Lysosomes

ID #1303

It seems as if the 50 hydrolases are randomly sent to any late endosome to start degrading material. For example, if there is only nucleic acid inside of an endosome, how does the signaling work to get only nuclease to travel there? Is there ever a waste of the assorted hydrolases in lysosomes?


The cell doesn't try to anticipate what might be in an endosome/lysosome when it's preparing hydrolases. Better to have all the tools and not need all of them than to only make some and wish you had one of the others. All those hydrolases might not be needed when the lysosome is first called into duty, but prior to its self-degradation, it will probably have encountered enough material to make it worth the effort in making all those enzymes.

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