DNA Structure and Replication

ID #1720

The nucleosome (core) has 146 DNA base pairs surrounding the 8 histones. The chromatosome has 166 base pairs surrounding the 8 histones and binding the H1 histone. Do the 20 DNA base pairs come about because they link the H1 histone to the core?

146 is the number of base pairs wrapped around the core of histones in a nucleosome. When you incorporate Histone H1 in addition to the nucleosome, and add the base pairs that are associated with H1 that aren't part of the nucleosome, you add another 20 to that total. This is now 166 base pairs, the amount of DNA associated with what we call a chromatosome.

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