Microtubules

ID #1950

"Tubulin dimers with nucleoside diphosphates in their nucleotide binding site(s) have a lower affinity for each other than tubulin dimers with nucleoside triphosphates in their nucleotide binding site(s)." Does this mean that both the alpha and the beta tubulin have GDP?


No, you can safely assume that since the GTP in the alpha subunit never gets hydrolyzed, you should only consider the nucleotide that will be hydrolyzed under the appropriate conditions.

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