Energy and Metabolism

ID #1081

I was confused about the classification of NAD+/NADH. Is this strictly a coenzyme, or could it technically be a nucleotide based on its conformation?


It is strictly a coenzyme. By definition, a nucleotide is a building block of a nucleic acid, and that odd dinucleotide structure isn't something that you'd find in a nucleic acid for a number of reasons. For one, nicotinamide isn't a purine or pyrimidine base. And nucleic acids don't have their phosphates covalently linked together.

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