TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000248437 | hsapiens_gene_ensembl | Tubulin
alpha-4A chain (Tubulin alpha-1 chain) (Alpha-tubulin 1)
(Testis-specific alpha-tubulin) (Tubulin H2-alpha).
[Source:Uniprot/SWISSPROT;Acc:P68366]
(448 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
00276 688 0.0
12457 449 e-131
06360 330 6e-91
03702 278 3e-75
17215 254 7e-68
16482 213 1e-55
13181 187 5e-48
04882 176 2e-44
05902 137 7e-33
25015 114 1e-25
39157 91 6e-19
28905 91 8e-19
31457 88 6e-18
13964 33 0.17
26569 32 0.55
06591 30 2.7
18555 28 6.1
>00276
Length = 1330
Score = 688 bits (1776), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 328/360 (91%), Positives = 338/360 (93%)
Frame = -3
Query: 80 NGPYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDPVLDRIRKLSDQCTGLQGFLVFH 139
G YRQL PEQL+TGKEDAANNYARGHYTIGKE++D VLDRIRKL+DQCTGLQGFL+FH
Sbjct: 1328 TGTYRQL-SPEQLVTGKEDAANNYARGHYTIGKELVDLVLDRIRKLADQCTGLQGFLIFH 1152
Query: 140 XXXXXXXXXXXXLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSD 199
L MERLSVDYGKKSKLEF IYPAPQVSTAVVEPYNSILTTHTTLEHSD
Sbjct: 1151 SFGGGTGSGFTSLXMERLSVDYGKKSKLEFXIYPAPQVSTAVVEPYNSILTTHTTLEHSD 972
Query: 200 CAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNL 259
CAFMVDNEAIYDICRRNLDIERPTYTNLNRLI QIVSSITASLRFDGALNVDLTEFQTNL
Sbjct: 971 CAFMVDNEAIYDICRRNLDIERPTYTNLNRLIXQIVSSITASLRFDGALNVDLTEFQTNL 792
Query: 260 VPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLY 319
VPYPRIHFPLATYAPVISAEKAYHEQL VAEITNACFEPANQ+VKCDPRHGKYMACC+LY
Sbjct: 791 VPYPRIHFPLATYAPVISAEKAYHEQLXVAEITNACFEPANQLVKCDPRHGKYMACCMLY 612
Query: 320 RGDVVPKDVNAAIAAIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLS 379
RGDVVPKDVNAAIA IKTKR+IQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLS
Sbjct: 611 RGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLS 432
Query: 380 NTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGIDS 439
NTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEARED+AALEKDYEEVG+DS
Sbjct: 431 NTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGVDS 252
>12457
Length = 781
Score = 449 bits (1155), Expect(2) = e-131, Method: Compositional matrix adjust.
Identities = 214/239 (89%), Positives = 222/239 (92%)
Frame = -1
Query: 67 FVDLEPTVIDEIRNGPYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDPVLDRIRKLS 126
VDLEPTV+DE+R G YRQLFHPEQL+TGKEDAANNYARGHYTIGKEI+D VLDRIRKL+
Sbjct: 718 LVDLEPTVVDEVRTGTYRQLFHPEQLVTGKEDAANNYARGHYTIGKEIVDLVLDRIRKLA 539
Query: 127 DQCTGLQGFLVFHXXXXXXXXXXXXLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYN 186
DQCTGLQGFL+FH LLMERLSVDYGKKSKLEF+IYPAPQVSTAVVEPYN
Sbjct: 538 DQCTGLQGFLIFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFAIYPAPQVSTAVVEPYN 359
Query: 187 SILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDG 246
SILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLI QIVSSITASLRFDG
Sbjct: 358 SILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDG 179
Query: 247 ALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKC 305
ALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQL+VAEITNACFEPANQMVKC
Sbjct: 178 ALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLTVAEITNACFEPANQMVKC 2
Score = 37.4 bits (85), Expect(2) = e-131, Method: Compositional matrix adjust.
Identities = 19/28 (67%), Positives = 19/28 (67%)
Frame = -2
Query: 45 GDDSFTTFFCETGAGKHVPRAVFVDLEP 72
GDDSFT ETGAGKHVPRAV P
Sbjct: 780 GDDSFTPL-SETGAGKHVPRAVSSXXSP 700
>06360
Length = 1896
Score = 330 bits (847), Expect = 6e-91, Method: Compositional matrix adjust.
Identities = 154/178 (86%), Positives = 161/178 (90%)
Frame = -1
Query: 1 MRECISVHVGQAGVQMGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFTTFFCETGAGK 60
MRECISVHVGQAGVQMGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSF TFF ETGAGK
Sbjct: 1710 MRECISVHVGQAGVQMGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGK 1531
Query: 61 HVPRAVFVDLEPTVIDEIRNGPYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDPVLD 120
HVPRAVFVDLEPTV+DE+R G YRQLFHPEQL+TGKEDAANNYARGHYTIGKEI+D VLD
Sbjct: 1530 HVPRAVFVDLEPTVVDEVRTGTYRQLFHPEQLVTGKEDAANNYARGHYTIGKEIVDLVLD 1351
Query: 121 RIRKLSDQCTGLQGFLVFHXXXXXXXXXXXXLLMERLSVDYGKKSKLEFSIYPAPQVS 178
RIRKL+DQCTGLQGFL+FH LLMERLSVDYGKKSKLEF+IYPAPQVS
Sbjct: 1350 RIRKLADQCTGLQGFLIFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFAIYPAPQVS 1177
>03702
Length = 1932
Score = 278 bits (711), Expect = 3e-75, Method: Compositional matrix adjust.
Identities = 138/155 (89%), Positives = 142/155 (91%)
Frame = +1
Query: 153 LMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDI 212
L ERLSVDYGKKSKLEF+IYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDI
Sbjct: 1453 L*ERLSVDYGKKSKLEFAIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDI 1632
Query: 213 CRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATY 272
CRRNLDIERP YTNLNRLI QIVSSITASLRFDGALNVDLTEFQTNLVP P P
Sbjct: 1633 CRRNLDIERPXYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVPTPH-PLPPGHL 1809
Query: 273 APVISAEKAYHEQLSVAEITNACFEPANQMVKCDP 307
PVISAEKAYHEQL+VAE+TNACFEPANQ+VKCDP
Sbjct: 1810 CPVISAEKAYHEQLTVAEVTNACFEPANQLVKCDP 1914
>17215
Length = 632
Score = 254 bits (648), Expect = 7e-68, Method: Compositional matrix adjust.
Identities = 118/123 (95%), Positives = 122/123 (99%)
Frame = +3
Query: 317 LLYRGDVVPKDVNAAIAAIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVC 376
+LYRGDVVPKDVNAAIA IKTKR+IQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVC
Sbjct: 3 MLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVC 182
Query: 377 MLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVG 436
MLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEARED+AALEKDYEEVG
Sbjct: 183 MLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVG 362
Query: 437 IDS 439
+DS
Sbjct: 363 VDS 371
>16482
Length = 837
Score = 213 bits (542), Expect = 1e-55, Method: Compositional matrix adjust.
Identities = 103/248 (41%), Positives = 149/248 (60%)
Frame = +1
Query: 1 MRECISVHVGQAGVQMGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFTTFFCETGAGK 60
MRE + + GQ G Q+G WE+ EHGI P G D + + ++ E GK
Sbjct: 100 MREIVHMQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQ--LERINVYYNEATGGK 273
Query: 61 HVPRAVFVDLEPTVIDEIRNGPYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDPVLD 120
+VPRAV VDLEP +D +R+GP+ Q+F P+ + G+ A NN+A+GHYT G E++D VLD
Sbjct: 274 YVPRAVLVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLD 453
Query: 121 RIRKLSDQCTGLQGFLVFHXXXXXXXXXXXXLLMERLSVDYGKKSKLEFSIYPAPQVSTA 180
+RK ++ C LQGF + H LL+ ++ +Y + FS+ P+P+VS
Sbjct: 454 VVRKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDT 633
Query: 181 VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITA 240
VVEPYN+ L+ H +E++D + +DNEA+YDIC R L + PTY +LN L+S +S +T
Sbjct: 634 VVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTT 813
Query: 241 SLRFDGAL 248
LRF G L
Sbjct: 814 CLRFPGQL 837
>13181
Length = 1092
Score = 187 bits (476), Expect = 5e-48, Method: Compositional matrix adjust.
Identities = 85/225 (37%), Positives = 131/225 (58%)
Frame = -3
Query: 210 YDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPL 269
YDIC R L + PTY +LN L+S +S +T LRF G LN DL + N+VP+PR+HF +
Sbjct: 1090 YDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFM 911
Query: 270 ATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVN 329
+AP+ S + L+V E+T F+ N M CDPRHG+Y+ ++RG + K+V+
Sbjct: 910 PGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAMFRGRMSMKEVD 731
Query: 330 AAIAAIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWA 389
+ ++ K S FV+W P K + PP ++ + + N+TAI E +
Sbjct: 730 EQMLNVQNKNSSYFVEWIPNNVKTAVCDIPP--------RGLKMSATFVGNSTAIQELFK 575
Query: 390 RLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEE 434
R+ +F M+ ++AF+HWY GEGM+E EF+EA +M L +Y++
Sbjct: 574 RISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQ 440
>04882
Length = 1136
Score = 176 bits (446), Expect = 2e-44, Method: Compositional matrix adjust.
Identities = 79/216 (36%), Positives = 125/216 (57%)
Frame = +2
Query: 219 IERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISA 278
+ PTY +LN L+S +S +T LRF G LN DL + N+VP+PR+HF + +AP+ S
Sbjct: 314 VHTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSR 493
Query: 279 EKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIAAIKTK 338
+ L+V E+T F+ N M CDPRHG+Y+ ++RG + K+V+ + ++ K
Sbjct: 494 GSQQYRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNK 673
Query: 339 RSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLM 398
S FV+W P K + PP ++ + + N+TAI E + R+ +F M
Sbjct: 674 NSSYFVEWIPNNVKTAVCDIPPR--------GLKMSATFIGNSTAIQELFKRISEQFTAM 829
Query: 399 YAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEE 434
+ ++AF+HWY GEGM+E EF+EA +M L +Y++
Sbjct: 830 FRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQ 937
>05902
Length = 1127
Score = 137 bits (346), Expect = 7e-33, Method: Compositional matrix adjust.
Identities = 82/290 (28%), Positives = 160/290 (55%), Gaps = 9/290 (3%)
Frame = +2
Query: 153 LMERLSVDYGKKSKLEFSIYP-APQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYD 211
L+E+L+ + KK +S++P ++S VV+PYNS+LT +++DC ++DN A+
Sbjct: 65 LLEKLNDRFPKKLIQTYSVFPNVDEISDVVVQPYNSLLTLKRLTQNADCVVVLDNTALNR 244
Query: 212 ICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLAT 271
I L I+ PT+ +N+L+S ++S+ T +LR+ G +N DL +L+P PR+HF +
Sbjct: 245 IAADRLHIDTPTFAQVNQLVSTVMSTSTTTLRYPGYMNNDLIGLIASLIPTPRLHFLMTG 424
Query: 272 YAPVIS-AEKAYHEQLSVAEITNACFEPANQMVKCDPRHGK----YMACCLLYRGDVVPK 326
Y P+ + ++ A + +V ++ +P N MV P H + Y++ + +G+V P
Sbjct: 425 YTPLTTDSQVANVRKTTVLDVMRRLLQPKNMMVST-PVHRQANHCYISILNIIQGEVDPT 601
Query: 327 DVNAAIAAIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAE 386
V+ ++ I+ ++ QF+ W P +V ++ + P V ++ + ML+N T+I+
Sbjct: 602 QVHKSLQRIRERKLAQFIPWGPASIQVALSRKSPYVQTAHRVSGL-----MLANHTSISH 766
Query: 387 AWARLDHKFDLMYAKRAFVHWYVGEGMEE---GEFSEAREDMAALEKDYE 433
+ R+ ++D + + AF+ + E + + EF +RE + L +Y+
Sbjct: 767 LFERILRQYDKLRKREAFMDQFKKEAIFKDNLDEFDNSREALQLLVDEYQ 916
>25015
Length = 458
Score = 114 bits (284), Expect = 1e-25, Method: Compositional matrix adjust.
Identities = 52/119 (43%), Positives = 74/119 (62%)
Frame = -3
Query: 21 WELYCLEHGIQPDGQMPSDKTIGGGDDSFTTFFCETGAGKHVPRAVFVDLEPTVIDEIRN 80
WE+ EHGI P G D + + ++ E GK+VPRAV VDLEP +D +R+
Sbjct: 360 WEVISDEHGIDPTGTYHGDSDLQ--LERINVYYNEATGGKYVPRAVLVDLEPGTMDSVRS 187
Query: 81 GPYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDPVLDRIRKLSDQCTGLQGFLVFH 139
GP+ Q+F P+ + G+ A NN+A+GHYT G E++D VLD +RK ++ C LQGF + H
Sbjct: 186 GPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQLTH 10
>39157
Length = 488
Score = 91.3 bits (225), Expect = 6e-19, Method: Compositional matrix adjust.
Identities = 49/127 (38%), Positives = 72/127 (56%), Gaps = 3/127 (2%)
Frame = -1
Query: 1 MRECISVHVGQAGVQMGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFTTFFCETGAGK 60
MRE + + GQ G Q+G WE+ EHGI P G D + + ++ E GK
Sbjct: 443 MREIVHLQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQ--LERINVYYNEATGGK 270
Query: 61 HVPRAVFVDLEPTVIDEIRNG-PYR-QLFHPEQLITGKEDAANNYARGHYTI-GKEIIDP 117
+VPRAV VDLEP +D +R+G P+ ++F P+ + G+ A NN+ + T G E++D
Sbjct: 269 YVPRAVLVDLEPGTMDSVRSGSPFGPKIFRPDNFVFGQSGAGNNWGQKDTTQRGAELVDS 90
Query: 118 VLDRIRK 124
VLD +RK
Sbjct: 89 VLDVVRK 69
>28905
Length = 425
Score = 91.3 bits (225), Expect = 8e-19, Method: Composition-based stats.
Identities = 37/103 (35%), Positives = 59/103 (57%)
Frame = -1
Query: 258 NLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCL 317
N+VP+PR+HF + +AP+ S + L+V E+T F+ N M CDPRHG+Y+
Sbjct: 380 NMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAA 201
Query: 318 LYRGDVVPKDVNAAIAAIKTKRSIQFVDWCPTGFKVGINYQPP 360
++RG + K+V+ + ++ K S FV+W P K + PP
Sbjct: 200 MFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPP 72
>31457
Length = 1530
Score = 88.2 bits (217), Expect = 6e-18, Method: Compositional matrix adjust.
Identities = 40/124 (32%), Positives = 69/124 (55%)
Frame = +3
Query: 311 KYMACCLLYRGDVVPKDVNAAIAAIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAK 370
KY+ ++RG + K+V+ + ++ K S FV+W P K + PP
Sbjct: 234 KYLTVAAMFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPR--------G 389
Query: 371 VQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEK 430
++ + + N+TAI E + R+ +F M+ ++AF+HWY GEGM+E EF+EA +M L
Sbjct: 390 LKMSSTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS 569
Query: 431 DYEE 434
+Y++
Sbjct: 570 EYQQ 581
>13964
Length = 528
Score = 33.5 bits (75), Expect = 0.17, Method: Compositional matrix adjust.
Identities = 14/16 (87%), Positives = 16/16 (100%)
Frame = +2
Query: 424 DMAALEKDYEEVGIDS 439
D+AALEKDYEEVG+DS
Sbjct: 230 DLAALEKDYEEVGVDS 277
>26569
Length = 1180
Score = 32.0 bits (71), Expect = 0.55, Method: Compositional matrix adjust.
Identities = 20/62 (32%), Positives = 26/62 (41%)
Frame = +1
Query: 373 RAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDY 432
R V +N A +E W + KF A+ HW G+G E + S AR L D
Sbjct: 481 RGVNRPANYCAGSETWTQRKKKFSNWNAR----HWKRGKGKERRKISLARAGGVGLAVDT 648
Query: 433 EE 434
E
Sbjct: 649 SE 654
>06591
Length = 978
Score = 29.6 bits (65), Expect = 2.7, Method: Compositional matrix adjust.
Identities = 19/57 (33%), Positives = 24/57 (42%)
Frame = -2
Query: 320 RGDVVPKDVNAAIAAIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVC 376
RG VP + T S DWCP G + G+ YQ T D+A Q +C
Sbjct: 767 RGSCVPSE---------TSLSTPVTDWCPQGDQPGVVYQNLTCA---DVATSQPWLC 633
>18555
Length = 596
Score = 28.5 bits (62), Expect = 6.1, Method: Compositional matrix adjust.
Identities = 16/48 (33%), Positives = 26/48 (54%)
Frame = -1
Query: 232 SQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAE 279
+QI S S + AL +D F + + P+++FPL+ PV+SA
Sbjct: 344 NQIFS*S*KSFCYSLALTIDKKHFNKDRLLKPKVNFPLS*GQPVLSAS 201
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000253339 | hsapiens_gene_ensembl |
Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor
suppressor homolog 1) (WARTS protein kinase) (h-warts).
[Source:Uniprot/SWISSPROT;Acc:O95835]
(1130 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
03240 660 0.0
30755 119 8e-27
18484 108 1e-23
27405 107 4e-23
31885 102 9e-22
12721 100 5e-21
00486 98 2e-20
00300 91 4e-18
14420 89 8e-18
18921 83 7e-16
09606 82 1e-15
26560 80 5e-15
13592 78 2e-14
18663 77 3e-14
17975 73 7e-13
01707 73 8e-13
26156 62 2e-12
15910 66 9e-11
21079 62 1e-09
13066 60 3e-09
16708 60 4e-09
01392 59 8e-09
01756 59 1e-08
25019 59 2e-08
13212 59 2e-08
14126 57 3e-08
01060 57 3e-08
27546 57 4e-08
19094 55 2e-07
17932 54 3e-07
01966 53 6e-07
21433 53 9e-07
02638 52 1e-06
29581 52 1e-06
26711 52 1e-06
37602 52 1e-06
17722 51 2e-06
03508 51 3e-06
06405 50 4e-06
18401 50 5e-06
12786 50 6e-06
11185 49 1e-05
04591 48 2e-05
33586 47 3e-05
00715 47 4e-05
20152 47 4e-05
28638 47 5e-05
21808 47 6e-05
04138 45 1e-04
29590 44 3e-04
32957 44 5e-04
14116 43 7e-04
19301 43 8e-04
11780 42 0.001
32359 33 0.001
17516 42 0.001
28157 41 0.003
14477 41 0.003
19761 40 0.005
04852 40 0.007
18481 40 0.007
20640 39 0.013
01718 39 0.014
09007 38 0.020
07833 38 0.020
00638 38 0.022
07836 38 0.025
07291 37 0.052
07940 37 0.065
26009 35 0.18
00392 35 0.20
31489 35 0.23
12672 34 0.33
13078 34 0.42
29360 33 0.47
18996 33 0.47
11404 33 0.57
37063 32 1.0
17300 32 1.2
03275 32 1.4
01106 31 2.3
31120 31 2.9
17637 31 3.3
36481 30 5.9
21800 30 6.9
>03240
Length = 1683
Score = 660 bits (1703), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 341/504 (67%), Positives = 392/504 (77%), Gaps = 5/504 (0%)
Frame = -3
Query: 592 ESEKSYENVDSGDKEKKQITTSPITVRK---NKKDEERRESRIQSYSPQAFKFFMEQHVE 648
E+ S E SG +K SP+ RK ++D+ RR++++++YSPQAFKF+MEQHVE
Sbjct: 1633 ETVSSSETGASGGGGEKHRCMSPMPQRKPEARERDKLRRDTKVRNYSPQAFKFYMEQHVE 1454
Query: 649 NVLKSHQQRLHRKKQLENEMMRVGLSQDAQDQMRKMLCQKESNYIRLKRAKMDKSMFVKI 708
NVLK HQQRL R+ QLENEM +V LS++A QMR+ML QKESNYIRLKRAKMDK MF KI
Sbjct: 1453 NVLKIHQQRLRRRTQLENEMAKVKLSEEAARQMRRMLHQKESNYIRLKRAKMDKCMFEKI 1274
Query: 709 KTLGIGAFGEVCLARKVDTKALYATKTLRKKDVLLRNQVAHVKAERDILAEADNEWVVRL 768
KTLG+GAFGEV L RK DT LYA KTLRK DVL RNQVAHVKAERDILAEADNEWVV+L
Sbjct: 1273 KTLGVGAFGEVSLCRKNDTGMLYAMKTLRKSDVLKRNQVAHVKAERDILAEADNEWVVKL 1094
Query: 769 YYSFQDKDNLYFVMDYIPGGDMMSLLIRMGIFPESLARFYIAELTCAVESVHKMGFIHRD 828
YYSFQD + LYFVMDY+PGGD+M LLIRM I E LARFY+AEL A+ESVH+MGFIHRD
Sbjct: 1093 YYSFQDHNYLYFVMDYVPGGDLMGLLIRMEILDEPLARFYVAELVQAIESVHRMGFIHRD 914
Query: 829 IKPDNILIDRDGHIKLTDFGLCTGFRWTHDSKYYQ-SGDHPRQDSMDFSNEWGDPSSCRC 887
IKPDNILIDR+GHIKLTDFGLCTGFRWTH+SKYYQ G H RQDSM+ + + C
Sbjct: 913 IKPDNILIDRNGHIKLTDFGLCTGFRWTHNSKYYQRDGTHARQDSMEVKCQLDEQCQCEI 734
Query: 888 GDRLKPLERRAARQHQRCLAHSLVGTPNYIAPEVLLRT-GYTQLCDWWSVGVILFEMLVG 946
LKPLERR R+ QRCLAHSLVGTPNYIAPEVL R GYT +CDWWSVGVILFEMLVG
Sbjct: 733 ---LKPLERRRKRE-QRCLAHSLVGTPNYIAPEVLSRLGGYTSVCDWWSVGVILFEMLVG 566
Query: 947 QPPFLAQTPLETQMKVINWQTSLHIPPQAKLSPEASDLIIKLCRGPEDRLGKNGADEIKA 1006
PPF A TP ETQ KVINW+ L IP ++ LS A DLI++LC G +DRLG NGA EIK
Sbjct: 565 HPPFYANTPAETQYKVINWKDMLKIPRESNLSQPAKDLILRLCCGSDDRLGLNGAGEIKT 386
Query: 1007 HPFFKTIDFSSDLRQQSASYIPKITHPTDTSNFDPVDPDKLWSDDNEEENVNDTLNGWYK 1066
H FF ++F + LR+Q Y+P I + TDTSNFDPVDPDKL + D+EE + L +
Sbjct: 385 HMFFAGVNFET-LRKQQPPYVPNIRYATDTSNFDPVDPDKLRNSDSEENKKVEKL----E 221
Query: 1067 NGKHPEHAFYEFTFRRFFDDNGYP 1090
NGKHPEHAF+EFTFRRFFDD G+P
Sbjct: 220 NGKHPEHAFFEFTFRRFFDDGGHP 149
>30755
Length = 1137
Score = 119 bits (298), Expect = 8e-27, Method: Compositional matrix adjust.
Identities = 83/248 (33%), Positives = 122/248 (49%), Gaps = 6/248 (2%)
Frame = +2
Query: 799 IFPESLARFYIAELTCAVESVHKMGFIHRDIKPDNILIDRDGHIKLTDFGLCTGFRWTHD 858
IF E RFY AE+ A+ +H G I+RD+K +N+L+D+DGHIK+ DFGLC
Sbjct: 20 IFTEERTRFYGAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLC-------- 175
Query: 859 SKYYQSGDHPRQDSMDFSNEWGDPSSCRCGDRLKPLERRAARQHQRCLAHSLVGTPNYIA 918
++D +G + CG TP Y+A
Sbjct: 176 ----------KEDIT-----YGRTTKTFCG------------------------TPEYLA 238
Query: 919 PEVLLRTGYTQLCDWWSVGVILFEMLVGQPPFLAQ--TPLETQMKVINWQTSLHIPPQAK 976
PEVL Y + DWW GV+++EM+ G+ PF + L T + V + + +I +AK
Sbjct: 239 PEVLDDNDYGRAVDWWGTGVVMYEMICGRLPFYNRDHDVLFTLILVEDVKFPRNITDEAK 418
Query: 977 LSPEASDLIIKLCRGPEDRLGKNGAD--EIKAHPFFKTIDFSSDLRQQSAS--YIPKITH 1032
S L L + P +RLG D EI+AHPFF +I++ +DL Q+ + + P++T
Sbjct: 419 -----SLLSGLLAKDPRNRLGGGQDDVKEIQAHPFFASINW-TDLVQKKITPPFKPQVTS 580
Query: 1033 PTDTSNFD 1040
TDT FD
Sbjct: 581 DTDTRYFD 604
>18484
Length = 635
Score = 108 bits (270), Expect = 1e-23, Method: Composition-based stats.
Identities = 69/214 (32%), Positives = 100/214 (46%), Gaps = 5/214 (2%)
Frame = +1
Query: 789 DMMSLLIRMGIFPESLARFYIAELTCAVESVHKMGFIHRDIKPDNILIDRDGHIKLTDFG 848
D+M + + G F E +A FY AE+ + +H G I+RD+K DN+++D +GHIK+ DFG
Sbjct: 1 DLMYRIQQEGKFKEPVAAFYAAEIAVGLFFLHDQGIIYRDLKLDNVMLDSEGHIKIADFG 180
Query: 849 LCTGFRWTHDSKYYQSGDHPRQDSMDFSNEWGDPSSCRCGDRLKPLERRAARQHQRCLAH 908
+C K +GD
Sbjct: 181 MC---------KEGMTGD--------------------------------------ATTR 219
Query: 909 SLVGTPNYIAPEVLLRTGYTQLCDWWSVGVILFEMLVGQPPFLAQTPLETQMKVINWQTS 968
+ GTP+YIAPE++L Y++ DWW+ GV+LFEML GQPPF + E + + S
Sbjct: 220 TFCGTPDYIAPEIVLYQPYSKSVDWWAYGVLLFEMLAGQPPFDGEDEDELFSSITDHNVS 399
Query: 969 LHIPPQAKLSPEASDLIIKLCRG-----PEDRLG 997
P+A +S EA + LC+G P RLG
Sbjct: 400 Y---PKA-MSREA----VSLCKGLLMKNPTKRLG 477
>27405
Length = 532
Score = 107 bits (266), Expect = 4e-23, Method: Composition-based stats.
Identities = 69/225 (30%), Positives = 106/225 (47%), Gaps = 5/225 (2%)
Frame = -3
Query: 715 AFGEVCLARKVDTKALYATKTLRKKDVLLRNQVAHVKAERDILAEAD----NEWVVRLYY 770
FGEV RK DT +YA K L KK + ++ ER +L+ + ++V + Y
Sbjct: 530 GFGEVYGCRKADTGKMYAMKCLDKKRIKMKGGETLALNERIMLSLVSTGEGSPFIVCMTY 351
Query: 771 SFQDKDNLYFVMDYIPGGDMMSLLIRMGIFPESLARFYIAELTCAVESVHKMGFIHRDIK 830
+FQ + L F++D + GGD+ L + G+F E RFY AE+ +E +H ++RD+K
Sbjct: 350 AFQTPEKLCFILDLMNGGDLHYHLSQHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLK 171
Query: 831 PDNILIDRDGHIKLTDFGLCTGFRWTHDSKYYQSGDHPRQDSMDFSNEWGDPSSCRCGDR 890
P NIL+D +GH++++D GL + DFS +
Sbjct: 170 PANILLDENGHVRISDLGL----------------------ACDFSKK------------ 93
Query: 891 LKPLERRAARQHQRCLAHSLVGTPNYIAPEVLLR-TGYTQLCDWW 934
KP H+ VGT Y+APEVL++ Y DW+
Sbjct: 92 -KP--------------HASVGTHGYMAPEVLMKGQAYDSSADWF 3
>31885
Length = 529
Score = 102 bits (254), Expect = 9e-22, Method: Composition-based stats.
Identities = 64/201 (31%), Positives = 94/201 (46%), Gaps = 5/201 (2%)
Frame = -2
Query: 755 DILAEADNEWVVRLYYSFQDKDNLYFVMDYIPGGDMMSLLIRMGIFPESLARFYIAELTC 814
D+L D+ ++V L+Y+FQD+++L+ V+D GGD+ + + F E +FY+ +L
Sbjct: 516 DMLTRLDHPFLVNLWYAFQDEEDLFMVVDLFLGGDLRYHMQQEVSFREDCVKFYLCQLAL 337
Query: 815 AVESVHKMGFIHRDIKPDNILIDRDGHIKLTDFGLCTGFRWTHDSKYYQSGDHPRQDSMD 874
++ + +HRDIKPDNIL+D GH +TDF + T
Sbjct: 336 VLDYLRSQKIVHRDIKPDNILLDEQGHCHVTDFNIAT----------------------- 226
Query: 875 FSNEWGDPSSCRCGDRLKPLERRAARQHQRCLAHSLVGTPNYIAPEVL-----LRTGYTQ 929
+L+ E LA S GT Y+APEV R GY
Sbjct: 225 ---------------QLEDDE----------LATSTSGTRPYMAPEVYGVAINERRGYGF 121
Query: 930 LCDWWSVGVILFEMLVGQPPF 950
DWWS+GV LFE+L + PF
Sbjct: 120 PVDWWSLGVSLFELLKKRRPF 58
>12721
Length = 821
Score = 100 bits (248), Expect = 5e-21, Method: Compositional matrix adjust.
Identities = 87/299 (29%), Positives = 135/299 (45%), Gaps = 8/299 (2%)
Frame = +1
Query: 705 FVKIKTLGIGAFGEVCLARKVDTKALYATKT-LRK--KDVLLRNQVAHVKAERDILAEAD 761
F+KI G G+ G VC+A D + + K LRK + LL N+V ++ +
Sbjct: 103 FMKI---GEGSTGIVCIATSRDGRQMAVKKMDLRKQQRRELLFNEVV-------VMRDYH 252
Query: 762 NEWVVRLYYSFQDKDNLYFVMDYIPGGDMMSLLIRMGIFPESLARFYIAELTCAVESVHK 821
+ +V +Y S+ D L+ VM+++ GG + ++ + +A A L A+ +H
Sbjct: 253 HPNIVEMYNSYLVNDELWVVMEFMEGGALTDIVTNNRMDEVQIATVCRACLK-ALAFLHA 429
Query: 822 MGFIHRDIKPDNILIDRDGHIKLTDFGLCTGFRWTHDSKYYQSGDHPRQDSMDFSNEWGD 881
G IHRDIK D+IL+ DG +KL DFG C + T D
Sbjct: 430 NGVIHRDIKSDSILLSHDGKVKLXDFGFCA--QVTQD----------------------- 534
Query: 882 PSSCRCGDRLKPLERRAARQHQRCLAHSLVGTPNYIAPEVLLRTGYTQLCDWWSVGVILF 941
L++R SLVGTP ++APEV+ R Y D WS+G+++
Sbjct: 535 ------------LQKRK----------SLVGTPYWMAPEVISRLPYGPEVDIWSLGIMVM 648
Query: 942 EMLVGQPPFLAQTPLETQMKVINWQTSLHIPPQA----KLSPEASDLIIK-LCRGPEDR 995
EM+ +PPF + PL+ ++ + PP+ K+SP I + L R P R
Sbjct: 649 EMIDAEPPFFNEPPLQAMRRIRDMP-----PPKLRNTHKISPRLQGFIDRMLVRDPHQR 810
>00486
Length = 797
Score = 97.8 bits (242), Expect = 2e-20, Method: Compositional matrix adjust.
Identities = 59/165 (35%), Positives = 94/165 (56%), Gaps = 4/165 (2%)
Frame = -2
Query: 906 LAHSLVGTPNYIAPEVLLRTGYTQLCDWWSVGVILFEMLVGQPPFLAQTPLETQMKVINW 965
+ H+ GT Y+APE+L RTG+ + DWWS+G ++++ML G PPF A+ +T K++
Sbjct: 790 VTHTFCGTIEYMAPEILTRTGHGKAVDWWSLGALMYDMLTGSPPFTAENRKKTIDKIL-- 617
Query: 966 QTSLHIPPQAKLSPEASDLIIKLCR-GPEDRLGKNGADE--IKAHPFFKTIDFS-SDLRQ 1021
+ L++PP L+ EA LI KL R P +RLG D IK H FF+ +++ LR+
Sbjct: 616 KGKLNLPPY--LTNEARGLIKKLLRKNPAERLGGGHDDSGPIKDHQFFRNTNWALLALRR 443
Query: 1022 QSASYIPKITHPTDTSNFDPVDPDKLWSDDNEEENVNDTLNGWYK 1066
+ P +T DTS FD + D ++ ++D++N +K
Sbjct: 442 AEPPFRPNVTSDEDTSQFDTKFTRQTPVDSPDDTILSDSINQVFK 308
>00300
Length = 2318
Score = 90.5 bits (223), Expect = 4e-18, Method: Compositional matrix adjust.
Identities = 82/300 (27%), Positives = 129/300 (43%), Gaps = 9/300 (3%)
Frame = -1
Query: 660 RKKQLENEMMRVGLSQDAQDQMRKMLCQ-----KESNY-IRLKRAKMDKSMFVKIKTLGI 713
R++ ++ E+ + +DAQ Q + + + +E +Y I ++R KI G
Sbjct: 1796 RRQHIQEEVKMLERQRDAQLQEKSRIGRVAAKPREPDYRINVRRVNFRWQRGNKI---GE 1626
Query: 714 GAFGEVCLARKVDTKALYATKTLRKKDVLLRNQVAHVKAERDILAEADNEWVVRLYYSFQ 773
G FG+V A + T L A K ++ + L+ Q+ + E I +E +V+ Y
Sbjct: 1625 GQFGKVYTAVNMSTGELMALKEMKFQPNDLQ-QLREMCDEIKIFEGIQHENLVKYYGVEV 1449
Query: 774 DKDNLYFVMDYIPGGDMMSLLIRMGIFPESLARFYIAELTCAVESVHKMGFIHRDIKPDN 833
KD + M+Y G + +MG+ PE L R Y E+ AV +H+ +HRDIK N
Sbjct: 1448 HKDEMLMFMEYCDTGTIEEA-AKMGL-PEYLIRRYTREIVLAVNHLHENSIVHRDIKGAN 1275
Query: 834 ILIDRDGHIKLTDFGLCTGFRWTHDSKYYQSGDHPRQDSMDFSNEWGDPSSCRCGDRLKP 893
I + +GH+KL DFG C +LK
Sbjct: 1274 IFLTSNGHVKLGDFG--------------------------------------CSVKLKS 1209
Query: 894 LERRAARQHQRCLAHSLVGTPNYIAPEVLLRT---GYTQLCDWWSVGVILFEMLVGQPPF 950
H+LVGT Y+APEV + GY + D WS+G ++ EM G+ P+
Sbjct: 1208 HTTMPGE------FHNLVGTTAYMAPEVFTQNDQGGYGRAADIWSLGCVVIEMATGKRPW 1047
>14420
Length = 528
Score = 89.4 bits (220), Expect = 8e-18, Method: Compositional matrix adjust.
Identities = 60/201 (29%), Positives = 92/201 (45%)
Frame = +2
Query: 756 ILAEADNEWVVRLYYSFQDKDNLYFVMDYIPGGDMMSLLIRMGIFPESLARFYIAELTCA 815
++ E N +V S+ + L+ VM+++ GG + ++ + +A E A
Sbjct: 59 VMRENQNPNIVNYLDSYLVGEELWVVMEFLAGGSLTDVVTETCMDEGQIAAV-CRECLQA 235
Query: 816 VESVHKMGFIHRDIKPDNILIDRDGHIKLTDFGLCTGFRWTHDSKYYQSGDHPRQDSMDF 875
+E +H+ IHRDIK DNIL+ DG +KLTDFG C
Sbjct: 236 LEFLHENQVIHRDIKSDNILLGMDGSVKLTDFGFCA------------------------ 343
Query: 876 SNEWGDPSSCRCGDRLKPLERRAARQHQRCLAHSLVGTPNYIAPEVLLRTGYTQLCDWWS 935
+L P Q +R ++VGTP ++APEV+ R Y D WS
Sbjct: 344 --------------QLSP------EQSKR---STMVGTPYWMAPEVVTRKQYGPTVDIWS 454
Query: 936 VGVILFEMLVGQPPFLAQTPL 956
+GV+ EM+ G+PP+L + PL
Sbjct: 455 LGVMCIEMIEGEPPYLNENPL 517
>18921
Length = 697
Score = 82.8 bits (203), Expect = 7e-16, Method: Composition-based stats.
Identities = 65/262 (24%), Positives = 112/262 (42%), Gaps = 3/262 (1%)
Frame = +2
Query: 698 AKMDKSMFVKIKTLGIGAFGEVCLARKVDTKALYATKTLRKKDVLLRNQVAHVKAERDIL 757
A+ + +F + LG G++G V + +T + A K V + + + E I+
Sbjct: 14 ARPPEDVFDILGKLGEGSYGSVFKSLHKETGQVLAIK-----QVPVDTDLQEIIKEISIM 178
Query: 758 AEADNEWVVRLYYSFQDKDNLYFVMDYIPGG---DMMSLLIRMGIFPESLARFYIAELTC 814
+ D++++V+ Y S+ +L+ VM+Y G D+M L + + E Y
Sbjct: 179 QQCDSKYIVKYYGSYFKNTDLWIVMEYCGAGSVSDIMRLRNKTLVEREIATILYYT--LK 352
Query: 815 AVESVHKMGFIHRDIKPDNILIDRDGHIKLTDFGLCTGFRWTHDSKYYQSGDHPRQDSMD 874
+ +H IHRDIK NIL++ +GH KL DFG+
Sbjct: 353 GLXYLHSRRKIHRDIKAGNILLNNEGHAKLADFGV------------------------- 457
Query: 875 FSNEWGDPSSCRCGDRLKPLERRAARQHQRCLAHSLVGTPNYIAPEVLLRTGYTQLCDWW 934
G + +R ++++GTP ++APEV+ GY + D W
Sbjct: 458 ------------AGQLTDTMAKR----------NTVIGTPYWMAPEVIQEIGYDCVADIW 571
Query: 935 SVGVILFEMLVGQPPFLAQTPL 956
S+G+ EM G+PP + + L
Sbjct: 572 SLGITALEMAEGKPPVMETSIL 637
>09606
Length = 1300
Score = 82.0 bits (201), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 53/200 (26%), Positives = 97/200 (48%)
Frame = -3
Query: 765 VVRLYYSFQDKDNLYFVMDYIPGGDMMSLLIRMGIFPESLARFYIAELTCAVESVHKMGF 824
VV+ + ++ ++L+ V++ GG + +L + PE+ R + L + +H +G
Sbjct: 947 VVQFHEWYETSNHLWLVVELCTGGSLADILAQDHHLPETSIRDFGIHLVTGLHYIHSLGI 768
Query: 825 IHRDIKPDNILIDRDGHIKLTDFGLCTGFRWTHDSKYYQSGDHPRQDSMDFSNEWGDPSS 884
+ D++P +L+D G +K DFGL SK G++ + F+
Sbjct: 767 LFHDLRPSKVLLDTSGVLKFADFGL---------SKV--EGENLEELFFKFA-------- 645
Query: 885 CRCGDRLKPLERRAARQHQRCLAHSLVGTPNYIAPEVLLRTGYTQLCDWWSVGVILFEML 944
GD+ ++A + + + S G+P Y+APEV + + D W++G + +EM
Sbjct: 644 -EAGDQWNI---QSAEEMMKQVPTS--GSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMF 483
Query: 945 VGQPPFLAQTPLETQMKVIN 964
G PPFL +T T+ KV+N
Sbjct: 482 SGHPPFLGETYDITKDKVLN 423
>26560
Length = 398
Score = 79.7 bits (195), Expect = 5e-15, Method: Composition-based stats.
Identities = 49/163 (30%), Positives = 76/163 (46%), Gaps = 1/163 (0%)
Frame = -1
Query: 789 DMMSLLIRMGIFPESLARFYIAELTCAVESVHKMGFIHRDIKPDNILIDRDGHIKLTDFG 848
D+ L + G+F E RFY AE+ +E +H ++RD+KP NIL+D +GH++++D G
Sbjct: 398 DLHYHLSQHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLG 219
Query: 849 LCTGFRWTHDSKYYQSGDHPRQDSMDFSNEWGDPSSCRCGDRLKPLERRAARQHQRCLAH 908
L + DFS + +P H
Sbjct: 218 L----------------------ACDFSKK-------------RP--------------H 186
Query: 909 SLVGTPNYIAPEVLLR-TGYTQLCDWWSVGVILFEMLVGQPPF 950
+ VGT Y+APEVL++ Y DW+S G +L+++L G PF
Sbjct: 185 ASVGTHGYMAPEVLMKGQSYDSSADWFSFGCMLYKLLKGHSPF 57
>13592
Length = 980
Score = 77.8 bits (190), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 81/280 (28%), Positives = 119/280 (42%), Gaps = 5/280 (1%)
Frame = +2
Query: 711 LGIGAFGEVCLARKVDTKALYATKTLRKKDVLLRNQVAHVKAERDILAEADNEWVVRLYY 770
+G G FG+V A +T L A K + + R + +V E IL ++ +VR Y
Sbjct: 8 IGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETR-ALKNVAEELKILEGIKHKNLVRYYG 184
Query: 771 SFQDKDNLYFVMDYIPGGDMMSLLIRMGIFPESLARFYIAELTCAVESVHKMGFIHRDIK 830
++ L M+ G + SL+ G PE+L+R + A+L V +HK G +HRDIK
Sbjct: 185 IEVHREELLIFMELCSEGTLESLVELTGGLPEALSRRFTAQLLSGVAELHKHGIVHRDIK 364
Query: 831 PDNILIDRDGHIKLTDFGLCTGFRWTHDSKYYQSGDHPRQDSMDFSNEWGDPSSCRCGDR 890
NI + +D SN S + GD
Sbjct: 365 TANIFL------------------------------------VDGSN------SLKLGDF 418
Query: 891 LKPLERRAARQHQRCLAHSLVGTPNYIAPEVLLRT---GYTQLCDWWSVGVILFEMLVGQ 947
++ +A L VGT Y+APEV +T G+ +L D WSVG ++ EM G+
Sbjct: 419 GSAVKIQAHTTVPGEL-QGYVGTQAYMAPEVFTKTNSDGHGRLADIWSVGCVVVEMASGK 595
Query: 948 PPFLAQTPLETQMKVINWQTSLHIPPQA--KLSPEASDLI 985
P+ AQ Q I ++ + PQA LS E D I
Sbjct: 596 RPW-AQFDSNFQ---IMFKVGMGEKPQAPESLSQEGHDFI 703
>18663
Length = 600
Score = 77.4 bits (189), Expect = 3e-14, Method: Compositional matrix adjust.
Identities = 51/142 (35%), Positives = 76/142 (53%), Gaps = 11/142 (7%)
Frame = +2
Query: 909 SLVGTPNYIAPEVLLRTGYTQLCDWWSVGVILFEMLVGQPPF----LAQTP---LETQMK 961
+ GTPNYIAPE+L Y DWW++GV+L+EML G+ PF ++ P E +
Sbjct: 5 TFCGTPNYIAPEILRGEDYGFSVDWWALGVLLYEMLAGRSPFDIAGASENPDQNTEDYLF 184
Query: 962 VINWQTSLHIPPQAKLSPEASDLIIKLCRGPEDRLG---KNGADEIKAHPFFKTIDFSSD 1018
+ + ++ IP + AS L L + P DRLG ++ +I HPFFK ID+
Sbjct: 185 QVILEKTIRIPRSLSVK-AASVLKGFLNKNPADRLGCHRESAFMDIVNHPFFKVIDWEML 361
Query: 1019 LRQQ-SASYIPKITHPTDTSNF 1039
R+Q S + P++ D +NF
Sbjct: 362 ERKQVSPPFKPRLDSDRDLANF 427
>17975
Length = 449
Score = 72.8 bits (177), Expect = 7e-13, Method: Composition-based stats.
Identities = 47/138 (34%), Positives = 71/138 (51%), Gaps = 2/138 (1%)
Frame = +3
Query: 716 FGEVCLARKVDTKALYATKTLRKKDVLLRNQVAHVKAERDILAEADNEWVVRLYYSFQDK 775
F V LAR V T A K + K L +H+ E + + VVRLY +
Sbjct: 6 FAVVKLARHVFTGEKVAVKVIDKTK-LDEVSRSHLFQEVRCMKLVQHPNVVRLYEVIDTQ 182
Query: 776 DNLYFVMDYIPGGDMMSLLIR-MGIFPESLARFYIAELTCAVESVHKMGFIHRDIKPDNI 834
LY +++ GGDM ++R G E LA+ Y ++ A+ HK+ +HRD+KP+N+
Sbjct: 183 TKLYLILELGDGGDMYDYIMRHSGGLEEKLAKRYFRQIVEAISYCHKLHVVHRDLKPENV 362
Query: 835 L-IDRDGHIKLTDFGLCT 851
+ ++ G +KLTDFG T
Sbjct: 363 VFFEKPGLVKLTDFGFST 416
>01707
Length = 757
Score = 72.8 bits (177), Expect = 8e-13, Method: Composition-based stats.
Identities = 71/254 (27%), Positives = 106/254 (41%), Gaps = 5/254 (1%)
Frame = +1
Query: 699 KMDKSMFVKIKTLGIGAFGEVCLARKVDTKALYATKT-LRKKDVLLRNQVAHVKAERDIL 757
+M+K + KI +G G++G V R +T L A K + +D L ++A E +L
Sbjct: 58 RMEK--YEKIGKIGEGSYGVVFKCRNKETSQLVAIKKFVESEDDPLIKKIA--MREIRML 225
Query: 758 AEADNEWVVRLYYSFQDKDNLYFVMDYIPGGDMMSLLIRMGIFPESLARFYIAELTCAVE 817
+ + +VRL F+ K L+ V DY+ + L PE + + I + AV
Sbjct: 226 KQLKHPNLVRLIEVFRRKKRLHLVFDYVDHTLLNELDRYPRGLPEPMVKRIIYQTLLAVN 405
Query: 818 SVHKMGFIHRDIKPDNILIDRDGHIKLTDFG---LCTGFRWTHDSKYYQSGDHPRQDSMD 874
H+ IHRD+KP+NILI R G +KL DFG + TG P + D
Sbjct: 406 FCHQYNTIHRDVKPENILITRQGQVKLCDFGFARILTG---------------PGDEYTD 540
Query: 875 FSNEWGDPSSCRCGDRLKPLERRAARQHQRCLAHSLVGTPNYIAPEVLL-RTGYTQLCDW 933
+ V T Y APE+L+ T Y D
Sbjct: 541 Y-----------------------------------VATRWYRAPELLVGDTQYGPPVDV 615
Query: 934 WSVGVILFEMLVGQ 947
W++G + E+L GQ
Sbjct: 616 WAIGCVFAELLTGQ 657
>26156
Length = 479
Score = 62.4 bits (150), Expect(2) = 2e-12, Method: Composition-based stats.
Identities = 35/115 (30%), Positives = 63/115 (54%), Gaps = 1/115 (0%)
Frame = -1
Query: 694 RLKRAKMDKSMFVKIKTLGIGAFGEVCLARKVDTKALYATKTLRKKDVLLRNQVAHVKAE 753
R R K+ + F+ ++ +G G++ +V TK +YA K ++K+ V + V+ E
Sbjct: 416 RQFRNKLGLTDFLLLRVIGRGSYAKVLQVEHKRTKRIYAMKVIKKELVNDDEDIDWVQTE 237
Query: 754 RDILAEADN-EWVVRLYYSFQDKDNLYFVMDYIPGGDMMSLLIRMGIFPESLARF 807
+ + A N ++V L+ FQ + L+FV++++ GGD+M + R PE ARF
Sbjct: 236 KHVFETATNYPFLVGLHSCFQSESRLFFVIEFVNGGDLMFHMQRQRRLPEEHARF 72
Score = 29.3 bits (64), Expect(2) = 2e-12, Method: Composition-based stats.
Identities = 11/24 (45%), Positives = 17/24 (70%)
Frame = -3
Query: 807 FYIAELTCAVESVHKMGFIHRDIK 830
FY AE+ A+ +HK G ++RD+K
Sbjct: 75 FYSAEICLALNFLHKRGIVYRDLK 4
>15910
Length = 1361
Score = 65.9 bits (159), Expect = 9e-11, Method: Compositional matrix adjust.
Identities = 59/214 (27%), Positives = 89/214 (41%), Gaps = 1/214 (0%)
Frame = +2
Query: 789 DMMSLLIRMGIFPESLARFYIAELTCAVESVHKMGFIHRDIKPDNILIDRDGHIKLTDFG 848
++ ++ G + E A I+++ V+ +H G +HRD+KP+N+L +
Sbjct: 422 ELFDRIVTRGQYTEKDAARAISDILHGVQYIHANGVVHRDLKPENLLYE----------- 568
Query: 849 LCTGFRWTHDSKYYQSGDHPRQDSMDFSNEWGDPSSCRCGDRLKPLERRAARQHQRCLAH 908
C T DSK + DF L R + Q
Sbjct: 569 -CM----TDDSKLKLA---------DFG-----------------LSRIIEPEVQ---MS 646
Query: 909 SLVGTPNYIAPEVLLRTGYTQLCDWWSVGVILFEMLVGQPPFLAQTPLETQMKVINWQTS 968
++ GTP Y APEVL YT D WSVGVI + +L G PF A+ E K+I +
Sbjct: 647 TVCGTPGYCAPEVLKGDKYTPSVDMWSVGVIAYILLCGYEPFFAENEFEMYRKIIKGEYK 826
Query: 969 LHIPPQAKLSPEASDLIIK-LCRGPEDRLGKNGA 1001
+++S A D++ K L P+ RL A
Sbjct: 827 FDEEYWSEISENAKDVVRKLLVIDPKKRLTATEA 928
>21079
Length = 878
Score = 62.0 bits (149), Expect = 1e-09, Method: Composition-based stats.
Identities = 49/207 (23%), Positives = 81/207 (39%), Gaps = 3/207 (1%)
Frame = +1
Query: 765 VVRLYYSFQDKDNLYFVMDYIPGGDMMSLLIRMG-IFPESLARFYIAELTCAVESVHKMG 823
++ L+ +F+ + VM+++ G++ +IR + E ++ ++ V +H
Sbjct: 10 LLMLWDAFEAPRTMVLVMEFVGAGELFERVIRDDFVLTERDCVHFVRQICSGVGYMHTQS 189
Query: 824 FIHRDIKPDNILI--DRDGHIKLTDFGLCTGFRWTHDSKYYQSGDHPRQDSMDFSNEWGD 881
+H D+KP+N+L D IK+ DFGL +++Y+ GD
Sbjct: 190 ILHLDLKPENVLCVSDNSNQIKIIDFGL---------ARFYKPGDS-------------- 300
Query: 882 PSSCRCGDRLKPLERRAARQHQRCLAHSLVGTPNYIAPEVLLRTGYTQLCDWWSVGVILF 941
L GTP +IAPEV+ D WS+GVI +
Sbjct: 301 -------------------------LQVLFGTPEFIAPEVVNYDEINFTTDMWSIGVICY 405
Query: 942 EMLVGQPPFLAQTPLETQMKVINWQTS 968
+L G P T L W TS
Sbjct: 406 ILLSGLSPSRVTTMLRP------WPTS 468
>13066
Length = 551
Score = 60.5 bits (145), Expect = 3e-09, Method: Composition-based stats.
Identities = 38/186 (20%), Positives = 77/186 (41%), Gaps = 1/186 (0%)
Frame = +3
Query: 753 ERDILAEADNEWVVRLYYSFQDKDNLYFVMDYIPGGDMMSLLIRMGIFPESLARFYIAEL 812
E D+L + D+ ++++++ Q + M + GD+++ + +G E A+ + ++
Sbjct: 126 ELDLLTKLDHPYIIQIHSILQRXPKNFIFMRFAERGDLLTYIQEVGFVKEKQAKIWFYQM 305
Query: 813 TCAVESVHKMGFIHRDIKPDNILIDRDGHIKLTDFGLCTGFRWTHDSKYYQSGDHPRQDS 872
T A+ +H HRD+K +NIL+ ++KL DFG
Sbjct: 306 TTALNYLHSYDVAHRDLKCENILLSSHFNVKLADFGF----------------------- 416
Query: 873 MDFSNEWGDPSSCRCGDRLKPLERRAARQHQRCLAHSLVGTPNYIAPEVLLRTGYT-QLC 931
+C C ++ ++ + G+ Y APE++ Y ++
Sbjct: 417 -----------ACAC----------ITESGEKYMSRTYCGSAAYAAPEIVYGAPYAPKVA 533
Query: 932 DWWSVG 937
D WS+G
Sbjct: 534 DAWSLG 551
>16708
Length = 1397
Score = 60.5 bits (145), Expect = 4e-09, Method: Compositional matrix adjust.
Identities = 76/303 (25%), Positives = 129/303 (42%), Gaps = 13/303 (4%)
Frame = -1
Query: 708 IKTLGIGAFGEVCLARKVDTKALYATKTLRKKDVLLRNQVAHVKAERDI-----LAEADN 762
++ LG G FG+V AR + T A KT +L + + V+A I LA+
Sbjct: 1388 LQVLGKGVFGKVYEARLLSTHEKAALKT----SILCHHSLDEVEALGRIEGGFYLAQMFG 1221
Query: 763 EWVVRLYYSFQDKDNLYFVMDYIPGGDMMS------LLIRMGIFPESLARFYIAELTCAV 816
WV L F + L + P ++ + + IR ++ + CA+
Sbjct: 1220 AWVTCL--PFPKMNILLHFYEMGPLCNVYAHYKNKEMPIRWS--NPAMVCCIAGQXVCAL 1053
Query: 817 ESVHKMGFIHRDIKPDNILIDRDGHIKLTDFGLCTGFR-WTHDSKYYQSGDHPRQDSMDF 875
E +H++G +H D+K DN+L+D G+ KLTD+G+ ++ + ++ + SG + F
Sbjct: 1052 EHIHELGVVHMDVKADNVLVDAHGNCKLTDYGIAQLYKVYPAPTETHSSGC---TNKRTF 882
Query: 876 SNEWGDPSSCRCGDRLKPLERRAARQHQRCLAHSLVGTPNYIAPEVLLRTGYTQLCDWWS 935
P++ + P ER + +GT + ++L W
Sbjct: 881 YTR--PPAT------MTPSERFSEEGDG-------IGTDYFRLGQML----------WTL 777
Query: 936 VGVILFEMLVGQPPFLAQTPLETQMKVINWQTSLHIPPQAKLSPEASDLIIKLCRG-PED 994
G +L + V +PP K+ +W + P+++LS SD I KLC G P
Sbjct: 776 TGAVLLHVWVSRPP-----------KLPDWCRT----PESELS-GMSDFIEKLCHGDPNM 645
Query: 995 RLG 997
RLG
Sbjct: 644 RLG 636
>01392
Length = 1806
Score = 59.3 bits (142), Expect = 8e-09, Method: Compositional matrix adjust.
Identities = 48/165 (29%), Positives = 66/165 (40%), Gaps = 8/165 (4%)
Frame = -1
Query: 798 GIFPESLARFYIAELTCAVESVHKMGFIHRDIKPDNIL---IDRDGHIKLTDFGLCTGFR 854
G E A + + A++ +H G HRD+KP+NIL +D +K+ DF L +G
Sbjct: 1806 GHLCEREASLVVRHIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGI- 1630
Query: 855 WTHDSKYYQSGDHPRQDSMDFSNEWGDPSSCRCGDRLKPLERRAARQHQRCLAHSLVGTP 914
SC GD K E VG+
Sbjct: 1629 -----------------------------SCD-GDGTKTPELLTP-----------VGSA 1573
Query: 915 NYIAPEVLL-----RTGYTQLCDWWSVGVILFEMLVGQPPFLAQT 954
Y+APEV+ Y + CD WS+G+IL+ ML G PPF Q
Sbjct: 1572 EYMAPEVVDAWVGDSFSYDKRCDLWSLGIILYIMLCGYPPFYGQC 1438
>01756
Length = 1858
Score = 58.9 bits (141), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 76/268 (28%), Positives = 117/268 (43%), Gaps = 33/268 (12%)
Frame = -3
Query: 687 QKESNYIRLKRAKMDK-SMFVKIKTLGIGAFGEVCLARKVDTKALYATKTLRKKDVLLRN 745
Q+ S Y LK D+ + + K+ +G G FGEV AR TK + A K VL+ N
Sbjct: 1793 QRYSPYETLKFPFCDEDAKYEKLAKIGQGTFGEVFKARCKKTKQVVAMK-----KVLMDN 1629
Query: 746 QVAH--VKAERDI--LAEADNEWVVRLYYSFQDKDN--------LYFVMDYIPGGDMMSL 793
+ + A R+I L ++E VV L K Y V ++ D+ L
Sbjct: 1628 EKEGFPITALREIKILQLLNHENVVDLIEICSTKATSANRYKSMFYLVFEFCEH-DLAGL 1452
Query: 794 LIRMGI---FPESLARFYIAELTCAVESVHKMGFIHRDIKPDNILIDRDGHIKLTDFGLC 850
L M + PE + + +L + +H+ +HRD+K NILI + G +KL DFGL
Sbjct: 1451 LSNMSVVFNLPE--IKEVMKQLMNGLYYIHRNKILHRDMKAANILITKQGVLKLADFGLA 1278
Query: 851 TGF--------RWTHD--SKYYQ-----SGDHPRQDSMDFSNEWGDPSSCRCGDRL--KP 893
F R+T+ + +Y+ GD ++D +WG + C + P
Sbjct: 1277 RAFSVNLRQPNRYTNRVVTLWYRPPELLLGDRNYSTAID---QWG--AGCIMAEMWTRNP 1113
Query: 894 LERRAARQHQRCLAHSLVGTPNYIAPEV 921
+ + Q+Q L L G+ I PEV
Sbjct: 1112 IMQGTTEQNQLTLITQLCGS---ITPEV 1038
>25019
Length = 730
Score = 58.5 bits (140), Expect = 2e-08, Method: Composition-based stats.
Identities = 34/110 (30%), Positives = 45/110 (40%), Gaps = 4/110 (3%)
Frame = +3
Query: 832 DNILIDRDGHIKLTDFGLC----TGFRWTHDSKYYQSGDHPRQDSMDFSNEWGDPSSCRC 887
+N+L+D+DGH+KLTDFGLC TG R TH
Sbjct: 261 ENVLLDKDGHVKLTDFGLCKEAITGTRVTH------------------------------ 350
Query: 888 GDRLKPLERRAARQHQRCLAHSLVGTPNYIAPEVLLRTGYTQLCDWWSVG 937
+ GT Y+APE+L RTG+ + DWWS+G
Sbjct: 351 ---------------------TFCGTIEYMAPEILTRTGHGKAVDWWSLG 437
>13212
Length = 1067
Score = 58.5 bits (140), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 55/211 (26%), Positives = 81/211 (38%), Gaps = 6/211 (2%)
Frame = -1
Query: 807 FYIAELTCAVESVHKMGFIHRDIKPDNILIDRDGHIKLTDFGLCTGFRWTHDSKYYQSGD 866
+ E+ A++ +H+ IHRDIK N+L+ DG +KL DFG+
Sbjct: 968 YVCHEMCMALDFLHRHHVIHRDIKAGNVLLTIDGEVKLADFGVSA--------------- 834
Query: 867 HPRQDSMDFSNEWGDPSSCRCGDRLKPLERRAARQHQRCLAHSLVGTPNYIAPEVLL--- 923
+ Q +R + +GTP ++APEV+L
Sbjct: 833 -----------------------------KNTQTQQKR---DTFIGTPYWMAPEVVLCET 750
Query: 924 --RTGYTQLCDWWSVGVILFEMLVGQPPFLAQTPLETQMKVINWQTSLHIPPQAKLSPEA 981
T Y D WS+GV L E +PP P+ +K+ P+ K +
Sbjct: 749 LKDTPYDFKADIWSLGVTLIEFAQIEPPNKEMHPMRVLIKIHKSDPPTLEKPK-KWTKLF 573
Query: 982 SDLIIK-LCRGPEDRLGKNGADEIKAHPFFK 1011
D I K L + P R A E+ HPF K
Sbjct: 572 KDFIAKCLVKDPNLR---PTAAELLEHPFMK 489
>14126
Length = 1265
Score = 57.4 bits (137), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 83/363 (22%), Positives = 145/363 (39%), Gaps = 38/363 (10%)
Frame = +3
Query: 687 QKESNYIRLKRAKMDKSMFVKIKTLGIGAFGEVCLARKVDTKALY-ATKTLRKKDVLLRN 745
Q ES +R + + ++ +G GA+G V AR + + + A K +R +
Sbjct: 141 QSESAAKMSRRRDSTEQKYEEVAVIGNGAYGTVYKARDLRNQGEFVAMKRIRLNNT---E 311
Query: 746 QVAHVKAERDI-----LAEADNEWVVRL----YYSFQDKD-NLYFVMDYIPGGDMMSLLI 795
+ + A R+I L + ++ VVRL + + D++ L V +YI D+ + L
Sbjct: 312 EGMPMMAIREISMLKQLEQYEHPNVVRLLDVSHNTITDREIRLNLVFEYIEH-DLATYLA 488
Query: 796 RM---GIFPESLARFYIAELTCAVESVHKMGFIHRDIKPDNILIDRDGHIKLTDFGLCTG 852
+ G+ P+ + + +L V+ +H +HRD+KP N+LI +DG +KL DFGL
Sbjct: 489 KCPSPGLGPDRIKDLML-QLLNGVDFLHSNRIVHRDLKPQNLLISKDGRLKLADFGL--- 656
Query: 853 FRWTHDSKYYQSGDHPRQDSMDFSNEWGDPSSCRCGDRLKPLERRAARQHQRCLA-HSLV 911
AR + +A ++V
Sbjct: 657 ----------------------------------------------ARIYSFHMALTTVV 698
Query: 912 GTPNYIAPEVLLRTGYTQLCDWWSVGVILFEMLVGQPPFLAQTPLETQMKVI-------- 963
T Y +PEVL++ Y D WS G I E+ + F + + K+
Sbjct: 699 VTLWYRSPEVLMQAEYGTSVDIWSCGCIFAELFTRRALFKGSSEFDQLKKIFEVIGLPPA 878
Query: 964 -NW--QTSLH---------IPPQA---KLSPEASDLIIKLCRGPEDRLGKNGADEIKAHP 1008
+W S+H +P Q ++ P+A DL+ K+ R + + E HP
Sbjct: 879 GDWPEGVSVHRNSFRPTPPVPLQTLVPEMDPQAKDLMEKMLVFKSGR--RISSRESLLHP 1052
Query: 1009 FFK 1011
+ +
Sbjct: 1053 YLR 1061
>01060
Length = 1800
Score = 57.4 bits (137), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 70/285 (24%), Positives = 112/285 (39%), Gaps = 15/285 (5%)
Frame = +1
Query: 693 IRLKRAKMD----KSMFVKIKTLGIGAFGEVCLARKVDTKALYATKTLRKKDVLLRNQVA 748
+ +KR MD S + +G G +G V R T A K +R LR
Sbjct: 31 LNIKRLMMDFETALSDLTDFQKIGEGTYGVVYKCRHRATGRKLAMKKIR-----LRGSED 195
Query: 749 HV--KAERDI--LAEADNEWVVRLYYSFQDKDNLYFVMDYIPGGDMMSLLIRMGIFPES- 803
V A R+I L E + +V L + + L+ V +++ M L + + FPE
Sbjct: 196 GVPSSAIREIAMLRELRHTNIVCLEDVIMEDERLFLVFEFLS----MDLKMYIDKFPEGV 363
Query: 804 -----LARFYIAELTCAVESVHKMGFIHRDIKPDNILIDRDGHIKLTDFGLCTGFRWTHD 858
L + Y+ ++ + H+ +HRD+KP N+LI+ G IK+ DFG+ F
Sbjct: 364 VLDRRLVKSYVFQIVTGIXFCHQRRIVHRDLKPQNLLINHTGAIKIADFGMARTFAL--- 534
Query: 859 SKYYQSGDHPRQDSMDFSNEWGDPSSCRCGDRLKPLERRAARQHQRCLAHSLVGTPNYIA 918
P+ R H +V T Y A
Sbjct: 535 ----------------------------------PV---------RAYTHEVV-TLWYRA 582
Query: 919 PEVLL-RTGYTQLCDWWSVGVILFEMLVGQPPFLAQTPLETQMKV 962
PE+L+ + Y+ D WS+G I +ML+ P F + ++ K+
Sbjct: 583 PEILMGASKYSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKI 717
>27546
Length = 426
Score = 57.0 bits (136), Expect = 4e-08, Method: Composition-based stats.
Identities = 28/107 (26%), Positives = 57/107 (53%)
Frame = -1
Query: 753 ERDILAEADNEWVVRLYYSFQDKDNLYFVMDYIPGGDMMSLLIRMGIFPESLARFYIAEL 812
E +IL D+ +++++ Q ++ M Y GDM+S + + G E+ + + ++
Sbjct: 330 ELEILTRLDHPNIIQIHSILQRGPKIFIFMRYAEKGDMLSHIKKTGPIDEAQTKVWFFQM 151
Query: 813 TCAVESVHKMGFIHRDIKPDNILIDRDGHIKLTDFGLCTGFRWTHDS 859
A++ +H HRD+K +NIL+ + ++K+ DFG R+ D+
Sbjct: 150 AKALQYLHSHDIAHRDLKCENILLSKRLNVKIADFGFA---RYCRDA 19
>19094
Length = 898
Score = 54.7 bits (130), Expect = 2e-07, Method: Composition-based stats.
Identities = 35/128 (27%), Positives = 52/128 (40%)
Frame = +1
Query: 819 VHKMGFIHRDIKPDNILIDRDGHIKLTDFGLCTGFRWTHDSKYYQSGDHPRQDSMDFSNE 878
+H IHRDIK NIL++ +GH KL DFG+
Sbjct: 106 LHSRRKIHRDIKAGNILLNNEGHAKLADFGV----------------------------- 198
Query: 879 WGDPSSCRCGDRLKPLERRAARQHQRCLAHSLVGTPNYIAPEVLLRTGYTQLCDWWSVGV 938
G + +R ++++GTP ++APEV+ GY + D WS+G+
Sbjct: 199 --------AGQLTDTMAKR----------NTVIGTPYWMAPEVIQEIGYDCVADIWSLGI 324
Query: 939 ILFEMLVG 946
EM G
Sbjct: 325 TALEMAEG 348
>17932
Length = 597
Score = 53.9 bits (128), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 30/73 (41%), Positives = 46/73 (63%)
Frame = -3
Query: 971 IPPQAKLSPEASDLIIKLCRGPEDRLGKNGADEIKAHPFFKTIDFSSDLRQQSASYIPKI 1030
+PP + +S EA DLI +L + RLG E++ HPFFKT+D+ +++R Y+P I
Sbjct: 478 VPPHSSVSKEARDLISQLLSDGKSRLG---WPELQQHPFFKTVDW-ANIRNAMPPYVPSI 311
Query: 1031 THPTDTSNFDPVD 1043
+ DTS+FD V+
Sbjct: 310 SSLDDTSHFDEVE 272
Score = 35.0 bits (79), Expect = 0.17, Method: Compositional matrix adjust.
Identities = 22/68 (32%), Positives = 33/68 (48%), Gaps = 3/68 (4%)
Frame = -2
Query: 933 WWSVGVILFEMLVGQPPFLAQ--TPLETQMKVINWQTSLHIPPQAKLSPEAS-DLIIKLC 989
WWS+GV +EML G PF + + T ++N++T+ P Q ++ A DL
Sbjct: 596 WWSLGVCAYEMLFGCTPFTDDDGSMVATYNNIMNYKTNSSSPSQQRVQRGAGLDLTTSQ* 417
Query: 990 RGPEDRLG 997
R RL
Sbjct: 416 RQVTTRLA 393
>01966
Length = 1735
Score = 53.1 bits (126), Expect = 6e-07, Method: Compositional matrix adjust.
Identities = 30/107 (28%), Positives = 53/107 (49%), Gaps = 6/107 (5%)
Frame = -1
Query: 753 ERDILAEADNEWVVRLYYSFQDKDNLYFVMDYIPGGDMMSLLIRMGIFPES------LAR 806
E +L E + +V L + + L+ V +++ M L + + FPE L +
Sbjct: 1564 EIAMLRELRHTNIVCLEDVIMEDERLFLVFEFLS----MDLKMYIDKFPEGVVLDRRLVK 1397
Query: 807 FYIAELTCAVESVHKMGFIHRDIKPDNILIDRDGHIKLTDFGLCTGF 853
Y+ ++ + H+ +HRD+KP N+LI+ G IK+ DFG+ F
Sbjct: 1396 SYVFQIVTGINFCHQRRIVHRDLKPQNLLINHTGAIKIADFGMARTF 1256
>21433
Length = 590
Score = 52.8 bits (125), Expect = 9e-07, Method: Composition-based stats.
Identities = 50/183 (27%), Positives = 75/183 (40%)
Frame = +2
Query: 808 YIAELTCAVESVHKMGFIHRDIKPDNILIDRDGHIKLTDFGLCTGFRWTHDSKYYQSGDH 867
YI +L+ A+E H IHRDIKP+N+L+ G +K+ DFG W+ +
Sbjct: 182 YIYQLSSALEYCHYRKVIHRDIKPENLLLGLKGDLKIADFG------WSVHA-------- 319
Query: 868 PRQDSMDFSNEWGDPSSCRCGDRLKPLERRAARQHQRCLAHSLVGTPNYIAPEVLLRTGY 927
PSS R ++ GT +Y+ PE++ +
Sbjct: 320 --------------PSSRRT---------------------TMCGTLDYLPPEMVEGKTH 394
Query: 928 TQLCDWWSVGVILFEMLVGQPPFLAQTPLETQMKVINWQTSLHIPPQAKLSPEASDLIIK 987
+ D WS+GV+ +E LVG PP W + + ++P A DLI K
Sbjct: 395 DENVDLWSLGVLCYEFLVGTPPLRPSPTRPPTPASPRWTSG----SPSIVTPGARDLISK 562
Query: 988 LCR 990
L R
Sbjct: 563 LLR 571
>02638
Length = 1490
Score = 52.4 bits (124), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 31/102 (30%), Positives = 52/102 (50%), Gaps = 1/102 (0%)
Frame = +1
Query: 910 LVGTPNYIAPEVLLRTGYTQLCDWWSVGVILFEMLVGQPPFLAQTPLETQMKVINWQTSL 969
L+GT ++APEVL Y + CD WSVG ++ EM +PP+ + + +S+
Sbjct: 16 LLGTIAFMAPEVLRGESYGRACDVWSVGCVMIEMCTCRPPWNSHDISNHLALIFKIASSV 195
Query: 970 HIPPQAK-LSPEASDLIIKLCRGPEDRLGKNGADEIKAHPFF 1010
PP + +SP DL+++ +D + A ++ HP F
Sbjct: 196 DPPPIPENMSPPVRDLMLRCLE--QDSDFRPSAKDLLMHPLF 315
>29581
Length = 1278
Score = 52.4 bits (124), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 48/175 (27%), Positives = 73/175 (41%), Gaps = 2/175 (1%)
Frame = -2
Query: 776 DNLYFVMDYIPGGDMMSLLIRM-GIFPESLARFYIAELTCAVESVHKMGFIHRDIKPDNI 834
D+L+ VM+Y D+ SLL M F ES + + +L + +H+ IHRD+K N+
Sbjct: 1130 DSLFLVMEYCEQ-DLASLLDNMPAPFSESQVKCIVLQLLKGLRYLHEAFIIHRDLKVSNL 954
Query: 835 LIDRDGHIKLTDFGLCTGFRWTHDSKYYQSGDHPRQDSMDFSNEWGDPSSCRCGDRLKPL 894
L+ G +K+ DFGL + +G P KP+
Sbjct: 953 LMTDKGCVKIADFGL--------------------------ARNYGKPQ--------KPM 876
Query: 895 ERRAARQHQRCLAHSLVGTPNYIAPEVLLRT-GYTQLCDWWSVGVILFEMLVGQP 948
+ V T Y APE+L + ++ D WS G IL E+L +P
Sbjct: 875 TPK-------------VVTLWYRAPELLFGSKTHSTAIDMWSAGCILGELLGHKP 750
>26711
Length = 405
Score = 52.0 bits (123), Expect = 1e-06, Method: Composition-based stats.
Identities = 44/173 (25%), Positives = 68/173 (39%), Gaps = 3/173 (1%)
Frame = -2
Query: 816 VESVHKMGFIHRDIKPDNILI--DRDGHIKLTDFGLCTGFRWTHDSKYYQSGDHPRQDSM 873
++ VH G +H D+KP N+L+ D+ ++L DFGL +P Q++
Sbjct: 377 LQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARKL-------------YPPQETF 237
Query: 874 DFSNEWGDPSSCRCGDRLKPLERRAARQHQRCLAHSLVGTPNYIAPEVLLRTGYTQLCDW 933
L H GTP + +PE L + D
Sbjct: 236 --------------------------------LNH---GTPGFTSPEALDVKPISTASDV 162
Query: 934 WSVGVILFEMLVGQPPFLAQTPLETQMKVINWQTSLHIPPQ-AKLSPEASDLI 985
W VGV+ + +L GQ PF A + E+ K S + P + +S +A D I
Sbjct: 161 WGVGVLAYILLSGQSPFQADSATESLKKTQTCDWSFDVCPSFSNMSQDAKDFI 3
>37602
Length = 804
Score = 52.0 bits (123), Expect = 1e-06, Method: Composition-based stats.
Identities = 27/82 (32%), Positives = 41/82 (50%)
Frame = -1
Query: 766 VRLYYSFQDKDNLYFVMDYIPGGDMMSLLIRMGIFPESLARFYIAELTCAVESVHKMGFI 825
V + S+ ++ L+ M+Y GG M + G E F E + +H+ G +
Sbjct: 330 VGYFDSYLRREKLWIAMEYCGGGSMQDIYHVTGPLTEPQIAFVCRETLKGLHYLHRRGKM 151
Query: 826 HRDIKPDNILIDRDGHIKLTDF 847
HRDIK NIL+ +G +KL DF
Sbjct: 150 HRDIKGANILLTEEGDVKLADF 85
>17722
Length = 680
Score = 51.2 bits (121), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 33/87 (37%), Positives = 51/87 (58%), Gaps = 3/87 (3%)
Frame = -3
Query: 932 DWWSVGVILFEMLVGQPPFLAQTPLETQMKVINWQTSLHIPPQAKLSPEASDLIIK-LCR 990
DWW GV+++EM+ G+ PF + + ++I Q ++ P LS EA L+ L +
Sbjct: 675 DWWGTGVVMYEMMCGRLPFYNRDH-DVLFELILLQ-NVKFP--RNLSEEAKTLLSGLLAK 508
Query: 991 GPEDRLGKNGAD--EIKAHPFFKTIDF 1015
P+ RLG + AD EIK HPFF+ I++
Sbjct: 507 NPKRRLGGSEADVTEIKTHPFFQCINW 427
>03508
Length = 1463
Score = 51.2 bits (121), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 22/51 (43%), Positives = 34/51 (66%), Gaps = 1/51 (1%)
Frame = +1
Query: 800 FPESLARFYIAELTCAVESVHKMGFIHRDIKPDNILIDRDG-HIKLTDFGL 849
F + RFY+ EL A++ H MG +HRD+KP N++ID + ++L D+GL
Sbjct: 862 FTDYDIRFYLYELMKALDFCHSMGIMHRDVKPHNVMIDHENKKLRLIDWGL 1014
>06405
Length = 1965
Score = 50.4 bits (119), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 37/157 (23%), Positives = 71/157 (45%), Gaps = 3/157 (1%)
Frame = +1
Query: 697 RAKMDKSMFVKIKTLGIGAFGEVCLARKVDTKALYATKTLRKKDVLLRNQVAHVKAERDI 756
R +++++ LG G +G+V A + A KTL++ + L + + E I
Sbjct: 241 RWEIERTEIAMKHRLGGGQYGDVYEAMWKRYNKIVAVKTLKEDTMALNDFLE----EAAI 408
Query: 757 LAEADNEWVVRLYYSFQDKDNLYFVMDYIPGGDMMSLL---IRMGIFPESLARFYIAELT 813
+ E + +V+L + Y V +++P G+++ L R P +L + ++
Sbjct: 409 MKEMKHPNLVQLLGVCTREPPFYIVTEFMPHGNLLDYLRSSTREENGPTALM-YMATQIA 585
Query: 814 CAVESVHKMGFIHRDIKPDNILIDRDGHIKLTDFGLC 850
+ + FIHRD+ N L+ +K+ DFGL
Sbjct: 586 SGMAYLETKNFIHRDLAARNCLVADSNMVKVADFGLA 696
>18401
Length = 463
Score = 50.1 bits (118), Expect = 5e-06, Method: Compositional matrix adjust.
Identities = 20/42 (47%), Positives = 28/42 (66%)
Frame = -3
Query: 909 SLVGTPNYIAPEVLLRTGYTQLCDWWSVGVILFEMLVGQPPF 950
++V T +Y APEV+L G++ CD WSVG I+FE+ G F
Sbjct: 455 TIVSTRHYRAPEVILELGWSHPCDVWSVGCIMFELYTGYTLF 330
>12786
Length = 460
Score = 50.1 bits (118), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 41/169 (24%), Positives = 64/169 (37%), Gaps = 22/169 (13%)
Frame = -3
Query: 804 LARFYIAELTCAVESVHKMGFIHRDIKPDNILIDRDGHIKLTDFGLCTGFRWTHDSKYYQ 863
+ +FY E+ AV+++H G IH D+KP N ++ G++KL DFG+
Sbjct: 407 MIKFYWREMLRAVKALHNEGVIHSDLKPANFML-VAGNLKLIDFGIANTL---------- 261
Query: 864 SGDHPRQDSMDFSNEWGDPSSCRCGDRLKPLERRAARQHQRCLAHSLVGTPNYIAPEVLL 923
+QD L S VGTP+Y++PE ++
Sbjct: 260 -----QQDK------------------------------TSVLKDSRVGTPSYMSPEAIM 186
Query: 924 ----------------------RTGYTQLCDWWSVGVILFEMLVGQPPF 950
+ G D WS+G IL+ M+ G+ PF
Sbjct: 185 AACDDSADDSMEEDGHRTKPKYKVGVRS--DVWSLGCILYNMVYGRTPF 45
>11185
Length = 473
Score = 48.9 bits (115), Expect = 1e-05, Method: Composition-based stats.
Identities = 35/135 (25%), Positives = 62/135 (45%)
Frame = +1
Query: 812 LTCAVESVHKMGFIHRDIKPDNILIDRDGHIKLTDFGLCTGFRWTHDSKYYQSGDHPRQD 871
L + +H +G + D++P +L+D G +K DFGL SK G++ +
Sbjct: 28 LVTGLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGL---------SKV--EGENLEEL 174
Query: 872 SMDFSNEWGDPSSCRCGDRLKPLERRAARQHQRCLAHSLVGTPNYIAPEVLLRTGYTQLC 931
F+ E GD + + +A + + + S G+P Y+APEV + +
Sbjct: 175 FFKFA-EAGDQWNIQ-----------SAEEMMKQVPTS--GSPTYMAPEVFQGAEPSIMS 312
Query: 932 DWWSVGVILFEMLVG 946
D W++G + +EM G
Sbjct: 313 DLWALGCVFYEMFSG 357
>04591
Length = 1117
Score = 48.1 bits (113), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 26/76 (34%), Positives = 41/76 (53%), Gaps = 1/76 (1%)
Frame = -2
Query: 775 KDNLYFVMDYIPGGDMMSLLIRMGI-FPESLARFYIAELTCAVESVHKMGFIHRDIKPDN 833
K Y + +Y D+ LL + + F + + +++L + +H +HRDIK N
Sbjct: 981 KSTFYLIFEYC-DYDLAGLLNNLRVKFSLADKKNLMSQLLNGLFYIHTKQILHRDIKAAN 805
Query: 834 ILIDRDGHIKLTDFGL 849
IL+ RDG +KL DFGL
Sbjct: 804 ILLTRDGVLKLADFGL 757
>33586
Length = 551
Score = 47.4 bits (111), Expect = 3e-05, Method: Composition-based stats.
Identities = 18/49 (36%), Positives = 34/49 (69%)
Frame = +2
Query: 764 WVVRLYYSFQDKDNLYFVMDYIPGGDMMSLLIRMGIFPESLARFYIAEL 812
++V L+Y+FQ + LY +++++ GGD+ + L + +F E +FY+AEL
Sbjct: 404 FIVHLHYAFQTEGKLYLILEFLRGGDLFTRLSKEVMFTEEDVKFYLAEL 550
>00715
Length = 1788
Score = 47.4 bits (111), Expect = 4e-05, Method: Compositional matrix adjust.
Identities = 41/177 (23%), Positives = 78/177 (44%), Gaps = 1/177 (0%)
Frame = +1
Query: 775 KDNLYFVMDYIPGGDMMSLLIRMGIFPESLARFYIA-ELTCAVESVHKMGFIHRDIKPDN 833
+D + M+Y+ ++ ++L +S R +A ++ + +H + +H D+KP N
Sbjct: 151 EDGAWLAMEYVGPLNLQTILNDHQQDIDSSMRLSLALQMARGLHYLHSINIVHLDLKPAN 330
Query: 834 ILIDRDGHIKLTDFGLCTGFRWTHDSKYYQSGDHPRQDSMDFSNEWGDPSSCRCGDRLKP 893
L+ RD +++ DFG C T +D G + G+ L+
Sbjct: 331 CLLTRDLKLRIADFGCCHQLTPT---------------GLDMGEREGGMA----GNELEL 453
Query: 894 LERRAARQHQRCLAHSLVGTPNYIAPEVLLRTGYTQLCDWWSVGVILFEMLVGQPPF 950
+ A +++ L GT Y APE+L + D +S+G+ L++M Q P+
Sbjct: 454 TPVQGAWKNE------LAGTLAYRAPELLKGLQPSVRSDVYSLGITLWQMCTRQGPY 606
>20152
Length = 445
Score = 47.0 bits (110), Expect = 4e-05, Method: Composition-based stats.
Identities = 40/115 (34%), Positives = 57/115 (49%), Gaps = 2/115 (1%)
Frame = +1
Query: 919 PEVLLRTGY-TQLCDWWSVGVILFEMLVGQPPFLAQTPLETQMKVINWQTSLHIPPQAKL 977
PE+LL Y D WS+GVIL+ ++VG+ PF ET +++ + IPP +
Sbjct: 1 PEILLGDSYDAPAVDVWSLGVILYMLVVGEAPFQEANDSETLTMIMDCR--YQIPPH--I 168
Query: 978 SPEASDLIIK-LCRGPEDRLGKNGADEIKAHPFFKTIDFSSDLRQQSASYIPKIT 1031
S + DLI K L R P DR I AHP+ D + + +Y+P IT
Sbjct: 169 SHKCQDLIEKMLQREPVDRA---SLPHILAHPWLNDGDLTP-----TTAYLPLIT 309
>28638
Length = 1458
Score = 46.6 bits (109), Expect = 5e-05, Method: Compositional matrix adjust.
Identities = 37/132 (28%), Positives = 51/132 (38%), Gaps = 2/132 (1%)
Frame = -1
Query: 821 KMGFIHRDIKPDNILID--RDGHIKLTDFGLCTGFRWTHDSKYYQSGDHPRQDSMDFSNE 878
+M IH D+KP+NIL+ + IK+ DFG
Sbjct: 777 EMNIIHCDLKPENILLCNPKRSAIKIVDFG------------------------------ 688
Query: 879 WGDPSSCRCGDRLKPLERRAARQHQRCLAHSLVGTPNYIAPEVLLRTGYTQLCDWWSVGV 938
SSC+ G R+ + + + Y +PEVLL Y D WS+G
Sbjct: 687 ----SSCQLGQRI----------------YQYIQSRFYRSPEVLLGVPYDLAIDMWSLGC 568
Query: 939 ILFEMLVGQPPF 950
IL EM G+PP
Sbjct: 567 ILVEMHTGEPPL 532
>21808
Length = 1011
Score = 46.6 bits (109), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 25/99 (25%), Positives = 49/99 (49%), Gaps = 1/99 (1%)
Frame = +1
Query: 752 AERDILAEADNEWVVRLYYSFQDKDNLYFVMDYIPGGDMMSLLIRMGIFPESLARFYI-A 810
AE I+ + + +++LY D ++ + + + G ++ L G + A I A
Sbjct: 79 AEAQIMKKLRHPKLIQLYAVCTQDDPIFIITELMKNGSLLEFLQGKGRVLKLPALIDIGA 258
Query: 811 ELTCAVESVHKMGFIHRDIKPDNILIDRDGHIKLTDFGL 849
++ C + + +IHRD+ NIL+ + +K+ DFGL
Sbjct: 259 QIACGMAYLESQNYIHRDLAARNILVSDNNTVKIADFGL 375
>04138
Length = 800
Score = 45.1 bits (105), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 40/129 (31%), Positives = 60/129 (46%), Gaps = 17/129 (13%)
Frame = +1
Query: 819 VHKMGFIHRDIKPDNILIDRDGHIKLTDFGLCTGF--------RWTHD--SKYYQ----- 863
+H+ +HRD+K NILI + G +KL DFGL F R+T+ + +Y+
Sbjct: 61 IHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRPPELL 240
Query: 864 SGDHPRQDSMDFSNEWGDPSSCRCGDRL--KPLERRAARQHQRCLAHSLVGTPNYIAPEV 921
GD ++D +WG + C + P+ + Q+Q L L G+ I PEV
Sbjct: 241 LGDRNYSTAID---QWG--AGCIMAEMWTRNPIMQGTTEQNQLTLITQLCGS---ITPEV 396
Query: 922 LLRTGYTQL 930
G TQL
Sbjct: 397 W--PGVTQL 417
>29590
Length = 320
Score = 44.3 bits (103), Expect = 3e-04, Method: Composition-based stats.
Identities = 24/75 (32%), Positives = 39/75 (52%), Gaps = 2/75 (2%)
Frame = +3
Query: 910 LVGTPNYIAPEVLLRTGYTQLCDWWSVGVILFEMLVGQPPFLAQTPLETQMKVI--NWQT 967
++GTP+Y+APEVL + D WS+GV+ + ML PF+ T + + NW +
Sbjct: 54 IIGTPDYVAPEVLDYEPLSIQTDMWSLGVLSYVMLTACSPFVGITSKKHSATSLRSNWTS 233
Query: 968 SLHIPPQAKLSPEAS 982
+ + L P+ S
Sbjct: 234 QMISSLTSVLMPKTS 278
>32957
Length = 645
Score = 43.5 bits (101), Expect = 5e-04, Method: Composition-based stats.
Identities = 20/54 (37%), Positives = 28/54 (51%)
Frame = +3
Query: 894 LERRAARQHQRCLAHSLVGTPNYIAPEVLLRTGYTQLCDWWSVGVILFEMLVGQ 947
+E+ R C GT Y+APEV R Y + DWW +G++L E+L Q
Sbjct: 15 VEKSGGRTRTFC------GTREYMAPEVHERKEYGKEVDWWGLGILLHELLAAQ 158
>14116
Length = 1017
Score = 43.1 bits (100), Expect = 7e-04, Method: Composition-based stats.
Identities = 32/137 (23%), Positives = 56/137 (40%)
Frame = -1
Query: 808 YIAELTCAVESVHKMGFIHRDIKPDNILIDRDGHIKLTDFGLCTGFRWTHDSKYYQSGDH 867
Y ++ ++ + + F+HRD+ N ++D D H+K+ DFGL R ++ +YY S
Sbjct: 306 YGVDIARGMDYLAGLKFVHRDLAARNCMLDEDFHVKVADFGLA---RDIYEKEYYSS--- 145
Query: 868 PRQDSMDFSNEWGDPSSCRCGDRLKPLERRAARQHQRCLAHSLVGTPNYIAPEVLLRTGY 927
E + A+ + ++A E L + Y
Sbjct: 144 ---------------------------ENKKAKLPVK-----------WMALESLEKGNY 79
Query: 928 TQLCDWWSVGVILFEML 944
D WS GV+L+E+L
Sbjct: 78 DSKTDVWSYGVVLWELL 28
>19301
Length = 712
Score = 42.7 bits (99), Expect = 8e-04, Method: Compositional matrix adjust.
Identities = 19/69 (27%), Positives = 37/69 (53%)
Frame = +2
Query: 780 FVMDYIPGGDMMSLLIRMGIFPESLARFYIAELTCAVESVHKMGFIHRDIKPDNILIDRD 839
+M+Y P G + +L P +L + ++ + +H IHRD+K N+L+ ++
Sbjct: 500 IIMEYCPYGQLYEVLRDGKEIPPALVLDWSKQIASGMNYLHSHKIIHRDLKSPNVLVAKN 679
Query: 840 GHIKLTDFG 848
+K++DFG
Sbjct: 680 DVVKISDFG 706
>11780
Length = 1713
Score = 42.4 bits (98), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 48/187 (25%), Positives = 84/187 (44%), Gaps = 9/187 (4%)
Frame = +3
Query: 709 KTLGIGAFGEVCLARKVDTKALY-----ATKTLRKKDVLLRNQVAHVKAERDILAEADNE 763
+ +G G FG+V K +Y A K L+ KD R + + ++ E ++ ++
Sbjct: 615 EAIGKGDFGDV-------YKGMYRGQPVAIKQLKDKD---RGEQSFLQ-EASVMTSLRHD 761
Query: 764 WVVRLYYSFQDKDNLYFVMDYIPGGDMMSLLIRMG---IFPESLARFYIAELTCA-VESV 819
+VRL + ++ V +++ G+++ L G I + F A TCA +E +
Sbjct: 762 NLVRLI-GVVLGETIFLVTEFMGKGNLVEYLRSRGRSVITKKDQINF--ATDTCAAMEYL 932
Query: 820 HKMGFIHRDIKPDNILIDRDGHIKLTDFGLCTGFRWTHDSKYYQSGDHPRQDSMDFSNEW 879
+HRD+ N+L+ DG K++DFGL + GD Q S+ F +W
Sbjct: 933 ESKRLVHRDLAARNVLVHDDGKAKVSDFGLA------------KFGDFS-QTSVKFPIKW 1073
Query: 880 GDPSSCR 886
P + R
Sbjct: 1074TAPEALR 1094
>32359
Length = 928
Score = 33.5 bits (75), Expect(2) = 0.001, Method: Composition-based stats.
Identities = 26/88 (29%), Positives = 47/88 (53%), Gaps = 6/88 (6%)
Frame = -1
Query: 705 FVKIKTLGIGAFGEVCLARKVDTKALYATKTLRKKDVLLRNQVAHVKAERDILAEADNEW 764
+ K +G G+FG V A+ VDT L A K + +D +N+ E I+ + +++
Sbjct: 424 YTDAKVIGNGSFGVVYQAKLVDTSELVAIKKVL-QDKRFKNR------ELQIMRKLEHQN 266
Query: 765 VVRL----YYSFQDKDNLY--FVMDYIP 786
+V+L Y S + KD ++ V++Y+P
Sbjct: 265 IVKLKFFFYSSGEKKDEVFLNLVLEYVP 182
Score = 27.7 bits (60), Expect(2) = 0.001, Method: Composition-based stats.
Identities = 10/15 (66%), Positives = 12/15 (80%)
Frame = -3
Query: 823 GFIHRDIKPDNILID 837
G HRDIKP N+L+D
Sbjct: 65 GVCHRDIKPQNLLLD 21
>17516
Length = 453
Score = 42.0 bits (97), Expect = 0.001, Method: Composition-based stats.
Identities = 21/43 (48%), Positives = 30/43 (69%), Gaps = 1/43 (2%)
Frame = -3
Query: 906 LAHSLVGTPNYIAPEVLLRTG-YTQLCDWWSVGVILFEMLVGQ 947
+A +L GTP Y+APEVLL+ G Y D +S+ +IL+E+ GQ
Sbjct: 451 IAGTLAGTPVYMAPEVLLQKGQYDMKADVYSLAIILWELWYGQ 323
>28157
Length = 400
Score = 40.8 bits (94), Expect = 0.003, Method: Composition-based stats.
Identities = 31/99 (31%), Positives = 52/99 (52%), Gaps = 7/99 (7%)
Frame = +3
Query: 757 LAEADNEWVVRLYYSFQDKDNLYFVMDYIPGGDMMSLLIRMGIFPESLARF---YIAELT 813
L+ + +V LY + +D + VM+Y GG + ++L G P+ A ++ +
Sbjct: 72 LSRVSHPNIVCLYGACRDHP-VCLVMEYAEGGSLYNVLHGSGPQPQYTAAHAMNWLLQCA 248
Query: 814 CAVESVHKM---GFIHRDIKPDNILIDRDG-HIKLTDFG 848
VE +H M IHRD+KP N+L+ + G +K+ DFG
Sbjct: 249 LGVEYLHGMKPKALIHRDLKPPNLLLIQCGTKLKICDFG 365
>14477
Length = 493
Score = 40.8 bits (94), Expect = 0.003, Method: Composition-based stats.
Identities = 37/156 (23%), Positives = 72/156 (46%), Gaps = 2/156 (1%)
Frame = -1
Query: 711 LGIGAFGEVC--LARKVDTKALYATKTLRKKDVLLRNQVAHVKAERDILAEADNEWVVRL 768
LG G FG V + R D + A K L+ D+ Q +K E +++ + D+ +VRL
Sbjct: 466 LGAGNFGSVMKGVCRLDDREIPVAIKVLKNADLDPSVQSELIK-EAEVMKKMDHMHIVRL 290
Query: 769 YYSFQDKDNLYFVMDYIPGGDMMSLLIRMGIFPESLARFYIAELTCAVESVHKMGFIHRD 828
+ + + V++ G + L + P + +++ +E + F+HRD
Sbjct: 289 I-GLCEGETMMLVLELAKLGPLNKFLPKNKHLPLWNILELMWQVSQGMEYLEANKFVHRD 113
Query: 829 IKPDNILIDRDGHIKLTDFGLCTGFRWTHDSKYYQS 864
+ NIL+ + K++DFG+ + ++ YY +
Sbjct: 112 LAARNILLCDEHFAKISDFGMSKTL--SRENNYYMA 11
>19761
Length = 473
Score = 40.0 bits (92), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 32/146 (21%), Positives = 51/146 (34%), Gaps = 2/146 (1%)
Frame = -3
Query: 800 FPESLARFYIAELTCAVESVHKMG--FIHRDIKPDNILIDRDGHIKLTDFGLCTGFRWTH 857
PE L ++ + A+ +H +HRD+KP NI + G ++L D GL
Sbjct: 432 LPERLIVCWLMQTASALNYMHTHTPVILHRDLKPQNIYVTEKGDVRLGDLGLARKLTGPA 253
Query: 858 DSKYYQSGDHPRQDSMDFSNEWGDPSSCRCGDRLKPLERRAARQHQRCLAHSLVGTPNYI 917
D A S VGT Y+
Sbjct: 252 D-----------------------------------------------FATSQVGTIMYL 214
Query: 918 APEVLLRTGYTQLCDWWSVGVILFEM 943
+PE+L + Y D WS+G + +++
Sbjct: 213 SPEILSQQPYNSKSDIWSLGCVFYDI 136
>04852
Length = 1462
Score = 39.7 bits (91), Expect = 0.007, Method: Compositional matrix adjust.
Identities = 35/144 (24%), Positives = 59/144 (40%), Gaps = 1/144 (0%)
Frame = +1
Query: 808 YIAELTCAVESVHKMGFIHRDIKPDNILIDRDGHIKLTDFGLCTGFRWTHDSKYYQSGDH 867
Y ++ +E + IHRD+ N+L+ + +K+ DFGL ++GD+
Sbjct: 340 YAFQIARGMEFLASRKCIHRDLAARNVLVTEEHVLKIADFGLS------------RTGDY 483
Query: 868 PRQDSMDFSNEWGDPSSCRCGDRLKPLERRAARQHQRCLAHSLVGTPNYIAPEVLLRTGY 927
++ R G RL P++ ++APE L Y
Sbjct: 484 YKK---------------RSGGRL-PVK--------------------WMAPEALFDMRY 555
Query: 928 TQLCDWWSVGVILFEML-VGQPPF 950
T D WS GV+L+E+ +G P+
Sbjct: 556 TTKSDVWSFGVVLWEIFSLGGMPY 627
>18481
Length = 437
Score = 39.7 bits (91), Expect = 0.007, Method: Composition-based stats.
Identities = 19/54 (35%), Positives = 31/54 (57%), Gaps = 3/54 (5%)
Frame = -1
Query: 811 ELTCAVESVHKMGFIHRDIKPDNILIDRDGH---IKLTDFGLCTGFRWTHDSKY 861
+L +E +H+ FIHRD+KPDN L+ H + + DFGL ++ T + +
Sbjct: 173 QLLSRLEFIHQKCFIHRDLKPDNFLMGLGRHCHRLYIIDFGLSKRYKDTQGTMH 12
>20640
Length = 1492
Score = 38.9 bits (89), Expect = 0.013, Method: Composition-based stats.
Identities = 17/45 (37%), Positives = 26/45 (57%)
Frame = +1
Query: 823 GFIHRDIKPDNILIDRDGHIKLTDFGLCTGFRWTHDSKYYQSGDH 867
G++HRD+ N L+ D +K++DFGL R H YY+ +H
Sbjct: 4 GYVHRDLATRNCLVGHDLVVKISDFGLA---RSVHSVDYYRGSEH 129
>01718
Length = 959
Score = 38.5 bits (88), Expect = 0.014, Method: Compositional matrix adjust.
Identities = 43/159 (27%), Positives = 66/159 (41%), Gaps = 18/159 (11%)
Frame = +3
Query: 711 LGIGAFGEV----------CLARKVDTKALYATKTLRKKDVLLRNQVAHVKAERDILAEA 760
+G G F EV +A K++T LR+ +L R Q A++
Sbjct: 171 IGAGFFSEVFKVTHRITGQVMALKMNTMTSNRHNMLREVQLLNRLQHANI---------- 320
Query: 761 DNEWVVRLYYSFQDKDNLYFVMDYIPGGDMMSLLIRMGIFPESLARFYIAELTCAV---- 816
+R + L+ + +YIP G++ LL + E L +LT +
Sbjct: 321 -----LRFMGVCVHEGQLHALTEYIPSGNLEQLLEKKD---EELPWTQRIQLTLGLARGL 476
Query: 817 ESVHKMGFIHRDIKPDNILIDRDG----HIKLTDFGLCT 851
+ +H FIHRD+ NILI R+ H + DFGL T
Sbjct: 477 DYLHSTRFIHRDLTSKNILIRREDNHGYHAVIADFGLAT 593
>09007
Length = 1440
Score = 38.1 bits (87), Expect = 0.020, Method: Compositional matrix adjust.
Identities = 53/210 (25%), Positives = 86/210 (40%), Gaps = 13/210 (6%)
Frame = -1
Query: 690 SNYIRLKRAK--MDKSMFVKIKTLGIGAFGEVCLA---RKVDTKALYATKTLRKKDVLLR 744
S +R R K + K K+LG G FG V A + K A K L KD + +
Sbjct: 924 SAVVRPARGKQLISKDCVALSKSLGQGHFGTVRQAIWTAESGEKVQVAVKCL-SKDKIHK 748
Query: 745 NQVAHVKAERDILAEADNEWVVRLYYSFQDKD-NLYFVMDYIPGGDMMSLL----IRMGI 799
+ +K E I+ D+E +VR+Y D ++ V + P ++ + R+
Sbjct: 747 DGQEFLK-ETAIMQMLDHENIVRVYGVVMDNGADIMLVTELAPMRSLLECVKEVSARVDF 571
Query: 800 FPESLARFYIAELTC-AVESVHKMGFIHRDIKPDNILIDRDGHIKLTDFGLCTGFRWTHD 858
L F ++ C + + +HRD+ NIL+ +K++D G+
Sbjct: 570 SVPRLCDF--SQQVCDGMSYLESKRLVHRDLAARNILLFSKSKVKISDVGVSGAL--GAG 403
Query: 859 SKYYQSGDHPRQDSMDFSN--EWGDPSSCR 886
+YYQS Q ++ N W P S R
Sbjct: 402 KEYYQS-----QQTIHLQNAVAWCAPESFR 328
>07833
Length = 1504
Score = 38.1 bits (87), Expect = 0.020, Method: Compositional matrix adjust.
Identities = 26/86 (30%), Positives = 41/86 (47%), Gaps = 3/86 (3%)
Frame = -3
Query: 911 VGTPNYIAPEVLLR---TGYTQLCDWWSVGVILFEMLVGQPPFLAQTPLETQMKVINWQT 967
V +P ++APE L R T+ D WS ++++E+ + PF + +E MKV
Sbjct: 1139 VYSPAWMAPEALQRRPDDINTRAADMWSFAILMWELETREVPFAELSSMEVGMKVALEGL 960
Query: 968 SLHIPPQAKLSPEASDLIIKLCRGPE 993
+ IPP L +IK+C E
Sbjct: 959 RISIPPGISLH---MSRLIKICMNEE 891
>00638
Length = 1595
Score = 38.1 bits (87), Expect = 0.022, Method: Composition-based stats.
Identities = 15/32 (46%), Positives = 22/32 (68%)
Frame = +2
Query: 806 RFYIAELTCAVESVHKMGFIHRDIKPDNILID 837
RFY+ EL A++ H MG +HRD+KP L++
Sbjct: 425 RFYLYELMKALDFCHSMGIMHRDVKPSPPLVN 520
>07836
Length = 1478
Score = 37.7 bits (86), Expect = 0.025, Method: Compositional matrix adjust.
Identities = 31/104 (29%), Positives = 46/104 (44%), Gaps = 9/104 (8%)
Frame = -1
Query: 778 LYFVMDYIPGGDMMS-LLIRMGIFPESLARFYIAELTCAVESVH--------KMGFIHRD 828
L+ + DY G + LL R+ E LA + A C + +H K HRD
Sbjct: 1328 LFLITDYHENGSLHDYLLSRVLDSSEMLALAHSA--ICGLAHLHIEIFGTRGKPAIAHRD 1155
Query: 829 IKPDNILIDRDGHIKLTDFGLCTGFRWTHDSKYYQSGDHPRQDS 872
IK NIL+ ++G + D GL R+ +S +PRQ +
Sbjct: 1154 IKSKNILVKKNGTCCIADLGL--AVRYISESNEVDVAPNPRQGT 1029
>07291
Length = 833
Score = 36.6 bits (83), Expect = 0.052, Method: Compositional matrix adjust.
Identities = 25/133 (18%), Positives = 51/133 (38%), Gaps = 1/133 (0%)
Frame = +1
Query: 819 VHKMGFIHRDIKPDNILIDRDGHIKLTDFGLCTGFRWTHDSKYYQSGDHPRQDSMDFSNE 878
+ ++ +HR++ N ++ DG ++L+D+G+ YY + D P +D +
Sbjct: 97 LQEVKVVHRNLAARNCIVTEDGRLQLSDYGVTGSL---FPQSYYTADDSPARDLV----- 252
Query: 879 WGDPSSCRCGDRLKPLERRAARQHQRCLAHSLVGTPNYIAPEVLLRTGYTQLCDWWSVGV 938
++APE + ++ D W+ GV
Sbjct: 253 ------------------------------------KWMAPETIDNFHFSSKSDVWAFGV 324
Query: 939 ILFEMLV-GQPPF 950
+L+E+L G P+
Sbjct: 325 VLWELLTRGITPY 363
>07940
Length = 1336
Score = 36.6 bits (83), Expect = 0.065, Method: Compositional matrix adjust.
Identities = 40/178 (22%), Positives = 72/178 (40%), Gaps = 9/178 (5%)
Frame = -3
Query: 782 MDYIPGGDMMSL--------LIRMGIFPESLARFYIAELTCAVESVHKMGFIHRDIKPDN 833
+ +IPG +S +++M + P+ L Y ++ +E + IHRD+ N
Sbjct: 428 LGFIPGTSTVSFSTGSHRQDMLKM-LTPKDLIS-YAYQVARGMEYLASKQCIHRDLAARN 255
Query: 834 ILIDRDGHIKLTDFGLCTGFRWTHDSKYYQSGDHPRQDSMDFSNEWGDPSSCRCGDRLKP 893
+L+ + +K+ DFGL ++ Q D+ R+ + D P
Sbjct: 254 VLVAEEYVLKIADFGL---------TRNLQQFDYYRKTT----------------DGRLP 150
Query: 894 LERRAARQHQRCLAHSLVGTPNYIAPEVLLRTGYTQLCDWWSVGVILFEML-VGQPPF 950
++ ++APE L YT D WS GV+L+E+ +G P+
Sbjct: 149 VK--------------------WMAPEALFDRKYTSKSDVWSYGVLLWEIFTLGGNPY 36
>26009
Length = 886
Score = 35.0 bits (79), Expect = 0.18, Method: Compositional matrix adjust.
Identities = 13/32 (40%), Positives = 22/32 (68%)
Frame = +3
Query: 805 ARFYIAELTCAVESVHKMGFIHRDIKPDNILI 836
A+ + +L A++ +H +HRDIKP+N+LI
Sbjct: 717 AKSVMKQLVSALDFMHSKQLVHRDIKPENVLI 812
>00392
Length = 668
Score = 34.7 bits (78), Expect = 0.20, Method: Compositional matrix adjust.
Identities = 42/208 (20%), Positives = 80/208 (38%), Gaps = 8/208 (3%)
Frame = +3
Query: 751 KAERDILAEADNEWVVRLY-----YSFQDKDNLYFVMDYIPGGDMMSLLIRMGIFPESLA 805
K E ++L E + +VR + ++ +++ + V + + G + + L R +
Sbjct: 75 KEEAEMLKELQHPNIVRFFDYWEEHNHRNRKVIILVTELMTSGTLKTYLKRFKKPNVKIL 254
Query: 806 RFYIAELTCAVESVHKMG--FIHRDIKPDNILIDR-DGHIKLTDFGLCTGFRWTHDSKYY 862
+ + ++ + +H IHRD+K DNI I G +K+ D GL T
Sbjct: 255 KNWCRQVLKGLYFLHTRTPPVIHRDLKCDNIFITGPTGSVKIGDLGLAT----------- 401
Query: 863 QSGDHPRQDSMDFSNEWGDPSSCRCGDRLKPLERRAARQHQRCLAHSLVGTPNYIAPEVL 922
LK + A S++GTP ++APE +
Sbjct: 402 ----------------------------LK----------NQSFAKSVIGTPEFMAPE-M 464
Query: 923 LRTGYTQLCDWWSVGVILFEMLVGQPPF 950
Y + D ++ G+ + EM + P+
Sbjct: 465 YEEHYDEAVDVYAFGMCMLEMASSEYPY 548
>31489
Length = 329
Score = 34.7 bits (78), Expect = 0.23, Method: Composition-based stats.
Identities = 19/82 (23%), Positives = 41/82 (50%)
Frame = +3
Query: 754 RDILAEADNEWVVRLYYSFQDKDNLYFVMDYIPGGDMMSLLIRMGIFPESLARFYIAELT 813
R+IL D+ Y+ F+D ++ +M+ D+ ++ E R+++ ++
Sbjct: 48 REILKPKDS------YHDFKDIHVVFDLME----SDLHRIIYSDQPLTEEHIRYFLYQIL 197
Query: 814 CAVESVHKMGFIHRDIKPDNIL 835
++ +H +HRD+KP N+L
Sbjct: 198 RGLKYIHSANVVHRDLKPSNLL 263
>12672
Length = 773
Score = 34.3 bits (77), Expect = 0.33, Method: Composition-based stats.
Identities = 31/132 (23%), Positives = 49/132 (37%)
Frame = +3
Query: 815 AVESVHKMGFIHRDIKPDNILIDRDGHIKLTDFGLCTGFRWTHDSKYYQSGDHPRQDSMD 874
++ ++ G +HRDIK NIL+D + K+ DF P +
Sbjct: 27 GIQYLNDNGHVHRDIKTANILLDSEYTAKVGDFATVV--------------SAPSGEGKT 164
Query: 875 FSNEWGDPSSCRCGDRLKPLERRAARQHQRCLAHSLVGTPNYIAPEVLLRTGYTQLCDWW 934
N A ++GT Y+APE + T+L D +
Sbjct: 165 VQN-----------------------------ASVVIGTAAYLAPEAIHFDVSTKL-DSY 254
Query: 935 SVGVILFEMLVG 946
S GV+L E++ G
Sbjct: 255 SFGVVLLEVITG 290
>13078
Length = 773
Score = 33.9 bits (76), Expect = 0.42, Method: Compositional matrix adjust.
Identities = 12/25 (48%), Positives = 17/25 (68%)
Frame = -1
Query: 926 GYTQLCDWWSVGVILFEMLVGQPPF 950
G++Q CD WS+G I+FE+ G F
Sbjct: 749 GWSQPCDVWSIGCIMFELYTGYTLF 675
>29360
Length = 363
Score = 33.5 bits (75), Expect = 0.47, Method: Composition-based stats.
Identities = 30/120 (25%), Positives = 53/120 (44%), Gaps = 3/120 (2%)
Frame = +3
Query: 720 CLARKVDTKALYATKTLRKKDVLLRNQVAHVKAERDILAE-ADNEWVVRLYYSFQDKDNL 778
C K T + A K L+ R V + + E AD+ VR + FQ K++
Sbjct: 3 CKCWKKGTSEIVAIKILKNHPSYARQGQIEVSILQRLSQESADDYNFVRAFECFQHKNHT 182
Query: 779 YFVMDYIPGGDMMSLLIRMGIFPESLA--RFYIAELTCAVESVHKMGFIHRDIKPDNILI 836
V + + ++ L + P L R ++ A+ + ++G IH D+KP+NI++
Sbjct: 183 CLVFEMLEQ-NLYDFLKQNKFQPLPLKYIRPITQQVLTALRKLKQLGLIHADLKPENIML 359
>18996
Length = 491
Score = 33.5 bits (75), Expect = 0.47, Method: Compositional matrix adjust.
Identities = 35/141 (24%), Positives = 53/141 (37%), Gaps = 1/141 (0%)
Frame = +2
Query: 825 IHRDIKPDNILIDRDGHIKLTDFGLCTGFRWTHDSKYYQSGDHPRQDSMDFSNEWGDPSS 884
IHRD+ NIL+DR +K++DFGL ++ + YY
Sbjct: 2 IHRDLAARNILVDRSC-VKISDFGLA---QFANADGYYYG-------------------- 109
Query: 885 CRCGDRLKPLERRAARQHQRCLAHSLVGTPNYIAPEVLLRTGYTQLCDWWSVGVILFEML 944
R P++ + +PE + ++ D WS GV LFEM
Sbjct: 110 --ISQRDIPIK--------------------WYSPEAIETCKFSSYSDVWSYGVTLFEMF 223
Query: 945 V-GQPPFLAQTPLETQMKVIN 964
G+ P L TQ + +N
Sbjct: 224 SRGEIPNLLPGHDLTQEEFLN 286
>11404
Length = 563
Score = 33.5 bits (75), Expect = 0.57, Method: Composition-based stats.
Identities = 37/132 (28%), Positives = 60/132 (45%), Gaps = 6/132 (4%)
Frame = +1
Query: 711 LGIGAFGEVCLARKVDTKALYATKTLRKKDVLLRNQVAHVKA-ERDILAEADNEW-VVRL 768
+G G+FG+V A A K ++ K L VK E + DN++ +VRL
Sbjct: 163 IGKGSFGQVVKAYDHTDNEQVAIKIIKNKKPFLNQAQIEVKLLEMMNRHDTDNKYYIVRL 342
Query: 769 YYSFQDKDNLYFVMDYIPGGDMMSLLIRMGIFPESL--ARFYIAELTCAVE--SVHKMGF 824
F + +L V + + ++ LL SL R + +L A+ + +M
Sbjct: 343 KRHFMFRSHLCLVFELL-SYNLYDLLRNTNFRGVSLNLTRKFAQQLCTALLFLATPEMSI 519
Query: 825 IHRDIKPDNILI 836
IH D+KP+NIL+
Sbjct: 520 IHCDLKPENILL 555
>37063
Length = 455
Score = 32.3 bits (72), Expect = 1.0, Method: Composition-based stats.
Identities = 15/35 (42%), Positives = 21/35 (60%), Gaps = 5/35 (14%)
Frame = -2
Query: 911 VGTPNYIAPEVL-----LRTGYTQLCDWWSVGVIL 940
VG+ Y+APEV+ Y + CD WS+G+IL
Sbjct: 325 VGSAEYMAPEVVDAWVGESFSYDKRCDMWSLGIIL 221
>17300
Length = 480
Score = 32.3 bits (72), Expect = 1.2, Method: Composition-based stats.
Identities = 29/130 (22%), Positives = 51/130 (39%), Gaps = 1/130 (0%)
Frame = +1
Query: 822 MGFIHRDIKPDNILIDRDGHIKLTDFGLCTGFRWTHDSKYYQSGDHPRQDSMDFSNEWGD 881
MG++HRD+ NIL++ K+ DFGL S + ++ +
Sbjct: 31 MGYVHRDLAARNILVNEILVCKVADFGL----------------------SREIESDTTE 144
Query: 882 PSSCRCGDRLKPLERRAARQHQRCLAHSLVGTPNYIAPEVLLRTGYTQLCDWWSVGVILF 941
+ G ++ P+ + APE + +T D WS GV+++
Sbjct: 145 GAYTTKGGKI-PVR--------------------WTAPEAIAYRKFTSASDVWSFGVVMW 261
Query: 942 E-MLVGQPPF 950
E M G+ P+
Sbjct: 262 EVMSYGERPY 291
>03275
Length = 3821
Score = 32.0 bits (71), Expect = 1.4, Method: Compositional matrix adjust.
Identities = 38/133 (28%), Positives = 55/133 (41%), Gaps = 34/133 (25%)
Frame = +3
Query: 841 HIKLTDFGLCTG----FRWT----HDSKYY----QSGDHPRQDSMDFSNEWG--DPSSCR 886
H ++FGL TG RW HD ++ S H QDS+ EW P +
Sbjct: 3105 HYLRSNFGLVTGAASRHRWKPGYGHDCAHHGCLPHSAHHRHQDSL---GEWKLPVPGYGQ 3275
Query: 887 CGDRLKPLERRAARQH-QRCLAHSLVGTPNYI--APEVLLRTG----------------- 926
C D L++R ++ QR +AH + + + P VLL+T
Sbjct: 3276 CSD--THLQKRGNKRFVQRTIAH-VXARRSLLRPIPHVLLQTQDVQPTQYVWMWV*TTSR 3446
Query: 927 YTQLCDWWSVGVI 939
+ Q CDWW GV+
Sbjct: 3447 FLQCCDWWCPGVV 3485
>01106
Length = 878
Score = 31.2 bits (69), Expect = 2.3, Method: Composition-based stats.
Identities = 46/179 (25%), Positives = 76/179 (42%), Gaps = 13/179 (7%)
Frame = +3
Query: 671 VGLSQDAQDQMRKMLCQKESNYIRLKRAKMDKSMFVKIKTLGIGAFGEVCLARKVDTKAL 730
+G D Q+ R C+ Y +K + + I+ LG G F V L + K
Sbjct: 231 LGSDDDEQEDPRDY-CK--GGYHPVKNGDLFNGRYHVIRKLGWGHFSTVWLCWDLTCKRF 401
Query: 731 YATKTLRKKDVLLRNQVAHVK-----AERDILAEADNEWVVRLYYSFQ----DKDNLYFV 781
A K ++ + VK E D+ A+ V+L F+ + ++ V
Sbjct: 402 VALKVVKSAQHYTETALDEVKLLKCVRESDV-ADPARAKCVQLLDDFKISGVNGTHVAMV 578
Query: 782 MDYIPGGDMMSLLIR---MGIFPESLARFYIAELTCAVESVH-KMGFIHRDIKPDNILI 836
+ + G +++ L+IR GI P + I ++ + +H K IH DIKP+NILI
Sbjct: 579 FEVL-GYNLLKLIIRSNYQGI-PIHNVKLIIRQVLEGLSYMHAKCRIIHTDIKPENILI 749
>31120
Length = 439
Score = 30.8 bits (68), Expect = 2.9, Method: Composition-based stats.
Identities = 13/22 (59%), Positives = 17/22 (77%)
Frame = +1
Query: 929 QLCDWWSVGVILFEMLVGQPPF 950
++ D WS+GVILF ML G+ PF
Sbjct: 31 KMADAWSLGVILFIMLNGKMPF 96
>17637
Length = 447
Score = 30.8 bits (68), Expect = 3.3, Method: Composition-based stats.
Identities = 16/56 (28%), Positives = 29/56 (51%), Gaps = 1/56 (1%)
Frame = +1
Query: 905 CLAHSLVGTPNYIAPEVLLRTGYTQLCDWWSVGVILFEM-LVGQPPFLAQTPLETQ 959
CL +++ E L ++ Y + D WS GV+++EM +G+ P+ P E +
Sbjct: 82 CLGDGEYRPIKWLSLEALQKSHYNEGSDVWSFGVLMWEMCTLGKLPYAEIDPYEME 249
>36481
Length = 806
Score = 30.0 bits (66), Expect = 5.9, Method: Composition-based stats.
Identities = 14/38 (36%), Positives = 20/38 (52%)
Frame = +2
Query: 798 GIFPESLARFYIAELTCAVESVHKMGFIHRDIKPDNIL 835
G +P R +L AV +H+ H D+KP+NIL
Sbjct: 656 GAYPIEQVRHISYQLCYAVNFLHENQLTHTDLKPENIL 769
>21800
Length = 855
Score = 29.6 bits (65), Expect = 6.9, Method: Composition-based stats.
Identities = 20/54 (37%), Positives = 30/54 (55%), Gaps = 4/54 (7%)
Frame = +2
Query: 787 GGDMMSLLIR---MGIFPESLARFYIAELTCAVESVH-KMGFIHRDIKPDNILI 836
G +++ L+IR GI P + I ++ + +H K IH DIKP+NILI
Sbjct: 578 GYNLLKLIIRSNYQGI-PVHNVKLIIRQVLEGLNYLHAKCNIIHTDIKPENILI 736
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000280326 | hsapiens_gene_ensembl | T-complex
protein 1 subunit epsilon (TCP-1-epsilon) (CCT-epsilon).
[Source:Uniprot/SWISSPROT;Acc:P48643]
(541 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
01159 843 0.0
12796 202 3e-52
05356 107 4e-48
06409 181 9e-46
02673 161 6e-40
29631 92 7e-29
09900 119 3e-27
29864 107 1e-23
33770 97 2e-20
30661 86 4e-17
10291 71 1e-12
17249 47 2e-05
29327 32 0.55
09856 30 2.1
>01159
Length = 2613
Score = 843 bits (2178), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 405/539 (75%), Positives = 472/539 (87%), Gaps = 1/539 (0%)
Frame = +3
Query: 1 MAS-MGTLAFDEYGRPFLIIKDQDRKSRLMGLEALKSHIMAAKAVANTMRTSLGPNGLDK 59
MAS MG +AFDEYGRPF+I++DQD+KSRL G+EA KSHI+AAK+VA+ ++TSLGP GLDK
Sbjct: 90 MASPMGQIAFDEYGRPFIILRDQDKKSRLTGIEAHKSHILAAKSVASILKTSLGPKGLDK 269
Query: 60 MMVDKDGDVTVTNDGATILSMMDVDHQIAKLMVELSKSQDDEIGDXXXXXXXXXXXXXXX 119
MMV DGDVTVTNDGATIL MMDVDHQIAKLMV+LSKSQDDEIGD
Sbjct: 270 MMVSGDGDVTVTNDGATILDMMDVDHQIAKLMVQLSKSQDDEIGDGTTGVVVLAGALLEQ 449
Query: 120 XXQLLDRGIHPIRIADGYEQAARVAIEHLDKISDSVLVDIKDTEPLIQTAKTTLGSKVVN 179
+LLDRGIHPIRIADGYE AA+ A+E LDKISD+ VD+K+ EPLI+ A TTLGSK+VN
Sbjct: 450 AEKLLDRGIHPIRIADGYEIAAKCAVETLDKISDNYEVDLKNAEPLIKLAMTTLGSKIVN 629
Query: 180 SCHRQMAEIAVNAVLTVADMERRDVDFELIKVEGKVGGRLEDTKLIKGVIVDKDFSHPQM 239
CHRQMA+IAV+A+++VAD++R+DVDFELIKVEGKVGG+LEDT L+KGV+VDKD SHPQM
Sbjct: 630 RCHRQMAKIAVDAIMSVADLKRKDVDFELIKVEGKVGGKLEDTMLVKGVVVDKDMSHPQM 809
Query: 240 PKKVEDAKIAILTCPFEPPKPKTKHKLDVTSVEDYKALQKYEKEKFEEMIQQIKETGANL 299
PK V+DAKIAILTCPFEPPKPKTKHKLD+TSVEDYK L++YE KFE M+Q +K+ GANL
Sbjct: 810 PKVVKDAKIAILTCPFEPPKPKTKHKLDITSVEDYKKLREYELNKFESMVQSVKDKGANL 989
Query: 300 AICQWGFDDEANHLLLQNNLPAVRWVGGPEIELIAIATGGRIVPRFSELTAEKLGFAGLV 359
ICQWGFDDEANHLLLQ LPAVRWVGGPEIELIAIATGGRIVPRF ELT EKLG AG+V
Sbjct: 990 VICQWGFDDEANHLLLQRELPAVRWVGGPEIELIAIATGGRIVPRFEELTTEKLGKAGIV 1169
Query: 360 QEISFGTTKDKMLVIEQCKNSRAVTIFIRGGNKMIIEEAKRSLHDALCVIRNLIRDNRVV 419
+E++FGTTKD+MLVIE+C N+RAVTIFIRGGNKMI+EEAKRSLHDALCVIRNL+RDNRVV
Sbjct: 1170RELTFGTTKDRMLVIEECLNTRAVTIFIRGGNKMIVEEAKRSLHDALCVIRNLVRDNRVV 1349
Query: 420 YGGGAAEISCALAVSQEADKCPTLEQYAMRAFADALEVIPMALSENSGMNPIQTMTEVRA 479
YGGGA EI+ ++AV++ ADK TLEQYA+R+F++ALE +P+AL+ENSG+ PIQT+ EV++
Sbjct: 1350YGGGAPEIAASVAVAEAADKISTLEQYAVRSFSEALEAVPLALAENSGLAPIQTLAEVKS 1529
Query: 480 RQVKEMNPALGIDCLHKGTNDMKQQHVIETLIGKKQQISLATQMVRMILKIDDIRKPGE 538
RQVKE NP LGIDCL KGTNDMK+Q+VIETL KKQQI LATQ+VRMILKIDDIR P +
Sbjct: 1530RQVKEKNPRLGIDCLLKGTNDMKEQNVIETLTAKKQQILLATQLVRMILKIDDIRAPSD 1706
>12796
Length = 1316
Score = 202 bits (514), Expect = 3e-52, Method: Compositional matrix adjust.
Identities = 128/339 (37%), Positives = 190/339 (56%), Gaps = 9/339 (2%)
Frame = -3
Query: 204 VDFELIKVEGKVGGRLEDTKLIKGVIVDKDFSHPQMPKKVEDAKIAILTCPFEPPKPKTK 263
VD + IKV +GG +EDT+L+ G++ + PK++E AKI ++ PK
Sbjct: 1308 VDLKNIKVIRSLGGTVEDTELVNGLVFTSRSAGTNAPKRIEKAKIGLIQFCISAPKTDMD 1129
Query: 264 HKLDVTSVEDYKALQKYEKEK---FEEMIQQIKETGANLAICQWGF-----DDEANHLLL 315
H + V+ DY A+ + KE+ +++QIK+ G N+ + Q D A H L
Sbjct: 1128 HNVIVS---DYAAMDRVLKEERSYILNIVKQIKKAGCNVLLVQKSILRDAVSDLAQHFLD 958
Query: 316 QNNLPAVRWVGGPEIELIAIATGGRIVPRFSELTAEKLGFAGLVQEISFGTTKDKMLVIE 375
+ V+ V +IE + R + TAE + A LV+E++ GT +K + I
Sbjct: 957 KIKCLVVKDVEREDIEFVCKTLHCRPIASLDHFTAENMSSADLVEEVASGT--NKFVKIT 784
Query: 376 QCKN-SRAVTIFIRGGNKMIIEEAKRSLHDALCVIRNLIRDNRVVYGGGAAEISCALAVS 434
+N R V+I RG NK+++EEA RSLHDALCV+R L+R+ + GGGA EI AL ++
Sbjct: 783 GIQNQGRTVSIICRGSNKLVLEEAARSLHDALCVVRCLVRNRAQIVGGGAPEIEMALQLA 604
Query: 435 QEADKCPTLEQYAMRAFADALEVIPMALSENSGMNPIQTMTEVRARQVKEMNPALGIDCL 494
A ++ Y RAFADALEVIP L+EN+G+NPI T+TE+R R + A GI+
Sbjct: 603 AAAQTVDGVDAYCYRAFADALEVIPSTLAENAGLNPIATVTELRNRHAQGEKNA-GINVR 427
Query: 495 HKGTNDMKQQHVIETLIGKKQQISLATQMVRMILKIDDI 533
D+ ++V++ L+ I+LAT+ VR ILKIDDI
Sbjct: 426 KGAITDIFAENVVQPLLVSTSAITLATETVRSILKIDDI 310
>05356
Length = 2339
Score = 107 bits (268), Expect(2) = 4e-48, Method: Compositional matrix adjust.
Identities = 80/283 (28%), Positives = 145/283 (51%), Gaps = 3/283 (1%)
Frame = +2
Query: 22 QDRKSRLMGL-EALKSHIMAAKAVANTMRTSLGPNGLDKMMVDKDGDVTVTNDGATILSM 80
+D GL EA+ +I A K +A T R++ GP+G +KM+++ + VTND ATIL
Sbjct: 236 KDGAKHFSGLDEAVYRNIEACKELAKTTRSAYGPHGQNKMVINHLEKLFVTNDAATILRE 415
Query: 81 MDVDHQIAKLMVELSKSQDDEIGDXXXXXXXXXXXXXXXXXQLLDRGIHPIRIADGYEQA 140
++V H AK++V + Q+ E GD QLL G+ + +GYE A
Sbjct: 416 LEVQHPAAKMLVLAAHQQEQECGDGTNFVLVFAGALLENAEQLLRMGLSVTEVIEGYELA 595
Query: 141 ARVAIEHLDKISDSVLVDIKDTEPLIQTAKTTLGSKVVNSCHRQMAEIAVNAVLTVADME 200
+ A E L K+ + ++++ E + +T++ SK + +A++ +A ++V +
Sbjct: 596 LKKAHEILPKLVIGHVKNLRNKEEVKTAIRTSVMSKQYGN-EDFLADLITDACVSVLPAK 772
Query: 201 RRDVDFEL--IKVEGKVGGRLEDTKLIKGVIVDKDFSHPQMPKKVEDAKIAILTCPFEPP 258
+ F + ++V +G L + I+G++ + KVE AK+A+ TCP +
Sbjct: 773 ---ISFSVDNVRVCKILGCGLLQSSTIQGMVFKRQVEGE--ITKVEKAKVAVFTCPLDSM 937
Query: 259 KPKTKHKLDVTSVEDYKALQKYEKEKFEEMIQQIKETGANLAI 301
+ +TK + + + E+ + K E++ EE I+ IKE G N+ +
Sbjct: 938 QTETKGTVLIKNAEELMSFSKGEEDMMEEQIKGIKEAGVNVIV 1066
Score = 102 bits (254), Expect(2) = 4e-48, Method: Compositional matrix adjust.
Identities = 65/235 (27%), Positives = 120/235 (51%), Gaps = 3/235 (1%)
Frame = +1
Query: 302 CQWG-FDDEANHLLLQNNLPAVRWVGGPEIELIAIATGGRIVPRFSELTAEKLGFAGLVQ 360
C WG D A H + + +R + ++ + + +P+ + E+ G+ LV
Sbjct: 1063 CSWGEVGDLAQHYCNKYKVMVIRLLSKWDLRRLCKSICATALPKVTTPRNEECGYCDLVY 1242
Query: 361 EISFGTTKDKMLVIEQCKNSRAVT-IFIRGGNKMIIEEAKRSLHDALCVIRNLIRDNRVV 419
G T +++ +Q K+ +T + IRG I+++ +R+L D + + L +D+R+V
Sbjct: 1243 VDEIGETP--VVIFQQNKDESPITTVIIRGSTDNIMDDIERALDDGVNTFKALTKDDRLV 1416
Query: 420 YGGGAAEISCALAVSQEADKCPTLEQYAMRAFADALEVIPMALSENSGMNPIQTMTEVRA 479
G GA EI A ++ + P LEQYA++ FA++LEVIP AL+EN+GM ++++ A
Sbjct: 1417 PGAGATEIELAKQITTYGESLPGLEQYAVKKFAESLEVIPRALAENTGMKATDILSKLYA 1596
Query: 480 RQVKEMNPALGIDCLHKGTN-DMKQQHVIETLIGKKQQISLATQMVRMILKIDDI 533
+E G+D G+ D KQ ++ + + + + A +L++D I
Sbjct: 1597 AH-QEGQQNAGVDIDDSGSVLDAKQANLTDLYLNRYWGLKFAAAAACTVLRVDQI 1758
>06409
Length = 1533
Score = 181 bits (458), Expect = 9e-46, Method: Compositional matrix adjust.
Identities = 104/300 (34%), Positives = 169/300 (56%), Gaps = 6/300 (2%)
Frame = -3
Query: 240 PKKVEDAKIAILTCPFEPPKPKTKHKLDVTSVEDYKALQKYEKEKFEEMIQQIKETGANL 299
P KVE AKI + PPK ++++ V+ + + E+ +++++IK+ G N+
Sbjct: 1501 PSKVEKAKIGFIQFCISPPKTDMENQVIVSDYTQMDRVLREERNYILDIVKKIKKAGCNV 1322
Query: 300 AICQWGF-----DDEANHLLLQNNLPAVRWVGGPEIELIAIATGGRIVPRFSELTAEKLG 354
+ Q D A H L + + V+ + ++E + G R V E LG
Sbjct: 1321 LLIQKSILRDAVSDLALHFLAKMKIMVVKDIEREDVEFVCKTLGCRPVASLDHFLPENLG 1142
Query: 355 FAGLVQEISFGTTKDKMLVIEQCKN-SRAVTIFIRGGNKMIIEEAKRSLHDALCVIRNLI 413
A L++E+ G++K ++ N + VT+ IRG NK+++EEA RSLHDALCVIR L+
Sbjct: 1141 SADLIEEVQTGSSK--IVKATGIANPGQTVTVLIRGSNKLVLEEADRSLHDALCVIRCLV 968
Query: 414 RDNRVVYGGGAAEISCALAVSQEADKCPTLEQYAMRAFADALEVIPMALSENSGMNPIQT 473
+ ++ GGGA E ++ ++ A+ +EQY RAFA+ALEVIP L+EN+G+NPI T
Sbjct: 967 KKKALIAGGGAPETEMSMRLAAYANTLAGMEQYCFRAFAEALEVIPFTLAENAGLNPIST 788
Query: 474 MTEVRARQVKEMNPALGIDCLHKGTNDMKQQHVIETLIGKKQQISLATQMVRMILKIDDI 533
+T +R R + A GI+ ++ +++V++ L+ I+LA++ VR ILKIDDI
Sbjct: 787 VTXLRTRHAQGERTA-GINVRKGAITNILEENVLQPLLVSTSAITLASETVRSILKIDDI 611
>02673
Length = 1243
Score = 161 bits (408), Expect = 6e-40, Method: Compositional matrix adjust.
Identities = 80/116 (68%), Positives = 100/116 (86%)
Frame = +1
Query: 423 GAAEISCALAVSQEADKCPTLEQYAMRAFADALEVIPMALSENSGMNPIQTMTEVRARQV 482
GA EI+ ++AV++ ADK TLEQYA+R+F++ALE +P+AL+ENSG+ PIQT+ EV++RQV
Sbjct: 1 GAPEIAASVAVAEAADKISTLEQYAVRSFSEALEAVPLALAENSGLAPIQTLAEVKSRQV 180
Query: 483 KEMNPALGIDCLHKGTNDMKQQHVIETLIGKKQQISLATQMVRMILKIDDIRKPGE 538
KE NP LGIDCL KGTNDMK+Q+VIETL KKQQI LATQ+VRMILKIDDIR P +
Sbjct: 181 KEKNPRLGIDCLLKGTNDMKEQNVIETLTAKKQQILLATQLVRMILKIDDIRAPSD 348
>29631
Length = 1257
Score = 92.4 bits (228), Expect(2) = 7e-29, Method: Compositional matrix adjust.
Identities = 56/190 (29%), Positives = 104/190 (54%), Gaps = 3/190 (1%)
Frame = +1
Query: 168 TAKTTLGSKVVNSCHRQMAEIAVNAVLTVADME--RRDVDFE-LIKVEGKVGGRLEDTKL 224
++++ LG+K ++ +IA++A TV E R+++D + KVE GG +E++++
Sbjct: 451 SSQSCLGTKFISKWMDLACQIALDATTTVFMEENGRKEIDIKRYAKVEKIPGGTMEESEV 630
Query: 225 IKGVIVDKDFSHPQMPKKVEDAKIAILTCPFEPPKPKTKHKLDVTSVEDYKALQKYEKEK 284
+KG+ V+KD H +M +++E+ +I +L C E K ++ ++++ ED+ + + E+E
Sbjct: 631 LKGIXVNKDVVHXKMKRRIENPRIMLLDCNLEYKKGESATNIEISKEEDFAKILQLEEEY 810
Query: 285 FEEMIQQIKETGANLAICQWGFDDEANHLLLQNNLPAVRWVGGPEIELIAIATGGRIVPR 344
+M +I +L I + G D A H LL+ + +R V + IA A G I R
Sbjct: 811 IRKMCDEIIALKPDLVITEKGVSDLAQHFLLKAGISVLRRVRKTDNNRIARACGATIANR 990
Query: 345 FSELTAEKLG 354
EL E +G
Sbjct: 991 TDELKEEDMG 1020
Score = 53.5 bits (127), Expect(2) = 7e-29, Method: Compositional matrix adjust.
Identities = 26/66 (39%), Positives = 43/66 (65%)
Frame = +3
Query: 369 DKMLVIEQCKNSRAVTIFIRGGNKMIIEEAKRSLHDALCVIRNLIRDNRVVYGGGAAEIS 428
D + CK+ +A TI +RG +K I+ E +R+L DA+ V RN++ D + GGGA+E++
Sbjct: 1059 DYFTFLVDCKSPKACTILLRGASKDILAEVERNLQDAMNVARNVMIDPHLCPGGGASEMA 1238
Query: 429 CALAVS 434
A A++
Sbjct: 1239 LAQALN 1256
Score = 77.4 bits (189), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 48/161 (29%), Positives = 81/161 (50%)
Frame = +3
Query: 17 LIIKDQDRKSRLMGLEALKSHIMAAKAVANTMRTSLGPNGLDKMMVDKDGDVTVTNDGAT 76
+I+ +Q+ + R G + +I A K +A+ +RT LGP + KM++D G + +TNDG
Sbjct: 3 IIVLNQNTR-RESGRKVQLGNIAAGKTIADVIRTCLGPKSMLKMLMDPMGGIVMTNDGNA 179
Query: 77 ILSMMDVDHQIAKLMVELSKSQDDEIGDXXXXXXXXXXXXXXXXXQLLDRGIHPIRIADG 136
IL ++V H AK M+E++++QD+E GD Q L++ +HP I
Sbjct: 180 ILREINVQHPAAKSMIEVARTQDEETGDGTKSVIILAGEVLSVAEQFLEQQMHPTVIIAA 359
Query: 137 YEQAARVAIEHLDKISDSVLVDIKDTEPLIQTAKTTLGSKV 177
Y QA +E L + +DI D ++ G ++
Sbjct: 360 YRQALEDTLEVL-RTKICTPIDISDRNQMLNIVTKLSGHQI 479
>09900
Length = 1305
Score = 119 bits (298), Expect = 3e-27, Method: Compositional matrix adjust.
Identities = 78/291 (26%), Positives = 143/291 (49%), Gaps = 1/291 (0%)
Frame = +3
Query: 247 KIAILTCPFEPPKPKTKHKLDVTSVEDYKALQKYEKEKFEEMIQQIKETGANLAICQWGF 306
+IA+L E + ++ V +V++Y+++ E + + + +I ++GA + + +
Sbjct: 60 RIALLNIELELKSERDNAEVRVDNVQEYQSIVDAEWKILYDKLDKIHQSGAKVVLSKLPI 239
Query: 307 DDEANHLLLQNNLPAVRWVGGPEIELIAIATGGRIVPRFSELTAEKLGFAGLVQEISFGT 366
D A ++ V ++ A GG I LT + LG L EI G
Sbjct: 240 GDVATQYFADRDMFCAGRVPEEDLRRTMKACGGSIQTTVQSLTPDVLGTCQLFDEIQIGG 419
Query: 367 TKDKMLVIEQCKNSRAVTIFIRGGNKMIIEEAKRSLHDALCVIRNLIRDNRVVYGGGAAE 426
+ M + C +R TI +RGG + +EE +RSLHDA+ ++R I+++ VV GGGA E
Sbjct: 420 ERFNMF--KGCTMARTCTIILRGGAEQFMEETERSLHDAIMIVRRAIKNDSVVAGGGAIE 593
Query: 427 ISCALAVSQEADKCPTLEQYAMRAFADALEVIPMALSENSGMNPIQTMTEVRARQVKEMN 486
+ + + + + EQ M A+A ALEVIP L +N+G + + ++R + +
Sbjct: 594 MEVSYHLREHSHTIAGKEQLLMSAYAKALEVIPRQLCDNAGFDATNILNKLRQKHAQG-G 770
Query: 487 PALGIDCLHKGTNDMKQQHVIETLIGKKQQISLATQMVRMILKIDD-IRKP 536
G++ L + D + V E + K ++ A++ +IL +D+ I+ P
Sbjct: 771 TWYGVNILREDIADNFEDCVWEPAVVKINALTAASEATALILSVDETIKNP 923
>29864
Length = 1026
Score = 107 bits (267), Expect = 1e-23, Method: Compositional matrix adjust.
Identities = 78/251 (31%), Positives = 123/251 (49%)
Frame = +1
Query: 32 EALKSHIMAAKAVANTMRTSLGPNGLDKMMVDKDGDVTVTNDGATILSMMDVDHQIAKLM 91
+AL +I AAK + + +R++LGP G KM+V GD+ +T DG +L M + H A L+
Sbjct: 160 QALAVNIAAAKGLQDVLRSNLGPKGTMKMLVSGAGDIKLTKDGNVLLHEMQIQHPTASLI 339
Query: 92 VELSKSQDDEIGDXXXXXXXXXXXXXXXXXQLLDRGIHPIRIADGYEQAARVAIEHLDKI 151
++ +QDD GD + G+HP I +G+E A A+E L+++
Sbjct: 340 ARVATAQDDITGDGTTSNVLIIGELLKQADLYIAEGLHPRLITEGFELARNKALEVLEEV 519
Query: 152 SDSVLVDIKDTEPLIQTAKTTLGSKVVNSCHRQMAEIAVNAVLTVADMERRDVDFELIKV 211
V D E L+Q A+T+L +KV + E V+AVL + +D ++++
Sbjct: 520 KVKREV---DRETLVQVARTSLRTKVHTELADLLTEHVVDAVLAI-QXPGEGIDLHMVEL 687
Query: 212 EGKVGGRLEDTKLIKGVIVDKDFSHPQMPKKVEDAKIAILTCPFEPPKPKTKHKLDVTSV 271
D+ L++G+++D HP M K +DA ILTC KT +V S
Sbjct: 688 MEMQHKTDLDSTLVRGLVMDHGARHPDMKKHTKDA--FILTCNVSLEYEKT----EVNSG 849
Query: 272 EDYKALQKYEK 282
YK Q+ EK
Sbjct: 850 FFYKTAQEREK 882
>33770
Length = 484
Score = 96.7 bits (239), Expect = 2e-20, Method: Compositional matrix adjust.
Identities = 67/163 (41%), Positives = 97/163 (59%), Gaps = 1/163 (0%)
Frame = +1
Query: 59 KMMVDKDGDVTVTNDGATILSMMDVDHQIAKLMVELSKSQDDEIGDXXXXXXXXXXXXXX 118
KM+ +GDVT+TNDGATIL M V H AK++VELSK+QD E GD
Sbjct: 1 KMIQAANGDVTITNDGATILKQMQVLHPAAKMLVELSKAQDIEXGDGTTTVVVLAGSLLD 180
Query: 119 XXXQLLDRGIHPIRIADGYEQAARVAIEHLDKISDSVLVDIKDTEPLIQTAKTTLGSKVV 178
+LL +GIHP I++ +++AA +E LD + +++ D E L+ +A T+L SKVV
Sbjct: 181 ASAKLLAKGIHPTMISEAFQKAASKCVELLDGMVKP--LELSDRESLLSSASTSLNSKVV 354
Query: 179 NSCHRQMAEIAVNAVLTVAD-MERRDVDFELIKVEGKVGGRLE 220
+ +A IAV+AVL V D +VD + IK+ K+GG ++
Sbjct: 355 SQYSSMLAPIAVDAVLKVIDPATATNVDLKDIKIIKKLGGTID 483
>30661
Length = 380
Score = 85.9 bits (211), Expect = 4e-17, Method: Compositional matrix adjust.
Identities = 48/114 (42%), Positives = 64/114 (56%)
Frame = +3
Query: 338 GGRIVPRFSELTAEKLGFAGLVQEISFGTTKDKMLVIEQCKNSRAVTIFIRGGNKMIIEE 397
GG I F KLG L++E+ G +DK++ A TI +RG + I++E
Sbjct: 30 GGEITSTFDCPEKTKLGQCDLIEEVMIG--EDKLIKFSGVALGEACTIVLRGATQQILDE 203
Query: 398 AKRSLHDALCVIRNLIRDNRVVYGGGAAEISCALAVSQEADKCPTLEQYAMRAF 451
A RSLHDALCV+ +++ R VYGGG +E+ A AVSQ A K P E AM A
Sbjct: 204 AXRSLHDALCVLSQTVKETRTVYGGGCSEMLMAEAVSQLAAKTPGKEAIAMEAL 365
>10291
Length = 1066
Score = 70.9 bits (172), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 35/49 (71%), Positives = 41/49 (83%)
Frame = +1
Query: 490 GIDCLHKGTNDMKQQHVIETLIGKKQQISLATQMVRMILKIDDIRKPGE 538
G+ C +GTNDMK+Q+VIETL KKQQI LATQ+VRMILKIDDIR P +
Sbjct: 13 GVGC--RGTNDMKEQNVIETLTAKKQQILLATQLVRMILKIDDIRAPSD 153
>17249
Length = 909
Score = 47.4 bits (111), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 29/80 (36%), Positives = 41/80 (51%)
Frame = +3
Query: 454 ALEVIPMALSENSGMNPIQTMTEVRARQVKEMNPALGIDCLHKGTNDMKQQHVIETLIGK 513
ALEVI L +N G N I+T+T +RA+ + GID DM + + E L K
Sbjct: 12 ALEVISRTLIQNCGANTIRTLTALRAKHAQGQKNTWGIDGNTGNIVDMAEFGIWEPLSVK 191
Query: 514 KQQISLATQMVRMILKIDDI 533
Q A + ++L+IDDI
Sbjct: 192 LQVYKTACETAILLLRIDDI 251
>29327
Length = 2425
Score = 32.3 bits (72), Expect = 0.55, Method: Compositional matrix adjust.
Identities = 15/45 (33%), Positives = 27/45 (60%)
Frame = +1
Query: 489 LGIDCLHKGTNDMKQQHVIETLIGKKQQISLATQMVRMILKIDDI 533
L + ++ +++V++ L+ I+LA++ VR ILKIDDI
Sbjct: 145 LNV*LFQGAITNILEENVLQPLLVSTSAITLASETVRSILKIDDI 279
>09856
Length = 1154
Score = 30.4 bits (67), Expect = 2.1, Method: Compositional matrix adjust.
Identities = 17/45 (37%), Positives = 22/45 (48%), Gaps = 2/45 (4%)
Frame = -2
Query: 242 KVEDAKIAILTCPFEPPKPKTKHKLDVTSVEDYKALQK--YEKEK 284
KV D+ I I TC F P + H + + +DY L YEK K
Sbjct: 163 KVMDSFIVIKTCMFFPLQH*NDHNYQLNTTQDYNFLGNITYEKTK 29
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000290158 | hsapiens_gene_ensembl | Importin
subunit beta-1 (Karyopherin subunit beta-1) (Nuclear factor P97)
(Importin 90). [Source:Uniprot/SWISSPROT;Acc:Q14974]
(876 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
09672 765 0.0
15415 31 2.2
10618 30 5.7
>09672
Length = 1963
Score = 765 bits (1975), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 366/526 (69%), Positives = 440/526 (83%), Gaps = 1/526 (0%)
Frame = -2
Query: 350 VCLMLLATCCEDDIVPHVLPFIKEHIKNPDWRYRDAAVMAFGCILEGPEPSQLKPLVIQA 409
VCLML+ATCCEDD+VPHVLPF+KE+I++ DWRYRDAAVMAFG ILEGP+ +LKP+V QA
Sbjct: 1962 VCLMLMATCCEDDVVPHVLPFVKENIRHADWRYRDAAVMAFGSILEGPDSEKLKPIVEQA 1783
Query: 410 MPTLIELMKDPSVVVRDTAAWTVGRICELLPEAAINDVYLAPLLQCLIEGLSAEPRVASN 469
MP LIEL+ DPSVVVRDTAAWTVGR+CE+LPEA IN+ L PLL LI+GL AEPRVASN
Sbjct: 1782 MPMLIELLTDPSVVVRDTAAWTVGRVCEMLPEAVINENCLNPLLGALIKGLEAEPRVASN 1603
Query: 470 VCWAFSSLXXXXXXXXXXXXXXXXXXTYCLSSSFELIVQKLLETTDRPDGHQNNLRSSAY 529
+CWAFSSL TYCLSS FE +VQ+LLETTDR DG+Q+NLR++AY
Sbjct: 1602 ICWAFSSLAEAAYESADTADEISEPETYCLSSYFETMVQRLLETTDRTDGNQHNLRNAAY 1423
Query: 530 ESLMEIVKNSAKDCYPAVQKTTLVIMERLQQVLQMESHIQSTSDRIQFNDLQSLLCATLQ 589
E+LME+VKNS KDCY VQKTT++I+ERL++VL ME+ IQST+DR+Q+NDLQSLLCATLQ
Sbjct: 1422 EALMELVKNSPKDCYLIVQKTTVIILERLERVLGMEAAIQSTNDRVQYNDLQSLLCATLQ 1243
Query: 590 NVLRKVQHQDALQISDVVMASLLRMFQSTAG-SGGVQEDALMAVSTLVEVLGGEFLKYME 648
+V+RK+ +DA +ISD +M SLL MFQ+T+G +G VQEDAL+AVSTL EVLG F KY+E
Sbjct: 1242 SVVRKMTPEDAPKISDQIMTSLLSMFQNTSGKAGNVQEDALVAVSTLCEVLGDNFEKYLE 1063
Query: 649 AFKPFLGIGLKNYAEYQVCLAAVGLVGDLCRALQSNIIPFCDEVMQLLLENLGNENVHRS 708
AFKP+L +GLKNYAEYQVCLAAVGL+GD+CRAL ++PFC+E+M +LL+NLGNE+VHRS
Sbjct: 1062 AFKPYLLVGLKNYAEYQVCLAAVGLIGDMCRALGLKMLPFCNELMMVLLDNLGNESVHRS 883
Query: 709 VKPQILSVFGDIALAIGGEFKKYLEVVLNTLQQASQAQVDKSDYDMVDYLNELRESCLEA 768
VKPQILSVFGD+ALAIG FK YLEVVL TLQQASQAQVDK+DYDM+DYLNELRE CLEA
Sbjct: 882 VKPQILSVFGDVALAIGPNFKPYLEVVLTTLQQASQAQVDKTDYDMIDYLNELREGCLEA 703
Query: 769 YTGIVQGLKGDQENVHPDVMLVQPRVEFILSFIDHIAGDEDHTDGVVACAAGLIGDLCTA 828
YTGIVQGLKGD E + PDV L+QP V I+SFI+HI+ DED +D +A GL+GDLCTA
Sbjct: 702 YTGIVQGLKGDAEVLSPDVNLLQPHVAHIISFIEHISMDEDKSDSNIAACCGLLGDLCTA 523
Query: 829 FGKDVLKLVEARPMIHELLTEGRRSKTNKAKTLATWATKELRKLKN 874
F ++ ++E + +I LLT+GRRSK KAKTLATWATKE+RK+KN
Sbjct: 522 FSMSIMPMLE-KDVIQNLLTQGRRSKVQKAKTLATWATKEIRKMKN 388
>15415
Length = 392
Score = 30.8 bits (68), Expect = 2.2, Method: Composition-based stats.
Identities = 17/45 (37%), Positives = 25/45 (55%)
Frame = +1
Query: 653 FLGIGLKNYAEYQVCLAAVGLVGDLCRALQSNIIPFCDEVMQLLL 697
F +G+ +Y E + + VG A QSNIIPF D +++LL
Sbjct: 166 FF*LGINSYPEMSISMDIVGET----EATQSNIIPFTDVNLRVLL 288
>10618
Length = 906
Score = 29.6 bits (65), Expect = 5.7, Method: Compositional matrix adjust.
Identities = 19/71 (26%), Positives = 32/71 (45%), Gaps = 10/71 (14%)
Frame = -2
Query: 106 PSSASQCVAGIA--------CAEIPV--NQWPELIPQLVANVTNPNSTEHMKESTLEAIG 155
PS S CV + CAEIPV QW ++ +A V + + E +++
Sbjct: 668 PSFQSGCVKILGMT*KHTAMCAEIPVMCRQWVKMSSSFMAKVCPQKTVLNFSEKAFKSL* 489
Query: 156 YICQDIDPEQL 166
+C+ ID ++
Sbjct: 488 KVCKFIDENRV 456
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000301071 | hsapiens_gene_ensembl | Tubulin
alpha-1A chain (Tubulin B-alpha-1) (Tubulin alpha-3 chain)
(Alpha-tubulin 3). [Source:Uniprot/SWISSPROT;Acc:Q71U36]
(451 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
00276 686 0.0
12457 460 e-134
06360 341 4e-94
03702 282 2e-76
17215 244 6e-65
16482 214 5e-56
13181 184 6e-47
04882 172 2e-43
05902 137 8e-33
25015 115 4e-26
39157 96 3e-20
28905 91 1e-18
31457 87 2e-17
26304 29 4.7
>00276
Length = 1330
Score = 686 bits (1769), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 328/353 (92%), Positives = 335/353 (94%)
Frame = -3
Query: 80 TGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFH 139
TGTYRQL PEQL+TGKEDAANNYARGHYTIGKE++DLVLDRIRKLADQCTGLQGFL+FH
Sbjct: 1328 TGTYRQL-SPEQLVTGKEDAANNYARGHYTIGKELVDLVLDRIRKLADQCTGLQGFLIFH 1152
Query: 140 XXXXXXXXXXXXLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSD 199
L MERLSVDYGKKSKLEF IYPAPQVSTAVVEPYNSILTTHTTLEHSD
Sbjct: 1151 SFGGGTGSGFTSLXMERLSVDYGKKSKLEFXIYPAPQVSTAVVEPYNSILTTHTTLEHSD 972
Query: 200 CAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNL 259
CAFMVDNEAIYDICRRNLDIERPTYTNLNRLI QIVSSITASLRFDGALNVDLTEFQTNL
Sbjct: 971 CAFMVDNEAIYDICRRNLDIERPTYTNLNRLIXQIVSSITASLRFDGALNVDLTEFQTNL 792
Query: 260 VPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLY 319
VPYPRIHFPLATYAPVISAEKAYHEQL VAEITNACFEPANQ+VKCDPRHGKYMACC+LY
Sbjct: 791 VPYPRIHFPLATYAPVISAEKAYHEQLXVAEITNACFEPANQLVKCDPRHGKYMACCMLY 612
Query: 320 RGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLS 379
RGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLS
Sbjct: 611 RGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLS 432
Query: 380 NTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDY 432
NTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEARED+AALEKDY
Sbjct: 431 NTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDY 273
>12457
Length = 781
Score = 460 bits (1183), Expect(2) = e-134, Method: Compositional matrix adjust.
Identities = 220/239 (92%), Positives = 226/239 (94%)
Frame = -1
Query: 67 FVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLA 126
VDLEPTV+DEVRTGTYRQLFHPEQL+TGKEDAANNYARGHYTIGKEI+DLVLDRIRKLA
Sbjct: 718 LVDLEPTVVDEVRTGTYRQLFHPEQLVTGKEDAANNYARGHYTIGKEIVDLVLDRIRKLA 539
Query: 127 DQCTGLQGFLVFHXXXXXXXXXXXXLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYN 186
DQCTGLQGFL+FH LLMERLSVDYGKKSKLEF+IYPAPQVSTAVVEPYN
Sbjct: 538 DQCTGLQGFLIFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFAIYPAPQVSTAVVEPYN 359
Query: 187 SILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDG 246
SILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDG
Sbjct: 358 SILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDG 179
Query: 247 ALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKC 305
ALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQL+VAEITNACFEPANQMVKC
Sbjct: 178 ALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLTVAEITNACFEPANQMVKC 2
Score = 38.1 bits (87), Expect(2) = e-134, Method: Compositional matrix adjust.
Identities = 20/28 (71%), Positives = 20/28 (71%)
Frame = -2
Query: 45 GDDSFNTFFSETGAGKHVPRAVFVDLEP 72
GDDSF T SETGAGKHVPRAV P
Sbjct: 780 GDDSF-TPLSETGAGKHVPRAVSSXXSP 700
>06360
Length = 1896
Score = 341 bits (874), Expect = 4e-94, Method: Compositional matrix adjust.
Identities = 159/178 (89%), Positives = 166/178 (93%)
Frame = -1
Query: 1 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGK 60
MRECIS+HVGQAGVQ+GNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGK
Sbjct: 1710 MRECISVHVGQAGVQMGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGK 1531
Query: 61 HVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLD 120
HVPRAVFVDLEPTV+DEVRTGTYRQLFHPEQL+TGKEDAANNYARGHYTIGKEI+DLVLD
Sbjct: 1530 HVPRAVFVDLEPTVVDEVRTGTYRQLFHPEQLVTGKEDAANNYARGHYTIGKEIVDLVLD 1351
Query: 121 RIRKLADQCTGLQGFLVFHXXXXXXXXXXXXLLMERLSVDYGKKSKLEFSIYPAPQVS 178
RIRKLADQCTGLQGFL+FH LLMERLSVDYGKKSKLEF+IYPAPQVS
Sbjct: 1350 RIRKLADQCTGLQGFLIFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFAIYPAPQVS 1177
>03702
Length = 1932
Score = 282 bits (721), Expect = 2e-76, Method: Compositional matrix adjust.
Identities = 138/153 (90%), Positives = 142/153 (92%)
Frame = +1
Query: 155 ERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICR 214
ERLSVDYGKKSKLEF+IYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICR
Sbjct: 1459 ERLSVDYGKKSKLEFAIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICR 1638
Query: 215 RNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAP 274
RNLDIERP YTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVP P P P
Sbjct: 1639 RNLDIERPXYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVPTPH-PLPPGHLCP 1815
Query: 275 VISAEKAYHEQLSVAEITNACFEPANQMVKCDP 307
VISAEKAYHEQL+VAE+TNACFEPANQ+VKCDP
Sbjct: 1816 VISAEKAYHEQLTVAEVTNACFEPANQLVKCDP 1914
>17215
Length = 632
Score = 244 bits (622), Expect = 6e-65, Method: Compositional matrix adjust.
Identities = 114/116 (98%), Positives = 116/116 (100%)
Frame = +3
Query: 317 LLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVC 376
+LYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVC
Sbjct: 3 MLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVC 182
Query: 377 MLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDY 432
MLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEARED+AALEKDY
Sbjct: 183 MLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDY 350
>16482
Length = 837
Score = 214 bits (545), Expect = 5e-56, Method: Compositional matrix adjust.
Identities = 105/248 (42%), Positives = 149/248 (60%)
Frame = +1
Query: 1 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGK 60
MRE + + GQ G QIG WE+ EHGI P G D + + N +++E GK
Sbjct: 100 MREIVHMQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQL--ERINVYYNEATGGK 273
Query: 61 HVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLD 120
+VPRAV VDLEP +D VR+G + Q+F P+ + G+ A NN+A+GHYT G E++D VLD
Sbjct: 274 YVPRAVLVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLD 453
Query: 121 RIRKLADQCTGLQGFLVFHXXXXXXXXXXXXLLMERLSVDYGKKSKLEFSIYPAPQVSTA 180
+RK A+ C LQGF + H LL+ ++ +Y + FS+ P+P+VS
Sbjct: 454 VVRKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDT 633
Query: 181 VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITA 240
VVEPYN+ L+ H +E++D + +DNEA+YDIC R L + PTY +LN L+ +S +T
Sbjct: 634 VVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTT 813
Query: 241 SLRFDGAL 248
LRF G L
Sbjct: 814 CLRFPGQL 837
>13181
Length = 1092
Score = 184 bits (467), Expect = 6e-47, Method: Compositional matrix adjust.
Identities = 83/223 (37%), Positives = 128/223 (57%)
Frame = -3
Query: 210 YDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPL 269
YDIC R L + PTY +LN L+ +S +T LRF G LN DL + N+VP+PR+HF +
Sbjct: 1090 YDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFM 911
Query: 270 ATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVN 329
+AP+ S + L+V E+T F+ N M CDPRHG+Y+ ++RG + K+V+
Sbjct: 910 PGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAMFRGRMSMKEVD 731
Query: 330 AAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWA 389
+ ++ K + FV+W P K + PP ++ + + N+TAI E +
Sbjct: 730 EQMLNVQNKNSSYFVEWIPNNVKTAVCDIPP--------RGLKMSATFVGNSTAIQELFK 575
Query: 390 RLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDY 432
R+ +F M+ ++AF+HWY GEGM+E EF+EA +M L +Y
Sbjct: 574 RISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEY 446
>04882
Length = 1136
Score = 172 bits (437), Expect = 2e-43, Method: Compositional matrix adjust.
Identities = 77/214 (35%), Positives = 122/214 (57%)
Frame = +2
Query: 219 IERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISA 278
+ PTY +LN L+ +S +T LRF G LN DL + N+VP+PR+HF + +AP+ S
Sbjct: 314 VHTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSR 493
Query: 279 EKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTK 338
+ L+V E+T F+ N M CDPRHG+Y+ ++RG + K+V+ + ++ K
Sbjct: 494 GSQQYRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNK 673
Query: 339 RTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLM 398
+ FV+W P K + PP ++ + + N+TAI E + R+ +F M
Sbjct: 674 NSSYFVEWIPNNVKTAVCDIPPR--------GLKMSATFIGNSTAIQELFKRISEQFTAM 829
Query: 399 YAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDY 432
+ ++AF+HWY GEGM+E EF+EA +M L +Y
Sbjct: 830 FRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEY 931
>05902
Length = 1127
Score = 137 bits (345), Expect = 8e-33, Method: Compositional matrix adjust.
Identities = 81/289 (28%), Positives = 158/289 (54%), Gaps = 9/289 (3%)
Frame = +2
Query: 153 LMERLSVDYGKKSKLEFSIYP-APQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYD 211
L+E+L+ + KK +S++P ++S VV+PYNS+LT +++DC ++DN A+
Sbjct: 65 LLEKLNDRFPKKLIQTYSVFPNVDEISDVVVQPYNSLLTLKRLTQNADCVVVLDNTALNR 244
Query: 212 ICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLAT 271
I L I+ PT+ +N+L+ ++S+ T +LR+ G +N DL +L+P PR+HF +
Sbjct: 245 IAADRLHIDTPTFAQVNQLVSTVMSTSTTTLRYPGYMNNDLIGLIASLIPTPRLHFLMTG 424
Query: 272 YAPVIS-AEKAYHEQLSVAEITNACFEPANQMVKCDPRHGK----YMACCLLYRGDVVPK 326
Y P+ + ++ A + +V ++ +P N MV P H + Y++ + +G+V P
Sbjct: 425 YTPLTTDSQVANVRKTTVLDVMRRLLQPKNMMVST-PVHRQANHCYISILNIIQGEVDPT 601
Query: 327 DVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAE 386
V+ ++ I+ ++ QF+ W P +V ++ + P V ++ + ML+N T+I+
Sbjct: 602 QVHKSLQRIRERKLAQFIPWGPASIQVALSRKSPYVQTAHRVSGL-----MLANHTSISH 766
Query: 387 AWARLDHKFDLMYAKRAFVHWYVGEGMEE---GEFSEAREDMAALEKDY 432
+ R+ ++D + + AF+ + E + + EF +RE + L +Y
Sbjct: 767 LFERILRQYDKLRKREAFMDQFKKEAIFKDNLDEFDNSREALQLLVDEY 913
>25015
Length = 458
Score = 115 bits (287), Expect = 4e-26, Method: Compositional matrix adjust.
Identities = 54/119 (45%), Positives = 75/119 (63%)
Frame = -3
Query: 21 WELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRT 80
WE+ EHGI P G D + + N +++E GK+VPRAV VDLEP +D VR+
Sbjct: 360 WEVISDEHGIDPTGTYHGDSDLQ--LERINVYYNEATGGKYVPRAVLVDLEPGTMDSVRS 187
Query: 81 GTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFH 139
G + Q+F P+ + G+ A NN+A+GHYT G E++D VLD +RK A+ C LQGF + H
Sbjct: 186 GPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQLTH 10
>39157
Length = 488
Score = 95.9 bits (237), Expect = 3e-20, Method: Compositional matrix adjust.
Identities = 51/127 (40%), Positives = 73/127 (57%), Gaps = 3/127 (2%)
Frame = -1
Query: 1 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGK 60
MRE + + GQ G QIG WE+ EHGI P G D + + N +++E GK
Sbjct: 443 MREIVHLQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQ--LERINVYYNEATGGK 270
Query: 61 HVPRAVFVDLEPTVIDEVRTGT--YRQLFHPEQLITGKEDAANNYARGHYTI-GKEIIDL 117
+VPRAV VDLEP +D VR+G+ ++F P+ + G+ A NN+ + T G E++D
Sbjct: 269 YVPRAVLVDLEPGTMDSVRSGSPFGPKIFRPDNFVFGQSGAGNNWGQKDTTQRGAELVDS 90
Query: 118 VLDRIRK 124
VLD +RK
Sbjct: 89 VLDVVRK 69
>28905
Length = 425
Score = 90.5 bits (223), Expect = 1e-18, Method: Composition-based stats.
Identities = 36/103 (34%), Positives = 59/103 (57%)
Frame = -1
Query: 258 NLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCL 317
N+VP+PR+HF + +AP+ S + L+V E+T F+ N M CDPRHG+Y+
Sbjct: 380 NMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAA 201
Query: 318 LYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPP 360
++RG + K+V+ + ++ K + FV+W P K + PP
Sbjct: 200 MFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPP 72
>31457
Length = 1530
Score = 86.7 bits (213), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 39/122 (31%), Positives = 67/122 (54%)
Frame = +3
Query: 311 KYMACCLLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAK 370
KY+ ++RG + K+V+ + ++ K + FV+W P K + PP
Sbjct: 234 KYLTVAAMFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPR--------G 389
Query: 371 VQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEK 430
++ + + N+TAI E + R+ +F M+ ++AF+HWY GEGM+E EF+EA +M L
Sbjct: 390 LKMSSTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS 569
Query: 431 DY 432
+Y
Sbjct: 570 EY 575
>26304
Length = 1290
Score = 28.9 bits (63), Expect = 4.7, Method: Compositional matrix adjust.
Identities = 13/27 (48%), Positives = 18/27 (66%)
Frame = -2
Query: 106 GHYTIGKEIIDLVLDRIRKLADQCTGL 132
G T+GK I DL L++IR ++ QC L
Sbjct: 1103 GGSTLGKFIFDLQLNQIRNISLQCESL 1023
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000318297 | hsapiens_gene_ensembl | RuvB-like 1
(EC 3.6.1.-) (49 kDa TATA box-binding protein-interacting protein) (49
kDa TBP-interacting protein) (TIP49a) (Pontin 52) (Nuclear matrix
protein 238) (NMP 238) (54 kDa erythrocyte cytosolic protein) (ECP-54)
(TIP60-associated protein 54-alpha)
[Source:Uniprot/SWISSPROT;Acc:Q9Y265]
(456 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
01279 384 0.0
14389 315 2e-86
23413 177 6e-45
39786 45 6e-12
20270 40 0.002
23766 39 0.003
07243 37 0.020
19129 37 0.023
01642 37 0.024
17843 36 0.025
03022 35 0.076
19561 34 0.14
26408 33 0.23
27434 33 0.26
09184 29 4.4
15498 29 4.6
01586 29 4.8
30094 28 8.7
>01279
Length = 2183
Score = 384 bits (987), Expect(3) = 0.0, Method: Compositional matrix adjust.
Identities = 176/227 (77%), Positives = 209/227 (92%)
Frame = -2
Query: 230 KKKEIIQDVTLHDLDVANARPQGGQDILSMMGQLMKPKKTEITDKLRGEINKVVNKYIDQ 289
+KKE+IQDVTLHDLDVANARPQGGQDI+SMMGQLMKPKKTEITDKLR EINKVVNKYIDQ
Sbjct: 1417 QKKEVIQDVTLHDLDVANARPQGGQDIMSMMGQLMKPKKTEITDKLRKEINKVVNKYIDQ 1238
Query: 290 GIAELVPGVLFVDEVHMLDIECFTYLHRALESSIAPIVIFASNRGNCVIRGTEDITSPHG 349
GIAELVPGVLF+DEVHMLDIECFTYLHRALES+IAPIVIFA+NRG C I+GTEDI SPHG
Sbjct: 1237 GIAELVPGVLFIDEVHMLDIECFTYLHRALESTIAPIVIFATNRGKCTIKGTEDIISPHG 1058
Query: 350 IPLDLLDRVMIIRTMLYTPQEMKQIIKIRAQTEGINISEEALNHLGEIGTKTTLRYSVQL 409
+P+DLLDRVMI+RT+ Y+ +EM QI++IR+QTE I + EE++ HLG IG +TTLRY+VQL
Sbjct: 1057 MPMDLLDRVMIVRTLPYSQEEMTQILQIRSQTENIQVEEESIQHLGNIGVRTTLRYAVQL 878
Query: 410 LTPANLLAKINGKDSIEKEHVEEISELFYDAKSSAKILADQQDKYMK 456
LTP ++LA+INGKD++ KE +EEI +LF+DAK+SAKIL +Q+DKY+K
Sbjct: 877 LTPGSILARINGKDNVGKEEIEEIDKLFFDAKASAKILQEQEDKYLK 737
Score = 381 bits (979), Expect(3) = 0.0, Method: Compositional matrix adjust.
Identities = 185/211 (87%), Positives = 201/211 (95%)
Frame = -3
Query: 22 KGLGLDESGLAKQAASGLVGQENAREACGVIVELIKSKKMAGRAVLLAGPPGTGKTALAL 81
KG+ E+G A Q+++GLVGQE AREA GV+VELIK+KKMAGRAVLLAGPPGTGKTA+AL
Sbjct: 2040 KGIRTCENGYAIQSSAGLVGQEGAREAAGVVVELIKTKKMAGRAVLLAGPPGTGKTAIAL 1861
Query: 82 AIAQELGSKVPFCPMVGSEVYSTEIKKTEVLMENFRRAIGLRIKETKEVYEGEVTELTPC 141
AIAQELG+KVPFCPMVGSEVYS+EIKKTEVLMENFRRAIGLRIKETKEVYEGEVTELTP
Sbjct: 1860 AIAQELGNKVPFCPMVGSEVYSSEIKKTEVLMENFRRAIGLRIKETKEVYEGEVTELTPV 1681
Query: 142 ETENPMGGYGKTISHVIIGLKTAKGTKQLKLDPSIFESLQKERVEAGDVIYIEANSGAVK 201
ETENPMGGYGKT+SHV+IGLKTAKGTKQLKLDPSI+ESLQKE+VE GDVIYIEANSGAVK
Sbjct: 1680 ETENPMGGYGKTVSHVVIGLKTAKGTKQLKLDPSIYESLQKEKVEVGDVIYIEANSGAVK 1501
Query: 202 RQGRCDTYATEFDLEAEEYVPLPKGDVHKKK 232
RQGR D+YATEFDLEAEEYVPLPKGDVHK+K
Sbjct: 1500 RQGRSDSYATEFDLEAEEYVPLPKGDVHKRK 1408
Score = 23.5 bits (49), Expect(3) = 0.0, Method: Compositional matrix adjust.
Identities = 11/11 (100%), Positives = 11/11 (100%)
Frame = -2
Query: 1 MKIEEVKSTTK 11
MKIEEVKSTTK
Sbjct: 2101 MKIEEVKSTTK 2069
Score = 36.2 bits (82), Expect = 0.026, Method: Compositional matrix adjust.
Identities = 16/21 (76%), Positives = 18/21 (85%)
Frame = -1
Query: 11 KTQRIASHSHVKGLGLDESGL 31
K QRIASHSHVKGLGL + G+
Sbjct: 2072 KAQRIASHSHVKGLGLAKMGM 2010
>14389
Length = 790
Score = 315 bits (808), Expect = 2e-86, Method: Compositional matrix adjust.
Identities = 150/167 (89%), Positives = 162/167 (97%)
Frame = +3
Query: 74 TGKTALALAIAQELGSKVPFCPMVGSEVYSTEIKKTEVLMENFRRAIGLRIKETKEVYEG 133
TGKTA+ALAIAQELG+KVPFCPMVGSEV+S EIKKTEVLMENFRR+IGLRI+ETKEVYEG
Sbjct: 3 TGKTAIALAIAQELGNKVPFCPMVGSEVFSNEIKKTEVLMENFRRSIGLRIRETKEVYEG 182
Query: 134 EVTELTPCETENPMGGYGKTISHVIIGLKTAKGTKQLKLDPSIFESLQKERVEAGDVIYI 193
EVTELTP ETENPMGGYGKTIS+V+IGLKTAKGTKQLKLDPSIF++LQKE+VE GDVIYI
Sbjct: 183 EVTELTPVETENPMGGYGKTISNVVIGLKTAKGTKQLKLDPSIFDALQKEKVEVGDVIYI 362
Query: 194 EANSGAVKRQGRCDTYATEFDLEAEEYVPLPKGDVHKKKEIIQDVTL 240
EANSGAVKRQGR DT+ATEFDLE EEYVPLPKGDVHKKKE+IQDVTL
Sbjct: 363 EANSGAVKRQGRSDTFATEFDLETEEYVPLPKGDVHKKKEVIQDVTL 503
Score = 102 bits (255), Expect = 2e-22, Method: Compositional matrix adjust.
Identities = 51/116 (43%), Positives = 82/116 (70%), Gaps = 5/116 (4%)
Frame = +3
Query: 343 DITSPHGIPL---DLLDRVMIIR--TMLYTPQEMKQIIKIRAQTEGINISEEALNHLGEI 397
D+ + +PL D+ + +I+ T+LY+ +M+QIIK+RAQTEG+ + E A + L EI
Sbjct: 423 DLETEEYVPLPKGDVHKKKEVIQDVTLLYSTSDMEQIIKLRAQTEGLQLEENAFSRLSEI 602
Query: 398 GTKTTLRYSVQLLTPANLLAKINGKDSIEKEHVEEISELFYDAKSSAKILADQQDK 453
GT +TLRY+VQLLTPA + K+NG++ I K+ ++++ LF DAK S+K L+++ +K
Sbjct: 603 GTSSTLRYAVQLLTPAYQMCKVNGRNLISKDDIDDVHSLFLDAKRSSKHLSEKNNK 770
>23413
Length = 2343
Score = 177 bits (450), Expect = 6e-45, Method: Compositional matrix adjust.
Identities = 83/170 (48%), Positives = 123/170 (72%)
Frame = -3
Query: 286 YIDQGIAELVPGVLFVDEVHMLDIECFTYLHRALESSIAPIVIFASNRGNCVIRGTEDIT 345
+ ++G AE+VPGVLF+DEVHMLDIECF++L+RALE+ +AP++I A+NRG IRGT +
Sbjct: 2341 WREEGKAEIVPGVLFIDEVHMLDIECFSFLNRALETDMAPVLIMATNRGITRIRGTHYM- 2165
Query: 346 SPHGIPLDLLDRVMIIRTMLYTPQEMKQIIKIRAQTEGINISEEALNHLGEIGTKTTLRY 405
SPHG+P+DLLDR++II T Y +E+KQI+KIR + E + +S++AL L +IG + +LRY
Sbjct: 2164 SPHGVPIDLLDRLLIISTTPYDEKEIKQILKIRCEEEDVEMSDDALTVLTKIGVEASLRY 1985
Query: 406 SVQLLTPANLLAKINGKDSIEKEHVEEISELFYDAKSSAKILADQQDKYM 455
S+QL+T ANL+ + +E E ++ + LF D S + L + Q +M
Sbjct: 1984 SIQLITAANLVCRKRKGTEVEMEDIKRVYSLFLDESRSTQFLTEYQQAFM 1835
>39786
Length = 467
Score = 44.7 bits (104), Expect(2) = 6e-12, Method: Compositional matrix adjust.
Identities = 19/43 (44%), Positives = 31/43 (72%)
Frame = +3
Query: 1 MKIEEVKSTTKTQRIASHSHVKGLGLDESGLAKQAASGLVGQE 43
+K EV+ T+ +RI +HSH++GLGLD+ A+ + G+VGQ+
Sbjct: 144 LKKYEVRDITRIERIGAHSHIRGLGLDDVLEARAVSQGMVGQK 272
Score = 43.9 bits (102), Expect(2) = 6e-12, Method: Compositional matrix adjust.
Identities = 24/68 (35%), Positives = 40/68 (58%), Gaps = 3/68 (4%)
Frame = +1
Query: 42 QENAREACGVIVELIKSKKMAGRAVLLAGPPGT---GKTALALAIAQELGSKVPFCPMVG 98
+++AR A GV+V++++ K R L + K +A+ +AQ LG++ PF M G
Sbjct: 268 KKDARRAAGVVVQMVREGK--NRRTLHSTSRRAEYRKKLPIAVGMAQALGTETPFTSMSG 441
Query: 99 SEVYSTEI 106
SE+YS E+
Sbjct: 442 SEIYSLEM 465
>20270
Length = 542
Score = 40.0 bits (92), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 32/99 (32%), Positives = 52/99 (52%), Gaps = 1/99 (1%)
Frame = -3
Query: 48 ACGVIVELIKSKKMAGRAVLLAGPPGTGKTALALAIAQELGSKVPFCPMVGSEVYSTEIK 107
AC + L + +K R +LL GPPGTGK+ LA A+A E + F + S++ S +
Sbjct: 423 ACQISPSLHREEK-PWRGILLYGPPGTGKSYLAKAVATEANNST-FFSVSSSDLVSKWLG 250
Query: 108 KTEVLMEN-FRRAIGLRIKETKEVYEGEVTELTPCETEN 145
++E L++ F+ A R + ++ EV L +EN
Sbjct: 249 ESEKLVKTLFQLA---RENQPSIIFIDEVDALCGSRSEN 142
>23766
Length = 1463
Score = 39.3 bits (90), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 21/47 (44%), Positives = 29/47 (61%)
Frame = +1
Query: 55 LIKSKKMAGRAVLLAGPPGTGKTALALAIAQELGSKVPFCPMVGSEV 101
L + A + V+L GPPGTGKT LA A+A + + F +VGSE+
Sbjct: 130 LRRDGNQAPKGVILYGPPGTGKTLLAKAVANQ--TSATFLRVVGSEL 264
>07243
Length = 1112
Score = 36.6 bits (83), Expect = 0.020, Method: Compositional matrix adjust.
Identities = 23/58 (39%), Positives = 32/58 (55%), Gaps = 3/58 (5%)
Frame = +1
Query: 64 RAVLLAGPPGTGKTALALAIAQELGSKVPFCPMVGSEVYSTEIKKTEVL---MENFRR 118
+ LL GPPGTGKT LA A+A +L + F +V S + I ++ L M N+ R
Sbjct: 310 KGCLLYGPPGTGKTLLARAVASQLDAN--FLKVVSSAIVDKYIGESARLIREMFNYAR 477
>19129
Length = 1020
Score = 36.6 bits (83), Expect = 0.023, Method: Compositional matrix adjust.
Identities = 19/38 (50%), Positives = 25/38 (65%)
Frame = +1
Query: 64 RAVLLAGPPGTGKTALALAIAQELGSKVPFCPMVGSEV 101
+ VLL GPPGTGKT LA A+A ++ F + GSE+
Sbjct: 592 KGVLLYGPPGTGKTLLARAVAHH--TECTFIRVSGSEL 699
>01642
Length = 1406
Score = 36.6 bits (83), Expect = 0.024, Method: Compositional matrix adjust.
Identities = 19/37 (51%), Positives = 23/37 (62%)
Frame = -1
Query: 64 RAVLLAGPPGTGKTALALAIAQELGSKVPFCPMVGSE 100
R VL+ GPPG GKT LA A+A + F +VGSE
Sbjct: 890 RGVLMYGPPGCGKTMLAKAVAHH--TTAAFIRVVGSE 786
>17843
Length = 772
Score = 36.2 bits (82), Expect = 0.025, Method: Compositional matrix adjust.
Identities = 15/25 (60%), Positives = 18/25 (72%)
Frame = +1
Query: 63 GRAVLLAGPPGTGKTALALAIAQEL 87
R +LL GPPGTGKT L A+A +L
Sbjct: 184 NRVILLHGPPGTGKTTLCKALAHKL 258
>03022
Length = 2255
Score = 34.7 bits (78), Expect = 0.076, Method: Compositional matrix adjust.
Identities = 28/104 (26%), Positives = 49/104 (47%), Gaps = 1/104 (0%)
Frame = +2
Query: 66 VLLAGPPGTGKTALALAIAQELGSKVPFCPMVGSEVYSTEIKKTEV-LMENFRRAIGLRI 124
++L GPPG GKT +A A+A E G + F + G E+ + ++E L E F +A
Sbjct: 1538 IILVGPPGCGKTLVAKAMANEAG--LNFIYIKGPELLDKYVGESERNLREKFDKAQAC-- 1705
Query: 125 KETKEVYEGEVTELTPCETENPMGGYGKTISHVIIGLKTAKGTK 168
++ E+ L N GK++++ ++ L G +
Sbjct: 1706 -APCLIFFDEMDTLCSNRQNNDGSNVGKSVTNQLLALMDGCGER 1834
>19561
Length = 474
Score = 33.9 bits (76), Expect = 0.14, Method: Compositional matrix adjust.
Identities = 23/73 (31%), Positives = 33/73 (45%)
Frame = -1
Query: 51 VIVELIKSKKMAGRAVLLAGPPGTGKTALALAIAQELGSKVPFCPMVGSEVYSTEIKKTE 110
V EL K+ + LL GPPG GKT LA +A+ G V E+ +++ + E
Sbjct: 417 VSSELDDFKRPVQKVALLCGPPGLGKTTLAHIVAKHAGYNV-------VEMNASDDRSVE 259
Query: 111 VLMENFRRAIGLR 123
V A +R
Sbjct: 258 VFSNKIEAATQMR 220
>26408
Length = 463
Score = 33.1 bits (74), Expect = 0.23, Method: Compositional matrix adjust.
Identities = 15/23 (65%), Positives = 17/23 (73%)
Frame = +1
Query: 64 RAVLLAGPPGTGKTALALAIAQE 86
+ VLL GPPGTGKT LA A+A
Sbjct: 367 KGVLLYGPPGTGKTLLARAVAHH 435
>27434
Length = 472
Score = 33.1 bits (74), Expect = 0.26, Method: Compositional matrix adjust.
Identities = 14/38 (36%), Positives = 23/38 (60%)
Frame = +2
Query: 51 VIVELIKSKKMAGRAVLLAGPPGTGKTALALAIAQELG 88
+ V +K+ ++ G + GPPG GKT++ +IA LG
Sbjct: 125 LAVRQMKTTQLKGPILCFVGPPGVGKTSIGRSIATTLG 238
>09184
Length = 1242
Score = 28.9 bits (63), Expect = 4.4, Method: Compositional matrix adjust.
Identities = 20/54 (37%), Positives = 29/54 (53%), Gaps = 2/54 (3%)
Frame = -3
Query: 39 LVGQENAREACGVIVELIKSKKMAGRA--VLLAGPPGTGKTALALAIAQELGSK 90
LVG+E G I++ + S G A + ++G PGTGKTA L I + +K
Sbjct: 454 LVGRETE---VGEIMDFMTSHFDRGSAGSLYISGAPGTGKTAALLHIIDDFRTK 302
>15498
Length = 769
Score = 28.9 bits (63), Expect = 4.6, Method: Compositional matrix adjust.
Identities = 12/28 (42%), Positives = 20/28 (71%)
Frame = -1
Query: 64 RAVLLAGPPGTGKTALALAIAQELGSKV 91
+++LLAGP G+GK L A+ E+G+ +
Sbjct: 184 KSILLAGPRGSGKKMLVHALCNEVGANL 101
>01586
Length = 1867
Score = 28.9 bits (63), Expect = 4.8, Method: Compositional matrix adjust.
Identities = 15/54 (27%), Positives = 26/54 (48%), Gaps = 3/54 (5%)
Frame = +2
Query: 386 ISEEALNHLGEIGTKTTLRYSVQLLTPANLLAKINGKD---SIEKEHVEEISEL 436
I AL G++GTK +RY +N+ ++ G+D ++ H E + L
Sbjct: 437 IQSAALTSDGKVGTKAYMRYYDNPKEHSNMADQLGGQDGGATVSDHHAESVPRL 598
>30094
Length = 341
Score = 28.1 bits (61), Expect = 8.7, Method: Compositional matrix adjust.
Identities = 10/24 (41%), Positives = 18/24 (75%)
Frame = +2
Query: 266 PKKTEITDKLRGEINKVVNKYIDQ 289
P +TE T+ + E+N +V+KY+D+
Sbjct: 11 PAETEYTETINKELNDIVHKYVDK 82
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000324804 | hsapiens_gene_ensembl |
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A
alpha isoform (PP2A, subunit A, PR65-alpha isoform) (PP2A, subunit A,
R1-alpha isoform) (Medium tumor antigen-associated 61 kDa protein).
[Source:Uniprot/SWISSPROT;Acc:P30153]
(589 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
26856 828 0.0
01469 46 3e-05
25614 41 0.001
30928 31 1.2
14913 31 1.5
09672 28 7.5
36681 28 8.1
>26856
Length = 2013
Score = 828 bits (2138), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 400/517 (77%), Positives = 453/517 (87%)
Frame = +1
Query: 73 LGTFTTLVGGPEYVHCLLPPLESLATVEETVVRDKAVESLRAISHEHSPSDLEAHFVPLV 132
LG FT LVGGP L LESLATVEETVVRDKAV+SLR I+ +HS SDLEAHFVPLV
Sbjct: 13 LGIFTPLVGGPRTCTLLTAALESLATVEETVVRDKAVDSLRNIAAQHSXSDLEAHFVPLV 192
Query: 133 KRLAGGDWFTSRTSACGLFSVCYPRVSSAVKAELRQYFRNLCSDDTPMVRRAAASKLGEF 192
KRL+ GDWFTSRTSACGLF+ CY RV+S+VKA+LRQ FRNLCSDDTPMVRRAAA KLGEF
Sbjct: 193 KRLSTGDWFTSRTSACGLFACCYARVASSVKADLRQLFRNLCSDDTPMVRRAAAGKLGEF 372
Query: 193 AKVLELDNVKSEIIPMFSNLASDEQDSVRLLAVEACVNIAQLLPQEDLEALVMPTLRQAA 252
AK +E + +KS++IP+F+ LA DEQDSVRLLAVEACV+IA LLP ED E LVMPTLRQA+
Sbjct: 373 AKEVESEFLKSDLIPLFAMLAQDEQDSVRLLAVEACVSIASLLPSEDTEQLVMPTLRQAS 552
Query: 253 EDKSWRVRYMVADKFTELQKAVGPEITKTDLVPAFQNLMKDCEAEVRAAASHKVKEFCEN 312
EDKSWRVRYMVADKFTELQKAVGPEITK DLVPAFQ+L+KDCEAEVRAA+++KVK+FC+
Sbjct: 553 EDKSWRVRYMVADKFTELQKAVGPEITKNDLVPAFQSLLKDCEAEVRAASANKVKDFCQA 732
Query: 313 LSADCRENVIMSQILPCIKELVSDANQHVKSALASVIMGLSPILGKDNTIEHLLPLFLAQ 372
LS D RE +IM+ ILPC+K+LV+DANQHVKSALASVIMGLSPILGKDNTIEHLLPLFL+Q
Sbjct: 733 LSPDVRETIIMTNILPCVKDLVADANQHVKSALASVIMGLSPILGKDNTIEHLLPLFLSQ 912
Query: 373 LKDECPEVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAG 432
LKDECP+VRLNIISNLDCVNEVIGI+QLSQSLLPAIVELAED KWRVRLAIIEYMPLLAG
Sbjct: 913 LKDECPDVRLNIISNLDCVNEVIGIKQLSQSLLPAIVELAEDTKWRVRLAIIEYMPLLAG 1092
Query: 433 QLGVEFFDEKLNSLCMAWLVDHVYAIREAATSNLKKLVEKFGKEWAHATIIPKVLAMSGD 492
QLGV+FFDEKLNSLCM WLVDHV+AIREAAT NLKKLVEKFG EWA T+IPKV +MS D
Sbjct: 1093QLGVQFFDEKLNSLCMTWLVDHVFAIREAATLNLKKLVEKFGPEWAQETVIPKVTSMSKD 1272
Query: 493 PNYLHRMTTLFCINVLSEVCGQDITTKHMLPTVLRMAGDPVANVRFNVAKSLQKIGPILD 552
NYLHRMT LF IN+L+E GQ++T+K +LPT +A D V NVRFN AK+LQKI P+LD
Sbjct: 1273SNYLHRMTCLFSINLLAETMGQELTSKLLLPTRF-LARDTVPNVRFNAAKTLQKIAPLLD 1449
Query: 553 NSTLQSEVKPILEKLTQDQDVDVKYFAQEALTVLSLA 589
ST+QS+VKPILE L D D+DV++FA +AL V+ +
Sbjct: 1450QSTVQSQVKPILETLKSDSDIDVQFFAADALDVIGVG 1560
Score = 65.1 bits (157), Expect = 7e-11, Method: Compositional matrix adjust.
Identities = 92/402 (22%), Positives = 159/402 (39%), Gaps = 48/402 (11%)
Frame = +1
Query: 68 ALAEQLGTFTTLVGGPEYVHCLLPPLESLATVEETVVRDKAVESLRAISHEHSPSDLEAH 127
A A +LG F V L+P LA E+ VR AVE+ +I+ D E
Sbjct: 346 AAAGKLGEFAKEVESEFLKSDLIPLFAMLAQDEQDSVRLLAVEACVSIASLLPSEDTEQL 525
Query: 128 FVPLVK----------RLAGGDWFTSRTSACG--------------LFSVCYPRVSSAVK 163
+P ++ R D FT A G L C V +A
Sbjct: 526 VMPTLRQASEDKSWRVRYMVADKFTELQKAVGPEITKNDLVPAFQSLLKDCEAEVRAASA 705
Query: 164 AELRQY--------------------FRNLCSDDTPMVRRAAASKLGEFAKVLELDNVKS 203
+++ + ++L +D V+ A AS + + +L DN
Sbjct: 706 NKVKDFCQALSPDVRETIIMTNILPCVKDLVADANQHVKSALASVIMGLSPILGKDNTIE 885
Query: 204 EIIPMFSNLASDEQDSVRLLAVEA--CVNIAQLLPQEDLEALVMPTLRQAAEDKSWRVRY 261
++P+F + DE VRL + CVN +++ + L ++P + + AED WRVR
Sbjct: 886 HLLPLFLSQLKDECPDVRLNIISNLDCVN--EVIGIKQLSQSLLPAIVELAEDTKWRVRL 1059
Query: 262 MVADKFTELQKAVGPEITKTDLVPAFQNLMKDCEAEVRAAASHKVKEFCENLSADCRENV 321
+ + L +G + L + D +R AA+ +K+ E + +
Sbjct: 1060AIIEYMPLLAGQLGVQFFDEKLNSLCMTWLVDHVFAIREAATLNLKKLVEKFGPEWAQET 1239
Query: 322 IMSQILPCIKELVSDANQ-HVKSALASVIMGLSPILGKDNTIEHLLPL-FLAQLKDECPE 379
++P + + D+N H + L S+ + L+ +G++ T + LLP FLA +D P
Sbjct: 1240----VIPKVTSMSKDSNYLHRMTCLFSINL-LAETMGQELTSKLLLPTRFLA--RDTVPN 1398
Query: 380 VRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVRL 421
VR N L + ++ + + P + L D+ V+
Sbjct: 1399VRFNAAKTLQKIAPLLDQSTVQSQVKPILETLKSDSDIDVQF 1524
Score = 52.0 bits (123), Expect = 7e-07, Method: Compositional matrix adjust.
Identities = 50/220 (22%), Positives = 94/220 (42%), Gaps = 5/220 (2%)
Frame = +1
Query: 13 IAVLIDELRNEDVQLRLNSIKKLSTIALALGVERTRSELLPFLTDTIYDED-EVLLALAE 71
+ + + +L++E +RLN I L + +G+++ LLP + + D V LA+ E
Sbjct: 892 LPLFLSQLKDECPDVRLNIISNLDCVNEVIGIKQLSQSLLPAIVELAEDTKWRVRLAIIE 1071
Query: 72 QLGTFTTLVGGPEYVHCLLPPLESLATV----EETVVRDKAVESLRAISHEHSPSDLEAH 127
+ L+ G V L SL +R+ A +L+ + + P +
Sbjct: 1072 ----YMPLLAGQLGVQFFDEKLNSLCMTWLVDHVFAIREAATLNLKKLVEKFGPEWAQET 1239
Query: 128 FVPLVKRLAGGDWFTSRTSACGLFSVCYPRVSSAVKAELRQYFRNLCSDDTPMVRRAAAS 187
+P V ++ + R + ++ + + ++L R L D P VR AA
Sbjct: 1240 VIPKVTSMSKDSNYLHRMTCLFSINLLAETMGQELTSKLLLPTRFLARDTVPNVRFNAAK 1419
Query: 188 KLGEFAKVLELDNVKSEIIPMFSNLASDEQDSVRLLAVEA 227
L + A +L+ V+S++ P+ L SD V+ A +A
Sbjct: 1420 TLQKIAPLLDQSTVQSQVKPILETLKSDSDIDVQFFAADA 1539
>01469
Length = 2023
Score = 46.2 bits (108), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 37/138 (26%), Positives = 61/138 (44%), Gaps = 3/138 (2%)
Frame = +1
Query: 247 TLRQAAEDKSWRVRYMVADKFTELQKAVGPEITKTDLVPAFQNLMKDCEAEVRAAASHKV 306
TL QA + W+VR +A E+ G IT DL+P F +KD + EVR +
Sbjct: 454 TLAQAMQ---WKVRRTLAFSIHEMALIEGEAITHNDLLPVFDGFIKDLD-EVRIGVLKHL 621
Query: 307 KEFCENLSADCRENVIMSQILPCIKELVSDANQ---HVKSALASVIMGLSPILGKDNTIE 363
+F L + R+ Q L + + + N + L+ ++ L + + +
Sbjct: 622 ADFLRLLRPNVRQ-----QYLAKVSDFMKTDNHRNWRFRKELSEQLIYLCELFDPRSIVR 786
Query: 364 HLLPLFLAQLKDECPEVR 381
H+ PL +A D+ EVR
Sbjct: 787 HICPLAVALCMDKVAEVR 840
Score = 38.1 bits (87), Expect = 0.011, Method: Compositional matrix adjust.
Identities = 67/276 (24%), Positives = 121/276 (43%), Gaps = 23/276 (8%)
Frame = +1
Query: 329 CIKELVSDANQ----HVKSALASVIMGLSPILGKDNTIEHLLPLFLAQLKDECPEVRLNI 384
CIK L Q V+ LA I ++ I G+ T LLP+F +KD EVR+ +
Sbjct: 433 CIKHLYETLAQAMQWKVRRTLAFSIHEMALIEGEAITHNDLLPVFDGFIKD-LDEVRIGV 609
Query: 385 ISNLDCVNEVI--GIRQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAGQLGVEFFDEK 442
+ +L ++ +RQ + + ++ WR R + E + L E FD +
Sbjct: 610 LKHLADFLRLLRPNVRQQYLAKVSDFMKTDNHRNWRFRKELSEQLIYLC-----ELFDPR 774
Query: 443 -----LNSLCMAWLVDHVYAIREAATSNLKKLVEKFGKEWAHATIIPKVLAMSGDPNYLH 497
+ L +A +D V +R A + L V + E ++ + + D L+
Sbjct: 775 SIVRHICPLAVALCMDKVAEVR-AVSFGLMSAVLRRVHEEGEDKLLQVICSDLSDQFALN 951
Query: 498 ------RMTTLFCINVLSE-VCGQDITTKHMLPTVLRMAGDPVANVRFNVAKSL-QKIGP 549
++ C+ VL++ + + +LP +L + D + NVR +AK L Q++ P
Sbjct: 952 IKWLGRQIYCQMCLVVLADNAVPPPVFAELLLPGLLALGTDAIPNVRLTLAKVLAQRVAP 1131
Query: 550 ILDNSTLQSEVK----PILEKLTQDQDVDVKYFAQE 581
+ ++ Q+ L+ L D+D DV+YF+ +
Sbjct: 1132LDYFTSSQNPCHEALLTTLQALKTDKDQDVRYFSSQ 1239
>25614
Length = 433
Score = 41.2 bits (95), Expect = 0.001, Method: Composition-based stats.
Identities = 35/116 (30%), Positives = 48/116 (41%)
Frame = -2
Query: 365 LLPLFLAQLKDECPEVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVRLAII 424
LLP F L D VR +N V V+G + + LLP + L ED W VR A
Sbjct: 408 LLPRFSQMLTDPLFHVRKVCAANFGEVCSVVGKQSSEELLLPKLNSLCEDGVWGVRKACA 229
Query: 425 EYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATSNLKKLVEKFGKEWAHA 480
E ++ +E L L + L D +R +A +L + F AHA
Sbjct: 228 ECFMAISCACSLETRRGYLARLFVHLLADQSRWVRMSAFQHLGPFISTF----AHA 73
Score = 30.8 bits (68), Expect = 1.5, Method: Composition-based stats.
Identities = 19/101 (18%), Positives = 44/101 (43%)
Frame = -2
Query: 451 LVDHVYAIREAATSNLKKLVEKFGKEWAHATIIPKVLAMSGDPNYLHRMTTLFCINVLSE 510
L D ++ +R+ +N ++ GK+ + ++PK+ ++ D + R C +S
Sbjct: 384 LTDPLFHVRKVCAANFGEVCSVVGKQSSEELLLPKLNSLCEDGVWGVRKACAECFMAISC 205
Query: 511 VCGQDITTKHMLPTVLRMAGDPVANVRFNVAKSLQKIGPIL 551
C + ++ + + D VR + + Q +GP +
Sbjct: 204 ACSLETRRGYLARLFVHLLADQSRWVRMS---AFQHLGPFI 91
>30928
Length = 343
Score = 31.2 bits (69), Expect = 1.2, Method: Composition-based stats.
Identities = 18/57 (31%), Positives = 28/57 (49%)
Frame = +2
Query: 205 IIPMFSNLASDEQDSVRLLAVEACVNIAQLLPQEDLEALVMPTLRQAAEDKSWRVRY 261
I+P +DE + VR A+ A I +E L++P L + D +WR+RY
Sbjct: 89 ILPSILQALADESEFVRDTALRAGQRIISQYADTAIE-LLLPELERGLFDDNWRIRY 256
>14913
Length = 1174
Score = 30.8 bits (68), Expect = 1.5, Method: Compositional matrix adjust.
Identities = 24/88 (27%), Positives = 46/88 (52%), Gaps = 6/88 (6%)
Frame = -3
Query: 128 FVPLVKRLAGGDWFTSRTSACGLFSVCYPRVSSAVKAELRQ-YFRNLC---SDDTPMVRR 183
+P+V++ D R ++ +V + V ++L + +++C +D PMVR
Sbjct: 272 LMPMVEKCMTSDKGKERRASYLAMAVVVEGCADYVMSKLMKVMLQSVCQGLNDSEPMVRN 93
Query: 184 AAASKLGEFAKVLELDNVK--SEIIPMF 209
AA LG+F++ L+ D K SE++P+
Sbjct: 92 AALFALGQFSEHLQPDITKFASELLPLL 9
>09672
Length = 1963
Score = 28.5 bits (62), Expect = 7.5, Method: Compositional matrix adjust.
Identities = 22/78 (28%), Positives = 36/78 (46%), Gaps = 6/78 (7%)
Frame = -2
Query: 310 CENLSADCRENVIMSQILPCIKELVSDANQHVKSALASVIMGLSPIL-GKDN-----TIE 363
C L A C E+ ++ +LP +KE + A+ + A +M IL G D+ +E
Sbjct: 1959 CLMLMATCCEDDVVPHVLPFVKENIRHADWRYRDA---AVMAFGSILEGPDSEKLKPIVE 1789
Query: 364 HLLPLFLAQLKDECPEVR 381
+P+ + L D VR
Sbjct: 1788 QAMPMLIELLTDPSVVVR 1735
>36681
Length = 1210
Score = 28.5 bits (62), Expect = 8.1, Method: Compositional matrix adjust.
Identities = 26/67 (38%), Positives = 34/67 (50%), Gaps = 7/67 (10%)
Frame = -3
Query: 78 TLVGGP-----EYVHCLLPPLESLATVEETVVRDKAVESLRAISHEHS--PSDLEAHFVP 130
+LV GP YV LP + L V+ + VESL ++ H HS P+ +E HF
Sbjct: 227 SLVPGPFYHDARYVGVRLP-FQHLGIDMADHVQVERVESLGSVEHNHSFVPNCIEQHF-- 57
Query: 131 LVKRLAG 137
V RLAG
Sbjct: 56 -VCRLAG 39
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000326804 | hsapiens_gene_ensembl | Cullin-1
(CUL-1). [Source:Uniprot/SWISSPROT;Acc:Q13616]
(776 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
02265 631 0.0
02365 242 1e-84
33018 44 3e-04
01055 30 3.7
03172 30 4.9
>02265
Length = 1094
Score = 631 bits (1627), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 296/356 (83%), Positives = 327/356 (91%)
Frame = +3
Query: 79 GGAQFVGLELYKRLKEFLKNYLTNLLKDGEDLMDESVLKFYTQQWEDYRFSSKVLNGICA 138
GGAQFVG ELYKR+K+FLKNYL NLLKDG+DL+DE VL+FYT+QWEDY+FSSKVL+GICA
Sbjct: 27 GGAQFVGHELYKRMKDFLKNYLVNLLKDGQDLLDEQVLQFYTRQWEDYQFSSKVLDGICA 206
Query: 139 YLNRHWVRRECDEGRKGIYEIYSLALVTWRDCLFRPLNKQVTNAVLKLIEKERNGETINT 198
YLNRHWVRRECDEG KGIY IYSLAL+TWR+CLF+PLNKQVTNAVLKLIEKERNGETINT
Sbjct: 207 YLNRHWVRRECDEGTKGIYYIYSLALITWRECLFKPLNKQVTNAVLKLIEKERNGETINT 386
Query: 199 RLISGVVQSYVELGLNEDDAFAKGPTLTVYKESFESQFLADTERFYTRESTEFLQQNPVT 258
RL+SGV+ YVELGLNE+D AKGPTL VYK+ FE+ FL DTER+YTRESTEFL+QNPVT
Sbjct: 387 RLVSGVINCYVELGLNEEDPSAKGPTLGVYKDHFETPFLDDTERYYTRESTEFLRQNPVT 566
Query: 259 EYMKKAEARLLEEQRRVQVYLHESTQDELARKCEQVLIEKHLEIFHTEFQNLLDADKNED 318
EYMKKAE RL EEQ+RVQ YLHEST D LA+ CE+VLIEKHLEIFH EFQNLLD DKNED
Sbjct: 567 EYMKKAEMRLKEEQKRVQTYLHESTHDSLAKVCERVLIEKHLEIFHFEFQNLLDTDKNED 746
Query: 319 LGRMYNLVSRIQDGLGELKKLLETHIHNQGLAAIEKCGEAALNDPKMYVQTVLDVHKKYN 378
LGRMY LVSRI DGLGELK LLE+HIH QGLAAIE+CG+AALNDPK+YVQT+LDVHKKYN
Sbjct: 747 LGRMYMLVSRILDGLGELKTLLESHIHTQGLAAIERCGDAALNDPKVYVQTILDVHKKYN 926
Query: 379 ALVMSAFNNDAGFVAALDKACGRFINNNAVTKMAQSSSKSPELLARYCDSLLKKSS 434
ALV++AF NDAGFVAALDKACGRFINNN+VTKM ++SKSPELLARYCD LLKKSS
Sbjct: 927 ALVLTAFVNDAGFVAALDKACGRFINNNSVTKMVNNTSKSPELLARYCDLLLKKSS 1094
>02365
Length = 1804
Score = 242 bits (617), Expect(2) = 1e-84, Method: Compositional matrix adjust.
Identities = 145/426 (34%), Positives = 232/426 (54%), Gaps = 26/426 (6%)
Frame = +1
Query: 377 YNALVMSAFNNDAGFVAALDKACGRFINNNAVTKMAQSSSKSPELLARYCDSLLKKSSKN 436
+N + +FN D F + FIN N KSPE L+ + D LKK K
Sbjct: 529 FNHFLHESFNEDKQFKQMISSGFEHFINLNP---------KSPEYLSLFIDDKLKKGVKG 681
Query: 437 PEEAELEDTLNQVMVVFKYIEDKDVFQKFYAKMLAKRLVHQNSASDDAEASMISKLKQAC 496
E E+E L++ MV+F+Y+++KDVF+++Y + LA+RL+ S SDD+E +MISKLK C
Sbjct: 682 MSEQEIEVVLDKSMVLFRYLQEKDVFERYYKQHLARRLLLNKSGSDDSEKNMISKLKTEC 861
Query: 497 GFEYTSKLQRMFQDIGVSKDLNEQFKKHLTNSEPLDL---DFSIQVLSSGSWPFQQSCTF 553
G ++TSKL+ MF+D+ VS +N++FK + ++ ++L + +++VL++G WP Q +
Sbjct: 862 GCQFTSKLEGMFKDMTVSSGINDEFKASVQQTQVVNLSGVELTVRVLTTGYWPTQSATPI 1041
Query: 554 ALPSELERSYQRFTAFYASRHSGRKLTWLYQLSKGELVTNCF------------------ 595
+P + +++ F FY ++HSGR+LT L +L + F
Sbjct: 1042NIPVDPRTAFEAFRRFYLAKHSGRQLTLQPHLGSADLHASFFGQKKDDSADSAAASSSKP 1221
Query: 596 --KNRYTLQASTFQMAILLQYNTEDAYTVQQL-TDSTQIKMDILAXXXXXXXXXXXXXXE 652
++ LQ ST+QM ILL +N D +T +++ T++ +++
Sbjct: 1222AGPRKHILQVSTYQMCILLLFNNRDKWTFEEIKTETDMPDRELIRALQSLAVGKLAQRVL 1401
Query: 653 DENANVDEVELKPDTLIKLYLGYKNKKLRVNINVPM--KTEQKQEQETTHKNIEEDRKLL 710
+ E+E PD + + + +K +RV I + K E + E++ T ++EDRK
Sbjct: 1402HKEPKTKEIE--PDHIFTVNDQFTSKLIRVKIQMVASNKGEAEPERKETRNKVDEDRKHE 1575
Query: 711 IQAAIVRIMKMRKVLKHQQLLGEVLTQLSSRFKPRVPVIKKCIDILIEKEYLERVDGEKD 770
I+AAIVRIMK RK L+H L+ EV L RF P VIKK I+ LIE+EYL R ++
Sbjct: 1576IEAAIVRIMKARKKLQHNVLVTEVTEMLKPRFLPSPVVIKKRIEGLIEREYLARSQEDRK 1755
Query: 771 TYSYLA 776
Y+Y+A
Sbjct: 1756IYTYVA 1773
Score = 90.9 bits (224), Expect(2) = 1e-84, Method: Compositional matrix adjust.
Identities = 56/156 (35%), Positives = 90/156 (57%), Gaps = 4/156 (2%)
Frame = +3
Query: 226 TVYKESFESQFLADTERFYTRESTEFLQQNPVTEYMKKAEARLLEEQRRVQVYLHESTQD 285
TVY+E FE FL + FY ES +FL +N + Y+KK EAR+ EE R YL +ST+D
Sbjct: 66 TVYEEDFEKPFLEQSAEFYRLESQKFLAENSASVYIKKVEARINEEAERATHYLDKSTED 245
Query: 286 ELARKCEQVLIEKHL----EIFHTEFQNLLDADKNEDLGRMYNLVSRIQDGLGELKKLLE 341
+ R E+ LI KH+ E+ ++ ++L+ +K +DL MY L R+ GL + + +
Sbjct: 246 PVVRVLEEELISKHMKTIVEMENSGVVHMLENNKTDDLACMYKLFFRVVYGLRTMCQCIS 425
Query: 342 THIHNQGLAAIEKCGEAALNDPKMYVQTVLDVHKKY 377
+ QG A + + E + N YVQ++LD++ ++
Sbjct: 426 QFLREQGRALVIEEAEESKN-AITYVQSLLDLNDRF 530
>33018
Length = 814
Score = 43.9 bits (102), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 25/100 (25%), Positives = 45/100 (45%)
Frame = -3
Query: 532 DLDFSIQVLSSGSWPFQQSCTFALPSELERSYQRFTAFYASRHSGRKLTWLYQLSKGELV 591
DLD S +LS+ WP + LP++L+ S +T Y + R L W L +
Sbjct: 704 DLDISAIILSAQFWPSFREEKITLPAQLQSSLDSYTQQYETLKGNRTLVWKPHLGVMNIE 525
Query: 592 TNCFKNRYTLQASTFQMAILLQYNTEDAYTVQQLTDSTQI 631
S Q A+++Q+ ++ +TV+ L + ++
Sbjct: 524 LELKDQTLNFSVSPVQAALIMQFQDQNRWTVEDLGQALEM 405
>01055
Length = 522
Score = 30.0 bits (66), Expect = 3.7, Method: Composition-based stats.
Identities = 13/40 (32%), Positives = 22/40 (55%)
Frame = -2
Query: 106 DGEDLMDESVLKFYTQQWEDYRFSSKVLNGICAYLNRHWV 145
+G + +S + FY +W +Y + + N IC YLN +V
Sbjct: 521 NGLLMSQDSRMFFYILEWSNYSAPNCLCNCICPYLNEKFV 402
>03172
Length = 2411
Score = 29.6 bits (65), Expect = 4.9, Method: Compositional matrix adjust.
Identities = 13/39 (33%), Positives = 21/39 (53%)
Frame = +3
Query: 690 TEQKQEQETTHKNIEEDRKLLIQAAIVRIMKMRKVLKHQ 728
T Q + +T H+ EDR + IQA + + + R L+ Q
Sbjct: 1422 TRQSEVDKTVHREPREDRLITIQATLANVGQSRSCLQGQ 1538
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000335153 | hsapiens_gene_ensembl | Heat shock
protein HSP 90-alpha (HSP 86) (Renal carcinoma antigen NY- REN-38).
[Source:Uniprot/SWISSPROT;Acc:P07900]
(854 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
01628 684 0.0
15623 322 e-100
11278 222 5e-58
27487 155 8e-38
25874 80 3e-15
>01628
Length = 2109
Score = 684 bits (1764), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 332/444 (74%), Positives = 381/444 (85%), Gaps = 1/444 (0%)
Frame = -3
Query: 412 LNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPF 471
LNKTKP+WTRNPDDIT EEY EFYKSLTNDWEDHLAVKHFSVEGQLEFRALLF+P+RAPF
Sbjct: 1951 LNKTKPLWTRNPDDITAEEYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPKRAPF 1772
Query: 472 DLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKIL 531
D+FEN+KKKNNIKLYVRRVFIMDNCE++IPEYLNF++GVVDSEDLPLNISREMLQQSKIL
Sbjct: 1771 DMFENKKKKNNIKLYVRRVFIMDNCEDIIPEYLNFVKGVVDSEDLPLNISREMLQQSKIL 1592
Query: 532 KVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSA 591
KVIRKNLVKKC+EL +LAEDK+NY KFYEQF+KN+KLGIHEDS NRKK+S+ LRY++S
Sbjct: 1591 KVIRKNLVKKCMELIDDLAEDKDNYNKFYEQFAKNLKLGIHEDSTNRKKISDFLRYHSSQ 1412
Query: 592 SGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYC 651
S DEMV+ K+Y +RMK+NQK IYYITGET++ V NSAFVER++K G EV+YM++PIDEYC
Sbjct: 1411 SADEMVTFKEYVSRMKDNQKDIYYITGETREAVQNSAFVERVKKRGFEVLYMVDPIDEYC 1232
Query: 652 VQQLKEFEGKTLVSVTXXXXXXXXXXXXXXXXXXXXXXXXNLCKIMKDILEKKVEKVVVS 711
VQQLKE++GK LV VT LCK MK+IL+KKVEKV VS
Sbjct: 1231 VQQLKEYDGKNLVCVTKEGLELPEDEAEKKKFEEAKAEFEGLCKAMKEILDKKVEKVTVS 1052
Query: 712 NRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQK 771
RLV+SPCCIVTS YGW+ANMERIMKAQALRD STMGYMAAKKH EINPDH I++TL+ K
Sbjct: 1051 QRLVSSPCCIVTSQYGWSANMERIMKAQALRDTSTMGYMAAKKHFEINPDHPIVKTLKVK 872
Query: 772 AEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTS 831
+ADKNDKSVKDL +LL+ETALLSSGF+LEDP +HANRI+RM+KLGLGIDEDD T + +
Sbjct: 871 CDADKNDKSVKDLCMLLFETALLSSGFTLEDPTSHANRIHRMVKLGLGIDEDDSTP-EAA 695
Query: 832 AAVTEEMPPLEGD-DDTSRMEEVD 854
A ++MPPLEGD DD SRMEEVD
Sbjct: 694 EAPADDMPPLEGDEDDASRMEEVD 623
>15623
Length = 2811
Score = 322 bits (826), Expect(2) = e-100, Method: Compositional matrix adjust.
Identities = 151/186 (81%), Positives = 171/186 (91%)
Frame = -1
Query: 163 KEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTK 222
+EIFLRELISNSSDALDKIRYESLTDPSKLD+GK+LHI ++P+K+ +TLTI D+GIGMTK
Sbjct: 585 QEIFLRELISNSSDALDKIRYESLTDPSKLDAGKDLHIRIVPDKERKTLTIEDSGIGMTK 406
Query: 223 ADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQY 282
ADL+NNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVA++V V +K+NDDEQY
Sbjct: 405 ADLVNNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVADRVVVESKNNDDEQY 226
Query: 283 AWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITL 342
WESSAGGSFT+ TG PMGRGT++ L +KEDQ EYLEERRIKE++KKHSQFIGYPI L
Sbjct: 225 TWESSAGGSFTIAAPTGTPMGRGTRITLFMKEDQQEYLEERRIKEVIKKHSQFIGYPIKL 46
Query: 343 FVEKER 348
VEKER
Sbjct: 45 LVEKER 28
Score = 63.9 bits (154), Expect(2) = e-100, Method: Compositional matrix adjust.
Identities = 35/45 (77%), Positives = 35/45 (77%)
Frame = -2
Query: 119 LRLLMPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNK 163
L MPEET MEE EVETFAFQAEIAQLMSLIINTFYSNK
Sbjct: 704 LHTKMPEETA----QMEETEVETFAFQAEIAQLMSLIINTFYSNK 582
>11278
Length = 988
Score = 222 bits (566), Expect = 5e-58, Method: Compositional matrix adjust.
Identities = 114/214 (53%), Positives = 150/214 (70%), Gaps = 4/214 (1%)
Frame = +1
Query: 137 EEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGK 196
E+ E FAFQAE+ ++M LIIN+ Y NKEIFLRELISN+SDALDKIR+ SLT+ L +
Sbjct: 250 EKSEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRFMSLTNKDVLHATD 429
Query: 197 ELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADI---SMI 253
EL I + + ++ L + DTGIGMT DL+ NLGTIAKSGT F+ + + +I
Sbjct: 430 ELSIKIKADTENHVLHVTDTGIGMTYNDLVKNLGTIAKSGTSDFLAKMGEASPTELNDLI 609
Query: 254 GQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTD-TGEPMGRGTKVILHL 312
GQFGVGFYS++LVA++V V +KHNDDEQY WES A SF+V D G +GRGT + LHL
Sbjct: 610 GQFGVGFYSSFLVADRVVVTSKHNDDEQYVWESDA-ESFSVAKDPRGNTLGRGTTISLHL 786
Query: 313 KEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEK 346
KE+ ++LE + +VKK+SQFI + I ++ K
Sbjct: 787 KEEAHDFLEAGTLTSLVKKYSQFINFNIYMWSSK 888
>27487
Length = 377
Score = 155 bits (391), Expect = 8e-38, Method: Compositional matrix adjust.
Identities = 79/124 (63%), Positives = 106/124 (85%)
Frame = -3
Query: 525 LQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSEL 584
LQQ+KILKVI+KN+VKKCLE+F E+AE+ ++YKKFYEQFSKN+KLGIHED+ NR KL +L
Sbjct: 372 LQQNKILKVIKKNIVKKCLEMFAEIAENNDDYKKFYEQFSKNLKLGIHEDTTNRTKLVDL 193
Query: 585 LRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMI 644
+R++TS SG++ +SLK+Y RMKE QK I+YITGE++ V S F+E+LRK G EV+Y++
Sbjct: 192 MRFHTSKSGEDQISLKEYIARMKEGQKDIFYITGESRAAVQASPFIEQLRKKGYEVLYLV 13
Query: 645 EPID 648
+PID
Sbjct: 12 DPID 1
>25874
Length = 476
Score = 80.1 bits (196), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 39/91 (42%), Positives = 57/91 (62%)
Frame = +1
Query: 252 MIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILH 311
+IGQFGVGFYS ++V ++V V TK + A + S+ GS E + RGTK+++H
Sbjct: 1 LIGQFGVGFYSTFMVGDRVDVFTKSHQPGSPALKWSSDGSGAYEVSEAEGVQRGTKIVVH 180
Query: 312 LKEDQTEYLEERRIKEIVKKHSQFIGYPITL 342
LK D ++ +E I +VKK+S F+G PI L
Sbjct: 181 LKGDSYDFAKEEIITGVVKKYSNFVGVPIYL 273
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000372035 | hsapiens_gene_ensembl |
Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Large tumor
suppressor homolog 2) (Serine/threonine-protein kinase kpm) (Kinase
phosphorylated during mitosis protein) (Warts-like kinase).
[Source:Uniprot/SWISSPROT;Acc:Q9NRM7]
(1088 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
03240 635 0.0
30755 112 6e-25
31885 99 8e-21
18484 99 1e-20
12721 97 4e-20
27405 96 6e-20
14420 93 7e-19
00300 91 3e-18
00486 87 5e-17
09606 81 3e-15
13592 80 6e-15
18921 79 1e-14
26560 77 4e-14
26156 64 7e-14
18663 76 8e-14
15910 71 2e-12
17932 57 1e-11
17975 67 5e-11
21079 63 5e-10
13212 63 5e-10
01707 62 1e-09
01060 59 1e-08
33586 47 1e-08
01756 57 3e-08
01392 57 4e-08
16708 55 1e-07
21433 55 2e-07
02638 55 2e-07
19094 55 2e-07
13066 54 3e-07
01966 54 3e-07
06405 54 4e-07
12786 53 6e-07
26711 53 8e-07
25019 52 1e-06
14126 52 1e-06
27546 52 2e-06
03508 51 2e-06
11185 51 2e-06
29581 51 2e-06
17722 50 3e-06
18401 49 1e-05
01718 47 3e-05
37602 46 7e-05
32957 45 1e-04
04591 45 1e-04
29590 45 2e-04
17516 44 5e-04
14477 44 5e-04
32359 35 5e-04
04138 43 5e-04
28157 43 7e-04
28638 43 7e-04
00715 43 7e-04
18481 42 0.002
04852 42 0.002
19301 42 0.002
19761 41 0.003
20152 41 0.003
01106 41 0.003
21808 40 0.006
00638 39 0.011
14116 38 0.021
31489 38 0.023
20640 37 0.034
07940 37 0.038
00392 37 0.047
12672 37 0.062
23319 36 0.095
11404 36 0.10
09007 35 0.12
17591 27 0.13
21800 35 0.14
26009 35 0.14
11780 35 0.16
17300 34 0.25
29360 34 0.39
18996 34 0.39
13078 33 0.47
22153 33 0.60
07836 32 1.1
37063 32 1.5
26058 32 1.6
31120 32 1.8
17637 31 2.7
13305 31 3.3
22098 30 4.4
02124 30 7.1
>03240
Length = 1683
Score = 635 bits (1637), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 327/483 (67%), Positives = 378/483 (78%), Gaps = 5/483 (1%)
Frame = -3
Query: 576 SPVPVRK---NSRDEEKRESRIKSYSPYAFKFFMEQHVENVIKTYQQKVNRRLQLEQEMA 632
SP+P RK RD+ +R++++++YSP AFKF+MEQHVENV+K +QQ++ RR QLE EMA
Sbjct: 1570 SPMPQRKPEARERDKLRRDTKVRNYSPQAFKFYMEQHVENVLKIHQQRLRRRTQLENEMA 1391
Query: 633 KAGLCEAEQEQMRKILYQKESNYNRLKRAKMDKSMFVKIKTLGIGAFGEVCLACKVDTHA 692
K L E QMR++L+QKESNY RLKRAKMDK MF KIKTLG+GAFGEV L K DT
Sbjct: 1390 KVKLSEEAARQMRRMLHQKESNYIRLKRAKMDKCMFEKIKTLGVGAFGEVSLCRKNDTGM 1211
Query: 693 LYAMKTLRKKDVLNRNQVAHVKAERDILAEADNEWVVKLYYSFQDKDSLYFVMDYIPGGD 752
LYAMKTLRK DVL RNQVAHVKAERDILAEADNEWVVKLYYSFQD + LYFVMDY+PGGD
Sbjct: 1210 LYAMKTLRKSDVLKRNQVAHVKAERDILAEADNEWVVKLYYSFQDHNYLYFVMDYVPGGD 1031
Query: 753 MMSLLIRMEVFPEHLARFYIAELTLAIESVHKMGFIHRDIKPDNILIDLDGHIKLTDFGL 812
+M LLIRME+ E LARFY+AEL AIESVH+MGFIHRDIKPDNILID +GHIKLTDFGL
Sbjct: 1030 LMGLLIRMEILDEPLARFYVAELVQAIESVHRMGFIHRDIKPDNILIDRNGHIKLTDFGL 851
Query: 813 CTGFRWTHNSKYYQK-GSHVRQDSMEPSDLWDDVSNCRCGDRLKTLEQRARKQHQRCLAH 871
CTGFRWTHNSKYYQ+ G+H RQDSME D+ C+C + LK LE+R RK+ QRCLAH
Sbjct: 850 CTGFRWTHNSKYYQRDGTHARQDSMEVKCQLDE--QCQC-EILKPLERR-RKREQRCLAH 683
Query: 872 SLVGTPNYIAPEVLLR-KGYTQLCDWWSVGVILFEMLVGQPPFLAPTPTETQLKVINWEN 930
SLVGTPNYIAPEVL R GYT +CDWWSVGVILFEMLVG PPF A TP ETQ KVINW++
Sbjct: 682 SLVGTPNYIAPEVLSRLGGYTSVCDWWSVGVILFEMLVGHPPFYANTPAETQYKVINWKD 503
Query: 931 TLHIPAQVKLSPEARDLITKLCCSADHRLGRNGADDLKAHPFFSAIDFSSDIRKQPAPYV 990
L IP + LS A+DLI +LCC +D RLG NGA ++K H FF+ ++F + +RKQ PYV
Sbjct: 502 MLKIPRESNLSQPAKDLILRLCCGSDDRLGLNGAGEIKTHMFFAGVNFET-LRKQQPPYV 326
Query: 991 PTISHPMDTSNFDPVDEESPWNDASEGSTKAWDTLTSPNNKHPEHAFYEFTFRRFFDDNG 1050
P I + DTSNFDPVD + N SE + K N KHPEHAF+EFTFRRFFDD G
Sbjct: 325 PNIRYATDTSNFDPVDPDKLRNSDSEENKKVEKL---ENGKHPEHAFFEFTFRRFFDDGG 155
Query: 1051 YPF 1053
+P
Sbjct: 154 HPM 146
>30755
Length = 1137
Score = 112 bits (281), Expect = 6e-25, Method: Compositional matrix adjust.
Identities = 76/247 (30%), Positives = 119/247 (48%), Gaps = 5/247 (2%)
Frame = +2
Query: 762 VFPEHLARFYIAELTLAIESVHKMGFIHRDIKPDNILIDLDGHIKLTDFGLCTGFRWTHN 821
+F E RFY AE+ A+ +H G I+RD+K +N+L+D DGHIK+ DFGLC
Sbjct: 20 IFTEERTRFYGAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCK------- 178
Query: 822 SKYYQKGSHVRQDSMEPSDLWDDVSNCRCGDRLKTLEQRARKQHQRCLAHSLVGTPNYIA 881
+D++ R + GTP Y+A
Sbjct: 179 ---------------------EDITYGRT-------------------TKTFCGTPEYLA 238
Query: 882 PEVLLRKGYTQLCDWWSVGVILFEMLVGQPPFLAPTPTETQLKVINWENTLHIPAQVKLS 941
PEVL Y + DWW GV+++EM+ G+ PF + +I E+ + P + +
Sbjct: 239 PEVLDDNDYGRAVDWWGTGVVMYEMICGRLPFYN-RDHDVLFTLILVED-VKFPRNI--T 406
Query: 942 PEARDLITKLCCSA-DHRLGRNGADDLK---AHPFFSAIDFSSDIRKQPA-PYVPTISHP 996
EA+ L++ L +RLG G DD+K AHPFF++I+++ ++K+ P+ P ++
Sbjct: 407 DEAKSLLSGLLAKDPRNRLG-GGQDDVKEIQAHPFFASINWTDLVQKKITPPFKPQVTSD 583
Query: 997 MDTSNFD 1003
DT FD
Sbjct: 584 TDTRYFD 604
>31885
Length = 529
Score = 99.0 bits (245), Expect = 8e-21, Method: Compositional matrix adjust.
Identities = 65/207 (31%), Positives = 96/207 (46%), Gaps = 5/207 (2%)
Frame = -2
Query: 718 DILAEADNEWVVKLYYSFQDKDSLYFVMDYIPGGDMMSLLIRMEVFPEHLARFYIAELTL 777
D+L D+ ++V L+Y+FQD++ L+ V+D GGD+ + + F E +FY+ +L L
Sbjct: 516 DMLTRLDHPFLVNLWYAFQDEEDLFMVVDLFLGGDLRYHMQQEVSFREDCVKFYLCQLAL 337
Query: 778 AIESVHKMGFIHRDIKPDNILIDLDGHIKLTDFGLCTGFRWTHNSKYYQKGSHVRQDSME 837
++ + +HRDIKPDNIL+D GH +TDF + T +E
Sbjct: 336 VLDYLRSQKIVHRDIKPDNILLDEQGHCHVTDFNIAT--------------------QLE 217
Query: 838 PSDLWDDVSNCRCGDRLKTLEQRARKQHQRCLAHSLVGTPNYIAPEVL-----LRKGYTQ 892
+ LA S GT Y+APEV R+GY
Sbjct: 216 DDE----------------------------LATSTSGTRPYMAPEVYGVAINERRGYGF 121
Query: 893 LCDWWSVGVILFEMLVGQPPFLAPTPT 919
DWWS+GV LFE+L + PF + T
Sbjct: 120 PVDWWSLGVSLFELLKKRRPFSVHSNT 40
>18484
Length = 635
Score = 98.6 bits (244), Expect = 1e-20, Method: Compositional matrix adjust.
Identities = 53/162 (32%), Positives = 78/162 (48%)
Frame = +1
Query: 752 DMMSLLIRMEVFPEHLARFYIAELTLAIESVHKMGFIHRDIKPDNILIDLDGHIKLTDFG 811
D+M + + F E +A FY AE+ + + +H G I+RD+K DN+++D +GHIK+ DFG
Sbjct: 1 DLMYRIQQEGKFKEPVAAFYAAEIAVGLFFLHDQGIIYRDLKLDNVMLDSEGHIKIADFG 180
Query: 812 LCTGFRWTHNSKYYQKGSHVRQDSMEPSDLWDDVSNCRCGDRLKTLEQRARKQHQRCLAH 871
+C GD
Sbjct: 181 MC--------------------------------KEGMTGD---------------ATTR 219
Query: 872 SLVGTPNYIAPEVLLRKGYTQLCDWWSVGVILFEMLVGQPPF 913
+ GTP+YIAPE++L + Y++ DWW+ GV+LFEML GQPPF
Sbjct: 220 TFCGTPDYIAPEIVLYQPYSKSVDWWAYGVLLFEMLAGQPPF 345
>12721
Length = 821
Score = 97.1 bits (240), Expect = 4e-20, Method: Compositional matrix adjust.
Identities = 72/258 (27%), Positives = 119/258 (46%)
Frame = +1
Query: 668 FVKIKTLGIGAFGEVCLACKVDTHALYAMKTLRKKDVLNRNQVAHVKAERDILAEADNEW 727
F+KI G G+ G VC+A D + ++K D+ + + + E ++ + +
Sbjct: 103 FMKI---GEGSTGIVCIATSRDGRQM----AVKKMDLRKQQRRELLFNEVVVMRDYHHPN 261
Query: 728 VVKLYYSFQDKDSLYFVMDYIPGGDMMSLLIRMEVFPEHLARFYIAELTLAIESVHKMGF 787
+V++Y S+ D L+ VM+++ GG + ++ + +A A L A+ +H G
Sbjct: 262 IVEMYNSYLVNDELWVVMEFMEGGALTDIVTNNRMDEVQIATVCRACLK-ALAFLHANGV 438
Query: 788 IHRDIKPDNILIDLDGHIKLTDFGLCTGFRWTHNSKYYQKGSHVRQDSMEPSDLWDDVSN 847
IHRDIK D+IL+ DG +KL DFG C + V QD
Sbjct: 439 IHRDIKSDSILLSHDGKVKLXDFGFC---------------AQVTQD------------- 534
Query: 848 CRCGDRLKTLEQRARKQHQRCLAHSLVGTPNYIAPEVLLRKGYTQLCDWWSVGVILFEML 907
L++R SLVGTP ++APEV+ R Y D WS+G+++ EM+
Sbjct: 535 ---------LQKRK----------SLVGTPYWMAPEVISRLPYGPEVDIWSLGIMVMEMI 657
Query: 908 VGQPPFLAPTPTETQLKV 925
+PPF P + ++
Sbjct: 658 DAEPPFFNEPPLQAMRRI 711
>27405
Length = 532
Score = 96.3 bits (238), Expect = 6e-20, Method: Compositional matrix adjust.
Identities = 53/143 (37%), Positives = 80/143 (55%), Gaps = 4/143 (2%)
Frame = -3
Query: 678 AFGEVCLACKVDTHALYAMKTLRKKDVLNRNQVAHVKAERDILAEADNE----WVVKLYY 733
FGEV K DT +YAMK L KK + + ER +L+ ++V + Y
Sbjct: 530 GFGEVYGCRKADTGKMYAMKCLDKKRIKMKGGETLALNERIMLSLVSTGEGSPFIVCMTY 351
Query: 734 SFQDKDSLYFVMDYIPGGDMMSLLIRMEVFPEHLARFYIAELTLAIESVHKMGFIHRDIK 793
+FQ + L F++D + GGD+ L + VF E RFY AE+ L +E +H ++RD+K
Sbjct: 350 AFQTPEKLCFILDLMNGGDLHYHLSQHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLK 171
Query: 794 PDNILIDLDGHIKLTDFGLCTGF 816
P NIL+D +GH++++D GL F
Sbjct: 170 PANILLDENGHVRISDLGLACDF 102
>14420
Length = 528
Score = 92.8 bits (229), Expect = 7e-19, Method: Composition-based stats.
Identities = 59/200 (29%), Positives = 92/200 (46%)
Frame = +2
Query: 719 ILAEADNEWVVKLYYSFQDKDSLYFVMDYIPGGDMMSLLIRMEVFPEHLARFYIAELTLA 778
++ E N +V S+ + L+ VM+++ GG + ++ + +A E A
Sbjct: 59 VMRENQNPNIVNYLDSYLVGEELWVVMEFLAGGSLTDVVTETCMDEGQIAAV-CRECLQA 235
Query: 779 IESVHKMGFIHRDIKPDNILIDLDGHIKLTDFGLCTGFRWTHNSKYYQKGSHVRQDSMEP 838
+E +H+ IHRDIK DNIL+ +DG +KLTDFG C
Sbjct: 236 LEFLHENQVIHRDIKSDNILLGMDGSVKLTDFGFCA------------------------ 343
Query: 839 SDLWDDVSNCRCGDRLKTLEQRARKQHQRCLAHSLVGTPNYIAPEVLLRKGYTQLCDWWS 898
Q + +Q +R ++VGTP ++APEV+ RK Y D WS
Sbjct: 344 --------------------QLSPEQSKR---STMVGTPYWMAPEVVTRKQYGPTVDIWS 454
Query: 899 VGVILFEMLVGQPPFLAPTP 918
+GV+ EM+ G+PP+L P
Sbjct: 455 LGVMCIEMIEGEPPYLNENP 514
>00300
Length = 2318
Score = 90.9 bits (224), Expect = 3e-18, Method: Compositional matrix adjust.
Identities = 80/309 (25%), Positives = 134/309 (43%), Gaps = 3/309 (0%)
Frame = -1
Query: 608 QHVENVIKTYQQKVNRRLQLEQEMAKAGLCEAEQEQMRKILYQKESNYNRLKRAKMDKSM 667
QH++ +K +++ + +LQ E ++ G A+ + + + N+ R +R
Sbjct: 1790 QHIQEEVKMLERQRDAQLQ---EKSRIGRVAAKPREPDYRINVRRVNF-RWQRGN----- 1638
Query: 668 FVKIKTLGIGAFGEVCLACKVDTHALYAMKTLRKKDVLNRNQVAHVKAERDILAEADNEW 727
+G G FG+V A + T L A+K ++ + + Q+ + E I +E
Sbjct: 1637 -----KIGEGQFGKVYTAVNMSTGELMALKEMKFQPN-DLQQLREMCDEIKIFEGIQHEN 1476
Query: 728 VVKLYYSFQDKDSLYFVMDYIPGGDMMSLLIRMEVFPEHLARFYIAELTLAIESVHKMGF 787
+VK Y KD + M+Y G + +M + PE+L R Y E+ LA+ +H+
Sbjct: 1475 LVKYYGVEVHKDEMLMFMEYCDTGTIEEA-AKMGL-PEYLIRRYTREIVLAVNHLHENSI 1302
Query: 788 IHRDIKPDNILIDLDGHIKLTDFGLCTGFRWTHNSKYYQKGSHVRQDSMEPSDLWDDVSN 847
+HRDIK NI + +GH+KL DFG + SH + P +
Sbjct: 1301 VHRDIKGANIFLTSNGHVKLGDFGCSVKLK-----------SH----TTMPGEF------ 1185
Query: 848 CRCGDRLKTLEQRARKQHQRCLAHSLVGTPNYIAPEVLLRK---GYTQLCDWWSVGVILF 904
H+LVGT Y+APEV + GY + D WS+G ++
Sbjct: 1184 -----------------------HNLVGTTAYMAPEVFTQNDQGGYGRAADIWSLGCVVI 1074
Query: 905 EMLVGQPPF 913
EM G+ P+
Sbjct: 1073 EMATGKRPW 1047
>00486
Length = 797
Score = 86.7 bits (213), Expect = 5e-17, Method: Compositional matrix adjust.
Identities = 52/140 (37%), Positives = 80/140 (57%), Gaps = 5/140 (3%)
Frame = -2
Query: 869 LAHSLVGTPNYIAPEVLLRKGYTQLCDWWSVGVILFEMLVGQPPFLAPTPTETQLKVINW 928
+ H+ GT Y+APE+L R G+ + DWWS+G ++++ML G PPF A +T K++
Sbjct: 790 VTHTFCGTIEYMAPEILTRTGHGKAVDWWSLGALMYDMLTGSPPFTAENRKKTIDKIL-- 617
Query: 929 ENTLHIPAQVKLSPEARDLITKLC-CSADHRLGRNGADD---LKAHPFFSAIDFS-SDIR 983
+ L++P L+ EAR LI KL + RLG G DD +K H FF +++ +R
Sbjct: 616 KGKLNLPPY--LTNEARGLIKKLLRKNPAERLG-GGHDDSGPIKDHQFFRNTNWALLALR 446
Query: 984 KQPAPYVPTISHPMDTSNFD 1003
+ P+ P ++ DTS FD
Sbjct: 445 RAEPPFRPNVTSDEDTSQFD 386
>09606
Length = 1300
Score = 80.9 bits (198), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 58/242 (23%), Positives = 112/242 (46%)
Frame = -3
Query: 688 VDTHALYAMKTLRKKDVLNRNQVAHVKAERDILAEADNEWVVKLYYSFQDKDSLYFVMDY 747
++ A++ ++ ++ +V N ++ H + + VV+ + ++ + L+ V++
Sbjct: 1040 INFVAIHCIEKCKRPEVTNTVRMTHDISHPN---------VVQFHEWYETSNHLWLVVEL 888
Query: 748 IPGGDMMSLLIRMEVFPEHLARFYIAELTLAIESVHKMGFIHRDIKPDNILIDLDGHIKL 807
GG + +L + PE R + L + +H +G + D++P +L+D G +K
Sbjct: 887 CTGGSLADILAQDHHLPETSIRDFGIHLVTGLHYIHSLGILFHDLRPSKVLLDTSGVLKF 708
Query: 808 TDFGLCTGFRWTHNSKYYQKGSHVRQDSMEPSDLWDDVSNCRCGDRLKTLEQRARKQHQR 867
DFGL S V +++E +L+ + GD+ Q A + ++
Sbjct: 707 ADFGL----------------SKVEGENLE--ELFFKFA--EAGDQWNI--QSAEEMMKQ 594
Query: 868 CLAHSLVGTPNYIAPEVLLRKGYTQLCDWWSVGVILFEMLVGQPPFLAPTPTETQLKVIN 927
G+P Y+APEV + + D W++G + +EM G PPFL T T+ KV+N
Sbjct: 593 V---PTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSGHPPFLGETYDITKDKVLN 423
Query: 928 WE 929
E
Sbjct: 422 KE 417
>13592
Length = 980
Score = 79.7 bits (195), Expect = 6e-15, Method: Compositional matrix adjust.
Identities = 67/244 (27%), Positives = 103/244 (42%), Gaps = 4/244 (1%)
Frame = +2
Query: 674 LGIGAFGEVCLACKVDTHALYAMKTLRKKDVLNRNQVAHVKAERDILAEADNEWVVKLYY 733
+G G FG+V A +T L AMK + + R + +V E IL ++ +V+ Y
Sbjct: 8 IGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETR-ALKNVAEELKILEGIKHKNLVRYYG 184
Query: 734 SFQDKDSLYFVMDYIPGGDMMSLLIRMEVFPEHLARFYIAELTLAIESVHKMGFIHRDIK 793
++ L M+ G + SL+ PE L+R + A+L + +HK G +HRDIK
Sbjct: 185 IEVHREELLIFMELCSEGTLESLVELTGGLPEALSRRFTAQLLSGVAELHKHGIVHRDIK 364
Query: 794 PDNI-LIDLDGHIKLTDFGLCTGFRWTHNSKYYQKGSHVRQDSMEPSDLWDDVSNCRCGD 852
NI L+D +KL DFG ++ + P +L
Sbjct: 365 TANIFLVDGSNSLKLGDFG---------------SAVKIQAHTTVPGEL----------- 466
Query: 853 RLKTLEQRARKQHQRCLAHSLVGTPNYIAPEVLLRK---GYTQLCDWWSVGVILFEMLVG 909
VGT Y+APEV + G+ +L D WSVG ++ EM G
Sbjct: 467 ------------------QGYVGTQAYMAPEVFTKTNSDGHGRLADIWSVGCVVVEMASG 592
Query: 910 QPPF 913
+ P+
Sbjct: 593 KRPW 604
>18921
Length = 697
Score = 79.0 bits (193), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 62/251 (24%), Positives = 108/251 (43%), Gaps = 1/251 (0%)
Frame = +2
Query: 665 KSMFVKIKTLGIGAFGEVCLACKVDTHALYAMKTLRKKDVLNRNQVAHVKAERDILAEAD 724
+ +F + LG G++G V + +T + A+K V + + E I+ + D
Sbjct: 26 EDVFDILGKLGEGSYGSVFKSLHKETGQVLAIK-----QVPVDTDLQEIIKEISIMQQCD 190
Query: 725 NEWVVKLYYSFQDKDSLYFVMDYIPGGDMMSLL-IRMEVFPEHLARFYIAELTLAIESVH 783
++++VK Y S+ L+ VM+Y G + ++ +R + E + + +H
Sbjct: 191 SKYIVKYYGSYFKNTDLWIVMEYCGAGSVSDIMRLRNKTLVEREIATILYYTLKGLXYLH 370
Query: 784 KMGFIHRDIKPDNILIDLDGHIKLTDFGLCTGFRWTHNSKYYQKGSHVRQDSMEPSDLWD 843
IHRDIK NIL++ +GH KL DFG+
Sbjct: 371 SRRKIHRDIKAGNILLNNEGHAKLADFGV------------------------------- 457
Query: 844 DVSNCRCGDRLKTLEQRARKQHQRCLAHSLVGTPNYIAPEVLLRKGYTQLCDWWSVGVIL 903
G T+ +R ++++GTP ++APEV+ GY + D WS+G+
Sbjct: 458 ------AGQLTDTMAKR----------NTVIGTPYWMAPEVIQEIGYDCVADIWSLGITA 589
Query: 904 FEMLVGQPPFL 914
EM G+PP +
Sbjct: 590 LEMAEGKPPVM 622
>26560
Length = 398
Score = 77.0 bits (188), Expect = 4e-14, Method: Compositional matrix adjust.
Identities = 47/153 (30%), Positives = 69/153 (45%), Gaps = 1/153 (0%)
Frame = -1
Query: 762 VFPEHLARFYIAELTLAIESVHKMGFIHRDIKPDNILIDLDGHIKLTDFGLCTGFRWTHN 821
VF E RFY AE+ L +E +H ++RD+KP NIL+D +GH++++D GL
Sbjct: 368 VFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGLAC------- 210
Query: 822 SKYYQKGSHVRQDSMEPSDLWDDVSNCRCGDRLKTLEQRARKQHQRCLAHSLVGTPNYIA 881
D S R H+ VGT Y+A
Sbjct: 209 ----------------------DFSKKR--------------------PHASVGTHGYMA 156
Query: 882 PEVLLR-KGYTQLCDWWSVGVILFEMLVGQPPF 913
PEVL++ + Y DW+S G +L+++L G PF
Sbjct: 155 PEVLMKGQSYDSSADWFSFGCMLYKLLKGHSPF 57
>26156
Length = 479
Score = 64.3 bits (155), Expect(2) = 7e-14, Method: Composition-based stats.
Identities = 35/115 (30%), Positives = 64/115 (55%), Gaps = 1/115 (0%)
Frame = -1
Query: 657 RLKRAKMDKSMFVKIKTLGIGAFGEVCLACKVDTHALYAMKTLRKKDVLNRNQVAHVKAE 716
R R K+ + F+ ++ +G G++ +V T +YAMK ++K+ V + + V+ E
Sbjct: 416 RQFRNKLGLTDFLLLRVIGRGSYAKVLQVEHKRTKRIYAMKVIKKELVNDDEDIDWVQTE 237
Query: 717 RDILAEADN-EWVVKLYYSFQDKDSLYFVMDYIPGGDMMSLLIRMEVFPEHLARF 770
+ + A N ++V L+ FQ + L+FV++++ GGD+M + R PE ARF
Sbjct: 236 KHVFETATNYPFLVGLHSCFQSESRLFFVIEFVNGGDLMFHMQRQRRLPEEHARF 72
Score = 32.0 bits (71), Expect(2) = 7e-14, Method: Composition-based stats.
Identities = 12/24 (50%), Positives = 18/24 (75%)
Frame = -3
Query: 770 FYIAELTLAIESVHKMGFIHRDIK 793
FY AE+ LA+ +HK G ++RD+K
Sbjct: 75 FYSAEICLALNFLHKRGIVYRDLK 4
>18663
Length = 600
Score = 75.9 bits (185), Expect = 8e-14, Method: Compositional matrix adjust.
Identities = 53/150 (35%), Positives = 71/150 (47%), Gaps = 19/150 (12%)
Frame = +2
Query: 872 SLVGTPNYIAPEVLLRKGYTQLCDWWSVGVILFEMLVGQPPF----LAPTP---TETQLK 924
+ GTPNYIAPE+L + Y DWW++GV+L+EML G+ PF + P TE L
Sbjct: 5 TFCGTPNYIAPEILRGEDYGFSVDWWALGVLLYEMLAGRSPFDIAGASENPDQNTEDYLF 184
Query: 925 VINWENTLHIPAQVKLSPEARDLITKLCCSADHRLGRNGAD-----------DLKAHPFF 973
+ E T+ IP R L K L +N AD D+ HPFF
Sbjct: 185 QVILEKTIRIP---------RSLSVKAASVLKGFLNKNPADRLGCHRESAFMDIVNHPFF 337
Query: 974 SAIDFSSDIRKQPA-PYVPTISHPMDTSNF 1002
ID+ RKQ + P+ P + D +NF
Sbjct: 338 KVIDWEMLERKQVSPPFKPRLDSDRDLANF 427
>15910
Length = 1361
Score = 71.2 bits (173), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 51/183 (27%), Positives = 77/183 (42%), Gaps = 3/183 (1%)
Frame = +2
Query: 772 IAELTLAIESVHKMGFIHRDIKPDNILIDL---DGHIKLTDFGLCTGFRWTHNSKYYQKG 828
I+++ ++ +H G +HRD+KP+N+L + D +KL DFGL
Sbjct: 482 ISDILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLADFGL---------------- 613
Query: 829 SHVRQDSMEPSDLWDDVSNCRCGDRLKTLEQRARKQHQRCLAHSLVGTPNYIAPEVLLRK 888
S + + ++ S ++ GTP Y APEVL
Sbjct: 614 SRIIEPEVQMS--------------------------------TVCGTPGYCAPEVLKGD 697
Query: 889 GYTQLCDWWSVGVILFEMLVGQPPFLAPTPTETQLKVINWENTLHIPAQVKLSPEARDLI 948
YT D WSVGVI + +L G PF A E K+I E ++S A+D++
Sbjct: 698 KYTPSVDMWSVGVIAYILLCGYEPFFAENEFEMYRKIIKGEYKFDEEYWSEISENAKDVV 877
Query: 949 TKL 951
KL
Sbjct: 878 RKL 886
>17932
Length = 597
Score = 56.6 bits (135), Expect(2) = 1e-11, Method: Compositional matrix adjust.
Identities = 33/77 (42%), Positives = 47/77 (61%)
Frame = -3
Query: 934 IPAQVKLSPEARDLITKLCCSADHRLGRNGADDLKAHPFFSAIDFSSDIRKQPAPYVPTI 993
+P +S EARDLI++L RLG +L+ HPFF +D++ +IR PYVP+I
Sbjct: 478 VPPHSSVSKEARDLISQLLSDGKSRLG---WPELQQHPFFKTVDWA-NIRNAMPPYVPSI 311
Query: 994 SHPMDTSNFDPVDEESP 1010
S DTS+FD V++ P
Sbjct: 310 SSLDDTSHFDEVEKARP 260
Score = 32.0 bits (71), Expect(2) = 1e-11, Method: Composition-based stats.
Identities = 15/47 (31%), Positives = 25/47 (53%), Gaps = 2/47 (4%)
Frame = -2
Query: 896 WWSVGVILFEMLVGQPPFLAP--TPTETQLKVINWENTLHIPAQVKL 940
WWS+GV +EML G PF + T ++N++ P+Q ++
Sbjct: 596 WWSLGVCAYEMLFGCTPFTDDDGSMVATYNNIMNYKTNSSSPSQQRV 456
>17975
Length = 449
Score = 66.6 bits (161), Expect = 5e-11, Method: Composition-based stats.
Identities = 45/138 (32%), Positives = 70/138 (50%), Gaps = 2/138 (1%)
Frame = +3
Query: 679 FGEVCLACKVDTHALYAMKTLRKKDVLNRNQVAHVKAERDILAEADNEWVVKLYYSFQDK 738
F V LA V T A+K + K L+ +H+ E + + VV+LY +
Sbjct: 6 FAVVKLARHVFTGEKVAVKVIDKTK-LDEVSRSHLFQEVRCMKLVQHPNVVRLYEVIDTQ 182
Query: 739 DSLYFVMDYIPGGDMMSLLIRMEV-FPEHLARFYIAELTLAIESVHKMGFIHRDIKPDNI 797
LY +++ GGDM ++R E LA+ Y ++ AI HK+ +HRD+KP+N+
Sbjct: 183 TKLYLILELGDGGDMYDYIMRHSGGLEEKLAKRYFRQIVEAISYCHKLHVVHRDLKPENV 362
Query: 798 L-IDLDGHIKLTDFGLCT 814
+ + G +KLTDFG T
Sbjct: 363 VFFEKPGLVKLTDFGFST 416
>21079
Length = 878
Score = 63.2 bits (152), Expect = 5e-10, Method: Composition-based stats.
Identities = 49/200 (24%), Positives = 85/200 (42%), Gaps = 8/200 (4%)
Frame = +1
Query: 728 VVKLYYSFQDKDSLYFVMDYIPGGDMMSLLIRME-VFPEHLARFYIAELTLAIESVHKMG 786
++ L+ +F+ ++ VM+++ G++ +IR + V E ++ ++ + +H
Sbjct: 10 LLMLWDAFEAPRTMVLVMEFVGAGELFERVIRDDFVLTERDCVHFVRQICSGVGYMHTQS 189
Query: 787 FIHRDIKPDNILI--DLDGHIKLTDFGLCTGFRWTHNSKYYQKGSHVRQDSMEPSDLWDD 844
+H D+KP+N+L D IK+ DFGL +++Y+ G DS++
Sbjct: 190 ILHLDLKPENVLCVSDNSNQIKIIDFGL---------ARFYKPG-----DSLQ------- 306
Query: 845 VSNCRCGDRLKTLEQRARKQHQRCLAHSLVGTPNYIAPEVLLRKGYTQLCDWWSVGVILF 904
L GTP +IAPEV+ D WS+GVI +
Sbjct: 307 ---------------------------VLFGTPEFIAPEVVNYDEINFTTDMWSIGVICY 405
Query: 905 EMLVGQPP-----FLAPTPT 919
+L G P L P PT
Sbjct: 406 ILLSGLSPSRVTTMLRPWPT 465
>13212
Length = 1067
Score = 63.2 bits (152), Expect = 5e-10, Method: Compositional matrix adjust.
Identities = 61/230 (26%), Positives = 94/230 (40%), Gaps = 7/230 (3%)
Frame = -1
Query: 751 GDMMSLLIRMEV-FPEHLARFYIAELTLAIESVHKMGFIHRDIKPDNILIDLDGHIKLTD 809
G + S+++ +E E + E+ +A++ +H+ IHRDIK N+L+ +DG +KL D
Sbjct: 1028 GALDSIMVDLEKPMTEAQICYVCHEMCMALDFLHRHHVIHRDIKAGNVLLTIDGEVKLAD 849
Query: 810 FGLCTGFRWTHNSKYYQKGSHVRQDSMEPSDLWDDVSNCRCGDRLKTLEQRARKQHQRCL 869
FG+ N++ QK
Sbjct: 848 FGVSAK-----NTQTQQKRD---------------------------------------- 804
Query: 870 AHSLVGTPNYIAPEVLLRKG-----YTQLCDWWSVGVILFEMLVGQPPFLAPTPTETQLK 924
+ +GTP ++APEV+L + Y D WS+GV L E +PP P +K
Sbjct: 803 --TFIGTPYWMAPEVVLCETLKDTPYDFKADIWSLGVTLIEFAQIEPPNKEMHPMRVLIK 630
Query: 925 VINWE-NTLHIPAQVKLSPEARDLITKLCCSADHRLGRNGADDLKAHPFF 973
+ + TL P K + +D I K C D L R A +L HPF
Sbjct: 629 IHKSDPPTLEKPK--KWTKLFKDFIAK-CLVKDPNL-RPTAAELLEHPFM 492
>01707
Length = 757
Score = 62.0 bits (149), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 69/257 (26%), Positives = 106/257 (41%), Gaps = 8/257 (3%)
Frame = +1
Query: 662 KMDKSMFVKIKTLGIGAFGEVCLACKVDTHALYAMKTLRKKDVLNRNQVAHVKAERDI-- 719
+M+K + KI +G G++G V +T L A+K + + + + A R+I
Sbjct: 58 RMEK--YEKIGKIGEGSYGVVFKCRNKETSQLVAIKKFVESE---DDPLIKKIAMREIRM 222
Query: 720 LAEADNEWVVKLYYSFQDKDSLYFVMDYIPGGDMMSLLIRMEVFPEHLARFYIAELTLAI 779
L + + +V+L F+ K L+ V DY+ + L PE + + I + LA+
Sbjct: 223 LKQLKHPNLVRLIEVFRRKKRLHLVFDYVDHTLLNELDRYPRGLPEPMVKRIIYQTLLAV 402
Query: 780 ESVHKMGFIHRDIKPDNILIDLDGHIKLTDFG---LCTGFRWTHNSKYYQKGSHVRQDSM 836
H+ IHRD+KP+NILI G +KL DFG + TG
Sbjct: 403 NFCHQYNTIHRDVKPENILITRQGQVKLCDFGFARILTG--------------------- 519
Query: 837 EPSDLWDDVSNCRCGDRLKTLEQRARKQHQRCLAHSLVGTPNYIAPEVLLRKGYTQL--- 893
P D + D V T Y APE+L+ G TQ
Sbjct: 520 -PGDEYTD----------------------------YVATRWYRAPELLV--GDTQYGPP 606
Query: 894 CDWWSVGVILFEMLVGQ 910
D W++G + E+L GQ
Sbjct: 607 VDVWAIGCVFAELLTGQ 657
>01060
Length = 1800
Score = 58.9 bits (141), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 66/279 (23%), Positives = 109/279 (39%), Gaps = 11/279 (3%)
Frame = +1
Query: 658 LKRAKMD----KSMFVKIKTLGIGAFGEVCLACKVDTHALYAMKTLRKKDVLNRNQVAHV 713
+KR MD S + +G G +G V T AMK +R + + + +
Sbjct: 37 IKRLMMDFETALSDLTDFQKIGEGTYGVVYKCRHRATGRKLAMKKIRLRGSEDGVPSSAI 216
Query: 714 KAERDILAEADNEWVVKLYYSFQDKDSLYFVMDYIPGGDMMSLLIRMEVFPE------HL 767
+ E +L E + +V L + + L+ V +++ M L + ++ FPE L
Sbjct: 217 R-EIAMLRELRHTNIVCLEDVIMEDERLFLVFEFLS----MDLKMYIDKFPEGVVLDRRL 381
Query: 768 ARFYIAELTLAIESVHKMGFIHRDIKPDNILIDLDGHIKLTDFGLCTGFRWTHNSKYYQK 827
+ Y+ ++ I H+ +HRD+KP N+LI+ G IK+ DFG+ F
Sbjct: 382 VKSYVFQIVTGIXFCHQRRIVHRDLKPQNLLINHTGAIKIADFGMARTF----------- 528
Query: 828 GSHVRQDSMEPSDLWDDVSNCRCGDRLKTLEQRARKQHQRCLAHSLVGTPNYIAPEVLL- 886
VR + E LW Y APE+L+
Sbjct: 529 ALPVRAYTHEVVTLW------------------------------------YRAPEILMG 600
Query: 887 RKGYTQLCDWWSVGVILFEMLVGQPPFLAPTPTETQLKV 925
Y+ D WS+G I +ML+ P F + + K+
Sbjct: 601 ASKYSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKI 717
>33586
Length = 551
Score = 47.4 bits (111), Expect(2) = 1e-08, Method: Composition-based stats.
Identities = 18/49 (36%), Positives = 34/49 (69%)
Frame = +2
Query: 727 WVVKLYYSFQDKDSLYFVMDYIPGGDMMSLLIRMEVFPEHLARFYIAEL 775
++V L+Y+FQ + LY +++++ GGD+ + L + +F E +FY+AEL
Sbjct: 404 FIVHLHYAFQTEGKLYLILEFLRGGDLFTRLSKEVMFTEEDVKFYLAEL 550
Score = 30.8 bits (68), Expect(2) = 1e-08, Method: Composition-based stats.
Identities = 16/41 (39%), Positives = 26/41 (63%)
Frame = +3
Query: 689 DTHALYAMKTLRKKDVLNRNQVAHVKAERDILAEADNEWVV 729
D LYAMK L+K + R++ K ERDILA+ ++ +++
Sbjct: 291 DAGTLYAMKVLKKATLKVRDR-QRTKMERDILADVNHPFLL 410
>01756
Length = 1858
Score = 57.4 bits (137), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 78/291 (26%), Positives = 119/291 (40%), Gaps = 14/291 (4%)
Frame = -3
Query: 650 QKESNYNRLKRAKMDK-SMFVKIKTLGIGAFGEVCLACKVDTHALYAMKTLRKKDVLNRN 708
Q+ S Y LK D+ + + K+ +G G FGEV A T + AMK K + N
Sbjct: 1793 QRYSPYETLKFPFCDEDAKYEKLAKIGQGTFGEVFKARCKKTKQVVAMK---KVLMDNEK 1623
Query: 709 QVAHVKAERDI--LAEADNEWVVKLYYSFQDK-------DSLYFVMDYIPGGDMMSLLIR 759
+ + A R+I L ++E VV L K S+++++ D+ LL
Sbjct: 1622 EGFPITALREIKILQLLNHENVVDLIEICSTKATSANRYKSMFYLVFEFCEHDLAGLLSN 1443
Query: 760 MEV---FPEHLARFYIAELTLAIESVHKMGFIHRDIKPDNILIDLDGHIKLTDFGLCTGF 816
M V PE + + +L + +H+ +HRD+K NILI G +KL DFGL F
Sbjct: 1442 MSVVFNLPE--IKEVMKQLMNGLYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAF 1269
Query: 817 RWTHNSKYYQKGSHVRQDSMEPSDLWDDVSNCRCGDRLKTLEQRARKQHQRCLAHSLVGT 876
++RQ + R +R+ TL R
Sbjct: 1268 -----------SVNLRQPN-------------RYTNRVVTLWYR---------------- 1209
Query: 877 PNYIAPEVLL-RKGYTQLCDWWSVGVILFEMLVGQPPFLAPTPTETQLKVI 926
PE+LL + Y+ D W G I+ EM + P + T + QL +I
Sbjct: 1208 ----PPELLLGDRNYSTAIDQWGAGCIMAEMWT-RNPIMQGTTEQNQLTLI 1071
>01392
Length = 1806
Score = 57.0 bits (136), Expect = 4e-08, Method: Compositional matrix adjust.
Identities = 47/157 (29%), Positives = 67/157 (42%), Gaps = 8/157 (5%)
Frame = -1
Query: 765 EHLARFYIAELTLAIESVHKMGFIHRDIKPDNILID-LDGHI--KLTDFGLCTGFRWTHN 821
E A + + A++ +H G HRD+KP+NIL + LD + K+ DF L +G
Sbjct: 1794 EREASLVVRHIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGI----- 1630
Query: 822 SKYYQKGSHVRQDSMEPSDLWDDVSNCRCGDRLKTLEQRARKQHQRCLAHSLVGTPNYIA 881
+C GD KT E + VG+ Y+A
Sbjct: 1629 -------------------------SCD-GDGTKTPELL-----------TPVGSAEYMA 1561
Query: 882 PEVLL-----RKGYTQLCDWWSVGVILFEMLVGQPPF 913
PEV+ Y + CD WS+G+IL+ ML G PPF
Sbjct: 1560 PEVVDAWVGDSFSYDKRCDLWSLGIILYIMLCGYPPF 1450
>16708
Length = 1397
Score = 55.5 bits (132), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 42/151 (27%), Positives = 71/151 (47%), Gaps = 9/151 (5%)
Frame = -1
Query: 671 IKTLGIGAFGEVCLACKVDTHALYAMKTLRKKDVLNRNQVAHVKAERDI-----LAEADN 725
++ LG G FG+V A + TH A+KT +L + + V+A I LA+
Sbjct: 1388 LQVLGKGVFGKVYEARLLSTHEKAALKT----SILCHHSLDEVEALGRIEGGFYLAQMFG 1221
Query: 726 EWVVKLYYSFQDKDSLYFVMDYIPGGDMMSLLIRMEV----FPEHLARFYIAELTLAIES 781
WV L F + L + P ++ + E+ + + A+E
Sbjct: 1220 AWVTCL--PFPKMNILLHFYEMGPLCNVYAHYKNKEMPIRWSNPAMVCCIAGQXVCALEH 1047
Query: 782 VHKMGFIHRDIKPDNILIDLDGHIKLTDFGL 812
+H++G +H D+K DN+L+D G+ KLTD+G+
Sbjct: 1046 IHELGVVHMDVKADNVLVDAHGNCKLTDYGI 954
>21433
Length = 590
Score = 54.7 bits (130), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 51/181 (28%), Positives = 78/181 (43%)
Frame = +2
Query: 771 YIAELTLAIESVHKMGFIHRDIKPDNILIDLDGHIKLTDFGLCTGFRWTHNSKYYQKGSH 830
YI +L+ A+E H IHRDIKP+N+L+ L G +K+ DFG W+ ++ ++ +
Sbjct: 182 YIYQLSSALEYCHYRKVIHRDIKPENLLLGLKGDLKIADFG------WSVHAPSSRRTT- 340
Query: 831 VRQDSMEPSDLWDDVSNCRCGDRLKTLEQRARKQHQRCLAHSLVGTPNYIAPEVLLRKGY 890
+ GT +Y+ PE++ K +
Sbjct: 341 ------------------------------------------MCGTLDYLPPEMVEGKTH 394
Query: 891 TQLCDWWSVGVILFEMLVGQPPFLAPTPTETQLKVINWENTLHIPAQVKLSPEARDLITK 950
+ D WS+GV+ +E LVG PP W T P+ V +P ARDLI+K
Sbjct: 395 DENVDLWSLGVLCYEFLVGTPPLRPSPTRPPTPASPRW--TSGSPSIV--TPGARDLISK 562
Query: 951 L 951
L
Sbjct: 563 L 565
>02638
Length = 1490
Score = 54.7 bits (130), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 34/103 (33%), Positives = 53/103 (51%), Gaps = 1/103 (0%)
Frame = +1
Query: 873 LVGTPNYIAPEVLLRKGYTQLCDWWSVGVILFEMLVGQPPFLAPTPTETQLKVINWENTL 932
L+GT ++APEVL + Y + CD WSVG ++ EM +PP+ + + + +++
Sbjct: 16 LLGTIAFMAPEVLRGESYGRACDVWSVGCVMIEMCTCRPPWNSHDISNHLALIFKIASSV 195
Query: 933 H-IPAQVKLSPEARDLITKLCCSADHRLGRNGADDLKAHPFFS 974
P +SP RDL+ + C D R A DL HP F+
Sbjct: 196 DPPPIPENMSPPVRDLMLR-CLEQDSDF-RPSAKDLLMHPLFT 318
>19094
Length = 898
Score = 54.7 bits (130), Expect = 2e-07, Method: Composition-based stats.
Identities = 36/128 (28%), Positives = 53/128 (41%)
Frame = +1
Query: 782 VHKMGFIHRDIKPDNILIDLDGHIKLTDFGLCTGFRWTHNSKYYQKGSHVRQDSMEPSDL 841
+H IHRDIK NIL++ +GH KL DFG+
Sbjct: 106 LHSRRKIHRDIKAGNILLNNEGHAKLADFGVA---------------------------- 201
Query: 842 WDDVSNCRCGDRLKTLEQRARKQHQRCLAHSLVGTPNYIAPEVLLRKGYTQLCDWWSVGV 901
G T+ +R ++++GTP ++APEV+ GY + D WS+G+
Sbjct: 202 ---------GQLTDTMAKR----------NTVIGTPYWMAPEVIQEIGYDCVADIWSLGI 324
Query: 902 ILFEMLVG 909
EM G
Sbjct: 325 TALEMAEG 348
>13066
Length = 551
Score = 54.3 bits (129), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 25/97 (25%), Positives = 52/97 (53%)
Frame = +3
Query: 716 ERDILAEADNEWVVKLYYSFQDKDSLYFVMDYIPGGDMMSLLIRMEVFPEHLARFYIAEL 775
E D+L + D+ ++++++ Q + M + GD+++ + + E A+ + ++
Sbjct: 126 ELDLLTKLDHPYIIQIHSILQRXPKNFIFMRFAERGDLLTYIQEVGFVKEKQAKIWFYQM 305
Query: 776 TLAIESVHKMGFIHRDIKPDNILIDLDGHIKLTDFGL 812
T A+ +H HRD+K +NIL+ ++KL DFG
Sbjct: 306 TTALNYLHSYDVAHRDLKCENILLSSHFNVKLADFGF 416
>01966
Length = 1735
Score = 54.3 bits (129), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 31/107 (28%), Positives = 54/107 (50%), Gaps = 6/107 (5%)
Frame = -1
Query: 716 ERDILAEADNEWVVKLYYSFQDKDSLYFVMDYIPGGDMMSLLIRMEVFPE------HLAR 769
E +L E + +V L + + L+ V +++ M L + ++ FPE L +
Sbjct: 1564 EIAMLRELRHTNIVCLEDVIMEDERLFLVFEFLS----MDLKMYIDKFPEGVVLDRRLVK 1397
Query: 770 FYIAELTLAIESVHKMGFIHRDIKPDNILIDLDGHIKLTDFGLCTGF 816
Y+ ++ I H+ +HRD+KP N+LI+ G IK+ DFG+ F
Sbjct: 1396 SYVFQIVTGINFCHQRRIVHRDLKPQNLLINHTGAIKIADFGMARTF 1256
>06405
Length = 1965
Score = 53.5 bits (127), Expect = 4e-07, Method: Compositional matrix adjust.
Identities = 55/258 (21%), Positives = 97/258 (37%), Gaps = 4/258 (1%)
Frame = +1
Query: 660 RAKMDKSMFVKIKTLGIGAFGEVCLACKVDTHALYAMKTLRKKDVLNRNQVAHVKAERDI 719
R +++++ LG G +G+V A + + A+KTL K+D + N E I
Sbjct: 241 RWEIERTEIAMKHRLGGGQYGDVYEAMWKRYNKIVAVKTL-KEDTMALNDFLE---EAAI 408
Query: 720 LAEADNEWVVKLYYSFQDKDSLYFVMDYIPGGDMMSLL---IRMEVFPEHLARFYIAELT 776
+ E + +V+L + Y V +++P G+++ L R E P L + ++
Sbjct: 409 MKEMKHPNLVQLLGVCTREPPFYIVTEFMPHGNLLDYLRSSTREENGPTALM-YMATQIA 585
Query: 777 LAIESVHKMGFIHRDIKPDNILIDLDGHIKLTDFGLCTGFRWTHNSKYYQKGSHVRQDSM 836
+ + FIHRD+ N L+ +K+ DFGL +
Sbjct: 586 SGMAYLETKNFIHRDLAARNCLVADSNMVKVADFGLARLMK------------------- 708
Query: 837 EPSDLWDDVSNCRCGDRLKTLEQRARKQHQRCLAHSLVGTPNYIAPEVLLRKGYTQLCDW 896
DD G + + APE L ++ D
Sbjct: 709 ------DDTYTAHIGAKFPI---------------------KWTAPEGLAFNRFSTRSDI 807
Query: 897 WSVGVILFEMLV-GQPPF 913
W+ GV+L+E+ G P+
Sbjct: 808 WAFGVLLWELATYGMSPY 861
>12786
Length = 460
Score = 53.1 bits (126), Expect = 6e-07, Method: Compositional matrix adjust.
Identities = 40/167 (23%), Positives = 65/167 (38%), Gaps = 20/167 (11%)
Frame = -3
Query: 767 LARFYIAELTLAIESVHKMGFIHRDIKPDNILIDLDGHIKLTDFGLCTGFRWTHNSKYYQ 826
+ +FY E+ A++++H G IH D+KP N ++ + G++KL DFG+
Sbjct: 407 MIKFYWREMLRAVKALHNEGVIHSDLKPANFML-VAGNLKLIDFGIAN------------ 267
Query: 827 KGSHVRQDSMEPSDLWDDVSNCRCGDRLKTLEQRARKQHQRCLAHSLVGTPNYIAPEVLL 886
TL+Q L S VGTP+Y++PE ++
Sbjct: 266 -----------------------------TLQQ----DKTSVLKDSRVGTPSYMSPEAIM 186
Query: 887 --------------------RKGYTQLCDWWSVGVILFEMLVGQPPF 913
+ D WS+G IL+ M+ G+ PF
Sbjct: 185 AACDDSADDSMEEDGHRTKPKYKVGVRSDVWSLGCILYNMVYGRTPF 45
>26711
Length = 405
Score = 52.8 bits (125), Expect = 8e-07, Method: Compositional matrix adjust.
Identities = 46/176 (26%), Positives = 71/176 (40%), Gaps = 6/176 (3%)
Frame = -2
Query: 779 IESVHKMGFIHRDIKPDNILIDLD--GHIKLTDFGLCTGFRWTHNSKYYQKGSHVRQDSM 836
++ VH G +H D+KP N+L+ D ++L DFGL
Sbjct: 377 LQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGL------------------------ 270
Query: 837 EPSDLWDDVSNCRCGDRLKTLEQRARKQH---QRCLAHSLVGTPNYIAPEVLLRKGYTQL 893
ARK + + L H GTP + +PE L K +
Sbjct: 269 ------------------------ARKLYPPQETFLNH---GTPGFTSPEALDVKPISTA 171
Query: 894 CDWWSVGVILFEMLVGQPPFLAPTPTETQLKVINWENTLHI-PAQVKLSPEARDLI 948
D W VGV+ + +L GQ PF A + TE+ K + + + P+ +S +A+D I
Sbjct: 170 SDVWGVGVLAYILLSGQSPFQADSATESLKKTQTCDWSFDVCPSFSNMSQDAKDFI 3
>25019
Length = 730
Score = 52.4 bits (124), Expect = 1e-06, Method: Composition-based stats.
Identities = 33/110 (30%), Positives = 43/110 (39%), Gaps = 4/110 (3%)
Frame = +3
Query: 795 DNILIDLDGHIKLTDFGLC----TGFRWTHNSKYYQKGSHVRQDSMEPSDLWDDVSNCRC 850
+N+L+D DGH+KLTDFGLC TG R TH
Sbjct: 261 ENVLLDKDGHVKLTDFGLCKEAITGTRVTH------------------------------ 350
Query: 851 GDRLKTLEQRARKQHQRCLAHSLVGTPNYIAPEVLLRKGYTQLCDWWSVG 900
+ GT Y+APE+L R G+ + DWWS+G
Sbjct: 351 ---------------------TFCGTIEYMAPEILTRTGHGKAVDWWSLG 437
>14126
Length = 1265
Score = 52.0 bits (123), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 82/362 (22%), Positives = 140/362 (38%), Gaps = 38/362 (10%)
Frame = +3
Query: 650 QKESNYNRLKRAKMDKSMFVKIKTLGIGAFGEVCLACKVDTHALY-AMKTLRKKDVLNRN 708
Q ES +R + + ++ +G GA+G V A + + AMK +R N
Sbjct: 141 QSESAAKMSRRRDSTEQKYEEVAVIGNGAYGTVYKARDLRNQGEFVAMKRIRLN---NTE 311
Query: 709 QVAHVKAERDI-----LAEADNEWVVKL----YYSFQDKD-SLYFVMDYIPGGDMMSLLI 758
+ + A R+I L + ++ VV+L + + D++ L V +YI D+ + L
Sbjct: 312 EGMPMMAIREISMLKQLEQYEHPNVVRLLDVSHNTITDREIRLNLVFEYIEH-DLATYLA 488
Query: 759 RM---EVFPEHLARFYIAELTLAIESVHKMGFIHRDIKPDNILIDLDGHIKLTDFGLCTG 815
+ + P+ + + +L ++ +H +HRD+KP N+LI DG +KL DFGL
Sbjct: 489 KCPSPGLGPDRIKDLML-QLLNGVDFLHSNRIVHRDLKPQNLLISKDGRLKLADFGL--- 656
Query: 816 FRWTHNSKYYQKGSHVRQDSMEPSDLWDDVSNCRCGDRLKTLEQRARKQHQRCLAHSLVG 875
AR ++V
Sbjct: 657 ---------------------------------------------ARIYSFHMALTTVVV 701
Query: 876 TPNYIAPEVLLRKGYTQLCDWWSVGVILFEMLVGQPPFLAPTPTETQLKVI--------- 926
T Y +PEVL++ Y D WS G I E+ + F + + QLK I
Sbjct: 702 TLWYRSPEVLMQAEYGTSVDIWSCGCIFAELFTRRALFKGSSEFD-QLKKIFEVIGLPPA 878
Query: 927 -NW-------ENTLH----IPAQV---KLSPEARDLITKLCCSADHRLGRNGADDLKAHP 971
+W N+ +P Q ++ P+A+DL+ K+ R R + + HP
Sbjct: 879 GDWPEGVSVHRNSFRPTPPVPLQTLVPEMDPQAKDLMEKMLVFKSGR--RISSRESLLHP 1052
Query: 972 FF 973
+
Sbjct: 1053YL 1058
>27546
Length = 426
Score = 51.6 bits (122), Expect = 2e-06, Method: Composition-based stats.
Identities = 25/97 (25%), Positives = 50/97 (51%)
Frame = -1
Query: 716 ERDILAEADNEWVVKLYYSFQDKDSLYFVMDYIPGGDMMSLLIRMEVFPEHLARFYIAEL 775
E +IL D+ +++++ Q ++ M Y GDM+S + + E + + ++
Sbjct: 330 ELEILTRLDHPNIIQIHSILQRGPKIFIFMRYAEKGDMLSHIKKTGPIDEAQTKVWFFQM 151
Query: 776 TLAIESVHKMGFIHRDIKPDNILIDLDGHIKLTDFGL 812
A++ +H HRD+K +NIL+ ++K+ DFG
Sbjct: 150 AKALQYLHSHDIAHRDLKCENILLSKRLNVKIADFGF 40
>03508
Length = 1463
Score = 51.2 bits (121), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 22/53 (41%), Positives = 36/53 (67%), Gaps = 1/53 (1%)
Frame = +1
Query: 761 EVFPEHLARFYIAELTLAIESVHKMGFIHRDIKPDNILIDLDG-HIKLTDFGL 812
+ F ++ RFY+ EL A++ H MG +HRD+KP N++ID + ++L D+GL
Sbjct: 856 QTFTDYDIRFYLYELMKALDFCHSMGIMHRDVKPHNVMIDHENKKLRLIDWGL 1014
>11185
Length = 473
Score = 51.2 bits (121), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 35/144 (24%), Positives = 60/144 (41%)
Frame = +1
Query: 775 LTLAIESVHKMGFIHRDIKPDNILIDLDGHIKLTDFGLCTGFRWTHNSKYYQKGSHVRQD 834
L + +H +G + D++P +L+D G +K DFGL S V +
Sbjct: 28 LVTGLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGL----------------SKVEGE 159
Query: 835 SMEPSDLWDDVSNCRCGDRLKTLEQRARKQHQRCLAHSLVGTPNYIAPEVLLRKGYTQLC 894
++E GD+ Q A + ++ G+P Y+APEV + +
Sbjct: 160 NLEELFF----KFAEAGDQWNI--QSAEEMMKQVPTS---GSPTYMAPEVFQGAEPSIMS 312
Query: 895 DWWSVGVILFEMLVGQPPFLAPTP 918
D W++G + +EM G P+P
Sbjct: 313 DLWALGCVFYEMFSGSRLSAKPSP 384
>29581
Length = 1278
Score = 51.2 bits (121), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 53/190 (27%), Positives = 77/190 (40%), Gaps = 2/190 (1%)
Frame = -2
Query: 739 DSLYFVMDYIPGGDMMSLLIRMEV-FPEHLARFYIAELTLAIESVHKMGFIHRDIKPDNI 797
DSL+ VM+Y D+ SLL M F E + + +L + +H+ IHRD+K N+
Sbjct: 1130 DSLFLVMEYCEQ-DLASLLDNMPAPFSESQVKCIVLQLLKGLRYLHEAFIIHRDLKVSNL 954
Query: 798 LIDLDGHIKLTDFGLCTGFRWTHNSKYYQKGSHVRQDSMEPSDLWDDVSNCRCGDRLKTL 857
L+ G +K+ DFGL ++ Y K Q M P
Sbjct: 953 LMTDKGCVKIADFGL---------ARNYGKP----QKPMTPK------------------ 867
Query: 858 EQRARKQHQRCLAHSLVGTPNYIAPEVLL-RKGYTQLCDWWSVGVILFEMLVGQPPFLAP 916
V T Y APE+L K ++ D WS G IL E+L G P +
Sbjct: 866 ----------------VVTLWYRAPELLFGSKTHSTAIDMWSAGCILGELL-GHKPLMPG 738
Query: 917 TPTETQLKVI 926
Q+++I
Sbjct: 737 RSDLQQIELI 708
>17722
Length = 680
Score = 50.4 bits (119), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 34/110 (30%), Positives = 56/110 (50%), Gaps = 4/110 (3%)
Frame = -3
Query: 894 CDWWSVGVILFEMLVGQPPFLAPTPTETQLKVINWENTLHIPAQVKLSPEARDLITKLCC 953
DWW GV+++EM+ G+ PF + ++I +N + LS EA+ L++ L
Sbjct: 678 VDWWGTGVVMYEMMCGRLPFYN-RDHDVLFELILLQN---VKFPRNLSEEAKTLLSGLLA 511
Query: 954 -SADHRLGRNGAD--DLKAHPFFSAIDFSS-DIRKQPAPYVPTISHPMDT 999
+ RLG + AD ++K HPFF I++ +K P+ P + DT
Sbjct: 510 KNPKRRLGGSEADVTEIKTHPFFQCINWDDLAAKKITPPWKPDVKSSWDT 361
>18401
Length = 463
Score = 48.9 bits (115), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 20/42 (47%), Positives = 28/42 (66%)
Frame = -3
Query: 872 SLVGTPNYIAPEVLLRKGYTQLCDWWSVGVILFEMLVGQPPF 913
++V T +Y APEV+L G++ CD WSVG I+FE+ G F
Sbjct: 455 TIVSTRHYRAPEVILELGWSHPCDVWSVGCIMFELYTGYTLF 330
>01718
Length = 959
Score = 47.4 bits (111), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 66/256 (25%), Positives = 99/256 (38%), Gaps = 18/256 (7%)
Frame = +3
Query: 674 LGIGAFGEV----------CLACKVDTHALYAMKTLRKKDVLNRNQVAHVKAERDILAEA 723
+G G F EV +A K++T LR+ +LNR Q A++
Sbjct: 171 IGAGFFSEVFKVTHRITGQVMALKMNTMTSNRHNMLREVQLLNRLQHANI---------- 320
Query: 724 DNEWVVKLYYSFQDKDSLYFVMDYIPGGDMMSLLIRMEVFPEHLARFYIAELTLAI---- 779
++ + L+ + +YIP G++ LL E E L +LTL +
Sbjct: 321 -----LRFMGVCVHEGQLHALTEYIPSGNLEQLL---EKKDEELPWTQRIQLTLGLARGL 476
Query: 780 ESVHKMGFIHRDIKPDNILI---DLDG-HIKLTDFGLCTGFRWTHNSKYYQKGSHVRQDS 835
+ +H FIHRD+ NILI D G H + DFGL T
Sbjct: 477 DYLHSTRFIHRDLTSKNILIRREDNHGYHAVIADFGLATKIP------------------ 602
Query: 836 MEPSDLWDDVSNCRCGDRLKTLEQRARKQHQRCLAHSLVGTPNYIAPEVLLRKGYTQLCD 895
+P D ++L T VG+P ++APEVL Y + D
Sbjct: 603 -DPLD----------KEKLPT-----------------VGSPYWMAPEVLNGHFYNERAD 698
Query: 896 WWSVGVILFEMLVGQP 911
+SVG+I+ E+ P
Sbjct: 699 LFSVGIIMCEITARIP 746
>37602
Length = 804
Score = 46.2 bits (108), Expect = 7e-05, Method: Compositional matrix adjust.
Identities = 26/82 (31%), Positives = 40/82 (48%)
Frame = -1
Query: 729 VKLYYSFQDKDSLYFVMDYIPGGDMMSLLIRMEVFPEHLARFYIAELTLAIESVHKMGFI 788
V + S+ ++ L+ M+Y GG M + E F E + +H+ G +
Sbjct: 330 VGYFDSYLRREKLWIAMEYCGGGSMQDIYHVTGPLTEPQIAFVCRETLKGLHYLHRRGKM 151
Query: 789 HRDIKPDNILIDLDGHIKLTDF 810
HRDIK NIL+ +G +KL DF
Sbjct: 150 HRDIKGANILLTEEGDVKLADF 85
>32957
Length = 645
Score = 45.4 bits (106), Expect = 1e-04, Method: Composition-based stats.
Identities = 18/39 (46%), Positives = 25/39 (64%)
Frame = +3
Query: 872 SLVGTPNYIAPEVLLRKGYTQLCDWWSVGVILFEMLVGQ 910
+ GT Y+APEV RK Y + DWW +G++L E+L Q
Sbjct: 42 TFCGTREYMAPEVHERKEYGKEVDWWGLGILLHELLAAQ 158
>04591
Length = 1117
Score = 45.4 bits (106), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 34/108 (31%), Positives = 53/108 (49%), Gaps = 11/108 (10%)
Frame = -2
Query: 716 ERDILAEADNEWVVKL----------YYSFQDKDSLYFVMDYIPGGDMMSLLIRMEV-FP 764
E IL + ++E VV+L Y + K + Y + +Y D+ LL + V F
Sbjct: 1071 EIKILQQLEHENVVQLQEICHTQAGPYNRY--KSTFYLIFEYC-DYDLAGLLNNLRVKFS 901
Query: 765 EHLARFYIAELTLAIESVHKMGFIHRDIKPDNILIDLDGHIKLTDFGL 812
+ +++L + +H +HRDIK NIL+ DG +KL DFGL
Sbjct: 900 LADKKNLMSQLLNGLFYIHTKQILHRDIKAANILLTRDGVLKLADFGL 757
>29590
Length = 320
Score = 45.1 bits (105), Expect = 2e-04, Method: Composition-based stats.
Identities = 23/63 (36%), Positives = 37/63 (58%), Gaps = 3/63 (4%)
Frame = +3
Query: 873 LVGTPNYIAPEVLLRKGYTQLCDWWSVGVILFEMLVGQPPFLAPTP---TETQLKVINWE 929
++GTP+Y+APEVL + + D WS+GV+ + ML PF+ T + T L+ NW
Sbjct: 54 IIGTPDYVAPEVLDYEPLSIQTDMWSLGVLSYVMLTACSPFVGITSKKHSATSLRS-NWT 230
Query: 930 NTL 932
+ +
Sbjct: 231 SQM 239
>17516
Length = 453
Score = 43.5 bits (101), Expect = 5e-04, Method: Compositional matrix adjust.
Identities = 22/43 (51%), Positives = 31/43 (72%), Gaps = 1/43 (2%)
Frame = -3
Query: 869 LAHSLVGTPNYIAPEVLLRKG-YTQLCDWWSVGVILFEMLVGQ 910
+A +L GTP Y+APEVLL+KG Y D +S+ +IL+E+ GQ
Sbjct: 451 IAGTLAGTPVYMAPEVLLQKGQYDMKADVYSLAIILWELWYGQ 323
>14477
Length = 493
Score = 43.5 bits (101), Expect = 5e-04, Method: Composition-based stats.
Identities = 41/158 (25%), Positives = 76/158 (48%), Gaps = 6/158 (3%)
Frame = -1
Query: 674 LGIGAFGEVCLA-CKVDTHAL-YAMKTLRKKDVLNRNQVAHVKAERDILAEADNEWVVKL 731
LG G FG V C++D + A+K L+ D+ Q +K E +++ + D+ +V+L
Sbjct: 466 LGAGNFGSVMKGVCRLDDREIPVAIKVLKNADLDPSVQSELIK-EAEVMKKMDHMHIVRL 290
Query: 732 YYSFQDKDSLYFVMDYIPGGDMMSLLIRMEVFPEHLARFYIAEL----TLAIESVHKMGF 787
+ +++ V++ G + L + +HL + I EL + +E + F
Sbjct: 289 I-GLCEGETMMLVLELAKLGPLNKFLPK----NKHLPLWNILELMWQVSQGMEYLEANKF 125
Query: 788 IHRDIKPDNILIDLDGHIKLTDFGLCTGFRWTHNSKYY 825
+HRD+ NIL+ + K++DFG+ +N YY
Sbjct: 124 VHRDLAARNILLCDEHFAKISDFGMSKTLSRENN--YY 17
>32359
Length = 928
Score = 35.4 bits (80), Expect(2) = 5e-04, Method: Compositional matrix adjust.
Identities = 28/89 (31%), Positives = 46/89 (51%), Gaps = 7/89 (7%)
Frame = -1
Query: 668 FVKIKTLGIGAFGEVCLACKVDTHALYAM-KTLRKKDVLNRNQVAHVKAERDILAEADNE 726
+ K +G G+FG V A VDT L A+ K L+ K NR E I+ + +++
Sbjct: 424 YTDAKVIGNGSFGVVYQAKLVDTSELVAIKKVLQDKRFKNR--------ELQIMRKLEHQ 269
Query: 727 WVVKLYYSF----QDKDSLY--FVMDYIP 749
+VKL + F + KD ++ V++Y+P
Sbjct: 268 NIVKLKFFFYSSGEKKDEVFLNLVLEYVP 182
Score = 27.3 bits (59), Expect(2) = 5e-04, Method: Composition-based stats.
Identities = 10/15 (66%), Positives = 12/15 (80%)
Frame = -3
Query: 786 GFIHRDIKPDNILID 800
G HRDIKP N+L+D
Sbjct: 65 GVCHRDIKPQNLLLD 21
>04138
Length = 800
Score = 43.1 bits (100), Expect = 5e-04, Method: Compositional matrix adjust.
Identities = 40/146 (27%), Positives = 58/146 (39%), Gaps = 1/146 (0%)
Frame = +1
Query: 782 VHKMGFIHRDIKPDNILIDLDGHIKLTDFGLCTGFRWTHNSKYYQKGSHVRQDSMEPSDL 841
+H+ +HRD+K NILI G +KL DFGL F ++RQ +
Sbjct: 61 IHRNKILHRDMKAANILITKQGVLKLADFGLARAF-----------SVNLRQPN------ 189
Query: 842 WDDVSNCRCGDRLKTLEQRARKQHQRCLAHSLVGTPNYIAPEVLL-RKGYTQLCDWWSVG 900
R +R+ TL R PE+LL + Y+ D W G
Sbjct: 190 -------RYTNRVVTLWYR--------------------PPELLLGDRNYSTAIDQWGAG 288
Query: 901 VILFEMLVGQPPFLAPTPTETQLKVI 926
I+ EM + P + T + QL +I
Sbjct: 289 CIMAEMWT-RNPIMQGTTEQNQLTLI 363
>28157
Length = 400
Score = 42.7 bits (99), Expect = 7e-04, Method: Compositional matrix adjust.
Identities = 29/91 (31%), Positives = 48/91 (52%), Gaps = 7/91 (7%)
Frame = +3
Query: 728 VVKLYYSFQDKDSLYFVMDYIPGGDMMSLLIRMEVFPEHLARF---YIAELTLAIESVHK 784
+V LY + +D + VM+Y GG + ++L P++ A ++ + L +E +H
Sbjct: 96 IVCLYGACRD-HPVCLVMEYAEGGSLYNVLHGSGPQPQYTAAHAMNWLLQCALGVEYLHG 272
Query: 785 M---GFIHRDIKPDN-ILIDLDGHIKLTDFG 811
M IHRD+KP N +LI +K+ DFG
Sbjct: 273 MKPKALIHRDLKPPNLLLIQCGTKLKICDFG 365
>28638
Length = 1458
Score = 42.7 bits (99), Expect = 7e-04, Method: Compositional matrix adjust.
Identities = 36/132 (27%), Positives = 50/132 (37%), Gaps = 2/132 (1%)
Frame = -1
Query: 784 KMGFIHRDIKPDNILID--LDGHIKLTDFGLCTGFRWTHNSKYYQKGSHVRQDSMEPSDL 841
+M IH D+KP+NIL+ IK+ DFG
Sbjct: 777 EMNIIHCDLKPENILLCNPKRSAIKIVDFG------------------------------ 688
Query: 842 WDDVSNCRCGDRLKTLEQRARKQHQRCLAHSLVGTPNYIAPEVLLRKGYTQLCDWWSVGV 901
S+C+ G R+ + + + Y +PEVLL Y D WS+G
Sbjct: 687 ----SSCQLGQRI----------------YQYIQSRFYRSPEVLLGVPYDLAIDMWSLGC 568
Query: 902 ILFEMLVGQPPF 913
IL EM G+PP
Sbjct: 567 ILVEMHTGEPPL 532
>00715
Length = 1788
Score = 42.7 bits (99), Expect = 7e-04, Method: Compositional matrix adjust.
Identities = 40/177 (22%), Positives = 74/177 (41%), Gaps = 1/177 (0%)
Frame = +1
Query: 738 KDSLYFVMDYIPGGDMMSLLIRMEVFPEHLARFYIA-ELTLAIESVHKMGFIHRDIKPDN 796
+D + M+Y+ ++ ++L + + R +A ++ + +H + +H D+KP N
Sbjct: 151 EDGAWLAMEYVGPLNLQTILNDHQQDIDSSMRLSLALQMARGLHYLHSINIVHLDLKPAN 330
Query: 797 ILIDLDGHIKLTDFGLCTGFRWTHNSKYYQKGSHVRQDSMEPSDLWDDVSNCRCGDRLKT 856
L+ D +++ DFG C + P+ L D+ G
Sbjct: 331 CLLTRDLKLRIADFGCC--------------------HQLTPTGL--DMGEREGGMAGNE 444
Query: 857 LEQRARKQHQRCLAHSLVGTPNYIAPEVLLRKGYTQLCDWWSVGVILFEMLVGQPPF 913
LE Q + L GT Y APE+L + D +S+G+ L++M Q P+
Sbjct: 445 LELTPV---QGAWKNELAGTLAYRAPELLKGLQPSVRSDVYSLGITLWQMCTRQGPY 606
>18481
Length = 437
Score = 41.6 bits (96), Expect = 0.002, Method: Composition-based stats.
Identities = 20/54 (37%), Positives = 32/54 (59%), Gaps = 3/54 (5%)
Frame = -1
Query: 774 ELTLAIESVHKMGFIHRDIKPDNILIDLDGH---IKLTDFGLCTGFRWTHNSKY 824
+L +E +H+ FIHRD+KPDN L+ L H + + DFGL ++ T + +
Sbjct: 173 QLLSRLEFIHQKCFIHRDLKPDNFLMGLGRHCHRLYIIDFGLSKRYKDTQGTMH 12
>04852
Length = 1462
Score = 41.6 bits (96), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 38/151 (25%), Positives = 57/151 (37%), Gaps = 1/151 (0%)
Frame = +1
Query: 771 YIAELTLAIESVHKMGFIHRDIKPDNILIDLDGHIKLTDFGLCTGFRWTHNSKYYQKGSH 830
Y ++ +E + IHRD+ N+L+ + +K+ DFGL + YY+K
Sbjct: 340 YAFQIARGMEFLASRKCIHRDLAARNVLVTEEHVLKIADFGL------SRTGDYYKK--- 492
Query: 831 VRQDSMEPSDLWDDVSNCRCGDRLKTLEQRARKQHQRCLAHSLVGTPNYIAPEVLLRKGY 890
R G RL ++APE L Y
Sbjct: 493 ------------------RSGGRLPV---------------------KWMAPEALFDMRY 555
Query: 891 TQLCDWWSVGVILFEML-VGQPPFLAPTPTE 920
T D WS GV+L+E+ +G P+ A P E
Sbjct: 556 TTKSDVWSFGVVLWEIFSLGGMPY-ASIPNE 645
>19301
Length = 712
Score = 41.6 bits (96), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 19/69 (27%), Positives = 36/69 (52%)
Frame = +2
Query: 743 FVMDYIPGGDMMSLLIRMEVFPEHLARFYIAELTLAIESVHKMGFIHRDIKPDNILIDLD 802
+M+Y P G + +L + P L + ++ + +H IHRD+K N+L+ +
Sbjct: 500 IIMEYCPYGQLYEVLRDGKEIPPALVLDWSKQIASGMNYLHSHKIIHRDLKSPNVLVAKN 679
Query: 803 GHIKLTDFG 811
+K++DFG
Sbjct: 680 DVVKISDFG 706
>19761
Length = 473
Score = 40.8 bits (94), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 33/146 (22%), Positives = 55/146 (37%), Gaps = 2/146 (1%)
Frame = -3
Query: 763 FPEHLARFYIAELTLAIESVHKMG--FIHRDIKPDNILIDLDGHIKLTDFGLCTGFRWTH 820
PE L ++ + A+ +H +HRD+KP NI + G ++L D GL
Sbjct: 432 LPERLIVCWLMQTASALNYMHTHTPVILHRDLKPQNIYVTEKGDVRLGDLGLA------- 274
Query: 821 NSKYYQKGSHVRQDSMEPSDLWDDVSNCRCGDRLKTLEQRARKQHQRCLAHSLVGTPNYI 880
+ P+D A S VGT Y+
Sbjct: 273 ------------RKLTGPADF----------------------------ATSQVGTIMYL 214
Query: 881 APEVLLRKGYTQLCDWWSVGVILFEM 906
+PE+L ++ Y D WS+G + +++
Sbjct: 213 SPEILSQQPYNSKSDIWSLGCVFYDI 136
>20152
Length = 445
Score = 40.8 bits (94), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 34/117 (29%), Positives = 55/117 (47%), Gaps = 1/117 (0%)
Frame = +1
Query: 882 PEVLLRKGYTQ-LCDWWSVGVILFEMLVGQPPFLAPTPTETQLKVINWENTLHIPAQVKL 940
PE+LL Y D WS+GVIL+ ++VG+ PF +ET +++ IP +
Sbjct: 1 PEILLGDSYDAPAVDVWSLGVILYMLVVGEAPFQEANDSETLTMIMDCRY--QIPPHI-- 168
Query: 941 SPEARDLITKLCCSADHRLGRNGADDLKAHPFFSAIDFSSDIRKQPAPYVPTISHPM 997
S + +DLI K+ + R + AHP+ + D + Y+P I+ M
Sbjct: 169 SHKCQDLIEKML--QREPVDRASLPHILAHPWLNDGDLTPT-----TAYLPLITKEM 318
>01106
Length = 878
Score = 40.8 bits (94), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 38/161 (23%), Positives = 71/161 (44%), Gaps = 10/161 (6%)
Frame = +3
Query: 652 ESNYNRLKRAKMDKSMFVKIKTLGIGAFGEVCLACKVDTHALYAMKTLRKKDVLNRNQVA 711
+ Y+ +K + + I+ LG G F V L + A+K ++ +
Sbjct: 276 KGGYHPVKNGDLFNGRYHVIRKLGWGHFSTVWLCWDLTCKRFVALKVVKSAQHYTETALD 455
Query: 712 HVKAERDI----LAEADNEWVVKLYYSFQDK--DSLYFVMDY-IPGGDMMSLLIR--MEV 762
VK + + +A+ V+L F+ + + M + + G +++ L+IR +
Sbjct: 456 EVKLLKCVRESDVADPARAKCVQLLDDFKISGVNGTHVAMVFEVLGYNLLKLIIRSNYQG 635
Query: 763 FPEHLARFYIAELTLAIESVH-KMGFIHRDIKPDNILIDLD 802
P H + I ++ + +H K IH DIKP+NILI +D
Sbjct: 636 IPIHNVKLIIRQVLEGLSYMHAKCRIIHTDIKPENILICVD 758
>21808
Length = 1011
Score = 39.7 bits (91), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 23/101 (22%), Positives = 48/101 (47%), Gaps = 3/101 (2%)
Frame = +1
Query: 715 AERDILAEADNEWVVKLYYSFQDKDSLYFVMDYIPGGDMMSLLI---RMEVFPEHLARFY 771
AE I+ + + +++LY D ++ + + + G ++ L R+ P +
Sbjct: 79 AEAQIMKKLRHPKLIQLYAVCTQDDPIFIITELMKNGSLLEFLQGKGRVLKLPALID--I 252
Query: 772 IAELTLAIESVHKMGFIHRDIKPDNILIDLDGHIKLTDFGL 812
A++ + + +IHRD+ NIL+ + +K+ DFGL
Sbjct: 253 GAQIACGMAYLESQNYIHRDLAARNILVSDNNTVKIADFGL 375
>00638
Length = 1595
Score = 38.9 bits (89), Expect = 0.011, Method: Compositional matrix adjust.
Identities = 15/34 (44%), Positives = 23/34 (67%)
Frame = +2
Query: 761 EVFPEHLARFYIAELTLAIESVHKMGFIHRDIKP 794
+ F ++ RFY+ EL A++ H MG +HRD+KP
Sbjct: 401 QTFTDYDIRFYLYELMKALDFCHSMGIMHRDVKP 502
>14116
Length = 1017
Score = 38.1 bits (87), Expect = 0.021, Method: Compositional matrix adjust.
Identities = 17/56 (30%), Positives = 31/56 (55%)
Frame = -1
Query: 770 FYIAELTLAIESVHKMGFIHRDIKPDNILIDLDGHIKLTDFGLCTGFRWTHNSKYY 825
Y ++ ++ + + F+HRD+ N ++D D H+K+ DFGL R + +YY
Sbjct: 309 MYGVDIARGMDYLAGLKFVHRDLAARNCMLDEDFHVKVADFGLA---RDIYEKEYY 151
>31489
Length = 329
Score = 37.7 bits (86), Expect = 0.023, Method: Composition-based stats.
Identities = 19/82 (23%), Positives = 42/82 (51%)
Frame = +3
Query: 717 RDILAEADNEWVVKLYYSFQDKDSLYFVMDYIPGGDMMSLLIRMEVFPEHLARFYIAELT 776
R+IL D+ Y+ F+D ++ +M+ D+ ++ + E R+++ ++
Sbjct: 48 REILKPKDS------YHDFKDIHVVFDLME----SDLHRIIYSDQPLTEEHIRYFLYQIL 197
Query: 777 LAIESVHKMGFIHRDIKPDNIL 798
++ +H +HRD+KP N+L
Sbjct: 198 RGLKYIHSANVVHRDLKPSNLL 263
>20640
Length = 1492
Score = 37.4 bits (85), Expect = 0.034, Method: Compositional matrix adjust.
Identities = 17/45 (37%), Positives = 26/45 (57%)
Frame = +1
Query: 786 GFIHRDIKPDNILIDLDGHIKLTDFGLCTGFRWTHNSKYYQKGSH 830
G++HRD+ N L+ D +K++DFGL R H+ YY+ H
Sbjct: 4 GYVHRDLATRNCLVGHDLVVKISDFGLA---RSVHSVDYYRGSEH 129
>07940
Length = 1336
Score = 37.0 bits (84), Expect = 0.038, Method: Compositional matrix adjust.
Identities = 41/178 (23%), Positives = 69/178 (38%), Gaps = 9/178 (5%)
Frame = -3
Query: 745 MDYIPGGDMMSL--------LIRMEVFPEHLARFYIAELTLAIESVHKMGFIHRDIKPDN 796
+ +IPG +S +++M + P+ L Y ++ +E + IHRD+ N
Sbjct: 428 LGFIPGTSTVSFSTGSHRQDMLKM-LTPKDLIS-YAYQVARGMEYLASKQCIHRDLAARN 255
Query: 797 ILIDLDGHIKLTDFGLCTGFRWTHNSKYYQKGSHVRQDSMEPSDLWDDVSNCRCGDRLKT 856
+L+ + +K+ DFGL R YY+K + D P
Sbjct: 254 VLVAEEYVLKIADFGLT---RNLQQFDYYRKTT----DGRLPV----------------- 147
Query: 857 LEQRARKQHQRCLAHSLVGTPNYIAPEVLLRKGYTQLCDWWSVGVILFEML-VGQPPF 913
++APE L + YT D WS GV+L+E+ +G P+
Sbjct: 146 ---------------------KWMAPEALFDRKYTSKSDVWSYGVLLWEIFTLGGNPY 36
>00392
Length = 668
Score = 37.0 bits (84), Expect = 0.047, Method: Compositional matrix adjust.
Identities = 42/216 (19%), Positives = 85/216 (39%), Gaps = 8/216 (3%)
Frame = +3
Query: 706 NRNQVAHVKAERDILAEADNEWVVKLY-----YSFQDKDSLYFVMDYIPGGDMMSLLIRM 760
N+ + K E ++L E + +V+ + ++ +++ + V + + G + + L R
Sbjct: 51 NKAERQRFKEEAEMLKELQHPNIVRFFDYWEEHNHRNRKVIILVTELMTSGTLKTYLKRF 230
Query: 761 EVFPEHLARFYIAELTLAIESVHKMG--FIHRDIKPDNILIDL-DGHIKLTDFGLCTGFR 817
+ + + + ++ + +H IHRD+K DNI I G +K+ D GL T
Sbjct: 231 KKPNVKILKNWCRQVLKGLYFLHTRTPPVIHRDLKCDNIFITGPTGSVKIGDLGLAT--- 401
Query: 818 WTHNSKYYQKGSHVRQDSMEPSDLWDDVSNCRCGDRLKTLEQRARKQHQRCLAHSLVGTP 877
LK + A S++GTP
Sbjct: 402 ------------------------------------LK----------NQSFAKSVIGTP 443
Query: 878 NYIAPEVLLRKGYTQLCDWWSVGVILFEMLVGQPPF 913
++APE + + Y + D ++ G+ + EM + P+
Sbjct: 444 EFMAPE-MYEEHYDEAVDVYAFGMCMLEMASSEYPY 548
>12672
Length = 773
Score = 36.6 bits (83), Expect = 0.062, Method: Composition-based stats.
Identities = 34/132 (25%), Positives = 50/132 (37%)
Frame = +3
Query: 778 AIESVHKMGFIHRDIKPDNILIDLDGHIKLTDFGLCTGFRWTHNSKYYQKGSHVRQDSME 837
I+ ++ G +HRDIK NIL+D + K+ DF
Sbjct: 27 GIQYLNDNGHVHRDIKTANILLDSEYTAKVGDFATVVS---------------------A 143
Query: 838 PSDLWDDVSNCRCGDRLKTLEQRARKQHQRCLAHSLVGTPNYIAPEVLLRKGYTQLCDWW 897
PS V N A ++GT Y+APE + T+L D +
Sbjct: 144 PSGEGKTVQN----------------------ASVVIGTAAYLAPEAIHFDVSTKL-DSY 254
Query: 898 SVGVILFEMLVG 909
S GV+L E++ G
Sbjct: 255 SFGVVLLEVITG 290
>23319
Length = 2235
Score = 35.8 bits (81), Expect = 0.095, Method: Compositional matrix adjust.
Identities = 38/128 (29%), Positives = 51/128 (39%), Gaps = 33/128 (25%)
Frame = +3
Query: 882 PEVLLRKGYTQLCDWWSVGVILFEML-VGQPPF--------------LAPTPTETQLKVI 926
P+V K Y+ D WS G I E+ G+P F L TPTE Q
Sbjct: 3 PDVYXAKMYSTSIDMWSAGCIFAELANAGRPLFPGNDDDDQLKRIFKLLGTPTEDQ---- 170
Query: 927 NWENTLHIP--------------AQV--KLSPEARDLITKL--CCSADHRLGRNGADDLK 968
W +P QV KL+ + RDL+ L CC +D R AD+
Sbjct: 171 -WPGMTQLPNYRMFPMYHVTTTWQQVVPKLNSKGRDLLQCLLVCCPSD----RMSADEAL 335
Query: 969 AHPFFSAI 976
HP+F+ +
Sbjct: 336 QHPYFADL 359
>11404
Length = 563
Score = 35.8 bits (81), Expect = 0.10, Method: Composition-based stats.
Identities = 37/133 (27%), Positives = 65/133 (48%), Gaps = 7/133 (5%)
Frame = +1
Query: 674 LGIGAFGEVCLACKVDTHALYAMKTLR-KKDVLNRNQVAHVKAERDILAEADNEW-VVKL 731
+G G+FG+V A + A+K ++ KK LN+ Q+ E + DN++ +V+L
Sbjct: 163 IGKGSFGQVVKAYDHTDNEQVAIKIIKNKKPFLNQAQIEVKLLEMMNRHDTDNKYYIVRL 342
Query: 732 YYSFQDKDSLYFVMDYIPGGDMMSLLIRMEVF---PEHLARFYIAELTLAIE--SVHKMG 786
F + L V + + + L+R F +L R + +L A+ + +M
Sbjct: 343 KRHFMFRSHLCLVFELLSYN--LYDLLRNTNFRGVSLNLTRKFAQQLCTALLFLATPEMS 516
Query: 787 FIHRDIKPDNILI 799
IH D+KP+NIL+
Sbjct: 517 IIHCDLKPENILL 555
>09007
Length = 1440
Score = 35.4 bits (80), Expect = 0.12, Method: Compositional matrix adjust.
Identities = 55/249 (22%), Positives = 92/249 (36%), Gaps = 13/249 (5%)
Frame = -1
Query: 672 KTLGIGAFGEV---CLACKVDTHALYAMKTLRKKDVLNRNQVAHVKAERDILAEADNEWV 728
K+LG G FG V + A+K L KD ++++ +K E I+ D+E +
Sbjct: 861 KSLGQGHFGTVRQAIWTAESGEKVQVAVKCL-SKDKIHKDGQEFLK-ETAIMQMLDHENI 688
Query: 729 VKLYYSFQDKDS-LYFVMDYIPGGDMMSLLIRMEVFPEHLARF---------YIAELTLA 778
V++Y D + + V + P M SLL E E AR + ++
Sbjct: 687 VRVYGVVMDNGADIMLVTELAP---MRSLL---ECVKEVSARVDFSVPRLCDFSQQVCDG 526
Query: 779 IESVHKMGFIHRDIKPDNILIDLDGHIKLTDFGLCTGFRWTHNSKYYQKGSHVRQDSMEP 838
+ + +HRD+ NIL+ +K++D G+ +YYQ S +
Sbjct: 525 MSYLESKRLVHRDLAARNILLFSKSKVKISDVGVSGAL--GAGKEYYQ--------SQQT 376
Query: 839 SDLWDDVSNCRCGDRLKTLEQRARKQHQRCLAHSLVGTPNYIAPEVLLRKGYTQLCDWWS 898
L + V+ C APE ++ D W+
Sbjct: 375 IHLQNAVAWC--------------------------------APESFRNLCFSSASDVWA 292
Query: 899 VGVILFEML 907
GV+L+E
Sbjct: 291 FGVLLWEFF 265
>17591
Length = 474
Score = 27.3 bits (59), Expect(2) = 0.13, Method: Composition-based stats.
Identities = 16/50 (32%), Positives = 28/50 (56%), Gaps = 2/50 (4%)
Frame = +2
Query: 904 FEMLVGQPPFLAPTPTETQLKVINWENTLHIPAQVK--LSPEARDLITKL 951
FEML G PPF + +E +EN L+ P +++ +S R+++ +L
Sbjct: 2 FEMLYGLPPFYSRDTSEM------YENILYKPLRLRTNVSAAGRNILEEL 133
Score = 26.9 bits (58), Expect(2) = 0.13, Method: Compositional matrix adjust.
Identities = 17/52 (32%), Positives = 29/52 (55%), Gaps = 3/52 (5%)
Frame = +3
Query: 956 DHRLG-RNGADDLKAHPFFSAIDFSSDIRK--QPAPYVPTISHPMDTSNFDP 1004
+ RLG + ++++ FF+ I++ K QP PY P +S +D +FDP
Sbjct: 150 EERLGAKRDFEEIQEKAFFADINWDDLYNKKVQP-PYNPNVSGQLDLRHFDP 302
>21800
Length = 855
Score = 35.4 bits (80), Expect = 0.14, Method: Composition-based stats.
Identities = 20/56 (35%), Positives = 32/56 (57%), Gaps = 3/56 (5%)
Frame = +2
Query: 750 GGDMMSLLIR--MEVFPEHLARFYIAELTLAIESVH-KMGFIHRDIKPDNILIDLD 802
G +++ L+IR + P H + I ++ + +H K IH DIKP+NILI +D
Sbjct: 578 GYNLLKLIIRSNYQGIPVHNVKLIIRQVLEGLNYLHAKCNIIHTDIKPENILICVD 745
>26009
Length = 886
Score = 35.4 bits (80), Expect = 0.14, Method: Compositional matrix adjust.
Identities = 13/32 (40%), Positives = 22/32 (68%)
Frame = +3
Query: 768 ARFYIAELTLAIESVHKMGFIHRDIKPDNILI 799
A+ + +L A++ +H +HRDIKP+N+LI
Sbjct: 717 AKSVMKQLVSALDFMHSKQLVHRDIKPENVLI 812
>11780
Length = 1713
Score = 35.0 bits (79), Expect = 0.16, Method: Compositional matrix adjust.
Identities = 33/148 (22%), Positives = 70/148 (47%), Gaps = 7/148 (4%)
Frame = +3
Query: 672 KTLGIGAFGEVCLACKVDTHALY-----AMKTLRKKDVLNRNQVAHVKAERDILAEADNE 726
+ +G G FG+V +Y A+K L+ KD R + + ++ E ++ ++
Sbjct: 615 EAIGKGDFGDV-------YKGMYRGQPVAIKQLKDKD---RGEQSFLQ-EASVMTSLRHD 761
Query: 727 WVVKLYYSFQDKDSLYFVMDYIPGGDMMSLLIRM--EVFPEHLARFYIAELTLAIESVHK 784
+V+L ++++ V +++ G+++ L V + + + A+E +
Sbjct: 762 NLVRLI-GVVLGETIFLVTEFMGKGNLVEYLRSRGRSVITKKDQINFATDTCAAMEYLES 938
Query: 785 MGFIHRDIKPDNILIDLDGHIKLTDFGL 812
+HRD+ N+L+ DG K++DFGL
Sbjct: 939 KRLVHRDLAARNVLVHDDGKAKVSDFGL 1022
>17300
Length = 480
Score = 34.3 bits (77), Expect = 0.25, Method: Composition-based stats.
Identities = 30/131 (22%), Positives = 46/131 (35%), Gaps = 2/131 (1%)
Frame = +1
Query: 785 MGFIHRDIKPDNILIDLDGHIKLTDFGLCTGFRW-THNSKYYQKGSHVRQDSMEPSDLWD 843
MG++HRD+ NIL++ K+ DFGL T Y KG +
Sbjct: 31 MGYVHRDLAARNILVNEILVCKVADFGLSREIESDTTEGAYTTKGGKI------------ 174
Query: 844 DVSNCRCGDRLKTLEQRARKQHQRCLAHSLVGTPNYIAPEVLLRKGYTQLCDWWSVGVIL 903
+ APE + + +T D WS GV++
Sbjct: 175 --------------------------------PVRWTAPEAIAYRKFTSASDVWSFGVVM 258
Query: 904 FE-MLVGQPPF 913
+E M G+ P+
Sbjct: 259 WEVMSYGERPY 291
>29360
Length = 363
Score = 33.9 bits (76), Expect = 0.39, Method: Composition-based stats.
Identities = 28/120 (23%), Positives = 53/120 (44%), Gaps = 3/120 (2%)
Frame = +3
Query: 683 CLACKVDTHALYAMKTLRKKDVLNRNQVAHVKAERDILAE-ADNEWVVKLYYSFQDKDSL 741
C K T + A+K L+ R V + + E AD+ V+ + FQ K+
Sbjct: 3 CKCWKKGTSEIVAIKILKNHPSYARQGQIEVSILQRLSQESADDYNFVRAFECFQHKNHT 182
Query: 742 YFVMDYIPGGDMMSLLI--RMEVFPEHLARFYIAELTLAIESVHKMGFIHRDIKPDNILI 799
V + + ++ L + + P R ++ A+ + ++G IH D+KP+NI++
Sbjct: 183 CLVFEMLEQ-NLYDFLKQNKFQPLPLKYIRPITQQVLTALRKLKQLGLIHADLKPENIML 359
>18996
Length = 491
Score = 33.9 bits (76), Expect = 0.39, Method: Compositional matrix adjust.
Identities = 35/141 (24%), Positives = 51/141 (36%), Gaps = 1/141 (0%)
Frame = +2
Query: 788 IHRDIKPDNILIDLDGHIKLTDFGLCTGFRWTHNSKYYQKGSHVRQDSMEPSDLWDDVSN 847
IHRD+ NIL+D +K++DFGL N+ Y G R ++
Sbjct: 2 IHRDLAARNILVDRSC-VKISDFGLAQ----FANADGYYYGISQRDIPIK---------- 136
Query: 848 CRCGDRLKTLEQRARKQHQRCLAHSLVGTPNYIAPEVLLRKGYTQLCDWWSVGVILFEML 907
+ +PE + ++ D WS GV LFEM
Sbjct: 137 -------------------------------WYSPEAIETCKFSSYSDVWSYGVTLFEMF 223
Query: 908 V-GQPPFLAPTPTETQLKVIN 927
G+ P L P TQ + +N
Sbjct: 224 SRGEIPNLLPGHDLTQEEFLN 286
>13078
Length = 773
Score = 33.5 bits (75), Expect = 0.47, Method: Compositional matrix adjust.
Identities = 12/25 (48%), Positives = 17/25 (68%)
Frame = -1
Query: 889 GYTQLCDWWSVGVILFEMLVGQPPF 913
G++Q CD WS+G I+FE+ G F
Sbjct: 749 GWSQPCDVWSIGCIMFELYTGYTLF 675
>22153
Length = 353
Score = 33.1 bits (74), Expect = 0.60, Method: Compositional matrix adjust.
Identities = 18/44 (40%), Positives = 24/44 (54%)
Frame = +3
Query: 889 GYTQLCDWWSVGVILFEMLVGQPPFLAPTPTETQLKVINWENTL 932
G Q C + GV+L E VG P L P + T ++V+N E TL
Sbjct: 114 GAPQDCARSAPGVVLLEAAVGIPLSLPPPHSHTPIQVVNTEATL 245
>07836
Length = 1478
Score = 32.3 bits (72), Expect = 1.1, Method: Compositional matrix adjust.
Identities = 26/79 (32%), Positives = 35/79 (44%), Gaps = 7/79 (8%)
Frame = -1
Query: 741 LYFVMDYIPGGDMMS-LLIRMEVFPEHLARFYIAELTLAIESVHKMG------FIHRDIK 793
L+ + DY G + LL R+ E LA + A LA + G HRDIK
Sbjct: 1328 LFLITDYHENGSLHDYLLSRVLDSSEMLALAHSAICGLAHLHIEIFGTRGKPAIAHRDIK 1149
Query: 794 PDNILIDLDGHIKLTDFGL 812
NIL+ +G + D GL
Sbjct: 1148 SKNILVKKNGTCCIADLGL 1092
>37063
Length = 455
Score = 32.0 bits (71), Expect = 1.5, Method: Composition-based stats.
Identities = 15/35 (42%), Positives = 21/35 (60%), Gaps = 5/35 (14%)
Frame = -2
Query: 874 VGTPNYIAPEVL-----LRKGYTQLCDWWSVGVIL 903
VG+ Y+APEV+ Y + CD WS+G+IL
Sbjct: 325 VGSAEYMAPEVVDAWVGESFSYDKRCDMWSLGIIL 221
>26058
Length = 431
Score = 32.0 bits (71), Expect = 1.6, Method: Compositional matrix adjust.
Identities = 12/35 (34%), Positives = 21/35 (60%), Gaps = 1/35 (2%)
Frame = -3
Query: 873 LVGTPNYIAPEVLLRKGYTQLCD-WWSVGVILFEM 906
+ TP + +P +LLR ++ LCD W+SV + +
Sbjct: 132 VAATPTHSSPAILLRNAWSLLCDIWYSVHPVCLQC 28
>31120
Length = 439
Score = 31.6 bits (70), Expect = 1.8, Method: Composition-based stats.
Identities = 13/22 (59%), Positives = 17/22 (77%)
Frame = +1
Query: 892 QLCDWWSVGVILFEMLVGQPPF 913
++ D WS+GVILF ML G+ PF
Sbjct: 31 KMADAWSLGVILFIMLNGKMPF 96
>17637
Length = 447
Score = 31.2 bits (69), Expect = 2.7, Method: Compositional matrix adjust.
Identities = 21/83 (25%), Positives = 36/83 (43%), Gaps = 7/83 (8%)
Frame = +1
Query: 847 NCRCGDRLKT------LEQRARKQHQRCLAHSLVGTPNYIAPEVLLRKGYTQLCDWWSVG 900
NC D+L+ L + CL +++ E L + Y + D WS G
Sbjct: 1 NCVIDDQLRVKLTDSALSRDLFSGDYNCLGDGEYRPIKWLSLEALQKSHYNEGSDVWSFG 180
Query: 901 VILFEML-VGQPPFLAPTPTETQ 922
V+++EM +G+ P+ P E +
Sbjct: 181 VLMWEMCTLGKLPYAEIDPYEME 249
>13305
Length = 549
Score = 30.8 bits (68), Expect = 3.3, Method: Composition-based stats.
Identities = 17/45 (37%), Positives = 26/45 (57%), Gaps = 1/45 (2%)
Frame = +2
Query: 879 YIAPEVLLRKGYTQLCDWWSVGVILFEML-VGQPPFLAPTPTETQ 922
++A E L YT D WS GV+L+E+ +G P+ + T+TQ
Sbjct: 23 WMAVESLFNNTYTTQSDVWSFGVVLWEIFTLGGTPY---SSTDTQ 148
>22098
Length = 1090
Score = 30.4 bits (67), Expect = 4.4, Method: Compositional matrix adjust.
Identities = 16/43 (37%), Positives = 27/43 (62%), Gaps = 6/43 (13%)
Frame = +2
Query: 871 HSLVGTPNYIAPEVLL------RKGYTQLCDWWSVGVILFEML 907
H LVGT Y+APEVL R + ++ D ++ G++L+E++
Sbjct: 8 HGLVGTRRYMAPEVLEGAICFNRDSFLRI-DMYACGLVLWELM 133
>02124
Length = 2705
Score = 29.6 bits (65), Expect = 7.1, Method: Compositional matrix adjust.
Identities = 15/32 (46%), Positives = 18/32 (56%)
Frame = -1
Query: 917 TPTETQLKVINWENTLHIPAQVKLSPEARDLI 948
TPT T L + + N HIP+QV L E D I
Sbjct: 1406 TPTHTNLYICIYHNYSHIPSQVILVVERGDSI 1311
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000375668 | hsapiens_gene_ensembl |
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A
alpha isoform (PP2A, subunit A, PR65-alpha isoform) (PP2A, subunit A,
R1-alpha isoform) (Medium tumor antigen-associated 61 kDa protein).
[Source:Uniprot/SWISSPROT;Acc:P30153]
(509 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
26856 712 0.0
01469 47 2e-05
25614 41 0.001
28518 32 0.54
30928 32 0.77
14913 31 1.4
09672 28 8.3
28579 28 9.9
>26856
Length = 2013
Score = 712 bits (1838), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 344/452 (76%), Positives = 398/452 (88%)
Frame = +1
Query: 58 WWEAQSTCTACCLFSVCYPRVSSAVKAELRQYFRNLCSDDTPMVRRAAASKLGEFAKVLE 117
W+ ++++ AC LF+ CY RV+S+VKA+LRQ FRNLCSDDTPMVRRAAA KLGEFAK +E
Sbjct: 214 WFTSRTS--ACGLFACCYARVASSVKADLRQLFRNLCSDDTPMVRRAAAGKLGEFAKEVE 387
Query: 118 LDNVKSEIIPMFSNLASDEQDSVRLLAVEACVNIAQLLPQEDLEALVMPTLRQAAEDKSW 177
+ +KS++IP+F+ LA DEQDSVRLLAVEACV+IA LLP ED E LVMPTLRQA+EDKSW
Sbjct: 388 SEFLKSDLIPLFAMLAQDEQDSVRLLAVEACVSIASLLPSEDTEQLVMPTLRQASEDKSW 567
Query: 178 RVRYMVADKFTELQKAVGPEITKTDLVPAFQNLMKDCEAEVRAAASHKVKEFCENLSADC 237
RVRYMVADKFTELQKAVGPEITK DLVPAFQ+L+KDCEAEVRAA+++KVK+FC+ LS D
Sbjct: 568 RVRYMVADKFTELQKAVGPEITKNDLVPAFQSLLKDCEAEVRAASANKVKDFCQALSPDV 747
Query: 238 RENVIMSQILPCIKELVSDANQHVKSALASVIMGLSPILGKDNTIEHLLPLFLAQLKDEC 297
RE +IM+ ILPC+K+LV+DANQHVKSALASVIMGLSPILGKDNTIEHLLPLFL+QLKDEC
Sbjct: 748 RETIIMTNILPCVKDLVADANQHVKSALASVIMGLSPILGKDNTIEHLLPLFLSQLKDEC 927
Query: 298 PEVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAGQLGVE 357
P+VRLNIISNLDCVNEVIGI+QLSQSLLPAIVELAED KWRVRLAIIEYMPLLAGQLGV+
Sbjct: 928 PDVRLNIISNLDCVNEVIGIKQLSQSLLPAIVELAEDTKWRVRLAIIEYMPLLAGQLGVQ 1107
Query: 358 FFDEKLNSLCMAWLVDHVYAIREAATSNLKKLVEKFGKEWAHATIIPKVLAMSGDPNYLH 417
FFDEKLNSLCM WLVDHV+AIREAAT NLKKLVEKFG EWA T+IPKV +MS D NYLH
Sbjct: 1108FFDEKLNSLCMTWLVDHVFAIREAATLNLKKLVEKFGPEWAQETVIPKVTSMSKDSNYLH 1287
Query: 418 RMTTLFCINVLSEVCGQDITTKHMLPTVLRMAGDPVANVRFNVAKSLQKIGPILDNSTLQ 477
RMT LF IN+L+E GQ++T+K +LPT +A D V NVRFN AK+LQKI P+LD ST+Q
Sbjct: 1288RMTCLFSINLLAETMGQELTSKLLLPTRF-LARDTVPNVRFNAAKTLQKIAPLLDQSTVQ 1464
Query: 478 SEVKPILEKLTQDQDVDVKYFAQEALTVLSLA 509
S+VKPILE L D D+DV++FA +AL V+ +
Sbjct: 1465SQVKPILETLKSDSDIDVQFFAADALDVIGVG 1560
Score = 76.3 bits (186), Expect = 3e-14, Method: Compositional matrix adjust.
Identities = 84/366 (22%), Positives = 142/366 (38%), Gaps = 4/366 (1%)
Frame = +1
Query: 129 FSNLASDEQDSVRLLAVEACVNIAQLLPQEDLEALVMPTLRQAAEDKSWRVRYMVADKFT 188
+LA+ E+ VR AV++ NIA DLEA +P +++ + + R F
Sbjct: 73 LESLATVEETVVRDKAVDSLRNIAAQHSXSDLEAHFVPLVKRLSTGDWFTSRTSACGLFA 252
Query: 189 ELQKAVGPEITKTDLVPAFQNLMKDCEAEVRAAASHKVKEFCENLSADCRENVIMSQILP 248
V + K DL F+NL D VR AA+ K+ EF + + +
Sbjct: 253 CCYARVASSV-KADLRQLFRNLCSDDTPMVRRAAAGKLGEFAKEVES------------- 390
Query: 249 CIKELVSDANQHVKSALASVIMGLSPILGKDNTIEHLLPLFLAQLKDECPEVRLNIISNL 308
+ +KS L +PLF +DE VRL +
Sbjct: 391 ----------EFLKSDL--------------------IPLFAMLAQDEQDSVRLLAVEAC 480
Query: 309 DCVNEVIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAGQLGVEFFDEKLNSLCM 368
+ ++ Q ++P + + +ED WRVR + + L +G E L
Sbjct: 481 VSIASLLPSEDTEQLVMPTLRQASEDKSWRVRYMVADKFTELQKAVGPEITKNDLVPAFQ 660
Query: 369 AWLVDHVYAIREAATSNLKKLVEKFGKEWAH----ATIIPKVLAMSGDPNYLHRMTTLFC 424
+ L D +R A+ + +K + + I+P V + D N +
Sbjct: 661 SLLKDCEAEVRAASANKVKDFCQALSPDVRETIIMTNILPCVKDLVADANQHVKSALASV 840
Query: 425 INVLSEVCGQDITTKHMLPTVLRMAGDPVANVRFNVAKSLQKIGPILDNSTLQSEVKPIL 484
I LS + G+D T +H+LP L D +VR N+ +L + ++ L + P +
Sbjct: 841 IMGLSPILGKDNTIEHLLPLFLSQLKDECPDVRLNIISNLDCVNEVIGIKQLSQSLLPAI 1020
Query: 485 EKLTQD 490
+L +D
Sbjct: 1021VELAED 1038
>01469
Length = 2023
Score = 46.6 bits (109), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 37/138 (26%), Positives = 61/138 (44%), Gaps = 3/138 (2%)
Frame = +1
Query: 167 TLRQAAEDKSWRVRYMVADKFTELQKAVGPEITKTDLVPAFQNLMKDCEAEVRAAASHKV 226
TL QA + W+VR +A E+ G IT DL+P F +KD + EVR +
Sbjct: 454 TLAQAMQ---WKVRRTLAFSIHEMALIEGEAITHNDLLPVFDGFIKDLD-EVRIGVLKHL 621
Query: 227 KEFCENLSADCRENVIMSQILPCIKELVSDANQ---HVKSALASVIMGLSPILGKDNTIE 283
+F L + R+ Q L + + + N + L+ ++ L + + +
Sbjct: 622 ADFLRLLRPNVRQ-----QYLAKVSDFMKTDNHRNWRFRKELSEQLIYLCELFDPRSIVR 786
Query: 284 HLLPLFLAQLKDECPEVR 301
H+ PL +A D+ EVR
Sbjct: 787 HICPLAVALCMDKVAEVR 840
Score = 37.4 bits (85), Expect = 0.014, Method: Compositional matrix adjust.
Identities = 67/276 (24%), Positives = 123/276 (44%), Gaps = 23/276 (8%)
Frame = +1
Query: 249 CIKELVSDANQ----HVKSALASVIMGLSPILGKDNTIEHLLPLFLAQLKDECPEVRLNI 304
CIK L Q V+ LA I ++ I G+ T LLP+F +KD EVR+ +
Sbjct: 433 CIKHLYETLAQAMQWKVRRTLAFSIHEMALIEGEAITHNDLLPVFDGFIKD-LDEVRIGV 609
Query: 305 ISNLDCVNEVI--GIRQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAGQLGVEFFDEK 362
+ +L ++ +RQ + + ++ WR R + E + L E FD +
Sbjct: 610 LKHLADFLRLLRPNVRQQYLAKVSDFMKTDNHRNWRFRKELSEQLIYLC-----ELFDPR 774
Query: 363 --LNSLC---MAWLVDHVYAIREAATSNLKKLVEKFGKEWAHATIIPKVLAMSGDPNYLH 417
+ +C +A +D V +R A + L V + E ++ + + D L+
Sbjct: 775 SIVRHICPLAVALCMDKVAEVR-AVSFGLMSAVLRRVHEEGEDKLLQVICSDLSDQFALN 951
Query: 418 ------RMTTLFCINVLSE-VCGQDITTKHMLPTVLRMAGDPVANVRFNVAKSL-QKIGP 469
++ C+ VL++ + + +LP +L + D + NVR +AK L Q++ P
Sbjct: 952 IKWLGRQIYCQMCLVVLADNAVPPPVFAELLLPGLLALGTDAIPNVRLTLAKVLAQRVAP 1131
Query: 470 ILDNSTLQS----EVKPILEKLTQDQDVDVKYFAQE 501
+ ++ Q+ + L+ L D+D DV+YF+ +
Sbjct: 1132LDYFTSSQNPCHEALLTTLQALKTDKDQDVRYFSSQ 1239
>25614
Length = 433
Score = 40.8 bits (94), Expect = 0.001, Method: Composition-based stats.
Identities = 35/116 (30%), Positives = 48/116 (41%)
Frame = -2
Query: 285 LLPLFLAQLKDECPEVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVRLAII 344
LLP F L D VR +N V V+G + + LLP + L ED W VR A
Sbjct: 408 LLPRFSQMLTDPLFHVRKVCAANFGEVCSVVGKQSSEELLLPKLNSLCEDGVWGVRKACA 229
Query: 345 EYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATSNLKKLVEKFGKEWAHA 400
E ++ +E L L + L D +R +A +L + F AHA
Sbjct: 228 ECFMAISCACSLETRRGYLARLFVHLLADQSRWVRMSAFQHLGPFISTF----AHA 73
Score = 30.8 bits (68), Expect = 1.5, Method: Composition-based stats.
Identities = 19/101 (18%), Positives = 44/101 (43%)
Frame = -2
Query: 371 LVDHVYAIREAATSNLKKLVEKFGKEWAHATIIPKVLAMSGDPNYLHRMTTLFCINVLSE 430
L D ++ +R+ +N ++ GK+ + ++PK+ ++ D + R C +S
Sbjct: 384 LTDPLFHVRKVCAANFGEVCSVVGKQSSEELLLPKLNSLCEDGVWGVRKACAECFMAISC 205
Query: 431 VCGQDITTKHMLPTVLRMAGDPVANVRFNVAKSLQKIGPIL 471
C + ++ + + D VR + + Q +GP +
Sbjct: 204 ACSLETRRGYLARLFVHLLADQSRWVRMS---AFQHLGPFI 91
>28518
Length = 1528
Score = 32.0 bits (71), Expect = 0.54, Method: Compositional matrix adjust.
Identities = 12/20 (60%), Positives = 17/20 (85%)
Frame = +2
Query: 31 CLSLQIPSMMKMRSSWPWQN 50
CLS+ +PS+ KMRS +P+QN
Sbjct: 413 CLSVGVPSLKKMRSLYPFQN 472
>30928
Length = 343
Score = 31.6 bits (70), Expect = 0.77, Method: Composition-based stats.
Identities = 18/57 (31%), Positives = 28/57 (49%)
Frame = +2
Query: 125 IIPMFSNLASDEQDSVRLLAVEACVNIAQLLPQEDLEALVMPTLRQAAEDKSWRVRY 181
I+P +DE + VR A+ A I +E L++P L + D +WR+RY
Sbjct: 89 ILPSILQALADESEFVRDTALRAGQRIISQYADTAIE-LLLPELERGLFDDNWRIRY 256
>14913
Length = 1174
Score = 30.8 bits (68), Expect = 1.4, Method: Compositional matrix adjust.
Identities = 16/37 (43%), Positives = 24/37 (64%), Gaps = 2/37 (5%)
Frame = -3
Query: 95 SDDTPMVRRAAASKLGEFAKVLELDNVK--SEIIPMF 129
+D PMVR AA LG+F++ L+ D K SE++P+
Sbjct: 119 NDSEPMVRNAALFALGQFSEHLQPDITKFASELLPLL 9
>09672
Length = 1963
Score = 28.1 bits (61), Expect = 8.3, Method: Compositional matrix adjust.
Identities = 22/78 (28%), Positives = 36/78 (46%), Gaps = 6/78 (7%)
Frame = -2
Query: 230 CENLSADCRENVIMSQILPCIKELVSDANQHVKSALASVIMGLSPIL-GKDN-----TIE 283
C L A C E+ ++ +LP +KE + A+ + A +M IL G D+ +E
Sbjct: 1959 CLMLMATCCEDDVVPHVLPFVKENIRHADWRYRDA---AVMAFGSILEGPDSEKLKPIVE 1789
Query: 284 HLLPLFLAQLKDECPEVR 301
+P+ + L D VR
Sbjct: 1788 QAMPMLIELLTDPSVVVR 1735
>28579
Length = 471
Score = 28.1 bits (61), Expect = 9.9, Method: Composition-based stats.
Identities = 20/50 (40%), Positives = 28/50 (56%), Gaps = 1/50 (2%)
Frame = +3
Query: 389 LVEKFGKEWAHATIIPKV-LAMSGDPNYLHRMTTLFCINVLSEVCGQDIT 437
LVE G + AT+IP + LA S N+LH +T L ++CGQD +
Sbjct: 48 LVEIIGLD---ATLIPSLPLATS---NFLHAITFLLTFTETIDLCGQDTS 179
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000375938 | hsapiens_gene_ensembl | Tubulin
alpha-4A chain (Tubulin alpha-1 chain) (Alpha-tubulin 1)
(Testis-specific alpha-tubulin) (Tubulin H2-alpha).
[Source:Uniprot/SWISSPROT;Acc:P68366]
(433 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
00276 687 0.0
12457 449 e-131
06360 300 9e-82
03702 278 3e-75
17215 253 7e-68
16482 198 4e-51
13181 188 5e-48
04882 176 2e-44
05902 137 7e-33
25015 114 1e-25
28905 91 8e-19
31457 88 6e-18
39157 77 1e-14
13964 33 0.15
26569 32 0.50
06591 30 2.7
18555 28 6.0
>00276
Length = 1330
Score = 687 bits (1774), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 328/360 (91%), Positives = 338/360 (93%)
Frame = -3
Query: 65 NGPYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDPVLDRIRKLSDQCTGLQGFLVFH 124
G YRQL PEQL+TGKEDAANNYARGHYTIGKE++D VLDRIRKL+DQCTGLQGFL+FH
Sbjct: 1328 TGTYRQL-SPEQLVTGKEDAANNYARGHYTIGKELVDLVLDRIRKLADQCTGLQGFLIFH 1152
Query: 125 XXXXXXXXXXXXLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSD 184
L MERLSVDYGKKSKLEF IYPAPQVSTAVVEPYNSILTTHTTLEHSD
Sbjct: 1151 SFGGGTGSGFTSLXMERLSVDYGKKSKLEFXIYPAPQVSTAVVEPYNSILTTHTTLEHSD 972
Query: 185 CAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNL 244
CAFMVDNEAIYDICRRNLDIERPTYTNLNRLI QIVSSITASLRFDGALNVDLTEFQTNL
Sbjct: 971 CAFMVDNEAIYDICRRNLDIERPTYTNLNRLIXQIVSSITASLRFDGALNVDLTEFQTNL 792
Query: 245 VPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLY 304
VPYPRIHFPLATYAPVISAEKAYHEQL VAEITNACFEPANQ+VKCDPRHGKYMACC+LY
Sbjct: 791 VPYPRIHFPLATYAPVISAEKAYHEQLXVAEITNACFEPANQLVKCDPRHGKYMACCMLY 612
Query: 305 RGDVVPKDVNAAIAAIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLS 364
RGDVVPKDVNAAIA IKTKR+IQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLS
Sbjct: 611 RGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLS 432
Query: 365 NTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGIDS 424
NTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEARED+AALEKDYEEVG+DS
Sbjct: 431 NTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGVDS 252
>12457
Length = 781
Score = 449 bits (1154), Expect(2) = e-131, Method: Compositional matrix adjust.
Identities = 214/239 (89%), Positives = 222/239 (92%)
Frame = -1
Query: 52 FVDLEPTVIDEIRNGPYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDPVLDRIRKLS 111
VDLEPTV+DE+R G YRQLFHPEQL+TGKEDAANNYARGHYTIGKEI+D VLDRIRKL+
Sbjct: 718 LVDLEPTVVDEVRTGTYRQLFHPEQLVTGKEDAANNYARGHYTIGKEIVDLVLDRIRKLA 539
Query: 112 DQCTGLQGFLVFHXXXXXXXXXXXXLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYN 171
DQCTGLQGFL+FH LLMERLSVDYGKKSKLEF+IYPAPQVSTAVVEPYN
Sbjct: 538 DQCTGLQGFLIFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFAIYPAPQVSTAVVEPYN 359
Query: 172 SILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDG 231
SILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLI QIVSSITASLRFDG
Sbjct: 358 SILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDG 179
Query: 232 ALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKC 290
ALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQL+VAEITNACFEPANQMVKC
Sbjct: 178 ALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLTVAEITNACFEPANQMVKC 2
Score = 37.4 bits (85), Expect(2) = e-131, Method: Compositional matrix adjust.
Identities = 19/28 (67%), Positives = 19/28 (67%)
Frame = -2
Query: 30 GDDSFTTFFCETGAGKHVPRAVFVDLEP 57
GDDSFT ETGAGKHVPRAV P
Sbjct: 780 GDDSFTPL-SETGAGKHVPRAVSSXXSP 700
>06360
Length = 1896
Score = 300 bits (767), Expect = 9e-82, Method: Compositional matrix adjust.
Identities = 139/163 (85%), Positives = 146/163 (89%)
Frame = -1
Query: 1 MGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFTTFFCETGAGKHVPRAVFVDLEPTVI 60
MGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSF TFF ETGAGKHVPRAVFVDLEPTV+
Sbjct: 1665 MGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVV 1486
Query: 61 DEIRNGPYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDPVLDRIRKLSDQCTGLQGF 120
DE+R G YRQLFHPEQL+TGKEDAANNYARGHYTIGKEI+D VLDRIRKL+DQCTGLQGF
Sbjct: 1485 DEVRTGTYRQLFHPEQLVTGKEDAANNYARGHYTIGKEIVDLVLDRIRKLADQCTGLQGF 1306
Query: 121 LVFHXXXXXXXXXXXXLLMERLSVDYGKKSKLEFSIYPAPQVS 163
L+FH LLMERLSVDYGKKSKLEF+IYPAPQVS
Sbjct: 1305 LIFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFAIYPAPQVS 1177
>03702
Length = 1932
Score = 278 bits (711), Expect = 3e-75, Method: Compositional matrix adjust.
Identities = 138/155 (89%), Positives = 142/155 (91%)
Frame = +1
Query: 138 LMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDI 197
L ERLSVDYGKKSKLEF+IYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDI
Sbjct: 1453 L*ERLSVDYGKKSKLEFAIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDI 1632
Query: 198 CRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATY 257
CRRNLDIERP YTNLNRLI QIVSSITASLRFDGALNVDLTEFQTNLVP P P
Sbjct: 1633 CRRNLDIERPXYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVPTPH-PLPPGHL 1809
Query: 258 APVISAEKAYHEQLSVAEITNACFEPANQMVKCDP 292
PVISAEKAYHEQL+VAE+TNACFEPANQ+VKCDP
Sbjct: 1810 CPVISAEKAYHEQLTVAEVTNACFEPANQLVKCDP 1914
>17215
Length = 632
Score = 253 bits (647), Expect = 7e-68, Method: Compositional matrix adjust.
Identities = 118/123 (95%), Positives = 122/123 (99%)
Frame = +3
Query: 302 LLYRGDVVPKDVNAAIAAIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVC 361
+LYRGDVVPKDVNAAIA IKTKR+IQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVC
Sbjct: 3 MLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVC 182
Query: 362 MLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVG 421
MLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEARED+AALEKDYEEVG
Sbjct: 183 MLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVG 362
Query: 422 IDS 424
+DS
Sbjct: 363 VDS 371
>16482
Length = 837
Score = 198 bits (503), Expect = 4e-51, Method: Compositional matrix adjust.
Identities = 96/233 (41%), Positives = 140/233 (60%)
Frame = +1
Query: 1 MGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFTTFFCETGAGKHVPRAVFVDLEPTVI 60
+G WE+ EHGI P G D + + ++ E GK+VPRAV VDLEP +
Sbjct: 145 IGAKFWEVISDEHGIDPTGTYHGDSDLQ--LERINVYYNEATGGKYVPRAVLVDLEPGTM 318
Query: 61 DEIRNGPYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDPVLDRIRKLSDQCTGLQGF 120
D +R+GP+ Q+F P+ + G+ A NN+A+GHYT G E++D VLD +RK ++ C LQGF
Sbjct: 319 DSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGF 498
Query: 121 LVFHXXXXXXXXXXXXLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTL 180
+ H LL+ ++ +Y + FS+ P+P+VS VVEPYN+ L+ H +
Sbjct: 499 QLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLV 678
Query: 181 EHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGAL 233
E++D + +DNEA+YDIC R L + PTY +LN L+S +S +T LRF G L
Sbjct: 679 ENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQL 837
>13181
Length = 1092
Score = 188 bits (477), Expect = 5e-48, Method: Compositional matrix adjust.
Identities = 85/225 (37%), Positives = 131/225 (58%)
Frame = -3
Query: 195 YDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPL 254
YDIC R L + PTY +LN L+S +S +T LRF G LN DL + N+VP+PR+HF +
Sbjct: 1090 YDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFM 911
Query: 255 ATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVN 314
+AP+ S + L+V E+T F+ N M CDPRHG+Y+ ++RG + K+V+
Sbjct: 910 PGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAMFRGRMSMKEVD 731
Query: 315 AAIAAIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWA 374
+ ++ K S FV+W P K + PP ++ + + N+TAI E +
Sbjct: 730 EQMLNVQNKNSSYFVEWIPNNVKTAVCDIPP--------RGLKMSATFVGNSTAIQELFK 575
Query: 375 RLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEE 419
R+ +F M+ ++AF+HWY GEGM+E EF+EA +M L +Y++
Sbjct: 574 RISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQ 440
>04882
Length = 1136
Score = 176 bits (446), Expect = 2e-44, Method: Compositional matrix adjust.
Identities = 79/216 (36%), Positives = 125/216 (57%)
Frame = +2
Query: 204 IERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISA 263
+ PTY +LN L+S +S +T LRF G LN DL + N+VP+PR+HF + +AP+ S
Sbjct: 314 VHTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSR 493
Query: 264 EKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIAAIKTK 323
+ L+V E+T F+ N M CDPRHG+Y+ ++RG + K+V+ + ++ K
Sbjct: 494 GSQQYRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNK 673
Query: 324 RSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLM 383
S FV+W P K + PP ++ + + N+TAI E + R+ +F M
Sbjct: 674 NSSYFVEWIPNNVKTAVCDIPPR--------GLKMSATFIGNSTAIQELFKRISEQFTAM 829
Query: 384 YAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEE 419
+ ++AF+HWY GEGM+E EF+EA +M L +Y++
Sbjct: 830 FRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQ 937
>05902
Length = 1127
Score = 137 bits (346), Expect = 7e-33, Method: Compositional matrix adjust.
