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BFrancis.jpg (22520 bytes) Bettina Francis

I came into the department in 1997 from the Institute for Environmental Studies. My connections to the department are much deeper, however, since I worked for Bob Metcalf from 1978 to 1981 (on projects ranging from the delayed neurotoxicity of leptophos and developmental toxicity of azinphosmethyl, to integrated pest management for home and garden) and continued to work with him thereafter. My research in pesticide toxicology has ranged from structure-activity relationships in the delayed neurotoxicology of organophosphate ester insecticides to the developmental toxicity of diphenyl ether herbicides, which is my current interest. Certain diphenyl ethers, including the herbicide nitrofen, cause an unusual constellation of malformations in mice and rats. The nature of the malformations strongly suggests that these compounds act on expression of developmentally specific genes. Identifying these genes is my current goal. I also have an ongoing interest in the environmental toxicity of synthetic chemicals—that is, in their effects on species other than humans and livestock. One course I teach, Toxic Substances in the Environment (ENT 331), is an overview of both the ecological and human health effects of environmental pollutants. The Wiley volume by the same name is being updated for a second edition. The class notes for the second course I teach, Pesticide Toxicology (ENT 333), will eventually become a book as well.

Entomology Integrative Biology University of Illinois

Updated 12/08/99