Energy and Metabolism

ID #2196

In the aerobic respiration, I understand the energy cost for moving 2 NADH (which comes from glycolysis) into the mitochondrial matrix, but what about the pyruvate molecules that need to be transported into the matrix from cytoplasm? What is the ATP cost of this 'movement? And do we need to deduct those ATPs from the total 36 ATPs produced from the complete oxidation of glucose via aerobic respiration?

There is a mitochondrial pyruvate transporter protein that helps move pyruvate into the matrix.The details of this transport and energy requirements are outside the scope of this class, so for the purposes of MCB 150, you will only be responsible for the material presented in one of the lecture slides from Lecture 11, illustrating the theoretical calculated ATP production from the full oxidation of glucose. Based on this calculation, you are correct in saying that we need to pay a molecule of ATP for every NADH molecule that passes through the mitochondrial membrane, moving from the cytoplasm (where they were produced at the end of glycolysis) towards the mitochondrial matrix.

Print this record Print this record
Send to a friend Send to a friend
Show this as PDF file Show this as PDF file
Export as XML-File Export as XML-File