DNA Structure and Replication

ID #2072

Is the sequence of the ori universally the same (the same in all organisms)?

No. Related organisms will have similar ori sequences, but species tend to have their own specific ori. One thing that they all have in common--and I mean bacteria, archae, and eukaryotes--is that they are A-T rich regions. Is this a coincidence? Not at all. If the ori is your "start signal" that signifies where you're supposed to begin separating the strands, doesn't it make sense that this region would be easier to separate by having more A-T base pairs than G-C base pairs?

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