Sushant Bangru

Biochemistry Graduate Student


School of Molecular Cell Biology

B.S. Biological Sciences - Indian Institute of Science (IISC), Bangalore

Started in Lab: December 2015


Email:bangru2@illinois.edu


Publications

Bangru S and Kalsotra A (2016) Advances in analyzing RNA diversity in eukaryotic transcriptomes: peering through the Omics lens.
F1000Research. 5:2668 doi: 10.12688/f1000research.9511.1




Biography

Hello, my name is Sushant and I am a graduate student in the department of Biochemistry. For the longest time in high school I wanted to study Physics. And so, I did my undergraduate studies at the IISC, Bangalore majoring in Biological Sciences (surprised? ...I am too!!). The first time I learnt biology I got so excited, I couldn’t look back and well, here I am. Anyway, I wanted to get into research and I ended up working on a mixed bag of topics ranging from information theory to bacterial methylation. For my undergraduate thesis I worked on classical restriction-modification systems from Helicobacter pylori, and tried to elucidate the biochemistry of methylation of these proteins, and their role in bacterial virulence.

When I first came to UIUC, having worked majorly with DNA and DNA binding proteins, I wasn’t really thinking about working in RNA biology. But, I wanted to work on questions in biology which required both computational and molecular biology methods. I got really interested in alternative splicing and how the cell makes multiple proteins from the same starting transcript and its interplay with spatiotemporal control in cells, after hearing about the research taking place in the Kalsotra lab. It provided the right blend of things I was looking for and I believe there are a lot of questions in the field still unanswered. For my graduate thesis, I will be working on the ESRP2 splicing factor and its role in liver development. I will be using knockout mice models, RNA sequencing among other techniques to investigate this system. In my spare time I like to listen to music, and I recently started learning the piano. Though my favorite pastime is spending hours on Wikipedia reading about random topics from earthly things to exoplanets.