Identities = 82/290 (28%), Positives = 160/290 (55%), Gaps = 9/290 (3%)
Frame = +2
Query: 138 LMERLSVDYGKKSKLEFSIYP-APQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYD 196
L+E+L+ + KK +S++P ++S VV+PYNS+LT +++DC ++DN A+
Sbjct: 65 LLEKLNDRFPKKLIQTYSVFPNVDEISDVVVQPYNSLLTLKRLTQNADCVVVLDNTALNR 244
Query: 197 ICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLAT 256
I L I+ PT+ +N+L+S ++S+ T +LR+ G +N DL +L+P PR+HF +
Sbjct: 245 IAADRLHIDTPTFAQVNQLVSTVMSTSTTTLRYPGYMNNDLIGLIASLIPTPRLHFLMTG 424
Query: 257 YAPVIS-AEKAYHEQLSVAEITNACFEPANQMVKCDPRHGK----YMACCLLYRGDVVPK 311
Y P+ + ++ A + +V ++ +P N MV P H + Y++ + +G+V P
Sbjct: 425 YTPLTTDSQVANVRKTTVLDVMRRLLQPKNMMVST-PVHRQANHCYISILNIIQGEVDPT 601
Query: 312 DVNAAIAAIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAE 371
V+ ++ I+ ++ QF+ W P +V ++ + P V ++ + ML+N T+I+
Sbjct: 602 QVHKSLQRIRERKLAQFIPWGPASIQVALSRKSPYVQTAHRVSGL-----MLANHTSISH 766
Query: 372 AWARLDHKFDLMYAKRAFVHWYVGEGMEE---GEFSEAREDMAALEKDYE 418
+ R+ ++D + + AF+ + E + + EF +RE + L +Y+
Sbjct: 767 LFERILRQYDKLRKREAFMDQFKKEAIFKDNLDEFDNSREALQLLVDEYQ 916
>25015
Length = 458
Score = 114 bits (284), Expect = 1e-25, Method: Compositional matrix adjust.
Identities = 52/119 (43%), Positives = 74/119 (62%)
Frame = -3
Query: 6 WELYCLEHGIQPDGQMPSDKTIGGGDDSFTTFFCETGAGKHVPRAVFVDLEPTVIDEIRN 65
WE+ EHGI P G D + + ++ E GK+VPRAV VDLEP +D +R+
Sbjct: 360 WEVISDEHGIDPTGTYHGDSDLQ--LERINVYYNEATGGKYVPRAVLVDLEPGTMDSVRS 187
Query: 66 GPYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDPVLDRIRKLSDQCTGLQGFLVFH 124
GP+ Q+F P+ + G+ A NN+A+GHYT G E++D VLD +RK ++ C LQGF + H
Sbjct: 186 GPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQLTH 10
>28905
Length = 425
Score = 90.9 bits (224), Expect = 8e-19, Method: Composition-based stats.
Identities = 37/103 (35%), Positives = 59/103 (57%)
Frame = -1
Query: 243 NLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCL 302
N+VP+PR+HF + +AP+ S + L+V E+T F+ N M CDPRHG+Y+
Sbjct: 380 NMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAA 201
Query: 303 LYRGDVVPKDVNAAIAAIKTKRSIQFVDWCPTGFKVGINYQPP 345
++RG + K+V+ + ++ K S FV+W P K + PP
Sbjct: 200 MFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPP 72
>31457
Length = 1530
Score = 88.2 bits (217), Expect = 6e-18, Method: Compositional matrix adjust.
Identities = 40/124 (32%), Positives = 69/124 (55%)
Frame = +3
Query: 296 KYMACCLLYRGDVVPKDVNAAIAAIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAK 355
KY+ ++RG + K+V+ + ++ K S FV+W P K + PP
Sbjct: 234 KYLTVAAMFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPR--------G 389
Query: 356 VQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEK 415
++ + + N+TAI E + R+ +F M+ ++AF+HWY GEGM+E EF+EA +M L
Sbjct: 390 LKMSSTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS 569
Query: 416 DYEE 419
+Y++
Sbjct: 570 EYQQ 581
>39157
Length = 488
Score = 77.0 bits (188), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 42/112 (37%), Positives = 63/112 (56%), Gaps = 3/112 (2%)
Frame = -1
Query: 1 MGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFTTFFCETGAGKHVPRAVFVDLEPTVI 60
+G WE+ EHGI P G D + + ++ E GK+VPRAV VDLEP +
Sbjct: 398 IGAKFWEVISDEHGIDPTGTYHGDSDLQ--LERINVYYNEATGGKYVPRAVLVDLEPGTM 225
Query: 61 DEIRNG-PYR-QLFHPEQLITGKEDAANNYARGHYTI-GKEIIDPVLDRIRK 109
D +R+G P+ ++F P+ + G+ A NN+ + T G E++D VLD +RK
Sbjct: 224 DSVRSGSPFGPKIFRPDNFVFGQSGAGNNWGQKDTTQRGAELVDSVLDVVRK 69
>13964
Length = 528
Score = 33.5 bits (75), Expect = 0.15, Method: Compositional matrix adjust.
Identities = 14/16 (87%), Positives = 16/16 (100%)
Frame = +2
Query: 409 DMAALEKDYEEVGIDS 424
D+AALEKDYEEVG+DS
Sbjct: 230 DLAALEKDYEEVGVDS 277
>26569
Length = 1180
Score = 32.0 bits (71), Expect = 0.50, Method: Compositional matrix adjust.
Identities = 20/62 (32%), Positives = 26/62 (41%)
Frame = +1
Query: 358 RAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDY 417
R V +N A +E W + KF A+ HW G+G E + S AR L D
Sbjct: 481 RGVNRPANYCAGSETWTQRKKKFSNWNAR----HWKRGKGKERRKISLARAGGVGLAVDT 648
Query: 418 EE 419
E
Sbjct: 649 SE 654
>06591
Length = 978
Score = 29.6 bits (65), Expect = 2.7, Method: Compositional matrix adjust.
Identities = 19/57 (33%), Positives = 24/57 (42%)
Frame = -2
Query: 305 RGDVVPKDVNAAIAAIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVC 361
RG VP + T S DWCP G + G+ YQ T D+A Q +C
Sbjct: 767 RGSCVPSE---------TSLSTPVTDWCPQGDQPGVVYQNLTCA---DVATSQPWLC 633
>18555
Length = 596
Score = 28.5 bits (62), Expect = 6.0, Method: Compositional matrix adjust.
Identities = 16/48 (33%), Positives = 26/48 (54%)
Frame = -1
Query: 217 SQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAE 264
+QI S S + AL +D F + + P+++FPL+ PV+SA
Sbjct: 344 NQIFS*S*KSFCYSLALTIDKKHFNKDRLLKPKVNFPLS*GQPVLSAS 201
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000311579 | hsapiens_gene_ensembl | Tankyrase-1
(EC 2.4.2.30) (TANK1) (Tankyrase I) (TNKS-1) (TRF1- interacting
ankyrin-related ADP-ribose polymerase).
[Source:Uniprot/SWISSPROT;Acc:O95271]
(1327 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
06253 601 e-172
25470 208 1e-53
09292 118 1e-26
14005 94 4e-19
11295 90 6e-18
02114 88 3e-17
13462 83 8e-16
19166 77 4e-14
05924 76 1e-13
21532 70 5e-12
16561 67 6e-11
08473 64 5e-10
00540 64 6e-10
02055 63 8e-10
03590 49 1e-09
28113 62 1e-09
09180 60 7e-09
28494 59 9e-09
20792 57 4e-08
30978 54 3e-07
15359 53 8e-07
34789 52 1e-06
38834 52 1e-06
20036 52 1e-06
12417 52 2e-06
27067 52 2e-06
27108 51 2e-06
33144 51 4e-06
22305 49 2e-05
30217 48 3e-05
20121 48 3e-05
28691 48 3e-05
15772 46 1e-04
11861 43 7e-04
05396 43 8e-04
20884 41 8e-04
13622 42 0.001
13900 42 0.002
22269 42 0.002
27416 41 0.003
17893 40 0.005
33484 40 0.007
18216 40 0.007
25464 40 0.009
05693 40 0.009
12662 40 0.009
04480 39 0.010
05854 39 0.010
36879 39 0.011
07234 39 0.017
21751 39 0.020
02069 38 0.030
09214 37 0.046
30463 37 0.049
02351 37 0.072
08755 36 0.084
35952 36 0.10
06293 36 0.11
04513 35 0.23
18883 34 0.32
36917 34 0.36
01194 34 0.46
28491 33 0.55
28345 33 0.56
10413 33 1.0
34970 33 1.0
20955 32 1.3
20988 32 1.9
>06253
Length = 1049
Score = 601 bits (1550), Expect = e-172, Method: Compositional matrix adjust.
Identities = 289/342 (84%), Positives = 315/342 (92%)
Frame = -1
Query: 215 RKSSPLHFAAGFGRKDVVEHLLQMGANVHARDDGGLIPLHNACSFGHAEVVSLLLCQGAD 274
RKS+PLHFAAGFGRKDVVEHLL+ GANVHARDDGGLIPLHNACSFGHAEVV LLL GAD
Sbjct: 1049 RKSTPLHFAAGFGRKDVVEHLLENGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGAD 870
Query: 275 PNARDNWNYTPLHEAAIKGKIDVCIVLLQHGADPNIRNTDGKSALDLADPSAKAVLTGEY 334
PNARDNWNYTPLHEAAIKGKIDVCIVLLQ ADPNIRNTDGK+ALDLAD SAKAVLTGEY
Sbjct: 869 PNARDNWNYTPLHEAAIKGKIDVCIVLLQQCADPNIRNTDGKTALDLADASAKAVLTGEY 690
Query: 335 KKDELLEAARSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGAD 394
KKDELLEAARSGNEE++MALLTPLNVNCHASDGRKSTPLHLAAGYNR RIVQLLLQHGAD
Sbjct: 689 KKDELLEAARSGNEEQMMALLTPLNVNCHASDGRKSTPLHLAAGYNRTRIVQLLLQHGAD 510
Query: 395 VHAKDKGGLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLL 454
VHAKDKGGLVPLHNACSYGH+EVTE+LL GA VNA+DLWQFTPLHEAASK+RVEVCSLL
Sbjct: 509 VHAKDKGGLVPLHNACSYGHFEVTEMLLXAGASVNAVDLWQFTPLHEAASKSRVEVCSLL 330
Query: 455 LSHGADPTLVNCHGKSAVDMAPTPELRERLTYEFKGHSLLQAAREADLAKVKKTLALEII 514
L+HGADP LVNCH KS +D+APT EL+ER+ +E+KGHSLL+ AR+ADLA+VKK LA++I+
Sbjct: 329 LAHGADPNLVNCHSKSIIDVAPTRELQERIQFEYKGHSLLEGARQADLARVKKYLAVDIV 150
Query: 515 NFKQPQSHETALHCAVASLHPKRKQVTELLLRKGANVNEKNK 556
NFK P + +TALHCA AS PKRKQV ELL+RKG N+NEK K
Sbjct: 149 NFKHPYNGDTALHCAAASPFPKRKQVVELLVRKGGNLNEKTK 24
Score = 291 bits (745), Expect = 1e-78, Method: Compositional matrix adjust.
Identities = 138/267 (51%), Positives = 179/267 (67%)
Frame = -1
Query: 683 RHSTPLHFAAGYNRVSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGAS 742
R STPLHFAAG+ R VVE+LL +GA+VHA+D GGL+PLHNACS+GH EV +LL+RHGA
Sbjct: 1049 RKSTPLHFAAGFGRKDVVEHLLENGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGAD 870
Query: 743 VNVADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPLDLVKEGDTDIQXXXX 802
N D W +TPLHEAA KGK ++C +LL+ ADP +N DG T LDL +
Sbjct: 869 PNARDNWNYTPLHEAAIKGKIDVCIVLLQQCADPNIRNTDGKTALDLADASAKAVLTGEY 690
Query: 803 XXXXXXXXXXXXXXXRVQKLCTPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGAD 862
++ L TP N+NC + GR STPLHLAAGYN + + LL+HGAD
Sbjct: 689 KKDELLEAARSGNEEQMMALLTPLNVNCHASDGRKSTPLHLAAGYNRTRIVQLLLQHGAD 510
Query: 863 VNAQDKGGLIPLHNAASYGHVDIAALLIKYNTCVNATDKWAFTPLHEAAQKGRTQLCALL 922
V+A+DKGGL+PLHNA SYGH ++ +L+ VNA D W FTPLHEAA K R ++C+LL
Sbjct: 509 VHAKDKGGLVPLHNACSYGHFEVTEMLLXAGASVNAVDLWQFTPLHEAASKSRVEVCSLL 330
Query: 923 LAHGADPTMKNQEGQTPLDLATADDIR 949
LAHGADP + N ++ +D+A +++
Sbjct: 329 LAHGADPNLVNCHSKSIIDVAPTRELQ 249
Score = 240 bits (612), Expect = 3e-63, Method: Compositional matrix adjust.
Identities = 142/340 (41%), Positives = 194/340 (57%), Gaps = 8/340 (2%)
Frame = -1
Query: 537 RKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTALH 596
RK V E LL GANV+ ++ + PLH A H +V+++L +HGA NA D T LH
Sbjct: 1010 RKDVVEHLLENGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGADPNARDNWNYTPLH 831
Query: 597 RAALAGHLQTCRLLLSYGSDPSIISLQGFTAAQMGNEAVQQILSESTPIRTSDVDYR--- 653
AA+ G + C +LL +DP+I + G TA + + + + +L+ +Y+
Sbjct: 830 EAAIKGKIDVCIVLLQQCADPNIRNTDGKTALDLADASAKAVLTG---------EYKKDE 678
Query: 654 LLEASKAGDLETVKQLCSSQNVNCRDLEGRHSTPLHFAAGYNRVSVVEYLLHHGADVHAK 713
LLEA+++G+ E + L + NVNC +GR STPLH AAGYNR +V+ LL HGADVHAK
Sbjct: 677 LLEAARSGNEEQMMALLTPLNVNCHASDGRKSTPLHLAAGYNRTRIVQLLLQHGADVHAK 498
Query: 714 DKGGLVPLHNACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAAAKGKYEICKLLLKHG 773
DKGGLVPLHNACSYGH+EV E+L+ GASVN DLW+FTPLHEAA+K + E+C LLL HG
Sbjct: 497 DKGGLVPLHNACSYGHFEVTEMLLXAGASVNAVDLWQFTPLHEAASKSRVEVCSLLLAHG 318
Query: 774 ADPTKKNRDGNTPLDL--VKEGDTDIQXXXXXXXXXXXXXXXXXXXRVQKLCTPENINCR 831
ADP N + +D+ +E IQ RV+K + +N +
Sbjct: 317 ADPNLVNCHSKSIIDVAPTRELQERIQ-FEYKGHSLLEGARQADLARVKKYLAVDIVNFK 141
Query: 832 DTQGRNSTPLHLAAGY---NNLEVAEYLLEHGADVNAQDK 868
T LH AA +V E L+ G ++N + K
Sbjct: 140 HPYN-GDTALHCAAASPFPKRKQVVELLVRKGGNLNEKTK 24
Score = 175 bits (444), Expect = 8e-44, Method: Compositional matrix adjust.
Identities = 102/221 (46%), Positives = 138/221 (62%), Gaps = 5/221 (2%)
Frame = -1
Query: 185 ELLEACRNGDVSRVKRLVDAANVNAKDMAGRKSSPLHFAAGFGRKDVVEHLLQMGANVHA 244
ELLEA R+G+ ++ L+ NVN GRKS+PLH AAG+ R +V+ LLQ GA+VHA
Sbjct: 680 ELLEAARSGNEEQMMALLTPLNVNCHASDGRKSTPLHLAAGYNRTRIVQLLLQHGADVHA 501
Query: 245 RDDGGLIPLHNACSFGHAEVVSLLLCQGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQH 304
+D GGL+PLHNACS+GH EV +LL GA NA D W +TPLHEAA K +++VC +LL H
Sbjct: 500 KDKGGLVPLHNACSYGHFEVTEMLLXAGASVNAVDLWQFTPLHEAASKSRVEVCSLLLAH 321
Query: 305 GADPNIRNTDGKSALDLADP-SAKAVLTGEYKKDELLEAARSGNEEKLMALLTPLNVNC- 362
GADPN+ N KS +D+A + + EYK LLE AR + ++ L VN
Sbjct: 320 GADPNLVNCHSKSIIDVAPTRELQERIQFEYKGHSLLEGARQADLARVKKYLAVDIVNFK 141
Query: 363 HASDGRKSTPLHLAAGY---NRVRIVQLLLQHGADVHAKDK 400
H +G T LH AA R ++V+LL++ G +++ K K
Sbjct: 140 HPYNG--DTALHCAAASPFPKRKQVVELLVRKGGNLNEKTK 24
>25470
Length = 400
Score = 208 bits (530), Expect = 1e-53, Method: Compositional matrix adjust.
Identities = 101/113 (89%), Positives = 105/113 (92%)
Frame = -3
Query: 222 FAAGFGRKDVVEHLLQMGANVHARDDGGLIPLHNACSFGHAEVVSLLLCQGADPNARDNW 281
AAGFGRKDVVEHLL+ GANVHARDDGGLIPLHNACSFGHAEVV LLL GADPNARDNW
Sbjct: 380 LAAGFGRKDVVEHLLENGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGADPNARDNW 201
Query: 282 NYTPLHEAAIKGKIDVCIVLLQHGADPNIRNTDGKSALDLADPSAKAVLTGEY 334
NYTPLHEAAIKGKIDVCIVLLQ ADPNIRNTDGK+ALDLAD SAKAVLTG++
Sbjct: 200 NYTPLHEAAIKGKIDVCIVLLQQCADPNIRNTDGKTALDLADASAKAVLTGKH 42
Score = 133 bits (335), Expect = 4e-31, Method: Compositional matrix adjust.
Identities = 61/100 (61%), Positives = 76/100 (76%)
Frame = -3
Query: 690 FAAGYNRVSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGASVNVADLW 749
AAG+ R VVE+LL +GA+VHA+D GGL+PLHNACS+GH EV +LL+RHGA N D W
Sbjct: 380 LAAGFGRKDVVEHLLENGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGADPNARDNW 201
Query: 750 KFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPLDL 789
+TPLHEAA KGK ++C +LL+ ADP +N DG T LDL
Sbjct: 200 NYTPLHEAAIKGKIDVCIVLLQQCADPNIRNTDGKTALDL 81
Score = 129 bits (323), Expect = 1e-29, Method: Compositional matrix adjust.
Identities = 59/101 (58%), Positives = 79/101 (78%)
Frame = -3
Query: 375 LAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGACVNAMDLW 434
LAAG+ R +V+ LL++GA+VHA+D GGL+PLHNACS+GH EV +LLL+HGA NA D W
Sbjct: 380 LAAGFGRKDVVEHLLENGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGADPNARDNW 201
Query: 435 QFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMA 475
+TPLHEAA K +++VC +LL ADP + N GK+A+D+A
Sbjct: 200 NYTPLHEAAIKGKIDVCIVLLQQCADPNIRNTDGKTALDLA 78
Score = 118 bits (295), Expect = 2e-26, Method: Compositional matrix adjust.
Identities = 55/103 (53%), Positives = 76/103 (73%)
Frame = -3
Query: 843 LAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAALLIKYNTCVNATDKW 902
LAAG+ +V E+LLE+GA+V+A+D GGLIPLHNA S+GH ++ LL+++ NA D W
Sbjct: 380 LAAGFGRKDVVEHLLENGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGADPNARDNW 201
Query: 903 AFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTPLDLATA 945
+TPLHEAA KG+ +C +LL ADP ++N +G+T LDLA A
Sbjct: 200 NYTPLHEAAIKGKIDVCIVLLQQCADPNIRNTDGKTALDLADA 72
Score = 75.1 bits (183), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 39/104 (37%), Positives = 60/104 (57%)
Frame = -3
Query: 537 RKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTALH 596
RK V E LL GANV+ ++ + PLH A H +V+++L +HGA NA D T LH
Sbjct: 362 RKDVVEHLLENGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGADPNARDNWNYTPLH 183
Query: 597 RAALAGHLQTCRLLLSYGSDPSIISLQGFTAAQMGNEAVQQILS 640
AA+ G + C +LL +DP+I + G TA + + + + +L+
Sbjct: 182 EAAIKGKIDVCIVLLQQCADPNIRNTDGKTALDLADASAKAVLT 51
Score = 39.7 bits (91), Expect = 0.009, Method: Compositional matrix adjust.
Identities = 22/55 (40%), Positives = 33/55 (60%)
Frame = -3
Query: 564 VAAERAHNDVMEVLHKHGAKMNALDTLGQTALHRAALAGHLQTCRLLLSYGSDPS 618
+AA DV+E L ++GA ++A D G LH A GH + +LLL +G+DP+
Sbjct: 380 LAAGFGRKDVVEHLLENGANVHARDDGGLIPLHNACSFGHAEVVQLLLRHGADPN 216
>09292
Length = 1486
Score = 118 bits (296), Expect = 1e-26, Method: Compositional matrix adjust.
Identities = 108/374 (28%), Positives = 165/374 (44%), Gaps = 6/374 (1%)
Frame = -2
Query: 522 HETALH--CAVASLHPKRKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHK 579
HETALH C V S+ ++ +LL+ A+VN +N TPLH+ A H ++E L +
Sbjct: 1362 HETALHAVCYVGSV-----KMASVLLKHXADVNARNNVDRTPLHIXAIEGHLGLVEELVR 1198
Query: 580 HGAKMNALDTLGQTALHRAALAGHLQTCRLLLSYGSDPSIISLQGFTAAQMG-NEAVQQI 638
HGA NA D T + A + R LL G+ + + F A + G +E VQ +
Sbjct: 1197 HGADFNAEDKDHLTPVFNACVKNDTDIVRYLLESGARANTTARPIFHAVKYGYSEIVQLL 1018
Query: 639 LSESTPIRT-SDVDYRLLEASKAGDLETVKQ-LCSSQNVNCRDLEGRHSTPLHFAA-GYN 695
L + + L A + G++E + + + NVN D +G +TPLH + +
Sbjct: 1017 LVHGAAVNSLPGTKSPLHIACRNGNIEMARTVIIAGANVNAVDKDG--NTPLHISVRAPS 844
Query: 696 RVSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGASVNVADLWKFTPLH 755
+V L+ GA+V + +PLH AC Y + E A LL+ G+ N +TPLH
Sbjct: 843 SAQLVRLLIRFGANVKWGNDNQQIPLHLACLYSNLETARLLLHCGSCSNELSSKLWTPLH 664
Query: 756 EAAAKGKYEICKLLLKHGADPTKKNRDGNTPLDLVKEGDTDIQXXXXXXXXXXXXXXXXX 815
A G +I +L+L +G +D+
Sbjct: 663 YAVIGGNVDIVRLVL---------------------QGSSDVN----------------- 598
Query: 816 XXRVQKLCTPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLH 875
+P+ GRN+ PLHLA + +A LL HGA+VN G PLH
Sbjct: 597 --------SPD--------GRNNAPLHLACMKQCIGIARCLLRHGANVNVSGYNGRTPLH 466
Query: 876 NAASYGHVDIAALL 889
A S+ ++++ LL
Sbjct: 465 IAISHHNLELVLLL 424
Score = 117 bits (294), Expect = 2e-26, Method: Compositional matrix adjust.
Identities = 93/301 (30%), Positives = 134/301 (44%), Gaps = 29/301 (9%)
Frame = -2
Query: 674 NVNCRDLEGRHSTPLHFAAGYNRVSVVEYLLHHGADVHAKDKGGLVPLHNAC-------- 725
+VN R+ R TPLH A + +VE L+ HGAD +A+DK L P+ NAC
Sbjct: 1287 DVNARNNVDR--TPLHIXAIEGHLGLVEELVRHGADFNAEDKDHLTPVFNACVKNDTDIV 1114
Query: 726 ---------------------SYGHYEVAELLVRHGASVNVADLWKFTPLHEAAAKGKYE 764
YG+ E+ +LL+ HGA+VN K +PLH A G E
Sbjct: 1113 RYLLESGARANTTARPIFHAVKYGYSEIVQLLLVHGAAVNSLPGTK-SPLHIACRNGNIE 937
Query: 765 ICKLLLKHGADPTKKNRDGNTPLDLVKEGDTDIQXXXXXXXXXXXXXXXXXXXRVQKLCT 824
+ + ++ GA+ ++DGNTPL + + Q + +L
Sbjct: 936 MARTVIIAGANVNAVDKDGNTPLHISVRAPSSAQ--------------------LVRLLI 817
Query: 825 PENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVD 884
N + PLHLA Y+NLE A LL G+ N PLH A G+VD
Sbjct: 816 RFGANVKWGNDNQQIPLHLACLYSNLETARLLLHCGSCSNELSSKLWTPLHYAVIGGNVD 637
Query: 885 IAALLIKYNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTPLDLAT 944
I L+++ ++ VN+ D PLH A K + LL HGA+ + G+TPL +A
Sbjct: 636 IVRLVLQGSSDVNSPDGRNNAPLHLACMKQCIGIARCLLRHGANVNVSGYNGRTPLHIAI 457
Query: 945 A 945
+
Sbjct: 456 S 454
Score = 105 bits (261), Expect = 2e-22, Method: Compositional matrix adjust.
Identities = 116/417 (27%), Positives = 170/417 (40%), Gaps = 3/417 (0%)
Frame = -2
Query: 373 LHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGACVNAMD 432
LH A V + L G V +D LH C G ++ +LLKH A VNA +
Sbjct: 1449 LHCAXQLQDVETLLAYLDIGMHVDTRDSHHETALHAVCYVGSVKMASVLLKHXADVNARN 1270
Query: 433 LWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMAPTPELRERLTYEFKGHS 492
TPLH A + + + L+ HGAD E ++ LT F
Sbjct: 1269 NVDRTPLHIXAIEGHLGLVEELVRHGADFN---------------AEDKDHLTPVFNA-- 1141
Query: 493 LLQAAREADLAKVKKTLALEIINFKQPQSHETALHCAVASLHPKRKQVTELLLRKGANVN 552
+ D+ + +P H ++ +LLL GA VN
Sbjct: 1140 --CVKNDTDIVRYLLESGARANTTARPIFHAVKY---------GYSEIVQLLLVHGAAVN 994
Query: 553 EKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTALHRAALA-GHLQTCRLLL 611
+PLH+A + ++ + GA +NA+D G T LH + A Q RLL+
Sbjct: 993 SL-PGTKSPLHIACRNGNIEMARTVIIAGANVNAVDKDGNTPLHISVRAPSSAQLVRLLI 817
Query: 612 SYGSDPSIISLQGFTAAQMGNEAVQQILSESTPIRTSDVDYRLLEASKAGDLETVKQL-- 669
+G++ + GN+ QQI P+ A +LET + L
Sbjct: 816 RFGAN-----------VKWGNDN-QQI-----PLHL---------ACLYSNLETARLLLH 715
Query: 670 CSSQNVNCRDLEGRHSTPLHFAAGYNRVSVVEYLLHHGADVHAKDKGGLVPLHNACSYGH 729
C S + +L + TPLH+A V +V +L +DV++ D PLH AC
Sbjct: 714 CGSCS---NELSSKLWTPLHYAVIGGNVDIVRLVLQGSSDVNSPDGRNNAPLHLACMKQC 544
Query: 730 YEVAELLVRHGASVNVADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTP 786
+A L+RHGA+VNV+ TPLH A + E+ LL GA+ + DGN P
Sbjct: 543 IGIARCLLRHGANVNVSGYNGRTPLHIAISHHNLELVLLLYMCGANDQLVDFDGNFP 373
Score = 103 bits (256), Expect = 7e-22, Method: Compositional matrix adjust.
Identities = 108/404 (26%), Positives = 167/404 (41%), Gaps = 4/404 (0%)
Frame = -2
Query: 349 EKLMALLTPLNVNCHAS--DGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPL 406
+ + LL L++ H D T LH V++ +LL+H ADV+A++ PL
Sbjct: 1428 QDVETLLAYLDIGMHVDTRDSHHETALHAVCYVGSVKMASVLLKHXADVNARNNVDRTPL 1249
Query: 407 HNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNC 466
H GH + E L++HGA NA D TP+ A KN ++ LL GA
Sbjct: 1248 HIXAIEGHLGLVEELVRHGADFNAEDKDHLTPVFNACVKNDTDIVRYLLESGA------- 1090
Query: 467 HGKSAVDMAPTPELRERLTYEFKGHSLLQAAREADLAKVKKTLALEIINFKQPQSHETAL 526
++ P + E L+ A L K L + N
Sbjct: 1089 --RANTTARPIFHAVKYGYSEIVQLLLVHGAAVNSLPGTKSPLHIACRN----------- 949
Query: 527 HCAVASLHPKRKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHN-DVMEVLHKHGAKMN 585
++ ++ GANVN +KD TPLH++ + ++ +L + GA +
Sbjct: 948 ---------GNIEMARTVIIAGANVNAVDKDGNTPLHISVRAPSSAQLVRLLIRFGANVK 796
Query: 586 ALDTLGQTALHRAALAGHLQTCRLLLSYGSDPSIISLQGFTAAQMGNEAVQQILSESTPI 645
+ Q LH A L +L+T RLLL GS NE ++ TP+
Sbjct: 795 WGNDNQQIPLHLACLYSNLETARLLLHCGS--------------CSNELSSKLW---TPL 667
Query: 646 RTSDVDYRLLEASKAGDLETVK-QLCSSQNVNCRDLEGRHSTPLHFAAGYNRVSVVEYLL 704
+ + G+++ V+ L S +VN D GR++ PLH A + + LL
Sbjct: 666 HYAVI---------GGNVDIVRLVLQGSSDVNSPD--GRNNAPLHLACMKQCIGIARCLL 520
Query: 705 HHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGASVNVADL 748
HGA+V+ G PLH A S+ + E+ LL GA+ + D
Sbjct: 519 RHGANVNVSGYNGRTPLHIAISHHNLELVLLLYMCGANDQLVDF 388
Score = 100 bits (248), Expect = 6e-21, Method: Compositional matrix adjust.
Identities = 85/273 (31%), Positives = 127/273 (46%), Gaps = 2/273 (0%)
Frame = -2
Query: 190 CRNGDVSRVKRLVD-AANVNAKDMAGRKSSPLHFAAGFGRKDVVEHLLQMGANVHARDDG 248
C G V L+ A+VNA++ R +PLH A G +VE L++ GA+ +A D
Sbjct: 1338 CYVGSVKMASVLLKHXADVNARNNVDR--TPLHIXAIEGHLGLVEELVRHGADFNAEDKD 1165
Query: 249 GLIPLHNACSFGHAEVVSLLLCQGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGADP 308
L P+ NAC ++V LL G AR N P+ A G ++ +LL HGA
Sbjct: 1164 HLTPVFNACVKNDTDIVRYLLESG----ARANTTARPIFHAVKYGYSEIVQLLLVHGA-- 1003
Query: 309 NIRNTDGKSALDLADPSAKAVLTGEYKKDELLEAARSGNEEKLMALLTPLNVNCHASDGR 368
AV + K L A R+GN E ++ N +A D
Sbjct: 1002 -------------------AVNSLPGTKSPLHIACRNGNIEMARTVIIA-GANVNAVDKD 883
Query: 369 KSTPLHLAA-GYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGAC 427
+TPLH++ + ++V+LL++ GA+V + +PLH AC Y + E LLL G+C
Sbjct: 882 GNTPLHISVRAPSSAQLVRLLIRFGANVKWGNDNQQIPLHLACLYSNLETARLLLHCGSC 703
Query: 428 VNAMDLWQFTPLHEAASKNRVEVCSLLLSHGAD 460
N + +TPLH A V++ L+L +D
Sbjct: 702 SNELSSKLWTPLHYAVIGGNVDIVRLVLQGSSD 604
Score = 92.4 bits (228), Expect = 1e-18, Method: Compositional matrix adjust.
Identities = 85/301 (28%), Positives = 125/301 (41%), Gaps = 14/301 (4%)
Frame = -2
Query: 657 ASKAGDLETV-KQLCSSQNVNCRDLEGRHSTPLHFAAGYNRVSVVEYLLHHGADVHAKDK 715
A + D+ET+ L +V+ RD H T LH V + LL H ADV+A++
Sbjct: 1440 AXQLQDVETLLAYLDIGMHVDTRD--SHHETALHAVCYVGSVKMASVLLKHXADVNARNN 1267
Query: 716 GGLVPLHNACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAAAKGKYEICKLLLKHGAD 775
PLH GH + E LVRHGA N D TP+ A K +I + LL+ GA
Sbjct: 1266 VDRTPLHIXAIEGHLGLVEELVRHGADFNAEDKDHLTPVFNACVKNDTDIVRYLLESGA- 1090
Query: 776 PTKKNRDGNTPLDLVKEGDTDI-QXXXXXXXXXXXXXXXXXXXRV-----------QKLC 823
+ N VK G ++I Q + +
Sbjct: 1089 --RANTTARPIFHAVKYGYSEIVQLLLVHGAAVNSLPGTKSPLHIACRNGNIEMARTVII 916
Query: 824 TPENINCRDTQGRNSTPLHLAA-GYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGH 882
N+N D G +TPLH++ ++ ++ L+ GA+V + IPLH A Y +
Sbjct: 915 AGANVNAVDKDG--NTPLHISVRAPSSAQLVRLLIRFGANVKWGNDNQQIPLHLACLYSN 742
Query: 883 VDIAALLIKYNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTPLDL 942
++ A LL+ +C N +TPLH A G + L+L +D + PL L
Sbjct: 741 LETARLLLHCGSCSNELSSKLWTPLHYAVIGGNVDIVRLVLQGSSDVNSPDGRNNAPLHL 562
Query: 943 A 943
A
Sbjct: 561 A 559
Score = 86.7 bits (213), Expect = 6e-17, Method: Compositional matrix adjust.
Identities = 78/258 (30%), Positives = 111/258 (43%), Gaps = 2/258 (0%)
Frame = -2
Query: 688 LHFAAGYNRVSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGASVNVAD 747
LH A V + L G V +D LH C G ++A +L++H A VN +
Sbjct: 1449 LHCAXQLQDVETLLAYLDIGMHVDTRDSHHETALHAVCYVGSVKMASVLLKHXADVNARN 1270
Query: 748 LWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPL-DLVKEGDTDIQXXXXXXXX 806
TPLH A +G + + L++HGAD +++D TP+ + + DTDI
Sbjct: 1269 NVDRTPLHIXAIEGHLGLVEELVRHGADFNAEDKDHLTPVFNACVKNDTDIVRYLLESGA 1090
Query: 807 XXXXXXXXXXXRVQKLCTPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQ 866
+T R P+ A Y E+ + LL HGA VN+
Sbjct: 1089 RA-----------------------NTTAR---PIFHAVKYGYSEIVQLLLVHGAAVNSL 988
Query: 867 DKGGLIPLHNAASYGHVDIAALLIKYNTCVNATDKWAFTPLHEAAQK-GRTQLCALLLAH 925
G PLH A G++++A +I VNA DK TPLH + + QL LL+
Sbjct: 987 -PGTKSPLHIACRNGNIEMARTVIIAGANVNAVDKDGNTPLHISVRAPSSAQLVRLLIRF 811
Query: 926 GADPTMKNQEGQTPLDLA 943
GA+ N Q PL LA
Sbjct: 810 GANVKWGNDNQQIPLHLA 757
Score = 82.4 bits (202), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 71/219 (32%), Positives = 104/219 (47%), Gaps = 2/219 (0%)
Frame = -2
Query: 189 ACRNGDVSRVKRLVDA-ANVNAKDMAGRKSSPLHFAA-GFGRKDVVEHLLQMGANVHARD 246
ACRNG++ + ++ A ANVNA D G ++PLH + +V L++ GANV +
Sbjct: 960 ACRNGNIEMARTVIIAGANVNAVDKDG--NTPLHISVRAPSSAQLVRLLIRFGANVKWGN 787
Query: 247 DGGLIPLHNACSFGHAEVVSLLLCQGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGA 306
D IPLH AC + + E LLL G+ N + +TPLH A I G +D+ ++LQ +
Sbjct: 786 DNQQIPLHLACLYSNLETARLLLHCGSCSNELSSKLWTPLHYAVIGGNVDIVRLVLQGSS 607
Query: 307 DPNIRNTDGKSALDLADPSAKAVLTGEYKKDELLEAARSGNEEKLMALLTPLNVNCHASD 366
D N + + L LA + + AR L NVN +
Sbjct: 606 DVNSPDGRNNAPLHLA------------CMKQCIGIARC-------LLRHGANVNVSGYN 484
Query: 367 GRKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVP 405
GR TPLH+A ++ + +V LL GA+ D G P
Sbjct: 483 GR--TPLHIAISHHNLELVLLLYMCGANDQLVDFDGNFP 373
Score = 59.7 bits (143), Expect = 7e-09, Method: Compositional matrix adjust.
Identities = 59/236 (25%), Positives = 96/236 (40%), Gaps = 2/236 (0%)
Frame = -2
Query: 711 HAKDKGGLVPLHNACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAAAKGKYEICKLLL 770
H + LH A E + G V+ D T LH G ++ +LL
Sbjct: 1479 HEQQPASFCALHCAXQLQDVETLLAYLDIGMHVDTRDSHHETALHAVCYVGSVKMASVLL 1300
Query: 771 KHGADPTKKNRDGNTPLDLVK-EGDTDIQXXXXXXXXXXXXXXXXXXXRVQKLCT-PENI 828
KH AD +N TPL + EG + V++L +
Sbjct: 1299 KHXADVNARNNVDRTPLHIXAIEGHLGL---------------------VEELVRHGADF 1183
Query: 829 NCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAAL 888
N D + TP+ A N+ ++ YLLE GA N + P+ +A YG+ +I L
Sbjct: 1182 NAEDKD--HLTPVFNACVKNDTDIVRYLLESGARANTTAR----PIFHAVKYGYSEIVQL 1021
Query: 889 LIKYNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTPLDLAT 944
L+ + VN+ +PLH A + G ++ ++ GA+ +++G TPL ++
Sbjct: 1020 LLVHGAAVNSL-PGTKSPLHIACRNGNIEMARTVIIAGANVNAVDKDGNTPLHISV 856
Score = 55.5 bits (132), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 39/140 (27%), Positives = 65/140 (46%)
Frame = -2
Query: 828 INCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAA 887
++ RD+ + T LH ++++A LL+H ADVNA++ PLH A GH+ +
Sbjct: 1383 VDTRDSH--HETALHAVCYVGSVKMASVLLKHXADVNARNNVDRTPLHIXAIEGHLGLVE 1210
Query: 888 LLIKYNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTPLDLATADD 947
L+++ NA DK TP+ A K T + LL GA + + ++
Sbjct: 1209 ELVRHGADFNAEDKDHLTPVFNACVKNDTDIVRYLLESGARANTTARPIFHAVKYGYSEI 1030
Query: 948 IRALLIDAMPPEALPTCFKP 967
++ LL+ +LP P
Sbjct: 1029 VQLLLVHGAAVNSLPGTKSP 970
>14005
Length = 1745
Score = 94.0 bits (232), Expect = 4e-19, Method: Compositional matrix adjust.
Identities = 80/262 (30%), Positives = 118/262 (45%), Gaps = 4/262 (1%)
Frame = -1
Query: 686 TPLHFAAGYNRVSVVEYLLH-HGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGASVN 744
TPL A+ ++VV LL G DV+ +D+ L+ AC E+ + LVR+GA VN
Sbjct: 1739 TPLIIASRMGHLAVVSELLKVPGIDVNERDEKLRPALYFACMGNDIELVKQLVRYGARVN 1560
Query: 745 V--ADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPLDLVKEGDTDIQXXXX 802
+ W +TP H +G I LL+HGA+ + DG TPL + + D
Sbjct: 1559 AYSTETW-WTPFHACCKRGDPRIALYLLRHGANKESRTVDGKTPLVVACKNDK------- 1404
Query: 803 XXXXXXXXXXXXXXXRVQKLCTPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGAD 862
+ + N++C T +TP+H A N+E+ + L+ HGAD
Sbjct: 1403 ----------AEVALLLIRSGANVNVSCDITA---NTPVHFACQRPNIELLKRLVLHGAD 1263
Query: 863 VNAQDKGGLIPLHNAASYGHVDIAALLIKY-NTCVNATDKWAFTPLHEAAQKGRTQLCAL 921
V+ + G LH A+ G L+ + + VNA LH A + L L
Sbjct: 1262 VDKPNAKGHTALHVASVRGFKQHVIYLLDFCDAEVNAATLKGNNALHIACRGKHADLVEL 1083
Query: 922 LLAHGADPTMKNQEGQTPLDLA 943
LL GA+P +NQ G TP + A
Sbjct: 1082 LLHKGANPAQRNQRGWTPRNSA 1017
Score = 78.6 bits (192), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 77/259 (29%), Positives = 113/259 (43%), Gaps = 6/259 (2%)
Frame = -1
Query: 625 FTAAQMGNEAVQQILSESTPIRTSDVDYRLLEA----SKAGDLETVKQLCS-SQNVNCRD 679
A++MG+ AV L + I ++ D +L A D+E VKQL VN
Sbjct: 1730 IIASRMGHLAVVSELLKVPGIDVNERDEKLRPALYFACMGNDIELVKQLVRYGARVNAYS 1551
Query: 680 LEGRHSTPLHFAAGYNRVSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRH 739
E TP H + YLL HGA+ ++ G PL AC EVA LL+R
Sbjct: 1550 TET-WWTPFHACCKRGDPRIALYLLRHGANKESRTVDGKTPLVVACKNDKAEVALLLIRS 1374
Query: 740 GASVNVA-DLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPLDLVKEGDTDIQ 798
GA+VNV+ D+ TP+H A + E+ K L+ HGAD K N G+T L +
Sbjct: 1373 GANVNVSCDITANTPVHFACQRPNIELLKRLVLHGADVDKPNAKGHTALHVAS------- 1215
Query: 799 XXXXXXXXXXXXXXXXXXXRVQKLCTPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLE 858
+ C E +N +G N+ LH+A + ++ E LL
Sbjct: 1214 ----------VRGFKQHVIYLLDFCDAE-VNAATLKGNNA--LHIACRGKHADLVELLLH 1074
Query: 859 HGADVNAQDKGGLIPLHNA 877
GA+ +++ G P ++A
Sbjct: 1073 KGANPAQRNQRGWTPRNSA 1017
Score = 68.2 bits (165), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 66/226 (29%), Positives = 102/226 (45%), Gaps = 2/226 (0%)
Frame = -1
Query: 186 LLEACRNGDVSRVKRLVD-AANVNAKDMAGRKSSPLHFAAGFGRKDVVEHLLQMGANVHA 244
L AC D+ VK+LV A VNA +P H G + +LL+ GAN +
Sbjct: 1631 LYFACMGNDIELVKQLVRYGARVNAYSTETW-WTPFHACCKRGDPRIALYLLRHGANKES 1455
Query: 245 RDDGGLIPLHNACSFGHAEVVSLLLCQGADPNAR-DNWNYTPLHEAAIKGKIDVCIVLLQ 303
R G PL AC AEV LL+ GA+ N D TP+H A + I++ L+
Sbjct: 1454 RTVDGKTPLVVACKNDKAEVALLLIRSGANVNVSCDITANTPVHFACQRPNIELLKRLVL 1275
Query: 304 HGADPNIRNTDGKSALDLADPSAKAVLTGEYKKDELLEAARSGNEEKLMALLTPLNVNCH 363
HGAD + N G +AL + A+ G ++ ++ LL + +
Sbjct: 1274 HGADVDKPNAKGHTALHV--------------------ASVRGFKQHVIYLLDFCDAEVN 1155
Query: 364 ASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNA 409
A+ + + LH+A +V+LLL GA+ +++ G P ++A
Sbjct: 1154 AATLKGNNALHIACRGKHADLVELLLHKGANPAQRNQRGWTPRNSA 1017
Score = 67.8 bits (164), Expect = 3e-11, Method: Compositional matrix adjust.
Identities = 76/253 (30%), Positives = 115/253 (45%), Gaps = 6/253 (2%)
Frame = -1
Query: 540 VTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDT-LGQTALHRA 598
V+ELL G +VNE+++ L+ A ++++ L ++GA++NA T T H
Sbjct: 1697 VSELLKVPGIDVNERDEKLRPALYFACMGNDIELVKQLVRYGARVNAYSTETWWTPFHAC 1518
Query: 599 ALAGHLQTCRLLLSYGSDPSIISLQGFTAAQMGNEAVQQILSESTPIRTSDVDYRLLEAS 658
G + LL +G++ ES RT D L+ A
Sbjct: 1517 CKRGDPRIALYLLRHGAN-----------------------KES---RTVDGKTPLVVAC 1416
Query: 659 KAGDLETVKQLCSS---QNVNCRDLEGRHSTPLHFAAGYNRVSVVEYLLHHGADVHAKDK 715
K E L S NV+C D+ +TP+HFA + +++ L+ HGADV +
Sbjct: 1415 KNDKAEVALLLIRSGANVNVSC-DITA--NTPVHFACQRPNIELLKRLVLHGADVDKPNA 1245
Query: 716 GGLVPLHNACSYGHYE-VAELLVRHGASVNVADLWKFTPLHEAAAKGKY-EICKLLLKHG 773
G LH A G + V LL A VN A L LH A +GK+ ++ +LLL G
Sbjct: 1244 KGHTALHVASVRGFKQHVIYLLDFCDAEVNAATLKGNNALH-IACRGKHADLVELLLHKG 1068
Query: 774 ADPTKKNRDGNTP 786
A+P ++N+ G TP
Sbjct: 1067 ANPAQRNQRGWTP 1029
Score = 67.0 bits (162), Expect = 5e-11, Method: Compositional matrix adjust.
Identities = 58/192 (30%), Positives = 84/192 (43%), Gaps = 1/192 (0%)
Frame = -1
Query: 371 TPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGACVN- 429
TP H RI LL+HGA+ ++ G PL AC EV LL++ GA VN
Sbjct: 1535 TPFHACCKRGDPRIALYLLRHGANKESRTVDGKTPLVVACKNDKAEVALLLIRSGANVNV 1356
Query: 430 AMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMAPTPELRERLTYEFK 489
+ D+ TP+H A + +E+ L+ HGAD N G +A+ +A ++ + Y
Sbjct: 1355 SCDITANTPVHFACQRPNIELLKRLVLHGADVDKPNAKGHTALHVASVRGFKQHVIY--- 1185
Query: 490 GHSLLQAAREADLAKVKKTLALEIINFKQPQSHETALHCAVASLHPKRKQVTELLLRKGA 549
L E + A +K AL I + K + ELLL KGA
Sbjct: 1184 --LLDFCDAEVNAATLKGNNALHI------------------ACRGKHADLVELLLHKGA 1065
Query: 550 NVNEKNKDFMTP 561
N ++N+ TP
Sbjct: 1064 NPAQRNQRGWTP 1029
Score = 58.9 bits (141), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 39/116 (33%), Positives = 57/116 (49%), Gaps = 1/116 (0%)
Frame = -1
Query: 839 TPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAALLIKYNTCVNA 898
TP H + +A YLL HGA+ ++ G PL A ++A LLI+ VN
Sbjct: 1535 TPFHACCKRGDPRIALYLLRHGANKESRTVDGKTPLVVACKNDKAEVALLLIRSGANVNV 1356
Query: 899 T-DKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTPLDLATADDIRALLI 953
+ D A TP+H A Q+ +L L+ HGAD N +G T L +A+ + +I
Sbjct: 1355 SCDITANTPVHFACQRPNIELLKRLVLHGADVDKPNAKGHTALHVASVRGFKQHVI 1188
Score = 57.8 bits (138), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 37/112 (33%), Positives = 61/112 (54%), Gaps = 3/112 (2%)
Frame = -1
Query: 839 TPLHLAAGYNNLEVAEYLLE-HGADVNAQDKGGLIPLHNAASYGHVDIAALLIKYNTCVN 897
TPL +A+ +L V LL+ G DVN +D+ L+ A +++ L++Y VN
Sbjct: 1739 TPLIIASRMGHLAVVSELLKVPGIDVNERDEKLRPALYFACMGNDIELVKQLVRYGARVN 1560
Query: 898 A--TDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTPLDLATADD 947
A T+ W +TP H ++G ++ LL HGA+ + +G+TPL +A +D
Sbjct: 1559 AYSTETW-WTPFHACCKRGDPRIALYLLRHGANKESRTVDGKTPLVVACKND 1407
Score = 57.8 bits (138), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 66/261 (25%), Positives = 112/261 (42%), Gaps = 2/261 (0%)
Frame = -1
Query: 335 KKDELLEAARSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGAD 394
++ L+ A+R G+ + LL ++ + D + L+ A N + +V+ L+++GA
Sbjct: 1745 RETPLIIASRMGHLAVVSELLKVPGIDVNERDEKLRPALYFACMGNDIELVKQLVRYGAR 1566
Query: 395 VHA-KDKGGLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSL 453
V+A + P H C G + LL+HGA + + TPL A ++ EV L
Sbjct: 1565 VNAYSTETWWTPFHACCKRGDPRIALYLLRHGANKESRTVDGKTPLVVACKNDKAEVALL 1386
Query: 454 LLSHGADPTLVNCHGKSAVDMAPTPELRERLTYEFKGHSLLQAAREADLAKVKKTLALEI 513
L+ GA+ V+C + ++ + A + ++ K L L
Sbjct: 1385 LIRSGANVN-VSC--------------------DITANTPVHFACQRPNIELLKRLVLHG 1269
Query: 514 INFKQPQSH-ETALHCAVASLHPKRKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHND 572
+ +P + TALH VAS+ ++ V LL A VN LH+A H D
Sbjct: 1268 ADVDKPNAKGHTALH--VASVRGFKQHVIYLLDFCDAEVNAATLKGNNALHIACRGKHAD 1095
Query: 573 VMEVLHKHGAKMNALDTLGQT 593
++E+L GA + G T
Sbjct: 1094 LVELLLHKGANPAQRNQRGWT 1032
Score = 45.1 bits (105), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 29/85 (34%), Positives = 47/85 (55%), Gaps = 1/85 (1%)
Frame = -1
Query: 530 VASLHPKRKQVTELLLRKGANVNEK-NKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALD 588
V + + +V LL+R GANVN + TP+H A +R + ++++ L HGA ++ +
Sbjct: 1427 VVACKNDKAEVALLLIRSGANVNVSCDITANTPVHFACQRPNIELLKRLVLHGADVDKPN 1248
Query: 589 TLGQTALHRAALAGHLQTCRLLLSY 613
G TALH A++ G Q LL +
Sbjct: 1247 AKGHTALHVASVRGFKQHVIYLLDF 1173
>11295
Length = 1179
Score = 90.1 bits (222), Expect = 6e-18, Method: Compositional matrix adjust.
Identities = 79/256 (30%), Positives = 112/256 (43%), Gaps = 4/256 (1%)
Frame = +1
Query: 536 KRKQVTELLLR----KGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDTLG 591
+ +V ELLL G VN + D +T LH+A ++ +L K+GA ALD +G
Sbjct: 97 RNTEVAELLLDGWNGDGIAVNATSNDHVTALHIACCLDDREMASLLLKYGAYAMALDVIG 276
Query: 592 QTALHRAALAGHLQTCRLLLSYGSDPSIISLQGFTAAQMGNEAVQQILSESTPIRTSDVD 651
T LH A G RLLL SD + +L P+R
Sbjct: 277 HTPLHVACWCGSEGVTRLLLD-RSDVDVNALDH---------------DGKXPLRL---- 396
Query: 652 YRLLEASKAGDLETVKQLCSSQNVNCRDLEGRHSTPLHFAAGYNRVSVVEYLLHHGADVH 711
AS+ G ++QL N + + TP H A Y RV V+ L D+
Sbjct: 397 -----ASECGFHYIIRQL-LYHNADHTIRDAAEFTPFHCAIRYCRVLAVKTFLVWFPDLI 558
Query: 712 AKDKGGLVPLHNACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAAAKGKYEICKLLLK 771
L P AC E+ LL++ GASVN AD + +TPLH + +G + +LLL+
Sbjct: 559 HSFYNDLSPTFMACLQCDKEMLSLLIKFGASVNCADHYHYTPLHYISRRGHLTMLQLLLQ 738
Query: 772 HGADPTKKNRDGNTPL 787
A+P + +G TPL
Sbjct: 739 GKAEPNVVDDEGITPL 786
Score = 82.4 bits (202), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 79/285 (27%), Positives = 114/285 (40%), Gaps = 41/285 (14%)
Frame = +1
Query: 703 LLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVR----HGASVNVADLWKFTPLHEAA 758
LL GA ++ D GL LH+AC + EVAELL+ G +VN T LH A
Sbjct: 22 LLQGGAQIYWTDHRGLSALHHACIGRNTEVAELLLDGWNGDGIAVNATSNDHVTALHIAC 201
Query: 759 AKGKYEICKLLLKHGADPTKKNRDGNTPLDLV----KEGDTDIQXXXXXXXXXXXXXXXX 814
E+ LLLK+GA + G+TPL + EG T +
Sbjct: 202 CLDDREMASLLLKYGAYAMALDVIGHTPLHVACWCGSEGVTRLLLDR------------- 342
Query: 815 XXXRVQKLCTPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPL 874
+ ++N D G+ PL LA+ + LL H AD +D P
Sbjct: 343 ---------SDVDVNALDHDGK--XPLRLASECGFHYIIRQLLYHNADHTIRDAAEFTPF 489
Query: 875 HNAASYGHV---------------------------------DIAALLIKYNTCVNATDK 901
H A Y V ++ +LLIK+ VN D
Sbjct: 490 HCAIRYCRVLAVKTFLVWFPDLIHSFYNDLSPTFMACLQCDKEMLSLLIKFGASVNCADH 669
Query: 902 WAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTPLDLATAD 946
+ +TPLH +++G + LLL A+P + + EG TPL +A+ +
Sbjct: 670 YHYTPLHYISRRGHLTMLQLLLQGKAEPNVVDDEGITPLYIASCE 804
Score = 81.3 bits (199), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 84/267 (31%), Positives = 111/267 (41%), Gaps = 6/267 (2%)
Frame = +1
Query: 215 RKSSPLHFAAGFGRKDVVEHLLQMGAN-----VHARDDGGLIPLHNACSFGHAEVVSLLL 269
R S LH A GR V LL G N V+A + + LH AC E+ SLLL
Sbjct: 61 RGLSALHHAC-IGRNTEVAELLLDGWNGDGIAVNATSNDHVTALHIACCLDDREMASLLL 237
Query: 270 CQGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHG-ADPNIRNTDGKSALDLADPSAKA 328
GA A D +TPLH A G V +LL D N + DGK L LA
Sbjct: 238 KYGAYAMALDVIGHTPLHVACWCGSEGVTRLLLDRSDVDVNALDHDGKXPLRLA------ 399
Query: 329 VLTGEYKKDELLEAARSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLL 388
+ G + LL N + D + TP H A Y RV V+
Sbjct: 400 --------------SECGFHYIIRQLLYH-NADHTIRDAAEFTPFHCAIRYCRVLAVKTF 534
Query: 389 LQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASKNRV 448
L D+ L P AC E+ LL+K GA VN D + +TPLH + + +
Sbjct: 535 LVWFPDLIHSFYNDLSPTFMACLQCDKEMLSLLIKFGASVNCADHYHYTPLHYISRRGHL 714
Query: 449 EVCSLLLSHGADPTLVNCHGKSAVDMA 475
+ LLL A+P +V+ G + + +A
Sbjct: 715 TMLQLLLQGKAEPNVVDDEGITPLYIA 795
Score = 73.9 bits (180), Expect = 4e-13, Method: Compositional matrix adjust.
Identities = 85/308 (27%), Positives = 127/308 (41%), Gaps = 6/308 (1%)
Frame = +1
Query: 314 DGKSALDLADPSAKAVLTGEYKKDELLEAARSGNEEKLMALLTPLN---VNCHASDGRKS 370
D ++ L L A+ T L A N E LL N + +A+
Sbjct: 1 DRQTVLTLLQGGAQIYWTDHRGLSALHHACIGRNTEVAELLLDGWNGDGIAVNATSNDHV 180
Query: 371 TPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLL-KHGACVN 429
T LH+A + + LLL++GA A D G PLH AC G VT LLL + VN
Sbjct: 181 TALHIACCLDDREMASLLLKYGAYAMALDVIGHTPLHVACWCGSEGVTRLLLDRSDVDVN 360
Query: 430 AMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMAPTPELRERLTYEFK 489
A+D PL A+ + LL H AD T+ + A + P
Sbjct: 361 ALDHDGKXPLRLASECGFHYIIRQLLYHNADHTI-----RDAAEFTP------------- 486
Query: 490 GHSLLQAAREADLAKVKKTLAL--EIINFKQPQSHETALHCAVASLHPKRKQVTELLLRK 547
A R + VK L ++I+ T + C K++ LL++
Sbjct: 487 ---FHCAIRYCRVLAVKTFLVWFPDLIHSFYNDLSPTFMACLQCD-----KEMLSLLIKF 642
Query: 548 GANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTALHRAALAGHLQTC 607
GA+VN + TPLH + R H ++++L + A+ N +D G T L+ A+ GH+
Sbjct: 643 GASVNCADHYHYTPLHYISRRGHLTMLQLLLQGKAEPNVVDDEGITPLYIASCEGHVTIV 822
Query: 608 RLLLSYGS 615
+LL G+
Sbjct: 823 NILLQSGA 846
Score = 68.2 bits (165), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 76/279 (27%), Positives = 121/279 (43%), Gaps = 21/279 (7%)
Frame = +1
Query: 385 VQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLK----HGACVNAMDLWQFTPLH 440
V LLQ GA ++ D GL LH+AC + EV ELLL G VNA T LH
Sbjct: 13 VLTLLQGGAQIYWTDHRGLSALHHACIGRNTEVAELLLDGWNGDGIAVNATSNDHVTALH 192
Query: 441 EAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMA-------PTPELRERLTYEFK---- 489
A + E+ SLLL +GA ++ G + + +A T L +R +
Sbjct: 193 IACCLDDREMASLLLKYGAYAMALDVIGHTPLHVACWCGSEGVTRLLLDRSDVDVNALDH 372
Query: 490 -GHSLLQAAREADLAKVKKTLALEIINFKQPQSHE-TALHCAVASLHPKRKQVTELLLRK 547
G L+ A E + + L + + E T HCA+ R + L
Sbjct: 373 DGKXPLRLASECGFHYIIRQLLYHNADHTIRDAAEFTPFHCAIRYC---RVLAVKTFLVW 543
Query: 548 GANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTALHRAALAGHLQTC 607
++ + ++P +A + +++ +L K GA +N D T LH + GHL
Sbjct: 544 FPDLIHSFYNDLSPTFMACLQCDKEMLSLLIKFGASVNCADHYHYTPLHYISRRGHLTML 723
Query: 608 RLLLSYGSDPSIISLQGFT----AAQMGNEAVQQILSES 642
+LLL ++P+++ +G T A+ G+ + IL +S
Sbjct: 724 QLLLQGKAEPNVVDDEGITPLYIASCEGHVTIVNILLQS 840
Score = 68.2 bits (165), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 68/249 (27%), Positives = 99/249 (39%), Gaps = 1/249 (0%)
Frame = +1
Query: 684 HSTPLHFAAGYNRVSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLV-RHGAS 742
H T LH A + + LL +GA A D G PLH AC G V LL+ R
Sbjct: 175 HVTALHIACCLDDREMASLLLKYGAYAMALDVIGHTPLHVACWCGSEGVTRLLLDRSDVD 354
Query: 743 VNVADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPLDLVKEGDTDIQXXXX 802
VN D PL A+ G + I + LL H AD T ++ TP
Sbjct: 355 VNALDHDGKXPLRLASECGFHYIIRQLLYHNADHTIRDAAEFTPFHCAIR---------- 504
Query: 803 XXXXXXXXXXXXXXXRVQKLCTPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGAD 862
+ + P+ I+ + + +P +A + E+ L++ GA
Sbjct: 505 --------YCRVLAVKTFLVWFPDLIH---SFYNDLSPTFMACLQCDKEMLSLLIKFGAS 651
Query: 863 VNAQDKGGLIPLHNAASYGHVDIAALLIKYNTCVNATDKWAFTPLHEAAQKGRTQLCALL 922
VN D PLH + GH+ + LL++ N D TPL+ A+ +G + +L
Sbjct: 652 VNCADHYHYTPLHYISRRGHLTMLQLLLQGKAEPNVVDDEGITPLYIASCEGHVTIVNIL 831
Query: 923 LAHGADPTM 931
L GA M
Sbjct: 832 LQSGAKIYM 858
Score = 52.0 bits (123), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 80/292 (27%), Positives = 115/292 (39%), Gaps = 54/292 (18%)
Frame = +1
Query: 183 LRELLEACRNGDVSRVKRLVDAAN-----VNAKDMAGRKSSPLHFAAGFGRKDVVEHLLQ 237
L L AC + + L+D N VNA + + LH A +++ LL+
Sbjct: 67 LSALHHACIGRNTEVAELLLDGWNGDGIAVNAT--SNDHVTALHIACCLDDREMASLLLK 240
Query: 238 MGANVHARDDGGLIPLHNACSFGHAEVVSLLLCQG-ADPNARDNWNYTPLHEAAIKGKID 296
GA A D G PLH AC G V LLL + D NA D+ PL A+ G
Sbjct: 241 YGAYAMALDVIGHTPLHVACWCGSEGVTRLLLDRSDVDVNALDHDGKXPLRLASECGFHY 420
Query: 297 VCIVLLQHGADPNIRNTDGKSALDLADPSAK--AVLTGEYKKDELLEA----------AR 344
+ LL H AD IR+ + A + AV T +L+ + A
Sbjct: 421 IIRQLLYHNADHTIRDAAEFTPFHCAIRYCRVLAVKTFLVWFPDLIHSFYNDLSPTFMAC 600
Query: 345 SGNEEKLMALLTPL--NVNC-------------------------------HASDGRKST 371
++++++LL +VNC + D T
Sbjct: 601 LQCDKEMLSLLIKFGASVNCADHYHYTPLHYISRRGHLTMLQLLLQGKAEPNVVDDEGIT 780
Query: 372 PLHLAAGYNRVRIVQLLLQHGADVH---AKDKGGLVPLHNACSYGHYEVTEL 420
PL++A+ V IV +LLQ GA ++ A+D P+H AC GH EV L
Sbjct: 781 PLYIASCEGHVTIVNILLQSGAKIYMPCARD-----PVHAACKAGH-EVIAL 918
>02114
Length = 1072
Score = 87.8 bits (216), Expect = 3e-17, Method: Compositional matrix adjust.
Identities = 74/265 (27%), Positives = 114/265 (43%), Gaps = 4/265 (1%)
Frame = +1
Query: 683 RHSTPLHFAAGYNRVSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGAS 742
R TP H AA + ++ L ++G + AKD G PLH AC++GH + L+R G
Sbjct: 199 RGWTPAHIAAIRGQEGCIQALSNNGVSMSAKDTRGSTPLHLACAHGHSFCVQTLLRCGVD 378
Query: 743 VNVADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPLDLVK-EGDTDIQXXX 801
VN D +T +H ++ G+ ++L+K GA + +GNTP L EG
Sbjct: 379 VNSVDKTSWTSVHVSSYHGRLGCLQMLIKWGARYDDIDTNGNTPAHLAAMEGHLPCLKFL 558
Query: 802 XXXXXXXXXXXXXXXXRVQKLCTPENINCRDTQGRNSTPLHLAAGYNNLEVAEYL--LEH 859
+ C + R+ G TP LA + + EY+ ++H
Sbjct: 559 VS----------------SEGCPEHTLGARNDHGE--TPRDLAQQFYKENILEYIDHVQH 684
Query: 860 GADVNAQDKGGLIPLHNAASYGHVDIAALLIKYNTC-VNATDKWAFTPLHEAAQKGRTQL 918
D Q + P H AA G +D +L++ +N D T H AA +G +
Sbjct: 685 EMDHPEQAENLAFPAHMAAYNGELDHLRILVENGVVNINERDDKGNTLAHRAAGQGHLNI 864
Query: 919 CALLLAHGADPTMKNQEGQTPLDLA 943
L+ GAD + N G+T D+A
Sbjct: 865 LQWLVEMGADVEISNGAGETARDIA 939
Score = 78.6 bits (192), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 69/264 (26%), Positives = 122/264 (46%), Gaps = 3/264 (1%)
Frame = +1
Query: 215 RKSSPLHFAAGFGRKDVVEHLLQMGANVHARDDGGLIPLHNACSFGHAEVVSLLLCQGAD 274
R +P H AA G++ ++ L G ++ A+D G PLH AC+ GH+ V LL G D
Sbjct: 199 RGWTPAHIAAIRGQEGCIQALSNNGVSMSAKDTRGSTPLHLACAHGHSFCVQTLLRCGVD 378
Query: 275 PNARDNWNYTPLHEAAIKGKIDVCIVLLQHGADPNIRNTDGKSALDLADPSAKAVLTGEY 334
N+ D ++T +H ++ G++ +L++ GA + +T+G + P+ A + G
Sbjct: 379 VNSVDKTSWTSVHVSSYHGRLGCLQMLIKWGARYDDIDTNGNT------PAHLAAMEGHL 540
Query: 335 KKDELLEAARSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLL--LQHG 392
+ L ++ E L A + TP LA + + I++ + +QH
Sbjct: 541 PCLKFLVSSEGCPEHTLG-----------ARNDHGETPRDLAQQFYKENILEYIDHVQHE 687
Query: 393 ADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGAC-VNAMDLWQFTPLHEAASKNRVEVC 451
D + + P H A G + +L+++G +N D T H AA + + +
Sbjct: 688 MDHPEQAENLAFPAHMAAYNGELDHLRILVENGVVNINERDDKGNTLAHRAAGQGHLNIL 867
Query: 452 SLLLSHGADPTLVNCHGKSAVDMA 475
L+ GAD + N G++A D+A
Sbjct: 868 QWLVEMGADVEISNGAGETARDIA 939
Score = 68.6 bits (166), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 60/228 (26%), Positives = 105/228 (46%), Gaps = 15/228 (6%)
Frame = +1
Query: 524 TALHCAVASLHPKRKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAK 583
T LH A A H Q LLR G +VN +K T +HV++ +++L K GA+
Sbjct: 307 TPLHLACAHGHSFCVQT---LLRCGVDVNSVDKTSWTSVHVSSYHGRLGCLQMLIKWGAR 477
Query: 584 MNALDTLGQTALHRAALAGHLQTCRLLLS--------------YGSDPSIISLQGFTAAQ 629
+ +DT G T H AA+ GHL + L+S +G P ++ Q +
Sbjct: 478 YDDIDTNGNTPAHLAAMEGHLPCLKFLVSSEGCPEHTLGARNDHGETPRDLAQQFYKENI 657
Query: 630 MGNEAVQQILSE-STPIRTSDVDYRLLEASKAGDLETVKQLCSSQNVNCRDLEGRHSTPL 688
+ E + + E P + ++ + A+ G+L+ ++ L + VN + + + +T
Sbjct: 658 L--EYIDHVQHEMDHPEQAENLAFPAHMAAYNGELDHLRILVENGVVNINERDDKGNTLA 831
Query: 689 HFAAGYNRVSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELL 736
H AAG ++++++L+ GADV + G A + H +LL
Sbjct: 832 HRAAGQGHLNILQWLVEMGADVEISNGAGETARDIARRFAHLACVKLL 975
Score = 65.9 bits (159), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 63/254 (24%), Positives = 108/254 (42%), Gaps = 6/254 (2%)
Frame = +1
Query: 544 LLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTALHRAALAGH 603
L G +++ K+ TPLH+A H+ ++ L + G +N++D T++H ++ G
Sbjct: 259 LSNNGVSMSAKDTRGSTPLHLACAHGHSFCVQTLLRCGVDVNSVDKTSWTSVHVSSYHGR 438
Query: 604 LQTCRLLLSYGSDPSIISLQGFTAAQMGNEAVQQILSESTPIRTSDVDYRLLEASKAGDL 663
L ++L+ +G+ I G T A + A+ G L
Sbjct: 439 LGCLQMLIKWGARYDDIDTNGNTPAHL--------------------------AAMEGHL 540
Query: 664 ETVKQLCSSQNVNCRDLEGRHS---TPLHFAAGYNRVSVVEYLLH--HGADVHAKDKGGL 718
+K L SS+ L R+ TP A + + +++EY+ H H D + +
Sbjct: 541 PCLKFLVSSEGCPEHTLGARNDHGETPRDLAQQFYKENILEYIDHVQHEMDHPEQAENLA 720
Query: 719 VPLHNACSYGHYEVAELLVRHG-ASVNVADLWKFTPLHEAAAKGKYEICKLLLKHGADPT 777
P H A G + +LV +G ++N D T H AA +G I + L++ GAD
Sbjct: 721 FPAHMAAYNGELDHLRILVENGVVNINERDDKGNTLAHRAAGQGHLNILQWLVEMGADVE 900
Query: 778 KKNRDGNTPLDLVK 791
N G T D+ +
Sbjct: 901 ISNGAGETARDIAR 942
Score = 65.9 bits (159), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 65/251 (25%), Positives = 97/251 (38%), Gaps = 25/251 (9%)
Frame = +1
Query: 664 ETVKQLCSSQNVNCRDLEGRHSTPLHFAAGYNRVSVVEYLLHHGADVHAKDKGGLVPLHN 723
E Q S+ V+ + R STPLH A + V+ LL G DV++ DK +H
Sbjct: 241 EGCIQALSNNGVSMSAKDTRGSTPLHLACAHGHSFCVQTLLRCGVDVNSVDKTSWTSVHV 420
Query: 724 ACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAAAKGKYEICKLLLKHGADPT----KK 779
+ +G ++L++ GA + D TP H AA +G K L+ P +
Sbjct: 421 SSYHGRLGCLQMLIKWGARYDDIDTNGNTPAHLAAMEGHLPCLKFLVSSEGCPEHTLGAR 600
Query: 780 NRDGNTPLDLVKEGDTDIQXXXXXXXXXXXXXXXXXXXRVQKLCTPE------------- 826
N G TP DL ++ + + L P
Sbjct: 601 NDHGETPRDLAQQ----FYKENILEYIDHVQHEMDHPEQAENLAFPAHMAAYNGELDHLR 768
Query: 827 --------NINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAA 878
NIN RD +G +T H AAG +L + ++L+E GADV + G A
Sbjct: 769 ILVENGVVNINERDDKG--NTLAHRAAGQGHLNILQWLVEMGADVEISNGAGETARDIAR 942
Query: 879 SYGHVDIAALL 889
+ H+ LL
Sbjct: 943 RFAHLACVKLL 975
Score = 43.5 bits (101), Expect = 6e-04, Method: Compositional matrix adjust.
Identities = 26/67 (38%), Positives = 36/67 (53%), Gaps = 1/67 (1%)
Frame = +3
Query: 721 LHNACSYGHYEVAELLVRHGASVN-VADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKK 779
+H+A + E++V++GAS+N V D FTP+H A G E LL HGAD T
Sbjct: 12 IHDAVRHSDVLYLEVMVKNGASINEVEDRDNFTPVHTACNIGALECLHWLLWHGADATVT 191
Query: 780 NRDGNTP 786
+ G P
Sbjct: 192 HTXGLDP 212
Score = 39.3 bits (90), Expect = 0.011, Method: Compositional matrix adjust.
Identities = 22/64 (34%), Positives = 36/64 (56%), Gaps = 1/64 (1%)
Frame = +3
Query: 406 LHNACSYGHYEVTELLLKHGACVNAM-DLWQFTPLHEAASKNRVEVCSLLLSHGADPTLV 464
+H+A + E+++K+GA +N + D FTP+H A + +E LL HGAD T+
Sbjct: 12 IHDAVRHSDVLYLEVMVKNGASINEVEDRDNFTPVHTACNIGALECLHWLLWHGADATVT 191
Query: 465 NCHG 468
+ G
Sbjct: 192 HTXG 203
Score = 38.9 bits (89), Expect = 0.013, Method: Compositional matrix adjust.
Identities = 26/87 (29%), Positives = 44/87 (50%)
Frame = +1
Query: 189 ACRNGDVSRVKRLVDAANVNAKDMAGRKSSPLHFAAGFGRKDVVEHLLQMGANVHARDDG 248
A NG++ ++ LV+ VN + + ++ H AAG G ++++ L++MGA+V +
Sbjct: 736 AAYNGELDHLRILVENGVVNINERDDKGNTLAHRAAGQGHLNILQWLVEMGADVEISNGA 915
Query: 249 GLIPLHNACSFGHAEVVSLLLCQGADP 275
G A F H V LL G +P
Sbjct: 916 GETARDIARRFAHLACVKLL---GGEP 987
Score = 37.0 bits (84), Expect = 0.059, Method: Compositional matrix adjust.
Identities = 21/67 (31%), Positives = 33/67 (49%), Gaps = 1/67 (1%)
Frame = +3
Query: 874 LHNAASYGHVDIAALLIKYNTCVNAT-DKWAFTPLHEAAQKGRTQLCALLLAHGADPTMK 932
+H+A + V +++K +N D+ FTP+H A G + LL HGAD T+
Sbjct: 12 IHDAVRHSDVLYLEVMVKNGASINEVEDRDNFTPVHTACNIGALECLHWLLWHGADATVT 191
Query: 933 NQEGQTP 939
+ G P
Sbjct: 192 HTXGLDP 212
Score = 34.7 bits (78), Expect = 0.23, Method: Compositional matrix adjust.
Identities = 17/55 (30%), Positives = 33/55 (60%), Gaps = 1/55 (1%)
Frame = +3
Query: 373 LHLAAGYNRVRIVQLLLQHGADVH-AKDKGGLVPLHNACSYGHYEVTELLLKHGA 426
+H A ++ V +++++++GA ++ +D+ P+H AC+ G E LL HGA
Sbjct: 12 IHDAVRHSDVLYLEVMVKNGASINEVEDRDNFTPVHTACNIGALECLHWLLWHGA 176
Score = 34.7 bits (78), Expect = 0.24, Method: Compositional matrix adjust.
Identities = 19/67 (28%), Positives = 33/67 (49%), Gaps = 1/67 (1%)
Frame = +3
Query: 688 LHFAAGYNRVSVVEYLLHHGADVH-AKDKGGLVPLHNACSYGHYEVAELLVRHGASVNVA 746
+H A ++ V +E ++ +GA ++ +D+ P+H AC+ G E L+ HGA V
Sbjct: 12 IHDAVRHSDVLYLEVMVKNGASINEVEDRDNFTPVHTACNIGALECLHWLLWHGADATVT 191
Query: 747 DLWKFTP 753
P
Sbjct: 192 HTXGLDP 212
Score = 33.5 bits (75), Expect = 0.62, Method: Compositional matrix adjust.
Identities = 20/64 (31%), Positives = 32/64 (50%), Gaps = 1/64 (1%)
Frame = +3
Query: 253 LHNACSFGHAEVVSLLLCQGADPN-ARDNWNYTPLHEAAIKGKIDVCIVLLQHGADPNIR 311
+H+A + +++ GA N D N+TP+H A G ++ LL HGAD +
Sbjct: 12 IHDAVRHSDVLYLEVMVKNGASINEVEDRDNFTPVHTACNIGALECLHWLLWHGADATVT 191
Query: 312 NTDG 315
+T G
Sbjct: 192 HTXG 203
Score = 32.7 bits (73), Expect = 0.97, Method: Compositional matrix adjust.
Identities = 16/37 (43%), Positives = 18/37 (48%)
Frame = +3
Query: 837 NSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIP 873
N TP+H A LE +LL HGAD GL P
Sbjct: 102 NFTPVHTACNIGALECLHWLLWHGADATVTHTXGLDP 212
Score = 31.6 bits (70), Expect = 2.2, Method: Compositional matrix adjust.
Identities = 16/51 (31%), Positives = 28/51 (54%), Gaps = 1/51 (1%)
Frame = +3
Query: 542 ELLLRKGANVNE-KNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDTLG 591
E++++ GA++NE +++D TP+H A + + L HGA T G
Sbjct: 51 EVMVKNGASINEVEDRDNFTPVHTACNIGALECLHWLLWHGADATVTHTXG 203
Score = 29.6 bits (65), Expect = 9.0, Method: Compositional matrix adjust.
Identities = 15/44 (34%), Positives = 25/44 (56%), Gaps = 1/44 (2%)
Frame = +3
Query: 232 VEHLLQMGANVH-ARDDGGLIPLHNACSFGHAEVVSLLLCQGAD 274
+E +++ GA+++ D P+H AC+ G E + LL GAD
Sbjct: 48 LEVMVKNGASINEVEDRDNFTPVHTACNIGALECLHWLLWHGAD 179
>13462
Length = 1388
Score = 82.8 bits (203), Expect = 8e-16, Method: Compositional matrix adjust.
Identities = 75/258 (29%), Positives = 111/258 (43%), Gaps = 4/258 (1%)
Frame = +3
Query: 687 PLHFAAGYNR--VSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGASVN 744
PLH+A+ ++ + +V LL +GA + +D+ G LH ACS + +V LL+ G V
Sbjct: 186 PLHYASHHSNGNLGIVSMLLAYGAQPNVQDEDGNTALHLACSESNVDVVRLLLEWGGDVA 365
Query: 745 VADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPLDLVKEGDTDIQXXXXXX 804
VAD+ TPL A E+ LLL G+DP N PL++V
Sbjct: 366 VADIDNETPLVRACLANSVELVDLLLHAGSDP---NHSHGRPLEIV-------------- 494
Query: 805 XXXXXXXXXXXXXRVQKLCTPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVN 864
R L + + + Q +T L A+ +N L++ + L +G DVN
Sbjct: 495 ------------VRAPSLESLKLLIGAGAQVTGNTYLSFASEHNYLDMMKVLHNYGVDVN 638
Query: 865 AQDKGGLIPLHNAASYGHV--DIAALLIKYNTCVNATDKWAFTPLHEAAQKGRTQLCALL 922
+ GL LH+A D LL+ + + N TPLH A Q LL
Sbjct: 639 GTGRLGLTALHHACISQEATHDAVRLLLLWGSNPNLVTGTGDTPLHFACQTFAVSKVRLL 818
Query: 923 LAHGADPTMKNQEGQTPL 940
L +GAD + +PL
Sbjct: 819 LMYGADVNQIDGTHTSPL 872
Score = 76.3 bits (186), Expect = 8e-14, Method: Compositional matrix adjust.
Identities = 81/262 (30%), Positives = 123/262 (46%), Gaps = 21/262 (8%)
Frame = +3
Query: 219 PLHFAA--GFGRKDVVEHLLQMGANVHARDDGGLIPLHNACSFGHAEVVSLLLCQGADPN 276
PLH+A+ G +V LL GA + +D+ G LH ACS + +VV LLL G D
Sbjct: 186 PLHYASHHSNGNLGIVSMLLAYGAQPNVQDEDGNTALHLACSESNVDVVRLLLEWGGDVA 365
Query: 277 ARDNWNYTPLHEAAIKGKIDVCIVLLQHGADPNIRNTDGKSA-LDLADPSAKA--VLTG- 332
D N TPL A + +++ +LL G+DPN ++ G+ + + PS ++ +L G
Sbjct: 366 VADIDNETPLVRACLANSVELVDLLLHAGSDPN--HSHGRPLEIVVRAPSLESLKLLIGA 539
Query: 333 --EYKKDELLEAARSGNEEKLMALLTPLNVNCHASDGRKSTPLHLA-----AGYNRVRIV 385
+ + L A N +M +L V+ + + T LH A A ++ VR
Sbjct: 540 GAQVTGNTYLSFASEHNYLDMMKVLHNYGVDVNGTGRLGLTALHHACISQEATHDAVR-- 713
Query: 386 QLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASK 445
LLL G++ + G PLH AC LLL +GA VN +D +PL A +
Sbjct: 714 -LLLLWGSNPNLVTGTGDTPLHFACQTFAVSKVRLLLMYGADVNQIDGTHTSPLIAALTT 890
Query: 446 NR--------VEVCSLLLSHGA 459
R +++ LLL+ GA
Sbjct: 891 RRQPQNDASYLDLIRLLLAAGA 956
Score = 76.3 bits (186), Expect = 9e-14, Method: Compositional matrix adjust.
Identities = 83/262 (31%), Positives = 121/262 (46%), Gaps = 18/262 (6%)
Frame = +3
Query: 372 PLHLAAGYNR--VRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGACVN 429
PLH A+ ++ + IV +LL +GA + +D+ G LH ACS + +V LLL+ G V
Sbjct: 186 PLHYASHHSNGNLGIVSMLLAYGAQPNVQDEDGNTALHLACSESNVDVVRLLLEWGGDVA 365
Query: 430 AMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGK--SAVDMAPTPELRERLT-- 485
D+ TPL A N VE+ LLL G+DP + HG+ V AP+ E + L
Sbjct: 366 VADIDNETPLVRACLANSVELVDLLLHAGSDPN--HSHGRPLEIVVRAPSLESLKLLIGA 539
Query: 486 -YEFKGHSLLQAARE---ADLAKVKKTLALEIINFKQPQSHETALHCAVASLHPKRKQVT 541
+ G++ L A E D+ KV +++ + TALH A S V
Sbjct: 540 GAQVTGNTYLSFASEHNYLDMMKVLHNYGVDV--NGTGRLGLTALHHACISQEATHDAV- 710
Query: 542 ELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTALHRAAL- 600
LLL G+N N TPLH A + + +L +GA +N +D + L A
Sbjct: 711 RLLLLWGSNPNLVTGTGDTPLHFACQTFAVSKVRLLLMYGADVNQIDGTHTSPLIAALTT 890
Query: 601 -------AGHLQTCRLLLSYGS 615
A +L RLLL+ G+
Sbjct: 891 RRQPQNDASYLDLIRLLLAAGA 956
Score = 68.6 bits (166), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 74/270 (27%), Positives = 130/270 (48%), Gaps = 18/270 (6%)
Frame = +3
Query: 536 KRKQVTELLLRKGANVNEKNKDFMT--PLHVAAERAHND--VMEVLHKHGAKMNALDTLG 591
R + +LL++GA + + ++ PLH A+ ++ + ++ +L +GA+ N D G
Sbjct: 108 NRADLVPVLLQRGA-LPDLPSLYLNKRPLHYASHHSNGNLGIVSMLLAYGAQPNVQDEDG 284
Query: 592 QTALHRAALAGHLQTCRLLLSYGSDPSIISLQGFTAAQMGNEA--VQQILSESTPIRT-- 647
TALH A ++ RLLL +G D ++ A + NE V+ L+ S +
Sbjct: 285 NTALHLACSESNVDVVRLLLEWGGDVAV--------ADIDNETPLVRACLANSVELVDLL 440
Query: 648 ----SDVDY---RLLE-ASKAGDLETVKQLCSSQNVNCRDLEGRHSTPLHFAAGYNRVSV 699
SD ++ R LE +A LE++K L + + +T L FA+ +N + +
Sbjct: 441 LHAGSDPNHSHGRPLEIVVRAPSLESLKLLIGAGA------QVTGNTYLSFASEHNYLDM 602
Query: 700 VEYLLHHGADVHAKDKGGLVPLHNAC--SYGHYEVAELLVRHGASVNVADLWKFTPLHEA 757
++ L ++G DV+ + GL LH+AC ++ LL+ G++ N+ TPLH A
Sbjct: 603 MKVLHNYGVDVNGTGRLGLTALHHACISQEATHDAVRLLLLWGSNPNLVTGTGDTPLHFA 782
Query: 758 AAKGKYEICKLLLKHGADPTKKNRDGNTPL 787
+LLL +GAD + + +PL
Sbjct: 783 CQTFAVSKVRLLLMYGADVNQIDGTHTSPL 872
Score = 63.9 bits (154), Expect = 4e-10, Method: Compositional matrix adjust.
Identities = 66/258 (25%), Positives = 105/258 (40%), Gaps = 21/258 (8%)
Frame = +3
Query: 717 GLVPLHNACSYGHYEVAELLVRHGASVNVADLW-KFTPLHEAA--AKGKYEICKLLLKHG 773
GL L AC ++ +L++ GA ++ L+ PLH A+ + G I +LL +G
Sbjct: 75 GLTLLCVACKLNRADLVPVLLQRGALPDLPSLYLNKRPLHYASHHSNGNLGIVSMLLAYG 254
Query: 774 ADPTKKNRDGNTPLDLV-KEGDTDIQXXXXXXXXXXXXXXXXXXXRVQKLCTPENINCRD 832
A P ++ DGNT L L E + D+ + + C ++ D
Sbjct: 255 AQPNVQDEDGNTALHLACSESNVDVVRLLLEWGGDVAVADIDNETPLVRACLANSVELVD 434
Query: 833 -----------TQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYG 881
+ GR PL + +LE + L+ GA V L A+ +
Sbjct: 435 LLLHAGSDPNHSHGR---PLEIVVRAPSLESLKLLIGAGAQVTGNTY-----LSFASEHN 590
Query: 882 HVDIAALLIKYNTCVNATDKWAFTPLHEA--AQKGRTQLCALLLAHGADPTMKNQEGQTP 939
++D+ +L Y VN T + T LH A +Q+ LLL G++P + G TP
Sbjct: 591 YLDMMKVLHNYGVDVNGTGRLGLTALHHACISQEATHDAVRLLLLWGSNPNLVTGTGDTP 770
Query: 940 LDLA----TADDIRALLI 953
L A +R LL+
Sbjct: 771 LHFACQTFAVSKVRLLLM 824
Score = 56.2 bits (134), Expect = 8e-08, Method: Compositional matrix adjust.
Identities = 84/311 (27%), Positives = 124/311 (39%), Gaps = 40/311 (12%)
Frame = +3
Query: 192 NGDVSRVKRLVD-AANVNAKDMAGRKSSPLHFAAGFGRKDVVEHLLQMGANVHARDDGGL 250
NG++ V L+ A N +D G ++ LH A DVV LL+ G +V D
Sbjct: 213 NGNLGIVSMLLAYGAQPNVQDEDG--NTALHLACSESNVDVVRLLLEWGGDVAVADIDNE 386
Query: 251 IPLHNACSFGHAEVVSLLLCQGADPN--------------------------ARDNWNYT 284
PL AC E+V LLL G+DPN A+ N T
Sbjct: 387 TPLVRACLANSVELVDLLLHAGSDPNHSHGRPLEIVVRAPSLESLKLLIGAGAQVTGN-T 563
Query: 285 PLHEAAIKGKIDVCIVLLQHGADPNIRNTDGKSALDLADPSAKAVLTGEYKKDELLEAAR 344
L A+ +D+ VL +G D N G +AL A ++ E D +
Sbjct: 564 YLSFASEHNYLDMMKVLHNYGVDVNGTGRLGLTALH------HACISQEATHDAVRLLLL 725
Query: 345 SGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLV 404
G+ L+ G TPLH A V V+LLL +GADV+ D
Sbjct: 726 WGSNPNLVT-------------GTGDTPLHFACQTFAVSKVRLLLMYGADVNQIDGTHTS 866
Query: 405 PL----------HNACSYGHYEVTELLLKHGACVNAMDLWQFTPL---HEAASKNRVEVC 451
PL N SY ++ LLL GA +++ L + L ++++ ++ E+
Sbjct: 867 PLIAALTTRRQPQNDASY--LDLIRLLLAAGARLSSAVLERIKVLIVYLQSSATDKEELF 1040
Query: 452 SLLLSHGADPT 462
LL H ++P+
Sbjct: 1041QLLTKHTSEPS 1073
>19166
Length = 447
Score = 77.4 bits (189), Expect = 4e-14, Method: Compositional matrix adjust.
Identities = 45/122 (36%), Positives = 65/122 (53%), Gaps = 1/122 (0%)
Frame = +1
Query: 676 NCRDLEGRHSTPLHFAAGYNRVSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAEL 735
N R L G TPLH A NR+ VVE LL +GA + A + GL PLH + GH +
Sbjct: 40 NSRALNG--FTPLHIACKKNRIKVVELLLKYGASIDATTESGLTPLHVSSFMGHMNIVIY 213
Query: 736 LVRHGASVNVADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPLDLVKE-GD 794
L++H A + + T LH AA + +I ++LL++GA + R+ TPL + G+
Sbjct: 214 LIQHNAYPDTPTVRGETSLHLAARANQTDIIRILLRNGAAVDARAREQQTPLHIASRLGN 393
Query: 795 TD 796
D
Sbjct: 394 VD 399
Score = 76.3 bits (186), Expect = 8e-14, Method: Compositional matrix adjust.
Identities = 45/122 (36%), Positives = 69/122 (56%)
Frame = +1
Query: 823 CTPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGH 882
C P N R G TPLH+A N ++V E LL++GA ++A + GL PLH ++ GH
Sbjct: 31 CEP---NSRALNG--FTPLHIACKKNRIKVVELLLKYGASIDATTESGLTPLHVSSFMGH 195
Query: 883 VDIAALLIKYNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTPLDL 942
++I LI++N + T LH AA+ +T + +LL +GA + +E QTPL +
Sbjct: 196 MNIVIYLIQHNAYPDTPTVRGETSLHLAARANQTDIIRILLRNGAAVDARAREQQTPLHI 375
Query: 943 AT 944
A+
Sbjct: 376 AS 381
Score = 69.7 bits (169), Expect = 7e-12, Method: Compositional matrix adjust.
Identities = 34/89 (38%), Positives = 54/89 (60%)
Frame = +1
Query: 371 TPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGACVNA 430
TPLH+A NR+++V+LLL++GA + A + GL PLH + GH + L++H A +
Sbjct: 64 TPLHIACKKNRIKVVELLLKYGASIDATTESGLTPLHVSSFMGHMNIVIYLIQHNAYPDT 243
Query: 431 MDLWQFTPLHEAASKNRVEVCSLLLSHGA 459
+ T LH AA N+ ++ +LL +GA
Sbjct: 244 PTVRGETSLHLAARANQTDIIRILLRNGA 330
Score = 69.7 bits (169), Expect = 8e-12, Method: Compositional matrix adjust.
Identities = 55/166 (33%), Positives = 75/166 (45%), Gaps = 3/166 (1%)
Frame = +1
Query: 235 LLQMGANVHARDDGGLIPLHNACSFGHAEVVSLLLCQGADPNARDNWNYTPLHEAAIKGK 294
LL ++R G PLH AC +VV LLL GA +A TPLH ++ G
Sbjct: 16 LLDRKCEPNSRALNGFTPLHIACKKNRIKVVELLLKYGASIDATTESGLTPLHVSSFMGH 195
Query: 295 IDVCIVLLQHGADPNIRNTDGKSALDLADPSAKAVLTGEYKKDELLEAARSGNEEKLMAL 354
+++ I L+QH A P+ G+++L L AAR+ + + L
Sbjct: 196 MNIVIYLIQHNAYPDTPTVRGETSLHL--------------------AARANQTDIIRIL 315
Query: 355 LTPLNVNCHASDGR---KSTPLHLAAGYNRVRIVQLLLQHGADVHA 397
L N A D R + TPLH+A+ V V LLLQHGA A
Sbjct: 316 LR----NGAAVDARAREQQTPLHIASRLGNVDNVVLLLQHGASADA 441
Score = 62.8 bits (151), Expect = 9e-10, Method: Compositional matrix adjust.
Identities = 37/105 (35%), Positives = 56/105 (53%)
Frame = +1
Query: 218 SPLHFAAGFGRKDVVEHLLQMGANVHARDDGGLIPLHNACSFGHAEVVSLLLCQGADPNA 277
+PLH A R VVE LL+ GA++ A + GL PLH + GH +V L+ A P+
Sbjct: 64 TPLHIACKKNRIKVVELLLKYGASIDATTESGLTPLHVSSFMGHMNIVIYLIQHNAYPDT 243
Query: 278 RDNWNYTPLHEAAIKGKIDVCIVLLQHGADPNIRNTDGKSALDLA 322
T LH AA + D+ +LL++GA + R + ++ L +A
Sbjct: 244 PTVRGETSLHLAARANQTDIIRILLRNGAAVDARAREQQTPLHIA 378
Score = 62.4 bits (150), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 50/164 (30%), Positives = 76/164 (46%)
Frame = +1
Query: 267 LLLCQGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGADPNIRNTDGKSALDLADPSA 326
LLL + +PN+R +TPLH A K +I V +LL++GA + G + L ++
Sbjct: 13 LLLDRKCEPNSRALNGFTPLHIACKKNRIKVVELLLKYGASIDATTESGLTPLHVSS--- 183
Query: 327 KAVLTGEYKKDELLEAARSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQ 386
G ++ L N R T LHLAA N+ I++
Sbjct: 184 ---FMGHMN---------------IVIYLIQHNAYPDTPTVRGETSLHLAARANQTDIIR 309
Query: 387 LLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGACVNA 430
+LL++GA V A+ + PLH A G+ + LLL+HGA +A
Sbjct: 310 ILLRNGAAVDARAREQQTPLHIASRLGNVDNVVLLLQHGASADA 441
Score = 61.6 bits (148), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 48/167 (28%), Positives = 73/167 (43%), Gaps = 2/167 (1%)
Frame = +1
Query: 701 EYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAAAK 760
+ LL + +++ G PLH AC +V ELL+++GAS++ TPLH ++
Sbjct: 10 KLLLDRKCEPNSRALNGFTPLHIACKKNRIKVVELLLKYGASIDATTESGLTPLHVSSFM 189
Query: 761 GKYEICKLLLKHGADPTKKNRDGNTPLDL-VKEGDTDIQXXXXXXXXXXXXXXXXXXXRV 819
G I L++H A P G T L L + TDI +
Sbjct: 190 GHMNIVIYLIQHNAYPDTPTVRGETSLHLAARANQTDI---------------------I 306
Query: 820 QKLCTPENINCRDTQGR-NSTPLHLAAGYNNLEVAEYLLEHGADVNA 865
+ L N D + R TPLH+A+ N++ LL+HGA +A
Sbjct: 307 RILL--RNGAAVDARAREQQTPLHIASRLGNVDNVVLLLQHGASADA 441
Score = 60.8 bits (146), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 51/170 (30%), Positives = 75/170 (44%), Gaps = 1/170 (0%)
Frame = +1
Query: 731 EVAELLVRHGASVNVADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPLDLV 790
+ A+LL+ N L FTPLH A K + ++ +LLLK+GA G TPL +
Sbjct: 1 KTAKLLLDRKCEPNSRALNGFTPLHIACKKNRIKVVELLLKYGASIDATTESGLTPLHVS 180
Query: 791 K-EGDTDIQXXXXXXXXXXXXXXXXXXXRVQKLCTPENINCRDTQGRNSTPLHLAAGYNN 849
G +I +Q P+ R T LHLAA N
Sbjct: 181 SFMGHMNIVIYL-----------------IQHNAYPDTPTVR-----GETSLHLAARANQ 294
Query: 850 LEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAALLIKYNTCVNAT 899
++ LL +GA V+A+ + PLH A+ G+VD LL+++ +AT
Sbjct: 295 TDIIRILLRNGAAVDARAREQQTPLHIASRLGNVDNVVLLLQHGASADAT 444
Score = 59.7 bits (143), Expect = 8e-09, Method: Compositional matrix adjust.
Identities = 47/204 (23%), Positives = 82/204 (40%)
Frame = +1
Query: 383 RIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEA 442
+ +LLL + +++ G PLH AC +V ELLLK+GA ++A TPLH +
Sbjct: 1 KTAKLLLDRKCEPNSRALNGFTPLHIACKKNRIKVVELLLKYGASIDATTESGLTPLHVS 180
Query: 443 ASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMAPTPELRERLTYEFKGHSLLQAAREADL 502
+ + + L+ H A P G++++ +A A + D+
Sbjct: 181 SFMGHMNIVIYLIQHNAYPDTPTVRGETSLHLAAR-------------------ANQTDI 303
Query: 503 AKVKKTLALEIINFKQPQSHETALHCAVASLHPKRKQVTELLLRKGANVNEKNKDFMTPL 562
++ LLR GA V+ + ++ TPL
Sbjct: 304 IRI--------------------------------------LLRNGAAVDARAREQQTPL 369
Query: 563 HVAAERAHNDVMEVLHKHGAKMNA 586
H+A+ + D + +L +HGA +A
Sbjct: 370 HIASRLGNVDNVVLLLQHGASADA 441
Score = 58.9 bits (141), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 47/174 (27%), Positives = 75/174 (43%)
Frame = +1
Query: 539 QVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTALHRA 598
+ +LLL + N + + TPLH+A ++ V+E+L K+GA ++A G T LH +
Sbjct: 1 KTAKLLLDRKCEPNSRALNGFTPLHIACKKNRIKVVELLLKYGASIDATTESGLTPLHVS 180
Query: 599 ALAGHLQTCRLLLSYGSDPSIISLQGFTAAQMGNEAVQQILSESTPIRTSDVDYRLLEAS 658
+ GH+ L+ + + P +++G T+ + A Q +D+ LL
Sbjct: 181 SFMGHMNIVIYLIQHNAYPDTPTVRGETSLHLAARANQ-----------TDIIRILLRNG 327
Query: 659 KAGDLETVKQLCSSQNVNCRDLEGRHSTPLHFAAGYNRVSVVEYLLHHGADVHA 712
A D +Q TPLH A+ V V LL HGA A
Sbjct: 328 AAVDARAREQ----------------QTPLHIASRLGNVDNVVLLLQHGASADA 441
Score = 57.8 bits (138), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 34/106 (32%), Positives = 51/106 (48%), Gaps = 4/106 (3%)
Frame = +1
Query: 851 EVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAALLIKYNTCVNATDKWAFTPLHEA 910
+ A+ LL+ + N++ G PLH A + + LL+KY ++AT + TPLH +
Sbjct: 1 KTAKLLLDRKCEPNSRALNGFTPLHIACKKNRIKVVELLLKYGASIDATTESGLTPLHVS 180
Query: 911 AQKGRTQLCALLLAHGADPTMKNQEGQTPLDLAT----ADDIRALL 952
+ G + L+ H A P G+T L LA D IR LL
Sbjct: 181 SFMGHMNIVIYLIQHNAYPDTPTVRGETSLHLAARANQTDIIRILL 318
Score = 52.0 bits (123), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 30/89 (33%), Positives = 47/89 (52%)
Frame = +1
Query: 686 TPLHFAAGYNRVSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGASVNV 745
TPLH ++ +++V YL+ H A G LH A ++ +L+R+GA+V+
Sbjct: 163 TPLHVSSFMGHMNIVIYLIQHNAYPDTPTVRGETSLHLAARANQTDIIRILLRNGAAVDA 342
Query: 746 ADLWKFTPLHEAAAKGKYEICKLLLKHGA 774
+ TPLH A+ G + LLL+HGA
Sbjct: 343 RAREQQTPLHIASRLGNVDNVVLLLQHGA 429
Score = 51.6 bits (122), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 32/92 (34%), Positives = 50/92 (54%)
Frame = +1
Query: 524 TALHCAVASLHPKRKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAK 583
T LH A R +V ELLL+ GA+++ + +TPLHV++ H +++ L +H A
Sbjct: 64 TPLHIACKK---NRIKVVELLLKYGASIDATTESGLTPLHVSSFMGHMNIVIYLIQHNAY 234
Query: 584 MNALDTLGQTALHRAALAGHLQTCRLLLSYGS 615
+ G+T+LH AA A R+LL G+
Sbjct: 235 PDTPTVRGETSLHLAARANQTDIIRILLRNGA 330
Score = 46.6 bits (109), Expect = 7e-05, Method: Compositional matrix adjust.
Identities = 42/154 (27%), Positives = 64/154 (41%)
Frame = +1
Query: 591 GQTALHRAALAGHLQTCRLLLSYGSDPSIISLQGFTAAQMGNEAVQQILSESTPIRTSDV 650
G T LH A ++ LLL YG+ + G T L S+ + ++
Sbjct: 58 GFTPLHIACKKNRIKVVELLLKYGASIDATTESGLTP-----------LHVSSFMGHMNI 204
Query: 651 DYRLLEASKAGDLETVKQLCSSQNVNCRDLEGRHSTPLHFAAGYNRVSVVEYLLHHGADV 710
L++ + D TV R T LH AA N+ ++ LL +GA V
Sbjct: 205 VIYLIQHNAYPDTPTV----------------RGETSLHLAARANQTDIIRILLRNGAAV 336
Query: 711 HAKDKGGLVPLHNACSYGHYEVAELLVRHGASVN 744
A+ + PLH A G+ + LL++HGAS +
Sbjct: 337 DARAREQQTPLHIASRLGNVDNVVLLLQHGASAD 438
Score = 41.6 bits (96), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 25/63 (39%), Positives = 33/63 (52%)
Frame = +1
Query: 215 RKSSPLHFAAGFGRKDVVEHLLQMGANVHARDDGGLIPLHNACSFGHAEVVSLLLCQGAD 274
R + LH AA + D++ LL+ GA V AR PLH A G+ + V LLL GA
Sbjct: 253 RGETSLHLAARANQTDIIRILLRNGAAVDARAREQQTPLHIASRLGNVDNVVLLLQHGAS 432
Query: 275 PNA 277
+A
Sbjct: 433 ADA 441
>05924
Length = 704
Score = 75.9 bits (185), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 63/208 (30%), Positives = 93/208 (44%), Gaps = 2/208 (0%)
Frame = +1
Query: 730 YEVAELLVRHGASVNVADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPLDL 789
++ + LV+ G VN + T LHEA + ++ ++L+K GA+ N+DG T L L
Sbjct: 4 HKAVQRLVKGGVDVNARFWYDSTLLHEAVSMASEDLVQMLIKAGANANSTNQDGRTALHL 183
Query: 790 V-KEGDTDIQXXXXXXXXXXXXXXXXXXXRVQKLCTP-ENINCRDTQGRNSTPLHLAAGY 847
+ G T+I VQ L ++N R G+ T LH+A
Sbjct: 184 ACRGGYTNI---------------------VQILIAAGTDVNRRTVDGK--TCLHVAVWR 294
Query: 848 NNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAALLIKYNTCVNATDKWAFTPL 907
+ EV L+ GADVN D G PL+ AA + I +L+ VN K +TPL
Sbjct: 295 GHTEVVVKLVNAGADVNIPDSVGCSPLYWAARSNYTAILTVLVNAGAKVNYRVKSKWTPL 474
Query: 908 HEAAQKGRTQLCALLLAHGADPTMKNQE 935
H A G + LL GA+ + Q+
Sbjct: 475 HAALHLGHMGVVRYLLLQGAETNITVQD 558
Score = 70.1 bits (170), Expect = 6e-12, Method: Compositional matrix adjust.
Identities = 64/213 (30%), Positives = 95/213 (44%), Gaps = 1/213 (0%)
Frame = +1
Query: 263 EVVSLLLCQGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGADPNIRNTDGKSALDLA 322
+ V L+ G D NAR ++ T LHEA D+ +L++ GA+ N N DG++AL L
Sbjct: 7 KAVQRLVKGGVDVNARFWYDSTLLHEAVSMASEDLVQMLIKAGANANSTNQDGRTALHL- 183
Query: 323 DPSAKAVLTGEYKKDELLEAARSGNEEKLMALLTP-LNVNCHASDGRKSTPLHLAAGYNR 381
A R G + L+ +VN DG+ T LH+A
Sbjct: 184 -------------------ACRGGYTNIVQILIAAGTDVNRRTVDGK--TCLHVAVWRGH 300
Query: 382 VRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHE 441
+V L+ GADV+ D G PL+ A + + +L+ GA VN ++TPLH
Sbjct: 301 TEVVVKLVNAGADVNIPDSVGCSPLYWAARSNYTAILTVLVNAGAKVNYRVKSKWTPLHA 480
Query: 442 AASKNRVEVCSLLLSHGADPTLVNCHGKSAVDM 474
A + V LL GA+ T + K+ V +
Sbjct: 481 ALHLGHMGVVRYLLLQGAE-TNITVQDKTVVSL 576
Score = 68.6 bits (166), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 57/208 (27%), Positives = 96/208 (46%), Gaps = 1/208 (0%)
Frame = +1
Query: 539 QVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTALHRA 598
+ + L++ G +VN + T LH A A D++++L K GA N+ + G+TALH A
Sbjct: 7 KAVQRLVKGGVDVNARFWYDSTLLHEAVSMASEDLVQMLIKAGANANSTNQDGRTALHLA 186
Query: 599 ALAGHLQTCRLLLSYGSDPSIISLQGFTAAQMGNEAVQQILSESTPIRTSDVDYRLLEAS 658
G+ ++L++ G+D + ++ G T + A
Sbjct: 187 CRGGYTNIVQILIAAGTDVNRRTVDGKTCLHV--------------------------AV 288
Query: 659 KAGDLETVKQLCSS-QNVNCRDLEGRHSTPLHFAAGYNRVSVVEYLLHHGADVHAKDKGG 717
G E V +L ++ +VN D G +PL++AA N +++ L++ GA V+ + K
Sbjct: 289 WRGHTEVVVKLVNAGADVNIPDSVG--CSPLYWAARSNYTAILTVLVNAGAKVNYRVKSK 462
Query: 718 LVPLHNACSYGHYEVAELLVRHGASVNV 745
PLH A GH V L+ GA N+
Sbjct: 463 WTPLHAALHLGHMGVVRYLLLQGAETNI 546
Score = 61.6 bits (148), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 44/127 (34%), Positives = 66/127 (51%), Gaps = 1/127 (0%)
Frame = +1
Query: 189 ACRNGDVSRVKRLVDA-ANVNAKDMAGRKSSPLHFAAGFGRKDVVEHLLQMGANVHARDD 247
ACR G + V+ L+ A +VN + + G+ + LH A G +VV L+ GA+V+ D
Sbjct: 184 ACRGGYTNIVQILIAAGTDVNRRTVDGK--TCLHVAVWRGHTEVVVKLVNAGADVNIPDS 357
Query: 248 GGLIPLHNACSFGHAEVVSLLLCQGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGAD 307
G PL+ A + ++++L+ GA N R +TPLH A G + V LL GA+
Sbjct: 358 VGCSPLYWAARSNYTAILTVLVNAGAKVNYRVKSKWTPLHAALHLGHMGVVRYLLLQGAE 537
Query: 308 PNIRNTD 314
NI D
Sbjct: 538 TNITVQD 558
Score = 57.4 bits (137), Expect = 4e-08, Method: Compositional matrix adjust.
Identities = 42/115 (36%), Positives = 59/115 (51%), Gaps = 1/115 (0%)
Frame = +1
Query: 198 VKRLVDA-ANVNAKDMAGRKSSPLHFAAGFGRKDVVEHLLQMGANVHARDDGGLIPLHNA 256
V+ L+ A AN N+ + GR + LH A G ++V+ L+ G +V+ R G LH A
Sbjct: 112 VQMLIKAGANANSTNQDGR--TALHLACRGGYTNIVQILIAAGTDVNRRTVDGKTCLHVA 285
Query: 257 CSFGHAEVVSLLLCQGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGADPNIR 311
GH EVV L+ GAD N D+ +PL+ AA + VL+ GA N R
Sbjct: 286 VWRGHTEVVVKLVNAGADVNIPDSVGCSPLYWAARSNYTAILTVLVNAGAKVNYR 450
Score = 56.6 bits (135), Expect = 6e-08, Method: Compositional matrix adjust.
Identities = 56/205 (27%), Positives = 90/205 (43%)
Frame = +1
Query: 415 YEVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDM 474
++ + L+K G VNA + T LHEA S ++ +L+ GA+ N G++A+ +
Sbjct: 4 HKAVQRLVKGGVDVNARFWYDSTLLHEAVSMASEDLVQMLIKAGANANSTNQDGRTALHL 183
Query: 475 APTPELRERLTYEFKGHSLLQAAREADLAKVKKTLALEIINFKQPQSHETALHCAVASLH 534
A R Y L+ A + + ++ +T LH AV H
Sbjct: 184 AC------RGGYTNIVQILIAAGTDVN---------------RRTVDGKTCLHVAVWRGH 300
Query: 535 PKRKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTA 594
+V L+ GA+VN + +PL+ AA + ++ VL GAK+N T
Sbjct: 301 T---EVVVKLVNAGADVNIPDSVGCSPLYWAARSNYTAILTVLVNAGAKVNYRVKSKWTP 471
Query: 595 LHRAALAGHLQTCRLLLSYGSDPSI 619
LH A GH+ R LL G++ +I
Sbjct: 472 LHAALHLGHMGVVRYLLLQGAETNI 546
Score = 56.2 bits (134), Expect = 9e-08, Method: Compositional matrix adjust.
Identities = 54/199 (27%), Positives = 88/199 (44%), Gaps = 6/199 (3%)
Frame = +1
Query: 523 ETALHCAVASLHPKRKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGA 582
T LH AV+ + + ++L++ GAN N N+D T LH+A + +++++L G
Sbjct: 67 STLLHEAVS---MASEDLVQMLIKAGANANSTNQDGRTALHLACRGGYTNIVQILIAAGT 237
Query: 583 KMNALDTLGQTALHRAALAGHLQTCRLLLSYGSDPSIISLQG----FTAAQMGNEAVQQI 638
+N G+T LH A GH + L++ G+D +I G + AA+ A+ +
Sbjct: 238 DVNRRTVDGKTCLHVAVWRGHTEVVVKLVNAGADVNIPDSVGCSPLYWAARSNYTAILTV 417
Query: 639 LSESTPIRTSDVDYRLLEASKAGDLETVKQLCSSQNVNCRDLEGRHSTPLHFAAGYNRVS 698
L + + V+YR+ SK TPLH A +
Sbjct: 418 LVNA----GAKVNYRV--KSK-------------------------WTPLHAALHLGHMG 504
Query: 699 VVEYLLHHGA--DVHAKDK 715
VV YLL GA ++ +DK
Sbjct: 505 VVRYLLLQGAETNITVQDK 561
Score = 54.7 bits (130), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 44/135 (32%), Positives = 62/135 (45%), Gaps = 1/135 (0%)
Frame = +1
Query: 654 LLEASKAGDLETVKQLCSS-QNVNCRDLEGRHSTPLHFAAGYNRVSVVEYLLHHGADVHA 712
L EA + V+ L + N N + +GR T LH A ++V+ L+ G DV+
Sbjct: 76 LHEAVSMASEDLVQMLIKAGANANSTNQDGR--TALHLACRGGYTNIVQILIAAGTDVNR 249
Query: 713 KDKGGLVPLHNACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAAAKGKYEICKLLLKH 772
+ G LH A GH EV LV GA VN+ D +PL+ AA I +L+
Sbjct: 250 RTVDGKTCLHVAVWRGHTEVVVKLVNAGADVNIPDSVGCSPLYWAARSNYTAILTVLVNA 429
Query: 773 GADPTKKNRDGNTPL 787
GA + + TPL
Sbjct: 430 GAKVNYRVKSKWTPL 474
Score = 53.1 bits (126), Expect = 7e-07, Method: Compositional matrix adjust.
Identities = 38/116 (32%), Positives = 54/116 (46%), Gaps = 2/116 (1%)
Frame = +1
Query: 827 NINCRDTQGRNSTPLHLA--AGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVD 884
N N + GR T LHLA GY N + + L+ G DVN + G LH A GH +
Sbjct: 139 NANSTNQDGR--TALHLACRGGYTN--IVQILIAAGTDVNRRTVDGKTCLHVAVWRGHTE 306
Query: 885 IAALLIKYNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTPL 940
+ L+ VN D +PL+ AA+ T + +L+ GA + + TPL
Sbjct: 307 VVVKLVNAGADVNIPDSVGCSPLYWAARSNYTAILTVLVNAGAKVNYRVKSKWTPL 474
Score = 35.0 bits (79), Expect = 0.18, Method: Compositional matrix adjust.
Identities = 21/55 (38%), Positives = 28/55 (50%)
Frame = +1
Query: 889 LIKYNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTPLDLA 943
L+K VNA + T LHEA L +L+ GA+ NQ+G+T L LA
Sbjct: 22 LVKGGVDVNARFWYDSTLLHEAVSMASEDLVQMLIKAGANANSTNQDGRTALHLA 186
>21532
Length = 460
Score = 70.5 bits (171), Expect = 5e-12, Method: Compositional matrix adjust.
Identities = 39/104 (37%), Positives = 56/104 (53%), Gaps = 7/104 (6%)
Frame = -1
Query: 696 RVSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGAS-------VNVADL 748
V ++ LL HGADV+ +D G P NAC G+ + L+ G S +NV D
Sbjct: 460 NVPIINTLLSHGADVNIRDNTGCTPFANACCLGNLAAVKALLTPGESPSWSKPMINVRDN 281
Query: 749 WKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPLDLVKE 792
+ TPLH A+ +G I +LL++H AD KN G+ PL L ++
Sbjct: 280 SQNTPLHLASQEGHTAIVELLVEHKADLAAKNDSGHNPLSLARQ 149
Score = 64.3 bits (155), Expect = 3e-10, Method: Compositional matrix adjust.
Identities = 40/102 (39%), Positives = 52/102 (50%), Gaps = 7/102 (6%)
Frame = -1
Query: 849 NLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHV-DIAALLIKYNT------CVNATDK 901
N+ + LL HGADVN +D G P NA G++ + ALL + +N D
Sbjct: 460 NVPIINTLLSHGADVNIRDNTGCTPFANACCLGNLAAVKALLTPGESPSWSKPMINVRDN 281
Query: 902 WAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTPLDLA 943
TPLH A+Q+G T + LL+ H AD KN G PL LA
Sbjct: 280 SQNTPLHLASQEGHTAIVELLVEHKADLAAKNDSGHNPLSLA 155
Score = 62.8 bits (151), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 37/99 (37%), Positives = 51/99 (51%), Gaps = 7/99 (7%)
Frame = -1
Query: 231 VVEHLLQMGANVHARDDGGLIPLHNACSFGHAEVVSLLLCQGADP-------NARDNWNY 283
++ LL GA+V+ RD+ G P NAC G+ V LL G P N RDN
Sbjct: 451 IINTLLSHGADVNIRDNTGCTPFANACCLGNLAAVKALLTPGESPSWSKPMINVRDNSQN 272
Query: 284 TPLHEAAIKGKIDVCIVLLQHGADPNIRNTDGKSALDLA 322
TPLH A+ +G + +L++H AD +N G + L LA
Sbjct: 271 TPLHLASQEGHTAIVELLVEHKADLAAKNDSGHNPLSLA 155
Score = 57.0 bits (136), Expect = 5e-08, Method: Compositional matrix adjust.
Identities = 35/102 (34%), Positives = 48/102 (47%), Gaps = 7/102 (6%)
Frame = -1
Query: 381 RVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGAC-------VNAMDL 433
V I+ LL HGADV+ +D G P NAC G+ + LL G +N D
Sbjct: 460 NVPIINTLLSHGADVNIRDNTGCTPFANACCLGNLAAVKALLTPGESPSWSKPMINVRDN 281
Query: 434 WQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMA 475
Q TPLH A+ + + LL+ H AD N G + + +A
Sbjct: 280 SQNTPLHLASQEGHTAIVELLVEHKADLAAKNDSGHNPLSLA 155
Score = 55.1 bits (131), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 45/129 (34%), Positives = 60/129 (46%), Gaps = 1/129 (0%)
Frame = -1
Query: 294 KIDVCIVLLQHGADPNIRNTDGKSALDLADPSAKAVLTGEYKK-DELLEAARSGNEEKLM 352
+ + LL HGAD NIR+ G + P A A G LL S + K M
Sbjct: 460 NVPIINTLLSHGADVNIRDNTGCT------PFANACCLGNLAAVKALLTPGESPSWSKPM 299
Query: 353 ALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSY 412
+NV D ++TPLHLA+ IV+LL++H AD+ AK+ G PL A Y
Sbjct: 298 -----INV----RDNSQNTPLHLASQEGHTAIVELLVEHKADLAAKNDSGHNPLSLARQY 146
Query: 413 GHYEVTELL 421
H V +L
Sbjct: 145 KHENVVAVL 119
Score = 45.4 bits (106), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 42/158 (26%), Positives = 59/158 (37%)
Frame = -1
Query: 732 VAELLVRHGASVNVADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPLDLVK 791
+ L+ HGA VN+ D TP A G K LL G P+ + P+
Sbjct: 451 IINTLLSHGADVNIRDNTGCTPFANACCLGNLAAVKALLTPGESPS-----WSKPM---- 299
Query: 792 EGDTDIQXXXXXXXXXXXXXXXXXXXRVQKLCTPENINCRDTQGRNSTPLHLAAGYNNLE 851
IN RD +TPLHLA+ +
Sbjct: 298 ------------------------------------INVRD--NSQNTPLHLASQEGHTA 233
Query: 852 VAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAALL 889
+ E L+EH AD+ A++ G PL A Y H ++ A+L
Sbjct: 232 IVELLVEHKADLAAKNDSGHNPLSLARQYKHENVVAVL 119
Score = 37.4 bits (85), Expect = 0.038, Method: Compositional matrix adjust.
Identities = 34/110 (30%), Positives = 49/110 (44%), Gaps = 7/110 (6%)
Frame = -1
Query: 201 LVDAANVNAKDMAGRKSSPLHFAAGFGRKDVVEHLLQMGAN-------VHARDDGGLIPL 253
L A+VN +D G +P A G V+ LL G + ++ RD+ PL
Sbjct: 436 LSHGADVNIRDNTG--CTPFANACCLGNLAAVKALLTPGESPSWSKPMINVRDNSQNTPL 263
Query: 254 HNACSFGHAEVVSLLLCQGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQ 303
H A GH +V LL+ AD A+++ + PL A +V VL Q
Sbjct: 262 HLASQEGHTAIVELLVEHKADLAAKNDSGHNPLSLARQYKHENVVAVLQQ 113
Score = 36.6 bits (83), Expect = 0.062, Method: Compositional matrix adjust.
Identities = 30/103 (29%), Positives = 43/103 (41%), Gaps = 7/103 (6%)
Frame = -1
Query: 827 NINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGAD-------VNAQDKGGLIPLHNAAS 879
++N RD G TP A NL + LL G +N +D PLH A+
Sbjct: 421 DVNIRDNTG--CTPFANACCLGNLAAVKALLTPGESPSWSKPMINVRDNSQNTPLHLASQ 248
Query: 880 YGHVDIAALLIKYNTCVNATDKWAFTPLHEAAQKGRTQLCALL 922
GH I LL+++ + A + PL A Q + A+L
Sbjct: 247 EGHTAIVELLVEHKADLAAKNDSGHNPLSLARQYKHENVVAVL 119
Score = 30.8 bits (68), Expect = 4.3, Method: Compositional matrix adjust.
Identities = 15/48 (31%), Positives = 27/48 (56%)
Frame = -1
Query: 551 VNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTALHRA 598
+N ++ TPLH+A++ H ++E+L +H A + A + G L A
Sbjct: 298 INVRDNSQNTPLHLASQEGHTAIVELLVEHKADLAAKNDSGHNPLSLA 155
>16561
Length = 2029
Score = 66.6 bits (161), Expect = 6e-11, Method: Compositional matrix adjust.
Identities = 76/282 (26%), Positives = 121/282 (42%), Gaps = 42/282 (14%)
Frame = -3
Query: 556 KDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTALHRAALAGHLQTCRLLLSYGS 615
+D T LH +A DV+++L GAK+NAL+ G + LH A H++ +LL+ G
Sbjct: 2018 RDGDTALHYSAFGNQPDVLQLLLSKGAKINALNNGGCSTLHVAVNKQHIKCVHVLLNXGC 1839
Query: 616 DPSIISLQGFTAAQ--MGNEAVQQILSES------TPIRTSDVDYRLLEASKAGDLETVK 667
D + G TA +G AV+ + S S +P TS AS + ++ +
Sbjct: 1838 DVNXQDAYGDTALHDAIGKRAVKSLTSLSITLALISPSETS-------VASMSSIMQP*R 1680
Query: 668 QLCSSQNVNCRDLE-----GRHSTPLHFAAG--YNRVSVVEYLLHHGADVHAKDKGGLVP 720
+C ++ +C +++ G+ LHF + + ++LL + A+V ++ P
Sbjct: 1679 AMCLPRSASCTNVDRLWT*GKMMGFLHFTWLL*MDTRMLQQHLLRNRAEVDIRNNRQQTP 1500
Query: 721 LHNACSYGHYEVAELLVRHGASVNVADLWKFTPLH------------------------- 755
L A S GH + ELLV A +NV+D T LH
Sbjct: 1499 LLLAVSQGHSSLIELLVHAQADINVSDEDGDTCLHLALMRQTVATEDSSRMLDSIRSQLG 1320
Query: 756 --EAAAKGKYEICKLLLKHGADPTKKNRDGNTPLDLVKEGDT 795
E A+ I L + GA T N+ G PLD+ + T
Sbjct: 1319 MGEDEAQTGAAIACYLAQQGASLTACNQQGKXPLDVTTDTRT 1194
Score = 59.7 bits (143), Expect = 8e-09, Method: Compositional matrix adjust.
Identities = 61/231 (26%), Positives = 100/231 (43%), Gaps = 1/231 (0%)
Frame = -3
Query: 371 TPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGACVNA 430
T LH +A N+ ++QLLL GA ++A + GG LH A + H + +LL G VN
Sbjct: 2006 TALHYSAFGNQPDVLQLLLSKGAKINALNNGGCSTLHVAVNKQHIKCVHVLLNXGCDVNX 1827
Query: 431 MDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMAPTPELRERLTYEFKG 490
D + T LH+A K V+ + L + ++P+ ++ +
Sbjct: 1826 QDAYGDTALHDAIGKRAVKSLTSL-------------SITLALISPSETSVASMSSIMQP 1686
Query: 491 HSLLQAAREADLAKVKKTLA-LEIINFKQPQSHETALHCAVASLHPKRKQVTELLLRKGA 549
+ R A V + +++ F H T L L + + + LLR A
Sbjct: 1685 *RAMCLPRSASCTNVDRLWT*GKMMGFL----HFTWL------L*MDTRMLQQHLLRNRA 1536
Query: 550 NVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTALHRAAL 600
V+ +N TPL +A + H+ ++E+L A +N D G T LH A +
Sbjct: 1535 EVDIRNNRQQTPLLLAVSQGHSSLIELLVHAQADINVSDEDGDTCLHLALM 1383
Score = 53.5 bits (127), Expect = 5e-07, Method: Compositional matrix adjust.
Identities = 87/346 (25%), Positives = 132/346 (38%), Gaps = 41/346 (11%)
Frame = -3
Query: 218 SPLHFAAGFGRKDVVEHLLQMGANVHARDDGGLIPLHNACSFGHAEVVSLLLCQGADPNA 277
+ LH++A + DV++ LL GA ++A ++GG LH A + H + V +LL G D N
Sbjct: 2006 TALHYSAFGNQPDVLQLLLSKGAKINALNNGGCSTLHVAVNKQHIKCVHVLLNXGCDVNX 1827
Query: 278 RDNWNYTPLHEA----AIKGKIDVCIVLLQHGADPNIRNTDGKSALDLADPSAKAVLTGE 333
+D + T LH+A A+K + I L L PS +V
Sbjct: 1826 QDAYGDTALHDAIGKRAVKSLTSLSITLA------------------LISPSETSV---- 1713
Query: 334 YKKDELLEAARSGNEEKLMALLTPLNVNCHASD-----GRKSTPLHLA--AGYNRVRIVQ 386
A+ S + A+ P + +C D G+ LH + + Q
Sbjct: 1712 --------ASMSSIMQP*RAMCLPRSASCTNVDRLWT*GKMMGFLHFTWLL*MDTRMLQQ 1557
Query: 387 LLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASKN 446
LL++ A+V ++ PL A S GH + ELL+ A +N D T LH A +
Sbjct: 1556 HLLRNRAEVDIRNNRQQTPLLLAVSQGHSSLIELLVHAQADINVSDEDGDTCLHLALMRQ 1377
Query: 447 RV---------------------------EVCSLLLSHGADPTLVNCHGKSAVDMAP--- 476
V + L GA T N GK +D+
Sbjct: 1376 TVATEDSSRMLDSIRSQLGMGEDEAQTGAAIACYLAQQGASLTACNQQGKXPLDVTTDTR 1197
Query: 477 TPELRERLTYEFKGHSLLQAAREADLAKVKKTLALEIINFKQPQSH 522
T E+ ++ EF + E L +V A + F QP SH
Sbjct: 1196 TVEILQQFATEFCASNTKIEEEEGGLCEVCCNQA-ATVTF-QPCSH 1065
Score = 37.0 bits (84), Expect = 0.051, Method: Compositional matrix adjust.
Identities = 37/121 (30%), Positives = 50/121 (41%), Gaps = 3/121 (2%)
Frame = -3
Query: 836 RNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHV---DIAALLIKY 892
R TPL LA + + E L+ AD+N D+ G LH A V D + +L
Sbjct: 1514 RQQTPLLLAVSQGHSSLIELLVHAQADINVSDEDGDTCLHLALMRQTVATEDSSRMLDSI 1335
Query: 893 NTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTPLDLATADDIRALL 952
+ + AQ G C L GA T NQ+G+ PLD+ T D R +
Sbjct: 1334 --------RSQLGMGEDEAQTGAAIAC-YLAQQGASLTACNQQGKXPLDVTT--DTRTVE 1188
Query: 953 I 953
I
Sbjct: 1187 I 1185
Score = 35.4 bits (80), Expect = 0.16, Method: Compositional matrix adjust.
Identities = 21/73 (28%), Positives = 35/73 (47%)
Frame = -3
Query: 337 DELLEAARSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVH 396
D L + GN+ ++ LL +A + + LH+A ++ V +LL G DV+
Sbjct: 2009 DTALHYSAFGNQPDVLQLLLSKGAKINALNNGGCSTLHVAVNKQHIKCVHVLLNXGCDVN 1830
Query: 397 AKDKGGLVPLHNA 409
+D G LH+A
Sbjct: 1829 XQDAYGDTALHDA 1791
Score = 30.0 bits (66), Expect = 5.9, Method: Compositional matrix adjust.
Identities = 15/39 (38%), Positives = 21/39 (53%)
Frame = -3
Query: 839 TPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNA 877
+ LH+A +++ LL G DVN QD G LH+A
Sbjct: 1907 STLHVAVNKQHIKCVHVLLNXGCDVNXQDAYGDTALHDA 1791
>08473
Length = 942
Score = 63.5 bits (153), Expect = 5e-10, Method: Compositional matrix adjust.
Identities = 43/114 (37%), Positives = 56/114 (49%)
Frame = -1
Query: 674 NVNCRDLEGRHSTPLHFAAGYNRVSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVA 733
+V+ RD T LH A V LL GA+ + GG PL A G +
Sbjct: 942 DVDMRD--SNDMTALHHACAGLHYGCVHALLQGGANPTCMEMGGKTPLFYAAHRGEISIC 769
Query: 734 ELLVRHGASVNVADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPL 787
+LLV GA+VN AD TPL AA +G E + LLK GA+P +R+G+ L
Sbjct: 768 KLLVDKGANVNAADKMLITPLMVAAREGNREAVEFLLKRGANPNTADREGHLAL 607
Score = 61.2 bits (147), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 41/119 (34%), Positives = 58/119 (48%)
Frame = -1
Query: 827 NINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIA 886
+++ RD+ + T LH A + LL+ GA+ + GG PL AA G + I
Sbjct: 942 DVDMRDSN--DMTALHHACAGLHYGCVHALLQGGANPTCMEMGGKTPLFYAAHRGEISIC 769
Query: 887 ALLIKYNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTPLDLATA 945
LL+ VNA DK TPL AA++G + LL GA+P ++EG L A A
Sbjct: 768 KLLVDKGANVNAADKMLITPLMVAAREGNREAVEFLLKRGANPNTADREGHLALYYAMA 592
Score = 57.4 bits (137), Expect = 4e-08, Method: Compositional matrix adjust.
Identities = 44/120 (36%), Positives = 53/120 (44%), Gaps = 3/120 (2%)
Frame = -1
Query: 366 DGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHG 425
D T LH A V LLQ GA+ + GG PL A G + +LL+ G
Sbjct: 927 DSNDMTALHHACAGLHYGCVHALLQGGANPTCMEMGGKTPLFYAAHRGEISICKLLVDKG 748
Query: 426 ACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMAPT---PELRE 482
A VNA D TPL AA + E LL GA+P + G A+ A PELRE
Sbjct: 747 ANVNAADKMLITPLMVAAREGNREAVEFLLKRGANPNTADREGHLALYYAMAAGHPELRE 568
Score = 53.5 bits (127), Expect = 5e-07, Method: Compositional matrix adjust.
Identities = 38/100 (38%), Positives = 49/100 (49%)
Frame = -1
Query: 220 LHFAAGFGRKDVVEHLLQMGANVHARDDGGLIPLHNACSFGHAEVVSLLLCQGADPNARD 279
LH A V LLQ GAN + GG PL A G + LL+ +GA+ NA D
Sbjct: 906 LHHACAGLHYGCVHALLQGGANPTCMEMGGKTPLFYAAHRGEISICKLLVDKGANVNAAD 727
Query: 280 NWNYTPLHEAAIKGKIDVCIVLLQHGADPNIRNTDGKSAL 319
TPL AA +G + LL+ GA+PN + +G AL
Sbjct: 726 KMLITPLMVAAREGNREAVEFLLKRGANPNTADREGHLAL 607
Score = 53.1 bits (126), Expect = 8e-07, Method: Compositional matrix adjust.
Identities = 50/163 (30%), Positives = 74/163 (45%), Gaps = 3/163 (1%)
Frame = -1
Query: 241 NVHARDDGGLIPLHNACSFGHAEVVSLLLCQGADPNARDNWNYTPLHEAAIKGKIDVCIV 300
+V RD + LH+AC+ H V LL GA+P + TPL AA +G+I +C +
Sbjct: 942 DVDMRDSNDMTALHHACAGLHYGCVHALLQGGANPTCMEMGGKTPLFYAAHRGEISICKL 763
Query: 301 LLQHGADPNIRNTDGKSALDLADPSAKAVLTGEYKKDELLEAARSGNEEKLMALLT-PLN 359
L+ GA+ N + K ++T L+ AAR GN E + LL N
Sbjct: 762 LVDKGANVNAAD--------------KMLIT------PLMVAAREGNREAVEFLLKRGAN 643
Query: 360 VNCHASDGRKSTPLHLAAGYNRVRIV--QLLLQHGADVHAKDK 400
N +G + +AAG+ +R V LQ D+ + DK
Sbjct: 642 PNTADREGHLALYYAMAAGHPELREVFANAPLQASWDLRSPDK 514
Score = 52.4 bits (124), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 30/70 (42%), Positives = 39/70 (55%)
Frame = -1
Query: 534 HPKRKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDTLGQT 593
H + +LL+ KGANVN +K +TPL VAA + + +E L K GA N D G
Sbjct: 792 HRGEISICKLLVDKGANVNAADKMLITPLMVAAREGNREAVEFLLKRGANPNTADREGHL 613
Query: 594 ALHRAALAGH 603
AL+ A AGH
Sbjct: 612 ALYYAMAAGH 583
Score = 50.4 bits (119), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 44/147 (29%), Positives = 66/147 (44%)
Frame = -1
Query: 394 DVHAKDKGGLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSL 453
DV +D + LH+AC+ HY LL+ GA M++ TPL AA + + +C L
Sbjct: 942 DVDMRDSNDMTALHHACAGLHYGCVHALLQGGANPTCMEMGGKTPLFYAAHRGEISICKL 763
Query: 454 LLSHGADPTLVNCHGKSAVDMAPTPELRERLTYEFKGHSLLQAAREADLAKVKKTLALEI 513
L+ GA+ VN K M TP L+ AARE + V+ L
Sbjct: 762 LVDKGAN---VNAADK----MLITP--------------LMVAAREGNREAVEFLLKRGA 646
Query: 514 INFKQPQSHETALHCAVASLHPKRKQV 540
+ AL+ A+A+ HP+ ++V
Sbjct: 645 NPNTADREGHLALYYAMAAGHPELREV 565
Score = 48.1 bits (113), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 33/93 (35%), Positives = 47/93 (50%)
Frame = -1
Query: 201 LVDAANVNAKDMAGRKSSPLHFAAGFGRKDVVEHLLQMGANVHARDDGGLIPLHNACSFG 260
L AN +M G+ +PL +AA G + + L+ GANV+A D + PL A G
Sbjct: 858 LQGGANPTCMEMGGK--TPLFYAAHRGEISICKLLVDKGANVNAADKMLITPLMVAAREG 685
Query: 261 HAEVVSLLLCQGADPNARDNWNYTPLHEAAIKG 293
+ E V LL +GA+PN D + L+ A G
Sbjct: 684 NREAVEFLLKRGANPNTADREGHLALYYAMAAG 586
Score = 45.8 bits (107), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 39/129 (30%), Positives = 61/129 (47%), Gaps = 4/129 (3%)
Frame = -1
Query: 524 TALHCAVASLHPKRKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAK 583
TALH A A LH LL+ GAN TPL AA R + ++L GA
Sbjct: 912 TALHHACAGLH---YGCVHALLQGGANPTCMEMGGKTPLFYAAHRGEISICKLLVDKGAN 742
Query: 584 MNALDTLGQTALHRAALAGHLQTCRLLLSYGSDPSIISLQG----FTAAQMGNEAVQQIL 639
+NA D + T L AA G+ + LL G++P+ +G + A G+ ++++
Sbjct: 741 VNAADKMLITPLMVAAREGNREAVEFLLKRGANPNTADREGHLALYYAMAAGHPELREVF 562
Query: 640 SESTPIRTS 648
+ + P++ S
Sbjct: 561 A-NAPLQAS 538
Score = 45.1 bits (105), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 33/80 (41%), Positives = 44/80 (55%), Gaps = 1/80 (1%)
Frame = -1
Query: 186 LLEACRNGDVSRVKRLVD-AANVNAKDMAGRKSSPLHFAAGFGRKDVVEHLLQMGANVHA 244
L A G++S K LVD ANVNA D +PL AA G ++ VE LL+ GAN +
Sbjct: 807 LFYAAHRGEISICKLLVDKGANVNAADK--MLITPLMVAAREGNREAVEFLLKRGANPNT 634
Query: 245 RDDGGLIPLHNACSFGHAEV 264
D G + L+ A + GH E+
Sbjct: 633 ADREGHLALYYAMAAGHPEL 574
Score = 43.1 bits (100), Expect = 7e-04, Method: Compositional matrix adjust.
Identities = 29/92 (31%), Positives = 44/92 (47%)
Frame = -1
Query: 827 NINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIA 886
N C + G+ TPL AA + + + L++ GA+VNA DK + PL AA G+ +
Sbjct: 843 NPTCMEMGGK--TPLFYAAHRGEISICKLLVDKGANVNAADKMLITPLMVAAREGNREAV 670
Query: 887 ALLIKYNTCVNATDKWAFTPLHEAAQKGRTQL 918
L+K N D+ L+ A G +L
Sbjct: 669 EFLLKRGANPNTADREGHLALYYAMAAGHPEL 574
Score = 35.0 bits (79), Expect = 0.22, Method: Compositional matrix adjust.
Identities = 24/88 (27%), Positives = 40/88 (45%)
Frame = -1
Query: 862 DVNAQDKGGLIPLHNAASYGHVDIAALLIKYNTCVNATDKWAFTPLHEAAQKGRTQLCAL 921
DV+ +D + LH+A + H L++ + TPL AA +G +C L
Sbjct: 942 DVDMRDSNDMTALHHACAGLHYGCVHALLQGGANPTCMEMGGKTPLFYAAHRGEISICKL 763
Query: 922 LLAHGADPTMKNQEGQTPLDLATADDIR 949
L+ GA+ ++ TPL +A + R
Sbjct: 762 LVDKGANVNAADKMLITPLMVAAREGNR 679
>00540
Length = 3034
Score = 63.5 bits (153), Expect = 6e-10, Method: Compositional matrix adjust.
Identities = 41/104 (39%), Positives = 55/104 (52%)
Frame = -2
Query: 684 HSTPLHFAAGYNRVSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGASV 743
+STPL A + VV++L+ H A++ + G L AC GH +V E L+ GA V
Sbjct: 2970 NSTPLRAACYDGHLEVVQFLVEHKAEIEIANSHGHTCLMIACYRGHLDVVEYLLYLGAQV 2791
Query: 744 NVADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPL 787
N + T LH++A GK I KLLL GA K+ G TPL
Sbjct: 2790 NRRSVKGNTALHDSAESGKLSIMKLLLSKGAK-MAKDAYGQTPL 2662
Score = 62.4 bits (150), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 40/111 (36%), Positives = 57/111 (51%)
Frame = -2
Query: 833 TQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAALLIKY 892
T NSTPL A +LEV ++L+EH A++ + G L A GH+D+ L+
Sbjct: 2982 TTRSNSTPLRAACYDGHLEVVQFLVEHKAEIEIANSHGHTCLMIACYRGHLDVVEYLLYL 2803
Query: 893 NTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTPLDLA 943
VN T LH++A+ G+ + LLL+ GA K+ GQTPL A
Sbjct: 2802 GAQVNRRSVKGNTALHDSAESGKLSIMKLLLSKGAK-MAKDAYGQTPLSAA 2653
Score = 56.6 bits (135), Expect = 6e-08, Method: Compositional matrix adjust.
Identities = 34/90 (37%), Positives = 48/90 (53%)
Frame = -2
Query: 370 STPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGACVN 429
STPL A + +VQ L++H A++ + G L AC GH +V E LL GA VN
Sbjct: 2967 STPLRAACYDGHLEVVQFLVEHKAEIEIANSHGHTCLMIACYRGHLDVVEYLLYLGAQVN 2788
Query: 430 AMDLWQFTPLHEAASKNRVEVCSLLLSHGA 459
+ T LH++A ++ + LLLS GA
Sbjct: 2787 RRSVKGNTALHDSAESGKLSIMKLLLSKGA 2698
Score = 49.7 bits (117), Expect = 8e-06, Method: Compositional matrix adjust.
Identities = 51/188 (27%), Positives = 69/188 (36%)
Frame = -2
Query: 425 GACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMAPTPELRERL 484
GA VN TPL A +EV L+ H A+ + N HG + + +A
Sbjct: 3000 GAEVNQTTRSNSTPLRAACYDGHLEVVQFLVEHKAEIEIANSHGHTCLMIAC-------- 2845
Query: 485 TYEFKGHSLLQAAREADLAKVKKTLALEIINFKQPQSHETALHCAVASLHPKRKQVTELL 544
++GH V E L
Sbjct: 2844 ---YRGH----------------------------------------------LDVVEYL 2812
Query: 545 LRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTALHRAALAGHL 604
L GA VN ++ T LH +AE +M++L GAKM A D GQT L AA+ GH
Sbjct: 2811 LYLGAQVNRRSVKGNTALHDSAESGKLSIMKLLLSKGAKM-AKDAYGQTPLSAAAMTGHE 2635
Query: 605 QTCRLLLS 612
+ R L+S
Sbjct: 2634 EIVRYLIS 2611
Score = 49.7 bits (117), Expect = 9e-06, Method: Compositional matrix adjust.
Identities = 33/90 (36%), Positives = 46/90 (51%)
Frame = -2
Query: 217 SSPLHFAAGFGRKDVVEHLLQMGANVHARDDGGLIPLHNACSFGHAEVVSLLLCQGADPN 276
S+PL A G +VV+ L++ A + + G L AC GH +VV LL GA N
Sbjct: 2967 STPLRAACYDGHLEVVQFLVEHKAEIEIANSHGHTCLMIACYRGHLDVVEYLLYLGAQVN 2788
Query: 277 ARDNWNYTPLHEAAIKGKIDVCIVLLQHGA 306
R T LH++A GK+ + +LL GA
Sbjct: 2787 RRSVKGNTALHDSAESGKLSIMKLLLSKGA 2698
Score = 48.9 bits (115), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 44/158 (27%), Positives = 68/158 (43%)
Frame = -2
Query: 547 KGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTALHRAALAGHLQT 606
KGA VN+ + TPL A H +V++ L +H A++ ++ G T L A GHL
Sbjct: 3003 KGAEVNQTTRSNSTPLRAACYDGHLEVVQFLVEHKAEIEIANSHGHTCLMIACYRGHLDV 2824
Query: 607 CRLLLSYGSDPSIISLQGFTAAQMGNEAVQQILSESTPIRTSDVDYRLLEASKAGDLETV 666
LL G+ + S++G TA L +++++G L +
Sbjct: 2823 VEYLLYLGAQVNRRSVKGNTA--------------------------LHDSAESGKLSIM 2722
Query: 667 KQLCSSQNVNCRDLEGRHSTPLHFAAGYNRVSVVEYLL 704
K L S +D G+ TPL AA +V YL+
Sbjct: 2721 KLLLSKGAKMAKDAYGQ--TPLSAAAMTGHEEIVRYLI 2614
Score = 46.6 bits (109), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 29/77 (37%), Positives = 41/77 (53%)
Frame = -2
Query: 539 QVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTALHRA 598
+V + L+ A + N T L +A R H DV+E L GA++N G TALH +
Sbjct: 2928 EVVQFLVEHKAEIEIANSHGHTCLMIACYRGHLDVVEYLLYLGAQVNRRSVKGNTALHDS 2749
Query: 599 ALAGHLQTCRLLLSYGS 615
A +G L +LLLS G+
Sbjct: 2748 AESGKLSIMKLLLSKGA 2698
Score = 45.1 bits (105), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 39/130 (30%), Positives = 59/130 (45%), Gaps = 12/130 (9%)
Frame = -2
Query: 239 GANVHARDDGGLIPLHNACSFGHAEVVSLLLCQGADPNARDNWNYTPLHEAAIKGKIDVC 298
GA V+ PL AC GH EVV L+ A+ ++ +T L A +G +DV
Sbjct: 3000 GAEVNQTTRSNSTPLRAACYDGHLEVVQFLVEHKAEIEIANSHGHTCLMIACYRGHLDVV 2821
Query: 299 IVLLQHGADPNIRNTDGKSAL-DLADPSAKAVL-----------TGEYKKDELLEAARSG 346
LL GA N R+ G +AL D A+ +++ Y + L AA +G
Sbjct: 2820 EYLLYLGAQVNRRSVKGNTALHDSAESGKLSIMKLLLSKGAKMAKDAYGQTPLSAAAMTG 2641
Query: 347 NEEKLMALLT 356
+EE + L++
Sbjct: 2640 HEEIVRYLIS 2611
Score = 38.1 bits (87), Expect = 0.021, Method: Compositional matrix adjust.
Identities = 30/90 (33%), Positives = 42/90 (46%), Gaps = 15/90 (16%)
Frame = -2
Query: 246 DDGGLIPLHNAC-----SFGHAE--------VVSLLLCQGADPNARDNWNYTPLHEAAIK 292
D G PLH AC SFG V +L+ GAD NARD+ LH A++
Sbjct: 1854 DPDGASPLHLACMENISSFGRVRMSHFPSLSVTRILIKVGADTNARDSQGNVALHFASMG 1675
Query: 293 GKIDVCIV--LLQHGADPNIRNTDGKSALD 320
K+ + +V LL GA ++ N + + D
Sbjct: 1674 KKVRMAVVEALLAGGAHADVCNKNHLTLFD 1585
Score = 37.7 bits (86), Expect = 0.034, Method: Compositional matrix adjust.
Identities = 28/86 (32%), Positives = 42/86 (48%)
Frame = -2
Query: 371 TPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGACVNA 430
T L +A + +V+ LL GA V+ + G LH++ G + +LLL GA + A
Sbjct: 2865 TCLMIACYRGHLDVVEYLLYLGAQVNRRSVKGNTALHDSAESGKLSIMKLLLSKGAKM-A 2689
Query: 431 MDLWQFTPLHEAASKNRVEVCSLLLS 456
D + TPL AA E+ L+S
Sbjct: 2688 KDAYGQTPLSAAAMTGHEEIVRYLIS 2611
>02055
Length = 1740
Score = 63.2 bits (152), Expect = 8e-10, Method: Compositional matrix adjust.
Identities = 74/256 (28%), Positives = 111/256 (43%), Gaps = 10/256 (3%)
Frame = +3
Query: 544 LLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNA-LDTLGQTALHRAALAG 602
L+R GA+V+ N TPLH+A A+++ M L ++GA +NA L T LH A
Sbjct: 381 LIRCGADVDFCNMFGDTPLHIATVHANHEAMGALVRNGANVNARAKFLNSTPLHVACRLR 560
Query: 603 HLQTCRLLLSYGSDPSIISLQGFTAAQM----GNEAVQQILSESTP--IRTSDVDYRLLE 656
Q LL+ G+ + G T QM + AV IL S P +RT D +
Sbjct: 561 GQQEVALLIQLGARIDVNDATGTTPLQMACKRADPAVVNILLRSQPSIVRTEDANKLFKY 740
Query: 657 ASKAGDLETVKQLCSS-QNVNCRDLEGRHSTPLHFAAGYNRVSVVEYLLHHGA-DVHAKD 714
A + L VK LC + VN EG +TP+H A + ++ + + +D
Sbjct: 741 AIQKRQLHIVKMLCEAGVAVN---YEG--TTPVHIAMDNQAWDIAKFFITSNKHNFDGRD 905
Query: 715 KGGLVPLHNACSYG-HYEVAELLVRHGASVNVADLWKFTPLHEAAAKGKYEICKLLLKHG 773
G PL A G + + L+ G S++ D T L A + + + +L+
Sbjct: 906 SKGRTPLCLALLSGADFHMVSFLLNVGYSIDQVDSNGETWLLRAGRQNEENLVCSILRFN 1085
Query: 774 ADPTKKNRDGNTPLDL 789
+ NR N PL L
Sbjct: 1086PNVYAPNR-YNVPLVL 1130
Score = 53.1 bits (126), Expect = 7e-07, Method: Compositional matrix adjust.
Identities = 65/241 (26%), Positives = 110/241 (45%), Gaps = 18/241 (7%)
Frame = +3
Query: 232 VEHLLQMGANVHARDDGGLIPLHNACSFGHAEVVSLLLCQGADPNARDNW-NYTPLHEAA 290
V+ L++ GA+V + G PLH A + E + L+ GA+ NAR + N TPLH A
Sbjct: 372 VDDLIRCGADVDFCNMFGDTPLHIATVHANHEAMGALVRNGANVNARAKFLNSTPLHVAC 551
Query: 291 -IKGKIDVCIVLLQHGADPNIRNTDGKSALDL----ADPSAKAVL-------TGEYKKDE 338
++G+ +V + L+Q GA ++ + G + L + ADP+ +L ++
Sbjct: 552 RLRGQQEVAL-LIQLGARIDVNDATGTTPLQMACKRADPAVVNILLRSQPSIVRTEDANK 728
Query: 339 LLEAARSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLL---QHGADV 395
L + A + ++ +L V A + +TP+H+A I + + +H D
Sbjct: 729 LFKYAIQKRQLHIVKMLCEAGV---AVNYEGTTPVHIAMDNQAWDIAKFFITSNKHNFD- 896
Query: 396 HAKDKGGLVPLHNACSYG-HYEVTELLLKHGACVNAMDLWQFTPLHEAASKNRVE-VCSL 453
+D G PL A G + + LL G ++ +D T L A +N VCS+
Sbjct: 897 -GRDSKGRTPLCLALLSGADFHMVSFLLNVGYSIDQVDSNGETWLLRAGRQNEENLVCSI 1073
Query: 454 L 454
L
Sbjct: 1074L 1076
Score = 52.0 bits (123), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 71/235 (30%), Positives = 94/235 (40%), Gaps = 3/235 (1%)
Frame = +3
Query: 700 VEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGASVNV-ADLWKFTPLHEAA 758
V+ L+ GADV + G PLH A + ++E LVR+GA+VN A TPLH A
Sbjct: 372 VDDLIRCGADVDFCNMFGDTPLHIATVHANHEAMGALVRNGANVNARAKFLNSTPLHVAC 551
Query: 759 -AKGKYEICKLLLKHGADPTKKNRDGNTPLDLV-KEGDTDIQXXXXXXXXXXXXXXXXXX 816
+G+ E+ LL++ GA + G TPL + K D +
Sbjct: 552 RLRGQQEVA-LLIQLGARIDVNDATGTTPLQMACKRADPAV---------------VNIL 683
Query: 817 XRVQKLCTPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHN 876
R Q P + D + A L + + L E G VN + G P+H
Sbjct: 684 LRSQ----PSIVRTEDA----NKLFKYAIQKRQLHIVKMLCEAGVAVNYE---GTTPVHI 830
Query: 877 AASYGHVDIAALLIKYNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTM 931
A DIA I N K F KGRT LC LL+ GAD M
Sbjct: 831 AMDNQAWDIAKFFITSN-------KHNFDG---RDSKGRTPLCLALLS-GADFHM 962
Score = 52.0 bits (123), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 59/246 (23%), Positives = 95/246 (38%), Gaps = 5/246 (2%)
Frame = +3
Query: 674 NVNCRDLEGRHSTPLHFAAGYNRVSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVA 733
NVN R + +STPLH A V L+ GA + D G PL AC V
Sbjct: 498 NVNAR-AKFLNSTPLHVACRLRGQQEVALLIQLGARIDVNDATGTTPLQMACKRADPAVV 674
Query: 734 ELLVRHGASV----NVADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPLDL 789
+L+R S+ + L+K+ A K + I K+L + G N +G TP+ +
Sbjct: 675 NILLRSQPSIVRTEDANKLFKY-----AIQKRQLHIVKMLCEAG---VAVNYEGTTPVHI 830
Query: 790 VKEGDT-DIQXXXXXXXXXXXXXXXXXXXRVQKLCTPENINCRDTQGRNSTPLHLAAGYN 848
+ DI N + RD++GR L L +G
Sbjct: 831 AMDNQAWDIAKFFITS-------------------NKHNFDGRDSKGRTPLCLALLSGA- 950
Query: 849 NLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAALLIKYNTCVNATDKWAFTPLH 908
+ + +LL G ++ D G L A ++ ++++N V A +++ +
Sbjct: 951 DFHMVSFLLNVGYSIDQVDSNGETWLLRAGRQNEENLVCSILRFNPNVYAPNRYNVPLVL 1130
Query: 909 EAAQKG 914
E KG
Sbjct: 1131ELFDKG 1148
Score = 46.2 bits (108), Expect = 9e-05, Method: Compositional matrix adjust.
Identities = 59/233 (25%), Positives = 96/233 (41%), Gaps = 12/233 (5%)
Frame = +3
Query: 203 DAANVNAKDMAGRKSSPLHFAAGFGRKDVVEHLLQMGANVHARDDGGLIPLHNACSFGHA 262
+ ANVNA+ S+PLH A + V L+Q+GA + D G PL AC
Sbjct: 489 NGANVNAR-AKFLNSTPLHVACRLRGQQEVALLIQLGARIDVNDATGTTPLQMACKRADP 665
Query: 263 EVVSLLLCQGADPNARDNWNYTPLHEAAI-KGKIDVCIVLLQHGADPNIRNTD------G 315
VV++LL + P+ + L + AI K ++ + +L + G N T
Sbjct: 666 AVVNILL--RSQPSIVRTEDANKLFKYAIQKRQLHIVKMLCEAGVAVNYEGTTPVHIAMD 839
Query: 316 KSALDLAD---PSAKAVLTGEYKKDE--LLEAARSGNEEKLMALLTPLNVNCHASDGRKS 370
A D+A S K G K L A SG + +++ L + + D
Sbjct: 840 NQAWDIAKFFITSNKHNFDGRDSKGRTPLCLALLSGADFHMVSFLLNVGYSIDQVDSNGE 1019
Query: 371 TPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLK 423
T L A N +V +L+ +V+A ++ + + GHY + L++
Sbjct: 1020TWLLRAGRQNEENLVCSILRFNPNVYAPNRYNVPLVLELFDKGHYAIVNHLVR 1178
Score = 44.3 bits (103), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 62/243 (25%), Positives = 101/243 (41%), Gaps = 9/243 (3%)
Frame = +3
Query: 383 RIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGACVNA-MDLWQFTPLHE 441
R V L++ GADV + G PLH A + ++E L+++GA VNA TPLH
Sbjct: 366 REVDDLIRCGADVDFCNMFGDTPLHIATVHANHEAMGALVRNGANVNARAKFLNSTPLHV 545
Query: 442 AASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMAPTPELRERLTYEFKGHSLLQAAREAD 501
A + +LL+ GA + + G + + M A + AD
Sbjct: 546 ACRLRGQQEVALLIQLGARIDVNDATGTTPLQM---------------------ACKRAD 662
Query: 502 LAKVKKTLALEIINFKQPQ--SHETALHCAVASLHPKRKQVTELLLRKGANVNEKNKDFM 559
A V I+ QP E A ++ ++ + ++L G VN +
Sbjct: 663 PAVVN------ILLRSQPSIVRTEDANKLFKYAIQKRQLHIVKMLCEAGVAVNYEGT--- 815
Query: 560 TPLHVAAERAHNDVMEVL---HKHGAKMNALDTLGQTALHRAALAG---HLQTCRLLLSY 613
TP+H+A + D+ + +KH + D+ G+T L A L+G H+ + L + Y
Sbjct: 816 TPVHIAMDNQAWDIAKFFITSNKHN--FDGRDSKGRTPLCLALLSGADFHMVSFLLNVGY 989
Query: 614 GSD 616
D
Sbjct: 990 SID 998
Score = 42.4 bits (98), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 31/89 (34%), Positives = 45/89 (50%), Gaps = 1/89 (1%)
Frame = +3
Query: 856 LLEHGADVNAQDKGGLIPLHNAASYGHVDIAALLIKYNTCVNATDKWA-FTPLHEAAQKG 914
L+ GADV+ + G PLH A + + + L++ VNA K+ TPLH A +
Sbjct: 381 LIRCGADVDFCNMFGDTPLHIATVHANHEAMGALVRNGANVNARAKFLNSTPLHVACRLR 560
Query: 915 RTQLCALLLAHGADPTMKNQEGQTPLDLA 943
Q ALL+ GA + + G TPL +A
Sbjct: 561 GQQEVALLIQLGARIDVNDATGTTPLQMA 647
Score = 40.4 bits (93), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 40/135 (29%), Positives = 59/135 (43%), Gaps = 5/135 (3%)
Frame = +3
Query: 346 GNEEKLMALL-TPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLV 404
N E + AL+ NVN A STPLH+A + V LL+Q GA + D G
Sbjct: 456 ANHEAMGALVRNGANVNARAK-FLNSTPLHVACRLRGQQEVALLIQLGARIDVNDATGTT 632
Query: 405 PLHNACSYGHYEVTELLLKHGACV----NAMDLWQFTPLHEAASKNRVEVCSLLLSHGAD 460
PL AC V +LL+ + +A L+++ A K ++ + +L G
Sbjct: 633 PLQMACKRADPAVVNILLRSQPSIVRTEDANKLFKY-----AIQKRQLHIVKMLCEAG-- 791
Query: 461 PTLVNCHGKSAVDMA 475
VN G + V +A
Sbjct: 792 -VAVNYEGTTPVHIA 833
Score = 32.7 bits (73), Expect = 1.1, Method: Compositional matrix adjust.
Identities = 54/223 (24%), Positives = 84/223 (37%), Gaps = 21/223 (9%)
Frame = +3
Query: 263 EVVSLLLCQGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGADPNIRNTDGKSALDLA 322
EV L+ C GAD + + + TPLH A + + L+++GA+ N R
Sbjct: 369 EVDDLIRC-GADVDFCNMFGDTPLHIATVHANHEAMGALVRNGANVNAR----------- 512
Query: 323 DPSAKAVLTGEYKKDELLEAARSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRV 382
++ L A ++ +ALL L +D +TPL +A
Sbjct: 513 ---------AKFLNSTPLHVACRLRGQQEVALLIQLGARIDVNDATGTTPLQMACKRADP 665
Query: 383 RIVQLLLQ-HGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGACVN---------AMD 432
+V +LL+ + V +D L A + ++L + G VN AMD
Sbjct: 666 AVVNILLRSQPSIVRTEDANKLFKY--AIQKRQLHIVKMLCEAGVAVNYEGTTPVHIAMD 839
Query: 433 --LWQFTPLHEAA---------SKNRVEVCSLLLSHGADPTLV 464
W + SK R +C LLS GAD +V
Sbjct: 840 NQAWDIAKFFITSNKHNFDGRDSKGRTPLCLALLS-GADFHMV 965
>03590
Length = 1068
Score = 48.5 bits (114), Expect(2) = 1e-09, Method: Compositional matrix adjust.
Identities = 39/122 (31%), Positives = 52/122 (42%), Gaps = 11/122 (9%)
Frame = +3
Query: 661 GDLETVKQLCSSQNVNCRDLEGRHSTPLHFAAGYNR------VSVVEYLLHHGADVHAKD 714
G +T Q + C T LH A NR ++ E+LL H ADV AK+
Sbjct: 696 GRRDTAAQAAGGERPECEQQGQARDTVLHTAVSNNRGDANDSTALEEFLLEHKADVFAKN 875
Query: 715 KGGLVPLHN---ACSYGHYEVAELLV--RHGASVNVADLWKFTPLHEAAAKGKYEICKLL 769
G +P+H C E+ LL V+ L F+PLH AAA+G C L
Sbjct: 876 DDGYMPIHCVFVGCGPDPIELLSLLTAAMKDQQVDEPVLSGFSPLHFAAARGATICCMHL 1055
Query: 770 LK 771
L+
Sbjct: 1056LQ 1061
Score = 33.9 bits (76), Expect(2) = 1e-09, Method: Compositional matrix adjust.
Identities = 25/84 (29%), Positives = 42/84 (50%), Gaps = 5/84 (5%)
Frame = +1
Query: 543 LLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTALH-----R 597
L+LR ++ + + TPL +AA D +++L + GA ++AL H
Sbjct: 391 LILRYKPDLECQTLNSDTPLVLAARSQSADKVKLLAEMGANVDALIKSKLNGNHVTPCLW 570
Query: 598 AALAGHLQTCRLLLSYGSDPSIIS 621
A+ +L +LLL YG+DP +S
Sbjct: 571 MAMQKNLPLVKLLLKYGADPKAVS 642
Score = 39.7 bits (91), Expect = 0.009, Method: Compositional matrix adjust.
Identities = 33/105 (31%), Positives = 45/105 (42%), Gaps = 11/105 (10%)
Frame = +3
Query: 362 CHASDGRKSTPLHLAAGYNR------VRIVQLLLQHGADVHAKDKGGLVPLHN---ACSY 412
C + T LH A NR + + LL+H ADV AK+ G +P+H C
Sbjct: 744 CEQQGQARDTVLHTAVSNNRGDANDSTALEEFLLEHKADVFAKNDDGYMPIHCVFVGCGP 923
Query: 413 GHYEVTELLLK--HGACVNAMDLWQFTPLHEAASKNRVEVCSLLL 455
E+ LL V+ L F+PLH AA++ C LL
Sbjct: 924 DPIELLSLLTAAMKDQQVDEPVLSGFSPLHFAAARGATICCMHLL 1058
Score = 39.3 bits (90), Expect = 0.011, Method: Compositional matrix adjust.
Identities = 33/109 (30%), Positives = 48/109 (44%), Gaps = 11/109 (10%)
Frame = +3
Query: 826 ENINCRDTQGRNSTPLHLAAGYN------NLEVAEYLLEHGADVNAQDKGGLIPLHN--- 876
E C T LH A N + + E+LLEH ADV A++ G +P+H
Sbjct: 732 ERPECEQQGQARDTVLHTAVSNNRGDANDSTALEEFLLEHKADVFAKNDDGYMPIHCVFV 911
Query: 877 AASYGHVDIAALLIK--YNTCVNATDKWAFTPLHEAAQKGRTQLCALLL 923
+++ +LL + V+ F+PLH AA +G T C LL
Sbjct: 912 GCGPDPIELLSLLTAAMKDQQVDEPVLSGFSPLHFAAARGATICCMHLL 1058
Score = 38.9 bits (89), Expect = 0.012, Method: Compositional matrix adjust.
Identities = 31/99 (31%), Positives = 47/99 (47%), Gaps = 11/99 (11%)
Frame = +3
Query: 216 KSSPLHFAAGFGRKD------VVEHLLQMGANVHARDDGGLIPLHN---ACSFGHAEVVS 266
+ + LH A R D + E LL+ A+V A++D G +P+H C E++S
Sbjct: 765 RDTVLHTAVSNNRGDANDSTALEEFLLEHKADVFAKNDDGYMPIHCVFVGCGPDPIELLS 944
Query: 267 LLLCQGADPNARDNW--NYTPLHEAAIKGKIDVCIVLLQ 303
LL D + ++PLH AA +G C+ LLQ
Sbjct: 945 LLTAAMKDQQVDEPVLSGFSPLHFAAARGATICCMHLLQ 1061
Score = 32.3 bits (72), Expect = 1.2, Method: Compositional matrix adjust.
Identities = 32/109 (29%), Positives = 45/109 (41%), Gaps = 11/109 (10%)
Frame = +1
Query: 218 SPLHFAAGFGRKDVVEHLLQMGANVHARDDGGLIPLHNACSFGHA-----EVVSLLLCQG 272
+PL AA D V+ L +MGANV A L H A +V LLL G
Sbjct: 442 TPLVLAARSQSADKVKLLAEMGANVDALIKSKLNGNHVTPCLWMAMQKNLPLVKLLLKYG 621
Query: 273 ADPNARDNWNYTPLHEAAIKGK------IDVCIVLLQHGADPNIRNTDG 315
ADP A + L ++ + I + +L++ G N R+ G
Sbjct: 622 ADPKAVSAYTKETLMHCLVRDRSAEGDVIQLLKLLVEKGLSVNSRDKRG 768
Score = 30.0 bits (66), Expect = 6.3, Method: Compositional matrix adjust.
Identities = 34/112 (30%), Positives = 54/112 (48%), Gaps = 10/112 (8%)
Frame = +1
Query: 646 RTSDVDYRLLEASKAGDLETVKQLCS-SQNVNC---RDLEGRHSTPLHFAAGYNRVSVVE 701
+T + D L+ A+++ + VK L NV+ L G H TP + A + +V+
Sbjct: 424 QTLNSDTPLVLAARSQSADKVKLLAEMGANVDALIKSKLNGNHVTPCLWMAMQKNLPLVK 603
Query: 702 YLLHHGAD---VHAKDKGGLV--PLHNACSYGHY-EVAELLVRHGASVNVAD 747
LL +GAD V A K L+ + + + G ++ +LLV G SVN D
Sbjct: 604 LLLKYGADPKAVSAYTKETLMHCLVRDRSAEGDVIQLLKLLVEKGLSVNSRD 759
Score = 29.6 bits (65), Expect = 7.9, Method: Compositional matrix adjust.
Identities = 24/91 (26%), Positives = 42/91 (46%), Gaps = 5/91 (5%)
Frame = +1
Query: 387 LLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQF-----TPLHE 441
L+L++ D+ + PL A + +LL + GA V+A+ + TP
Sbjct: 391 LILRYKPDLECQTLNSDTPLVLAARSQSADKVKLLAEMGANVDALIKSKLNGNHVTPCLW 570
Query: 442 AASKNRVEVCSLLLSHGADPTLVNCHGKSAV 472
A + + + LLL +GADP V+ + K +
Sbjct: 571 MAMQKNLPLVKLLLKYGADPKAVSAYTKETL 663
>28113
Length = 449
Score = 62.4 bits (150), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 43/108 (39%), Positives = 58/108 (53%), Gaps = 1/108 (0%)
Frame = -3
Query: 215 RKSSPLHFAAGFGRKDVVEHLLQMGANVHARDDGGLIPLHNACSFGHAEVVSLLLCQGAD 274
R PLH +A G V+ LL G + +D +H A +G A+VV +LL G
Sbjct: 336 RDKYPLHASAAQGDVHHVQSLLNHGHHHSKKDSIAWAAIHYASWYGSADVVEILLDAGCS 157
Query: 275 PNARDNWNYTPLHEAAIKGKIDVCIVLLQHGA-DPNIRNTDGKSALDL 321
PN ++ TPLH AA KG DV L+Q A D N+R+ DGK A+D+
Sbjct: 156 PNLTNSELLTPLHIAAKKGFPDVAEHLVQAEAIDLNLRDKDGKRAIDI 13
Score = 55.8 bits (133), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 33/118 (27%), Positives = 60/118 (50%), Gaps = 1/118 (0%)
Frame = -3
Query: 829 NCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAAL 888
N + + R+ PLH +A ++ + LL HG + +D +H A+ YG D+ +
Sbjct: 357 NPVEPRWRDKYPLHASAAQGDVHHVQSLLNHGHHHSKKDSIAWAAIHYASWYGSADVVEI 178
Query: 889 LIKYNTCVNATDKWAFTPLHEAAQKGRTQLCA-LLLAHGADPTMKNQEGQTPLDLATA 945
L+ N T+ TPLH AA+KG + L+ A D +++++G+ +D+ T+
Sbjct: 177 LLDAGCSPNLTNSELLTPLHIAAKKGFPDVAEHLVQAEAIDLNLRDKDGKRAIDICTS 4
Score = 53.9 bits (128), Expect = 5e-07, Method: Compositional matrix adjust.
Identities = 37/108 (34%), Positives = 56/108 (51%), Gaps = 1/108 (0%)
Frame = -3
Query: 683 RHSTPLHFAAGYNRVSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGAS 742
R PLH +A V V+ LL+HG KD +H A YG +V E+L+ G S
Sbjct: 336 RDKYPLHASAAQGDVHHVQSLLNHGHHHSKKDSIAWAAIHYASWYGSADVVEILLDAGCS 157
Query: 743 VNVADLWKFTPLHEAAAKGKYEICKLLLKHGA-DPTKKNRDGNTPLDL 789
N+ + TPLH AA KG ++ + L++ A D +++DG +D+
Sbjct: 156 PNLTNSELLTPLHIAAKKGFPDVAEHLVQAEAIDLNLRDKDGKRAIDI 13
Score = 53.5 bits (127), Expect = 5e-07, Method: Compositional matrix adjust.
Identities = 39/108 (36%), Positives = 50/108 (46%), Gaps = 1/108 (0%)
Frame = -3
Query: 368 RKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGAC 427
R PLH +A V VQ LL HG KD +H A YG +V E+LL G
Sbjct: 336 RDKYPLHASAAQGDVHHVQSLLNHGHHHSKKDSIAWAAIHYASWYGSADVVEILLDAGCS 157
Query: 428 VNAMDLWQFTPLHEAASKNRVEVCS-LLLSHGADPTLVNCHGKSAVDM 474
N + TPLH AA K +V L+ + D L + GK A+D+
Sbjct: 156 PNLTNSELLTPLHIAAKKGFPDVAEHLVQAEAIDLNLRDKDGKRAIDI 13
Score = 37.4 bits (85), Expect = 0.036, Method: Compositional matrix adjust.
Identities = 20/57 (35%), Positives = 32/57 (56%), Gaps = 1/57 (1%)
Frame = -3
Query: 540 VTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVME-VLHKHGAKMNALDTLGQTAL 595
V E+LL G + N N + +TPLH+AA++ DV E ++ +N D G+ A+
Sbjct: 189 VVEILLDAGCSPNLTNSELLTPLHIAAKKGFPDVAEHLVQAEAIDLNLRDKDGKRAI 19
Score = 33.5 bits (75), Expect = 0.59, Method: Compositional matrix adjust.
Identities = 28/109 (25%), Positives = 51/109 (46%), Gaps = 4/109 (3%)
Frame = -3
Query: 561 PLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTALHRAALAGHLQTCRLLLSYGSDPSII 620
PLH +A + ++ L HG + D++ A+H A+ G +LL G P++
Sbjct: 324 PLHASAAQGDVHHVQSLLNHGHHHSKKDSIAWAAIHYASWYGSADVVEILLDAGCSPNLT 145
Query: 621 SLQGFT----AAQMGNEAVQQILSESTPIRTSDVDYRLLEASKAGDLET 665
+ + T AA+ G V + L ++ I D++ R + +A D+ T
Sbjct: 144 NSELLTPLHIAAKKGFPDVAEHLVQAEAI---DLNLRDKDGKRAIDICT 7
>09180
Length = 610
Score = 59.7 bits (143), Expect = 7e-09, Method: Compositional matrix adjust.
Identities = 44/138 (31%), Positives = 67/138 (48%)
Frame = +3
Query: 249 GLIPLHNACSFGHAEVVSLLLCQGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGADP 308
G LH + + G+ V+++LL G D NA+D +T LH A G+ D C VL+ H D
Sbjct: 165 GATALHVSAAKGYINVMNVLLQAGVDINAQDADGWTSLHAAVHWGQEDSCQVLVDHFCDM 344
Query: 309 NIRNTDGKSALDLADPSAKAVLTGEYKKDELLEAARSGNEEKLMALLTPLNVNCHASDGR 368
+++N G + DLAD VL KK L A N + + TP H S R
Sbjct: 345 DVKNNAGHTVFDLADKEMLKVLEELKKKQAKLRTASESNSD---IIHTP----GHGS-KR 500
Query: 369 KSTPLHLAAGYNRVRIVQ 386
+S+ +++G + I +
Sbjct: 501 RSSVTRMSSGQKQSLITK 554
Score = 48.1 bits (113), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 26/82 (31%), Positives = 46/82 (56%)
Frame = +3
Query: 560 TPLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTALHRAALAGHLQTCRLLLSYGSDPSI 619
T LHV+A + + +VM VL + G +NA D G T+LH A G +C++L+ + D +
Sbjct: 171 TALHVSAAKGYINVMNVLLQAGVDINAQDADGWTSLHAAVHWGQEDSCQVLVDHFCDMDV 350
Query: 620 ISLQGFTAAQMGNEAVQQILSE 641
+ G T + ++ + ++L E
Sbjct: 351 KNNAGHTVFDLADKEMLKVLEE 416
Score = 47.8 bits (112), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 26/88 (29%), Positives = 46/88 (52%), Gaps = 4/88 (4%)
Frame = +3
Query: 341 EAARSGNEEKLMA----LLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVH 396
+AAR E+ +M L N+ +A +T LH++A + ++ +LLQ G D++
Sbjct: 69 DAARKEEEDMMMEDANRWLQNKNIEDNAHPKTGATALHVSAAKGYINVMNVLLQAGVDIN 248
Query: 397 AKDKGGLVPLHNACSYGHYEVTELLLKH 424
A+D G LH A +G + ++L+ H
Sbjct: 249 AQDADGWTSLHAAVHWGQEDSCQVLVDH 332
Score = 44.7 bits (104), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 31/114 (27%), Positives = 44/114 (38%)
Frame = +3
Query: 838 STPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAALLIKYNTCVN 897
+T LH++A + V LL+ G D+NAQD G LH A +G D
Sbjct: 168 ATALHVSAAKGYINVMNVLLQAGVDINAQDADGWTSLHAAVHWGQEDS------------ 311
Query: 898 ATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTPLDLATADDIRAL 951
C +L+ H D +KN G T DLA + ++ L
Sbjct: 312 ---------------------CQVLVDHFCDMDVKNNAGHTVFDLADKEMLKVL 410
>28494
Length = 463
Score = 59.3 bits (142), Expect = 9e-09, Method: Compositional matrix adjust.
Identities = 31/76 (40%), Positives = 45/76 (59%)
Frame = -1
Query: 700 VEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAAA 759
V+ LL GAD++ + GL LH AC + ++ E LV A V+V D +TPLH A+
Sbjct: 271 VKKLLERGADINTANVDGLTALHQACIDDNLDMVEFLVEQNADVDVCDNEGWTPLHATAS 92
Query: 760 KGKYEICKLLLKHGAD 775
G EI + LL++GA+
Sbjct: 91 CGFTEIARYLLENGAN 44
Score = 57.0 bits (136), Expect = 5e-08, Method: Compositional matrix adjust.
Identities = 32/89 (35%), Positives = 50/89 (56%)
Frame = -1
Query: 223 AAGFGRKDVVEHLLQMGANVHARDDGGLIPLHNACSFGHAEVVSLLLCQGADPNARDNWN 282
A G +D V+ LL+ GA+++ + GL LH AC + ++V L+ Q AD + DN
Sbjct: 298 ACSSGDRDEVKKLLERGADINTANVDGLTALHQACIDDNLDMVEFLVEQNADVDVCDNEG 119
Query: 283 YTPLHEAAIKGKIDVCIVLLQHGADPNIR 311
+TPLH A G ++ LL++GA+ R
Sbjct: 118 WTPLHATASCGFTEIARYLLENGANGGCR 32
Score = 55.8 bits (133), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 29/79 (36%), Positives = 43/79 (54%)
Frame = -1
Query: 856 LLEHGADVNAQDKGGLIPLHNAASYGHVDIAALLIKYNTCVNATDKWAFTPLHEAAQKGR 915
LLE GAD+N + GL LH A ++D+ L++ N V+ D +TPLH A G
Sbjct: 262 LLERGADINTANVDGLTALHQACIDDNLDMVEFLVEQNADVDVCDNEGWTPLHATASCGF 83
Query: 916 TQLCALLLAHGADPTMKNQ 934
T++ LL +GA+ + Q
Sbjct: 82 TEIARYLLENGANGGCRQQ 26
Score = 52.4 bits (124), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 28/76 (36%), Positives = 43/76 (56%)
Frame = -1
Query: 385 VQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAAS 444
V+ LL+ GAD++ + GL LH AC + ++ E L++ A V+ D +TPLH AS
Sbjct: 271 VKKLLERGADINTANVDGLTALHQACIDDNLDMVEFLVEQNADVDVCDNEGWTPLHATAS 92
Query: 445 KNRVEVCSLLLSHGAD 460
E+ LL +GA+
Sbjct: 91 CGFTEIARYLLENGAN 44
Score = 49.7 bits (117), Expect = 8e-06, Method: Compositional matrix adjust.
Identities = 31/90 (34%), Positives = 48/90 (53%), Gaps = 1/90 (1%)
Frame = -1
Query: 654 LLEASKAGDLETVKQLCS-SQNVNCRDLEGRHSTPLHFAAGYNRVSVVEYLLHHGADVHA 712
L A +GD + VK+L ++N +++G T LH A + + +VE+L+ ADV
Sbjct: 307 FLAACSSGDRDEVKKLLERGADINTANVDGL--TALHQACIDDNLDMVEFLVEQNADVDV 134
Query: 713 KDKGGLVPLHNACSYGHYEVAELLVRHGAS 742
D G PLH S G E+A L+ +GA+
Sbjct: 133 CDNEGWTPLHATASCGFTEIARYLLENGAN 44
Score = 47.0 bits (110), Expect = 5e-05, Method: Compositional matrix adjust.
Identities = 40/135 (29%), Positives = 60/135 (44%), Gaps = 1/135 (0%)
Frame = -1
Query: 293 GKIDVCIVLLQHGADPNIRNTDGKSALDLADPSAKAVLTGEYKKDELLEAARSGNEEKLM 352
G D C+V +++ L PSAK V + L A SG+ +++
Sbjct: 439 GAADECLVTKAPTGLKRWEDSETNRELGYPRPSAKKVKFQDGCV--FLAACSSGDRDEVK 266
Query: 353 ALLT-PLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACS 411
LL ++N DG T LH A + + +V+ L++ ADV D G PLH S
Sbjct: 265 KLLERGADINTANVDGL--TALHQACIDDNLDMVEFLVEQNADVDVCDNEGWTPLHATAS 92
Query: 412 YGHYEVTELLLKHGA 426
G E+ LL++GA
Sbjct: 91 CGFTEIARYLLENGA 47
Score = 47.0 bits (110), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 23/53 (43%), Positives = 32/53 (60%)
Frame = -1
Query: 839 TPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAALLIK 891
T LH A +NL++ E+L+E ADV+ D G PLH AS G +IA L++
Sbjct: 214 TALHQACIDDNLDMVEFLVEQNADVDVCDNEGWTPLHATASCGFTEIARYLLE 56
Score = 39.3 bits (90), Expect = 0.011, Method: Compositional matrix adjust.
Identities = 20/64 (31%), Positives = 34/64 (53%)
Frame = -1
Query: 724 ACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDG 783
ACS G + + L+ GA +N A++ T LH+A ++ + L++ AD + +G
Sbjct: 298 ACSSGDRDEVKKLLERGADINTANVDGLTALHQACIDDNLDMVEFLVEQNADVDVCDNEG 119
Query: 784 NTPL 787
TPL
Sbjct: 118 WTPL 107
Score = 37.7 bits (86), Expect = 0.035, Method: Compositional matrix adjust.
Identities = 22/64 (34%), Positives = 35/64 (54%)
Frame = -1
Query: 256 ACSFGHAEVVSLLLCQGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGADPNIRNTDG 315
ACS G + V LL +GAD N + T LH+A I +D+ L++ AD ++ + +G
Sbjct: 298 ACSSGDRDEVKKLLERGADINTANVDGLTALHQACIDDNLDMVEFLVEQNADVDVCDNEG 119
Query: 316 KSAL 319
+ L
Sbjct: 118 WTPL 107
Score = 33.1 bits (74), Expect = 0.76, Method: Compositional matrix adjust.
Identities = 17/62 (27%), Positives = 30/62 (48%)
Frame = -1
Query: 565 AAERAHNDVMEVLHKHGAKMNALDTLGQTALHRAALAGHLQTCRLLLSYGSDPSIISLQG 624
A D ++ L + GA +N + G TALH+A + +L L+ +D + +G
Sbjct: 298 ACSSGDRDEVKKLLERGADINTANVDGLTALHQACIDDNLDMVEFLVEQNADVDVCDNEG 119
Query: 625 FT 626
+T
Sbjct: 118 WT 113
Score = 32.3 bits (72), Expect = 1.3, Method: Compositional matrix adjust.
Identities = 17/62 (27%), Positives = 32/62 (51%)
Frame = -1
Query: 409 ACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHG 468
ACS G + + LL+ GA +N ++ T LH+A + +++ L+ AD + + G
Sbjct: 298 ACSSGDRDEVKKLLERGADINTANVDGLTALHQACIDDNLDMVEFLVEQNADVDVCDNEG 119
Query: 469 KS 470
+
Sbjct: 118 WT 113
Score = 30.8 bits (68), Expect = 3.4, Method: Compositional matrix adjust.
Identities = 22/64 (34%), Positives = 35/64 (54%), Gaps = 1/64 (1%)
Frame = -1
Query: 183 LRELLEACRNGDVSRVKRLVDA-ANVNAKDMAGRKSSPLHFAAGFGRKDVVEHLLQMGAN 241
L L +AC + ++ V+ LV+ A+V+ D G +PLH A G ++ +LL+ GAN
Sbjct: 217 LTALHQACIDDNLDMVEFLVEQNADVDVCDNEG--WTPLHATASCGFTEIARYLLENGAN 44
Query: 242 VHAR 245
R
Sbjct: 43 GGCR 32
Score = 29.6 bits (65), Expect = 9.0, Method: Compositional matrix adjust.
Identities = 18/64 (28%), Positives = 27/64 (42%)
Frame = -1
Query: 877 AASYGHVDIAALLIKYNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEG 936
A S G D L++ +N + T LH+A + L+ AD + + EG
Sbjct: 298 ACSSGDRDEVKKLLERGADINTANVDGLTALHQACIDDNLDMVEFLVEQNADVDVCDNEG 119
Query: 937 QTPL 940
TPL
Sbjct: 118 WTPL 107
>20792
Length = 441
Score = 57.4 bits (137), Expect = 4e-08, Method: Composition-based stats.
Identities = 37/99 (37%), Positives = 49/99 (49%), Gaps = 2/99 (2%)
Frame = +2
Query: 201 LVDAANVNAKDMAGRKSSPLHFAAGFGRKDVVEHLLQMGANVHARDDGGLIPLHNACSFG 260
L D ++ + G+K PLH A FG+ D + LLQ G V PL AC+
Sbjct: 38 LCDEVDLQIGNFEGKK--PLHETAQFGQLDCMNFLLQRGVQVDCLKRADWTPLMLACTKC 211
Query: 261 HAEVVSLLLCQGADPNA--RDNWNYTPLHEAAIKGKIDV 297
V+SLLL GADP +D WN H AA +G +D+
Sbjct: 212 QLPVISLLLKHGADPALVNKDGWN--SFHIAAREGHVDI 322
Score = 57.0 bits (136), Expect = 5e-08, Method: Composition-based stats.
Identities = 43/148 (29%), Positives = 64/148 (43%), Gaps = 2/148 (1%)
Frame = +2
Query: 386 QLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASK 445
Q L D+ + G PLH +G + LL+ G V+ + +TPL A +K
Sbjct: 29 QFSLCDEVDLQIGNFEGKKPLHETAQFGQLDCMNFLLQRGVQVDCLKRADWTPLMLACTK 208
Query: 446 NRVEVCSLLLSHGADPTLVNCHGKSAVDMAPTPELRERLTYEFKGHSLLQAAREADLAKV 505
++ V SLLL HGADP LVN G ++ + AARE + +
Sbjct: 209 CQLPVISLLLKHGADPALVNKDGWNSFHI---------------------AAREGHVDIL 325
Query: 506 KKTLALEIINFKQPQS--HETALHCAVA 531
K T LE + + QS T +C+ +
Sbjct: 326 KNTTGLECWSLECFQS**QNTTTYCSTS 409
Score = 54.3 bits (129), Expect = 3e-07, Method: Composition-based stats.
Identities = 33/104 (31%), Positives = 54/104 (51%), Gaps = 7/104 (6%)
Frame = +2
Query: 226 FGRKDVVEHL-------LQMGANVHARDDGGLIPLHNACSFGHAEVVSLLLCQGADPNAR 278
+GR+D++E LQ+G + G PLH FG + ++ LL +G +
Sbjct: 5 WGRRDLLEQFSLCDEVDLQIG------NFEGKKPLHETAQFGQLDCMNFLLQRGVQVDCL 166
Query: 279 DNWNYTPLHEAAIKGKIDVCIVLLQHGADPNIRNTDGKSALDLA 322
++TPL A K ++ V +LL+HGADP + N DG ++ +A
Sbjct: 167 KRADWTPLMLACTKCQLPVISLLLKHGADPALVNKDGWNSFHIA 298
Score = 53.9 bits (128), Expect = 4e-07, Method: Composition-based stats.
Identities = 30/90 (33%), Positives = 43/90 (47%), Gaps = 1/90 (1%)
Frame = +2
Query: 709 DVHAKDKGGLVPLHNACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAAAKGKYEICKL 768
D+ + G PLH +G + L++ G V+ +TPL A K + + L
Sbjct: 53 DLQIGNFEGKKPLHETAQFGQLDCMNFLLQRGVQVDCLKRADWTPLMLACTKCQLPVISL 232
Query: 769 LLKHGADPTKKNRDGNTPLDL-VKEGDTDI 797
LLKHGADP N+DG + +EG DI
Sbjct: 233 LLKHGADPALVNKDGWNSFHIAAREGHVDI 322
Score = 50.4 bits (119), Expect = 5e-06, Method: Composition-based stats.
Identities = 25/77 (32%), Positives = 40/77 (51%)
Frame = +2
Query: 870 GLIPLHNAASYGHVDIAALLIKYNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADP 929
G PLH A +G +D L++ V+ + +TPL A K + + +LLL HGADP
Sbjct: 77 GKKPLHETAQFGQLDCMNFLLQRGVQVDCLKRADWTPLMLACTKCQLPVISLLLKHGADP 256
Query: 930 TMKNQEGQTPLDLATAD 946
+ N++G +A +
Sbjct: 257 ALVNKDGWNSFHIAARE 307
Score = 47.8 bits (112), Expect = 3e-05, Method: Composition-based stats.
Identities = 30/106 (28%), Positives = 48/106 (45%)
Frame = +2
Query: 662 DLETVKQLCSSQNVNCRDLEGRHSTPLHFAAGYNRVSVVEYLLHHGADVHAKDKGGLVPL 721
DL LC ++ + EG+ PLH A + ++ + +LL G V + PL
Sbjct: 17 DLLEQFSLCDEVDLQIGNFEGK--KPLHETAQFGQLDCMNFLLQRGVQVDCLKRADWTPL 190
Query: 722 HNACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAAAKGKYEICK 767
AC+ V LL++HGA + + + H AA +G +I K
Sbjct: 191 MLACTKCQLPVISLLLKHGADPALVNKDGWNSFHIAAREGHVDILK 328
Score = 43.1 bits (100), Expect = 7e-04, Method: Composition-based stats.
Identities = 27/85 (31%), Positives = 41/85 (48%)
Frame = +2
Query: 366 DGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHG 425
+G+K PLH A + ++ + LLQ G V + PL AC+ V LLLKHG
Sbjct: 74 EGKK--PLHETAQFGQLDCMNFLLQRGVQVDCLKRADWTPLMLACTKCQLPVISLLLKHG 247
Query: 426 ACVNAMDLWQFTPLHEAASKNRVEV 450
A ++ + H AA + V++
Sbjct: 248 ADPALVNKDGWNSFHIAAREGHVDI 322
Score = 39.7 bits (91), Expect = 0.009, Method: Composition-based stats.
Identities = 23/47 (48%), Positives = 25/47 (53%)
Frame = +2
Query: 839 TPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDI 885
TPL LA L V LL+HGAD +K G H AA GHVDI
Sbjct: 182 TPLMLACTKCQLPVISLLLKHGADPALVNKDGWNSFHIAAREGHVDI 322
Score = 38.5 bits (88), Expect = 0.017, Method: Composition-based stats.
Identities = 24/84 (28%), Positives = 39/84 (46%), Gaps = 1/84 (1%)
Frame = +2
Query: 561 PLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTALHRAALAGHLQTCRLLLSYGSDPSII 620
PLH A+ D M L + G +++ L T L A L LLL +G+DP+++
Sbjct: 86 PLHETAQFGQLDCMNFLLQRGVQVDCLKRADWTPLMLACTKCQLPVISLLLKHGADPALV 265
Query: 621 SLQGFTAAQM-GNEAVQQILSEST 643
+ G+ + + E IL +T
Sbjct: 266 NKDGWNSFHIAAREGHVDILKNTT 337
Score = 36.6 bits (83), Expect = 0.073, Method: Composition-based stats.
Identities = 30/96 (31%), Positives = 47/96 (48%), Gaps = 2/96 (2%)
Frame = +2
Query: 511 LEIINF--KQPQSHETALHCAVASLHPKRKQVTELLLRKGANVNEKNKDFMTPLHVAAER 568
L+I NF K+P HETA + ++ LL++G V+ + TPL +A +
Sbjct: 56 LQIGNFEGKKPL-HETAQFGQLDCMN--------FLLQRGVQVDCLKRADWTPLMLACTK 208
Query: 569 AHNDVMEVLHKHGAKMNALDTLGQTALHRAALAGHL 604
V+ +L KHGA ++ G + H AA GH+
Sbjct: 209 CQLPVISLLLKHGADPALVNKDGWNSFHIAAREGHV 316
Score = 30.4 bits (67), Expect = 4.7, Method: Composition-based stats.
Identities = 14/36 (38%), Positives = 20/36 (55%)
Frame = +2
Query: 540 VTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVME 575
V LLL+ GA+ NKD H+AA H D+++
Sbjct: 221 VISLLLKHGADPALVNKDGWNSFHIAAREGHVDILK 328
>30978
Length = 566
Score = 54.3 bits (129), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 34/100 (34%), Positives = 49/100 (49%), Gaps = 1/100 (1%)
Frame = -2
Query: 857 LEHGADVNAQDKGGLIPLHNAASYGHVDIAALLIKYNTC-VNATDKWAFTPLHEAAQKGR 915
L + VN DK G PLH A GH+D +L+ C VN +K T LH AA K
Sbjct: 511 LSNRVSVNGLDKAGSTPLHWAGHGGHMDCLQVLLSEPKCEVNVQNKLGDTALHSAAWKNH 332
Query: 916 TQLCALLLAHGADPTMKNQEGQTPLDLATADDIRALLIDA 955
+ +LL GA ++N E + ++L ++ A+L A
Sbjct: 331 VEAVKMLLGKGARVDLRNNEKKLAVELTKDPEVAAMLRQA 212
Score = 53.5 bits (127), Expect = 5e-07, Method: Compositional matrix adjust.
Identities = 36/93 (38%), Positives = 46/93 (49%), Gaps = 1/93 (1%)
Frame = -2
Query: 389 LQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGAC-VNAMDLWQFTPLHEAASKNR 447
L + V+ DK G PLH A GH + ++LL C VN + T LH AA KN
Sbjct: 511 LSNRVSVNGLDKAGSTPLHWAGHGGHMDCLQVLLSEPKCEVNVQNKLGDTALHSAAWKNH 332
Query: 448 VEVCSLLLSHGADPTLVNCHGKSAVDMAPTPEL 480
VE +LL GA L N K AV++ PE+
Sbjct: 331 VEAVKMLLGKGARVDLRNNEKKLAVELTKDPEV 233
Score = 40.4 bits (93), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 29/81 (35%), Positives = 44/81 (54%), Gaps = 1/81 (1%)
Frame = -2
Query: 201 LVDAANVNAKDMAGRKSSPLHFAAGFGRKDVVEHLL-QMGANVHARDDGGLIPLHNACSF 259
L + +VN D AG S+PLH+A G D ++ LL + V+ ++ G LH+A
Sbjct: 511 LSNRVSVNGLDKAG--STPLHWAGHGGHMDCLQVLLSEPKCEVNVQNKLGDTALHSAAWK 338
Query: 260 GHAEVVSLLLCQGADPNARDN 280
H E V +LL +GA + R+N
Sbjct: 337 NHVEAVKMLLGKGARVDLRNN 275
Score = 38.1 bits (87), Expect = 0.023, Method: Compositional matrix adjust.
Identities = 24/77 (31%), Positives = 40/77 (51%), Gaps = 1/77 (1%)
Frame = -2
Query: 670 CSSQNVNCRDLEGRHSTPLHFAAGYNRVSVVEYLLHH-GADVHAKDKGGLVPLHNACSYG 728
C S V+ L+ STPLH+A + ++ LL +V+ ++K G LH+A
Sbjct: 514 CLSNRVSVNGLDKAGSTPLHWAGHGGHMDCLQVLLSEPKCEVNVQNKLGDTALHSAAWKN 335
Query: 729 HYEVAELLVRHGASVNV 745
H E ++L+ GA V++
Sbjct: 334 HVEAVKMLLGKGARVDL 284
Score = 35.4 bits (80), Expect = 0.14, Method: Compositional matrix adjust.
Identities = 22/69 (31%), Positives = 34/69 (49%), Gaps = 1/69 (1%)
Frame = -2
Query: 823 CTPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLL-EHGADVNAQDKGGLIPLHNAASYG 881
C ++ STPLH A +++ + LL E +VN Q+K G LH+AA
Sbjct: 514 CLSNRVSVNGLDKAGSTPLHWAGHGGHMDCLQVLLSEPKCEVNVQNKLGDTALHSAAWKN 335
Query: 882 HVDIAALLI 890
HV+ +L+
Sbjct: 334 HVEAVKMLL 308
>15359
Length = 780
Score = 53.1 bits (126), Expect = 8e-07, Method: Compositional matrix adjust.
Identities = 32/72 (44%), Positives = 41/72 (56%), Gaps = 2/72 (2%)
Frame = +1
Query: 249 GLIPLHNACSFGHAEVVSLLLCQ-GADPNARDNWNYTPLHEAAIKGKIDVCIVLLQ-HGA 306
G LH A FG EVV +L + G + N R + YTPLH AAI G D+ +L+ + A
Sbjct: 349 GYTALHWAAKFGKPEVVKMLANKIGVEINQRSHGGYTPLHLAAIHGHEDIIELLVTGYKA 528
Query: 307 DPNIRNTDGKSA 318
D NIR+ GK A
Sbjct: 529 DANIRDYSGKKA 564
Score = 50.1 bits (118), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 34/100 (34%), Positives = 54/100 (54%), Gaps = 4/100 (4%)
Frame = +1
Query: 184 RELLEACRNGDVSRVKRLVD--AANVNAKDMAGRKSSPLHFAAGFGRKDVVEHLL-QMGA 240
+E + D + RL++ A KD+A ++ LH+AA FG+ +VV+ L ++G
Sbjct: 250 KEWMLVSATADYHEMFRLLNKNARLAKVKDIANGYTA-LHWAAKFGKPEVVKMLANKIGV 426
Query: 241 NVHARDDGGLIPLHNACSFGHAEVVSLLLC-QGADPNARD 279
++ R GG PLH A GH +++ LL+ AD N RD
Sbjct: 427 EINQRSHGGYTPLHLAAIHGHEDIIELLVTGYKADANIRD 546
Score = 43.5 bits (101), Expect = 6e-04, Method: Compositional matrix adjust.
Identities = 24/64 (37%), Positives = 38/64 (59%), Gaps = 2/64 (3%)
Frame = +1
Query: 686 TPLHFAAGYNRVSVVEYLLHH-GADVHAKDKGGLVPLHNACSYGHYEVAELLVR-HGASV 743
T LH+AA + + VV+ L + G +++ + GG PLH A +GH ++ ELLV + A
Sbjct: 355 TALHWAAKFGKPEVVKMLANKIGVEINQRSHGGYTPLHLAAIHGHEDIIELLVTGYKADA 534
Query: 744 NVAD 747
N+ D
Sbjct: 535 NIRD 546
Score = 42.4 bits (98), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 26/64 (40%), Positives = 33/64 (51%), Gaps = 2/64 (3%)
Frame = +1
Query: 839 TPLHLAAGYNNLEVAEYLLEH-GADVNAQDKGGLIPLHNAASYGHVDIAALLIK-YNTCV 896
T LH AA + EV + L G ++N + GG PLH AA +GH DI LL+ Y
Sbjct: 355 TALHWAAKFGKPEVVKMLANKIGVEINQRSHGGYTPLHLAAIHGHEDIIELLVTGYKADA 534
Query: 897 NATD 900
N D
Sbjct: 535 NIRD 546
Score = 41.2 bits (95), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 19/53 (35%), Positives = 32/53 (60%), Gaps = 1/53 (1%)
Frame = +1
Query: 371 TPLHLAAGYNRVRIVQLLLQH-GADVHAKDKGGLVPLHNACSYGHYEVTELLL 422
T LH AA + + +V++L G +++ + GG PLH A +GH ++ ELL+
Sbjct: 355 TALHWAAKFGKPEVVKMLANKIGVEINQRSHGGYTPLHLAAIHGHEDIIELLV 513
Score = 37.4 bits (85), Expect = 0.043, Method: Compositional matrix adjust.
Identities = 26/73 (35%), Positives = 39/73 (53%), Gaps = 2/73 (2%)
Frame = +1
Query: 524 TALHCAVASLHPKRKQVTELLLRK-GANVNEKNKDFMTPLHVAAERAHNDVMEVL-HKHG 581
TALH A P +V ++L K G +N+++ TPLH+AA H D++E+L +
Sbjct: 355 TALHWAAKFGKP---EVVKMLANKIGVEINQRSHGGYTPLHLAAIHGHEDIIELLVTGYK 525
Query: 582 AKMNALDTLGQTA 594
A N D G+ A
Sbjct: 526 ADANIRDYSGKKA 564
>34789
Length = 1249
Score = 52.4 bits (124), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 49/202 (24%), Positives = 90/202 (44%)
Frame = +3
Query: 578 HKHGAKMNALDTLGQTALHRAALAGHLQTCRLLLSYGSDPSIISLQGFTAAQMGNEAVQQ 637
H +N + + G TAL A G+++ LL G++P ++Q GN
Sbjct: 39 HSVAHFLNQMGSDGSTALFMAVYDGNVELVDYLLKNGANPHF-------SSQHGNFLHAA 197
Query: 638 ILSESTPIRTSDVDYRLLEASKAGDLETVKQLCSSQNVNCRDLEGRHSTPLHFAAGYNRV 697
+LS+S P+ +A DL ++N ++ G ++PL + +
Sbjct: 198 VLSQSVPL-----------IQRALDLGC--------DINEHNMFG--NSPLTLVSRLDLP 314
Query: 698 SVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGASVNVADLWKFTPLHEA 757
L+ HGAD++++D+ PL + +G A LL++HGAS+++ D + ++ +
Sbjct: 315 EACRMLVEHGADLNSRDRYRETPLLASVYFGCELNARLLIQHGASLDLVDDNHTSAIYWS 494
Query: 758 AAKGKYEICKLLLKHGADPTKK 779
+ LLL GA T +
Sbjct: 495 IFNNRQRTLMLLLLAGASFTPQ 560
Score = 47.0 bits (110), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 41/179 (22%), Positives = 77/179 (43%)
Frame = +3
Query: 284 TPLHEAAIKGKIDVCIVLLQHGADPNIRNTDGKSALDLADPSAKAVLTGEYKKDELLEAA 343
T L A G +++ LL++GA+P+ + G L AA
Sbjct: 84 TALFMAVYDGNVELVDYLLKNGANPHFSSQHGN----------------------FLHAA 197
Query: 344 RSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGL 403
L+ L + + + ++PL L + + ++L++HGAD++++D+
Sbjct: 198 VLSQSVPLIQRALDLGCDINEHNMFGNSPLTLVSRLDLPEACRMLVEHGADLNSRDRYRE 377
Query: 404 VPLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPT 462
PL + +G LL++HGA ++ +D + ++ + NR LLL GA T
Sbjct: 378 TPLLASVYFGCELNARLLIQHGASLDLVDDNHTSAIYWSIFNNRQRTLMLLLLAGASFT 554
Score = 43.1 bits (100), Expect = 8e-04, Method: Compositional matrix adjust.
Identities = 42/148 (28%), Positives = 61/148 (41%)
Frame = +3
Query: 648 SDVDYRLLEASKAGDLETVKQLCSSQNVNCRDLEGRHSTPLHFAAGYNRVSVVEYLLHHG 707
SD L A G++E V L +N +H LH A V +++ L G
Sbjct: 72 SDGSTALFMAVYDGNVELVDYLL--KNGANPHFSSQHGNFLHAAVLSQSVPLIQRALDLG 245
Query: 708 ADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAAAKGKYEICK 767
D++ + G PL E +LV HGA +N D ++ TPL + G +
Sbjct: 246 CDINEHNMFGNSPLTLVSRLDLPEACRMLVEHGADLNSRDRYRETPLLASVYFGCELNAR 425
Query: 768 LLLKHGADPTKKNRDGNTPLDLVKEGDT 795
LL++HGA LDLV + T
Sbjct: 426 LLIQHGAS-----------LDLVDDNHT 476
Score = 42.0 bits (97), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 46/180 (25%), Positives = 76/180 (42%), Gaps = 1/180 (0%)
Frame = +3
Query: 752 TPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPLDLVKEGDTDIQXXXXXXXXXXXXX 811
T L A G E+ LLK+GA+P ++ GN V +
Sbjct: 84 TALFMAVYDGNVELVDYLLKNGANPHFSSQHGNFLHAAVLSQSVPL-------------- 221
Query: 812 XXXXXXRVQK-LCTPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGG 870
+Q+ L +IN + G ++PL L + + E L+EHGAD+N++D+
Sbjct: 222 -------IQRALDLGCDINEHNMFG--NSPLTLVSRLDLPEACRMLVEHGADLNSRDRYR 374
Query: 871 LIPLHNAASYGHVDIAALLIKYNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPT 930
PL + +G A LLI++ ++ D + ++ + R + LLL GA T
Sbjct: 375 ETPLLASVYFGCELNARLLIQHGASLDLVDDNHTSAIYWSIFNNRQRTLMLLLLAGASFT 554
Score = 40.8 bits (94), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 28/103 (27%), Positives = 52/103 (50%)
Frame = +3
Query: 838 STPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAALLIKYNTCVN 897
ST L +A N+E+ +YLL++GA+ + + G LH A V + + +N
Sbjct: 81 STALFMAVYDGNVELVDYLLKNGANPHFSSQHGNF-LHAAVLSQSVPLIQRALDLGCDIN 257
Query: 898 ATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTPL 940
+ + +PL ++ + C +L+ HGAD +++ +TPL
Sbjct: 258 EHNMFGNSPLTLVSRLDLPEACRMLVEHGADLNSRDRYRETPL 386
Score = 37.4 bits (85), Expect = 0.039, Method: Compositional matrix adjust.
Identities = 36/135 (26%), Positives = 62/135 (45%), Gaps = 1/135 (0%)
Frame = +3
Query: 186 LLEACRNGDVSRVKRLV-DAANVNAKDMAGRKSSPLHFAAGFGRKDVVEHLLQMGANVHA 244
L A +G+V V L+ + AN + G + LH A +++ L +G +++
Sbjct: 90 LFMAVYDGNVELVDYLLKNGANPHFSSQHG---NFLHAAVLSQSVPLIQRALDLGCDINE 260
Query: 245 RDDGGLIPLHNACSFGHAEVVSLLLCQGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQH 304
+ G PL E +L+ GAD N+RD + TPL + G +L+QH
Sbjct: 261 HNMFGNSPLTLVSRLDLPEACRMLVEHGADLNSRDRYRETPLLASVYFGCELNARLLIQH 440
Query: 305 GADPNIRNTDGKSAL 319
GA ++ + + SA+
Sbjct: 441 GASLDLVDDNHTSAI 485
Score = 33.9 bits (76), Expect = 0.43, Method: Compositional matrix adjust.
Identities = 26/99 (26%), Positives = 46/99 (46%)
Frame = +3
Query: 522 HETALHCAVASLHPKRKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHG 581
H LH AV S + + + L G ++NE N +PL + + + +L +HG
Sbjct: 174 HGNFLHAAVLS---QSVPLIQRALDLGCDINEHNMFGNSPLTLVSRLDLPEACRMLVEHG 344
Query: 582 AKMNALDTLGQTALHRAALAGHLQTCRLLLSYGSDPSII 620
A +N+ D +T L + G RLL+ +G+ ++
Sbjct: 345 ADLNSRDRYRETPLLASVYFGCELNARLLIQHGASLDLV 461
>38834
Length = 496
Score = 52.4 bits (124), Expect = 1e-06, Method: Composition-based stats.
Identities = 25/66 (37%), Positives = 38/66 (57%)
Frame = -1
Query: 724 ACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDG 783
ACS GH ++AE+L R G +NV ++ +TP H + K++I L+K A+ N G
Sbjct: 493 ACSSGHLDIAEMLHRRGVQINVVNINGYTPXHLSVYFNKFDITHFLVKINAEINTVNNAG 314
Query: 784 NTPLDL 789
TP+ L
Sbjct: 313 QTPVYL 296
Score = 48.9 bits (115), Expect = 1e-05, Method: Composition-based stats.
Identities = 24/84 (28%), Positives = 43/84 (51%)
Frame = -1
Query: 843 LAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAALLIKYNTCVNATDKW 902
+A +L++AE L G +N + G P H + + DI L+K N +N +
Sbjct: 496 IACSSGHLDIAEMLHRRGVQINVVNINGYTPXHLSVYFNKFDITHFLVKINAEINTVNNA 317
Query: 903 AFTPLHEAAQKGRTQLCALLLAHG 926
TP++ AA +G +++ AL++ G
Sbjct: 316 GQTPVYLAALRGNSKILALMVNAG 245
Score = 43.9 bits (102), Expect = 4e-04, Method: Composition-based stats.
Identities = 23/75 (30%), Positives = 42/75 (56%)
Frame = -1
Query: 540 VTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTALHRAA 599
+ E+L R+G +N N + TP H++ D+ L K A++N ++ GQT ++ AA
Sbjct: 469 IAEMLHRRGVQINVVNINGYTPXHLSVYFNKFDITHFLVKINAEINTVNNAGQTPVYLAA 290
Query: 600 LAGHLQTCRLLLSYG 614
L G+ + L+++ G
Sbjct: 289 LRGNSKILALMVNAG 245
Score = 43.5 bits (101), Expect = 5e-04, Method: Composition-based stats.
Identities = 20/67 (29%), Positives = 38/67 (56%)
Frame = -1
Query: 409 ACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHG 468
ACS GH ++ E+L + G +N +++ +TP H + N+ ++ L+ A+ VN G
Sbjct: 493 ACSSGHLDIAEMLHRRGVQINVVNINGYTPXHLSVYFNKFDITHFLVKINAEINTVNNAG 314
Query: 469 KSAVDMA 475
++ V +A
Sbjct: 313 QTPVYLA 293
Score = 40.0 bits (92), Expect = 0.007, Method: Composition-based stats.
Identities = 25/82 (30%), Positives = 40/82 (48%), Gaps = 3/82 (3%)
Frame = -1
Query: 877 AASYGHVDIAALLIKYNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEG 936
A S GH+DIA +L + +N + +TP H + + + L+ A+ N G
Sbjct: 493 ACSSGHLDIAEMLHRRGVQINVVNINGYTPXHLSVYFNKFDITHFLVKINAEINTVNNAG 314
Query: 937 QTPLDLATA---DDIRALLIDA 955
QTP+ LA I AL+++A
Sbjct: 313 QTPVYLAALRGNSKILALMVNA 248
Score = 37.7 bits (86), Expect = 0.032, Method: Composition-based stats.
Identities = 21/87 (24%), Positives = 40/87 (45%)
Frame = -1
Query: 223 AAGFGRKDVVEHLLQMGANVHARDDGGLIPLHNACSFGHAEVVSLLLCQGADPNARDNWN 282
A G D+ E L + G ++ + G P H + F ++ L+ A+ N +N
Sbjct: 493 ACSSGHLDIAEMLHRRGVQINVVNINGYTPXHLSVYFNKFDITHFLVKINAEINTVNNAG 314
Query: 283 YTPLHEAAIKGKIDVCIVLLQHGADPN 309
TP++ AA++G + +++ G N
Sbjct: 313 QTPVYLAALRGNSKILALMVNAGCKVN 233
Score = 37.7 bits (86), Expect = 0.034, Method: Composition-based stats.
Identities = 19/83 (22%), Positives = 38/83 (45%)
Frame = -1
Query: 691 AAGYNRVSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGASVNVADLWK 750
A + + E L G ++ + G P H + + +++ LV+ A +N +
Sbjct: 493 ACSSGHLDIAEMLHRRGVQINVVNINGYTPXHLSVYFNKFDITHFLVKINAEINTVNNAG 314
Query: 751 FTPLHEAAAKGKYEICKLLLKHG 773
TP++ AA +G +I L++ G
Sbjct: 313 QTPVYLAALRGNSKILALMVNAG 245
Score = 37.4 bits (85), Expect = 0.042, Method: Composition-based stats.
Identities = 21/67 (31%), Positives = 34/67 (50%)
Frame = -1
Query: 256 ACSFGHAEVVSLLLCQGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGADPNIRNTDG 315
ACS GH ++ +L +G N + YTP H + K D+ L++ A+ N N G
Sbjct: 493 ACSSGHLDIAEMLHRRGVQINVVNINGYTPXHLSVYFNKFDITHFLVKINAEINTVNNAG 314
Query: 316 KSALDLA 322
++ + LA
Sbjct: 313 QTPVYLA 293
Score = 37.0 bits (84), Expect = 0.060, Method: Composition-based stats.
Identities = 18/84 (21%), Positives = 44/84 (52%)
Frame = -1
Query: 375 LAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGACVNAMDLW 434
+A + I ++L + G ++ + G P H + + +++T L+K A +N ++
Sbjct: 496 IACSSGHLDIAEMLHRRGVQINVVNINGYTPXHLSVYFNKFDITHFLVKINAEINTVNNA 317
Query: 435 QFTPLHEAASKNRVEVCSLLLSHG 458
TP++ AA + ++ +L+++ G
Sbjct: 316 GQTPVYLAALRGNSKILALMVNAG 245
>20036
Length = 1849
Score = 52.0 bits (123), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 37/109 (33%), Positives = 55/109 (50%), Gaps = 2/109 (1%)
Frame = +3
Query: 198 VKRLVDAANVNA-KDMAGRKSSPLHFAAGFGRKDVVEHLLQMGANVHARDDGGLIPLHNA 256
+++L A ++NA + G+ + L A R D+VE LL+ GA+ + +D G L A
Sbjct: 1050 IRQLFLAGDINACAEQTGQ--TALMLATSQCRTDMVELLLETGADCNQQDFDGSTALMCA 1223
Query: 257 CSFGHAEVVSLLLCQ-GADPNARDNWNYTPLHEAAIKGKIDVCIVLLQH 304
C GH +V LLL Q D DN N T L A D+ ++L +H
Sbjct: 1224 CEHGHTAIVQLLLAQPHCDATLTDNENSTALSIAMEASHKDIGVILYKH 1370
Score = 44.3 bits (103), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 23/57 (40%), Positives = 31/57 (54%)
Frame = +3
Query: 371 TPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGAC 427
T L LA R +V+LLL+ GAD + +D G L AC +GH + +LLL C
Sbjct: 1107 TALMLATSQCRTDMVELLLETGADCNQQDFDGSTALMCACEHGHTAIVQLLLAQPHC 1277
Score = 43.1 bits (100), Expect = 8e-04, Method: Compositional matrix adjust.
Identities = 52/192 (27%), Positives = 75/192 (39%), Gaps = 9/192 (4%)
Frame = +3
Query: 743 VNVADLWKFTPLHEAAAKGKYEICKLLLK-HGADPTKKNRDGNTP-----LDLVKEGD-T 795
VN+ D + +H + ++I LLL D + N+ G TP L ++ D
Sbjct: 864 VNLVDSNGNSAIHYCVSHCNFDIVGLLLDTEVCDVKRPNKAGYTPTMLASLAFIQNDDHR 1043
Query: 796 DIQXXXXXXXXXXXXXXXXXXXRVQKLCTPENIN-CRDTQGRNSTPLHLAAGYNNLEVAE 854
DI +++L +IN C + G+ T L LA ++ E
Sbjct: 1044 DI---------------------IRQLFLAGDINACAEQTGQ--TALMLATSQCRTDMVE 1154
Query: 855 YLLEHGADVNAQDKGGLIPLHNAASYGHVDIAALLIKYNTC-VNATDKWAFTPLHEAAQK 913
LLE GAD N QD G L A +GH I LL+ C TD T L A +
Sbjct: 1155 LLLETGADCNQQDFDGSTALMCACEHGHTAIVQLLLAQPHCDATLTDNENSTALSIAMEA 1334
Query: 914 GRTQLCALLLAH 925
+ +L H
Sbjct: 1335 SHKDIGVILYKH 1370
Score = 42.7 bits (99), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 38/135 (28%), Positives = 58/135 (42%), Gaps = 8/135 (5%)
Frame = +3
Query: 664 ETVKQLCSSQNVN-CRDLEGRHSTPLHFAAGYNRVSVVEYLLHHGADVHAKDKGGLVPLH 722
+ ++QL + ++N C + G+ T L A R +VE LL GAD + +D G L
Sbjct: 1044 DIIRQLFLAGDINACAEQTGQ--TALMLATSQCRTDMVELLLETGADCNQQDFDGSTALM 1217
Query: 723 NACSYGHYEVAELLVRHG-ASVNVADLWKFTPLHEAAAKGKYEICKLLLKH------GAD 775
AC +GH + +LL+ + D T L A +I +L KH G
Sbjct: 1218 CACEHGHTAIVQLLLAQPHCDATLTDNENSTALSIAMEASHKDIGVILYKHLNFSSPGFQ 1397
Query: 776 PTKKNRDGNTPLDLV 790
+K+ TP L
Sbjct: 1398 KKRKSSSSPTPRTLT 1442
Score = 33.5 bits (75), Expect = 0.54, Method: Compositional matrix adjust.
Identities = 34/122 (27%), Positives = 52/122 (42%), Gaps = 9/122 (7%)
Frame = +3
Query: 828 INCRDTQGRNSTPLHLAAGYNNLEVAEYLLE-HGADVNAQDKGGLIPLHNAA-----SYG 881
+N D+ G ++ +H + N ++ LL+ DV +K G P A+ +
Sbjct: 864 VNLVDSNG--NSAIHYCVSHCNFDIVGLLLDTEVCDVKRPNKAGYTPTMLASLAFIQNDD 1037
Query: 882 HVDIAALLI---KYNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQT 938
H DI L N C T + T L A + RT + LLL GAD ++ +G T
Sbjct: 1038HRDIIRQLFLAGDINACAEQTGQ---TALMLATSQCRTDMVELLLETGADCNQQDFDGST 1208
Query: 939 PL 940
L
Sbjct: 1209AL 1214
Score = 33.1 bits (74), Expect = 0.83, Method: Compositional matrix adjust.
Identities = 25/76 (32%), Positives = 37/76 (48%), Gaps = 1/76 (1%)
Frame = +3
Query: 560 TPLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTALHRAALAGHLQTCRLLLSY-GSDPS 618
T L +A + D++E+L + GA N D G TAL A GH +LLL+ D +
Sbjct: 1107 TALMLATSQCRTDMVELLLETGADCNQQDFDGSTALMCACEHGHTAIVQLLLAQPHCDAT 1286
Query: 619 IISLQGFTAAQMGNEA 634
+ + TA + EA
Sbjct: 1287 LTDNENSTALSIAMEA 1334
Score = 30.8 bits (68), Expect = 3.4, Method: Compositional matrix adjust.
Identities = 53/192 (27%), Positives = 72/192 (37%), Gaps = 9/192 (4%)
Frame = +3
Query: 242 VHARDDGGLIPLHNACSFGHAEVVSLLL----CQGADPNARDNWNYTPLHEAAIKGKIDV 297
V+ D G +H S + ++V LLL C PN YTP A++
Sbjct: 864 VNLVDSNGNSAIHYCVSHCNFDIVGLLLDTEVCDVKRPNKA---GYTPTMLASLAF---- 1022
Query: 298 CIVLLQHGADPNIRNTDGKS---ALDLA-DPSAKAVLTGEYKKDELLEAARSGNEEKLMA 353
I+N D + L LA D +A A TG+ L A S ++
Sbjct: 1023 ------------IQNDDHRDIIRQLFLAGDINACAEQTGQTA----LMLATSQCRTDMVE 1154
Query: 354 LLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLL-QHGADVHAKDKGGLVPLHNACSY 412
LL +C+ D ST L A + IVQLLL Q D D L A
Sbjct: 1155 LLLETGADCNQQDFDGSTALMCACEHGHTAIVQLLLAQPHCDATLTDNENSTALSIAMEA 1334
Query: 413 GHYEVTELLLKH 424
H ++ +L KH
Sbjct: 1335 SHKDIGVILYKH 1370
Score = 30.0 bits (66), Expect = 6.9, Method: Compositional matrix adjust.
Identities = 29/106 (27%), Positives = 44/106 (41%), Gaps = 1/106 (0%)
Frame = +3
Query: 218 SPLHFAAGFGRKDVVEHLLQMGANVHARDDGGLIPLHNACSFGHAEVVSLLLCQGADPNA 277
+ L F +D++ L G + G L A S ++V LLL GAD N
Sbjct: 1008 ASLAFIQNDDHRDIIRQLFLAGDINACAEQTGQTALMLATSQCRTDMVELLLETGADCNQ 1187
Query: 278 RDNWNYTPLHEAAIKGKIDVCIVLL-QHGADPNIRNTDGKSALDLA 322
+D T L A G + +LL Q D + + + +AL +A
Sbjct: 1188 QDFDGSTALMCACEHGHTAIVQLLLAQPHCDATLTDNENSTALSIA 1325
>12417
Length = 954
Score = 51.6 bits (122), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 29/72 (40%), Positives = 41/72 (56%)
Frame = +2
Query: 215 RKSSPLHFAAGFGRKDVVEHLLQMGANVHARDDGGLIPLHNACSFGHAEVVSLLLCQGAD 274
R S L AA G + L+Q GA+V++ + G PLH A + GH +V LLL +GAD
Sbjct: 230 RASVALAMAANRGLDKMCSQLIQTGADVNSATEHGRTPLHXASAQGHGHIVDLLLEKGAD 409
Query: 275 PNARDNWNYTPL 286
+A D++ T L
Sbjct: 410 IDAEDDYGDTAL 445
Score = 47.0 bits (110), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 25/65 (38%), Positives = 38/65 (58%)
Frame = +2
Query: 368 RKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGAC 427
R S L +AA ++ L+Q GADV++ + G PLH A + GH + +LLL+ GA
Sbjct: 230 RASVALAMAANRGLDKMCSQLIQTGADVNSATEHGRTPLHXASAQGHGHIVDLLLEKGAD 409
Query: 428 VNAMD 432
++A D
Sbjct: 410 IDAED 424
Score = 45.1 bits (105), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 34/102 (33%), Positives = 48/102 (47%), Gaps = 2/102 (1%)
Frame = +2
Query: 680 LEGRHSTPLHFAAGYNRVSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRH 739
LE R S L AA + L+ GADV++ + G PLH A + GH + +LL+
Sbjct: 221 LEERASVALAMAANRGLDKMCSQLIQTGADVNSATEHGRTPLHXASAQGHGHIVDLLLEK 400
Query: 740 GASVNVADLWKFTPLHEAAAKGKYEIC--KLLLKHGADPTKK 779
GA ++ D + T L A G ++ C L L H KK
Sbjct: 401 GADIDAEDDYGDTALSIADQFG-FKSCGRXLFLFHWQQRAKK 523
Score = 44.7 bits (104), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 28/79 (35%), Positives = 42/79 (53%)
Frame = +2
Query: 836 RNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAALLIKYNTC 895
R S L +AA ++ L++ GADVN+ + G PLH A++ GH I LL++
Sbjct: 230 RASVALAMAANRGLDKMCSQLIQTGADVNSATEHGRTPLHXASAQGHGHIVDLLLEKGAD 409
Query: 896 VNATDKWAFTPLHEAAQKG 914
++A D + T L A Q G
Sbjct: 410 IDAEDDYGDTALSIADQFG 466
Score = 42.4 bits (98), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 24/70 (34%), Positives = 38/70 (54%)
Frame = +2
Query: 544 LLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTALHRAALAGH 603
L++ GA+VN + TPLH A+ + H ++++L + GA ++A D G TAL A G
Sbjct: 290 LIQTGADVNSATEHGRTPLHXASAQGHGHIVDLLLEKGADIDAEDDYGDTALSIADQFGF 469
Query: 604 LQTCRLLLSY 613
R L +
Sbjct: 470 KSCGRXLFLF 499
Score = 40.4 bits (93), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 25/73 (34%), Positives = 40/73 (54%)
Frame = +2
Query: 251 IPLHNACSFGHAEVVSLLLCQGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGADPNI 310
+ L A + G ++ S L+ GAD N+ TPLH A+ +G + +LL+ GAD +
Sbjct: 239 VALAMAANRGLDKMCSQLIQTGADVNSATEHGRTPLHXASAQGHGHIVDLLLEKGADIDA 418
Query: 311 RNTDGKSALDLAD 323
+ G +AL +AD
Sbjct: 419 EDDYGDTALSIAD 457
Score = 40.0 bits (92), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 27/74 (36%), Positives = 40/74 (54%)
Frame = +2
Query: 719 VPLHNACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAAAKGKYEICKLLLKHGADPTK 778
V L A + G ++ L++ GA VN A TPLH A+A+G I LLL+ GAD
Sbjct: 239 VALAMAANRGLDKMCSQLIQTGADVNSATEHGRTPLHXASAQGHGHIVDLLLEKGADIDA 418
Query: 779 KNRDGNTPLDLVKE 792
++ G+T L + +
Sbjct: 419 EDDYGDTALSIADQ 460
Score = 38.5 bits (88), Expect = 0.018, Method: Compositional matrix adjust.
Identities = 47/158 (29%), Positives = 68/158 (43%), Gaps = 3/158 (1%)
Frame = +2
Query: 259 FGHAEVVSLLLCQGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGADPNIRN-TDGKS 317
H +V S + GA + R +T L EA + +D ++L + N T+ +S
Sbjct: 20 LDHTDVRSNDIVPGATLHMRVWPMWTSLVEAVAQNDVDHVMML-------GVTNPTEYRS 178
Query: 318 A-LDLADPSAKAVLTGEYKKDELLEAARSGNEEKLMALL-TPLNVNCHASDGRKSTPLHL 375
D A+ E L AA G ++ L+ T +VN GR TPLH
Sbjct: 179 PNSDYMTKRARKAWLEERASVALAMAANRGLDKMCSQLIQTGADVNSATEHGR--TPLHX 352
Query: 376 AAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYG 413
A+ IV LLL+ GAD+ A+D G L A +G
Sbjct: 353 ASAQGHGHIVDLLLEKGADIDAEDDYGDTALSIADQFG 466
Score = 37.4 bits (85), Expect = 0.041, Method: Compositional matrix adjust.
Identities = 24/72 (33%), Positives = 37/72 (51%)
Frame = +2
Query: 872 IPLHNAASYGHVDIAALLIKYNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTM 931
+ L AA+ G + + LI+ VN+ + TPLH A+ +G + LLL GAD
Sbjct: 239 VALAMAANRGLDKMCSQLIQTGADVNSATEHGRTPLHXASAQGHGHIVDLLLEKGADIDA 418
Query: 932 KNQEGQTPLDLA 943
++ G T L +A
Sbjct: 419 EDDYGDTALSIA 454
Score = 34.3 bits (77), Expect = 0.33, Method: Compositional matrix adjust.
Identities = 23/72 (31%), Positives = 38/72 (52%)
Frame = +2
Query: 404 VPLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTL 463
V L A + G ++ L++ GA VN+ TPLH A+++ + LLL GAD
Sbjct: 239 VALAMAANRGLDKMCSQLIQTGADVNSATEHGRTPLHXASAQGHGHIVDLLLEKGADIDA 418
Query: 464 VNCHGKSAVDMA 475
+ +G +A+ +A
Sbjct: 419 EDDYGDTALSIA 454
Score = 33.1 bits (74), Expect = 0.76, Method: Compositional matrix adjust.
Identities = 23/72 (31%), Positives = 35/72 (48%)
Frame = +2
Query: 562 LHVAAERAHNDVMEVLHKHGAKMNALDTLGQTALHRAALAGHLQTCRLLLSYGSDPSIIS 621
L +AA R + + L + GA +N+ G+T LH A+ GH LLL G+D
Sbjct: 245 LAMAANRGLDKMCSQLIQTGADVNSATEHGRTPLHXASAQGHGHIVDLLLEKGADIDAED 424
Query: 622 LQGFTAAQMGNE 633
G TA + ++
Sbjct: 425 DYGDTALSIADQ 460
Score = 30.0 bits (66), Expect = 5.7, Method: Compositional matrix adjust.
Identities = 14/36 (38%), Positives = 22/36 (61%)
Frame = +2
Query: 910 AAQKGRTQLCALLLAHGADPTMKNQEGQTPLDLATA 945
AA +G ++C+ L+ GAD + G+TPL A+A
Sbjct: 254 AANRGLDKMCSQLIQTGADVNSATEHGRTPLHXASA 361
>27067
Length = 409
Score = 51.6 bits (122), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 35/118 (29%), Positives = 57/118 (48%), Gaps = 9/118 (7%)
Frame = +1
Query: 341 EAARSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDK 400
EA + N + L LLT + C+A + + TP+ AA R+ + +LL HG + ++
Sbjct: 43 EAIKVNNTDILRYLLTVPGLECNAVNASQKTPVMEAASRGRIECLTMLLDHGCNTEGENI 222
Query: 401 GGLVPLHN---ACSYGHYEV------TELLLKHGACVNAMDLWQFTPLHEAASKNRVE 449
G +H+ +C G E+ +L+ K G +NA D + +PLH A S E
Sbjct: 223 RGKTAMHHCLLSCG-GFVEIEDMVTCMDLVYKAGGNINAQDWFGTSPLHLAISTENFE 393
Score = 43.9 bits (102), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 29/81 (35%), Positives = 46/81 (56%), Gaps = 1/81 (1%)
Frame = +1
Query: 393 ADVHAKDKGGLVPLHNACSYGHYEVTELLLK-HGACVNAMDLWQFTPLHEAASKNRVEVC 451
AD+++K KG +H A + ++ LL G NA++ Q TP+ EAAS+ R+E
Sbjct: 1 ADINSKFKGS-SAVHEAIKVNNTDILRYLLTVPGLECNAVNASQKTPVMEAASRGRIECL 177
Query: 452 SLLLSHGADPTLVNCHGKSAV 472
++LL HG + N GK+A+
Sbjct: 178 TMLLDHGCNTEGENIRGKTAM 240
Score = 43.5 bits (101), Expect = 6e-04, Method: Compositional matrix adjust.
Identities = 28/118 (23%), Positives = 54/118 (45%), Gaps = 9/118 (7%)
Frame = +1
Query: 656 EASKAGDLETVKQLCSSQNVNCRDLEGRHSTPLHFAAGYNRVSVVEYLLHHGADVHAKDK 715
EA K + + ++ L + + C + TP+ AA R+ + LL HG + ++
Sbjct: 43 EAIKVNNTDILRYLLTVPGLECNAVNASQKTPVMEAASRGRIECLTMLLDHGCNTEGENI 222
Query: 716 GGLVPLHN---ACSYGHYEV------AELLVRHGASVNVADLWKFTPLHEAAAKGKYE 764
G +H+ +C G E+ +L+ + G ++N D + +PLH A + +E
Sbjct: 223 RGKTAMHHCLLSCG-GFVEIEDMVTCMDLVYKAGGNINAQDWFGTSPLHLAISTENFE 393
Score = 40.8 bits (94), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 28/84 (33%), Positives = 43/84 (51%), Gaps = 4/84 (4%)
Frame = +1
Query: 861 ADVNAQDKGGLIPLHNAASYGHVDIAALLIKY----NTCVNATDKWAFTPLHEAAQKGRT 916
AD+N++ KG +H A + DI L+ VNA+ K TP+ EAA +GR
Sbjct: 1 ADINSKFKGSS-AVHEAIKVNNTDILRYLLTVPGLECNAVNASQK---TPVMEAASRGRI 168
Query: 917 QLCALLLAHGADPTMKNQEGQTPL 940
+ +LL HG + +N G+T +
Sbjct: 169 ECLTMLLDHGCNTEGENIRGKTAM 240
Score = 40.0 bits (92), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 40/148 (27%), Positives = 62/148 (41%), Gaps = 4/148 (2%)
Frame = +1
Query: 708 ADVHAKDKGGLVPLHNACSYGHYEVAE-LLVRHGASVNVADLWKFTPLHEAAAKGKYEIC 766
AD+++K KG +H A + ++ LL G N + + TP+ EAA++G+ E
Sbjct: 1 ADINSKFKGS-SAVHEAIKVNNTDILRYLLTVPGLECNAVNASQKTPVMEAASRGRIECL 177
Query: 767 KLLLKHGADPTKKNRDGNTPLD---LVKEGDTDIQXXXXXXXXXXXXXXXXXXXRVQKLC 823
+LL HG + +N G T + L G +I+
Sbjct: 178 TMLLDHGCNTEGENIRGKTAMHHCLLSCGGFVEIEDMVTCMDLVYKAGG----------- 324
Query: 824 TPENINCRDTQGRNSTPLHLAAGYNNLE 851
NIN +D G ++PLHLA N E
Sbjct: 325 ---NINAQDWFG--TSPLHLAISTENFE 393
Score = 38.5 bits (88), Expect = 0.018, Method: Compositional matrix adjust.
Identities = 34/125 (27%), Positives = 55/125 (44%), Gaps = 1/125 (0%)
Frame = +1
Query: 253 LHNACSFGHAEVVSLLL-CQGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGADPNIR 311
+H A + +++ LL G + NA + TP+ EAA +G+I+ +LL HG +
Sbjct: 37 VHEAIKVNNTDILRYLLTVPGLECNAVNASQKTPVMEAASRGRIECLTMLLDHGCNTEGE 216
Query: 312 NTDGKSALDLADPSAKAVLTGEYKKDELLEAARSGNEEKLMALLTPLNVNCHASDGRKST 371
N GK+A+ S + E + M L+ N +A D ++
Sbjct: 217 NIRGKTAMHHCLLSCGGFVEIE-------------DMVTCMDLVYKAGGNINAQDWFGTS 357
Query: 372 PLHLA 376
PLHLA
Sbjct: 358 PLHLA 372
Score = 33.9 bits (76), Expect = 0.48, Method: Compositional matrix adjust.
Identities = 26/100 (26%), Positives = 43/100 (43%), Gaps = 8/100 (8%)
Frame = +1
Query: 819 VQKLCTPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNA- 877
++ L T + C TP+ AA +E LL+HG + ++ G +H+
Sbjct: 73 LRYLLTVPGLECNAVNASQKTPVMEAASRGRIECLTMLLDHGCNTEGENIRGKTAMHHCL 252
Query: 878 -ASYGHVDI------AALLIKYNTCVNATDKWAFTPLHEA 910
+ G V+I L+ K +NA D + +PLH A
Sbjct: 253 LSCGGFVEIEDMVTCMDLVYKAGGNINAQDWFGTSPLHLA 372
Score = 30.4 bits (67), Expect = 5.3, Method: Compositional matrix adjust.
Identities = 18/59 (30%), Positives = 26/59 (44%)
Frame = +1
Query: 543 LLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTALHRAALA 601
LL G N N TP+ AA R + + +L HG + G+TA+H L+
Sbjct: 82 LLTVPGLECNAVNASQKTPVMEAASRGRIECLTMLLDHGCNTEGENIRGKTAMHHCLLS 258
>27108
Length = 449
Score = 51.2 bits (121), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 40/142 (28%), Positives = 69/142 (48%), Gaps = 23/142 (16%)
Frame = -3
Query: 671 SSQNVNCRDLEGRHSTPLHFAAGYNRVSVVEYLLH-HGADVHAKDKGGLVPLHNACSYGH 729
++ VN ++ +G T L AA N +S++++LL G D++++D G LH AC++GH
Sbjct: 420 TADKVNKKNHKGE--TMLIRAAIKNNLSLLKHLLTVPGVDINSQDYAGWTALHEACNHGH 247
Query: 730 YEVAELLVRHGASVNVADLWK--------------------FTPLHEAAAKGKYEICKLL 769
E A L++ S + ++ T LH+A + + KLL
Sbjct: 246 LECARALLKFVPSATLDSFFQSGKNRGKVRKVDMHLANQEGITALHDAVSMNHVSVVKLL 67
Query: 770 LKHGADPTKKNR--DGNTPLDL 789
LK+G K++ G+T +DL
Sbjct: 66 LKYGGSSLLKDKTVSGDTVMDL 1
Score = 50.1 bits (118), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 39/142 (27%), Positives = 66/142 (46%), Gaps = 23/142 (16%)
Frame = -3
Query: 824 TPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLE-HGADVNAQDKGGLIPLHNAASYGH 882
T + +N ++ +G T L AA NNL + ++LL G D+N+QD G LH A ++GH
Sbjct: 420 TADKVNKKNHKGE--TMLIRAAIKNNLSLLKHLLTVPGVDINSQDYAGWTALHEACNHGH 247
Query: 883 VDIAALLIKY--------------------NTCVNATDKWAFTPLHEAAQKGRTQLCALL 922
++ A L+K+ ++ ++ T LH+A + LL
Sbjct: 246 LECARALLKFVPSATLDSFFQSGKNRGKVRKVDMHLANQEGITALHDAVSMNHVSVVKLL 67
Query: 923 LAHGADPTMKNQ--EGQTPLDL 942
L +G +K++ G T +DL
Sbjct: 66 LKYGGSSLLKDKTVSGDTVMDL 1
Score = 45.4 bits (106), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 35/114 (30%), Positives = 48/114 (42%), Gaps = 21/114 (18%)
Frame = -3
Query: 371 TPLHLAAGYNRVRIVQ-LLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGACVN 429
T L AA N + +++ LL G D++++D G LH AC++GH E LLK
Sbjct: 381 TMLIRAAIKNNLSLLKHLLTVPGVDINSQDYAGWTALHEACNHGHLECARALLKFVPSAT 202
Query: 430 AMDLWQ--------------------FTPLHEAASKNRVEVCSLLLSHGADPTL 463
+Q T LH+A S N V V LLL +G L
Sbjct: 201 LDSFFQSGKNRGKVRKVDMHLANQEGITALHDAVSMNHVSVVKLLLKYGGSSLL 40
Score = 35.4 bits (80), Expect = 0.18, Method: Compositional matrix adjust.
Identities = 45/166 (27%), Positives = 65/166 (39%), Gaps = 1/166 (0%)
Frame = -3
Query: 551 VNEKNKDFMTPLHVAAERAHNDVME-VLHKHGAKMNALDTLGQTALHRAALAGHLQTCRL 609
VN+KN T L AA + + +++ +L G +N+ D G TALH A GHL+ R
Sbjct: 408 VNKKNHKGETMLIRAAIKNNLSLLKHLLTVPGVDINSQDYAGWTALHEACNHGHLECARA 229
Query: 610 LLSYGSDPSIISLQGFTAAQMGNEAVQQILSESTPIRTSDVDYRLLEASKAGDLETVKQL 669
LL + + ++ +D G + V
Sbjct: 228 LLKF-------------------------------VPSATLDSFFQSGKNRGKVRKVDMH 142
Query: 670 CSSQNVNCRDLEGRHSTPLHFAAGYNRVSVVEYLLHHGADVHAKDK 715
++Q EG T LH A N VSVV+ LL +G KDK
Sbjct: 141 LANQ-------EG--ITALHDAVSMNHVSVVKLLLKYGGSSLLKDK 31
Score = 34.7 bits (78), Expect = 0.27, Method: Compositional matrix adjust.
Identities = 35/141 (24%), Positives = 60/141 (42%), Gaps = 23/141 (16%)
Frame = -3
Query: 204 AANVNAKDMAGRKSSPLHFAAGFGRKDVVEHLLQM-GANVHARDDGGLIPLHNACSFGHA 262
A VN K+ G + L AA +++HLL + G +++++D G LH AC+ GH
Sbjct: 417 ADKVNKKNHKGE--TMLIRAAIKNNLSLLKHLLTVPGVDINSQDYAGWTALHEACNHGHL 244
Query: 263 EVVSLLL--------------------CQGADPNARDNWNYTPLHEAAIKGKIDVCIVLL 302
E LL + D + + T LH+A + V +LL
Sbjct: 243 ECARALLKFVPSATLDSFFQSGKNRGKVRKVDMHLANQEGITALHDAVSMNHVSVVKLLL 64
Query: 303 QHGADPNIRN--TDGKSALDL 321
++G +++ G + +DL
Sbjct: 63 KYGGSSLLKDKTVSGDTVMDL 1
Score = 34.7 bits (78), Expect = 0.29, Method: Compositional matrix adjust.
Identities = 34/134 (25%), Positives = 53/134 (39%)
Frame = -3
Query: 267 LLLCQGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGADPNIRNTDGKSALDLADPSA 326
LL G D N++D +T LHEA G ++ LL+ PSA
Sbjct: 330 LLTVPGVDINSQDYAGWTALHEACNHGHLECARALLKFV------------------PSA 205
Query: 327 KAVLTGEYKKDELLEAARSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQ 386
D ++ ++ + + V+ H ++ T LH A N V +V+
Sbjct: 204 TL--------DSFFQSGKNRGKVR--------KVDMHLANQEGITALHDAVSMNHVSVVK 73
Query: 387 LLLQHGADVHAKDK 400
LLL++G KDK
Sbjct: 72 LLLKYGGSSLLKDK 31
>33144
Length = 272
Score = 50.8 bits (120), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 31/73 (42%), Positives = 40/73 (54%), Gaps = 1/73 (1%)
Frame = +3
Query: 720 PLHNACSYGHYEVAELLVRHG-ASVNVADLWKFTPLHEAAAKGKYEICKLLLKHGADPTK 778
PLH A G +A +LV+ G +VNV D K TPLH A + I LLL A+P
Sbjct: 21 PLHLAAMNGRTAIAGVLVKKGEVAVNVVDKHKRTPLHYAVQTCELTIIDLLLGRDANPNI 200
Query: 779 KNRDGNTPLDLVK 791
++ DGNTP L +
Sbjct: 201 QDVDGNTPTHLAQ 239
Score = 50.1 bits (118), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 30/72 (41%), Positives = 38/72 (52%), Gaps = 1/72 (1%)
Frame = +3
Query: 873 PLHNAASYGHVDIAALLIKYN-TCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTM 931
PLH AA G IA +L+K VN DK TPLH A Q + LLL A+P +
Sbjct: 21 PLHLAAMNGRTAIAGVLVKKGEVAVNVVDKHKRTPLHYAVQTCELTIIDLLLGRDANPNI 200
Query: 932 KNQEGQTPLDLA 943
++ +G TP LA
Sbjct: 201 QDVDGNTPTHLA 236
Score = 39.7 bits (91), Expect = 0.009, Method: Compositional matrix adjust.
Identities = 24/77 (31%), Positives = 37/77 (48%), Gaps = 1/77 (1%)
Frame = +3
Query: 405 PLHNACSYGHYEVTELLLKHG-ACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTL 463
PLH A G + +L+K G VN +D + TPLH A + + LLL A+P +
Sbjct: 21 PLHLAAMNGRTAIAGVLVKKGEVAVNVVDKHKRTPLHYAVQTCELTIIDLLLGRDANPNI 200
Query: 464 VNCHGKSAVDMAPTPEL 480
+ G + +A +L
Sbjct: 201 QDVDGNTPTHLAQMAKL 251
Score = 38.1 bits (87), Expect = 0.024, Method: Compositional matrix adjust.
Identities = 28/85 (32%), Positives = 41/85 (48%), Gaps = 1/85 (1%)
Frame = +3
Query: 252 PLHNACSFGHAEVVSLLLCQG-ADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGADPNI 310
PLH A G + +L+ +G N D TPLH A ++ + +LL A+PNI
Sbjct: 21 PLHLAAMNGRTAIAGVLVKKGEVAVNVVDKHKRTPLHYAVQTCELTIIDLLLGRDANPNI 200
Query: 311 RNTDGKSALDLADPSAKAVLTGEYK 335
++ DG + LA AK + G K
Sbjct: 201 QDVDGNTPTHLAQ-MAKLPIAGRKK 272
Score = 37.0 bits (84), Expect = 0.057, Method: Compositional matrix adjust.
Identities = 27/72 (37%), Positives = 34/72 (47%), Gaps = 1/72 (1%)
Frame = +3
Query: 372 PLHLAAGYNRVRIVQLLLQHG-ADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGACVNA 430
PLHLAA R I +L++ G V+ DK PLH A + +LLL A N
Sbjct: 21 PLHLAAMNGRTAIAGVLVKKGEVAVNVVDKHKRTPLHYAVQTCELTIIDLLLGRDANPNI 200
Query: 431 MDLWQFTPLHEA 442
D+ TP H A
Sbjct: 201 QDVDGNTPTHLA 236
Score = 35.8 bits (81), Expect = 0.13, Method: Compositional matrix adjust.
Identities = 24/72 (33%), Positives = 34/72 (47%), Gaps = 1/72 (1%)
Frame = +3
Query: 687 PLHFAAGYNRVSVVEYLLHHG-ADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGASVNV 745
PLH AA R ++ L+ G V+ DK PLH A + +LL+ A+ N+
Sbjct: 21 PLHLAAMNGRTAIAGVLVKKGEVAVNVVDKHKRTPLHYAVQTCELTIIDLLLGRDANPNI 200
Query: 746 ADLWKFTPLHEA 757
D+ TP H A
Sbjct: 201 QDVDGNTPTHLA 236
Score = 34.3 bits (77), Expect = 0.34, Method: Compositional matrix adjust.
Identities = 27/75 (36%), Positives = 33/75 (44%), Gaps = 1/75 (1%)
Frame = +3
Query: 837 NSTPLHLAAGYNNLEVAEYLLEHG-ADVNAQDKGGLIPLHNAASYGHVDIAALLIKYNTC 895
N PLHLAA +A L++ G VN DK PLH A + I LL+ +
Sbjct: 12 NWAPLHLAAMNGRTAIAGVLVKKGEVAVNVVDKHKRTPLHYAVQTCELTIIDLLLGRDAN 191
Query: 896 VNATDKWAFTPLHEA 910
N D TP H A
Sbjct: 192 PNIQDVDGNTPTHLA 236
Score = 29.6 bits (65), Expect = 8.3, Method: Compositional matrix adjust.
Identities = 21/66 (31%), Positives = 29/66 (43%)
Frame = +3
Query: 342 AARSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKG 401
AA +G L+ V + D K TPLH A + I+ LLL A+ + +D
Sbjct: 33 AAMNGRTAIAGVLVKKGEVAVNVVDKHKRTPLHYAVQTCELTIIDLLLGRDANPNIQDVD 212
Query: 402 GLVPLH 407
G P H
Sbjct: 213 GNTPTH 230
>22305
Length = 426
Score = 48.5 bits (114), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 22/49 (44%), Positives = 32/49 (65%)
Frame = -3
Query: 262 AEVVSLLLCQGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGADPNI 310
A++ + LL +G N R++W PLHEA ++V VLLQ+GADPN+
Sbjct: 346 ADITTALLERGCSANERNHWGILPLHEALCWENVEVGRVLLQYGADPNV 200
Score = 46.6 bits (109), Expect = 7e-05, Method: Compositional matrix adjust.
Identities = 26/66 (39%), Positives = 36/66 (54%)
Frame = -3
Query: 230 DVVEHLLQMGANVHARDDGGLIPLHNACSFGHAEVVSLLLCQGADPNARDNWNYTPLHEA 289
D+ LL+ G + + R+ G++PLH A + + EV +LL GADPN N PL A
Sbjct: 343 DITTALLERGCSANERNHWGILPLHEALCWENVEVGRVLLQYGADPNVPCETNVVPLTFA 164
Query: 290 AIKGKI 295
A G I
Sbjct: 163 ARTGHI 146
Score = 41.6 bits (96), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 20/48 (41%), Positives = 27/48 (56%)
Frame = -3
Query: 416 EVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTL 463
++T LL+ G N + W PLHEA VEV +LL +GADP +
Sbjct: 343 DITTALLERGCSANERNHWGILPLHEALCWENVEVGRVLLQYGADPNV 200
Score = 40.4 bits (93), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 19/59 (32%), Positives = 28/59 (47%)
Frame = -3
Query: 731 EVAELLVRHGASVNVADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPLDL 789
++ L+ G S N + W PLHEA E+ ++LL++GADP PL
Sbjct: 343 DITTALLERGCSANERNHWGILPLHEALCWENVEVGRVLLQYGADPNVPCETNVVPLTF 167
Score = 40.4 bits (93), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 19/44 (43%), Positives = 27/44 (61%)
Frame = -3
Query: 840 PLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHV 883
PLH A + N+EV LL++GAD N + ++PL AA GH+
Sbjct: 277 PLHEALCWENVEVGRVLLQYGADPNVPCETNVVPLTFAARTGHI 146
Score = 39.7 bits (91), Expect = 0.007, Method: Compositional matrix adjust.
Identities = 20/67 (29%), Positives = 35/67 (52%)
Frame = -3
Query: 848 NNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAALLIKYNTCVNATDKWAFTPL 907
N ++ LLE G N ++ G++PLH A + +V++ +L++Y N + PL
Sbjct: 352 NAADITTALLERGCSANERNHWGILPLHEALCWENVEVGRVLLQYGADPNVPCETNVVPL 173
Query: 908 HEAAQKG 914
AA+ G
Sbjct: 172 TFAARTG 152
Score = 38.9 bits (89), Expect = 0.014, Method: Compositional matrix adjust.
Identities = 19/60 (31%), Positives = 28/60 (46%)
Frame = -3
Query: 884 DIAALLIKYNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTPLDLA 943
DI L++ N + W PLHEA ++ +LL +GADP + + PL A
Sbjct: 343 DITTALLERGCSANERNHWGILPLHEALCWENVEVGRVLLQYGADPNVPCETNVVPLTFA 164
Score = 38.1 bits (87), Expect = 0.022, Method: Compositional matrix adjust.
Identities = 21/67 (31%), Positives = 33/67 (49%)
Frame = -3
Query: 695 NRVSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGASVNVADLWKFTPL 754
N + LL G + ++ G++PLH A + + EV +L+++GA NV PL
Sbjct: 352 NAADITTALLERGCSANERNHWGILPLHEALCWENVEVGRVLLQYGADPNVPCETNVVPL 173
Query: 755 HEAAAKG 761
AA G
Sbjct: 172 TFAARTG 152
Score = 35.4 bits (80), Expect = 0.16, Method: Compositional matrix adjust.
Identities = 21/69 (30%), Positives = 33/69 (47%)
Frame = -3
Query: 380 NRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPL 439
N I LL+ G + ++ G++PLH A + + EV +LL++GA N PL
Sbjct: 352 NAADITTALLERGCSANERNHWGILPLHEALCWENVEVGRVLLQYGADPNVPCETNVVPL 173
Query: 440 HEAASKNRV 448
AA +
Sbjct: 172 TFAARTGHI 146
Score = 35.4 bits (80), Expect = 0.18, Method: Compositional matrix adjust.
Identities = 23/74 (31%), Positives = 35/74 (47%)
Frame = -3
Query: 532 SLHPKRKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDTLG 591
S+ +T LL +G + NE+N + PLH A + +V VL ++GA N
Sbjct: 364 SVRVNAADITTALLERGCSANERNHWGILPLHEALCWENVEVGRVLLQYGADPNVPCETN 185
Query: 592 QTALHRAALAGHLQ 605
L AA GH++
Sbjct: 184 VVPLTFAARTGHIR 143
Score = 33.1 bits (74), Expect = 0.71, Method: Compositional matrix adjust.
Identities = 24/76 (31%), Positives = 33/76 (43%)
Frame = -3
Query: 339 LLEAARSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAK 398
LLE S NE +L PLH A + V + ++LLQ+GAD +
Sbjct: 328 LLERGCSANERNHWGIL----------------PLHEALCWENVEVGRVLLQYGADPNVP 197
Query: 399 DKGGLVPLHNACSYGH 414
+ +VPL A GH
Sbjct: 196 CETNVVPLTFAARTGH 149
Score = 32.3 bits (72), Expect = 1.4, Method: Compositional matrix adjust.
Identities = 15/48 (31%), Positives = 25/48 (52%)
Frame = -3
Query: 572 DVMEVLHKHGAKMNALDTLGQTALHRAALAGHLQTCRLLLSYGSDPSI 619
D+ L + G N + G LH A +++ R+LL YG+DP++
Sbjct: 343 DITTALLERGCSANERNHWGILPLHEALCWENVEVGRVLLQYGADPNV 200
Score = 29.6 bits (65), Expect = 8.8, Method: Compositional matrix adjust.
Identities = 34/105 (32%), Positives = 50/105 (47%), Gaps = 2/105 (1%)
Frame = -3
Query: 642 STPIRTSDVDYRLLEASKAGDLET--VKQLCSSQNVNCRDLEGRHSTPLHFAAGYNRVSV 699
+ P T V R+ A D+ T +++ CS+ N + PLH A + V V
Sbjct: 391 AAPCYTQSVSVRV----NAADITTALLERGCSANERNHWGI-----LPLHEALCWENVEV 239
Query: 700 VEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGASVN 744
LL +GAD + + +VPL A GH +A+LL+ GA VN
Sbjct: 238 GRVLLQYGADPNVPCETNVVPLTFAARTGHIRLAQLLLAAGADVN 104
>30217
Length = 412
Score = 47.8 bits (112), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 28/93 (30%), Positives = 49/93 (52%), Gaps = 3/93 (3%)
Frame = -3
Query: 692 AGYNRVSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVR---HGASVNVADL 748
+G N +++ ++ + ++ G PLH AC G+ +V L+R H +N+ +
Sbjct: 269 SGSNNINI----MNAWEQFYQQNDDGDTPLHLACISGYVDVVAALIRMAPHPCLLNIQND 102
Query: 749 WKFTPLHEAAAKGKYEICKLLLKHGADPTKKNR 781
TPLH AA + I ++LL GA+PT ++R
Sbjct: 101 VAQTPLHLAALTAQPTILRMLLLAGAEPTVRDR 3
Score = 44.3 bits (103), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 25/73 (34%), Positives = 42/73 (57%), Gaps = 3/73 (4%)
Frame = -3
Query: 243 HARDDGGLIPLHNACSFGHAEVVSLLLCQGADP---NARDNWNYTPLHEAAIKGKIDVCI 299
+ ++D G PLH AC G+ +VV+ L+ P N +++ TPLH AA+ + +
Sbjct: 224 YQQNDDGDTPLHLACISGYVDVVAALIRMAPHPCLLNIQNDVAQTPLHLAALTAQPTILR 45
Query: 300 VLLQHGADPNIRN 312
+LL GA+P +R+
Sbjct: 44 MLLLAGAEPTVRD 6
Score = 43.5 bits (101), Expect = 6e-04, Method: Compositional matrix adjust.
Identities = 29/93 (31%), Positives = 48/93 (51%), Gaps = 3/93 (3%)
Frame = -3
Query: 845 AGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAALLIK---YNTCVNATDK 901
+G NN+ + + Q+ G PLH A G+VD+ A LI+ + +N +
Sbjct: 269 SGSNNINI----MNAWEQFYQQNDDGDTPLHLACISGYVDVVAALIRMAPHPCLLNIQND 102
Query: 902 WAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQ 934
A TPLH AA + + +LL GA+PT++++
Sbjct: 101 VAQTPLHLAALTAQPTILRMLLLAGAEPTVRDR 3
Score = 39.3 bits (90), Expect = 0.011, Method: Compositional matrix adjust.
Identities = 22/65 (33%), Positives = 34/65 (52%), Gaps = 3/65 (4%)
Frame = -3
Query: 218 SPLHFAAGFGRKDVVEHLLQMGAN---VHARDDGGLIPLHNACSFGHAEVVSLLLCQGAD 274
+PLH A G DVV L++M + ++ ++D PLH A ++ +LL GA+
Sbjct: 200 TPLHLACISGYVDVVAALIRMAPHPCLLNIQNDVAQTPLHLAALTAQPTILRMLLLAGAE 21
Query: 275 PNARD 279
P RD
Sbjct: 20 PTVRD 6
Score = 38.5 bits (88), Expect = 0.021, Method: Compositional matrix adjust.
Identities = 27/90 (30%), Positives = 44/90 (48%), Gaps = 3/90 (3%)
Frame = -3
Query: 377 AGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLK---HGACVNAMDL 433
+G N + I+ Q + ++ G PLH AC G+ +V L++ H +N +
Sbjct: 269 SGSNNINIMNAWEQ----FYQQNDDGDTPLHLACISGYVDVVAALIRMAPHPCLLNIQND 102
Query: 434 WQFTPLHEAASKNRVEVCSLLLSHGADPTL 463
TPLH AA + + +LL GA+PT+
Sbjct: 101 VAQTPLHLAALTAQPTILRMLLLAGAEPTV 12
>20121
Length = 454
Score = 47.8 bits (112), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 27/87 (31%), Positives = 44/87 (50%), Gaps = 1/87 (1%)
Frame = -1
Query: 687 PLHFAAGYNRVSVVEYLLH-HGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGASVNV 745
P+H+ +N ++ LL D+ KD G LH + S GH E +L+RHGA
Sbjct: 343 PIHWLTWHNNFRELDRLLGLKEHDIETKDPRGRTALHLSVSLGHLESTRVLLRHGAEAGT 164
Query: 746 ADLWKFTPLHEAAAKGKYEICKLLLKH 772
+ ++ LHE G E+ +L+L++
Sbjct: 163 ENNGCWSVLHEGVCSGDPELVQLILQY 83
Score = 43.1 bits (100), Expect = 7e-04, Method: Compositional matrix adjust.
Identities = 29/89 (32%), Positives = 43/89 (48%), Gaps = 3/89 (3%)
Frame = -1
Query: 372 PLHLAAGYNRVRIVQLLL---QHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGACV 428
P+H +N R + LL +H D+ KD G LH + S GH E T +LL+HGA
Sbjct: 343 PIHWLTWHNNFRELDRLLGLKEH--DIETKDPRGRTALHLSVSLGHLESTRVLLRHGAEA 170
Query: 429 NAMDLWQFTPLHEAASKNRVEVCSLLLSH 457
+ ++ LHE E+ L+L +
Sbjct: 169 GTENNGCWSVLHEGVCSGDPELVQLILQY 83
Score = 40.4 bits (93), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 21/66 (31%), Positives = 34/66 (51%)
Frame = -1
Query: 827 NINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIA 886
+I +D +GR T LHL+ +LE LL HGA+ ++ G LH G ++
Sbjct: 274 DIETKDPRGR--TALHLSVSLGHLESTRVLLRHGAEAGTENNGCWSVLHEGVCSGDPELV 101
Query: 887 ALLIKY 892
L+++Y
Sbjct: 100 QLILQY 83
Score = 39.7 bits (91), Expect = 0.009, Method: Compositional matrix adjust.
Identities = 23/87 (26%), Positives = 42/87 (48%), Gaps = 1/87 (1%)
Frame = -1
Query: 219 PLHFAAGFGRKDVVEHLLQMGA-NVHARDDGGLIPLHNACSFGHAEVVSLLLCQGADPNA 277
P+H+ ++ LL + ++ +D G LH + S GH E +LL GA+
Sbjct: 343 PIHWLTWHNNFRELDRLLGLKEHDIETKDPRGRTALHLSVSLGHLESTRVLLRHGAEAGT 164
Query: 278 RDNWNYTPLHEAAIKGKIDVCIVLLQH 304
+N ++ LHE G ++ ++LQ+
Sbjct: 163 ENNGCWSVLHEGVCSGDPELVQLILQY 83
Score = 39.7 bits (91), Expect = 0.009, Method: Compositional matrix adjust.
Identities = 24/89 (26%), Positives = 42/89 (47%), Gaps = 3/89 (3%)
Frame = -1
Query: 840 PLHLAAGYNNLEVAEYLL---EHGADVNAQDKGGLIPLHNAASYGHVDIAALLIKYNTCV 896
P+H +NN + LL EH D+ +D G LH + S GH++ +L+++
Sbjct: 343 PIHWLTWHNNFRELDRLLGLKEH--DIETKDPRGRTALHLSVSLGHLESTRVLLRHGAEA 170
Query: 897 NATDKWAFTPLHEAAQKGRTQLCALLLAH 925
+ ++ LHE G +L L+L +
Sbjct: 169 GTENNGCWSVLHEGVCSGDPELVQLILQY 83
Score = 34.7 bits (78), Expect = 0.24, Method: Compositional matrix adjust.
Identities = 18/64 (28%), Positives = 32/64 (50%)
Frame = -1
Query: 361 NCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTEL 420
+ D R T LHL+ + ++LL+HGA+ ++ G LH G E+ +L
Sbjct: 274 DIETKDPRGRTALHLSVSLGHLESTRVLLRHGAEAGTENNGCWSVLHEGVCSGDPELVQL 95
Query: 421 LLKH 424
+L++
Sbjct: 94 ILQY 83
Score = 33.5 bits (75), Expect = 0.63, Method: Compositional matrix adjust.
Identities = 26/114 (22%), Positives = 49/114 (42%)
Frame = -1
Query: 532 SLHPKRKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDTLG 591
+ H +++ LL K ++ K+ T LH++ H + VL +HGA+ +
Sbjct: 328 TWHNNFRELDRLLGLKEHDIETKDPRGRTALHLSVSLGHLESTRVLLRHGAEAGTENNGC 149
Query: 592 QTALHRAALAGHLQTCRLLLSYGSDPSIISLQGFTAAQMGNEAVQQILSESTPI 645
+ LH +G + +L+L Y Q ++ +G + Q L ES +
Sbjct: 148 WSVLHEGVCSGDPELVQLILQYR------DFQRYSKRTVGIPELLQKLKESQDL 5
>28691
Length = 562
Score = 47.8 bits (112), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 37/113 (32%), Positives = 55/113 (48%), Gaps = 8/113 (7%)
Frame = +1
Query: 866 QDKGGLIPLHNAASYGHVDIAALLIKYNTCVNATDKWAF---TPLHEAAQKGRTQLCAL- 921
+ K GL LH AA HVD +L++ VNA T LHEA G + + ++
Sbjct: 106 ESKSGLPALHLAAKNKHVDCIPVLVQAGADVNAKGPSTIKGNTALHEAVSVGASNVDSVD 285
Query: 922 -LLAHGADPTMKNQEGQTPLDLATA---DDIRALLIDAMPPEALPTCFKPQAT 970
LL+ GAD + N++G+T DLA+ ++I AM L +P+ T
Sbjct: 286 ALLSCGADQNIXNEKGETAYDLASKAGYENIVKRFAAAMGQSQLQKMIRPRNT 444
Score = 45.4 bits (106), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 36/93 (38%), Positives = 48/93 (51%), Gaps = 5/93 (5%)
Frame = +1
Query: 235 LLQMGANVHARDDGGLIPLHNACSFGHAEVVSLLLCQGADPNARDNWNY---TPLHEAAI 291
LL+ A+V ++ GL LH A H + + +L+ GAD NA+ T LHEA
Sbjct: 82 LLRQLASVESK--SGLPALHLAAKNKHVDCIPVLVQAGADVNAKGPSTIKGNTALHEAVS 255
Query: 292 KG--KIDVCIVLLQHGADPNIRNTDGKSALDLA 322
G +D LL GAD NI N G++A DLA
Sbjct: 256 VGASNVDSVDALLSCGADQNIXNEKGETAYDLA 354
Score = 43.9 bits (102), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 36/96 (37%), Positives = 57/96 (59%), Gaps = 5/96 (5%)
Frame = +1
Query: 544 LLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNAL--DTL-GQTALHRAAL 600
LLR+ A+V ++K + LH+AA+ H D + VL + GA +NA T+ G TALH A
Sbjct: 82 LLRQLASV--ESKSGLPALHLAAKNKHVDCIPVLVQAGADVNAKGPSTIKGNTALHEAVS 255
Query: 601 AG--HLQTCRLLLSYGSDPSIISLQGFTAAQMGNEA 634
G ++ + LLS G+D +I + +G TA + ++A
Sbjct: 256 VGASNVDSVDALLSCGADQNIXNEKGETAYDLASKA 363
Score = 41.6 bits (96), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 41/116 (35%), Positives = 55/116 (47%), Gaps = 8/116 (6%)
Frame = +1
Query: 388 LLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGACVNAM---DLWQFTPLHEAAS 444
LL+ A V +K GL LH A H + +L++ GA VNA + T LHEA S
Sbjct: 82 LLRQLASVESK--SGLPALHLAAKNKHVDCIPVLVQAGADVNAKGPSTIKGNTALHEAVS 255
Query: 445 --KNRVEVCSLLLSHGADPTLVNCHGKSAVDMAPTPELRERLTYEFK---GHSLLQ 495
+ V+ LLS GAD + N G++A D+A E + F G S LQ
Sbjct: 256 VGASNVDSVDALLSCGADQNIXNEKGETAYDLASKAGY-ENIVKRFAAAMGQSQLQ 420
>15772
Length = 1282
Score = 45.8 bits (107), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 38/134 (28%), Positives = 60/134 (44%), Gaps = 4/134 (2%)
Frame = -3
Query: 654 LLEASKAGDLETVKQLCSS--QNVNCRDLEGRHSTPLHFAAGYNRVSVVEYLLHHGADVH 711
L +A+ GD + ++ S +VN +D + + T LH+A V + LL HGA
Sbjct: 1274 LHDAASTGDYDALEDYVKSGIYDVNLKDPDAGNKTALHWACQKGFVECIRLLLDHGAKGT 1095
Query: 712 AKDKGGLVPLHNACSYGHYEVAELLVRHGA--SVNVADLWKFTPLHEAAAKGKYEICKLL 769
A+ G P H C+ V L H A V++ D + TP A G + + L
Sbjct: 1094 ARTDTGWTPAH--CAAECNRVTALRALHAALVPVDLTDKYGDTPRRIATLYGHRDCARYL 921
Query: 770 LKHGADPTKKNRDG 783
L+ A+ ++ R G
Sbjct: 920 LQAEAEVAERRRKG 879
Score = 45.1 bits (105), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 45/157 (28%), Positives = 63/157 (40%), Gaps = 3/157 (1%)
Frame = -3
Query: 719 VPLHNACSYGHYEVAELLVRHGA-SVNVAD--LWKFTPLHEAAAKGKYEICKLLLKHGAD 775
+ LH+A S G Y+ E V+ G VN+ D T LH A KG E +LLL HGA
Sbjct: 1280 LELHDAASTGDYDALEDYVKSGIYDVNLKDPDAGNKTALHWACQKGFVECIRLLLDHGAK 1101
Query: 776 PTKKNRDGNTPLDLVKEGDTDIQXXXXXXXXXXXXXXXXXXXRVQKLCTPENINCRDTQG 835
T + G TP E + + P ++ T
Sbjct: 1100 GTARTDTGWTPAHCAAECN-----------------RVTALRALHAALVPVDL----TDK 984
Query: 836 RNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLI 872
TP +A Y + + A YLL+ A+V + + GLI
Sbjct: 983 YGDTPRRIATLYGHRDCARYLLQAEAEVAERRRKGLI 873
Score = 43.5 bits (101), Expect = 6e-04, Method: Compositional matrix adjust.
Identities = 33/110 (30%), Positives = 45/110 (40%)
Frame = -3
Query: 827 NINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIA 886
++N +D N T LH A +E LL+HGA A+ G P H AA V
Sbjct: 1208 DVNLKDPDAGNKTALHWACQKGFVECIRLLLDHGAKGTARTDTGWTPAHCAAECNRVTAL 1029
Query: 887 ALLIKYNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEG 936
L V+ TDK+ TP A G LL A+ + ++G
Sbjct: 1028 RALHAALVPVDLTDKYGDTPRRIATLYGHRDCARYLLQAEAEVAERRRKG 879
Score = 41.6 bits (96), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 27/71 (38%), Positives = 34/71 (47%), Gaps = 3/71 (4%)
Frame = -3
Query: 872 IPLHNAASYGHVDIAALLIK---YNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGAD 928
+ LH+AAS G D +K Y+ + D T LH A QKG + LLL HGA
Sbjct: 1280 LELHDAASTGDYDALEDYVKSGIYDVNLKDPDAGNKTALHWACQKGFVECIRLLLDHGAK 1101
Query: 929 PTMKNQEGQTP 939
T + G TP
Sbjct: 1100 GTARTDTGWTP 1068
Score = 41.2 bits (95), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 38/133 (28%), Positives = 52/133 (39%), Gaps = 2/133 (1%)
Frame = -3
Query: 185 ELLEACRNGDVSRVKRLVDAA--NVNAKDMAGRKSSPLHFAAGFGRKDVVEHLLQMGANV 242
EL +A GD ++ V + +VN KD + LH+A G + + LL GA
Sbjct: 1277 ELHDAASTGDYDALEDYVKSGIYDVNLKDPDAGNKTALHWACQKGFVECIRLLLDHGAKG 1098
Query: 243 HARDDGGLIPLHNACSFGHAEVVSLLLCQGADPNARDNWNYTPLHEAAIKGKIDVCIVLL 302
AR D G P H A + L + D + TP A + G D LL
Sbjct: 1097 TARTDTGWTPAHCAAECNRVTALRALHAALVPVDLTDKYGDTPRRIATLYGHRDCARYLL 918
Query: 303 QHGADPNIRNTDG 315
Q A+ R G
Sbjct: 917 QAEAEVAERRRKG 879
Score = 38.5 bits (88), Expect = 0.018, Method: Compositional matrix adjust.
Identities = 31/79 (39%), Positives = 37/79 (46%), Gaps = 3/79 (3%)
Frame = -3
Query: 373 LHLAAGYNRVRIVQLLLQHGA-DVHAKD--KGGLVPLHNACSYGHYEVTELLLKHGACVN 429
LH AA ++ ++ G DV+ KD G LH AC G E LLL HGA
Sbjct: 1274 LHDAASTGDYDALEDYVKSGIYDVNLKDPDAGNKTALHWACQKGFVECIRLLLDHGAKGT 1095
Query: 430 AMDLWQFTPLHEAASKNRV 448
A +TP H AA NRV
Sbjct: 1094 ARTDTGWTPAHCAAECNRV 1038
Score = 38.5 bits (88), Expect = 0.021, Method: Compositional matrix adjust.
Identities = 31/99 (31%), Positives = 40/99 (40%), Gaps = 1/99 (1%)
Frame = -3
Query: 514 INFKQPQS-HETALHCAVASLHPKRKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHND 572
+N K P + ++TALH A + LLL GA + TP H AAE
Sbjct: 1205 VNLKDPDAGNKTALHWAC---QKGFVECIRLLLDHGAKGTARTDTGWTPAHCAAECNRVT 1035
Query: 573 VMEVLHKHGAKMNALDTLGQTALHRAALAGHLQTCRLLL 611
+ LH ++ D G T A L GH R LL
Sbjct: 1034 ALRALHAALVPVDLTDKYGDTPRRIATLYGHRDCARYLL 918
Score = 37.7 bits (86), Expect = 0.030, Method: Compositional matrix adjust.
Identities = 34/105 (32%), Positives = 46/105 (43%), Gaps = 4/105 (3%)
Frame = -3
Query: 338 ELLEAARSGNEEKLMALLTP--LNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADV 395
EL +AA +G+ + L + +VN D T LH A V ++LLL HGA
Sbjct: 1277 ELHDAASTGDYDALEDYVKSGIYDVNLKDPDAGNKTALHWACQKGFVECIRLLLDHGAKG 1098
Query: 396 HAKDKGGLVPLHNACSYGHYEVTELLLKHGAC--VNAMDLWQFTP 438
A+ G P H C+ VT L H A V+ D + TP
Sbjct: 1097 TARTDTGWTPAH--CAAECNRVTALRALHAALVPVDLTDKYGDTP 969
Score = 36.2 bits (82), Expect = 0.081, Method: Compositional matrix adjust.
Identities = 43/160 (26%), Positives = 64/160 (40%), Gaps = 6/160 (3%)
Frame = -3
Query: 251 IPLHNACSFGHAEVVSLLLCQG------ADPNARDNWNYTPLHEAAIKGKIDVCIVLLQH 304
+ LH+A S G + + + G DP+A N T LH A KG ++ +LL H
Sbjct: 1280 LELHDAASTGDYDALEDYVKSGIYDVNLKDPDAG---NKTALHWACQKGFVECIRLLLDH 1110
Query: 305 GADPNIRNTDGKSALDLADPSAKAVLTGEYKKDELLEAARSGNEEKLMALLTPLNVNCHA 364
GA R G + P+ A E R L A L P+++
Sbjct: 1109 GAKGTARTDTGWT------PAHCAA-----------ECNRVTALRALHAALVPVDL---- 993
Query: 365 SDGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLV 404
+D TP +A Y + LLQ A+V + + GL+
Sbjct: 992 TDKYGDTPRRIATLYGHRDCARYLLQAEAEVAERRRKGLI 873
Score = 34.7 bits (78), Expect = 0.27, Method: Compositional matrix adjust.
Identities = 41/166 (24%), Positives = 61/166 (36%), Gaps = 8/166 (4%)
Frame = -3
Query: 562 LHVAAERAHNDVMEVLHKHG---AKMNALDTLGQTALHRAALAGHLQTCRLLLSYGSDPS 618
LH AA D +E K G + D +TALH A G ++ RLLL +G+ +
Sbjct: 1274 LHDAASTGDYDALEDYVKSGIYDVNLKDPDAGNKTALHWACQKGFVECIRLLLDHGAKGT 1095
Query: 619 IISLQGFTAAQMGNE-----AVQQILSESTPIRTSDVDYRLLEASKAGDLETVKQLCSSQ 673
+ G+T A E A++ + + P+ +D K GD
Sbjct: 1094 ARTDTGWTPAHCAAECNRVTALRALHAALVPVDLTD---------KYGD----------- 975
Query: 674 NVNCRDLEGRHSTPLHFAAGYNRVSVVEYLLHHGADVHAKDKGGLV 719
TP A Y YLL A+V + + GL+
Sbjct: 974 ------------TPRRIATLYGHRDCARYLLQAEAEVAERRRKGLI 873
Score = 30.4 bits (67), Expect = 5.1, Method: Compositional matrix adjust.
Identities = 20/53 (37%), Positives = 24/53 (45%)
Frame = -3
Query: 371 TPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLK 423
TP H AA NRV ++ L V DK G P A YGH + LL+
Sbjct: 1073 TPAHCAAECNRVTALRALHAALVPVDLTDKYGDTPRRIATLYGHRDCARYLLQ 915
>11861
Length = 586
Score = 43.1 bits (100), Expect = 7e-04, Method: Compositional matrix adjust.
Identities = 46/176 (26%), Positives = 69/176 (39%), Gaps = 1/176 (0%)
Frame = -1
Query: 754 LHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPLDLVKEGDTDIQXXXXXXXXXXXXXXX 813
LHEAA + +++I L HGAD K + G TPL V D
Sbjct: 475 LHEAAKRHQWDIVDHCLTHGADINKVDEQGFTPLFRVAYKDV-----------------H 347
Query: 814 XXXXRVQKLCTPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIP 873
V++L + T+ + LA +V + L+ + AD+ DK G P
Sbjct: 346 PDWVAVKELLI-RGADASATESSRKPLVKLAVRKKQWDVVKALILNHADIYRPDKMGQTP 170
Query: 874 LHNAASYGHVDIAALLIKYNT-CVNATDKWAFTPLHEAAQKGRTQLCALLLAHGAD 928
L + ++++ I++ A D T LH A Q R L L+ GAD
Sbjct: 169 LSTLITAANMEMIHFAIQHCPGMAGAVDMSGQTILHVACQLQRPDLLQXLIKDGAD 2
Score = 40.8 bits (94), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 31/103 (30%), Positives = 50/103 (48%), Gaps = 3/103 (2%)
Frame = -1
Query: 841 LHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYG-HVDIAAL--LIKYNTCVN 897
LH AA + ++ ++ L HGAD+N D+ G PL A H D A+ L+ +
Sbjct: 475 LHEAAKRHQWDIVDHCLTHGADINKVDEQGFTPLFRVAYKDVHPDWVAVKELLIRGADAS 296
Query: 898 ATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTPL 940
AT+ + A +K + + L+ + AD ++ GQTPL
Sbjct: 295 ATESSRKPLVKLAVRKKQWDVVKALILNHADIYRPDKMGQTPL 167
Score = 38.1 bits (87), Expect = 0.026, Method: Compositional matrix adjust.
Identities = 47/178 (26%), Positives = 69/178 (38%), Gaps = 2/178 (1%)
Frame = -1
Query: 251 IPLHNACSFGHAEVVSLLLCQGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGADPNI 310
I LH A ++V L GAD N D +TPL A K DV
Sbjct: 481 IALHEAAKRHQWDIVDHCLTHGADINKVDEQGFTPLFRVAYK---DV------------- 350
Query: 311 RNTDGKSALDLADPSAKAVLTGEYKKDELLEAARSGNEEKLMALLTPLN-VNCHASDGRK 369
+ D + +L A A T +K + A R + + AL+ LN + + D
Sbjct: 349 -HPDWVAVKELLIRGADASATESSRKPLVKLAVRKKQWDVVKALI--LNHADIYRPDKMG 179
Query: 370 STPLHLAAGYNRVRIVQLLLQHGADVH-AKDKGGLVPLHNACSYGHYEVTELLLKHGA 426
TPL + ++ +QH + A D G LH AC ++ + L+K GA
Sbjct: 178 QTPLSTLITAANMEMIHFAIQHCPGMAGAVDMSGQTILHVACQLQRPDLLQXLIKDGA 5
Score = 35.4 bits (80), Expect = 0.17, Method: Compositional matrix adjust.
Identities = 25/76 (32%), Positives = 36/76 (47%), Gaps = 4/76 (5%)
Frame = -1
Query: 404 VPLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASK----NRVEVCSLLLSHGA 459
+ LH A +++ + L HGA +N +D FTPL A K + V V LL+ GA
Sbjct: 481 IALHEAAKRHQWDIVDHCLTHGADINKVDEQGFTPLFRVAYKDVHPDWVAVKELLIR-GA 305
Query: 460 DPTLVNCHGKSAVDMA 475
D + K V +A
Sbjct: 304 DASATESSRKPLVKLA 257
Score = 33.5 bits (75), Expect = 0.62, Method: Compositional matrix adjust.
Identities = 20/62 (32%), Positives = 29/62 (46%), Gaps = 3/62 (4%)
Frame = -1
Query: 719 VPLHNACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAAAKG---KYEICKLLLKHGAD 775
+ LH A +++ + + HGA +N D FTPL A K + K LL GAD
Sbjct: 481 IALHEAAKRHQWDIVDHCLTHGADINKVDEQGFTPLFRVAYKDVHPDWVAVKELLIRGAD 302
Query: 776 PT 777
+
Sbjct: 301 AS 296
Score = 31.2 bits (69), Expect = 2.6, Method: Compositional matrix adjust.
Identities = 45/179 (25%), Positives = 72/179 (40%), Gaps = 1/179 (0%)
Frame = -1
Query: 439 LHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMAPTPELRERLTYEFKGHSLLQAAR 498
LHEAA +++ ++ L+HGAD V+ G TP R + Y+
Sbjct: 475 LHEAAKRHQWDIVDHCLTHGADINKVDEQGF-------TPLFR--VAYK---------DV 350
Query: 499 EADLAKVKKTLALEIINFKQPQSHETALHCAVASLHPKRKQVTELLLRKGANVNEKNKDF 558
D VK+ L S + + AV K+ V + L+ A++ +K
Sbjct: 349 HPDWVAVKELLIRGADASATESSRKPLVKLAVRK---KQWDVVKALILNHADIYRPDKMG 179
Query: 559 MTPLHVAAERAHNDVMEVLHKHGAKM-NALDTLGQTALHRAALAGHLQTCRLLLSYGSD 616
TPL A+ +++ +H M A+D GQT LH A + L+ G+D
Sbjct: 178 QTPLSTLITAANMEMIHFAIQHCPGMAGAVDMSGQTILHVACQLQRPDLLQXLIKDGAD 2
Score = 30.0 bits (66), Expect = 6.1, Method: Compositional matrix adjust.
Identities = 26/91 (28%), Positives = 42/91 (46%), Gaps = 3/91 (3%)
Frame = -1
Query: 373 LHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNAC---SYGHYEVTELLLKHGACVN 429
LH AA ++ IV L HGAD++ D+ G PL + + + LL GA +
Sbjct: 475 LHEAAKRHQWDIVDHCLTHGADINKVDEQGFTPLFRVAYKDVHPDWVAVKELLIRGADAS 296
Query: 430 AMDLWQFTPLHEAASKNRVEVCSLLLSHGAD 460
A + + + A K + +V L+ + AD
Sbjct: 295 ATESSRKPLVKLAVRKKQWDVVKALILNHAD 203
>05396
Length = 1865
Score = 43.1 bits (100), Expect = 8e-04, Method: Compositional matrix adjust.
Identities = 29/92 (31%), Positives = 42/92 (45%), Gaps = 1/92 (1%)
Frame = +3
Query: 679 DLEGRHSTPLHFAAGYNRVSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLV- 737
+L+ L F+A V+ + G D+ D G LH A + G +V E L+
Sbjct: 1269 ELQANRIVDLLFSAYNGDVTAIRRCALSGMDMSQPDYDGRTALHVASAEGQLQVVEFLLD 1448
Query: 738 RHGASVNVADLWKFTPLHEAAAKGKYEICKLL 769
R S + D W FTPL +A K+E +LL
Sbjct: 1449 RCKCSPFLVDRWGFTPLDDAVRFEKHEAAELL 1544
Score = 38.9 bits (89), Expect = 0.015, Method: Compositional matrix adjust.
Identities = 27/82 (32%), Positives = 36/82 (43%), Gaps = 2/82 (2%)
Frame = +3
Query: 375 LAAGYN-RVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGACVNAM-D 432
L + YN V ++ G D+ D G LH A + G +V E LL C + D
Sbjct: 1299 LFSAYNGDVTAIRRCALSGMDMSQPDYDGRTALHVASAEGQLQVVEFLLDRCKCSPFLVD 1478
Query: 433 LWQFTPLHEAASKNRVEVCSLL 454
W FTPL +A + E LL
Sbjct: 1479 RWGFTPLDDAVRFEKHEAAELL 1544
Score = 35.4 bits (80), Expect = 0.15, Method: Compositional matrix adjust.
Identities = 19/64 (29%), Positives = 31/64 (48%), Gaps = 1/64 (1%)
Frame = +3
Query: 860 GADVNAQDKGGLIPLHNAASYGHVDIAALLIKYNTCV-NATDKWAFTPLHEAAQKGRTQL 918
G D++ D G LH A++ G + + L+ C D+W FTPL +A + + +
Sbjct: 1353 GMDMSQPDYDGRTALHVASAEGQLQVVEFLLDRCKCSPFLVDRWGFTPLDDAVRFEKHEA 1532
Query: 919 CALL 922
LL
Sbjct: 1533 AELL 1544
Score = 32.0 bits (71), Expect = 1.7, Method: Compositional matrix adjust.
Identities = 23/73 (31%), Positives = 32/73 (43%), Gaps = 2/73 (2%)
Frame = +3
Query: 220 LHFAAGFGRKDVVEHLLQMGANVHARDDGGLIPLHNACSFGHAEVVSLLL--CQGADPNA 277
L F+A G + G ++ D G LH A + G +VV LL C+ P
Sbjct: 1296 LLFSAYNGDVTAIRRCALSGMDMSQPDYDGRTALHVASAEGQLQVVEFLLDRCK-CSPFL 1472
Query: 278 RDNWNYTPLHEAA 290
D W +TPL +A
Sbjct: 1473 VDRWGFTPLDDAV 1511
>20884
Length = 712
Score = 33.1 bits (74), Expect(2) = 8e-04, Method: Compositional matrix adjust.
Identities = 24/65 (36%), Positives = 35/65 (53%), Gaps = 1/65 (1%)
Frame = +2
Query: 826 ENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQD-KGGLIPLHNAASYGHVD 884
+++ R+ +G T HLA +L + LLE GA++N QD K G LH AA G++
Sbjct: 524 QDLAIRNYEG--YTCAHLALQTGHLHILPLLLERGANINEQDGKSGRTLLHMAADLGYLQ 697
Query: 885 IAALL 889
LL
Sbjct: 698 ALELL 712
Score = 28.9 bits (63), Expect(2) = 8e-04, Method: Compositional matrix adjust.
Identities = 23/93 (24%), Positives = 48/93 (51%), Gaps = 4/93 (4%)
Frame = +1
Query: 709 DVHAKDKGGLVPLHNACSYGHYEVAELLVRHGAS---VNVADLWKFTPLHEAAAKGKYEI 765
+++++D+ G LH + + +V+ ++ S +N+ ++ TPLH A A + +
Sbjct: 166 ELYSQDEDGDSYLHMSIIHLLPDVSLKVISVAPSPDYINIPNMLHQTPLHLAVATRQMWV 345
Query: 766 CKLLLKHGADPTKKNRDGNTPLDLV-KEGDTDI 797
+ L+ GA + GNT L + +EG T++
Sbjct: 346 VRRLMVAGAAMEAPDYCGNTALHIACREGMTEM 444
Score = 41.2 bits (95), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 22/52 (42%), Positives = 30/52 (57%)
Frame = +1
Query: 371 TPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLL 422
TPLHLA ++ +V+ L+ GA + A D G LH AC G E+ +LLL
Sbjct: 304 TPLHLAVATRQMWVVRRLMVAGAAMEAPDYCGNTALHIACREGMTEMVKLLL 459
Score = 40.4 bits (93), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 29/97 (29%), Positives = 42/97 (43%)
Frame = +1
Query: 516 FKQPQSHETALHCAVASLHPKRKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVME 575
+ Q + ++ LH ++ L P + +N N TPLH+A V+
Sbjct: 172 YSQDEDGDSYLHMSIIHLLPDVSLKVISVAPSPDYINIPNMLHQTPLHLAVATRQMWVVR 351
Query: 576 VLHKHGAKMNALDTLGQTALHRAALAGHLQTCRLLLS 612
L GA M A D G TALH A G + +LLL+
Sbjct: 352 RLMVAGAAMEAPDYCGNTALHIACREGMTEMVKLLLT 462
Score = 40.4 bits (93), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 22/54 (40%), Positives = 29/54 (53%)
Frame = +1
Query: 684 HSTPLHFAAGYNRVSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLV 737
H TPLH A ++ VV L+ GA + A D G LH AC G E+ +LL+
Sbjct: 298 HQTPLHLAVATRQMWVVRRLMVAGAAMEAPDYCGNTALHIACREGMTEMVKLLL 459
Score = 34.3 bits (77), Expect = 0.36, Method: Compositional matrix adjust.
Identities = 19/51 (37%), Positives = 30/51 (58%), Gaps = 1/51 (1%)
Frame = +2
Query: 528 CAVASLHPKRKQVTELLLRKGANVNEKN-KDFMTPLHVAAERAHNDVMEVL 577
CA +L + LLL +GAN+NE++ K T LH+AA+ + +E+L
Sbjct: 560 CAHLALQTGHLHILPLLLERGANINEQDGKSGRTLLHMAADLGYLQALELL 712
Score = 33.5 bits (75), Expect = 0.53, Method: Compositional matrix adjust.
Identities = 22/67 (32%), Positives = 32/67 (47%)
Frame = +1
Query: 824 TPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHV 883
+P+ IN + + TPLHLA + V L+ GA + A D G LH A G
Sbjct: 265 SPDYINIPNM--LHQTPLHLAVATRQMWVVRRLMVAGAAMEAPDYCGNTALHIACREGMT 438
Query: 884 DIAALLI 890
++ LL+
Sbjct: 439 EMVKLLL 459
Score = 30.8 bits (68), Expect = 3.7, Method: Compositional matrix adjust.
Identities = 20/52 (38%), Positives = 29/52 (55%), Gaps = 1/52 (1%)
Frame = +2
Query: 371 TPLHLAAGYNRVRIVQLLLQHGADVHAKD-KGGLVPLHNACSYGHYEVTELL 421
T HLA + I+ LLL+ GA+++ +D K G LH A G+ + ELL
Sbjct: 557 TCAHLALQTGHLHILPLLLERGANINEQDGKSGRTLLHMAADLGYLQALELL 712
>13622
Length = 1144
Score = 42.4 bits (98), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 23/76 (30%), Positives = 38/76 (50%), Gaps = 9/76 (11%)
Frame = +1
Query: 1030 NISQFLKSLGLEHLRDIFETEQITLDVLADMGHEELKEIGINAYGHRHKLI-------KG 1082
++++ LGL DIF+ ++I + E+LKE+GI +G R K++ KG
Sbjct: 517 DLAELFSKLGLGKYIDIFQQQEIDFSTFLTLNEEDLKELGIGTFGARRKMMLVIADLNKG 696
Query: 1083 VERL--LGGQQGTNPY 1096
RL Q +NP+
Sbjct: 697 HLRLQPTQAQAASNPF 744
>13900
Length = 751
Score = 42.0 bits (97), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 41/143 (28%), Positives = 63/143 (44%), Gaps = 12/143 (8%)
Frame = +1
Query: 828 INCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAA 887
+NC+D + S PLHLA N+ A+ LL+ G+D D G+ PL A + + I
Sbjct: 256 LNCQDPRSGQS-PLHLAVRVNDFHKAKKLLKLGSDPLLPDFSGITPLRMAQGHEYNAIVF 432
Query: 888 LL-----IKYNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQE---GQTP 939
+ I N V T L +A + +LL GA+P + + GQ
Sbjct: 433 YMCYVRDINVNVMVRGE-----TTLQQAVRDNYLLGIQVLLRSGANPDLVVRMPSYGQNC 597
Query: 940 LDLAT----ADDIRALLIDAMPP 958
L+LA + +RAL++ P
Sbjct: 598 LELAVMCRYVNAVRALIVHNCKP 666
Score = 36.2 bits (82), Expect = 0.098, Method: Compositional matrix adjust.
Identities = 42/157 (26%), Positives = 67/157 (42%), Gaps = 5/157 (3%)
Frame = +1
Query: 324 PSAKAVLTGEYKKDELLEAARSGNEEKLMALLTPLNVNCHASDGRK-STPLHLAAGYNRV 382
P LTG ++D L G+ L+ V + D R +PLHLA N
Sbjct: 145 PGQVRALTGS-ERDLLRNIDSXGSMVTFRFLIRLPWVRLNCQDPRSGQSPLHLAVRVNDF 321
Query: 383 RIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVT-ELLLKHGACVNAMDLWQFTPLHE 441
+ LL+ G+D D G+ PL A + + + + VN M + T L +
Sbjct: 322 HKAKKLLKLGSDPLLPDFSGITPLRMAQGHEYNAIVFYMCYVRDINVNVMVRGE-TTLQQ 498
Query: 442 AASKNRVEVCSLLLSHGADPTLV---NCHGKSAVDMA 475
A N + +LL GA+P LV +G++ +++A
Sbjct: 499 AVRDNYLLGIQVLLRSGANPDLVVRMPSYGQNCLELA 609
Score = 34.7 bits (78), Expect = 0.25, Method: Compositional matrix adjust.
Identities = 30/104 (28%), Positives = 47/104 (45%), Gaps = 2/104 (1%)
Frame = +1
Query: 675 VNCRDLEGRHSTPLHFAAGYNRVSVVEYLLHHGADVHAKDKGGLVPLHNACSYGH-YEVA 733
+NC+D S PLH A N + LL G+D D G+ PL A GH Y
Sbjct: 256 LNCQDPRSGQS-PLHLAVRVNDFHKAKKLLKLGSDPLLPDFSGITPLRMA--QGHEYNAI 426
Query: 734 ELLVRHGASVNVADLWKFTPLHEAAAKGKYEI-CKLLLKHGADP 776
+ + +NV + + + A + Y + ++LL+ GA+P
Sbjct: 427 VFYMCYVRDINVNVMVRGETTLQQAVRDNYLLGIQVLLRSGANP 558
>22269
Length = 1060
Score = 41.6 bits (96), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 22/51 (43%), Positives = 29/51 (56%)
Frame = +2
Query: 841 LHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAALLIK 891
+ L NN+E A L+ HGAD NA D+ G PL AA+ G D +L+K
Sbjct: 317 ITLGCQKNNVECARILICHGADYNATDENGESPLFMAAAAGLPDSVMMLLK 469
Score = 35.4 bits (80), Expect(2) = 0.014, Method: Compositional matrix adjust.
Identities = 21/64 (32%), Positives = 30/64 (46%)
Frame = +2
Query: 362 CHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELL 421
CH + T L N V ++L+ HGAD +A D+ G PL A + G + +L
Sbjct: 293 CHTWEDNSIT---LGCQKNNVECARILICHGADYNATDENGESPLFMAAAAGLPDSVMML 463
Query: 422 LKHG 425
LK
Sbjct: 464 LKQA 475
Score = 22.3 bits (46), Expect(2) = 0.014, Method: Composition-based stats.
Identities = 12/22 (54%), Positives = 14/22 (63%)
Frame = +3
Query: 454 LLSHGADPTLVNCHGKSAVDMA 475
L+ HGAD L N G SAV +A
Sbjct: 576 LVRHGADIGLHNEDGDSAVMLA 641
Score = 35.8 bits (81), Expect = 0.11, Method: Compositional matrix adjust.
Identities = 22/50 (44%), Positives = 26/50 (52%)
Frame = +1
Query: 260 GHAEVVSLLLCQGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGADPN 309
G +V+ LLL GA+PNA D +N T H AA G LL GA N
Sbjct: 4 GLHKVMGLLLKYGANPNAVDRYNVTAAHLAAHSGSAQCLKTLLIKGAKAN 153
Score = 34.7 bits (78), Expect = 0.29, Method: Compositional matrix adjust.
Identities = 18/49 (36%), Positives = 25/49 (51%)
Frame = +2
Query: 257 CSFGHAEVVSLLLCQGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHG 305
C + E +L+C GAD NA D +PL AA G D ++LL+
Sbjct: 329 CQKNNVECARILICHGADYNATDENGESPLFMAAAAGLPDSVMMLLKQA 475
Score = 32.3 bits (72), Expect = 1.4, Method: Composition-based stats.
Identities = 21/63 (33%), Positives = 30/63 (47%), Gaps = 6/63 (9%)
Frame = +2
Query: 724 ACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAAAKGKYEICKLLLKHG------ADPT 777
C + E A +L+ HGA N D +PL AAA G + +LLK + P+
Sbjct: 326 GCQKNNVECARILICHGADYNATDENGESPLFMAAAAGLPDSVMMLLKQALGFPILSIPS 505
Query: 778 KKN 780
K+N
Sbjct: 506 KEN 514
Score = 30.8 bits (68), Expect = 3.4, Method: Compositional matrix adjust.
Identities = 19/47 (40%), Positives = 25/47 (53%)
Frame = +1
Query: 413 GHYEVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGA 459
G ++V LLLK+GA NA+D + T H AA + LL GA
Sbjct: 4 GLHKVMGLLLKYGANPNAVDRYNVTAAHLAAHSGSAQCLKTLLIKGA 144
>27416
Length = 377
Score = 41.2 bits (95), Expect = 0.003, Method: Composition-based stats.
Identities = 29/99 (29%), Positives = 40/99 (40%)
Frame = +2
Query: 1210 AGIYFAENSSKSNQYVYGIGGGTGCPTHKDRSCYICHRQMLFCRVTLGKSFLQFSTMKMA 1269
AG+YFA +S+ S + G M RV +G+ S+M+ A
Sbjct: 2 AGVYFAADSATSMGFAKG-------------------GHMFQARVLVGQYTQGNSSMRFA 124
Query: 1270 HAPPGHHSVIGRPSVNGLAYAEYVIYRGEQAYPEYLITY 1308
P H I +VI+ QAYPEYLIT+
Sbjct: 125 SQPTKHQQTIRLCCQRHPECLRFVIFHDAQAYPEYLITF 241
>17893
Length = 453
Score = 40.4 bits (93), Expect = 0.005, Method: Composition-based stats.
Identities = 22/53 (41%), Positives = 30/53 (56%)
Frame = -3
Query: 544 LLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTALH 596
LL+ GA++N ++ T LH AA H DV L HG ++ D G+TALH
Sbjct: 163 LLKNGASINIMDRTGQTLLHEAARAWHVDVTRWLLDHGINIDQPDYYGRTALH 5
Score = 38.5 bits (88), Expect = 0.018, Method: Composition-based stats.
Identities = 22/52 (42%), Positives = 31/52 (59%)
Frame = -3
Query: 421 LLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAV 472
LLK+GA +N MD T LHEAA V+V LL HG + + +G++A+
Sbjct: 163 LLKNGASINIMDRTGQTLLHEAARAWHVDVTRWLLDHGINIDQPDYYGRTAL 8
Score = 35.4 bits (80), Expect = 0.14, Method: Composition-based stats.
Identities = 19/52 (36%), Positives = 30/52 (57%)
Frame = -3
Query: 736 LVRHGASVNVADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPL 787
L+++GAS+N+ D T LHEAA ++ + LL HG + + + G T L
Sbjct: 163 LLKNGASINIMDRTGQTLLHEAARAWHVDVTRWLLDHGINIDQPDYYGRTAL 8
Score = 32.7 bits (73), Expect = 1.00, Method: Composition-based stats.
Identities = 22/57 (38%), Positives = 29/57 (50%)
Frame = -3
Query: 263 EVVSLLLCQGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGADPNIRNTDGKSAL 319
+ V LL GA N D T LHEAA +DV LL HG + + + G++AL
Sbjct: 178 DFVDSLLKNGASINIMDRTGQTLLHEAARAWHVDVTRWLLDHGINIDQPDYYGRTAL 8
Score = 30.4 bits (67), Expect = 4.6, Method: Composition-based stats.
Identities = 18/59 (30%), Positives = 28/59 (47%)
Frame = -3
Query: 882 HVDIAALLIKYNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTPL 940
++D L+K +N D+ T LHEAA+ + LL HG + + G+T L
Sbjct: 184 NLDFVDSLLKNGASINIMDRTGQTLLHEAARAWHVDVTRWLLDHGINIDQPDYYGRTAL 8
>33484
Length = 436
Score = 40.0 bits (92), Expect = 0.007, Method: Compositional matrix adjust.
Identities = 33/111 (29%), Positives = 52/111 (46%), Gaps = 9/111 (8%)
Frame = -2
Query: 671 SSQNVNCRDLEGRHSTP-----LHFAAGY---NRVSVVEYLLHHGADVHAKDKGGLVPLH 722
++Q +NC E + TP F + R + L+ V + G L
Sbjct: 339 ATQAINCMRSEQQGQTPGAEGIFVFGSAQALSERDAGTVRKLYESGSVPDTTEEGESLLS 160
Query: 723 NACSYGHYEVAELLVRHGASVNVADL-WKFTPLHEAAAKGKYEICKLLLKH 772
ACS G+YE+A++L+ A+V + TPL EAA+ G +I +LL+ H
Sbjct: 159 LACSAGYYELAQVLLAMNANVEDRGIKGDCTPLMEAASGGFVDIVRLLILH 7
Score = 37.0 bits (84), Expect = 0.048, Method: Compositional matrix adjust.
Identities = 36/109 (33%), Positives = 49/109 (44%), Gaps = 11/109 (10%)
Frame = -2
Query: 360 VNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGA-DVHAKDKGGLVP---------LHNA 409
+NC S+ + TP A G Q L + A V + G VP L A
Sbjct: 327 INCMRSEQQGQTPG--AEGIFVFGSAQALSERDAGTVRKLYESGSVPDTTEEGESLLSLA 154
Query: 410 CSYGHYEVTELLLKHGACVNAMDL-WQFTPLHEAASKNRVEVCSLLLSH 457
CS G+YE+ ++LL A V + TPL EAAS V++ LL+ H
Sbjct: 153 CSAGYYELAQVLLAMNANVEDRGIKGDCTPLMEAASGGFVDIVRLLILH 7
Score = 35.4 bits (80), Expect = 0.14, Method: Compositional matrix adjust.
Identities = 28/73 (38%), Positives = 38/73 (52%), Gaps = 1/73 (1%)
Frame = -2
Query: 819 VQKLCTPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQD-KGGLIPLHNA 877
V+KL ++ +G + L +AGY E+A+ LL A+V + KG PL A
Sbjct: 225 VRKLYESGSVPDTTEEGESLLSLACSAGY--YELAQVLLAMNANVEDRGIKGDCTPLMEA 52
Query: 878 ASYGHVDIAALLI 890
AS G VDI LLI
Sbjct: 51 ASGGFVDIVRLLI 13
Score = 33.9 bits (76), Expect = 0.50, Method: Compositional matrix adjust.
Identities = 20/53 (37%), Positives = 29/53 (54%), Gaps = 1/53 (1%)
Frame = -2
Query: 253 LHNACSFGHAEVVSLLLCQGADPNARD-NWNYTPLHEAAIKGKIDVCIVLLQH 304
L ACS G+ E+ +LL A+ R + TPL EAA G +D+ +L+ H
Sbjct: 165 LSLACSAGYYELAQVLLAMNANVEDRGIKGDCTPLMEAASGGFVDIVRLLILH 7
>18216
Length = 472
Score = 40.0 bits (92), Expect = 0.007, Method: Composition-based stats.
Identities = 20/44 (45%), Positives = 26/44 (59%)
Frame = +2
Query: 581 GAKMNALDTLGQTALHRAALAGHLQTCRLLLSYGSDPSIISLQG 624
G +NA+D G TA AA GHL + LL G+D S+I+ QG
Sbjct: 275 GVHVNAVDPFGWTAAMSAAFEGHLAVVQTLLEAGADLSVINRQG 406
Score = 31.2 bits (69), Expect = 3.1, Method: Composition-based stats.
Identities = 18/51 (35%), Positives = 28/51 (54%)
Frame = +2
Query: 419 ELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGK 469
E +L G VNA+D + +T AA + + V LL GAD +++N G+
Sbjct: 257 EGVLDKGVHVNAVDPFGWTAAMSAAFEGHLAVVQTLLEAGADLSVINRQGR 409
>25464
Length = 440
Score = 39.7 bits (91), Expect = 0.009, Method: Compositional matrix adjust.
Identities = 27/91 (29%), Positives = 43/91 (47%), Gaps = 5/91 (5%)
Frame = -3
Query: 708 ADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGA-SVNVADLWKFTPLHEAAAKGKYEIC 766
A ++ +D G L AC G ++ +++ +N D TP+H AA I
Sbjct: 438 AYLNVRDSMGRTALSYACLNGRQDIVRCILKEDVLDINEPDNDGNTPIHHAAISANPNIV 259
Query: 767 KLL----LKHGADPTKKNRDGNTPLDLVKEG 793
++L K G +P K+N+ G TPL L +G
Sbjct: 258 RMLAEAFYKFGLNPDKRNKLGYTPLLLACKG 166
Score = 38.9 bits (89), Expect = 0.016, Method: Compositional matrix adjust.
Identities = 29/88 (32%), Positives = 43/88 (48%), Gaps = 5/88 (5%)
Frame = -3
Query: 240 ANVHARDDGGLIPLHNACSFGHAEVVSLLLCQGA-DPNARDNWNYTPLHEAAIKGKIDVC 298
A ++ RD G L AC G ++V +L + D N DN TP+H AAI ++
Sbjct: 438 AYLNVRDSMGRTALSYACLNGRQDIVRCILKEDVLDINEPDNDGNTPIHHAAISANPNIV 259
Query: 299 IVL----LQHGADPNIRNTDGKSALDLA 322
+L + G +P+ RN G + L LA
Sbjct: 258 RMLAEAFYKFGLNPDKRNKLGYTPLLLA 175
Score = 38.1 bits (87), Expect = 0.023, Method: Compositional matrix adjust.
Identities = 32/113 (28%), Positives = 51/113 (45%), Gaps = 5/113 (4%)
Frame = -3
Query: 828 INCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAA 887
+N RD+ GR + G ++ V L E D+N D G P+H+AA + +I
Sbjct: 432 LNVRDSMGRTALSYACLNGRQDI-VRCILKEDVLDINEPDNDGNTPIHHAAISANPNIVR 256
Query: 888 LL----IKYNTCVNATDKWAFTPLHEAAQKGR-TQLCALLLAHGADPTMKNQE 935
+L K+ + +K +TPL A + G LL A PT+++ E
Sbjct: 255 MLAEAFYKFGLNPDKRNKLGYTPLLLACKGGNYVSAYTLLTTTKASPTLRDGE 97
Score = 31.6 bits (70), Expect = 2.2, Method: Compositional matrix adjust.
Identities = 22/81 (27%), Positives = 41/81 (50%), Gaps = 5/81 (6%)
Frame = -3
Query: 537 RKQVTELLLRKGA-NVNEKNKDFMTPLHVAAERAHNDVM----EVLHKHGAKMNALDTLG 591
R+ + +L++ ++NE + D TP+H AA A+ +++ E +K G + + LG
Sbjct: 375 RQDIVRCILKEDVLDINEPDNDGNTPIHHAAISANPNIVRMLAEAFYKFGLNPDKRNKLG 196
Query: 592 QTALHRAALAGHLQTCRLLLS 612
T L A G+ + LL+
Sbjct: 195 YTPLLLACKGGNYVSAYTLLT 133
>05693
Length = 671
Score = 39.7 bits (91), Expect = 0.009, Method: Composition-based stats.
Identities = 42/136 (30%), Positives = 63/136 (46%), Gaps = 6/136 (4%)
Frame = -2
Query: 1180 RMLFHGS--PFINAIIHKGFDERHAYIGG---MFGAGIYFAENSSKSNQYVYGIGGGTGC 1234
+ L+HG+ I I + GF+ +Y G FG G+YFA N+S S Y G
Sbjct: 553 KTLWHGTGADAIENINNYGFNR--SYCGKNATAFGQGVYFAVNTSYSTSSTYSPPDAAG- 383
Query: 1235 PTHKDRSCYICHRQMLFCRVTLGKSFLQFSTMKMAHAPPGHHSVIGRPSVNGLAYA-EYV 1293
+R + C+V +G S S +++ A G ++ + N L YV
Sbjct: 382 -----------NRHIYQCKVLVGHSAKGSSQLRVLPARQG--PILYDSAANDLQKPIMYV 242
Query: 1294 IYRGEQAYPEYLITYQ 1309
I+ QAYPEYLIT++
Sbjct: 241 IFNDTQAYPEYLITFK 194
>12662
Length = 771
Score = 39.7 bits (91), Expect = 0.009, Method: Composition-based stats.
Identities = 20/55 (36%), Positives = 33/55 (60%)
Frame = -1
Query: 1031 ISQFLKSLGLEHLRDIFETEQITLDVLADMGHEELKEIGINAYGHRHKLIKGVER 1085
+ FL S GLE F E++ +++L M ELKEIG+ +G R +L++ ++R
Sbjct: 378 LEMFLWSAGLEAYLHKFLQEKVDMELLVKMSDSELKEIGL-PFGPRKRLLEAIQR 217
>04480
Length = 1878
Score = 39.3 bits (90), Expect = 0.010, Method: Compositional matrix adjust.
Identities = 29/86 (33%), Positives = 40/86 (46%), Gaps = 5/86 (5%)
Frame = -3
Query: 1180 RMLFHGSPFIN--AIIHKGFDERHAYI---GGMFGAGIYFAENSSKSNQYVYGIGGGTGC 1234
R+L+HG+ N +I+ +G A G FG G+YFA+ +KS Y Y G
Sbjct: 1648 RLLWHGTSMANIVSILSRGLLVAPANAPRNGNAFGEGVYFADCFTKSRSYCYNAVG---- 1481
Query: 1235 PTHKDRSCYICHRQMLFCRVTLGKSF 1260
SC + ML C+V LG S
Sbjct: 1480 ------SC----KVMLLCQVALGNSL 1433
>05854
Length = 572
Score = 39.3 bits (90), Expect = 0.010, Method: Composition-based stats.
Identities = 14/25 (56%), Positives = 18/25 (72%)
Frame = +2
Query: 1289 YAEYVIYRGEQAYPEYLITYQIMKP 1313
+ E+V+Y+GEQ YPEYLI Y P
Sbjct: 209 FMEFVVYKGEQVYPEYLIEYMCNSP 283
>36879
Length = 583
Score = 39.3 bits (90), Expect = 0.011, Method: Composition-based stats.
Identities = 24/61 (39%), Positives = 31/61 (50%)
Frame = -3
Query: 425 GACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMAPTPELRERL 484
G ++A+D TPL AA + VC LL GADP + G SA A EL +R+
Sbjct: 494 GINIHAIDDVGETPLMLAAKNGQDYVCERLLEAGADPLAIXLQGNSAFXHALELELEQRV 315
Query: 485 T 485
T
Sbjct: 314 T 312
Score = 38.1 bits (87), Expect = 0.021, Method: Composition-based stats.
Identities = 20/47 (42%), Positives = 27/47 (57%)
Frame = -3
Query: 581 GAKMNALDTLGQTALHRAALAGHLQTCRLLLSYGSDPSIISLQGFTA 627
G ++A+D +G+T L AA G C LL G+DP I LQG +A
Sbjct: 494 GINIHAIDDVGETPLMLAAKNGQDYVCERLLEAGADPLAIXLQGNSA 354
Score = 36.6 bits (83), Expect = 0.069, Method: Composition-based stats.
Identities = 26/60 (43%), Positives = 32/60 (53%), Gaps = 2/60 (3%)
Frame = -3
Query: 265 VSLLL--CQGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGADPNIRNTDGKSALDLA 322
V LLL C+G + +A D+ TPL AA G+ VC LL+ GADP G SA A
Sbjct: 521 VDLLLMDCEGINIHAIDDVGETPLMLAAKNGQDYVCERLLEAGADPLAIXLQGNSAFXHA 342
Score = 34.7 bits (78), Expect = 0.26, Method: Composition-based stats.
Identities = 25/75 (33%), Positives = 37/75 (49%), Gaps = 3/75 (4%)
Frame = -3
Query: 239 GANVHARDDGGLIPLHNACSFGHAEVVSLLLCQGADPNA---RDNWNYTPLHEAAIKGKI 295
G N+HA DD G PL A G V LL GADP A + N + E ++ ++
Sbjct: 494 GINIHAIDDVGETPLMLAAKNGQDYVCERLLEAGADPLAIXLQGNSAFXHALELELEQRV 315
Query: 296 DVCIVLLQHGADPNI 310
V I+ L+ G + ++
Sbjct: 314 TVFIISLKTGLNHDL 270
Score = 31.6 bits (70), Expect = 2.3, Method: Composition-based stats.
Identities = 16/43 (37%), Positives = 23/43 (53%)
Frame = -3
Query: 896 VNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQT 938
++A D TPL AA+ G+ +C LL GADP +G +
Sbjct: 485 IHAIDDVGETPLMLAAKNGQDYVCERLLEAGADPLAIXLQGNS 357
Score = 31.6 bits (70), Expect = 2.3, Method: Composition-based stats.
Identities = 17/46 (36%), Positives = 25/46 (54%)
Frame = -3
Query: 740 GASVNVADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNT 785
G +++ D TPL AA G+ +C+ LL+ GADP GN+
Sbjct: 494 GINIHAIDDVGETPLMLAAKNGQDYVCERLLEAGADPLAIXLQGNS 357
>07234
Length = 543
Score = 38.5 bits (88), Expect = 0.017, Method: Compositional matrix adjust.
Identities = 37/111 (33%), Positives = 46/111 (41%), Gaps = 7/111 (6%)
Frame = -2
Query: 1180 RMLFHGSPFIN--AIIHKGF---DERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGC 1234
++L+HGS N I+ +G G MFG GIYFA+ SKS Y C
Sbjct: 299 QLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANY---------C 147
Query: 1235 PTHKDRSCYICHRQMLFCRVTLGKSFLQFSTMKMAHAPPGHHSV--IGRPS 1283
T K I +L C V LG S + P G HS IGR +
Sbjct: 146 RTSKADPIGI----LLLCEVALGNMHELTSASYVTKLPKGKHSTKGIGRTT 6
>21751
Length = 643
Score = 38.5 bits (88), Expect = 0.020, Method: Composition-based stats.
Identities = 22/62 (35%), Positives = 33/62 (53%), Gaps = 1/62 (1%)
Frame = +3
Query: 837 NSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGL-IPLHNAASYGHVDIAALLIKYNTC 895
+ +PLH+A N+ + LLEHG DVN L P+H A +D+ LLI++
Sbjct: 78 SQSPLHVAILRKNVHLGRLLLEHGEDVNQTFNDSLESPIHQAVRNLDLDMINLLIEFGAD 257
Query: 896 VN 897
+N
Sbjct: 258 LN 263
Score = 37.4 bits (85), Expect = 0.038, Method: Compositional matrix adjust.
Identities = 27/88 (30%), Positives = 41/88 (46%), Gaps = 10/88 (11%)
Frame = +3
Query: 703 LLHHGADVHAKDKGGL--------VPLHNACSYGHYEVAELLVRHGASVN--VADLWKFT 752
L+ +GADVH L PLH A + + LL+ HG VN D + +
Sbjct: 12 LIQYGADVHQLRTVSLDDKVFTSQSPLHVAILRKNVHLGRLLLEHGEDVNQTFNDSLE-S 188
Query: 753 PLHEAAAKGKYEICKLLLKHGADPTKKN 780
P+H+A ++ LL++ GAD + N
Sbjct: 189 PIHQAVRNLDLDMINLLIEFGADLNRPN 272
Score = 37.4 bits (85), Expect = 0.039, Method: Composition-based stats.
Identities = 29/84 (34%), Positives = 43/84 (51%), Gaps = 10/84 (11%)
Frame = +3
Query: 387 LLLQHGADVHAKDKGGL--------VPLHNACSYGHYEVTELLLKHGACVNAM--DLWQF 436
LL+Q+GADVH L PLH A + + LLL+HG VN D +
Sbjct: 9 LLIQYGADVHQLRTVSLDDKVFTSQSPLHVAILRKNVHLGRLLLEHGEDVNQTFNDSLE- 185
Query: 437 TPLHEAASKNRVEVCSLLLSHGAD 460
+P+H+A +++ +LL+ GAD
Sbjct: 186 SPIHQAVRNLDLDMINLLIEFGAD 257
Score = 34.3 bits (77), Expect = 0.31, Method: Composition-based stats.
Identities = 21/60 (35%), Positives = 33/60 (55%), Gaps = 1/60 (1%)
Frame = +3
Query: 371 TPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGL-VPLHNACSYGHYEVTELLLKHGACVN 429
+PLH+A V + +LLL+HG DV+ L P+H A ++ LL++ GA +N
Sbjct: 84 SPLHVAILRKNVHLGRLLLEHGEDVNQTFNDSLESPIHQAVRNLDLDMINLLIEFGADLN 263
Score = 33.9 bits (76), Expect = 0.43, Method: Compositional matrix adjust.
Identities = 28/84 (33%), Positives = 42/84 (50%), Gaps = 9/84 (10%)
Frame = +3
Query: 235 LLQMGANVH-----ARDDGGLI---PLHNACSFGHAEVVSLLLCQGADPNARDNWNY-TP 285
L+Q GA+VH + DD PLH A + + LLL G D N N + +P
Sbjct: 12 LIQYGADVHQLRTVSLDDKVFTSQSPLHVAILRKNVHLGRLLLEHGEDVNQTFNDSLESP 191
Query: 286 LHEAAIKGKIDVCIVLLQHGADPN 309
+H+A +D+ +L++ GAD N
Sbjct: 192 IHQAVRNLDLDMINLLIEFGADLN 263
Score = 32.0 bits (71), Expect = 1.7, Method: Composition-based stats.
Identities = 26/86 (30%), Positives = 47/86 (54%), Gaps = 10/86 (11%)
Frame = +3
Query: 541 TELLLRKGANVNE------KNKDF--MTPLHVAAERAHNDVMEVLHKHGAKMNAL--DTL 590
+ LL++ GA+V++ +K F +PLHVA R + + +L +HG +N D+L
Sbjct: 3 SNLLIQYGADVHQLRTVSLDDKVFTSQSPLHVAILRKNVHLGRLLLEHGEDVNQTFNDSL 182
Query: 591 GQTALHRAALAGHLQTCRLLLSYGSD 616
++ +H+A L LL+ +G+D
Sbjct: 183 -ESPIHQAVRNLDLDMINLLIEFGAD 257
Score = 31.6 bits (70), Expect = 2.4, Method: Compositional matrix adjust.
Identities = 25/90 (27%), Positives = 42/90 (46%), Gaps = 9/90 (10%)
Frame = +3
Query: 853 AEYLLEHGADVNAQDKGGL--------IPLHNAASYGHVDIAALLIKYNTCVNATDKWAF 904
+ L+++GADV+ L PLH A +V + LL+++ VN T +
Sbjct: 3 SNLLIQYGADVHQLRTVSLDDKVFTSQSPLHVAILRKNVHLGRLLLEHGEDVNQTFNDSL 182
Query: 905 -TPLHEAAQKGRTQLCALLLAHGADPTMKN 933
+P+H+A + + LL+ GAD N
Sbjct: 183 ESPIHQAVRNLDLDMINLLIEFGADLNRPN 272
Score = 31.2 bits (69), Expect = 3.2, Method: Composition-based stats.
Identities = 20/60 (33%), Positives = 28/60 (46%), Gaps = 1/60 (1%)
Frame = +3
Query: 686 TPLHFAAGYNRVSVVEYLLHHGADVHAKDKGGL-VPLHNACSYGHYEVAELLVRHGASVN 744
+PLH A V + LL HG DV+ L P+H A ++ LL+ GA +N
Sbjct: 84 SPLHVAILRKNVHLGRLLLEHGEDVNQTFNDSLESPIHQAVRNLDLDMINLLIEFGADLN 263
>02069
Length = 1721
Score = 37.7 bits (86), Expect = 0.030, Method: Compositional matrix adjust.
Identities = 25/89 (28%), Positives = 41/89 (46%), Gaps = 2/89 (2%)
Frame = +3
Query: 1149 RIQKVVNKKLRERFCHRQKEVSXXXXXXXXXRMLFHGSPF--INAIIHKGFDERHAYIGG 1206
RI ++ N L R+ +++++ MLFHG+ +N+I +GF+ G
Sbjct: 33 RIFRIENPALWARYYWKREKMKKTNEGHIKETMLFHGTSHENVNSICRRGFE------CG 194
Query: 1207 MFGAGIYFAENSSKSNQYVYGIGGGTGCP 1235
GIYF+ +S S+ Y I CP
Sbjct: 195 QRTRGIYFSPDSRMSHAYTTCISNRC-CP 278
>09214
Length = 2116
Score = 37.4 bits (85), Expect = 0.046, Method: Compositional matrix adjust.
Identities = 22/56 (39%), Positives = 32/56 (57%), Gaps = 3/56 (5%)
Frame = -3
Query: 667 KQLCSSQNVNCR---DLEGRHSTPLHFAAGYNRVSVVEYLLHHGADVHAKDKGGLV 719
K+L +NV+ + GR T LH+ A + +VV+YLL HGAD +A D G +
Sbjct: 1664 KKLVEVKNVDVNAQNKMNGR--TALHWGAKRDHQTVVQYLLSHGADKNAVDNDGKI 1503
Score = 35.0 bits (79), Expect = 0.18, Method: Compositional matrix adjust.
Identities = 21/54 (38%), Positives = 28/54 (51%), Gaps = 1/54 (1%)
Frame = -3
Query: 820 QKLCTPENINCRDTQGRNS-TPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLI 872
+KL +N++ N T LH A ++ V +YLL HGAD NA D G I
Sbjct: 1664 KKLVEVKNVDVNAQNKMNGRTALHWGAKRDHQTVVQYLLSHGADKNAVDNDGKI 1503
Score = 33.1 bits (74), Expect = 0.69, Method: Compositional matrix adjust.
Identities = 21/61 (34%), Positives = 30/61 (49%), Gaps = 1/61 (1%)
Frame = -3
Query: 893 NTCVNATDKW-AFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTPLDLATADDIRAL 951
N VNA +K T LH A++ + LL+HGAD + +G+ L T D+ L
Sbjct: 1643 NVDVNAQNKMNGRTALHWGAKRDHQTVVQYLLSHGADKNAVDNDGKIAGQLTTNSDVHTL 1464
Query: 952 L 952
L
Sbjct: 1463 L 1461
Score = 33.1 bits (74), Expect = 0.78, Method: Compositional matrix adjust.
Identities = 27/79 (34%), Positives = 35/79 (44%), Gaps = 2/79 (2%)
Frame = -3
Query: 256 ACSFG-HAEVVSLLLCQGADPNARDNWN-YTPLHEAAIKGKIDVCIVLLQHGADPNIRNT 313
+C + H L+ + D NA++ N T LH A + V LL HGAD N +
Sbjct: 1694 SCQYW*HGVAKKLVEVKNVDVNAQNKMNGRTALHWGAKRDHQTVVQYLLSHGADKNAVDN 1515
Query: 314 DGKSALDLADPSAKAVLTG 332
DGK A L S L G
Sbjct: 1514 DGKIAGQLTTNSDVHTLLG 1458
Score = 30.4 bits (67), Expect = 5.0, Method: Compositional matrix adjust.
Identities = 22/61 (36%), Positives = 30/61 (49%), Gaps = 1/61 (1%)
Frame = -3
Query: 583 KMNALDTLGQTALHRAALAGHLQTCRLLLSYGSDPSIISLQGFTAAQM-GNEAVQQILSE 641
KMN G+TALH A H + LLS+G+D + + G A Q+ N V +L
Sbjct: 1619 KMN-----GRTALHWGAKRDHQTVVQYLLSHGADKNAVDNDGKIAGQLTTNSDVHTLLGG 1455
Query: 642 S 642
S
Sbjct: 1454 S 1452
Score = 30.0 bits (66), Expect = 7.4, Method: Compositional matrix adjust.
Identities = 16/35 (45%), Positives = 19/35 (54%)
Frame = -3
Query: 437 TPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSA 471
T LH A ++ V LLSHGAD V+ GK A
Sbjct: 1604 TALHWGAKRDHQTVVQYLLSHGADKNAVDNDGKIA 1500
>30463
Length = 412
Score = 37.0 bits (84), Expect = 0.049, Method: Compositional matrix adjust.
Identities = 28/77 (36%), Positives = 35/77 (45%)
Frame = -1
Query: 221 HFAAGFGRKDVVEHLLQMGANVHARDDGGLIPLHNACSFGHAEVVSLLLCQGADPNARDN 280
H AA G + V L MGA++ R PLH A S GH E V L+ A A D
Sbjct: 373 HLAAMNGHSNAVMVLNIMGASIDCRTVDKQTPLHLASSAGHIECVKCLVANKASLTAEDA 194
Query: 281 WNYTPLHEAAIKGKIDV 297
++ T A G+ DV
Sbjct: 193 FSRTAYDLADQYGQNDV 143
Score = 36.6 bits (83), Expect = 0.069, Method: Compositional matrix adjust.
Identities = 26/82 (31%), Positives = 38/82 (46%), Gaps = 1/82 (1%)
Frame = -1
Query: 717 GLVPLHNACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAAAKGKYEICKLLLKHGADP 776
G H A GH +L GAS++ + K TPLH A++ G E K L+ + A
Sbjct: 388 GYTATHLAAMNGHSNAVMVLNIMGASIDCRTVDKQTPLHLASSAGHIECVKCLVANKASL 209
Query: 777 TKKNRDGNTPLDLVKE-GDTDI 797
T ++ T DL + G D+
Sbjct: 208 TAEDAFSRTAYDLADQYGQNDV 143
Score = 34.7 bits (78), Expect = 0.24, Method: Compositional matrix adjust.
Identities = 24/81 (29%), Positives = 40/81 (49%), Gaps = 1/81 (1%)
Frame = -1
Query: 342 AARSGNEEKLMAL-LTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDK 400
AA +G+ +M L + +++C D K TPLHLA+ + V+ L+ + A + A+D
Sbjct: 367 AAMNGHSNAVMVLNIMGASIDCRTVD--KQTPLHLASSAGHIECVKCLVANKASLTAEDA 194
Query: 401 GGLVPLHNACSYGHYEVTELL 421
A YG +V + L
Sbjct: 193 FSRTAYDLADQYGQNDVADFL 131
Score = 33.9 bits (76), Expect = 0.49, Method: Compositional matrix adjust.
Identities = 24/75 (32%), Positives = 34/75 (45%)
Frame = -1
Query: 249 GLIPLHNACSFGHAEVVSLLLCQGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGADP 308
G H A GH+ V +L GA + R TPLH A+ G I+ L+ + A
Sbjct: 388 GYTATHLAAMNGHSNAVMVLNIMGASIDCRTVDKQTPLHLASSAGHIECVKCLVANKASL 209
Query: 309 NIRNTDGKSALDLAD 323
+ ++A DLAD
Sbjct: 208 TAEDAFSRTAYDLAD 164
Score = 33.5 bits (75), Expect = 0.66, Method: Compositional matrix adjust.
Identities = 25/84 (29%), Positives = 35/84 (41%)
Frame = -1
Query: 686 TPLHFAAGYNRVSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGASVNV 745
T H AA + V L GA + + PLH A S GH E + LV + AS+
Sbjct: 382 TATHLAAMNGHSNAVMVLNIMGASIDCRTVDKQTPLHLASSAGHIECVKCLVANKASLTA 203
Query: 746 ADLWKFTPLHEAAAKGKYEICKLL 769
D + T A G+ ++ L
Sbjct: 202 EDAFSRTAYDLADQYGQNDVADFL 131
Score = 33.1 bits (74), Expect = 0.70, Method: Compositional matrix adjust.
Identities = 18/53 (33%), Positives = 31/53 (58%)
Frame = -1
Query: 560 TPLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTALHRAALAGHLQTCRLLLS 612
T H+AA H++ + VL+ GA ++ QT LH A+ AGH++ + L++
Sbjct: 382 TATHLAAMNGHSNAVMVLNIMGASIDCRTVDKQTPLHLASSAGHIECVKCLVA 224
Score = 32.7 bits (73), Expect = 1.0, Method: Compositional matrix adjust.
Identities = 21/71 (29%), Positives = 36/71 (50%)
Frame = -1
Query: 524 TALHCAVASLHPKRKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAK 583
TA H A + H V ++ GA+++ + D TPLH+A+ H + ++ L + A
Sbjct: 382 TATHLAAMNGHSNAVMVLNIM---GASIDCRTVDKQTPLHLASSAGHIECVKCLVANKAS 212
Query: 584 MNALDTLGQTA 594
+ A D +TA
Sbjct: 211 LTAEDAFSRTA 179
Score = 31.6 bits (70), Expect = 2.2, Method: Compositional matrix adjust.
Identities = 24/86 (27%), Positives = 41/86 (47%), Gaps = 2/86 (2%)
Frame = -1
Query: 839 TPLHLAA--GYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAALLIKYNTCV 896
T HLAA G++N + ++ GA ++ + PLH A+S GH++ L+ +
Sbjct: 382 TATHLAAMNGHSNAVMVLNIM--GASIDCRTVDKQTPLHLASSAGHIECVKCLVANKASL 209
Query: 897 NATDKWAFTPLHEAAQKGRTQLCALL 922
A D ++ T A Q G+ + L
Sbjct: 208 TAEDAFSRTAYDLADQYGQNDVADFL 131
Score = 31.2 bits (69), Expect = 3.1, Method: Compositional matrix adjust.
Identities = 25/84 (29%), Positives = 35/84 (41%)
Frame = -1
Query: 371 TPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGACVNA 430
T HLAA V +L GA + + PLH A S GH E + L+ + A + A
Sbjct: 382 TATHLAAMNGHSNAVMVLNIMGASIDCRTVDKQTPLHLASSAGHIECVKCLVANKASLTA 203
Query: 431 MDLWQFTPLHEAASKNRVEVCSLL 454
D + T A + +V L
Sbjct: 202 EDAFSRTAYDLADQYGQNDVADFL 131
>02351
Length = 939
Score = 36.6 bits (83), Expect = 0.072, Method: Composition-based stats.
Identities = 26/60 (43%), Positives = 31/60 (51%)
Frame = +3
Query: 366 DGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHG 425
DGR T LH+AA V VQLLL + A+V D G L A + G E T+LL G
Sbjct: 465 DGR--TALHIAAALGNVVYVQLLLWYCANVKVVDHEGRNALWYARTSGSVECTDLLAAAG 638
>08755
Length = 885
Score = 36.2 bits (82), Expect = 0.084, Method: Compositional matrix adjust.
Identities = 16/47 (34%), Positives = 26/47 (55%)
Frame = +3
Query: 366 DGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSY 412
DG TPL LAA + +Q+L+ G+ + ++ G+ LH+ SY
Sbjct: 741 DGSGVTPLMLAASMTKTAALQILIGAGSSIDCRNNAGMCALHHCFSY 881
Score = 35.0 bits (79), Expect = 0.21, Method: Compositional matrix adjust.
Identities = 24/75 (32%), Positives = 39/75 (52%), Gaps = 1/75 (1%)
Frame = +3
Query: 523 ETALHCAVASLHPKRKQVTELLLRKGANVNEK-NKDFMTPLHVAAERAHNDVMEVLHKHG 581
++ALH AV K +V +LL GAN + K + +TPL +AA +++L G
Sbjct: 657 QSALHIAV-----KNPEVISVLLAHGANPDVKVDGSGVTPLMLAASMTKTAALQILIGAG 821
Query: 582 AKMNALDTLGQTALH 596
+ ++ + G ALH
Sbjct: 822 SSIDCRNNAGMCALH 866
Score = 32.0 bits (71), Expect = 1.9, Method: Compositional matrix adjust.
Identities = 13/48 (27%), Positives = 26/48 (54%)
Frame = +3
Query: 680 LEGRHSTPLHFAAGYNRVSVVEYLLHHGADVHAKDKGGLVPLHNACSY 727
++G TPL AA + + ++ L+ G+ + ++ G+ LH+ SY
Sbjct: 738 VDGSGVTPLMLAASMTKTAALQILIGAGSSIDCRNNAGMCALHHCFSY 881
Score = 30.8 bits (68), Expect = 4.2, Method: Compositional matrix adjust.
Identities = 14/48 (29%), Positives = 23/48 (47%)
Frame = +3
Query: 833 TQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASY 880
G TPL LAA + L+ G+ ++ ++ G+ LH+ SY
Sbjct: 738 VDGSGVTPLMLAASMTKTAALQILIGAGSSIDCRNNAGMCALHHCFSY 881
>35952
Length = 1624
Score = 36.2 bits (82), Expect = 0.10, Method: Compositional matrix adjust.
Identities = 28/77 (36%), Positives = 41/77 (53%), Gaps = 2/77 (2%)
Frame = -1
Query: 861 ADVNAQD-KGGLIPLHNAASYGHVDIAA-LLIKYNTCVNATDKWAFTPLHEAAQKGRTQL 918
A+V+ D K G LH+A + +A LL++ N VNA TPLH A +G +
Sbjct: 1003 ANVDLPDGKSGRTALHHAVELDDLPVAGFLLMEANADVNARCFDGNTPLHVACCRGLIGM 824
Query: 919 CALLLAHGADPTMKNQE 935
ALL+ GA ++N+E
Sbjct: 823 VALLMTAGALTDVENEE 773
Score = 35.4 bits (80), Expect = 0.17, Method: Compositional matrix adjust.
Identities = 29/85 (34%), Positives = 38/85 (44%), Gaps = 6/85 (7%)
Frame = -1
Query: 234 HLLQMGANVHARDD-----GGLIPLHNACSFGHAEVVSLLLCQG-ADPNARDNWNYTPLH 287
H +GA V A D G LH+A V LL + AD NAR TPLH
Sbjct: 1033 HAAYVGAGVRANVDLPDGKSGRTALHHAVELDDLPVAGFLLMEANADVNARCFDGNTPLH 854
Query: 288 EAAIKGKIDVCIVLLQHGADPNIRN 312
A +G I + +L+ GA ++ N
Sbjct: 853 VACCRGLIGMVALLMTAGALTDVEN 779
Score = 33.9 bits (76), Expect = 0.47, Method: Compositional matrix adjust.
Identities = 23/61 (37%), Positives = 31/61 (50%), Gaps = 1/61 (1%)
Frame = -1
Query: 686 TPLHFAAGYNRVSVVEYLLHHG-ADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGASVN 744
T LH A + + V +LL ADV+A+ G PLH AC G + LL+ GA +
Sbjct: 967 TALHHAVELDDLPVAGFLLMEANADVNARCFDGNTPLHVACCRGLIGMVALLMTAGALTD 788
Query: 745 V 745
V
Sbjct: 787 V 785
Score = 32.7 bits (73), Expect = 0.90, Method: Compositional matrix adjust.
Identities = 24/74 (32%), Positives = 36/74 (48%), Gaps = 2/74 (2%)
Frame = -1
Query: 358 LNVNCHASDGRKS-TPLHLAAGYNRVRIVQ-LLLQHGADVHAKDKGGLVPLHNACSYGHY 415
+ N DG+ T LH A + + + LL++ ADV+A+ G PLH AC G
Sbjct: 1009 VRANVDLPDGKSGRTALHHAVELDDLPVAGFLLMEANADVNARCFDGNTPLHVACCRGLI 830
Query: 416 EVTELLLKHGACVN 429
+ LL+ GA +
Sbjct: 829 GMVALLMTAGALTD 788
>06293
Length = 2053
Score = 35.8 bits (81), Expect = 0.11, Method: Compositional matrix adjust.
Identities = 30/81 (37%), Positives = 36/81 (44%), Gaps = 1/81 (1%)
Frame = +1
Query: 1205 GGMFGAGIYFAENSSKSNQYVYGIGGGTGCPTHKDRSCYICHRQMLFCRVTLGKSFLQFS 1264
G MFG G+YFA+ SSKS Y C K ++ ML C V+LG +
Sbjct: 1210 GYMFGKGVYFADMSSKSANY---------CFASKQKNV----GMMLLCDVSLGNINEKLD 1350
Query: 1265 TMKMAHA-PPGHHSVIGRPSV 1284
A P G HSV G SV
Sbjct: 1351 ADYYADKLPSGKHSVKGCGSV 1413
>04513
Length = 434
Score = 35.0 bits (79), Expect = 0.23, Method: Composition-based stats.
Identities = 20/52 (38%), Positives = 30/52 (57%), Gaps = 1/52 (1%)
Frame = -2
Query: 409 ACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEA-ASKNRVEVCSLLLSHGA 459
A YG + ++LL G VNA+ ++ TPL A S++ V V +LL+ H A
Sbjct: 433 ASKYGDKDTVQVLLDKGGQVNAVGKYKLTPLMWACCSRDDVAVVNLLIDHHA 278
>18883
Length = 1122
Score = 34.3 bits (77), Expect = 0.32, Method: Composition-based stats.
Identities = 12/22 (54%), Positives = 17/22 (77%)
Frame = -1
Query: 1289 YAEYVIYRGEQAYPEYLITYQI 1310
+ E+V+Y +QAYPEYLI Y +
Sbjct: 1110 FREFVVYSDDQAYPEYLIEYTL 1045
>36917
Length = 443
Score = 34.3 bits (77), Expect = 0.36, Method: Compositional matrix adjust.
Identities = 17/40 (42%), Positives = 24/40 (60%)
Frame = -1
Query: 838 STPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNA 877
+ LH+AA +EVAE+LL++ V+ QD PLH A
Sbjct: 122 TQQLHIAAANGYIEVAEFLLDNHVSVDRQDHESWQPLHAA 3
>01194
Length = 1142
Score = 33.9 bits (76), Expect = 0.46, Method: Composition-based stats.
Identities = 12/22 (54%), Positives = 17/22 (77%)
Frame = +3
Query: 1289 YAEYVIYRGEQAYPEYLITYQI 1310
+ E+V+Y +QAYPEYLI Y +
Sbjct: 150 FREFVVYSDDQAYPEYLIEYTL 215
>28491
Length = 394
Score = 33.5 bits (75), Expect = 0.55, Method: Compositional matrix adjust.
Identities = 26/69 (37%), Positives = 35/69 (50%), Gaps = 8/69 (11%)
Frame = +3
Query: 831 RDTQGRNS---TPLHLAAGY----NNLEVAEYLLEHGADVNAQDKGGLIPL-HNAASYGH 882
R + RN TPL A+ Y + + + + LL G+DVNAQD G+ L H A G
Sbjct: 171 RSMEIRNEHSCTPLLYASRYAKGDHGIYLIKLLLRQGSDVNAQDDAGMTSLMHVIAEGGS 350
Query: 883 VDIAALLIK 891
VD LI+
Sbjct: 351 VDAVRPLIR 377
Score = 32.0 bits (71), Expect = 1.5, Method: Compositional matrix adjust.
Identities = 23/84 (27%), Positives = 44/84 (52%), Gaps = 4/84 (4%)
Frame = +3
Query: 334 YKKDELLEAARSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNR----VRIVQLLL 389
+++++L A KL ALL+ + + TPL A+ Y + + +++LLL
Sbjct: 96 HEEEKLFTAIAFHKLHKLSALLSEAR-SMEIRNEHSCTPLLYASRYAKGDHGIYLIKLLL 272
Query: 390 QHGADVHAKDKGGLVPLHNACSYG 413
+ G+DV+A+D G+ L + + G
Sbjct: 273 RQGSDVNAQDDAGMTSLMHVIAEG 344
Score = 29.6 bits (65), Expect = 7.5, Method: Compositional matrix adjust.
Identities = 24/82 (29%), Positives = 38/82 (46%), Gaps = 5/82 (6%)
Frame = +3
Query: 220 LHFAAGFGRKDVVEHLLQMGANVHARDDGGLIPLHNACSFGHAE----VVSLLLCQGADP 275
L A F + + LL ++ R++ PL A + + ++ LLL QG+D
Sbjct: 111 LFTAIAFHKLHKLSALLSEARSMEIRNEHSCTPLLYASRYAKGDHGIYLIKLLLRQGSDV 290
Query: 276 NARDNWNYTPL-HEAAIKGKID 296
NA+D+ T L H A G +D
Sbjct: 291 NAQDDAGMTSLMHVIAEGGSVD 356
>28345
Length = 365
Score = 33.5 bits (75), Expect = 0.56, Method: Compositional matrix adjust.
Identities = 26/70 (37%), Positives = 32/70 (45%), Gaps = 2/70 (2%)
Frame = +3
Query: 849 NLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAALLIKYNTC-VNATDKWAFT-P 906
N+EV LL+ G DVN +D G PL A A LLI C +N D + P
Sbjct: 3 NVEVVSLLLDLGCDVNGEDFDGGFPLSLALRKHLSQXALLLISQPACDLNVLDPVSKQRP 182
Query: 907 LHEAAQKGRT 916
L A +G T
Sbjct: 183 LCSAVLEGLT 212
>10413
Length = 578
Score = 32.7 bits (73), Expect = 1.0, Method: Composition-based stats.
Identities = 17/47 (36%), Positives = 29/47 (61%)
Frame = +2
Query: 1034 FLKSLGLEHLRDIFETEQITLDVLADMGHEELKEIGINAYGHRHKLI 1080
L +GL+ D+F+ EQI L+ L+ ++LK++G+ G R KL+
Sbjct: 338 LLGKVGLKDKMDVFQQEQIDLESLSMCSEQDLKDLGL-PMGPRKKLL 475
>34970
Length = 505
Score = 32.7 bits (73), Expect = 1.0, Method: Composition-based stats.
Identities = 13/33 (39%), Positives = 23/33 (69%)
Frame = -1
Query: 1054 LDVLADMGHEELKEIGINAYGHRHKLIKGVERL 1086
+D + D+ E+L+EIGI GH+ K++ V+R+
Sbjct: 445 IDYVTDITWEDLEEIGIKKLGHQKKIMLAVDRM 347
>20955
Length = 1122
Score = 32.3 bits (72), Expect = 1.3, Method: Compositional matrix adjust.
Identities = 34/128 (26%), Positives = 59/128 (46%), Gaps = 14/128 (10%)
Frame = +2
Query: 662 DLETVKQLCSSQNVNCRDLEGRHSTPLHFAA-GYNR---VSVVEYLLHHGADVHAKDKGG 717
+L V+ + + VN D R T LH A +NR +S + +L+HHGAD KD
Sbjct: 8 ELSEVEGVFPAYQVNAVD--DRGFTLLHLATQDWNRDVGLSNIRFLMHHGADPGVKDSNS 181
Query: 718 LVPLHNACSYGHYEV-AELLVRHGASVNVAD-----LWK----FTPLHEAAAKGKYEICK 767
+ + + G + ++LV V VA+ W+ ++ LH A+G + +
Sbjct: 182 MTVIQSLVGKGDTQCDVDMLVE---VVTVAESIPPHCWRPVSGWSALHILVARGLCQHIQ 352
Query: 768 LLLKHGAD 775
++ GA+
Sbjct: 353 PFIEKGAN 376
Score = 31.2 bits (69), Expect = 2.8, Method: Compositional matrix adjust.
Identities = 21/58 (36%), Positives = 29/58 (50%), Gaps = 5/58 (8%)
Frame = +2
Query: 743 VNVADLWKFTPLHEAAAKGKYEI----CKLLLKHGADPTKKNRDGNTPL-DLVKEGDT 795
VN D FT LH A ++ + L+ HGADP K+ + T + LV +GDT
Sbjct: 47 VNAVDDRGFTLLHLATQDWNRDVGLSNIRFLMHHGADPGVKDSNSMTVIQSLVGKGDT 220
>20988
Length = 530
Score = 32.0 bits (71), Expect = 1.9, Method: Composition-based stats.
Identities = 13/27 (48%), Positives = 19/27 (70%)
Frame = -3
Query: 413 GHYEVTELLLKHGACVNAMDLWQFTPL 439
GH+ + ++LL HGA +NA+DL TP
Sbjct: 87 GHWAIVDMLLSHGADLNAVDLLGQTPF 7
Score = 30.8 bits (68), Expect = 3.5, Method: Composition-based stats.
Identities = 17/44 (38%), Positives = 25/44 (56%)
Frame = -3
Query: 550 NVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDTLGQT 593
++NE F T A H ++++L HGA +NA+D LGQT
Sbjct: 132 DMNEDTAAFTT----RAAPGHWAIVDMLLSHGADLNAVDLLGQT 13
Score = 29.6 bits (65), Expect = 8.4, Method: Composition-based stats.
Identities = 11/27 (40%), Positives = 17/27 (62%)
Frame = -3
Query: 728 GHYEVAELLVRHGASVNVADLWKFTPL 754
GH+ + ++L+ HGA +N DL TP
Sbjct: 87 GHWAIVDMLLSHGADLNAVDLLGQTPF 7
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000365936 | hsapiens_gene_ensembl |
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit (EC
3.1.3.16) (PP-1A). [Source:Uniprot/SWISSPROT;Acc:P62136]
(330 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
01173 592 e-170
06264 574 e-164
19040 298 2e-81
08242 275 1e-74
18336 171 3e-61
06084 230 5e-61
04295 157 5e-39
25536 150 1e-36
21146 64 6e-11
30980 63 1e-10
36367 55 3e-08
18967 54 8e-08
17953 41 8e-04
01222 27 9.5
>01173
Length = 2619
Score = 592 bits (1527), Expect = e-170, Method: Compositional matrix adjust.
Identities = 288/304 (94%), Positives = 293/304 (96%)
Frame = -1
Query: 26 KNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPES 85
KNVQLTE+EIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPES
Sbjct: 2619 KNVQLTESEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPES 2440
Query: 86 NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYN 145
NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYN
Sbjct: 2439 NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYN 2260
Query: 146 IKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLL 205
IKLWKTFTDCFNCLPIAAI+DEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLL
Sbjct: 2259 IKLWKTFTDCFNCLPIAAIIDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLL 2080
Query: 206 WSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVT 265
WSDPDK+ GWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVT
Sbjct: 2079 WSDPDKETMGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVT 1900
Query: 266 LFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNS 325
LFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADK K YG GLN GRP+TPPR +
Sbjct: 1899 LFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKKKFPYG---GLNQ-GRPVTPPRGN 1732
Query: 326 AKAK 329
AKAK
Sbjct: 1731 AKAK 1720
>06264
Length = 999
Score = 574 bits (1479), Expect = e-164, Method: Compositional matrix adjust.
Identities = 277/296 (93%), Positives = 283/296 (95%)
Frame = -3
Query: 34 EIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDY 93
EIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDY
Sbjct: 997 EIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDY 818
Query: 94 VDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFT 153
VDRG+QSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFT
Sbjct: 817 VDRGRQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFT 638
Query: 154 DCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDV 213
DCFNCLPIAAI+DEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDK+
Sbjct: 637 DCFNCLPIAAIIDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKET 458
Query: 214 QGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYC 273
GWGE+DRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYC
Sbjct: 457 MGWGESDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYC 278
Query: 274 GEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAK 329
GEFDNAGAMMSVDETLMCSFQILKPADK K YG S GRP+TPPR +AKAK
Sbjct: 277 GEFDNAGAMMSVDETLMCSFQILKPADKKKFPYGGLS----XGRPVTPPRGNAKAK 122
>19040
Length = 452
Score = 298 bits (764), Expect = 2e-81, Method: Compositional matrix adjust.
Identities = 141/150 (94%), Positives = 145/150 (96%)
Frame = -3
Query: 36 RGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVD 95
RGLCLKSREIFL QPILLELEAPL ICGDIHGQY DLLRLFEYGGFPP +NYLFLGDYVD
Sbjct: 450 RGLCLKSREIFLQQPILLELEAPLIICGDIHGQYTDLLRLFEYGGFPPAANYLFLGDYVD 271
Query: 96 RGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDC 155
RGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYN+KLWKTFTDC
Sbjct: 270 RGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNVKLWKTFTDC 91
Query: 156 FNCLPIAAIVDEKIFCCHGGLSPDLQSMEQ 185
FNCLP+AAI+DEKIFCCHGGLSPDLQ MEQ
Sbjct: 90 FNCLPVAAIIDEKIFCCHGGLSPDLQGMEQ 1
>08242
Length = 3368
Score = 275 bits (704), Expect = 1e-74, Method: Compositional matrix adjust.
Identities = 127/257 (49%), Positives = 185/257 (71%), Gaps = 1/257 (0%)
Frame = -1
Query: 44 EIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLET 103
EI + + + +++P+ +CGDIHGQ+YDL LF+ GG P++NYLF+GD+VDRG S+ET
Sbjct: 3368 EILVEESNVQRVDSPVTVCGDIHGQFYDLKELFKVGGDVPDTNYLFMGDFVDRGFYSVET 3189
Query: 104 ICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRY-NIKLWKTFTDCFNCLPIA 162
LLLA K++YP+ L+RGNHE I ++YGFYDEC R+Y +I +W+ T+ F+ L ++
Sbjct: 3188 FLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLRKYGSITVWRYCTEIFDYLSLS 3009
Query: 163 AIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRG 222
AI+D KIFC HGGLSP +Q+++QIR I R +VP G +CDLLWSDP+ D+QGWG + RG
Sbjct: 3008 AIIDGKIFCVHGGLSPSIQTLDQIRSIDRKQEVPHDGPMCDLLWSDPE-DMQGWGVSPRG 2832
Query: 223 VSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAM 282
+ FG++VV++F + +DLICRAHQ+V +GY++ ++T++SAPNYC N A+
Sbjct: 2831 AGYLFGSDVVSQFNAANXIDLICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAI 2652
Query: 283 MSVDETLMCSFQILKPA 299
+ +DE L F I + A
Sbjct: 2651 LELDEHLQRDFTIFEAA 2601
>18336
Length = 465
Score = 171 bits (433), Expect(3) = 3e-61, Method: Compositional matrix adjust.
