Lysosomes

ID #1298

Is the mannose 6 phosphate protein sitting in the trans side of the golgi apparatus actually the acid hydrolase that will be added to the late endosome?


I'm not sure which one of the protein molecules in that figure you're referring to. If you're talking about the transmembrane protein in the trans Golgi, then no, that's the mannose-6-P receptor, not the acid hydrolase. The acid hydrolase--which is displaying the mannose-6-P group--is the yellow "bead-like" molecule that binds to the receptor and gets sent to the late endosome. (At least I think it's yellow; I don't have that slide in front of me right now)

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