DNA Structure and Replication

ID #2356

Can someone explain what Mr. Mehrtens was saying about replicons, ori, and foci. I need help sorting out which ones give way to which ones.

A replicon is the amount of DNA replicated from a single ori. Since bacteria only have one ori, they only have one replicon. The human genome has approximately 30,000 ori, so there will also be 30,000 replicons. A focus of replication is a grouping of oris that are brought to the replication machinery. Each focus of replication contains approximately 200-300 ori, so 200-300 replicons. I mentioned that the human genome has about 30,000 oris, so one would predict that there would be about 100 foci of replication. 

Categories for this entry

Print this record Print this record
Send to a friend Send to a friend
Show this as PDF file Show this as PDF file
Export as XML-File Export as XML-File