DNA Structure and Replication

ID #1118

Could you explain the role of sister chromatids during interphase of chromosome replication?

DNA replication occurs during interphase -- specifically during a period called "S phase" (the S stands for synthesis). Prior to S-phase, there are no sister chromatids, just single chromosomes. As previously explained, you may have maternal and paternal copies of those single chromosomes, but the point is they each exist as a single double helix (with associated protein of course). During S-phase, every chromosome is replicated, so at the conclusion of S-phase (still in interphase, by the way), you now have two double helices for every one that you started with. These identical daughter double helices created from replication of the parental double helix are called sister chromatids.

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