DNA Structure and Replication

ID #2158

Do eukaryotic circular DNA (such as in the mitochondria DNA) supercoil as well, or is supercoiling unique to bacteria?

I did a little bit of research about mitochondrial DNA packaging and it appears that they do things a bit differently from both what we studied in prokaryotes and eukaryotes, and they do not use histone proteins. They form structures call nucleoid structures.  Keep in mind that topoisomerases are not only used in prokaryotes.  Both prokaryoes and eukaryotes use topoisomerases, for example to relieve the twisting induced at the replication forks.

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