Proteins and Enzymes

ID #2385

On one of the slides from lecture 6 that mentioned how enzymes decrease activation energy, it says that "Some enzymes accept reactive groups from one substrate molecule and donate it to another substrate molecule." Can anybody please elaborate upon this point? I don't understand it entirely.

Sometimes a reactive group (e.g. a phosphate group) will temporarily be bound to the enzyme. In the "phosphate" example I am describing, a phosphate molecule from a particular substrate will be attached to the enzyme for a little while, and then the enzyme will break its bond with the phosphate group and will attach the phosphate to another substrate. Ultimately, the enzyme will remain unchanged because it only temporarily accepts the phosphate group. 

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