Proteins and Enzymes

ID #1607

can the individual amino acids have N-terminus or just the protein as a whole?


Once any amino acid gets incorporated into a protein--other than the very first amino acid--it no longer has a free (i.e. unoccupied) amino group (which, depending on the actual conditions will be either NH3+ or NH2). Only the first amino acid in a polypeptide chain will retain a free amino group, just as only the last amino acid in the polypeptide chain will retain a free carboxyl group.

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