Microtubules

ID #1338

What exactly to vincristine and vinblastine do? I have that they do the exact same thing as Colchicine and Colcemid, but for actively dividing cells, but how do they select the cells that are dividing and which ones aren't?


They, like colcicine and colcemid, bind free tubulin and induce depolymerization of all MTs (that don't have their ends occupied). How they target rapidly dividing cells, I don't know.

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