Zhao, H., Palencia, A., Seiradake, E., Ghaemi, Z., Cusask,
S., Luthey-Schulten, Z., Martinis, S.A., (2015) Analysis of the Resistance Mechanism of a Benzoxaborole Inhibitor Reveals Insight into the Leucyl-tRNA Synthetase Editing Mechanism, ACS Chemical Biology,10(10):2277-85
Pang, Y.L., Poruri, K., Martinis, S.A., (2014) tRNA synthetase: tRNA aminoacylation and beyond, Wiley Interdiscip Rev RNA,
5(4):461-80
Yao, P., Poruri, K., Martinis, S.A., Fox, P.L., (2014) Non-catalytic regulation of gene expression by
aminoacyl-tRNA synthetases, Top Curr Chem,
344:167-87
Li, L., Palencia, A., Lukk, T., Li, Z., Luthey-Schulten, Z.A.,
Cusack, S., Martinis, S.A., Boniecki, M.T., (2013) Leucyl-tRNA synthetase editing domain functions as
a molecular rheostat to control condon ambiguity in Mycoplasma pathogens, Proc Natl Acad Sci U S A,
110(10):3817-22
Li, L., Martinis, S.A., Luthey-Schulten, Z., (2013) Capture and quality control mechanisms for
adenosine-5'-triphosphate binding, J Am Chem Soc,
135(16):6047-55
Palencia, A., Crepin, T., Vu, M.T., Lincecum, T.L. Jr,
Martinis, S.A., Cusack, S., (2012) Structural dynamics of the aminoacylation and
proofreading functional cycle of bacterial leucyl-tRNA synthetase, Nat Struct Mol Biol,
19(7):677-84
Sarkar,J., Poruri, K., Boniecki, M.T., Mctavish, K.K., Martinis, S.A., (2012) Yeast mitochondrial leucyl-tRNA synthetase CP1
domain has functionally diverged to accommodate RNA splicing at expense of
hydrolytic editing, J Biol Chem,
287(18):14772-81
Boniecki, M.T., Martinis, S.A., (2012) Coordination of tRNA synthetase active sites for
chemical fidelity, J Biol Chem,
287(14):11285-9
Sarkar, J., Martinis, S.A., (2011) Amino-Acid-Dependent Shift in tRNA
Synthetase Editing Mechanisms, J Am Chem Soc,
133(46):18510-13
Sarkar, J., Mao, W., Lincecum, T.L., Alley, M.R.K., Martinis, S.A., (2011) Characterization of Benzoxaborole-based Antifungal Resistance Mutations Demonstrates That Editing Depends on Electrostatic Stabilization of the Leucyl-tRNA Synthetase Editing Cap, FEBS Lett, 585 (2011):2986-91
Li Li, Boniecki, M.T., Jaffe, J.D., Imai, B.S., Yau,
P.M., Luthey-Schulten, Z.A., Martinis, S.A., (2011) Naturally Occurring Aminoacyl-tRNA
Synthetases Editing-Domain Mutations That Cause Mistranslation in
Mycoplasma Parasites, Proc.
Natl. Acad. Sci. U.S.A., 108(23):9378-83.
Boniecki, M.T., Martinis, S.A., (2010) The Balance Between Pre- and Post-transfer
Editing in tRNA Synthetases, FEBS Lett, 584(2):455-9
Mascarenhas, A.P., Martinis, S.A., (2009) A Glycine Hinge for tRNA-Dependent Translocation of Editing Substrates to Prevent Errors by Leucyl-tRNA Synthetase, FEBS Lett, 583(21):3443-7
Pang, YL., Martinis, S.A., (2009) A Paradigm Shift for the Amino Acid Editing Mechanism of Human Cytoplasmic Leucyl-tRNA Synthetase, Biochemistry, 48(38):8958-64
Boniecki, M.T., Rho, SB., Tukalo, M., Hsu, J.L., Romero, E.P., Martinis, S.A., (2009) Leucyl-tRNA Synthetase -Dependent and -Independent Activation of a Group I Intron, J Biol Chem, 284(39):26243-50
Hellmann, R.A., Martinis, S.A., (2009) Defects in Transient tRNA Translocation Bypass tRNA Synthetase Quality Control Mechanisms, J Biol Chem, 284(17):11478-84.