Identities = 86/111 (77%), Positives = 90/111 (81%)
Frame = +2
Query: 26 KNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPES 85
KNVQL+E + SR I L + + ICGDIHGQYYDLLRLFEYGGFPPES
Sbjct: 2 KNVQLSEQK*EAYV*ISRNI-LESAYSFRIRSTT*ICGDIHGQYYDLLRLFEYGGFPPES 178
Query: 86 NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGF 136
NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGF
Sbjct: 179 NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGF 331
Score = 74.3 bits (181), Expect(3) = 3e-61, Method: Compositional matrix adjust.
Identities = 32/34 (94%), Positives = 33/34 (97%)
Frame = +1
Query: 137 YDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIF 170
YDECKRRYNIKLWKTFTDCFNCLPIAAI+D KIF
Sbjct: 331 YDECKRRYNIKLWKTFTDCFNCLPIAAIIDVKIF 432
Score = 28.9 bits (63), Expect(3) = 3e-61, Method: Compositional matrix adjust.
Identities = 11/12 (91%), Positives = 11/12 (91%)
Frame = +3
Query: 170 FCCHGGLSPDLQ 181
CCHGGLSPDLQ
Sbjct: 429 LCCHGGLSPDLQ 464
>06084
Length = 1739
Score = 230 bits (587), Expect = 5e-61, Method: Compositional matrix adjust.
Identities = 119/262 (45%), Positives = 165/262 (62%), Gaps = 1/262 (0%)
Frame = -2
Query: 66 HGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNH 125
HGQ+YDL+ LF+ GG P++NY+F+GD+VDRG SLET LLL K K+P+ LLRGNH
Sbjct: 1738 HGQFYDLMELFKTGGEMPDTNYVFMGDFVDRGYFSLETFTLLLTLKAKWPDKIVLLRGNH 1559
Query: 126 ECASINRIYGFYDECKRRY-NIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSME 184
E I +IYGFYDEC+ +Y N W+ F+ L IAAI+DE I C HGGLSPD+++++
Sbjct: 1558 ESRQITQIYGFYDECQTKYGNANAWRYCCRVFDLLTIAAIIDECILCVHGGLSPDIKTID 1379
Query: 185 QIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLI 244
QIR I R ++P +G CDL+WSDP+ DV W + RG + FGA+V A+F+ ++L LI
Sbjct: 1378 QIRTIERNQEIPHKGAFCDLVWSDPE-DVDTWAMSPRGAGWLFGAKVTAEFVASNNLKLI 1202
Query: 245 CRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKG 304
CRAHQ+V +GY++ +LVT++SAPNYC N A++S + ++ K
Sbjct: 1201 CRAHQLVHEGYKYMFDEKLVTVWSAPNYCYRCGNIAAVLSFTDAEHHEAKLFKAV----- 1037
Query: 305 KYGQFSGLNPGGRPITPPRNSA 326
P + PPR
Sbjct: 1036 ---------PDSERVIPPRTQT 998
>04295
Length = 748
Score = 157 bits (398), Expect = 5e-39, Method: Compositional matrix adjust.
Identities = 78/95 (82%), Positives = 86/95 (90%)
Frame = -1
Query: 229 AEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDET 288
+VV+KFL++HDLDLI RAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAG MMSVDET
Sbjct: 748 GDVVSKFLNRHDLDLITRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDET 569
Query: 289 LMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPR 323
LMCSFQILKP++K K KY Q+ GLN GRPITPP+
Sbjct: 568 LMCSFQILKPSEK-KAKY-QYGGLN-SGRPITPPK 473
>25536
Length = 486
Score = 150 bits (378), Expect = 1e-36, Method: Compositional matrix adjust.
Identities = 64/127 (50%), Positives = 95/127 (74%), Gaps = 1/127 (0%)
Frame = +1
Query: 29 QLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYL 88
QL+EN+++ LC K++EI + + E++ P+ +CGD+HGQ++DL+ LF GG P++NYL
Sbjct: 106 QLSENQVKTLCEKAKEILSKESNVQEVKCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYL 285
Query: 89 FLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRY-NIK 147
F+GDYVDRG S+ET+ LL+A K+++ + +LRGNHE I ++YGFYDEC R+Y N
Sbjct: 286 FMGDYVDRGYYSVETVSLLVALKVRFRDRITILRGNHESRQITQVYGFYDECLRKYGNAN 465
Query: 148 LWKTFTD 154
+WK FTD
Sbjct: 466 VWKYFTD 486
>21146
Length = 408
Score = 64.3 bits (155), Expect = 6e-11, Method: Compositional matrix adjust.
Identities = 37/78 (47%), Positives = 46/78 (58%), Gaps = 3/78 (3%)
Frame = +3
Query: 198 QGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQ-VVEDGYE 256
QG +CDLLWSDPD D GWG + RG +TFG ++ F H + L LI RAHQ V+E +
Sbjct: 114 QGPMCDLLWSDPD-DRGGWGISPRGAGYTFGQDISETFNHSNGLTLISRAHQLVMEVMFW 290
Query: 257 FFAKRQLVTLF--SAPNY 272
F Q L+ S NY
Sbjct: 291 FVTGMQTCLLYELSLQNY 344
>30980
Length = 765
Score = 63.2 bits (152), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 31/68 (45%), Positives = 41/68 (60%)
Frame = +3
Query: 234 KFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSF 293
F H + L LI RAHQ+V +GY + R +VT+FSAPNYC N A+M +D+ L SF
Sbjct: 3 TFNHSNGLTLISRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDALKYSF 182
Query: 294 QILKPADK 301
PA +
Sbjct: 183 LQFDPAPR 206
>36367
Length = 827
Score = 55.5 bits (132), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 39/132 (29%), Positives = 66/132 (50%), Gaps = 20/132 (15%)
Frame = +1
Query: 173 HGGL-SPDLQS---MEQIRRIMRPTDVP--DQGLLCDLLWSDPD-------------KDV 213
HGG+ SP+ + +E I +I P P D + ++LWSDP K+
Sbjct: 1 HGGIPSPENEGGGHLEAINKIPVPLSDPEVDSPMAWEILWSDPISVDLVSPEVLKDMKEH 180
Query: 214 QGWGENDR-GVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNY 272
G+ N R G + F + FL ++ L + RAH+V E G++ + +L+T+FS+ Y
Sbjct: 181 HGFTFNSRRGTAHFFSCNALLAFLERNGLSHVIRAHEVQEVGFQVQQQGKLLTVFSSSRY 360
Query: 273 CGEFDNAGAMMS 284
CG + A +++
Sbjct: 361 CGGSNEAACVLA 396
>18967
Length = 440
Score = 53.9 bits (128), Expect = 8e-08, Method: Compositional matrix adjust.
Identities = 23/46 (50%), Positives = 34/46 (73%)
Frame = +2
Query: 241 LDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVD 286
LDLICRAHQ+V +G ++ + +LVT++SAPNYC N A++S +
Sbjct: 2 LDLICRAHQLVNEGIKYMFEGKLVTVWSAPNYCYRCGNVAAILSFE 139
>17953
Length = 626
Score = 40.8 bits (94), Expect = 8e-04, Method: Compositional matrix adjust.
Identities = 20/56 (35%), Positives = 32/56 (57%), Gaps = 6/56 (10%)
Frame = -2
Query: 236 LHKHDLDLICRAHQVVEDGYEFFAKRQ------LVTLFSAPNYCGEFDNAGAMMSV 285
L +++L I RAH+ + GY + K Q L+T+FSAPNY ++N ++S
Sbjct: 625 LQQNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKVQLLST 458
>01222
Length = 744
Score = 27.3 bits (59), Expect = 9.5, Method: Compositional matrix adjust.
Identities = 16/55 (29%), Positives = 27/55 (49%), Gaps = 1/55 (1%)
Frame = -2
Query: 119 FLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLP-IAAIVDEKIFCC 172
F + NH C S ++Y + + NIKLW + C+ + V+E++F C
Sbjct: 707 FTIHSNHICRSRRKLYTEINPQHVKINIKLWHPTQFFYLCIMYVCRRVNEQVFVC 543
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000309474 | hsapiens_gene_ensembl | 26S proteasome
non-ATPase regulatory subunit 1 (26S proteasome regulatory subunit
RPN2) (26S proteasome regulatory subunit S1) (26S proteasome subunit
p112). [Source:Uniprot/SWISSPROT;Acc:Q99460]
(953 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
32303 476 e-169
02455 116 4e-26
00896 66 8e-11
34335 47 3e-05
>32303
Length = 1266
Score = 476 bits (1224), Expect(3) = e-169, Method: Compositional matrix adjust.
Identities = 220/274 (80%), Positives = 250/274 (91%)
Frame = -3
Query: 537 QETQHEKILRGLAVGIALVMYGRMEEADALIESLCRDKDPILRRSGMYTVAMAYCGSGNN 596
+ TQHEKILRGLAVGIAL MYGRMEEADAL+ESL RDKDPILR +GMYT+AMAYCGSGNN
Sbjct: 874 RTTQHEKILRGLAVGIALTMYGRMEEADALVESLTRDKDPILRWAGMYTLAMAYCGSGNN 695
Query: 597 KAIRRLLHVAVSDVNDDVRRAAVESLGFILFRTPEQCPSVVSLLSESYNPHVRYGAAMAL 656
+AIRRLLHVAVSDVNDDVRR AV SLGF+LFRTPEQCPSVVSLLSESYNPHVR+GAAMAL
Sbjct: 694 QAIRRLLHVAVSDVNDDVRRVAVTSLGFLLFRTPEQCPSVVSLLSESYNPHVRFGAAMAL 515
Query: 657 GICCAGTGNKEAINLLEPMTNDPVNYVRQGALIASALIMIQQTEITCPKVNQFRQLYSKV 716
GI CAG+G KEA+ LLEPMTNDPVNYVRQGALIASALI+IQ E++CPKV FRQLY+KV
Sbjct: 514 GIACAGSGLKEAMALLEPMTNDPVNYVRQGALIASALILIQHNEVSCPKVTHFRQLYAKV 335
Query: 717 INDKHDDVMAKFGAILAQGILDAGGHNVTISLQSRTGHTHMPSVVGVLVFTQFWFWFPLS 776
I+DKH+DVMAKFGAILAQGI+DAGG N T+SLQSRTGHT+M +VVG+LVF QFW+W+PL+
Sbjct: 334 ISDKHEDVMAKFGAILAQGIIDAGGRNCTVSLQSRTGHTNMDAVVGLLVFCQFWYWYPLT 155
Query: 777 HFLSLAYTPTCVIGLNKDLKMPKVQYKSNCKPST 810
HFLSLA++P C++GLN DLKMPKV S+ +P +
Sbjct: 154 HFLSLAFSPACIVGLNADLKMPKV---SSSRPGS 62
Score = 101 bits (252), Expect(3) = e-169, Method: Composition-based stats.
Identities = 45/56 (80%), Positives = 49/56 (87%)
Frame = -1
Query: 407 SLGVIHKGHEKEALQLMATYLPKDTSPGSAYQEGGGLYALGLIHANHGGDIIDYLL 462
SLG IH GHEKEAL LM++YLPKDT+ GSAY EGGGLYALGLIHANHGG I +YLL
Sbjct: 1266 SLGCIHHGHEKEALNLMSSYLPKDTTAGSAYSEGGGLYALGLIHANHGGQITEYLL 1099
Score = 59.3 bits (142), Expect(3) = e-169, Method: Compositional matrix adjust.
Identities = 33/85 (38%), Positives = 40/85 (47%)
Frame = -2
Query: 454 GGDIIDYLLNQLKNASNDIVRHXXXXXXXXXXXXXXRQDVYDLLKTNLYQDDXXXXXXXX 513
GG QLK+AS D+VRH RQD+Y+ LK NLYQDD
Sbjct: 1124 GGRSPSTSWGQLKDASTDMVRHGGCLGLGLAAMGTARQDIYEQLKFNLYQDDAVTGEAAG 945
Query: 514 XXXXXXXXXSKNAQAIEDMVGYAQE 538
+K+ AIEDMV YAQ+
Sbjct: 944 LAMGLVMLGTKSTPAIEDMVAYAQD 870
>02455
Length = 832
Score = 116 bits (291), Expect = 4e-26, Method: Compositional matrix adjust.
Identities = 49/82 (59%), Positives = 63/82 (76%)
Frame = -1
Query: 755 THMPSVVGVLVFTQFWFWFPLSHFLSLAYTPTCVIGLNKDLKMPKVQYKSNCKPSTFAYP 814
T+M +VVG+LVF QFW+W+PL+HFLSLA++P C++GLN DLKMPKV++KS+ KPS +AYP
Sbjct: 832 TNMDAVVGLLVFCQFWYWYPLTHFLSLAFSPACIVGLNADLKMPKVEFKSSGKPSLYAYP 653
Query: 815 APLXXXXXXXXXXXSTAVLSIT 836
PL TAVLSIT
Sbjct: 652 PPLEEKKNQTKEKVETAVLSIT 587
Score = 66.6 bits (161), Expect = 4e-11, Method: Compositional matrix adjust.
Identities = 36/61 (59%), Positives = 45/61 (73%), Gaps = 1/61 (1%)
Frame = -1
Query: 875 FQLLDNPARVMPAQLKVLTMPETCRYQPFKPLSIGGIIILKDTS-EDIEELVEPVAAHGP 933
F+LL NPARVM QL+VL+ E RY+P K LS GGI+ILK+ + E+ E+LVE V A GP
Sbjct: 349 FELLSNPARVMKNQLRVLSSSEGSRYRPVKDLSHGGIVILKNVNPEEEEDLVEFVQAGGP 170
Query: 934 K 934
K
Sbjct: 169 K 167
>00896
Length = 2317
Score = 65.9 bits (159), Expect = 8e-11, Method: Compositional matrix adjust.
Identities = 36/61 (59%), Positives = 45/61 (73%), Gaps = 1/61 (1%)
Frame = -3
Query: 875 FQLLDNPARVMPAQLKVLTMPETCRYQPFKPLSIGGIIILKDTS-EDIEELVEPVAAHGP 933
F+LL NPARVM QL+VL+ E RY+P K LS GGI+ILK+ + E+ E+LVE V A GP
Sbjct: 1595 FELLSNPARVMKNQLRVLSSSEGSRYRPVKDLSHGGIVILKNVNPEEEEDLVEFVQAGGP 1416
Query: 934 K 934
K
Sbjct: 1415 K 1413
>34335
Length = 561
Score = 47.4 bits (111), Expect = 3e-05, Method: Composition-based stats.
Identities = 22/26 (84%), Positives = 23/26 (88%)
Frame = +2
Query: 583 MYTVAMAYCGSGNNKAIRRLLHVAVS 608
MYT MAYCGSGNN+AIRRLLHV VS
Sbjct: 23 MYT--MAYCGSGNNQAIRRLLHVVVS 94
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000326031 | hsapiens_gene_ensembl |
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit (EC
3.1.3.16) (PP-1A). [Source:Uniprot/SWISSPROT;Acc:P62136]
(341 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
01173 591 e-169
06264 573 e-164
19040 298 2e-81
08242 276 1e-74
18336 171 3e-61
06084 230 6e-61
04295 157 5e-39
25536 149 1e-36
21146 64 7e-11
30980 63 1e-10
36367 55 3e-08
18967 54 9e-08
17953 41 7e-04
>01173
Length = 2619
Score = 591 bits (1524), Expect = e-169, Method: Compositional matrix adjust.
Identities = 288/304 (94%), Positives = 293/304 (96%)
Frame = -1
Query: 37 KNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPES 96
KNVQLTE+EIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPES
Sbjct: 2619 KNVQLTESEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPES 2440
Query: 97 NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYN 156
NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYN
Sbjct: 2439 NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYN 2260
Query: 157 IKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLL 216
IKLWKTFTDCFNCLPIAAI+DEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLL
Sbjct: 2259 IKLWKTFTDCFNCLPIAAIIDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLL 2080
Query: 217 WSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVT 276
WSDPDK+ GWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVT
Sbjct: 2079 WSDPDKETMGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVT 1900
Query: 277 LFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNS 336
LFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADK K YG GLN GRP+TPPR +
Sbjct: 1899 LFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKKKFPYG---GLNQ-GRPVTPPRGN 1732
Query: 337 AKAK 340
AKAK
Sbjct: 1731 AKAK 1720
>06264
Length = 999
Score = 573 bits (1478), Expect = e-164, Method: Compositional matrix adjust.
Identities = 277/296 (93%), Positives = 283/296 (95%)
Frame = -3
Query: 45 EIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDY 104
EIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDY
Sbjct: 997 EIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDY 818
Query: 105 VDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFT 164
VDRG+QSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFT
Sbjct: 817 VDRGRQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFT 638
Query: 165 DCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDV 224
DCFNCLPIAAI+DEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDK+
Sbjct: 637 DCFNCLPIAAIIDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKET 458
Query: 225 QGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYC 284
GWGE+DRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYC
Sbjct: 457 MGWGESDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYC 278
Query: 285 GEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAK 340
GEFDNAGAMMSVDETLMCSFQILKPADK K YG S GRP+TPPR +AKAK
Sbjct: 277 GEFDNAGAMMSVDETLMCSFQILKPADKKKFPYGGLS----XGRPVTPPRGNAKAK 122
>19040
Length = 452
Score = 298 bits (764), Expect = 2e-81, Method: Compositional matrix adjust.
Identities = 141/150 (94%), Positives = 145/150 (96%)
Frame = -3
Query: 47 RGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVD 106
RGLCLKSREIFL QPILLELEAPL ICGDIHGQY DLLRLFEYGGFPP +NYLFLGDYVD
Sbjct: 450 RGLCLKSREIFLQQPILLELEAPLIICGDIHGQYTDLLRLFEYGGFPPAANYLFLGDYVD 271
Query: 107 RGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDC 166
RGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYN+KLWKTFTDC
Sbjct: 270 RGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNVKLWKTFTDC 91
Query: 167 FNCLPIAAIVDEKIFCCHGGLSPDLQSMEQ 196
FNCLP+AAI+DEKIFCCHGGLSPDLQ MEQ
Sbjct: 90 FNCLPVAAIIDEKIFCCHGGLSPDLQGMEQ 1
>08242
Length = 3368
Score = 276 bits (705), Expect = 1e-74, Method: Compositional matrix adjust.
Identities = 127/257 (49%), Positives = 185/257 (71%), Gaps = 1/257 (0%)
Frame = -1
Query: 55 EIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLET 114
EI + + + +++P+ +CGDIHGQ+YDL LF+ GG P++NYLF+GD+VDRG S+ET
Sbjct: 3368 EILVEESNVQRVDSPVTVCGDIHGQFYDLKELFKVGGDVPDTNYLFMGDFVDRGFYSVET 3189
Query: 115 ICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRY-NIKLWKTFTDCFNCLPIA 173
LLLA K++YP+ L+RGNHE I ++YGFYDEC R+Y +I +W+ T+ F+ L ++
Sbjct: 3188 FLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLRKYGSITVWRYCTEIFDYLSLS 3009
Query: 174 AIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRG 233
AI+D KIFC HGGLSP +Q+++QIR I R +VP G +CDLLWSDP+ D+QGWG + RG
Sbjct: 3008 AIIDGKIFCVHGGLSPSIQTLDQIRSIDRKQEVPHDGPMCDLLWSDPE-DMQGWGVSPRG 2832
Query: 234 VSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAM 293
+ FG++VV++F + +DLICRAHQ+V +GY++ ++T++SAPNYC N A+
Sbjct: 2831 AGYLFGSDVVSQFNAANXIDLICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAI 2652
Query: 294 MSVDETLMCSFQILKPA 310
+ +DE L F I + A
Sbjct: 2651 LELDEHLQRDFTIFEAA 2601
>18336
Length = 465
Score = 171 bits (434), Expect(3) = 3e-61, Method: Compositional matrix adjust.
Identities = 86/111 (77%), Positives = 90/111 (81%)
Frame = +2
Query: 37 KNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPES 96
KNVQL+E + SR I L + + ICGDIHGQYYDLLRLFEYGGFPPES
Sbjct: 2 KNVQLSEQK*EAYV*ISRNI-LESAYSFRIRSTT*ICGDIHGQYYDLLRLFEYGGFPPES 178
Query: 97 NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGF 147
NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGF
Sbjct: 179 NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGF 331
Score = 74.3 bits (181), Expect(3) = 3e-61, Method: Compositional matrix adjust.
Identities = 32/34 (94%), Positives = 33/34 (97%)
Frame = +1
Query: 148 YDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIF 181
YDECKRRYNIKLWKTFTDCFNCLPIAAI+D KIF
Sbjct: 331 YDECKRRYNIKLWKTFTDCFNCLPIAAIIDVKIF 432
Score = 28.5 bits (62), Expect(3) = 3e-61, Method: Compositional matrix adjust.
Identities = 11/12 (91%), Positives = 11/12 (91%)
Frame = +3
Query: 181 FCCHGGLSPDLQ 192
CCHGGLSPDLQ
Sbjct: 429 LCCHGGLSPDLQ 464
>06084
Length = 1739
Score = 230 bits (587), Expect = 6e-61, Method: Compositional matrix adjust.
Identities = 119/262 (45%), Positives = 165/262 (62%), Gaps = 1/262 (0%)
Frame = -2
Query: 77 HGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNH 136
HGQ+YDL+ LF+ GG P++NY+F+GD+VDRG SLET LLL K K+P+ LLRGNH
Sbjct: 1738 HGQFYDLMELFKTGGEMPDTNYVFMGDFVDRGYFSLETFTLLLTLKAKWPDKIVLLRGNH 1559
Query: 137 ECASINRIYGFYDECKRRY-NIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSME 195
E I +IYGFYDEC+ +Y N W+ F+ L IAAI+DE I C HGGLSPD+++++
Sbjct: 1558 ESRQITQIYGFYDECQTKYGNANAWRYCCRVFDLLTIAAIIDECILCVHGGLSPDIKTID 1379
Query: 196 QIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLI 255
QIR I R ++P +G CDL+WSDP+ DV W + RG + FGA+V A+F+ ++L LI
Sbjct: 1378 QIRTIERNQEIPHKGAFCDLVWSDPE-DVDTWAMSPRGAGWLFGAKVTAEFVASNNLKLI 1202
Query: 256 CRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKG 315
CRAHQ+V +GY++ +LVT++SAPNYC N A++S + ++ K
Sbjct: 1201 CRAHQLVHEGYKYMFDEKLVTVWSAPNYCYRCGNIAAVLSFTDAEHHEAKLFKAV----- 1037
Query: 316 KYGQFSGLNPGGRPITPPRNSA 337
P + PPR
Sbjct: 1036 ---------PDSERVIPPRTQT 998
>04295
Length = 748
Score = 157 bits (398), Expect = 5e-39, Method: Compositional matrix adjust.
Identities = 78/95 (82%), Positives = 86/95 (90%)
Frame = -1
Query: 240 AEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDET 299
+VV+KFL++HDLDLI RAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAG MMSVDET
Sbjct: 748 GDVVSKFLNRHDLDLITRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDET 569
Query: 300 LMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPR 334
LMCSFQILKP++K K KY Q+ GLN GRPITPP+
Sbjct: 568 LMCSFQILKPSEK-KAKY-QYGGLN-SGRPITPPK 473
>25536
Length = 486
Score = 149 bits (377), Expect = 1e-36, Method: Compositional matrix adjust.
Identities = 64/127 (50%), Positives = 95/127 (74%), Gaps = 1/127 (0%)
Frame = +1
Query: 40 QLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYL 99
QL+EN+++ LC K++EI + + E++ P+ +CGD+HGQ++DL+ LF GG P++NYL
Sbjct: 106 QLSENQVKTLCEKAKEILSKESNVQEVKCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYL 285
Query: 100 FLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRY-NIK 158
F+GDYVDRG S+ET+ LL+A K+++ + +LRGNHE I ++YGFYDEC R+Y N
Sbjct: 286 FMGDYVDRGYYSVETVSLLVALKVRFRDRITILRGNHESRQITQVYGFYDECLRKYGNAN 465
Query: 159 LWKTFTD 165
+WK FTD
Sbjct: 466 VWKYFTD 486
>21146
Length = 408
Score = 64.3 bits (155), Expect = 7e-11, Method: Compositional matrix adjust.
Identities = 37/78 (47%), Positives = 46/78 (58%), Gaps = 3/78 (3%)
Frame = +3
Query: 209 QGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQ-VVEDGYE 267
QG +CDLLWSDPD D GWG + RG +TFG ++ F H + L LI RAHQ V+E +
Sbjct: 114 QGPMCDLLWSDPD-DRGGWGISPRGAGYTFGQDISETFNHSNGLTLISRAHQLVMEVMFW 290
Query: 268 FFAKRQLVTLF--SAPNY 283
F Q L+ S NY
Sbjct: 291 FVTGMQTCLLYELSLQNY 344
>30980
Length = 765
Score = 63.2 bits (152), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 31/68 (45%), Positives = 41/68 (60%)
Frame = +3
Query: 245 KFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSF 304
F H + L LI RAHQ+V +GY + R +VT+FSAPNYC N A+M +D+ L SF
Sbjct: 3 TFNHSNGLTLISRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDALKYSF 182
Query: 305 QILKPADK 312
PA +
Sbjct: 183 LQFDPAPR 206
>36367
Length = 827
Score = 55.5 bits (132), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 39/132 (29%), Positives = 66/132 (50%), Gaps = 20/132 (15%)
Frame = +1
Query: 184 HGGL-SPDLQS---MEQIRRIMRPTDVP--DQGLLCDLLWSDPD-------------KDV 224
HGG+ SP+ + +E I +I P P D + ++LWSDP K+
Sbjct: 1 HGGIPSPENEGGGHLEAINKIPVPLSDPEVDSPMAWEILWSDPISVDLVSPEVLKDMKEH 180
Query: 225 QGWGENDR-GVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNY 283
G+ N R G + F + FL ++ L + RAH+V E G++ + +L+T+FS+ Y
Sbjct: 181 HGFTFNSRRGTAHFFSCNALLAFLERNGLSHVIRAHEVQEVGFQVQQQGKLLTVFSSSRY 360
Query: 284 CGEFDNAGAMMS 295
CG + A +++
Sbjct: 361 CGGSNEAACVLA 396
>18967
Length = 440
Score = 53.9 bits (128), Expect = 9e-08, Method: Compositional matrix adjust.
Identities = 23/46 (50%), Positives = 34/46 (73%)
Frame = +2
Query: 252 LDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVD 297
LDLICRAHQ+V +G ++ + +LVT++SAPNYC N A++S +
Sbjct: 2 LDLICRAHQLVNEGIKYMFEGKLVTVWSAPNYCYRCGNVAAILSFE 139
>17953
Length = 626
Score = 40.8 bits (94), Expect = 7e-04, Method: Compositional matrix adjust.
Identities = 20/56 (35%), Positives = 32/56 (57%), Gaps = 6/56 (10%)
Frame = -2
Query: 247 LHKHDLDLICRAHQVVEDGYEFFAKRQ------LVTLFSAPNYCGEFDNAGAMMSV 296
L +++L I RAH+ + GY + K Q L+T+FSAPNY ++N ++S
Sbjct: 625 LQQNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKVQLLST 458
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000335084 | hsapiens_gene_ensembl |
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (EC
3.1.3.16) (PP-1G) (Protein phosphatase 1C catalytic subunit).
[Source:Uniprot/SWISSPROT;Acc:P36873]
(323 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
01173 582 e-167
06264 565 e-161
19040 299 9e-82
08242 273 5e-74
06084 233 1e-61
18336 171 3e-61
04295 152 2e-37
25536 149 2e-36
30980 67 7e-12
21146 64 7e-11
36367 55 5e-08
18967 54 8e-08
17953 41 8e-04
09604 27 7.6
01222 27 9.8
>01173
Length = 2619
Score = 582 bits (1501), Expect = e-167, Method: Compositional matrix adjust.
Identities = 281/302 (93%), Positives = 287/302 (95%), Gaps = 5/302 (1%)
Frame = -1
Query: 26 KNVQLQENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPES 85
KNVQL E+EIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPES
Sbjct: 2619 KNVQLTESEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPES 2440
Query: 86 NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYN 145
NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYN
Sbjct: 2439 NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYN 2260
Query: 146 IKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLL 205
IKLWKTFTDCFNCLPIAAI+DEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLL
Sbjct: 2259 IKLWKTFTDCFNCLPIAAIIDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLL 2080
Query: 206 WSDPDKDVLGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVT 265
WSDPDK+ +GWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVT
Sbjct: 2079 WSDPDKETMGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVT 1900
Query: 266 LFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPAEKKK-----PNATRPVTPPRGMITKQ 320
LFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPA+KKK N RPVTPPRG +
Sbjct: 1899 LFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKKKFPYGGLNQGRPVTPPRGNAKAK 1720
Query: 321 AK 322
K
Sbjct: 1719 GK 1714
>06264
Length = 999
Score = 565 bits (1455), Expect = e-161, Method: Compositional matrix adjust.
Identities = 272/294 (92%), Positives = 280/294 (95%), Gaps = 5/294 (1%)
Frame = -3
Query: 34 EIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDY 93
EIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDY
Sbjct: 997 EIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDY 818
Query: 94 VDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFT 153
VDRG+QSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFT
Sbjct: 817 VDRGRQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFT 638
Query: 154 DCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDV 213
DCFNCLPIAAI+DEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDK+
Sbjct: 637 DCFNCLPIAAIIDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKET 458
Query: 214 LGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYC 273
+GWGE+DRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYC
Sbjct: 457 MGWGESDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYC 278
Query: 274 GEFDNAGAMMSVDETLMCSFQILKPAEKKK-----PNATRPVTPPRGMITKQAK 322
GEFDNAGAMMSVDETLMCSFQILKPA+KKK + RPVTPPRG + K
Sbjct: 277 GEFDNAGAMMSVDETLMCSFQILKPADKKKFPYGGLSXGRPVTPPRGNAKAKGK 116
>19040
Length = 452
Score = 299 bits (766), Expect = 9e-82, Method: Compositional matrix adjust.
Identities = 141/150 (94%), Positives = 145/150 (96%)
Frame = -3
Query: 36 RGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVD 95
RGLCLKSREIFL QPILLELEAPL ICGDIHGQY DLLRLFEYGGFPP +NYLFLGDYVD
Sbjct: 450 RGLCLKSREIFLQQPILLELEAPLIICGDIHGQYTDLLRLFEYGGFPPAANYLFLGDYVD 271
Query: 96 RGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDC 155
RGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYN+KLWKTFTDC
Sbjct: 270 RGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNVKLWKTFTDC 91
Query: 156 FNCLPIAAIVDEKIFCCHGGLSPDLQSMEQ 185
FNCLP+AAI+DEKIFCCHGGLSPDLQ MEQ
Sbjct: 90 FNCLPVAAIIDEKIFCCHGGLSPDLQGMEQ 1
>08242
Length = 3368
Score = 273 bits (699), Expect = 5e-74, Method: Compositional matrix adjust.
Identities = 128/269 (47%), Positives = 189/269 (70%), Gaps = 3/269 (1%)
Frame = -1
Query: 44 EIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLET 103
EI + + + +++P+ +CGDIHGQ+YDL LF+ GG P++NYLF+GD+VDRG S+ET
Sbjct: 3368 EILVEESNVQRVDSPVTVCGDIHGQFYDLKELFKVGGDVPDTNYLFMGDFVDRGFYSVET 3189
Query: 104 ICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRY-NIKLWKTFTDCFNCLPIA 162
LLLA K++YP+ L+RGNHE I ++YGFYDEC R+Y +I +W+ T+ F+ L ++
Sbjct: 3188 FLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLRKYGSITVWRYCTEIFDYLSLS 3009
Query: 163 AIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVLGWGENDRG 222
AI+D KIFC HGGLSP +Q+++QIR I R +VP G +CDLLWSDP+ D+ GWG + RG
Sbjct: 3008 AIIDGKIFCVHGGLSPSIQTLDQIRSIDRKQEVPHDGPMCDLLWSDPE-DMQGWGVSPRG 2832
Query: 223 VSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAM 282
+ FG++VV++F + +DLICRAHQ+V +GY++ ++T++SAPNYC N A+
Sbjct: 2831 AGYLFGSDVVSQFNAANXIDLICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAI 2652
Query: 283 MSVDETLMCSFQILK--PAEKKKPNATRP 309
+ +DE L F I + P E + + +P
Sbjct: 2651 LELDEHLQRDFTIFEAAPQEARGIPSKKP 2565
>06084
Length = 1739
Score = 233 bits (593), Expect = 1e-61, Method: Compositional matrix adjust.
Identities = 121/250 (48%), Positives = 168/250 (67%), Gaps = 1/250 (0%)
Frame = -2
Query: 66 HGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNH 125
HGQ+YDL+ LF+ GG P++NY+F+GD+VDRG SLET LLL K K+P+ LLRGNH
Sbjct: 1738 HGQFYDLMELFKTGGEMPDTNYVFMGDFVDRGYFSLETFTLLLTLKAKWPDKIVLLRGNH 1559
Query: 126 ECASINRIYGFYDECKRRY-NIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSME 184
E I +IYGFYDEC+ +Y N W+ F+ L IAAI+DE I C HGGLSPD+++++
Sbjct: 1558 ESRQITQIYGFYDECQTKYGNANAWRYCCRVFDLLTIAAIIDECILCVHGGLSPDIKTID 1379
Query: 185 QIRRIMRPTDVPDQGLLCDLLWSDPDKDVLGWGENDRGVSFTFGAEVVAKFLHKHDLDLI 244
QIR I R ++P +G CDL+WSDP+ DV W + RG + FGA+V A+F+ ++L LI
Sbjct: 1378 QIRTIERNQEIPHKGAFCDLVWSDPE-DVDTWAMSPRGAGWLFGAKVTAEFVASNNLKLI 1202
Query: 245 CRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPAEKKKP 304
CRAHQ+V +GY++ +LVT++SAPNYC N A++S + ++ K P
Sbjct: 1201 CRAHQLVHEGYKYMFDEKLVTVWSAPNYCYRCGNIAAVLSFTDAEHHEAKLFKAV----P 1034
Query: 305 NATRPVTPPR 314
++ R V PPR
Sbjct: 1033 DSER-VIPPR 1007
>18336
Length = 465
Score = 171 bits (433), Expect(3) = 3e-61, Method: Compositional matrix adjust.
Identities = 86/111 (77%), Positives = 89/111 (80%)
Frame = +2
Query: 26 KNVQLQENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPES 85
KNVQL E + SR I L + + ICGDIHGQYYDLLRLFEYGGFPPES
Sbjct: 2 KNVQLSEQK*EAYV*ISRNI-LESAYSFRIRSTT*ICGDIHGQYYDLLRLFEYGGFPPES 178
Query: 86 NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGF 136
NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGF
Sbjct: 179 NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGF 331
Score = 73.9 bits (180), Expect(3) = 3e-61, Method: Compositional matrix adjust.
Identities = 32/34 (94%), Positives = 33/34 (97%)
Frame = +1
Query: 137 YDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIF 170
YDECKRRYNIKLWKTFTDCFNCLPIAAI+D KIF
Sbjct: 331 YDECKRRYNIKLWKTFTDCFNCLPIAAIIDVKIF 432
Score = 28.9 bits (63), Expect(3) = 3e-61, Method: Compositional matrix adjust.
Identities = 11/12 (91%), Positives = 11/12 (91%)
Frame = +3
Query: 170 FCCHGGLSPDLQ 181
CCHGGLSPDLQ
Sbjct: 429 LCCHGGLSPDLQ 464
>04295
Length = 748
Score = 152 bits (384), Expect = 2e-37, Method: Compositional matrix adjust.
Identities = 72/92 (78%), Positives = 80/92 (86%), Gaps = 6/92 (6%)
Frame = -1
Query: 229 AEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDET 288
+VV+KFL++HDLDLI RAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAG MMSVDET
Sbjct: 748 GDVVSKFLNRHDLDLITRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDET 569
Query: 289 LMCSFQILKPAEKKKP------NATRPVTPPR 314
LMCSFQILKP+EKK N+ RP+TPP+
Sbjct: 568 LMCSFQILKPSEKKAKYQYGGLNSGRPITPPK 473
>25536
Length = 486
Score = 149 bits (376), Expect = 2e-36, Method: Compositional matrix adjust.
Identities = 64/127 (50%), Positives = 94/127 (74%), Gaps = 1/127 (0%)
Frame = +1
Query: 29 QLQENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYL 88
QL EN+++ LC K++EI + + E++ P+ +CGD+HGQ++DL+ LF GG P++NYL
Sbjct: 106 QLSENQVKTLCEKAKEILSKESNVQEVKCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYL 285
Query: 89 FLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRY-NIK 147
F+GDYVDRG S+ET+ LL+A K+++ + +LRGNHE I ++YGFYDEC R+Y N
Sbjct: 286 FMGDYVDRGYYSVETVSLLVALKVRFRDRITILRGNHESRQITQVYGFYDECLRKYGNAN 465
Query: 148 LWKTFTD 154
+WK FTD
Sbjct: 466 VWKYFTD 486
>30980
Length = 765
Score = 67.4 bits (163), Expect = 7e-12, Method: Compositional matrix adjust.
Identities = 34/75 (45%), Positives = 47/75 (62%), Gaps = 1/75 (1%)
Frame = +3
Query: 235 FLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQ 294
F H + L LI RAHQ+V +GY + R +VT+FSAPNYC N A+M +D+ L SF
Sbjct: 6 FNHSNGLTLISRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDALKYSFL 185
Query: 295 ILKPAEKK-KPNATR 308
PA ++ +P+ TR
Sbjct: 186 QFDPAPRRGEPHVTR 230
>21146
Length = 408
Score = 64.3 bits (155), Expect = 7e-11, Method: Compositional matrix adjust.
Identities = 37/78 (47%), Positives = 46/78 (58%), Gaps = 3/78 (3%)
Frame = +3
Query: 198 QGLLCDLLWSDPDKDVLGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQ-VVEDGYE 256
QG +CDLLWSDPD D GWG + RG +TFG ++ F H + L LI RAHQ V+E +
Sbjct: 114 QGPMCDLLWSDPD-DRGGWGISPRGAGYTFGQDISETFNHSNGLTLISRAHQLVMEVMFW 290
Query: 257 FFAKRQLVTLF--SAPNY 272
F Q L+ S NY
Sbjct: 291 FVTGMQTCLLYELSLQNY 344
>36367
Length = 827
Score = 54.7 bits (130), Expect = 5e-08, Method: Compositional matrix adjust.
Identities = 39/132 (29%), Positives = 66/132 (50%), Gaps = 20/132 (15%)
Frame = +1
Query: 173 HGGL-SPDLQS---MEQIRRIMRPTDVP--DQGLLCDLLWSDPD-------------KDV 213
HGG+ SP+ + +E I +I P P D + ++LWSDP K+
Sbjct: 1 HGGIPSPENEGGGHLEAINKIPVPLSDPEVDSPMAWEILWSDPISVDLVSPEVLKDMKEH 180
Query: 214 LGWGENDR-GVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNY 272
G+ N R G + F + FL ++ L + RAH+V E G++ + +L+T+FS+ Y
Sbjct: 181 HGFTFNSRRGTAHFFSCNALLAFLERNGLSHVIRAHEVQEVGFQVQQQGKLLTVFSSSRY 360
Query: 273 CGEFDNAGAMMS 284
CG + A +++
Sbjct: 361 CGGSNEAACVLA 396
>18967
Length = 440
Score = 53.9 bits (128), Expect = 8e-08, Method: Compositional matrix adjust.
Identities = 23/46 (50%), Positives = 34/46 (73%)
Frame = +2
Query: 241 LDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVD 286
LDLICRAHQ+V +G ++ + +LVT++SAPNYC N A++S +
Sbjct: 2 LDLICRAHQLVNEGIKYMFEGKLVTVWSAPNYCYRCGNVAAILSFE 139
>17953
Length = 626
Score = 40.8 bits (94), Expect = 8e-04, Method: Compositional matrix adjust.
Identities = 20/56 (35%), Positives = 32/56 (57%), Gaps = 6/56 (10%)
Frame = -2
Query: 236 LHKHDLDLICRAHQVVEDGYEFFAKRQ------LVTLFSAPNYCGEFDNAGAMMSV 285
L +++L I RAH+ + GY + K Q L+T+FSAPNY ++N ++S
Sbjct: 625 LQQNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKVQLLST 458
>09604
Length = 1098
Score = 27.3 bits (59), Expect = 7.6, Method: Compositional matrix adjust.
Identities = 11/30 (36%), Positives = 18/30 (60%)
Frame = +3
Query: 289 LMCSFQILKPAEKKKPNATRPVTPPRGMIT 318
L+CSFQ+ K K++ +TRP + + T
Sbjct: 846 LLCSFQVSKNKTKRRKRSTRPFKGNQNLCT 935
>01222
Length = 744
Score = 26.9 bits (58), Expect = 9.8, Method: Compositional matrix adjust.
Identities = 16/55 (29%), Positives = 27/55 (49%), Gaps = 1/55 (1%)
Frame = -2
Query: 119 FLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNC-LPIAAIVDEKIFCC 172
F + NH C S ++Y + + NIKLW + C + + V+E++F C
Sbjct: 707 FTIHSNHICRSRRKLYTEINPQHVKINIKLWHPTQFFYLCIMYVCRRVNEQVFVC 543
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000341779 | hsapiens_gene_ensembl |
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (EC
3.1.3.16) (PP-1G) (Protein phosphatase 1C catalytic subunit).
[Source:Uniprot/SWISSPROT;Acc:P36873]
(337 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
01173 578 e-166
06264 562 e-161
19040 299 9e-82
08242 274 5e-74
06084 233 7e-62
18336 171 4e-61
04295 152 2e-37
25536 149 2e-36
30980 67 8e-12
21146 64 8e-11
36367 55 6e-08
18967 54 9e-08
17953 40 0.001
>01173
Length = 2619
Score = 578 bits (1491), Expect = e-166, Method: Compositional matrix adjust.
Identities = 279/294 (94%), Positives = 284/294 (96%), Gaps = 5/294 (1%)
Frame = -1
Query: 26 KNVQLQENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPES 85
KNVQL E+EIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPES
Sbjct: 2619 KNVQLTESEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPES 2440
Query: 86 NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYN 145
NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYN
Sbjct: 2439 NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYN 2260
Query: 146 IKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLL 205
IKLWKTFTDCFNCLPIAAI+DEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLL
Sbjct: 2259 IKLWKTFTDCFNCLPIAAIIDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLL 2080
Query: 206 WSDPDKDVLGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVT 265
WSDPDK+ +GWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVT
Sbjct: 2079 WSDPDKETMGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVT 1900
Query: 266 LFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPAEKKK-----PNATRPVTPPR 314
LFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPA+KKK N RPVTPPR
Sbjct: 1899 LFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKKKFPYGGLNQGRPVTPPR 1738
>06264
Length = 999
Score = 562 bits (1449), Expect = e-161, Method: Compositional matrix adjust.
Identities = 270/286 (94%), Positives = 277/286 (96%), Gaps = 5/286 (1%)
Frame = -3
Query: 34 EIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDY 93
EIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDY
Sbjct: 997 EIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDY 818
Query: 94 VDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFT 153
VDRG+QSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFT
Sbjct: 817 VDRGRQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFT 638
Query: 154 DCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDV 213
DCFNCLPIAAI+DEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDK+
Sbjct: 637 DCFNCLPIAAIIDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKET 458
Query: 214 LGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYC 273
+GWGE+DRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYC
Sbjct: 457 MGWGESDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYC 278
Query: 274 GEFDNAGAMMSVDETLMCSFQILKPAEKKK-----PNATRPVTPPR 314
GEFDNAGAMMSVDETLMCSFQILKPA+KKK + RPVTPPR
Sbjct: 277 GEFDNAGAMMSVDETLMCSFQILKPADKKKFPYGGLSXGRPVTPPR 140
>19040
Length = 452
Score = 299 bits (766), Expect = 9e-82, Method: Compositional matrix adjust.
Identities = 141/150 (94%), Positives = 145/150 (96%)
Frame = -3
Query: 36 RGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVD 95
RGLCLKSREIFL QPILLELEAPL ICGDIHGQY DLLRLFEYGGFPP +NYLFLGDYVD
Sbjct: 450 RGLCLKSREIFLQQPILLELEAPLIICGDIHGQYTDLLRLFEYGGFPPAANYLFLGDYVD 271
Query: 96 RGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDC 155
RGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYN+KLWKTFTDC
Sbjct: 270 RGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNVKLWKTFTDC 91
Query: 156 FNCLPIAAIVDEKIFCCHGGLSPDLQSMEQ 185
FNCLP+AAI+DEKIFCCHGGLSPDLQ MEQ
Sbjct: 90 FNCLPVAAIIDEKIFCCHGGLSPDLQGMEQ 1
>08242
Length = 3368
Score = 274 bits (700), Expect = 5e-74, Method: Compositional matrix adjust.
Identities = 128/269 (47%), Positives = 189/269 (70%), Gaps = 3/269 (1%)
Frame = -1
Query: 44 EIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLET 103
EI + + + +++P+ +CGDIHGQ+YDL LF+ GG P++NYLF+GD+VDRG S+ET
Sbjct: 3368 EILVEESNVQRVDSPVTVCGDIHGQFYDLKELFKVGGDVPDTNYLFMGDFVDRGFYSVET 3189
Query: 104 ICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRY-NIKLWKTFTDCFNCLPIA 162
LLLA K++YP+ L+RGNHE I ++YGFYDEC R+Y +I +W+ T+ F+ L ++
Sbjct: 3188 FLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLRKYGSITVWRYCTEIFDYLSLS 3009
Query: 163 AIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVLGWGENDRG 222
AI+D KIFC HGGLSP +Q+++QIR I R +VP G +CDLLWSDP+ D+ GWG + RG
Sbjct: 3008 AIIDGKIFCVHGGLSPSIQTLDQIRSIDRKQEVPHDGPMCDLLWSDPE-DMQGWGVSPRG 2832
Query: 223 VSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAM 282
+ FG++VV++F + +DLICRAHQ+V +GY++ ++T++SAPNYC N A+
Sbjct: 2831 AGYLFGSDVVSQFNAANXIDLICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAI 2652
Query: 283 MSVDETLMCSFQILK--PAEKKKPNATRP 309
+ +DE L F I + P E + + +P
Sbjct: 2651 LELDEHLQRDFTIFEAAPQEARGIPSKKP 2565
>06084
Length = 1739
Score = 233 bits (595), Expect = 7e-62, Method: Compositional matrix adjust.
Identities = 121/253 (47%), Positives = 169/253 (66%), Gaps = 1/253 (0%)
Frame = -2
Query: 66 HGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNH 125
HGQ+YDL+ LF+ GG P++NY+F+GD+VDRG SLET LLL K K+P+ LLRGNH
Sbjct: 1738 HGQFYDLMELFKTGGEMPDTNYVFMGDFVDRGYFSLETFTLLLTLKAKWPDKIVLLRGNH 1559
Query: 126 ECASINRIYGFYDECKRRY-NIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSME 184
E I +IYGFYDEC+ +Y N W+ F+ L IAAI+DE I C HGGLSPD+++++
Sbjct: 1558 ESRQITQIYGFYDECQTKYGNANAWRYCCRVFDLLTIAAIIDECILCVHGGLSPDIKTID 1379
Query: 185 QIRRIMRPTDVPDQGLLCDLLWSDPDKDVLGWGENDRGVSFTFGAEVVAKFLHKHDLDLI 244
QIR I R ++P +G CDL+WSDP+ DV W + RG + FGA+V A+F+ ++L LI
Sbjct: 1378 QIRTIERNQEIPHKGAFCDLVWSDPE-DVDTWAMSPRGAGWLFGAKVTAEFVASNNLKLI 1202
Query: 245 CRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPAEKKKP 304
CRAHQ+V +GY++ +LVT++SAPNYC N A++S + ++ K P
Sbjct: 1201 CRAHQLVHEGYKYMFDEKLVTVWSAPNYCYRCGNIAAVLSFTDAEHHEAKLFKAV----P 1034
Query: 305 NATRPVTPPRVAS 317
++ R V PPR +
Sbjct: 1033 DSER-VIPPRTQT 998
>18336
Length = 465
Score = 171 bits (433), Expect(3) = 4e-61, Method: Compositional matrix adjust.
Identities = 86/111 (77%), Positives = 89/111 (80%)
Frame = +2
Query: 26 KNVQLQENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPES 85
KNVQL E + SR I L + + ICGDIHGQYYDLLRLFEYGGFPPES
Sbjct: 2 KNVQLSEQK*EAYV*ISRNI-LESAYSFRIRSTT*ICGDIHGQYYDLLRLFEYGGFPPES 178
Query: 86 NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGF 136
NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGF
Sbjct: 179 NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGF 331
Score = 73.9 bits (180), Expect(3) = 4e-61, Method: Compositional matrix adjust.
Identities = 32/34 (94%), Positives = 33/34 (97%)
Frame = +1
Query: 137 YDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIF 170
YDECKRRYNIKLWKTFTDCFNCLPIAAI+D KIF
Sbjct: 331 YDECKRRYNIKLWKTFTDCFNCLPIAAIIDVKIF 432
Score = 28.9 bits (63), Expect(3) = 4e-61, Method: Compositional matrix adjust.
Identities = 11/12 (91%), Positives = 11/12 (91%)
Frame = +3
Query: 170 FCCHGGLSPDLQ 181
CCHGGLSPDLQ
Sbjct: 429 LCCHGGLSPDLQ 464
>04295
Length = 748
Score = 152 bits (384), Expect = 2e-37, Method: Compositional matrix adjust.
Identities = 72/92 (78%), Positives = 80/92 (86%), Gaps = 6/92 (6%)
Frame = -1
Query: 229 AEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDET 288
+VV+KFL++HDLDLI RAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAG MMSVDET
Sbjct: 748 GDVVSKFLNRHDLDLITRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDET 569
Query: 289 LMCSFQILKPAEKKKP------NATRPVTPPR 314
LMCSFQILKP+EKK N+ RP+TPP+
Sbjct: 568 LMCSFQILKPSEKKAKYQYGGLNSGRPITPPK 473
>25536
Length = 486
Score = 149 bits (376), Expect = 2e-36, Method: Compositional matrix adjust.
Identities = 64/127 (50%), Positives = 94/127 (74%), Gaps = 1/127 (0%)
Frame = +1
Query: 29 QLQENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYL 88
QL EN+++ LC K++EI + + E++ P+ +CGD+HGQ++DL+ LF GG P++NYL
Sbjct: 106 QLSENQVKTLCEKAKEILSKESNVQEVKCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYL 285
Query: 89 FLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRY-NIK 147
F+GDYVDRG S+ET+ LL+A K+++ + +LRGNHE I ++YGFYDEC R+Y N
Sbjct: 286 FMGDYVDRGYYSVETVSLLVALKVRFRDRITILRGNHESRQITQVYGFYDECLRKYGNAN 465
Query: 148 LWKTFTD 154
+WK FTD
Sbjct: 466 VWKYFTD 486
>30980
Length = 765
Score = 67.4 bits (163), Expect = 8e-12, Method: Compositional matrix adjust.
Identities = 34/75 (45%), Positives = 47/75 (62%), Gaps = 1/75 (1%)
Frame = +3
Query: 235 FLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQ 294
F H + L LI RAHQ+V +GY + R +VT+FSAPNYC N A+M +D+ L SF
Sbjct: 6 FNHSNGLTLISRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDALKYSFL 185
Query: 295 ILKPAEKK-KPNATR 308
PA ++ +P+ TR
Sbjct: 186 QFDPAPRRGEPHVTR 230
>21146
Length = 408
Score = 64.3 bits (155), Expect = 8e-11, Method: Compositional matrix adjust.
Identities = 37/78 (47%), Positives = 46/78 (58%), Gaps = 3/78 (3%)
Frame = +3
Query: 198 QGLLCDLLWSDPDKDVLGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQ-VVEDGYE 256
QG +CDLLWSDPD D GWG + RG +TFG ++ F H + L LI RAHQ V+E +
Sbjct: 114 QGPMCDLLWSDPD-DRGGWGISPRGAGYTFGQDISETFNHSNGLTLISRAHQLVMEVMFW 290
Query: 257 FFAKRQLVTLF--SAPNY 272
F Q L+ S NY
Sbjct: 291 FVTGMQTCLLYELSLQNY 344
>36367
Length = 827
Score = 54.7 bits (130), Expect = 6e-08, Method: Compositional matrix adjust.
Identities = 39/132 (29%), Positives = 66/132 (50%), Gaps = 20/132 (15%)
Frame = +1
Query: 173 HGGL-SPDLQS---MEQIRRIMRPTDVP--DQGLLCDLLWSDP-------------DKDV 213
HGG+ SP+ + +E I +I P P D + ++LWSDP K+
Sbjct: 1 HGGIPSPENEGGGHLEAINKIPVPLSDPEVDSPMAWEILWSDPISVDLVSPEVLKDMKEH 180
Query: 214 LGWGENDR-GVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNY 272
G+ N R G + F + FL ++ L + RAH+V E G++ + +L+T+FS+ Y
Sbjct: 181 HGFTFNSRRGTAHFFSCNALLAFLERNGLSHVIRAHEVQEVGFQVQQQGKLLTVFSSSRY 360
Query: 273 CGEFDNAGAMMS 284
CG + A +++
Sbjct: 361 CGGSNEAACVLA 396
>18967
Length = 440
Score = 53.9 bits (128), Expect = 9e-08, Method: Compositional matrix adjust.
Identities = 23/46 (50%), Positives = 34/46 (73%)
Frame = +2
Query: 241 LDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVD 286
LDLICRAHQ+V +G ++ + +LVT++SAPNYC N A++S +
Sbjct: 2 LDLICRAHQLVNEGIKYMFEGKLVTVWSAPNYCYRCGNVAAILSFE 139
>17953
Length = 626
Score = 40.4 bits (93), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 20/56 (35%), Positives = 32/56 (57%), Gaps = 6/56 (10%)
Frame = -2
Query: 236 LHKHDLDLICRAHQVVEDGYEFFAKRQ------LVTLFSAPNYCGEFDNAGAMMSV 285
L +++L I RAH+ + GY + K Q L+T+FSAPNY ++N ++S
Sbjct: 625 LQQNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKVQLLST 458
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000362738 | hsapiens_gene_ensembl | 26S proteasome
non-ATPase regulatory subunit 1 (26S proteasome regulatory subunit
RPN2) (26S proteasome regulatory subunit S1) (26S proteasome subunit
p112). [Source:Uniprot/SWISSPROT;Acc:Q99460]
(922 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
32303 467 e-166
02455 77 4e-14
00896 65 9e-11
34335 47 2e-05
>32303
Length = 1266
Score = 467 bits (1202), Expect(3) = e-166, Method: Compositional matrix adjust.
Identities = 214/261 (81%), Positives = 242/261 (92%)
Frame = -3
Query: 537 QETQHEKILRGLAVGIALVMYGRMEEADALIESLCRDKDPILRRSGMYTVAMAYCGSGNN 596
+ TQHEKILRGLAVGIAL MYGRMEEADAL+ESL RDKDPILR +GMYT+AMAYCGSGNN
Sbjct: 874 RTTQHEKILRGLAVGIALTMYGRMEEADALVESLTRDKDPILRWAGMYTLAMAYCGSGNN 695
Query: 597 KAIRRLLHVAVSDVNDDVRRAAVESLGFILFRTPEQCPSVVSLLSESYNPHVRYGAAMAL 656
+AIRRLLHVAVSDVNDDVRR AV SLGF+LFRTPEQCPSVVSLLSESYNPHVR+GAAMAL
Sbjct: 694 QAIRRLLHVAVSDVNDDVRRVAVTSLGFLLFRTPEQCPSVVSLLSESYNPHVRFGAAMAL 515
Query: 657 GICCAGTGNKEAINLLEPMTNDPVNYVRQGALIASALIMIQQTEITCPKVNQFRQLYSKV 716
GI CAG+G KEA+ LLEPMTNDPVNYVRQGALIASALI+IQ E++CPKV FRQLY+KV
Sbjct: 514 GIACAGSGLKEAMALLEPMTNDPVNYVRQGALIASALILIQHNEVSCPKVTHFRQLYAKV 335
Query: 717 INDKHDDVMAKFGAILAQGILDAGGHNVTISLQSRTGHTHMPSVVGVLVFTQFWFWFPLS 776
I+DKH+DVMAKFGAILAQGI+DAGG N T+SLQSRTGHT+M +VVG+LVF QFW+W+PL+
Sbjct: 334 ISDKHEDVMAKFGAILAQGIIDAGGRNCTVSLQSRTGHTNMDAVVGLLVFCQFWYWYPLT 155
Query: 777 HFLSLAYTPTCVIGLNKDLKV 797
HFLSLA++P C++GLN DLK+
Sbjct: 154 HFLSLAFSPACIVGLNADLKM 92
Score = 101 bits (252), Expect(3) = e-166, Method: Composition-based stats.
Identities = 45/56 (80%), Positives = 49/56 (87%)
Frame = -1
Query: 407 SLGVIHKGHEKEALQLMATYLPKDTSPGSAYQEGGGLYALGLIHANHGGDIIDYLL 462
SLG IH GHEKEAL LM++YLPKDT+ GSAY EGGGLYALGLIHANHGG I +YLL
Sbjct: 1266 SLGCIHHGHEKEALNLMSSYLPKDTTAGSAYSEGGGLYALGLIHANHGGQITEYLL 1099
Score = 59.3 bits (142), Expect(3) = e-166, Method: Compositional matrix adjust.
Identities = 33/85 (38%), Positives = 40/85 (47%)
Frame = -2
Query: 454 GGDIIDYLLNQLKNASNDIVRHXXXXXXXXXXXXXXRQDVYDLLKTNLYQDDXXXXXXXX 513
GG QLK+AS D+VRH RQD+Y+ LK NLYQDD
Sbjct: 1124 GGRSPSTSWGQLKDASTDMVRHGGCLGLGLAAMGTARQDIYEQLKFNLYQDDAVTGEAAG 945
Query: 514 XXXXXXXXXSKNAQAIEDMVGYAQE 538
+K+ AIEDMV YAQ+
Sbjct: 944 LAMGLVMLGTKSTPAIEDMVAYAQD 870
>02455
Length = 832
Score = 76.6 bits (187), Expect = 4e-14, Method: Compositional matrix adjust.
Identities = 28/43 (65%), Positives = 39/43 (90%)
Frame = -1
Query: 755 THMPSVVGVLVFTQFWFWFPLSHFLSLAYTPTCVIGLNKDLKV 797
T+M +VVG+LVF QFW+W+PL+HFLSLA++P C++GLN DLK+
Sbjct: 832 TNMDAVVGLLVFCQFWYWYPLTHFLSLAFSPACIVGLNADLKM 704
Score = 66.6 bits (161), Expect = 5e-11, Method: Compositional matrix adjust.
Identities = 36/61 (59%), Positives = 45/61 (73%), Gaps = 1/61 (1%)
Frame = -1
Query: 844 FQLLDNPARVMPAQLKVLTMPETCRYQPFKPLSIGGIIILKDTS-EDIEELVEPVAAHGP 902
F+LL NPARVM QL+VL+ E RY+P K LS GGI+ILK+ + E+ E+LVE V A GP
Sbjct: 349 FELLSNPARVMKNQLRVLSSSEGSRYRPVKDLSHGGIVILKNVNPEEEEDLVEFVQAGGP 170
Query: 903 K 903
K
Sbjct: 169 K 167
>00896
Length = 2317
Score = 65.5 bits (158), Expect = 9e-11, Method: Compositional matrix adjust.
Identities = 36/61 (59%), Positives = 45/61 (73%), Gaps = 1/61 (1%)
Frame = -3
Query: 844 FQLLDNPARVMPAQLKVLTMPETCRYQPFKPLSIGGIIILKDTS-EDIEELVEPVAAHGP 902
F+LL NPARVM QL+VL+ E RY+P K LS GGI+ILK+ + E+ E+LVE V A GP
Sbjct: 1595 FELLSNPARVMKNQLRVLSSSEGSRYRPVKDLSHGGIVILKNVNPEEEEDLVEFVQAGGP 1416
Query: 903 K 903
K
Sbjct: 1415 K 1413
>34335
Length = 561
Score = 47.4 bits (111), Expect = 2e-05, Method: Composition-based stats.
Identities = 22/26 (84%), Positives = 23/26 (88%)
Frame = +2
Query: 583 MYTVAMAYCGSGNNKAIRRLLHVAVS 608
MYT MAYCGSGNN+AIRRLLHV VS
Sbjct: 23 MYT--MAYCGSGNNQAIRRLLHVVVS 94
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000351298 | hsapiens_gene_ensembl |
Serine/threonine-protein phosphatase PP1-beta catalytic subunit (EC
3.1.3.16) (PP-1B). [Source:Uniprot/SWISSPROT;Acc:P62140]
(367 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
01173 571 e-163
06264 555 e-158
19040 300 8e-82
08242 274 4e-74
06084 225 2e-59
18336 164 1e-58
04295 188 3e-48
25536 144 6e-35
21146 61 7e-10
30980 59 2e-09
36367 57 9e-09
18967 52 3e-07
17953 41 0.001
01222 28 7.2
05700 27 9.7
>01173
Length = 2619
Score = 571 bits (1471), Expect = e-163, Method: Compositional matrix adjust.
Identities = 272/303 (89%), Positives = 288/303 (95%)
Frame = -1
Query: 65 KIVQMTEAEVRGLCIKSREIFLSQPILLELEAPLKICGDIHGQYTDLLRLFEYGGFPPEA 124
K VQ+TE+E+RGLC+KSREIFLSQPILLELEAPLKICGDIHGQY DLLRLFEYGGFPPE+
Sbjct: 2619 KNVQLTESEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPES 2440
Query: 125 NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRFN 184
NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRR+N
Sbjct: 2439 NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYN 2260
Query: 185 IKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDTGLLCDLL 244
IKLWKTFTDCFNCLPIAAI+DEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPD GLLCDLL
Sbjct: 2259 IKLWKTFTDCFNCLPIAAIIDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLL 2080
Query: 245 WSDPDKDVQGWGENDRGVSFTFGADVVSKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVT 304
WSDPDK+ GWGENDRGVSFTFGA+VV+KFL++HDLDLICRAHQVVEDGYEFFAKRQLVT
Sbjct: 2079 WSDPDKETMGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVT 1900
Query: 305 LFSAPNYCGEFDNAGGMMSVDETLMCSFQILKPSEKKAKYQYGGLNSGRPVTPPRTANPP 364
LFSAPNYCGEFDNAG MMSVDETLMCSFQILKP++KK K+ YGGLN GRPVTPPR
Sbjct: 1899 LFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKK-KFPYGGLNQGRPVTPPRGNAKA 1723
Query: 365 KKR 367
K +
Sbjct: 1722 KGK 1714
>06264
Length = 999
Score = 555 bits (1429), Expect = e-158, Method: Compositional matrix adjust.
Identities = 264/295 (89%), Positives = 281/295 (95%)
Frame = -3
Query: 73 EVRGLCIKSREIFLSQPILLELEAPLKICGDIHGQYTDLLRLFEYGGFPPEANYLFLGDY 132
E+RGLC+KSREIFLSQPILLELEAPLKICGDIHGQY DLLRLFEYGGFPPE+NYLFLGDY
Sbjct: 997 EIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDY 818
Query: 133 VDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRFNIKLWKTFT 192
VDRG+QSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRR+NIKLWKTFT
Sbjct: 817 VDRGRQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFT 638
Query: 193 DCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDTGLLCDLLWSDPDKDV 252
DCFNCLPIAAI+DEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPD GLLCDLLWSDPDK+
Sbjct: 637 DCFNCLPIAAIIDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKET 458
Query: 253 QGWGENDRGVSFTFGADVVSKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYC 312
GWGE+DRGVSFTFGA+VV+KFL++HDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYC
Sbjct: 457 MGWGESDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYC 278
Query: 313 GEFDNAGGMMSVDETLMCSFQILKPSEKKAKYQYGGLNSGRPVTPPRTANPPKKR 367
GEFDNAG MMSVDETLMCSFQILKP++KK K+ YGGL+ GRPVTPPR K +
Sbjct: 277 GEFDNAGAMMSVDETLMCSFQILKPADKK-KFPYGGLSXGRPVTPPRGNAKAKGK 116
>19040
Length = 452
Score = 300 bits (767), Expect = 8e-82, Method: Compositional matrix adjust.
Identities = 141/150 (94%), Positives = 146/150 (97%)
Frame = -3
Query: 75 RGLCIKSREIFLSQPILLELEAPLKICGDIHGQYTDLLRLFEYGGFPPEANYLFLGDYVD 134
RGLC+KSREIFL QPILLELEAPL ICGDIHGQYTDLLRLFEYGGFPP ANYLFLGDYVD
Sbjct: 450 RGLCLKSREIFLQQPILLELEAPLIICGDIHGQYTDLLRLFEYGGFPPAANYLFLGDYVD 271
Query: 135 RGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRFNIKLWKTFTDC 194
RGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRR+N+KLWKTFTDC
Sbjct: 270 RGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNVKLWKTFTDC 91
Query: 195 FNCLPIAAIVDEKIFCCHGGLSPDLQSMEQ 224
FNCLP+AAI+DEKIFCCHGGLSPDLQ MEQ
Sbjct: 90 FNCLPVAAIIDEKIFCCHGGLSPDLQGMEQ 1
>08242
Length = 3368
Score = 274 bits (701), Expect = 4e-74, Method: Compositional matrix adjust.
Identities = 129/273 (47%), Positives = 191/273 (69%), Gaps = 1/273 (0%)
Frame = -1
Query: 83 EIFLSQPILLELEAPLKICGDIHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLET 142
EI + + + +++P+ +CGDIHGQ+ DL LF+ GG P+ NYLF+GD+VDRG S+ET
Sbjct: 3368 EILVEESNVQRVDSPVTVCGDIHGQFYDLKELFKVGGDVPDTNYLFMGDFVDRGFYSVET 3189
Query: 143 ICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRF-NIKLWKTFTDCFNCLPIA 201
LLLA K++YP+ L+RGNHE I ++YGFYDEC R++ +I +W+ T+ F+ L ++
Sbjct: 3188 FLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLRKYGSITVWRYCTEIFDYLSLS 3009
Query: 202 AIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDTGLLCDLLWSDPDKDVQGWGENDRG 261
AI+D KIFC HGGLSP +Q+++QIR I R +VP G +CDLLWSDP+ D+QGWG + RG
Sbjct: 3008 AIIDGKIFCVHGGLSPSIQTLDQIRSIDRKQEVPHDGPMCDLLWSDPE-DMQGWGVSPRG 2832
Query: 262 VSFTFGADVVSKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGM 321
+ FG+DVVS+F + +DLICRAHQ+V +GY++ ++T++SAPNYC N +
Sbjct: 2831 AGYLFGSDVVSQFNAANXIDLICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAI 2652
Query: 322 MSVDETLMCSFQILKPSEKKAKYQYGGLNSGRP 354
+ +DE L F I + + ++A+ G+ S +P
Sbjct: 2651 LELDEHLQRDFTIFEAAPQEAR----GIPSKKP 2565
>06084
Length = 1739
Score = 225 bits (574), Expect = 2e-59, Method: Compositional matrix adjust.
Identities = 117/260 (45%), Positives = 162/260 (62%), Gaps = 1/260 (0%)
Frame = -2
Query: 105 HGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNH 164
HGQ+ DL+ LF+ GG P+ NY+F+GD+VDRG SLET LLL K K+P+ LLRGNH
Sbjct: 1738 HGQFYDLMELFKTGGEMPDTNYVFMGDFVDRGYFSLETFTLLLTLKAKWPDKIVLLRGNH 1559
Query: 165 ECASINRIYGFYDECKRRF-NIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSME 223
E I +IYGFYDEC+ ++ N W+ F+ L IAAI+DE I C HGGLSPD+++++
Sbjct: 1558 ESRQITQIYGFYDECQTKYGNANAWRYCCRVFDLLTIAAIIDECILCVHGGLSPDIKTID 1379
Query: 224 QIRRIMRPTDVPDTGLLCDLLWSDPDKDVQGWGENDRGVSFTFGADVVSKFLNRHDLDLI 283
QIR I R ++P G CDL+WSDP+ DV W + RG + FGA V ++F+ ++L LI
Sbjct: 1378 QIRTIERNQEIPHKGAFCDLVWSDPE-DVDTWAMSPRGAGWLFGAKVTAEFVASNNLKLI 1202
Query: 284 CRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQILKPSEKKAK 343
CRAHQ+V +GY++ +LVT++SAPNYC N ++S + +E
Sbjct: 1201 CRAHQLVHEGYKYMFDEKLVTVWSAPNYCYRCGNIAAVLSFTD-----------AEHHEA 1055
Query: 344 YQYGGLNSGRPVTPPRTANP 363
+ + V PPRT P
Sbjct: 1054 KLFKAVPDSERVIPPRTQTP 995
>18336
Length = 465
Score = 164 bits (414), Expect(3) = 1e-58, Method: Compositional matrix adjust.
Identities = 82/111 (73%), Positives = 88/111 (79%)
Frame = +2
Query: 65 KIVQMTEAEVRGLCIKSREIFLSQPILLELEAPLKICGDIHGQYTDLLRLFEYGGFPPEA 124
K VQ++E + SR I L + + ICGDIHGQY DLLRLFEYGGFPPE+
Sbjct: 2 KNVQLSEQK*EAYV*ISRNI-LESAYSFRIRSTT*ICGDIHGQYYDLLRLFEYGGFPPES 178
Query: 125 NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGF 175
NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGF
Sbjct: 179 NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGF 331
Score = 72.8 bits (177), Expect(3) = 1e-58, Method: Compositional matrix adjust.
Identities = 31/34 (91%), Positives = 33/34 (97%)
Frame = +1
Query: 176 YDECKRRFNIKLWKTFTDCFNCLPIAAIVDEKIF 209
YDECKRR+NIKLWKTFTDCFNCLPIAAI+D KIF
Sbjct: 331 YDECKRRYNIKLWKTFTDCFNCLPIAAIIDVKIF 432
Score = 28.9 bits (63), Expect(3) = 1e-58, Method: Compositional matrix adjust.
Identities = 11/12 (91%), Positives = 11/12 (91%)
Frame = +3
Query: 209 FCCHGGLSPDLQ 220
CCHGGLSPDLQ
Sbjct: 429 LCCHGGLSPDLQ 464
>04295
Length = 748
Score = 188 bits (478), Expect = 3e-48, Method: Compositional matrix adjust.
Identities = 88/92 (95%), Positives = 90/92 (97%)
Frame = -1
Query: 268 ADVVSKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDET 327
DVVSKFLNRHDLDLI RAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDET
Sbjct: 748 GDVVSKFLNRHDLDLITRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDET 569
Query: 328 LMCSFQILKPSEKKAKYQYGGLNSGRPVTPPR 359
LMCSFQILKPSEKKAKYQYGGLNSGRP+TPP+
Sbjct: 568 LMCSFQILKPSEKKAKYQYGGLNSGRPITPPK 473
>25536
Length = 486
Score = 144 bits (362), Expect = 6e-35, Method: Compositional matrix adjust.
Identities = 62/127 (48%), Positives = 92/127 (72%), Gaps = 1/127 (0%)
Frame = +1
Query: 68 QMTEAEVRGLCIKSREIFLSQPILLELEAPLKICGDIHGQYTDLLRLFEYGGFPPEANYL 127
Q++E +V+ LC K++EI + + E++ P+ +CGD+HGQ+ DL+ LF GG P+ NYL
Sbjct: 106 QLSENQVKTLCEKAKEILSKESNVQEVKCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYL 285
Query: 128 FLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRF-NIK 186
F+GDYVDRG S+ET+ LL+A K+++ + +LRGNHE I ++YGFYDEC R++ N
Sbjct: 286 FMGDYVDRGYYSVETVSLLVALKVRFRDRITILRGNHESRQITQVYGFYDECLRKYGNAN 465
Query: 187 LWKTFTD 193
+WK FTD
Sbjct: 466 VWKYFTD 486
>21146
Length = 408
Score = 61.2 bits (147), Expect = 7e-10, Method: Compositional matrix adjust.
Identities = 36/77 (46%), Positives = 45/77 (58%), Gaps = 3/77 (3%)
Frame = +3
Query: 238 GLLCDLLWSDPDKDVQGWGENDRGVSFTFGADVVSKFLNRHDLDLICRAHQ-VVEDGYEF 296
G +CDLLWSDPD D GWG + RG +TFG D+ F + + L LI RAHQ V+E + F
Sbjct: 117 GPMCDLLWSDPD-DRGGWGISPRGAGYTFGQDISETFNHSNGLTLISRAHQLVMEVMFWF 293
Query: 297 FAKRQLVTLF--SAPNY 311
Q L+ S NY
Sbjct: 294 VTGMQTCLLYELSLQNY 344
>30980
Length = 765
Score = 59.3 bits (142), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 28/70 (40%), Positives = 42/70 (60%)
Frame = +3
Query: 274 FLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQ 333
F + + L LI RAHQ+V +GY + R +VT+FSAPNYC N +M +D+ L SF
Sbjct: 6 FNHSNGLTLISRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDALKYSFL 185
Query: 334 ILKPSEKKAK 343
P+ ++ +
Sbjct: 186 QFDPAPRRGE 215
>36367
Length = 827
Score = 57.4 bits (137), Expect = 9e-09, Method: Compositional matrix adjust.
Identities = 40/132 (30%), Positives = 68/132 (51%), Gaps = 20/132 (15%)
Frame = +1
Query: 212 HGGL-SPDLQS---MEQIRRIMRPTDVP--DTGLLCDLLWSDPD-------------KDV 252
HGG+ SP+ + +E I +I P P D+ + ++LWSDP K+
Sbjct: 1 HGGIPSPENEGGGHLEAINKIPVPLSDPEVDSPMAWEILWSDPISVDLVSPEVLKDMKEH 180
Query: 253 QGWGENDR-GVSFTFGADVVSKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNY 311
G+ N R G + F + + FL R+ L + RAH+V E G++ + +L+T+FS+ Y
Sbjct: 181 HGFTFNSRRGTAHFFSCNALLAFLERNGLSHVIRAHEVQEVGFQVQQQGKLLTVFSSSRY 360
Query: 312 CGEFDNAGGMMS 323
CG + A +++
Sbjct: 361 CGGSNEAACVLA 396
>18967
Length = 440
Score = 52.4 bits (124), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 22/46 (47%), Positives = 33/46 (71%)
Frame = +2
Query: 280 LDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVD 325
LDLICRAHQ+V +G ++ + +LVT++SAPNYC N ++S +
Sbjct: 2 LDLICRAHQLVNEGIKYMFEGKLVTVWSAPNYCYRCGNVAAILSFE 139
>17953
Length = 626
Score = 40.8 bits (94), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 20/56 (35%), Positives = 32/56 (57%), Gaps = 6/56 (10%)
Frame = -2
Query: 275 LNRHDLDLICRAHQVVEDGYEFFAKRQ------LVTLFSAPNYCGEFDNAGGMMSV 324
L +++L I RAH+ + GY + K Q L+T+FSAPNY ++N ++S
Sbjct: 625 LQQNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKVQLLST 458
>01222
Length = 744
Score = 27.7 bits (60), Expect = 7.2, Method: Compositional matrix adjust.
Identities = 16/55 (29%), Positives = 27/55 (49%), Gaps = 1/55 (1%)
Frame = -2
Query: 158 FLLRGNHECASINRIYGFYDECKRRFNIKLWKTFTDCFNC-LPIAAIVDEKIFCC 211
F + NH C S ++Y + + NIKLW + C + + V+E++F C
Sbjct: 707 FTIHSNHICRSRRKLYTEINPQHVKINIKLWHPTQFFYLCIMYVCRRVNEQVFVC 543
>05700
Length = 913
Score = 27.3 bits (59), Expect = 9.7, Method: Compositional matrix adjust.
Identities = 14/35 (40%), Positives = 19/35 (54%)
Frame = +2
Query: 92 LELEAPLKICGDIHGQYTDLLRLFEYGGFPPEANY 126
L L + + IC IH Y+DL+ F+ FPP Y
Sbjct: 719 LALSSCISIC--IHHNYSDLVLCFQCFSFPPYL*Y 817
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000378769 | hsapiens_gene_ensembl |
Serine/threonine-protein phosphatase PP1-beta catalytic subunit (EC
3.1.3.16) (PP-1B). [Source:Uniprot/SWISSPROT;Acc:P62140]
(327 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
01173 571 e-163
06264 555 e-159
19040 300 6e-82
08242 274 4e-74
06084 225 2e-59
18336 164 2e-58
04295 188 2e-48
25536 144 6e-35
21146 61 6e-10
30980 59 2e-09
36367 57 7e-09
18967 53 2e-07
17953 41 8e-04
01222 28 6.0
05700 27 9.0
>01173
Length = 2619
Score = 571 bits (1471), Expect = e-163, Method: Compositional matrix adjust.
Identities = 271/295 (91%), Positives = 286/295 (96%)
Frame = -1
Query: 25 KIVQMTEAEVRGLCIKSREIFLSQPILLELEAPLKICGDIHGQYTDLLRLFEYGGFPPEA 84
K VQ+TE+E+RGLC+KSREIFLSQPILLELEAPLKICGDIHGQY DLLRLFEYGGFPPE+
Sbjct: 2619 KNVQLTESEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPES 2440
Query: 85 NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRFN 144
NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRR+N
Sbjct: 2439 NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYN 2260
Query: 145 IKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDTGLLCDLL 204
IKLWKTFTDCFNCLPIAAI+DEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPD GLLCDLL
Sbjct: 2259 IKLWKTFTDCFNCLPIAAIIDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLL 2080
Query: 205 WSDPDKDVQGWGENDRGVSFTFGADVVSKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVT 264
WSDPDK+ GWGENDRGVSFTFGA+VV+KFL++HDLDLICRAHQVVEDGYEFFAKRQLVT
Sbjct: 2079 WSDPDKETMGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVT 1900
Query: 265 LFSAPNYCGEFDNAGGMMSVDETLMCSFQILKPSEKKAKYQYGGLNSGRPVTPPR 319
LFSAPNYCGEFDNAG MMSVDETLMCSFQILKP++KK K+ YGGLN GRPVTPPR
Sbjct: 1899 LFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKK-KFPYGGLNQGRPVTPPR 1738
>06264
Length = 999
Score = 555 bits (1431), Expect = e-159, Method: Compositional matrix adjust.
Identities = 264/295 (89%), Positives = 281/295 (95%)
Frame = -3
Query: 33 EVRGLCIKSREIFLSQPILLELEAPLKICGDIHGQYTDLLRLFEYGGFPPEANYLFLGDY 92
E+RGLC+KSREIFLSQPILLELEAPLKICGDIHGQY DLLRLFEYGGFPPE+NYLFLGDY
Sbjct: 997 EIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDY 818
Query: 93 VDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRFNIKLWKTFT 152
VDRG+QSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRR+NIKLWKTFT
Sbjct: 817 VDRGRQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFT 638
Query: 153 DCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDTGLLCDLLWSDPDKDV 212
DCFNCLPIAAI+DEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPD GLLCDLLWSDPDK+
Sbjct: 637 DCFNCLPIAAIIDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKET 458
Query: 213 QGWGENDRGVSFTFGADVVSKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYC 272
GWGE+DRGVSFTFGA+VV+KFL++HDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYC
Sbjct: 457 MGWGESDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYC 278
Query: 273 GEFDNAGGMMSVDETLMCSFQILKPSEKKAKYQYGGLNSGRPVTPPRTANPPKKR 327
GEFDNAG MMSVDETLMCSFQILKP++KK K+ YGGL+ GRPVTPPR K +
Sbjct: 277 GEFDNAGAMMSVDETLMCSFQILKPADKK-KFPYGGLSXGRPVTPPRGNAKAKGK 116
>19040
Length = 452
Score = 300 bits (768), Expect = 6e-82, Method: Compositional matrix adjust.
Identities = 141/150 (94%), Positives = 146/150 (97%)
Frame = -3
Query: 35 RGLCIKSREIFLSQPILLELEAPLKICGDIHGQYTDLLRLFEYGGFPPEANYLFLGDYVD 94
RGLC+KSREIFL QPILLELEAPL ICGDIHGQYTDLLRLFEYGGFPP ANYLFLGDYVD
Sbjct: 450 RGLCLKSREIFLQQPILLELEAPLIICGDIHGQYTDLLRLFEYGGFPPAANYLFLGDYVD 271
Query: 95 RGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRFNIKLWKTFTDC 154
RGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRR+N+KLWKTFTDC
Sbjct: 270 RGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNVKLWKTFTDC 91
Query: 155 FNCLPIAAIVDEKIFCCHGGLSPDLQSMEQ 184
FNCLP+AAI+DEKIFCCHGGLSPDLQ MEQ
Sbjct: 90 FNCLPVAAIIDEKIFCCHGGLSPDLQGMEQ 1
>08242
Length = 3368
Score = 274 bits (700), Expect = 4e-74, Method: Compositional matrix adjust.
Identities = 129/273 (47%), Positives = 191/273 (69%), Gaps = 1/273 (0%)
Frame = -1
Query: 43 EIFLSQPILLELEAPLKICGDIHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLET 102
EI + + + +++P+ +CGDIHGQ+ DL LF+ GG P+ NYLF+GD+VDRG S+ET
Sbjct: 3368 EILVEESNVQRVDSPVTVCGDIHGQFYDLKELFKVGGDVPDTNYLFMGDFVDRGFYSVET 3189
Query: 103 ICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRF-NIKLWKTFTDCFNCLPIA 161
LLLA K++YP+ L+RGNHE I ++YGFYDEC R++ +I +W+ T+ F+ L ++
Sbjct: 3188 FLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLRKYGSITVWRYCTEIFDYLSLS 3009
Query: 162 AIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDTGLLCDLLWSDPDKDVQGWGENDRG 221
AI+D KIFC HGGLSP +Q+++QIR I R +VP G +CDLLWSDP+ D+QGWG + RG
Sbjct: 3008 AIIDGKIFCVHGGLSPSIQTLDQIRSIDRKQEVPHDGPMCDLLWSDPE-DMQGWGVSPRG 2832
Query: 222 VSFTFGADVVSKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGM 281
+ FG+DVVS+F + +DLICRAHQ+V +GY++ ++T++SAPNYC N +
Sbjct: 2831 AGYLFGSDVVSQFNAANXIDLICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAI 2652
Query: 282 MSVDETLMCSFQILKPSEKKAKYQYGGLNSGRP 314
+ +DE L F I + + ++A+ G+ S +P
Sbjct: 2651 LELDEHLQRDFTIFEAAPQEAR----GIPSKKP 2565
>06084
Length = 1739
Score = 225 bits (574), Expect = 2e-59, Method: Compositional matrix adjust.
Identities = 117/260 (45%), Positives = 162/260 (62%), Gaps = 1/260 (0%)
Frame = -2
Query: 65 HGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNH 124
HGQ+ DL+ LF+ GG P+ NY+F+GD+VDRG SLET LLL K K+P+ LLRGNH
Sbjct: 1738 HGQFYDLMELFKTGGEMPDTNYVFMGDFVDRGYFSLETFTLLLTLKAKWPDKIVLLRGNH 1559
Query: 125 ECASINRIYGFYDECKRRF-NIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSME 183
E I +IYGFYDEC+ ++ N W+ F+ L IAAI+DE I C HGGLSPD+++++
Sbjct: 1558 ESRQITQIYGFYDECQTKYGNANAWRYCCRVFDLLTIAAIIDECILCVHGGLSPDIKTID 1379
Query: 184 QIRRIMRPTDVPDTGLLCDLLWSDPDKDVQGWGENDRGVSFTFGADVVSKFLNRHDLDLI 243
QIR I R ++P G CDL+WSDP+ DV W + RG + FGA V ++F+ ++L LI
Sbjct: 1378 QIRTIERNQEIPHKGAFCDLVWSDPE-DVDTWAMSPRGAGWLFGAKVTAEFVASNNLKLI 1202
Query: 244 CRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQILKPSEKKAK 303
CRAHQ+V +GY++ +LVT++SAPNYC N ++S + +E
Sbjct: 1201 CRAHQLVHEGYKYMFDEKLVTVWSAPNYCYRCGNIAAVLSFTD-----------AEHHEA 1055
Query: 304 YQYGGLNSGRPVTPPRTANP 323
+ + V PPRT P
Sbjct: 1054 KLFKAVPDSERVIPPRTQTP 995
>18336
Length = 465
Score = 164 bits (414), Expect(3) = 2e-58, Method: Compositional matrix adjust.
Identities = 82/111 (73%), Positives = 88/111 (79%)
Frame = +2
Query: 25 KIVQMTEAEVRGLCIKSREIFLSQPILLELEAPLKICGDIHGQYTDLLRLFEYGGFPPEA 84
K VQ++E + SR I L + + ICGDIHGQY DLLRLFEYGGFPPE+
Sbjct: 2 KNVQLSEQK*EAYV*ISRNI-LESAYSFRIRSTT*ICGDIHGQYYDLLRLFEYGGFPPES 178
Query: 85 NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGF 135
NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGF
Sbjct: 179 NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGF 331
Score = 72.8 bits (177), Expect(3) = 2e-58, Method: Compositional matrix adjust.
Identities = 31/34 (91%), Positives = 33/34 (97%)
Frame = +1
Query: 136 YDECKRRFNIKLWKTFTDCFNCLPIAAIVDEKIF 169
YDECKRR+NIKLWKTFTDCFNCLPIAAI+D KIF
Sbjct: 331 YDECKRRYNIKLWKTFTDCFNCLPIAAIIDVKIF 432
Score = 28.9 bits (63), Expect(3) = 2e-58, Method: Compositional matrix adjust.
Identities = 11/12 (91%), Positives = 11/12 (91%)
Frame = +3
Query: 169 FCCHGGLSPDLQ 180
CCHGGLSPDLQ
Sbjct: 429 LCCHGGLSPDLQ 464
>04295
Length = 748
Score = 188 bits (478), Expect = 2e-48, Method: Compositional matrix adjust.
Identities = 88/92 (95%), Positives = 90/92 (97%)
Frame = -1
Query: 228 ADVVSKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDET 287
DVVSKFLNRHDLDLI RAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDET
Sbjct: 748 GDVVSKFLNRHDLDLITRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDET 569
Query: 288 LMCSFQILKPSEKKAKYQYGGLNSGRPVTPPR 319
LMCSFQILKPSEKKAKYQYGGLNSGRP+TPP+
Sbjct: 568 LMCSFQILKPSEKKAKYQYGGLNSGRPITPPK 473
>25536
Length = 486
Score = 144 bits (362), Expect = 6e-35, Method: Compositional matrix adjust.
Identities = 62/127 (48%), Positives = 92/127 (72%), Gaps = 1/127 (0%)
Frame = +1
Query: 28 QMTEAEVRGLCIKSREIFLSQPILLELEAPLKICGDIHGQYTDLLRLFEYGGFPPEANYL 87
Q++E +V+ LC K++EI + + E++ P+ +CGD+HGQ+ DL+ LF GG P+ NYL
Sbjct: 106 QLSENQVKTLCEKAKEILSKESNVQEVKCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYL 285
Query: 88 FLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRF-NIK 146
F+GDYVDRG S+ET+ LL+A K+++ + +LRGNHE I ++YGFYDEC R++ N
Sbjct: 286 FMGDYVDRGYYSVETVSLLVALKVRFRDRITILRGNHESRQITQVYGFYDECLRKYGNAN 465
Query: 147 LWKTFTD 153
+WK FTD
Sbjct: 466 VWKYFTD 486
>21146
Length = 408
Score = 60.8 bits (146), Expect = 6e-10, Method: Compositional matrix adjust.
Identities = 36/77 (46%), Positives = 45/77 (58%), Gaps = 3/77 (3%)
Frame = +3
Query: 198 GLLCDLLWSDPDKDVQGWGENDRGVSFTFGADVVSKFLNRHDLDLICRAHQ-VVEDGYEF 256
G +CDLLWSDPD D GWG + RG +TFG D+ F + + L LI RAHQ V+E + F
Sbjct: 117 GPMCDLLWSDPD-DRGGWGISPRGAGYTFGQDISETFNHSNGLTLISRAHQLVMEVMFWF 293
Query: 257 FAKRQLVTLF--SAPNY 271
Q L+ S NY
Sbjct: 294 VTGMQTCLLYELSLQNY 344
>30980
Length = 765
Score = 59.3 bits (142), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 28/70 (40%), Positives = 42/70 (60%)
Frame = +3
Query: 234 FLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQ 293
F + + L LI RAHQ+V +GY + R +VT+FSAPNYC N +M +D+ L SF
Sbjct: 6 FNHSNGLTLISRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDALKYSFL 185
Query: 294 ILKPSEKKAK 303
P+ ++ +
Sbjct: 186 QFDPAPRRGE 215
>36367
Length = 827
Score = 57.4 bits (137), Expect = 7e-09, Method: Compositional matrix adjust.
Identities = 40/132 (30%), Positives = 68/132 (51%), Gaps = 20/132 (15%)
Frame = +1
Query: 172 HGGL-SPDLQS---MEQIRRIMRPTDVP--DTGLLCDLLWSDPD-------------KDV 212
HGG+ SP+ + +E I +I P P D+ + ++LWSDP K+
Sbjct: 1 HGGIPSPENEGGGHLEAINKIPVPLSDPEVDSPMAWEILWSDPISVDLVSPEVLKDMKEH 180
Query: 213 QGWGENDR-GVSFTFGADVVSKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNY 271
G+ N R G + F + + FL R+ L + RAH+V E G++ + +L+T+FS+ Y
Sbjct: 181 HGFTFNSRRGTAHFFSCNALLAFLERNGLSHVIRAHEVQEVGFQVQQQGKLLTVFSSSRY 360
Query: 272 CGEFDNAGGMMS 283
CG + A +++
Sbjct: 361 CGGSNEAACVLA 396
>18967
Length = 440
Score = 52.8 bits (125), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 22/46 (47%), Positives = 33/46 (71%)
Frame = +2
Query: 240 LDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVD 285
LDLICRAHQ+V +G ++ + +LVT++SAPNYC N ++S +
Sbjct: 2 LDLICRAHQLVNEGIKYMFEGKLVTVWSAPNYCYRCGNVAAILSFE 139
>17953
Length = 626
Score = 40.8 bits (94), Expect = 8e-04, Method: Compositional matrix adjust.
Identities = 20/56 (35%), Positives = 32/56 (57%), Gaps = 6/56 (10%)
Frame = -2
Query: 235 LNRHDLDLICRAHQVVEDGYEFFAKRQ------LVTLFSAPNYCGEFDNAGGMMSV 284
L +++L I RAH+ + GY + K Q L+T+FSAPNY ++N ++S
Sbjct: 625 LQQNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKVQLLST 458
>01222
Length = 744
Score = 27.7 bits (60), Expect = 6.0, Method: Compositional matrix adjust.
Identities = 16/55 (29%), Positives = 27/55 (49%), Gaps = 1/55 (1%)
Frame = -2
Query: 118 FLLRGNHECASINRIYGFYDECKRRFNIKLWKTFTDCFNCLP-IAAIVDEKIFCC 171
F + NH C S ++Y + + NIKLW + C+ + V+E++F C
Sbjct: 707 FTIHSNHICRSRRKLYTEINPQHVKINIKLWHPTQFFYLCIMYVCRRVNEQVFVC 543
>05700
Length = 913
Score = 27.3 bits (59), Expect = 9.0, Method: Compositional matrix adjust.
Identities = 14/35 (40%), Positives = 19/35 (54%)
Frame = +2
Query: 52 LELEAPLKICGDIHGQYTDLLRLFEYGGFPPEANY 86
L L + + IC IH Y+DL+ F+ FPP Y
Sbjct: 719 LALSSCISIC--IHHNYSDLVLCFQCFSFPPYL*Y 817
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000378770 | hsapiens_gene_ensembl |
Serine/threonine-protein phosphatase PP1-beta catalytic subunit (EC
3.1.3.16) (PP-1B). [Source:Uniprot/SWISSPROT;Acc:P62140]
(356 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
01173 570 e-163
06264 555 e-158
19040 300 7e-82
08242 274 3e-74
06084 225 2e-59
18336 164 2e-58
04295 188 3e-48
25536 144 7e-35
21146 61 6e-10
30980 59 2e-09
36367 57 9e-09
18967 53 2e-07
17953 41 0.001
01222 28 6.7
05700 27 9.8
>01173
Length = 2619
Score = 570 bits (1469), Expect = e-163, Method: Compositional matrix adjust.
Identities = 272/303 (89%), Positives = 288/303 (95%)
Frame = -1
Query: 54 KIVQMTEAEVRGLCIKSREIFLSQPILLELEAPLKICGDIHGQYTDLLRLFEYGGFPPEA 113
K VQ+TE+E+RGLC+KSREIFLSQPILLELEAPLKICGDIHGQY DLLRLFEYGGFPPE+
Sbjct: 2619 KNVQLTESEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPES 2440
Query: 114 NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRFN 173
NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRR+N
Sbjct: 2439 NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYN 2260
Query: 174 IKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDTGLLCDLL 233
IKLWKTFTDCFNCLPIAAI+DEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPD GLLCDLL
Sbjct: 2259 IKLWKTFTDCFNCLPIAAIIDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLL 2080
Query: 234 WSDPDKDVQGWGENDRGVSFTFGADVVSKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVT 293
WSDPDK+ GWGENDRGVSFTFGA+VV+KFL++HDLDLICRAHQVVEDGYEFFAKRQLVT
Sbjct: 2079 WSDPDKETMGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVT 1900
Query: 294 LFSAPNYCGEFDNAGGMMSVDETLMCSFQILKPSEKKAKYQYGGLNSGRPVTPPRTANPP 353
LFSAPNYCGEFDNAG MMSVDETLMCSFQILKP++KK K+ YGGLN GRPVTPPR
Sbjct: 1899 LFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKK-KFPYGGLNQGRPVTPPRGNAKA 1723
Query: 354 KKR 356
K +
Sbjct: 1722 KGK 1714
>06264
Length = 999
Score = 555 bits (1429), Expect = e-158, Method: Compositional matrix adjust.
Identities = 264/295 (89%), Positives = 281/295 (95%)
Frame = -3
Query: 62 EVRGLCIKSREIFLSQPILLELEAPLKICGDIHGQYTDLLRLFEYGGFPPEANYLFLGDY 121
E+RGLC+KSREIFLSQPILLELEAPLKICGDIHGQY DLLRLFEYGGFPPE+NYLFLGDY
Sbjct: 997 EIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDY 818
Query: 122 VDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRFNIKLWKTFT 181
VDRG+QSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRR+NIKLWKTFT
Sbjct: 817 VDRGRQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFT 638
Query: 182 DCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDTGLLCDLLWSDPDKDV 241
DCFNCLPIAAI+DEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPD GLLCDLLWSDPDK+
Sbjct: 637 DCFNCLPIAAIIDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKET 458
Query: 242 QGWGENDRGVSFTFGADVVSKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYC 301
GWGE+DRGVSFTFGA+VV+KFL++HDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYC
Sbjct: 457 MGWGESDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYC 278
Query: 302 GEFDNAGGMMSVDETLMCSFQILKPSEKKAKYQYGGLNSGRPVTPPRTANPPKKR 356
GEFDNAG MMSVDETLMCSFQILKP++KK K+ YGGL+ GRPVTPPR K +
Sbjct: 277 GEFDNAGAMMSVDETLMCSFQILKPADKK-KFPYGGLSXGRPVTPPRGNAKAKGK 116
>19040
Length = 452
Score = 300 bits (768), Expect = 7e-82, Method: Compositional matrix adjust.
Identities = 141/150 (94%), Positives = 146/150 (97%)
Frame = -3
Query: 64 RGLCIKSREIFLSQPILLELEAPLKICGDIHGQYTDLLRLFEYGGFPPEANYLFLGDYVD 123
RGLC+KSREIFL QPILLELEAPL ICGDIHGQYTDLLRLFEYGGFPP ANYLFLGDYVD
Sbjct: 450 RGLCLKSREIFLQQPILLELEAPLIICGDIHGQYTDLLRLFEYGGFPPAANYLFLGDYVD 271
Query: 124 RGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRFNIKLWKTFTDC 183
RGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRR+N+KLWKTFTDC
Sbjct: 270 RGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNVKLWKTFTDC 91
Query: 184 FNCLPIAAIVDEKIFCCHGGLSPDLQSMEQ 213
FNCLP+AAI+DEKIFCCHGGLSPDLQ MEQ
Sbjct: 90 FNCLPVAAIIDEKIFCCHGGLSPDLQGMEQ 1
>08242
Length = 3368
Score = 274 bits (701), Expect = 3e-74, Method: Compositional matrix adjust.
Identities = 129/273 (47%), Positives = 191/273 (69%), Gaps = 1/273 (0%)
Frame = -1
Query: 72 EIFLSQPILLELEAPLKICGDIHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLET 131
EI + + + +++P+ +CGDIHGQ+ DL LF+ GG P+ NYLF+GD+VDRG S+ET
Sbjct: 3368 EILVEESNVQRVDSPVTVCGDIHGQFYDLKELFKVGGDVPDTNYLFMGDFVDRGFYSVET 3189
Query: 132 ICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRF-NIKLWKTFTDCFNCLPIA 190
LLLA K++YP+ L+RGNHE I ++YGFYDEC R++ +I +W+ T+ F+ L ++
Sbjct: 3188 FLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLRKYGSITVWRYCTEIFDYLSLS 3009
Query: 191 AIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDTGLLCDLLWSDPDKDVQGWGENDRG 250
AI+D KIFC HGGLSP +Q+++QIR I R +VP G +CDLLWSDP+ D+QGWG + RG
Sbjct: 3008 AIIDGKIFCVHGGLSPSIQTLDQIRSIDRKQEVPHDGPMCDLLWSDPE-DMQGWGVSPRG 2832
Query: 251 VSFTFGADVVSKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGM 310
+ FG+DVVS+F + +DLICRAHQ+V +GY++ ++T++SAPNYC N +
Sbjct: 2831 AGYLFGSDVVSQFNAANXIDLICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAI 2652
Query: 311 MSVDETLMCSFQILKPSEKKAKYQYGGLNSGRP 343
+ +DE L F I + + ++A+ G+ S +P
Sbjct: 2651 LELDEHLQRDFTIFEAAPQEAR----GIPSKKP 2565
>06084
Length = 1739
Score = 225 bits (574), Expect = 2e-59, Method: Compositional matrix adjust.
Identities = 117/260 (45%), Positives = 162/260 (62%), Gaps = 1/260 (0%)
Frame = -2
Query: 94 HGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNH 153
HGQ+ DL+ LF+ GG P+ NY+F+GD+VDRG SLET LLL K K+P+ LLRGNH
Sbjct: 1738 HGQFYDLMELFKTGGEMPDTNYVFMGDFVDRGYFSLETFTLLLTLKAKWPDKIVLLRGNH 1559
Query: 154 ECASINRIYGFYDECKRRF-NIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSME 212
E I +IYGFYDEC+ ++ N W+ F+ L IAAI+DE I C HGGLSPD+++++
Sbjct: 1558 ESRQITQIYGFYDECQTKYGNANAWRYCCRVFDLLTIAAIIDECILCVHGGLSPDIKTID 1379
Query: 213 QIRRIMRPTDVPDTGLLCDLLWSDPDKDVQGWGENDRGVSFTFGADVVSKFLNRHDLDLI 272
QIR I R ++P G CDL+WSDP+ DV W + RG + FGA V ++F+ ++L LI
Sbjct: 1378 QIRTIERNQEIPHKGAFCDLVWSDPE-DVDTWAMSPRGAGWLFGAKVTAEFVASNNLKLI 1202
Query: 273 CRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQILKPSEKKAK 332
CRAHQ+V +GY++ +LVT++SAPNYC N ++S + +E
Sbjct: 1201 CRAHQLVHEGYKYMFDEKLVTVWSAPNYCYRCGNIAAVLSFTD-----------AEHHEA 1055
Query: 333 YQYGGLNSGRPVTPPRTANP 352
+ + V PPRT P
Sbjct: 1054 KLFKAVPDSERVIPPRTQTP 995
>18336
Length = 465
Score = 164 bits (414), Expect(3) = 2e-58, Method: Compositional matrix adjust.
Identities = 82/111 (73%), Positives = 88/111 (79%)
Frame = +2
Query: 54 KIVQMTEAEVRGLCIKSREIFLSQPILLELEAPLKICGDIHGQYTDLLRLFEYGGFPPEA 113
K VQ++E + SR I L + + ICGDIHGQY DLLRLFEYGGFPPE+
Sbjct: 2 KNVQLSEQK*EAYV*ISRNI-LESAYSFRIRSTT*ICGDIHGQYYDLLRLFEYGGFPPES 178
Query: 114 NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGF 164
NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGF
Sbjct: 179 NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGF 331
Score = 72.8 bits (177), Expect(3) = 2e-58, Method: Compositional matrix adjust.
Identities = 31/34 (91%), Positives = 33/34 (97%)
Frame = +1
Query: 165 YDECKRRFNIKLWKTFTDCFNCLPIAAIVDEKIF 198
YDECKRR+NIKLWKTFTDCFNCLPIAAI+D KIF
Sbjct: 331 YDECKRRYNIKLWKTFTDCFNCLPIAAIIDVKIF 432
Score = 28.9 bits (63), Expect(3) = 2e-58, Method: Compositional matrix adjust.
Identities = 11/12 (91%), Positives = 11/12 (91%)
Frame = +3
Query: 198 FCCHGGLSPDLQ 209
CCHGGLSPDLQ
Sbjct: 429 LCCHGGLSPDLQ 464
>04295
Length = 748
Score = 188 bits (478), Expect = 3e-48, Method: Compositional matrix adjust.
Identities = 88/92 (95%), Positives = 90/92 (97%)
Frame = -1
Query: 257 ADVVSKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDET 316
DVVSKFLNRHDLDLI RAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDET
Sbjct: 748 GDVVSKFLNRHDLDLITRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDET 569
Query: 317 LMCSFQILKPSEKKAKYQYGGLNSGRPVTPPR 348
LMCSFQILKPSEKKAKYQYGGLNSGRP+TPP+
Sbjct: 568 LMCSFQILKPSEKKAKYQYGGLNSGRPITPPK 473
>25536
Length = 486
Score = 144 bits (362), Expect = 7e-35, Method: Compositional matrix adjust.
Identities = 62/127 (48%), Positives = 92/127 (72%), Gaps = 1/127 (0%)
Frame = +1
Query: 57 QMTEAEVRGLCIKSREIFLSQPILLELEAPLKICGDIHGQYTDLLRLFEYGGFPPEANYL 116
Q++E +V+ LC K++EI + + E++ P+ +CGD+HGQ+ DL+ LF GG P+ NYL
Sbjct: 106 QLSENQVKTLCEKAKEILSKESNVQEVKCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYL 285
Query: 117 FLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRF-NIK 175
F+GDYVDRG S+ET+ LL+A K+++ + +LRGNHE I ++YGFYDEC R++ N
Sbjct: 286 FMGDYVDRGYYSVETVSLLVALKVRFRDRITILRGNHESRQITQVYGFYDECLRKYGNAN 465
Query: 176 LWKTFTD 182
+WK FTD
Sbjct: 466 VWKYFTD 486
>21146
Length = 408
Score = 61.2 bits (147), Expect = 6e-10, Method: Compositional matrix adjust.
Identities = 36/77 (46%), Positives = 45/77 (58%), Gaps = 3/77 (3%)
Frame = +3
Query: 227 GLLCDLLWSDPDKDVQGWGENDRGVSFTFGADVVSKFLNRHDLDLICRAHQ-VVEDGYEF 285
G +CDLLWSDPD D GWG + RG +TFG D+ F + + L LI RAHQ V+E + F
Sbjct: 117 GPMCDLLWSDPD-DRGGWGISPRGAGYTFGQDISETFNHSNGLTLISRAHQLVMEVMFWF 293
Query: 286 FAKRQLVTLF--SAPNY 300
Q L+ S NY
Sbjct: 294 VTGMQTCLLYELSLQNY 344
>30980
Length = 765
Score = 59.3 bits (142), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 28/70 (40%), Positives = 42/70 (60%)
Frame = +3
Query: 263 FLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQ 322
F + + L LI RAHQ+V +GY + R +VT+FSAPNYC N +M +D+ L SF
Sbjct: 6 FNHSNGLTLISRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDALKYSFL 185
Query: 323 ILKPSEKKAK 332
P+ ++ +
Sbjct: 186 QFDPAPRRGE 215
>36367
Length = 827
Score = 57.4 bits (137), Expect = 9e-09, Method: Compositional matrix adjust.
Identities = 40/132 (30%), Positives = 68/132 (51%), Gaps = 20/132 (15%)
Frame = +1
Query: 201 HGGL-SPDLQS---MEQIRRIMRPTDVP--DTGLLCDLLWSDPD-------------KDV 241
HGG+ SP+ + +E I +I P P D+ + ++LWSDP K+
Sbjct: 1 HGGIPSPENEGGGHLEAINKIPVPLSDPEVDSPMAWEILWSDPISVDLVSPEVLKDMKEH 180
Query: 242 QGWGENDR-GVSFTFGADVVSKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNY 300
G+ N R G + F + + FL R+ L + RAH+V E G++ + +L+T+FS+ Y
Sbjct: 181 HGFTFNSRRGTAHFFSCNALLAFLERNGLSHVIRAHEVQEVGFQVQQQGKLLTVFSSSRY 360
Query: 301 CGEFDNAGGMMS 312
CG + A +++
Sbjct: 361 CGGSNEAACVLA 396
>18967
Length = 440
Score = 52.8 bits (125), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 22/46 (47%), Positives = 33/46 (71%)
Frame = +2
Query: 269 LDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVD 314
LDLICRAHQ+V +G ++ + +LVT++SAPNYC N ++S +
Sbjct: 2 LDLICRAHQLVNEGIKYMFEGKLVTVWSAPNYCYRCGNVAAILSFE 139
>17953
Length = 626
Score = 40.8 bits (94), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 20/56 (35%), Positives = 32/56 (57%), Gaps = 6/56 (10%)
Frame = -2
Query: 264 LNRHDLDLICRAHQVVEDGYEFFAKRQ------LVTLFSAPNYCGEFDNAGGMMSV 313
L +++L I RAH+ + GY + K Q L+T+FSAPNY ++N ++S
Sbjct: 625 LQQNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKVQLLST 458
>01222
Length = 744
Score = 27.7 bits (60), Expect = 6.7, Method: Compositional matrix adjust.
Identities = 16/55 (29%), Positives = 27/55 (49%), Gaps = 1/55 (1%)
Frame = -2
Query: 147 FLLRGNHECASINRIYGFYDECKRRFNIKLWKTFTDCFNCLP-IAAIVDEKIFCC 200
F + NH C S ++Y + + NIKLW + C+ + V+E++F C
Sbjct: 707 FTIHSNHICRSRRKLYTEINPQHVKINIKLWHPTQFFYLCIMYVCRRVNEQVFVC 543
>05700
Length = 913
Score = 27.3 bits (59), Expect = 9.8, Method: Compositional matrix adjust.
Identities = 14/35 (40%), Positives = 19/35 (54%)
Frame = +2
Query: 81 LELEAPLKICGDIHGQYTDLLRLFEYGGFPPEANY 115
L L + + IC IH Y+DL+ F+ FPP Y
Sbjct: 719 LALSSCISIC--IHHNYSDLVLCFQCFSFPPYL*Y 817
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000250416 | hsapiens_gene_ensembl | Poly
[ADP-ribose] polymerase 2 (EC 2.4.2.30) (PARP-2) (NAD(+) ADP-
ribosyltransferase 2) (Poly[ADP-ribose] synthetase 2) (pADPRT-2)
(hPARP-2). [Source:Uniprot/SWISSPROT;Acc:Q9UGN5]
(583 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
06293 389 e-158
07234 207 1e-53
04480 125 5e-29
10167 92 8e-23
32072 72 8e-13
11193 50 3e-06
>06293
Length = 2053
Score = 389 bits (1000), Expect(2) = e-158, Method: Compositional matrix adjust.
Identities = 205/388 (52%), Positives = 269/388 (69%)
Frame = +2
Query: 55 GKANKDRTEDKQDGMPGRSWASKRVSESVKALLLKGKAPVDPECTAKVGKAHVYCEGNDV 114
G + + R E K+ G S +K V V ++ KG APVD EC GK VY + +
Sbjct: 32 GSSGQSRAESKKREENG-SGDTKSVVRQV--VVNKGSAPVDAECPL-AGKCRVYEAASTI 199
Query: 115 YDVMLNQTNLQFNNNKYYLIQLLEDDAQRNFSVWMRWGRVGKMGQHSLVACSGNLNKAKE 174
+D MLNQTN+ NNNKYY+IQ+LED +++ + VW RWGRVG GQ +LV G+LNKA +
Sbjct: 200 WDCMLNQTNVGNNNNKYYIIQVLEDTSKKAYHVWQRWGRVGYKGQTNLVNTGGDLNKAID 379
Query: 175 IFQKKFLDKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDXXXXXXXXXXXXXXXXXXQL 234
+F KKF DKTKN+W +R F KVPGKYD++ +DY+ +D +L
Sbjct: 380 VFSKKFQDKTKNHWNNRNNFLKVPGKYDLVHLDYSAKEEDQVDAGEAGDNEDSQAPDSKL 559
Query: 235 DLRVQELIKLICNVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQH 294
+VQ+L+K+IC+V++MEE ++EMKY+ KKAPLGKLT QI AGY+SLK+IE I
Sbjct: 560 HQKVQDLVKMICDVKSMEEAVVEMKYDAKKAPLGKLTKDQITAGYESLKEIESLINTKDF 739
Query: 295 GRALMEACNEFYTRIPHDFGLRTPPLIRTQKELSEKIQLLEALGDIEIAIKLVKTELQSP 354
GR L +AC+EFYTRIPHDFG+RTPP+IRT KE+ EK+QLLEAL DI+ AIK++K +S
Sbjct: 740 GRNLTDACSEFYTRIPHDFGMRTPPVIRTPKEVKEKLQLLEALEDIQYAIKMLKQGDKS- 916
Query: 355 EHPLDQHYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEKDGEKE 414
E+P+D+HY +L CAL PLDH S +FK+I YL THA TH+ Y M LL+L++V+K GEKE
Sbjct: 917 ENPVDRHYHSLACALSPLDHGSDDFKLIESYLLETHAATHNQYKMKLLELYDVDKQGEKE 1096
Query: 415 AFREDLHNRMLLWHGSRMSNWVGILSHG 442
+ D NRMLLWHGSR++NW GIL G
Sbjct: 1097RYL-DYGNRMLLWHGSRLTNWAGILGQG 1177
Score = 189 bits (479), Expect(2) = e-158, Method: Compositional matrix adjust.
Identities = 90/144 (62%), Positives = 110/144 (76%), Gaps = 1/144 (0%)
Frame = +1
Query: 437 GILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSANYCFASRLKNTGLLLLSEVALGQCN 496
G GLRIAPPEAP+TGYMFGKG+YFADMSSKSANYCFAS+ KN G++LL +V+LG N
Sbjct: 1159 GYPGSGLRIAPPEAPVTGYMFGKGVYFADMSSKSANYCFASKQKNVGMMLLCDVSLGNIN 1338
Query: 497 ELLEANPKAEGLLQGKHSTKGLGKMAPSSAHFVT-LNGSTVPLGPASDTGILNPDGYTLN 555
E L+A+ A+ L GKHS KG G + P + F T +G VP+G ++TG+ NP GYTLN
Sbjct: 1339 EKLDADYYADKLPSGKHSVKGCGSVGPDPSTFKTQPDGLVVPVGKGTNTGVTNPKGYTLN 1518
Query: 556 YNEYIVYNPNQVRMRYLLKVQFNF 579
YNE+IVYN Q+RM+YLLKVQF F
Sbjct: 1519 YNEFIVYNTAQIRMKYLLKVQFKF 1590
>07234
Length = 543
Score = 207 bits (527), Expect = 1e-53, Method: Compositional matrix adjust.
Identities = 98/171 (57%), Positives = 126/171 (73%), Gaps = 2/171 (1%)
Frame = -2
Query: 355 EHPLDQHYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEKDGEKE 414
E P+D HY+ L C + PLD++ FK + +Y+Q+THA TH YT+ +LD+FE++++GE +
Sbjct: 512 EDPIDAHYKKLKCTMEPLDNKGDMFKRLCEYVQNTHAATHQQYTLDVLDIFEMDREGETQ 333
Query: 415 AFR--EDLHNRMLLWHGSRMSNWVGILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSAN 472
F + LHNR LLWHGSR +N+ GILS GLRIAPPEAP+TGYMFGKGIYFADM SKSAN
Sbjct: 332 QFEPFKALHNRQLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSAN 153
Query: 473 YCFASRLKNTGLLLLSEVALGQCNELLEANPKAEGLLQGKHSTKGLGKMAP 523
YC S+ G+LLL EVALG +EL A+ L +GKHSTKG+G+ P
Sbjct: 152 YCRTSKADPIGILLLCEVALGNMHELTSAS-YVTKLPKGKHSTKGIGRTTP 3
>04480
Length = 1878
Score = 125 bits (313), Expect = 5e-29, Method: Compositional matrix adjust.
Identities = 81/219 (36%), Positives = 125/219 (57%), Gaps = 4/219 (1%)
Frame = -3
Query: 359 DQHYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEKDGEKEAFRE 418
D YR++ ++PL +E + + Y+ + S + + +++V + GE EA ++
Sbjct: 1828 DYIYRSMGSKIQPLSENEHETQYLLTYINA------SGHGCKVNAVYKVSRPGEVEALKD 1667
Query: 419 -DLHNRMLLWHGSRMSNWVGILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSANYCFAS 477
LHN LLWHG+ M+N V ILS GL +AP AP G FG+G+YFAD +KS +YC+ +
Sbjct: 1666 VGLHNHRLLWHGTSMANIVSILSRGLLVAPANAPRNGNAFGEGVYFADCFTKSRSYCY-N 1490
Query: 478 RLKNTGLLLLSEVALGQCNELLEANPKAEGLLQGKHSTKGLGKMAPSSAHFVTL-NGSTV 536
+ + ++LL +VALG E L + + + + HS K LG M P + L G+T+
Sbjct: 1489 AVGSCKVMLLCQVALGNSLEDL-CHDEEDHHDEDVHSLKVLGCMQPDPDFDIVLPYGATL 1313
Query: 537 PLGPASDTGILNPDGYT--LNYNEYIVYNPNQVRMRYLL 573
PLG + DG T L YNEYIV+NP Q+ +RY++
Sbjct: 1312 PLGQLKK---MTYDGKTPSLQYNEYIVHNPQQICIRYII 1205
>10167
Length = 959
Score = 77.0 bits (188), Expect(3) = 8e-23, Method: Compositional matrix adjust.
Identities = 62/213 (29%), Positives = 106/213 (49%), Gaps = 12/213 (5%)
Frame = -1
Query: 251 MEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGRALMEACNEFYTRIP 310
M++ MME + + KK PLGKL+ QI++ Y+ L +++D + ++A N FYT IP
Sbjct: 611 MKKAMMEFEIDMKKMPLGKLSKRQIESAYKVLTELQDLVTKKGTQTQFVDATNRFYTLIP 432
Query: 311 HDFGLRTPPLIRTQKELSEKIQLLEALGDIEIAIKLVKTELQSPEHPLDQHYRNLHCALR 370
HDFG+ L+ T++ + K ++L+ L +IE+A L++ D+ R +L+
Sbjct: 431 HDFGMGKIKLLDTEEAIKSKTEMLDNLLEIEVAYSLLRGG--------DKRRRPHRRSLQ 276
Query: 371 PLDHESYEFKVISQYLQST------HAPTHSDYTMTLLDLF----EVEKDGEKEAFREDL 420
F +++Q+T H+ H+ T + D +
Sbjct: 275 ETQVYHGAFGQ*RRHVQATV*ICTEHSRCHTSTVHTGRSGYL*NGS*GGDTAV*TIQGSA 96
Query: 421 HNRMLLWHGSRMSN--WVGILSHGLRIAPPEAP 451
+ +++ +R+S+ GILS GLRIAPPEAP
Sbjct: 95 QSSVVV---ARVSDHQLAGILSQGLRIAPPEAP 6
Score = 40.0 bits (92), Expect(3) = 8e-23, Method: Compositional matrix adjust.
Identities = 30/102 (29%), Positives = 45/102 (44%)
Frame = -3
Query: 152 GRVGKMGQHSLVACSGNLNKAKEIFQKKFLDKTKNNWEDREKFEKVPGKYDMLQMDYATN 211
G G G + V G+ + F++ +L KT N+WE R+ F+K P K+ L +DY
Sbjct: 888 GSCGHDGGGNKVERCGSKASVIDKFRELYLSKTGNDWEQRKHFKKQPNKFYPLDIDYGQE 709
Query: 212 TQDXXXXXXXXXXXXXXXXXXQLDLRVQELIKLICNVQAMEE 253
+ +L VQ+LI LI +V EE
Sbjct: 708 DE-------TIQKLTVSDSNSKLAKSVQDLICLIFDVGPDEE 604
Score = 28.5 bits (62), Expect(3) = 8e-23, Method: Compositional matrix adjust.
Identities = 11/27 (40%), Positives = 18/27 (66%)
Frame = -1
Query: 129 NKYYLIQLLEDDAQRNFSVWMRWGRVG 155
N +Y +Q LE D+ ++ ++ WGRVG
Sbjct: 956 NSFYKLQALEGDSANSYWLYRAWGRVG 876
Score = 92.0 bits (227), Expect = 6e-19, Method: Compositional matrix adjust.
Identities = 40/82 (48%), Positives = 59/82 (71%), Gaps = 2/82 (2%)
Frame = -2
Query: 355 EHPLDQHYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEKDGEKE 414
E P+D HY+ L C + PLD++ FK + +Y+Q+THA TH YT+ +LD+FE++++GE +
Sbjct: 301 EDPIDAHYKKLKCTMEPLDNKGDMFKRLCEYVQNTHAATHQQYTLDVLDIFEMDREGETQ 122
Query: 415 AFR--EDLHNRMLLWHGSRMSN 434
F + LHNR LLWHGSR +N
Sbjct: 121 QFEPFKALHNRQLLWHGSRTTN 56
>32072
Length = 272
Score = 71.6 bits (174), Expect = 8e-13, Method: Composition-based stats.
Identities = 39/68 (57%), Positives = 52/68 (76%)
Frame = +1
Query: 114 VYDVMLNQTNLQFNNNKYYLIQLLEDDAQRNFSVWMRWGRVGKMGQHSLVACSGNLNKAK 173
++D MLNQTN+ NNNKYY+IQ+LED +++ + VW RWGRVG GQ +LV G+LNKA
Sbjct: 7 IWDCMLNQTNVGNNNNKYYIIQVLEDTSKKAYHVWQRWGRVGYKGQTNLVNTGGDLNKAI 186
Query: 174 EIFQKKFL 181
++F KK L
Sbjct: 187 DVFSKKSL 210
>11193
Length = 1001
Score = 49.7 bits (117), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 35/120 (29%), Positives = 57/120 (47%), Gaps = 5/120 (4%)
Frame = -2
Query: 90 GKAP-VDPECTAK-VGKAHVYCEGNDVYDVMLNQTNLQ---FNNNKYYLIQLLEDDAQRN 144
+AP VD C + G+ + N YD+ L + ++ + +Y IQ++ A+
Sbjct: 781 ARAPKVDSNCEMRATGELYHDETKNKTYDITLTKVDVSTGTWGMYNFYKIQIVRQKAKDM 602
Query: 145 FSVWMRWGRVGKMGQHSLVACSGNLNKAKEIFQKKFLDKTKNNWEDREKFEKVPGKYDML 204
+ ++ RWGR+G GQ + KE F K F KT N+W EKF + KY ++
Sbjct: 601 YVLFTRWGRIGDRGQWQHTPFPTAEDAIKE-FCKVFRQKTGNDWNHLEKFVEHKKKYRLM 425
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000279387 | hsapiens_gene_ensembl |
Serine/threonine-protein phosphatase 4 catalytic subunit (EC 3.1.3.16)
(PP4C) (Pp4) (Protein phosphatase X) (PP-X).
[Source:Uniprot/SWISSPROT;Acc:P60510]
(307 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
08242 551 e-157
06084 340 6e-94
01173 295 1e-80
06264 291 2e-79
25536 219 1e-57
19040 172 2e-43
18336 108 8e-30
30980 95 3e-20
18967 91 6e-19
21146 89 3e-18
04295 65 3e-11
36367 41 6e-04
25813 27 9.7
>08242
Length = 3368
Score = 551 bits (1419), Expect = e-157, Method: Compositional matrix adjust.
Identities = 260/274 (94%), Positives = 267/274 (97%)
Frame = -1
Query: 34 EILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVGGDVPETNYLFMGDFVDRGFYSVET 93
EILVEESNVQRVDSPVTVCGDIHGQFYDLKELF+VGGDVP+TNYLFMGDFVDRGFYSVET
Sbjct: 3368 EILVEESNVQRVDSPVTVCGDIHGQFYDLKELFKVGGDVPDTNYLFMGDFVDRGFYSVET 3189
Query: 94 FLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLRKYGSVTVWRYCTEIFDYLSLS 153
FLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLRKYGS+TVWRYCTEIFDYLSLS
Sbjct: 3188 FLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLRKYGSITVWRYCTEIFDYLSLS 3009
Query: 154 AIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSDPEDTTGWGVSPRGA 213
AIIDGKIFCVHGGLSPSIQTLDQIR+IDRKQEVPHDGPMCDLLWSDPED GWGVSPRGA
Sbjct: 3008 AIIDGKIFCVHGGLSPSIQTLDQIRSIDRKQEVPHDGPMCDLLWSDPEDMQGWGVSPRGA 2829
Query: 214 GYLFGSDVVAQFNAANDIDMICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAIL 273
GYLFGSDVV+QFNAAN ID+ICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAIL
Sbjct: 2828 GYLFGSDVVSQFNAANXIDLICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAIL 2649
Query: 274 ELDEHLQKDFIIFEAAPQETRGIPSKKPVADYFL 307
ELDEHLQ+DF IFEAAPQE RGIPSKKP DYFL
Sbjct: 2648 ELDEHLQRDFTIFEAAPQEARGIPSKKPQPDYFL 2547
>06084
Length = 1739
Score = 340 bits (871), Expect = 6e-94, Method: Compositional matrix adjust.
Identities = 157/252 (62%), Positives = 199/252 (78%)
Frame = -2
Query: 56 HGQFYDLKELFRVGGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNH 115
HGQFYDL ELF+ GG++P+TNY+FMGDFVDRG++S+ETF LLL LK ++PD+I L+RGNH
Sbjct: 1738 HGQFYDLMELFKTGGEMPDTNYVFMGDFVDRGYFSLETFTLLLTLKAKWPDKIVLLRGNH 1559
Query: 116 ESRQITQVYGFYDECLRKYGSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLD 175
ESRQITQ+YGFYDEC KYG+ WRYC +FD L+++AIID I CVHGGLSP I+T+D
Sbjct: 1558 ESRQITQIYGFYDECQTKYGNANAWRYCCRVFDLLTIAAIIDECILCVHGGLSPDIKTID 1379
Query: 176 QIRTIDRKQEVPHDGPMCDLLWSDPEDTTGWGVSPRGAGYLFGSDVVAQFNAANDIDMIC 235
QIRTI+R QE+PH G CDL+WSDPED W +SPRGAG+LFG+ V A+F A+N++ +IC
Sbjct: 1378 QIRTIERNQEIPHKGAFCDLVWSDPEDVDTWAMSPRGAGWLFGAKVTAEFVASNNLKLIC 1199
Query: 236 RAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQKDFIIFEAAPQETRG 295
RAHQLV EGYK+ F+E ++TVWSAPNYCYRCGN+AA+L + + +F+A P R
Sbjct: 1198 RAHQLVHEGYKYMFDEKLVTVWSAPNYCYRCGNIAAVLSFTDAEHHEAKLFKAVPDSERV 1019
Query: 296 IPSKKPVADYFL 307
IP + YFL
Sbjct: 1018 IPPRTQTP-YFL 986
>01173
Length = 2619
Score = 295 bits (755), Expect = 1e-80, Method: Compositional matrix adjust.
Identities = 138/288 (47%), Positives = 202/288 (70%), Gaps = 4/288 (1%)
Frame = -1
Query: 20 IKESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVGGDVPETNYLF 79
+ ESE++ LC K+REI + + + +++P+ +CGDIHGQ+YDL LF GG PE+NYLF
Sbjct: 2607 LTESEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLF 2428
Query: 80 MGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLRKYGSVTV 139
+GD+VDRG S+ET LLLA K++YP+ L+RGNHE I ++YGFYDEC R+Y ++ +
Sbjct: 2427 LGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRY-NIKL 2251
Query: 140 WRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSD 199
W+ T+ F+ L ++AIID KIFC HGGLSP +Q+++QIR I R +VP G +CDLLWSD
Sbjct: 2250 WKTFTDCFNCLPIAAIIDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSD 2071
Query: 200 PE-DTTGWGVSPRGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGYKWHFNETVLTVWS 258
P+ +T GWG + RG + FG++VVA+F +D+D+ICRAHQ+V +GY++ ++T++S
Sbjct: 2070 PDKETMGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFS 1891
Query: 259 APNYCYRCGNVAAILELDEHLQKDFIIFEAAPQET---RGIPSKKPVA 303
APNYC N A++ +DE L F I + A ++ G+ +PV
Sbjct: 1890 APNYCGEFDNAGAMMSVDETLMCSFQILKPADKKKFPYGGLNQGRPVT 1747
>06264
Length = 999
Score = 291 bits (746), Expect = 2e-79, Method: Compositional matrix adjust.
Identities = 137/284 (48%), Positives = 199/284 (70%), Gaps = 4/284 (1%)
Frame = -3
Query: 24 EVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVGGDVPETNYLFMGDF 83
E++ LC K+REI + + + +++P+ +CGDIHGQ+YDL LF GG PE+NYLF+GD+
Sbjct: 997 EIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDY 818
Query: 84 VDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLRKYGSVTVWRYC 143
VDRG S+ET LLLA K++YP+ L+RGNHE I ++YGFYDEC R+Y ++ +W+
Sbjct: 817 VDRGRQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRY-NIKLWKTF 641
Query: 144 TEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSDPE-D 202
T+ F+ L ++AIID KIFC HGGLSP +Q+++QIR I R +VP G +CDLLWSDP+ +
Sbjct: 640 TDCFNCLPIAAIIDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKE 461
Query: 203 TTGWGVSPRGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGYKWHFNETVLTVWSAPNY 262
T GWG S RG + FG++VVA+F +D+D+ICRAHQ+V +GY++ ++T++SAPNY
Sbjct: 460 TMGWGESDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNY 281
Query: 263 CYRCGNVAAILELDEHLQKDFIIFEAAPQET---RGIPSKKPVA 303
C N A++ +DE L F I + A ++ G+ +PV
Sbjct: 280 CGEFDNAGAMMSVDETLMCSFQILKPADKKKFPYGGLSXGRPVT 149
>25536
Length = 486
Score = 219 bits (558), Expect = 1e-57, Method: Compositional matrix adjust.
Identities = 101/144 (70%), Positives = 121/144 (84%)
Frame = +1
Query: 2 AEISDLDRQIEQLRRCELIKESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYD 61
A DLD+ IEQL C+ + E++VK LC KA+EIL +ESNVQ V PVTVCGD+HGQF+D
Sbjct: 55 AAAKDLDQWIEQLNDCKQLSENQVKTLCEKAKEILSKESNVQEVKCPVTVCGDVHGQFHD 234
Query: 62 LKELFRVGGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQIT 121
L ELFR+GG P+TNYLFMGD+VDRG+YSVET LL+ALKVR+ DRIT++RGNHESRQIT
Sbjct: 235 LMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVSLLVALKVRFRDRITILRGNHESRQIT 414
Query: 122 QVYGFYDECLRKYGSVTVWRYCTE 145
QVYGFYDECLRKYG+ VW+Y T+
Sbjct: 415 QVYGFYDECLRKYGNANVWKYFTD 486
>19040
Length = 452
Score = 172 bits (436), Expect = 2e-43, Method: Compositional matrix adjust.
Identities = 78/151 (51%), Positives = 110/151 (72%)
Frame = -3
Query: 26 KALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVGGDVPETNYLFMGDFVD 85
+ LC K+REI +++ + +++P+ +CGDIHGQ+ DL LF GG P NYLF+GD+VD
Sbjct: 450 RGLCLKSREIFLQQPILLELEAPLIICGDIHGQYTDLLRLFEYGGFPPAANYLFLGDYVD 271
Query: 86 RGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLRKYGSVTVWRYCTE 145
RG S+ET LLLA K++YP+ L+RGNHE I ++YGFYDEC R+Y +V +W+ T+
Sbjct: 270 RGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRY-NVKLWKTFTD 94
Query: 146 IFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQ 176
F+ L ++AIID KIFC HGGLSP +Q ++Q
Sbjct: 93 CFNCLPVAAIIDEKIFCCHGGLSPDLQGMEQ 1
>18336
Length = 465
Score = 108 bits (269), Expect(3) = 8e-30, Method: Compositional matrix adjust.
Identities = 52/95 (54%), Positives = 67/95 (70%)
Frame = +2
Query: 32 AREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVGGDVPETNYLFMGDFVDRGFYSV 91
+R IL E + R+ S +CGDIHGQ+YDL LF GG PE+NYLF+GD+VDRG S+
Sbjct: 50 SRNIL-ESAYSFRIRSTT*ICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSL 226
Query: 92 ETFLLLLALKVRYPDRITLIRGNHESRQITQVYGF 126
ET LLLA K++YP+ L+RGNHE I ++YGF
Sbjct: 227 ETICLLLAYKIKYPENFFLLRGNHECASINRIYGF 331
Score = 36.6 bits (83), Expect(3) = 8e-30, Method: Compositional matrix adjust.
Identities = 18/37 (48%), Positives = 27/37 (72%)
Frame = +1
Query: 127 YDECLRKYGSVTVWRYCTEIFDYLSLSAIIDGKIFCV 163
YDEC R+Y ++ +W+ T+ F+ L ++AIID KIF V
Sbjct: 331 YDECKRRY-NIKLWKTFTDCFNCLPIAAIIDVKIFVV 438
Score = 23.5 bits (49), Expect(3) = 8e-30, Method: Compositional matrix adjust.
Identities = 8/12 (66%), Positives = 9/12 (75%)
Frame = +3
Query: 161 FCVHGGLSPSIQ 172
C HGGLSP +Q
Sbjct: 429 LCCHGGLSPDLQ 464
>30980
Length = 765
Score = 95.1 bits (235), Expect = 3e-20, Method: Compositional matrix adjust.
Identities = 46/84 (54%), Positives = 60/84 (71%), Gaps = 1/84 (1%)
Frame = +3
Query: 225 FNAANDIDMICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQKDFI 284
FN +N + +I RAHQLVMEGY W + V+T++SAPNYCYRCGN AAI+ELD+ L+ F+
Sbjct: 6 FNHSNGLTLISRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDALKYSFL 185
Query: 285 IFEAAPQETRGIPS-KKPVADYFL 307
F+ AP+ RG P + DYFL
Sbjct: 186 QFDPAPR--RGEPHVTRRTPDYFL 251
>18967
Length = 440
Score = 90.9 bits (224), Expect = 6e-19, Method: Compositional matrix adjust.
Identities = 44/77 (57%), Positives = 52/77 (67%)
Frame = +2
Query: 231 IDMICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQKDFIIFEAAP 290
+D+ICRAHQLV EG K+ F ++TVWSAPNYCYRCGNVAAIL + Q+ IF A P
Sbjct: 2 LDLICRAHQLVNEGIKYMFEGKLVTVWSAPNYCYRCGNVAAILSFETAQQRQTKIFLAVP 181
Query: 291 QETRGIPSKKPVADYFL 307
R IP K+ YFL
Sbjct: 182 DSERVIP-KQNTTPYFL 229
>21146
Length = 408
Score = 88.6 bits (218), Expect = 3e-18, Method: Compositional matrix adjust.
Identities = 38/58 (65%), Positives = 44/58 (75%)
Frame = +3
Query: 190 GPMCDLLWSDPEDTTGWGVSPRGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGYKW 247
GPMCDLLWSDP+D GWG+SPRGAGY FG D+ FN +N + +I RAHQLVME W
Sbjct: 117 GPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHSNGLTLISRAHQLVMEVMFW 290
>04295
Length = 748
Score = 65.5 bits (158), Expect = 3e-11, Method: Compositional matrix adjust.
Identities = 30/88 (34%), Positives = 54/88 (61%), Gaps = 4/88 (4%)
Frame = -1
Query: 220 DVVAQFNAANDIDMICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHL 279
DVV++F +D+D+I RAHQ+V +GY++ ++T++SAPNYC N ++ +DE L
Sbjct: 745 DVVSKFLNRHDLDLITRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETL 566
Query: 280 QKDFIIFEAAPQETR----GIPSKKPVA 303
F I + + ++ + G+ S +P+
Sbjct: 565 MCSFQILKPSEKKAKYQYGGLNSGRPIT 482
>36367
Length = 827
Score = 41.2 bits (95), Expect = 6e-04, Method: Compositional matrix adjust.
Identities = 36/132 (27%), Positives = 58/132 (43%), Gaps = 22/132 (16%)
Frame = +1
Query: 164 HGGL-SPSIQTLDQIRTIDRKQEVPH-----DGPMC-DLLWSDP--------------ED 202
HGG+ SP + + I+ K VP D PM ++LWSDP ++
Sbjct: 1 HGGIPSPENEGGGHLEAIN-KIPVPLSDPEVDSPMAWEILWSDPISVDLVSPEVLKDMKE 177
Query: 203 TTGWGV-SPRGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGYKWHFNETVLTVWSAPN 261
G+ S RG + F + + F N + + RAH++ G++ +LTV+S+
Sbjct: 178 HHGFTFNSRRGTAHFFSCNALLAFLERNGLSHVIRAHEVQEVGFQVQQQGKLLTVFSSSR 357
Query: 262 YCYRCGNVAAIL 273
YC A +L
Sbjct: 358 YCGGSNEAACVL 393
>25813
Length = 1610
Score = 26.9 bits (58), Expect = 9.7, Method: Compositional matrix adjust.
Identities = 25/104 (24%), Positives = 38/104 (36%), Gaps = 1/104 (0%)
Frame = +1
Query: 188 HDGPMCDLLWSDPEDTTGWGVSPRGAGYLFGSDVVAQFNAANDIDMI-CRAHQLVMEGYK 246
H G +CD DP+ W + G L S + Q A + CR+H
Sbjct: 292 HRGQLCDYSEVDPQPAGHWHRKRQNTGELGRSSEIRQCGAVQKTHHVPCRSHD------- 450
Query: 247 WHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQKDFIIFEAAP 290
+ + V + P+ C V A L + FI + A+P
Sbjct: 451 --WRQWVSAAQTFPD----CAAVHAFWSLSAYAGLFFIGYAASP 564
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000310572 | hsapiens_gene_ensembl | 26S protease
regulatory subunit 8 (Proteasome 26S subunit ATPase 5) (Proteasome
subunit p45) (p45/SUG) (Thyroid hormone receptor- interacting protein
1) (TRIP1). [Source:Uniprot/SWISSPROT;Acc:P62195]
(406 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
19129 548 e-156
07243 315 1e-86
23766 271 1e-84
01642 285 2e-77
07247 237 2e-74
02582 177 5e-45
12235 160 1e-39
03022 150 8e-37
26408 123 2e-28
00810 107 8e-24
20270 103 2e-22
38672 83 3e-21
25671 84 1e-16
02194 67 1e-11
17843 62 3e-10
26887 51 7e-07
06766 45 6e-05
19561 44 1e-04
14413 44 1e-04
01279 34 0.086
37695 34 0.12
05247 32 0.47
02744 31 0.94
>19129
Length = 1020
Score = 548 bits (1412), Expect = e-156, Method: Compositional matrix adjust.
Identities = 272/321 (84%), Positives = 284/321 (88%), Gaps = 1/321 (0%)
Frame = +1
Query: 7 EQMELEEGKAG-SGLRQYYLSKIEELQLIVNDKSQNLRRLQAQRNELNAKVXXXXXXXXX 65
EQME+E G G++QYY+SKIEE QLIVN+K+QNLRRL+AQRNELNAKV
Sbjct: 58 EQMEIEGAPVGHEGIKQYYISKIEEQQLIVNEKTQNLRRLEAQRNELNAKVRMLREELQL 237
Query: 66 XXXXGSYVGEVVRAMDKKKVLVKVHPEGKFXXXXXXXXXXXXXTPNCRVALRNDSYTLHK 125
GSYVGEVV+ MDKKKVLVKVHPEGKF TPNCRVALRNDSY LHK
Sbjct: 238 LQEQGSYVGEVVKPMDKKKVLVKVHPEGKFVVDIDKNIDMNSVTPNCRVALRNDSYVLHK 417
Query: 126 ILPNKVDPLVSLMMVEKVPDSTYEMIGGLDKQIKEIKEVIELPVKHPELFEALGIAQPKG 185
ILPNKVDPLVSLMMVEKVPDSTYEM+GGLDKQIKEIKEVIELPVKHPELFEALGIAQPKG
Sbjct: 418 ILPNKVDPLVSLMMVEKVPDSTYEMVGGLDKQIKEIKEVIELPVKHPELFEALGIAQPKG 597
Query: 186 VLLYGPPGTGKTLLARAVAHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMAREHAPSI 245
VLLYGPPGTGKTLLARAVAHHT+CTFIRVSGSELVQKFIGEG+RMVRELFVMAREHAPSI
Sbjct: 598 VLLYGPPGTGKTLLARAVAHHTECTFIRVSGSELVQKFIGEGSRMVRELFVMAREHAPSI 777
Query: 246 IFMDEIDSIGSSRLEGGSGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDILDSAL 305
IFMDEIDSIGSSRLEGGSGGDSEVQRTMLELLNQLDGFE +NIKVIMATNRIDILDSAL
Sbjct: 778 IFMDEIDSIGSSRLEGGSGGDSEVQRTMLELLNQLDGFEPKQNIKVIMATNRIDILDSAL 957
Query: 306 LRPGRIDRKIEFPPPNEEARL 326
LRPGRIDRKIEFPPPNEEARL
Sbjct: 958 LRPGRIDRKIEFPPPNEEARL 1020
>07243
Length = 1112
Score = 315 bits (808), Expect = 1e-86, Method: Compositional matrix adjust.
Identities = 157/278 (56%), Positives = 201/278 (72%)
Frame = +1
Query: 113 RVALRNDSYTLHKILPNKVDPLVSLMMVEKVPDSTYEMIGGLDKQIKEIKEVIELPVKHP 172
RVAL + T+ + LP +VDPLV M E D TY IGGL +QI+E++EVIELP+ +P
Sbjct: 97 RVALDMTTLTIMRYLPREVDPLVYNMSHEDPGDVTYSAIGGLTEQIRELREVIELPLLNP 276
Query: 173 ELFEALGIAQPKGVLLYGPPGTGKTLLARAVAHHTDCTFIRVSGSELVQKFIGEGARMVR 232
ELF +GI PKG LLYGPPGTGKTLLARAVA D F++V S +V K+IGE AR++R
Sbjct: 277 ELFLRVGITPPKGCLLYGPPGTGKTLLARAVASQLDANFLKVVSSAIVDKYIGESARLIR 456
Query: 233 ELFVMAREHAPSIIFMDEIDSIGSSRLEGGSGGDSEVQRTMLELLNQLDGFEATKNIKVI 292
E+F AR+H P IIFMDEID+IG R G+ D E+QRT++ELLNQ+DGF++ +K+I
Sbjct: 457 EMFNYARDHQPCIIFMDEIDAIGGRRFSEGTSADREIQRTLMELLNQMDGFDSLGQVKMI 636
Query: 293 MATNRIDILDSALLRPGRIDRKIEFPPPNEEARLDILKIHSRKMNLTRGINLRKIAELMP 352
MATNR D LD ALLRPGR+DRKIE P PNE+ARL+ILKIH+ + I+ I +L
Sbjct: 637 MATNRPDTLDPALLRPGRLDRKIEIPLPNEQARLEILKIHALIIAKHGEIDYEAIVKLSD 816
Query: 353 GASGAEVKGVCTEAGMYALRERRVHVTQEDFEMAVAKV 390
+GA+++ VCTEAG++A+R R +V QEDF AV KV
Sbjct: 817 NFNGADLRNVCTEAGLFAIRAEREYVIQEDFMKAVRKV 930
>23766
Length = 1463
Score = 271 bits (692), Expect(2) = 1e-84, Method: Compositional matrix adjust.
Identities = 127/218 (58%), Positives = 166/218 (76%)
Frame = +1
Query: 179 GIAQPKGVLLYGPPGTGKTLLARAVAHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMA 238
G PKGV+LYGPPGTGKTLLA+AVA+ T TF+RV GSEL+QK++G+G ++VRELF +A
Sbjct: 142 GNQAPKGVILYGPPGTGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVA 321
Query: 239 REHAPSIIFMDEIDSIGSSRLEGGSGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRI 298
EHAPSI+F+DEID++G+ R E SGG+ E+QRTMLELLNQLDGF++ ++KVIMATNRI
Sbjct: 322 EEHAPSIVFIDEIDAVGTKRYESNSGGEREIQRTMLELLNQLDGFDSRGDVKVIMATNRI 501
Query: 299 DILDSALLRPGRIDRKIEFPPPNEEARLDILKIHSRKMNLTRGINLRKIAELMPGASGAE 358
+ LD AL+RPGRIDRKIEFP P+E+ + I IH+ +M L +N+ SGA+
Sbjct: 502 ETLDPALIRPGRIDRKIEFPLPDEKTKRRIFTIHTSRMTLAGDVNIDDYVMSKDDLSGAD 681
Query: 359 VKGVCTEAGMYALRERRVHVTQEDFEMAVAKVMQKDSE 396
+K +CTEAG+ ALRERR+ V EDF A V+ + +E
Sbjct: 682 IKAICTEAGLLALRERRMKVRNEDFAKAKENVLYRKNE 795
Score = 60.5 bits (145), Expect(2) = 1e-84, Method: Compositional matrix adjust.
Identities = 29/53 (54%), Positives = 37/53 (69%), Gaps = 1/53 (1%)
Frame = +2
Query: 133 PLVSLMM-VEKVPDSTYEMIGGLDKQIKEIKEVIELPVKHPELFEALGIAQPK 184
P+V++M EK P TY IGGLD QI+EIKE +ELP+ HPE +E +GI K
Sbjct: 2 PMVTVMKGWEKAPQETYADIGGLDTQIQEIKESVELPLTHPEYYEEMGIKHQK 160
>01642
Length = 1406
Score = 285 bits (729), Expect = 2e-77, Method: Compositional matrix adjust.
Identities = 135/267 (50%), Positives = 185/267 (69%)
Frame = -1
Query: 128 PNKVDPLVSLMMVEKVPDSTYEMIGGLDKQIKEIKEVIELPVKHPELFEALGIAQPKGVL 187
P ++ + + + P Y IGG+D Q +E++E +ELP+ H EL++ +GI P+GVL
Sbjct: 1058 PQRLTAVSQCFKLMRSPT*XYSDIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVL 879
Query: 188 LYGPPGTGKTLLARAVAHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMAREHAPSIIF 247
+YGPPG GKT+LA+AVAHHT FIRV GSE VQK++GEG RMVR++F +A+E+AP+IIF
Sbjct: 878 MYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIF 699
Query: 248 MDEIDSIGSSRLEGGSGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDILDSALLR 307
+DEID+I + R + +G D EVQR +LELLNQ+DGF+ T N+KVIMATNR D LD ALLR
Sbjct: 698 IDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQTVNVKVIMATNRADTLDPALLR 519
Query: 308 PGRIDRKIEFPPPNEEARLDILKIHSRKMNLTRGINLRKIAELMPGASGAEVKGVCTEAG 367
PGR+DRKIEFP P+ + I + KMN++ ++L SGA++ +C EAG
Sbjct: 518 PGRLDRKIEFPLPDRRQKRLIFSTITGKMNISEEVDLEDYVARPDKISGADINAICQEAG 339
Query: 368 MYALRERRVHVTQEDFEMAVAKVMQKD 394
M A+RE R V +DFE ++KD
Sbjct: 338 MQAVRENRYVVLAKDFEKGYKNNIKKD 258
>07247
Length = 1753
Score = 237 bits (605), Expect(2) = 2e-74, Method: Compositional matrix adjust.
Identities = 113/199 (56%), Positives = 146/199 (73%)
Frame = -2
Query: 192 PGTGKTLLARAVAHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMAREHAPSIIFMDEI 251
PGTGKTLLARAVA DC F++V S +V K+IGE AR++RE+F AR+H P IIFMDEI
Sbjct: 1407 PGTGKTLLARAVASQLDCNFLKVVSSAIVDKYIGESARLIREMFAFARDHEPCIIFMDEI 1228
Query: 252 DSIGSSRLEGGSGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDILDSALLRPGRI 311
D+IG R G+ D E+QRT++ELLNQ+DGF+A +K+IMATNR D LD ALLRPGR+
Sbjct: 1227 DAIGGRRFSEGTSADREIQRTLMELLNQMDGFDALGQVKMIMATNRPDTLDPALLRPGRL 1048
Query: 312 DRKIEFPPPNEEARLDILKIHSRKMNLTRGINLRKIAELMPGASGAEVKGVCTEAGMYAL 371
DRKIE PNE+ARL+ILKIH+ + I+ + +L +GA+++ VCTEAGM+A+
Sbjct: 1047 DRKIEISLPNEQARLEILKIHANPIAKHGEIDWEAVVKLSEDFNGADLRNVCTEAGMFAI 868
Query: 372 RERRVHVTQEDFEMAVAKV 390
R R +V +EDF AV KV
Sbjct: 867 RAERDYVIEEDFMKAVRKV 811
Score = 60.1 bits (144), Expect(2) = 2e-74, Method: Compositional matrix adjust.
Identities = 29/61 (47%), Positives = 41/61 (67%)
Frame = -1
Query: 131 VDPLVSLMMVEKVPDSTYEMIGGLDKQIKEIKEVIELPVKHPELFEALGIAQPKGVLLYG 190
+DPLV M VE D T+ IGGL +Q++E++EVIELP+ +PELF+ +GI + K
Sbjct: 1588 MDPLVYNMSVEDPGDITFNQIGGLGEQVRELREVIELPLLNPELFQRVGITRLKAACCSD 1409
Query: 191 P 191
P
Sbjct: 1408 P 1406
>02582
Length = 1101
Score = 177 bits (450), Expect = 5e-45, Method: Compositional matrix adjust.
Identities = 106/293 (36%), Positives = 165/293 (56%), Gaps = 34/293 (11%)
Frame = +3
Query: 148 YEMIGGLDKQIKEIKEVIELPVKHPELFEALGIAQPKGVLLYGPPGTGKTLLARAVAHHT 207
+ IGGLD +I++ +E P+ +P+ F+ALG+ KGVLLYGPPG GKT LA+A A
Sbjct: 138 WTDIGGLDLVKLQIRQAVEWPLLYPDTFQALGLPLTKGVLLYGPPGCGKTTLAQAAATAC 317
Query: 208 DCTFIRVSGSELVQKFIGEGARMVRELFVMAREHAPSIIFMDEIDSIGSSRLEGGSGGDS 267
TF+ +S ++L ++G+ + + E F AR APSI+F+DE+D+I R + S G
Sbjct: 318 HVTFLSLSCAQLYSPYVGDAEKKISETFQKARALAPSILFLDEMDAIVGKRSD-SSLGSG 494
Query: 268 EVQRTMLELLNQLDGF-------------------------------EA-TKNIKVIMAT 295
+R + LLN++DG EA +++ V+ AT
Sbjct: 495 VSERVLSALLNEMDGIGVRLDDKSDSREMEIEGSSDHTPQVRQHAVKEAHDRHVLVVAAT 674
Query: 296 NRIDILDSALLRPGRIDRKIEFPPPNEEARLDILKIHSRKMNLTRGINLRKIAELMPGAS 355
NR D+LD ALLRPGR+DR I PPP+ + RL IH+RKM L + ++++++A+L G +
Sbjct: 675 NRPDMLDPALLRPGRMDRLIYVPPPDVQGRLQSFTIHTRKMPLGKDVDVKQLADLTAGYT 854
Query: 356 GAEVKGVCTEAGMYALRERRVH--VTQEDFEMAVAKVMQKDSEKNMSIKKLWK 406
GA++K +C E G+ AL+E V Q+ F A+ S + ++ ++K
Sbjct: 855 GADIKTLCNEVGLLALKESMSAECVNQDHFLNAIKTRKPSLSADSSEVETMYK 1013
>12235
Length = 1749
Score = 160 bits (404), Expect = 1e-39, Method: Compositional matrix adjust.
Identities = 80/183 (43%), Positives = 115/183 (62%), Gaps = 2/183 (1%)
Frame = +1
Query: 211 FIRVSGSELVQKFIGEGARMVRELFVMAREHAPSIIFMDEIDSIGSSRLEGGSGGDSEVQ 270
FI VSGSE ++ F+G G VR++F AR++AP I+F+DEID++G R GG SE +
Sbjct: 16 FITVSGSEFLEMFVGVGPSRVRDMFATARKNAPCILFVDEIDAVGRKRSGRNFGGQSEQE 195
Query: 271 RTMLELLNQLDGFEATKNIKVIMATNRIDILDSALLRPGRIDRKIEFPPPNEEARLDILK 330
T+ +LL ++DGF + V+ ATNR+DILD+ALLRPGR DR+I P P+ + R I K
Sbjct: 196 NTLNQLLVEMDGFNTQTGVVVLAATNRVDILDAALLRPGRFDRQIFVPLPDIKXRASIFK 375
Query: 331 IH--SRKMNLTRGINLRKIAELMPGASGAEVKGVCTEAGMYALRERRVHVTQEDFEMAVA 388
+H K + + RK+A L PG SGA++ VC EA + A R+ + FE A+
Sbjct: 376 VHLDPLKTEVNKNDLARKMAALTPGFSGADIANVCNEAALIAARDLNTSIHMTHFEQAIE 555
Query: 389 KVM 391
+V+
Sbjct: 556 RVV 564
>03022
Length = 2255
Score = 150 bits (379), Expect = 8e-37, Method: Compositional matrix adjust.
Identities = 89/248 (35%), Positives = 140/248 (56%), Gaps = 4/248 (1%)
Frame = +2
Query: 130 KVDPLVSLMMVEKVPDSTYEMIGGLDKQIKEIKEVIELPVKHPELFEALGIAQPKGVLLY 189
K P VP +T+E +G L ++K+ I + PE+ A G+ G++L
Sbjct: 1370 KAQPAAKREGFATVPTTTWEDVGALSNVRAQLKDSILCRIHDPEVSSAFGLPTNSGIILV 1549
Query: 190 GPPGTGKTLLARAVAHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMAREHAPSIIFMD 249
GPPG GKTL+A+A+A+ FI + G EL+ K++GE R +RE F A+ AP +IF D
Sbjct: 1550 GPPGCGKTLVAKAMANEAGLNFIYIKGPELLDKYVGESERNLREKFDKAQACAPCLIFFD 1729
Query: 250 EIDSIGSSRL--EGGSGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDILDSALLR 307
E+D++ S+R +G + G S +LL +DG + V+ ATN I+ +D AL R
Sbjct: 1730 EMDTLCSNRQNNDGSNVGKSVTN----QLLALMDGCGERSQVYVMGATNIIENVDPALQR 1897
Query: 308 PGRIDRKIEFPPPNEEARLDILKIHSRKMNLTR--GINLRKIAELMPGASGAEVKGVCTE 365
PGR DRKI P+ + RLDIL+ ++ + + +++++A+ G SGA++K + E
Sbjct: 1898 PGRFDRKIFIGLPDTDGRLDILRALTKGGSQRKLESCDMQQLAQDTEGFSGADLKHLVNE 2077
Query: 366 AGMYALRE 373
A AL+E
Sbjct: 2078 ASTIALKE 2101
Score = 53.1 bits (126), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 30/116 (25%), Positives = 56/116 (48%), Gaps = 2/116 (1%)
Frame = +1
Query: 142 KVPDSTYEMIGGLDKQIKEIKEVIE--LPVKHPELFEALGIAQPKGVLLYGPPGTGKTLL 199
+P +T + GG +K + E+ E L + + A + LLYGP G+GK L
Sbjct: 508 SIPTATLDDFGGSNKLLAELDSDFEEILYSDYCQYASACDQKACRRYLLYGPRGSGKRFL 687
Query: 200 ARAVAHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMAREHAPSIIFMDEIDSIG 255
A +A ++ + L+ G+ + VR+LF A AP ++++++I+ +
Sbjct: 688 AECIAGQLKLPLLKPKINTLISGVSGDSEQRVRDLFDQAVSQAPCVLYLEDIECLA 855
>26408
Length = 463
Score = 123 bits (308), Expect = 2e-28, Method: Compositional matrix adjust.
Identities = 78/142 (54%), Positives = 87/142 (61%), Gaps = 4/142 (2%)
Frame = +1
Query: 70 GSYVGEVVRAMDKKKVLVKVHPEGKFXXXXXXXXXXXXXTPN--CRVALRNDSYTLHKIL 127
GSYVGEVV+ MDKKKVLVKVHPEGKF CR A R LH
Sbjct: 25 GSYVGEVVKPMDKKKVLVKVHPEGKFVVDFGQEY*YKRCYAQLPCRTAQRK----LHTTQ 192
Query: 128 PNKVDPLVSLMMVEKVPDSTYEMIGG--LDKQIKEIKEVIELPVKHPELFEALGIAQPKG 185
+ + + + + + G L + IKEVIELPVKHPELF+ALGIAQPKG
Sbjct: 193 DLAKQSGSASFVDDGRKSARFNIRNGWWLG*ANQRIKEVIELPVKHPELFDALGIAQPKG 372
Query: 186 VLLYGPPGTGKTLLARAVAHHT 207
VLLYGPPGTGKTLLARAVAHHT
Sbjct: 373 VLLYGPPGTGKTLLARAVAHHT 438
Score = 122 bits (306), Expect = 3e-28, Method: Compositional matrix adjust.
Identities = 62/107 (57%), Positives = 69/107 (64%)
Frame = +2
Query: 109 TPNCRVALRNDSYTLHKILPNKVDPLVSLMMVEKVPDSTYEMIGGLDKQIKEIKEVIELP 168
TPNCRVALRN+SYTLHKILPNKVDPLVSLMMVEKVPDSTYEM+GGLDKQIKE + P
Sbjct: 143 TPNCRVALRNESYTLHKILPNKVDPLVSLMMVEKVPDSTYEMVGGLDKQIKESRR*SNCP 322
Query: 169 VKHPELFEALGIAQPKGVLLYGPPGTGKTLLARAVAHHTDCTFIRVS 215
P + + P K L + +CTFIRVS
Sbjct: 323 SSIPNCSMPWALLSQRVYCCTVRPVLAKRCLPVRLPITPECTFIRVS 463
>00810
Length = 1431
Score = 107 bits (267), Expect = 8e-24, Method: Compositional matrix adjust.
Identities = 72/223 (32%), Positives = 120/223 (53%), Gaps = 3/223 (1%)
Frame = -3
Query: 154 LDKQIKEIKEVIELPVKHPELFEALGIAQP-KGVLLYGPPGTGKTLLARAVAHHTDCTFI 212
L+ I+++KE + LP K +LF + QP KGVLL+GPPG GKT++A+A A FI
Sbjct: 1429 LEDVIQDVKETVILPFKRADLFRHSSLLQPPKGVLLHGPPGCGKTMIAKATAKAAGARFI 1250
Query: 213 RVSGSELVQKFIGEGARMVRELFVMAREHAPSIIFMDEIDSIGSSRLEGGSGGDSEVQRT 272
+ S LV K+ GE + +F +A + P+IIF+DEIDS SR + ++
Sbjct: 1249 NLQVSSLVDKWYGESQKRAEAVFSLAIKLQPTIIFIDEIDSFLRSRTSTDHEATAMIK-- 1076
Query: 273 MLELLNQLDGFEATKNIKVIM--ATNRIDILDSALLRPGRIDRKIEFPPPNEEARLDILK 330
+ ++ DG + +V++ ATNR +D+A+LR I P P + + L
Sbjct: 1075 -TQFMSFWDGLMTDPDCRVMVMGATNRPQDVDAAILRRMPSMFHIGLPGPAQRRSIFNLI 899
Query: 331 IHSRKMNLTRGINLRKIAELMPGASGAEVKGVCTEAGMYALRE 373
+ +++ +N ++AE+ G SG++++ VC A + + E
Sbjct: 898 LSKERID---ALNYDELAEMTDGFSGSDIREVCRAAAVATVHE 779
>20270
Length = 542
Score = 103 bits (256), Expect = 2e-22, Method: Compositional matrix adjust.
Identities = 58/126 (46%), Positives = 80/126 (63%), Gaps = 2/126 (1%)
Frame = -3
Query: 184 KGVLLYGPPGTGKTLLARAVAHH-TDCTFIRVSGSELVQKFIGEGARMVRELFVMAREHA 242
+G+LLYGPPGTGK+ LA+AVA + TF VS S+LV K++GE ++V+ LF +ARE+
Sbjct: 378 RGILLYGPPGTGKSYLAKAVATEANNSTFFSVSSSDLVSKWLGESEKLVKTLFQLARENQ 199
Query: 243 PSIIFMDEIDSIGSSRLEGGSGGDSEVQRTMLELLNQLDGF-EATKNIKVIMATNRIDIL 301
PSIIF+DE+D++ SR E S +R E L Q+ G + V+ ATN L
Sbjct: 198 PSIIFIDEVDALCGSRSENES---ESARRIKTEFLVQMQGVGNDNTGVLVLGATNIPWTL 28
Query: 302 DSALLR 307
DSA+ R
Sbjct: 27 DSAIRR 10
>38672
Length = 730
Score = 82.8 bits (203), Expect(2) = 3e-21, Method: Compositional matrix adjust.
Identities = 46/140 (32%), Positives = 79/140 (56%), Gaps = 18/140 (12%)
Frame = -3
Query: 268 EVQRTML-ELLNQLDGFEATKNIKVIMATNRIDILDSALLRPGRIDRKIEFPPPNEEARL 326
EV+R ++ +LL +DG + ++ V+ ATNR + +D+AL R GR DR+++ P+ RL
Sbjct: 596 EVERRIVSQLLTLMDGLKQRSHVIVMAATNRPNSVDAALRRFGRFDREVDIGIPDATGRL 417
Query: 327 DILKIHSRKMNLTRGINLRKIAELMPGASGAEVKGVCTEAGMYALRER------------ 374
+IL+IH++ M L ++L ++A G GA+V +C+EA + +RE+
Sbjct: 416 EILRIHTKNMKLADDVDLEQVASETHGHVGADVAALCSEAALQQIREKMDLIDLEDDTID 237
Query: 375 -----RVHVTQEDFEMAVAK 389
+ VT +DF A+ K
Sbjct: 236 AEVLDSLAVTMDDFRWALGK 177
Score = 36.6 bits (83), Expect(2) = 3e-21, Method: Compositional matrix adjust.
Identities = 16/40 (40%), Positives = 26/40 (65%)
Frame = -1
Query: 219 LVQKFIGEGARMVRELFVMAREHAPSIIFMDEIDSIGSSR 258
++ K GE +R+ F A ++AP+IIF+DE+D+I R
Sbjct: 730 IMSKLAGESESNLRKAFEEAEKNAPAIIFIDELDAIAPKR 611
Score = 48.1 bits (113), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 20/47 (42%), Positives = 33/47 (70%)
Frame = -3
Query: 142 KVPDSTYEMIGGLDKQIKEIKEVIELPVKHPELFEALGIAQPKGVLL 188
+VP+ ++E +GGL+ KE++E+++ PV+HPE F G+ KGVL
Sbjct: 143 EVPNVSWEDVGGLENVKKELQELVQYPVEHPEKFLKFGMTPSKGVLF 3
>25671
Length = 441
Score = 84.0 bits (206), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 54/111 (48%), Positives = 65/111 (58%), Gaps = 8/111 (7%)
Frame = +2
Query: 194 TGKTLLARAVAHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMAREHAPSIIFMDEIDS 253
TGKT+LA+AVA TF VS S L K+ GE ++VR LF MA +APS IF+DEIDS
Sbjct: 2 TGKTMLAKAVATECGTTFFNVSTSSLANKYRGESEKLVRLLFEMAHFYAPSTIFIDEIDS 181
Query: 254 IGSSRLEGGSGGDSE---VQRTMLELLNQLDGFEAT-----KNIKVIMATN 296
I S R G DSE +R ELL Q+DG T K + V+ ATN
Sbjct: 182 ICSKR-----GSDSEHEASRRVKSELLVQMDGVGVTNDDPSKAVMVLAATN 319
>02194
Length = 1891
Score = 67.0 bits (162), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 52/151 (34%), Positives = 72/151 (47%), Gaps = 8/151 (5%)
Frame = -1
Query: 172 PELFEALGIAQPKGVLLYGPPGTGKTLLARAVAHHTDCTFIRVSGSELVQKFIGEGARMV 231
P + GI +G LLYGPPG GK+ A+A D ++ SE G +
Sbjct: 1531 PRWYMDRGIPYRRGYLLYGPPGCGKSSYIMALAGALDYNICVLNLSE-----KGLSDDRL 1367
Query: 232 RELFVMAREHAPSIIFMDEIDSIGSSR--------LEGGSGGDSEVQRTMLELLNQLDGF 283
L +A E SII ++++D+ SR + G G + T LLN LDG
Sbjct: 1366 NHLLTVAPEQ--SIILLEDVDAAFLSRDLSKENPAMYQGMG-----RLTFSGLLNALDGV 1208
Query: 284 EATKNIKVIMATNRIDILDSALLRPGRIDRK 314
+ + V M TN +D LD AL+RPGR+D K
Sbjct: 1207 ASAEARIVFMTTNYLDRLDPALIRPGRVDMK 1115
>17843
Length = 772
Score = 62.4 bits (150), Expect = 3e-10, Method: Compositional matrix adjust.
Identities = 46/173 (26%), Positives = 81/173 (46%), Gaps = 15/173 (8%)
Frame = +1
Query: 180 IAQPKGVLLYGPPGTGKTLLARAVA--------HHTDC-TFIRVSGSELVQKFIGEGARM 230
I+ + +LL+GPPGTGKT L +A+A H C + ++ L K+ E ++
Sbjct: 175 ISWNRVILLHGPPGTGKTTLCKALAHKLCIRLSHRFSCGQLVEINSHSLFSKWFSESGKL 354
Query: 231 VRELF-----VMAREHAPSIIFMDEIDSIGSSRLEGGSGGD-SEVQRTMLELLNQLDGFE 284
V ++F M + +DE++S+ ++R +G + S+ R + +L Q+D +
Sbjct: 355 VTKMFQRLHDYMVDPELLVCVLIDEVESLTAARKSCLNGNEPSDAIRVVNAVLTQIDQLK 534
Query: 285 ATKNIKVIMATNRIDILDSALLRPGRIDRKIEFPPPNEEARLDILKIHSRKMN 337
N ++ +N +D A + R D K PP A I KI+ +N
Sbjct: 535 KFANCLILTTSNITGAIDLAFV--DRADIKQYIGPPTPPA---IYKIYLSCLN 678
>26887
Length = 410
Score = 51.2 bits (121), Expect = 7e-07, Method: Compositional matrix adjust.
Identities = 23/38 (60%), Positives = 30/38 (78%)
Frame = -3
Query: 258 RLEGGSGGDSEVQRTMLELLNQLDGFEATKNIKVIMAT 295
R E SGG+ E+QRTMLELLNQLDGF++ ++KV + T
Sbjct: 168 RYESNSGGEREIQRTMLELLNQLDGFDSRGDVKVHLXT 55
>06766
Length = 976
Score = 44.7 bits (104), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 23/64 (35%), Positives = 40/64 (62%)
Frame = +2
Query: 310 RIDRKIEFPPPNEEARLDILKIHSRKMNLTRGINLRKIAELMPGASGAEVKGVCTEAGMY 369
R+D+ I P P++++R ILK + RK L + ++L IA++ G SGA++ +C A
Sbjct: 2 RLDQLIYIPLPDDKSREAILKANLRKSPLAKEVDLTYIAKVTQGFSGADLTEICQRACKL 181
Query: 370 ALRE 373
A+R+
Sbjct: 182 AIRQ 193
>19561
Length = 474
Score = 43.5 bits (101), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 30/94 (31%), Positives = 43/94 (45%), Gaps = 12/94 (12%)
Frame = -1
Query: 184 KGVLLYGPPGTGKTLLARAVAHHTDCTFIRVSGSE--LVQKFIGEGARMVRELFVMAREH 241
K LL GPPG GKT LA VA H + ++ S+ V+ F + + VM +
Sbjct: 378 KVALLCGPPGLGKTTLAHIVAKHAGYNVVEMNASDDRSVEVFSNKIEAATQMRAVMGADP 199
Query: 242 APSIIFMDEIDSIGSS----------RLEGGSGG 265
P+ + +DEID + R E G+GG
Sbjct: 198 RPNCLIIDEIDGAPQAAVNVLLNILKRPEAGAGG 97
>14413
Length = 826
Score = 43.5 bits (101), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 33/132 (25%), Positives = 57/132 (43%), Gaps = 10/132 (7%)
Frame = +2
Query: 199 LARAVAHHTDCTF-----IRVSGSELVQKFIGEGARMVRELFVMAREHAPS-----IIFM 248
LA +A T +F + ++ L K+ E ++V LF E A + +
Sbjct: 23 LAEKLAIRTQNSFAYTHLVEINSHSLFSKWFSESGKLVARLFGKIGELATDKNNLVCVLI 202
Query: 249 DEIDSIGSSRLEGGSGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDILDSALLRP 308
DE++S+ +R S + R + +L QLD +A N+ ++ +N +D A L
Sbjct: 203 DEVESLAYARSAMSSNEPRDAMRVVNAVLTQLDEIKACPNVLILATSNLAQSIDLAFLDR 382
Query: 309 GRIDRKIEFPPP 320
I + I P P
Sbjct: 383 ADIRQFIGLPDP 418
>01279
Length = 2183
Score = 34.3 bits (77), Expect = 0.086, Method: Compositional matrix adjust.
Identities = 18/38 (47%), Positives = 23/38 (60%), Gaps = 2/38 (5%)
Frame = -3
Query: 184 KGVLLYGPPGTGKTLLARAVAHH--TDCTFIRVSGSEL 219
+ VLL GPPGTGKT +A A+A F + GSE+
Sbjct: 1914 RAVLLAGPPGTGKTAIALAIAQELGNKVPFCPMVGSEV 1801
>37695
Length = 156
Score = 33.9 bits (76), Expect = 0.12, Method: Composition-based stats.
Identities = 15/25 (60%), Positives = 19/25 (76%)
Frame = +3
Query: 363 CTEAGMYALRERRVHVTQEDFEMAV 387
CTEAGM+A+R RR T++DF AV
Sbjct: 9 CTEAGMFAIRARRKMATEKDFLDAV 83
>05247
Length = 375
Score = 32.0 bits (71), Expect = 0.47, Method: Composition-based stats.
Identities = 13/26 (50%), Positives = 17/26 (65%)
Frame = +2
Query: 310 RIDRKIEFPPPNEEARLDILKIHSRK 335
R+DR I PPP+ + RL IH+RK
Sbjct: 2 RMDRLIYVPPPDVQGRLQSFTIHTRK 79
>02744
Length = 3030
Score = 30.8 bits (68), Expect = 0.94, Method: Compositional matrix adjust.
Identities = 20/56 (35%), Positives = 30/56 (53%), Gaps = 3/56 (5%)
Frame = +1
Query: 190 GPPGTGKTLLARAVAHHTD---CTFIRVSGSELVQKFIGEGARMVRELFVMAREHA 242
G G G+ + + HHT TF + ELVQ+ + E +V+ LF +A+EHA
Sbjct: 2767 GAEGRGRDSQSHCLGHHTTPRLLTFDNLLFEELVQQKVAEVRIIVKGLFDVAQEHA 2934
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000364970 | hsapiens_gene_ensembl | 26S protease
regulatory subunit 8 (Proteasome 26S subunit ATPase 5) (Proteasome
subunit p45) (p45/SUG) (Thyroid hormone receptor- interacting protein
1) (TRIP1). [Source:Uniprot/SWISSPROT;Acc:P62195]
(402 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
19129 546 e-156
07243 316 1e-86
23766 271 1e-84
01642 285 2e-77
07247 237 2e-74
02582 178 4e-45
12235 160 9e-40
03022 150 7e-37
26408 122 2e-28
00810 107 1e-23
20270 103 1e-22
38672 83 3e-21
25671 84 1e-16
02194 67 1e-11
17843 62 3e-10
26887 51 7e-07
06766 45 6e-05
19561 44 1e-04
14413 44 1e-04
01279 35 0.072
37695 34 0.12
05247 32 0.45
02744 31 0.95
27434 28 9.2
>19129
Length = 1020
Score = 546 bits (1406), Expect = e-156, Method: Compositional matrix adjust.
Identities = 270/320 (84%), Positives = 283/320 (88%), Gaps = 1/320 (0%)
Frame = +1
Query: 4 EMELEEGKAG-SGLRQYYLSKIEELQLIVNDKSQNLRRLQAQRNELNAKVXXXXXXXXXX 62
+ME+E G G++QYY+SKIEE QLIVN+K+QNLRRL+AQRNELNAKV
Sbjct: 61 QMEIEGAPVGHEGIKQYYISKIEEQQLIVNEKTQNLRRLEAQRNELNAKVRMLREELQLL 240
Query: 63 XXXGSYVGEVVRAMDKKKVLVKVHPEGKFXXXXXXXXXXXXXTPNCRVALRNDSYTLHKI 122
GSYVGEVV+ MDKKKVLVKVHPEGKF TPNCRVALRNDSY LHKI
Sbjct: 241 QEQGSYVGEVVKPMDKKKVLVKVHPEGKFVVDIDKNIDMNSVTPNCRVALRNDSYVLHKI 420
Query: 123 LPNKVDPLVSLMMVEKVPDSTYEMIGGLDKQIKEIKEVIELPVKHPELFEALGIAQPKGV 182
LPNKVDPLVSLMMVEKVPDSTYEM+GGLDKQIKEIKEVIELPVKHPELFEALGIAQPKGV
Sbjct: 421 LPNKVDPLVSLMMVEKVPDSTYEMVGGLDKQIKEIKEVIELPVKHPELFEALGIAQPKGV 600
Query: 183 LLYGPPGTGKTLLARAVAHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMAREHAPSII 242
LLYGPPGTGKTLLARAVAHHT+CTFIRVSGSELVQKFIGEG+RMVRELFVMAREHAPSII
Sbjct: 601 LLYGPPGTGKTLLARAVAHHTECTFIRVSGSELVQKFIGEGSRMVRELFVMAREHAPSII 780
Query: 243 FMDEIDSIGSSRLEGGSGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDILDSALL 302
FMDEIDSIGSSRLEGGSGGDSEVQRTMLELLNQLDGFE +NIKVIMATNRIDILDSALL
Sbjct: 781 FMDEIDSIGSSRLEGGSGGDSEVQRTMLELLNQLDGFEPKQNIKVIMATNRIDILDSALL 960
Query: 303 RPGRIDRKIEFPPPNEEARL 322
RPGRIDRKIEFPPPNEEARL
Sbjct: 961 RPGRIDRKIEFPPPNEEARL 1020
>07243
Length = 1112
Score = 316 bits (809), Expect = 1e-86, Method: Compositional matrix adjust.
Identities = 157/278 (56%), Positives = 201/278 (72%)
Frame = +1
Query: 109 RVALRNDSYTLHKILPNKVDPLVSLMMVEKVPDSTYEMIGGLDKQIKEIKEVIELPVKHP 168
RVAL + T+ + LP +VDPLV M E D TY IGGL +QI+E++EVIELP+ +P
Sbjct: 97 RVALDMTTLTIMRYLPREVDPLVYNMSHEDPGDVTYSAIGGLTEQIRELREVIELPLLNP 276
Query: 169 ELFEALGIAQPKGVLLYGPPGTGKTLLARAVAHHTDCTFIRVSGSELVQKFIGEGARMVR 228
ELF +GI PKG LLYGPPGTGKTLLARAVA D F++V S +V K+IGE AR++R
Sbjct: 277 ELFLRVGITPPKGCLLYGPPGTGKTLLARAVASQLDANFLKVVSSAIVDKYIGESARLIR 456
Query: 229 ELFVMAREHAPSIIFMDEIDSIGSSRLEGGSGGDSEVQRTMLELLNQLDGFEATKNIKVI 288
E+F AR+H P IIFMDEID+IG R G+ D E+QRT++ELLNQ+DGF++ +K+I
Sbjct: 457 EMFNYARDHQPCIIFMDEIDAIGGRRFSEGTSADREIQRTLMELLNQMDGFDSLGQVKMI 636
Query: 289 MATNRIDILDSALLRPGRIDRKIEFPPPNEEARLDILKIHSRKMNLTRGINLRKIAELMP 348
MATNR D LD ALLRPGR+DRKIE P PNE+ARL+ILKIH+ + I+ I +L
Sbjct: 637 MATNRPDTLDPALLRPGRLDRKIEIPLPNEQARLEILKIHALIIAKHGEIDYEAIVKLSD 816
Query: 349 GASGAEVKGVCTEAGMYALRERRVHVTQEDFEMAVAKV 386
+GA+++ VCTEAG++A+R R +V QEDF AV KV
Sbjct: 817 NFNGADLRNVCTEAGLFAIRAEREYVIQEDFMKAVRKV 930
>23766
Length = 1463
Score = 271 bits (692), Expect(2) = 1e-84, Method: Compositional matrix adjust.
Identities = 127/218 (58%), Positives = 166/218 (76%)
Frame = +1
Query: 175 GIAQPKGVLLYGPPGTGKTLLARAVAHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMA 234
G PKGV+LYGPPGTGKTLLA+AVA+ T TF+RV GSEL+QK++G+G ++VRELF +A
Sbjct: 142 GNQAPKGVILYGPPGTGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVA 321
Query: 235 REHAPSIIFMDEIDSIGSSRLEGGSGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRI 294
EHAPSI+F+DEID++G+ R E SGG+ E+QRTMLELLNQLDGF++ ++KVIMATNRI
Sbjct: 322 EEHAPSIVFIDEIDAVGTKRYESNSGGEREIQRTMLELLNQLDGFDSRGDVKVIMATNRI 501
Query: 295 DILDSALLRPGRIDRKIEFPPPNEEARLDILKIHSRKMNLTRGINLRKIAELMPGASGAE 354
+ LD AL+RPGRIDRKIEFP P+E+ + I IH+ +M L +N+ SGA+
Sbjct: 502 ETLDPALIRPGRIDRKIEFPLPDEKTKRRIFTIHTSRMTLAGDVNIDDYVMSKDDLSGAD 681
Query: 355 VKGVCTEAGMYALRERRVHVTQEDFEMAVAKVMQKDSE 392
+K +CTEAG+ ALRERR+ V EDF A V+ + +E
Sbjct: 682 IKAICTEAGLLALRERRMKVRNEDFAKAKENVLYRKNE 795
Score = 60.5 bits (145), Expect(2) = 1e-84, Method: Compositional matrix adjust.
Identities = 29/53 (54%), Positives = 37/53 (69%), Gaps = 1/53 (1%)
Frame = +2
Query: 129 PLVSLMM-VEKVPDSTYEMIGGLDKQIKEIKEVIELPVKHPELFEALGIAQPK 180
P+V++M EK P TY IGGLD QI+EIKE +ELP+ HPE +E +GI K
Sbjct: 2 PMVTVMKGWEKAPQETYADIGGLDTQIQEIKESVELPLTHPEYYEEMGIKHQK 160
>01642
Length = 1406
Score = 285 bits (730), Expect = 2e-77, Method: Compositional matrix adjust.
Identities = 135/267 (50%), Positives = 185/267 (69%)
Frame = -1
Query: 124 PNKVDPLVSLMMVEKVPDSTYEMIGGLDKQIKEIKEVIELPVKHPELFEALGIAQPKGVL 183
P ++ + + + P Y IGG+D Q +E++E +ELP+ H EL++ +GI P+GVL
Sbjct: 1058 PQRLTAVSQCFKLMRSPT*XYSDIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVL 879
Query: 184 LYGPPGTGKTLLARAVAHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMAREHAPSIIF 243
+YGPPG GKT+LA+AVAHHT FIRV GSE VQK++GEG RMVR++F +A+E+AP+IIF
Sbjct: 878 MYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIF 699
Query: 244 MDEIDSIGSSRLEGGSGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDILDSALLR 303
+DEID+I + R + +G D EVQR +LELLNQ+DGF+ T N+KVIMATNR D LD ALLR
Sbjct: 698 IDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQTVNVKVIMATNRADTLDPALLR 519
Query: 304 PGRIDRKIEFPPPNEEARLDILKIHSRKMNLTRGINLRKIAELMPGASGAEVKGVCTEAG 363
PGR+DRKIEFP P+ + I + KMN++ ++L SGA++ +C EAG
Sbjct: 518 PGRLDRKIEFPLPDRRQKRLIFSTITGKMNISEEVDLEDYVARPDKISGADINAICQEAG 339
Query: 364 MYALRERRVHVTQEDFEMAVAKVMQKD 390
M A+RE R V +DFE ++KD
Sbjct: 338 MQAVRENRYVVLAKDFEKGYKNNIKKD 258
>07247
Length = 1753
Score = 237 bits (605), Expect(2) = 2e-74, Method: Compositional matrix adjust.
Identities = 113/199 (56%), Positives = 146/199 (73%)
Frame = -2
Query: 188 PGTGKTLLARAVAHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMAREHAPSIIFMDEI 247
PGTGKTLLARAVA DC F++V S +V K+IGE AR++RE+F AR+H P IIFMDEI
Sbjct: 1407 PGTGKTLLARAVASQLDCNFLKVVSSAIVDKYIGESARLIREMFAFARDHEPCIIFMDEI 1228
Query: 248 DSIGSSRLEGGSGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDILDSALLRPGRI 307
D+IG R G+ D E+QRT++ELLNQ+DGF+A +K+IMATNR D LD ALLRPGR+
Sbjct: 1227 DAIGGRRFSEGTSADREIQRTLMELLNQMDGFDALGQVKMIMATNRPDTLDPALLRPGRL 1048
Query: 308 DRKIEFPPPNEEARLDILKIHSRKMNLTRGINLRKIAELMPGASGAEVKGVCTEAGMYAL 367
DRKIE PNE+ARL+ILKIH+ + I+ + +L +GA+++ VCTEAGM+A+
Sbjct: 1047 DRKIEISLPNEQARLEILKIHANPIAKHGEIDWEAVVKLSEDFNGADLRNVCTEAGMFAI 868
Query: 368 RERRVHVTQEDFEMAVAKV 386
R R +V +EDF AV KV
Sbjct: 867 RAERDYVIEEDFMKAVRKV 811
Score = 60.1 bits (144), Expect(2) = 2e-74, Method: Compositional matrix adjust.
Identities = 29/61 (47%), Positives = 41/61 (67%)
Frame = -1
Query: 127 VDPLVSLMMVEKVPDSTYEMIGGLDKQIKEIKEVIELPVKHPELFEALGIAQPKGVLLYG 186
+DPLV M VE D T+ IGGL +Q++E++EVIELP+ +PELF+ +GI + K
Sbjct: 1588 MDPLVYNMSVEDPGDITFNQIGGLGEQVRELREVIELPLLNPELFQRVGITRLKAACCSD 1409
Query: 187 P 187
P
Sbjct: 1408 P 1406
>02582
Length = 1101
Score = 178 bits (451), Expect = 4e-45, Method: Compositional matrix adjust.
Identities = 106/293 (36%), Positives = 165/293 (56%), Gaps = 34/293 (11%)
Frame = +3
Query: 144 YEMIGGLDKQIKEIKEVIELPVKHPELFEALGIAQPKGVLLYGPPGTGKTLLARAVAHHT 203
+ IGGLD +I++ +E P+ +P+ F+ALG+ KGVLLYGPPG GKT LA+A A
Sbjct: 138 WTDIGGLDLVKLQIRQAVEWPLLYPDTFQALGLPLTKGVLLYGPPGCGKTTLAQAAATAC 317
Query: 204 DCTFIRVSGSELVQKFIGEGARMVRELFVMAREHAPSIIFMDEIDSIGSSRLEGGSGGDS 263
TF+ +S ++L ++G+ + + E F AR APSI+F+DE+D+I R + S G
Sbjct: 318 HVTFLSLSCAQLYSPYVGDAEKKISETFQKARALAPSILFLDEMDAIVGKRSD-SSLGSG 494
Query: 264 EVQRTMLELLNQLDGF-------------------------------EA-TKNIKVIMAT 291
+R + LLN++DG EA +++ V+ AT
Sbjct: 495 VSERVLSALLNEMDGIGVRLDDKSDSREMEIEGSSDHTPQVRQHAVKEAHDRHVLVVAAT 674
Query: 292 NRIDILDSALLRPGRIDRKIEFPPPNEEARLDILKIHSRKMNLTRGINLRKIAELMPGAS 351
NR D+LD ALLRPGR+DR I PPP+ + RL IH+RKM L + ++++++A+L G +
Sbjct: 675 NRPDMLDPALLRPGRMDRLIYVPPPDVQGRLQSFTIHTRKMPLGKDVDVKQLADLTAGYT 854
Query: 352 GAEVKGVCTEAGMYALRERRVH--VTQEDFEMAVAKVMQKDSEKNMSIKKLWK 402
GA++K +C E G+ AL+E V Q+ F A+ S + ++ ++K
Sbjct: 855 GADIKTLCNEVGLLALKESMSAECVNQDHFLNAIKTRKPSLSADSSEVETMYK 1013
>12235
Length = 1749
Score = 160 bits (405), Expect = 9e-40, Method: Compositional matrix adjust.
Identities = 80/183 (43%), Positives = 115/183 (62%), Gaps = 2/183 (1%)
Frame = +1
Query: 207 FIRVSGSELVQKFIGEGARMVRELFVMAREHAPSIIFMDEIDSIGSSRLEGGSGGDSEVQ 266
FI VSGSE ++ F+G G VR++F AR++AP I+F+DEID++G R GG SE +
Sbjct: 16 FITVSGSEFLEMFVGVGPSRVRDMFATARKNAPCILFVDEIDAVGRKRSGRNFGGQSEQE 195
Query: 267 RTMLELLNQLDGFEATKNIKVIMATNRIDILDSALLRPGRIDRKIEFPPPNEEARLDILK 326
T+ +LL ++DGF + V+ ATNR+DILD+ALLRPGR DR+I P P+ + R I K
Sbjct: 196 NTLNQLLVEMDGFNTQTGVVVLAATNRVDILDAALLRPGRFDRQIFVPLPDIKXRASIFK 375
Query: 327 IH--SRKMNLTRGINLRKIAELMPGASGAEVKGVCTEAGMYALRERRVHVTQEDFEMAVA 384
+H K + + RK+A L PG SGA++ VC EA + A R+ + FE A+
Sbjct: 376 VHLDPLKTEVNKNDLARKMAALTPGFSGADIANVCNEAALIAARDLNTSIHMTHFEQAIE 555
Query: 385 KVM 387
+V+
Sbjct: 556 RVV 564
>03022
Length = 2255
Score = 150 bits (380), Expect = 7e-37, Method: Compositional matrix adjust.
Identities = 89/248 (35%), Positives = 140/248 (56%), Gaps = 4/248 (1%)
Frame = +2
Query: 126 KVDPLVSLMMVEKVPDSTYEMIGGLDKQIKEIKEVIELPVKHPELFEALGIAQPKGVLLY 185
K P VP +T+E +G L ++K+ I + PE+ A G+ G++L
Sbjct: 1370 KAQPAAKREGFATVPTTTWEDVGALSNVRAQLKDSILCRIHDPEVSSAFGLPTNSGIILV 1549
Query: 186 GPPGTGKTLLARAVAHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMAREHAPSIIFMD 245
GPPG GKTL+A+A+A+ FI + G EL+ K++GE R +RE F A+ AP +IF D
Sbjct: 1550 GPPGCGKTLVAKAMANEAGLNFIYIKGPELLDKYVGESERNLREKFDKAQACAPCLIFFD 1729
Query: 246 EIDSIGSSRL--EGGSGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDILDSALLR 303
E+D++ S+R +G + G S +LL +DG + V+ ATN I+ +D AL R
Sbjct: 1730 EMDTLCSNRQNNDGSNVGKSVTN----QLLALMDGCGERSQVYVMGATNIIENVDPALQR 1897
Query: 304 PGRIDRKIEFPPPNEEARLDILKIHSRKMNLTR--GINLRKIAELMPGASGAEVKGVCTE 361
PGR DRKI P+ + RLDIL+ ++ + + +++++A+ G SGA++K + E
Sbjct: 1898 PGRFDRKIFIGLPDTDGRLDILRALTKGGSQRKLESCDMQQLAQDTEGFSGADLKHLVNE 2077
Query: 362 AGMYALRE 369
A AL+E
Sbjct: 2078 ASTIALKE 2101
Score = 53.1 bits (126), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 30/116 (25%), Positives = 56/116 (48%), Gaps = 2/116 (1%)
Frame = +1
Query: 138 KVPDSTYEMIGGLDKQIKEIKEVIE--LPVKHPELFEALGIAQPKGVLLYGPPGTGKTLL 195
+P +T + GG +K + E+ E L + + A + LLYGP G+GK L
Sbjct: 508 SIPTATLDDFGGSNKLLAELDSDFEEILYSDYCQYASACDQKACRRYLLYGPRGSGKRFL 687
Query: 196 ARAVAHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMAREHAPSIIFMDEIDSIG 251
A +A ++ + L+ G+ + VR+LF A AP ++++++I+ +
Sbjct: 688 AECIAGQLKLPLLKPKINTLISGVSGDSEQRVRDLFDQAVSQAPCVLYLEDIECLA 855
>26408
Length = 463
Score = 122 bits (307), Expect = 2e-28, Method: Compositional matrix adjust.
Identities = 78/142 (54%), Positives = 87/142 (61%), Gaps = 4/142 (2%)
Frame = +1
Query: 66 GSYVGEVVRAMDKKKVLVKVHPEGKFXXXXXXXX--XXXXXTPNCRVALRNDSYTLHKIL 123
GSYVGEVV+ MDKKKVLVKVHPEGKF CR A R LH
Sbjct: 25 GSYVGEVVKPMDKKKVLVKVHPEGKFVVDFGQEY*YKRCYAQLPCRTAQRK----LHTTQ 192
Query: 124 PNKVDPLVSLMMVEKVPDSTYEMIGG--LDKQIKEIKEVIELPVKHPELFEALGIAQPKG 181
+ + + + + + G L + IKEVIELPVKHPELF+ALGIAQPKG
Sbjct: 193 DLAKQSGSASFVDDGRKSARFNIRNGWWLG*ANQRIKEVIELPVKHPELFDALGIAQPKG 372
Query: 182 VLLYGPPGTGKTLLARAVAHHT 203
VLLYGPPGTGKTLLARAVAHHT
Sbjct: 373 VLLYGPPGTGKTLLARAVAHHT 438
Score = 122 bits (306), Expect = 3e-28, Method: Compositional matrix adjust.
Identities = 62/107 (57%), Positives = 69/107 (64%)
Frame = +2
Query: 105 TPNCRVALRNDSYTLHKILPNKVDPLVSLMMVEKVPDSTYEMIGGLDKQIKEIKEVIELP 164
TPNCRVALRN+SYTLHKILPNKVDPLVSLMMVEKVPDSTYEM+GGLDKQIKE + P
Sbjct: 143 TPNCRVALRNESYTLHKILPNKVDPLVSLMMVEKVPDSTYEMVGGLDKQIKESRR*SNCP 322
Query: 165 VKHPELFEALGIAQPKGVLLYGPPGTGKTLLARAVAHHTDCTFIRVS 211
P + + P K L + +CTFIRVS
Sbjct: 323 SSIPNCSMPWALLSQRVYCCTVRPVLAKRCLPVRLPITPECTFIRVS 463
>00810
Length = 1431
Score = 107 bits (267), Expect = 1e-23, Method: Compositional matrix adjust.
Identities = 72/223 (32%), Positives = 120/223 (53%), Gaps = 3/223 (1%)
Frame = -3
Query: 150 LDKQIKEIKEVIELPVKHPELFEALGIAQP-KGVLLYGPPGTGKTLLARAVAHHTDCTFI 208
L+ I+++KE + LP K +LF + QP KGVLL+GPPG GKT++A+A A FI
Sbjct: 1429 LEDVIQDVKETVILPFKRADLFRHSSLLQPPKGVLLHGPPGCGKTMIAKATAKAAGARFI 1250
Query: 209 RVSGSELVQKFIGEGARMVRELFVMAREHAPSIIFMDEIDSIGSSRLEGGSGGDSEVQRT 268
+ S LV K+ GE + +F +A + P+IIF+DEIDS SR + ++
Sbjct: 1249 NLQVSSLVDKWYGESQKRAEAVFSLAIKLQPTIIFIDEIDSFLRSRTSTDHEATAMIK-- 1076
Query: 269 MLELLNQLDGFEATKNIKVIM--ATNRIDILDSALLRPGRIDRKIEFPPPNEEARLDILK 326
+ ++ DG + +V++ ATNR +D+A+LR I P P + + L
Sbjct: 1075 -TQFMSFWDGLMTDPDCRVMVMGATNRPQDVDAAILRRMPSMFHIGLPGPAQRRSIFNLI 899
Query: 327 IHSRKMNLTRGINLRKIAELMPGASGAEVKGVCTEAGMYALRE 369
+ +++ +N ++AE+ G SG++++ VC A + + E
Sbjct: 898 LSKERID---ALNYDELAEMTDGFSGSDIREVCRAAAVATVHE 779
>20270
Length = 542
Score = 103 bits (256), Expect = 1e-22, Method: Compositional matrix adjust.
Identities = 58/126 (46%), Positives = 80/126 (63%), Gaps = 2/126 (1%)
Frame = -3
Query: 180 KGVLLYGPPGTGKTLLARAVAHH-TDCTFIRVSGSELVQKFIGEGARMVRELFVMAREHA 238
+G+LLYGPPGTGK+ LA+AVA + TF VS S+LV K++GE ++V+ LF +ARE+
Sbjct: 378 RGILLYGPPGTGKSYLAKAVATEANNSTFFSVSSSDLVSKWLGESEKLVKTLFQLARENQ 199
Query: 239 PSIIFMDEIDSIGSSRLEGGSGGDSEVQRTMLELLNQLDGF-EATKNIKVIMATNRIDIL 297
PSIIF+DE+D++ SR E S +R E L Q+ G + V+ ATN L
Sbjct: 198 PSIIFIDEVDALCGSRSENES---ESARRIKTEFLVQMQGVGNDNTGVLVLGATNIPWTL 28
Query: 298 DSALLR 303
DSA+ R
Sbjct: 27 DSAIRR 10
>38672
Length = 730
Score = 82.8 bits (203), Expect(2) = 3e-21, Method: Compositional matrix adjust.
Identities = 46/140 (32%), Positives = 79/140 (56%), Gaps = 18/140 (12%)
Frame = -3
Query: 264 EVQRTML-ELLNQLDGFEATKNIKVIMATNRIDILDSALLRPGRIDRKIEFPPPNEEARL 322
EV+R ++ +LL +DG + ++ V+ ATNR + +D+AL R GR DR+++ P+ RL
Sbjct: 596 EVERRIVSQLLTLMDGLKQRSHVIVMAATNRPNSVDAALRRFGRFDREVDIGIPDATGRL 417
Query: 323 DILKIHSRKMNLTRGINLRKIAELMPGASGAEVKGVCTEAGMYALRER------------ 370
+IL+IH++ M L ++L ++A G GA+V +C+EA + +RE+
Sbjct: 416 EILRIHTKNMKLADDVDLEQVASETHGHVGADVAALCSEAALQQIREKMDLIDLEDDTID 237
Query: 371 -----RVHVTQEDFEMAVAK 385
+ VT +DF A+ K
Sbjct: 236 AEVLDSLAVTMDDFRWALGK 177
Score = 37.0 bits (84), Expect(2) = 3e-21, Method: Compositional matrix adjust.
Identities = 16/40 (40%), Positives = 26/40 (65%)
Frame = -1
Query: 215 LVQKFIGEGARMVRELFVMAREHAPSIIFMDEIDSIGSSR 254
++ K GE +R+ F A ++AP+IIF+DE+D+I R
Sbjct: 730 IMSKLAGESESNLRKAFEEAEKNAPAIIFIDELDAIAPKR 611
Score = 48.1 bits (113), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 20/47 (42%), Positives = 33/47 (70%)
Frame = -3
Query: 138 KVPDSTYEMIGGLDKQIKEIKEVIELPVKHPELFEALGIAQPKGVLL 184
+VP+ ++E +GGL+ KE++E+++ PV+HPE F G+ KGVL
Sbjct: 143 EVPNVSWEDVGGLENVKKELQELVQYPVEHPEKFLKFGMTPSKGVLF 3
>25671
Length = 441
Score = 83.6 bits (205), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 54/111 (48%), Positives = 65/111 (58%), Gaps = 8/111 (7%)
Frame = +2
Query: 190 TGKTLLARAVAHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMAREHAPSIIFMDEIDS 249
TGKT+LA+AVA TF VS S L K+ GE ++VR LF MA +APS IF+DEIDS
Sbjct: 2 TGKTMLAKAVATECGTTFFNVSTSSLANKYRGESEKLVRLLFEMAHFYAPSTIFIDEIDS 181
Query: 250 IGSSRLEGGSGGDSE---VQRTMLELLNQLDGFEAT-----KNIKVIMATN 292
I S R G DSE +R ELL Q+DG T K + V+ ATN
Sbjct: 182 ICSKR-----GSDSEHEASRRVKSELLVQMDGVGVTNDDPSKAVMVLAATN 319
>02194
Length = 1891
Score = 67.0 bits (162), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 52/151 (34%), Positives = 72/151 (47%), Gaps = 8/151 (5%)
Frame = -1
Query: 168 PELFEALGIAQPKGVLLYGPPGTGKTLLARAVAHHTDCTFIRVSGSELVQKFIGEGARMV 227
P + GI +G LLYGPPG GK+ A+A D ++ SE G +
Sbjct: 1531 PRWYMDRGIPYRRGYLLYGPPGCGKSSYIMALAGALDYNICVLNLSE-----KGLSDDRL 1367
Query: 228 RELFVMAREHAPSIIFMDEIDSIGSSR--------LEGGSGGDSEVQRTMLELLNQLDGF 279
L +A E SII ++++D+ SR + G G + T LLN LDG
Sbjct: 1366 NHLLTVAPEQ--SIILLEDVDAAFLSRDLSKENPAMYQGMG-----RLTFSGLLNALDGV 1208
Query: 280 EATKNIKVIMATNRIDILDSALLRPGRIDRK 310
+ + V M TN +D LD AL+RPGR+D K
Sbjct: 1207 ASAEARIVFMTTNYLDRLDPALIRPGRVDMK 1115
>17843
Length = 772
Score = 62.4 bits (150), Expect = 3e-10, Method: Compositional matrix adjust.
Identities = 46/173 (26%), Positives = 81/173 (46%), Gaps = 15/173 (8%)
Frame = +1
Query: 176 IAQPKGVLLYGPPGTGKTLLARAVA--------HHTDC-TFIRVSGSELVQKFIGEGARM 226
I+ + +LL+GPPGTGKT L +A+A H C + ++ L K+ E ++
Sbjct: 175 ISWNRVILLHGPPGTGKTTLCKALAHKLCIRLSHRFSCGQLVEINSHSLFSKWFSESGKL 354
Query: 227 VRELF-----VMAREHAPSIIFMDEIDSIGSSRLEGGSGGD-SEVQRTMLELLNQLDGFE 280
V ++F M + +DE++S+ ++R +G + S+ R + +L Q+D +
Sbjct: 355 VTKMFQRLHDYMVDPELLVCVLIDEVESLTAARKSCLNGNEPSDAIRVVNAVLTQIDQLK 534
Query: 281 ATKNIKVIMATNRIDILDSALLRPGRIDRKIEFPPPNEEARLDILKIHSRKMN 333
N ++ +N +D A + R D K PP A I KI+ +N
Sbjct: 535 KFANCLILTTSNITGAIDLAFV--DRADIKQYIGPPTPPA---IYKIYLSCLN 678
>26887
Length = 410
Score = 51.2 bits (121), Expect = 7e-07, Method: Compositional matrix adjust.
Identities = 23/38 (60%), Positives = 30/38 (78%)
Frame = -3
Query: 254 RLEGGSGGDSEVQRTMLELLNQLDGFEATKNIKVIMAT 291
R E SGG+ E+QRTMLELLNQLDGF++ ++KV + T
Sbjct: 168 RYESNSGGEREIQRTMLELLNQLDGFDSRGDVKVHLXT 55
>06766
Length = 976
Score = 44.7 bits (104), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 23/64 (35%), Positives = 40/64 (62%)
Frame = +2
Query: 306 RIDRKIEFPPPNEEARLDILKIHSRKMNLTRGINLRKIAELMPGASGAEVKGVCTEAGMY 365
R+D+ I P P++++R ILK + RK L + ++L IA++ G SGA++ +C A
Sbjct: 2 RLDQLIYIPLPDDKSREAILKANLRKSPLAKEVDLTYIAKVTQGFSGADLTEICQRACKL 181
Query: 366 ALRE 369
A+R+
Sbjct: 182 AIRQ 193
>19561
Length = 474
Score = 43.5 bits (101), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 30/94 (31%), Positives = 43/94 (45%), Gaps = 12/94 (12%)
Frame = -1
Query: 180 KGVLLYGPPGTGKTLLARAVAHHTDCTFIRVSGSE--LVQKFIGEGARMVRELFVMAREH 237
K LL GPPG GKT LA VA H + ++ S+ V+ F + + VM +
Sbjct: 378 KVALLCGPPGLGKTTLAHIVAKHAGYNVVEMNASDDRSVEVFSNKIEAATQMRAVMGADP 199
Query: 238 APSIIFMDEIDSIGSS----------RLEGGSGG 261
P+ + +DEID + R E G+GG
Sbjct: 198 RPNCLIIDEIDGAPQAAVNVLLNILKRPEAGAGG 97
>14413
Length = 826
Score = 43.5 bits (101), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 28/115 (24%), Positives = 50/115 (43%), Gaps = 5/115 (4%)
Frame = +2
Query: 207 FIRVSGSELVQKFIGEGARMVRELFVMAREHAPS-----IIFMDEIDSIGSSRLEGGSGG 261
+ ++ L K+ E ++V LF E A + +DE++S+ +R S
Sbjct: 74 LVEINSHSLFSKWFSESGKLVARLFGKIGELATDKNNLVCVLIDEVESLAYARSAMSSNE 253
Query: 262 DSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDILDSALLRPGRIDRKIEFPPP 316
+ R + +L QLD +A N+ ++ +N +D A L I + I P P
Sbjct: 254 PRDAMRVVNAVLTQLDEIKACPNVLILATSNLAQSIDLAFLDRADIRQFIGLPDP 418
>01279
Length = 2183
Score = 34.7 bits (78), Expect = 0.072, Method: Compositional matrix adjust.
Identities = 18/38 (47%), Positives = 23/38 (60%), Gaps = 2/38 (5%)
Frame = -3
Query: 180 KGVLLYGPPGTGKTLLARAVAHH--TDCTFIRVSGSEL 215
+ VLL GPPGTGKT +A A+A F + GSE+
Sbjct: 1914 RAVLLAGPPGTGKTAIALAIAQELGNKVPFCPMVGSEV 1801
>37695
Length = 156
Score = 33.9 bits (76), Expect = 0.12, Method: Composition-based stats.
Identities = 15/25 (60%), Positives = 19/25 (76%)
Frame = +3
Query: 359 CTEAGMYALRERRVHVTQEDFEMAV 383
CTEAGM+A+R RR T++DF AV
Sbjct: 9 CTEAGMFAIRARRKMATEKDFLDAV 83
>05247
Length = 375
Score = 32.0 bits (71), Expect = 0.45, Method: Composition-based stats.
Identities = 13/26 (50%), Positives = 17/26 (65%)
Frame = +2
Query: 306 RIDRKIEFPPPNEEARLDILKIHSRK 331
R+DR I PPP+ + RL IH+RK
Sbjct: 2 RMDRLIYVPPPDVQGRLQSFTIHTRK 79
>02744
Length = 3030
Score = 30.8 bits (68), Expect = 0.95, Method: Compositional matrix adjust.
Identities = 20/56 (35%), Positives = 30/56 (53%), Gaps = 3/56 (5%)
Frame = +1
Query: 186 GPPGTGKTLLARAVAHHTD---CTFIRVSGSELVQKFIGEGARMVRELFVMAREHA 238
G G G+ + + HHT TF + ELVQ+ + E +V+ LF +A+EHA
Sbjct: 2767 GAEGRGRDSQSHCLGHHTTPRLLTFDNLLFEELVQQKVAEVRIIVKGLFDVAQEHA 2934
>27434
Length = 472
Score = 27.7 bits (60), Expect = 9.2, Method: Compositional matrix adjust.
Identities = 24/88 (27%), Positives = 40/88 (45%), Gaps = 11/88 (12%)
Frame = +2
Query: 177 AQPKGVLLY--GPPGTGKTLLARAVAHHTDCTFIRVSGSELVQK---------FIGEGAR 225
Q KG +L GPPG GKT + R++A F R++ + + +IG
Sbjct: 149 TQLKGPILCFVGPPGVGKTSIGRSIATTLGREFHRIALGGVCDQSDIRGHRRTYIGSMPG 328
Query: 226 MVRELFVMAREHAPSIIFMDEIDSIGSS 253
+ + A + P + +DEID + +S
Sbjct: 329 RIIQGLKSAGTNNP-VFPLDEIDKLSTS 409
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000310129 | hsapiens_gene_ensembl | 26S proteasome
non-ATPase regulatory subunit 2 (26S proteasome regulatory subunit
RPN1) (26S proteasome regulatory subunit S2) (26S proteasome subunit
p97) (Tumor necrosis factor type 1 receptor- associated protein 2)
(55.11 protein). [Source:Uniprot/SWISSPROT;Acc:Q13200]
(908 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
05493 468 e-150
05545 288 e-100
32303 29 0.036
>05493
Length = 1292
Score = 468 bits (1203), Expect(2) = e-150, Method: Compositional matrix adjust.
Identities = 218/337 (64%), Positives = 275/337 (81%)
Frame = -2
Query: 49 DKQLQDELEMLVERLGEKDTSLYRPALEELRRQIRSSTTSMTSVPKPLKFLRPHYGKLKE 108
D+QLQ+EL MLVERL E D LY+ ALE LR IR+STTSMTSVPKPLKFLRPHY +K+
Sbjct: 1165 DRQLQEELTMLVERLQEPDQRLYKAALESLRVLIRASTTSMTSVPKPLKFLRPHYDTMKQ 986
Query: 109 IYENMAPGENKRFAADIISVLAMTMSGERECLKYRLVGSQEELASWGHEYVRHLAGEVAK 168
I+E + E K F ADIISVL MTMS R+ L Y+ GS+EE+ +WGHEYVRHLAG+VA+
Sbjct: 985 IHEKIRDQETKEFCADIISVLGMTMSEGRDSLHYKQQGSKEEIGAWGHEYVRHLAGQVAQ 806
Query: 169 EWQELDDAEKVQREPLLTLVKEIVPYNMAHNAEHEACDLLMEIEQVDMLEKDIDENAYAK 228
EWQ + +K ++ L+ L K+I+PY+M HNAE EACDL+ME+E++D+ + +DE AY++
Sbjct: 805 EWQVTGEDDKEMKDKLIGLAKQIIPYHMHHNAEAEACDLMMEVERLDLAMEYVDEQAYSR 626
Query: 229 VCLYLTSCVNYVPEPENSALLRCALGVFRKFSRFPEALRLALMLNDMELVEDIFTSCKDV 288
VCLYLTSCV YVP+PEN+ALLRCA+ ++RKF +FP+ALR AL LNDM+L+EDIF SCKD+
Sbjct: 625 VCLYLTSCVAYVPDPENTALLRCAVDLYRKFKQFPQALRFALQLNDMKLIEDIFVSCKDL 446
Query: 289 VVQKQMAFMLGRHGVFLELSEDVEEYEDLTEIMSNVQLNSNFLALARELDIMEPKVPDDI 348
V+QKQ+A+MLGR +F+EL++D+EE ++LTEIMSN LN FL+LARELDIMEPKVP+DI
Sbjct: 445 VMQKQLAYMLGRQQIFMELNDDIEESDELTEIMSNAPLNGAFLSLARELDIMEPKVPEDI 266
Query: 349 YKTHLENNRFGGSGSQVDSARMNLASSFVNGFVNAAF 385
YK+HLE NR + +DSAR NLASSFVNGFVNAAF
Sbjct: 265 YKSHLEPNRTALGANNLDSARQNLASSFVNGFVNAAF 155
Score = 84.3 bits (207), Expect(2) = e-150, Method: Composition-based stats.
Identities = 37/45 (82%), Positives = 40/45 (88%)
Frame = -3
Query: 385 FGQDKLLTDDGNKWLYKNKDHGMLSAAASLGMILLWDVDGGLTQI 429
FGQDKLL +DGNKWLYKNK+HGMLSA ASLG+ILLW VD GL QI
Sbjct: 156 FGQDKLLMEDGNKWLYKNKEHGMLSATASLGLILLWXVDXGLIQI 22
>05545
Length = 1952
Score = 288 bits (736), Expect(2) = e-100, Method: Compositional matrix adjust.
Identities = 140/200 (70%), Positives = 159/200 (79%)
Frame = -1
Query: 642 APADMGAHQGVAVLGIALIAMGEEIGAEMALRTFGHLLRYGEPTLRRAVPLALALISVSN 701
A D+ QG+AVLGI LIAMGEEIG+EM+ R+FGHLLRYGE +RRAVPLALALISVSN
Sbjct: 1799 AGPDLSLQQGIAVLGIGLIAMGEEIGSEMSYRSFGHLLRYGELPIRRAVPLALALISVSN 1620
Query: 702 PRLNILDTLSKFSHDADPEVSYNSIFAMGMVGSGTNNXXXXXXXXXXXXYHAKDPNNLFM 761
P+L ILDTLSKFSHD+DPEV++N+I AMG+VG+GTNN YHAKDPNNLF+
Sbjct: 1619 PKLQILDTLSKFSHDSDPEVAHNAIMAMGIVGAGTNNARLAAMLRQLAVYHAKDPNNLFI 1440
Query: 762 VRLAQXXXXXXXXXXXXCPYHSDRQLMSQVAVAGLLTVLVSFLDVRNIILGKSHYVLYGL 821
VRLAQ CP+HSDR LMS VAVAGL+ L+S LDV+N+ILGKSHYVLY L
Sbjct: 1439 VRLAQGLTHLGKGTLTLCPFHSDRTLMSPVAVAGLMATLISCLDVKNLILGKSHYVLYNL 1260
Query: 822 VAAMQPRMLVTFDEELRPLP 841
VAAMQPRMLVTFDEELRPLP
Sbjct: 1259 VAAMQPRMLVTFDEELRPLP 1200
Score = 97.1 bits (240), Expect(2) = e-100, Method: Compositional matrix adjust.
Identities = 43/50 (86%), Positives = 49/50 (98%)
Frame = -2
Query: 858 KPKTITGFQTHTTPVLLAHGERAELATEEFLPVTPILEGFVILRKNPNYD 907
KPKTITGFQTHTTPVLLA+GERAELATEE+L +TPI+EGFVILRKNP+Y+
Sbjct: 1150 KPKTITGFQTHTTPVLLAYGERAELATEEYLTLTPIMEGFVILRKNPDYE 1001
>32303
Length = 1266
Score = 28.9 bits (63), Expect(2) = 0.036, Method: Compositional matrix adjust.
Identities = 19/58 (32%), Positives = 32/58 (55%), Gaps = 1/58 (1%)
Frame = -2
Query: 473 NSNTMRLGSIFGLGLAYAGSNREDVL-TLLLPVMGDSKSSMEVAGVTALACGMIAVGS 529
+++ +R G GLGLA G+ R+D+ L + D + E AG LA G++ +G+
Sbjct: 1079 STDMVRHGGCLGLGLAAMGTARQDIYEQLKFNLYQDDAVTGEAAG---LAMGLVMLGT 915
Score = 26.9 bits (58), Expect(2) = 0.036, Method: Compositional matrix adjust.
Identities = 16/60 (26%), Positives = 25/60 (41%)
Frame = -3
Query: 556 RWLPLGLGLNHLGKGXXXXXXXXXXXVVSEPFRSFANTLVDVCAYAGSGNVLKVQQLLHI 615
R L +G+ L G+ +P +A AY GSGN +++LLH+
Sbjct: 847 RGLAVGIALTMYGRMEEADALVESLTRDKDPILRWAGMYTLAMAYCGSGNNQAIRRLLHV 668
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000350974 | hsapiens_gene_ensembl |
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit (EC
3.1.3.16) (PP-1A). [Source:Uniprot/SWISSPROT;Acc:P62136]
(286 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
01173 522 e-149
06264 517 e-147
08242 262 9e-71
19040 251 3e-67
06084 230 5e-61
18336 155 1e-56
04295 157 5e-39
25536 119 1e-27
21146 64 5e-11
30980 63 1e-10
36367 55 2e-08
18967 54 7e-08
17953 41 6e-04
01222 27 6.6
>01173
Length = 2619
Score = 522 bits (1344), Expect = e-149, Method: Compositional matrix adjust.
Identities = 252/267 (94%), Positives = 256/267 (95%)
Frame = -1
Query: 19 GDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLR 78
GDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLR
Sbjct: 2508 GDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLR 2329
Query: 79 GNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQS 138
GNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAI+DEKIFCCHGGLSPDLQS
Sbjct: 2328 GNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIIDEKIFCCHGGLSPDLQS 2149
Query: 139 MEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLD 198
MEQIRRIMRPTDVPDQGLLCDLLWSDPDK+ GWGENDRGVSFTFGAEVVAKFLHKHDLD
Sbjct: 2148 MEQIRRIMRPTDVPDQGLLCDLLWSDPDKETMGWGENDRGVSFTFGAEVVAKFLHKHDLD 1969
Query: 199 LICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKN 258
LICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADK
Sbjct: 1968 LICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKK 1789
Query: 259 KGKYGQFSGLNPGGRPITPPRNSAKAK 285
K YG GLN GRP+TPPR +AKAK
Sbjct: 1788 KFPYG---GLNQ-GRPVTPPRGNAKAK 1720
>06264
Length = 999
Score = 517 bits (1332), Expect = e-147, Method: Compositional matrix adjust.
Identities = 248/267 (92%), Positives = 254/267 (95%)
Frame = -3
Query: 19 GDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLR 78
GDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRG+QSLETICLLLAYKIKYPENFFLLR
Sbjct: 910 GDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGRQSLETICLLLAYKIKYPENFFLLR 731
Query: 79 GNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQS 138
GNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAI+DEKIFCCHGGLSPDLQS
Sbjct: 730 GNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIIDEKIFCCHGGLSPDLQS 551
Query: 139 MEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLD 198
MEQIRRIMRPTDVPDQGLLCDLLWSDPDK+ GWGE+DRGVSFTFGAEVVAKFLHKHDLD
Sbjct: 550 MEQIRRIMRPTDVPDQGLLCDLLWSDPDKETMGWGESDRGVSFTFGAEVVAKFLHKHDLD 371
Query: 199 LICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKN 258
LICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADK
Sbjct: 370 LICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKK 191
Query: 259 KGKYGQFSGLNPGGRPITPPRNSAKAK 285
K YG S GRP+TPPR +AKAK
Sbjct: 190 KFPYGGLS----XGRPVTPPRGNAKAK 122
>08242
Length = 3368
Score = 262 bits (670), Expect = 9e-71, Method: Compositional matrix adjust.
Identities = 123/238 (51%), Positives = 173/238 (72%), Gaps = 1/238 (0%)
Frame = -1
Query: 19 GDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLR 78
GDIHGQ+YDL LF+ GG P++NYLF+GD+VDRG S+ET LLLA K++YP+ L+R
Sbjct: 3311 GDIHGQFYDLKELFKVGGDVPDTNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIR 3132
Query: 79 GNHECASINRIYGFYDECKRRY-NIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQ 137
GNHE I ++YGFYDEC R+Y +I +W+ T+ F+ L ++AI+D KIFC HGGLSP +Q
Sbjct: 3131 GNHESRQITQVYGFYDECLRKYGSITVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQ 2952
Query: 138 SMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDL 197
+++QIR I R +VP G +CDLLWSDP+ D+QGWG + RG + FG++VV++F + +
Sbjct: 2951 TLDQIRSIDRKQEVPHDGPMCDLLWSDPE-DMQGWGVSPRGAGYLFGSDVVSQFNAANXI 2775
Query: 198 DLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPA 255
DLICRAHQ+V +GY++ ++T++SAPNYC N A++ +DE L F I + A
Sbjct: 2774 DLICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQRDFTIFEAA 2601
>19040
Length = 452
Score = 251 bits (640), Expect = 3e-67, Method: Compositional matrix adjust.
Identities = 116/123 (94%), Positives = 120/123 (97%)
Frame = -3
Query: 19 GDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLR 78
GDIHGQY DLLRLFEYGGFPP +NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLR
Sbjct: 369 GDIHGQYTDLLRLFEYGGFPPAANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLR 190
Query: 79 GNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQS 138
GNHECASINRIYGFYDECKRRYN+KLWKTFTDCFNCLP+AAI+DEKIFCCHGGLSPDLQ
Sbjct: 189 GNHECASINRIYGFYDECKRRYNVKLWKTFTDCFNCLPVAAIIDEKIFCCHGGLSPDLQG 10
Query: 139 MEQ 141
MEQ
Sbjct: 9 MEQ 1
>06084
Length = 1739
Score = 230 bits (587), Expect = 5e-61, Method: Compositional matrix adjust.
Identities = 119/262 (45%), Positives = 165/262 (62%), Gaps = 1/262 (0%)
Frame = -2
Query: 22 HGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNH 81
HGQ+YDL+ LF+ GG P++NY+F+GD+VDRG SLET LLL K K+P+ LLRGNH
Sbjct: 1738 HGQFYDLMELFKTGGEMPDTNYVFMGDFVDRGYFSLETFTLLLTLKAKWPDKIVLLRGNH 1559
Query: 82 ECASINRIYGFYDECKRRY-NIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSME 140
E I +IYGFYDEC+ +Y N W+ F+ L IAAI+DE I C HGGLSPD+++++
Sbjct: 1558 ESRQITQIYGFYDECQTKYGNANAWRYCCRVFDLLTIAAIIDECILCVHGGLSPDIKTID 1379
Query: 141 QIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLI 200
QIR I R ++P +G CDL+WSDP+ DV W + RG + FGA+V A+F+ ++L LI
Sbjct: 1378 QIRTIERNQEIPHKGAFCDLVWSDPE-DVDTWAMSPRGAGWLFGAKVTAEFVASNNLKLI 1202
Query: 201 CRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKG 260
CRAHQ+V +GY++ +LVT++SAPNYC N A++S + ++ K
Sbjct: 1201 CRAHQLVHEGYKYMFDEKLVTVWSAPNYCYRCGNIAAVLSFTDAEHHEAKLFKAV----- 1037
Query: 261 KYGQFSGLNPGGRPITPPRNSA 282
P + PPR
Sbjct: 1036 ---------PDSERVIPPRTQT 998
>18336
Length = 465
Score = 155 bits (393), Expect(3) = 1e-56, Method: Compositional matrix adjust.
Identities = 74/74 (100%), Positives = 74/74 (100%)
Frame = +2
Query: 19 GDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLR 78
GDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLR
Sbjct: 110 GDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLR 289
Query: 79 GNHECASINRIYGF 92
GNHECASINRIYGF
Sbjct: 290 GNHECASINRIYGF 331
Score = 73.9 bits (180), Expect(3) = 1e-56, Method: Compositional matrix adjust.
Identities = 32/34 (94%), Positives = 33/34 (97%)
Frame = +1
Query: 93 YDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIF 126
YDECKRRYNIKLWKTFTDCFNCLPIAAI+D KIF
Sbjct: 331 YDECKRRYNIKLWKTFTDCFNCLPIAAIIDVKIF 432
Score = 28.9 bits (63), Expect(3) = 1e-56, Method: Compositional matrix adjust.
Identities = 11/12 (91%), Positives = 11/12 (91%)
Frame = +3
Query: 126 FCCHGGLSPDLQ 137
CCHGGLSPDLQ
Sbjct: 429 LCCHGGLSPDLQ 464
>04295
Length = 748
Score = 157 bits (397), Expect = 5e-39, Method: Compositional matrix adjust.
Identities = 78/95 (82%), Positives = 86/95 (90%)
Frame = -1
Query: 185 AEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDET 244
+VV+KFL++HDLDLI RAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAG MMSVDET
Sbjct: 748 GDVVSKFLNRHDLDLITRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDET 569
Query: 245 LMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPR 279
LMCSFQILKP++K K KY Q+ GLN GRPITPP+
Sbjct: 568 LMCSFQILKPSEK-KAKY-QYGGLN-SGRPITPPK 473
>25536
Length = 486
Score = 119 bits (299), Expect = 1e-27, Method: Compositional matrix adjust.
Identities = 52/93 (55%), Positives = 71/93 (76%), Gaps = 1/93 (1%)
Frame = +1
Query: 19 GDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLR 78
GD+HGQ++DL+ LF GG P++NYLF+GDYVDRG S+ET+ LL+A K+++ + +LR
Sbjct: 208 GDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVSLLVALKVRFRDRITILR 387
Query: 79 GNHECASINRIYGFYDECKRRY-NIKLWKTFTD 110
GNHE I ++YGFYDEC R+Y N +WK FTD
Sbjct: 388 GNHESRQITQVYGFYDECLRKYGNANVWKYFTD 486
>21146
Length = 408
Score = 64.3 bits (155), Expect = 5e-11, Method: Compositional matrix adjust.
Identities = 37/78 (47%), Positives = 46/78 (58%), Gaps = 3/78 (3%)
Frame = +3
Query: 154 QGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQ-VVEDGYE 212
QG +CDLLWSDPD D GWG + RG +TFG ++ F H + L LI RAHQ V+E +
Sbjct: 114 QGPMCDLLWSDPD-DRGGWGISPRGAGYTFGQDISETFNHSNGLTLISRAHQLVMEVMFW 290
Query: 213 FFAKRQLVTLF--SAPNY 228
F Q L+ S NY
Sbjct: 291 FVTGMQTCLLYELSLQNY 344
>30980
Length = 765
Score = 63.2 bits (152), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 31/68 (45%), Positives = 41/68 (60%)
Frame = +3
Query: 190 KFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSF 249
F H + L LI RAHQ+V +GY + R +VT+FSAPNYC N A+M +D+ L SF
Sbjct: 3 TFNHSNGLTLISRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDALKYSF 182
Query: 250 QILKPADK 257
PA +
Sbjct: 183 LQFDPAPR 206
>36367
Length = 827
Score = 55.5 bits (132), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 39/132 (29%), Positives = 66/132 (50%), Gaps = 20/132 (15%)
Frame = +1
Query: 129 HGGL-SPDLQS---MEQIRRIMRPTDVP--DQGLLCDLLWSDPD-------------KDV 169
HGG+ SP+ + +E I +I P P D + ++LWSDP K+
Sbjct: 1 HGGIPSPENEGGGHLEAINKIPVPLSDPEVDSPMAWEILWSDPISVDLVSPEVLKDMKEH 180
Query: 170 QGWGENDR-GVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNY 228
G+ N R G + F + FL ++ L + RAH+V E G++ + +L+T+FS+ Y
Sbjct: 181 HGFTFNSRRGTAHFFSCNALLAFLERNGLSHVIRAHEVQEVGFQVQQQGKLLTVFSSSRY 360
Query: 229 CGEFDNAGAMMS 240
CG + A +++
Sbjct: 361 CGGSNEAACVLA 396
>18967
Length = 440
Score = 53.9 bits (128), Expect = 7e-08, Method: Compositional matrix adjust.
Identities = 23/46 (50%), Positives = 34/46 (73%)
Frame = +2
Query: 197 LDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVD 242
LDLICRAHQ+V +G ++ + +LVT++SAPNYC N A++S +
Sbjct: 2 LDLICRAHQLVNEGIKYMFEGKLVTVWSAPNYCYRCGNVAAILSFE 139
>17953
Length = 626
Score = 40.8 bits (94), Expect = 6e-04, Method: Compositional matrix adjust.
Identities = 20/56 (35%), Positives = 32/56 (57%), Gaps = 6/56 (10%)
Frame = -2
Query: 192 LHKHDLDLICRAHQVVEDGYEFFAKRQ------LVTLFSAPNYCGEFDNAGAMMSV 241
L +++L I RAH+ + GY + K Q L+T+FSAPNY ++N ++S
Sbjct: 625 LQQNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKVQLLST 458
>01222
Length = 744
Score = 27.3 bits (59), Expect = 6.6, Method: Compositional matrix adjust.
Identities = 16/55 (29%), Positives = 27/55 (49%), Gaps = 1/55 (1%)
Frame = -2
Query: 75 FLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLP-IAAIVDEKIFCC 128
F + NH C S ++Y + + NIKLW + C+ + V+E++F C
Sbjct: 707 FTIHSNHICRSRRKLYTEINPQHVKINIKLWHPTQFFYLCIMYVCRRVNEQVFVC 543
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000251413 | hsapiens_gene_ensembl | Tubulin
gamma-1 chain (Gamma-1 tubulin) (Gamma-tubulin complex component 1)
(GCP-1). [Source:Uniprot/SWISSPROT;Acc:P23258]
(451 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
05902 506 e-144
16482 191 4e-49
00276 152 2e-37
12457 135 4e-32
04882 115 3e-26
13181 115 5e-26
06360 97 1e-20
39157 96 4e-20
25015 95 5e-20
03702 85 5e-17
28905 60 2e-09
18832 30 2.0
30297 29 3.1
01993 29 3.9
33626 28 7.5
>05902
Length = 1127
Score = 506 bits (1303), Expect = e-144, Method: Compositional matrix adjust.
Identities = 250/296 (84%), Positives = 272/296 (91%)
Frame = +2
Query: 155 ERLNDRYPKKLVQTYSVFPNQDEMSDVVVQPYNSLLTLKRLTQNADCVVVLDNTALNRIA 214
E+LNDR+PKKL+QTYSVFPN DE+SDVVVQPYNSLLTLKRLTQNADCVVVLDNTALNRIA
Sbjct: 71 EKLNDRFPKKLIQTYSVFPNVDEISDVVVQPYNSLLTLKRLTQNADCVVVLDNTALNRIA 250
Query: 215 TDRLHIQNPSFSQINQLVSTIMSASTTTLRYPGYMNNDLIGLIASLIPTPRLHFLMTGYT 274
DRLHI P+F+Q+NQLVST+MS STTTLRYPGYMNNDLIGLIASLIPTPRLHFLMTGYT
Sbjct: 251 ADRLHIDTPTFAQVNQLVSTVMSTSTTTLRYPGYMNNDLIGLIASLIPTPRLHFLMTGYT 430
Query: 275 PLTTDQSVASVRKTTVLDVMRRLLQPKNVMVSTGRDRQTNHCYIAILNIIQGEVDPTQVH 334
PLTTD VA+VRKTTVLDVMRRLLQPKN+MVST RQ NHCYI+ILNIIQGEVDPTQVH
Sbjct: 431 PLTTDSQVANVRKTTVLDVMRRLLQPKNMMVSTPVHRQANHCYISILNIIQGEVDPTQVH 610
Query: 335 KSLQRIRERKLANFIPWGPASIQVALSRKSPYLPSAHRVSGLMMANHTSISSLFERTCRQ 394
KSLQRIRERKLA FIPWGPASIQVALSRKSPY+ +AHRVSGLM+ANHTSIS LFER RQ
Sbjct: 611 KSLQRIRERKLAQFIPWGPASIQVALSRKSPYVQTAHRVSGLMLANHTSISHLFERILRQ 790
Query: 395 YDKLRKREAFLEQFRKEDMFKDNFDEMDTSREIVQQLIDEYHAATRPDYISWGTQE 450
YDKLRKREAF++QF+KE +FKDN DE D SRE +Q L+DEY AATR DY+SWGTQ+
Sbjct: 791 YDKLRKREAFMDQFKKEAIFKDNLDEFDNSREALQLLVDEYQAATRRDYLSWGTQQ 958
>16482
Length = 837
Score = 191 bits (486), Expect = 4e-49, Method: Compositional matrix adjust.
Identities = 91/248 (36%), Positives = 148/248 (59%), Gaps = 1/248 (0%)
Frame = +1
Query: 3 REIITLQLGQCGNQIGFEFWKQLCAEHGISPEGIVEEFATEGTDRKDVFFYQADDEHYIP 62
REI+ +Q GQCGNQIG +FW+ + EHGI P G + +R +V++ +A Y+P
Sbjct: 103 REIVHMQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGKYVP 282
Query: 63 RAVLLDLEPRVIHSILNSPYAKLYNPENIYLSEHGGGAGNNWASG-FSQGEKIHEDIFDI 121
RAVL+DLEP + S+ + P+ +++ P+N + GAGNNWA G +++G ++ + + D+
Sbjct: 283 RAVLVDLEPGTMDSVRSGPFGQIFRPDNFVFGQ--SGAGNNWAKGHYTEGAELVDSVLDV 456
Query: 122 IDREADGSDSLEGFVLCHXXXXXXXXXXXXXXXERLNDRYPKKLVQTYSVFPNQDEMSDV 181
+ +EA+ D L+GF L H ++ + YP +++ T+SV P+ ++SD
Sbjct: 457 VRKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSP-KVSDT 633
Query: 182 VVQPYNSLLTLKRLTQNADCVVVLDNTALNRIATDRLHIQNPSFSQINQLVSTIMSASTT 241
VV+PYN+ L++ +L +N D +DN AL I L + P++ +N LVS MS TT
Sbjct: 634 VVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTT 813
Query: 242 TLRYPGYM 249
LR+PG +
Sbjct: 814 CLRFPGQL 837
>00276
Length = 1330
Score = 152 bits (385), Expect = 2e-37, Method: Compositional matrix adjust.
Identities = 92/342 (26%), Positives = 176/342 (51%), Gaps = 6/342 (1%)
Frame = -3
Query: 100 AGNNWASG-FSQGEKIHEDIFDIIDREADGSDSLEGFVLCHXXXXXXXXXXXXXXXERLN 158
A NN+A G ++ G+++ + + D I + AD L+GF++ H ERL+
Sbjct: 1274 AANNYARGHYTIGKELVDLVLDRIRKLADQCTGLQGFLIFHSFGGGTGSGFTSLXMERLS 1095
Query: 159 DRYPKKLVQTYSVFPNQDEMSDVVVQPYNSLLTLKRLTQNADCVVVLDNTALNRIATDRL 218
Y KK + ++P ++S VV+PYNS+LT +++DC ++DN A+ I L
Sbjct: 1094 VDYGKKSKLEFXIYP-APQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNL 918
Query: 219 HIQNPSFSQINQLVSTIMSASTTTLRYPGYMNNDLIGLIASLIPTPRLHFLMTGYTPLTT 278
I+ P+++ +N+L+ I+S+ T +LR+ G +N DL +L+P PR+HF + Y P+ +
Sbjct: 917 DIERPTYTNLNRLIXQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVIS 738
Query: 279 DQSVASVRKTTVLDVMRRLLQPKNVMVSTGRDRQTNHCYIAILNIIQGEVDPTQVHKSLQ 338
+ A + V ++ +P N +V Y+A + +G+V P V+ ++
Sbjct: 737 AEK-AYHEQLXVAEITNACFEPANQLVKCDPRHGK---YMACCMLYRGDVVPKDVNAAIA 570
Query: 339 RIRERKLANFIPWGPASIQVALSRKSPYLPSAHRVSGL-----MMANHTSISSLFERTCR 393
I+ ++ F+ W P +V ++ + P + ++ + M++N T+I+ + R
Sbjct: 569 TIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDH 390
Query: 394 QYDKLRKREAFLEQFRKEDMFKDNFDEMDTSREIVQQLIDEY 435
++D + + AF+ + E M + F E +RE + L +Y
Sbjct: 389 KFDLMYAKRAFVHWYVGEGMEEGEFSE---AREDLAALEKDY 273
>12457
Length = 781
Score = 135 bits (340), Expect = 4e-32, Method: Compositional matrix adjust.
Identities = 76/241 (31%), Positives = 133/241 (55%), Gaps = 1/241 (0%)
Frame = -1
Query: 66 LLDLEPRVIHSILNSPYAKLYNPENIYLSEHGGGAGNNWASG-FSQGEKIHEDIFDIIDR 124
L+DLEP V+ + Y +L++PE + + A NN+A G ++ G++I + + D I +
Sbjct: 718 LVDLEPTVVDEVRTGTYRQLFHPEQLVTGKED--AANNYARGHYTIGKEIVDLVLDRIRK 545
Query: 125 EADGSDSLEGFVLCHXXXXXXXXXXXXXXXERLNDRYPKKLVQTYSVFPNQDEMSDVVVQ 184
AD L+GF++ H ERL+ Y KK ++++P ++S VV+
Sbjct: 544 LADQCTGLQGFLIFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFAIYP-APQVSTAVVE 368
Query: 185 PYNSLLTLKRLTQNADCVVVLDNTALNRIATDRLHIQNPSFSQINQLVSTIMSASTTTLR 244
PYNS+LT +++DC ++DN A+ I L I+ P+++ +N+L+ I+S+ T +LR
Sbjct: 367 PYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLR 188
Query: 245 YPGYMNNDLIGLIASLIPTPRLHFLMTGYTPLTTDQSVASVRKTTVLDVMRRLLQPKNVM 304
+ G +N DL +L+P PR+HF + Y P+ + + A + TV ++ +P N M
Sbjct: 187 FDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEK-AYHEQLTVAEITNACFEPANQM 11
Query: 305 V 305
V
Sbjct: 10 V 8
>04882
Length = 1136
Score = 115 bits (288), Expect = 3e-26, Method: Compositional matrix adjust.
Identities = 65/221 (29%), Positives = 115/221 (52%), Gaps = 4/221 (1%)
Frame = +2
Query: 220 IQNPSFSQINQLVSTIMSASTTTLRYPGYMNNDLIGLIASLIPTPRLHFLMTGYTPLTTD 279
+ P++ +N LVS MS TT LR+PG +N DL L +++P PRLHF M G+ PLT+
Sbjct: 314 VHTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSR 493
Query: 280 QSVASVRKTTVLDVMRRLLQPKNVMVST----GRDRQTNHCYIAILNIIQGEVDPTQVHK 335
S R TV ++ +++ KN+M + GR Y+ + I +G + +V +
Sbjct: 494 GS-QQYRALTVPELTQQMFDSKNMMAACDPRHGR-------YLTVAAIFRGRMSMKEVDE 649
Query: 336 SLQRIRERKLANFIPWGPASIQVALSRKSPYLPSAHRVSGLMMANHTSISSLFERTCRQY 395
+ ++ + + F+ W P +++ A+ P ++S + N T+I LF+R Q+
Sbjct: 650 QMLNVQNKNSSYFVEWIPNNVKTAVCDIP---PRGLKMSATFIGNSTAIQELFKRISEQF 820
Query: 396 DKLRKREAFLEQFRKEDMFKDNFDEMDTSREIVQQLIDEYH 436
+ +R+AFL + E M + F E +++ + L+ EY
Sbjct: 821 TAMFRRKAFLHWYTGEGMDEMEFTEAESN---MNDLVSEYQ 934
>13181
Length = 1092
Score = 115 bits (287), Expect = 5e-26, Method: Compositional matrix adjust.
Identities = 65/223 (29%), Positives = 116/223 (52%), Gaps = 4/223 (1%)
Frame = -3
Query: 218 LHIQNPSFSQINQLVSTIMSASTTTLRYPGYMNNDLIGLIASLIPTPRLHFLMTGYTPLT 277
L + P++ +N LVS MS TT LR+PG +N DL L +++P PRLHF M G+ PLT
Sbjct: 1069 LKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLT 890
Query: 278 TDQSVASVRKTTVLDVMRRLLQPKNVMVST----GRDRQTNHCYIAILNIIQGEVDPTQV 333
+ S R TV ++ +++ KN+M + GR Y+ + + +G + +V
Sbjct: 889 SRGS-QQYRALTVPELTQQMFDAKNMMAACDPRHGR-------YLTVAAMFRGRMSMKEV 734
Query: 334 HKSLQRIRERKLANFIPWGPASIQVALSRKSPYLPSAHRVSGLMMANHTSISSLFERTCR 393
+ + ++ + + F+ W P +++ A+ P ++S + N T+I LF+R
Sbjct: 733 DEQMLNVQNKNSSYFVEWIPNNVKTAVCDIP---PRGLKMSATFVGNSTAIQELFKRISE 563
Query: 394 QYDKLRKREAFLEQFRKEDMFKDNFDEMDTSREIVQQLIDEYH 436
Q+ + +R+AFL + E M + F E +++ + L+ EY
Sbjct: 562 QFTAMFRRKAFLHWYTGEGMDEMEFTEAESN---MNDLVSEYQ 443
>06360
Length = 1896
Score = 97.4 bits (241), Expect = 1e-20, Method: Compositional matrix adjust.
Identities = 56/174 (32%), Positives = 91/174 (52%), Gaps = 3/174 (1%)
Frame = -1
Query: 3 REIITLQLGQCGNQIGFEFWKQLCAEHGISPEGIVEEFAT--EGTDRKDVFFYQADDEHY 60
RE I++ +GQ G Q+G W+ C EHGI P+G + T G D + FF + +
Sbjct: 1707 RECISVHVGQAGVQMGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKH 1528
Query: 61 IPRAVLLDLEPRVIHSILNSPYAKLYNPENIYLSEHGGGAGNNWASG-FSQGEKIHEDIF 119
+PRAV +DLEP V+ + Y +L++PE + + A NN+A G ++ G++I + +
Sbjct: 1527 VPRAVFVDLEPTVVDEVRTGTYRQLFHPEQLVTGKE--DAANNYARGHYTIGKEIVDLVL 1354
Query: 120 DIIDREADGSDSLEGFVLCHXXXXXXXXXXXXXXXERLNDRYPKKLVQTYSVFP 173
D I + AD L+GF++ H ERL+ Y KK ++++P
Sbjct: 1353 DRIRKLADQCTGLQGFLIFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFAIYP 1192
>39157
Length = 488
Score = 95.5 bits (236), Expect = 4e-20, Method: Compositional matrix adjust.
Identities = 48/128 (37%), Positives = 77/128 (60%), Gaps = 4/128 (3%)
Frame = -1
Query: 3 REIITLQLGQCGNQIGFEFWKQLCAEHGISPEGIVEEFATEGTDRKDVFFYQADDEHYIP 62
REI+ LQ GQCGNQIG +FW+ + EHGI P G + +R +V++ +A Y+P
Sbjct: 440 REIVHLQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGKYVP 261
Query: 63 RAVLLDLEPRVIHSILN-SPYA-KLYNPENIYLSEHGGGAGNNWASGFS--QGEKIHEDI 118
RAVL+DLEP + S+ + SP+ K++ P+N + GAGNNW + +G ++ + +
Sbjct: 260 RAVLVDLEPGTMDSVRSGSPFGPKIFRPDNFVFGQS--GAGNNWGQKDTTQRGAELVDSV 87
Query: 119 FDIIDREA 126
D++ +
Sbjct: 86 LDVVRKRG 63
>25015
Length = 458
Score = 95.1 bits (235), Expect = 5e-20, Method: Compositional matrix adjust.
Identities = 43/120 (35%), Positives = 74/120 (61%), Gaps = 1/120 (0%)
Frame = -3
Query: 21 FWKQLCAEHGISPEGIVEEFATEGTDRKDVFFYQADDEHYIPRAVLLDLEPRVIHSILNS 80
FW+ + EHGI P G + +R +V++ +A Y+PRAVL+DLEP + S+ +
Sbjct: 363 FWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGKYVPRAVLVDLEPGTMDSVRSG 184
Query: 81 PYAKLYNPENIYLSEHGGGAGNNWASG-FSQGEKIHEDIFDIIDREADGSDSLEGFVLCH 139
P+ +++ P+N + GAGNNWA G +++G ++ + + D++ +EA+ D L+GF L H
Sbjct: 183 PFGQIFRPDNFVFGQS--GAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQLTH 10
>03702
Length = 1932
Score = 85.1 bits (209), Expect = 5e-17, Method: Compositional matrix adjust.
Identities = 50/151 (33%), Positives = 83/151 (54%)
Frame = +1
Query: 155 ERLNDRYPKKLVQTYSVFPNQDEMSDVVVQPYNSLLTLKRLTQNADCVVVLDNTALNRIA 214
ERL+ Y KK ++++P ++S VV+PYNS+LT +++DC ++DN A+ I
Sbjct: 1459 ERLSVDYGKKSKLEFAIYP-APQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDIC 1635
Query: 215 TDRLHIQNPSFSQINQLVSTIMSASTTTLRYPGYMNNDLIGLIASLIPTPRLHFLMTGYT 274
L I+ P ++ +N+L+ I+S+ T +LR+ G +N DL +L+PTP H L G+
Sbjct: 1636 RRNLDIERPXYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVPTP--HPLPPGHL 1809
Query: 275 PLTTDQSVASVRKTTVLDVMRRLLQPKNVMV 305
A + TV +V +P N +V
Sbjct: 1810 CPVISAEKAYHEQLTVAEVTNACFEPANQLV 1902
>28905
Length = 425
Score = 59.7 bits (143), Expect = 2e-09, Method: Composition-based stats.
Identities = 36/142 (25%), Positives = 72/142 (50%), Gaps = 5/142 (3%)
Frame = -1
Query: 254 IGLIASLIPTPRLHFLMTGYTPLTTDQSVASVRKTTVLDVMRRLLQPKNVMVST----GR 309
+ + +++P PRLHF M G+ PLT+ S R TV ++ +++ KN+M + GR
Sbjct: 395 VNVAVNMVPFPRLHFFMPGFAPLTSRGS-QQYRALTVPELTQQMFDAKNMMAACDPRHGR 219
Query: 310 DRQTNHCYIAILNIIQGEVDPTQVHKSLQRIRERKLANFIPWGPASIQVALSRKSPYLPS 369
Y+ + + +G + +V + + ++ + + F+ W P +++ A+ P
Sbjct: 218 -------YLTVAAMFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIP---PR 69
Query: 370 AHRVSGLMMANHTSISS-LFER 390
++SG + N T+I LF+R
Sbjct: 68 GLKMSGTFIGNSTAIQGRLFKR 3
>18832
Length = 499
Score = 30.0 bits (66), Expect = 2.0, Method: Compositional matrix adjust.
Identities = 19/71 (26%), Positives = 36/71 (50%), Gaps = 7/71 (9%)
Frame = -2
Query: 20 EFWKQLCAEHGISPEGIVEEFATEGTDRKDVFFYQADDEHYIPRAVLLD-LEPRVIHSI- 77
++W QLCA G+S G + + G R A +++++ +L++ + P +HSI
Sbjct: 465 QWWSQLCAHIGVSSMGQLHQLG--GNART------ACEDYFMTSVLLMNTMSPERVHSIP 310
Query: 78 -----LNSPYA 83
+ SPY+
Sbjct: 309 AQPSPVQSPYS 277
>30297
Length = 822
Score = 29.3 bits (64), Expect = 3.1, Method: Compositional matrix adjust.
Identities = 12/36 (33%), Positives = 20/36 (55%)
Frame = -2
Query: 334 HKSLQRIRERKLANFIPWGPASIQVALSRKSPYLPS 369
H L+R+ R +PWGP+ ++ L+R P P+
Sbjct: 452 HPHLERLPGRPPHGTVPWGPSHLEEWLARWPPTRPT 345
>01993
Length = 1915
Score = 28.9 bits (63), Expect = 3.9, Method: Compositional matrix adjust.
Identities = 12/28 (42%), Positives = 17/28 (60%)
Frame = -3
Query: 295 RRLLQPKNVMVSTGRDRQTNHCYIAILN 322
R +L P +M T R++ TNH +ILN
Sbjct: 341 RHILSPNTIMTKTHRNKVTNHVL*SILN 258
>33626
Length = 391
Score = 28.1 bits (61), Expect = 7.5, Method: Composition-based stats.
Identities = 17/55 (30%), Positives = 31/55 (56%)
Frame = -3
Query: 230 QLVSTIMSASTTTLRYPGYMNNDLIGLIASLIPTPRLHFLMTGYTPLTTDQSVAS 284
++VS +A+ +L + ++NN I +I L+ T R ++GY P TD ++S
Sbjct: 200 RVVSPFAAAARFSLLWFFFLNNLCILIIVFLVATDRNLNNISGYLPHLTDHFLSS 36
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000344456 | hsapiens_gene_ensembl | Catenin beta-1
(Beta-catenin). [Source:Uniprot/SWISSPROT;Acc:P35222]
(781 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
14657 507 e-144
15086 295 5e-80
12505 115 6e-30
38361 107 9e-28
17600 107 2e-23
12579 96 5e-20
36452 46 7e-05
28685 35 0.11
36960 29 6.3
>14657
Length = 918
Score = 507 bits (1305), Expect = e-144, Method: Compositional matrix adjust.
Identities = 251/305 (82%), Positives = 272/305 (89%), Gaps = 1/305 (0%)
Frame = -3
Query: 102 TLDEGMQIPSTQFDAAHPTNVQRLAEPSQMLKHAVVNLINYQDDAELATRAIPELTKLLN 161
TL EG+QIPSTQ PT VQRL+EPSQMLKHAVVNLINYQDDA+LATRAIPEL KLL
Sbjct: 916 TLPEGVQIPSTQVHPDEPTAVQRLSEPSQMLKHAVVNLINYQDDADLATRAIPELIKLLX 737
Query: 162 DEDQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAIVRTMQNTNDVETARCTAGTLHNL 221
DED VVV +AA+MVHQLSKKEASRHAIM SPQM++A++R M NT D+ET RC AGTLHNL
Sbjct: 736 DEDXVVVYQAAMMVHQLSKKEASRHAIMNSPQMIAALIRAMANTEDIETTRCAAGTLHNL 557
Query: 222 SHHREGLLAIFKSGGIPALVKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQK 281
SHHR+GLLAIFKSGGIPALVK+L SP++SVLFYAITTLHNLLLHQEG+KMAVRLAGGLQK
Sbjct: 556 SHHRQGLLAIFKSGGIPALVKLLSSPMESVLFYAITTLHNLLLHQEGSKMAVRLAGGLQK 377
Query: 282 MVALLNK-TNVKFLAITTDCLQILAYGNQESKLIILASGGPQALVNIMRTYTYEKLLWTT 340
MVALL + NVKFLAITTDCLQILAYGNQESKLIILASGGP LV IM++YTYEKLLWTT
Sbjct: 376 MVALLQRNNNVKFLAITTDCLQILAYGNQESKLIILASGGPGELVRIMKSYTYEKLLWTT 197
Query: 341 SRVLKVLSVCSSNKPAIVEAGGMQALGLHLTDPSQRLVQNCLWTLRNLSDAATKQEGMEG 400
SRVLKVLSVC SNKPAIVEAGGMQAL +HL SQRLVQNCLW+LRNLSDAATK + MEG
Sbjct: 196 SRVLKVLSVCPSNKPAIVEAGGMQALAMHLGHQSQRLVQNCLWSLRNLSDAATKMDNMEG 17
Query: 401 LLGTL 405
LL L
Sbjct: 16 LLHML 2
Score = 33.9 bits (76), Expect = 0.27, Method: Compositional matrix adjust.
Identities = 49/177 (27%), Positives = 78/177 (44%), Gaps = 4/177 (2%)
Frame = -3
Query: 370 LTDPSQRLVQNC--LWTLRNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCAAGILSNL 427
L++PSQ L L ++ +D AT+ + L++LL +D VV AA ++ L
Sbjct: 847 LSEPSQMLKHAVVNLINYQDDADLATRA------IPELIKLLXDEDXVVVYQAAMMVHQL 686
Query: 428 TCNNYKNKMMVCQVGGIEALVRTVLRAGDREDITEPAICA--LRHLTSRHQEAEMAQNAV 485
+ ++ I AL+R + + EDI E CA H S H++ +A +
Sbjct: 685 SKKEASRHAIMNSPQMIAALIRAM---ANTEDI-ETTRCAAGTLHNLSHHRQGLLA---I 527
Query: 486 RLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLLVR 542
G+P +VKLL P L A L L + +R G + ++V LL R
Sbjct: 526 FKSGGIPALVKLLSSPMESVLFYAITTLHNLLLHQEGSKMAVRLAGGLQKMVALLQR 356
>15086
Length = 548
Score = 295 bits (755), Expect = 5e-80, Method: Compositional matrix adjust.
Identities = 143/171 (83%), Positives = 159/171 (92%), Gaps = 1/171 (0%)
Frame = +1
Query: 152 AIPELTKLLNDEDQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAIVRTMQNTNDVETA 211
AIPEL KLL+DEDQVVV +AA+MVHQLSKKEASRHAIM SPQM++A++R + T+D+ET
Sbjct: 1 AIPELIKLLSDEDQVVVCQAAMMVHQLSKKEASRHAIMNSPQMIAALIRALATTDDMETT 180
Query: 212 RCTAGTLHNLSHHREGLLAIFKSGGIPALVKMLGSPVDSVLFYAITTLHNLLLHQEGAKM 271
RC AGTLHNLSHHR+GLLAIFKSGGIPALVK+L SPV+SVLFYAITTLHNLLLHQEG+KM
Sbjct: 181 RCAAGTLHNLSHHRQGLLAIFKSGGIPALVKLLSSPVESVLFYAITTLHNLLLHQEGSKM 360
Query: 272 AVRLAGGLQKMVALLNK-TNVKFLAITTDCLQILAYGNQESKLIILASGGP 321
AVR+AGGLQKMVALL + NVKFLAITTDCLQILAYGNQESKLIILASGGP
Sbjct: 361 AVRMAGGLQKMVALLQRNNNVKFLAITTDCLQILAYGNQESKLIILASGGP 513
Score = 31.6 bits (70), Expect = 1.4, Method: Compositional matrix adjust.
Identities = 39/138 (28%), Positives = 61/138 (44%)
Frame = +1
Query: 405 LVQLLGSDDINVVTCAAGILSNLTCNNYKNKMMVCQVGGIEALVRTVLRAGDREDITEPA 464
L++LL +D VV AA ++ L+ ++ I AL+R + D E T A
Sbjct: 13 LIKLLSDEDQVVVCQAAMMVHQLSKKEASRHAIMNSPQMIAALIRALATTDDMET-TRCA 189
Query: 465 ICALRHLTSRHQEAEMAQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANH 524
L +L S H++ +A + G+P +VKLL P L A L L +
Sbjct: 190 AGTLHNL-SHHRQGLLA---IFKSGGIPALVKLLSSPVESVLFYAITTLHNLLLHQEGSK 357
Query: 525 APLREQGAIPRLVQLLVR 542
+R G + ++V LL R
Sbjct: 358 MAVRMAGGLQKMVALLQR 411
>12505
Length = 836
Score = 115 bits (289), Expect(2) = 6e-30, Method: Compositional matrix adjust.
Identities = 57/80 (71%), Positives = 60/80 (75%)
Frame = -3
Query: 592 GLNTIPLFVQLLYSPIENIQRVAAGVLCELAQDKXXXXXXXXXXXXXPLTELLHSRNEGV 651
G+ + + QLLYSPIENIQRVAAGVLCELA DK PLTELLHSRNEGV
Sbjct: 732 GVGAVLRYHQLLYSPIENIQRVAAGVLCELAADKEGAEMIEQEGATAPLTELLHSRNEGV 553
Query: 652 ATYAAAVLFRMSEDKPQDYK 671
TYAAAVLFRMSEDKPQDYK
Sbjct: 552 XTYAAAVLFRMSEDKPQDYK 493
Score = 33.9 bits (76), Expect(2) = 6e-30, Method: Compositional matrix adjust.
Identities = 17/31 (54%), Positives = 23/31 (74%), Gaps = 3/31 (9%)
Frame = -2
Query: 671 KKRLSVELTSSLFRTEPMAWNETA---DLGL 698
+KRLS+ELTSSL+R + M W+E D+GL
Sbjct: 496 QKRLSMELTSSLYRGDNMNWSEPPGFEDVGL 404
Score = 80.9 bits (198), Expect = 2e-15, Method: Composition-based stats.
Identities = 37/44 (84%), Positives = 43/44 (97%)
Frame = -1
Query: 215 AGTLHNLSHHREGLLAIFKSGGIPALVKMLGSPVDSVLFYAITT 258
AGTLHNLSHHR+GLLAIF+SGGIPALVK+L SP++SVLFYAIT+
Sbjct: 833 AGTLHNLSHHRQGLLAIFRSGGIPALVKLLSSPMESVLFYAITS 702
>38361
Length = 227
Score = 107 bits (268), Expect(2) = 9e-28, Method: Compositional matrix adjust.
Identities = 50/63 (79%), Positives = 55/63 (87%)
Frame = -1
Query: 457 REDITEPAICALRHLTSRHQEAEMAQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRN 516
R + ++CALRHLTSRH EAEMAQNAVRLHYGLPV+VKLLHPPS WPLIKA VGL+RN
Sbjct: 191 RTSLNLDSVCALRHLTSRHPEAEMAQNAVRLHYGLPVLVKLLHPPSRWPLIKAVVGLVRN 12
Query: 517 LAL 519
LAL
Sbjct: 11 LAL 3
Score = 34.7 bits (78), Expect(2) = 9e-28, Method: Compositional matrix adjust.
Identities = 14/17 (82%), Positives = 16/17 (94%)
Frame = -3
Query: 447 LVRTVLRAGDREDITEP 463
VRTV++AGDREDITEP
Sbjct: 225 FVRTVMQAGDREDITEP 175
>17600
Length = 752
Score = 107 bits (267), Expect = 2e-23, Method: Compositional matrix adjust.
Identities = 67/135 (49%), Positives = 83/135 (61%), Gaps = 15/135 (11%)
Frame = +1
Query: 639 PLTELLHSRNEGVATYAAAVLFRMSEDKPQDYKKRLSVELTSSLFRTEPMAWNETA---D 695
PLT+LLHSRNEGVATYAAAVLFRMSEDKPQDYKKRLS+ELTSSL+R + M W+E D
Sbjct: 292 PLTDLLHSRNEGVATYAAAVLFRMSEDKPQDYKKRLSMELTSSLYRGDNMNWSEPPGFED 471
Query: 696 LGLDIGAQGEPLGYRQDDPSYRSFHSGGY--------GQDALGMDPMMEHEMGGHHPGA- 746
+GL +P+ +Q P ++ S Y G+ G D + + M G GA
Sbjct: 472 MGLLTDTSRDPMYSQQQLPPHQGSQSSMYSGSQHDMQGRPPTGYDQVPVNSMQGLDLGAA 651
Query: 747 ---DYPVDGLPDLGH 758
P+D +PDLG
Sbjct: 652 GAYGGPLDNIPDLGQ 696
>12579
Length = 1870
Score = 96.3 bits (238), Expect = 5e-20, Method: Compositional matrix adjust.
Identities = 61/123 (49%), Positives = 78/123 (63%), Gaps = 6/123 (4%)
Frame = +2
Query: 10 LDMAMEPDRKAAVSHWQQQSYL-DSGIHSGATTTAPSLSGKGNPEE---EDVDTSQVLYE 65
LDM ++ + WQQ YL DSGIHSGATT APS+S KG+ EE D+D ++ +++
Sbjct: 92 LDMPVD-SKHEQTMMWQQNQYLADSGIHSGATTQAPSISSKGHGEELEEGDMDPTK-MFD 265
Query: 66 WEQGFSQSFTQ--EQVADIDGQYAMTRAQRVRAAMFPETLDEGMQIPSTQFDAAHPTNVQ 123
W G FT EQV +++ Q TR QRVRAA+FPE+L EG+QIPSTQ PT V
Sbjct: 266 W--GLPDPFTPQPEQVEEMNQQLNQTRPQRVRAAIFPESLPEGVQIPSTQVHPDQPTAVX 439
Query: 124 RLA 126
LA
Sbjct: 440 *LA 448
>36452
Length = 607
Score = 45.8 bits (107), Expect = 7e-05, Method: Compositional matrix adjust.
Identities = 44/190 (23%), Positives = 85/190 (44%), Gaps = 5/190 (2%)
Frame = +1
Query: 207 DVETARCTAGTLHNLSHHREGLLAIFKSGGIPALVKMLGSPVDSVLFYAITTLHNLLLHQ 266
DVE ARC A L + S ++ A+ ++G IP L K+L SP + +L + TL +
Sbjct: 7 DVEVARCGALALWSCSKSKKNKEAMQRAGAIPLLAKLLKSPHEDMLIPVVGTLQE-CASE 183
Query: 267 EGAKMAVRLAGGLQKMVALLNKTNVKFLA---ITTDCLQIL--AYGNQESKLIILASGGP 321
++A+R G ++ +V L + A + C + +E++ ++ GG
Sbjct: 184 PSYRLAIRTEGMIEDLVKNLKSSVPDKPANPELQMHCASAIFKCAEEKETRDLVRQYGGL 363
Query: 322 QALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLHLTDPSQRLVQNC 381
LV ++ ++LL + + ++ N E ++ L LT+ + ++ N
Sbjct: 364 DPLVGLLNKMDNKELLAAATGAIWKCAISPENVARFQELKCIELLVALLTNQPEEVLVNV 543
Query: 382 LWTLRNLSDA 391
+ L L+ A
Sbjct: 544 VGALGELAKA 573
Score = 32.0 bits (71), Expect = 0.89, Method: Compositional matrix adjust.
Identities = 56/215 (26%), Positives = 88/215 (40%), Gaps = 5/215 (2%)
Frame = +1
Query: 382 LWTLRNLSDAATKQEGME--GLLGTLVQLLGSDDINVVTCAAGILSNLTCNNYKNKMMVC 439
LW+ S + +E M+ G + L +LL S +++ G L + ++ +
Sbjct: 40 LWSC---SKSKKNKEAMQRAGAIPLLAKLLKSPHEDMLIPVVGTLQECA-SEPSYRLAIR 207
Query: 440 QVGGIEALVRTVLRAGDREDITEPAI---CALRHLTSRHQEAEMAQNAVRLHYGLPVVVK 496
G IE LV+ L++ + P + CA + E + ++ VR + GL +V
Sbjct: 208 TEGMIEDLVKN-LKSSVPDKPANPELQMHCA--SAIFKCAEEKETRDLVRQYGGLDPLVG 378
Query: 497 LLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLLVRAHQDTQRRTSMGGT 556
LL+ + L+ A G I A+ P N A +E I LV LL T
Sbjct: 379 LLNKMDNKELLAAATGAIWKCAISPENVARFQELKCIELLVALL---------------T 513
Query: 557 QQQFVEGVRMEEIVEGCTGALHILARDVHNRIVIR 591
Q EE++ GAL LA+ NR IR
Sbjct: 514 NQP-------EEVLVNVVGALGELAKAQPNRAQIR 597
>28685
Length = 834
Score = 35.0 bits (79), Expect = 0.11, Method: Composition-based stats.
Identities = 19/36 (52%), Positives = 20/36 (55%), Gaps = 7/36 (19%)
Frame = +2
Query: 753 LPDLGHAQDL----MD---GLPPGDSNQLAWFDTDL 781
LPDLG DL +D G PPGD WFDTDL
Sbjct: 23 LPDLGPGSDLNFDSIDPNLGAPPGDGGPSIWFDTDL 130
>36960
Length = 551
Score = 29.3 bits (64), Expect = 6.3, Method: Composition-based stats.
Identities = 16/43 (37%), Positives = 23/43 (53%)
Frame = +3
Query: 231 IFKSGGIPALVKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAV 273
I +GGIP ++ L S + + AITTL L+ Q A + V
Sbjct: 321 IVTNGGIPLVINCLSSCSEETVMSAITTLMYLITPQSQAAITV 449
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000379486 | hsapiens_gene_ensembl | Catenin beta-1
(Beta-catenin). [Source:Uniprot/SWISSPROT;Acc:P35222]
(781 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
14657 507 e-144
15086 295 5e-80
12505 115 6e-30
38361 107 9e-28
17600 107 2e-23
12579 96 5e-20
36452 46 7e-05
28685 35 0.11
36960 29 6.3
>14657
Length = 918
Score = 507 bits (1305), Expect = e-144, Method: Compositional matrix adjust.
Identities = 251/305 (82%), Positives = 272/305 (89%), Gaps = 1/305 (0%)
Frame = -3
Query: 102 TLDEGMQIPSTQFDAAHPTNVQRLAEPSQMLKHAVVNLINYQDDAELATRAIPELTKLLN 161
TL EG+QIPSTQ PT VQRL+EPSQMLKHAVVNLINYQDDA+LATRAIPEL KLL
Sbjct: 916 TLPEGVQIPSTQVHPDEPTAVQRLSEPSQMLKHAVVNLINYQDDADLATRAIPELIKLLX 737
Query: 162 DEDQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAIVRTMQNTNDVETARCTAGTLHNL 221
DED VVV +AA+MVHQLSKKEASRHAIM SPQM++A++R M NT D+ET RC AGTLHNL
Sbjct: 736 DEDXVVVYQAAMMVHQLSKKEASRHAIMNSPQMIAALIRAMANTEDIETTRCAAGTLHNL 557
Query: 222 SHHREGLLAIFKSGGIPALVKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQK 281
SHHR+GLLAIFKSGGIPALVK+L SP++SVLFYAITTLHNLLLHQEG+KMAVRLAGGLQK
Sbjct: 556 SHHRQGLLAIFKSGGIPALVKLLSSPMESVLFYAITTLHNLLLHQEGSKMAVRLAGGLQK 377
Query: 282 MVALLNK-TNVKFLAITTDCLQILAYGNQESKLIILASGGPQALVNIMRTYTYEKLLWTT 340
MVALL + NVKFLAITTDCLQILAYGNQESKLIILASGGP LV IM++YTYEKLLWTT
Sbjct: 376 MVALLQRNNNVKFLAITTDCLQILAYGNQESKLIILASGGPGELVRIMKSYTYEKLLWTT 197
Query: 341 SRVLKVLSVCSSNKPAIVEAGGMQALGLHLTDPSQRLVQNCLWTLRNLSDAATKQEGMEG 400
SRVLKVLSVC SNKPAIVEAGGMQAL +HL SQRLVQNCLW+LRNLSDAATK + MEG
Sbjct: 196 SRVLKVLSVCPSNKPAIVEAGGMQALAMHLGHQSQRLVQNCLWSLRNLSDAATKMDNMEG 17
Query: 401 LLGTL 405
LL L
Sbjct: 16 LLHML 2
Score = 33.9 bits (76), Expect = 0.27, Method: Compositional matrix adjust.
Identities = 49/177 (27%), Positives = 78/177 (44%), Gaps = 4/177 (2%)
Frame = -3
Query: 370 LTDPSQRLVQNC--LWTLRNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCAAGILSNL 427
L++PSQ L L ++ +D AT+ + L++LL +D VV AA ++ L
Sbjct: 847 LSEPSQMLKHAVVNLINYQDDADLATRA------IPELIKLLXDEDXVVVYQAAMMVHQL 686
Query: 428 TCNNYKNKMMVCQVGGIEALVRTVLRAGDREDITEPAICA--LRHLTSRHQEAEMAQNAV 485
+ ++ I AL+R + + EDI E CA H S H++ +A +
Sbjct: 685 SKKEASRHAIMNSPQMIAALIRAM---ANTEDI-ETTRCAAGTLHNLSHHRQGLLA---I 527
Query: 486 RLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLLVR 542
G+P +VKLL P L A L L + +R G + ++V LL R
Sbjct: 526 FKSGGIPALVKLLSSPMESVLFYAITTLHNLLLHQEGSKMAVRLAGGLQKMVALLQR 356
>15086
Length = 548
Score = 295 bits (755), Expect = 5e-80, Method: Compositional matrix adjust.
Identities = 143/171 (83%), Positives = 159/171 (92%), Gaps = 1/171 (0%)
Frame = +1
Query: 152 AIPELTKLLNDEDQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAIVRTMQNTNDVETA 211
AIPEL KLL+DEDQVVV +AA+MVHQLSKKEASRHAIM SPQM++A++R + T+D+ET
Sbjct: 1 AIPELIKLLSDEDQVVVCQAAMMVHQLSKKEASRHAIMNSPQMIAALIRALATTDDMETT 180
Query: 212 RCTAGTLHNLSHHREGLLAIFKSGGIPALVKMLGSPVDSVLFYAITTLHNLLLHQEGAKM 271
RC AGTLHNLSHHR+GLLAIFKSGGIPALVK+L SPV+SVLFYAITTLHNLLLHQEG+KM
Sbjct: 181 RCAAGTLHNLSHHRQGLLAIFKSGGIPALVKLLSSPVESVLFYAITTLHNLLLHQEGSKM 360
Query: 272 AVRLAGGLQKMVALLNK-TNVKFLAITTDCLQILAYGNQESKLIILASGGP 321
AVR+AGGLQKMVALL + NVKFLAITTDCLQILAYGNQESKLIILASGGP
Sbjct: 361 AVRMAGGLQKMVALLQRNNNVKFLAITTDCLQILAYGNQESKLIILASGGP 513
Score = 31.6 bits (70), Expect = 1.4, Method: Compositional matrix adjust.
Identities = 39/138 (28%), Positives = 61/138 (44%)
Frame = +1
Query: 405 LVQLLGSDDINVVTCAAGILSNLTCNNYKNKMMVCQVGGIEALVRTVLRAGDREDITEPA 464
L++LL +D VV AA ++ L+ ++ I AL+R + D E T A
Sbjct: 13 LIKLLSDEDQVVVCQAAMMVHQLSKKEASRHAIMNSPQMIAALIRALATTDDMET-TRCA 189
Query: 465 ICALRHLTSRHQEAEMAQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANH 524
L +L S H++ +A + G+P +VKLL P L A L L +
Sbjct: 190 AGTLHNL-SHHRQGLLA---IFKSGGIPALVKLLSSPVESVLFYAITTLHNLLLHQEGSK 357
Query: 525 APLREQGAIPRLVQLLVR 542
+R G + ++V LL R
Sbjct: 358 MAVRMAGGLQKMVALLQR 411
>12505
Length = 836
Score = 115 bits (289), Expect(2) = 6e-30, Method: Compositional matrix adjust.
Identities = 57/80 (71%), Positives = 60/80 (75%)
Frame = -3
Query: 592 GLNTIPLFVQLLYSPIENIQRVAAGVLCELAQDKXXXXXXXXXXXXXPLTELLHSRNEGV 651
G+ + + QLLYSPIENIQRVAAGVLCELA DK PLTELLHSRNEGV
Sbjct: 732 GVGAVLRYHQLLYSPIENIQRVAAGVLCELAADKEGAEMIEQEGATAPLTELLHSRNEGV 553
Query: 652 ATYAAAVLFRMSEDKPQDYK 671
TYAAAVLFRMSEDKPQDYK
Sbjct: 552 XTYAAAVLFRMSEDKPQDYK 493
Score = 33.9 bits (76), Expect(2) = 6e-30, Method: Compositional matrix adjust.
Identities = 17/31 (54%), Positives = 23/31 (74%), Gaps = 3/31 (9%)
Frame = -2
Query: 671 KKRLSVELTSSLFRTEPMAWNETA---DLGL 698
+KRLS+ELTSSL+R + M W+E D+GL
Sbjct: 496 QKRLSMELTSSLYRGDNMNWSEPPGFEDVGL 404
Score = 80.9 bits (198), Expect = 2e-15, Method: Composition-based stats.
Identities = 37/44 (84%), Positives = 43/44 (97%)
Frame = -1
Query: 215 AGTLHNLSHHREGLLAIFKSGGIPALVKMLGSPVDSVLFYAITT 258
AGTLHNLSHHR+GLLAIF+SGGIPALVK+L SP++SVLFYAIT+
Sbjct: 833 AGTLHNLSHHRQGLLAIFRSGGIPALVKLLSSPMESVLFYAITS 702
>38361
Length = 227
Score = 107 bits (268), Expect(2) = 9e-28, Method: Compositional matrix adjust.
Identities = 50/63 (79%), Positives = 55/63 (87%)
Frame = -1
Query: 457 REDITEPAICALRHLTSRHQEAEMAQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRN 516
R + ++CALRHLTSRH EAEMAQNAVRLHYGLPV+VKLLHPPS WPLIKA VGL+RN
Sbjct: 191 RTSLNLDSVCALRHLTSRHPEAEMAQNAVRLHYGLPVLVKLLHPPSRWPLIKAVVGLVRN 12
Query: 517 LAL 519
LAL
Sbjct: 11 LAL 3
Score = 34.7 bits (78), Expect(2) = 9e-28, Method: Compositional matrix adjust.
Identities = 14/17 (82%), Positives = 16/17 (94%)
Frame = -3
Query: 447 LVRTVLRAGDREDITEP 463
VRTV++AGDREDITEP
Sbjct: 225 FVRTVMQAGDREDITEP 175
>17600
Length = 752
Score = 107 bits (267), Expect = 2e-23, Method: Compositional matrix adjust.
Identities = 67/135 (49%), Positives = 83/135 (61%), Gaps = 15/135 (11%)
Frame = +1
Query: 639 PLTELLHSRNEGVATYAAAVLFRMSEDKPQDYKKRLSVELTSSLFRTEPMAWNETA---D 695
PLT+LLHSRNEGVATYAAAVLFRMSEDKPQDYKKRLS+ELTSSL+R + M W+E D
Sbjct: 292 PLTDLLHSRNEGVATYAAAVLFRMSEDKPQDYKKRLSMELTSSLYRGDNMNWSEPPGFED 471
Query: 696 LGLDIGAQGEPLGYRQDDPSYRSFHSGGY--------GQDALGMDPMMEHEMGGHHPGA- 746
+GL +P+ +Q P ++ S Y G+ G D + + M G GA
Sbjct: 472 MGLLTDTSRDPMYSQQQLPPHQGSQSSMYSGSQHDMQGRPPTGYDQVPVNSMQGLDLGAA 651
Query: 747 ---DYPVDGLPDLGH 758
P+D +PDLG
Sbjct: 652 GAYGGPLDNIPDLGQ 696
>12579
Length = 1870
Score = 96.3 bits (238), Expect = 5e-20, Method: Compositional matrix adjust.
Identities = 61/123 (49%), Positives = 78/123 (63%), Gaps = 6/123 (4%)
Frame = +2
Query: 10 LDMAMEPDRKAAVSHWQQQSYL-DSGIHSGATTTAPSLSGKGNPEE---EDVDTSQVLYE 65
LDM ++ + WQQ YL DSGIHSGATT APS+S KG+ EE D+D ++ +++
Sbjct: 92 LDMPVD-SKHEQTMMWQQNQYLADSGIHSGATTQAPSISSKGHGEELEEGDMDPTK-MFD 265
Query: 66 WEQGFSQSFTQ--EQVADIDGQYAMTRAQRVRAAMFPETLDEGMQIPSTQFDAAHPTNVQ 123
W G FT EQV +++ Q TR QRVRAA+FPE+L EG+QIPSTQ PT V
Sbjct: 266 W--GLPDPFTPQPEQVEEMNQQLNQTRPQRVRAAIFPESLPEGVQIPSTQVHPDQPTAVX 439
Query: 124 RLA 126
LA
Sbjct: 440 *LA 448
>36452
Length = 607
Score = 45.8 bits (107), Expect = 7e-05, Method: Compositional matrix adjust.
Identities = 44/190 (23%), Positives = 85/190 (44%), Gaps = 5/190 (2%)
Frame = +1
Query: 207 DVETARCTAGTLHNLSHHREGLLAIFKSGGIPALVKMLGSPVDSVLFYAITTLHNLLLHQ 266
DVE ARC A L + S ++ A+ ++G IP L K+L SP + +L + TL +
Sbjct: 7 DVEVARCGALALWSCSKSKKNKEAMQRAGAIPLLAKLLKSPHEDMLIPVVGTLQE-CASE 183
Query: 267 EGAKMAVRLAGGLQKMVALLNKTNVKFLA---ITTDCLQIL--AYGNQESKLIILASGGP 321
++A+R G ++ +V L + A + C + +E++ ++ GG
Sbjct: 184 PSYRLAIRTEGMIEDLVKNLKSSVPDKPANPELQMHCASAIFKCAEEKETRDLVRQYGGL 363
Query: 322 QALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLHLTDPSQRLVQNC 381
LV ++ ++LL + + ++ N E ++ L LT+ + ++ N
Sbjct: 364 DPLVGLLNKMDNKELLAAATGAIWKCAISPENVARFQELKCIELLVALLTNQPEEVLVNV 543
Query: 382 LWTLRNLSDA 391
+ L L+ A
Sbjct: 544 VGALGELAKA 573
Score = 32.0 bits (71), Expect = 0.89, Method: Compositional matrix adjust.
Identities = 56/215 (26%), Positives = 88/215 (40%), Gaps = 5/215 (2%)
Frame = +1
Query: 382 LWTLRNLSDAATKQEGME--GLLGTLVQLLGSDDINVVTCAAGILSNLTCNNYKNKMMVC 439
LW+ S + +E M+ G + L +LL S +++ G L + ++ +
Sbjct: 40 LWSC---SKSKKNKEAMQRAGAIPLLAKLLKSPHEDMLIPVVGTLQECA-SEPSYRLAIR 207
Query: 440 QVGGIEALVRTVLRAGDREDITEPAI---CALRHLTSRHQEAEMAQNAVRLHYGLPVVVK 496
G IE LV+ L++ + P + CA + E + ++ VR + GL +V
Sbjct: 208 TEGMIEDLVKN-LKSSVPDKPANPELQMHCA--SAIFKCAEEKETRDLVRQYGGLDPLVG 378
Query: 497 LLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLLVRAHQDTQRRTSMGGT 556
LL+ + L+ A G I A+ P N A +E I LV LL T
Sbjct: 379 LLNKMDNKELLAAATGAIWKCAISPENVARFQELKCIELLVALL---------------T 513
Query: 557 QQQFVEGVRMEEIVEGCTGALHILARDVHNRIVIR 591
Q EE++ GAL LA+ NR IR
Sbjct: 514 NQP-------EEVLVNVVGALGELAKAQPNRAQIR 597
>28685
Length = 834
Score = 35.0 bits (79), Expect = 0.11, Method: Composition-based stats.
Identities = 19/36 (52%), Positives = 20/36 (55%), Gaps = 7/36 (19%)
Frame = +2
Query: 753 LPDLGHAQDL----MD---GLPPGDSNQLAWFDTDL 781
LPDLG DL +D G PPGD WFDTDL
Sbjct: 23 LPDLGPGSDLNFDSIDPNLGAPPGDGGPSIWFDTDL 130
>36960
Length = 551
Score = 29.3 bits (64), Expect = 6.3, Method: Composition-based stats.
Identities = 16/43 (37%), Positives = 23/43 (53%)
Frame = +3
Query: 231 IFKSGGIPALVKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAV 273
I +GGIP ++ L S + + AITTL L+ Q A + V
Sbjct: 321 IVTNGGIPLVINCLSSCSEETVMSAITTLMYLITPQSQAAITV 449
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000379488 | hsapiens_gene_ensembl | Catenin beta-1
(Beta-catenin). [Source:Uniprot/SWISSPROT;Acc:P35222]
(781 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
14657 507 e-144
15086 295 5e-80
12505 115 6e-30
38361 107 9e-28
17600 107 2e-23
12579 96 5e-20
36452 46 7e-05
28685 35 0.11
36960 29 6.3
>14657
Length = 918
Score = 507 bits (1305), Expect = e-144, Method: Compositional matrix adjust.
Identities = 251/305 (82%), Positives = 272/305 (89%), Gaps = 1/305 (0%)
Frame = -3
Query: 102 TLDEGMQIPSTQFDAAHPTNVQRLAEPSQMLKHAVVNLINYQDDAELATRAIPELTKLLN 161
TL EG+QIPSTQ PT VQRL+EPSQMLKHAVVNLINYQDDA+LATRAIPEL KLL
Sbjct: 916 TLPEGVQIPSTQVHPDEPTAVQRLSEPSQMLKHAVVNLINYQDDADLATRAIPELIKLLX 737
Query: 162 DEDQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAIVRTMQNTNDVETARCTAGTLHNL 221
DED VVV +AA+MVHQLSKKEASRHAIM SPQM++A++R M NT D+ET RC AGTLHNL
Sbjct: 736 DEDXVVVYQAAMMVHQLSKKEASRHAIMNSPQMIAALIRAMANTEDIETTRCAAGTLHNL 557
Query: 222 SHHREGLLAIFKSGGIPALVKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQK 281
SHHR+GLLAIFKSGGIPALVK+L SP++SVLFYAITTLHNLLLHQEG+KMAVRLAGGLQK
Sbjct: 556 SHHRQGLLAIFKSGGIPALVKLLSSPMESVLFYAITTLHNLLLHQEGSKMAVRLAGGLQK 377
Query: 282 MVALLNK-TNVKFLAITTDCLQILAYGNQESKLIILASGGPQALVNIMRTYTYEKLLWTT 340
MVALL + NVKFLAITTDCLQILAYGNQESKLIILASGGP LV IM++YTYEKLLWTT
Sbjct: 376 MVALLQRNNNVKFLAITTDCLQILAYGNQESKLIILASGGPGELVRIMKSYTYEKLLWTT 197
Query: 341 SRVLKVLSVCSSNKPAIVEAGGMQALGLHLTDPSQRLVQNCLWTLRNLSDAATKQEGMEG 400
SRVLKVLSVC SNKPAIVEAGGMQAL +HL SQRLVQNCLW+LRNLSDAATK + MEG
Sbjct: 196 SRVLKVLSVCPSNKPAIVEAGGMQALAMHLGHQSQRLVQNCLWSLRNLSDAATKMDNMEG 17
Query: 401 LLGTL 405
LL L
Sbjct: 16 LLHML 2
Score = 33.9 bits (76), Expect = 0.27, Method: Compositional matrix adjust.
Identities = 49/177 (27%), Positives = 78/177 (44%), Gaps = 4/177 (2%)
Frame = -3
Query: 370 LTDPSQRLVQNC--LWTLRNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCAAGILSNL 427
L++PSQ L L ++ +D AT+ + L++LL +D VV AA ++ L
Sbjct: 847 LSEPSQMLKHAVVNLINYQDDADLATRA------IPELIKLLXDEDXVVVYQAAMMVHQL 686
Query: 428 TCNNYKNKMMVCQVGGIEALVRTVLRAGDREDITEPAICA--LRHLTSRHQEAEMAQNAV 485
+ ++ I AL+R + + EDI E CA H S H++ +A +
Sbjct: 685 SKKEASRHAIMNSPQMIAALIRAM---ANTEDI-ETTRCAAGTLHNLSHHRQGLLA---I 527
Query: 486 RLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLLVR 542
G+P +VKLL P L A L L + +R G + ++V LL R
Sbjct: 526 FKSGGIPALVKLLSSPMESVLFYAITTLHNLLLHQEGSKMAVRLAGGLQKMVALLQR 356
>15086
Length = 548
Score = 295 bits (755), Expect = 5e-80, Method: Compositional matrix adjust.
Identities = 143/171 (83%), Positives = 159/171 (92%), Gaps = 1/171 (0%)
Frame = +1
Query: 152 AIPELTKLLNDEDQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAIVRTMQNTNDVETA 211
AIPEL KLL+DEDQVVV +AA+MVHQLSKKEASRHAIM SPQM++A++R + T+D+ET
Sbjct: 1 AIPELIKLLSDEDQVVVCQAAMMVHQLSKKEASRHAIMNSPQMIAALIRALATTDDMETT 180
Query: 212 RCTAGTLHNLSHHREGLLAIFKSGGIPALVKMLGSPVDSVLFYAITTLHNLLLHQEGAKM 271
RC AGTLHNLSHHR+GLLAIFKSGGIPALVK+L SPV+SVLFYAITTLHNLLLHQEG+KM
Sbjct: 181 RCAAGTLHNLSHHRQGLLAIFKSGGIPALVKLLSSPVESVLFYAITTLHNLLLHQEGSKM 360
Query: 272 AVRLAGGLQKMVALLNK-TNVKFLAITTDCLQILAYGNQESKLIILASGGP 321
AVR+AGGLQKMVALL + NVKFLAITTDCLQILAYGNQESKLIILASGGP
Sbjct: 361 AVRMAGGLQKMVALLQRNNNVKFLAITTDCLQILAYGNQESKLIILASGGP 513
Score = 31.6 bits (70), Expect = 1.4, Method: Compositional matrix adjust.
Identities = 39/138 (28%), Positives = 61/138 (44%)
Frame = +1
Query: 405 LVQLLGSDDINVVTCAAGILSNLTCNNYKNKMMVCQVGGIEALVRTVLRAGDREDITEPA 464
L++LL +D VV AA ++ L+ ++ I AL+R + D E T A
Sbjct: 13 LIKLLSDEDQVVVCQAAMMVHQLSKKEASRHAIMNSPQMIAALIRALATTDDMET-TRCA 189
Query: 465 ICALRHLTSRHQEAEMAQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANH 524
L +L S H++ +A + G+P +VKLL P L A L L +
Sbjct: 190 AGTLHNL-SHHRQGLLA---IFKSGGIPALVKLLSSPVESVLFYAITTLHNLLLHQEGSK 357
Query: 525 APLREQGAIPRLVQLLVR 542
+R G + ++V LL R
Sbjct: 358 MAVRMAGGLQKMVALLQR 411
>12505
Length = 836
Score = 115 bits (289), Expect(2) = 6e-30, Method: Compositional matrix adjust.
Identities = 57/80 (71%), Positives = 60/80 (75%)
Frame = -3
Query: 592 GLNTIPLFVQLLYSPIENIQRVAAGVLCELAQDKXXXXXXXXXXXXXPLTELLHSRNEGV 651
G+ + + QLLYSPIENIQRVAAGVLCELA DK PLTELLHSRNEGV
Sbjct: 732 GVGAVLRYHQLLYSPIENIQRVAAGVLCELAADKEGAEMIEQEGATAPLTELLHSRNEGV 553
Query: 652 ATYAAAVLFRMSEDKPQDYK 671
TYAAAVLFRMSEDKPQDYK
Sbjct: 552 XTYAAAVLFRMSEDKPQDYK 493
Score = 33.9 bits (76), Expect(2) = 6e-30, Method: Compositional matrix adjust.
Identities = 17/31 (54%), Positives = 23/31 (74%), Gaps = 3/31 (9%)
Frame = -2
Query: 671 KKRLSVELTSSLFRTEPMAWNETA---DLGL 698
+KRLS+ELTSSL+R + M W+E D+GL
Sbjct: 496 QKRLSMELTSSLYRGDNMNWSEPPGFEDVGL 404
Score = 80.9 bits (198), Expect = 2e-15, Method: Composition-based stats.
Identities = 37/44 (84%), Positives = 43/44 (97%)
Frame = -1
Query: 215 AGTLHNLSHHREGLLAIFKSGGIPALVKMLGSPVDSVLFYAITT 258
AGTLHNLSHHR+GLLAIF+SGGIPALVK+L SP++SVLFYAIT+
Sbjct: 833 AGTLHNLSHHRQGLLAIFRSGGIPALVKLLSSPMESVLFYAITS 702
>38361
Length = 227
Score = 107 bits (268), Expect(2) = 9e-28, Method: Compositional matrix adjust.
Identities = 50/63 (79%), Positives = 55/63 (87%)
Frame = -1
Query: 457 REDITEPAICALRHLTSRHQEAEMAQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRN 516
R + ++CALRHLTSRH EAEMAQNAVRLHYGLPV+VKLLHPPS WPLIKA VGL+RN
Sbjct: 191 RTSLNLDSVCALRHLTSRHPEAEMAQNAVRLHYGLPVLVKLLHPPSRWPLIKAVVGLVRN 12
Query: 517 LAL 519
LAL
Sbjct: 11 LAL 3
Score = 34.7 bits (78), Expect(2) = 9e-28, Method: Compositional matrix adjust.
Identities = 14/17 (82%), Positives = 16/17 (94%)
Frame = -3
Query: 447 LVRTVLRAGDREDITEP 463
VRTV++AGDREDITEP
Sbjct: 225 FVRTVMQAGDREDITEP 175
>17600
Length = 752
Score = 107 bits (267), Expect = 2e-23, Method: Compositional matrix adjust.
Identities = 67/135 (49%), Positives = 83/135 (61%), Gaps = 15/135 (11%)
Frame = +1
Query: 639 PLTELLHSRNEGVATYAAAVLFRMSEDKPQDYKKRLSVELTSSLFRTEPMAWNETA---D 695
PLT+LLHSRNEGVATYAAAVLFRMSEDKPQDYKKRLS+ELTSSL+R + M W+E D
Sbjct: 292 PLTDLLHSRNEGVATYAAAVLFRMSEDKPQDYKKRLSMELTSSLYRGDNMNWSEPPGFED 471
Query: 696 LGLDIGAQGEPLGYRQDDPSYRSFHSGGY--------GQDALGMDPMMEHEMGGHHPGA- 746
+GL +P+ +Q P ++ S Y G+ G D + + M G GA
Sbjct: 472 MGLLTDTSRDPMYSQQQLPPHQGSQSSMYSGSQHDMQGRPPTGYDQVPVNSMQGLDLGAA 651
Query: 747 ---DYPVDGLPDLGH 758
P+D +PDLG
Sbjct: 652 GAYGGPLDNIPDLGQ 696
>12579
Length = 1870
Score = 96.3 bits (238), Expect = 5e-20, Method: Compositional matrix adjust.
Identities = 61/123 (49%), Positives = 78/123 (63%), Gaps = 6/123 (4%)
Frame = +2
Query: 10 LDMAMEPDRKAAVSHWQQQSYL-DSGIHSGATTTAPSLSGKGNPEE---EDVDTSQVLYE 65
LDM ++ + WQQ YL DSGIHSGATT APS+S KG+ EE D+D ++ +++
Sbjct: 92 LDMPVD-SKHEQTMMWQQNQYLADSGIHSGATTQAPSISSKGHGEELEEGDMDPTK-MFD 265
Query: 66 WEQGFSQSFTQ--EQVADIDGQYAMTRAQRVRAAMFPETLDEGMQIPSTQFDAAHPTNVQ 123
W G FT EQV +++ Q TR QRVRAA+FPE+L EG+QIPSTQ PT V
Sbjct: 266 W--GLPDPFTPQPEQVEEMNQQLNQTRPQRVRAAIFPESLPEGVQIPSTQVHPDQPTAVX 439
Query: 124 RLA 126
LA
Sbjct: 440 *LA 448
>36452
Length = 607
Score = 45.8 bits (107), Expect = 7e-05, Method: Compositional matrix adjust.
Identities = 44/190 (23%), Positives = 85/190 (44%), Gaps = 5/190 (2%)
Frame = +1
Query: 207 DVETARCTAGTLHNLSHHREGLLAIFKSGGIPALVKMLGSPVDSVLFYAITTLHNLLLHQ 266
DVE ARC A L + S ++ A+ ++G IP L K+L SP + +L + TL +
Sbjct: 7 DVEVARCGALALWSCSKSKKNKEAMQRAGAIPLLAKLLKSPHEDMLIPVVGTLQE-CASE 183
Query: 267 EGAKMAVRLAGGLQKMVALLNKTNVKFLA---ITTDCLQIL--AYGNQESKLIILASGGP 321
++A+R G ++ +V L + A + C + +E++ ++ GG
Sbjct: 184 PSYRLAIRTEGMIEDLVKNLKSSVPDKPANPELQMHCASAIFKCAEEKETRDLVRQYGGL 363
Query: 322 QALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLHLTDPSQRLVQNC 381
LV ++ ++LL + + ++ N E ++ L LT+ + ++ N
Sbjct: 364 DPLVGLLNKMDNKELLAAATGAIWKCAISPENVARFQELKCIELLVALLTNQPEEVLVNV 543
Query: 382 LWTLRNLSDA 391
+ L L+ A
Sbjct: 544 VGALGELAKA 573
Score = 32.0 bits (71), Expect = 0.89, Method: Compositional matrix adjust.
Identities = 56/215 (26%), Positives = 88/215 (40%), Gaps = 5/215 (2%)
Frame = +1
Query: 382 LWTLRNLSDAATKQEGME--GLLGTLVQLLGSDDINVVTCAAGILSNLTCNNYKNKMMVC 439
LW+ S + +E M+ G + L +LL S +++ G L + ++ +
Sbjct: 40 LWSC---SKSKKNKEAMQRAGAIPLLAKLLKSPHEDMLIPVVGTLQECA-SEPSYRLAIR 207
Query: 440 QVGGIEALVRTVLRAGDREDITEPAI---CALRHLTSRHQEAEMAQNAVRLHYGLPVVVK 496
G IE LV+ L++ + P + CA + E + ++ VR + GL +V
Sbjct: 208 TEGMIEDLVKN-LKSSVPDKPANPELQMHCA--SAIFKCAEEKETRDLVRQYGGLDPLVG 378
Query: 497 LLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLLVRAHQDTQRRTSMGGT 556
LL+ + L+ A G I A+ P N A +E I LV LL T
Sbjct: 379 LLNKMDNKELLAAATGAIWKCAISPENVARFQELKCIELLVALL---------------T 513
Query: 557 QQQFVEGVRMEEIVEGCTGALHILARDVHNRIVIR 591
Q EE++ GAL LA+ NR IR
Sbjct: 514 NQP-------EEVLVNVVGALGELAKAQPNRAQIR 597
>28685
Length = 834
Score = 35.0 bits (79), Expect = 0.11, Method: Composition-based stats.
Identities = 19/36 (52%), Positives = 20/36 (55%), Gaps = 7/36 (19%)
Frame = +2
Query: 753 LPDLGHAQDL----MD---GLPPGDSNQLAWFDTDL 781
LPDLG DL +D G PPGD WFDTDL
Sbjct: 23 LPDLGPGSDLNFDSIDPNLGAPPGDGGPSIWFDTDL 130
>36960
Length = 551
Score = 29.3 bits (64), Expect = 6.3, Method: Composition-based stats.
Identities = 16/43 (37%), Positives = 23/43 (53%)
Frame = +3
Query: 231 IFKSGGIPALVKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAV 273
I +GGIP ++ L S + + AITTL L+ Q A + V
Sbjct: 321 IVTNGGIPLVINCLSSCSEETVMSAITTLMYLITPQSQAAITV 449
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000379493 | hsapiens_gene_ensembl | Catenin beta-1
(Beta-catenin). [Source:Uniprot/SWISSPROT;Acc:P35222]
(781 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
14657 508 e-144
15086 295 5e-80
12505 115 6e-30
38361 107 1e-27
17600 107 2e-23
12579 96 5e-20
36452 46 7e-05
28685 35 0.12
36960 29 6.3
>14657
Length = 918
Score = 508 bits (1307), Expect = e-144, Method: Compositional matrix adjust.
Identities = 251/305 (82%), Positives = 272/305 (89%), Gaps = 1/305 (0%)
Frame = -3
Query: 102 TLDEGMQIPSTQFDAAHPTNVQRLAEPSQMLKHAVVNLINYQDDAELATRAIPELTKLLN 161
TL EG+QIPSTQ PT VQRL+EPSQMLKHAVVNLINYQDDA+LATRAIPEL KLL
Sbjct: 916 TLPEGVQIPSTQVHPDEPTAVQRLSEPSQMLKHAVVNLINYQDDADLATRAIPELIKLLX 737
Query: 162 DEDQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAIVRTMQNTNDVETARCTAGTLHNL 221
DED VVV +AA+MVHQLSKKEASRHAIM SPQM++A++R M NT D+ET RC AGTLHNL
Sbjct: 736 DEDXVVVYQAAMMVHQLSKKEASRHAIMNSPQMIAALIRAMANTEDIETTRCAAGTLHNL 557
Query: 222 SHHREGLLAIFKSGGIPALVKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQK 281
SHHR+GLLAIFKSGGIPALVK+L SP++SVLFYAITTLHNLLLHQEG+KMAVRLAGGLQK
Sbjct: 556 SHHRQGLLAIFKSGGIPALVKLLSSPMESVLFYAITTLHNLLLHQEGSKMAVRLAGGLQK 377
Query: 282 MVALLNK-TNVKFLAITTDCLQILAYGNQESKLIILASGGPQALVNIMRTYTYEKLLWTT 340
MVALL + NVKFLAITTDCLQILAYGNQESKLIILASGGP LV IM++YTYEKLLWTT
Sbjct: 376 MVALLQRNNNVKFLAITTDCLQILAYGNQESKLIILASGGPGELVRIMKSYTYEKLLWTT 197
Query: 341 SRVLKVLSVCSSNKPAIVEAGGMQALGLHLTDPSQRLVQNCLWTLRNLSDAATKQEGMEG 400
SRVLKVLSVC SNKPAIVEAGGMQAL +HL SQRLVQNCLW+LRNLSDAATK + MEG
Sbjct: 196 SRVLKVLSVCPSNKPAIVEAGGMQALAMHLGHQSQRLVQNCLWSLRNLSDAATKMDNMEG 17
Query: 401 LLGTL 405
LL L
Sbjct: 16 LLHML 2
Score = 33.9 bits (76), Expect = 0.24, Method: Compositional matrix adjust.
Identities = 49/177 (27%), Positives = 78/177 (44%), Gaps = 4/177 (2%)
Frame = -3
Query: 370 LTDPSQRLVQNC--LWTLRNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCAAGILSNL 427
L++PSQ L L ++ +D AT+ + L++LL +D VV AA ++ L
Sbjct: 847 LSEPSQMLKHAVVNLINYQDDADLATRA------IPELIKLLXDEDXVVVYQAAMMVHQL 686
Query: 428 TCNNYKNKMMVCQVGGIEALVRTVLRAGDREDITEPAICA--LRHLTSRHQEAEMAQNAV 485
+ ++ I AL+R + + EDI E CA H S H++ +A +
Sbjct: 685 SKKEASRHAIMNSPQMIAALIRAM---ANTEDI-ETTRCAAGTLHNLSHHRQGLLA---I 527
Query: 486 RLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLLVR 542
G+P +VKLL P L A L L + +R G + ++V LL R
Sbjct: 526 FKSGGIPALVKLLSSPMESVLFYAITTLHNLLLHQEGSKMAVRLAGGLQKMVALLQR 356
>15086
Length = 548
Score = 295 bits (755), Expect = 5e-80, Method: Compositional matrix adjust.
Identities = 143/171 (83%), Positives = 159/171 (92%), Gaps = 1/171 (0%)
Frame = +1
Query: 152 AIPELTKLLNDEDQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAIVRTMQNTNDVETA 211
AIPEL KLL+DEDQVVV +AA+MVHQLSKKEASRHAIM SPQM++A++R + T+D+ET
Sbjct: 1 AIPELIKLLSDEDQVVVCQAAMMVHQLSKKEASRHAIMNSPQMIAALIRALATTDDMETT 180
Query: 212 RCTAGTLHNLSHHREGLLAIFKSGGIPALVKMLGSPVDSVLFYAITTLHNLLLHQEGAKM 271
RC AGTLHNLSHHR+GLLAIFKSGGIPALVK+L SPV+SVLFYAITTLHNLLLHQEG+KM
Sbjct: 181 RCAAGTLHNLSHHRQGLLAIFKSGGIPALVKLLSSPVESVLFYAITTLHNLLLHQEGSKM 360
Query: 272 AVRLAGGLQKMVALLNK-TNVKFLAITTDCLQILAYGNQESKLIILASGGP 321
AVR+AGGLQKMVALL + NVKFLAITTDCLQILAYGNQESKLIILASGGP
Sbjct: 361 AVRMAGGLQKMVALLQRNNNVKFLAITTDCLQILAYGNQESKLIILASGGP 513
Score = 31.6 bits (70), Expect = 1.4, Method: Compositional matrix adjust.
Identities = 39/138 (28%), Positives = 61/138 (44%)
Frame = +1
Query: 405 LVQLLGSDDINVVTCAAGILSNLTCNNYKNKMMVCQVGGIEALVRTVLRAGDREDITEPA 464
L++LL +D VV AA ++ L+ ++ I AL+R + D E T A
Sbjct: 13 LIKLLSDEDQVVVCQAAMMVHQLSKKEASRHAIMNSPQMIAALIRALATTDDMET-TRCA 189
Query: 465 ICALRHLTSRHQEAEMAQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANH 524
L +L S H++ +A + G+P +VKLL P L A L L +
Sbjct: 190 AGTLHNL-SHHRQGLLA---IFKSGGIPALVKLLSSPVESVLFYAITTLHNLLLHQEGSK 357
Query: 525 APLREQGAIPRLVQLLVR 542
+R G + ++V LL R
Sbjct: 358 MAVRMAGGLQKMVALLQR 411
>12505
Length = 836
Score = 115 bits (289), Expect(2) = 6e-30, Method: Compositional matrix adjust.
Identities = 57/80 (71%), Positives = 60/80 (75%)
Frame = -3
Query: 592 GLNTIPLFVQLLYSPIENIQRVAAGVLCELAQDKXXXXXXXXXXXXXPLTELLHSRNEGV 651
G+ + + QLLYSPIENIQRVAAGVLCELA DK PLTELLHSRNEGV
Sbjct: 732 GVGAVLRYHQLLYSPIENIQRVAAGVLCELAADKEGAEMIEQEGATAPLTELLHSRNEGV 553
Query: 652 ATYAAAVLFRMSEDKPQDYK 671
TYAAAVLFRMSEDKPQDYK
Sbjct: 552 XTYAAAVLFRMSEDKPQDYK 493
Score = 33.9 bits (76), Expect(2) = 6e-30, Method: Compositional matrix adjust.
Identities = 17/31 (54%), Positives = 23/31 (74%), Gaps = 3/31 (9%)
Frame = -2
Query: 671 KKRLSVELTSSLFRTEPMAWNETA---DLGL 698
+KRLS+ELTSSL+R + M W+E D+GL
Sbjct: 496 QKRLSMELTSSLYRGDNMNWSEPPGFEDVGL 404
Score = 80.9 bits (198), Expect = 2e-15, Method: Composition-based stats.
Identities = 37/44 (84%), Positives = 43/44 (97%)
Frame = -1
Query: 215 AGTLHNLSHHREGLLAIFKSGGIPALVKMLGSPVDSVLFYAITT 258
AGTLHNLSHHR+GLLAIF+SGGIPALVK+L SP++SVLFYAIT+
Sbjct: 833 AGTLHNLSHHRQGLLAIFRSGGIPALVKLLSSPMESVLFYAITS 702
>38361
Length = 227
Score = 107 bits (268), Expect(2) = 1e-27, Method: Compositional matrix adjust.
Identities = 50/63 (79%), Positives = 55/63 (87%)
Frame = -1
Query: 457 REDITEPAICALRHLTSRHQEAEMAQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRN 516
R + ++CALRHLTSRH EAEMAQNAVRLHYGLPV+VKLLHPPS WPLIKA VGL+RN
Sbjct: 191 RTSLNLDSVCALRHLTSRHPEAEMAQNAVRLHYGLPVLVKLLHPPSRWPLIKAVVGLVRN 12
Query: 517 LAL 519
LAL
Sbjct: 11 LAL 3
Score = 34.7 bits (78), Expect(2) = 1e-27, Method: Compositional matrix adjust.
Identities = 14/17 (82%), Positives = 16/17 (94%)
Frame = -3
Query: 447 LVRTVLRAGDREDITEP 463
VRTV++AGDREDITEP
Sbjct: 225 FVRTVMQAGDREDITEP 175
>17600
Length = 752
Score = 107 bits (267), Expect = 2e-23, Method: Compositional matrix adjust.
Identities = 67/135 (49%), Positives = 83/135 (61%), Gaps = 15/135 (11%)
Frame = +1
Query: 639 PLTELLHSRNEGVATYAAAVLFRMSEDKPQDYKKRLSVELTSSLFRTEPMAWNETA---D 695
PLT+LLHSRNEGVATYAAAVLFRMSEDKPQDYKKRLS+ELTSSL+R + M W+E D
Sbjct: 292 PLTDLLHSRNEGVATYAAAVLFRMSEDKPQDYKKRLSMELTSSLYRGDNMNWSEPPGFED 471
Query: 696 LGLDIGAQGEPLGYRQDDPSYRSFHSGGY--------GQDALGMDPMMEHEMGGHHPGA- 746
+GL +P+ +Q P ++ S Y G+ G D + + M G GA
Sbjct: 472 MGLLTDTSRDPMYSQQQLPPHQGSQSSMYSGSQHDMQGRPPTGYDQVPVNSMQGLDLGAA 651
Query: 747 ---DYPVDGLPDLGH 758
P+D +PDLG
Sbjct: 652 GAYGGPLDNIPDLGQ 696
>12579
Length = 1870
Score = 96.3 bits (238), Expect = 5e-20, Method: Compositional matrix adjust.
Identities = 61/123 (49%), Positives = 78/123 (63%), Gaps = 6/123 (4%)
Frame = +2
Query: 10 LDMAMEPDRKAAVSHWQQQSYL-DSGIHSGATTTAPSLSGKGNPEE---EDVDTSQVLYE 65
LDM ++ + WQQ YL DSGIHSGATT APS+S KG+ EE D+D ++ +++
Sbjct: 92 LDMPVD-SKHEQTMMWQQNQYLADSGIHSGATTQAPSISSKGHGEELEEGDMDPTK-MFD 265
Query: 66 WEQGFSQSFTQ--EQVADIDGQYAMTRAQRVRAAMFPETLDEGMQIPSTQFDAAHPTNVQ 123
W G FT EQV +++ Q TR QRVRAA+FPE+L EG+QIPSTQ PT V
Sbjct: 266 W--GLPDPFTPQPEQVEEMNQQLNQTRPQRVRAAIFPESLPEGVQIPSTQVHPDQPTAVX 439
Query: 124 RLA 126
LA
Sbjct: 440 *LA 448
>36452
Length = 607
Score = 45.8 bits (107), Expect = 7e-05, Method: Compositional matrix adjust.
Identities = 44/190 (23%), Positives = 85/190 (44%), Gaps = 5/190 (2%)
Frame = +1
Query: 207 DVETARCTAGTLHNLSHHREGLLAIFKSGGIPALVKMLGSPVDSVLFYAITTLHNLLLHQ 266
DVE ARC A L + S ++ A+ ++G IP L K+L SP + +L + TL +
Sbjct: 7 DVEVARCGALALWSCSKSKKNKEAMQRAGAIPLLAKLLKSPHEDMLIPVVGTLQE-CASE 183
Query: 267 EGAKMAVRLAGGLQKMVALLNKTNVKFLA---ITTDCLQIL--AYGNQESKLIILASGGP 321
++A+R G ++ +V L + A + C + +E++ ++ GG
Sbjct: 184 PSYRLAIRTEGMIEDLVKNLKSSVPDKPANPELQMHCASAIFKCAEEKETRDLVRQYGGL 363
Query: 322 QALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLHLTDPSQRLVQNC 381
LV ++ ++LL + + ++ N E ++ L LT+ + ++ N
Sbjct: 364 DPLVGLLNKMDNKELLAAATGAIWKCAISPENVARFQELKCIELLVALLTNQPEEVLVNV 543
Query: 382 LWTLRNLSDA 391
+ L L+ A
Sbjct: 544 VGALGELAKA 573
Score = 32.0 bits (71), Expect = 0.88, Method: Compositional matrix adjust.
Identities = 56/215 (26%), Positives = 88/215 (40%), Gaps = 5/215 (2%)
Frame = +1
Query: 382 LWTLRNLSDAATKQEGME--GLLGTLVQLLGSDDINVVTCAAGILSNLTCNNYKNKMMVC 439
LW+ S + +E M+ G + L +LL S +++ G L + ++ +
Sbjct: 40 LWSC---SKSKKNKEAMQRAGAIPLLAKLLKSPHEDMLIPVVGTLQECA-SEPSYRLAIR 207
Query: 440 QVGGIEALVRTVLRAGDREDITEPAI---CALRHLTSRHQEAEMAQNAVRLHYGLPVVVK 496
G IE LV+ L++ + P + CA + E + ++ VR + GL +V
Sbjct: 208 TEGMIEDLVKN-LKSSVPDKPANPELQMHCA--SAIFKCAEEKETRDLVRQYGGLDPLVG 378
Query: 497 LLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLLVRAHQDTQRRTSMGGT 556
LL+ + L+ A G I A+ P N A +E I LV LL T
Sbjct: 379 LLNKMDNKELLAAATGAIWKCAISPENVARFQELKCIELLVALL---------------T 513
Query: 557 QQQFVEGVRMEEIVEGCTGALHILARDVHNRIVIR 591
Q EE++ GAL LA+ NR IR
Sbjct: 514 NQP-------EEVLVNVVGALGELAKAQPNRAQIR 597
>28685
Length = 834
Score = 35.0 bits (79), Expect = 0.12, Method: Composition-based stats.
Identities = 19/36 (52%), Positives = 20/36 (55%), Gaps = 7/36 (19%)
Frame = +2
Query: 753 LPDLGHAQDL----MD---GLPPGDSNQLAWFDTDL 781
LPDLG DL +D G PPGD WFDTDL
Sbjct: 23 LPDLGPGSDLNFDSIDPNLGAPPGDGGPSIWFDTDL 130
>36960
Length = 551
Score = 29.3 bits (64), Expect = 6.3, Method: Composition-based stats.
Identities = 16/43 (37%), Positives = 23/43 (53%)
Frame = +3
Query: 231 IFKSGGIPALVKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAV 273
I +GGIP ++ L S + + AITTL L+ Q A + V
Sbjct: 321 IVTNGGIPLVINCLSSCSEETVMSAITTLMYLITPQSQAAITV 449
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000341289 | hsapiens_gene_ensembl | Tubulin
beta-2C chain (Tubulin beta-2 chain).
[Source:Uniprot/SWISSPROT;Acc:P68371]
(445 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
16482 473 e-134
13181 464 e-131
04882 441 e-124
00276 274 7e-74
28905 260 2e-70
31457 250 1e-66
25015 246 1e-65
39157 233 4e-65
12457 209 2e-54
05902 155 4e-38
06360 137 1e-32
03702 120 9e-28
17215 81 8e-16
19746 40 0.002
29025 36 0.040
>16482
Length = 837
Score = 473 bits (1216), Expect = e-134, Method: Compositional matrix adjust.
Identities = 226/246 (91%), Positives = 227/246 (92%)
Frame = +1
Query: 1 MREIVHLQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGKYV 60
MREIVH+QAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGKYV
Sbjct: 100 MREIVHMQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGKYV 279
Query: 61 PRAVLVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVV 120
PRAVLVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVV
Sbjct: 280 PRAVLVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVV 459
Query: 121 RKEAESCDCLQGFQXXXXXXXXXXXXXXXXXXXKIREEYPDRIMNTFSVVPSPKVSDTVV 180
RKEAESCDCLQGFQ KIREEYPDRIMNTFSVVPSPKVSDTVV
Sbjct: 460 RKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVV 639
Query: 181 EPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCL 240
EPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCL
Sbjct: 640 EPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCL 819
Query: 241 RFPGQL 246
RFPGQL
Sbjct: 820 RFPGQL 837
>13181
Length = 1092
Score = 464 bits (1195), Expect = e-131, Method: Compositional matrix adjust.
Identities = 218/220 (99%), Positives = 220/220 (100%)
Frame = -3
Query: 208 YDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFM 267
YDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFM
Sbjct: 1090 YDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFM 911
Query: 268 PGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVD 327
PGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAA+FRGRMSMKEVD
Sbjct: 910 PGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAMFRGRMSMKEVD 731
Query: 328 EQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTA 387
EQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATF+GNSTAIQELFKRISEQFTA
Sbjct: 730 EQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFVGNSTAIQELFKRISEQFTA 551
Query: 388 MFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQD 427
MFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQD
Sbjct: 550 MFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQD 431
>04882
Length = 1136
Score = 441 bits (1134), Expect = e-124, Method: Compositional matrix adjust.
Identities = 207/209 (99%), Positives = 209/209 (100%)
Frame = +2
Query: 219 TPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGS 278
TPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGS
Sbjct: 320 TPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGS 499
Query: 279 QQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNS 338
QQYRALTVPELTQQMFD+KNMMAACDPRHGRYLTVAA+FRGRMSMKEVDEQMLNVQNKNS
Sbjct: 500 QQYRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNS 679
Query: 339 SYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWY 398
SYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWY
Sbjct: 680 SYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWY 859
Query: 399 TGEGMDEMEFTEAESNMNDLVSEYQQYQD 427
TGEGMDEMEFTEAESNMNDLVSEYQQYQD
Sbjct: 860 TGEGMDEMEFTEAESNMNDLVSEYQQYQD 946
>00276
Length = 1330
Score = 274 bits (700), Expect = 7e-74, Method: Compositional matrix adjust.
Identities = 131/355 (36%), Positives = 203/355 (57%), Gaps = 8/355 (2%)
Frame = -3
Query: 78 SGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQXXX 137
+G + Q+ P+ V G+ A NN+A+GHYT G ELVD VLD +RK A+ C LQGF
Sbjct: 1328 TGTYRQL-SPEQLVTGKEDAANNYARGHYTIGKELVDLVLDRIRKLADQCTGLQGFLIFH 1152
Query: 138 XXXXXXXXXXXXXXXXKIREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVENTD 197
++ +Y + F + P+P+VS VVEPYN+ L+ H +E++D
Sbjct: 1151 SFGGGTGSGFTSLXMERLSVDYGKKSKLEFXIYPAPQVSTAVVEPYNSILTTHTTLEHSD 972
Query: 198 ETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNM 257
+ +DNEA+YDIC R L + PTY +LN L+ +S +T LRF G LN DL + N+
Sbjct: 971 CAFMVDNEAIYDICRRNLDIERPTYTNLNRLIXQIVSSITASLRFDGALNVDLTEFQTNL 792
Query: 258 VPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAVF 317
VP+PR+HF + +AP+ S + L V E+T F+ N + CDPRHG+Y+ ++
Sbjct: 791 VPYPRIHFPLATYAPVISAEKAYHEQLXVAEITNACFEPANQLVKCDPRHGKYMACCMLY 612
Query: 318 RGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPR--------GLKMSATFIG 369
RG + K+V+ + ++ K + FV+W P K + PP ++ + +
Sbjct: 611 RGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLS 432
Query: 370 NSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQ 424
N+TAI E + R+ +F M+ ++AF+HWY GEGM+E EF+EA ++ L +Y++
Sbjct: 431 NTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEE 267
>28905
Length = 425
Score = 260 bits (664), Expect(2) = 2e-70, Method: Compositional matrix adjust.
Identities = 124/129 (96%), Positives = 126/129 (97%), Gaps = 1/129 (0%)
Frame = -1
Query: 253 LAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLT 312
+AVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLT
Sbjct: 389 VAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLT 210
Query: 313 VAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNST 372
VAA+FRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMS TFIGNST
Sbjct: 209 VAAMFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSGTFIGNST 30
Query: 373 AIQ-ELFKR 380
AIQ LFKR
Sbjct: 29 AIQGRLFKR 3
Score = 23.9 bits (50), Expect(2) = 2e-70, Method: Composition-based stats.
Identities = 9/9 (100%), Positives = 9/9 (100%)
Frame = -2
Query: 242 FPGQLNADL 250
FPGQLNADL
Sbjct: 424 FPGQLNADL 398
>31457
Length = 1530
Score = 250 bits (638), Expect = 1e-66, Method: Compositional matrix adjust.
Identities = 116/119 (97%), Positives = 119/119 (100%)
Frame = +3
Query: 309 RYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFI 368
+YLTVAA+FRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMS+TFI
Sbjct: 234 KYLTVAAMFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSSTFI 413
Query: 369 GNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQD 427
GNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQD
Sbjct: 414 GNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQD 590
>25015
Length = 458
Score = 246 bits (629), Expect = 1e-65, Method: Compositional matrix adjust.
Identities = 115/115 (100%), Positives = 115/115 (100%)
Frame = -3
Query: 20 FWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGKYVPRAVLVDLEPGTMDSVRSG 79
FWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGKYVPRAVLVDLEPGTMDSVRSG
Sbjct: 363 FWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGKYVPRAVLVDLEPGTMDSVRSG 184
Query: 80 PFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQ 134
PFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQ
Sbjct: 183 PFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQ 19
>39157
Length = 488
Score = 233 bits (593), Expect(2) = 4e-65, Method: Compositional matrix adjust.
Identities = 115/127 (90%), Positives = 118/127 (92%), Gaps = 3/127 (2%)
Frame = -1
Query: 1 MREIVHLQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGKYV 60
MREIVHLQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGKYV
Sbjct: 443 MREIVHLQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGKYV 264
Query: 61 PRAVLVDLEPGTMDSVRSG-PFG-QIFRPDNFVFGQSGAGNNWAKGHYTE-GAELVDSVL 117
PRAVLVDLEPGTMDSVRSG PFG +IFRPDNFVFGQSGAGNNW + T+ GAELVDSVL
Sbjct: 263 PRAVLVDLEPGTMDSVRSGSPFGPKIFRPDNFVFGQSGAGNNWGQKDTTQRGAELVDSVL 84
Query: 118 DVVRKEA 124
DVVRK
Sbjct: 83 DVVRKRG 63
Score = 33.9 bits (76), Expect(2) = 4e-65, Method: Compositional matrix adjust.
Identities = 13/13 (100%), Positives = 13/13 (100%)
Frame = -2
Query: 122 KEAESCDCLQGFQ 134
KEAESCDCLQGFQ
Sbjct: 70 KEAESCDCLQGFQ 32
>12457
Length = 781
Score = 209 bits (532), Expect = 2e-54, Method: Compositional matrix adjust.
Identities = 99/239 (41%), Positives = 141/239 (58%)
Frame = -1
Query: 65 LVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEA 124
LVDLEP +D VR+G + Q+F P+ V G+ A NN+A+GHYT G E+VD VLD +RK A
Sbjct: 718 LVDLEPTVVDEVRTGTYRQLFHPEQLVTGKEDAANNYARGHYTIGKEIVDLVLDRIRKLA 539
Query: 125 ESCDCLQGFQXXXXXXXXXXXXXXXXXXXKIREEYPDRIMNTFSVVPSPKVSDTVVEPYN 184
+ C LQGF ++ +Y + F++ P+P+VS VVEPYN
Sbjct: 538 DQCTGLQGFLIFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFAIYPAPQVSTAVVEPYN 359
Query: 185 ATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPG 244
+ L+ H +E++D + +DNEA+YDIC R L + PTY +LN L+ +S +T LRF G
Sbjct: 358 SILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDG 179
Query: 245 QLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAAC 303
LN DL + N+VP+PR+HF + +AP+ S + LTV E+T F+ N M C
Sbjct: 178 ALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLTVAEITNACFEPANQMVKC 2
>05902
Length = 1127
Score = 155 bits (391), Expect = 4e-38, Method: Compositional matrix adjust.
Identities = 91/282 (32%), Positives = 158/282 (56%), Gaps = 12/282 (4%)
Frame = +2
Query: 154 KIREEYPDRIMNTFSVVPS-PKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICF 212
K+ + +P +++ T+SV P+ ++SD VV+PYN+ L++ +L +N D +DN AL I
Sbjct: 74 KLNDRFPKKLIQTYSVFPNVDEISDVVVQPYNSLLTLKRLTQNADCVVVLDNTALNRIAA 253
Query: 213 RTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAP 272
L + TPT+ +N LVS MS TT LR+PG +N DL L +++P PRLHF M G+ P
Sbjct: 254 DRLHIDTPTFAQVNQLVSTVMSTSTTTLRYPGYMNNDLIGLIASLIPTPRLHFLMTGYTP 433
Query: 273 LTSRGS-QQYRALTVPELTQQMFDAKNMMAACDPRHGR----YLTVAAVFRGRMSMKEVD 327
LT+ R TV ++ +++ KNMM + P H + Y+++ + +G + +V
Sbjct: 434 LTTDSQVANVRKTTVLDVMRRLLQPKNMMVST-PVHRQANHCYISILNIIQGEVDPTQVH 610
Query: 328 EQMLNVQNKNSSYFVEWIPNNVKTAVCDIPP---RGLKMSATFIGNSTAIQELFKRISEQ 384
+ + ++ + + F+ W P +++ A+ P ++S + N T+I LF+RI Q
Sbjct: 611 KSLQRIRERKLAQFIPWGPASIQVALSRKSPYVQTAHRVSGLMLANHTSISHLFERILRQ 790
Query: 385 FTAMFRRKAFLHWYTGEGM--DEM-EFTEAESNMNDLVSEYQ 423
+ + +R+AF+ + E + D + EF + + LV EYQ
Sbjct: 791 YDKLRKREAFMDQFKKEAIFKDNLDEFDNSREALQLLVDEYQ 916
>06360
Length = 1896
Score = 137 bits (344), Expect = 1e-32, Method: Compositional matrix adjust.
Identities = 70/179 (39%), Positives = 99/179 (55%), Gaps = 2/179 (1%)
Frame = -1
Query: 1 MREIVHLQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQL--ERINVYYNEATGGK 58
MRE + + GQ G Q+G WE+ EHGI P G D + + N +++E GK
Sbjct: 1710 MRECISVHVGQAGVQMGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGK 1531
Query: 59 YVPRAVLVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLD 118
+VPRAV VDLEP +D VR+G + Q+F P+ V G+ A NN+A+GHYT G E+VD VLD
Sbjct: 1530 HVPRAVFVDLEPTVVDEVRTGTYRQLFHPEQLVTGKEDAANNYARGHYTIGKEIVDLVLD 1351
Query: 119 VVRKEAESCDCLQGFQXXXXXXXXXXXXXXXXXXXKIREEYPDRIMNTFSVVPSPKVSD 177
+RK A+ C LQGF ++ +Y + F++ P+P+VSD
Sbjct: 1350 RIRKLADQCTGLQGFLIFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFAIYPAPQVSD 1174
>03702
Length = 1932
Score = 120 bits (302), Expect = 9e-28, Method: Compositional matrix adjust.
Identities = 59/140 (42%), Positives = 83/140 (59%), Gaps = 1/140 (0%)
Frame = +1
Query: 167 FSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLN 226
F++ P+P+VS VVEPYN+ L+ H +E++D + +DNEA+YDIC R L + P Y +LN
Sbjct: 1501 FAIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPXYTNLN 1680
Query: 227 HLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPG-FAPLTSRGSQQYRALT 285
L+ +S +T LRF G LN DL + N+VP P H PG P+ S + LT
Sbjct: 1681 RLIGQIVSSITASLRFDGALNVDLTEFQTNLVPTP--HPLPPGHLCPVISAEKAYHEQLT 1854
Query: 286 VPELTQQMFDAKNMMAACDP 305
V E+T F+ N + CDP
Sbjct: 1855 VAEVTNACFEPANQLVKCDP 1914
>17215
Length = 632
Score = 81.3 bits (199), Expect = 8e-16, Method: Compositional matrix adjust.
Identities = 36/117 (30%), Positives = 66/117 (56%), Gaps = 8/117 (6%)
Frame = +3
Query: 316 VFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPR--------GLKMSATF 367
++RG + K+V+ + ++ K + FV+W P K + PP ++ +
Sbjct: 6 LYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCM 185
Query: 368 IGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQ 424
+ N+TAI E + R+ +F M+ ++AF+HWY GEGM+E EF+EA ++ L +Y++
Sbjct: 186 LSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEE 356
>19746
Length = 446
Score = 40.0 bits (92), Expect = 0.002, Method: Composition-based stats.
Identities = 24/88 (27%), Positives = 40/88 (45%), Gaps = 2/88 (2%)
Frame = +1
Query: 337 NSSYFVEWIPNNVKTAVCDIPPR--GLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAF 394
+ S F W N+ V + P + SAT + NS + I E+ MF +A+
Sbjct: 49 DPSLFTLWTCPNMAFNVSNQPRAFCAYEKSATLVSNSRSSTRPLDDIMEKAWKMFASRAY 228
Query: 395 LHWYTGEGMDEMEFTEAESNMNDLVSEY 422
+H Y G+ E +F +A + +V+ Y
Sbjct: 229 IHQYVKRGLSEEDFLDAFVTLEQVVASY 312
>29025
Length = 395
Score = 35.8 bits (81), Expect = 0.040, Method: Compositional matrix adjust.
Identities = 16/16 (100%), Positives = 16/16 (100%)
Frame = -3
Query: 412 ESNMNDLVSEYQQYQD 427
ESNMNDLVSEYQQYQD
Sbjct: 354 ESNMNDLVSEYQQYQD 307
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000259925 | hsapiens_gene_ensembl | Tubulin beta
chain (Tubulin beta-5 chain). [Source:Uniprot/SWISSPROT;Acc:P07437]
(444 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
16482 468 e-132
13181 460 e-130
04882 436 e-123
00276 276 9e-75
28905 256 4e-69
31457 248 4e-66
25015 242 2e-64
39157 227 1e-63
12457 209 2e-54
05902 152 3e-37
06360 137 1e-32
03702 120 8e-28
17215 84 1e-16
29025 36 0.037
>16482
Length = 837
Score = 468 bits (1204), Expect = e-132, Method: Compositional matrix adjust.
Identities = 223/246 (90%), Positives = 227/246 (92%)
Frame = +1
Query: 1 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLDRISVYYNEATGGKYV 60
MREIVH+QAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQL+RI+VYYNEATGGKYV
Sbjct: 100 MREIVHMQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGKYV 279
Query: 61 PRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVV 120
PRA+LVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVV
Sbjct: 280 PRAVLVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVV 459
Query: 121 RKEAESCDCLQGFQXXXXXXXXXXXXXXXXXXXKIREEYPDRIMNTFSVVPSPKVSDTVV 180
RKEAESCDCLQGFQ KIREEYPDRIMNTFSVVPSPKVSDTVV
Sbjct: 460 RKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVV 639
Query: 181 EPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCL 240
EPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCL
Sbjct: 640 EPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCL 819
Query: 241 RFPGQL 246
RFPGQL
Sbjct: 820 RFPGQL 837
>13181
Length = 1092
Score = 460 bits (1183), Expect = e-130, Method: Compositional matrix adjust.
Identities = 215/220 (97%), Positives = 219/220 (99%)
Frame = -3
Query: 208 YDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFM 267
YDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFM
Sbjct: 1090 YDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFM 911
Query: 268 PGFAPLTSRGSQQYRALTVPELTQQVFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVD 327
PGFAPLTSRGSQQYRALTVPELTQQ+FDAKNMMAACDPRHGRYLTVAA+FRGRMSMKEVD
Sbjct: 910 PGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAMFRGRMSMKEVD 731
Query: 328 EQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMAVTFIGNSTAIQELFKRISEQFTA 387
EQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKM+ TF+GNSTAIQELFKRISEQFTA
Sbjct: 730 EQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFVGNSTAIQELFKRISEQFTA 551
Query: 388 MFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQD 427
MFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQD
Sbjct: 550 MFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQD 431
>04882
Length = 1136
Score = 436 bits (1122), Expect = e-123, Method: Compositional matrix adjust.
Identities = 204/209 (97%), Positives = 208/209 (99%)
Frame = +2
Query: 219 TPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGS 278
TPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGS
Sbjct: 320 TPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGS 499
Query: 279 QQYRALTVPELTQQVFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNS 338
QQYRALTVPELTQQ+FD+KNMMAACDPRHGRYLTVAA+FRGRMSMKEVDEQMLNVQNKNS
Sbjct: 500 QQYRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNS 679
Query: 339 SYFVEWIPNNVKTAVCDIPPRGLKMAVTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWY 398
SYFVEWIPNNVKTAVCDIPPRGLKM+ TFIGNSTAIQELFKRISEQFTAMFRRKAFLHWY
Sbjct: 680 SYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWY 859
Query: 399 TGEGMDEMEFTEAESNMNDLVSEYQQYQD 427
TGEGMDEMEFTEAESNMNDLVSEYQQYQD
Sbjct: 860 TGEGMDEMEFTEAESNMNDLVSEYQQYQD 946
>00276
Length = 1330
Score = 276 bits (707), Expect = 9e-75, Method: Compositional matrix adjust.
Identities = 133/355 (37%), Positives = 204/355 (57%), Gaps = 8/355 (2%)
Frame = -3
Query: 78 SGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQXXX 137
+G + Q+ P+ V G+ A NN+A+GHYT G ELVD VLD +RK A+ C LQGF
Sbjct: 1328 TGTYRQL-SPEQLVTGKEDAANNYARGHYTIGKELVDLVLDRIRKLADQCTGLQGFLIFH 1152
Query: 138 XXXXXXXXXXXXXXXXKIREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVENTD 197
++ +Y + F + P+P+VS VVEPYN+ L+ H +E++D
Sbjct: 1151 SFGGGTGSGFTSLXMERLSVDYGKKSKLEFXIYPAPQVSTAVVEPYNSILTTHTTLEHSD 972
Query: 198 ETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNM 257
+ +DNEA+YDIC R L + PTY +LN L+ +S +T LRF G LN DL + N+
Sbjct: 971 CAFMVDNEAIYDICRRNLDIERPTYTNLNRLIXQIVSSITASLRFDGALNVDLTEFQTNL 792
Query: 258 VPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQVFDAKNMMAACDPRHGRYLTVAAVF 317
VP+PR+HF + +AP+ S + L V E+T F+ N + CDPRHG+Y+ ++
Sbjct: 791 VPYPRIHFPLATYAPVISAEKAYHEQLXVAEITNACFEPANQLVKCDPRHGKYMACCMLY 612
Query: 318 RGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPR--------GLKMAVTFIG 369
RG + K+V+ + ++ K + FV+W P K + PP ++ AV +
Sbjct: 611 RGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLS 432
Query: 370 NSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQ 424
N+TAI E + R+ +F M+ ++AF+HWY GEGM+E EF+EA ++ L +Y++
Sbjct: 431 NTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEE 267
>28905
Length = 425
Score = 256 bits (654), Expect(2) = 4e-69, Method: Compositional matrix adjust.
Identities = 122/129 (94%), Positives = 126/129 (97%), Gaps = 1/129 (0%)
Frame = -1
Query: 253 LAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQVFDAKNMMAACDPRHGRYLT 312
+AVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQ+FDAKNMMAACDPRHGRYLT
Sbjct: 389 VAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLT 210
Query: 313 VAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMAVTFIGNST 372
VAA+FRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKM+ TFIGNST
Sbjct: 209 VAAMFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSGTFIGNST 30
Query: 373 AIQ-ELFKR 380
AIQ LFKR
Sbjct: 29 AIQGRLFKR 3
Score = 23.9 bits (50), Expect(2) = 4e-69, Method: Composition-based stats.
Identities = 9/9 (100%), Positives = 9/9 (100%)
Frame = -2
Query: 242 FPGQLNADL 250
FPGQLNADL
Sbjct: 424 FPGQLNADL 398
>31457
Length = 1530
Score = 248 bits (632), Expect = 4e-66, Method: Compositional matrix adjust.
Identities = 115/119 (96%), Positives = 118/119 (99%)
Frame = +3
Query: 309 RYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMAVTFI 368
+YLTVAA+FRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKM+ TFI
Sbjct: 234 KYLTVAAMFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSSTFI 413
Query: 369 GNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQD 427
GNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQD
Sbjct: 414 GNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQD 590
>25015
Length = 458
Score = 242 bits (618), Expect = 2e-64, Method: Compositional matrix adjust.
Identities = 112/115 (97%), Positives = 115/115 (100%)
Frame = -3
Query: 20 FWEVISDEHGIDPTGTYHGDSDLQLDRISVYYNEATGGKYVPRAILVDLEPGTMDSVRSG 79
FWEVISDEHGIDPTGTYHGDSDLQL+RI+VYYNEATGGKYVPRA+LVDLEPGTMDSVRSG
Sbjct: 363 FWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGKYVPRAVLVDLEPGTMDSVRSG 184
Query: 80 PFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQ 134
PFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQ
Sbjct: 183 PFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQ 19
>39157
Length = 488
Score = 227 bits (579), Expect(2) = 1e-63, Method: Compositional matrix adjust.
Identities = 111/127 (87%), Positives = 118/127 (92%), Gaps = 3/127 (2%)
Frame = -1
Query: 1 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLDRISVYYNEATGGKYV 60
MREIVH+QAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQL+RI+VYYNEATGGKYV
Sbjct: 443 MREIVHLQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGKYV 264
Query: 61 PRAILVDLEPGTMDSVRSG-PFG-QIFRPDNFVFGQSGAGNNWAKGHYTE-GAELVDSVL 117
PRA+LVDLEPGTMDSVRSG PFG +IFRPDNFVFGQSGAGNNW + T+ GAELVDSVL
Sbjct: 263 PRAVLVDLEPGTMDSVRSGSPFGPKIFRPDNFVFGQSGAGNNWGQKDTTQRGAELVDSVL 84
Query: 118 DVVRKEA 124
DVVRK
Sbjct: 83 DVVRKRG 63
Score = 33.9 bits (76), Expect(2) = 1e-63, Method: Compositional matrix adjust.
Identities = 13/13 (100%), Positives = 13/13 (100%)
Frame = -2
Query: 122 KEAESCDCLQGFQ 134
KEAESCDCLQGFQ
Sbjct: 70 KEAESCDCLQGFQ 32
>12457
Length = 781
Score = 209 bits (532), Expect = 2e-54, Method: Compositional matrix adjust.
Identities = 99/239 (41%), Positives = 141/239 (58%)
Frame = -1
Query: 65 LVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEA 124
LVDLEP +D VR+G + Q+F P+ V G+ A NN+A+GHYT G E+VD VLD +RK A
Sbjct: 718 LVDLEPTVVDEVRTGTYRQLFHPEQLVTGKEDAANNYARGHYTIGKEIVDLVLDRIRKLA 539
Query: 125 ESCDCLQGFQXXXXXXXXXXXXXXXXXXXKIREEYPDRIMNTFSVVPSPKVSDTVVEPYN 184
+ C LQGF ++ +Y + F++ P+P+VS VVEPYN
Sbjct: 538 DQCTGLQGFLIFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFAIYPAPQVSTAVVEPYN 359
Query: 185 ATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPG 244
+ L+ H +E++D + +DNEA+YDIC R L + PTY +LN L+ +S +T LRF G
Sbjct: 358 SILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDG 179
Query: 245 QLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQVFDAKNMMAAC 303
LN DL + N+VP+PR+HF + +AP+ S + LTV E+T F+ N M C
Sbjct: 178 ALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLTVAEITNACFEPANQMVKC 2
>05902
Length = 1127
Score = 152 bits (384), Expect = 3e-37, Method: Compositional matrix adjust.
Identities = 90/282 (31%), Positives = 158/282 (56%), Gaps = 12/282 (4%)
Frame = +2
Query: 154 KIREEYPDRIMNTFSVVPS-PKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICF 212
K+ + +P +++ T+SV P+ ++SD VV+PYN+ L++ +L +N D +DN AL I
Sbjct: 74 KLNDRFPKKLIQTYSVFPNVDEISDVVVQPYNSLLTLKRLTQNADCVVVLDNTALNRIAA 253
Query: 213 RTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAP 272
L + TPT+ +N LVS MS TT LR+PG +N DL L +++P PRLHF M G+ P
Sbjct: 254 DRLHIDTPTFAQVNQLVSTVMSTSTTTLRYPGYMNNDLIGLIASLIPTPRLHFLMTGYTP 433
Query: 273 LTSRGS-QQYRALTVPELTQQVFDAKNMMAACDPRHGR----YLTVAAVFRGRMSMKEVD 327
LT+ R TV ++ +++ KNMM + P H + Y+++ + +G + +V
Sbjct: 434 LTTDSQVANVRKTTVLDVMRRLLQPKNMMVST-PVHRQANHCYISILNIIQGEVDPTQVH 610
Query: 328 EQMLNVQNKNSSYFVEWIPNNVKTAVCDIPP---RGLKMAVTFIGNSTAIQELFKRISEQ 384
+ + ++ + + F+ W P +++ A+ P +++ + N T+I LF+RI Q
Sbjct: 611 KSLQRIRERKLAQFIPWGPASIQVALSRKSPYVQTAHRVSGLMLANHTSISHLFERILRQ 790
Query: 385 FTAMFRRKAFLHWYTGEGM--DEM-EFTEAESNMNDLVSEYQ 423
+ + +R+AF+ + E + D + EF + + LV EYQ
Sbjct: 791 YDKLRKREAFMDQFKKEAIFKDNLDEFDNSREALQLLVDEYQ 916
>06360
Length = 1896
Score = 137 bits (344), Expect = 1e-32, Method: Compositional matrix adjust.
Identities = 69/179 (38%), Positives = 99/179 (55%), Gaps = 2/179 (1%)
Frame = -1
Query: 1 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQL--DRISVYYNEATGGK 58
MRE + + GQ G Q+G WE+ EHGI P G D + D + +++E GK
Sbjct: 1710 MRECISVHVGQAGVQMGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGK 1531
Query: 59 YVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLD 118
+VPRA+ VDLEP +D VR+G + Q+F P+ V G+ A NN+A+GHYT G E+VD VLD
Sbjct: 1530 HVPRAVFVDLEPTVVDEVRTGTYRQLFHPEQLVTGKEDAANNYARGHYTIGKEIVDLVLD 1351
Query: 119 VVRKEAESCDCLQGFQXXXXXXXXXXXXXXXXXXXKIREEYPDRIMNTFSVVPSPKVSD 177
+RK A+ C LQGF ++ +Y + F++ P+P+VSD
Sbjct: 1350 RIRKLADQCTGLQGFLIFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFAIYPAPQVSD 1174
>03702
Length = 1932
Score = 120 bits (302), Expect = 8e-28, Method: Compositional matrix adjust.
Identities = 59/140 (42%), Positives = 83/140 (59%), Gaps = 1/140 (0%)
Frame = +1
Query: 167 FSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLN 226
F++ P+P+VS VVEPYN+ L+ H +E++D + +DNEA+YDIC R L + P Y +LN
Sbjct: 1501 FAIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPXYTNLN 1680
Query: 227 HLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPG-FAPLTSRGSQQYRALT 285
L+ +S +T LRF G LN DL + N+VP P H PG P+ S + LT
Sbjct: 1681 RLIGQIVSSITASLRFDGALNVDLTEFQTNLVPTP--HPLPPGHLCPVISAEKAYHEQLT 1854
Query: 286 VPELTQQVFDAKNMMAACDP 305
V E+T F+ N + CDP
Sbjct: 1855 VAEVTNACFEPANQLVKCDP 1914
>17215
Length = 632
Score = 84.0 bits (206), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 38/117 (32%), Positives = 67/117 (57%), Gaps = 8/117 (6%)
Frame = +3
Query: 316 VFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPP--------RGLKMAVTF 367
++RG + K+V+ + ++ K + FV+W P K + PP ++ AV
Sbjct: 6 LYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCM 185
Query: 368 IGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQ 424
+ N+TAI E + R+ +F M+ ++AF+HWY GEGM+E EF+EA ++ L +Y++
Sbjct: 186 LSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEE 356
>29025
Length = 395
Score = 35.8 bits (81), Expect = 0.037, Method: Compositional matrix adjust.
Identities = 16/16 (100%), Positives = 16/16 (100%)
Frame = -3
Query: 412 ESNMNDLVSEYQQYQD 427
ESNMNDLVSEYQQYQD
Sbjct: 354 ESNMNDLVSEYQQYQD 307
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000264071 | hsapiens_gene_ensembl | Tubulin beta-4
chain (Tubulin 5 beta). [Source:Uniprot/SWISSPROT;Acc:P04350]
(444 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
16482 469 e-132
13181 459 e-129
04882 436 e-122
00276 275 3e-74
28905 255 8e-69
31457 244 4e-65
25015 243 9e-65
39157 229 3e-64
12457 208 3e-54
05902 155 3e-38
06360 134 8e-32
03702 120 2e-27
17215 83 2e-16
29025 36 0.038
>16482
Length = 837
Score = 469 bits (1206), Expect = e-132, Method: Compositional matrix adjust.
Identities = 223/246 (90%), Positives = 226/246 (91%)
Frame = +1
Query: 1 MREIVHLQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGNYV 60
MREIVH+QAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGG YV
Sbjct: 100 MREIVHMQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGKYV 279
Query: 61 PRAVLVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDAVLDVV 120
PRAVLVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVD+VLDVV
Sbjct: 280 PRAVLVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVV 459
Query: 121 RKEAESCDCLQGFQXXXXXXXXXXXXXXXXXXXKIREEFPDRIMNTFSVVPSPKVSDTVV 180
RKEAESCDCLQGFQ KIREE+PDRIMNTFSVVPSPKVSDTVV
Sbjct: 460 RKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVV 639
Query: 181 EPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCL 240
EPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCL
Sbjct: 640 EPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCL 819
Query: 241 RFPGQL 246
RFPGQL
Sbjct: 820 RFPGQL 837
>13181
Length = 1092
Score = 459 bits (1180), Expect = e-129, Method: Compositional matrix adjust.
Identities = 215/220 (97%), Positives = 220/220 (100%)
Frame = -3
Query: 208 YDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFM 267
YDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFM
Sbjct: 1090 YDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFM 911
Query: 268 PGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVD 327
PGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAA+FRGRMSMKEVD
Sbjct: 910 PGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAMFRGRMSMKEVD 731
Query: 328 EQMLSVQSKNSSYFVEWIPNNVKTAVCDIPPRGLKMAATFIGNSTAIQELFKRISEQFTA 387
EQML+VQ+KNSSYFVEWIPNNVKTAVCDIPPRGLKM+ATF+GNSTAIQELFKRISEQFTA
Sbjct: 730 EQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFVGNSTAIQELFKRISEQFTA 551
Query: 388 MFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQD 427
MFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQD
Sbjct: 550 MFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQD 431
>04882
Length = 1136
Score = 436 bits (1120), Expect = e-122, Method: Compositional matrix adjust.
Identities = 204/209 (97%), Positives = 209/209 (100%)
Frame = +2
Query: 219 TPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGS 278
TPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGS
Sbjct: 320 TPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGS 499
Query: 279 QQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVDEQMLSVQSKNS 338
QQYRALTVPELTQQMFD+KNMMAACDPRHGRYLTVAA+FRGRMSMKEVDEQML+VQ+KNS
Sbjct: 500 QQYRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNS 679
Query: 339 SYFVEWIPNNVKTAVCDIPPRGLKMAATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWY 398
SYFVEWIPNNVKTAVCDIPPRGLKM+ATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWY
Sbjct: 680 SYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWY 859
Query: 399 TGEGMDEMEFTEAESNMNDLVSEYQQYQD 427
TGEGMDEMEFTEAESNMNDLVSEYQQYQD
Sbjct: 860 TGEGMDEMEFTEAESNMNDLVSEYQQYQD 946
>00276
Length = 1330
Score = 275 bits (702), Expect = 3e-74, Method: Compositional matrix adjust.
Identities = 131/355 (36%), Positives = 205/355 (57%), Gaps = 8/355 (2%)
Frame = -3
Query: 78 SGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDAVLDVVRKEAESCDCLQGFQXXX 137
+G + Q+ P+ V G+ A NN+A+GHYT G ELVD VLD +RK A+ C LQGF
Sbjct: 1328 TGTYRQL-SPEQLVTGKEDAANNYARGHYTIGKELVDLVLDRIRKLADQCTGLQGFLIFH 1152
Query: 138 XXXXXXXXXXXXXXXXKIREEFPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVENTD 197
++ ++ + F + P+P+VS VVEPYN+ L+ H +E++D
Sbjct: 1151 SFGGGTGSGFTSLXMERLSVDYGKKSKLEFXIYPAPQVSTAVVEPYNSILTTHTTLEHSD 972
Query: 198 ETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNM 257
+ +DNEA+YDIC R L + PTY +LN L+ +S +T LRF G LN DL + N+
Sbjct: 971 CAFMVDNEAIYDICRRNLDIERPTYTNLNRLIXQIVSSITASLRFDGALNVDLTEFQTNL 792
Query: 258 VPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAVF 317
VP+PR+HF + +AP+ S + L V E+T F+ N + CDPRHG+Y+ ++
Sbjct: 791 VPYPRIHFPLATYAPVISAEKAYHEQLXVAEITNACFEPANQLVKCDPRHGKYMACCMLY 612
Query: 318 RGRMSMKEVDEQMLSVQSKNSSYFVEWIPNNVKTAVCDIPPR--------GLKMAATFIG 369
RG + K+V+ + ++++K + FV+W P K + PP ++ A +
Sbjct: 611 RGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLS 432
Query: 370 NSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQ 424
N+TAI E + R+ +F M+ ++AF+HWY GEGM+E EF+EA ++ L +Y++
Sbjct: 431 NTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEE 267
>28905
Length = 425
Score = 255 bits (651), Expect(2) = 8e-69, Method: Compositional matrix adjust.
Identities = 121/129 (93%), Positives = 126/129 (97%), Gaps = 1/129 (0%)
Frame = -1
Query: 253 LAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLT 312
+AVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLT
Sbjct: 389 VAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLT 210
Query: 313 VAAVFRGRMSMKEVDEQMLSVQSKNSSYFVEWIPNNVKTAVCDIPPRGLKMAATFIGNST 372
VAA+FRGRMSMKEVDEQML+VQ+KNSSYFVEWIPNNVKTAVCDIPPRGLKM+ TFIGNST
Sbjct: 209 VAAMFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSGTFIGNST 30
Query: 373 AIQ-ELFKR 380
AIQ LFKR
Sbjct: 29 AIQGRLFKR 3
Score = 23.9 bits (50), Expect(2) = 8e-69, Method: Composition-based stats.
Identities = 9/9 (100%), Positives = 9/9 (100%)
Frame = -2
Query: 242 FPGQLNADL 250
FPGQLNADL
Sbjct: 424 FPGQLNADL 398
>31457
Length = 1530
Score = 244 bits (624), Expect = 4e-65, Method: Compositional matrix adjust.
Identities = 113/119 (94%), Positives = 119/119 (100%)
Frame = +3
Query: 309 RYLTVAAVFRGRMSMKEVDEQMLSVQSKNSSYFVEWIPNNVKTAVCDIPPRGLKMAATFI 368
+YLTVAA+FRGRMSMKEVDEQML+VQ+KNSSYFVEWIPNNVKTAVCDIPPRGLKM++TFI
Sbjct: 234 KYLTVAAMFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSSTFI 413
Query: 369 GNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQD 427
GNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQD
Sbjct: 414 GNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQD 590
>25015
Length = 458
Score = 243 bits (621), Expect = 9e-65, Method: Compositional matrix adjust.
Identities = 113/115 (98%), Positives = 114/115 (99%)
Frame = -3
Query: 20 FWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGNYVPRAVLVDLEPGTMDSVRSG 79
FWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGG YVPRAVLVDLEPGTMDSVRSG
Sbjct: 363 FWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGKYVPRAVLVDLEPGTMDSVRSG 184
Query: 80 PFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDAVLDVVRKEAESCDCLQGFQ 134
PFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVD+VLDVVRKEAESCDCLQGFQ
Sbjct: 183 PFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQ 19
>39157
Length = 488
Score = 229 bits (584), Expect(2) = 3e-64, Method: Compositional matrix adjust.
