DNA Structure and Replication

ID #1694

In a typical mitotic chromosome there are one pair of sister chromatids, one centromere and two telomeres for each sister chromatid. Why is that?

Each mitotic chromosome has already undergone replication, which means it's actually two identical double helices, held together at the centromere as a pair. We call each individual double helix in this pair a chromatid, so a mitotic chromosome is a pair of sister chromatids. And regardless of the level of winding, looping, packing, etc., each end of every linear DNA molecule has a telomeric region. Four "arms" equals four telomeres.

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