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Questions in Lysosomes
Page 2 out of 4 Pages
- Why is the pH lower in the early endosome? This endosome does not have acid hydrolases so how is the pH lowered here?(6259 views)
- During class, you stated that there are 40 digestive enzymes present in the lysosome. However, the reading from the Cooper book on page 424 states that there are 50. Are there ten that aren't that important or was this just a slight error? (3076 views)
- I think you said that some macromolecules can begin to be degraded in the late endosome, but none will be completely degraded until the lysosome is fully created. Is this because the pH of the late endosome is not yet 5, or is there some other reason why macromolecules cannot be completely degrated in the late endosome? (5600 views)
- For a question, it said that the nucleotide is the least likely to be degraded by the lysosome. Why is that?
(3237 views)
- In lecture you gave the example of insulin as the signal that needed to be degraded in a lysosome when the cell had brought in adequate amounts of glucose. If the insulin remains and continues to signal the cell that it should bring in glucose how does the cell know that it has enough glucose and should degrade the insulin?(5975 views)
- What do prokaryotes do to get rid of waste? (8705 views)
- I think you said that the lower pH in the late endosome triggers the mannose-6-phosphate receptores to release the acid hydrolases. What triggered the signal receptors from the plasma membrane to release the signal molecules in the early endosome? (6411 views)
- How are proton pumps incorporated into the membrane of the early endosome (it seems unlikely that the endosome would have translocons to insert transmembrane proteins)? (5586 views)
- The diagrams in the lecture show the lysosome as being much smaller than the endosome. Why are lysosomes smaller than endosomes? (5359 views)
- Are phagosomes and autophagosomes considered endosomes?
(15356 views)