Identities = 113/127 (88%), Positives = 117/127 (92%), Gaps = 3/127 (2%)
Frame = -1
Query: 1 MREIVHLQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGNYV 60
MREIVHLQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGG YV
Sbjct: 443 MREIVHLQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGKYV 264
Query: 61 PRAVLVDLEPGTMDSVRSG-PFG-QIFRPDNFVFGQSGAGNNWAKGHYTE-GAELVDAVL 117
PRAVLVDLEPGTMDSVRSG PFG +IFRPDNFVFGQSGAGNNW + T+ GAELVD+VL
Sbjct: 263 PRAVLVDLEPGTMDSVRSGSPFGPKIFRPDNFVFGQSGAGNNWGQKDTTQRGAELVDSVL 84
Query: 118 DVVRKEA 124
DVVRK
Sbjct: 83 DVVRKRG 63
Score = 33.9 bits (76), Expect(2) = 3e-64, Method: Compositional matrix adjust.
Identities = 13/13 (100%), Positives = 13/13 (100%)
Frame = -2
Query: 122 KEAESCDCLQGFQ 134
KEAESCDCLQGFQ
Sbjct: 70 KEAESCDCLQGFQ 32
>12457
Length = 781
Score = 208 bits (530), Expect = 3e-54, Method: Compositional matrix adjust.
Identities = 98/239 (41%), Positives = 141/239 (58%)
Frame = -1
Query: 65 LVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDAVLDVVRKEA 124
LVDLEP +D VR+G + Q+F P+ V G+ A NN+A+GHYT G E+VD VLD +RK A
Sbjct: 718 LVDLEPTVVDEVRTGTYRQLFHPEQLVTGKEDAANNYARGHYTIGKEIVDLVLDRIRKLA 539
Query: 125 ESCDCLQGFQXXXXXXXXXXXXXXXXXXXKIREEFPDRIMNTFSVVPSPKVSDTVVEPYN 184
+ C LQGF ++ ++ + F++ P+P+VS VVEPYN
Sbjct: 538 DQCTGLQGFLIFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFAIYPAPQVSTAVVEPYN 359
Query: 185 ATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPG 244
+ L+ H +E++D + +DNEA+YDIC R L + PTY +LN L+ +S +T LRF G
Sbjct: 358 SILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDG 179
Query: 245 QLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAAC 303
LN DL + N+VP+PR+HF + +AP+ S + LTV E+T F+ N M C
Sbjct: 178 ALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLTVAEITNACFEPANQMVKC 2
>05902
Length = 1127
Score = 155 bits (393), Expect = 3e-38, Method: Compositional matrix adjust.
Identities = 91/282 (32%), Positives = 158/282 (56%), Gaps = 12/282 (4%)
Frame = +2
Query: 154 KIREEFPDRIMNTFSVVPS-PKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICF 212
K+ + FP +++ T+SV P+ ++SD VV+PYN+ L++ +L +N D +DN AL I
Sbjct: 74 KLNDRFPKKLIQTYSVFPNVDEISDVVVQPYNSLLTLKRLTQNADCVVVLDNTALNRIAA 253
Query: 213 RTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAP 272
L + TPT+ +N LVS MS TT LR+PG +N DL L +++P PRLHF M G+ P
Sbjct: 254 DRLHIDTPTFAQVNQLVSTVMSTSTTTLRYPGYMNNDLIGLIASLIPTPRLHFLMTGYTP 433
Query: 273 LTSRGS-QQYRALTVPELTQQMFDAKNMMAACDPRHGR----YLTVAAVFRGRMSMKEVD 327
LT+ R TV ++ +++ KNMM + P H + Y+++ + +G + +V
Sbjct: 434 LTTDSQVANVRKTTVLDVMRRLLQPKNMMVST-PVHRQANHCYISILNIIQGEVDPTQVH 610
Query: 328 EQMLSVQSKNSSYFVEWIPNNVKTAVCDIPP---RGLKMAATFIGNSTAIQELFKRISEQ 384
+ + ++ + + F+ W P +++ A+ P +++ + N T+I LF+RI Q
Sbjct: 611 KSLQRIRERKLAQFIPWGPASIQVALSRKSPYVQTAHRVSGLMLANHTSISHLFERILRQ 790
Query: 385 FTAMFRRKAFLHWYTGEGM--DEM-EFTEAESNMNDLVSEYQ 423
+ + +R+AF+ + E + D + EF + + LV EYQ
Sbjct: 791 YDKLRKREAFMDQFKKEAIFKDNLDEFDNSREALQLLVDEYQ 916
>06360
Length = 1896
Score = 134 bits (337), Expect = 8e-32, Method: Compositional matrix adjust.
Identities = 68/179 (37%), Positives = 98/179 (54%), Gaps = 2/179 (1%)
Frame = -1
Query: 1 MREIVHLQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQL--ERINVYYNEATGGN 58
MRE + + GQ G Q+G WE+ EHGI P G D + + N +++E G
Sbjct: 1710 MRECISVHVGQAGVQMGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGK 1531
Query: 59 YVPRAVLVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDAVLD 118
+VPRAV VDLEP +D VR+G + Q+F P+ V G+ A NN+A+GHYT G E+VD VLD
Sbjct: 1530 HVPRAVFVDLEPTVVDEVRTGTYRQLFHPEQLVTGKEDAANNYARGHYTIGKEIVDLVLD 1351
Query: 119 VVRKEAESCDCLQGFQXXXXXXXXXXXXXXXXXXXKIREEFPDRIMNTFSVVPSPKVSD 177
+RK A+ C LQGF ++ ++ + F++ P+P+VSD
Sbjct: 1350 RIRKLADQCTGLQGFLIFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFAIYPAPQVSD 1174
>03702
Length = 1932
Score = 120 bits (300), Expect = 2e-27, Method: Compositional matrix adjust.
Identities = 59/140 (42%), Positives = 83/140 (59%), Gaps = 1/140 (0%)
Frame = +1
Query: 167 FSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLN 226
F++ P+P+VS VVEPYN+ L+ H +E++D + +DNEA+YDIC R L + P Y +LN
Sbjct: 1501 FAIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPXYTNLN 1680
Query: 227 HLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPG-FAPLTSRGSQQYRALT 285
L+ +S +T LRF G LN DL + N+VP P H PG P+ S + LT
Sbjct: 1681 RLIGQIVSSITASLRFDGALNVDLTEFQTNLVPTP--HPLPPGHLCPVISAEKAYHEQLT 1854
Query: 286 VPELTQQMFDAKNMMAACDP 305
V E+T F+ N + CDP
Sbjct: 1855 VAEVTNACFEPANQLVKCDP 1914
>17215
Length = 632
Score = 83.2 bits (204), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 37/117 (31%), Positives = 68/117 (58%), Gaps = 8/117 (6%)
Frame = +3
Query: 316 VFRGRMSMKEVDEQMLSVQSKNSSYFVEWIPNNVKTAVCDIPPR--------GLKMAATF 367
++RG + K+V+ + ++++K + FV+W P K + PP ++ A
Sbjct: 6 LYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCM 185
Query: 368 IGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQ 424
+ N+TAI E + R+ +F M+ ++AF+HWY GEGM+E EF+EA ++ L +Y++
Sbjct: 186 LSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEE 356
>29025
Length = 395
Score = 35.8 bits (81), Expect = 0.038, Method: Compositional matrix adjust.
Identities = 16/16 (100%), Positives = 16/16 (100%)
Frame = -3
Query: 412 ESNMNDLVSEYQQYQD 427
ESNMNDLVSEYQQYQD
Sbjct: 354 ESNMNDLVSEYQQYQD 307
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000383302 | hsapiens_gene_ensembl | Tubulin beta
chain (Tubulin beta-5 chain). [Source:Uniprot/SWISSPROT;Acc:P07437]
(372 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
13181 460 e-130
04882 437 e-123
16482 321 3e-88
00276 277 6e-75
28905 256 6e-69
31457 248 3e-66
12457 198 3e-51
05902 152 2e-37
25015 136 2e-32
03702 120 7e-28
39157 80 7e-20
17215 84 9e-17
06360 80 2e-15
29025 36 0.031
>13181
Length = 1092
Score = 460 bits (1183), Expect = e-130, Method: Compositional matrix adjust.
Identities = 215/220 (97%), Positives = 219/220 (99%)
Frame = -3
Query: 136 YDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFM 195
YDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFM
Sbjct: 1090 YDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFM 911
Query: 196 PGFAPLTSRGSQQYRALTVPELTQQVFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVD 255
PGFAPLTSRGSQQYRALTVPELTQQ+FDAKNMMAACDPRHGRYLTVAA+FRGRMSMKEVD
Sbjct: 910 PGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAMFRGRMSMKEVD 731
Query: 256 EQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMAVTFIGNSTAIQELFKRISEQFTA 315
EQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKM+ TF+GNSTAIQELFKRISEQFTA
Sbjct: 730 EQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFVGNSTAIQELFKRISEQFTA 551
Query: 316 MFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQD 355
MFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQD
Sbjct: 550 MFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQD 431
>04882
Length = 1136
Score = 437 bits (1123), Expect = e-123, Method: Compositional matrix adjust.
Identities = 204/209 (97%), Positives = 208/209 (99%)
Frame = +2
Query: 147 TPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGS 206
TPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGS
Sbjct: 320 TPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGS 499
Query: 207 QQYRALTVPELTQQVFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNS 266
QQYRALTVPELTQQ+FD+KNMMAACDPRHGRYLTVAA+FRGRMSMKEVDEQMLNVQNKNS
Sbjct: 500 QQYRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNS 679
Query: 267 SYFVEWIPNNVKTAVCDIPPRGLKMAVTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWY 326
SYFVEWIPNNVKTAVCDIPPRGLKM+ TFIGNSTAIQELFKRISEQFTAMFRRKAFLHWY
Sbjct: 680 SYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWY 859
Query: 327 TGEGMDEMEFTEAESNMNDLVSEYQQYQD 355
TGEGMDEMEFTEAESNMNDLVSEYQQYQD
Sbjct: 860 TGEGMDEMEFTEAESNMNDLVSEYQQYQD 946
>16482
Length = 837
Score = 321 bits (823), Expect = 3e-88, Method: Compositional matrix adjust.
Identities = 155/174 (89%), Positives = 155/174 (89%)
Frame = +1
Query: 1 MDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQG 60
MDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQG
Sbjct: 316 MDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQG 495
Query: 61 FQXXXXXXXXXXXXXXXXXXXKIREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQL 120
FQ KIREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQL
Sbjct: 496 FQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQL 675
Query: 121 VENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQL 174
VENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQL
Sbjct: 676 VENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQL 837
>00276
Length = 1330
Score = 277 bits (708), Expect = 6e-75, Method: Compositional matrix adjust.
Identities = 133/355 (37%), Positives = 204/355 (57%), Gaps = 8/355 (2%)
Frame = -3
Query: 6 SGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQXXX 65
+G + Q+ P+ V G+ A NN+A+GHYT G ELVD VLD +RK A+ C LQGF
Sbjct: 1328 TGTYRQL-SPEQLVTGKEDAANNYARGHYTIGKELVDLVLDRIRKLADQCTGLQGFLIFH 1152
Query: 66 XXXXXXXXXXXXXXXXKIREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVENTD 125
++ +Y + F + P+P+VS VVEPYN+ L+ H +E++D
Sbjct: 1151 SFGGGTGSGFTSLXMERLSVDYGKKSKLEFXIYPAPQVSTAVVEPYNSILTTHTTLEHSD 972
Query: 126 ETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNM 185
+ +DNEA+YDIC R L + PTY +LN L+ +S +T LRF G LN DL + N+
Sbjct: 971 CAFMVDNEAIYDICRRNLDIERPTYTNLNRLIXQIVSSITASLRFDGALNVDLTEFQTNL 792
Query: 186 VPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQVFDAKNMMAACDPRHGRYLTVAAVF 245
VP+PR+HF + +AP+ S + L V E+T F+ N + CDPRHG+Y+ ++
Sbjct: 791 VPYPRIHFPLATYAPVISAEKAYHEQLXVAEITNACFEPANQLVKCDPRHGKYMACCMLY 612
Query: 246 RGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPR--------GLKMAVTFIG 297
RG + K+V+ + ++ K + FV+W P K + PP ++ AV +
Sbjct: 611 RGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLS 432
Query: 298 NSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQ 352
N+TAI E + R+ +F M+ ++AF+HWY GEGM+E EF+EA ++ L +Y++
Sbjct: 431 NTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEE 267
>28905
Length = 425
Score = 256 bits (654), Expect(2) = 6e-69, Method: Compositional matrix adjust.
Identities = 122/129 (94%), Positives = 126/129 (97%), Gaps = 1/129 (0%)
Frame = -1
Query: 181 LAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQVFDAKNMMAACDPRHGRYLT 240
+AVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQ+FDAKNMMAACDPRHGRYLT
Sbjct: 389 VAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLT 210
Query: 241 VAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMAVTFIGNST 300
VAA+FRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKM+ TFIGNST
Sbjct: 209 VAAMFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSGTFIGNST 30
Query: 301 AIQ-ELFKR 308
AIQ LFKR
Sbjct: 29 AIQGRLFKR 3
Score = 23.1 bits (48), Expect(2) = 6e-69, Method: Compositional matrix adjust.
Identities = 9/9 (100%), Positives = 9/9 (100%)
Frame = -2
Query: 170 FPGQLNADL 178
FPGQLNADL
Sbjct: 424 FPGQLNADL 398
>31457
Length = 1530
Score = 248 bits (633), Expect = 3e-66, Method: Compositional matrix adjust.
Identities = 115/119 (96%), Positives = 118/119 (99%)
Frame = +3
Query: 237 RYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMAVTFI 296
+YLTVAA+FRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKM+ TFI
Sbjct: 234 KYLTVAAMFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSSTFI 413
Query: 297 GNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQD 355
GNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQD
Sbjct: 414 GNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQD 590
>12457
Length = 781
Score = 198 bits (503), Expect = 3e-51, Method: Compositional matrix adjust.
Identities = 93/231 (40%), Positives = 135/231 (58%)
Frame = -1
Query: 1 MDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQG 60
+D VR+G + Q+F P+ V G+ A NN+A+GHYT G E+VD VLD +RK A+ C LQG
Sbjct: 694 VDEVRTGTYRQLFHPEQLVTGKEDAANNYARGHYTIGKEIVDLVLDRIRKLADQCTGLQG 515
Query: 61 FQXXXXXXXXXXXXXXXXXXXKIREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQL 120
F ++ +Y + F++ P+P+VS VVEPYN+ L+ H
Sbjct: 514 FLIFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFAIYPAPQVSTAVVEPYNSILTTHTT 335
Query: 121 VENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRK 180
+E++D + +DNEA+YDIC R L + PTY +LN L+ +S +T LRF G LN DL +
Sbjct: 334 LEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTE 155
Query: 181 LAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQVFDAKNMMAAC 231
N+VP+PR+HF + +AP+ S + LTV E+T F+ N M C
Sbjct: 154 FQTNLVPYPRIHFPLATYAPVISAEKAYHEQLTVAEITNACFEPANQMVKC 2
>05902
Length = 1127
Score = 152 bits (384), Expect = 2e-37, Method: Compositional matrix adjust.
Identities = 90/282 (31%), Positives = 158/282 (56%), Gaps = 12/282 (4%)
Frame = +2
Query: 82 KIREEYPDRIMNTFSVVPS-PKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICF 140
K+ + +P +++ T+SV P+ ++SD VV+PYN+ L++ +L +N D +DN AL I
Sbjct: 74 KLNDRFPKKLIQTYSVFPNVDEISDVVVQPYNSLLTLKRLTQNADCVVVLDNTALNRIAA 253
Query: 141 RTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAP 200
L + TPT+ +N LVS MS TT LR+PG +N DL L +++P PRLHF M G+ P
Sbjct: 254 DRLHIDTPTFAQVNQLVSTVMSTSTTTLRYPGYMNNDLIGLIASLIPTPRLHFLMTGYTP 433
Query: 201 LTSRGS-QQYRALTVPELTQQVFDAKNMMAACDPRHGR----YLTVAAVFRGRMSMKEVD 255
LT+ R TV ++ +++ KNMM + P H + Y+++ + +G + +V
Sbjct: 434 LTTDSQVANVRKTTVLDVMRRLLQPKNMMVST-PVHRQANHCYISILNIIQGEVDPTQVH 610
Query: 256 EQMLNVQNKNSSYFVEWIPNNVKTAVCDIPP---RGLKMAVTFIGNSTAIQELFKRISEQ 312
+ + ++ + + F+ W P +++ A+ P +++ + N T+I LF+RI Q
Sbjct: 611 KSLQRIRERKLAQFIPWGPASIQVALSRKSPYVQTAHRVSGLMLANHTSISHLFERILRQ 790
Query: 313 FTAMFRRKAFLHWYTGEGM--DEM-EFTEAESNMNDLVSEYQ 351
+ + +R+AF+ + E + D + EF + + LV EYQ
Sbjct: 791 YDKLRKREAFMDQFKKEAIFKDNLDEFDNSREALQLLVDEYQ 916
>25015
Length = 458
Score = 136 bits (342), Expect = 2e-32, Method: Compositional matrix adjust.
Identities = 62/62 (100%), Positives = 62/62 (100%)
Frame = -3
Query: 1 MDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQG 60
MDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQG
Sbjct: 204 MDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQG 25
Query: 61 FQ 62
FQ
Sbjct: 24 FQ 19
>03702
Length = 1932
Score = 120 bits (302), Expect = 7e-28, Method: Compositional matrix adjust.
Identities = 59/140 (42%), Positives = 83/140 (59%), Gaps = 1/140 (0%)
Frame = +1
Query: 95 FSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLN 154
F++ P+P+VS VVEPYN+ L+ H +E++D + +DNEA+YDIC R L + P Y +LN
Sbjct: 1501 FAIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPXYTNLN 1680
Query: 155 HLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPG-FAPLTSRGSQQYRALT 213
L+ +S +T LRF G LN DL + N+VP P H PG P+ S + LT
Sbjct: 1681 RLIGQIVSSITASLRFDGALNVDLTEFQTNLVPTP--HPLPPGHLCPVISAEKAYHEQLT 1854
Query: 214 VPELTQQVFDAKNMMAACDP 233
V E+T F+ N + CDP
Sbjct: 1855 VAEVTNACFEPANQLVKCDP 1914
>39157
Length = 488
Score = 80.5 bits (197), Expect(2) = 7e-20, Method: Compositional matrix adjust.
Identities = 43/55 (78%), Positives = 46/55 (83%), Gaps = 3/55 (5%)
Frame = -1
Query: 1 MDSVRSG-PFG-QIFRPDNFVFGQSGAGNNWAKGHYTE-GAELVDSVLDVVRKEA 52
MDSVRSG PFG +IFRPDNFVFGQSGAGNNW + T+ GAELVDSVLDVVRK
Sbjct: 227 MDSVRSGSPFGPKIFRPDNFVFGQSGAGNNWGQKDTTQRGAELVDSVLDVVRKRG 63
Score = 34.3 bits (77), Expect(2) = 7e-20, Method: Compositional matrix adjust.
Identities = 13/13 (100%), Positives = 13/13 (100%)
Frame = -2
Query: 50 KEAESCDCLQGFQ 62
KEAESCDCLQGFQ
Sbjct: 70 KEAESCDCLQGFQ 32
>17215
Length = 632
Score = 84.0 bits (206), Expect = 9e-17, Method: Compositional matrix adjust.
Identities = 38/117 (32%), Positives = 67/117 (57%), Gaps = 8/117 (6%)
Frame = +3
Query: 244 VFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPP--------RGLKMAVTF 295
++RG + K+V+ + ++ K + FV+W P K + PP ++ AV
Sbjct: 6 LYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCM 185
Query: 296 IGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQ 352
+ N+TAI E + R+ +F M+ ++AF+HWY GEGM+E EF+EA ++ L +Y++
Sbjct: 186 LSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEE 356
>06360
Length = 1896
Score = 79.7 bits (195), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 39/105 (37%), Positives = 58/105 (55%)
Frame = -1
Query: 1 MDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQG 60
+D VR+G + Q+F P+ V G+ A NN+A+GHYT G E+VD VLD +RK A+ C LQG
Sbjct: 1488 VDEVRTGTYRQLFHPEQLVTGKEDAANNYARGHYTIGKEIVDLVLDRIRKLADQCTGLQG 1309
Query: 61 FQXXXXXXXXXXXXXXXXXXXKIREEYPDRIMNTFSVVPSPKVSD 105
F ++ +Y + F++ P+P+VSD
Sbjct: 1308 FLIFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFAIYPAPQVSD 1174
>29025
Length = 395
Score = 35.8 bits (81), Expect = 0.031, Method: Compositional matrix adjust.
Identities = 16/16 (100%), Positives = 16/16 (100%)
Frame = -3
Query: 340 ESNMNDLVSEYQQYQD 355
ESNMNDLVSEYQQYQD
Sbjct: 354 ESNMNDLVSEYQQYQD 307
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000383304 | hsapiens_gene_ensembl | Tubulin beta
chain (Tubulin beta-5 chain). [Source:Uniprot/SWISSPROT;Acc:P07437]
(372 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
13181 460 e-130
04882 437 e-123
16482 321 3e-88
00276 277 6e-75
28905 256 6e-69
31457 248 3e-66
12457 198 3e-51
05902 152 2e-37
25015 136 2e-32
03702 120 7e-28
39157 80 7e-20
17215 84 9e-17
06360 80 2e-15
29025 36 0.031
>13181
Length = 1092
Score = 460 bits (1183), Expect = e-130, Method: Compositional matrix adjust.
Identities = 215/220 (97%), Positives = 219/220 (99%)
Frame = -3
Query: 136 YDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFM 195
YDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFM
Sbjct: 1090 YDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFM 911
Query: 196 PGFAPLTSRGSQQYRALTVPELTQQVFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVD 255
PGFAPLTSRGSQQYRALTVPELTQQ+FDAKNMMAACDPRHGRYLTVAA+FRGRMSMKEVD
Sbjct: 910 PGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAMFRGRMSMKEVD 731
Query: 256 EQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMAVTFIGNSTAIQELFKRISEQFTA 315
EQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKM+ TF+GNSTAIQELFKRISEQFTA
Sbjct: 730 EQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFVGNSTAIQELFKRISEQFTA 551
Query: 316 MFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQD 355
MFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQD
Sbjct: 550 MFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQD 431
>04882
Length = 1136
Score = 437 bits (1123), Expect = e-123, Method: Compositional matrix adjust.
Identities = 204/209 (97%), Positives = 208/209 (99%)
Frame = +2
Query: 147 TPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGS 206
TPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGS
Sbjct: 320 TPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGS 499
Query: 207 QQYRALTVPELTQQVFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNS 266
QQYRALTVPELTQQ+FD+KNMMAACDPRHGRYLTVAA+FRGRMSMKEVDEQMLNVQNKNS
Sbjct: 500 QQYRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNS 679
Query: 267 SYFVEWIPNNVKTAVCDIPPRGLKMAVTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWY 326
SYFVEWIPNNVKTAVCDIPPRGLKM+ TFIGNSTAIQELFKRISEQFTAMFRRKAFLHWY
Sbjct: 680 SYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWY 859
Query: 327 TGEGMDEMEFTEAESNMNDLVSEYQQYQD 355
TGEGMDEMEFTEAESNMNDLVSEYQQYQD
Sbjct: 860 TGEGMDEMEFTEAESNMNDLVSEYQQYQD 946
>16482
Length = 837
Score = 321 bits (823), Expect = 3e-88, Method: Compositional matrix adjust.
Identities = 155/174 (89%), Positives = 155/174 (89%)
Frame = +1
Query: 1 MDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQG 60
MDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQG
Sbjct: 316 MDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQG 495
Query: 61 FQXXXXXXXXXXXXXXXXXXXKIREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQL 120
FQ KIREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQL
Sbjct: 496 FQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQL 675
Query: 121 VENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQL 174
VENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQL
Sbjct: 676 VENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQL 837
>00276
Length = 1330
Score = 277 bits (708), Expect = 6e-75, Method: Compositional matrix adjust.
Identities = 133/355 (37%), Positives = 204/355 (57%), Gaps = 8/355 (2%)
Frame = -3
Query: 6 SGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQXXX 65
+G + Q+ P+ V G+ A NN+A+GHYT G ELVD VLD +RK A+ C LQGF
Sbjct: 1328 TGTYRQL-SPEQLVTGKEDAANNYARGHYTIGKELVDLVLDRIRKLADQCTGLQGFLIFH 1152
Query: 66 XXXXXXXXXXXXXXXXKIREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVENTD 125
++ +Y + F + P+P+VS VVEPYN+ L+ H +E++D
Sbjct: 1151 SFGGGTGSGFTSLXMERLSVDYGKKSKLEFXIYPAPQVSTAVVEPYNSILTTHTTLEHSD 972
Query: 126 ETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNM 185
+ +DNEA+YDIC R L + PTY +LN L+ +S +T LRF G LN DL + N+
Sbjct: 971 CAFMVDNEAIYDICRRNLDIERPTYTNLNRLIXQIVSSITASLRFDGALNVDLTEFQTNL 792
Query: 186 VPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQVFDAKNMMAACDPRHGRYLTVAAVF 245
VP+PR+HF + +AP+ S + L V E+T F+ N + CDPRHG+Y+ ++
Sbjct: 791 VPYPRIHFPLATYAPVISAEKAYHEQLXVAEITNACFEPANQLVKCDPRHGKYMACCMLY 612
Query: 246 RGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPR--------GLKMAVTFIG 297
RG + K+V+ + ++ K + FV+W P K + PP ++ AV +
Sbjct: 611 RGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLS 432
Query: 298 NSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQ 352
N+TAI E + R+ +F M+ ++AF+HWY GEGM+E EF+EA ++ L +Y++
Sbjct: 431 NTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEE 267
>28905
Length = 425
Score = 256 bits (654), Expect(2) = 6e-69, Method: Compositional matrix adjust.
Identities = 122/129 (94%), Positives = 126/129 (97%), Gaps = 1/129 (0%)
Frame = -1
Query: 181 LAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQVFDAKNMMAACDPRHGRYLT 240
+AVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQ+FDAKNMMAACDPRHGRYLT
Sbjct: 389 VAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLT 210
Query: 241 VAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMAVTFIGNST 300
VAA+FRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKM+ TFIGNST
Sbjct: 209 VAAMFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSGTFIGNST 30
Query: 301 AIQ-ELFKR 308
AIQ LFKR
Sbjct: 29 AIQGRLFKR 3
Score = 23.1 bits (48), Expect(2) = 6e-69, Method: Compositional matrix adjust.
Identities = 9/9 (100%), Positives = 9/9 (100%)
Frame = -2
Query: 170 FPGQLNADL 178
FPGQLNADL
Sbjct: 424 FPGQLNADL 398
>31457
Length = 1530
Score = 248 bits (633), Expect = 3e-66, Method: Compositional matrix adjust.
Identities = 115/119 (96%), Positives = 118/119 (99%)
Frame = +3
Query: 237 RYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMAVTFI 296
+YLTVAA+FRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKM+ TFI
Sbjct: 234 KYLTVAAMFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSSTFI 413
Query: 297 GNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQD 355
GNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQD
Sbjct: 414 GNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQD 590
>12457
Length = 781
Score = 198 bits (503), Expect = 3e-51, Method: Compositional matrix adjust.
Identities = 93/231 (40%), Positives = 135/231 (58%)
Frame = -1
Query: 1 MDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQG 60
+D VR+G + Q+F P+ V G+ A NN+A+GHYT G E+VD VLD +RK A+ C LQG
Sbjct: 694 VDEVRTGTYRQLFHPEQLVTGKEDAANNYARGHYTIGKEIVDLVLDRIRKLADQCTGLQG 515
Query: 61 FQXXXXXXXXXXXXXXXXXXXKIREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQL 120
F ++ +Y + F++ P+P+VS VVEPYN+ L+ H
Sbjct: 514 FLIFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFAIYPAPQVSTAVVEPYNSILTTHTT 335
Query: 121 VENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRK 180
+E++D + +DNEA+YDIC R L + PTY +LN L+ +S +T LRF G LN DL +
Sbjct: 334 LEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTE 155
Query: 181 LAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQVFDAKNMMAAC 231
N+VP+PR+HF + +AP+ S + LTV E+T F+ N M C
Sbjct: 154 FQTNLVPYPRIHFPLATYAPVISAEKAYHEQLTVAEITNACFEPANQMVKC 2
>05902
Length = 1127
Score = 152 bits (384), Expect = 2e-37, Method: Compositional matrix adjust.
Identities = 90/282 (31%), Positives = 158/282 (56%), Gaps = 12/282 (4%)
Frame = +2
Query: 82 KIREEYPDRIMNTFSVVPS-PKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICF 140
K+ + +P +++ T+SV P+ ++SD VV+PYN+ L++ +L +N D +DN AL I
Sbjct: 74 KLNDRFPKKLIQTYSVFPNVDEISDVVVQPYNSLLTLKRLTQNADCVVVLDNTALNRIAA 253
Query: 141 RTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAP 200
L + TPT+ +N LVS MS TT LR+PG +N DL L +++P PRLHF M G+ P
Sbjct: 254 DRLHIDTPTFAQVNQLVSTVMSTSTTTLRYPGYMNNDLIGLIASLIPTPRLHFLMTGYTP 433
Query: 201 LTSRGS-QQYRALTVPELTQQVFDAKNMMAACDPRHGR----YLTVAAVFRGRMSMKEVD 255
LT+ R TV ++ +++ KNMM + P H + Y+++ + +G + +V
Sbjct: 434 LTTDSQVANVRKTTVLDVMRRLLQPKNMMVST-PVHRQANHCYISILNIIQGEVDPTQVH 610
Query: 256 EQMLNVQNKNSSYFVEWIPNNVKTAVCDIPP---RGLKMAVTFIGNSTAIQELFKRISEQ 312
+ + ++ + + F+ W P +++ A+ P +++ + N T+I LF+RI Q
Sbjct: 611 KSLQRIRERKLAQFIPWGPASIQVALSRKSPYVQTAHRVSGLMLANHTSISHLFERILRQ 790
Query: 313 FTAMFRRKAFLHWYTGEGM--DEM-EFTEAESNMNDLVSEYQ 351
+ + +R+AF+ + E + D + EF + + LV EYQ
Sbjct: 791 YDKLRKREAFMDQFKKEAIFKDNLDEFDNSREALQLLVDEYQ 916
>25015
Length = 458
Score = 136 bits (342), Expect = 2e-32, Method: Compositional matrix adjust.
Identities = 62/62 (100%), Positives = 62/62 (100%)
Frame = -3
Query: 1 MDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQG 60
MDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQG
Sbjct: 204 MDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQG 25
Query: 61 FQ 62
FQ
Sbjct: 24 FQ 19
>03702
Length = 1932
Score = 120 bits (302), Expect = 7e-28, Method: Compositional matrix adjust.
Identities = 59/140 (42%), Positives = 83/140 (59%), Gaps = 1/140 (0%)
Frame = +1
Query: 95 FSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLN 154
F++ P+P+VS VVEPYN+ L+ H +E++D + +DNEA+YDIC R L + P Y +LN
Sbjct: 1501 FAIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPXYTNLN 1680
Query: 155 HLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPG-FAPLTSRGSQQYRALT 213
L+ +S +T LRF G LN DL + N+VP P H PG P+ S + LT
Sbjct: 1681 RLIGQIVSSITASLRFDGALNVDLTEFQTNLVPTP--HPLPPGHLCPVISAEKAYHEQLT 1854
Query: 214 VPELTQQVFDAKNMMAACDP 233
V E+T F+ N + CDP
Sbjct: 1855 VAEVTNACFEPANQLVKCDP 1914
>39157
Length = 488
Score = 80.5 bits (197), Expect(2) = 7e-20, Method: Compositional matrix adjust.
Identities = 43/55 (78%), Positives = 46/55 (83%), Gaps = 3/55 (5%)
Frame = -1
Query: 1 MDSVRSG-PFG-QIFRPDNFVFGQSGAGNNWAKGHYTE-GAELVDSVLDVVRKEA 52
MDSVRSG PFG +IFRPDNFVFGQSGAGNNW + T+ GAELVDSVLDVVRK
Sbjct: 227 MDSVRSGSPFGPKIFRPDNFVFGQSGAGNNWGQKDTTQRGAELVDSVLDVVRKRG 63
Score = 34.3 bits (77), Expect(2) = 7e-20, Method: Compositional matrix adjust.
Identities = 13/13 (100%), Positives = 13/13 (100%)
Frame = -2
Query: 50 KEAESCDCLQGFQ 62
KEAESCDCLQGFQ
Sbjct: 70 KEAESCDCLQGFQ 32
>17215
Length = 632
Score = 84.0 bits (206), Expect = 9e-17, Method: Compositional matrix adjust.
Identities = 38/117 (32%), Positives = 67/117 (57%), Gaps = 8/117 (6%)
Frame = +3
Query: 244 VFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPP--------RGLKMAVTF 295
++RG + K+V+ + ++ K + FV+W P K + PP ++ AV
Sbjct: 6 LYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCM 185
Query: 296 IGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQ 352
+ N+TAI E + R+ +F M+ ++AF+HWY GEGM+E EF+EA ++ L +Y++
Sbjct: 186 LSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEE 356
>06360
Length = 1896
Score = 79.7 bits (195), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 39/105 (37%), Positives = 58/105 (55%)
Frame = -1
Query: 1 MDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQG 60
+D VR+G + Q+F P+ V G+ A NN+A+GHYT G E+VD VLD +RK A+ C LQG
Sbjct: 1488 VDEVRTGTYRQLFHPEQLVTGKEDAANNYARGHYTIGKEIVDLVLDRIRKLADQCTGLQG 1309
Query: 61 FQXXXXXXXXXXXXXXXXXXXKIREEYPDRIMNTFSVVPSPKVSD 105
F ++ +Y + F++ P+P+VSD
Sbjct: 1308 FLIFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFAIYPAPQVSD 1174
>29025
Length = 395
Score = 35.8 bits (81), Expect = 0.031, Method: Compositional matrix adjust.
Identities = 16/16 (100%), Positives = 16/16 (100%)
Frame = -3
Query: 340 ESNMNDLVSEYQQYQD 355
ESNMNDLVSEYQQYQD
Sbjct: 354 ESNMNDLVSEYQQYQD 307
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000383307 | hsapiens_gene_ensembl | Tubulin beta
chain (Tubulin beta-5 chain). [Source:Uniprot/SWISSPROT;Acc:P07437]
(426 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
13181 459 e-130
04882 436 e-123
16482 429 e-120
00276 277 7e-75
28905 256 4e-69
31457 247 5e-66
25015 242 2e-64
12457 209 1e-54
39157 188 7e-52
05902 152 3e-37
03702 120 8e-28
06360 120 9e-28
17215 84 1e-16
29025 36 0.037
>13181
Length = 1092
Score = 459 bits (1182), Expect = e-130, Method: Compositional matrix adjust.
Identities = 215/220 (97%), Positives = 219/220 (99%)
Frame = -3
Query: 190 YDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFM 249
YDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFM
Sbjct: 1090 YDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFM 911
Query: 250 PGFAPLTSRGSQQYRALTVPELTQQVFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVD 309
PGFAPLTSRGSQQYRALTVPELTQQ+FDAKNMMAACDPRHGRYLTVAA+FRGRMSMKEVD
Sbjct: 910 PGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAMFRGRMSMKEVD 731
Query: 310 EQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMAVTFIGNSTAIQELFKRISEQFTA 369
EQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKM+ TF+GNSTAIQELFKRISEQFTA
Sbjct: 730 EQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFVGNSTAIQELFKRISEQFTA 551
Query: 370 MFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQD 409
MFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQD
Sbjct: 550 MFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQD 431
>04882
Length = 1136
Score = 436 bits (1122), Expect = e-123, Method: Compositional matrix adjust.
Identities = 204/209 (97%), Positives = 208/209 (99%)
Frame = +2
Query: 201 TPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGS 260
TPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGS
Sbjct: 320 TPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGS 499
Query: 261 QQYRALTVPELTQQVFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNS 320
QQYRALTVPELTQQ+FD+KNMMAACDPRHGRYLTVAA+FRGRMSMKEVDEQMLNVQNKNS
Sbjct: 500 QQYRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNS 679
Query: 321 SYFVEWIPNNVKTAVCDIPPRGLKMAVTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWY 380
SYFVEWIPNNVKTAVCDIPPRGLKM+ TFIGNSTAIQELFKRISEQFTAMFRRKAFLHWY
Sbjct: 680 SYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWY 859
Query: 381 TGEGMDEMEFTEAESNMNDLVSEYQQYQD 409
TGEGMDEMEFTEAESNMNDLVSEYQQYQD
Sbjct: 860 TGEGMDEMEFTEAESNMNDLVSEYQQYQD 946
>16482
Length = 837
Score = 429 bits (1103), Expect = e-120, Method: Compositional matrix adjust.
Identities = 205/227 (90%), Positives = 208/227 (91%)
Frame = +1
Query: 2 FWEVISDEHGIDPTGTYHGDSDLQLDRISVYYNEATGGKYVPRAILVDLEPGTMDSVRSG 61
FWEVISDEHGIDPTGTYHGDSDLQL+RI+VYYNEATGGKYVPRA+LVDLEPGTMDSVRSG
Sbjct: 157 FWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGKYVPRAVLVDLEPGTMDSVRSG 336
Query: 62 PFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQXXXXX 121
PFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQ
Sbjct: 337 PFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQLTHSL 516
Query: 122 XXXXXXXXXXXXXXKIREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVENTDET 181
KIREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVENTDET
Sbjct: 517 GGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVENTDET 696
Query: 182 YCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQL 228
YCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQL
Sbjct: 697 YCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQL 837
>00276
Length = 1330
Score = 277 bits (708), Expect = 7e-75, Method: Compositional matrix adjust.
Identities = 133/355 (37%), Positives = 204/355 (57%), Gaps = 8/355 (2%)
Frame = -3
Query: 60 SGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQXXX 119
+G + Q+ P+ V G+ A NN+A+GHYT G ELVD VLD +RK A+ C LQGF
Sbjct: 1328 TGTYRQL-SPEQLVTGKEDAANNYARGHYTIGKELVDLVLDRIRKLADQCTGLQGFLIFH 1152
Query: 120 XXXXXXXXXXXXXXXXKIREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVENTD 179
++ +Y + F + P+P+VS VVEPYN+ L+ H +E++D
Sbjct: 1151 SFGGGTGSGFTSLXMERLSVDYGKKSKLEFXIYPAPQVSTAVVEPYNSILTTHTTLEHSD 972
Query: 180 ETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNM 239
+ +DNEA+YDIC R L + PTY +LN L+ +S +T LRF G LN DL + N+
Sbjct: 971 CAFMVDNEAIYDICRRNLDIERPTYTNLNRLIXQIVSSITASLRFDGALNVDLTEFQTNL 792
Query: 240 VPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQVFDAKNMMAACDPRHGRYLTVAAVF 299
VP+PR+HF + +AP+ S + L V E+T F+ N + CDPRHG+Y+ ++
Sbjct: 791 VPYPRIHFPLATYAPVISAEKAYHEQLXVAEITNACFEPANQLVKCDPRHGKYMACCMLY 612
Query: 300 RGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPP--------RGLKMAVTFIG 351
RG + K+V+ + ++ K + FV+W P K + PP ++ AV +
Sbjct: 611 RGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLS 432
Query: 352 NSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQ 406
N+TAI E + R+ +F M+ ++AF+HWY GEGM+E EF+EA ++ L +Y++
Sbjct: 431 NTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEE 267
>28905
Length = 425
Score = 256 bits (654), Expect(2) = 4e-69, Method: Compositional matrix adjust.
Identities = 122/129 (94%), Positives = 126/129 (97%), Gaps = 1/129 (0%)
Frame = -1
Query: 235 LAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQVFDAKNMMAACDPRHGRYLT 294
+AVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQ+FDAKNMMAACDPRHGRYLT
Sbjct: 389 VAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLT 210
Query: 295 VAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMAVTFIGNST 354
VAA+FRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKM+ TFIGNST
Sbjct: 209 VAAMFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSGTFIGNST 30
Query: 355 AIQ-ELFKR 362
AIQ LFKR
Sbjct: 29 AIQGRLFKR 3
Score = 23.9 bits (50), Expect(2) = 4e-69, Method: Composition-based stats.
Identities = 9/9 (100%), Positives = 9/9 (100%)
Frame = -2
Query: 224 FPGQLNADL 232
FPGQLNADL
Sbjct: 424 FPGQLNADL 398
>31457
Length = 1530
Score = 247 bits (631), Expect = 5e-66, Method: Compositional matrix adjust.
Identities = 115/119 (96%), Positives = 118/119 (99%)
Frame = +3
Query: 291 RYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMAVTFI 350
+YLTVAA+FRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKM+ TFI
Sbjct: 234 KYLTVAAMFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSSTFI 413
Query: 351 GNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQD 409
GNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQD
Sbjct: 414 GNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQD 590
>25015
Length = 458
Score = 242 bits (618), Expect = 2e-64, Method: Compositional matrix adjust.
Identities = 112/115 (97%), Positives = 115/115 (100%)
Frame = -3
Query: 2 FWEVISDEHGIDPTGTYHGDSDLQLDRISVYYNEATGGKYVPRAILVDLEPGTMDSVRSG 61
FWEVISDEHGIDPTGTYHGDSDLQL+RI+VYYNEATGGKYVPRA+LVDLEPGTMDSVRSG
Sbjct: 363 FWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGKYVPRAVLVDLEPGTMDSVRSG 184
Query: 62 PFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQ 116
PFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQ
Sbjct: 183 PFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQ 19
>12457
Length = 781
Score = 209 bits (533), Expect = 1e-54, Method: Compositional matrix adjust.
Identities = 99/239 (41%), Positives = 141/239 (58%)
Frame = -1
Query: 47 LVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEA 106
LVDLEP +D VR+G + Q+F P+ V G+ A NN+A+GHYT G E+VD VLD +RK A
Sbjct: 718 LVDLEPTVVDEVRTGTYRQLFHPEQLVTGKEDAANNYARGHYTIGKEIVDLVLDRIRKLA 539
Query: 107 ESCDCLQGFQXXXXXXXXXXXXXXXXXXXKIREEYPDRIMNTFSVVPSPKVSDTVVEPYN 166
+ C LQGF ++ +Y + F++ P+P+VS VVEPYN
Sbjct: 538 DQCTGLQGFLIFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFAIYPAPQVSTAVVEPYN 359
Query: 167 ATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPG 226
+ L+ H +E++D + +DNEA+YDIC R L + PTY +LN L+ +S +T LRF G
Sbjct: 358 SILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDG 179
Query: 227 QLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQVFDAKNMMAAC 285
LN DL + N+VP+PR+HF + +AP+ S + LTV E+T F+ N M C
Sbjct: 178 ALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLTVAEITNACFEPANQMVKC 2
>39157
Length = 488
Score = 188 bits (477), Expect(2) = 7e-52, Method: Compositional matrix adjust.
Identities = 93/108 (86%), Positives = 99/108 (91%), Gaps = 3/108 (2%)
Frame = -1
Query: 2 FWEVISDEHGIDPTGTYHGDSDLQLDRISVYYNEATGGKYVPRAILVDLEPGTMDSVRSG 61
FWEVISDEHGIDPTGTYHGDSDLQL+RI+VYYNEATGGKYVPRA+LVDLEPGTMDSVRSG
Sbjct: 386 FWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGKYVPRAVLVDLEPGTMDSVRSG 207
Query: 62 -PFG-QIFRPDNFVFGQSGAGNNWAKGHYTE-GAELVDSVLDVVRKEA 106
PFG +IFRPDNFVFGQSGAGNNW + T+ GAELVDSVLDVVRK
Sbjct: 206 SPFGPKIFRPDNFVFGQSGAGNNWGQKDTTQRGAELVDSVLDVVRKRG 63
Score = 34.3 bits (77), Expect(2) = 7e-52, Method: Compositional matrix adjust.
Identities = 13/13 (100%), Positives = 13/13 (100%)
Frame = -2
Query: 104 KEAESCDCLQGFQ 116
KEAESCDCLQGFQ
Sbjct: 70 KEAESCDCLQGFQ 32
>05902
Length = 1127
Score = 152 bits (383), Expect = 3e-37, Method: Compositional matrix adjust.
Identities = 90/282 (31%), Positives = 158/282 (56%), Gaps = 12/282 (4%)
Frame = +2
Query: 136 KIREEYPDRIMNTFSVVPS-PKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICF 194
K+ + +P +++ T+SV P+ ++SD VV+PYN+ L++ +L +N D +DN AL I
Sbjct: 74 KLNDRFPKKLIQTYSVFPNVDEISDVVVQPYNSLLTLKRLTQNADCVVVLDNTALNRIAA 253
Query: 195 RTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAP 254
L + TPT+ +N LVS MS TT LR+PG +N DL L +++P PRLHF M G+ P
Sbjct: 254 DRLHIDTPTFAQVNQLVSTVMSTSTTTLRYPGYMNNDLIGLIASLIPTPRLHFLMTGYTP 433
Query: 255 LTSRGS-QQYRALTVPELTQQVFDAKNMMAACDPRHGR----YLTVAAVFRGRMSMKEVD 309
LT+ R TV ++ +++ KNMM + P H + Y+++ + +G + +V
Sbjct: 434 LTTDSQVANVRKTTVLDVMRRLLQPKNMMVST-PVHRQANHCYISILNIIQGEVDPTQVH 610
Query: 310 EQMLNVQNKNSSYFVEWIPNNVKTAVCDIPP---RGLKMAVTFIGNSTAIQELFKRISEQ 366
+ + ++ + + F+ W P +++ A+ P +++ + N T+I LF+RI Q
Sbjct: 611 KSLQRIRERKLAQFIPWGPASIQVALSRKSPYVQTAHRVSGLMLANHTSISHLFERILRQ 790
Query: 367 FTAMFRRKAFLHWYTGEGM--DEM-EFTEAESNMNDLVSEYQ 405
+ + +R+AF+ + E + D + EF + + LV EYQ
Sbjct: 791 YDKLRKREAFMDQFKKEAIFKDNLDEFDNSREALQLLVDEYQ 916
>03702
Length = 1932
Score = 120 bits (302), Expect = 8e-28, Method: Compositional matrix adjust.
Identities = 59/140 (42%), Positives = 83/140 (59%), Gaps = 1/140 (0%)
Frame = +1
Query: 149 FSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLN 208
F++ P+P+VS VVEPYN+ L+ H +E++D + +DNEA+YDIC R L + P Y +LN
Sbjct: 1501 FAIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPXYTNLN 1680
Query: 209 HLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPG-FAPLTSRGSQQYRALT 267
L+ +S +T LRF G LN DL + N+VP P H PG P+ S + LT
Sbjct: 1681 RLIGQIVSSITASLRFDGALNVDLTEFQTNLVPTP--HPLPPGHLCPVISAEKAYHEQLT 1854
Query: 268 VPELTQQVFDAKNMMAACDP 287
V E+T F+ N + CDP
Sbjct: 1855 VAEVTNACFEPANQLVKCDP 1914
>06360
Length = 1896
Score = 120 bits (302), Expect = 9e-28, Method: Compositional matrix adjust.
Identities = 61/159 (38%), Positives = 88/159 (55%), Gaps = 2/159 (1%)
Frame = -1
Query: 3 WEVISDEHGIDPTGTYHGDSDLQL--DRISVYYNEATGGKYVPRAILVDLEPGTMDSVRS 60
WE+ EHGI P G D + D + +++E GK+VPRA+ VDLEP +D VR+
Sbjct: 1650 WELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVVDEVRT 1471
Query: 61 GPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQXXXX 120
G + Q+F P+ V G+ A NN+A+GHYT G E+VD VLD +RK A+ C LQGF
Sbjct: 1470 GTYRQLFHPEQLVTGKEDAANNYARGHYTIGKEIVDLVLDRIRKLADQCTGLQGFLIFHS 1291
Query: 121 XXXXXXXXXXXXXXXKIREEYPDRIMNTFSVVPSPKVSD 159
++ +Y + F++ P+P+VSD
Sbjct: 1290 FGGGTGSGFTSLLMERLSVDYGKKSKLEFAIYPAPQVSD 1174
>17215
Length = 632
Score = 84.0 bits (206), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 38/117 (32%), Positives = 67/117 (57%), Gaps = 8/117 (6%)
Frame = +3
Query: 298 VFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPP--------RGLKMAVTF 349
++RG + K+V+ + ++ K + FV+W P K + PP ++ AV
Sbjct: 6 LYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCM 185
Query: 350 IGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQ 406
+ N+TAI E + R+ +F M+ ++AF+HWY GEGM+E EF+EA ++ L +Y++
Sbjct: 186 LSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEE 356
>29025
Length = 395
Score = 35.8 bits (81), Expect = 0.037, Method: Compositional matrix adjust.
Identities = 16/16 (100%), Positives = 16/16 (100%)
Frame = -3
Query: 394 ESNMNDLVSEYQQYQD 409
ESNMNDLVSEYQQYQD
Sbjct: 354 ESNMNDLVSEYQQYQD 307
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000358921 | hsapiens_gene_ensembl |
Alpha-centractin (Centractin) (Centrosome-associated actin homolog)
(Actin-RPV) (ARP1). [Source:Uniprot/SWISSPROT;Acc:P61163]
(376 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
04742 436 e-123
12322 372 e-103
39562 355 2e-98
02757 141 2e-63
00608 181 6e-46
32273 180 1e-45
01436 131 4e-31
19721 92 4e-30
36954 117 5e-27
18926 94 1e-19
11487 66 4e-19
13361 87 1e-17
26639 31 0.66
00310 28 4.3
04121 28 4.7
14855 28 6.8
>04742
Length = 2111
Score = 436 bits (1120), Expect = e-123, Method: Compositional matrix adjust.
Identities = 198/369 (53%), Positives = 275/369 (74%), Gaps = 4/369 (1%)
Frame = +2
Query: 12 VVIDNGSGVIKAGFAGDQIPKYCFPNYVGRPKHVRVMAGALEGDIFIGPKAEEHRGLLSI 71
+VIDNGSG+ KAGFAGD P+ FP+ VGRP+H VM G + D ++G +A+ RG+L++
Sbjct: 116 LVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTL 295
Query: 72 RYPMEHGIVKDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPRKNRERAAEVFFET 131
+YP+EHGIV +W+DME+IW + + ++L+ EEHPVLLTEAPLNP+ NRE+ ++ FET
Sbjct: 296 KYPIEHGIVTNWDDMEKIWHHTF-YNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFET 472
Query: 132 FNVPALFISMQAVLSLYATGRTTGVVLDSGDGVTHAVPIYEGFAMPHSIMRIDIAGRDVS 191
FN PA+++++QAVLSLYA+GRTTG+VLDSGDGV H VPIYEG+A+PH+I R+D+AGRD++
Sbjct: 473 FNSPAMYVAIQAVLSLYASGRTTGIVLDSGDGVXHTVPIYEGYALPHAISRLDLAGRDLT 652
Query: 192 RFLRLYLRKEGYDFHSSSEFEIVKAIKERACYLSIN-PQKDETLETEKA---QYYLPDGS 247
+L L + GY F +++E EIV+ IKE+ CY++++ Q+ +T + + Y LPDG
Sbjct: 653 DYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMQTAASSSSLEKSYELPDGQ 832
Query: 248 TIEIGPSRFRAPELLFRPDLIGEESEGIHEVLVFAIQKSDMDLRRTLFSNIVLSGGSTLF 307
I IG RFR PE +F+P +G ES G HE +I K D+D+R+ L++N VLSGGST++
Sbjct: 833 VITIGNERFRCPEAMFQPSFLGMESAGXHETTYNSIMKCDVDIRKDLYANTVLSGGSTMY 1012
Query: 308 KGFGDRLLSEVKKLAPKDVKIRISAPQERLYSTWIGGSILASLDTFKKMWVSKKEYEEDG 367
G DR+ E+ LAP +KI+I AP ER YS WIGGSILASL TF++MW+SK+EY+E G
Sbjct: 1013PGIADRMQKEITALAPPTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESG 1192
Query: 368 ARSIHRKTF 376
+HRK F
Sbjct: 1193PSIVHRKCF 1219
>12322
Length = 849
Score = 372 bits (955), Expect = e-103, Method: Compositional matrix adjust.
Identities = 170/213 (79%), Positives = 199/213 (93%)
Frame = +1
Query: 164 VTHAVPIYEGFAMPHSIMRIDIAGRDVSRFLRLYLRKEGYDFHSSSEFEIVKAIKERACY 223
VTHAVP+YEGFAMPHSIMR+D+AGRDV+R+LRL LRKEG D H+++EFE+VK IKER CY
Sbjct: 1 VTHAVPVYEGFAMPHSIMRVDVAGRDVTRYLRLLLRKEGMDLHTTAEFEVVKHIKERTCY 180
Query: 224 LSINPQKDETLETEKAQYYLPDGSTIEIGPSRFRAPELLFRPDLIGEESEGIHEVLVFAI 283
LSINP K+E+++TEK Y LPDG+T+E+GP+RFRAPELLFRPDLIGEE EGIHEVL ++I
Sbjct: 181 LSINPLKEESVDTEKVSYTLPDGNTVEVGPARFRAPELLFRPDLIGEECEGIHEVLSYSI 360
Query: 284 QKSDMDLRRTLFSNIVLSGGSTLFKGFGDRLLSEVKKLAPKDVKIRISAPQERLYSTWIG 343
QKSD+DLR+TL+SNIVLSGGSTLFKGFGDRLLSE+KKLAPKD+KIRISAPQERLYSTWIG
Sbjct: 361 QKSDVDLRKTLYSNIVLSGGSTLFKGFGDRLLSELKKLAPKDIKIRISAPQERLYSTWIG 540
Query: 344 GSILASLDTFKKMWVSKKEYEEDGARSIHRKTF 376
SILASLDTF+KMWVSK+EY E+G ++IHRKTF
Sbjct: 541 XSILASLDTFRKMWVSKREYHEEGVKAIHRKTF 639
>39562
Length = 1438
Score = 355 bits (911), Expect = 2e-98, Method: Compositional matrix adjust.
Identities = 162/302 (53%), Positives = 226/302 (74%), Gaps = 4/302 (1%)
Frame = -2
Query: 79 IVKDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPRKNRERAAEVFFETFNVPALF 138
IV +W+DME+IW + + ++L+ EEHPVLLTEAPLNP+ NRE+ ++ FETFN PA++
Sbjct: 1437 IVTNWDDMEKIWHHTF-YNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNSPAMY 1261
Query: 139 ISMQAVLSLYATGRTTGVVLDSGDGVTHAVPIYEGFAMPHSIMRIDIAGRDVSRFLRLYL 198
+++QAVLSLYA+GRTTG+VLDSGDGVTH VPIYEG+A+PH+IMR+D+AGRD++ +L L
Sbjct: 1260 VAIQAVLSLYASGRTTGIVLDSGDGVTHTVPIYEGYALPHAIMRLDLAGRDLTDYLMKIL 1081
Query: 199 RKEGYDFHSSSEFEIVKAIKERACYLSINPQKD----ETLETEKAQYYLPDGSTIEIGPS 254
+ GY F +++E EIV+ IKE+ Y++++ +++ + + + Y LPDG I IG
Sbjct: 1080 TERGYSFTTTAEREIVRDIKEKLDYVALDFEQEMLTAASSSSLEKSYELPDGQVITIGNE 901
Query: 255 RFRAPELLFRPDLIGEESEGIHEVLVFAIQKSDMDLRRTLFSNIVLSGGSTLFKGFGDRL 314
RFR PE +F+P +G ES GIHE +I K D+D+R+ L++N VLSGGST++ G DR+
Sbjct: 900 RFRCPEAMFQPSFLGMESAGIHETTYNSIMKCDVDIRKDLYANTVLSGGSTMYPGIADRM 721
Query: 315 LSEVKKLAPKDVKIRISAPQERLYSTWIGGSILASLDTFKKMWVSKKEYEEDGARSIHRK 374
E+ LAP +KI+I AP ER YS WIGGSILASL TF++MW+SK+EY+E G +HRK
Sbjct: 720 QKEITALAPPTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRK 541
Query: 375 TF 376
F
Sbjct: 540 CF 535
>02757
Length = 1094
Score = 141 bits (355), Expect(3) = 2e-63, Method: Compositional matrix adjust.
Identities = 66/152 (43%), Positives = 99/152 (65%), Gaps = 4/152 (2%)
Frame = -2
Query: 177 PHSIMRIDIAGRDVSRFLRLYLRKEGYDFHSSSEFEIVKAIKERACYLSINPQKDETLET 236
P +I+R+D+AGRD++ +L L + GY F +++E EIV IKE+ CY++++ +++
Sbjct: 997 PTAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVXDIKEKLCYVALDFEQEMATAA 818
Query: 237 EKAQ----YYLPDGSTIEIGPSRFRAPELLFRPDLIGEESEGIHEVLVFAIQKSDMDLRR 292
+ Y LPDG I IG RFR PE LF+P +G ES GIHE +I K D+D+R+
Sbjct: 817 SSSSLEKSYELPDGQVITIGNERFRCPESLFQPSFLGMESAGIHETTYNSIMKCDVDIRK 638
Query: 293 TLFSNIVLSGGSTLFKGFGDRLLSEVKKLAPK 324
L++N VLSGG+T+F G DR+ E+ LAP+
Sbjct: 637 DLYANTVLSGGTTMFPGIADRMQKEITALAPQ 542
Score = 73.6 bits (179), Expect(3) = 2e-63, Method: Compositional matrix adjust.
Identities = 32/51 (62%), Positives = 40/51 (78%)
Frame = -3
Query: 326 VKIRISAPQERLYSTWIGGSILASLDTFKKMWVSKKEYEEDGARSIHRKTF 376
+KI+ AP ER YS WIGGSILASL TF++MW+SK+EY+E G +HRK F
Sbjct: 537 MKIKXIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF 385
Score = 67.0 bits (162), Expect(3) = 2e-63, Method: Compositional matrix adjust.
Identities = 29/34 (85%), Positives = 33/34 (97%)
Frame = -1
Query: 145 LSLYATGRTTGVVLDSGDGVTHAVPIYEGFAMPH 178
LSLYA+GRTTG+VLDSGDGVTH VPIYEG+A+PH
Sbjct: 1094 LSLYASGRTTGIVLDSGDGVTHTVPIYEGYALPH 993
>00608
Length = 1930
Score = 181 bits (458), Expect = 6e-46, Method: Compositional matrix adjust.
Identities = 116/324 (35%), Positives = 182/324 (56%), Gaps = 35/324 (10%)
Frame = +3
Query: 79 IVKDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPRKNRERAAEVFFETFNVPALF 138
I+ DW+ MER ++ V K L+ E+H LLTE PLN +NRE AE+ FE+FNVP L+
Sbjct: 3 IIDDWDLMERFYEQVIFK-YLRAEPEDHYFLLTEPPLNTPENREYTAEIMFESFNVPGLY 179
Query: 139 ISMQAVLSLYATGRT--------TGVVLDSGDGVTHAVPIYEGFAMPHSIMRIDIAGRDV 190
I++QAVL+L A+ + TG V+DSGDGVTH +P+ EG+ + I I IAGRD+
Sbjct: 180 IAVQAVLALAASWTSRNVGERTLTGTVIDSGDGVTHVIPVAEGYVIGSCIKHIPIAGRDI 359
Query: 191 SRFLRLYLRKEGYDFHSSSEFEIVKAIKERACYLSINPQKD----ETLETEKAQYYLPDG 246
+ F++ LR+ E KAIKER Y+ + K+ +T ++ + Y
Sbjct: 360 TYFIQQLLREREVGIPPEQSLETAKAIKERFSYVCPDIAKEFSKYDTDPSKWMKKYEGRN 539
Query: 247 S------TIEIGPSRFRAPELLFRPDLIGEE-SEGIHEVLVFAIQKSDMDLRRTLFSNIV 299
+ ++++G RF PE+ F P+ + + I +V+ IQ +D+RR L+ NIV
Sbjct: 540 TISKQLFSVDVGYERFLGPEIFFHPEFSNPDFTMPISDVVDDVIQNCPIDVRRGLYKNIV 719
Query: 300 LSGGSTLFKGFGDRLLSEVK----------------KLAPKDVKIRISAPQERLYSTWIG 343
LSGGST+F+ FG ++ +VK ++ PK +++++ + Y+ W G
Sbjct: 720 LSGGSTMFRDFGRKIQRDVKRVVDGRLKASEELSQGRIKPKPIEVQVITHHMQRYAVWFG 899
Query: 344 GSILASLDTFKKMWVSKKEYEEDG 367
GS+LAS F ++ +K +Y+E G
Sbjct: 900 GSMLASTPEFYQVCHTKADYDEHG 971
>32273
Length = 265
Score = 180 bits (456), Expect = 1e-45, Method: Compositional matrix adjust.
Identities = 81/88 (92%), Positives = 87/88 (98%)
Frame = -2
Query: 68 LLSIRYPMEHGIVKDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPRKNRERAAEV 127
L+SIRYPMEHGIVKDWNDMERIWQY+YSKDQLQTFSEEHPVLLTEAPLNPR+NRE+AAE+
Sbjct: 264 LMSIRYPMEHGIVKDWNDMERIWQYIYSKDQLQTFSEEHPVLLTEAPLNPRRNREKAAEI 85
Query: 128 FFETFNVPALFISMQAVLSLYATGRTTG 155
FF+TFNVPALFISMQAVLSLYATGR TG
Sbjct: 84 FFDTFNVPALFISMQAVLSLYATGRITG 1
>01436
Length = 2563
Score = 131 bits (330), Expect = 4e-31, Method: Compositional matrix adjust.
Identities = 74/200 (37%), Positives = 114/200 (57%), Gaps = 16/200 (8%)
Frame = +3
Query: 190 VSRFLRLYLRKEGYDFHSSSEFEIVKAIKERACYLSINPQKDETLETEKA----QYYLPD 245
++R+L L GY F+ S++FE V+ +KE+ CY + + ++++ L E Y LPD
Sbjct: 3 ITRYLIKLLLLRGYAFNHSADFETVRMLKEKLCYTAYDVEQEQKLALETTVLVEPYILPD 182
Query: 246 GSTIEIGPSRFRAPELLFRPDLIGEESEGIHEVLVFAIQKSDMDLRRTLFSNIVLSGGST 305
G I++G RF APE LF+P LI + G+ E+L IQ +DMD+R + +IVLSGGST
Sbjct: 183 GRVIKVGGERFEAPEALFQPHLINVDGVGVAELLFNTIQAADMDIRPDFYKHIVLSGGST 362
Query: 306 LFKGFGDRLLSEVKKLAPKDV-----------KIRISAPQERLYSTWIGGSILASLDTFK 354
++ G RL E+K+L + V KIRI P R + ++GGS+ A + K
Sbjct: 363 MYPGLPSRLEREIKQLYLERVLXGDTSRLSKFKIRIEDPPRRKHMVFLGGSVXADIMKDK 542
Query: 355 -KMWVSKKEYEEDGARSIHR 373
W+ + EYEE G + + +
Sbjct: 543 DDFWMMRSEYEEMGVKVLDK 602
>19721
Length = 757
Score = 91.7 bits (226), Expect(2) = 4e-30, Method: Compositional matrix adjust.
Identities = 55/121 (45%), Positives = 79/121 (65%), Gaps = 8/121 (6%)
Frame = +2
Query: 79 IVKDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPRKNRERAAEVFFETFNVPALF 138
+V+DW+ ER + K L+ E+H LLTE PLN +NRE AE+ FETFN+P L+
Sbjct: 2 VVEDWDLHERFMEQAIFK-YLRAEPEDHYFLLTEPPLNTPENREFTAEIMFETFNIPGLY 178
Query: 139 ISMQAVLSLYATGRT--------TGVVLDSGDGVTHAVPIYEGFAMPHSIMRIDIAGRDV 190
I++QAVL+L A+ + TG V+DSGDGVTH +P+ +G+ + +I I IAGRD+
Sbjct: 179 IAVQAVLALAASWTSRPPNERTLTGTVIDSGDGVTHVIPVVDGYVIGSAIKHIPIAGRDI 358
Query: 191 S 191
+
Sbjct: 359 T 361
Score = 57.8 bits (138), Expect(2) = 4e-30, Method: Compositional matrix adjust.
Identities = 38/109 (34%), Positives = 55/109 (50%), Gaps = 12/109 (11%)
Frame = +3
Query: 212 EIVKAIKERACYLS-----------INPQKDETLETEKAQYYLPDGSTIEIGPSRFRAPE 260
E K IKER Y+ +P+K PD S ++G +F PE
Sbjct: 420 EAAKQIKERYSYVCPDIAKEFAKYDSDPEKWIKAHKMSGSSKYPDFS-FDVGYEKFLGPE 596
Query: 261 LLFRPDLI-GEESEGIHEVLVFAIQKSDMDLRRTLFSNIVLSGGSTLFK 308
+ FRP+ + G+ I +V+ IQ +D RR L++NIVLSGGS++FK
Sbjct: 597 VFFRPEFVNGDFQASISDVVDTVIQSCPIDSRRPLYNNIVLSGGSSMFK 743
>36954
Length = 892
Score = 117 bits (294), Expect = 5e-27, Method: Compositional matrix adjust.
Identities = 65/203 (32%), Positives = 111/203 (54%), Gaps = 13/203 (6%)
Frame = -1
Query: 12 VVIDNGSGVIKAGFAGDQIPKYCFPNYVGRPKHVRVMAGALEGDIFIGPKAEEHRGLLSI 71
+V D GS +AG+AG+ PK P +VG + + GD P E + L+
Sbjct: 802 LVFDIGSYSFRAGYAGEDTPKAEIPTHVGVMEDIETTMDTDGGD---APPQPEKKYLIDT 632
Query: 72 RYPMEH-------------GIVKDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPR 118
Y M+H G+V+DW+ E++ Y Y++ +++ S HP+L++E N +
Sbjct: 631 VY-MKHPRKGMHLNSFLKDGMVEDWDMFEKVIDYAYNR-SIKSESCLHPLLMSEPAWNTK 458
Query: 119 KNRERAAEVFFETFNVPALFISMQAVLSLYATGRTTGVVLDSGDGVTHAVPIYEGFAMPH 178
RE+ E+ FE +N+PA F+ +VLS +A GR+T ++LDSG T AVP+Y+G+ +
Sbjct: 457 AKREKLTEIMFEKYNIPAFFLRKNSVLSAFANGRSTALILDSGATHTSAVPVYDGYVLTQ 278
Query: 179 SIMRIDIAGRDVSRFLRLYLRKE 201
I++ +AG ++R L + ++
Sbjct: 277 GIVKSPLAGDFIARECGLLMEEQ 209
>18926
Length = 478
Score = 93.6 bits (231), Expect = 1e-19, Method: Compositional matrix adjust.
Identities = 41/105 (39%), Positives = 70/105 (66%), Gaps = 3/105 (2%)
Frame = +1
Query: 274 GIHEVLVFAIQKSDMDLRRTLFSNIVLSGGSTLFKGFGDRLLSEVKKLAPKDVKIRI--- 330
G+ V+ ++ D+D+R +L+ ++ GG++L +GF +RL ++ P ++++I
Sbjct: 97 GVGHVVTTSVGMCDIDIRPSLYGGVIAVGGNSLIQGFTERLNRDLSNKTPPSMRLKIIAA 276
Query: 331 SAPQERLYSTWIGGSILASLDTFKKMWVSKKEYEEDGARSIHRKT 375
++ ER +S+WIGGSILASL +F++MWVSK+EYEE G + RK
Sbjct: 277 ASTAERRFSSWIGGSILASLGSFQQMWVSKQEYEEGGKSCVERKC 411
>11487
Length = 771
Score = 66.2 bits (160), Expect(2) = 4e-19, Method: Compositional matrix adjust.
Identities = 28/42 (66%), Positives = 34/42 (80%)
Frame = -2
Query: 335 ERLYSTWIGGSILASLDTFKKMWVSKKEYEEDGARSIHRKTF 376
ER YS WIGGSILASL TF++MW+SK+EY+E G +HRK F
Sbjct: 599 ERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF 474
Score = 45.8 bits (107), Expect(2) = 4e-19, Method: Compositional matrix adjust.
Identities = 18/36 (50%), Positives = 27/36 (75%)
Frame = -1
Query: 282 AIQKSDMDLRRTLFSNIVLSGGSTLFKGFGDRLLSE 317
+I K D+D+R+ L++N VLSGG+T+F G DR+ E
Sbjct: 756 SIMKCDVDIRKDLYANTVLSGGTTMFPGIADRMQKE 649
>13361
Length = 1217
Score = 86.7 bits (213), Expect = 1e-17, Method: Compositional matrix adjust.
Identities = 46/137 (33%), Positives = 75/137 (54%), Gaps = 17/137 (12%)
Frame = +3
Query: 248 TIEIGPSRFRAPELLFRPDLIGEE-SEGIHEVLVFAIQKSDMDLRRTLFSNIVLSGGSTL 306
+++G RF PE+ F P+ + + + E++ IQ +D+RR L++NIVLSGGST+
Sbjct: 150 NVDVGYERFLGPEIFFHPEFSNPDFTIPLSEIVDNVIQNCPIDVRRHLYNNIVLSGGSTM 329
Query: 307 FKGFGDRLLSEVK----------------KLAPKDVKIRISAPQERLYSTWIGGSILASL 350
FK FG RL ++K ++ PK + +++ + Y+ W GGS+LAS
Sbjct: 330 FKDFGRRLQRDIKRSVDTRLRISENLSEGRIKPKPIDVQVITHHMQRYAVWFGGSMLAST 509
Query: 351 DTFKKMWVSKKEYEEDG 367
F ++ +K YEE G
Sbjct: 510 PEFYQVCHTKAAYEEYG 560
>26639
Length = 435
Score = 31.2 bits (69), Expect = 0.66, Method: Compositional matrix adjust.
Identities = 16/37 (43%), Positives = 22/37 (59%)
Frame = +2
Query: 44 HVRVMAGALEGDIFIGPKAEEHRGLLSIRYPMEHGIV 80
H +V+AGALEGD+ G +IR P++HG V
Sbjct: 71 HGKVLAGALEGDV----------GSTNIRXPVQHGHV 151
>00310
Length = 2568
Score = 28.5 bits (62), Expect = 4.3, Method: Compositional matrix adjust.
Identities = 12/23 (52%), Positives = 15/23 (65%)
Frame = +3
Query: 250 EIGPSRFRAPELLFRPDLIGEES 272
++GP F PELL PDL G E+
Sbjct: 2208 QLGPGWFLVPELLV*PDLAGSEA 2276
>04121
Length = 1871
Score = 28.5 bits (62), Expect = 4.7, Method: Compositional matrix adjust.
Identities = 16/44 (36%), Positives = 25/44 (56%), Gaps = 1/44 (2%)
Frame = -1
Query: 257 RAPELLF-RPDLIGEESEGIHEVLVFAIQKSDMDLRRTLFSNIV 299
R P L F R LI ++ + + ++FA+ S +D+ TLF IV
Sbjct: 1673 RKPVLYFSRSPLINTTTQCVSKSVIFAVPPSTLDMECTLFVMIV 1542
>14855
Length = 1907
Score = 28.1 bits (61), Expect = 6.8, Method: Compositional matrix adjust.
Identities = 14/36 (38%), Positives = 21/36 (58%)
Frame = +1
Query: 197 YLRKEGYDFHSSSEFEIVKAIKERACYLSINPQKDE 232
+L + +FH S EFE +K I + CY S + Q +E
Sbjct: 994 FLHQAP*NFHVSKEFE*MKVINIKCCYESDSEQMEE 1101
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000265717 | hsapiens_gene_ensembl | cAMP-dependent
protein kinase type II-beta regulatory subunit.
[Source:Uniprot/SWISSPROT;Acc:P31323]
(418 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
08195 422 e-118
27710 138 4e-33
18204 100 2e-21
20517 46 2e-05
27148 30 2.4
27853 29 3.6
>08195
Length = 2165
Score = 422 bits (1084), Expect = e-118, Method: Compositional matrix adjust.
Identities = 216/422 (51%), Positives = 280/422 (66%), Gaps = 9/422 (2%)
Frame = -3
Query: 1 MSIEIPAGLTELLQGFTVEVLRHQPADLLEFALQHFTRLQQENER-------KGTARFGH 53
MS +IP GLTELLQ FTV LR +P+DL++FA +F RL+ N G RF
Sbjct: 2031 MSFDIPPGLTELLQEFTVAALRERPSDLVDFAASYFNRLRLLNGDAVDPKCFTGGVRFSQ 1852
Query: 54 EGRTWGDLGAAAGGGTPSKGVNFAEEPMQSDSXXXXXXXXXXXXXXXFNAPVIN--RFTR 111
G A GT ++ + +E M P N RF R
Sbjct: 1851 TGSHI-----LAHNGTFAQNNSDDDEAM-------------------LEPPPSNTARF-R 1747
Query: 112 RASVCAEAYNPDEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMF 171
R SV AEAYNP+ +ED E++I++PK+D QR RL + K+ILLF++LDPEQM +VLDAMF
Sbjct: 1746 RKSVSAEAYNPETDEDGGEAKIVNPKSDIQRQRLADVVKNILLFRSLDPEQMQEVLDAMF 1567
Query: 172 EKLVKDGEHVIDQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTP 231
EK V+ GEH+IDQGDDGDNFYVID GT+DIYV +G + VGNYDN G FGELALMYN P
Sbjct: 1566 EKSVQPGEHIIDQGDDGDNFYVIDSGTYDIYVDVEGQAKLVGNYDNSGFFGELALMYNMP 1387
Query: 232 RAATITATSPGALWGLDRVTFRRIIVKNNAKKRKMYESFIESLPFLKSLEFSERLKVVDV 291
RAATI A+S G +W LDR TFRRI++K +KRK YES +ES+P LKSL+ ER+ V D
Sbjct: 1386 RAATIIASSTGTIWALDRTTFRRIVLKTAFQKRKKYESLLESVPLLKSLDLYERMNVADA 1207
Query: 292 IGTKVYNDGEQIIAQGDSADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCSRGQYFG 351
+ T+ Y DG QII QGD+AD + VESG+V+I M K ++ G ++ +G YFG
Sbjct: 1206 LQTRTYEDGVQIIKQGDAADVMYFVESGQVRIAMTNKESTD-PSAGETDVTVLEKGGYFG 1030
Query: 352 ELALVTNKPRAASAHAIGTVKCLAMDVQAFERLLGPCMEIMKRNIATYEEQLVALFGTNM 411
ELAL+T++PRAASA+A GTVKC +DV AFERL+GPCM+++KRNI Y+ Q+ ++FG ++
Sbjct: 1029 ELALITHQPRAASAYAQGTVKCAVLDVHAFERLMGPCMDVLKRNIDDYDSQISSIFGKSV 850
Query: 412 DI 413
+
Sbjct: 849 SM 844
>27710
Length = 429
Score = 138 bits (348), Expect = 4e-33, Method: Compositional matrix adjust.
Identities = 68/141 (48%), Positives = 94/141 (66%)
Frame = +2
Query: 179 EHVIDQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTPRAATITA 238
E++I QGD+GDNFYVID G D++V + V GSFGELAL+Y TPRAAT+ A
Sbjct: 2 ENIIQQGDEGDNFYVIDVGEVDVFVNSE----LVTTISEGGSFGELALIYGTPRAATVRA 169
Query: 239 TSPGALWGLDRVTFRRIIVKNNAKKRKMYESFIESLPFLKSLEFSERLKVVDVIGTKVYN 298
S LWG+DR ++RRI++ + +KRKMYE F+ + L+SL+ ERL V D + T ++
Sbjct: 170 KSDVKLWGIDRDSYRRILMGSTIRKRKMYEEFLSRVSILESLDKWERLTVADSLETCAFD 349
Query: 299 DGEQIIAQGDSADSFFIVESG 319
DGE I+ QG + D F+I+ G
Sbjct: 350 DGETIVKQGAAGDDFYIILEG 412
Score = 57.0 bits (136), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 36/103 (34%), Positives = 54/103 (52%)
Frame = +2
Query: 301 EQIIAQGDSADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCSRGQYFGELALVTNKP 360
E II QGD D+F++++ GEV + + + + + E G+ FGELAL+ P
Sbjct: 2 ENIIQQGDEGDNFYVIDVGEVDVFVNSELVTTISEGGS-----------FGELALIYGTP 148
Query: 361 RAASAHAIGTVKCLAMDVQAFERLLGPCMEIMKRNIATYEEQL 403
RAA+ A VK +D ++ R+L I KR + YEE L
Sbjct: 149 RAATVRAKSDVKLWGIDRDSYRRILMGST-IRKRKM--YEEFL 268
Score = 38.9 bits (89), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 21/70 (30%), Positives = 36/70 (51%)
Frame = +2
Query: 128 DAESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKDGEHVIDQGDD 187
D+ RI+ T +R +E + + ++LD + V D++ DGE ++ QG
Sbjct: 203 DSYRRILMGSTIRKRKMYEEFLSRVSILESLDKWERLTVADSLETCAFDDGETIVKQGAA 382
Query: 188 GDNFYVIDRG 197
GD+FY+I G
Sbjct: 383 GDDFYIILEG 412
>18204
Length = 429
Score = 100 bits (248), Expect = 2e-21, Method: Compositional matrix adjust.
Identities = 53/148 (35%), Positives = 86/148 (58%)
Frame = -1
Query: 220 SFGELALMYNTPRAATITATSPGALWGLDRVTFRRIIVKNNAKKRKMYESFIESLPFLKS 279
+FGELA++YN R A++ A + +W LDR F+ I++K ++R+ F++S+ L+
Sbjct: 429 AFGELAILYNCTRTASVKAVTDVKVWVLDRQMFQAIMMKTGLQRREENIRFLKSVSVLRD 250
Query: 280 LEFSERLKVVDVIGTKVYNDGEQIIAQGDSADSFFIVESGEVKITMKRKGKSEVEENGAV 339
L + K+ DV+ +++GE II +G + D+FF++ GEV++T G E +
Sbjct: 249 LPSDKLAKIADVLEIDFFHEGEFIIREGCTGDTFFLINKGEVRVTQTVAGHEEPQ----- 85
Query: 340 EIARCSRGQYFGELALVTNKPRAASAHA 367
EI + RG YFGE AL+ R AS A
Sbjct: 84 EIRKLKRGDYFGEKALLGEDRRTASCIA 1
>20517
Length = 749
Score = 46.2 bits (108), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 46/181 (25%), Positives = 80/181 (44%), Gaps = 18/181 (9%)
Frame = +3
Query: 186 DDGDNFYVIDRGTFDI--YVKCDGVGRCVGNYDNRGSFGELALMYNTPRAATITATSPGA 243
D +FY I GT + + + R + D SFGELA++ + R AT++ +
Sbjct: 6 DPPRSFYFILSGTVVVTQFERQYSTTRTLVTLDQGMSFGELAVITGSRRQATVSTMTEVE 185
Query: 244 LWGLDRVTFRRIIVKNNAKKRKM-----YESFIESLPFLKSLEFSERLKVVDVIGTKVYN 298
L + F I + A RK+ + F+ S+ FLK+ + + +N
Sbjct: 186 LLCISAKDFEDIFM---AGGRKIITDPDHNKFLRSVDFLKAWPVQQLAQHPHACMFHYFN 356
Query: 299 DGEQIIAQGDSADSFFIVESGEVKITMK-----------RKGKSEVEENGAVEIARCSRG 347
G+ ++ +++D +IV+SG + + K +GKSEV E A + R RG
Sbjct: 357 RGQVLVRDSNNSDWIYIVKSGSLSVMKKLHHATATDRHSTEGKSEVAE--ASKSKRKKRG 530
Query: 348 Q 348
+
Sbjct: 531 R 533
>27148
Length = 718
Score = 29.6 bits (65), Expect = 2.4, Method: Compositional matrix adjust.
Identities = 14/32 (43%), Positives = 20/32 (62%)
Frame = -3
Query: 207 GVGRCVGNYDNRGSFGELALMYNTPRAATITA 238
GV + V Y+ SFGELA+M T R +T+ +
Sbjct: 314 GVAKTVMYYNRGDSFGELAIMNATRRQSTVIS 219
>27853
Length = 864
Score = 28.9 bits (63), Expect = 3.6, Method: Compositional matrix adjust.
Identities = 16/64 (25%), Positives = 30/64 (46%), Gaps = 1/64 (1%)
Frame = +2
Query: 173 KLVKDGEHVIDQGDDGDNFYVIDRGTF-DIYVKCDGVGRCVGNYDNRGSFGELALMYNTP 231
++ + G+ + QGD+ D+ Y++ G + G VG Y G + ++ +T
Sbjct: 227 QMTEAGKALFRQGDNSDSVYIVLTGRLRSVITLLGGKKEVVGEYGRGELVGIVEVLTHTE 406
Query: 232 RAAT 235
RA T
Sbjct: 407 RATT 418
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000264335 | hsapiens_gene_ensembl | 14-3-3 protein
epsilon (14-3-3E). [Source:Uniprot/SWISSPROT;Acc:P62258]
(255 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
12344 414 e-116
13465 239 1e-63
33715 175 1e-44
17028 124 3e-29
15092 108 2e-24
27988 59 6e-16
18027 28 3.2
05069 28 5.1
01750 27 6.0
>12344
Length = 1658
Score = 414 bits (1065), Expect = e-116, Method: Compositional matrix adjust.
Identities = 209/254 (82%), Positives = 225/254 (88%), Gaps = 1/254 (0%)
Frame = +2
Query: 1 MDDREDLVYQAKLAEQAERYDEMVESMKKVAGMDVELTVEERNLLSVAYKNVIGARRASW 60
M DRED VYQAK +AERYDEMV+ MK VA MDVELTVEERNLLSVAYKNVIGARRASW
Sbjct: 56 MGDREDQVYQAKQLNRAERYDEMVKFMKIVACMDVELTVEERNLLSVAYKNVIGARRASW 235
Query: 61 RIISSIEQKEENKGGEDKLKMIREYRQMVETELKLICCDILDVLDKHLIPAANTGESKVF 120
RI+SS+EQKE+ EDK + +EYR +E ELK IC D+LD+L+KHLI ANTGESKVF
Sbjct: 236 RIVSSLEQKEDK--CEDKKAINKEYRMKIEKELKDICEDVLDILEKHLIVNANTGESKVF 409
Query: 121 YYKMKGDYHRYLAEFATGNDRKEAAENSLVAYKAASDIAMTELPPTHPIRLGLALNFSVF 180
YYKMKGDYHRYLAEFA GNDRKEAAENSLVAYKAASDIAM EL PTHPIRLGLALNFSVF
Sbjct: 410 YYKMKGDYHRYLAEFAVGNDRKEAAENSLVAYKAASDIAMIELAPTHPIRLGLALNFSVF 589
Query: 181 YYEILNSPDRACRLAKAAFDDAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDMQGD-G 239
YYEILNSPDRACRLAKAAFDDAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDMQG+ G
Sbjct: 590 YYEILNSPDRACRLAKAAFDDAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDMQGEGG 769
Query: 240 EEQNKEALQDVEDE 253
EEQ+ + +QD+E E
Sbjct: 770 EEQSTQQVQDIEGE 811
>13465
Length = 596
Score = 239 bits (609), Expect = 1e-63, Method: Compositional matrix adjust.
Identities = 116/153 (75%), Positives = 132/153 (86%)
Frame = +2
Query: 1 MDDREDLVYQAKLAEQAERYDEMVESMKKVAGMDVELTVEERNLLSVAYKNVIGARRASW 60
M DR+D VYQAKLAEQAERYDEMVE+MKKVA M +LTVEERNLLSVAYKNVIGARRASW
Sbjct: 110 MTDRDDFVYQAKLAEQAERYDEMVEAMKKVASMGNDLTVEERNLLSVAYKNVIGARRASW 289
Query: 61 RIISSIEQKEENKGGEDKLKMIREYRQMVETELKLICCDILDVLDKHLIPAANTGESKVF 120
RI+SS+EQK+ +K DK KM + YRQ +ETELK IC D+L ++D HLIP+ GESKVF
Sbjct: 290 RIVSSVEQKDLDKPDPDKGKMTKGYRQQIETELKQICEDVLKIIDDHLIPSTTQGESKVF 469
Query: 121 YYKMKGDYHRYLAEFATGNDRKEAAENSLVAYK 153
YYKMKGDY+RYLAEFATG+ RKEAAE+SLVAYK
Sbjct: 470 YYKMKGDYYRYLAEFATGDPRKEAAESSLVAYK 568
>33715
Length = 434
Score = 175 bits (444), Expect = 1e-44, Method: Compositional matrix adjust.
Identities = 85/119 (71%), Positives = 95/119 (79%)
Frame = -1
Query: 123 KMKGDYHRYLAEFATGNDRKEAAENSLVAYKAASDIAMTELPPTHPIRLGLALNFSVFYY 182
KMKGDY+RYL+E + G RKE S+ AYK A+D+A L THPIRLGLALNFSVF+Y
Sbjct: 371 KMKGDYYRYLSEVSQGEQRKENVGKSMEAYKEATDMAKERLSSTHPIRLGLALNFSVFHY 192
Query: 183 EILNSPDRACRLAKAAFDDAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDMQGDGEE 241
EI N PD ACRLAK AFD+AI LD L+EESYKDSTLIMQLLRDNLTLWTSD QG+G E
Sbjct: 191 EIKNCPDEACRLAKIAFDEAIQCLDQLNEESYKDSTLIMQLLRDNLTLWTSDSQGEGTE 15
>17028
Length = 1078
Score = 124 bits (312), Expect = 3e-29, Method: Compositional matrix adjust.
Identities = 63/105 (60%), Positives = 78/105 (74%), Gaps = 2/105 (1%)
Frame = +1
Query: 142 KEAAENSLVAYKAASDIAMTELPPTHPIRLGLALNFSVFYYEILNSPDRACRLAKAAFDD 201
+EA + AY A ++A + PTHP RLGLALN+SVFYYEILNS D+AC LAK AFD+
Sbjct: 28 QEAVTKAQEAYNKAMEVAKQSMAPTHPNRLGLALNYSVFYYEILNSQDKACDLAKTAFDE 207
Query: 202 AIAELDTLSE-ESYKDSTLIMQLLRDNLTLWTSDMQG-DGEEQNK 244
AI E+D E + KDSTLIMQLLRDNLTLWTSD +G++Q++
Sbjct: 208 AIQEMDQCGERDDCKDSTLIMQLLRDNLTLWTSDSNAENGDDQDR 342
>15092
Length = 692
Score = 108 bits (271), Expect = 2e-24, Method: Compositional matrix adjust.
Identities = 61/109 (55%), Positives = 77/109 (70%), Gaps = 8/109 (7%)
Frame = +3
Query: 1 MDDREDLVYQAKLAEQAERYDEMVESMKKV------AGMDVELTV--EERNLLSVAYKNV 52
+ +E V+ AK+AEQAERYD+M ESM K A D T+ EERNLLSVAYKNV
Sbjct: 222 LSPKERQVHAAKIAEQAERYDDMAESMHKCVVEGYSANGDKSSTLDNEERNLLSVAYKNV 401
Query: 53 IGARRASWRIISSIEQKEENKGGEDKLKMIREYRQMVETELKLICCDIL 101
+GARR++WR+ISSIEQK EN + KL+M ++YR+ VE ELK IC +L
Sbjct: 402 VGARRSAWRVISSIEQKTEN--NDKKLEMAKKYREKVEKELKEICTQVL 542
>27988
Length = 448
Score = 59.3 bits (142), Expect(2) = 6e-16, Method: Compositional matrix adjust.
Identities = 30/60 (50%), Positives = 41/60 (68%)
Frame = +3
Query: 44 LLSVAYKNVIGARRASWRIISSIEQKEENKGGEDKLKMIREYRQMVETELKLICCDILDV 103
L SVAYKNV+GARR+SWR+I IEQK E + ++K R +R+ VE EL C ++L +
Sbjct: 276 LFSVAYKNVVGARRSSWRVICMIEQKAETQPRKEK---ARAFRKDVEKELDATCNEVLKL 446
Score = 41.6 bits (96), Expect(2) = 6e-16, Method: Compositional matrix adjust.
Identities = 22/38 (57%), Positives = 27/38 (71%)
Frame = +2
Query: 5 EDLVYQAKLAEQAERYDEMVESMKKVAGMDVELTVEER 42
+DL+ AKLAEQAERYD+M ++MKKV D L E R
Sbjct: 158 KDLISFAKLAEQAERYDDMAKAMKKVTENDKTLMQESR 271
>18027
Length = 448
Score = 28.1 bits (61), Expect = 3.2, Method: Compositional matrix adjust.
Identities = 14/44 (31%), Positives = 27/44 (61%)
Frame = +1
Query: 211 EESYKDSTLIMQLLRDNLTLWTSDMQGDGEEQNKEALQDVEDEN 254
EE + +T+ +Q + D L WT ++G+G E ++ A++D + N
Sbjct: 307 EEQFGKNTISLQYVPDLLACWTLHVRGEGGE-DRHAIEDNQHVN 435
>05069
Length = 1988
Score = 27.7 bits (60), Expect = 5.1, Method: Compositional matrix adjust.
Identities = 11/26 (42%), Positives = 17/26 (65%)
Frame = +2
Query: 99 DILDVLDKHLIPAANTGESKVFYYKM 124
DI + + + PAANT +K+FYY +
Sbjct: 1871 DI*NDVSSTITPAANTNRNKIFYYMI 1948
>01750
Length = 1886
Score = 27.3 bits (59), Expect = 6.0, Method: Compositional matrix adjust.
Identities = 24/79 (30%), Positives = 40/79 (50%), Gaps = 2/79 (2%)
Frame = +2
Query: 20 YDEMVESMKKVAGMDVELT--VEERNLLSVAYKNVIGARRASWRIISSIEQKEENKGGED 77
Y E E+ K A DV + V ++N YK V+ AR W++ SIE+ K ED
Sbjct: 440 YKEKGETPPKRA-FDVAVKEWVVQQNSNRPVYKTVV-ARPVDWKV-PSIERMWLGKSDED 610
Query: 78 KLKMIREYRQMVETELKLI 96
K + +R + ++ ++ L+
Sbjct: 611 KNRRLRAFLTIMHSDSNLV 667
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000265563 | hsapiens_gene_ensembl | cAMP-dependent
protein kinase type II-alpha regulatory subunit.
[Source:Uniprot/SWISSPROT;Acc:P13861]
(404 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
08195 405 e-113
27710 133 1e-31
18204 95 6e-20
20517 50 2e-06
27853 36 0.026
27148 29 3.9
>08195
Length = 2165
Score = 405 bits (1040), Expect = e-113, Method: Compositional matrix adjust.
Identities = 202/401 (50%), Positives = 268/401 (66%), Gaps = 4/401 (0%)
Frame = -3
Query: 6 IPPGLTELLQGYTVEVLRQQPPDLVEFAVEYFTRLR----EARAPASVLPAATPRQSLGH 61
IPPGLTELLQ +TV LR++P DLV+FA YF RLR +A P Q+ H
Sbjct: 2019 IPPGLTELLQEFTVAALRERPSDLVDFAASYFNRLRLLNGDAVDPKCFTGGVRFSQTGSH 1840
Query: 62 PPPEPGPDRVADAKGXXXXXXXXXXXXXXXXRFNRRVSVCAETYNPDEEEEDTDPRVIHP 121
G RF RR SV AE YNP+ +E+ + ++++P
Sbjct: 1839 ILAHNG---TFAQNNSDDDEAMLEPPPSNTARF-RRKSVSAEAYNPETDEDGGEAKIVNP 1672
Query: 122 KTDEQRCRLQEACKDILLFKNLDQEQLSQVLDAMFERIVKADEHVIDQGDDGDNFYVIER 181
K+D QR RL + K+ILLF++LD EQ+ +VLDAMFE+ V+ EH+IDQGDDGDNFYVI+
Sbjct: 1671 KSDIQRQRLADVVKNILLFRSLDPEQMQEVLDAMFEKSVQPGEHIIDQGDDGDNFYVIDS 1492
Query: 182 GTYDILVTKDNQTRSVGQYDNRGSFGELALMYNTPRAATIVATSEGSLWGLDRVTFRRII 241
GTYDI V + Q + VG YDN G FGELALMYN PRAATI+A+S G++W LDR TFRRI+
Sbjct: 1491 GTYDIYVDVEGQAKLVGNYDNSGFFGELALMYNMPRAATIIASSTGTIWALDRTTFRRIV 1312
Query: 242 VKNNAKKRKMFESFIESVPLLKSLEVSERMKIVDVIGEKIYKDGERIITQGEKADSFYII 301
+K +KRK +ES +ESVPLLKSL++ ERM + D + + Y+DG +II QG+ AD Y +
Sbjct: 1311 LKTAFQKRKKYESLLESVPLLKSLDLYERMNVADALQTRTYEDGVQIIKQGDAADVMYFV 1132
Query: 302 ESGEVSILIRSRTKSNKDGGNQEVEIARCHKGQYFGELALVTNKPRAASAYAVGDVKCLV 361
ESG+V I + ++ ++ G E ++ KG YFGELAL+T++PRAASAYA G VKC V
Sbjct: 1131 ESGQVRIAMTNKESTDPSAG--ETDVTVLEKGGYFGELALITHQPRAASAYAQGTVKCAV 958
Query: 362 MDVQAFERLLGPCMDIMKRNISHYEEQLVKMFGSSVDLGNL 402
+DV AFERL+GPCMD++KRNI Y+ Q+ +FG SV + ++
Sbjct: 957 LDVHAFERLMGPCMDVLKRNIDDYDSQISSIFGKSVSMKDM 835
>27710
Length = 429
Score = 133 bits (334), Expect = 1e-31, Method: Compositional matrix adjust.
Identities = 67/146 (45%), Positives = 94/146 (64%)
Frame = +2
Query: 164 EHVIDQGDDGDNFYVIERGTYDILVTKDNQTRSVGQYDNRGSFGELALMYNTPRAATIVA 223
E++I QGD+GDNFYVI+ G D+ V + V GSFGELAL+Y TPRAAT+ A
Sbjct: 2 ENIIQQGDEGDNFYVIDVGEVDVFV----NSELVTTISEGGSFGELALIYGTPRAATVRA 169
Query: 224 TSEGSLWGLDRVTFRRIIVKNNAKKRKMFESFIESVPLLKSLEVSERMKIVDVIGEKIYK 283
S+ LWG+DR ++RRI++ + +KRKM+E F+ V +L+SL+ ER+ + D + +
Sbjct: 170 KSDVKLWGIDRDSYRRILMGSTIRKRKMYEEFLSRVSILESLDKWERLTVADSLETCAFD 349
Query: 284 DGERIITQGEKADSFYIIESGEVSIL 309
DGE I+ QG D FYII G +L
Sbjct: 350 DGETIVKQGAAGDDFYIILEGCAVVL 427
Score = 59.3 bits (142), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 37/107 (34%), Positives = 54/107 (50%)
Frame = +2
Query: 286 ERIITQGEKADSFYIIESGEVSILIRSRTKSNKDGGNQEVEIARCHKGQYFGELALVTNK 345
E II QG++ D+FY+I+ GEV + + S + +G FGELAL+
Sbjct: 2 ENIIQQGDEGDNFYVIDVGEVDVFVNSEL------------VTTISEGGSFGELALIYGT 145
Query: 346 PRAASAYAVGDVKCLVMDVQAFERLLGPCMDIMKRNISHYEEQLVKM 392
PRAA+ A DVK +D ++ R+L M R YEE L ++
Sbjct: 146 PRAATVRAKSDVKLWGIDRDSYRRIL---MGSTIRKRKMYEEFLSRV 277
Score = 32.3 bits (72), Expect = 0.38, Method: Compositional matrix adjust.
Identities = 19/77 (24%), Positives = 38/77 (49%)
Frame = +2
Query: 111 EEDTDPRVIHPKTDEQRCRLQEACKDILLFKNLDQEQLSQVLDAMFERIVKADEHVIDQG 170
+ D+ R++ T +R +E + + ++LD+ + V D++ E ++ QG
Sbjct: 197 DRDSYRRILMGSTIRKRKMYEEFLSRVSILESLDKWERLTVADSLETCAFDDGETIVKQG 376
Query: 171 DDGDNFYVIERGTYDIL 187
GD+FY+I G +L
Sbjct: 377 AAGDDFYIILEGCAVVL 427
>18204
Length = 429
Score = 94.7 bits (234), Expect = 6e-20, Method: Compositional matrix adjust.
Identities = 53/149 (35%), Positives = 83/149 (55%)
Frame = -1
Query: 205 SFGELALMYNTPRAATIVATSEGSLWGLDRVTFRRIIVKNNAKKRKMFESFIESVPLLKS 264
+FGELA++YN R A++ A ++ +W LDR F+ I++K ++R+ F++SV +L+
Sbjct: 429 AFGELAILYNCTRTASVKAVTDVKVWVLDRQMFQAIMMKTGLQRREENIRFLKSVSVLRD 250
Query: 265 LEVSERMKIVDVIGEKIYKDGERIITQGEKADSFYIIESGEVSILIRSRTKSNKDGGNQE 324
L + KI DV+ + +GE II +G D+F++I GEV R G +
Sbjct: 249 LPSDKLAKIADVLEIDFFHEGEFIIREGCTGDTFFLINKGEV------RVTQTVAGHEEP 88
Query: 325 VEIARCHKGQYFGELALVTNKPRAASAYA 353
EI + +G YFGE AL+ R AS A
Sbjct: 87 QEIRKLKRGDYFGEKALLGEDRRTASCIA 1
Score = 39.3 bits (90), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 22/54 (40%), Positives = 30/54 (55%)
Frame = -1
Query: 336 FGELALVTNKPRAASAYAVGDVKCLVMDVQAFERLLGPCMDIMKRNISHYEEQL 389
FGELA++ N R AS AV DVK V+D Q F+ ++ MK + EE +
Sbjct: 426 FGELAILYNCTRTASVKAVTDVKVWVLDRQMFQAIM------MKTGLQRREENI 283
>20517
Length = 749
Score = 49.7 bits (117), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 43/171 (25%), Positives = 79/171 (46%), Gaps = 11/171 (6%)
Frame = +3
Query: 175 NFYVIERGTYDILVTK----DNQTRSVGQYDNRGSFGELALMYNTPRAATIVATSEGSLW 230
+FY I GT ++VT+ + TR++ D SFGELA++ + R AT+ +E L
Sbjct: 18 SFYFILSGT--VVVTQFERQYSTTRTLVTLDQGMSFGELAVITGSRRQATVSTMTEVELL 191
Query: 231 GLDRVTFRRIIVKNNAKKRKMF-----ESFIESVPLLKSLEVSERMKIVDVIGEKIYKDG 285
+ F I + A RK+ F+ SV LK+ V + + + G
Sbjct: 192 CISAKDFEDIFM---AGGRKIITDPDHNKFLRSVDFLKAWPVQQLAQHPHACMFHYFNRG 362
Query: 286 ERIITQGEKADSFYIIESGEVSIL--IRSRTKSNKDGGNQEVEIARCHKGQ 334
+ ++ +D YI++SG +S++ + T +++ + E+A K +
Sbjct: 363 QVLVRDSNNSDWIYIVKSGSLSVMKKLHHATATDRHSTEGKSEVAEASKSK 515
>27853
Length = 864
Score = 36.2 bits (82), Expect = 0.026, Method: Compositional matrix adjust.
Identities = 28/123 (22%), Positives = 58/123 (47%)
Frame = +2
Query: 280 KIYKDGERIITQGEKADSFYIIESGEVSILIRSRTKSNKDGGNQEVEIARCHKGQYFGEL 339
++ + G+ + QG+ +DS YI+ +G R R+ GG +EV + +G+ G +
Sbjct: 227 QMTEAGKALFRQGDNSDSVYIVLTG------RLRSVITLLGGKKEV-VGEYGRGELVGIV 385
Query: 340 ALVTNKPRAASAYAVGDVKCLVMDVQAFERLLGPCMDIMKRNISHYEEQLVKMFGSSVDL 399
++T+ RA + A+ D + ++ + ++K +L+ + G + L
Sbjct: 386 EVLTHTERATTNMAIRDTEV--------AKIPEELLTLIKLKYPQVVTRLIHLLGQRI-L 538
Query: 400 GNL 402
GNL
Sbjct: 539 GNL 547
Score = 28.1 bits (61), Expect = 7.0, Method: Compositional matrix adjust.
Identities = 18/71 (25%), Positives = 37/71 (52%), Gaps = 1/71 (1%)
Frame = +2
Query: 154 AMFERIVKADEHVIDQGDDGDNFYVIERGTYDILVT-KDNQTRSVGQYDNRGSFGELALM 212
A+ ++ +A + + QGD+ D+ Y++ G ++T + VG+Y G + ++
Sbjct: 215 ALDWQMTEAGKALFRQGDNSDSVYIVLTGRLRSVITLLGGKKEVVGEYGRGELVGIVEVL 394
Query: 213 YNTPRAATIVA 223
+T RA T +A
Sbjct: 395 THTERATTNMA 427
>27148
Length = 718
Score = 28.9 bits (63), Expect = 3.9, Method: Compositional matrix adjust.
Identities = 14/25 (56%), Positives = 19/25 (76%), Gaps = 1/25 (4%)
Frame = -3
Query: 200 YDNRG-SFGELALMYNTPRAATIVA 223
Y NRG SFGELA+M T R +T+++
Sbjct: 293 YYNRGDSFGELAIMNATRRQSTVIS 219
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000364801 | hsapiens_gene_ensembl | Heat shock 70
kDa protein 1 (HSP70.1) (HSP70-1/HSP70-2).
[Source:Uniprot/SWISSPROT;Acc:P08107]
(641 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
30255 310 e-113
21024 241 8e-64
37715 147 9e-56
27378 202 4e-52
26390 178 5e-45
24750 135 7e-32
06909 96 9e-25
31218 95 8e-20
09881 93 4e-19
20979 89 7e-18
12271 62 6e-10
13684 58 1e-08
03996 55 9e-08
13300 45 6e-05
34036 42 6e-04
>30255
Length = 1761
Score = 310 bits (794), Expect(2) = e-113, Method: Compositional matrix adjust.
Identities = 153/199 (76%), Positives = 165/199 (82%)
Frame = -1
Query: 328 KAQIHDLVLVGGSTRIPKVQKLLQDFFNGRDLNKSINPDEXXXXXXXXXXXILMGDKSEN 387
K IH++VLVGGSTRIPK+QKLLQDFFNG++L KSINPDE IL GDKSE
Sbjct: 1644 KPGIHEIVLVGGSTRIPKIQKLLQDFFNGKELCKSINPDEAVAYGACVQAAILHGDKSEE 1465
Query: 388 VQDXXXXXXXXXXXXXETAGGVMTALIKRNSTIPTKQTQIFTTYSDNQPGVLIQVYEGER 447
VQD ETAGGVMTALIKRN+TIPTKQTQ FTTYSDNQPGVLIQVYEGER
Sbjct: 1464 VQDLLLLDVAPLSMGIETAGGVMTALIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGER 1285
Query: 448 AMTKDNNLLGRFELSGIPPAPRGVPQIEVTFDIDANGILNVTATDKSTGKANKITITNDK 507
AMT+DNNLLG+FEL+GIPPAPRGVPQIEVTFDIDANGILNV+A DKSTGK NKITITNDK
Sbjct: 1284 AMTRDNNLLGKFELTGIPPAPRGVPQIEVTFDIDANGILNVSAADKSTGKENKITITNDK 1105
Query: 508 GRLSKEEIERMVQEAEKYK 526
GRLSKEEIERMV +AEK +
Sbjct: 1104 GRLSKEEIERMVNDAEKSR 1048
Score = 117 bits (292), Expect(2) = e-113, Method: Compositional matrix adjust.
Identities = 53/77 (68%), Positives = 66/77 (85%)
Frame = -3
Query: 535 RVSAKNALESYAFNMKSAVEDEGLKGKISEADKKKVLDKCQEVISWLDANTLAEKDEFEH 594
R+S+KN+LESYAF+MKS +EDE +K KI E DKK ++DKC EVISWLDAN AEKDE++
Sbjct: 1024 RISSKNSLESYAFHMKSTIEDEKIKDKIGEEDKKTIVDKCNEVISWLDANQTAEKDEYDD 845
Query: 595 KRKELEQVCNPIISGLY 611
K+KELE+VCNPII+ LY
Sbjct: 844 KQKELEKVCNPIITKLY 794
>21024
Length = 3220
Score = 241 bits (614), Expect = 8e-64, Method: Compositional matrix adjust.
Identities = 164/424 (38%), Positives = 235/424 (55%), Gaps = 8/424 (1%)
Frame = +1
Query: 166 GLNVLRIINEPTAAAIAYGLDRTGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGD 225
G NVLR+INEPTAAA+A + + + + F DV L + D V +
Sbjct: 727 G*NVLRVINEPTAAALALWHGQV*R*SDSGV*FR----RRDV*HLYLGDPEGSV*SQINQ 894
Query: 226 T-HLGGEDFDNRLVNHFVEEFK---RKHKKDISQNKRAVRRLRTACERAKRTLSSSTQAS 281
H+ G L + + RK K SQ + + R +++K LSSS Q
Sbjct: 895 RRHIPGRR--GLLTTTWSTSWHQNLRKSKD*TSQRIQWLCRDYVRQQKSKIELSSSLQTD 1068
Query: 282 LEIDSLFEGID----FYTSITRARFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDLVLV 337
+ + L ++R++FE L L + T+ P +KAL+DA++ K+ I +++LV
Sbjct: 1069 INLPYLTMDASGPKHMNLKLSRSKFESLVESLVKRTVGPCQKALQDAEVKKSDIGEVILV 1248
Query: 338 GGSTRIPKVQKLLQDFFNGRDLNKSINPDEXXXXXXXXXXXILMGDKSENVQDXXXXXXX 397
GG +R+PKVQ +QD F GR +KS+NPDE +L GD V D
Sbjct: 1249 GGMSRMPKVQSTVQDLF-GRTPSKSVNPDEAVAIGAAIQGGVLAGD----VTDVLLLDVT 1413
Query: 398 XXXXXXETAGGVMTALIKRNSTIPTKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLG 457
ET GGV T LI RN+TIPTK++Q+F+T +D Q V I+V++GER M DN LLG
Sbjct: 1414 PLSLGIETLGGVFTKLINRNTTIPTKKSQVFSTAADGQTQVEIKVHQGEREMANDNKLLG 1593
Query: 458 RFELSGIPPAPRGVPQIEVTFDIDANGILNVTATDKSTGKANKITITNDKGRLSKEEIER 517
+F L GIPPAPRGVPQ+EVTFDIDANGI+NV+A DK TGK +I I + G LSK+EIE
Sbjct: 1594 QFTLVGIPPAPRGVPQVEVTFDIDANGIVNVSARDKGTGKEQQIVIQSSGG-LSKDEIEN 1770
Query: 518 MVQEAEKYKAEDEVQRERVSAKNALESYAFNMKSAVEDEGLKGKISEADKKKVLDKCQEV 577
M++ AE + +D ++E V N +S + +S +E+ K ++ + + K+ +K EV
Sbjct: 1771 MIKNAEAHAEDDRRKKELVEVLNQADSIIHDTESKMEE--FKDQLPQEECDKLREKINEV 1944
Query: 578 ISWL 581
L
Sbjct: 1945 KQLL 1956
Score = 184 bits (467), Expect = 1e-46, Method: Compositional matrix adjust.
Identities = 110/271 (40%), Positives = 160/271 (59%), Gaps = 4/271 (1%)
Frame = +3
Query: 3 KAAAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQVAL 61
K IGIDLGTT SCV + + + +++ N +G+RTTPS +AFT D ER+ G AK Q
Sbjct: 243 KGHVIGIDLGTTNSCVALMEGKQAKVLENSEGSRTTPSVIAFTKDGERISGMPAKRQAVT 422
Query: 62 NPQNTVFDAKRLIGRKFGDPVVQSDMKHWPFQVI--NDGDKPKVQVSYKGETKAFYPEEI 119
N +NT+ KRLIGR+F DP VQ DMK+ ++++ ++GD + + K + P ++
Sbjct: 423 NAENTLSATKRLIGRRFEDPEVQKDMKNVSYKIVKASNGD-----AWVEAQGKMYSPSQV 587
Query: 120 SSMVLTKMKEIAEAYLGYPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAA 179
+ VL KMKE AE+YLG V NAV+TVPAYFNDSQRQATKDAG I+GL + +
Sbjct: 588 GAFVLMKMKETAESYLGSKVNNAVVTVPAYFNDSQRQATKDAGQISGLKCVACDQRTHSC 767
Query: 180 AIAYGLDRTGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGE-DFDNRLV 238
+ + + K + + G +S + + + + T +TH E FDN +V
Sbjct: 768 SSCFMAWTSLKIK**RCLI*AEGRLTSLSWRSRRECLKSNQPT--ETHSWEERTFDNYMV 941
Query: 239 NHFVEEFKRKHKKDISQNKRAVRRLRTACER 269
N EFK++ DI+++ AV+RLR A E+
Sbjct: 942 NFLASEFKKEQGLDITKDPMAVQRLREAAEK 1034
>37715
Length = 468
Score = 147 bits (370), Expect(2) = 9e-56, Method: Compositional matrix adjust.
Identities = 69/96 (71%), Positives = 80/96 (83%)
Frame = -2
Query: 92 FQVINDGDKPKVQVSYKGETKAFYPEEISSMVLTKMKEIAEAYLGYPVTNAVITVPAYFN 151
+VIN +KP +Q G TK F PEEIS+MVL KM++IAEAYLG + NAV+TVPAYFN
Sbjct: 458 LKVINKSNKPHIQALVSGATKTFAPEEISAMVLGKMRDIAEAYLGKKIDNAVVTVPAYFN 279
Query: 152 DSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDR 187
D+QRQATKDAG IAGLNV+RIINEPTAAAIAYGLD+
Sbjct: 278 DAQRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDK 171
Score = 89.0 bits (219), Expect(2) = 9e-56, Method: Composition-based stats.
Identities = 37/52 (71%), Positives = 48/52 (92%)
Frame = -1
Query: 194 NVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVNHFVEEF 245
N+L+FDLGGGTFDVS+LTID+G+FEV AT GDTHLGGEDFD R+++HF++ +
Sbjct: 156 NILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMDHFIKLY 1
>27378
Length = 410
Score = 202 bits (513), Expect = 4e-52, Method: Compositional matrix adjust.
Identities = 95/124 (76%), Positives = 108/124 (87%)
Frame = -1
Query: 244 EFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDSLFEGIDFYTSITRARFE 303
EFKRK+KKD+ N RA+RRLRTA ERAKRTLSSST+A++E+D+LFEG DFYT I+RARFE
Sbjct: 410 EFKRKYKKDLRSNPRALRRLRTAAERAKRTLSSSTEATIEVDALFEGHDFYTKISRARFE 231
Query: 304 ELCSDLFRSTLEPVEKALRDAKLDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGRDLNKSI 363
ELC+DLFR TL PVEKAL DAK+DK IHD+VLVGGSTRIPKVQ LLQ FF G+ LN SI
Sbjct: 230 ELCADLFRQTLAPVEKALNDAKMDKQMIHDIVLVGGSTRIPKVQNLLQQFFGGKSLNLSI 51
Query: 364 NPDE 367
NPDE
Sbjct: 50 NPDE 39
>26390
Length = 665
Score = 178 bits (452), Expect = 5e-45, Method: Compositional matrix adjust.
Identities = 84/152 (55%), Positives = 109/152 (71%)
Frame = +2
Query: 404 ETAGGVMTALIKRNSTIPTKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFELSG 463
ET GGVMT LI R +TIP ++ ++F+T DNQ V IQVYEGER+ TKDN+LLGRF+L+G
Sbjct: 56 ETVGGVMTTLIARGTTIPARKAKVFSTAQDNQDSVTIQVYEGERSRTKDNHLLGRFDLTG 235
Query: 464 IPPAPRGVPQIEVTFDIDANGILNVTATDKSTGKANKITITNDKGRLSKEEIERMVQEAE 523
IP APRGVPQIEVTF +DANG++ V+A DK TG+ N I I LS E++ERMVQEA+
Sbjct: 236 IPAAPRGVPQIEVTFQVDANGVMQVSAEDKGTGQKNDIIIQQSGSGLSPEDVERMVQEAQ 415
Query: 524 KYKAEDEVQRERVSAKNALESYAFNMKSAVED 555
+ ED RE ++ LES A+ + ++D
Sbjct: 416 DFAEEDRKFRELTESRTGLESLAYTAQHQLQD 511
>24750
Length = 552
Score = 135 bits (339), Expect = 7e-32, Method: Compositional matrix adjust.
Identities = 62/71 (87%), Positives = 69/71 (97%)
Frame = +1
Query: 439 LIQVYEGERAMTKDNNLLGRFELSGIPPAPRGVPQIEVTFDIDANGILNVTATDKSTGKA 498
++QVYEGERAMT+DNNLLG+FEL+GIPPAPRGVPQIEVTFDIDANGILNV+A DKSTGK
Sbjct: 154 MLQVYEGERAMTRDNNLLGKFELTGIPPAPRGVPQIEVTFDIDANGILNVSAADKSTGKE 333
Query: 499 NKITITNDKGR 509
NKITITNDKG+
Sbjct: 334 NKITITNDKGQ 366
>06909
Length = 456
Score = 95.9 bits (237), Expect(2) = 9e-25, Method: Compositional matrix adjust.
Identities = 43/65 (66%), Positives = 54/65 (83%)
Frame = -3
Query: 547 FNMKSAVEDEGLKGKISEADKKKVLDKCQEVISWLDANTLAEKDEFEHKRKELEQVCNPI 606
+MKS +EDE +K KIS DKK +LDKC EVI+WLDAN LAEKDE++ K+KE+E+VCNPI
Sbjct: 388 LHMKSTIEDEKIKDKISTEDKKTILDKCDEVIAWLDANQLAEKDEYDDKQKEIEKVCNPI 209
Query: 607 ISGLY 611
I+ LY
Sbjct: 208 ITKLY 194
Score = 36.2 bits (82), Expect(2) = 9e-25, Method: Compositional matrix adjust.
Identities = 16/23 (69%), Positives = 20/23 (86%)
Frame = -1
Query: 524 KYKAEDEVQRERVSAKNALESYA 546
KYK +DE Q+ R+SAKN+LESYA
Sbjct: 456 KYKEDDEKQKSRISAKNSLESYA 388
>31218
Length = 322
Score = 95.1 bits (235), Expect = 8e-20, Method: Compositional matrix adjust.
Identities = 49/100 (49%), Positives = 70/100 (70%)
Frame = +2
Query: 225 DTHLGGEDFDNRLVNHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEI 284
DTHLGGEDFD RLV++ V+ K+K +D+ + RA+ RLR + E+AKR LSS +++
Sbjct: 2 DTHLGGEDFDQRLVDYLVKLIKQKTGRDVRHDTRAMSRLRRSAEKAKRALSSQHSTKVDL 181
Query: 285 DSLFEGIDFYTSITRARFEELCSDLFRSTLEPVEKALRDA 324
D + + T +TRA+FEEL +DLFRSTL V++AL D+
Sbjct: 182 DGVTSDLADLT-LTRAKFEELNTDLFRSTLTTVKRALEDS 298
>09881
Length = 600
Score = 92.8 bits (229), Expect = 4e-19, Method: Composition-based stats.
Identities = 44/109 (40%), Positives = 67/109 (61%)
Frame = +3
Query: 3 KAAAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVALN 62
K AA G+ LGT +C+ V++ GK + AND G+R+TP VAFT + +G +AK + N
Sbjct: 177 KMAAYGVHLGTCSACLAVYKDGKTSVAANDAGDRSTPCVVAFTACDAEVGASAKQGIVSN 356
Query: 63 PQNTVFDAKRLIGRKFGDPVVQSDMKHWPFQVINDGDKPKVQVSYKGET 111
+NTV + KR++G F DPV Q + P +V+N ++P +V +K T
Sbjct: 357 VKNTVCNVKRILGLTFEDPVTQEYLASSPVKVVNQKNQPMFEVEFKERT 503
Score = 47.4 bits (111), Expect = 2e-05, Method: Composition-based stats.
Identities = 26/53 (49%), Positives = 35/53 (66%)
Frame = +2
Query: 136 GYPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDRT 188
G + +AV+ VP+ F+D QR A A AG VLR+INE +AAA+AY L +T
Sbjct: 2 GKGIQDAVLAVPSDFSDKQRAAASAAASKAGFKVLRLINECSAAALAYDLGQT 160
>20979
Length = 976
Score = 88.6 bits (218), Expect = 7e-18, Method: Compositional matrix adjust.
Identities = 47/140 (33%), Positives = 80/140 (57%), Gaps = 2/140 (1%)
Frame = +1
Query: 230 GEDFDNRLVNHFVEEFKRKHKKD--ISQNKRAVRRLRTACERAKRTLSSSTQASLEIDSL 287
G + RL +H + F + K+ + N RA+ +L ER K+ LS+++ +++ L
Sbjct: 70 GVEMTLRLRDHLAKVFNGQKKRSFKLEDNPRAMAKLLKEAERVKKVLSANSDHKAQVEGL 249
Query: 288 FEGIDFYTSITRARFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDLVLVGGSTRIPKVQ 347
EG DF ++R + EL DL +P+E AL+ +++ +I +++L+GG +R+P+VQ
Sbjct: 250 VEGEDFAAKVSREDYLELIKDLLARVTKPMEDALKVSEITMPEITEIILMGGGSRVPRVQ 429
Query: 348 KLLQDFFNGRDLNKSINPDE 367
+ L F DL KSIN DE
Sbjct: 430 EELLKFSGKSDLGKSINTDE 489
>12271
Length = 1762
Score = 62.4 bits (150), Expect = 6e-10, Method: Compositional matrix adjust.
Identities = 26/76 (34%), Positives = 48/76 (63%)
Frame = +2
Query: 292 DFYTSITRARFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDLVLVGGSTRIPKVQKLLQ 351
DF +TR ++ L DL PV++ L +++ A+I +++L+GG +R+PK+ ++L
Sbjct: 41 DFSCKVTRDKYLHLIQDLLDRVTLPVQQVLTASQITWAEITEIILMGGGSRLPKIHEILL 220
Query: 352 DFFNGRDLNKSINPDE 367
D+ ++L KS+N DE
Sbjct: 221 DYSGKKELGKSLNTDE 268
Score = 29.6 bits (65), Expect = 4.3, Method: Compositional matrix adjust.
Identities = 17/83 (20%), Positives = 41/83 (49%), Gaps = 1/83 (1%)
Frame = +1
Query: 500 KITI-TNDKGRLSKEEIERMVQEAEKYKAEDEVQRERVSAKNALESYAFNMKSAVEDEGL 558
K+T+ D LSK+++++ + ++ DE + A+N +ES+ + + +E
Sbjct: 982 KVTVKVKDMAELSKDQVKQSKKRLTDWRKRDEEKAAVQKARNEVESFIITAQDKMSEETY 1161
Query: 559 KGKISEADKKKVLDKCQEVISWL 581
++ ++ +LD+ + WL
Sbjct: 1162 LASSTDEERAXILDQLSQASDWL 1230
>13684
Length = 438
Score = 57.8 bits (138), Expect = 1e-08, Method: Composition-based stats.
Identities = 26/60 (43%), Positives = 38/60 (63%)
Frame = -3
Query: 3 KAAAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVALN 62
K AA G+ LGT +C+ V++ GK + AND G+R+TP VAFT + +G +AK + N
Sbjct: 181 KMAAYGVHLGTCSACLAVYKDGKTSVAANDAGDRSTPCVVAFTACDAEVGASAKQGIVSN 2
>03996
Length = 1105
Score = 55.1 bits (131), Expect = 9e-08, Method: Compositional matrix adjust.
Identities = 26/64 (40%), Positives = 41/64 (64%)
Frame = -2
Query: 304 ELCSDLFRSTLEPVEKALRDAKLDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGRDLNKSI 363
EL DL +P+E AL+ +++ +I +++L+GG +R+P+VQ+ L F DL KSI
Sbjct: 1056 ELIKDLLARVTKPMEDALKVSEITMPEITEIILMGGGSRVPRVQEELLKFSGKSDLGKSI 877
Query: 364 NPDE 367
N DE
Sbjct: 876 NTDE 865
>13300
Length = 453
Score = 45.4 bits (106), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 34/149 (22%), Positives = 70/149 (46%), Gaps = 17/149 (11%)
Frame = +3
Query: 154 QRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDRT---GKGERNVLIFDLGGGTFDVSIL 210
+R+A A G+NVL+++ + A A+ YG+ R + + +D+G + +++
Sbjct: 3 ERRAIMTAADXVGINVLQLMTDSAAVALNYGVFRRKNFNTTAQYYMFYDMGATSTVATVV 182
Query: 211 T-----IDDGI-------FEVKATAGDTHLGGEDFDNRLVNHFVEEFKRKHKKD--ISQN 256
+ + +G +K D LGG + RL +H + F + K+ + N
Sbjct: 183 SYQVVKVKEGTRVESNPQLTIKGVGFDRTLGGLEMTLRLRDHLAKVFNGQKKRSFKLEDN 362
Query: 257 KRAVRRLRTACERAKRTLSSSTQASLEID 285
RA+ +L ER K+ LS+++ +++
Sbjct: 363 PRAMAKLLKEAERVKKVLSANSDHKAQVE 449
>34036
Length = 363
Score = 42.4 bits (98), Expect = 6e-04, Method: Composition-based stats.
Identities = 16/24 (66%), Positives = 22/24 (91%)
Frame = +2
Query: 588 EKDEFEHKRKELEQVCNPIISGLY 611
EKDE++ K+KE+E+VCNPII+ LY
Sbjct: 2 EKDEYDDKQKEIEKVCNPIITKLY 73
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000217244 | hsapiens_gene_ensembl | Casein kinase
II subunit alpha (EC 2.7.11.1) (CK II).
[Source:Uniprot/SWISSPROT;Acc:P68400]
(391 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
03508 402 e-112
00638 145 4e-47
12704 125 2e-29
01060 106 2e-23
14126 103 8e-23
01707 97 2e-20
04591 91 9e-19
04138 87 1e-17
29581 86 3e-17
32000 85 4e-17
01756 77 1e-14
21079 76 2e-14
15910 70 1e-12
23319 69 4e-12
26560 69 4e-12
00300 62 3e-10
12721 62 5e-10
13212 61 6e-10
12786 61 7e-10
01392 60 1e-09
30755 60 1e-09
28638 60 2e-09
01966 60 2e-09
14420 57 9e-09
27405 57 1e-08
18921 57 2e-08
31885 55 4e-08
03294 55 4e-08
19761 55 5e-08
26711 55 5e-08
18484 55 6e-08
09606 54 9e-08
19094 54 1e-07
18287 54 1e-07
13592 53 2e-07
18401 50 1e-06
03240 50 2e-06
21433 49 3e-06
13078 49 5e-06
31489 47 9e-06
13066 47 2e-05
04852 47 2e-05
07940 46 3e-05
11185 45 7e-05
00715 44 1e-04
17975 42 4e-04
37602 41 9e-04
14116 41 0.001
01718 40 0.001
01106 39 0.003
26009 39 0.004
05084 38 0.006
00392 38 0.006
06358 38 0.006
21800 37 0.014
32359 28 0.023
27546 36 0.030
02638 35 0.045
28157 35 0.060
18481 35 0.062
29360 34 0.10
15931 33 0.14
19301 33 0.18
26909 33 0.20
29590 33 0.24
11801 33 0.24
14104 33 0.27
12672 31 0.90
27274 30 1.2
35032 30 1.5
37063 30 1.6
17932 30 1.8
16350 30 2.0
20773 29 2.9
20513 29 3.5
18663 29 4.0
28419 28 6.1
20152 28 8.3
>03508
Length = 1463
Score = 402 bits (1032), Expect = e-112, Method: Compositional matrix adjust.
Identities = 187/233 (80%), Positives = 201/233 (86%)
Frame = +1
Query: 1 MSGPVPSRARVYTDVNTHRPREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINIT 60
+S P+PSRARVY DVNTH+ REYWDYESHVVEWGNQDDYQ+VRKLGRGKYSEVFEAIN+T
Sbjct: 481 VSMPLPSRARVYADVNTHKAREYWDYESHVVEWGNQDDYQIVRKLGRGKYSEVFEAINVT 660
Query: 61 NNEXXXXXXXXXXXXXXXXXXXXXLENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTD 120
NNE LENLRGG N+ITL IVKDPVSRTPAL+FEHVNNTD
Sbjct: 661 NNEKCVIKILKPVKKKKIKREIKILENLRGGTNVITLLAIVKDPVSRTPALIFEHVNNTD 840
Query: 121 FKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAE 180
FKQLYQT TDYDIRFY+YE++KALD+CHSMGIMHRDVKPHNVMIDHE++KLRLIDWGLAE
Sbjct: 841 FKQLYQTFTDYDIRFYLYELMKALDFCHSMGIMHRDVKPHNVMIDHENKKLRLIDWGLAE 1020
Query: 181 FYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFF 233
FYHPG EYNVRVASRYFKGPELL+DYQMYDYSLDMWSLGCM ASMIFRKEP
Sbjct: 1021FYHPGMEYNVRVASRYFKGPELLLDYQMYDYSLDMWSLGCMFASMIFRKEPLL 1179
Score = 186 bits (471), Expect = 2e-47, Method: Compositional matrix adjust.
Identities = 89/115 (77%), Positives = 97/115 (84%), Gaps = 3/115 (2%)
Frame = +2
Query: 216 WSLGCMLASM---IFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDI 272
W+ G A + K PFFHGHDNYDQLVRIAKVLGT+DLY YI+KY I+LDPRFNDI
Sbjct: 1118 WTCGVWAACLPA*SSGKSPFFHGHDNYDQLVRIAKVLGTDDLYGYIEKYQIDLDPRFNDI 1297
Query: 273 LGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTV 327
LGRHSRKRWERFVHSENQHL+SPEALDFLDKLLRYDH RLTAREAM+HPYF +
Sbjct: 1298 LGRHSRKRWERFVHSENQHLISPEALDFLDKLLRYDHNERLTAREAMDHPYFXPI 1462
>00638
Length = 1595
Score = 145 bits (365), Expect(2) = 4e-47, Method: Compositional matrix adjust.
Identities = 65/75 (86%), Positives = 71/75 (94%)
Frame = +2
Query: 85 LENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKAL 144
LENLRGG N+ITL IVKDPVSRTPAL+FEHVNNTDFKQLYQT TDYDIRFY+YE++KAL
Sbjct: 278 LENLRGGTNVITLLAIVKDPVSRTPALIFEHVNNTDFKQLYQTFTDYDIRFYLYELMKAL 457
Query: 145 DYCHSMGIMHRDVKP 159
D+CHSMGIMHRDVKP
Sbjct: 458 DFCHSMGIMHRDVKP 502
Score = 60.8 bits (146), Expect(2) = 4e-47, Method: Compositional matrix adjust.
Identities = 27/29 (93%), Positives = 29/29 (100%)
Frame = +1
Query: 35 NQDDYQLVRKLGRGKYSEVFEAINITNNE 63
NQDDYQ+VRKLGRGKYSEVFEAIN+TNNE
Sbjct: 127 NQDDYQIVRKLGRGKYSEVFEAINVTNNE 213
>12704
Length = 641
Score = 125 bits (315), Expect = 2e-29, Method: Compositional matrix adjust.
Identities = 56/63 (88%), Positives = 61/63 (96%)
Frame = +3
Query: 1 MSGPVPSRARVYTDVNTHRPREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINIT 60
++ P+PSRARVY DVNTH+PREYWDYESHVVEWGNQDDYQ+VRKLGRGKYSEVFEAINIT
Sbjct: 423 ITMPLPSRARVYADVNTHKPREYWDYESHVVEWGNQDDYQIVRKLGRGKYSEVFEAINIT 602
Query: 61 NNE 63
NNE
Sbjct: 603 NNE 611
>01060
Length = 1800
Score = 106 bits (264), Expect = 2e-23, Method: Compositional matrix adjust.
Identities = 66/242 (27%), Positives = 123/242 (50%), Gaps = 7/242 (2%)
Frame = +1
Query: 93 NIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQ------TLTDYDIRFYMYEILKALDY 146
NI+ L D++ + LVFE ++ D K L ++ Y+++I+ + +
Sbjct: 253 NIVCLEDVIME--DERLFLVFEFLS-MDLKMYIDKFPEGVVLDRRLVKSYVFQIVTGIXF 423
Query: 147 CHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAE-FYHPGQEYNVRVASRYFKGPELLVD 205
CH I+HRD+KP N++I+H +++ D+G+A F P + Y V + +++ PE+L+
Sbjct: 424 CHQRRIVHRDLKPQNLLINHTG-AIKIADFGMARTFALPVRAYTHEVVTLWYRAPEILMG 600
Query: 206 YQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIEL 265
Y +D+WS+G + A M+ R P F G DQL +I +++GT + + + +
Sbjct: 601 ASKYSTPVDVWSIGTIFADMLIRT-PIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKL-- 771
Query: 266 DPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFY 325
P FN + W+ SE + LD +++ L+ D R++ ++ ++H YF
Sbjct: 772 -PAFNGMF-----PLWKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYFL 933
Query: 326 TV 327
V
Sbjct: 934 NV 939
>14126
Length = 1265
Score = 103 bits (258), Expect = 8e-23, Method: Compositional matrix adjust.
Identities = 69/243 (28%), Positives = 122/243 (50%), Gaps = 10/243 (4%)
Frame = +3
Query: 92 PNIITLADIVKDPVSRTPA---LVFEHVNNTDFKQLYQT----LTDYDIRFYMYEILKAL 144
PN++ L D+ + ++ LVFE++ + L + L I+ M ++L +
Sbjct: 378 PNVVRLLDVSHNTITDREIRLNLVFEYIEHDLATYLAKCPSPGLGPDRIKDLMLQLLNGV 557
Query: 145 DYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLV 204
D+ HS I+HRD+KP N++I + R L+L D+GLA Y V + +++ PE+L+
Sbjct: 558 DFLHSNRIVHRDLKPQNLLISKDGR-LKLADFGLARIYSFHMALTTVVVTLWYRSPEVLM 734
Query: 205 DYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIE 264
+ Y S+D+WS GC+ A + F + F G +DQL +I +V+G D+ + ++
Sbjct: 735 QAE-YGTSVDIWSCGCIFAEL-FTRRALFKGSSEFDQLKKIFEVIGLPPAGDWPEGVSVH 908
Query: 265 LDPRFNDILGRHSRKRWERFVHSENQHLV---SPEALDFLDKLLRYDHQSRLTAREAMEH 321
R + Q LV P+A D ++K+L + R+++RE++ H
Sbjct: 909 -------------RNSFRPTPPVPLQTLVPEMDPQAKDLMEKMLVFKSGRRISSRESLLH 1049
Query: 322 PYF 324
PY
Sbjct: 1050PYL 1058
>01707
Length = 757
Score = 96.7 bits (239), Expect = 2e-20, Method: Compositional matrix adjust.
Identities = 63/223 (28%), Positives = 114/223 (51%), Gaps = 9/223 (4%)
Frame = +1
Query: 37 DDYQLVRKLGRGKYSEVFEAINITNNEXXXXXXXXXXX-----XXXXXXXXXXLENLRGG 91
+ Y+ + K+G G Y VF+ N ++ L+ L+
Sbjct: 64 EKYEKIGKIGEGSYGVVFKCRNKETSQLVAIKKFVESEDDPLIKKIAMREIRMLKQLKH- 240
Query: 92 PNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQ---TLTDYDIRFYMYEILKALDYCH 148
PN++ L ++ + + LVF++V++T +L + L + ++ +Y+ L A+++CH
Sbjct: 241 PNLVRLIEVFRR--KKRLHLVFDYVDHTLLNELDRYPRGLPEPMVKRIIYQTLLAVNFCH 414
Query: 149 SMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYH-PGQEYNVRVASRYFKGPELLVDYQ 207
+HRDVKP N++I + +++L D+G A PG EY VA+R+++ PELLV
Sbjct: 415 QYNTIHRDVKPENILITRQG-QVKLCDFGFARILTGPGDEYTDYVATRWYRAPELLVGDT 591
Query: 208 MYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLG 250
Y +D+W++GC+ A ++ + + G + DQL I K LG
Sbjct: 592 QYGPPVDVWAIGCVFAELL-TGQALWPGRSDVDQLHLIRKTLG 717
>04591
Length = 1117
Score = 90.5 bits (223), Expect = 9e-19, Method: Compositional matrix adjust.
Identities = 68/244 (27%), Positives = 117/244 (47%), Gaps = 10/244 (4%)
Frame = -2
Query: 93 NIITLADIV---KDPVSR---TPALVFEHVNNTDFKQLYQTL----TDYDIRFYMYEILK 142
N++ L +I P +R T L+FE+ + D L L + D + M ++L
Sbjct: 1038 NVVQLQEICHTQAGPYNRYKSTFYLIFEYCD-YDLAGLLNNLRVKFSLADKKNLMSQLLN 862
Query: 143 ALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPEL 202
L Y H+ I+HRD+K N+++ + L+L D+GL+ + + RV + +++ PEL
Sbjct: 861 GLFYIHTKQILHRDIKAANILLTRDG-VLKLADFGLSRPWVKSKRLTNRVVTLWYRPPEL 685
Query: 203 LVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYN 262
L+ + Y +DMW +GC++A M RK P G QL I + G+ + +
Sbjct: 684 LLGEREYGPEIDMWGVGCIMAEMWSRK-PLMQGRSEQHQLSLITDLCGSLNAEVWPGVTK 508
Query: 263 IELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHP 322
+EL + + G+ RK ER + L + E + +D LR D R+ A+ H
Sbjct: 507 LELYGKLDLPQGK-PRKVKERML----DLLKNKEGAELIDIFLRLDPGQRMNCDNALSHD 343
Query: 323 YFYT 326
+F+
Sbjct: 342 FFWV 331
>04138
Length = 800
Score = 86.7 bits (213), Expect = 1e-17, Method: Compositional matrix adjust.
Identities = 56/195 (28%), Positives = 101/195 (51%), Gaps = 6/195 (3%)
Frame = +1
Query: 144 LDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPG----QEYNVRVASRYFKG 199
L Y H I+HRD+K N++I + L+L D+GLA + Y RV + +++
Sbjct: 52 LYYIHRNKILHRDMKAANILITKQG-VLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRP 228
Query: 200 PELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLG--TEDLYDY 257
PELL+ + Y ++D W GC++A M + + P G +QL I ++ G T +++
Sbjct: 229 PELLLGDRNYSTAIDQWGAGCIMAEM-WTRNPIMQGTTEQNQLTLITQLCGSITPEVWPG 405
Query: 258 IDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTARE 317
+ + ++ + GR + R +RF + L P LD ++LL+ D R++A E
Sbjct: 406 VTQLSMYHQIKGALAAGRKNIIR-DRFA----RILKDPYGLDLFERLLKMDPSQRISADE 570
Query: 318 AMEHPYFYTVVKDQA 332
A+ H +F+ V+ ++
Sbjct: 571 ALNHDFFWVGVEPKS 615
>29581
Length = 1278
Score = 85.5 bits (210), Expect = 3e-17, Method: Compositional matrix adjust.
Identities = 69/255 (27%), Positives = 124/255 (48%), Gaps = 15/255 (5%)
Frame = -2
Query: 85 LENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTL----TDYDIRFYMYEI 140
L NLR NI+ L ++V + LV E+ D L + ++ ++ + ++
Sbjct: 1193 LLNLRHQ-NIVQLQEVVVGKSLDSLFLVMEYCEQ-DLASLLDNMPAPFSESQVKCIVLQL 1020
Query: 141 LKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFY-HPGQEYNVRVASRYFKG 199
LK L Y H I+HRD+K N+++ + +++ D+GLA Y P + +V + +++
Sbjct: 1019 LKGLRYLHEAFIIHRDLKVSNLLMT-DKGCVKIADFGLARNYGKPQKPMTPKVVTLWYRA 843
Query: 200 PELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYI- 258
PELL + + ++DMWS GC+L ++ K P G + Q+ I ++LGT + D I
Sbjct: 842 PELLFGSKTHSTAIDMWSAGCILGELLGHK-PLMPGRSDLQQIELIMELLGTPN--DTIW 672
Query: 259 ---------DKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDH 309
+++ ++ P +N++ RH+ W +S + L+ L Y
Sbjct: 671 PGFSQLPAFEQFTLKKQP-YNNL--RHTFP-W-----------LSESGIRLLNGLFMYHP 537
Query: 310 QSRLTAREAMEHPYF 324
Q R TA + +EH YF
Sbjct: 536 QKRATAEDCLEHSYF 492
>32000
Length = 644
Score = 85.1 bits (209), Expect = 4e-17, Method: Compositional matrix adjust.
Identities = 52/158 (32%), Positives = 81/158 (51%), Gaps = 3/158 (1%)
Frame = -1
Query: 170 KLRLIDWGLAE-FYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFR 228
K+++ D+GLA F P + Y V + +++ PE+L+ + Y +D+WSLGC+ M+ R
Sbjct: 575 KMKIADFGLARVFGLPVRTYTHEVITLWYRAPEILLGCRFYSVPVDIWSLGCIFVEMMTR 396
Query: 229 KEPFFHGHDNYDQLVRIAKVLGT--EDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVH 286
+ F G DQL RI + LGT E ++ + K P + + K E V
Sbjct: 395 RA-LFPGDSEIDQLYRIFRTLGTPDEKVWPGVSKL-----PDYKPTFPKWPLKNLETVVS 234
Query: 287 SENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYF 324
+S LD L ++L Y+ R++AR AM HPYF
Sbjct: 233 ------LSKVGLDLLKRMLTYNPNRRISARSAMRHPYF 138
>01756
Length = 1858
Score = 77.0 bits (188), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 66/269 (24%), Positives = 114/269 (42%), Gaps = 19/269 (7%)
Frame = -3
Query: 2 SGPVPSRARVYTDVNTHRPREYWDYESHVVEWGNQD-DYQLVRKLGRGKYSEVFEAINIT 60
S SR R D + P YE+ + ++D Y+ + K+G+G + EVF+A
Sbjct: 1835 STASASREREQKDSQRYSP-----YETLKFPFCDEDAKYEKLAKIGQGTFGEVFKARCKK 1671
Query: 61 NNEXXXXXXXXXXXXXXXXXXXXXLE----NLRGGPNIITLADIVKDPVSRTPA------ 110
+ E L N++ L +I +
Sbjct: 1670 TKQVVAMKKVLMDNEKEGFPITALREIKILQLLNHENVVDLIEICSTKATSANRYKSMFY 1491
Query: 111 LVFEHVNNTDFKQLYQTLTDY----DIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDH 166
LVFE + D L ++ +I+ M +++ L Y H I+HRD+K N++I
Sbjct: 1490 LVFEFCEH-DLAGLLSNMSVVFNLPEIKEVMKQLMNGLYYIHRNKILHRDMKAANILITK 1314
Query: 167 EHRKLRLIDWGLAEFYHPG----QEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCML 222
+ L+L D+GLA + Y RV + +++ PELL+ + Y ++D W GC++
Sbjct: 1313 QG-VLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRPPELLLGDRNYSTAIDQWGAGCIM 1137
Query: 223 ASMIFRKEPFFHGHDNYDQLVRIAKVLGT 251
A M + + P G +QL I ++ G+
Sbjct: 1136 AEM-WTRNPIMQGTTEQNQLTLITQLCGS 1053
>21079
Length = 878
Score = 76.3 bits (186), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 44/133 (33%), Positives = 74/133 (55%), Gaps = 5/133 (3%)
Frame = +1
Query: 92 PNIITLADIVKDPVSRTPALVFEHVNNTD-FKQLYQ---TLTDYDIRFYMYEILKALDYC 147
P ++ L D + P RT LV E V + F+++ + LT+ D ++ +I + Y
Sbjct: 4 PKLLMLWDAFEAP--RTMVLVMEFVGAGELFERVIRDDFVLTERDCVHFVRQICSGVGYM 177
Query: 148 HSMGIMHRDVKPHNVM-IDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDY 206
H+ I+H D+KP NV+ + ++++ID+GLA FY PG V + F PE +V+Y
Sbjct: 178 HTQSILHLDLKPENVLCVSDNSNQIKIIDFGLARFYKPGDSLQVLFGTPEFIAPE-VVNY 354
Query: 207 QMYDYSLDMWSLG 219
+++ DMWS+G
Sbjct: 355 DEINFTTDMWSIG 393
>15910
Length = 1361
Score = 70.1 bits (170), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 54/201 (26%), Positives = 91/201 (45%), Gaps = 2/201 (0%)
Frame = +2
Query: 129 TDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMID--HEHRKLRLIDWGLAEFYHPGQ 186
T+ D + +IL + Y H+ G++HRD+KP N++ + + KL+L D+GL+ P
Sbjct: 458 TEKDAARAISDILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLADFGLSRIIEPEV 637
Query: 187 EYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIA 246
+ + + + PE+L + Y S+DMWS+G + ++ EPFF ++
Sbjct: 638 QMSTVCGTPGYCAPEVLKGDK-YTPSVDMWSVGVIAYILLCGYEPFFAENEF-------- 790
Query: 247 KVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLR 306
++Y I K + D + W +S A D + KLL
Sbjct: 791 ------EMYRKIIKGEYKFDEEY-----------WSE---------ISENAKDVVRKLLV 892
Query: 307 YDHQSRLTAREAMEHPYFYTV 327
D + RLTA EA+ P+ V
Sbjct: 893 IDPKKRLTATEALRLPWVKGV 955
>23319
Length = 2235
Score = 68.6 bits (166), Expect = 4e-12, Method: Compositional matrix adjust.
Identities = 42/120 (35%), Positives = 60/120 (50%), Gaps = 2/120 (1%)
Frame = +3
Query: 207 QMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLG--TEDLYDYIDKYNIE 264
+MY S+DMWS GC+ A + P F G+D+ DQL RI K+LG TED + + +
Sbjct: 21 KMYSTSIDMWSAGCIFAELANAGRPLFPGNDDDDQLKRIFKLLGTPTEDQWPGMTQL--- 191
Query: 265 LDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYF 324
P + H W++ V N + D L LL R++A EA++HPYF
Sbjct: 192 --PNYRMFPMYHVTTTWQQVVPKLNS-----KGRDLLQCLLVCCPSDRMSADEALQHPYF 350
>26560
Length = 398
Score = 68.6 bits (166), Expect = 4e-12, Method: Compositional matrix adjust.
Identities = 36/106 (33%), Positives = 63/106 (59%)
Frame = -1
Query: 127 TLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQ 186
T+ ++RFY E++ L++ HS +++RD+KP N+++D E+ +R+ D GLA + +
Sbjct: 368 VFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLD-ENGHVRISDLGLACDFSKKR 192
Query: 187 EYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPF 232
+ V + + PE+L+ Q YD S D +S GCML ++ PF
Sbjct: 191 PH-ASVGTHGYMAPEVLMKGQSYDSSADWFSFGCMLYKLLKGHSPF 57
>00300
Length = 2318
Score = 62.4 bits (150), Expect = 3e-10, Method: Compositional matrix adjust.
Identities = 53/226 (23%), Positives = 104/226 (46%), Gaps = 18/226 (7%)
Frame = -1
Query: 39 YQLVRKLGRGKYSEVFEAINITNNEXXXXXXXXXXXXXXXXXXXXXLENLRGGPNIITLA 98
+Q K+G G++ +V+ A+N++ E L+ LR + I +
Sbjct: 1652 WQRGNKIGEGQFGKVYTAVNMSTGELMALKEMKFQPND--------LQQLREMCDEIKIF 1497
Query: 99 DIVKDP---------VSRTPALVF-EHVNNTDFKQLYQT-LTDYDIRFYMYEILKALDYC 147
+ ++ V + L+F E+ + ++ + L +Y IR Y EI+ A+++
Sbjct: 1496 EGIQHENLVKYYGVEVHKDEMLMFMEYCDTGTIEEAAKMGLPEYLIRRYTREIVLAVNHL 1317
Query: 148 HSMGIMHRDVKPHNVMIDHEHRKLRLIDWGL-----AEFYHPGQEYNVRVASRYFKGPEL 202
H I+HRD+K N+ + + ++L D+G + PG+ +N+ V + + PE+
Sbjct: 1316 HENSIVHRDIKGANIFLT-SNGHVKLGDFGCSVKLKSHTTMPGEFHNL-VGTTAYMAPEV 1143
Query: 203 LV--DYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIA 246
D Y + D+WSLGC++ M K P+ +NY + ++
Sbjct: 1142 FTQNDQGGYGRAADIWSLGCVVIEMATGKRPWHDLDNNYQIMYKVG 1005
>12721
Length = 821
Score = 61.6 bits (148), Expect = 5e-10, Method: Compositional matrix adjust.
Identities = 33/96 (34%), Positives = 57/96 (59%), Gaps = 1/96 (1%)
Frame = +1
Query: 140 ILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGL-AEFYHPGQEYNVRVASRYFK 198
LKAL + H+ G++HRD+K ++++ H+ K++L D+G A+ Q+ V + Y+
Sbjct: 400 CLKALAFLHANGVIHRDIKSDSILLSHDG-KVKLXDFGFCAQVTQDLQKRKSLVGTPYWM 576
Query: 199 GPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFH 234
PE++ Y +D+WSLG M+ MI + PFF+
Sbjct: 577 APEVISRLP-YGPEVDIWSLGIMVMEMIDAEPPFFN 681
>13212
Length = 1067
Score = 61.2 bits (147), Expect = 6e-10, Method: Compositional matrix adjust.
Identities = 53/208 (25%), Positives = 89/208 (42%), Gaps = 7/208 (3%)
Frame = -1
Query: 124 LYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVM--IDHEHRKLRLIDWGL-AE 180
L + +T+ I + +E+ ALD+ H ++HRD+K NV+ ID E ++L D+G+ A+
Sbjct: 1001 LEKPMTEAQICYVCHEMCMALDFLHRHHVIHRDIKAGNVLLTIDGE---VKLADFGVSAK 831
Query: 181 FYHPGQEYNVRVASRYFKGPELLVDYQM----YDYSLDMWSLGCMLASMIFRKEPFFHGH 236
Q+ + + + Y+ PE+++ + YD+ D+WSLG L + P H
Sbjct: 830 NTQTQQKRDTFIGTPYWMAPEVVLCETLKDTPYDFKADIWSLGVTLIEFAQIEPPNKEMH 651
Query: 237 DNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPE 296
L++I K +D K+W +
Sbjct: 650 -PMRVLIKIHK----------------------SDPPTLEKPKKWTKLFK---------- 570
Query: 297 ALDFLDKLLRYDHQSRLTAREAMEHPYF 324
DF+ K L D R TA E +EHP+
Sbjct: 569 --DFIAKCLVKDPNLRPTAAELLEHPFM 492
>12786
Length = 460
Score = 61.2 bits (147), Expect = 7e-10, Method: Compositional matrix adjust.
Identities = 43/143 (30%), Positives = 72/143 (50%), Gaps = 22/143 (15%)
Frame = -3
Query: 126 QTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPG 185
Q L I+FY E+L+A+ H+ G++H D+KP N M+ + L+LID+G+A
Sbjct: 425 QGLDRMMIKFYWREMLRAVKALHNEGVIHSDLKPANFMLVAGN--LKLIDFGIANTLQQD 252
Query: 186 QEY---NVRVASRYFKGPELLV-------DYQMYD--------YSL----DMWSLGCMLA 223
+ + RV + + PE ++ D M + Y + D+WSLGC+L
Sbjct: 251 KTSVLKDSRVGTPSYMSPEAIMAACDDSADDSMEEDGHRTKPKYKVGVRSDVWSLGCILY 72
Query: 224 SMIFRKEPFFHGHDNYDQLVRIA 246
+M++ + PF H +N +L I
Sbjct: 71 NMVYGRTPFQHIKNNMGKLQAIT 3
>01392
Length = 1806
Score = 60.5 bits (145), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 56/211 (26%), Positives = 88/211 (41%), Gaps = 12/211 (5%)
Frame = -1
Query: 128 LTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDH--EHRKLRLIDWGLAEFYH-- 183
L + + + I +ALD+ HS GI HRD+KP N++ +H + +++ D+ LA
Sbjct: 1800 LCEREASLVVRHIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGISCD 1621
Query: 184 ----PGQEYNVRVASRYFKGPEL----LVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHG 235
E V S + PE+ + D YD D+WSLG +L M+ PF
Sbjct: 1620 GDGTKTPELLTPVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILYIMLCGYPPF--- 1450
Query: 236 HDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSP 295
Y Q E +D D FN I H + S+ +S
Sbjct: 1449 ---YGQCGEDCGWNRGEACHDCQDML-------FNSIQDGHYK------FPSQEWTSISS 1318
Query: 296 EALDFLDKLLRYDHQSRLTAREAMEHPYFYT 326
A D + LL + + R +A + ++HP+ T
Sbjct: 1317 SAKDLIRHLLVREPRKRYSAADVLKHPWICT 1225
>30755
Length = 1137
Score = 60.5 bits (145), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 39/125 (31%), Positives = 66/125 (52%), Gaps = 2/125 (1%)
Frame = +2
Query: 126 QTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLA-EFYHP 184
+ T+ RFY EI+ AL Y HS GI++RD+K N+++D + +++ D+GL E
Sbjct: 17 RIFTEERTRFYGAEIISALGYLHSQGIIYRDLKLENLLLDKDGH-IKVADFGLCKEDITY 193
Query: 185 GQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFH-GHDNYDQLV 243
G+ + + PE+L D Y ++D W G ++ MI + PF++ HD L+
Sbjct: 194 GRTTKTFCGTPEYLAPEVLDDND-YGRAVDWWGTGVVMYEMICGRLPFYNRDHDVLFTLI 370
Query: 244 RIAKV 248
+ V
Sbjct: 371 LVEDV 385
>28638
Length = 1458
Score = 60.1 bits (144), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 28/77 (36%), Positives = 49/77 (63%), Gaps = 1/77 (1%)
Frame = -1
Query: 150 MGIMHRDVKPHNVMIDHEHRK-LRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQM 208
M I+H D+KP N+++ + R ++++D+G + GQ + SR+++ PE+L+
Sbjct: 774 MNIIHCDLKPENILLCNPKRSAIKIVDFGSS--CQLGQRIYQYIQSRFYRSPEVLLGVP- 604
Query: 209 YDYSLDMWSLGCMLASM 225
YD ++DMWSLGC+L M
Sbjct: 603 YDLAIDMWSLGCILVEM 553
Score = 32.7 bits (73), Expect = 0.25, Method: Compositional matrix adjust.
Identities = 32/141 (22%), Positives = 60/141 (42%), Gaps = 32/141 (22%)
Frame = -2
Query: 216 WSLGCMLASMIFRK----EPFFHGHDNYDQLVRIAKVLG------------TEDLYDYI- 258
W L C ++ + + P F G + +DQ+++I +VLG T +D +
Sbjct: 596 WPLTCGXWAVYWWRCTXGNPLFAGSNEFDQMMKIVEVLGVPPRHILDQAQKTRKYFDLLP 417
Query: 259 ------------DKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLR 306
KY + +++LG R + E H V+ + L F D +LR
Sbjct: 416 DGTYAPKKPRDNKKYKSPSSRKLHEVLGAEKGGPGGRRM-GEPGHTVA-DYLKFKDLILR 243
Query: 307 ---YDHQSRLTAREAMEHPYF 324
+D ++R++ A++H +F
Sbjct: 242 MLDFDPKTRISPYYALQHNFF 180
>01966
Length = 1735
Score = 59.7 bits (143), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 37/136 (27%), Positives = 72/136 (52%), Gaps = 7/136 (5%)
Frame = -1
Query: 93 NIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQ------TLTDYDIRFYMYEILKALDY 146
NI+ L D++ + LVFE ++ D K L ++ Y+++I+ +++
Sbjct: 1531 NIVCLEDVIME--DERLFLVFEFLS-MDLKMYIDKFPEGVVLDRRLVKSYVFQIVTGINF 1361
Query: 147 CHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAE-FYHPGQEYNVRVASRYFKGPELLVD 205
CH I+HRD+KP N++I+H +++ D+G+A F P + Y V + +++ PE+L+
Sbjct: 1360 CHQRRIVHRDLKPQNLLINHTG-AIKIADFGMARTFALPVRAYTHEVVTLWYRAPEILMG 1184
Query: 206 YQMYDYSLDMWSLGCM 221
Q + W+ G +
Sbjct: 1183 PQ---STPPXWTCGAL 1145
Score = 57.0 bits (136), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 32/119 (26%), Positives = 58/119 (48%)
Frame = -3
Query: 209 YDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPR 268
Y +D+WS+G + A M+ R P F G DQL +I +++GT + + + + P
Sbjct: 1175 YSTPVDVWSIGTIFADMLIRT-PIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKL---PA 1008
Query: 269 FNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTV 327
FN + W+ SE + LD +++ L+ D R++ ++ ++H YF V
Sbjct: 1007 FNGMF-----PLWKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYFLNV 846
>14420
Length = 528
Score = 57.4 bits (137), Expect = 9e-09, Method: Compositional matrix adjust.
Identities = 30/97 (30%), Positives = 55/97 (56%), Gaps = 1/97 (1%)
Frame = +2
Query: 139 EILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQ-EYNVRVASRYF 197
E L+AL++ H ++HRD+K N+++ + ++L D+G P Q + + V + Y+
Sbjct: 221 ECLQALEFLHENQVIHRDIKSDNILLGMDG-SVKLTDFGFCAQLSPEQSKRSTMVGTPYW 397
Query: 198 KGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFH 234
PE++ Q Y ++D+WSLG M MI + P+ +
Sbjct: 398 MAPEVVTRKQ-YGPTVDIWSLGVMCIEMIEGEPPYLN 505
>27405
Length = 532
Score = 57.0 bits (136), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 35/128 (27%), Positives = 67/128 (52%), Gaps = 3/128 (2%)
Frame = -3
Query: 90 GGPNIITLADIVKDPVSRTPALVFEHVNNTDFK---QLYQTLTDYDIRFYMYEILKALDY 146
G P I+ + + P + + +N D + T+ ++RFY E++ L++
Sbjct: 380 GSPFIVCMTYAFQTP--EKLCFILDLMNGGDLHYHLSQHGVFTEKEVRFYAAEVMLGLEH 207
Query: 147 CHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDY 206
HS +++RD+KP N+++D E+ +R+ D GLA + ++ + V + + PE+L+
Sbjct: 206 MHSRFVVYRDLKPANILLD-ENGHVRISDLGLACDFSK-KKPHASVGTHGYMAPEVLMKG 33
Query: 207 QMYDYSLD 214
Q YD S D
Sbjct: 32 QAYDSSAD 9
>18921
Length = 697
Score = 56.6 bits (135), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 34/110 (30%), Positives = 57/110 (51%), Gaps = 1/110 (0%)
Frame = +2
Query: 126 QTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLA-EFYHP 184
+TL + +I +Y LK L Y HS +HRD+K N+++++E +L D+G+A +
Sbjct: 302 KTLVEREIATILYYTLKGLXYLHSRRKIHRDIKAGNILLNNEGHA-KLADFGVAGQLTDT 478
Query: 185 GQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFH 234
+ N + + Y+ PE++ + YD D+WSLG M K P
Sbjct: 479 MAKRNTVIGTPYWMAPEVIQEIG-YDCVADIWSLGITALEMAEGKPPVME 625
>31885
Length = 529
Score = 55.5 bits (132), Expect = 4e-08, Method: Compositional matrix adjust.
Identities = 29/104 (27%), Positives = 55/104 (52%), Gaps = 4/104 (3%)
Frame = -2
Query: 133 IRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRV 192
++FY+ ++ LDY S I+HRD+KP N+++D E + D+ +A +
Sbjct: 366 VKFYLCQLALVLDYLRSQKIVHRDIKPDNILLD-EQGHCHVTDFNIATQLEDDELATSTS 190
Query: 193 ASRYFKGPEL----LVDYQMYDYSLDMWSLGCMLASMIFRKEPF 232
+R + PE+ + + + Y + +D WSLG L ++ ++ PF
Sbjct: 189 GTRPYMAPEVYGVAINERRGYGFPVDWWSLGVSLFELLKKRRPF 58
>03294
Length = 1684
Score = 55.1 bits (131), Expect = 4e-08, Method: Compositional matrix adjust.
Identities = 31/117 (26%), Positives = 58/117 (49%)
Frame = -1
Query: 211 YSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFN 270
+ +D+WS+G + A M+ R P F G DQL +I +++GT + + + + P FN
Sbjct: 1678 HPVDVWSIGTIFADMLIRT-PIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKL---PAFN 1511
Query: 271 DILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTV 327
+ W+ SE + LD +++ L+ D R++ ++ ++H YF V
Sbjct: 1510 GMF-----PLWKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYFLNV 1355
>19761
Length = 473
Score = 55.1 bits (131), Expect = 5e-08, Method: Compositional matrix adjust.
Identities = 38/125 (30%), Positives = 62/125 (49%), Gaps = 3/125 (2%)
Frame = -3
Query: 133 IRFYMYEILKALDYCHSMG--IMHRDVKPHNVMIDHEHRKLRLIDWGLA-EFYHPGQEYN 189
I ++ + AL+Y H+ I+HRD+KP N+ + E +RL D GLA + P
Sbjct: 417 IVCWLMQTASALNYMHTHTPVILHRDLKPQNIYVT-EKGDVRLGDLGLARKLTGPADFAT 241
Query: 190 VRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVL 249
+V + + PE+L Q Y+ D+WSLGC+ + +K G D + + +V+
Sbjct: 240 SQVGTIMYLSPEIL-SQQPYNSKSDIWSLGCVFYDITGKK-----GSDEMGVMFLLVQVM 79
Query: 250 GTEDL 254
G L
Sbjct: 78 GGRKL 64
>26711
Length = 405
Score = 55.1 bits (131), Expect = 5e-08, Method: Compositional matrix adjust.
Identities = 28/95 (29%), Positives = 53/95 (55%), Gaps = 1/95 (1%)
Frame = -2
Query: 139 EILKALDYCHSMGIMHRDVKPHNVMIDHEH-RKLRLIDWGLAEFYHPGQEYNVRVASRYF 197
++L L + H+ G++H D+KP N+++ + ++LID+GLA +P QE + + F
Sbjct: 392 QVLDILQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARKLYPPQETFLNHGTPGF 213
Query: 198 KGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPF 232
PE L D + + D+W +G + ++ + PF
Sbjct: 212 TSPEAL-DVKPISTASDVWGVGVLAYILLSGQSPF 111
>18484
Length = 635
Score = 54.7 bits (130), Expect = 6e-08, Method: Compositional matrix adjust.
Identities = 35/104 (33%), Positives = 55/104 (52%), Gaps = 6/104 (5%)
Frame = +1
Query: 135 FYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVAS 194
FY EI L + H GI++RD+K NVM+D E +++ D+G+ + G +
Sbjct: 55 FYAAEIAVGLFFLHDQGIIYRDLKLDNVMLDSEGH-IKIADFGMCKEGMTGD-----ATT 216
Query: 195 RYFKG------PELLVDYQMYDYSLDMWSLGCMLASMIFRKEPF 232
R F G PE+++ YQ Y S+D W+ G +L M+ + PF
Sbjct: 217 RTFCGTPDYIAPEIVL-YQPYSKSVDWWAYGVLLFEMLAGQPPF 345
>09606
Length = 1300
Score = 54.3 bits (129), Expect = 9e-08, Method: Compositional matrix adjust.
Identities = 54/222 (24%), Positives = 91/222 (40%), Gaps = 25/222 (11%)
Frame = -3
Query: 128 LTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAE------- 180
L + IR + ++ L Y HS+GI+ D++P V++D L+ D+GL++
Sbjct: 842 LPETSIRDFGIHLVTGLHYIHSLGILFHDLRPSKVLLD-TSGVLKFADFGLSKVEGENLE 666
Query: 181 -----FYHPGQEYNVRVASRYFK-----------GPELLVDYQMYDYSL--DMWSLGCML 222
F G ++N++ A K PE+ +Q + S+ D+W+LGC+
Sbjct: 665 ELFFKFAEAGDQWNIQSAEEMMKQVPTSGSPTYMAPEV---FQGAEPSIMSDLWALGCVF 495
Query: 223 ASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWE 282
M F P F G + YD + KVL E + + P
Sbjct: 494 YEM-FSGHPPFLG-ETYD--ITKDKVLNKEFPLPKVKGSRLSAKP--------------- 372
Query: 283 RFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYF 324
SPE L+ L+ LL+ D RL+ ++H ++
Sbjct: 371 -----------SPEFLNLLESLLQKDSTRRLSWASLVKHAFW 279
>19094
Length = 898
Score = 53.9 bits (128), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 32/101 (31%), Positives = 55/101 (54%), Gaps = 1/101 (0%)
Frame = +1
Query: 126 QTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLA-EFYHP 184
+TL + +I +Y LK L Y HS +HRD+K N+++++E +L D+G+A +
Sbjct: 43 KTLVEREIATILYYTLKGL*YLHSRRKIHRDIKAGNILLNNEGHA-KLADFGVAGQLTDT 219
Query: 185 GQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASM 225
+ N + + Y+ PE++ + YD D+WSLG M
Sbjct: 220 MAKRNTVIGTPYWMAPEVIQEIG-YDCVADIWSLGITALEM 339
>18287
Length = 678
Score = 53.9 bits (128), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 35/119 (29%), Positives = 63/119 (52%), Gaps = 3/119 (2%)
Frame = -3
Query: 209 YDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGT---EDLYDYIDKYNIEL 265
YDYS+D+WS+GC+ A ++ R+ F QL I ++GT ED+ +
Sbjct: 673 YDYSIDIWSVGCIFAELLSRRI-LFQAQGPVQQLDMIINLVGTPRPEDMERACEGAR--- 506
Query: 266 DPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYF 324
N IL + R++ +++ + H + EA+ L ++L + ++R++A EA+ HPY
Sbjct: 505 ----NHILNQPFRRQNLLTLYNLSPH-ATHEAVRLLTRMLILNPKNRISAEEALSHPYL 344
>13592
Length = 980
Score = 53.1 bits (126), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 63/296 (21%), Positives = 114/296 (38%), Gaps = 16/296 (5%)
Frame = +2
Query: 44 KLGRGKYSEVFEAINITNNEXXXXXXXXXX--XXXXXXXXXXXLENLRGGPNIITLADIV 101
K+G+G++ +V+ A+N E L+ L G I ++V
Sbjct: 5 KIGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETRALKNVAEELKILEG----IKHKNLV 172
Query: 102 K---DPVSRTPALVFEHVNNT----DFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMH 154
+ V R L+F + + +L L + R + ++L + H GI+H
Sbjct: 173 RYYGIEVHREELLIFMELCSEGTLESLVELTGGLPEALSRRFTAQLLSGVAELHKHGIVH 352
Query: 155 RDVKPHNVMIDHEHRKLRLIDWGLAEFYH-----PGQEYNVRVASRYFKGPELLVDYQMY 209
RD+K N+ + L+L D+G A PG E V ++ + PE+
Sbjct: 353 RDIKTANIFLVDGSNSLKLGDFGSAVKIQAHTTVPG-ELQGYVGTQAYMAPEVFTKTNSD 529
Query: 210 DYS--LDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDP 267
+ D+WS+GC++ M K P+ N+ + ++ +G + P
Sbjct: 530 GHGRLADIWSVGCVVVEMASGKRPWAQFDSNFQIMFKVG--MGEK--------------P 661
Query: 268 RFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPY 323
+ + L S E DF+D L++D + RL+A E +E +
Sbjct: 662 QAPESL--------------------SQEGHDFIDHCLQHDPKQRLSAIELLEQNF 769
>18401
Length = 463
Score = 50.4 bits (119), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 35/143 (24%), Positives = 75/143 (52%), Gaps = 10/143 (6%)
Frame = -3
Query: 192 VASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGT 251
V++R+++ PE++++ + + D+WS+GC++ ++ F HDN + L + ++LG+
Sbjct: 449 VSTRHYRAPEVILELG-WSHPCDVWSVGCIMFE-LYTGYTLFQTHDNKEHLAMMERILGS 276
Query: 252 EDLYDYIDK-------YNIELDPRFNDILGRHSRKRWE---RFVHSENQHLVSPEALDFL 301
Y K ++ LD + R+ R+ + R+V + ++ + D +
Sbjct: 275 LP-YRMAKKTKKQKYFHHGRLDVPERSSMARYVRENTKPLLRYV-KDRENKDHQQLFDLM 102
Query: 302 DKLLRYDHQSRLTAREAMEHPYF 324
KLL Y+ SR + +A++HP+F
Sbjct: 101 KKLLAYEASSRYSLLQALQHPFF 33
>03240
Length = 1683
Score = 49.7 bits (117), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 36/145 (24%), Positives = 57/145 (39%), Gaps = 45/145 (31%)
Frame = -3
Query: 134 RFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGL--------------- 178
RFY+ E+++A++ H MG +HRD+KP N++ID ++L D+GL
Sbjct: 982 RFYVAELVQAIESVHRMGFIHRDIKPDNILIDRNGH-IKLTDFGLCTGFRWTHNSKYYQR 806
Query: 179 ---------------------AEFYHPGQEYNVR---------VASRYFKGPELLVDYQM 208
E P + R V + + PE+L
Sbjct: 805 DGTHARQDSMEVKCQLDEQCQCEILKPLERRRKREQRCLAHSLVGTPNYIAPEVLSRLGG 626
Query: 209 YDYSLDMWSLGCMLASMIFRKEPFF 233
Y D WS+G +L M+ PF+
Sbjct: 625 YTSVCDWWSVGVILFEMLVGHPPFY 551
>21433
Length = 590
Score = 48.9 bits (115), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 43/172 (25%), Positives = 76/172 (44%)
Frame = +2
Query: 136 YMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASR 195
Y+Y++ AL+YCH ++HRD+KP N+++ L++ D+G + + P +
Sbjct: 182 YIYQLSSALEYCHYRKVIHRDIKPENLLLG-LKGDLKIADFGWS-VHAPSSRRTTMCGTL 355
Query: 196 YFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLY 255
+ PE +V+ + +D ++D+WSLG + Y+ LV GT L
Sbjct: 356 DYLPPE-MVEGKTHDENVDLWSLGVLC----------------YEFLV------GTPPLR 466
Query: 256 DYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRY 307
+ PR+ S + +V+P A D + KLLR+
Sbjct: 467 PSPTRPPTPASPRWT----------------SGSPSIVTPGARDLISKLLRH 574
>13078
Length = 773
Score = 48.5 bits (114), Expect = 5e-06, Method: Compositional matrix adjust.
Identities = 37/126 (29%), Positives = 61/126 (48%), Gaps = 14/126 (11%)
Frame = -1
Query: 213 LDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDK-------YNIEL 265
D+WS+GC++ ++ F HDN + L + ++LG+ Y K Y+ L
Sbjct: 734 CDVWSIGCIMFE-LYTGYTLFQTHDNKEHLAMMERILGSLP-YRMAKKTKKQKYFYHGRL 561
Query: 266 DPRFNDILGRHSR---KRWERFV----HSENQHLVSPEALDFLDKLLRYDHQSRLTAREA 318
D GR+ R K R+V + ++Q L D +DK+L Y+ +R + R+A
Sbjct: 560 DWDEKSSAGRYVRDNVKPLRRYVKDPDNEDHQQL-----FDLMDKMLSYEVSTRYSLRQA 396
Query: 319 MEHPYF 324
M HP+F
Sbjct: 395 MRHPFF 378
>31489
Length = 329
Score = 47.4 bits (111), Expect = 9e-06, Method: Compositional matrix adjust.
Identities = 27/77 (35%), Positives = 49/77 (63%), Gaps = 6/77 (7%)
Frame = +3
Query: 93 NIITLADIVKDPVS----RTPALVFEHVNNTDFKQLY--QTLTDYDIRFYMYEILKALDY 146
NII++ +I+K S + +VF+ + + + +Y Q LT+ IR+++Y+IL+ L Y
Sbjct: 33 NIISIREILKPKDSYHDFKDIHVVFDLMESDLHRIIYSDQPLTEEHIRYFLYQILRGLKY 212
Query: 147 CHSMGIMHRDVKPHNVM 163
HS ++HRD+KP N++
Sbjct: 213 IHSANVVHRDLKPSNLL 263
>13066
Length = 551
Score = 46.6 bits (109), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 27/90 (30%), Positives = 45/90 (50%), Gaps = 4/90 (4%)
Frame = +3
Query: 134 RFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGL--AEFYHPGQEYNVR 191
+ + Y++ AL+Y HS + HRD+K N+++ H ++L D+G A G++Y R
Sbjct: 285 KIWFYQMTTALNYLHSYDVAHRDLKCENILLS-SHFNVKLADFGFACACITESGEKYMSR 461
Query: 192 --VASRYFKGPELLVDYQMYDYSLDMWSLG 219
S + PE++ D WSLG
Sbjct: 462 TYCGSAAYAAPEIVYGAPYAPKVADAWSLG 551
>04852
Length = 1462
Score = 46.6 bits (109), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 28/90 (31%), Positives = 46/90 (51%), Gaps = 3/90 (3%)
Frame = +1
Query: 136 YMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASR 195
Y ++I + +++ S +HRD+ NV++ EH L++ D+GL+ G Y R R
Sbjct: 340 YAFQIARGMEFLASRKCIHRDLAARNVLVTEEH-VLKIADFGLS---RTGDYYKKRSGGR 507
Query: 196 Y---FKGPELLVDYQMYDYSLDMWSLGCML 222
+ PE L D + Y D+WS G +L
Sbjct: 508 LPVKWMAPEALFDMR-YTTKSDVWSFGVVL 594
>07940
Length = 1336
Score = 45.8 bits (107), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 29/104 (27%), Positives = 50/104 (48%), Gaps = 3/104 (2%)
Frame = -3
Query: 122 KQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEF 181
+ + + LT D+ Y Y++ + ++Y S +HRD+ NV++ E+ L++ D+GL
Sbjct: 374 QDMLKMLTPKDLISYAYQVARGMEYLASKQCIHRDLAARNVLVAEEY-VLKIADFGLTRN 198
Query: 182 YHPGQEYNVRVASRY---FKGPELLVDYQMYDYSLDMWSLGCML 222
Y R + PE L D + Y D+WS G +L
Sbjct: 197 LQQFDYYRKTTDGRLPVKWMAPEALFDRK-YTSKSDVWSYGVLL 69
>11185
Length = 473
Score = 44.7 bits (104), Expect = 7e-05, Method: Compositional matrix adjust.
Identities = 31/120 (25%), Positives = 55/120 (45%), Gaps = 25/120 (20%)
Frame = +1
Query: 132 DIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAE----------- 180
IR + ++ L Y HS+GI+ D++P V++D L+ D+GL++
Sbjct: 4 SIRDFGIHLVTGLHYIHSLGILFHDLRPSKVLLDTSGV-LKFADFGLSKVEGENLEELFF 180
Query: 181 -FYHPGQEYNVRVASRYFK-----------GPELLVDYQMYDYSL--DMWSLGCMLASMI 226
F G ++N++ A K PE+ +Q + S+ D+W+LGC+ M
Sbjct: 181 KFAEAGDQWNIQSAEEMMKQVPTSGSPTYMAPEV---FQGAEPSIMSDLWALGCVFYEMF 351
>00715
Length = 1788
Score = 43.9 bits (102), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 38/149 (25%), Positives = 63/149 (42%), Gaps = 27/149 (18%)
Frame = +1
Query: 111 LVFEHVNNTDFKQL---YQTLTDYDIRFYM-YEILKALDYCHSMGIMHRDVKPHNVMIDH 166
L E+V + + + +Q D +R + ++ + L Y HS+ I+H D+KP N ++
Sbjct: 166 LAMEYVGPLNLQTILNDHQQDIDSSMRLSLALQMARGLHYLHSINIVHLDLKPANCLLTR 345
Query: 167 EHRKLRLIDWGLAEFYHP-----------------------GQEYNVRVASRYFKGPELL 203
+ KLR+ D+G P G N + ++ PELL
Sbjct: 346 D-LKLRIADFGCCHQLTPTGLDMGEREGGMAGNELELTPVQGAWKNELAGTLAYRAPELL 522
Query: 204 VDYQMYDYSLDMWSLGCMLASMIFRKEPF 232
Q S D++SLG L M R+ P+
Sbjct: 523 KGLQPSVRS-DVYSLGITLWQMCTRQGPY 606
>17975
Length = 449
Score = 42.0 bits (97), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 16/44 (36%), Positives = 30/44 (68%)
Frame = +3
Query: 136 YMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLA 179
Y +I++A+ YCH + ++HRD+KP NV+ + ++L D+G +
Sbjct: 282 YFRQIVEAISYCHKLHVVHRDLKPENVVFFEKPGLVKLTDFGFS 413
>37602
Length = 804
Score = 40.8 bits (94), Expect = 9e-04, Method: Compositional matrix adjust.
Identities = 26/90 (28%), Positives = 40/90 (44%), Gaps = 3/90 (3%)
Frame = -1
Query: 111 LVFEHVNNTDFKQLYQT---LTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHE 167
+ E+ + +Y LT+ I F E LK L Y H G MHRD+K N+++ E
Sbjct: 288 IAMEYCGGGSMQDIYHVTGPLTEPQIAFVCRETLKGLHYLHRRGKMHRDIKGANILLTEE 109
Query: 168 HRKLRLIDWGLAEFYHPGQEYNVRVASRYF 197
D LA+F+ ++ V + F
Sbjct: 108 G------DVKLADFWRVSSNHSHNVQKKVF 37
>14116
Length = 1017
Score = 40.8 bits (94), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 27/105 (25%), Positives = 51/105 (48%), Gaps = 5/105 (4%)
Frame = -1
Query: 129 TDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLA-----EFYH 183
T D+ Y +I + +DY + +HRD+ N M+D E +++ D+GLA + Y+
Sbjct: 327 TIKDLIMYGVDIARGMDYLAGLKFVHRDLAARNCMLD-EDFHVKVADFGLARDIYEKEYY 151
Query: 184 PGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFR 228
+ ++ ++ L + YD D+WS G +L ++ R
Sbjct: 150 SSENKKAKLPVKWMALESL--EKGNYDSKTDVWSYGVVLWELLTR 22
>01718
Length = 959
Score = 40.0 bits (92), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 49/218 (22%), Positives = 90/218 (41%), Gaps = 9/218 (4%)
Frame = +3
Query: 20 PREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEXXXXXXXXXXXXXXXX 79
P+ H V + D + K+G G +SEVF+ + +
Sbjct: 96 PKSSCQALRHAVSALTRLDDFICEKIGAGFFSEVFKVTHRITGQVMALKMNTMTSNRHNM 275
Query: 80 XXXXXLENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTD---YDIRFY 136
L N NI+ + + AL E++ + + +QL + + + R
Sbjct: 276 LREVQLLNRLQHANILRFMGVCVHE-GQLHALT-EYIPSGNLEQLLEKKDEELPWTQRIQ 449
Query: 137 M-YEILKALDYCHSMGIMHRDVKPHNVMI---DHEHRKLRLIDWGLA-EFYHP-GQEYNV 190
+ + + LDY HS +HRD+ N++I D+ + D+GLA + P +E
Sbjct: 450 LTLGLARGLDYLHSTRFIHRDLTSKNILIRREDNHGYHAVIADFGLATKIPDPLDKEKLP 629
Query: 191 RVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFR 228
V S Y+ PE+L + Y+ D++S+G ++ + R
Sbjct: 630 TVGSPYWMAPEVL-NGHFYNERADLFSVGIIMCEITAR 740
>01106
Length = 878
Score = 38.9 bits (89), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 38/163 (23%), Positives = 68/163 (41%), Gaps = 18/163 (11%)
Frame = +3
Query: 20 PREYWDYESHVVEWGN--QDDYQLVRKLGRGKYSEV----------FEAINITNNEXXXX 67
PR+Y H V+ G+ Y ++RKLG G +S V F A+ + +
Sbjct: 261 PRDYCKGGYHPVKNGDLFNGRYHVIRKLGWGHFSTVWLCWDLTCKRFVALKVVKSAQHYT 440
Query: 68 XXXXXXXXXXXXXXXXXLENLRGGPNIITLADIVKDPVSRT-PALVFEHVNNTDFKQL-- 124
+ + + L D V+ T A+VFE + K +
Sbjct: 441 ETALDEVKLLKCVRESDVADPARAKCVQLLDDFKISGVNGTHVAMVFEVLGYNLLKLIIR 620
Query: 125 --YQTLTDYDIRFYMYEILKALDYCHSMG-IMHRDVKPHNVMI 164
YQ + ++++ + ++L+ L Y H+ I+H D+KP N++I
Sbjct: 621 SNYQGIPIHNVKLIIRQVLEGLSYMHAKCRIIHTDIKPENILI 749
>26009
Length = 886
Score = 38.9 bits (89), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 14/33 (42%), Positives = 24/33 (72%)
Frame = +3
Query: 132 DIRFYMYEILKALDYCHSMGIMHRDVKPHNVMI 164
+ + M +++ ALD+ HS ++HRD+KP NV+I
Sbjct: 714 EAKSVMKQLVSALDFMHSKQLVHRDIKPENVLI 812
>05084
Length = 1324
Score = 38.1 bits (87), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 26/92 (28%), Positives = 40/92 (43%), Gaps = 2/92 (2%)
Frame = +2
Query: 235 GHDNYDQLVRIAKVLGTEDLYDYIDKYNI-ELDPRFNDI-LGRHSRKRWERFVHSENQHL 292
G DQLV I KVLGT + I E++P +++ + W +
Sbjct: 8 GDSGVDQLVEIIKVLGTP------TREQIREMNPNYSEFKFPQIKAHPWTKVFRPRT--- 160
Query: 293 VSPEALDFLDKLLRYDHQSRLTAREAMEHPYF 324
PEA+ + +LL Y +R+ EA H +F
Sbjct: 161 -PPEAIQLVSRLLEYTPSARIQPMEACAHAFF 253
>00392
Length = 668
Score = 38.1 bits (87), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 25/93 (26%), Positives = 51/93 (54%), Gaps = 3/93 (3%)
Frame = +3
Query: 133 IRFYMYEILKALDYCHSMG--IMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNV 190
++ + ++LK L + H+ ++HRD+K N+ I +++ D GLA + +V
Sbjct: 252 LKNWCRQVLKGLYFLHTRTPPVIHRDLKCDNIFITGPTGSVKIGDLGLATLKNQSFAKSV 431
Query: 191 RVASRYFKGPELLVDYQMYDYSLDMWSLG-CML 222
+ + F PE+ ++ YD ++D+++ G CML
Sbjct: 432 -IGTPEFMAPEMYEEH--YDEAVDVYAFGMCML 521
>06358
Length = 1517
Score = 38.1 bits (87), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 48/176 (27%), Positives = 84/176 (47%), Gaps = 31/176 (17%)
Frame = +3
Query: 123 QLYQTLTDYDIRFYMYEILKALDYCHS-MGIMHRDVKPHNVMIDHEHRKLRLIDWGLA-- 179
Q YQ L D +I+ + ++ +AL + H+ +MHR+V P +M+ +L W LA
Sbjct: 339 QDYQ-LYDVEIKHGLLQVTEALGFLHNDAKMMHRNVCPEAIMLT------KLGSWKLAGY 497
Query: 180 EFY------------HPGQEYNVRVASRY-----FKGPELLVDYQMYDYSLDMWSLGCML 222
EF +P E+ +A F PE ++ Q S DM+SLG ++
Sbjct: 498 EFCVRSSDPQSTDPSYPFYEWRSDIAPVTQPHLDFMAPEYVLTMQCGTGS-DMFSLGLLV 674
Query: 223 ASMIFRKEPFFHGH-------DNYDQL--VRIAKVLGT--EDLYDYIDKYNIELDP 267
S+ + +P F + N ++L +R++ +LG EDL D++ K + ++P
Sbjct: 675 YSVFAKGKPLFECNGELSAFKSNAEELRHMRVS-LLGVVPEDLRDHV-KLLLNIEP 836
>21800
Length = 855
Score = 37.0 bits (84), Expect = 0.014, Method: Compositional matrix adjust.
Identities = 24/86 (27%), Positives = 45/86 (52%), Gaps = 10/86 (11%)
Frame = +2
Query: 110 ALVFEHVNNTDFKQL----YQTLTDYDIRFYMYEILKALDYCHS-MGIMHRDVKPHNVMI 164
+VFE + K + YQ + ++++ + ++L+ L+Y H+ I+H D+KP N++I
Sbjct: 557 CMVFEVLGYNLLKLIIRSNYQGIPVHNVKLIIRQVLEGLNYLHAKCNIIHTDIKPENILI 736
Query: 165 ---DHEHRKLRL--IDWGLAEFYHPG 185
D+ RKL + +W PG
Sbjct: 737 CVDDNYIRKLAVDAFEWQRLGLKLPG 814
>32359
Length = 928
Score = 28.5 bits (62), Expect(2) = 0.023, Method: Compositional matrix adjust.
Identities = 9/17 (52%), Positives = 14/17 (82%)
Frame = -3
Query: 151 GIMHRDVKPHNVMIDHE 167
G+ HRD+KP N+++D E
Sbjct: 65 GVCHRDIKPQNLLLDPE 15
Score = 26.6 bits (57), Expect(2) = 0.023, Method: Compositional matrix adjust.
Identities = 15/49 (30%), Positives = 26/49 (53%), Gaps = 6/49 (12%)
Frame = -1
Query: 111 LVFEHVNNTDFK------QLYQTLTDYDIRFYMYEILKALDYCHSMGIM 153
LV E+V T ++ + QT+ I+ YMY++ ++L Y HS +
Sbjct: 202 LVLEYVPETVYRVARHYSKSKQTIPILYIKLYMYQLFRSLAYIHSQACV 56
>27546
Length = 426
Score = 35.8 bits (81), Expect = 0.030, Method: Compositional matrix adjust.
Identities = 24/101 (23%), Positives = 47/101 (46%), Gaps = 11/101 (10%)
Frame = -1
Query: 92 PNIITLADIVKDPVSRTPAL-----------VFEHVNNTDFKQLYQTLTDYDIRFYMYEI 140
PNII + I++ R P + + H+ T + + + + +++
Sbjct: 300 PNIIQIHSILQ----RGPKIFIFMRYAEKGDMLSHIKKTG------PIDEAQTKVWFFQM 151
Query: 141 LKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEF 181
KAL Y HS I HRD+K N+++ + +++ D+G A +
Sbjct: 150 AKALQYLHSHDIAHRDLKCENILLS-KRLNVKIADFGFARY 31
>02638
Length = 1490
Score = 35.4 bits (80), Expect = 0.045, Method: Compositional matrix adjust.
Identities = 31/128 (24%), Positives = 52/128 (40%)
Frame = +1
Query: 197 FKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYD 256
F PE+L + Y + D+WS+GC++ M + P ++ HD + L I K+ +
Sbjct: 34 FMAPEVL-RGESYGRACDVWSVGCVMIEMCTCRPP-WNSHDISNHLALIFKIASS----- 192
Query: 257 YIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAR 316
+D I EN +SP D + + L D R +A+
Sbjct: 193 -VDPPPI-----------------------PEN---MSPPVRDLMLRCLEQDSDFRPSAK 291
Query: 317 EAMEHPYF 324
+ + HP F
Sbjct: 292 DLLMHPLF 315
>28157
Length = 400
Score = 34.7 bits (78), Expect = 0.060, Method: Compositional matrix adjust.
Identities = 29/105 (27%), Positives = 46/105 (43%), Gaps = 13/105 (12%)
Frame = +3
Query: 92 PNIITLADIVKD-PVSRTPALVFEHVNNTDFKQLYQTL---------TDYDIRFYMYEIL 141
PNI+ L +D PV LV E+ LY L T ++ +
Sbjct: 90 PNIVCLYGACRDHPV----CLVMEYAEGGS---LYNVLHGSGPQPQYTAAHAMNWLLQCA 248
Query: 142 KALDYCHSM---GIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYH 183
++Y H M ++HRD+KP N+++ KL++ D+G A H
Sbjct: 249 LGVEYLHGMKPKALIHRDLKPPNLLLIQCGTKLKICDFGTACDIH 383
>18481
Length = 437
Score = 34.7 bits (78), Expect = 0.062, Method: Compositional matrix adjust.
Identities = 19/51 (37%), Positives = 31/51 (60%), Gaps = 3/51 (5%)
Frame = -1
Query: 139 EILKALDYCHSMGIMHRDVKPHNVMID---HEHRKLRLIDWGLAEFYHPGQ 186
++L L++ H +HRD+KP N ++ H HR L +ID+GL++ Y Q
Sbjct: 173 QLLSRLEFIHQKCFIHRDLKPDNFLMGLGRHCHR-LYIIDFGLSKRYKDTQ 24
>29360
Length = 363
Score = 33.9 bits (76), Expect = 0.10, Method: Composition-based stats.
Identities = 21/66 (31%), Positives = 33/66 (50%), Gaps = 14/66 (21%)
Frame = +3
Query: 113 FEHVNNT--DFKQLYQTLTDY------------DIRFYMYEILKALDYCHSMGIMHRDVK 158
F+H N+T F+ L Q L D+ IR ++L AL +G++H D+K
Sbjct: 162 FQHKNHTCLVFEMLEQNLYDFLKQNKFQPLPLKYIRPITQQVLTALRKLKQLGLIHADLK 341
Query: 159 PHNVMI 164
P N+M+
Sbjct: 342 PENIML 359
>15931
Length = 447
Score = 33.5 bits (75), Expect = 0.14, Method: Compositional matrix adjust.
Identities = 12/29 (41%), Positives = 20/29 (68%)
Frame = +1
Query: 296 EALDFLDKLLRYDHQSRLTAREAMEHPYF 324
+ D +DK+L Y+ +R + R+AM HP+F
Sbjct: 70 QLFDLMDKMLSYEVSTRYSLRQAMRHPFF 156
>19301
Length = 712
Score = 33.1 bits (74), Expect = 0.18, Method: Compositional matrix adjust.
Identities = 28/105 (26%), Positives = 53/105 (50%), Gaps = 10/105 (9%)
Frame = +2
Query: 85 LENLR--GGPNIITLADIVKDPVSRTPA--LVFEHVNNTDFKQLYQTLTDYD------IR 134
+ NLR PNII+ K ++ P ++ E+ + QLY+ L D +
Sbjct: 422 IRNLRKLNHPNIISF----KGVCTQAPCYCIIMEYC---PYGQLYEVLRDGKEIPPALVL 580
Query: 135 FYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLA 179
+ +I ++Y HS I+HRD+K NV++ ++ +++ D+G +
Sbjct: 581 DWSKQIASGMNYLHSHKIIHRDLKSPNVLV-AKNDVVKISDFGTS 712
>26909
Length = 394
Score = 33.1 bits (74), Expect = 0.20, Method: Compositional matrix adjust.
Identities = 29/109 (26%), Positives = 43/109 (39%), Gaps = 10/109 (9%)
Frame = +2
Query: 226 IFRKEPFFHGHD---------NYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRH 276
+ EP FH ++DQL RI V+G D+ D + + R
Sbjct: 14 LLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFPQEKDWEDIRRMPEHQQLTKDFKRS 193
Query: 277 SRKRWERFVHSENQHL-VSPEALDFLDKLLRYDHQSRLTAREAMEHPYF 324
S + E + +A L KLL D R+T+ +AM+ PYF
Sbjct: 194 SYVNCNLMKYMEKHKVKADSKAFHLLQKLLTMDPVKRITSEQAMKDPYF 340
>29590
Length = 320
Score = 32.7 bits (73), Expect = 0.24, Method: Composition-based stats.
Identities = 18/58 (31%), Positives = 28/58 (48%)
Frame = +3
Query: 175 DWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPF 232
D G A + G++ + + + PE+L DY+ DMWSLG + M+ PF
Sbjct: 6 DLGFACLTNTGEDIRDIIGTPDYVAPEVL-DYEPLSIQTDMWSLGVLSYVMLTACSPF 176
>11801
Length = 743
Score = 32.7 bits (73), Expect = 0.24, Method: Compositional matrix adjust.
Identities = 23/82 (28%), Positives = 42/82 (51%), Gaps = 3/82 (3%)
Frame = -1
Query: 226 IFRKEPFFHGHDNYDQLVR---IAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWE 282
+ +K P YDQL R +AKV+ + D++ I+LDP+++ + ++S +
Sbjct: 272 LLKKFPVTSSSIPYDQLQRRCSVAKVVSETSCCKFGDQF-IKLDPQYDYRVAKYSYLQSY 96
Query: 283 RFVHSENQHLVSPEALDFLDKL 304
R+ QH+ +AL F D +
Sbjct: 95 RYFDDHKQHIR--QALMFNDTI 36
>14104
Length = 573
Score = 32.7 bits (73), Expect = 0.27, Method: Compositional matrix adjust.
Identities = 11/32 (34%), Positives = 19/32 (59%)
Frame = +1
Query: 293 VSPEALDFLDKLLRYDHQSRLTAREAMEHPYF 324
+P+A+ F+ L+ D RLT + ++HPY
Sbjct: 88 AAPQAMSFMQSCLKMDPAERLTCHQLLQHPYM 183
>12672
Length = 773
Score = 30.8 bits (68), Expect = 0.90, Method: Compositional matrix adjust.
Identities = 23/92 (25%), Positives = 43/92 (46%), Gaps = 7/92 (7%)
Frame = +3
Query: 142 KALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPG-----QEYNVRVASRY 196
+ Y + G +HRD+K N+++D E+ ++ D+ G Q +V + +
Sbjct: 24 SGIQYLNDNGHVHRDIKTANILLDSEYTA-KVGDFATVVSAPSGEGKTVQNASVVIGTAA 200
Query: 197 FKGPELLVDYQMYDYS--LDMWSLGCMLASMI 226
+ PE + +D S LD +S G +L +I
Sbjct: 201 YLAPEAI----HFDVSTKLDSYSFGVVLLEVI 284
>27274
Length = 396
Score = 30.4 bits (67), Expect = 1.2, Method: Compositional matrix adjust.
Identities = 30/126 (23%), Positives = 50/126 (39%)
Frame = -1
Query: 199 GPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYI 258
G ELL Q + ++DMWSLG +L ++ PF Q+ R +
Sbjct: 381 GAELLRG-QQHGPTVDMWSLGILLHELLSGHVPF-EPERGSRQMARNMMAV--------- 235
Query: 259 DKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREA 318
+ I+ SR + +S DFL +L++ + RLT+++A
Sbjct: 234 ----------YAQIIRGSSRDVCDGLA-------LSTHGADFLRRLVQLEDTKRLTSQQA 106
Query: 319 MEHPYF 324
HP+
Sbjct: 105 FSHPWI 88
>35032
Length = 465
Score = 30.0 bits (66), Expect = 1.5, Method: Compositional matrix adjust.
Identities = 12/27 (44%), Positives = 16/27 (59%)
Frame = +3
Query: 299 DFLDKLLRYDHQSRLTAREAMEHPYFY 325
D + +LL YD RLT A+ HP+ Y
Sbjct: 147 DLVKRLLNYDPSKRLTPXXALAHPFLY 227
>37063
Length = 455
Score = 30.0 bits (66), Expect = 1.6, Method: Compositional matrix adjust.
Identities = 25/79 (31%), Positives = 37/79 (46%), Gaps = 13/79 (16%)
Frame = -2
Query: 157 VKPHNVMIDH--EHRKLRLIDWGLAEFYHPGQ------EYNVRVASRYFKGPELLVDYQM 208
+KP N++ +H E L++ D+ LA + E V S + PE+ VD +
Sbjct: 454 LKPENILCEHLDEVVPLKICDFDLASGINCDGDGTKTPELLTPVGSAEYMAPEV-VDAWV 278
Query: 209 -----YDYSLDMWSLGCML 222
YD DMWSLG +L
Sbjct: 277 GESFSYDKRCDMWSLGIIL 221
>17932
Length = 597
Score = 30.0 bits (66), Expect = 1.8, Method: Compositional matrix adjust.
Identities = 17/35 (48%), Positives = 22/35 (62%)
Frame = -3
Query: 293 VSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTV 327
VS EA D + +LL D +SRL E +HP+F TV
Sbjct: 460 VSKEARDLISQLLS-DGKSRLGWPELQQHPFFKTV 359
>16350
Length = 1108
Score = 29.6 bits (65), Expect = 2.0, Method: Compositional matrix adjust.
Identities = 10/26 (38%), Positives = 18/26 (69%)
Frame = +3
Query: 299 DFLDKLLRYDHQSRLTAREAMEHPYF 324
DFL +L +D + R TA ++++HP+
Sbjct: 762 DFLAPMLEFDPEQRATAAQSLQHPWL 839
>20773
Length = 391
Score = 29.3 bits (64), Expect = 2.9, Method: Composition-based stats.
Identities = 16/50 (32%), Positives = 25/50 (50%)
Frame = -1
Query: 274 GRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPY 323
G H R+ F H+ +V+ + + +LL YD RLT A+ HP+
Sbjct: 370 GLHRRRSRPVFPHTT---VVTQHFYNLVQRLLTYDPSQRLTPDLALSHPF 230
>20513
Length = 405
Score = 28.9 bits (63), Expect = 3.5, Method: Compositional matrix adjust.
Identities = 10/26 (38%), Positives = 18/26 (69%)
Frame = -1
Query: 299 DFLDKLLRYDHQSRLTAREAMEHPYF 324
DFL +L +D + R TA ++++HP+
Sbjct: 282 DFLAPMLEFDPEQRATAAQSLQHPWL 205
>18663
Length = 600
Score = 28.9 bits (63), Expect = 4.0, Method: Compositional matrix adjust.
Identities = 13/34 (38%), Positives = 21/34 (61%)
Frame = +2
Query: 199 GPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPF 232
PE+L + Y +S+D W+LG +L M+ + PF
Sbjct: 32 APEILRG-EDYGFSVDWWALGVLLYEMLAGRSPF 130
>28419
Length = 687
Score = 28.1 bits (61), Expect = 6.1, Method: Compositional matrix adjust.
Identities = 22/77 (28%), Positives = 37/77 (48%), Gaps = 5/77 (6%)
Frame = +3
Query: 140 ILKALDYCHSMG----IMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASR 195
ILK L YC ++ ++ K N+ EH K++ + G + +R S+
Sbjct: 342 ILKRLRYCLNLSKPPSYLNTVRKL*NISYVREHDKVKALMLGFKLLVNSQCANALRHPSQ 521
Query: 196 YFKGPELL-VDYQMYDY 211
KGPEL+ D+Q Y++
Sbjct: 522 I*KGPELIPYDFQFYEF 572
>20152
Length = 445
Score = 27.7 bits (60), Expect = 8.3, Method: Compositional matrix adjust.
Identities = 12/39 (30%), Positives = 23/39 (58%)
Frame = +1
Query: 200 PELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDN 238
PE+L+ ++D+WSLG +L ++ + PF +D+
Sbjct: 1 PEILLGDSYDAPAVDVWSLGVILYMLVVGEAPFQEANDS 117
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000306043 | hsapiens_gene_ensembl | Cell division
control protein 2 homolog (EC 2.7.11.22) (EC 2.7.11.23) (p34 protein
kinase) (Cyclin-dependent kinase 1) (CDK1).
[Source:Uniprot/SWISSPROT;Acc:P06493]
(297 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
01060 402 e-112
14126 252 1e-67
01966 239 3e-65
01756 211 4e-55
32000 205 2e-53
01707 205 2e-53
29581 188 2e-48
04591 173 8e-44
04138 150 6e-37
24241 142 1e-34
03294 131 3e-31
20559 102 3e-28
18921 103 6e-23
13592 100 1e-21
23319 96 2e-20
06405 95 4e-20
00300 94 8e-20
12721 92 2e-19
15910 91 5e-19
09606 90 1e-18
01718 89 3e-18
17975 87 1e-17
14420 83 1e-16
28638 63 5e-16
19761 80 8e-16
03508 80 1e-15
03240 79 3e-15
04852 76 2e-14
19301 76 2e-14
21808 76 2e-14
12453 76 2e-14
11780 75 3e-14
13066 75 4e-14
21433 58 4e-12
01392 68 4e-12
31885 67 6e-12
18484 67 7e-12
27405 67 9e-12
27546 67 1e-11
18287 66 2e-11
00392 65 3e-11
26560 65 4e-11
30755 64 6e-11
19094 64 9e-11
14477 62 4e-10
26909 61 4e-10
13212 60 7e-10
14116 60 8e-10
17253 60 1e-09
07940 59 2e-09
31489 59 2e-09
26711 56 2e-08
18401 56 2e-08
28157 55 2e-08
32359 46 4e-08
22005 55 5e-08
00715 54 6e-08
21079 54 7e-08
11185 51 7e-07
16708 50 8e-07
13840 49 3e-06
07291 49 3e-06
01106 48 5e-06
16003 48 6e-06
20640 47 1e-05
13078 47 1e-05
36481 46 1e-05
12786 46 2e-05
18996 46 2e-05
11404 45 2e-05
06358 44 7e-05
05084 44 9e-05
26156 42 1e-04
16350 43 1e-04
17300 42 2e-04
31789 42 4e-04
37602 40 8e-04
02638 40 0.001
20152 40 0.001
25019 40 0.001
07836 40 0.002
00638 39 0.002
26009 38 0.004
12672 38 0.004
00394 38 0.006
21800 37 0.007
15549 36 0.015
20773 34 0.056
17644 34 0.087
18481 33 0.17
32357 33 0.17
38560 33 0.21
35032 32 0.30
15931 32 0.41
20513 30 1.3
29360 29 1.9
01007 29 3.0
21210 28 3.1
17516 28 5.7
13305 28 5.7
17806 27 8.4
26052 27 8.8
>01060
Length = 1800
Score = 402 bits (1032), Expect = e-112, Method: Compositional matrix adjust.
Identities = 176/295 (59%), Positives = 228/295 (77%)
Frame = +1
Query: 1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH 60
+ D T +KIGEGTYGVVYK RH+ TG+ +AMKKIRL E+GVPS+AIREI++L+ELRH
Sbjct: 70 LSDLTDFQKIGEGTYGVVYKCRHRATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELRH 249
Query: 61 PNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCH 120
NIV L+DV+M+D RL+L+FEFLSMDLK Y+D P G +D LVKSY++QI+ GI FCH
Sbjct: 250 TNIVCLEDVIMEDERLFLVFEFLSMDLKMYIDKFPEGVVLDRRLVKSYVFQIVTGIXFCH 429
Query: 121 SRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEAITLWYRSPEVLLGSAR 180
RR++HRDLKPQNLLI+ G IK+ADFG+AR F +P+R YTHE +TLWYR+PE+L+G+++
Sbjct: 430 QRRIVHRDLKPQNLLINHTGAIKIADFGMARTFALPVRAYTHEVVTLWYRAPEILMGASK 609
Query: 181 YSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNT 240
YSTPVD+WSIGTIFA++ + P+F GDSEIDQLF+IFR +GTP + WPE L +
Sbjct: 610 YSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKLPAFNGM 789
Query: 241 FPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLDNQIK 295
FP WK G L+ + +LD GLDL+ + L DPA+RIS K L H YF ++D +K
Sbjct: 790 FPLWKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYFLNVDTSVK 954
>14126
Length = 1265
Score = 252 bits (644), Expect = 1e-67, Method: Compositional matrix adjust.
Identities = 143/302 (47%), Positives = 189/302 (62%), Gaps = 11/302 (3%)
Frame = +3
Query: 2 EDYTKIEKIGEGTYGVVYKGRH-KTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELR- 59
+ Y ++ IG G YG VYK R + G+ VAMK+IRL + EEG+P AIREIS+LK+L
Sbjct: 189 QKYEEVAVIGNGAYGTVYKARDLRNQGEFVAMKRIRLNNTEEGMPMMAIREISMLKQLEQ 368
Query: 60 --HPNIVSLQDVLM-----QDSRLYLIFEFLSMDLKKYLDSIP-PGQYMDSSLVKSYLYQ 111
HPN+V L DV ++ RL L+FE++ DL YL P PG D +K + Q
Sbjct: 369 YEHPNVVRLLDVSHNTITDREIRLNLVFEYIEHDLATYLAKCPSPGLGPDR--IKDLMLQ 542
Query: 112 ILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEAITLWYRS 171
+L G+ F HS R++HRDLKPQNLLI G +KLADFGLAR + + + T +TLWYRS
Sbjct: 543 LLNGVDFLHSNRIVHRDLKPQNLLISKDGRLKLADFGLARIYSFHMALTT-VVVTLWYRS 719
Query: 172 PEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEV 231
PEVL+ A Y T VDIWS G IFAEL T++ LF G SE DQL +IF +G P WPE
Sbjct: 720 PEVLM-QAEYGTSVDIWSCGCIFAELFTRRALFKGSSEFDQLKKIFEVIGLPPAGDWPEG 896
Query: 232 ESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYF-NDL 290
S+ ++N+F P L + V +D DL+ KML++ +RIS + +L HPY +DL
Sbjct: 897 VSV--HRNSFRPTPPVPLQTLVPEMDPQAKDLMEKMLVFKSGRRISSRESLLHPYLRDDL 1070
Query: 291 DN 292
D+
Sbjct: 1071DS 1076
>01966
Length = 1735
Score = 239 bits (609), Expect(2) = 3e-65, Method: Compositional matrix adjust.
Identities = 115/223 (51%), Positives = 152/223 (68%), Gaps = 3/223 (1%)
Frame = -1
Query: 22 RHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQDVLMQDSRLYLIFE 81
RH+ TG+ +AMKKIRL E+GVPS+AIREI++L+ELRH NIV L+DV+M+D RL+L+FE
Sbjct: 1651 RHRATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTNIVCLEDVIMEDERLFLVFE 1472
Query: 82 FLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGT 141
FLSMDLK Y+D P G +D LVKSY++QI+ GI FCH RR++HRDLKPQNLLI+ G
Sbjct: 1471 FLSMDLKMYIDKFPEGVVLDRRLVKSYVFQIVTGINFCHQRRIVHRDLKPQNLLINHTGA 1292
Query: 142 IKLADFGLARAFGIPIRVYTHEAITLWYRSPEVLLGSARYSTPVDIWSIGTI--FAELAT 199
IK+ADFG+AR F +P+R YTHE +TLWYR+PE+L+G STP W+ G + + + +
Sbjct: 1291 IKIADFGMARTFALPVRAYTHEVVTLWYRAPEILMGPQ--STP-PXWTCGALEPSSPICS 1121
Query: 200 KKPL-FHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNTF 241
PL ++ R +L N P S Q F
Sbjct: 1120 SGPLSSRATPKLTSFLRYSGSLALQRNRRGPSFTSCQHSMACF 992
Score = 27.3 bits (59), Expect(2) = 3e-65, Method: Compositional matrix adjust.
Identities = 11/14 (78%), Positives = 13/14 (92%)
Frame = -2
Query: 6 KIEKIGEGTYGVVY 19
++ KIGEGTYGVVY
Sbjct: 1698 RLSKIGEGTYGVVY 1657
Score = 142 bits (357), Expect = 2e-34, Method: Compositional matrix adjust.
Identities = 62/119 (52%), Positives = 83/119 (69%)
Frame = -3
Query: 177 GSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQD 236
G+++YSTPVD+WSIGTIFA++ + P+F GDSEIDQLF+IFR +GTP + WPE L
Sbjct: 1187 GASKYSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKLPA 1008
Query: 237 YKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLDNQIK 295
+ FP WK G L+ + +LD GLDL+ + L DPA+RIS K L H YF ++D +K
Sbjct: 1007 FNGMFPLWKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYFLNVDTSVK 831
>01756
Length = 1858
Score = 211 bits (536), Expect = 4e-55, Method: Compositional matrix adjust.
Identities = 122/298 (40%), Positives = 177/298 (59%), Gaps = 14/298 (4%)
Frame = -3
Query: 4 YTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNI 63
Y K+ KIG+GT+G V+K R K T QVVAMKK+ +++E+EG P TA+REI +L+ L H N+
Sbjct: 1736 YEKLAKIGQGTFGEVFKARCKKTKQVVAMKKVLMDNEKEGFPITALREIKILQLLNHENV 1557
Query: 64 VSLQDVLMQD--------SRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQG 115
V L ++ S YL+FEF DL L ++ + +K + Q++ G
Sbjct: 1556 VDLIEICSTKATSANRYKSMFYLVFEFCEHDLAGLLSNM--SVVFNLPEIKEVMKQLMNG 1383
Query: 116 IVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRV---YTHEAITLWYRSP 172
+ + H ++LHRD+K N+LI +G +KLADFGLARAF + +R YT+ +TLWYR P
Sbjct: 1382 LYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRPP 1203
Query: 173 EVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVE 232
E+LLG YST +D W G I AE+ T+ P+ G +E +QL I + G+ EVWP VE
Sbjct: 1202 ELLLGDRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQNQLTLITQLCGSITPEVWPGVE 1023
Query: 233 SLQDYKN-TFPKWKPGSLASHVKNL--DENGLDLLSKMLIYDPAKRISGKMALNHPYF 287
L+ Y + P+ + ++ D LDLL K+L DP KR++ AL+H +F
Sbjct: 1022 RLELYNSLDLPQGNKRKVKERLRYYIKDAYALDLLDKLLALDPGKRVNSDEALSHDFF 849
>32000
Length = 644
Score = 205 bits (522), Expect = 2e-53, Method: Compositional matrix adjust.
Identities = 93/149 (62%), Positives = 116/149 (77%)
Frame = -1
Query: 142 IKLADFGLARAFGIPIRVYTHEAITLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKK 201
+K+ADFGLAR FG+P+R YTHE ITLWYR+PE+LLG YS PVDIWS+G IF E+ T++
Sbjct: 572 MKIADFGLARVFGLPVRTYTHEVITLWYRAPEILLGCRFYSVPVDIWSLGCIFVEMMTRR 393
Query: 202 PLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNTFPKWKPGSLASHVKNLDENGL 261
LF GDSEIDQL+RIFR LGTP+ +VWP V L DYK TFPKW +L + V +L + GL
Sbjct: 392 ALFPGDSEIDQLYRIFRTLGTPDEKVWPGVSKLPDYKPTFPKWPLKNLET-VVSLSKVGL 216
Query: 262 DLLSKMLIYDPAKRISGKMALNHPYFNDL 290
DLL +ML Y+P +RIS + A+ HPYFND+
Sbjct: 215 DLLKRMLTYNPNRRISARSAMRHPYFNDM 129
>01707
Length = 757
Score = 205 bits (521), Expect = 2e-53, Method: Compositional matrix adjust.
Identities = 104/222 (46%), Positives = 147/222 (66%), Gaps = 1/222 (0%)
Frame = +1
Query: 1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEG-VPSTAIREISLLKELR 59
ME Y KI KIGEG+YGVV+K R+K T Q+VA+KK +ESE++ + A+REI +LK+L+
Sbjct: 61 MEKYEKIGKIGEGSYGVVFKCRNKETSQLVAIKKF-VESEDDPLIKKIAMREIRMLKQLK 237
Query: 60 HPNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFC 119
HPN+V L +V + RL+L+F+++ L LD P G + +VK +YQ L + FC
Sbjct: 238 HPNLVRLIEVFRRKKRLHLVFDYVDHTLLNELDRYPRG--LPEPMVKRIIYQTLLAVNFC 411
Query: 120 HSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEAITLWYRSPEVLLGSA 179
H +HRD+KP+N+LI +G +KL DFG AR P YT T WYR+PE+L+G
Sbjct: 412 HQYNTIHRDVKPENILITRQGQVKLCDFGFARILTGPGDEYTDYVATRWYRAPELLVGDT 591
Query: 180 RYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALG 221
+Y PVD+W+IG +FAEL T + L+ G S++DQL I + LG
Sbjct: 592 QYGPPVDVWAIGCVFAELLTGQALWPGRSDVDQLHLIRKTLG 717
>29581
Length = 1278
Score = 188 bits (478), Expect = 2e-48, Method: Compositional matrix adjust.
Identities = 100/248 (40%), Positives = 145/248 (58%), Gaps = 3/248 (1%)
Frame = -2
Query: 45 PSTAIREISLLKELRHPNIVSLQDVLMQDS--RLYLIFEFLSMDLKKYLDSIPPGQYMDS 102
PS + L LRH NIV LQ+V++ S L+L+ E+ DL LD++P
Sbjct: 1223 PSVVCVRSTFLLNLRHQNIVQLQEVVVGKSLDSLFLVMEYCEQDLASLLDNMPAP--FSE 1050
Query: 103 SLVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTH 162
S VK + Q+L+G+ + H ++HRDLK NLL+ DKG +K+ADFGLAR +G P + T
Sbjct: 1049 SQVKCIVLQLLKGLRYLHEAFIIHRDLKVSNLLMTDKGCVKIADFGLARNYGKPQKPMTP 870
Query: 163 EAITLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGT 222
+ +TLWYR+PE+L GS +ST +D+WS G I EL KPL G S++ Q+ I LGT
Sbjct: 869 KVVTLWYRAPELLFGSKTHSTAIDMWSAGCILGELLGHKPLMPGRSDLQQIELIMELLGT 690
Query: 223 PNNEVWPEVESLQDYKNTFPKWKP-GSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMA 281
PN+ +WP L ++ K +P +L L E+G+ LL+ + +Y P KR + +
Sbjct: 689 PNDTIWPGFSQLPAFEQFTLKKQPYNNLRHTFPWLSESGIRLLNGLFMYHPQKRATAEDC 510
Query: 282 LNHPYFND 289
L H YF +
Sbjct: 509 LEHSYFKE 486
Score = 31.6 bits (70), Expect = 0.36, Method: Compositional matrix adjust.
Identities = 12/34 (35%), Positives = 23/34 (67%)
Frame = -1
Query: 28 QVVAMKKIRLESEEEGVPSTAIREISLLKELRHP 61
++VA+KK+R+ E G+P + +REI++ + P
Sbjct: 1275 EIVALKKMRMTGERYGIPISGLREINIFAQSATP 1174
>04591
Length = 1117
Score = 173 bits (438), Expect = 8e-44, Method: Compositional matrix adjust.
Identities = 99/260 (38%), Positives = 152/260 (58%), Gaps = 13/260 (5%)
Frame = -2
Query: 41 EEGVPSTAIREISLLKELRHPNIVSLQDVLMQD--------SRLYLIFEFLSMDLKKYLD 92
+EG P TA+REI +L++L H N+V LQ++ S YLIFE+ DL L+
Sbjct: 1101 KEGFPITALREIKILQQLEHENVVQLQEICHTQAGPYNRYKSTFYLIFEYCDYDLAGLLN 922
Query: 93 SIPPGQYMDSSLV--KSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLA 150
++ + SL K+ + Q+L G+ + H++++LHRD+K N+L+ G +KLADFGL+
Sbjct: 921 NL----RVKFSLADKKNLMSQLLNGLFYIHTKQILHRDIKAANILLTRDGVLKLADFGLS 754
Query: 151 RAFGIPIRVYTHEAITLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEI 210
R + + + T+ +TLWYR PE+LLG Y +D+W +G I AE+ ++KPL G SE
Sbjct: 753 RPW-VKSKRLTNRVVTLWYRPPELLLGEREYGPEIDMWGVGCIMAEMWSRKPLMQGRSEQ 577
Query: 211 DQLFRIFRALGTPNNEVWPEVESLQDY-KNTFPKWKPGSLASHVKNLDEN--GLDLLSKM 267
QL I G+ N EVWP V L+ Y K P+ KP + + +L +N G +L+
Sbjct: 576 HQLSLITDLCGSLNAEVWPGVTKLELYGKLDLPQGKPRKVKERMLDLLKNKEGAELIDIF 397
Query: 268 LIYDPAKRISGKMALNHPYF 287
L DP +R++ AL+H +F
Sbjct: 396 LRLDPGQRMNCDNALSHDFF 337
>04138
Length = 800
Score = 150 bits (379), Expect = 6e-37, Method: Compositional matrix adjust.
Identities = 79/185 (42%), Positives = 108/185 (58%), Gaps = 13/185 (7%)
Frame = +1
Query: 116 IVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRV---YTHEAITLWYRSP 172
+ + H ++LHRD+K N+LI +G +KLADFGLARAF + +R YT+ +TLWYR P
Sbjct: 52 LYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRPP 231
Query: 173 EVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVE 232
E+LLG YST +D W G I AE+ T+ P+ G +E +QL I + G+ EVWP V
Sbjct: 232 ELLLGDRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQNQLTLITQLCGSITPEVWPGVT 411
Query: 233 SLQDYKNTFPKWKPGSLASHVKNL----------DENGLDLLSKMLIYDPAKRISGKMAL 282
L Y G+LA+ KN+ D GLDL ++L DP++RIS AL
Sbjct: 412 QLSMYHQI-----KGALAAGRKNIIRDRFARILKDPYGLDLFERLLKMDPSQRISADEAL 576
Query: 283 NHPYF 287
NH +F
Sbjct: 577 NHDFF 591
>24241
Length = 413
Score = 142 bits (359), Expect = 1e-34, Method: Compositional matrix adjust.
Identities = 69/115 (60%), Positives = 88/115 (76%), Gaps = 1/115 (0%)
Frame = -2
Query: 6 KIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPN-IV 64
++ KIGEGTYGVVYK RH+ TG+ +AMKKIRL E+GVPS+AIREI++L+ELRH +V
Sbjct: 331 RLSKIGEGTYGVVYKCRHRATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTQXLV 152
Query: 65 SLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFC 119
L+DV+M+D RL+L+FEFLSMDLK Y+D P G +D LVK I+ GI FC
Sbjct: 151 CLEDVIMEDERLFLVFEFLSMDLKMYIDKFPEGVVLDRRLVK-----IVTGINFC 2
>03294
Length = 1684
Score = 131 bits (330), Expect = 3e-31, Method: Compositional matrix adjust.
Identities = 58/112 (51%), Positives = 76/112 (67%)
Frame = -1
Query: 184 PVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNTFPK 243
PVD+WSIGTIFA++ + P+F GDSEIDQLF+IFR +GTP + WPE L + FP
Sbjct: 1675 PVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKLPAFNGMFPL 1496
Query: 244 WKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLDNQIK 295
WK G L+ + +LD GLDL+ + L DPA+RIS K L H YF ++D +K
Sbjct: 1495 WKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYFLNVDTSVK 1340
>20559
Length = 430
Score = 102 bits (254), Expect(3) = 3e-28, Method: Compositional matrix adjust.
Identities = 45/80 (56%), Positives = 65/80 (81%)
Frame = -2
Query: 1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH 60
M+ Y K+EKIGEGTYG V+K +++ T ++VA+K++RL+ ++EGVPS+A+REI LLKEL+H
Sbjct: 378 MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKH 199
Query: 61 PNIVSLQDVLMQDSRLYLIF 80
NIV L DVL + +L L+F
Sbjct: 198 RNIVRLHDVLHSERKLTLVF 139
Score = 34.7 bits (78), Expect(3) = 3e-28, Method: Compositional matrix adjust.
Identities = 18/39 (46%), Positives = 27/39 (69%)
Frame = -3
Query: 80 FEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVF 118
FE+ DLKKY D+ G+ +D VKS+L+Q+L+G+ F
Sbjct: 140 FEYCDQDLKKYFDTC-NGE-IDPDTVKSFLHQLLRGLGF 30
Score = 25.0 bits (53), Expect(3) = 3e-28, Method: Compositional matrix adjust.
Identities = 9/14 (64%), Positives = 11/14 (78%)
Frame = -1
Query: 114 QGIVFCHSRRVLHR 127
+ +VFCHS VLHR
Sbjct: 43 EDLVFCHSNNVLHR 2
>18921
Length = 697
Score = 103 bits (258), Expect = 6e-23, Method: Compositional matrix adjust.
Identities = 60/194 (30%), Positives = 109/194 (56%)
Frame = +2
Query: 9 KIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQD 68
K+GEG+YG V+K HK TGQV+A+K++ ++++ + + I+EIS++++ IV
Sbjct: 50 KLGEGSYGSVFKSLHKETGQVLAIKQVPVDTDLQEI----IKEISIMQQCDSKYIVKYYG 217
Query: 69 VLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCHSRRVLHRD 128
+++ L+++ E+ + + ++ + + LY L+G+ + HSRR +HRD
Sbjct: 218 SYFKNTDLWIVMEYCGAGSVSDIMRLRNKTLVERE-IATILYYTLKGLXYLHSRRKIHRD 394
Query: 129 LKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEAITLWYRSPEVLLGSARYSTPVDIW 188
+K N+L++++G KLADFG+A + T ++ +PEV+ Y DIW
Sbjct: 395 IKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTPYWMAPEVIQ-EIGYDCVADIW 571
Query: 189 SIGTIFAELATKKP 202
S+G E+A KP
Sbjct: 572 SLGITALEMAEGKP 613
>13592
Length = 980
Score = 99.8 bits (247), Expect = 1e-21, Method: Compositional matrix adjust.
Identities = 72/282 (25%), Positives = 126/282 (44%), Gaps = 13/282 (4%)
Frame = +2
Query: 9 KIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQD 68
KIG+G +G VY + TG+++AMK+I ++ E E+ +L+ ++H N+V
Sbjct: 5 KIGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETRALKNVAEELKILEGIKHKNLVRYYG 184
Query: 69 VLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCHSRRVLHRD 128
+ + L + E S + L + G + +L + + Q+L G+ H ++HRD
Sbjct: 185 IEVHREELLIFMELCSEGTLESLVELTGG--LPEALSRRFTAQLLSGVAELHKHGIVHRD 358
Query: 129 LKPQNL-LIDDKGTIKLADFGLARAFGIPIRVYTHEAI---------TLWYRSPEVL--L 176
+K N+ L+D ++KL DFG A +++ H + T Y +PEV
Sbjct: 359 IKTANIFLVDGSNSLKLGDFGSA------VKIQAHTTVPGELQGYVGTQAYMAPEVFTKT 520
Query: 177 GSARYSTPVDIWSIGTIFAELAT-KKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQ 235
S + DIWS+G + E+A+ K+P ++ D F+I +G PE
Sbjct: 521 NSDGHGRLADIWSVGCVVVEMASGKRPW----AQFDSNFQIMFKVGMGEKPQAPE----- 673
Query: 236 DYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRIS 277
+L + G D + L +DP +R+S
Sbjct: 674 -------------------SLSQEGHDFIDHCLQHDPKQRLS 742
>23319
Length = 2235
Score = 95.9 bits (237), Expect = 2e-20, Method: Compositional matrix adjust.
Identities = 51/118 (43%), Positives = 71/118 (60%), Gaps = 2/118 (1%)
Frame = +3
Query: 181 YSTPVDIWSIGTIFAELATK-KPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKN 239
YST +D+WS G IFAELA +PLF G+ + DQL RIF+ LGTP + WP + L +Y+
Sbjct: 27 YSTSIDMWSAGCIFAELANAGRPLFPGNDDDDQLKRIFKLLGTPTEDQWPGMTQLPNYR- 203
Query: 240 TFPKWKPGSLASH-VKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLDNQIKK 296
FP + + V L+ G DLL +L+ P+ R+S AL HPYF DL +++
Sbjct: 204 MFPMYHVTTTWQQVVPKLNSKGRDLLQCLLVCCPSDRMSADEALQHPYFADLPPLVRQ 377
>06405
Length = 1965
Score = 94.7 bits (234), Expect = 4e-20, Method: Compositional matrix adjust.
Identities = 67/227 (29%), Positives = 119/227 (52%), Gaps = 10/227 (4%)
Frame = +1
Query: 9 KIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQD 68
++G G YG VY+ K ++VA+K ++ E+ + + E +++KE++HPN+V L
Sbjct: 280 RLGGGQYGDVYEAMWKRYNKIVAVKTLK---EDTMALNDFLEEAAIMKEMKHPNLVQLLG 450
Query: 69 VLMQDSRLYLIFEFLSM-DLKKYLDSIPPGQYMDSSLVKSYLY-QILQGIVFCHSRRVLH 126
V ++ Y++ EF+ +L YL S + ++L+ Y+ QI G+ + ++ +H
Sbjct: 451 VCTREPPFYIVTEFMPHGNLLDYLRSSTREENGPTALM--YMATQIASGMAYLETKNFIH 624
Query: 127 RDLKPQNLLIDDKGTIKLADFGLARAFGIPI-RVYTHEAITLWYRSPEVLLGSARYSTPV 185
RDL +N L+ D +K+ADFGLAR + + + +PE L + R+ST
Sbjct: 625 RDLAARNCLVADSNMVKVADFGLARLMKDDTYTAHIGAKFPIKWTAPEGLAFN-RFSTRS 801
Query: 186 DIWSIGTIFAELATKKPLFHGDSEIDQL-------FRIFRALGTPNN 225
DIW+ G + ELAT + E+ ++ +R+ R GTP +
Sbjct: 802 DIWAFGVLLWELATYGMSPYPGVELTEVYHLLERGYRMERPPGTPAD 942
>00300
Length = 2318
Score = 93.6 bits (231), Expect = 8e-20, Method: Compositional matrix adjust.
Identities = 65/289 (22%), Positives = 128/289 (44%), Gaps = 11/289 (3%)
Frame = -1
Query: 9 KIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQD 68
KIGEG +G VY + +TG+++A+K+++ + + EI + + ++H N+V
Sbjct: 1637 KIGEGQFGKVYTAVNMSTGELMALKEMKFQPNDLQQLREMCDEIKIFEGIQHENLVKYYG 1458
Query: 69 VLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCHSRRVLHRD 128
V + + + E+ + + +Y L++ Y +I+ + H ++HRD
Sbjct: 1457 VEVHKDEMLMFMEYCDTGTIEEAAKMGLPEY----LIRRYTREIVLAVNHLHENSIVHRD 1290
Query: 129 LKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEAI---------TLWYRSPEVLLGSA 179
+K N+ + G +KL DFG + +++ +H + T Y +PEV +
Sbjct: 1289 IKGANIFLTSNGHVKLGDFGCS------VKLKSHTTMPGEFHNLVGTTAYMAPEVFTQND 1128
Query: 180 R--YSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDY 237
+ Y DIWS+G + E+AT K +H ++D ++I +G + P+ S++
Sbjct: 1127 QGGYGRAADIWSLGCVVIEMATGKRPWH---DLDNNYQIMYKVGIGHKPAVPDSLSVE-- 963
Query: 238 KNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPY 286
G L ++ +DPA+R L+H +
Sbjct: 962 ----------------------GKHFLDLIMCHDPAQRALASQLLDHTF 882
>12721
Length = 821
Score = 92.4 bits (228), Expect = 2e-19, Method: Compositional matrix adjust.
Identities = 56/208 (26%), Positives = 102/208 (49%)
Frame = +1
Query: 9 KIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQD 68
KIGEG+ G+V + G+ +A+KK+ L ++ E+ ++++ HPNIV + +
Sbjct: 109 KIGEGSTGIVCIATSRD-GRQMAVKKMDLRKQQRR--ELLFNEVVVMRDYHHPNIVEMYN 279
Query: 69 VLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCHSRRVLHRD 128
+ + L+++ EF+ L I MD + + L+ + F H+ V+HRD
Sbjct: 280 SYLVNDELWVVMEFME---GGALTDIVTNNRMDEVQIATVCRACLKALAFLHANGVIHRD 450
Query: 129 LKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEAITLWYRSPEVLLGSARYSTPVDIW 188
+K ++L+ G +KL DFG ++ T ++ +PEV + Y VDIW
Sbjct: 451 IKSDSILLSHDGKVKLXDFGFCAQVTQDLQKRKSLVGTPYWMAPEV-ISRLPYGPEVDIW 627
Query: 189 SIGTIFAELATKKPLFHGDSEIDQLFRI 216
S+G + E+ +P F + + + RI
Sbjct: 628 SLGIMVMEMIDAEPPFFNEPPLQAMRRI 711
>15910
Length = 1361
Score = 90.9 bits (224), Expect = 5e-19, Method: Compositional matrix adjust.
Identities = 61/204 (29%), Positives = 97/204 (47%), Gaps = 3/204 (1%)
Frame = +2
Query: 97 GQYMDSSLVKSYLYQILQGIVFCHSRRVLHRDLKPQNLL---IDDKGTIKLADFGLARAF 153
GQY + ++ + IL G+ + H+ V+HRDLKP+NLL + D +KLADFGL+R
Sbjct: 449 GQYTEKDAARA-ISDILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLADFGLSRII 625
Query: 154 GIPIRVYTHEAITLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQL 213
+++ T T Y +PEVL G +Y+ VD+WS+G I L F ++E +
Sbjct: 626 EPEVQMSTVCG-TPGYCAPEVLKGD-KYTPSVDMWSVGVIAYILLCGYEPFFAENEFEMY 799
Query: 214 FRIFRALGTPNNEVWPEVESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPA 273
+I + + E W E+ EN D++ K+L+ DP
Sbjct: 800 RKIIKGEYKFDEEYWSEI-------------------------SENAKDVVRKLLVIDPK 904
Query: 274 KRISGKMALNHPYFNDLDNQIKKM 297
KR++ AL P+ + + M
Sbjct: 905 KRLTATEALRLPWVKGVATKTTNM 976
>09606
Length = 1300
Score = 90.1 bits (222), Expect = 1e-18, Method: Compositional matrix adjust.
Identities = 58/230 (25%), Positives = 105/230 (45%), Gaps = 22/230 (9%)
Frame = -3
Query: 1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH 60
ME++ E++G+G + ++YKGR K T VA+ I E + + ++ H
Sbjct: 1118 MENFVLYEELGKGEHSIIYKGRRKGTINFVAIHCIEKCKRPE-----VTNTVRMTHDISH 954
Query: 61 PNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCH 120
PN+V + + L+L+ E + D + ++ + ++ + ++ G+ + H
Sbjct: 953 PNVVQFHEWYETSNHLWLVVELCTGG--SLADILAQDHHLPETSIRDFGIHLVTGLHYIH 780
Query: 121 SRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIR---VYTHEAITLW--------- 168
S +L DL+P +L+D G +K ADFGL++ G + EA W
Sbjct: 779 SLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQWNIQSAEEMM 600
Query: 169 ----------YRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDS 208
Y +PEV G A S D+W++G +F E+ + P F G++
Sbjct: 599 KQVPTSGSPTYMAPEVFQG-AEPSIMSDLWALGCVFYEMFSGHPPFLGET 453
>01718
Length = 959
Score = 88.6 bits (218), Expect = 3e-18, Method: Compositional matrix adjust.
Identities = 64/206 (31%), Positives = 107/206 (51%), Gaps = 10/206 (4%)
Frame = +3
Query: 7 IEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSL 66
EKIG G + V+K H+ TGQV+A+K + S + +RE+ LL L+H NI+
Sbjct: 162 CEKIGAGFFSEVFKVTHRITGQVMALKMNTMTSNRHNM----LREVQLLNRLQHANILRF 329
Query: 67 QDVLMQDSRLYLIFEF-----LSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCHS 121
V + + +L+ + E+ L L+K + +P Q + +L + +G+ + HS
Sbjct: 330 MGVCVHEGQLHALTEYIPSGNLEQLLEKKDEELPWTQRIQLTL------GLARGLDYLHS 491
Query: 122 RRVLHRDLKPQNLLI---DDKG-TIKLADFGLARAFGIPIRVYTHEAI-TLWYRSPEVLL 176
R +HRDL +N+LI D+ G +ADFGLA P+ + + ++ +PEVL
Sbjct: 492 TRFIHRDLTSKNILIRREDNHGYHAVIADFGLATKIPDPLDKEKLPTVGSPYWMAPEVLN 671
Query: 177 GSARYSTPVDIWSIGTIFAELATKKP 202
G Y+ D++S+G I E+ + P
Sbjct: 672 GHF-YNERADLFSVGIIMCEITARIP 746
>17975
Length = 449
Score = 86.7 bits (213), Expect = 1e-17, Method: Compositional matrix adjust.
Identities = 51/138 (36%), Positives = 79/138 (57%), Gaps = 2/138 (1%)
Frame = +3
Query: 15 YGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQDVLMQDS 74
+ VV RH TG+ VA+K I +E S +E+ +K ++HPN+V L +V+ +
Sbjct: 6 FAVVKLARHVFTGEKVAVKVIDKTKLDEVSRSHLFQEVRCMKLVQHPNVVRLYEVIDTQT 185
Query: 75 RLYLIFEFL-SMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCHSRRVLHRDLKPQN 133
+LYLI E D+ Y+ G ++ L K Y QI++ I +CH V+HRDLKP+N
Sbjct: 186 KLYLILELGDGGDMYDYIMRHSGG--LEEKLAKRYFRQIVEAISYCHKLHVVHRDLKPEN 359
Query: 134 LLIDDK-GTIKLADFGLA 150
++ +K G +KL DFG +
Sbjct: 360 VVFFEKPGLVKLTDFGFS 413
>14420
Length = 528
Score = 83.2 bits (204), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 47/165 (28%), Positives = 84/165 (50%)
Frame = +2
Query: 49 IREISLLKELRHPNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSY 108
I EI +++E ++PNIV+ D + L+++ EFL+ L + MD + +
Sbjct: 44 INEILVMRENQNPNIVNYLDSYLVGEELWVVMEFLA---GGSLTDVVTETCMDEGQIAAV 214
Query: 109 LYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEAITLW 168
+ LQ + F H +V+HRD+K N+L+ G++KL DFG + T +
Sbjct: 215 CRECLQALEFLHENQVIHRDIKSDNILLGMDGSVKLTDFGFCAQLSPEQSKRSTMVGTPY 394
Query: 169 YRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQL 213
+ +PEV+ +Y VDIWS+G + E+ +P + ++ + L
Sbjct: 395 WMAPEVVT-RKQYGPTVDIWSLGVMCIEMIEGEPPYLNENPLRAL 526
>28638
Length = 1458
Score = 63.2 bits (152), Expect(2) = 5e-16, Method: Compositional matrix adjust.
Identities = 36/104 (34%), Positives = 58/104 (55%), Gaps = 4/104 (3%)
Frame = -1
Query: 103 SLVKSYLYQILQGIVFCHS--RRVLHRDLKPQNLLIDD--KGTIKLADFGLARAFGIPIR 158
+L + + Q+ ++F + ++H DLKP+N+L+ + + IK+ DFG + G I
Sbjct: 837 NLTRKFAQQLCTALLFLATPEMNIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIY 658
Query: 159 VYTHEAITLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKP 202
Y +YRSPEVLLG Y +D+WS+G I E+ T +P
Sbjct: 657 QYIQSR---FYRSPEVLLG-VPYDLAIDMWSLGCILVEMHTGEP 538
Score = 38.1 bits (87), Expect(2) = 5e-16, Method: Compositional matrix adjust.
Identities = 33/126 (26%), Positives = 50/126 (39%), Gaps = 34/126 (26%)
Frame = -2
Query: 202 PLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNTFP-------------KWK-PG 247
PLF G +E DQ+ +I LG P + + + + Y + P K+K P
Sbjct: 539 PLFAGSNEFDQMMKIVEVLGVPPRHILDQAQKTRKYFDLLPDGTYAPKKPRDNKKYKSPS 360
Query: 248 SLASHV-----------KNLDENG---------LDLLSKMLIYDPAKRISGKMALNHPYF 287
S H + + E G DL+ +ML +DP RIS AL H +F
Sbjct: 359 SRKLHEVLGAEKGGPGGRRMGEPGHTVADYLKFKDLILRMLDFDPKTRISPYYALQHNFF 180
Query: 288 NDLDNQ 293
++
Sbjct: 179 RKTSDE 162
>19761
Length = 473
Score = 80.5 bits (197), Expect = 8e-16, Method: Compositional matrix adjust.
Identities = 42/120 (35%), Positives = 67/120 (55%), Gaps = 2/120 (1%)
Frame = -3
Query: 104 LVKSYLYQILQGIVFCHSRR--VLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYT 161
L+ +L Q + + H+ +LHRDLKPQN+ + +KG ++L D GLAR P T
Sbjct: 420 LIVCWLMQTASALNYMHTHTPVILHRDLKPQNIYVTEKGDVRLGDLGLARKLTGPADFAT 241
Query: 162 HEAITLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALG 221
+ T+ Y SPE+ L Y++ DIWS+G +F ++ KK G E+ +F + + +G
Sbjct: 240 SQVGTIMYLSPEI-LSQQPYNSKSDIWSLGCVFYDITGKK----GSDEMGVMFLLVQVMG 76
>03508
Length = 1463
Score = 79.7 bits (195), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 60/205 (29%), Positives = 108/205 (52%), Gaps = 5/205 (2%)
Frame = +1
Query: 2 EDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH- 60
+DY + K+G G Y V++ + T + K ++ + REI +L+ LR
Sbjct: 589 DDYQIVRKLGRGKYSEVFEAINVTNNE-----KCVIKILKPVKKKKIKREIKILENLRGG 753
Query: 61 PNIVSLQDVLMQD-SRL-YLIFEFLS-MDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIV 117
N+++L ++ SR LIFE ++ D K+ + ++ YLY++++ +
Sbjct: 754 TNVITLLAIVKDPVSRTPALIFEHVNNTDFKQLYQTFTDYD------IRFYLYELMKALD 915
Query: 118 FCHSRRVLHRDLKPQNLLID-DKGTIKLADFGLARAFGIPIRVYTHEAITLWYRSPEVLL 176
FCHS ++HRD+KP N++ID + ++L D+GLA F P Y + +++ PE+LL
Sbjct: 916 FCHSMGIMHRDVKPHNVMIDHENKKLRLIDWGLAE-FYHPGMEYNVRVASRYFKGPELLL 1092
Query: 177 GSARYSTPVDIWSIGTIFAELATKK 201
Y +D+WS+G +FA + +K
Sbjct: 1093DYQMYDYSLDMWSLGCMFASMIFRK 1167
Score = 52.8 bits (125), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 35/114 (30%), Positives = 55/114 (48%), Gaps = 14/114 (12%)
Frame = +2
Query: 188 WSIGTIFAEL----ATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQ-DYKNTF- 241
W+ G A L + K P FHG DQL RI + LGT ++++ +E Q D F
Sbjct: 1118 WTCGVWAACLPA*SSGKSPFFHGHDNYDQLVRIAKVLGT--DDLYGYIEKYQIDLDPRFN 1291
Query: 242 --------PKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYF 287
+W+ + + + LD L K+L YD +R++ + A++HPYF
Sbjct: 1292 DILGRHSRKRWERFVHSENQHLISPEALDFLDKLLRYDHNERLTAREAMDHPYF 1453
>03240
Length = 1683
Score = 78.6 bits (192), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 66/271 (24%), Positives = 108/271 (39%), Gaps = 57/271 (21%)
Frame = -3
Query: 4 YTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNI 63
+ KI+ +G G +G V R TG + AMK +R+ +LK + ++
Sbjct: 1285 FEKIKTLGVGAFGEVSLCRKNDTGMLYAMK--------------TLRKSDVLKRNQVAHV 1148
Query: 64 VSLQDVLMQDSRLYLIFEFLSMDLKKYL----DSIPPGQYM---------DSSLVKSYLY 110
+ +D+L + +++ + S YL D +P G M D L + Y+
Sbjct: 1147 KAERDILAEADNEWVVKLYYSFQDHNYLYFVMDYVPGGDLMGLLIRMEILDEPLARFYVA 968
Query: 111 QILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFG---------------- 154
+++Q I H +HRD+KP N+LID G IKL DFGL F
Sbjct: 967 ELVQAIESVHRMGFIHRDIKPDNILIDRNGHIKLTDFGLCTGFRWTHNSKYYQRDGTHAR 788
Query: 155 -------------------IPI--------RVYTHEAI-TLWYRSPEVLLGSARYSTPVD 186
P+ R H + T Y +PEVL Y++ D
Sbjct: 787 QDSMEVKCQLDEQCQCEILKPLERRRKREQRCLAHSLVGTPNYIAPEVLSRLGGYTSVCD 608
Query: 187 IWSIGTIFAELATKKPLFHGDSEIDQLFRIF 217
WS+G I E+ P F+ ++ + +++
Sbjct: 607 WWSVGVILFEMLVGHPPFYANTPAETQYKVI 515
>04852
Length = 1462
Score = 76.3 bits (186), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 52/184 (28%), Positives = 89/184 (48%), Gaps = 33/184 (17%)
Frame = +1
Query: 47 TAIREISLLKELR----------HPNIVSLQDVLMQDSRLYLIFEFL-SMDLKKYLDSI- 94
TA+ E ++EL+ H NIV+ Q L++I EF + +L+ +L+S
Sbjct: 58 TAVEEQDFVQELQVMKAVKKMGSHINIVNFLGCCTQGGPLWVIVEFAKNGNLRDFLESCR 237
Query: 95 ---------------------PPGQYMDSSLVKSYLYQILQGIVFCHSRRVLHRDLKPQN 133
P G + + SY +QI +G+ F SR+ +HRDL +N
Sbjct: 238 DGINGYGKFVSPQDPGWYTKTPGGHVIRRKNLLSYAFQIARGMEFLASRKCIHRDLAARN 417
Query: 134 LLIDDKGTIKLADFGLARAFGIPIRVYTHEAITLWYRSPEVLLGSARYSTPVDIWSIGTI 193
+L+ ++ +K+ADFGL+R G + + + + + +PE L RY+T D+WS G +
Sbjct: 418 VLVTEEHVLKIADFGLSRT-GDYYKKRSGGRLPVKWMAPEALF-DMRYTTKSDVWSFGVV 591
Query: 194 FAEL 197
E+
Sbjct: 592 LWEI 603
>19301
Length = 712
Score = 75.9 bits (185), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 47/150 (31%), Positives = 78/150 (52%)
Frame = +2
Query: 1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH 60
E T +E +G G G V+ G K + VA+KK+R + T IR L++L H
Sbjct: 302 FESITDLEWLGSGAQGAVFLG--KLCAEEVAVKKVR------DIKETDIRN---LRKLNH 448
Query: 61 PNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCH 120
PNI+S + V Q +I E+ + + + G+ + +LV + QI G+ + H
Sbjct: 449 PNIISFKGVCTQAPCYCIIMEYCP--YGQLYEVLRDGKEIPPALVLDWSKQIASGMNYLH 622
Query: 121 SRRVLHRDLKPQNLLIDDKGTIKLADFGLA 150
S +++HRDLK N+L+ +K++DFG +
Sbjct: 623 SHKIIHRDLKSPNVLVAKNDVVKISDFGTS 712
>21808
Length = 1011
Score = 75.9 bits (185), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 48/161 (29%), Positives = 82/161 (50%), Gaps = 6/161 (3%)
Frame = +1
Query: 45 PSTAIREISLLKELRHPNIVSLQDVLMQDSRLYLIFEFL-SMDLKKYLDSIPPGQYMDSS 103
P + E ++K+LRHP ++ L V QD +++I E + + L ++L G+ +
Sbjct: 64 PKDFLAEAQIMKKLRHPKLIQLYAVCTQDDPIFIITELMKNGSLLEFLQG--KGRVLKLP 237
Query: 104 LVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHE 163
+ QI G+ + S+ +HRDL +N+L+ D T+K+ADFGLAR I+ +E
Sbjct: 238 ALIDIGAQIACGMAYLESQNYIHRDLAARNILVSDNNTVKIADFGLARV----IKEDEYE 405
Query: 164 A-----ITLWYRSPEVLLGSARYSTPVDIWSIGTIFAELAT 199
A + + +PE R++ D+WS G + E T
Sbjct: 406 ARVGARFPIKWTAPEA-ANYNRFTIKSDVWSFGILLTETVT 525
>12453
Length = 680
Score = 75.9 bits (185), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 38/102 (37%), Positives = 57/102 (55%), Gaps = 1/102 (0%)
Frame = +3
Query: 190 IGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKN-TFPKWKPGS 248
+G IF E+A +PLF G + D+L IF+ LGTP + P + D+ P ++ +
Sbjct: 6 VGCIFYEMACGRPLFPGSTVEDELHLIFKTLGTPTEDSLPSISRNPDFLALNLPHYQGEA 185
Query: 249 LASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDL 290
L + LD +GLDLL+K L Y+ R+S +L H +FN L
Sbjct: 186 LITIAPRLDSDGLDLLAKFLKYNAKIRVSAADSLKHSFFNSL 311
>11780
Length = 1713
Score = 75.1 bits (183), Expect = 3e-14, Method: Compositional matrix adjust.
Identities = 49/148 (33%), Positives = 88/148 (59%), Gaps = 1/148 (0%)
Frame = +3
Query: 8 EKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQ 67
E IG+G +G VYKG ++ GQ VA+K+++ + E + ++E S++ LRH N+V L
Sbjct: 615 EAIGKGDFGDVYKGMYR--GQPVAIKQLKDKDRGE---QSFLQEASVMTSLRHDNLVRLI 779
Query: 68 DVLMQDSRLYLIFEFLSM-DLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCHSRRVLH 126
V++ ++ ++L+ EF+ +L +YL S + ++ + + S+R++H
Sbjct: 780 GVVLGET-IFLVTEFMGKGNLVEYLRSRGRSVITKKDQI-NFATDTCAAMEYLESKRLVH 953
Query: 127 RDLKPQNLLIDDKGTIKLADFGLARAFG 154
RDL +N+L+ D G K++DFGLA+ FG
Sbjct: 954 RDLAARNVLVHDDGKAKVSDFGLAK-FG 1034
>13066
Length = 551
Score = 74.7 bits (182), Expect = 4e-14, Method: Compositional matrix adjust.
Identities = 52/187 (27%), Positives = 86/187 (45%), Gaps = 7/187 (3%)
Frame = +3
Query: 12 EGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQDVLM 71
GT+ Y K +++ +K ++ E+ P RE+ LL +L HP I+ + +L
Sbjct: 21 HGTFNDGYGRNIKLACKIIDKEKAPVDFVEKFFP----RELDLLTKLDHPYIIQIHSILQ 188
Query: 72 QDSRLYLIFEFLSM-DLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCHSRRVLHRDLK 130
+ + ++ F DL Y+ + ++ K + YQ+ + + HS V HRDLK
Sbjct: 189 RXPKNFIFMRFAERGDLLTYIQEV---GFVKEKQAKIWFYQMTTALNYLHSYDVAHRDLK 359
Query: 131 PQNLLIDDKGTIKLADFGLARAF------GIPIRVYTHEAITLWYRSPEVLLGSARYSTP 184
+N+L+ +KLADFG A A R Y A Y +PE++ G+
Sbjct: 360 CENILLSSHFNVKLADFGFACACITESGEKYMSRTYCGSAA---YAAPEIVYGAPYAPKV 530
Query: 185 VDIWSIG 191
D WS+G
Sbjct: 531 ADAWSLG 551
>21433
Length = 590
Score = 58.2 bits (139), Expect(2) = 4e-12, Method: Compositional matrix adjust.
Identities = 37/96 (38%), Positives = 55/96 (57%)
Frame = +2
Query: 107 SYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEAIT 166
Y+YQ+ + +CH R+V+HRD+KP+NLL+ KG +K+ADFG + P T T
Sbjct: 179 CYIYQLSSALEYCHYRKVIHRDIKPENLLLGLKGDLKIADFGW--SVHAPSSRRTTMCGT 352
Query: 167 LWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKP 202
L Y PE++ G + VD+WS+G + E P
Sbjct: 353 LDYLPPEMVEGKT-HDENVDLWSLGVLCYEFLVGTP 457
Score = 30.0 bits (66), Expect(2) = 4e-12, Method: Compositional matrix adjust.
Identities = 14/33 (42%), Positives = 19/33 (57%)
Frame = +3
Query: 50 REISLLKELRHPNIVSLQDVLMQDSRLYLIFEF 82
REI + LRH NI+ + +R+YLI EF
Sbjct: 15 REIEIQSHLRHDNILRMFGYFHDKTRVYLILEF 113
>01392
Length = 1806
Score = 68.2 bits (165), Expect = 4e-12, Method: Compositional matrix adjust.
Identities = 56/189 (29%), Positives = 85/189 (44%), Gaps = 12/189 (6%)
Frame = -1
Query: 111 QILQGIVFCHSRRVLHRDLKPQNLL---IDDKGTIKLADFGLARAFGIPIR-VYTHEAIT 166
I + + F HS+ + HRDLKP+N+L +DD +K+ DF LA T E +T
Sbjct: 1767 HIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGISCDGDGTKTPELLT 1588
Query: 167 ----LWYRSPEVLLG----SARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFR 218
Y +PEV+ S Y D+WS+G I + P F+G D +
Sbjct: 1587 PVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILYIMLCGYPPFYGQCGEDCGWNRGE 1408
Query: 219 ALGTPNNEVWPEVESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISG 278
A + ++ S+QD FP + S++S K DL+ +L+ +P KR S
Sbjct: 1407 ACHDCQDMLF---NSIQDGHYKFPSQEWTSISSSAK-------DLIRHLLVREPRKRYSA 1258
Query: 279 KMALNHPYF 287
L HP+
Sbjct: 1257 ADVLKHPWI 1231
>31885
Length = 529
Score = 67.4 bits (163), Expect = 6e-12, Method: Compositional matrix adjust.
Identities = 49/175 (28%), Positives = 88/175 (50%), Gaps = 7/175 (4%)
Frame = -2
Query: 52 ISLLKELRHPNIVSLQDVLMQDSRLYLIFE-FLSMDLKKYLDSIPPGQYMDSSLVKSYLY 110
+ +L L HP +V+L + L+++ + FL DL+ ++ + VK YL
Sbjct: 519 VDMLTRLDHPFLVNLWYAFQDEEDLFMVVDLFLGGDLRYHMQQEVSFR---EDCVKFYLC 349
Query: 111 QILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEAITLWYR 170
Q+ + + S++++HRD+KP N+L+D++G + DF +A + T + T Y
Sbjct: 348 QLALVLDYLRSQKIVHRDIKPDNILLDEQGHCHVTDFNIATQLE-DDELATSTSGTRPYM 172
Query: 171 SPEVL---LGSAR-YSTPVDIWSIGTIFAELATKKPLF--HGDSEIDQLFRIFRA 219
+PEV + R Y PVD WS+G EL K+ F H ++ + +++ A
Sbjct: 171 APEVYGVAINERRGYGFPVDWWSLGVSLFELLKKRRPFSVHSNTSLHEMWATMVA 7
>18484
Length = 635
Score = 67.4 bits (163), Expect = 7e-12, Method: Compositional matrix adjust.
Identities = 48/171 (28%), Positives = 81/171 (47%), Gaps = 1/171 (0%)
Frame = +1
Query: 108 YLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEAI-T 166
Y +I G+ F H + +++RDLK N+++D +G IK+ADFG+ + G+ T T
Sbjct: 58 YAAEIAVGLFFLHDQGIIYRDLKLDNVMLDSEGHIKIADFGMCKE-GMTGDATTRTFCGT 234
Query: 167 LWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNE 226
Y +PE++L YS VD W+ G + E+ +P F G+ E D+LF
Sbjct: 235 PDYIAPEIVLYQP-YSKSVDWWAYGVLLFEMLAGQPPFDGEDE-DELF------------ 372
Query: 227 VWPEVESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRIS 277
S+ D+ ++P K + + L +L+ +P KR+
Sbjct: 373 -----SSITDHNVSYP-----------KAMSREAVSLCKGLLMKNPTKRLG 477
>27405
Length = 532
Score = 67.0 bits (162), Expect = 9e-12, Method: Compositional matrix adjust.
Identities = 52/179 (29%), Positives = 91/179 (50%), Gaps = 7/179 (3%)
Frame = -3
Query: 15 YGVVYKGRHKTTGQVVAMKKI-RLESEEEGVPSTAIREISLLKELR----HPNIVSLQDV 69
+G VY R TG++ AMK + + + +G + A+ E +L + P IV +
Sbjct: 527 FGEVYGCRKADTGKMYAMKCLDKKRIKMKGGETLALNERIMLSLVSTGEGSPFIVCMTYA 348
Query: 70 LMQDSRLYLIFEFLSM-DLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCHSRRVLHRD 128
+L I + ++ DL +L G + + V+ Y +++ G+ HSR V++RD
Sbjct: 347 FQTPEKLCFILDLMNGGDLHYHLSQ--HGVFTEKE-VRFYAAEVMLGLEHMHSRFVVYRD 177
Query: 129 LKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEAI-TLWYRSPEVLLGSARYSTPVD 186
LKP N+L+D+ G ++++D GLA F + H ++ T Y +PEVL+ Y + D
Sbjct: 176 LKPANILLDENGHVRISDLGLACDFS---KKKPHASVGTHGYMAPEVLMKGQAYDSSAD 9
>27546
Length = 426
Score = 67.0 bits (162), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 30/103 (29%), Positives = 59/103 (57%), Gaps = 1/103 (0%)
Frame = -1
Query: 50 REISLLKELRHPNIVSLQDVLMQDSRLYLIFEFLSM-DLKKYLDSIPPGQYMDSSLVKSY 108
RE+ +L L HPNI+ + +L + ++++ + D+ ++ P +D + K +
Sbjct: 333 RELEILTRLDHPNIIQIHSILQRGPKIFIFMRYAEKGDMLSHIKKTGP---IDEAQTKVW 163
Query: 109 LYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLAR 151
+Q+ + + + HS + HRDLK +N+L+ + +K+ADFG AR
Sbjct: 162 FFQMAKALQYLHSHDIAHRDLKCENILLSKRLNVKIADFGFAR 34
>18287
Length = 678
Score = 65.9 bits (159), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 37/112 (33%), Positives = 60/112 (53%), Gaps = 3/112 (2%)
Frame = -3
Query: 181 YSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNE-VWPEVESLQDY-- 237
Y +DIWS+G IFAEL +++ LF + QL I +GTP E + E +++
Sbjct: 673 YDYSIDIWSVGCIFAELLSRRILFQAQGPVQQLDMIINLVGTPRPEDMERACEGARNHIL 494
Query: 238 KNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFND 289
F + +L + + + LL++MLI +P RIS + AL+HPY ++
Sbjct: 493 NQPFRRQNLLTLYNLSPHATHEAVRLLTRMLILNPKNRISAEEALSHPYLDE 338
>00392
Length = 668
Score = 65.1 bits (157), Expect = 3e-11, Method: Compositional matrix adjust.
Identities = 51/175 (29%), Positives = 89/175 (50%), Gaps = 10/175 (5%)
Frame = +3
Query: 51 EISLLKELRHPNIVSLQDVLMQDSR-----LYLIFEFL-SMDLKKYLDSIPPGQYMDSSL 104
E +LKEL+HPNIV D + + + L+ E + S LK YL + + +
Sbjct: 81 EAEMLKELQHPNIVRFFDYWEEHNHRNRKVIILVTELMTSGTLKTYLKRF---KKPNVKI 251
Query: 105 VKSYLYQILQGIVFCHSRR--VLHRDLKPQNLLIDD-KGTIKLADFGLARAFGIPIRVYT 161
+K++ Q+L+G+ F H+R V+HRDLK N+ I G++K+ D GLA + + +
Sbjct: 252 LKNWCRQVLKGLYFLHTRTPPVIHRDLKCDNIFITGPTGSVKIGDLGLA---TLKNQSFA 422
Query: 162 HEAI-TLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFR 215
I T + +PE+ Y VD+++ G E+A+ + + S Q+++
Sbjct: 423 KSVIGTPEFMAPEMY--EEHYDEAVDVYAFGMCMLEMASSEYPYSECSNAAQIYK 581
>26560
Length = 398
Score = 65.1 bits (157), Expect = 4e-11, Method: Compositional matrix adjust.
Identities = 37/114 (32%), Positives = 63/114 (55%), Gaps = 5/114 (4%)
Frame = -1
Query: 105 VKSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEA 164
V+ Y +++ G+ HSR V++RDLKP N+L+D+ G ++++D GLA F + H +
Sbjct: 350 VRFYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGLACDFS---KKRPHAS 180
Query: 165 I-TLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLF----HGDSEIDQL 213
+ T Y +PEVL+ Y + D +S G + +L F G + ID++
Sbjct: 179 VGTHGYMAPEVLMKGQSYDSSADWFSFGCMLYKLLKGHSPFRQHNQGQARIDRM 18
>30755
Length = 1137
Score = 63.9 bits (154), Expect = 6e-11, Method: Compositional matrix adjust.
Identities = 54/196 (27%), Positives = 89/196 (45%), Gaps = 9/196 (4%)
Frame = +2
Query: 105 VKSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLAR---AFGIPIRVYT 161
+ Y +I+ + + HS+ +++RDLK +NLL+D G IK+ADFGL + +G + +
Sbjct: 38 TRFYGAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCKEDITYGRTTKTFC 217
Query: 162 HEAITLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKK-PLFHGDSEIDQLFRIFRAL 220
T Y +PEV L Y VD W G + E+ + P ++ D ++ LF +
Sbjct: 218 G---TPEYLAPEV-LDDNDYGRAVDWWGTGVVMYEMICGRLPFYNRDHDV--LFTLIL-- 373
Query: 221 GTPNNEVWPEVESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISG-- 278
++D K FP +N+ + LLS +L DP R+ G
Sbjct: 374 -------------VEDVK--FP-----------RNITDEAKSLLSGLLAKDPRNRLGGGQ 475
Query: 279 ---KMALNHPYFNDLD 291
K HP+F ++
Sbjct: 476 DDVKEIQAHPFFASIN 523
>19094
Length = 898
Score = 63.5 bits (153), Expect = 9e-11, Method: Compositional matrix adjust.
Identities = 34/94 (36%), Positives = 54/94 (57%)
Frame = +1
Query: 105 VKSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEA 164
+ + LY L+G+ + HSRR +HRD+K N+L++++G KLADFG+A +
Sbjct: 64 IATILYYTLKGL*YLHSRRKIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVI 243
Query: 165 ITLWYRSPEVLLGSARYSTPVDIWSIGTIFAELA 198
T ++ +PEV+ Y DIWS+G E+A
Sbjct: 244 GTPYWMAPEVIQ-EIGYDCVADIWSLGITALEMA 342
>14477
Length = 493
Score = 61.6 bits (148), Expect = 4e-10, Method: Compositional matrix adjust.
Identities = 40/148 (27%), Positives = 80/148 (54%), Gaps = 3/148 (2%)
Frame = -1
Query: 9 KIGEGTYGVVYKGRHKTTGQV--VAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSL 66
K+G G +G V KG + + VA+K ++ + V S I+E ++K++ H +IV L
Sbjct: 469 KLGAGNFGSVMKGVCRLDDREIPVAIKVLKNADLDPSVQSELIKEAEVMKKMDHMHIVRL 290
Query: 67 QDVLMQDSRLYLIFEFLSMD-LKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCHSRRVL 125
L + + L+ E + L K+L P +++ + ++Q+ QG+ + + + +
Sbjct: 289 IG-LCEGETMMLVLELAKLGPLNKFL---PKNKHLPLWNILELMWQVSQGMEYLEANKFV 122
Query: 126 HRDLKPQNLLIDDKGTIKLADFGLARAF 153
HRDL +N+L+ D+ K++DFG+++
Sbjct: 121 HRDLAARNILLCDEHFAKISDFGMSKTL 38
>26909
Length = 394
Score = 61.2 bits (147), Expect = 4e-10, Method: Compositional matrix adjust.
Identities = 36/113 (31%), Positives = 52/113 (46%), Gaps = 18/113 (15%)
Frame = +2
Query: 193 IFAELATKKPLFHGDSEI---------DQLFRIFRALGTPNNEVWPEVESLQDYKNTFPK 243
IFAEL T +P+FH E DQL RIF +G P + W ++ + +++
Sbjct: 2 IFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFPQEKDWEDIRRMPEHQQLTKD 181
Query: 244 WKPGS---------LASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYF 287
+K S + H D LL K+L DP KRI+ + A+ PYF
Sbjct: 182 FKRSSYVNCNLMKYMEKHKVKADSKAFHLLQKLLTMDPVKRITSEQAMKDPYF 340
>13212
Length = 1067
Score = 60.5 bits (145), Expect = 7e-10, Method: Compositional matrix adjust.
Identities = 50/193 (25%), Positives = 80/193 (41%), Gaps = 5/193 (2%)
Frame = -1
Query: 100 MDSSLVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRV 159
M + + +++ + F H V+HRD+K N+L+ G +KLADFG++ +
Sbjct: 989 MTEAQICYVCHEMCMALDFLHRHHVIHRDIKAGNVLLTIDGEVKLADFGVSAKNTQTQQK 810
Query: 160 YTHEAITLWYRSPEVLLGSARYSTP----VDIWSIGTIFAELATKKPLFHGDSEIDQLFR 215
T ++ +PEV+L TP DIWS+G E A +P
Sbjct: 809 RDTFIGTPYWMAPEVVLCETLKDTPYDFKADIWSLGVTLIEFAQIEP------------- 669
Query: 216 IFRALGTPNNEVWPEVESLQDYKNTFPKW-KPGSLASHVKNLDENGLDLLSKMLIYDPAK 274
PN E+ P ++ +K+ P KP K D ++K L+ DP
Sbjct: 668 -------PNKEMHPMRVLIKIHKSDPPTLEKPKKWTKLFK-------DFIAKCLVKDPNL 531
Query: 275 RISGKMALNHPYF 287
R + L HP+
Sbjct: 530 RPTAAELLEHPFM 492
>14116
Length = 1017
Score = 60.5 bits (145), Expect = 8e-10, Method: Compositional matrix adjust.
Identities = 51/210 (24%), Positives = 97/210 (46%), Gaps = 14/210 (6%)
Frame = -1
Query: 5 TKIEKIGEGTYGVVYKGRHKTTGQ----VVAMKKIRLESEEEGVPSTAIREISLLKELRH 60
T E+IG+G +G V +G Q +VA+K + + E + ++E ++K+ H
Sbjct: 627 TMGEEIGKGNFGCVKRGFLTLPEQKGDILVAVKTLHNNNPREIELQSFLQEALIMKDFHH 448
Query: 61 PNIVSLQDVLMQ-DSRLYLIFEFLSM-DLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVF 118
N+++L + + D ++ F+ DL Y+ + ++ Y I +G+ +
Sbjct: 447 SNVLTLIGICLNLDDMPLVVLPFMKHGDLLTYIRDDQHQPTIKDLIM--YGVDIARGMDY 274
Query: 119 CHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEAITLWYRSPEV---- 174
+ +HRDL +N ++D+ +K+ADFGLAR +Y E + + ++
Sbjct: 273 LAGLKFVHRDLAARNCMLDEDFHVKVADFGLAR------DIYEKEYYSSENKKAKLPVKW 112
Query: 175 ----LLGSARYSTPVDIWSIGTIFAELATK 200
L Y + D+WS G + EL T+
Sbjct: 111 MALESLEKGNYDSKTDVWSYGVVLWELLTR 22
>17253
Length = 483
Score = 59.7 bits (143), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 36/134 (26%), Positives = 68/134 (50%), Gaps = 11/134 (8%)
Frame = -1
Query: 38 ESEEEGVPSTAIREISLLKEL-RHPNIVSLQDVLMQDSRLYLIFEFLSM-DLKKYLDSIP 95
E+ + S +RE+S++++L RHPN+VS ++ EF DL +L
Sbjct: 438 EAATDAEKSEFLRELSIMRKLPRHPNVVSFMGCCTMSDPALILMEFCCHGDLLSFLRKRR 259
Query: 96 PGQ--YMDSSLVK-------SYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLAD 146
P + ++ S+ S+ + +G+ + +++HRD+ +N+LI ++ K++D
Sbjct: 258 PDRTVFLTSTANDLTARDFFSFALHVARGMAHVANNKIVHRDVAARNVLISERNVCKVSD 79
Query: 147 FGLARAFGIPIRVY 160
FGL+R G VY
Sbjct: 78 FGLSRRVGDQNDVY 37
>07940
Length = 1336
Score = 59.3 bits (142), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 31/95 (32%), Positives = 55/95 (57%), Gaps = 2/95 (2%)
Frame = -3
Query: 107 SYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGI--PIRVYTHEA 164
SY YQ+ +G+ + S++ +HRDL +N+L+ ++ +K+ADFGL R R T
Sbjct: 335 SYAYQVARGMEYLASKQCIHRDLAARNVLVAEEYVLKIADFGLTRNLQQFDYYRKTTDGR 156
Query: 165 ITLWYRSPEVLLGSARYSTPVDIWSIGTIFAELAT 199
+ + + +PE L +Y++ D+WS G + E+ T
Sbjct: 155 LPVKWMAPEALF-DRKYTSKSDVWSYGVLLWEIFT 54
>31489
Length = 329
Score = 58.9 bits (141), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 33/90 (36%), Positives = 57/90 (63%), Gaps = 6/90 (6%)
Frame = +3
Query: 52 ISLLKELRHPNIVSLQDVLM-QDS-----RLYLIFEFLSMDLKKYLDSIPPGQYMDSSLV 105
I +LK +H NI+S++++L +DS ++++F+ + DL + + S P + +
Sbjct: 3 IKILKHFKHDNIISIREILKPKDSYHDFKDIHVVFDLMESDLHRIIYSDQP---LTEEHI 173
Query: 106 KSYLYQILQGIVFCHSRRVLHRDLKPQNLL 135
+ +LYQIL+G+ + HS V+HRDLKP NLL
Sbjct: 174 RYFLYQILRGLKYIHSANVVHRDLKPSNLL 263
>26711
Length = 405
Score = 55.8 bits (133), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 36/105 (34%), Positives = 54/105 (51%), Gaps = 2/105 (1%)
Frame = -2
Query: 111 QILQGIVFCHSRRVLHRDLKPQNLLI--DDKGTIKLADFGLARAFGIPIRVYTHEAITLW 168
Q+L + H++ V+H DLKP NLL+ D +++L DFGLAR P + + T
Sbjct: 392 QVLDILQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARKLYPPQETFLNHG-TPG 216
Query: 169 YRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQL 213
+ SPE L ST D+W +G + L + + F DS + L
Sbjct: 215 FTSPEA-LDVKPISTASDVWGVGVLAYILLSGQSPFQADSATESL 84
>18401
Length = 463
Score = 55.8 bits (133), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 49/145 (33%), Positives = 67/145 (46%), Gaps = 22/145 (15%)
Frame = -3
Query: 166 TLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALG---- 221
T YR+PEV+L +S P D+WS+G I EL T LF + L + R LG
Sbjct: 443 TRHYRAPEVILELG-WSHPCDVWSVGCIMFELYTGYTLFQTHDNKEHLAMMERILGSLPY 267
Query: 222 -----TPNNEVW-------PEVESLQDY--KNTFPKWKPGSLASHVK---NLDENGL-DL 263
T + + PE S+ Y +NT P L +VK N D L DL
Sbjct: 266 RMAKKTKKQKYFHHGRLDVPERSSMARYVRENTKP------LLRYVKDRENKDHQQLFDL 105
Query: 264 LSKMLIYDPAKRISGKMALNHPYFN 288
+ K+L Y+ + R S AL HP+F+
Sbjct: 104 MKKLLAYEASSRYSLLQALQHPFFS 30
>28157
Length = 400
Score = 55.5 bits (132), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 42/126 (33%), Positives = 66/126 (52%), Gaps = 5/126 (3%)
Frame = +3
Query: 30 VAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQDVLMQDSRLYLIFEFL-SMDLK 88
VA+K R+ESE+E + ++E+ L + HPNIV L +D + L+ E+ L
Sbjct: 9 VAVK--RIESEQE--KKSFMQELKQLSRVSHPNIVCLYGAC-RDHPVCLVMEYAEGGSLY 173
Query: 89 KYLDSIPPGQYMDSSLVKSYLYQILQGIVFCHS---RRVLHRDLKPQNLLIDDKGT-IKL 144
L P ++ ++L Q G+ + H + ++HRDLKP NLL+ GT +K+
Sbjct: 174 NVLHGSGPQPQYTAAHAMNWLLQCALGVEYLHGMKPKALIHRDLKPPNLLLIQCGTKLKI 353
Query: 145 ADFGLA 150
DFG A
Sbjct: 354 CDFGTA 371
>32359
Length = 928
Score = 45.8 bits (107), Expect(2) = 4e-08, Method: Compositional matrix adjust.
Identities = 32/129 (24%), Positives = 63/129 (48%), Gaps = 7/129 (5%)
Frame = -1
Query: 4 YTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNI 63
YT + IG G++GVVY+ + T ++VA+KK+ + + RE+ ++++L H NI
Sbjct: 424 YTDAKVIGNGSFGVVYQAKLVDTSELVAIKKVLQDKRFKN------RELQIMRKLEHQNI 263
Query: 64 VSLQDVLMQDSR------LYLIFEFLSMDLKKYLDSIPPG-QYMDSSLVKSYLYQILQGI 116
V L+ L L+ E++ + + Q + +K Y+YQ+ + +
Sbjct: 262 VKLKFFFYSSGEKKDEVFLNLVLEYVPETVYRVARHYSKSKQTIPILYIKLYMYQLFRSL 83
Query: 117 VFCHSRRVL 125
+ HS+ +
Sbjct: 82 AYIHSQACV 56
Score = 28.5 bits (62), Expect(2) = 4e-08, Method: Compositional matrix adjust.
Identities = 11/14 (78%), Positives = 13/14 (92%)
Frame = -3
Query: 124 VLHRDLKPQNLLID 137
V HRD+KPQNLL+D
Sbjct: 62 VCHRDIKPQNLLLD 21
>22005
Length = 873
Score = 54.7 bits (130), Expect = 5e-08, Method: Compositional matrix adjust.
Identities = 65/242 (26%), Positives = 96/242 (39%), Gaps = 54/242 (22%)
Frame = +1
Query: 10 IGEGTYGVVYK----GRHKTTGQVVAMK------KIRLESEEEGVPSTAIREISLLKELR 59
IG+G +G V K G G+++ K K+ E E + S RE SL+ +
Sbjct: 7 IGQGAFGRVSKLKFLGLASLVGELIPEKRP*LL*KMLKEDASEDLQSDFEREASLMADFD 186
Query: 60 HPNIVSLQDVLMQDSRLYLIFEFLSM-DLKKYLDSIPPGQY------------------- 99
HPNIV L V + L+FEF+S DL +L P Y
Sbjct: 187 HPNIVKLLGVCAIGKPMCLLFEFMSKGDLNDFLRLCSPENYNLPVSRSQNLVVDLEDGLR 366
Query: 100 ----------------MDSS---LVKSYLY---QILQGIVFCHSRRVLHRDLKPQNLLID 137
D S K LY QI G+ + + +HRDL + +
Sbjct: 367 VEVEAEECEKDTQSEDRDCSGMLXTKDQLYISQQISAGMAYLAQKDYVHRDLATRTVXS- 543
Query: 138 DKGTIKLADFGLARAFGIP--IRVYTHEAITLWYRSPEVLLGSARYSTPVDIWSIGTIFA 195
++DFGLAR+ R +AI + + E +L S ++ST D+WS G +
Sbjct: 544 RTT*S*ISDFGLARSVHSVDYYRGSEQDAIPIRWMPLEAILYS-KFSTQSDVWSFGVVLW 720
Query: 196 EL 197
E+
Sbjct: 721 EI 726
>00715
Length = 1788
Score = 54.3 bits (129), Expect = 6e-08, Method: Compositional matrix adjust.
Identities = 49/175 (28%), Positives = 88/175 (50%), Gaps = 26/175 (14%)
Frame = +1
Query: 58 LRHPNIVSL---QDVLMQDSRLYLIFEFLS-MDLKKYLDSIPPGQYMDSSLVKSYLYQIL 113
LRH N+VS+ + + +L E++ ++L+ L+ Q +DSS+ S Q+
Sbjct: 97 LRHVNVVSILGATSLHRFEDGAWLAMEYVGPLNLQTILND--HQQDIDSSMRLSLALQMA 270
Query: 114 QGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLA------------RAFGI------ 155
+G+ + HS ++H DLKP N L+ +++ADFG R G+
Sbjct: 271 RGLHYLHSINIVHLDLKPANCLLTRDLKLRIADFGCCHQLTPTGLDMGEREGGMAGNELE 450
Query: 156 --PIR-VYTHE-AITLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHG 206
P++ + +E A TL YR+PE+L G + S D++S+G ++ T++ + G
Sbjct: 451 LTPVQGAWKNELAGTLAYRAPELLKG-LQPSVRSDVYSLGITLWQMCTRQGPYEG 612
>21079
Length = 878
Score = 53.9 bits (128), Expect = 7e-08, Method: Compositional matrix adjust.
Identities = 42/141 (29%), Positives = 69/141 (48%), Gaps = 7/141 (4%)
Frame = +1
Query: 60 HPNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFC 119
HP ++ L D + L+ EF+ + + I + ++ QI G+ +
Sbjct: 1 HPKLLMLWDAFEAPRTMVLVMEFVGAG-ELFERVIRDDFVLTERDCVHFVRQICSGVGYM 177
Query: 120 HSRRVLHRDLKPQNLLI--DDKGTIKLADFGLARAF----GIPIRVYTHEAITLWYRSPE 173
H++ +LH DLKP+N+L D+ IK+ DFGLAR + + + T E I +PE
Sbjct: 178 HTQSILHLDLKPENVLCVSDNSNQIKIIDFGLARFYKPGDSLQVLFGTPEFI-----APE 342
Query: 174 VL-LGSARYSTPVDIWSIGTI 193
V+ ++T D+WSIG I
Sbjct: 343 VVNYDEINFTT--DMWSIGVI 399
>11185
Length = 473
Score = 50.8 bits (120), Expect = 7e-07, Method: Compositional matrix adjust.
Identities = 32/115 (27%), Positives = 53/115 (46%), Gaps = 22/115 (19%)
Frame = +1
Query: 105 VKSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIR---VYT 161
++ + ++ G+ + HS +L DL+P +L+D G +K ADFGL++ G +
Sbjct: 7 IRDFGIHLVTGLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKF 186
Query: 162 HEAITLW-------------------YRSPEVLLGSARYSTPVDIWSIGTIFAEL 197
EA W Y +PEV G A S D+W++G +F E+
Sbjct: 187 AEAGDQWNIQSAEEMMKQVPTSGSPTYMAPEVFQG-AEPSIMSDLWALGCVFYEM 348
>16708
Length = 1397
Score = 50.4 bits (119), Expect = 8e-07, Method: Compositional matrix adjust.
Identities = 46/207 (22%), Positives = 87/207 (42%), Gaps = 15/207 (7%)
Frame = -1
Query: 7 IEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH----PN 62
++ +G+G +G VY+ R +T + A+K L ++ E+ L +
Sbjct: 1388 LQVLGKGVFGKVYEARLLSTHEKAALKTSILCHH-------SLDEVEALGRIEGGFYLAQ 1230
Query: 63 IVSLQDVLMQDSRLYLIFEFLSMD-----LKKYLDSIPPGQYMDSSLVKSYLYQILQGIV 117
+ + ++ ++ F M Y + P ++ + ++V Q + +
Sbjct: 1229 MFGAWVTCLPFPKMNILLHFYEMGPLCNVYAHYKNKEMPIRWSNPAMVCCIAGQXVCALE 1050
Query: 118 FCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGI-PIRVYTHEA-----ITLWYRS 171
H V+H D+K N+L+D G KL D+G+A+ + + P TH + T + R
Sbjct: 1049 HIHELGVVHMDVKADNVLVDAHGNCKLTDYGIAQLYKVYPAPTETHSSGCTNKRTFYTRP 870
Query: 172 PEVLLGSARYSTPVDIWSIGTIFAELA 198
P + S R+S D IGT + L
Sbjct: 869 PATMTPSERFSEEGD--GIGTDYFRLG 795
>13840
Length = 446
Score = 48.5 bits (114), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 38/133 (28%), Positives = 65/133 (48%), Gaps = 5/133 (3%)
Frame = -1
Query: 2 EDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHP 61
ED + +IG G YG V K RHK T V+A+K+IR EE + +++ P
Sbjct: 395 EDMQDMGEIGRGNYGTVNKMRHKITSTVMAVKRIRSTVEEREQKQLLMDLDVVMRSNNCP 216
Query: 62 NIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQI----LQGIV 117
IV L ++ ++ E + L K+ + G+ M SS+ ++ L +I L+ +
Sbjct: 215 FIVQFYGALFKEGDCWICMELMETSLDKFYKFV-YGE-MQSSIPENILGKITVATLKALN 42
Query: 118 FCHSR-RVLHRDL 129
+ R++HRD+
Sbjct: 41 YLKEELRIIHRDV 3
>07291
Length = 833
Score = 48.5 bits (114), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 34/144 (23%), Positives = 66/144 (45%), Gaps = 8/144 (5%)
Frame = +1
Query: 111 QILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHE-----AI 165
QI G+ + +V+HR+L +N ++ + G ++L+D+G+ + P YT + +
Sbjct: 73 QIADGMAYLQEVKVVHRNLAARNCIVTEDGRLQLSDYGVTGSL-FPQSYYTADDSPARDL 249
Query: 166 TLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRA---LGT 222
W +PE + + +S+ D+W+ G + EL T+ + D E L + +
Sbjct: 250 VKWM-APET-IDNFHFSSKSDVWAFGVVLWELLTRGITPYPDVENSSLLPYLKEGHRMKK 423
Query: 223 PNNEVWPEVESLQDYKNTFPKWKP 246
P P E + N P+ +P
Sbjct: 424 PKQSPEPVYEMMTACWNESPEQRP 495
>01106
Length = 878
Score = 48.1 bits (113), Expect = 5e-06, Method: Compositional matrix adjust.
Identities = 41/148 (27%), Positives = 73/148 (49%), Gaps = 15/148 (10%)
Frame = +3
Query: 4 YTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNI 63
Y I K+G G + V+ T + VA+K ++ + TA+ E+ LLK +R ++
Sbjct: 324 YHVIRKLGWGHFSTVWLCWDLTCKRFVALKVVK---SAQHYTETALDEVKLLKCVRESDV 494
Query: 64 --------VSLQDVL----MQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSL--VKSYL 109
V L D + + + ++FE L +L L I Y + VK +
Sbjct: 495 ADPARAKCVQLLDDFKISGVNGTHVAMVFEVLGYNL---LKLIIRSNYQGIPIHNVKLII 665
Query: 110 YQILQGIVFCHSR-RVLHRDLKPQNLLI 136
Q+L+G+ + H++ R++H D+KP+N+LI
Sbjct: 666 RQVLEGLSYMHAKCRIIHTDIKPENILI 749
>16003
Length = 926
Score = 47.8 bits (112), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 33/88 (37%), Positives = 46/88 (52%)
Frame = -1
Query: 202 PLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNTFPKWKPGSLASHVKNLDENGL 261
P GD+++DQL +IF LGTP WP V SL DY F + L ++ L
Sbjct: 911 PFLPGDTDLDQLGKIFNMLGTPTETEWPAVTSLPDYIQ-FKHCQKQPLKEIFTAAGDDLL 735
Query: 262 DLLSKMLIYDPAKRISGKMALNHPYFND 289
+LL K+L +P R + AL PYF++
Sbjct: 734 ELLDKLLAMNPLHRCTATQALKMPYFSN 651
>20640
Length = 1492
Score = 47.0 bits (110), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 27/78 (34%), Positives = 44/78 (56%), Gaps = 2/78 (2%)
Frame = +1
Query: 122 RRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIP--IRVYTHEAITLWYRSPEVLLGSA 179
R +HRDL +N L+ +K++DFGLAR+ R H+AI + + E +L +
Sbjct: 1 RGYVHRDLATRNCLVGHDLVVKISDFGLARSVHSVDYYRGSEHDAIPIRWMPLEAILYN- 177
Query: 180 RYSTPVDIWSIGTIFAEL 197
++ST D+WS G + E+
Sbjct: 178 KFSTQSDVWSFGVVLWEI 231
>13078
Length = 773
Score = 47.0 bits (110), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 36/126 (28%), Positives = 55/126 (43%), Gaps = 16/126 (12%)
Frame = -1
Query: 181 YSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNT 240
+S P D+WSIG I EL T LF + L + R LG+ + + + + + +
Sbjct: 746 WSQPCDVWSIGCIMFELYTGYTLFQTHDNKEHLAMMERILGSLPYRMAKKTKKQKYFYHG 567
Query: 241 FPKWKPGSLAS------------HVKNLDENG----LDLLSKMLIYDPAKRISGKMALNH 284
W S A +VK+ D DL+ KML Y+ + R S + A+ H
Sbjct: 566 RLDWDEKSSAGRYVRDNVKPLRRYVKDPDNEDHQQLFDLMDKMLSYEVSTRYSLRQAMRH 387
Query: 285 PYFNDL 290
P+F L
Sbjct: 386 PFFRKL 369
>36481
Length = 806
Score = 46.2 bits (108), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 36/134 (26%), Positives = 61/134 (45%), Gaps = 6/134 (4%)
Frame = +2
Query: 11 GEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPN------IV 64
GEGT+G V + + G +A+K I+ + A EI++L++LR + V
Sbjct: 389 GEGTFGKVVQCKDLLKGDDIALKIIK---NVDKYREAAKLEINVLEKLREKDPHAKHMCV 559
Query: 65 SLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCHSRRV 124
+ D + + F L + + +L G Y V+ YQ+ + F H ++
Sbjct: 560 QMLDWFDYHGHVCISFHMLGLSVFDFLKDNSYGAY-PIEQVRHISYQLCYAVNFLHENQL 736
Query: 125 LHRDLKPQNLLIDD 138
H DLKP+N+L D
Sbjct: 737 THTDLKPENILFVD 778
>12786
Length = 460
Score = 45.8 bits (107), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 35/138 (25%), Positives = 61/138 (44%), Gaps = 22/138 (15%)
Frame = -3
Query: 98 QYMDSSLVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPI 157
Q +D ++K Y ++L+ + H+ V+H DLKP N ++ G +KL DFG+A
Sbjct: 425 QGLDRMMIKFYWREMLRAVKALHNEGVIHSDLKPANFML-VAGNLKLIDFGIANTLQQDK 249
Query: 158 RVYTHEAI--TLWYRSPEVLLGSA-----------------RYSTPV--DIWSIGTIFAE 196
++ T Y SPE ++ + +Y V D+WS+G I
Sbjct: 248 TSVLKDSRVGTPSYMSPEAIMAACDDSADDSMEEDGHRTKPKYKVGVRSDVWSLGCILYN 69
Query: 197 LA-TKKPLFHGDSEIDQL 213
+ + P H + + +L
Sbjct: 68 MVYGRTPFQHIKNNMGKL 15
>18996
Length = 491
Score = 45.8 bits (107), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 26/79 (32%), Positives = 46/79 (58%), Gaps = 3/79 (3%)
Frame = +2
Query: 125 LHRDLKPQNLLIDDKGTIKLADFGLAR---AFGIPIRVYTHEAITLWYRSPEVLLGSARY 181
+HRDL +N+L+D + +K++DFGLA+ A G + + WY SPE + + ++
Sbjct: 2 IHRDLAARNILVD-RSCVKISDFGLAQFANADGYYYGISQRDIPIKWY-SPEA-IETCKF 172
Query: 182 STPVDIWSIGTIFAELATK 200
S+ D+WS G E+ ++
Sbjct: 173 SSYSDVWSYGVTLFEMFSR 229
>11404
Length = 563
Score = 45.4 bits (106), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 40/135 (29%), Positives = 70/135 (51%), Gaps = 8/135 (5%)
Frame = +1
Query: 10 IGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKEL-RHPN-----I 63
IG+G++G V K T + VA+K I+ ++ + A E+ LL+ + RH I
Sbjct: 163 IGKGSFGQVVKAYDHTDNEQVAIKIIK---NKKPFLNQAQIEVKLLEMMNRHDTDNKYYI 333
Query: 64 VSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCHS-- 121
V L+ M S L L+FE LS +L L + + + +L + + Q+ ++F +
Sbjct: 334 VRLKRHFMFRSHLCLVFELLSYNLYDLLRN-TNFRGVSLNLTRKFAQQLCTALLFLATPE 510
Query: 122 RRVLHRDLKPQNLLI 136
++H DLKP+N+L+
Sbjct: 511 MSIIHCDLKPENILL 555
>06358
Length = 1517
Score = 43.9 bits (102), Expect = 7e-05, Method: Compositional matrix adjust.
Identities = 71/320 (22%), Positives = 129/320 (40%), Gaps = 33/320 (10%)
Frame = +3
Query: 4 YTKIEKIGEGTYGVVYKGRHKTT---GQVVAMKKIRLES----EEEGVPSTAIREISLLK 56
Y ++ G G V+ K+T V +K ++ + E + + L
Sbjct: 12 YNQVASAGPGLLWKVFAASKKSTKEEASVFVFEKKSVDRYSRRDREAIVEVLRVGVQQLT 191
Query: 57 ELRHPNIVSLQDVLMQDSRLYLIFE----FLSM-DLKKYLDSIP--PGQYMDSSL----V 105
+LRHP I+++ + L ++SR L F F S+ ++ L SI P + D L +
Sbjct: 192 KLRHPKILAVINPL-EESRETLAFATEPVFASLANVLGDLSSIXTVPKELQDYQLYDVEI 368
Query: 106 KSYLYQILQGIVFCHS-RRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEA 164
K L Q+ + + F H+ +++HR++ P+ +++ G+ KLA + P
Sbjct: 369 KHGLLQVTEALGFLHNDAKMMHRNVCPEAIMLTKLGSWKLAGYEFCVRSSDPQSTDPSYP 548
Query: 165 ITLW-------------YRSPEVLLGSARYSTPVDIWSIG-TIFAELATKKPLFHGDSEI 210
W + +PE +L + + T D++S+G +++ A KPLF + E+
Sbjct: 549 FYEWRSDIAPVTQPHLDFMAPEYVL-TMQCGTGSDMFSLGLLVYSVFAKGKPLFECNGEL 725
Query: 211 DQLFRIFRALGTPNNEVWPEVESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIY 270
F++ E L+ + + P L HVK L L
Sbjct: 726 SA----FKS----------NAEELRHMRVSLLGVVPEDLRDHVKLL-----------LNI 830
Query: 271 DPAKRISGKMALNHPYFNDL 290
+PA R P+F D+
Sbjct: 831 EPAVRPDAAQLSKVPFFEDV 890
>05084
Length = 1324
Score = 43.5 bits (101), Expect = 9e-05, Method: Compositional matrix adjust.
Identities = 30/95 (31%), Positives = 50/95 (52%), Gaps = 3/95 (3%)
Frame = +2
Query: 206 GDSEIDQLFRIFRALGTPNNEVWPEVE-SLQDYKNTFPKWK--PGSLASHVKNLDENGLD 262
GDS +DQL I + LGTP E E+ + ++K FP+ K P + + E +
Sbjct: 8 GDSGVDQLVEIIKVLGTPTREQIREMNPNYSEFK--FPQIKAHPWTKVFRPRTPPE-AIQ 178
Query: 263 LLSKMLIYDPAKRISGKMALNHPYFNDLDNQIKKM 297
L+S++L Y P+ RI A H +F++L + ++
Sbjct: 179 LVSRLLEYTPSARIQPMEACAHAFFDELRDPASRL 283
>26156
Length = 479
Score = 41.6 bits (96), Expect(2) = 1e-04, Method: Compositional matrix adjust.
Identities = 23/86 (26%), Positives = 43/86 (50%), Gaps = 2/86 (2%)
Frame = -1
Query: 1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLE--SEEEGVPSTAIREISLLKEL 58
+ D+ + IG G+Y V + HK T ++ AMK I+ E +++E + +
Sbjct: 392 LTDFLLLRVIGRGSYAKVLQVEHKRTKRIYAMKVIKKELVNDDEDIDWVQTEKHVFETAT 213
Query: 59 RHPNIVSLQDVLMQDSRLYLIFEFLS 84
+P +V L +SRL+ + EF++
Sbjct: 212 NYPFLVGLHSCFQSESRLFFVIEFVN 135
Score = 21.2 bits (43), Expect(2) = 1e-04, Method: Compositional matrix adjust.
Identities = 9/23 (39%), Positives = 14/23 (60%)
Frame = -3
Query: 108 YLYQILQGIVFCHSRRVLHRDLK 130
Y +I + F H R +++RDLK
Sbjct: 72 YSAEICLALNFLHKRGIVYRDLK 4
>16350
Length = 1108
Score = 43.1 bits (100), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 31/80 (38%), Positives = 41/80 (51%), Gaps = 3/80 (3%)
Frame = +2
Query: 128 DLKPQNLLIDDKGT---IKLADFGLARAFGIPIRVYTHEAITLWYRSPEVLLGSARYSTP 184
D KP+ +++ T +K+AD G A +T + T YR EVL+G A Y TP
Sbjct: 305 DNKPECDPVNEICTDFPVKIADLGNAC---WTYHHFTEDIQTRQYRCLEVLIG-AGYGTP 472
Query: 185 VDIWSIGTIFAELATKKPLF 204
DIWS + ELAT LF
Sbjct: 473 ADIWSTACMAFELATGDYLF 532
Score = 30.0 bits (66), Expect = 1.2, Method: Compositional matrix adjust.
Identities = 10/27 (37%), Positives = 16/27 (59%)
Frame = +3
Query: 262 DLLSKMLIYDPAKRISGKMALNHPYFN 288
D L+ ML +DP +R + +L HP+
Sbjct: 762 DFLAPMLEFDPEQRATAAQSLQHPWLK 842
>17300
Length = 480
Score = 42.4 bits (98), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 27/97 (27%), Positives = 48/97 (49%), Gaps = 16/97 (16%)
Frame = +1
Query: 125 LHRDLKPQNLLIDDKGTIKLADFGLARAF--------------GIPIRVYTHEAITLWYR 170
+HRDL +N+L+++ K+ADFGL+R IP+R EAI YR
Sbjct: 40 VHRDLAARNILVNEILVCKVADFGLSREIESDTTEGAYTTKGGKIPVRWTAPEAIA--YR 213
Query: 171 SPEVLLGSARYSTPVDIWSIGTIFAELAT--KKPLFH 205
++++ D+WS G + E+ + ++P ++
Sbjct: 214 ---------KFTSASDVWSFGVVMWEVMSYGERPYWN 297
>31789
Length = 676
Score = 41.6 bits (96), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 33/114 (28%), Positives = 56/114 (49%), Gaps = 6/114 (5%)
Frame = +2
Query: 9 KIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQD 68
+IG G++ VYKG G VA +++ + + E +LKEL+HPNIV D
Sbjct: 341 EIGRGSFKTVYKGLDTELGVAVAWCELQDKKWNKTERQRFKEEAEMLKELQHPNIVRFFD 520
Query: 69 VLMQDSR-----LYLIFEFL-SMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGI 116
+ + + L+ E + S LK YL ++ ++K++ QIL+G+
Sbjct: 521 YWEEHNHRNRKVIILVTELMTSGTLKTYLKRFKK---INLKVLKNWCRQILKGL 673
>37602
Length = 804
Score = 40.4 bits (93), Expect = 8e-04, Method: Compositional matrix adjust.
Identities = 16/37 (43%), Positives = 27/37 (72%)
Frame = -1
Query: 111 QILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADF 147
+ L+G+ + H R +HRD+K N+L+ ++G +KLADF
Sbjct: 195 ETLKGLHYLHRRGKMHRDIKGANILLTEEGDVKLADF 85
Score = 30.4 bits (67), Expect = 1.0, Method: Compositional matrix adjust.
Identities = 12/30 (40%), Positives = 19/30 (63%)
Frame = -2
Query: 1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVV 30
++D+ I+++G GTYG VYK + T G
Sbjct: 512 LDDFELIQRVGSGTYGDVYKAKA*TQGACC 423
>02638
Length = 1490
Score = 40.0 bits (92), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 31/123 (25%), Positives = 49/123 (39%)
Frame = +1
Query: 166 TLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNN 225
T+ + +PEVL G + Y D+WS+G + E+ T +P ++ + L IF+ + +
Sbjct: 25 TIAFMAPEVLRGES-YGRACDVWSVGCVMIEMCTCRPPWNSHDISNHLALIFKIASSVDP 201
Query: 226 EVWPEVESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHP 285
PE N+ DL+ + L D R S K L HP
Sbjct: 202 PPIPE------------------------NMSPPVRDLMLRCLEQDSDFRPSAKDLLMHP 309
Query: 286 YFN 288
F
Sbjct: 310 LFT 318
>20152
Length = 445
Score = 40.0 bits (92), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 31/120 (25%), Positives = 46/120 (38%)
Frame = +1
Query: 172 PEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEV 231
PE+LLG + + VD+WS+G I L + F ++ + L I
Sbjct: 1 PEILLGDSYDAPAVDVWSLGVILYMLVVGEAPFQEANDSETLTMIM-------------- 138
Query: 232 ESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLD 291
D + P ++ DL+ KML +P R S L HP+ ND D
Sbjct: 139 ----DCRYQIP-----------PHISHKCQDLIEKMLQREPVDRASLPHILAHPWLNDGD 273
>25019
Length = 730
Score = 40.0 bits (92), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 22/63 (34%), Positives = 35/63 (55%)
Frame = +3
Query: 132 QNLLIDDKGTIKLADFGLARAFGIPIRVYTHEAITLWYRSPEVLLGSARYSTPVDIWSIG 191
+N+L+D G +KL DFGL + RV T+ Y +PE+L + + VD WS+G
Sbjct: 261 ENVLLDKDGHVKLTDFGLCKEAITGTRVTHTFCGTIEYMAPEILTRTG-HGKAVDWWSLG 437
Query: 192 TIF 194
+ +
Sbjct: 438 SSY 446
>07836
Length = 1478
Score = 39.7 bits (91), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 40/139 (28%), Positives = 68/139 (48%), Gaps = 15/139 (10%)
Frame = -1
Query: 27 GQVVAMKKIRLESEEEGVPSTAIREISLLKE--LRHPNIVSLQDVLMQDS----RLYLIF 80
G+ VA+K I +EE ++ RE L + LRH NI+ ++ + +L+LI
Sbjct: 1478 GENVAVK-IFFTTEE----ASWFRETELYQTVLLRHENILGFIAADIKGTGSWTQLFLIT 1314
Query: 81 EFL-SMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCHSR--------RVLHRDLKP 131
++ + L YL S + +DSS + + + + G+ H + HRD+K
Sbjct: 1313 DYHENGSLHDYLLS----RVLDSSEMLALAHSAICGLAHLHIEIFGTRGKPAIAHRDIKS 1146
Query: 132 QNLLIDDKGTIKLADFGLA 150
+N+L+ GT +AD GLA
Sbjct: 1145 KNILVKKNGTCCIADLGLA 1089
>00638
Length = 1595
Score = 39.3 bits (90), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 13/33 (39%), Positives = 25/33 (75%)
Frame = +2
Query: 105 VKSYLYQILQGIVFCHSRRVLHRDLKPQNLLID 137
++ YLY++++ + FCHS ++HRD+KP L++
Sbjct: 422 IRFYLYELMKALDFCHSMGIMHRDVKPSPPLVN 520
>26009
Length = 886
Score = 38.1 bits (87), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 14/32 (43%), Positives = 25/32 (78%)
Frame = +3
Query: 105 VKSYLYQILQGIVFCHSRRVLHRDLKPQNLLI 136
KS + Q++ + F HS++++HRD+KP+N+LI
Sbjct: 717 AKSVMKQLVSALDFMHSKQLVHRDIKPENVLI 812
>12672
Length = 773
Score = 38.1 bits (87), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 28/96 (29%), Positives = 47/96 (48%), Gaps = 10/96 (10%)
Frame = +3
Query: 114 QGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEAITLWYRSPE 173
GI + + +HRD+K N+L+D + T K+ DF A P + E T+ ++
Sbjct: 24 SGIQYLNDNGHVHRDIKTANILLDSEYTAKVGDF--ATVVSAP----SGEGKTV--QNAS 179
Query: 174 VLLGSARY----------STPVDIWSIGTIFAELAT 199
V++G+A Y ST +D +S G + E+ T
Sbjct: 180 VVIGTAAYLAPEAIHFDVSTKLDSYSFGVVLLEVIT 287
>00394
Length = 548
Score = 37.7 bits (86), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 21/60 (35%), Positives = 31/60 (51%)
Frame = -2
Query: 9 KIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQD 68
+IG G++ VYKG G VA +++ + + E +LKEL+HPNIV D
Sbjct: 277 EIGRGSFKTVYKGLDTELGVAVAWCELQDKKWNKAERQRFKEEAEMLKELQHPNIVRFFD 98
>21800
Length = 855
Score = 37.4 bits (85), Expect = 0.007, Method: Compositional matrix adjust.
Identities = 36/119 (30%), Positives = 59/119 (49%), Gaps = 20/119 (16%)
Frame = +2
Query: 47 TAIREISLLKELRHPN--------IVSLQDVL----MQDSRLYLIFEFLSMDLKKYL--- 91
TA+ EI LLK +R+ + V L D + + + ++FE L +L K +
Sbjct: 431 TALDEIKLLKCVRNSDETDPAREKSVQLLDDFKISGVNGTHVCMVFEVLGYNLLKLIIRS 610
Query: 92 --DSIPPGQYMDSSLVKSYLYQILQGIVFCHSR-RVLHRDLKPQNLLI--DDKGTIKLA 145
IP VK + Q+L+G+ + H++ ++H D+KP+N+LI DD KLA
Sbjct: 611 NYQGIPVHN------VKLIIRQVLEGLNYLHAKCNIIHTDIKPENILICVDDNYIRKLA 769
>15549
Length = 470
Score = 36.2 bits (82), Expect = 0.015, Method: Compositional matrix adjust.
Identities = 14/39 (35%), Positives = 28/39 (71%)
Frame = -1
Query: 2 EDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESE 40
+++ IE++G+G YG+V++ ++K Q A+K+I L S+
Sbjct: 218 DEFECIEQMGKGGYGIVFRAKNKVDEQEYAVKRIALPSD 102
>20773
Length = 391
Score = 34.3 bits (77), Expect = 0.056, Method: Compositional matrix adjust.
Identities = 11/35 (31%), Positives = 25/35 (71%)
Frame = -1
Query: 252 HVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPY 286
H + ++ +L+ ++L YDP++R++ +AL+HP+
Sbjct: 334 HTTVVTQHFYNLVQRLLTYDPSQRLTPDLALSHPF 230
>17644
Length = 463
Score = 33.9 bits (76), Expect = 0.087, Method: Compositional matrix adjust.
Identities = 11/35 (31%), Positives = 24/35 (68%)
Frame = +3
Query: 252 HVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPY 286
H + ++ BL+ ++L YDP++R++ +AL+HP+
Sbjct: 57 HTTVVTQHFYBLVQRLLTYDPSQRLTPDLALSHPF 161
>18481
Length = 437
Score = 32.7 bits (73), Expect = 0.17, Method: Compositional matrix adjust.
Identities = 16/46 (34%), Positives = 26/46 (56%), Gaps = 3/46 (6%)
Frame = -1
Query: 111 QILQGIVFCHSRRVLHRDLKPQNLLID---DKGTIKLADFGLARAF 153
Q+L + F H + +HRDLKP N L+ + + DFGL++ +
Sbjct: 173 QLLSRLEFIHQKCFIHRDLKPDNFLMGLGRHCHRLYIIDFGLSKRY 36
>32357
Length = 625
Score = 32.7 bits (73), Expect = 0.17, Method: Compositional matrix adjust.
Identities = 14/30 (46%), Positives = 22/30 (73%)
Frame = -2
Query: 4 YTKIEKIGEGTYGVVYKGRHKTTGQVVAMK 33
Y ++KIG G++G +Y G H T+G+ VA+K
Sbjct: 432 YRLMKKIGSGSFGEIYLGVHNTSGEEVAVK 343
>38560
Length = 479
Score = 32.7 bits (73), Expect = 0.21, Method: Compositional matrix adjust.
Identities = 31/121 (25%), Positives = 48/121 (39%), Gaps = 1/121 (0%)
Frame = -3
Query: 169 YRSPEVLLGSARYSTPVDIWSIGT-IFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEV 227
Y +PE++ G + DIWS+G ++A L P D + L
Sbjct: 387 YAAPELISGLEYLGSEADIWSMGVLLYALLCGYLPF--DDEKXSHL-------------- 256
Query: 228 WPEVESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYF 287
+ Q K+ P+W L E+ LL ML DP+ RI+ + L+H +
Sbjct: 255 ---*QKNQKRKDEVPEW-----------LSEDTTKLLEGMLQTDPSHRITIRRLLDHHWL 118
Query: 288 N 288
N
Sbjct: 117 N 115
>35032
Length = 465
Score = 32.0 bits (71), Expect = 0.30, Method: Compositional matrix adjust.
Identities = 12/27 (44%), Positives = 19/27 (70%)
Frame = +3
Query: 261 LDLLSKMLIYDPAKRISGKMALNHPYF 287
DL+ ++L YDP+KR++ AL HP+
Sbjct: 144 FDLVKRLLNYDPSKRLTPXXALAHPFL 224
>15931
Length = 447
Score = 31.6 bits (70), Expect = 0.41, Method: Compositional matrix adjust.
Identities = 13/30 (43%), Positives = 19/30 (63%)
Frame = +1
Query: 261 LDLLSKMLIYDPAKRISGKMALNHPYFNDL 290
DL+ KML Y+ + R S + A+ HP+F L
Sbjct: 76 FDLMDKMLSYEVSTRYSLRQAMRHPFFRKL 165
>20513
Length = 405
Score = 30.0 bits (66), Expect = 1.3, Method: Compositional matrix adjust.
Identities = 10/25 (40%), Positives = 16/25 (64%)
Frame = -1
Query: 262 DLLSKMLIYDPAKRISGKMALNHPY 286
D L+ ML +DP +R + +L HP+
Sbjct: 282 DFLAPMLEFDPEQRATAAQSLQHPW 208
>29360
Length = 363
Score = 29.3 bits (64), Expect = 1.9, Method: Compositional matrix adjust.
Identities = 29/121 (23%), Positives = 54/121 (44%), Gaps = 8/121 (6%)
Frame = +3
Query: 24 KTTGQVVAMKKIRLESEEEGVPSTAIR---EISLLKELRHP-----NIVSLQDVLMQDSR 75
K T ++VA+K ++ PS A + E+S+L+ L N V + +
Sbjct: 18 KGTSEIVAIKILK------NHPSYARQGQIEVSILQRLSQESADDYNFVRAFECFQHKNH 179
Query: 76 LYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCHSRRVLHRDLKPQNLL 135
L+FE L +L +L Q + ++ Q+L + ++H DLKP+N++
Sbjct: 180 TCLVFEMLEQNLYDFLKQ-NKFQPLPLKYIRPITQQVLTALRKLKQLGLIHADLKPENIM 356
Query: 136 I 136
+
Sbjct: 357 L 359
>01007
Length = 897
Score = 28.9 bits (63), Expect = 3.0, Method: Compositional matrix adjust.
Identities = 16/46 (34%), Positives = 26/46 (56%)
Frame = -1
Query: 78 LIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCHSRR 123
LI + + L+ L S+ GQ ++S+ VK Y+ GI+F H +R
Sbjct: 369 LICHCIFIALRNRLLSLLTGQILESA-VKCYVMLFYVGIIFSHGKR 235
>21210
Length = 518
Score = 28.5 bits (62), Expect = 3.1, Method: Compositional matrix adjust.
Identities = 19/57 (33%), Positives = 27/57 (47%), Gaps = 4/57 (7%)
Frame = +3
Query: 169 YRSPEVL---LGSARYSTPVDIWSIGTIFAELATKK-PLFHGDSEIDQLFRIFRALG 221
Y +PE + S Y D+WS+G ELAT + P S DQL ++ R +
Sbjct: 18 YMAPERIDPRASSHGYDVRSDVWSLGITLMELATGRFPYRKWVSIFDQLQQVVRGVA 188
>17516
Length = 453
Score = 27.7 bits (60), Expect = 5.7, Method: Compositional matrix adjust.
Identities = 12/29 (41%), Positives = 17/29 (58%)
Frame = -3
Query: 169 YRSPEVLLGSARYSTPVDIWSIGTIFAEL 197
Y +PEVLL +Y D++S+ I EL
Sbjct: 421 YMAPEVLLQKGQYDMKADVYSLAIILWEL 335
>13305
Length = 549
Score = 27.7 bits (60), Expect = 5.7, Method: Compositional matrix adjust.
Identities = 11/38 (28%), Positives = 19/38 (50%)
Frame = +2
Query: 181 YSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFR 218
Y+T D+WS G + E+ T + ++ QLF +
Sbjct: 56 YTTQSDVWSFGVVLWEIFTLGGTPYSSTDTQQLFAFLK 169
>17806
Length = 433
Score = 27.3 bits (59), Expect = 8.4, Method: Compositional matrix adjust.
Identities = 28/102 (27%), Positives = 50/102 (49%), Gaps = 8/102 (7%)
Frame = +1
Query: 7 IEKIGEGTYGVVYK--GRHKTTGQ-----VVAMKKIRLESEEEGVPSTAIREISLLKELR 59
++++G G +G V + TTG VV M K +E+ + E++ +EL
Sbjct: 64 LKELGTGWFGKVIESDAERITTGVSRSKVVVKMLKDDATKDEQLL---FFEEVAPFRELD 234
Query: 60 HPNIVSLQDVLMQDSRLYLIFEFLSM-DLKKYLDSIPPGQYM 100
HPNIV L + + + ++ E ++ +LK+YL + Q M
Sbjct: 235 HPNIVRLLGQCTEMNPMLMLMECAALGNLKQYLRNHRHQQAM 360
>26052
Length = 562
Score = 26.9 bits (58), Expect = 8.8, Method: Compositional matrix adjust.
Identities = 11/27 (40%), Positives = 19/27 (70%)
Frame = -1
Query: 10 IGEGTYGVVYKGRHKTTGQVVAMKKIR 36
+G G++G V +HK TG+ +A+K I+
Sbjct: 367 LGVGSFGKVMALQHKDTGETLAVKNIQ 287
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000339247 | hsapiens_gene_ensembl | Casein kinase
II subunit alpha (EC 2.7.11.1) (CK II).
[Source:Uniprot/SWISSPROT;Acc:P68400]
(391 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
03508 402 e-112
00638 145 4e-47
12704 125 2e-29
01060 106 2e-23
14126 103 8e-23
01707 97 2e-20
04591 91 9e-19
04138 87 1e-17
29581 86 3e-17
32000 85 4e-17
01756 77 1e-14
21079 76 2e-14
15910 70 1e-12
23319 69 4e-12
26560 69 4e-12
00300 62 3e-10
12721 62 5e-10
13212 61 6e-10
12786 61 7e-10
01392 60 1e-09
30755 60 1e-09
28638 60 2e-09
01966 60 2e-09
14420 57 9e-09
27405 57 1e-08
18921 57 2e-08
31885 55 4e-08
03294 55 4e-08
19761 55 5e-08
26711 55 5e-08
18484 55 6e-08
09606 54 9e-08
19094 54 1e-07
18287 54 1e-07
13592 53 2e-07
18401 50 1e-06
03240 50 2e-06
21433 49 3e-06
13078 49 5e-06
31489 47 9e-06
13066 47 2e-05
04852 47 2e-05
07940 46 3e-05
11185 45 7e-05
00715 44 1e-04
17975 42 4e-04
37602 41 9e-04
14116 41 0.001
01718 40 0.001
01106 39 0.003
26009 39 0.004
05084 38 0.006
00392 38 0.006
06358 38 0.006
21800 37 0.014
32359 28 0.023
27546 36 0.030
02638 35 0.045
28157 35 0.060
18481 35 0.062
29360 34 0.10
15931 33 0.14
19301 33 0.18
26909 33 0.20
29590 33 0.24
11801 33 0.24
14104 33 0.27
12672 31 0.90
27274 30 1.2
35032 30 1.5
37063 30 1.6
17932 30 1.8
16350 30 2.0
20773 29 2.9
20513 29 3.5
18663 29 4.0
28419 28 6.1
20152 28 8.3
>03508
Length = 1463
Score = 402 bits (1032), Expect = e-112, Method: Compositional matrix adjust.
Identities = 187/233 (80%), Positives = 201/233 (86%)
Frame = +1
Query: 1 MSGPVPSRARVYTDVNTHRPREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINIT 60
+S P+PSRARVY DVNTH+ REYWDYESHVVEWGNQDDYQ+VRKLGRGKYSEVFEAIN+T
Sbjct: 481 VSMPLPSRARVYADVNTHKAREYWDYESHVVEWGNQDDYQIVRKLGRGKYSEVFEAINVT 660
Query: 61 NNEXXXXXXXXXXXXXXXXXXXXXLENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTD 120
NNE LENLRGG N+ITL IVKDPVSRTPAL+FEHVNNTD
Sbjct: 661 NNEKCVIKILKPVKKKKIKREIKILENLRGGTNVITLLAIVKDPVSRTPALIFEHVNNTD 840
Query: 121 FKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAE 180
FKQLYQT TDYDIRFY+YE++KALD+CHSMGIMHRDVKPHNVMIDHE++KLRLIDWGLAE
Sbjct: 841 FKQLYQTFTDYDIRFYLYELMKALDFCHSMGIMHRDVKPHNVMIDHENKKLRLIDWGLAE 1020
Query: 181 FYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFF 233
FYHPG EYNVRVASRYFKGPELL+DYQMYDYSLDMWSLGCM ASMIFRKEP
Sbjct: 1021FYHPGMEYNVRVASRYFKGPELLLDYQMYDYSLDMWSLGCMFASMIFRKEPLL 1179
Score = 186 bits (471), Expect = 2e-47, Method: Compositional matrix adjust.
Identities = 89/115 (77%), Positives = 97/115 (84%), Gaps = 3/115 (2%)
Frame = +2
Query: 216 WSLGCMLASM---IFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDI 272
W+ G A + K PFFHGHDNYDQLVRIAKVLGT+DLY YI+KY I+LDPRFNDI
Sbjct: 1118 WTCGVWAACLPA*SSGKSPFFHGHDNYDQLVRIAKVLGTDDLYGYIEKYQIDLDPRFNDI 1297
Query: 273 LGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTV 327
LGRHSRKRWERFVHSENQHL+SPEALDFLDKLLRYDH RLTAREAM+HPYF +
Sbjct: 1298 LGRHSRKRWERFVHSENQHLISPEALDFLDKLLRYDHNERLTAREAMDHPYFXPI 1462
>00638
Length = 1595
Score = 145 bits (365), Expect(2) = 4e-47, Method: Compositional matrix adjust.
Identities = 65/75 (86%), Positives = 71/75 (94%)
Frame = +2
Query: 85 LENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKAL 144
LENLRGG N+ITL IVKDPVSRTPAL+FEHVNNTDFKQLYQT TDYDIRFY+YE++KAL
Sbjct: 278 LENLRGGTNVITLLAIVKDPVSRTPALIFEHVNNTDFKQLYQTFTDYDIRFYLYELMKAL 457
Query: 145 DYCHSMGIMHRDVKP 159
D+CHSMGIMHRDVKP
Sbjct: 458 DFCHSMGIMHRDVKP 502
Score = 60.8 bits (146), Expect(2) = 4e-47, Method: Compositional matrix adjust.
Identities = 27/29 (93%), Positives = 29/29 (100%)
Frame = +1
Query: 35 NQDDYQLVRKLGRGKYSEVFEAINITNNE 63
NQDDYQ+VRKLGRGKYSEVFEAIN+TNNE
Sbjct: 127 NQDDYQIVRKLGRGKYSEVFEAINVTNNE 213
>12704
Length = 641
Score = 125 bits (315), Expect = 2e-29, Method: Compositional matrix adjust.
Identities = 56/63 (88%), Positives = 61/63 (96%)
Frame = +3
Query: 1 MSGPVPSRARVYTDVNTHRPREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINIT 60
++ P+PSRARVY DVNTH+PREYWDYESHVVEWGNQDDYQ+VRKLGRGKYSEVFEAINIT
Sbjct: 423 ITMPLPSRARVYADVNTHKPREYWDYESHVVEWGNQDDYQIVRKLGRGKYSEVFEAINIT 602
Query: 61 NNE 63
NNE
Sbjct: 603 NNE 611
>01060
Length = 1800
Score = 106 bits (264), Expect = 2e-23, Method: Compositional matrix adjust.
Identities = 66/242 (27%), Positives = 123/242 (50%), Gaps = 7/242 (2%)
Frame = +1
Query: 93 NIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQ------TLTDYDIRFYMYEILKALDY 146
NI+ L D++ + LVFE ++ D K L ++ Y+++I+ + +
Sbjct: 253 NIVCLEDVIME--DERLFLVFEFLS-MDLKMYIDKFPEGVVLDRRLVKSYVFQIVTGIXF 423
Query: 147 CHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAE-FYHPGQEYNVRVASRYFKGPELLVD 205
CH I+HRD+KP N++I+H +++ D+G+A F P + Y V + +++ PE+L+
Sbjct: 424 CHQRRIVHRDLKPQNLLINHTG-AIKIADFGMARTFALPVRAYTHEVVTLWYRAPEILMG 600
Query: 206 YQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIEL 265
Y +D+WS+G + A M+ R P F G DQL +I +++GT + + + +
Sbjct: 601 ASKYSTPVDVWSIGTIFADMLIRT-PIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKL-- 771
Query: 266 DPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFY 325
P FN + W+ SE + LD +++ L+ D R++ ++ ++H YF
Sbjct: 772 -PAFNGMF-----PLWKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYFL 933
Query: 326 TV 327
V
Sbjct: 934 NV 939
>14126
Length = 1265
Score = 103 bits (258), Expect = 8e-23, Method: Compositional matrix adjust.
Identities = 69/243 (28%), Positives = 122/243 (50%), Gaps = 10/243 (4%)
Frame = +3
Query: 92 PNIITLADIVKDPVSRTPA---LVFEHVNNTDFKQLYQT----LTDYDIRFYMYEILKAL 144
PN++ L D+ + ++ LVFE++ + L + L I+ M ++L +
Sbjct: 378 PNVVRLLDVSHNTITDREIRLNLVFEYIEHDLATYLAKCPSPGLGPDRIKDLMLQLLNGV 557
Query: 145 DYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLV 204
D+ HS I+HRD+KP N++I + R L+L D+GLA Y V + +++ PE+L+
Sbjct: 558 DFLHSNRIVHRDLKPQNLLISKDGR-LKLADFGLARIYSFHMALTTVVVTLWYRSPEVLM 734
Query: 205 DYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIE 264
+ Y S+D+WS GC+ A + F + F G +DQL +I +V+G D+ + ++
Sbjct: 735 QAE-YGTSVDIWSCGCIFAEL-FTRRALFKGSSEFDQLKKIFEVIGLPPAGDWPEGVSVH 908
Query: 265 LDPRFNDILGRHSRKRWERFVHSENQHLV---SPEALDFLDKLLRYDHQSRLTAREAMEH 321
R + Q LV P+A D ++K+L + R+++RE++ H
Sbjct: 909 -------------RNSFRPTPPVPLQTLVPEMDPQAKDLMEKMLVFKSGRRISSRESLLH 1049
Query: 322 PYF 324
PY
Sbjct: 1050PYL 1058
>01707
Length = 757
Score = 96.7 bits (239), Expect = 2e-20, Method: Compositional matrix adjust.
Identities = 63/223 (28%), Positives = 114/223 (51%), Gaps = 9/223 (4%)
Frame = +1
Query: 37 DDYQLVRKLGRGKYSEVFEAINITNNEXXXXXXXXXXX-----XXXXXXXXXXLENLRGG 91
+ Y+ + K+G G Y VF+ N ++ L+ L+
Sbjct: 64 EKYEKIGKIGEGSYGVVFKCRNKETSQLVAIKKFVESEDDPLIKKIAMREIRMLKQLKH- 240
Query: 92 PNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQ---TLTDYDIRFYMYEILKALDYCH 148
PN++ L ++ + + LVF++V++T +L + L + ++ +Y+ L A+++CH
Sbjct: 241 PNLVRLIEVFRR--KKRLHLVFDYVDHTLLNELDRYPRGLPEPMVKRIIYQTLLAVNFCH 414
Query: 149 SMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYH-PGQEYNVRVASRYFKGPELLVDYQ 207
+HRDVKP N++I + +++L D+G A PG EY VA+R+++ PELLV
Sbjct: 415 QYNTIHRDVKPENILITRQG-QVKLCDFGFARILTGPGDEYTDYVATRWYRAPELLVGDT 591
Query: 208 MYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLG 250
Y +D+W++GC+ A ++ + + G + DQL I K LG
Sbjct: 592 QYGPPVDVWAIGCVFAELL-TGQALWPGRSDVDQLHLIRKTLG 717
>04591
Length = 1117
Score = 90.5 bits (223), Expect = 9e-19, Method: Compositional matrix adjust.
Identities = 68/244 (27%), Positives = 117/244 (47%), Gaps = 10/244 (4%)
Frame = -2
Query: 93 NIITLADIV---KDPVSR---TPALVFEHVNNTDFKQLYQTL----TDYDIRFYMYEILK 142
N++ L +I P +R T L+FE+ + D L L + D + M ++L
Sbjct: 1038 NVVQLQEICHTQAGPYNRYKSTFYLIFEYCD-YDLAGLLNNLRVKFSLADKKNLMSQLLN 862
Query: 143 ALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPEL 202
L Y H+ I+HRD+K N+++ + L+L D+GL+ + + RV + +++ PEL
Sbjct: 861 GLFYIHTKQILHRDIKAANILLTRDG-VLKLADFGLSRPWVKSKRLTNRVVTLWYRPPEL 685
Query: 203 LVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYN 262
L+ + Y +DMW +GC++A M RK P G QL I + G+ + +
Sbjct: 684 LLGEREYGPEIDMWGVGCIMAEMWSRK-PLMQGRSEQHQLSLITDLCGSLNAEVWPGVTK 508
Query: 263 IELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHP 322
+EL + + G+ RK ER + L + E + +D LR D R+ A+ H
Sbjct: 507 LELYGKLDLPQGK-PRKVKERML----DLLKNKEGAELIDIFLRLDPGQRMNCDNALSHD 343
Query: 323 YFYT 326
+F+
Sbjct: 342 FFWV 331
>04138
Length = 800
Score = 86.7 bits (213), Expect = 1e-17, Method: Compositional matrix adjust.
Identities = 56/195 (28%), Positives = 101/195 (51%), Gaps = 6/195 (3%)
Frame = +1
Query: 144 LDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPG----QEYNVRVASRYFKG 199
L Y H I+HRD+K N++I + L+L D+GLA + Y RV + +++
Sbjct: 52 LYYIHRNKILHRDMKAANILITKQG-VLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRP 228
Query: 200 PELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLG--TEDLYDY 257
PELL+ + Y ++D W GC++A M + + P G +QL I ++ G T +++
Sbjct: 229 PELLLGDRNYSTAIDQWGAGCIMAEM-WTRNPIMQGTTEQNQLTLITQLCGSITPEVWPG 405
Query: 258 IDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTARE 317
+ + ++ + GR + R +RF + L P LD ++LL+ D R++A E
Sbjct: 406 VTQLSMYHQIKGALAAGRKNIIR-DRFA----RILKDPYGLDLFERLLKMDPSQRISADE 570
Query: 318 AMEHPYFYTVVKDQA 332
A+ H +F+ V+ ++
Sbjct: 571 ALNHDFFWVGVEPKS 615
>29581
Length = 1278
Score = 85.5 bits (210), Expect = 3e-17, Method: Compositional matrix adjust.
Identities = 69/255 (27%), Positives = 124/255 (48%), Gaps = 15/255 (5%)
Frame = -2
Query: 85 LENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTL----TDYDIRFYMYEI 140
L NLR NI+ L ++V + LV E+ D L + ++ ++ + ++
Sbjct: 1193 LLNLRHQ-NIVQLQEVVVGKSLDSLFLVMEYCEQ-DLASLLDNMPAPFSESQVKCIVLQL 1020
Query: 141 LKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFY-HPGQEYNVRVASRYFKG 199
LK L Y H I+HRD+K N+++ + +++ D+GLA Y P + +V + +++
Sbjct: 1019 LKGLRYLHEAFIIHRDLKVSNLLMT-DKGCVKIADFGLARNYGKPQKPMTPKVVTLWYRA 843
Query: 200 PELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYI- 258
PELL + + ++DMWS GC+L ++ K P G + Q+ I ++LGT + D I
Sbjct: 842 PELLFGSKTHSTAIDMWSAGCILGELLGHK-PLMPGRSDLQQIELIMELLGTPN--DTIW 672
Query: 259 ---------DKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDH 309
+++ ++ P +N++ RH+ W +S + L+ L Y
Sbjct: 671 PGFSQLPAFEQFTLKKQP-YNNL--RHTFP-W-----------LSESGIRLLNGLFMYHP 537
Query: 310 QSRLTAREAMEHPYF 324
Q R TA + +EH YF
Sbjct: 536 QKRATAEDCLEHSYF 492
>32000
Length = 644
Score = 85.1 bits (209), Expect = 4e-17, Method: Compositional matrix adjust.
Identities = 52/158 (32%), Positives = 81/158 (51%), Gaps = 3/158 (1%)
Frame = -1
Query: 170 KLRLIDWGLAE-FYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFR 228
K+++ D+GLA F P + Y V + +++ PE+L+ + Y +D+WSLGC+ M+ R
Sbjct: 575 KMKIADFGLARVFGLPVRTYTHEVITLWYRAPEILLGCRFYSVPVDIWSLGCIFVEMMTR 396
Query: 229 KEPFFHGHDNYDQLVRIAKVLGT--EDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVH 286
+ F G DQL RI + LGT E ++ + K P + + K E V
Sbjct: 395 RA-LFPGDSEIDQLYRIFRTLGTPDEKVWPGVSKL-----PDYKPTFPKWPLKNLETVVS 234
Query: 287 SENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYF 324
+S LD L ++L Y+ R++AR AM HPYF
Sbjct: 233 ------LSKVGLDLLKRMLTYNPNRRISARSAMRHPYF 138
>01756
Length = 1858
Score = 77.0 bits (188), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 66/269 (24%), Positives = 114/269 (42%), Gaps = 19/269 (7%)
Frame = -3
Query: 2 SGPVPSRARVYTDVNTHRPREYWDYESHVVEWGNQD-DYQLVRKLGRGKYSEVFEAINIT 60
S SR R D + P YE+ + ++D Y+ + K+G+G + EVF+A
Sbjct: 1835 STASASREREQKDSQRYSP-----YETLKFPFCDEDAKYEKLAKIGQGTFGEVFKARCKK 1671
Query: 61 NNEXXXXXXXXXXXXXXXXXXXXXLE----NLRGGPNIITLADIVKDPVSRTPA------ 110
+ E L N++ L +I +
Sbjct: 1670 TKQVVAMKKVLMDNEKEGFPITALREIKILQLLNHENVVDLIEICSTKATSANRYKSMFY 1491
Query: 111 LVFEHVNNTDFKQLYQTLTDY----DIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDH 166
LVFE + D L ++ +I+ M +++ L Y H I+HRD+K N++I
Sbjct: 1490 LVFEFCEH-DLAGLLSNMSVVFNLPEIKEVMKQLMNGLYYIHRNKILHRDMKAANILITK 1314
Query: 167 EHRKLRLIDWGLAEFYHPG----QEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCML 222
+ L+L D+GLA + Y RV + +++ PELL+ + Y ++D W GC++
Sbjct: 1313 QG-VLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRPPELLLGDRNYSTAIDQWGAGCIM 1137
Query: 223 ASMIFRKEPFFHGHDNYDQLVRIAKVLGT 251
A M + + P G +QL I ++ G+
Sbjct: 1136 AEM-WTRNPIMQGTTEQNQLTLITQLCGS 1053
>21079
Length = 878
Score = 76.3 bits (186), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 44/133 (33%), Positives = 74/133 (55%), Gaps = 5/133 (3%)
Frame = +1
Query: 92 PNIITLADIVKDPVSRTPALVFEHVNNTD-FKQLYQ---TLTDYDIRFYMYEILKALDYC 147
P ++ L D + P RT LV E V + F+++ + LT+ D ++ +I + Y
Sbjct: 4 PKLLMLWDAFEAP--RTMVLVMEFVGAGELFERVIRDDFVLTERDCVHFVRQICSGVGYM 177
Query: 148 HSMGIMHRDVKPHNVM-IDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDY 206
H+ I+H D+KP NV+ + ++++ID+GLA FY PG V + F PE +V+Y
Sbjct: 178 HTQSILHLDLKPENVLCVSDNSNQIKIIDFGLARFYKPGDSLQVLFGTPEFIAPE-VVNY 354
Query: 207 QMYDYSLDMWSLG 219
+++ DMWS+G
Sbjct: 355 DEINFTTDMWSIG 393
>15910
Length = 1361
Score = 70.1 bits (170), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 54/201 (26%), Positives = 91/201 (45%), Gaps = 2/201 (0%)
Frame = +2
Query: 129 TDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMID--HEHRKLRLIDWGLAEFYHPGQ 186
T+ D + +IL + Y H+ G++HRD+KP N++ + + KL+L D+GL+ P
Sbjct: 458 TEKDAARAISDILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLADFGLSRIIEPEV 637
Query: 187 EYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIA 246
+ + + + PE+L + Y S+DMWS+G + ++ EPFF ++
Sbjct: 638 QMSTVCGTPGYCAPEVLKGDK-YTPSVDMWSVGVIAYILLCGYEPFFAENEF-------- 790
Query: 247 KVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLR 306
++Y I K + D + W +S A D + KLL
Sbjct: 791 ------EMYRKIIKGEYKFDEEY-----------WSE---------ISENAKDVVRKLLV 892
Query: 307 YDHQSRLTAREAMEHPYFYTV 327
D + RLTA EA+ P+ V
Sbjct: 893 IDPKKRLTATEALRLPWVKGV 955
>23319
Length = 2235
Score = 68.6 bits (166), Expect = 4e-12, Method: Compositional matrix adjust.
Identities = 42/120 (35%), Positives = 60/120 (50%), Gaps = 2/120 (1%)
Frame = +3
Query: 207 QMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLG--TEDLYDYIDKYNIE 264
+MY S+DMWS GC+ A + P F G+D+ DQL RI K+LG TED + + +
Sbjct: 21 KMYSTSIDMWSAGCIFAELANAGRPLFPGNDDDDQLKRIFKLLGTPTEDQWPGMTQL--- 191
Query: 265 LDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYF 324
P + H W++ V N + D L LL R++A EA++HPYF
Sbjct: 192 --PNYRMFPMYHVTTTWQQVVPKLNS-----KGRDLLQCLLVCCPSDRMSADEALQHPYF 350
>26560
Length = 398
Score = 68.6 bits (166), Expect = 4e-12, Method: Compositional matrix adjust.
Identities = 36/106 (33%), Positives = 63/106 (59%)
Frame = -1
Query: 127 TLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQ 186
T+ ++RFY E++ L++ HS +++RD+KP N+++D E+ +R+ D GLA + +
Sbjct: 368 VFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLD-ENGHVRISDLGLACDFSKKR 192
Query: 187 EYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPF 232
+ V + + PE+L+ Q YD S D +S GCML ++ PF
Sbjct: 191 PH-ASVGTHGYMAPEVLMKGQSYDSSADWFSFGCMLYKLLKGHSPF 57
>00300
Length = 2318
Score = 62.4 bits (150), Expect = 3e-10, Method: Compositional matrix adjust.
Identities = 53/226 (23%), Positives = 104/226 (46%), Gaps = 18/226 (7%)
Frame = -1
Query: 39 YQLVRKLGRGKYSEVFEAINITNNEXXXXXXXXXXXXXXXXXXXXXLENLRGGPNIITLA 98
+Q K+G G++ +V+ A+N++ E L+ LR + I +
Sbjct: 1652 WQRGNKIGEGQFGKVYTAVNMSTGELMALKEMKFQPND--------LQQLREMCDEIKIF 1497
Query: 99 DIVKDP---------VSRTPALVF-EHVNNTDFKQLYQT-LTDYDIRFYMYEILKALDYC 147
+ ++ V + L+F E+ + ++ + L +Y IR Y EI+ A+++
Sbjct: 1496 EGIQHENLVKYYGVEVHKDEMLMFMEYCDTGTIEEAAKMGLPEYLIRRYTREIVLAVNHL 1317
Query: 148 HSMGIMHRDVKPHNVMIDHEHRKLRLIDWGL-----AEFYHPGQEYNVRVASRYFKGPEL 202
H I+HRD+K N+ + + ++L D+G + PG+ +N+ V + + PE+
Sbjct: 1316 HENSIVHRDIKGANIFLT-SNGHVKLGDFGCSVKLKSHTTMPGEFHNL-VGTTAYMAPEV 1143
Query: 203 LV--DYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIA 246
D Y + D+WSLGC++ M K P+ +NY + ++
Sbjct: 1142 FTQNDQGGYGRAADIWSLGCVVIEMATGKRPWHDLDNNYQIMYKVG 1005
>12721
Length = 821
Score = 61.6 bits (148), Expect = 5e-10, Method: Compositional matrix adjust.
Identities = 33/96 (34%), Positives = 57/96 (59%), Gaps = 1/96 (1%)
Frame = +1
Query: 140 ILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGL-AEFYHPGQEYNVRVASRYFK 198
LKAL + H+ G++HRD+K ++++ H+ K++L D+G A+ Q+ V + Y+
Sbjct: 400 CLKALAFLHANGVIHRDIKSDSILLSHDG-KVKLXDFGFCAQVTQDLQKRKSLVGTPYWM 576
Query: 199 GPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFH 234
PE++ Y +D+WSLG M+ MI + PFF+
Sbjct: 577 APEVISRLP-YGPEVDIWSLGIMVMEMIDAEPPFFN 681
>13212
Length = 1067
Score = 61.2 bits (147), Expect = 6e-10, Method: Compositional matrix adjust.
Identities = 53/208 (25%), Positives = 89/208 (42%), Gaps = 7/208 (3%)
Frame = -1
Query: 124 LYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVM--IDHEHRKLRLIDWGL-AE 180
L + +T+ I + +E+ ALD+ H ++HRD+K NV+ ID E ++L D+G+ A+
Sbjct: 1001 LEKPMTEAQICYVCHEMCMALDFLHRHHVIHRDIKAGNVLLTIDGE---VKLADFGVSAK 831
Query: 181 FYHPGQEYNVRVASRYFKGPELLVDYQM----YDYSLDMWSLGCMLASMIFRKEPFFHGH 236
Q+ + + + Y+ PE+++ + YD+ D+WSLG L + P H
Sbjct: 830 NTQTQQKRDTFIGTPYWMAPEVVLCETLKDTPYDFKADIWSLGVTLIEFAQIEPPNKEMH 651
Query: 237 DNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPE 296
L++I K +D K+W +
Sbjct: 650 -PMRVLIKIHK----------------------SDPPTLEKPKKWTKLFK---------- 570
Query: 297 ALDFLDKLLRYDHQSRLTAREAMEHPYF 324
DF+ K L D R TA E +EHP+
Sbjct: 569 --DFIAKCLVKDPNLRPTAAELLEHPFM 492
>12786
Length = 460
Score = 61.2 bits (147), Expect = 7e-10, Method: Compositional matrix adjust.
Identities = 43/143 (30%), Positives = 72/143 (50%), Gaps = 22/143 (15%)
Frame = -3
Query: 126 QTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPG 185
Q L I+FY E+L+A+ H+ G++H D+KP N M+ + L+LID+G+A
Sbjct: 425 QGLDRMMIKFYWREMLRAVKALHNEGVIHSDLKPANFMLVAGN--LKLIDFGIANTLQQD 252
Query: 186 QEY---NVRVASRYFKGPELLV-------DYQMYD--------YSL----DMWSLGCMLA 223
+ + RV + + PE ++ D M + Y + D+WSLGC+L
Sbjct: 251 KTSVLKDSRVGTPSYMSPEAIMAACDDSADDSMEEDGHRTKPKYKVGVRSDVWSLGCILY 72
Query: 224 SMIFRKEPFFHGHDNYDQLVRIA 246
+M++ + PF H +N +L I
Sbjct: 71 NMVYGRTPFQHIKNNMGKLQAIT 3
>01392
Length = 1806
Score = 60.5 bits (145), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 56/211 (26%), Positives = 88/211 (41%), Gaps = 12/211 (5%)
Frame = -1
Query: 128 LTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDH--EHRKLRLIDWGLAEFYH-- 183
L + + + I +ALD+ HS GI HRD+KP N++ +H + +++ D+ LA
Sbjct: 1800 LCEREASLVVRHIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGISCD 1621
Query: 184 ----PGQEYNVRVASRYFKGPEL----LVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHG 235
E V S + PE+ + D YD D+WSLG +L M+ PF
Sbjct: 1620 GDGTKTPELLTPVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILYIMLCGYPPF--- 1450
Query: 236 HDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSP 295
Y Q E +D D FN I H + S+ +S
Sbjct: 1449 ---YGQCGEDCGWNRGEACHDCQDML-------FNSIQDGHYK------FPSQEWTSISS 1318
Query: 296 EALDFLDKLLRYDHQSRLTAREAMEHPYFYT 326
A D + LL + + R +A + ++HP+ T
Sbjct: 1317 SAKDLIRHLLVREPRKRYSAADVLKHPWICT 1225
>30755
Length = 1137
Score = 60.5 bits (145), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 39/125 (31%), Positives = 66/125 (52%), Gaps = 2/125 (1%)
Frame = +2
Query: 126 QTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLA-EFYHP 184
+ T+ RFY EI+ AL Y HS GI++RD+K N+++D + +++ D+GL E
Sbjct: 17 RIFTEERTRFYGAEIISALGYLHSQGIIYRDLKLENLLLDKDGH-IKVADFGLCKEDITY 193
Query: 185 GQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFH-GHDNYDQLV 243
G+ + + PE+L D Y ++D W G ++ MI + PF++ HD L+
Sbjct: 194 GRTTKTFCGTPEYLAPEVLDDND-YGRAVDWWGTGVVMYEMICGRLPFYNRDHDVLFTLI 370
Query: 244 RIAKV 248
+ V
Sbjct: 371 LVEDV 385
>28638
Length = 1458
Score = 60.1 bits (144), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 28/77 (36%), Positives = 49/77 (63%), Gaps = 1/77 (1%)
Frame = -1
Query: 150 MGIMHRDVKPHNVMIDHEHRK-LRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQM 208
M I+H D+KP N+++ + R ++++D+G + GQ + SR+++ PE+L+
Sbjct: 774 MNIIHCDLKPENILLCNPKRSAIKIVDFGSS--CQLGQRIYQYIQSRFYRSPEVLLGVP- 604
Query: 209 YDYSLDMWSLGCMLASM 225
YD ++DMWSLGC+L M
Sbjct: 603 YDLAIDMWSLGCILVEM 553
Score = 32.7 bits (73), Expect = 0.25, Method: Compositional matrix adjust.
Identities = 32/141 (22%), Positives = 60/141 (42%), Gaps = 32/141 (22%)
Frame = -2
Query: 216 WSLGCMLASMIFRK----EPFFHGHDNYDQLVRIAKVLG------------TEDLYDYI- 258
W L C ++ + + P F G + +DQ+++I +VLG T +D +
Sbjct: 596 WPLTCGXWAVYWWRCTXGNPLFAGSNEFDQMMKIVEVLGVPPRHILDQAQKTRKYFDLLP 417
Query: 259 ------------DKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLR 306
KY + +++LG R + E H V+ + L F D +LR
Sbjct: 416 DGTYAPKKPRDNKKYKSPSSRKLHEVLGAEKGGPGGRRM-GEPGHTVA-DYLKFKDLILR 243
Query: 307 ---YDHQSRLTAREAMEHPYF 324
+D ++R++ A++H +F
Sbjct: 242 MLDFDPKTRISPYYALQHNFF 180
>01966
Length = 1735
Score = 59.7 bits (143), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 37/136 (27%), Positives = 72/136 (52%), Gaps = 7/136 (5%)
Frame = -1
Query: 93 NIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQ------TLTDYDIRFYMYEILKALDY 146
NI+ L D++ + LVFE ++ D K L ++ Y+++I+ +++
Sbjct: 1531 NIVCLEDVIME--DERLFLVFEFLS-MDLKMYIDKFPEGVVLDRRLVKSYVFQIVTGINF 1361
Query: 147 CHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAE-FYHPGQEYNVRVASRYFKGPELLVD 205
CH I+HRD+KP N++I+H +++ D+G+A F P + Y V + +++ PE+L+
Sbjct: 1360 CHQRRIVHRDLKPQNLLINHTG-AIKIADFGMARTFALPVRAYTHEVVTLWYRAPEILMG 1184
Query: 206 YQMYDYSLDMWSLGCM 221
Q + W+ G +
Sbjct: 1183 PQ---STPPXWTCGAL 1145
Score = 57.0 bits (136), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 32/119 (26%), Positives = 58/119 (48%)
Frame = -3
Query: 209 YDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPR 268
Y +D+WS+G + A M+ R P F G DQL +I +++GT + + + + P
Sbjct: 1175 YSTPVDVWSIGTIFADMLIRT-PIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKL---PA 1008
Query: 269 FNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTV 327
FN + W+ SE + LD +++ L+ D R++ ++ ++H YF V
Sbjct: 1007 FNGMF-----PLWKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYFLNV 846
>14420
Length = 528
Score = 57.4 bits (137), Expect = 9e-09, Method: Compositional matrix adjust.
Identities = 30/97 (30%), Positives = 55/97 (56%), Gaps = 1/97 (1%)
Frame = +2
Query: 139 EILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQ-EYNVRVASRYF 197
E L+AL++ H ++HRD+K N+++ + ++L D+G P Q + + V + Y+
Sbjct: 221 ECLQALEFLHENQVIHRDIKSDNILLGMDG-SVKLTDFGFCAQLSPEQSKRSTMVGTPYW 397
Query: 198 KGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFH 234
PE++ Q Y ++D+WSLG M MI + P+ +
Sbjct: 398 MAPEVVTRKQ-YGPTVDIWSLGVMCIEMIEGEPPYLN 505
>27405
Length = 532
Score = 57.0 bits (136), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 35/128 (27%), Positives = 67/128 (52%), Gaps = 3/128 (2%)
Frame = -3
Query: 90 GGPNIITLADIVKDPVSRTPALVFEHVNNTDFK---QLYQTLTDYDIRFYMYEILKALDY 146
G P I+ + + P + + +N D + T+ ++RFY E++ L++
Sbjct: 380 GSPFIVCMTYAFQTP--EKLCFILDLMNGGDLHYHLSQHGVFTEKEVRFYAAEVMLGLEH 207
Query: 147 CHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDY 206
HS +++RD+KP N+++D E+ +R+ D GLA + ++ + V + + PE+L+
Sbjct: 206 MHSRFVVYRDLKPANILLD-ENGHVRISDLGLACDFSK-KKPHASVGTHGYMAPEVLMKG 33
Query: 207 QMYDYSLD 214
Q YD S D
Sbjct: 32 QAYDSSAD 9
>18921
Length = 697
Score = 56.6 bits (135), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 34/110 (30%), Positives = 57/110 (51%), Gaps = 1/110 (0%)
Frame = +2
Query: 126 QTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLA-EFYHP 184
+TL + +I +Y LK L Y HS +HRD+K N+++++E +L D+G+A +
Sbjct: 302 KTLVEREIATILYYTLKGLXYLHSRRKIHRDIKAGNILLNNEGHA-KLADFGVAGQLTDT 478
Query: 185 GQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFH 234
+ N + + Y+ PE++ + YD D+WSLG M K P
Sbjct: 479 MAKRNTVIGTPYWMAPEVIQEIG-YDCVADIWSLGITALEMAEGKPPVME 625
>31885
Length = 529
Score = 55.5 bits (132), Expect = 4e-08, Method: Compositional matrix adjust.
Identities = 29/104 (27%), Positives = 55/104 (52%), Gaps = 4/104 (3%)
Frame = -2
Query: 133 IRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRV 192
++FY+ ++ LDY S I+HRD+KP N+++D E + D+ +A +
Sbjct: 366 VKFYLCQLALVLDYLRSQKIVHRDIKPDNILLD-EQGHCHVTDFNIATQLEDDELATSTS 190
Query: 193 ASRYFKGPEL----LVDYQMYDYSLDMWSLGCMLASMIFRKEPF 232
+R + PE+ + + + Y + +D WSLG L ++ ++ PF
Sbjct: 189 GTRPYMAPEVYGVAINERRGYGFPVDWWSLGVSLFELLKKRRPF 58
>03294
Length = 1684
Score = 55.1 bits (131), Expect = 4e-08, Method: Compositional matrix adjust.
Identities = 31/117 (26%), Positives = 58/117 (49%)
Frame = -1
Query: 211 YSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFN 270
+ +D+WS+G + A M+ R P F G DQL +I +++GT + + + + P FN
Sbjct: 1678 HPVDVWSIGTIFADMLIRT-PIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKL---PAFN 1511
Query: 271 DILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTV 327
+ W+ SE + LD +++ L+ D R++ ++ ++H YF V
Sbjct: 1510 GMF-----PLWKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYFLNV 1355
>19761
Length = 473
Score = 55.1 bits (131), Expect = 5e-08, Method: Compositional matrix adjust.
Identities = 38/125 (30%), Positives = 62/125 (49%), Gaps = 3/125 (2%)
Frame = -3
Query: 133 IRFYMYEILKALDYCHSMG--IMHRDVKPHNVMIDHEHRKLRLIDWGLA-EFYHPGQEYN 189
I ++ + AL+Y H+ I+HRD+KP N+ + E +RL D GLA + P
Sbjct: 417 IVCWLMQTASALNYMHTHTPVILHRDLKPQNIYVT-EKGDVRLGDLGLARKLTGPADFAT 241
Query: 190 VRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVL 249
+V + + PE+L Q Y+ D+WSLGC+ + +K G D + + +V+
Sbjct: 240 SQVGTIMYLSPEIL-SQQPYNSKSDIWSLGCVFYDITGKK-----GSDEMGVMFLLVQVM 79
Query: 250 GTEDL 254
G L
Sbjct: 78 GGRKL 64
>26711
Length = 405
Score = 55.1 bits (131), Expect = 5e-08, Method: Compositional matrix adjust.
Identities = 28/95 (29%), Positives = 53/95 (55%), Gaps = 1/95 (1%)
Frame = -2
Query: 139 EILKALDYCHSMGIMHRDVKPHNVMIDHEH-RKLRLIDWGLAEFYHPGQEYNVRVASRYF 197
++L L + H+ G++H D+KP N+++ + ++LID+GLA +P QE + + F
Sbjct: 392 QVLDILQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARKLYPPQETFLNHGTPGF 213
Query: 198 KGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPF 232
PE L D + + D+W +G + ++ + PF
Sbjct: 212 TSPEAL-DVKPISTASDVWGVGVLAYILLSGQSPF 111
>18484
Length = 635
Score = 54.7 bits (130), Expect = 6e-08, Method: Compositional matrix adjust.
Identities = 35/104 (33%), Positives = 55/104 (52%), Gaps = 6/104 (5%)
Frame = +1
Query: 135 FYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVAS 194
FY EI L + H GI++RD+K NVM+D E +++ D+G+ + G +
Sbjct: 55 FYAAEIAVGLFFLHDQGIIYRDLKLDNVMLDSEGH-IKIADFGMCKEGMTGD-----ATT 216
Query: 195 RYFKG------PELLVDYQMYDYSLDMWSLGCMLASMIFRKEPF 232
R F G PE+++ YQ Y S+D W+ G +L M+ + PF
Sbjct: 217 RTFCGTPDYIAPEIVL-YQPYSKSVDWWAYGVLLFEMLAGQPPF 345
>09606
Length = 1300
Score = 54.3 bits (129), Expect = 9e-08, Method: Compositional matrix adjust.
