Yoshie Hanzawa


Plant Biology Affiliate

Assistant Professor of Crop Sciences
Institute for Genomic Biology
259 Edward R. Madigan Laboratory MC-051
(217) 333-4685



Senior researcher, 2006-9, NYU

Postdoctoral researcher, 2000-6, John Innes
    Centre, UK

Ph.D. 2000, Hokkaido University

B.Sc., 1995, Hokkaido University




CPSC 452  Evolutionary Genetics and Genomics



     Our goal is to understand evolution of genetic networks in plants. We target the flowering gene network, one of the best-understood molecular networks in plants, and ask How have the Molecular Mechanisms in the Flowering Gene Networks Evolved? We use a combination of evolutionary genomics, molecular genetics, and population genetics approaches comparatively in Arabidopsis thaliana and soybean, aiming to develop superior plants that are highly adaptive to diverse environments. Currently on-going projects are listed below.


     Population genetics of flowering genes in Arabidopsis thaliana. We have elucidated polymorphisms of 52 flowering genes in wild Arabidopsis thaliana accessions using a population genetic approach. Currently, we focus on the cis-regulatory evolution of CONSTANS, a central gene in the photoperiod-regulated flowering pathway.


     Molecular evolution of FT and TFL1 in Arabidopsis thaliana. Flowering genes FT and TFL1 are homologous, but their actions are antagonistic. To understand molecular basis of functional divergence of FT and TFL1, we study functions of their interacting proteins using molecular genetic approaches.


     Transcriptome analysis of photoperiodic flowering response in soybean. Unlike Arabidopsis thaliana, soybean responds to short day-length to switch to flowering. To understand the molecular nature of the photoperiod flowering response of soybean, we have initiated expression study of flowering genes in soybean using qRT-PCR, and the genome-wide gene expression analysis using the illumina and the 454 sequencing machines.




Wickland, D.P. and Hanzawa, Y. (2015) The FLOWERING LOCUS T / TERMINAL FLOWER 1 Gene Family: Functional Evolution and Molecular Mechanisms. Molecular Plant.


Rosas, U., Mei, Y., Xie, Q., Banta, J., Seufferheld, G., Gerald-Martinez, S., Chou, L., Bhambra, N., Parks, J.D., Flowers, J., McClung, C.R., Hanzawa, Y. and Purugganan, M.D. (2014). Variation in Arabidopsis flowering time associated with cis-regulatory variation in CONSTANSNature Commun. 5:3651-3658. 


Wu, F., B. Price, W. Haider, G. Seufferheld, R. Nelson, and Y. Hanzawa. (2014). Functional and Evolutionary characterization of the CONSTANS gene family in short-day photoperiodic flowering in soybean. PLOS ONE 9: e85754.


Wu, F. and Hanzawa, Y. (2014). Photoperiodic control of flowering in plants. Handbook of Plant and Crop Physiology the 3rd edition, CRC Press, Taylor & Francis Group, LLC.