Microtubules

ID #2279

Does taxol also target rapidly dividing cells like vincristine and vinblastine?


Taxol is used similarly to vinca-alkaloids (vincristine and vinblastine), but it works differently. While the vinca-alkaloids prevent microtubule assembly during cell division, taxol stabilizes microtubules to the point that they can't be taken apart to recycle the dimers to correctly prepare the cell for division. 

Since both approaches inhibit cell division, both approaches are effective at targeting rapidly dividing cell populations. 

Print this record Print this record
Send to a friend Send to a friend
Show this as PDF file Show this as PDF file
Export as XML-File Export as XML-File