Identities = 54/222 (24%), Positives = 91/222 (40%), Gaps = 25/222 (11%)
Frame = -3
Query: 128 LTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAE------- 180
L + IR + ++ L Y HS+GI+ D++P V++D L+ D+GL++
Sbjct: 842 LPETSIRDFGIHLVTGLHYIHSLGILFHDLRPSKVLLD-TSGVLKFADFGLSKVEGENLE 666
Query: 181 -----FYHPGQEYNVRVASRYFK-----------GPELLVDYQMYDYSL--DMWSLGCML 222
F G ++N++ A K PE+ +Q + S+ D+W+LGC+
Sbjct: 665 ELFFKFAEAGDQWNIQSAEEMMKQVPTSGSPTYMAPEV---FQGAEPSIMSDLWALGCVF 495
Query: 223 ASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWE 282
M F P F G + YD + KVL E + + P
Sbjct: 494 YEM-FSGHPPFLG-ETYD--ITKDKVLNKEFPLPKVKGSRLSAKP--------------- 372
Query: 283 RFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYF 324
SPE L+ L+ LL+ D RL+ ++H ++
Sbjct: 371 -----------SPEFLNLLESLLQKDSTRRLSWASLVKHAFW 279
>19094
Length = 898
Score = 53.9 bits (128), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 32/101 (31%), Positives = 55/101 (54%), Gaps = 1/101 (0%)
Frame = +1
Query: 126 QTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLA-EFYHP 184
+TL + +I +Y LK L Y HS +HRD+K N+++++E +L D+G+A +
Sbjct: 43 KTLVEREIATILYYTLKGL*YLHSRRKIHRDIKAGNILLNNEGHA-KLADFGVAGQLTDT 219
Query: 185 GQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASM 225
+ N + + Y+ PE++ + YD D+WSLG M
Sbjct: 220 MAKRNTVIGTPYWMAPEVIQEIG-YDCVADIWSLGITALEM 339
>18287
Length = 678
Score = 53.9 bits (128), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 35/119 (29%), Positives = 63/119 (52%), Gaps = 3/119 (2%)
Frame = -3
Query: 209 YDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGT---EDLYDYIDKYNIEL 265
YDYS+D+WS+GC+ A ++ R+ F QL I ++GT ED+ +
Sbjct: 673 YDYSIDIWSVGCIFAELLSRRI-LFQAQGPVQQLDMIINLVGTPRPEDMERACEGAR--- 506
Query: 266 DPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYF 324
N IL + R++ +++ + H + EA+ L ++L + ++R++A EA+ HPY
Sbjct: 505 ----NHILNQPFRRQNLLTLYNLSPH-ATHEAVRLLTRMLILNPKNRISAEEALSHPYL 344
>13592
Length = 980
Score = 53.1 bits (126), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 63/296 (21%), Positives = 114/296 (38%), Gaps = 16/296 (5%)
Frame = +2
Query: 44 KLGRGKYSEVFEAINITNNEXXXXXXXXXX--XXXXXXXXXXXLENLRGGPNIITLADIV 101
K+G+G++ +V+ A+N E L+ L G I ++V
Sbjct: 5 KIGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETRALKNVAEELKILEG----IKHKNLV 172
Query: 102 K---DPVSRTPALVFEHVNNT----DFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMH 154
+ V R L+F + + +L L + R + ++L + H GI+H
Sbjct: 173 RYYGIEVHREELLIFMELCSEGTLESLVELTGGLPEALSRRFTAQLLSGVAELHKHGIVH 352
Query: 155 RDVKPHNVMIDHEHRKLRLIDWGLAEFYH-----PGQEYNVRVASRYFKGPELLVDYQMY 209
RD+K N+ + L+L D+G A PG E V ++ + PE+
Sbjct: 353 RDIKTANIFLVDGSNSLKLGDFGSAVKIQAHTTVPG-ELQGYVGTQAYMAPEVFTKTNSD 529
Query: 210 DYS--LDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDP 267
+ D+WS+GC++ M K P+ N+ + ++ +G + P
Sbjct: 530 GHGRLADIWSVGCVVVEMASGKRPWAQFDSNFQIMFKVG--MGEK--------------P 661
Query: 268 RFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPY 323
+ + L S E DF+D L++D + RL+A E +E +
Sbjct: 662 QAPESL--------------------SQEGHDFIDHCLQHDPKQRLSAIELLEQNF 769
>18401
Length = 463
Score = 50.4 bits (119), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 35/143 (24%), Positives = 75/143 (52%), Gaps = 10/143 (6%)
Frame = -3
Query: 192 VASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGT 251
V++R+++ PE++++ + + D+WS+GC++ ++ F HDN + L + ++LG+
Sbjct: 449 VSTRHYRAPEVILELG-WSHPCDVWSVGCIMFE-LYTGYTLFQTHDNKEHLAMMERILGS 276
Query: 252 EDLYDYIDK-------YNIELDPRFNDILGRHSRKRWE---RFVHSENQHLVSPEALDFL 301
Y K ++ LD + R+ R+ + R+V + ++ + D +
Sbjct: 275 LP-YRMAKKTKKQKYFHHGRLDVPERSSMARYVRENTKPLLRYV-KDRENKDHQQLFDLM 102
Query: 302 DKLLRYDHQSRLTAREAMEHPYF 324
KLL Y+ SR + +A++HP+F
Sbjct: 101 KKLLAYEASSRYSLLQALQHPFF 33
>03240
Length = 1683
Score = 49.7 bits (117), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 36/145 (24%), Positives = 57/145 (39%), Gaps = 45/145 (31%)
Frame = -3
Query: 134 RFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGL--------------- 178
RFY+ E+++A++ H MG +HRD+KP N++ID ++L D+GL
Sbjct: 982 RFYVAELVQAIESVHRMGFIHRDIKPDNILIDRNGH-IKLTDFGLCTGFRWTHNSKYYQR 806
Query: 179 ---------------------AEFYHPGQEYNVR---------VASRYFKGPELLVDYQM 208
E P + R V + + PE+L
Sbjct: 805 DGTHARQDSMEVKCQLDEQCQCEILKPLERRRKREQRCLAHSLVGTPNYIAPEVLSRLGG 626
Query: 209 YDYSLDMWSLGCMLASMIFRKEPFF 233
Y D WS+G +L M+ PF+
Sbjct: 625 YTSVCDWWSVGVILFEMLVGHPPFY 551
>21433
Length = 590
Score = 48.9 bits (115), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 43/172 (25%), Positives = 76/172 (44%)
Frame = +2
Query: 136 YMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASR 195
Y+Y++ AL+YCH ++HRD+KP N+++ L++ D+G + + P +
Sbjct: 182 YIYQLSSALEYCHYRKVIHRDIKPENLLLG-LKGDLKIADFGWS-VHAPSSRRTTMCGTL 355
Query: 196 YFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLY 255
+ PE +V+ + +D ++D+WSLG + Y+ LV GT L
Sbjct: 356 DYLPPE-MVEGKTHDENVDLWSLGVLC----------------YEFLV------GTPPLR 466
Query: 256 DYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRY 307
+ PR+ S + +V+P A D + KLLR+
Sbjct: 467 PSPTRPPTPASPRWT----------------SGSPSIVTPGARDLISKLLRH 574
>13078
Length = 773
Score = 48.5 bits (114), Expect = 5e-06, Method: Compositional matrix adjust.
Identities = 37/126 (29%), Positives = 61/126 (48%), Gaps = 14/126 (11%)
Frame = -1
Query: 213 LDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDK-------YNIEL 265
D+WS+GC++ ++ F HDN + L + ++LG+ Y K Y+ L
Sbjct: 734 CDVWSIGCIMFE-LYTGYTLFQTHDNKEHLAMMERILGSLP-YRMAKKTKKQKYFYHGRL 561
Query: 266 DPRFNDILGRHSR---KRWERFV----HSENQHLVSPEALDFLDKLLRYDHQSRLTAREA 318
D GR+ R K R+V + ++Q L D +DK+L Y+ +R + R+A
Sbjct: 560 DWDEKSSAGRYVRDNVKPLRRYVKDPDNEDHQQL-----FDLMDKMLSYEVSTRYSLRQA 396
Query: 319 MEHPYF 324
M HP+F
Sbjct: 395 MRHPFF 378
>31489
Length = 329
Score = 47.4 bits (111), Expect = 9e-06, Method: Compositional matrix adjust.
Identities = 27/77 (35%), Positives = 49/77 (63%), Gaps = 6/77 (7%)
Frame = +3
Query: 93 NIITLADIVKDPVS----RTPALVFEHVNNTDFKQLY--QTLTDYDIRFYMYEILKALDY 146
NII++ +I+K S + +VF+ + + + +Y Q LT+ IR+++Y+IL+ L Y
Sbjct: 33 NIISIREILKPKDSYHDFKDIHVVFDLMESDLHRIIYSDQPLTEEHIRYFLYQILRGLKY 212
Query: 147 CHSMGIMHRDVKPHNVM 163
HS ++HRD+KP N++
Sbjct: 213 IHSANVVHRDLKPSNLL 263
>13066
Length = 551
Score = 46.6 bits (109), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 27/90 (30%), Positives = 45/90 (50%), Gaps = 4/90 (4%)
Frame = +3
Query: 134 RFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGL--AEFYHPGQEYNVR 191
+ + Y++ AL+Y HS + HRD+K N+++ H ++L D+G A G++Y R
Sbjct: 285 KIWFYQMTTALNYLHSYDVAHRDLKCENILLS-SHFNVKLADFGFACACITESGEKYMSR 461
Query: 192 --VASRYFKGPELLVDYQMYDYSLDMWSLG 219
S + PE++ D WSLG
Sbjct: 462 TYCGSAAYAAPEIVYGAPYAPKVADAWSLG 551
>04852
Length = 1462
Score = 46.6 bits (109), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 28/90 (31%), Positives = 46/90 (51%), Gaps = 3/90 (3%)
Frame = +1
Query: 136 YMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASR 195
Y ++I + +++ S +HRD+ NV++ EH L++ D+GL+ G Y R R
Sbjct: 340 YAFQIARGMEFLASRKCIHRDLAARNVLVTEEH-VLKIADFGLS---RTGDYYKKRSGGR 507
Query: 196 Y---FKGPELLVDYQMYDYSLDMWSLGCML 222
+ PE L D + Y D+WS G +L
Sbjct: 508 LPVKWMAPEALFDMR-YTTKSDVWSFGVVL 594
>07940
Length = 1336
Score = 45.8 bits (107), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 29/104 (27%), Positives = 50/104 (48%), Gaps = 3/104 (2%)
Frame = -3
Query: 122 KQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEF 181
+ + + LT D+ Y Y++ + ++Y S +HRD+ NV++ E+ L++ D+GL
Sbjct: 374 QDMLKMLTPKDLISYAYQVARGMEYLASKQCIHRDLAARNVLVAEEY-VLKIADFGLTRN 198
Query: 182 YHPGQEYNVRVASRY---FKGPELLVDYQMYDYSLDMWSLGCML 222
Y R + PE L D + Y D+WS G +L
Sbjct: 197 LQQFDYYRKTTDGRLPVKWMAPEALFDRK-YTSKSDVWSYGVLL 69
>11185
Length = 473
Score = 44.7 bits (104), Expect = 7e-05, Method: Compositional matrix adjust.
Identities = 31/120 (25%), Positives = 55/120 (45%), Gaps = 25/120 (20%)
Frame = +1
Query: 132 DIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAE----------- 180
IR + ++ L Y HS+GI+ D++P V++D L+ D+GL++
Sbjct: 4 SIRDFGIHLVTGLHYIHSLGILFHDLRPSKVLLDTSGV-LKFADFGLSKVEGENLEELFF 180
Query: 181 -FYHPGQEYNVRVASRYFK-----------GPELLVDYQMYDYSL--DMWSLGCMLASMI 226
F G ++N++ A K PE+ +Q + S+ D+W+LGC+ M
Sbjct: 181 KFAEAGDQWNIQSAEEMMKQVPTSGSPTYMAPEV---FQGAEPSIMSDLWALGCVFYEMF 351
>00715
Length = 1788
Score = 43.9 bits (102), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 38/149 (25%), Positives = 63/149 (42%), Gaps = 27/149 (18%)
Frame = +1
Query: 111 LVFEHVNNTDFKQL---YQTLTDYDIRFYM-YEILKALDYCHSMGIMHRDVKPHNVMIDH 166
L E+V + + + +Q D +R + ++ + L Y HS+ I+H D+KP N ++
Sbjct: 166 LAMEYVGPLNLQTILNDHQQDIDSSMRLSLALQMARGLHYLHSINIVHLDLKPANCLLTR 345
Query: 167 EHRKLRLIDWGLAEFYHP-----------------------GQEYNVRVASRYFKGPELL 203
+ KLR+ D+G P G N + ++ PELL
Sbjct: 346 D-LKLRIADFGCCHQLTPTGLDMGEREGGMAGNELELTPVQGAWKNELAGTLAYRAPELL 522
Query: 204 VDYQMYDYSLDMWSLGCMLASMIFRKEPF 232
Q S D++SLG L M R+ P+
Sbjct: 523 KGLQPSVRS-DVYSLGITLWQMCTRQGPY 606
>17975
Length = 449
Score = 42.0 bits (97), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 16/44 (36%), Positives = 30/44 (68%)
Frame = +3
Query: 136 YMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLA 179
Y +I++A+ YCH + ++HRD+KP NV+ + ++L D+G +
Sbjct: 282 YFRQIVEAISYCHKLHVVHRDLKPENVVFFEKPGLVKLTDFGFS 413
>37602
Length = 804
Score = 40.8 bits (94), Expect = 9e-04, Method: Compositional matrix adjust.
Identities = 26/90 (28%), Positives = 40/90 (44%), Gaps = 3/90 (3%)
Frame = -1
Query: 111 LVFEHVNNTDFKQLYQT---LTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHE 167
+ E+ + +Y LT+ I F E LK L Y H G MHRD+K N+++ E
Sbjct: 288 IAMEYCGGGSMQDIYHVTGPLTEPQIAFVCRETLKGLHYLHRRGKMHRDIKGANILLTEE 109
Query: 168 HRKLRLIDWGLAEFYHPGQEYNVRVASRYF 197
D LA+F+ ++ V + F
Sbjct: 108 G------DVKLADFWRVSSNHSHNVQKKVF 37
>14116
Length = 1017
Score = 40.8 bits (94), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 27/105 (25%), Positives = 51/105 (48%), Gaps = 5/105 (4%)
Frame = -1
Query: 129 TDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLA-----EFYH 183
T D+ Y +I + +DY + +HRD+ N M+D E +++ D+GLA + Y+
Sbjct: 327 TIKDLIMYGVDIARGMDYLAGLKFVHRDLAARNCMLD-EDFHVKVADFGLARDIYEKEYY 151
Query: 184 PGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFR 228
+ ++ ++ L + YD D+WS G +L ++ R
Sbjct: 150 SSENKKAKLPVKWMALESL--EKGNYDSKTDVWSYGVVLWELLTR 22
>01718
Length = 959
Score = 40.0 bits (92), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 49/218 (22%), Positives = 90/218 (41%), Gaps = 9/218 (4%)
Frame = +3
Query: 20 PREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEXXXXXXXXXXXXXXXX 79
P+ H V + D + K+G G +SEVF+ + +
Sbjct: 96 PKSSCQALRHAVSALTRLDDFICEKIGAGFFSEVFKVTHRITGQVMALKMNTMTSNRHNM 275
Query: 80 XXXXXLENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTD---YDIRFY 136
L N NI+ + + AL E++ + + +QL + + + R
Sbjct: 276 LREVQLLNRLQHANILRFMGVCVHE-GQLHALT-EYIPSGNLEQLLEKKDEELPWTQRIQ 449
Query: 137 M-YEILKALDYCHSMGIMHRDVKPHNVMI---DHEHRKLRLIDWGLA-EFYHP-GQEYNV 190
+ + + LDY HS +HRD+ N++I D+ + D+GLA + P +E
Sbjct: 450 LTLGLARGLDYLHSTRFIHRDLTSKNILIRREDNHGYHAVIADFGLATKIPDPLDKEKLP 629
Query: 191 RVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFR 228
V S Y+ PE+L + Y+ D++S+G ++ + R
Sbjct: 630 TVGSPYWMAPEVL-NGHFYNERADLFSVGIIMCEITAR 740
>01106
Length = 878
Score = 38.9 bits (89), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 38/163 (23%), Positives = 68/163 (41%), Gaps = 18/163 (11%)
Frame = +3
Query: 20 PREYWDYESHVVEWGN--QDDYQLVRKLGRGKYSEV----------FEAINITNNEXXXX 67
PR+Y H V+ G+ Y ++RKLG G +S V F A+ + +
Sbjct: 261 PRDYCKGGYHPVKNGDLFNGRYHVIRKLGWGHFSTVWLCWDLTCKRFVALKVVKSAQHYT 440
Query: 68 XXXXXXXXXXXXXXXXXLENLRGGPNIITLADIVKDPVSRT-PALVFEHVNNTDFKQL-- 124
+ + + L D V+ T A+VFE + K +
Sbjct: 441 ETALDEVKLLKCVRESDVADPARAKCVQLLDDFKISGVNGTHVAMVFEVLGYNLLKLIIR 620
Query: 125 --YQTLTDYDIRFYMYEILKALDYCHSMG-IMHRDVKPHNVMI 164
YQ + ++++ + ++L+ L Y H+ I+H D+KP N++I
Sbjct: 621 SNYQGIPIHNVKLIIRQVLEGLSYMHAKCRIIHTDIKPENILI 749
>26009
Length = 886
Score = 38.9 bits (89), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 14/33 (42%), Positives = 24/33 (72%)
Frame = +3
Query: 132 DIRFYMYEILKALDYCHSMGIMHRDVKPHNVMI 164
+ + M +++ ALD+ HS ++HRD+KP NV+I
Sbjct: 714 EAKSVMKQLVSALDFMHSKQLVHRDIKPENVLI 812
>05084
Length = 1324
Score = 38.1 bits (87), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 26/92 (28%), Positives = 40/92 (43%), Gaps = 2/92 (2%)
Frame = +2
Query: 235 GHDNYDQLVRIAKVLGTEDLYDYIDKYNI-ELDPRFNDI-LGRHSRKRWERFVHSENQHL 292
G DQLV I KVLGT + I E++P +++ + W +
Sbjct: 8 GDSGVDQLVEIIKVLGTP------TREQIREMNPNYSEFKFPQIKAHPWTKVFRPRT--- 160
Query: 293 VSPEALDFLDKLLRYDHQSRLTAREAMEHPYF 324
PEA+ + +LL Y +R+ EA H +F
Sbjct: 161 -PPEAIQLVSRLLEYTPSARIQPMEACAHAFF 253
>00392
Length = 668
Score = 38.1 bits (87), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 25/93 (26%), Positives = 51/93 (54%), Gaps = 3/93 (3%)
Frame = +3
Query: 133 IRFYMYEILKALDYCHSMG--IMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNV 190
++ + ++LK L + H+ ++HRD+K N+ I +++ D GLA + +V
Sbjct: 252 LKNWCRQVLKGLYFLHTRTPPVIHRDLKCDNIFITGPTGSVKIGDLGLATLKNQSFAKSV 431
Query: 191 RVASRYFKGPELLVDYQMYDYSLDMWSLG-CML 222
+ + F PE+ ++ YD ++D+++ G CML
Sbjct: 432 -IGTPEFMAPEMYEEH--YDEAVDVYAFGMCML 521
>06358
Length = 1517
Score = 38.1 bits (87), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 48/176 (27%), Positives = 84/176 (47%), Gaps = 31/176 (17%)
Frame = +3
Query: 123 QLYQTLTDYDIRFYMYEILKALDYCHS-MGIMHRDVKPHNVMIDHEHRKLRLIDWGLA-- 179
Q YQ L D +I+ + ++ +AL + H+ +MHR+V P +M+ +L W LA
Sbjct: 339 QDYQ-LYDVEIKHGLLQVTEALGFLHNDAKMMHRNVCPEAIMLT------KLGSWKLAGY 497
Query: 180 EFY------------HPGQEYNVRVASRY-----FKGPELLVDYQMYDYSLDMWSLGCML 222
EF +P E+ +A F PE ++ Q S DM+SLG ++
Sbjct: 498 EFCVRSSDPQSTDPSYPFYEWRSDIAPVTQPHLDFMAPEYVLTMQCGTGS-DMFSLGLLV 674
Query: 223 ASMIFRKEPFFHGH-------DNYDQL--VRIAKVLGT--EDLYDYIDKYNIELDP 267
S+ + +P F + N ++L +R++ +LG EDL D++ K + ++P
Sbjct: 675 YSVFAKGKPLFECNGELSAFKSNAEELRHMRVS-LLGVVPEDLRDHV-KLLLNIEP 836
>21800
Length = 855
Score = 37.0 bits (84), Expect = 0.014, Method: Compositional matrix adjust.
Identities = 24/86 (27%), Positives = 45/86 (52%), Gaps = 10/86 (11%)
Frame = +2
Query: 110 ALVFEHVNNTDFKQL----YQTLTDYDIRFYMYEILKALDYCHS-MGIMHRDVKPHNVMI 164
+VFE + K + YQ + ++++ + ++L+ L+Y H+ I+H D+KP N++I
Sbjct: 557 CMVFEVLGYNLLKLIIRSNYQGIPVHNVKLIIRQVLEGLNYLHAKCNIIHTDIKPENILI 736
Query: 165 ---DHEHRKLRL--IDWGLAEFYHPG 185
D+ RKL + +W PG
Sbjct: 737 CVDDNYIRKLAVDAFEWQRLGLKLPG 814
>32359
Length = 928
Score = 28.5 bits (62), Expect(2) = 0.023, Method: Compositional matrix adjust.
Identities = 9/17 (52%), Positives = 14/17 (82%)
Frame = -3
Query: 151 GIMHRDVKPHNVMIDHE 167
G+ HRD+KP N+++D E
Sbjct: 65 GVCHRDIKPQNLLLDPE 15
Score = 26.6 bits (57), Expect(2) = 0.023, Method: Compositional matrix adjust.
Identities = 15/49 (30%), Positives = 26/49 (53%), Gaps = 6/49 (12%)
Frame = -1
Query: 111 LVFEHVNNTDFK------QLYQTLTDYDIRFYMYEILKALDYCHSMGIM 153
LV E+V T ++ + QT+ I+ YMY++ ++L Y HS +
Sbjct: 202 LVLEYVPETVYRVARHYSKSKQTIPILYIKLYMYQLFRSLAYIHSQACV 56
>27546
Length = 426
Score = 35.8 bits (81), Expect = 0.030, Method: Compositional matrix adjust.
Identities = 24/101 (23%), Positives = 47/101 (46%), Gaps = 11/101 (10%)
Frame = -1
Query: 92 PNIITLADIVKDPVSRTPAL-----------VFEHVNNTDFKQLYQTLTDYDIRFYMYEI 140
PNII + I++ R P + + H+ T + + + + +++
Sbjct: 300 PNIIQIHSILQ----RGPKIFIFMRYAEKGDMLSHIKKTG------PIDEAQTKVWFFQM 151
Query: 141 LKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEF 181
KAL Y HS I HRD+K N+++ + +++ D+G A +
Sbjct: 150 AKALQYLHSHDIAHRDLKCENILLS-KRLNVKIADFGFARY 31
>02638
Length = 1490
Score = 35.4 bits (80), Expect = 0.045, Method: Compositional matrix adjust.
Identities = 31/128 (24%), Positives = 52/128 (40%)
Frame = +1
Query: 197 FKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYD 256
F PE+L + Y + D+WS+GC++ M + P ++ HD + L I K+ +
Sbjct: 34 FMAPEVL-RGESYGRACDVWSVGCVMIEMCTCRPP-WNSHDISNHLALIFKIASS----- 192
Query: 257 YIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAR 316
+D I EN +SP D + + L D R +A+
Sbjct: 193 -VDPPPI-----------------------PEN---MSPPVRDLMLRCLEQDSDFRPSAK 291
Query: 317 EAMEHPYF 324
+ + HP F
Sbjct: 292 DLLMHPLF 315
>28157
Length = 400
Score = 34.7 bits (78), Expect = 0.060, Method: Compositional matrix adjust.
Identities = 29/105 (27%), Positives = 46/105 (43%), Gaps = 13/105 (12%)
Frame = +3
Query: 92 PNIITLADIVKD-PVSRTPALVFEHVNNTDFKQLYQTL---------TDYDIRFYMYEIL 141
PNI+ L +D PV LV E+ LY L T ++ +
Sbjct: 90 PNIVCLYGACRDHPV----CLVMEYAEGGS---LYNVLHGSGPQPQYTAAHAMNWLLQCA 248
Query: 142 KALDYCHSM---GIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYH 183
++Y H M ++HRD+KP N+++ KL++ D+G A H
Sbjct: 249 LGVEYLHGMKPKALIHRDLKPPNLLLIQCGTKLKICDFGTACDIH 383
>18481
Length = 437
Score = 34.7 bits (78), Expect = 0.062, Method: Compositional matrix adjust.
Identities = 19/51 (37%), Positives = 31/51 (60%), Gaps = 3/51 (5%)
Frame = -1
Query: 139 EILKALDYCHSMGIMHRDVKPHNVMID---HEHRKLRLIDWGLAEFYHPGQ 186
++L L++ H +HRD+KP N ++ H HR L +ID+GL++ Y Q
Sbjct: 173 QLLSRLEFIHQKCFIHRDLKPDNFLMGLGRHCHR-LYIIDFGLSKRYKDTQ 24
>29360
Length = 363
Score = 33.9 bits (76), Expect = 0.10, Method: Composition-based stats.
Identities = 21/66 (31%), Positives = 33/66 (50%), Gaps = 14/66 (21%)
Frame = +3
Query: 113 FEHVNNT--DFKQLYQTLTDY------------DIRFYMYEILKALDYCHSMGIMHRDVK 158
F+H N+T F+ L Q L D+ IR ++L AL +G++H D+K
Sbjct: 162 FQHKNHTCLVFEMLEQNLYDFLKQNKFQPLPLKYIRPITQQVLTALRKLKQLGLIHADLK 341
Query: 159 PHNVMI 164
P N+M+
Sbjct: 342 PENIML 359
>15931
Length = 447
Score = 33.5 bits (75), Expect = 0.14, Method: Compositional matrix adjust.
Identities = 12/29 (41%), Positives = 20/29 (68%)
Frame = +1
Query: 296 EALDFLDKLLRYDHQSRLTAREAMEHPYF 324
+ D +DK+L Y+ +R + R+AM HP+F
Sbjct: 70 QLFDLMDKMLSYEVSTRYSLRQAMRHPFF 156
>19301
Length = 712
Score = 33.1 bits (74), Expect = 0.18, Method: Compositional matrix adjust.
Identities = 28/105 (26%), Positives = 53/105 (50%), Gaps = 10/105 (9%)
Frame = +2
Query: 85 LENLR--GGPNIITLADIVKDPVSRTPA--LVFEHVNNTDFKQLYQTLTDYD------IR 134
+ NLR PNII+ K ++ P ++ E+ + QLY+ L D +
Sbjct: 422 IRNLRKLNHPNIISF----KGVCTQAPCYCIIMEYC---PYGQLYEVLRDGKEIPPALVL 580
Query: 135 FYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLA 179
+ +I ++Y HS I+HRD+K NV++ ++ +++ D+G +
Sbjct: 581 DWSKQIASGMNYLHSHKIIHRDLKSPNVLV-AKNDVVKISDFGTS 712
>26909
Length = 394
Score = 33.1 bits (74), Expect = 0.20, Method: Compositional matrix adjust.
Identities = 29/109 (26%), Positives = 43/109 (39%), Gaps = 10/109 (9%)
Frame = +2
Query: 226 IFRKEPFFHGHD---------NYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRH 276
+ EP FH ++DQL RI V+G D+ D + + R
Sbjct: 14 LLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFPQEKDWEDIRRMPEHQQLTKDFKRS 193
Query: 277 SRKRWERFVHSENQHL-VSPEALDFLDKLLRYDHQSRLTAREAMEHPYF 324
S + E + +A L KLL D R+T+ +AM+ PYF
Sbjct: 194 SYVNCNLMKYMEKHKVKADSKAFHLLQKLLTMDPVKRITSEQAMKDPYF 340
>29590
Length = 320
Score = 32.7 bits (73), Expect = 0.24, Method: Composition-based stats.
Identities = 18/58 (31%), Positives = 28/58 (48%)
Frame = +3
Query: 175 DWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPF 232
D G A + G++ + + + PE+L DY+ DMWSLG + M+ PF
Sbjct: 6 DLGFACLTNTGEDIRDIIGTPDYVAPEVL-DYEPLSIQTDMWSLGVLSYVMLTACSPF 176
>11801
Length = 743
Score = 32.7 bits (73), Expect = 0.24, Method: Compositional matrix adjust.
Identities = 23/82 (28%), Positives = 42/82 (51%), Gaps = 3/82 (3%)
Frame = -1
Query: 226 IFRKEPFFHGHDNYDQLVR---IAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWE 282
+ +K P YDQL R +AKV+ + D++ I+LDP+++ + ++S +
Sbjct: 272 LLKKFPVTSSSIPYDQLQRRCSVAKVVSETSCCKFGDQF-IKLDPQYDYRVAKYSYLQSY 96
Query: 283 RFVHSENQHLVSPEALDFLDKL 304
R+ QH+ +AL F D +
Sbjct: 95 RYFDDHKQHIR--QALMFNDTI 36
>14104
Length = 573
Score = 32.7 bits (73), Expect = 0.27, Method: Compositional matrix adjust.
Identities = 11/32 (34%), Positives = 19/32 (59%)
Frame = +1
Query: 293 VSPEALDFLDKLLRYDHQSRLTAREAMEHPYF 324
+P+A+ F+ L+ D RLT + ++HPY
Sbjct: 88 AAPQAMSFMQSCLKMDPAERLTCHQLLQHPYM 183
>12672
Length = 773
Score = 30.8 bits (68), Expect = 0.90, Method: Compositional matrix adjust.
Identities = 23/92 (25%), Positives = 43/92 (46%), Gaps = 7/92 (7%)
Frame = +3
Query: 142 KALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPG-----QEYNVRVASRY 196
+ Y + G +HRD+K N+++D E+ ++ D+ G Q +V + +
Sbjct: 24 SGIQYLNDNGHVHRDIKTANILLDSEYTA-KVGDFATVVSAPSGEGKTVQNASVVIGTAA 200
Query: 197 FKGPELLVDYQMYDYS--LDMWSLGCMLASMI 226
+ PE + +D S LD +S G +L +I
Sbjct: 201 YLAPEAI----HFDVSTKLDSYSFGVVLLEVI 284
>27274
Length = 396
Score = 30.4 bits (67), Expect = 1.2, Method: Compositional matrix adjust.
Identities = 30/126 (23%), Positives = 50/126 (39%)
Frame = -1
Query: 199 GPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYI 258
G ELL Q + ++DMWSLG +L ++ PF Q+ R +
Sbjct: 381 GAELLRG-QQHGPTVDMWSLGILLHELLSGHVPF-EPERGSRQMARNMMAV--------- 235
Query: 259 DKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREA 318
+ I+ SR + +S DFL +L++ + RLT+++A
Sbjct: 234 ----------YAQIIRGSSRDVCDGLA-------LSTHGADFLRRLVQLEDTKRLTSQQA 106
Query: 319 MEHPYF 324
HP+
Sbjct: 105 FSHPWI 88
>35032
Length = 465
Score = 30.0 bits (66), Expect = 1.5, Method: Compositional matrix adjust.
Identities = 12/27 (44%), Positives = 16/27 (59%)
Frame = +3
Query: 299 DFLDKLLRYDHQSRLTAREAMEHPYFY 325
D + +LL YD RLT A+ HP+ Y
Sbjct: 147 DLVKRLLNYDPSKRLTPXXALAHPFLY 227
>37063
Length = 455
Score = 30.0 bits (66), Expect = 1.6, Method: Compositional matrix adjust.
Identities = 25/79 (31%), Positives = 37/79 (46%), Gaps = 13/79 (16%)
Frame = -2
Query: 157 VKPHNVMIDH--EHRKLRLIDWGLAEFYHPGQ------EYNVRVASRYFKGPELLVDYQM 208
+KP N++ +H E L++ D+ LA + E V S + PE+ VD +
Sbjct: 454 LKPENILCEHLDEVVPLKICDFDLASGINCDGDGTKTPELLTPVGSAEYMAPEV-VDAWV 278
Query: 209 -----YDYSLDMWSLGCML 222
YD DMWSLG +L
Sbjct: 277 GESFSYDKRCDMWSLGIIL 221
>17932
Length = 597
Score = 30.0 bits (66), Expect = 1.8, Method: Compositional matrix adjust.
Identities = 17/35 (48%), Positives = 22/35 (62%)
Frame = -3
Query: 293 VSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTV 327
VS EA D + +LL D +SRL E +HP+F TV
Sbjct: 460 VSKEARDLISQLLS-DGKSRLGWPELQQHPFFKTV 359
>16350
Length = 1108
Score = 29.6 bits (65), Expect = 2.0, Method: Compositional matrix adjust.
Identities = 10/26 (38%), Positives = 18/26 (69%)
Frame = +3
Query: 299 DFLDKLLRYDHQSRLTAREAMEHPYF 324
DFL +L +D + R TA ++++HP+
Sbjct: 762 DFLAPMLEFDPEQRATAAQSLQHPWL 839
>20773
Length = 391
Score = 29.3 bits (64), Expect = 2.9, Method: Composition-based stats.
Identities = 16/50 (32%), Positives = 25/50 (50%)
Frame = -1
Query: 274 GRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPY 323
G H R+ F H+ +V+ + + +LL YD RLT A+ HP+
Sbjct: 370 GLHRRRSRPVFPHTT---VVTQHFYNLVQRLLTYDPSQRLTPDLALSHPF 230
>20513
Length = 405
Score = 28.9 bits (63), Expect = 3.5, Method: Compositional matrix adjust.
Identities = 10/26 (38%), Positives = 18/26 (69%)
Frame = -1
Query: 299 DFLDKLLRYDHQSRLTAREAMEHPYF 324
DFL +L +D + R TA ++++HP+
Sbjct: 282 DFLAPMLEFDPEQRATAAQSLQHPWL 205
>18663
Length = 600
Score = 28.9 bits (63), Expect = 4.0, Method: Compositional matrix adjust.
Identities = 13/34 (38%), Positives = 21/34 (61%)
Frame = +2
Query: 199 GPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPF 232
PE+L + Y +S+D W+LG +L M+ + PF
Sbjct: 32 APEILRG-EDYGFSVDWWALGVLLYEMLAGRSPF 130
>28419
Length = 687
Score = 28.1 bits (61), Expect = 6.1, Method: Compositional matrix adjust.
Identities = 22/77 (28%), Positives = 37/77 (48%), Gaps = 5/77 (6%)
Frame = +3
Query: 140 ILKALDYCHSMG----IMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASR 195
ILK L YC ++ ++ K N+ EH K++ + G + +R S+
Sbjct: 342 ILKRLRYCLNLSKPPSYLNTVRKL*NISYVREHDKVKALMLGFKLLVNSQCANALRHPSQ 521
Query: 196 YFKGPELL-VDYQMYDY 211
KGPEL+ D+Q Y++
Sbjct: 522 I*KGPELIPYDFQFYEF 572
>20152
Length = 445
Score = 27.7 bits (60), Expect = 8.3, Method: Compositional matrix adjust.
Identities = 12/39 (30%), Positives = 23/39 (58%)
Frame = +1
Query: 200 PELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDN 238
PE+L+ ++D+WSLG +L ++ + PF +D+
Sbjct: 1 PEILLGDSYDAPAVDVWSLGVILYMLVVGEAPFQEANDS 117
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000362917 | hsapiens_gene_ensembl | Cell division
control protein 2 homolog (EC 2.7.11.22) (EC 2.7.11.23) (p34 protein
kinase) (Cyclin-dependent kinase 1) (CDK1).
[Source:Uniprot/SWISSPROT;Acc:P06493]
(297 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
01060 402 e-112
14126 252 1e-67
01966 239 3e-65
01756 211 4e-55
32000 205 2e-53
01707 205 2e-53
29581 188 2e-48
04591 173 8e-44
04138 150 6e-37
24241 142 1e-34
03294 131 3e-31
20559 102 3e-28
18921 103 6e-23
13592 100 1e-21
23319 96 2e-20
06405 95 4e-20
00300 94 8e-20
12721 92 2e-19
15910 91 5e-19
09606 90 1e-18
01718 89 3e-18
17975 87 1e-17
14420 83 1e-16
28638 63 5e-16
19761 80 8e-16
03508 80 1e-15
03240 79 3e-15
04852 76 2e-14
19301 76 2e-14
21808 76 2e-14
12453 76 2e-14
11780 75 3e-14
13066 75 4e-14
21433 58 4e-12
01392 68 4e-12
31885 67 6e-12
18484 67 7e-12
27405 67 9e-12
27546 67 1e-11
18287 66 2e-11
00392 65 3e-11
26560 65 4e-11
30755 64 6e-11
19094 64 9e-11
14477 62 4e-10
26909 61 4e-10
13212 60 7e-10
14116 60 8e-10
17253 60 1e-09
07940 59 2e-09
31489 59 2e-09
26711 56 2e-08
18401 56 2e-08
28157 55 2e-08
32359 46 4e-08
22005 55 5e-08
00715 54 6e-08
21079 54 7e-08
11185 51 7e-07
16708 50 8e-07
13840 49 3e-06
07291 49 3e-06
01106 48 5e-06
16003 48 6e-06
20640 47 1e-05
13078 47 1e-05
36481 46 1e-05
12786 46 2e-05
18996 46 2e-05
11404 45 2e-05
06358 44 7e-05
05084 44 9e-05
26156 42 1e-04
16350 43 1e-04
17300 42 2e-04
31789 42 4e-04
37602 40 8e-04
02638 40 0.001
20152 40 0.001
25019 40 0.001
07836 40 0.002
00638 39 0.002
26009 38 0.004
12672 38 0.004
00394 38 0.006
21800 37 0.007
15549 36 0.015
20773 34 0.056
17644 34 0.087
18481 33 0.17
32357 33 0.17
38560 33 0.21
35032 32 0.30
15931 32 0.41
20513 30 1.3
29360 29 1.9
01007 29 3.0
21210 28 3.1
17516 28 5.7
13305 28 5.7
17806 27 8.4
26052 27 8.8
>01060
Length = 1800
Score = 402 bits (1032), Expect = e-112, Method: Compositional matrix adjust.
Identities = 176/295 (59%), Positives = 228/295 (77%)
Frame = +1
Query: 1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH 60
+ D T +KIGEGTYGVVYK RH+ TG+ +AMKKIRL E+GVPS+AIREI++L+ELRH
Sbjct: 70 LSDLTDFQKIGEGTYGVVYKCRHRATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELRH 249
Query: 61 PNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCH 120
NIV L+DV+M+D RL+L+FEFLSMDLK Y+D P G +D LVKSY++QI+ GI FCH
Sbjct: 250 TNIVCLEDVIMEDERLFLVFEFLSMDLKMYIDKFPEGVVLDRRLVKSYVFQIVTGIXFCH 429
Query: 121 SRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEAITLWYRSPEVLLGSAR 180
RR++HRDLKPQNLLI+ G IK+ADFG+AR F +P+R YTHE +TLWYR+PE+L+G+++
Sbjct: 430 QRRIVHRDLKPQNLLINHTGAIKIADFGMARTFALPVRAYTHEVVTLWYRAPEILMGASK 609
Query: 181 YSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNT 240
YSTPVD+WSIGTIFA++ + P+F GDSEIDQLF+IFR +GTP + WPE L +
Sbjct: 610 YSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKLPAFNGM 789
Query: 241 FPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLDNQIK 295
FP WK G L+ + +LD GLDL+ + L DPA+RIS K L H YF ++D +K
Sbjct: 790 FPLWKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYFLNVDTSVK 954
>14126
Length = 1265
Score = 252 bits (644), Expect = 1e-67, Method: Compositional matrix adjust.
Identities = 143/302 (47%), Positives = 189/302 (62%), Gaps = 11/302 (3%)
Frame = +3
Query: 2 EDYTKIEKIGEGTYGVVYKGRH-KTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELR- 59
+ Y ++ IG G YG VYK R + G+ VAMK+IRL + EEG+P AIREIS+LK+L
Sbjct: 189 QKYEEVAVIGNGAYGTVYKARDLRNQGEFVAMKRIRLNNTEEGMPMMAIREISMLKQLEQ 368
Query: 60 --HPNIVSLQDVLM-----QDSRLYLIFEFLSMDLKKYLDSIP-PGQYMDSSLVKSYLYQ 111
HPN+V L DV ++ RL L+FE++ DL YL P PG D +K + Q
Sbjct: 369 YEHPNVVRLLDVSHNTITDREIRLNLVFEYIEHDLATYLAKCPSPGLGPDR--IKDLMLQ 542
Query: 112 ILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEAITLWYRS 171
+L G+ F HS R++HRDLKPQNLLI G +KLADFGLAR + + + T +TLWYRS
Sbjct: 543 LLNGVDFLHSNRIVHRDLKPQNLLISKDGRLKLADFGLARIYSFHMALTT-VVVTLWYRS 719
Query: 172 PEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEV 231
PEVL+ A Y T VDIWS G IFAEL T++ LF G SE DQL +IF +G P WPE
Sbjct: 720 PEVLM-QAEYGTSVDIWSCGCIFAELFTRRALFKGSSEFDQLKKIFEVIGLPPAGDWPEG 896
Query: 232 ESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYF-NDL 290
S+ ++N+F P L + V +D DL+ KML++ +RIS + +L HPY +DL
Sbjct: 897 VSV--HRNSFRPTPPVPLQTLVPEMDPQAKDLMEKMLVFKSGRRISSRESLLHPYLRDDL 1070
Query: 291 DN 292
D+
Sbjct: 1071DS 1076
>01966
Length = 1735
Score = 239 bits (609), Expect(2) = 3e-65, Method: Compositional matrix adjust.
Identities = 115/223 (51%), Positives = 152/223 (68%), Gaps = 3/223 (1%)
Frame = -1
Query: 22 RHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQDVLMQDSRLYLIFE 81
RH+ TG+ +AMKKIRL E+GVPS+AIREI++L+ELRH NIV L+DV+M+D RL+L+FE
Sbjct: 1651 RHRATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTNIVCLEDVIMEDERLFLVFE 1472
Query: 82 FLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGT 141
FLSMDLK Y+D P G +D LVKSY++QI+ GI FCH RR++HRDLKPQNLLI+ G
Sbjct: 1471 FLSMDLKMYIDKFPEGVVLDRRLVKSYVFQIVTGINFCHQRRIVHRDLKPQNLLINHTGA 1292
Query: 142 IKLADFGLARAFGIPIRVYTHEAITLWYRSPEVLLGSARYSTPVDIWSIGTI--FAELAT 199
IK+ADFG+AR F +P+R YTHE +TLWYR+PE+L+G STP W+ G + + + +
Sbjct: 1291 IKIADFGMARTFALPVRAYTHEVVTLWYRAPEILMGPQ--STP-PXWTCGALEPSSPICS 1121
Query: 200 KKPL-FHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNTF 241
PL ++ R +L N P S Q F
Sbjct: 1120 SGPLSSRATPKLTSFLRYSGSLALQRNRRGPSFTSCQHSMACF 992
Score = 27.3 bits (59), Expect(2) = 3e-65, Method: Compositional matrix adjust.
Identities = 11/14 (78%), Positives = 13/14 (92%)
Frame = -2
Query: 6 KIEKIGEGTYGVVY 19
++ KIGEGTYGVVY
Sbjct: 1698 RLSKIGEGTYGVVY 1657
Score = 142 bits (357), Expect = 2e-34, Method: Compositional matrix adjust.
Identities = 62/119 (52%), Positives = 83/119 (69%)
Frame = -3
Query: 177 GSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQD 236
G+++YSTPVD+WSIGTIFA++ + P+F GDSEIDQLF+IFR +GTP + WPE L
Sbjct: 1187 GASKYSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKLPA 1008
Query: 237 YKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLDNQIK 295
+ FP WK G L+ + +LD GLDL+ + L DPA+RIS K L H YF ++D +K
Sbjct: 1007 FNGMFPLWKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYFLNVDTSVK 831
>01756
Length = 1858
Score = 211 bits (536), Expect = 4e-55, Method: Compositional matrix adjust.
Identities = 122/298 (40%), Positives = 177/298 (59%), Gaps = 14/298 (4%)
Frame = -3
Query: 4 YTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNI 63
Y K+ KIG+GT+G V+K R K T QVVAMKK+ +++E+EG P TA+REI +L+ L H N+
Sbjct: 1736 YEKLAKIGQGTFGEVFKARCKKTKQVVAMKKVLMDNEKEGFPITALREIKILQLLNHENV 1557
Query: 64 VSLQDVLMQD--------SRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQG 115
V L ++ S YL+FEF DL L ++ + +K + Q++ G
Sbjct: 1556 VDLIEICSTKATSANRYKSMFYLVFEFCEHDLAGLLSNM--SVVFNLPEIKEVMKQLMNG 1383
Query: 116 IVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRV---YTHEAITLWYRSP 172
+ + H ++LHRD+K N+LI +G +KLADFGLARAF + +R YT+ +TLWYR P
Sbjct: 1382 LYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRPP 1203
Query: 173 EVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVE 232
E+LLG YST +D W G I AE+ T+ P+ G +E +QL I + G+ EVWP VE
Sbjct: 1202 ELLLGDRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQNQLTLITQLCGSITPEVWPGVE 1023
Query: 233 SLQDYKN-TFPKWKPGSLASHVKNL--DENGLDLLSKMLIYDPAKRISGKMALNHPYF 287
L+ Y + P+ + ++ D LDLL K+L DP KR++ AL+H +F
Sbjct: 1022 RLELYNSLDLPQGNKRKVKERLRYYIKDAYALDLLDKLLALDPGKRVNSDEALSHDFF 849
>32000
Length = 644
Score = 205 bits (522), Expect = 2e-53, Method: Compositional matrix adjust.
Identities = 93/149 (62%), Positives = 116/149 (77%)
Frame = -1
Query: 142 IKLADFGLARAFGIPIRVYTHEAITLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKK 201
+K+ADFGLAR FG+P+R YTHE ITLWYR+PE+LLG YS PVDIWS+G IF E+ T++
Sbjct: 572 MKIADFGLARVFGLPVRTYTHEVITLWYRAPEILLGCRFYSVPVDIWSLGCIFVEMMTRR 393
Query: 202 PLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNTFPKWKPGSLASHVKNLDENGL 261
LF GDSEIDQL+RIFR LGTP+ +VWP V L DYK TFPKW +L + V +L + GL
Sbjct: 392 ALFPGDSEIDQLYRIFRTLGTPDEKVWPGVSKLPDYKPTFPKWPLKNLET-VVSLSKVGL 216
Query: 262 DLLSKMLIYDPAKRISGKMALNHPYFNDL 290
DLL +ML Y+P +RIS + A+ HPYFND+
Sbjct: 215 DLLKRMLTYNPNRRISARSAMRHPYFNDM 129
>01707
Length = 757
Score = 205 bits (521), Expect = 2e-53, Method: Compositional matrix adjust.
Identities = 104/222 (46%), Positives = 147/222 (66%), Gaps = 1/222 (0%)
Frame = +1
Query: 1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEG-VPSTAIREISLLKELR 59
ME Y KI KIGEG+YGVV+K R+K T Q+VA+KK +ESE++ + A+REI +LK+L+
Sbjct: 61 MEKYEKIGKIGEGSYGVVFKCRNKETSQLVAIKKF-VESEDDPLIKKIAMREIRMLKQLK 237
Query: 60 HPNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFC 119
HPN+V L +V + RL+L+F+++ L LD P G + +VK +YQ L + FC
Sbjct: 238 HPNLVRLIEVFRRKKRLHLVFDYVDHTLLNELDRYPRG--LPEPMVKRIIYQTLLAVNFC 411
Query: 120 HSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEAITLWYRSPEVLLGSA 179
H +HRD+KP+N+LI +G +KL DFG AR P YT T WYR+PE+L+G
Sbjct: 412 HQYNTIHRDVKPENILITRQGQVKLCDFGFARILTGPGDEYTDYVATRWYRAPELLVGDT 591
Query: 180 RYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALG 221
+Y PVD+W+IG +FAEL T + L+ G S++DQL I + LG
Sbjct: 592 QYGPPVDVWAIGCVFAELLTGQALWPGRSDVDQLHLIRKTLG 717
>29581
Length = 1278
Score = 188 bits (478), Expect = 2e-48, Method: Compositional matrix adjust.
Identities = 100/248 (40%), Positives = 145/248 (58%), Gaps = 3/248 (1%)
Frame = -2
Query: 45 PSTAIREISLLKELRHPNIVSLQDVLMQDS--RLYLIFEFLSMDLKKYLDSIPPGQYMDS 102
PS + L LRH NIV LQ+V++ S L+L+ E+ DL LD++P
Sbjct: 1223 PSVVCVRSTFLLNLRHQNIVQLQEVVVGKSLDSLFLVMEYCEQDLASLLDNMPAP--FSE 1050
Query: 103 SLVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTH 162
S VK + Q+L+G+ + H ++HRDLK NLL+ DKG +K+ADFGLAR +G P + T
Sbjct: 1049 SQVKCIVLQLLKGLRYLHEAFIIHRDLKVSNLLMTDKGCVKIADFGLARNYGKPQKPMTP 870
Query: 163 EAITLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGT 222
+ +TLWYR+PE+L GS +ST +D+WS G I EL KPL G S++ Q+ I LGT
Sbjct: 869 KVVTLWYRAPELLFGSKTHSTAIDMWSAGCILGELLGHKPLMPGRSDLQQIELIMELLGT 690
Query: 223 PNNEVWPEVESLQDYKNTFPKWKP-GSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMA 281
PN+ +WP L ++ K +P +L L E+G+ LL+ + +Y P KR + +
Sbjct: 689 PNDTIWPGFSQLPAFEQFTLKKQPYNNLRHTFPWLSESGIRLLNGLFMYHPQKRATAEDC 510
Query: 282 LNHPYFND 289
L H YF +
Sbjct: 509 LEHSYFKE 486
Score = 31.6 bits (70), Expect = 0.36, Method: Compositional matrix adjust.
Identities = 12/34 (35%), Positives = 23/34 (67%)
Frame = -1
Query: 28 QVVAMKKIRLESEEEGVPSTAIREISLLKELRHP 61
++VA+KK+R+ E G+P + +REI++ + P
Sbjct: 1275 EIVALKKMRMTGERYGIPISGLREINIFAQSATP 1174
>04591
Length = 1117
Score = 173 bits (438), Expect = 8e-44, Method: Compositional matrix adjust.
Identities = 99/260 (38%), Positives = 152/260 (58%), Gaps = 13/260 (5%)
Frame = -2
Query: 41 EEGVPSTAIREISLLKELRHPNIVSLQDVLMQD--------SRLYLIFEFLSMDLKKYLD 92
+EG P TA+REI +L++L H N+V LQ++ S YLIFE+ DL L+
Sbjct: 1101 KEGFPITALREIKILQQLEHENVVQLQEICHTQAGPYNRYKSTFYLIFEYCDYDLAGLLN 922
Query: 93 SIPPGQYMDSSLV--KSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLA 150
++ + SL K+ + Q+L G+ + H++++LHRD+K N+L+ G +KLADFGL+
Sbjct: 921 NL----RVKFSLADKKNLMSQLLNGLFYIHTKQILHRDIKAANILLTRDGVLKLADFGLS 754
Query: 151 RAFGIPIRVYTHEAITLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEI 210
R + + + T+ +TLWYR PE+LLG Y +D+W +G I AE+ ++KPL G SE
Sbjct: 753 RPW-VKSKRLTNRVVTLWYRPPELLLGEREYGPEIDMWGVGCIMAEMWSRKPLMQGRSEQ 577
Query: 211 DQLFRIFRALGTPNNEVWPEVESLQDY-KNTFPKWKPGSLASHVKNLDEN--GLDLLSKM 267
QL I G+ N EVWP V L+ Y K P+ KP + + +L +N G +L+
Sbjct: 576 HQLSLITDLCGSLNAEVWPGVTKLELYGKLDLPQGKPRKVKERMLDLLKNKEGAELIDIF 397
Query: 268 LIYDPAKRISGKMALNHPYF 287
L DP +R++ AL+H +F
Sbjct: 396 LRLDPGQRMNCDNALSHDFF 337
>04138
Length = 800
Score = 150 bits (379), Expect = 6e-37, Method: Compositional matrix adjust.
Identities = 79/185 (42%), Positives = 108/185 (58%), Gaps = 13/185 (7%)
Frame = +1
Query: 116 IVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRV---YTHEAITLWYRSP 172
+ + H ++LHRD+K N+LI +G +KLADFGLARAF + +R YT+ +TLWYR P
Sbjct: 52 LYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRPP 231
Query: 173 EVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVE 232
E+LLG YST +D W G I AE+ T+ P+ G +E +QL I + G+ EVWP V
Sbjct: 232 ELLLGDRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQNQLTLITQLCGSITPEVWPGVT 411
Query: 233 SLQDYKNTFPKWKPGSLASHVKNL----------DENGLDLLSKMLIYDPAKRISGKMAL 282
L Y G+LA+ KN+ D GLDL ++L DP++RIS AL
Sbjct: 412 QLSMYHQI-----KGALAAGRKNIIRDRFARILKDPYGLDLFERLLKMDPSQRISADEAL 576
Query: 283 NHPYF 287
NH +F
Sbjct: 577 NHDFF 591
>24241
Length = 413
Score = 142 bits (359), Expect = 1e-34, Method: Compositional matrix adjust.
Identities = 69/115 (60%), Positives = 88/115 (76%), Gaps = 1/115 (0%)
Frame = -2
Query: 6 KIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPN-IV 64
++ KIGEGTYGVVYK RH+ TG+ +AMKKIRL E+GVPS+AIREI++L+ELRH +V
Sbjct: 331 RLSKIGEGTYGVVYKCRHRATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTQXLV 152
Query: 65 SLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFC 119
L+DV+M+D RL+L+FEFLSMDLK Y+D P G +D LVK I+ GI FC
Sbjct: 151 CLEDVIMEDERLFLVFEFLSMDLKMYIDKFPEGVVLDRRLVK-----IVTGINFC 2
>03294
Length = 1684
Score = 131 bits (330), Expect = 3e-31, Method: Compositional matrix adjust.
Identities = 58/112 (51%), Positives = 76/112 (67%)
Frame = -1
Query: 184 PVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNTFPK 243
PVD+WSIGTIFA++ + P+F GDSEIDQLF+IFR +GTP + WPE L + FP
Sbjct: 1675 PVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKLPAFNGMFPL 1496
Query: 244 WKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLDNQIK 295
WK G L+ + +LD GLDL+ + L DPA+RIS K L H YF ++D +K
Sbjct: 1495 WKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYFLNVDTSVK 1340
>20559
Length = 430
Score = 102 bits (254), Expect(3) = 3e-28, Method: Compositional matrix adjust.
Identities = 45/80 (56%), Positives = 65/80 (81%)
Frame = -2
Query: 1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH 60
M+ Y K+EKIGEGTYG V+K +++ T ++VA+K++RL+ ++EGVPS+A+REI LLKEL+H
Sbjct: 378 MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKH 199
Query: 61 PNIVSLQDVLMQDSRLYLIF 80
NIV L DVL + +L L+F
Sbjct: 198 RNIVRLHDVLHSERKLTLVF 139
Score = 34.7 bits (78), Expect(3) = 3e-28, Method: Compositional matrix adjust.
Identities = 18/39 (46%), Positives = 27/39 (69%)
Frame = -3
Query: 80 FEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVF 118
FE+ DLKKY D+ G+ +D VKS+L+Q+L+G+ F
Sbjct: 140 FEYCDQDLKKYFDTC-NGE-IDPDTVKSFLHQLLRGLGF 30
Score = 25.0 bits (53), Expect(3) = 3e-28, Method: Compositional matrix adjust.
Identities = 9/14 (64%), Positives = 11/14 (78%)
Frame = -1
Query: 114 QGIVFCHSRRVLHR 127
+ +VFCHS VLHR
Sbjct: 43 EDLVFCHSNNVLHR 2
>18921
Length = 697
Score = 103 bits (258), Expect = 6e-23, Method: Compositional matrix adjust.
Identities = 60/194 (30%), Positives = 109/194 (56%)
Frame = +2
Query: 9 KIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQD 68
K+GEG+YG V+K HK TGQV+A+K++ ++++ + + I+EIS++++ IV
Sbjct: 50 KLGEGSYGSVFKSLHKETGQVLAIKQVPVDTDLQEI----IKEISIMQQCDSKYIVKYYG 217
Query: 69 VLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCHSRRVLHRD 128
+++ L+++ E+ + + ++ + + LY L+G+ + HSRR +HRD
Sbjct: 218 SYFKNTDLWIVMEYCGAGSVSDIMRLRNKTLVERE-IATILYYTLKGLXYLHSRRKIHRD 394
Query: 129 LKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEAITLWYRSPEVLLGSARYSTPVDIW 188
+K N+L++++G KLADFG+A + T ++ +PEV+ Y DIW
Sbjct: 395 IKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTPYWMAPEVIQ-EIGYDCVADIW 571
Query: 189 SIGTIFAELATKKP 202
S+G E+A KP
Sbjct: 572 SLGITALEMAEGKP 613
>13592
Length = 980
Score = 99.8 bits (247), Expect = 1e-21, Method: Compositional matrix adjust.
Identities = 72/282 (25%), Positives = 126/282 (44%), Gaps = 13/282 (4%)
Frame = +2
Query: 9 KIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQD 68
KIG+G +G VY + TG+++AMK+I ++ E E+ +L+ ++H N+V
Sbjct: 5 KIGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETRALKNVAEELKILEGIKHKNLVRYYG 184
Query: 69 VLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCHSRRVLHRD 128
+ + L + E S + L + G + +L + + Q+L G+ H ++HRD
Sbjct: 185 IEVHREELLIFMELCSEGTLESLVELTGG--LPEALSRRFTAQLLSGVAELHKHGIVHRD 358
Query: 129 LKPQNL-LIDDKGTIKLADFGLARAFGIPIRVYTHEAI---------TLWYRSPEVL--L 176
+K N+ L+D ++KL DFG A +++ H + T Y +PEV
Sbjct: 359 IKTANIFLVDGSNSLKLGDFGSA------VKIQAHTTVPGELQGYVGTQAYMAPEVFTKT 520
Query: 177 GSARYSTPVDIWSIGTIFAELAT-KKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQ 235
S + DIWS+G + E+A+ K+P ++ D F+I +G PE
Sbjct: 521 NSDGHGRLADIWSVGCVVVEMASGKRPW----AQFDSNFQIMFKVGMGEKPQAPE----- 673
Query: 236 DYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRIS 277
+L + G D + L +DP +R+S
Sbjct: 674 -------------------SLSQEGHDFIDHCLQHDPKQRLS 742
>23319
Length = 2235
Score = 95.9 bits (237), Expect = 2e-20, Method: Compositional matrix adjust.
Identities = 51/118 (43%), Positives = 71/118 (60%), Gaps = 2/118 (1%)
Frame = +3
Query: 181 YSTPVDIWSIGTIFAELATK-KPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKN 239
YST +D+WS G IFAELA +PLF G+ + DQL RIF+ LGTP + WP + L +Y+
Sbjct: 27 YSTSIDMWSAGCIFAELANAGRPLFPGNDDDDQLKRIFKLLGTPTEDQWPGMTQLPNYR- 203
Query: 240 TFPKWKPGSLASH-VKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLDNQIKK 296
FP + + V L+ G DLL +L+ P+ R+S AL HPYF DL +++
Sbjct: 204 MFPMYHVTTTWQQVVPKLNSKGRDLLQCLLVCCPSDRMSADEALQHPYFADLPPLVRQ 377
>06405
Length = 1965
Score = 94.7 bits (234), Expect = 4e-20, Method: Compositional matrix adjust.
Identities = 67/227 (29%), Positives = 119/227 (52%), Gaps = 10/227 (4%)
Frame = +1
Query: 9 KIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQD 68
++G G YG VY+ K ++VA+K ++ E+ + + E +++KE++HPN+V L
Sbjct: 280 RLGGGQYGDVYEAMWKRYNKIVAVKTLK---EDTMALNDFLEEAAIMKEMKHPNLVQLLG 450
Query: 69 VLMQDSRLYLIFEFLSM-DLKKYLDSIPPGQYMDSSLVKSYLY-QILQGIVFCHSRRVLH 126
V ++ Y++ EF+ +L YL S + ++L+ Y+ QI G+ + ++ +H
Sbjct: 451 VCTREPPFYIVTEFMPHGNLLDYLRSSTREENGPTALM--YMATQIASGMAYLETKNFIH 624
Query: 127 RDLKPQNLLIDDKGTIKLADFGLARAFGIPI-RVYTHEAITLWYRSPEVLLGSARYSTPV 185
RDL +N L+ D +K+ADFGLAR + + + +PE L + R+ST
Sbjct: 625 RDLAARNCLVADSNMVKVADFGLARLMKDDTYTAHIGAKFPIKWTAPEGLAFN-RFSTRS 801
Query: 186 DIWSIGTIFAELATKKPLFHGDSEIDQL-------FRIFRALGTPNN 225
DIW+ G + ELAT + E+ ++ +R+ R GTP +
Sbjct: 802 DIWAFGVLLWELATYGMSPYPGVELTEVYHLLERGYRMERPPGTPAD 942
>00300
Length = 2318
Score = 93.6 bits (231), Expect = 8e-20, Method: Compositional matrix adjust.
Identities = 65/289 (22%), Positives = 128/289 (44%), Gaps = 11/289 (3%)
Frame = -1
Query: 9 KIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQD 68
KIGEG +G VY + +TG+++A+K+++ + + EI + + ++H N+V
Sbjct: 1637 KIGEGQFGKVYTAVNMSTGELMALKEMKFQPNDLQQLREMCDEIKIFEGIQHENLVKYYG 1458
Query: 69 VLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCHSRRVLHRD 128
V + + + E+ + + +Y L++ Y +I+ + H ++HRD
Sbjct: 1457 VEVHKDEMLMFMEYCDTGTIEEAAKMGLPEY----LIRRYTREIVLAVNHLHENSIVHRD 1290
Query: 129 LKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEAI---------TLWYRSPEVLLGSA 179
+K N+ + G +KL DFG + +++ +H + T Y +PEV +
Sbjct: 1289 IKGANIFLTSNGHVKLGDFGCS------VKLKSHTTMPGEFHNLVGTTAYMAPEVFTQND 1128
Query: 180 R--YSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDY 237
+ Y DIWS+G + E+AT K +H ++D ++I +G + P+ S++
Sbjct: 1127 QGGYGRAADIWSLGCVVIEMATGKRPWH---DLDNNYQIMYKVGIGHKPAVPDSLSVE-- 963
Query: 238 KNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPY 286
G L ++ +DPA+R L+H +
Sbjct: 962 ----------------------GKHFLDLIMCHDPAQRALASQLLDHTF 882
>12721
Length = 821
Score = 92.4 bits (228), Expect = 2e-19, Method: Compositional matrix adjust.
Identities = 56/208 (26%), Positives = 102/208 (49%)
Frame = +1
Query: 9 KIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQD 68
KIGEG+ G+V + G+ +A+KK+ L ++ E+ ++++ HPNIV + +
Sbjct: 109 KIGEGSTGIVCIATSRD-GRQMAVKKMDLRKQQRR--ELLFNEVVVMRDYHHPNIVEMYN 279
Query: 69 VLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCHSRRVLHRD 128
+ + L+++ EF+ L I MD + + L+ + F H+ V+HRD
Sbjct: 280 SYLVNDELWVVMEFME---GGALTDIVTNNRMDEVQIATVCRACLKALAFLHANGVIHRD 450
Query: 129 LKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEAITLWYRSPEVLLGSARYSTPVDIW 188
+K ++L+ G +KL DFG ++ T ++ +PEV + Y VDIW
Sbjct: 451 IKSDSILLSHDGKVKLXDFGFCAQVTQDLQKRKSLVGTPYWMAPEV-ISRLPYGPEVDIW 627
Query: 189 SIGTIFAELATKKPLFHGDSEIDQLFRI 216
S+G + E+ +P F + + + RI
Sbjct: 628 SLGIMVMEMIDAEPPFFNEPPLQAMRRI 711
>15910
Length = 1361
Score = 90.9 bits (224), Expect = 5e-19, Method: Compositional matrix adjust.
Identities = 61/204 (29%), Positives = 97/204 (47%), Gaps = 3/204 (1%)
Frame = +2
Query: 97 GQYMDSSLVKSYLYQILQGIVFCHSRRVLHRDLKPQNLL---IDDKGTIKLADFGLARAF 153
GQY + ++ + IL G+ + H+ V+HRDLKP+NLL + D +KLADFGL+R
Sbjct: 449 GQYTEKDAARA-ISDILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLADFGLSRII 625
Query: 154 GIPIRVYTHEAITLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQL 213
+++ T T Y +PEVL G +Y+ VD+WS+G I L F ++E +
Sbjct: 626 EPEVQMSTVCG-TPGYCAPEVLKGD-KYTPSVDMWSVGVIAYILLCGYEPFFAENEFEMY 799
Query: 214 FRIFRALGTPNNEVWPEVESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPA 273
+I + + E W E+ EN D++ K+L+ DP
Sbjct: 800 RKIIKGEYKFDEEYWSEI-------------------------SENAKDVVRKLLVIDPK 904
Query: 274 KRISGKMALNHPYFNDLDNQIKKM 297
KR++ AL P+ + + M
Sbjct: 905 KRLTATEALRLPWVKGVATKTTNM 976
>09606
Length = 1300
Score = 90.1 bits (222), Expect = 1e-18, Method: Compositional matrix adjust.
Identities = 58/230 (25%), Positives = 105/230 (45%), Gaps = 22/230 (9%)
Frame = -3
Query: 1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH 60
ME++ E++G+G + ++YKGR K T VA+ I E + + ++ H
Sbjct: 1118 MENFVLYEELGKGEHSIIYKGRRKGTINFVAIHCIEKCKRPE-----VTNTVRMTHDISH 954
Query: 61 PNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCH 120
PN+V + + L+L+ E + D + ++ + ++ + ++ G+ + H
Sbjct: 953 PNVVQFHEWYETSNHLWLVVELCTGG--SLADILAQDHHLPETSIRDFGIHLVTGLHYIH 780
Query: 121 SRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIR---VYTHEAITLW--------- 168
S +L DL+P +L+D G +K ADFGL++ G + EA W
Sbjct: 779 SLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQWNIQSAEEMM 600
Query: 169 ----------YRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDS 208
Y +PEV G A S D+W++G +F E+ + P F G++
Sbjct: 599 KQVPTSGSPTYMAPEVFQG-AEPSIMSDLWALGCVFYEMFSGHPPFLGET 453
>01718
Length = 959
Score = 88.6 bits (218), Expect = 3e-18, Method: Compositional matrix adjust.
Identities = 64/206 (31%), Positives = 107/206 (51%), Gaps = 10/206 (4%)
Frame = +3
Query: 7 IEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSL 66
EKIG G + V+K H+ TGQV+A+K + S + +RE+ LL L+H NI+
Sbjct: 162 CEKIGAGFFSEVFKVTHRITGQVMALKMNTMTSNRHNM----LREVQLLNRLQHANILRF 329
Query: 67 QDVLMQDSRLYLIFEF-----LSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCHS 121
V + + +L+ + E+ L L+K + +P Q + +L + +G+ + HS
Sbjct: 330 MGVCVHEGQLHALTEYIPSGNLEQLLEKKDEELPWTQRIQLTL------GLARGLDYLHS 491
Query: 122 RRVLHRDLKPQNLLI---DDKG-TIKLADFGLARAFGIPIRVYTHEAI-TLWYRSPEVLL 176
R +HRDL +N+LI D+ G +ADFGLA P+ + + ++ +PEVL
Sbjct: 492 TRFIHRDLTSKNILIRREDNHGYHAVIADFGLATKIPDPLDKEKLPTVGSPYWMAPEVLN 671
Query: 177 GSARYSTPVDIWSIGTIFAELATKKP 202
G Y+ D++S+G I E+ + P
Sbjct: 672 GHF-YNERADLFSVGIIMCEITARIP 746
>17975
Length = 449
Score = 86.7 bits (213), Expect = 1e-17, Method: Compositional matrix adjust.
Identities = 51/138 (36%), Positives = 79/138 (57%), Gaps = 2/138 (1%)
Frame = +3
Query: 15 YGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQDVLMQDS 74
+ VV RH TG+ VA+K I +E S +E+ +K ++HPN+V L +V+ +
Sbjct: 6 FAVVKLARHVFTGEKVAVKVIDKTKLDEVSRSHLFQEVRCMKLVQHPNVVRLYEVIDTQT 185
Query: 75 RLYLIFEFL-SMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCHSRRVLHRDLKPQN 133
+LYLI E D+ Y+ G ++ L K Y QI++ I +CH V+HRDLKP+N
Sbjct: 186 KLYLILELGDGGDMYDYIMRHSGG--LEEKLAKRYFRQIVEAISYCHKLHVVHRDLKPEN 359
Query: 134 LLIDDK-GTIKLADFGLA 150
++ +K G +KL DFG +
Sbjct: 360 VVFFEKPGLVKLTDFGFS 413
>14420
Length = 528
Score = 83.2 bits (204), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 47/165 (28%), Positives = 84/165 (50%)
Frame = +2
Query: 49 IREISLLKELRHPNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSY 108
I EI +++E ++PNIV+ D + L+++ EFL+ L + MD + +
Sbjct: 44 INEILVMRENQNPNIVNYLDSYLVGEELWVVMEFLA---GGSLTDVVTETCMDEGQIAAV 214
Query: 109 LYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEAITLW 168
+ LQ + F H +V+HRD+K N+L+ G++KL DFG + T +
Sbjct: 215 CRECLQALEFLHENQVIHRDIKSDNILLGMDGSVKLTDFGFCAQLSPEQSKRSTMVGTPY 394
Query: 169 YRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQL 213
+ +PEV+ +Y VDIWS+G + E+ +P + ++ + L
Sbjct: 395 WMAPEVVT-RKQYGPTVDIWSLGVMCIEMIEGEPPYLNENPLRAL 526
>28638
Length = 1458
Score = 63.2 bits (152), Expect(2) = 5e-16, Method: Compositional matrix adjust.
Identities = 36/104 (34%), Positives = 58/104 (55%), Gaps = 4/104 (3%)
Frame = -1
Query: 103 SLVKSYLYQILQGIVFCHS--RRVLHRDLKPQNLLIDD--KGTIKLADFGLARAFGIPIR 158
+L + + Q+ ++F + ++H DLKP+N+L+ + + IK+ DFG + G I
Sbjct: 837 NLTRKFAQQLCTALLFLATPEMNIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIY 658
Query: 159 VYTHEAITLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKP 202
Y +YRSPEVLLG Y +D+WS+G I E+ T +P
Sbjct: 657 QYIQSR---FYRSPEVLLG-VPYDLAIDMWSLGCILVEMHTGEP 538
Score = 38.1 bits (87), Expect(2) = 5e-16, Method: Compositional matrix adjust.
Identities = 33/126 (26%), Positives = 50/126 (39%), Gaps = 34/126 (26%)
Frame = -2
Query: 202 PLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNTFP-------------KWK-PG 247
PLF G +E DQ+ +I LG P + + + + Y + P K+K P
Sbjct: 539 PLFAGSNEFDQMMKIVEVLGVPPRHILDQAQKTRKYFDLLPDGTYAPKKPRDNKKYKSPS 360
Query: 248 SLASHV-----------KNLDENG---------LDLLSKMLIYDPAKRISGKMALNHPYF 287
S H + + E G DL+ +ML +DP RIS AL H +F
Sbjct: 359 SRKLHEVLGAEKGGPGGRRMGEPGHTVADYLKFKDLILRMLDFDPKTRISPYYALQHNFF 180
Query: 288 NDLDNQ 293
++
Sbjct: 179 RKTSDE 162
>19761
Length = 473
Score = 80.5 bits (197), Expect = 8e-16, Method: Compositional matrix adjust.
Identities = 42/120 (35%), Positives = 67/120 (55%), Gaps = 2/120 (1%)
Frame = -3
Query: 104 LVKSYLYQILQGIVFCHSRR--VLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYT 161
L+ +L Q + + H+ +LHRDLKPQN+ + +KG ++L D GLAR P T
Sbjct: 420 LIVCWLMQTASALNYMHTHTPVILHRDLKPQNIYVTEKGDVRLGDLGLARKLTGPADFAT 241
Query: 162 HEAITLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALG 221
+ T+ Y SPE+ L Y++ DIWS+G +F ++ KK G E+ +F + + +G
Sbjct: 240 SQVGTIMYLSPEI-LSQQPYNSKSDIWSLGCVFYDITGKK----GSDEMGVMFLLVQVMG 76
>03508
Length = 1463
Score = 79.7 bits (195), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 60/205 (29%), Positives = 108/205 (52%), Gaps = 5/205 (2%)
Frame = +1
Query: 2 EDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH- 60
+DY + K+G G Y V++ + T + K ++ + REI +L+ LR
Sbjct: 589 DDYQIVRKLGRGKYSEVFEAINVTNNE-----KCVIKILKPVKKKKIKREIKILENLRGG 753
Query: 61 PNIVSLQDVLMQD-SRL-YLIFEFLS-MDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIV 117
N+++L ++ SR LIFE ++ D K+ + ++ YLY++++ +
Sbjct: 754 TNVITLLAIVKDPVSRTPALIFEHVNNTDFKQLYQTFTDYD------IRFYLYELMKALD 915
Query: 118 FCHSRRVLHRDLKPQNLLID-DKGTIKLADFGLARAFGIPIRVYTHEAITLWYRSPEVLL 176
FCHS ++HRD+KP N++ID + ++L D+GLA F P Y + +++ PE+LL
Sbjct: 916 FCHSMGIMHRDVKPHNVMIDHENKKLRLIDWGLAE-FYHPGMEYNVRVASRYFKGPELLL 1092
Query: 177 GSARYSTPVDIWSIGTIFAELATKK 201
Y +D+WS+G +FA + +K
Sbjct: 1093DYQMYDYSLDMWSLGCMFASMIFRK 1167
Score = 52.8 bits (125), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 35/114 (30%), Positives = 55/114 (48%), Gaps = 14/114 (12%)
Frame = +2
Query: 188 WSIGTIFAEL----ATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQ-DYKNTF- 241
W+ G A L + K P FHG DQL RI + LGT ++++ +E Q D F
Sbjct: 1118 WTCGVWAACLPA*SSGKSPFFHGHDNYDQLVRIAKVLGT--DDLYGYIEKYQIDLDPRFN 1291
Query: 242 --------PKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYF 287
+W+ + + + LD L K+L YD +R++ + A++HPYF
Sbjct: 1292 DILGRHSRKRWERFVHSENQHLISPEALDFLDKLLRYDHNERLTAREAMDHPYF 1453
>03240
Length = 1683
Score = 78.6 bits (192), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 66/271 (24%), Positives = 108/271 (39%), Gaps = 57/271 (21%)
Frame = -3
Query: 4 YTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNI 63
+ KI+ +G G +G V R TG + AMK +R+ +LK + ++
Sbjct: 1285 FEKIKTLGVGAFGEVSLCRKNDTGMLYAMK--------------TLRKSDVLKRNQVAHV 1148
Query: 64 VSLQDVLMQDSRLYLIFEFLSMDLKKYL----DSIPPGQYM---------DSSLVKSYLY 110
+ +D+L + +++ + S YL D +P G M D L + Y+
Sbjct: 1147 KAERDILAEADNEWVVKLYYSFQDHNYLYFVMDYVPGGDLMGLLIRMEILDEPLARFYVA 968
Query: 111 QILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFG---------------- 154
+++Q I H +HRD+KP N+LID G IKL DFGL F
Sbjct: 967 ELVQAIESVHRMGFIHRDIKPDNILIDRNGHIKLTDFGLCTGFRWTHNSKYYQRDGTHAR 788
Query: 155 -------------------IPI--------RVYTHEAI-TLWYRSPEVLLGSARYSTPVD 186
P+ R H + T Y +PEVL Y++ D
Sbjct: 787 QDSMEVKCQLDEQCQCEILKPLERRRKREQRCLAHSLVGTPNYIAPEVLSRLGGYTSVCD 608
Query: 187 IWSIGTIFAELATKKPLFHGDSEIDQLFRIF 217
WS+G I E+ P F+ ++ + +++
Sbjct: 607 WWSVGVILFEMLVGHPPFYANTPAETQYKVI 515
>04852
Length = 1462
Score = 76.3 bits (186), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 52/184 (28%), Positives = 89/184 (48%), Gaps = 33/184 (17%)
Frame = +1
Query: 47 TAIREISLLKELR----------HPNIVSLQDVLMQDSRLYLIFEFL-SMDLKKYLDSI- 94
TA+ E ++EL+ H NIV+ Q L++I EF + +L+ +L+S
Sbjct: 58 TAVEEQDFVQELQVMKAVKKMGSHINIVNFLGCCTQGGPLWVIVEFAKNGNLRDFLESCR 237
Query: 95 ---------------------PPGQYMDSSLVKSYLYQILQGIVFCHSRRVLHRDLKPQN 133
P G + + SY +QI +G+ F SR+ +HRDL +N
Sbjct: 238 DGINGYGKFVSPQDPGWYTKTPGGHVIRRKNLLSYAFQIARGMEFLASRKCIHRDLAARN 417
Query: 134 LLIDDKGTIKLADFGLARAFGIPIRVYTHEAITLWYRSPEVLLGSARYSTPVDIWSIGTI 193
+L+ ++ +K+ADFGL+R G + + + + + +PE L RY+T D+WS G +
Sbjct: 418 VLVTEEHVLKIADFGLSRT-GDYYKKRSGGRLPVKWMAPEALF-DMRYTTKSDVWSFGVV 591
Query: 194 FAEL 197
E+
Sbjct: 592 LWEI 603
>19301
Length = 712
Score = 75.9 bits (185), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 47/150 (31%), Positives = 78/150 (52%)
Frame = +2
Query: 1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH 60
E T +E +G G G V+ G K + VA+KK+R + T IR L++L H
Sbjct: 302 FESITDLEWLGSGAQGAVFLG--KLCAEEVAVKKVR------DIKETDIRN---LRKLNH 448
Query: 61 PNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCH 120
PNI+S + V Q +I E+ + + + G+ + +LV + QI G+ + H
Sbjct: 449 PNIISFKGVCTQAPCYCIIMEYCP--YGQLYEVLRDGKEIPPALVLDWSKQIASGMNYLH 622
Query: 121 SRRVLHRDLKPQNLLIDDKGTIKLADFGLA 150
S +++HRDLK N+L+ +K++DFG +
Sbjct: 623 SHKIIHRDLKSPNVLVAKNDVVKISDFGTS 712
>21808
Length = 1011
Score = 75.9 bits (185), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 48/161 (29%), Positives = 82/161 (50%), Gaps = 6/161 (3%)
Frame = +1
Query: 45 PSTAIREISLLKELRHPNIVSLQDVLMQDSRLYLIFEFL-SMDLKKYLDSIPPGQYMDSS 103
P + E ++K+LRHP ++ L V QD +++I E + + L ++L G+ +
Sbjct: 64 PKDFLAEAQIMKKLRHPKLIQLYAVCTQDDPIFIITELMKNGSLLEFLQG--KGRVLKLP 237
Query: 104 LVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHE 163
+ QI G+ + S+ +HRDL +N+L+ D T+K+ADFGLAR I+ +E
Sbjct: 238 ALIDIGAQIACGMAYLESQNYIHRDLAARNILVSDNNTVKIADFGLARV----IKEDEYE 405
Query: 164 A-----ITLWYRSPEVLLGSARYSTPVDIWSIGTIFAELAT 199
A + + +PE R++ D+WS G + E T
Sbjct: 406 ARVGARFPIKWTAPEA-ANYNRFTIKSDVWSFGILLTETVT 525
>12453
Length = 680
Score = 75.9 bits (185), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 38/102 (37%), Positives = 57/102 (55%), Gaps = 1/102 (0%)
Frame = +3
Query: 190 IGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKN-TFPKWKPGS 248
+G IF E+A +PLF G + D+L IF+ LGTP + P + D+ P ++ +
Sbjct: 6 VGCIFYEMACGRPLFPGSTVEDELHLIFKTLGTPTEDSLPSISRNPDFLALNLPHYQGEA 185
Query: 249 LASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDL 290
L + LD +GLDLL+K L Y+ R+S +L H +FN L
Sbjct: 186 LITIAPRLDSDGLDLLAKFLKYNAKIRVSAADSLKHSFFNSL 311
>11780
Length = 1713
Score = 75.1 bits (183), Expect = 3e-14, Method: Compositional matrix adjust.
Identities = 49/148 (33%), Positives = 88/148 (59%), Gaps = 1/148 (0%)
Frame = +3
Query: 8 EKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQ 67
E IG+G +G VYKG ++ GQ VA+K+++ + E + ++E S++ LRH N+V L
Sbjct: 615 EAIGKGDFGDVYKGMYR--GQPVAIKQLKDKDRGE---QSFLQEASVMTSLRHDNLVRLI 779
Query: 68 DVLMQDSRLYLIFEFLSM-DLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCHSRRVLH 126
V++ ++ ++L+ EF+ +L +YL S + ++ + + S+R++H
Sbjct: 780 GVVLGET-IFLVTEFMGKGNLVEYLRSRGRSVITKKDQI-NFATDTCAAMEYLESKRLVH 953
Query: 127 RDLKPQNLLIDDKGTIKLADFGLARAFG 154
RDL +N+L+ D G K++DFGLA+ FG
Sbjct: 954 RDLAARNVLVHDDGKAKVSDFGLAK-FG 1034
>13066
Length = 551
Score = 74.7 bits (182), Expect = 4e-14, Method: Compositional matrix adjust.
Identities = 52/187 (27%), Positives = 86/187 (45%), Gaps = 7/187 (3%)
Frame = +3
Query: 12 EGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQDVLM 71
GT+ Y K +++ +K ++ E+ P RE+ LL +L HP I+ + +L
Sbjct: 21 HGTFNDGYGRNIKLACKIIDKEKAPVDFVEKFFP----RELDLLTKLDHPYIIQIHSILQ 188
Query: 72 QDSRLYLIFEFLSM-DLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCHSRRVLHRDLK 130
+ + ++ F DL Y+ + ++ K + YQ+ + + HS V HRDLK
Sbjct: 189 RXPKNFIFMRFAERGDLLTYIQEV---GFVKEKQAKIWFYQMTTALNYLHSYDVAHRDLK 359
Query: 131 PQNLLIDDKGTIKLADFGLARAF------GIPIRVYTHEAITLWYRSPEVLLGSARYSTP 184
+N+L+ +KLADFG A A R Y A Y +PE++ G+
Sbjct: 360 CENILLSSHFNVKLADFGFACACITESGEKYMSRTYCGSAA---YAAPEIVYGAPYAPKV 530
Query: 185 VDIWSIG 191
D WS+G
Sbjct: 531 ADAWSLG 551
>21433
Length = 590
Score = 58.2 bits (139), Expect(2) = 4e-12, Method: Compositional matrix adjust.
Identities = 37/96 (38%), Positives = 55/96 (57%)
Frame = +2
Query: 107 SYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEAIT 166
Y+YQ+ + +CH R+V+HRD+KP+NLL+ KG +K+ADFG + P T T
Sbjct: 179 CYIYQLSSALEYCHYRKVIHRDIKPENLLLGLKGDLKIADFGW--SVHAPSSRRTTMCGT 352
Query: 167 LWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKP 202
L Y PE++ G + VD+WS+G + E P
Sbjct: 353 LDYLPPEMVEGKT-HDENVDLWSLGVLCYEFLVGTP 457
Score = 30.0 bits (66), Expect(2) = 4e-12, Method: Compositional matrix adjust.
Identities = 14/33 (42%), Positives = 19/33 (57%)
Frame = +3
Query: 50 REISLLKELRHPNIVSLQDVLMQDSRLYLIFEF 82
REI + LRH NI+ + +R+YLI EF
Sbjct: 15 REIEIQSHLRHDNILRMFGYFHDKTRVYLILEF 113
>01392
Length = 1806
Score = 68.2 bits (165), Expect = 4e-12, Method: Compositional matrix adjust.
Identities = 56/189 (29%), Positives = 85/189 (44%), Gaps = 12/189 (6%)
Frame = -1
Query: 111 QILQGIVFCHSRRVLHRDLKPQNLL---IDDKGTIKLADFGLARAFGIPIR-VYTHEAIT 166
I + + F HS+ + HRDLKP+N+L +DD +K+ DF LA T E +T
Sbjct: 1767 HIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGISCDGDGTKTPELLT 1588
Query: 167 ----LWYRSPEVLLG----SARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFR 218
Y +PEV+ S Y D+WS+G I + P F+G D +
Sbjct: 1587 PVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILYIMLCGYPPFYGQCGEDCGWNRGE 1408
Query: 219 ALGTPNNEVWPEVESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISG 278
A + ++ S+QD FP + S++S K DL+ +L+ +P KR S
Sbjct: 1407 ACHDCQDMLF---NSIQDGHYKFPSQEWTSISSSAK-------DLIRHLLVREPRKRYSA 1258
Query: 279 KMALNHPYF 287
L HP+
Sbjct: 1257 ADVLKHPWI 1231
>31885
Length = 529
Score = 67.4 bits (163), Expect = 6e-12, Method: Compositional matrix adjust.
Identities = 49/175 (28%), Positives = 88/175 (50%), Gaps = 7/175 (4%)
Frame = -2
Query: 52 ISLLKELRHPNIVSLQDVLMQDSRLYLIFE-FLSMDLKKYLDSIPPGQYMDSSLVKSYLY 110
+ +L L HP +V+L + L+++ + FL DL+ ++ + VK YL
Sbjct: 519 VDMLTRLDHPFLVNLWYAFQDEEDLFMVVDLFLGGDLRYHMQQEVSFR---EDCVKFYLC 349
Query: 111 QILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEAITLWYR 170
Q+ + + S++++HRD+KP N+L+D++G + DF +A + T + T Y
Sbjct: 348 QLALVLDYLRSQKIVHRDIKPDNILLDEQGHCHVTDFNIATQLE-DDELATSTSGTRPYM 172
Query: 171 SPEVL---LGSAR-YSTPVDIWSIGTIFAELATKKPLF--HGDSEIDQLFRIFRA 219
+PEV + R Y PVD WS+G EL K+ F H ++ + +++ A
Sbjct: 171 APEVYGVAINERRGYGFPVDWWSLGVSLFELLKKRRPFSVHSNTSLHEMWATMVA 7
>18484
Length = 635
Score = 67.4 bits (163), Expect = 7e-12, Method: Compositional matrix adjust.
Identities = 48/171 (28%), Positives = 81/171 (47%), Gaps = 1/171 (0%)
Frame = +1
Query: 108 YLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEAI-T 166
Y +I G+ F H + +++RDLK N+++D +G IK+ADFG+ + G+ T T
Sbjct: 58 YAAEIAVGLFFLHDQGIIYRDLKLDNVMLDSEGHIKIADFGMCKE-GMTGDATTRTFCGT 234
Query: 167 LWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNE 226
Y +PE++L YS VD W+ G + E+ +P F G+ E D+LF
Sbjct: 235 PDYIAPEIVLYQP-YSKSVDWWAYGVLLFEMLAGQPPFDGEDE-DELF------------ 372
Query: 227 VWPEVESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRIS 277
S+ D+ ++P K + + L +L+ +P KR+
Sbjct: 373 -----SSITDHNVSYP-----------KAMSREAVSLCKGLLMKNPTKRLG 477
>27405
Length = 532
Score = 67.0 bits (162), Expect = 9e-12, Method: Compositional matrix adjust.
Identities = 52/179 (29%), Positives = 91/179 (50%), Gaps = 7/179 (3%)
Frame = -3
Query: 15 YGVVYKGRHKTTGQVVAMKKI-RLESEEEGVPSTAIREISLLKELR----HPNIVSLQDV 69
+G VY R TG++ AMK + + + +G + A+ E +L + P IV +
Sbjct: 527 FGEVYGCRKADTGKMYAMKCLDKKRIKMKGGETLALNERIMLSLVSTGEGSPFIVCMTYA 348
Query: 70 LMQDSRLYLIFEFLSM-DLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCHSRRVLHRD 128
+L I + ++ DL +L G + + V+ Y +++ G+ HSR V++RD
Sbjct: 347 FQTPEKLCFILDLMNGGDLHYHLSQ--HGVFTEKE-VRFYAAEVMLGLEHMHSRFVVYRD 177
Query: 129 LKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEAI-TLWYRSPEVLLGSARYSTPVD 186
LKP N+L+D+ G ++++D GLA F + H ++ T Y +PEVL+ Y + D
Sbjct: 176 LKPANILLDENGHVRISDLGLACDFS---KKKPHASVGTHGYMAPEVLMKGQAYDSSAD 9
>27546
Length = 426
Score = 67.0 bits (162), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 30/103 (29%), Positives = 59/103 (57%), Gaps = 1/103 (0%)
Frame = -1
Query: 50 REISLLKELRHPNIVSLQDVLMQDSRLYLIFEFLSM-DLKKYLDSIPPGQYMDSSLVKSY 108
RE+ +L L HPNI+ + +L + ++++ + D+ ++ P +D + K +
Sbjct: 333 RELEILTRLDHPNIIQIHSILQRGPKIFIFMRYAEKGDMLSHIKKTGP---IDEAQTKVW 163
Query: 109 LYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLAR 151
+Q+ + + + HS + HRDLK +N+L+ + +K+ADFG AR
Sbjct: 162 FFQMAKALQYLHSHDIAHRDLKCENILLSKRLNVKIADFGFAR 34
>18287
Length = 678
Score = 65.9 bits (159), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 37/112 (33%), Positives = 60/112 (53%), Gaps = 3/112 (2%)
Frame = -3
Query: 181 YSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNE-VWPEVESLQDY-- 237
Y +DIWS+G IFAEL +++ LF + QL I +GTP E + E +++
Sbjct: 673 YDYSIDIWSVGCIFAELLSRRILFQAQGPVQQLDMIINLVGTPRPEDMERACEGARNHIL 494
Query: 238 KNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFND 289
F + +L + + + LL++MLI +P RIS + AL+HPY ++
Sbjct: 493 NQPFRRQNLLTLYNLSPHATHEAVRLLTRMLILNPKNRISAEEALSHPYLDE 338
>00392
Length = 668
Score = 65.1 bits (157), Expect = 3e-11, Method: Compositional matrix adjust.
Identities = 51/175 (29%), Positives = 89/175 (50%), Gaps = 10/175 (5%)
Frame = +3
Query: 51 EISLLKELRHPNIVSLQDVLMQDSR-----LYLIFEFL-SMDLKKYLDSIPPGQYMDSSL 104
E +LKEL+HPNIV D + + + L+ E + S LK YL + + +
Sbjct: 81 EAEMLKELQHPNIVRFFDYWEEHNHRNRKVIILVTELMTSGTLKTYLKRF---KKPNVKI 251
Query: 105 VKSYLYQILQGIVFCHSRR--VLHRDLKPQNLLIDD-KGTIKLADFGLARAFGIPIRVYT 161
+K++ Q+L+G+ F H+R V+HRDLK N+ I G++K+ D GLA + + +
Sbjct: 252 LKNWCRQVLKGLYFLHTRTPPVIHRDLKCDNIFITGPTGSVKIGDLGLA---TLKNQSFA 422
Query: 162 HEAI-TLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFR 215
I T + +PE+ Y VD+++ G E+A+ + + S Q+++
Sbjct: 423 KSVIGTPEFMAPEMY--EEHYDEAVDVYAFGMCMLEMASSEYPYSECSNAAQIYK 581
>26560
Length = 398
Score = 65.1 bits (157), Expect = 4e-11, Method: Compositional matrix adjust.
Identities = 37/114 (32%), Positives = 63/114 (55%), Gaps = 5/114 (4%)
Frame = -1
Query: 105 VKSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEA 164
V+ Y +++ G+ HSR V++RDLKP N+L+D+ G ++++D GLA F + H +
Sbjct: 350 VRFYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGLACDFS---KKRPHAS 180
Query: 165 I-TLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLF----HGDSEIDQL 213
+ T Y +PEVL+ Y + D +S G + +L F G + ID++
Sbjct: 179 VGTHGYMAPEVLMKGQSYDSSADWFSFGCMLYKLLKGHSPFRQHNQGQARIDRM 18
>30755
Length = 1137
Score = 63.9 bits (154), Expect = 6e-11, Method: Compositional matrix adjust.
Identities = 54/196 (27%), Positives = 89/196 (45%), Gaps = 9/196 (4%)
Frame = +2
Query: 105 VKSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLAR---AFGIPIRVYT 161
+ Y +I+ + + HS+ +++RDLK +NLL+D G IK+ADFGL + +G + +
Sbjct: 38 TRFYGAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCKEDITYGRTTKTFC 217
Query: 162 HEAITLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKK-PLFHGDSEIDQLFRIFRAL 220
T Y +PEV L Y VD W G + E+ + P ++ D ++ LF +
Sbjct: 218 G---TPEYLAPEV-LDDNDYGRAVDWWGTGVVMYEMICGRLPFYNRDHDV--LFTLIL-- 373
Query: 221 GTPNNEVWPEVESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISG-- 278
++D K FP +N+ + LLS +L DP R+ G
Sbjct: 374 -------------VEDVK--FP-----------RNITDEAKSLLSGLLAKDPRNRLGGGQ 475
Query: 279 ---KMALNHPYFNDLD 291
K HP+F ++
Sbjct: 476 DDVKEIQAHPFFASIN 523
>19094
Length = 898
Score = 63.5 bits (153), Expect = 9e-11, Method: Compositional matrix adjust.
Identities = 34/94 (36%), Positives = 54/94 (57%)
Frame = +1
Query: 105 VKSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEA 164
+ + LY L+G+ + HSRR +HRD+K N+L++++G KLADFG+A +
Sbjct: 64 IATILYYTLKGL*YLHSRRKIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVI 243
Query: 165 ITLWYRSPEVLLGSARYSTPVDIWSIGTIFAELA 198
T ++ +PEV+ Y DIWS+G E+A
Sbjct: 244 GTPYWMAPEVIQ-EIGYDCVADIWSLGITALEMA 342
>14477
Length = 493
Score = 61.6 bits (148), Expect = 4e-10, Method: Compositional matrix adjust.
Identities = 40/148 (27%), Positives = 80/148 (54%), Gaps = 3/148 (2%)
Frame = -1
Query: 9 KIGEGTYGVVYKGRHKTTGQV--VAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSL 66
K+G G +G V KG + + VA+K ++ + V S I+E ++K++ H +IV L
Sbjct: 469 KLGAGNFGSVMKGVCRLDDREIPVAIKVLKNADLDPSVQSELIKEAEVMKKMDHMHIVRL 290
Query: 67 QDVLMQDSRLYLIFEFLSMD-LKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCHSRRVL 125
L + + L+ E + L K+L P +++ + ++Q+ QG+ + + + +
Sbjct: 289 IG-LCEGETMMLVLELAKLGPLNKFL---PKNKHLPLWNILELMWQVSQGMEYLEANKFV 122
Query: 126 HRDLKPQNLLIDDKGTIKLADFGLARAF 153
HRDL +N+L+ D+ K++DFG+++
Sbjct: 121 HRDLAARNILLCDEHFAKISDFGMSKTL 38
>26909
Length = 394
Score = 61.2 bits (147), Expect = 4e-10, Method: Compositional matrix adjust.
Identities = 36/113 (31%), Positives = 52/113 (46%), Gaps = 18/113 (15%)
Frame = +2
Query: 193 IFAELATKKPLFHGDSEI---------DQLFRIFRALGTPNNEVWPEVESLQDYKNTFPK 243
IFAEL T +P+FH E DQL RIF +G P + W ++ + +++
Sbjct: 2 IFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFPQEKDWEDIRRMPEHQQLTKD 181
Query: 244 WKPGS---------LASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYF 287
+K S + H D LL K+L DP KRI+ + A+ PYF
Sbjct: 182 FKRSSYVNCNLMKYMEKHKVKADSKAFHLLQKLLTMDPVKRITSEQAMKDPYF 340
>13212
Length = 1067
Score = 60.5 bits (145), Expect = 7e-10, Method: Compositional matrix adjust.
Identities = 50/193 (25%), Positives = 80/193 (41%), Gaps = 5/193 (2%)
Frame = -1
Query: 100 MDSSLVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRV 159
M + + +++ + F H V+HRD+K N+L+ G +KLADFG++ +
Sbjct: 989 MTEAQICYVCHEMCMALDFLHRHHVIHRDIKAGNVLLTIDGEVKLADFGVSAKNTQTQQK 810
Query: 160 YTHEAITLWYRSPEVLLGSARYSTP----VDIWSIGTIFAELATKKPLFHGDSEIDQLFR 215
T ++ +PEV+L TP DIWS+G E A +P
Sbjct: 809 RDTFIGTPYWMAPEVVLCETLKDTPYDFKADIWSLGVTLIEFAQIEP------------- 669
Query: 216 IFRALGTPNNEVWPEVESLQDYKNTFPKW-KPGSLASHVKNLDENGLDLLSKMLIYDPAK 274
PN E+ P ++ +K+ P KP K D ++K L+ DP
Sbjct: 668 -------PNKEMHPMRVLIKIHKSDPPTLEKPKKWTKLFK-------DFIAKCLVKDPNL 531
Query: 275 RISGKMALNHPYF 287
R + L HP+
Sbjct: 530 RPTAAELLEHPFM 492
>14116
Length = 1017
Score = 60.5 bits (145), Expect = 8e-10, Method: Compositional matrix adjust.
Identities = 51/210 (24%), Positives = 97/210 (46%), Gaps = 14/210 (6%)
Frame = -1
Query: 5 TKIEKIGEGTYGVVYKGRHKTTGQ----VVAMKKIRLESEEEGVPSTAIREISLLKELRH 60
T E+IG+G +G V +G Q +VA+K + + E + ++E ++K+ H
Sbjct: 627 TMGEEIGKGNFGCVKRGFLTLPEQKGDILVAVKTLHNNNPREIELQSFLQEALIMKDFHH 448
Query: 61 PNIVSLQDVLMQ-DSRLYLIFEFLSM-DLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVF 118
N+++L + + D ++ F+ DL Y+ + ++ Y I +G+ +
Sbjct: 447 SNVLTLIGICLNLDDMPLVVLPFMKHGDLLTYIRDDQHQPTIKDLIM--YGVDIARGMDY 274
Query: 119 CHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEAITLWYRSPEV---- 174
+ +HRDL +N ++D+ +K+ADFGLAR +Y E + + ++
Sbjct: 273 LAGLKFVHRDLAARNCMLDEDFHVKVADFGLAR------DIYEKEYYSSENKKAKLPVKW 112
Query: 175 ----LLGSARYSTPVDIWSIGTIFAELATK 200
L Y + D+WS G + EL T+
Sbjct: 111 MALESLEKGNYDSKTDVWSYGVVLWELLTR 22
>17253
Length = 483
Score = 59.7 bits (143), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 36/134 (26%), Positives = 68/134 (50%), Gaps = 11/134 (8%)
Frame = -1
Query: 38 ESEEEGVPSTAIREISLLKEL-RHPNIVSLQDVLMQDSRLYLIFEFLSM-DLKKYLDSIP 95
E+ + S +RE+S++++L RHPN+VS ++ EF DL +L
Sbjct: 438 EAATDAEKSEFLRELSIMRKLPRHPNVVSFMGCCTMSDPALILMEFCCHGDLLSFLRKRR 259
Query: 96 PGQ--YMDSSLVK-------SYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLAD 146
P + ++ S+ S+ + +G+ + +++HRD+ +N+LI ++ K++D
Sbjct: 258 PDRTVFLTSTANDLTARDFFSFALHVARGMAHVANNKIVHRDVAARNVLISERNVCKVSD 79
Query: 147 FGLARAFGIPIRVY 160
FGL+R G VY
Sbjct: 78 FGLSRRVGDQNDVY 37
>07940
Length = 1336
Score = 59.3 bits (142), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 31/95 (32%), Positives = 55/95 (57%), Gaps = 2/95 (2%)
Frame = -3
Query: 107 SYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGI--PIRVYTHEA 164
SY YQ+ +G+ + S++ +HRDL +N+L+ ++ +K+ADFGL R R T
Sbjct: 335 SYAYQVARGMEYLASKQCIHRDLAARNVLVAEEYVLKIADFGLTRNLQQFDYYRKTTDGR 156
Query: 165 ITLWYRSPEVLLGSARYSTPVDIWSIGTIFAELAT 199
+ + + +PE L +Y++ D+WS G + E+ T
Sbjct: 155 LPVKWMAPEALF-DRKYTSKSDVWSYGVLLWEIFT 54
>31489
Length = 329
Score = 58.9 bits (141), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 33/90 (36%), Positives = 57/90 (63%), Gaps = 6/90 (6%)
Frame = +3
Query: 52 ISLLKELRHPNIVSLQDVLM-QDS-----RLYLIFEFLSMDLKKYLDSIPPGQYMDSSLV 105
I +LK +H NI+S++++L +DS ++++F+ + DL + + S P + +
Sbjct: 3 IKILKHFKHDNIISIREILKPKDSYHDFKDIHVVFDLMESDLHRIIYSDQP---LTEEHI 173
Query: 106 KSYLYQILQGIVFCHSRRVLHRDLKPQNLL 135
+ +LYQIL+G+ + HS V+HRDLKP NLL
Sbjct: 174 RYFLYQILRGLKYIHSANVVHRDLKPSNLL 263
>26711
Length = 405
Score = 55.8 bits (133), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 36/105 (34%), Positives = 54/105 (51%), Gaps = 2/105 (1%)
Frame = -2
Query: 111 QILQGIVFCHSRRVLHRDLKPQNLLI--DDKGTIKLADFGLARAFGIPIRVYTHEAITLW 168
Q+L + H++ V+H DLKP NLL+ D +++L DFGLAR P + + T
Sbjct: 392 QVLDILQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARKLYPPQETFLNHG-TPG 216
Query: 169 YRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQL 213
+ SPE L ST D+W +G + L + + F DS + L
Sbjct: 215 FTSPEA-LDVKPISTASDVWGVGVLAYILLSGQSPFQADSATESL 84
>18401
Length = 463
Score = 55.8 bits (133), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 49/145 (33%), Positives = 67/145 (46%), Gaps = 22/145 (15%)
Frame = -3
Query: 166 TLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALG---- 221
T YR+PEV+L +S P D+WS+G I EL T LF + L + R LG
Sbjct: 443 TRHYRAPEVILELG-WSHPCDVWSVGCIMFELYTGYTLFQTHDNKEHLAMMERILGSLPY 267
Query: 222 -----TPNNEVW-------PEVESLQDY--KNTFPKWKPGSLASHVK---NLDENGL-DL 263
T + + PE S+ Y +NT P L +VK N D L DL
Sbjct: 266 RMAKKTKKQKYFHHGRLDVPERSSMARYVRENTKP------LLRYVKDRENKDHQQLFDL 105
Query: 264 LSKMLIYDPAKRISGKMALNHPYFN 288
+ K+L Y+ + R S AL HP+F+
Sbjct: 104 MKKLLAYEASSRYSLLQALQHPFFS 30
>28157
Length = 400
Score = 55.5 bits (132), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 42/126 (33%), Positives = 66/126 (52%), Gaps = 5/126 (3%)
Frame = +3
Query: 30 VAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQDVLMQDSRLYLIFEFL-SMDLK 88
VA+K R+ESE+E + ++E+ L + HPNIV L +D + L+ E+ L
Sbjct: 9 VAVK--RIESEQE--KKSFMQELKQLSRVSHPNIVCLYGAC-RDHPVCLVMEYAEGGSLY 173
Query: 89 KYLDSIPPGQYMDSSLVKSYLYQILQGIVFCHS---RRVLHRDLKPQNLLIDDKGT-IKL 144
L P ++ ++L Q G+ + H + ++HRDLKP NLL+ GT +K+
Sbjct: 174 NVLHGSGPQPQYTAAHAMNWLLQCALGVEYLHGMKPKALIHRDLKPPNLLLIQCGTKLKI 353
Query: 145 ADFGLA 150
DFG A
Sbjct: 354 CDFGTA 371
>32359
Length = 928
Score = 45.8 bits (107), Expect(2) = 4e-08, Method: Compositional matrix adjust.
Identities = 32/129 (24%), Positives = 63/129 (48%), Gaps = 7/129 (5%)
Frame = -1
Query: 4 YTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNI 63
YT + IG G++GVVY+ + T ++VA+KK+ + + RE+ ++++L H NI
Sbjct: 424 YTDAKVIGNGSFGVVYQAKLVDTSELVAIKKVLQDKRFKN------RELQIMRKLEHQNI 263
Query: 64 VSLQDVLMQDSR------LYLIFEFLSMDLKKYLDSIPPG-QYMDSSLVKSYLYQILQGI 116
V L+ L L+ E++ + + Q + +K Y+YQ+ + +
Sbjct: 262 VKLKFFFYSSGEKKDEVFLNLVLEYVPETVYRVARHYSKSKQTIPILYIKLYMYQLFRSL 83
Query: 117 VFCHSRRVL 125
+ HS+ +
Sbjct: 82 AYIHSQACV 56
Score = 28.5 bits (62), Expect(2) = 4e-08, Method: Compositional matrix adjust.
Identities = 11/14 (78%), Positives = 13/14 (92%)
Frame = -3
Query: 124 VLHRDLKPQNLLID 137
V HRD+KPQNLL+D
Sbjct: 62 VCHRDIKPQNLLLD 21
>22005
Length = 873
Score = 54.7 bits (130), Expect = 5e-08, Method: Compositional matrix adjust.
Identities = 65/242 (26%), Positives = 96/242 (39%), Gaps = 54/242 (22%)
Frame = +1
Query: 10 IGEGTYGVVYK----GRHKTTGQVVAMK------KIRLESEEEGVPSTAIREISLLKELR 59
IG+G +G V K G G+++ K K+ E E + S RE SL+ +
Sbjct: 7 IGQGAFGRVSKLKFLGLASLVGELIPEKRP*LL*KMLKEDASEDLQSDFEREASLMADFD 186
Query: 60 HPNIVSLQDVLMQDSRLYLIFEFLSM-DLKKYLDSIPPGQY------------------- 99
HPNIV L V + L+FEF+S DL +L P Y
Sbjct: 187 HPNIVKLLGVCAIGKPMCLLFEFMSKGDLNDFLRLCSPENYNLPVSRSQNLVVDLEDGLR 366
Query: 100 ----------------MDSS---LVKSYLY---QILQGIVFCHSRRVLHRDLKPQNLLID 137
D S K LY QI G+ + + +HRDL + +
Sbjct: 367 VEVEAEECEKDTQSEDRDCSGMLXTKDQLYISQQISAGMAYLAQKDYVHRDLATRTVXS- 543
Query: 138 DKGTIKLADFGLARAFGIP--IRVYTHEAITLWYRSPEVLLGSARYSTPVDIWSIGTIFA 195
++DFGLAR+ R +AI + + E +L S ++ST D+WS G +
Sbjct: 544 RTT*S*ISDFGLARSVHSVDYYRGSEQDAIPIRWMPLEAILYS-KFSTQSDVWSFGVVLW 720
Query: 196 EL 197
E+
Sbjct: 721 EI 726
>00715
Length = 1788
Score = 54.3 bits (129), Expect = 6e-08, Method: Compositional matrix adjust.
Identities = 49/175 (28%), Positives = 88/175 (50%), Gaps = 26/175 (14%)
Frame = +1
Query: 58 LRHPNIVSL---QDVLMQDSRLYLIFEFLS-MDLKKYLDSIPPGQYMDSSLVKSYLYQIL 113
LRH N+VS+ + + +L E++ ++L+ L+ Q +DSS+ S Q+
Sbjct: 97 LRHVNVVSILGATSLHRFEDGAWLAMEYVGPLNLQTILND--HQQDIDSSMRLSLALQMA 270
Query: 114 QGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLA------------RAFGI------ 155
+G+ + HS ++H DLKP N L+ +++ADFG R G+
Sbjct: 271 RGLHYLHSINIVHLDLKPANCLLTRDLKLRIADFGCCHQLTPTGLDMGEREGGMAGNELE 450
Query: 156 --PIR-VYTHE-AITLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHG 206
P++ + +E A TL YR+PE+L G + S D++S+G ++ T++ + G
Sbjct: 451 LTPVQGAWKNELAGTLAYRAPELLKG-LQPSVRSDVYSLGITLWQMCTRQGPYEG 612
>21079
Length = 878
Score = 53.9 bits (128), Expect = 7e-08, Method: Compositional matrix adjust.
Identities = 42/141 (29%), Positives = 69/141 (48%), Gaps = 7/141 (4%)
Frame = +1
Query: 60 HPNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFC 119
HP ++ L D + L+ EF+ + + I + ++ QI G+ +
Sbjct: 1 HPKLLMLWDAFEAPRTMVLVMEFVGAG-ELFERVIRDDFVLTERDCVHFVRQICSGVGYM 177
Query: 120 HSRRVLHRDLKPQNLLI--DDKGTIKLADFGLARAF----GIPIRVYTHEAITLWYRSPE 173
H++ +LH DLKP+N+L D+ IK+ DFGLAR + + + T E I +PE
Sbjct: 178 HTQSILHLDLKPENVLCVSDNSNQIKIIDFGLARFYKPGDSLQVLFGTPEFI-----APE 342
Query: 174 VL-LGSARYSTPVDIWSIGTI 193
V+ ++T D+WSIG I
Sbjct: 343 VVNYDEINFTT--DMWSIGVI 399
>11185
Length = 473
Score = 50.8 bits (120), Expect = 7e-07, Method: Compositional matrix adjust.
Identities = 32/115 (27%), Positives = 53/115 (46%), Gaps = 22/115 (19%)
Frame = +1
Query: 105 VKSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIR---VYT 161
++ + ++ G+ + HS +L DL+P +L+D G +K ADFGL++ G +
Sbjct: 7 IRDFGIHLVTGLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKF 186
Query: 162 HEAITLW-------------------YRSPEVLLGSARYSTPVDIWSIGTIFAEL 197
EA W Y +PEV G A S D+W++G +F E+
Sbjct: 187 AEAGDQWNIQSAEEMMKQVPTSGSPTYMAPEVFQG-AEPSIMSDLWALGCVFYEM 348
>16708
Length = 1397
Score = 50.4 bits (119), Expect = 8e-07, Method: Compositional matrix adjust.
Identities = 46/207 (22%), Positives = 87/207 (42%), Gaps = 15/207 (7%)
Frame = -1
Query: 7 IEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH----PN 62
++ +G+G +G VY+ R +T + A+K L ++ E+ L +
Sbjct: 1388 LQVLGKGVFGKVYEARLLSTHEKAALKTSILCHH-------SLDEVEALGRIEGGFYLAQ 1230
Query: 63 IVSLQDVLMQDSRLYLIFEFLSMD-----LKKYLDSIPPGQYMDSSLVKSYLYQILQGIV 117
+ + ++ ++ F M Y + P ++ + ++V Q + +
Sbjct: 1229 MFGAWVTCLPFPKMNILLHFYEMGPLCNVYAHYKNKEMPIRWSNPAMVCCIAGQXVCALE 1050
Query: 118 FCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGI-PIRVYTHEA-----ITLWYRS 171
H V+H D+K N+L+D G KL D+G+A+ + + P TH + T + R
Sbjct: 1049 HIHELGVVHMDVKADNVLVDAHGNCKLTDYGIAQLYKVYPAPTETHSSGCTNKRTFYTRP 870
Query: 172 PEVLLGSARYSTPVDIWSIGTIFAELA 198
P + S R+S D IGT + L
Sbjct: 869 PATMTPSERFSEEGD--GIGTDYFRLG 795
>13840
Length = 446
Score = 48.5 bits (114), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 38/133 (28%), Positives = 65/133 (48%), Gaps = 5/133 (3%)
Frame = -1
Query: 2 EDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHP 61
ED + +IG G YG V K RHK T V+A+K+IR EE + +++ P
Sbjct: 395 EDMQDMGEIGRGNYGTVNKMRHKITSTVMAVKRIRSTVEEREQKQLLMDLDVVMRSNNCP 216
Query: 62 NIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQI----LQGIV 117
IV L ++ ++ E + L K+ + G+ M SS+ ++ L +I L+ +
Sbjct: 215 FIVQFYGALFKEGDCWICMELMETSLDKFYKFV-YGE-MQSSIPENILGKITVATLKALN 42
Query: 118 FCHSR-RVLHRDL 129
+ R++HRD+
Sbjct: 41 YLKEELRIIHRDV 3
>07291
Length = 833
Score = 48.5 bits (114), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 34/144 (23%), Positives = 66/144 (45%), Gaps = 8/144 (5%)
Frame = +1
Query: 111 QILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHE-----AI 165
QI G+ + +V+HR+L +N ++ + G ++L+D+G+ + P YT + +
Sbjct: 73 QIADGMAYLQEVKVVHRNLAARNCIVTEDGRLQLSDYGVTGSL-FPQSYYTADDSPARDL 249
Query: 166 TLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRA---LGT 222
W +PE + + +S+ D+W+ G + EL T+ + D E L + +
Sbjct: 250 VKWM-APET-IDNFHFSSKSDVWAFGVVLWELLTRGITPYPDVENSSLLPYLKEGHRMKK 423
Query: 223 PNNEVWPEVESLQDYKNTFPKWKP 246
P P E + N P+ +P
Sbjct: 424 PKQSPEPVYEMMTACWNESPEQRP 495
>01106
Length = 878
Score = 48.1 bits (113), Expect = 5e-06, Method: Compositional matrix adjust.
Identities = 41/148 (27%), Positives = 73/148 (49%), Gaps = 15/148 (10%)
Frame = +3
Query: 4 YTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNI 63
Y I K+G G + V+ T + VA+K ++ + TA+ E+ LLK +R ++
Sbjct: 324 YHVIRKLGWGHFSTVWLCWDLTCKRFVALKVVK---SAQHYTETALDEVKLLKCVRESDV 494
Query: 64 --------VSLQDVL----MQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSL--VKSYL 109
V L D + + + ++FE L +L L I Y + VK +
Sbjct: 495 ADPARAKCVQLLDDFKISGVNGTHVAMVFEVLGYNL---LKLIIRSNYQGIPIHNVKLII 665
Query: 110 YQILQGIVFCHSR-RVLHRDLKPQNLLI 136
Q+L+G+ + H++ R++H D+KP+N+LI
Sbjct: 666 RQVLEGLSYMHAKCRIIHTDIKPENILI 749
>16003
Length = 926
Score = 47.8 bits (112), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 33/88 (37%), Positives = 46/88 (52%)
Frame = -1
Query: 202 PLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNTFPKWKPGSLASHVKNLDENGL 261
P GD+++DQL +IF LGTP WP V SL DY F + L ++ L
Sbjct: 911 PFLPGDTDLDQLGKIFNMLGTPTETEWPAVTSLPDYIQ-FKHCQKQPLKEIFTAAGDDLL 735
Query: 262 DLLSKMLIYDPAKRISGKMALNHPYFND 289
+LL K+L +P R + AL PYF++
Sbjct: 734 ELLDKLLAMNPLHRCTATQALKMPYFSN 651
>20640
Length = 1492
Score = 47.0 bits (110), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 27/78 (34%), Positives = 44/78 (56%), Gaps = 2/78 (2%)
Frame = +1
Query: 122 RRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIP--IRVYTHEAITLWYRSPEVLLGSA 179
R +HRDL +N L+ +K++DFGLAR+ R H+AI + + E +L +
Sbjct: 1 RGYVHRDLATRNCLVGHDLVVKISDFGLARSVHSVDYYRGSEHDAIPIRWMPLEAILYN- 177
Query: 180 RYSTPVDIWSIGTIFAEL 197
++ST D+WS G + E+
Sbjct: 178 KFSTQSDVWSFGVVLWEI 231
>13078
Length = 773
Score = 47.0 bits (110), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 36/126 (28%), Positives = 55/126 (43%), Gaps = 16/126 (12%)
Frame = -1
Query: 181 YSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNT 240
+S P D+WSIG I EL T LF + L + R LG+ + + + + + +
Sbjct: 746 WSQPCDVWSIGCIMFELYTGYTLFQTHDNKEHLAMMERILGSLPYRMAKKTKKQKYFYHG 567
Query: 241 FPKWKPGSLAS------------HVKNLDENG----LDLLSKMLIYDPAKRISGKMALNH 284
W S A +VK+ D DL+ KML Y+ + R S + A+ H
Sbjct: 566 RLDWDEKSSAGRYVRDNVKPLRRYVKDPDNEDHQQLFDLMDKMLSYEVSTRYSLRQAMRH 387
Query: 285 PYFNDL 290
P+F L
Sbjct: 386 PFFRKL 369
>36481
Length = 806
Score = 46.2 bits (108), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 36/134 (26%), Positives = 61/134 (45%), Gaps = 6/134 (4%)
Frame = +2
Query: 11 GEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPN------IV 64
GEGT+G V + + G +A+K I+ + A EI++L++LR + V
Sbjct: 389 GEGTFGKVVQCKDLLKGDDIALKIIK---NVDKYREAAKLEINVLEKLREKDPHAKHMCV 559
Query: 65 SLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCHSRRV 124
+ D + + F L + + +L G Y V+ YQ+ + F H ++
Sbjct: 560 QMLDWFDYHGHVCISFHMLGLSVFDFLKDNSYGAY-PIEQVRHISYQLCYAVNFLHENQL 736
Query: 125 LHRDLKPQNLLIDD 138
H DLKP+N+L D
Sbjct: 737 THTDLKPENILFVD 778
>12786
Length = 460
Score = 45.8 bits (107), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 35/138 (25%), Positives = 61/138 (44%), Gaps = 22/138 (15%)
Frame = -3
Query: 98 QYMDSSLVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPI 157
Q +D ++K Y ++L+ + H+ V+H DLKP N ++ G +KL DFG+A
Sbjct: 425 QGLDRMMIKFYWREMLRAVKALHNEGVIHSDLKPANFML-VAGNLKLIDFGIANTLQQDK 249
Query: 158 RVYTHEAI--TLWYRSPEVLLGSA-----------------RYSTPV--DIWSIGTIFAE 196
++ T Y SPE ++ + +Y V D+WS+G I
Sbjct: 248 TSVLKDSRVGTPSYMSPEAIMAACDDSADDSMEEDGHRTKPKYKVGVRSDVWSLGCILYN 69
Query: 197 LA-TKKPLFHGDSEIDQL 213
+ + P H + + +L
Sbjct: 68 MVYGRTPFQHIKNNMGKL 15
>18996
Length = 491
Score = 45.8 bits (107), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 26/79 (32%), Positives = 46/79 (58%), Gaps = 3/79 (3%)
Frame = +2
Query: 125 LHRDLKPQNLLIDDKGTIKLADFGLAR---AFGIPIRVYTHEAITLWYRSPEVLLGSARY 181
+HRDL +N+L+D + +K++DFGLA+ A G + + WY SPE + + ++
Sbjct: 2 IHRDLAARNILVD-RSCVKISDFGLAQFANADGYYYGISQRDIPIKWY-SPEA-IETCKF 172
Query: 182 STPVDIWSIGTIFAELATK 200
S+ D+WS G E+ ++
Sbjct: 173 SSYSDVWSYGVTLFEMFSR 229
>11404
Length = 563
Score = 45.4 bits (106), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 40/135 (29%), Positives = 70/135 (51%), Gaps = 8/135 (5%)
Frame = +1
Query: 10 IGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKEL-RHPN-----I 63
IG+G++G V K T + VA+K I+ ++ + A E+ LL+ + RH I
Sbjct: 163 IGKGSFGQVVKAYDHTDNEQVAIKIIK---NKKPFLNQAQIEVKLLEMMNRHDTDNKYYI 333
Query: 64 VSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCHS-- 121
V L+ M S L L+FE LS +L L + + + +L + + Q+ ++F +
Sbjct: 334 VRLKRHFMFRSHLCLVFELLSYNLYDLLRN-TNFRGVSLNLTRKFAQQLCTALLFLATPE 510
Query: 122 RRVLHRDLKPQNLLI 136
++H DLKP+N+L+
Sbjct: 511 MSIIHCDLKPENILL 555
>06358
Length = 1517
Score = 43.9 bits (102), Expect = 7e-05, Method: Compositional matrix adjust.
Identities = 71/320 (22%), Positives = 129/320 (40%), Gaps = 33/320 (10%)
Frame = +3
Query: 4 YTKIEKIGEGTYGVVYKGRHKTT---GQVVAMKKIRLES----EEEGVPSTAIREISLLK 56
Y ++ G G V+ K+T V +K ++ + E + + L
Sbjct: 12 YNQVASAGPGLLWKVFAASKKSTKEEASVFVFEKKSVDRYSRRDREAIVEVLRVGVQQLT 191
Query: 57 ELRHPNIVSLQDVLMQDSRLYLIFE----FLSM-DLKKYLDSIP--PGQYMDSSL----V 105
+LRHP I+++ + L ++SR L F F S+ ++ L SI P + D L +
Sbjct: 192 KLRHPKILAVINPL-EESRETLAFATEPVFASLANVLGDLSSIXTVPKELQDYQLYDVEI 368
Query: 106 KSYLYQILQGIVFCHS-RRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEA 164
K L Q+ + + F H+ +++HR++ P+ +++ G+ KLA + P
Sbjct: 369 KHGLLQVTEALGFLHNDAKMMHRNVCPEAIMLTKLGSWKLAGYEFCVRSSDPQSTDPSYP 548
Query: 165 ITLW-------------YRSPEVLLGSARYSTPVDIWSIG-TIFAELATKKPLFHGDSEI 210
W + +PE +L + + T D++S+G +++ A KPLF + E+
Sbjct: 549 FYEWRSDIAPVTQPHLDFMAPEYVL-TMQCGTGSDMFSLGLLVYSVFAKGKPLFECNGEL 725
Query: 211 DQLFRIFRALGTPNNEVWPEVESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIY 270
F++ E L+ + + P L HVK L L
Sbjct: 726 SA----FKS----------NAEELRHMRVSLLGVVPEDLRDHVKLL-----------LNI 830
Query: 271 DPAKRISGKMALNHPYFNDL 290
+PA R P+F D+
Sbjct: 831 EPAVRPDAAQLSKVPFFEDV 890
>05084
Length = 1324
Score = 43.5 bits (101), Expect = 9e-05, Method: Compositional matrix adjust.
Identities = 30/95 (31%), Positives = 50/95 (52%), Gaps = 3/95 (3%)
Frame = +2
Query: 206 GDSEIDQLFRIFRALGTPNNEVWPEVE-SLQDYKNTFPKWK--PGSLASHVKNLDENGLD 262
GDS +DQL I + LGTP E E+ + ++K FP+ K P + + E +
Sbjct: 8 GDSGVDQLVEIIKVLGTPTREQIREMNPNYSEFK--FPQIKAHPWTKVFRPRTPPE-AIQ 178
Query: 263 LLSKMLIYDPAKRISGKMALNHPYFNDLDNQIKKM 297
L+S++L Y P+ RI A H +F++L + ++
Sbjct: 179 LVSRLLEYTPSARIQPMEACAHAFFDELRDPASRL 283
>26156
Length = 479
Score = 41.6 bits (96), Expect(2) = 1e-04, Method: Compositional matrix adjust.
Identities = 23/86 (26%), Positives = 43/86 (50%), Gaps = 2/86 (2%)
Frame = -1
Query: 1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLE--SEEEGVPSTAIREISLLKEL 58
+ D+ + IG G+Y V + HK T ++ AMK I+ E +++E + +
Sbjct: 392 LTDFLLLRVIGRGSYAKVLQVEHKRTKRIYAMKVIKKELVNDDEDIDWVQTEKHVFETAT 213
Query: 59 RHPNIVSLQDVLMQDSRLYLIFEFLS 84
+P +V L +SRL+ + EF++
Sbjct: 212 NYPFLVGLHSCFQSESRLFFVIEFVN 135
Score = 21.2 bits (43), Expect(2) = 1e-04, Method: Compositional matrix adjust.
Identities = 9/23 (39%), Positives = 14/23 (60%)
Frame = -3
Query: 108 YLYQILQGIVFCHSRRVLHRDLK 130
Y +I + F H R +++RDLK
Sbjct: 72 YSAEICLALNFLHKRGIVYRDLK 4
>16350
Length = 1108
Score = 43.1 bits (100), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 31/80 (38%), Positives = 41/80 (51%), Gaps = 3/80 (3%)
Frame = +2
Query: 128 DLKPQNLLIDDKGT---IKLADFGLARAFGIPIRVYTHEAITLWYRSPEVLLGSARYSTP 184
D KP+ +++ T +K+AD G A +T + T YR EVL+G A Y TP
Sbjct: 305 DNKPECDPVNEICTDFPVKIADLGNAC---WTYHHFTEDIQTRQYRCLEVLIG-AGYGTP 472
Query: 185 VDIWSIGTIFAELATKKPLF 204
DIWS + ELAT LF
Sbjct: 473 ADIWSTACMAFELATGDYLF 532
Score = 30.0 bits (66), Expect = 1.2, Method: Compositional matrix adjust.
Identities = 10/27 (37%), Positives = 16/27 (59%)
Frame = +3
Query: 262 DLLSKMLIYDPAKRISGKMALNHPYFN 288
D L+ ML +DP +R + +L HP+
Sbjct: 762 DFLAPMLEFDPEQRATAAQSLQHPWLK 842
>17300
Length = 480
Score = 42.4 bits (98), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 27/97 (27%), Positives = 48/97 (49%), Gaps = 16/97 (16%)
Frame = +1
Query: 125 LHRDLKPQNLLIDDKGTIKLADFGLARAF--------------GIPIRVYTHEAITLWYR 170
+HRDL +N+L+++ K+ADFGL+R IP+R EAI YR
Sbjct: 40 VHRDLAARNILVNEILVCKVADFGLSREIESDTTEGAYTTKGGKIPVRWTAPEAIA--YR 213
Query: 171 SPEVLLGSARYSTPVDIWSIGTIFAELAT--KKPLFH 205
++++ D+WS G + E+ + ++P ++
Sbjct: 214 ---------KFTSASDVWSFGVVMWEVMSYGERPYWN 297
>31789
Length = 676
Score = 41.6 bits (96), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 33/114 (28%), Positives = 56/114 (49%), Gaps = 6/114 (5%)
Frame = +2
Query: 9 KIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQD 68
+IG G++ VYKG G VA +++ + + E +LKEL+HPNIV D
Sbjct: 341 EIGRGSFKTVYKGLDTELGVAVAWCELQDKKWNKTERQRFKEEAEMLKELQHPNIVRFFD 520
Query: 69 VLMQDSR-----LYLIFEFL-SMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGI 116
+ + + L+ E + S LK YL ++ ++K++ QIL+G+
Sbjct: 521 YWEEHNHRNRKVIILVTELMTSGTLKTYLKRFKK---INLKVLKNWCRQILKGL 673
>37602
Length = 804
Score = 40.4 bits (93), Expect = 8e-04, Method: Compositional matrix adjust.
Identities = 16/37 (43%), Positives = 27/37 (72%)
Frame = -1
Query: 111 QILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADF 147
+ L+G+ + H R +HRD+K N+L+ ++G +KLADF
Sbjct: 195 ETLKGLHYLHRRGKMHRDIKGANILLTEEGDVKLADF 85
Score = 30.4 bits (67), Expect = 1.0, Method: Compositional matrix adjust.
Identities = 12/30 (40%), Positives = 19/30 (63%)
Frame = -2
Query: 1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVV 30
++D+ I+++G GTYG VYK + T G
Sbjct: 512 LDDFELIQRVGSGTYGDVYKAKA*TQGACC 423
>02638
Length = 1490
Score = 40.0 bits (92), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 31/123 (25%), Positives = 49/123 (39%)
Frame = +1
Query: 166 TLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNN 225
T+ + +PEVL G + Y D+WS+G + E+ T +P ++ + L IF+ + +
Sbjct: 25 TIAFMAPEVLRGES-YGRACDVWSVGCVMIEMCTCRPPWNSHDISNHLALIFKIASSVDP 201
Query: 226 EVWPEVESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHP 285
PE N+ DL+ + L D R S K L HP
Sbjct: 202 PPIPE------------------------NMSPPVRDLMLRCLEQDSDFRPSAKDLLMHP 309
Query: 286 YFN 288
F
Sbjct: 310 LFT 318
>20152
Length = 445
Score = 40.0 bits (92), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 31/120 (25%), Positives = 46/120 (38%)
Frame = +1
Query: 172 PEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEV 231
PE+LLG + + VD+WS+G I L + F ++ + L I
Sbjct: 1 PEILLGDSYDAPAVDVWSLGVILYMLVVGEAPFQEANDSETLTMIM-------------- 138
Query: 232 ESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLD 291
D + P ++ DL+ KML +P R S L HP+ ND D
Sbjct: 139 ----DCRYQIP-----------PHISHKCQDLIEKMLQREPVDRASLPHILAHPWLNDGD 273
>25019
Length = 730
Score = 40.0 bits (92), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 22/63 (34%), Positives = 35/63 (55%)
Frame = +3
Query: 132 QNLLIDDKGTIKLADFGLARAFGIPIRVYTHEAITLWYRSPEVLLGSARYSTPVDIWSIG 191
+N+L+D G +KL DFGL + RV T+ Y +PE+L + + VD WS+G
Sbjct: 261 ENVLLDKDGHVKLTDFGLCKEAITGTRVTHTFCGTIEYMAPEILTRTG-HGKAVDWWSLG 437
Query: 192 TIF 194
+ +
Sbjct: 438 SSY 446
>07836
Length = 1478
Score = 39.7 bits (91), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 40/139 (28%), Positives = 68/139 (48%), Gaps = 15/139 (10%)
Frame = -1
Query: 27 GQVVAMKKIRLESEEEGVPSTAIREISLLKE--LRHPNIVSLQDVLMQDS----RLYLIF 80
G+ VA+K I +EE ++ RE L + LRH NI+ ++ + +L+LI
Sbjct: 1478 GENVAVK-IFFTTEE----ASWFRETELYQTVLLRHENILGFIAADIKGTGSWTQLFLIT 1314
Query: 81 EFL-SMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCHSR--------RVLHRDLKP 131
++ + L YL S + +DSS + + + + G+ H + HRD+K
Sbjct: 1313 DYHENGSLHDYLLS----RVLDSSEMLALAHSAICGLAHLHIEIFGTRGKPAIAHRDIKS 1146
Query: 132 QNLLIDDKGTIKLADFGLA 150
+N+L+ GT +AD GLA
Sbjct: 1145 KNILVKKNGTCCIADLGLA 1089
>00638
Length = 1595
Score = 39.3 bits (90), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 13/33 (39%), Positives = 25/33 (75%)
Frame = +2
Query: 105 VKSYLYQILQGIVFCHSRRVLHRDLKPQNLLID 137
++ YLY++++ + FCHS ++HRD+KP L++
Sbjct: 422 IRFYLYELMKALDFCHSMGIMHRDVKPSPPLVN 520
>26009
Length = 886
Score = 38.1 bits (87), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 14/32 (43%), Positives = 25/32 (78%)
Frame = +3
Query: 105 VKSYLYQILQGIVFCHSRRVLHRDLKPQNLLI 136
KS + Q++ + F HS++++HRD+KP+N+LI
Sbjct: 717 AKSVMKQLVSALDFMHSKQLVHRDIKPENVLI 812
>12672
Length = 773
Score = 38.1 bits (87), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 28/96 (29%), Positives = 47/96 (48%), Gaps = 10/96 (10%)
Frame = +3
Query: 114 QGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEAITLWYRSPE 173
GI + + +HRD+K N+L+D + T K+ DF A P + E T+ ++
Sbjct: 24 SGIQYLNDNGHVHRDIKTANILLDSEYTAKVGDF--ATVVSAP----SGEGKTV--QNAS 179
Query: 174 VLLGSARY----------STPVDIWSIGTIFAELAT 199
V++G+A Y ST +D +S G + E+ T
Sbjct: 180 VVIGTAAYLAPEAIHFDVSTKLDSYSFGVVLLEVIT 287
>00394
Length = 548
Score = 37.7 bits (86), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 21/60 (35%), Positives = 31/60 (51%)
Frame = -2
Query: 9 KIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQD 68
+IG G++ VYKG G VA +++ + + E +LKEL+HPNIV D
Sbjct: 277 EIGRGSFKTVYKGLDTELGVAVAWCELQDKKWNKAERQRFKEEAEMLKELQHPNIVRFFD 98
>21800
Length = 855
Score = 37.4 bits (85), Expect = 0.007, Method: Compositional matrix adjust.
Identities = 36/119 (30%), Positives = 59/119 (49%), Gaps = 20/119 (16%)
Frame = +2
Query: 47 TAIREISLLKELRHPN--------IVSLQDVL----MQDSRLYLIFEFLSMDLKKYL--- 91
TA+ EI LLK +R+ + V L D + + + ++FE L +L K +
Sbjct: 431 TALDEIKLLKCVRNSDETDPAREKSVQLLDDFKISGVNGTHVCMVFEVLGYNLLKLIIRS 610
Query: 92 --DSIPPGQYMDSSLVKSYLYQILQGIVFCHSR-RVLHRDLKPQNLLI--DDKGTIKLA 145
IP VK + Q+L+G+ + H++ ++H D+KP+N+LI DD KLA
Sbjct: 611 NYQGIPVHN------VKLIIRQVLEGLNYLHAKCNIIHTDIKPENILICVDDNYIRKLA 769
>15549
Length = 470
Score = 36.2 bits (82), Expect = 0.015, Method: Compositional matrix adjust.
Identities = 14/39 (35%), Positives = 28/39 (71%)
Frame = -1
Query: 2 EDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESE 40
+++ IE++G+G YG+V++ ++K Q A+K+I L S+
Sbjct: 218 DEFECIEQMGKGGYGIVFRAKNKVDEQEYAVKRIALPSD 102
>20773
Length = 391
Score = 34.3 bits (77), Expect = 0.056, Method: Compositional matrix adjust.
Identities = 11/35 (31%), Positives = 25/35 (71%)
Frame = -1
Query: 252 HVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPY 286
H + ++ +L+ ++L YDP++R++ +AL+HP+
Sbjct: 334 HTTVVTQHFYNLVQRLLTYDPSQRLTPDLALSHPF 230
>17644
Length = 463
Score = 33.9 bits (76), Expect = 0.087, Method: Compositional matrix adjust.
Identities = 11/35 (31%), Positives = 24/35 (68%)
Frame = +3
Query: 252 HVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPY 286
H + ++ BL+ ++L YDP++R++ +AL+HP+
Sbjct: 57 HTTVVTQHFYBLVQRLLTYDPSQRLTPDLALSHPF 161
>18481
Length = 437
Score = 32.7 bits (73), Expect = 0.17, Method: Compositional matrix adjust.
Identities = 16/46 (34%), Positives = 26/46 (56%), Gaps = 3/46 (6%)
Frame = -1
Query: 111 QILQGIVFCHSRRVLHRDLKPQNLLID---DKGTIKLADFGLARAF 153
Q+L + F H + +HRDLKP N L+ + + DFGL++ +
Sbjct: 173 QLLSRLEFIHQKCFIHRDLKPDNFLMGLGRHCHRLYIIDFGLSKRY 36
>32357
Length = 625
Score = 32.7 bits (73), Expect = 0.17, Method: Compositional matrix adjust.
Identities = 14/30 (46%), Positives = 22/30 (73%)
Frame = -2
Query: 4 YTKIEKIGEGTYGVVYKGRHKTTGQVVAMK 33
Y ++KIG G++G +Y G H T+G+ VA+K
Sbjct: 432 YRLMKKIGSGSFGEIYLGVHNTSGEEVAVK 343
>38560
Length = 479
Score = 32.7 bits (73), Expect = 0.21, Method: Compositional matrix adjust.
Identities = 31/121 (25%), Positives = 48/121 (39%), Gaps = 1/121 (0%)
Frame = -3
Query: 169 YRSPEVLLGSARYSTPVDIWSIGT-IFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEV 227
Y +PE++ G + DIWS+G ++A L P D + L
Sbjct: 387 YAAPELISGLEYLGSEADIWSMGVLLYALLCGYLPF--DDEKXSHL-------------- 256
Query: 228 WPEVESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYF 287
+ Q K+ P+W L E+ LL ML DP+ RI+ + L+H +
Sbjct: 255 ---*QKNQKRKDEVPEW-----------LSEDTTKLLEGMLQTDPSHRITIRRLLDHHWL 118
Query: 288 N 288
N
Sbjct: 117 N 115
>35032
Length = 465
Score = 32.0 bits (71), Expect = 0.30, Method: Compositional matrix adjust.
Identities = 12/27 (44%), Positives = 19/27 (70%)
Frame = +3
Query: 261 LDLLSKMLIYDPAKRISGKMALNHPYF 287
DL+ ++L YDP+KR++ AL HP+
Sbjct: 144 FDLVKRLLNYDPSKRLTPXXALAHPFL 224
>15931
Length = 447
Score = 31.6 bits (70), Expect = 0.41, Method: Compositional matrix adjust.
Identities = 13/30 (43%), Positives = 19/30 (63%)
Frame = +1
Query: 261 LDLLSKMLIYDPAKRISGKMALNHPYFNDL 290
DL+ KML Y+ + R S + A+ HP+F L
Sbjct: 76 FDLMDKMLSYEVSTRYSLRQAMRHPFFRKL 165
>20513
Length = 405
Score = 30.0 bits (66), Expect = 1.3, Method: Compositional matrix adjust.
Identities = 10/25 (40%), Positives = 16/25 (64%)
Frame = -1
Query: 262 DLLSKMLIYDPAKRISGKMALNHPY 286
D L+ ML +DP +R + +L HP+
Sbjct: 282 DFLAPMLEFDPEQRATAAQSLQHPW 208
>29360
Length = 363
Score = 29.3 bits (64), Expect = 1.9, Method: Compositional matrix adjust.
Identities = 29/121 (23%), Positives = 54/121 (44%), Gaps = 8/121 (6%)
Frame = +3
Query: 24 KTTGQVVAMKKIRLESEEEGVPSTAIR---EISLLKELRHP-----NIVSLQDVLMQDSR 75
K T ++VA+K ++ PS A + E+S+L+ L N V + +
Sbjct: 18 KGTSEIVAIKILK------NHPSYARQGQIEVSILQRLSQESADDYNFVRAFECFQHKNH 179
Query: 76 LYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCHSRRVLHRDLKPQNLL 135
L+FE L +L +L Q + ++ Q+L + ++H DLKP+N++
Sbjct: 180 TCLVFEMLEQNLYDFLKQ-NKFQPLPLKYIRPITQQVLTALRKLKQLGLIHADLKPENIM 356
Query: 136 I 136
+
Sbjct: 357 L 359
>01007
Length = 897
Score = 28.9 bits (63), Expect = 3.0, Method: Compositional matrix adjust.
Identities = 16/46 (34%), Positives = 26/46 (56%)
Frame = -1
Query: 78 LIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCHSRR 123
LI + + L+ L S+ GQ ++S+ VK Y+ GI+F H +R
Sbjct: 369 LICHCIFIALRNRLLSLLTGQILESA-VKCYVMLFYVGIIFSHGKR 235
>21210
Length = 518
Score = 28.5 bits (62), Expect = 3.1, Method: Compositional matrix adjust.
Identities = 19/57 (33%), Positives = 27/57 (47%), Gaps = 4/57 (7%)
Frame = +3
Query: 169 YRSPEVL---LGSARYSTPVDIWSIGTIFAELATKK-PLFHGDSEIDQLFRIFRALG 221
Y +PE + S Y D+WS+G ELAT + P S DQL ++ R +
Sbjct: 18 YMAPERIDPRASSHGYDVRSDVWSLGITLMELATGRFPYRKWVSIFDQLQQVVRGVA 188
>17516
Length = 453
Score = 27.7 bits (60), Expect = 5.7, Method: Compositional matrix adjust.
Identities = 12/29 (41%), Positives = 17/29 (58%)
Frame = -3
Query: 169 YRSPEVLLGSARYSTPVDIWSIGTIFAEL 197
Y +PEVLL +Y D++S+ I EL
Sbjct: 421 YMAPEVLLQKGQYDMKADVYSLAIILWEL 335
>13305
Length = 549
Score = 27.7 bits (60), Expect = 5.7, Method: Compositional matrix adjust.
Identities = 11/38 (28%), Positives = 19/38 (50%)
Frame = +2
Query: 181 YSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFR 218
Y+T D+WS G + E+ T + ++ QLF +
Sbjct: 56 YTTQSDVWSFGVVLWEIFTLGGTPYSSTDTQQLFAFLK 169
>17806
Length = 433
Score = 27.3 bits (59), Expect = 8.4, Method: Compositional matrix adjust.
Identities = 28/102 (27%), Positives = 50/102 (49%), Gaps = 8/102 (7%)
Frame = +1
Query: 7 IEKIGEGTYGVVYK--GRHKTTGQ-----VVAMKKIRLESEEEGVPSTAIREISLLKELR 59
++++G G +G V + TTG VV M K +E+ + E++ +EL
Sbjct: 64 LKELGTGWFGKVIESDAERITTGVSRSKVVVKMLKDDATKDEQLL---FFEEVAPFRELD 234
Query: 60 HPNIVSLQDVLMQDSRLYLIFEFLSM-DLKKYLDSIPPGQYM 100
HPNIV L + + + ++ E ++ +LK+YL + Q M
Sbjct: 235 HPNIVRLLGQCTEMNPMLMLMECAALGNLKQYLRNHRHQQAM 360
>26052
Length = 562
Score = 26.9 bits (58), Expect = 8.8, Method: Compositional matrix adjust.
Identities = 11/27 (40%), Positives = 19/27 (70%)
Frame = -1
Query: 10 IGEGTYGVVYKGRHKTTGQVVAMKKIR 36
+G G++G V +HK TG+ +A+K I+
Sbjct: 367 LGVGSFGKVMALQHKDTGETLAVKNIQ 287
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000371400 | hsapiens_gene_ensembl | Casein kinase
II subunit alpha (EC 2.7.11.1) (CK II).
[Source:Uniprot/SWISSPROT;Acc:P68400]
(395 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
03508 401 e-112
00638 145 6e-47
12704 125 2e-29
01060 106 2e-23
14126 103 1e-22
01707 97 1e-20
04591 91 1e-18
04138 87 1e-17
32000 86 4e-17
29581 85 4e-17
01756 77 2e-14
21079 77 2e-14
15910 70 1e-12
26560 69 4e-12
23319 69 4e-12
00300 62 3e-10
12721 62 5e-10
12786 61 6e-10
13212 61 7e-10
01392 60 1e-09
30755 60 1e-09
28638 60 1e-09
01966 60 2e-09
14420 58 8e-09
18921 57 1e-08
27405 57 1e-08
26711 55 4e-08
03294 55 4e-08
31885 55 4e-08
19761 55 4e-08
18484 55 6e-08
09606 54 8e-08
18287 54 9e-08
19094 54 1e-07
13592 54 1e-07
18401 50 1e-06
03240 50 2e-06
21433 49 3e-06
13078 48 6e-06
31489 47 9e-06
13066 47 2e-05
04852 46 2e-05
07940 46 3e-05
11185 45 6e-05
00715 44 9e-05
17975 42 4e-04
14116 41 9e-04
37602 41 0.001
01718 40 0.001
01106 39 0.003
26009 39 0.004
06358 39 0.005
05084 39 0.005
00392 39 0.005
21800 37 0.014
32359 28 0.024
27546 36 0.029
02638 35 0.044
28157 35 0.066
18481 35 0.073
29360 34 0.11
15931 33 0.16
19301 33 0.19
26909 33 0.21
29590 33 0.24
11801 33 0.28
14104 33 0.28
12672 31 0.85
27274 31 1.0
35032 30 1.4
37063 30 1.6
17932 30 1.9
16350 30 2.0
20513 29 3.3
18663 29 3.7
20773 28 5.4
28419 28 6.8
20152 28 7.4
>03508
Length = 1463
Score = 401 bits (1031), Expect = e-112, Method: Compositional matrix adjust.
Identities = 187/233 (80%), Positives = 201/233 (86%)
Frame = +1
Query: 1 MSGPVPSRARVYTDVNTHRPREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINIT 60
+S P+PSRARVY DVNTH+ REYWDYESHVVEWGNQDDYQ+VRKLGRGKYSEVFEAIN+T
Sbjct: 481 VSMPLPSRARVYADVNTHKAREYWDYESHVVEWGNQDDYQIVRKLGRGKYSEVFEAINVT 660
Query: 61 NNEXXXXXXXXXXXXXXXXXXXXXLENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTD 120
NNE LENLRGG N+ITL IVKDPVSRTPAL+FEHVNNTD
Sbjct: 661 NNEKCVIKILKPVKKKKIKREIKILENLRGGTNVITLLAIVKDPVSRTPALIFEHVNNTD 840
Query: 121 FKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAE 180
FKQLYQT TDYDIRFY+YE++KALD+CHSMGIMHRDVKPHNVMIDHE++KLRLIDWGLAE
Sbjct: 841 FKQLYQTFTDYDIRFYLYELMKALDFCHSMGIMHRDVKPHNVMIDHENKKLRLIDWGLAE 1020
Query: 181 FYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFF 233
FYHPG EYNVRVASRYFKGPELL+DYQMYDYSLDMWSLGCM ASMIFRKEP
Sbjct: 1021FYHPGMEYNVRVASRYFKGPELLLDYQMYDYSLDMWSLGCMFASMIFRKEPLL 1179
Score = 186 bits (471), Expect = 2e-47, Method: Compositional matrix adjust.
Identities = 89/115 (77%), Positives = 97/115 (84%), Gaps = 3/115 (2%)
Frame = +2
Query: 216 WSLGCMLASM---IFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDI 272
W+ G A + K PFFHGHDNYDQLVRIAKVLGT+DLY YI+KY I+LDPRFNDI
Sbjct: 1118 WTCGVWAACLPA*SSGKSPFFHGHDNYDQLVRIAKVLGTDDLYGYIEKYQIDLDPRFNDI 1297
Query: 273 LGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTV 327
LGRHSRKRWERFVHSENQHL+SPEALDFLDKLLRYDH RLTAREAM+HPYF +
Sbjct: 1298 LGRHSRKRWERFVHSENQHLISPEALDFLDKLLRYDHNERLTAREAMDHPYFXPI 1462
>00638
Length = 1595
Score = 145 bits (365), Expect(2) = 6e-47, Method: Compositional matrix adjust.
Identities = 65/75 (86%), Positives = 71/75 (94%)
Frame = +2
Query: 85 LENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKAL 144
LENLRGG N+ITL IVKDPVSRTPAL+FEHVNNTDFKQLYQT TDYDIRFY+YE++KAL
Sbjct: 278 LENLRGGTNVITLLAIVKDPVSRTPALIFEHVNNTDFKQLYQTFTDYDIRFYLYELMKAL 457
Query: 145 DYCHSMGIMHRDVKP 159
D+CHSMGIMHRDVKP
Sbjct: 458 DFCHSMGIMHRDVKP 502
Score = 60.8 bits (146), Expect(2) = 6e-47, Method: Compositional matrix adjust.
Identities = 27/29 (93%), Positives = 29/29 (100%)
Frame = +1
Query: 35 NQDDYQLVRKLGRGKYSEVFEAINITNNE 63
NQDDYQ+VRKLGRGKYSEVFEAIN+TNNE
Sbjct: 127 NQDDYQIVRKLGRGKYSEVFEAINVTNNE 213
>12704
Length = 641
Score = 125 bits (315), Expect = 2e-29, Method: Compositional matrix adjust.
Identities = 56/63 (88%), Positives = 61/63 (96%)
Frame = +3
Query: 1 MSGPVPSRARVYTDVNTHRPREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINIT 60
++ P+PSRARVY DVNTH+PREYWDYESHVVEWGNQDDYQ+VRKLGRGKYSEVFEAINIT
Sbjct: 423 ITMPLPSRARVYADVNTHKPREYWDYESHVVEWGNQDDYQIVRKLGRGKYSEVFEAINIT 602
Query: 61 NNE 63
NNE
Sbjct: 603 NNE 611
>01060
Length = 1800
Score = 106 bits (264), Expect = 2e-23, Method: Compositional matrix adjust.
Identities = 66/242 (27%), Positives = 123/242 (50%), Gaps = 7/242 (2%)
Frame = +1
Query: 93 NIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQ------TLTDYDIRFYMYEILKALDY 146
NI+ L D++ + LVFE ++ D K L ++ Y+++I+ + +
Sbjct: 253 NIVCLEDVIME--DERLFLVFEFLS-MDLKMYIDKFPEGVVLDRRLVKSYVFQIVTGIXF 423
Query: 147 CHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAE-FYHPGQEYNVRVASRYFKGPELLVD 205
CH I+HRD+KP N++I+H +++ D+G+A F P + Y V + +++ PE+L+
Sbjct: 424 CHQRRIVHRDLKPQNLLINHTG-AIKIADFGMARTFALPVRAYTHEVVTLWYRAPEILMG 600
Query: 206 YQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIEL 265
Y +D+WS+G + A M+ R P F G DQL +I +++GT + + + +
Sbjct: 601 ASKYSTPVDVWSIGTIFADMLIRT-PIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKL-- 771
Query: 266 DPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFY 325
P FN + W+ SE + LD +++ L+ D R++ ++ ++H YF
Sbjct: 772 -PAFNGMF-----PLWKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYFL 933
Query: 326 TV 327
V
Sbjct: 934 NV 939
>14126
Length = 1265
Score = 103 bits (257), Expect = 1e-22, Method: Compositional matrix adjust.
Identities = 69/243 (28%), Positives = 122/243 (50%), Gaps = 10/243 (4%)
Frame = +3
Query: 92 PNIITLADIVKDPVSRTPA---LVFEHVNNTDFKQLYQT----LTDYDIRFYMYEILKAL 144
PN++ L D+ + ++ LVFE++ + L + L I+ M ++L +
Sbjct: 378 PNVVRLLDVSHNTITDREIRLNLVFEYIEHDLATYLAKCPSPGLGPDRIKDLMLQLLNGV 557
Query: 145 DYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLV 204
D+ HS I+HRD+KP N++I + R L+L D+GLA Y V + +++ PE+L+
Sbjct: 558 DFLHSNRIVHRDLKPQNLLISKDGR-LKLADFGLARIYSFHMALTTVVVTLWYRSPEVLM 734
Query: 205 DYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIE 264
+ Y S+D+WS GC+ A + F + F G +DQL +I +V+G D+ + ++
Sbjct: 735 QAE-YGTSVDIWSCGCIFAEL-FTRRALFKGSSEFDQLKKIFEVIGLPPAGDWPEGVSVH 908
Query: 265 LDPRFNDILGRHSRKRWERFVHSENQHLV---SPEALDFLDKLLRYDHQSRLTAREAMEH 321
R + Q LV P+A D ++K+L + R+++RE++ H
Sbjct: 909 -------------RNSFRPTPPVPLQTLVPEMDPQAKDLMEKMLVFKSGRRISSRESLLH 1049
Query: 322 PYF 324
PY
Sbjct: 1050PYL 1058
>01707
Length = 757
Score = 96.7 bits (239), Expect = 1e-20, Method: Compositional matrix adjust.
Identities = 63/223 (28%), Positives = 114/223 (51%), Gaps = 9/223 (4%)
Frame = +1
Query: 37 DDYQLVRKLGRGKYSEVFEAINITNNEXXXXXXXXXXX-----XXXXXXXXXXLENLRGG 91
+ Y+ + K+G G Y VF+ N ++ L+ L+
Sbjct: 64 EKYEKIGKIGEGSYGVVFKCRNKETSQLVAIKKFVESEDDPLIKKIAMREIRMLKQLKH- 240
Query: 92 PNIITLADIVKDPVSRTPALVFEHVNNTDFKQL---YQTLTDYDIRFYMYEILKALDYCH 148
PN++ L ++ + + LVF++V++T +L + L + ++ +Y+ L A+++CH
Sbjct: 241 PNLVRLIEVFRR--KKRLHLVFDYVDHTLLNELDRYPRGLPEPMVKRIIYQTLLAVNFCH 414
Query: 149 SMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYH-PGQEYNVRVASRYFKGPELLVDYQ 207
+HRDVKP N++I + +++L D+G A PG EY VA+R+++ PELLV
Sbjct: 415 QYNTIHRDVKPENILITRQG-QVKLCDFGFARILTGPGDEYTDYVATRWYRAPELLVGDT 591
Query: 208 MYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLG 250
Y +D+W++GC+ A ++ + + G + DQL I K LG
Sbjct: 592 QYGPPVDVWAIGCVFAELL-TGQALWPGRSDVDQLHLIRKTLG 717
>04591
Length = 1117
Score = 90.5 bits (223), Expect = 1e-18, Method: Compositional matrix adjust.
Identities = 68/244 (27%), Positives = 117/244 (47%), Gaps = 10/244 (4%)
Frame = -2
Query: 93 NIITLADIV---KDPVSR---TPALVFEHVNNTDFKQLYQTL----TDYDIRFYMYEILK 142
N++ L +I P +R T L+FE+ + D L L + D + M ++L
Sbjct: 1038 NVVQLQEICHTQAGPYNRYKSTFYLIFEYCD-YDLAGLLNNLRVKFSLADKKNLMSQLLN 862
Query: 143 ALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPEL 202
L Y H+ I+HRD+K N+++ + L+L D+GL+ + + RV + +++ PEL
Sbjct: 861 GLFYIHTKQILHRDIKAANILLTRDG-VLKLADFGLSRPWVKSKRLTNRVVTLWYRPPEL 685
Query: 203 LVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYN 262
L+ + Y +DMW +GC++A M RK P G QL I + G+ + +
Sbjct: 684 LLGEREYGPEIDMWGVGCIMAEMWSRK-PLMQGRSEQHQLSLITDLCGSLNAEVWPGVTK 508
Query: 263 IELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHP 322
+EL + + G+ RK ER + L + E + +D LR D R+ A+ H
Sbjct: 507 LELYGKLDLPQGK-PRKVKERML----DLLKNKEGAELIDIFLRLDPGQRMNCDNALSHD 343
Query: 323 YFYT 326
+F+
Sbjct: 342 FFWV 331
>04138
Length = 800
Score = 86.7 bits (213), Expect = 1e-17, Method: Compositional matrix adjust.
Identities = 56/195 (28%), Positives = 101/195 (51%), Gaps = 6/195 (3%)
Frame = +1
Query: 144 LDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPG----QEYNVRVASRYFKG 199
L Y H I+HRD+K N++I + L+L D+GLA + Y RV + +++
Sbjct: 52 LYYIHRNKILHRDMKAANILITKQG-VLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRP 228
Query: 200 PELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLG--TEDLYDY 257
PELL+ + Y ++D W GC++A M + + P G +QL I ++ G T +++
Sbjct: 229 PELLLGDRNYSTAIDQWGAGCIMAEM-WTRNPIMQGTTEQNQLTLITQLCGSITPEVWPG 405
Query: 258 IDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTARE 317
+ + ++ + GR + R +RF + L P LD ++LL+ D R++A E
Sbjct: 406 VTQLSMYHQIKGALAAGRKNIIR-DRFA----RILKDPYGLDLFERLLKMDPSQRISADE 570
Query: 318 AMEHPYFYTVVKDQA 332
A+ H +F+ V+ ++
Sbjct: 571 ALNHDFFWVGVEPKS 615
>32000
Length = 644
Score = 85.5 bits (210), Expect = 4e-17, Method: Compositional matrix adjust.
Identities = 52/158 (32%), Positives = 81/158 (51%), Gaps = 3/158 (1%)
Frame = -1
Query: 170 KLRLIDWGLAE-FYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFR 228
K+++ D+GLA F P + Y V + +++ PE+L+ + Y +D+WSLGC+ M+ R
Sbjct: 575 KMKIADFGLARVFGLPVRTYTHEVITLWYRAPEILLGCRFYSVPVDIWSLGCIFVEMMTR 396
Query: 229 KEPFFHGHDNYDQLVRIAKVLGTED--LYDYIDKYNIELDPRFNDILGRHSRKRWERFVH 286
+ F G DQL RI + LGT D ++ + K P + + K E V
Sbjct: 395 RA-LFPGDSEIDQLYRIFRTLGTPDEKVWPGVSKL-----PDYKPTFPKWPLKNLETVVS 234
Query: 287 SENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYF 324
+S LD L ++L Y+ R++AR AM HPYF
Sbjct: 233 ------LSKVGLDLLKRMLTYNPNRRISARSAMRHPYF 138
>29581
Length = 1278
Score = 85.1 bits (209), Expect = 4e-17, Method: Compositional matrix adjust.
Identities = 67/253 (26%), Positives = 122/253 (48%), Gaps = 13/253 (5%)
Frame = -2
Query: 85 LENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTL----TDYDIRFYMYEI 140
L NLR NI+ L ++V + LV E+ D L + ++ ++ + ++
Sbjct: 1193 LLNLRHQ-NIVQLQEVVVGKSLDSLFLVMEYCEQ-DLASLLDNMPAPFSESQVKCIVLQL 1020
Query: 141 LKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFY-HPGQEYNVRVASRYFKG 199
LK L Y H I+HRD+K N+++ + +++ D+GLA Y P + +V + +++
Sbjct: 1019 LKGLRYLHEAFIIHRDLKVSNLLMT-DKGCVKIADFGLARNYGKPQKPMTPKVVTLWYRA 843
Query: 200 PELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTED------ 253
PELL + + ++DMWS GC+L ++ K P G + Q+ I ++LGT +
Sbjct: 842 PELLFGSKTHSTAIDMWSAGCILGELLGHK-PLMPGRSDLQQIELIMELLGTPNDTIWPG 666
Query: 254 --LYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQS 311
+++ ++ P +N++ RH+ W +S + L+ L Y Q
Sbjct: 665 FSQLPAFEQFTLKKQP-YNNL--RHTFP-W-----------LSESGIRLLNGLFMYHPQK 531
Query: 312 RLTAREAMEHPYF 324
R TA + +EH YF
Sbjct: 530 RATAEDCLEHSYF 492
>01756
Length = 1858
Score = 76.6 bits (187), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 66/269 (24%), Positives = 114/269 (42%), Gaps = 19/269 (7%)
Frame = -3
Query: 2 SGPVPSRARVYTDVNTHRPREYWDYESHVVEWGNQD-DYQLVRKLGRGKYSEVFEAINIT 60
S SR R D + P YE+ + ++D Y+ + K+G+G + EVF+A
Sbjct: 1835 STASASREREQKDSQRYSP-----YETLKFPFCDEDAKYEKLAKIGQGTFGEVFKARCKK 1671
Query: 61 NNEXXXXXXXXXXXXXXXXXXXXXLE----NLRGGPNIITLADIVKDPVSRTPA------ 110
+ E L N++ L +I +
Sbjct: 1670 TKQVVAMKKVLMDNEKEGFPITALREIKILQLLNHENVVDLIEICSTKATSANRYKSMFY 1491
Query: 111 LVFEHVNNTDFKQLYQTLTDY----DIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDH 166
LVFE + D L ++ +I+ M +++ L Y H I+HRD+K N++I
Sbjct: 1490 LVFEFCEH-DLAGLLSNMSVVFNLPEIKEVMKQLMNGLYYIHRNKILHRDMKAANILITK 1314
Query: 167 EHRKLRLIDWGLAEFYHPG----QEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCML 222
+ L+L D+GLA + Y RV + +++ PELL+ + Y ++D W GC++
Sbjct: 1313 QG-VLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRPPELLLGDRNYSTAIDQWGAGCIM 1137
Query: 223 ASMIFRKEPFFHGHDNYDQLVRIAKVLGT 251
A M + + P G +QL I ++ G+
Sbjct: 1136 AEM-WTRNPIMQGTTEQNQLTLITQLCGS 1053
>21079
Length = 878
Score = 76.6 bits (187), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 44/135 (32%), Positives = 75/135 (55%), Gaps = 5/135 (3%)
Frame = +1
Query: 92 PNIITLADIVKDPVSRTPALVFEHVNNTD-FKQLYQ---TLTDYDIRFYMYEILKALDYC 147
P ++ L D + P RT LV E V + F+++ + LT+ D ++ +I + Y
Sbjct: 4 PKLLMLWDAFEAP--RTMVLVMEFVGAGELFERVIRDDFVLTERDCVHFVRQICSGVGYM 177
Query: 148 HSMGIMHRDVKPHNVM-IDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDY 206
H+ I+H D+KP NV+ + ++++ID+GLA FY PG V + F PE +V+Y
Sbjct: 178 HTQSILHLDLKPENVLCVSDNSNQIKIIDFGLARFYKPGDSLQVLFGTPEFIAPE-VVNY 354
Query: 207 QMYDYSLDMWSLGCM 221
+++ DMWS+G +
Sbjct: 355 DEINFTTDMWSIGVI 399
>15910
Length = 1361
Score = 70.5 bits (171), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 54/201 (26%), Positives = 91/201 (45%), Gaps = 2/201 (0%)
Frame = +2
Query: 129 TDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMID--HEHRKLRLIDWGLAEFYHPGQ 186
T+ D + +IL + Y H+ G++HRD+KP N++ + + KL+L D+GL+ P
Sbjct: 458 TEKDAARAISDILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLADFGLSRIIEPEV 637
Query: 187 EYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIA 246
+ + + + PE+L + Y S+DMWS+G + ++ EPFF ++
Sbjct: 638 QMSTVCGTPGYCAPEVLKGDK-YTPSVDMWSVGVIAYILLCGYEPFFAENEF-------- 790
Query: 247 KVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLR 306
++Y I K + D + W +S A D + KLL
Sbjct: 791 ------EMYRKIIKGEYKFDEEY-----------WSE---------ISENAKDVVRKLLV 892
Query: 307 YDHQSRLTAREAMEHPYFYTV 327
D + RLTA EA+ P+ V
Sbjct: 893 IDPKKRLTATEALRLPWVKGV 955
>26560
Length = 398
Score = 68.9 bits (167), Expect = 4e-12, Method: Compositional matrix adjust.
Identities = 36/106 (33%), Positives = 63/106 (59%)
Frame = -1
Query: 127 TLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQ 186
T+ ++RFY E++ L++ HS +++RD+KP N+++D E+ +R+ D GLA + +
Sbjct: 368 VFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLD-ENGHVRISDLGLACDFSKKR 192
Query: 187 EYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPF 232
+ V + + PE+L+ Q YD S D +S GCML ++ PF
Sbjct: 191 PH-ASVGTHGYMAPEVLMKGQSYDSSADWFSFGCMLYKLLKGHSPF 57
>23319
Length = 2235
Score = 68.6 bits (166), Expect = 4e-12, Method: Compositional matrix adjust.
Identities = 42/120 (35%), Positives = 60/120 (50%), Gaps = 2/120 (1%)
Frame = +3
Query: 207 QMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLG--TEDLYDYIDKYNIE 264
+MY S+DMWS GC+ A + P F G+D+ DQL RI K+LG TED + + +
Sbjct: 21 KMYSTSIDMWSAGCIFAELANAGRPLFPGNDDDDQLKRIFKLLGTPTEDQWPGMTQL--- 191
Query: 265 LDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYF 324
P + H W++ V N + D L LL R++A EA++HPYF
Sbjct: 192 --PNYRMFPMYHVTTTWQQVVPKLNS-----KGRDLLQCLLVCCPSDRMSADEALQHPYF 350
>00300
Length = 2318
Score = 62.4 bits (150), Expect = 3e-10, Method: Compositional matrix adjust.
Identities = 53/226 (23%), Positives = 104/226 (46%), Gaps = 18/226 (7%)
Frame = -1
Query: 39 YQLVRKLGRGKYSEVFEAINITNNEXXXXXXXXXXXXXXXXXXXXXLENLRGGPNIITLA 98
+Q K+G G++ +V+ A+N++ E L+ LR + I +
Sbjct: 1652 WQRGNKIGEGQFGKVYTAVNMSTGELMALKEMKFQPND--------LQQLREMCDEIKIF 1497
Query: 99 DIVKDP---------VSRTPALVF-EHVNNTDFKQLYQT-LTDYDIRFYMYEILKALDYC 147
+ ++ V + L+F E+ + ++ + L +Y IR Y EI+ A+++
Sbjct: 1496 EGIQHENLVKYYGVEVHKDEMLMFMEYCDTGTIEEAAKMGLPEYLIRRYTREIVLAVNHL 1317
Query: 148 HSMGIMHRDVKPHNVMIDHEHRKLRLIDWGL-----AEFYHPGQEYNVRVASRYFKGPEL 202
H I+HRD+K N+ + + ++L D+G + PG+ +N+ V + + PE+
Sbjct: 1316 HENSIVHRDIKGANIFLT-SNGHVKLGDFGCSVKLKSHTTMPGEFHNL-VGTTAYMAPEV 1143
Query: 203 LV--DYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIA 246
D Y + D+WSLGC++ M K P+ +NY + ++
Sbjct: 1142 FTQNDQGGYGRAADIWSLGCVVIEMATGKRPWHDLDNNYQIMYKVG 1005
>12721
Length = 821
Score = 61.6 bits (148), Expect = 5e-10, Method: Compositional matrix adjust.
Identities = 33/95 (34%), Positives = 57/95 (60%), Gaps = 1/95 (1%)
Frame = +1
Query: 141 LKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGL-AEFYHPGQEYNVRVASRYFKG 199
LKAL + H+ G++HRD+K ++++ H+ K++L D+G A+ Q+ V + Y+
Sbjct: 403 LKALAFLHANGVIHRDIKSDSILLSHDG-KVKLXDFGFCAQVTQDLQKRKSLVGTPYWMA 579
Query: 200 PELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFH 234
PE++ Y +D+WSLG M+ MI + PFF+
Sbjct: 580 PEVISRLP-YGPEVDIWSLGIMVMEMIDAEPPFFN 681
>12786
Length = 460
Score = 61.2 bits (147), Expect = 6e-10, Method: Compositional matrix adjust.
Identities = 43/142 (30%), Positives = 72/142 (50%), Gaps = 22/142 (15%)
Frame = -3
Query: 126 QTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPG 185
Q L I+FY E+L+A+ H+ G++H D+KP N M+ + L+LID+G+A
Sbjct: 425 QGLDRMMIKFYWREMLRAVKALHNEGVIHSDLKPANFMLVAGN--LKLIDFGIANTLQQD 252
Query: 186 QEY---NVRVASRYFKGPELLV-------DYQMYD--------YSL----DMWSLGCMLA 223
+ + RV + + PE ++ D M + Y + D+WSLGC+L
Sbjct: 251 KTSVLKDSRVGTPSYMSPEAIMAACDDSADDSMEEDGHRTKPKYKVGVRSDVWSLGCILY 72
Query: 224 SMIFRKEPFFHGHDNYDQLVRI 245
+M++ + PF H +N +L I
Sbjct: 71 NMVYGRTPFQHIKNNMGKLQAI 6
>13212
Length = 1067
Score = 61.2 bits (147), Expect = 7e-10, Method: Compositional matrix adjust.
Identities = 53/208 (25%), Positives = 89/208 (42%), Gaps = 7/208 (3%)
Frame = -1
Query: 124 LYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVM--IDHEHRKLRLIDWGL-AE 180
L + +T+ I + +E+ ALD+ H ++HRD+K NV+ ID E ++L D+G+ A+
Sbjct: 1001 LEKPMTEAQICYVCHEMCMALDFLHRHHVIHRDIKAGNVLLTIDGE---VKLADFGVSAK 831
Query: 181 FYHPGQEYNVRVASRYFKGPELLVDYQM----YDYSLDMWSLGCMLASMIFRKEPFFHGH 236
Q+ + + + Y+ PE+++ + YD+ D+WSLG L + P H
Sbjct: 830 NTQTQQKRDTFIGTPYWMAPEVVLCETLKDTPYDFKADIWSLGVTLIEFAQIEPPNKEMH 651
Query: 237 DNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPE 296
L++I K +D K+W +
Sbjct: 650 -PMRVLIKIHK----------------------SDPPTLEKPKKWTKLFK---------- 570
Query: 297 ALDFLDKLLRYDHQSRLTAREAMEHPYF 324
DF+ K L D R TA E +EHP+
Sbjct: 569 --DFIAKCLVKDPNLRPTAAELLEHPFM 492
>01392
Length = 1806
Score = 60.5 bits (145), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 56/211 (26%), Positives = 88/211 (41%), Gaps = 12/211 (5%)
Frame = -1
Query: 128 LTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDH--EHRKLRLIDWGLAEFYH-- 183
L + + + I +ALD+ HS GI HRD+KP N++ +H + +++ D+ LA
Sbjct: 1800 LCEREASLVVRHIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGISCD 1621
Query: 184 ----PGQEYNVRVASRYFKGPEL----LVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHG 235
E V S + PE+ + D YD D+WSLG +L M+ PF
Sbjct: 1620 GDGTKTPELLTPVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILYIMLCGYPPF--- 1450
Query: 236 HDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSP 295
Y Q E +D D FN I H + S+ +S
Sbjct: 1449 ---YGQCGEDCGWNRGEACHDCQDML-------FNSIQDGHYK------FPSQEWTSISS 1318
Query: 296 EALDFLDKLLRYDHQSRLTAREAMEHPYFYT 326
A D + LL + + R +A + ++HP+ T
Sbjct: 1317 SAKDLIRHLLVREPRKRYSAADVLKHPWICT 1225
>30755
Length = 1137
Score = 60.1 bits (144), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 39/123 (31%), Positives = 65/123 (52%), Gaps = 2/123 (1%)
Frame = +2
Query: 128 LTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLA-EFYHPGQ 186
T+ RFY EI+ AL Y HS GI++RD+K N+++D + +++ D+GL E G+
Sbjct: 23 FTEERTRFYGAEIISALGYLHSQGIIYRDLKLENLLLDKDGH-IKVADFGLCKEDITYGR 199
Query: 187 EYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFH-GHDNYDQLVRI 245
+ + PE+L D Y ++D W G ++ MI + PF++ HD L+ +
Sbjct: 200 TTKTFCGTPEYLAPEVLDDND-YGRAVDWWGTGVVMYEMICGRLPFYNRDHDVLFTLILV 376
Query: 246 AKV 248
V
Sbjct: 377 EDV 385
>28638
Length = 1458
Score = 60.1 bits (144), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 28/77 (36%), Positives = 48/77 (62%), Gaps = 1/77 (1%)
Frame = -1
Query: 150 MGIMHRDVKPHNVMIDHEHRK-LRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQM 208
M I+H D+KP N+++ + R ++++D+G GQ + SR+++ PE+L+
Sbjct: 774 MNIIHCDLKPENILLCNPKRSAIKIVDFG--SSCQLGQRIYQYIQSRFYRSPEVLLGVP- 604
Query: 209 YDYSLDMWSLGCMLASM 225
YD ++DMWSLGC+L M
Sbjct: 603 YDLAIDMWSLGCILVEM 553
Score = 32.7 bits (73), Expect = 0.24, Method: Compositional matrix adjust.
Identities = 32/141 (22%), Positives = 60/141 (42%), Gaps = 32/141 (22%)
Frame = -2
Query: 216 WSLGCMLASMIFRK----EPFFHGHDNYDQLVRIAKVLG------------TEDLYDYI- 258
W L C ++ + + P F G + +DQ+++I +VLG T +D +
Sbjct: 596 WPLTCGXWAVYWWRCTXGNPLFAGSNEFDQMMKIVEVLGVPPRHILDQAQKTRKYFDLLP 417
Query: 259 ------------DKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLR 306
KY + +++LG R + E H V+ + L F D +LR
Sbjct: 416 DGTYAPKKPRDNKKYKSPSSRKLHEVLGAEKGGPGGRRM-GEPGHTVA-DYLKFKDLILR 243
Query: 307 ---YDHQSRLTAREAMEHPYF 324
+D ++R++ A++H +F
Sbjct: 242 MLDFDPKTRISPYYALQHNFF 180
>01966
Length = 1735
Score = 59.7 bits (143), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 37/136 (27%), Positives = 72/136 (52%), Gaps = 7/136 (5%)
Frame = -1
Query: 93 NIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQ------TLTDYDIRFYMYEILKALDY 146
NI+ L D++ + LVFE ++ D K L ++ Y+++I+ +++
Sbjct: 1531 NIVCLEDVIME--DERLFLVFEFLS-MDLKMYIDKFPEGVVLDRRLVKSYVFQIVTGINF 1361
Query: 147 CHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAE-FYHPGQEYNVRVASRYFKGPELLVD 205
CH I+HRD+KP N++I+H +++ D+G+A F P + Y V + +++ PE+L+
Sbjct: 1360 CHQRRIVHRDLKPQNLLINHTG-AIKIADFGMARTFALPVRAYTHEVVTLWYRAPEILMG 1184
Query: 206 YQMYDYSLDMWSLGCM 221
Q + W+ G +
Sbjct: 1183 PQ---STPPXWTCGAL 1145
Score = 57.0 bits (136), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 32/119 (26%), Positives = 58/119 (48%)
Frame = -3
Query: 209 YDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPR 268
Y +D+WS+G + A M+ R P F G DQL +I +++GT + + + + P
Sbjct: 1175 YSTPVDVWSIGTIFADMLIRT-PIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKL---PA 1008
Query: 269 FNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTV 327
FN + W+ SE + LD +++ L+ D R++ ++ ++H YF V
Sbjct: 1007 FNGMF-----PLWKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYFLNV 846
>14420
Length = 528
Score = 57.8 bits (138), Expect = 8e-09, Method: Compositional matrix adjust.
Identities = 30/97 (30%), Positives = 55/97 (56%), Gaps = 1/97 (1%)
Frame = +2
Query: 139 EILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQ-EYNVRVASRYF 197
E L+AL++ H ++HRD+K N+++ + ++L D+G P Q + + V + Y+
Sbjct: 221 ECLQALEFLHENQVIHRDIKSDNILLGMDG-SVKLTDFGFCAQLSPEQSKRSTMVGTPYW 397
Query: 198 KGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFH 234
PE++ Q Y ++D+WSLG M MI + P+ +
Sbjct: 398 MAPEVVTRKQ-YGPTVDIWSLGVMCIEMIEGEPPYLN 505
>18921
Length = 697
Score = 57.0 bits (136), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 34/110 (30%), Positives = 57/110 (51%), Gaps = 1/110 (0%)
Frame = +2
Query: 126 QTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLA-EFYHP 184
+TL + +I +Y LK L Y HS +HRD+K N+++++E +L D+G+A +
Sbjct: 302 KTLVEREIATILYYTLKGLXYLHSRRKIHRDIKAGNILLNNEGHA-KLADFGVAGQLTDT 478
Query: 185 GQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFH 234
+ N + + Y+ PE++ + YD D+WSLG M K P
Sbjct: 479 MAKRNTVIGTPYWMAPEVIQEIG-YDCVADIWSLGITALEMAEGKPPVME 625
>27405
Length = 532
Score = 57.0 bits (136), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 35/128 (27%), Positives = 67/128 (52%), Gaps = 3/128 (2%)
Frame = -3
Query: 90 GGPNIITLADIVKDPVSRTPALVFEHVNNTDFK---QLYQTLTDYDIRFYMYEILKALDY 146
G P I+ + + P + + +N D + T+ ++RFY E++ L++
Sbjct: 380 GSPFIVCMTYAFQTP--EKLCFILDLMNGGDLHYHLSQHGVFTEKEVRFYAAEVMLGLEH 207
Query: 147 CHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDY 206
HS +++RD+KP N+++D E+ +R+ D GLA + ++ + V + + PE+L+
Sbjct: 206 MHSRFVVYRDLKPANILLD-ENGHVRISDLGLACDFSK-KKPHASVGTHGYMAPEVLMKG 33
Query: 207 QMYDYSLD 214
Q YD S D
Sbjct: 32 QAYDSSAD 9
>26711
Length = 405
Score = 55.5 bits (132), Expect = 4e-08, Method: Compositional matrix adjust.
Identities = 28/95 (29%), Positives = 53/95 (55%), Gaps = 1/95 (1%)
Frame = -2
Query: 139 EILKALDYCHSMGIMHRDVKPHNVMIDHEH-RKLRLIDWGLAEFYHPGQEYNVRVASRYF 197
++L L + H+ G++H D+KP N+++ + ++LID+GLA +P QE + + F
Sbjct: 392 QVLDILQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARKLYPPQETFLNHGTPGF 213
Query: 198 KGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPF 232
PE L D + + D+W +G + ++ + PF
Sbjct: 212 TSPEAL-DVKPISTASDVWGVGVLAYILLSGQSPF 111
>03294
Length = 1684
Score = 55.5 bits (132), Expect = 4e-08, Method: Compositional matrix adjust.
Identities = 31/117 (26%), Positives = 58/117 (49%)
Frame = -1
Query: 211 YSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFN 270
+ +D+WS+G + A M+ R P F G DQL +I +++GT + + + + P FN
Sbjct: 1678 HPVDVWSIGTIFADMLIRT-PIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKL---PAFN 1511
Query: 271 DILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTV 327
+ W+ SE + LD +++ L+ D R++ ++ ++H YF V
Sbjct: 1510 GMF-----PLWKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYFLNV 1355
>31885
Length = 529
Score = 55.5 bits (132), Expect = 4e-08, Method: Compositional matrix adjust.
Identities = 29/104 (27%), Positives = 55/104 (52%), Gaps = 4/104 (3%)
Frame = -2
Query: 133 IRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRV 192
++FY+ ++ LDY S I+HRD+KP N+++D E + D+ +A +
Sbjct: 366 VKFYLCQLALVLDYLRSQKIVHRDIKPDNILLD-EQGHCHVTDFNIATQLEDDELATSTS 190
Query: 193 ASRYFKGPEL----LVDYQMYDYSLDMWSLGCMLASMIFRKEPF 232
+R + PE+ + + + Y + +D WSLG L ++ ++ PF
Sbjct: 189 GTRPYMAPEVYGVAINERRGYGFPVDWWSLGVSLFELLKKRRPF 58
>19761
Length = 473
Score = 55.5 bits (132), Expect = 4e-08, Method: Compositional matrix adjust.
Identities = 38/125 (30%), Positives = 62/125 (49%), Gaps = 3/125 (2%)
Frame = -3
Query: 133 IRFYMYEILKALDYCHSMG--IMHRDVKPHNVMIDHEHRKLRLIDWGLA-EFYHPGQEYN 189
I ++ + AL+Y H+ I+HRD+KP N+ + E +RL D GLA + P
Sbjct: 417 IVCWLMQTASALNYMHTHTPVILHRDLKPQNIYVT-EKGDVRLGDLGLARKLTGPADFAT 241
Query: 190 VRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVL 249
+V + + PE+L Q Y+ D+WSLGC+ + +K G D + + +V+
Sbjct: 240 SQVGTIMYLSPEIL-SQQPYNSKSDIWSLGCVFYDITGKK-----GSDEMGVMFLLVQVM 79
Query: 250 GTEDL 254
G L
Sbjct: 78 GGRKL 64
>18484
Length = 635
Score = 54.7 bits (130), Expect = 6e-08, Method: Compositional matrix adjust.
Identities = 35/104 (33%), Positives = 55/104 (52%), Gaps = 6/104 (5%)
Frame = +1
Query: 135 FYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVAS 194
FY EI L + H GI++RD+K NVM+D E +++ D+G+ + G +
Sbjct: 55 FYAAEIAVGLFFLHDQGIIYRDLKLDNVMLDSEGH-IKIADFGMCKEGMTGD-----ATT 216
Query: 195 RYFKG------PELLVDYQMYDYSLDMWSLGCMLASMIFRKEPF 232
R F G PE+++ YQ Y S+D W+ G +L M+ + PF
Sbjct: 217 RTFCGTPDYIAPEIVL-YQPYSKSVDWWAYGVLLFEMLAGQPPF 345
>09606
Length = 1300
Score = 54.3 bits (129), Expect = 8e-08, Method: Compositional matrix adjust.
Identities = 54/222 (24%), Positives = 91/222 (40%), Gaps = 25/222 (11%)
Frame = -3
Query: 128 LTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAE------- 180
L + IR + ++ L Y HS+GI+ D++P V++D L+ D+GL++
Sbjct: 842 LPETSIRDFGIHLVTGLHYIHSLGILFHDLRPSKVLLD-TSGVLKFADFGLSKVEGENLE 666
Query: 181 -----FYHPGQEYNVRVASRYFK-----------GPELLVDYQMYDYSL--DMWSLGCML 222
F G ++N++ A K PE+ +Q + S+ D+W+LGC+
Sbjct: 665 ELFFKFAEAGDQWNIQSAEEMMKQVPTSGSPTYMAPEV---FQGAEPSIMSDLWALGCVF 495
Query: 223 ASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWE 282
M F P F G + YD + KVL E + + P
Sbjct: 494 YEM-FSGHPPFLG-ETYD--ITKDKVLNKEFPLPKVKGSRLSAKP--------------- 372
Query: 283 RFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYF 324
SPE L+ L+ LL+ D RL+ ++H ++
Sbjct: 371 -----------SPEFLNLLESLLQKDSTRRLSWASLVKHAFW 279
>18287
Length = 678
Score = 54.3 bits (129), Expect = 9e-08, Method: Compositional matrix adjust.
Identities = 35/119 (29%), Positives = 63/119 (52%), Gaps = 3/119 (2%)
Frame = -3
Query: 209 YDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGT---EDLYDYIDKYNIEL 265
YDYS+D+WS+GC+ A ++ R+ F QL I ++GT ED+ +
Sbjct: 673 YDYSIDIWSVGCIFAELLSRRI-LFQAQGPVQQLDMIINLVGTPRPEDMERACEGAR--- 506
Query: 266 DPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYF 324
N IL + R++ +++ + H + EA+ L ++L + ++R++A EA+ HPY
Sbjct: 505 ----NHILNQPFRRQNLLTLYNLSPH-ATHEAVRLLTRMLILNPKNRISAEEALSHPYL 344
>19094
Length = 898
Score = 53.9 bits (128), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 32/101 (31%), Positives = 55/101 (54%), Gaps = 1/101 (0%)
Frame = +1
Query: 126 QTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLA-EFYHP 184
+TL + +I +Y LK L Y HS +HRD+K N+++++E +L D+G+A +
Sbjct: 43 KTLVEREIATILYYTLKGL*YLHSRRKIHRDIKAGNILLNNEGHA-KLADFGVAGQLTDT 219
Query: 185 GQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASM 225
+ N + + Y+ PE++ + YD D+WSLG M
Sbjct: 220 MAKRNTVIGTPYWMAPEVIQEIG-YDCVADIWSLGITALEM 339
>13592
Length = 980
Score = 53.5 bits (127), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 63/296 (21%), Positives = 114/296 (38%), Gaps = 16/296 (5%)
Frame = +2
Query: 44 KLGRGKYSEVFEAINITNNEXXXXXXXXXX--XXXXXXXXXXXLENLRGGPNIITLADIV 101
K+G+G++ +V+ A+N E L+ L G I ++V
Sbjct: 5 KIGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETRALKNVAEELKILEG----IKHKNLV 172
Query: 102 K---DPVSRTPALVFEHVNNT----DFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMH 154
+ V R L+F + + +L L + R + ++L + H GI+H
Sbjct: 173 RYYGIEVHREELLIFMELCSEGTLESLVELTGGLPEALSRRFTAQLLSGVAELHKHGIVH 352
Query: 155 RDVKPHNVMIDHEHRKLRLIDWGLAEFYH-----PGQEYNVRVASRYFKGPELLVDYQMY 209
RD+K N+ + L+L D+G A PG E V ++ + PE+
Sbjct: 353 RDIKTANIFLVDGSNSLKLGDFGSAVKIQAHTTVPG-ELQGYVGTQAYMAPEVFTKTNSD 529
Query: 210 DYS--LDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDP 267
+ D+WS+GC++ M K P+ N+ + ++ +G + P
Sbjct: 530 GHGRLADIWSVGCVVVEMASGKRPWAQFDSNFQIMFKVG--MGEK--------------P 661
Query: 268 RFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPY 323
+ + L S E DF+D L++D + RL+A E +E +
Sbjct: 662 QAPESL--------------------SQEGHDFIDHCLQHDPKQRLSAIELLEQNF 769
>18401
Length = 463
Score = 50.4 bits (119), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 35/143 (24%), Positives = 75/143 (52%), Gaps = 10/143 (6%)
Frame = -3
Query: 192 VASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGT 251
V++R+++ PE++++ + + D+WS+GC++ ++ F HDN + L + ++LG+
Sbjct: 449 VSTRHYRAPEVILELG-WSHPCDVWSVGCIMFE-LYTGYTLFQTHDNKEHLAMMERILGS 276
Query: 252 EDLYDYIDK-------YNIELDPRFNDILGRHSRKRWE---RFVHSENQHLVSPEALDFL 301
Y K ++ LD + R+ R+ + R+V + ++ + D +
Sbjct: 275 LP-YRMAKKTKKQKYFHHGRLDVPERSSMARYVRENTKPLLRYV-KDRENKDHQQLFDLM 102
Query: 302 DKLLRYDHQSRLTAREAMEHPYF 324
KLL Y+ SR + +A++HP+F
Sbjct: 101 KKLLAYEASSRYSLLQALQHPFF 33
>03240
Length = 1683
Score = 49.7 bits (117), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 36/145 (24%), Positives = 57/145 (39%), Gaps = 45/145 (31%)
Frame = -3
Query: 134 RFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGL--------------- 178
RFY+ E+++A++ H MG +HRD+KP N++ID ++L D+GL
Sbjct: 982 RFYVAELVQAIESVHRMGFIHRDIKPDNILIDRNGH-IKLTDFGLCTGFRWTHNSKYYQR 806
Query: 179 ---------------------AEFYHPGQEYNVR---------VASRYFKGPELLVDYQM 208
E P + R V + + PE+L
Sbjct: 805 DGTHARQDSMEVKCQLDEQCQCEILKPLERRRKREQRCLAHSLVGTPNYIAPEVLSRLGG 626
Query: 209 YDYSLDMWSLGCMLASMIFRKEPFF 233
Y D WS+G +L M+ PF+
Sbjct: 625 YTSVCDWWSVGVILFEMLVGHPPFY 551
>21433
Length = 590
Score = 48.9 bits (115), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 43/172 (25%), Positives = 76/172 (44%)
Frame = +2
Query: 136 YMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASR 195
Y+Y++ AL+YCH ++HRD+KP N+++ L++ D+G + + P +
Sbjct: 182 YIYQLSSALEYCHYRKVIHRDIKPENLLLG-LKGDLKIADFGWS-VHAPSSRRTTMCGTL 355
Query: 196 YFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLY 255
+ PE +V+ + +D ++D+WSLG + Y+ LV GT L
Sbjct: 356 DYLPPE-MVEGKTHDENVDLWSLGVLC----------------YEFLV------GTPPLR 466
Query: 256 DYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRY 307
+ PR+ S + +V+P A D + KLLR+
Sbjct: 467 PSPTRPPTPASPRWT----------------SGSPSIVTPGARDLISKLLRH 574
>13078
Length = 773
Score = 48.1 bits (113), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 37/126 (29%), Positives = 61/126 (48%), Gaps = 14/126 (11%)
Frame = -1
Query: 213 LDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDK-------YNIEL 265
D+WS+GC++ ++ F HDN + L + ++LG+ Y K Y+ L
Sbjct: 734 CDVWSIGCIMFE-LYTGYTLFQTHDNKEHLAMMERILGSLP-YRMAKKTKKQKYFYHGRL 561
Query: 266 DPRFNDILGRHSR---KRWERFV----HSENQHLVSPEALDFLDKLLRYDHQSRLTAREA 318
D GR+ R K R+V + ++Q L D +DK+L Y+ +R + R+A
Sbjct: 560 DWDEKSSAGRYVRDNVKPLRRYVKDPDNEDHQQL-----FDLMDKMLSYEVSTRYSLRQA 396
Query: 319 MEHPYF 324
M HP+F
Sbjct: 395 MRHPFF 378
>31489
Length = 329
Score = 47.4 bits (111), Expect = 9e-06, Method: Compositional matrix adjust.
Identities = 27/77 (35%), Positives = 49/77 (63%), Gaps = 6/77 (7%)
Frame = +3
Query: 93 NIITLADIVKDPVS----RTPALVFEHVNNTDFKQLY--QTLTDYDIRFYMYEILKALDY 146
NII++ +I+K S + +VF+ + + + +Y Q LT+ IR+++Y+IL+ L Y
Sbjct: 33 NIISIREILKPKDSYHDFKDIHVVFDLMESDLHRIIYSDQPLTEEHIRYFLYQILRGLKY 212
Query: 147 CHSMGIMHRDVKPHNVM 163
HS ++HRD+KP N++
Sbjct: 213 IHSANVVHRDLKPSNLL 263
>13066
Length = 551
Score = 46.6 bits (109), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 27/90 (30%), Positives = 45/90 (50%), Gaps = 4/90 (4%)
Frame = +3
Query: 134 RFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGL--AEFYHPGQEYNVR 191
+ + Y++ AL+Y HS + HRD+K N+++ H ++L D+G A G++Y R
Sbjct: 285 KIWFYQMTTALNYLHSYDVAHRDLKCENILLS-SHFNVKLADFGFACACITESGEKYMSR 461
Query: 192 --VASRYFKGPELLVDYQMYDYSLDMWSLG 219
S + PE++ D WSLG
Sbjct: 462 TYCGSAAYAAPEIVYGAPYAPKVADAWSLG 551
>04852
Length = 1462
Score = 46.2 bits (108), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 28/90 (31%), Positives = 46/90 (51%), Gaps = 3/90 (3%)
Frame = +1
Query: 136 YMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASR 195
Y ++I + +++ S +HRD+ NV++ EH L++ D+GL+ G Y R R
Sbjct: 340 YAFQIARGMEFLASRKCIHRDLAARNVLVTEEH-VLKIADFGLS---RTGDYYKKRSGGR 507
Query: 196 Y---FKGPELLVDYQMYDYSLDMWSLGCML 222
+ PE L D + Y D+WS G +L
Sbjct: 508 LPVKWMAPEALFDMR-YTTKSDVWSFGVVL 594
>07940
Length = 1336
Score = 45.8 bits (107), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 29/105 (27%), Positives = 56/105 (53%), Gaps = 4/105 (3%)
Frame = -3
Query: 122 KQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLA-- 179
+ + + LT D+ Y Y++ + ++Y S +HRD+ NV++ E+ L++ D+GL
Sbjct: 374 QDMLKMLTPKDLISYAYQVARGMEYLASKQCIHRDLAARNVLVAEEY-VLKIADFGLTRN 198
Query: 180 --EFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCML 222
+F + + + R+ ++ PE L D + Y D+WS G +L
Sbjct: 197 LQQFDYYRKTTDGRLPVKWM-APEALFDRK-YTSKSDVWSYGVLL 69
>11185
Length = 473
Score = 44.7 bits (104), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 31/120 (25%), Positives = 55/120 (45%), Gaps = 25/120 (20%)
Frame = +1
Query: 132 DIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAE----------- 180
IR + ++ L Y HS+GI+ D++P V++D L+ D+GL++
Sbjct: 4 SIRDFGIHLVTGLHYIHSLGILFHDLRPSKVLLD-TSGVLKFADFGLSKVEGENLEELFF 180
Query: 181 -FYHPGQEYNVRVASRYFK-----------GPELLVDYQMYDYSL--DMWSLGCMLASMI 226
F G ++N++ A K PE+ +Q + S+ D+W+LGC+ M
Sbjct: 181 KFAEAGDQWNIQSAEEMMKQVPTSGSPTYMAPEV---FQGAEPSIMSDLWALGCVFYEMF 351
>00715
Length = 1788
Score = 44.3 bits (103), Expect = 9e-05, Method: Compositional matrix adjust.
Identities = 38/149 (25%), Positives = 63/149 (42%), Gaps = 27/149 (18%)
Frame = +1
Query: 111 LVFEHVNNTDFKQL---YQTLTDYDIRFYM-YEILKALDYCHSMGIMHRDVKPHNVMIDH 166
L E+V + + + +Q D +R + ++ + L Y HS+ I+H D+KP N ++
Sbjct: 166 LAMEYVGPLNLQTILNDHQQDIDSSMRLSLALQMARGLHYLHSINIVHLDLKPANCLLTR 345
Query: 167 EHRKLRLIDWGLAEFYHP-----------------------GQEYNVRVASRYFKGPELL 203
+ KLR+ D+G P G N + ++ PELL
Sbjct: 346 D-LKLRIADFGCCHQLTPTGLDMGEREGGMAGNELELTPVQGAWKNELAGTLAYRAPELL 522
Query: 204 VDYQMYDYSLDMWSLGCMLASMIFRKEPF 232
Q S D++SLG L M R+ P+
Sbjct: 523 KGLQPSVRS-DVYSLGITLWQMCTRQGPY 606
>17975
Length = 449
Score = 42.0 bits (97), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 16/44 (36%), Positives = 30/44 (68%)
Frame = +3
Query: 136 YMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLA 179
Y +I++A+ YCH + ++HRD+KP NV+ + ++L D+G +
Sbjct: 282 YFRQIVEAISYCHKLHVVHRDLKPENVVFFEKPGLVKLTDFGFS 413
>14116
Length = 1017
Score = 40.8 bits (94), Expect = 9e-04, Method: Compositional matrix adjust.
Identities = 27/105 (25%), Positives = 51/105 (48%), Gaps = 5/105 (4%)
Frame = -1
Query: 129 TDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLA-----EFYH 183
T D+ Y +I + +DY + +HRD+ N M+D E +++ D+GLA + Y+
Sbjct: 327 TIKDLIMYGVDIARGMDYLAGLKFVHRDLAARNCMLD-EDFHVKVADFGLARDIYEKEYY 151
Query: 184 PGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFR 228
+ ++ ++ L + YD D+WS G +L ++ R
Sbjct: 150 SSENKKAKLPVKWMALESL--EKGNYDSKTDVWSYGVVLWELLTR 22
>37602
Length = 804
Score = 40.8 bits (94), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 26/90 (28%), Positives = 40/90 (44%), Gaps = 3/90 (3%)
Frame = -1
Query: 111 LVFEHVNNTDFKQLYQT---LTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHE 167
+ E+ + +Y LT+ I F E LK L Y H G MHRD+K N+++ E
Sbjct: 288 IAMEYCGGGSMQDIYHVTGPLTEPQIAFVCRETLKGLHYLHRRGKMHRDIKGANILLTEE 109
Query: 168 HRKLRLIDWGLAEFYHPGQEYNVRVASRYF 197
D LA+F+ ++ V + F
Sbjct: 108 G------DVKLADFWRVSSNHSHNVQKKVF 37
>01718
Length = 959
Score = 40.0 bits (92), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 49/218 (22%), Positives = 90/218 (41%), Gaps = 9/218 (4%)
Frame = +3
Query: 20 PREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEXXXXXXXXXXXXXXXX 79
P+ H V + D + K+G G +SEVF+ + +
Sbjct: 96 PKSSCQALRHAVSALTRLDDFICEKIGAGFFSEVFKVTHRITGQVMALKMNTMTSNRHNM 275
Query: 80 XXXXXLENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTD---YDIRFY 136
L N NI+ + + AL E++ + + +QL + + + R
Sbjct: 276 LREVQLLNRLQHANILRFMGVCVHE-GQLHALT-EYIPSGNLEQLLEKKDEELPWTQRIQ 449
Query: 137 M-YEILKALDYCHSMGIMHRDVKPHNVMI---DHEHRKLRLIDWGLA-EFYHP-GQEYNV 190
+ + + LDY HS +HRD+ N++I D+ + D+GLA + P +E
Sbjct: 450 LTLGLARGLDYLHSTRFIHRDLTSKNILIRREDNHGYHAVIADFGLATKIPDPLDKEKLP 629
Query: 191 RVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFR 228
V S Y+ PE+L + Y+ D++S+G ++ + R
Sbjct: 630 TVGSPYWMAPEVL-NGHFYNERADLFSVGIIMCEITAR 740
>01106
Length = 878
Score = 39.3 bits (90), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 38/163 (23%), Positives = 68/163 (41%), Gaps = 18/163 (11%)
Frame = +3
Query: 20 PREYWDYESHVVEWGN--QDDYQLVRKLGRGKYSEV----------FEAINITNNEXXXX 67
PR+Y H V+ G+ Y ++RKLG G +S V F A+ + +
Sbjct: 261 PRDYCKGGYHPVKNGDLFNGRYHVIRKLGWGHFSTVWLCWDLTCKRFVALKVVKSAQHYT 440
Query: 68 XXXXXXXXXXXXXXXXXLENLRGGPNIITLADIVKDPVSRT-PALVFEHVNNTDFKQL-- 124
+ + + L D V+ T A+VFE + K +
Sbjct: 441 ETALDEVKLLKCVRESDVADPARAKCVQLLDDFKISGVNGTHVAMVFEVLGYNLLKLIIR 620
Query: 125 --YQTLTDYDIRFYMYEILKALDYCHSMG-IMHRDVKPHNVMI 164
YQ + ++++ + ++L+ L Y H+ I+H D+KP N++I
Sbjct: 621 SNYQGIPIHNVKLIIRQVLEGLSYMHAKCRIIHTDIKPENILI 749
>26009
Length = 886
Score = 38.9 bits (89), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 14/33 (42%), Positives = 24/33 (72%)
Frame = +3
Query: 132 DIRFYMYEILKALDYCHSMGIMHRDVKPHNVMI 164
+ + M +++ ALD+ HS ++HRD+KP NV+I
Sbjct: 714 EAKSVMKQLVSALDFMHSKQLVHRDIKPENVLI 812
>06358
Length = 1517
Score = 38.5 bits (88), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 48/176 (27%), Positives = 84/176 (47%), Gaps = 31/176 (17%)
Frame = +3
Query: 123 QLYQTLTDYDIRFYMYEILKALDYCHS-MGIMHRDVKPHNVMIDHEHRKLRLIDWGLA-- 179
Q YQ L D +I+ + ++ +AL + H+ +MHR+V P +M+ +L W LA
Sbjct: 339 QDYQ-LYDVEIKHGLLQVTEALGFLHNDAKMMHRNVCPEAIMLT------KLGSWKLAGY 497
Query: 180 EFY------------HPGQEYNVRVASRY-----FKGPELLVDYQMYDYSLDMWSLGCML 222
EF +P E+ +A F PE ++ Q S DM+SLG ++
Sbjct: 498 EFCVRSSDPQSTDPSYPFYEWRSDIAPVTQPHLDFMAPEYVLTMQCGTGS-DMFSLGLLV 674
Query: 223 ASMIFRKEPFFHGH-------DNYDQL--VRIAKVLGT--EDLYDYIDKYNIELDP 267
S+ + +P F + N ++L +R++ +LG EDL D++ K + ++P
Sbjct: 675 YSVFAKGKPLFECNGELSAFKSNAEELRHMRVS-LLGVVPEDLRDHV-KLLLNIEP 836
>05084
Length = 1324
Score = 38.5 bits (88), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 26/92 (28%), Positives = 40/92 (43%), Gaps = 2/92 (2%)
Frame = +2
Query: 235 GHDNYDQLVRIAKVLGTEDLYDYIDKYNI-ELDPRFNDI-LGRHSRKRWERFVHSENQHL 292
G DQLV I KVLGT + I E++P +++ + W +
Sbjct: 8 GDSGVDQLVEIIKVLGTP------TREQIREMNPNYSEFKFPQIKAHPWTKVFRPRT--- 160
Query: 293 VSPEALDFLDKLLRYDHQSRLTAREAMEHPYF 324
PEA+ + +LL Y +R+ EA H +F
Sbjct: 161 -PPEAIQLVSRLLEYTPSARIQPMEACAHAFF 253
>00392
Length = 668
Score = 38.5 bits (88), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 25/93 (26%), Positives = 51/93 (54%), Gaps = 3/93 (3%)
Frame = +3
Query: 133 IRFYMYEILKALDYCHSMG--IMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNV 190
++ + ++LK L + H+ ++HRD+K N+ I +++ D GLA + +V
Sbjct: 252 LKNWCRQVLKGLYFLHTRTPPVIHRDLKCDNIFITGPTGSVKIGDLGLATLKNQSFAKSV 431
Query: 191 RVASRYFKGPELLVDYQMYDYSLDMWSLG-CML 222
+ + F PE+ ++ YD ++D+++ G CML
Sbjct: 432 -IGTPEFMAPEMYEEH--YDEAVDVYAFGMCML 521
>21800
Length = 855
Score = 37.0 bits (84), Expect = 0.014, Method: Compositional matrix adjust.
Identities = 20/67 (29%), Positives = 38/67 (56%), Gaps = 6/67 (8%)
Frame = +2
Query: 125 YQTLTDYDIRFYMYEILKALDYCHS-MGIMHRDVKPHNVMI---DHEHRKLRL--IDWGL 178
YQ + ++++ + ++L+ L+Y H+ I+H D+KP N++I D+ RKL + +W
Sbjct: 614 YQGIPVHNVKLIIRQVLEGLNYLHAKCNIIHTDIKPENILICVDDNYIRKLAVDAFEWQR 793
Query: 179 AEFYHPG 185
PG
Sbjct: 794 LGLKLPG 814
>32359
Length = 928
Score = 28.5 bits (62), Expect(2) = 0.024, Method: Compositional matrix adjust.
Identities = 9/17 (52%), Positives = 14/17 (82%)
Frame = -3
Query: 151 GIMHRDVKPHNVMIDHE 167
G+ HRD+KP N+++D E
Sbjct: 65 GVCHRDIKPQNLLLDPE 15
Score = 26.6 bits (57), Expect(2) = 0.024, Method: Compositional matrix adjust.
Identities = 15/49 (30%), Positives = 26/49 (53%), Gaps = 6/49 (12%)
Frame = -1
Query: 111 LVFEHVNNTDFK------QLYQTLTDYDIRFYMYEILKALDYCHSMGIM 153
LV E+V T ++ + QT+ I+ YMY++ ++L Y HS +
Sbjct: 202 LVLEYVPETVYRVARHYSKSKQTIPILYIKLYMYQLFRSLAYIHSQACV 56
>27546
Length = 426
Score = 35.8 bits (81), Expect = 0.029, Method: Compositional matrix adjust.
Identities = 24/101 (23%), Positives = 47/101 (46%), Gaps = 11/101 (10%)
Frame = -1
Query: 92 PNIITLADIVKDPVSRTPAL-----------VFEHVNNTDFKQLYQTLTDYDIRFYMYEI 140
PNII + I++ R P + + H+ T + + + + +++
Sbjct: 300 PNIIQIHSILQ----RGPKIFIFMRYAEKGDMLSHIKKTG------PIDEAQTKVWFFQM 151
Query: 141 LKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEF 181
KAL Y HS I HRD+K N+++ + +++ D+G A +
Sbjct: 150 AKALQYLHSHDIAHRDLKCENILLS-KRLNVKIADFGFARY 31
>02638
Length = 1490
Score = 35.4 bits (80), Expect = 0.044, Method: Compositional matrix adjust.
Identities = 31/128 (24%), Positives = 52/128 (40%)
Frame = +1
Query: 197 FKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYD 256
F PE+L + Y + D+WS+GC++ M + P ++ HD + L I K+ +
Sbjct: 34 FMAPEVL-RGESYGRACDVWSVGCVMIEMCTCRPP-WNSHDISNHLALIFKIASS----- 192
Query: 257 YIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAR 316
+D I EN +SP D + + L D R +A+
Sbjct: 193 -VDPPPI-----------------------PEN---MSPPVRDLMLRCLEQDSDFRPSAK 291
Query: 317 EAMEHPYF 324
+ + HP F
Sbjct: 292 DLLMHPLF 315
>28157
Length = 400
Score = 34.7 bits (78), Expect = 0.066, Method: Compositional matrix adjust.
Identities = 29/105 (27%), Positives = 46/105 (43%), Gaps = 13/105 (12%)
Frame = +3
Query: 92 PNIITLADIVKD-PVSRTPALVFEHVNNTDFKQLYQTL---------TDYDIRFYMYEIL 141
PNI+ L +D PV LV E+ LY L T ++ +
Sbjct: 90 PNIVCLYGACRDHPV----CLVMEYAEGGS---LYNVLHGSGPQPQYTAAHAMNWLLQCA 248
Query: 142 KALDYCHSM---GIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYH 183
++Y H M ++HRD+KP N+++ KL++ D+G A H
Sbjct: 249 LGVEYLHGMKPKALIHRDLKPPNLLLIQCGTKLKICDFGTACDIH 383
>18481
Length = 437
Score = 34.7 bits (78), Expect = 0.073, Method: Compositional matrix adjust.
Identities = 19/51 (37%), Positives = 31/51 (60%), Gaps = 3/51 (5%)
Frame = -1
Query: 139 EILKALDYCHSMGIMHRDVKPHNVMID---HEHRKLRLIDWGLAEFYHPGQ 186
++L L++ H +HRD+KP N ++ H HR L +ID+GL++ Y Q
Sbjct: 173 QLLSRLEFIHQKCFIHRDLKPDNFLMGLGRHCHR-LYIIDFGLSKRYKDTQ 24
>29360
Length = 363
Score = 33.9 bits (76), Expect = 0.11, Method: Composition-based stats.
Identities = 21/66 (31%), Positives = 33/66 (50%), Gaps = 14/66 (21%)
Frame = +3
Query: 113 FEHVNNT--DFKQLYQTLTDY------------DIRFYMYEILKALDYCHSMGIMHRDVK 158
F+H N+T F+ L Q L D+ IR ++L AL +G++H D+K
Sbjct: 162 FQHKNHTCLVFEMLEQNLYDFLKQNKFQPLPLKYIRPITQQVLTALRKLKQLGLIHADLK 341
Query: 159 PHNVMI 164
P N+M+
Sbjct: 342 PENIML 359
>15931
Length = 447
Score = 33.5 bits (75), Expect = 0.16, Method: Compositional matrix adjust.
Identities = 12/29 (41%), Positives = 20/29 (68%)
Frame = +1
Query: 296 EALDFLDKLLRYDHQSRLTAREAMEHPYF 324
+ D +DK+L Y+ +R + R+AM HP+F
Sbjct: 70 QLFDLMDKMLSYEVSTRYSLRQAMRHPFF 156
>19301
Length = 712
Score = 33.1 bits (74), Expect = 0.19, Method: Compositional matrix adjust.
Identities = 27/105 (25%), Positives = 53/105 (50%), Gaps = 10/105 (9%)
Frame = +2
Query: 85 LENLR--GGPNIITLADIVKDPVSRTPA--LVFEHVNNTDFKQLYQTLTDYD------IR 134
+ NLR PNII+ + ++ P ++ E+ + QLY+ L D +
Sbjct: 422 IRNLRKLNHPNIISFKGVC----TQAPCYCIIMEYC---PYGQLYEVLRDGKEIPPALVL 580
Query: 135 FYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLA 179
+ +I ++Y HS I+HRD+K NV++ ++ +++ D+G +
Sbjct: 581 DWSKQIASGMNYLHSHKIIHRDLKSPNVLV-AKNDVVKISDFGTS 712
>26909
Length = 394
Score = 33.1 bits (74), Expect = 0.21, Method: Compositional matrix adjust.
Identities = 29/109 (26%), Positives = 43/109 (39%), Gaps = 10/109 (9%)
Frame = +2
Query: 226 IFRKEPFFHGHD---------NYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRH 276
+ EP FH ++DQL RI V+G D+ D + + R
Sbjct: 14 LLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFPQEKDWEDIRRMPEHQQLTKDFKRS 193
Query: 277 SRKRWERFVHSENQHL-VSPEALDFLDKLLRYDHQSRLTAREAMEHPYF 324
S + E + +A L KLL D R+T+ +AM+ PYF
Sbjct: 194 SYVNCNLMKYMEKHKVKADSKAFHLLQKLLTMDPVKRITSEQAMKDPYF 340
>29590
Length = 320
Score = 32.7 bits (73), Expect = 0.24, Method: Composition-based stats.
Identities = 18/58 (31%), Positives = 28/58 (48%)
Frame = +3
Query: 175 DWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPF 232
D G A + G++ + + + PE+L DY+ DMWSLG + M+ PF
Sbjct: 6 DLGFACLTNTGEDIRDIIGTPDYVAPEVL-DYEPLSIQTDMWSLGVLSYVMLTACSPF 176
>11801
Length = 743
Score = 32.7 bits (73), Expect = 0.28, Method: Compositional matrix adjust.
Identities = 26/93 (27%), Positives = 49/93 (52%), Gaps = 3/93 (3%)
Frame = -1
Query: 215 MWSLGCMLASMIFRKEPFFHGHDNYDQLVR---IAKVLGTEDLYDYIDKYNIELDPRFND 271
++S G L +++ +K P YDQL R +AKV+ + D++ I+LDP+++
Sbjct: 302 VFSGGTALRTLL-KKFPVTSSSIPYDQLQRRCSVAKVVSETSCCKFGDQF-IKLDPQYDY 129
Query: 272 ILGRHSRKRWERFVHSENQHLVSPEALDFLDKL 304
+ ++S + R+ QH+ +AL F D +
Sbjct: 128 RVAKYSYLQSYRYFDDHKQHIR--QALMFNDTI 36
>14104
Length = 573
Score = 32.7 bits (73), Expect = 0.28, Method: Compositional matrix adjust.
Identities = 11/32 (34%), Positives = 19/32 (59%)
Frame = +1
Query: 293 VSPEALDFLDKLLRYDHQSRLTAREAMEHPYF 324
+P+A+ F+ L+ D RLT + ++HPY
Sbjct: 88 AAPQAMSFMQSCLKMDPAERLTCHQLLQHPYM 183
>12672
Length = 773
Score = 31.2 bits (69), Expect = 0.85, Method: Compositional matrix adjust.
Identities = 23/92 (25%), Positives = 43/92 (46%), Gaps = 7/92 (7%)
Frame = +3
Query: 142 KALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPG-----QEYNVRVASRY 196
+ Y + G +HRD+K N+++D E+ ++ D+ G Q +V + +
Sbjct: 24 SGIQYLNDNGHVHRDIKTANILLDSEYTA-KVGDFATVVSAPSGEGKTVQNASVVIGTAA 200
Query: 197 FKGPELLVDYQMYDYS--LDMWSLGCMLASMI 226
+ PE + +D S LD +S G +L +I
Sbjct: 201 YLAPEAI----HFDVSTKLDSYSFGVVLLEVI 284
>27274
Length = 396
Score = 30.8 bits (68), Expect = 1.0, Method: Compositional matrix adjust.
Identities = 30/126 (23%), Positives = 50/126 (39%)
Frame = -1
Query: 199 GPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYI 258
G ELL Q + ++DMWSLG +L ++ PF Q+ R +
Sbjct: 381 GAELLRG-QQHGPTVDMWSLGILLHELLSGHVPF-EPERGSRQMARNMMAV--------- 235
Query: 259 DKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREA 318
+ I+ SR + +S DFL +L++ + RLT+++A
Sbjct: 234 ----------YAQIIRGSSRDVCDGLA-------LSTHGADFLRRLVQLEDTKRLTSQQA 106
Query: 319 MEHPYF 324
HP+
Sbjct: 105 FSHPWI 88
>35032
Length = 465
Score = 30.4 bits (67), Expect = 1.4, Method: Compositional matrix adjust.
Identities = 12/27 (44%), Positives = 16/27 (59%)
Frame = +3
Query: 299 DFLDKLLRYDHQSRLTAREAMEHPYFY 325
D + +LL YD RLT A+ HP+ Y
Sbjct: 147 DLVKRLLNYDPSKRLTPXXALAHPFLY 227
>37063
Length = 455
Score = 30.0 bits (66), Expect = 1.6, Method: Compositional matrix adjust.
Identities = 25/79 (31%), Positives = 37/79 (46%), Gaps = 13/79 (16%)
Frame = -2
Query: 157 VKPHNVMIDH--EHRKLRLIDWGLAEFYH------PGQEYNVRVASRYFKGPELLVDYQM 208
+KP N++ +H E L++ D+ LA + E V S + PE+ VD +
Sbjct: 454 LKPENILCEHLDEVVPLKICDFDLASGINCDGDGTKTPELLTPVGSAEYMAPEV-VDAWV 278
Query: 209 -----YDYSLDMWSLGCML 222
YD DMWSLG +L
Sbjct: 277 GESFSYDKRCDMWSLGIIL 221
>17932
Length = 597
Score = 30.0 bits (66), Expect = 1.9, Method: Compositional matrix adjust.
Identities = 17/35 (48%), Positives = 22/35 (62%)
Frame = -3
Query: 293 VSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTV 327
VS EA D + +LL D +SRL E +HP+F TV
Sbjct: 460 VSKEARDLISQLLS-DGKSRLGWPELQQHPFFKTV 359
>16350
Length = 1108
Score = 29.6 bits (65), Expect = 2.0, Method: Compositional matrix adjust.
Identities = 10/26 (38%), Positives = 18/26 (69%)
Frame = +3
Query: 299 DFLDKLLRYDHQSRLTAREAMEHPYF 324
DFL +L +D + R TA ++++HP+
Sbjct: 762 DFLAPMLEFDPEQRATAAQSLQHPWL 839
>20513
Length = 405
Score = 28.9 bits (63), Expect = 3.3, Method: Compositional matrix adjust.
Identities = 10/26 (38%), Positives = 18/26 (69%)
Frame = -1
Query: 299 DFLDKLLRYDHQSRLTAREAMEHPYF 324
DFL +L +D + R TA ++++HP+
Sbjct: 282 DFLAPMLEFDPEQRATAAQSLQHPWL 205
>18663
Length = 600
Score = 28.9 bits (63), Expect = 3.7, Method: Compositional matrix adjust.
Identities = 13/34 (38%), Positives = 21/34 (61%)
Frame = +2
Query: 199 GPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPF 232
PE+L + Y +S+D W+LG +L M+ + PF
Sbjct: 32 APEILRG-EDYGFSVDWWALGVLLYEMLAGRSPF 130
>20773
Length = 391
Score = 28.5 bits (62), Expect = 5.4, Method: Compositional matrix adjust.
Identities = 16/50 (32%), Positives = 25/50 (50%)
Frame = -1
Query: 274 GRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPY 323
G H R+ F H+ +V+ + + +LL YD RLT A+ HP+
Sbjct: 370 GLHRRRSRPVFPHTT---VVTQHFYNLVQRLLTYDPSQRLTPDLALSHPF 230
>28419
Length = 687
Score = 28.1 bits (61), Expect = 6.8, Method: Compositional matrix adjust.
Identities = 26/96 (27%), Positives = 43/96 (44%), Gaps = 5/96 (5%)
Frame = +3
Query: 140 ILKALDYCHSMG----IMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASR 195
ILK L YC ++ ++ K N+ EH K++ + G + +R S+
Sbjct: 342 ILKRLRYCLNLSKPPSYLNTVRKL*NISYVREHDKVKALMLGFKLLVNSQCANALRHPSQ 521
Query: 196 YFKGPELL-VDYQMYDYSLDMWSLGCMLASMIFRKE 230
KGPEL+ D+Q Y++ C+ + RKE
Sbjct: 522 I*KGPELIPYDFQFYEF-----PTACVTSPY*VRKE 614
>20152
Length = 445
Score = 27.7 bits (60), Expect = 7.4, Method: Compositional matrix adjust.
Identities = 12/39 (30%), Positives = 23/39 (58%)
Frame = +1
Query: 200 PELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDN 238
PE+L+ ++D+WSLG +L ++ + PF +D+
Sbjct: 1 PEILLGDSYDAPAVDVWSLGVILYMLVVGEAPFQEANDS 117
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000383086 | hsapiens_gene_ensembl | Casein kinase
II subunit alpha (EC 2.7.11.1) (CK II).
[Source:Uniprot/SWISSPROT;Acc:P68400]
(385 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
03508 400 e-112
00638 145 6e-47
12704 125 2e-29
01060 107 1e-23
14126 104 6e-23
01707 97 1e-20
04591 90 2e-18
04138 87 1e-17
32000 86 3e-17
29581 86 3e-17
21079 77 1e-14
01756 76 2e-14
15910 71 8e-13
26560 69 3e-12
23319 69 3e-12
12721 62 4e-10
00300 62 4e-10
12786 62 6e-10
13212 62 6e-10
01392 60 1e-09
28638 60 1e-09
30755 60 2e-09
01966 59 3e-09
14420 58 6e-09
27405 57 8e-09
18921 57 1e-08
26711 56 2e-08
03294 56 3e-08
19761 56 3e-08
31885 56 3e-08
18484 55 5e-08
09606 55 6e-08
18287 54 8e-08
19094 54 1e-07
13592 54 1e-07
18401 51 1e-06
03240 50 1e-06
21433 49 3e-06
13078 48 8e-06
31489 47 9e-06
13066 47 1e-05
04852 46 3e-05
07940 45 4e-05
11185 45 5e-05
00715 44 7e-05
17975 42 4e-04
37602 41 8e-04
01718 41 0.001
14116 40 0.001
01106 40 0.002
00392 39 0.003
26009 39 0.004
05084 39 0.005
06358 38 0.005
21800 37 0.013
32359 28 0.023
27546 36 0.026
02638 35 0.035
28157 35 0.045
18481 34 0.088
29360 33 0.16
15931 33 0.17
19301 33 0.17
29590 33 0.23
26909 33 0.24
14104 33 0.26
11801 32 0.41
12672 32 0.52
27274 31 0.76
35032 30 1.3
37063 30 1.5
16350 30 1.6
17932 30 2.2
20513 29 2.7
18663 29 3.8
20773 28 4.8
20152 28 5.6
28419 28 6.8
>03508
Length = 1463
Score = 400 bits (1027), Expect = e-112, Method: Compositional matrix adjust.
Identities = 187/233 (80%), Positives = 201/233 (86%)
Frame = +1
Query: 1 MSGPVPSRARVYTDVNTHRPREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINIT 60
+S P+PSRARVY DVNTH+ REYWDYESHVVEWGNQDDYQ+VRKLGRGKYSEVFEAIN+T
Sbjct: 481 VSMPLPSRARVYADVNTHKAREYWDYESHVVEWGNQDDYQIVRKLGRGKYSEVFEAINVT 660
Query: 61 NNEXXXXXXXXXXXXXXXXXXXXXLENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTD 120
NNE LENLRGG N+ITL IVKDPVSRTPAL+FEHVNNTD
Sbjct: 661 NNEKCVIKILKPVKKKKIKREIKILENLRGGTNVITLLAIVKDPVSRTPALIFEHVNNTD 840
Query: 121 FKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAE 180
FKQLYQT TDYDIRFY+YE++KALD+CHSMGIMHRDVKPHNVMIDHE++KLRLIDWGLAE
Sbjct: 841 FKQLYQTFTDYDIRFYLYELMKALDFCHSMGIMHRDVKPHNVMIDHENKKLRLIDWGLAE 1020
Query: 181 FYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFF 233
FYHPG EYNVRVASRYFKGPELL+DYQMYDYSLDMWSLGCM ASMIFRKEP
Sbjct: 1021FYHPGMEYNVRVASRYFKGPELLLDYQMYDYSLDMWSLGCMFASMIFRKEPLL 1179
Score = 186 bits (471), Expect = 2e-47, Method: Compositional matrix adjust.
Identities = 89/115 (77%), Positives = 97/115 (84%), Gaps = 3/115 (2%)
Frame = +2
Query: 216 WSLGCMLASM---IFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDI 272
W+ G A + K PFFHGHDNYDQLVRIAKVLGT+DLY YI+KY I+LDPRFNDI
Sbjct: 1118 WTCGVWAACLPA*SSGKSPFFHGHDNYDQLVRIAKVLGTDDLYGYIEKYQIDLDPRFNDI 1297
Query: 273 LGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTV 327
LGRHSRKRWERFVHSENQHL+SPEALDFLDKLLRYDH RLTAREAM+HPYF +
Sbjct: 1298 LGRHSRKRWERFVHSENQHLISPEALDFLDKLLRYDHNERLTAREAMDHPYFXPI 1462
>00638
Length = 1595
Score = 145 bits (365), Expect(2) = 6e-47, Method: Compositional matrix adjust.
Identities = 65/81 (80%), Positives = 74/81 (91%)
Frame = +2
Query: 85 LENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKAL 144
LENLRGG N+ITL IVKDPVSRTPAL+FEHVNNTDFKQLYQT TDYDIRFY+YE++KAL
Sbjct: 278 LENLRGGTNVITLLAIVKDPVSRTPALIFEHVNNTDFKQLYQTFTDYDIRFYLYELMKAL 457
Query: 145 DYCHSMGIMHRDVKPHNVMID 165
D+CHSMGIMHRDVKP +++
Sbjct: 458 DFCHSMGIMHRDVKPSPPLVN 520
Score = 60.8 bits (146), Expect(2) = 6e-47, Method: Compositional matrix adjust.
Identities = 27/29 (93%), Positives = 29/29 (100%)
Frame = +1
Query: 35 NQDDYQLVRKLGRGKYSEVFEAINITNNE 63
NQDDYQ+VRKLGRGKYSEVFEAIN+TNNE
Sbjct: 127 NQDDYQIVRKLGRGKYSEVFEAINVTNNE 213
>12704
Length = 641
Score = 125 bits (315), Expect = 2e-29, Method: Compositional matrix adjust.
Identities = 56/63 (88%), Positives = 61/63 (96%)
Frame = +3
Query: 1 MSGPVPSRARVYTDVNTHRPREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINIT 60
++ P+PSRARVY DVNTH+PREYWDYESHVVEWGNQDDYQ+VRKLGRGKYSEVFEAINIT
Sbjct: 423 ITMPLPSRARVYADVNTHKPREYWDYESHVVEWGNQDDYQIVRKLGRGKYSEVFEAINIT 602
Query: 61 NNE 63
NNE
Sbjct: 603 NNE 611
>01060
Length = 1800
Score = 107 bits (266), Expect = 1e-23, Method: Compositional matrix adjust.
Identities = 55/196 (28%), Positives = 106/196 (54%), Gaps = 1/196 (0%)
Frame = +1
Query: 133 IRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAE-FYHPGQEYNVR 191
++ Y+++I+ + +CH I+HRD+KP N++I+H +++ D+G+A F P + Y
Sbjct: 382 VKSYVFQIVTGIXFCHQRRIVHRDLKPQNLLINHTG-AIKIADFGMARTFALPVRAYTHE 558
Query: 192 VASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGT 251
V + +++ PE+L+ Y +D+WS+G + A M+ R P F G DQL +I +++GT
Sbjct: 559 VVTLWYRAPEILMGASKYSTPVDVWSIGTIFADMLIRT-PIFKGDSEIDQLFKIFRIIGT 735
Query: 252 EDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQS 311
+ + + + P FN + W+ SE + LD +++ L+ D
Sbjct: 736 PTEQTWPEFHKL---PAFNGMF-----PLWKEGKLSETLTDLDSLGLDLIERTLKCDPAQ 891
Query: 312 RLTAREAMEHPYFYTV 327
R++ ++ ++H YF V
Sbjct: 892 RISCKKMLQHAYFLNV 939
>14126
Length = 1265
Score = 104 bits (260), Expect = 6e-23, Method: Compositional matrix adjust.
Identities = 69/243 (28%), Positives = 122/243 (50%), Gaps = 10/243 (4%)
Frame = +3
Query: 92 PNIITLADIVKDPVSRTPA---LVFEHVNNTDFKQLYQT----LTDYDIRFYMYEILKAL 144
PN++ L D+ + ++ LVFE++ + L + L I+ M ++L +
Sbjct: 378 PNVVRLLDVSHNTITDREIRLNLVFEYIEHDLATYLAKCPSPGLGPDRIKDLMLQLLNGV 557
Query: 145 DYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLV 204
D+ HS I+HRD+KP N++I + R L+L D+GLA Y V + +++ PE+L+
Sbjct: 558 DFLHSNRIVHRDLKPQNLLISKDGR-LKLADFGLARIYSFHMALTTVVVTLWYRSPEVLM 734
Query: 205 DYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIE 264
+ Y S+D+WS GC+ A + F + F G +DQL +I +V+G D+ + ++
Sbjct: 735 QAE-YGTSVDIWSCGCIFAEL-FTRRALFKGSSEFDQLKKIFEVIGLPPAGDWPEGVSVH 908
Query: 265 LDPRFNDILGRHSRKRWERFVHSENQHLV---SPEALDFLDKLLRYDHQSRLTAREAMEH 321
R + Q LV P+A D ++K+L + R+++RE++ H
Sbjct: 909 -------------RNSFRPTPPVPLQTLVPEMDPQAKDLMEKMLVFKSGRRISSRESLLH 1049
Query: 322 PYF 324
PY
Sbjct: 1050PYL 1058
>01707
Length = 757
Score = 96.7 bits (239), Expect = 1e-20, Method: Compositional matrix adjust.
Identities = 63/223 (28%), Positives = 114/223 (51%), Gaps = 9/223 (4%)
Frame = +1
Query: 37 DDYQLVRKLGRGKYSEVFEAINITNNEXXXXXXXXXX-----XXXXXXXXXXXLENLRGG 91
+ Y+ + K+G G Y VF+ N ++ L+ L+
Sbjct: 64 EKYEKIGKIGEGSYGVVFKCRNKETSQLVAIKKFVESEDDPLIKKIAMREIRMLKQLKH- 240
Query: 92 PNIITLADIVKDPVSRTPALVFEHVNNTDFKQL---YQTLTDYDIRFYMYEILKALDYCH 148
PN++ L ++ + + LVF++V++T +L + L + ++ +Y+ L A+++CH
Sbjct: 241 PNLVRLIEVFRR--KKRLHLVFDYVDHTLLNELDRYPRGLPEPMVKRIIYQTLLAVNFCH 414
Query: 149 SMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFY-HPGQEYNVRVASRYFKGPELLVDYQ 207
+HRDVKP N++I + +++L D+G A PG EY VA+R+++ PELLV
Sbjct: 415 QYNTIHRDVKPENILITRQG-QVKLCDFGFARILTGPGDEYTDYVATRWYRAPELLVGDT 591
Query: 208 MYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLG 250
Y +D+W++GC+ A ++ + + G + DQL I K LG
Sbjct: 592 QYGPPVDVWAIGCVFAELL-TGQALWPGRSDVDQLHLIRKTLG 717
>04591
Length = 1117
Score = 89.7 bits (221), Expect = 2e-18, Method: Compositional matrix adjust.
Identities = 68/244 (27%), Positives = 117/244 (47%), Gaps = 10/244 (4%)
Frame = -2
Query: 93 NIITLADIV---KDPVSR---TPALVFEHVNNTDFKQLYQTL----TDYDIRFYMYEILK 142
N++ L +I P +R T L+FE+ + D L L + D + M ++L
Sbjct: 1038 NVVQLQEICHTQAGPYNRYKSTFYLIFEYCD-YDLAGLLNNLRVKFSLADKKNLMSQLLN 862
Query: 143 ALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPEL 202
L Y H+ I+HRD+K N+++ + L+L D+GL+ + + RV + +++ PEL
Sbjct: 861 GLFYIHTKQILHRDIKAANILLTRDG-VLKLADFGLSRPWVKSKRLTNRVVTLWYRPPEL 685
Query: 203 LVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYN 262
L+ + Y +DMW +GC++A M RK P G QL I + G+ + +
Sbjct: 684 LLGEREYGPEIDMWGVGCIMAEMWSRK-PLMQGRSEQHQLSLITDLCGSLNAEVWPGVTK 508
Query: 263 IELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHP 322
+EL + + G+ RK ER + L + E + +D LR D R+ A+ H
Sbjct: 507 LELYGKLDLPQGK-PRKVKERML----DLLKNKEGAELIDIFLRLDPGQRMNCDNALSHD 343
Query: 323 YFYT 326
+F+
Sbjct: 342 FFWV 331
>04138
Length = 800
Score = 87.0 bits (214), Expect = 1e-17, Method: Compositional matrix adjust.
Identities = 56/195 (28%), Positives = 101/195 (51%), Gaps = 6/195 (3%)
Frame = +1
Query: 144 LDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPG----QEYNVRVASRYFKG 199
L Y H I+HRD+K N++I + L+L D+GLA + Y RV + +++
Sbjct: 52 LYYIHRNKILHRDMKAANILITKQG-VLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRP 228
Query: 200 PELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLG--TEDLYDY 257
PELL+ + Y ++D W GC++A M + + P G +QL I ++ G T +++
Sbjct: 229 PELLLGDRNYSTAIDQWGAGCIMAEM-WTRNPIMQGTTEQNQLTLITQLCGSITPEVWPG 405
Query: 258 IDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTARE 317
+ + ++ + GR + R +RF + L P LD ++LL+ D R++A E
Sbjct: 406 VTQLSMYHQIKGALAAGRKNIIR-DRFA----RILKDPYGLDLFERLLKMDPSQRISADE 570
Query: 318 AMEHPYFYTVVKDQA 332
A+ H +F+ V+ ++
Sbjct: 571 ALNHDFFWVGVEPKS 615
>32000
Length = 644
Score = 85.9 bits (211), Expect = 3e-17, Method: Compositional matrix adjust.
Identities = 52/158 (32%), Positives = 81/158 (51%), Gaps = 3/158 (1%)
Frame = -1
Query: 170 KLRLIDWGLAE-FYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFR 228
K+++ D+GLA F P + Y V + +++ PE+L+ + Y +D+WSLGC+ M+ R
Sbjct: 575 KMKIADFGLARVFGLPVRTYTHEVITLWYRAPEILLGCRFYSVPVDIWSLGCIFVEMMTR 396
Query: 229 KEPFFHGHDNYDQLVRIAKVLGTED--LYDYIDKYNIELDPRFNDILGRHSRKRWERFVH 286
+ F G DQL RI + LGT D ++ + K P + + K E V
Sbjct: 395 RA-LFPGDSEIDQLYRIFRTLGTPDEKVWPGVSKL-----PDYKPTFPKWPLKNLETVVS 234
Query: 287 SENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYF 324
+S LD L ++L Y+ R++AR AM HPYF
Sbjct: 233 ------LSKVGLDLLKRMLTYNPNRRISARSAMRHPYF 138
>29581
Length = 1278
Score = 85.5 bits (210), Expect = 3e-17, Method: Compositional matrix adjust.
Identities = 67/253 (26%), Positives = 122/253 (48%), Gaps = 13/253 (5%)
Frame = -2
Query: 85 LENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTL----TDYDIRFYMYEI 140
L NLR NI+ L ++V + LV E+ D L + ++ ++ + ++
Sbjct: 1193 LLNLRHQ-NIVQLQEVVVGKSLDSLFLVMEYCEQ-DLASLLDNMPAPFSESQVKCIVLQL 1020
Query: 141 LKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFY-HPGQEYNVRVASRYFKG 199
LK L Y H I+HRD+K N+++ + +++ D+GLA Y P + +V + +++
Sbjct: 1019 LKGLRYLHEAFIIHRDLKVSNLLMT-DKGCVKIADFGLARNYGKPQKPMTPKVVTLWYRA 843
Query: 200 PELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTED------ 253
PELL + + ++DMWS GC+L ++ K P G + Q+ I ++LGT +
Sbjct: 842 PELLFGSKTHSTAIDMWSAGCILGELLGHK-PLMPGRSDLQQIELIMELLGTPNDTIWPG 666
Query: 254 --LYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQS 311
+++ ++ P +N++ RH+ W +S + L+ L Y Q
Sbjct: 665 FSQLPAFEQFTLKKQP-YNNL--RHTFP-W-----------LSESGIRLLNGLFMYHPQK 531
Query: 312 RLTAREAMEHPYF 324
R TA + +EH YF
Sbjct: 530 RATAEDCLEHSYF 492
>21079
Length = 878
Score = 76.6 bits (187), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 45/145 (31%), Positives = 78/145 (53%), Gaps = 5/145 (3%)
Frame = +1
Query: 92 PNIITLADIVKDPVSRTPALVFEHVNNTD-FKQLYQ---TLTDYDIRFYMYEILKALDYC 147
P ++ L D + P RT LV E V + F+++ + LT+ D ++ +I + Y
Sbjct: 4 PKLLMLWDAFEAP--RTMVLVMEFVGAGELFERVIRDDFVLTERDCVHFVRQICSGVGYM 177
Query: 148 HSMGIMHRDVKPHNVM-IDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDY 206
H+ I+H D+KP NV+ + ++++ID+GLA FY PG V + F PE +V+Y
Sbjct: 178 HTQSILHLDLKPENVLCVSDNSNQIKIIDFGLARFYKPGDSLQVLFGTPEFIAPE-VVNY 354
Query: 207 QMYDYSLDMWSLGCMLASMIFRKEP 231
+++ DMWS+G + ++ P
Sbjct: 355 DEINFTTDMWSIGVICYILLSGLSP 429
>01756
Length = 1858
Score = 76.3 bits (186), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 66/269 (24%), Positives = 114/269 (42%), Gaps = 19/269 (7%)
Frame = -3
Query: 2 SGPVPSRARVYTDVNTHRPREYWDYESHVVEWGNQD-DYQLVRKLGRGKYSEVFEAINIT 60
S SR R D + P YE+ + ++D Y+ + K+G+G + EVF+A
Sbjct: 1835 STASASREREQKDSQRYSP-----YETLKFPFCDEDAKYEKLAKIGQGTFGEVFKARCKK 1671
Query: 61 NNEXXXXXXXXXXXXXXXXXXXXXLE----NLRGGPNIITLADIVKDPVSRTPA------ 110
+ E L N++ L +I +
Sbjct: 1670 TKQVVAMKKVLMDNEKEGFPITALREIKILQLLNHENVVDLIEICSTKATSANRYKSMFY 1491
Query: 111 LVFEHVNNTDFKQLYQTLTDY----DIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDH 166
LVFE + D L ++ +I+ M +++ L Y H I+HRD+K N++I
Sbjct: 1490 LVFEFCEH-DLAGLLSNMSVVFNLPEIKEVMKQLMNGLYYIHRNKILHRDMKAANILITK 1314
Query: 167 EHRKLRLIDWGLAEFYHPG----QEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCML 222
+ L+L D+GLA + Y RV + +++ PELL+ + Y ++D W GC++
Sbjct: 1313 QG-VLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRPPELLLGDRNYSTAIDQWGAGCIM 1137
Query: 223 ASMIFRKEPFFHGHDNYDQLVRIAKVLGT 251
A M + + P G +QL I ++ G+
Sbjct: 1136 AEM-WTRNPIMQGTTEQNQLTLITQLCGS 1053
>15910
Length = 1361
Score = 70.9 bits (172), Expect = 8e-13, Method: Compositional matrix adjust.
Identities = 54/202 (26%), Positives = 91/202 (45%), Gaps = 2/202 (0%)
Frame = +2
Query: 129 TDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMID--HEHRKLRLIDWGLAEFYHPGQ 186
T+ D + +IL + Y H+ G++HRD+KP N++ + + KL+L D+GL+ P
Sbjct: 458 TEKDAARAISDILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLADFGLSRIIEPEV 637
Query: 187 EYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIA 246
+ + + + PE+L + Y S+DMWS+G + ++ EPFF ++
Sbjct: 638 QMSTVCGTPGYCAPEVLKGDK-YTPSVDMWSVGVIAYILLCGYEPFFAENEF-------- 790
Query: 247 KVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLR 306
++Y I K + D + W +S A D + KLL
Sbjct: 791 ------EMYRKIIKGEYKFDEEY-----------WSE---------ISENAKDVVRKLLV 892
Query: 307 YDHQSRLTAREAMEHPYFYTVV 328
D + RLTA EA+ P+ V
Sbjct: 893 IDPKKRLTATEALRLPWVKGVA 958
>26560
Length = 398
Score = 69.3 bits (168), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 36/108 (33%), Positives = 64/108 (59%)
Frame = -1
Query: 125 YQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHP 184
+ T+ ++RFY E++ L++ HS +++RD+KP N+++D E+ +R+ D GLA +
Sbjct: 374 HGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLD-ENGHVRISDLGLACDFSK 198
Query: 185 GQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPF 232
+ + V + + PE+L+ Q YD S D +S GCML ++ PF
Sbjct: 197 KRPH-ASVGTHGYMAPEVLMKGQSYDSSADWFSFGCMLYKLLKGHSPF 57
>23319
Length = 2235
Score = 68.9 bits (167), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 42/120 (35%), Positives = 60/120 (50%), Gaps = 2/120 (1%)
Frame = +3
Query: 207 QMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLG--TEDLYDYIDKYNIE 264
+MY S+DMWS GC+ A + P F G+D+ DQL RI K+LG TED + + +
Sbjct: 21 KMYSTSIDMWSAGCIFAELANAGRPLFPGNDDDDQLKRIFKLLGTPTEDQWPGMTQL--- 191
Query: 265 LDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYF 324
P + H W++ V N + D L LL R++A EA++HPYF
Sbjct: 192 --PNYRMFPMYHVTTTWQQVVPKLNS-----KGRDLLQCLLVCCPSDRMSADEALQHPYF 350
>12721
Length = 821
Score = 62.0 bits (149), Expect = 4e-10, Method: Compositional matrix adjust.
Identities = 33/95 (34%), Positives = 57/95 (60%), Gaps = 1/95 (1%)
Frame = +1
Query: 141 LKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGL-AEFYHPGQEYNVRVASRYFKG 199
LKAL + H+ G++HRD+K ++++ H+ K++L D+G A+ Q+ V + Y+
Sbjct: 403 LKALAFLHANGVIHRDIKSDSILLSHDG-KVKLXDFGFCAQVTQDLQKRKSLVGTPYWMA 579
Query: 200 PELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFH 234
PE++ Y +D+WSLG M+ MI + PFF+
Sbjct: 580 PEVISRLP-YGPEVDIWSLGIMVMEMIDAEPPFFN 681
>00300
Length = 2318
Score = 62.0 bits (149), Expect = 4e-10, Method: Compositional matrix adjust.
Identities = 53/226 (23%), Positives = 104/226 (46%), Gaps = 18/226 (7%)
Frame = -1
Query: 39 YQLVRKLGRGKYSEVFEAINITNNEXXXXXXXXXXXXXXXXXXXXXLENLRGGPNIITLA 98
+Q K+G G++ +V+ A+N++ E L+ LR + I +
Sbjct: 1652 WQRGNKIGEGQFGKVYTAVNMSTGELMALKEMKFQPND--------LQQLREMCDEIKIF 1497
Query: 99 DIVKDP---------VSRTPALVF-EHVNNTDFKQLYQ-TLTDYDIRFYMYEILKALDYC 147
+ ++ V + L+F E+ + ++ + L +Y IR Y EI+ A+++
Sbjct: 1496 EGIQHENLVKYYGVEVHKDEMLMFMEYCDTGTIEEAAKMGLPEYLIRRYTREIVLAVNHL 1317
Query: 148 HSMGIMHRDVKPHNVMIDHEHRKLRLIDWGL-----AEFYHPGQEYNVRVASRYFKGPEL 202
H I+HRD+K N+ + + ++L D+G + PG+ +N+ V + + PE+
Sbjct: 1316 HENSIVHRDIKGANIFLT-SNGHVKLGDFGCSVKLKSHTTMPGEFHNL-VGTTAYMAPEV 1143
Query: 203 LV--DYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIA 246
D Y + D+WSLGC++ M K P+ +NY + ++
Sbjct: 1142 FTQNDQGGYGRAADIWSLGCVVIEMATGKRPWHDLDNNYQIMYKVG 1005
>12786
Length = 460
Score = 61.6 bits (148), Expect = 6e-10, Method: Compositional matrix adjust.
Identities = 43/142 (30%), Positives = 71/142 (50%), Gaps = 22/142 (15%)
Frame = -3
Query: 126 QTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPG 185
Q L I+FY E+L+A+ H+ G++H D+KP N M+ + L+LID+G+A
Sbjct: 425 QGLDRMMIKFYWREMLRAVKALHNEGVIHSDLKPANFMLVAGN--LKLIDFGIANTLQQD 252
Query: 186 QEY---NVRVASRYFKGPELLV-------DYQM----------YDYSL--DMWSLGCMLA 223
+ + RV + + PE ++ D M Y + D+WSLGC+L
Sbjct: 251 KTSVLKDSRVGTPSYMSPEAIMAACDDSADDSMEEDGHRTKPKYKVGVRSDVWSLGCILY 72
Query: 224 SMIFRKEPFFHGHDNYDQLVRI 245
+M++ + PF H +N +L I
Sbjct: 71 NMVYGRTPFQHIKNNMGKLQAI 6
>13212
Length = 1067
Score = 61.6 bits (148), Expect = 6e-10, Method: Compositional matrix adjust.
Identities = 53/208 (25%), Positives = 89/208 (42%), Gaps = 7/208 (3%)
Frame = -1
Query: 124 LYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVM--IDHEHRKLRLIDWGL-AE 180
L + +T+ I + +E+ ALD+ H ++HRD+K NV+ ID E ++L D+G+ A+
Sbjct: 1001 LEKPMTEAQICYVCHEMCMALDFLHRHHVIHRDIKAGNVLLTIDGE---VKLADFGVSAK 831
Query: 181 FYHPGQEYNVRVASRYFKGPELLVDYQM----YDYSLDMWSLGCMLASMIFRKEPFFHGH 236
Q+ + + + Y+ PE+++ + YD+ D+WSLG L + P H
Sbjct: 830 NTQTQQKRDTFIGTPYWMAPEVVLCETLKDTPYDFKADIWSLGVTLIEFAQIEPPNKEMH 651
Query: 237 DNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPE 296
L++I K +D K+W +
Sbjct: 650 -PMRVLIKIHK----------------------SDPPTLEKPKKWTKLFK---------- 570
Query: 297 ALDFLDKLLRYDHQSRLTAREAMEHPYF 324
DF+ K L D R TA E +EHP+
Sbjct: 569 --DFIAKCLVKDPNLRPTAAELLEHPFM 492
>01392
Length = 1806
Score = 60.5 bits (145), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 56/211 (26%), Positives = 88/211 (41%), Gaps = 12/211 (5%)
Frame = -1
Query: 128 LTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDH--EHRKLRLIDWGLAEFYH-- 183
L + + + I +ALD+ HS GI HRD+KP N++ +H + +++ D+ LA
Sbjct: 1800 LCEREASLVVRHIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGISCD 1621
Query: 184 ----PGQEYNVRVASRYFKGPEL----LVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHG 235
E V S + PE+ + D YD D+WSLG +L M+ PF
Sbjct: 1620 GDGTKTPELLTPVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILYIMLCGYPPF--- 1450
Query: 236 HDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSP 295
Y Q E +D D FN I H + S+ +S
Sbjct: 1449 ---YGQCGEDCGWNRGEACHDCQDML-------FNSIQDGHYK------FPSQEWTSISS 1318
Query: 296 EALDFLDKLLRYDHQSRLTAREAMEHPYFYT 326
A D + LL + + R +A + ++HP+ T
Sbjct: 1317 SAKDLIRHLLVREPRKRYSAADVLKHPWICT 1225
>28638
Length = 1458
Score = 60.1 bits (144), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 28/77 (36%), Positives = 48/77 (62%), Gaps = 1/77 (1%)
Frame = -1
Query: 150 MGIMHRDVKPHNVMIDHEHRK-LRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQM 208
M I+H D+KP N+++ + R ++++D+G GQ + SR+++ PE+L+
Sbjct: 774 MNIIHCDLKPENILLCNPKRSAIKIVDFG--SSCQLGQRIYQYIQSRFYRSPEVLLGVP- 604
Query: 209 YDYSLDMWSLGCMLASM 225
YD ++DMWSLGC+L M
Sbjct: 603 YDLAIDMWSLGCILVEM 553
Score = 32.3 bits (72), Expect = 0.29, Method: Compositional matrix adjust.
Identities = 32/141 (22%), Positives = 60/141 (42%), Gaps = 32/141 (22%)
Frame = -2
Query: 216 WSLGCMLASMIFRK----EPFFHGHDNYDQLVRIAKVLG------------TEDLYDYI- 258
W L C ++ + + P F G + +DQ+++I +VLG T +D +
Sbjct: 596 WPLTCGXWAVYWWRCTXGNPLFAGSNEFDQMMKIVEVLGVPPRHILDQAQKTRKYFDLLP 417
Query: 259 ------------DKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLR 306
KY + +++LG R + E H V+ + L F D +LR
Sbjct: 416 DGTYAPKKPRDNKKYKSPSSRKLHEVLGAEKGGPGGRRM-GEPGHTVA-DYLKFKDLILR 243
Query: 307 ---YDHQSRLTAREAMEHPYF 324
+D ++R++ A++H +F
Sbjct: 242 MLDFDPKTRISPYYALQHNFF 180
>30755
Length = 1137
Score = 60.1 bits (144), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 39/123 (31%), Positives = 65/123 (52%), Gaps = 2/123 (1%)
Frame = +2
Query: 128 LTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLA-EFYHPGQ 186
T+ RFY EI+ AL Y HS GI++RD+K N+++D + +++ D+GL E G+
Sbjct: 23 FTEERTRFYGAEIISALGYLHSQGIIYRDLKLENLLLDKDGH-IKVADFGLCKEDITYGR 199
Query: 187 EYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFH-GHDNYDQLVRI 245
+ + PE+L D Y ++D W G ++ MI + PF++ HD L+ +
Sbjct: 200 TTKTFCGTPEYLAPEVLDDND-YGRAVDWWGTGVVMYEMICGRLPFYNRDHDVLFTLILV 376
Query: 246 AKV 248
V
Sbjct: 377 EDV 385
>01966
Length = 1735
Score = 59.3 bits (142), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 37/136 (27%), Positives = 72/136 (52%), Gaps = 7/136 (5%)
Frame = -1
Query: 93 NIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQ------TLTDYDIRFYMYEILKALDY 146
NI+ L D++ + LVFE ++ D K L ++ Y+++I+ +++
Sbjct: 1531 NIVCLEDVIME--DERLFLVFEFLS-MDLKMYIDKFPEGVVLDRRLVKSYVFQIVTGINF 1361
Query: 147 CHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAE-FYHPGQEYNVRVASRYFKGPELLVD 205
CH I+HRD+KP N++I+H +++ D+G+A F P + Y V + +++ PE+L+
Sbjct: 1360 CHQRRIVHRDLKPQNLLINHTG-AIKIADFGMARTFALPVRAYTHEVVTLWYRAPEILMG 1184
Query: 206 YQMYDYSLDMWSLGCM 221
Q + W+ G +
Sbjct: 1183 PQ---STPPXWTCGAL 1145
Score = 57.4 bits (137), Expect = 9e-09, Method: Compositional matrix adjust.
Identities = 32/119 (26%), Positives = 58/119 (48%)
Frame = -3
Query: 209 YDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPR 268
Y +D+WS+G + A M+ R P F G DQL +I +++GT + + + + P
Sbjct: 1175 YSTPVDVWSIGTIFADMLIRT-PIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKL---PA 1008
Query: 269 FNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTV 327
FN + W+ SE + LD +++ L+ D R++ ++ ++H YF V
Sbjct: 1007 FNGMF-----PLWKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYFLNV 846
>14420
Length = 528
Score = 58.2 bits (139), Expect = 6e-09, Method: Compositional matrix adjust.
Identities = 30/97 (30%), Positives = 55/97 (56%), Gaps = 1/97 (1%)
Frame = +2
Query: 139 EILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQ-EYNVRVASRYF 197
E L+AL++ H ++HRD+K N+++ + ++L D+G P Q + + V + Y+
Sbjct: 221 ECLQALEFLHENQVIHRDIKSDNILLGMDG-SVKLTDFGFCAQLSPEQSKRSTMVGTPYW 397
Query: 198 KGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFH 234
PE++ Q Y ++D+WSLG M MI + P+ +
Sbjct: 398 MAPEVVTRKQ-YGPTVDIWSLGVMCIEMIEGEPPYLN 505
>27405
Length = 532
Score = 57.4 bits (137), Expect = 8e-09, Method: Compositional matrix adjust.
Identities = 35/128 (27%), Positives = 67/128 (52%), Gaps = 3/128 (2%)
Frame = -3
Query: 90 GGPNIITLADIVKDPVSRTPALVFEHVNNTDFK---QLYQTLTDYDIRFYMYEILKALDY 146
G P I+ + + P + + +N D + T+ ++RFY E++ L++
Sbjct: 380 GSPFIVCMTYAFQTP--EKLCFILDLMNGGDLHYHLSQHGVFTEKEVRFYAAEVMLGLEH 207
Query: 147 CHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDY 206
HS +++RD+KP N+++D E+ +R+ D GLA + ++ + V + + PE+L+
Sbjct: 206 MHSRFVVYRDLKPANILLD-ENGHVRISDLGLACDFSK-KKPHASVGTHGYMAPEVLMKG 33
Query: 207 QMYDYSLD 214
Q YD S D
Sbjct: 32 QAYDSSAD 9
>18921
Length = 697
Score = 57.4 bits (137), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 34/110 (30%), Positives = 57/110 (51%), Gaps = 1/110 (0%)
Frame = +2
Query: 126 QTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLA-EFYHP 184
+TL + +I +Y LK L Y HS +HRD+K N+++++E +L D+G+A +
Sbjct: 302 KTLVEREIATILYYTLKGLXYLHSRRKIHRDIKAGNILLNNEGHA-KLADFGVAGQLTDT 478
Query: 185 GQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFH 234
+ N + + Y+ PE++ + YD D+WSLG M K P
Sbjct: 479 MAKRNTVIGTPYWMAPEVIQEIG-YDCVADIWSLGITALEMAEGKPPVME 625
>26711
Length = 405
Score = 55.8 bits (133), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 28/95 (29%), Positives = 53/95 (55%), Gaps = 1/95 (1%)
Frame = -2
Query: 139 EILKALDYCHSMGIMHRDVKPHNVMIDHEH-RKLRLIDWGLAEFYHPGQEYNVRVASRYF 197
++L L + H+ G++H D+KP N+++ + ++LID+GLA +P QE + + F
Sbjct: 392 QVLDILQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARKLYPPQETFLNHGTPGF 213
Query: 198 KGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPF 232
PE L D + + D+W +G + ++ + PF
Sbjct: 212 TSPEAL-DVKPISTASDVWGVGVLAYILLSGQSPF 111
>03294
Length = 1684
Score = 55.8 bits (133), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 31/117 (26%), Positives = 58/117 (49%)
Frame = -1
Query: 211 YSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFN 270
+ +D+WS+G + A M+ R P F G DQL +I +++GT + + + + P FN
Sbjct: 1678 HPVDVWSIGTIFADMLIRT-PIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKL---PAFN 1511
Query: 271 DILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTV 327
+ W+ SE + LD +++ L+ D R++ ++ ++H YF V
Sbjct: 1510 GMF-----PLWKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYFLNV 1355
>19761
Length = 473
Score = 55.8 bits (133), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 38/125 (30%), Positives = 62/125 (49%), Gaps = 3/125 (2%)
Frame = -3
Query: 133 IRFYMYEILKALDYCHSMG--IMHRDVKPHNVMIDHEHRKLRLIDWGLA-EFYHPGQEYN 189
I ++ + AL+Y H+ I+HRD+KP N+ + E +RL D GLA + P
Sbjct: 417 IVCWLMQTASALNYMHTHTPVILHRDLKPQNIYVT-EKGDVRLGDLGLARKLTGPADFAT 241
Query: 190 VRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVL 249
+V + + PE+L Q Y+ D+WSLGC+ + +K G D + + +V+
Sbjct: 240 SQVGTIMYLSPEIL-SQQPYNSKSDIWSLGCVFYDITGKK-----GSDEMGVMFLLVQVM 79
Query: 250 GTEDL 254
G L
Sbjct: 78 GGRKL 64
>31885
Length = 529
Score = 55.8 bits (133), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 29/104 (27%), Positives = 55/104 (52%), Gaps = 4/104 (3%)
Frame = -2
Query: 133 IRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRV 192
++FY+ ++ LDY S I+HRD+KP N+++D E + D+ +A +
Sbjct: 366 VKFYLCQLALVLDYLRSQKIVHRDIKPDNILLD-EQGHCHVTDFNIATQLEDDELATSTS 190
Query: 193 ASRYFKGPEL----LVDYQMYDYSLDMWSLGCMLASMIFRKEPF 232
+R + PE+ + + + Y + +D WSLG L ++ ++ PF
Sbjct: 189 GTRPYMAPEVYGVAINERRGYGFPVDWWSLGVSLFELLKKRRPF 58
>18484
Length = 635
Score = 55.1 bits (131), Expect = 5e-08, Method: Compositional matrix adjust.
Identities = 35/104 (33%), Positives = 55/104 (52%), Gaps = 6/104 (5%)
Frame = +1
Query: 135 FYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVAS 194
FY EI L + H GI++RD+K NVM+D E +++ D+G+ + G +
Sbjct: 55 FYAAEIAVGLFFLHDQGIIYRDLKLDNVMLDSEGH-IKIADFGMCKEGMTGD-----ATT 216
Query: 195 RYFKG------PELLVDYQMYDYSLDMWSLGCMLASMIFRKEPF 232
R F G PE+++ YQ Y S+D W+ G +L M+ + PF
Sbjct: 217 RTFCGTPDYIAPEIVL-YQPYSKSVDWWAYGVLLFEMLAGQPPF 345
>09606
Length = 1300
Score = 54.7 bits (130), Expect = 6e-08, Method: Compositional matrix adjust.
Identities = 54/222 (24%), Positives = 91/222 (40%), Gaps = 25/222 (11%)
Frame = -3
Query: 128 LTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAE------- 180
L + IR + ++ L Y HS+GI+ D++P V++D L+ D+GL++
Sbjct: 842 LPETSIRDFGIHLVTGLHYIHSLGILFHDLRPSKVLLD-TSGVLKFADFGLSKVEGENLE 666
Query: 181 -----FYHPGQEYNVRVASRYFK-----------GPELLVDYQMYDYSL--DMWSLGCML 222
F G ++N++ A K PE+ +Q + S+ D+W+LGC+
Sbjct: 665 ELFFKFAEAGDQWNIQSAEEMMKQVPTSGSPTYMAPEV---FQGAEPSIMSDLWALGCVF 495
Query: 223 ASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWE 282
M F P F G + YD + KVL E + + P
Sbjct: 494 YEM-FSGHPPFLG-ETYD--ITKDKVLNKEFPLPKVKGSRLSAKP--------------- 372
Query: 283 RFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYF 324
SPE L+ L+ LL+ D RL+ ++H ++
Sbjct: 371 -----------SPEFLNLLESLLQKDSTRRLSWASLVKHAFW 279
>18287
Length = 678
Score = 54.3 bits (129), Expect = 8e-08, Method: Compositional matrix adjust.
Identities = 35/119 (29%), Positives = 63/119 (52%), Gaps = 3/119 (2%)
Frame = -3
Query: 209 YDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGT---EDLYDYIDKYNIEL 265
YDYS+D+WS+GC+ A ++ R+ F QL I ++GT ED+ +
Sbjct: 673 YDYSIDIWSVGCIFAELLSRRI-LFQAQGPVQQLDMIINLVGTPRPEDMERACEGAR--- 506
Query: 266 DPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYF 324
N IL + R++ +++ + H + EA+ L ++L + ++R++A EA+ HPY
Sbjct: 505 ----NHILNQPFRRQNLLTLYNLSPH-ATHEAVRLLTRMLILNPKNRISAEEALSHPYL 344
>19094
Length = 898
Score = 53.9 bits (128), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 32/101 (31%), Positives = 55/101 (54%), Gaps = 1/101 (0%)
Frame = +1
Query: 126 QTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLA-EFYHP 184
+TL + +I +Y LK L Y HS +HRD+K N+++++E +L D+G+A +
Sbjct: 43 KTLVEREIATILYYTLKGL*YLHSRRKIHRDIKAGNILLNNEGHA-KLADFGVAGQLTDT 219
Query: 185 GQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASM 225
+ N + + Y+ PE++ + YD D+WSLG M
Sbjct: 220 MAKRNTVIGTPYWMAPEVIQEIG-YDCVADIWSLGITALEM 339
>13592
Length = 980
Score = 53.5 bits (127), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 63/296 (21%), Positives = 114/296 (38%), Gaps = 16/296 (5%)
Frame = +2
Query: 44 KLGRGKYSEVFEAINITNNEXXXXXXXXXX--XXXXXXXXXXXLENLRGGPNIITLADIV 101
K+G+G++ +V+ A+N E L+ L G I ++V
Sbjct: 5 KIGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETRALKNVAEELKILEG----IKHKNLV 172
Query: 102 K---DPVSRTPALVFEHVNNT----DFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMH 154
+ V R L+F + + +L L + R + ++L + H GI+H
Sbjct: 173 RYYGIEVHREELLIFMELCSEGTLESLVELTGGLPEALSRRFTAQLLSGVAELHKHGIVH 352
Query: 155 RDVKPHNVMIDHEHRKLRLIDWGLAEFYH-----PGQEYNVRVASRYFKGPELLVDYQMY 209
RD+K N+ + L+L D+G A PG E V ++ + PE+
Sbjct: 353 RDIKTANIFLVDGSNSLKLGDFGSAVKIQAHTTVPG-ELQGYVGTQAYMAPEVFTKTNSD 529
Query: 210 DYS--LDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDP 267
+ D+WS+GC++ M K P+ N+ + ++ +G + P
Sbjct: 530 GHGRLADIWSVGCVVVEMASGKRPWAQFDSNFQIMFKVG--MGEK--------------P 661
Query: 268 RFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPY 323
+ + L S E DF+D L++D + RL+A E +E +
Sbjct: 662 QAPESL--------------------SQEGHDFIDHCLQHDPKQRLSAIELLEQNF 769
>18401
Length = 463
Score = 50.8 bits (120), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 35/143 (24%), Positives = 75/143 (52%), Gaps = 10/143 (6%)
Frame = -3
Query: 192 VASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGT 251
V++R+++ PE++++ + + D+WS+GC++ ++ F HDN + L + ++LG+
Sbjct: 449 VSTRHYRAPEVILELG-WSHPCDVWSVGCIMFE-LYTGYTLFQTHDNKEHLAMMERILGS 276
Query: 252 EDLYDYIDK-------YNIELDPRFNDILGRHSRKRWE---RFVHSENQHLVSPEALDFL 301
Y K ++ LD + R+ R+ + R+V + ++ + D +
Sbjct: 275 LP-YRMAKKTKKQKYFHHGRLDVPERSSMARYVRENTKPLLRYV-KDRENKDHQQLFDLM 102
Query: 302 DKLLRYDHQSRLTAREAMEHPYF 324
KLL Y+ SR + +A++HP+F
Sbjct: 101 KKLLAYEASSRYSLLQALQHPFF 33
>03240
Length = 1683
Score = 50.4 bits (119), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 36/145 (24%), Positives = 57/145 (39%), Gaps = 45/145 (31%)
Frame = -3
Query: 134 RFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGL--------------- 178
RFY+ E+++A++ H MG +HRD+KP N++ID ++L D+GL
Sbjct: 982 RFYVAELVQAIESVHRMGFIHRDIKPDNILIDRNGH-IKLTDFGLCTGFRWTHNSKYYQR 806
Query: 179 ---------------------AEFYHPGQEYNVR---------VASRYFKGPELLVDYQM 208
E P + R V + + PE+L
Sbjct: 805 DGTHARQDSMEVKCQLDEQCQCEILKPLERRRKREQRCLAHSLVGTPNYIAPEVLSRLGG 626
Query: 209 YDYSLDMWSLGCMLASMIFRKEPFF 233
Y D WS+G +L M+ PF+
Sbjct: 625 YTSVCDWWSVGVILFEMLVGHPPFY 551
>21433
Length = 590
Score = 49.3 bits (116), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 43/172 (25%), Positives = 76/172 (44%)
Frame = +2
Query: 136 YMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASR 195
Y+Y++ AL+YCH ++HRD+KP N+++ L++ D+G + + P +
Sbjct: 182 YIYQLSSALEYCHYRKVIHRDIKPENLLLG-LKGDLKIADFGWS-VHAPSSRRTTMCGTL 355
Query: 196 YFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLY 255
+ PE +V+ + +D ++D+WSLG + Y+ LV GT L
Sbjct: 356 DYLPPE-MVEGKTHDENVDLWSLGVLC----------------YEFLV------GTPPLR 466
Query: 256 DYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRY 307
+ PR+ S + +V+P A D + KLLR+
Sbjct: 467 PSPTRPPTPASPRWT----------------SGSPSIVTPGARDLISKLLRH 574
>13078
Length = 773
Score = 47.8 bits (112), Expect = 8e-06, Method: Compositional matrix adjust.
Identities = 37/126 (29%), Positives = 61/126 (48%), Gaps = 14/126 (11%)
Frame = -1
Query: 213 LDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDK-------YNIEL 265
D+WS+GC++ ++ F HDN + L + ++LG+ Y K Y+ L
Sbjct: 734 CDVWSIGCIMFE-LYTGYTLFQTHDNKEHLAMMERILGSLP-YRMAKKTKKQKYFYHGRL 561
Query: 266 DPRFNDILGRHSR---KRWERFV----HSENQHLVSPEALDFLDKLLRYDHQSRLTAREA 318
D GR+ R K R+V + ++Q L D +DK+L Y+ +R + R+A
Sbjct: 560 DWDEKSSAGRYVRDNVKPLRRYVKDPDNEDHQQL-----FDLMDKMLSYEVSTRYSLRQA 396
Query: 319 MEHPYF 324
M HP+F
Sbjct: 395 MRHPFF 378
>31489
Length = 329
Score = 47.4 bits (111), Expect = 9e-06, Method: Compositional matrix adjust.
Identities = 27/77 (35%), Positives = 49/77 (63%), Gaps = 6/77 (7%)
Frame = +3
Query: 93 NIITLADIVKDPVS----RTPALVFEHVNNTDFKQLY--QTLTDYDIRFYMYEILKALDY 146
NII++ +I+K S + +VF+ + + + +Y Q LT+ IR+++Y+IL+ L Y
Sbjct: 33 NIISIREILKPKDSYHDFKDIHVVFDLMESDLHRIIYSDQPLTEEHIRYFLYQILRGLKY 212
Query: 147 CHSMGIMHRDVKPHNVM 163
HS ++HRD+KP N++
Sbjct: 213 IHSANVVHRDLKPSNLL 263
>13066
Length = 551
Score = 47.4 bits (111), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 27/90 (30%), Positives = 45/90 (50%), Gaps = 4/90 (4%)
Frame = +3
Query: 134 RFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGL--AEFYHPGQEYNVR 191
+ + Y++ AL+Y HS + HRD+K N+++ H ++L D+G A G++Y R
Sbjct: 285 KIWFYQMTTALNYLHSYDVAHRDLKCENILLS-SHFNVKLADFGFACACITESGEKYMSR 461
Query: 192 --VASRYFKGPELLVDYQMYDYSLDMWSLG 219
S + PE++ D WSLG
Sbjct: 462 TYCGSAAYAAPEIVYGAPYAPKVADAWSLG 551
>04852
Length = 1462
Score = 45.8 bits (107), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 28/90 (31%), Positives = 46/90 (51%), Gaps = 3/90 (3%)
Frame = +1
Query: 136 YMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASR 195
Y ++I + +++ S +HRD+ NV++ EH L++ D+GL+ G Y R R
Sbjct: 340 YAFQIARGMEFLASRKCIHRDLAARNVLVTEEH-VLKIADFGLS---RTGDYYKKRSGGR 507
Query: 196 Y---FKGPELLVDYQMYDYSLDMWSLGCML 222
+ PE L D + Y D+WS G +L
Sbjct: 508 LPVKWMAPEALFDMR-YTTKSDVWSFGVVL 594
>07940
Length = 1336
Score = 45.4 bits (106), Expect = 4e-05, Method: Compositional matrix adjust.
Identities = 29/105 (27%), Positives = 56/105 (53%), Gaps = 4/105 (3%)
Frame = -3
Query: 122 KQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLA-- 179
+ + + LT D+ Y Y++ + ++Y S +HRD+ NV++ E+ L++ D+GL
Sbjct: 374 QDMLKMLTPKDLISYAYQVARGMEYLASKQCIHRDLAARNVLVAEEY-VLKIADFGLTRN 198
Query: 180 --EFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCML 222
+F + + + R+ ++ PE L D + Y D+WS G +L
Sbjct: 197 LQQFDYYRKTTDGRLPVKWM-APEALFDRK-YTSKSDVWSYGVLL 69
>11185
Length = 473
Score = 45.1 bits (105), Expect = 5e-05, Method: Compositional matrix adjust.
Identities = 31/120 (25%), Positives = 55/120 (45%), Gaps = 25/120 (20%)
Frame = +1
Query: 132 DIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAE----------- 180
IR + ++ L Y HS+GI+ D++P V++D L+ D+GL++
Sbjct: 4 SIRDFGIHLVTGLHYIHSLGILFHDLRPSKVLLD-TSGVLKFADFGLSKVEGENLEELFF 180
Query: 181 -FYHPGQEYNVRVASRYFK-----------GPELLVDYQMYDYSL--DMWSLGCMLASMI 226
F G ++N++ A K PE+ +Q + S+ D+W+LGC+ M
Sbjct: 181 KFAEAGDQWNIQSAEEMMKQVPTSGSPTYMAPEV---FQGAEPSIMSDLWALGCVFYEMF 351
>00715
Length = 1788
Score = 44.3 bits (103), Expect = 7e-05, Method: Compositional matrix adjust.
Identities = 38/149 (25%), Positives = 63/149 (42%), Gaps = 27/149 (18%)
Frame = +1
Query: 111 LVFEHVNNTDFKQL---YQTLTDYDIRFYM-YEILKALDYCHSMGIMHRDVKPHNVMIDH 166
L E+V + + + +Q D +R + ++ + L Y HS+ I+H D+KP N ++
Sbjct: 166 LAMEYVGPLNLQTILNDHQQDIDSSMRLSLALQMARGLHYLHSINIVHLDLKPANCLLTR 345
Query: 167 EHRKLRLIDWGLAEFYHP-----------------------GQEYNVRVASRYFKGPELL 203
+ KLR+ D+G P G N + ++ PELL
Sbjct: 346 D-LKLRIADFGCCHQLTPTGLDMGEREGGMAGNELELTPVQGAWKNELAGTLAYRAPELL 522
Query: 204 VDYQMYDYSLDMWSLGCMLASMIFRKEPF 232
Q S D++SLG L M R+ P+
Sbjct: 523 KGLQPSVRS-DVYSLGITLWQMCTRQGPY 606
>17975
Length = 449
Score = 42.4 bits (98), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 16/44 (36%), Positives = 30/44 (68%)
Frame = +3
Query: 136 YMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLA 179
Y +I++A+ YCH + ++HRD+KP NV+ + ++L D+G +
Sbjct: 282 YFRQIVEAISYCHKLHVVHRDLKPENVVFFEKPGLVKLTDFGFS 413
>37602
Length = 804
Score = 40.8 bits (94), Expect = 8e-04, Method: Compositional matrix adjust.
Identities = 26/90 (28%), Positives = 40/90 (44%), Gaps = 3/90 (3%)
Frame = -1
Query: 111 LVFEHVNNTDFKQLYQT---LTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHE 167
+ E+ + +Y LT+ I F E LK L Y H G MHRD+K N+++ E
Sbjct: 288 IAMEYCGGGSMQDIYHVTGPLTEPQIAFVCRETLKGLHYLHRRGKMHRDIKGANILLTEE 109
Query: 168 HRKLRLIDWGLAEFYHPGQEYNVRVASRYF 197
D LA+F+ ++ V + F
Sbjct: 108 G------DVKLADFWRVSSNHSHNVQKKVF 37
>01718
Length = 959
Score = 40.8 bits (94), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 49/218 (22%), Positives = 90/218 (41%), Gaps = 9/218 (4%)
Frame = +3
Query: 20 PREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEXXXXXXXXXXXXXXXX 79
P+ H V + D + K+G G +SEVF+ + +
Sbjct: 96 PKSSCQALRHAVSALTRLDDFICEKIGAGFFSEVFKVTHRITGQVMALKMNTMTSNRHNM 275
Query: 80 XXXXXLENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTD---YDIRFY 136
L N NI+ + + AL E++ + + +QL + + + R
Sbjct: 276 LREVQLLNRLQHANILRFMGVCVHE-GQLHALT-EYIPSGNLEQLLEKKDEELPWTQRIQ 449
Query: 137 M-YEILKALDYCHSMGIMHRDVKPHNVMI---DHEHRKLRLIDWGLA-EFYHP-GQEYNV 190
+ + + LDY HS +HRD+ N++I D+ + D+GLA + P +E
Sbjct: 450 LTLGLARGLDYLHSTRFIHRDLTSKNILIRREDNHGYHAVIADFGLATKIPDPLDKEKLP 629
Query: 191 RVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFR 228
V S Y+ PE+L + Y+ D++S+G ++ + R
Sbjct: 630 TVGSPYWMAPEVL-NGHFYNERADLFSVGIIMCEITAR 740
>14116
Length = 1017
Score = 40.4 bits (93), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 27/105 (25%), Positives = 51/105 (48%), Gaps = 5/105 (4%)
Frame = -1
Query: 129 TDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLA-----EFYH 183
T D+ Y +I + +DY + +HRD+ N M+D E +++ D+GLA + Y+
Sbjct: 327 TIKDLIMYGVDIARGMDYLAGLKFVHRDLAARNCMLD-EDFHVKVADFGLARDIYEKEYY 151
Query: 184 PGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFR 228
+ ++ ++ L + YD D+WS G +L ++ R
Sbjct: 150 SSENKKAKLPVKWMALESL--EKGNYDSKTDVWSYGVVLWELLTR 22
>01106
Length = 878
Score = 39.7 bits (91), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 38/163 (23%), Positives = 68/163 (41%), Gaps = 18/163 (11%)
Frame = +3
Query: 20 PREYWDYESHVVEWGN--QDDYQLVRKLGRGKYSEV----------FEAINITNNEXXXX 67
PR+Y H V+ G+ Y ++RKLG G +S V F A+ + +
Sbjct: 261 PRDYCKGGYHPVKNGDLFNGRYHVIRKLGWGHFSTVWLCWDLTCKRFVALKVVKSAQHYT 440
Query: 68 XXXXXXXXXXXXXXXXXLENLRGGPNIITLADIVKDPVSRT-PALVFEHVNNTDFKQL-- 124
+ + + L D V+ T A+VFE + K +
Sbjct: 441 ETALDEVKLLKCVRESDVADPARAKCVQLLDDFKISGVNGTHVAMVFEVLGYNLLKLIIR 620
Query: 125 --YQTLTDYDIRFYMYEILKALDYCHSMG-IMHRDVKPHNVMI 164
YQ + ++++ + ++L+ L Y H+ I+H D+KP N++I
Sbjct: 621 SNYQGIPIHNVKLIIRQVLEGLSYMHAKCRIIHTDIKPENILI 749
>00392
Length = 668
Score = 38.9 bits (89), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 25/93 (26%), Positives = 51/93 (54%), Gaps = 3/93 (3%)
Frame = +3
Query: 133 IRFYMYEILKALDYCHSMG--IMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNV 190
++ + ++LK L + H+ ++HRD+K N+ I +++ D GLA + +V
Sbjct: 252 LKNWCRQVLKGLYFLHTRTPPVIHRDLKCDNIFITGPTGSVKIGDLGLATLKNQSFAKSV 431
Query: 191 RVASRYFKGPELLVDYQMYDYSLDMWSLG-CML 222
+ + F PE+ ++ YD ++D+++ G CML
Sbjct: 432 -IGTPEFMAPEMYEEH--YDEAVDVYAFGMCML 521
>26009
Length = 886
Score = 38.5 bits (88), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 14/33 (42%), Positives = 24/33 (72%)
Frame = +3
Query: 132 DIRFYMYEILKALDYCHSMGIMHRDVKPHNVMI 164
+ + M +++ ALD+ HS ++HRD+KP NV+I
Sbjct: 714 EAKSVMKQLVSALDFMHSKQLVHRDIKPENVLI 812
>05084
Length = 1324
Score = 38.5 bits (88), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 26/92 (28%), Positives = 40/92 (43%), Gaps = 2/92 (2%)
Frame = +2
Query: 235 GHDNYDQLVRIAKVLGTEDLYDYIDKYNI-ELDPRFNDI-LGRHSRKRWERFVHSENQHL 292
G DQLV I KVLGT + I E++P +++ + W +
Sbjct: 8 GDSGVDQLVEIIKVLGTP------TREQIREMNPNYSEFKFPQIKAHPWTKVFRPRTP-- 163
Query: 293 VSPEALDFLDKLLRYDHQSRLTAREAMEHPYF 324
PEA+ + +LL Y +R+ EA H +F
Sbjct: 164 --PEAIQLVSRLLEYTPSARIQPMEACAHAFF 253
>06358
Length = 1517
Score = 38.1 bits (87), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 48/176 (27%), Positives = 84/176 (47%), Gaps = 31/176 (17%)
Frame = +3
Query: 123 QLYQTLTDYDIRFYMYEILKALDYCHS-MGIMHRDVKPHNVMIDHEHRKLRLIDWGLA-- 179
Q YQ L D +I+ + ++ +AL + H+ +MHR+V P +M+ +L W LA
Sbjct: 339 QDYQ-LYDVEIKHGLLQVTEALGFLHNDAKMMHRNVCPEAIMLT------KLGSWKLAGY 497
Query: 180 EFY------------HPGQEYNVRVASRY-----FKGPELLVDYQMYDYSLDMWSLGCML 222
EF +P E+ +A F PE ++ Q S DM+SLG ++
Sbjct: 498 EFCVRSSDPQSTDPSYPFYEWRSDIAPVTQPHLDFMAPEYVLTMQCGTGS-DMFSLGLLV 674
Query: 223 ASMIFRKEPFFHGH-------DNYDQL--VRIAKVLGT--EDLYDYIDKYNIELDP 267
S+ + +P F + N ++L +R++ +LG EDL D++ K + ++P
Sbjct: 675 YSVFAKGKPLFECNGELSAFKSNAEELRHMRVS-LLGVVPEDLRDHV-KLLLNIEP 836
>21800
Length = 855
Score = 37.0 bits (84), Expect = 0.013, Method: Compositional matrix adjust.
Identities = 20/68 (29%), Positives = 38/68 (55%), Gaps = 6/68 (8%)
Frame = +2
Query: 125 YQTLTDYDIRFYMYEILKALDYCHS-MGIMHRDVKPHNVMI---DHEHRKLRL--IDWGL 178
YQ + ++++ + ++L+ L+Y H+ I+H D+KP N++I D+ RKL + +W
Sbjct: 614 YQGIPVHNVKLIIRQVLEGLNYLHAKCNIIHTDIKPENILICVDDNYIRKLAVDAFEWQR 793
Query: 179 AEFYHPGQ 186
PG
Sbjct: 794 LGLKLPGS 817
>32359
Length = 928
Score = 28.5 bits (62), Expect(2) = 0.023, Method: Compositional matrix adjust.
Identities = 9/17 (52%), Positives = 14/17 (82%)
Frame = -3
Query: 151 GIMHRDVKPHNVMIDHE 167
G+ HRD+KP N+++D E
Sbjct: 65 GVCHRDIKPQNLLLDPE 15
Score = 26.6 bits (57), Expect(2) = 0.023, Method: Compositional matrix adjust.
Identities = 15/49 (30%), Positives = 26/49 (53%), Gaps = 6/49 (12%)
Frame = -1
Query: 111 LVFEHVNNTDFK------QLYQTLTDYDIRFYMYEILKALDYCHSMGIM 153
LV E+V T ++ + QT+ I+ YMY++ ++L Y HS +
Sbjct: 202 LVLEYVPETVYRVARHYSKSKQTIPILYIKLYMYQLFRSLAYIHSQACV 56
>27546
Length = 426
Score = 35.8 bits (81), Expect = 0.026, Method: Compositional matrix adjust.
Identities = 24/101 (23%), Positives = 47/101 (46%), Gaps = 11/101 (10%)
Frame = -1
Query: 92 PNIITLADIVKDPVSRTPAL-----------VFEHVNNTDFKQLYQTLTDYDIRFYMYEI 140
PNII + I++ R P + + H+ T + + + + +++
Sbjct: 300 PNIIQIHSILQ----RGPKIFIFMRYAEKGDMLSHIKKTG------PIDEAQTKVWFFQM 151
Query: 141 LKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEF 181
KAL Y HS I HRD+K N+++ + +++ D+G A +
Sbjct: 150 AKALQYLHSHDIAHRDLKCENILLS-KRLNVKIADFGFARY 31
>02638
Length = 1490
Score = 35.4 bits (80), Expect = 0.035, Method: Compositional matrix adjust.
Identities = 31/128 (24%), Positives = 52/128 (40%)
Frame = +1
Query: 197 FKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYD 256
F PE+L + Y + D+WS+GC++ M + P ++ HD + L I K+ +
Sbjct: 34 FMAPEVL-RGESYGRACDVWSVGCVMIEMCTCRPP-WNSHDISNHLALIFKIASS----- 192
Query: 257 YIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAR 316
+D I EN +SP D + + L D R +A+
Sbjct: 193 -VDPPPI-----------------------PEN---MSPPVRDLMLRCLEQDSDFRPSAK 291
Query: 317 EAMEHPYF 324
+ + HP F
Sbjct: 292 DLLMHPLF 315
>28157
Length = 400
Score = 35.0 bits (79), Expect = 0.045, Method: Compositional matrix adjust.
Identities = 29/105 (27%), Positives = 46/105 (43%), Gaps = 13/105 (12%)
Frame = +3
Query: 92 PNIITLADIVKD-PVSRTPALVFEHVNNTDFKQLYQTL---------TDYDIRFYMYEIL 141
PNI+ L +D PV LV E+ LY L T ++ +
Sbjct: 90 PNIVCLYGACRDHPV----CLVMEYAEGGS---LYNVLHGSGPQPQYTAAHAMNWLLQCA 248
Query: 142 KALDYCHSM---GIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYH 183
++Y H M ++HRD+KP N+++ KL++ D+G A H
Sbjct: 249 LGVEYLHGMKPKALIHRDLKPPNLLLIQCGTKLKICDFGTACDIH 383
>18481
Length = 437
Score = 34.3 bits (77), Expect = 0.088, Method: Compositional matrix adjust.
Identities = 19/51 (37%), Positives = 31/51 (60%), Gaps = 3/51 (5%)
Frame = -1
Query: 139 EILKALDYCHSMGIMHRDVKPHNVMID---HEHRKLRLIDWGLAEFYHPGQ 186
++L L++ H +HRD+KP N ++ H HR L +ID+GL++ Y Q
Sbjct: 173 QLLSRLEFIHQKCFIHRDLKPDNFLMGLGRHCHR-LYIIDFGLSKRYKDTQ 24
>29360
Length = 363
Score = 33.5 bits (75), Expect = 0.16, Method: Composition-based stats.
Identities = 21/66 (31%), Positives = 33/66 (50%), Gaps = 14/66 (21%)
Frame = +3
Query: 113 FEHVNNT--DFKQLYQTLTDY------------DIRFYMYEILKALDYCHSMGIMHRDVK 158
F+H N+T F+ L Q L D+ IR ++L AL +G++H D+K
Sbjct: 162 FQHKNHTCLVFEMLEQNLYDFLKQNKFQPLPLKYIRPITQQVLTALRKLKQLGLIHADLK 341
Query: 159 PHNVMI 164
P N+M+
Sbjct: 342 PENIML 359
>15931
Length = 447
Score = 33.1 bits (74), Expect = 0.17, Method: Compositional matrix adjust.
Identities = 12/29 (41%), Positives = 20/29 (68%)
Frame = +1
Query: 296 EALDFLDKLLRYDHQSRLTAREAMEHPYF 324
+ D +DK+L Y+ +R + R+AM HP+F
Sbjct: 70 QLFDLMDKMLSYEVSTRYSLRQAMRHPFF 156
>19301
Length = 712
Score = 33.1 bits (74), Expect = 0.17, Method: Compositional matrix adjust.
Identities = 27/105 (25%), Positives = 53/105 (50%), Gaps = 10/105 (9%)
Frame = +2
Query: 85 LENLR--GGPNIITLADIVKDPVSRTPA--LVFEHVNNTDFKQLYQTLTDYD------IR 134
+ NLR PNII+ + ++ P ++ E+ + QLY+ L D +
Sbjct: 422 IRNLRKLNHPNIISFKGVC----TQAPCYCIIMEYC---PYGQLYEVLRDGKEIPPALVL 580
Query: 135 FYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLA 179
+ +I ++Y HS I+HRD+K NV++ ++ +++ D+G +
Sbjct: 581 DWSKQIASGMNYLHSHKIIHRDLKSPNVLV-AKNDVVKISDFGTS 712
>29590
Length = 320
Score = 32.7 bits (73), Expect = 0.23, Method: Composition-based stats.
Identities = 18/58 (31%), Positives = 28/58 (48%)
Frame = +3
Query: 175 DWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPF 232
D G A + G++ + + + PE+L DY+ DMWSLG + M+ PF
Sbjct: 6 DLGFACLTNTGEDIRDIIGTPDYVAPEVL-DYEPLSIQTDMWSLGVLSYVMLTACSPF 176
>26909
Length = 394
Score = 32.7 bits (73), Expect = 0.24, Method: Compositional matrix adjust.
Identities = 29/109 (26%), Positives = 43/109 (39%), Gaps = 10/109 (9%)
Frame = +2
Query: 226 IFRKEPFFHGHD---------NYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRH 276
+ EP FH ++DQL RI V+G D+ D + + R
Sbjct: 14 LLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFPQEKDWEDIRRMPEHQQLTKDFKRS 193
Query: 277 SRKRWERFVHSENQHL-VSPEALDFLDKLLRYDHQSRLTAREAMEHPYF 324
S + E + +A L KLL D R+T+ +AM+ PYF
Sbjct: 194 SYVNCNLMKYMEKHKVKADSKAFHLLQKLLTMDPVKRITSEQAMKDPYF 340
>14104
Length = 573
Score = 32.7 bits (73), Expect = 0.26, Method: Compositional matrix adjust.
Identities = 11/32 (34%), Positives = 19/32 (59%)
Frame = +1
Query: 293 VSPEALDFLDKLLRYDHQSRLTAREAMEHPYF 324
+P+A+ F+ L+ D RLT + ++HPY
Sbjct: 88 AAPQAMSFMQSCLKMDPAERLTCHQLLQHPYM 183
>11801
Length = 743
Score = 32.0 bits (71), Expect = 0.41, Method: Compositional matrix adjust.
Identities = 26/93 (27%), Positives = 49/93 (52%), Gaps = 3/93 (3%)
Frame = -1
Query: 215 MWSLGCMLASMIFRKEPFFHGHDNYDQLVR---IAKVLGTEDLYDYIDKYNIELDPRFND 271
++S G L +++ +K P YDQL R +AKV+ + D++ I+LDP+++
Sbjct: 302 VFSGGTALRTLL-KKFPVTSSSIPYDQLQRRCSVAKVVSETSCCKFGDQF-IKLDPQYDY 129
Query: 272 ILGRHSRKRWERFVHSENQHLVSPEALDFLDKL 304
+ ++S + R+ QH+ +AL F D +
Sbjct: 128 RVAKYSYLQSYRYFDDHKQHIR--QALMFNDTI 36
>12672
Length = 773
Score = 31.6 bits (70), Expect = 0.52, Method: Compositional matrix adjust.
Identities = 23/92 (25%), Positives = 43/92 (46%), Gaps = 7/92 (7%)
Frame = +3
Query: 142 KALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPG-----QEYNVRVASRY 196
+ Y + G +HRD+K N+++D E+ ++ D+ G Q +V + +
Sbjct: 24 SGIQYLNDNGHVHRDIKTANILLDSEYTA-KVGDFATVVSAPSGEGKTVQNASVVIGTAA 200
Query: 197 FKGPELLVDYQMYDYS--LDMWSLGCMLASMI 226
+ PE + +D S LD +S G +L +I
Sbjct: 201 YLAPEAI----HFDVSTKLDSYSFGVVLLEVI 284
>27274
Length = 396
Score = 31.2 bits (69), Expect = 0.76, Method: Compositional matrix adjust.
Identities = 30/126 (23%), Positives = 50/126 (39%)
Frame = -1
Query: 199 GPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYI 258
G ELL Q + ++DMWSLG +L ++ PF Q+ R +
Sbjct: 381 GAELLRG-QQHGPTVDMWSLGILLHELLSGHVPF-EPERGSRQMARNMMAV--------- 235
Query: 259 DKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREA 318
+ I+ SR + +S DFL +L++ + RLT+++A
Sbjct: 234 ----------YAQIIRGSSRDVCDGLA-------LSTHGADFLRRLVQLEDTKRLTSQQA 106
Query: 319 MEHPYF 324
HP+
Sbjct: 105 FSHPWI 88
>35032
Length = 465
Score = 30.4 bits (67), Expect = 1.3, Method: Compositional matrix adjust.
Identities = 12/27 (44%), Positives = 16/27 (59%)
Frame = +3
Query: 299 DFLDKLLRYDHQSRLTAREAMEHPYFY 325
D + +LL YD RLT A+ HP+ Y
Sbjct: 147 DLVKRLLNYDPSKRLTPXXALAHPFLY 227
>37063
Length = 455
Score = 30.0 bits (66), Expect = 1.5, Method: Compositional matrix adjust.
Identities = 23/78 (29%), Positives = 36/78 (46%), Gaps = 12/78 (15%)
Frame = -2
Query: 157 VKPHNVMIDH--EHRKLRLIDWGLAEFYHPGQ------EYNVRVASRYFKGPELLVDYQ- 207
+KP N++ +H E L++ D+ LA + E V S + PE++ +
Sbjct: 454 LKPENILCEHLDEVVPLKICDFDLASGINCDGDGTKTPELLTPVGSAEYMAPEVVDAWVG 275
Query: 208 ---MYDYSLDMWSLGCML 222
YD DMWSLG +L
Sbjct: 274 ESFSYDKRCDMWSLGIIL 221
>16350
Length = 1108
Score = 30.0 bits (66), Expect = 1.6, Method: Compositional matrix adjust.
Identities = 10/26 (38%), Positives = 18/26 (69%)
Frame = +3
Query: 299 DFLDKLLRYDHQSRLTAREAMEHPYF 324
DFL +L +D + R TA ++++HP+
Sbjct: 762 DFLAPMLEFDPEQRATAAQSLQHPWL 839
>17932
Length = 597
Score = 29.6 bits (65), Expect = 2.2, Method: Compositional matrix adjust.
Identities = 17/35 (48%), Positives = 22/35 (62%)
Frame = -3
Query: 293 VSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTV 327
VS EA D + +LL D +SRL E +HP+F TV
Sbjct: 460 VSKEARDLISQLLS-DGKSRLGWPELQQHPFFKTV 359
>20513
Length = 405
Score = 29.3 bits (64), Expect = 2.7, Method: Compositional matrix adjust.
Identities = 10/26 (38%), Positives = 18/26 (69%)
Frame = -1
Query: 299 DFLDKLLRYDHQSRLTAREAMEHPYF 324
DFL +L +D + R TA ++++HP+
Sbjct: 282 DFLAPMLEFDPEQRATAAQSLQHPWL 205
>18663
Length = 600
Score = 28.9 bits (63), Expect = 3.8, Method: Compositional matrix adjust.
Identities = 13/34 (38%), Positives = 21/34 (61%)
Frame = +2
Query: 199 GPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPF 232
PE+L + Y +S+D W+LG +L M+ + PF
Sbjct: 32 APEILRG-EDYGFSVDWWALGVLLYEMLAGRSPF 130
>20773
Length = 391
Score = 28.5 bits (62), Expect = 4.8, Method: Compositional matrix adjust.
Identities = 16/50 (32%), Positives = 25/50 (50%)
Frame = -1
Query: 274 GRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPY 323
G H R+ F H+ +V+ + + +LL YD RLT A+ HP+
Sbjct: 370 GLHRRRSRPVFPHTT---VVTQHFYNLVQRLLTYDPSQRLTPDLALSHPF 230
>20152
Length = 445
Score = 28.1 bits (61), Expect = 5.6, Method: Compositional matrix adjust.
Identities = 12/39 (30%), Positives = 23/39 (58%)
Frame = +1
Query: 200 PELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDN 238
PE+L+ ++D+WSLG +L ++ + PF +D+
Sbjct: 1 PEILLGDSYDAPAVDVWSLGVILYMLVVGEAPFQEANDS 117
>28419
Length = 687
Score = 28.1 bits (61), Expect = 6.8, Method: Compositional matrix adjust.
Identities = 26/96 (27%), Positives = 43/96 (44%), Gaps = 5/96 (5%)
Frame = +3
Query: 140 ILKALDYCHSMG----IMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASR 195
ILK L YC ++ ++ K N+ EH K++ + G + +R S+
Sbjct: 342 ILKRLRYCLNLSKPPSYLNTVRKL*NISYVREHDKVKALMLGFKLLVNSQCANALRHPSQ 521
Query: 196 YFKGPELL-VDYQMYDYSLDMWSLGCMLASMIFRKE 230
KGPEL+ D+Q Y++ C+ + RKE
Sbjct: 522 I*KGPELIPYDFQFYEF-----PTACVTSPY*VRKE 614
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000227378 | hsapiens_gene_ensembl | Heat shock
cognate 71 kDa protein (Heat shock 70 kDa protein 8).
[Source:Uniprot/SWISSPROT;Acc:P11142]
(646 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
30255 295 e-111
21024 224 8e-59
37715 152 3e-56
27378 199 2e-51
26390 168 6e-42
24750 141 1e-33
06909 99 8e-26
31218 95 7e-20
09881 89 6e-18
20979 84 3e-16
12271 62 5e-10
13684 56 4e-08
03996 51 2e-06
34036 48 1e-05
13300 46 6e-05
>30255
Length = 1761
Score = 295 bits (756), Expect(2) = e-111, Method: Compositional matrix adjust.
Identities = 150/199 (75%), Positives = 155/199 (77%)
Frame = -1
Query: 328 KSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELNKSINPDEXXXXXXXXXXXILSGDKSEN 387
K IH+IVLVGGSTRIPKIQKLLQDFFNGKEL KSINPDE IL GDKSE
Sbjct: 1644 KPGIHEIVLVGGSTRIPKIQKLLQDFFNGKELCKSINPDEAVAYGACVQAAILHGDKSEE 1465
Query: 388 VQDXXXXXXXXXXXGIETAGGVMTVLIKRNXXXXXXXXXXXXXYSDNQPGVLIQVYEGER 447
VQD GIETAGGVMT LIKRN YSDNQPGVLIQVYEGER
Sbjct: 1464 VQDLLLLDVAPLSMGIETAGGVMTALIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGER 1285
Query: 448 AMTKDNNLLGKFELTGIPPAPRGVPQIEVTFDIDANGILNVSAVDKSTGKENKITITNDK 507
AMT+DNNLLGKFELTGIPPAPRGVPQIEVTFDIDANGILNVSA DKSTGKENKITITNDK
Sbjct: 1284 AMTRDNNLLGKFELTGIPPAPRGVPQIEVTFDIDANGILNVSAADKSTGKENKITITNDK 1105
Query: 508 GRLSKEDIERMVQEAEKYK 526
GRLSKE+IERMV +AEK +
Sbjct: 1104 GRLSKEEIERMVNDAEKSR 1048
Score = 127 bits (318), Expect(2) = e-111, Method: Compositional matrix adjust.
Identities = 57/79 (72%), Positives = 74/79 (93%)
Frame = -3
Query: 534 DKVSSKNSLESYAFNMKATVEDEKLQGKINDEDKQKILDKCNEIINWLDKNQTAEKEEFE 593
+++SSKNSLESYAF+MK+T+EDEK++ KI +EDK+ I+DKCNE+I+WLD NQTAEK+E++
Sbjct: 1027 NRISSKNSLESYAFHMKSTIEDEKIKDKIGEEDKKTIVDKCNEVISWLDANQTAEKDEYD 848
Query: 594 HQQKELEKVCNPIITKLYQ 612
+QKELEKVCNPIITKLYQ
Sbjct: 847 DKQKELEKVCNPIITKLYQ 791
>21024
Length = 3220
Score = 224 bits (571), Expect = 8e-59, Method: Compositional matrix adjust.
Identities = 167/457 (36%), Positives = 242/457 (52%), Gaps = 22/457 (4%)
Frame = +1
Query: 166 GLNVLRIINEPTAAAIA--YGL-----DKKVGAER----NVLIFDLGGGTFDVSILTIED 214
G NVLR+INEPTAAA+A +G D V R ++ + D G ++
Sbjct: 727 G*NVLRVINEPTAAALALWHGQV*R*SDSGV*FRRRDV*HLYLGDPEG--------SV*S 882
Query: 215 GIFEVKSTAGDTHLGGEDFDNRMVNHFIAEFKRKHKKDISENKRAVRRLRTACERAKRTL 274
I + + G L + + RK K S+ + + R +++K L
Sbjct: 883 QINQRRHIPGRRGLLTTTWSTSWHQNL-----RKSKD*TSQRIQWLCRDYVRQQKSKIEL 1047
Query: 275 SSSTQASIEIDSLYEGID------FYTSITRARFEELNADLFRGTLDPVEKALRDAKLDK 328
SSS Q I + Y +D ++R++FE L L + T+ P +KAL+DA++ K
Sbjct: 1048 SSSLQTDINLP--YLTMDASGPKHMNLKLSRSKFESLVESLVKRTVGPCQKALQDAEVKK 1221
Query: 329 SQIHDIVLVGGSTRIPKIQKLLQDFFNGKELNKSINPDEXXXXXXXXXXXILSGDKSENV 388
S I +++LVGG +R+PK+Q +QD F G+ +KS+NPDE +L+GD V
Sbjct: 1222 SDIGEVILVGGMSRMPKVQSTVQDLF-GRTPSKSVNPDEAVAIGAAIQGGVLAGD----V 1386
Query: 389 QDXXXXXXXXXXXGIETAGGVMTVLIKRNXXXXXXXXXXXXXYSDNQPGVLIQVYEGERA 448
D GIET GGV T LI RN +D Q V I+V++GER
Sbjct: 1387 TDVLLLDVTPLSLGIETLGGVFTKLINRNTTIPTKKSQVFSTAADGQTQVEIKVHQGERE 1566
Query: 449 MTKDNNLLGKFELTGIPPAPRGVPQIEVTFDIDANGILNVSAVDKSTGKENKITITNDKG 508
M DN LLG+F L GIPPAPRGVPQ+EVTFDIDANGI+NVSA DK TGKE +I I + G
Sbjct: 1567 MANDNKLLGQFTLVGIPPAPRGVPQVEVTFDIDANGIVNVSARDKGTGKEQQIVIQSSGG 1746
Query: 509 RLSKEDIERMVQEAEKYKAEDEKQRDKVSSKNSLESYAFNMKATVEDEKLQGKINDEDKQ 568
LSK++IE M++ AE + +D ++++ V N +S + ++ +E+ K Q + E+
Sbjct: 1747 -LSKDEIENMIKNAEAHAEDDRRKKELVEVLNQADSIIHDTESKMEEFKDQ--LPQEECD 1917
Query: 569 KILDKCNEIINWL--DKNQTAEK---EEFEHQQKELE 600
K+ +K NE+ L N+ EK E + QQK L+
Sbjct: 1918 KLREKINEVKQLLANKDNEAPEKIREETSDLQQKSLK 2028
Score = 188 bits (477), Expect = 7e-48, Method: Compositional matrix adjust.
Identities = 115/269 (42%), Positives = 158/269 (58%), Gaps = 2/269 (0%)
Frame = +3
Query: 3 KGPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQVAM 61
KG +GIDLGTT SCV + + + +++ N +G+RTTPS +AFT D ER+ G AK Q
Sbjct: 243 KGHVIGIDLGTTNSCVALMEGKQAKVLENSEGSRTTPSVIAFTKDGERISGMPAKRQAVT 422
Query: 62 NPTNTVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPEEVSS 121
N NT+ KRLIGRRF+D VQ DMK+ + +V A VE +G K + P +V +
Sbjct: 423 NAENTLSATKRLIGRRFEDPEVQKDMKNVSYKIVK-ASNGDAWVEAQG--KMYSPSQVGA 593
Query: 122 MVLTKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAI 181
VL KMKE AE+YLG V NAVVTVPAYFNDSQRQATKDAG I+GL + + +
Sbjct: 594 FVLMKMKETAESYLGSKVNNAVVTVPAYFNDSQRQATKDAGQISGLKCVACDQRTHSCSS 773
Query: 182 AYGLDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGE-DFDNRMVNH 240
+ + + + G +S + + + + T +TH E FDN MVN
Sbjct: 774 CFMAWTSLKIK**RCLI*AEGRLTSLSWRSRRECLKSNQPT--ETHSWEERTFDNYMVNF 947
Query: 241 FIAEFKRKHKKDISENKRAVRRLRTACER 269
+EFK++ DI+++ AV+RLR A E+
Sbjct: 948 LASEFKKEQGLDITKDPMAVQRLREAAEK 1034
>37715
Length = 468
Score = 152 bits (384), Expect(2) = 3e-56, Method: Compositional matrix adjust.
Identities = 71/97 (73%), Positives = 84/97 (86%)
Frame = -2
Query: 94 VVNDAGRPKVQVEYKGETKSFYPEEVSSMVLTKMKEIAEAYLGKTVTNAVVTVPAYFNDS 153
V+N + +P +Q G TK+F PEE+S+MVL KM++IAEAYLGK + NAVVTVPAYFND+
Sbjct: 452 VINKSNKPHIQALVSGATKTFAPEEISAMVLGKMRDIAEAYLGKKIDNAVVTVPAYFNDA 273
Query: 154 QRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKVG 190
QRQATKDAGTIAGLNV+RIINEPTAAAIAYGLDK+ G
Sbjct: 272 QRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKRDG 162
Score = 85.5 bits (210), Expect(2) = 3e-56, Method: Composition-based stats.
Identities = 36/49 (73%), Positives = 46/49 (93%)
Frame = -1
Query: 194 NVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNHFI 242
N+L+FDLGGGTFDVS+LTI++G+FEV +T GDTHLGGEDFD R+++HFI
Sbjct: 156 NILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMDHFI 10
>27378
Length = 410
Score = 199 bits (507), Expect = 2e-51, Method: Compositional matrix adjust.
Identities = 96/124 (77%), Positives = 107/124 (86%)
Frame = -1
Query: 244 EFKRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITRARFE 303
EFKRK+KKD+ N RA+RRLRTA ERAKRTLSSST+A+IE+D+L+EG DFYT I+RARFE
Sbjct: 410 EFKRKYKKDLRSNPRALRRLRTAAERAKRTLSSSTEATIEVDALFEGHDFYTKISRARFE 231
Query: 304 ELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELNKSI 363
EL ADLFR TL PVEKAL DAK+DK IHDIVLVGGSTRIPK+Q LLQ FF GK LN SI
Sbjct: 230 ELCADLFRQTLAPVEKALNDAKMDKQMIHDIVLVGGSTRIPKVQNLLQQFFGGKSLNLSI 51
Query: 364 NPDE 367
NPDE
Sbjct: 50 NPDE 39
>26390
Length = 665
Score = 168 bits (426), Expect = 6e-42, Method: Compositional matrix adjust.
Identities = 84/154 (54%), Positives = 102/154 (66%)
Frame = +2
Query: 402 GIETAGGVMTVLIKRNXXXXXXXXXXXXXYSDNQPGVLIQVYEGERAMTKDNNLLGKFEL 461
GIET GGVMT LI R DNQ V IQVYEGER+ TKDN+LLG+F+L
Sbjct: 50 GIETVGGVMTTLIARGTTIPARKAKVFSTAQDNQDSVTIQVYEGERSRTKDNHLLGRFDL 229
Query: 462 TGIPPAPRGVPQIEVTFDIDANGILNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQE 521
TGIP APRGVPQIEVTF +DANG++ VSA DK TG++N I I LS ED+ERMVQE
Sbjct: 230 TGIPAAPRGVPQIEVTFQVDANGVMQVSAEDKGTGQKNDIIIQQSGSGLSPEDVERMVQE 409
Query: 522 AEKYKAEDEKQRDKVSSKNSLESYAFNMKATVED 555
A+ + ED K R+ S+ LES A+ + ++D
Sbjct: 410 AQDFAEEDRKFRELTESRTGLESLAYTAQHQLQD 511
>24750
Length = 552
Score = 141 bits (355), Expect = 1e-33, Method: Compositional matrix adjust.
Identities = 66/71 (92%), Positives = 70/71 (98%)
Frame = +1
Query: 439 LIQVYEGERAMTKDNNLLGKFELTGIPPAPRGVPQIEVTFDIDANGILNVSAVDKSTGKE 498
++QVYEGERAMT+DNNLLGKFELTGIPPAPRGVPQIEVTFDIDANGILNVSA DKSTGKE
Sbjct: 154 MLQVYEGERAMTRDNNLLGKFELTGIPPAPRGVPQIEVTFDIDANGILNVSAADKSTGKE 333
Query: 499 NKITITNDKGR 509
NKITITNDKG+
Sbjct: 334 NKITITNDKGQ 366
>06909
Length = 456
Score = 99.4 bits (246), Expect(2) = 8e-26, Method: Compositional matrix adjust.
Identities = 44/66 (66%), Positives = 58/66 (87%)
Frame = -3
Query: 547 FNMKATVEDEKLQGKINDEDKQKILDKCNEIINWLDKNQTAEKEEFEHQQKELEKVCNPI 606
+MK+T+EDEK++ KI+ EDK+ ILDKC+E+I WLD NQ AEK+E++ +QKE+EKVCNPI
Sbjct: 388 LHMKSTIEDEKIKDKISTEDKKTILDKCDEVIAWLDANQLAEKDEYDDKQKEIEKVCNPI 209
Query: 607 ITKLYQ 612
ITKLYQ
Sbjct: 208 ITKLYQ 191
Score = 36.6 bits (83), Expect(2) = 8e-26, Method: Compositional matrix adjust.
Identities = 16/23 (69%), Positives = 21/23 (91%)
Frame = -1
Query: 524 KYKAEDEKQRDKVSSKNSLESYA 546
KYK +DEKQ+ ++S+KNSLESYA
Sbjct: 456 KYKEDDEKQKSRISAKNSLESYA 388
>31218
Length = 322
Score = 95.1 bits (235), Expect = 7e-20, Method: Compositional matrix adjust.
Identities = 47/100 (47%), Positives = 68/100 (68%)
Frame = +2
Query: 225 DTHLGGEDFDNRMVNHFIAEFKRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEI 284
DTHLGGEDFD R+V++ + K+K +D+ + RA+ RLR + E+AKR LSS +++
Sbjct: 2 DTHLGGEDFDQRLVDYLVKLIKQKTGRDVRHDTRAMSRLRRSAEKAKRALSSQHSTKVDL 181
Query: 285 DSLYEGIDFYTSITRARFEELNADLFRGTLDPVEKALRDA 324
D + + T +TRA+FEELN DLFR TL V++AL D+
Sbjct: 182 DGVTSDLADLT-LTRAKFEELNTDLFRSTLTTVKRALEDS 298
>09881
Length = 600
Score = 88.6 bits (218), Expect = 6e-18, Method: Composition-based stats.
Identities = 44/109 (40%), Positives = 64/109 (58%)
Frame = +3
Query: 3 KGPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMN 62
K A G+ LGT +C+ V++ GK + AND G+R+TP VAFT + +G +AK + N
Sbjct: 177 KMAAYGVHLGTCSACLAVYKDGKTSVAANDAGDRSTPCVVAFTACDAEVGASAKQGIVSN 356
Query: 63 PTNTVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGET 111
NTV + KR++G F+D V Q + P VVN +P +VE+K T
Sbjct: 357 VKNTVCNVKRILGLTFEDPVTQEYLASSPVKVVNQKNQPMFEVEFKERT 503
Score = 49.7 bits (117), Expect = 3e-06, Method: Composition-based stats.
Identities = 27/54 (50%), Positives = 37/54 (68%)
Frame = +2
Query: 136 GKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKV 189
GK + +AV+ VP+ F+D QR A A + AG VLR+INE +AAA+AY L + V
Sbjct: 2 GKGIQDAVLAVPSDFSDKQRAAASAAASKAGFKVLRLINECSAAALAYDLGQTV 163
>20979
Length = 976
Score = 83.6 bits (205), Expect = 3e-16, Method: Compositional matrix adjust.
Identities = 45/140 (32%), Positives = 79/140 (56%), Gaps = 2/140 (1%)
Frame = +1
Query: 230 GEDFDNRMVNHFIAEFKRKHKKD--ISENKRAVRRLRTACERAKRTLSSSTQASIEIDSL 287
G + R+ +H F + K+ + +N RA+ +L ER K+ LS+++ +++ L
Sbjct: 70 GVEMTLRLRDHLAKVFNGQKKRSFKLEDNPRAMAKLLKEAERVKKVLSANSDHKAQVEGL 249
Query: 288 YEGIDFYTSITRARFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQ 347
EG DF ++R + EL DL P+E AL+ +++ +I +I+L+GG +R+P++Q
Sbjct: 250 VEGEDFAAKVSREDYLELIKDLLARVTKPMEDALKVSEITMPEITEIILMGGGSRVPRVQ 429
Query: 348 KLLQDFFNGKELNKSINPDE 367
+ L F +L KSIN DE
Sbjct: 430 EELLKFSGKSDLGKSINTDE 489
>12271
Length = 1762
Score = 62.4 bits (150), Expect = 5e-10, Method: Compositional matrix adjust.
Identities = 29/76 (38%), Positives = 48/76 (63%)
Frame = +2
Query: 292 DFYTSITRARFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQ 351
DF +TR ++ L DL PV++ L +++ ++I +I+L+GG +R+PKI ++L
Sbjct: 41 DFSCKVTRDKYLHLIQDLLDRVTLPVQQVLTASQITWAEITEIILMGGGSRLPKIHEILL 220
Query: 352 DFFNGKELNKSINPDE 367
D+ KEL KS+N DE
Sbjct: 221 DYSGKKELGKSLNTDE 268
Score = 33.5 bits (75), Expect = 0.26, Method: Compositional matrix adjust.
Identities = 26/121 (21%), Positives = 53/121 (43%), Gaps = 3/121 (2%)
Frame = +1
Query: 487 NVSAVDKSTGKENKITIT---NDKGRLSKEDIERMVQEAEKYKAEDEKQRDKVSSKNSLE 543
N A G K+ +T D LSK+ +++ + ++ DE++ ++N +E
Sbjct: 937 NKKAASAGKGFNEKLKVTVKVKDMAELSKDQVKQSKKRLTDWRKRDEEKAAVQKARNEVE 1116
Query: 544 SYAFNMKATVEDEKLQGKINDEDKQKILDKCNEIINWLDKNQTAEKEEFEHQQKELEKVC 603
S+ + + +E DE++ ILD+ ++ +WL + K+ F E C
Sbjct: 1117 SFIITAQDKMSEETYLASSTDEERAXILDQLSQASDWLYEQSHQAKKWFSPTNTET*GTC 1296
Query: 604 N 604
+
Sbjct: 1297 S 1299
>13684
Length = 438
Score = 56.2 bits (134), Expect = 4e-08, Method: Composition-based stats.
Identities = 25/60 (41%), Positives = 37/60 (61%)
Frame = -3
Query: 3 KGPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMN 62
K A G+ LGT +C+ V++ GK + AND G+R+TP VAFT + +G +AK + N
Sbjct: 181 KMAAYGVHLGTCSACLAVYKDGKTSVAANDAGDRSTPCVVAFTACDAEVGASAKQGIVSN 2
>03996
Length = 1105
Score = 50.8 bits (120), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 25/64 (39%), Positives = 40/64 (62%)
Frame = -2
Query: 304 ELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELNKSI 363
EL DL P+E AL+ +++ +I +I+L+GG +R+P++Q+ L F +L KSI
Sbjct: 1056 ELIKDLLARVTKPMEDALKVSEITMPEITEIILMGGGSRVPRVQEELLKFSGKSDLGKSI 877
Query: 364 NPDE 367
N DE
Sbjct: 876 NTDE 865
>34036
Length = 363
Score = 48.1 bits (113), Expect = 1e-05, Method: Composition-based stats.
Identities = 19/25 (76%), Positives = 24/25 (96%)
Frame = +2
Query: 588 EKEEFEHQQKELEKVCNPIITKLYQ 612
EK+E++ +QKE+EKVCNPIITKLYQ
Sbjct: 2 EKDEYDDKQKEIEKVCNPIITKLYQ 76
>13300
Length = 453
Score = 45.8 bits (107), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 32/149 (21%), Positives = 72/149 (48%), Gaps = 17/149 (11%)
Frame = +3
Query: 154 QRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKVG---AERNVLIFDLGGGTFDVSIL 210
+R+A A G+NVL+++ + A A+ YG+ ++ + + +D+G + +++
Sbjct: 3 ERRAIMTAADXVGINVLQLMTDSAAVALNYGVFRRKNFNTTAQYYMFYDMGATSTVATVV 182
Query: 211 T-----IEDGI-------FEVKSTAGDTHLGGEDFDNRMVNHFIAEFKRKHKKD--ISEN 256
+ +++G +K D LGG + R+ +H F + K+ + +N
Sbjct: 183 SYQVVKVKEGTRVESNPQLTIKGVGFDRTLGGLEMTLRLRDHLAKVFNGQKKRSFKLEDN 362
Query: 257 KRAVRRLRTACERAKRTLSSSTQASIEID 285
RA+ +L ER K+ LS+++ +++
Sbjct: 363 PRAMAKLLKEAERVKKVLSANSDHKAQVE 449
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000343995 | hsapiens_gene_ensembl | Tektin-3.
[Source:Uniprot/SWISSPROT;Acc:Q9BXF9]
(490 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
03948 397 e-111
16615 347 8e-96
14949 180 1e-45
33456 134 7e-32
35150 118 5e-27
36475 67 2e-11
31693 62 5e-10
>03948
Length = 2007
Score = 397 bits (1020), Expect = e-111, Method: Compositional matrix adjust.
Identities = 198/393 (50%), Positives = 268/393 (68%)
Frame = +1
Query: 89 TFFTRYTPDDWYRSNLTNYQESNTSRHNSEKLRVDTSRLIQDKYQQTRKTQADTTQNLGE 148
+ ++RY+P+DW SN NY S+ R +E+LR D R +++ +TR Q D T+ LGE
Sbjct: 16 SVYSRYSPNDWNLSNSMNYSLSDKERSFAERLRADAWRAVKETDARTRNRQNDVTKRLGE 195
Query: 149 RVNDIGFWKSEIIHELDEMIGETNALTDVKKRLERALMETEAPLQVARECLFHREKRMGI 208
RV DI FWK+E+ E++ M E L + K+ E+AL +T PL +A ECL +REKR GI
Sbjct: 196 RVYDIXFWKTELNSEVNAMATEIENLKEYKRTCEKALADTANPLHIAEECLMNREKRQGI 375
Query: 209 DLVHDEVEAQLLTEVDTILCCQERMKLHLDKAIAQLAANRASQHELEKDLSDKQTAYRID 268
DLV+D+VE L+ EVD I CQ RMK LDKA QL NRA+QH LE D DK A +D
Sbjct: 376 DLVNDDVEKSLVKEVDIIKRCQARMKKVLDKAYVQLKMNRAAQHALEIDAKDKHHAQGLD 555
Query: 269 DKCHHLRNTSDGVGYFRGVERVDATVSVPESWAKFTDDNILRSQSERAASAKLRDDIENL 328
D+ +RN+S GVGY G+E +D T+++PESWA++T +NI RSQ ERA+S +LR +I++
Sbjct: 556 DRMQQMRNSSAGVGYIPGIESIDNTLTIPESWARYTQENIARSQKERASSERLRGEIDST 735
Query: 329 LVVTANEMWNQFNKVNLSFTNRIAETADAKNKIQTHLAKTLQEIFQTEMTIESIKKAIKD 388
L ANEMWN FN VN SF R+ ET DA+NK+Q HL +T+QEIF E I ++KAI+D
Sbjct: 736 LRHCANEMWNNFNAVNNSFNTRVRETTDARNKLQAHLQRTMQEIFDMERNINLLRKAIQD 915
Query: 389 KTAFLKVAQTRLDERTRRPNIELCRDMAQLRLVNEVHEVDDTIQTLQQRLRDAEDTLQSL 448
K +KVAQTRLDERTRR N+ELC D L EV E+ ++++ L++RL+ +E +L L
Sbjct: 916 KENPMKVAQTRLDERTRRINVELCNDPVMKSLQREVAEIRESVRLLKERLKSSELSLARL 1095
Query: 449 VHIKATLEYDLAVKANSLYIDQEKCMSMRKSYP 481
+ K+TLE+D++VK NSL ID CM MRK +P
Sbjct: 1096MKTKSTLEHDISVKENSLRIDNSFCMGMRKGFP 1194
>16615
Length = 1307
Score = 347 bits (889), Expect = 8e-96, Method: Compositional matrix adjust.
Identities = 194/422 (45%), Positives = 267/422 (63%), Gaps = 28/422 (6%)
Frame = -3
Query: 52 PSTYYKVAS-NSPSVAPYCTRSQRVSE-NTMLPFVSNRT--------------------- 88
PS +++A +SPSV + + E + +LP+V+++T
Sbjct: 1272 PSDNFRMAYYDSPSVVRTRSATPMTPEMSKILPYVTDKTISRHLGSYGKSMDLGHARNYF 1093
Query: 89 -----TFFTRYTPDDWYRSNLTNYQESNTSRHNSEKLRVDTSRLIQDKYQQTRKTQADTT 143
T ++RY P+DW SN NY S+ R +E+LR D R +++ +TR Q D T
Sbjct: 1092 NPAMRTVYSRYNPNDWSLSNSMNYSLSDKERSFAERLRADAWRAVKETDARTRNRQNDVT 913
Query: 144 QNLGERVNDIGFWKSEIIHELDEMIGETNALTDVKKRLERALMETEAPLQVARECLFHRE 203
+ LGERV DI FWK+E+ E++ M E L + K+ E+AL +T PL +A ECL HRE
Sbjct: 912 KRLGERVYDISFWKTELNSEVNAMATEIENLKEYKRTCEKALADTANPLHIAEECLMHRE 733
Query: 204 KRMGIDLVHDEVEAQLLTEVDTILCCQERMKLHLDKAIAQLAANRASQHELEKDLSDKQT 263
KR GIDLV+D+VE L+ EVD I CQ +MK LDKA QL NRA+QH LE D DK
Sbjct: 732 KRQGIDLVNDDVEKSLVKEVDVIKKCQAKMKKVLDKAYVQLKMNRAAQHALEIDAKDKHH 553
Query: 264 AYRIDDKCHHLRNTSDGVGYFRGVERVDATVSVPESWAKFTDDNILRSQSERAASAKLRD 323
A +DD+ LRN+S GVGY G+E +D T+++PESWA++T +NI RSQ ERAAS +LR
Sbjct: 552 AQGLDDRMQQLRNSSAGVGYIPGIENIDNTLTIPESWARYTQENIARSQKERAASERLRG 373
Query: 324 DIENLLVVTANEMWNQFNKVNLSFTNRIAETADAKNKIQTHLAKTLQEIFQTEMTIESIK 383
+I++ L ANEMWN FN VN +F RI E+ DA+NK+Q HL KT+QEIF E I+ ++
Sbjct: 372 EIDSTLRQCANEMWNNFNAVNNAFNTRIRESNDARNKLQAHLQKTMQEIFDMERNIDLLR 193
Query: 384 KAIKDKTAFLKVAQTRLDERTRRPNIELCRDMAQLRLVNEVHEVDDTIQTLQQRLRDAED 443
KAI+DK +KVAQTRLDERTRR N+ELC D L EV E+ ++++ L++RL+ +E
Sbjct: 192 KAIQDKENPMKVAQTRLDERTRRINVELCNDPVMKSLQREVAEIRESVRLLKERLKSSEL 13
Query: 444 TL 445
+L
Sbjct: 12 SL 7
>14949
Length = 465
Score = 180 bits (457), Expect = 1e-45, Method: Compositional matrix adjust.
Identities = 82/151 (54%), Positives = 112/151 (74%)
Frame = -3
Query: 237 LDKAIAQLAANRASQHELEKDLSDKQTAYRIDDKCHHLRNTSDGVGYFRGVERVDATVSV 296
++KA QL RA+QHELEKD DKQ A +D CH +RN+S G+ ++ GV R D TVSV
Sbjct: 454 IEKANVQLGLGRAAQHELEKDSIDKQIAESMDTSCHGIRNSSHGIAFYNGVYRTDNTVSV 275
Query: 297 PESWAKFTDDNILRSQSERAASAKLRDDIENLLVVTANEMWNQFNKVNLSFTNRIAETAD 356
PE+WA+F++DN+ RSQSERAAS ++R++IE +L +NEMWNQ+N N++ RI ET D
Sbjct: 274 PETWARFSNDNVQRSQSERAASKQMRNEIETVLNACSNEMWNQWNAANVALNQRIQETTD 95
Query: 357 AKNKIQTHLAKTLQEIFQTEMTIESIKKAIK 387
+N++QTHL+K LQEIF E IE +KK+I+
Sbjct: 94 TRNRLQTHLSKVLQEIFDMEKNIELLKKSIQ 2
>33456
Length = 677
Score = 134 bits (338), Expect = 7e-32, Method: Compositional matrix adjust.
Identities = 76/202 (37%), Positives = 116/202 (57%), Gaps = 6/202 (2%)
Frame = +3
Query: 93 RYTPDDWYRSNLTNYQESNTSRHNSEKLRVDTSRLIQDKYQQTRKTQADTTQNLGERVND 152
+Y P +W+ SN + Y +S R +E++R ++ R + T KTQAD T+ L ER D
Sbjct: 66 KYNPSEWHESNYSKYYQSFVDRDQAERVRHESKRTSNETEATTNKTQADVTKKLAERCKD 245
Query: 153 IGFWKSEIIHELDEMIGETNALTDVKKRLERALMETEAPLQVARECLFHREKRMGIDLVH 212
I FWK+E+ E+ ++I ET+ L KKRLE AL TE PL ++ + L R++R+G+DLV
Sbjct: 246 IQFWKAEVEREIRDVIDETDLLLAQKKRLENALRATEVPLHISTDNLNCRQRRLGVDLVQ 425
Query: 213 DEVEAQLLTEVDTILCCQERMKLHLDKAIAQLAANRASQHELEKDLSDKQTAYRIDDKCH 272
D+VE LL EV I ++ ++ + ++ Q+ NR ++ LE D SDK+ + ID C
Sbjct: 426 DDVEISLLKEVXIINNVRDLLQNTIAQSEKQIRLNRDAKQNLEMDWSDKKESLEIDTSCG 605
Query: 273 HLRNT------SDGVGYFRGVE 288
LRN DG F ++
Sbjct: 606 VLRNHHTNKQFHDGAAKFEEIQ 671
>35150
Length = 410
Score = 118 bits (296), Expect = 5e-27, Method: Compositional matrix adjust.
Identities = 59/124 (47%), Positives = 84/124 (67%)
Frame = +2
Query: 356 DAKNKIQTHLAKTLQEIFQTEMTIESIKKAIKDKTAFLKVAQTRLDERTRRPNIELCRDM 415
D K K++ HL K + +I + E I ++KAI DK A +K+A TRLD RT RPN+ELCRD
Sbjct: 5 DTKGKLEDHLNKIIGQIKEIEENISRLQKAIADKEAPMKLAHTRLDTRTNRPNVELCRDA 184
Query: 416 AQLRLVNEVHEVDDTIQTLQQRLRDAEDTLQSLVHIKATLEYDLAVKANSLYIDQEKCMS 475
Q R + EV E++ ++ LQ RL D +D+L+ L + LE D+ VK+N+L+ID+ +CM
Sbjct: 185 VQYRPIGEVGELECSLAQLQSRLADTQDSLKGLTRNQLDLEDDIQVKSNTLFIDEVECMG 364
Query: 476 MRKS 479
MRKS
Sbjct: 365 MRKS 376
>36475
Length = 841
Score = 67.0 bits (162), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 29/72 (40%), Positives = 53/72 (73%)
Frame = +3
Query: 418 LRLVNEVHEVDDTIQTLQQRLRDAEDTLQSLVHIKATLEYDLAVKANSLYIDQEKCMSMR 477
RLV EV+E+ +I L+ +L A+++L+ L + +LE +++VK NS++ID++KCM++R
Sbjct: 207 FRLVGEVNEICQSIDALKNQLNQAQNSLKDLQDNRMSLEKEISVKKNSIFIDRDKCMTVR 386
Query: 478 KSYPNTLRLVGF 489
YP+T++L G+
Sbjct: 387 TRYPSTVKLQGY 422
>31693
Length = 851
Score = 62.0 bits (149), Expect = 5e-10, Method: Compositional matrix adjust.
Identities = 29/54 (53%), Positives = 40/54 (74%)
Frame = -2
Query: 393 LKVAQTRLDERTRRPNIELCRDMAQLRLVNEVHEVDDTIQTLQQRLRDAEDTLQ 446
+KVAQTRL+ RT RPN+ELCRD Q LV EV+E+ +I L+ +L AE++L+
Sbjct: 604 MKVAQTRLNSRTYRPNVELCRDPVQYALVGEVNEICQSIDALKNQLNQAENSLK 443
Score = 54.3 bits (129), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 43/139 (30%), Positives = 64/139 (46%), Gaps = 13/139 (9%)
Frame = -1
Query: 364 HLAKTLQEIFQTEMTIESIKKAIK----------DKTAFLKVAQTR---LDERTRRPNIE 410
+L K EI Q E I+S+K AI+ D F + R RT P
Sbjct: 692 NLKKVCGEIAQQEKNIDSLKAAIRAKEDPHEGGSDTPQFTNLPAQRGAVQGPRTVCPGG* 513
Query: 411 LCRDMAQLRLVNEVHEVDDTIQTLQQRLRDAEDTLQSLVHIKATLEYDLAVKANSLYIDQ 470
RD+ R E E + QSL + +LE +++VK NS++ID+
Sbjct: 512 GERDLPVYRRPQEPAE-------------PGGELAQSLQDNRMSLEKEISVKKNSIFIDR 372
Query: 471 EKCMSMRKSYPNTLRLVGF 489
+KCM++R YP+T++L GF
Sbjct: 371 DKCMTVRTRYPSTVKLQGF 315
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000378699 | hsapiens_gene_ensembl | Cell division
control protein 2 homolog (EC 2.7.11.22) (EC 2.7.11.23) (p34 protein
kinase) (Cyclin-dependent kinase 1) (CDK1).
[Source:Uniprot/SWISSPROT;Acc:P06493]
(301 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
01060 398 e-111
14126 252 2e-67
01966 235 3e-64
01756 209 1e-54
32000 206 8e-54
01707 201 3e-52
29581 187 7e-48
04591 174 3e-44
04138 152 1e-37
24241 141 4e-34
03294 131 3e-31
20559 102 1e-26
18921 108 4e-24
13592 97 7e-21
23319 96 2e-20
06405 95 3e-20
00300 91 5e-19
12721 91 7e-19
01718 90 1e-18
15910 89 2e-18
09606 86 3e-17
17975 82 3e-16
28638 63 7e-16
19761 80 7e-16
03508 80 9e-16
14420 79 2e-15
03240 77 8e-15
11780 77 1e-14
12453 76 2e-14
04852 75 3e-14
21808 74 9e-14
19301 73 2e-13
13066 73 2e-13
01392 71 7e-13
21433 59 2e-12
18484 69 2e-12
19094 68 6e-12
18287 65 2e-11
30755 64 5e-11
31885 64 7e-11
27405 64 8e-11
17253 64 1e-10
27546 63 1e-10
26560 63 1e-10
13212 62 2e-10
00392 62 3e-10
26909 61 5e-10
31489 59 2e-09
14116 59 2e-09
07940 59 3e-09
18401 57 8e-09
14477 56 2e-08
22005 55 3e-08
21079 55 5e-08
26711 55 5e-08
28157 54 6e-08
32359 44 2e-07
13840 53 2e-07
00715 49 2e-06
11185 49 3e-06
18996 48 5e-06
16003 48 6e-06
07291 48 6e-06
01106 47 8e-06
13078 47 1e-05
06358 46 1e-05
16708 46 2e-05
16350 45 3e-05
36481 45 4e-05
20640 45 5e-05
05084 44 1e-04
26156 42 1e-04
11404 43 2e-04
12786 42 2e-04
37602 41 8e-04
25019 40 0.001
02638 40 0.001
17300 40 0.001
20152 40 0.001
26009 39 0.003
00638 38 0.004
12672 38 0.005
00394 38 0.006
07836 37 0.007
15549 36 0.015
31789 36 0.017
21800 36 0.020
20773 34 0.059
17644 34 0.089
18481 33 0.16
32357 33 0.17
38560 33 0.20
35032 32 0.29
15931 32 0.42
00832 29 2.4
21210 28 3.3
13305 28 5.8
17516 28 6.1
17806 27 8.5
26052 27 9.1
>01060
Length = 1800
Score = 398 bits (1022), Expect = e-111, Method: Compositional matrix adjust.
Identities = 178/299 (59%), Positives = 229/299 (76%)
Frame = +1
Query: 1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH 60
+ D T +KIGEGTYGVVYK RH+ TG+ +AMKKIRL E+GVPS+AIREI++L+ELRH
Sbjct: 70 LSDLTDFQKIGEGTYGVVYKCRHRATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELRH 249
Query: 61 PNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKVKAQSYLYQILQGI 120
NIV L+DV+M+D RL+L+FEFLSMDLK Y+D P G +D LVK SY++QI+ GI
Sbjct: 250 TNIVCLEDVIMEDERLFLVFEFLSMDLKMYIDKFPEGVVLDRRLVK----SYVFQIVTGI 417
Query: 121 VFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLL 180
FCH RR++HRDLKPQNLLI+ G IK+ADFG+AR F +P+R YTHEVVTLWYR+PE+L+
Sbjct: 418 XFCHQRRIVHRDLKPQNLLINHTGAIKIADFGMARTFALPVRAYTHEVVTLWYRAPEILM 597
Query: 181 GSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQD 240
G+++YSTPVD+WSIGTIFA++ + P+F GDSEIDQLF+IFR +GTP + WPE L
Sbjct: 598 GASKYSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKLPA 777
Query: 241 YKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLDNQIK 299
+ FP WK G L+ + +LD GLDL+ + L DPA+RIS K L H YF ++D +K
Sbjct: 778 FNGMFPLWKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYFLNVDTSVK 954
>14126
Length = 1265
Score = 252 bits (643), Expect = 2e-67, Method: Compositional matrix adjust.
Identities = 144/306 (47%), Positives = 190/306 (62%), Gaps = 11/306 (3%)
Frame = +3
Query: 2 EDYTKIEKIGEGTYGVVYKGRH-KTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELR- 59
+ Y ++ IG G YG VYK R + G+ VAMK+IRL + EEG+P AIREIS+LK+L
Sbjct: 189 QKYEEVAVIGNGAYGTVYKARDLRNQGEFVAMKRIRLNNTEEGMPMMAIREISMLKQLEQ 368
Query: 60 --HPNIVSLQDVLM-----QDSRLYLIFEFLSMDLKKYLDSIP-PGQYMDSSLVKVKAQS 111
HPN+V L DV ++ RL L+FE++ DL YL P PG D + +
Sbjct: 369 YEHPNVVRLLDVSHNTITDREIRLNLVFEYIEHDLATYLAKCPSPGLGPD------RIKD 530
Query: 112 YLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTL 171
+ Q+L G+ F HS R++HRDLKPQNLLI G +KLADFGLAR + + + T VVTL
Sbjct: 531 LMLQLLNGVDFLHSNRIVHRDLKPQNLLISKDGRLKLADFGLARIYSFHMALTT-VVVTL 707
Query: 172 WYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEV 231
WYRSPEVL+ A Y T VDIWS G IFAEL T++ LF G SE DQL +IF +G P
Sbjct: 708 WYRSPEVLM-QAEYGTSVDIWSCGCIFAELFTRRALFKGSSEFDQLKKIFEVIGLPPAGD 884
Query: 232 WPEVESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYF 291
WPE S+ ++N+F P L + V +D DL+ KML++ +RIS + +L HPY
Sbjct: 885 WPEGVSV--HRNSFRPTPPVPLQTLVPEMDPQAKDLMEKMLVFKSGRRISSRESLLHPYL 1058
Query: 292 -NDLDN 296
+DLD+
Sbjct: 1059RDDLDS 1076
>01966
Length = 1735
Score = 235 bits (600), Expect(2) = 3e-64, Method: Compositional matrix adjust.
Identities = 117/227 (51%), Positives = 153/227 (67%), Gaps = 3/227 (1%)
Frame = -1
Query: 22 RHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQDVLMQDSRLYLIFE 81
RH+ TG+ +AMKKIRL E+GVPS+AIREI++L+ELRH NIV L+DV+M+D RL+L+FE
Sbjct: 1651 RHRATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTNIVCLEDVIMEDERLFLVFE 1472
Query: 82 FLSMDLKKYLDSIPPGQYMDSSLVKVKAQSYLYQILQGIVFCHSRRVLHRDLKPQNLLID 141
FLSMDLK Y+D P G +D LVK SY++QI+ GI FCH RR++HRDLKPQNLLI+
Sbjct: 1471 FLSMDLKMYIDKFPEGVVLDRRLVK----SYVFQIVTGINFCHQRRIVHRDLKPQNLLIN 1304
Query: 142 DKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSARYSTPVDIWSIGTI--FA 199
G IK+ADFG+AR F +P+R YTHEVVTLWYR+PE+L+G STP W+ G + +
Sbjct: 1303 HTGAIKIADFGMARTFALPVRAYTHEVVTLWYRAPEILMGPQ--STP-PXWTCGALEPSS 1133
Query: 200 ELATKKPL-FHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNTF 245
+ + PL ++ R +L N P S Q F
Sbjct: 1132 PICSSGPLSSRATPKLTSFLRYSGSLALQRNRRGPSFTSCQHSMACF 992
Score = 27.3 bits (59), Expect(2) = 3e-64, Method: Compositional matrix adjust.
Identities = 11/14 (78%), Positives = 13/14 (92%)
Frame = -2
Query: 6 KIEKIGEGTYGVVY 19
++ KIGEGTYGVVY
Sbjct: 1698 RLSKIGEGTYGVVY 1657
Score = 142 bits (357), Expect = 2e-34, Method: Compositional matrix adjust.
Identities = 62/119 (52%), Positives = 83/119 (69%)
Frame = -3
Query: 181 GSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQD 240
G+++YSTPVD+WSIGTIFA++ + P+F GDSEIDQLF+IFR +GTP + WPE L
Sbjct: 1187 GASKYSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKLPA 1008
Query: 241 YKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLDNQIK 299
+ FP WK G L+ + +LD GLDL+ + L DPA+RIS K L H YF ++D +K
Sbjct: 1007 FNGMFPLWKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYFLNVDTSVK 831
>01756
Length = 1858
Score = 209 bits (533), Expect = 1e-54, Method: Compositional matrix adjust.
Identities = 125/302 (41%), Positives = 181/302 (59%), Gaps = 14/302 (4%)
Frame = -3
Query: 4 YTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNI 63
Y K+ KIG+GT+G V+K R K T QVVAMKK+ +++E+EG P TA+REI +L+ L H N+
Sbjct: 1736 YEKLAKIGQGTFGEVFKARCKKTKQVVAMKKVLMDNEKEGFPITALREIKILQLLNHENV 1557
Query: 64 VSLQDVLMQD--------SRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKVKAQSYLYQ 115
V L ++ S YL+FEF DL L ++ + +L ++K + Q
Sbjct: 1556 VDLIEICSTKATSANRYKSMFYLVFEFCEHDLAGLLSNMS----VVFNLPEIK--EVMKQ 1395
Query: 116 ILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRV---YTHEVVTLW 172
++ G+ + H ++LHRD+K N+LI +G +KLADFGLARAF + +R YT+ VVTLW
Sbjct: 1394 LMNGLYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLW 1215
Query: 173 YRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVW 232
YR PE+LLG YST +D W G I AE+ T+ P+ G +E +QL I + G+ EVW
Sbjct: 1214 YRPPELLLGDRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQNQLTLITQLCGSITPEVW 1035
Query: 233 PEVESLQDYKN-TFPKWKPGSLASHVKNL--DENGLDLLSKMLIYDPAKRISGKMALNHP 289
P VE L+ Y + P+ + ++ D LDLL K+L DP KR++ AL+H
Sbjct: 1034 PGVERLELYNSLDLPQGNKRKVKERLRYYIKDAYALDLLDKLLALDPGKRVNSDEALSHD 855
Query: 290 YF 291
+F
Sbjct: 854 FF 849
>32000
Length = 644
Score = 206 bits (525), Expect = 8e-54, Method: Compositional matrix adjust.
Identities = 93/149 (62%), Positives = 117/149 (78%)
Frame = -1
Query: 146 IKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKK 205
+K+ADFGLAR FG+P+R YTHEV+TLWYR+PE+LLG YS PVDIWS+G IF E+ T++
Sbjct: 572 MKIADFGLARVFGLPVRTYTHEVITLWYRAPEILLGCRFYSVPVDIWSLGCIFVEMMTRR 393
Query: 206 PLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNTFPKWKPGSLASHVKNLDENGL 265
LF GDSEIDQL+RIFR LGTP+ +VWP V L DYK TFPKW +L + V +L + GL
Sbjct: 392 ALFPGDSEIDQLYRIFRTLGTPDEKVWPGVSKLPDYKPTFPKWPLKNLET-VVSLSKVGL 216
Query: 266 DLLSKMLIYDPAKRISGKMALNHPYFNDL 294
DLL +ML Y+P +RIS + A+ HPYFND+
Sbjct: 215 DLLKRMLTYNPNRRISARSAMRHPYFNDM 129
>01707
Length = 757
Score = 201 bits (511), Expect = 3e-52, Method: Compositional matrix adjust.
Identities = 105/226 (46%), Positives = 148/226 (65%), Gaps = 1/226 (0%)
Frame = +1
Query: 1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEG-VPSTAIREISLLKELR 59
ME Y KI KIGEG+YGVV+K R+K T Q+VA+KK +ESE++ + A+REI +LK+L+
Sbjct: 61 MEKYEKIGKIGEGSYGVVFKCRNKETSQLVAIKKF-VESEDDPLIKKIAMREIRMLKQLK 237
Query: 60 HPNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKVKAQSYLYQILQG 119
HPN+V L +V + RL+L+F+++ L LD P G + +VK +YQ L
Sbjct: 238 HPNLVRLIEVFRRKKRLHLVFDYVDHTLLNELDRYPRG--LPEPMVK----RIIYQTLLA 399
Query: 120 IVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVL 179
+ FCH +HRD+KP+N+LI +G +KL DFG AR P YT V T WYR+PE+L
Sbjct: 400 VNFCHQYNTIHRDVKPENILITRQGQVKLCDFGFARILTGPGDEYTDYVATRWYRAPELL 579
Query: 180 LGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALG 225
+G +Y PVD+W+IG +FAEL T + L+ G S++DQL I + LG
Sbjct: 580 VGDTQYGPPVDVWAIGCVFAELLTGQALWPGRSDVDQLHLIRKTLG 717
>29581
Length = 1278
Score = 187 bits (474), Expect = 7e-48, Method: Compositional matrix adjust.
Identities = 99/252 (39%), Positives = 147/252 (58%), Gaps = 3/252 (1%)
Frame = -2
Query: 45 PSTAIREISLLKELRHPNIVSLQDVLMQDS--RLYLIFEFLSMDLKKYLDSIPPGQYMDS 102
PS + L LRH NIV LQ+V++ S L+L+ E+ DL LD++P +
Sbjct: 1223 PSVVCVRSTFLLNLRHQNIVQLQEVVVGKSLDSLFLVMEYCEQDLASLLDNMP------A 1062
Query: 103 SLVKVKAQSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIR 162
+ + + + Q+L+G+ + H ++HRDLK NLL+ DKG +K+ADFGLAR +G P +
Sbjct: 1061 PFSESQVKCIVLQLLKGLRYLHEAFIIHRDLKVSNLLMTDKGCVKIADFGLARNYGKPQK 882
Query: 163 VYTHEVVTLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFR 222
T +VVTLWYR+PE+L GS +ST +D+WS G I EL KPL G S++ Q+ I
Sbjct: 881 PMTPKVVTLWYRAPELLFGSKTHSTAIDMWSAGCILGELLGHKPLMPGRSDLQQIELIME 702
Query: 223 ALGTPNNEVWPEVESLQDYKNTFPKWKP-GSLASHVKNLDENGLDLLSKMLIYDPAKRIS 281
LGTPN+ +WP L ++ K +P +L L E+G+ LL+ + +Y P KR +
Sbjct: 701 LLGTPNDTIWPGFSQLPAFEQFTLKKQPYNNLRHTFPWLSESGIRLLNGLFMYHPQKRAT 522
Query: 282 GKMALNHPYFND 293
+ L H YF +
Sbjct: 521 AEDCLEHSYFKE 486
Score = 32.0 bits (71), Expect = 0.36, Method: Compositional matrix adjust.
Identities = 12/34 (35%), Positives = 23/34 (67%)
Frame = -1
Query: 28 QVVAMKKIRLESEEEGVPSTAIREISLLKELRHP 61
++VA+KK+R+ E G+P + +REI++ + P
Sbjct: 1275 EIVALKKMRMTGERYGIPISGLREINIFAQSATP 1174
>04591
Length = 1117
Score = 174 bits (442), Expect = 3e-44, Method: Compositional matrix adjust.
Identities = 101/262 (38%), Positives = 153/262 (58%), Gaps = 11/262 (4%)
Frame = -2
Query: 41 EEGVPSTAIREISLLKELRHPNIVSLQDVLMQD--------SRLYLIFEFLSMDLKKYLD 92
+EG P TA+REI +L++L H N+V LQ++ S YLIFE+ DL L+
Sbjct: 1101 KEGFPITALREIKILQQLEHENVVQLQEICHTQAGPYNRYKSTFYLIFEYCDYDLAGLLN 922
Query: 93 SIPPGQYMDSSLVKVKAQSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFG 152
++ + SL K + + Q+L G+ + H++++LHRD+K N+L+ G +KLADFG
Sbjct: 921 NL----RVKFSLADKK--NLMSQLLNGLFYIHTKQILHRDIKAANILLTRDGVLKLADFG 760
Query: 153 LARAFGIPIRVYTHEVVTLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDS 212
L+R + + + T+ VVTLWYR PE+LLG Y +D+W +G I AE+ ++KPL G S
Sbjct: 759 LSRPW-VKSKRLTNRVVTLWYRPPELLLGEREYGPEIDMWGVGCIMAEMWSRKPLMQGRS 583
Query: 213 EIDQLFRIFRALGTPNNEVWPEVESLQDY-KNTFPKWKPGSLASHVKNLDEN--GLDLLS 269
E QL I G+ N EVWP V L+ Y K P+ KP + + +L +N G +L+
Sbjct: 582 EQHQLSLITDLCGSLNAEVWPGVTKLELYGKLDLPQGKPRKVKERMLDLLKNKEGAELID 403
Query: 270 KMLIYDPAKRISGKMALNHPYF 291
L DP +R++ AL+H +F
Sbjct: 402 IFLRLDPGQRMNCDNALSHDFF 337
>04138
Length = 800
Score = 152 bits (385), Expect = 1e-37, Method: Compositional matrix adjust.
Identities = 81/185 (43%), Positives = 109/185 (58%), Gaps = 13/185 (7%)
Frame = +1
Query: 120 IVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRV---YTHEVVTLWYRSP 176
+ + H ++LHRD+K N+LI +G +KLADFGLARAF + +R YT+ VVTLWYR P
Sbjct: 52 LYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRPP 231
Query: 177 EVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVE 236
E+LLG YST +D W G I AE+ T+ P+ G +E +QL I + G+ EVWP V
Sbjct: 232 ELLLGDRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQNQLTLITQLCGSITPEVWPGVT 411
Query: 237 SLQDYKNTFPKWKPGSLASHVKNL----------DENGLDLLSKMLIYDPAKRISGKMAL 286
L Y G+LA+ KN+ D GLDL ++L DP++RIS AL
Sbjct: 412 QLSMYHQI-----KGALAAGRKNIIRDRFARILKDPYGLDLFERLLKMDPSQRISADEAL 576
Query: 287 NHPYF 291
NH +F
Sbjct: 577 NHDFF 591
>24241
Length = 413
Score = 141 bits (355), Expect = 4e-34, Method: Compositional matrix adjust.
