Transcription and RNA Processing

ID #2036

When do transcription/translation happen in relation to DNA replication? Is replication a part of interphase?

Yes, for eukaryotes which have a nucleus and therefore have to do nuclear division (mitosis), DNA replication occurs during a specific period of interphase. Protein synthesis, which includes transcription and translation, occurs throughout interphase. But neither replication nor protein synthesis occur during M-phase. The DNA is simply too condensed to access for either replication or transcription.


For prokaryotes, no nucleus means no mitosis, and these cells don't have what we would call a cell cycle. They pretty much just start replicating their DNA as soon as they are produced from the prior division, grow and metabolize until the DNA is replicated, and then divide again. Fairly simple!

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