A very tentative outline of the course schedule is listed below. Check for schedule changes and announcements regularly at the MCB 421 web site. Despite the best intentions, there are often changes in the schedule during the course. You ARE responsible for material presented in guest lectures and the material will be on the exams.
| Tue Aug 23 |
What Is Genetics and Why Do It? |
| Thur Aug 25 |
Chromosomes, Plasmids, and Phage; Sources of Genetic Variation; Mutants and Mutations |
| Tue Aug 30 |
Spontaneous Mutations, Mutator Strains, and Mutagens |
| Thur Sept 1 |
Isolation of Mutants; Selections, Screens and Enrichments |
| Tue Sept 6 |
Homologous Recombination No class: See Kuzminov lecture online. |
| Thur Sept 8 |
Isolation of Mutants; Selections, Screens and Enrichments continue. |
| Tue Sept 13 |
Reversion and Intergenic Suppression |
| Thur Sept 15 |
Interaction and Bypass Suppressors |
| Tue Sept 20 |
Complementation, cis-trans tests, Negative Complementation |
| Thur Sept 22 |
Generalized Transduction |
| Tue Sept 27 |
Generalized Transduction |
| Thur Sept 29 |
Exam #1 |
| Tue Oct 4 |
Phage- Lytic Growth; Host Restriction and Modification Systems and Other Defenses |
| Thur Oct 6 |
Lysogeny |
| Tue Oct 11 |
Site-specific Recombination |
| Thur Oct 13 |
Site-specific Recombination and Specialized Transduction |
| Tue Oct 18 |
Discovery and Properties of Transposable Elements |
| Thur Oct 20 |
Research Applications of Transposons |
| Tue Oct 25 |
Protein-based Measurements of Gene Expression: Operon and Gene Fusions; Reporter Genes |
| Thur Oct 27 |
Exam #2 |
| Tue Nov 1 |
RNA-based Measurements of Gene Expression |
| Thur Nov 3 |
Site-directed Mutagenesis |
| Tue Nov 8 |
Site-directed Mutagenesis |
| Thur Nov 10 |
Developing New Bacterial Genetic Tools and Applying Genetics to New Systems |
| Tue Nov 15 |
Conjugation #1- Dr. Steve Farrand |
| Thur Nov 17 |
Conjugation #2- Dr. Steve Farrand |
| Nov 21 - 27 |
Thanksgiving Break |
| Tue Nov 29 |
Conjugative Transposons |
| Thur Dec 1 |
Exam #3 |
| Tue Dec 6 |
Exams Back, Discuss Grades |
| Wed, Dec 14 |
Final Exam 8:00 to 11:00 AM |
