Proteins and Enzymes

ID #1045

How do enzymes increase the probability that a substrate will be close to another to react?

Remember that not only do the substrate molecules have to collide, they have to be in the proper orientation. Also remember that there is going to be more than a single molecule of enzyme present in the cell -- probably lots. So if an enzyme "gobbles up" a substrate molecule, it increases the probability that when the other substrate is encountered, the collision will be favorable. Since this same event is happening all over the cell (or organelle), substrates rapidly get converted to products.

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