Lysosomes

ID #2461

In the 5th slide of lecture29, the receptors that are recycled go to recycling endosome and then eventually gets ejected out of the cell. However in the next slide, the recycled receptor molecule goes to Golgi apparatus. Which diagram is correct? I'm confused. Is it the mannose-6-P receptor that goes to Golgi to be recycled? If so, does it go through a recycling endosome or just straight to the Golgi?


The fifth and sixth slides of Lecture 29 show two different types of receptor molecules that perform their functions in different places. The fifth slide shows the recycling of a receptor that recognizes extracellular molecules like signals. They are recycled back to the plasma membrane so that they can bind additional signal molecules. The next slide shows the recycling of M6P receptors, which are recycled back to the trans face of the Golgi so that they can bind more acid hydrolases being targeted to the lysosome. I think they can go straight back to the trans face of the Golgi and do not need to go to a recycling endosome first. 

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