The Nucleus and its Functional Domains

ID #2130

Is the nucleus organized such that certain chromosomes only occupy a certain area, and never another area except when brought into the interchromasomal space for replication or transcription?

In biology, one has to have a very good reason to use the word never, so I don't think I'd go so far as to say that chromosomes NEVER occupy a part of some other chromosome's territory. But since we're keeping things relatively simple in this course, it's ok to think of it that way. The nucleolus exists because regions of several different chromosomes have been collected together to have their rRNA genes transcribed. So this would be an example of an instance where (regions of) chromosomes are brought out of their own territories, but not into an interchromosomal territory per se.

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