DNA Structure and Replication

ID #1143

Are histones basic and negatively charged? If they are, why are histones attracted to DNA, if DNA contains negatively charged phosphates?

Remember from way back at the beginning of the semester, basic amino acids carry a positive charge. So yes, they're basic, but no, they're not negatively charged. Otherwise, you're absolutely right -- they wouldn't be attracted to the negatively charged DNA backbone.

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