Identities = 69/119 (57%), Positives = 88/119 (73%), Gaps = 1/119 (0%)
Frame = -2
Query: 6 KIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPN-IV 64
++ KIGEGTYGVVYK RH+ TG+ +AMKKIRL E+GVPS+AIREI++L+ELRH +V
Sbjct: 331 RLSKIGEGTYGVVYKCRHRATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTQXLV 152
Query: 65 SLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKVKAQSYLYQILQGIVFC 123
L+DV+M+D RL+L+FEFLSMDLK Y+D P G +D LVK I+ GI FC
Sbjct: 151 CLEDVIMEDERLFLVFEFLSMDLKMYIDKFPEGVVLDRRLVK---------IVTGINFC 2
>03294
Length = 1684
Score = 131 bits (330), Expect = 3e-31, Method: Compositional matrix adjust.
Identities = 58/112 (51%), Positives = 76/112 (67%)
Frame = -1
Query: 188 PVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNTFPK 247
PVD+WSIGTIFA++ + P+F GDSEIDQLF+IFR +GTP + WPE L + FP
Sbjct: 1675 PVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKLPAFNGMFPL 1496
Query: 248 WKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLDNQIK 299
WK G L+ + +LD GLDL+ + L DPA+RIS K L H YF ++D +K
Sbjct: 1495 WKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYFLNVDTSVK 1340
>20559
Length = 430
Score = 102 bits (255), Expect(3) = 1e-26, Method: Compositional matrix adjust.
Identities = 45/80 (56%), Positives = 65/80 (81%)
Frame = -2
Query: 1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH 60
M+ Y K+EKIGEGTYG V+K +++ T ++VA+K++RL+ ++EGVPS+A+REI LLKEL+H
Sbjct: 378 MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKH 199
Query: 61 PNIVSLQDVLMQDSRLYLIF 80
NIV L DVL + +L L+F
Sbjct: 198 RNIVRLHDVLHSERKLTLVF 139
Score = 29.3 bits (64), Expect(3) = 1e-26, Method: Compositional matrix adjust.
Identities = 18/43 (41%), Positives = 27/43 (62%)
Frame = -3
Query: 80 FEFLSMDLKKYLDSIPPGQYMDSSLVKVKAQSYLYQILQGIVF 122
FE+ DLKKY D+ G+ +D VK S+L+Q+L+G+ F
Sbjct: 140 FEYCDQDLKKYFDTC-NGE-IDPDTVK----SFLHQLLRGLGF 30
Score = 25.4 bits (54), Expect(3) = 1e-26, Method: Compositional matrix adjust.
Identities = 9/14 (64%), Positives = 11/14 (78%)
Frame = -1
Query: 118 QGIVFCHSRRVLHR 131
+ +VFCHS VLHR
Sbjct: 43 EDLVFCHSNNVLHR 2
>18921
Length = 697
Score = 108 bits (269), Expect = 4e-24, Method: Compositional matrix adjust.
Identities = 62/198 (31%), Positives = 113/198 (57%)
Frame = +2
Query: 9 KIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQD 68
K+GEG+YG V+K HK TGQV+A+K++ ++++ + + I+EIS++++ IV
Sbjct: 50 KLGEGSYGSVFKSLHKETGQVLAIKQVPVDTDLQEI----IKEISIMQQCDSKYIVKYYG 217
Query: 69 VLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKVKAQSYLYQILQGIVFCHSRRV 128
+++ L+++ E+ + + + +LV+ + + LY L+G+ + HSRR
Sbjct: 218 SYFKNTDLWIVMEYCGAGSVSDIMRL-----RNKTLVEREIATILYYTLKGLXYLHSRRK 382
Query: 129 LHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSARYSTP 188
+HRD+K N+L++++G KLADFG+A + + T ++ +PEV+ Y
Sbjct: 383 IHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTPYWMAPEVIQ-EIGYDCV 559
Query: 189 VDIWSIGTIFAELATKKP 206
DIWS+G E+A KP
Sbjct: 560 ADIWSLGITALEMAEGKP 613
>13592
Length = 980
Score = 97.1 bits (240), Expect = 7e-21, Method: Compositional matrix adjust.
Identities = 73/286 (25%), Positives = 126/286 (44%), Gaps = 13/286 (4%)
Frame = +2
Query: 9 KIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQD 68
KIG+G +G VY + TG+++AMK+I ++ E E+ +L+ ++H N+V
Sbjct: 5 KIGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETRALKNVAEELKILEGIKHKNLVRYYG 184
Query: 69 VLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKVKAQSYLYQILQGIVFCHSRRV 128
+ + L + E S + L + G L + ++ + Q+L G+ H +
Sbjct: 185 IEVHREELLIFMELCSEGTLESLVELTGG------LPEALSRRFTAQLLSGVAELHKHGI 346
Query: 129 LHRDLKPQNL-LIDDKGTIKLADFGLARAFGIPIRVYTHEVV---------TLWYRSPEV 178
+HRD+K N+ L+D ++KL DFG A +++ H V T Y +PEV
Sbjct: 347 VHRDIKTANIFLVDGSNSLKLGDFGSA------VKIQAHTTVPGELQGYVGTQAYMAPEV 508
Query: 179 L--LGSARYSTPVDIWSIGTIFAELAT-KKPLFHGDSEIDQLFRIFRALGTPNNEVWPEV 235
S + DIWS+G + E+A+ K+P ++ D F+I +G PE
Sbjct: 509 FTKTNSDGHGRLADIWSVGCVVVEMASGKRPW----AQFDSNFQIMFKVGMGEKPQAPE- 673
Query: 236 ESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRIS 281
+L + G D + L +DP +R+S
Sbjct: 674 -----------------------SLSQEGHDFIDHCLQHDPKQRLS 742
>23319
Length = 2235
Score = 95.9 bits (237), Expect = 2e-20, Method: Compositional matrix adjust.
Identities = 51/118 (43%), Positives = 71/118 (60%), Gaps = 2/118 (1%)
Frame = +3
Query: 185 YSTPVDIWSIGTIFAELATK-KPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKN 243
YST +D+WS G IFAELA +PLF G+ + DQL RIF+ LGTP + WP + L +Y+
Sbjct: 27 YSTSIDMWSAGCIFAELANAGRPLFPGNDDDDQLKRIFKLLGTPTEDQWPGMTQLPNYR- 203
Query: 244 TFPKWKPGSLASH-VKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLDNQIKK 300
FP + + V L+ G DLL +L+ P+ R+S AL HPYF DL +++
Sbjct: 204 MFPMYHVTTTWQQVVPKLNSKGRDLLQCLLVCCPSDRMSADEALQHPYFADLPPLVRQ 377
>06405
Length = 1965
Score = 95.1 bits (235), Expect = 3e-20, Method: Compositional matrix adjust.
Identities = 68/232 (29%), Positives = 120/232 (51%), Gaps = 11/232 (4%)
Frame = +1
Query: 9 KIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQD 68
++G G YG VY+ K ++VA+K ++ E+ + + E +++KE++HPN+V L
Sbjct: 280 RLGGGQYGDVYEAMWKRYNKIVAVKTLK---EDTMALNDFLEEAAIMKEMKHPNLVQLLG 450
Query: 69 VLMQDSRLYLIFEFLSM-DLKKYLDSIPPGQYMDSSLVKVKAQSYLYQILQGIVFCHSRR 127
V ++ Y++ EF+ +L YL S + ++L+ + Q I G+ + ++
Sbjct: 451 VCTREPPFYIVTEFMPHGNLLDYLRSSTREENGPTALMYMATQ-----IASGMAYLETKN 615
Query: 128 VLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEV---VTLWYRSPEVLLGSAR 184
+HRDL +N L+ D +K+ADFGLAR YT + + + +PE L + R
Sbjct: 616 FIHRDLAARNCLVADSNMVKVADFGLARLMK--DDTYTAHIGAKFPIKWTAPEGLAFN-R 786
Query: 185 YSTPVDIWSIGTIFAELATKKPLFHGDSEIDQL-------FRIFRALGTPNN 229
+ST DIW+ G + ELAT + E+ ++ +R+ R GTP +
Sbjct: 787 FSTRSDIWAFGVLLWELATYGMSPYPGVELTEVYHLLERGYRMERPPGTPAD 942
>00300
Length = 2318
Score = 91.3 bits (225), Expect = 5e-19, Method: Compositional matrix adjust.
Identities = 68/291 (23%), Positives = 129/291 (44%), Gaps = 9/291 (3%)
Frame = -1
Query: 9 KIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQD 68
KIGEG +G VY + +TG+++A+K+++ + + EI + + ++H N+V
Sbjct: 1637 KIGEGQFGKVYTAVNMSTGELMALKEMKFQPNDLQQLREMCDEIKIFEGIQHENLVKYYG 1458
Query: 69 VLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKVKAQSYLYQILQGIVFCHSRRV 128
V + + + E Y D+ + L + + Y +I+ + H +
Sbjct: 1457 VEVHKDEMLMFME--------YCDTGTIEEAAKMGLPEYLIRRYTREIVLAVNHLHENSI 1302
Query: 129 LHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYT------HEVV-TLWYRSPEVLLG 181
+HRD+K N+ + G +KL DFG + + ++ +T H +V T Y +PEV
Sbjct: 1301 VHRDIKGANIFLTSNGHVKLGDFGCS----VKLKSHTTMPGEFHNLVGTTAYMAPEVFTQ 1134
Query: 182 SAR--YSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQ 239
+ + Y DIWS+G + E+AT K +H ++D ++I +G + P+ S++
Sbjct: 1133 NDQGGYGRAADIWSLGCVVIEMATGKRPWH---DLDNNYQIMYKVGIGHKPAVPDSLSVE 963
Query: 240 DYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPY 290
G L ++ +DPA+R L+H +
Sbjct: 962 ------------------------GKHFLDLIMCHDPAQRALASQLLDHTF 882
>12721
Length = 821
Score = 90.5 bits (223), Expect = 7e-19, Method: Compositional matrix adjust.
Identities = 58/212 (27%), Positives = 105/212 (49%)
Frame = +1
Query: 9 KIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQD 68
KIGEG+ G+V + G+ +A+KK+ L ++ E+ ++++ HPNIV + +
Sbjct: 109 KIGEGSTGIVCIATSRD-GRQMAVKKMDLRKQQRR--ELLFNEVVVMRDYHHPNIVEMYN 279
Query: 69 VLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKVKAQSYLYQILQGIVFCHSRRV 128
+ + L+++ EF+ L I MD +V+ + L+ + F H+ V
Sbjct: 280 SYLVNDELWVVMEFME---GGALTDIVTNNRMD----EVQIATVCRACLKALAFLHANGV 438
Query: 129 LHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSARYSTP 188
+HRD+K ++L+ G +KL DFG ++ V T ++ +PEV + Y
Sbjct: 439 IHRDIKSDSILLSHDGKVKLXDFGFCAQVTQDLQKRKSLVGTPYWMAPEV-ISRLPYGPE 615
Query: 189 VDIWSIGTIFAELATKKPLFHGDSEIDQLFRI 220
VDIWS+G + E+ +P F + + + RI
Sbjct: 616 VDIWSLGIMVMEMIDAEPPFFNEPPLQAMRRI 711
>01718
Length = 959
Score = 89.7 bits (221), Expect = 1e-18, Method: Compositional matrix adjust.
Identities = 64/206 (31%), Positives = 108/206 (52%), Gaps = 6/206 (2%)
Frame = +3
Query: 7 IEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSL 66
EKIG G + V+K H+ TGQV+A+K + S + +RE+ LL L+H NI+
Sbjct: 162 CEKIGAGFFSEVFKVTHRITGQVMALKMNTMTSNRHNM----LREVQLLNRLQHANILRF 329
Query: 67 QDVLMQDSRLYLIFEFL-SMDLKKYLDSIPPGQYMDSSLVKVKAQSYLYQILQGIVFCHS 125
V + + +L+ + E++ S +L++ L+ D L + + +G+ + HS
Sbjct: 330 MGVCVHEGQLHALTEYIPSGNLEQLLEK------KDEELPWTQRIQLTLGLARGLDYLHS 491
Query: 126 RRVLHRDLKPQNLLI---DDKG-TIKLADFGLARAFGIPI-RVYTHEVVTLWYRSPEVLL 180
R +HRDL +N+LI D+ G +ADFGLA P+ + V + ++ +PEVL
Sbjct: 492 TRFIHRDLTSKNILIRREDNHGYHAVIADFGLATKIPDPLDKEKLPTVGSPYWMAPEVLN 671
Query: 181 GSARYSTPVDIWSIGTIFAELATKKP 206
G Y+ D++S+G I E+ + P
Sbjct: 672 GHF-YNERADLFSVGIIMCEITARIP 746
>15910
Length = 1361
Score = 89.0 bits (219), Expect = 2e-18, Method: Compositional matrix adjust.
Identities = 62/208 (29%), Positives = 96/208 (46%), Gaps = 3/208 (1%)
Frame = +2
Query: 97 GQYMDSSLVKVKAQSYLYQILQGIVFCHSRRVLHRDLKPQNLL---IDDKGTIKLADFGL 153
GQY + A + IL G+ + H+ V+HRDLKP+NLL + D +KLADFGL
Sbjct: 449 GQYTEKD-----AARAISDILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLADFGL 613
Query: 154 ARAFGIPIRVYTHEVVTLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSE 213
+R +++ T T Y +PEVL G +Y+ VD+WS+G I L F ++E
Sbjct: 614 SRIIEPEVQMSTV-CGTPGYCAPEVLKGD-KYTPSVDMWSVGVIAYILLCGYEPFFAENE 787
Query: 214 IDQLFRIFRALGTPNNEVWPEVESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLI 273
+ +I + + E W E+ EN D++ K+L+
Sbjct: 788 FEMYRKIIKGEYKFDEEYWSEI-------------------------SENAKDVVRKLLV 892
Query: 274 YDPAKRISGKMALNHPYFNDLDNQIKKM 301
DP KR++ AL P+ + + M
Sbjct: 893 IDPKKRLTATEALRLPWVKGVATKTTNM 976
>09606
Length = 1300
Score = 85.5 bits (210), Expect = 3e-17, Method: Compositional matrix adjust.
Identities = 59/234 (25%), Positives = 103/234 (44%), Gaps = 22/234 (9%)
Frame = -3
Query: 1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH 60
ME++ E++G+G + ++YKGR K T VA+ I E + + ++ H
Sbjct: 1118 MENFVLYEELGKGEHSIIYKGRRKGTINFVAIHCIEKCKRPE-----VTNTVRMTHDISH 954
Query: 61 PNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKVKAQSYLYQILQGI 120
PN+V + + L+L+ E + S+ D L + + + ++ G+
Sbjct: 953 PNVVQFHEWYETSNHLWLVVELCTGG------SLADILAQDHHLPETSIRDFGIHLVTGL 792
Query: 121 VFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIR---VYTHEVVTLW----- 172
+ HS +L DL+P +L+D G +K ADFGL++ G + E W
Sbjct: 791 HYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQWNIQSA 612
Query: 173 --------------YRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDS 212
Y +PEV G A S D+W++G +F E+ + P F G++
Sbjct: 611 EEMMKQVPTSGSPTYMAPEVFQG-AEPSIMSDLWALGCVFYEMFSGHPPFLGET 453
>17975
Length = 449
Score = 81.6 bits (200), Expect = 3e-16, Method: Compositional matrix adjust.
Identities = 51/144 (35%), Positives = 80/144 (55%), Gaps = 2/144 (1%)
Frame = +3
Query: 15 YGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQDVLMQDS 74
+ VV RH TG+ VA+K I +E S +E+ +K ++HPN+V L +V+ +
Sbjct: 6 FAVVKLARHVFTGEKVAVKVIDKTKLDEVSRSHLFQEVRCMKLVQHPNVVRLYEVIDTQT 185
Query: 75 RLYLIFEFL-SMDLKKYLDSIPPGQYMDSSLVKVKAQSYLYQILQGIVFCHSRRVLHRDL 133
+LYLI E D+ Y+ G ++ L A+ Y QI++ I +CH V+HRDL
Sbjct: 186 KLYLILELGDGGDMYDYIMRHSGG--LEEKL----AKRYFRQIVEAISYCHKLHVVHRDL 347
Query: 134 KPQNLLIDDK-GTIKLADFGLARA 156
KP+N++ +K G +KL DFG +
Sbjct: 348 KPENVVFFEKPGLVKLTDFGFSTC 419
>28638
Length = 1458
Score = 62.8 bits (151), Expect(2) = 7e-16, Method: Compositional matrix adjust.
Identities = 33/81 (40%), Positives = 52/81 (64%), Gaps = 2/81 (2%)
Frame = -1
Query: 128 VLHRDLKPQNLLIDD--KGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSARY 185
++H DLKP+N+L+ + + IK+ DFG + G R+Y + + + +YRSPEVLLG Y
Sbjct: 768 IIHCDLKPENILLCNPKRSAIKIVDFGSSCQLG--QRIYQY-IQSRFYRSPEVLLG-VPY 601
Query: 186 STPVDIWSIGTIFAELATKKP 206
+D+WS+G I E+ T +P
Sbjct: 600 DLAIDMWSLGCILVEMHTGEP 538
Score = 38.1 bits (87), Expect(2) = 7e-16, Method: Compositional matrix adjust.
Identities = 33/126 (26%), Positives = 50/126 (39%), Gaps = 34/126 (26%)
Frame = -2
Query: 206 PLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNTFP-------------KWK-PG 251
PLF G +E DQ+ +I LG P + + + + Y + P K+K P
Sbjct: 539 PLFAGSNEFDQMMKIVEVLGVPPRHILDQAQKTRKYFDLLPDGTYAPKKPRDNKKYKSPS 360
Query: 252 SLASHV-----------KNLDENG---------LDLLSKMLIYDPAKRISGKMALNHPYF 291
S H + + E G DL+ +ML +DP RIS AL H +F
Sbjct: 359 SRKLHEVLGAEKGGPGGRRMGEPGHTVADYLKFKDLILRMLDFDPKTRISPYYALQHNFF 180
Query: 292 NDLDNQ 297
++
Sbjct: 179 RKTSDE 162
>19761
Length = 473
Score = 80.5 bits (197), Expect = 7e-16, Method: Compositional matrix adjust.
Identities = 42/117 (35%), Positives = 66/117 (56%), Gaps = 2/117 (1%)
Frame = -3
Query: 111 SYLYQILQGIVFCHSRR--VLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEV 168
+L Q + + H+ +LHRDLKPQN+ + +KG ++L D GLAR P T +V
Sbjct: 411 CWLMQTASALNYMHTHTPVILHRDLKPQNIYVTEKGDVRLGDLGLARKLTGPADFATSQV 232
Query: 169 VTLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALG 225
T+ Y SPE+ L Y++ DIWS+G +F ++ KK G E+ +F + + +G
Sbjct: 231 GTIMYLSPEI-LSQQPYNSKSDIWSLGCVFYDITGKK----GSDEMGVMFLLVQVMG 76
>03508
Length = 1463
Score = 80.5 bits (197), Expect = 9e-16, Method: Compositional matrix adjust.
Identities = 61/209 (29%), Positives = 109/209 (52%), Gaps = 5/209 (2%)
Frame = +1
Query: 2 EDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH- 60
+DY + K+G G Y V++ + T + K ++ + REI +L+ LR
Sbjct: 589 DDYQIVRKLGRGKYSEVFEAINVTNNE-----KCVIKILKPVKKKKIKREIKILENLRGG 753
Query: 61 PNIVSLQDVLMQD-SRL-YLIFEFLS-MDLKKYLDSIPPGQYMDSSLVKVKAQSYLYQIL 117
N+++L ++ SR LIFE ++ D K+ + + + YLY+++
Sbjct: 754 TNVITLLAIVKDPVSRTPALIFEHVNNTDFKQ----------LYQTFTDYDIRFYLYELM 903
Query: 118 QGIVFCHSRRVLHRDLKPQNLLID-DKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSP 176
+ + FCHS ++HRD+KP N++ID + ++L D+GLA F P Y V + +++ P
Sbjct: 904 KALDFCHSMGIMHRDVKPHNVMIDHENKKLRLIDWGLAE-FYHPGMEYNVRVASRYFKGP 1080
Query: 177 EVLLGSARYSTPVDIWSIGTIFAELATKK 205
E+LL Y +D+WS+G +FA + +K
Sbjct: 1081ELLLDYQMYDYSLDMWSLGCMFASMIFRK 1167
Score = 52.8 bits (125), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 35/114 (30%), Positives = 55/114 (48%), Gaps = 14/114 (12%)
Frame = +2
Query: 192 WSIGTIFAEL----ATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQ-DYKNTF- 245
W+ G A L + K P FHG DQL RI + LGT ++++ +E Q D F
Sbjct: 1118 WTCGVWAACLPA*SSGKSPFFHGHDNYDQLVRIAKVLGT--DDLYGYIEKYQIDLDPRFN 1291
Query: 246 --------PKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYF 291
+W+ + + + LD L K+L YD +R++ + A++HPYF
Sbjct: 1292 DILGRHSRKRWERFVHSENQHLISPEALDFLDKLLRYDHNERLTAREAMDHPYF 1453
>14420
Length = 528
Score = 79.3 bits (194), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 48/169 (28%), Positives = 85/169 (50%)
Frame = +2
Query: 49 IREISLLKELRHPNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKVK 108
I EI +++E ++PNIV+ D + L+++ EFL+ L + MD +
Sbjct: 44 INEILVMRENQNPNIVNYLDSYLVGEELWVVMEFLA---GGSLTDVVTETCMDEGQIAAV 214
Query: 109 AQSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEV 168
+ + LQ + F H +V+HRD+K N+L+ G++KL DFG + V
Sbjct: 215 CR----ECLQALEFLHENQVIHRDIKSDNILLGMDGSVKLTDFGFCAQLSPEQSKRSTMV 382
Query: 169 VTLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQL 217
T ++ +PEV+ +Y VDIWS+G + E+ +P + ++ + L
Sbjct: 383 GTPYWMAPEVVT-RKQYGPTVDIWSLGVMCIEMIEGEPPYLNENPLRAL 526
>03240
Length = 1683
Score = 77.0 bits (188), Expect = 8e-15, Method: Compositional matrix adjust.
Identities = 67/272 (24%), Positives = 113/272 (41%), Gaps = 54/272 (19%)
Frame = -3
Query: 4 YTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNI 63
+ KI+ +G G +G V R TG + AMK +R+ +LK + ++
Sbjct: 1285 FEKIKTLGVGAFGEVSLCRKNDTGMLYAMK--------------TLRKSDVLKRNQVAHV 1148
Query: 64 VSLQDVLMQDSRLYLIFEFLSMDLKKYL----DSIPPGQYMDSSLVKVK------AQSYL 113
+ +D+L + +++ + S YL D +P G M L++++ A+ Y+
Sbjct: 1147 KAERDILAEADNEWVVKLYYSFQDHNYLYFVMDYVPGGDLM-GLLIRMEILDEPLARFYV 971
Query: 114 YQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFG--------------- 158
+++Q I H +HRD+KP N+LID G IKL DFGL F
Sbjct: 970 AELVQAIESVHRMGFIHRDIKPDNILIDRNGHIKLTDFGLCTGFRWTHNSKYYQRDGTHA 791
Query: 159 --------------------IPI--------RVYTHEVV-TLWYRSPEVLLGSARYSTPV 189
P+ R H +V T Y +PEVL Y++
Sbjct: 790 RQDSMEVKCQLDEQCQCEILKPLERRRKREQRCLAHSLVGTPNYIAPEVLSRLGGYTSVC 611
Query: 190 DIWSIGTIFAELATKKPLFHGDSEIDQLFRIF 221
D WS+G I E+ P F+ ++ + +++
Sbjct: 610 DWWSVGVILFEMLVGHPPFYANTPAETQYKVI 515
>11780
Length = 1713
Score = 76.6 bits (187), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 52/153 (33%), Positives = 92/153 (60%), Gaps = 2/153 (1%)
Frame = +3
Query: 8 EKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQ 67
E IG+G +G VYKG ++ GQ VA+K+++ + E + ++E S++ LRH N+V L
Sbjct: 615 EAIGKGDFGDVYKGMYR--GQPVAIKQLKDKDRGE---QSFLQEASVMTSLRHDNLVRLI 779
Query: 68 DVLMQDSRLYLIFEFLSM-DLKKYLDSIPPGQYMDSSLVKVKAQ-SYLYQILQGIVFCHS 125
V++ ++ ++L+ EF+ +L +YL S S++ K Q ++ + + S
Sbjct: 780 GVVLGET-IFLVTEFMGKGNLVEYLRS------RGRSVITKKDQINFATDTCAAMEYLES 938
Query: 126 RRVLHRDLKPQNLLIDDKGTIKLADFGLARAFG 158
+R++HRDL +N+L+ D G K++DFGLA+ FG
Sbjct: 939 KRLVHRDLAARNVLVHDDGKAKVSDFGLAK-FG 1034
>12453
Length = 680
Score = 76.3 bits (186), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 38/102 (37%), Positives = 57/102 (55%), Gaps = 1/102 (0%)
Frame = +3
Query: 194 IGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKN-TFPKWKPGS 252
+G IF E+A +PLF G + D+L IF+ LGTP + P + D+ P ++ +
Sbjct: 6 VGCIFYEMACGRPLFPGSTVEDELHLIFKTLGTPTEDSLPSISRNPDFLALNLPHYQGEA 185
Query: 253 LASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDL 294
L + LD +GLDLL+K L Y+ R+S +L H +FN L
Sbjct: 186 LITIAPRLDSDGLDLLAKFLKYNAKIRVSAADSLKHSFFNSL 311
>04852
Length = 1462
Score = 75.1 bits (183), Expect = 3e-14, Method: Compositional matrix adjust.
Identities = 53/184 (28%), Positives = 91/184 (49%), Gaps = 29/184 (15%)
Frame = +1
Query: 47 TAIREISLLKELR----------HPNIVSLQDVLMQDSRLYLIFEFL-SMDLKKYLDSI- 94
TA+ E ++EL+ H NIV+ Q L++I EF + +L+ +L+S
Sbjct: 58 TAVEEQDFVQELQVMKAVKKMGSHINIVNFLGCCTQGGPLWVIVEFAKNGNLRDFLESCR 237
Query: 95 -------------PPGQYMDSS----LVKVKAQSYLYQILQGIVFCHSRRVLHRDLKPQN 137
PG Y + + + SY +QI +G+ F SR+ +HRDL +N
Sbjct: 238 DGINGYGKFVSPQDPGWYTKTPGGHVIRRKNLLSYAFQIARGMEFLASRKCIHRDLAARN 417
Query: 138 LLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSARYSTPVDIWSIGTI 197
+L+ ++ +K+ADFGL+R G + + + + + +PE L RY+T D+WS G +
Sbjct: 418 VLVTEEHVLKIADFGLSRT-GDYYKKRSGGRLPVKWMAPEALF-DMRYTTKSDVWSFGVV 591
Query: 198 FAEL 201
E+
Sbjct: 592 LWEI 603
>21808
Length = 1011
Score = 73.6 bits (179), Expect = 9e-14, Method: Compositional matrix adjust.
Identities = 50/164 (30%), Positives = 84/164 (51%), Gaps = 5/164 (3%)
Frame = +1
Query: 45 PSTAIREISLLKELRHPNIVSLQDVLMQDSRLYLIFEFL-SMDLKKYLDSIPPGQYMD-S 102
P + E ++K+LRHP ++ L V QD +++I E + + L ++L G+ +
Sbjct: 64 PKDFLAEAQIMKKLRHPKLIQLYAVCTQDDPIFIITELMKNGSLLEFLQG--KGRVLKLP 237
Query: 103 SLVKVKAQSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIR 162
+L+ + AQ I G+ + S+ +HRDL +N+L+ D T+K+ADFGLAR I
Sbjct: 238 ALIDIGAQ-----IACGMAYLESQNYIHRDLAARNILVSDNNTVKIADFGLARV--IKED 396
Query: 163 VYTHEV---VTLWYRSPEVLLGSARYSTPVDIWSIGTIFAELAT 203
Y V + + +PE R++ D+WS G + E T
Sbjct: 397 EYEARVGARFPIKWTAPEA-ANYNRFTIKSDVWSFGILLTETVT 525
>19301
Length = 712
Score = 72.8 bits (177), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 49/158 (31%), Positives = 77/158 (48%), Gaps = 4/158 (2%)
Frame = +2
Query: 1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH 60
E T +E +G G G V+ G K + VA+KK+R + T IR L++L H
Sbjct: 302 FESITDLEWLGSGAQGAVFLG--KLCAEEVAVKKVR------DIKETDIRN---LRKLNH 448
Query: 61 PNIVSLQDVLMQDSRLYLIFEFLSM----DLKKYLDSIPPGQYMDSSLVKVKAQSYLYQI 116
PNI+S + V Q +I E+ ++ + IPP +D S QI
Sbjct: 449 PNIISFKGVCTQAPCYCIIMEYCPYGQLYEVLRDGKEIPPALVLDWS----------KQI 598
Query: 117 LQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLA 154
G+ + HS +++HRDLK N+L+ +K++DFG +
Sbjct: 599 ASGMNYLHSHKIIHRDLKSPNVLVAKNDVVKISDFGTS 712
>13066
Length = 551
Score = 72.8 bits (177), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 54/192 (28%), Positives = 87/192 (45%), Gaps = 8/192 (4%)
Frame = +3
Query: 12 EGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQDVLM 71
GT+ Y K +++ +K ++ E+ P RE+ LL +L HP I+ + +L
Sbjct: 21 HGTFNDGYGRNIKLACKIIDKEKAPVDFVEKFFP----RELDLLTKLDHPYIIQIHSILQ 188
Query: 72 QDSRLYLIFEFLSM-DLKKYLDSIPPGQYMDSSLVKVK-AQSYLYQILQGIVFCHSRRVL 129
+ + ++ F DL Y+ + VK K A+ + YQ+ + + HS V
Sbjct: 189 RXPKNFIFMRFAERGDLLTYIQEV--------GFVKEKQAKIWFYQMTTALNYLHSYDVA 344
Query: 130 HRDLKPQNLLIDDKGTIKLADFGLARAF------GIPIRVYTHEVVTLWYRSPEVLLGSA 183
HRDLK +N+L+ +KLADFG A A R Y Y +PE++ G+
Sbjct: 345 HRDLKCENILLSSHFNVKLADFGFACACITESGEKYMSRTYCGSAA---YAAPEIVYGAP 515
Query: 184 RYSTPVDIWSIG 195
D WS+G
Sbjct: 516 YAPKVADAWSLG 551
>01392
Length = 1806
Score = 70.9 bits (172), Expect = 7e-13, Method: Compositional matrix adjust.
Identities = 57/200 (28%), Positives = 89/200 (44%), Gaps = 12/200 (6%)
Frame = -1
Query: 104 LVKVKAQSYLYQILQGIVFCHSRRVLHRDLKPQNLL---IDDKGTIKLADFGLARAF--- 157
L + +A + I + + F HS+ + HRDLKP+N+L +DD +K+ DF LA
Sbjct: 1800 LCEREASLVVRHIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGISCD 1621
Query: 158 --GIPIRVYTHEVVTLWYRSPEVLLG----SARYSTPVDIWSIGTIFAELATKKPLFHGD 211
G V + Y +PEV+ S Y D+WS+G I + P F+G
Sbjct: 1620 GDGTKTPELLTPVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILYIMLCGYPPFYGQ 1441
Query: 212 SEIDQLFRIFRALGTPNNEVWPEVESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKM 271
D + A + ++ S+QD FP + S++S K DL+ +
Sbjct: 1440 CGEDCGWNRGEACHDCQDMLF---NSIQDGHYKFPSQEWTSISSSAK-------DLIRHL 1291
Query: 272 LIYDPAKRISGKMALNHPYF 291
L+ +P KR S L HP+
Sbjct: 1290 LVREPRKRYSAADVLKHPWI 1231
>21433
Length = 590
Score = 58.9 bits (141), Expect(2) = 2e-12, Method: Compositional matrix adjust.
Identities = 37/99 (37%), Positives = 56/99 (56%)
Frame = +2
Query: 108 KAQSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHE 167
+ Y+YQ+ + +CH R+V+HRD+KP+NLL+ KG +K+ADFG + P T
Sbjct: 170 RTACYIYQLSSALEYCHYRKVIHRDIKPENLLLGLKGDLKIADFGW--SVHAPSSRRTTM 343
Query: 168 VVTLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKP 206
TL Y PE++ G + VD+WS+G + E P
Sbjct: 344 CGTLDYLPPEMVEGKT-HDENVDLWSLGVLCYEFLVGTP 457
Score = 30.4 bits (67), Expect(2) = 2e-12, Method: Compositional matrix adjust.
Identities = 14/33 (42%), Positives = 19/33 (57%)
Frame = +3
Query: 50 REISLLKELRHPNIVSLQDVLMQDSRLYLIFEF 82
REI + LRH NI+ + +R+YLI EF
Sbjct: 15 REIEIQSHLRHDNILRMFGYFHDKTRVYLILEF 113
>18484
Length = 635
Score = 68.9 bits (167), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 49/174 (28%), Positives = 82/174 (47%), Gaps = 1/174 (0%)
Frame = +1
Query: 109 AQSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEV 168
A Y +I G+ F H + +++RDLK N+++D +G IK+ADFG+ + G+ T
Sbjct: 49 AAFYAAEIAVGLFFLHDQGIIYRDLKLDNVMLDSEGHIKIADFGMCKE-GMTGDATTRTF 225
Query: 169 V-TLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTP 227
T Y +PE++L YS VD W+ G + E+ +P F G+ E D+LF
Sbjct: 226 CGTPDYIAPEIVL-YQPYSKSVDWWAYGVLLFEMLAGQPPFDGEDE-DELF--------- 372
Query: 228 NNEVWPEVESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRIS 281
S+ D+ ++P K + + L +L+ +P KR+
Sbjct: 373 --------SSITDHNVSYP-----------KAMSREAVSLCKGLLMKNPTKRLG 477
>19094
Length = 898
Score = 67.8 bits (164), Expect = 6e-12, Method: Compositional matrix adjust.
Identities = 36/102 (35%), Positives = 60/102 (58%)
Frame = +1
Query: 101 DSSLVKVKAQSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIP 160
+ +LV+ + + LY L+G+ + HSRR +HRD+K N+L++++G KLADFG+A
Sbjct: 40 NKTLVEREIATILYYTLKGL*YLHSRRKIHRDIKAGNILLNNEGHAKLADFGVAGQLTDT 219
Query: 161 IRVYTHEVVTLWYRSPEVLLGSARYSTPVDIWSIGTIFAELA 202
+ + T ++ +PEV+ Y DIWS+G E+A
Sbjct: 220 MAKRNTVIGTPYWMAPEVIQ-EIGYDCVADIWSLGITALEMA 342
>18287
Length = 678
Score = 65.5 bits (158), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 37/112 (33%), Positives = 60/112 (53%), Gaps = 3/112 (2%)
Frame = -3
Query: 185 YSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNE-VWPEVESLQDY-- 241
Y +DIWS+G IFAEL +++ LF + QL I +GTP E + E +++
Sbjct: 673 YDYSIDIWSVGCIFAELLSRRILFQAQGPVQQLDMIINLVGTPRPEDMERACEGARNHIL 494
Query: 242 KNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFND 293
F + +L + + + LL++MLI +P RIS + AL+HPY ++
Sbjct: 493 NQPFRRQNLLTLYNLSPHATHEAVRLLTRMLILNPKNRISAEEALSHPYLDE 338
>30755
Length = 1137
Score = 64.3 bits (155), Expect = 5e-11, Method: Compositional matrix adjust.
Identities = 54/194 (27%), Positives = 87/194 (44%), Gaps = 6/194 (3%)
Frame = +2
Query: 108 KAQSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHE 167
+ + Y +I+ + + HS+ +++RDLK +NLL+D G IK+ADFGL + R
Sbjct: 35 RTRFYGAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCKEDITYGRTTKTF 214
Query: 168 VVTLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKK-PLFHGDSEIDQLFRIFRALGT 226
T Y +PEV L Y VD W G + E+ + P ++ D ++ LF +
Sbjct: 215 CGTPEYLAPEV-LDDNDYGRAVDWWGTGVVMYEMICGRLPFYNRDHDV--LFTLIL---- 373
Query: 227 PNNEVWPEVESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISG---- 282
++D K FP +N+ + LLS +L DP R+ G
Sbjct: 374 -----------VEDVK--FP-----------RNITDEAKSLLSGLLAKDPRNRLGGGQDD 481
Query: 283 -KMALNHPYFNDLD 295
K HP+F ++
Sbjct: 482 VKEIQAHPFFASIN 523
>31885
Length = 529
Score = 63.9 bits (154), Expect = 7e-11, Method: Compositional matrix adjust.
Identities = 48/179 (26%), Positives = 88/179 (49%), Gaps = 7/179 (3%)
Frame = -2
Query: 52 ISLLKELRHPNIVSLQDVLMQDSRLYLIFE-FLSMDLKKYLDSIPPGQYMDSSLVKVKAQ 110
+ +L L HP +V+L + L+++ + FL DL+ ++ + S + +
Sbjct: 519 VDMLTRLDHPFLVNLWYAFQDEEDLFMVVDLFLGGDLRYHMQQ-------EVSFREDCVK 361
Query: 111 SYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVT 170
YL Q+ + + S++++HRD+KP N+L+D++G + DF +A + T T
Sbjct: 360 FYLCQLALVLDYLRSQKIVHRDIKPDNILLDEQGHCHVTDFNIATQLE-DDELATSTSGT 184
Query: 171 LWYRSPEVL---LGSAR-YSTPVDIWSIGTIFAELATKKPLF--HGDSEIDQLFRIFRA 223
Y +PEV + R Y PVD WS+G EL K+ F H ++ + +++ A
Sbjct: 183 RPYMAPEVYGVAINERRGYGFPVDWWSLGVSLFELLKKRRPFSVHSNTSLHEMWATMVA 7
>27405
Length = 532
Score = 63.9 bits (154), Expect = 8e-11, Method: Compositional matrix adjust.
Identities = 51/183 (27%), Positives = 88/183 (48%), Gaps = 7/183 (3%)
Frame = -3
Query: 15 YGVVYKGRHKTTGQVVAMKKI-RLESEEEGVPSTAIREISLLKELR----HPNIVSLQDV 69
+G VY R TG++ AMK + + + +G + A+ E +L + P IV +
Sbjct: 527 FGEVYGCRKADTGKMYAMKCLDKKRIKMKGGETLALNERIMLSLVSTGEGSPFIVCMTYA 348
Query: 70 LMQDSRLYLIFEFLSM-DLKKYLDSIPPGQYMDSSLVKVKAQSYLYQILQGIVFCHSRRV 128
+L I + ++ DL +L + + + Y +++ G+ HSR V
Sbjct: 347 FQTPEKLCFILDLMNGGDLHYHLSQ-------HGVFTEKEVRFYAAEVMLGLEHMHSRFV 189
Query: 129 LHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVV-TLWYRSPEVLLGSARYST 187
++RDLKP N+L+D+ G ++++D GLA F + H V T Y +PEVL+ Y +
Sbjct: 188 VYRDLKPANILLDENGHVRISDLGLACDFS---KKKPHASVGTHGYMAPEVLMKGQAYDS 18
Query: 188 PVD 190
D
Sbjct: 17 SAD 9
>17253
Length = 483
Score = 63.5 bits (153), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 39/140 (27%), Positives = 75/140 (53%), Gaps = 7/140 (5%)
Frame = -1
Query: 38 ESEEEGVPSTAIREISLLKEL-RHPNIVSLQDVLMQDSRLYLIFEFLSM-DLKKYLDSIP 95
E+ + S +RE+S++++L RHPN+VS ++ EF DL +L
Sbjct: 438 EAATDAEKSEFLRELSIMRKLPRHPNVVSFMGCCTMSDPALILMEFCCHGDLLSFLRKRR 259
Query: 96 PGQ--YMDSSLVKVKAQ---SYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLAD 150
P + ++ S+ + A+ S+ + +G+ + +++HRD+ +N+LI ++ K++D
Sbjct: 258 PDRTVFLTSTANDLTARDFFSFALHVARGMAHVANNKIVHRDVAARNVLISERNVCKVSD 79
Query: 151 FGLARAFGIPIRVYTHEVVT 170
FGL+R G VY E+V+
Sbjct: 78 FGLSRRVGDQNDVY--EIVS 25
>27546
Length = 426
Score = 63.2 bits (152), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 31/107 (28%), Positives = 60/107 (56%), Gaps = 1/107 (0%)
Frame = -1
Query: 50 REISLLKELRHPNIVSLQDVLMQDSRLYLIFEFLSM-DLKKYLDSIPPGQYMDSSLVKVK 108
RE+ +L L HPNI+ + +L + ++++ + D+ ++ P +D + KV
Sbjct: 333 RELEILTRLDHPNIIQIHSILQRGPKIFIFMRYAEKGDMLSHIKKTGP---IDEAQTKV- 166
Query: 109 AQSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLAR 155
+ +Q+ + + + HS + HRDLK +N+L+ + +K+ADFG AR
Sbjct: 165 ---WFFQMAKALQYLHSHDIAHRDLKCENILLSKRLNVKIADFGFAR 34
>26560
Length = 398
Score = 63.2 bits (152), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 37/110 (33%), Positives = 60/110 (54%), Gaps = 4/110 (3%)
Frame = -1
Query: 112 YLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTL 171
Y +++ G+ HSR V++RDLKP N+L+D+ G ++++D GLA F R + V T
Sbjct: 341 YAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGLACDFS-KKRPHA-SVGTH 168
Query: 172 WYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLF----HGDSEIDQL 217
Y +PEVL+ Y + D +S G + +L F G + ID++
Sbjct: 167 GYMAPEVLMKGQSYDSSADWFSFGCMLYKLLKGHSPFRQHNQGQARIDRM 18
>13212
Length = 1067
Score = 62.4 bits (150), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 49/184 (26%), Positives = 78/184 (42%), Gaps = 5/184 (2%)
Frame = -1
Query: 113 LYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLW 172
+++ + F H V+HRD+K N+L+ G +KLADFG++ + + T +
Sbjct: 962 CHEMCMALDFLHRHHVIHRDIKAGNVLLTIDGEVKLADFGVSAKNTQTQQKRDTFIGTPY 783
Query: 173 YRSPEVLLGSARYSTP----VDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPN 228
+ +PEV+L TP DIWS+G E A +P PN
Sbjct: 782 WMAPEVVLCETLKDTPYDFKADIWSLGVTLIEFAQIEP--------------------PN 663
Query: 229 NEVWPEVESLQDYKNTFPKW-KPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALN 287
E+ P ++ +K+ P KP K D ++K L+ DP R + L
Sbjct: 662 KEMHPMRVLIKIHKSDPPTLEKPKKWTKLFK-------DFIAKCLVKDPNLRPTAAELLE 504
Query: 288 HPYF 291
HP+
Sbjct: 503 HPFM 492
>00392
Length = 668
Score = 62.0 bits (149), Expect = 3e-10, Method: Compositional matrix adjust.
Identities = 52/179 (29%), Positives = 89/179 (49%), Gaps = 10/179 (5%)
Frame = +3
Query: 51 EISLLKELRHPNIVSLQDVLMQDSR-----LYLIFEFL-SMDLKKYLDSIPPGQYMDSSL 104
E +LKEL+HPNIV D + + + L+ E + S LK YL
Sbjct: 81 EAEMLKELQHPNIVRFFDYWEEHNHRNRKVIILVTELMTSGTLKTYLKRFKKPN------ 242
Query: 105 VKVKAQSYLYQILQGIVFCHSRR--VLHRDLKPQNLLIDD-KGTIKLADFGLARAFGIPI 161
VK+ +++ Q+L+G+ F H+R V+HRDLK N+ I G++K+ D GLA +
Sbjct: 243 VKI-LKNWCRQVLKGLYFLHTRTPPVIHRDLKCDNIFITGPTGSVKIGDLGLA---TLKN 410
Query: 162 RVYTHEVV-TLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFR 219
+ + V+ T + +PE+ Y VD+++ G E+A+ + + S Q+++
Sbjct: 411 QSFAKSVIGTPEFMAPEMY--EEHYDEAVDVYAFGMCMLEMASSEYPYSECSNAAQIYK 581
>26909
Length = 394
Score = 61.2 bits (147), Expect = 5e-10, Method: Compositional matrix adjust.
Identities = 36/113 (31%), Positives = 52/113 (46%), Gaps = 18/113 (15%)
Frame = +2
Query: 197 IFAELATKKPLFHGDSE---------IDQLFRIFRALGTPNNEVWPEVESLQDYKNTFPK 247
IFAEL T +P+FH E DQL RIF +G P + W ++ + +++
Sbjct: 2 IFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFPQEKDWEDIRRMPEHQQLTKD 181
Query: 248 WKPGS---------LASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYF 291
+K S + H D LL K+L DP KRI+ + A+ PYF
Sbjct: 182 FKRSSYVNCNLMKYMEKHKVKADSKAFHLLQKLLTMDPVKRITSEQAMKDPYF 340
>31489
Length = 329
Score = 59.3 bits (142), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 34/94 (36%), Positives = 57/94 (60%), Gaps = 6/94 (6%)
Frame = +3
Query: 52 ISLLKELRHPNIVSLQDVLM-QDS-----RLYLIFEFLSMDLKKYLDSIPPGQYMDSSLV 105
I +LK +H NI+S++++L +DS ++++F+ + DL + + Y D L
Sbjct: 3 IKILKHFKHDNIISIREILKPKDSYHDFKDIHVVFDLMESDLHRII-------YSDQPLT 161
Query: 106 KVKAQSYLYQILQGIVFCHSRRVLHRDLKPQNLL 139
+ + +LYQIL+G+ + HS V+HRDLKP NLL
Sbjct: 162 EEHIRYFLYQILRGLKYIHSANVVHRDLKPSNLL 263
>14116
Length = 1017
Score = 59.3 bits (142), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 53/215 (24%), Positives = 97/215 (45%), Gaps = 15/215 (6%)
Frame = -1
Query: 5 TKIEKIGEGTYGVVYKGRHKTTGQ----VVAMKKIRLESEEEGVPSTAIREISLLKELRH 60
T E+IG+G +G V +G Q +VA+K + + E + ++E ++K+ H
Sbjct: 627 TMGEEIGKGNFGCVKRGFLTLPEQKGDILVAVKTLHNNNPREIELQSFLQEALIMKDFHH 448
Query: 61 PNIVSLQDVLMQ-DSRLYLIFEFLSM-DLKKYLDSIPPGQYMDSSLVKVKAQ-SYLYQIL 117
N+++L + + D ++ F+ DL Y+ D +K Y I
Sbjct: 447 SNVLTLIGICLNLDDMPLVVLPFMKHGDLLTYIRD-------DQHQPTIKDLIMYGVDIA 289
Query: 118 QGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPE 177
+G+ + + +HRDL +N ++D+ +K+ADFGLAR +Y E + + +
Sbjct: 288 RGMDYLAGLKFVHRDLAARNCMLDEDFHVKVADFGLAR------DIYEKEYYSSENKKAK 127
Query: 178 V--------LLGSARYSTPVDIWSIGTIFAELATK 204
+ L Y + D+WS G + EL T+
Sbjct: 126 LPVKWMALESLEKGNYDSKTDVWSYGVVLWELLTR 22
>07940
Length = 1336
Score = 58.5 bits (140), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 31/95 (32%), Positives = 55/95 (57%), Gaps = 2/95 (2%)
Frame = -3
Query: 111 SYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGI--PIRVYTHEV 168
SY YQ+ +G+ + S++ +HRDL +N+L+ ++ +K+ADFGL R R T
Sbjct: 335 SYAYQVARGMEYLASKQCIHRDLAARNVLVAEEYVLKIADFGLTRNLQQFDYYRKTTDGR 156
Query: 169 VTLWYRSPEVLLGSARYSTPVDIWSIGTIFAELAT 203
+ + + +PE L +Y++ D+WS G + E+ T
Sbjct: 155 LPVKWMAPEALF-DRKYTSKSDVWSYGVLLWEIFT 54
>18401
Length = 463
Score = 57.4 bits (137), Expect = 8e-09, Method: Compositional matrix adjust.
Identities = 50/147 (34%), Positives = 68/147 (46%), Gaps = 22/147 (14%)
Frame = -3
Query: 168 VVTLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALG-- 225
V T YR+PEV+L +S P D+WS+G I EL T LF + L + R LG
Sbjct: 449 VSTRHYRAPEVILELG-WSHPCDVWSVGCIMFELYTGYTLFQTHDNKEHLAMMERILGSL 273
Query: 226 -------TPNNEVW-------PEVESLQDY--KNTFPKWKPGSLASHVK---NLDENGL- 265
T + + PE S+ Y +NT P L +VK N D L
Sbjct: 272 PYRMAKKTKKQKYFHHGRLDVPERSSMARYVRENTKP------LLRYVKDRENKDHQQLF 111
Query: 266 DLLSKMLIYDPAKRISGKMALNHPYFN 292
DL+ K+L Y+ + R S AL HP+F+
Sbjct: 110 DLMKKLLAYEASSRYSLLQALQHPFFS 30
>14477
Length = 493
Score = 56.2 bits (134), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 41/152 (26%), Positives = 79/152 (51%), Gaps = 3/152 (1%)
Frame = -1
Query: 9 KIGEGTYGVVYKGRHKTTGQV--VAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSL 66
K+G G +G V KG + + VA+K ++ + V S I+E ++K++ H +IV L
Sbjct: 469 KLGAGNFGSVMKGVCRLDDREIPVAIKVLKNADLDPSVQSELIKEAEVMKKMDHMHIVRL 290
Query: 67 QDVLMQDSRLYLIFEFLSMD-LKKYLDSIPPGQYMDSSLVKVKAQSYLYQILQGIVFCHS 125
L + + L+ E + L K+L P ++ L ++Q+ QG+ + +
Sbjct: 289 IG-LCEGETMMLVLELAKLGPLNKFL---PKNKH----LPLWNILELMWQVSQGMEYLEA 134
Query: 126 RRVLHRDLKPQNLLIDDKGTIKLADFGLARAF 157
+ +HRDL +N+L+ D+ K++DFG+++
Sbjct: 133 NKFVHRDLAARNILLCDEHFAKISDFGMSKTL 38
>22005
Length = 873
Score = 55.5 bits (132), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 63/242 (26%), Positives = 99/242 (40%), Gaps = 50/242 (20%)
Frame = +1
Query: 10 IGEGTYGVVYK----GRHKTTGQVVAMK------KIRLESEEEGVPSTAIREISLLKELR 59
IG+G +G V K G G+++ K K+ E E + S RE SL+ +
Sbjct: 7 IGQGAFGRVSKLKFLGLASLVGELIPEKRP*LL*KMLKEDASEDLQSDFEREASLMADFD 186
Query: 60 HPNIVSLQDVLMQDSRLYLIFEFLSM-DLKKYLDSIPPGQY-----------MD------ 101
HPNIV L V + L+FEF+S DL +L P Y +D
Sbjct: 187 HPNIVKLLGVCAIGKPMCLLFEFMSKGDLNDFLRLCSPENYNLPVSRSQNLVVDLEDGLR 366
Query: 102 -------------------SSLVKVKAQSYL-YQILQGIVFCHSRRVLHRDLKPQNLLID 141
S ++ K Q Y+ QI G+ + + +HRDL + +
Sbjct: 367 VEVEAEECEKDTQSEDRDCSGMLXTKDQLYISQQISAGMAYLAQKDYVHRDLATRTVXS- 543
Query: 142 DKGTIKLADFGLARAFGIP--IRVYTHEVVTLWYRSPEVLLGSARYSTPVDIWSIGTIFA 199
++DFGLAR+ R + + + + E +L S ++ST D+WS G +
Sbjct: 544 RTT*S*ISDFGLARSVHSVDYYRGSEQDAIPIRWMPLEAILYS-KFSTQSDVWSFGVVLW 720
Query: 200 EL 201
E+
Sbjct: 721 EI 726
>21079
Length = 878
Score = 54.7 bits (130), Expect = 5e-08, Method: Compositional matrix adjust.
Identities = 42/143 (29%), Positives = 73/143 (51%), Gaps = 5/143 (3%)
Frame = +1
Query: 60 HPNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKVKAQSYLYQILQG 119
HP ++ L D + L+ EF+ + + + ++ L + ++ QI G
Sbjct: 1 HPKLLMLWDAFEAPRTMVLVMEFVGA--GELFERVIRDDFV---LTERDCVHFVRQICSG 165
Query: 120 IVFCHSRRVLHRDLKPQNLLI--DDKGTIKLADFGLARAF--GIPIRVYTHEVVTLWYRS 175
+ + H++ +LH DLKP+N+L D+ IK+ DFGLAR + G ++V T + +
Sbjct: 166 VGYMHTQSILHLDLKPENVLCVSDNSNQIKIIDFGLARFYKPGDSLQVLFG---TPEFIA 336
Query: 176 PEVL-LGSARYSTPVDIWSIGTI 197
PEV+ ++T D+WSIG I
Sbjct: 337 PEVVNYDEINFTT--DMWSIGVI 399
>26711
Length = 405
Score = 54.7 bits (130), Expect = 5e-08, Method: Compositional matrix adjust.
Identities = 36/105 (34%), Positives = 54/105 (51%), Gaps = 2/105 (1%)
Frame = -2
Query: 115 QILQGIVFCHSRRVLHRDLKPQNLLI--DDKGTIKLADFGLARAFGIPIRVYTHEVVTLW 172
Q+L + H++ V+H DLKP NLL+ D +++L DFGLAR P + + T
Sbjct: 392 QVLDILQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARKLYPPQETFLNH-GTPG 216
Query: 173 YRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQL 217
+ SPE L ST D+W +G + L + + F DS + L
Sbjct: 215 FTSPEA-LDVKPISTASDVWGVGVLAYILLSGQSPFQADSATESL 84
>28157
Length = 400
Score = 54.3 bits (129), Expect = 6e-08, Method: Compositional matrix adjust.
Identities = 46/131 (35%), Positives = 68/131 (51%), Gaps = 6/131 (4%)
Frame = +3
Query: 30 VAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQDVLMQDSRLYLIFEFL-SMDLK 88
VA+K R+ESE+E + ++E+ L + HPNIV L +D + L+ E+ L
Sbjct: 9 VAVK--RIESEQE--KKSFMQELKQLSRVSHPNIVCLYGAC-RDHPVCLVMEYAEGGSLY 173
Query: 89 KYLD-SIPPGQYMDSSLVKVKAQSYLYQILQGIVFCHS---RRVLHRDLKPQNLLIDDKG 144
L S P QY A ++L Q G+ + H + ++HRDLKP NLL+ G
Sbjct: 174 NVLHGSGPQPQY-----TAAHAMNWLLQCALGVEYLHGMKPKALIHRDLKPPNLLLIQCG 338
Query: 145 T-IKLADFGLA 154
T +K+ DFG A
Sbjct: 339 TKLKICDFGTA 371
>32359
Length = 928
Score = 43.9 bits (102), Expect(2) = 2e-07, Method: Compositional matrix adjust.
Identities = 36/141 (25%), Positives = 64/141 (45%), Gaps = 15/141 (10%)
Frame = -1
Query: 4 YTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNI 63
YT + IG G++GVVY+ + T ++VA+KK+ + + RE+ ++++L H NI
Sbjct: 424 YTDAKVIGNGSFGVVYQAKLVDTSELVAIKKVLQDKRFKN------RELQIMRKLEHQNI 263
Query: 64 VSLQDVLMQDSRLYLIFEFLSMDLKK-------YLDSIPPGQYMDSSLVKVKAQS----- 111
V L+ F F S KK L+ +P Y + Q+
Sbjct: 262 VKLK------------FFFYSSGEKKDEVFLNLVLEYVPETVYRVARHYSKSKQTIPILY 119
Query: 112 ---YLYQILQGIVFCHSRRVL 129
Y+YQ+ + + + HS+ +
Sbjct: 118 IKLYMYQLFRSLAYIHSQACV 56
Score = 28.9 bits (63), Expect(2) = 2e-07, Method: Compositional matrix adjust.
Identities = 11/14 (78%), Positives = 13/14 (92%)
Frame = -3
Query: 128 VLHRDLKPQNLLID 141
V HRD+KPQNLL+D
Sbjct: 62 VCHRDIKPQNLLLD 21
>13840
Length = 446
Score = 52.8 bits (125), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 39/140 (27%), Positives = 62/140 (44%), Gaps = 8/140 (5%)
Frame = -1
Query: 2 EDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHP 61
ED + +IG G YG V K RHK T V+A+K+IR EE + +++ P
Sbjct: 395 EDMQDMGEIGRGNYGTVNKMRHKITSTVMAVKRIRSTVEEREQKQLLMDLDVVMRSNNCP 216
Query: 62 NIVSLQDVLMQDSRLYLIFEFLSMDLKKYL--------DSIPPGQYMDSSLVKVKAQSYL 113
IV L ++ ++ E + L K+ SIP ++ +KA +YL
Sbjct: 215 FIVQFYGALFKEGDCWICMELMETSLDKFYKFVYGEMQSSIPENILGKITVATLKALNYL 36
Query: 114 YQILQGIVFCHSRRVLHRDL 133
+ L R++HRD+
Sbjct: 35 KEEL---------RIIHRDV 3
>00715
Length = 1788
Score = 48.9 bits (115), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 48/179 (26%), Positives = 88/179 (49%), Gaps = 26/179 (14%)
Frame = +1
Query: 58 LRHPNIVSL---QDVLMQDSRLYLIFEFLS-MDLKKYLDSIPPGQYMDSSLVKVKAQSYL 113
LRH N+VS+ + + +L E++ ++L+ L+ Q +DSS+ S
Sbjct: 97 LRHVNVVSILGATSLHRFEDGAWLAMEYVGPLNLQTILND--HQQDIDSSM----RLSLA 258
Query: 114 YQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLA------------RAFGI-- 159
Q+ +G+ + HS ++H DLKP N L+ +++ADFG R G+
Sbjct: 259 LQMARGLHYLHSINIVHLDLKPANCLLTRDLKLRIADFGCCHQLTPTGLDMGEREGGMAG 438
Query: 160 ------PIR-VYTHEVV-TLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHG 210
P++ + +E+ TL YR+PE+L G + S D++S+G ++ T++ + G
Sbjct: 439 NELELTPVQGAWKNELAGTLAYRAPELLKG-LQPSVRSDVYSLGITLWQMCTRQGPYEG 612
>11185
Length = 473
Score = 48.5 bits (114), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 31/109 (28%), Positives = 49/109 (44%), Gaps = 22/109 (20%)
Frame = +1
Query: 115 QILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIR---VYTHEVVTL 171
++ G+ + HS +L DL+P +L+D G +K ADFGL++ G + E
Sbjct: 25 HLVTGLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQ 204
Query: 172 W-------------------YRSPEVLLGSARYSTPVDIWSIGTIFAEL 201
W Y +PEV G A S D+W++G +F E+
Sbjct: 205 WNIQSAEEMMKQVPTSGSPTYMAPEVFQG-AEPSIMSDLWALGCVFYEM 348
>18996
Length = 491
Score = 47.8 bits (112), Expect = 5e-06, Method: Compositional matrix adjust.
Identities = 26/79 (32%), Positives = 47/79 (59%), Gaps = 3/79 (3%)
Frame = +2
Query: 129 LHRDLKPQNLLIDDKGTIKLADFGLAR---AFGIPIRVYTHEVVTLWYRSPEVLLGSARY 185
+HRDL +N+L+D + +K++DFGLA+ A G + ++ WY SPE + + ++
Sbjct: 2 IHRDLAARNILVD-RSCVKISDFGLAQFANADGYYYGISQRDIPIKWY-SPEA-IETCKF 172
Query: 186 STPVDIWSIGTIFAELATK 204
S+ D+WS G E+ ++
Sbjct: 173 SSYSDVWSYGVTLFEMFSR 229
>16003
Length = 926
Score = 47.8 bits (112), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 33/88 (37%), Positives = 46/88 (52%)
Frame = -1
Query: 206 PLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNTFPKWKPGSLASHVKNLDENGL 265
P GD+++DQL +IF LGTP WP V SL DY F + L ++ L
Sbjct: 911 PFLPGDTDLDQLGKIFNMLGTPTETEWPAVTSLPDYIQ-FKHCQKQPLKEIFTAAGDDLL 735
Query: 266 DLLSKMLIYDPAKRISGKMALNHPYFND 293
+LL K+L +P R + AL PYF++
Sbjct: 734 ELLDKLLAMNPLHRCTATQALKMPYFSN 651
>07291
Length = 833
Score = 47.8 bits (112), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 33/143 (23%), Positives = 66/143 (46%), Gaps = 7/143 (4%)
Frame = +1
Query: 115 QILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVT---- 170
QI G+ + +V+HR+L +N ++ + G ++L+D+G+ + P YT +
Sbjct: 73 QIADGMAYLQEVKVVHRNLAARNCIVTEDGRLQLSDYGVTGSL-FPQSYYTADDSPARDL 249
Query: 171 LWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRA---LGTP 227
+ + +PE + + +S+ D+W+ G + EL T+ + D E L + + P
Sbjct: 250 VKWMAPET-IDNFHFSSKSDVWAFGVVLWELLTRGITPYPDVENSSLLPYLKEGHRMKKP 426
Query: 228 NNEVWPEVESLQDYKNTFPKWKP 250
P E + N P+ +P
Sbjct: 427 KQSPEPVYEMMTACWNESPEQRP 495
>01106
Length = 878
Score = 47.0 bits (110), Expect = 8e-06, Method: Compositional matrix adjust.
Identities = 41/150 (27%), Positives = 73/150 (48%), Gaps = 13/150 (8%)
Frame = +3
Query: 4 YTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNI 63
Y I K+G G + V+ T + VA+K ++ + TA+ E+ LLK +R ++
Sbjct: 324 YHVIRKLGWGHFSTVWLCWDLTCKRFVALKVVK---SAQHYTETALDEVKLLKCVRESDV 494
Query: 64 --------VSLQDVL----MQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKVKAQS 111
V L D + + + ++FE L +L L I Y + VK
Sbjct: 495 ADPARAKCVQLLDDFKISGVNGTHVAMVFEVLGYNL---LKLIIRSNYQGIPIHNVKL-- 659
Query: 112 YLYQILQGIVFCHSR-RVLHRDLKPQNLLI 140
+ Q+L+G+ + H++ R++H D+KP+N+LI
Sbjct: 660 IIRQVLEGLSYMHAKCRIIHTDIKPENILI 749
>13078
Length = 773
Score = 46.6 bits (109), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 36/126 (28%), Positives = 55/126 (43%), Gaps = 16/126 (12%)
Frame = -1
Query: 185 YSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNT 244
+S P D+WSIG I EL T LF + L + R LG+ + + + + + +
Sbjct: 746 WSQPCDVWSIGCIMFELYTGYTLFQTHDNKEHLAMMERILGSLPYRMAKKTKKQKYFYHG 567
Query: 245 FPKWKPGSLAS------------HVKNLDENG----LDLLSKMLIYDPAKRISGKMALNH 288
W S A +VK+ D DL+ KML Y+ + R S + A+ H
Sbjct: 566 RLDWDEKSSAGRYVRDNVKPLRRYVKDPDNEDHQQLFDLMDKMLSYEVSTRYSLRQAMRH 387
Query: 289 PYFNDL 294
P+F L
Sbjct: 386 PFFRKL 369
>06358
Length = 1517
Score = 46.2 bits (108), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 71/320 (22%), Positives = 130/320 (40%), Gaps = 29/320 (9%)
Frame = +3
Query: 4 YTKIEKIGEGTYGVVYKGRHKTT---GQVVAMKKIRLES----EEEGVPSTAIREISLLK 56
Y ++ G G V+ K+T V +K ++ + E + + L
Sbjct: 12 YNQVASAGPGLLWKVFAASKKSTKEEASVFVFEKKSVDRYSRRDREAIVEVLRVGVQQLT 191
Query: 57 ELRHPNIVSLQDVLMQDSRLYLIFE----FLSM-DLKKYLDSIP--PGQYMDSSLVKVKA 109
+LRHP I+++ + L ++SR L F F S+ ++ L SI P + D L V+
Sbjct: 192 KLRHPKILAVINPL-EESRETLAFATEPVFASLANVLGDLSSIXTVPKELQDYQLYDVEI 368
Query: 110 QSYLYQILQGIVFCHS-RRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEV 168
+ L Q+ + + F H+ +++HR++ P+ +++ G+ KLA + P
Sbjct: 369 KHGLLQVTEALGFLHNDAKMMHRNVCPEAIMLTKLGSWKLAGYEFCVRSSDPQSTDPSYP 548
Query: 169 VTLW-------------YRSPEVLLGSARYSTPVDIWSIG-TIFAELATKKPLFHGDSEI 214
W + +PE +L + + T D++S+G +++ A KPLF + E+
Sbjct: 549 FYEWRSDIAPVTQPHLDFMAPEYVL-TMQCGTGSDMFSLGLLVYSVFAKGKPLFECNGEL 725
Query: 215 DQLFRIFRALGTPNNEVWPEVESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIY 274
F++ E L+ + + P L HVK L L
Sbjct: 726 SA----FKS----------NAEELRHMRVSLLGVVPEDLRDHVKLL-----------LNI 830
Query: 275 DPAKRISGKMALNHPYFNDL 294
+PA R P+F D+
Sbjct: 831 EPAVRPDAAQLSKVPFFEDV 890
>16708
Length = 1397
Score = 45.8 bits (107), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 47/211 (22%), Positives = 87/211 (41%), Gaps = 15/211 (7%)
Frame = -1
Query: 7 IEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH----PN 62
++ +G+G +G VY+ R +T + A+K L ++ E+ L +
Sbjct: 1388 LQVLGKGVFGKVYEARLLSTHEKAALKTSILCHH-------SLDEVEALGRIEGGFYLAQ 1230
Query: 63 IVSLQDVLMQDSRLYLIFEFLSMD-----LKKYLDSIPPGQYMDSSLVKVKAQSYLYQIL 117
+ + ++ ++ F M Y + P ++ + ++V A Q +
Sbjct: 1229 MFGAWVTCLPFPKMNILLHFYEMGPLCNVYAHYKNKEMPIRWSNPAMVCCIAG----QXV 1062
Query: 118 QGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGI-PIRVYTHEVV-----TL 171
+ H V+H D+K N+L+D G KL D+G+A+ + + P TH T
Sbjct: 1061 CALEHIHELGVVHMDVKADNVLVDAHGNCKLTDYGIAQLYKVYPAPTETHSSGCTNKRTF 882
Query: 172 WYRSPEVLLGSARYSTPVDIWSIGTIFAELA 202
+ R P + S R+S D IGT + L
Sbjct: 881 YTRPPATMTPSERFSEEGD--GIGTDYFRLG 795
>16350
Length = 1108
Score = 45.1 bits (105), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 31/80 (38%), Positives = 42/80 (52%), Gaps = 3/80 (3%)
Frame = +2
Query: 132 DLKPQNLLIDDKGT---IKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSARYSTP 188
D KP+ +++ T +K+AD G A +T ++ T YR EVL+G A Y TP
Sbjct: 305 DNKPECDPVNEICTDFPVKIADLGNAC---WTYHHFTEDIQTRQYRCLEVLIG-AGYGTP 472
Query: 189 VDIWSIGTIFAELATKKPLF 208
DIWS + ELAT LF
Sbjct: 473 ADIWSTACMAFELATGDYLF 532
>36481
Length = 806
Score = 44.7 bits (104), Expect = 4e-05, Method: Compositional matrix adjust.
Identities = 37/138 (26%), Positives = 64/138 (46%), Gaps = 6/138 (4%)
Frame = +2
Query: 11 GEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPN------IV 64
GEGT+G V + + G +A+K I+ + A EI++L++LR + V
Sbjct: 389 GEGTFGKVVQCKDLLKGDDIALKIIK---NVDKYREAAKLEINVLEKLREKDPHAKHMCV 559
Query: 65 SLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKVKAQSYLYQILQGIVFCH 124
+ D + + F L + + +L G Y + +V+ SY Q+ + F H
Sbjct: 560 QMLDWFDYHGHVCISFHMLGLSVFDFLKDNSYGAY---PIEQVRHISY--QLCYAVNFLH 724
Query: 125 SRRVLHRDLKPQNLLIDD 142
++ H DLKP+N+L D
Sbjct: 725 ENQLTHTDLKPENILFVD 778
>20640
Length = 1492
Score = 44.7 bits (104), Expect = 5e-05, Method: Compositional matrix adjust.
Identities = 25/78 (32%), Positives = 43/78 (55%), Gaps = 2/78 (2%)
Frame = +1
Query: 126 RRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIP--IRVYTHEVVTLWYRSPEVLLGSA 183
R +HRDL +N L+ +K++DFGLAR+ R H+ + + + E +L +
Sbjct: 1 RGYVHRDLATRNCLVGHDLVVKISDFGLARSVHSVDYYRGSEHDAIPIRWMPLEAILYN- 177
Query: 184 RYSTPVDIWSIGTIFAEL 201
++ST D+WS G + E+
Sbjct: 178 KFSTQSDVWSFGVVLWEI 231
>05084
Length = 1324
Score = 43.5 bits (101), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 30/95 (31%), Positives = 50/95 (52%), Gaps = 3/95 (3%)
Frame = +2
Query: 210 GDSEIDQLFRIFRALGTPNNEVWPEVE-SLQDYKNTFPKWK--PGSLASHVKNLDENGLD 266
GDS +DQL I + LGTP E E+ + ++K FP+ K P + + E +
Sbjct: 8 GDSGVDQLVEIIKVLGTPTREQIREMNPNYSEFK--FPQIKAHPWTKVFRPRTPPE-AIQ 178
Query: 267 LLSKMLIYDPAKRISGKMALNHPYFNDLDNQIKKM 301
L+S++L Y P+ RI A H +F++L + ++
Sbjct: 179 LVSRLLEYTPSARIQPMEACAHAFFDELRDPASRL 283
>26156
Length = 479
Score = 41.6 bits (96), Expect(2) = 1e-04, Method: Compositional matrix adjust.
Identities = 23/86 (26%), Positives = 43/86 (50%), Gaps = 2/86 (2%)
Frame = -1
Query: 1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLE--SEEEGVPSTAIREISLLKEL 58
+ D+ + IG G+Y V + HK T ++ AMK I+ E +++E + +
Sbjct: 392 LTDFLLLRVIGRGSYAKVLQVEHKRTKRIYAMKVIKKELVNDDEDIDWVQTEKHVFETAT 213
Query: 59 RHPNIVSLQDVLMQDSRLYLIFEFLS 84
+P +V L +SRL+ + EF++
Sbjct: 212 NYPFLVGLHSCFQSESRLFFVIEFVN 135
Score = 21.2 bits (43), Expect(2) = 1e-04, Method: Compositional matrix adjust.
Identities = 9/23 (39%), Positives = 14/23 (60%)
Frame = -3
Query: 112 YLYQILQGIVFCHSRRVLHRDLK 134
Y +I + F H R +++RDLK
Sbjct: 72 YSAEICLALNFLHKRGIVYRDLK 4
>11404
Length = 563
Score = 42.7 bits (99), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 41/139 (29%), Positives = 69/139 (49%), Gaps = 8/139 (5%)
Frame = +1
Query: 10 IGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKEL-RHPN-----I 63
IG+G++G V K T + VA+K I+ ++ + A E+ LL+ + RH I
Sbjct: 163 IGKGSFGQVVKAYDHTDNEQVAIKIIK---NKKPFLNQAQIEVKLLEMMNRHDTDNKYYI 333
Query: 64 VSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKVKAQSYLYQILQGIVFC 123
V L+ M S L L+FE LS +L D + + SL + + Q+ ++F
Sbjct: 334 VRLKRHFMFRSHLCLVFELLSYNL---YDLLRNTNFRGVSLNLTR--KFAQQLCTALLFL 498
Query: 124 HS--RRVLHRDLKPQNLLI 140
+ ++H DLKP+N+L+
Sbjct: 499 ATPEMSIIHCDLKPENILL 555
>12786
Length = 460
Score = 42.4 bits (98), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 34/133 (25%), Positives = 56/133 (42%), Gaps = 21/133 (15%)
Frame = -3
Query: 98 QYMDSSLVKVKAQSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAF 157
Q +D ++K Y ++L+ + H+ V+H DLKP N ++ G +KL DFG+A
Sbjct: 425 QGLDRMMIKF----YWREMLRAVKALHNEGVIHSDLKPANFML-VAGNLKLIDFGIANTL 261
Query: 158 --GIPIRVYTHEVVTLWYRSPEVLLGSA-----------------RYSTPV--DIWSIGT 196
+ V T Y SPE ++ + +Y V D+WS+G
Sbjct: 260 QQDKTSVLKDSRVGTPSYMSPEAIMAACDDSADDSMEEDGHRTKPKYKVGVRSDVWSLGC 81
Query: 197 IFAELATKKPLFH 209
I + + F
Sbjct: 80 ILYNMVYGRTPFQ 42
>37602
Length = 804
Score = 40.8 bits (94), Expect = 8e-04, Method: Compositional matrix adjust.
Identities = 16/37 (43%), Positives = 27/37 (72%)
Frame = -1
Query: 115 QILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADF 151
+ L+G+ + H R +HRD+K N+L+ ++G +KLADF
Sbjct: 195 ETLKGLHYLHRRGKMHRDIKGANILLTEEGDVKLADF 85
Score = 30.4 bits (67), Expect = 1.0, Method: Compositional matrix adjust.
Identities = 12/30 (40%), Positives = 19/30 (63%)
Frame = -2
Query: 1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVV 30
++D+ I+++G GTYG VYK + T G
Sbjct: 512 LDDFELIQRVGSGTYGDVYKAKA*TQGACC 423
>25019
Length = 730
Score = 40.4 bits (93), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 22/63 (34%), Positives = 35/63 (55%)
Frame = +3
Query: 136 QNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSARYSTPVDIWSIG 195
+N+L+D G +KL DFGL + RV T+ Y +PE+L + + VD WS+G
Sbjct: 261 ENVLLDKDGHVKLTDFGLCKEAITGTRVTHTFCGTIEYMAPEILTRTG-HGKAVDWWSLG 437
Query: 196 TIF 198
+ +
Sbjct: 438 SSY 446
>02638
Length = 1490
Score = 40.0 bits (92), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 31/123 (25%), Positives = 49/123 (39%)
Frame = +1
Query: 170 TLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNN 229
T+ + +PEVL G + Y D+WS+G + E+ T +P ++ + L IF+ + +
Sbjct: 25 TIAFMAPEVLRGES-YGRACDVWSVGCVMIEMCTCRPPWNSHDISNHLALIFKIASSVDP 201
Query: 230 EVWPEVESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHP 289
PE N+ DL+ + L D R S K L HP
Sbjct: 202 PPIPE------------------------NMSPPVRDLMLRCLEQDSDFRPSAKDLLMHP 309
Query: 290 YFN 292
F
Sbjct: 310 LFT 318
>17300
Length = 480
Score = 40.0 bits (92), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 25/97 (25%), Positives = 47/97 (48%), Gaps = 16/97 (16%)
Frame = +1
Query: 129 LHRDLKPQNLLIDDKGTIKLADFGLARAF--------------GIPIRVYTHEVVTLWYR 174
+HRDL +N+L+++ K+ADFGL+R IP+R E + YR
Sbjct: 40 VHRDLAARNILVNEILVCKVADFGLSREIESDTTEGAYTTKGGKIPVRWTAPEAIA--YR 213
Query: 175 SPEVLLGSARYSTPVDIWSIGTIFAELAT--KKPLFH 209
++++ D+WS G + E+ + ++P ++
Sbjct: 214 ---------KFTSASDVWSFGVVMWEVMSYGERPYWN 297
>20152
Length = 445
Score = 40.0 bits (92), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 31/120 (25%), Positives = 46/120 (38%)
Frame = +1
Query: 176 PEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEV 235
PE+LLG + + VD+WS+G I L + F ++ + L I
Sbjct: 1 PEILLGDSYDAPAVDVWSLGVILYMLVVGEAPFQEANDSETLTMIM-------------- 138
Query: 236 ESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLD 295
D + P ++ DL+ KML +P R S L HP+ ND D
Sbjct: 139 ----DCRYQIP-----------PHISHKCQDLIEKMLQREPVDRASLPHILAHPWLNDGD 273
>26009
Length = 886
Score = 38.5 bits (88), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 14/33 (42%), Positives = 27/33 (81%)
Frame = +3
Query: 108 KAQSYLYQILQGIVFCHSRRVLHRDLKPQNLLI 140
+A+S + Q++ + F HS++++HRD+KP+N+LI
Sbjct: 714 EAKSVMKQLVSALDFMHSKQLVHRDIKPENVLI 812
>00638
Length = 1595
Score = 38.1 bits (87), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 13/30 (43%), Positives = 23/30 (76%)
Frame = +2
Query: 112 YLYQILQGIVFCHSRRVLHRDLKPQNLLID 141
YLY++++ + FCHS ++HRD+KP L++
Sbjct: 431 YLYELMKALDFCHSMGIMHRDVKPSPPLVN 520
>12672
Length = 773
Score = 37.7 bits (86), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 28/90 (31%), Positives = 44/90 (48%), Gaps = 4/90 (4%)
Frame = +3
Query: 118 QGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFG--LARAFGIPIRVYTHEVV--TLWY 173
GI + + +HRD+K N+L+D + T K+ DF ++ G V VV T Y
Sbjct: 24 SGIQYLNDNGHVHRDIKTANILLDSEYTAKVGDFATVVSAPSGEGKTVQNASVVIGTAAY 203
Query: 174 RSPEVLLGSARYSTPVDIWSIGTIFAELAT 203
+PE + ST +D +S G + E+ T
Sbjct: 204 LAPEAI--HFDVSTKLDSYSFGVVLLEVIT 287
>00394
Length = 548
Score = 37.7 bits (86), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 21/60 (35%), Positives = 31/60 (51%)
Frame = -2
Query: 9 KIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQD 68
+IG G++ VYKG G VA +++ + + E +LKEL+HPNIV D
Sbjct: 277 EIGRGSFKTVYKGLDTELGVAVAWCELQDKKWNKAERQRFKEEAEMLKELQHPNIVRFFD 98
>07836
Length = 1478
Score = 37.4 bits (85), Expect = 0.007, Method: Compositional matrix adjust.
Identities = 41/139 (29%), Positives = 68/139 (48%), Gaps = 11/139 (7%)
Frame = -1
Query: 27 GQVVAMKKIRLESEEEGVPSTAIREISLLKE--LRHPNIVSLQDVLMQDS----RLYLIF 80
G+ VA+K I +EE ++ RE L + LRH NI+ ++ + +L+LI
Sbjct: 1478 GENVAVK-IFFTTEE----ASWFRETELYQTVLLRHENILGFIAADIKGTGSWTQLFLIT 1314
Query: 81 EFL-SMDLKKYLDSIPPGQYMDSSLVKVKAQSYLYQILQGIVFCHSRR----VLHRDLKP 135
++ + L YL S + +DSS + A S + + + R + HRD+K
Sbjct: 1313 DYHENGSLHDYLLS----RVLDSSEMLALAHSAICGLAHLHIEIFGTRGKPAIAHRDIKS 1146
Query: 136 QNLLIDDKGTIKLADFGLA 154
+N+L+ GT +AD GLA
Sbjct: 1145 KNILVKKNGTCCIADLGLA 1089
>15549
Length = 470
Score = 36.2 bits (82), Expect = 0.015, Method: Compositional matrix adjust.
Identities = 14/39 (35%), Positives = 28/39 (71%)
Frame = -1
Query: 2 EDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESE 40
+++ IE++G+G YG+V++ ++K Q A+K+I L S+
Sbjct: 218 DEFECIEQMGKGGYGIVFRAKNKVDEQEYAVKRIALPSD 102
>31789
Length = 676
Score = 36.2 bits (82), Expect = 0.017, Method: Compositional matrix adjust.
Identities = 33/119 (27%), Positives = 55/119 (46%), Gaps = 7/119 (5%)
Frame = +2
Query: 9 KIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQD 68
+IG G++ VYKG G VA +++ + + E +LKEL+HPNIV D
Sbjct: 341 EIGRGSFKTVYKGLDTELGVAVAWCELQDKKWNKTERQRFKEEAEMLKELQHPNIVRFFD 520
Query: 69 VLMQDSR-----LYLIFEFL-SMDLKKYLDSIPPGQYMDSSLVKVKA-QSYLYQILQGI 120
+ + + L+ E + S LK YL + +K +++ QIL+G+
Sbjct: 521 YWEEHNHRNRKVIILVTELMTSGTLKTYLKRFKK--------INLKVLKNWCRQILKGL 673
>21800
Length = 855
Score = 35.8 bits (81), Expect = 0.020, Method: Compositional matrix adjust.
Identities = 36/118 (30%), Positives = 59/118 (50%), Gaps = 15/118 (12%)
Frame = +2
Query: 47 TAIREISLLKELRHPN--------IVSLQDVL----MQDSRLYLIFEFLSMDLKKYLDSI 94
TA+ EI LLK +R+ + V L D + + + ++FE L +L K I
Sbjct: 431 TALDEIKLLKCVRNSDETDPAREKSVQLLDDFKISGVNGTHVCMVFEVLGYNLLKL---I 601
Query: 95 PPGQYMDSSLVKVKAQSYLYQILQGIVFCHSR-RVLHRDLKPQNLLI--DDKGTIKLA 149
Y + VK + Q+L+G+ + H++ ++H D+KP+N+LI DD KLA
Sbjct: 602 IRSNYQGIPVHNVKL--IIRQVLEGLNYLHAKCNIIHTDIKPENILICVDDNYIRKLA 769
>20773
Length = 391
Score = 34.3 bits (77), Expect = 0.059, Method: Compositional matrix adjust.
Identities = 11/35 (31%), Positives = 25/35 (71%)
Frame = -1
Query: 256 HVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPY 290
H + ++ +L+ ++L YDP++R++ +AL+HP+
Sbjct: 334 HTTVVTQHFYNLVQRLLTYDPSQRLTPDLALSHPF 230
>17644
Length = 463
Score = 33.9 bits (76), Expect = 0.089, Method: Compositional matrix adjust.
Identities = 11/35 (31%), Positives = 24/35 (68%)
Frame = +3
Query: 256 HVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPY 290
H + ++ BL+ ++L YDP++R++ +AL+HP+
Sbjct: 57 HTTVVTQHFYBLVQRLLTYDPSQRLTPDLALSHPF 161
>18481
Length = 437
Score = 32.7 bits (73), Expect = 0.16, Method: Compositional matrix adjust.
Identities = 16/46 (34%), Positives = 26/46 (56%), Gaps = 3/46 (6%)
Frame = -1
Query: 115 QILQGIVFCHSRRVLHRDLKPQNLLID---DKGTIKLADFGLARAF 157
Q+L + F H + +HRDLKP N L+ + + DFGL++ +
Sbjct: 173 QLLSRLEFIHQKCFIHRDLKPDNFLMGLGRHCHRLYIIDFGLSKRY 36
>32357
Length = 625
Score = 32.7 bits (73), Expect = 0.17, Method: Compositional matrix adjust.
Identities = 14/30 (46%), Positives = 22/30 (73%)
Frame = -2
Query: 4 YTKIEKIGEGTYGVVYKGRHKTTGQVVAMK 33
Y ++KIG G++G +Y G H T+G+ VA+K
Sbjct: 432 YRLMKKIGSGSFGEIYLGVHNTSGEEVAVK 343
>38560
Length = 479
Score = 32.7 bits (73), Expect = 0.20, Method: Compositional matrix adjust.
Identities = 31/121 (25%), Positives = 48/121 (39%), Gaps = 1/121 (0%)
Frame = -3
Query: 173 YRSPEVLLGSARYSTPVDIWSIGT-IFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEV 231
Y +PE++ G + DIWS+G ++A L P D + L
Sbjct: 387 YAAPELISGLEYLGSEADIWSMGVLLYALLCGYLPF--DDEKXSHL-------------- 256
Query: 232 WPEVESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYF 291
+ Q K+ P+W L E+ LL ML DP+ RI+ + L+H +
Sbjct: 255 ---*QKNQKRKDEVPEW-----------LSEDTTKLLEGMLQTDPSHRITIRRLLDHHWL 118
Query: 292 N 292
N
Sbjct: 117 N 115
>35032
Length = 465
Score = 32.0 bits (71), Expect = 0.29, Method: Compositional matrix adjust.
Identities = 12/27 (44%), Positives = 19/27 (70%)
Frame = +3
Query: 265 LDLLSKMLIYDPAKRISGKMALNHPYF 291
DL+ ++L YDP+KR++ AL HP+
Sbjct: 144 FDLVKRLLNYDPSKRLTPXXALAHPFL 224
>15931
Length = 447
Score = 31.6 bits (70), Expect = 0.42, Method: Compositional matrix adjust.
Identities = 13/30 (43%), Positives = 19/30 (63%)
Frame = +1
Query: 265 LDLLSKMLIYDPAKRISGKMALNHPYFNDL 294
DL+ KML Y+ + R S + A+ HP+F L
Sbjct: 76 FDLMDKMLSYEVSTRYSLRQAMRHPFFRKL 165
>00832
Length = 1465
Score = 28.9 bits (63), Expect = 2.4, Method: Compositional matrix adjust.
Identities = 20/65 (30%), Positives = 35/65 (53%), Gaps = 1/65 (1%)
Frame = +3
Query: 64 VSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDS-SLVKVKAQSYLYQILQGIVF 122
V ++D L QD+ Y + + +++++ L GQ + + LV VKAQ + + QG+V
Sbjct: 258 VDVEDALCQDAHAYGSEQLMRVEMQEML-----GQQLTTRDLVPVKAQLHSRGLFQGVVL 422
Query: 123 CHSRR 127
RR
Sbjct: 423 EEFRR 437
>21210
Length = 518
Score = 28.5 bits (62), Expect = 3.3, Method: Compositional matrix adjust.
Identities = 19/57 (33%), Positives = 27/57 (47%), Gaps = 4/57 (7%)
Frame = +3
Query: 173 YRSPEVL---LGSARYSTPVDIWSIGTIFAELATKK-PLFHGDSEIDQLFRIFRALG 225
Y +PE + S Y D+WS+G ELAT + P S DQL ++ R +
Sbjct: 18 YMAPERIDPRASSHGYDVRSDVWSLGITLMELATGRFPYRKWVSIFDQLQQVVRGVA 188
>13305
Length = 549
Score = 27.7 bits (60), Expect = 5.8, Method: Compositional matrix adjust.
Identities = 11/38 (28%), Positives = 19/38 (50%)
Frame = +2
Query: 185 YSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFR 222
Y+T D+WS G + E+ T + ++ QLF +
Sbjct: 56 YTTQSDVWSFGVVLWEIFTLGGTPYSSTDTQQLFAFLK 169
>17516
Length = 453
Score = 27.7 bits (60), Expect = 6.1, Method: Compositional matrix adjust.
Identities = 12/29 (41%), Positives = 17/29 (58%)
Frame = -3
Query: 173 YRSPEVLLGSARYSTPVDIWSIGTIFAEL 201
Y +PEVLL +Y D++S+ I EL
Sbjct: 421 YMAPEVLLQKGQYDMKADVYSLAIILWEL 335
>17806
Length = 433
Score = 27.3 bits (59), Expect = 8.5, Method: Compositional matrix adjust.
Identities = 16/51 (31%), Positives = 29/51 (56%), Gaps = 1/51 (1%)
Frame = +1
Query: 51 EISLLKELRHPNIVSLQDVLMQDSRLYLIFEFLSM-DLKKYLDSIPPGQYM 100
E++ +EL HPNIV L + + + ++ E ++ +LK+YL + Q M
Sbjct: 208 EVAPFRELDHPNIVRLLGQCTEMNPMLMLMECAALGNLKQYLRNHRHQQAM 360
>26052
Length = 562
Score = 26.9 bits (58), Expect = 9.1, Method: Compositional matrix adjust.
Identities = 11/27 (40%), Positives = 19/27 (70%)
Frame = -1
Query: 10 IGEGTYGVVYKGRHKTTGQVVAMKKIR 36
+G G++G V +HK TG+ +A+K I+
Sbjct: 367 LGVGSFGKVMALQHKDTGETLAVKNIQ 287
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000379263 | hsapiens_gene_ensembl | Tektin-3.
[Source:Uniprot/SWISSPROT;Acc:Q9BXF9]
(490 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
03948 397 e-111
16615 347 8e-96
14949 180 1e-45
33456 134 7e-32
35150 118 5e-27
36475 67 2e-11
31693 62 5e-10
>03948
Length = 2007
Score = 397 bits (1020), Expect = e-111, Method: Compositional matrix adjust.
Identities = 198/393 (50%), Positives = 268/393 (68%)
Frame = +1
Query: 89 TFFTRYTPDDWYRSNLTNYQESNTSRHNSEKLRVDTSRLIQDKYQQTRKTQADTTQNLGE 148
+ ++RY+P+DW SN NY S+ R +E+LR D R +++ +TR Q D T+ LGE
Sbjct: 16 SVYSRYSPNDWNLSNSMNYSLSDKERSFAERLRADAWRAVKETDARTRNRQNDVTKRLGE 195
Query: 149 RVNDIGFWKSEIIHELDEMIGETNALTDVKKRLERALMETEAPLQVARECLFHREKRMGI 208
RV DI FWK+E+ E++ M E L + K+ E+AL +T PL +A ECL +REKR GI
Sbjct: 196 RVYDIXFWKTELNSEVNAMATEIENLKEYKRTCEKALADTANPLHIAEECLMNREKRQGI 375
Query: 209 DLVHDEVEAQLLTEVDTILCCQERMKLHLDKAIAQLAANRASQHELEKDLSDKQTAYRID 268
DLV+D+VE L+ EVD I CQ RMK LDKA QL NRA+QH LE D DK A +D
Sbjct: 376 DLVNDDVEKSLVKEVDIIKRCQARMKKVLDKAYVQLKMNRAAQHALEIDAKDKHHAQGLD 555
Query: 269 DKCHHLRNTSDGVGYFRGVERVDATVSVPESWAKFTDDNILRSQSERAASAKLRDDIENL 328
D+ +RN+S GVGY G+E +D T+++PESWA++T +NI RSQ ERA+S +LR +I++
Sbjct: 556 DRMQQMRNSSAGVGYIPGIESIDNTLTIPESWARYTQENIARSQKERASSERLRGEIDST 735
Query: 329 LVVTANEMWNQFNKVNLSFTNRIAETADAKNKIQTHLAKTLQEIFQTEMTIESIKKAIKD 388
L ANEMWN FN VN SF R+ ET DA+NK+Q HL +T+QEIF E I ++KAI+D
Sbjct: 736 LRHCANEMWNNFNAVNNSFNTRVRETTDARNKLQAHLQRTMQEIFDMERNINLLRKAIQD 915
Query: 389 KTAFLKVAQTRLDERTRRPNIELCRDMAQLRLVNEVHEVDDTIQTLQQRLRDAEDTLQSL 448
K +KVAQTRLDERTRR N+ELC D L EV E+ ++++ L++RL+ +E +L L
Sbjct: 916 KENPMKVAQTRLDERTRRINVELCNDPVMKSLQREVAEIRESVRLLKERLKSSELSLARL 1095
Query: 449 VHIKATLEYDLAVKANSLYIDQEKCMSMRKSYP 481
+ K+TLE+D++VK NSL ID CM MRK +P
Sbjct: 1096MKTKSTLEHDISVKENSLRIDNSFCMGMRKGFP 1194
>16615
Length = 1307
Score = 347 bits (889), Expect = 8e-96, Method: Compositional matrix adjust.
Identities = 194/422 (45%), Positives = 267/422 (63%), Gaps = 28/422 (6%)
Frame = -3
Query: 52 PSTYYKVAS-NSPSVAPYCTRSQRVSE-NTMLPFVSNRT--------------------- 88
PS +++A +SPSV + + E + +LP+V+++T
Sbjct: 1272 PSDNFRMAYYDSPSVVRTRSATPMTPEMSKILPYVTDKTISRHLGSYGKSMDLGHARNYF 1093
Query: 89 -----TFFTRYTPDDWYRSNLTNYQESNTSRHNSEKLRVDTSRLIQDKYQQTRKTQADTT 143
T ++RY P+DW SN NY S+ R +E+LR D R +++ +TR Q D T
Sbjct: 1092 NPAMRTVYSRYNPNDWSLSNSMNYSLSDKERSFAERLRADAWRAVKETDARTRNRQNDVT 913
Query: 144 QNLGERVNDIGFWKSEIIHELDEMIGETNALTDVKKRLERALMETEAPLQVARECLFHRE 203
+ LGERV DI FWK+E+ E++ M E L + K+ E+AL +T PL +A ECL HRE
Sbjct: 912 KRLGERVYDISFWKTELNSEVNAMATEIENLKEYKRTCEKALADTANPLHIAEECLMHRE 733
Query: 204 KRMGIDLVHDEVEAQLLTEVDTILCCQERMKLHLDKAIAQLAANRASQHELEKDLSDKQT 263
KR GIDLV+D+VE L+ EVD I CQ +MK LDKA QL NRA+QH LE D DK
Sbjct: 732 KRQGIDLVNDDVEKSLVKEVDVIKKCQAKMKKVLDKAYVQLKMNRAAQHALEIDAKDKHH 553
Query: 264 AYRIDDKCHHLRNTSDGVGYFRGVERVDATVSVPESWAKFTDDNILRSQSERAASAKLRD 323
A +DD+ LRN+S GVGY G+E +D T+++PESWA++T +NI RSQ ERAAS +LR
Sbjct: 552 AQGLDDRMQQLRNSSAGVGYIPGIENIDNTLTIPESWARYTQENIARSQKERAASERLRG 373
Query: 324 DIENLLVVTANEMWNQFNKVNLSFTNRIAETADAKNKIQTHLAKTLQEIFQTEMTIESIK 383
+I++ L ANEMWN FN VN +F RI E+ DA+NK+Q HL KT+QEIF E I+ ++
Sbjct: 372 EIDSTLRQCANEMWNNFNAVNNAFNTRIRESNDARNKLQAHLQKTMQEIFDMERNIDLLR 193
Query: 384 KAIKDKTAFLKVAQTRLDERTRRPNIELCRDMAQLRLVNEVHEVDDTIQTLQQRLRDAED 443
KAI+DK +KVAQTRLDERTRR N+ELC D L EV E+ ++++ L++RL+ +E
Sbjct: 192 KAIQDKENPMKVAQTRLDERTRRINVELCNDPVMKSLQREVAEIRESVRLLKERLKSSEL 13
Query: 444 TL 445
+L
Sbjct: 12 SL 7
>14949
Length = 465
Score = 180 bits (457), Expect = 1e-45, Method: Compositional matrix adjust.
Identities = 82/151 (54%), Positives = 112/151 (74%)
Frame = -3
Query: 237 LDKAIAQLAANRASQHELEKDLSDKQTAYRIDDKCHHLRNTSDGVGYFRGVERVDATVSV 296
++KA QL RA+QHELEKD DKQ A +D CH +RN+S G+ ++ GV R D TVSV
Sbjct: 454 IEKANVQLGLGRAAQHELEKDSIDKQIAESMDTSCHGIRNSSHGIAFYNGVYRTDNTVSV 275
Query: 297 PESWAKFTDDNILRSQSERAASAKLRDDIENLLVVTANEMWNQFNKVNLSFTNRIAETAD 356
PE+WA+F++DN+ RSQSERAAS ++R++IE +L +NEMWNQ+N N++ RI ET D
Sbjct: 274 PETWARFSNDNVQRSQSERAASKQMRNEIETVLNACSNEMWNQWNAANVALNQRIQETTD 95
Query: 357 AKNKIQTHLAKTLQEIFQTEMTIESIKKAIK 387
+N++QTHL+K LQEIF E IE +KK+I+
Sbjct: 94 TRNRLQTHLSKVLQEIFDMEKNIELLKKSIQ 2
>33456
Length = 677
Score = 134 bits (338), Expect = 7e-32, Method: Compositional matrix adjust.
Identities = 76/202 (37%), Positives = 116/202 (57%), Gaps = 6/202 (2%)
Frame = +3
Query: 93 RYTPDDWYRSNLTNYQESNTSRHNSEKLRVDTSRLIQDKYQQTRKTQADTTQNLGERVND 152
+Y P +W+ SN + Y +S R +E++R ++ R + T KTQAD T+ L ER D
Sbjct: 66 KYNPSEWHESNYSKYYQSFVDRDQAERVRHESKRTSNETEATTNKTQADVTKKLAERCKD 245
Query: 153 IGFWKSEIIHELDEMIGETNALTDVKKRLERALMETEAPLQVARECLFHREKRMGIDLVH 212
I FWK+E+ E+ ++I ET+ L KKRLE AL TE PL ++ + L R++R+G+DLV
Sbjct: 246 IQFWKAEVEREIRDVIDETDLLLAQKKRLENALRATEVPLHISTDNLNCRQRRLGVDLVQ 425
Query: 213 DEVEAQLLTEVDTILCCQERMKLHLDKAIAQLAANRASQHELEKDLSDKQTAYRIDDKCH 272
D+VE LL EV I ++ ++ + ++ Q+ NR ++ LE D SDK+ + ID C
Sbjct: 426 DDVEISLLKEVXIINNVRDLLQNTIAQSEKQIRLNRDAKQNLEMDWSDKKESLEIDTSCG 605
Query: 273 HLRNT------SDGVGYFRGVE 288
LRN DG F ++
Sbjct: 606 VLRNHHTNKQFHDGAAKFEEIQ 671
>35150
Length = 410
Score = 118 bits (296), Expect = 5e-27, Method: Compositional matrix adjust.
Identities = 59/124 (47%), Positives = 84/124 (67%)
Frame = +2
Query: 356 DAKNKIQTHLAKTLQEIFQTEMTIESIKKAIKDKTAFLKVAQTRLDERTRRPNIELCRDM 415
D K K++ HL K + +I + E I ++KAI DK A +K+A TRLD RT RPN+ELCRD
Sbjct: 5 DTKGKLEDHLNKIIGQIKEIEENISRLQKAIADKEAPMKLAHTRLDTRTNRPNVELCRDA 184
Query: 416 AQLRLVNEVHEVDDTIQTLQQRLRDAEDTLQSLVHIKATLEYDLAVKANSLYIDQEKCMS 475
Q R + EV E++ ++ LQ RL D +D+L+ L + LE D+ VK+N+L+ID+ +CM
Sbjct: 185 VQYRPIGEVGELECSLAQLQSRLADTQDSLKGLTRNQLDLEDDIQVKSNTLFIDEVECMG 364
Query: 476 MRKS 479
MRKS
Sbjct: 365 MRKS 376
>36475
Length = 841
Score = 67.0 bits (162), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 29/72 (40%), Positives = 53/72 (73%)
Frame = +3
Query: 418 LRLVNEVHEVDDTIQTLQQRLRDAEDTLQSLVHIKATLEYDLAVKANSLYIDQEKCMSMR 477
RLV EV+E+ +I L+ +L A+++L+ L + +LE +++VK NS++ID++KCM++R
Sbjct: 207 FRLVGEVNEICQSIDALKNQLNQAQNSLKDLQDNRMSLEKEISVKKNSIFIDRDKCMTVR 386
Query: 478 KSYPNTLRLVGF 489
YP+T++L G+
Sbjct: 387 TRYPSTVKLQGY 422
>31693
Length = 851
Score = 62.0 bits (149), Expect = 5e-10, Method: Compositional matrix adjust.
Identities = 29/54 (53%), Positives = 40/54 (74%)
Frame = -2
Query: 393 LKVAQTRLDERTRRPNIELCRDMAQLRLVNEVHEVDDTIQTLQQRLRDAEDTLQ 446
+KVAQTRL+ RT RPN+ELCRD Q LV EV+E+ +I L+ +L AE++L+
Sbjct: 604 MKVAQTRLNSRTYRPNVELCRDPVQYALVGEVNEICQSIDALKNQLNQAENSLK 443
Score = 54.3 bits (129), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 43/139 (30%), Positives = 64/139 (46%), Gaps = 13/139 (9%)
Frame = -1
Query: 364 HLAKTLQEIFQTEMTIESIKKAIK----------DKTAFLKVAQTR---LDERTRRPNIE 410
+L K EI Q E I+S+K AI+ D F + R RT P
Sbjct: 692 NLKKVCGEIAQQEKNIDSLKAAIRAKEDPHEGGSDTPQFTNLPAQRGAVQGPRTVCPGG* 513
Query: 411 LCRDMAQLRLVNEVHEVDDTIQTLQQRLRDAEDTLQSLVHIKATLEYDLAVKANSLYIDQ 470
RD+ R E E + QSL + +LE +++VK NS++ID+
Sbjct: 512 GERDLPVYRRPQEPAE-------------PGGELAQSLQDNRMSLEKEISVKKNSIFIDR 372
Query: 471 EKCMSMRKSYPNTLRLVGF 489
+KCM++R YP+T++L GF
Sbjct: 371 DKCMTVRTRYPSTVKLQGF 315
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000379264 | hsapiens_gene_ensembl | Tektin-3.
[Source:Uniprot/SWISSPROT;Acc:Q9BXF9]
(490 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
03948 397 e-111
16615 347 8e-96
14949 180 1e-45
33456 134 7e-32
35150 118 5e-27
36475 67 2e-11
31693 62 5e-10
>03948
Length = 2007
Score = 397 bits (1020), Expect = e-111, Method: Compositional matrix adjust.
Identities = 198/393 (50%), Positives = 268/393 (68%)
Frame = +1
Query: 89 TFFTRYTPDDWYRSNLTNYQESNTSRHNSEKLRVDTSRLIQDKYQQTRKTQADTTQNLGE 148
+ ++RY+P+DW SN NY S+ R +E+LR D R +++ +TR Q D T+ LGE
Sbjct: 16 SVYSRYSPNDWNLSNSMNYSLSDKERSFAERLRADAWRAVKETDARTRNRQNDVTKRLGE 195
Query: 149 RVNDIGFWKSEIIHELDEMIGETNALTDVKKRLERALMETEAPLQVARECLFHREKRMGI 208
RV DI FWK+E+ E++ M E L + K+ E+AL +T PL +A ECL +REKR GI
Sbjct: 196 RVYDIXFWKTELNSEVNAMATEIENLKEYKRTCEKALADTANPLHIAEECLMNREKRQGI 375
Query: 209 DLVHDEVEAQLLTEVDTILCCQERMKLHLDKAIAQLAANRASQHELEKDLSDKQTAYRID 268
DLV+D+VE L+ EVD I CQ RMK LDKA QL NRA+QH LE D DK A +D
Sbjct: 376 DLVNDDVEKSLVKEVDIIKRCQARMKKVLDKAYVQLKMNRAAQHALEIDAKDKHHAQGLD 555
Query: 269 DKCHHLRNTSDGVGYFRGVERVDATVSVPESWAKFTDDNILRSQSERAASAKLRDDIENL 328
D+ +RN+S GVGY G+E +D T+++PESWA++T +NI RSQ ERA+S +LR +I++
Sbjct: 556 DRMQQMRNSSAGVGYIPGIESIDNTLTIPESWARYTQENIARSQKERASSERLRGEIDST 735
Query: 329 LVVTANEMWNQFNKVNLSFTNRIAETADAKNKIQTHLAKTLQEIFQTEMTIESIKKAIKD 388
L ANEMWN FN VN SF R+ ET DA+NK+Q HL +T+QEIF E I ++KAI+D
Sbjct: 736 LRHCANEMWNNFNAVNNSFNTRVRETTDARNKLQAHLQRTMQEIFDMERNINLLRKAIQD 915
Query: 389 KTAFLKVAQTRLDERTRRPNIELCRDMAQLRLVNEVHEVDDTIQTLQQRLRDAEDTLQSL 448
K +KVAQTRLDERTRR N+ELC D L EV E+ ++++ L++RL+ +E +L L
Sbjct: 916 KENPMKVAQTRLDERTRRINVELCNDPVMKSLQREVAEIRESVRLLKERLKSSELSLARL 1095
Query: 449 VHIKATLEYDLAVKANSLYIDQEKCMSMRKSYP 481
+ K+TLE+D++VK NSL ID CM MRK +P
Sbjct: 1096MKTKSTLEHDISVKENSLRIDNSFCMGMRKGFP 1194
>16615
Length = 1307
Score = 347 bits (889), Expect = 8e-96, Method: Compositional matrix adjust.
Identities = 194/422 (45%), Positives = 267/422 (63%), Gaps = 28/422 (6%)
Frame = -3
Query: 52 PSTYYKVAS-NSPSVAPYCTRSQRVSE-NTMLPFVSNRT--------------------- 88
PS +++A +SPSV + + E + +LP+V+++T
Sbjct: 1272 PSDNFRMAYYDSPSVVRTRSATPMTPEMSKILPYVTDKTISRHLGSYGKSMDLGHARNYF 1093
Query: 89 -----TFFTRYTPDDWYRSNLTNYQESNTSRHNSEKLRVDTSRLIQDKYQQTRKTQADTT 143
T ++RY P+DW SN NY S+ R +E+LR D R +++ +TR Q D T
Sbjct: 1092 NPAMRTVYSRYNPNDWSLSNSMNYSLSDKERSFAERLRADAWRAVKETDARTRNRQNDVT 913
Query: 144 QNLGERVNDIGFWKSEIIHELDEMIGETNALTDVKKRLERALMETEAPLQVARECLFHRE 203
+ LGERV DI FWK+E+ E++ M E L + K+ E+AL +T PL +A ECL HRE
Sbjct: 912 KRLGERVYDISFWKTELNSEVNAMATEIENLKEYKRTCEKALADTANPLHIAEECLMHRE 733
Query: 204 KRMGIDLVHDEVEAQLLTEVDTILCCQERMKLHLDKAIAQLAANRASQHELEKDLSDKQT 263
KR GIDLV+D+VE L+ EVD I CQ +MK LDKA QL NRA+QH LE D DK
Sbjct: 732 KRQGIDLVNDDVEKSLVKEVDVIKKCQAKMKKVLDKAYVQLKMNRAAQHALEIDAKDKHH 553
Query: 264 AYRIDDKCHHLRNTSDGVGYFRGVERVDATVSVPESWAKFTDDNILRSQSERAASAKLRD 323
A +DD+ LRN+S GVGY G+E +D T+++PESWA++T +NI RSQ ERAAS +LR
Sbjct: 552 AQGLDDRMQQLRNSSAGVGYIPGIENIDNTLTIPESWARYTQENIARSQKERAASERLRG 373
Query: 324 DIENLLVVTANEMWNQFNKVNLSFTNRIAETADAKNKIQTHLAKTLQEIFQTEMTIESIK 383
+I++ L ANEMWN FN VN +F RI E+ DA+NK+Q HL KT+QEIF E I+ ++
Sbjct: 372 EIDSTLRQCANEMWNNFNAVNNAFNTRIRESNDARNKLQAHLQKTMQEIFDMERNIDLLR 193
Query: 384 KAIKDKTAFLKVAQTRLDERTRRPNIELCRDMAQLRLVNEVHEVDDTIQTLQQRLRDAED 443
KAI+DK +KVAQTRLDERTRR N+ELC D L EV E+ ++++ L++RL+ +E
Sbjct: 192 KAIQDKENPMKVAQTRLDERTRRINVELCNDPVMKSLQREVAEIRESVRLLKERLKSSEL 13
Query: 444 TL 445
+L
Sbjct: 12 SL 7
>14949
Length = 465
Score = 180 bits (457), Expect = 1e-45, Method: Compositional matrix adjust.
Identities = 82/151 (54%), Positives = 112/151 (74%)
Frame = -3
Query: 237 LDKAIAQLAANRASQHELEKDLSDKQTAYRIDDKCHHLRNTSDGVGYFRGVERVDATVSV 296
++KA QL RA+QHELEKD DKQ A +D CH +RN+S G+ ++ GV R D TVSV
Sbjct: 454 IEKANVQLGLGRAAQHELEKDSIDKQIAESMDTSCHGIRNSSHGIAFYNGVYRTDNTVSV 275
Query: 297 PESWAKFTDDNILRSQSERAASAKLRDDIENLLVVTANEMWNQFNKVNLSFTNRIAETAD 356
PE+WA+F++DN+ RSQSERAAS ++R++IE +L +NEMWNQ+N N++ RI ET D
Sbjct: 274 PETWARFSNDNVQRSQSERAASKQMRNEIETVLNACSNEMWNQWNAANVALNQRIQETTD 95
Query: 357 AKNKIQTHLAKTLQEIFQTEMTIESIKKAIK 387
+N++QTHL+K LQEIF E IE +KK+I+
Sbjct: 94 TRNRLQTHLSKVLQEIFDMEKNIELLKKSIQ 2
>33456
Length = 677
Score = 134 bits (338), Expect = 7e-32, Method: Compositional matrix adjust.
Identities = 76/202 (37%), Positives = 116/202 (57%), Gaps = 6/202 (2%)
Frame = +3
Query: 93 RYTPDDWYRSNLTNYQESNTSRHNSEKLRVDTSRLIQDKYQQTRKTQADTTQNLGERVND 152
+Y P +W+ SN + Y +S R +E++R ++ R + T KTQAD T+ L ER D
Sbjct: 66 KYNPSEWHESNYSKYYQSFVDRDQAERVRHESKRTSNETEATTNKTQADVTKKLAERCKD 245
Query: 153 IGFWKSEIIHELDEMIGETNALTDVKKRLERALMETEAPLQVARECLFHREKRMGIDLVH 212
I FWK+E+ E+ ++I ET+ L KKRLE AL TE PL ++ + L R++R+G+DLV
Sbjct: 246 IQFWKAEVEREIRDVIDETDLLLAQKKRLENALRATEVPLHISTDNLNCRQRRLGVDLVQ 425
Query: 213 DEVEAQLLTEVDTILCCQERMKLHLDKAIAQLAANRASQHELEKDLSDKQTAYRIDDKCH 272
D+VE LL EV I ++ ++ + ++ Q+ NR ++ LE D SDK+ + ID C
Sbjct: 426 DDVEISLLKEVXIINNVRDLLQNTIAQSEKQIRLNRDAKQNLEMDWSDKKESLEIDTSCG 605
Query: 273 HLRNT------SDGVGYFRGVE 288
LRN DG F ++
Sbjct: 606 VLRNHHTNKQFHDGAAKFEEIQ 671
>35150
Length = 410
Score = 118 bits (296), Expect = 5e-27, Method: Compositional matrix adjust.
Identities = 59/124 (47%), Positives = 84/124 (67%)
Frame = +2
Query: 356 DAKNKIQTHLAKTLQEIFQTEMTIESIKKAIKDKTAFLKVAQTRLDERTRRPNIELCRDM 415
D K K++ HL K + +I + E I ++KAI DK A +K+A TRLD RT RPN+ELCRD
Sbjct: 5 DTKGKLEDHLNKIIGQIKEIEENISRLQKAIADKEAPMKLAHTRLDTRTNRPNVELCRDA 184
Query: 416 AQLRLVNEVHEVDDTIQTLQQRLRDAEDTLQSLVHIKATLEYDLAVKANSLYIDQEKCMS 475
Q R + EV E++ ++ LQ RL D +D+L+ L + LE D+ VK+N+L+ID+ +CM
Sbjct: 185 VQYRPIGEVGELECSLAQLQSRLADTQDSLKGLTRNQLDLEDDIQVKSNTLFIDEVECMG 364
Query: 476 MRKS 479
MRKS
Sbjct: 365 MRKS 376
>36475
Length = 841
Score = 67.0 bits (162), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 29/72 (40%), Positives = 53/72 (73%)
Frame = +3
Query: 418 LRLVNEVHEVDDTIQTLQQRLRDAEDTLQSLVHIKATLEYDLAVKANSLYIDQEKCMSMR 477
RLV EV+E+ +I L+ +L A+++L+ L + +LE +++VK NS++ID++KCM++R
Sbjct: 207 FRLVGEVNEICQSIDALKNQLNQAQNSLKDLQDNRMSLEKEISVKKNSIFIDRDKCMTVR 386
Query: 478 KSYPNTLRLVGF 489
YP+T++L G+
Sbjct: 387 TRYPSTVKLQGY 422
>31693
Length = 851
Score = 62.0 bits (149), Expect = 5e-10, Method: Compositional matrix adjust.
Identities = 29/54 (53%), Positives = 40/54 (74%)
Frame = -2
Query: 393 LKVAQTRLDERTRRPNIELCRDMAQLRLVNEVHEVDDTIQTLQQRLRDAEDTLQ 446
+KVAQTRL+ RT RPN+ELCRD Q LV EV+E+ +I L+ +L AE++L+
Sbjct: 604 MKVAQTRLNSRTYRPNVELCRDPVQYALVGEVNEICQSIDALKNQLNQAENSLK 443
Score = 54.3 bits (129), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 43/139 (30%), Positives = 64/139 (46%), Gaps = 13/139 (9%)
Frame = -1
Query: 364 HLAKTLQEIFQTEMTIESIKKAIK----------DKTAFLKVAQTR---LDERTRRPNIE 410
+L K EI Q E I+S+K AI+ D F + R RT P
Sbjct: 692 NLKKVCGEIAQQEKNIDSLKAAIRAKEDPHEGGSDTPQFTNLPAQRGAVQGPRTVCPGG* 513
Query: 411 LCRDMAQLRLVNEVHEVDDTIQTLQQRLRDAEDTLQSLVHIKATLEYDLAVKANSLYIDQ 470
RD+ R E E + QSL + +LE +++VK NS++ID+
Sbjct: 512 GERDLPVYRRPQEPAE-------------PGGELAQSLQDNRMSLEKEISVKKNSIFIDR 372
Query: 471 EKCMSMRKSYPNTLRLVGF 489
+KCM++R YP+T++L GF
Sbjct: 371 DKCMTVRTRYPSTVKLQGF 315
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000330131 | hsapiens_gene_ensembl | Tubulin
alpha-4A chain (Tubulin alpha-1 chain) (Alpha-tubulin 1)
(Testis-specific alpha-tubulin) (Tubulin H2-alpha).
[Source:Uniprot/SWISSPROT;Acc:P68366]
(266 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
12457 361 e-107
00276 323 3e-89
06360 253 6e-68
03702 218 8e-58
16482 186 1e-47
25015 103 7e-23
05902 69 2e-12
39157 65 3e-11
13181 60 1e-09
04882 48 5e-06
26320 27 6.3
32824 27 9.3
>12457
Length = 781
Score = 361 bits (926), Expect(3) = e-107, Method: Compositional matrix adjust.
Identities = 172/196 (87%), Positives = 179/196 (91%)
Frame = -1
Query: 32 FVDLEPTVIDEIRNGPYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDPVLDRIRKLS 91
VDLEPTV+DE+R G YRQLFHPEQL+TGKEDAANNYARGHYTIGKEI+D VLDRIRKL+
Sbjct: 718 LVDLEPTVVDEVRTGTYRQLFHPEQLVTGKEDAANNYARGHYTIGKEIVDLVLDRIRKLA 539
Query: 92 DQCTGLQGFLVFHXXXXXXXXXXXXLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYN 151
DQCTGLQGFL+FH LLMERLSVDYGKKSKLEF+IYPAPQVSTAVVEPYN
Sbjct: 538 DQCTGLQGFLIFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFAIYPAPQVSTAVVEPYN 359
Query: 152 SILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDG 211
SILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLI QIVSSITASLRFDG
Sbjct: 358 SILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDG 179
Query: 212 ALNVDLTEFQTNLVPY 227
ALNVDLTEFQTNLVPY
Sbjct: 178 ALNVDLTEFQTNLVPY 131
Score = 36.6 bits (83), Expect(3) = e-107, Method: Compositional matrix adjust.
Identities = 19/28 (67%), Positives = 19/28 (67%)
Frame = -2
Query: 10 GDDSFTTFFCETGAGKHVPRAVFVDLEP 37
GDDSFT ETGAGKHVPRAV P
Sbjct: 780 GDDSFTPL-SETGAGKHVPRAVSSXXSP 700
Score = 29.3 bits (64), Expect(3) = e-107, Method: Compositional matrix adjust.
Identities = 15/24 (62%), Positives = 17/24 (70%)
Frame = -2
Query: 243 KRHTTSSCRWQRSPMPALSLPTRW 266
+R T SS Q+SPMPALS P RW
Sbjct: 81 RRPTMSS*L*QKSPMPALSQPIRW 10
>00276
Length = 1330
Score = 323 bits (827), Expect(2) = 3e-89, Method: Compositional matrix adjust.
Identities = 158/182 (86%), Positives = 163/182 (89%)
Frame = -3
Query: 46 GPYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDPVLDRIRKLSDQCTGLQGFLVFHX 105
G YRQL PEQL+TGKEDAANNYARGHYTIGKE++D VLDRIRKL+DQCTGLQGFL+FH
Sbjct: 1325 GTYRQL-SPEQLVTGKEDAANNYARGHYTIGKELVDLVLDRIRKLADQCTGLQGFLIFHS 1149
Query: 106 XXXXXXXXXXXLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDC 165
L MERLSVDYGKKSKLEF IYPAPQVSTAVVEPYNSILTTHTTLEHSDC
Sbjct: 1148 FGGGTGSGFTSLXMERLSVDYGKKSKLEFXIYPAPQVSTAVVEPYNSILTTHTTLEHSDC 969
Query: 166 AFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLV 225
AFMVDNEAIYDICRRNLDIERPTYTNLNRLI QIVSSITASLRFDGALNVDLTEFQTNLV
Sbjct: 968 AFMVDNEAIYDICRRNLDIERPTYTNLNRLIXQIVSSITASLRFDGALNVDLTEFQTNLV 789
Query: 226 PY 227
PY
Sbjct: 788 PY 783
Score = 23.1 bits (48), Expect(2) = 3e-89, Method: Compositional matrix adjust.
Identities = 10/15 (66%), Positives = 10/15 (66%)
Frame = -1
Query: 252 WQRSPMPALSLPTRW 266
W RSP PA S PT W
Sbjct: 706 WLRSPTPASSXPTSW 662
>06360
Length = 1896
Score = 253 bits (646), Expect = 6e-68, Method: Compositional matrix adjust.
Identities = 119/143 (83%), Positives = 126/143 (88%)
Frame = -1
Query: 1 MPSDKTIGGGDDSFTTFFCETGAGKHVPRAVFVDLEPTVIDEIRNGPYRQLFHPEQLITG 60
MPSDKTIGGGDDSF TFF ETGAGKHVPRAVFVDLEPTV+DE+R G YRQLFHPEQL+TG
Sbjct: 1605 MPSDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVVDEVRTGTYRQLFHPEQLVTG 1426
Query: 61 KEDAANNYARGHYTIGKEIIDPVLDRIRKLSDQCTGLQGFLVFHXXXXXXXXXXXXLLME 120
KEDAANNYARGHYTIGKEI+D VLDRIRKL+DQCTGLQGFL+FH LLME
Sbjct: 1425 KEDAANNYARGHYTIGKEIVDLVLDRIRKLADQCTGLQGFLIFHSFGGGTGSGFTSLLME 1246
Query: 121 RLSVDYGKKSKLEFSIYPAPQVS 143
RLSVDYGKKSKLEF+IYPAPQVS
Sbjct: 1245 RLSVDYGKKSKLEFAIYPAPQVS 1177
>03702
Length = 1932
Score = 218 bits (554), Expect(2) = 8e-58, Method: Compositional matrix adjust.
Identities = 108/118 (91%), Positives = 110/118 (93%)
Frame = +1
Query: 120 ERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICR 179
ERLSVDYGKKSKLEF+IYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICR
Sbjct: 1459 ERLSVDYGKKSKLEFAIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICR 1638
Query: 180 RNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYASTSPWPPMH 237
RNLDIERP YTNLNRLI QIVSSITASLRFDGALNVDLTEFQTNLVP + P PP H
Sbjct: 1639 RNLDIERPXYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVP--TPHPLPPGH 1806
Score = 23.5 bits (49), Expect(2) = 8e-58, Method: Compositional matrix adjust.
Identities = 13/24 (54%), Positives = 15/24 (62%)
Frame = +2
Query: 243 KRHTTSSCRWQRSPMPALSLPTRW 266
+R T SS + PMPALS PT W
Sbjct: 1829 RRLTMSS*LLLK*PMPALSRPTSW 1900
>16482
Length = 837
Score = 186 bits (471), Expect = 1e-47, Method: Compositional matrix adjust.
Identities = 86/202 (42%), Positives = 127/202 (62%)
Frame = +1
Query: 12 DSFTTFFCETGAGKHVPRAVFVDLEPTVIDEIRNGPYRQLFHPEQLITGKEDAANNYARG 71
+ ++ E GK+VPRAV VDLEP +D +R+GP+ Q+F P+ + G+ A NN+A+G
Sbjct: 232 ERINVYYNEATGGKYVPRAVLVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKG 411
Query: 72 HYTIGKEIIDPVLDRIRKLSDQCTGLQGFLVFHXXXXXXXXXXXXLLMERLSVDYGKKSK 131
HYT G E++D VLD +RK ++ C LQGF + H LL+ ++ +Y +
Sbjct: 412 HYTEGAELVDSVLDVVRKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIM 591
Query: 132 LEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTN 191
FS+ P+P+VS VVEPYN+ L+ H +E++D + +DNEA+YDIC R L + PTY +
Sbjct: 592 NTFSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGD 771
Query: 192 LNRLISQIVSSITASLRFDGAL 213
LN L+S +S +T LRF G L
Sbjct: 772 LNHLVSATMSGVTTCLRFPGQL 837
>25015
Length = 458
Score = 103 bits (257), Expect = 7e-23, Method: Compositional matrix adjust.
Identities = 43/90 (47%), Positives = 62/90 (68%)
Frame = -3
Query: 15 TTFFCETGAGKHVPRAVFVDLEPTVIDEIRNGPYRQLFHPEQLITGKEDAANNYARGHYT 74
++ E GK+VPRAV VDLEP +D +R+GP+ Q+F P+ + G+ A NN+A+GHYT
Sbjct: 279 NVYYNEATGGKYVPRAVLVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYT 100
Query: 75 IGKEIIDPVLDRIRKLSDQCTGLQGFLVFH 104
G E++D VLD +RK ++ C LQGF + H
Sbjct: 99 EGAELVDSVLDVVRKEAESCDCLQGFQLTH 10
>05902
Length = 1127
Score = 69.3 bits (168), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 39/110 (35%), Positives = 69/110 (62%), Gaps = 1/110 (0%)
Frame = +2
Query: 118 LMERLSVDYGKKSKLEFSIYP-APQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYD 176
L+E+L+ + KK +S++P ++S VV+PYNS+LT +++DC ++DN A+
Sbjct: 65 LLEKLNDRFPKKLIQTYSVFPNVDEISDVVVQPYNSLLTLKRLTQNADCVVVLDNTALNR 244
Query: 177 ICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVP 226
I L I+ PT+ +N+L+S ++S+ T +LR+ G +N DL +L+P
Sbjct: 245 IAADRLHIDTPTFAQVNQLVSTVMSTSTTTLRYPGYMNNDLIGLIASLIP 394
>39157
Length = 488
Score = 64.7 bits (156), Expect = 3e-11, Method: Compositional matrix adjust.
Identities = 32/81 (39%), Positives = 50/81 (61%), Gaps = 3/81 (3%)
Frame = -1
Query: 12 DSFTTFFCETGAGKHVPRAVFVDLEPTVIDEIRNG-PYR-QLFHPEQLITGKEDAANNYA 69
+ ++ E GK+VPRAV VDLEP +D +R+G P+ ++F P+ + G+ A NN+
Sbjct: 311 ERINVYYNEATGGKYVPRAVLVDLEPGTMDSVRSGSPFGPKIFRPDNFVFGQSGAGNNWG 132
Query: 70 RGHYTI-GKEIIDPVLDRIRK 89
+ T G E++D VLD +RK
Sbjct: 131 QKDTTQRGAELVDSVLDVVRK 69
>13181
Length = 1092
Score = 59.7 bits (143), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 26/53 (49%), Positives = 34/53 (64%)
Frame = -3
Query: 175 YDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPY 227
YDIC R L + PTY +LN L+S +S +T LRF G LN DL + N+VP+
Sbjct: 1090 YDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPF 932
>04882
Length = 1136
Score = 47.8 bits (112), Expect = 5e-06, Method: Compositional matrix adjust.
Identities = 20/44 (45%), Positives = 28/44 (63%)
Frame = +2
Query: 184 IERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPY 227
+ PTY +LN L+S +S +T LRF G LN DL + N+VP+
Sbjct: 314 VHTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPF 445
>26320
Length = 410
Score = 27.3 bits (59), Expect = 6.3, Method: Compositional matrix adjust.
Identities = 14/35 (40%), Positives = 17/35 (48%), Gaps = 5/35 (14%)
Frame = -3
Query: 237 HQSSLQKRHTTSSCRWQRSPMPAL-----SLPTRW 266
HQ++L H S C + RS PAL LP W
Sbjct: 159 HQNTLHNEH*DSCCGFNRSXAPALLATRDGLPNTW 55
>32824
Length = 558
Score = 26.9 bits (58), Expect = 9.3, Method: Compositional matrix adjust.
Identities = 18/52 (34%), Positives = 23/52 (44%), Gaps = 1/52 (1%)
Frame = -2
Query: 206 SLRFDGALNVDLTEFQTNLVPYASTSPWPPMHQSSLQKRHTTSSCR-WQRSP 256
+L+ T Q NL Y + S PP L+KR +SSCR W P
Sbjct: 536 TLKLTSQNQTHYTALQINLAFYHTLSLRPPYI*LLLRKRAMSSSCRAWNLQP 381
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000345259 | hsapiens_gene_ensembl | Protein 4.1
(Band 4.1) (P4.1) (EPB4.1) (4.1R).
[Source:Uniprot/SWISSPROT;Acc:P11171]
(864 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
00990 387 e-107
18811 187 2e-47
11374 177 1e-44
17332 145 7e-35
13951 55 5e-17
28244 79 9e-15
08363 69 1e-11
03469 65 8e-11
05888 50 6e-06
12829 32 0.96
20292 31 2.5
>00990
Length = 3161
Score = 387 bits (994), Expect = e-107, Method: Compositional matrix adjust.
Identities = 187/363 (51%), Positives = 258/363 (71%), Gaps = 5/363 (1%)
Frame = +3
Query: 183 EVKEESPQSKAETELKASQKPIRKHRNMHCKVSLLDDTVYECVVEKHAKGQDLLKRVCEH 242
EV EES + + K+ QK R + + +V LLD ++++A+G++L +VC+H
Sbjct: 180 EV*EESQ*NGRQDGSKSPQKQ-RTGKGFNYEVVLLDGEHVNFELDRNAEGRELFDKVCQH 356
Query: 243 LNLLEEDYFGLAIWDNATS---KTWLDSAKEIKKQVRGVPWNFTFNVKFYPPDPAQLTED 299
L+L+E+DYFGL D S K WL K I KQ +G PW F F +KFYPPDP QL E
Sbjct: 357 LDLIEKDYFGLQFVDERISNHLKCWLSPDKRISKQKKGGPWLFDFALKFYPPDPTQLRES 536
Query: 300 ITRYYLCLQLRQDIVAGRLPCSFATLALLGSYTIQSELGDYDPELH-GVDYVSDFKLAPN 358
+TR+ + LQ R+DI++G+LP ++ T A+LGSY +Q+++GDYDP H GV+Y+ D APN
Sbjct: 537 LTRWLVVLQTRRDILSGKLPATYLTQAMLGSYCVQADVGDYDPNEHRGVEYIRDTPFAPN 716
Query: 359 QTKELEEKVMELHKSYRSMTPAQADLEFLENAKKLSMYGVDLHKAKDLEGVDIILGVCSS 418
QT +L EK++ELH+ ++ TP +A+ FLENAKKL+MYGVDLH A+D+ VDI+LGVC+S
Sbjct: 717 QTIDLLEKIVELHRQHKGQTPDEAETNFLENAKKLAMYGVDLHAAQDVNNVDIMLGVCAS 896
Query: 419 GLLVYKDKLRINRFPWPKVLKISYKRSSFFIKIRPGEQEQYESTIGFKLPSYRAAKKLWK 478
GL VY++KLRI+RF WPK+LKISYKR F+IK+RP + E++ FKL ++R AK+LWK
Sbjct: 897 GLQVYREKLRISRFVWPKILKISYKRRQFYIKVRPSDNSAMENSFCFKLATHRLAKRLWK 1076
Query: 479 VCVEHHTFFRLTSTD-TIPKSKFLALGSKFRYSGRTQAQTRQASALIDRPAPHFERTASK 537
+CVEHH FFRL + + + F LGSKFRYSGRT QTRQ+S ++DRP P+FER+
Sbjct: 1077ICVEHHAFFRLREAEQSQNAAMFPRLGSKFRYSGRTLYQTRQSSQILDRPNPYFERSQPA 1256
Query: 538 RAS 540
R+S
Sbjct: 1257RSS 1265
Score = 41.6 bits (96), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 21/55 (38%), Positives = 33/55 (60%), Gaps = 2/55 (3%)
Frame = +3
Query: 808 KGGISETRIEKRIVITG--DADIDHDQVLVQAIKEAKEQHPDMSVTKVVVHQETE 860
K GI TR+E ++V++ D + D+D L AI+ E +PDMSV ++ Q+ E
Sbjct: 2145 KDGIQHTRVEHKVVLSSADDEEFDYDAALADAIRSVTEFNPDMSVERIECVQQIE 2309
>18811
Length = 478
Score = 187 bits (475), Expect = 2e-47, Method: Compositional matrix adjust.
Identities = 79/134 (58%), Positives = 108/134 (80%)
Frame = -2
Query: 345 HGVDYVSDFKLAPNQTKELEEKVMELHKSYRSMTPAQADLEFLENAKKLSMYGVDLHKAK 404
HG DY+ D APNQ EL EK++ELH+ ++ TP +A++ +LENAKKLSMYGVDLH A+
Sbjct: 402 HGADYIKDIPFAPNQAPELLEKIVELHRQHKGQTPDEAEVNYLENAKKLSMYGVDLHAAQ 223
Query: 405 DLEGVDIILGVCSSGLLVYKDKLRINRFPWPKVLKISYKRSSFFIKIRPGEQEQYESTIG 464
D+ VDI+LGVCSSGL VY+DKLRI+RF WPK++KISYKR F++K+RP + + E+++
Sbjct: 222 DVNNVDIMLGVCSSGLQVYRDKLRISRFVWPKIIKISYKRKHFYVKVRPADNKGLETSVS 43
Query: 465 FKLPSYRAAKKLWK 478
F+LP++R AK+LWK
Sbjct: 42 FRLPTHRLAKRLWK 1
>11374
Length = 800
Score = 177 bits (449), Expect = 1e-44, Method: Compositional matrix adjust.
Identities = 80/140 (57%), Positives = 104/140 (74%), Gaps = 1/140 (0%)
Frame = +3
Query: 400 LHKAKDLEGVDIILGVCSSGLLVYKDKLRINRFPWPKVLKISYKRSSFFIKIRPGEQEQY 459
LH A+D+ VDI+LGVC+SGL VY++KLRI+RF WPK+LKISYKR F+IK+RP +
Sbjct: 3 LHAAQDVNNVDIMLGVCASGLQVYREKLRISRFVWPKILKISYKRRQFYIKVRPSDNSAM 182
Query: 460 ESTIGFKLPSYRAAKKLWKVCVEHHTFFRLTSTD-TIPKSKFLALGSKFRYSGRTQAQTR 518
E++ FKL ++R AK+LWK+CVEHH FFRL + + + F LGSKFRYSGRT QTR
Sbjct: 183 ENSFCFKLATHRLAKRLWKICVEHHAFFRLREAEQSQNAAMFPRLGSKFRYSGRTLYQTR 362
Query: 519 QASALIDRPAPHFERTASKR 538
+S +DRP P+FER+ R
Sbjct: 363 HSSQTLDRPDPYFERSQPAR 422
>17332
Length = 473
Score = 145 bits (366), Expect = 7e-35, Method: Compositional matrix adjust.
Identities = 74/157 (47%), Positives = 100/157 (63%), Gaps = 2/157 (1%)
Frame = +2
Query: 218 DDTVYECVVEKHAKGQDLLKRVCEHLNLLEEDYFGLAIWDNATSKTWLDSAKEIKKQVRG 277
DD+ ++ V+ + KG L ++VCE LNL E+DYFGL D + WLD K + Q++G
Sbjct: 2 DDSDHQLQVKGNWKGILLQEKVCELLNLHEKDYFGLRFIDASGQTHWLDGNKSLSSQLKG 181
Query: 278 V--PWNFTFNVKFYPPDPAQLTEDITRYYLCLQLRQDIVAGRLPCSFATLALLGSYTIQS 335
P F VKFY DP +L E+ITRY LQ++QDI+ GRLP +F + L +Y +QS
Sbjct: 182 CQTPHKLYFGVKFYAADPCKLREEITRYLFFLQVKQDILQGRLPVTFDEASELCAYAVQS 361
Query: 336 ELGDYDPELHGVDYVSDFKLAPNQTKELEEKVMELHK 372
ELGD+DP H YVS+F PNQT+ELE +V LH+
Sbjct: 362 ELGDFDPRQHTDGYVSEFCFIPNQTEELERRVAGLHR 472
>13951
Length = 720
Score = 55.1 bits (131), Expect(2) = 5e-17, Method: Compositional matrix adjust.
Identities = 35/92 (38%), Positives = 53/92 (57%), Gaps = 4/92 (4%)
Frame = -2
Query: 186 EESPQSKAE-TELKASQKPIRKHRNMHCKVSLLDDTVYECVVEKHAKGQDLLKRVCEHLN 244
E+SP + TE K+ QK R + + +V LLD ++++A+G++L +VC+HL+
Sbjct: 464 EKSPSEMGDKTEDKSPQKQ-RTGKGFNYEVVLLDGEHVNFELDRNAEGRELFDKVCQHLD 288
Query: 245 LLEEDYFGLAIWDNATS---KTWLDSAKEIKK 273
L+E+DYFGL D S K WL K I K
Sbjct: 287 LIEKDYFGLQFVDERISNHLKCWLSPDKRISK 192
Score = 51.6 bits (122), Expect(2) = 5e-17, Method: Composition-based stats.
Identities = 23/50 (46%), Positives = 31/50 (62%)
Frame = -1
Query: 269 KEIKKQVRGVPWNFTFNVKFYPPDPAQLTEDITRYYLCLQLRQDIVAGRL 318
K+ + + +G PW F F +KFYPPDP QL E +TR+ + L VAG L
Sbjct: 204 KDFQNRKKGGPWLFDFALKFYPPDPTQLRESLTRWLVVLH-----VAGEL 70
>28244
Length = 422
Score = 78.6 bits (192), Expect = 9e-15, Method: Composition-based stats.
Identities = 47/124 (37%), Positives = 67/124 (54%), Gaps = 4/124 (3%)
Frame = -1
Query: 421 LVYKDKLRINRFPWPKVLKISYKRSSF-FIKIRPGEQEQYESTIG-FKLPSYRAAKKLWK 478
LV++ +I F WPK+ ++ +K + + E Q + I F+L S +A K LWK
Sbjct: 422 LVFEGNXKIGLFFWPKMTRLDFKGKKLTLVAVEDDENGQSQDHIFVFRLQSEKACKHLWK 243
Query: 479 VCVEHHTFFRLTSTDTIPKSK--FLALGSKFRYSGRTQAQTRQASALIDRPAPHFERTAS 536
VEHH FFRL P ++ F +GS+FRYSGRT+ QT + R + FER S
Sbjct: 242 CAVEHHAFFRLKGPVQGPNARQNFFRMGSRFRYSGRTEYQTSTMNRA--RRSVKFERKPS 69
Query: 537 KRAS 540
+R S
Sbjct: 68 QRYS 57
>08363
Length = 1878
Score = 68.6 bits (166), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 45/126 (35%), Positives = 67/126 (53%), Gaps = 1/126 (0%)
Frame = +1
Query: 729 PPLVKTQTVTISDNANAVKSEIPTKDVPIVHTETKTITYEAAQTDDNSGDLDPGVLLTAX 788
PP V T++V + V +PTK+VP+V TET+T+TYE + D + GVL++A
Sbjct: 115 PPTVATESVHYQPDVEEVP--VPTKNVPLVKTETRTVTYER---EGFPFDGEDGVLVSAS 279
Query: 789 XXXXXXXXXXXXXXXXXXVKGGISETRIEKRIVITG-DADIDHDQVLVQAIKEAKEQHPD 847
K G+ ETR+E R+V++ D D D+D L AI+ E +PD
Sbjct: 280 SHSTRMQTIETTTYKTE--KDGVQETRVEHRVVLSSTDDDFDYDAALADAIRSVTEFNPD 453
Query: 848 MSVTKV 853
MSV ++
Sbjct: 454 MSVERI 471
>03469
Length = 1275
Score = 65.5 bits (158), Expect = 8e-11, Method: Compositional matrix adjust.
Identities = 43/116 (37%), Positives = 63/116 (54%), Gaps = 2/116 (1%)
Frame = -3
Query: 750 IPTKDVPIVHTETKTITYEAAQTDDNSGDLDPGVLLTAXXXXXXXXXXXXXXXXXXXVKG 809
+PTK+VP+V TET+T+TYE + D + GVL++A K
Sbjct: 1258 VPTKNVPLVKTETRTVTYER---EGFPFDGEDGVLVSASSHSTRMQTIETTTYKTE--KD 1094
Query: 810 GISETRIEKRIVITG-DADIDHDQVLVQAIKEAKEQHPDMSVTKV-VVHQETEIAD 863
G+ ETR+E R+V++ D D D+D L AI+ E +PDMSV ++ V Q E+ D
Sbjct: 1093 GVQETRVEHRVVLSSTDDDFDYDAALADAIRSVTEFNPDMSVERIECVQQIEEVKD 926
>05888
Length = 490
Score = 49.7 bits (117), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 22/36 (61%), Positives = 26/36 (72%)
Frame = -2
Query: 503 LGSKFRYSGRTQAQTRQASALIDRPAPHFERTASKR 538
LGSKFRYSGRT Q R +S +DRP P+FER+ R
Sbjct: 489 LGSKFRYSGRTLYQARHSSQTLDRPDPYFERSQPAR 382
>12829
Length = 2357
Score = 32.0 bits (71), Expect = 0.96, Method: Compositional matrix adjust.
Identities = 14/40 (35%), Positives = 24/40 (60%)
Frame = -2
Query: 124 EEIILKAPIAAPEPELKTDPSLDLHSLSSAETQPAQEELR 163
EEI+L +P+A+P+P+ PS+ + + S Q A+ R
Sbjct: 1669 EEIVLVSPLASPQPDFPMSPSVSVLGVPSPRIQTARSPSR 1550
>20292
Length = 1014
Score = 30.8 bits (68), Expect = 2.5, Method: Compositional matrix adjust.
Identities = 18/48 (37%), Positives = 23/48 (47%)
Frame = +3
Query: 214 VSLLDDTVYECVVEKHAKGQDLLKRVCEHLNLLEEDYFGLAIWDNATS 261
SLL D YEC +E H Q +L E ++ L GL + N TS
Sbjct: 567 FSLLQDVSYECCIEVHGPRQTIL----EAMSHLTSKDTGLTLAANGTS 698
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000348397 | hsapiens_gene_ensembl | Protein 4.1
(Band 4.1) (P4.1) (EPB4.1) (4.1R).
[Source:Uniprot/SWISSPROT;Acc:P11171]
(831 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
00990 386 e-107
18811 187 2e-47
11374 177 2e-44
17332 145 7e-35
13951 55 5e-17
28244 79 8e-15
08363 68 1e-11
03469 65 9e-11
05888 49 6e-06
12829 32 0.95
20292 31 2.2
>00990
Length = 3161
Score = 386 bits (992), Expect = e-107, Method: Compositional matrix adjust.
Identities = 187/363 (51%), Positives = 258/363 (71%), Gaps = 5/363 (1%)
Frame = +3
Query: 183 EVKEESPQSKAETELKASQKPIRKHRNMHCKVSLLDDTVYECVVEKHAKGQDLLKRVCEH 242
EV EES + + K+ QK R + + +V LLD ++++A+G++L +VC+H
Sbjct: 180 EV*EESQ*NGRQDGSKSPQKQ-RTGKGFNYEVVLLDGEHVNFELDRNAEGRELFDKVCQH 356
Query: 243 LNLLEEDYFGLAIWDNATS---KTWLDSAKEIKKQVRGVPWNFTFNVKFYPPDPAQLTED 299
L+L+E+DYFGL D S K WL K I KQ +G PW F F +KFYPPDP QL E
Sbjct: 357 LDLIEKDYFGLQFVDERISNHLKCWLSPDKRISKQKKGGPWLFDFALKFYPPDPTQLRES 536
Query: 300 ITRYYLCLQLRQDIVAGRLPCSFATLALLGSYTIQSELGDYDPELH-GVDYVSDFKLAPN 358
+TR+ + LQ R+DI++G+LP ++ T A+LGSY +Q+++GDYDP H GV+Y+ D APN
Sbjct: 537 LTRWLVVLQTRRDILSGKLPATYLTQAMLGSYCVQADVGDYDPNEHRGVEYIRDTPFAPN 716
Query: 359 QTKELEEKVMELHKSYRSMTPAQADLEFLENAKKLSMYGVDLHKAKDLEGVDIILGVCSS 418
QT +L EK++ELH+ ++ TP +A+ FLENAKKL+MYGVDLH A+D+ VDI+LGVC+S
Sbjct: 717 QTIDLLEKIVELHRQHKGQTPDEAETNFLENAKKLAMYGVDLHAAQDVNNVDIMLGVCAS 896
Query: 419 GLLVYKDKLRINRFPWPKVLKISYKRSSFFIKIRPGEQEQYESTIGFKLPSYRAAKKLWK 478
GL VY++KLRI+RF WPK+LKISYKR F+IK+RP + E++ FKL ++R AK+LWK
Sbjct: 897 GLQVYREKLRISRFVWPKILKISYKRRQFYIKVRPSDNSAMENSFCFKLATHRLAKRLWK 1076
Query: 479 VCVEHHTFFRLTSTD-TIPKSKFLALGSKFRYSGRTQAQTRQASALIDRPAPHFERTASK 537
+CVEHH FFRL + + + F LGSKFRYSGRT QTRQ+S ++DRP P+FER+
Sbjct: 1077ICVEHHAFFRLREAEQSQNAAMFPRLGSKFRYSGRTLYQTRQSSQILDRPNPYFERSQPA 1256
Query: 538 RAS 540
R+S
Sbjct: 1257RSS 1265
Score = 41.6 bits (96), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 21/55 (38%), Positives = 33/55 (60%), Gaps = 2/55 (3%)
Frame = +3
Query: 775 KGGISETRIEKRIVITG--DADIDHDQVLVQAIKEAKEQHPDMSVTKVVVHQETE 827
K GI TR+E ++V++ D + D+D L AI+ E +PDMSV ++ Q+ E
Sbjct: 2145 KDGIQHTRVEHKVVLSSADDEEFDYDAALADAIRSVTEFNPDMSVERIECVQQIE 2309
>18811
Length = 478
Score = 187 bits (474), Expect = 2e-47, Method: Compositional matrix adjust.
Identities = 79/134 (58%), Positives = 108/134 (80%)
Frame = -2
Query: 345 HGVDYVSDFKLAPNQTKELEEKVMELHKSYRSMTPAQADLEFLENAKKLSMYGVDLHKAK 404
HG DY+ D APNQ EL EK++ELH+ ++ TP +A++ +LENAKKLSMYGVDLH A+
Sbjct: 402 HGADYIKDIPFAPNQAPELLEKIVELHRQHKGQTPDEAEVNYLENAKKLSMYGVDLHAAQ 223
Query: 405 DLEGVDIILGVCSSGLLVYKDKLRINRFPWPKVLKISYKRSSFFIKIRPGEQEQYESTIG 464
D+ VDI+LGVCSSGL VY+DKLRI+RF WPK++KISYKR F++K+RP + + E+++
Sbjct: 222 DVNNVDIMLGVCSSGLQVYRDKLRISRFVWPKIIKISYKRKHFYVKVRPADNKGLETSVS 43
Query: 465 FKLPSYRAAKKLWK 478
F+LP++R AK+LWK
Sbjct: 42 FRLPTHRLAKRLWK 1
>11374
Length = 800
Score = 177 bits (449), Expect = 2e-44, Method: Compositional matrix adjust.
Identities = 80/140 (57%), Positives = 104/140 (74%), Gaps = 1/140 (0%)
Frame = +3
Query: 400 LHKAKDLEGVDIILGVCSSGLLVYKDKLRINRFPWPKVLKISYKRSSFFIKIRPGEQEQY 459
LH A+D+ VDI+LGVC+SGL VY++KLRI+RF WPK+LKISYKR F+IK+RP +
Sbjct: 3 LHAAQDVNNVDIMLGVCASGLQVYREKLRISRFVWPKILKISYKRRQFYIKVRPSDNSAM 182
Query: 460 ESTIGFKLPSYRAAKKLWKVCVEHHTFFRLTSTD-TIPKSKFLALGSKFRYSGRTQAQTR 518
E++ FKL ++R AK+LWK+CVEHH FFRL + + + F LGSKFRYSGRT QTR
Sbjct: 183 ENSFCFKLATHRLAKRLWKICVEHHAFFRLREAEQSQNAAMFPRLGSKFRYSGRTLYQTR 362
Query: 519 QASALIDRPAPHFERTASKR 538
+S +DRP P+FER+ R
Sbjct: 363 HSSQTLDRPDPYFERSQPAR 422
>17332
Length = 473
Score = 145 bits (366), Expect = 7e-35, Method: Compositional matrix adjust.
Identities = 74/157 (47%), Positives = 100/157 (63%), Gaps = 2/157 (1%)
Frame = +2
Query: 218 DDTVYECVVEKHAKGQDLLKRVCEHLNLLEEDYFGLAIWDNATSKTWLDSAKEIKKQVRG 277
DD+ ++ V+ + KG L ++VCE LNL E+DYFGL D + WLD K + Q++G
Sbjct: 2 DDSDHQLQVKGNWKGILLQEKVCELLNLHEKDYFGLRFIDASGQTHWLDGNKSLSSQLKG 181
Query: 278 V--PWNFTFNVKFYPPDPAQLTEDITRYYLCLQLRQDIVAGRLPCSFATLALLGSYTIQS 335
P F VKFY DP +L E+ITRY LQ++QDI+ GRLP +F + L +Y +QS
Sbjct: 182 CQTPHKLYFGVKFYAADPCKLREEITRYLFFLQVKQDILQGRLPVTFDEASELCAYAVQS 361
Query: 336 ELGDYDPELHGVDYVSDFKLAPNQTKELEEKVMELHK 372
ELGD+DP H YVS+F PNQT+ELE +V LH+
Sbjct: 362 ELGDFDPRQHTDGYVSEFCFIPNQTEELERRVAGLHR 472
>13951
Length = 720
Score = 55.1 bits (131), Expect(2) = 5e-17, Method: Compositional matrix adjust.
Identities = 35/92 (38%), Positives = 53/92 (57%), Gaps = 4/92 (4%)
Frame = -2
Query: 186 EESPQSKAE-TELKASQKPIRKHRNMHCKVSLLDDTVYECVVEKHAKGQDLLKRVCEHLN 244
E+SP + TE K+ QK R + + +V LLD ++++A+G++L +VC+HL+
Sbjct: 464 EKSPSEMGDKTEDKSPQKQ-RTGKGFNYEVVLLDGEHVNFELDRNAEGRELFDKVCQHLD 288
Query: 245 LLEEDYFGLAIWDNATS---KTWLDSAKEIKK 273
L+E+DYFGL D S K WL K I K
Sbjct: 287 LIEKDYFGLQFVDERISNHLKCWLSPDKRISK 192
Score = 51.6 bits (122), Expect(2) = 5e-17, Method: Composition-based stats.
Identities = 23/50 (46%), Positives = 31/50 (62%)
Frame = -1
Query: 269 KEIKKQVRGVPWNFTFNVKFYPPDPAQLTEDITRYYLCLQLRQDIVAGRL 318
K+ + + +G PW F F +KFYPPDP QL E +TR+ + L VAG L
Sbjct: 204 KDFQNRKKGGPWLFDFALKFYPPDPTQLRESLTRWLVVLH-----VAGEL 70
>28244
Length = 422
Score = 79.0 bits (193), Expect = 8e-15, Method: Composition-based stats.
Identities = 47/124 (37%), Positives = 67/124 (54%), Gaps = 4/124 (3%)
Frame = -1
Query: 421 LVYKDKLRINRFPWPKVLKISYKRSSF-FIKIRPGEQEQYESTIG-FKLPSYRAAKKLWK 478
LV++ +I F WPK+ ++ +K + + E Q + I F+L S +A K LWK
Sbjct: 422 LVFEGNXKIGLFFWPKMTRLDFKGKKLTLVAVEDDENGQSQDHIFVFRLQSEKACKHLWK 243
Query: 479 VCVEHHTFFRLTSTDTIPKSK--FLALGSKFRYSGRTQAQTRQASALIDRPAPHFERTAS 536
VEHH FFRL P ++ F +GS+FRYSGRT+ QT + R + FER S
Sbjct: 242 CAVEHHAFFRLKGPVQGPNARQNFFRMGSRFRYSGRTEYQTSTMNRA--RRSVKFERKPS 69
Query: 537 KRAS 540
+R S
Sbjct: 68 QRYS 57
>08363
Length = 1878
Score = 68.2 bits (165), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 45/126 (35%), Positives = 67/126 (53%), Gaps = 1/126 (0%)
Frame = +1
Query: 696 PPLVKTQTVTISDNANAVKSEIPTKDVPIVHTETKTITYEAAQTDDNSGDLDPGVLLTAX 755
PP V T++V + V +PTK+VP+V TET+T+TYE + D + GVL++A
Sbjct: 115 PPTVATESVHYQPDVEEVP--VPTKNVPLVKTETRTVTYER---EGFPFDGEDGVLVSAS 279
Query: 756 XXXXXXXXXXXXXXXXXXVKGGISETRIEKRIVITG-DADIDHDQVLVQAIKEAKEQHPD 814
K G+ ETR+E R+V++ D D D+D L AI+ E +PD
Sbjct: 280 SHSTRMQTIETTTYKTE--KDGVQETRVEHRVVLSSTDDDFDYDAALADAIRSVTEFNPD 453
Query: 815 MSVTKV 820
MSV ++
Sbjct: 454 MSVERI 471
>03469
Length = 1275
Score = 65.5 bits (158), Expect = 9e-11, Method: Compositional matrix adjust.
Identities = 43/116 (37%), Positives = 63/116 (54%), Gaps = 2/116 (1%)
Frame = -3
Query: 717 IPTKDVPIVHTETKTITYEAAQTDDNSGDLDPGVLLTAXXXXXXXXXXXXXXXXXXXVKG 776
+PTK+VP+V TET+T+TYE + D + GVL++A K
Sbjct: 1258 VPTKNVPLVKTETRTVTYER---EGFPFDGEDGVLVSASSHSTRMQTIETTTYKTE--KD 1094
Query: 777 GISETRIEKRIVITG-DADIDHDQVLVQAIKEAKEQHPDMSVTKV-VVHQETEIAD 830
G+ ETR+E R+V++ D D D+D L AI+ E +PDMSV ++ V Q E+ D
Sbjct: 1093 GVQETRVEHRVVLSSTDDDFDYDAALADAIRSVTEFNPDMSVERIECVQQIEEVKD 926
>05888
Length = 490
Score = 49.3 bits (116), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 22/36 (61%), Positives = 26/36 (72%)
Frame = -2
Query: 503 LGSKFRYSGRTQAQTRQASALIDRPAPHFERTASKR 538
LGSKFRYSGRT Q R +S +DRP P+FER+ R
Sbjct: 489 LGSKFRYSGRTLYQARHSSQTLDRPDPYFERSQPAR 382
>12829
Length = 2357
Score = 32.0 bits (71), Expect = 0.95, Method: Compositional matrix adjust.
Identities = 14/40 (35%), Positives = 24/40 (60%)
Frame = -2
Query: 124 EEIILKAPIAAPEPELKTDPSLDLHSLSSAETQPAQEELR 163
EEI+L +P+A+P+P+ PS+ + + S Q A+ R
Sbjct: 1669 EEIVLVSPLASPQPDFPMSPSVSVLGVPSPRIQTARSPSR 1550
>20292
Length = 1014
Score = 30.8 bits (68), Expect = 2.2, Method: Compositional matrix adjust.
Identities = 18/48 (37%), Positives = 23/48 (47%)
Frame = +3
Query: 214 VSLLDDTVYECVVEKHAKGQDLLKRVCEHLNLLEEDYFGLAIWDNATS 261
SLL D YEC +E H Q +L E ++ L GL + N TS
Sbjct: 567 FSLLQDVSYECCIEVHGPRQTIL----EAMSHLTSKDTGLTLAANGTS 698
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000362903 | hsapiens_gene_ensembl | Protein 4.1
(Band 4.1) (P4.1) (EPB4.1) (4.1R).
[Source:Uniprot/SWISSPROT;Acc:P11171]
(720 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
00990 386 e-107
18811 187 2e-47
11374 176 2e-44
17332 145 6e-35
13951 55 5e-16
28244 77 2e-14
05888 49 7e-06
12829 32 0.73
20292 31 1.7
17496 30 2.5
>00990
Length = 3161
Score = 386 bits (991), Expect = e-107, Method: Compositional matrix adjust.
Identities = 187/363 (51%), Positives = 258/363 (71%), Gaps = 5/363 (1%)
Frame = +3
Query: 183 EVKEESPQSKAETELKASQKPIRKHRNMHCKVSLLDDTVYECVVEKHAKGQDLLKRVCEH 242
EV EES + + K+ QK R + + +V LLD ++++A+G++L +VC+H
Sbjct: 180 EV*EESQ*NGRQDGSKSPQKQ-RTGKGFNYEVVLLDGEHVNFELDRNAEGRELFDKVCQH 356
Query: 243 LNLLEEDYFGLAIWDNATS---KTWLDSAKEIKKQVRGVPWNFTFNVKFYPPDPAQLTED 299
L+L+E+DYFGL D S K WL K I KQ +G PW F F +KFYPPDP QL E
Sbjct: 357 LDLIEKDYFGLQFVDERISNHLKCWLSPDKRISKQKKGGPWLFDFALKFYPPDPTQLRES 536
Query: 300 ITRYYLCLQLRQDIVAGRLPCSFATLALLGSYTIQSELGDYDPELH-GVDYVSDFKLAPN 358
+TR+ + LQ R+DI++G+LP ++ T A+LGSY +Q+++GDYDP H GV+Y+ D APN
Sbjct: 537 LTRWLVVLQTRRDILSGKLPATYLTQAMLGSYCVQADVGDYDPNEHRGVEYIRDTPFAPN 716
Query: 359 QTKELEEKVMELHKSYRSMTPAQADLEFLENAKKLSMYGVDLHKAKDLEGVDIILGVCSS 418
QT +L EK++ELH+ ++ TP +A+ FLENAKKL+MYGVDLH A+D+ VDI+LGVC+S
Sbjct: 717 QTIDLLEKIVELHRQHKGQTPDEAETNFLENAKKLAMYGVDLHAAQDVNNVDIMLGVCAS 896
Query: 419 GLLVYKDKLRINRFPWPKVLKISYKRSSFFIKIRPGEQEQYESTIGFKLPSYRAAKKLWK 478
GL VY++KLRI+RF WPK+LKISYKR F+IK+RP + E++ FKL ++R AK+LWK
Sbjct: 897 GLQVYREKLRISRFVWPKILKISYKRRQFYIKVRPSDNSAMENSFCFKLATHRLAKRLWK 1076
Query: 479 VCVEHHTFFRLTSTD-TIPKSKFLALGSKFRYSGRTQAQTRQASALIDRPAPHFERTASK 537
+CVEHH FFRL + + + F LGSKFRYSGRT QTRQ+S ++DRP P+FER+
Sbjct: 1077ICVEHHAFFRLREAEQSQNAAMFPRLGSKFRYSGRTLYQTRQSSQILDRPNPYFERSQPA 1256
Query: 538 RAS 540
R+S
Sbjct: 1257RSS 1265
>18811
Length = 478
Score = 187 bits (474), Expect = 2e-47, Method: Compositional matrix adjust.
Identities = 79/134 (58%), Positives = 108/134 (80%)
Frame = -2
Query: 345 HGVDYVSDFKLAPNQTKELEEKVMELHKSYRSMTPAQADLEFLENAKKLSMYGVDLHKAK 404
HG DY+ D APNQ EL EK++ELH+ ++ TP +A++ +LENAKKLSMYGVDLH A+
Sbjct: 402 HGADYIKDIPFAPNQAPELLEKIVELHRQHKGQTPDEAEVNYLENAKKLSMYGVDLHAAQ 223
Query: 405 DLEGVDIILGVCSSGLLVYKDKLRINRFPWPKVLKISYKRSSFFIKIRPGEQEQYESTIG 464
D+ VDI+LGVCSSGL VY+DKLRI+RF WPK++KISYKR F++K+RP + + E+++
Sbjct: 222 DVNNVDIMLGVCSSGLQVYRDKLRISRFVWPKIIKISYKRKHFYVKVRPADNKGLETSVS 43
Query: 465 FKLPSYRAAKKLWK 478
F+LP++R AK+LWK
Sbjct: 42 FRLPTHRLAKRLWK 1
>11374
Length = 800
Score = 176 bits (447), Expect = 2e-44, Method: Compositional matrix adjust.
Identities = 80/140 (57%), Positives = 104/140 (74%), Gaps = 1/140 (0%)
Frame = +3
Query: 400 LHKAKDLEGVDIILGVCSSGLLVYKDKLRINRFPWPKVLKISYKRSSFFIKIRPGEQEQY 459
LH A+D+ VDI+LGVC+SGL VY++KLRI+RF WPK+LKISYKR F+IK+RP +
Sbjct: 3 LHAAQDVNNVDIMLGVCASGLQVYREKLRISRFVWPKILKISYKRRQFYIKVRPSDNSAM 182
Query: 460 ESTIGFKLPSYRAAKKLWKVCVEHHTFFRLTSTD-TIPKSKFLALGSKFRYSGRTQAQTR 518
E++ FKL ++R AK+LWK+CVEHH FFRL + + + F LGSKFRYSGRT QTR
Sbjct: 183 ENSFCFKLATHRLAKRLWKICVEHHAFFRLREAEQSQNAAMFPRLGSKFRYSGRTLYQTR 362
Query: 519 QASALIDRPAPHFERTASKR 538
+S +DRP P+FER+ R
Sbjct: 363 HSSQTLDRPDPYFERSQPAR 422
>17332
Length = 473
Score = 145 bits (366), Expect = 6e-35, Method: Compositional matrix adjust.
Identities = 74/157 (47%), Positives = 100/157 (63%), Gaps = 2/157 (1%)
Frame = +2
Query: 218 DDTVYECVVEKHAKGQDLLKRVCEHLNLLEEDYFGLAIWDNATSKTWLDSAKEIKKQVRG 277
DD+ ++ V+ + KG L ++VCE LNL E+DYFGL D + WLD K + Q++G
Sbjct: 2 DDSDHQLQVKGNWKGILLQEKVCELLNLHEKDYFGLRFIDASGQTHWLDGNKSLSSQLKG 181
Query: 278 V--PWNFTFNVKFYPPDPAQLTEDITRYYLCLQLRQDIVAGRLPCSFATLALLGSYTIQS 335
P F VKFY DP +L E+ITRY LQ++QDI+ GRLP +F + L +Y +QS
Sbjct: 182 CQTPHKLYFGVKFYAADPCKLREEITRYLFFLQVKQDILQGRLPVTFDEASELCAYAVQS 361
Query: 336 ELGDYDPELHGVDYVSDFKLAPNQTKELEEKVMELHK 372
ELGD+DP H YVS+F PNQT+ELE +V LH+
Sbjct: 362 ELGDFDPRQHTDGYVSEFCFIPNQTEELERRVAGLHR 472
>13951
Length = 720
Score = 55.1 bits (131), Expect(2) = 5e-16, Method: Compositional matrix adjust.
Identities = 35/92 (38%), Positives = 53/92 (57%), Gaps = 4/92 (4%)
Frame = -2
Query: 186 EESPQSKAE-TELKASQKPIRKHRNMHCKVSLLDDTVYECVVEKHAKGQDLLKRVCEHLN 244
E+SP + TE K+ QK R + + +V LLD ++++A+G++L +VC+HL+
Sbjct: 464 EKSPSEMGDKTEDKSPQKQ-RTGKGFNYEVVLLDGEHVNFELDRNAEGRELFDKVCQHLD 288
Query: 245 LLEEDYFGLAIWDNATS---KTWLDSAKEIKK 273
L+E+DYFGL D S K WL K I K
Sbjct: 287 LIEKDYFGLQFVDERISNHLKCWLSPDKRISK 192
Score = 48.1 bits (113), Expect(2) = 5e-16, Method: Compositional matrix adjust.
Identities = 23/50 (46%), Positives = 31/50 (62%)
Frame = -1
Query: 269 KEIKKQVRGVPWNFTFNVKFYPPDPAQLTEDITRYYLCLQLRQDIVAGRL 318
K+ + + +G PW F F +KFYPPDP QL E +TR+ + L VAG L
Sbjct: 204 KDFQNRKKGGPWLFDFALKFYPPDPTQLRESLTRWLVVLH-----VAGEL 70
>28244
Length = 422
Score = 77.4 bits (189), Expect = 2e-14, Method: Composition-based stats.
Identities = 47/124 (37%), Positives = 67/124 (54%), Gaps = 4/124 (3%)
Frame = -1
Query: 421 LVYKDKLRINRFPWPKVLKISYKRSSF-FIKIRPGEQEQYESTIG-FKLPSYRAAKKLWK 478
LV++ +I F WPK+ ++ +K + + E Q + I F+L S +A K LWK
Sbjct: 422 LVFEGNXKIGLFFWPKMTRLDFKGKKLTLVAVEDDENGQSQDHIFVFRLQSEKACKHLWK 243
Query: 479 VCVEHHTFFRLTSTDTIPKSK--FLALGSKFRYSGRTQAQTRQASALIDRPAPHFERTAS 536
VEHH FFRL P ++ F +GS+FRYSGRT+ QT + R + FER S
Sbjct: 242 CAVEHHAFFRLKGPVQGPNARQNFFRMGSRFRYSGRTEYQTSTMNRA--RRSVKFERKPS 69
Query: 537 KRAS 540
+R S
Sbjct: 68 QRYS 57
>05888
Length = 490
Score = 48.9 bits (115), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 22/36 (61%), Positives = 26/36 (72%)
Frame = -2
Query: 503 LGSKFRYSGRTQAQTRQASALIDRPAPHFERTASKR 538
LGSKFRYSGRT Q R +S +DRP P+FER+ R
Sbjct: 489 LGSKFRYSGRTLYQARHSSQTLDRPDPYFERSQPAR 382
>12829
Length = 2357
Score = 32.3 bits (72), Expect = 0.73, Method: Compositional matrix adjust.
Identities = 14/40 (35%), Positives = 24/40 (60%)
Frame = -2
Query: 124 EEIILKAPIAAPEPELKTDPSLDLHSLSSAETQPAQEELR 163
EEI+L +P+A+P+P+ PS+ + + S Q A+ R
Sbjct: 1669 EEIVLVSPLASPQPDFPMSPSVSVLGVPSPRIQTARSPSR 1550
>20292
Length = 1014
Score = 31.2 bits (69), Expect = 1.7, Method: Compositional matrix adjust.
Identities = 18/47 (38%), Positives = 23/47 (48%)
Frame = +3
Query: 215 SLLDDTVYECVVEKHAKGQDLLKRVCEHLNLLEEDYFGLAIWDNATS 261
SLL D YEC +E H Q +L E ++ L GL + N TS
Sbjct: 570 SLLQDVSYECCIEVHGPRQTIL----EAMSHLTSKDTGLTLAANGTS 698
>17496
Length = 461
Score = 30.4 bits (67), Expect = 2.5, Method: Compositional matrix adjust.
Identities = 15/38 (39%), Positives = 23/38 (60%), Gaps = 2/38 (5%)
Frame = +3
Query: 399 DLHKAKDLEGVDIILGVCSSGLL--VYKDKLRINRFPW 434
DLH+A+ +GV ++L SGL +K K +R+PW
Sbjct: 111 DLHRARTFQGVTLLLWETLSGLQKPGWKGKELKSRWPW 224
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000362904 | hsapiens_gene_ensembl | Protein 4.1
(Band 4.1) (P4.1) (EPB4.1) (4.1R).
[Source:Uniprot/SWISSPROT;Acc:P11171]
(864 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
00990 387 e-107
18811 187 2e-47
11374 177 1e-44
17332 145 7e-35
13951 55 5e-17
28244 79 9e-15
08363 69 1e-11
03469 65 8e-11
05888 50 6e-06
12829 32 0.96
20292 31 2.5
>00990
Length = 3161
Score = 387 bits (994), Expect = e-107, Method: Compositional matrix adjust.
Identities = 187/363 (51%), Positives = 258/363 (71%), Gaps = 5/363 (1%)
Frame = +3
Query: 183 EVKEESPQSKAETELKASQKPIRKHRNMHCKVSLLDDTVYECVVEKHAKGQDLLKRVCEH 242
EV EES + + K+ QK R + + +V LLD ++++A+G++L +VC+H
Sbjct: 180 EV*EESQ*NGRQDGSKSPQKQ-RTGKGFNYEVVLLDGEHVNFELDRNAEGRELFDKVCQH 356
Query: 243 LNLLEEDYFGLAIWDNATS---KTWLDSAKEIKKQVRGVPWNFTFNVKFYPPDPAQLTED 299
L+L+E+DYFGL D S K WL K I KQ +G PW F F +KFYPPDP QL E
Sbjct: 357 LDLIEKDYFGLQFVDERISNHLKCWLSPDKRISKQKKGGPWLFDFALKFYPPDPTQLRES 536
Query: 300 ITRYYLCLQLRQDIVAGRLPCSFATLALLGSYTIQSELGDYDPELH-GVDYVSDFKLAPN 358
+TR+ + LQ R+DI++G+LP ++ T A+LGSY +Q+++GDYDP H GV+Y+ D APN
Sbjct: 537 LTRWLVVLQTRRDILSGKLPATYLTQAMLGSYCVQADVGDYDPNEHRGVEYIRDTPFAPN 716
Query: 359 QTKELEEKVMELHKSYRSMTPAQADLEFLENAKKLSMYGVDLHKAKDLEGVDIILGVCSS 418
QT +L EK++ELH+ ++ TP +A+ FLENAKKL+MYGVDLH A+D+ VDI+LGVC+S
Sbjct: 717 QTIDLLEKIVELHRQHKGQTPDEAETNFLENAKKLAMYGVDLHAAQDVNNVDIMLGVCAS 896
Query: 419 GLLVYKDKLRINRFPWPKVLKISYKRSSFFIKIRPGEQEQYESTIGFKLPSYRAAKKLWK 478
GL VY++KLRI+RF WPK+LKISYKR F+IK+RP + E++ FKL ++R AK+LWK
Sbjct: 897 GLQVYREKLRISRFVWPKILKISYKRRQFYIKVRPSDNSAMENSFCFKLATHRLAKRLWK 1076
Query: 479 VCVEHHTFFRLTSTD-TIPKSKFLALGSKFRYSGRTQAQTRQASALIDRPAPHFERTASK 537
+CVEHH FFRL + + + F LGSKFRYSGRT QTRQ+S ++DRP P+FER+
Sbjct: 1077ICVEHHAFFRLREAEQSQNAAMFPRLGSKFRYSGRTLYQTRQSSQILDRPNPYFERSQPA 1256
Query: 538 RAS 540
R+S
Sbjct: 1257RSS 1265
Score = 41.6 bits (96), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 21/55 (38%), Positives = 33/55 (60%), Gaps = 2/55 (3%)
Frame = +3
Query: 808 KGGISETRIEKRIVITG--DADIDHDQVLVQAIKEAKEQHPDMSVTKVVVHQETE 860
K GI TR+E ++V++ D + D+D L AI+ E +PDMSV ++ Q+ E
Sbjct: 2145 KDGIQHTRVEHKVVLSSADDEEFDYDAALADAIRSVTEFNPDMSVERIECVQQIE 2309
>18811
Length = 478
Score = 187 bits (475), Expect = 2e-47, Method: Compositional matrix adjust.
Identities = 79/134 (58%), Positives = 108/134 (80%)
Frame = -2
Query: 345 HGVDYVSDFKLAPNQTKELEEKVMELHKSYRSMTPAQADLEFLENAKKLSMYGVDLHKAK 404
HG DY+ D APNQ EL EK++ELH+ ++ TP +A++ +LENAKKLSMYGVDLH A+
Sbjct: 402 HGADYIKDIPFAPNQAPELLEKIVELHRQHKGQTPDEAEVNYLENAKKLSMYGVDLHAAQ 223
Query: 405 DLEGVDIILGVCSSGLLVYKDKLRINRFPWPKVLKISYKRSSFFIKIRPGEQEQYESTIG 464
D+ VDI+LGVCSSGL VY+DKLRI+RF WPK++KISYKR F++K+RP + + E+++
Sbjct: 222 DVNNVDIMLGVCSSGLQVYRDKLRISRFVWPKIIKISYKRKHFYVKVRPADNKGLETSVS 43
Query: 465 FKLPSYRAAKKLWK 478
F+LP++R AK+LWK
Sbjct: 42 FRLPTHRLAKRLWK 1
>11374
Length = 800
Score = 177 bits (449), Expect = 1e-44, Method: Compositional matrix adjust.
Identities = 80/140 (57%), Positives = 104/140 (74%), Gaps = 1/140 (0%)
Frame = +3
Query: 400 LHKAKDLEGVDIILGVCSSGLLVYKDKLRINRFPWPKVLKISYKRSSFFIKIRPGEQEQY 459
LH A+D+ VDI+LGVC+SGL VY++KLRI+RF WPK+LKISYKR F+IK+RP +
Sbjct: 3 LHAAQDVNNVDIMLGVCASGLQVYREKLRISRFVWPKILKISYKRRQFYIKVRPSDNSAM 182
Query: 460 ESTIGFKLPSYRAAKKLWKVCVEHHTFFRLTSTD-TIPKSKFLALGSKFRYSGRTQAQTR 518
E++ FKL ++R AK+LWK+CVEHH FFRL + + + F LGSKFRYSGRT QTR
Sbjct: 183 ENSFCFKLATHRLAKRLWKICVEHHAFFRLREAEQSQNAAMFPRLGSKFRYSGRTLYQTR 362
Query: 519 QASALIDRPAPHFERTASKR 538
+S +DRP P+FER+ R
Sbjct: 363 HSSQTLDRPDPYFERSQPAR 422
>17332
Length = 473
Score = 145 bits (366), Expect = 7e-35, Method: Compositional matrix adjust.
Identities = 74/157 (47%), Positives = 100/157 (63%), Gaps = 2/157 (1%)
Frame = +2
Query: 218 DDTVYECVVEKHAKGQDLLKRVCEHLNLLEEDYFGLAIWDNATSKTWLDSAKEIKKQVRG 277
DD+ ++ V+ + KG L ++VCE LNL E+DYFGL D + WLD K + Q++G
Sbjct: 2 DDSDHQLQVKGNWKGILLQEKVCELLNLHEKDYFGLRFIDASGQTHWLDGNKSLSSQLKG 181
Query: 278 V--PWNFTFNVKFYPPDPAQLTEDITRYYLCLQLRQDIVAGRLPCSFATLALLGSYTIQS 335
P F VKFY DP +L E+ITRY LQ++QDI+ GRLP +F + L +Y +QS
Sbjct: 182 CQTPHKLYFGVKFYAADPCKLREEITRYLFFLQVKQDILQGRLPVTFDEASELCAYAVQS 361
Query: 336 ELGDYDPELHGVDYVSDFKLAPNQTKELEEKVMELHK 372
ELGD+DP H YVS+F PNQT+ELE +V LH+
Sbjct: 362 ELGDFDPRQHTDGYVSEFCFIPNQTEELERRVAGLHR 472
>13951
Length = 720
Score = 55.1 bits (131), Expect(2) = 5e-17, Method: Compositional matrix adjust.
Identities = 35/92 (38%), Positives = 53/92 (57%), Gaps = 4/92 (4%)
Frame = -2
Query: 186 EESPQSKAE-TELKASQKPIRKHRNMHCKVSLLDDTVYECVVEKHAKGQDLLKRVCEHLN 244
E+SP + TE K+ QK R + + +V LLD ++++A+G++L +VC+HL+
Sbjct: 464 EKSPSEMGDKTEDKSPQKQ-RTGKGFNYEVVLLDGEHVNFELDRNAEGRELFDKVCQHLD 288
Query: 245 LLEEDYFGLAIWDNATS---KTWLDSAKEIKK 273
L+E+DYFGL D S K WL K I K
Sbjct: 287 LIEKDYFGLQFVDERISNHLKCWLSPDKRISK 192
Score = 51.6 bits (122), Expect(2) = 5e-17, Method: Composition-based stats.
Identities = 23/50 (46%), Positives = 31/50 (62%)
Frame = -1
Query: 269 KEIKKQVRGVPWNFTFNVKFYPPDPAQLTEDITRYYLCLQLRQDIVAGRL 318
K+ + + +G PW F F +KFYPPDP QL E +TR+ + L VAG L
Sbjct: 204 KDFQNRKKGGPWLFDFALKFYPPDPTQLRESLTRWLVVLH-----VAGEL 70
>28244
Length = 422
Score = 78.6 bits (192), Expect = 9e-15, Method: Composition-based stats.
Identities = 47/124 (37%), Positives = 67/124 (54%), Gaps = 4/124 (3%)
Frame = -1
Query: 421 LVYKDKLRINRFPWPKVLKISYKRSSF-FIKIRPGEQEQYESTIG-FKLPSYRAAKKLWK 478
LV++ +I F WPK+ ++ +K + + E Q + I F+L S +A K LWK
Sbjct: 422 LVFEGNXKIGLFFWPKMTRLDFKGKKLTLVAVEDDENGQSQDHIFVFRLQSEKACKHLWK 243
Query: 479 VCVEHHTFFRLTSTDTIPKSK--FLALGSKFRYSGRTQAQTRQASALIDRPAPHFERTAS 536
VEHH FFRL P ++ F +GS+FRYSGRT+ QT + R + FER S
Sbjct: 242 CAVEHHAFFRLKGPVQGPNARQNFFRMGSRFRYSGRTEYQTSTMNRA--RRSVKFERKPS 69
Query: 537 KRAS 540
+R S
Sbjct: 68 QRYS 57
>08363
Length = 1878
Score = 68.6 bits (166), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 45/126 (35%), Positives = 67/126 (53%), Gaps = 1/126 (0%)
Frame = +1
Query: 729 PPLVKTQTVTISDNANAVKSEIPTKDVPIVHTETKTITYEAAQTDDNSGDLDPGVLLTAX 788
PP V T++V + V +PTK+VP+V TET+T+TYE + D + GVL++A
Sbjct: 115 PPTVATESVHYQPDVEEVP--VPTKNVPLVKTETRTVTYER---EGFPFDGEDGVLVSAS 279
Query: 789 XXXXXXXXXXXXXXXXXXVKGGISETRIEKRIVITG-DADIDHDQVLVQAIKEAKEQHPD 847
K G+ ETR+E R+V++ D D D+D L AI+ E +PD
Sbjct: 280 SHSTRMQTIETTTYKTE--KDGVQETRVEHRVVLSSTDDDFDYDAALADAIRSVTEFNPD 453
Query: 848 MSVTKV 853
MSV ++
Sbjct: 454 MSVERI 471
>03469
Length = 1275
Score = 65.5 bits (158), Expect = 8e-11, Method: Compositional matrix adjust.
Identities = 43/116 (37%), Positives = 63/116 (54%), Gaps = 2/116 (1%)
Frame = -3
Query: 750 IPTKDVPIVHTETKTITYEAAQTDDNSGDLDPGVLLTAXXXXXXXXXXXXXXXXXXXVKG 809
+PTK+VP+V TET+T+TYE + D + GVL++A K
Sbjct: 1258 VPTKNVPLVKTETRTVTYER---EGFPFDGEDGVLVSASSHSTRMQTIETTTYKTE--KD 1094
Query: 810 GISETRIEKRIVITG-DADIDHDQVLVQAIKEAKEQHPDMSVTKV-VVHQETEIAD 863
G+ ETR+E R+V++ D D D+D L AI+ E +PDMSV ++ V Q E+ D
Sbjct: 1093 GVQETRVEHRVVLSSTDDDFDYDAALADAIRSVTEFNPDMSVERIECVQQIEEVKD 926
>05888
Length = 490
Score = 49.7 bits (117), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 22/36 (61%), Positives = 26/36 (72%)
Frame = -2
Query: 503 LGSKFRYSGRTQAQTRQASALIDRPAPHFERTASKR 538
LGSKFRYSGRT Q R +S +DRP P+FER+ R
Sbjct: 489 LGSKFRYSGRTLYQARHSSQTLDRPDPYFERSQPAR 382
>12829
Length = 2357
Score = 32.0 bits (71), Expect = 0.96, Method: Compositional matrix adjust.
Identities = 14/40 (35%), Positives = 24/40 (60%)
Frame = -2
Query: 124 EEIILKAPIAAPEPELKTDPSLDLHSLSSAETQPAQEELR 163
EEI+L +P+A+P+P+ PS+ + + S Q A+ R
Sbjct: 1669 EEIVLVSPLASPQPDFPMSPSVSVLGVPSPRIQTARSPSR 1550
>20292
Length = 1014
Score = 30.8 bits (68), Expect = 2.5, Method: Compositional matrix adjust.
Identities = 18/48 (37%), Positives = 23/48 (47%)
Frame = +3
Query: 214 VSLLDDTVYECVVEKHAKGQDLLKRVCEHLNLLEEDYFGLAIWDNATS 261
SLL D YEC +E H Q +L E ++ L GL + N TS
Sbjct: 567 FSLLQDVSYECCIEVHGPRQTIL----EAMSHLTSKDTGLTLAANGTS 698
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000381839 | hsapiens_gene_ensembl | Protein 4.1
(Band 4.1) (P4.1) (EPB4.1) (4.1R).
[Source:Uniprot/SWISSPROT;Acc:P11171]
(767 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
00990 386 e-107
18811 187 2e-47
11374 177 2e-44
17332 145 7e-35
13951 55 6e-17
28244 79 1e-14
05888 49 6e-06
03469 47 4e-05
08363 45 8e-05
12829 32 0.81
20292 31 2.1
>00990
Length = 3161
Score = 386 bits (991), Expect = e-107, Method: Compositional matrix adjust.
Identities = 187/363 (51%), Positives = 258/363 (71%), Gaps = 5/363 (1%)
Frame = +3
Query: 183 EVKEESPQSKAETELKASQKPIRKHRNMHCKVSLLDDTVYECVVEKHAKGQDLLKRVCEH 242
EV EES + + K+ QK R + + +V LLD ++++A+G++L +VC+H
Sbjct: 180 EV*EESQ*NGRQDGSKSPQKQ-RTGKGFNYEVVLLDGEHVNFELDRNAEGRELFDKVCQH 356
Query: 243 LNLLEEDYFGLAIWDNATS---KTWLDSAKEIKKQVRGVPWNFTFNVKFYPPDPAQLTED 299
L+L+E+DYFGL D S K WL K I KQ +G PW F F +KFYPPDP QL E
Sbjct: 357 LDLIEKDYFGLQFVDERISNHLKCWLSPDKRISKQKKGGPWLFDFALKFYPPDPTQLRES 536
Query: 300 ITRYYLCLQLRQDIVAGRLPCSFATLALLGSYTIQSELGDYDPELH-GVDYVSDFKLAPN 358
+TR+ + LQ R+DI++G+LP ++ T A+LGSY +Q+++GDYDP H GV+Y+ D APN
Sbjct: 537 LTRWLVVLQTRRDILSGKLPATYLTQAMLGSYCVQADVGDYDPNEHRGVEYIRDTPFAPN 716
Query: 359 QTKELEEKVMELHKSYRSMTPAQADLEFLENAKKLSMYGVDLHKAKDLEGVDIILGVCSS 418
QT +L EK++ELH+ ++ TP +A+ FLENAKKL+MYGVDLH A+D+ VDI+LGVC+S
Sbjct: 717 QTIDLLEKIVELHRQHKGQTPDEAETNFLENAKKLAMYGVDLHAAQDVNNVDIMLGVCAS 896
Query: 419 GLLVYKDKLRINRFPWPKVLKISYKRSSFFIKIRPGEQEQYESTIGFKLPSYRAAKKLWK 478
GL VY++KLRI+RF WPK+LKISYKR F+IK+RP + E++ FKL ++R AK+LWK
Sbjct: 897 GLQVYREKLRISRFVWPKILKISYKRRQFYIKVRPSDNSAMENSFCFKLATHRLAKRLWK 1076
Query: 479 VCVEHHTFFRLTSTD-TIPKSKFLALGSKFRYSGRTQAQTRQASALIDRPAPHFERTASK 537
+CVEHH FFRL + + + F LGSKFRYSGRT QTRQ+S ++DRP P+FER+
Sbjct: 1077ICVEHHAFFRLREAEQSQNAAMFPRLGSKFRYSGRTLYQTRQSSQILDRPNPYFERSQPA 1256
Query: 538 RAS 540
R+S
Sbjct: 1257RSS 1265
Score = 41.6 bits (96), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 21/55 (38%), Positives = 33/55 (60%), Gaps = 2/55 (3%)
Frame = +3
Query: 711 KGGISETRIEKRIVITG--DADIDHDQVLVQAIKEAKEQHPDMSVTKVVVHQETE 763
K GI TR+E ++V++ D + D+D L AI+ E +PDMSV ++ Q+ E
Sbjct: 2145 KDGIQHTRVEHKVVLSSADDEEFDYDAALADAIRSVTEFNPDMSVERIECVQQIE 2309
>18811
Length = 478
Score = 187 bits (474), Expect = 2e-47, Method: Compositional matrix adjust.
Identities = 79/134 (58%), Positives = 108/134 (80%)
Frame = -2
Query: 345 HGVDYVSDFKLAPNQTKELEEKVMELHKSYRSMTPAQADLEFLENAKKLSMYGVDLHKAK 404
HG DY+ D APNQ EL EK++ELH+ ++ TP +A++ +LENAKKLSMYGVDLH A+
Sbjct: 402 HGADYIKDIPFAPNQAPELLEKIVELHRQHKGQTPDEAEVNYLENAKKLSMYGVDLHAAQ 223
Query: 405 DLEGVDIILGVCSSGLLVYKDKLRINRFPWPKVLKISYKRSSFFIKIRPGEQEQYESTIG 464
D+ VDI+LGVCSSGL VY+DKLRI+RF WPK++KISYKR F++K+RP + + E+++
Sbjct: 222 DVNNVDIMLGVCSSGLQVYRDKLRISRFVWPKIIKISYKRKHFYVKVRPADNKGLETSVS 43
Query: 465 FKLPSYRAAKKLWK 478
F+LP++R AK+LWK
Sbjct: 42 FRLPTHRLAKRLWK 1
>11374
Length = 800
Score = 177 bits (448), Expect = 2e-44, Method: Compositional matrix adjust.
Identities = 80/140 (57%), Positives = 104/140 (74%), Gaps = 1/140 (0%)
Frame = +3
Query: 400 LHKAKDLEGVDIILGVCSSGLLVYKDKLRINRFPWPKVLKISYKRSSFFIKIRPGEQEQY 459
LH A+D+ VDI+LGVC+SGL VY++KLRI+RF WPK+LKISYKR F+IK+RP +
Sbjct: 3 LHAAQDVNNVDIMLGVCASGLQVYREKLRISRFVWPKILKISYKRRQFYIKVRPSDNSAM 182
Query: 460 ESTIGFKLPSYRAAKKLWKVCVEHHTFFRLTSTD-TIPKSKFLALGSKFRYSGRTQAQTR 518
E++ FKL ++R AK+LWK+CVEHH FFRL + + + F LGSKFRYSGRT QTR
Sbjct: 183 ENSFCFKLATHRLAKRLWKICVEHHAFFRLREAEQSQNAAMFPRLGSKFRYSGRTLYQTR 362
Query: 519 QASALIDRPAPHFERTASKR 538
+S +DRP P+FER+ R
Sbjct: 363 HSSQTLDRPDPYFERSQPAR 422
>17332
Length = 473
Score = 145 bits (365), Expect = 7e-35, Method: Compositional matrix adjust.
Identities = 74/157 (47%), Positives = 100/157 (63%), Gaps = 2/157 (1%)
Frame = +2
Query: 218 DDTVYECVVEKHAKGQDLLKRVCEHLNLLEEDYFGLAIWDNATSKTWLDSAKEIKKQVRG 277
DD+ ++ V+ + KG L ++VCE LNL E+DYFGL D + WLD K + Q++G
Sbjct: 2 DDSDHQLQVKGNWKGILLQEKVCELLNLHEKDYFGLRFIDASGQTHWLDGNKSLSSQLKG 181
Query: 278 V--PWNFTFNVKFYPPDPAQLTEDITRYYLCLQLRQDIVAGRLPCSFATLALLGSYTIQS 335
P F VKFY DP +L E+ITRY LQ++QDI+ GRLP +F + L +Y +QS
Sbjct: 182 CQTPHKLYFGVKFYAADPCKLREEITRYLFFLQVKQDILQGRLPVTFDEASELCAYAVQS 361
Query: 336 ELGDYDPELHGVDYVSDFKLAPNQTKELEEKVMELHK 372
ELGD+DP H YVS+F PNQT+ELE +V LH+
Sbjct: 362 ELGDFDPRQHTDGYVSEFCFIPNQTEELERRVAGLHR 472
>13951
Length = 720
Score = 54.7 bits (130), Expect(2) = 6e-17, Method: Compositional matrix adjust.
Identities = 35/92 (38%), Positives = 53/92 (57%), Gaps = 4/92 (4%)
Frame = -2
Query: 186 EESPQSKAE-TELKASQKPIRKHRNMHCKVSLLDDTVYECVVEKHAKGQDLLKRVCEHLN 244
E+SP + TE K+ QK R + + +V LLD ++++A+G++L +VC+HL+
Sbjct: 464 EKSPSEMGDKTEDKSPQKQ-RTGKGFNYEVVLLDGEHVNFELDRNAEGRELFDKVCQHLD 288
Query: 245 LLEEDYFGLAIWDNATS---KTWLDSAKEIKK 273
L+E+DYFGL D S K WL K I K
Sbjct: 287 LIEKDYFGLQFVDERISNHLKCWLSPDKRISK 192
Score = 51.2 bits (121), Expect(2) = 6e-17, Method: Composition-based stats.
Identities = 23/50 (46%), Positives = 31/50 (62%)
Frame = -1
Query: 269 KEIKKQVRGVPWNFTFNVKFYPPDPAQLTEDITRYYLCLQLRQDIVAGRL 318
K+ + + +G PW F F +KFYPPDP QL E +TR+ + L VAG L
Sbjct: 204 KDFQNRKKGGPWLFDFALKFYPPDPTQLRESLTRWLVVLH-----VAGEL 70
>28244
Length = 422
Score = 78.6 bits (192), Expect = 1e-14, Method: Composition-based stats.
Identities = 47/124 (37%), Positives = 67/124 (54%), Gaps = 4/124 (3%)
Frame = -1
Query: 421 LVYKDKLRINRFPWPKVLKISYKRSSF-FIKIRPGEQEQYESTIG-FKLPSYRAAKKLWK 478
LV++ +I F WPK+ ++ +K + + E Q + I F+L S +A K LWK
Sbjct: 422 LVFEGNXKIGLFFWPKMTRLDFKGKKLTLVAVEDDENGQSQDHIFVFRLQSEKACKHLWK 243
Query: 479 VCVEHHTFFRLTSTDTIPKSK--FLALGSKFRYSGRTQAQTRQASALIDRPAPHFERTAS 536
VEHH FFRL P ++ F +GS+FRYSGRT+ QT + R + FER S
Sbjct: 242 CAVEHHAFFRLKGPVQGPNARQNFFRMGSRFRYSGRTEYQTSTMNRA--RRSVKFERKPS 69
Query: 537 KRAS 540
+R S
Sbjct: 68 QRYS 57
>05888
Length = 490
Score = 49.3 bits (116), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 22/36 (61%), Positives = 26/36 (72%)
Frame = -2
Query: 503 LGSKFRYSGRTQAQTRQASALIDRPAPHFERTASKR 538
LGSKFRYSGRT Q R +S +DRP P+FER+ R
Sbjct: 489 LGSKFRYSGRTLYQARHSSQTLDRPDPYFERSQPAR 382
>03469
Length = 1275
Score = 46.6 bits (109), Expect = 4e-05, Method: Compositional matrix adjust.
Identities = 25/58 (43%), Positives = 36/58 (62%), Gaps = 2/58 (3%)
Frame = -3
Query: 711 KGGISETRIEKRIVITG-DADIDHDQVLVQAIKEAKEQHPDMSVTKV-VVHQETEIAD 766
K G+ ETR+E R+V++ D D D+D L AI+ E +PDMSV ++ V Q E+ D
Sbjct: 1099 KDGVQETRVEHRVVLSSTDDDFDYDAALADAIRSVTEFNPDMSVERIECVQQIEEVKD 926
>08363
Length = 1878
Score = 45.4 bits (106), Expect = 8e-05, Method: Compositional matrix adjust.
Identities = 21/47 (44%), Positives = 31/47 (65%), Gaps = 1/47 (2%)
Frame = +1
Query: 711 KGGISETRIEKRIVITG-DADIDHDQVLVQAIKEAKEQHPDMSVTKV 756
K G+ ETR+E R+V++ D D D+D L AI+ E +PDMSV ++
Sbjct: 331 KDGVQETRVEHRVVLSSTDDDFDYDAALADAIRSVTEFNPDMSVERI 471
>12829
Length = 2357
Score = 32.3 bits (72), Expect = 0.81, Method: Compositional matrix adjust.
Identities = 14/40 (35%), Positives = 24/40 (60%)
Frame = -2
Query: 124 EEIILKAPIAAPEPELKTDPSLDLHSLSSAETQPAQEELR 163
EEI+L +P+A+P+P+ PS+ + + S Q A+ R
Sbjct: 1669 EEIVLVSPLASPQPDFPMSPSVSVLGVPSPRIQTARSPSR 1550
>20292
Length = 1014
Score = 30.8 bits (68), Expect = 2.1, Method: Compositional matrix adjust.
Identities = 18/47 (38%), Positives = 23/47 (48%)
Frame = +3
Query: 215 SLLDDTVYECVVEKHAKGQDLLKRVCEHLNLLEEDYFGLAIWDNATS 261
SLL D YEC +E H Q +L E ++ L GL + N TS
Sbjct: 570 SLLQDVSYECCIEVHGPRQTIL----EAMSHLTSKDTGLTLAANGTS 698
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000381841 | hsapiens_gene_ensembl | Protein 4.1
(Band 4.1) (P4.1) (EPB4.1) (4.1R).
[Source:Uniprot/SWISSPROT;Acc:P11171]
(850 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
00990 386 e-107
18811 187 2e-47
11374 177 2e-44
17332 145 6e-35
13951 55 4e-17
28244 79 8e-15
08363 68 1e-11
03469 65 8e-11
05888 49 6e-06
12829 32 0.95
20292 31 2.5
>00990
Length = 3161
Score = 386 bits (992), Expect = e-107, Method: Compositional matrix adjust.
Identities = 187/363 (51%), Positives = 258/363 (71%), Gaps = 5/363 (1%)
Frame = +3
Query: 183 EVKEESPQSKAETELKASQKPIRKHRNMHCKVSLLDDTVYECVVEKHAKGQDLLKRVCEH 242
EV EES + + K+ QK R + + +V LLD ++++A+G++L +VC+H
Sbjct: 180 EV*EESQ*NGRQDGSKSPQKQ-RTGKGFNYEVVLLDGEHVNFELDRNAEGRELFDKVCQH 356
Query: 243 LNLLEEDYFGLAIWDNATS---KTWLDSAKEIKKQVRGVPWNFTFNVKFYPPDPAQLTED 299
L+L+E+DYFGL D S K WL K I KQ +G PW F F +KFYPPDP QL E
Sbjct: 357 LDLIEKDYFGLQFVDERISNHLKCWLSPDKRISKQKKGGPWLFDFALKFYPPDPTQLRES 536
Query: 300 ITRYYLCLQLRQDIVAGRLPCSFATLALLGSYTIQSELGDYDPELH-GVDYVSDFKLAPN 358
+TR+ + LQ R+DI++G+LP ++ T A+LGSY +Q+++GDYDP H GV+Y+ D APN
Sbjct: 537 LTRWLVVLQTRRDILSGKLPATYLTQAMLGSYCVQADVGDYDPNEHRGVEYIRDTPFAPN 716
Query: 359 QTKELEEKVMELHKSYRSMTPAQADLEFLENAKKLSMYGVDLHKAKDLEGVDIILGVCSS 418
QT +L EK++ELH+ ++ TP +A+ FLENAKKL+MYGVDLH A+D+ VDI+LGVC+S
Sbjct: 717 QTIDLLEKIVELHRQHKGQTPDEAETNFLENAKKLAMYGVDLHAAQDVNNVDIMLGVCAS 896
Query: 419 GLLVYKDKLRINRFPWPKVLKISYKRSSFFIKIRPGEQEQYESTIGFKLPSYRAAKKLWK 478
GL VY++KLRI+RF WPK+LKISYKR F+IK+RP + E++ FKL ++R AK+LWK
Sbjct: 897 GLQVYREKLRISRFVWPKILKISYKRRQFYIKVRPSDNSAMENSFCFKLATHRLAKRLWK 1076
Query: 479 VCVEHHTFFRLTSTD-TIPKSKFLALGSKFRYSGRTQAQTRQASALIDRPAPHFERTASK 537
+CVEHH FFRL + + + F LGSKFRYSGRT QTRQ+S ++DRP P+FER+
Sbjct: 1077ICVEHHAFFRLREAEQSQNAAMFPRLGSKFRYSGRTLYQTRQSSQILDRPNPYFERSQPA 1256
Query: 538 RAS 540
R+S
Sbjct: 1257RSS 1265
Score = 41.6 bits (96), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 21/55 (38%), Positives = 33/55 (60%), Gaps = 2/55 (3%)
Frame = +3
Query: 794 KGGISETRIEKRIVITG--DADIDHDQVLVQAIKEAKEQHPDMSVTKVVVHQETE 846
K GI TR+E ++V++ D + D+D L AI+ E +PDMSV ++ Q+ E
Sbjct: 2145 KDGIQHTRVEHKVVLSSADDEEFDYDAALADAIRSVTEFNPDMSVERIECVQQIE 2309
>18811
Length = 478
Score = 187 bits (474), Expect = 2e-47, Method: Compositional matrix adjust.
Identities = 79/134 (58%), Positives = 108/134 (80%)
Frame = -2
Query: 345 HGVDYVSDFKLAPNQTKELEEKVMELHKSYRSMTPAQADLEFLENAKKLSMYGVDLHKAK 404
HG DY+ D APNQ EL EK++ELH+ ++ TP +A++ +LENAKKLSMYGVDLH A+
Sbjct: 402 HGADYIKDIPFAPNQAPELLEKIVELHRQHKGQTPDEAEVNYLENAKKLSMYGVDLHAAQ 223
Query: 405 DLEGVDIILGVCSSGLLVYKDKLRINRFPWPKVLKISYKRSSFFIKIRPGEQEQYESTIG 464
D+ VDI+LGVCSSGL VY+DKLRI+RF WPK++KISYKR F++K+RP + + E+++
Sbjct: 222 DVNNVDIMLGVCSSGLQVYRDKLRISRFVWPKIIKISYKRKHFYVKVRPADNKGLETSVS 43
Query: 465 FKLPSYRAAKKLWK 478
F+LP++R AK+LWK
Sbjct: 42 FRLPTHRLAKRLWK 1
>11374
Length = 800
Score = 177 bits (449), Expect = 2e-44, Method: Compositional matrix adjust.
Identities = 80/140 (57%), Positives = 104/140 (74%), Gaps = 1/140 (0%)
Frame = +3
Query: 400 LHKAKDLEGVDIILGVCSSGLLVYKDKLRINRFPWPKVLKISYKRSSFFIKIRPGEQEQY 459
LH A+D+ VDI+LGVC+SGL VY++KLRI+RF WPK+LKISYKR F+IK+RP +
Sbjct: 3 LHAAQDVNNVDIMLGVCASGLQVYREKLRISRFVWPKILKISYKRRQFYIKVRPSDNSAM 182
Query: 460 ESTIGFKLPSYRAAKKLWKVCVEHHTFFRLTSTD-TIPKSKFLALGSKFRYSGRTQAQTR 518
E++ FKL ++R AK+LWK+CVEHH FFRL + + + F LGSKFRYSGRT QTR
Sbjct: 183 ENSFCFKLATHRLAKRLWKICVEHHAFFRLREAEQSQNAAMFPRLGSKFRYSGRTLYQTR 362
Query: 519 QASALIDRPAPHFERTASKR 538
+S +DRP P+FER+ R
Sbjct: 363 HSSQTLDRPDPYFERSQPAR 422
>17332
Length = 473
Score = 145 bits (366), Expect = 6e-35, Method: Compositional matrix adjust.
Identities = 74/157 (47%), Positives = 100/157 (63%), Gaps = 2/157 (1%)
Frame = +2
Query: 218 DDTVYECVVEKHAKGQDLLKRVCEHLNLLEEDYFGLAIWDNATSKTWLDSAKEIKKQVRG 277
DD+ ++ V+ + KG L ++VCE LNL E+DYFGL D + WLD K + Q++G
Sbjct: 2 DDSDHQLQVKGNWKGILLQEKVCELLNLHEKDYFGLRFIDASGQTHWLDGNKSLSSQLKG 181
Query: 278 V--PWNFTFNVKFYPPDPAQLTEDITRYYLCLQLRQDIVAGRLPCSFATLALLGSYTIQS 335
P F VKFY DP +L E+ITRY LQ++QDI+ GRLP +F + L +Y +QS
Sbjct: 182 CQTPHKLYFGVKFYAADPCKLREEITRYLFFLQVKQDILQGRLPVTFDEASELCAYAVQS 361
Query: 336 ELGDYDPELHGVDYVSDFKLAPNQTKELEEKVMELHK 372
ELGD+DP H YVS+F PNQT+ELE +V LH+
Sbjct: 362 ELGDFDPRQHTDGYVSEFCFIPNQTEELERRVAGLHR 472
>13951
Length = 720
Score = 55.1 bits (131), Expect(2) = 4e-17, Method: Compositional matrix adjust.
Identities = 35/92 (38%), Positives = 53/92 (57%), Gaps = 4/92 (4%)
Frame = -2
Query: 186 EESPQSKAE-TELKASQKPIRKHRNMHCKVSLLDDTVYECVVEKHAKGQDLLKRVCEHLN 244
E+SP + TE K+ QK R + + +V LLD ++++A+G++L +VC+HL+
Sbjct: 464 EKSPSEMGDKTEDKSPQKQ-RTGKGFNYEVVLLDGEHVNFELDRNAEGRELFDKVCQHLD 288
Query: 245 LLEEDYFGLAIWDNATS---KTWLDSAKEIKK 273
L+E+DYFGL D S K WL K I K
Sbjct: 287 LIEKDYFGLQFVDERISNHLKCWLSPDKRISK 192
Score = 51.6 bits (122), Expect(2) = 4e-17, Method: Composition-based stats.
Identities = 23/50 (46%), Positives = 31/50 (62%)
Frame = -1
Query: 269 KEIKKQVRGVPWNFTFNVKFYPPDPAQLTEDITRYYLCLQLRQDIVAGRL 318
K+ + + +G PW F F +KFYPPDP QL E +TR+ + L VAG L
Sbjct: 204 KDFQNRKKGGPWLFDFALKFYPPDPTQLRESLTRWLVVLH-----VAGEL 70
>28244
Length = 422
Score = 79.0 bits (193), Expect = 8e-15, Method: Composition-based stats.
Identities = 47/124 (37%), Positives = 67/124 (54%), Gaps = 4/124 (3%)
Frame = -1
Query: 421 LVYKDKLRINRFPWPKVLKISYKRSSF-FIKIRPGEQEQYESTIG-FKLPSYRAAKKLWK 478
LV++ +I F WPK+ ++ +K + + E Q + I F+L S +A K LWK
Sbjct: 422 LVFEGNXKIGLFFWPKMTRLDFKGKKLTLVAVEDDENGQSQDHIFVFRLQSEKACKHLWK 243
Query: 479 VCVEHHTFFRLTSTDTIPKSK--FLALGSKFRYSGRTQAQTRQASALIDRPAPHFERTAS 536
VEHH FFRL P ++ F +GS+FRYSGRT+ QT + R + FER S
Sbjct: 242 CAVEHHAFFRLKGPVQGPNARQNFFRMGSRFRYSGRTEYQTSTMNRA--RRSVKFERKPS 69
Query: 537 KRAS 540
+R S
Sbjct: 68 QRYS 57
>08363
Length = 1878
Score = 68.2 bits (165), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 45/126 (35%), Positives = 67/126 (53%), Gaps = 1/126 (0%)
Frame = +1
Query: 715 PPLVKTQTVTISDNANAVKSEIPTKDVPIVHTETKTITYEAAQTDDNSGDLDPGVLLTAX 774
PP V T++V + V +PTK+VP+V TET+T+TYE + D + GVL++A
Sbjct: 115 PPTVATESVHYQPDVEEVP--VPTKNVPLVKTETRTVTYER---EGFPFDGEDGVLVSAS 279
Query: 775 XXXXXXXXXXXXXXXXXXVKGGISETRIEKRIVITG-DADIDHDQVLVQAIKEAKEQHPD 833
K G+ ETR+E R+V++ D D D+D L AI+ E +PD
Sbjct: 280 SHSTRMQTIETTTYKTE--KDGVQETRVEHRVVLSSTDDDFDYDAALADAIRSVTEFNPD 453
Query: 834 MSVTKV 839
MSV ++
Sbjct: 454 MSVERI 471
>03469
Length = 1275
Score = 65.5 bits (158), Expect = 8e-11, Method: Compositional matrix adjust.
Identities = 43/116 (37%), Positives = 63/116 (54%), Gaps = 2/116 (1%)
Frame = -3
Query: 736 IPTKDVPIVHTETKTITYEAAQTDDNSGDLDPGVLLTAXXXXXXXXXXXXXXXXXXXVKG 795
+PTK+VP+V TET+T+TYE + D + GVL++A K
Sbjct: 1258 VPTKNVPLVKTETRTVTYER---EGFPFDGEDGVLVSASSHSTRMQTIETTTYKTE--KD 1094
Query: 796 GISETRIEKRIVITG-DADIDHDQVLVQAIKEAKEQHPDMSVTKV-VVHQETEIAD 849
G+ ETR+E R+V++ D D D+D L AI+ E +PDMSV ++ V Q E+ D
Sbjct: 1093 GVQETRVEHRVVLSSTDDDFDYDAALADAIRSVTEFNPDMSVERIECVQQIEEVKD 926
>05888
Length = 490
Score = 49.3 bits (116), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 22/36 (61%), Positives = 26/36 (72%)
Frame = -2
Query: 503 LGSKFRYSGRTQAQTRQASALIDRPAPHFERTASKR 538
LGSKFRYSGRT Q R +S +DRP P+FER+ R
Sbjct: 489 LGSKFRYSGRTLYQARHSSQTLDRPDPYFERSQPAR 382
>12829
Length = 2357
Score = 32.0 bits (71), Expect = 0.95, Method: Compositional matrix adjust.
Identities = 14/40 (35%), Positives = 24/40 (60%)
Frame = -2
Query: 124 EEIILKAPIAAPEPELKTDPSLDLHSLSSAETQPAQEELR 163
EEI+L +P+A+P+P+ PS+ + + S Q A+ R
Sbjct: 1669 EEIVLVSPLASPQPDFPMSPSVSVLGVPSPRIQTARSPSR 1550
>20292
Length = 1014
Score = 30.8 bits (68), Expect = 2.5, Method: Compositional matrix adjust.
Identities = 18/48 (37%), Positives = 23/48 (47%)
Frame = +3
Query: 214 VSLLDDTVYECVVEKHAKGQDLLKRVCEHLNLLEEDYFGLAIWDNATS 261
SLL D YEC +E H Q +L E ++ L GL + N TS
Sbjct: 567 FSLLQDVSYECCIEVHGPRQTIL----EAMSHLTSKDTGLTLAANGTS 698
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000317597 | hsapiens_gene_ensembl | Protein 4.1
(Band 4.1) (P4.1) (EPB4.1) (4.1R).
[Source:Uniprot/SWISSPROT;Acc:P11171]
(641 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
00990 380 e-106
18811 186 2e-47
11374 176 3e-44
17332 147 2e-35
28244 79 4e-15
13951 50 8e-15
08363 68 1e-11
03469 65 7e-11
05888 49 6e-06
20292 31 1.8
17496 31 1.8
>00990
Length = 3161
Score = 380 bits (977), Expect = e-106, Method: Compositional matrix adjust.
Identities = 178/336 (52%), Positives = 245/336 (72%), Gaps = 5/336 (1%)
Frame = +3
Query: 1 MHCKVSLLDDTVYECVVEKHAKGQDLLKRVCEHLNLLEEDYFGLAIWDNATS---KTWLD 57
+ +V LLD ++++A+G++L +VC+HL+L+E+DYFGL D S K WL
Sbjct: 258 FNYEVVLLDGEHVNFELDRNAEGRELFDKVCQHLDLIEKDYFGLQFVDERISNHLKCWLS 437
Query: 58 SAKEIKKQVRGVPWNFTFNVKFYPPDPAQLTEDITRYYLCLQLRQDIVAGRLPCSFATLA 117
K I KQ +G PW F F +KFYPPDP QL E +TR+ + LQ R+DI++G+LP ++ T A
Sbjct: 438 PDKRISKQKKGGPWLFDFALKFYPPDPTQLRESLTRWLVVLQTRRDILSGKLPATYLTQA 617
Query: 118 LLGSYTIQSELGDYDPELH-GVDYVSDFKLAPNQTKELEEKVMELHKSYRSMTPAQADLE 176
+LGSY +Q+++GDYDP H GV+Y+ D APNQT +L EK++ELH+ ++ TP +A+
Sbjct: 618 MLGSYCVQADVGDYDPNEHRGVEYIRDTPFAPNQTIDLLEKIVELHRQHKGQTPDEAETN 797
Query: 177 FLENAKKLSMYGVDLHKAKDLEGVDIILGVCSSGLLVYKDKLRINRFPWPKVLKISYKRS 236
FLENAKKL+MYGVDLH A+D+ VDI+LGVC+SGL VY++KLRI+RF WPK+LKISYKR
Sbjct: 798 FLENAKKLAMYGVDLHAAQDVNNVDIMLGVCASGLQVYREKLRISRFVWPKILKISYKRR 977
Query: 237 SFFIKIRPGEQEQYESTIGFKLPSYRAAKKLWKVCVEHHTFFRLTSTD-TIPKSKFLALG 295
F+IK+RP + E++ FKL ++R AK+LWK+CVEHH FFRL + + + F LG
Sbjct: 978 QFYIKVRPSDNSAMENSFCFKLATHRLAKRLWKICVEHHAFFRLREAEQSQNAAMFPRLG 1157
Query: 296 SKFRYSGRTQAQTRQASALIDRPAPHFERTASKRAS 331
SKFRYSGRT QTRQ+S ++DRP P+FER+ R+S
Sbjct: 1158SKFRYSGRTLYQTRQSSQILDRPNPYFERSQPARSS 1265
Score = 42.0 bits (97), Expect = 8e-04, Method: Compositional matrix adjust.
Identities = 21/55 (38%), Positives = 33/55 (60%), Gaps = 2/55 (3%)
Frame = +3
Query: 585 KGGISETRIEKRIVITG--DADIDHDQVLVQAIKEAKEQHPDMSVTKVVVHQETE 637
K GI TR+E ++V++ D + D+D L AI+ E +PDMSV ++ Q+ E
Sbjct: 2145 KDGIQHTRVEHKVVLSSADDEEFDYDAALADAIRSVTEFNPDMSVERIECVQQIE 2309
>18811
Length = 478
Score = 186 bits (473), Expect = 2e-47, Method: Compositional matrix adjust.
Identities = 79/134 (58%), Positives = 108/134 (80%)
Frame = -2
Query: 136 HGVDYVSDFKLAPNQTKELEEKVMELHKSYRSMTPAQADLEFLENAKKLSMYGVDLHKAK 195
HG DY+ D APNQ EL EK++ELH+ ++ TP +A++ +LENAKKLSMYGVDLH A+
Sbjct: 402 HGADYIKDIPFAPNQAPELLEKIVELHRQHKGQTPDEAEVNYLENAKKLSMYGVDLHAAQ 223
Query: 196 DLEGVDIILGVCSSGLLVYKDKLRINRFPWPKVLKISYKRSSFFIKIRPGEQEQYESTIG 255
D+ VDI+LGVCSSGL VY+DKLRI+RF WPK++KISYKR F++K+RP + + E+++
Sbjct: 222 DVNNVDIMLGVCSSGLQVYRDKLRISRFVWPKIIKISYKRKHFYVKVRPADNKGLETSVS 43
Query: 256 FKLPSYRAAKKLWK 269
F+LP++R AK+LWK
Sbjct: 42 FRLPTHRLAKRLWK 1
>11374
Length = 800
Score = 176 bits (445), Expect = 3e-44, Method: Compositional matrix adjust.
Identities = 80/140 (57%), Positives = 104/140 (74%), Gaps = 1/140 (0%)
Frame = +3
Query: 191 LHKAKDLEGVDIILGVCSSGLLVYKDKLRINRFPWPKVLKISYKRSSFFIKIRPGEQEQY 250
LH A+D+ VDI+LGVC+SGL VY++KLRI+RF WPK+LKISYKR F+IK+RP +
Sbjct: 3 LHAAQDVNNVDIMLGVCASGLQVYREKLRISRFVWPKILKISYKRRQFYIKVRPSDNSAM 182
Query: 251 ESTIGFKLPSYRAAKKLWKVCVEHHTFFRLTSTD-TIPKSKFLALGSKFRYSGRTQAQTR 309
E++ FKL ++R AK+LWK+CVEHH FFRL + + + F LGSKFRYSGRT QTR
Sbjct: 183 ENSFCFKLATHRLAKRLWKICVEHHAFFRLREAEQSQNAAMFPRLGSKFRYSGRTLYQTR 362
Query: 310 QASALIDRPAPHFERTASKR 329
+S +DRP P+FER+ R
Sbjct: 363 HSSQTLDRPDPYFERSQPAR 422
>17332
Length = 473
Score = 147 bits (370), Expect = 2e-35, Method: Composition-based stats.
Identities = 74/157 (47%), Positives = 100/157 (63%), Gaps = 2/157 (1%)
Frame = +2
Query: 9 DDTVYECVVEKHAKGQDLLKRVCEHLNLLEEDYFGLAIWDNATSKTWLDSAKEIKKQVRG 68
DD+ ++ V+ + KG L ++VCE LNL E+DYFGL D + WLD K + Q++G
Sbjct: 2 DDSDHQLQVKGNWKGILLQEKVCELLNLHEKDYFGLRFIDASGQTHWLDGNKSLSSQLKG 181
Query: 69 --VPWNFTFNVKFYPPDPAQLTEDITRYYLCLQLRQDIVAGRLPCSFATLALLGSYTIQS 126
P F VKFY DP +L E+ITRY LQ++QDI+ GRLP +F + L +Y +QS
Sbjct: 182 CQTPHKLYFGVKFYAADPCKLREEITRYLFFLQVKQDILQGRLPVTFDEASELCAYAVQS 361
Query: 127 ELGDYDPELHGVDYVSDFKLAPNQTKELEEKVMELHK 163
ELGD+DP H YVS+F PNQT+ELE +V LH+
Sbjct: 362 ELGDFDPRQHTDGYVSEFCFIPNQTEELERRVAGLHR 472
>28244
Length = 422
Score = 79.3 bits (194), Expect = 4e-15, Method: Composition-based stats.
Identities = 47/124 (37%), Positives = 67/124 (54%), Gaps = 4/124 (3%)
Frame = -1
Query: 212 LVYKDKLRINRFPWPKVLKISYKRSSF-FIKIRPGEQEQYESTIG-FKLPSYRAAKKLWK 269
LV++ +I F WPK+ ++ +K + + E Q + I F+L S +A K LWK
Sbjct: 422 LVFEGNXKIGLFFWPKMTRLDFKGKKLTLVAVEDDENGQSQDHIFVFRLQSEKACKHLWK 243
Query: 270 VCVEHHTFFRLTSTDTIPKSK--FLALGSKFRYSGRTQAQTRQASALIDRPAPHFERTAS 327
VEHH FFRL P ++ F +GS+FRYSGRT+ QT + R + FER S
Sbjct: 242 CAVEHHAFFRLKGPVQGPNARQNFFRMGSRFRYSGRTEYQTSTMNRA--RRSVKFERKPS 69
Query: 328 KRAS 331
+R S
Sbjct: 68 QRYS 57
>13951
Length = 720
Score = 50.4 bits (119), Expect(2) = 8e-15, Method: Compositional matrix adjust.
Identities = 26/64 (40%), Positives = 39/64 (60%), Gaps = 3/64 (4%)
Frame = -2
Query: 4 KVSLLDDTVYECVVEKHAKGQDLLKRVCEHLNLLEEDYFGLAIWDNATS---KTWLDSAK 60
+V LLD ++++A+G++L +VC+HL+L+E+DYFGL D S K WL K
Sbjct: 383 EVVLLDGEHVNFELDRNAEGRELFDKVCQHLDLIEKDYFGLQFVDERISNHLKCWLSPDK 204
Query: 61 EIKK 64
I K
Sbjct: 203 RISK 192
Score = 48.1 bits (113), Expect(2) = 8e-15, Method: Compositional matrix adjust.
Identities = 23/50 (46%), Positives = 31/50 (62%)
Frame = -1
Query: 60 KEIKKQVRGVPWNFTFNVKFYPPDPAQLTEDITRYYLCLQLRQDIVAGRL 109
K+ + + +G PW F F +KFYPPDP QL E +TR+ + L VAG L
Sbjct: 204 KDFQNRKKGGPWLFDFALKFYPPDPTQLRESLTRWLVVLH-----VAGEL 70
>08363
Length = 1878
Score = 68.2 bits (165), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 47/133 (35%), Positives = 69/133 (51%), Gaps = 1/133 (0%)
Frame = +1
Query: 506 PPLVKTQTVTISDNANAVKSEIPTKDVPIVHTETKTITYEAAQTDDNSGDLDPGVLLTAX 565
PP V T++V + V +PTK+VP+V TET+T+TYE + D + GVL++A
Sbjct: 115 PPTVATESVHYQPDVEEVP--VPTKNVPLVKTETRTVTYER---EGFPFDGEDGVLVSAS 279
Query: 566 XXXXXXXXXXXXXXXXXXVKGGISETRIEKRIVITG-DADIDHDQVLVQAIKEAKEQHPD 624
K G+ ETR+E R+V++ D D D+D L AI+ E +PD
Sbjct: 280 SHSTRMQTIETTTYKTE--KDGVQETRVEHRVVLSSTDDDFDYDAALADAIRSVTEFNPD 453
Query: 625 MSVTKVVVHQETE 637
MSV ++ Q E
Sbjct: 454 MSVERIECVQXIE 492
>03469
Length = 1275
Score = 65.5 bits (158), Expect = 7e-11, Method: Compositional matrix adjust.
Identities = 43/116 (37%), Positives = 63/116 (54%), Gaps = 2/116 (1%)
Frame = -3
Query: 527 IPTKDVPIVHTETKTITYEAAQTDDNSGDLDPGVLLTAXXXXXXXXXXXXXXXXXXXVKG 586
+PTK+VP+V TET+T+TYE + D + GVL++A K
Sbjct: 1258 VPTKNVPLVKTETRTVTYER---EGFPFDGEDGVLVSASSHSTRMQTIETTTYKTE--KD 1094
Query: 587 GISETRIEKRIVITG-DADIDHDQVLVQAIKEAKEQHPDMSVTKV-VVHQETEIAD 640
G+ ETR+E R+V++ D D D+D L AI+ E +PDMSV ++ V Q E+ D
Sbjct: 1093 GVQETRVEHRVVLSSTDDDFDYDAALADAIRSVTEFNPDMSVERIECVQQIEEVKD 926
>05888
Length = 490
Score = 48.9 bits (115), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 22/36 (61%), Positives = 26/36 (72%)
Frame = -2
Query: 294 LGSKFRYSGRTQAQTRQASALIDRPAPHFERTASKR 329
LGSKFRYSGRT Q R +S +DRP P+FER+ R
Sbjct: 489 LGSKFRYSGRTLYQARHSSQTLDRPDPYFERSQPAR 382
>20292
Length = 1014
Score = 30.8 bits (68), Expect = 1.8, Method: Compositional matrix adjust.
Identities = 18/47 (38%), Positives = 23/47 (48%)
Frame = +3
Query: 6 SLLDDTVYECVVEKHAKGQDLLKRVCEHLNLLEEDYFGLAIWDNATS 52
SLL D YEC +E H Q +L E ++ L GL + N TS
Sbjct: 570 SLLQDVSYECCIEVHGPRQTIL----EAMSHLTSKDTGLTLAANGTS 698
>17496
Length = 461
Score = 30.8 bits (68), Expect = 1.8, Method: Compositional matrix adjust.
Identities = 15/38 (39%), Positives = 23/38 (60%), Gaps = 2/38 (5%)
Frame = +3
Query: 190 DLHKAKDLEGVDIILGVCSSGLL--VYKDKLRINRFPW 225
DLH+A+ +GV ++L SGL +K K +R+PW
Sbjct: 111 DLHRARTFQGVTLLLWETLSGLQKPGWKGKELKSRWPW 224
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000351880 | hsapiens_gene_ensembl | Protein 4.1
(Band 4.1) (P4.1) (EPB4.1) (4.1R).
[Source:Uniprot/SWISSPROT;Acc:P11171]
(588 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
00990 380 e-106
18811 186 2e-47
11374 175 4e-44
17332 146 2e-35
28244 79 6e-15
13951 50 7e-15
08363 63 3e-10
03469 60 2e-09
05888 49 6e-06
20292 31 1.3
17496 31 1.7
>00990
Length = 3161
Score = 380 bits (975), Expect = e-106, Method: Compositional matrix adjust.
Identities = 178/333 (53%), Positives = 244/333 (73%), Gaps = 5/333 (1%)
Frame = +3
Query: 4 KVSLLDDTVYECVVEKHAKGQDLLKRVCEHLNLLEEDYFGLAIWDNATS---KTWLDSAK 60
+V LLD ++++A+G++L +VC+HL+L+E+DYFGL D S K WL K
Sbjct: 267 EVVLLDGEHVNFELDRNAEGRELFDKVCQHLDLIEKDYFGLQFVDERISNHLKCWLSPDK 446
Query: 61 EIKKQVRGVPWNFTFNVKFYPPDPAQLTEDITRYYLCLQLRQDIVAGRLPCSFATLALLG 120
I KQ +G PW F F +KFYPPDP QL E +TR+ + LQ R+DI++G+LP ++ T A+LG
Sbjct: 447 RISKQKKGGPWLFDFALKFYPPDPTQLRESLTRWLVVLQTRRDILSGKLPATYLTQAMLG 626
Query: 121 SYTIQSELGDYDPELH-GVDYVSDFKLAPNQTKELEEKVMELHKSYRSMTPAQADLEFLE 179
SY +Q+++GDYDP H GV+Y+ D APNQT +L EK++ELH+ ++ TP +A+ FLE
Sbjct: 627 SYCVQADVGDYDPNEHRGVEYIRDTPFAPNQTIDLLEKIVELHRQHKGQTPDEAETNFLE 806
Query: 180 NAKKLSMYGVDLHKAKDLEGVDIILGVCSSGLLVYKDKLRINRFPWPKVLKISYKRSSFF 239
NAKKL+MYGVDLH A+D+ VDI+LGVC+SGL VY++KLRI+RF WPK+LKISYKR F+
Sbjct: 807 NAKKLAMYGVDLHAAQDVNNVDIMLGVCASGLQVYREKLRISRFVWPKILKISYKRRQFY 986
Query: 240 IKIRPGEQEQYESTIGFKLPSYRAAKKLWKVCVEHHTFFRLTSTD-TIPKSKFLALGSKF 298
IK+RP + E++ FKL ++R AK+LWK+CVEHH FFRL + + + F LGSKF
Sbjct: 987 IKVRPSDNSAMENSFCFKLATHRLAKRLWKICVEHHAFFRLREAEQSQNAAMFPRLGSKF 1166
Query: 299 RYSGRTQAQTRQASALIDRPAPHFERTASKRAS 331
RYSGRT QTRQ+S ++DRP P+FER+ R+S
Sbjct: 1167RYSGRTLYQTRQSSQILDRPNPYFERSQPARSS 1265
Score = 41.6 bits (96), Expect = 8e-04, Method: Compositional matrix adjust.
Identities = 21/55 (38%), Positives = 33/55 (60%), Gaps = 2/55 (3%)
Frame = +3
Query: 532 KGGISETRIEKRIVITG--DADIDHDQVLVQAIKEAKEQHPDMSVTKVVVHQETE 584
K GI TR+E ++V++ D + D+D L AI+ E +PDMSV ++ Q+ E
Sbjct: 2145 KDGIQHTRVEHKVVLSSADDEEFDYDAALADAIRSVTEFNPDMSVERIECVQQIE 2309
>18811
Length = 478
Score = 186 bits (473), Expect = 2e-47, Method: Compositional matrix adjust.
Identities = 79/134 (58%), Positives = 108/134 (80%)
Frame = -2
Query: 136 HGVDYVSDFKLAPNQTKELEEKVMELHKSYRSMTPAQADLEFLENAKKLSMYGVDLHKAK 195
HG DY+ D APNQ EL EK++ELH+ ++ TP +A++ +LENAKKLSMYGVDLH A+
Sbjct: 402 HGADYIKDIPFAPNQAPELLEKIVELHRQHKGQTPDEAEVNYLENAKKLSMYGVDLHAAQ 223
Query: 196 DLEGVDIILGVCSSGLLVYKDKLRINRFPWPKVLKISYKRSSFFIKIRPGEQEQYESTIG 255
D+ VDI+LGVCSSGL VY+DKLRI+RF WPK++KISYKR F++K+RP + + E+++
Sbjct: 222 DVNNVDIMLGVCSSGLQVYRDKLRISRFVWPKIIKISYKRKHFYVKVRPADNKGLETSVS 43
Query: 256 FKLPSYRAAKKLWK 269
F+LP++R AK+LWK
Sbjct: 42 FRLPTHRLAKRLWK 1
>11374
Length = 800
Score = 175 bits (444), Expect = 4e-44, Method: Compositional matrix adjust.
Identities = 80/140 (57%), Positives = 104/140 (74%), Gaps = 1/140 (0%)
Frame = +3
Query: 191 LHKAKDLEGVDIILGVCSSGLLVYKDKLRINRFPWPKVLKISYKRSSFFIKIRPGEQEQY 250
LH A+D+ VDI+LGVC+SGL VY++KLRI+RF WPK+LKISYKR F+IK+RP +
Sbjct: 3 LHAAQDVNNVDIMLGVCASGLQVYREKLRISRFVWPKILKISYKRRQFYIKVRPSDNSAM 182
Query: 251 ESTIGFKLPSYRAAKKLWKVCVEHHTFFRLTSTD-TIPKSKFLALGSKFRYSGRTQAQTR 309
E++ FKL ++R AK+LWK+CVEHH FFRL + + + F LGSKFRYSGRT QTR
Sbjct: 183 ENSFCFKLATHRLAKRLWKICVEHHAFFRLREAEQSQNAAMFPRLGSKFRYSGRTLYQTR 362
Query: 310 QASALIDRPAPHFERTASKR 329
+S +DRP P+FER+ R
Sbjct: 363 HSSQTLDRPDPYFERSQPAR 422
>17332
Length = 473
Score = 146 bits (369), Expect = 2e-35, Method: Composition-based stats.
Identities = 74/157 (47%), Positives = 100/157 (63%), Gaps = 2/157 (1%)
Frame = +2
Query: 9 DDTVYECVVEKHAKGQDLLKRVCEHLNLLEEDYFGLAIWDNATSKTWLDSAKEIKKQVRG 68
DD+ ++ V+ + KG L ++VCE LNL E+DYFGL D + WLD K + Q++G
Sbjct: 2 DDSDHQLQVKGNWKGILLQEKVCELLNLHEKDYFGLRFIDASGQTHWLDGNKSLSSQLKG 181
Query: 69 --VPWNFTFNVKFYPPDPAQLTEDITRYYLCLQLRQDIVAGRLPCSFATLALLGSYTIQS 126
P F VKFY DP +L E+ITRY LQ++QDI+ GRLP +F + L +Y +QS
Sbjct: 182 CQTPHKLYFGVKFYAADPCKLREEITRYLFFLQVKQDILQGRLPVTFDEASELCAYAVQS 361
Query: 127 ELGDYDPELHGVDYVSDFKLAPNQTKELEEKVMELHK 163
ELGD+DP H YVS+F PNQT+ELE +V LH+
Sbjct: 362 ELGDFDPRQHTDGYVSEFCFIPNQTEELERRVAGLHR 472
>28244
Length = 422
Score = 79.0 bits (193), Expect = 6e-15, Method: Composition-based stats.
Identities = 47/124 (37%), Positives = 67/124 (54%), Gaps = 4/124 (3%)
Frame = -1
Query: 212 LVYKDKLRINRFPWPKVLKISYKRSSF-FIKIRPGEQEQYESTIG-FKLPSYRAAKKLWK 269
LV++ +I F WPK+ ++ +K + + E Q + I F+L S +A K LWK
Sbjct: 422 LVFEGNXKIGLFFWPKMTRLDFKGKKLTLVAVEDDENGQSQDHIFVFRLQSEKACKHLWK 243
Query: 270 VCVEHHTFFRLTSTDTIPKSK--FLALGSKFRYSGRTQAQTRQASALIDRPAPHFERTAS 327
VEHH FFRL P ++ F +GS+FRYSGRT+ QT + R + FER S
Sbjct: 242 CAVEHHAFFRLKGPVQGPNARQNFFRMGSRFRYSGRTEYQTSTMNRA--RRSVKFERKPS 69
Query: 328 KRAS 331
+R S
Sbjct: 68 QRYS 57
>13951
Length = 720
Score = 50.4 bits (119), Expect(2) = 7e-15, Method: Compositional matrix adjust.
Identities = 26/64 (40%), Positives = 39/64 (60%), Gaps = 3/64 (4%)
Frame = -2
Query: 4 KVSLLDDTVYECVVEKHAKGQDLLKRVCEHLNLLEEDYFGLAIWDNATS---KTWLDSAK 60
+V LLD ++++A+G++L +VC+HL+L+E+DYFGL D S K WL K
Sbjct: 383 EVVLLDGEHVNFELDRNAEGRELFDKVCQHLDLIEKDYFGLQFVDERISNHLKCWLSPDK 204
Query: 61 EIKK 64
I K
Sbjct: 203 RISK 192
Score = 48.1 bits (113), Expect(2) = 7e-15, Method: Compositional matrix adjust.
Identities = 23/50 (46%), Positives = 31/50 (62%)
Frame = -1
Query: 60 KEIKKQVRGVPWNFTFNVKFYPPDPAQLTEDITRYYLCLQLRQDIVAGRL 109
K+ + + +G PW F F +KFYPPDP QL E +TR+ + L VAG L
Sbjct: 204 KDFQNRKKGGPWLFDFALKFYPPDPTQLRESLTRWLVVLH-----VAGEL 70
>08363
Length = 1878
Score = 63.2 bits (152), Expect = 3e-10, Method: Compositional matrix adjust.
Identities = 43/128 (33%), Positives = 62/128 (48%), Gaps = 30/128 (23%)
Frame = +1
Query: 487 PPLVKTQTVTISDNANAVKSEIPTKDVPIVHTETKTITYE-------------------- 526
PP V T++V + V +PTK+VP+V TET+T+TYE
Sbjct: 115 PPTVATESVHYQPDVEEVP--VPTKNVPLVKTETRTVTYEREGFPFDGEDGVLVSASSHS 288
Query: 527 ---------AAQTVKGGISETRIEKRIVITG-DADIDHDQVLVQAIKEAKEQHPDMSVTK 576
+T K G+ ETR+E R+V++ D D D+D L AI+ E +PDMSV +
Sbjct: 289 TRMQTIETTTYKTEKDGVQETRVEHRVVLSSTDDDFDYDAALADAIRSVTEFNPDMSVER 468
Query: 577 VVVHQETE 584
+ Q E
Sbjct: 469 IECVQXIE 492
>03469
Length = 1275
Score = 60.5 bits (145), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 39/111 (35%), Positives = 56/111 (50%), Gaps = 31/111 (27%)
Frame = -3
Query: 508 IPTKDVPIVHTETKTITYE-----------------------------AAQTVKGGISET 538
+PTK+VP+V TET+T+TYE +T K G+ ET
Sbjct: 1258 VPTKNVPLVKTETRTVTYEREGFPFDGEDGVLVSASSHSTRMQTIETTTYKTEKDGVQET 1079
Query: 539 RIEKRIVITG-DADIDHDQVLVQAIKEAKEQHPDMSVTKV-VVHQETEIAD 587
R+E R+V++ D D D+D L AI+ E +PDMSV ++ V Q E+ D
Sbjct: 1078 RVEHRVVLSSTDDDFDYDAALADAIRSVTEFNPDMSVERIECVQQIEEVKD 926
>05888
Length = 490
Score = 48.9 bits (115), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 22/36 (61%), Positives = 26/36 (72%)
Frame = -2
Query: 294 LGSKFRYSGRTQAQTRQASALIDRPAPHFERTASKR 329
LGSKFRYSGRT Q R +S +DRP P+FER+ R
Sbjct: 489 LGSKFRYSGRTLYQARHSSQTLDRPDPYFERSQPAR 382
>20292
Length = 1014
Score = 31.2 bits (69), Expect = 1.3, Method: Compositional matrix adjust.
Identities = 18/47 (38%), Positives = 23/47 (48%)
Frame = +3
Query: 6 SLLDDTVYECVVEKHAKGQDLLKRVCEHLNLLEEDYFGLAIWDNATS 52
SLL D YEC +E H Q +L E ++ L GL + N TS
Sbjct: 570 SLLQDVSYECCIEVHGPRQTIL----EAMSHLTSKDTGLTLAANGTS 698
>17496
Length = 461
Score = 30.8 bits (68), Expect = 1.7, Method: Compositional matrix adjust.
Identities = 15/38 (39%), Positives = 23/38 (60%), Gaps = 2/38 (5%)
Frame = +3
Query: 190 DLHKAKDLEGVDIILGVCSSGLL--VYKDKLRINRFPW 225
DLH+A+ +GV ++L SGL +K K +R+PW
Sbjct: 111 DLHRARTFQGVTLLLWETLSGLQKPGWKGKELKSRWPW 224
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000362906 | hsapiens_gene_ensembl | Protein 4.1
(Band 4.1) (P4.1) (EPB4.1) (4.1R).
[Source:Uniprot/SWISSPROT;Acc:P11171]
(588 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
00990 380 e-106
18811 186 2e-47
11374 175 4e-44
17332 146 2e-35
28244 79 6e-15
13951 50 7e-15
08363 63 3e-10
03469 60 2e-09
05888 49 6e-06
20292 31 1.3
17496 31 1.7
>00990
Length = 3161
Score = 380 bits (975), Expect = e-106, Method: Compositional matrix adjust.
Identities = 178/333 (53%), Positives = 244/333 (73%), Gaps = 5/333 (1%)
Frame = +3
Query: 4 KVSLLDDTVYECVVEKHAKGQDLLKRVCEHLNLLEEDYFGLAIWDNATS---KTWLDSAK 60
+V LLD ++++A+G++L +VC+HL+L+E+DYFGL D S K WL K
Sbjct: 267 EVVLLDGEHVNFELDRNAEGRELFDKVCQHLDLIEKDYFGLQFVDERISNHLKCWLSPDK 446
Query: 61 EIKKQVRGVPWNFTFNVKFYPPDPAQLTEDITRYYLCLQLRQDIVAGRLPCSFATLALLG 120
I KQ +G PW F F +KFYPPDP QL E +TR+ + LQ R+DI++G+LP ++ T A+LG
Sbjct: 447 RISKQKKGGPWLFDFALKFYPPDPTQLRESLTRWLVVLQTRRDILSGKLPATYLTQAMLG 626
Query: 121 SYTIQSELGDYDPELH-GVDYVSDFKLAPNQTKELEEKVMELHKSYRSMTPAQADLEFLE 179
SY +Q+++GDYDP H GV+Y+ D APNQT +L EK++ELH+ ++ TP +A+ FLE
Sbjct: 627 SYCVQADVGDYDPNEHRGVEYIRDTPFAPNQTIDLLEKIVELHRQHKGQTPDEAETNFLE 806
Query: 180 NAKKLSMYGVDLHKAKDLEGVDIILGVCSSGLLVYKDKLRINRFPWPKVLKISYKRSSFF 239
NAKKL+MYGVDLH A+D+ VDI+LGVC+SGL VY++KLRI+RF WPK+LKISYKR F+
Sbjct: 807 NAKKLAMYGVDLHAAQDVNNVDIMLGVCASGLQVYREKLRISRFVWPKILKISYKRRQFY 986
Query: 240 IKIRPGEQEQYESTIGFKLPSYRAAKKLWKVCVEHHTFFRLTSTD-TIPKSKFLALGSKF 298
IK+RP + E++ FKL ++R AK+LWK+CVEHH FFRL + + + F LGSKF
Sbjct: 987 IKVRPSDNSAMENSFCFKLATHRLAKRLWKICVEHHAFFRLREAEQSQNAAMFPRLGSKF 1166
Query: 299 RYSGRTQAQTRQASALIDRPAPHFERTASKRAS 331
RYSGRT QTRQ+S ++DRP P+FER+ R+S
Sbjct: 1167RYSGRTLYQTRQSSQILDRPNPYFERSQPARSS 1265
Score = 41.6 bits (96), Expect = 8e-04, Method: Compositional matrix adjust.
Identities = 21/55 (38%), Positives = 33/55 (60%), Gaps = 2/55 (3%)
Frame = +3
Query: 532 KGGISETRIEKRIVITG--DADIDHDQVLVQAIKEAKEQHPDMSVTKVVVHQETE 584
K GI TR+E ++V++ D + D+D L AI+ E +PDMSV ++ Q+ E
Sbjct: 2145 KDGIQHTRVEHKVVLSSADDEEFDYDAALADAIRSVTEFNPDMSVERIECVQQIE 2309
>18811
Length = 478
Score = 186 bits (473), Expect = 2e-47, Method: Compositional matrix adjust.
Identities = 79/134 (58%), Positives = 108/134 (80%)
Frame = -2
Query: 136 HGVDYVSDFKLAPNQTKELEEKVMELHKSYRSMTPAQADLEFLENAKKLSMYGVDLHKAK 195
HG DY+ D APNQ EL EK++ELH+ ++ TP +A++ +LENAKKLSMYGVDLH A+
Sbjct: 402 HGADYIKDIPFAPNQAPELLEKIVELHRQHKGQTPDEAEVNYLENAKKLSMYGVDLHAAQ 223
Query: 196 DLEGVDIILGVCSSGLLVYKDKLRINRFPWPKVLKISYKRSSFFIKIRPGEQEQYESTIG 255
D+ VDI+LGVCSSGL VY+DKLRI+RF WPK++KISYKR F++K+RP + + E+++
Sbjct: 222 DVNNVDIMLGVCSSGLQVYRDKLRISRFVWPKIIKISYKRKHFYVKVRPADNKGLETSVS 43
Query: 256 FKLPSYRAAKKLWK 269
F+LP++R AK+LWK
Sbjct: 42 FRLPTHRLAKRLWK 1
>11374
Length = 800
Score = 175 bits (444), Expect = 4e-44, Method: Compositional matrix adjust.
Identities = 80/140 (57%), Positives = 104/140 (74%), Gaps = 1/140 (0%)
Frame = +3
Query: 191 LHKAKDLEGVDIILGVCSSGLLVYKDKLRINRFPWPKVLKISYKRSSFFIKIRPGEQEQY 250
LH A+D+ VDI+LGVC+SGL VY++KLRI+RF WPK+LKISYKR F+IK+RP +
Sbjct: 3 LHAAQDVNNVDIMLGVCASGLQVYREKLRISRFVWPKILKISYKRRQFYIKVRPSDNSAM 182
Query: 251 ESTIGFKLPSYRAAKKLWKVCVEHHTFFRLTSTD-TIPKSKFLALGSKFRYSGRTQAQTR 309
E++ FKL ++R AK+LWK+CVEHH FFRL + + + F LGSKFRYSGRT QTR
Sbjct: 183 ENSFCFKLATHRLAKRLWKICVEHHAFFRLREAEQSQNAAMFPRLGSKFRYSGRTLYQTR 362
Query: 310 QASALIDRPAPHFERTASKR 329
+S +DRP P+FER+ R
Sbjct: 363 HSSQTLDRPDPYFERSQPAR 422
>17332
Length = 473
Score = 146 bits (369), Expect = 2e-35, Method: Composition-based stats.
Identities = 74/157 (47%), Positives = 100/157 (63%), Gaps = 2/157 (1%)
Frame = +2
Query: 9 DDTVYECVVEKHAKGQDLLKRVCEHLNLLEEDYFGLAIWDNATSKTWLDSAKEIKKQVRG 68
DD+ ++ V+ + KG L ++VCE LNL E+DYFGL D + WLD K + Q++G
Sbjct: 2 DDSDHQLQVKGNWKGILLQEKVCELLNLHEKDYFGLRFIDASGQTHWLDGNKSLSSQLKG 181
Query: 69 --VPWNFTFNVKFYPPDPAQLTEDITRYYLCLQLRQDIVAGRLPCSFATLALLGSYTIQS 126
P F VKFY DP +L E+ITRY LQ++QDI+ GRLP +F + L +Y +QS
Sbjct: 182 CQTPHKLYFGVKFYAADPCKLREEITRYLFFLQVKQDILQGRLPVTFDEASELCAYAVQS 361
Query: 127 ELGDYDPELHGVDYVSDFKLAPNQTKELEEKVMELHK 163
ELGD+DP H YVS+F PNQT+ELE +V LH+
Sbjct: 362 ELGDFDPRQHTDGYVSEFCFIPNQTEELERRVAGLHR 472
>28244
Length = 422
Score = 79.0 bits (193), Expect = 6e-15, Method: Composition-based stats.
Identities = 47/124 (37%), Positives = 67/124 (54%), Gaps = 4/124 (3%)
Frame = -1
Query: 212 LVYKDKLRINRFPWPKVLKISYKRSSF-FIKIRPGEQEQYESTIG-FKLPSYRAAKKLWK 269
LV++ +I F WPK+ ++ +K + + E Q + I F+L S +A K LWK
Sbjct: 422 LVFEGNXKIGLFFWPKMTRLDFKGKKLTLVAVEDDENGQSQDHIFVFRLQSEKACKHLWK 243
Query: 270 VCVEHHTFFRLTSTDTIPKSK--FLALGSKFRYSGRTQAQTRQASALIDRPAPHFERTAS 327
VEHH FFRL P ++ F +GS+FRYSGRT+ QT + R + FER S
Sbjct: 242 CAVEHHAFFRLKGPVQGPNARQNFFRMGSRFRYSGRTEYQTSTMNRA--RRSVKFERKPS 69
Query: 328 KRAS 331
+R S
Sbjct: 68 QRYS 57
>13951
Length = 720
Score = 50.4 bits (119), Expect(2) = 7e-15, Method: Compositional matrix adjust.
Identities = 26/64 (40%), Positives = 39/64 (60%), Gaps = 3/64 (4%)
Frame = -2
Query: 4 KVSLLDDTVYECVVEKHAKGQDLLKRVCEHLNLLEEDYFGLAIWDNATS---KTWLDSAK 60
+V LLD ++++A+G++L +VC+HL+L+E+DYFGL D S K WL K
Sbjct: 383 EVVLLDGEHVNFELDRNAEGRELFDKVCQHLDLIEKDYFGLQFVDERISNHLKCWLSPDK 204
Query: 61 EIKK 64
I K
Sbjct: 203 RISK 192
Score = 48.1 bits (113), Expect(2) = 7e-15, Method: Compositional matrix adjust.
Identities = 23/50 (46%), Positives = 31/50 (62%)
Frame = -1
Query: 60 KEIKKQVRGVPWNFTFNVKFYPPDPAQLTEDITRYYLCLQLRQDIVAGRL 109
K+ + + +G PW F F +KFYPPDP QL E +TR+ + L VAG L
Sbjct: 204 KDFQNRKKGGPWLFDFALKFYPPDPTQLRESLTRWLVVLH-----VAGEL 70
>08363
Length = 1878
Score = 63.2 bits (152), Expect = 3e-10, Method: Compositional matrix adjust.
Identities = 43/128 (33%), Positives = 62/128 (48%), Gaps = 30/128 (23%)
Frame = +1
Query: 487 PPLVKTQTVTISDNANAVKSEIPTKDVPIVHTETKTITYE-------------------- 526
PP V T++V + V +PTK+VP+V TET+T+TYE
Sbjct: 115 PPTVATESVHYQPDVEEVP--VPTKNVPLVKTETRTVTYEREGFPFDGEDGVLVSASSHS 288
Query: 527 ---------AAQTVKGGISETRIEKRIVITG-DADIDHDQVLVQAIKEAKEQHPDMSVTK 576
+T K G+ ETR+E R+V++ D D D+D L AI+ E +PDMSV +
Sbjct: 289 TRMQTIETTTYKTEKDGVQETRVEHRVVLSSTDDDFDYDAALADAIRSVTEFNPDMSVER 468
Query: 577 VVVHQETE 584
+ Q E
Sbjct: 469 IECVQXIE 492
>03469
Length = 1275
Score = 60.5 bits (145), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 39/111 (35%), Positives = 56/111 (50%), Gaps = 31/111 (27%)
Frame = -3
Query: 508 IPTKDVPIVHTETKTITYE-----------------------------AAQTVKGGISET 538
+PTK+VP+V TET+T+TYE +T K G+ ET
Sbjct: 1258 VPTKNVPLVKTETRTVTYEREGFPFDGEDGVLVSASSHSTRMQTIETTTYKTEKDGVQET 1079
Query: 539 RIEKRIVITG-DADIDHDQVLVQAIKEAKEQHPDMSVTKV-VVHQETEIAD 587
R+E R+V++ D D D+D L AI+ E +PDMSV ++ V Q E+ D
Sbjct: 1078 RVEHRVVLSSTDDDFDYDAALADAIRSVTEFNPDMSVERIECVQQIEEVKD 926
>05888
Length = 490
Score = 48.9 bits (115), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 22/36 (61%), Positives = 26/36 (72%)
Frame = -2
Query: 294 LGSKFRYSGRTQAQTRQASALIDRPAPHFERTASKR 329
LGSKFRYSGRT Q R +S +DRP P+FER+ R
Sbjct: 489 LGSKFRYSGRTLYQARHSSQTLDRPDPYFERSQPAR 382
>20292
Length = 1014
Score = 31.2 bits (69), Expect = 1.3, Method: Compositional matrix adjust.
Identities = 18/47 (38%), Positives = 23/47 (48%)
Frame = +3
Query: 6 SLLDDTVYECVVEKHAKGQDLLKRVCEHLNLLEEDYFGLAIWDNATS 52
SLL D YEC +E H Q +L E ++ L GL + N TS
Sbjct: 570 SLLQDVSYECCIEVHGPRQTIL----EAMSHLTSKDTGLTLAANGTS 698
>17496
Length = 461
Score = 30.8 bits (68), Expect = 1.7, Method: Compositional matrix adjust.
Identities = 15/38 (39%), Positives = 23/38 (60%), Gaps = 2/38 (5%)
Frame = +3
Query: 190 DLHKAKDLEGVDIILGVCSSGLL--VYKDKLRINRFPW 225
DLH+A+ +GV ++L SGL +K K +R+PW
Sbjct: 111 DLHRARTFQGVTLLLWETLSGLQKPGWKGKELKSRWPW 224
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000296446 | hsapiens_gene_ensembl | cAMP-dependent
protein kinase type II-alpha regulatory subunit.
[Source:Uniprot/SWISSPROT;Acc:P13861]
(382 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
08195 377 e-105
27710 121 6e-28
18204 74 1e-13
20517 35 0.048
17480 32 0.47
27148 29 3.5
27853 28 5.7
>08195
Length = 2165
Score = 377 bits (968), Expect = e-105, Method: Compositional matrix adjust.
Identities = 194/399 (48%), Positives = 253/399 (63%), Gaps = 24/399 (6%)
Frame = -3
Query: 6 IPPGLTELLQGYTVEVLRQQPPDLVEFAVEYFTRLR----EARAPASVLPAATPRQSLGH 61
IPPGLTELLQ +TV LR++P DLV+FA YF RLR +A P Q+ H
Sbjct: 2019 IPPGLTELLQEFTVAALRERPSDLVDFAASYFNRLRLLNGDAVDPKCFTGGVRFSQTGSH 1840
Query: 62 PPPEPGPDRVADAKGXXXXXXXXXXXXXXXXRFNRRVSVCAETYNPDEEEEDTDPRVIHP 121
G RF RR SV AE YNP+ +E+ + ++++P
Sbjct: 1839 ILAHNG---TFAQNNSDDDEAMLEPPPSNTARF-RRKSVSAEAYNPETDEDGGEAKIVNP 1672
Query: 122 KTDEQRCRLQEACKDILLFKNLDQEQLSQVLDAMFERIVKADEHVIDQGDDGDNFYVIER 181
K+D QR RL + K+ILLF++LD EQ+ +VLDAMFE+ V+ EH+IDQGDDGDNFYVI+
Sbjct: 1671 KSDIQRQRLADVVKNILLFRSLDPEQMQEVLDAMFEKSVQPGEHIIDQGDDGDNFYVIDS 1492
Query: 182 GTYDILVTKDNQTRSVGQYDNRGSFGELALMYNTPRAATIVATSEGSLWGLDRVTFRRII 241
GTYDI V + Q + VG YDN G FGELALMYN PRAATI+A+S G++W LDR TFRRI+
Sbjct: 1491 GTYDIYVDVEGQAKLVGNYDNSGFFGELALMYNMPRAATIIASSTGTIWALDRTTFRRIV 1312
Query: 242 VKNNAKKRKMFESFIESVPLLKSLEVSERMKIVDVIGEKIYKDGERIITQ---------- 291
+K +KRK +ES +ESVPLLKSL++ ERM + D + + Y+DG +II Q
Sbjct: 1311 LKTAFQKRKKYESLLESVPLLKSLDLYERMNVADALQTRTYEDGVQIIKQGDAADVMYFV 1132
Query: 292 ----------TKSNKDGGNQEVEIARCHKGQYFGELALVTNKPRAASAYAVGDVKCLVMD 341
K + D E ++ KG YFGELAL+T++PRAASAYA G VKC V+D
Sbjct: 1131 ESGQVRIAMTNKESTDPSAGETDVTVLEKGGYFGELALITHQPRAASAYAQGTVKCAVLD 952
Query: 342 VQAFERLLGPCMDIMKRNISHYEEQLVKMFGSSVDLGNL 380
V AFERL+GPCMD++KRNI Y+ Q+ +FG SV + ++
Sbjct: 951 VHAFERLMGPCMDVLKRNIDDYDSQISSIFGKSVSMKDM 835
>27710
Length = 429
Score = 121 bits (303), Expect = 6e-28, Method: Compositional matrix adjust.
Identities = 60/134 (44%), Positives = 87/134 (64%)
Frame = +2
Query: 164 EHVIDQGDDGDNFYVIERGTYDILVTKDNQTRSVGQYDNRGSFGELALMYNTPRAATIVA 223
E++I QGD+GDNFYVI+ G D+ V + T GSFGELAL+Y TPRAAT+ A
Sbjct: 2 ENIIQQGDEGDNFYVIDVGEVDVFVNSELVT----TISEGGSFGELALIYGTPRAATVRA 169
Query: 224 TSEGSLWGLDRVTFRRIIVKNNAKKRKMFESFIESVPLLKSLEVSERMKIVDVIGEKIYK 283
S+ LWG+DR ++RRI++ + +KRKM+E F+ V +L+SL+ ER+ + D + +
Sbjct: 170 KSDVKLWGIDRDSYRRILMGSTIRKRKMYEEFLSRVSILESLDKWERLTVADSLETCAFD 349
Query: 284 DGERIITQTKSNKD 297
DGE I+ Q + D
Sbjct: 350 DGETIVKQGAAGDD 391
Score = 39.7 bits (91), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 26/71 (36%), Positives = 37/71 (52%)
Frame = +2
Query: 300 NQEVEIARCHKGQYFGELALVTNKPRAASAYAVGDVKCLVMDVQAFERLLGPCMDIMKRN 359
N E+ + +G FGELAL+ PRAA+ A DVK +D ++ R+L M R
Sbjct: 77 NSEL-VTTISEGGSFGELALIYGTPRAATVRAKSDVKLWGIDRDSYRRIL---MGSTIRK 244
Query: 360 ISHYEEQLVKM 370
YEE L ++
Sbjct: 245 RKMYEEFLSRV 277
Score = 32.3 bits (72), Expect = 0.33, Method: Compositional matrix adjust.
Identities = 19/77 (24%), Positives = 38/77 (49%)
Frame = +2
Query: 111 EEDTDPRVIHPKTDEQRCRLQEACKDILLFKNLDQEQLSQVLDAMFERIVKADEHVIDQG 170
+ D+ R++ T +R +E + + ++LD+ + V D++ E ++ QG
Sbjct: 197 DRDSYRRILMGSTIRKRKMYEEFLSRVSILESLDKWERLTVADSLETCAFDDGETIVKQG 376
Query: 171 DDGDNFYVIERGTYDIL 187
GD+FY+I G +L
Sbjct: 377 AAGDDFYIILEGCAVVL 427
>18204
Length = 429
Score = 73.9 bits (180), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 48/146 (32%), Positives = 75/146 (51%), Gaps = 19/146 (13%)
Frame = -1
Query: 205 SFGELALMYNTPRAATIVATSEGSLWGLDRVTFRRIIVKNNAKKRKMFESFIESVPLLKS 264
+FGELA++YN R A++ A ++ +W LDR F+ I++K ++R+ F++SV +L+
Sbjct: 429 AFGELAILYNCTRTASVKAVTDVKVWVLDRQMFQAIMMKTGLQRREENIRFLKSVSVLRD 250
Query: 265 LEVSERMKIVDVIGEKIYKDGERII-------------------TQTKSNKDGGNQEVEI 305
L + KI DV+ + +GE II TQT + G + EI
Sbjct: 249 LPSDKLAKIADVLEIDFFHEGEFIIREGCTGDTFFLINKGEVRVTQTVA---GHEEPQEI 79
Query: 306 ARCHKGQYFGELALVTNKPRAASAYA 331
+ +G YFGE AL+ R AS A
Sbjct: 78 RKLKRGDYFGEKALLGEDRRTASCIA 1
Score = 39.3 bits (90), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 22/54 (40%), Positives = 30/54 (55%)
Frame = -1
Query: 314 FGELALVTNKPRAASAYAVGDVKCLVMDVQAFERLLGPCMDIMKRNISHYEEQL 367
FGELA++ N R AS AV DVK V+D Q F+ ++ MK + EE +
Sbjct: 426 FGELAILYNCTRTASVKAVTDVKVWVLDRQMFQAIM------MKTGLQRREENI 283
>20517
Length = 749
Score = 35.0 bits (79), Expect = 0.048, Method: Compositional matrix adjust.
Identities = 32/104 (30%), Positives = 50/104 (48%), Gaps = 9/104 (8%)
Frame = +3
Query: 175 NFYVIERGTYDILVTK----DNQTRSVGQYDNRGSFGELALMYNTPRAATIVATSEGSLW 230
+FY I GT ++VT+ + TR++ D SFGELA++ + R AT+ +E L
Sbjct: 18 SFYFILSGT--VVVTQFERQYSTTRTLVTLDQGMSFGELAVITGSRRQATVSTMTEVELL 191
Query: 231 GLDRVTFRRIIVKNNAKKRKMF-----ESFIESVPLLKSLEVSE 269
+ F I + A RK+ F+ SV LK+ V +
Sbjct: 192 CISAKDFEDIFM---AGGRKIITDPDHNKFLRSVDFLKAWPVQQ 314
>17480
Length = 649
Score = 32.0 bits (71), Expect = 0.47, Method: Compositional matrix adjust.
Identities = 17/60 (28%), Positives = 35/60 (58%)
Frame = +3
Query: 256 IESVPLLKSLEVSERMKIVDVIGEKIYKDGERIITQTKSNKDGGNQEVEIARCHKGQYFG 315
++SV +++++ V + M+IVD + +K Y D E + + K N + ++ +GQY+G
Sbjct: 234 LQSVLMVRNVPVEKAMEIVDSVFDKCYNDLEPVGRRPKKNSRDPERALQ-----EGQYYG 398
>27148
Length = 718
Score = 28.9 bits (63), Expect = 3.5, Method: Compositional matrix adjust.
Identities = 14/25 (56%), Positives = 19/25 (76%), Gaps = 1/25 (4%)
Frame = -3
Query: 200 YDNRG-SFGELALMYNTPRAATIVA 223
Y NRG SFGELA+M T R +T+++
Sbjct: 293 YYNRGDSFGELAIMNATRRQSTVIS 219
>27853
Length = 864
Score = 28.1 bits (61), Expect = 5.7, Method: Compositional matrix adjust.
Identities = 18/71 (25%), Positives = 37/71 (52%), Gaps = 1/71 (1%)
Frame = +2
Query: 154 AMFERIVKADEHVIDQGDDGDNFYVIERGTYDILVT-KDNQTRSVGQYDNRGSFGELALM 212
A+ ++ +A + + QGD+ D+ Y++ G ++T + VG+Y G + ++
Sbjct: 215 ALDWQMTEAGKALFRQGDNSDSVYIVLTGRLRSVITLLGGKKEVVGEYGRGELVGIVEVL 394
Query: 213 YNTPRAATIVA 223
+T RA T +A
Sbjct: 395 THTERATTNMA 427
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000247207 | hsapiens_gene_ensembl | Heat
shock-related 70 kDa protein 2 (Heat shock 70 kDa protein 2).
[Source:Uniprot/SWISSPROT;Acc:P54652]
(639 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
30255 280 e-104
21024 218 9e-57
27378 194 1e-49
26390 165 6e-41
37715 149 4e-36
24750 139 3e-33
06909 99 1e-24
31218 94 1e-19
09881 88 1e-17
20979 86 3e-17
12271 64 2e-10
13684 55 7e-08
03996 52 7e-07
34036 50 3e-06
13300 49 5e-06
>30255
Length = 1761
Score = 280 bits (717), Expect(2) = e-104, Method: Compositional matrix adjust.
Identities = 144/206 (69%), Positives = 156/206 (75%)
Frame = -1
Query: 331 KGQIQEIVLVGGSTRIPKIQKLLQDFFNGKELNKSINPDEXXXXXXXXXXXILIGDKSEN 390
K I EIVLVGGSTRIPKIQKLLQDFFNGKEL KSINPDE IL GDKSE
Sbjct: 1644 KPGIHEIVLVGGSTRIPKIQKLLQDFFNGKELCKSINPDEAVAYGACVQAAILHGDKSEE 1465
Query: 391 VQDXXXXXXXXXXXGIETAGGVMTPLIKRNXXXXXXXXXXXXXYSDNQSSVLVQVYEGER 450
VQD GIETAGGVMT LIKRN YSDNQ VL+QVYEGER
Sbjct: 1464 VQDLLLLDVAPLSMGIETAGGVMTALIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGER 1285
Query: 451 AMTKDNNLLGKFDLTGIPPAPRGVPQIEVTFDIDANGILNVTAADKSTGKENKITITNDK 510
AMT+DNNLLGKF+LTGIPPAPRGVPQIEVTFDIDANGILNV+AADKSTGKENKITITNDK
Sbjct: 1284 AMTRDNNLLGKFELTGIPPAPRGVPQIEVTFDIDANGILNVSAADKSTGKENKITITNDK 1105
Query: 511 GRLSKDDIDRMVQEAERYKSEDEANR 536
GRLSK++I+RMV +AE+ ++ + R
Sbjct: 1104 GRLSKEEIERMVNDAEKSRTMMTSRR 1027
Score = 117 bits (293), Expect(2) = e-104, Method: Compositional matrix adjust.
Identities = 52/79 (65%), Positives = 69/79 (87%)
Frame = -3
Query: 537 DRVAAKNALESYTYNIKQTVEDEKLRGKISEQDKNKILDKCQEVINWLDRNQMAEKDEYE 596
+R+++KN+LESY +++K T+EDEK++ KI E+DK I+DKC EVI+WLD NQ AEKDEY+
Sbjct: 1027 NRISSKNSLESYAFHMKSTIEDEKIKDKIGEEDKKTIVDKCNEVISWLDANQTAEKDEYD 848
Query: 597 HKQKELERVCNPIISKLYQ 615
KQKELE+VCNPII+KLYQ
Sbjct: 847 DKQKELEKVCNPIITKLYQ 791
>21024
Length = 3220
Score = 218 bits (554), Expect = 9e-57, Method: Compositional matrix adjust.
Identities = 127/331 (38%), Positives = 189/331 (57%), Gaps = 10/331 (3%)
Frame = +1
Query: 264 RRLRTAC------ERAKRTLSSSTQASIEIDSLYEGVD----FYTSITRARFEELNADLF 313
+R++ C +++K LSSS Q I + L ++R++FE L L
Sbjct: 988 QRIQWLCRDYVRQQKSKIELSSSLQTDINLPYLTMDASGPKHMNLKLSRSKFESLVESLV 1167
Query: 314 RGTLEPVEKALRDAKLDKGQIQEIVLVGGSTRIPKIQKLLQDFFNGKELNKSINPDEXXX 373
+ T+ P +KAL+DA++ K I E++LVGG +R+PK+Q +QD F G+ +KS+NPDE
Sbjct: 1168 KRTVGPCQKALQDAEVKKSDIGEVILVGGMSRMPKVQSTVQDLF-GRTPSKSVNPDEAVA 1344
Query: 374 XXXXXXXXILIGDKSENVQDXXXXXXXXXXXGIETAGGVMTPLIKRNXXXXXXXXXXXXX 433
+L GD V D GIET GGV T LI RN
Sbjct: 1345 IGAAIQGGVLAGD----VTDVLLLDVTPLSLGIETLGGVFTKLINRNTTIPTKKSQVFST 1512
Query: 434 YSDNQSSVLVQVYEGERAMTKDNNLLGKFDLTGIPPAPRGVPQIEVTFDIDANGILNVTA 493
+D Q+ V ++V++GER M DN LLG+F L GIPPAPRGVPQ+EVTFDIDANGI+NV+A
Sbjct: 1513 AADGQTQVEIKVHQGEREMANDNKLLGQFTLVGIPPAPRGVPQVEVTFDIDANGIVNVSA 1692
Query: 494 ADKSTGKENKITITNDKGRLSKDDIDRMVQEAERYKSEDEANRDRVAAKNALESYTYNIK 553
DK TGKE +I I + G LSKD+I+ M++ AE + +D ++ V N +S ++ +
Sbjct: 1693 RDKGTGKEQQIVIQSSGG-LSKDEIENMIKNAEAHAEDDRRKKELVEVLNQADSIIHDTE 1869
Query: 554 QTVEDEKLRGKISEQDKNKILDKCQEVINWL 584
+E+ + ++ +++ +K+ +K EV L
Sbjct: 1870 SKMEE--FKDQLPQEECDKLREKINEVKQLL 1956
Score = 184 bits (467), Expect = 1e-46, Method: Compositional matrix adjust.
Identities = 117/271 (43%), Positives = 163/271 (60%), Gaps = 2/271 (0%)
Frame = +3
Query: 4 RGPAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQVAM 62
+G IGIDLGTT SCV + + + +++ N +G+RTTPS +AFT D ER+ G AK Q
Sbjct: 243 KGHVIGIDLGTTNSCVALMEGKQAKVLENSEGSRTTPSVIAFTKDGERISGMPAKRQAVT 422
Query: 63 NPTNTIFDAKRLIGRKFEDATVQSDMKHWPFRVVSEGGKPKVQVEYKGETKTFFPEEISS 122
N NT+ KRLIGR+FED VQ DMK+ +++V + VE +G K + P ++ +
Sbjct: 423 NAENTLSATKRLIGRRFEDPEVQKDMKNVSYKIV-KASNGDAWVEAQG--KMYSPSQVGA 593
Query: 123 MVLTKMKEIAEAYLGGKVHSAVITVPAYFNDSQRQATKDAGTITGLNVLRIINEPTAAAI 182
VL KMKE AE+YLG KV++AV+TVPAYFNDSQRQATKDAG I+GL + ++ T +
Sbjct: 594 FVLMKMKETAESYLGSKVNNAVVTVPAYFNDSQRQATKDAGQISGLKCV-ACDQRTHSCS 770
Query: 183 AYGLDKKGCAGGEKNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGE-DFDNRMV 241
+ + LI G T +S + + + + T +TH E FDN MV
Sbjct: 771 SCFMAWTSLKIK**RCLI*AEGRLT-SLSWRSRRECLKSNQPT--ETHSWEERTFDNYMV 941
Query: 242 SHLAEEFKRKHKKDIGPNKRAVRRLRTACER 272
+ LA EFK++ DI + AV+RLR A E+
Sbjct: 942 NFLASEFKKEQGLDITKDPMAVQRLREAAEK 1034
>27378
Length = 410
Score = 194 bits (492), Expect = 1e-49, Method: Compositional matrix adjust.
Identities = 94/124 (75%), Positives = 106/124 (85%)
Frame = -1
Query: 247 EFKRKHKKDIGPNKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGVDFYTSITRARFE 306
EFKRK+KKD+ N RA+RRLRTA ERAKRTLSSST+A+IE+D+L+EG DFYT I+RARFE
Sbjct: 410 EFKRKYKKDLRSNPRALRRLRTAAERAKRTLSSSTEATIEVDALFEGHDFYTKISRARFE 231
Query: 307 ELNADLFRGTLEPVEKALRDAKLDKGQIQEIVLVGGSTRIPKIQKLLQDFFNGKELNKSI 366
EL ADLFR TL PVEKAL DAK+DK I +IVLVGGSTRIPK+Q LLQ FF GK LN SI
Sbjct: 230 ELCADLFRQTLAPVEKALNDAKMDKQMIHDIVLVGGSTRIPKVQNLLQQFFGGKSLNLSI 51
Query: 367 NPDE 370
NPDE
Sbjct: 50 NPDE 39
>26390
Length = 665
Score = 165 bits (417), Expect = 6e-41, Method: Compositional matrix adjust.
Identities = 87/183 (47%), Positives = 112/183 (61%), Gaps = 6/183 (3%)
Frame = +2
Query: 405 GIETAGGVMTPLIKRNXXXXXXXXXXXXXYSDNQSSVLVQVYEGERAMTKDNNLLGKFDL 464
GIET GGVMT LI R DNQ SV +QVYEGER+ TKDN+LLG+FDL
Sbjct: 50 GIETVGGVMTTLIARGTTIPARKAKVFSTAQDNQDSVTIQVYEGERSRTKDNHLLGRFDL 229
Query: 465 TGIPPAPRGVPQIEVTFDIDANGILNVTAADKSTGKENKITITNDKGRLSKDDIDRMVQE 524
TGIP APRGVPQIEVTF +DANG++ V+A DK TG++N I I LS +D++RMVQE
Sbjct: 230 TGIPAAPRGVPQIEVTFQVDANGVMQVSAEDKGTGQKNDIIIQQSGSGLSPEDVERMVQE 409
Query: 525 AERYKSEDEANRDRVAAKNALESYTYNIKQTVED------EKLRGKISEQDKNKILDKCQ 578
A+ + ED R+ ++ LES Y + ++D + G +S+ D L Q
Sbjct: 410 AQDFAEEDRKFRELTESRTGLESLAYTAQHQLQDLHKMXASERPGTLSDDD----LHXAQ 577
Query: 579 EVI 581
EV+
Sbjct: 578 EVV 586
>37715
Length = 468
Score = 149 bits (376), Expect = 4e-36, Method: Compositional matrix adjust.
Identities = 72/113 (63%), Positives = 86/113 (76%)
Frame = -2
Query: 93 FRVVSEGGKPKVQVEYKGETKTFFPEEISSMVLTKMKEIAEAYLGGKVHSAVITVPAYFN 152
+V+++ KP +Q G TKTF PEEIS+MVL KM++IAEAYLG K+ +AV+TVPAYFN
Sbjct: 458 LKVINKSNKPHIQALVSGATKTFAPEEISAMVLGKMRDIAEAYLGKKIDNAVVTVPAYFN 279
Query: 153 DSQRQATKDAGTITGLNVLRIINEPTAAAIAYGLDKKGCAGGEKNVLIFDLGG 205
D+QRQATKDAGTI GLNV+RIINEPTAAAIAYGLDK+ GEK
Sbjct: 278 DAQRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKR---DGEKTFWCLTWAA 129
Score = 81.3 bits (199), Expect = 1e-15, Method: Composition-based stats.
Identities = 34/49 (69%), Positives = 44/49 (89%)
Frame = -1
Query: 196 KNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVSHL 244
+N+L+FDLGGGTFDVS+LTI++G+FEV +T GDTHLGGEDFD R++ H
Sbjct: 159 ENILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMDHF 13
>24750
Length = 552
Score = 139 bits (351), Expect = 3e-33, Method: Compositional matrix adjust.
Identities = 65/71 (91%), Positives = 71/71 (100%)
Frame = +1
Query: 442 LVQVYEGERAMTKDNNLLGKFDLTGIPPAPRGVPQIEVTFDIDANGILNVTAADKSTGKE 501
++QVYEGERAMT+DNNLLGKF+LTGIPPAPRGVPQIEVTFDIDANGILNV+AADKSTGKE
Sbjct: 154 MLQVYEGERAMTRDNNLLGKFELTGIPPAPRGVPQIEVTFDIDANGILNVSAADKSTGKE 333
Query: 502 NKITITNDKGR 512
NKITITNDKG+
Sbjct: 334 NKITITNDKGQ 366
>06909
Length = 456
Score = 99.4 bits (246), Expect(2) = 1e-24, Method: Compositional matrix adjust.
Identities = 45/65 (69%), Positives = 56/65 (86%)
Frame = -3
Query: 551 NIKQTVEDEKLRGKISEQDKNKILDKCQEVINWLDRNQMAEKDEYEHKQKELERVCNPII 610
++K T+EDEK++ KIS +DK ILDKC EVI WLD NQ+AEKDEY+ KQKE+E+VCNPII
Sbjct: 385 HMKSTIEDEKIKDKISTEDKKTILDKCDEVIAWLDANQLAEKDEYDDKQKEIEKVCNPII 206
Query: 611 SKLYQ 615
+KLYQ
Sbjct: 205 TKLYQ 191
Score = 32.7 bits (73), Expect(2) = 1e-24, Method: Composition-based stats.
Identities = 12/22 (54%), Positives = 18/22 (81%)
Frame = -1
Query: 527 RYKSEDEANRDRVAAKNALESY 548
+YK +DE + R++AKN+LESY
Sbjct: 456 KYKEDDEKQKSRISAKNSLESY 391
>31218
Length = 322
Score = 94.4 bits (233), Expect = 1e-19, Method: Compositional matrix adjust.
Identities = 48/100 (48%), Positives = 68/100 (68%)
Frame = +2
Query: 228 DTHLGGEDFDNRMVSHLAEEFKRKHKKDIGPNKRAVRRLRTACERAKRTLSSSTQASIEI 287
DTHLGGEDFD R+V +L + K+K +D+ + RA+ RLR + E+AKR LSS +++
Sbjct: 2 DTHLGGEDFDQRLVDYLVKLIKQKTGRDVRHDTRAMSRLRRSAEKAKRALSSQHSTKVDL 181
Query: 288 DSLYEGVDFYTSITRARFEELNADLFRGTLEPVEKALRDA 327
D + + T +TRA+FEELN DLFR TL V++AL D+
Sbjct: 182 DGVTSDLADLT-LTRAKFEELNTDLFRSTLTTVKRALEDS 298
>09881
Length = 600
Score = 87.8 bits (216), Expect = 1e-17, Method: Composition-based stats.
Identities = 41/106 (38%), Positives = 64/106 (60%)
Frame = +3
Query: 7 AIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTN 66
A G+ LGT +C+ V++ GK + AND G+R+TP VAFT + +G +AK + N N
Sbjct: 186 AYGVHLGTCSACLAVYKDGKTSVAANDAGDRSTPCVVAFTACDAEVGASAKQGIVSNVKN 365
Query: 67 TIFDAKRLIGRKFEDATVQSDMKHWPFRVVSEGGKPKVQVEYKGET 112
T+ + KR++G FED Q + P +VV++ +P +VE+K T
Sbjct: 366 TVCNVKRILGLTFEDPVTQEYLASSPVKVVNQKNQPMFEVEFKERT 503
Score = 45.8 bits (107), Expect = 5e-05, Method: Composition-based stats.
Identities = 24/50 (48%), Positives = 32/50 (64%)
Frame = +2
Query: 137 GGKVHSAVITVPAYFNDSQRQATKDAGTITGLNVLRIINEPTAAAIAYGL 186
G + AV+ VP+ F+D QR A A + G VLR+INE +AAA+AY L
Sbjct: 2 GKGIQDAVLAVPSDFSDKQRAAASAAASKAGFKVLRLINECSAAALAYDL 151
>20979
Length = 976
Score = 86.3 bits (212), Expect = 3e-17, Method: Compositional matrix adjust.
Identities = 48/140 (34%), Positives = 81/140 (57%), Gaps = 2/140 (1%)
Frame = +1
Query: 233 GEDFDNRMVSHLAEEF--KRKHKKDIGPNKRAVRRLRTACERAKRTLSSSTQASIEIDSL 290
G + R+ HLA+ F ++K + N RA+ +L ER K+ LS+++ +++ L
Sbjct: 70 GVEMTLRLRDHLAKVFNGQKKRSFKLEDNPRAMAKLLKEAERVKKVLSANSDHKAQVEGL 249
Query: 291 YEGVDFYTSITRARFEELNADLFRGTLEPVEKALRDAKLDKGQIQEIVLVGGSTRIPKIQ 350
EG DF ++R + EL DL +P+E AL+ +++ +I EI+L+GG +R+P++Q
Sbjct: 250 VEGEDFAAKVSREDYLELIKDLLARVTKPMEDALKVSEITMPEITEIILMGGGSRVPRVQ 429
Query: 351 KLLQDFFNGKELNKSINPDE 370
+ L F +L KSIN DE
Sbjct: 430 EELLKFSGKSDLGKSINTDE 489
>12271
Length = 1762
Score = 63.9 bits (154), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 30/76 (39%), Positives = 47/76 (61%)
Frame = +2
Query: 295 DFYTSITRARFEELNADLFRGTLEPVEKALRDAKLDKGQIQEIVLVGGSTRIPKIQKLLQ 354
DF +TR ++ L DL PV++ L +++ +I EI+L+GG +R+PKI ++L
Sbjct: 41 DFSCKVTRDKYLHLIQDLLDRVTLPVQQVLTASQITWAEITEIILMGGGSRLPKIHEILL 220
Query: 355 DFFNGKELNKSINPDE 370
D+ KEL KS+N DE
Sbjct: 221 DYSGKKELGKSLNTDE 268
Score = 32.7 bits (73), Expect = 0.43, Method: Compositional matrix adjust.
Identities = 23/98 (23%), Positives = 44/98 (44%), Gaps = 3/98 (3%)
Frame = +1
Query: 490 NVTAADKSTGKENKITIT---NDKGRLSKDDIDRMVQEAERYKSEDEANRDRVAAKNALE 546
N AA G K+ +T D LSKD + + + ++ DE A+N +E
Sbjct: 937 NKKAASAGKGFNEKLKVTVKVKDMAELSKDQVKQSKKRLTDWRKRDEEKAAVQKARNEVE 1116
Query: 547 SYTYNIKQTVEDEKLRGKISEQDKNKILDKCQEVINWL 584
S+ + + +E +++++ ILD+ + +WL
Sbjct: 1117 SFIITAQDKMSEETYLASSTDEERAXILDQLSQASDWL 1230
>13684
Length = 438
Score = 55.5 bits (132), Expect = 7e-08, Method: Composition-based stats.
Identities = 24/57 (42%), Positives = 36/57 (63%)
Frame = -3
Query: 7 AIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMN 63
A G+ LGT +C+ V++ GK + AND G+R+TP VAFT + +G +AK + N
Sbjct: 172 AYGVHLGTCSACLAVYKDGKTSVAANDAGDRSTPCVVAFTACDAEVGASAKQGIVSN 2
>03996
Length = 1105
Score = 52.0 bits (123), Expect = 7e-07, Method: Compositional matrix adjust.
Identities = 26/64 (40%), Positives = 41/64 (64%)
Frame = -2
Query: 307 ELNADLFRGTLEPVEKALRDAKLDKGQIQEIVLVGGSTRIPKIQKLLQDFFNGKELNKSI 366
EL DL +P+E AL+ +++ +I EI+L+GG +R+P++Q+ L F +L KSI
Sbjct: 1056 ELIKDLLARVTKPMEDALKVSEITMPEITEIILMGGGSRVPRVQEELLKFSGKSDLGKSI 877
Query: 367 NPDE 370
N DE
Sbjct: 876 NTDE 865
>34036
Length = 363
Score = 50.1 bits (118), Expect = 3e-06, Method: Composition-based stats.
Identities = 20/25 (80%), Positives = 24/25 (96%)
Frame = +2
Query: 591 EKDEYEHKQKELERVCNPIISKLYQ 615
EKDEY+ KQKE+E+VCNPII+KLYQ
Sbjct: 2 EKDEYDDKQKEIEKVCNPIITKLYQ 76
>13300
Length = 453
Score = 49.3 bits (116), Expect = 5e-06, Method: Compositional matrix adjust.
Identities = 35/149 (23%), Positives = 73/149 (48%), Gaps = 15/149 (10%)
Frame = +3
Query: 155 QRQATKDAGTITGLNVLRIINEPTAAAIAYGL-DKKGCAGGEKNVLIFDLGGGTFDVSIL 213
+R+A A G+NVL+++ + A A+ YG+ +K + + +D+G + +++
Sbjct: 3 ERRAIMTAADXVGINVLQLMTDSAAVALNYGVFRRKNFNTTAQYYMFYDMGATSTVATVV 182
Query: 214 T-----IEDGI-------FEVKSTAGDTHLGGEDFDNRMVSHLAEEFKRKHKKD--IGPN 259
+ +++G +K D LGG + R+ HLA+ F + K+ + N
Sbjct: 183 SYQVVKVKEGTRVESNPQLTIKGVGFDRTLGGLEMTLRLRDHLAKVFNGQKKRSFKLEDN 362
Query: 260 KRAVRRLRTACERAKRTLSSSTQASIEID 288
RA+ +L ER K+ LS+++ +++
Sbjct: 363 PRAMAKLLKEAERVKKVLSANSDHKAQVE 449
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000254675 | hsapiens_gene_ensembl | GTP-binding
nuclear protein Ran (GTPase Ran) (Ras-like protein TC4) (Androgen
receptor-associated protein 24). [Source:Uniprot/SWISSPROT;Acc:P62826]
(216 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
01972 339 e-104
34359 224 5e-91
08428 92 1e-19
14456 89 1e-18
05468 89 2e-18
17511 87 6e-18
33374 72 1e-17
34468 85 2e-17
13901 83 7e-17
07465 79 1e-15
11728 79 1e-15
26083 79 2e-15
11257 73 1e-13
19006 72 1e-13
07580 62 1e-12
30760 66 9e-12
33794 64 6e-11
13745 64 6e-11
12339 62 2e-10
19656 59 2e-09
33380 58 4e-09
35581 55 3e-08
01398 52 1e-07
32723 52 1e-07
26536 52 2e-07
13750 52 2e-07
31291 52 3e-07
27191 51 4e-07
00858 50 5e-07
19046 50 9e-07
29380 47 5e-06
24619 47 6e-06
00552 42 2e-04
36482 41 3e-04
08153 39 0.001
14775 38 0.003
09204 37 0.005
09827 37 0.008
33605 35 0.019
10708 35 0.019
20290 33 0.10
10862 32 0.16
13795 30 0.97
18248 29 1.5
33029 29 1.7
11357 27 4.6
02253 27 6.0
>01972
Length = 2359
Score = 339 bits (869), Expect(2) = e-104, Method: Compositional matrix adjust.
Identities = 157/180 (87%), Positives = 169/180 (93%)
Frame = +3
Query: 37 KKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRV 96
KKYVATLGVEVHPL+FHT+RG +KFNVWDTAGQEKFGGLRDGYYIQ QCA+IMFDVTSRV
Sbjct: 381 KKYVATLGVEVHPLLFHTSRGKLKFNVWDTAGQEKFGGLRDGYYIQGQCAVIMFDVTSRV 560
Query: 97 TYKNVPNWHRDLVRVCENIPIVLCGNKVDIKDRKVKAKSIVFHRKKNLQYYDISAKSNYN 156
TYKNVPNWHRDLVRVCENIPIVLCGNKVDIKDRKVKAK+IVFHRKKNLQYYDISAKSNYN
Sbjct: 561 TYKNVPNWHRDLVRVCENIPIVLCGNKVDIKDRKVKAKAIVFHRKKNLQYYDISAKSNYN 740
Query: 157 FEKPFLWLARKLIGDPNLEFVAMPALAPPEVVMDPALAAQYEHDLEVAQTTALPDEDDDL 216
FEKPFLWLARKL+GDPNLEFV MPAL PPEV MD LA +YE +L+VAQ ALPD+D+D+
Sbjct: 741 FEKPFLWLARKLVGDPNLEFVEMPALLPPEVAMDAVLAKKYEEELKVAQEVALPDDDEDI 920
Score = 55.5 bits (132), Expect(2) = e-104, Method: Compositional matrix adjust.
Identities = 26/32 (81%), Positives = 28/32 (87%)
Frame = +1
Query: 6 EPQVQFKLVLVGDGGTGKTTFVKRHLTGEFEK 37
E + FKLVLVGDGG GKTTFVKRH+TGEFEK
Sbjct: 289 EQEPTFKLVLVGDGGVGKTTFVKRHVTGEFEK 384
>34359
Length = 1042
Score = 224 bits (572), Expect(2) = 5e-91, Method: Compositional matrix adjust.
Identities = 109/136 (80%), Positives = 116/136 (85%)
Frame = +3
Query: 10 QFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQ 69
FKLVLVG VKRH+TG KKYVATLGVEVHPL F+T+RG ++FNVWDTAGQ
Sbjct: 51 NFKLVLVGGRWEWANNIVKRHVTGS*-KKYVATLGVEVHPLQFNTSRGLLRFNVWDTAGQ 227
Query: 70 EKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLCGNKVDIKDR 129
EKFGGLRDGYYIQ CAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLCGNKVDIKDR
Sbjct: 228 EKFGGLRDGYYIQGTCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLCGNKVDIKDR 407
Query: 130 KVKAKSIVFHRKKNLQ 145
KVKAK+IVFHRK+
Sbjct: 408 KVKAKAIVFHRKRTCS 455
Score = 127 bits (318), Expect(2) = 5e-91, Method: Compositional matrix adjust.
Identities = 58/79 (73%), Positives = 68/79 (86%)
Frame = +2
Query: 138 FHRKKNLQYYDISAKSNYNFEKPFLWLARKLIGDPNLEFVAMPALAPPEVVMDPALAAQY 197
++KNLQYYDISAKSNYNFEKPFLWLARKL+GDPNL FV MPAL PPEV MDP +A +Y
Sbjct: 431 LSQEKNLQYYDISAKSNYNFEKPFLWLARKLVGDPNLXFVEMPALLPPEVAMDPNMAKRY 610
Query: 198 EHDLEVAQTTALPDEDDDL 216
E +L+VAQ ALPD+D+D+
Sbjct: 611 EDELKVAQEVALPDDDEDI 667
>08428
Length = 1109
Score = 92.4 bits (228), Expect = 1e-19, Method: Compositional matrix adjust.
Identities = 53/160 (33%), Positives = 87/160 (54%), Gaps = 3/160 (1%)
Frame = -3
Query: 12 KLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQEK 71
K+ L+GD G GK++ V R +TG + +T+G + +F +WDTAGQEK
Sbjct: 1065 KVCLLGDSGVGKSSIVLRFVTGSYRPSQESTIGASFMSKSLVVDGAGYRFQIWDTAGQEK 886
Query: 72 FGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVC-ENIPIVLCGNKVDIKDRK 130
F L YY A A+I++DVT T+K+V +W ++L NI + + GNK D+++ +
Sbjct: 885 FRALAPMYYRGAAAAVIVYDVTRPRTFKSVKSWIQELRSFGPPNIVLAIAGNKCDLEELR 706
Query: 131 --VKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKL 168
V+ + + + + + SA + N E+ F LAR+L
Sbjct: 705 EVVEKDAQEYASSISAIFGETSAMTAVNVEEMFTELARQL 586
>14456
Length = 1867
Score = 89.4 bits (220), Expect = 1e-18, Method: Compositional matrix adjust.
Identities = 49/158 (31%), Positives = 83/158 (52%), Gaps = 8/158 (5%)
Frame = -1
Query: 19 GGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQEKFGGLRDG 78
GG GK++ + R ++ +F+ + T+GVE + +WDTAGQE+F LR
Sbjct: 1114 GGVGKSSLMNRFVSNKFDAQSFHTIGVEFLNKDVVVDDETYTMQIWDTAGQERFKSLRTP 935
Query: 79 YYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCE-----NIPIVLCGNKVDIKDRKV-- 131
+Y A C ++ F V S +++N+ W ++ + + P V+ GNK+D++ R+V
Sbjct: 934 FYRGADCCLLTFSVDSMQSFRNLSMWRKEFLYYADIQDGVTFPFVVLGNKIDVEGRQVTN 755
Query: 132 -KAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKL 168
+A+S N Y++ SAK N EK FL ++L
Sbjct: 754 EEARSWC-TANSNAPYFETSAKDATNVEKAFLAAVQRL 644
>05468
Length = 1558
Score = 89.0 bits (219), Expect = 2e-18, Method: Compositional matrix adjust.
Identities = 57/169 (33%), Positives = 96/169 (56%), Gaps = 10/169 (5%)
Frame = -3
Query: 11 FKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGP-IKFNVWDTAGQ 69
+K++++G+ GTGKT+ +KR++ F + Y AT+GV+ V + + I+ +WD AGQ
Sbjct: 1538 YKILVIGELGTGKTSIIKRYVHQFFSQHYRATIGVDFALKVLNWDADTLIRLQLWDIAGQ 1359
Query: 70 EKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDL---VRVCEN--IPIVLCGNKV 124
E+FG + YY +A A ++FDVT T+ V W DL V++ + +P VL NK
Sbjct: 1358 ERFGNMTRVYYKEAVGAFVVFDVTRASTFDAVTKWKNDLDSKVQLADGSPVPCVLLANKC 1179
Query: 125 D-IKDRKVKAKSIV--FHRKKN-LQYYDISAKSNYNFEKPFLWLARKLI 169
D K+ V S + F +K + +Y+ SAK N N ++ +L +++
Sbjct: 1178 DQAKEGLVNNTSQMDEFCSEKGFIGWYETSAKENINIDEAARFLVTRIL 1032
>17511
Length = 483
Score = 86.7 bits (213), Expect = 6e-18, Method: Compositional matrix adjust.
Identities = 40/124 (32%), Positives = 72/124 (58%), Gaps = 5/124 (4%)
Frame = -3
Query: 8 QVQFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTA 67
+V K++++GD G GKT+ + +++ +F +Y AT+G + + + +WDTA
Sbjct: 373 KVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTA 194
Query: 68 GQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLV-----RVCENIPIVLCGN 122
GQE+F L +Y A C +++FDVT T++++ +W + + R EN P V+ GN
Sbjct: 193 GQERFQSLGVAFYRGADCCVLVFDVTMPNTFRSLDSWRDEFLIQASPRDPENFPFVVIGN 14
Query: 123 KVDI 126
K+D+
Sbjct: 13 KIDL 2
>33374
Length = 489
Score = 71.6 bits (174), Expect(2) = 1e-17, Method: Compositional matrix adjust.
Identities = 35/101 (34%), Positives = 61/101 (60%), Gaps = 3/101 (2%)
Frame = +1
Query: 59 IKFNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCE-NIPI 117
+KF +WDTAGQE++ L YY AQ AI+++D+T++ T+ W ++L R NI I
Sbjct: 175 VKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQDTFGRAKTWVKELQRQASPNIVI 354
Query: 118 VLCGNKVDIKDRKVK--AKSIVFHRKKNLQYYDISAKSNYN 156
L GNK D+ ++++ ++ + + +L + + SAK+ N
Sbjct: 355 ALAGNKADLANKRMVEFEEAQAYAEENSLLFMETSAKTAMN 477
Score = 34.3 bits (77), Expect(2) = 1e-17, Method: Compositional matrix adjust.
Identities = 18/43 (41%), Positives = 28/43 (65%)
Frame = +2
Query: 2 AAQGEPQVQFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLG 44
A QG+ QFKLVL+G+ GK++ V R + G+F + +T+G
Sbjct: 8 ATQGKI-CQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIG 133
>34468
Length = 1502
Score = 84.7 bits (208), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 54/193 (27%), Positives = 94/193 (48%), Gaps = 11/193 (5%)
Frame = +1
Query: 6 EPQVQ---FKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFN 62
E Q Q FK++++GD GKT R G+F K AT+GV+ + +K
Sbjct: 472 EKQTQRRIFKIIVIGDSNVGKTCLTYRFCLGKFPDKTEATIGVDFREKSIQVDSEHLKLQ 651
Query: 63 VWDTAGQEKF-GGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVR--VCENIPIVL 119
+WDTAGQE+F + YY + ++D+T +++N+P W + R + + IP +L
Sbjct: 652 LWDTAGQERFRKSMVQHYYRNVHAVVFVYDMTKMSSFENMPAWIEECDRHNLTKYIPRIL 831
Query: 120 CGNKVDIKDRKVKAKSIV--FHRKKNLQYYDISAKSNY---NFEKPFLWLARKLIGDPNL 174
GNK D+ +R ++ F N+ ++ SAK + + + F+ +A KL +
Sbjct: 832 VGNKCDVVERIAVNTNLAQKFADAHNMPLFETSAKDDEKANHVDAIFMTVAHKLKXSKPM 1011
Query: 175 EFVAMPALAPPEV 187
+ + P +V
Sbjct: 1012MPAHLSEMVPGDV 1050
>13901
Length = 962
Score = 83.2 bits (204), Expect = 7e-17, Method: Compositional matrix adjust.
Identities = 38/100 (38%), Positives = 60/100 (60%), Gaps = 1/100 (1%)
Frame = -3
Query: 6 EPQVQFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFH-TNRGPIKFNVW 64
+V FK++++GD GKT+FV+R++ F + Y T+GV+ V +++ IK +W
Sbjct: 300 SEEVLFKVIIIGDPTVGKTSFVQRYVNDSFRRDYKMTIGVDFALKVIRWSDKCNIKLQLW 121
Query: 65 DTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNW 104
D AGQE+F + YY A I+MFD+T + TY+N W
Sbjct: 120 DIAGQERFTSMTRVYYKDAHACIVMFDLTQKNTYQNAIRW 1
>07465
Length = 1103
Score = 79.0 bits (193), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 44/154 (28%), Positives = 78/154 (50%), Gaps = 4/154 (2%)
Frame = +3
Query: 24 TTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQEKFGGLRDGYYIQA 83
++ ++R+ G F K Y T+GV+ ++ +WDTAGQE+F + YY A
Sbjct: 240 SSMIQRYCKGIFTKDYKKTIGVDFLERQIEVGGEDVRLMLWDTAGQEEFDAITKAYYRGA 419
Query: 84 QCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLCGNKVDIKD----RKVKAKSIVFH 139
Q ++ F R +++ + W R + I +V+ NK+D+ D R +A+++
Sbjct: 420 QACVLAFSTVDRDSFEALETWKRKVEDEVGEIGMVIVQNKIDLIDDAVVRPEEAENLA-- 593
Query: 140 RKKNLQYYDISAKSNYNFEKPFLWLARKLIGDPN 173
+K L++Y S K N N ++ F +LA K + N
Sbjct: 594 KKLRLRFYRTSVKENMNVDEVFRYLADKYLHQLN 695
>11728
Length = 635
Score = 79.0 bits (193), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 41/121 (33%), Positives = 65/121 (53%), Gaps = 1/121 (0%)
Frame = -1
Query: 11 FKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQE 70
K V+VGDG GKT + + T F +Y+ T+ + + + PI +WDTAGQE
Sbjct: 488 IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTV-FDNYSANVMVDSKPINLGLWDTAGQE 312
Query: 71 KFGGLRDGYYIQAQCAIIMFDVTSRVTYKNV-PNWHRDLVRVCENIPIVLCGNKVDIKDR 129
+ LR Y Q +I F + S +++NV W+ ++ C N PI+L G K+D+++
Sbjct: 311 DYDRLRPLSYPQTDVFLICFSLISPASFENVKAKWYPEVSHHCPNTPIILVGTKLDLRED 132
Query: 130 K 130
K
Sbjct: 131 K 129
>26083
Length = 432
Score = 78.6 bits (192), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 37/120 (30%), Positives = 64/120 (53%), Gaps = 1/120 (0%)
Frame = +1
Query: 5 GEPQVQFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVW 64
G P +FKLV +G+ GKT+ + R + F+ Y AT+G++ + I+ +W
Sbjct: 61 GNPLRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTIRLQLW 240
Query: 65 DTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDL-VRVCENIPIVLCGNK 123
DTAGQE+F L Y + A++++D+T+ ++ W D+ ++ I+L GNK
Sbjct: 241 DTAGQERFRSLIPSYIRDSSVAVVVYDITNANSFHQTSKWIDDVRTERGSDVIIMLVGNK 420
>11257
Length = 1102
Score = 72.8 bits (177), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 35/113 (30%), Positives = 64/113 (56%), Gaps = 7/113 (6%)
Frame = -2
Query: 63 VWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCE-----NIPI 117
+WDTAGQE++ LR +Y C ++ F V + + +++ +W+ + V + + P
Sbjct: 1014 IWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLKSLQSLSDWYDEFVNYADIQDSASFPF 835
Query: 118 VLCGNKVDIKDRKVKAKSIV--FHRKKNLQYYDISAKSNYNFEKPFLWLARKL 168
V+ GNK DI++R+V ++ NL Y++ SAK + N ++ FL + R+L
Sbjct: 834 VIIGNKADIEEREVSSEDAYNWCRTHGNLPYFETSAKDSLNVQQAFLAVVRRL 676
>19006
Length = 568
Score = 72.4 bits (176), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 39/118 (33%), Positives = 63/118 (53%), Gaps = 1/118 (0%)
Frame = -2
Query: 12 KLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQEK 71
KLV+VGDG GKT + +F + YV T+ E + + ++ +WDTAGQE
Sbjct: 432 KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTV-FENYVADIEVDSKQVELALWDTAGQED 256
Query: 72 FGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPN-WHRDLVRVCENIPIVLCGNKVDIKD 128
+ LR Y ++ F + S + +N+P W ++ C N+PI+L GNK D+++
Sbjct: 255 YDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVRHFCPNVPIILVGNKKDLRN 82
>07580
Length = 921
Score = 62.0 bits (149), Expect(2) = 1e-12, Method: Compositional matrix adjust.
Identities = 31/112 (27%), Positives = 62/112 (55%), Gaps = 4/112 (3%)
Frame = +3
Query: 61 FNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRV--CENIPIV 118
+ DTAG E+F +RD Y Q ++ + +T++ T+ ++ ++RV +++P++
Sbjct: 210 LEILDTAGTEQFTAMRDLYMKNGQGFLLAYSITAQSTFNDLQELREQILRVKDTDDVPML 389
Query: 119 LCGNKVDIKDRKV--KAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKL 168
L GNK D++D +V K + R + + + SAK+ N + F+ L R++
Sbjct: 390 LVGNKCDLEDERVVGKDQGQGLARSFSCAFLETSAKARINVNEIFMDLVRQI 545
Score = 27.3 bits (59), Expect(2) = 1e-12, Method: Compositional matrix adjust.
Identities = 11/30 (36%), Positives = 19/30 (63%)
Frame = +2
Query: 6 EPQVQFKLVLVGDGGTGKTTFVKRHLTGEF 35
E ++KLV++G GG GK+ + + G+F
Sbjct: 47 ETMREYKLVVLGSGGVGKSALTVQFVQGDF 136
>30760
Length = 596
Score = 66.2 bits (160), Expect = 9e-12, Method: Compositional matrix adjust.
Identities = 44/162 (27%), Positives = 78/162 (48%), Gaps = 8/162 (4%)
Frame = -1
Query: 12 KLVLVGDGGTGKTTFVK--RHLTGEFEKKYVATLGVEVHPLVFHT--NRGPIKFNVWDTA 67
K ++ GD G GK++ + + F K Y T GVEV + + +R ++ ++D+A
Sbjct: 524 KCIVTGDSGVGKSSICQVFHSDSAHFPKNYSMTTGVEVLVKLVNIPDSRDQVELYLFDSA 345
Query: 68 GQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCEN--IPIVLCGNKVD 125
G+E F ++ Q ++++DVT ++ W + N IP VL NK D
Sbjct: 344 GKEIFSENVTKFWDQPSVVMVVYDVTDETSFSGCVRWLERVRAAKPNTVIPGVLVANKTD 165
Query: 126 IKDRK--VKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLA 165
+ +R+ + + + L+Y++ SAK N + PF LA
Sbjct: 164 LDERRRVSRKEGKDLAQSHGLEYFECSAKEMQNTDTPFFCLA 39
>33794
Length = 779
Score = 63.5 bits (153), Expect = 6e-11, Method: Compositional matrix adjust.
Identities = 33/121 (27%), Positives = 65/121 (53%), Gaps = 2/121 (1%)
Frame = -1
Query: 59 IKFNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIV 118
+K +WDT+GQ +F + Y AQ I+++D+T++ ++ + W +++ IP V
Sbjct: 650 VKLQIWDTSGQGRFCTIIRSYSRGAQGIILVYDITNKWSFDGIDRWLKEVEEHAPGIPKV 471
Query: 119 LCGNKVDIK-DRKVKAKSI-VFHRKKNLQYYDISAKSNYNFEKPFLWLARKLIGDPNLEF 176
L GN++ + R+V AK + + N+ ++IS ++N + F LAR + +E
Sbjct: 470 LVGNRLHLAYKRQVAAKQAETYASRNNMSCFEISPLCDFNIRESFCELARMALHRNGMEH 291
Query: 177 V 177
+
Sbjct: 290 I 288
>13745
Length = 1045
Score = 63.5 bits (153), Expect = 6e-11, Method: Compositional matrix adjust.
Identities = 34/108 (31%), Positives = 59/108 (54%), Gaps = 7/108 (6%)
Frame = +2
Query: 69 QEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLV-----RVCENIPIVLCGNK 123
QE+F L +Y A C ++++DVT+ ++KN+ +W + + R E+ P V+ GNK
Sbjct: 2 QERFQSLGVAFYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPEHFPFVVLGNK 181
Query: 124 VDIKDRKVKAKSIV--FHRKKNLQYYDISAKSNYNFEKPFLWLARKLI 169
VD+ +R+V + K ++ YY+ SAK N E F +A+ +
Sbjct: 182 VDLDNRQVSTRRAQQWCQSKNDIPYYETSAKEGINVEMAFQTIAKNAL 325
>12339
Length = 578
Score = 61.6 bits (148), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 35/109 (32%), Positives = 58/109 (53%), Gaps = 7/109 (6%)
Frame = -2
Query: 69 QEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLV-----RVCENIPIVLCGNK 123
QE+F L +Y A C I+++DVT T+ ++ +W R+ + R E+ P V+ GNK
Sbjct: 577 QERFQSLGVAFYRGADCCILVYDVTEXKTFDSLDSWQREFLNQASPRDPEHFPFVVIGNK 398
Query: 124 VDIKDRKVKAK--SIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLIG 170
+D+ +R V AK K + Y++ SAK N E+ F +A+ +
Sbjct: 397 IDLDNRVVTAKRGQGWCSTKGGIPYFETSAKEAINVEQAFQTVAKNALA 251
>19656
Length = 428
Score = 58.9 bits (141), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 33/102 (32%), Positives = 51/102 (50%), Gaps = 1/102 (0%)
Frame = +3
Query: 12 KLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQEK 71
K V+VGDG GKT + + T F +Y+ T+ V R P+ +WDTAGQE
Sbjct: 117 KCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGR-PVNLGLWDTAGQED 293
Query: 72 FGGLRDGYYIQAQCAIIMFDVTSRVTYKNV-PNWHRDLVRVC 112
+ LR Y Q ++ F V S +++N+ W+ ++ C
Sbjct: 294 YDRLRPLSYPQTDVFLLCFSVASPASFENIRAKWYPEVNHHC 419
>33380
Length = 282
Score = 57.8 bits (138), Expect = 4e-09, Method: Compositional matrix adjust.
Identities = 29/82 (35%), Positives = 48/82 (58%), Gaps = 1/82 (1%)
Frame = +3
Query: 51 VFHTNRGPIKFNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDL-V 109
VF ++ +K +WDTAGQE++ + YY A I+M+DVT+ ++ V +W +
Sbjct: 39 VFRQDK-RVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDVTNEESFNAVQDWCTQIKT 215
Query: 110 RVCENIPIVLCGNKVDIKDRKV 131
+N +VL GNK D++D +V
Sbjct: 216 YSWDNAQVVLVGNKCDLEDERV 281
>35581
Length = 364
Score = 54.7 bits (130), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 28/88 (31%), Positives = 43/88 (48%), Gaps = 1/88 (1%)
Frame = +2
Query: 5 GEPQVQFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPI-KFNV 63
G + FK VL+GD G GKT + R T +F + +L G + ++
Sbjct: 29 GNDTLYFKCVLLGDAGVGKTCLLNRLATDKFLDSPLTSLTTASLLTTVTLTSGVMASVDL 208
Query: 64 WDTAGQEKFGGLRDGYYIQAQCAIIMFD 91
WDTAGQE++ L YY + +I++D
Sbjct: 209 WDTAGQERYRSLTSSYYRDTKAVLIVYD 292
>01398
Length = 1421
Score = 52.4 bits (124), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 34/103 (33%), Positives = 59/103 (57%), Gaps = 5/103 (4%)
Frame = -2
Query: 69 QEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWH---RDLVRVCENIPIVLCGNKVD 125
QE+F + YY + II++D+T R T++N+ W+ R+ + + I +VL G+K D
Sbjct: 1420 QERFRSITRSYYRNSVGVIIVYDITKRSTFENLKQWYEEARNHIEPHKAIFLVL-GHKSD 1244
Query: 126 IKD-RKVKAKS-IVFHRKKNLQYYDISAKSNYNFEKPFLWLAR 166
+D R+V A+ F L++++ SAKS +N E F +A+
Sbjct: 1243 REDARQVTAREGRRFAEMHGLKFFETSAKSGHNIEDVFAQIAK 1115
>32723
Length = 384
Score = 52.4 bits (124), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 31/108 (28%), Positives = 53/108 (49%), Gaps = 3/108 (2%)
Frame = +2
Query: 69 QEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNW-HRDLVRVCENIPIVLCGNKVDIK 127
QE+F + YY A I+++DV S+ +Y+++P W H + + L GNK+D
Sbjct: 2 QERFRSITQSYYRSANALILVYDVCSQQSYESLPQWIHEIELYAGTKVLAFLVGNKIDQT 181
Query: 128 DRKVKAKSI--VFHRKKNLQYYDISAKSNYNFEKPFLWLARKLIGDPN 173
D++ I F + +++ + SAK N EK F +A +L
Sbjct: 182 DKREIPTHIGKEFAERYEMRFLETSAKEADNVEKLFSTIAYQLTAQAQ 325
>26536
Length = 829
Score = 52.4 bits (124), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 33/114 (28%), Positives = 56/114 (49%), Gaps = 4/114 (3%)
Frame = +2
Query: 59 IKFNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPI- 117
+ + DTAGQE++ +R+ Y I+++ VT +++ R L R + I
Sbjct: 128 VSWTFLDTAGQEEYSSMREHYTRSGDGFIVVYSVTDVTSFQEAEAVFRWLTRFQDETSIH 307
Query: 118 -VLCGNKVDI-KDRKVK-AKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKL 168
VLCGNK D+ DRKV + + + Y++ SAK+ N + + L R +
Sbjct: 308 AVLCGNKTDLTSDRKVTPEEGRKMADRLGMLYFETSAKTGDNVSQVYHGLLRSI 469
>13750
Length = 503
Score = 51.6 bits (122), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 34/148 (22%), Positives = 74/148 (50%), Gaps = 9/148 (6%)
Frame = -2
Query: 23 KTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGP---IKFNVWDTAGQEKFGGLRDGY 79
KT ++R+ G F + + T+ V F+ +R +++ +WDT G E + L +
Sbjct: 502 KTCLLRRYQKGFFMDRTMPTIAVLCSE--FNESRTDPLNVRYTLWDTGGAETYRSLWVSH 329
Query: 80 YIQAQCAIIMFDVTSRVTYKNVPN-WHRDLVRVCENIP---IVLCGNKVDIKDRKVKA-- 133
+ AQ A++++DVT ++ W + L++ NIP ++ G+K D+++ +V +
Sbjct: 328 FRGAQVALLVYDVTCEWSFLTATTVWRKALMK---NIPEAQVIFVGSKTDLEENRVISTE 158
Query: 134 KSIVFHRKKNLQYYDISAKSNYNFEKPF 161
+ F + +++ S+ + N + F
Sbjct: 157 RGQAFATQCGYTFFETSSVTGKNVDAVF 74
>31291
Length = 446
Score = 51.6 bits (122), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 31/117 (26%), Positives = 54/117 (46%), Gaps = 16/117 (13%)
Frame = -1
Query: 61 FNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVP-NWHRDLVRVCENIPIVL 119
+WDTAGQE + LR Y ++ F + S + KNV W+ ++ ++PIVL
Sbjct: 446 LQLWDTAGQEDYDRLRPLAYPNTDVFMLXFSLMSEASMKNVKVKWYPEIRHHDPHVPIVL 267
Query: 120 CGNKVDIKDRKVKAKSIVFHRK---------------KNLQYYDISAKSNYNFEKPF 161
G K+D++ K + + R+ K +Y++ S+K+ N + F
Sbjct: 266 VGTKLDLRQDKEAVRKLRSSRQDPVSSNQGNDLAKAIKAKRYFECSSKTQENLKTAF 96
>27191
Length = 443
Score = 50.8 bits (120), Expect = 4e-07, Method: Compositional matrix adjust.
Identities = 26/103 (25%), Positives = 55/103 (53%), Gaps = 1/103 (0%)
Frame = +1
Query: 23 KTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQEKFGGLRDGYYIQ 82
KT +K +F + Y T+GV+ + N ++ ++WD +G ++ +R+ Y
Sbjct: 1 KTCLIKHFCESKFNQGYQPTVGVDYGFKIQTVNGVDMRVHMWDLSGSNEYLDVRNELYTG 180
Query: 83 AQCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPI-VLCGNKV 124
+ I+FDV++ +++ + +W R++ R P+ V+ GN+V
Sbjct: 181 SDAIFIVFDVSNTPSFEALDSWLREINRFATGSPLNVIVGNRV 309
>00858
Length = 1658
Score = 50.4 bits (119), Expect = 5e-07, Method: Compositional matrix adjust.
Identities = 30/115 (26%), Positives = 60/115 (52%), Gaps = 7/115 (6%)
Frame = -2
Query: 61 FNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRV--CENIPIV 118
++ DTAGQE+ +RD + + +F V + +++++ + + RV + +P+V
Sbjct: 1441 LDILDTAGQEEXSAMRDQCMRTGEGFLCVFAVXNLKSFEDINQYREQIKRVKDADEVPMV 1262
Query: 119 LCGNKVD-----IKDRKVKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKL 168
L GNKVD ++ R+ K + ++H + Y + SAK+ + F L R++
Sbjct: 1261 LVGNKVDLPIRNVEQRQGKHMAELYH----IPYVETSAKTRQGVDDAFYTLVREI 1109
>19046
Length = 445
Score = 49.7 bits (117), Expect = 9e-07, Method: Compositional matrix adjust.
Identities = 27/88 (30%), Positives = 51/88 (57%), Gaps = 4/88 (4%)
Frame = -2
Query: 69 QEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRV--CENIPIVLCGNKVD- 125
QE+F +R+ Y + +++F VT +++N+ N+H ++RV ++ P++LC NKVD
Sbjct: 444 QEEFSAMREQYMRKGDGFLLVFSVTDFRSFENMANFHTQILRVKDRDSYPMILCANKVDL 265
Query: 126 IKDRKVKAKSIV-FHRKKNLQYYDISAK 152
+ RKV + + + + Y + SAK
Sbjct: 264 VHQRKVSEEQVRDLATRLRIPYIETSAK 181
>29380
Length = 853
Score = 47.4 bits (111), Expect = 5e-06, Method: Compositional matrix adjust.
Identities = 32/93 (34%), Positives = 52/93 (55%), Gaps = 6/93 (6%)
Frame = -2
Query: 83 AQCAIIMFDVTSRVTYKNVPNWHRDLVRV-CENIPIVLCGNKVDI--KDRKVK---AKSI 136
A AII++DV T+ W ++L + E++ I+L GNKVD+ + R V A+S
Sbjct: 852 ASAAIIVYDVNIADTFSRALAWVKELRQQNTESVLIILAGNKVDLATQHRAVSFEDAQS- 676
Query: 137 VFHRKKNLQYYDISAKSNYNFEKPFLWLARKLI 169
F R+ L + ++SAK+ + F+ LA +LI
Sbjct: 675 -FARENGLLFAEVSAKTGMAVNEIFMTLANQLI 580
>24619
Length = 509
Score = 47.0 bits (110), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 30/109 (27%), Positives = 56/109 (51%), Gaps = 5/109 (4%)
Frame = -2
Query: 69 QEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRV--CENIPIVLCGNKVD- 125
QE+F +R+ Y + +++F V +++N+ N+H ++RV + P++LC NKVD
Sbjct: 508 QEEFSAMREQYMRKGDGFLLVFSVIDYQSFENMVNFHTQILRVKDRDTYPMILCANKVDL 329
Query: 126 IKDRKVKAKSIV-FHRKKNLQYYDISAKS-NYNFEKPFLWLARKLIGDP 172
+ RKV + + + + Y + SAK N + F + R + P
Sbjct: 328 VHQRKVSEEQVRDLATRLRIPYIETSAKDPPLNVDLAFHQVVRVIRAQP 182
>00552
Length = 455
Score = 42.0 bits (97), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 19/65 (29%), Positives = 34/65 (52%)
Frame = -3
Query: 45 VEVHPLVFHTNRGPIKFNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNW 104
V P V+H +WDTAGQE++ LR +Y C ++ F V + + +++ +W
Sbjct: 180 VAASPDVWH-------HGIWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLKSLQSLSDW 22
Query: 105 HRDLV 109
+ + V
Sbjct: 21 YDEFV 7
Score = 37.0 bits (84), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 15/36 (41%), Positives = 26/36 (72%)
Frame = -1
Query: 11 FKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVE 46
K+VL+GDGG GK++ + R ++ +F+ + T+GVE
Sbjct: 443 LKVVLLGDGGVGKSSLMNRFVSNKFDAQSFHTIGVE 336
>36482
Length = 686
Score = 41.2 bits (95), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 32/111 (28%), Positives = 53/111 (47%), Gaps = 5/111 (4%)
Frame = +2
Query: 29 RHLTGEFEKKYVATLGVEVHPLVFHT--NRGPIKFNVWDTAGQEKFGGLRDGYYIQAQCA 86
R LT F +Y TL +HT ++ + DTAGQ + ++GY + A C
Sbjct: 11 RFLTRRFIGEYCPTLE---SVYKYHTVIEDDDVRLEILDTAGQGTYP-WKEGYALWADCF 178
Query: 87 IIMFDVTSRVTYKNVPNWHRDL--VRVCENIPIVLCGNKVD-IKDRKVKAK 134
+ ++ + R +Y+ + R + VR ++ VL NK D + DR+V K
Sbjct: 179 VFVYSINDRQSYEELVQVKRQVESVRKSTSLTAVLAANKTDLLHDRQVTQK 331
>08153
Length = 1703
Score = 39.3 bits (90), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 25/86 (29%), Positives = 39/86 (45%)
Frame = +1
Query: 10 QFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQ 69
+ ++++VG GKTT + + GE + T+G V + + I F VWD GQ
Sbjct: 82 EVRILMVGLDAAGKTTILYKLKLGEIVTT-IPTIGFNVETVEYKN----ISFTVWDVGGQ 246
Query: 70 EKFGGLRDGYYIQAQCAIIMFDVTSR 95
+K L Y+ Q I + D R
Sbjct: 247 DKIRPLWRHYFQNTQGLIFVVDSNDR 324
>14775
Length = 380
Score = 38.1 bits (87), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 21/74 (28%), Positives = 40/74 (54%), Gaps = 3/74 (4%)
Frame = -2
Query: 23 KTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGP---IKFNVWDTAGQEKFGGLRDGY 79
KT ++R+ G F + + T+ V F+ +R +++ +WDT G E + L +
Sbjct: 379 KTCLLRRYQKGFFMDRTMPTIAVLCSE--FNESRTDPLNVRYTLWDTGGAETYRSLWVSH 206
Query: 80 YIQAQCAIIMFDVT 93
+ AQ A++++DVT
Sbjct: 205 FRGAQVALLVYDVT 164
>09204
Length = 1051
Score = 37.0 bits (84), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 24/101 (23%), Positives = 49/101 (48%), Gaps = 6/101 (5%)
Frame = -3
Query: 71 KFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLCGNKVDI---- 126
++ + YY A+ AI+ FD+T + ++ + W +L + E + +CG K D+
Sbjct: 1049 RYEAMSRIYYRGAKAAILCFDLTDKSSFDRIRFWIGELRQHEEECKLYICGTKFDLVHDD 870
Query: 127 KDRKVKAKSIVFHRKKNL--QYYDISAKSNYNFEKPFLWLA 165
+R+ +S+ + + Y+ S+ + N EK F +A
Sbjct: 869 PERRAVPRSVAKALADDCMAEIYETSSMTGDNIEKLFTKIA 747
>09827
Length = 1201
Score = 36.6 bits (83), Expect = 0.008, Method: Compositional matrix adjust.
Identities = 38/168 (22%), Positives = 68/168 (40%), Gaps = 10/168 (5%)
Frame = -3
Query: 11 FKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQE 70
++++VG GKTT + + GE + T+G V + + I F VWD GQ+
Sbjct: 1112 MRILMVGLDAAGKTTILYKLKLGEIVTT-IPTIGFNVETVEYKN----ISFTVWDVGGQD 948
Query: 71 KFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRV-----CENIPIVLCGNKVD 125
K L Y+ Q I + D + + V +L R+ + +++ NK D
Sbjct: 947 KIRPLWRHYFQNTQGLIFVVDSNDK---ERVQEAREELTRMLNEDELRDAVLLVFANKQD 777
Query: 126 IKDRKVKA---KSIVFHRKKNLQYY--DISAKSNYNFEKPFLWLARKL 168
+ A + + H +N +Y A + + WL+ +L
Sbjct: 776 LPHAMATAEITEKLGLHGLRNRTWYIQSTCATTGDGLYEGLDWLSNQL 633
>33605
Length = 888
Score = 35.4 bits (80), Expect = 0.019, Method: Compositional matrix adjust.
Identities = 25/91 (27%), Positives = 41/91 (45%)
Frame = +1
Query: 6 EPQVQFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWD 65
+ + + +L+++G GKTT +K+ GE TLG + L +RG K NVWD
Sbjct: 484 QKEKEVRLLMLGLDNAGKTTILKK-FNGEDIDTISPTLGFNIKTL---EHRG-FKLNVWD 648
Query: 66 TAGQEKFGGLRDGYYIQAQCAIIMFDVTSRV 96
GQ+ Y+ + + D R+
Sbjct: 649 VGGQQSLRSYWRNYFESTDGLVWVVDSADRM 741
>10708
Length = 2775
Score = 35.4 bits (80), Expect = 0.019, Method: Compositional matrix adjust.
Identities = 14/44 (31%), Positives = 24/44 (54%)
Frame = -2
Query: 59 IKFNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVP 102
++ +WDTAGQE + LR Y ++ F + S + +N+P
Sbjct: 2723 VELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIP 2592
Score = 30.4 bits (67), Expect = 0.52, Method: Compositional matrix adjust.
Identities = 14/48 (29%), Positives = 28/48 (58%)
Frame = -3
Query: 81 IQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLCGNKVDIKD 128
+ + CA + +T+ T ++ W ++ C N+PI+L GNK D+++
Sbjct: 2647 MSSLCASPLTALTAWRT--SLKKWTPEVRHFCPNVPIILVGNKKDLRN 2510
>20290
Length = 1550
Score = 32.7 bits (73), Expect = 0.10, Method: Compositional matrix adjust.
Identities = 19/46 (41%), Positives = 26/46 (56%), Gaps = 3/46 (6%)
Frame = +1
Query: 13 LVLVGDGGTGKTTFVKRHLTGEFE---KKYVATLGVEVHPLVFHTN 55
LVL+G+ GTGKTTF+ R L G + + + L + P FH N
Sbjct: 787 LVLLGENGTGKTTFI-RMLAGNLQPDGEVELPMLNISYKPQKFHRN 921
>10862
Length = 2896
Score = 32.3 bits (72), Expect = 0.16, Method: Compositional matrix adjust.
Identities = 15/36 (41%), Positives = 18/36 (50%)
Frame = -3
Query: 60 KFNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSR 95
+FNVWD GQ+K L YY Q I + D R
Sbjct: 2483 QFNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADR 2376
>13795
Length = 642
Score = 29.6 bits (65), Expect = 0.97, Method: Compositional matrix adjust.
Identities = 17/33 (51%), Positives = 20/33 (60%), Gaps = 1/33 (3%)
Frame = -1
Query: 1 MAAQGEPQVQFK-LVLVGDGGTGKTTFVKRHLT 32
M A E Q Q K L ++GDGGT T+FV LT
Sbjct: 204 MTAGSEVQAQAKRLQILGDGGTQPTSFVNSVLT 106
>18248
Length = 466
Score = 28.9 bits (63), Expect = 1.5, Method: Compositional matrix adjust.
Identities = 13/24 (54%), Positives = 19/24 (79%)
Frame = +3
Query: 13 LVLVGDGGTGKTTFVKRHLTGEFE 36
+V++G+ GTGKTTF+K L G+ E
Sbjct: 108 IVMLGENGTGKTTFIKM-LAGKLE 176
>33029
Length = 1133
Score = 28.9 bits (63), Expect = 1.7, Method: Compositional matrix adjust.
Identities = 11/30 (36%), Positives = 16/30 (53%)
Frame = +1
Query: 77 DGYYIQAQCAIIMFDVTSRVTYKNVPNWHR 106
D +I CAI M ++ ++KN P W R
Sbjct: 682 DCKFILGTCAIFMQQTDTKPSHKNTPQWAR 771
>11357
Length = 1307
Score = 27.3 bits (59), Expect = 4.6, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 27/42 (64%), Gaps = 4/42 (9%)
Frame = -2
Query: 145 QYYDISA---KSNYNFEKPFLWLAR-KLIGDPNLEFVAMPAL 182
++YD S+ K+NY+F+K F+W + +L +LE++ + L
Sbjct: 733 EHYDFSSCISKNNYSFKKGFIWFSCIQLFKRGSLEYMLVFVL 608
>02253
Length = 1110
Score = 26.9 bits (58), Expect = 6.0, Method: Compositional matrix adjust.
Identities = 18/61 (29%), Positives = 26/61 (42%), Gaps = 1/61 (1%)
Frame = +3
Query: 38 KYVATLG-VEVHPLVFHTNRGPIKFNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRV 96
+Y+A L + VH V + KFN+ DT+ + F +I C T RV
Sbjct: 213 EYLAQLDKLFVHQKVERNDLASTKFNIMDTSQKPAFEAAESSSFISRLCCFGFRGFTYRV 392
Query: 97 T 97
T
Sbjct: 393 T 395
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000376176 | hsapiens_gene_ensembl | GTP-binding
nuclear protein Ran (GTPase Ran) (Ras-like protein TC4) (Androgen
receptor-associated protein 24). [Source:Uniprot/SWISSPROT;Acc:P62826]
(236 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
01972 340 e-104
34359 224 4e-91
08428 92 2e-19
14456 89 1e-18
05468 89 2e-18
17511 87 6e-18
33374 72 2e-17
34468 85 3e-17
13901 83 8e-17
26083 79 1e-15
11728 79 1e-15
07465 79 1e-15
19006 73 1e-13
11257 72 1e-13
07580 62 1e-12
30760 66 1e-11
33794 64 6e-11
13745 63 8e-11
12339 62 2e-10
19656 59 2e-09
33380 58 4e-09
35581 55 3e-08
01398 53 1e-07
32723 52 1e-07
26536 52 2e-07
31291 52 3e-07
13750 51 3e-07
27191 51 4e-07
00858 50 6e-07
19046 50 1e-06
29380 47 7e-06
24619 47 7e-06
00552 42 2e-04
36482 42 3e-04
08153 40 0.001
14775 38 0.003
09204 37 0.007
09827 37 0.008
33605 36 0.014
10708 35 0.019
20290 33 0.11
10862 32 0.15
13795 30 1.1
18248 29 1.8
33029 29 1.9
11357 27 4.8
02253 27 6.2
>01972
Length = 2359
Score = 340 bits (871), Expect(2) = e-104, Method: Compositional matrix adjust.
Identities = 157/180 (87%), Positives = 169/180 (93%)
Frame = +3
Query: 57 KKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRV 116
KKYVATLGVEVHPL+FHT+RG +KFNVWDTAGQEKFGGLRDGYYIQ QCA+IMFDVTSRV
Sbjct: 381 KKYVATLGVEVHPLLFHTSRGKLKFNVWDTAGQEKFGGLRDGYYIQGQCAVIMFDVTSRV 560
Query: 117 TYKNVPNWHRDLVRVCENIPIVLCGNKVDIKDRKVKAKSIVFHRKKNLQYYDISAKSNYN 176
TYKNVPNWHRDLVRVCENIPIVLCGNKVDIKDRKVKAK+IVFHRKKNLQYYDISAKSNYN
Sbjct: 561 TYKNVPNWHRDLVRVCENIPIVLCGNKVDIKDRKVKAKAIVFHRKKNLQYYDISAKSNYN 740
Query: 177 FEKPFLWLARKLIGDPNLEFVAMPALAPPEVVMDPALAAQYEHDLEVAQTTALPDEDDDL 236
FEKPFLWLARKL+GDPNLEFV MPAL PPEV MD LA +YE +L+VAQ ALPD+D+D+
Sbjct: 741 FEKPFLWLARKLVGDPNLEFVEMPALLPPEVAMDAVLAKKYEEELKVAQEVALPDDDEDI 920
Score = 56.2 bits (134), Expect(2) = e-104, Method: Compositional matrix adjust.
Identities = 29/41 (70%), Positives = 31/41 (75%)
Frame = +1
Query: 17 RNAAMAAQGEPQVQFKLVLVGDGGTGKTTFVKRHLTGEFEK 57
RN M E + FKLVLVGDGG GKTTFVKRH+TGEFEK
Sbjct: 274 RNQRM----EQEPTFKLVLVGDGGVGKTTFVKRHVTGEFEK 384
>34359
Length = 1042
Score = 224 bits (571), Expect(2) = 4e-91, Method: Compositional matrix adjust.
Identities = 109/136 (80%), Positives = 116/136 (85%)
Frame = +3
Query: 30 QFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQ 89
FKLVLVG VKRH+TG KKYVATLGVEVHPL F+T+RG ++FNVWDTAGQ
Sbjct: 51 NFKLVLVGGRWEWANNIVKRHVTGS*-KKYVATLGVEVHPLQFNTSRGLLRFNVWDTAGQ 227
Query: 90 EKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLCGNKVDIKDR 149
EKFGGLRDGYYIQ CAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLCGNKVDIKDR
Sbjct: 228 EKFGGLRDGYYIQGTCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLCGNKVDIKDR 407
Query: 150 KVKAKSIVFHRKKNLQ 165
KVKAK+IVFHRK+
Sbjct: 408 KVKAKAIVFHRKRTCS 455
Score = 127 bits (320), Expect(2) = 4e-91, Method: Compositional matrix adjust.
Identities = 58/79 (73%), Positives = 68/79 (86%)
Frame = +2
Query: 158 FHRKKNLQYYDISAKSNYNFEKPFLWLARKLIGDPNLEFVAMPALAPPEVVMDPALAAQY 217
++KNLQYYDISAKSNYNFEKPFLWLARKL+GDPNL FV MPAL PPEV MDP +A +Y
Sbjct: 431 LSQEKNLQYYDISAKSNYNFEKPFLWLARKLVGDPNLXFVEMPALLPPEVAMDPNMAKRY 610
Query: 218 EHDLEVAQTTALPDEDDDL 236
E +L+VAQ ALPD+D+D+
Sbjct: 611 EDELKVAQEVALPDDDEDI 667
>08428
Length = 1109
Score = 92.4 bits (228), Expect = 2e-19, Method: Compositional matrix adjust.
Identities = 53/160 (33%), Positives = 87/160 (54%), Gaps = 3/160 (1%)
Frame = -3
Query: 32 KLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQEK 91
K+ L+GD G GK++ V R +TG + +T+G + +F +WDTAGQEK
Sbjct: 1065 KVCLLGDSGVGKSSIVLRFVTGSYRPSQESTIGASFMSKSLVVDGAGYRFQIWDTAGQEK 886
Query: 92 FGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVC-ENIPIVLCGNKVDIKDRK 150
F L YY A A+I++DVT T+K+V +W ++L NI + + GNK D+++ +
Sbjct: 885 FRALAPMYYRGAAAAVIVYDVTRPRTFKSVKSWIQELRSFGPPNIVLAIAGNKCDLEELR 706
Query: 151 --VKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKL 188
V+ + + + + + SA + N E+ F LAR+L
Sbjct: 705 EVVEKDAQEYASSISAIFGETSAMTAVNVEEMFTELARQL 586
>14456
Length = 1867
Score = 89.4 bits (220), Expect = 1e-18, Method: Compositional matrix adjust.
Identities = 49/158 (31%), Positives = 83/158 (52%), Gaps = 8/158 (5%)
Frame = -1
Query: 39 GGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQEKFGGLRDG 98
GG GK++ + R ++ +F+ + T+GVE + +WDTAGQE+F LR
Sbjct: 1114 GGVGKSSLMNRFVSNKFDAQSFHTIGVEFLNKDVVVDDETYTMQIWDTAGQERFKSLRTP 935
Query: 99 YYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCE-----NIPIVLCGNKVDIKDRKV-- 151
+Y A C ++ F V S +++N+ W ++ + + P V+ GNK+D++ R+V
Sbjct: 934 FYRGADCCLLTFSVDSMQSFRNLSMWRKEFLYYADIQDGVTFPFVVLGNKIDVEGRQVTN 755
Query: 152 -KAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKL 188
+A+S N Y++ SAK N EK FL ++L
Sbjct: 754 EEARSWC-TANSNAPYFETSAKDATNVEKAFLAAVQRL 644
>05468
Length = 1558
Score = 88.6 bits (218), Expect = 2e-18, Method: Compositional matrix adjust.
Identities = 61/197 (30%), Positives = 104/197 (52%), Gaps = 11/197 (5%)
Frame = -3
Query: 31 FKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGP-IKFNVWDTAGQ 89
+K++++G+ GTGKT+ +KR++ F + Y AT+GV+ V + + I+ +WD AGQ
Sbjct: 1538 YKILVIGELGTGKTSIIKRYVHQFFSQHYRATIGVDFALKVLNWDADTLIRLQLWDIAGQ 1359
Query: 90 EKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDL---VRVCEN--IPIVLCGNKV 144
E+FG + YY +A A ++FDVT T+ V W DL V++ + +P VL NK
Sbjct: 1358 ERFGNMTRVYYKEAVGAFVVFDVTRASTFDAVTKWKNDLDSKVQLADGSPVPCVLLANKC 1179
Query: 145 D-IKDRKVKAKSIV--FHRKKN-LQYYDISAKSNYNFEKPFLWLARKLIGDPNLEFVAMP 200
D K+ V S + F +K + +Y+ SAK N N ++ +L +++ +
Sbjct: 1178 DQAKEGLVNNTSQMDEFCSEKGFIGWYETSAKENINIDEAARFLVTRILEKDRAMQLGDD 999
Query: 201 ALAPPEVVMD-PALAAQ 216
+V+D P+ Q
Sbjct: 998 DRDRDRIVLDKPSSGTQ 948
>17511
Length = 483
Score = 87.0 bits (214), Expect = 6e-18, Method: Compositional matrix adjust.
Identities = 40/124 (32%), Positives = 72/124 (58%), Gaps = 5/124 (4%)
Frame = -3
Query: 28 QVQFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTA 87
+V K++++GD G GKT+ + +++ +F +Y AT+G + + + +WDTA
Sbjct: 373 KVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTA 194
Query: 88 GQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLV-----RVCENIPIVLCGN 142
GQE+F L +Y A C +++FDVT T++++ +W + + R EN P V+ GN
Sbjct: 193 GQERFQSLGVAFYRGADCCVLVFDVTMPNTFRSLDSWRDEFLIQASPRDPENFPFVVIGN 14
Query: 143 KVDI 146
K+D+
Sbjct: 13 KIDL 2
>33374
Length = 489
Score = 71.6 bits (174), Expect(2) = 2e-17, Method: Compositional matrix adjust.
Identities = 35/101 (34%), Positives = 61/101 (60%), Gaps = 3/101 (2%)
Frame = +1
Query: 79 IKFNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCE-NIPI 137
+KF +WDTAGQE++ L YY AQ AI+++D+T++ T+ W ++L R NI I
Sbjct: 175 VKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQDTFGRAKTWVKELQRQASPNIVI 354
Query: 138 VLCGNKVDIKDRKVK--AKSIVFHRKKNLQYYDISAKSNYN 176
L GNK D+ ++++ ++ + + +L + + SAK+ N
Sbjct: 355 ALAGNKADLANKRMVEFEEAQAYAEENSLLFMETSAKTAMN 477
Score = 34.3 bits (77), Expect(2) = 2e-17, Method: Compositional matrix adjust.
Identities = 18/43 (41%), Positives = 28/43 (65%)
Frame = +2
Query: 22 AAQGEPQVQFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLG 64
A QG+ QFKLVL+G+ GK++ V R + G+F + +T+G
Sbjct: 8 ATQGKI-CQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIG 133
>34468
Length = 1502
Score = 85.1 bits (209), Expect = 3e-17, Method: Compositional matrix adjust.
Identities = 54/193 (27%), Positives = 94/193 (48%), Gaps = 11/193 (5%)
Frame = +1
Query: 26 EPQVQ---FKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFN 82
E Q Q FK++++GD GKT R G+F K AT+GV+ + +K
Sbjct: 472 EKQTQRRIFKIIVIGDSNVGKTCLTYRFCLGKFPDKTEATIGVDFREKSIQVDSEHLKLQ 651
Query: 83 VWDTAGQEKF-GGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVR--VCENIPIVL 139
+WDTAGQE+F + YY + ++D+T +++N+P W + R + + IP +L
Sbjct: 652 LWDTAGQERFRKSMVQHYYRNVHAVVFVYDMTKMSSFENMPAWIEECDRHNLTKYIPRIL 831
Query: 140 CGNKVDIKDRKVKAKSIV--FHRKKNLQYYDISAKSNY---NFEKPFLWLARKLIGDPNL 194
GNK D+ +R ++ F N+ ++ SAK + + + F+ +A KL +
Sbjct: 832 VGNKCDVVERIAVNTNLAQKFADAHNMPLFETSAKDDEKANHVDAIFMTVAHKLKXSKPM 1011
Query: 195 EFVAMPALAPPEV 207
+ + P +V
Sbjct: 1012MPAHLSEMVPGDV 1050
>13901
Length = 962
Score = 83.2 bits (204), Expect = 8e-17, Method: Compositional matrix adjust.
Identities = 38/100 (38%), Positives = 60/100 (60%), Gaps = 1/100 (1%)
Frame = -3
Query: 26 EPQVQFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFH-TNRGPIKFNVW 84
+V FK++++GD GKT+FV+R++ F + Y T+GV+ V +++ IK +W
Sbjct: 300 SEEVLFKVIIIGDPTVGKTSFVQRYVNDSFRRDYKMTIGVDFALKVIRWSDKCNIKLQLW 121
Query: 85 DTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNW 124
D AGQE+F + YY A I+MFD+T + TY+N W
Sbjct: 120 DIAGQERFTSMTRVYYKDAHACIVMFDLTQKNTYQNAIRW 1
>26083
Length = 432
Score = 79.3 bits (194), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 39/129 (30%), Positives = 68/129 (52%), Gaps = 4/129 (3%)
Frame = +1
Query: 19 AAMAAQGE---PQVQFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTN 75
+ M + GE P +FKLV +G+ GKT+ + R + F+ Y AT+G++ +
Sbjct: 34 SIMTSSGEFGNPLRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLE 213
Query: 76 RGPIKFNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDL-VRVCEN 134
I+ +WDTAGQE+F L Y + A++++D+T+ ++ W D+ +
Sbjct: 214 DRTIRLQLWDTAGQERFRSLIPSYIRDSSVAVVVYDITNANSFHQTSKWIDDVRTERGSD 393
Query: 135 IPIVLCGNK 143
+ I+L GNK
Sbjct: 394 VIIMLVGNK 420
>11728
Length = 635
Score = 79.3 bits (194), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 41/121 (33%), Positives = 65/121 (53%), Gaps = 1/121 (0%)
Frame = -1
Query: 31 FKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQE 90
K V+VGDG GKT + + T F +Y+ T+ + + + PI +WDTAGQE
Sbjct: 488 IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTV-FDNYSANVMVDSKPINLGLWDTAGQE 312
Query: 91 KFGGLRDGYYIQAQCAIIMFDVTSRVTYKNV-PNWHRDLVRVCENIPIVLCGNKVDIKDR 149
+ LR Y Q +I F + S +++NV W+ ++ C N PI+L G K+D+++
Sbjct: 311 DYDRLRPLSYPQTDVFLICFSLISPASFENVKAKWYPEVSHHCPNTPIILVGTKLDLRED 132
Query: 150 K 150
K
Sbjct: 131 K 129
>07465
Length = 1103
Score = 79.3 bits (194), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 44/154 (28%), Positives = 78/154 (50%), Gaps = 4/154 (2%)
Frame = +3
Query: 44 TTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQEKFGGLRDGYYIQA 103
++ ++R+ G F K Y T+GV+ ++ +WDTAGQE+F + YY A
Sbjct: 240 SSMIQRYCKGIFTKDYKKTIGVDFLERQIEVGGEDVRLMLWDTAGQEEFDAITKAYYRGA 419
Query: 104 QCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLCGNKVDIKD----RKVKAKSIVFH 159
Q ++ F R +++ + W R + I +V+ NK+D+ D R +A+++
Sbjct: 420 QACVLAFSTVDRDSFEALETWKRKVEDEVGEIGMVIVQNKIDLIDDAVVRPEEAENLA-- 593
Query: 160 RKKNLQYYDISAKSNYNFEKPFLWLARKLIGDPN 193
+K L++Y S K N N ++ F +LA K + N
Sbjct: 594 KKLRLRFYRTSVKENMNVDEVFRYLADKYLHQLN 695
>19006
Length = 568
Score = 72.8 bits (177), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 39/118 (33%), Positives = 63/118 (53%), Gaps = 1/118 (0%)
Frame = -2
Query: 32 KLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQEK 91
KLV+VGDG GKT + +F + YV T+ E + + ++ +WDTAGQE
Sbjct: 432 KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTV-FENYVADIEVDSKQVELALWDTAGQED 256
Query: 92 FGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPN-WHRDLVRVCENIPIVLCGNKVDIKD 148
+ LR Y ++ F + S + +N+P W ++ C N+PI+L GNK D+++
Sbjct: 255 YDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVRHFCPNVPIILVGNKKDLRN 82
>11257
Length = 1102
Score = 72.4 bits (176), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 35/113 (30%), Positives = 64/113 (56%), Gaps = 7/113 (6%)
Frame = -2
Query: 83 VWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCE-----NIPI 137
+WDTAGQE++ LR +Y C ++ F V + + +++ +W+ + V + + P
Sbjct: 1014 IWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLKSLQSLSDWYDEFVNYADIQDSASFPF 835
Query: 138 VLCGNKVDIKDRKVKAKSIV--FHRKKNLQYYDISAKSNYNFEKPFLWLARKL 188
V+ GNK DI++R+V ++ NL Y++ SAK + N ++ FL + R+L
Sbjct: 834 VIIGNKADIEEREVSSEDAYNWCRTHGNLPYFETSAKDSLNVQQAFLAVVRRL 676
>07580
Length = 921
Score = 62.0 bits (149), Expect(2) = 1e-12, Method: Compositional matrix adjust.
Identities = 31/112 (27%), Positives = 62/112 (55%), Gaps = 4/112 (3%)
Frame = +3
Query: 81 FNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRV--CENIPIV 138
+ DTAG E+F +RD Y Q ++ + +T++ T+ ++ ++RV +++P++
Sbjct: 210 LEILDTAGTEQFTAMRDLYMKNGQGFLLAYSITAQSTFNDLQELREQILRVKDTDDVPML 389
Query: 139 LCGNKVDIKDRKV--KAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKL 188
L GNK D++D +V K + R + + + SAK+ N + F+ L R++
Sbjct: 390 LVGNKCDLEDERVVGKDQGQGLARSFSCAFLETSAKARINVNEIFMDLVRQI 545
Score = 27.3 bits (59), Expect(2) = 1e-12, Method: Compositional matrix adjust.
Identities = 11/30 (36%), Positives = 19/30 (63%)
Frame = +2
Query: 26 EPQVQFKLVLVGDGGTGKTTFVKRHLTGEF 55
E ++KLV++G GG GK+ + + G+F
Sbjct: 47 ETMREYKLVVLGSGGVGKSALTVQFVQGDF 136
>30760
Length = 596
Score = 66.2 bits (160), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 44/162 (27%), Positives = 78/162 (48%), Gaps = 8/162 (4%)
Frame = -1
Query: 32 KLVLVGDGGTGKTTFVK--RHLTGEFEKKYVATLGVEVHPLVFHT--NRGPIKFNVWDTA 87
K ++ GD G GK++ + + F K Y T GVEV + + +R ++ ++D+A
Sbjct: 524 KCIVTGDSGVGKSSICQVFHSDSAHFPKNYSMTTGVEVLVKLVNIPDSRDQVELYLFDSA 345
Query: 88 GQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCEN--IPIVLCGNKVD 145
G+E F ++ Q ++++DVT ++ W + N IP VL NK D
Sbjct: 344 GKEIFSENVTKFWDQPSVVMVVYDVTDETSFSGCVRWLERVRAAKPNTVIPGVLVANKTD 165
Query: 146 IKDRK--VKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLA 185
+ +R+ + + + L+Y++ SAK N + PF LA
Sbjct: 164 LDERRRVSRKEGKDLAQSHGLEYFECSAKEMQNTDTPFFCLA 39
>33794
Length = 779
Score = 63.9 bits (154), Expect = 6e-11, Method: Compositional matrix adjust.
Identities = 33/121 (27%), Positives = 65/121 (53%), Gaps = 2/121 (1%)
Frame = -1
Query: 79 IKFNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIV 138
+K +WDT+GQ +F + Y AQ I+++D+T++ ++ + W +++ IP V
Sbjct: 650 VKLQIWDTSGQGRFCTIIRSYSRGAQGIILVYDITNKWSFDGIDRWLKEVEEHAPGIPKV 471
Query: 139 LCGNKVDIK-DRKVKAKSI-VFHRKKNLQYYDISAKSNYNFEKPFLWLARKLIGDPNLEF 196
L GN++ + R+V AK + + N+ ++IS ++N + F LAR + +E
Sbjct: 470 LVGNRLHLAYKRQVAAKQAETYASRNNMSCFEISPLCDFNIRESFCELARMALHRNGMEH 291
Query: 197 V 197
+
Sbjct: 290 I 288
>13745
Length = 1045
Score = 63.2 bits (152), Expect = 8e-11, Method: Compositional matrix adjust.
Identities = 34/108 (31%), Positives = 59/108 (54%), Gaps = 7/108 (6%)
Frame = +2
Query: 89 QEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLV-----RVCENIPIVLCGNK 143
QE+F L +Y A C ++++DVT+ ++KN+ +W + + R E+ P V+ GNK
Sbjct: 2 QERFQSLGVAFYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPEHFPFVVLGNK 181
Query: 144 VDIKDRKVKAKSIV--FHRKKNLQYYDISAKSNYNFEKPFLWLARKLI 189
VD+ +R+V + K ++ YY+ SAK N E F +A+ +
Sbjct: 182 VDLDNRQVSTRRAQQWCQSKNDIPYYETSAKEGINVEMAFQTIAKNAL 325
>12339
Length = 578
Score = 61.6 bits (148), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 38/121 (31%), Positives = 63/121 (52%), Gaps = 8/121 (6%)
Frame = -2
Query: 89 QEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLV-----RVCENIPIVLCGNK 143
QE+F L +Y A C I+++DVT T+ ++ +W R+ + R E+ P V+ GNK
Sbjct: 577 QERFQSLGVAFYRGADCCILVYDVTEXKTFDSLDSWQREFLNQASPRDPEHFPFVVIGNK 398
Query: 144 VDIKDRKVKAK--SIVFHRKKNLQYYDISAKSNYNFEKPFLWLARK-LIGDPNLEFVAMP 200
+D+ +R V AK K + Y++ SAK N E+ F +A+ L + +E P
Sbjct: 397 IDLDNRVVTAKRGQGWCSTKGGIPYFETSAKEAINVEQAFQTVAKNALAQESEVEIDDFP 218
Query: 201 A 201
+
Sbjct: 217 S 215
>19656
Length = 428
Score = 58.9 bits (141), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 33/102 (32%), Positives = 51/102 (50%), Gaps = 1/102 (0%)
Frame = +3
Query: 32 KLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQEK 91
K V+VGDG GKT + + T F +Y+ T+ V R P+ +WDTAGQE
Sbjct: 117 KCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGR-PVNLGLWDTAGQED 293
Query: 92 FGGLRDGYYIQAQCAIIMFDVTSRVTYKNV-PNWHRDLVRVC 132
+ LR Y Q ++ F V S +++N+ W+ ++ C
Sbjct: 294 YDRLRPLSYPQTDVFLLCFSVASPASFENIRAKWYPEVNHHC 419
>33380
Length = 282
Score = 57.8 bits (138), Expect = 4e-09, Method: Compositional matrix adjust.
