Transcription and RNA Processing

ID #2061

I have in my notes that eukaryotes don't have multiple proteins per mRNA, so they are monocistronic, but then I also have in my notes that the poly A tail aids in allowing multiple proteins to be efficiently made from a signle eukaryotic mRNA.


Believe it or not, these are not contradictory statements. But what you need to clarify is that when we're talking about polysomes, we're referring to multiple copies of the SAME protein being made. Polycistronic mRNAs have completely different protein coding regions in them, while mature monocistronic mRNAs will only ever have one particular protein product made from it.

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