Proteins and Enzymes

ID #2186

What exactly is the use of Sulfa drugs - I understand that it inhibits the DHPS enzyme but how does this help humans?


DHPS is an enzyme that is found only in bacteria. When it is inhibited by sulfanilamide, a type of sulfa drug, it can't synthesize folic acid. If the bacteria can't synthesize folic acid, it can't survive. So if a human has a bacterial infection, treatment with sulfanilamide should kill the bacteria without killing the person! 

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