Mitochondria

ID #1204

Regarding mitochondrial proteins entering the cytoplasm, I was a bit confused. I have written down that as Tom opens the chaperone Hsp70 is peeled. Then, after that though, it appears that a different Hsp70 attaches so that it can enter Tim.


Actually, this is not the case. You don't need a second set of chaperones to get you through Tom and Tim, you need that second set to get you from the matrix side of Tim to the chaperonin complex.  The chaperonin itself is a complex of 14 different (but identical) polypeptide chains, each of which is an individual Hsp60 molecule.

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