Actin and Myosin

ID #1874

In class you mentioned Actin Binding Proteins that bind to globular actin to prevent them from polymerizing. Can the protein at the end of a microvilli that binds to the F actin also be considered an ABP? If so, is it the same ABP?


The answers are yes for the first one one and no for the second one. An "actin binding protein" is a fairly generic term that just means any protein that can associate with actin. That terminology isn't even specific enough to distinguish between ABP's that bind to G-actin, and those that bind to F-actin, like the ones you correctly postulated were at the end of a microvillus.

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