Nucleic Acid Structure and General Features

ID #2234

What is the difference between the hydrogen bonds between base pairs and base-stacking interactions? I know that AT pairs have two hydrogen bonds and GC pairs have three, but what about base-stacking interactions?

Base-stacking interactions are hydrophobic interactions between the bases on each strand to minimize interaction of these bases with water. It is sort of like stacking plates - the rings of the different bases stack on top of each other. It is not specific; rather, the combined effect of so many stacked bases helps to stabilize the whole double helix. 

Categories for this entry

Print this record Print this record
Send to a friend Send to a friend
Show this as PDF file Show this as PDF file
Export as XML-File Export as XML-File