ID #1354

I was wondering about a couple slides from one of the microtubules lectures. I have writen down that vesicle trafficing along microtubules can move in either direction by disengaging one motor protein and engaging the other, meaning kinesin and dynein. One a couple slides previous to this i have writen that dynein and kinesin are usually found in pairs or groups. Does this mean that in the pair there will be one dynein and one kinesin? Is that how vesicles can change direction along the motor protein so easily?

Good question, but no. When I meant that a given motor protein is typically found in pairs, I meant a pair of kinesins with their tails wrapped around each other, or a pair of dyneins with their tails wrapped around each other. I wasn't implying one kinesin motor physically attached to one dynein motor. If you wanted a vesicle or organelle to be able to move in either direction, you'd need a pair of each.

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