DNA Structure and Replication

ID #2225

Are Okazaki fragments unique to eukaryotes? Or is it universal, so it's present in bacterial DNA replication as well?

Yes, since DNA replication in prokaryotes and eukaryotes is bidirectional, there will be leading and lagging strand synthesis in both types of organisms. Okazaki fragments are present in both prokaryotes and eukaryotes. In fact, the formation of Okazaki fragments is commonly studied in bacteria like E. coli since they are easier to work with. Remember that eukaryotes have multiple origins of replication and bacteria only have one ori, but nucleic acid synthesis is universal in eukaryotes and prokaryotes. 

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