Lipids and Biomembranes

ID #1763

When talking about lipid composition on fluidity, how does the incubation time change when we change compositions in a cell (for example the amount of cholesterol). For example, when there is a human cell and a mouse cell that fuses into the hybrid cell, how do we know the time required to get to the end of the experment - more or less time?

Consider what happens to membranes when you change a variable, like lengthening their fatty acid tails or increasing the number of double bonds, and determine if that makes the membrane more or less stable. Then for this experiment in particular, the researcher is asking the question "are molecules free to move around in this membrane?" It would seem that the more stable the membrane is, the more restricted its molecules would be in movement, and the longer the time it would take for a given molecule (like a fluorescently-labeled protein) to get from "point A" to "point B".

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