Proteins and Enzymes

ID #2377

Is Alzheimer's not considered a spongiform encephalopathy?


Alzheimer's is a disorder caused by misfolded proteins, but is not caused by the prion protein. Only the disorders caused by misfolded prion lead to symptoms like what you find in mad cow, scrapies, chronic wasting disease, etc. When the brain of someone who had the disorder degenerates, it doesn't look like a sponge. There are plaques in the brain tissue, but it's not the same thing as a spongiform encephalopathy. 

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