Endoplasmic Reticulum

ID #1977

With regard to using the location of signals as AT or NEAR the N-terminus, what rule would be applied to this question? "if the first signal presented is located at a position other than the N-terminus" does this mean that the signal is located NEAR the N-terminus or that the signal is located even closer to the C-terminus?


When I say a position other than the N-terminus, it doesn't tell you where it actually is other than stating that it's NOT the first "X" amino acids in the protein. In theory, this working definition means it could be near the C-terminus, but in reality, if it's not AT the N-terminus, it will probably be pretty close to it. Also note that this question (and my answer) refer only to the first signal presented -- other signals can and do come throughout the protein.

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