Energy and Metabolism

ID #1082

I understand that oxidative phosphorylation is forming ATP through the ETC. So is substrate level phosphorylation whenever ATP is produced outside of the ETC, or only under anaerobic conditions (glycolysis but not Kreb's)?

You were right with your first answer. There's only two ways for a cell to make ATP. One is by harnessing the power of a proton gradient (that's oxidative phosphorylation), and the other is by directly phosphorylating ADP using the energy released by a coupled exergonic reaction (that's substrate level phosphorylation). There are examples of SLP reactions in both glycolysis and Krebs cycle.

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