Identities = 29/82 (35%), Positives = 48/82 (58%), Gaps = 1/82 (1%)
Frame = +3
Query: 71 VFHTNRGPIKFNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDL-V 129
VF ++ +K +WDTAGQE++ + YY A I+M+DVT+ ++ V +W +
Sbjct: 39 VFRQDK-RVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDVTNEESFNAVQDWCTQIKT 215
Query: 130 RVCENIPIVLCGNKVDIKDRKV 151
+N +VL GNK D++D +V
Sbjct: 216 YSWDNAQVVLVGNKCDLEDERV 281
>35581
Length = 364
Score = 54.7 bits (130), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 28/88 (31%), Positives = 43/88 (48%), Gaps = 1/88 (1%)
Frame = +2
Query: 25 GEPQVQFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPI-KFNV 83
G + FK VL+GD G GKT + R T +F + +L G + ++
Sbjct: 29 GNDTLYFKCVLLGDAGVGKTCLLNRLATDKFLDSPLTSLTTASLLTTVTLTSGVMASVDL 208
Query: 84 WDTAGQEKFGGLRDGYYIQAQCAIIMFD 111
WDTAGQE++ L YY + +I++D
Sbjct: 209 WDTAGQERYRSLTSSYYRDTKAVLIVYD 292
>01398
Length = 1421
Score = 52.8 bits (125), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 34/103 (33%), Positives = 59/103 (57%), Gaps = 5/103 (4%)
Frame = -2
Query: 89 QEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWH---RDLVRVCENIPIVLCGNKVD 145
QE+F + YY + II++D+T R T++N+ W+ R+ + + I +VL G+K D
Sbjct: 1420 QERFRSITRSYYRNSVGVIIVYDITKRSTFENLKQWYEEARNHIEPHKAIFLVL-GHKSD 1244
Query: 146 IKD-RKVKAKS-IVFHRKKNLQYYDISAKSNYNFEKPFLWLAR 186
+D R+V A+ F L++++ SAKS +N E F +A+
Sbjct: 1243 REDARQVTAREGRRFAEMHGLKFFETSAKSGHNIEDVFAQIAK 1115
>32723
Length = 384
Score = 52.4 bits (124), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 31/105 (29%), Positives = 53/105 (50%), Gaps = 3/105 (2%)
Frame = +2
Query: 89 QEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNW-HRDLVRVCENIPIVLCGNKVDIK 147
QE+F + YY A I+++DV S+ +Y+++P W H + + L GNK+D
Sbjct: 2 QERFRSITQSYYRSANALILVYDVCSQQSYESLPQWIHEIELYAGTKVLAFLVGNKIDQT 181
Query: 148 DRKVKAKSI--VFHRKKNLQYYDISAKSNYNFEKPFLWLARKLIG 190
D++ I F + +++ + SAK N EK F +A +L
Sbjct: 182 DKREIPTHIGKEFAERYEMRFLETSAKEADNVEKLFSTIAYQLTA 316
>26536
Length = 829
Score = 52.0 bits (123), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 33/114 (28%), Positives = 56/114 (49%), Gaps = 4/114 (3%)
Frame = +2
Query: 79 IKFNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPI- 137
+ + DTAGQE++ +R+ Y I+++ VT +++ R L R + I
Sbjct: 128 VSWTFLDTAGQEEYSSMREHYTRSGDGFIVVYSVTDVTSFQEAEAVFRWLTRFQDETSIH 307
Query: 138 -VLCGNKVDI-KDRKVK-AKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKL 188
VLCGNK D+ DRKV + + + Y++ SAK+ N + + L R +
Sbjct: 308 AVLCGNKTDLTSDRKVTPEEGRKMADRLGMLYFETSAKTGDNVSQVYHGLLRSI 469
>31291
Length = 446
Score = 51.6 bits (122), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 31/117 (26%), Positives = 54/117 (46%), Gaps = 16/117 (13%)
Frame = -1
Query: 81 FNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVP-NWHRDLVRVCENIPIVL 139
+WDTAGQE + LR Y ++ F + S + KNV W+ ++ ++PIVL
Sbjct: 446 LQLWDTAGQEDYDRLRPLAYPNTDVFMLXFSLMSEASMKNVKVKWYPEIRHHDPHVPIVL 267
Query: 140 CGNKVDIKDRKVKAKSIVFHRK---------------KNLQYYDISAKSNYNFEKPF 181
G K+D++ K + + R+ K +Y++ S+K+ N + F
Sbjct: 266 VGTKLDLRQDKEAVRKLRSSRQDPVSSNQGNDLAKAIKAKRYFECSSKTQENLKTAF 96
>13750
Length = 503
Score = 51.2 bits (121), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 31/145 (21%), Positives = 71/145 (48%), Gaps = 6/145 (4%)
Frame = -2
Query: 43 KTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGP---IKFNVWDTAGQEKFGGLRDGY 99
KT ++R+ G F + + T+ V F+ +R +++ +WDT G E + L +
Sbjct: 502 KTCLLRRYQKGFFMDRTMPTIAVLCSE--FNESRTDPLNVRYTLWDTGGAETYRSLWVSH 329
Query: 100 YIQAQCAIIMFDVTSRVTYKNVPN-WHRDLVRVCENIPIVLCGNKVDIKDRKVKA--KSI 156
+ AQ A++++DVT ++ W + L++ ++ G+K D+++ +V + +
Sbjct: 328 FRGAQVALLVYDVTCEWSFLTATTVWRKALMKNIPEAQVIFVGSKTDLEENRVISTERGQ 149
Query: 157 VFHRKKNLQYYDISAKSNYNFEKPF 181
F + +++ S+ + N + F
Sbjct: 148 AFATQCGYTFFETSSVTGKNVDAVF 74
>27191
Length = 443
Score = 51.2 bits (121), Expect = 4e-07, Method: Compositional matrix adjust.
Identities = 26/103 (25%), Positives = 55/103 (53%), Gaps = 1/103 (0%)
Frame = +1
Query: 43 KTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQEKFGGLRDGYYIQ 102
KT +K +F + Y T+GV+ + N ++ ++WD +G ++ +R+ Y
Sbjct: 1 KTCLIKHFCESKFNQGYQPTVGVDYGFKIQTVNGVDMRVHMWDLSGSNEYLDVRNELYTG 180
Query: 103 AQCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPI-VLCGNKV 144
+ I+FDV++ +++ + +W R++ R P+ V+ GN+V
Sbjct: 181 SDAIFIVFDVSNTPSFEALDSWLREINRFATGSPLNVIVGNRV 309
>00858
Length = 1658
Score = 50.4 bits (119), Expect = 6e-07, Method: Compositional matrix adjust.
Identities = 30/115 (26%), Positives = 60/115 (52%), Gaps = 7/115 (6%)
Frame = -2
Query: 81 FNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRV--CENIPIV 138
++ DTAGQE+ +RD + + +F V + +++++ + + RV + +P+V
Sbjct: 1441 LDILDTAGQEEXSAMRDQCMRTGEGFLCVFAVXNLKSFEDINQYREQIKRVKDADEVPMV 1262
Query: 139 LCGNKVD-----IKDRKVKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKL 188
L GNKVD ++ R+ K + ++H + Y + SAK+ + F L R++
Sbjct: 1261 LVGNKVDLPIRNVEQRQGKHMAELYH----IPYVETSAKTRQGVDDAFYTLVREI 1109
>19046
Length = 445
Score = 49.7 bits (117), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 27/88 (30%), Positives = 51/88 (57%), Gaps = 4/88 (4%)
Frame = -2
Query: 89 QEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCE--NIPIVLCGNKVD- 145
QE+F +R+ Y + +++F VT +++N+ N+H ++RV + + P++LC NKVD
Sbjct: 444 QEEFSAMREQYMRKGDGFLLVFSVTDFRSFENMANFHTQILRVKDRDSYPMILCANKVDL 265
Query: 146 IKDRKVKAKSIV-FHRKKNLQYYDISAK 172
+ RKV + + + + Y + SAK
Sbjct: 264 VHQRKVSEEQVRDLATRLRIPYIETSAK 181
>29380
Length = 853
Score = 47.0 bits (110), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 32/93 (34%), Positives = 52/93 (55%), Gaps = 6/93 (6%)
Frame = -2
Query: 103 AQCAIIMFDVTSRVTYKNVPNWHRDLVRV-CENIPIVLCGNKVDI--KDRKVK---AKSI 156
A AII++DV T+ W ++L + E++ I+L GNKVD+ + R V A+S
Sbjct: 852 ASAAIIVYDVNIADTFSRALAWVKELRQQNTESVLIILAGNKVDLATQHRAVSFEDAQS- 676
Query: 157 VFHRKKNLQYYDISAKSNYNFEKPFLWLARKLI 189
F R+ L + ++SAK+ + F+ LA +LI
Sbjct: 675 -FARENGLLFAEVSAKTGMAVNEIFMTLANQLI 580
>24619
Length = 509
Score = 47.0 bits (110), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 30/109 (27%), Positives = 56/109 (51%), Gaps = 5/109 (4%)
Frame = -2
Query: 89 QEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCE--NIPIVLCGNKVD- 145
QE+F +R+ Y + +++F V +++N+ N+H ++RV + P++LC NKVD
Sbjct: 508 QEEFSAMREQYMRKGDGFLLVFSVIDYQSFENMVNFHTQILRVKDRDTYPMILCANKVDL 329
Query: 146 IKDRKVKAKSIV-FHRKKNLQYYDISAKS-NYNFEKPFLWLARKLIGDP 192
+ RKV + + + + Y + SAK N + F + R + P
Sbjct: 328 VHQRKVSEEQVRDLATRLRIPYIETSAKDPPLNVDLAFHQVVRVIRAQP 182
>00552
Length = 455
Score = 42.0 bits (97), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 19/65 (29%), Positives = 34/65 (52%)
Frame = -3
Query: 65 VEVHPLVFHTNRGPIKFNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNW 124
V P V+H +WDTAGQE++ LR +Y C ++ F V + + +++ +W
Sbjct: 180 VAASPDVWH-------HGIWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLKSLQSLSDW 22
Query: 125 HRDLV 129
+ + V
Sbjct: 21 YDEFV 7
Score = 37.4 bits (85), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 15/36 (41%), Positives = 26/36 (72%)
Frame = -1
Query: 31 FKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVE 66
K+VL+GDGG GK++ + R ++ +F+ + T+GVE
Sbjct: 443 LKVVLLGDGGVGKSSLMNRFVSNKFDAQSFHTIGVE 336
>36482
Length = 686
Score = 41.6 bits (96), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 32/111 (28%), Positives = 53/111 (47%), Gaps = 5/111 (4%)
Frame = +2
Query: 49 RHLTGEFEKKYVATLGVEVHPLVFHT--NRGPIKFNVWDTAGQEKFGGLRDGYYIQAQCA 106
R LT F +Y TL +HT ++ + DTAGQ + ++GY + A C
Sbjct: 11 RFLTRRFIGEYCPTLE---SVYKYHTVIEDDDVRLEILDTAGQGTYP-WKEGYALWADCF 178
Query: 107 IIMFDVTSRVTYKNVPNWHRDL--VRVCENIPIVLCGNKVD-IKDRKVKAK 154
+ ++ + R +Y+ + R + VR ++ VL NK D + DR+V K
Sbjct: 179 VFVYSINDRQSYEELVQVKRQVESVRKSTSLTAVLAANKTDLLHDRQVTQK 331
>08153
Length = 1703
Score = 39.7 bits (91), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 25/86 (29%), Positives = 39/86 (45%)
Frame = +1
Query: 30 QFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQ 89
+ ++++VG GKTT + + GE + T+G V + + I F VWD GQ
Sbjct: 82 EVRILMVGLDAAGKTTILYKLKLGEIVTT-IPTIGFNVETVEYKN----ISFTVWDVGGQ 246
Query: 90 EKFGGLRDGYYIQAQCAIIMFDVTSR 115
+K L Y+ Q I + D R
Sbjct: 247 DKIRPLWRHYFQNTQGLIFVVDSNDR 324
>14775
Length = 380
Score = 38.1 bits (87), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 21/74 (28%), Positives = 40/74 (54%), Gaps = 3/74 (4%)
Frame = -2
Query: 43 KTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGP---IKFNVWDTAGQEKFGGLRDGY 99
KT ++R+ G F + + T+ V F+ +R +++ +WDT G E + L +
Sbjct: 379 KTCLLRRYQKGFFMDRTMPTIAVLCSE--FNESRTDPLNVRYTLWDTGGAETYRSLWVSH 206
Query: 100 YIQAQCAIIMFDVT 113
+ AQ A++++DVT
Sbjct: 205 FRGAQVALLVYDVT 164
>09204
Length = 1051
Score = 37.0 bits (84), Expect = 0.007, Method: Compositional matrix adjust.
Identities = 24/101 (23%), Positives = 49/101 (48%), Gaps = 6/101 (5%)
Frame = -3
Query: 91 KFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLCGNKVDI---- 146
++ + YY A+ AI+ FD+T + ++ + W +L + E + +CG K D+
Sbjct: 1049 RYEAMSRIYYRGAKAAILCFDLTDKSSFDRIRFWIGELRQHEEECKLYICGTKFDLVHDD 870
Query: 147 KDRKVKAKSIVFHRKKNL--QYYDISAKSNYNFEKPFLWLA 185
+R+ +S+ + + Y+ S+ + N EK F +A
Sbjct: 869 PERRAVPRSVAKALADDCMAEIYETSSMTGDNIEKLFTKIA 747
>09827
Length = 1201
Score = 37.0 bits (84), Expect = 0.008, Method: Compositional matrix adjust.
Identities = 24/81 (29%), Positives = 37/81 (45%)
Frame = -3
Query: 31 FKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQE 90
++++VG GKTT + + GE + T+G V + + I F VWD GQ+
Sbjct: 1112 MRILMVGLDAAGKTTILYKLKLGEIVTT-IPTIGFNVETVEYKN----ISFTVWDVGGQD 948
Query: 91 KFGGLRDGYYIQAQCAIIMFD 111
K L Y+ Q I + D
Sbjct: 947 KIRPLWRHYFQNTQGLIFVVD 885
>33605
Length = 888
Score = 35.8 bits (81), Expect = 0.014, Method: Compositional matrix adjust.
Identities = 29/114 (25%), Positives = 47/114 (41%)
Frame = +1
Query: 3 CGAARALASVLCLRRNAAMAAQGEPQVQFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVAT 62
CG R L + + + + + +L+++G GKTT +K+ GE T
Sbjct: 418 CGG-RILLGDTAMGLLTILKKMKQKEKEVRLLMLGLDNAGKTTILKK-FNGEDIDTISPT 591
Query: 63 LGVEVHPLVFHTNRGPIKFNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRV 116
LG + L +RG K NVWD GQ+ Y+ + + D R+
Sbjct: 592 LGFNIKTL---EHRG-FKLNVWDVGGQQSLRSYWRNYFESTDGLVWVVDSADRM 741
>10708
Length = 2775
Score = 35.4 bits (80), Expect = 0.019, Method: Compositional matrix adjust.
Identities = 14/44 (31%), Positives = 24/44 (54%)
Frame = -2
Query: 79 IKFNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVP 122
++ +WDTAGQE + LR Y ++ F + S + +N+P
Sbjct: 2723 VELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIP 2592
Score = 30.4 bits (67), Expect = 0.62, Method: Compositional matrix adjust.
Identities = 14/48 (29%), Positives = 28/48 (58%)
Frame = -3
Query: 101 IQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLCGNKVDIKD 148
+ + CA + +T+ T ++ W ++ C N+PI+L GNK D+++
Sbjct: 2647 MSSLCASPLTALTAWRT--SLKKWTPEVRHFCPNVPIILVGNKKDLRN 2510
>20290
Length = 1550
Score = 33.1 bits (74), Expect = 0.11, Method: Compositional matrix adjust.
Identities = 19/46 (41%), Positives = 26/46 (56%), Gaps = 3/46 (6%)
Frame = +1
Query: 33 LVLVGDGGTGKTTFVKRHLTGEFE---KKYVATLGVEVHPLVFHTN 75
LVL+G+ GTGKTTF+ R L G + + + L + P FH N
Sbjct: 787 LVLLGENGTGKTTFI-RMLAGNLQPDGEVELPMLNISYKPQKFHRN 921
>10862
Length = 2896
Score = 32.3 bits (72), Expect = 0.15, Method: Compositional matrix adjust.
Identities = 15/36 (41%), Positives = 18/36 (50%)
Frame = -3
Query: 80 KFNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSR 115
+FNVWD GQ+K L YY Q I + D R
Sbjct: 2483 QFNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADR 2376
>13795
Length = 642
Score = 29.6 bits (65), Expect = 1.1, Method: Compositional matrix adjust.
Identities = 17/33 (51%), Positives = 20/33 (60%), Gaps = 1/33 (3%)
Frame = -1
Query: 21 MAAQGEPQVQFK-LVLVGDGGTGKTTFVKRHLT 52
M A E Q Q K L ++GDGGT T+FV LT
Sbjct: 204 MTAGSEVQAQAKRLQILGDGGTQPTSFVNSVLT 106
>18248
Length = 466
Score = 28.9 bits (63), Expect = 1.8, Method: Compositional matrix adjust.
Identities = 13/24 (54%), Positives = 19/24 (79%)
Frame = +3
Query: 33 LVLVGDGGTGKTTFVKRHLTGEFE 56
+V++G+ GTGKTTF+K L G+ E
Sbjct: 108 IVMLGENGTGKTTFIKM-LAGKLE 176
>33029
Length = 1133
Score = 28.9 bits (63), Expect = 1.9, Method: Compositional matrix adjust.
Identities = 11/30 (36%), Positives = 16/30 (53%)
Frame = +1
Query: 97 DGYYIQAQCAIIMFDVTSRVTYKNVPNWHR 126
D +I CAI M ++ ++KN P W R
Sbjct: 682 DCKFILGTCAIFMQQTDTKPSHKNTPQWAR 771
>11357
Length = 1307
Score = 27.3 bits (59), Expect = 4.8, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 27/42 (64%), Gaps = 4/42 (9%)
Frame = -2
Query: 165 QYYDISA---KSNYNFEKPFLWLA-RKLIGDPNLEFVAMPAL 202
++YD S+ K+NY+F+K F+W + +L +LE++ + L
Sbjct: 733 EHYDFSSCISKNNYSFKKGFIWFSCIQLFKRGSLEYMLVFVL 608
>02253
Length = 1110
Score = 27.3 bits (59), Expect = 6.2, Method: Compositional matrix adjust.
Identities = 18/61 (29%), Positives = 26/61 (42%), Gaps = 1/61 (1%)
Frame = +3
Query: 58 KYVATLG-VEVHPLVFHTNRGPIKFNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRV 116
+Y+A L + VH V + KFN+ DT+ + F +I C T RV
Sbjct: 213 EYLAQLDKLFVHQKVERNDLASTKFNIMDTSQKPAFEAAESSSFISRLCCFGFRGFTYRV 392
Query: 117 T 117
T
Sbjct: 393 T 395
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000378199 | hsapiens_gene_ensembl | Heat
shock-related 70 kDa protein 2 (Heat shock 70 kDa protein 2).
[Source:Uniprot/SWISSPROT;Acc:P54652]
(639 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
30255 280 e-104
21024 218 9e-57
27378 194 1e-49
26390 165 6e-41
37715 149 4e-36
24750 139 3e-33
06909 99 1e-24
31218 94 1e-19
09881 88 1e-17
20979 86 3e-17
12271 64 2e-10
13684 55 7e-08
03996 52 7e-07
34036 50 3e-06
13300 49 5e-06
>30255
Length = 1761
Score = 280 bits (717), Expect(2) = e-104, Method: Compositional matrix adjust.
Identities = 144/206 (69%), Positives = 156/206 (75%)
Frame = -1
Query: 331 KGQIQEIVLVGGSTRIPKIQKLLQDFFNGKELNKSINPDEXXXXXXXXXXXILIGDKSEN 390
K I EIVLVGGSTRIPKIQKLLQDFFNGKEL KSINPDE IL GDKSE
Sbjct: 1644 KPGIHEIVLVGGSTRIPKIQKLLQDFFNGKELCKSINPDEAVAYGACVQAAILHGDKSEE 1465
Query: 391 VQDXXXXXXXXXXXGIETAGGVMTPLIKRNXXXXXXXXXXXXXYSDNQSSVLVQVYEGER 450
VQD GIETAGGVMT LIKRN YSDNQ VL+QVYEGER
Sbjct: 1464 VQDLLLLDVAPLSMGIETAGGVMTALIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGER 1285
Query: 451 AMTKDNNLLGKFDLTGIPPAPRGVPQIEVTFDIDANGILNVTAADKSTGKENKITITNDK 510
AMT+DNNLLGKF+LTGIPPAPRGVPQIEVTFDIDANGILNV+AADKSTGKENKITITNDK
Sbjct: 1284 AMTRDNNLLGKFELTGIPPAPRGVPQIEVTFDIDANGILNVSAADKSTGKENKITITNDK 1105
Query: 511 GRLSKDDIDRMVQEAERYKSEDEANR 536
GRLSK++I+RMV +AE+ ++ + R
Sbjct: 1104 GRLSKEEIERMVNDAEKSRTMMTSRR 1027
Score = 117 bits (293), Expect(2) = e-104, Method: Compositional matrix adjust.
Identities = 52/79 (65%), Positives = 69/79 (87%)
Frame = -3
Query: 537 DRVAAKNALESYTYNIKQTVEDEKLRGKISEQDKNKILDKCQEVINWLDRNQMAEKDEYE 596
+R+++KN+LESY +++K T+EDEK++ KI E+DK I+DKC EVI+WLD NQ AEKDEY+
Sbjct: 1027 NRISSKNSLESYAFHMKSTIEDEKIKDKIGEEDKKTIVDKCNEVISWLDANQTAEKDEYD 848
Query: 597 HKQKELERVCNPIISKLYQ 615
KQKELE+VCNPII+KLYQ
Sbjct: 847 DKQKELEKVCNPIITKLYQ 791
>21024
Length = 3220
Score = 218 bits (554), Expect = 9e-57, Method: Compositional matrix adjust.
Identities = 127/331 (38%), Positives = 189/331 (57%), Gaps = 10/331 (3%)
Frame = +1
Query: 264 RRLRTAC------ERAKRTLSSSTQASIEIDSLYEGVD----FYTSITRARFEELNADLF 313
+R++ C +++K LSSS Q I + L ++R++FE L L
Sbjct: 988 QRIQWLCRDYVRQQKSKIELSSSLQTDINLPYLTMDASGPKHMNLKLSRSKFESLVESLV 1167
Query: 314 RGTLEPVEKALRDAKLDKGQIQEIVLVGGSTRIPKIQKLLQDFFNGKELNKSINPDEXXX 373
+ T+ P +KAL+DA++ K I E++LVGG +R+PK+Q +QD F G+ +KS+NPDE
Sbjct: 1168 KRTVGPCQKALQDAEVKKSDIGEVILVGGMSRMPKVQSTVQDLF-GRTPSKSVNPDEAVA 1344
Query: 374 XXXXXXXXILIGDKSENVQDXXXXXXXXXXXGIETAGGVMTPLIKRNXXXXXXXXXXXXX 433
+L GD V D GIET GGV T LI RN
Sbjct: 1345 IGAAIQGGVLAGD----VTDVLLLDVTPLSLGIETLGGVFTKLINRNTTIPTKKSQVFST 1512
Query: 434 YSDNQSSVLVQVYEGERAMTKDNNLLGKFDLTGIPPAPRGVPQIEVTFDIDANGILNVTA 493
+D Q+ V ++V++GER M DN LLG+F L GIPPAPRGVPQ+EVTFDIDANGI+NV+A
Sbjct: 1513 AADGQTQVEIKVHQGEREMANDNKLLGQFTLVGIPPAPRGVPQVEVTFDIDANGIVNVSA 1692
Query: 494 ADKSTGKENKITITNDKGRLSKDDIDRMVQEAERYKSEDEANRDRVAAKNALESYTYNIK 553
DK TGKE +I I + G LSKD+I+ M++ AE + +D ++ V N +S ++ +
Sbjct: 1693 RDKGTGKEQQIVIQSSGG-LSKDEIENMIKNAEAHAEDDRRKKELVEVLNQADSIIHDTE 1869
Query: 554 QTVEDEKLRGKISEQDKNKILDKCQEVINWL 584
+E+ + ++ +++ +K+ +K EV L
Sbjct: 1870 SKMEE--FKDQLPQEECDKLREKINEVKQLL 1956
Score = 184 bits (467), Expect = 1e-46, Method: Compositional matrix adjust.
Identities = 117/271 (43%), Positives = 163/271 (60%), Gaps = 2/271 (0%)
Frame = +3
Query: 4 RGPAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQVAM 62
+G IGIDLGTT SCV + + + +++ N +G+RTTPS +AFT D ER+ G AK Q
Sbjct: 243 KGHVIGIDLGTTNSCVALMEGKQAKVLENSEGSRTTPSVIAFTKDGERISGMPAKRQAVT 422
Query: 63 NPTNTIFDAKRLIGRKFEDATVQSDMKHWPFRVVSEGGKPKVQVEYKGETKTFFPEEISS 122
N NT+ KRLIGR+FED VQ DMK+ +++V + VE +G K + P ++ +
Sbjct: 423 NAENTLSATKRLIGRRFEDPEVQKDMKNVSYKIV-KASNGDAWVEAQG--KMYSPSQVGA 593
Query: 123 MVLTKMKEIAEAYLGGKVHSAVITVPAYFNDSQRQATKDAGTITGLNVLRIINEPTAAAI 182
VL KMKE AE+YLG KV++AV+TVPAYFNDSQRQATKDAG I+GL + ++ T +
Sbjct: 594 FVLMKMKETAESYLGSKVNNAVVTVPAYFNDSQRQATKDAGQISGLKCV-ACDQRTHSCS 770
Query: 183 AYGLDKKGCAGGEKNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGE-DFDNRMV 241
+ + LI G T +S + + + + T +TH E FDN MV
Sbjct: 771 SCFMAWTSLKIK**RCLI*AEGRLT-SLSWRSRRECLKSNQPT--ETHSWEERTFDNYMV 941
Query: 242 SHLAEEFKRKHKKDIGPNKRAVRRLRTACER 272
+ LA EFK++ DI + AV+RLR A E+
Sbjct: 942 NFLASEFKKEQGLDITKDPMAVQRLREAAEK 1034
>27378
Length = 410
Score = 194 bits (492), Expect = 1e-49, Method: Compositional matrix adjust.
Identities = 94/124 (75%), Positives = 106/124 (85%)
Frame = -1
Query: 247 EFKRKHKKDIGPNKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGVDFYTSITRARFE 306
EFKRK+KKD+ N RA+RRLRTA ERAKRTLSSST+A+IE+D+L+EG DFYT I+RARFE
Sbjct: 410 EFKRKYKKDLRSNPRALRRLRTAAERAKRTLSSSTEATIEVDALFEGHDFYTKISRARFE 231
Query: 307 ELNADLFRGTLEPVEKALRDAKLDKGQIQEIVLVGGSTRIPKIQKLLQDFFNGKELNKSI 366
EL ADLFR TL PVEKAL DAK+DK I +IVLVGGSTRIPK+Q LLQ FF GK LN SI
Sbjct: 230 ELCADLFRQTLAPVEKALNDAKMDKQMIHDIVLVGGSTRIPKVQNLLQQFFGGKSLNLSI 51
Query: 367 NPDE 370
NPDE
Sbjct: 50 NPDE 39
>26390
Length = 665
Score = 165 bits (417), Expect = 6e-41, Method: Compositional matrix adjust.
Identities = 87/183 (47%), Positives = 112/183 (61%), Gaps = 6/183 (3%)
Frame = +2
Query: 405 GIETAGGVMTPLIKRNXXXXXXXXXXXXXYSDNQSSVLVQVYEGERAMTKDNNLLGKFDL 464
GIET GGVMT LI R DNQ SV +QVYEGER+ TKDN+LLG+FDL
Sbjct: 50 GIETVGGVMTTLIARGTTIPARKAKVFSTAQDNQDSVTIQVYEGERSRTKDNHLLGRFDL 229
Query: 465 TGIPPAPRGVPQIEVTFDIDANGILNVTAADKSTGKENKITITNDKGRLSKDDIDRMVQE 524
TGIP APRGVPQIEVTF +DANG++ V+A DK TG++N I I LS +D++RMVQE
Sbjct: 230 TGIPAAPRGVPQIEVTFQVDANGVMQVSAEDKGTGQKNDIIIQQSGSGLSPEDVERMVQE 409
Query: 525 AERYKSEDEANRDRVAAKNALESYTYNIKQTVED------EKLRGKISEQDKNKILDKCQ 578
A+ + ED R+ ++ LES Y + ++D + G +S+ D L Q
Sbjct: 410 AQDFAEEDRKFRELTESRTGLESLAYTAQHQLQDLHKMXASERPGTLSDDD----LHXAQ 577
Query: 579 EVI 581
EV+
Sbjct: 578 EVV 586
>37715
Length = 468
Score = 149 bits (376), Expect = 4e-36, Method: Compositional matrix adjust.
Identities = 72/113 (63%), Positives = 86/113 (76%)
Frame = -2
Query: 93 FRVVSEGGKPKVQVEYKGETKTFFPEEISSMVLTKMKEIAEAYLGGKVHSAVITVPAYFN 152
+V+++ KP +Q G TKTF PEEIS+MVL KM++IAEAYLG K+ +AV+TVPAYFN
Sbjct: 458 LKVINKSNKPHIQALVSGATKTFAPEEISAMVLGKMRDIAEAYLGKKIDNAVVTVPAYFN 279
Query: 153 DSQRQATKDAGTITGLNVLRIINEPTAAAIAYGLDKKGCAGGEKNVLIFDLGG 205
D+QRQATKDAGTI GLNV+RIINEPTAAAIAYGLDK+ GEK
Sbjct: 278 DAQRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKR---DGEKTFWCLTWAA 129
Score = 81.3 bits (199), Expect = 1e-15, Method: Composition-based stats.
Identities = 34/49 (69%), Positives = 44/49 (89%)
Frame = -1
Query: 196 KNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVSHL 244
+N+L+FDLGGGTFDVS+LTI++G+FEV +T GDTHLGGEDFD R++ H
Sbjct: 159 ENILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMDHF 13
>24750
Length = 552
Score = 139 bits (351), Expect = 3e-33, Method: Compositional matrix adjust.
Identities = 65/71 (91%), Positives = 71/71 (100%)
Frame = +1
Query: 442 LVQVYEGERAMTKDNNLLGKFDLTGIPPAPRGVPQIEVTFDIDANGILNVTAADKSTGKE 501
++QVYEGERAMT+DNNLLGKF+LTGIPPAPRGVPQIEVTFDIDANGILNV+AADKSTGKE
Sbjct: 154 MLQVYEGERAMTRDNNLLGKFELTGIPPAPRGVPQIEVTFDIDANGILNVSAADKSTGKE 333
Query: 502 NKITITNDKGR 512
NKITITNDKG+
Sbjct: 334 NKITITNDKGQ 366
>06909
Length = 456
Score = 99.4 bits (246), Expect(2) = 1e-24, Method: Compositional matrix adjust.
Identities = 45/65 (69%), Positives = 56/65 (86%)
Frame = -3
Query: 551 NIKQTVEDEKLRGKISEQDKNKILDKCQEVINWLDRNQMAEKDEYEHKQKELERVCNPII 610
++K T+EDEK++ KIS +DK ILDKC EVI WLD NQ+AEKDEY+ KQKE+E+VCNPII
Sbjct: 385 HMKSTIEDEKIKDKISTEDKKTILDKCDEVIAWLDANQLAEKDEYDDKQKEIEKVCNPII 206
Query: 611 SKLYQ 615
+KLYQ
Sbjct: 205 TKLYQ 191
Score = 32.7 bits (73), Expect(2) = 1e-24, Method: Composition-based stats.
Identities = 12/22 (54%), Positives = 18/22 (81%)
Frame = -1
Query: 527 RYKSEDEANRDRVAAKNALESY 548
+YK +DE + R++AKN+LESY
Sbjct: 456 KYKEDDEKQKSRISAKNSLESY 391
>31218
Length = 322
Score = 94.4 bits (233), Expect = 1e-19, Method: Compositional matrix adjust.
Identities = 48/100 (48%), Positives = 68/100 (68%)
Frame = +2
Query: 228 DTHLGGEDFDNRMVSHLAEEFKRKHKKDIGPNKRAVRRLRTACERAKRTLSSSTQASIEI 287
DTHLGGEDFD R+V +L + K+K +D+ + RA+ RLR + E+AKR LSS +++
Sbjct: 2 DTHLGGEDFDQRLVDYLVKLIKQKTGRDVRHDTRAMSRLRRSAEKAKRALSSQHSTKVDL 181
Query: 288 DSLYEGVDFYTSITRARFEELNADLFRGTLEPVEKALRDA 327
D + + T +TRA+FEELN DLFR TL V++AL D+
Sbjct: 182 DGVTSDLADLT-LTRAKFEELNTDLFRSTLTTVKRALEDS 298
>09881
Length = 600
Score = 87.8 bits (216), Expect = 1e-17, Method: Composition-based stats.
Identities = 41/106 (38%), Positives = 64/106 (60%)
Frame = +3
Query: 7 AIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTN 66
A G+ LGT +C+ V++ GK + AND G+R+TP VAFT + +G +AK + N N
Sbjct: 186 AYGVHLGTCSACLAVYKDGKTSVAANDAGDRSTPCVVAFTACDAEVGASAKQGIVSNVKN 365
Query: 67 TIFDAKRLIGRKFEDATVQSDMKHWPFRVVSEGGKPKVQVEYKGET 112
T+ + KR++G FED Q + P +VV++ +P +VE+K T
Sbjct: 366 TVCNVKRILGLTFEDPVTQEYLASSPVKVVNQKNQPMFEVEFKERT 503
Score = 45.8 bits (107), Expect = 5e-05, Method: Composition-based stats.
Identities = 24/50 (48%), Positives = 32/50 (64%)
Frame = +2
Query: 137 GGKVHSAVITVPAYFNDSQRQATKDAGTITGLNVLRIINEPTAAAIAYGL 186
G + AV+ VP+ F+D QR A A + G VLR+INE +AAA+AY L
Sbjct: 2 GKGIQDAVLAVPSDFSDKQRAAASAAASKAGFKVLRLINECSAAALAYDL 151
>20979
Length = 976
Score = 86.3 bits (212), Expect = 3e-17, Method: Compositional matrix adjust.
Identities = 48/140 (34%), Positives = 81/140 (57%), Gaps = 2/140 (1%)
Frame = +1
Query: 233 GEDFDNRMVSHLAEEF--KRKHKKDIGPNKRAVRRLRTACERAKRTLSSSTQASIEIDSL 290
G + R+ HLA+ F ++K + N RA+ +L ER K+ LS+++ +++ L
Sbjct: 70 GVEMTLRLRDHLAKVFNGQKKRSFKLEDNPRAMAKLLKEAERVKKVLSANSDHKAQVEGL 249
Query: 291 YEGVDFYTSITRARFEELNADLFRGTLEPVEKALRDAKLDKGQIQEIVLVGGSTRIPKIQ 350
EG DF ++R + EL DL +P+E AL+ +++ +I EI+L+GG +R+P++Q
Sbjct: 250 VEGEDFAAKVSREDYLELIKDLLARVTKPMEDALKVSEITMPEITEIILMGGGSRVPRVQ 429
Query: 351 KLLQDFFNGKELNKSINPDE 370
+ L F +L KSIN DE
Sbjct: 430 EELLKFSGKSDLGKSINTDE 489
>12271
Length = 1762
Score = 63.9 bits (154), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 30/76 (39%), Positives = 47/76 (61%)
Frame = +2
Query: 295 DFYTSITRARFEELNADLFRGTLEPVEKALRDAKLDKGQIQEIVLVGGSTRIPKIQKLLQ 354
DF +TR ++ L DL PV++ L +++ +I EI+L+GG +R+PKI ++L
Sbjct: 41 DFSCKVTRDKYLHLIQDLLDRVTLPVQQVLTASQITWAEITEIILMGGGSRLPKIHEILL 220
Query: 355 DFFNGKELNKSINPDE 370
D+ KEL KS+N DE
Sbjct: 221 DYSGKKELGKSLNTDE 268
Score = 32.7 bits (73), Expect = 0.43, Method: Compositional matrix adjust.
Identities = 23/98 (23%), Positives = 44/98 (44%), Gaps = 3/98 (3%)
Frame = +1
Query: 490 NVTAADKSTGKENKITIT---NDKGRLSKDDIDRMVQEAERYKSEDEANRDRVAAKNALE 546
N AA G K+ +T D LSKD + + + ++ DE A+N +E
Sbjct: 937 NKKAASAGKGFNEKLKVTVKVKDMAELSKDQVKQSKKRLTDWRKRDEEKAAVQKARNEVE 1116
Query: 547 SYTYNIKQTVEDEKLRGKISEQDKNKILDKCQEVINWL 584
S+ + + +E +++++ ILD+ + +WL
Sbjct: 1117 SFIITAQDKMSEETYLASSTDEERAXILDQLSQASDWL 1230
>13684
Length = 438
Score = 55.5 bits (132), Expect = 7e-08, Method: Composition-based stats.
Identities = 24/57 (42%), Positives = 36/57 (63%)
Frame = -3
Query: 7 AIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMN 63
A G+ LGT +C+ V++ GK + AND G+R+TP VAFT + +G +AK + N
Sbjct: 172 AYGVHLGTCSACLAVYKDGKTSVAANDAGDRSTPCVVAFTACDAEVGASAKQGIVSN 2
>03996
Length = 1105
Score = 52.0 bits (123), Expect = 7e-07, Method: Compositional matrix adjust.
Identities = 26/64 (40%), Positives = 41/64 (64%)
Frame = -2
Query: 307 ELNADLFRGTLEPVEKALRDAKLDKGQIQEIVLVGGSTRIPKIQKLLQDFFNGKELNKSI 366
EL DL +P+E AL+ +++ +I EI+L+GG +R+P++Q+ L F +L KSI
Sbjct: 1056 ELIKDLLARVTKPMEDALKVSEITMPEITEIILMGGGSRVPRVQEELLKFSGKSDLGKSI 877
Query: 367 NPDE 370
N DE
Sbjct: 876 NTDE 865
>34036
Length = 363
Score = 50.1 bits (118), Expect = 3e-06, Method: Composition-based stats.
Identities = 20/25 (80%), Positives = 24/25 (96%)
Frame = +2
Query: 591 EKDEYEHKQKELERVCNPIISKLYQ 615
EKDEY+ KQKE+E+VCNPII+KLYQ
Sbjct: 2 EKDEYDDKQKEIEKVCNPIITKLYQ 76
>13300
Length = 453
Score = 49.3 bits (116), Expect = 5e-06, Method: Compositional matrix adjust.
Identities = 35/149 (23%), Positives = 73/149 (48%), Gaps = 15/149 (10%)
Frame = +3
Query: 155 QRQATKDAGTITGLNVLRIINEPTAAAIAYGL-DKKGCAGGEKNVLIFDLGGGTFDVSIL 213
+R+A A G+NVL+++ + A A+ YG+ +K + + +D+G + +++
Sbjct: 3 ERRAIMTAADXVGINVLQLMTDSAAVALNYGVFRRKNFNTTAQYYMFYDMGATSTVATVV 182
Query: 214 T-----IEDGI-------FEVKSTAGDTHLGGEDFDNRMVSHLAEEFKRKHKKD--IGPN 259
+ +++G +K D LGG + R+ HLA+ F + K+ + N
Sbjct: 183 SYQVVKVKEGTRVESNPQLTIKGVGFDRTLGGLEMTLRLRDHLAKVFNGQKKRSFKLEDN 362
Query: 260 KRAVRRLRTACERAKRTLSSSTQASIEID 288
RA+ +L ER K+ LS+++ +++
Sbjct: 363 PRAMAKLLKEAERVKKVLSANSDHKAQVE 449
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000342944 | hsapiens_gene_ensembl | TOP2A_HUMAN
Isoform 2 of P11388 - Homo sapiens (Human)
[Source:Uniprot/Varsplic;Acc:P11388-2]
(1554 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
35806 219 e-103
09028 300 4e-81
19642 253 4e-67
19997 159 8e-39
>35806
Length = 792
Score = 219 bits (557), Expect(2) = e-103, Method: Compositional matrix adjust.
Identities = 100/133 (75%), Positives = 117/133 (87%)
Frame = +3
Query: 507 FPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKNYEDEDSLKTLRYGKIMIMTDQD 566
FPLRGK+LNVREA+HKQIM+NAEINNIIKI+GL +K+ Y+ D L+TLRYG++MIMTDQD
Sbjct: 3 FPLRGKLLNVREATHKQIMDNAEINNIIKILGLHFKEKYDSSDKLRTLRYGRLMIMTDQD 182
Query: 567 QDGSHIKGLLINFIHHNWPSLLRHRFLEEFITPIVKVSKNKQEMAFYSLPEFEEWKSSTP 626
QDGSHIKGLLINFIHH WP+LL+ F+EEFITPIVKV+K K E +F+SLPEFEEWK +T
Sbjct: 183 QDGSHIKGLLINFIHHFWPNLLQQNFVEEFITPIVKVTKGKAEHSFFSLPEFEEWKRNTD 362
Query: 627 NHKKWKVKYYKGL 639
N WKVKYYKGL
Sbjct: 363 NWHTWKVKYYKGL 401
Score = 176 bits (447), Expect(2) = e-103, Method: Compositional matrix adjust.
Identities = 82/122 (67%), Positives = 100/122 (81%)
Frame = +2
Query: 639 LGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAISLAFSKKQIDDRKEWLTNFMEDRRQR 698
GTSTSKEAKEYF+DM RHRI F+Y G EDDA+I+LAFSKK+I++RKEWLTN+ME+R++R
Sbjct: 398 FGTSTSKEAKEYFSDMPRHRIPFRYGGSEDDASINLAFSKKKIEERKEWLTNYMEERKRR 577
Query: 699 KLLGLPEDXXXXXXXXXXXXNDFINKELILFSNSDNERSIPSMVDGLKPGQRKVLFTCFK 758
+GLPE N+FIN+ELILFSN+DN RSIPS++DGLKPGQRKV+FTC K
Sbjct: 578 TEMGLPELYLYTRDTRNITYNEFINRELILFSNADNVRSIPSLMDGLKPGQRKVIFTCIK 757
Query: 759 RN 760
RN
Sbjct: 758 RN 763
>09028
Length = 966
Score = 300 bits (767), Expect = 4e-81, Method: Compositional matrix adjust.
Identities = 159/298 (53%), Positives = 205/298 (68%), Gaps = 6/298 (2%)
Frame = -2
Query: 955 TQTYKEQVLEPMLNGTEKTPPLITDYREYHTDTTVKFVVKMTEEKLAEAERVGLHKVFKL 1014
TQ YKE+VLE ML GT+KTPP+ITDY+EYHTDTTVKFVVKMT EKLA+AE+ GLHK FKL
Sbjct: 965 TQNYKEEVLENMLQGTDKTPPMITDYKEYHTDTTVKFVVKMTPEKLAQAEQTGLHKTFKL 786
Query: 1015 QTSLTCNSMVLFDHVGCLKKYDTVLDILRDFFELRLKYYGLRKEWLLGMLGAESAKLNNQ 1074
Q++L+ N +VLFD+ GC+KKY V DI+R+FFE+RL Y RK ++ GML AES+KL+N
Sbjct: 785 QSNLSSN-LVLFDNRGCIKKYSCVADIMREFFEVRLDMYQRRKRYMEGMLTAESSKLDNI 609
Query: 1075 ARFILEKIDGKIIIENKPKKELIKVLIQRGYDSDPVKAWKEAQQKVPXXXXXXXXXXXXX 1134
ARFILEKI+GK+ IENK K+E+I++L+++GYDSDPVKAWKE Q K
Sbjct: 608 ARFILEKIEGKVTIENKAKREIIQMLVRKGYDSDPVKAWKETQAKDKDEPEDDDDNASTA 429
Query: 1135 XXXXXXVTDSGPTFNYLLDMPLWYLTKEKKDELCRLRNEKEQELDTLKRKSPSDLWKEDL 1194
T GP FNY+L++PLW LTKE+K+EL + + K +EL L+RK+PSDLW++DL
Sbjct: 428 SD-----TTGGPDFNYILNLPLWSLTKERKEELMKQGDSKREELFELRRKTPSDLWEDDL 264
Query: 1195 ATFIEELEAVEAKEKQDEQVXXXXXXX------XXXXXXTQMAEVLPSPRGQRVIPRI 1246
F+ L VE +EK D + + +PS G+RV PRI
Sbjct: 263 EQFMIMLNEVEEQEKADVSGXGAAVKMGKLGKVGKVKSKKAVVDTMPSIMGRRVEPRI 90
>19642
Length = 484
Score = 253 bits (646), Expect = 4e-67, Method: Compositional matrix adjust.
Identities = 114/159 (71%), Positives = 138/159 (86%)
Frame = -3
Query: 786 SLMMTIINLAQNFVGSNNLNLLQPIGQFGTRLHGGKDSASPRYIFTMLSSLARLLFPPKD 845
SLM TIINLAQNFVGSNNLNLLQP+GQFGTRLHGGKD+ASPRYIFTMLS LAR + KD
Sbjct: 479 SLMSTIINLAQNFVGSNNLNLLQPLGQFGTRLHGGKDAASPRYIFTMLSPLARHIVNSKD 300
Query: 846 DHTLKFLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWSCKIPNFDVREIVNNIRRLMDG 905
D L+ LYDDNQR+EPEWY PI+PMVL+NG +GIGTGWS +IPN DVRE+V N++RL++G
Sbjct: 299 DSLLRHLYDDNQRIEPEWYCPILPMVLVNGTDGIGTGWSTRIPNHDVREVVANLKRLING 120
Query: 906 EEPLPMLPSYKNFKGTIEELAPNQYVISGEVAILNSTTI 944
EPLPM+P++K F+G+IEEL N+YV SGEVA+++ T+
Sbjct: 119 LEPLPMIPAFKGFRGSIEELGENKYVCSGEVAVIDDDTV 3
>19997
Length = 522
Score = 159 bits (402), Expect = 8e-39, Method: Compositional matrix adjust.
Identities = 76/111 (68%), Positives = 92/111 (82%), Gaps = 2/111 (1%)
Frame = -1
Query: 21 EDAKKRLSVERIY-QKKTQLEHILLRPDTYIGSVELVTQQMWVYDEDVG-INYREVTFVP 78
+ A+K+ S+ + +K+QLEHILLRPDTYIGSVE VTQQMWV D++ + +RE+TFVP
Sbjct: 333 DQARKQTSISGAHLPEKSQLEHILLRPDTYIGSVESVTQQMWVMDDETNKMEFREITFVP 154
Query: 79 GLYKIFDEILVNAADNKQRDPKMSCIRVTIDPENNLISIWNNGKGIPVVEH 129
GLYKIFDEI+VNAADNK RDPKM ++V IDPENN + IWNNGKGIPVVEH
Sbjct: 153 GLYKIFDEIIVNAADNKVRDPKMDTLKVDIDPENNKVKIWNNGKGIPVVEH 1
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000350217 | hsapiens_gene_ensembl | TOP2A_HUMAN
Isoform 2 of P11388 - Homo sapiens (Human)
[Source:Uniprot/Varsplic;Acc:P11388-2]
(1568 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
35806 219 e-103
09028 300 3e-81
19642 253 4e-67
19997 159 9e-39
>35806
Length = 792
Score = 219 bits (558), Expect(2) = e-103, Method: Compositional matrix adjust.
Identities = 100/133 (75%), Positives = 117/133 (87%)
Frame = +3
Query: 520 FPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKNYEDEDSLKTLRYGKIMIMTDQD 579
FPLRGK+LNVREA+HKQIM+NAEINNIIKI+GL +K+ Y+ D L+TLRYG++MIMTDQD
Sbjct: 3 FPLRGKLLNVREATHKQIMDNAEINNIIKILGLHFKEKYDSSDKLRTLRYGRLMIMTDQD 182
Query: 580 QDGSHIKGLLINFIHHNWPSLLRHRFLEEFITPIVKVSKNKQEMAFYSLPEFEEWKSSTP 639
QDGSHIKGLLINFIHH WP+LL+ F+EEFITPIVKV+K K E +F+SLPEFEEWK +T
Sbjct: 183 QDGSHIKGLLINFIHHFWPNLLQQNFVEEFITPIVKVTKGKAEHSFFSLPEFEEWKRNTD 362
Query: 640 NHKKWKVKYYKGL 652
N WKVKYYKGL
Sbjct: 363 NWHTWKVKYYKGL 401
Score = 176 bits (447), Expect(2) = e-103, Method: Compositional matrix adjust.
Identities = 82/122 (67%), Positives = 100/122 (81%)
Frame = +2
Query: 652 LGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAISLAFSKKQIDDRKEWLTNFMEDRRQR 711
GTSTSKEAKEYF+DM RHRI F+Y G EDDA+I+LAFSKK+I++RKEWLTN+ME+R++R
Sbjct: 398 FGTSTSKEAKEYFSDMPRHRIPFRYGGSEDDASINLAFSKKKIEERKEWLTNYMEERKRR 577
Query: 712 KLLGLPEDXXXXXXXXXXXXNDFINKELILFSNSDNERSIPSMVDGLKPGQRKVLFTCFK 771
+GLPE N+FIN+ELILFSN+DN RSIPS++DGLKPGQRKV+FTC K
Sbjct: 578 TEMGLPELYLYTRDTRNITYNEFINRELILFSNADNVRSIPSLMDGLKPGQRKVIFTCIK 757
Query: 772 RN 773
RN
Sbjct: 758 RN 763
>09028
Length = 966
Score = 300 bits (768), Expect = 3e-81, Method: Compositional matrix adjust.
Identities = 159/298 (53%), Positives = 205/298 (68%), Gaps = 6/298 (2%)
Frame = -2
Query: 968 TQTYKEQVLEPMLNGTEKTPPLITDYREYHTDTTVKFVVKMTEEKLAEAERVGLHKVFKL 1027
TQ YKE+VLE ML GT+KTPP+ITDY+EYHTDTTVKFVVKMT EKLA+AE+ GLHK FKL
Sbjct: 965 TQNYKEEVLENMLQGTDKTPPMITDYKEYHTDTTVKFVVKMTPEKLAQAEQTGLHKTFKL 786
Query: 1028 QTSLTCNSMVLFDHVGCLKKYDTVLDILRDFFELRLKYYGLRKEWLLGMLGAESAKLNNQ 1087
Q++L+ N +VLFD+ GC+KKY V DI+R+FFE+RL Y RK ++ GML AES+KL+N
Sbjct: 785 QSNLSSN-LVLFDNRGCIKKYSCVADIMREFFEVRLDMYQRRKRYMEGMLTAESSKLDNI 609
Query: 1088 ARFILEKIDGKIIIENKPKKELIKVLIQRGYDSDPVKAWKEAQQKVPXXXXXXXXXXXXX 1147
ARFILEKI+GK+ IENK K+E+I++L+++GYDSDPVKAWKE Q K
Sbjct: 608 ARFILEKIEGKVTIENKAKREIIQMLVRKGYDSDPVKAWKETQAKDKDEPEDDDDNASTA 429
Query: 1148 XXXXXXVTDSGPTFNYLLDMPLWYLTKEKKDELCRLRNEKEQELDTLKRKSPSDLWKEDL 1207
T GP FNY+L++PLW LTKE+K+EL + + K +EL L+RK+PSDLW++DL
Sbjct: 428 SD-----TTGGPDFNYILNLPLWSLTKERKEELMKQGDSKREELFELRRKTPSDLWEDDL 264
Query: 1208 ATFIEELEAVEAKEKQDEQVXXXXXXX------XXXXXXTQMAEVLPSPRGQRVIPRI 1259
F+ L VE +EK D + + +PS G+RV PRI
Sbjct: 263 EQFMIMLNEVEEQEKADVSGXGAAVKMGKLGKVGKVKSKKAVVDTMPSIMGRRVEPRI 90
>19642
Length = 484
Score = 253 bits (647), Expect = 4e-67, Method: Compositional matrix adjust.
Identities = 114/159 (71%), Positives = 138/159 (86%)
Frame = -3
Query: 799 SLMMTIINLAQNFVGSNNLNLLQPIGQFGTRLHGGKDSASPRYIFTMLSSLARLLFPPKD 858
SLM TIINLAQNFVGSNNLNLLQP+GQFGTRLHGGKD+ASPRYIFTMLS LAR + KD
Sbjct: 479 SLMSTIINLAQNFVGSNNLNLLQPLGQFGTRLHGGKDAASPRYIFTMLSPLARHIVNSKD 300
Query: 859 DHTLKFLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWSCKIPNFDVREIVNNIRRLMDG 918
D L+ LYDDNQR+EPEWY PI+PMVL+NG +GIGTGWS +IPN DVRE+V N++RL++G
Sbjct: 299 DSLLRHLYDDNQRIEPEWYCPILPMVLVNGTDGIGTGWSTRIPNHDVREVVANLKRLING 120
Query: 919 EEPLPMLPSYKNFKGTIEELAPNQYVISGEVAILNSTTI 957
EPLPM+P++K F+G+IEEL N+YV SGEVA+++ T+
Sbjct: 119 LEPLPMIPAFKGFRGSIEELGENKYVCSGEVAVIDDDTV 3
>19997
Length = 522
Score = 159 bits (402), Expect = 9e-39, Method: Compositional matrix adjust.
Identities = 76/111 (68%), Positives = 92/111 (82%), Gaps = 2/111 (1%)
Frame = -1
Query: 22 EDAKKRLSVERIY-QKKTQLEHILLRPDTYIGSVELVTQQMWVYDEDVG-INYREVTFVP 79
+ A+K+ S+ + +K+QLEHILLRPDTYIGSVE VTQQMWV D++ + +RE+TFVP
Sbjct: 333 DQARKQTSISGAHLPEKSQLEHILLRPDTYIGSVESVTQQMWVMDDETNKMEFREITFVP 154
Query: 80 GLYKIFDEILVNAADNKQRDPKMSCIRVTIDPENNLISIWNNGKGIPVVEH 130
GLYKIFDEI+VNAADNK RDPKM ++V IDPENN + IWNNGKGIPVVEH
Sbjct: 153 GLYKIFDEIIVNAADNKVRDPKMDTLKVDIDPENNKVKIWNNGKGIPVVEH 1
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000262506 | hsapiens_gene_ensembl | Casein kinase
II subunit alpha' (EC 2.7.11.1) (CK II).
[Source:Uniprot/SWISSPROT;Acc:P19784]
(350 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
03508 368 e-102
00638 131 2e-43
01060 114 8e-26
12704 107 9e-24
14126 103 1e-22
04138 97 8e-21
01707 94 5e-20
04591 94 7e-20
29581 92 3e-19
32000 90 2e-18
01756 83 1e-16
21079 73 2e-13
15910 72 3e-13
26560 70 1e-12
23319 69 2e-12
01392 67 2e-11
12786 65 4e-11
01966 64 9e-11
00300 64 1e-10
12721 62 3e-10
31885 60 2e-09
30755 60 2e-09
14420 59 3e-09
03294 59 4e-09
18287 58 5e-09
13212 58 7e-09
19761 57 1e-08
26711 57 2e-08
27405 57 2e-08
18921 56 3e-08
09606 55 3e-08
28638 54 7e-08
13592 54 9e-08
03240 54 1e-07
18484 54 1e-07
19094 53 2e-07
21433 52 3e-07
18401 50 1e-06
07940 46 3e-05
13078 45 4e-05
37602 45 5e-05
31489 44 1e-04
13066 43 2e-04
11185 42 3e-04
01718 42 3e-04
05084 42 3e-04
26009 42 4e-04
17975 42 5e-04
00715 41 9e-04
00392 40 0.001
12453 38 0.007
14116 37 0.009
32359 28 0.010
27546 37 0.010
06358 37 0.014
01106 36 0.019
18481 36 0.019
02638 36 0.021
21800 35 0.030
28157 35 0.037
20773 33 0.13
15931 33 0.19
26909 33 0.21
19301 33 0.24
35032 33 0.24
18663 31 0.90
14104 30 1.1
29590 30 1.1
37063 30 1.1
12974 29 2.6
17644 29 2.9
36481 29 3.1
29360 29 3.5
21210 28 6.4
37603 28 6.6
12045 28 8.0
20152 27 8.7
>03508
Length = 1463
Score = 368 bits (944), Expect = e-102, Method: Compositional matrix adjust.
Identities = 172/234 (73%), Positives = 192/234 (82%)
Frame = +1
Query: 1 MPGPAAGSRARVYAEVNSLRSREYWDYEAHVPSWGNQDDYQLVRKLGRGKYSEVFEAINI 60
MP P SRARVYA+VN+ ++REYWDYE+HV WGNQDDYQ+VRKLGRGKYSEVFEAIN+
Sbjct: 487 MPLP---SRARVYADVNTHKAREYWDYESHVVEWGNQDDYQIVRKLGRGKYSEVFEAINV 657
Query: 61 TNNEXXXXXXXXXXXXXXXXXXXXXXXNLRGGTNIIKLIDTVKDPVSKTPALVFEYINNT 120
TNNE NLRGGTN+I L+ VKDPVS+TPAL+FE++NNT
Sbjct: 658 TNNEKCVIKILKPVKKKKIKREIKILENLRGGTNVITLLAIVKDPVSRTPALIFEHVNNT 837
Query: 121 DFKQLYQILTDFDIRFYMYELLKALDYCHSKGIMHRDVKPHNVMIDHQQKKLRLIDWGLA 180
DFKQLYQ TD+DIRFY+YEL+KALD+CHS GIMHRDVKPHNVMIDH+ KKLRLIDWGLA
Sbjct: 838 DFKQLYQTFTDYDIRFYLYELMKALDFCHSMGIMHRDVKPHNVMIDHENKKLRLIDWGLA 1017
Query: 181 EFYHPAQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRREPFF 234
EFYHP EYNVRVASRYFKGPELL+DYQMYDYSLDMWSLGCM ASMIFR+EP
Sbjct: 1018EFYHPGMEYNVRVASRYFKGPELLLDYQMYDYSLDMWSLGCMFASMIFRKEPLL 1179
Score = 176 bits (447), Expect = 1e-44, Method: Compositional matrix adjust.
Identities = 81/115 (70%), Positives = 96/115 (83%), Gaps = 3/115 (2%)
Frame = +2
Query: 217 WSLGCMLASM---IFRREPFFHGQDNYDQLVRIAKVLGTEELYGYLKKYHIDLDPHFNDI 273
W+ G A + + PFFHG DNYDQLVRIAKVLGT++LYGY++KY IDLDP FNDI
Sbjct: 1118 WTCGVWAACLPA*SSGKSPFFHGHDNYDQLVRIAKVLGTDDLYGYIEKYQIDLDPRFNDI 1297
Query: 274 LGQHSRKRWENFIHSENRHLVSPEALDLLDKLLRYDHQQRLTAKEAMEHPYFYPV 328
LG+HSRKRWE F+HSEN+HL+SPEALD LDKLLRYDH +RLTA+EAM+HPYF P+
Sbjct: 1298 LGRHSRKRWERFVHSENQHLISPEALDFLDKLLRYDHNERLTAREAMDHPYFXPI 1462
>00638
Length = 1595
Score = 131 bits (330), Expect(2) = 2e-43, Method: Compositional matrix adjust.
Identities = 57/79 (72%), Positives = 70/79 (88%)
Frame = +2
Query: 88 NLRGGTNIIKLIDTVKDPVSKTPALVFEYINNTDFKQLYQILTDFDIRFYMYELLKALDY 147
NLRGGTN+I L+ VKDPVS+TPAL+FE++NNTDFKQLYQ TD+DIRFY+YEL+KALD+
Sbjct: 284 NLRGGTNVITLLAIVKDPVSRTPALIFEHVNNTDFKQLYQTFTDYDIRFYLYELMKALDF 463
Query: 148 CHSKGIMHRDVKPHNVMID 166
CHS GIMHRDVKP +++
Sbjct: 464 CHSMGIMHRDVKPSPPLVN 520
Score = 62.4 bits (150), Expect(2) = 2e-43, Method: Compositional matrix adjust.
Identities = 29/37 (78%), Positives = 32/37 (86%)
Frame = +1
Query: 28 EAHVPSWGNQDDYQLVRKLGRGKYSEVFEAINITNNE 64
E + S NQDDYQ+VRKLGRGKYSEVFEAIN+TNNE
Sbjct: 103 EVRLLSRRNQDDYQIVRKLGRGKYSEVFEAINVTNNE 213
>01060
Length = 1800
Score = 114 bits (284), Expect = 8e-26, Method: Compositional matrix adjust.
Identities = 71/245 (28%), Positives = 129/245 (52%), Gaps = 9/245 (3%)
Frame = +1
Query: 93 TNIIKLIDTVKDPVSKTPALVFEYINNTDFKQLYQ------ILTDFDIRFYMYELLKALD 146
TNI+ L D + + + LVFE+++ D K +L ++ Y+++++ +
Sbjct: 250 TNIVCLEDVIME--DERLFLVFEFLS-MDLKMYIDKFPEGVVLDRRLVKSYVFQIVTGIX 420
Query: 147 YCHSKGIMHRDVKPHNVMIDHQQKKLRLIDWGLAE-FYHPAQEYNVRVASRYFKGPELLV 205
+CH + I+HRD+KP N++I+H +++ D+G+A F P + Y V + +++ PE+L+
Sbjct: 421 FCHQRRIVHRDLKPQNLLINH-TGAIKIADFGMARTFALPVRAYTHEVVTLWYRAPEILM 597
Query: 206 DYQMYDYSLDMWSLGCMLASMIFRREPFFHGQDNYDQLVRIAKVLG--TEELYGYLKKYH 263
Y +D+WS+G + A M+ R P F G DQL +I +++G TE+ + K
Sbjct: 598 GASKYSTPVDVWSIGTIFADMLI-RTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKL- 771
Query: 264 IDLDPHFNDILGQHSRKRWENFIHSENRHLVSPEALDLLDKLLRYDHQQRLTAKEAMEHP 323
P FN + W+ SE + LDL+++ L+ D QR++ K+ ++H
Sbjct: 772 ----PAFNGMF-----PLWKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHA 924
Query: 324 YFYPV 328
YF V
Sbjct: 925 YFLNV 939
>12704
Length = 641
Score = 107 bits (266), Expect = 9e-24, Method: Compositional matrix adjust.
Identities = 51/64 (79%), Positives = 56/64 (87%)
Frame = +3
Query: 1 MPGPAAGSRARVYAEVNSLRSREYWDYEAHVPSWGNQDDYQLVRKLGRGKYSEVFEAINI 60
MP P SRARVYA+VN+ + REYWDYE+HV WGNQDDYQ+VRKLGRGKYSEVFEAINI
Sbjct: 429 MPLP---SRARVYADVNTHKPREYWDYESHVVEWGNQDDYQIVRKLGRGKYSEVFEAINI 599
Query: 61 TNNE 64
TNNE
Sbjct: 600 TNNE 611
>14126
Length = 1265
Score = 103 bits (257), Expect = 1e-22, Method: Compositional matrix adjust.
Identities = 68/239 (28%), Positives = 122/239 (51%), Gaps = 7/239 (2%)
Frame = +3
Query: 94 NIIKLIDTVKDPVSKTPA---LVFEYINNTDFKQLYQI----LTDFDIRFYMYELLKALD 146
N+++L+D + ++ LVFEYI + L + L I+ M +LL +D
Sbjct: 381 NVVRLLDVSHNTITDREIRLNLVFEYIEHDLATYLAKCPSPGLGPDRIKDLMLQLLNGVD 560
Query: 147 YCHSKGIMHRDVKPHNVMIDHQQKKLRLIDWGLAEFYHPAQEYNVRVASRYFKGPELLVD 206
+ HS I+HRD+KP N++I + +L+L D+GLA Y V + +++ PE+L+
Sbjct: 561 FLHSNRIVHRDLKPQNLLIS-KDGRLKLADFGLARIYSFHMALTTVVVTLWYRSPEVLMQ 737
Query: 207 YQMYDYSLDMWSLGCMLASMIFRREPFFHGQDNYDQLVRIAKVLGTEELYGYLKKYHIDL 266
+ Y S+D+WS GC+ A + F R F G +DQL +I +V+G + + +
Sbjct: 738 AE-YGTSVDIWSCGCIFAEL-FTRRALFKGSSEFDQLKKIFEVIGLPPAGDWPEGVSV-- 905
Query: 267 DPHFNDILGQHSRKRWENFIHSENRHLVSPEALDLLDKLLRYDHQQRLTAKEAMEHPYF 325
H N + + + P+A DL++K+L + +R++++E++ HPY
Sbjct: 906 --HRNSFRPTPPVP-LQTLVPE-----MDPQAKDLMEKMLVFKSGRRISSRESLLHPYL 1058
>04138
Length = 800
Score = 97.4 bits (241), Expect = 8e-21, Method: Compositional matrix adjust.
Identities = 63/196 (32%), Positives = 104/196 (53%), Gaps = 7/196 (3%)
Frame = +1
Query: 145 LDYCHSKGIMHRDVKPHNVMIDHQQKKLRLIDWGLAEFY----HPAQEYNVRVASRYFKG 200
L Y H I+HRD+K N++I +Q L+L D+GLA + Y RV + +++
Sbjct: 52 LYYIHRNKILHRDMKAANILIT-KQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRP 228
Query: 201 PELLVDYQMYDYSLDMWSLGCMLASMIFRREPFFHGQDNYDQLVRIAKVLG--TEELYGY 258
PELL+ + Y ++D W GC++A M + R P G +QL I ++ G T E++
Sbjct: 229 PELLLGDRNYSTAIDQWGAGCIMAEM-WTRNPIMQGTTEQNQLTLITQLCGSITPEVWPG 405
Query: 259 LKKYHIDLDPHFNDILGQHSRKRWENFIHSE-NRHLVSPEALDLLDKLLRYDHQQRLTAK 317
+ + + ++ I G + R +N I R L P LDL ++LL+ D QR++A
Sbjct: 406 VTQLSM-----YHQIKGALAAGR-KNIIRDRFARILKDPYGLDLFERLLKMDPSQRISAD 567
Query: 318 EAMEHPYFYPVVKEQS 333
EA+ H +F+ V+ +S
Sbjct: 568 EALNHDFFWVGVEPKS 615
>01707
Length = 757
Score = 94.4 bits (233), Expect = 5e-20, Method: Compositional matrix adjust.
Identities = 54/162 (33%), Positives = 96/162 (59%), Gaps = 4/162 (2%)
Frame = +1
Query: 94 NIIKLIDTVKDPVSKTPALVFEYINNTDFKQLYQI---LTDFDIRFYMYELLKALDYCHS 150
N+++LI+ + K LVF+Y+++T +L + L + ++ +Y+ L A+++CH
Sbjct: 244 NLVRLIEVFRR--KKRLHLVFDYVDHTLLNELDRYPRGLPEPMVKRIIYQTLLAVNFCHQ 417
Query: 151 KGIMHRDVKPHNVMIDHQQKKLRLIDWGLAEFYH-PAQEYNVRVASRYFKGPELLVDYQM 209
+HRDVKP N++I +Q +++L D+G A P EY VA+R+++ PELLV
Sbjct: 418 YNTIHRDVKPENILIT-RQGQVKLCDFGFARILTGPGDEYTDYVATRWYRAPELLVGDTQ 594
Query: 210 YDYSLDMWSLGCMLASMIFRREPFFHGQDNYDQLVRIAKVLG 251
Y +D+W++GC+ A ++ + + G+ + DQL I K LG
Sbjct: 595 YGPPVDVWAIGCVFAELL-TGQALWPGRSDVDQLHLIRKTLG 717
>04591
Length = 1117
Score = 94.0 bits (232), Expect = 7e-20, Method: Compositional matrix adjust.
Identities = 67/229 (29%), Positives = 109/229 (47%), Gaps = 14/229 (6%)
Frame = -2
Query: 112 LVFEYINNTDFKQLYQILTDF---DIRFYMYELLKALDYCHSKGIMHRDVKPHNVMIDHQ 168
L+FEY + L + F D + M +LL L Y H+K I+HRD+K N+++ +
Sbjct: 966 LIFEYCDYDLAGLLNNLRVKFSLADKKNLMSQLLNGLFYIHTKQILHRDIKAANILLT-R 790
Query: 169 QKKLRLIDWGLAEFYHPAQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIF 228
L+L D+GL+ + ++ RV + +++ PELL+ + Y +DMW +GC++A M +
Sbjct: 789 DGVLKLADFGLSRPWVKSKRLTNRVVTLWYRPPELLLGEREYGPEIDMWGVGCIMAEM-W 613
Query: 229 RREPFFHGQDNYDQLVRIAKVLGT-----------EELYGYLKKYHIDLDPHFNDILGQH 277
R+P G+ QL I + G+ ELYG L D+
Sbjct: 612 SRKPLMQGRSEQHQLSLITDLCGSLNAEVWPGVTKLELYGKL------------DLPQGK 469
Query: 278 SRKRWENFIHSENRHLVSPEALDLLDKLLRYDHQQRLTAKEAMEHPYFY 326
RK E + L + E +L+D LR D QR+ A+ H +F+
Sbjct: 468 PRKVKERMLDL----LKNKEGAELIDIFLRLDPGQRMNCDNALSHDFFW 334
>29581
Length = 1278
Score = 92.0 bits (227), Expect = 3e-19, Method: Compositional matrix adjust.
Identities = 74/257 (28%), Positives = 127/257 (49%), Gaps = 8/257 (3%)
Frame = -2
Query: 88 NLRGGTNIIKLIDTVKDPVSKTPALVFEYINNTDFKQLYQILTDFD---IRFYMYELLKA 144
NLR NI++L + V + LV EY L + F ++ + +LLK
Sbjct: 1187 NLRH-QNIVQLQEVVVGKSLDSLFLVMEYCEQDLASLLDNMPAPFSESQVKCIVLQLLKG 1011
Query: 145 LDYCHSKGIMHRDVKPHNVMIDHQQKKLRLIDWGLAEFY-HPAQEYNVRVASRYFKGPEL 203
L Y H I+HRD+K N+++ + +++ D+GLA Y P + +V + +++ PEL
Sbjct: 1010 LRYLHEAFIIHRDLKVSNLLMT-DKGCVKIADFGLARNYGKPQKPMTPKVVTLWYRAPEL 834
Query: 204 LVDYQMYDYSLDMWSLGCMLASMIFRREPFFHGQDNYDQLVRIAKVLGTEELYGYLKKYH 263
L + + ++DMWS GC+L ++ + P G+ + Q+ I ++LGT +
Sbjct: 833 LFGSKTHSTAIDMWSAGCILGELLGHK-PLMPGRSDLQQIELIMELLGTP---------N 684
Query: 264 IDLDPHFNDI--LGQHSRKR--WENFIHSENRHLVSPEALDLLDKLLRYDHQQRLTAKEA 319
+ P F+ + Q + K+ + N H+ +S + LL+ L Y Q+R TA++
Sbjct: 683 DTIWPGFSQLPAFEQFTLKKQPYNNLRHT--FPWLSESGIRLLNGLFMYHPQKRATAEDC 510
Query: 320 MEHPYFYPVVKEQSQPC 336
+EH YF KEQ PC
Sbjct: 509 LEHSYF----KEQPYPC 471
>32000
Length = 644
Score = 89.7 bits (221), Expect = 2e-18, Method: Compositional matrix adjust.
Identities = 52/158 (32%), Positives = 84/158 (53%), Gaps = 3/158 (1%)
Frame = -1
Query: 171 KLRLIDWGLAE-FYHPAQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFR 229
K+++ D+GLA F P + Y V + +++ PE+L+ + Y +D+WSLGC+ M+ R
Sbjct: 575 KMKIADFGLARVFGLPVRTYTHEVITLWYRAPEILLGCRFYSVPVDIWSLGCIFVEMMTR 396
Query: 230 REPFFHGQDNYDQLVRIAKVLGT--EELYGYLKKYHIDLDPHFNDILGQHSRKRWENFIH 287
R F G DQL RI + LGT E+++ + K P + + K E +
Sbjct: 395 RA-LFPGDSEIDQLYRIFRTLGTPDEKVWPGVSKL-----PDYKPTFPKWPLKNLETVVS 234
Query: 288 SENRHLVSPEALDLLDKLLRYDHQQRLTAKEAMEHPYF 325
+S LDLL ++L Y+ +R++A+ AM HPYF
Sbjct: 233 ------LSKVGLDLLKRMLTYNPNRRISARSAMRHPYF 138
>01756
Length = 1858
Score = 83.2 bits (204), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 69/270 (25%), Positives = 116/270 (42%), Gaps = 18/270 (6%)
Frame = -3
Query: 1 MPGPAAGSRARVYAEVNSLRSREYWDYEAHVPSWGNQD-DYQLVRKLGRGKYSEVFEAIN 59
M A+ SR R + S+ Y YE + ++D Y+ + K+G+G + EVF+A
Sbjct: 1841 MSSTASASREREQKD-----SQRYSPYETLKFPFCDEDAKYEKLAKIGQGTFGEVFKARC 1677
Query: 60 ITNNEXXXXXXXXXXXXXX----XXXXXXXXXNLRGGTNIIKLIDTVKDPVSKTPA---- 111
+ L N++ LI+ +
Sbjct: 1676 KKTKQVVAMKKVLMDNEKEGFPITALREIKILQLLNHENVVDLIEICSTKATSANRYKSM 1497
Query: 112 --LVFEYINNTDFKQLYQILTDF---DIRFYMYELLKALDYCHSKGIMHRDVKPHNVMID 166
LVFE+ + L + F +I+ M +L+ L Y H I+HRD+K N++I
Sbjct: 1496 FYLVFEFCEHDLAGLLSNMSVVFNLPEIKEVMKQLMNGLYYIHRNKILHRDMKAANILIT 1317
Query: 167 HQQKKLRLIDWGLAEFY----HPAQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCM 222
+Q L+L D+GLA + Y RV + +++ PELL+ + Y ++D W GC+
Sbjct: 1316 -KQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRPPELLLGDRNYSTAIDQWGAGCI 1140
Query: 223 LASMIFRREPFFHGQDNYDQLVRIAKVLGT 252
+A M + R P G +QL I ++ G+
Sbjct: 1139 MAEM-WTRNPIMQGTTEQNQLTLITQLCGS 1053
>21079
Length = 878
Score = 72.8 bits (177), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 40/143 (27%), Positives = 79/143 (55%), Gaps = 5/143 (3%)
Frame = +1
Query: 95 IIKLIDTVKDPVSKTPALVFEYINNTD-FKQLYQ---ILTDFDIRFYMYELLKALDYCHS 150
++ L D + P +T LV E++ + F+++ + +LT+ D ++ ++ + Y H+
Sbjct: 10 LLMLWDAFEAP--RTMVLVMEFVGAGELFERVIRDDFVLTERDCVHFVRQICSGVGYMHT 183
Query: 151 KGIMHRDVKPHNVM-IDHQQKKLRLIDWGLAEFYHPAQEYNVRVASRYFKGPELLVDYQM 209
+ I+H D+KP NV+ + ++++ID+GLA FY P V + F PE +V+Y
Sbjct: 184 QSILHLDLKPENVLCVSDNSNQIKIIDFGLARFYKPGDSLQVLFGTPEFIAPE-VVNYDE 360
Query: 210 YDYSLDMWSLGCMLASMIFRREP 232
+++ DMWS+G + ++ P
Sbjct: 361 INFTTDMWSIGVICYILLSGLSP 429
>15910
Length = 1361
Score = 72.4 bits (176), Expect = 3e-13, Method: Compositional matrix adjust.
Identities = 53/207 (25%), Positives = 94/207 (45%), Gaps = 2/207 (0%)
Frame = +2
Query: 130 TDFDIRFYMYELLKALDYCHSKGIMHRDVKPHNVMIDHQQ--KKLRLIDWGLAEFYHPAQ 187
T+ D + ++L + Y H+ G++HRD+KP N++ + KL+L D+GL+ P
Sbjct: 458 TEKDAARAISDILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLADFGLSRIIEPEV 637
Query: 188 EYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRREPFFHGQDNYDQLVRIA 247
+ + + + PE+L + Y S+DMWS+G + ++ EPFF ++ +
Sbjct: 638 QMSTVCGTPGYCAPEVLKGDK-YTPSVDMWSVGVIAYILLCGYEPFF-AENEF------- 790
Query: 248 KVLGTEELYGYLKKYHIDLDPHFNDILGQHSRKRWENFIHSENRHLVSPEALDLLDKLLR 307
E+Y + K D + W +S A D++ KLL
Sbjct: 791 ------EMYRKIIKGEYKFDEEY-----------WSE---------ISENAKDVVRKLLV 892
Query: 308 YDHQQRLTAKEAMEHPYFYPVVKEQSQ 334
D ++RLTA EA+ P+ V + +
Sbjct: 893 IDPKKRLTATEALRLPWVKGVATKTTN 973
>26560
Length = 398
Score = 70.5 bits (171), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 35/108 (32%), Positives = 65/108 (60%)
Frame = -1
Query: 126 YQILTDFDIRFYMYELLKALDYCHSKGIMHRDVKPHNVMIDHQQKKLRLIDWGLAEFYHP 185
+ + T+ ++RFY E++ L++ HS+ +++RD+KP N+++D + +R+ D GLA +
Sbjct: 374 HGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLD-ENGHVRISDLGLACDFSK 198
Query: 186 AQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRREPF 233
+ + V + + PE+L+ Q YD S D +S GCML ++ PF
Sbjct: 197 KRPH-ASVGTHGYMAPEVLMKGQSYDSSADWFSFGCMLYKLLKGHSPF 57
>23319
Length = 2235
Score = 69.3 bits (168), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 42/127 (33%), Positives = 62/127 (48%), Gaps = 3/127 (2%)
Frame = +3
Query: 208 QMYDYSLDMWSLGCMLASMIFRREPFFHGQDNYDQLVRIAKVLGTEELYGYLKKYHIDLD 267
+MY S+DMWS GC+ A + P F G D+ DQL RI K+LGT + +
Sbjct: 21 KMYSTSIDMWSAGCIFAELANAGRPLFPGNDDDDQLKRIFKLLGTPTEDQWPGMTQL--- 191
Query: 268 PHFNDILGQHSRKRWENFIHSENRHLVSPEALDLLDKLLRYDHQQRLTAKEAMEHPYFY- 326
P++ H W+ + N + DLL LL R++A EA++HPYF
Sbjct: 192 PNYRMFPMYHVTTTWQQVVPKLNS-----KGRDLLQCLLVCCPSDRMSADEALQHPYFAD 356
Query: 327 --PVVKE 331
P+V++
Sbjct: 357 LPPLVRQ 377
>01392
Length = 1806
Score = 66.6 bits (161), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 58/221 (26%), Positives = 96/221 (43%), Gaps = 14/221 (6%)
Frame = -1
Query: 129 LTDFDIRFYMYELLKALDYCHSKGIMHRDVKPHNVMIDHQQK--KLRLIDWGLAEFYH-- 184
L + + + + +ALD+ HSKGI HRD+KP N++ +H +++ D+ LA
Sbjct: 1800 LCEREASLVVRHIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGISCD 1621
Query: 185 ----PAQEYNVRVASRYFKGPEL----LVDYQMYDYSLDMWSLGCMLASMIFRREPFFHG 236
E V S + PE+ + D YD D+WSLG +L M+ PF+ G
Sbjct: 1620 GDGTKTPELLTPVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILYIMLCGYPPFY-G 1444
Query: 237 QDNYDQLVRIAKVLGTEELYGYLKKYHIDLDPHFNDILGQHSRKRWENFIHSENRHLVSP 296
Q G + + + H D FN I H + S+ +S
Sbjct: 1443 Q------------CGEDCGWNRGEACHDCQDMLFNSIQDGHYK------FPSQEWTSISS 1318
Query: 297 EALDLLDKLLRYDHQQRLTAKEAMEHPYFY--PVVKEQSQP 335
A DL+ LL + ++R +A + ++HP+ P + + P
Sbjct: 1317 SAKDLIRHLLVREPRKRYSAADVLKHPWICTPPAATQLATP 1195
>12786
Length = 460
Score = 65.1 bits (157), Expect = 4e-11, Method: Compositional matrix adjust.
Identities = 42/136 (30%), Positives = 71/136 (52%), Gaps = 22/136 (16%)
Frame = -3
Query: 134 IRFYMYELLKALDYCHSKGIMHRDVKPHNVMIDHQQKKLRLIDWGLAEFYHPAQEY---N 190
I+FY E+L+A+ H++G++H D+KP N M+ L+LID+G+A + +
Sbjct: 404 IKFYWREMLRAVKALHNEGVIHSDLKPANFML--VAGNLKLIDFGIANTLQQDKTSVLKD 231
Query: 191 VRVASRYFKGPELLV-------DYQMYD--------YSL----DMWSLGCMLASMIFRRE 231
RV + + PE ++ D M + Y + D+WSLGC+L +M++ R
Sbjct: 230 SRVGTPSYMSPEAIMAACDDSADDSMEEDGHRTKPKYKVGVRSDVWSLGCILYNMVYGRT 51
Query: 232 PFFHGQDNYDQLVRIA 247
PF H ++N +L I
Sbjct: 50 PFQHIKNNMGKLQAIT 3
>01966
Length = 1735
Score = 63.9 bits (154), Expect = 9e-11, Method: Compositional matrix adjust.
Identities = 37/137 (27%), Positives = 76/137 (55%), Gaps = 7/137 (5%)
Frame = -1
Query: 93 TNIIKLIDTVKDPVSKTPALVFEYINNTDFKQLYQ------ILTDFDIRFYMYELLKALD 146
TNI+ L D + + + LVFE+++ D K +L ++ Y+++++ ++
Sbjct: 1534 TNIVCLEDVIME--DERLFLVFEFLS-MDLKMYIDKFPEGVVLDRRLVKSYVFQIVTGIN 1364
Query: 147 YCHSKGIMHRDVKPHNVMIDHQQKKLRLIDWGLAE-FYHPAQEYNVRVASRYFKGPELLV 205
+CH + I+HRD+KP N++I+H +++ D+G+A F P + Y V + +++ PE+L+
Sbjct: 1363 FCHQRRIVHRDLKPQNLLINH-TGAIKIADFGMARTFALPVRAYTHEVVTLWYRAPEILM 1187
Query: 206 DYQMYDYSLDMWSLGCM 222
Q + W+ G +
Sbjct: 1186 GPQ---STPPXWTCGAL 1145
Score = 60.5 bits (145), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 35/119 (29%), Positives = 60/119 (50%)
Frame = -3
Query: 210 YDYSLDMWSLGCMLASMIFRREPFFHGQDNYDQLVRIAKVLGTEELYGYLKKYHIDLDPH 269
Y +D+WS+G + A M+ R P F G DQL +I +++GT + + + + P
Sbjct: 1175 YSTPVDVWSIGTIFADMLIRT-PIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKL---PA 1008
Query: 270 FNDILGQHSRKRWENFIHSENRHLVSPEALDLLDKLLRYDHQQRLTAKEAMEHPYFYPV 328
FN + W+ SE + LDL+++ L+ D QR++ K+ ++H YF V
Sbjct: 1007 FNGMF-----PLWKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYFLNV 846
>00300
Length = 2318
Score = 63.5 bits (153), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 51/226 (22%), Positives = 102/226 (45%), Gaps = 18/226 (7%)
Frame = -1
Query: 40 YQLVRKLGRGKYSEVFEAINITNNEXXXXXXXXXXXXXXXXXXXXXXXNLRGGTNIIKLI 99
+Q K+G G++ +V+ A+N++ E LR + IK+
Sbjct: 1652 WQRGNKIGEGQFGKVYTAVNMSTGELMALKEMKFQPNDLQ--------QLREMCDEIKIF 1497
Query: 100 DTVKDP---------VSKTPALVF-EYINNTDFKQLYQI-LTDFDIRFYMYELLKALDYC 148
+ ++ V K L+F EY + ++ ++ L ++ IR Y E++ A+++
Sbjct: 1496 EGIQHENLVKYYGVEVHKDEMLMFMEYCDTGTIEEAAKMGLPEYLIRRYTREIVLAVNHL 1317
Query: 149 HSKGIMHRDVKPHNVMIDHQQKKLRLIDWGL-----AEFYHPAQEYNVRVASRYFKGPEL 203
H I+HRD+K N+ + ++L D+G + P + +N+ V + + PE+
Sbjct: 1316 HENSIVHRDIKGANIFLT-SNGHVKLGDFGCSVKLKSHTTMPGEFHNL-VGTTAYMAPEV 1143
Query: 204 LV--DYQMYDYSLDMWSLGCMLASMIFRREPFFHGQDNYDQLVRIA 247
D Y + D+WSLGC++ M + P+ +NY + ++
Sbjct: 1142 FTQNDQGGYGRAADIWSLGCVVIEMATGKRPWHDLDNNYQIMYKVG 1005
>12721
Length = 821
Score = 62.4 bits (150), Expect = 3e-10, Method: Compositional matrix adjust.
Identities = 33/95 (34%), Positives = 55/95 (57%), Gaps = 1/95 (1%)
Frame = +1
Query: 142 LKALDYCHSKGIMHRDVKPHNVMIDHQQKKLRLIDWGL-AEFYHPAQEYNVRVASRYFKG 200
LKAL + H+ G++HRD+K ++++ H K++L D+G A+ Q+ V + Y+
Sbjct: 403 LKALAFLHANGVIHRDIKSDSILLSH-DGKVKLXDFGFCAQVTQDLQKRKSLVGTPYWMA 579
Query: 201 PELLVDYQMYDYSLDMWSLGCMLASMIFRREPFFH 235
PE++ Y +D+WSLG M+ MI PFF+
Sbjct: 580 PEVISRLP-YGPEVDIWSLGIMVMEMIDAEPPFFN 681
>31885
Length = 529
Score = 59.7 bits (143), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 31/104 (29%), Positives = 57/104 (54%), Gaps = 4/104 (3%)
Frame = -2
Query: 134 IRFYMYELLKALDYCHSKGIMHRDVKPHNVMIDHQQKKLRLIDWGLAEFYHPAQEYNVRV 193
++FY+ +L LDY S+ I+HRD+KP N+++D +Q + D+ +A +
Sbjct: 366 VKFYLCQLALVLDYLRSQKIVHRDIKPDNILLD-EQGHCHVTDFNIATQLEDDELATSTS 190
Query: 194 ASRYFKGPEL----LVDYQMYDYSLDMWSLGCMLASMIFRREPF 233
+R + PE+ + + + Y + +D WSLG L ++ +R PF
Sbjct: 189 GTRPYMAPEVYGVAINERRGYGFPVDWWSLGVSLFELLKKRRPF 58
>30755
Length = 1137
Score = 59.7 bits (143), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 35/110 (31%), Positives = 61/110 (55%), Gaps = 1/110 (0%)
Frame = +2
Query: 127 QILTDFDIRFYMYELLKALDYCHSKGIMHRDVKPHNVMIDHQQKKLRLIDWGLA-EFYHP 185
+I T+ RFY E++ AL Y HS+GI++RD+K N+++D + +++ D+GL E
Sbjct: 17 RIFTEERTRFYGAEIISALGYLHSQGIIYRDLKLENLLLD-KDGHIKVADFGLCKEDITY 193
Query: 186 AQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRREPFFH 235
+ + + PE+L D Y ++D W G ++ MI R PF++
Sbjct: 194 GRTTKTFCGTPEYLAPEVLDDND-YGRAVDWWGTGVVMYEMICGRLPFYN 340
>14420
Length = 528
Score = 58.9 bits (141), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 30/97 (30%), Positives = 53/97 (54%), Gaps = 1/97 (1%)
Frame = +2
Query: 140 ELLKALDYCHSKGIMHRDVKPHNVMIDHQQKKLRLIDWGLAEFYHPAQ-EYNVRVASRYF 198
E L+AL++ H ++HRD+K N+++ ++L D+G P Q + + V + Y+
Sbjct: 221 ECLQALEFLHENQVIHRDIKSDNILLG-MDGSVKLTDFGFCAQLSPEQSKRSTMVGTPYW 397
Query: 199 KGPELLVDYQMYDYSLDMWSLGCMLASMIFRREPFFH 235
PE++ Q Y ++D+WSLG M MI P+ +
Sbjct: 398 MAPEVVTRKQ-YGPTVDIWSLGVMCIEMIEGEPPYLN 505
>03294
Length = 1684
Score = 58.5 bits (140), Expect = 4e-09, Method: Compositional matrix adjust.
Identities = 36/119 (30%), Positives = 60/119 (50%), Gaps = 2/119 (1%)
Frame = -1
Query: 212 YSLDMWSLGCMLASMIFRREPFFHGQDNYDQLVRIAKVLGT--EELYGYLKKYHIDLDPH 269
+ +D+WS+G + A M+ R P F G DQL +I +++GT E+ + K P
Sbjct: 1678 HPVDVWSIGTIFADMLIRT-PIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKL-----PA 1517
Query: 270 FNDILGQHSRKRWENFIHSENRHLVSPEALDLLDKLLRYDHQQRLTAKEAMEHPYFYPV 328
FN + W+ SE + LDL+++ L+ D QR++ K+ ++H YF V
Sbjct: 1516 FNGMF-----PLWKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYFLNV 1355
>18287
Length = 678
Score = 58.2 bits (139), Expect = 5e-09, Method: Compositional matrix adjust.
Identities = 37/116 (31%), Positives = 63/116 (54%)
Frame = -3
Query: 210 YDYSLDMWSLGCMLASMIFRREPFFHGQDNYDQLVRIAKVLGTEELYGYLKKYHIDLDPH 269
YDYS+D+WS+GC+ A ++ RR F Q QL I ++GT + +
Sbjct: 673 YDYSIDIWSVGCIFAELLSRRI-LFQAQGPVQQLDMIINLVGTPRPEDMERA----CEGA 509
Query: 270 FNDILGQHSRKRWENFIHSENRHLVSPEALDLLDKLLRYDHQQRLTAKEAMEHPYF 325
N IL Q R++ +++ + H + EA+ LL ++L + + R++A+EA+ HPY
Sbjct: 508 RNHILNQPFRRQNLLTLYNLSPH-ATHEAVRLLTRMLILNPKNRISAEEALSHPYL 344
>13212
Length = 1067
Score = 57.8 bits (138), Expect = 7e-09, Method: Compositional matrix adjust.
Identities = 51/208 (24%), Positives = 87/208 (41%), Gaps = 7/208 (3%)
Frame = -1
Query: 125 LYQILTDFDIRFYMYELLKALDYCHSKGIMHRDVKPHNVM--IDHQQKKLRLIDWGL-AE 181
L + +T+ I + +E+ ALD+ H ++HRD+K NV+ ID + ++L D+G+ A+
Sbjct: 1001 LEKPMTEAQICYVCHEMCMALDFLHRHHVIHRDIKAGNVLLTIDGE---VKLADFGVSAK 831
Query: 182 FYHPAQEYNVRVASRYFKGPELLVDYQM----YDYSLDMWSLGCMLASMIFRREPFFHGQ 237
Q+ + + + Y+ PE+++ + YD+ D+WSLG L + EP
Sbjct: 830 NTQTQQKRDTFIGTPYWMAPEVVLCETLKDTPYDFKADIWSLGVTLIEFA-QIEPPNKEM 654
Query: 238 DNYDQLVRIAKVLGTEELYGYLKKYHIDLDPHFNDILGQHSRKRWENFIHSENRHLVSPE 297
L++I H +D K+W
Sbjct: 653 HPMRVLIKI----------------------HKSDPPTLEKPKKWTKLFK---------- 570
Query: 298 ALDLLDKLLRYDHQQRLTAKEAMEHPYF 325
D + K L D R TA E +EHP+
Sbjct: 569 --DFIAKCLVKDPNLRPTAAELLEHPFM 492
>19761
Length = 473
Score = 57.0 bits (136), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 37/125 (29%), Positives = 65/125 (52%), Gaps = 3/125 (2%)
Frame = -3
Query: 134 IRFYMYELLKALDYCHSKG--IMHRDVKPHNVMIDHQQKKLRLIDWGLA-EFYHPAQEYN 190
I ++ + AL+Y H+ I+HRD+KP N+ + ++ +RL D GLA + PA
Sbjct: 417 IVCWLMQTASALNYMHTHTPVILHRDLKPQNIYVT-EKGDVRLGDLGLARKLTGPADFAT 241
Query: 191 VRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRREPFFHGQDNYDQLVRIAKVL 250
+V + + PE+L Q Y+ D+WSLGC+ + ++ G D + + +V+
Sbjct: 240 SQVGTIMYLSPEIL-SQQPYNSKSDIWSLGCVFYDITGKK-----GSDEMGVMFLLVQVM 79
Query: 251 GTEEL 255
G +L
Sbjct: 78 GGRKL 64
>26711
Length = 405
Score = 56.6 bits (135), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 28/95 (29%), Positives = 54/95 (56%), Gaps = 1/95 (1%)
Frame = -2
Query: 140 ELLKALDYCHSKGIMHRDVKPHNVMIDHQQ-KKLRLIDWGLAEFYHPAQEYNVRVASRYF 198
++L L + H++G++H D+KP N+++ + ++LID+GLA +P QE + + F
Sbjct: 392 QVLDILQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARKLYPPQETFLNHGTPGF 213
Query: 199 KGPELLVDYQMYDYSLDMWSLGCMLASMIFRREPF 233
PE L D + + D+W +G + ++ + PF
Sbjct: 212 TSPEAL-DVKPISTASDVWGVGVLAYILLSGQSPF 111
>27405
Length = 532
Score = 56.6 bits (135), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 32/114 (28%), Positives = 63/114 (55%), Gaps = 6/114 (5%)
Frame = -3
Query: 108 KTP---ALVFEYINNTDFK---QLYQILTDFDIRFYMYELLKALDYCHSKGIMHRDVKPH 161
+TP + + +N D + + T+ ++RFY E++ L++ HS+ +++RD+KP
Sbjct: 344 QTPEKLCFILDLMNGGDLHYHLSQHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPA 165
Query: 162 NVMIDHQQKKLRLIDWGLAEFYHPAQEYNVRVASRYFKGPELLVDYQMYDYSLD 215
N+++D + +R+ D GLA + + + V + + PE+L+ Q YD S D
Sbjct: 164 NILLD-ENGHVRISDLGLACDFSKKKPH-ASVGTHGYMAPEVLMKGQAYDSSAD 9
>18921
Length = 697
Score = 55.8 bits (133), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 34/129 (26%), Positives = 63/129 (48%), Gaps = 5/129 (3%)
Frame = +2
Query: 112 LVFEYINNTDFKQLYQI----LTDFDIRFYMYELLKALDYCHSKGIMHRDVKPHNVMIDH 167
+V EY + ++ L + +I +Y LK L Y HS+ +HRD+K N+++++
Sbjct: 245 IVMEYCGAGSVSDIMRLRNKTLVEREIATILYYTLKGLXYLHSRRKIHRDIKAGNILLNN 424
Query: 168 QQKKLRLIDWGLA-EFYHPAQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASM 226
+ +L D+G+A + + N + + Y+ PE++ + YD D+WSLG M
Sbjct: 425 EGHA-KLADFGVAGQLTDTMAKRNTVIGTPYWMAPEVIQEIG-YDCVADIWSLGITALEM 598
Query: 227 IFRREPFFH 235
+ P
Sbjct: 599 AEGKPPVME 625
>09606
Length = 1300
Score = 55.5 bits (132), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 54/222 (24%), Positives = 90/222 (40%), Gaps = 25/222 (11%)
Frame = -3
Query: 129 LTDFDIRFYMYELLKALDYCHSKGIMHRDVKPHNVMIDHQQKKLRLIDWGLAE------- 181
L + IR + L+ L Y HS GI+ D++P V++D L+ D+GL++
Sbjct: 842 LPETSIRDFGIHLVTGLHYIHSLGILFHDLRPSKVLLD-TSGVLKFADFGLSKVEGENLE 666
Query: 182 -----FYHPAQEYNVRVASRYFK-----------GPELLVDYQMYDYSL--DMWSLGCML 223
F ++N++ A K PE+ +Q + S+ D+W+LGC+
Sbjct: 665 ELFFKFAEAGDQWNIQSAEEMMKQVPTSGSPTYMAPEV---FQGAEPSIMSDLWALGCVF 495
Query: 224 ASMIFRREPFFHGQDNYDQLVRIAKVLGTEELYGYLKKYHIDLDPHFNDILGQHSRKRWE 283
M PF + YD + KVL E +K + P
Sbjct: 494 YEMFSGHPPFL--GETYD--ITKDKVLNKEFPLPKVKGSRLSAKP--------------- 372
Query: 284 NFIHSENRHLVSPEALDLLDKLLRYDHQQRLTAKEAMEHPYF 325
SPE L+LL+ LL+ D +RL+ ++H ++
Sbjct: 371 -----------SPEFLNLLESLLQKDSTRRLSWASLVKHAFW 279
>28638
Length = 1458
Score = 54.3 bits (129), Expect = 7e-08, Method: Compositional matrix adjust.
Identities = 25/75 (33%), Positives = 47/75 (62%), Gaps = 1/75 (1%)
Frame = -1
Query: 153 IMHRDVKPHNVMIDHQQKK-LRLIDWGLAEFYHPAQEYNVRVASRYFKGPELLVDYQMYD 211
I+H D+KP N+++ + ++ ++++D+G Q + SR+++ PE+L+ YD
Sbjct: 768 IIHCDLKPENILLCNPKRSAIKIVDFG--SSCQLGQRIYQYIQSRFYRSPEVLLGVP-YD 598
Query: 212 YSLDMWSLGCMLASM 226
++DMWSLGC+L M
Sbjct: 597 LAIDMWSLGCILVEM 553
Score = 30.4 bits (67), Expect = 1.2, Method: Compositional matrix adjust.
Identities = 29/139 (20%), Positives = 57/139 (41%), Gaps = 30/139 (21%)
Frame = -2
Query: 217 WSLGCMLASMIFRR----EPFFHGQDNYDQLVRIAKVLGTEELY----GYLKKYHIDL-- 266
W L C ++ + R P F G + +DQ+++I +VLG + + + DL
Sbjct: 596 WPLTCGXWAVYWWRCTXGNPLFAGSNEFDQMMKIVEVLGVPPRHILDQAQKTRKYFDLLP 417
Query: 267 -------DPHFNDILGQHSRKRWENFIHSE-----NRHLVSP--------EALDLLDKLL 306
P N S ++ + +E R + P + DL+ ++L
Sbjct: 416 DGTYAPKKPRDNKKYKSPSSRKLHEVLGAEKGGPGGRRMGEPGHTVADYLKFKDLILRML 237
Query: 307 RYDHQQRLTAKEAMEHPYF 325
+D + R++ A++H +F
Sbjct: 236 DFDPKTRISPYYALQHNFF 180
>13592
Length = 980
Score = 53.9 bits (128), Expect = 9e-08, Method: Compositional matrix adjust.
Identities = 58/299 (19%), Positives = 111/299 (37%), Gaps = 19/299 (6%)
Frame = +2
Query: 45 KLGRGKYSEVFEAINITNNEXXXXXXXXXXXXXXXXXXXXXXXNLRGGTNIIKLIDTVKD 104
K+G+G++ +V+ A+N E L+ +K+++ +K
Sbjct: 5 KIGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETRA--------LKNVAEELKILEGIKH 160
Query: 105 P---------VSKTPALVF-EYINNTDFKQLYQI---LTDFDIRFYMYELLKALDYCHSK 151
V + L+F E + + L ++ L + R + +LL + H
Sbjct: 161 KNLVRYYGIEVHREELLIFMELCSEGTLESLVELTGGLPEALSRRFTAQLLSGVAELHKH 340
Query: 152 GIMHRDVKPHNVMIDHQQKKLRLIDWGLAEFYHP----AQEYNVRVASRYFKGPELLVDY 207
GI+HRD+K N+ + L+L D+G A E V ++ + PE+
Sbjct: 341 GIVHRDIKTANIFLVDGSNSLKLGDFGSAVKIQAHTTVPGELQGYVGTQAYMAPEVFTKT 520
Query: 208 QMYDYS--LDMWSLGCMLASMIFRREPFFHGQDNYDQLVRIAKVLGTEELYGYLKKYHID 265
+ D+WS+GC++ M + P+ N+ + ++ +
Sbjct: 521 NSDGHGRLADIWSVGCVVVEMASGKRPWAQFDSNFQIMFKVG----------------MG 652
Query: 266 LDPHFNDILGQHSRKRWENFIHSENRHLVSPEALDLLDKLLRYDHQQRLTAKEAMEHPY 324
P + L Q E D +D L++D +QRL+A E +E +
Sbjct: 653 EKPQAPESLSQ--------------------EGHDFIDHCLQHDPKQRLSAIELLEQNF 769
>03240
Length = 1683
Score = 53.9 bits (128), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 42/171 (24%), Positives = 67/171 (39%), Gaps = 48/171 (28%)
Frame = -3
Query: 112 LVFEYINNTDFKQL---YQILTDFDIRFYMYELLKALDYCHSKGIMHRDVKPHNVMIDHQ 168
V +Y+ D L +IL + RFY+ EL++A++ H G +HRD+KP N++ID +
Sbjct: 1060 FVMDYVPGGDLMGLLIRMEILDEPLARFYVAELVQAIESVHRMGFIHRDIKPDNILID-R 884
Query: 169 QKKLRLIDWGL------------------------------------AEFYHPAQEYNVR 192
++L D+GL E P + R
Sbjct: 883 NGHIKLTDFGLCTGFRWTHNSKYYQRDGTHARQDSMEVKCQLDEQCQCEILKPLERRRKR 704
Query: 193 ---------VASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRREPFF 234
V + + PE+L Y D WS+G +L M+ PF+
Sbjct: 703 EQRCLAHSLVGTPNYIAPEVLSRLGGYTSVCDWWSVGVILFEMLVGHPPFY 551
>18484
Length = 635
Score = 53.5 bits (127), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 34/110 (30%), Positives = 59/110 (53%), Gaps = 6/110 (5%)
Frame = +1
Query: 136 FYMYELLKALDYCHSKGIMHRDVKPHNVMIDHQQKKLRLIDWGLAEFYHPAQEYNVRVAS 195
FY E+ L + H +GI++RD+K NVM+D + +++ D+G+ + + +
Sbjct: 55 FYAAEIAVGLFFLHDQGIIYRDLKLDNVMLD-SEGHIKIADFGMCK-----EGMTGDATT 216
Query: 196 RYFKG------PELLVDYQMYDYSLDMWSLGCMLASMIFRREPFFHGQDN 239
R F G PE+++ YQ Y S+D W+ G +L M+ + P F G+D
Sbjct: 217 RTFCGTPDYIAPEIVL-YQPYSKSVDWWAYGVLLFEMLAGQPP-FDGEDE 360
>19094
Length = 898
Score = 52.8 bits (125), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 30/101 (29%), Positives = 55/101 (54%), Gaps = 1/101 (0%)
Frame = +1
Query: 127 QILTDFDIRFYMYELLKALDYCHSKGIMHRDVKPHNVMIDHQQKKLRLIDWGLA-EFYHP 185
+ L + +I +Y LK L Y HS+ +HRD+K N++++++ +L D+G+A +
Sbjct: 43 KTLVEREIATILYYTLKGL*YLHSRRKIHRDIKAGNILLNNEGHA-KLADFGVAGQLTDT 219
Query: 186 AQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASM 226
+ N + + Y+ PE++ + YD D+WSLG M
Sbjct: 220 MAKRNTVIGTPYWMAPEVIQEIG-YDCVADIWSLGITALEM 339
>21433
Length = 590
Score = 52.4 bits (124), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 46/172 (26%), Positives = 80/172 (46%)
Frame = +2
Query: 137 YMYELLKALDYCHSKGIMHRDVKPHNVMIDHQQKKLRLIDWGLAEFYHPAQEYNVRVASR 196
Y+Y+L AL+YCH + ++HRD+KP N+++ + L++ D+G + + P+ +
Sbjct: 182 YIYQLSSALEYCHYRKVIHRDIKPENLLLG-LKGDLKIADFGWS-VHAPSSRRTTMCGTL 355
Query: 197 YFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRREPFFHGQDNYDQLVRIAKVLGTEELY 256
+ PE +V+ + +D ++D+WSLG + Y+ LV GT L
Sbjct: 356 DYLPPE-MVEGKTHDENVDLWSLGVLC----------------YEFLV------GTPPLR 466
Query: 257 GYLKKYHIDLDPHFNDILGQHSRKRWENFIHSENRHLVSPEALDLLDKLLRY 308
+ P RW S + +V+P A DL+ KLLR+
Sbjct: 467 PSPTRPPTPASP------------RWT----SGSPSIVTPGARDLISKLLRH 574
>18401
Length = 463
Score = 50.1 bits (118), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 36/146 (24%), Positives = 74/146 (50%), Gaps = 11/146 (7%)
Frame = -3
Query: 193 VASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRREPFFHGQDNYDQLVRIAKVLGT 252
V++R+++ PE++++ + + D+WS+GC++ ++ F DN + L + ++LG+
Sbjct: 449 VSTRHYRAPEVILELG-WSHPCDVWSVGCIMFE-LYTGYTLFQTHDNKEHLAMMERILGS 276
Query: 253 EELYGYLKK-------YHIDLDPHFNDILGQHSRKRWENFIH----SENRHLVSPEALDL 301
Y KK +H LD + ++ R+ + + EN+ + DL
Sbjct: 275 LP-YRMAKKTKKQKYFHHGRLDVPERSSMARYVRENTKPLLRYVKDRENKD--HQQLFDL 105
Query: 302 LDKLLRYDHQQRLTAKEAMEHPYFYP 327
+ KLL Y+ R + +A++HP+F P
Sbjct: 104 MKKLLAYEASSRYSLLQALQHPFFSP 27
>07940
Length = 1336
Score = 45.8 bits (107), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 29/105 (27%), Positives = 58/105 (55%), Gaps = 4/105 (3%)
Frame = -3
Query: 123 KQLYQILTDFDIRFYMYELLKALDYCHSKGIMHRDVKPHNVMIDHQQKKLRLIDWGLA-- 180
+ + ++LT D+ Y Y++ + ++Y SK +HRD+ NV++ ++ L++ D+GL
Sbjct: 374 QDMLKMLTPKDLISYAYQVARGMEYLASKQCIHRDLAARNVLV-AEEYVLKIADFGLTRN 198
Query: 181 --EFYHPAQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCML 223
+F + + + R+ ++ PE L D + Y D+WS G +L
Sbjct: 197 LQQFDYYRKTTDGRLPVKWM-APEALFDRK-YTSKSDVWSYGVLL 69
>13078
Length = 773
Score = 45.1 bits (105), Expect = 4e-05, Method: Compositional matrix adjust.
Identities = 34/125 (27%), Positives = 58/125 (46%), Gaps = 13/125 (10%)
Frame = -1
Query: 214 LDMWSLGCMLASMIFRREPFFHGQDNYDQLVRIAKVLGTEELYGYLKK-------YHIDL 266
D+WS+GC++ ++ F DN + L + ++LG+ Y KK YH L
Sbjct: 734 CDVWSIGCIMFE-LYTGYTLFQTHDNKEHLAMMERILGSLP-YRMAKKTKKQKYFYHGRL 561
Query: 267 DPHFNDILGQHSRKRWENFIHSENRHLVSP------EALDLLDKLLRYDHQQRLTAKEAM 320
D G++ R + R++ P + DL+DK+L Y+ R + ++AM
Sbjct: 560 DWDEKSSAGRYVRDN----VKPLRRYVKDPDNEDHQQLFDLMDKMLSYEVSTRYSLRQAM 393
Query: 321 EHPYF 325
HP+F
Sbjct: 392 RHPFF 378
>37602
Length = 804
Score = 45.1 bits (105), Expect = 5e-05, Method: Compositional matrix adjust.
Identities = 26/90 (28%), Positives = 43/90 (47%), Gaps = 3/90 (3%)
Frame = -1
Query: 112 LVFEYINNTDFKQLYQI---LTDFDIRFYMYELLKALDYCHSKGIMHRDVKPHNVMIDHQ 168
+ EY + +Y + LT+ I F E LK L Y H +G MHRD+K N+++ +
Sbjct: 288 IAMEYCGGGSMQDIYHVTGPLTEPQIAFVCRETLKGLHYLHRRGKMHRDIKGANILLTEE 109
Query: 169 QKKLRLIDWGLAEFYHPAQEYNVRVASRYF 198
D LA+F+ + ++ V + F
Sbjct: 108 G------DVKLADFWRVSSNHSHNVQKKVF 37
>31489
Length = 329
Score = 43.9 bits (102), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 26/77 (33%), Positives = 47/77 (61%), Gaps = 6/77 (7%)
Frame = +3
Query: 94 NIIKLIDTVKDPVS----KTPALVFEYINNTDFKQLY--QILTDFDIRFYMYELLKALDY 147
NII + + +K S K +VF+ + + + +Y Q LT+ IR+++Y++L+ L Y
Sbjct: 33 NIISIREILKPKDSYHDFKDIHVVFDLMESDLHRIIYSDQPLTEEHIRYFLYQILRGLKY 212
Query: 148 CHSKGIMHRDVKPHNVM 164
HS ++HRD+KP N++
Sbjct: 213 IHSANVVHRDLKPSNLL 263
>13066
Length = 551
Score = 42.7 bits (99), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 25/89 (28%), Positives = 41/89 (46%), Gaps = 3/89 (3%)
Frame = +3
Query: 135 RFYMYELLKALDYCHSKGIMHRDVKPHNVMI-DHQQKKLRLIDWGLAEFYHPAQEYNVR- 192
+ + Y++ AL+Y HS + HRD+K N+++ H KL + A ++Y R
Sbjct: 285 KIWFYQMTTALNYLHSYDVAHRDLKCENILLSSHFNVKLADFGFACACITESGEKYMSRT 464
Query: 193 -VASRYFKGPELLVDYQMYDYSLDMWSLG 220
S + PE++ D WSLG
Sbjct: 465 YCGSAAYAAPEIVYGAPYAPKVADAWSLG 551
>11185
Length = 473
Score = 42.4 bits (98), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 31/120 (25%), Positives = 53/120 (44%), Gaps = 25/120 (20%)
Frame = +1
Query: 133 DIRFYMYELLKALDYCHSKGIMHRDVKPHNVMIDHQQKKLRLIDWGLAE----------- 181
IR + L+ L Y HS GI+ D++P V++D L+ D+GL++
Sbjct: 4 SIRDFGIHLVTGLHYIHSLGILFHDLRPSKVLLD-TSGVLKFADFGLSKVEGENLEELFF 180
Query: 182 -FYHPAQEYNVRVASRYFK-----------GPELLVDYQMYDYSL--DMWSLGCMLASMI 227
F ++N++ A K PE+ +Q + S+ D+W+LGC+ M
Sbjct: 181 KFAEAGDQWNIQSAEEMMKQVPTSGSPTYMAPEV---FQGAEPSIMSDLWALGCVFYEMF 351
>01718
Length = 959
Score = 42.4 bits (98), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 50/208 (24%), Positives = 89/208 (42%), Gaps = 9/208 (4%)
Frame = +3
Query: 31 VPSWGNQDDYQLVRKLGRGKYSEVFEAINITNNEXXXXXXXXXXXXXXXXXXXXXXXNLR 90
V + DD+ + K+G G +SEVF+ + + N
Sbjct: 129 VSALTRLDDF-ICEKIGAGFFSEVFKVTHRITGQVMALKMNTMTSNRHNMLREVQLLNRL 305
Query: 91 GGTNIIKLIDTVKDPVSKTPALVFEYINNTDFKQLYQILTD---FDIRFYM-YELLKALD 146
NI++ + + AL EYI + + +QL + + + R + L + LD
Sbjct: 306 QHANILRFMGVCVHE-GQLHALT-EYIPSGNLEQLLEKKDEELPWTQRIQLTLGLARGLD 479
Query: 147 YCHSKGIMHRDVKPHNVMI---DHQQKKLRLIDWGLA-EFYHPA-QEYNVRVASRYFKGP 201
Y HS +HRD+ N++I D+ + D+GLA + P +E V S Y+ P
Sbjct: 480 YLHSTRFIHRDLTSKNILIRREDNHGYHAVIADFGLATKIPDPLDKEKLPTVGSPYWMAP 659
Query: 202 ELLVDYQMYDYSLDMWSLGCMLASMIFR 229
E+L + Y+ D++S+G ++ + R
Sbjct: 660 EVL-NGHFYNERADLFSVGIIMCEITAR 740
>05084
Length = 1324
Score = 42.4 bits (98), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 27/91 (29%), Positives = 41/91 (45%), Gaps = 1/91 (1%)
Frame = +2
Query: 236 GQDNYDQLVRIAKVLGTEELYGYLKKYHIDLDPHFNDI-LGQHSRKRWENFIHSENRHLV 294
G DQLV I KVLGT ++ +++P++++ Q W R
Sbjct: 8 GDSGVDQLVEIIKVLGTPT-----REQIREMNPNYSEFKFPQIKAHPWTKVF----RPRT 160
Query: 295 SPEALDLLDKLLRYDHQQRLTAKEAMEHPYF 325
PEA+ L+ +LL Y R+ EA H +F
Sbjct: 161 PPEAIQLVSRLLEYTPSARIQPMEACAHAFF 253
>26009
Length = 886
Score = 42.0 bits (97), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 16/33 (48%), Positives = 25/33 (75%)
Frame = +3
Query: 133 DIRFYMYELLKALDYCHSKGIMHRDVKPHNVMI 165
+ + M +L+ ALD+ HSK ++HRD+KP NV+I
Sbjct: 714 EAKSVMKQLVSALDFMHSKQLVHRDIKPENVLI 812
>17975
Length = 449
Score = 41.6 bits (96), Expect = 5e-04, Method: Compositional matrix adjust.
Identities = 17/55 (30%), Positives = 33/55 (60%)
Frame = +3
Query: 137 YMYELLKALDYCHSKGIMHRDVKPHNVMIDHQQKKLRLIDWGLAEFYHPAQEYNV 191
Y ++++A+ YCH ++HRD+KP NV+ + ++L D+G + A+ N+
Sbjct: 282 YFRQIVEAISYCHKLHVVHRDLKPENVVFFEKPGLVKLTDFGFSTCLLQAKA*NI 446
>00715
Length = 1788
Score = 40.8 bits (94), Expect = 9e-04, Method: Compositional matrix adjust.
Identities = 37/149 (24%), Positives = 61/149 (40%), Gaps = 27/149 (18%)
Frame = +1
Query: 112 LVFEYINNTDFKQL---YQILTDFDIRFYM-YELLKALDYCHSKGIMHRDVKPHNVMIDH 167
L EY+ + + + +Q D +R + ++ + L Y HS I+H D+KP N ++
Sbjct: 166 LAMEYVGPLNLQTILNDHQQDIDSSMRLSLALQMARGLHYLHSINIVHLDLKPANCLLT- 342
Query: 168 QQKKLRLIDWGLAEFYHP-----------------------AQEYNVRVASRYFKGPELL 204
+ KLR+ D+G P N + ++ PELL
Sbjct: 343 RDLKLRIADFGCCHQLTPTGLDMGEREGGMAGNELELTPVQGAWKNELAGTLAYRAPELL 522
Query: 205 VDYQMYDYSLDMWSLGCMLASMIFRREPF 233
Q S D++SLG L M R+ P+
Sbjct: 523 KGLQPSVRS-DVYSLGITLWQMCTRQGPY 606
>00392
Length = 668
Score = 40.4 bits (93), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 25/93 (26%), Positives = 53/93 (56%), Gaps = 3/93 (3%)
Frame = +3
Query: 134 IRFYMYELLKALDYCHSKG--IMHRDVKPHNVMIDHQQKKLRLIDWGLAEFYHPAQEYNV 191
++ + ++LK L + H++ ++HRD+K N+ I +++ D GLA + + +V
Sbjct: 252 LKNWCRQVLKGLYFLHTRTPPVIHRDLKCDNIFITGPTGSVKIGDLGLATLKNQSFAKSV 431
Query: 192 RVASRYFKGPELLVDYQMYDYSLDMWSLG-CML 223
+ + F PE+ ++ YD ++D+++ G CML
Sbjct: 432 -IGTPEFMAPEMYEEH--YDEAVDVYAFGMCML 521
>12453
Length = 680
Score = 37.7 bits (86), Expect = 0.007, Method: Compositional matrix adjust.
Identities = 31/113 (27%), Positives = 50/113 (44%), Gaps = 6/113 (5%)
Frame = +3
Query: 219 LGCMLASMIFRREPFFHGQDNYDQLVRIAKVLGTEELYGYLKKYHIDLDPHFNDILGQHS 278
+GC+ M R P F G D+L I K LGT I +P F +
Sbjct: 6 VGCIFYEMACGR-PLFPGSTVEDELHLIFKTLGTPTEDSL---PSISRNPDFLAL----- 158
Query: 279 RKRWENFIHSENRHLVS------PEALDLLDKLLRYDHQQRLTAKEAMEHPYF 325
N H + L++ + LDLL K L+Y+ + R++A ++++H +F
Sbjct: 159 -----NLPHYQGEALITIAPRLDSDGLDLLAKFLKYNAKIRVSAADSLKHSFF 302
>14116
Length = 1017
Score = 37.4 bits (85), Expect = 0.009, Method: Compositional matrix adjust.
Identities = 24/102 (23%), Positives = 50/102 (49%), Gaps = 5/102 (4%)
Frame = -1
Query: 133 DIRFYMYELLKALDYCHSKGIMHRDVKPHNVMIDHQQKKLRLIDWGLA-----EFYHPAQ 187
D+ Y ++ + +DY +HRD+ N M+D + +++ D+GLA + Y+ ++
Sbjct: 318 DLIMYGVDIARGMDYLAGLKFVHRDLAARNCMLD-EDFHVKVADFGLARDIYEKEYYSSE 142
Query: 188 EYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFR 229
++ ++ L + YD D+WS G +L ++ R
Sbjct: 141 NKKAKLPVKWMALESL--EKGNYDSKTDVWSYGVVLWELLTR 22
>32359
Length = 928
Score = 28.5 bits (62), Expect(2) = 0.010, Method: Compositional matrix adjust.
Identities = 15/49 (30%), Positives = 26/49 (53%), Gaps = 6/49 (12%)
Frame = -1
Query: 112 LVFEYINNTDFK------QLYQILTDFDIRFYMYELLKALDYCHSKGIM 154
LV EY+ T ++ + Q + I+ YMY+L ++L Y HS+ +
Sbjct: 202 LVLEYVPETVYRVARHYSKSKQTIPILYIKLYMYQLFRSLAYIHSQACV 56
Score = 27.3 bits (59), Expect(2) = 0.010, Method: Compositional matrix adjust.
Identities = 9/21 (42%), Positives = 15/21 (71%)
Frame = -3
Query: 152 GIMHRDVKPHNVMIDHQQKKL 172
G+ HRD+KP N+++D + L
Sbjct: 65 GVCHRDIKPQNLLLDPETGVL 3
>27546
Length = 426
Score = 37.4 bits (85), Expect = 0.010, Method: Compositional matrix adjust.
Identities = 16/58 (27%), Positives = 35/58 (60%)
Frame = -1
Query: 135 RFYMYELLKALDYCHSKGIMHRDVKPHNVMIDHQQKKLRLIDWGLAEFYHPAQEYNVR 192
+ + +++ KAL Y HS I HRD+K N+++ ++ +++ D+G A + A +++
Sbjct: 171 KVWFFQMAKALQYLHSHDIAHRDLKCENILLS-KRLNVKIADFGFARYCRDAAGMDLK 1
>06358
Length = 1517
Score = 36.6 bits (83), Expect = 0.014, Method: Compositional matrix adjust.
Identities = 34/127 (26%), Positives = 58/127 (45%), Gaps = 20/127 (15%)
Frame = +3
Query: 129 LTDFDIRFYMYELLKALDYCHSKG-IMHRDVKPHNVMIDHQQKKLRLIDWGLA--EFY-- 183
L D +I+ + ++ +AL + H+ +MHR+V P +M+ +L W LA EF
Sbjct: 351 LYDVEIKHGLLQVTEALGFLHNDAKMMHRNVCPEAIMLT------KLGSWKLAGYEFCVR 512
Query: 184 ----------HPAQEYNVRVASRY-----FKGPELLVDYQMYDYSLDMWSLGCMLASMIF 228
+P E+ +A F PE ++ Q S DM+SLG ++ S+
Sbjct: 513 SSDPQSTDPSYPFYEWRSDIAPVTQPHLDFMAPEYVLTMQCGTGS-DMFSLGLLVYSVFA 689
Query: 229 RREPFFH 235
+ +P F
Sbjct: 690 KGKPLFE 710
>01106
Length = 878
Score = 36.2 bits (82), Expect = 0.019, Method: Compositional matrix adjust.
Identities = 19/60 (31%), Positives = 35/60 (58%), Gaps = 5/60 (8%)
Frame = +3
Query: 111 ALVFEYINNTDFKQL----YQILTDFDIRFYMYELLKALDYCHSKG-IMHRDVKPHNVMI 165
A+VFE + K + YQ + +++ + ++L+ L Y H+K I+H D+KP N++I
Sbjct: 570 AMVFEVLGYNLLKLIIRSNYQGIPIHNVKLIIRQVLEGLSYMHAKCRIIHTDIKPENILI 749
>18481
Length = 437
Score = 36.2 bits (82), Expect = 0.019, Method: Compositional matrix adjust.
Identities = 18/50 (36%), Positives = 30/50 (60%), Gaps = 2/50 (4%)
Frame = -1
Query: 140 ELLKALDYCHSKGIMHRDVKPHNVM--IDHQQKKLRLIDWGLAEFYHPAQ 187
+LL L++ H K +HRD+KP N + + +L +ID+GL++ Y Q
Sbjct: 173 QLLSRLEFIHQKCFIHRDLKPDNFLMGLGRHCHRLYIIDFGLSKRYKDTQ 24
>02638
Length = 1490
Score = 36.2 bits (82), Expect = 0.021, Method: Compositional matrix adjust.
Identities = 33/128 (25%), Positives = 52/128 (40%)
Frame = +1
Query: 198 FKGPELLVDYQMYDYSLDMWSLGCMLASMIFRREPFFHGQDNYDQLVRIAKVLGTEELYG 257
F PE+L + Y + D+WS+GC++ M R P ++ D + L I K+ +
Sbjct: 34 FMAPEVL-RGESYGRACDVWSVGCVMIEMCTCRPP-WNSHDISNHLALIFKIASS----- 192
Query: 258 YLKKYHIDLDPHFNDILGQHSRKRWENFIHSENRHLVSPEALDLLDKLLRYDHQQRLTAK 317
+D P EN +SP DL+ + L D R +AK
Sbjct: 193 ------VDPPP------------------IPEN---MSPPVRDLMLRCLEQDSDFRPSAK 291
Query: 318 EAMEHPYF 325
+ + HP F
Sbjct: 292 DLLMHPLF 315
>21800
Length = 855
Score = 35.4 bits (80), Expect = 0.030, Method: Compositional matrix adjust.
Identities = 18/60 (30%), Positives = 35/60 (58%), Gaps = 5/60 (8%)
Frame = +2
Query: 111 ALVFEYINNTDFKQL----YQILTDFDIRFYMYELLKALDYCHSK-GIMHRDVKPHNVMI 165
+VFE + K + YQ + +++ + ++L+ L+Y H+K I+H D+KP N++I
Sbjct: 557 CMVFEVLGYNLLKLIIRSNYQGIPVHNVKLIIRQVLEGLNYLHAKCNIIHTDIKPENILI 736
>28157
Length = 400
Score = 35.4 bits (80), Expect = 0.037, Method: Compositional matrix adjust.
Identities = 29/104 (27%), Positives = 47/104 (45%), Gaps = 13/104 (12%)
Frame = +3
Query: 94 NIIKLIDTVKD-PVSKTPALVFEYINNTDFKQLYQIL---------TDFDIRFYMYELLK 143
NI+ L +D PV LV EY + LY +L T ++ +
Sbjct: 93 NIVCLYGACRDHPV----CLVMEY---AEGGSLYNVLHGSGPQPQYTAAHAMNWLLQCAL 251
Query: 144 ALDYCHS---KGIMHRDVKPHNVMIDHQQKKLRLIDWGLAEFYH 184
++Y H K ++HRD+KP N+++ KL++ D+G A H
Sbjct: 252 GVEYLHGMKPKALIHRDLKPPNLLLIQCGTKLKICDFGTACDIH 383
>20773
Length = 391
Score = 33.5 bits (75), Expect = 0.13, Method: Compositional matrix adjust.
Identities = 18/50 (36%), Positives = 27/50 (54%)
Frame = -1
Query: 275 GQHSRKRWENFIHSENRHLVSPEALDLLDKLLRYDHQQRLTAKEAMEHPY 324
G H R+ F H+ +V+ +L+ +LL YD QRLT A+ HP+
Sbjct: 370 GLHRRRSRPVFPHTT---VVTQHFYNLVQRLLTYDPSQRLTPDLALSHPF 230
>15931
Length = 447
Score = 33.1 bits (74), Expect = 0.19, Method: Compositional matrix adjust.
Identities = 12/29 (41%), Positives = 20/29 (68%)
Frame = +1
Query: 297 EALDLLDKLLRYDHQQRLTAKEAMEHPYF 325
+ DL+DK+L Y+ R + ++AM HP+F
Sbjct: 70 QLFDLMDKMLSYEVSTRYSLRQAMRHPFF 156
>26909
Length = 394
Score = 32.7 bits (73), Expect = 0.21, Method: Compositional matrix adjust.
Identities = 34/127 (26%), Positives = 57/127 (44%), Gaps = 15/127 (11%)
Frame = +2
Query: 227 IFRREPFFHGQD---------NYDQLVRIAKVLG--TEELYGYLKKYHIDLDPHFNDILG 275
+ EP FH + ++DQL RI V+G E+ + +++ P +
Sbjct: 14 LLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFPQEKDWEDIRRM-----PEHQQLTK 178
Query: 276 QHSRKRWEN--FIHSENRHLVSPE--ALDLLDKLLRYDHQQRLTAKEAMEHPYFYPVVKE 331
R + N + +H V + A LL KLL D +R+T+++AM+ PYF E
Sbjct: 179 DFKRSSYVNCNLMKYMEKHKVKADSKAFHLLQKLLTMDPVKRITSEQAMKDPYFL----E 346
Query: 332 QSQPCAD 338
+ P +D
Sbjct: 347 EPLPSSD 367
>19301
Length = 712
Score = 32.7 bits (73), Expect = 0.24, Method: Compositional matrix adjust.
Identities = 19/76 (25%), Positives = 40/76 (52%), Gaps = 6/76 (7%)
Frame = +2
Query: 111 ALVFEYINNTDFKQLYQILTDFD------IRFYMYELLKALDYCHSKGIMHRDVKPHNVM 164
++ EY + QLY++L D + + ++ ++Y HS I+HRD+K NV+
Sbjct: 497 CIIMEY---CPYGQLYEVLRDGKEIPPALVLDWSKQIASGMNYLHSHKIIHRDLKSPNVL 667
Query: 165 IDHQQKKLRLIDWGLA 180
+ + +++ D+G +
Sbjct: 668 V-AKNDVVKISDFGTS 712
>35032
Length = 465
Score = 32.7 bits (73), Expect = 0.24, Method: Compositional matrix adjust.
Identities = 13/27 (48%), Positives = 18/27 (66%)
Frame = +3
Query: 300 DLLDKLLRYDHQQRLTAKEAMEHPYFY 326
DL+ +LL YD +RLT A+ HP+ Y
Sbjct: 147 DLVKRLLNYDPSKRLTPXXALAHPFLY 227
>18663
Length = 600
Score = 30.8 bits (68), Expect = 0.90, Method: Compositional matrix adjust.
Identities = 25/84 (29%), Positives = 37/84 (44%), Gaps = 18/84 (21%)
Frame = +2
Query: 200 GPELLVDYQMYDYSLDMWSLGCMLASMIFRREPF--FHGQDNYDQ-------------LV 244
PE+L + Y +S+D W+LG +L M+ R PF +N DQ +
Sbjct: 32 APEILRG-EDYGFSVDWWALGVLLYEMLAGRSPFDIAGASENPDQNTEDYLFQVILEKTI 208
Query: 245 RIAKVLGTEE---LYGYLKKYHID 265
RI + L + L G+L K D
Sbjct: 209 RIPRSLSVKAASVLKGFLNKNPAD 280
>14104
Length = 573
Score = 30.4 bits (67), Expect = 1.1, Method: Compositional matrix adjust.
Identities = 10/32 (31%), Positives = 19/32 (59%)
Frame = +1
Query: 294 VSPEALDLLDKLLRYDHQQRLTAKEAMEHPYF 325
+P+A+ + L+ D +RLT + ++HPY
Sbjct: 88 AAPQAMSFMQSCLKMDPAERLTCHQLLQHPYM 183
>29590
Length = 320
Score = 30.4 bits (67), Expect = 1.1, Method: Composition-based stats.
Identities = 17/58 (29%), Positives = 27/58 (46%)
Frame = +3
Query: 176 DWGLAEFYHPAQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRREPF 233
D G A + ++ + + + PE+L DY+ DMWSLG + M+ PF
Sbjct: 6 DLGFACLTNTGEDIRDIIGTPDYVAPEVL-DYEPLSIQTDMWSLGVLSYVMLTACSPF 176
>37063
Length = 455
Score = 30.4 bits (67), Expect = 1.1, Method: Compositional matrix adjust.
Identities = 24/79 (30%), Positives = 37/79 (46%), Gaps = 13/79 (16%)
Frame = -2
Query: 158 VKPHNVMIDHQQK--KLRLIDWGLAEFYHP------AQEYNVRVASRYFKGPELLVDYQM 209
+KP N++ +H + L++ D+ LA + E V S + PE+ VD +
Sbjct: 454 LKPENILCEHLDEVVPLKICDFDLASGINCDGDGTKTPELLTPVGSAEYMAPEV-VDAWV 278
Query: 210 -----YDYSLDMWSLGCML 223
YD DMWSLG +L
Sbjct: 277 GESFSYDKRCDMWSLGIIL 221
>12974
Length = 1084
Score = 29.3 bits (64), Expect = 2.6, Method: Compositional matrix adjust.
Identities = 10/31 (32%), Positives = 21/31 (67%)
Frame = +2
Query: 219 LGCMLASMIFRREPFFHGQDNYDQLVRIAKV 249
+GC ++ I +REPF + Y Q++++++V
Sbjct: 824 IGCRISFTIRKREPFHTTVNFYSQMLKLSRV 916
>17644
Length = 463
Score = 28.9 bits (63), Expect = 2.9, Method: Compositional matrix adjust.
Identities = 12/24 (50%), Positives = 16/24 (66%)
Frame = +3
Query: 301 LLDKLLRYDHQQRLTAKEAMEHPY 324
L+ +LL YD QRLT A+ HP+
Sbjct: 90 LVQRLLTYDPSQRLTPDLALSHPF 161
>36481
Length = 806
Score = 28.9 bits (63), Expect = 3.1, Method: Compositional matrix adjust.
Identities = 12/36 (33%), Positives = 22/36 (61%), Gaps = 1/36 (2%)
Frame = +2
Query: 134 IRFYMYELLKALDYCHSKGIMHRDVKPHNVM-IDHQ 168
+R Y+L A+++ H + H D+KP N++ +D Q
Sbjct: 677 VRHISYQLCYAVNFLHENQLTHTDLKPENILFVDSQ 784
>29360
Length = 363
Score = 28.9 bits (63), Expect = 3.5, Method: Compositional matrix adjust.
Identities = 21/59 (35%), Positives = 31/59 (52%), Gaps = 4/59 (6%)
Frame = +3
Query: 111 ALVFEYI--NNTDF--KQLYQILTDFDIRFYMYELLKALDYCHSKGIMHRDVKPHNVMI 165
LVFE + N DF + +Q L IR ++L AL G++H D+KP N+M+
Sbjct: 183 CLVFEMLEQNLYDFLKQNKFQPLPLKYIRPITQQVLTALRKLKQLGLIHADLKPENIML 359
>21210
Length = 518
Score = 27.7 bits (60), Expect = 6.4, Method: Compositional matrix adjust.
Identities = 13/39 (33%), Positives = 20/39 (51%)
Frame = +3
Query: 210 YDYSLDMWSLGCMLASMIFRREPFFHGQDNYDQLVRIAK 248
YD D+WSLG L + R P+ +DQL ++ +
Sbjct: 63 YDVRSDVWSLGITLMELATGRFPYRKWVSIFDQLQQVVR 179
>37603
Length = 1005
Score = 27.7 bits (60), Expect = 6.6, Method: Compositional matrix adjust.
Identities = 10/25 (40%), Positives = 15/25 (60%)
Frame = +2
Query: 139 YELLKALDYCHSKGIMHRDVKPHNV 163
Y + L +CH +GI RD +PH +
Sbjct: 551 YHVRIQLSFCHVEGIKRRDGRPHAI 625
>12045
Length = 1137
Score = 27.7 bits (60), Expect = 8.0, Method: Compositional matrix adjust.
Identities = 17/47 (36%), Positives = 28/47 (59%), Gaps = 1/47 (2%)
Frame = -2
Query: 243 LVRIAKVLGTEELYGYLKKYHIDLDP-HFNDILGQHSRKRWENFIHS 288
++++A+V T +Y Y K H L + ILG ++KR E+F+HS
Sbjct: 302 VIKLARVKNTC-IY*YTKMIHFFLAVFYLPQILGSRTKKRREDFLHS 165
>20152
Length = 445
Score = 27.3 bits (59), Expect = 8.7, Method: Compositional matrix adjust.
Identities = 12/39 (30%), Positives = 21/39 (53%)
Frame = +1
Query: 201 PELLVDYQMYDYSLDMWSLGCMLASMIFRREPFFHGQDN 239
PE+L+ ++D+WSLG +L ++ PF D+
Sbjct: 1 PEILLGDSYDAPAVDVWSLGVILYMLVVGEAPFQEANDS 117
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000300291 | hsapiens_gene_ensembl | Cleavage and
polyadenylation specificity factor 5 (Cleavage and polyadenylation
specificity factor 25 kDa subunit) (CPSF 25 kDa subunit) (Pre-mRNA
cleavage factor Im 25 kDa subunit) (Nucleoside diphosphate-linked
moiety X motif 21) (Nudix motif 21).
[Source:Uniprot/SWISSPROT;Acc:O43809]
(227 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
06241 362 e-101
>06241
Length = 2064
Score = 362 bits (930), Expect = e-101, Method: Compositional matrix adjust.
Identities = 175/229 (76%), Positives = 193/229 (84%), Gaps = 10/229 (4%)
Frame = +2
Query: 8 RSQTGWPR-------GVTQFGNKYIQQTKP---LTLERTINLYPLTNYTFGTKEPLYEKD 57
R Q+GWPR G + + Y T LTLERT+NLYPL+NYTFGTKEPLYE+D
Sbjct: 11 RGQSGWPRDNKGPMSGGSSYSKAYNSSTSSPLNLTLERTVNLYPLSNYTFGTKEPLYERD 190
Query: 58 SSVAARFQRMREEFDKIGMRRTVEGVLIVHEHRLPHVLLLQLGTTFFKLPGGELNPGEDE 117
SSV ARFQRMREEFD++GMRR+VEGVLIVHEH LPHVLLLQLGTTFFKLPGGEL GE++
Sbjct: 191 SSVTARFQRMREEFDRMGMRRSVEGVLIVHEHGLPHVLLLQLGTTFFKLPGGELAAGEEQ 370
Query: 118 VEGLKRLMTEILGRQDGVLQDWVIDDCIGNWWRPNFEPPQYPYIPAHITKPKEHKKLFLV 177
GLKRL+TE LGRQDG +WV++D IGNWWRPNFEPPQYPYIPAHITKPKEHK+LFLV
Sbjct: 371 TAGLKRLLTETLGRQDGAPMNWVVEDTIGNWWRPNFEPPQYPYIPAHITKPKEHKRLFLV 550
Query: 178 QLQEKALFAVPKNYKLVAAPLFELYDNAPGYGPIISSLPQLLSRFNFIY 226
QL EKALFAVP+NYKLVAAPLFELYDN+ GYGPIISSLPQ L RFNFIY
Sbjct: 551 QLPEKALFAVPRNYKLVAAPLFELYDNSAGYGPIISSLPQALGRFNFIY 697
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000366481 | hsapiens_gene_ensembl |
Ubiquitin-activating enzyme E1 (A1S9 protein).
[Source:Uniprot/SWISSPROT;Acc:P22314]
(506 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
34235 225 e-101
25566 200 1e-51
27040 53 3e-07
37747 48 8e-06
>34235
Length = 1026
Score = 225 bits (574), Expect(3) = e-101, Method: Compositional matrix adjust.
Identities = 110/194 (56%), Positives = 133/194 (68%), Gaps = 1/194 (0%)
Frame = -1
Query: 189 FWSGPKRCPHPLTFDVNNPLHLDYVMAAANLFAQTYGLTGSQDRAAVATFLQSVQVPEFT 248
FWSGPKRCPH L FD +N LHLDY+ AAAN+ GL +DRAA+ + V VPEF
Sbjct: 876 FWSGPKRCPHALEFDADNELHLDYIEAAANMKGFMCGLPPVRDRAAIKDMVSKVMVPEFV 697
Query: 249 PKSGVKIHVSDQELQSANA-SVDDSRLEELKATLPSPDKLPGFKMYPIDFEKDDDSNFHM 307
P+SG+KI V+D E Q+ N + D +E+LK+ LPSPD+L G ++ +DFEKDDD+NFHM
Sbjct: 696 PRSGIKIAVTDAEAQAGNNDNFDKDTVEKLKSALPSPDELKGRQLNAVDFEKDDDTNFHM 517
Query: 308 DFIVAASNLRAENYDIPSADRHKSKLXXXXXXXXXXXXXXXVVGLVCLELYKVVQGHRQL 367
DFI AASNLRAENY IP ADRHKSKL VVGLV LEL K+ QGH +
Sbjct: 516 DFITAASNLRAENYSIPPADRHKSKLIAGRIIPAIATTTAMVVGLVGLELIKLAQGHTNV 337
Query: 368 DSYKNGFLNLALPF 381
+ +KNGF NLALP
Sbjct: 336 ERFKNGFANLALPL 295
Score = 124 bits (312), Expect(3) = e-101, Method: Compositional matrix adjust.
Identities = 63/107 (58%), Positives = 81/107 (75%)
Frame = -2
Query: 379 LPFFGFSEPLAAPRHQYYNQEWTLWDRFEVQGLQPNGEEMTLKQFLDYFKTEHKLEITML 438
L F FSEP+ AP+ +YY +E+TLWDRF VQG E+TL+QFLDYF+ EH LEITML
Sbjct: 305 LSLFAFSEPILAPKSKYYEKEFTLWDRFTVQG------EITLQQFLDYFQKEHGLEITML 144
Query: 439 SQGVSMLYSFFMPAAKLKERLDQPMTEIVSRVSKRKLGRHVRALVLE 485
SQGV +L+S FM AK +ER + ++E+V +VSK+K+ HVRALVLE
Sbjct: 143 SQGVCLLFSNFMQPAKQEERKNLLISELVKKVSKKKIPPHVRALVLE 3
Score = 57.4 bits (137), Expect(3) = e-101, Method: Compositional matrix adjust.
Identities = 26/55 (47%), Positives = 37/55 (67%)
Frame = -3
Query: 140 QRSLVLQRPQTWADCVTWACHHWHTQYSNNIRQLLHNFPPDQLTSSGAPFWSGPK 194
+R++ + ++ CV WA + + T YSN I+QLL NFP DQ+TSSGAPF G +
Sbjct: 1024 KRTVNTEFFTSFDKCVEWARNLFQTNYSNQIKQLLFNFPSDQMTSSGAPFLVGSQ 860
>25566
Length = 1639
Score = 200 bits (508), Expect = 1e-51, Method: Compositional matrix adjust.
Identities = 148/438 (33%), Positives = 219/438 (50%), Gaps = 13/438 (2%)
Frame = +2
Query: 79 PFCQL--WPHVICLLCLQWARDEFEGLFKQPAENVNQYLTDPKFVERTLRLAGTQPLEVL 136
P+C + +P I C+QWARD+FE L+ N++L + T + + +V+
Sbjct: 92 PYCTVKSFPATI-EHCIQWARDKFEELYVNQPNLFNKFLASN--ADMTAVVHKLKSGDVV 262
Query: 137 EAVQR--SLVLQRPQTWADCVTWACHHWHTQYSNNIRQLLHNFPPDQLTSSGAPFWSGPK 194
+ R + RP +W DCV A + +++ RQLLH FP D + FW PK
Sbjct: 263 DGGLRVSKMAATRPHSWEDCVRLARIRFEKYFNHKARQLLHAFPLDIKLPDNSLFWQSPK 442
Query: 195 RCPHPLTFDVNNPLHLDYVMAAANLFAQTYGLTGSQDRA--AVATFLQSVQVPEFTPKSG 252
R P PL F+ ++PLH+ +V + A L Y ++ S + ++ T L +V VP F P S
Sbjct: 443 RPPTPLQFNADDPLHMTFVTSTARLLCDIYAISYSTQVSTDSIKTILHAVTVPAFVP-SD 619
Query: 253 VKIHVSDQ------ELQSANASVDDSRLEELKATLPSPDKLPGFKMYPIDFEKDDDSNFH 306
KI + E QS+ V + + + S + M ++FEKDDDSN H
Sbjct: 620 KKIETDETKSQQEAEPQSSGDEVTAAGERLAQVVMSSQAQSALQPMAALEFEKDDDSNDH 799
Query: 307 MDFIVAASNLRAENYDIPSADRHKSKLXXXXXXXXXXXXXXXVVGLVCLELYKVVQGHRQ 366
++FI A SN+RA+ Y I + DR K K V GLV +EL KV+Q R
Sbjct: 800 INFIAACSNMRAQMYSIENVDRLKIKRIAGRIVPAIATTTAAVSGLVTIELIKVLQ-QRP 976
Query: 367 LDSYKNGFLNLALPFFGFSEPLAAPRHQYYNQ-EWTLWDRFEVQGLQPNGEEMTLKQFLD 425
LD++KN FLNLALP SEP A R ++WD++ ++G Q + TL+QFLD
Sbjct: 977 LDAFKNAFLNLALPMLLLSEPGACARKVLKEGLSVSVWDKWTIRGKQ----DFTLQQFLD 1144
Query: 426 YFKTEHKLEITMLSQGVSMLYSFFMPAAKLKERLDQPMTEIVSRVSKRKLGRHVRALVLE 485
K E T + GV ++Y MP K+RL Q M +++ K + + L
Sbjct: 1145SCKDSFGFEATAVVNGVKIIYMPIMPPH--KKRLPQTMMKLI------KPEPGITYVDLV 1300
Query: 486 LCCNDESGEDVEVPYVRY 503
+C D+ GE++E P VRY
Sbjct: 1301VCFEDDKGEEIEGPPVRY 1354
>27040
Length = 385
Score = 52.8 bits (125), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 29/37 (78%), Positives = 29/37 (78%)
Frame = -3
Query: 2 GFHHVGQAGLEPLTSGDPSALASQSAGITGVSYCAWP 38
GFH VGQA LE LTSGDP ASQSAGITGVSY A P
Sbjct: 212 GFHPVGQADLELLTSGDPPTSASQSAGITGVSYRA*P 102
>37747
Length = 505
Score = 48.1 bits (113), Expect = 8e-06, Method: Compositional matrix adjust.
Identities = 24/38 (63%), Positives = 24/38 (63%)
Frame = -1
Query: 1 MGFHHVGQAGLEPLTSGDPSALASQSAGITGVSYCAWP 38
MGF HV QAGLE L S D A Q GI GVS CAWP
Sbjct: 439 MGFRHVAQAGLELLDSSDLPTSAFQCVGIIGVSRCAWP 326
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000376174 | hsapiens_gene_ensembl | GTP-binding
nuclear protein Ran (GTPase Ran) (Ras-like protein TC4) (Androgen
receptor-associated protein 24). [Source:Uniprot/SWISSPROT;Acc:P62826]
(233 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
01972 329 e-101
34359 214 4e-88
08428 83 9e-17
05468 80 5e-16
14456 80 7e-16
17511 78 3e-15
33374 62 8e-15
34468 76 1e-14
13901 74 5e-14
07465 70 5e-13
26083 70 8e-13
11728 69 2e-12
11257 63 8e-11
19006 63 1e-10
07580 55 1e-10
13745 57 5e-09
12339 56 1e-08
30760 56 2e-08
33794 54 4e-08
33380 52 2e-07
35581 50 1e-06
19656 49 2e-06
29380 47 6e-06
01398 46 1e-05
00858 46 1e-05
32723 44 5e-05
26536 44 6e-05
27191 44 7e-05
19046 42 2e-04
31291 41 3e-04
10708 32 0.001
24619 39 0.001
00552 37 0.006
33605 36 0.012
08153 36 0.013
09827 34 0.039
09204 33 0.066
20290 33 0.11
37747 32 0.23
13795 30 1.1
18248 29 1.8
10862 29 1.8
11357 27 5.2
>01972
Length = 2359
Score = 329 bits (844), Expect(2) = e-101, Method: Compositional matrix adjust.
Identities = 157/197 (79%), Positives = 169/197 (85%)
Frame = +3
Query: 37 KKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQEKFGGLRDGYYIQEMGIHHVAHAGLEL 96
KKYVATLGVEVHPL+FHT+RG +KFNVWDTAGQEKFGGLRDGYYIQ
Sbjct: 381 KKYVATLGVEVHPLLFHTSRGKLKFNVWDTAGQEKFGGLRDGYYIQ-------------- 518
Query: 97 MSSAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLCGNKVDIKDRKVKAKSIVFH 156
QCA+IMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLCGNKVDIKDRKVKAK+IVFH
Sbjct: 519 ---GQCAVIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLCGNKVDIKDRKVKAKAIVFH 689
Query: 157 RKKNLQYYDISAKSNYNFEKPFLWLARKLIGDPNLEFVAMPALAPPEVVMDPALAAQYEH 216
RKKNLQYYDISAKSNYNFEKPFLWLARKL+GDPNLEFV MPAL PPEV MD LA +YE
Sbjct: 690 RKKNLQYYDISAKSNYNFEKPFLWLARKLVGDPNLEFVEMPALLPPEVAMDAVLAKKYEE 869
Query: 217 DLEVAQTTALPDEDDDL 233
+L+VAQ ALPD+D+D+
Sbjct: 870 ELKVAQEVALPDDDEDI 920
Score = 55.5 bits (132), Expect(2) = e-101, Method: Compositional matrix adjust.
Identities = 26/32 (81%), Positives = 28/32 (87%)
Frame = +1
Query: 6 EPQVQFKLVLVGDGGTGKTTFVKRHLTGEFEK 37
E + FKLVLVGDGG GKTTFVKRH+TGEFEK
Sbjct: 289 EQEPTFKLVLVGDGGVGKTTFVKRHVTGEFEK 384
>34359
Length = 1042
Score = 214 bits (546), Expect(2) = 4e-88, Method: Compositional matrix adjust.
Identities = 109/153 (71%), Positives = 116/153 (75%)
Frame = +3
Query: 10 QFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQ 69
FKLVLVG VKRH+TG KKYVATLGVEVHPL F+T+RG ++FNVWDTAGQ
Sbjct: 51 NFKLVLVGGRWEWANNIVKRHVTGS*-KKYVATLGVEVHPLQFNTSRGLLRFNVWDTAGQ 227
Query: 70 EKFGGLRDGYYIQEMGIHHVAHAGLELMSSAQCAIIMFDVTSRVTYKNVPNWHRDLVRVC 129
EKFGGLRDGYYIQ CAIIMFDVTSRVTYKNVPNWHRDLVRVC
Sbjct: 228 EKFGGLRDGYYIQ-----------------GTCAIIMFDVTSRVTYKNVPNWHRDLVRVC 356
Query: 130 ENIPIVLCGNKVDIKDRKVKAKSIVFHRKKNLQ 162
ENIPIVLCGNKVDIKDRKVKAK+IVFHRK+
Sbjct: 357 ENIPIVLCGNKVDIKDRKVKAKAIVFHRKRTCS 455
Score = 127 bits (320), Expect(2) = 4e-88, Method: Compositional matrix adjust.
Identities = 58/79 (73%), Positives = 68/79 (86%)
Frame = +2
Query: 155 FHRKKNLQYYDISAKSNYNFEKPFLWLARKLIGDPNLEFVAMPALAPPEVVMDPALAAQY 214
++KNLQYYDISAKSNYNFEKPFLWLARKL+GDPNL FV MPAL PPEV MDP +A +Y
Sbjct: 431 LSQEKNLQYYDISAKSNYNFEKPFLWLARKLVGDPNLXFVEMPALLPPEVAMDPNMAKRY 610
Query: 215 EHDLEVAQTTALPDEDDDL 233
E +L+VAQ ALPD+D+D+
Sbjct: 611 EDELKVAQEVALPDDDEDI 667
>08428
Length = 1109
Score = 83.2 bits (204), Expect = 9e-17, Method: Compositional matrix adjust.
Identities = 53/177 (29%), Positives = 87/177 (49%), Gaps = 3/177 (1%)
Frame = -3
Query: 12 KLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQEK 71
K+ L+GD G GK++ V R +TG + +T+G + +F +WDTAGQEK
Sbjct: 1065 KVCLLGDSGVGKSSIVLRFVTGSYRPSQESTIGASFMSKSLVVDGAGYRFQIWDTAGQEK 886
Query: 72 FGGLRDGYYIQEMGIHHVAHAGLELMSSAQCAIIMFDVTSRVTYKNVPNWHRDLVRVC-E 130
F L YY A A+I++DVT T+K+V +W ++L
Sbjct: 885 FRALAPMYY-----------------RGAAAAVIVYDVTRPRTFKSVKSWIQELRSFGPP 757
Query: 131 NIPIVLCGNKVDIKDRK--VKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKL 185
NI + + GNK D+++ + V+ + + + + + SA + N E+ F LAR+L
Sbjct: 756 NIVLAIAGNKCDLEELREVVEKDAQEYASSISAIFGETSAMTAVNVEEMFTELARQL 586
>05468
Length = 1558
Score = 80.5 bits (197), Expect = 5e-16, Method: Compositional matrix adjust.
Identities = 60/218 (27%), Positives = 105/218 (48%), Gaps = 10/218 (4%)
Frame = -3
Query: 11 FKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGP-IKFNVWDTAGQ 69
+K++++G+ GTGKT+ +KR++ F + Y AT+GV+ V + + I+ +WD AGQ
Sbjct: 1538 YKILVIGELGTGKTSIIKRYVHQFFSQHYRATIGVDFALKVLNWDADTLIRLQLWDIAGQ 1359
Query: 70 EKFGGLRDGYYIQEMGIHHVAHAGLELMSSAQCAIIMFDVTSRVTYKNVPNWHRDL---V 126
E+FG + YY + +G A ++FDVT T+ V W DL V
Sbjct: 1358 ERFGNMTRVYYKEAVG-----------------AFVVFDVTRASTFDAVTKWKNDLDSKV 1230
Query: 127 RVCEN--IPIVLCGNKVD-IKDRKVKAKSIV--FHRKKN-LQYYDISAKSNYNFEKPFLW 180
++ + +P VL NK D K+ V S + F +K + +Y+ SAK N N ++ +
Sbjct: 1229 QLADGSPVPCVLLANKCDQAKEGLVNNTSQMDEFCSEKGFIGWYETSAKENINIDEAARF 1050
Query: 181 LARKLIGDPNLEFVAMPALAPPEVVMDPALAAQYEHDL 218
L +++ + +V+D + E +
Sbjct: 1049 LVTRILEKDRAMQLGDDDRDRDRIVLDKPSSGTQERKI 936
>14456
Length = 1867
Score = 80.1 bits (196), Expect = 7e-16, Method: Compositional matrix adjust.
Identities = 49/175 (28%), Positives = 83/175 (47%), Gaps = 8/175 (4%)
Frame = -1
Query: 19 GGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQEKFGGLRDG 78
GG GK++ + R ++ +F+ + T+GVE + +WDTAGQE+F LR
Sbjct: 1114 GGVGKSSLMNRFVSNKFDAQSFHTIGVEFLNKDVVVDDETYTMQIWDTAGQERFKSLRTP 935
Query: 79 YYIQEMGIHHVAHAGLELMSSAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCE-----NIP 133
+Y A C ++ F V S +++N+ W ++ + + P
Sbjct: 934 FY-----------------RGADCCLLTFSVDSMQSFRNLSMWRKEFLYYADIQDGVTFP 806
Query: 134 IVLCGNKVDIKDRKV---KAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKL 185
V+ GNK+D++ R+V +A+S N Y++ SAK N EK FL ++L
Sbjct: 805 FVVLGNKIDVEGRQVTNEEARSWC-TANSNAPYFETSAKDATNVEKAFLAAVQRL 644
>17511
Length = 483
Score = 78.2 bits (191), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 40/141 (28%), Positives = 72/141 (51%), Gaps = 5/141 (3%)
Frame = -3
Query: 8 QVQFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTA 67
+V K++++GD G GKT+ + +++ +F +Y AT+G + + + +WDTA
Sbjct: 373 KVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTA 194
Query: 68 GQEKFGGLRDGYYIQEMGIHHVAHAGLELMSSAQCAIIMFDVTSRVTYKNVPNWHRDLV- 126
GQE+F L G+ A C +++FDVT T++++ +W + +
Sbjct: 193 GQERFQSL-----------------GVAFYRGADCCVLVFDVTMPNTFRSLDSWRDEFLI 65
Query: 127 ----RVCENIPIVLCGNKVDI 143
R EN P V+ GNK+D+
Sbjct: 64 QASPRDPENFPFVVIGNKIDL 2
>33374
Length = 489
Score = 62.4 bits (150), Expect(2) = 8e-15, Method: Compositional matrix adjust.
Identities = 35/118 (29%), Positives = 61/118 (51%), Gaps = 3/118 (2%)
Frame = +1
Query: 59 IKFNVWDTAGQEKFGGLRDGYYIQEMGIHHVAHAGLELMSSAQCAIIMFDVTSRVTYKNV 118
+KF +WDTAGQE++ L YY AQ AI+++D+T++ T+
Sbjct: 175 VKFEIWDTAGQERYHSLAPMYY-----------------RGAQAAIVVYDITNQDTFGRA 303
Query: 119 PNWHRDLVRVCE-NIPIVLCGNKVDIKDRKVK--AKSIVFHRKKNLQYYDISAKSNYN 173
W ++L R NI I L GNK D+ ++++ ++ + + +L + + SAK+ N
Sbjct: 304 KTWVKELQRQASPNIVIALAGNKADLANKRMVEFEEAQAYAEENSLLFMETSAKTAMN 477
Score = 34.3 bits (77), Expect(2) = 8e-15, Method: Compositional matrix adjust.
Identities = 18/43 (41%), Positives = 28/43 (65%)
Frame = +2
Query: 2 AAQGEPQVQFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLG 44
A QG+ QFKLVL+G+ GK++ V R + G+F + +T+G
Sbjct: 8 ATQGKI-CQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIG 133
>34468
Length = 1502
Score = 75.9 bits (185), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 53/190 (27%), Positives = 91/190 (47%), Gaps = 10/190 (5%)
Frame = +1
Query: 6 EPQVQ---FKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFN 62
E Q Q FK++++GD GKT R G+F K AT+GV+ + +K
Sbjct: 472 EKQTQRRIFKIIVIGDSNVGKTCLTYRFCLGKFPDKTEATIGVDFREKSIQVDSEHLKLQ 651
Query: 63 VWDTAGQEKFGGLRDGYYIQEMGIHHVAHAGLELMSSAQCAIIMFDVTSRVTYKNVPNWH 122
+WDTAGQE+F +Y + +H V + ++D+T +++N+P W
Sbjct: 652 LWDTAGQERFRKSMVQHYYR--NVHAV--------------VFVYDMTKMSSFENMPAWI 783
Query: 123 RDLVR--VCENIPIVLCGNKVDIKDRKVKAKSIV--FHRKKNLQYYDISAKSN---YNFE 175
+ R + + IP +L GNK D+ +R ++ F N+ ++ SAK + + +
Sbjct: 784 EECDRHNLTKYIPRILVGNKCDVVERIAVNTNLAQKFADAHNMPLFETSAKDDEKANHVD 963
Query: 176 KPFLWLARKL 185
F+ +A KL
Sbjct: 964 AIFMTVAHKL 993
>13901
Length = 962
Score = 73.9 bits (180), Expect = 5e-14, Method: Compositional matrix adjust.
Identities = 38/117 (32%), Positives = 60/117 (51%), Gaps = 1/117 (0%)
Frame = -3
Query: 6 EPQVQFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFH-TNRGPIKFNVW 64
+V FK++++GD GKT+FV+R++ F + Y T+GV+ V +++ IK +W
Sbjct: 300 SEEVLFKVIIIGDPTVGKTSFVQRYVNDSFRRDYKMTIGVDFALKVIRWSDKCNIKLQLW 121
Query: 65 DTAGQEKFGGLRDGYYIQEMGIHHVAHAGLELMSSAQCAIIMFDVTSRVTYKNVPNW 121
D AGQE+F + YY A I+MFD+T + TY+N W
Sbjct: 120 DIAGQERFTSMTRVYY-----------------KDAHACIVMFDLTQKNTYQNAIRW 1
>07465
Length = 1103
Score = 70.5 bits (171), Expect = 5e-13, Method: Compositional matrix adjust.
Identities = 44/171 (25%), Positives = 78/171 (45%), Gaps = 4/171 (2%)
Frame = +3
Query: 24 TTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQEKFGGLRDGYYIQE 83
++ ++R+ G F K Y T+GV+ ++ +WDTAGQE+F + YY
Sbjct: 240 SSMIQRYCKGIFTKDYKKTIGVDFLERQIEVGGEDVRLMLWDTAGQEEFDAITKAYY--- 410
Query: 84 MGIHHVAHAGLELMSSAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLCGNKVDI 143
AQ ++ F R +++ + W R + I +V+ NK+D+
Sbjct: 411 --------------RGAQACVLAFSTVDRDSFEALETWKRKVEDEVGEIGMVIVQNKIDL 548
Query: 144 KD----RKVKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLIGDPN 190
D R +A+++ +K L++Y S K N N ++ F +LA K + N
Sbjct: 549 IDDAVVRPEEAENLA--KKLRLRFYRTSVKENMNVDEVFRYLADKYLHQLN 695
>26083
Length = 432
Score = 70.1 bits (170), Expect = 8e-13, Method: Compositional matrix adjust.
Identities = 37/137 (27%), Positives = 65/137 (47%), Gaps = 1/137 (0%)
Frame = +1
Query: 5 GEPQVQFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVW 64
G P +FKLV +G+ GKT+ + R + F+ Y AT+G++ + I+ +W
Sbjct: 61 GNPLRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTIRLQLW 240
Query: 65 DTAGQEKFGGLRDGYYIQEMGIHHVAHAGLELMSSAQCAIIMFDVTSRVTYKNVPNWHRD 124
DTAGQE+F L Y + + A++++D+T+ ++ W D
Sbjct: 241 DTAGQERFRSLIPSY-----------------IRDSSVAVVVYDITNANSFHQTSKWIDD 369
Query: 125 L-VRVCENIPIVLCGNK 140
+ ++ I+L GNK
Sbjct: 370 VRTERGSDVIIMLVGNK 420
>11728
Length = 635
Score = 68.6 bits (166), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 41/138 (29%), Positives = 65/138 (47%), Gaps = 1/138 (0%)
Frame = -1
Query: 11 FKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQE 70
K V+VGDG GKT + + T F +Y+ T+ + + + PI +WDTAGQE
Sbjct: 488 IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTV-FDNYSANVMVDSKPINLGLWDTAGQE 312
Query: 71 KFGGLRDGYYIQEMGIHHVAHAGLELMSSAQCAIIMFDVTSRVTYKNV-PNWHRDLVRVC 129
+ LR Y Q +I F + S +++NV W+ ++ C
Sbjct: 311 DYDRLRPLSYPQ-----------------TDVFLICFSLISPASFENVKAKWYPEVSHHC 183
Query: 130 ENIPIVLCGNKVDIKDRK 147
N PI+L G K+D+++ K
Sbjct: 182 PNTPIILVGTKLDLREDK 129
>11257
Length = 1102
Score = 63.2 bits (152), Expect = 8e-11, Method: Compositional matrix adjust.
Identities = 35/130 (26%), Positives = 64/130 (49%), Gaps = 7/130 (5%)
Frame = -2
Query: 63 VWDTAGQEKFGGLRDGYYIQEMGIHHVAHAGLELMSSAQCAIIMFDVTSRVTYKNVPNWH 122
+WDTAGQE++ LR +Y C ++ F V + + +++ +W+
Sbjct: 1014 IWDTAGQERYKSLRTPFY-----------------RGTDCCLLTFSVDNLKSLQSLSDWY 886
Query: 123 RDLVRVCE-----NIPIVLCGNKVDIKDRKVKAKSIV--FHRKKNLQYYDISAKSNYNFE 175
+ V + + P V+ GNK DI++R+V ++ NL Y++ SAK + N +
Sbjct: 885 DEFVNYADIQDSASFPFVIIGNKADIEEREVSSEDAYNWCRTHGNLPYFETSAKDSLNVQ 706
Query: 176 KPFLWLARKL 185
+ FL + R+L
Sbjct: 705 QAFLAVVRRL 676
>19006
Length = 568
Score = 63.2 bits (152), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 39/135 (28%), Positives = 63/135 (46%), Gaps = 1/135 (0%)
Frame = -2
Query: 12 KLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQEK 71
KLV+VGDG GKT + +F + YV T+ E + + ++ +WDTAGQE
Sbjct: 432 KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTV-FENYVADIEVDSKQVELALWDTAGQED 256
Query: 72 FGGLRDGYYIQEMGIHHVAHAGLELMSSAQCAIIMFDVTSRVTYKNVPN-WHRDLVRVCE 130
+ LR Y ++ F + S + +N+P W ++ C
Sbjct: 255 YDRLRPLSY-----------------PDTDVILMCFSIDSPDSLENIPEKWTPEVRHFCP 127
Query: 131 NIPIVLCGNKVDIKD 145
N+PI+L GNK D+++
Sbjct: 126 NVPIILVGNKKDLRN 82
>07580
Length = 921
Score = 55.1 bits (131), Expect(2) = 1e-10, Method: Compositional matrix adjust.
Identities = 32/129 (24%), Positives = 64/129 (49%), Gaps = 4/129 (3%)
Frame = +3
Query: 61 FNVWDTAGQEKFGGLRDGYYIQEMGIHHVAHAGLELMSSAQCAIIMFDVTSRVTYKNVPN 120
+ DTAG E+F +RD Y M + Q ++ + +T++ T+ ++
Sbjct: 210 LEILDTAGTEQFTAMRDLY-----------------MKNGQGFLLAYSITAQSTFNDLQE 338
Query: 121 WHRDLVRV--CENIPIVLCGNKVDIKDRKV--KAKSIVFHRKKNLQYYDISAKSNYNFEK 176
++RV +++P++L GNK D++D +V K + R + + + SAK+ N +
Sbjct: 339 LREQILRVKDTDDVPMLLVGNKCDLEDERVVGKDQGQGLARSFSCAFLETSAKARINVNE 518
Query: 177 PFLWLARKL 185
F+ L R++
Sbjct: 519 IFMDLVRQI 545
Score = 27.3 bits (59), Expect(2) = 1e-10, Method: Compositional matrix adjust.
Identities = 12/33 (36%), Positives = 20/33 (60%)
Frame = +2
Query: 6 EPQVQFKLVLVGDGGTGKTTFVKRHLTGEFEKK 38
E ++KLV++G GG GK+ + + G+F K
Sbjct: 47 ETMREYKLVVLGSGGVGKSALTVQFVQGDFCGK 145
>13745
Length = 1045
Score = 57.4 bits (137), Expect = 5e-09, Method: Compositional matrix adjust.
Identities = 30/101 (29%), Positives = 54/101 (53%), Gaps = 7/101 (6%)
Frame = +2
Query: 93 GLELMSSAQCAIIMFDVTSRVTYKNVPNWHRDLV-----RVCENIPIVLCGNKVDIKDRK 147
G+ A C ++++DVT+ ++KN+ +W + + R E+ P V+ GNKVD+ +R+
Sbjct: 23 GVAFYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPEHFPFVVLGNKVDLDNRQ 202
Query: 148 VKAKSIV--FHRKKNLQYYDISAKSNYNFEKPFLWLARKLI 186
V + K ++ YY+ SAK N E F +A+ +
Sbjct: 203 VSTRRAQQWCQSKNDIPYYETSAKEGINVEMAFQTIAKNAL 325
>12339
Length = 578
Score = 55.8 bits (133), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 31/102 (30%), Positives = 53/102 (51%), Gaps = 7/102 (6%)
Frame = -2
Query: 93 GLELMSSAQCAIIMFDVTSRVTYKNVPNWHRDLV-----RVCENIPIVLCGNKVDIKDRK 147
G+ A C I+++DVT T+ ++ +W R+ + R E+ P V+ GNK+D+ +R
Sbjct: 556 GVAFYRGADCCILVYDVTEXKTFDSLDSWQREFLNQASPRDPEHFPFVVIGNKIDLDNRV 377
Query: 148 VKAK--SIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLIG 187
V AK K + Y++ SAK N E+ F +A+ +
Sbjct: 376 VTAKRGQGWCSTKGGIPYFETSAKEAINVEQAFQTVAKNALA 251
>30760
Length = 596
Score = 55.8 bits (133), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 44/179 (24%), Positives = 79/179 (44%), Gaps = 8/179 (4%)
Frame = -1
Query: 12 KLVLVGDGGTGKTTFVK--RHLTGEFEKKYVATLGVEVHPLVFHT--NRGPIKFNVWDTA 67
K ++ GD G GK++ + + F K Y T GVEV + + +R ++ ++D+A
Sbjct: 524 KCIVTGDSGVGKSSICQVFHSDSAHFPKNYSMTTGVEVLVKLVNIPDSRDQVELYLFDSA 345
Query: 68 GQEKFGGLRDGYYIQEMGIHHVAHAGLELMSSAQCAIIMFDVTSRVTYKNVPNWHRDLVR 127
G+E F ++ Q + ++++DVT ++ W +
Sbjct: 344 GKEIFSENVTKFWDQPSVV-----------------MVVYDVTDETSFSGCVRWLERVRA 216
Query: 128 VCEN--IPIVLCGNKVDIKDRK--VKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLA 182
N IP VL NK D+ +R+ + + + L+Y++ SAK N + PF LA
Sbjct: 215 AKPNTVIPGVLVANKTDLDERRRVSRKEGKDLAQSHGLEYFECSAKEMQNTDTPFFCLA 39
>33794
Length = 779
Score = 54.3 bits (129), Expect = 4e-08, Method: Compositional matrix adjust.
Identities = 33/138 (23%), Positives = 65/138 (47%), Gaps = 2/138 (1%)
Frame = -1
Query: 59 IKFNVWDTAGQEKFGGLRDGYYIQEMGIHHVAHAGLELMSSAQCAIIMFDVTSRVTYKNV 118
+K +WDT+GQ +F + Y GI I+++D+T++ ++ +
Sbjct: 650 VKLQIWDTSGQGRFCTIIRSYSRGAQGI-----------------ILVYDITNKWSFDGI 522
Query: 119 PNWHRDLVRVCENIPIVLCGNKVDIK-DRKVKAKSI-VFHRKKNLQYYDISAKSNYNFEK 176
W +++ IP VL GN++ + R+V AK + + N+ ++IS ++N +
Sbjct: 521 DRWLKEVEEHAPGIPKVLVGNRLHLAYKRQVAAKQAETYASRNNMSCFEISPLCDFNIRE 342
Query: 177 PFLWLARKLIGDPNLEFV 194
F LAR + +E +
Sbjct: 341 SFCELARMALHRNGMEHI 288
>33380
Length = 282
Score = 52.4 bits (124), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 30/99 (30%), Positives = 49/99 (49%), Gaps = 1/99 (1%)
Frame = +3
Query: 51 VFHTNRGPIKFNVWDTAGQEKFGGLRDGYYIQEMGIHHVAHAGLELMSSAQCAIIMFDVT 110
VF ++ +K +WDTAGQE++ + YY MG I+M+DVT
Sbjct: 39 VFRQDK-RVKLQIWDTAGQERYRTITTAYYRGAMGF-----------------ILMYDVT 164
Query: 111 SRVTYKNVPNWHRDL-VRVCENIPIVLCGNKVDIKDRKV 148
+ ++ V +W + +N +VL GNK D++D +V
Sbjct: 165 NEESFNAVQDWCTQIKTYSWDNAQVVLVGNKCDLEDERV 281
>35581
Length = 364
Score = 49.7 bits (117), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 26/77 (33%), Positives = 37/77 (48%), Gaps = 1/77 (1%)
Frame = +2
Query: 5 GEPQVQFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPI-KFNV 63
G + FK VL+GD G GKT + R T +F + +L G + ++
Sbjct: 29 GNDTLYFKCVLLGDAGVGKTCLLNRLATDKFLDSPLTSLTTASLLTTVTLTSGVMASVDL 208
Query: 64 WDTAGQEKFGGLRDGYY 80
WDTAGQE++ L YY
Sbjct: 209 WDTAGQERYRSLTSSYY 259
>19656
Length = 428
Score = 48.9 bits (115), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 27/71 (38%), Positives = 36/71 (50%)
Frame = +3
Query: 12 KLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQEK 71
K V+VGDG GKT + + T F +Y+ T+ V R P+ +WDTAGQE
Sbjct: 117 KCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGR-PVNLGLWDTAGQED 293
Query: 72 FGGLRDGYYIQ 82
+ LR Y Q
Sbjct: 294 YDRLRPLSYPQ 326
>29380
Length = 853
Score = 47.0 bits (110), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 32/93 (34%), Positives = 52/93 (55%), Gaps = 6/93 (6%)
Frame = -2
Query: 100 AQCAIIMFDVTSRVTYKNVPNWHRDLVRV-CENIPIVLCGNKVDI--KDRKVK---AKSI 153
A AII++DV T+ W ++L + E++ I+L GNKVD+ + R V A+S
Sbjct: 852 ASAAIIVYDVNIADTFSRALAWVKELRQQNTESVLIILAGNKVDLATQHRAVSFEDAQS- 676
Query: 154 VFHRKKNLQYYDISAKSNYNFEKPFLWLARKLI 186
F R+ L + ++SAK+ + F+ LA +LI
Sbjct: 675 -FARENGLLFAEVSAKTGMAVNEIFMTLANQLI 580
>01398
Length = 1421
Score = 46.2 bits (108), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 35/120 (29%), Positives = 61/120 (50%), Gaps = 5/120 (4%)
Frame = -2
Query: 69 QEKFGGLRDGYYIQEMGIHHVAHAGLELMSSAQCAIIMFDVTSRVTYKNVPNWH---RDL 125
QE+F + YY +G+ II++D+T R T++N+ W+ R+
Sbjct: 1420 QERFRSITRSYYRNSVGV-----------------IIVYDITKRSTFENLKQWYEEARNH 1292
Query: 126 VRVCENIPIVLCGNKVDIKD-RKVKAKS-IVFHRKKNLQYYDISAKSNYNFEKPFLWLAR 183
+ + I +VL G+K D +D R+V A+ F L++++ SAKS +N E F +A+
Sbjct: 1291 IEPHKAIFLVL-GHKSDREDARQVTAREGRRFAEMHGLKFFETSAKSGHNIEDVFAQIAK 1115
>00858
Length = 1658
Score = 45.8 bits (107), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 31/132 (23%), Positives = 63/132 (47%), Gaps = 7/132 (5%)
Frame = -2
Query: 61 FNVWDTAGQEKFGGLRDGYYIQEMGIHHVAHAGLELMSSAQCAIIMFDVTSRVTYKNVPN 120
++ DTAGQE+ +RD + M + + + +F V + +++++
Sbjct: 1441 LDILDTAGQEEXSAMRD-----------------QCMRTGEGFLCVFAVXNLKSFEDINQ 1313
Query: 121 WHRDLVRV--CENIPIVLCGNKVDIKDRKVKAK-----SIVFHRKKNLQYYDISAKSNYN 173
+ + RV + +P+VL GNKVD+ R V+ + + ++H + Y + SAK+
Sbjct: 1312 YREQIKRVKDADEVPMVLVGNKVDLPIRNVEQRQGKHMAELYH----IPYVETSAKTRQG 1145
Query: 174 FEKPFLWLARKL 185
+ F L R++
Sbjct: 1144 VDDAFYTLVREI 1109
>32723
Length = 384
Score = 44.3 bits (103), Expect = 5e-05, Method: Compositional matrix adjust.
Identities = 32/125 (25%), Positives = 54/125 (43%), Gaps = 3/125 (2%)
Frame = +2
Query: 69 QEKFGGLRDGYYIQEMGIHHVAHAGLELMSSAQCAIIMFDVTSRVTYKNVPNW-HRDLVR 127
QE+F + YY SA I+++DV S+ +Y+++P W H +
Sbjct: 2 QERFRSITQSYY-----------------RSANALILVYDVCSQQSYESLPQWIHEIELY 130
Query: 128 VCENIPIVLCGNKVDIKDRKVKAKSI--VFHRKKNLQYYDISAKSNYNFEKPFLWLARKL 185
+ L GNK+D D++ I F + +++ + SAK N EK F +A +L
Sbjct: 131 AGTKVLAFLVGNKIDQTDKREIPTHIGKEFAERYEMRFLETSAKEADNVEKLFSTIAYQL 310
Query: 186 IGDPN 190
Sbjct: 311 TAQAQ 325
>26536
Length = 829
Score = 43.9 bits (102), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 34/131 (25%), Positives = 57/131 (43%), Gaps = 4/131 (3%)
Frame = +2
Query: 59 IKFNVWDTAGQEKFGGLRDGYYIQEMGIHHVAHAGLELMSSAQCAIIMFDVTSRVTYKNV 118
+ + DTAGQE++ +R+ Y S I+++ VT +++
Sbjct: 128 VSWTFLDTAGQEEYSSMREHY-----------------TRSGDGFIVVYSVTDVTSFQEA 256
Query: 119 PNWHRDLVRVCENIPI--VLCGNKVDI-KDRKVK-AKSIVFHRKKNLQYYDISAKSNYNF 174
R L R + I VLCGNK D+ DRKV + + + Y++ SAK+ N
Sbjct: 257 EAVFRWLTRFQDETSIHAVLCGNKTDLTSDRKVTPEEGRKMADRLGMLYFETSAKTGDNV 436
Query: 175 EKPFLWLARKL 185
+ + L R +
Sbjct: 437 SQVYHGLLRSI 469
>27191
Length = 443
Score = 43.5 bits (101), Expect = 7e-05, Method: Compositional matrix adjust.
Identities = 27/120 (22%), Positives = 57/120 (47%), Gaps = 1/120 (0%)
Frame = +1
Query: 23 KTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQEKFGGLRDGYYIQ 82
KT +K +F + Y T+GV+ + N ++ ++WD +G ++ +R+
Sbjct: 1 KTCLIKHFCESKFNQGYQPTVGVDYGFKIQTVNGVDMRVHMWDLSGSNEYLDVRN----- 165
Query: 83 EMGIHHVAHAGLELMSSAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPI-VLCGNKV 141
EL + + I+FDV++ +++ + +W R++ R P+ V+ GN+V
Sbjct: 166 ------------ELYTGSDAIFIVFDVSNTPSFEALDSWLREINRFATGSPLNVIVGNRV 309
>19046
Length = 445
Score = 42.0 bits (97), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 28/105 (26%), Positives = 51/105 (48%), Gaps = 4/105 (3%)
Frame = -2
Query: 69 QEKFGGLRDGYYIQEMGIHHVAHAGLELMSSAQCAIIMFDVTSRVTYKNVPNWHRDLVRV 128
QE+F +R+ Y M +++F VT +++N+ N+H ++RV
Sbjct: 444 QEEFSAMREQY-----------------MRKGDGFLLVFSVTDFRSFENMANFHTQILRV 316
Query: 129 --CENIPIVLCGNKVD-IKDRKVKAKSIV-FHRKKNLQYYDISAK 169
++ P++LC NKVD + RKV + + + + Y + SAK
Sbjct: 315 KDRDSYPMILCANKVDLVHQRKVSEEQVRDLATRLRIPYIETSAK 181
>31291
Length = 446
Score = 41.2 bits (95), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 31/134 (23%), Positives = 55/134 (41%), Gaps = 16/134 (11%)
Frame = -1
Query: 61 FNVWDTAGQEKFGGLRDGYYIQEMGIHHVAHAGLELMSSAQCAIIMFDVTSRVTYKNVP- 119
+WDTAGQE + LR Y + ++ F + S + KNV
Sbjct: 446 LQLWDTAGQEDYDRLRPLAY-----------------PNTDVFMLXFSLMSEASMKNVKV 318
Query: 120 NWHRDLVRVCENIPIVLCGNKVDIKDRKVKAKSIVFHRK---------------KNLQYY 164
W+ ++ ++PIVL G K+D++ K + + R+ K +Y+
Sbjct: 317 KWYPEIRHHDPHVPIVLVGTKLDLRQDKEAVRKLRSSRQDPVSSNQGNDLAKAIKAKRYF 138
Query: 165 DISAKSNYNFEKPF 178
+ S+K+ N + F
Sbjct: 137 ECSSKTQENLKTAF 96
>10708
Length = 2775
Score = 31.6 bits (70), Expect(2) = 0.001, Method: Compositional matrix adjust.
Identities = 15/47 (31%), Positives = 28/47 (59%)
Frame = -3
Query: 99 SAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLCGNKVDIKD 145
S+ CA + +T+ T ++ W ++ C N+PI+L GNK D+++
Sbjct: 2644 SSLCASPLTALTAWRT--SLKKWTPEVRHFCPNVPIILVGNKKDLRN 2510
Score = 26.9 bits (58), Expect(2) = 0.001, Method: Compositional matrix adjust.
Identities = 9/18 (50%), Positives = 13/18 (72%)
Frame = -2
Query: 59 IKFNVWDTAGQEKFGGLR 76
++ +WDTAGQE + LR
Sbjct: 2723 VELALWDTAGQEDYDRLR 2670
>24619
Length = 509
Score = 39.3 bits (90), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 31/126 (24%), Positives = 56/126 (44%), Gaps = 5/126 (3%)
Frame = -2
Query: 69 QEKFGGLRDGYYIQEMGIHHVAHAGLELMSSAQCAIIMFDVTSRVTYKNVPNWHRDLVRV 128
QE+F +R+ Y M +++F V +++N+ N+H ++RV
Sbjct: 508 QEEFSAMREQY-----------------MRKGDGFLLVFSVIDYQSFENMVNFHTQILRV 380
Query: 129 --CENIPIVLCGNKVD-IKDRKVKAKSIV-FHRKKNLQYYDISAKS-NYNFEKPFLWLAR 183
+ P++LC NKVD + RKV + + + + Y + SAK N + F + R
Sbjct: 379 KDRDTYPMILCANKVDLVHQRKVSEEQVRDLATRLRIPYIETSAKDPPLNVDLAFHQVVR 200
Query: 184 KLIGDP 189
+ P
Sbjct: 199 VIRAQP 182
>00552
Length = 455
Score = 37.0 bits (84), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 15/36 (41%), Positives = 26/36 (72%)
Frame = -1
Query: 11 FKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVE 46
K+VL+GDGG GK++ + R ++ +F+ + T+GVE
Sbjct: 443 LKVVLLGDGGVGKSSLMNRFVSNKFDAQSFHTIGVE 336
Score = 32.7 bits (73), Expect = 0.14, Method: Compositional matrix adjust.
Identities = 15/64 (23%), Positives = 29/64 (45%)
Frame = -3
Query: 63 VWDTAGQEKFGGLRDGYYIQEMGIHHVAHAGLELMSSAQCAIIMFDVTSRVTYKNVPNWH 122
+WDTAGQE++ LR +Y C ++ F V + + +++ +W+
Sbjct: 147 IWDTAGQERYKSLRTPFY-----------------RGTDCCLLTFSVDNLKSLQSLSDWY 19
Query: 123 RDLV 126
+ V
Sbjct: 18 DEFV 7
>33605
Length = 888
Score = 36.2 bits (82), Expect = 0.012, Method: Compositional matrix adjust.
Identities = 28/97 (28%), Positives = 44/97 (45%)
Frame = +1
Query: 6 EPQVQFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWD 65
+ + + +L+++G GKTT +K+ GE TLG + L +RG K NVWD
Sbjct: 484 QKEKEVRLLMLGLDNAGKTTILKK-FNGEDIDTISPTLGFNIKTL---EHRG-FKLNVWD 648
Query: 66 TAGQEKFGGLRDGYYIQEMGIHHVAHAGLELMSSAQC 102
GQ+ Y+ G+ V + + M A C
Sbjct: 649 VGGQQSLRSYWRNYFESTDGLVWVVDSA-DRMRIADC 756
>08153
Length = 1703
Score = 35.8 bits (81), Expect = 0.013, Method: Compositional matrix adjust.
Identities = 23/83 (27%), Positives = 38/83 (45%)
Frame = +1
Query: 10 QFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQ 69
+ ++++VG GKTT + + GE + T+G V + + I F VWD GQ
Sbjct: 82 EVRILMVGLDAAGKTTILYKLKLGEIVTT-IPTIGFNVETVEYKN----ISFTVWDVGGQ 246
Query: 70 EKFGGLRDGYYIQEMGIHHVAHA 92
+K L Y+ G+ V +
Sbjct: 247 DKIRPLWRHYFQNTQGLIFVVDS 315
>09827
Length = 1201
Score = 34.3 bits (77), Expect = 0.039, Method: Compositional matrix adjust.
Identities = 23/82 (28%), Positives = 37/82 (45%)
Frame = -3
Query: 11 FKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQE 70
++++VG GKTT + + GE + T+G V + + I F VWD GQ+
Sbjct: 1112 MRILMVGLDAAGKTTILYKLKLGEIVTT-IPTIGFNVETVEYKN----ISFTVWDVGGQD 948
Query: 71 KFGGLRDGYYIQEMGIHHVAHA 92
K L Y+ G+ V +
Sbjct: 947 KIRPLWRHYFQNTQGLIFVVDS 882
>09204
Length = 1051
Score = 33.5 bits (75), Expect = 0.066, Method: Compositional matrix adjust.
Identities = 22/89 (24%), Positives = 44/89 (49%), Gaps = 6/89 (6%)
Frame = -3
Query: 100 AQCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLCGNKVDI----KDRKVKAKSIVF 155
A+ AI+ FD+T + ++ + W +L + E + +CG K D+ +R+ +S+
Sbjct: 1013 AKAAILCFDLTDKSSFDRIRFWIGELRQHEEECKLYICGTKFDLVHDDPERRAVPRSVAK 834
Query: 156 HRKKNL--QYYDISAKSNYNFEKPFLWLA 182
+ + Y+ S+ + N EK F +A
Sbjct: 833 ALADDCMAEIYETSSMTGDNIEKLFTKIA 747
>20290
Length = 1550
Score = 33.1 bits (74), Expect = 0.11, Method: Compositional matrix adjust.
Identities = 19/46 (41%), Positives = 26/46 (56%), Gaps = 3/46 (6%)
Frame = +1
Query: 13 LVLVGDGGTGKTTFVKRHLTGEFE---KKYVATLGVEVHPLVFHTN 55
LVL+G+ GTGKTTF+ R L G + + + L + P FH N
Sbjct: 787 LVLLGENGTGKTTFI-RMLAGNLQPDGEVELPMLNISYKPQKFHRN 921
>37747
Length = 505
Score = 32.0 bits (71), Expect = 0.23, Method: Compositional matrix adjust.
Identities = 13/22 (59%), Positives = 16/22 (72%)
Frame = -1
Query: 79 YYIQEMGIHHVAHAGLELMSSA 100
Y+ EMG HVA AGLEL+ S+
Sbjct: 454 YFFVEMGFRHVAQAGLELLDSS 389
>13795
Length = 642
Score = 29.6 bits (65), Expect = 1.1, Method: Compositional matrix adjust.
Identities = 17/33 (51%), Positives = 20/33 (60%), Gaps = 1/33 (3%)
Frame = -1
Query: 1 MAAQGEPQVQFK-LVLVGDGGTGKTTFVKRHLT 32
M A E Q Q K L ++GDGGT T+FV LT
Sbjct: 204 MTAGSEVQAQAKRLQILGDGGTQPTSFVNSVLT 106
>18248
Length = 466
Score = 28.9 bits (63), Expect = 1.8, Method: Compositional matrix adjust.
Identities = 13/24 (54%), Positives = 19/24 (79%)
Frame = +3
Query: 13 LVLVGDGGTGKTTFVKRHLTGEFE 36
+V++G+ GTGKTTF+K L G+ E
Sbjct: 108 IVMLGENGTGKTTFIKM-LAGKLE 176
>10862
Length = 2896
Score = 28.9 bits (63), Expect = 1.8, Method: Compositional matrix adjust.
Identities = 12/27 (44%), Positives = 15/27 (55%)
Frame = -3
Query: 60 KFNVWDTAGQEKFGGLRDGYYIQEMGI 86
+FNVWD GQ+K L YY G+
Sbjct: 2483 QFNVWDVGGQDKIRPLWRHYYTGTQGL 2403
>11357
Length = 1307
Score = 27.3 bits (59), Expect = 5.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 27/42 (64%), Gaps = 4/42 (9%)
Frame = -2
Query: 162 QYYDISA---KSNYNFEKPFLWLAR-KLIGDPNLEFVAMPAL 199
++YD S+ K+NY+F+K F+W + +L +LE++ + L
Sbjct: 733 EHYDFSSCISKNNYSFKKGFIWFSCIQLFKRGSLEYMLVFVL 608
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000300093 | hsapiens_gene_ensembl |
Serine/threonine-protein kinase PLK1 (EC 2.7.11.21) (Polo-like kinase
1) (PLK-1) (Serine/threonine-protein kinase 13) (STPK13).
[Source:Uniprot/SWISSPROT;Acc:P53350]
(603 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
12185 360 e-100
18484 113 2e-25
18921 111 9e-25
30881 109 4e-24
30755 109 4e-24
00300 108 4e-24
15910 108 8e-24
03240 105 5e-23
12721 103 3e-22
13212 99 3e-21
13592 96 4e-20
14420 87 2e-17
26560 86 4e-17
19094 85 8e-17
09606 84 1e-16
21433 84 2e-16
25019 57 4e-16
01392 80 2e-15
00486 80 3e-15
21079 80 3e-15
31885 80 3e-15
01060 76 5e-14
19761 74 1e-13
29581 73 4e-13
01707 72 5e-13
38560 71 1e-12
14126 71 1e-12
12786 70 2e-12
00392 70 3e-12
26711 70 3e-12
01756 69 4e-12
18663 69 5e-12
04852 67 1e-11
04138 67 2e-11
01718 67 2e-11
20152 66 4e-11
13066 65 1e-10
27405 65 1e-10
07940 64 2e-10
04591 62 6e-10
06405 61 1e-09
21808 60 3e-09
02638 59 8e-09
14116 58 1e-08
01966 57 2e-08
00715 57 3e-08
27546 56 4e-08
07291 55 6e-08
09007 55 8e-08
17300 55 9e-08
11185 54 2e-07
12672 52 7e-07
32957 52 9e-07
03508 51 1e-06
29590 50 2e-06
20640 50 2e-06
28638 49 5e-06
19301 49 5e-06
18401 49 6e-06
14477 49 7e-06
31489 42 7e-06
11780 49 8e-06
37602 49 8e-06
31120 44 2e-04
17975 43 4e-04
28157 41 0.001
18996 41 0.002
17516 40 0.002
07836 36 0.052
17253 36 0.057
26009 35 0.068
32000 35 0.071
13078 35 0.084
16708 35 0.099
27274 34 0.15
17722 34 0.22
03106 32 1.1
16350 31 1.8
23319 30 3.0
29722 29 4.7
>12185
Length = 869
Score = 360 bits (924), Expect = e-100, Method: Compositional matrix adjust.
Identities = 164/223 (73%), Positives = 200/223 (89%)
Frame = +3
Query: 381 LHSVNASKPSERGLVRQEEAEDPACIPIFWVSKWVDYSDKYGLGYQLCDNSVGVLFNDST 440
L SV ASKPSER + +EAEDPACIPI+WVSKWVDYSDKYGLGYQLCDNSVGVLFNDS+
Sbjct: 33 LSSVVASKPSERLTTQIDEAEDPACIPIYWVSKWVDYSDKYGLGYQLCDNSVGVLFNDSS 212
Query: 441 RLILYNDGDSLQYIERDGTESYLTVSSHPNSLMKKITLLKYFRNYMSEHLLKAGANITPR 500
RL+L +G+++ YIERDG E Y T+ +P +L KK+TLLKYFRNYM+EHLLKAGAN+TPR
Sbjct: 213 RLLLLANGENIHYIERDGQEHYHTLKVYPEALNKKVTLLKYFRNYMNEHLLKAGANMTPR 392
Query: 501 EGDELARLPYLRTWFRTRSAIILHLSNGSVQINFFQDHTKLILCPLMAAVTYIDEKRDFR 560
+ DE+ RLP+LRTWFRTRSAI+LHLSNG++QINFFQDHTK+ILCPLMAA TYIDEKR+F
Sbjct: 393 DTDEMMRLPFLRTWFRTRSAIVLHLSNGTLQINFFQDHTKVILCPLMAAATYIDEKREFH 572
Query: 561 TYRLSLLEEYGCCKELASRLRYARTMVDKLLSSRSASNRLKAS 603
T+R++L+E+YGC K+LASR+RYARTMV++LLSS+S S R+K++
Sbjct: 573 TFRMNLIEKYGCSKDLASRVRYARTMVERLLSSKSGSGRVKSA 701
>18484
Length = 635
Score = 113 bits (282), Expect = 2e-25, Method: Compositional matrix adjust.
Identities = 53/151 (35%), Positives = 87/151 (57%)
Frame = +1
Query: 143 KRRKALTEPEARYYLRQIVLGCQYLHRNRVIHRDLKLGNLFLNEDLEVKIGDFGLATKVE 202
++ EP A +Y +I +G +LH +I+RDLKL N+ L+ + +KI DFG+ +
Sbjct: 19 QQEGKFKEPVAAFYAAEIAVGLFFLHDQGIIYRDLKLDNVMLDSEGHIKIADFGMCKEGM 198
Query: 203 YDGERKKTLCGTPNYIAPEVLSKKGHSFEVDVWSIGCIMYTLLVGKPPFETSCLKETYLR 262
+T CGTP+YIAPE++ + +S VD W+ G +++ +L G+PPF+ E +
Sbjct: 199 TGDATTRTFCGTPDYIAPEIVLYQPYSKSVDWWAYGVLLFEMLAGQPPFDGEDEDELFSS 378
Query: 263 IKKNEYSIPKHINPVAASLIQKMLQTDPTAR 293
I + S PK ++ A SL + +L +PT R
Sbjct: 379 ITDHNVSYPKAMSREAVSLCKGLLMKNPTKR 471
>18921
Length = 697
Score = 111 bits (277), Expect = 9e-25, Method: Compositional matrix adjust.
Identities = 66/200 (33%), Positives = 103/200 (51%), Gaps = 2/200 (1%)
Frame = +2
Query: 59 LGKGGFAKCFEISDADTKEVFAGKIVPKSLLLKPHQREKMSMEISIHRSLAHQHVVGFHG 118
LG+G + F+ +T +V A K VP L +++ EISI + +++V ++G
Sbjct: 53 LGEGSYGSVFKSLHKETGQVLAIKQVPVDTDL-----QEIIKEISIMQQCDSKYIVKYYG 217
Query: 119 -FFEDNDFVFVVXXXXXXXXXXXXHKRRKALTEPEARYYLRQIVLGCQYLHRNRVIHRDL 177
+F++ D V+ R K L E E L + G YLH R IHRD+
Sbjct: 218 SYFKNTDLWIVMEYCGAGSVSDIMRLRNKTLVEREIATILYYTLKGLXYLHSRRKIHRDI 397
Query: 178 KLGNLFLNEDLEVKIGDFGLATKVEYDGERKKTLCGTPNYIAPEVLSKKGHSFEVDVWSI 237
K GN+ LN + K+ DFG+A ++ ++ T+ GTP ++APEV+ + G+ D+WS+
Sbjct: 398 KAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTPYWMAPEVIQEIGYDCVADIWSL 577
Query: 238 GCIMYTLLVGKPP-FETSCL 256
G + GKPP ETS L
Sbjct: 578 GITALEMAEGKPPVMETSIL 637
>30881
Length = 529
Score = 109 bits (272), Expect = 4e-24, Method: Compositional matrix adjust.
Identities = 59/145 (40%), Positives = 90/145 (62%), Gaps = 5/145 (3%)
Frame = +1
Query: 457 DGTESYL--TVSSHPNSLMKKITLLKYFRNYMSEHLLKAGANITPREGDELARLP-YLRT 513
D TE + T+ S P L +K TLL+YF YM EHL++ G + + G+ P YL+
Sbjct: 16 DMTEKLMEYTLDSVPEDLSRKTTLLQYFTRYMDEHLIQGGDLESSQPGEAAWLSPLYLKK 195
Query: 514 WFRTRSAIILHLSNGSVQINFFQDHTKLILCPLMA--AVTYIDEKRDFRTYRLSLLEEYG 571
WFRT AI+L+L++G++Q+NFF DH KLIL + +T+ID +R +TY L+L+ ++G
Sbjct: 196 WFRTTKAIVLYLTDGTLQVNFFDDHAKLILSRVKDDYLMTFIDPERCAKTYSLALIAQHG 375
Query: 572 CCKELASRLRYARTMVDKLLSSRSA 596
C E+ R+ +A TM+ L+ A
Sbjct: 376 CQGEIMRRMTFAHTMLTNLVDIEGA 450
>30755
Length = 1137
Score = 109 bits (272), Expect = 4e-24, Method: Compositional matrix adjust.
Identities = 59/168 (35%), Positives = 84/168 (50%), Gaps = 5/168 (2%)
Frame = +2
Query: 145 RKALTEPEARYYLRQIVLGCQYLHRNRVIHRDLKLGNLFLNEDLEVKIGDFGLATKVEYD 204
+ TE R+Y +I+ YLH +I+RDLKL NL L++D +K+ DFGL +
Sbjct: 14 ERIFTEERTRFYGAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCKEDITY 193
Query: 205 GERKKTLCGTPNYIAPEVLSKKGHSFEVDVWSIGCIMYTLLVGKPPFETSCLKETYLRIK 264
G KT CGTP Y+APEVL + VD W G +MY ++ G+ PF + I
Sbjct: 194 GRTTKTFCGTPEYLAPEVLDDNDYGRAVDWWGTGVVMYEMICGRLPFYNRDHDVLFTLIL 373
Query: 265 KNEYSIPKHINPVAASLIQKMLQTDPTAR-----PTINELLNDEFFTS 307
+ P++I A SL+ +L DP R + E+ FF S
Sbjct: 374 VEDVKFPRNITDEAKSLLSGLLAKDPRNRLGGGQDDVKEIQAHPFFAS 517
>00300
Length = 2318
Score = 108 bits (271), Expect = 4e-24, Method: Compositional matrix adjust.
Identities = 80/272 (29%), Positives = 128/272 (47%), Gaps = 14/272 (5%)
Frame = -1
Query: 52 RYVRGRFLGKGGFAKCFEISDADTKEVFA---GKIVPKSLLLKPHQREKMSMEISIHRSL 108
R+ RG +G+G F K + + T E+ A K P L Q +M EI I +
Sbjct: 1655 RWQRGNKIGEGQFGKVYTAVNMSTGELMALKEMKFQPNDL----QQLREMCDEIKIFEGI 1488
Query: 109 AHQHVVGFHGFFEDNDFVFVVXXXXXXXXXXXXHKRRKALTEPEARYYLRQIVLGCQYLH 168
H+++V ++G D + + K L E R Y R+IVL +LH
Sbjct: 1487 QHENLVKYYGVEVHKDEMLMFMEYCDTGTIEEAAK--MGLPEYLIRRYTREIVLAVNHLH 1314
Query: 169 RNRVIHRDLKLGNLFLNEDLEVKIGDFGLATKVEYD----GERKKTLCGTPNYIAPEVLS 224
N ++HRD+K N+FL + VK+GDFG + K++ GE L GT Y+APEV +
Sbjct: 1313 ENSIVHRDIKGANIFLTSNGHVKLGDFGCSVKLKSHTTMPGEF-HNLVGTTAYMAPEVFT 1137
Query: 225 KK---GHSFEVDVWSIGCIMYTLLVGKPPFETSCLKETYLRIKK----NEYSIPKHINPV 277
+ G+ D+WS+GC++ + GK P+ L Y + K ++ ++P ++
Sbjct: 1136 QNDQGGYGRAADIWSLGCVVIEMATGKRPWHD--LDNNYQIMYKVGIGHKPAVPDSLSVE 963
Query: 278 AASLIQKMLQTDPTARPTINELLNDEFFTSGY 309
+ ++ DP R ++LL D FT Y
Sbjct: 962 GKHFLDLIMCHDPAQRALASQLL-DHTFTKVY 870
>15910
Length = 1361
Score = 108 bits (269), Expect = 8e-24, Method: Compositional matrix adjust.
Identities = 64/163 (39%), Positives = 90/163 (55%), Gaps = 7/163 (4%)
Frame = +2
Query: 145 RKALTEPEARYYLRQIVLGCQYLHRNRVIHRDLKLGNLF---LNEDLEVKIGDFGLATKV 201
R TE +A + I+ G QY+H N V+HRDLK NL + +D ++K+ DFGL+ +
Sbjct: 446 RGQYTEKDAARAISDILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLADFGLSRII 625
Query: 202 EYDGERKKTLCGTPNYIAPEVLSKKGHSFEVDVWSIGCIMYTLLVGKPPFETSCLKETYL 261
E + + T+CGTP Y APEVL ++ VD+WS+G I Y LL G PF E Y
Sbjct: 626 EPEVQMS-TVCGTPGYCAPEVLKGDKYTPSVDMWSVGVIAYILLCGYEPFFAENEFEMYR 802
Query: 262 RIKKNEYSIPK----HINPVAASLIQKMLQTDPTARPTINELL 300
+I K EY + I+ A +++K+L DP R T E L
Sbjct: 803 KIIKGEYKFDEEYWSEISENAKDVVRKLLVIDPKKRLTATEAL 931
>03240
Length = 1683
Score = 105 bits (262), Expect = 5e-23, Method: Compositional matrix adjust.
Identities = 77/264 (29%), Positives = 123/264 (46%), Gaps = 47/264 (17%)
Frame = -3
Query: 59 LGKGGFAKCFEISDADTKEVFAGKIVPKSLLLKPHQREKMSMEISIHRSLAHQHVVGFHG 118
LG G F + DT ++A K + KS +LK +Q + E I ++ VV +
Sbjct: 1267 LGVGAFGEVSLCRKNDTGMLYAMKTLRKSDVLKRNQVAHVKAERDILAEADNEWVVKLYY 1088
Query: 119 FFEDNDFVFVVXXXXXXXXXXXXHKRRKALTEPEARYYLRQIVLGCQYLHRNRVIHRDLK 178
F+D+++++ V R + L EP AR+Y+ ++V + +HR IHRD+K
Sbjct: 1087 SFQDHNYLYFVMDYVPGGDLMGLLIRMEILDEPLARFYVAELVQAIESVHRMGFIHRDIK 908
Query: 179 LGNLFLNEDLEVKIGDFGLATKVEY---------DG------------------------ 205
N+ ++ + +K+ DFGL T + DG
Sbjct: 907 PDNILIDRNGHIKLTDFGLCTGFRWTHNSKYYQRDGTHARQDSMEVKCQLDEQCQCEILK 728
Query: 206 --ERKK---------TLCGTPNYIAPEVLSK-KGHSFEVDVWSIGCIMYTLLVGKPPFET 253
ER++ +L GTPNYIAPEVLS+ G++ D WS+G I++ +LVG PPF
Sbjct: 727 PLERRRKREQRCLAHSLVGTPNYIAPEVLSRLGGYTSVCDWWSVGVILFEMLVGHPPFYA 548
Query: 254 SCLKETYLRI--KKNEYSIPKHIN 275
+ ET ++ K+ IP+ N
Sbjct: 547 NTPAETQYKVINWKDMLKIPRESN 476
>12721
Length = 821
Score = 103 bits (256), Expect = 3e-22, Method: Compositional matrix adjust.
Identities = 66/217 (30%), Positives = 109/217 (50%), Gaps = 5/217 (2%)
Frame = +1
Query: 84 VPKSLLLKPHQREKMSMEISIHRSLAHQHVVGFHGFFEDNDFVFVVXXXXXXXXXXXXHK 143
V K L K +RE + E+ + R H ++V + + ND ++VV
Sbjct: 175 VKKMDLRKQQRRELLFNEVVVMRDYHHPNIVEMYNSYLVNDELWVVMEFMEGGALTDIVT 354
Query: 144 RRKALTEPEARYYLRQIVLGCQYLHRNRVIHRDLKLGNLFLNEDLEVKIGDFGLATKVEY 203
+ + E + R + +LH N VIHRD+K ++ L+ D +VK+ DFG +V
Sbjct: 355 NNR-MDEVQIATVCRACLKALAFLHANGVIHRDIKSDSILLSHDGKVKLXDFGFCAQVTQ 531
Query: 204 DGERKKTLCGTPNYIAPEVLSKKGHSFEVDVWSIGCIMYTLLVGKPPFETSCLKETYLRI 263
D +++K+L GTP ++APEV+S+ + EVD+WS+G ++ ++ +PPF + RI
Sbjct: 532 DLQKRKSLVGTPYWMAPEVISRLPYGPEVDIWSLGIMVMEMIDAEPPFFNEPPLQAMRRI 711
Query: 264 KKNEYSIPK-----HINPVAASLIQKMLQTDPTARPT 295
+ + PK I+P I +ML DP R T
Sbjct: 712 R--DMPPPKLRNTHKISPRLQGFIDRMLVRDPHQRAT 816
>13212
Length = 1067
Score = 99.4 bits (246), Expect = 3e-21, Method: Compositional matrix adjust.
Identities = 56/169 (33%), Positives = 85/169 (50%), Gaps = 8/169 (4%)
Frame = -1
Query: 145 RKALTEPEARYYLRQIVLGCQYLHRNRVIHRDLKLGNLFLNEDLEVKIGDFGLATKVEYD 204
K +TE + Y ++ + +LHR+ VIHRD+K GN+ L D EVK+ DFG++ K
Sbjct: 998 EKPMTEAQICYVCHEMCMALDFLHRHHVIHRDIKAGNVLLTIDGEVKLADFGVSAKNTQT 819
Query: 205 GERKKTLCGTPNYIAPEV-----LSKKGHSFEVDVWSIGCIMYTLLVGKPPFETSCLKET 259
+++ T GTP ++APEV L + F+ D+WS+G + +PP +
Sbjct: 818 QQKRDTFIGTPYWMAPEVVLCETLKDTPYDFKADIWSLGVTLIEFAQIEPPNKEMHPMRV 639
Query: 260 YLRIKKNEYSI---PKHINPVAASLIQKMLQTDPTARPTINELLNDEFF 305
++I K++ PK + I K L DP RPT ELL F
Sbjct: 638 LIKIHKSDPPTLEKPKKWTKLFKDFIAKCLVKDPNLRPTAAELLEHPFM 492
>13592
Length = 980
Score = 95.9 bits (237), Expect = 4e-20, Method: Compositional matrix adjust.
Identities = 69/263 (26%), Positives = 126/263 (47%), Gaps = 13/263 (4%)
Frame = +2
Query: 59 LGKGGFAKCFEISDADTKEVFAGKIVPKSLLLKPHQR---EKMSMEISIHRSLAHQHVVG 115
+G+G F K + + +T E+ A K + ++P + + ++ E+ I + H+++V
Sbjct: 8 IGQGRFGKVYTAVNNNTGELMA----MKEIAIQPGETRALKNVAEELKILEGIKHKNLVR 175
Query: 116 FHGFFEDNDFVFVVXXXXXXXXXXXXHKRRKALTEPEARYYLRQIVLGCQYLHRNRVIHR 175
++G + + + + L E +R + Q++ G LH++ ++HR
Sbjct: 176 YYGIEVHREELLIFMELCSEGTLESLVELTGGLPEALSRRFTAQLLSGVAELHKHGIVHR 355
Query: 176 DLKLGNLFL-NEDLEVKIGDFGLATKVEYD----GERKKTLCGTPNYIAPEVLSK---KG 227
D+K N+FL + +K+GDFG A K++ GE + + GT Y+APEV +K G
Sbjct: 356 DIKTANIFLVDGSNSLKLGDFGSAVKIQAHTTVPGELQGYV-GTQAYMAPEVFTKTNSDG 532
Query: 228 HSFEVDVWSIGCIMYTLLVGKPPF-ETSCLKETYLRIKKNEY-SIPKHINPVAASLIQKM 285
H D+WS+GC++ + GK P+ + + ++ E P+ ++ I
Sbjct: 533 HGRLADIWSVGCVVVEMASGKRPWAQFDSNFQIMFKVGMGEKPQAPESLSQEGHDFIDHC 712
Query: 286 LQTDPTARPTINELLNDEFFTSG 308
LQ DP R + ELL F SG
Sbjct: 713 LQHDPKQRLSAIELLEQNFCKSG 781
>14420
Length = 528
Score = 87.4 bits (215), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 40/116 (34%), Positives = 69/116 (59%)
Frame = +2
Query: 147 ALTEPEARYYLRQIVLGCQYLHRNRVIHRDLKLGNLFLNEDLEVKIGDFGLATKVEYDGE 206
+ E + R+ + ++LH N+VIHRD+K N+ L D VK+ DFG ++ +
Sbjct: 185 CMDEGQIAAVCRECLQALEFLHENQVIHRDIKSDNILLGMDGSVKLTDFGFCAQLSPEQS 364
Query: 207 RKKTLCGTPNYIAPEVLSKKGHSFEVDVWSIGCIMYTLLVGKPPFETSCLKETYLR 262
++ T+ GTP ++APEV+++K + VD+WS+G + ++ G+PP+ L E LR
Sbjct: 365 KRSTMVGTPYWMAPEVVTRKQYGPTVDIWSLGVMCIEMIEGEPPY----LNENPLR 520
>26560
Length = 398
Score = 86.3 bits (212), Expect = 4e-17, Method: Compositional matrix adjust.
Identities = 44/106 (41%), Positives = 66/106 (62%), Gaps = 2/106 (1%)
Frame = -1
Query: 148 LTEPEARYYLRQIVLGCQYLHRNRVIHRDLKLGNLFLNEDLEVKIGDFGLATKVEYDGER 207
TE E R+Y +++LG +++H V++RDLK N+ L+E+ V+I D GLA ++ +R
Sbjct: 365 FTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGLA--CDFSKKR 192
Query: 208 KKTLCGTPNYIAPEVLSKKGHSFE--VDVWSIGCIMYTLLVGKPPF 251
GT Y+APEVL KG S++ D +S GC++Y LL G PF
Sbjct: 191 PHASVGTHGYMAPEVL-MKGQSYDSSADWFSFGCMLYKLLKGHSPF 57
>19094
Length = 898
Score = 85.1 bits (209), Expect = 8e-17, Method: Compositional matrix adjust.
Identities = 43/113 (38%), Positives = 62/113 (54%)
Frame = +1
Query: 144 RRKALTEPEARYYLRQIVLGCQYLHRNRVIHRDLKLGNLFLNEDLEVKIGDFGLATKVEY 203
R K L E E L + G YLH R IHRD+K GN+ LN + K+ DFG+A ++
Sbjct: 37 RNKTLVEREIATILYYTLKGL*YLHSRRKIHRDIKAGNILLNNEGHAKLADFGVAGQLTD 216
Query: 204 DGERKKTLCGTPNYIAPEVLSKKGHSFEVDVWSIGCIMYTLLVGKPPFETSCL 256
++ T+ GTP ++APEV+ + G+ D+WS+G + G ETS L
Sbjct: 217 TMAKRNTVIGTPYWMAPEVIQEIGYDCVADIWSLGITALEMAEGNLHMETSIL 375
>09606
Length = 1300
Score = 84.3 bits (207), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 60/248 (24%), Positives = 107/248 (43%), Gaps = 33/248 (13%)
Frame = -3
Query: 94 QREKMSMEISIHRSLAHQHVVGFHGFFEDNDFVFVVXXXXXXXXXXXXHKRRKALTEPEA 153
+R +++ + + ++H +VV FH ++E ++ +++V + L E
Sbjct: 1004 KRPEVTNTVRMTHDISHPNVVQFHEWYETSNHLWLVVELCTGGSLADILAQDHHLPETSI 825
Query: 154 RYYLRQIVLGCQYLHRNRVIHRDLKLGNLFLNEDLEVKIGDFGLATKVEYDGERKKTL-- 211
R + +V G Y+H ++ DL+ + L+ +K DFGL +KVE GE + L
Sbjct: 824 RDFGIHLVTGLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGL-SKVE--GENLEELFF 654
Query: 212 -----------------------CGTPNYIAPEVLSKKGHSFEVDVWSIGCIMYTLLVGK 248
G+P Y+APEV S D+W++GC+ Y + G
Sbjct: 653 KFAEAGDQWNIQSAEEMMKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSGH 474
Query: 249 PPFETSCLKETYLRIKKNEYSIPK--------HINPVAASLIQKMLQTDPTARPTINELL 300
PPF T ++ E+ +PK +P +L++ +LQ D T R + L+
Sbjct: 473 PPFLGETYDITKDKVLNKEFPLPKVKGSRLSAKPSPEFLNLLESLLQKDSTRRLSWASLV 294
Query: 301 NDEFFTSG 308
F+ G
Sbjct: 293 KHAFWQGG 270
>21433
Length = 590
Score = 83.6 bits (205), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 48/132 (36%), Positives = 70/132 (53%)
Frame = +2
Query: 156 YLRQIVLGCQYLHRNRVIHRDLKLGNLFLNEDLEVKIGDFGLATKVEYDGERKKTLCGTP 215
Y+ Q+ +Y H +VIHRD+K NL L ++KI DFG + V R+ T+CGT
Sbjct: 182 YIYQLSSALEYCHYRKVIHRDIKPENLLLGLKGDLKIADFGWS--VHAPSSRRTTMCGTL 355
Query: 216 NYIAPEVLSKKGHSFEVDVWSIGCIMYTLLVGKPPFETSCLKETYLRIKKNEYSIPKHIN 275
+Y+ PE++ K H VD+WS+G + Y LVG PP S + + P +
Sbjct: 356 DYLPPEMVEGKTHDENVDLWSLGVLCYEFLVGTPPLRPSPTRPPTPASPRWTSGSPSIVT 535
Query: 276 PVAASLIQKMLQ 287
P A LI K+L+
Sbjct: 536 PGARDLISKLLR 571
>25019
Length = 730
Score = 57.4 bits (137), Expect(2) = 4e-16, Method: Compositional matrix adjust.
Identities = 25/58 (43%), Positives = 35/58 (60%)
Frame = +3
Query: 181 NLFLNEDLEVKIGDFGLATKVEYDGERKKTLCGTPNYIAPEVLSKKGHSFEVDVWSIG 238
N+ L++D VK+ DFGL + T CGT Y+APE+L++ GH VD WS+G
Sbjct: 264 NVLLDKDGHVKLTDFGLCKEAITGTRVTHTFCGTIEYMAPEILTRTGHGKAVDWWSLG 437
Score = 45.4 bits (106), Expect(2) = 4e-16, Method: Compositional matrix adjust.
Identities = 22/60 (36%), Positives = 35/60 (58%)
Frame = +1
Query: 234 VWSIGCIMYTLLVGKPPFETSCLKETYLRIKKNEYSIPKHINPVAASLIQKMLQTDPTAR 293
VW G +MY +L G PPF K+T +I K + ++P ++ A LI+K+L+ +P R
Sbjct: 430 VW--GALMYDMLTGSPPFTAENRKKTIDKILKGKLNLPPYLTNEARGLIKKLLRKNPAER 603
>01392
Length = 1806
Score = 80.5 bits (197), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 58/192 (30%), Positives = 88/192 (45%), Gaps = 32/192 (16%)
Frame = -1
Query: 148 LTEPEARYYLRQIVLGCQYLHRNRVIHRDLKLGNLF---LNEDLEVKIGDFGLATKVEYD 204
L E EA +R I +LH + HRDLK N+ L++ + VKI DF LA+ + D
Sbjct: 1800 LCEREASLVVRHIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGISCD 1621
Query: 205 GERKKTL-----CGTPNYIAPEVLSKK-GHSFE----VDVWSIGCIMYTLLVGKPPFETS 254
G+ KT G+ Y+APEV+ G SF D+WS+G I+Y +L G PPF
Sbjct: 1620 GDGTKTPELLTPVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILYIMLCGYPPFYGQ 1441
Query: 255 CLKET---------------YLRIKKNEYSIPKH----INPVAASLIQKMLQTDPTARPT 295
C ++ + I+ Y P I+ A LI+ +L +P R +
Sbjct: 1440 CGEDCGWNRGEACHDCQDMLFNSIQDGHYKFPSQEWTSISSSAKDLIRHLLVREPRKRYS 1261
Query: 296 INELLNDEFFTS 307
++L + +
Sbjct: 1260 AADVLKHPWICT 1225
>00486
Length = 797
Score = 80.1 bits (196), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 35/84 (41%), Positives = 53/84 (63%)
Frame = -2
Query: 210 TLCGTPNYIAPEVLSKKGHSFEVDVWSIGCIMYTLLVGKPPFETSCLKETYLRIKKNEYS 269
T CGT Y+APE+L++ GH VD WS+G +MY +L G PPF K+T +I K + +
Sbjct: 781 TFCGTIEYMAPEILTRTGHGKAVDWWSLGALMYDMLTGSPPFTAENRKKTIDKILKGKLN 602
Query: 270 IPKHINPVAASLIQKMLQTDPTAR 293
+P ++ A LI+K+L+ +P R
Sbjct: 601 LPPYLTNEARGLIKKLLRKNPAER 530
>21079
Length = 878
Score = 79.7 bits (195), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 44/106 (41%), Positives = 62/106 (58%), Gaps = 2/106 (1%)
Frame = +1
Query: 147 ALTEPEARYYLRQIVLGCQYLHRNRVIHRDLKLGNLFLNEDL--EVKIGDFGLATKVEYD 204
LTE + +++RQI G Y+H ++H DLK N+ D ++KI DFGLA +
Sbjct: 115 VLTERDCVHFVRQICSGVGYMHTQSILHLDLKPENVLCVSDNSNQIKIIDFGLA-RFYKP 291
Query: 205 GERKKTLCGTPNYIAPEVLSKKGHSFEVDVWSIGCIMYTLLVGKPP 250
G+ + L GTP +IAPEV++ +F D+WSIG I Y LL G P
Sbjct: 292 GDSLQVLFGTPEFIAPEVVNYDEINFTTDMWSIGVICYILLSGLSP 429
>31885
Length = 529
Score = 79.7 bits (195), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 46/149 (30%), Positives = 76/149 (51%), Gaps = 5/149 (3%)
Frame = -2
Query: 108 LAHQHVVGFHGFFEDNDFVFVVXXXXXXXXXXXXHKRRKALTEPEARYYLRQIVLGCQYL 167
L H +V F+D + +F+V ++ + E ++YL Q+ L YL
Sbjct: 501 LDHPFLVNLWYAFQDEEDLFMVVDLFLGGDLRYHMQQEVSFREDCVKFYLCQLALVLDYL 322
Query: 168 HRNRVIHRDLKLGNLFLNEDLEVKIGDFGLATKVEYDGERKKTLCGTPNYIAPEVLS--- 224
+++HRD+K N+ L+E + DF +AT++E D E + GT Y+APEV
Sbjct: 321 RSQKIVHRDIKPDNILLDEQGHCHVTDFNIATQLE-DDELATSTSGTRPYMAPEVYGVAI 145
Query: 225 --KKGHSFEVDVWSIGCIMYTLLVGKPPF 251
++G+ F VD WS+G ++ LL + PF
Sbjct: 144 NERRGYGFPVDWWSLGVSLFELLKKRRPF 58
>01060
Length = 1800
Score = 75.9 bits (185), Expect = 5e-14, Method: Compositional matrix adjust.
Identities = 60/237 (25%), Positives = 99/237 (41%), Gaps = 32/237 (13%)
Frame = +1
Query: 101 EISIHRSLAHQHVVGFHGFFEDNDFVFVVXXXXXXXXXXXXHKRRKA--LTEPEARYYLR 158
EI++ R L H ++V +++ +F+V K + L + Y+
Sbjct: 220 EIAMLRELRHTNIVCLEDVIMEDERLFLVFEFLSMDLKMYIDKFPEGVVLDRRLVKSYVF 399
Query: 159 QIVLGCQYLHRNRVIHRDLKLGNLFLNEDLEVKIGDFGLATKVEYDGERKKTLCGTPNYI 218
QIV G + H+ R++HRDLK NL +N +KI DFG+A T Y
Sbjct: 400 QIVTGIXFCHQRRIVHRDLKPQNLLINHTGAIKIADFGMARTFALPVRAYTHEVVTLWYR 579
Query: 219 APEVL-SKKGHSFEVDVWSIGCIMYTLLVGKPPFETSCLKETYLRIKK-----NEYSIPK 272
APE+L +S VDVWSIG I +L+ P F+ + +I + E + P+
Sbjct: 580 APEILMGASKYSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPE 759
Query: 273 H------------------------INPVAASLIQKMLQTDPTARPTINELLNDEFF 305
++ + LI++ L+ DP R + ++L +F
Sbjct: 760 FHKLPAFNGMFPLWKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYF 930
>19761
Length = 473
Score = 74.3 bits (181), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 39/136 (28%), Positives = 71/136 (52%), Gaps = 2/136 (1%)
Frame = -3
Query: 156 YLRQIVLGCQYLHRNR--VIHRDLKLGNLFLNEDLEVKIGDFGLATKVEYDGERKKTLCG 213
+L Q Y+H + ++HRDLK N+++ E +V++GD GLA K+ + + G
Sbjct: 408 WLMQTASALNYMHTHTPVILHRDLKPQNIYVTEKGDVRLGDLGLARKLTGPADFATSQVG 229
Query: 214 TPNYIAPEVLSKKGHSFEVDVWSIGCIMYTLLVGKPPFETSCLKETYLRIKKNEYSIPKH 273
T Y++PE+LS++ ++ + D+WS+GC+ Y + K E + + + +P H
Sbjct: 228 TIMYLSPEILSQQPYNSKSDIWSLGCVFYDITGKKGSDEMGVMFLLVQVMGGRKLPLPDH 49
Query: 274 INPVAASLIQKMLQTD 289
+ I +ML D
Sbjct: 48 YSQEFRDTISRMLTKD 1
>29581
Length = 1278
Score = 72.8 bits (177), Expect = 4e-13, Method: Compositional matrix adjust.
Identities = 51/151 (33%), Positives = 75/151 (49%), Gaps = 8/151 (5%)
Frame = -2
Query: 107 SLAHQHVVGFHGFF--EDNDFVFVVXXXXXXXXXXXXHKRRKALTEPEARYYLRQIVLGC 164
+L HQ++V + D +F+V +E + + + Q++ G
Sbjct: 1187 NLRHQNIVQLQEVVVGKSLDSLFLVMEYCEQDLASLLDNMPAPFSESQVKCIVLQLLKGL 1008
Query: 165 QYLHRNRVIHRDLKLGNLFLNEDLEVKIGDFGLATKVEYDGERKKTLCGTPN-----YIA 219
+YLH +IHRDLK+ NL + + VKI DFGLA G+ +K + TP Y A
Sbjct: 1007 RYLHEAFIIHRDLKVSNLLMTDKGCVKIADFGLARNY---GKPQKPM--TPKVVTLWYRA 843
Query: 220 PEVL-SKKGHSFEVDVWSIGCIMYTLLVGKP 249
PE+L K HS +D+WS GCI+ LL KP
Sbjct: 842 PELLFGSKTHSTAIDMWSAGCILGELLGHKP 750
>01707
Length = 757
Score = 72.4 bits (176), Expect = 5e-13, Method: Compositional matrix adjust.
Identities = 60/222 (27%), Positives = 102/222 (45%), Gaps = 6/222 (2%)
Frame = +1
Query: 59 LGKGGFAKCFEISDADTKEVFAGKIVPKSL---LLKPHQREKMSM-EISIHRSLAHQHVV 114
+G+G + F+ + +T ++ A K +S L+K K++M EI + + L H ++V
Sbjct: 88 IGEGSYGVVFKCRNKETSQLVAIKKFVESEDDPLIK-----KIAMREIRMLKQLKHPNLV 252
Query: 115 GFHGFFEDNDFVFVVXXXXXXXXXXXXHKRRKALTEPEARYYLRQIVLGCQYLHRNRVIH 174
F + +V + + L EP + + Q +L + H+ IH
Sbjct: 253 RLIEVFRRKKRLHLVFDYVDHTLLNELDRYPRGLPEPMVKRIIYQTLLAVNFCHQYNTIH 432
Query: 175 RDLKLGNLFLNEDLEVKIGDFGLATKVEYDGERKKTLCGTPNYIAPEVL-SKKGHSFEVD 233
RD+K N+ + +VK+ DFG A + G+ T Y APE+L + VD
Sbjct: 433 RDVKPENILITRQGQVKLCDFGFARILTGPGDEYTDYVATRWYRAPELLVGDTQYGPPVD 612
Query: 234 VWSIGCIMYTLLVGKPPFET-SCLKETYLRIKKNEYSIPKHI 274
VW+IGC+ LL G+ + S + + +L K IP+HI
Sbjct: 613 VWAIGCVFAELLTGQALWPGRSDVDQLHLIRKTLGDLIPRHI 738
>38560
Length = 479
Score = 71.2 bits (173), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 35/101 (34%), Positives = 57/101 (56%), Gaps = 1/101 (0%)
Frame = -3
Query: 210 TLCGTPNYIAPEVLSKKGH-SFEVDVWSIGCIMYTLLVGKPPFETSCLKETYLRIKKNEY 268
T CG+P Y APE++S + E D+WS+G ++Y LL G PF+ + +K +
Sbjct: 408 TCCGSPAYAAPELISGLEYLGSEADIWSMGVLLYALLCGYLPFDDEKXSHL*QKNQKRKD 229
Query: 269 SIPKHINPVAASLIQKMLQTDPTARPTINELLNDEFFTSGY 309
+P+ ++ L++ MLQTDP+ R TI LL+ + G+
Sbjct: 228 EVPEWLSEDTTKLLEGMLQTDPSHRITIRRLLDHHWLNQGF 106
>14126
Length = 1265
Score = 70.9 bits (172), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 37/97 (38%), Positives = 55/97 (56%)
Frame = +3
Query: 159 QIVLGCQYLHRNRVIHRDLKLGNLFLNEDLEVKIGDFGLATKVEYDGERKKTLCGTPNYI 218
Q++ G +LH NR++HRDLK NL +++D +K+ DFGLA + T+ T Y
Sbjct: 540 QLLNGVDFLHSNRIVHRDLKPQNLLISKDGRLKLADFGLARIYSFHMA-LTTVVVTLWYR 716
Query: 219 APEVLSKKGHSFEVDVWSIGCIMYTLLVGKPPFETSC 255
+PEVL + + VD+WS GCI L + F+ S
Sbjct: 717 SPEVLMQAEYGTSVDIWSCGCIFAELFTRRALFKGSS 827
>12786
Length = 460
Score = 70.1 bits (170), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 40/132 (30%), Positives = 65/132 (49%), Gaps = 22/132 (16%)
Frame = -3
Query: 143 KRRKALTEPEARYYLRQIVLGCQYLHRNRVIHRDLKLGNLFLNEDLEVKIGDFGLATKVE 202
K+ + L ++Y R+++ + LH VIH DLK N L +K+ DFG+A ++
Sbjct: 434 KQEQGLDRMMIKFYWREMLRAVKALHNEGVIHSDLKPANFMLVAG-NLKLIDFGIANTLQ 258
Query: 203 YDGER--KKTLCGTPNYIAPEV------------LSKKGH--------SFEVDVWSIGCI 240
D K + GTP+Y++PE + + GH DVWS+GCI
Sbjct: 257 QDKTSVLKDSRVGTPSYMSPEAIMAACDDSADDSMEEDGHRTKPKYKVGVRSDVWSLGCI 78
Query: 241 MYTLLVGKPPFE 252
+Y ++ G+ PF+
Sbjct: 77 LYNMVYGRTPFQ 42
>00392
Length = 668
Score = 70.1 bits (170), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 55/203 (27%), Positives = 100/203 (49%), Gaps = 9/203 (4%)
Frame = +3
Query: 94 QREKMSMEISIHRSLAHQHVVGFHGFFEDND-----FVFVVXXXXXXXXXXXXHKRRKAL 148
+R++ E + + L H ++V F ++E+++ + +V KR K
Sbjct: 60 ERQRFKEEAEMLKELQHPNIVRFFDYWEEHNHRNRKVIILVTELMTSGTLKTYLKRFKKP 239
Query: 149 TEPEARYYLRQIVLGCQYLHRNR--VIHRDLKLGNLFLNEDL-EVKIGDFGLATKVEYDG 205
+ + RQ++ G +LH VIHRDLK N+F+ VKIGD GLAT +
Sbjct: 240 NVKILKNWCRQVLKGLYFLHTRTPPVIHRDLKCDNIFITGPTGSVKIGDLGLATL--KNQ 413
Query: 206 ERKKTLCGTPNYIAPEVLSKKGHSFEVDVWSIGCIMYTLLVGKPPF-ETSCLKETYLRIK 264
K++ GTP ++APE + ++ + VDV++ G M + + P+ E S + Y R+
Sbjct: 414 SFAKSVIGTPEFMAPE-MYEEHYDEAVDVYAFGMCMLEMASSEYPYSECSNAAQIYKRVT 590
Query: 265 KNEYSIPKHINPVAASLIQKMLQ 287
+P+ ++ VA + I+ ++
Sbjct: 591 SG--VLPEALDKVAITEIRDIIH 653
>26711
Length = 405
Score = 70.1 bits (170), Expect = 3e-12, Method: Composition-based stats.
Identities = 40/115 (34%), Positives = 63/115 (54%), Gaps = 2/115 (1%)
Frame = -2
Query: 157 LRQIVLGCQYLHRNRVIHRDLKLGNLFLNEDL--EVKIGDFGLATKVEYDGERKKTLCGT 214
++Q++ Q++H V+H DLK NL L+ D V++ DFGLA K+ Y + GT
Sbjct: 398 VKQVLDILQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARKL-YPPQETFLNHGT 222
Query: 215 PNYIAPEVLSKKGHSFEVDVWSIGCIMYTLLVGKPPFETSCLKETYLRIKKNEYS 269
P + +PE L K S DVW +G + Y LL G+ PF+ E+ + + ++S
Sbjct: 221 PGFTSPEALDVKPISTASDVWGVGVLAYILLSGQSPFQADSATESLKKTQTCDWS 57
>01756
Length = 1858
Score = 69.3 bits (168), Expect = 4e-12, Method: Compositional matrix adjust.
Identities = 53/207 (25%), Positives = 88/207 (42%), Gaps = 16/207 (7%)
Frame = -3
Query: 59 LGKGGFAKCFEISDADTKEVFAGKIVPKSLLLKPHQREKMSM----EISIHRSLAHQHVV 114
+G+G F + F+ TK+V A K V L +++E + EI I + L H++VV
Sbjct: 1718 IGQGTFGEVFKARCKKTKQVVAMKKV-----LMDNEKEGFPITALREIKILQLLNHENVV 1554
Query: 115 GFHGFFEDN--------DFVFVVXXXXXXXXXXXXHKRRKALTEPEARYYLRQIVLGCQY 166
++V PE + ++Q++ G Y
Sbjct: 1553 DLIEICSTKATSANRYKSMFYLVFEFCEHDLAGLLSNMSVVFNLPEIKEVMKQLMNGLYY 1374
Query: 167 LHRNRVIHRDLKLGNLFLNEDLEVKIGDFGLATKVEYD---GERKKTLCGTPNYIAPE-V 222
+HRN+++HRD+K N+ + + +K+ DFGLA + R T Y PE +
Sbjct: 1373 IHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRPPELL 1194
Query: 223 LSKKGHSFEVDVWSIGCIMYTLLVGKP 249
L + +S +D W GCIM + P
Sbjct: 1193 LGDRNYSTAIDQWGAGCIMAEMWTRNP 1113
>18663
Length = 600
Score = 68.9 bits (167), Expect = 5e-12, Method: Compositional matrix adjust.
Identities = 32/93 (34%), Positives = 52/93 (55%), Gaps = 9/93 (9%)
Frame = +2
Query: 210 TLCGTPNYIAPEVLSKKGHSFEVDVWSIGCIMYTLLVGKPPFETSCLKET---------Y 260
T CGTPNYIAPE+L + + F VD W++G ++Y +L G+ PF+ + E +
Sbjct: 5 TFCGTPNYIAPEILRGEDYGFSVDWWALGVLLYEMLAGRSPFDIAGASENPDQNTEDYLF 184
Query: 261 LRIKKNEYSIPKHINPVAASLIQKMLQTDPTAR 293
I + IP+ ++ AAS+++ L +P R
Sbjct: 185 QVILEKTIRIPRSLSVKAASVLKGFLNKNPADR 283
>04852
Length = 1462
Score = 67.4 bits (163), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 47/165 (28%), Positives = 85/165 (51%), Gaps = 7/165 (4%)
Frame = +1
Query: 144 RRKALTEPEARYYLRQIVLGCQYLHRNRVIHRDLKLGNLFLNEDLEVKIGDFGLATKVEY 203
RRK L Y QI G ++L + IHRDL N+ + E+ +KI DFGL+ +Y
Sbjct: 319 RRKNLLS-----YAFQIARGMEFLASRKCIHRDLAARNVLVTEEHVLKIADFGLSRTGDY 483
Query: 204 DGERKKTLCGTP-NYIAPEVLSKKGHSFEVDVWSIGCIMYTLL-VGKPPFETSCLKETYL 261
+K++ P ++APE L ++ + DVWS G +++ + +G P+ + +E Y
Sbjct: 484 --YKKRSGGRLPVKWMAPEALFDMRYTTKSDVWSFGVVLWEIFSLGGMPYASIPNEELYS 657
Query: 262 RIKKNEYSIPKHINPVAAS-----LIQKMLQTDPTARPTINELLN 301
++ + Y +P+ P AS ++++ P+ RP ++L+
Sbjct: 658 KLLDDAYRMPR---PELASGNLYAIMERCWLNRPSDRPEFSQLVG 783
>04138
Length = 800
Score = 67.0 bits (162), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 48/187 (25%), Positives = 79/187 (42%), Gaps = 38/187 (20%)
Frame = +1
Query: 166 YLHRNRVIHRDLKLGNLFLNEDLEVKIGDFGLATKVEYD---GERKKTLCGTPNYIAPE- 221
Y+HRN+++HRD+K N+ + + +K+ DFGLA + R T Y PE
Sbjct: 58 YIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRPPEL 237
Query: 222 VLSKKGHSFEVDVWSIGCIMYTLLVGKPPFETSCLKE----------------------- 258
+L + +S +D W GCIM + P + + +
Sbjct: 238 LLGDRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQNQLTLITQLCGSITPEVWPGVTQL 417
Query: 259 -TYLRIKKNEYSIPKHI----------NPVAASLIQKMLQTDPTARPTINELLNDEFFTS 307
Y +IK + K+I +P L +++L+ DP+ R + +E LN +FF
Sbjct: 418 SMYHQIKGALAAGRKNIIRDRFARILKDPYGLDLFERLLKMDPSQRISADEALNHDFFWV 597
Query: 308 GYIPARL 314
G P L
Sbjct: 598 GVEPKSL 618
>01718
Length = 959
Score = 66.6 bits (161), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 52/190 (27%), Positives = 86/190 (45%), Gaps = 7/190 (3%)
Frame = +3
Query: 59 LGKGGFAKCFEISDADTKEVFAGKIVPKSLLLKPHQREKMSMEISIHRSLAHQHVVGFHG 118
+G G F++ F+++ T +V A K+ + R M E+ + L H +++ F G
Sbjct: 171 IGAGFFSEVFKVTHRITGQVMALKMNTMT-----SNRHNMLREVQLLNRLQHANILRFMG 335
Query: 119 F-FEDNDFVFVVXXXXXXXXXXXXHKRRKALTEPEARYYLRQIVLGCQYLHRNRVIHRDL 177
+ + K+ + L + + G YLH R IHRDL
Sbjct: 336 VCVHEGQLHALTEYIPSGNLEQLLEKKDEELPWTQRIQLTLGLARGLDYLHSTRFIHRDL 515
Query: 178 KLGNLFL----NEDLEVKIGDFGLATKVE--YDGERKKTLCGTPNYIAPEVLSKKGHSFE 231
N+ + N I DFGLATK+ D E+ T+ G+P ++APEVL+ ++
Sbjct: 516 TSKNILIRREDNHGYHAVIADFGLATKIPDPLDKEKLPTV-GSPYWMAPEVLNGHFYNER 692
Query: 232 VDVWSIGCIM 241
D++S+G IM
Sbjct: 693 ADLFSVGIIM 722
>20152
Length = 445
Score = 66.2 bits (160), Expect = 4e-11, Method: Composition-based stats.
Identities = 36/92 (39%), Positives = 52/92 (56%), Gaps = 3/92 (3%)
Frame = +1
Query: 220 PEVLSKKGHSFE---VDVWSIGCIMYTLLVGKPPFETSCLKETYLRIKKNEYSIPKHINP 276
PE+L G S++ VDVWS+G I+Y L+VG+ PF+ + ET I Y IP HI+
Sbjct: 1 PEILL--GDSYDAPAVDVWSLGVILYMLVVGEAPFQEANDSETLTMIMDCRYQIPPHISH 174
Query: 277 VAASLIQKMLQTDPTARPTINELLNDEFFTSG 308
LI+KMLQ +P R ++ +L + G
Sbjct: 175 KCQDLIEKMLQREPVDRASLPHILAHPWLNDG 270
>13066
Length = 551
Score = 64.7 bits (156), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 39/142 (27%), Positives = 65/142 (45%), Gaps = 4/142 (2%)
Frame = +3
Query: 101 EISIHRSLAHQHVVGFHGFFEDNDFVFVVXXXXXXXXXXXXHKRRKALTEPEARYYLRQI 160
E+ + L H +++ H + F+ + + E +A+ + Q+
Sbjct: 126 ELDLLTKLDHPYIIQIHSILQRXPKNFIFMRFAERGDLLTYIQEVGFVKEKQAKIWFYQM 305
Query: 161 VLGCQYLHRNRVIHRDLKLGNLFLNEDLEVKIGDFGLATK-VEYDGER--KKTLCGTPNY 217
YLH V HRDLK N+ L+ VK+ DFG A + GE+ +T CG+ Y
Sbjct: 306 TTALNYLHSYDVAHRDLKCENILLSSHFNVKLADFGFACACITESGEKYMSRTYCGSAAY 485
Query: 218 IAPEVLSKKGHSFEV-DVWSIG 238
APE++ ++ +V D WS+G
Sbjct: 486 AAPEIVYGAPYAPKVADAWSLG 551
>27405
Length = 532
Score = 64.7 bits (156), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 31/82 (37%), Positives = 50/82 (60%)
Frame = -3
Query: 144 RRKALTEPEARYYLRQIVLGCQYLHRNRVIHRDLKLGNLFLNEDLEVKIGDFGLATKVEY 203
+ TE E R+Y +++LG +++H V++RDLK N+ L+E+ V+I D GLA ++
Sbjct: 275 QHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGLA--CDF 102
Query: 204 DGERKKTLCGTPNYIAPEVLSK 225
++ GT Y+APEVL K
Sbjct: 101 SKKKPHASVGTHGYMAPEVLMK 36
>07940
Length = 1336
Score = 63.9 bits (154), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 37/118 (31%), Positives = 65/118 (55%), Gaps = 3/118 (2%)
Frame = -3
Query: 146 KALTEPEARYYLRQIVLGCQYLHRNRVIHRDLKLGNLFLNEDLEVKIGDFGLATKV-EYD 204
K LT + Y Q+ G +YL + IHRDL N+ + E+ +KI DFGL + ++D
Sbjct: 362 KMLTPKDLISYAYQVARGMEYLASKQCIHRDLAARNVLVAEEYVLKIADFGLTRNLQQFD 183
Query: 205 GERKKTLCGTP-NYIAPEVLSKKGHSFEVDVWSIGCIMYTLL-VGKPPFETSCLKETY 260
RK T P ++APE L + ++ + DVWS G +++ + +G P+ + +++ +
Sbjct: 182 YYRKTTDGRLPVKWMAPEALFDRKYTSKSDVWSYGVLLWEIFTLGGNPYPSVPVEDLF 9
>04591
Length = 1117
Score = 62.0 bits (149), Expect = 6e-10, Method: Compositional matrix adjust.
Identities = 56/227 (24%), Positives = 98/227 (43%), Gaps = 39/227 (17%)
Frame = -2
Query: 152 EARYYLRQIVLGCQYLHRNRVIHRDLKLGNLFLNEDLEVKIGDFGLATKVEYDGERKKTL 211
+ + + Q++ G Y+H +++HRD+K N+ L D +K+ DFGL ++ +R
Sbjct: 894 DKKNLMSQLLNGLFYIHTKQILHRDIKAANILLTRDGVLKLADFGL-SRPWVKSKRLTNR 718
Query: 212 CGTPNYIAPE-VLSKKGHSFEVDVWSIGCIMYTLLVGKPPFE---------------TSC 255
T Y PE +L ++ + E+D+W +GCIM + KP + S
Sbjct: 717 VVTLWYRPPELLLGEREYGPEIDMWGVGCIMAEMWSRKPLMQGRSEQHQLSLITDLCGSL 538
Query: 256 LKETYLRIKKNEY--------SIPKHI---------NPVAASLIQKMLQTDPTARPTINE 298
E + + K E P+ + N A LI L+ DP R +
Sbjct: 537 NAEVWPGVTKLELYGKLDLPQGKPRKVKERMLDLLKNKEGAELIDIFLRLDPGQRMNCDN 358
Query: 299 LLNDEFFTSGYIPARLPITCLT-IPPRFSIA----PSSLDPSN-RKP 339
L+ +FF +P+ + L+ +PP + P + +P N R+P
Sbjct: 357 ALSHDFFWVDPLPSPSLTSILSNLPPMHELGVVRRPPARNPQNSRQP 217
>06405
Length = 1965
Score = 61.2 bits (147), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 45/148 (30%), Positives = 63/148 (42%), Gaps = 3/148 (2%)
Frame = +1
Query: 155 YYLRQIVLGCQYLHRNRVIHRDLKLGNLFLNEDLEVKIGDFGLATKVEYDGERKKTLCGT 214
Y QI G YL IHRDL N + + VK+ DFGLA ++ D
Sbjct: 565 YMATQIASGMAYLETKNFIHRDLAARNCLVADSNMVKVADFGLARLMKDDTYTAHIGAKF 744
Query: 215 P-NYIAPEVLSKKGHSFEVDVWSIGCIMYTLLV-GKPPFETSCLKETYLRIKKN-EYSIP 271
P + APE L+ S D+W+ G +++ L G P+ L E Y +++ P
Sbjct: 745 PIKWTAPEGLAFNRFSTRSDIWAFGVLLWELATYGMSPYPGVELTEVYHLLERGYRMERP 924
Query: 272 KHINPVAASLIQKMLQTDPTARPTINEL 299
L+ K Q DP RPT E+
Sbjct: 925 PGTPADVYILMLKCWQWDPKDRPTFKEI 1008
>21808
Length = 1011
Score = 59.7 bits (143), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 45/179 (25%), Positives = 75/179 (41%), Gaps = 3/179 (1%)
Frame = +1
Query: 76 KEVFAGKIVPKSLLLKPHQREKMSMEISIHRSLAHQHVVGFHGFFEDNDFVFVVXXXXXX 135
K + +G + PK L E I + L H ++ + +D +F++
Sbjct: 37 KTLKSGTMDPKDFL----------AEAQIMKKLRHPKLIQLYAVCTQDDPIFIITELMKN 186
Query: 136 XXXXX-XHKRRKALTEPEARYYLRQIVLGCQYLHRNRVIHRDLKLGNLFLNEDLEVKIGD 194
+ + L P QI G YL IHRDL N+ ++++ VKI D
Sbjct: 187 GSLLEFLQGKGRVLKLPALIDIGAQIACGMAYLESQNYIHRDLAARNILVSDNNTVKIAD 366
Query: 195 FGLATKVEYDGERKKTLCGTP-NYIAPEVLSKKGHSFEVDVWSIGCIMY-TLLVGKPPF 251
FGLA ++ D + P + APE + + + DVWS G ++ T+ G+ P+
Sbjct: 367 FGLARVIKEDEYEARVGARFPIKWTAPEAANYNRFTIKSDVWSFGILLTETVTYGRVPY 543
>02638
Length = 1490
Score = 58.5 bits (140), Expect = 8e-09, Method: Compositional matrix adjust.
Identities = 33/106 (31%), Positives = 54/106 (50%), Gaps = 5/106 (4%)
Frame = +1
Query: 206 ERKKTLCGTPNYIAPEVLSKKGHSFEVDVWSIGCIMYTLLVGKPPFETSCLKETYLRIKK 265
E + L GT ++APEVL + + DVWS+GC+M + +PP+ + + I K
Sbjct: 1 EFQGQLLGTIAFMAPEVLRGESYGRACDVWSVGCVMIEMCTCRPPWNSHDISNHLALIFK 180
Query: 266 NEYS-----IPKHINPVAASLIQKMLQTDPTARPTINELLNDEFFT 306
S IP++++P L+ + L+ D RP+ +LL FT
Sbjct: 181 IASSVDPPPIPENMSPPVRDLMLRCLEQDSDFRPSAKDLLMHPLFT 318
>14116
Length = 1017
Score = 58.2 bits (139), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 34/93 (36%), Positives = 46/93 (49%), Gaps = 3/93 (3%)
Frame = -1
Query: 156 YLRQIVLGCQYLHRNRVIHRDLKLGNLFLNEDLEVKIGDFGLATKV---EYDGERKKTLC 212
Y I G YL + +HRDL N L+ED VK+ DFGLA + EY K
Sbjct: 306 YGVDIARGMDYLAGLKFVHRDLAARNCMLDEDFHVKVADFGLARDIYEKEYYSSENKKAK 127
Query: 213 GTPNYIAPEVLSKKGHSFEVDVWSIGCIMYTLL 245
++A E L K + + DVWS G +++ LL
Sbjct: 126 LPVKWMALESLEKGNYDSKTDVWSYGVVLWELL 28
>01966
Length = 1735
Score = 57.4 bits (137), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 40/142 (28%), Positives = 62/142 (43%), Gaps = 2/142 (1%)
Frame = -1
Query: 101 EISIHRSLAHQHVVGFHGFFEDNDFVFVVXXXXXXXXXXXXHKRRKA--LTEPEARYYLR 158
EI++ R L H ++V +++ +F+V K + L + Y+
Sbjct: 1564 EIAMLRELRHTNIVCLEDVIMEDERLFLVFEFLSMDLKMYIDKFPEGVVLDRRLVKSYVF 1385
Query: 159 QIVLGCQYLHRNRVIHRDLKLGNLFLNEDLEVKIGDFGLATKVEYDGERKKTLCGTPNYI 218
QIV G + H+ R++HRDLK NL +N +KI DFG+A T Y
Sbjct: 1384 QIVTGINFCHQRRIVHRDLKPQNLLINHTGAIKIADFGMARTFALPVRAYTHEVVTLWYR 1205
Query: 219 APEVLSKKGHSFEVDVWSIGCI 240
APE+L G W+ G +
Sbjct: 1204 APEIL--MGPQSTPPXWTCGAL 1145
Score = 28.9 bits (63), Expect = 6.9, Method: Compositional matrix adjust.
Identities = 23/107 (21%), Positives = 42/107 (39%), Gaps = 29/107 (27%)
Frame = -3
Query: 228 HSFEVDVWSIGCIMYTLLVGKPPFETSCLKETYLRIKK-----NEYSIPK---------- 272
+S VDVWSIG I +L+ P F+ + +I + E + P+
Sbjct: 1175 YSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKLPAFNGM 996
Query: 273 --------------HINPVAASLIQKMLQTDPTARPTINELLNDEFF 305
++ + LI++ L+ DP R + ++L +F
Sbjct: 995 FPLWKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYF 855
>00715
Length = 1788
Score = 56.6 bits (135), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 34/116 (29%), Positives = 50/116 (43%), Gaps = 22/116 (18%)
Frame = +1
Query: 159 QIVLGCQYLHRNRVIHRDLKLGNLFLNEDLEVKIGDFGLATKVE---------------- 202
Q+ G YLH ++H DLK N L DL+++I DFG ++
Sbjct: 262 QMARGLHYLHSINIVHLDLKPANCLLTRDLKLRIADFGCCHQLTPTGLDMGEREGGMAGN 441
Query: 203 ------YDGERKKTLCGTPNYIAPEVLSKKGHSFEVDVWSIGCIMYTLLVGKPPFE 252
G K L GT Y APE+L S DV+S+G ++ + + P+E
Sbjct: 442 ELELTPVQGAWKNELAGTLAYRAPELLKGLQPSVRSDVYSLGITLWQMCTRQGPYE 609
>27546
Length = 426
Score = 56.2 bits (134), Expect = 4e-08, Method: Composition-based stats.
Identities = 28/98 (28%), Positives = 46/98 (46%)
Frame = -1
Query: 101 EISIHRSLAHQHVVGFHGFFEDNDFVFVVXXXXXXXXXXXXHKRRKALTEPEARYYLRQI 160
E+ I L H +++ H + +F+ K+ + E + + + Q+
Sbjct: 330 ELEILTRLDHPNIIQIHSILQRGPKIFIFMRYAEKGDMLSHIKKTGPIDEAQTKVWFFQM 151
Query: 161 VLGCQYLHRNRVIHRDLKLGNLFLNEDLEVKIGDFGLA 198
QYLH + + HRDLK N+ L++ L VKI DFG A
Sbjct: 150 AKALQYLHSHDIAHRDLKCENILLSKRLNVKIADFGFA 37
>07291
Length = 833
Score = 55.5 bits (132), Expect = 6e-08, Method: Compositional matrix adjust.
Identities = 51/178 (28%), Positives = 78/178 (43%), Gaps = 14/178 (7%)
Frame = +1
Query: 143 KRRKALTEPEARYYLRQIVLGCQYLHRNRVIHRDLKLGNLFLNEDLEVKIGDFGLATKV- 201
K K LT + + RQI G YL +V+HR+L N + ED +++ D+G+ +
Sbjct: 25 KPSKMLTVVQLLDFGRQIADGMAYLQEVKVVHRNLAARNCIVTEDGRLQLSDYGVTGSLF 204
Query: 202 -----EYDGERKKTLCGTPNYIAPEVLSKKGHSFEVDVWSIGCIMYTLLV-GKPPF---E 252
D + L ++APE + S + DVW+ G +++ LL G P+ E
Sbjct: 205 PQSYYTADDSPARDLV---KWMAPETIDNFHFSSKSDVWAFGVVLWELLTRGITPYPDVE 375
Query: 253 TSC----LKETYLRIKKNEYSIPKHINPVAASLIQKMLQTDPTARPTINELLNDEFFT 306
S LKE + R+KK PK ++ P RP E LND+ T
Sbjct: 376 NSSLLPYLKEGH-RMKK-----PKQSPEPVYEMMTACWNESPEQRPDFAE-LNDQLKT 528
>09007
Length = 1440
Score = 55.1 bits (131), Expect = 8e-08, Method: Compositional matrix adjust.
Identities = 60/258 (23%), Positives = 102/258 (39%), Gaps = 16/258 (6%)
Frame = -1
Query: 59 LGKGGFA---KCFEISDADTKEVFAGKIVPKSLLLKPHQREKMSMEISIHRSLAHQHVVG 115
LG+G F + +++ K A K + K + K Q + E +I + L H+++V
Sbjct: 855 LGQGHFGTVRQAIWTAESGEKVQVAVKCLSKDKIHKDGQ--EFLKETAIMQMLDHENIVR 682
Query: 116 FHGFFEDN--DFVFVVXXXXXXXXXXXXHK--RRKALTEPEARYYLRQIVLGCQYLHRNR 171
+G DN D + V + R + P + +Q+ G YL R
Sbjct: 681 VYGVVMDNGADIMLVTELAPMRSLLECVKEVSARVDFSVPRLCDFSQQVCDGMSYLESKR 502
Query: 172 VIHRDLKLGNLFLNEDLEVKIGDFGL-----ATKVEYDGERKKTLCGTPNYIAPEVLSKK 226
++HRDL N+ L +VKI D G+ A K Y ++ L + APE
Sbjct: 501 LVHRDLAARNILLFSKSKVKISDVGVSGALGAGKEYYQSQQTIHLQNAVAWCAPESFRNL 322
Query: 227 GHSFEVDVWSIGCIMYTLLV-GKPPF---ETSCLKETYLRIKKNEYSIPKHINPVAASLI 282
S DVW+ G +++ G P+ + E + P +++
Sbjct: 321 CFSSASDVWAFGVLLWEFFTHGFQPWAGLNGQQIMEAVDAPQSQRLEQPDLCPKEYYAVM 142
Query: 283 QKMLQTDPTARPTINELL 300
K + +P RPT ++L
Sbjct: 141 LKCWEQEPQRRPTFSQLF 88
>17300
Length = 480
Score = 55.1 bits (131), Expect = 9e-08, Method: Compositional matrix adjust.
Identities = 33/106 (31%), Positives = 56/106 (52%), Gaps = 5/106 (4%)
Frame = +1
Query: 173 IHRDLKLGNLFLNEDLEVKIGDFGLATKVEYD-GERKKTLCGTP---NYIAPEVLSKKGH 228
+HRDL N+ +NE L K+ DFGL+ ++E D E T G + APE ++ +
Sbjct: 40 VHRDLAARNILVNEILVCKVADFGLSREIESDTTEGAYTTKGGKIPVRWTAPEAIAYRKF 219
Query: 229 SFEVDVWSIGCIMYTLL-VGKPPFETSCLKETYLRIKKNEYSIPKH 273
+ DVWS G +M+ ++ G+ P+ ++ ++K Y +P H
Sbjct: 220 TSASDVWSFGVVMWEVMSYGERPYWNWSNQDVIKAVEKG-YRLPLH 354
>11185
Length = 473
Score = 53.9 bits (128), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 44/172 (25%), Positives = 71/172 (41%), Gaps = 25/172 (14%)
Frame = +1
Query: 159 QIVLGCQYLHRNRVIHRDLKLGNLFLNEDLEVKIGDFGLATKVEYDGERKKTL------- 211
+V G Y+H ++ DL+ + L+ +K DFGL +KVE GE + L
Sbjct: 25 HLVTGLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGL-SKVE--GENLEELFFKFAEA 195
Query: 212 ------------------CGTPNYIAPEVLSKKGHSFEVDVWSIGCIMYTLLVGKPPFET 253
G+P Y+APEV S D+W++GC+ Y + G
Sbjct: 196 GDQWNIQSAEEMMKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSG------ 357
Query: 254 SCLKETYLRIKKNEYSIPKHINPVAASLIQKMLQTDPTARPTINELLNDEFF 305
+ L K + P+ +N L++ +LQ D T R + L+ F+
Sbjct: 358 -----SRLSAKPS----PEFLN-----LLESLLQKDSTRRLSWASLVKHAFW 471
>12672
Length = 773
Score = 52.0 bits (123), Expect = 7e-07, Method: Compositional matrix adjust.
Identities = 31/91 (34%), Positives = 48/91 (52%), Gaps = 6/91 (6%)
Frame = +3
Query: 163 GCQYLHRNRVIHRDLKLGNLFLNEDLEVKIGDFGLATKVEYDGERKKT------LCGTPN 216
G QYL+ N +HRD+K N+ L+ + K+GDF AT V KT + GT
Sbjct: 27 GIQYLNDNGHVHRDIKTANILLDSEYTAKVGDF--ATVVSAPSGEGKTVQNASVVIGTAA 200
Query: 217 YIAPEVLSKKGHSFEVDVWSIGCIMYTLLVG 247
Y+APE + S ++D +S G ++ ++ G
Sbjct: 201 YLAPEAIHFD-VSTKLDSYSFGVVLLEVITG 290
>32957
Length = 645
Score = 51.6 bits (122), Expect = 9e-07, Method: Compositional matrix adjust.
Identities = 24/59 (40%), Positives = 34/59 (57%)
Frame = +3
Query: 197 LATKVEYDGERKKTLCGTPNYIAPEVLSKKGHSFEVDVWSIGCIMYTLLVGKPPFETSC 255
A VE G R +T CGT Y+APEV +K + EVD W +G +++ LL + +SC
Sbjct: 3 FALCVEKSGGRTRTFCGTREYMAPEVHERKEYGKEVDWWGLGILLHELLAAQIKKHSSC 179
>03508
Length = 1463
Score = 51.2 bits (121), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 26/107 (24%), Positives = 61/107 (57%), Gaps = 2/107 (1%)
Frame = +1
Query: 146 KALTEPEARYYLRQIVLGCQYLHRNRVIHRDLKLGNLFLN-EDLEVKIGDFGLATKVEYD 204
+ T+ + R+YL +++ + H ++HRD+K N+ ++ E+ ++++ D+GLA + +
Sbjct: 856 QTFTDYDIRFYLYELMKALDFCHSMGIMHRDVKPHNVMIDHENKKLRLIDWGLA-EFYHP 1032
Query: 205 GERKKTLCGTPNYIAPE-VLSKKGHSFEVDVWSIGCIMYTLLVGKPP 250
G + + PE +L + + + +D+WS+GC+ +++ K P
Sbjct: 1033GMEYNVRVASRYFKGPELLLDYQMYDYSLDMWSLGCMFASMIFRKEP 1173
>29590
Length = 320
Score = 50.4 bits (119), Expect = 2e-06, Method: Composition-based stats.
Identities = 23/58 (39%), Positives = 34/58 (58%)
Frame = +3
Query: 194 DFGLATKVEYDGERKKTLCGTPNYIAPEVLSKKGHSFEVDVWSIGCIMYTLLVGKPPF 251
D G A + GE + + GTP+Y+APEVL + S + D+WS+G + Y +L PF
Sbjct: 6 DLGFAC-LTNTGEDIRDIIGTPDYVAPEVLDYEPLSIQTDMWSLGVLSYVMLTACSPF 176
>20640
Length = 1492
Score = 50.1 bits (118), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 36/131 (27%), Positives = 58/131 (44%), Gaps = 4/131 (3%)
Frame = +1
Query: 173 IHRDLKLGNLFLNEDLEVKIGDFGLATKVE-YDGERKKTLCGTP-NYIAPEVLSKKGHSF 230
+HRDL N + DL VKI DFGLA V D R P ++ E + S
Sbjct: 10 VHRDLATRNCLVGHDLVVKISDFGLARSVHSVDYYRGSEHDAIPIRWMPLEAILYNKFST 189
Query: 231 EVDVWSIGCIMYTLLV-GKPPFETSCLKETYLRIKKNEY-SIPKHINPVAASLIQKMLQT 288
+ DVWS G +++ + P+ +E +K+ + + P+ P L+++
Sbjct: 190 QSDVWSFGVVLWEIFAFALQPYYGLTHEEVVRFVKEGKVLACPERTPPPMYELMKQCWHR 369
Query: 289 DPTARPTINEL 299
P RP+ + L
Sbjct: 370 RPATRPSFHTL 402
>28638
Length = 1458
Score = 49.3 bits (116), Expect = 5e-06, Method: Compositional matrix adjust.
Identities = 28/82 (34%), Positives = 45/82 (54%), Gaps = 2/82 (2%)
Frame = -1
Query: 172 VIHRDLKLGNLFLN--EDLEVKIGDFGLATKVEYDGERKKTLCGTPNYIAPEVLSKKGHS 229
+IH DLK N+ L + +KI DFG + ++ G+R + Y +PEVL +
Sbjct: 768 IIHCDLKPENILLCNPKRSAIKIVDFGSSCQL---GQRIYQYIQSRFYRSPEVLLGVPYD 598
Query: 230 FEVDVWSIGCIMYTLLVGKPPF 251
+D+WS+GCI+ + G+PP
Sbjct: 597 LAIDMWSLGCILVEMHTGEPPL 532
>19301
Length = 712
Score = 48.9 bits (115), Expect = 5e-06, Method: Compositional matrix adjust.
Identities = 32/121 (26%), Positives = 55/121 (45%)
Frame = +2
Query: 78 VFAGKIVPKSLLLKPHQREKMSMEISIHRSLAHQHVVGFHGFFEDNDFVFVVXXXXXXXX 137
VF GK+ + + +K R+ +I R L H +++ F G ++
Sbjct: 353 VFLGKLCAEEVAVK-KVRDIKETDIRNLRKLNHPNIISFKGVCTQAPCYCIIMEYCPYGQ 529
Query: 138 XXXXHKRRKALTEPEARYYLRQIVLGCQYLHRNRVIHRDLKLGNLFLNEDLEVKIGDFGL 197
+ K + + +QI G YLH +++IHRDLK N+ + ++ VKI DFG
Sbjct: 530 LYEVLRDGKEIPPALVLDWSKQIASGMNYLHSHKIIHRDLKSPNVLVAKNDVVKISDFGT 709
Query: 198 A 198
+
Sbjct: 710 S 712
>18401
Length = 463
Score = 48.9 bits (115), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 25/62 (40%), Positives = 36/62 (58%)
Frame = -3
Query: 210 TLCGTPNYIAPEVLSKKGHSFEVDVWSIGCIMYTLLVGKPPFETSCLKETYLRIKKNEYS 269
T+ T +Y APEV+ + G S DVWS+GCIM+ L G F+T KE +++ S
Sbjct: 455 TIVSTRHYRAPEVILELGWSHPCDVWSVGCIMFELYTGYTLFQTHDNKEHLAMMERILGS 276
Query: 270 IP 271
+P
Sbjct: 275 LP 270
>14477
Length = 493
Score = 48.5 bits (114), Expect = 7e-06, Method: Composition-based stats.
Identities = 36/141 (25%), Positives = 60/141 (42%), Gaps = 1/141 (0%)
Frame = -1
Query: 59 LGKGGFAKCFE-ISDADTKEVFAGKIVPKSLLLKPHQREKMSMEISIHRSLAHQHVVGFH 117
LG G F + + D +E+ V K+ L P + ++ E + + + H H+V
Sbjct: 466 LGAGNFGSVMKGVCRLDDREIPVAIKVLKNADLDPSVQSELIKEAEVMKKMDHMHIVRLI 287
Query: 118 GFFEDNDFVFVVXXXXXXXXXXXXHKRRKALTEPEARYYLRQIVLGCQYLHRNRVIHRDL 177
G E + V+ K K L + Q+ G +YL N+ +HRDL
Sbjct: 286 GLCEGETMMLVLELAKLGPLNKFLPKN-KHLPLWNILELMWQVSQGMEYLEANKFVHRDL 110
Query: 178 KLGNLFLNEDLEVKIGDFGLA 198
N+ L ++ KI DFG++
Sbjct: 109 AARNILLCDEHFAKISDFGMS 47
>31489
Length = 329
Score = 42.4 bits (98), Expect(2) = 7e-06, Method: Compositional matrix adjust.
Identities = 19/38 (50%), Positives = 25/38 (65%)
Frame = +3
Query: 146 KALTEPEARYYLRQIVLGCQYLHRNRVIHRDLKLGNLF 183
+ LTE RY+L QI+ G +Y+H V+HRDLK NL
Sbjct: 150 QPLTEEHIRYFLYQILRGLKYIHSANVVHRDLKPSNLL 263
Score = 25.8 bits (55), Expect(2) = 7e-06, Method: Composition-based stats.
Identities = 10/18 (55%), Positives = 13/18 (72%)
Frame = +2
Query: 184 LNEDLEVKIGDFGLATKV 201
+NED V+IGD G+A V
Sbjct: 263 VNEDCHVRIGDLGMARGV 316
>11780
Length = 1713
Score = 48.5 bits (114), Expect = 8e-06, Method: Compositional matrix adjust.
Identities = 49/197 (24%), Positives = 80/197 (40%), Gaps = 6/197 (3%)
Frame = +3
Query: 56 GRFLGKGGFAKCFEISDADTKEVFAGK-IVPKSLLLKPHQREKMSMEISIHRSLAHQHVV 114
G +GKG F + K ++ G+ + K L K + E S+ SL H ++V
Sbjct: 612 GEAIGKGDFGDVY-------KGMYRGQPVAIKQLKDKDRGEQSFLQEASVMTSLRHDNLV 770
Query: 115 GFHGFFEDNDFVFVVXXXXXXXXXXXXHKR-RKALTEPEARYYLRQIVLGCQYLHRNRVI 173
G V R R +T+ + + +YL R++
Sbjct: 771 RLIGVVLGETIFLVTEFMGKGNLVEYLRSRGRSVITKKDQINFATDTCAAMEYLESKRLV 950
Query: 174 HRDLKLGNLFLNEDLEVKIGDFGLATKVEYDGERKKTLCGTP-NYIAPEVLSKKG---HS 229
HRDL N+ +++D + K+ DFGLA G+ +T P + APE L +
Sbjct: 951 HRDLAARNVLVHDDGKAKVSDFGLAKF----GDFSQTSVKFPIKWTAPEALRENKIH*QV 1118
Query: 230 FEVDVWSIGCIMYTLLV 246
V++W I +M LL+
Sbjct: 1119RHVELWHI--VMGNLLL 1163
Score = 32.3 bits (72), Expect = 0.50, Method: Compositional matrix adjust.
Identities = 16/70 (22%), Positives = 35/70 (50%), Gaps = 2/70 (2%)
Frame = +1
Query: 233 DVWSIGCIMYTLL-VGKPPFETSCLKETYLRIKKN-EYSIPKHINPVAASLIQKMLQTDP 290
D+WS G +++ + G+ P+ L + + +++ P+ P S++++ + DP
Sbjct: 1120 DMWSFGILLWEIYSFGRVPYPRIPLTDVVMHVERGYRMEAPEGCPPEIYSIMKQAWELDP 1299
Query: 291 TARPTINELL 300
RPT +L
Sbjct: 1300 NERPTFKSVL 1329
>37602
Length = 804
Score = 48.5 bits (114), Expect = 8e-06, Method: Compositional matrix adjust.
Identities = 21/48 (43%), Positives = 31/48 (64%)
Frame = -1
Query: 148 LTEPEARYYLRQIVLGCQYLHRNRVIHRDLKLGNLFLNEDLEVKIGDF 195
LTEP+ + R+ + G YLHR +HRD+K N+ L E+ +VK+ DF
Sbjct: 228 LTEPQIAFVCRETLKGLHYLHRRGKMHRDIKGANILLTEEGDVKLADF 85
>31120
Length = 439
Score = 44.3 bits (103), Expect = 2e-04, Method: Composition-based stats.
Identities = 23/79 (29%), Positives = 43/79 (54%), Gaps = 4/79 (5%)
Frame = +1
Query: 233 DVWSIGCIMYTLLVGKPPFETSCLKETYLRIKKNEYSIPKH----INPVAASLIQKMLQT 288
D WS+G I++ +L GK PF+ S L + + +YS + ++P A S + +L+
Sbjct: 40 DAWSLGVILFIMLNGKMPFDDSNLNKLLEDQRSKKYSFRRKLQDLVSPNARSTVSVLLEP 219
Query: 289 DPTARPTINELLNDEFFTS 307
+ R +NE+LN ++ +
Sbjct: 220 NSAMRWDLNEVLNCQWLQT 276
>17975
Length = 449
Score = 42.7 bits (99), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 24/54 (44%), Positives = 31/54 (57%), Gaps = 1/54 (1%)
Frame = +3
Query: 147 ALTEPEARYYLRQIVLGCQYLHRNRVIHRDLKLGN-LFLNEDLEVKIGDFGLAT 199
L E A+ Y RQIV Y H+ V+HRDLK N +F + VK+ DFG +T
Sbjct: 255 GLEEKLAKRYFRQIVEAISYCHKLHVVHRDLKPENVVFFEKPGLVKLTDFGFST 416
>28157
Length = 400
Score = 40.8 bits (94), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 30/101 (29%), Positives = 46/101 (45%), Gaps = 6/101 (5%)
Frame = +3
Query: 108 LAHQHVVGFHGFFEDNDFVFVVXXXXXXXXXXXXHKR--RKALTEPEARYYLRQIVLGCQ 165
++H ++V +G D+ V+ H + T A +L Q LG +
Sbjct: 81 VSHPNIVCLYGACRDHPVCLVMEYAEGGSLYNVLHGSGPQPQYTAAHAMNWLLQCALGVE 260
Query: 166 YLHRNR---VIHRDLKLGNLFLNE-DLEVKIGDFGLATKVE 202
YLH + +IHRDLK NL L + ++KI DFG A +
Sbjct: 261 YLHGMKPKALIHRDLKPPNLLLIQCGTKLKICDFGTACDIH 383
>18996
Length = 491
Score = 40.8 bits (94), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 40/143 (27%), Positives = 66/143 (46%), Gaps = 14/143 (9%)
Frame = +2
Query: 173 IHRDLKLGNLFLNEDLEVKIGDFGLATKVEYDG------ERKKTLCGTPNYIAPEVLSKK 226
IHRDL N+ ++ VKI DFGLA DG +R + + +PE +
Sbjct: 2 IHRDLAARNILVDRSC-VKISDFGLAQFANADGYYYGISQRDIPI----KWYSPEAIETC 166
Query: 227 GHSFEVDVWSIGCIMYTLLV-GKPPF---ETSCLKETYL-RIKKNEYSIPKH---INPVA 278
S DVWS G ++ + G+ P +E +L R++K E +PK + V
Sbjct: 167 KFSSYSDVWSYGVTLFEMFSRGEIPNLLPGHDLTQEEFLNRLRKGE-RLPKPELCSDFVY 343
Query: 279 ASLIQKMLQTDPTARPTINELLN 301
+ L++ P +RPT ++++
Sbjct: 344 SELMRPCWHEMPKSRPTFHQIIQ 412
>17516
Length = 453
Score = 40.4 bits (93), Expect = 0.002, Method: Composition-based stats.
Identities = 19/40 (47%), Positives = 28/40 (70%), Gaps = 1/40 (2%)
Frame = -3
Query: 210 TLCGTPNYIAPEVLSKKG-HSFEVDVWSIGCIMYTLLVGK 248
TL GTP Y+APEVL +KG + + DV+S+ I++ L G+
Sbjct: 442 TLAGTPVYMAPEVLLQKGQYDMKADVYSLAIILWELWYGQ 323
>07836
Length = 1478
Score = 35.8 bits (81), Expect = 0.052, Method: Compositional matrix adjust.
Identities = 26/85 (30%), Positives = 42/85 (49%), Gaps = 12/85 (14%)
Frame = -1
Query: 172 VIHRDLKLGNLFLNEDLEVKIGDFGLATKVEYDGERKKTLC------GTPNYIAPEVLS- 224
+ HRD+K N+ + ++ I D GLA V Y E + GT Y+APEVL
Sbjct: 1169 IAHRDIKSKNILVKKNGTCCIADLGLA--VRYISESNEVDVAPNPRQGTKRYMAPEVLEM 996
Query: 225 ----KKGHSF-EVDVWSIGCIMYTL 244
K +F + D+++ G +M+ +
Sbjct: 995 LLNVKNFDAFKQADMYAFGLVMWEI 921
>17253
Length = 483
Score = 35.8 bits (81), Expect = 0.057, Method: Composition-based stats.
Identities = 27/121 (22%), Positives = 53/121 (43%), Gaps = 13/121 (10%)
Frame = -1
Query: 94 QREKMSMEISIHRSLA-HQHVVGFHGFFEDNDFVFVVXXXXXXXXXXXXHKRRKA----- 147
++ + E+SI R L H +VV F G +D ++ ++R+
Sbjct: 420 EKSEFLRELSIMRKLPRHPNVVSFMGCCTMSDPALILMEFCCHGDLLSFLRKRRPDRTVF 241
Query: 148 -------LTEPEARYYLRQIVLGCQYLHRNRVIHRDLKLGNLFLNEDLEVKIGDFGLATK 200
LT + + + G ++ N+++HRD+ N+ ++E K+ DFGL+ +
Sbjct: 240 LTSTANDLTARDFFSFALHVARGMAHVANNKIVHRDVAARNVLISERNVCKVSDFGLSRR 61
Query: 201 V 201
V
Sbjct: 60 V 58
>26009
Length = 886
Score = 35.4 bits (80), Expect = 0.068, Method: Compositional matrix adjust.
Identities = 13/42 (30%), Positives = 26/42 (61%)
Frame = +3
Query: 143 KRRKALTEPEARYYLRQIVLGCQYLHRNRVIHRDLKLGNLFL 184
+R KA EA+ ++Q+V ++H +++HRD+K N+ +
Sbjct: 687 RRNKACGSREAKSVMKQLVSALDFMHSKQLVHRDIKPENVLI 812
>32000
Length = 644
Score = 35.4 bits (80), Expect = 0.071, Method: Compositional matrix adjust.
Identities = 21/58 (36%), Positives = 30/58 (51%), Gaps = 1/58 (1%)
Frame = -1
Query: 189 EVKIGDFGLATKVEYDGERKKTLCGTPNYIAPEVL-SKKGHSFEVDVWSIGCIMYTLL 245
++KI DFGLA T Y APE+L + +S VD+WS+GCI ++
Sbjct: 575 KMKIADFGLARVFGLPVRTYTHEVITLWYRAPEILLGCRFYSVPVDIWSLGCIFVEMM 402
>13078
Length = 773
Score = 35.0 bits (79), Expect = 0.084, Method: Compositional matrix adjust.
Identities = 19/45 (42%), Positives = 25/45 (55%)
Frame = -1
Query: 227 GHSFEVDVWSIGCIMYTLLVGKPPFETSCLKETYLRIKKNEYSIP 271
G S DVWSIGCIM+ L G F+T KE +++ S+P
Sbjct: 749 GWSQPCDVWSIGCIMFELYTGYTLFQTHDNKEHLAMMERILGSLP 615
>16708
Length = 1397
Score = 35.0 bits (79), Expect = 0.099, Method: Compositional matrix adjust.
Identities = 36/155 (23%), Positives = 63/155 (40%), Gaps = 20/155 (12%)
Frame = -1
Query: 159 QIVLGCQYLHRNRVIHRDLKLGNLFLNEDLEVKIGDFGLA---------TKVEYDGERKK 209
Q V +++H V+H D+K N+ ++ K+ D+G+A T+ G K
Sbjct: 1070 QXVCALEHIHELGVVHMDVKADNVLVDAHGNCKLTDYGIAQLYKVYPAPTETHSSGCTNK 891
Query: 210 TLCGT--PNYIAP-EVLSKKGHSFEVDVWSIGCIMYTL--------LVGKPPFETSCLKE 258
T P + P E S++G D + +G +++TL V +PP
Sbjct: 890 RTFYTRPPATMTPSERFSEEGDGIGTDYFRLGQMLWTLTGAVLLHVWVSRPP-----KLP 726
Query: 259 TYLRIKKNEYSIPKHINPVAASLIQKMLQTDPTAR 293
+ R ++E S + I+K+ DP R
Sbjct: 725 DWCRTPESELS-------GMSDFIEKLCHGDPNMR 642
>27274
Length = 396
Score = 34.3 bits (77), Expect = 0.15, Method: Composition-based stats.
Identities = 14/32 (43%), Positives = 21/32 (65%)
Frame = -1
Query: 221 EVLSKKGHSFEVDVWSIGCIMYTLLVGKPPFE 252
E+L + H VD+WS+G +++ LL G PFE
Sbjct: 375 ELLRGQQHGPTVDMWSLGILLHELLSGHVPFE 280
>17722
Length = 680
Score = 33.9 bits (76), Expect = 0.22, Method: Compositional matrix adjust.
Identities = 16/62 (25%), Positives = 29/62 (46%)
Frame = -3
Query: 232 VDVWSIGCIMYTLLVGKPPFETSCLKETYLRIKKNEYSIPKHINPVAASLIQKMLQTDPT 291
VD W G +MY ++ G+ PF + I P++++ A +L+ +L +P
Sbjct: 678 VDWWGTGVVMYEMMCGRLPFYNRDHDVLFELILLQNVKFPRNLSEEAKTLLSGLLAKNPK 499
Query: 292 AR 293
R
Sbjct: 498 RR 493
>03106
Length = 2384
Score = 31.6 bits (70), Expect = 1.1, Method: Compositional matrix adjust.
Identities = 18/69 (26%), Positives = 30/69 (43%), Gaps = 4/69 (5%)
Frame = +2
Query: 231 EVDVWSIGCIMYTLLVGKPPF----ETSCLKETYLRIKKNEYSIPKHINPVAASLIQKML 286
+ DVW+ G + Y + PF +++C + L S+P L+ ML
Sbjct: 26 KADVWAAGAVAYEIFGASNPFYSRLDSACYSQHDLP------SLPGDTPEGVVRLVTSML 187
Query: 287 QTDPTARPT 295
+ DP RP+
Sbjct: 188 ERDPAQRPS 214
>16350
Length = 1108
Score = 30.8 bits (68), Expect = 1.8, Method: Compositional matrix adjust.
Identities = 25/91 (27%), Positives = 36/91 (39%)
Frame = +2
Query: 187 DLEVKIGDFGLATKVEYDGERKKTLCGTPNYIAPEVLSKKGHSFEVDVWSIGCIMYTLLV 246
D VKI D G A + T Y EVL G+ D+WS C+ + L
Sbjct: 347 DFPVKIADLGNACWTYHHFTEDIQ---TRQYRCLEVLIGAGYGTPADIWSTACMAFELAT 517
Query: 247 GKPPFETSCLKETYLRIKKNEYSIPKHINPV 277
G FE E Y R + + + + + P+
Sbjct: 518 GDYLFEPHS-GEDYSRDEDHLAHVIELVGPI 607
>23319
Length = 2235
Score = 30.0 bits (66), Expect = 3.0, Method: Compositional matrix adjust.
Identities = 14/33 (42%), Positives = 19/33 (57%), Gaps = 1/33 (3%)
Frame = +3
Query: 220 PEVLSKKGHSFEVDVWSIGCIMYTLL-VGKPPF 251
P+V K +S +D+WS GCI L G+P F
Sbjct: 3 PDVYXAKMYSTSIDMWSAGCIFAELANAGRPLF 101
>29722
Length = 352
Score = 29.3 bits (64), Expect = 4.7, Method: Compositional matrix adjust.
Identities = 11/25 (44%), Positives = 16/25 (64%)
Frame = -3
Query: 281 LIQKMLQTDPTARPTINELLNDEFF 305
L++ ML DP RP+IN +L D +
Sbjct: 254 LLRAMLYQDPAKRPSINRILRDPYI 180
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000338413 | hsapiens_gene_ensembl |
Ubiquitin-activating enzyme E1 (A1S9 protein).
[Source:Uniprot/SWISSPROT;Acc:P22314]
(1058 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
34235 226 e-100
19711 170 8e-86
21876 290 2e-78
25566 257 2e-68
00369 118 1e-26
21008 117 3e-26
06604 117 3e-26
20367 75 1e-13
14935 40 0.007
>34235
Length = 1026
Score = 226 bits (575), Expect(3) = e-100, Method: Compositional matrix adjust.
Identities = 110/194 (56%), Positives = 133/194 (68%), Gaps = 1/194 (0%)
Frame = -1
Query: 741 FWSGPKRCPHPLTFDVNNPLHLDYVMAAANLFAQTYGLTGSQDRAAVATFLQSVQVPEFT 800
FWSGPKRCPH L FD +N LHLDY+ AAAN+ GL +DRAA+ + V VPEF
Sbjct: 876 FWSGPKRCPHALEFDADNELHLDYIEAAANMKGFMCGLPPVRDRAAIKDMVSKVMVPEFV 697
Query: 801 PKSGVKIHVSDQELQSANA-SVDDSRLEELKATLPSPDKLPGFKMYPIDFEKDDDSNFHM 859
P+SG+KI V+D E Q+ N + D +E+LK+ LPSPD+L G ++ +DFEKDDD+NFHM
Sbjct: 696 PRSGIKIAVTDAEAQAGNNDNFDKDTVEKLKSALPSPDELKGRQLNAVDFEKDDDTNFHM 517
Query: 860 DFIVAASNLRAENYDIPSADRHKSKLXXXXXXXXXXXXXXXVVGLVCLELYKVVQGHRQL 919
DFI AASNLRAENY IP ADRHKSKL VVGLV LEL K+ QGH +
Sbjct: 516 DFITAASNLRAENYSIPPADRHKSKLIAGRIIPAIATTTAMVVGLVGLELIKLAQGHTNV 337
Query: 920 DSYKNGFLNLALPF 933
+ +KNGF NLALP
Sbjct: 336 ERFKNGFANLALPL 295
Score = 125 bits (313), Expect(3) = e-100, Method: Compositional matrix adjust.
Identities = 63/107 (58%), Positives = 81/107 (75%)
Frame = -2
Query: 931 LPFFGFSEPLAAPRHQYYNQEWTLWDRFEVQGLQPNGEEMTLKQFLDYFKTEHKLEITML 990
L F FSEP+ AP+ +YY +E+TLWDRF VQG E+TL+QFLDYF+ EH LEITML
Sbjct: 305 LSLFAFSEPILAPKSKYYEKEFTLWDRFTVQG------EITLQQFLDYFQKEHGLEITML 144
Query: 991 SQGVSMLYSFFMPAAKLKERLDQPMTEIVSRVSKRKLGRHVRALVLE 1037
SQGV +L+S FM AK +ER + ++E+V +VSK+K+ HVRALVLE
Sbjct: 143 SQGVCLLFSNFMQPAKQEERKNLLISELVKKVSKKKIPPHVRALVLE 3
Score = 57.0 bits (136), Expect(3) = e-100, Method: Compositional matrix adjust.
Identities = 25/41 (60%), Positives = 30/41 (73%)
Frame = -3
Query: 706 CVTWACHHWHTQYSNNIRQLLHNFPPDQLTSSGAPFWSGPK 746
CV WA + + T YSN I+QLL NFP DQ+TSSGAPF G +
Sbjct: 982 CVEWARNLFQTNYSNQIKQLLFNFPSDQMTSSGAPFLVGSQ 860
>19711
Length = 1114
Score = 170 bits (430), Expect(2) = 8e-86, Method: Compositional matrix adjust.
Identities = 84/171 (49%), Positives = 109/171 (63%), Gaps = 2/171 (1%)
Frame = +3
Query: 200 CDFGEEMILTDSNGEQPLSAMVSMVTKDNPGVVTCLDEARHGFESGDFVSFSEVQGMVEL 259
CDFG+ + D GE+ ++ +TK NPGVVTCLD HG E+GD V+F EV+GM +L
Sbjct: 3 CDFGDTFEVMDPTGEEAKEVFIANITKANPGVVTCLDNLLHGLETGDLVTFKEVKGMEQL 182
Query: 260 NGNQPMEIKVLGPYTFSICDTSN--FSDYIRGGIVSQVKVPKKISFKSLVASLAEPDFVV 317
N Q IKVL P TFSIC+TS F Y GGI+SQVKVPK + FKSL L P ++
Sbjct: 183 NSQQ-CAIKVLSPTTFSICNTSGSEFGAYESGGIISQVKVPKSVHFKSLEEQLVSPSLLM 359
Query: 318 TDFAKFSRPAQLHIGFQALHQFCAQHGRPPRPRNEEDAAELVALAQAVNAR 368
D KF+ P +H+ FQALHQF A+ G P+P + A +V LA+A +A+
Sbjct: 360 PDLCKFTAPGNIHVAFQALHQFWAETGSLPQPWCSDSADRMVLLAKACSAK 512
Score = 166 bits (421), Expect(2) = 8e-86, Method: Compositional matrix adjust.
Identities = 85/196 (43%), Positives = 120/196 (61%), Gaps = 1/196 (0%)
Frame = +2
Query: 372 AVQQNNLDEDLIRKLAYVAAGDLAPINAFIGGLAAQEVMKACSGKFMPIMQWLYFDALEC 431
+ ++E ++R L++ A G LAP+ A +GG+ AQE +KA +GKF+P+ QWLY DA+E
Sbjct: 527 GTEAEEVEEKIVRCLSHTARGSLAPLCAAMGGIVAQEGLKALTGKFLPLSQWLYLDAMET 706
Query: 432 LPEDKEVLTEDKCLQRQNRYDGQVAVFGSDLQEKLGKQKYFLVGAGAIGCELLKNFAMXX 491
+PE V + + R +R D G D+ +KL + F+VG GAIGCE+LKN+A+
Sbjct: 707 IPE-LSVTSPEAFQLRNDRLDPLRICVGEDVCQKLADTRLFMVGCGAIGCEMLKNYALLG 883
Query: 492 XXXXXXXXXXVTDMDTIEKSNLNRQFLFRPWDVTKLKSDTAAAAVRQMNPHIRVTSHQNR 551
+TD D IEKSNLNRQFLFR + K KS TAA +V +NP + + + QN+
Sbjct: 884 LGAGQKGQITITDNDLIEKSNLNRQFLFRSHHIQKPKSTTAAQSVLDINPALHIQAQQNK 1063
Query: 552 VGPDTERI-YDDDFFQ 566
V P TE Y D FF+
Sbjct: 1064VCPQTESTHYPDAFFE 1111
>21876
Length = 894
Score = 290 bits (743), Expect = 2e-78, Method: Compositional matrix adjust.
Identities = 153/305 (50%), Positives = 204/305 (66%), Gaps = 9/305 (2%)
Frame = -1
Query: 44 NGSEADIDEGLYSRQLYVLGHEAMKR---LQTSSVLVSGLRGLGVEIAKNIILGGVKAVT 100
NG+ DIDEGL GHEAM++ LQ S + G GLG+EIAKN++LGGVK+V+
Sbjct: 894 NGAADDIDEGLVXSPAVCAGHEAMRKMAKLQCSDLWAMG--GLGIEIAKNVVLGGVKSVS 721
Query: 101 LHDQGTAQWADLSSQFYLREEDIGKNRAEVSQPRLAELNSYVPVTAYTGPLVEDFLSGFQ 160
+HD G + DLSSQF+LR+ED+GKNRAEVSQPRLAELNSYVP+++ TG DF G
Sbjct: 720 IHDPGKVVFGDLSSQFFLRDEDVGKNRAEVSQPRLAELNSYVPISSSTG----DFG*GLL 553
Query: 161 VVVLTNTPLEDQLRV------GEFCHNRGIKLVVADTRGLFGQLFCDFGEEMILTDSNGE 214
V V + DQL V G ++ + DFG ++TD +GE
Sbjct: 552 VQVSGGS--TDQLFVR*TDPCGRVLSLSQHQVHCGRNAWTVWENLLDFGSNFVITDGDGE 379
Query: 215 QPLSAMVSMVTKDNPGVVTCLDEARHGFESGDFVSFSEVQGMVELNGNQPMEIKVLGPYT 274
QP+S M++ + K + VV +DE +HG E GD+V+F EVQGM ELNG +P++IKVLGPYT
Sbjct: 378 QPISCMIADIEKGDNSVVATVDETKHGLEDGDYVTFKEVQGMTELNGCKPVKIKVLGPYT 199
Query: 275 FSICDTSNFSDYIRGGIVSQVKVPKKISFKSLVASLAEPDFVVTDFAKFSRPAQLHIGFQ 334
FSI DT+ ++DYIRGG +QVK+PK I+FKS+ A++ P+ + +DFAKF RP QLHI F+
Sbjct: 198 FSIGDTTKYADYIRGGTATQVKMPKTINFKSIKAAMDAPEILPSDFAKFDRPPQLHIAFK 19
Query: 335 ALHQF 339
AL ++
Sbjct: 18 ALSEY 4
>25566
Length = 1639
Score = 257 bits (657), Expect = 2e-68, Method: Compositional matrix adjust.
Identities = 171/467 (36%), Positives = 247/467 (52%), Gaps = 11/467 (2%)
Frame = +2
Query: 600 TLGTKGNVQVVIPFLTESYSSSQDPPEKSIPICTLKNFPNAIEHTLQWARDEFEGLFKQP 659
T+GTKG+VQV+IP LTESY+S QDP ++ P CT+K+FP IEH +QWARD+FE L+
Sbjct: 2 TMGTKGHVQVIIPHLTESYTSQQDPADEDYPYCTVKSFPATIEHCIQWARDKFEELYVNQ 181
Query: 660 AENVNQYLTDPKFVERTLRLAGTQPLEVLEAVQR--SLVLQRPQTWADCVTWACHHWHTQ 717
N++L + T + + +V++ R + RP +W DCV A +
Sbjct: 182 PNLFNKFLASN--ADMTAVVHKLKSGDVVDGGLRVSKMAATRPHSWEDCVRLARIRFEKY 355
Query: 718 YSNNIRQLLHNFPPDQLTSSGAPFWSGPKRCPHPLTFDVNNPLHLDYVMAAANLFAQTYG 777
+++ RQLLH FP D + FW PKR P PL F+ ++PLH+ +V + A L Y
Sbjct: 356 FNHKARQLLHAFPLDIKLPDNSLFWQSPKRPPTPLQFNADDPLHMTFVTSTARLLCDIYA 535
Query: 778 LTGSQDRA--AVATFLQSVQVPEFTPKSGVKIHVSDQ------ELQSANASVDDSRLEEL 829
++ S + ++ T L +V VP F P S KI + E QS+ V +
Sbjct: 536 ISYSTQVSTDSIKTILHAVTVPAFVP-SDKKIETDETKSQQEAEPQSSGDEVTAAGERLA 712
Query: 830 KATLPSPDKLPGFKMYPIDFEKDDDSNFHMDFIVAASNLRAENYDIPSADRHKSKLXXXX 889
+ + S + M ++FEKDDDSN H++FI A SN+RA+ Y I + DR K K
Sbjct: 713 QVVMSSQAQSALQPMAALEFEKDDDSNDHINFIAACSNMRAQMYSIENVDRLKIKRIAGR 892
Query: 890 XXXXXXXXXXXVVGLVCLELYKVVQGHRQLDSYKNGFLNLALPFFGFSEPLAAPRHQYYN 949
V GLV +EL KV+Q R LD++KN FLNLALP SEP A R
Sbjct: 893 IVPAIATTTAAVSGLVTIELIKVLQ-QRPLDAFKNAFLNLALPMLLLSEPGACARKVLKE 1069
Query: 950 Q-EWTLWDRFEVQGLQPNGEEMTLKQFLDYFKTEHKLEITMLSQGVSMLYSFFMPAAKLK 1008
++WD++ ++G Q + TL+QFLD K E T + GV ++Y MP K
Sbjct: 1070 GLSVSVWDKWTIRGKQ----DFTLQQFLDSCKDSFGFEATAVVNGVKIIYMPIMPPH--K 1231
Query: 1009 ERLDQPMTEIVSRVSKRKLGRHVRALVLELCCNDESGEDVEVPYVRY 1055
+RL Q M +++ K + + L +C D+ GE++E P VRY
Sbjct: 1232 KRLPQTMMKLI------KPEPGITYVDLVVCFEDDKGEEIEGPPVRY 1354
>00369
Length = 1082
Score = 118 bits (296), Expect = 1e-26, Method: Compositional matrix adjust.
Identities = 70/207 (33%), Positives = 108/207 (52%), Gaps = 14/207 (6%)
Frame = +3
Query: 470 KYFLVGAGAIGCELLKNFAMXXXXXXXXXXXXVTDMDTIEKSNLNRQFLFRPWDVTKLKS 529
K ++GAG +GCELLK+ A+ V DMDTI+ SNLNRQFLFRP DV K+
Sbjct: 222 KLLVIGAGGLGCELLKDLALMGFFDIH-----VIDMDTIDVSNLNRQFLFRPKDVGSPKA 386
Query: 530 DTAAAAVRQMNPHIRVTSHQNRVGPDTERIYDDDFFQNLDGVANALDNVDARMYMDRRCV 589
+ AAA + P +VT H ++ + YD+ F++ + LD++ AR +++ +
Sbjct: 387 EVAAAFINSRVPGCKVTPHFAKI-----QDYDESFYRGFHVIVCGLDSIIARRWINSMLI 551
Query: 590 YYRK------------PLLESGTLGTKGNVQVVIPFLTESYSSSQD--PPEKSIPICTLK 635
PL++ GT G KGN +VV+P +T + D PP+ + P+CT+
Sbjct: 552 SLLNYEDGELDQSSIIPLVDGGTEGFKGNARVVLPGITACIECTLDLYPPQVNFPLCTIA 731
Query: 636 NFPNAIEHTLQWARDEFEGLFKQPAEN 662
+ P EH +++ R + P EN
Sbjct: 732 HTPRLPEHCIEYVR-----ILLWPKEN 797
Score = 51.2 bits (121), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 34/99 (34%), Positives = 50/99 (50%), Gaps = 6/99 (6%)
Frame = +3
Query: 71 QTSSVLVSGLRGLGVEIAKNIILGGVKAVTLHDQGTAQWADLSSQFYLREEDIGKNRAEV 130
+T +LV G GLG E+ K++ L G + + D T ++L+ QF R +D+G +AEV
Sbjct: 213 ETCKLLVIGAGGLGCELLKDLALMGFFDIHVIDMDTIDVSNLNRQFLFRPKDVGSPKAEV 392
Query: 131 SQPRLAELNSYVPVTAYTGPLV------EDFLSGFQVVV 163
+ A +NS VP T E F GF V+V
Sbjct: 393 AA---AFINSRVPGCKVTPHFAKIQDYDESFYRGFHVIV 500
>21008
Length = 408
Score = 117 bits (293), Expect = 3e-26, Method: Compositional matrix adjust.
Identities = 63/128 (49%), Positives = 84/128 (65%), Gaps = 2/128 (1%)
Frame = +3
Query: 19 PGSNCSPAQSVLSEVPSVPTNGMAKNGSEADIDEGLYSRQLYVLGHEAMKRLQTSSVLVS 78
PG NC ++ T MA S+ +ID+ LYSRQ YVLG AMKR+ SSVL+
Sbjct: 54 PGFNCF-------KINLCNTETMA---SDMEIDDSLYSRQRYVLGDSAMKRMAQSSVLIH 203
Query: 79 GLRGLGVEIAKNIILGGVKAVTLHDQGTAQWADLSSQFYLREEDI--GKNRAEVSQPRLA 136
GL GLG+EIAKNI+L GVK++T+ D T+ +DL +QF++R+ D+ KNRAE +LA
Sbjct: 204 GLGGLGIEIAKNIVLAGVKSLTVQDSKTSCTSDLGTQFFVRQADVDAAKNRAEACAGKLA 383
Query: 137 ELNSYVPV 144
ELN YV +
Sbjct: 384 ELNPYVKI 407
>06604
Length = 1748
Score = 117 bits (292), Expect = 3e-26, Method: Compositional matrix adjust.
Identities = 62/153 (40%), Positives = 89/153 (58%), Gaps = 3/153 (1%)
Frame = -2
Query: 54 LYSRQLYVLGHEAMKRLQTSSVLVSGLRGLGVEIAKNIILGGVKAVTLHDQGTAQWADLS 113
LY RQ+ + G +A +RL+ +SVL+ G+RGLG E+AKNI+L G+K++TL D A D +
Sbjct: 1732 LYDRQIRLWGLDAQRRLRAASVLLVGVRGLGAEVAKNIVLAGIKSLTLLDPSLADEEDTA 1553
Query: 114 SQFYLREEDIGKNRAEVSQPRLAELNSYVPVTAYTGPL---VEDFLSGFQVVVLTNTPLE 170
+QF + +IGKNRAE S R LN V VTA T + +DF++ F VV T +
Sbjct: 1552 AQFLIPRSEIGKNRAEASLERTQLLNPMVTVTADTCSIDDKDDDFVTSFDVVCATGCGVS 1373
Query: 171 DQLRVGEFCHNRGIKLVVADTRGLFGQLFCDFG 203
R+ C + G+ D G +G +F D G
Sbjct: 1372 TLRRLDRVCRDAGVMFYAGDVFGFYGYMFADLG 1274
Score = 43.5 bits (101), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 33/138 (23%), Positives = 56/138 (40%)
Frame = -2
Query: 451 YDGQVAVFGSDLQEKLGKQKYFLVGAGAIGCELLKNFAMXXXXXXXXXXXXVTDMDTIEK 510
YD Q+ ++G D Q +L LVG +G E+ KN + + D +
Sbjct: 1729 YDRQIRLWGLDAQRRLRAASVLLVGVRGLGAEVAKNIVLAGIKSLTLLDPSLAD-----E 1565
Query: 511 SNLNRQFLFRPWDVTKLKSDTAAAAVRQMNPHIRVTSHQNRVGPDTERIYDDDFFQNLDG 570
+ QFL ++ K +++ + + +NP + VT+ + DDDF + D
Sbjct: 1564 EDTAAQFLIPRSEIGKNRAEASLERTQLLNPMVTVTADTCSIDDK-----DDDFVTSFDV 1400
Query: 571 VANALDNVDARMYMDRRC 588
V V +DR C
Sbjct: 1399 VCATGCGVSTLRRLDRVC 1346
Score = 38.1 bits (87), Expect = 0.020, Method: Compositional matrix adjust.
Identities = 27/99 (27%), Positives = 48/99 (48%), Gaps = 2/99 (2%)
Frame = -3
Query: 334 QALHQFCAQHGRPPRPRNEE-DAAELVAL-AQAVNARALPAVQQNNLDEDLIRKLAYVAA 391
+AL +F Q R P ++E D +L L Q + + N + ED +
Sbjct: 1044 KALLEFLEQQKRRPATSSQESDCQQLSKLRXQXLZSXG---AGDNKMAEDFTQ----YCF 886
Query: 392 GDLAPINAFIGGLAAQEVMKACSGKFMPIMQWLYFDALE 430
G L+P+ A +GG+ QE++KA S K +P + +++ +
Sbjct: 885 GQLSPVCAVVGGILGQEIIKAVSQKDIPHNNFFFYNGTD 769
>20367
Length = 859
Score = 75.5 bits (184), Expect = 1e-13, Method: Composition-based stats.
Identities = 52/165 (31%), Positives = 76/165 (46%), Gaps = 11/165 (6%)
Frame = -1
Query: 55 YSRQLYVLGHEAMKRLQTSSVLVSGLRGLGVEIAKNIILGGVKAVTLHDQGTAQWADLSS 114
Y RQL + G L+T+ V + G EI KN+IL G+ + T+ D Q D+ +
Sbjct: 814 YDRQLRLWGDHGQSALETARVCLINATATGTEILKNVILPGIGSFTIVDGNKVQGEDVGN 635
Query: 115 QFYLREEDIGKNRAEVSQPRLAELNSYVPVTAYTGPLVE-----------DFLSGFQVVV 163
F+L+ + IGK+RA+V+ L ELN V TG VE DF + F +V+
Sbjct: 634 NFFLQVDSIGKSRAQVATELLGELNDDV-----TGNFVEENVENLLESNADFFTTFSIVI 470
Query: 164 LTNTPLEDQLRVGEFCHNRGIKLVVADTRGLFGQLFCDFGEEMIL 208
TN + L++ I L+V G G L E I+
Sbjct: 469 ATNLHEKTLLQLAGVLWENNIPLLVCRCYGFIGYLRLVLKEHTII 335
Score = 36.2 bits (82), Expect = 0.078, Method: Composition-based stats.
Identities = 29/131 (22%), Positives = 57/131 (43%), Gaps = 3/131 (2%)
Frame = -1
Query: 438 VLTEDKC-LQRQNRYDGQVAVFGSDLQEKLGKQKYFLVGAGAIGCELLKNFAMXXXXXXX 496
++ E K L + N+YD Q+ ++G Q L + L+ A A G E+LKN +
Sbjct: 856 IMAETKTGLDKNNKYDRQLRLWGDHGQSALETARVCLINATATGTEILKNVIL-----PG 692
Query: 497 XXXXXVTDMDTIEKSNLNRQFLFRPWDVTKLKSDTAAAAVRQMNPHIRVTSHQNRVGPDT 556
+ D + ++ ++ F + + K ++ A + ++N + N V +
Sbjct: 691 IGSFTIVDGNKVQGEDVGNNFFLQVDSIGKSRAQVATELLGELNDDVT----GNFVEENV 524
Query: 557 ERIYDD--DFF 565
E + + DFF
Sbjct: 523 ENLLESNADFF 491
>14935
Length = 378
Score = 39.7 bits (91), Expect = 0.007, Method: Compositional matrix adjust.
Identities = 21/62 (33%), Positives = 32/62 (51%), Gaps = 2/62 (3%)
Frame = -2
Query: 614 LTESYSSSQDPPEKSIPICTLKNFPNAIEHTLQWARDEFEGLF--KQPAENVNQYLTDPK 671
LTE Y +KS P CT++N P+ H + WA+ F LF + P ++V+ DP+
Sbjct: 377 LTECYECQPKAAQKSFPGCTIRNTPSEPIHCVVWAKHLFNQLFGEEDPDQDVSPDTEDPE 198
Query: 672 FV 673
Sbjct: 197 LT 192
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000356785 | hsapiens_gene_ensembl | Nucleoside
diphosphate kinase 7 (EC 2.7.4.6) (NDK 7) (NDP kinase 7) (nm23-H7).
[Source:Uniprot/SWISSPROT;Acc:Q9Y5B8]
(376 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
32935 196 e-100
02656 170 9e-43
02733 76 4e-15
14087 35 5e-06
31902 45 5e-05
>32935
Length = 1188
Score = 196 bits (499), Expect(2) = e-100, Method: Compositional matrix adjust.
Identities = 92/150 (61%), Positives = 110/150 (73%), Gaps = 6/150 (4%)
Frame = +1
Query: 232 NTAKFTNCTCCIVKPHAVSEGLLGKILMAIRDAGFEISAMQMFNMDRVNVEEFYEVYKGV 291
NTA NCTCCI+KP A G+ GKI+ AI +AGF + + +MF +++ N EEF EVYKGV
Sbjct: 694 NTASIGNCTCCIIKPSAFKAGVAGKIINAITEAGFRVGSAEMFTLEKANAEEFLEVYKGV 873
Query: 292 VTEYHDMVTEMYSGPCVAMEIQQNNATK------TFREFCGPADPEIARHLRPGTLRAIF 345
V EY MVTE+ SGPC+A+EI + T FRE GP DPEIARHLRP TLRA+F
Sbjct: 874 VHEYPAMVTELTSGPCLALEIVGGSGTNASLLAPAFRELAGPVDPEIARHLRPRTLRAMF 1053
Query: 346 GKTKIQNAVHCTDLPEDGLLEVQYFFKILD 375
G KI+NAVHCTDLP+DG LEV+YFFKILD
Sbjct: 1054GTDKIKNAVHCTDLPDDGPLEVEYFFKILD 1143
Score = 188 bits (477), Expect(2) = e-100, Method: Compositional matrix adjust.
Identities = 93/232 (40%), Positives = 144/232 (62%), Gaps = 6/232 (2%)
Frame = +2
Query: 5 ERFVFIAEWYDPNASLLRRYELLFYPGD---GSV---EMHDVKNHRTFLKRTKYDNLHLE 58
ER+ FI EWYD ++ R++ ++ G V E DV +++ +R + L
Sbjct: 11 ERYSFIVEWYDDMSARTLRFQFFYFTNSQVCGDVRHKEPQDVSANQSERQRAQ----SLR 178
Query: 59 DLFIGNKVNVFSRQLVLIDYGDQYTARQLGSRKEKTLALIKPDAISKAGEIIEIINKAGF 118
+ R L ++DY D+YT R+L S++E+TL LIKPDA+ K G++++ I + GF
Sbjct: 179 PVHWQQHQPPAPRLLTIVDYDDEYTRRKLTSKRERTLGLIKPDAVEKLGQVLDKILQKGF 358
Query: 119 TITKLKMMMLSRKEALDFHVDHQSRPFFNELIQFITTGPIIAMEILRDDAICEWKRLLGP 178
I++L+M L R AL+F+ +H+S+PF N L+ ++T+GP++A EI+ ++A+ W+ +GP
Sbjct: 359 LISRLRMCKLDRNTALEFYQEHRSKPFLNALLDYVTSGPVVAFEIVGENAVGAWREAIGP 538
Query: 179 ANSGVARTDASESIRALFGTDGIRNAAHGPDSFASAAREMELFFPSSGGCGP 230
+ +AR +A SIRA +GTD NA HG DS SAARE+E FFPSSG P
Sbjct: 539 TDPSLARKEAPTSIRAQYGTDVTCNAVHGSDSPGSAAREVEFFFPSSGSHSP 694
Score = 88.6 bits (218), Expect = 4e-18, Method: Compositional matrix adjust.
Identities = 54/134 (40%), Positives = 73/134 (54%), Gaps = 2/134 (1%)
Frame = +2
Query: 240 TCCIVKPHAVSEGLLGKILMAIRDAGFEISAMQMFNMDRVNVEEFYEVY--KGVVTEYHD 297
T ++KP AV + LG++L I GF IS ++M +DR EFY+ + K + D
Sbjct: 284 TLGLIKPDAVEK--LGQVLDKILQKGFLISRLRMCKLDRNTALEFYQEHRSKPFLNALLD 457
Query: 298 MVTEMYSGPCVAMEIQQNNATKTFREFCGPADPEIARHLRPGTLRAIFGKTKIQNAVHCT 357
VT SGP VA EI NA +RE GP DP +AR P ++RA +G NAVH +
Sbjct: 458 YVT---SGPVVAFEIVGENAVGAWREAIGPTDPSLARKEAPTSIRAQYGTDVTCNAVHGS 628
Query: 358 DLPEDGLLEVQYFF 371
D P EV++FF
Sbjct: 629 DSPGSAAREVEFFF 670
Score = 66.2 bits (160), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 45/142 (31%), Positives = 70/142 (49%), Gaps = 13/142 (9%)
Frame = +1
Query: 94 TLALIKPDAISK--AGEIIEIINKAGFTITKLKMMMLSRKEALDF-----HVDHQSRPFF 146
T +IKP A AG+II I +AGF + +M L + A +F V H+ +
Sbjct: 718 TCCIIKPSAFKAGVAGKIINAITEAGFRVGSAEMFTLEKANAEEFLEVYKGVVHE----Y 885
Query: 147 NELIQFITTGPIIAMEILRDDAI------CEWKRLLGPANSGVARTDASESIRALFGTDG 200
++ +T+GP +A+EI+ ++ L GP + +AR ++RA+FGTD
Sbjct: 886 PAMVTELTSGPCLALEIVGGSGTNASLLAPAFRELAGPVDPEIARHLRPRTLRAMFGTDK 1065
Query: 201 IRNAAHGPDSFASAAREMELFF 222
I+NA H D E+E FF
Sbjct: 1066IKNAVHCTDLPDDGPLEVEYFF 1131
>02656
Length = 2642
Score = 170 bits (430), Expect = 9e-43, Method: Compositional matrix adjust.
Identities = 98/286 (34%), Positives = 153/286 (53%), Gaps = 2/286 (0%)
Frame = +3
Query: 92 EKTLALIKPDAISKAGE-IIEIINKAGFTITKLKMMMLSRKEALDFHVDHQSRPFFNELI 150
++TLALI+PDA + + I+E I +AGF I K + L++++A +F+ +H +P+++EL
Sbjct: 669 QRTLALIRPDAFANNKDAILEKIKEAGFQIALHKEVSLTKEQAEEFYKEHAGQPYYDELT 848
Query: 151 QFITTGPIIAMEILRDDAICEWKRLLGPANSGVARTDASESIRALFGTDGIR-NAAHGPD 209
+++GP++A+ + R+DA+ W+ +LGP + A+T A + +RA F D N HG D
Sbjct: 849 DRMSSGPLLALGLAREDAVENWREMLGPTDVEEAKTAAPDCLRAQFAVDSTAINQLHGSD 1028
Query: 210 SFASAAREMELFFPSSGGCGPANTAKFTNCTCCIVKPHAVSEGLLGKILMAIRDAGFEIS 269
S SA +E+E FFP T ++KP G I+ I AGF I+
Sbjct: 1029STQSAKKELEFFFP-------------VEQTVAMIKPDGY--GTKDAIIEKIHQAGFRIA 1163
Query: 270 AMQMFNMDRVNVEEFYEVYKGVVTEYHDMVTEMYSGPCVAMEIQQNNATKTFREFCGPAD 329
A + + R E FY+ K Y +V M SGP + M + + A +RE GP D
Sbjct: 1164ARKETTITRDIAESFYDDQKD-KDYYESLVEHMTSGPTMFMVLSREGAVDGWREEIGPTD 1340
Query: 330 PEIARHLRPGTLRAIFGKTKIQNAVHCTDLPEDGLLEVQYFFKILD 375
P A+ P +LRA FG +QNAVH E+ +++ F LD
Sbjct: 1341PTKAKEQNPNSLRAQFGTDVLQNAVHGASSSEEAKKKIKAVFGDLD 1478
Score = 151 bits (382), Expect = 4e-37, Method: Compositional matrix adjust.
Identities = 92/289 (31%), Positives = 154/289 (53%), Gaps = 9/289 (3%)
Frame = +3
Query: 94 TLALIKPDAIS--KAGEIIEIINKAGFTITKLKMMMLSRKEALDFHVDHQSRPFFNELIQ 151
T+A+IKP+ ++ K EI+ + G + + L+ EA +F+ Q +F +L+
Sbjct: 219 TVAIIKPNVVANGKVDEILAEMKARGINVKAQEERQLTEDEAREFYSHLQGEEYFEDLVA 398
Query: 152 FITTGP---IIAMEILRDDAIC-EWKRLLGPANSGVARTDASESIRALFGTDGIRNAAHG 207
F+ +GP ++ E DD++ +W+ +LGP A+ A ES+RA +G G+ NA HG
Sbjct: 399 FMASGPSHVLVLTEGQEDDSVVKDWRDMLGPPTVEDAKEQAPESLRARYGQGGLMNAVHG 578
Query: 208 PDSFASAAREMELFFPSSGGCGPANTAKFTNCTCCIVKPHAVSEGLLGKILMAIRDAGFE 267
DS +AARE+ FFP K T +++P A + IL I++AGF+
Sbjct: 579 SDSKETAARELAFFFPHMQAPKLQKKKKEVQRTLALIRPDAFANNKDA-ILEKIKEAGFQ 755
Query: 268 ISAMQMFNMDRVNVEEFYEVYKGVVTEYHDMVTE-MYSGPCVAMEIQQNNATKTFREFCG 326
I+ + ++ + EEFY+ + G Y+D +T+ M SGP +A+ + + +A + +RE G
Sbjct: 756 IALHKEVSLTKEQAEEFYKEHAG--QPYYDELTDRMSSGPLLALGLAREDAVENWREMLG 929
Query: 327 PADPEIARHLRPGTLRAIFG--KTKIQNAVHCTDLPEDGLLEVQYFFKI 373
P D E A+ P LRA F T I N +H +D + E+++FF +
Sbjct: 930 PTDVEEAKTAAPDCLRAQFAVDSTAI-NQLHGSDSTQSAKKELEFFFPV 1073
>02733
Length = 853
Score = 76.3 bits (186), Expect(2) = 4e-15, Method: Compositional matrix adjust.
Identities = 35/110 (31%), Positives = 63/110 (57%)
Frame = -1
Query: 113 INKAGFTITKLKMMMLSRKEALDFHVDHQSRPFFNELIQFITTGPIIAMEILRDDAICEW 172
I++AGF I K ++R A F+ D + + ++ L++ +T+GP + M + R+ A+ W
Sbjct: 742 IHQAGFRIAARKETTITRDIAESFYDDQKDKDYYESLVEHMTSGPTMFMVLSREGAVDGW 563
Query: 173 KRLLGPANSGVARTDASESIRALFGTDGIRNAAHGPDSFASAAREMELFF 222
+ +GP + A+ S+RA FGTD ++NA HG S A ++++ F
Sbjct: 562 REEIGPTDPTKAKEQNPNSLRAQFGTDVLQNAVHGASSSEEAKKKIKAVF 413
Score = 22.3 bits (46), Expect(2) = 4e-15, Method: Compositional matrix adjust.
Identities = 9/19 (47%), Positives = 14/19 (73%)
Frame = -2
Query: 92 EKTLALIKPDAISKAGEII 110
++TLALI+PDA + + I
Sbjct: 807 QRTLALIRPDAFANNKDAI 751
Score = 68.6 bits (166), Expect = 4e-12, Method: Compositional matrix adjust.
Identities = 41/115 (35%), Positives = 57/115 (49%)
Frame = -1
Query: 261 IRDAGFEISAMQMFNMDRVNVEEFYEVYKGVVTEYHDMVTEMYSGPCVAMEIQQNNATKT 320
I AGF I+A + + R E FY+ K Y +V M SGP + M + + A
Sbjct: 742 IHQAGFRIAARKETTITRDIAESFYDDQKDK-DYYESLVEHMTSGPTMFMVLSREGAVDG 566
Query: 321 FREFCGPADPEIARHLRPGTLRAIFGKTKIQNAVHCTDLPEDGLLEVQYFFKILD 375
+RE GP DP A+ P +LRA FG +QNAVH E+ +++ F LD
Sbjct: 565 WREEIGPTDPTKAKEQNPNSLRAQFGTDVLQNAVHGASSSEEAKKKIKAVFGDLD 401
>14087
Length = 2025
Score = 34.7 bits (78), Expect(2) = 5e-06, Method: Compositional matrix adjust.
Identities = 16/43 (37%), Positives = 23/43 (53%)
Frame = +3
Query: 333 ARHLRPGTLRAIFGKTKIQNAVHCTDLPEDGLLEVQYFFKILD 375
A+ P +LRA FG +QNAVH E+ +++ F LD
Sbjct: 120 AKEQNPNSLRAQFGTDVLQNAVHGASSSEEAKKKIKAVFGDLD 248
Score = 33.1 bits (74), Expect(2) = 5e-06, Method: Compositional matrix adjust.
Identities = 14/36 (38%), Positives = 19/36 (52%)
Frame = +2
Query: 295 YHDMVTEMYSGPCVAMEIQQNNATKTFREFCGPADP 330
Y +V M SGP + M + + A +RE GP DP
Sbjct: 5 YESLVEHMTSGPTMFMVLSREGAVDGWREEIGPTDP 112
Score = 33.9 bits (76), Expect(2) = 1e-05, Method: Compositional matrix adjust.
Identities = 15/50 (30%), Positives = 29/50 (58%)
Frame = +2
Query: 145 FFNELIQFITTGPIIAMEILRDDAICEWKRLLGPANSGVARTDASESIRA 194
++ L++ +T+GP + M + R+ A+ W+ +GP TD ++S RA
Sbjct: 2 YYESLVEHMTSGPTMFMVLSREGAVDGWREEIGP-------TDPTKSQRA 130
Score = 32.0 bits (71), Expect(2) = 1e-05, Method: Compositional matrix adjust.
Identities = 14/32 (43%), Positives = 21/32 (65%)
Frame = +3
Query: 191 SIRALFGTDGIRNAAHGPDSFASAAREMELFF 222
S+RA FGTD ++NA HG S A ++++ F
Sbjct: 141 SLRAQFGTDVLQNAVHGASSSEEAKKKIKAVF 236
>31902
Length = 546
Score = 45.1 bits (105), Expect = 5e-05, Method: Compositional matrix adjust.
Identities = 21/52 (40%), Positives = 29/52 (55%)
Frame = +1
Query: 172 WKRLLGPANSGVARTDASESIRALFGTDGIRNAAHGPDSFASAAREMELFFP 223
W+ +GP + +AR +A SIRA +GTD NA HG DS + + L P
Sbjct: 388 WREAIGPTDPSLARKEAPTSIRAQYGTDVTCNAVHGSDSPGNWPVPLTLRLP 543
Score = 43.1 bits (100), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 25/88 (28%), Positives = 45/88 (51%), Gaps = 1/88 (1%)
Frame = +1
Query: 274 FNMDRVNVEEFYE-VYKGVVTEYHDMVTEMYSGPCVAMEIQQNNATKTFREFCGPADPEI 332
F+++ ++ + + KG + ++ +T ++ PC A + +RE GP DP +
Sbjct: 250 FSLELIHTHKLPTWMMKGTASSWNGTMTCQHA-PC-ASSSSTSPTPSLWREAIGPTDPSL 423
Query: 333 ARHLRPGTLRAIFGKTKIQNAVHCTDLP 360
AR P ++RA +G NAVH +D P
Sbjct: 424 ARKEAPTSIRAQYGTDVTCNAVHGSDSP 507
Score = 33.1 bits (74), Expect = 0.21, Method: Compositional matrix adjust.
Identities = 12/32 (37%), Positives = 19/32 (59%)
Frame = +3
Query: 5 ERFVFIAEWYDPNASLLRRYELLFYPGDGSVE 36
ER+ FI EWYD ++ R++ ++ SVE
Sbjct: 297 ERYSFIVEWYDDMSARTLRFQFFYFTNSKSVE 392
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000366568 | hsapiens_gene_ensembl |
Ubiquitin-activating enzyme E1 (A1S9 protein).
[Source:Uniprot/SWISSPROT;Acc:P22314]
(1058 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
34235 226 e-100
19711 170 8e-86
21876 290 2e-78
25566 257 2e-68
00369 118 1e-26
21008 117 3e-26
06604 117 3e-26
20367 75 1e-13
14935 40 0.007
>34235
Length = 1026
Score = 226 bits (575), Expect(3) = e-100, Method: Compositional matrix adjust.
Identities = 110/194 (56%), Positives = 133/194 (68%), Gaps = 1/194 (0%)
Frame = -1
Query: 741 FWSGPKRCPHPLTFDVNNPLHLDYVMAAANLFAQTYGLTGSQDRAAVATFLQSVQVPEFT 800
FWSGPKRCPH L FD +N LHLDY+ AAAN+ GL +DRAA+ + V VPEF
Sbjct: 876 FWSGPKRCPHALEFDADNELHLDYIEAAANMKGFMCGLPPVRDRAAIKDMVSKVMVPEFV 697
Query: 801 PKSGVKIHVSDQELQSANA-SVDDSRLEELKATLPSPDKLPGFKMYPIDFEKDDDSNFHM 859
P+SG+KI V+D E Q+ N + D +E+LK+ LPSPD+L G ++ +DFEKDDD+NFHM
Sbjct: 696 PRSGIKIAVTDAEAQAGNNDNFDKDTVEKLKSALPSPDELKGRQLNAVDFEKDDDTNFHM 517
Query: 860 DFIVAASNLRAENYDIPSADRHKSKLXXXXXXXXXXXXXXXVVGLVCLELYKVVQGHRQL 919
DFI AASNLRAENY IP ADRHKSKL VVGLV LEL K+ QGH +
Sbjct: 516 DFITAASNLRAENYSIPPADRHKSKLIAGRIIPAIATTTAMVVGLVGLELIKLAQGHTNV 337
Query: 920 DSYKNGFLNLALPF 933
+ +KNGF NLALP
Sbjct: 336 ERFKNGFANLALPL 295
Score = 125 bits (313), Expect(3) = e-100, Method: Compositional matrix adjust.
Identities = 63/107 (58%), Positives = 81/107 (75%)
Frame = -2
Query: 931 LPFFGFSEPLAAPRHQYYNQEWTLWDRFEVQGLQPNGEEMTLKQFLDYFKTEHKLEITML 990
L F FSEP+ AP+ +YY +E+TLWDRF VQG E+TL+QFLDYF+ EH LEITML
Sbjct: 305 LSLFAFSEPILAPKSKYYEKEFTLWDRFTVQG------EITLQQFLDYFQKEHGLEITML 144
Query: 991 SQGVSMLYSFFMPAAKLKERLDQPMTEIVSRVSKRKLGRHVRALVLE 1037
SQGV +L+S FM AK +ER + ++E+V +VSK+K+ HVRALVLE
Sbjct: 143 SQGVCLLFSNFMQPAKQEERKNLLISELVKKVSKKKIPPHVRALVLE 3
Score = 57.0 bits (136), Expect(3) = e-100, Method: Compositional matrix adjust.
Identities = 25/41 (60%), Positives = 30/41 (73%)
Frame = -3
Query: 706 CVTWACHHWHTQYSNNIRQLLHNFPPDQLTSSGAPFWSGPK 746
CV WA + + T YSN I+QLL NFP DQ+TSSGAPF G +
Sbjct: 982 CVEWARNLFQTNYSNQIKQLLFNFPSDQMTSSGAPFLVGSQ 860
>19711
Length = 1114
Score = 170 bits (430), Expect(2) = 8e-86, Method: Compositional matrix adjust.
Identities = 84/171 (49%), Positives = 109/171 (63%), Gaps = 2/171 (1%)
Frame = +3
Query: 200 CDFGEEMILTDSNGEQPLSAMVSMVTKDNPGVVTCLDEARHGFESGDFVSFSEVQGMVEL 259
CDFG+ + D GE+ ++ +TK NPGVVTCLD HG E+GD V+F EV+GM +L
Sbjct: 3 CDFGDTFEVMDPTGEEAKEVFIANITKANPGVVTCLDNLLHGLETGDLVTFKEVKGMEQL 182
Query: 260 NGNQPMEIKVLGPYTFSICDTSN--FSDYIRGGIVSQVKVPKKISFKSLVASLAEPDFVV 317
N Q IKVL P TFSIC+TS F Y GGI+SQVKVPK + FKSL L P ++
Sbjct: 183 NSQQ-CAIKVLSPTTFSICNTSGSEFGAYESGGIISQVKVPKSVHFKSLEEQLVSPSLLM 359
Query: 318 TDFAKFSRPAQLHIGFQALHQFCAQHGRPPRPRNEEDAAELVALAQAVNAR 368
D KF+ P +H+ FQALHQF A+ G P+P + A +V LA+A +A+
Sbjct: 360 PDLCKFTAPGNIHVAFQALHQFWAETGSLPQPWCSDSADRMVLLAKACSAK 512
Score = 166 bits (421), Expect(2) = 8e-86, Method: Compositional matrix adjust.
Identities = 85/196 (43%), Positives = 120/196 (61%), Gaps = 1/196 (0%)
Frame = +2
Query: 372 AVQQNNLDEDLIRKLAYVAAGDLAPINAFIGGLAAQEVMKACSGKFMPIMQWLYFDALEC 431
+ ++E ++R L++ A G LAP+ A +GG+ AQE +KA +GKF+P+ QWLY DA+E
Sbjct: 527 GTEAEEVEEKIVRCLSHTARGSLAPLCAAMGGIVAQEGLKALTGKFLPLSQWLYLDAMET 706
Query: 432 LPEDKEVLTEDKCLQRQNRYDGQVAVFGSDLQEKLGKQKYFLVGAGAIGCELLKNFAMXX 491
+PE V + + R +R D G D+ +KL + F+VG GAIGCE+LKN+A+
Sbjct: 707 IPE-LSVTSPEAFQLRNDRLDPLRICVGEDVCQKLADTRLFMVGCGAIGCEMLKNYALLG 883
Query: 492 XXXXXXXXXXVTDMDTIEKSNLNRQFLFRPWDVTKLKSDTAAAAVRQMNPHIRVTSHQNR 551
+TD D IEKSNLNRQFLFR + K KS TAA +V +NP + + + QN+
Sbjct: 884 LGAGQKGQITITDNDLIEKSNLNRQFLFRSHHIQKPKSTTAAQSVLDINPALHIQAQQNK 1063
Query: 552 VGPDTERI-YDDDFFQ 566
V P TE Y D FF+
Sbjct: 1064VCPQTESTHYPDAFFE 1111
>21876
Length = 894
Score = 290 bits (743), Expect = 2e-78, Method: Compositional matrix adjust.
Identities = 153/305 (50%), Positives = 204/305 (66%), Gaps = 9/305 (2%)
Frame = -1
Query: 44 NGSEADIDEGLYSRQLYVLGHEAMKR---LQTSSVLVSGLRGLGVEIAKNIILGGVKAVT 100
NG+ DIDEGL GHEAM++ LQ S + G GLG+EIAKN++LGGVK+V+
Sbjct: 894 NGAADDIDEGLVXSPAVCAGHEAMRKMAKLQCSDLWAMG--GLGIEIAKNVVLGGVKSVS 721
Query: 101 LHDQGTAQWADLSSQFYLREEDIGKNRAEVSQPRLAELNSYVPVTAYTGPLVEDFLSGFQ 160
+HD G + DLSSQF+LR+ED+GKNRAEVSQPRLAELNSYVP+++ TG DF G
Sbjct: 720 IHDPGKVVFGDLSSQFFLRDEDVGKNRAEVSQPRLAELNSYVPISSSTG----DFG*GLL 553
Query: 161 VVVLTNTPLEDQLRV------GEFCHNRGIKLVVADTRGLFGQLFCDFGEEMILTDSNGE 214
V V + DQL V G ++ + DFG ++TD +GE
Sbjct: 552 VQVSGGS--TDQLFVR*TDPCGRVLSLSQHQVHCGRNAWTVWENLLDFGSNFVITDGDGE 379
Query: 215 QPLSAMVSMVTKDNPGVVTCLDEARHGFESGDFVSFSEVQGMVELNGNQPMEIKVLGPYT 274
QP+S M++ + K + VV +DE +HG E GD+V+F EVQGM ELNG +P++IKVLGPYT
Sbjct: 378 QPISCMIADIEKGDNSVVATVDETKHGLEDGDYVTFKEVQGMTELNGCKPVKIKVLGPYT 199
Query: 275 FSICDTSNFSDYIRGGIVSQVKVPKKISFKSLVASLAEPDFVVTDFAKFSRPAQLHIGFQ 334
FSI DT+ ++DYIRGG +QVK+PK I+FKS+ A++ P+ + +DFAKF RP QLHI F+
Sbjct: 198 FSIGDTTKYADYIRGGTATQVKMPKTINFKSIKAAMDAPEILPSDFAKFDRPPQLHIAFK 19
Query: 335 ALHQF 339
AL ++
Sbjct: 18 ALSEY 4
>25566
Length = 1639
Score = 257 bits (657), Expect = 2e-68, Method: Compositional matrix adjust.
Identities = 171/467 (36%), Positives = 247/467 (52%), Gaps = 11/467 (2%)
Frame = +2
Query: 600 TLGTKGNVQVVIPFLTESYSSSQDPPEKSIPICTLKNFPNAIEHTLQWARDEFEGLFKQP 659
T+GTKG+VQV+IP LTESY+S QDP ++ P CT+K+FP IEH +QWARD+FE L+
Sbjct: 2 TMGTKGHVQVIIPHLTESYTSQQDPADEDYPYCTVKSFPATIEHCIQWARDKFEELYVNQ 181
Query: 660 AENVNQYLTDPKFVERTLRLAGTQPLEVLEAVQR--SLVLQRPQTWADCVTWACHHWHTQ 717
N++L + T + + +V++ R + RP +W DCV A +
Sbjct: 182 PNLFNKFLASN--ADMTAVVHKLKSGDVVDGGLRVSKMAATRPHSWEDCVRLARIRFEKY 355
Query: 718 YSNNIRQLLHNFPPDQLTSSGAPFWSGPKRCPHPLTFDVNNPLHLDYVMAAANLFAQTYG 777
+++ RQLLH FP D + FW PKR P PL F+ ++PLH+ +V + A L Y
Sbjct: 356 FNHKARQLLHAFPLDIKLPDNSLFWQSPKRPPTPLQFNADDPLHMTFVTSTARLLCDIYA 535
Query: 778 LTGSQDRA--AVATFLQSVQVPEFTPKSGVKIHVSDQ------ELQSANASVDDSRLEEL 829
++ S + ++ T L +V VP F P S KI + E QS+ V +
Sbjct: 536 ISYSTQVSTDSIKTILHAVTVPAFVP-SDKKIETDETKSQQEAEPQSSGDEVTAAGERLA 712
Query: 830 KATLPSPDKLPGFKMYPIDFEKDDDSNFHMDFIVAASNLRAENYDIPSADRHKSKLXXXX 889
+ + S + M ++FEKDDDSN H++FI A SN+RA+ Y I + DR K K
Sbjct: 713 QVVMSSQAQSALQPMAALEFEKDDDSNDHINFIAACSNMRAQMYSIENVDRLKIKRIAGR 892
Query: 890 XXXXXXXXXXXVVGLVCLELYKVVQGHRQLDSYKNGFLNLALPFFGFSEPLAAPRHQYYN 949
V GLV +EL KV+Q R LD++KN FLNLALP SEP A R
Sbjct: 893 IVPAIATTTAAVSGLVTIELIKVLQ-QRPLDAFKNAFLNLALPMLLLSEPGACARKVLKE 1069
Query: 950 Q-EWTLWDRFEVQGLQPNGEEMTLKQFLDYFKTEHKLEITMLSQGVSMLYSFFMPAAKLK 1008
++WD++ ++G Q + TL+QFLD K E T + GV ++Y MP K
Sbjct: 1070 GLSVSVWDKWTIRGKQ----DFTLQQFLDSCKDSFGFEATAVVNGVKIIYMPIMPPH--K 1231
Query: 1009 ERLDQPMTEIVSRVSKRKLGRHVRALVLELCCNDESGEDVEVPYVRY 1055
+RL Q M +++ K + + L +C D+ GE++E P VRY
Sbjct: 1232 KRLPQTMMKLI------KPEPGITYVDLVVCFEDDKGEEIEGPPVRY 1354
>00369
Length = 1082
Score = 118 bits (296), Expect = 1e-26, Method: Compositional matrix adjust.
Identities = 70/207 (33%), Positives = 108/207 (52%), Gaps = 14/207 (6%)
Frame = +3
Query: 470 KYFLVGAGAIGCELLKNFAMXXXXXXXXXXXXVTDMDTIEKSNLNRQFLFRPWDVTKLKS 529
K ++GAG +GCELLK+ A+ V DMDTI+ SNLNRQFLFRP DV K+
Sbjct: 222 KLLVIGAGGLGCELLKDLALMGFFDIH-----VIDMDTIDVSNLNRQFLFRPKDVGSPKA 386
Query: 530 DTAAAAVRQMNPHIRVTSHQNRVGPDTERIYDDDFFQNLDGVANALDNVDARMYMDRRCV 589
+ AAA + P +VT H ++ + YD+ F++ + LD++ AR +++ +
Sbjct: 387 EVAAAFINSRVPGCKVTPHFAKI-----QDYDESFYRGFHVIVCGLDSIIARRWINSMLI 551
Query: 590 YYRK------------PLLESGTLGTKGNVQVVIPFLTESYSSSQD--PPEKSIPICTLK 635
PL++ GT G KGN +VV+P +T + D PP+ + P+CT+
Sbjct: 552 SLLNYEDGELDQSSIIPLVDGGTEGFKGNARVVLPGITACIECTLDLYPPQVNFPLCTIA 731
Query: 636 NFPNAIEHTLQWARDEFEGLFKQPAEN 662
+ P EH +++ R + P EN
Sbjct: 732 HTPRLPEHCIEYVR-----ILLWPKEN 797
Score = 51.2 bits (121), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 34/99 (34%), Positives = 50/99 (50%), Gaps = 6/99 (6%)
Frame = +3
Query: 71 QTSSVLVSGLRGLGVEIAKNIILGGVKAVTLHDQGTAQWADLSSQFYLREEDIGKNRAEV 130
+T +LV G GLG E+ K++ L G + + D T ++L+ QF R +D+G +AEV
Sbjct: 213 ETCKLLVIGAGGLGCELLKDLALMGFFDIHVIDMDTIDVSNLNRQFLFRPKDVGSPKAEV 392
Query: 131 SQPRLAELNSYVPVTAYTGPLV------EDFLSGFQVVV 163
+ A +NS VP T E F GF V+V
Sbjct: 393 AA---AFINSRVPGCKVTPHFAKIQDYDESFYRGFHVIV 500
>21008
Length = 408
Score = 117 bits (293), Expect = 3e-26, Method: Compositional matrix adjust.
Identities = 63/128 (49%), Positives = 84/128 (65%), Gaps = 2/128 (1%)
Frame = +3
Query: 19 PGSNCSPAQSVLSEVPSVPTNGMAKNGSEADIDEGLYSRQLYVLGHEAMKRLQTSSVLVS 78
PG NC ++ T MA S+ +ID+ LYSRQ YVLG AMKR+ SSVL+
Sbjct: 54 PGFNCF-------KINLCNTETMA---SDMEIDDSLYSRQRYVLGDSAMKRMAQSSVLIH 203
Query: 79 GLRGLGVEIAKNIILGGVKAVTLHDQGTAQWADLSSQFYLREEDI--GKNRAEVSQPRLA 136
GL GLG+EIAKNI+L GVK++T+ D T+ +DL +QF++R+ D+ KNRAE +LA
Sbjct: 204 GLGGLGIEIAKNIVLAGVKSLTVQDSKTSCTSDLGTQFFVRQADVDAAKNRAEACAGKLA 383
Query: 137 ELNSYVPV 144
ELN YV +
Sbjct: 384 ELNPYVKI 407
>06604
Length = 1748
Score = 117 bits (292), Expect = 3e-26, Method: Compositional matrix adjust.
Identities = 62/153 (40%), Positives = 89/153 (58%), Gaps = 3/153 (1%)
Frame = -2
Query: 54 LYSRQLYVLGHEAMKRLQTSSVLVSGLRGLGVEIAKNIILGGVKAVTLHDQGTAQWADLS 113
LY RQ+ + G +A +RL+ +SVL+ G+RGLG E+AKNI+L G+K++TL D A D +
Sbjct: 1732 LYDRQIRLWGLDAQRRLRAASVLLVGVRGLGAEVAKNIVLAGIKSLTLLDPSLADEEDTA 1553
Query: 114 SQFYLREEDIGKNRAEVSQPRLAELNSYVPVTAYTGPL---VEDFLSGFQVVVLTNTPLE 170
+QF + +IGKNRAE S R LN V VTA T + +DF++ F VV T +
Sbjct: 1552 AQFLIPRSEIGKNRAEASLERTQLLNPMVTVTADTCSIDDKDDDFVTSFDVVCATGCGVS 1373
Query: 171 DQLRVGEFCHNRGIKLVVADTRGLFGQLFCDFG 203
R+ C + G+ D G +G +F D G
Sbjct: 1372 TLRRLDRVCRDAGVMFYAGDVFGFYGYMFADLG 1274
Score = 43.5 bits (101), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 33/138 (23%), Positives = 56/138 (40%)
Frame = -2
Query: 451 YDGQVAVFGSDLQEKLGKQKYFLVGAGAIGCELLKNFAMXXXXXXXXXXXXVTDMDTIEK 510
YD Q+ ++G D Q +L LVG +G E+ KN + + D +
Sbjct: 1729 YDRQIRLWGLDAQRRLRAASVLLVGVRGLGAEVAKNIVLAGIKSLTLLDPSLAD-----E 1565
Query: 511 SNLNRQFLFRPWDVTKLKSDTAAAAVRQMNPHIRVTSHQNRVGPDTERIYDDDFFQNLDG 570
+ QFL ++ K +++ + + +NP + VT+ + DDDF + D
Sbjct: 1564 EDTAAQFLIPRSEIGKNRAEASLERTQLLNPMVTVTADTCSIDDK-----DDDFVTSFDV 1400
Query: 571 VANALDNVDARMYMDRRC 588
V V +DR C
Sbjct: 1399 VCATGCGVSTLRRLDRVC 1346
Score = 38.1 bits (87), Expect = 0.020, Method: Compositional matrix adjust.
Identities = 27/99 (27%), Positives = 48/99 (48%), Gaps = 2/99 (2%)
Frame = -3
Query: 334 QALHQFCAQHGRPPRPRNEE-DAAELVAL-AQAVNARALPAVQQNNLDEDLIRKLAYVAA 391
+AL +F Q R P ++E D +L L Q + + N + ED +
Sbjct: 1044 KALLEFLEQQKRRPATSSQESDCQQLSKLRXQXLZSXG---AGDNKMAEDFTQ----YCF 886
Query: 392 GDLAPINAFIGGLAAQEVMKACSGKFMPIMQWLYFDALE 430
G L+P+ A +GG+ QE++KA S K +P + +++ +
Sbjct: 885 GQLSPVCAVVGGILGQEIIKAVSQKDIPHNNFFFYNGTD 769
>20367
Length = 859
Score = 75.5 bits (184), Expect = 1e-13, Method: Composition-based stats.
Identities = 52/165 (31%), Positives = 76/165 (46%), Gaps = 11/165 (6%)
Frame = -1
Query: 55 YSRQLYVLGHEAMKRLQTSSVLVSGLRGLGVEIAKNIILGGVKAVTLHDQGTAQWADLSS 114
Y RQL + G L+T+ V + G EI KN+IL G+ + T+ D Q D+ +
Sbjct: 814 YDRQLRLWGDHGQSALETARVCLINATATGTEILKNVILPGIGSFTIVDGNKVQGEDVGN 635
Query: 115 QFYLREEDIGKNRAEVSQPRLAELNSYVPVTAYTGPLVE-----------DFLSGFQVVV 163
F+L+ + IGK+RA+V+ L ELN V TG VE DF + F +V+
Sbjct: 634 NFFLQVDSIGKSRAQVATELLGELNDDV-----TGNFVEENVENLLESNADFFTTFSIVI 470
Query: 164 LTNTPLEDQLRVGEFCHNRGIKLVVADTRGLFGQLFCDFGEEMIL 208
TN + L++ I L+V G G L E I+
Sbjct: 469 ATNLHEKTLLQLAGVLWENNIPLLVCRCYGFIGYLRLVLKEHTII 335
Score = 36.2 bits (82), Expect = 0.078, Method: Composition-based stats.
Identities = 29/131 (22%), Positives = 57/131 (43%), Gaps = 3/131 (2%)
Frame = -1
Query: 438 VLTEDKC-LQRQNRYDGQVAVFGSDLQEKLGKQKYFLVGAGAIGCELLKNFAMXXXXXXX 496
++ E K L + N+YD Q+ ++G Q L + L+ A A G E+LKN +
Sbjct: 856 IMAETKTGLDKNNKYDRQLRLWGDHGQSALETARVCLINATATGTEILKNVIL-----PG 692
Query: 497 XXXXXVTDMDTIEKSNLNRQFLFRPWDVTKLKSDTAAAAVRQMNPHIRVTSHQNRVGPDT 556
+ D + ++ ++ F + + K ++ A + ++N + N V +
Sbjct: 691 IGSFTIVDGNKVQGEDVGNNFFLQVDSIGKSRAQVATELLGELNDDVT----GNFVEENV 524
Query: 557 ERIYDD--DFF 565
E + + DFF
Sbjct: 523 ENLLESNADFF 491
>14935
Length = 378
Score = 39.7 bits (91), Expect = 0.007, Method: Compositional matrix adjust.
Identities = 21/62 (33%), Positives = 32/62 (51%), Gaps = 2/62 (3%)
Frame = -2
Query: 614 LTESYSSSQDPPEKSIPICTLKNFPNAIEHTLQWARDEFEGLF--KQPAENVNQYLTDPK 671
LTE Y +KS P CT++N P+ H + WA+ F LF + P ++V+ DP+
Sbjct: 377 LTECYECQPKAAQKSFPGCTIRNTPSEPIHCVVWAKHLFNQLFGEEDPDQDVSPDTEDPE 198
Query: 672 FV 673
Sbjct: 197 LT 192
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000375953 | hsapiens_gene_ensembl | Nucleoside
diphosphate kinase 7 (EC 2.7.4.6) (NDK 7) (NDP kinase 7) (nm23-H7).
[Source:Uniprot/SWISSPROT;Acc:Q9Y5B8]
(376 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
32935 190 1e-98
02656 168 3e-42
02733 76 4e-15
14087 34 1e-05
31902 45 5e-05
>32935
Length = 1188
Score = 190 bits (483), Expect(2) = 1e-98, Method: Compositional matrix adjust.
Identities = 90/150 (60%), Positives = 107/150 (71%), Gaps = 6/150 (4%)
Frame = +1
Query: 232 NTAKFTNCTCCIVKPHAVSEGLLGKILMAIRDAGFEISAMQMFNMDRVNVEEFYEVYKGV 291
NTA NCTCCI+KP A G+ GKI+ AI +AGF + + +MF +++ N EEF EVYKGV
Sbjct: 694 NTASIGNCTCCIIKPSAFKAGVAGKIINAITEAGFRVGSAEMFTLEKANAEEFLEVYKGV 873
Query: 292 VTEYHDMVTEMYSGPCVAMEIQQNNATK------TFREFCGPADPEIARHLRPGTLRAIF 345
V EY MVTE+ SGPC+A+EI + T FRE GP DPEIARHLRP TLRA+F
Sbjct: 874 VHEYPAMVTELTSGPCLALEIVGGSGTNASLLAPAFRELAGPVDPEIARHLRPRTLRAMF 1053
Query: 346 GKTKIQNAVHCTDLPEDGLLEVRYFFLICD 375
G KI+NAVHCTDLP+DG LEV YFF I D
Sbjct: 1054GTDKIKNAVHCTDLPDDGPLEVEYFFKILD 1143
Score = 188 bits (477), Expect(2) = 1e-98, Method: Compositional matrix adjust.
Identities = 93/232 (40%), Positives = 144/232 (62%), Gaps = 6/232 (2%)
Frame = +2
Query: 5 ERFVFIAEWYDPNASLLRRYELLFYPGD---GSV---EMHDVKNHRTFLKRTKYDNLHLE 58
ER+ FI EWYD ++ R++ ++ G V E DV +++ +R + L
Sbjct: 11 ERYSFIVEWYDDMSARTLRFQFFYFTNSQVCGDVRHKEPQDVSANQSERQRAQ----SLR 178
Query: 59 DLFIGNKVNVFSRQLVLIDYGDQYTARQLGSRKEKTLALIKPDAISKAGEIIEIINKAGF 118
+ R L ++DY D+YT R+L S++E+TL LIKPDA+ K G++++ I + GF
Sbjct: 179 PVHWQQHQPPAPRLLTIVDYDDEYTRRKLTSKRERTLGLIKPDAVEKLGQVLDKILQKGF 358
Query: 119 TITKLKMMMLSRKEALDFHVDHQSRPFFNELIQFITTGPIIAMEILRDDAICEWKRLLGP 178
I++L+M L R AL+F+ +H+S+PF N L+ ++T+GP++A EI+ ++A+ W+ +GP
Sbjct: 359 LISRLRMCKLDRNTALEFYQEHRSKPFLNALLDYVTSGPVVAFEIVGENAVGAWREAIGP 538
Query: 179 ANSGVARTDASESIRALFGTDGIRNAAHGPDSFASAAREMELFFPSSGGCGP 230
+ +AR +A SIRA +GTD NA HG DS SAARE+E FFPSSG P
Sbjct: 539 TDPSLARKEAPTSIRAQYGTDVTCNAVHGSDSPGSAAREVEFFFPSSGSHSP 694
Score = 87.8 bits (216), Expect = 6e-18, Method: Compositional matrix adjust.
Identities = 54/134 (40%), Positives = 72/134 (53%), Gaps = 2/134 (1%)
Frame = +2
Query: 240 TCCIVKPHAVSEGLLGKILMAIRDAGFEISAMQMFNMDRVNVEEFYEVY--KGVVTEYHD 297
T ++KP AV + LG++L I GF IS ++M +DR EFY+ + K + D
Sbjct: 284 TLGLIKPDAVEK--LGQVLDKILQKGFLISRLRMCKLDRNTALEFYQEHRSKPFLNALLD 457
Query: 298 MVTEMYSGPCVAMEIQQNNATKTFREFCGPADPEIARHLRPGTLRAIFGKTKIQNAVHCT 357
VT SGP VA EI NA +RE GP DP +AR P ++RA +G NAVH +
Sbjct: 458 YVT---SGPVVAFEIVGENAVGAWREAIGPTDPSLARKEAPTSIRAQYGTDVTCNAVHGS 628
Query: 358 DLPEDGLLEVRYFF 371
D P EV +FF
Sbjct: 629 DSPGSAAREVEFFF 670
Score = 66.2 bits (160), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 45/142 (31%), Positives = 70/142 (49%), Gaps = 13/142 (9%)
Frame = +1
Query: 94 TLALIKPDAISK--AGEIIEIINKAGFTITKLKMMMLSRKEALDF-----HVDHQSRPFF 146
T +IKP A AG+II I +AGF + +M L + A +F V H+ +
Sbjct: 718 TCCIIKPSAFKAGVAGKIINAITEAGFRVGSAEMFTLEKANAEEFLEVYKGVVHE----Y 885
Query: 147 NELIQFITTGPIIAMEILRDDAI------CEWKRLLGPANSGVARTDASESIRALFGTDG 200
++ +T+GP +A+EI+ ++ L GP + +AR ++RA+FGTD
Sbjct: 886 PAMVTELTSGPCLALEIVGGSGTNASLLAPAFRELAGPVDPEIARHLRPRTLRAMFGTDK 1065
Query: 201 IRNAAHGPDSFASAAREMELFF 222
I+NA H D E+E FF
Sbjct: 1066IKNAVHCTDLPDDGPLEVEYFF 1131
>02656
Length = 2642
Score = 168 bits (426), Expect = 3e-42, Method: Compositional matrix adjust.
