DNA Structure and Replication

ID #1134

I was just wondering what exactly major grooves and minor grooves in the DNA strand are?

The grooves in a double helix are analogous to the threads in a screw you'd find at a hardware store. If you look at the screw from the end, it has a uniform diameter, right? But if you look at it from the side, it has ridges and grooves. The same concept holds for a double helix. The difference is, the "threads" are not spaced evenly -- they alternate as large and then small, then large and then small. These are the major and minor grooves.

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