Research Ethics and Responsibilities
(http://www.life.uiuc.edu/mcb/580/)

Molecular and Cellular Biology 580
University of Illinois at Urbana-Champaign
Spring 2009

Wednesdays
January 28 – March 11, 2009
7:00 – 9:50 pm
Chemical & Life Sciences Laboratory Auditorium
(this differs from the Schedule of Classes)


Contents of This Page


Course Organization

Registration:

Title: Research Ethics and Responsibilities
Course Rubric:
MCB 580
Course Reference Number (CRN): 38677
Prerequisite: Graduate standing in MCB or consent of instructor
Credit: 1 Hour Credit, S/U Grade Only
Time: Wednesday evenings 7:00–9:50 PM, January 28 through March 11, 2009

Place: Chemical & Life Sciences Laboratory Auditorium

Instructors:

Gary Olsen gary@life.illinois.edu Department of Microbiology, B103 Chemical & Life Sciences Laboratory, MC-110
Stephen Farrand stephenf@life.illinois.edu Department of Microbiology, B103 Chemical & Life Sciences Laboratory, MC-110
Rutilio "Rudy" A Fratti rfratti@illinois.edu Department of Biochemistry, 419 Roger Adams Laboratory
Guest Lecturers (subject to change):
Bob Wengert
C. K. "Tina" Gunsalus
Nick Tsiakais
Janice Bahr
Lyndon Goodly
Required Text:
Macrina, F. 2005. Scientific Integrity, Third edition. American Society for Microbiology Press, Washington, D.C.

Course Format:

Most weeks class will be divided into two sessions covering different topics. A "typical" session will be:

Attendance is mandatory. If you are absent from a class, a make-up paper on the topics covered during the missed class will be required. Failure to make-up for a missed class by turning in the required paper or more than one absence will result in an unsatisfactory grade. (Because this is a short course, missing 2 weeks would mean missing nearly 30% of the material and discussion. We cannot excuse more than one absence.)

Make-up papers should be 5–7 pages (typed, 11 or 12 point font, double-spaced, 1 inch margins; this means 1500–2000 words). The paper should focus on the topics missed, describing relevant issues, potential problems, and acceptable practices. The textbook and online materials should provide the background for the paper. All references used should be cited. (Think about it: this is an ethics course.) Following the discussion of the topics, the paper should apply the principles discussed to the case studies presented in the missed class (copies can be obtained from one of the course instructors). The paper should be of suitable clarity and perspective that it would provide a concise overview of the topics to a reader who is unfamiliar with the topics. The paper will be evaluated by the instructors, and if it is not of acceptable quality it will be returned to be rewritten.

Course Grades:
An S/U grade will be assigned based upon attendance, the in-class writing assignments, participation and completion of assigned on-line training.


Course Schedule (Spring 2009)

(subject to change)

January 28

  1. Introductory Comments (presentation as PDF) — Gary Olsen

  2. Ethics (ouline as PDF, questionaire as PDF) — Bob Wengert
    Macrina Chapter 2
    1. Ethics: What is it (and what is it not)
    2. Ethics versus morality
    3. Questionnaire on what is ethical versus not (or right versus wrong)

  3. Ethics, Science and Society (presentation as PDF, Course Agreement (which must be turned in by all students)) — Gary Olsen
    Macrina Chapters 1 and 2
    1. Scientific ethics
    2. Scientific integrity
    3. Scientific misconduct: Fabrication, falsification, or plagiarism (full definition)
    4. Fraud
    5. Social perspectives of science and scientists
    6. Responsibility of scientists to society (On Being a Scientist)
    7. Elevating Science, Elevating Democracy — Essay by Dennis Overbye, New York Times

  4. Homework: Complete (if necessary) your "General Lab Safety Training", and bring a copy of the certificate to class on Feb. 4 (see details below).

February 4

  1. Laboratory Safety and Compliance (presentation as PDF)— Nick Tsiakais
    All students are required to take the University of Illinois at Urbana-Champaign Division of Research Safety "General Lab Safety Training".
    A copy of the certificate should be turned in by this (February 4) class meeting. Most of you will have already done this, so it is only necessary to print a copy of the certificate. Please make it a copy, we will not return them.
    1. Basic Laboratory Safety (HHMI)
    2. Biohazards (CDC)
    3. Recombinant DNA (NIH)
    4. Hazardous chemicals
    5. Transfer of etiologic agents
    6. Radioactivity (UIUC)
      • Safe handling of radioactive materials
      • Regulations

  2. Scientific Ethics in the News: Case 1 — Stephen Farrand

  3. Homework: Complete the NIH training "Protecting Human Research Participants", and bring a copy of the certificate to class on Feb. 11 (see details below).

February 11

  1. Animal Use (and human subjects) — Lyndon Goodly
    Macrina Chapters 5 and 6, and Appendix IV
    All students are required to complete the NIH Office of Extramural Research
    "Protecting Human Research Participants".
    A copy of the certificate should be turned in at this class meeting (February 11). Please make it a copy, we will not return them.
    1. Laboratory animals
    2. Human subjects

  2. Scientific Ethics in the News: Case 2 — Rudy Fratti

February 18

  1. Dealing with Problems — C. K. "Tina" Gunsalus
    1. Ethical research
    2. Academic misconduct
    3. How and where to report problems
    4. Who you can turn to for support, advice and help
    5. Harassment
    6. Questions and discussion

  2. The Mentor/Student Relationship — Stephan Farrand
    1. The Nature of Research
    2. The Mentor/Student Relationship

February 25

  1. Conflict of Interest and Conflict of Commitment — Janice Bahr
    Macrina Chapters 7 and 9, and Appendix V
    1. Conflict of interest and conflict of commitment (UIUC)
      • Conflict of commitment — external activities that interfere with an individual's responsibility to the University
      • Conflict of interest — situations that may benefit an individual or the individual's family to the detriment of the University
      • Conflict of interest disclosure
    2. Intellectual property
      • Intangible — ideas, inventions, discoveries
      • Protections — patent, copyright, trademarks, etc.
      • Intellectual property rights (University of Illinois)
        • If conceived or developed by an employee or student during work or on University business — University retains ownership of inventions
        • Traditional academic work done independently on the individual's own initiative — individual retains ownership of copyright
        • Work done as part of assigned University duties — University retains ownership of copyright

  2. The Results of Research: Notekeeping and other important issues — Rudy Fratti
    Macrina Chapters 9 and 11, and Appendix VI
    1. Notekeeping
      • Verification
      • Repetition
    2. Data ownership
      • For federally funded research, the institution legally owns the data
      • Most responsibility for the data delegated to the Principal Investigator
    3. Legal ramifications — The Baltimore case
    4. Case study — Who owns the data?

March 4

  1. Grant proposals and Scientific Review (presentation as PDF) — Gary Olsen
    Macrina Chapter 4
    1. Grant proposals
    2. Peer review of manuscripts
    3. How ethical problems arise
      • Financial conflicts
      • Intellectual conflicts
      • Personal conflicts
      • Confidentiality

  2. Scientific Communication — Stephen Farrand
    Macrina Chapter 4
    1. Presenting your work: seminars and publications
    2. Allocation of credit
    3. Authorship
    4. Materials on presenting your work from The American Physiological Socienty

March 11

  1. Career Night: Options for your life with a degree
    • Guests:
    • TBA


Some Useful Published Resources


Some Useful Internet Resources


This page is maintained by Gary Olsen. Please send any comments, suggestions or questions to: gary@life.uiuc.edu
Last modified April 16, 2009