MCB 250
Molecular Genetics
School of Molecular and Cellular Biology
University of Illinois at Urbana-Champaign
kirchner@life.uiuc.edu | wilson7@illinois.edu | martys@illinois.edu
course
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Lecture Material

Lecture Syllabus

  • Lecture Syllabus with assigned readings
  • Tentative Course Syllabus & Lectures

    Day Date Instructor Lecture Slides
    W 21 Jan. Wilson  1: Introduction to MCB 250; The Central Dogma PPT  PDF
    F 23 Jan. Wilson  2: Chemical Basis of Molecular Biology
    PPT  PDF
    M 26 Jan. Wilson  3: DNA Structure PPT  PDF
    W 28 Jan. Wilson  4: DNA Structure and Analysis PPT  PDF
    F 30 Jan. Wilson  5: Methods for Studying DNA PPT  PDF
    M 2 Feb. Wilson  6: Protein Structure PPT  PDF
    W 4 Feb. Wilson  7: Protein Structure; Protein Folding PPT  PDF
    F 6 Jan. Wilson  8: Methods for Studying Proteins; Protein Purification PPT  PDF
    M 9 Feb. Wilson  9: DNA Supercoiling PPT  PDF
    W 11 Feb. Wilson  Optional Review Session (1:00 PM; 141 Wohlers Hall)
    W 11 Feb. Examination I (7:00–9:00 PM) Room assignments posted on the course website.
    F 13 Feb. Wilson  10: Chromosome Structure; DNA Condensation PPT  PDF
    M 16 Feb. Wilson  11: DNA Replication PPT  PDF
    W 18 Feb. Wilson  12: Replication Initiation and Termination; Telomeres and Telomerase PPT  PDF
    F 20 Feb. Wilson  13: RNA Structure; Transcription in Prokaryotes PPT  PDF
    M 23 Feb. Wilson  14: Transcription in Prokaryotes; Processing of rRNA and tRNA PPT  PDF
    W 25 Feb. Wilson  15: Transcription in Eukaryotes PPT  PDF
    F 27 Feb. Wilson  16: Transcription in Eukaryotes; mRNA Splicing PPT  PDF
    M 2 March Wilson  17: Translation in Prokaryotes; The Genetic Code PPT  PDF
    W 4 March Wilson  18: Translation in Eukaryotes PPT  PDF
    F 6 March Wilson  19: Mutation and DNA Repair PPT  PDF
    M 9 March Wilson  20: Homologous Recombination; Nonhomologous End Joining PPT  PDF
    W 11 March Wilson  Optional Review Session (1:00 PM; 141 Wohlers Hall)
    W 11 March Examination II (7:00–9:00 PM) Room assignments posted on the course website.
    F 13 March Shankland  21: What is a Gene?        
     (5:00 PM Deadline to drop course without a grade of W)
    M 16 March Shankland  22: Molecular Analysis of Genes
    W 18 March Shankland  23: Molecular Analysis of Gene Expression
    F 20 March Shankland  24: Overview of Gene Regulation
    M-F 23-27 March Spring Break- No classes
    M 30 March Shankland  25: Transcriptional Regulation in Bacteria; Part I
    W 1 April Shankland  26: Transcriptional Regulation in Bacteria; Part II
    F 3 April Shankland  27: Propagation of Bacteriophage lambda, Part I
    M 6 April Shankland  28: Propagation of Bacteriophage lambda, Part II
    W 8 April Shankland  29: Transcriptional Regulation in Eukaryotes
    F 10 April Shankland  30: Differential Gene Expression and Cell Differentiation
    M 13 April Shankland  31: Transgenes in Medicine and Agriculture
    W 15 April Shankland  Optional Review Session (1:00 PM; 141 Wohlers Hall)
    W 15 April Examination III (7:00–9:00 PM) Room assignments posted on the course website.
    F 17 April Shankland  32: Transgenes as Research Tools
    M 20 April Shankland  33: Transposable Elements
    W 22 April Shankland  34: Gene Regulatory Networks
    F 24 April Shankland  35: Epigenetic Gene Regulation
    M 27 April Shankland  36: Post-transcriptional Regulation in Bacteria
    W 29 April Shankland  37: Post-transcriptional Regulation: RNA Interference in Eukaryotes
    F 1 May Shankland  38: Regulation of Gene Expression by Alternative Splicing
    M 4 May Shankland  39: Gene Rearrangements in the Vertebrate Immune System
    W 6 May Shankland  40: Evolution of Genomes and Genes
    W 6 May Shankland  Optional Review Session: Time and Location TBA
    W 13 May Final Exam (7:00-10:00 PM) Room assignments posted on the course website.
    Lecture schedule and topics are subject to change and will be announced during the class lectures and posted on the Announcements page.
    **Note that Exams may cover lecture material or lecture discussions that may not necessarily be found in the book chapters or assignments. It will be important to attend each lecture to obtain complete materials in preparation for your exam.