Actin and Myosin

ID #1961

I understand that actin and myosin work together during cytokinesis. I'm not sure exactly how it works though--myosin somehow pulls the actin tighter, and then the actin tail that is being exposed because of the tightening depolymerizes (just because the cell makes the conditions right)? And does this mean actin and myosin are interacting in the extracellular space, on the outside of the cell during cytokinesis?

Your understanding of this is excellent right up to the location part. This is all happening inside the cell with the actin contractile ring attached to the cytosolic face of the cytoplasmic membrane. It would just be too hard to regulate this process if we had to export the machinery out of the cell and do it outside.

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