Boniecki, M.T., Vu, M.T., Betha, A.K., Martinis, S.A. (2008) CP1-dependent Partitioning of Pretransfer and Posttransfer Editing in Leucyl-tRNA Synthetase, Proc. Natl. Acad. Sci. U.S.A., 105, 19223-19228
Mascarenhas, A.P., Martinis, S.A. (2008) Functional segregation of a predicted "hinge" site within the beta-strand linkers of Escherichia coli leucyl-tRNA synthetase, Biochemistry, 47(16):4808-16
Splan, K.E.*, Musier-Forsyth, K.**, Boniecki, M.T.,
Martinis, S.A. (2008) In vitro
assays for the determination of aminoacyl-tRNA synthetase editing
activity, Methods,
44(2):119-28
*Department of Chemistry, Macalester College, **Department of
Chemistry, The Ohio State University
Karkhanis, V.A., Mascarenhas, A.P., Matinis, S.A. (2007) Amino Acid Toxicities of Escherichia Coli that are Prevented by Leucyl-tRNA Synthetase Amino Acid Editing, J. Bacteriol, 189(23):8765-8
Betha, A.K., Williams, A.M., Martinis, S.A. (2007) Isolated CP1 Domain of Escherichia Coli Leucyl-tRNA Synthetase is Dependent on Flanking Hinge Motifs for Amino Acid Editing Activity, Biochemistry, 46(21):6258-67
Vu, M.T., Martinis, S.A. (2007) A Unique Insert of a Leucyl-tRNA Synthetase is Required for Aminoacylation and Not Amino Acid Editing, Biochemistry, 46(17):5170-6
Zhai, Y., Nawaz, M.H., Lee, K.W., Kirkbride, E., Briggs, J.M., Martinis, S.A. (2007) Modulation of Substrate Specificity within the Amino Acid Editing Site of Leucyl-tRNA Synthetase, Biochemistry, 46(11):3331-7
Nawaz, M.H., Pang, Y.L., Martinis, S.A. (2007) Molecular and Functional Dissection of a Putative RNA-binding Region in Yeast MitochondrialLeucyl-tRNA Synthetase, J Mol Biol, 267(2):384-94
Karkhanis, V.A., Boniecki, M.T., Pururi, K., Martinis, S.A. (2006) A viable amino acid editing activity in the leucyl-tRNA synthetase CP1-splicing domain is not required in the yeast mitochondria, J Biol Chem, 281(44):33217-25.
Hsu, J.L., Rho, S.B., Vannella, K.M., Martinis, S.A.
(2006) Functional divergence of a
unique c-terminal domain of leucyl-tRNA synthetase to accommodate its
splicing and aminoacylation roles, J Biol Chem,281(32):23075-8.
Williams,
A.M. and Martinis,
Zhai,
Y. and Martinis, S.A. (2005) Two
Conserved Threonines Collaborate in the Escherichia coli Leucyl-tRNA
Synthetase
Amino Acid Editing Mechanism, Biochemistry, 44, 15437-15443.
Lincecum Jr., T.L. and
Martinis,
Mursinna, R.S., Lee, K.W.,
Briggs, J.M., and Martinis, S.A. (2004) Molecular Dissection of a
Critical
Specificity Determinant within the Amino Acid Editing Domain of
Leucyl-tRNA
Synthetase, Biochemistry, 43, 155-165.
Lincecum* Jr.,T.L., Tukalo*, M.,
Yaremchuk*, A., Mursinna, R.S., Williams, A.M., Sproat, B.S., Van Den
Eynde,
W., Link, A., Calenbergh, S. V., Grotli, M., Martinis*, S.A., and
Cusack*, S.
(2003) Structural and Mechanistic Basis of Pre- and
Post-Transfer
Editing by Leucyl-tRNA synthetase., Molecular Cell, 11,
951-963.
Mursinna, R.S. and Martinis,
Larkin, D.L., Williams, A.M.,
Martinis,
Nagaswamy, U., Gao, X.,
Martinis,
Larkin, D., Martinis,
Mursinna, R.S., Lincecum Jr.,
T.L., and Martinis,
Houman, F.,
Martinis,