Mutations

ID #1825

Is it a coincidence that there are palindromic sequences in DNA ? Are these palindromic sequences conserved consensus sequences?


With palindromes like the 5'-3' sequence GATC, they usually exist as sites to be recognized by some other molecule. We've seen how a specific type of methylase recognizes this sequence, and other palindromes can be recognized by other molecules.

To be conserved, you have to be similar in sequence. Palindromes have a similarity -- they read the same on both strands in a given direction -- but they are not similar in sequence. GATC, for example, is much different than GGGCCC, but they're both palindromes. So no, these wouldn't be conserved regions.

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