DNA Structure and Replication

ID #2068

Why would 5' GGACTTGACATCACC 3' and not 5' CTACAGTTCAGG 3' hybridize to the following sequence: 5' GGTGATGTCAAGTCC 3'


Because ds-DNA is antiparallel, so the 3' end of one strand is at the same end of the molecule as the 5' end of the other strand. You have to take a sequence given to you in the 5'-3' direction and turn it around to the 3'-5' direction to line them up.

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