Transcription and RNA Processing

ID #2408

I was just curious as to what the two step process would be for creating the phosphate bridge. You would bring in the methylated guanine and then covalently bond it to the free 5' phosphate?

An unmodified guanosine (GTP) is first added to the 5' terminal nucleotide in the mRNA. (One of the molecules, either the GTP or the first nucleotide in the mRNA, loses one phosphate and the other molecule loses two. This results in the 5'-5' triphosphate bridge). Next, methyl groups are added to the GTP as well as the first nucleotide in the mRNA. 

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