We seek to determine the degree to which the structure, character, and dynamics of the process of development predisposes the system to produce certain forms instead of others.learn more
limb congenital malformations
We use non-model mammals as “natural mutants” to identify mutations that contribute to the generation of divergent limb phenotypes in humans with congenital limb malformations.learn more
We seek to identify regulatory innovations that have driven the evolution of gene expression and limb form in mammals including opossums, bats, mice, and pigs.learn more
We seek to identify the main biological forces in the genome, during development, and in anatomy that promote the success of bats in adapting to their changing environments.learn more
We are studying the genetic and developmental mechanisms that drove the parallel reduction of digits in several mammals (cows, pigs, camels, deer, horses, dogs, and cats).learn more
We are using the opossum (Monodelphis domestica) as a new, mammalian system to uncover the developmental basis of thalidomide teratogenesis.learn more
- Devo-evo studies of the role of development in shaping evolutionary change.
- Organism-driven studies in evo-devo.
- Multi-disciplinary approaches (paleontology, developmental genetics, genomics, mathematics, systems biology, field-work, etc.).
- Non-traditional mammalian model systems (bats, pigs, opossums, deer, horses, etc.).
- Spans the levels of the biological hierarchy (individual, within-species, among-species, etc.)
- Diverse team of collaborative researchers (math, compsci, genomics, bioe, devbio, functional morphology, phylogenetics, etc.).