Identities = 97/286 (33%), Positives = 152/286 (53%), Gaps = 2/286 (0%)
Frame = +3
Query: 92 EKTLALIKPDAISKAGE-IIEIINKAGFTITKLKMMMLSRKEALDFHVDHQSRPFFNELI 150
++TLALI+PDA + + I+E I +AGF I K + L++++A +F+ +H +P+++EL
Sbjct: 669 QRTLALIRPDAFANNKDAILEKIKEAGFQIALHKEVSLTKEQAEEFYKEHAGQPYYDELT 848
Query: 151 QFITTGPIIAMEILRDDAICEWKRLLGPANSGVARTDASESIRALFGTDGIR-NAAHGPD 209
+++GP++A+ + R+DA+ W+ +LGP + A+T A + +RA F D N HG D
Sbjct: 849 DRMSSGPLLALGLAREDAVENWREMLGPTDVEEAKTAAPDCLRAQFAVDSTAINQLHGSD 1028
Query: 210 SFASAAREMELFFPSSGGCGPANTAKFTNCTCCIVKPHAVSEGLLGKILMAIRDAGFEIS 269
S SA +E+E FFP T ++KP G I+ I AGF I+
Sbjct: 1029STQSAKKELEFFFP-------------VEQTVAMIKPDGY--GTKDAIIEKIHQAGFRIA 1163
Query: 270 AMQMFNMDRVNVEEFYEVYKGVVTEYHDMVTEMYSGPCVAMEIQQNNATKTFREFCGPAD 329
A + + R E FY+ K Y +V M SGP + M + + A +RE GP D
Sbjct: 1164ARKETTITRDIAESFYDDQKDKDY-YESLVEHMTSGPTMFMVLSREGAVDGWREEIGPTD 1340
Query: 330 PEIARHLRPGTLRAIFGKTKIQNAVHCTDLPEDGLLEVRYFFLICD 375
P A+ P +LRA FG +QNAVH E+ +++ F D
Sbjct: 1341PTKAKEQNPNSLRAQFGTDVLQNAVHGASSSEEAKKKIKAVFGDLD 1478
Score = 150 bits (379), Expect = 7e-37, Method: Compositional matrix adjust.
Identities = 92/289 (31%), Positives = 153/289 (52%), Gaps = 9/289 (3%)
Frame = +3
Query: 94 TLALIKPDAIS--KAGEIIEIINKAGFTITKLKMMMLSRKEALDFHVDHQSRPFFNELIQ 151
T+A+IKP+ ++ K EI+ + G + + L+ EA +F+ Q +F +L+
Sbjct: 219 TVAIIKPNVVANGKVDEILAEMKARGINVKAQEERQLTEDEAREFYSHLQGEEYFEDLVA 398
Query: 152 FITTGP---IIAMEILRDDAIC-EWKRLLGPANSGVARTDASESIRALFGTDGIRNAAHG 207
F+ +GP ++ E DD++ +W+ +LGP A+ A ES+RA +G G+ NA HG
Sbjct: 399 FMASGPSHVLVLTEGQEDDSVVKDWRDMLGPPTVEDAKEQAPESLRARYGQGGLMNAVHG 578
Query: 208 PDSFASAAREMELFFPSSGGCGPANTAKFTNCTCCIVKPHAVSEGLLGKILMAIRDAGFE 267
DS +AARE+ FFP K T +++P A + IL I++AGF+
Sbjct: 579 SDSKETAARELAFFFPHMQAPKLQKKKKEVQRTLALIRPDAFANNKDA-ILEKIKEAGFQ 755
Query: 268 ISAMQMFNMDRVNVEEFYEVYKGVVTEYHDMVTE-MYSGPCVAMEIQQNNATKTFREFCG 326
I+ + ++ + EEFY+ + G Y+D +T+ M SGP +A+ + + +A + +RE G
Sbjct: 756 IALHKEVSLTKEQAEEFYKEHAG--QPYYDELTDRMSSGPLLALGLAREDAVENWREMLG 929
Query: 327 PADPEIARHLRPGTLRAIFG--KTKIQNAVHCTDLPEDGLLEVRYFFLI 373
P D E A+ P LRA F T I N +H +D + E+ +FF +
Sbjct: 930 PTDVEEAKTAAPDCLRAQFAVDSTAI-NQLHGSDSTQSAKKELEFFFPV 1073
>02733
Length = 853
Score = 76.3 bits (186), Expect(2) = 4e-15, Method: Compositional matrix adjust.
Identities = 35/110 (31%), Positives = 63/110 (57%)
Frame = -1
Query: 113 INKAGFTITKLKMMMLSRKEALDFHVDHQSRPFFNELIQFITTGPIIAMEILRDDAICEW 172
I++AGF I K ++R A F+ D + + ++ L++ +T+GP + M + R+ A+ W
Sbjct: 742 IHQAGFRIAARKETTITRDIAESFYDDQKDKDYYESLVEHMTSGPTMFMVLSREGAVDGW 563
Query: 173 KRLLGPANSGVARTDASESIRALFGTDGIRNAAHGPDSFASAAREMELFF 222
+ +GP + A+ S+RA FGTD ++NA HG S A ++++ F
Sbjct: 562 REEIGPTDPTKAKEQNPNSLRAQFGTDVLQNAVHGASSSEEAKKKIKAVF 413
Score = 22.3 bits (46), Expect(2) = 4e-15, Method: Compositional matrix adjust.
Identities = 9/19 (47%), Positives = 14/19 (73%)
Frame = -2
Query: 92 EKTLALIKPDAISKAGEII 110
++TLALI+PDA + + I
Sbjct: 807 QRTLALIRPDAFANNKDAI 751
Score = 67.0 bits (162), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 39/111 (35%), Positives = 55/111 (49%)
Frame = -1
Query: 261 IRDAGFEISAMQMFNMDRVNVEEFYEVYKGVVTEYHDMVTEMYSGPCVAMEIQQNNATKT 320
I AGF I+A + + R E FY+ K Y +V M SGP + M + + A
Sbjct: 742 IHQAGFRIAARKETTITRDIAESFYDDQKDK-DYYESLVEHMTSGPTMFMVLSREGAVDG 566
Query: 321 FREFCGPADPEIARHLRPGTLRAIFGKTKIQNAVHCTDLPEDGLLEVRYFF 371
+RE GP DP A+ P +LRA FG +QNAVH E+ +++ F
Sbjct: 565 WREEIGPTDPTKAKEQNPNSLRAQFGTDVLQNAVHGASSSEEAKKKIKAVF 413
>14087
Length = 2025
Score = 33.5 bits (75), Expect(2) = 1e-05, Method: Compositional matrix adjust.
Identities = 15/43 (34%), Positives = 22/43 (51%)
Frame = +3
Query: 333 ARHLRPGTLRAIFGKTKIQNAVHCTDLPEDGLLEVRYFFLICD 375
A+ P +LRA FG +QNAVH E+ +++ F D
Sbjct: 120 AKEQNPNSLRAQFGTDVLQNAVHGASSSEEAKKKIKAVFGDLD 248
Score = 33.1 bits (74), Expect(2) = 1e-05, Method: Compositional matrix adjust.
Identities = 14/36 (38%), Positives = 19/36 (52%)
Frame = +2
Query: 295 YHDMVTEMYSGPCVAMEIQQNNATKTFREFCGPADP 330
Y +V M SGP + M + + A +RE GP DP
Sbjct: 5 YESLVEHMTSGPTMFMVLSREGAVDGWREEIGPTDP 112
Score = 33.9 bits (76), Expect(2) = 1e-05, Method: Compositional matrix adjust.
Identities = 15/50 (30%), Positives = 29/50 (58%)
Frame = +2
Query: 145 FFNELIQFITTGPIIAMEILRDDAICEWKRLLGPANSGVARTDASESIRA 194
++ L++ +T+GP + M + R+ A+ W+ +GP TD ++S RA
Sbjct: 2 YYESLVEHMTSGPTMFMVLSREGAVDGWREEIGP-------TDPTKSQRA 130
Score = 32.3 bits (72), Expect(2) = 1e-05, Method: Compositional matrix adjust.
Identities = 14/32 (43%), Positives = 21/32 (65%)
Frame = +3
Query: 191 SIRALFGTDGIRNAAHGPDSFASAAREMELFF 222
S+RA FGTD ++NA HG S A ++++ F
Sbjct: 141 SLRAQFGTDVLQNAVHGASSSEEAKKKIKAVF 236
>31902
Length = 546
Score = 45.1 bits (105), Expect = 5e-05, Method: Compositional matrix adjust.
Identities = 21/52 (40%), Positives = 29/52 (55%)
Frame = +1
Query: 172 WKRLLGPANSGVARTDASESIRALFGTDGIRNAAHGPDSFASAAREMELFFP 223
W+ +GP + +AR +A SIRA +GTD NA HG DS + + L P
Sbjct: 388 WREAIGPTDPSLARKEAPTSIRAQYGTDVTCNAVHGSDSPGNWPVPLTLRLP 543
Score = 43.1 bits (100), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 25/88 (28%), Positives = 45/88 (51%), Gaps = 1/88 (1%)
Frame = +1
Query: 274 FNMDRVNVEEFYE-VYKGVVTEYHDMVTEMYSGPCVAMEIQQNNATKTFREFCGPADPEI 332
F+++ ++ + + KG + ++ +T ++ PC A + +RE GP DP +
Sbjct: 250 FSLELIHTHKLPTWMMKGTASSWNGTMTCQHA-PC-ASSSSTSPTPSLWREAIGPTDPSL 423
Query: 333 ARHLRPGTLRAIFGKTKIQNAVHCTDLP 360
AR P ++RA +G NAVH +D P
Sbjct: 424 ARKEAPTSIRAQYGTDVTCNAVHGSDSP 507
Score = 33.1 bits (74), Expect = 0.20, Method: Compositional matrix adjust.
Identities = 12/32 (37%), Positives = 19/32 (59%)
Frame = +3
Query: 5 ERFVFIAEWYDPNASLLRRYELLFYPGDGSVE 36
ER+ FI EWYD ++ R++ ++ SVE
Sbjct: 297 ERYSFIVEWYDDMSARTLRFQFFYFTNSKSVE 392
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000270202 | hsapiens_gene_ensembl | RAC-alpha
serine/threonine-protein kinase (EC 2.7.11.1) (RAC-PK-alpha) (Protein
kinase B) (PKB) (C-AKT). [Source:Uniprot/SWISSPROT;Acc:P31749]
(480 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
30755 355 3e-98
18484 173 6e-50
03240 188 5e-48
17722 169 2e-42
18663 145 3e-35
00486 142 2e-34
27405 129 3e-30
31885 116 2e-26
00300 116 2e-26
12721 111 6e-25
09606 108 5e-24
26156 93 1e-23
14420 102 4e-22
15910 100 9e-22
26560 96 2e-20
18921 95 5e-20
13592 95 5e-20
25019 90 2e-18
21079 85 5e-17
01707 83 2e-16
01060 82 3e-16
01392 82 4e-16
14126 80 1e-15
13212 80 3e-15
13066 75 7e-14
28638 58 4e-13
06405 72 7e-13
21808 71 1e-12
21433 70 3e-12
19094 69 3e-12
32957 67 1e-11
29581 67 2e-11
00392 66 3e-11
11185 66 3e-11
01756 65 4e-11
14116 64 1e-10
17975 63 2e-10
38560 63 2e-10
19301 63 2e-10
04591 62 4e-10
04852 62 4e-10
19761 61 1e-09
33586 48 1e-09
27546 60 2e-09
04138 59 3e-09
12786 59 6e-09
26711 58 7e-09
11780 57 1e-08
02638 57 2e-08
01966 56 3e-08
17591 55 4e-08
01718 55 5e-08
17932 44 6e-08
07940 52 4e-07
07291 51 1e-06
17300 50 2e-06
07836 50 2e-06
09007 50 3e-06
03508 49 3e-06
00715 49 6e-06
07833 47 1e-05
28157 47 2e-05
26009 47 2e-05
20152 44 1e-04
11404 44 1e-04
29590 43 2e-04
18996 43 3e-04
20640 43 4e-04
31120 41 0.001
18401 39 0.004
37063 38 0.007
13952 38 0.010
30339 37 0.013
36481 37 0.017
27274 36 0.032
17253 36 0.039
17516 35 0.098
14477 34 0.11
31489 34 0.14
13305 33 0.20
32000 33 0.28
26052 33 0.33
17806 32 0.57
03106 32 0.71
21210 31 1.1
24241 31 1.1
21800 31 1.3
01106 30 1.8
28940 29 3.9
22098 29 4.2
00638 28 7.6
15549 28 8.3
>30755
Length = 1137
Score = 355 bits (910), Expect = 3e-98, Method: Compositional matrix adjust.
Identities = 164/239 (68%), Positives = 194/239 (81%)
Frame = +2
Query: 238 HLSRERVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCK 297
HLS ER+F+E+R RFYGAEI+SAL YLHS+ ++YRDLKLENL+LDKDGHIK+ DFGLCK
Sbjct: 2 HLSHERIFTEERTRFYGAEIISALGYLHSQ-GIIYRDLKLENLLLDKDGHIKVADFGLCK 178
Query: 298 EGIKDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKL 357
E I G T KTFCGTPEYLAPEVL+DNDYGRAVDWWG GVVMYEM+CGRLPFYN+DH+ L
Sbjct: 179 EDITYGRTTKTFCGTPEYLAPEVLDDNDYGRAVDWWGTGVVMYEMICGRLPFYNRDHDVL 358
Query: 358 FELILMEEIRFPRTLGPEAKSLLSGLLKKDPKQRLGGGSEDAKEIMQHRFFAGIVWQHVY 417
F LIL+E+++FPR + EAKSLLSGLL KDP+ RLGGG +D KEI H FFA I W +
Sbjct: 359 FTLILVEDVKFPRNITDEAKSLLSGLLAKDPRNRLGGGQDDVKEIQAHPFFASINWTDLV 538
Query: 418 EKKLSPPFKPQVTSETDTRYFDEEFTAQMITITPPDQDDSMECVDSERRPHFPQFSYSA 476
+KK++PPFKPQVTS+TDTRYFDEEFT + + +TPPD + + E P FPQFSY
Sbjct: 539 QKKITPPFKPQVTSDTDTRYFDEEFTGESVELTPPDPTGPLXSIAEE--PLFPQFSYQG 709
>18484
Length = 635
Score = 173 bits (438), Expect(2) = 6e-50, Method: Compositional matrix adjust.
Identities = 78/164 (47%), Positives = 114/164 (69%)
Frame = +1
Query: 234 ELFFHLSRERVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDF 293
+L + + +E F E A FY AEI L +LH ++ ++YRDLKL+N+MLD +GHIKI DF
Sbjct: 1 DLMYRIQQEGKFKEPVAAFYAAEIAVGLFFLH-DQGIIYRDLKLDNVMLDSEGHIKIADF 177
Query: 294 GLCKEGIKDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQD 353
G+CKEG+ AT +TFCGTP+Y+APE++ Y ++VDWW GV+++EM+ G+ PF +D
Sbjct: 178 GMCKEGMTGDATTRTFCGTPDYIAPEIVLYQPYSKSVDWWAYGVLLFEMLAGQPPFDGED 357
Query: 354 HEKLFELILMEEIRFPRTLGPEAKSLLSGLLKKDPKQRLGGGSE 397
++LF I + +P+ + EA SL GLL K+P +RLG GS+
Sbjct: 358 EDELFSSITDHNVSYPKAMSREAVSLCKGLLMKNPTKRLGCGSK 489
Score = 42.7 bits (99), Expect(2) = 6e-50, Method: Compositional matrix adjust.
Identities = 18/52 (34%), Positives = 27/52 (51%)
Frame = +2
Query: 392 LGGGSEDAKEIMQHRFFAGIVWQHVYEKKLSPPFKPQVTSETDTRYFDEEFT 443
LG ++I H FF IVW + ++ PP+KP++T FD+ FT
Sbjct: 473 LGVVQNGERDIRDHAFFRRIVWDKIKSMEVQPPYKPKITDRRKAENFDKSFT 628
>03240
Length = 1683
Score = 188 bits (477), Expect = 5e-48, Method: Compositional matrix adjust.
Identities = 121/345 (35%), Positives = 179/345 (51%), Gaps = 55/345 (15%)
Frame = -3
Query: 150 FEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRVLQNSRHPF 209
FE +K LG G FG+V L ++ TG YAMK L+K ++ +++VAH E +L + + +
Sbjct: 1285 FEKIKTLGVGAFGEVSLCRKNDTGMLYAMKTLRKSDVLKRNQVAHVKAERDILAEADNEW 1106
Query: 210 LTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYLHSEKN 269
+ L YSFQ H+ L FVM+Y GG+L L R + E ARFY AE+V A++ +H
Sbjct: 1105 VVKLYYSFQDHNYLYFVMDYVPGGDLMGLLIRMEILDEPLARFYVAELVQAIESVH-RMG 929
Query: 270 VVYRDLKLENLMLDKDGHIKITDFGLC---------KEGIKDGA-----TMKTFC----- 310
++RD+K +N+++D++GHIK+TDFGLC K +DG +M+ C
Sbjct: 928 FIHRDIKPDNILIDRNGHIKLTDFGLCTGFRWTHNSKYYQRDGTHARQDSMEVKCQLDEQ 749
Query: 311 -------------------------GTPEYLAPEVLED-NDYGRAVDWWGLGVVMYEMMC 344
GTP Y+APEVL Y DWW +GV+++EM+
Sbjct: 748 CQCEILKPLERRRKREQRCLAHSLVGTPNYIAPEVLSRLGGYTSVCDWWSVGVILFEMLV 569
Query: 345 GRLPFY-NQDHEKLFELILMEE-IRFPR--TLGPEAKSLLSGLLKKDPKQRLGGGSED-- 398
G PFY N E +++I ++ ++ PR L AK L+ RL GS+D
Sbjct: 568 GHPPFYANTPAETQYKVINWKDMLKIPRESNLSQPAKDLI---------LRLCCGSDDRL 416
Query: 399 ----AKEIMQHRFFAGIVWQHVYEKKLSPPFKPQVTSETDTRYFD 439
A EI H FFAG+ ++ + +K PP+ P + TDT FD
Sbjct: 415 GLNGAGEIKTHMFFAGVNFETL--RKQQPPYVPNIRYATDTSNFD 287
>17722
Length = 680
Score = 169 bits (428), Expect = 2e-42, Method: Compositional matrix adjust.
Identities = 82/153 (53%), Positives = 101/153 (66%), Gaps = 4/153 (2%)
Frame = -3
Query: 330 VDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTLGPEAKSLLSGLLKKDPK 389
VDWWG GVVMYEMMCGRLPFYN+DH+ LFELIL++ ++FPR L EAK+LLSGLL K+PK
Sbjct: 678 VDWWGTGVVMYEMMCGRLPFYNRDHDVLFELILLQNVKFPRNLSEEAKTLLSGLLAKNPK 499
Query: 390 QRLGGGSEDAKEIMQHRFFAGIVWQHVYEKKLSPPFKPQVTSETDTRYFDEEFTAQMITI 449
+RLGG D EI H FF I W + KK++PP+KP V S DT+Y EEF + + +
Sbjct: 498 RRLGGSEADVTEIKTHPFFQCINWDDLAAKKITPPWKPDVKSSWDTKYIPEEFAQESLHL 319
Query: 450 TPPDQDDSMECVD----SERRPHFPQFSYSASG 478
TP E +D P+F QFSY S
Sbjct: 318 TPGHDHPLAERLDPISEDAELPYFEQFSYHGSS 220
>18663
Length = 600
Score = 145 bits (367), Expect = 3e-35, Method: Compositional matrix adjust.
Identities = 78/178 (43%), Positives = 106/178 (59%), Gaps = 10/178 (5%)
Frame = +2
Query: 307 KTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPF------YNQDH---EKL 357
TFCGTP Y+APE+L DYG +VDWW LGV++YEM+ GR PF N D + L
Sbjct: 2 STFCGTPNYIAPEILRGEDYGFSVDWWALGVLLYEMLAGRSPFDIAGASENPDQNTEDYL 181
Query: 358 FELILMEEIRFPRTLGPEAKSLLSGLLKKDPKQRLGGGSEDA-KEIMQHRFFAGIVWQHV 416
F++IL + IR PR+L +A S+L G L K+P RLG E A +I+ H FF I W+ +
Sbjct: 182 FQVILEKTIRIPRSLSVKAASVLKGFLNKNPADRLGCHRESAFMDIVNHPFFKVIDWEML 361
Query: 417 YEKKLSPPFKPQVTSETDTRYFDEEFTAQMITITPPDQDDSMECVDSERRPHFPQFSY 474
K++SPPFKP++ S+ D F EFT + + +TP D +DS + F F Y
Sbjct: 362 ERKQVSPPFKPRLDSDRDLANFPIEFTGEPVQLTPDDD----HVIDSIDQSEFEGFEY 523
>00486
Length = 797
Score = 142 bits (359), Expect = 2e-34, Method: Compositional matrix adjust.
Identities = 72/169 (42%), Positives = 101/169 (59%)
Frame = -2
Query: 308 TFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIR 367
TFCGT EY+APE+L +G+AVDWW LG +MY+M+ G PF ++ +K + IL ++
Sbjct: 781 TFCGTIEYMAPEILTRTGHGKAVDWWSLGALMYDMLTGSPPFTAENRKKTIDKILKGKLN 602
Query: 368 FPRTLGPEAKSLLSGLLKKDPKQRLGGGSEDAKEIMQHRFFAGIVWQHVYEKKLSPPFKP 427
P L EA+ L+ LL+K+P +RLGGG +D+ I H+FF W + ++ PPF+P
Sbjct: 601 LPPYLTNEARGLIKKLLRKNPAERLGGGHDDSGPIKDHQFFRNTNWALLALRRAEPPFRP 422
Query: 428 QVTSETDTRYFDEEFTAQMITITPPDQDDSMECVDSERRPHFPQFSYSA 476
VTS+ DT FD +FT Q TP D D DS + F F+Y A
Sbjct: 421 NVTSDEDTSQFDTKFTRQ----TPVDSPDDTILSDSINQ-VFKGFTYIA 290
>27405
Length = 532
Score = 129 bits (324), Expect = 3e-30, Method: Compositional matrix adjust.
Identities = 71/178 (39%), Positives = 107/178 (60%), Gaps = 5/178 (2%)
Frame = -3
Query: 161 FGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRVLQ----NSRHPFLTALKYS 216
FG+V ++ TG+ YAMK L K+ I K L E +L PF+ + Y+
Sbjct: 527 FGEVYGCRKADTGKMYAMKCLDKKRIKMKGGETLALNERIMLSLVSTGEGSPFIVCMTYA 348
Query: 217 FQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLK 276
FQT ++LCF+++ NGG+L +HLS+ VF+E RFY AE++ L+++HS + VVYRDLK
Sbjct: 347 FQTPEKLCFILDLMNGGDLHYHLSQHGVFTEKEVRFYAAEVMLGLEHMHS-RFVVYRDLK 171
Query: 277 LENLMLDKDGHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPEVL-EDNDYGRAVDWW 333
N++LD++GH++I+D GL + K GT Y+APEVL + Y + DW+
Sbjct: 170 PANILLDENGHVRISDLGLACDFSKKKPHASV--GTHGYMAPEVLMKGQAYDSSADWF 3
>31885
Length = 529
Score = 116 bits (290), Expect = 2e-26, Method: Compositional matrix adjust.
Identities = 62/159 (38%), Positives = 94/159 (59%), Gaps = 5/159 (3%)
Frame = -2
Query: 207 HPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYLHS 266
HPFL L Y+FQ + L V++ GG+L +H+ +E F ED +FY ++ LDYL S
Sbjct: 495 HPFLVNLWYAFQDEEDLFMVVDLFLGGDLRYHMQQEVSFREDCVKFYLCQLALVLDYLRS 316
Query: 267 EKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPEVL----- 321
+K +V+RD+K +N++LD+ GH +TDF + + ++D + GT Y+APEV
Sbjct: 315 QK-IVHRDIKPDNILLDEQGHCHVTDFNIATQ-LEDDELATSTSGTRPYMAPEVYGVAIN 142
Query: 322 EDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFEL 360
E YG VDWW LGV ++E++ R PF + L E+
Sbjct: 141 ERRGYGFPVDWWSLGVSLFELLKKRRPFSVHSNTSLHEM 25
>00300
Length = 2318
Score = 116 bits (290), Expect = 2e-26, Method: Compositional matrix adjust.
Identities = 82/262 (31%), Positives = 133/262 (50%), Gaps = 10/262 (3%)
Frame = -1
Query: 156 LGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRVLQNSRHPFLTALKY 215
+G+G FGKV +TG A+K +K + + ++ E ++ + +H L Y
Sbjct: 1634 IGEGQFGKVYTAVNMSTGELMALKEMKFQPNDLQ-QLREMCDEIKIFEGIQHENLVKY-Y 1461
Query: 216 SFQTH-DRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYLHSEKNVVYRD 274
+ H D + MEY + G + + + E R Y EIV A+++LH E ++V+RD
Sbjct: 1460 GVEVHKDEMLMFMEYCDTGTI--EEAAKMGLPEYLIRRYTREIVLAVNHLH-ENSIVHRD 1290
Query: 275 LKLENLMLDKDGHIKITDFGLCKEGIKDGATM----KTFCGTPEYLAPEVLEDND---YG 327
+K N+ L +GH+K+ DFG C +K TM GT Y+APEV ND YG
Sbjct: 1289 IKGANIFLTSNGHVKLGDFG-CSVKLKSHTTMPGEFHNLVGTTAYMAPEVFTQNDQGGYG 1113
Query: 328 RAVDWWGLGVVMYEMMCGRLPFYNQD--HEKLFELILMEEIRFPRTLGPEAKSLLSGLLK 385
RA D W LG V+ EM G+ P+++ D ++ ++++ + + P +L E K L ++
Sbjct: 1112 RAADIWSLGCVVIEMATGKRPWHDLDNNYQIMYKVGIGHKPAVPDSLSVEGKHFLDLIMC 933
Query: 386 KDPKQRLGGGSEDAKEIMQHRF 407
DP QR A +++ H F
Sbjct: 932 HDPAQR-----ALASQLLDHTF 882
>12721
Length = 821
Score = 111 bits (277), Expect = 6e-25, Method: Compositional matrix adjust.
Identities = 75/265 (28%), Positives = 132/265 (49%), Gaps = 3/265 (1%)
Frame = +1
Query: 130 GAEEMEVSLAKPKHRVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAK 189
A +M V+ P R +++F + G+G+ G ++ + GR A +KK + +
Sbjct: 49 AALQMVVTPGDP--RTFLDDFMKI---GEGSTG-IVCIATSRDGRQMA---VKKMDLRKQ 201
Query: 190 DEVAHTLTENRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDR 249
E V+++ HP + + S+ +D L VME+ GG L ++ R+
Sbjct: 202 QRRELLFNEVVVMRDYHHPNIVEMYNSYLVNDELWVVMEFMEGGALTDIVTNNRMDEVQI 381
Query: 250 ARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKTF 309
A A + AL +LH+ V++RD+K ++++L DG +K+ DFG C + +D K+
Sbjct: 382 ATVCRA-CLKALAFLHA-NGVIHRDIKSDSILLSHDGKVKLXDFGFCAQVTQDLQKRKSL 555
Query: 310 CGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELIL---MEEI 366
GTP ++APEV+ YG VD W LG+++ EM+ PF+N+ + I ++
Sbjct: 556 VGTPYWMAPEVISRLPYGPEVDIWSLGIMVMEMIDAEPPFFNEPPLQAMRRIRDMPPPKL 735
Query: 367 RFPRTLGPEAKSLLSGLLKKDPKQR 391
R + P + + +L +DP QR
Sbjct: 736 RNTHKISPRLQGFIDRMLVRDPHQR 810
>09606
Length = 1300
Score = 108 bits (270), Expect = 5e-24, Method: Compositional matrix adjust.
Identities = 83/294 (28%), Positives = 133/294 (45%), Gaps = 30/294 (10%)
Frame = -3
Query: 147 MNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRVLQNSR 206
M F + LGKG + + K T + A+ ++K + EV +T+ R+ +
Sbjct: 1118 MENFVLYEELGKGEHSIIYKGRRKGTINFVAIHCIEK---CKRPEVTNTV---RMTHDIS 957
Query: 207 HPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYLHS 266
HP + ++T + L V+E GG L L+++ E R +G +V+ L Y+HS
Sbjct: 956 HPNVVQFHEWYETSNHLWLVVELCTGGSLADILAQDHHLPETSIRDFGIHLVTGLHYIHS 777
Query: 267 EKNVVYRDLKLENLMLDKDGHIKITDFGLCK-EG------------------IKDGATMK 307
+++ DL+ ++LD G +K DFGL K EG I+ M
Sbjct: 776 -LGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQWNIQSAEEMM 600
Query: 308 T---FCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILME 364
G+P Y+APEV + + D W LG V YEM G PF + ++ + +L +
Sbjct: 599 KQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSGHPPFLGETYDITKDKVLNK 420
Query: 365 EIRFPRTLG--------PEAKSLLSGLLKKDPKQRLGGGSEDAKEIMQHRFFAG 410
E P+ G PE +LL LL+KD +RL S +++H F+ G
Sbjct: 419 EFPLPKVKGSRLSAKPSPEFLNLLESLLQKDSTRRLSWAS-----LVKHAFWQG 273
>26156
Length = 479
Score = 92.8 bits (229), Expect(2) = 1e-23, Method: Compositional matrix adjust.
Identities = 43/112 (38%), Positives = 74/112 (66%), Gaps = 1/112 (0%)
Frame = -1
Query: 142 KHRVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRV 201
++++ + +F L+++G+G++ KV+ V+ K T R YAMK++KKE++ +++ TE V
Sbjct: 407 RNKLGLTDFLLLRVIGRGSYAKVLQVEHKRTKRIYAMKVIKKELVNDDEDIDWVQTEKHV 228
Query: 202 LQN-SRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARF 252
+ + +PFL L FQ+ RL FV+E+ NGG+L FH+ R+R E+ ARF
Sbjct: 227 FETATNYPFLVGLHSCFQSESRLFFVIEFVNGGDLMFHMQRQRRLPEEHARF 72
Score = 35.4 bits (80), Expect(2) = 1e-23, Method: Composition-based stats.
Identities = 16/26 (61%), Positives = 21/26 (80%)
Frame = -3
Query: 252 FYGAEIVSALDYLHSEKNVVYRDLKL 277
FY AEI AL++LH ++ +VYRDLKL
Sbjct: 75 FYSAEICLALNFLH-KRGIVYRDLKL 1
>14420
Length = 528
Score = 102 bits (253), Expect = 4e-22, Method: Compositional matrix adjust.
Identities = 58/172 (33%), Positives = 93/172 (54%)
Frame = +2
Query: 182 KKEVIVAKDEVAHTLTENRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSR 241
KKE+I+ E V++ +++P + S+ + L VME+ GG L +
Sbjct: 29 KKELII---------NEILVMRENQNPNIVNYLDSYLVGEELWVVMEFLAGGSLT-DVVT 178
Query: 242 ERVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIK 301
E E + E + AL++LH E V++RD+K +N++L DG +K+TDFG C +
Sbjct: 179 ETCMDEGQIAAVCRECLQALEFLH-ENQVIHRDIKSDNILLGMDGSVKLTDFGFCAQLSP 355
Query: 302 DGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQD 353
+ + T GTP ++APEV+ YG VD W LGV+ EM+ G P+ N++
Sbjct: 356 EQSKRSTMVGTPYWMAPEVVTRKQYGPTVDIWSLGVMCIEMIEGEPPYLNEN 511
>15910
Length = 1361
Score = 100 bits (250), Expect = 9e-22, Method: Compositional matrix adjust.
Identities = 59/166 (35%), Positives = 94/166 (56%), Gaps = 7/166 (4%)
Frame = +2
Query: 234 ELFFHLSRERVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLM---LDKDGHIKI 290
ELF + ++E A ++I+ + Y+H+ VV+RDLK ENL+ + D +K+
Sbjct: 422 ELFDRIVTRGQYTEKDAARAISDILHGVQYIHA-NGVVHRDLKPENLLYECMTDDSKLKL 598
Query: 291 TDFGLCKEGIKDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFY 350
DFGL + I+ M T CGTP Y APEVL+ + Y +VD W +GV+ Y ++CG PF+
Sbjct: 599 ADFGLSR-IIEPEVQMSTVCGTPGYCAPEVLKGDKYTPSVDMWSVGVIAYILLCGYEPFF 775
Query: 351 NQDHEKLFELILMEEIRFPR----TLGPEAKSLLSGLLKKDPKQRL 392
++ +++ I+ E +F + AK ++ LL DPK+RL
Sbjct: 776 AENEFEMYRKIIKGEYKFDEEYWSEISENAKDVVRKLLVIDPKKRL 913
>26560
Length = 398
Score = 96.3 bits (238), Expect = 2e-20, Method: Compositional matrix adjust.
Identities = 50/127 (39%), Positives = 80/127 (62%), Gaps = 3/127 (2%)
Frame = -1
Query: 234 ELFFHLSRERVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDF 293
+L +HLS+ VF+E RFY AE++ L+++HS + VVYRDLK N++LD++GH++I+D
Sbjct: 398 DLHYHLSQHGVFTEKEVRFYAAEVMLGLEHMHS-RFVVYRDLKPANILLDENGHVRISDL 222
Query: 294 GLCKEGIKDGATMKTFCGTPEYLAPEVL-EDNDYGRAVDWWGLGVVMYEMMCGRLPF--Y 350
GL + K GT Y+APEVL + Y + DW+ G ++Y+++ G PF +
Sbjct: 221 GLACDFSKKRPHASV--GTHGYMAPEVLMKGQSYDSSADWFSFGCMLYKLLKGHSPFRQH 48
Query: 351 NQDHEKL 357
NQ ++
Sbjct: 47 NQGQARI 27
>18921
Length = 697
Score = 95.1 bits (235), Expect = 5e-20, Method: Compositional matrix adjust.
Identities = 66/215 (30%), Positives = 104/215 (48%), Gaps = 1/215 (0%)
Frame = +2
Query: 135 EVSLAKPKHRVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAH 194
E SLA+P V F+ L LG+G++G V K TG+ A+K +V V D +
Sbjct: 2 EESLARPPEDV----FDILGKLGEGSYGSVFKSLHKETGQVLAIK----QVPVDTD-LQE 154
Query: 195 TLTENRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLS-RERVFSEDRARFY 253
+ E ++Q ++ S+ + L VMEY G + + R + E
Sbjct: 155 IIKEISIMQQCDSKYIVKYYGSYFKNTDLWIVMEYCGAGSVSDIMRLRNKTLVEREIATI 334
Query: 254 GAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKTFCGTP 313
+ L YLHS + + +RD+K N++L+ +GH K+ DFG+ + A T GTP
Sbjct: 335 LYYTLKGLXYLHSRRKI-HRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTP 511
Query: 314 EYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLP 348
++APEV+++ Y D W LG+ EM G+ P
Sbjct: 512 YWMAPEVIQEIGYDCVADIWSLGITALEMAEGKPP 616
>13592
Length = 980
Score = 95.1 bits (235), Expect = 5e-20, Method: Compositional matrix adjust.
Identities = 75/266 (28%), Positives = 130/266 (48%), Gaps = 14/266 (5%)
Frame = +2
Query: 156 LGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDE---VAHTLTENRVLQNSRHPFLTA 212
+G+G FGKV TG AMK E+ + E + + E ++L+ +H L
Sbjct: 8 IGQGRFGKVYTAVNNNTGELMAMK----EIAIQPGETRALKNVAEELKILEGIKHKNLVR 175
Query: 213 LKYSFQTH-DRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYLHSEKNVV 271
Y + H + L ME + G L + E +R + A+++S + LH + +V
Sbjct: 176 Y-YGIEVHREELLIFMELCSEGTLESLVELTGGLPEALSRRFTAQLLSGVAELH-KHGIV 349
Query: 272 YRDLKLENLML-DKDGHIKITDFGLCKEGIKDGAT----MKTFCGTPEYLAPEVL---ED 323
+RD+K N+ L D +K+ DFG + I+ T ++ + GT Y+APEV
Sbjct: 350 HRDIKTANIFLVDGSNSLKLGDFGSAVK-IQAHTTVPGELQGYVGTQAYMAPEVFTKTNS 526
Query: 324 NDYGRAVDWWGLGVVMYEMMCGRLPF--YNQDHEKLFELILMEEIRFPRTLGPEAKSLLS 381
+ +GR D W +G V+ EM G+ P+ ++ + + +F++ + E+ + P +L E +
Sbjct: 527 DGHGRLADIWSVGCVVVEMASGKRPWAQFDSNFQIMFKVGMGEKPQAPESLSQEGHDFID 706
Query: 382 GLLKKDPKQRLGGGSEDAKEIMQHRF 407
L+ DPKQRL A E+++ F
Sbjct: 707 HCLQHDPKQRL-----SAIELLEQNF 769
>25019
Length = 730
Score = 90.1 bits (222), Expect = 2e-18, Method: Compositional matrix adjust.
Identities = 37/59 (62%), Positives = 45/59 (76%)
Frame = +3
Query: 278 ENLMLDKDGHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLG 336
EN++LDKDGH+K+TDFGLCKE I TFCGT EY+APE+L +G+AVDWW LG
Sbjct: 261 ENVLLDKDGHVKLTDFGLCKEAITGTRVTHTFCGTIEYMAPEILTRTGHGKAVDWWSLG 437
Score = 50.8 bits (120), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 27/70 (38%), Positives = 41/70 (58%), Gaps = 2/70 (2%)
Frame = +1
Query: 327 GRAVDWWG--LGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTLGPEAKSLLSGLL 384
G A W G G +MY+M+ G PF ++ +K + IL ++ P L EA+ L+ LL
Sbjct: 403 GTARRWTGGVWGALMYDMLTGSPPFTAENRKKTIDKILKGKLNLPPYLTNEARGLIKKLL 582
Query: 385 KKDPKQRLGG 394
+K+P +RLGG
Sbjct: 583 RKNPAERLGG 612
>21079
Length = 878
Score = 85.1 bits (209), Expect = 5e-17, Method: Compositional matrix adjust.
Identities = 49/145 (33%), Positives = 81/145 (55%), Gaps = 3/145 (2%)
Frame = +1
Query: 207 HPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRER-VFSEDRARFYGAEIVSALDYLH 265
HP L L +F+ + VME+ GELF + R+ V +E + +I S + Y+H
Sbjct: 1 HPKLLMLWDAFEAPRTMVLVMEFVGAGELFERVIRDDFVLTERDCVHFVRQICSGVGYMH 180
Query: 266 SEKNVVYRDLKLENLML--DKDGHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPEVLED 323
++ ++++ DLK EN++ D IKI DFGL + K G +++ GTPE++APEV+
Sbjct: 181 TQ-SILHLDLKPENVLCVSDNSNQIKIIDFGLAR-FYKPGDSLQVLFGTPEFIAPEVVNY 354
Query: 324 NDYGRAVDWWGLGVVMYEMMCGRLP 348
++ D W +GV+ Y ++ G P
Sbjct: 355 DEINFTTDMWSIGVICYILLSGLSP 429
>01707
Length = 757
Score = 83.2 bits (204), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 60/204 (29%), Positives = 101/204 (49%), Gaps = 4/204 (1%)
Frame = +1
Query: 147 MNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLT--ENRVLQN 204
M ++E + +G+G++G V + K T + A +KK V D + + E R+L+
Sbjct: 61 MEKYEKIGKIGEGSYGVVFKCRNKETSQLVA---IKKFVESEDDPLIKKIAMREIRMLKQ 231
Query: 205 SRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSR-ERVFSEDRARFYGAEIVSALDY 263
+HP L L F+ RL V +Y + L L R R E + + + A+++
Sbjct: 232 LKHPNLVRLIEVFRRKKRLHLVFDYVDH-TLLNELDRYPRGLPEPMVKRIIYQTLLAVNF 408
Query: 264 LHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPEVL-E 322
H + N ++RD+K EN+++ + G +K+ DFG + G + T Y APE+L
Sbjct: 409 CH-QYNTIHRDVKPENILITRQGQVKLCDFGFARILTGPGDEYTDYVATRWYRAPELLVG 585
Query: 323 DNDYGRAVDWWGLGVVMYEMMCGR 346
D YG VD W +G V E++ G+
Sbjct: 586 DTQYGPPVDVWAIGCVFAELLTGQ 657
>01060
Length = 1800
Score = 82.4 bits (202), Expect = 3e-16, Method: Compositional matrix adjust.
Identities = 79/290 (27%), Positives = 133/290 (45%), Gaps = 34/290 (11%)
Frame = +1
Query: 156 LGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEV-AHTLTENRVLQNSRHPFLTALK 214
+G+GT+G V + +ATGR AMK K + ++D V + + E +L+ RH + L+
Sbjct: 97 IGEGTYGVVYKCRHRATGRKLAMK--KIRLRGSEDGVPSSAIREIAMLRELRHTNIVCLE 270
Query: 215 YSFQTHDRLCFVMEYANGG-ELFFHLSRERVFSEDR-ARFYGAEIVSALDYLHSEKNVVY 272
+RL V E+ + +++ E V + R + Y +IV+ + + H ++ +V+
Sbjct: 271 DVIMEDERLFLVFEFLSMDLKMYIDKFPEGVVLDRRLVKSYVFQIVTGIXFCH-QRRIVH 447
Query: 273 RDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPEVLED-NDYGRAVD 331
RDLK +NL+++ G IKI DFG+ + T Y APE+L + Y VD
Sbjct: 448 RDLKPQNLLINHTGAIKIADFGMARTFALPVRAYTHEVVTLWYRAPEILMGASKYSTPVD 627
Query: 332 WWGLGVVMYEMMCGRLPFYNQDHE-----KLFELI----------------------LME 364
W +G + +M+ R P + D E K+F +I L +
Sbjct: 628 VWSIGTIFADMLI-RTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKLPAFNGMFPLWK 804
Query: 365 EIRFPRT---LGPEAKSLLSGLLKKDPKQRLGGGSEDAKEIMQHRFFAGI 411
E + T L L+ LK DP QR+ K+++QH +F +
Sbjct: 805 EGKLSETLTDLDSLGLDLIERTLKCDPAQRIS-----CKKMLQHAYFLNV 939
>01392
Length = 1806
Score = 82.0 bits (201), Expect = 4e-16, Method: Compositional matrix adjust.
Identities = 62/197 (31%), Positives = 90/197 (45%), Gaps = 32/197 (16%)
Frame = -1
Query: 245 FSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLM---LDKDGHIKITDFGLCKEGIK 301
E A I ALD+LHS K + +RDLK EN++ LD +KI DF L
Sbjct: 1800 LCEREASLVVRHIARALDFLHS-KGIAHRDLKPENILCEHLDDVVPVKICDFDLASGISC 1624
Query: 302 DGATMKTF-----CGTPEYLAPEVLE-----DNDYGRAVDWWGLGVVMYEMMCGRLPFYN 351
DG KT G+ EY+APEV++ Y + D W LG+++Y M+CG PFY
Sbjct: 1623 DGDGTKTPELLTPVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILYIMLCGYPPFYG 1444
Query: 352 QDHEK---------------LFELILMEEIRFPR----TLGPEAKSLLSGLLKKDPKQRL 392
Q E LF I +FP ++ AK L+ LL ++P++R
Sbjct: 1443 QCGEDCGWNRGEACHDCQDMLFNSIQDGHYKFPSQEWTSISSSAKDLIRHLLVREPRKRY 1264
Query: 393 GGGSEDAKEIMQHRFFA 409
A ++++H +
Sbjct: 1263 S-----AADVLKHPWIC 1228
>14126
Length = 1265
Score = 80.5 bits (197), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 70/256 (27%), Positives = 122/256 (47%), Gaps = 18/256 (7%)
Frame = +3
Query: 124 SPSDNSGAEEMEVSLAKPKHRVTMNEFEYLKLLGKGTFGKVILVKE-KATGRYYAMKILK 182
SP G E +++ + T ++E + ++G G +G V ++ + G + AMK ++
Sbjct: 120 SPKGRDGQSESAAKMSR-RRDSTEQKYEEVAVIGNGAYGTVYKARDLRNQGEFVAMKRIR 296
Query: 183 KE------VIVAKDEVAHTLTENRVLQNSRHP-FLTALKYSFQT----HDRLCFVMEYAN 231
++A E++ + L+ HP + L S T RL V EY
Sbjct: 297 LNNTEEGMPMMAIREISML----KQLEQYEHPNVVRLLDVSHNTITDREIRLNLVFEYIE 464
Query: 232 GGELFFHLSR--ERVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIK 289
+L +L++ DR + ++++ +D+LHS + +V+RDLK +NL++ KDG +K
Sbjct: 465 H-DLATYLAKCPSPGLGPDRIKDLMLQLLNGVDFLHSNR-IVHRDLKPQNLLISKDGRLK 638
Query: 290 ITDFGLCKEGIKDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPF 349
+ DFGL + + T T Y +PEVL +YG +VD W G + E+ R F
Sbjct: 639 LADFGLARI-YSFHMALTTVVVTLWYRSPEVLMQAEYGTSVDIWSCGCIFAELFTRRALF 815
Query: 350 YNQDH----EKLFELI 361
+K+FE+I
Sbjct: 816 KGSSEFDQLKKIFEVI 863
>13212
Length = 1067
Score = 79.7 bits (195), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 54/177 (30%), Positives = 86/177 (48%), Gaps = 10/177 (5%)
Frame = -1
Query: 242 ERVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIK 301
E+ +E + + E+ ALD+LH +V++RD+K N++L DG +K+ DFG+ + +
Sbjct: 998 EKPMTEAQICYVCHEMCMALDFLHRH-HVIHRDIKAGNVLLTIDGEVKLADFGVSAKNTQ 822
Query: 302 DGATMKTFCGTPEYLAPEV-----LEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEK 356
TF GTP ++APEV L+D Y D W LGV + E P N++
Sbjct: 821 TQQKRDTFIGTPYWMAPEVVLCETLKDTPYDFKADIWSLGVTLIEFAQIEPP--NKEMHP 648
Query: 357 LFELILMEEIRFPRTLGPEA-----KSLLSGLLKKDPKQRLGGGSEDAKEIMQHRFF 408
+ LI + + P P+ K ++ L KDP R A E+++H F
Sbjct: 647 MRVLIKIHKSDPPTLEKPKKWTKLFKDFIAKCLVKDPNLRPT-----AAELLEHPFM 492
>13066
Length = 551
Score = 74.7 bits (182), Expect = 7e-14, Method: Compositional matrix adjust.
Identities = 41/140 (29%), Positives = 71/140 (50%), Gaps = 4/140 (2%)
Frame = +3
Query: 201 VLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSA 260
+L HP++ + Q + M +A G+L ++ E +A+ + ++ +A
Sbjct: 135 LLTKLDHPYIIQIHSILQRXPKNFIFMRFAERGDLLTYIQEVGFVKEKQAKIWFYQMTTA 314
Query: 261 LDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGA---TMKTFCGTPEYLA 317
L+YLHS +V +RDLK EN++L ++K+ DFG I + +T+CG+ Y A
Sbjct: 315 LNYLHS-YDVAHRDLKCENILLSSHFNVKLADFGFACACITESGEKYMSRTYCGSAAYAA 491
Query: 318 PEVLEDNDYG-RAVDWWGLG 336
PE++ Y + D W LG
Sbjct: 492 PEIVYGAPYAPKVADAWSLG 551
>28638
Length = 1458
Score = 57.8 bits (138), Expect(2) = 4e-13, Method: Compositional matrix adjust.
Identities = 36/107 (33%), Positives = 56/107 (52%), Gaps = 3/107 (2%)
Frame = -1
Query: 246 SEDRARFYGAEIVSALDYLHS-EKNVVYRDLKLENLML--DKDGHIKITDFGLCKEGIKD 302
S + R + ++ +AL +L + E N+++ DLK EN++L K IKI DFG +
Sbjct: 843 SLNLTRKFAQQLCTALLFLATPEMNIIHCDLKPENILLCNPKRSAIKIVDFG---SSCQL 673
Query: 303 GATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPF 349
G + + + Y +PEVL Y A+D W LG ++ EM G P
Sbjct: 672 GQRIYQYIQSRFYRSPEVLLGVPYDLAIDMWSLGCILVEMHTGEPPL 532
Score = 34.7 bits (78), Expect(2) = 4e-13, Method: Compositional matrix adjust.
Identities = 24/85 (28%), Positives = 45/85 (52%), Gaps = 3/85 (3%)
Frame = -3
Query: 147 MNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILK-KEVIVAKDEVAHTLTE--NRVLQ 203
++ +E L+GKG+FG+V+ + A+KI+K K+ + + ++ L E NR
Sbjct: 1150 LDRYEIDSLIGKGSFGQVVKAYDHGDQEQVAIKIIKNKKPFLNQAQIEVKLLELMNRHDA 971
Query: 204 NSRHPFLTALKYSFQTHDRLCFVME 228
++ + ++ LK F + LC V E
Sbjct: 970 DNXY-YIVRLKRHFMFRNHLCLVFE 899
>06405
Length = 1965
Score = 71.6 bits (174), Expect = 7e-13, Method: Compositional matrix adjust.
Identities = 58/210 (27%), Positives = 94/210 (44%), Gaps = 4/210 (1%)
Frame = +1
Query: 156 LGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRVLQNSRHPFLTALKY 215
LG G +G V K + A+K LK++ + D L E +++ +HP L L
Sbjct: 283 LGGGQYGDVYEAMWKRYNKIVAVKTLKEDTMALND----FLEEAAIMKEMKHPNLVQLLG 450
Query: 216 SFQTHDRLCFVMEYANGGELFFHL-SRERVFSEDRARFYGA-EIVSALDYLHSEKNVVYR 273
V E+ G L +L S R + A Y A +I S + YL + KN ++R
Sbjct: 451 VCTREPPFYIVTEFMPHGNLLDYLRSSTREENGPTALMYMATQIASGMAYLET-KNFIHR 627
Query: 274 DLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKTFCGTP-EYLAPEVLEDNDYGRAVDW 332
DL N ++ +K+ DFGL + D T P ++ APE L N + D
Sbjct: 628 DLAARNCLVADSNMVKVADFGLARLMKDDTYTAHIGAKFPIKWTAPEGLAFNRFSTRSDI 807
Query: 333 WGLGVVMYEMMC-GRLPFYNQDHEKLFELI 361
W GV+++E+ G P+ + +++ L+
Sbjct: 808 WAFGVLLWELATYGMSPYPGVELTEVYHLL 897
>21808
Length = 1011
Score = 70.9 bits (172), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 53/177 (29%), Positives = 85/177 (48%), Gaps = 4/177 (2%)
Frame = +1
Query: 177 AMKILKKEVIVAKDEVAHTLTENRVLQNSRHPFLTALKYSFQTHDRLCFVME--YANGGE 234
A+K LK + KD L E ++++ RHP L L Y+ T D F++ NG
Sbjct: 31 AIKTLKSGTMDPKD----FLAEAQIMKKLRHPKLIQL-YAVCTQDDPIFIITELMKNGSL 195
Query: 235 LFFHLSRERVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFG 294
L F + RV GA+I + YL S+ N ++RDL N+++ + +KI DFG
Sbjct: 196 LEFLQGKGRVLKLPALIDIGAQIACGMAYLESQ-NYIHRDLAARNILVSDNNTVKIADFG 372
Query: 295 LCKEGIKDGATMKTFCGTP-EYLAPEVLEDNDYGRAVDWWGLGVVMYEMMC-GRLPF 349
L + +D + P ++ APE N + D W G+++ E + GR+P+
Sbjct: 373 LARVIKEDEYEARVGARFPIKWTAPEAANYNRFTIKSDVWSFGILLTETVTYGRVPY 543
>21433
Length = 590
Score = 69.7 bits (169), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 51/142 (35%), Positives = 70/142 (49%), Gaps = 1/142 (0%)
Frame = +2
Query: 249 RARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKT 308
R Y ++ SAL+Y H K V++RD+K ENL+L G +KI DFG T T
Sbjct: 170 RTACYIYQLSSALEYCHYRK-VIHRDIKPENLLLGLKGDLKIADFGWSVHAPSSRRT--T 340
Query: 309 FCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRF 368
CGT +YL PE++E + VD W LGV+ YE + G P
Sbjct: 341 MCGTLDYLPPEMVEGKTHDENVDLWSLGVLCYEFLVGTPPLRPSPTRPPTPASPRWTSGS 520
Query: 369 PRTLGPEAKSLLSGLLK-KDPK 389
P + P A+ L+S LL+ + PK
Sbjct: 521 PSIVTPGARDLISKLLRHRSPK 586
>19094
Length = 898
Score = 69.3 bits (168), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 34/90 (37%), Positives = 52/90 (57%)
Frame = +1
Query: 258 VSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKTFCGTPEYLA 317
+ L YLHS + + +RD+K N++L+ +GH K+ DFG+ + A T GTP ++A
Sbjct: 88 LKGL*YLHSRRKI-HRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTPYWMA 264
Query: 318 PEVLEDNDYGRAVDWWGLGVVMYEMMCGRL 347
PEV+++ Y D W LG+ EM G L
Sbjct: 265 PEVIQEIGYDCVADIWSLGITALEMAEGNL 354
>32957
Length = 645
Score = 67.0 bits (162), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 28/55 (50%), Positives = 40/55 (72%)
Frame = +3
Query: 293 FGLCKEGIKDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRL 347
F LC E K G +TFCGT EY+APEV E +YG+ VDWWGLG++++E++ ++
Sbjct: 3 FALCVE--KSGGRTRTFCGTREYMAPEVHERKEYGKEVDWWGLGILLHELLAAQI 161
>29581
Length = 1278
Score = 66.6 bits (161), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 45/145 (31%), Positives = 70/145 (48%), Gaps = 3/145 (2%)
Frame = -2
Query: 202 LQNSRHPFLTALKYSF--QTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVS 259
L N RH + L+ ++ D L VMEY + FSE + + +++
Sbjct: 1193 LLNLRHQNIVQLQEVVVGKSLDSLFLVMEYCEQDLASLLDNMPAPFSESQVKCIVLQLLK 1014
Query: 260 ALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPE 319
L YLH E +++RDLK+ NL++ G +KI DFGL + K M T Y APE
Sbjct: 1013 GLRYLH-EAFIIHRDLKVSNLLMTDKGCVKIADFGLARNYGKPQKPMTPKVVTLWYRAPE 837
Query: 320 VL-EDNDYGRAVDWWGLGVVMYEMM 343
+L + A+D W G ++ E++
Sbjct: 836 LLFGSKTHSTAIDMWSAGCILGELL 762
>00392
Length = 668
Score = 66.2 bits (160), Expect = 3e-11, Method: Compositional matrix adjust.
Identities = 45/159 (28%), Positives = 81/159 (50%), Gaps = 7/159 (4%)
Frame = +3
Query: 198 ENRVLQNSRHPFLTALKYSFQTHDR-----LCFVMEYANGGELFFHLSRERVFSEDRARF 252
E +L+ +HP + ++ H+ + V E G L +L R + + +
Sbjct: 81 EAEMLKELQHPNIVRFFDYWEEHNHRNRKVIILVTELMTSGTLKTYLKRFKKPNVKILKN 260
Query: 253 YGAEIVSALDYLHSEKN-VVYRDLKLENLMLD-KDGHIKITDFGLCKEGIKDGATMKTFC 310
+ +++ L +LH+ V++RDLK +N+ + G +KI D GL +K+ + K+
Sbjct: 261 WCRQVLKGLYFLHTRTPPVIHRDLKCDNIFITGPTGSVKIGDLGL--ATLKNQSFAKSVI 434
Query: 311 GTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPF 349
GTPE++APE+ E++ Y AVD + G+ M EM P+
Sbjct: 435 GTPEFMAPEMYEEH-YDEAVDVYAFGMCMLEMASSEYPY 548
>11185
Length = 473
Score = 65.9 bits (159), Expect = 3e-11, Method: Compositional matrix adjust.
Identities = 52/180 (28%), Positives = 75/180 (41%), Gaps = 22/180 (12%)
Frame = +1
Query: 251 RFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCK-EG---------- 299
R +G +V+ L Y+HS +++ DL+ ++LD G +K DFGL K EG
Sbjct: 10 RDFGIHLVTGLHYIHS-LGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKF 186
Query: 300 --------IKDGATMKT---FCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLP 348
I+ M G+P Y+APEV + + D W LG V YEM G
Sbjct: 187 AEAGDQWNIQSAEEMMKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSGS-- 360
Query: 349 FYNQDHEKLFELILMEEIRFPRTLGPEAKSLLSGLLKKDPKQRLGGGSEDAKEIMQHRFF 408
R PE +LL LL+KD +RL S +++H F+
Sbjct: 361 ------------------RLSAKPSPEFLNLLESLLQKDSTRRLSWAS-----LVKHAFW 471
>01756
Length = 1858
Score = 65.5 bits (158), Expect = 4e-11, Method: Compositional matrix adjust.
Identities = 55/209 (26%), Positives = 96/209 (45%), Gaps = 15/209 (7%)
Frame = -3
Query: 149 EFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLT---ENRVLQNS 205
++E L +G+GTFG+V + K T + AMK +V++ ++ +T E ++LQ
Sbjct: 1739 KYEKLAKIGQGTFGEVFKARCKKTKQVVAMK----KVLMDNEKEGFPITALREIKILQLL 1572
Query: 206 RHPFLTALKYSFQTH--------DRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEI 257
H + L T V E+ + VF+ + ++
Sbjct: 1571 NHENVVDLIEICSTKATSANRYKSMFYLVFEFCEHDLAGLLSNMSVVFNLPEIKEVMKQL 1392
Query: 258 VSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKE---GIKDGATMKTFCGTPE 314
++ L Y+H K +++RD+K N+++ K G +K+ DFGL + ++ T
Sbjct: 1391 MNGLYYIHRNK-ILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLW 1215
Query: 315 YLAPE-VLEDNDYGRAVDWWGLGVVMYEM 342
Y PE +L D +Y A+D WG G +M EM
Sbjct: 1214 YRPPELLLGDRNYSTAIDQWGAGCIMAEM 1128
>14116
Length = 1017
Score = 64.3 bits (155), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 55/201 (27%), Positives = 94/201 (46%), Gaps = 13/201 (6%)
Frame = -1
Query: 156 LGKGTFGKV----ILVKEKATGRYYAMKILK----KEVIVAKDEVAHTLTENRVLQNSRH 207
+GKG FG V + + E+ A+K L +E+ E+ L E ++++ H
Sbjct: 612 IGKGNFGCVKRGFLTLPEQKGDILVAVKTLHNNNPREI-----ELQSFLQEALIMKDFHH 448
Query: 208 P-FLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARF-YGAEIVSALDYLH 265
LT + D V+ + G+L ++ ++ + YG +I +DYL
Sbjct: 447 SNVLTLIGICLNLDDMPLVVLPFMKHGDLLTYIRDDQHQPTIKDLIMYGVDIARGMDYLA 268
Query: 266 SEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKD---GATMKTFCGTPEYLAPEVLE 322
K V+RDL N MLD+D H+K+ DFGL ++ + + K +++A E LE
Sbjct: 267 GLK-FVHRDLAARNCMLDEDFHVKVADFGLARDIYEKEYYSSENKKAKLPVKWMALESLE 91
Query: 323 DNDYGRAVDWWGLGVVMYEMM 343
+Y D W GVV++E++
Sbjct: 90 KGNYDSKTDVWSYGVVLWELL 28
>17975
Length = 449
Score = 63.2 bits (152), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 46/139 (33%), Positives = 78/139 (56%), Gaps = 4/139 (2%)
Frame = +3
Query: 161 FGKVILVKEKATGRYYAMKILKKEVIVAKDEVA--HTLTENRVLQNSRHPFLTALKYSFQ 218
F V L + TG A+K++ K + DEV+ H E R ++ +HP + L
Sbjct: 6 FAVVKLARHVFTGEKVAVKVIDKTKL---DEVSRSHLFQEVRCMKLVQHPNVVRLYEVID 176
Query: 219 THDRLCFVMEYANGGELFFHLSRERVFSEDR-ARFYGAEIVSALDYLHSEKNVVYRDLKL 277
T +L ++E +GG+++ ++ R E++ A+ Y +IV A+ Y H + +VV+RDLK
Sbjct: 177 TQTKLYLILELGDGGDMYDYIMRHSGGLEEKLAKRYFRQIVEAISYCH-KLHVVHRDLKP 353
Query: 278 ENLM-LDKDGHIKITDFGL 295
EN++ +K G +K+TDFG
Sbjct: 354 ENVVFFEKPGLVKLTDFGF 410
>38560
Length = 479
Score = 63.2 bits (152), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 34/117 (29%), Positives = 56/117 (47%), Gaps = 1/117 (0%)
Frame = -3
Query: 306 MKTFCGTPEYLAPEVLEDNDY-GRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILME 364
+ T CG+P Y APE++ +Y G D W +GV++Y ++CG LPF ++ L +
Sbjct: 414 LTTCCGSPAYAAPELISGLEYLGSEADIWSMGVLLYALLCGYLPFDDEKXSHL*QKNQKR 235
Query: 365 EIRFPRTLGPEAKSLLSGLLKKDPKQRLGGGSEDAKEIMQHRFFAGIVWQHVYEKKL 421
+ P L + LL G+L+ DP R+ + F + W Y++ L
Sbjct: 234 KDEVPEWLSEDTTKLLEGMLQTDPSHRITIRRLLDHHWLNQGFNVPVEWASKYKRTL 64
>19301
Length = 712
Score = 63.2 bits (152), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 53/199 (26%), Positives = 87/199 (43%)
Frame = +2
Query: 96 REEWTTAIQTVADGLKKQEEEEMDFRSGSPSDNSGAEEMEVSLAKPKHRVTMNEFEYLKL 155
R WT + A LK+Q++ E+ F S + + E+L
Sbjct: 230 RPVWTIIGKAAAAELKQQDDWEIPFES------------------------ITDLEWL-- 331
Query: 156 LGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRVLQNSRHPFLTALKY 215
G G G V L G+ A ++ K+V K+ T+ R L+ HP + + K
Sbjct: 332 -GSGAQGAVFL------GKLCAEEVAVKKVRDIKE------TDIRNLRKLNHPNIISFKG 472
Query: 216 SFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYLHSEKNVVYRDL 275
C +MEY G+L+ L + + +I S ++YLHS K +++RDL
Sbjct: 473 VCTQAPCYCIIMEYCPYGQLYEVLRDGKEIPPALVLDWSKQIASGMNYLHSHK-IIHRDL 649
Query: 276 KLENLMLDKDGHIKITDFG 294
K N+++ K+ +KI+DFG
Sbjct: 650 KSPNVLVAKNDVVKISDFG 706
>04591
Length = 1117
Score = 62.4 bits (150), Expect = 4e-10, Method: Compositional matrix adjust.
Identities = 39/120 (32%), Positives = 69/120 (57%), Gaps = 2/120 (1%)
Frame = -2
Query: 225 FVMEYANGGELFFHLSRERV-FSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLD 283
+ EY + +L L+ RV FS + +++++ L Y+H+ K +++RD+K N++L
Sbjct: 966 LIFEYCDY-DLAGLLNNLRVKFSLADKKNLMSQLLNGLFYIHT-KQILHRDIKAANILLT 793
Query: 284 KDGHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPE-VLEDNDYGRAVDWWGLGVVMYEM 342
+DG +K+ DFGL + +K + T Y PE +L + +YG +D WG+G +M EM
Sbjct: 792 RDGVLKLADFGLSRPWVKS-KRLTNRVVTLWYRPPELLLGEREYGPEIDMWGVGCIMAEM 616
>04852
Length = 1462
Score = 62.0 bits (149), Expect = 4e-10, Method: Compositional matrix adjust.
Identities = 41/128 (32%), Positives = 70/128 (54%), Gaps = 2/128 (1%)
Frame = +1
Query: 253 YGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKTFCGT 312
Y +I +++L S K ++RDL N+++ ++ +KI DFGL + G D ++
Sbjct: 340 YAFQIARGMEFLASRK-CIHRDLAARNVLVTEEHVLKIADFGLSRTG--DYYKKRSGGRL 510
Query: 313 P-EYLAPEVLEDNDYGRAVDWWGLGVVMYEMMC-GRLPFYNQDHEKLFELILMEEIRFPR 370
P +++APE L D Y D W GVV++E+ G +P+ + +E+L+ +L + R PR
Sbjct: 511 PVKWMAPEALFDMRYTTKSDVWSFGVVLWEIFSLGGMPYASIPNEELYSKLLDDAYRMPR 690
Query: 371 TLGPEAKS 378
PE S
Sbjct: 691 ---PELAS 705
>19761
Length = 473
Score = 61.2 bits (147), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 33/90 (36%), Positives = 53/90 (58%), Gaps = 3/90 (3%)
Frame = -3
Query: 256 EIVSALDYLHSEKNVV-YRDLKLENLMLDKDGHIKITDFGLCKE--GIKDGATMKTFCGT 312
+ SAL+Y+H+ V+ +RDLK +N+ + + G +++ D GL ++ G D AT + GT
Sbjct: 399 QTASALNYMHTHTPVILHRDLKPQNIYVTEKGDVRLGDLGLARKLTGPADFATSQV--GT 226
Query: 313 PEYLAPEVLEDNDYGRAVDWWGLGVVMYEM 342
YL+PE+L Y D W LG V Y++
Sbjct: 225 IMYLSPEILSQQPYNSKSDIWSLGCVFYDI 136
>33586
Length = 551
Score = 48.1 bits (113), Expect(2) = 1e-09, Method: Compositional matrix adjust.
Identities = 21/49 (42%), Positives = 34/49 (69%)
Frame = +2
Query: 209 FLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEI 257
F+ L Y+FQT +L ++E+ GG+LF LS+E +F+E+ +FY AE+
Sbjct: 404 FIVHLHYAFQTEGKLYLILEFLRGGDLFTRLSKEVMFTEEDVKFYLAEL 550
Score = 32.3 bits (72), Expect(2) = 1e-09, Method: Compositional matrix adjust.
Identities = 20/61 (32%), Positives = 32/61 (52%)
Frame = +3
Query: 152 YLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRVLQNSRHPFLT 211
+ ++L KG + I ++ G YAMK+LKK + +D T E +L + HPFL
Sbjct: 240 WTRILWKGVLVRKITGED--AGTLYAMKVLKKATLKVRDR-QRTKMERDILADVNHPFLL 410
Query: 212 A 212
+
Sbjct: 411 S 413
Score = 28.5 bits (62), Expect = 5.7, Method: Compositional matrix adjust.
Identities = 10/17 (58%), Positives = 16/17 (94%)
Frame = +1
Query: 148 NEFEYLKLLGKGTFGKV 164
++FE LK+LG+G+FG+V
Sbjct: 214 SQFELLKVLGQGSFGRV 264
>27546
Length = 426
Score = 60.1 bits (144), Expect = 2e-09, Method: Composition-based stats.
Identities = 33/109 (30%), Positives = 56/109 (51%)
Frame = -1
Query: 198 ENRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEI 257
E +L HP + + Q ++ M YA G++ H+ + E + + + ++
Sbjct: 330 ELEILTRLDHPNIIQIHSILQRGPKIFIFMRYAEKGDMLSHIKKTGPIDEAQTKVWFFQM 151
Query: 258 VSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATM 306
AL YLHS ++ +RDLK EN++L K ++KI DFG + +D A M
Sbjct: 150 AKALQYLHSH-DIAHRDLKCENILLSKRLNVKIADFGFARY-CRDAAGM 10
>04138
Length = 800
Score = 59.3 bits (142), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 59/201 (29%), Positives = 84/201 (41%), Gaps = 40/201 (19%)
Frame = +1
Query: 261 LDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKE---GIKDGATMKTFCGTPEYLA 317
L Y+H K +++RD+K N+++ K G +K+ DFGL + ++ T Y
Sbjct: 52 LYYIHRNK-ILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRP 228
Query: 318 PE-VLEDNDYGRAVDWWGLGVVMYEM---------------------MCG---------- 345
PE +L D +Y A+D WG G +M EM +CG
Sbjct: 229 PELLLGDRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQNQLTLITQLCGSITPEVWPGV 408
Query: 346 -RLPFYNQDHEKLF---ELILMEEIRFPRTL-GPEAKSLLSGLLKKDPKQRLGGGSEDAK 400
+L Y+Q L + I+ + RF R L P L LLK DP QR+ A
Sbjct: 409 TQLSMYHQIKGALAAGRKNIIRD--RFARILKDPYGLDLFERLLKMDPSQRI-----SAD 567
Query: 401 EIMQHRFFAGIVWQHVYEKKL 421
E + H FF W V K L
Sbjct: 568 EALNHDFF----WVGVEPKSL 618
>12786
Length = 460
Score = 58.5 bits (140), Expect = 6e-09, Method: Compositional matrix adjust.
Identities = 39/121 (32%), Positives = 60/121 (49%), Gaps = 22/121 (18%)
Frame = -3
Query: 251 RFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATM--KT 308
+FY E++ A+ LH+E V++ DLK N ML G++K+ DFG+ +D ++ +
Sbjct: 401 KFYWREMLRAVKALHNE-GVIHSDLKPANFMLVA-GNLKLIDFGIANTLQQDKTSVLKDS 228
Query: 309 FCGTPEYLAPEVL-------------EDN-------DYGRAVDWWGLGVVMYEMMCGRLP 348
GTP Y++PE + ED G D W LG ++Y M+ GR P
Sbjct: 227 RVGTPSYMSPEAIMAACDDSADDSMEEDGHRTKPKYKVGVRSDVWSLGCILYNMVYGRTP 48
Query: 349 F 349
F
Sbjct: 47 F 45
>26711
Length = 405
Score = 58.2 bits (139), Expect = 7e-09, Method: Composition-based stats.
Identities = 35/98 (35%), Positives = 57/98 (58%), Gaps = 4/98 (4%)
Frame = -2
Query: 256 EIVSALDYLHSEKNVVYRDLKLENLML--DKDGHIKITDFGLCKEGIKDGATMKTFC--G 311
+++ L ++H++ VV+ DLK NL+L DK +++ DFGL + K +TF G
Sbjct: 392 QVLDILQHVHAQ-GVVHMDLKPSNLLLSGDKLDSVQLIDFGLAR---KLYPPQETFLNHG 225
Query: 312 TPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPF 349
TP + +PE L+ A D WG+GV+ Y ++ G+ PF
Sbjct: 224 TPGFTSPEALDVKPISTASDVWGVGVLAYILLSGQSPF 111
>11780
Length = 1713
Score = 57.4 bits (137), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 64/219 (29%), Positives = 98/219 (44%), Gaps = 10/219 (4%)
Frame = +3
Query: 125 PSDNSGAEEMEVSLAKPKHR---VTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKIL 181
P G VSL + K + + E + +GKG FG V K G+ A+K L
Sbjct: 519 PVTKQGGNFGTVSLQEFKSGGWVIAXQDLEIGEAIGKGDFGDV--YKGMYRGQPVAIKQL 692
Query: 182 KKEVIVAKDEVAHT-LTENRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHL- 239
K KD + L E V+ + RH L L + + V E+ G L +L
Sbjct: 693 KD-----KDRGEQSFLQEASVMTSLRHDNLVRL-IGVVLGETIFLVTEFMGKGNLVEYLR 854
Query: 240 --SRERVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCK 297
R + +D+ F + +A++YL S K +V+RDL N+++ DG K++DFGL K
Sbjct: 855 SRGRSVITKKDQINF-ATDTCAAMEYLES-KRLVHRDLAARNVLVHDDGKAKVSDFGLAK 1028
Query: 298 EGIKDGATMKTFCGTPEYLAPEVLEDNDYG---RAVDWW 333
G ++K ++ APE L +N R V+ W
Sbjct: 1029FGDFSQTSVKF---PIKWTAPEALRENKIH*QVRHVELW 1136
>02638
Length = 1490
Score = 57.0 bits (136), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 33/103 (32%), Positives = 48/103 (46%), Gaps = 5/103 (4%)
Frame = +1
Query: 311 GTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELIL-----MEE 365
GT ++APEVL YGRA D W +G VM EM R P+ + D LI ++
Sbjct: 22 GTIAFMAPEVLRGESYGRACDVWSVGCVMIEMCTCRPPWNSHDISNHLALIFKIASSVDP 201
Query: 366 IRFPRTLGPEAKSLLSGLLKKDPKQRLGGGSEDAKEIMQHRFF 408
P + P + L+ L++D R AK+++ H F
Sbjct: 202 PPIPENMSPPVRDLMLRCLEQDSDFR-----PSAKDLLMHPLF 315
>01966
Length = 1735
Score = 56.2 bits (134), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 46/157 (29%), Positives = 81/157 (51%), Gaps = 3/157 (1%)
Frame = -1
Query: 168 KEKATGRYYAMKILKKEVIVAKDEV-AHTLTENRVLQNSRHPFLTALKYSFQTHDRLCFV 226
+ +ATGR AMK K + ++D V + + E +L+ RH + L+ +RL V
Sbjct: 1651 RHRATGRKLAMK--KIRLRGSEDGVPSSAIREIAMLRELRHTNIVCLEDVIMEDERLFLV 1478
Query: 227 MEYANGG-ELFFHLSRERVFSEDR-ARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDK 284
E+ + +++ E V + R + Y +IV+ +++ H ++ +V+RDLK +NL+++
Sbjct: 1477 FEFLSMDLKMYIDKFPEGVVLDRRLVKSYVFQIVTGINFCH-QRRIVHRDLKPQNLLINH 1301
Query: 285 DGHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPEVL 321
G IKI DFG+ + T Y APE+L
Sbjct: 1300 TGAIKIADFGMARTFALPVRAYTHEVVTLWYRAPEIL 1190
>17591
Length = 474
Score = 55.5 bits (132), Expect = 4e-08, Method: Compositional matrix adjust.
Identities = 26/72 (36%), Positives = 42/72 (58%)
Frame = +3
Query: 376 AKSLLSGLLKKDPKQRLGGGSEDAKEIMQHRFFAGIVWQHVYEKKLSPPFKPQVTSETDT 435
A++ L ++ ++RLG D +EI + FFA I W +Y KK+ PP+ P V+ + D
Sbjct: 111 AETSLKSC*RRRKEERLGA-KRDFEEIQEKAFFADINWDDLYNKKVQPPYNPNVSGQLDL 287
Query: 436 RYFDEEFTAQMI 447
R+FD EF + +
Sbjct: 288 RHFDPEFVREPV 323
Score = 37.0 bits (84), Expect = 0.017, Method: Compositional matrix adjust.
Identities = 18/55 (32%), Positives = 32/55 (58%)
Frame = +2
Query: 340 YEMMCGRLPFYNQDHEKLFELILMEEIRFPRTLGPEAKSLLSGLLKKDPKQRLGG 394
+EM+ G PFY++D +++E IL + +R + +++L LLKK+ GG
Sbjct: 2 FEMLYGLPPFYSRDTSEMYENILYKPLRLRTNVSAAGRNILEELLKKEKGGETGG 166
>01718
Length = 959
Score = 55.5 bits (132), Expect = 5e-08, Method: Compositional matrix adjust.
Identities = 58/213 (27%), Positives = 93/213 (43%), Gaps = 20/213 (9%)
Frame = +3
Query: 156 LGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENR--------VLQNSRH 207
+G G F +V V + TG+ A+K+ +T+T NR +L +H
Sbjct: 171 IGAGFFSEVFKVTHRITGQVMALKM-------------NTMTSNRHNMLREVQLLNRLQH 311
Query: 208 P----FLTALKYSFQTHDRLCFVMEYANGGEL--FFHLSRERVFSEDRARFYGAEIVSAL 261
F+ + Q H + EY G L E + R + + L
Sbjct: 312 ANILRFMGVCVHEGQLHA----LTEYIPSGNLEQLLEKKDEELPWTQRIQLTLG-LARGL 476
Query: 262 DYLHSEKNVVYRDLKLENLML---DKDG-HIKITDFGLCKEGIKDGATMKTF--CGTPEY 315
DYLHS + ++RDL +N+++ D G H I DFGL + I D + G+P +
Sbjct: 477 DYLHSTR-FIHRDLTSKNILIRREDNHGYHAVIADFGLATK-IPDPLDKEKLPTVGSPYW 650
Query: 316 LAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLP 348
+APEVL + Y D + +G++M E+ R+P
Sbjct: 651 MAPEVLNGHFYNERADLFSVGIIMCEIT-ARIP 746
>17932
Length = 597
Score = 43.9 bits (102), Expect(2) = 6e-08, Method: Compositional matrix adjust.
Identities = 26/66 (39%), Positives = 37/66 (56%)
Frame = -3
Query: 375 EAKSLLSGLLKKDPKQRLGGGSEDAKEIMQHRFFAGIVWQHVYEKKLSPPFKPQVTSETD 434
EA+ L+S LL D K RLG E+ QH FF + W ++ + PP+ P ++S D
Sbjct: 451 EARDLISQLLS-DGKSRLGW-----PELQQHPFFKTVDWANI--RNAMPPYVPSISSLDD 296
Query: 435 TRYFDE 440
T +FDE
Sbjct: 295 TSHFDE 278
Score = 30.8 bits (68), Expect(2) = 6e-08, Method: Compositional matrix adjust.
Identities = 12/22 (54%), Positives = 14/22 (63%)
Frame = -2
Query: 332 WWGLGVVMYEMMCGRLPFYNQD 353
WW LGV YEM+ G PF + D
Sbjct: 596 WWSLGVCAYEMLFGCTPFTDDD 531
>07940
Length = 1336
Score = 52.4 bits (124), Expect = 4e-07, Method: Compositional matrix adjust.
Identities = 35/111 (31%), Positives = 58/111 (52%), Gaps = 3/111 (2%)
Frame = -3
Query: 253 YGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKTFCG- 311
Y ++ ++YL S K ++RDL N+++ ++ +KI DFGL + + KT G
Sbjct: 332 YAYQVARGMEYLAS-KQCIHRDLAARNVLVAEEYVLKIADFGLTRNLQQFDYYRKTTDGR 156
Query: 312 -TPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMC-GRLPFYNQDHEKLFEL 360
+++APE L D Y D W GV+++E+ G P+ + E LF L
Sbjct: 155 LPVKWMAPEALFDRKYTSKSDVWSYGVLLWEIFTLGGNPYPSVPVEDLFNL 3
>07291
Length = 833
Score = 51.2 bits (121), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 33/146 (22%), Positives = 73/146 (50%), Gaps = 7/146 (4%)
Frame = +1
Query: 253 YGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKTFCGT 312
+G +I + YL E VV+R+L N ++ +DG ++++D+G+ G + T +
Sbjct: 64 FGRQIADGMAYLQ-EVKVVHRNLAARNCIVTEDGRLQLSDYGVT--GSLFPQSYYTADDS 234
Query: 313 P-----EYLAPEVLEDNDYGRAVDWWGLGVVMYEMMC-GRLPFYNQDHEKLFELILM-EE 365
P +++APE +++ + D W GVV++E++ G P+ + ++ L +
Sbjct: 235 PARDLVKWMAPETIDNFHFSSKSDVWAFGVVLWELLTRGITPYPDVENSSLLPYLKEGHR 414
Query: 366 IRFPRTLGPEAKSLLSGLLKKDPKQR 391
++ P+ +++ + P+QR
Sbjct: 415 MKKPKQSPEPVYEMMTACWNESPEQR 492
>17300
Length = 480
Score = 50.1 bits (118), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 30/101 (29%), Positives = 52/101 (51%), Gaps = 5/101 (4%)
Frame = +1
Query: 266 SEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKD---GATMKTFCGTP-EYLAPEVL 321
++ V+RDL N+++++ K+ DFGL +E D GA P + APE +
Sbjct: 25 ADMGYVHRDLAARNILVNEILVCKVADFGLSREIESDTTEGAYTTKGGKIPVRWTAPEAI 204
Query: 322 EDNDYGRAVDWWGLGVVMYEMMC-GRLPFYNQDHEKLFELI 361
+ A D W GVVM+E+M G P++N ++ + + +
Sbjct: 205 AYRKFTSASDVWSFGVVMWEVMSYGERPYWNWSNQDVIKAV 327
>07836
Length = 1478
Score = 49.7 bits (117), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 49/167 (29%), Positives = 76/167 (45%), Gaps = 29/167 (17%)
Frame = -1
Query: 222 RLCFVMEYANGGELF-FHLSRERVFSEDRARFYGAEIVSALDYLHSE-------KNVVYR 273
+L + +Y G L + LSR SE A + A + L +LH E + +R
Sbjct: 1331 QLFLITDYHENGSLHDYLLSRVLDSSEMLALAHSA--ICGLAHLHIEIFGTRGKPAIAHR 1158
Query: 274 DLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKTFC----GTPEYLAPEVLE------D 323
D+K +N+++ K+G I D GL I + + GT Y+APEVLE +
Sbjct: 1157 DIKSKNILVKKNGTCCIADLGLAVRYISESNEVDVAPNPRQGTKRYMAPEVLEMLLNVKN 978
Query: 324 NDYGRAVDWWGLGVVMYEMM-CG---------RLPFYN-QDHEKLFE 359
D + D + G+VM+E+ C ++PFYN H+ FE
Sbjct: 977 FDAFKQADMYAFGLVMWEIARCCVIGGVAEEYQVPFYNCLPHDPSFE 837
>09007
Length = 1440
Score = 49.7 bits (117), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 58/240 (24%), Positives = 97/240 (40%), Gaps = 14/240 (5%)
Frame = -1
Query: 136 VSLAKPKHRVTMNEFEYLKLLGKGTFGKV---ILVKEKATGRYYAMKILKKEVIVAKDEV 192
V A+ K ++ + K LG+G FG V I E A+K L K+ I +
Sbjct: 915 VRPARGKQLISKDCVALSKSLGQGHFGTVRQAIWTAESGEKVQVAVKCLSKDKI--HKDG 742
Query: 193 AHTLTENRVLQNSRHPFLTAL-KYSFQTHDRLCFVMEYANGGELF---FHLSRERVFSED 248
L E ++Q H + + + V E A L +S FS
Sbjct: 741 QEFLKETAIMQMLDHENIVRVYGVVMDNGADIMLVTELAPMRSLLECVKEVSARVDFSVP 562
Query: 249 RARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLC------KEGIKD 302
R + ++ + YL S K +V+RDL N++L +KI+D G+ KE +
Sbjct: 561 RLCDFSQQVCDGMSYLES-KRLVHRDLAARNILLFSKSKVKISDVGVSGALGAGKEYYQS 385
Query: 303 GATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMC-GRLPFYNQDHEKLFELI 361
T+ + APE + + A D W GV+++E G P+ + +++ E +
Sbjct: 384 QQTIH-LQNAVAWCAPESFRNLCFSSASDVWAFGVLLWEFFTHGFQPWAGLNGQQIMEAV 208
>03508
Length = 1463
Score = 49.3 bits (116), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 32/109 (29%), Positives = 57/109 (52%), Gaps = 2/109 (1%)
Frame = +1
Query: 243 RVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDG-HIKITDFGLCKEGIK 301
+ F++ RFY E++ ALD+ HS +++RD+K N+M+D + +++ D+GL E
Sbjct: 856 QTFTDYDIRFYLYELMKALDFCHS-MGIMHRDVKPHNVMIDHENKKLRLIDWGLA-EFYH 1029
Query: 302 DGATMKTFCGTPEYLAPEVLEDND-YGRAVDWWGLGVVMYEMMCGRLPF 349
G + + PE+L D Y ++D W LG + M+ + P
Sbjct: 1030PGMEYNVRVASRYFKGPELLLDYQMYDYSLDMWSLGCMFASMIFRKEPL 1176
>00715
Length = 1788
Score = 48.5 bits (114), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 32/116 (27%), Positives = 50/116 (43%), Gaps = 22/116 (18%)
Frame = +1
Query: 256 EIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATM--------- 306
++ L YLHS N+V+ DLK N +L +D ++I DFG C + G M
Sbjct: 262 QMARGLHYLHS-INIVHLDLKPANCLLTRDLKLRIADFGCCHQLTPTGLDMGEREGGMAG 438
Query: 307 -------------KTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPF 349
GT Y APE+L+ D + LG+ +++M + P+
Sbjct: 439 NELELTPVQGAWKNELAGTLAYRAPELLKGLQPSVRSDVYSLGITLWQMCTRQGPY 606
>07833
Length = 1504
Score = 47.4 bits (111), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 40/193 (20%), Positives = 84/193 (43%), Gaps = 8/193 (4%)
Frame = -3
Query: 207 HPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRER--VFSEDRARFYGAEIVSALDYL 264
HP + + L + ++ G L+ L E V ++++ + +I +++L
Sbjct: 1442 HPNVLPVLACCNQPPNLVLISQFMPFGSLYNTLHGESGIVVDQNQSLRFAMDIARGMEFL 1263
Query: 265 HS-EKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPEVLE- 322
HS E + L +++M+D+D +I C + G +P ++APE L+
Sbjct: 1262 HSMEPTIPNFLLTSKHVMIDEDLTARINMADYCFSFHEKGKVY-----SPAWMAPEALQR 1098
Query: 323 --DNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIR--FPRTLGPEAKS 378
D+ RA D W ++M+E+ +PF ++ + +E +R P +
Sbjct: 1097 RPDDINTRAADMWSFAILMWELETREVPFAELSSMEVGMKVALEGLRISIPPGISLHMSR 918
Query: 379 LLSGLLKKDPKQR 391
L+ + ++P +R
Sbjct: 917 LIKICMNEEPGKR 879
>28157
Length = 400
Score = 47.0 bits (110), Expect = 2e-05, Method: Composition-based stats.
Identities = 37/115 (32%), Positives = 59/115 (51%), Gaps = 6/115 (5%)
Frame = +3
Query: 186 IVAKDEVAHTLTENRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELF--FHLS-RE 242
I ++ E + E + L HP + L + + H +C VMEYA GG L+ H S +
Sbjct: 24 IESEQEKKSFMQELKQLSRVSHPNIVCLYGACRDHP-VCLVMEYAEGGSLYNVLHGSGPQ 200
Query: 243 RVFSEDRARFYGAEIVSALDYLH--SEKNVVYRDLKLENLMLDKDG-HIKITDFG 294
++ A + + ++YLH K +++RDLK NL+L + G +KI DFG
Sbjct: 201 PQYTAAHAMNWLLQCALGVEYLHGMKPKALIHRDLKPPNLLLIQCGTKLKICDFG 365
>26009
Length = 886
Score = 46.6 bits (109), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 45/185 (24%), Positives = 84/185 (45%), Gaps = 5/185 (2%)
Frame = +2
Query: 91 ETPEEREEWTTAIQTVADGLKKQEEEEMDFRSGSPSDNSGAEEMEVSLAKPKHRVTMNEF 150
E E TT + DG + + +E+ R+ S SDN ++L+ +H +
Sbjct: 284 EVAVEESSATTVVSNQDDGGRGESKEDRSPRN-STSDNL------LTLSLREH------Y 424
Query: 151 EYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKD-----EVAHTLTENRVLQNS 205
+ K LG+GT+GKV+L + + TG A+K+L K ++ ++++ L+ + +
Sbjct: 425 DVCKELGRGTYGKVVLARCRHTGTQVALKLLPKSCTKLREFQREFQLSYFLSPHANI--- 595
Query: 206 RHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYLH 265
+ +FQT F E+A G+LF + ++ E R + E LH
Sbjct: 596 ----IDTYNVAFQTRSSYVFAQEHAVLGDLFDAIPPQQGMRESRGQIR-HETARVRARLH 760
Query: 266 SEKNV 270
+++ V
Sbjct: 761 AQQAV 775
Score = 36.2 bits (82), Expect = 0.028, Method: Compositional matrix adjust.
Identities = 17/50 (34%), Positives = 29/50 (58%)
Frame = +3
Query: 233 GELFFHLSRERVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLML 282
G R + A+ ++VSALD++HS K +V+RD+K EN+++
Sbjct: 666 GTCLTPSRRNKACGSREAKSVMKQLVSALDFMHS-KQLVHRDIKPENVLI 812
>20152
Length = 445
Score = 44.3 bits (103), Expect = 1e-04, Method: Composition-based stats.
Identities = 21/75 (28%), Positives = 40/75 (53%), Gaps = 1/75 (1%)
Frame = +1
Query: 318 PEVLEDNDY-GRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTLGPEA 376
PE+L + Y AVD W LGV++Y ++ G PF + + +I+ + P + +
Sbjct: 1 PEILLGDSYDAPAVDVWSLGVILYMLVVGEAPFQEANDSETLTMIMDCRYQIPPHISHKC 180
Query: 377 KSLLSGLLKKDPKQR 391
+ L+ +L+++P R
Sbjct: 181 QDLIEKMLQREPVDR 225
>11404
Length = 563
Score = 43.9 bits (102), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 39/142 (27%), Positives = 74/142 (52%), Gaps = 7/142 (4%)
Frame = +1
Query: 148 NEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILK-KEVIVAKDEVAHTLTE--NRVLQN 204
+ +E L+GKG+FG+V+ + A+KI+K K+ + + ++ L E NR +
Sbjct: 139 DRYEIDSLIGKGSFGQVVKAYDHTDNEQVAIKIIKNKKPFLNQAQIEVKLLEMMNRHDTD 318
Query: 205 SRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVF---SEDRARFYGAEIVSAL 261
+++ ++ LK F LC V E + + L R F S + R + ++ +AL
Sbjct: 319 NKY-YIVRLKRHFMFRSHLCLVFELLSYN--LYDLLRNTNFRGVSLNLTRKFAQQLCTAL 489
Query: 262 DYLHS-EKNVVYRDLKLENLML 282
+L + E ++++ DLK EN++L
Sbjct: 490 LFLATPEMSIIHCDLKPENILL 555
>29590
Length = 320
Score = 43.1 bits (100), Expect = 2e-04, Method: Composition-based stats.
Identities = 19/47 (40%), Positives = 26/47 (55%)
Frame = +3
Query: 303 GATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPF 349
G ++ GTP+Y+APEVL+ D W LGV+ Y M+ PF
Sbjct: 36 GEDIRDIIGTPDYVAPEVLDYEPLSIQTDMWSLGVLSYVMLTACSPF 176
>18996
Length = 491
Score = 42.7 bits (99), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 25/85 (29%), Positives = 43/85 (50%), Gaps = 7/85 (8%)
Frame = +2
Query: 271 VYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKTFCGTPE------YLAPEVLEDN 324
++RDL N+++D+ +KI+DFGL + DG + G + + +PE +E
Sbjct: 2 IHRDLAARNILVDRSC-VKISDFGLAQFANADG----YYYGISQRDIPIKWYSPEAIETC 166
Query: 325 DYGRAVDWWGLGVVMYEMMC-GRLP 348
+ D W GV ++EM G +P
Sbjct: 167 KFSSYSDVWSYGVTLFEMFSRGEIP 241
>20640
Length = 1492
Score = 42.7 bits (99), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 32/132 (24%), Positives = 56/132 (42%), Gaps = 8/132 (6%)
Frame = +1
Query: 268 KNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKTFCGTPEYLAP------EVL 321
+ V+RDL N ++ D +KI+DFGL + ++ + G+ P E +
Sbjct: 1 RGYVHRDLATRNCLVGHDLVVKISDFGLA----RSVHSVDYYRGSEHDAIPIRWMPLEAI 168
Query: 322 EDNDYGRAVDWWGLGVVMYEMMCGRL-PFYNQDHEKLFELILMEEI-RFPRTLGPEAKSL 379
N + D W GVV++E+ L P+Y HE++ + ++ P P L
Sbjct: 169 LYNKFSTQSDVWSFGVVLWEIFAFALQPYYGLTHEEVVRFVKEGKVLACPERTPPPMYEL 348
Query: 380 LSGLLKKDPKQR 391
+ + P R
Sbjct: 349 MKQCWHRRPATR 384
>31120
Length = 439
Score = 40.8 bits (94), Expect = 0.001, Method: Composition-based stats.
Identities = 22/68 (32%), Positives = 37/68 (54%), Gaps = 4/68 (5%)
Frame = +1
Query: 328 RAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTL----GPEAKSLLSGL 383
+ D W LGV+++ M+ G++PF + + KL E ++ F R L P A+S +S L
Sbjct: 31 KMADAWSLGVILFIMLNGKMPFDDSNLNKLLEDQRSKKYSFRRKLQDLVSPNARSTVSVL 210
Query: 384 LKKDPKQR 391
L+ + R
Sbjct: 211 LEPNSAMR 234
>18401
Length = 463
Score = 38.9 bits (89), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 28/84 (33%), Positives = 39/84 (46%)
Frame = -3
Query: 308 TFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIR 367
T T Y APEV+ + + D W +G +M+E+ G F Q H+ L +ME
Sbjct: 455 TIVSTRHYRAPEVILELGWSHPCDVWSVGCIMFELYTGYTLF--QTHDNKEHLAMME--- 291
Query: 368 FPRTLGPEAKSLLSGLLKKDPKQR 391
R LG SL + KK KQ+
Sbjct: 290 --RILG----SLPYRMAKKTKKQK 237
>37063
Length = 455
Score = 38.1 bits (87), Expect = 0.007, Method: Composition-based stats.
Identities = 28/78 (35%), Positives = 39/78 (50%), Gaps = 13/78 (16%)
Frame = -2
Query: 275 LKLENLM---LDKDGHIKITDFGLCKEGIKDGATMKTF-----CGTPEYLAPEVL----- 321
LK EN++ LD+ +KI DF L DG KT G+ EY+APEV+
Sbjct: 454 LKPENILCEHLDEVVPLKICDFDLASGINCDGDGTKTPELLTPVGSAEYMAPEVVDAWVG 275
Query: 322 EDNDYGRAVDWWGLGVVM 339
E Y + D W LG+++
Sbjct: 274 ESFSYDKRCDMWSLGIIL 221
>13952
Length = 577
Score = 37.7 bits (86), Expect = 0.010, Method: Compositional matrix adjust.
Identities = 24/79 (30%), Positives = 38/79 (48%)
Frame = -3
Query: 7 VKEGWLHKRGEYIKTWRPRYFLLKNDGTFIGYKERPQDVDQREAPLNNFSVAQCQLMKTE 66
VKEGWL K+G K W+ R+F+L ND ++ + PL N V + + +
Sbjct: 419 VKEGWLMKQGGRYKNWKRRWFIL-NDNCLYYFQYTADKEPKGIIPLENIQVRE---LSEK 252
Query: 67 RPRPNTFIIRCLQWTTVIE 85
R N F + + + VI+
Sbjct: 251 SSRSNAFELYSVSGSDVIK 195
>30339
Length = 384
Score = 37.4 bits (85), Expect = 0.013, Method: Composition-based stats.
Identities = 18/52 (34%), Positives = 30/52 (57%)
Frame = -2
Query: 120 FRSGSPSDNSGAEEMEVSLAKPKHRVTMNEFEYLKLLGKGTFGKVILVKEKA 171
R+ SPS + G + R +++F ++K+LGKG+FGKV+L + K
Sbjct: 131 LRARSPSSDRG---------RSSDRFHLHDFNFIKVLGKGSFGKVMLAERKG 3
>36481
Length = 806
Score = 37.0 bits (84), Expect = 0.017, Method: Compositional matrix adjust.
Identities = 39/153 (25%), Positives = 67/153 (43%), Gaps = 16/153 (10%)
Frame = +2
Query: 146 TMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILK-----KEVIVAKDEVAHTLTENR 200
+ N+ + G+GTFGKV+ K+ G A+KI+K +E + V L E
Sbjct: 356 STNDMKLCPHWGEGTFGKVVQCKDLLKGDDIALKIIKNVDKYREAAKLEINVLEKLREKD 535
Query: 201 VLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGA----- 255
+++H + L + F H +C + FH+ VF + YGA
Sbjct: 536 --PHAKHMCVQMLDW-FDYHGHVC----------ISFHMLGLSVFDFLKDNSYGAYPIEQ 676
Query: 256 ------EIVSALDYLHSEKNVVYRDLKLENLML 282
++ A+++LH E + + DLK EN++
Sbjct: 677 VRHISYQLCYAVNFLH-ENQLTHTDLKPENILF 772
>27274
Length = 396
Score = 36.2 bits (82), Expect = 0.032, Method: Composition-based stats.
Identities = 12/31 (38%), Positives = 21/31 (67%)
Frame = -1
Query: 319 EVLEDNDYGRAVDWWGLGVVMYEMMCGRLPF 349
E+L +G VD W LG++++E++ G +PF
Sbjct: 375 ELLRGQQHGPTVDMWSLGILLHELLSGHVPF 283
>17253
Length = 483
Score = 35.8 bits (81), Expect = 0.039, Method: Compositional matrix adjust.
Identities = 26/104 (25%), Positives = 44/104 (42%), Gaps = 11/104 (10%)
Frame = -1
Query: 206 RHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRER----VFSEDRAR------FYGA 255
RHP + + D +ME+ G+L L + R VF A F+
Sbjct: 372 RHPNVVSFMGCCTMSDPALILMEFCCHGDLLSFLRKRRPDRTVFLTSTANDLTARDFFSF 193
Query: 256 EIVSALDYLHSEKN-VVYRDLKLENLMLDKDGHIKITDFGLCKE 298
+ A H N +V+RD+ N+++ + K++DFGL +
Sbjct: 192 ALHVARGMAHVANNKIVHRDVAARNVLISERNVCKVSDFGLSRR 61
>17516
Length = 453
Score = 34.7 bits (78), Expect = 0.098, Method: Composition-based stats.
Identities = 15/40 (37%), Positives = 24/40 (60%), Gaps = 1/40 (2%)
Frame = -3
Query: 308 TFCGTPEYLAPEV-LEDNDYGRAVDWWGLGVVMYEMMCGR 346
T GTP Y+APEV L+ Y D + L ++++E+ G+
Sbjct: 442 TLAGTPVYMAPEVLLQKGQYDMKADVYSLAIILWELWYGQ 323
>14477
Length = 493
Score = 34.3 bits (77), Expect = 0.11, Method: Compositional matrix adjust.
Identities = 39/160 (24%), Positives = 69/160 (43%), Gaps = 6/160 (3%)
Frame = -1
Query: 144 RVTMNEFEYLKLLGKGTFGKVILVKEKATGRY------YAMKILKKEVIVAKDEVAHTLT 197
++ M+E + LG G FG V+ K R A+K+LK + + + +
Sbjct: 490 QIQMDELK----LGAGNFGSVM----KGVCRLDDREIPVAIKVLKNADLDPSVQ-SELIK 338
Query: 198 ENRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEI 257
E V++ H + L + + V+E A G L L + + ++
Sbjct: 337 EAEVMKKMDHMHIVRL-IGLCEGETMMLVLELAKLGPLNKFLPKNKHLPLWNILELMWQV 161
Query: 258 VSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCK 297
++YL + K V+RDL N++L + KI+DFG+ K
Sbjct: 160 SQGMEYLEANK-FVHRDLAARNILLCDEHFAKISDFGMSK 44
>31489
Length = 329
Score = 33.9 bits (76), Expect = 0.14, Method: Composition-based stats.
Identities = 16/40 (40%), Positives = 27/40 (67%)
Frame = +3
Query: 242 ERVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLM 281
++ +E+ R++ +I+ L Y+HS NVV+RDLK NL+
Sbjct: 147 DQPLTEEHIRYFLYQILRGLKYIHS-ANVVHRDLKPSNLL 263
>13305
Length = 549
Score = 33.5 bits (75), Expect = 0.20, Method: Compositional matrix adjust.
Identities = 16/48 (33%), Positives = 27/48 (56%), Gaps = 1/48 (2%)
Frame = +2
Query: 315 YLAPEVLEDNDYGRAVDWWGLGVVMYEMMC-GRLPFYNQDHEKLFELI 361
++A E L +N Y D W GVV++E+ G P+ + D ++LF +
Sbjct: 23 WMAVESLFNNTYTTQSDVWSFGVVLWEIFTLGGTPYSSTDTQQLFAFL 166
>32000
Length = 644
Score = 33.1 bits (74), Expect = 0.28, Method: Compositional matrix adjust.
Identities = 32/105 (30%), Positives = 48/105 (45%), Gaps = 5/105 (4%)
Frame = -1
Query: 286 GHIKITDFGLCKEGIKDGATMKTFCG---TPEYLAPEVLEDND-YGRAVDWWGLGVVMYE 341
+KI DFGL + G ++T+ T Y APE+L Y VD W LG + E
Sbjct: 578 AKMKIADFGLARVF---GLPVRTYTHEVITLWYRAPEILLGCRFYSVPVDIWSLGCIFVE 408
Query: 342 MMCGRLPFY-NQDHEKLFELILMEEIRFPRTLGPEAKSLLSGLLK 385
MM R F + + ++L+ + RTLG + + G+ K
Sbjct: 407 MMTRRALFPGDSEIDQLYRIF--------RTLGTPDEKVWPGVSK 297
>26052
Length = 562
Score = 32.7 bits (73), Expect = 0.33, Method: Compositional matrix adjust.
Identities = 18/53 (33%), Positives = 30/53 (56%)
Frame = -1
Query: 127 DNSGAEEMEVSLAKPKHRVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMK 179
+N ++M S+ P ++ + KLLG G+FGKV+ ++ K TG A+K
Sbjct: 436 NNQYHQKMASSMCLPX------QYLFXKLLGVGSFGKVMALQHKDTGETLAVK 296
>17806
Length = 433
Score = 32.0 bits (71), Expect = 0.57, Method: Compositional matrix adjust.
Identities = 36/144 (25%), Positives = 57/144 (39%), Gaps = 10/144 (6%)
Frame = +1
Query: 132 EEMEVSLAKPKHRVTMNEFEYLKLLGKGTFGKVI-----LVKEKATGRYYAMKILKKEVI 186
E+ + + H ++ YLK LG G FGKVI + + +K+LK +
Sbjct: 1 EDASLKMIAGHHPFPRSQIVYLKELGTGWFGKVIESDAERITTGVSRSKVVVKMLKDD-- 174
Query: 187 VAKDEVAHTLTENRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRER--- 243
KDE E + HP + L + + +ME A G L +L R
Sbjct: 175 ATKDEQLLFFEEVAPFRELDHPNIVRLLGQCTEMNPMLMLMECAALGNLKQYLRNHRHQQ 354
Query: 244 --VFSEDRARFYGAEIVSALDYLH 265
+ ++R + +I S L LH
Sbjct: 355 AMLIQKNRLLKFAMDISSGLACLH 426
>03106
Length = 2384
Score = 31.6 bits (70), Expect = 0.71, Method: Compositional matrix adjust.
Identities = 22/70 (31%), Positives = 33/70 (47%), Gaps = 3/70 (4%)
Frame = +2
Query: 325 DYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTLG--PE-AKSLLS 381
DY +A D W G V YE+ PFY++ + + P G PE L++
Sbjct: 17 DYSKA-DVWAAGAVAYEIFGASNPFYSRLDSACY-----SQHDLPSLPGDTPEGVVRLVT 178
Query: 382 GLLKKDPKQR 391
+L++DP QR
Sbjct: 179 SMLERDPAQR 208
>21210
Length = 518
Score = 31.2 bits (69), Expect = 1.1, Method: Compositional matrix adjust.
Identities = 14/43 (32%), Positives = 22/43 (51%), Gaps = 4/43 (9%)
Frame = +3
Query: 311 GTPEYLAPEVLE----DNDYGRAVDWWGLGVVMYEMMCGRLPF 349
G Y+APE ++ + Y D W LG+ + E+ GR P+
Sbjct: 6 GCRPYMAPERIDPRASSHGYDVRSDVWSLGITLMELATGRFPY 134
>24241
Length = 413
Score = 31.2 bits (69), Expect = 1.1, Method: Compositional matrix adjust.
Identities = 26/84 (30%), Positives = 43/84 (51%), Gaps = 2/84 (2%)
Frame = -2
Query: 150 FEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEV-AHTLTENRVLQNSRHP 208
+ L +G+GT+G V + +ATGR AMK K + ++D V + + E +L+ RH
Sbjct: 337 LDRLSKIGEGTYGVVYKCRHRATGRKLAMK--KIRLRGSEDGVPSSAIREIAMLRELRHT 164
Query: 209 -FLTALKYSFQTHDRLCFVMEYAN 231
L L+ +RL V E+ +
Sbjct: 163 QXLVCLEDVIMEDERLFLVFEFLS 92
>21800
Length = 855
Score = 30.8 bits (68), Expect = 1.3, Method: Compositional matrix adjust.
Identities = 10/30 (33%), Positives = 23/30 (76%)
Frame = +2
Query: 256 EIVSALDYLHSEKNVVYRDLKLENLMLDKD 285
+++ L+YLH++ N+++ D+K EN+++ D
Sbjct: 656 QVLEGLNYLHAKCNIIHTDIKPENILICVD 745
>01106
Length = 878
Score = 30.4 bits (67), Expect = 1.8, Method: Compositional matrix adjust.
Identities = 32/147 (21%), Positives = 66/147 (44%), Gaps = 11/147 (7%)
Frame = +3
Query: 150 FEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKE---VIVAKDEVA--HTLTENRVLQN 204
+ ++ LG G F V L + R+ A+K++K A DEV + E+ V
Sbjct: 324 YHVIRKLGWGHFSTVWLCWDLTCKRFVALKVVKSAQHYTETALDEVKLLKCVRESDVADP 503
Query: 205 SRHPFLTALKYSFQ------THDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIV 258
+R + L F+ TH + F + N +L + + + + + +++
Sbjct: 504 ARAKCVQLLD-DFKISGVNGTHVAMVFEVLGYNLLKLIIRSNYQGIPIHN-VKLIIRQVL 677
Query: 259 SALDYLHSEKNVVYRDLKLENLMLDKD 285
L Y+H++ +++ D+K EN+++ D
Sbjct: 678 EGLSYMHAKCRIIHTDIKPENILICVD 758
>28940
Length = 875
Score = 29.3 bits (64), Expect = 3.9, Method: Compositional matrix adjust.
Identities = 12/25 (48%), Positives = 17/25 (68%)
Frame = +2
Query: 183 KEVIVAKDEVAHTLTENRVLQNSRH 207
KEV+ KDE HT + ++LQ +RH
Sbjct: 227 KEVLHGKDESKHTFSSEKLLQTNRH 301
>22098
Length = 1090
Score = 28.9 bits (63), Expect = 4.2, Method: Compositional matrix adjust.
Identities = 15/40 (37%), Positives = 23/40 (57%), Gaps = 5/40 (12%)
Frame = +2
Query: 309 FCGTPEYLAPEVLE-----DNDYGRAVDWWGLGVVMYEMM 343
GT Y+APEVLE + D +D + G+V++E+M
Sbjct: 14 LVGTRRYMAPEVLEGAICFNRDSFLRIDMYACGLVLWELM 133
>00638
Length = 1595
Score = 28.1 bits (61), Expect = 7.6, Method: Compositional matrix adjust.
Identities = 13/34 (38%), Positives = 23/34 (67%)
Frame = +2
Query: 243 RVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLK 276
+ F++ RFY E++ ALD+ HS +++RD+K
Sbjct: 401 QTFTDYDIRFYLYELMKALDFCHS-MGIMHRDVK 499
>15549
Length = 470
Score = 28.1 bits (61), Expect = 8.3, Method: Compositional matrix adjust.
Identities = 13/32 (40%), Positives = 20/32 (62%)
Frame = -1
Query: 148 NEFEYLKLLGKGTFGKVILVKEKATGRYYAMK 179
+EFE ++ +GKG +G V K K + YA+K
Sbjct: 218 DEFECIEQMGKGGYGIVFRAKNKVDEQEYAVK 123
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000290100 | hsapiens_gene_ensembl | Protein 4.1
(Band 4.1) (P4.1) (EPB4.1) (4.1R).
[Source:Uniprot/SWISSPROT;Acc:P11171]
(775 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
00990 345 3e-95
18811 187 1e-47
11374 177 1e-44
17332 115 6e-26
28244 79 7e-15
08363 68 1e-11
03469 65 7e-11
13951 52 1e-06
05888 49 6e-06
12829 32 1.2
>00990
Length = 3161
Score = 345 bits (886), Expect = 3e-95, Method: Compositional matrix adjust.
Identities = 157/282 (55%), Positives = 212/282 (75%), Gaps = 2/282 (0%)
Frame = +3
Query: 226 VETWLDSAKEIKKQVRGVPWNFTFNVKFYPPDPAQLTEDITRYYLCLQLRQDIVAGRLPC 285
++ WL K I KQ +G PW F F +KFYPPDP QL E +TR+ + LQ R+DI++G+LP
Sbjct: 420 LKCWLSPDKRISKQKKGGPWLFDFALKFYPPDPTQLRESLTRWLVVLQTRRDILSGKLPA 599
Query: 286 SFATLALLGSYTIQSELGDYDPELH-GVDYVSDFKLAPNQTKELEEKVMELHKSYRSMTP 344
++ T A+LGSY +Q+++GDYDP H GV+Y+ D APNQT +L EK++ELH+ ++ TP
Sbjct: 600 TYLTQAMLGSYCVQADVGDYDPNEHRGVEYIRDTPFAPNQTIDLLEKIVELHRQHKGQTP 779
Query: 345 AQADLEFLENAKKLSMYGVDLHKAKDLEGVDIILGVCSSGLLVYKDKLRINRFPWPKVLK 404
+A+ FLENAKKL+MYGVDLH A+D+ VDI+LGVC+SGL VY++KLRI+RF WPK+LK
Sbjct: 780 DEAETNFLENAKKLAMYGVDLHAAQDVNNVDIMLGVCASGLQVYREKLRISRFVWPKILK 959
Query: 405 ISYKRSSFFIKIRPGEQEQYESTIGFKLPSYRAAKKLWKVCVEHHTFFRLTSTD-TIPKS 463
ISYKR F+IK+RP + E++ FKL ++R AK+LWK+CVEHH FFRL + + +
Sbjct: 960 ISYKRRQFYIKVRPSDNSAMENSFCFKLATHRLAKRLWKICVEHHAFFRLREAEQSQNAA 1139
Query: 464 KFLALGSKFRYSGRTQAQTRQASALIDRPAPHFERTASKRAS 505
F LGSKFRYSGRT QTRQ+S ++DRP P+FER+ R+S
Sbjct: 1140MFPRLGSKFRYSGRTLYQTRQSSQILDRPNPYFERSQPARSS 1265
Score = 41.6 bits (96), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 21/55 (38%), Positives = 33/55 (60%), Gaps = 2/55 (3%)
Frame = +3
Query: 719 KGGISETRIEKRIVITG--DADIDHDQVLVQAIKEAKEQHPDMSVTKVVVHQETE 771
K GI TR+E ++V++ D + D+D L AI+ E +PDMSV ++ Q+ E
Sbjct: 2145 KDGIQHTRVEHKVVLSSADDEEFDYDAALADAIRSVTEFNPDMSVERIECVQQIE 2309
>18811
Length = 478
Score = 187 bits (475), Expect = 1e-47, Method: Compositional matrix adjust.
Identities = 79/134 (58%), Positives = 108/134 (80%)
Frame = -2
Query: 310 HGVDYVSDFKLAPNQTKELEEKVMELHKSYRSMTPAQADLEFLENAKKLSMYGVDLHKAK 369
HG DY+ D APNQ EL EK++ELH+ ++ TP +A++ +LENAKKLSMYGVDLH A+
Sbjct: 402 HGADYIKDIPFAPNQAPELLEKIVELHRQHKGQTPDEAEVNYLENAKKLSMYGVDLHAAQ 223
Query: 370 DLEGVDIILGVCSSGLLVYKDKLRINRFPWPKVLKISYKRSSFFIKIRPGEQEQYESTIG 429
D+ VDI+LGVCSSGL VY+DKLRI+RF WPK++KISYKR F++K+RP + + E+++
Sbjct: 222 DVNNVDIMLGVCSSGLQVYRDKLRISRFVWPKIIKISYKRKHFYVKVRPADNKGLETSVS 43
Query: 430 FKLPSYRAAKKLWK 443
F+LP++R AK+LWK
Sbjct: 42 FRLPTHRLAKRLWK 1
>11374
Length = 800
Score = 177 bits (449), Expect = 1e-44, Method: Compositional matrix adjust.
Identities = 80/140 (57%), Positives = 104/140 (74%), Gaps = 1/140 (0%)
Frame = +3
Query: 365 LHKAKDLEGVDIILGVCSSGLLVYKDKLRINRFPWPKVLKISYKRSSFFIKIRPGEQEQY 424
LH A+D+ VDI+LGVC+SGL VY++KLRI+RF WPK+LKISYKR F+IK+RP +
Sbjct: 3 LHAAQDVNNVDIMLGVCASGLQVYREKLRISRFVWPKILKISYKRRQFYIKVRPSDNSAM 182
Query: 425 ESTIGFKLPSYRAAKKLWKVCVEHHTFFRLTSTD-TIPKSKFLALGSKFRYSGRTQAQTR 483
E++ FKL ++R AK+LWK+CVEHH FFRL + + + F LGSKFRYSGRT QTR
Sbjct: 183 ENSFCFKLATHRLAKRLWKICVEHHAFFRLREAEQSQNAAMFPRLGSKFRYSGRTLYQTR 362
Query: 484 QASALIDRPAPHFERTASKR 503
+S +DRP P+FER+ R
Sbjct: 363 HSSQTLDRPDPYFERSQPAR 422
>17332
Length = 473
Score = 115 bits (288), Expect = 6e-26, Method: Compositional matrix adjust.
Identities = 55/111 (49%), Positives = 72/111 (64%), Gaps = 2/111 (1%)
Frame = +2
Query: 229 WLDSAKEIKKQVRGV--PWNFTFNVKFYPPDPAQLTEDITRYYLCLQLRQDIVAGRLPCS 286
WLD K + Q++G P F VKFY DP +L E+ITRY LQ++QDI+ GRLP +
Sbjct: 140 WLDGNKSLSSQLKGCQTPHKLYFGVKFYAADPCKLREEITRYLFFLQVKQDILQGRLPVT 319
Query: 287 FATLALLGSYTIQSELGDYDPELHGVDYVSDFKLAPNQTKELEEKVMELHK 337
F + L +Y +QSELGD+DP H YVS+F PNQT+ELE +V LH+
Sbjct: 320 FDEASELCAYAVQSELGDFDPRQHTDGYVSEFCFIPNQTEELERRVAGLHR 472
>28244
Length = 422
Score = 79.0 bits (193), Expect = 7e-15, Method: Composition-based stats.
Identities = 47/124 (37%), Positives = 67/124 (54%), Gaps = 4/124 (3%)
Frame = -1
Query: 386 LVYKDKLRINRFPWPKVLKISYKRSSF-FIKIRPGEQEQYESTIG-FKLPSYRAAKKLWK 443
LV++ +I F WPK+ ++ +K + + E Q + I F+L S +A K LWK
Sbjct: 422 LVFEGNXKIGLFFWPKMTRLDFKGKKLTLVAVEDDENGQSQDHIFVFRLQSEKACKHLWK 243
Query: 444 VCVEHHTFFRLTSTDTIPKSK--FLALGSKFRYSGRTQAQTRQASALIDRPAPHFERTAS 501
VEHH FFRL P ++ F +GS+FRYSGRT+ QT + R + FER S
Sbjct: 242 CAVEHHAFFRLKGPVQGPNARQNFFRMGSRFRYSGRTEYQTSTMNRA--RRSVKFERKPS 69
Query: 502 KRAS 505
+R S
Sbjct: 68 QRYS 57
>08363
Length = 1878
Score = 67.8 bits (164), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 45/126 (35%), Positives = 67/126 (53%), Gaps = 1/126 (0%)
Frame = +1
Query: 640 PPLVKTQTVTISDNANAVKSEIPTKDVPIVHTETKTITYEAAQTDDNSGDLDPGVLLTAX 699
PP V T++V + V +PTK+VP+V TET+T+TYE + D + GVL++A
Sbjct: 115 PPTVATESVHYQPDVEEVP--VPTKNVPLVKTETRTVTYER---EGFPFDGEDGVLVSAS 279
Query: 700 XXXXXXXXXXXXXXXXXXVKGGISETRIEKRIVITG-DADIDHDQVLVQAIKEAKEQHPD 758
K G+ ETR+E R+V++ D D D+D L AI+ E +PD
Sbjct: 280 SHSTRMQTIETTTYKTE--KDGVQETRVEHRVVLSSTDDDFDYDAALADAIRSVTEFNPD 453
Query: 759 MSVTKV 764
MSV ++
Sbjct: 454 MSVERI 471
>03469
Length = 1275
Score = 65.5 bits (158), Expect = 7e-11, Method: Compositional matrix adjust.
Identities = 43/116 (37%), Positives = 63/116 (54%), Gaps = 2/116 (1%)
Frame = -3
Query: 661 IPTKDVPIVHTETKTITYEAAQTDDNSGDLDPGVLLTAXXXXXXXXXXXXXXXXXXXVKG 720
+PTK+VP+V TET+T+TYE + D + GVL++A K
Sbjct: 1258 VPTKNVPLVKTETRTVTYER---EGFPFDGEDGVLVSASSHSTRMQTIETTTYKTE--KD 1094
Query: 721 GISETRIEKRIVITG-DADIDHDQVLVQAIKEAKEQHPDMSVTKV-VVHQETEIAD 774
G+ ETR+E R+V++ D D D+D L AI+ E +PDMSV ++ V Q E+ D
Sbjct: 1093 GVQETRVEHRVVLSSTDDDFDYDAALADAIRSVTEFNPDMSVERIECVQQIEEVKD 926
>13951
Length = 720
Score = 51.6 bits (122), Expect = 1e-06, Method: Composition-based stats.
Identities = 23/50 (46%), Positives = 31/50 (62%)
Frame = -1
Query: 234 KEIKKQVRGVPWNFTFNVKFYPPDPAQLTEDITRYYLCLQLRQDIVAGRL 283
K+ + + +G PW F F +KFYPPDP QL E +TR+ + L VAG L
Sbjct: 204 KDFQNRKKGGPWLFDFALKFYPPDPTQLRESLTRWLVVLH-----VAGEL 70
>05888
Length = 490
Score = 49.3 bits (116), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 22/36 (61%), Positives = 26/36 (72%)
Frame = -2
Query: 468 LGSKFRYSGRTQAQTRQASALIDRPAPHFERTASKR 503
LGSKFRYSGRT Q R +S +DRP P+FER+ R
Sbjct: 489 LGSKFRYSGRTLYQARHSSQTLDRPDPYFERSQPAR 382
>12829
Length = 2357
Score = 31.6 bits (70), Expect = 1.2, Method: Compositional matrix adjust.
Identities = 14/40 (35%), Positives = 24/40 (60%)
Frame = -2
Query: 124 EEIILKAPIAAPEPELKTDPSLDLHSLSSAETQPAQEELR 163
EEI+L +P+A+P+P+ PS+ + + S Q A+ R
Sbjct: 1669 EEIVLVSPLASPQPDFPMSPSVSVLGVPSPRIQTARSPSR 1550
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000381828 | hsapiens_gene_ensembl | Protein 4.1
(Band 4.1) (P4.1) (EPB4.1) (4.1R).
[Source:Uniprot/SWISSPROT;Acc:P11171]
(552 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
00990 345 3e-95
18811 186 2e-47
11374 176 2e-44
17332 116 2e-26
28244 79 4e-15
08363 68 1e-11
03469 65 6e-11
05888 49 6e-06
13951 48 9e-06
17496 31 1.4
>00990
Length = 3161
Score = 345 bits (885), Expect = 3e-95, Method: Compositional matrix adjust.
Identities = 158/282 (56%), Positives = 212/282 (75%), Gaps = 2/282 (0%)
Frame = +3
Query: 3 LETWLDSAKEIKKQVRGVPWNFTFNVKFYPPDPAQLTEDITRYYLCLQLRQDIVAGRLPC 62
L+ WL K I KQ +G PW F F +KFYPPDP QL E +TR+ + LQ R+DI++G+LP
Sbjct: 420 LKCWLSPDKRISKQKKGGPWLFDFALKFYPPDPTQLRESLTRWLVVLQTRRDILSGKLPA 599
Query: 63 SFATLALLGSYTIQSELGDYDPELH-GVDYVSDFKLAPNQTKELEEKVMELHKSYRSMTP 121
++ T A+LGSY +Q+++GDYDP H GV+Y+ D APNQT +L EK++ELH+ ++ TP
Sbjct: 600 TYLTQAMLGSYCVQADVGDYDPNEHRGVEYIRDTPFAPNQTIDLLEKIVELHRQHKGQTP 779
Query: 122 AQADLEFLENAKKLSMYGVDLHKAKDLEGVDIILGVCSSGLLVYKDKLRINRFPWPKVLK 181
+A+ FLENAKKL+MYGVDLH A+D+ VDI+LGVC+SGL VY++KLRI+RF WPK+LK
Sbjct: 780 DEAETNFLENAKKLAMYGVDLHAAQDVNNVDIMLGVCASGLQVYREKLRISRFVWPKILK 959
Query: 182 ISYKRSSFFIKIRPGEQEQYESTIGFKLPSYRAAKKLWKVCVEHHTFFRLTSTD-TIPKS 240
ISYKR F+IK+RP + E++ FKL ++R AK+LWK+CVEHH FFRL + + +
Sbjct: 960 ISYKRRQFYIKVRPSDNSAMENSFCFKLATHRLAKRLWKICVEHHAFFRLREAEQSQNAA 1139
Query: 241 KFLALGSKFRYSGRTQAQTRQASALIDRPAPHFERTASKRAS 282
F LGSKFRYSGRT QTRQ+S ++DRP P+FER+ R+S
Sbjct: 1140MFPRLGSKFRYSGRTLYQTRQSSQILDRPNPYFERSQPARSS 1265
Score = 42.0 bits (97), Expect = 6e-04, Method: Compositional matrix adjust.
Identities = 21/55 (38%), Positives = 33/55 (60%), Gaps = 2/55 (3%)
Frame = +3
Query: 496 KGGISETRIEKRIVITG--DADIDHDQVLVQAIKEAKEQHPDMSVTKVVVHQETE 548
K GI TR+E ++V++ D + D+D L AI+ E +PDMSV ++ Q+ E
Sbjct: 2145 KDGIQHTRVEHKVVLSSADDEEFDYDAALADAIRSVTEFNPDMSVERIECVQQIE 2309
>18811
Length = 478
Score = 186 bits (473), Expect = 2e-47, Method: Compositional matrix adjust.
Identities = 79/134 (58%), Positives = 108/134 (80%)
Frame = -2
Query: 87 HGVDYVSDFKLAPNQTKELEEKVMELHKSYRSMTPAQADLEFLENAKKLSMYGVDLHKAK 146
HG DY+ D APNQ EL EK++ELH+ ++ TP +A++ +LENAKKLSMYGVDLH A+
Sbjct: 402 HGADYIKDIPFAPNQAPELLEKIVELHRQHKGQTPDEAEVNYLENAKKLSMYGVDLHAAQ 223
Query: 147 DLEGVDIILGVCSSGLLVYKDKLRINRFPWPKVLKISYKRSSFFIKIRPGEQEQYESTIG 206
D+ VDI+LGVCSSGL VY+DKLRI+RF WPK++KISYKR F++K+RP + + E+++
Sbjct: 222 DVNNVDIMLGVCSSGLQVYRDKLRISRFVWPKIIKISYKRKHFYVKVRPADNKGLETSVS 43
Query: 207 FKLPSYRAAKKLWK 220
F+LP++R AK+LWK
Sbjct: 42 FRLPTHRLAKRLWK 1
>11374
Length = 800
Score = 176 bits (446), Expect = 2e-44, Method: Compositional matrix adjust.
Identities = 80/140 (57%), Positives = 104/140 (74%), Gaps = 1/140 (0%)
Frame = +3
Query: 142 LHKAKDLEGVDIILGVCSSGLLVYKDKLRINRFPWPKVLKISYKRSSFFIKIRPGEQEQY 201
LH A+D+ VDI+LGVC+SGL VY++KLRI+RF WPK+LKISYKR F+IK+RP +
Sbjct: 3 LHAAQDVNNVDIMLGVCASGLQVYREKLRISRFVWPKILKISYKRRQFYIKVRPSDNSAM 182
Query: 202 ESTIGFKLPSYRAAKKLWKVCVEHHTFFRLTSTD-TIPKSKFLALGSKFRYSGRTQAQTR 260
E++ FKL ++R AK+LWK+CVEHH FFRL + + + F LGSKFRYSGRT QTR
Sbjct: 183 ENSFCFKLATHRLAKRLWKICVEHHAFFRLREAEQSQNAAMFPRLGSKFRYSGRTLYQTR 362
Query: 261 QASALIDRPAPHFERTASKR 280
+S +DRP P+FER+ R
Sbjct: 363 HSSQTLDRPDPYFERSQPAR 422
>17332
Length = 473
Score = 116 bits (291), Expect = 2e-26, Method: Composition-based stats.
Identities = 55/111 (49%), Positives = 72/111 (64%), Gaps = 2/111 (1%)
Frame = +2
Query: 6 WLDSAKEIKKQVRG--VPWNFTFNVKFYPPDPAQLTEDITRYYLCLQLRQDIVAGRLPCS 63
WLD K + Q++G P F VKFY DP +L E+ITRY LQ++QDI+ GRLP +
Sbjct: 140 WLDGNKSLSSQLKGCQTPHKLYFGVKFYAADPCKLREEITRYLFFLQVKQDILQGRLPVT 319
Query: 64 FATLALLGSYTIQSELGDYDPELHGVDYVSDFKLAPNQTKELEEKVMELHK 114
F + L +Y +QSELGD+DP H YVS+F PNQT+ELE +V LH+
Sbjct: 320 FDEASELCAYAVQSELGDFDPRQHTDGYVSEFCFIPNQTEELERRVAGLHR 472
>28244
Length = 422
Score = 79.3 bits (194), Expect = 4e-15, Method: Composition-based stats.
Identities = 47/124 (37%), Positives = 67/124 (54%), Gaps = 4/124 (3%)
Frame = -1
Query: 163 LVYKDKLRINRFPWPKVLKISYKRSSF-FIKIRPGEQEQYESTIG-FKLPSYRAAKKLWK 220
LV++ +I F WPK+ ++ +K + + E Q + I F+L S +A K LWK
Sbjct: 422 LVFEGNXKIGLFFWPKMTRLDFKGKKLTLVAVEDDENGQSQDHIFVFRLQSEKACKHLWK 243
Query: 221 VCVEHHTFFRLTSTDTIPKSK--FLALGSKFRYSGRTQAQTRQASALIDRPAPHFERTAS 278
VEHH FFRL P ++ F +GS+FRYSGRT+ QT + R + FER S
Sbjct: 242 CAVEHHAFFRLKGPVQGPNARQNFFRMGSRFRYSGRTEYQTSTMNRA--RRSVKFERKPS 69
Query: 279 KRAS 282
+R S
Sbjct: 68 QRYS 57
>08363
Length = 1878
Score = 67.8 bits (164), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 47/133 (35%), Positives = 69/133 (51%), Gaps = 1/133 (0%)
Frame = +1
Query: 417 PPLVKTQTVTISDNANAVKSEIPTKDVPIVHTETKTITYEAAQTDDNSGDLDPGVLLTAX 476
PP V T++V + V +PTK+VP+V TET+T+TYE + D + GVL++A
Sbjct: 115 PPTVATESVHYQPDVEEVP--VPTKNVPLVKTETRTVTYER---EGFPFDGEDGVLVSAS 279
Query: 477 XXXXXXXXXXXXXXXXXXVKGGISETRIEKRIVITG-DADIDHDQVLVQAIKEAKEQHPD 535
K G+ ETR+E R+V++ D D D+D L AI+ E +PD
Sbjct: 280 SHSTRMQTIETTTYKTE--KDGVQETRVEHRVVLSSTDDDFDYDAALADAIRSVTEFNPD 453
Query: 536 MSVTKVVVHQETE 548
MSV ++ Q E
Sbjct: 454 MSVERIECVQXIE 492
>03469
Length = 1275
Score = 65.5 bits (158), Expect = 6e-11, Method: Compositional matrix adjust.
Identities = 43/116 (37%), Positives = 63/116 (54%), Gaps = 2/116 (1%)
Frame = -3
Query: 438 IPTKDVPIVHTETKTITYEAAQTDDNSGDLDPGVLLTAXXXXXXXXXXXXXXXXXXXVKG 497
+PTK+VP+V TET+T+TYE + D + GVL++A K
Sbjct: 1258 VPTKNVPLVKTETRTVTYER---EGFPFDGEDGVLVSASSHSTRMQTIETTTYKTE--KD 1094
Query: 498 GISETRIEKRIVITG-DADIDHDQVLVQAIKEAKEQHPDMSVTKV-VVHQETEIAD 551
G+ ETR+E R+V++ D D D+D L AI+ E +PDMSV ++ V Q E+ D
Sbjct: 1093 GVQETRVEHRVVLSSTDDDFDYDAALADAIRSVTEFNPDMSVERIECVQQIEEVKD 926
>05888
Length = 490
Score = 48.9 bits (115), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 22/36 (61%), Positives = 26/36 (72%)
Frame = -2
Query: 245 LGSKFRYSGRTQAQTRQASALIDRPAPHFERTASKR 280
LGSKFRYSGRT Q R +S +DRP P+FER+ R
Sbjct: 489 LGSKFRYSGRTLYQARHSSQTLDRPDPYFERSQPAR 382
>13951
Length = 720
Score = 48.1 bits (113), Expect = 9e-06, Method: Compositional matrix adjust.
Identities = 23/50 (46%), Positives = 31/50 (62%)
Frame = -1
Query: 11 KEIKKQVRGVPWNFTFNVKFYPPDPAQLTEDITRYYLCLQLRQDIVAGRL 60
K+ + + +G PW F F +KFYPPDP QL E +TR+ + L VAG L
Sbjct: 204 KDFQNRKKGGPWLFDFALKFYPPDPTQLRESLTRWLVVLH-----VAGEL 70
>17496
Length = 461
Score = 30.8 bits (68), Expect = 1.4, Method: Compositional matrix adjust.
Identities = 15/38 (39%), Positives = 23/38 (60%), Gaps = 2/38 (5%)
Frame = +3
Query: 141 DLHKAKDLEGVDIILGVCSSGLL--VYKDKLRINRFPW 176
DLH+A+ +GV ++L SGL +K K +R+PW
Sbjct: 111 DLHRARTFQGVTLLLWETLSGLQKPGWKGKELKSRWPW 224
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000381837 | hsapiens_gene_ensembl | Protein 4.1
(Band 4.1) (P4.1) (EPB4.1) (4.1R).
[Source:Uniprot/SWISSPROT;Acc:P11171]
(704 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
00990 345 3e-95
18811 187 1e-47
11374 177 1e-44
17332 115 4e-26
28244 79 5e-15
08363 68 1e-11
03469 66 6e-11
05888 49 6e-06
13951 48 1e-05
12829 32 0.82
17496 31 1.9
>00990
Length = 3161
Score = 345 bits (886), Expect = 3e-95, Method: Compositional matrix adjust.
Identities = 158/285 (55%), Positives = 212/285 (74%), Gaps = 2/285 (0%)
Frame = +3
Query: 152 SAETQTWLDSAKEIKKQVRGVPWNFTFNVKFYPPDPAQLTEDITRYYLCLQLRQDIVAGR 211
S + WL K I KQ +G PW F F +KFYPPDP QL E +TR+ + LQ R+DI++G+
Sbjct: 411 SNHLKCWLSPDKRISKQKKGGPWLFDFALKFYPPDPTQLRESLTRWLVVLQTRRDILSGK 590
Query: 212 LPCSFATLALLGSYTIQSELGDYDPELH-GVDYVSDFKLAPNQTKELEEKVMELHKSYRS 270
LP ++ T A+LGSY +Q+++GDYDP H GV+Y+ D APNQT +L EK++ELH+ ++
Sbjct: 591 LPATYLTQAMLGSYCVQADVGDYDPNEHRGVEYIRDTPFAPNQTIDLLEKIVELHRQHKG 770
Query: 271 MTPAQADLEFLENAKKLSMYGVDLHKAKDLEGVDIILGVCSSGLLVYKDKLRINRFPWPK 330
TP +A+ FLENAKKL+MYGVDLH A+D+ VDI+LGVC+SGL VY++KLRI+RF WPK
Sbjct: 771 QTPDEAETNFLENAKKLAMYGVDLHAAQDVNNVDIMLGVCASGLQVYREKLRISRFVWPK 950
Query: 331 VLKISYKRSSFFIKIRPGEQEQYESTIGFKLPSYRAAKKLWKVCVEHHTFFRLTSTD-TI 389
+LKISYKR F+IK+RP + E++ FKL ++R AK+LWK+CVEHH FFRL + +
Sbjct: 951 ILKISYKRRQFYIKVRPSDNSAMENSFCFKLATHRLAKRLWKICVEHHAFFRLREAEQSQ 1130
Query: 390 PKSKFLALGSKFRYSGRTQAQTRQASALIDRPAPHFERTASKRAS 434
+ F LGSKFRYSGRT QTRQ+S ++DRP P+FER+ R+S
Sbjct: 1131NAAMFPRLGSKFRYSGRTLYQTRQSSQILDRPNPYFERSQPARSS 1265
Score = 42.0 bits (97), Expect = 8e-04, Method: Compositional matrix adjust.
Identities = 21/55 (38%), Positives = 33/55 (60%), Gaps = 2/55 (3%)
Frame = +3
Query: 648 KGGISETRIEKRIVITG--DADIDHDQVLVQAIKEAKEQHPDMSVTKVVVHQETE 700
K GI TR+E ++V++ D + D+D L AI+ E +PDMSV ++ Q+ E
Sbjct: 2145 KDGIQHTRVEHKVVLSSADDEEFDYDAALADAIRSVTEFNPDMSVERIECVQQIE 2309
>18811
Length = 478
Score = 187 bits (475), Expect = 1e-47, Method: Compositional matrix adjust.
Identities = 79/134 (58%), Positives = 108/134 (80%)
Frame = -2
Query: 239 HGVDYVSDFKLAPNQTKELEEKVMELHKSYRSMTPAQADLEFLENAKKLSMYGVDLHKAK 298
HG DY+ D APNQ EL EK++ELH+ ++ TP +A++ +LENAKKLSMYGVDLH A+
Sbjct: 402 HGADYIKDIPFAPNQAPELLEKIVELHRQHKGQTPDEAEVNYLENAKKLSMYGVDLHAAQ 223
Query: 299 DLEGVDIILGVCSSGLLVYKDKLRINRFPWPKVLKISYKRSSFFIKIRPGEQEQYESTIG 358
D+ VDI+LGVCSSGL VY+DKLRI+RF WPK++KISYKR F++K+RP + + E+++
Sbjct: 222 DVNNVDIMLGVCSSGLQVYRDKLRISRFVWPKIIKISYKRKHFYVKVRPADNKGLETSVS 43
Query: 359 FKLPSYRAAKKLWK 372
F+LP++R AK+LWK
Sbjct: 42 FRLPTHRLAKRLWK 1
>11374
Length = 800
Score = 177 bits (450), Expect = 1e-44, Method: Compositional matrix adjust.
Identities = 80/140 (57%), Positives = 104/140 (74%), Gaps = 1/140 (0%)
Frame = +3
Query: 294 LHKAKDLEGVDIILGVCSSGLLVYKDKLRINRFPWPKVLKISYKRSSFFIKIRPGEQEQY 353
LH A+D+ VDI+LGVC+SGL VY++KLRI+RF WPK+LKISYKR F+IK+RP +
Sbjct: 3 LHAAQDVNNVDIMLGVCASGLQVYREKLRISRFVWPKILKISYKRRQFYIKVRPSDNSAM 182
Query: 354 ESTIGFKLPSYRAAKKLWKVCVEHHTFFRLTSTD-TIPKSKFLALGSKFRYSGRTQAQTR 412
E++ FKL ++R AK+LWK+CVEHH FFRL + + + F LGSKFRYSGRT QTR
Sbjct: 183 ENSFCFKLATHRLAKRLWKICVEHHAFFRLREAEQSQNAAMFPRLGSKFRYSGRTLYQTR 362
Query: 413 QASALIDRPAPHFERTASKR 432
+S +DRP P+FER+ R
Sbjct: 363 HSSQTLDRPDPYFERSQPAR 422
>17332
Length = 473
Score = 115 bits (289), Expect = 4e-26, Method: Composition-based stats.
Identities = 58/117 (49%), Positives = 75/117 (64%), Gaps = 3/117 (2%)
Frame = +2
Query: 153 AETQT-WLDSAKEIKKQVRG--VPWNFTFNVKFYPPDPAQLTEDITRYYLCLQLRQDIVA 209
A QT WLD K + Q++G P F VKFY DP +L E+ITRY LQ++QDI+
Sbjct: 122 ASGQTHWLDGNKSLSSQLKGCQTPHKLYFGVKFYAADPCKLREEITRYLFFLQVKQDILQ 301
Query: 210 GRLPCSFATLALLGSYTIQSELGDYDPELHGVDYVSDFKLAPNQTKELEEKVMELHK 266
GRLP +F + L +Y +QSELGD+DP H YVS+F PNQT+ELE +V LH+
Sbjct: 302 GRLPVTFDEASELCAYAVQSELGDFDPRQHTDGYVSEFCFIPNQTEELERRVAGLHR 472
>28244
Length = 422
Score = 79.3 bits (194), Expect = 5e-15, Method: Composition-based stats.
Identities = 47/124 (37%), Positives = 67/124 (54%), Gaps = 4/124 (3%)
Frame = -1
Query: 315 LVYKDKLRINRFPWPKVLKISYKRSSF-FIKIRPGEQEQYESTIG-FKLPSYRAAKKLWK 372
LV++ +I F WPK+ ++ +K + + E Q + I F+L S +A K LWK
Sbjct: 422 LVFEGNXKIGLFFWPKMTRLDFKGKKLTLVAVEDDENGQSQDHIFVFRLQSEKACKHLWK 243
Query: 373 VCVEHHTFFRLTSTDTIPKSK--FLALGSKFRYSGRTQAQTRQASALIDRPAPHFERTAS 430
VEHH FFRL P ++ F +GS+FRYSGRT+ QT + R + FER S
Sbjct: 242 CAVEHHAFFRLKGPVQGPNARQNFFRMGSRFRYSGRTEYQTSTMNRA--RRSVKFERKPS 69
Query: 431 KRAS 434
+R S
Sbjct: 68 QRYS 57
>08363
Length = 1878
Score = 68.2 bits (165), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 47/133 (35%), Positives = 69/133 (51%), Gaps = 1/133 (0%)
Frame = +1
Query: 569 PPLVKTQTVTISDNANAVKSEIPTKDVPIVHTETKTITYEAAQTDDNSGDLDPGVLLTAX 628
PP V T++V + V +PTK+VP+V TET+T+TYE + D + GVL++A
Sbjct: 115 PPTVATESVHYQPDVEEVP--VPTKNVPLVKTETRTVTYER---EGFPFDGEDGVLVSAS 279
Query: 629 XXXXXXXXXXXXXXXXXXVKGGISETRIEKRIVITG-DADIDHDQVLVQAIKEAKEQHPD 687
K G+ ETR+E R+V++ D D D+D L AI+ E +PD
Sbjct: 280 SHSTRMQTIETTTYKTE--KDGVQETRVEHRVVLSSTDDDFDYDAALADAIRSVTEFNPD 453
Query: 688 MSVTKVVVHQETE 700
MSV ++ Q E
Sbjct: 454 MSVERIECVQXIE 492
>03469
Length = 1275
Score = 65.9 bits (159), Expect = 6e-11, Method: Compositional matrix adjust.
Identities = 43/116 (37%), Positives = 63/116 (54%), Gaps = 2/116 (1%)
Frame = -3
Query: 590 IPTKDVPIVHTETKTITYEAAQTDDNSGDLDPGVLLTAXXXXXXXXXXXXXXXXXXXVKG 649
+PTK+VP+V TET+T+TYE + D + GVL++A K
Sbjct: 1258 VPTKNVPLVKTETRTVTYER---EGFPFDGEDGVLVSASSHSTRMQTIETTTYKTE--KD 1094
Query: 650 GISETRIEKRIVITG-DADIDHDQVLVQAIKEAKEQHPDMSVTKV-VVHQETEIAD 703
G+ ETR+E R+V++ D D D+D L AI+ E +PDMSV ++ V Q E+ D
Sbjct: 1093 GVQETRVEHRVVLSSTDDDFDYDAALADAIRSVTEFNPDMSVERIECVQQIEEVKD 926
>05888
Length = 490
Score = 49.3 bits (116), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 22/36 (61%), Positives = 26/36 (72%)
Frame = -2
Query: 397 LGSKFRYSGRTQAQTRQASALIDRPAPHFERTASKR 432
LGSKFRYSGRT Q R +S +DRP P+FER+ R
Sbjct: 489 LGSKFRYSGRTLYQARHSSQTLDRPDPYFERSQPAR 382
>13951
Length = 720
Score = 48.1 bits (113), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 23/50 (46%), Positives = 31/50 (62%)
Frame = -1
Query: 163 KEIKKQVRGVPWNFTFNVKFYPPDPAQLTEDITRYYLCLQLRQDIVAGRL 212
K+ + + +G PW F F +KFYPPDP QL E +TR+ + L VAG L
Sbjct: 204 KDFQNRKKGGPWLFDFALKFYPPDPTQLRESLTRWLVVLH-----VAGEL 70
>12829
Length = 2357
Score = 32.0 bits (71), Expect = 0.82, Method: Compositional matrix adjust.
Identities = 13/34 (38%), Positives = 22/34 (64%)
Frame = -2
Query: 124 EEIILKAPIAAPEPELKTDPSLDLHSLSSAETQT 157
EEI+L +P+A+P+P+ PS+ + + S QT
Sbjct: 1669 EEIVLVSPLASPQPDFPMSPSVSVLGVPSPRIQT 1568
>17496
Length = 461
Score = 30.8 bits (68), Expect = 1.9, Method: Compositional matrix adjust.
Identities = 15/38 (39%), Positives = 23/38 (60%), Gaps = 2/38 (5%)
Frame = +3
Query: 293 DLHKAKDLEGVDIILGVCSSGLL--VYKDKLRINRFPW 328
DLH+A+ +GV ++L SGL +K K +R+PW
Sbjct: 111 DLHRARTFQGVTLLLWETLSGLQKPGWKGKELKSRWPW 224
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000228307 | hsapiens_gene_ensembl | Paxillin.
[Source:Uniprot/SWISSPROT;Acc:P49023]
(591 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
11928 340 1e-93
09680 129 3e-30
07437 126 2e-29
14307 87 2e-17
05726 74 2e-13
34420 44 2e-04
26762 43 3e-04
05103 40 0.003
30169 35 0.087
15283 30 1.9
02288 29 4.4
17933 29 6.2
04349 28 7.0
12399 27 9.9
>11928
Length = 1623
Score = 340 bits (871), Expect = 1e-93, Method: Compositional matrix adjust.
Identities = 152/221 (68%), Positives = 176/221 (79%)
Frame = -2
Query: 350 VATVAKGVCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDY 409
V T KGVC AC KPI GQV+ A+G+TWH EHFVC HC++ +G+ NF+ERD YCE DY
Sbjct: 1622 VNTKKKGVCAACNKPIVGQVIAALGRTWHVEHFVCAHCEQPLGTSNFYERDSVAYCEVDY 1443
Query: 410 HNLFSPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYF 469
HNLF+PRC YCNGPI+DK +TAL++ WHPEHFFCAQCG FG E FHEK+GKAYCR DYF
Sbjct: 1442 HNLFAPRCAYCNGPIVDKCITALEKMWHPEHFFCAQCGRQFGDEDFHEKNGKAYCRDDYF 1263
Query: 470 DMFAPKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHE 529
MFAPKCGGC I+ENYISALN WHP+CF C EC PF GSF++HDG PYCE HYH
Sbjct: 1262 QMFAPKCGGCGMPIMENYISALNRQWHPQCFCCWECQAPFGTGSFYDHDGLPYCETHYHA 1083
Query: 530 RRGSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNK 570
++GSLC+ CQKPITGRCITAM KKFHPEH FCL+ L++
Sbjct: 1082 KKGSLCASCQKPITGRCITAMFKKFHPEH----FCLRLLHQ 972
Score = 140 bits (353), Expect = 1e-33, Method: Compositional matrix adjust.
Identities = 67/168 (39%), Positives = 94/168 (55%)
Frame = -2
Query: 417 CYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKC 476
C CN PI+ +V+ AL RTWH EHF CA C G F+E+D AYC DY ++FAP+C
Sbjct: 1598 CAACNKPIVGQVIAALGRTWHVEHFVCAHCEQPLGTSNFYERDSVAYCEVDYHNLFAPRC 1419
Query: 477 GGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCS 536
C I++ I+AL +WHPE F C +C F + F E +G+ YC Y + C
Sbjct: 1418 AYCNGPIVDKCITALEKMWHPEHFFCAQCGRQFGDEDFHEKNGKAYCRDDYFQMFAPKCG 1239
Query: 537 GCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQN 584
GC PI I+A+ +++HP+ F C C G+F + + PYC+
Sbjct: 1238 GCGMPIMENYISALNRQWHPQCFCCWECQAPFGTGSFYDHDGLPYCET 1095
Score = 102 bits (253), Expect = 6e-22, Method: Compositional matrix adjust.
Identities = 48/115 (41%), Positives = 64/115 (55%)
Frame = -2
Query: 476 CGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLC 535
C C + I+ I+AL WH E FVC C P +F+E D YCEV YH C
Sbjct: 1598 CAACNKPIVGQVIAALGRTWHVEHFVCAHCEQPLGTSNFYERDSVAYCEVDYHNLFAPRC 1419
Query: 536 SGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 590
+ C PI +CITA+ K +HPEHF CA C +Q F E+N K YC++ + ++F
Sbjct: 1418 AYCNGPIVDKCITALEKMWHPEHFFCAQCGRQFGDEDFHEKNGKAYCRDDYFQMF 1254
Score = 69.7 bits (169), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 29/40 (72%), Positives = 33/40 (82%)
Frame = -3
Query: 551 AKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 590
++ F FVCAFC+KQLNKGTFKEQNDKPYC CF+KLF
Sbjct: 1018 SRSFTRSIFVCAFCIKQLNKGTFKEQNDKPYCHPCFVKLF 899
Score = 53.1 bits (126), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 23/61 (37%), Positives = 36/61 (59%)
Frame = -2
Query: 530 RRGSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKL 589
++ +C+ C KPI G+ I A+ + +H EHFVCA C + L F E++ YC+ + L
Sbjct: 1613 KKKGVCAACNKPIVGQVIAALGRTWHVEHFVCAHCEQPLGTSNFYERDSVAYCEVDYHNL 1434
Query: 590 F 590
F
Sbjct: 1433 F 1431
Score = 30.0 bits (66), Expect = 2.5, Method: Compositional matrix adjust.
Identities = 11/32 (34%), Positives = 18/32 (56%)
Frame = -3
Query: 382 FVCTHCQEEIGSRNFFERDGQPYCEKDYHNLF 413
FVC C +++ F E++ +PYC + LF
Sbjct: 994 FVCAFCIKQLNKGTFKEQNDKPYCHPCFVKLF 899
>09680
Length = 878
Score = 129 bits (325), Expect = 3e-30, Method: Compositional matrix adjust.
Identities = 65/177 (36%), Positives = 91/177 (51%), Gaps = 3/177 (1%)
Frame = -2
Query: 350 VATVAKGV--CGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEK 407
+A +AK C C + I +VV A+GK +HPEHF+C C ++I F + G+P C
Sbjct: 745 IALIAKQQYQCHKCNEAITSRVVFALGKNYHPEHFLCRDCDKQIKDDIFNIQQGEPVCNA 566
Query: 408 DYHNLFSPRCYYCNGPILDKVVTALDRTWHPEHFFC-AQCGAFFGPEGFHEKDGKAYCRK 466
Y ++ C C PI ++A+ WH F C C F E++GKAYCR+
Sbjct: 565 CYLERYTSTCAGCKEPIHGTTISAMGNNWHEHCFVCDGACKQPLKDSSFFEREGKAYCRQ 386
Query: 467 DYFDMFAPKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYC 523
DY D+FA +C C + I EN I A+N WH +CF C C P +F +P C
Sbjct: 385 DYEDLFAVRCAKCEKPITENAIVAMNAKWHSDCFCCNRCDNPIKTKTFTIEGDKPIC 215
Score = 120 bits (301), Expect = 1e-27, Method: Compositional matrix adjust.
Identities = 63/171 (36%), Positives = 85/171 (49%), Gaps = 1/171 (0%)
Frame = -2
Query: 416 RCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPK 475
+C+ CN I +VV AL + +HPEHF C C + F+ + G+ C Y + +
Sbjct: 718 QCHKCNEAITSRVVFALGKNYHPEHFLCRDCDKQIKDDIFNIQQGEPVCNACYLERYTST 539
Query: 476 CGGCARAILENYISALNTLWHPECFVCR-ECFTPFVNGSFFEHDGQPYCEVHYHERRGSL 534
C GC I ISA+ WH CFVC C P + SFFE +G+ YC Y +
Sbjct: 538 CAGCKEPIHGTTISAMGNNWHEHCFVCDGACKQPLKDSSFFEREGKAYCRQDYEDLFAVR 359
Query: 535 CSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNC 585
C+ C+KPIT I AM K+H + F C C + TF + DKP C C
Sbjct: 358 CAKCEKPITENAIVAMNAKWHSDCFCCNRCDNPIKTKTFTIEGDKPICPAC 206
Score = 75.5 bits (184), Expect = 6e-14, Method: Compositional matrix adjust.
Identities = 44/117 (37%), Positives = 60/117 (51%), Gaps = 1/117 (0%)
Frame = -2
Query: 475 KCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSL 534
+C C AI + AL +HPE F+CR+C + F G+P C Y ER S
Sbjct: 718 QCHKCNEAITSRVVFALGKNYHPEHFLCRDCDKQIKDDIFNIQQGEPVCNACYLERYTST 539
Query: 535 CSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQ-LNKGTFKEQNDKPYCQNCFLKLF 590
C+GC++PI G I+AM +H FVC KQ L +F E+ K YC+ + LF
Sbjct: 538 CAGCKEPIHGTTISAMGNNWHEHCFVCDGACKQPLKDSSFFEREGKAYCRQDYEDLF 368
>07437
Length = 951
Score = 126 bits (317), Expect = 2e-29, Method: Compositional matrix adjust.
Identities = 74/227 (32%), Positives = 110/227 (48%), Gaps = 7/227 (3%)
Frame = +3
Query: 370 VTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYC-----EKDYHNLFSPRCYYCNGPI 424
+ AM WHP+ F+C C + F + G+ C ++ C+ C+ I
Sbjct: 3 IKAMNSAWHPQCFLCQLCGTCMADSGFVKNAGRALCRECNAKEKARGTGKYVCHKCHDVI 182
Query: 425 -LDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAI 483
++ + +HP HF C CG E EKD + YC + + M P CG C R I
Sbjct: 183 EMNGHIKFRGEAYHPYHFNCHSCGVELNTEA-REKDSELYCLRCHDKMGIPICGACRRPI 359
Query: 484 LENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPIT 543
E + AL WH E FVC +C PF+ +E G YCE+HYH+ G++C C I
Sbjct: 360 EERVVHALGKAWHVEHFVCAKCEKPFLGTRHYEKKGLAYCEIHYHQLFGNICFVCNNIIN 539
Query: 544 GRCITAMAKKFHPEHFVCAFCLKQLNKGT-FKEQNDKPYCQNCFLKL 589
G +A K + HF C+ C +++++ T F E + KP C+NC+ K
Sbjct: 540 GDVFSAFNKAWCVHHFACSICDRKMSQKTKFFEFDQKPVCKNCYDKF 680
Score = 92.8 bits (229), Expect = 3e-19, Method: Compositional matrix adjust.
Identities = 53/139 (38%), Positives = 74/139 (53%), Gaps = 1/139 (0%)
Frame = +3
Query: 335 DSMLGSLQSDLNKLGVATVAKGVCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSR 394
DS L L+ +K+G+ +CGAC++PI +VV A+GK WH EHFVC C++
Sbjct: 285 DSELYCLRCH-DKMGIP-----ICGACRRPIEERVVHALGKAWHVEHFVCAKCEKPFLGT 446
Query: 395 NFFERDGQPYCEKDYHNLFSPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPE- 453
+E+ G YCE YH LF C+ CN I V +A ++ W HF C+ C +
Sbjct: 447 RHYEKKGLAYCEIHYHQLFGNICFVCNNIINGDVFSAFNKAWCVHHFACSICDRKMSQKT 626
Query: 454 GFHEKDGKAYCRKDYFDMF 472
F E D K C K+ +D F
Sbjct: 627 KFFEFDQKPVC-KNCYDKF 680
Score = 90.5 bits (223), Expect = 2e-18, Method: Compositional matrix adjust.
Identities = 62/182 (34%), Positives = 83/182 (45%), Gaps = 2/182 (1%)
Frame = +3
Query: 355 KGVCGACKKPI-AGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLF 413
K VC C I + G+ +HP HF C C E+ + E+D + YC + + +
Sbjct: 150 KYVCHKCHDVIEMNGHIKFRGEAYHPYHFNCHSCGVELNTEAR-EKDSELYCLRCHDKMG 326
Query: 414 SPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFA 473
P C C PI ++VV AL + WH EHF CA+C F +EK G AYC Y +F
Sbjct: 327 IPICGACRRPIEERVVHALGKAWHVEHFVCAKCEKPFLGTRHYEKKGLAYCEIHYHQLFG 506
Query: 474 PKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGS-FFEHDGQPYCEVHYHERRG 532
C C I + SA N W F C C + FFE D +P C+ Y + G
Sbjct: 507 NICFVCNNIINGDVFSAFNKAWCVHHFACSICDRKMSQKTKFFEFDQKPVCKNCYDKFPG 686
Query: 533 SL 534
L
Sbjct: 687 EL 692
Score = 71.2 bits (173), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 52/169 (30%), Positives = 77/169 (45%), Gaps = 7/169 (4%)
Frame = +3
Query: 429 VTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAP-----KCGGCARAI 483
+ A++ WHP+ F C CG GF + G+A CR+ A C C I
Sbjct: 3 IKAMNSAWHPQCFLCQLCGTCMADSGFVKNAGRALCRECNAKEKARGTGKYVCHKCHDVI 182
Query: 484 -LENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGS-LCSGCQKP 541
+ +I +HP F C C +N E D + YC + H++ G +C C++P
Sbjct: 183 EMNGHIKFRGEAYHPYHFNCHSCGVE-LNTEAREKDSELYC-LRCHDKMGIPICGACRRP 356
Query: 542 ITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 590
I R + A+ K +H EHFVCA C K E+ YC+ + +LF
Sbjct: 357 IEERVVHALGKAWHVEHFVCAKCEKPFLGTRHYEKKGLAYCEIHYHQLF 503
>14307
Length = 816
Score = 87.0 bits (214), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 59/197 (29%), Positives = 85/197 (43%), Gaps = 9/197 (4%)
Frame = +2
Query: 357 VCGACKKPIAGQ--VVTA----MGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYH 410
C CK I VVTA G WHP FVC+ C+E + + + D YC++ Y
Sbjct: 176 TCHCCKGEIDKLELVVTAPKVGEGTVWHPACFVCSTCEELLVDLVYCQHDKHLYCQRHYA 355
Query: 411 NLFSPRCYYCNGPILD-KVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYF 469
L PRC C+ I + A++ +H +H C QC + +D +C Y
Sbjct: 356 ELIRPRCPGCDELIFSGEYTKAMEECYHKDHLACWQCDKQLVSCRYIMRDDHPHCVPCYQ 535
Query: 470 DMFAPKCGGCARAILENY--ISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHY 527
+FA KC C + I +Y +S + WH CF C C V+ F + + +C Y
Sbjct: 536 ALFANKCEDCDKPIGPDYKDLSYKDKHWHEFCFKCTMCDKSLVDQPFAPKNEKIFCSECY 715
Query: 528 HERRGSLCSGCQKPITG 544
+ C GC P G
Sbjct: 716 DNSFAARCDGCGNPFKG 766
Score = 79.0 bits (193), Expect = 5e-15, Method: Compositional matrix adjust.
Identities = 52/183 (28%), Positives = 78/183 (42%), Gaps = 9/183 (4%)
Frame = +2
Query: 417 CYYCNGPI--LDKVVTALD----RTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFD 470
C+ C G I L+ VVTA WHP F C+ C + + D YC++ Y +
Sbjct: 179 CHCCKGEIDKLELVVTAPKVGEGTVWHPACFVCSTCEELLVDLVYCQHDKHLYCQRHYAE 358
Query: 471 MFAPKCGGCARAILE-NYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHE 529
+ P+C GC I Y A+ +H + C +C V+ + D P+C Y
Sbjct: 359 LIRPRCPGCDELIFSGEYTKAMEECYHKDHLACWQCDKQLVSCRYIMRDDHPHCVPCYQA 538
Query: 530 RRGSLCSGCQKPI--TGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFL 587
+ C C KPI + ++ K +H F C C K L F +N+K +C C+
Sbjct: 539 LFANKCEDCDKPIGPDYKDLSYKDKHWHEFCFKCTMCDKSLVDQPFAPKNEKIFCSECYD 718
Query: 588 KLF 590
F
Sbjct: 719 NSF 727
>05726
Length = 733
Score = 73.6 bits (179), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 42/135 (31%), Positives = 61/135 (45%), Gaps = 4/135 (2%)
Frame = +1
Query: 393 SRNFFERDGQPYCEKDYHNLFSPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGP 452
+++F RD + C Y N ++ RC+ C+ I ++ + WH E F C C
Sbjct: 1 NKSFIPRDDRVICVPCYENNYAQRCFKCSQVINKGGISYKNTPWHRECFTCTHCDKMLAG 180
Query: 453 EGFHEKDGKAYCRKDYFDMFAPKCGGCARAIL----ENYISALNTLWHPECFVCRECFTP 508
E F KD + YC + D+FA KC C +AI +IS WH +CF C +C
Sbjct: 181 EKFTSKDDQPYCGDCFGDLFAKKCCRCQKAITGIGGTKFISFEERHWHSDCFTCFKCQAS 360
Query: 509 FVNGSFFEHDGQPYC 523
V F +D C
Sbjct: 361 MVGRGFLMNDDDIVC 405
Score = 63.2 bits (152), Expect = 3e-10, Method: Compositional matrix adjust.
Identities = 37/124 (29%), Positives = 53/124 (42%), Gaps = 4/124 (3%)
Frame = +1
Query: 358 CGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRC 417
C C + I ++ WH E F CTHC + + F +D QPYC + +LF+ +C
Sbjct: 73 CFKCSQVINKGGISYKNTPWHRECFTCTHCDKMLAGEKFTSKDDQPYCGDCFGDLFAKKC 252
Query: 418 YYCNGPIL----DKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFA 473
C I K ++ +R WH + F C +C A GF D D+
Sbjct: 253 CRCQKAITGIGGTKFISFEERHWHSDCFTCFKCQASMVGRGFLMNDD---------DIVC 405
Query: 474 PKCG 477
P CG
Sbjct: 406 PDCG 417
Score = 62.8 bits (151), Expect = 4e-10, Method: Compositional matrix adjust.
Identities = 41/137 (29%), Positives = 60/137 (43%), Gaps = 4/137 (2%)
Frame = +1
Query: 453 EGFHEKDGKAYCRKDYFDMFAPKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNG 512
+ F +D + C Y + +A +C C++ I + IS NT WH ECF C C
Sbjct: 4 KSFIPRDDRVICVPCYENNYAQRCFKCSQVINKGGISYKNTPWHRECFTCTHCDKMLAGE 183
Query: 513 SFFEHDGQPYCEVHYHERRGSLCSGCQKPITG----RCITAMAKKFHPEHFVCAFCLKQL 568
F D QPYC + + C CQK ITG + I+ + +H + F C C +
Sbjct: 184 KFTSKDDQPYCGDCFGDLFAKKCCRCQKAITGIGGTKFISFEERHWHSDCFTCFKCQASM 363
Query: 569 NKGTFKEQNDKPYCQNC 585
F +D C +C
Sbjct: 364 VGRGFLMNDDDIVCPDC 414
Score = 42.7 bits (99), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 26/80 (32%), Positives = 34/80 (42%)
Frame = +1
Query: 511 NGSFFEHDGQPYCEVHYHERRGSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNK 570
N SF D + C Y C C + I I+ +H E F C C K L
Sbjct: 1 NKSFIPRDDRVICVPCYENNYAQRCFKCSQVINKGGISYKNTPWHRECFTCTHCDKMLAG 180
Query: 571 GTFKEQNDKPYCQNCFLKLF 590
F ++D+PYC +CF LF
Sbjct: 181 EKFTSKDDQPYCGDCFGDLF 240
>34420
Length = 719
Score = 43.9 bits (102), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 24/74 (32%), Positives = 34/74 (45%), Gaps = 4/74 (5%)
Frame = +2
Query: 395 NFFERDGQPYCEKDYHNLFSPRCYYCNGPIL----DKVVTALDRTWHPEHFFCAQCGAFF 450
F +D QPYC + LF+ RC C PI K ++ +R WH + F C +C A
Sbjct: 5 KFTSKDEQPYCGDCFGELFAKRCIRCTQPITGIGGTKFISFEERHWHSDCFVCYRCNASM 184
Query: 451 GPEGFHEKDGKAYC 464
GF + + C
Sbjct: 185 VGRGFLMQGEEILC 226
Score = 39.3 bits (90), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 23/75 (30%), Positives = 32/75 (42%), Gaps = 4/75 (5%)
Frame = +2
Query: 453 EGFHEKDGKAYCRKDYFDMFAPKCGGCARAIL----ENYISALNTLWHPECFVCRECFTP 508
E F KD + YC + ++FA +C C + I +IS WH +CFVC C
Sbjct: 2 EKFTSKDEQPYCGDCFGELFAKRCIRCTQPITGIGGTKFISFEERHWHSDCFVCYRCNAS 181
Query: 509 FVNGSFFEHDGQPYC 523
V F + C
Sbjct: 182 MVGRGFLMQGEEILC 226
Score = 34.7 bits (78), Expect = 0.11, Method: Compositional matrix adjust.
Identities = 23/76 (30%), Positives = 34/76 (44%), Gaps = 4/76 (5%)
Frame = +2
Query: 514 FFEHDGQPYCEVHYHERRGSLCSGCQKPITG----RCITAMAKKFHPEHFVCAFCLKQLN 569
F D QPYC + E C C +PITG + I+ + +H + FVC C +
Sbjct: 8 FTSKDEQPYCGDCFGELFAKRCIRCTQPITGIGGTKFISFEERHWHSDCFVCYRCNASMV 187
Query: 570 KGTFKEQNDKPYCQNC 585
F Q ++ C +C
Sbjct: 188 GRGFLMQGEEILCPDC 235
Score = 28.9 bits (63), Expect = 6.5, Method: Compositional matrix adjust.
Identities = 14/52 (26%), Positives = 23/52 (44%), Gaps = 4/52 (7%)
Frame = +2
Query: 358 CGACKKPIAG----QVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYC 405
C C +PI G + ++ + WH + FVC C + R F + + C
Sbjct: 71 CIRCTQPITGIGGTKFISFEERHWHSDCFVCYRCNASMVGRGFLMQGEEILC 226
>26762
Length = 399
Score = 43.1 bits (100), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 23/66 (34%), Positives = 32/66 (48%), Gaps = 4/66 (6%)
Frame = +1
Query: 394 RNFFERDGQPYCEKDYHNLFSPRCYYCNGPIL----DKVVTALDRTWHPEHFFCAQCGAF 449
+ F RD +PYC + LF+ RC C PI + ++ +R WH + F CA C A
Sbjct: 1 QRFTSRDEKPYCAECLGELFAKRCTSCVKPITGIGGTRFISFEERHWHHDCFVCASCKAS 180
Query: 450 FGPEGF 455
GF
Sbjct: 181 LVGRGF 198
Score = 38.9 bits (89), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 21/65 (32%), Positives = 29/65 (44%), Gaps = 4/65 (6%)
Frame = +1
Query: 455 FHEKDGKAYCRKDYFDMFAPKCGGCARAIL----ENYISALNTLWHPECFVCRECFTPFV 510
F +D K YC + ++FA +C C + I +IS WH +CFVC C V
Sbjct: 7 FTSRDEKPYCAECLGELFAKRCTSCVKPITGIGGTRFISFEERHWHHDCFVCASCKASLV 186
Query: 511 NGSFF 515
F
Sbjct: 187 GRGFI 201
Score = 37.0 bits (84), Expect = 0.024, Method: Compositional matrix adjust.
Identities = 25/76 (32%), Positives = 32/76 (42%), Gaps = 4/76 (5%)
Frame = +1
Query: 514 FFEHDGQPYCEVHYHERRGSLCSGCQKPITG----RCITAMAKKFHPEHFVCAFCLKQLN 569
F D +PYC E C+ C KPITG R I+ + +H + FVCA C L
Sbjct: 7 FTSRDEKPYCAECLGELFAKRCTSCVKPITGIGGTRFISFEERHWHHDCFVCASCKASLV 186
Query: 570 KGTFKEQNDKPYCQNC 585
F C +C
Sbjct: 187 GRGFITDGPDILCPDC 234
Score = 30.4 bits (67), Expect = 2.3, Method: Compositional matrix adjust.
Identities = 14/44 (31%), Positives = 22/44 (50%), Gaps = 4/44 (9%)
Frame = +1
Query: 358 CGACKKPIAG----QVVTAMGKTWHPEHFVCTHCQEEIGSRNFF 397
C +C KPI G + ++ + WH + FVC C+ + R F
Sbjct: 70 CTSCVKPITGIGGTRFISFEERHWHHDCFVCASCKASLVGRGFI 201
>05103
Length = 1504
Score = 39.7 bits (91), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 17/56 (30%), Positives = 23/56 (41%)
Frame = +2
Query: 475 KCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHER 530
+CGGC + A +H CF C C FF D + YCE H ++
Sbjct: 641 RCGGCDMLATGVIVKANGVPYHVACFKCESCSMNLKQKGFFVVDDKLYCETHARQK 808
Score = 37.0 bits (84), Expect = 0.022, Method: Compositional matrix adjust.
Identities = 17/49 (34%), Positives = 22/49 (44%)
Frame = +2
Query: 358 CGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCE 406
CG C G +V A G +H F C C + + FF D + YCE
Sbjct: 644 CGGCDMLATGVIVKANGVPYHVACFKCESCSMNLKQKGFFVVDDKLYCE 790
Score = 30.8 bits (68), Expect = 1.6, Method: Compositional matrix adjust.
Identities = 16/49 (32%), Positives = 21/49 (42%)
Frame = +2
Query: 535 CSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQ 583
C GC TG + A +H F C C L + F +DK YC+
Sbjct: 644 CGGCDMLATGVIVKANGVPYHVACFKCESCSMNLKQKGFFVVDDKLYCE 790
>30169
Length = 426
Score = 35.0 bits (79), Expect = 0.087, Method: Composition-based stats.
Identities = 18/63 (28%), Positives = 29/63 (46%), Gaps = 1/63 (1%)
Frame = -1
Query: 357 VCGACKKPIA-GQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSP 415
+C C K + + V MGK +H F CT C++ + S + YC+ Y F P
Sbjct: 408 MCAVCGKAVYFAERVAGMGKVYHKACFKCTSCRKILDSTLLTQHQDNIYCKACYGKNFGP 229
Query: 416 RCY 418
+ +
Sbjct: 228 KGF 220
Score = 33.9 bits (76), Expect = 0.17, Method: Composition-based stats.
Identities = 17/58 (29%), Positives = 26/58 (44%), Gaps = 1/58 (1%)
Frame = -1
Query: 534 LCSGCQKPIT-GRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 590
+C+ C K + + M K +H F C C K L+ + D YC+ C+ K F
Sbjct: 408 MCAVCGKAVYFAERVAGMGKVYHKACFKCTSCRKILDSTLLTQHQDNIYCKACYGKNF 235
Score = 28.5 bits (62), Expect = 8.7, Method: Composition-based stats.
Identities = 13/58 (22%), Positives = 24/58 (41%), Gaps = 1/58 (1%)
Frame = -1
Query: 476 CGGCARAI-LENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRG 532
C C +A+ ++ + ++H CF C C + +H YC+ Y + G
Sbjct: 405 CAVCGKAVYFAERVAGMGKVYHKACFKCTSCRKILDSTLLTQHQDNIYCKACYGKNFG 232
>15283
Length = 402
Score = 30.4 bits (67), Expect = 1.9, Method: Compositional matrix adjust.
Identities = 15/43 (34%), Positives = 21/43 (48%)
Frame = +1
Query: 534 LCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQ 576
LC C + C+T KK +VC C+K +K FK+Q
Sbjct: 199 LCDKCPRSYHLHCVTPPLKKVPKGKWVCPVCVKSKSKKGFKQQ 327
>02288
Length = 859
Score = 29.3 bits (64), Expect = 4.4, Method: Compositional matrix adjust.
Identities = 17/52 (32%), Positives = 29/52 (55%), Gaps = 2/52 (3%)
Frame = +3
Query: 76 FIHQQPQSSSPVYGSSAKTSSVSNPQDSVGSPCSRVGEEEHV--YSFPNKQK 125
++H+ Q+ + ++GSS TS S ++G P R+ + HV YS P + K
Sbjct: 582 YVHELSQTCANMHGSSCVTSCSSGEYTAIGLPEMRL*AKNHVICYSRPQETK 737
>17933
Length = 842
Score = 28.9 bits (63), Expect = 6.2, Method: Compositional matrix adjust.
Identities = 13/33 (39%), Positives = 21/33 (63%)
Frame = +1
Query: 479 CARAILENYISALNTLWHPECFVCRECFTPFVN 511
C+ +++E + NT++ CFV +CFT FVN
Sbjct: 613 CSNSLVEL*MFGYNTIFFLSCFVN*KCFTLFVN 711
>04349
Length = 1161
Score = 28.5 bits (62), Expect = 7.0, Method: Compositional matrix adjust.
Identities = 14/54 (25%), Positives = 20/54 (37%), Gaps = 1/54 (1%)
Frame = +3
Query: 475 KCGGCARAILE-NYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHY 527
KCG C + + I +H CF C C +F + +C HY
Sbjct: 228 KCGACHKTVYAMEKIEIEKNAYHKSCFRCSHCHCVLTPKTFAINKNVMFCTNHY 389
>12399
Length = 449
Score = 26.9 bits (58), Expect(2) = 9.9, Method: Composition-based stats.
Identities = 8/16 (50%), Positives = 11/16 (68%)
Frame = -2
Query: 493 TLWHPECFVCRECFTP 508
T W P+C VCR+ +P
Sbjct: 265 TFWPPKCLVCRDWLSP 218
Score = 19.6 bits (39), Expect(2) = 9.9, Method: Compositional matrix adjust.
Identities = 7/8 (87%), Positives = 7/8 (87%)
Frame = -3
Query: 534 LCSGCQKP 541
LCSGCQ P
Sbjct: 189 LCSGCQTP 166
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000267257 | hsapiens_gene_ensembl | Paxillin.
[Source:Uniprot/SWISSPROT;Acc:P49023]
(605 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
11928 340 1e-93
09680 129 3e-30
07437 126 2e-29
14307 86 3e-17
05726 73 3e-13
34420 44 2e-04
26762 43 4e-04
05103 40 0.003
30169 35 0.096
15283 30 2.8
02288 29 4.4
17933 29 6.0
>11928
Length = 1623
Score = 340 bits (871), Expect = 1e-93, Method: Compositional matrix adjust.
Identities = 152/221 (68%), Positives = 176/221 (79%)
Frame = -2
Query: 364 VATVAKGVCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDY 423
V T KGVC AC KPI GQV+ A+G+TWH EHFVC HC++ +G+ NF+ERD YCE DY
Sbjct: 1622 VNTKKKGVCAACNKPIVGQVIAALGRTWHVEHFVCAHCEQPLGTSNFYERDSVAYCEVDY 1443
Query: 424 HNLFSPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYF 483
HNLF+PRC YCNGPI+DK +TAL++ WHPEHFFCAQCG FG E FHEK+GKAYCR DYF
Sbjct: 1442 HNLFAPRCAYCNGPIVDKCITALEKMWHPEHFFCAQCGRQFGDEDFHEKNGKAYCRDDYF 1263
Query: 484 DMFAPKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHE 543
MFAPKCGGC I+ENYISALN WHP+CF C EC PF GSF++HDG PYCE HYH
Sbjct: 1262 QMFAPKCGGCGMPIMENYISALNRQWHPQCFCCWECQAPFGTGSFYDHDGLPYCETHYHA 1083
Query: 544 RRGSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNK 584
++GSLC+ CQKPITGRCITAM KKFHPEH FCL+ L++
Sbjct: 1082 KKGSLCASCQKPITGRCITAMFKKFHPEH----FCLRLLHQ 972
Score = 140 bits (354), Expect = 1e-33, Method: Compositional matrix adjust.
Identities = 67/168 (39%), Positives = 94/168 (55%)
Frame = -2
Query: 431 CYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKC 490
C CN PI+ +V+ AL RTWH EHF CA C G F+E+D AYC DY ++FAP+C
Sbjct: 1598 CAACNKPIVGQVIAALGRTWHVEHFVCAHCEQPLGTSNFYERDSVAYCEVDYHNLFAPRC 1419
Query: 491 GGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCS 550
C I++ I+AL +WHPE F C +C F + F E +G+ YC Y + C
Sbjct: 1418 AYCNGPIVDKCITALEKMWHPEHFFCAQCGRQFGDEDFHEKNGKAYCRDDYFQMFAPKCG 1239
Query: 551 GCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQN 598
GC PI I+A+ +++HP+ F C C G+F + + PYC+
Sbjct: 1238 GCGMPIMENYISALNRQWHPQCFCCWECQAPFGTGSFYDHDGLPYCET 1095
Score = 102 bits (253), Expect = 5e-22, Method: Compositional matrix adjust.
Identities = 48/115 (41%), Positives = 64/115 (55%)
Frame = -2
Query: 490 CGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLC 549
C C + I+ I+AL WH E FVC C P +F+E D YCEV YH C
Sbjct: 1598 CAACNKPIVGQVIAALGRTWHVEHFVCAHCEQPLGTSNFYERDSVAYCEVDYHNLFAPRC 1419
Query: 550 SGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 604
+ C PI +CITA+ K +HPEHF CA C +Q F E+N K YC++ + ++F
Sbjct: 1418 AYCNGPIVDKCITALEKMWHPEHFFCAQCGRQFGDEDFHEKNGKAYCRDDYFQMF 1254
Score = 69.7 bits (169), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 29/40 (72%), Positives = 33/40 (82%)
Frame = -3
Query: 565 AKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 604
++ F FVCAFC+KQLNKGTFKEQNDKPYC CF+KLF
Sbjct: 1018 SRSFTRSIFVCAFCIKQLNKGTFKEQNDKPYCHPCFVKLF 899
Score = 53.5 bits (127), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 23/61 (37%), Positives = 36/61 (59%)
Frame = -2
Query: 544 RRGSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKL 603
++ +C+ C KPI G+ I A+ + +H EHFVCA C + L F E++ YC+ + L
Sbjct: 1613 KKKGVCAACNKPIVGQVIAALGRTWHVEHFVCAHCEQPLGTSNFYERDSVAYCEVDYHNL 1434
Query: 604 F 604
F
Sbjct: 1433 F 1431
Score = 30.0 bits (66), Expect = 3.1, Method: Compositional matrix adjust.
Identities = 11/32 (34%), Positives = 18/32 (56%)
Frame = -3
Query: 396 FVCTHCQEEIGSRNFFERDGQPYCEKDYHNLF 427
FVC C +++ F E++ +PYC + LF
Sbjct: 994 FVCAFCIKQLNKGTFKEQNDKPYCHPCFVKLF 899
>09680
Length = 878
Score = 129 bits (325), Expect = 3e-30, Method: Compositional matrix adjust.
Identities = 65/177 (36%), Positives = 91/177 (51%), Gaps = 3/177 (1%)
Frame = -2
Query: 364 VATVAKGV--CGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEK 421
+A +AK C C + I +VV A+GK +HPEHF+C C ++I F + G+P C
Sbjct: 745 IALIAKQQYQCHKCNEAITSRVVFALGKNYHPEHFLCRDCDKQIKDDIFNIQQGEPVCNA 566
Query: 422 DYHNLFSPRCYYCNGPILDKVVTALDRTWHPEHFFC-AQCGAFFGPEGFHEKDGKAYCRK 480
Y ++ C C PI ++A+ WH F C C F E++GKAYCR+
Sbjct: 565 CYLERYTSTCAGCKEPIHGTTISAMGNNWHEHCFVCDGACKQPLKDSSFFEREGKAYCRQ 386
Query: 481 DYFDMFAPKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYC 537
DY D+FA +C C + I EN I A+N WH +CF C C P +F +P C
Sbjct: 385 DYEDLFAVRCAKCEKPITENAIVAMNAKWHSDCFCCNRCDNPIKTKTFTIEGDKPIC 215
Score = 120 bits (301), Expect = 2e-27, Method: Compositional matrix adjust.
Identities = 63/171 (36%), Positives = 85/171 (49%), Gaps = 1/171 (0%)
Frame = -2
Query: 430 RCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPK 489
+C+ CN I +VV AL + +HPEHF C C + F+ + G+ C Y + +
Sbjct: 718 QCHKCNEAITSRVVFALGKNYHPEHFLCRDCDKQIKDDIFNIQQGEPVCNACYLERYTST 539
Query: 490 CGGCARAILENYISALNTLWHPECFVCR-ECFTPFVNGSFFEHDGQPYCEVHYHERRGSL 548
C GC I ISA+ WH CFVC C P + SFFE +G+ YC Y +
Sbjct: 538 CAGCKEPIHGTTISAMGNNWHEHCFVCDGACKQPLKDSSFFEREGKAYCRQDYEDLFAVR 359
Query: 549 CSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNC 599
C+ C+KPIT I AM K+H + F C C + TF + DKP C C
Sbjct: 358 CAKCEKPITENAIVAMNAKWHSDCFCCNRCDNPIKTKTFTIEGDKPICPAC 206
Score = 75.9 bits (185), Expect = 5e-14, Method: Compositional matrix adjust.
Identities = 44/117 (37%), Positives = 60/117 (51%), Gaps = 1/117 (0%)
Frame = -2
Query: 489 KCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSL 548
+C C AI + AL +HPE F+CR+C + F G+P C Y ER S
Sbjct: 718 QCHKCNEAITSRVVFALGKNYHPEHFLCRDCDKQIKDDIFNIQQGEPVCNACYLERYTST 539
Query: 549 CSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQ-LNKGTFKEQNDKPYCQNCFLKLF 604
C+GC++PI G I+AM +H FVC KQ L +F E+ K YC+ + LF
Sbjct: 538 CAGCKEPIHGTTISAMGNNWHEHCFVCDGACKQPLKDSSFFEREGKAYCRQDYEDLF 368
>07437
Length = 951
Score = 126 bits (317), Expect = 2e-29, Method: Compositional matrix adjust.
Identities = 74/227 (32%), Positives = 110/227 (48%), Gaps = 7/227 (3%)
Frame = +3
Query: 384 VTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYC-----EKDYHNLFSPRCYYCNGPI 438
+ AM WHP+ F+C C + F + G+ C ++ C+ C+ I
Sbjct: 3 IKAMNSAWHPQCFLCQLCGTCMADSGFVKNAGRALCRECNAKEKARGTGKYVCHKCHDVI 182
Query: 439 -LDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAI 497
++ + +HP HF C CG E EKD + YC + + M P CG C R I
Sbjct: 183 EMNGHIKFRGEAYHPYHFNCHSCGVELNTEA-REKDSELYCLRCHDKMGIPICGACRRPI 359
Query: 498 LENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPIT 557
E + AL WH E FVC +C PF+ +E G YCE+HYH+ G++C C I
Sbjct: 360 EERVVHALGKAWHVEHFVCAKCEKPFLGTRHYEKKGLAYCEIHYHQLFGNICFVCNNIIN 539
Query: 558 GRCITAMAKKFHPEHFVCAFCLKQLNKGT-FKEQNDKPYCQNCFLKL 603
G +A K + HF C+ C +++++ T F E + KP C+NC+ K
Sbjct: 540 GDVFSAFNKAWCVHHFACSICDRKMSQKTKFFEFDQKPVCKNCYDKF 680
Score = 92.8 bits (229), Expect = 4e-19, Method: Compositional matrix adjust.
Identities = 53/139 (38%), Positives = 74/139 (53%), Gaps = 1/139 (0%)
Frame = +3
Query: 349 DSMLGSLQSDLNKLGVATVAKGVCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSR 408
DS L L+ +K+G+ +CGAC++PI +VV A+GK WH EHFVC C++
Sbjct: 285 DSELYCLRCH-DKMGIP-----ICGACRRPIEERVVHALGKAWHVEHFVCAKCEKPFLGT 446
Query: 409 NFFERDGQPYCEKDYHNLFSPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPE- 467
+E+ G YCE YH LF C+ CN I V +A ++ W HF C+ C +
Sbjct: 447 RHYEKKGLAYCEIHYHQLFGNICFVCNNIINGDVFSAFNKAWCVHHFACSICDRKMSQKT 626
Query: 468 GFHEKDGKAYCRKDYFDMF 486
F E D K C K+ +D F
Sbjct: 627 KFFEFDQKPVC-KNCYDKF 680
Score = 90.1 bits (222), Expect = 2e-18, Method: Compositional matrix adjust.
Identities = 62/183 (33%), Positives = 83/183 (45%), Gaps = 2/183 (1%)
Frame = +3
Query: 368 AKGVCGACKKPI-AGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNL 426
K VC C I + G+ +HP HF C C E+ + E+D + YC + + +
Sbjct: 147 GKYVCHKCHDVIEMNGHIKFRGEAYHPYHFNCHSCGVELNTEAR-EKDSELYCLRCHDKM 323
Query: 427 FSPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMF 486
P C C PI ++VV AL + WH EHF CA+C F +EK G AYC Y +F
Sbjct: 324 GIPICGACRRPIEERVVHALGKAWHVEHFVCAKCEKPFLGTRHYEKKGLAYCEIHYHQLF 503
Query: 487 APKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGS-FFEHDGQPYCEVHYHERR 545
C C I + SA N W F C C + FFE D +P C+ Y +
Sbjct: 504 GNICFVCNNIINGDVFSAFNKAWCVHHFACSICDRKMSQKTKFFEFDQKPVCKNCYDKFP 683
Query: 546 GSL 548
G L
Sbjct: 684 GEL 692
Score = 71.2 bits (173), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 52/169 (30%), Positives = 77/169 (45%), Gaps = 7/169 (4%)
Frame = +3
Query: 443 VTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPK-----CGGCARAI 497
+ A++ WHP+ F C CG GF + G+A CR+ A C C I
Sbjct: 3 IKAMNSAWHPQCFLCQLCGTCMADSGFVKNAGRALCRECNAKEKARGTGKYVCHKCHDVI 182
Query: 498 -LENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGS-LCSGCQKP 555
+ +I +HP F C C +N E D + YC + H++ G +C C++P
Sbjct: 183 EMNGHIKFRGEAYHPYHFNCHSCGVE-LNTEAREKDSELYC-LRCHDKMGIPICGACRRP 356
Query: 556 ITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 604
I R + A+ K +H EHFVCA C K E+ YC+ + +LF
Sbjct: 357 IEERVVHALGKAWHVEHFVCAKCEKPFLGTRHYEKKGLAYCEIHYHQLF 503
>14307
Length = 816
Score = 86.3 bits (212), Expect = 3e-17, Method: Compositional matrix adjust.
Identities = 60/197 (30%), Positives = 85/197 (43%), Gaps = 9/197 (4%)
Frame = +2
Query: 371 VCGACKKPIAGQ--VVTA----MGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYH 424
C CK I VVTA G WHP FVC+ C+E + + + D YC++ Y
Sbjct: 176 TCHCCKGEIDKLELVVTAPKVGEGTVWHPACFVCSTCEELLVDLVYCQHDKHLYCQRHYA 355
Query: 425 NLFSPRCYYCNGPILDKVVT-ALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYF 483
L PRC C+ I T A++ +H +H C QC + +D +C Y
Sbjct: 356 ELIRPRCPGCDELIFSGEYTKAMEECYHKDHLACWQCDKQLVSCRYIMRDDHPHCVPCYQ 535
Query: 484 DMFAPKCGGCARAILENY--ISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHY 541
+FA KC C + I +Y +S + WH CF C C V+ F + + +C Y
Sbjct: 536 ALFANKCEDCDKPIGPDYKDLSYKDKHWHEFCFKCTMCDKSLVDQPFAPKNEKIFCSECY 715
Query: 542 HERRGSLCSGCQKPITG 558
+ C GC P G
Sbjct: 716 DNSFAARCDGCGNPFKG 766
Score = 78.2 bits (191), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 52/183 (28%), Positives = 78/183 (42%), Gaps = 9/183 (4%)
Frame = +2
Query: 431 CYYCNGPI--LDKVVTA----LDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFD 484
C+ C G I L+ VVTA WHP F C+ C + + D YC++ Y +
Sbjct: 179 CHCCKGEIDKLELVVTAPKVGEGTVWHPACFVCSTCEELLVDLVYCQHDKHLYCQRHYAE 358
Query: 485 MFAPKCGGCARAILE-NYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHE 543
+ P+C GC I Y A+ +H + C +C V+ + D P+C Y
Sbjct: 359 LIRPRCPGCDELIFSGEYTKAMEECYHKDHLACWQCDKQLVSCRYIMRDDHPHCVPCYQA 538
Query: 544 RRGSLCSGCQKPI--TGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFL 601
+ C C KPI + ++ K +H F C C K L F +N+K +C C+
Sbjct: 539 LFANKCEDCDKPIGPDYKDLSYKDKHWHEFCFKCTMCDKSLVDQPFAPKNEKIFCSECYD 718
Query: 602 KLF 604
F
Sbjct: 719 NSF 727
>05726
Length = 733
Score = 73.2 bits (178), Expect = 3e-13, Method: Compositional matrix adjust.
Identities = 42/135 (31%), Positives = 61/135 (45%), Gaps = 4/135 (2%)
Frame = +1
Query: 407 SRNFFERDGQPYCEKDYHNLFSPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGP 466
+++F RD + C Y N ++ RC+ C+ I ++ + WH E F C C
Sbjct: 1 NKSFIPRDDRVICVPCYENNYAQRCFKCSQVINKGGISYKNTPWHRECFTCTHCDKMLAG 180
Query: 467 EGFHEKDGKAYCRKDYFDMFAPKCGGCARAIL----ENYISALNTLWHPECFVCRECFTP 522
E F KD + YC + D+FA KC C +AI +IS WH +CF C +C
Sbjct: 181 EKFTSKDDQPYCGDCFGDLFAKKCCRCQKAITGIGGTKFISFEERHWHSDCFTCFKCQAS 360
Query: 523 FVNGSFFEHDGQPYC 537
V F +D C
Sbjct: 361 MVGRGFLMNDDDIVC 405
Score = 63.2 bits (152), Expect = 3e-10, Method: Compositional matrix adjust.
Identities = 37/124 (29%), Positives = 53/124 (42%), Gaps = 4/124 (3%)
Frame = +1
Query: 372 CGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRC 431
C C + I ++ WH E F CTHC + + F +D QPYC + +LF+ +C
Sbjct: 73 CFKCSQVINKGGISYKNTPWHRECFTCTHCDKMLAGEKFTSKDDQPYCGDCFGDLFAKKC 252
Query: 432 YYCNGPIL----DKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFA 487
C I K ++ +R WH + F C +C A GF D D+
Sbjct: 253 CRCQKAITGIGGTKFISFEERHWHSDCFTCFKCQASMVGRGFLMNDD---------DIVC 405
Query: 488 PKCG 491
P CG
Sbjct: 406 PDCG 417
Score = 62.8 bits (151), Expect = 4e-10, Method: Compositional matrix adjust.
Identities = 41/137 (29%), Positives = 60/137 (43%), Gaps = 4/137 (2%)
Frame = +1
Query: 467 EGFHEKDGKAYCRKDYFDMFAPKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNG 526
+ F +D + C Y + +A +C C++ I + IS NT WH ECF C C
Sbjct: 4 KSFIPRDDRVICVPCYENNYAQRCFKCSQVINKGGISYKNTPWHRECFTCTHCDKMLAGE 183
Query: 527 SFFEHDGQPYCEVHYHERRGSLCSGCQKPITG----RCITAMAKKFHPEHFVCAFCLKQL 582
F D QPYC + + C CQK ITG + I+ + +H + F C C +
Sbjct: 184 KFTSKDDQPYCGDCFGDLFAKKCCRCQKAITGIGGTKFISFEERHWHSDCFTCFKCQASM 363
Query: 583 NKGTFKEQNDKPYCQNC 599
F +D C +C
Sbjct: 364 VGRGFLMNDDDIVCPDC 414
Score = 42.4 bits (98), Expect = 5e-04, Method: Compositional matrix adjust.
Identities = 26/80 (32%), Positives = 34/80 (42%)
Frame = +1
Query: 525 NGSFFEHDGQPYCEVHYHERRGSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNK 584
N SF D + C Y C C + I I+ +H E F C C K L
Sbjct: 1 NKSFIPRDDRVICVPCYENNYAQRCFKCSQVINKGGISYKNTPWHRECFTCTHCDKMLAG 180
Query: 585 GTFKEQNDKPYCQNCFLKLF 604
F ++D+PYC +CF LF
Sbjct: 181 EKFTSKDDQPYCGDCFGDLF 240
>34420
Length = 719
Score = 43.9 bits (102), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 24/74 (32%), Positives = 34/74 (45%), Gaps = 4/74 (5%)
Frame = +2
Query: 409 NFFERDGQPYCEKDYHNLFSPRCYYCNGPILD----KVVTALDRTWHPEHFFCAQCGAFF 464
F +D QPYC + LF+ RC C PI K ++ +R WH + F C +C A
Sbjct: 5 KFTSKDEQPYCGDCFGELFAKRCIRCTQPITGIGGTKFISFEERHWHSDCFVCYRCNASM 184
Query: 465 GPEGFHEKDGKAYC 478
GF + + C
Sbjct: 185 VGRGFLMQGEEILC 226
Score = 38.9 bits (89), Expect = 0.007, Method: Compositional matrix adjust.
Identities = 23/75 (30%), Positives = 32/75 (42%), Gaps = 4/75 (5%)
Frame = +2
Query: 467 EGFHEKDGKAYCRKDYFDMFAPKCGGCARAIL----ENYISALNTLWHPECFVCRECFTP 522
E F KD + YC + ++FA +C C + I +IS WH +CFVC C
Sbjct: 2 EKFTSKDEQPYCGDCFGELFAKRCIRCTQPITGIGGTKFISFEERHWHSDCFVCYRCNAS 181
Query: 523 FVNGSFFEHDGQPYC 537
V F + C
Sbjct: 182 MVGRGFLMQGEEILC 226
Score = 34.7 bits (78), Expect = 0.13, Method: Compositional matrix adjust.
Identities = 23/76 (30%), Positives = 34/76 (44%), Gaps = 4/76 (5%)
Frame = +2
Query: 528 FFEHDGQPYCEVHYHERRGSLCSGCQKPITG----RCITAMAKKFHPEHFVCAFCLKQLN 583
F D QPYC + E C C +PITG + I+ + +H + FVC C +
Sbjct: 8 FTSKDEQPYCGDCFGELFAKRCIRCTQPITGIGGTKFISFEERHWHSDCFVCYRCNASMV 187
Query: 584 KGTFKEQNDKPYCQNC 599
F Q ++ C +C
Sbjct: 188 GRGFLMQGEEILCPDC 235
Score = 28.5 bits (62), Expect = 7.5, Method: Compositional matrix adjust.
Identities = 14/52 (26%), Positives = 23/52 (44%), Gaps = 4/52 (7%)
Frame = +2
Query: 372 CGACKKPIAG----QVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYC 419
C C +PI G + ++ + WH + FVC C + R F + + C
Sbjct: 71 CIRCTQPITGIGGTKFISFEERHWHSDCFVCYRCNASMVGRGFLMQGEEILC 226
>26762
Length = 399
Score = 42.7 bits (99), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 23/66 (34%), Positives = 32/66 (48%), Gaps = 4/66 (6%)
Frame = +1
Query: 408 RNFFERDGQPYCEKDYHNLFSPRCYYCNGPIL----DKVVTALDRTWHPEHFFCAQCGAF 463
+ F RD +PYC + LF+ RC C PI + ++ +R WH + F CA C A
Sbjct: 1 QRFTSRDEKPYCAECLGELFAKRCTSCVKPITGIGGTRFISFEERHWHHDCFVCASCKAS 180
Query: 464 FGPEGF 469
GF
Sbjct: 181 LVGRGF 198
Score = 38.5 bits (88), Expect = 0.008, Method: Compositional matrix adjust.
Identities = 21/65 (32%), Positives = 29/65 (44%), Gaps = 4/65 (6%)
Frame = +1
Query: 469 FHEKDGKAYCRKDYFDMFAPKCGGCARAIL----ENYISALNTLWHPECFVCRECFTPFV 524
F +D K YC + ++FA +C C + I +IS WH +CFVC C V
Sbjct: 7 FTSRDEKPYCAECLGELFAKRCTSCVKPITGIGGTRFISFEERHWHHDCFVCASCKASLV 186
Query: 525 NGSFF 529
F
Sbjct: 187 GRGFI 201
Score = 36.6 bits (83), Expect = 0.028, Method: Compositional matrix adjust.
Identities = 25/76 (32%), Positives = 32/76 (42%), Gaps = 4/76 (5%)
Frame = +1
Query: 528 FFEHDGQPYCEVHYHERRGSLCSGCQKPITG----RCITAMAKKFHPEHFVCAFCLKQLN 583
F D +PYC E C+ C KPITG R I+ + +H + FVCA C L
Sbjct: 7 FTSRDEKPYCAECLGELFAKRCTSCVKPITGIGGTRFISFEERHWHHDCFVCASCKASLV 186
Query: 584 KGTFKEQNDKPYCQNC 599
F C +C
Sbjct: 187 GRGFITDGPDILCPDC 234
Score = 30.0 bits (66), Expect = 2.5, Method: Compositional matrix adjust.
Identities = 14/44 (31%), Positives = 22/44 (50%), Gaps = 4/44 (9%)
Frame = +1
Query: 372 CGACKKPIAG----QVVTAMGKTWHPEHFVCTHCQEEIGSRNFF 411
C +C KPI G + ++ + WH + FVC C+ + R F
Sbjct: 70 CTSCVKPITGIGGTRFISFEERHWHHDCFVCASCKASLVGRGFI 201
>05103
Length = 1504
Score = 40.0 bits (92), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 17/56 (30%), Positives = 23/56 (41%)
Frame = +2
Query: 489 KCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHER 544
+CGGC + A +H CF C C FF D + YCE H ++
Sbjct: 641 RCGGCDMLATGVIVKANGVPYHVACFKCESCSMNLKQKGFFVVDDKLYCETHARQK 808
Score = 37.4 bits (85), Expect = 0.020, Method: Compositional matrix adjust.
Identities = 17/49 (34%), Positives = 22/49 (44%)
Frame = +2
Query: 372 CGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCE 420
CG C G +V A G +H F C C + + FF D + YCE
Sbjct: 644 CGGCDMLATGVIVKANGVPYHVACFKCESCSMNLKQKGFFVVDDKLYCE 790
Score = 31.2 bits (69), Expect = 1.3, Method: Compositional matrix adjust.
Identities = 16/49 (32%), Positives = 21/49 (42%)
Frame = +2
Query: 549 CSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQ 597
C GC TG + A +H F C C L + F +DK YC+
Sbjct: 644 CGGCDMLATGVIVKANGVPYHVACFKCESCSMNLKQKGFFVVDDKLYCE 790
>30169
Length = 426
Score = 35.0 bits (79), Expect = 0.096, Method: Composition-based stats.
Identities = 18/63 (28%), Positives = 29/63 (46%), Gaps = 1/63 (1%)
Frame = -1
Query: 371 VCGACKKPIA-GQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSP 429
+C C K + + V MGK +H F CT C++ + S + YC+ Y F P
Sbjct: 408 MCAVCGKAVYFAERVAGMGKVYHKACFKCTSCRKILDSTLLTQHQDNIYCKACYGKNFGP 229
Query: 430 RCY 432
+ +
Sbjct: 228 KGF 220
Score = 33.9 bits (76), Expect = 0.17, Method: Composition-based stats.
Identities = 17/58 (29%), Positives = 26/58 (44%), Gaps = 1/58 (1%)
Frame = -1
Query: 548 LCSGCQKPIT-GRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 604
+C+ C K + + M K +H F C C K L+ + D YC+ C+ K F
Sbjct: 408 MCAVCGKAVYFAERVAGMGKVYHKACFKCTSCRKILDSTLLTQHQDNIYCKACYGKNF 235
Score = 28.5 bits (62), Expect = 8.1, Method: Composition-based stats.
Identities = 13/58 (22%), Positives = 24/58 (41%), Gaps = 1/58 (1%)
Frame = -1
Query: 490 CGGCARAI-LENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRG 546
C C +A+ ++ + ++H CF C C + +H YC+ Y + G
Sbjct: 405 CAVCGKAVYFAERVAGMGKVYHKACFKCTSCRKILDSTLLTQHQDNIYCKACYGKNFG 232
>15283
Length = 402
Score = 30.0 bits (66), Expect = 2.8, Method: Compositional matrix adjust.
Identities = 15/43 (34%), Positives = 21/43 (48%)
Frame = +1
Query: 548 LCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQ 590
LC C + C+T KK +VC C+K +K FK+Q
Sbjct: 199 LCDKCPRSYHLHCVTPPLKKVPKGKWVCPVCVKSKSKKGFKQQ 327
>02288
Length = 859
Score = 29.3 bits (64), Expect = 4.4, Method: Compositional matrix adjust.
Identities = 17/52 (32%), Positives = 29/52 (55%), Gaps = 2/52 (3%)
Frame = +3
Query: 76 FIHQQPQSSSPVYGSSAKTSSVSNPQDSVGSPCSRVGEEEHV--YSFPNKQK 125
++H+ Q+ + ++GSS TS S ++G P R+ + HV YS P + K
Sbjct: 582 YVHELSQTCANMHGSSCVTSCSSGEYTAIGLPEMRL*AKNHVICYSRPQETK 737
>17933
Length = 842
Score = 28.9 bits (63), Expect = 6.0, Method: Compositional matrix adjust.
Identities = 13/33 (39%), Positives = 21/33 (63%)
Frame = +1
Query: 493 CARAILENYISALNTLWHPECFVCRECFTPFVN 525
C+ +++E + NT++ CFV +CFT FVN
Sbjct: 613 CSNSLVEL*MFGYNTIFFLSCFVN*KCFTLFVN 711
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000245544 | hsapiens_gene_ensembl | nucleoporin 85
[Source:RefSeq_peptide;Acc:NP_079120]
(656 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
10207 338 5e-93
30620 60 2e-09
21696 39 0.005
14867 35 0.12
35601 30 3.7
>10207
Length = 1209
Score = 338 bits (866), Expect = 5e-93, Method: Compositional matrix adjust.
Identities = 170/344 (49%), Positives = 232/344 (67%), Gaps = 28/344 (8%)
Frame = +2
Query: 316 NPTVKPIDLHYYAQSSLDLFLG-GESSPEPL------------------DNILLAAFEFD 356
NP KP + Q +D F G G S+ PL DNIL AA EFD
Sbjct: 11 NPKHKPNKEPKFHQ--IDRFDGAGRSTKAPLTTFKIG*IFRIGLRMGSIDNILQAALEFD 184
Query: 357 IHQVIKECSIALSN--WWFVAHLTDLLDHCKLLQSHNLYFGSNMREFLLLEYASGLFAHP 414
+HQVIK+ S L + WWF AHLTD+L HC + S L FGSN+RE+LLLEY +GL +H
Sbjct: 185 LHQVIKDSSTCLGDRSWWFSAHLTDILHHCGQIDSQKLAFGSNLREYLLLEYVAGLMSHN 364
Query: 415 SLWQLGVDYFDYCPELGRVSLELHIERIPLNTEQKALKVLRICEQRQMTEQVRSICKILA 474
SLWQ+G+DY D+CP G+ ++L+IE IPL+TE+KA K++ +CE+R++ EQV+SICKI+
Sbjct: 365 SLWQVGIDYLDHCPVFGKEHMKLYIENIPLDTERKANKLIHVCEERELVEQVQSICKIMG 544
Query: 475 MKAVRNNRLGSALSWSIRAKDAAFATLVSDRFLRDYCERGCFSDLDLIDNLGPAMMLSDR 534
++ + RLGSALSW +R+KD + AT ++++FL +Y E G FS LDL+D+LGP M+L+ +
Sbjct: 545 VRCSQEGRLGSALSWFLRSKDVSAATRLTEKFLEEYKEHGSFSHLDLLDHLGPTMLLTQQ 724
Query: 535 LTFLGKYREFHRMYGEKRFADAASLLLSLMTSRIAPRSFWMTLLTDALPLLEQKQVIFSA 594
LTFLGKYREFHR+Y ++ AASLLL+++T+R APR FW+TLL DA+PLLE QV+ +
Sbjct: 725 LTFLGKYREFHRLYQDRDVKGAASLLLNMLTARAAPRHFWVTLLMDAMPLLETPQVVLGS 904
Query: 595 EQTYELMRCLEDLT-------SRRPVHGESDTEQLQDDDIETTK 631
QTYELM CLE+LT ++DT+ L D++ K
Sbjct: 905 NQTYELMHCLEELTQELTKTKKNSTPQPDTDTQMLSQGDLDKLK 1036
>30620
Length = 413
Score = 60.5 bits (145), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 30/89 (33%), Positives = 51/89 (57%)
Frame = +2
Query: 57 IRKDVDVYSQILRKLFNESHGIFLGLQRIDEELTGKSRKSQLVRVSKNYRSVIRACMEEM 116
+R D++ RKL NESH +F+ LQ LTG + +QL S+ YRS+ +AC E+
Sbjct: 65 VRWGQDMHGATTRKLINESHSVFVMLQGQVTSLTGTALYNQLKEASRQYRSIAKACSLEL 244
Query: 117 HQVAIAAKDPANGRQFSSQVSILSAMELI 145
++ + D +S+Q+ +L +M+L+
Sbjct: 245 QRLLFESSDNGEKDYYSNQIELLESMQLV 331
>21696
Length = 398
Score = 39.3 bits (90), Expect = 0.005, Method: Composition-based stats.
Identities = 16/29 (55%), Positives = 23/29 (79%)
Frame = +2
Query: 466 VRSICKILAMKAVRNNRLGSALSWSIRAK 494
V+SICKI+ ++ + RLGSALSW +R+K
Sbjct: 86 VQSICKIMGVRCSQEGRLGSALSWFLRSK 172
>14867
Length = 453
Score = 34.7 bits (78), Expect = 0.12, Method: Composition-based stats.
Identities = 14/19 (73%), Positives = 16/19 (84%)
Frame = -3
Query: 572 SFWMTLLTDALPLLEQKQV 590
SFW+TLL DA+PLLE QV
Sbjct: 178 SFWVTLLMDAMPLLETPQV 122
>35601
Length = 195
Score = 29.6 bits (65), Expect = 3.7, Method: Composition-based stats.
Identities = 19/54 (35%), Positives = 26/54 (48%), Gaps = 5/54 (9%)
Frame = -1
Query: 511 CERG-----CFSDLDLIDNLGPAMMLSDRLTFLGKYREFHRMYGEKRFADAASL 559
CER C S L L P++++SDR G +F + G K F AAS+
Sbjct: 180 CERSLWRVHCLSSLRLNLTHRPSLLMSDRGLKTGGNTDFSHITGTKSFKMAASI 19
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000266970 | hsapiens_gene_ensembl | Cell division
protein kinase 2 (EC 2.7.11.22) (p33 protein kinase).
[Source:Uniprot/SWISSPROT;Acc:P24941]
(298 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
01060 333 4e-92
01966 197 2e-80
14126 259 8e-70
32000 237 4e-63
01756 232 1e-61
01707 216 1e-56
29581 195 2e-50
04591 178 2e-45
04138 152 1e-37
20559 112 1e-30
00300 113 8e-26
23319 110 1e-24
13592 108 2e-24
18921 108 3e-24
03294 106 1e-23
24241 104 5e-23
06405 100 6e-22
09606 96 1e-20
03508 96 2e-20
12721 96 2e-20
19761 91 4e-19
01718 91 5e-19
14420 90 9e-19
17975 85 3e-17
12453 83 2e-16
13066 80 1e-15
15910 79 2e-15
03240 78 4e-15
19301 74 6e-14
21808 74 8e-14
18484 73 1e-13
30755 73 2e-13
21433 60 3e-13
11780 71 6e-13
04852 70 1e-12
28638 70 1e-12
09007 70 1e-12
00392 69 2e-12
32359 60 2e-12
18287 69 2e-12
19094 69 2e-12
13212 66 1e-11
31885 66 2e-11
27546 65 3e-11
26560 65 3e-11
14477 63 1e-10
27405 62 3e-10
14116 61 5e-10
07940 61 6e-10
16003 60 9e-10
11185 60 1e-09
26711 59 2e-09
01106 59 2e-09
17253 59 3e-09
00715 57 8e-09
36481 57 9e-09
22005 57 1e-08
37602 44 5e-08
12786 55 5e-08
01392 54 6e-08
31489 53 1e-07
18401 52 2e-07
26009 39 3e-07
11404 52 3e-07
21079 51 6e-07
07291 51 7e-07
02638 50 1e-06
05084 50 1e-06
29360 49 2e-06
26909 49 3e-06
21800 47 1e-05
20640 45 4e-05
06358 45 5e-05
28157 44 5e-05
20152 44 6e-05
16708 44 1e-04
13078 43 1e-04
17300 43 1e-04
00638 42 3e-04
31789 42 4e-04
25019 42 4e-04
12672 40 0.001
15549 39 0.002
00394 38 0.005
38560 38 0.006
07836 37 0.007
18481 34 0.071
35032 34 0.091
00486 33 0.16
17806 33 0.19
17644 31 0.75
20773 30 0.94
15931 29 1.9
07833 29 2.3
20513 28 3.5
16350 28 3.5
08279 28 3.8
26565 28 5.2
>01060
Length = 1800
Score = 333 bits (855), Expect = 4e-92, Method: Compositional matrix adjust.
Identities = 161/295 (54%), Positives = 206/295 (69%), Gaps = 2/295 (0%)
Frame = +1
Query: 1 MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH 60
+ + +KIGEGTYGVVYK R++ TG +A+KKIRL +GVPS+AIREI++L+EL H
Sbjct: 70 LSDLTDFQKIGEGTYGVVYKCRHRATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELRH 249
Query: 61 PNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLP--LIKSYLFQLLQGLAFC 118
NIV L DVI + +L+LVFEFL DLK ++D G+ L L+KSY+FQ++ G+ FC
Sbjct: 250 TNIVCLEDVIMEDERLFLVFEFLSMDLKMYIDKFP-EGVVLDRRLVKSYVFQIVTGIXFC 426
Query: 119 HSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCK 178
H R++HRDLKPQNLLIN GAIK+ADFG+AR F +PVR YTHEVVTLWYRAPEIL+G
Sbjct: 427 HQRRIVHRDLKPQNLLINHTGAIKIADFGMARTFALPVRAYTHEVVTLWYRAPEILMGAS 606
Query: 179 YYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKP 238
YST VD+WS+G IFA+M+ R +F GDSEIDQLF+IFR +GTP E WP +P +
Sbjct: 607 KYSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKLPAFNG 786
Query: 239 SFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPV 293
FP W S+ + LD G L+ + L DP +RIS K L H +F +V V
Sbjct: 787 MFPLWKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYFLNVDTSV 951
>01966
Length = 1735
Score = 197 bits (502), Expect(3) = 2e-80, Method: Compositional matrix adjust.
Identities = 96/158 (60%), Positives = 122/158 (77%), Gaps = 2/158 (1%)
Frame = -1
Query: 21 ARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVF 80
R++ TG +A+KKIRL +GVPS+AIREI++L+EL H NIV L DVI + +L+LVF
Sbjct: 1654 CRHRATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTNIVCLEDVIMEDERLFLVF 1475
Query: 81 EFLHQDLKKFMDASALTGIPLP--LIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTE 138
EFL DLK ++D G+ L L+KSY+FQ++ G+ FCH R++HRDLKPQNLLIN
Sbjct: 1474 EFLSMDLKMYIDKFP-EGVVLDRRLVKSYVFQIVTGINFCHQRRIVHRDLKPQNLLINHT 1298
Query: 139 GAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLG 176
GAIK+ADFG+AR F +PVR YTHEVVTLWYRAPEIL+G
Sbjct: 1297 GAIKIADFGMARTFALPVRAYTHEVVTLWYRAPEILMG 1184
Score = 113 bits (283), Expect(3) = 2e-80, Method: Compositional matrix adjust.
Identities = 54/118 (45%), Positives = 70/118 (59%)
Frame = -3
Query: 176 GCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPD 235
G YST VD+WS+G IFA+M+ R +F GDSEIDQLF+IFR +GTP E WP +P
Sbjct: 1187 GASKYSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKLPA 1008
Query: 236 YKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPV 293
+ FP W S+ + LD G L+ + L DP +RIS K L H +F +V V
Sbjct: 1007 FNGMFPLWKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYFLNVDTSV 834
Score = 27.3 bits (59), Expect(3) = 2e-80, Method: Compositional matrix adjust.
Identities = 11/15 (73%), Positives = 13/15 (86%)
Frame = -2
Query: 6 KVEKIGEGTYGVVYK 20
++ KIGEGTYGVVY
Sbjct: 1698 RLSKIGEGTYGVVYN 1654
>14126
Length = 1265
Score = 259 bits (662), Expect = 8e-70, Method: Compositional matrix adjust.
Identities = 138/296 (46%), Positives = 191/296 (64%), Gaps = 9/296 (3%)
Frame = +3
Query: 2 ENFQKVEKIGEGTYGVVYKARN-KLTGEVVALKKIRLDTETEGVPSTAIREISLLKELN- 59
+ +++V IG G YG VYKAR+ + GE VA+K+IRL+ EG+P AIREIS+LK+L
Sbjct: 189 QKYEEVAVIGNGAYGTVYKARDLRNQGEFVAMKRIRLNNTEEGMPMMAIREISMLKQLEQ 368
Query: 60 --HPNIVKLLDVIHT-----ENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLL 112
HPN+V+LLDV H E +L LVFE++ DL ++ G+ IK + QLL
Sbjct: 369 YEHPNVVRLLDVSHNTITDREIRLNLVFEYIEHDLATYLAKCPSPGLGPDRIKDLMLQLL 548
Query: 113 QGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPE 172
G+ F HS+R++HRDLKPQNLLI+ +G +KLADFGLAR + + T VVTLWYR+PE
Sbjct: 549 NGVDFLHSNRIVHRDLKPQNLLISKDGRLKLADFGLARIYSFHM-ALTTVVVTLWYRSPE 725
Query: 173 ILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTS 232
+L+ + Y T+VDIWS GCIFAE+ TRRALF G SE DQL +IF +G P WP S
Sbjct: 726 VLMQAE-YGTSVDIWSCGCIFAELFTRRALFKGSSEFDQLKKIFEVIGLPPAGDWPEGVS 902
Query: 233 MPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQD 288
+ ++ SF +VP +D + L+ +ML + +RIS++ +L HP+ +D
Sbjct: 903 V--HRNSFRPTPPVPLQTLVPEMDPQAKDLMEKMLVFKSGRRISSRESLLHPYLRD 1064
>32000
Length = 644
Score = 237 bits (605), Expect = 4e-63, Method: Compositional matrix adjust.
Identities = 106/153 (69%), Positives = 129/153 (84%)
Frame = -1
Query: 139 GAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT 198
+K+ADFGLAR FG+PVRTYTHEV+TLWYRAPEILLGC++YS VDIWSLGCIF EM+T
Sbjct: 578 AKMKIADFGLARVFGLPVRTYTHEVITLWYRAPEILLGCRFYSVPVDIWSLGCIFVEMMT 399
Query: 199 RRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDED 258
RRALFPGDSEIDQL+RIFRTLGTPDE VWPGV+ +PDYKP+FPKW ++ VV L +
Sbjct: 398 RRALFPGDSEIDQLYRIFRTLGTPDEKVWPGVSKLPDYKPTFPKWPLKNLETVV-SLSKV 222
Query: 259 GRSLLSQMLHYDPNKRISAKAALAHPFFQDVTK 291
G LL +ML Y+PN+RISA++A+ HP+F D+ +
Sbjct: 221 GLDLLKRMLTYNPNRRISARSAMRHPYFNDMKR 123
>01756
Length = 1858
Score = 232 bits (592), Expect = 1e-61, Method: Compositional matrix adjust.
Identities = 131/305 (42%), Positives = 188/305 (61%), Gaps = 14/305 (4%)
Frame = -3
Query: 4 FQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNI 63
++K+ KIG+GT+G V+KAR K T +VVA+KK+ +D E EG P TA+REI +L+ LNH N+
Sbjct: 1736 YEKLAKIGQGTFGEVFKARCKKTKQVVAMKKVLMDNEKEGFPITALREIKILQLLNHENV 1557
Query: 64 VKLLDVIHTE--------NKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGL 115
V L+++ T+ + YLVFEF DL + ++ LP IK + QL+ GL
Sbjct: 1556 VDLIEICSTKATSANRYKSMFYLVFEFCEHDLAGLLSNMSVV-FNLPEIKEVMKQLMNGL 1380
Query: 116 AFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRT---YTHEVVTLWYRAPE 172
+ H +++LHRD+K N+LI +G +KLADFGLARAF V +R YT+ VVTLWYR PE
Sbjct: 1379 YYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRPPE 1200
Query: 173 ILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTS 232
+LLG + YSTA+D W GCI AEM TR + G +E +QL I + G+ VWPGV
Sbjct: 1199 LLLGDRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQNQLTLITQLCGSITPEVWPGVER 1020
Query: 233 MPDYKP-SFPKWARQDFSKVVPPLDEDG--RSLLSQMLHYDPNKRISAKAALAHPFFQDV 289
+ Y P+ ++ + + +D LL ++L DP KR+++ AL+H FF
Sbjct: 1019 LELYNSLDLPQGNKRKVKERLRYYIKDAYALDLLDKLLALDPGKRVNSDEALSHDFFWMD 840
Query: 290 TKPVP 294
+P+P
Sbjct: 839 PEPLP 825
>01707
Length = 757
Score = 216 bits (549), Expect = 1e-56, Method: Compositional matrix adjust.
Identities = 100/220 (45%), Positives = 150/220 (68%)
Frame = +1
Query: 1 MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH 60
ME ++K+ KIGEG+YGVV+K RNK T ++VA+KK + + A+REI +LK+L H
Sbjct: 61 MEKYEKIGKIGEGSYGVVFKCRNKETSQLVAIKKFVESEDDPLIKKIAMREIRMLKQLKH 240
Query: 61 PNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHS 120
PN+V+L++V + +L+LVF+++ L +D G+P P++K ++Q L + FCH
Sbjct: 241 PNLVRLIEVFRRKKRLHLVFDYVDHTLLNELDRYP-RGLPEPMVKRIIYQTLLAVNFCHQ 417
Query: 121 HRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYY 180
+ +HRD+KP+N+LI +G +KL DFG AR P YT V T WYRAPE+L+G Y
Sbjct: 418 YNTIHRDVKPENILITRQGQVKLCDFGFARILTGPGDEYTDYVATRWYRAPELLVGDTQY 597
Query: 181 STAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLG 220
VD+W++GC+FAE++T +AL+PG S++DQL I +TLG
Sbjct: 598 GPPVDVWAIGCVFAELLTGQALWPGRSDVDQLHLIRKTLG 717
>29581
Length = 1278
Score = 195 bits (496), Expect = 2e-50, Method: Compositional matrix adjust.
Identities = 102/256 (39%), Positives = 150/256 (58%), Gaps = 7/256 (2%)
Frame = -2
Query: 45 PSTAIREISLLKELNHPNIVKLLDVI--HTENKLYLVFEFLHQDLKKFMDASALTGIPLP 102
PS + L L H NIV+L +V+ + + L+LV E+ QDL AS L +P P
Sbjct: 1223 PSVVCVRSTFLLNLRHQNIVQLQEVVVGKSLDSLFLVMEYCEQDL-----ASLLDNMPAP 1059
Query: 103 L----IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRT 158
+K + QLL+GL + H ++HRDLK NLL+ +G +K+ADFGLAR +G P +
Sbjct: 1058 FSESQVKCIVLQLLKGLRYLHEAFIIHRDLKVSNLLMTDKGCVKIADFGLARNYGKPQKP 879
Query: 159 YTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRT 218
T +VVTLWYRAPE+L G K +STA+D+WS GCI E++ + L PG S++ Q+ I
Sbjct: 878 MTPKVVTLWYRAPELLFGSKTHSTAIDMWSAGCILGELLGHKPLMPGRSDLQQIELIMEL 699
Query: 219 LGTPDEVVWPGVTSMPDYKP-SFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISA 277
LGTP++ +WPG + +P ++ + K + P L E G LL+ + Y P KR +A
Sbjct: 698 LGTPNDTIWPGFSQLPAFEQFTLKKQPYNNLRHTFPWLSESGIRLLNGLFMYHPQKRATA 519
Query: 278 KAALAHPFFQDVTKPV 293
+ L H +F++ P
Sbjct: 518 EDCLEHSYFKEQPYPC 471
Score = 33.5 bits (75), Expect = 0.12, Method: Compositional matrix adjust.
Identities = 14/34 (41%), Positives = 23/34 (67%)
Frame = -1
Query: 28 EVVALKKIRLDTETEGVPSTAIREISLLKELNHP 61
E+VALKK+R+ E G+P + +REI++ + P
Sbjct: 1275 EIVALKKMRMTGERYGIPISGLREINIFAQSATP 1174
>04591
Length = 1117
Score = 178 bits (451), Expect = 2e-45, Method: Compositional matrix adjust.
Identities = 104/271 (38%), Positives = 152/271 (56%), Gaps = 16/271 (5%)
Frame = -2
Query: 42 EGVPSTAIREISLLKELNHPNIVKLLDVIHTE--------NKLYLVFEFLHQDLKKFMDA 93
EG P TA+REI +L++L H N+V+L ++ HT+ + YL+FE+ DL ++
Sbjct: 1098 EGFPITALREIKILQQLEHENVVQLQEICHTQAGPYNRYKSTFYLIFEYCDYDLAGLLN- 922
Query: 94 SALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFG 153
+ L K+ + QLL GL + H+ ++LHRD+K N+L+ +G +KLADFGL+R +
Sbjct: 921 NLRVKFSLADKKNLMSQLLNGLFYIHTKQILHRDIKAANILLTRDGVLKLADFGLSRPW- 745
Query: 154 VPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLF 213
V + T+ VVTLWYR PE+LLG + Y +D+W +GCI AEM +R+ L G SE QL
Sbjct: 744 VKSKRLTNRVVTLWYRPPELLLGEREYGPEIDMWGVGCIMAEMWSRKPLMQGRSEQHQLS 565
Query: 214 RIFRTLGTPDEVVWPGVT--------SMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQ 265
I G+ + VWPGVT +P KP K D K +++G L+
Sbjct: 564 LITDLCGSLNAEVWPGVTKLELYGKLDLPQGKPRKVKERMLDLLK-----NKEGAELIDI 400
Query: 266 MLHYDPNKRISAKAALAHPFFQDVTKPVPHL 296
L DP +R++ AL+H FF P P L
Sbjct: 399 FLRLDPGQRMNCDNALSHDFFWVDPLPSPSL 307
>04138
Length = 800
Score = 152 bits (385), Expect = 1e-37, Method: Compositional matrix adjust.
Identities = 84/188 (44%), Positives = 112/188 (59%), Gaps = 10/188 (5%)
Frame = +1
Query: 115 LAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRT---YTHEVVTLWYRAP 171
L + H +++LHRD+K N+LI +G +KLADFGLARAF V +R YT+ VVTLWYR P
Sbjct: 52 LYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRPP 231
Query: 172 EILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVT 231
E+LLG + YSTA+D W GCI AEM TR + G +E +QL I + G+ VWPGVT
Sbjct: 232 ELLLGDRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQNQLTLITQLCGSITPEVWPGVT 411
Query: 232 SMPDYKPSFPKWA-------RQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHP 284
+ Y A R F++++ D G L ++L DP++RISA AL H
Sbjct: 412 QLSMYHQIKGALAAGRKNIIRDRFARILK--DPYGLDLFERLLKMDPSQRISADEALNHD 585
Query: 285 FFQDVTKP 292
FF +P
Sbjct: 586 FFWVGVEP 609
>20559
Length = 430
Score = 112 bits (281), Expect(3) = 1e-30, Method: Compositional matrix adjust.
Identities = 52/80 (65%), Positives = 68/80 (85%)
Frame = -2
Query: 1 MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH 60
M+ ++K+EKIGEGTYG V+KA+N+ T E+VALK++RLD + EGVPS+A+REI LLKEL H
Sbjct: 378 MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKH 199
Query: 61 PNIVKLLDVIHTENKLYLVF 80
NIV+L DV+H+E KL LVF
Sbjct: 198 RNIVRLHDVLHSERKLTLVF 139
Score = 33.5 bits (75), Expect(3) = 1e-30, Method: Compositional matrix adjust.
Identities = 18/38 (47%), Positives = 23/38 (60%)
Frame = -3
Query: 80 FEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAF 117
FE+ QDLKK+ D P +KS+L QLL+GL F
Sbjct: 140 FEYCDQDLKKYFDTCNGEIDP-DTVKSFLHQLLRGLGF 30
Score = 24.3 bits (51), Expect(3) = 1e-30, Method: Compositional matrix adjust.
Identities = 9/14 (64%), Positives = 11/14 (78%)
Frame = -1
Query: 113 QGLAFCHSHRVLHR 126
+ L FCHS+ VLHR
Sbjct: 43 EDLVFCHSNNVLHR 2
>00300
Length = 2318
Score = 113 bits (283), Expect = 8e-26, Method: Compositional matrix adjust.
Identities = 80/291 (27%), Positives = 138/291 (47%), Gaps = 9/291 (3%)
Frame = -1
Query: 4 FQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNI 63
+Q+ KIGEG +G VY A N TGE++ALK+++ EI + + + H N+
Sbjct: 1652 WQRGNKIGEGQFGKVYTAVNMSTGELMALKEMKFQPNDLQQLREMCDEIKIFEGIQHENL 1473
Query: 64 VKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRV 123
VK V ++++ + E+ ++ +A G+P LI+ Y +++ + H + +
Sbjct: 1472 VKYYGVEVHKDEMLMFMEYCDTGT---IEEAAKMGLPEYLIRRYTREIVLAVNHLHENSI 1302
Query: 124 LHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYT------HEVV-TLWYRAPEILLG 176
+HRD+K N+ + + G +KL DFG + V ++++T H +V T Y APE+
Sbjct: 1301 VHRDIKGANIFLTSNGHVKLGDFGCS----VKLKSHTTMPGEFHNLVGTTAYMAPEVFTQ 1134
Query: 177 CKY--YSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMP 234
Y A DIWSLGC+ EM T + + ++D ++I +G
Sbjct: 1133 NDQGGYGRAADIWSLGCVVIEMATGKRPW---HDLDNNYQIMYKVGI------------- 1002
Query: 235 DYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPF 285
+KP+ P L +G+ L ++ +DP +R A L H F
Sbjct: 1001 GHKPAVPD-----------SLSVEGKHFLDLIMCHDPAQRALASQLLDHTF 882
>23319
Length = 2235
Score = 110 bits (274), Expect = 1e-24, Method: Compositional matrix adjust.
Identities = 56/114 (49%), Positives = 76/114 (66%), Gaps = 2/114 (1%)
Frame = +3
Query: 178 KYYSTAVDIWSLGCIFAEMVTR-RALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDY 236
K YST++D+WS GCIFAE+ R LFPG+ + DQL RIF+ LGTP E WPG+T +P+Y
Sbjct: 21 KMYSTSIDMWSAGCIFAELANAGRPLFPGNDDDDQLKRIFKLLGTPTEDQWPGMTQLPNY 200
Query: 237 KPSFPKW-ARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDV 289
+ FP + + +VVP L+ GR LL +L P+ R+SA AL HP+F D+
Sbjct: 201 R-MFPMYHVTTTWQQVVPKLNSKGRDLLQCLLVCCPSDRMSADEALQHPYFADL 359
>13592
Length = 980
Score = 108 bits (271), Expect = 2e-24, Method: Compositional matrix adjust.
Identities = 82/289 (28%), Positives = 138/289 (47%), Gaps = 12/289 (4%)
Frame = +2
Query: 9 KIGEGTYGVVYKARNKLTGEVVALKKIRLD-TETEGVPSTAIREISLLKELNHPNIVKLL 67
KIG+G +G VY A N TGE++A+K+I + ET + + A E+ +L+ + H N+V+
Sbjct: 5 KIGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETRALKNVA-EELKILEGIKHKNLVRYY 181
Query: 68 DV-IHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHR 126
+ +H E L + L+ ++ + G+P L + + QLL G+A H H ++HR
Sbjct: 182 GIEVHREELLIFMELCSEGTLESLVELTG--GLPEALSRRFTAQLLSGVAELHKHGIVHR 355
Query: 127 DLKPQNL-LINTEGAIKLADFGLARAFGVPVRTYT-------HEVVTLWYRAPEIL--LG 176
D+K N+ L++ ++KL DFG A V ++ +T V T Y APE+
Sbjct: 356 DIKTANIFLVDGSNSLKLGDFGSA----VKIQAHTTVPGELQGYVGTQAYMAPEVFTKTN 523
Query: 177 CKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDY 236
+ DIWS+GC+ EM + + + ++ D F+I +G +
Sbjct: 524 SDGHGRLADIWSVGCVVVEMASGKRPW---AQFDSNFQIMFKVGMGE------------- 655
Query: 237 KPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPF 285
KP P+ L ++G + L +DP +R+SA L F
Sbjct: 656 KPQAPE-----------SLSQEGHDFIDHCLQHDPKQRLSAIELLEQNF 769
>18921
Length = 697
Score = 108 bits (270), Expect = 3e-24, Method: Compositional matrix adjust.
Identities = 66/197 (33%), Positives = 110/197 (55%), Gaps = 4/197 (2%)
Frame = +2
Query: 4 FQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNI 63
F + K+GEG+YG V+K+ +K TG+V+A+K++ +DT+ + + I+EIS++++ + I
Sbjct: 35 FDILGKLGEGSYGSVFKSLHKETGQVLAIKQVPVDTDLQEI----IKEISIMQQCDSKYI 202
Query: 64 VKLLDVIHTENKLYLVFEFLH----QDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCH 119
VK L++V E+ D+ + + + + I + L+ L+GL + H
Sbjct: 203 VKYYGSYFKNTDLWIVMEYCGAGSVSDIMRLRNKTLVE----REIATILYYTLKGLXYLH 370
Query: 120 SHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKY 179
S R +HRD+K N+L+N EG KLADFG+A + + T ++ APE++ Y
Sbjct: 371 SRRKIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTPYWMAPEVIQEIGY 550
Query: 180 YSTAVDIWSLGCIFAEM 196
A DIWSLG EM
Sbjct: 551 DCVA-DIWSLGITALEM 598
>03294
Length = 1684
Score = 106 bits (264), Expect = 1e-23, Method: Compositional matrix adjust.
Identities = 52/113 (46%), Positives = 68/113 (60%), Gaps = 3/113 (2%)
Frame = -1
Query: 184 VDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKW 243
VD+WS+G IFA+M+ R +F GDSEIDQLF+IFR +GTP E WP +P + FP W
Sbjct: 1672 VDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKLPAFNGMFPLW 1493
Query: 244 ARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDV---TKPV 293
S+ + LD G L+ + L DP +RIS K L H +F +V KPV
Sbjct: 1492 KEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYFLNVDTSVKPV 1334
>24241
Length = 413
Score = 104 bits (259), Expect = 5e-23, Method: Compositional matrix adjust.
Identities = 56/116 (48%), Positives = 78/116 (67%), Gaps = 1/116 (0%)
Frame = -2
Query: 4 FQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPN- 62
++ KIGEGTYGVVYK R++ TG +A+KKIRL +GVPS+AIREI++L+EL H
Sbjct: 337 LDRLSKIGEGTYGVVYKCRHRATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTQX 158
Query: 63 IVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFC 118
+V L DVI + +L+LVFEFL DLK ++D G+ L L +++ G+ FC
Sbjct: 157 LVCLEDVIMEDERLFLVFEFLSMDLKMYIDKFP-EGVVLD---RRLVKIVTGINFC 2
>06405
Length = 1965
Score = 100 bits (249), Expect = 6e-22, Method: Compositional matrix adjust.
Identities = 73/228 (32%), Positives = 119/228 (52%), Gaps = 11/228 (4%)
Frame = +1
Query: 9 KIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLD 68
++G G YG VY+A K ++VA+K ++ DT + + E +++KE+ HPN+V+LL
Sbjct: 280 RLGGGQYGDVYEAMWKRYNKIVAVKTLKEDTMAL---NDFLEEAAIMKEMKHPNLVQLLG 450
Query: 69 VIHTENKLYLVFEFL-HQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRD 127
V E Y+V EF+ H +L ++ +S + Q+ G+A+ + +HRD
Sbjct: 451 VCTREPPFYIVTEFMPHGNLLDYLRSSTREENGPTALMYMATQIASGMAYLETKNFIHRD 630
Query: 128 LKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEV---VTLWYRAPEILLGCKYYSTAV 184
L +N L+ +K+ADFGLAR TYT + + + APE L +ST
Sbjct: 631 LAARNCLVADSNMVKVADFGLARLMK--DDTYTAHIGAKFPIKWTAPEG-LAFNRFSTRS 801
Query: 185 DIWSLGCIFAEMVT-RRALFPGD--SEIDQL----FRIFRTLGTPDEV 225
DIW+ G + E+ T + +PG +E+ L +R+ R GTP +V
Sbjct: 802 DIWAFGVLLWELATYGMSPYPGVELTEVYHLLERGYRMERPPGTPADV 945
>09606
Length = 1300
Score = 96.3 bits (238), Expect = 1e-20, Method: Compositional matrix adjust.
Identities = 84/310 (27%), Positives = 135/310 (43%), Gaps = 23/310 (7%)
Frame = -3
Query: 1 MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH 60
MENF E++G+G + ++YK R K T VA+ I E + + +++H
Sbjct: 1118 MENFVLYEELGKGEHSIIYKGRRKGTINFVAIHCIEKCKRPE-----VTNTVRMTHDISH 954
Query: 61 PNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTG-IPLPLIKSYLFQLLQGLAFCH 119
PN+V+ + T N L+LV E D A +P I+ + L+ GL + H
Sbjct: 953 PNVVQFHEWYETSNHLWLVVELCTGG--SLADILAQDHHLPETSIRDFGIHLVTGLHYIH 780
Query: 120 SHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTH---EVVTLW--------- 167
S +L DL+P +L++T G +K ADFGL++ G + E W
Sbjct: 779 SLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQWNIQSAEEMM 600
Query: 168 ----------YRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFR 217
Y APE+ G + S D+W+LGC+F EM + F G++ + I
Sbjct: 599 KQVPTSGSPTYMAPEVFQGAE-PSIMSDLWALGCVFYEMFSGHPPFLGET-----YDI-- 444
Query: 218 TLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISA 277
T D+V+ + + PK S P + +LL +L D +R+S
Sbjct: 443 ---TKDKVL--------NKEFPLPKVKGSRLSAKPSP---EFLNLLESLLQKDSTRRLSW 306
Query: 278 KAALAHPFFQ 287
+ + H F+Q
Sbjct: 305 ASLVKHAFWQ 276
>03508
Length = 1463
Score = 95.5 bits (236), Expect = 2e-20, Method: Compositional matrix adjust.
Identities = 62/203 (30%), Positives = 104/203 (51%), Gaps = 4/203 (1%)
Frame = +1
Query: 2 ENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHP 61
+++Q V K+G G Y V++A N E K + + L
Sbjct: 589 DDYQIVRKLGRGKYSEVFEAINVTNNE----KCVIKILKPVKKKKIKREIKILENLRGGT 756
Query: 62 NIVKLLDVIH--TENKLYLVFEFLHQ-DLKKFMDASALTGIPLPLIKSYLFQLLQGLAFC 118
N++ LL ++ L+FE ++ D K+ T I+ YL++L++ L FC
Sbjct: 757 NVITLLAIVKDPVSRTPALIFEHVNNTDFKQLY--QTFTDYD---IRFYLYELMKALDFC 921
Query: 119 HSHRVLHRDLKPQNLLINTEGA-IKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGC 177
HS ++HRD+KP N++I+ E ++L D+GLA F P Y V + +++ PE+LL
Sbjct: 922 HSMGIMHRDVKPHNVMIDHENKKLRLIDWGLAE-FYHPGMEYNVRVASRYFKGPELLLDY 1098
Query: 178 KYYSTAVDIWSLGCIFAEMVTRR 200
+ Y ++D+WSLGC+FA M+ R+
Sbjct: 1099QMYDYSLDMWSLGCMFASMIFRK 1167
Score = 45.1 bits (105), Expect = 4e-05, Method: Compositional matrix adjust.
Identities = 32/119 (26%), Positives = 51/119 (42%), Gaps = 9/119 (7%)
Frame = +2
Query: 177 CKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDY 236
C +W+ C+ A + F G DQL RI + LGT D + + D
Sbjct: 1103 CMTTHWTCGVWA-ACLPA*SSGKSPFFHGHDNYDQLVRIAKVLGTDDLYGYIEKYQI-DL 1276
Query: 237 KPSF---------PKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFF 286
P F +W R S+ + + L ++L YD N+R++A+ A+ HP+F
Sbjct: 1277 DPRFNDILGRHSRKRWERFVHSENQHLISPEALDFLDKLLRYDHNERLTAREAMDHPYF 1453
>12721
Length = 821
Score = 95.5 bits (236), Expect = 2e-20, Method: Compositional matrix adjust.
Identities = 64/213 (30%), Positives = 109/213 (51%), Gaps = 6/213 (2%)
Frame = +1
Query: 9 KIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLD 68
KIGEG+ G+V A ++ G +A+KK +D + E+ ++++ +HPNIV++ +
Sbjct: 109 KIGEGSTGIVCIATSR-DGRQMAVKK--MDLRKQQRRELLFNEVVVMRDYHHPNIVEMYN 279
Query: 69 VIHTENKLYLVFEFLHQDLKKFMDASALTGIPLP------LIKSYLFQLLQGLAFCHSHR 122
++L++V EF M+ ALT I I + L+ LAF H++
Sbjct: 280 SYLVNDELWVVMEF--------MEGGALTDIVTNNRMDEVQIATVCRACLKALAFLHANG 435
Query: 123 VLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYST 182
V+HRD+K ++L++ +G +KL DFG ++ V T ++ APE++ Y
Sbjct: 436 VIHRDIKSDSILLSHDGKVKLXDFGFCAQVTQDLQKRKSLVGTPYWMAPEVISRLP-YGP 612
Query: 183 AVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRI 215
VDIWSLG + EM+ F + + + RI
Sbjct: 613 EVDIWSLGIMVMEMIDAEPPFFNEPPLQAMRRI 711
>19761
Length = 473
Score = 91.3 bits (225), Expect = 4e-19, Method: Compositional matrix adjust.
Identities = 47/125 (37%), Positives = 73/125 (58%), Gaps = 2/125 (1%)
Frame = -3
Query: 98 GIPLPLIKSYLFQLLQGLAFCHSHR--VLHRDLKPQNLLINTEGAIKLADFGLARAFGVP 155
G+P LI +L Q L + H+H +LHRDLKPQN+ + +G ++L D GLAR P
Sbjct: 435 GLPERLIVCWLMQTASALNYMHTHTPVILHRDLKPQNIYVTEKGDVRLGDLGLARKLTGP 256
Query: 156 VRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRI 215
T +V T+ Y +PEI L + Y++ DIWSLGC+F ++ ++ G E+ +F +
Sbjct: 255 ADFATSQVGTIMYLSPEI-LSQQPYNSKSDIWSLGCVFYDITGKK----GSDEMGVMFLL 91
Query: 216 FRTLG 220
+ +G
Sbjct: 90 VQVMG 76
>01718
Length = 959
Score = 91.3 bits (225), Expect = 5e-19, Method: Compositional matrix adjust.
Identities = 66/209 (31%), Positives = 110/209 (52%), Gaps = 6/209 (2%)
Frame = +3
Query: 7 VEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKL 66
EKIG G + V+K +++TG+V+ALK ++T T +RE+ LL L H NI++
Sbjct: 162 CEKIGAGFFSEVFKVTHRITGQVMALK---MNTMTSN-RHNMLREVQLLNRLQHANILRF 329
Query: 67 LDVIHTENKLYLVFEFL-HQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLH 125
+ V E +L+ + E++ +L++ ++ +P L +GL + HS R +H
Sbjct: 330 MGVCVHEGQLHALTEYIPSGNLEQLLEKKD-EELPWTQRIQLTLGLARGLDYLHSTRFIH 506
Query: 126 RDLKPQNLLINTEGA----IKLADFGLARAFGVPV-RTYTHEVVTLWYRAPEILLGCKYY 180
RDL +N+LI E +ADFGLA P+ + V + ++ APE+L G +Y
Sbjct: 507 RDLTSKNILIRREDNHGYHAVIADFGLATKIPDPLDKEKLPTVGSPYWMAPEVLNG-HFY 683
Query: 181 STAVDIWSLGCIFAEMVTRRALFPGDSEI 209
+ D++S+G I E+ R P D +I
Sbjct: 684 NERADLFSVGIIMCEITAR---IPADPDI 761
>14420
Length = 528
Score = 90.1 bits (222), Expect = 9e-19, Method: Compositional matrix adjust.
Identities = 52/149 (34%), Positives = 78/149 (52%)
Frame = +2
Query: 49 IREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYL 108
I EI +++E +PNIV LD +L++V EFL D T + I +
Sbjct: 44 INEILVMRENQNPNIVNYLDSYLVGEELWVVMEFLAGG--SLTDVVTETCMDEGQIAAVC 217
Query: 109 FQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWY 168
+ LQ L F H ++V+HRD+K N+L+ +G++KL DFG + V T ++
Sbjct: 218 RECLQALEFLHENQVIHRDIKSDNILLGMDGSVKLTDFGFCAQLSPEQSKRSTMVGTPYW 397
Query: 169 RAPEILLGCKYYSTAVDIWSLGCIFAEMV 197
APE++ K Y VDIWSLG + EM+
Sbjct: 398 MAPEVVTR-KQYGPTVDIWSLGVMCIEMI 481
>17975
Length = 449
Score = 85.1 bits (209), Expect = 3e-17, Method: Compositional matrix adjust.
Identities = 50/137 (36%), Positives = 80/137 (58%), Gaps = 2/137 (1%)
Frame = +3
Query: 15 YGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTEN 74
+ VV AR+ TGE VA+K I E S +E+ +K + HPN+V+L +VI T+
Sbjct: 6 FAVVKLARHVFTGEKVAVKVIDKTKLDEVSRSHLFQEVRCMKLVQHPNVVRLYEVIDTQT 185
Query: 75 KLYLVFEFLH-QDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNL 133
KLYL+ E D+ ++ + G+ L K Y Q+++ +++CH V+HRDLKP+N+
Sbjct: 186 KLYLILELGDGGDMYDYIMRHS-GGLEEKLAKRYFRQIVEAISYCHKLHVVHRDLKPENV 362
Query: 134 LINTE-GAIKLADFGLA 149
+ + G +KL DFG +
Sbjct: 363 VFFEKPGLVKLTDFGFS 413
>12453
Length = 680
Score = 82.8 bits (203), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 41/102 (40%), Positives = 58/102 (56%), Gaps = 1/102 (0%)
Frame = +3
Query: 189 LGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKP-SFPKWARQD 247
+GCIF EM R LFPG + D+L IF+TLGTP E P ++ PD+ + P + +
Sbjct: 6 VGCIFYEMACGRPLFPGSTVEDELHLIFKTLGTPTEDSLPSISRNPDFLALNLPHYQGEA 185
Query: 248 FSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDV 289
+ P LD DG LL++ L Y+ R+SA +L H FF +
Sbjct: 186 LITIAPRLDSDGLDLLAKFLKYNAKIRVSAADSLKHSFFNSL 311
>13066
Length = 551
Score = 80.1 bits (196), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 56/185 (30%), Positives = 89/185 (48%), Gaps = 7/185 (3%)
Frame = +3
Query: 13 GTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHT 72
GT+ Y KL +++ +K +D + P RE+ LL +L+HP I+++ ++
Sbjct: 24 GTFNDGYGRNIKLACKIIDKEKAPVDFVEKFFP----RELDLLTKLDHPYIIQIHSILQR 191
Query: 73 ENKLYLVFEFLHQ-DLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQ 131
K ++ F + DL ++ + K + +Q+ L + HS+ V HRDLK +
Sbjct: 192 XPKNFIFMRFAERGDLLTYIQEVGF--VKEKQAKIWFYQMTTALNYLHSYDVAHRDLKCE 365
Query: 132 NLLINTEGAIKLADFGLARAFGVP------VRTYTHEVVTLWYRAPEILLGCKYYSTAVD 185
N+L+++ +KLADFG A A RTY Y APEI+ G Y D
Sbjct: 366 NILLSSHFNVKLADFGFACACITESGEKYMSRTYCGSAA---YAAPEIVYGAPYAPKVAD 536
Query: 186 IWSLG 190
WSLG
Sbjct: 537 AWSLG 551
>15910
Length = 1361
Score = 79.3 bits (194), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 55/192 (28%), Positives = 94/192 (48%), Gaps = 3/192 (1%)
Frame = +2
Query: 110 QLLQGLAFCHSHRVLHRDLKPQNLL---INTEGAIKLADFGLARAFGVPVRTYTHEVVTL 166
+L G+ + H++ V+HRDLKP+NLL + + +KLADFGL+R V+ T T
Sbjct: 488 DILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLADFGLSRIIEPEVQMSTV-CGTP 664
Query: 167 WYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVV 226
Y APE+L G K Y+ +VD+WS+G I ++ F ++E + +I + DE
Sbjct: 665 GYCAPEVLKGDK-YTPSVDMWSVGVIAYILLCGYEPFFAENEFEMYRKIIKGEYKFDEEY 841
Query: 227 WPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFF 286
W ++ E+ + ++ ++L DP KR++A AL P+
Sbjct: 842 WSEIS-------------------------ENAKDVVRKLLVIDPKKRLTATEALRLPWV 946
Query: 287 QDVTKPVPHLRL 298
+ V ++ +
Sbjct: 947 KGVATKTTNMEI 982
>03240
Length = 1683
Score = 77.8 bits (190), Expect = 4e-15, Method: Compositional matrix adjust.
Identities = 67/259 (25%), Positives = 107/259 (41%), Gaps = 46/259 (17%)
Frame = -3
Query: 4 FQKVEKIGEGTYGVVYKARNKLTGEVVALKKIR-LDTETEGVPSTAIREISLLKELNHPN 62
F+K++ +G G +G V R TG + A+K +R D + E +L E ++
Sbjct: 1285 FEKIKTLGVGAFGEVSLCRKNDTGMLYAMKTLRKSDVLKRNQVAHVKAERDILAEADNEW 1106
Query: 63 IVKLLDVIHTENKLYLVFEFL-HQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSH 121
+VKL N LY V +++ DL + + + PL + Y+ +L+Q + H
Sbjct: 1105 VVKLYYSFQDHNYLYFVMDYVPGGDLMGLLIRMEI--LDEPLARFYVAELVQAIESVHRM 932
Query: 122 RVLHRDLKPQNLLINTEGAIKLADFGLARAF------------GVPVRTYTHEVV----- 164
+HRD+KP N+LI+ G IKL DFGL F G R + EV
Sbjct: 931 GFIHRDIKPDNILIDRNGHIKLTDFGLCTGFRWTHNSKYYQRDGTHARQDSMEVKCQLDE 752
Query: 165 ---------------------------TLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMV 197
T Y APE+L Y++ D WS+G I EM+
Sbjct: 751 QCQCEILKPLERRRKREQRCLAHSLVGTPNYIAPEVLSRLGGYTSVCDWWSVGVILFEML 572
Query: 198 TRRALFPGDSEIDQLFRIF 216
F ++ + +++
Sbjct: 571 VGHPPFYANTPAETQYKVI 515
>19301
Length = 712
Score = 74.3 bits (181), Expect = 6e-14, Method: Compositional matrix adjust.
Identities = 47/150 (31%), Positives = 75/150 (50%), Gaps = 2/150 (1%)
Frame = +2
Query: 2 ENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHP 61
E+ +E +G G G V+ KL E VA+KK+R ET+ I L++LNHP
Sbjct: 305 ESITDLEWLGSGAQGAVFLG--KLCAEEVAVKKVRDIKETD---------IRNLRKLNHP 451
Query: 62 NIVKLLDVIHTENKLYLVFEFL--HQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCH 119
NI+ V ++ E+ Q + D IP L+ + Q+ G+ + H
Sbjct: 452 NIISFKGVCTQAPCYCIIMEYCPYGQLYEVLRDGKE---IPPALVLDWSKQIASGMNYLH 622
Query: 120 SHRVLHRDLKPQNLLINTEGAIKLADFGLA 149
SH+++HRDLK N+L+ +K++DFG +
Sbjct: 623 SHKIIHRDLKSPNVLVAKNDVVKISDFGTS 712
>21808
Length = 1011
Score = 73.9 bits (180), Expect = 8e-14, Method: Compositional matrix adjust.
Identities = 51/191 (26%), Positives = 95/191 (49%), Gaps = 5/191 (2%)
Frame = +1
Query: 30 VALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFL-HQDLK 88
VA+K ++ T P + E ++K+L HP +++L V ++ ++++ E + + L
Sbjct: 28 VAIKTLKSGTMD---PKDFLAEAQIMKKLRHPKLIQLYAVCTQDDPIFIITELMKNGSLL 198
Query: 89 KFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGL 148
+F+ + LP + Q+ G+A+ S +HRDL +N+L++ +K+ADFGL
Sbjct: 199 EFLQGKGRV-LKLPALIDIGAQIACGMAYLESQNYIHRDLAARNILVSDNNTVKIADFGL 375
Query: 149 ARAFGVPVRTYTHEVVTLW---YRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-RRALFP 204
AR + Y V + + APE ++ D+WS G + E VT R +P
Sbjct: 376 ARV--IKEDEYEARVGARFPIKWTAPEA-ANYNRFTIKSDVWSFGILLTETVTYGRVPYP 546
Query: 205 GDSEIDQLFRI 215
G + + L ++
Sbjct: 547 GMTNAEVLHQV 579
>18484
Length = 635
Score = 73.2 bits (178), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 52/178 (29%), Positives = 85/178 (47%)
Frame = +1
Query: 102 PLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTH 161
P+ Y ++ GL F H +++RDLK N+++++EG IK+ADFG+ + T
Sbjct: 43 PVAAFYAAEIAVGLFFLHDQGIIYRDLKLDNVMLDSEGHIKIADFGMCKEGMTGDATTRT 222
Query: 162 EVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGT 221
T Y APEI+L + YS +VD W+ G + EM+ + F G+ E D+LF
Sbjct: 223 FCGTPDYIAPEIVL-YQPYSKSVDWWAYGVLLFEMLAGQPPFDGEDE-DELF-------- 372
Query: 222 PDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKA 279
+S+ D+ S+PK + + SL +L +P KR+ +
Sbjct: 373 ---------SSITDHNVSYPK-----------AMSREAVSLCKGLLMKNPTKRLGCGS 486
>30755
Length = 1137
Score = 72.8 bits (177), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 59/189 (31%), Positives = 87/189 (46%), Gaps = 5/189 (2%)
Frame = +2
Query: 107 YLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTL 166
Y +++ L + HS +++RDLK +NLL++ +G IK+ADFGL + RT T
Sbjct: 47 YGAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCKEDITYGRTTKTFCGTP 226
Query: 167 WYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVV 226
Y APE+L Y AVD W G + EM+ R F + + D LF TL ++V
Sbjct: 227 EYLAPEVLDDND-YGRAVDWWGTGVVMYEMICGRLPF-YNRDHDVLF----TLILVEDV- 385
Query: 227 WPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISA-----KAAL 281
FP+ + ++ +SLLS +L DP R+ K
Sbjct: 386 ------------KFPR-----------NITDEAKSLLSGLLAKDPRNRLGGGQDDVKEIQ 496
Query: 282 AHPFFQDVT 290
AHPFF +
Sbjct: 497 AHPFFASIN 523
>21433
Length = 590
Score = 60.5 bits (145), Expect(2) = 3e-13, Method: Compositional matrix adjust.
Identities = 37/91 (40%), Positives = 55/91 (60%)
Frame = +2
Query: 107 YLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTL 166
Y++QL L +CH +V+HRD+KP+NLL+ +G +K+ADFG + P T TL
Sbjct: 182 YIYQLSSALEYCHYRKVIHRDIKPENLLLGLKGDLKIADFGW--SVHAPSSRRTTMCGTL 355
Query: 167 WYRAPEILLGCKYYSTAVDIWSLGCIFAEMV 197
Y PE++ G K + VD+WSLG + E +
Sbjct: 356 DYLPPEMVEG-KTHDENVDLWSLGVLCYEFL 445
Score = 32.0 bits (71), Expect(2) = 3e-13, Method: Compositional matrix adjust.
Identities = 12/33 (36%), Positives = 20/33 (60%)
Frame = +3
Query: 50 REISLLKELNHPNIVKLLDVIHTENKLYLVFEF 82
REI + L H NI+++ H + ++YL+ EF
Sbjct: 15 REIEIQSHLRHDNILRMFGYFHDKTRVYLILEF 113
>11780
Length = 1713
Score = 70.9 bits (172), Expect = 6e-13, Method: Compositional matrix adjust.
Identities = 45/147 (30%), Positives = 86/147 (58%), Gaps = 1/147 (0%)
Frame = +3
Query: 8 EKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLL 67
E IG+G +G VYK + G+ VA+K+++ E + ++E S++ L H N+V+L+
Sbjct: 615 EAIGKGDFGDVYKGMYR--GQPVAIKQLKDKDRGE---QSFLQEASVMTSLRHDNLVRLI 779
Query: 68 DVIHTENKLYLVFEFLHQ-DLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHR 126
V+ E ++LV EF+ + +L +++ + + I ++ + + S R++HR
Sbjct: 780 GVVLGET-IFLVTEFMGKGNLVEYLRSRGRSVITKKDQINFATDTCAAMEYLESKRLVHR 956
Query: 127 DLKPQNLLINTEGAIKLADFGLARAFG 153
DL +N+L++ +G K++DFGLA+ FG
Sbjct: 957 DLAARNVLVHDDGKAKVSDFGLAK-FG 1034
>04852
Length = 1462
Score = 70.1 bits (170), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 53/198 (26%), Positives = 95/198 (47%), Gaps = 28/198 (14%)
Frame = +1
Query: 29 VVALKKIRLDTETEGVPSTAIREISLLKEL----NHPNIVKLLDVIHTENKLYLVFEFL- 83
VA+K +R D T ++E+ ++K + +H NIV L L+++ EF
Sbjct: 25 TVAVKMLR-DIVTAVEEQDFVQELQVMKAVKKMGSHINIVNFLGCCTQGGPLWVIVEFAK 201
Query: 84 HQDLKKFMDAS--ALTG---------------------IPLPLIKSYLFQLLQGLAFCHS 120
+ +L+ F+++ + G I + SY FQ+ +G+ F S
Sbjct: 202 NGNLRDFLESCRDGINGYGKFVSPQDPGWYTKTPGGHVIRRKNLLSYAFQIARGMEFLAS 381
Query: 121 HRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYY 180
+ +HRDL +N+L+ E +K+ADFGL+R G + + + + + APE L + Y
Sbjct: 382 RKCIHRDLAARNVLVTEEHVLKIADFGLSRT-GDYYKKRSGGRLPVKWMAPEALFDMR-Y 555
Query: 181 STAVDIWSLGCIFAEMVT 198
+T D+WS G + E+ +
Sbjct: 556 TTKSDVWSFGVVLWEIFS 609
>28638
Length = 1458
Score = 70.1 bits (170), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 42/107 (39%), Positives = 61/107 (57%), Gaps = 4/107 (3%)
Frame = -1
Query: 96 LTGIPLPLIKSYLFQLLQGLAFCHS--HRVLHRDLKPQNLLINT--EGAIKLADFGLARA 151
L G+ L L + + QL L F + ++H DLKP+N+L+ AIK+ DFG +
Sbjct: 855 LEGVSLNLTRKFAQQLCTALLFLATPEMNIIHCDLKPENILLCNPKRSAIKIVDFGSSCQ 676
Query: 152 FGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT 198
G + Y + + +YR+PE+LLG Y A+D+WSLGCI EM T
Sbjct: 675 LGQRIYQY---IQSRFYRSPEVLLGVPY-DLAIDMWSLGCILVEMHT 547
Score = 30.4 bits (67), Expect = 0.81, Method: Compositional matrix adjust.
Identities = 37/156 (23%), Positives = 52/156 (33%), Gaps = 43/156 (27%)
Frame = -2
Query: 178 KYYSTAVDIWSLGC-----IFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTS 232
+ Y W L C + LF G +E DQ+ +I LG P +
Sbjct: 623 RCYXXCPMTWPLTCGXWAVYWWRCTXGNPLFAGSNEFDQMMKIVEVLGVPPRHILDQAQK 444
Query: 233 -------MPD--YKPSFPKWARQDFSKVVPP--------------------LDEDG---- 259
+PD Y P P+ D K P + E G
Sbjct: 443 TRKYFDLLPDGTYAPKKPR----DNKKYKSPSSRKLHEVLGAEKGGPGGRRMGEPGHTVA 276
Query: 260 -----RSLLSQMLHYDPNKRISAKAALAHPFFQDVT 290
+ L+ +ML +DP RIS AL H FF+ +
Sbjct: 275 DYLKFKDLILRMLDFDPKTRISPYYALQHNFFRKTS 168
>09007
Length = 1440
Score = 69.7 bits (169), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 51/206 (24%), Positives = 101/206 (49%), Gaps = 15/206 (7%)
Frame = -1
Query: 8 EKIGEGTYGVVYKA------RNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHP 61
+ +G+G +G V +A K+ V L K ++ + + ++E ++++ L+H
Sbjct: 861 KSLGQGHFGTVRQAIWTAESGEKVQVAVKCLSKDKIHKDGQEF----LKETAIMQMLDHE 694
Query: 62 NIVKLLDVIHTENK-LYLVFEF--LHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFC 118
NIV++ V+ + LV E + L+ + SA +P + + Q+ G+++
Sbjct: 693 NIVRVYGVVMDNGADIMLVTELAPMRSLLECVKEVSARVDFSVPRLCDFSQQVCDGMSYL 514
Query: 119 HSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYT-----HEVVTLWYRAPEI 173
S R++HRDL +N+L+ ++ +K++D G++ A G Y H + + APE
Sbjct: 513 ESKRLVHRDLAARNILLFSKSKVKISDVGVSGALGAGKEYYQSQQTIHLQNAVAWCAPES 334
Query: 174 LLG-CKYYSTAVDIWSLGCIFAEMVT 198
C +S+A D+W+ G + E T
Sbjct: 333 FRNLC--FSSASDVWAFGVLLWEFFT 262
>00392
Length = 668
Score = 69.3 bits (168), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 56/199 (28%), Positives = 97/199 (48%), Gaps = 14/199 (7%)
Frame = +3
Query: 51 EISLLKELNHPNIVKLLDVIHTENK-----LYLVFEFLHQD-----LKKFMDASALTGIP 100
E +LKEL HPNIV+ D N + LV E + LK+F +
Sbjct: 81 EAEMLKELQHPNIVRFFDYWEEHNHRNRKVIILVTELMTSGTLKTYLKRFKKPN------ 242
Query: 101 LPLIKSYLFQLLQGLAFCHSHR--VLHRDLKPQNLLINT-EGAIKLADFGLARAFGVPVR 157
+ ++K++ Q+L+GL F H+ V+HRDLK N+ I G++K+ D GLA + +
Sbjct: 243 VKILKNWCRQVLKGLYFLHTRTPPVIHRDLKCDNIFITGPTGSVKIGDLGLA---TLKNQ 413
Query: 158 TYTHEVV-TLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIF 216
++ V+ T + APE+ ++Y AVD+++ G EM + + S Q+++
Sbjct: 414 SFAKSVIGTPEFMAPEMYE--EHYDEAVDVYAFGMCMLEMASSEYPYSECSNAAQIYKRV 587
Query: 217 RTLGTPDEVVWPGVTSMPD 235
+ P+ + +T + D
Sbjct: 588 TSGVLPEALDKVAITEIRD 644
>32359
Length = 928
Score = 60.5 bits (145), Expect(2) = 2e-12, Method: Compositional matrix adjust.
Identities = 39/120 (32%), Positives = 67/120 (55%), Gaps = 8/120 (6%)
Frame = -1
Query: 10 IGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDV 69
IG G++GVVY+A+ T E+VA+KK+ D + RE+ ++++L H NIVKL
Sbjct: 406 IGNGSFGVVYQAKLVDTSELVAIKKVLQDKRFKN------RELQIMRKLEHQNIVKLKFF 245
Query: 70 IHTENK------LYLVFEFLHQDLKKFMD--ASALTGIPLPLIKSYLFQLLQGLAFCHSH 121
++ + L LV E++ + + + + + IP+ IK Y++QL + LA+ HS
Sbjct: 244 FYSSGEKKDEVFLNLVLEYVPETVYRVARHYSKSKQTIPILYIKLYMYQLFRSLAYIHSQ 65
Score = 28.9 bits (63), Expect(2) = 2e-12, Method: Compositional matrix adjust.
Identities = 11/19 (57%), Positives = 15/19 (78%)
Frame = -3
Query: 123 VLHRDLKPQNLLINTEGAI 141
V HRD+KPQNLL++ E +
Sbjct: 62 VCHRDIKPQNLLLDPETGV 6
>18287
Length = 678
Score = 69.3 bits (168), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 43/131 (32%), Positives = 64/131 (48%), Gaps = 15/131 (11%)
Frame = -3
Query: 179 YYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPD----EVVWPGVTSMP 234
+Y ++DIWS+GCIFAE+++RR LF + QL I +GTP E G +
Sbjct: 676 HYDYSIDIWSVGCIFAELLSRRILFQAQGPVQQLDMIINLVGTPRPEDMERACEGARNHI 497
Query: 235 DYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQD------ 288
+P F + + P + LL++ML +P RISA+ AL+HP+ +
Sbjct: 496 LNQP-FRRQNLLTLYNLSPHATHEAVRLLTRMLILNPKNRISAEEALSHPYLDEGRVRFH 320
Query: 289 -----VTKPVP 294
KPVP
Sbjct: 319 SCMCSCCKPVP 287
>19094
Length = 898
Score = 69.3 bits (168), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 38/93 (40%), Positives = 53/93 (56%)
Frame = +1
Query: 104 IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEV 163
I + L+ L+GL + HS R +HRD+K N+L+N EG KLADFG+A + +
Sbjct: 64 IATILYYTLKGL*YLHSRRKIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVI 243
Query: 164 VTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEM 196
T ++ APE++ Y A DIWSLG EM
Sbjct: 244 GTPYWMAPEVIQEIGYDCVA-DIWSLGITALEM 339
>13212
Length = 1067
Score = 66.2 bits (160), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 53/188 (28%), Positives = 83/188 (44%), Gaps = 7/188 (3%)
Frame = -1
Query: 110 QLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYR 169
++ L F H H V+HRD+K N+L+ +G +KLADFG++ + + T ++
Sbjct: 956 EMCMALDFLHRHHVIHRDIKAGNVLLTIDGEVKLADFGVSAKNTQTQQKRDTFIGTPYWM 777
Query: 170 APEILLGCKY-----YSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDE 224
APE++L C+ Y DIWSLG E + P + E+ + R+ + D
Sbjct: 776 APEVVL-CETLKDTPYDFKADIWSLGVTLIEFA---QIEPPNKEMHPM-RVLIKIHKSD- 615
Query: 225 VVWPGVTSMPDYKPSFPKWAR--QDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALA 282
P P KW + +DF +++ L DPN R +A L
Sbjct: 614 ---PPTLEKPK------KWTKLFKDF--------------IAKCLVKDPNLRPTAAELLE 504
Query: 283 HPFFQDVT 290
HPF + T
Sbjct: 503 HPFMKRAT 480
>31885
Length = 529
Score = 65.9 bits (159), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 48/157 (30%), Positives = 74/157 (47%), Gaps = 5/157 (3%)
Frame = -2
Query: 52 ISLLKELNHPNIVKLLDVIHTENKLYLVFE-FLHQDLKKFMDASALTGIPLPLIKSYLFQ 110
+ +L L+HP +V L E L++V + FL DL+ M +K YL Q
Sbjct: 519 VDMLTRLDHPFLVNLWYAFQDEEDLFMVVDLFLGGDLRYHMQQEV--SFREDCVKFYLCQ 346
Query: 111 LLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRA 170
L L + S +++HRD+KP N+L++ +G + DF +A T T Y A
Sbjct: 345 LALVLDYLRSQKIVHRDIKPDNILLDEQGHCHVTDFNIATQLE-DDELATSTSGTRPYMA 169
Query: 171 PEI----LLGCKYYSTAVDIWSLGCIFAEMVTRRALF 203
PE+ + + Y VD WSLG E++ +R F
Sbjct: 168 PEVYGVAINERRGYGFPVDWWSLGVSLFELLKKRRPF 58
>27546
Length = 426
Score = 65.1 bits (157), Expect = 3e-11, Method: Compositional matrix adjust.
Identities = 33/102 (32%), Positives = 58/102 (56%), Gaps = 1/102 (0%)
Frame = -1
Query: 50 REISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTG-IPLPLIKSYL 108
RE+ +L L+HPNI+++ ++ K+++ + + + TG I K +
Sbjct: 333 RELEILTRLDHPNIIQIHSILQRGPKIFIFMRYAEKG--DMLSHIKKTGPIDEAQTKVWF 160
Query: 109 FQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLAR 150
FQ+ + L + HSH + HRDLK +N+L++ +K+ADFG AR
Sbjct: 159 FQMAKALQYLHSHDIAHRDLKCENILLSKRLNVKIADFGFAR 34
>26560
Length = 398
Score = 65.1 bits (157), Expect = 3e-11, Method: Compositional matrix adjust.
Identities = 36/113 (31%), Positives = 65/113 (57%), Gaps = 4/113 (3%)
Frame = -1
Query: 104 IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEV 163
++ Y +++ GL HS V++RDLKP N+L++ G ++++D GLA F R + V
Sbjct: 350 VRFYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGLACDFS-KKRPHA-SV 177
Query: 164 VTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALF----PGDSEIDQL 212
T Y APE+L+ + Y ++ D +S GC+ +++ + F G + ID++
Sbjct: 176 GTHGYMAPEVLMKGQSYDSSADWFSFGCMLYKLLKGHSPFRQHNQGQARIDRM 18
>14477
Length = 493
Score = 63.2 bits (152), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 44/154 (28%), Positives = 81/154 (52%), Gaps = 3/154 (1%)
Frame = -1
Query: 9 KIGEGTYGVVYKARNKLTGEV--VALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKL 66
K+G G +G V K +L VA+K ++ V S I+E ++K+++H +IV+L
Sbjct: 469 KLGAGNFGSVMKGVCRLDDREIPVAIKVLKNADLDPSVQSELIKEAEVMKKMDHMHIVRL 290
Query: 67 LDVIHTENKLYLVFEFLHQD-LKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLH 125
+ + E + LV E L KF+ + +PL I ++Q+ QG+ + +++ +H
Sbjct: 289 IGLCEGET-MMLVLELAKLGPLNKFLPKN--KHLPLWNILELMWQVSQGMEYLEANKFVH 119
Query: 126 RDLKPQNLLINTEGAIKLADFGLARAFGVPVRTY 159
RDL +N+L+ E K++DFG+++ Y
Sbjct: 118 RDLAARNILLCDEHFAKISDFGMSKTLSRENNYY 17
>27405
Length = 532
Score = 62.0 bits (149), Expect = 3e-10, Method: Compositional matrix adjust.
Identities = 48/177 (27%), Positives = 88/177 (49%), Gaps = 6/177 (3%)
Frame = -3
Query: 15 YGVVYKARNKLTGEVVALKKI-RLDTETEGVPSTAIREISLLKELN----HPNIVKLLDV 69
+G VY R TG++ A+K + + + +G + A+ E +L ++ P IV +
Sbjct: 527 FGEVYGCRKADTGKMYAMKCLDKKRIKMKGGETLALNERIMLSLVSTGEGSPFIVCMTYA 348
Query: 70 IHTENKLYLVFEFLHQ-DLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDL 128
T KL + + ++ DL + + ++ Y +++ GL HS V++RDL
Sbjct: 347 FQTPEKLCFILDLMNGGDLHYHLSQHGV--FTEKEVRFYAAEVMLGLEHMHSRFVVYRDL 174
Query: 129 KPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVD 185
KP N+L++ G ++++D GLA F + V T Y APE+L+ + Y ++ D
Sbjct: 173 KPANILLDENGHVRISDLGLACDF--SKKKPHASVGTHGYMAPEVLMKGQAYDSSAD 9
>14116
Length = 1017
Score = 61.2 bits (147), Expect = 5e-10, Method: Compositional matrix adjust.
Identities = 52/206 (25%), Positives = 101/206 (49%), Gaps = 14/206 (6%)
Frame = -1
Query: 8 EKIGEGTYGVVYKARNKL---TGEV-VALKKIRLDTETEGVPSTAIREISLLKELNHPNI 63
E+IG+G +G V + L G++ VA+K + + E + ++E ++K+ +H N+
Sbjct: 618 EEIGKGNFGCVKRGFLTLPEQKGDILVAVKTLHNNNPREIELQSFLQEALIMKDFHHSNV 439
Query: 64 VKLLDV-IHTENKLYLVFEFL-HQDLKKFMDASALTGIPLPLIKS---YLFQLLQGLAFC 118
+ L+ + ++ ++ +V F+ H DL ++ P IK Y + +G+ +
Sbjct: 438 LTLIGICLNLDDMPLVVLPFMKHGDLLTYIRDDQHQ----PTIKDLIMYGVDIARGMDYL 271
Query: 119 HSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHE-----VVTLWYRAPEI 173
+ +HRDL +N +++ + +K+ADFGLAR Y+ E + W +
Sbjct: 270 AGLKFVHRDLAARNCMLDEDFHVKVADFGLARDI-YEKEYYSSENKKAKLPVKWMALESL 94
Query: 174 LLGCKYYSTAVDIWSLGCIFAEMVTR 199
G Y + D+WS G + E++TR
Sbjct: 93 EKG--NYDSKTDVWSYGVVLWELLTR 22
>07940
Length = 1336
Score = 60.8 bits (146), Expect = 6e-10, Method: Compositional matrix adjust.
Identities = 38/102 (37%), Positives = 56/102 (54%), Gaps = 3/102 (2%)
Frame = -3
Query: 100 PLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLAR---AFGVPV 156
P LI SY +Q+ +G+ + S + +HRDL +N+L+ E +K+ADFGL R F
Sbjct: 350 PKDLI-SYAYQVARGMEYLASKQCIHRDLAARNVLVAEEYVLKIADFGLTRNLQQFDYYR 174
Query: 157 RTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT 198
+T + W APE L KY S + D+WS G + E+ T
Sbjct: 173 KTTDGRLPVKWM-APEALFDRKYTSKS-DVWSYGVLLWEIFT 54
>16003
Length = 926
Score = 60.5 bits (145), Expect = 9e-10, Method: Compositional matrix adjust.
Identities = 38/99 (38%), Positives = 55/99 (55%)
Frame = -1
Query: 196 MVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPL 255
++ R PGD+++DQL +IF LGTP E WP VTS+PDY F +Q ++
Sbjct: 926 LLIRLPFLPGDTDLDQLGKIFNMLGTPTETEWPAVTSLPDYI-QFKHCQKQPLKEIFTAA 750
Query: 256 DEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP 294
+D LL ++L +P R +A AL P+F + KP P
Sbjct: 749 GDDLLELLDKLLAMNPLHRCTATQALKMPYFSN--KPYP 639
>11185
Length = 473
Score = 59.7 bits (143), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 37/121 (30%), Positives = 56/121 (46%), Gaps = 22/121 (18%)
Frame = +1
Query: 104 IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTH-- 161
I+ + L+ GL + HS +L DL+P +L++T G +K ADFGL++ G +
Sbjct: 7 IRDFGIHLVTGLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKF 186
Query: 162 -EVVTLW-------------------YRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRA 201
E W Y APE+ G + S D+W+LGC+F EM +
Sbjct: 187 AEAGDQWNIQSAEEMMKQVPTSGSPTYMAPEVFQGAE-PSIMSDLWALGCVFYEMFSGSR 363
Query: 202 L 202
L
Sbjct: 364 L 366
>26711
Length = 405
Score = 58.9 bits (141), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 37/105 (35%), Positives = 59/105 (56%), Gaps = 2/105 (1%)
Frame = -2
Query: 110 QLLQGLAFCHSHRVLHRDLKPQNLLINTE--GAIKLADFGLARAFGVPVRTYTHEVVTLW 167
Q+L L H+ V+H DLKP NLL++ + +++L DFGLAR P T+ + T
Sbjct: 392 QVLDILQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARKLYPPQETFLNH-GTPG 216
Query: 168 YRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQL 212
+ +PE L K STA D+W +G + +++ ++ F DS + L
Sbjct: 215 FTSPEA-LDVKPISTASDVWGVGVLAYILLSGQSPFQADSATESL 84
>01106
Length = 878
Score = 58.9 bits (141), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 42/145 (28%), Positives = 74/145 (51%), Gaps = 13/145 (8%)
Frame = +3
Query: 4 FQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNI 63
+ + K+G G + V+ + VALK ++ + TA+ E+ LLK + ++
Sbjct: 324 YHVIRKLGWGHFSTVWLCWDLTCKRFVALKVVK---SAQHYTETALDEVKLLKCVRESDV 494
Query: 64 --------VKLLDVIHTEN----KLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQL 111
V+LLD + +VFE L +L K + S GIP+ +K + Q+
Sbjct: 495 ADPARAKCVQLLDDFKISGVNGTHVAMVFEVLGYNLLKLIIRSNYQGIPIHNVKLIIRQV 674
Query: 112 LQGLAFCHSH-RVLHRDLKPQNLLI 135
L+GL++ H+ R++H D+KP+N+LI
Sbjct: 675 LEGLSYMHAKCRIIHTDIKPENILI 749
>17253
Length = 483
Score = 58.5 bits (140), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 36/132 (27%), Positives = 66/132 (50%), Gaps = 12/132 (9%)
Frame = -1
Query: 34 KIRLDTETEGVPSTAIREISLLKEL-NHPNIVKLLDVIHTENKLYLVFEFL-HQDLKKFM 91
K + T+ S +RE+S++++L HPN+V + + ++ EF H DL F+
Sbjct: 450 KTHNEAATDAEKSEFLRELSIMRKLPRHPNVVSFMGCCTMSDPALILMEFCCHGDLLSFL 271
Query: 92 DASA------LTGIPLPLIK----SYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAI 141
LT L S+ + +G+A +++++HRD+ +N+LI+
Sbjct: 270 RKRRPDRTVFLTSTANDLTARDFFSFALHVARGMAHVANNKIVHRDVAARNVLISERNVC 91
Query: 142 KLADFGLARAFG 153
K++DFGL+R G
Sbjct: 90 KVSDFGLSRRVG 55
>00715
Length = 1788
Score = 57.0 bits (136), Expect = 8e-09, Method: Compositional matrix adjust.
Identities = 52/181 (28%), Positives = 86/181 (47%), Gaps = 33/181 (18%)
Frame = +1
Query: 58 LNHPNIVKLLDV--IHT-ENKLYLVFEFLH--------QDLKKFMDASALTGIPLPLIKS 106
L H N+V +L +H E+ +L E++ D ++ +D+S + L
Sbjct: 97 LRHVNVVSILGATSLHRFEDGAWLAMEYVGPLNLQTILNDHQQDIDSSMRLSLAL----- 261
Query: 107 YLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLA------------RAFGV 154
Q+ +GL + HS ++H DLKP N L+ + +++ADFG R G+
Sbjct: 262 ---QMARGLHYLHSINIVHLDLKPANCLLTRDLKLRIADFGCCHQLTPTGLDMGEREGGM 432
Query: 155 --------PVR-TYTHEVV-TLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFP 204
PV+ + +E+ TL YRAPE+L G + S D++SLG +M TR+ +
Sbjct: 433 AGNELELTPVQGAWKNELAGTLAYRAPELLKGLQ-PSVRSDVYSLGITLWQMCTRQGPYE 609
Query: 205 G 205
G
Sbjct: 610 G 612
>36481
Length = 806
Score = 57.0 bits (136), Expect = 9e-09, Method: Compositional matrix adjust.
Identities = 35/130 (26%), Positives = 66/130 (50%), Gaps = 6/130 (4%)
Frame = +2
Query: 11 GEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPN------IV 64
GEGT+G V + ++ L G+ +ALK I+ + A EI++L++L + V
Sbjct: 389 GEGTFGKVVQCKDLLKGDDIALKIIK---NVDKYREAAKLEINVLEKLREKDPHAKHMCV 559
Query: 65 KLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVL 124
++LD + + F L + F+ ++ P+ ++ +QL + F H +++
Sbjct: 560 QMLDWFDYHGHVCISFHMLGLSVFDFLKDNSYGAYPIEQVRHISYQLCYAVNFLHENQLT 739
Query: 125 HRDLKPQNLL 134
H DLKP+N+L
Sbjct: 740 HTDLKPENIL 769
>22005
Length = 873
Score = 56.6 bits (135), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 62/243 (25%), Positives = 102/243 (41%), Gaps = 55/243 (22%)
Frame = +1
Query: 10 IGEGTYGVVYKAR----NKLTGEVVALK------KIRLDTETEGVPSTAIREISLLKELN 59
IG+G +G V K + L GE++ K K+ + +E + S RE SL+ + +
Sbjct: 7 IGQGAFGRVSKLKFLGLASLVGELIPEKRP*LL*KMLKEDASEDLQSDFEREASLMADFD 186
Query: 60 HPNIVKLLDVIHTENKLYLVFEFLHQ-DLKKFMDASALTGIPLPLIKS------------ 106
HPNIVKLL V + L+FEF+ + DL F+ + LP+ +S
Sbjct: 187 HPNIVKLLGVCAIGKPMCLLFEFMSKGDLNDFLRLCSPENYNLPVSRSQNLVVDLEDGLR 366
Query: 107 -----------------------------YLFQLLQ-GLAFCHSHRVLHRDLKPQNLLIN 136
Y+ Q + G+A+ +HRDL + +
Sbjct: 367 VEVEAEECEKDTQSEDRDCSGMLXTKDQLYISQQISAGMAYLAQKDYVHRDLATRTVXSR 546
Query: 137 TEGAIKLADFGLARAFGVP--VRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFA 194
T ++DFGLAR+ R + + + + E +L K +ST D+WS G +
Sbjct: 547 TT-*S*ISDFGLARSVHSVDYYRGSEQDAIPIRWMPLEAILYSK-FSTQSDVWSFGVVLW 720
Query: 195 EMV 197
E++
Sbjct: 721 EIL 729
>37602
Length = 804
Score = 43.5 bits (101), Expect(2) = 5e-08, Method: Compositional matrix adjust.
Identities = 30/91 (32%), Positives = 43/91 (47%), Gaps = 2/91 (2%)
Frame = -1
Query: 58 LNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPL--PLIKSYLFQLLQGL 115
+N V D KL++ E+ D +TG PL P I + L+GL
Sbjct: 348 VNIQTFVGYFDSYLRREKLWIAMEYCGGG--SMQDIYHVTG-PLTEPQIAFVCRETLKGL 178
Query: 116 AFCHSHRVLHRDLKPQNLLINTEGAIKLADF 146
+ H +HRD+K N+L+ EG +KLADF
Sbjct: 177 HYLHRRGKMHRDIKGANILLTEEGDVKLADF 85
Score = 30.8 bits (68), Expect(2) = 5e-08, Method: Compositional matrix adjust.
Identities = 10/22 (45%), Positives = 19/22 (86%)
Frame = -2
Query: 1 MENFQKVEKIGEGTYGVVYKAR 22
+++F+ ++++G GTYG VYKA+
Sbjct: 512 LDDFELIQRVGSGTYGDVYKAK 447
>12786
Length = 460
Score = 54.7 bits (130), Expect = 5e-08, Method: Compositional matrix adjust.
Identities = 40/127 (31%), Positives = 57/127 (44%), Gaps = 21/127 (16%)
Frame = -3
Query: 98 GIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVR 157
G+ +IK Y ++L+ + H+ V+H DLKP N ++ G +KL DFG+A
Sbjct: 422 GLDRMMIKFYWREMLRAVKALHNEGVIHSDLKPANFML-VAGNLKLIDFGIANTLQQDKT 246
Query: 158 TYTHE--VVTLWYRAPE-ILLGCK----------------YYSTAV--DIWSLGCIFAEM 196
+ + V T Y +PE I+ C Y V D+WSLGCI M
Sbjct: 245 SVLKDSRVGTPSYMSPEAIMAACDDSADDSMEEDGHRTKPKYKVGVRSDVWSLGCILYNM 66
Query: 197 VTRRALF 203
V R F
Sbjct: 65 VYGRTPF 45
>01392
Length = 1806
Score = 54.3 bits (129), Expect = 6e-08, Method: Compositional matrix adjust.
Identities = 52/189 (27%), Positives = 84/189 (44%), Gaps = 12/189 (6%)
Frame = -1
Query: 110 QLLQGLAFCHSHRVLHRDLKPQNLL---INTEGAIKLADFGLARAFGVPVR-TYTHEVVT 165
+ + L F HS + HRDLKP+N+L ++ +K+ DF LA T T E++T
Sbjct: 1767 HIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGISCDGDGTKTPELLT 1588
Query: 166 ----LWYRAPEIL---LGCKY-YSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFR 217
Y APE++ +G + Y D+WSLG I M+ F G D +
Sbjct: 1587 PVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILYIMLCGYPPFYGQCGEDCGWNRGE 1408
Query: 218 TLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISA 277
++++ S+ D FP Q+++ + + L+ +L +P KR SA
Sbjct: 1407 ACHDCQDMLF---NSIQDGHYKFPS---QEWTSI----SSSAKDLIRHLLVREPRKRYSA 1258
Query: 278 KAALAHPFF 286
L HP+
Sbjct: 1257 ADVLKHPWI 1231
>31489
Length = 329
Score = 53.1 bits (126), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 31/91 (34%), Positives = 52/91 (57%), Gaps = 8/91 (8%)
Frame = +3
Query: 52 ISLLKELNHPNIVKLLDVI------HTENKLYLVFEFLHQDLKKFMDASALTGIPL--PL 103
I +LK H NI+ + +++ H +++VF+ + DL + + + PL
Sbjct: 3 IKILKHFKHDNIISIREILKPKDSYHDFKDIHVVFDLMESDLHRIIYSDQ----PLTEEH 170
Query: 104 IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLL 134
I+ +L+Q+L+GL + HS V+HRDLKP NLL
Sbjct: 171 IRYFLYQILRGLKYIHSANVVHRDLKPSNLL 263
>18401
Length = 463
Score = 52.4 bits (124), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 39/141 (27%), Positives = 66/141 (46%), Gaps = 17/141 (12%)
Frame = -3
Query: 163 VVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGT- 221
V T YRAPE++L + S D+WS+GCI E+ T LF + L + R LG+
Sbjct: 449 VSTRHYRAPEVILELGW-SHPCDVWSVGCIMFELYTGYTLFQTHDNKEHLAMMERILGSL 273
Query: 222 ---------PDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPL-DEDGR------SLLSQ 265
+ G +P+ + S ++ R++ ++ + D + + L+ +
Sbjct: 272 PYRMAKKTKKQKYFHHGRLDVPE-RSSMARYVRENTKPLLRYVKDRENKDHQQLFDLMKK 96
Query: 266 MLHYDPNKRISAKAALAHPFF 286
+L Y+ + R S AL HPFF
Sbjct: 95 LLAYEASSRYSLLQALQHPFF 33
>26009
Length = 886
Score = 39.3 bits (90), Expect(2) = 3e-07, Method: Compositional matrix adjust.
Identities = 17/33 (51%), Positives = 25/33 (75%)
Frame = +3
Query: 105 KSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINT 137
KS + QL+ L F HS +++HRD+KP+N+LI T
Sbjct: 720 KSVMKQLVSALDFMHSKQLVHRDIKPENVLILT 818
Score = 32.3 bits (72), Expect(2) = 3e-07, Method: Compositional matrix adjust.
Identities = 30/97 (30%), Positives = 42/97 (43%), Gaps = 5/97 (5%)
Frame = +2
Query: 2 ENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELN-- 59
E++ +++G GTYG V AR + TG VALK + T +RE +L+
Sbjct: 416 EHYDVCKELGRGTYGKVVLARCRHTGTQVALKLL-------PKSCTKLREFQREFQLSYF 574
Query: 60 ---HPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDA 93
H NI+ +V Y VF H L DA
Sbjct: 575 LSPHANIIDTYNVAFQTRSSY-VFAQEHAVLGDLFDA 682
>11404
Length = 563
Score = 52.0 bits (123), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 41/134 (30%), Positives = 67/134 (50%), Gaps = 8/134 (5%)
Frame = +1
Query: 10 IGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPN------I 63
IG+G++G V KA + E VA+K I+ + + A E+ LL+ +N + I
Sbjct: 163 IGKGSFGQVVKAYDHTDNEQVAIKIIK---NKKPFLNQAQIEVKLLEMMNRHDTDNKYYI 333
Query: 64 VKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHS--H 121
V+L + L LVFE L +L + + G+ L L + + QL L F +
Sbjct: 334 VRLKRHFMFRSHLCLVFELLSYNLYDLLRNTNFRGVSLNLTRKFAQQLCTALLFLATPEM 513
Query: 122 RVLHRDLKPQNLLI 135
++H DLKP+N+L+
Sbjct: 514 SIIHCDLKPENILL 555
>21079
Length = 878
Score = 50.8 bits (120), Expect = 6e-07, Method: Compositional matrix adjust.
Identities = 41/138 (29%), Positives = 66/138 (47%), Gaps = 5/138 (3%)
Frame = +1
Query: 60 HPNIVKLLDVIHTENKLYLVFEFLHQDL---KKFMDASALTGIPLPLIKSYLFQLLQGLA 116
HP ++ L D + LV EF+ + D LT ++ Q+ G+
Sbjct: 1 HPKLLMLWDAFEAPRTMVLVMEFVGAGELFERVIRDDFVLTERDC---VHFVRQICSGVG 171
Query: 117 FCHSHRVLHRDLKPQNLLINTEGA--IKLADFGLARAFGVPVRTYTHEVVTLWYRAPEIL 174
+ H+ +LH DLKP+N+L ++ + IK+ DFGLAR F P + T + APE+
Sbjct: 172 YMHTQSILHLDLKPENVLCVSDNSNQIKIIDFGLAR-FYKPGDSLQVLFGTPEFIAPEV- 345
Query: 175 LGCKYYSTAVDIWSLGCI 192
+ + D+WS+G I
Sbjct: 346 VNYDEINFTTDMWSIGVI 399
>07291
Length = 833
Score = 50.8 bits (120), Expect = 7e-07, Method: Compositional matrix adjust.
Identities = 25/94 (26%), Positives = 53/94 (56%), Gaps = 4/94 (4%)
Frame = +1
Query: 110 QLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVT---- 165
Q+ G+A+ +V+HR+L +N ++ +G ++L+D+G+ + P YT +
Sbjct: 73 QIADGMAYLQEVKVVHRNLAARNCIVTEDGRLQLSDYGVTGSL-FPQSYYTADDSPARDL 249
Query: 166 LWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTR 199
+ + APE + ++S+ D+W+ G + E++TR
Sbjct: 250 VKWMAPETIDNF-HFSSKSDVWAFGVVLWELLTR 348
>02638
Length = 1490
Score = 50.1 bits (118), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 40/134 (29%), Positives = 59/134 (44%), Gaps = 2/134 (1%)
Frame = +1
Query: 165 TLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDE 224
T+ + APE+L G + Y A D+WS+GC+ EM T R + + L IF+ + D
Sbjct: 25 TIAFMAPEVLRG-ESYGRACDVWSVGCVMIEMCTCRPPWNSHDISNHLALIFKIASSVD- 198
Query: 225 VVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHP 284
P P+ + PP+ R L+ + L D + R SAK L HP
Sbjct: 199 ------------PPPIPE-------NMSPPV----RDLMLRCLEQDSDFRPSAKDLLMHP 309
Query: 285 FFQDVTK--PVPHL 296
F ++ P P L
Sbjct: 310 LFTKYSQG*PXPSL 351
>05084
Length = 1324
Score = 49.7 bits (117), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 34/97 (35%), Positives = 48/97 (49%), Gaps = 3/97 (3%)
Frame = +2
Query: 203 FPGDSEIDQLFRIFRTLGTPDEVVWPGVTSM-PDYKP-SFPKWARQDFSKVVPP-LDEDG 259
PGDS +DQL I + LGTP + M P+Y FP+ ++KV P +
Sbjct: 2 LPGDSGVDQLVEIIKVLGTPTRE---QIREMNPNYSEFKFPQIKAHPWTKVFRPRTPPEA 172
Query: 260 RSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHL 296
L+S++L Y P+ RI A AH FF ++ P L
Sbjct: 173 IQLVSRLLEYTPSARIQPMEACAHAFFDELRDPASRL 283
>29360
Length = 363
Score = 49.3 bits (116), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 37/124 (29%), Positives = 61/124 (49%), Gaps = 8/124 (6%)
Frame = +3
Query: 20 KARNKLTGEVVALKKIRLDTETEGVPSTAIR---EISLLKELNHP-----NIVKLLDVIH 71
K K T E+VA+K ++ PS A + E+S+L+ L+ N V+ +
Sbjct: 6 KCWKKGTSEIVAIKILK------NHPSYARQGQIEVSILQRLSQESADDYNFVRAFECFQ 167
Query: 72 TENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQ 131
+N LVFE L Q+L F+ + +PL I+ Q+L L ++H DLKP+
Sbjct: 168 HKNHTCLVFEMLEQNLYDFLKQNKFQPLPLKYIRPITQQVLTALRKLKQLGLIHADLKPE 347
Query: 132 NLLI 135
N+++
Sbjct: 348 NIML 359
>26909
Length = 394
Score = 48.5 bits (114), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 35/121 (28%), Positives = 55/121 (45%), Gaps = 18/121 (14%)
Frame = +2
Query: 192 IFAEMVTRRALFPGDSEI---------DQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPK 242
IFAE++T +F E DQL RIF +G P E W + MP+++
Sbjct: 2 IFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFPQEKDWEDIRRMPEHQQLTKD 181
Query: 243 WARQDF---------SKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPV 293
+ R + K D LL ++L DP KRI+++ A+ P+F + +P+
Sbjct: 182 FKRSSYVNCNLMKYMEKHKVKADSKAFHLLQKLLTMDPVKRITSEQAMKDPYF--LEEPL 355
Query: 294 P 294
P
Sbjct: 356 P 358
>21800
Length = 855
Score = 46.6 bits (109), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 34/102 (33%), Positives = 55/102 (53%), Gaps = 13/102 (12%)
Frame = +2
Query: 47 TAIREISLLKELNHPN--------IVKLLDVIHTE----NKLYLVFEFLHQDLKKFMDAS 94
TA+ EI LLK + + + V+LLD + +VFE L +L K + S
Sbjct: 431 TALDEIKLLKCVRNSDETDPAREKSVQLLDDFKISGVNGTHVCMVFEVLGYNLLKLIIRS 610
Query: 95 ALTGIPLPLIKSYLFQLLQGLAFCHSH-RVLHRDLKPQNLLI 135
GIP+ +K + Q+L+GL + H+ ++H D+KP+N+LI
Sbjct: 611 NYQGIPVHNVKLIIRQVLEGLNYLHAKCNIIHTDIKPENILI 736
>20640
Length = 1492
Score = 45.1 bits (105), Expect = 4e-05, Method: Compositional matrix adjust.
Identities = 25/75 (33%), Positives = 42/75 (56%), Gaps = 2/75 (2%)
Frame = +1
Query: 124 LHRDLKPQNLLINTEGAIKLADFGLARAFGVP--VRTYTHEVVTLWYRAPEILLGCKYYS 181
+HRDL +N L+ + +K++DFGLAR+ R H+ + + + E +L K +S
Sbjct: 10 VHRDLATRNCLVGHDLVVKISDFGLARSVHSVDYYRGSEHDAIPIRWMPLEAILYNK-FS 186
Query: 182 TAVDIWSLGCIFAEM 196
T D+WS G + E+
Sbjct: 187 TQSDVWSFGVVLWEI 231
>06358
Length = 1517
Score = 44.7 bits (104), Expect = 5e-05, Method: Compositional matrix adjust.
Identities = 71/319 (22%), Positives = 126/319 (39%), Gaps = 33/319 (10%)
Frame = +3
Query: 4 FQKVEKIGEGTYGVVYKARNKLTGE---VVALKKIRLDT----ETEGVPSTAIREISLLK 56
+ +V G G V+ A K T E V +K +D + E + + L
Sbjct: 12 YNQVASAGPGLLWKVFAASKKSTKEEASVFVFEKKSVDRYSRRDREAIVEVLRVGVQQLT 191
Query: 57 ELNHPNIVKLLDVIH-TENKLYLVFEFLHQDLKKFM-DASALTGIPLPL---------IK 105
+L HP I+ +++ + + L E + L + D S++ +P L IK
Sbjct: 192 KLRHPKILAVINPLEESRETLAFATEPVFASLANVLGDLSSIXTVPKELQDYQLYDVEIK 371
Query: 106 SYLFQLLQGLAFCHSH-RVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVV 164
L Q+ + L F H+ +++HR++ P+ +++ G+ KLA + P T
Sbjct: 372 HGLLQVTEALGFLHNDAKMMHRNVCPEAIMLTKLGSWKLAGYEFCVRSSDPQSTDPSYPF 551
Query: 165 TLW-------------YRAPEILLGCKYYSTAVDIWSLG-CIFAEMVTRRALFPGDSEID 210
W + APE +L + T D++SLG +++ + LF + E+
Sbjct: 552 YEWRSDIAPVTQPHLDFMAPEYVLTMQ-CGTGSDMFSLGLLVYSVFAKGKPLFECNGELS 728
Query: 211 QLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYD 270
F++ +E+ + R VVP ED R + +L+ +
Sbjct: 729 A----FKS--NAEEL----------------RHMRVSLLGVVP---EDLRDHVKLLLNIE 833
Query: 271 PNKRISAKAALAHPFFQDV 289
P R A PFF+DV
Sbjct: 834 PAVRPDAAQLSKVPFFEDV 890
>28157
Length = 400
Score = 44.3 bits (103), Expect = 5e-05, Method: Compositional matrix adjust.
Identities = 40/130 (30%), Positives = 64/130 (49%), Gaps = 10/130 (7%)
Frame = +3
Query: 30 VALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQ-DLK 88
VA+K+I E+E + ++E+ L ++HPNIV L ++ + LV E+ L
Sbjct: 9 VAVKRI----ESEQEKKSFMQELKQLSRVSHPNIVCLYGAC-RDHPVCLVMEYAEGGSLY 173
Query: 89 KFMDASALTGIPLPLIKS-----YLFQLLQGLAFCHSHR---VLHRDLKPQNLLINTEGA 140
+ S P P + +L Q G+ + H + ++HRDLKP NLL+ G
Sbjct: 174 NVLHGSG----PQPQYTAAHAMNWLLQCALGVEYLHGMKPKALIHRDLKPPNLLLIQCGT 341
Query: 141 -IKLADFGLA 149
+K+ DFG A
Sbjct: 342 KLKICDFGTA 371
>20152
Length = 445
Score = 44.3 bits (103), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 34/119 (28%), Positives = 47/119 (39%), Gaps = 1/119 (0%)
Frame = +1
Query: 171 PEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGV 230
PEILLG Y + AVD+WSLG I +V A F ++ + L I
Sbjct: 1 PEILLGDSYDAPAVDVWSLGVILYMLVVGEAPFQEANDSETLTMIM-------------- 138
Query: 231 TSMPDYKPSFPKWARQDFSKVVPP-LDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQD 288
D +PP + + L+ +ML +P R S LAHP+ D
Sbjct: 139 ----------------DCRYQIPPHISHKCQDLIEKMLQREPVDRASLPHILAHPWLND 267
>16708
Length = 1397
Score = 43.5 bits (101), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 45/174 (25%), Positives = 67/174 (38%), Gaps = 7/174 (4%)
Frame = -1
Query: 110 QLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGV-PVRTYTHEVV---- 164
Q + L H V+H D+K N+L++ G KL D+G+A+ + V P T TH
Sbjct: 1070 QXVCALEHIHELGVVHMDVKADNVLVDAHGNCKLTDYGIAQLYKVYPAPTETHSSGCTNK 891
Query: 165 -TLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPD 223
T + R P + + +S GD FR+ + L T
Sbjct: 890 RTFYTRPPATMTPSERFSEE---------------------GDGIGTDYFRLGQMLWTLT 774
Query: 224 EVVWPGV-TSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRIS 276
V V S P P P W R S++ D + ++ H DPN R+
Sbjct: 773 GAVLLHVWVSRP---PKLPDWCRTPESELSGMSD-----FIEKLCHGDPNMRLG 636
>13078
Length = 773
Score = 43.1 bits (100), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 35/127 (27%), Positives = 57/127 (44%), Gaps = 17/127 (13%)
Frame = -1
Query: 180 YSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGT----------PDEVVWPG 229
+S D+WS+GCI E+ T LF + L + R LG+ + + G
Sbjct: 746 WSQPCDVWSIGCIMFELYTGYTLFQTHDNKEHLAMMERILGSLPYRMAKKTKKQKYFYHG 567
Query: 230 VTSMPDYKPSFPKWARQDFSK----VVPPLDEDGRS---LLSQMLHYDPNKRISAKAALA 282
D K S ++ R + V P +ED + L+ +ML Y+ + R S + A+
Sbjct: 566 RLDW-DEKSSAGRYVRDNVKPLRRYVKDPDNEDHQQLFDLMDKMLSYEVSTRYSLRQAMR 390
Query: 283 HPFFQDV 289
HPFF+ +
Sbjct: 389 HPFFRKL 369
>17300
Length = 480
Score = 43.1 bits (100), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 24/92 (26%), Positives = 46/92 (50%), Gaps = 4/92 (4%)
Frame = +1
Query: 111 LLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEV----VTL 166
+ G+ +HRDL +N+L+N K+ADFGL+R + + +
Sbjct: 1 ISSGMGXLADMGYVHRDLAARNILVNEILVCKVADFGLSREIESDTTEGAYTTKGGKIPV 180
Query: 167 WYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT 198
+ APE + + +++A D+WS G + E+++
Sbjct: 181 RWTAPE-AIAYRKFTSASDVWSFGVVMWEVMS 273
>00638
Length = 1595
Score = 42.0 bits (97), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 16/33 (48%), Positives = 25/33 (75%)
Frame = +2
Query: 104 IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLIN 136
I+ YL++L++ L FCHS ++HRD+KP L+N
Sbjct: 422 IRFYLYELMKALDFCHSMGIMHRDVKPSPPLVN 520
>31789
Length = 676
Score = 41.6 bits (96), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 33/113 (29%), Positives = 53/113 (46%), Gaps = 6/113 (5%)
Frame = +2
Query: 9 KIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLD 68
+IG G++ VYK + G VA +++ + E +LKEL HPNIV+ D
Sbjct: 341 EIGRGSFKTVYKGLDTELGVAVAWCELQDKKWNKTERQRFKEEAEMLKELQHPNIVRFFD 520
Query: 69 VIHTENK-----LYLVFEFLHQD-LKKFMDASALTGIPLPLIKSYLFQLLQGL 115
N + LV E + LK ++ I L ++K++ Q+L+GL
Sbjct: 521 YWEEHNHRNRKVIILVTELMTSGTLKTYL--KRFKKINLKVLKNWCRQILKGL 673
>25019
Length = 730
Score = 41.6 bits (96), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 27/73 (36%), Positives = 38/73 (52%)
Frame = +3
Query: 131 QNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLG 190
+N+L++ +G +KL DFGL + R T+ Y APEIL + AVD WSLG
Sbjct: 261 ENVLLDKDGHVKLTDFGLCKEAITGTRVTHTFCGTIEYMAPEILTRTGH-GKAVDWWSLG 437
Query: 191 CIFAEMVTRRALF 203
+ V R + F
Sbjct: 438 SSYV*YVDRISTF 476
>12672
Length = 773
Score = 40.0 bits (92), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 25/92 (27%), Positives = 47/92 (51%), Gaps = 6/92 (6%)
Frame = +3
Query: 113 QGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLA----RAFGVPVRTYTHEVVTLWY 168
G+ + + + +HRD+K N+L+++E K+ DF G V+ + + T Y
Sbjct: 24 SGIQYLNDNGHVHRDIKTANILLDSEYTAKVGDFATVVSAPSGEGKTVQNASVVIGTAAY 203
Query: 169 RAPEILLGCKYY--STAVDIWSLGCIFAEMVT 198
APE + ++ ST +D +S G + E++T
Sbjct: 204 LAPEAI----HFDVSTKLDSYSFGVVLLEVIT 287
>15549
Length = 470
Score = 39.3 bits (90), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 14/40 (35%), Positives = 30/40 (75%)
Frame = -1
Query: 2 ENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTET 41
+ F+ +E++G+G YG+V++A+NK+ + A+K+I L ++
Sbjct: 218 DEFECIEQMGKGGYGIVFRAKNKVDEQEYAVKRIALPSDA 99
>00394
Length = 548
Score = 37.7 bits (86), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 21/66 (31%), Positives = 31/66 (46%)
Frame = -2
Query: 9 KIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLD 68
+IG G++ VYK + G VA +++ + E +LKEL HPNIV+ D
Sbjct: 277 EIGRGSFKTVYKGLDTELGVAVAWCELQDKKWNKAERQRFKEEAEMLKELQHPNIVRFFD 98
Query: 69 VIHTEN 74
N
Sbjct: 97 YWEEHN 80
>38560
Length = 479
Score = 37.7 bits (86), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 35/127 (27%), Positives = 49/127 (38%), Gaps = 1/127 (0%)
Frame = -3
Query: 168 YRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVW 227
Y APE++ G +Y + DIWS+G + ++ P D E + DEV
Sbjct: 387 YAAPELISGLEYLGSEADIWSMGVLLYALLC--GYLPFDDEKXSHL*Q-KNQKRKDEV-- 223
Query: 228 PGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFF- 286
P+W L ED LL ML DP+ RI+ + L H +
Sbjct: 222 -------------PEW-----------LSEDTTKLLEGMLQTDPSHRITIRRLLDHHWLN 115
Query: 287 QDVTKPV 293
Q PV
Sbjct: 114 QGFNVPV 94
>07836
Length = 1478
Score = 37.4 bits (85), Expect = 0.007, Method: Compositional matrix adjust.
Identities = 50/206 (24%), Positives = 90/206 (43%), Gaps = 24/206 (11%)
Frame = -1
Query: 27 GEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLL--DVIHTEN--KLYLVFEF 82
GE VA+K E T + + LL+ H NI+ + D+ T + +L+L+ ++
Sbjct: 1478 GENVAVKIFFTTEEASWFRETELYQTVLLR---HENILGFIAADIKGTGSWTQLFLITDY 1308
Query: 83 LHQD-------LKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI 135
H++ L + +D+S + + I ++ + HRD+K +N+L+
Sbjct: 1307 -HENGSLHDYLLSRVLDSSEMLALAHSAICGLAHLHIEIFGTRGKPAIAHRDIKSKNILV 1131
Query: 136 NTEGAIKLADFGLARAFGVPVRTYTHEV--------VTLWYRAPEI---LLGCKYYST-- 182
G +AD GLA V + ++EV T Y APE+ LL K +
Sbjct: 1130 KKNGTCCIADLGLA----VRYISESNEVDVAPNPRQGTKRYMAPEVLEMLLNVKNFDAFK 963
Query: 183 AVDIWSLGCIFAEMVTRRALFPGDSE 208
D+++ G + E + R + G +E
Sbjct: 962 QADMYAFGLVMWE-IARCCVIGGVAE 888
>18481
Length = 437
Score = 34.3 bits (77), Expect = 0.071, Method: Compositional matrix adjust.
Identities = 18/46 (39%), Positives = 25/46 (54%), Gaps = 3/46 (6%)
Frame = -1
Query: 110 QLLQGLAFCHSHRVLHRDLKPQNLLINTE---GAIKLADFGLARAF 152
QLL L F H +HRDLKP N L+ + + DFGL++ +
Sbjct: 173 QLLSRLEFIHQKCFIHRDLKPDNFLMGLGRHCHRLYIIDFGLSKRY 36
>35032
Length = 465
Score = 33.9 bits (76), Expect = 0.091, Method: Compositional matrix adjust.
Identities = 13/25 (52%), Positives = 20/25 (80%)
Frame = +3
Query: 262 LLSQMLHYDPNKRISAKAALAHPFF 286
L+ ++L+YDP+KR++ ALAHPF
Sbjct: 150 LVKRLLNYDPSKRLTPXXALAHPFL 224
>00486
Length = 797
Score = 33.1 bits (74), Expect = 0.16, Method: Compositional matrix adjust.
Identities = 27/113 (23%), Positives = 46/113 (40%)
Frame = -2
Query: 165 TLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDE 224
T+ Y APEIL + AVD WSLG + +M+T F ++ + +I +
Sbjct: 769 TIEYMAPEILTRTGH-GKAVDWWSLGALMYDMLTGSPPFTAENRKKTIDKILK------- 614
Query: 225 VVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISA 277
G ++P Y L + R L+ ++L +P +R+
Sbjct: 613 ----GKLNLPPY------------------LTNEARGLIKKLLRKNPAERLGG 521
>17806
Length = 433
Score = 32.7 bits (73), Expect = 0.19, Method: Compositional matrix adjust.
Identities = 31/124 (25%), Positives = 56/124 (45%), Gaps = 9/124 (7%)
Frame = +1
Query: 7 VEKIGEGTYGVVYKARNKLTGEVVALKKIRL----DTETEGVPSTAIREISLLKELNHPN 62
++++G G +G V ++ + V+ K+ + D T+ E++ +EL+HPN
Sbjct: 64 LKELGTGWFGKVIESDAERITTGVSRSKVVVKMLKDDATKDEQLLFFEEVAPFRELDHPN 243
Query: 63 IVKLLDVIHTENKLYLVFEF-----LHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAF 117
IV+LL N + ++ E L Q L+ A+ L+K + + GLA
Sbjct: 244 IVRLLGQCTEMNPMLMLMECAALGNLKQYLRNHRHQQAMLIQKNRLLK-FAMDISSGLAC 420
Query: 118 CHSH 121
H H
Sbjct: 421 LHGH 432
>17644
Length = 463
Score = 30.8 bits (68), Expect = 0.75, Method: Compositional matrix adjust.
Identities = 11/24 (45%), Positives = 19/24 (79%)
Frame = +3
Query: 262 LLSQMLHYDPNKRISAKAALAHPF 285
L+ ++L YDP++R++ AL+HPF
Sbjct: 90 LVQRLLTYDPSQRLTPDLALSHPF 161
>20773
Length = 391
Score = 30.4 bits (67), Expect = 0.94, Method: Compositional matrix adjust.
Identities = 11/25 (44%), Positives = 20/25 (80%)
Frame = -1
Query: 261 SLLSQMLHYDPNKRISAKAALAHPF 285
+L+ ++L YDP++R++ AL+HPF
Sbjct: 304 NLVQRLLTYDPSQRLTPDLALSHPF 230
>15931
Length = 447
Score = 29.3 bits (64), Expect = 1.9, Method: Compositional matrix adjust.
Identities = 15/40 (37%), Positives = 24/40 (60%), Gaps = 3/40 (7%)
Frame = +1
Query: 251 VVPPLDEDGRSL---LSQMLHYDPNKRISAKAALAHPFFQ 287
V P +ED + L + +ML Y+ + R S + A+ HPFF+
Sbjct: 40 VKDPDNEDHQQLFDLMDKMLSYEVSTRYSLRQAMRHPFFR 159
>07833
Length = 1504
Score = 28.9 bits (63), Expect = 2.3, Method: Compositional matrix adjust.
Identities = 39/178 (21%), Positives = 77/178 (43%), Gaps = 8/178 (4%)
Frame = -3
Query: 41 TEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIP 100
T+ + + E L+ NHPN++ +L + L L+ +F+ + +GI
Sbjct: 1499 TKRITRDFMEEFPRLRIFNHPNVLPVLACCNQPPNLVLISQFMPFG-SLYNTLHGESGIV 1323
Query: 101 LPLIKSYLFQL--LQGLAFCHSHR--VLHRDLKPQNLLINTE--GAIKLADFGLARAFGV 154
+ +S F + +G+ F HS + + L ++++I+ + I +AD+ +F
Sbjct: 1322 VDQNQSLRFAMDIARGMEFLHSMEPTIPNFLLTSKHVMIDEDLTARINMADYCF--SFHE 1149
Query: 155 PVRTYTHEVVTLWYRAPEILLG--CKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEID 210
+ Y+ + APE L + A D+WS + E+ TR F S ++
Sbjct: 1148 KGKVYSPA-----WMAPEALQRRPDDINTRAADMWSFAILMWELETREVPFAELSSME 990
>20513
Length = 405
Score = 28.5 bits (62), Expect = 3.5, Method: Compositional matrix adjust.
Identities = 12/34 (35%), Positives = 19/34 (55%)
Frame = -1
Query: 261 SLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP 294
L+ ML +DP +R +A +L HP+ + P P
Sbjct: 282 DFLAPMLEFDPEQRATAAQSLQHPWLKLDA*PEP 181
>16350
Length = 1108
Score = 28.5 bits (62), Expect = 3.5, Method: Compositional matrix adjust.
Identities = 10/27 (37%), Positives = 17/27 (62%)
Frame = +3
Query: 261 SLLSQMLHYDPNKRISAKAALAHPFFQ 287
L+ ML +DP +R +A +L HP+ +
Sbjct: 762 DFLAPMLEFDPEQRATAAQSLQHPWLK 842
>08279
Length = 1022
Score = 28.5 bits (62), Expect = 3.8, Method: Compositional matrix adjust.
Identities = 15/54 (27%), Positives = 26/54 (48%)
Frame = +1
Query: 164 VTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFR 217
V ++R ++ C++ S VD+WS GC + PG EI ++ + R
Sbjct: 625 VVTFHRPQHLVDVCRHSSHYVDLWSHGC-------SPCVVPGRGEISKVCPLVR 765
>26565
Length = 497
Score = 27.7 bits (60), Expect = 5.2, Method: Compositional matrix adjust.
Identities = 16/32 (50%), Positives = 19/32 (59%)
Frame = +3
Query: 58 LNHPNIVKLLDVIHTENKLYLVFEFLHQDLKK 89
L+HPN V L IHT +K Y + LH LKK
Sbjct: 339 LHHPNNVSFLFYIHTISKYYFMH*HLHFKLKK 434
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000380643 | hsapiens_gene_ensembl | Paxillin.
[Source:Uniprot/SWISSPROT;Acc:P49023]
(403 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
11928 332 2e-91
09680 129 2e-30
07437 127 7e-30
14307 87 2e-17
05726 74 9e-14
34420 44 1e-04
26762 43 2e-04
05103 38 0.008
30169 35 0.047
15283 29 3.1
17933 29 3.6
32935 28 9.6
>11928
Length = 1623
Score = 332 bits (850), Expect = 2e-91, Method: Compositional matrix adjust.
Identities = 152/221 (68%), Positives = 176/221 (79%)
Frame = -2
Query: 162 VATVAKGVCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDY 221
V T KGVC AC KPI GQV+ A+G+TWH EHFVC HC++ +G+ NF+ERD YCE DY
Sbjct: 1622 VNTKKKGVCAACNKPIVGQVIAALGRTWHVEHFVCAHCEQPLGTSNFYERDSVAYCEVDY 1443
Query: 222 HNLFSPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYF 281
HNLF+PRC YCNGPI+DK +TAL++ WHPEHFFCAQCG FG E FHEK+GKAYCR DYF
Sbjct: 1442 HNLFAPRCAYCNGPIVDKCITALEKMWHPEHFFCAQCGRQFGDEDFHEKNGKAYCRDDYF 1263
Query: 282 DMFAPKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHE 341
MFAPKCGGC I+ENYISALN WHP+CF C EC PF GSF++HDG PYCE HYH
Sbjct: 1262 QMFAPKCGGCGMPIMENYISALNRQWHPQCFCCWECQAPFGTGSFYDHDGLPYCETHYHA 1083
Query: 342 RRGSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNK 382
++GSLC+ CQKPITGRCITAM KKFHPEH FCL+ L++
Sbjct: 1082 KKGSLCASCQKPITGRCITAMFKKFHPEH----FCLRLLHQ 972
Score = 139 bits (350), Expect = 2e-33, Method: Compositional matrix adjust.
Identities = 67/168 (39%), Positives = 94/168 (55%)
Frame = -2
Query: 229 CYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKC 288
C CN PI+ +V+ AL RTWH EHF CA C G F+E+D AYC DY ++FAP+C
Sbjct: 1598 CAACNKPIVGQVIAALGRTWHVEHFVCAHCEQPLGTSNFYERDSVAYCEVDYHNLFAPRC 1419
Query: 289 GGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCS 348
C I++ I+AL +WHPE F C +C F + F E +G+ YC Y + C
Sbjct: 1418 AYCNGPIVDKCITALEKMWHPEHFFCAQCGRQFGDEDFHEKNGKAYCRDDYFQMFAPKCG 1239
Query: 349 GCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQN 396
GC PI I+A+ +++HP+ F C C G+F + + PYC+
Sbjct: 1238 GCGMPIMENYISALNRQWHPQCFCCWECQAPFGTGSFYDHDGLPYCET 1095
Score = 102 bits (253), Expect = 4e-22, Method: Compositional matrix adjust.
Identities = 48/115 (41%), Positives = 64/115 (55%)
Frame = -2
Query: 288 CGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLC 347
C C + I+ I+AL WH E FVC C P +F+E D YCEV YH C
Sbjct: 1598 CAACNKPIVGQVIAALGRTWHVEHFVCAHCEQPLGTSNFYERDSVAYCEVDYHNLFAPRC 1419
Query: 348 SGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 402
+ C PI +CITA+ K +HPEHF CA C +Q F E+N K YC++ + ++F
Sbjct: 1418 AYCNGPIVDKCITALEKMWHPEHFFCAQCGRQFGDEDFHEKNGKAYCRDDYFQMF 1254
Score = 68.6 bits (166), Expect = 5e-12, Method: Compositional matrix adjust.
Identities = 29/40 (72%), Positives = 33/40 (82%)
Frame = -3
Query: 363 AKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 402
++ F FVCAFC+KQLNKGTFKEQNDKPYC CF+KLF
Sbjct: 1018 SRSFTRSIFVCAFCIKQLNKGTFKEQNDKPYCHPCFVKLF 899
Score = 53.9 bits (128), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 23/61 (37%), Positives = 36/61 (59%)
Frame = -2
Query: 342 RRGSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKL 401
++ +C+ C KPI G+ I A+ + +H EHFVCA C + L F E++ YC+ + L
Sbjct: 1613 KKKGVCAACNKPIVGQVIAALGRTWHVEHFVCAHCEQPLGTSNFYERDSVAYCEVDYHNL 1434
Query: 402 F 402
F
Sbjct: 1433 F 1431
Score = 28.9 bits (63), Expect = 3.5, Method: Compositional matrix adjust.
Identities = 11/40 (27%), Positives = 21/40 (52%)
Frame = -3
Query: 186 GKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLF 225
+++ FVC C +++ F E++ +PYC + LF
Sbjct: 1018 SRSFTRSIFVCAFCIKQLNKGTFKEQNDKPYCHPCFVKLF 899
>09680
Length = 878
Score = 129 bits (325), Expect = 2e-30, Method: Compositional matrix adjust.
Identities = 67/186 (36%), Positives = 96/186 (51%), Gaps = 3/186 (1%)
Frame = -2
Query: 153 LQSDLNKLGVATVAKGV--CGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFE 210
++S N+ +A +AK C C + I +VV A+GK +HPEHF+C C ++I F
Sbjct: 769 MESKTNE-EIALIAKQQYQCHKCNEAITSRVVFALGKNYHPEHFLCRDCDKQIKDDIFNI 593
Query: 211 RDGQPYCEKDYHNLFSPRCYYCNGPILDKVVTALDRTWHPEHFFC-AQCGAFFGPEGFHE 269
+ G+P C Y ++ C C PI ++A+ WH F C C F E
Sbjct: 592 QQGEPVCNACYLERYTSTCAGCKEPIHGTTISAMGNNWHEHCFVCDGACKQPLKDSSFFE 413
Query: 270 KDGKAYCRKDYFDMFAPKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEH 329
++GKAYCR+DY D+FA +C C + I EN I A+N WH +CF C C P +F
Sbjct: 412 REGKAYCRQDYEDLFAVRCAKCEKPITENAIVAMNAKWHSDCFCCNRCDNPIKTKTFTIE 233
Query: 330 DGQPYC 335
+P C
Sbjct: 232 GDKPIC 215
Score = 121 bits (303), Expect = 6e-28, Method: Compositional matrix adjust.
Identities = 63/171 (36%), Positives = 85/171 (49%), Gaps = 1/171 (0%)
Frame = -2
Query: 228 RCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPK 287
+C+ CN I +VV AL + +HPEHF C C + F+ + G+ C Y + +
Sbjct: 718 QCHKCNEAITSRVVFALGKNYHPEHFLCRDCDKQIKDDIFNIQQGEPVCNACYLERYTST 539
Query: 288 CGGCARAILENYISALNTLWHPECFVCR-ECFTPFVNGSFFEHDGQPYCEVHYHERRGSL 346
C GC I ISA+ WH CFVC C P + SFFE +G+ YC Y +
Sbjct: 538 CAGCKEPIHGTTISAMGNNWHEHCFVCDGACKQPLKDSSFFEREGKAYCRQDYEDLFAVR 359
Query: 347 CSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNC 397
C+ C+KPIT I AM K+H + F C C + TF + DKP C C
Sbjct: 358 CAKCEKPITENAIVAMNAKWHSDCFCCNRCDNPIKTKTFTIEGDKPICPAC 206
Score = 76.3 bits (186), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 44/117 (37%), Positives = 60/117 (51%), Gaps = 1/117 (0%)
Frame = -2
Query: 287 KCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSL 346
+C C AI + AL +HPE F+CR+C + F G+P C Y ER S
Sbjct: 718 QCHKCNEAITSRVVFALGKNYHPEHFLCRDCDKQIKDDIFNIQQGEPVCNACYLERYTST 539
Query: 347 CSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQ-LNKGTFKEQNDKPYCQNCFLKLF 402
C+GC++PI G I+AM +H FVC KQ L +F E+ K YC+ + LF
Sbjct: 538 CAGCKEPIHGTTISAMGNNWHEHCFVCDGACKQPLKDSSFFEREGKAYCRQDYEDLF 368
>07437
Length = 951
Score = 127 bits (320), Expect = 7e-30, Method: Compositional matrix adjust.
Identities = 74/227 (32%), Positives = 110/227 (48%), Gaps = 7/227 (3%)
Frame = +3
Query: 182 VTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYC-----EKDYHNLFSPRCYYCNGPI 236
+ AM WHP+ F+C C + F + G+ C ++ C+ C+ I
Sbjct: 3 IKAMNSAWHPQCFLCQLCGTCMADSGFVKNAGRALCRECNAKEKARGTGKYVCHKCHDVI 182
Query: 237 -LDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAI 295
++ + +HP HF C CG E EKD + YC + + M P CG C R I
Sbjct: 183 EMNGHIKFRGEAYHPYHFNCHSCGVELNTEA-REKDSELYCLRCHDKMGIPICGACRRPI 359
Query: 296 LENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPIT 355
E + AL WH E FVC +C PF+ +E G YCE+HYH+ G++C C I
Sbjct: 360 EERVVHALGKAWHVEHFVCAKCEKPFLGTRHYEKKGLAYCEIHYHQLFGNICFVCNNIIN 539
Query: 356 GRCITAMAKKFHPEHFVCAFCLKQLNKGT-FKEQNDKPYCQNCFLKL 401
G +A K + HF C+ C +++++ T F E + KP C+NC+ K
Sbjct: 540 GDVFSAFNKAWCVHHFACSICDRKMSQKTKFFEFDQKPVCKNCYDKF 680
Score = 91.7 bits (226), Expect = 5e-19, Method: Compositional matrix adjust.
Identities = 62/184 (33%), Positives = 83/184 (45%), Gaps = 2/184 (1%)
Frame = +3
Query: 165 VAKGVCGACKKPI-AGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHN 223
K VC C I + G+ +HP HF C C E+ + E+D + YC + +
Sbjct: 144 TGKYVCHKCHDVIEMNGHIKFRGEAYHPYHFNCHSCGVELNTEAR-EKDSELYCLRCHDK 320
Query: 224 LFSPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDM 283
+ P C C PI ++VV AL + WH EHF CA+C F +EK G AYC Y +
Sbjct: 321 MGIPICGACRRPIEERVVHALGKAWHVEHFVCAKCEKPFLGTRHYEKKGLAYCEIHYHQL 500
Query: 284 FAPKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGS-FFEHDGQPYCEVHYHER 342
F C C I + SA N W F C C + FFE D +P C+ Y +
Sbjct: 501 FGNICFVCNNIINGDVFSAFNKAWCVHHFACSICDRKMSQKTKFFEFDQKPVCKNCYDKF 680
Query: 343 RGSL 346
G L
Sbjct: 681 PGEL 692
Score = 91.7 bits (226), Expect = 5e-19, Method: Compositional matrix adjust.
Identities = 53/139 (38%), Positives = 74/139 (53%), Gaps = 1/139 (0%)
Frame = +3
Query: 147 DSMLGSLQSDLNKLGVATVAKGVCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSR 206
DS L L+ +K+G+ +CGAC++PI +VV A+GK WH EHFVC C++
Sbjct: 285 DSELYCLRCH-DKMGIP-----ICGACRRPIEERVVHALGKAWHVEHFVCAKCEKPFLGT 446
Query: 207 NFFERDGQPYCEKDYHNLFSPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEG 266
+E+ G YCE YH LF C+ CN I V +A ++ W HF C+ C +
Sbjct: 447 RHYEKKGLAYCEIHYHQLFGNICFVCNNIINGDVFSAFNKAWCVHHFACSICDRKMSQKT 626
Query: 267 -FHEKDGKAYCRKDYFDMF 284
F E D K C K+ +D F
Sbjct: 627 KFFEFDQKPVC-KNCYDKF 680
Score = 72.0 bits (175), Expect = 4e-13, Method: Compositional matrix adjust.
Identities = 52/169 (30%), Positives = 77/169 (45%), Gaps = 7/169 (4%)
Frame = +3
Query: 241 VTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAP-----KCGGCARAI 295
+ A++ WHP+ F C CG GF + G+A CR+ A C C I
Sbjct: 3 IKAMNSAWHPQCFLCQLCGTCMADSGFVKNAGRALCRECNAKEKARGTGKYVCHKCHDVI 182
Query: 296 -LENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGS-LCSGCQKP 353
+ +I +HP F C C +N E D + YC + H++ G +C C++P
Sbjct: 183 EMNGHIKFRGEAYHPYHFNCHSCGVE-LNTEAREKDSELYC-LRCHDKMGIPICGACRRP 356
Query: 354 ITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 402
I R + A+ K +H EHFVCA C K E+ YC+ + +LF
Sbjct: 357 IEERVVHALGKAWHVEHFVCAKCEKPFLGTRHYEKKGLAYCEIHYHQLF 503
>14307
Length = 816
Score = 86.7 bits (213), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 62/214 (28%), Positives = 91/214 (42%), Gaps = 13/214 (6%)
Frame = +2
Query: 156 DLNKLGVATVAKG----VCGACKKPIAGQ--VVTA----MGKTWHPEHFVCTHCQEEIGS 205
D + V +V + C CK I VVTA G WHP FVC+ C+E +
Sbjct: 125 DQVAMDVGSVKEAPSDTTCHCCKGEIDKLELVVTAPKVGEGTVWHPACFVCSTCEELLVD 304
Query: 206 RNFFERDGQPYCEKDYHNLFSPRCYYCNGPILD-KVVTALDRTWHPEHFFCAQCGAFFGP 264
+ + D YC++ Y L PRC C+ I + A++ +H +H C QC
Sbjct: 305 LVYCQHDKHLYCQRHYAELIRPRCPGCDELIFSGEYTKAMEECYHKDHLACWQCDKQLVS 484
Query: 265 EGFHEKDGKAYCRKDYFDMFAPKCGGCARAILENY--ISALNTLWHPECFVCRECFTPFV 322
+ +D +C Y +FA KC C + I +Y +S + WH CF C C V
Sbjct: 485 CRYIMRDDHPHCVPCYQALFANKCEDCDKPIGPDYKDLSYKDKHWHEFCFKCTMCDKSLV 664
Query: 323 NGSFFEHDGQPYCEVHYHERRGSLCSGCQKPITG 356
+ F + + +C Y + C GC P G
Sbjct: 665 DQPFAPKNEKIFCSECYDNSFAARCDGCGNPFKG 766
Score = 79.0 bits (193), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 52/183 (28%), Positives = 78/183 (42%), Gaps = 9/183 (4%)
Frame = +2
Query: 229 CYYCNGPI--LDKVVTA----LDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFD 282
C+ C G I L+ VVTA WHP F C+ C + + D YC++ Y +
Sbjct: 179 CHCCKGEIDKLELVVTAPKVGEGTVWHPACFVCSTCEELLVDLVYCQHDKHLYCQRHYAE 358
Query: 283 MFAPKCGGCARAILE-NYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHE 341
+ P+C GC I Y A+ +H + C +C V+ + D P+C Y
Sbjct: 359 LIRPRCPGCDELIFSGEYTKAMEECYHKDHLACWQCDKQLVSCRYIMRDDHPHCVPCYQA 538
Query: 342 RRGSLCSGCQKPI--TGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFL 399
+ C C KPI + ++ K +H F C C K L F +N+K +C C+
Sbjct: 539 LFANKCEDCDKPIGPDYKDLSYKDKHWHEFCFKCTMCDKSLVDQPFAPKNEKIFCSECYD 718
Query: 400 KLF 402
F
Sbjct: 719 NSF 727
>05726
Length = 733
Score = 74.3 bits (181), Expect = 9e-14, Method: Compositional matrix adjust.
Identities = 42/135 (31%), Positives = 61/135 (45%), Gaps = 4/135 (2%)
Frame = +1
Query: 205 SRNFFERDGQPYCEKDYHNLFSPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGP 264
+++F RD + C Y N ++ RC+ C+ I ++ + WH E F C C
Sbjct: 1 NKSFIPRDDRVICVPCYENNYAQRCFKCSQVINKGGISYKNTPWHRECFTCTHCDKMLAG 180
Query: 265 EGFHEKDGKAYCRKDYFDMFAPKCGGCARAIL----ENYISALNTLWHPECFVCRECFTP 320
E F KD + YC + D+FA KC C +AI +IS WH +CF C +C
Sbjct: 181 EKFTSKDDQPYCGDCFGDLFAKKCCRCQKAITGIGGTKFISFEERHWHSDCFTCFKCQAS 360
Query: 321 FVNGSFFEHDGQPYC 335
V F +D C
Sbjct: 361 MVGRGFLMNDDDIVC 405
Score = 63.5 bits (153), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 41/137 (29%), Positives = 60/137 (43%), Gaps = 4/137 (2%)
Frame = +1
Query: 265 EGFHEKDGKAYCRKDYFDMFAPKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNG 324
+ F +D + C Y + +A +C C++ I + IS NT WH ECF C C
Sbjct: 4 KSFIPRDDRVICVPCYENNYAQRCFKCSQVINKGGISYKNTPWHRECFTCTHCDKMLAGE 183
Query: 325 SFFEHDGQPYCEVHYHERRGSLCSGCQKPITG----RCITAMAKKFHPEHFVCAFCLKQL 380
F D QPYC + + C CQK ITG + I+ + +H + F C C +
Sbjct: 184 KFTSKDDQPYCGDCFGDLFAKKCCRCQKAITGIGGTKFISFEERHWHSDCFTCFKCQASM 363
Query: 381 NKGTFKEQNDKPYCQNC 397
F +D C +C
Sbjct: 364 VGRGFLMNDDDIVCPDC 414
Score = 63.2 bits (152), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 34/111 (30%), Positives = 49/111 (44%), Gaps = 4/111 (3%)
Frame = +1
Query: 170 CGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRC 229
C C + I ++ WH E F CTHC + + F +D QPYC + +LF+ +C
Sbjct: 73 CFKCSQVINKGGISYKNTPWHRECFTCTHCDKMLAGEKFTSKDDQPYCGDCFGDLFAKKC 252
Query: 230 YYCNGPIL----DKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYC 276
C I K ++ +R WH + F C +C A GF D C
Sbjct: 253 CRCQKAITGIGGTKFISFEERHWHSDCFTCFKCQASMVGRGFLMNDDDIVC 405
Score = 43.5 bits (101), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 26/80 (32%), Positives = 34/80 (42%)
Frame = +1
Query: 323 NGSFFEHDGQPYCEVHYHERRGSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNK 382
N SF D + C Y C C + I I+ +H E F C C K L
Sbjct: 1 NKSFIPRDDRVICVPCYENNYAQRCFKCSQVINKGGISYKNTPWHRECFTCTHCDKMLAG 180
Query: 383 GTFKEQNDKPYCQNCFLKLF 402
F ++D+PYC +CF LF
Sbjct: 181 EKFTSKDDQPYCGDCFGDLF 240
>34420
Length = 719
Score = 43.9 bits (102), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 24/74 (32%), Positives = 34/74 (45%), Gaps = 4/74 (5%)
Frame = +2
Query: 207 NFFERDGQPYCEKDYHNLFSPRCYYCNGPIL----DKVVTALDRTWHPEHFFCAQCGAFF 262
F +D QPYC + LF+ RC C PI K ++ +R WH + F C +C A
Sbjct: 5 KFTSKDEQPYCGDCFGELFAKRCIRCTQPITGIGGTKFISFEERHWHSDCFVCYRCNASM 184
Query: 263 GPEGFHEKDGKAYC 276
GF + + C
Sbjct: 185 VGRGFLMQGEEILC 226
Score = 39.3 bits (90), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 23/75 (30%), Positives = 32/75 (42%), Gaps = 4/75 (5%)
Frame = +2
Query: 265 EGFHEKDGKAYCRKDYFDMFAPKCGGCARAIL----ENYISALNTLWHPECFVCRECFTP 320
E F KD + YC + ++FA +C C + I +IS WH +CFVC C
Sbjct: 2 EKFTSKDEQPYCGDCFGELFAKRCIRCTQPITGIGGTKFISFEERHWHSDCFVCYRCNAS 181
Query: 321 FVNGSFFEHDGQPYC 335
V F + C
Sbjct: 182 MVGRGFLMQGEEILC 226
Score = 34.7 bits (78), Expect = 0.067, Method: Compositional matrix adjust.
Identities = 23/76 (30%), Positives = 34/76 (44%), Gaps = 4/76 (5%)
Frame = +2
Query: 326 FFEHDGQPYCEVHYHERRGSLCSGCQKPITG----RCITAMAKKFHPEHFVCAFCLKQLN 381
F D QPYC + E C C +PITG + I+ + +H + FVC C +
Sbjct: 8 FTSKDEQPYCGDCFGELFAKRCIRCTQPITGIGGTKFISFEERHWHSDCFVCYRCNASMV 187
Query: 382 KGTFKEQNDKPYCQNC 397
F Q ++ C +C
Sbjct: 188 GRGFLMQGEEILCPDC 235
Score = 28.5 bits (62), Expect = 4.7, Method: Compositional matrix adjust.
Identities = 14/52 (26%), Positives = 23/52 (44%), Gaps = 4/52 (7%)
Frame = +2
Query: 170 CGACKKPIAG----QVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYC 217
C C +PI G + ++ + WH + FVC C + R F + + C
Sbjct: 71 CIRCTQPITGIGGTKFISFEERHWHSDCFVCYRCNASMVGRGFLMQGEEILC 226
>26762
Length = 399
Score = 42.7 bits (99), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 23/66 (34%), Positives = 32/66 (48%), Gaps = 4/66 (6%)
Frame = +1
Query: 206 RNFFERDGQPYCEKDYHNLFSPRCYYCNGPIL----DKVVTALDRTWHPEHFFCAQCGAF 261
+ F RD +PYC + LF+ RC C PI + ++ +R WH + F CA C A
Sbjct: 1 QRFTSRDEKPYCAECLGELFAKRCTSCVKPITGIGGTRFISFEERHWHHDCFVCASCKAS 180
Query: 262 FGPEGF 267
GF
Sbjct: 181 LVGRGF 198
Score = 38.9 bits (89), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 21/65 (32%), Positives = 29/65 (44%), Gaps = 4/65 (6%)
Frame = +1
Query: 267 FHEKDGKAYCRKDYFDMFAPKCGGCARAIL----ENYISALNTLWHPECFVCRECFTPFV 322
F +D K YC + ++FA +C C + I +IS WH +CFVC C V
Sbjct: 7 FTSRDEKPYCAECLGELFAKRCTSCVKPITGIGGTRFISFEERHWHHDCFVCASCKASLV 186
Query: 323 NGSFF 327
F
Sbjct: 187 GRGFI 201
Score = 37.0 bits (84), Expect = 0.016, Method: Compositional matrix adjust.
Identities = 25/76 (32%), Positives = 32/76 (42%), Gaps = 4/76 (5%)
Frame = +1
Query: 326 FFEHDGQPYCEVHYHERRGSLCSGCQKPITG----RCITAMAKKFHPEHFVCAFCLKQLN 381
F D +PYC E C+ C KPITG R I+ + +H + FVCA C L
Sbjct: 7 FTSRDEKPYCAECLGELFAKRCTSCVKPITGIGGTRFISFEERHWHHDCFVCASCKASLV 186
Query: 382 KGTFKEQNDKPYCQNC 397
F C +C
Sbjct: 187 GRGFITDGPDILCPDC 234
Score = 30.0 bits (66), Expect = 1.9, Method: Compositional matrix adjust.
Identities = 14/44 (31%), Positives = 22/44 (50%), Gaps = 4/44 (9%)
Frame = +1
Query: 170 CGACKKPIAG----QVVTAMGKTWHPEHFVCTHCQEEIGSRNFF 209
C +C KPI G + ++ + WH + FVC C+ + R F
Sbjct: 70 CTSCVKPITGIGGTRFISFEERHWHHDCFVCASCKASLVGRGFI 201
>05103
Length = 1504
Score = 37.7 bits (86), Expect = 0.008, Method: Compositional matrix adjust.
Identities = 17/56 (30%), Positives = 23/56 (41%)
Frame = +2
Query: 287 KCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHER 342
+CGGC + A +H CF C C FF D + YCE H ++
Sbjct: 641 RCGGCDMLATGVIVKANGVPYHVACFKCESCSMNLKQKGFFVVDDKLYCETHARQK 808
Score = 35.0 bits (79), Expect = 0.051, Method: Compositional matrix adjust.
Identities = 17/49 (34%), Positives = 22/49 (44%)
Frame = +2
Query: 170 CGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCE 218
CG C G +V A G +H F C C + + FF D + YCE
Sbjct: 644 CGGCDMLATGVIVKANGVPYHVACFKCESCSMNLKQKGFFVVDDKLYCE 790
Score = 28.9 bits (63), Expect = 3.7, Method: Compositional matrix adjust.
Identities = 16/49 (32%), Positives = 21/49 (42%)
Frame = +2
Query: 347 CSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQ 395
C GC TG + A +H F C C L + F +DK YC+
Sbjct: 644 CGGCDMLATGVIVKANGVPYHVACFKCESCSMNLKQKGFFVVDDKLYCE 790
>30169
Length = 426
Score = 35.0 bits (79), Expect = 0.047, Method: Compositional matrix adjust.
Identities = 18/61 (29%), Positives = 28/61 (45%), Gaps = 1/61 (1%)
Frame = -1
Query: 169 VCGACKKPIA-GQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSP 227
+C C K + + V MGK +H F CT C++ + S + YC+ Y F P
Sbjct: 408 MCAVCGKAVYFAERVAGMGKVYHKACFKCTSCRKILDSTLLTQHQDNIYCKACYGKNFGP 229
Query: 228 R 228
+
Sbjct: 228 K 226
Score = 32.0 bits (71), Expect = 0.41, Method: Compositional matrix adjust.
Identities = 17/58 (29%), Positives = 26/58 (44%), Gaps = 1/58 (1%)
Frame = -1
Query: 346 LCSGCQKPIT-GRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 402
+C+ C K + + M K +H F C C K L+ + D YC+ C+ K F
Sbjct: 408 MCAVCGKAVYFAERVAGMGKVYHKACFKCTSCRKILDSTLLTQHQDNIYCKACYGKNF 235
Score = 28.1 bits (61), Expect = 6.8, Method: Compositional matrix adjust.
Identities = 13/58 (22%), Positives = 24/58 (41%), Gaps = 1/58 (1%)
Frame = -1
Query: 288 CGGCARAI-LENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRG 344
C C +A+ ++ + ++H CF C C + +H YC+ Y + G
Sbjct: 405 CAVCGKAVYFAERVAGMGKVYHKACFKCTSCRKILDSTLLTQHQDNIYCKACYGKNFG 232
>15283
Length = 402
Score = 29.3 bits (64), Expect = 3.1, Method: Compositional matrix adjust.
Identities = 15/43 (34%), Positives = 21/43 (48%)
Frame = +1
Query: 346 LCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQ 388
LC C + C+T KK +VC C+K +K FK+Q
Sbjct: 199 LCDKCPRSYHLHCVTPPLKKVPKGKWVCPVCVKSKSKKGFKQQ 327
>17933
Length = 842
Score = 28.9 bits (63), Expect = 3.6, Method: Compositional matrix adjust.
Identities = 13/33 (39%), Positives = 21/33 (63%)
Frame = +1
Query: 291 CARAILENYISALNTLWHPECFVCRECFTPFVN 323
C+ +++E + NT++ CFV +CFT FVN
Sbjct: 613 CSNSLVEL*MFGYNTIFFLSCFVN*KCFTLFVN 711
>32935
Length = 1188
Score = 27.7 bits (60), Expect = 9.6, Method: Compositional matrix adjust.
Identities = 29/101 (28%), Positives = 40/101 (39%), Gaps = 2/101 (1%)
Frame = +1
Query: 16 PSRKEATPEGRPETCLLPSSPQAQRP--IQGLEQRADGERCWAAGWPRDGGRSSPGGQDE 73
P+ +A P+ RP +LP +PQ P + GL + W +G + GR GG +
Sbjct: 370 PANVQAGPQHRP--GVLPGAPQQALPQCVVGLRNK------WTSGGL*NSGRERGGGVER 525
Query: 74 GGGSWPXXXXXXXXXXXXXXXXGEKYPHPCAARHRTPSLRS 114
G WP + HPC RHR RS
Sbjct: 526 G--HWPH*PLPRPQRG--------THQHPCTVRHRRNVQRS 618
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000221413 | hsapiens_gene_ensembl | RuvB-like 2
(EC 3.6.1.-) (48 kDa TATA box-binding protein-interacting protein) (48
kDa TBP-interacting protein) (TIP49b) (Repressing pontin 52) (Reptin
52) (51 kDa erythrocyte cytosolic protein) (ECP-51) (TIP60-associated
protein 54-beta) (TAP54-beta). [Source:Uniprot/SWISSPROT;Acc:Q9Y230]
(463 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
01279 201 4e-91
23413 323 9e-89
39786 70 2e-26
14389 102 2e-22
23766 33 0.33
19129 31 1.1
17843 31 1.4
07243 30 1.5
20339 29 3.6
13144 28 7.5
>01279
Length = 2183
Score = 201 bits (510), Expect(3) = 4e-91, Method: Compositional matrix adjust.
Identities = 100/226 (44%), Positives = 154/226 (68%), Gaps = 8/226 (3%)
Frame = -2
Query: 234 KRKEVVHTVSLHEIDVINSRTQG-------FLALFSGDTGEIKSEVREQINAKVAEWREE 286
++KEV+ V+LH++DV N+R QG L EI ++R++IN V ++ ++
Sbjct: 1417 QKKEVIQDVTLHDLDVANARPQGGQDIMSMMGQLMKPKKTEITDKLRKEINKVVNKYIDQ 1238
Query: 287 GKAEIIPGVLFIDEVHMLDIESFSFLNRALESDMAPVLIMATNRGITRIRGT-SYQSPHG 345
G AE++PGVLFIDEVHMLDIE F++L+RALES +AP++I ATNRG I+GT SPHG
Sbjct: 1237 GIAELVPGVLFIDEVHMLDIECFTYLHRALESTIAPIVIFATNRGKCTIKGTEDIISPHG 1058
Query: 346 IPIDLLDRLLIVSTTPYSEKDTKQILRIRCEEEDVEMSEDAYTVLTRIGLETSLRYAIQL 405
+P+DLLDR++IV T PYS+++ QIL+IR + E++++ E++ L IG+ T+LRYA+QL
Sbjct: 1057 MPMDLLDRVMIVRTLPYSQEEMTQILQIRSQTENIQVEEESIQHLGNIGVRTTLRYAVQL 878
Query: 406 ITAASLVCRKRKGTEVQVDDIKRVYSLFLDESRSTQYMKEYQDAFL 451
+T S++ R V ++I+ + LF D S + ++E +D +L
Sbjct: 877 LTPGSILARINGKDNVGKEEIEEIDKLFFDAKASAKILQEQEDKYL 740
Score = 146 bits (368), Expect(3) = 4e-91, Method: Compositional matrix adjust.
Identities = 85/201 (42%), Positives = 118/201 (58%), Gaps = 5/201 (2%)
Frame = -3
Query: 41 QASQGMVGQLAARRAAGVVLEMIREGKIAGRAVLIAGQPGTGKTAIAMGMAQALGPDTPF 100
Q+S G+VGQ AR AAGVV+E+I+ K+AGRAVL+AG PGTGKTAIA+ +AQ LG PF
Sbjct: 2004 QSSAGLVGQEGAREAAGVVVELIKTKKMAGRAVLLAGPPGTGKTAIALAIAQELGNKVPF 1825
Query: 101 TAIAGSEIFSLEMSKTEALTQAFRRSIGVRXXXXXXX---XXXXXXXXXXDRPATGTGSK 157
+ GSE++S E+ KTE L + FRR+IG+R + P G G
Sbjct: 1824 CPMVGSEVYSSEIKKTEVLMENFRRAIGLRIKETKEVYEGEVTELTPVETENPMGGYGKT 1645
Query: 158 VGKLT--LKTTEMETIYDLGTKMIESLTKDKVQAGDVITIDKATGKISKLGRSFTRARDY 215
V + LKT + L + ESL K+KV+ GDVI I+ +G + + GRS + A ++
Sbjct: 1644 VSHVVIGLKTAKGTKQLKLDPSIYESLQKEKVEVGDVIYIEANSGAVKRQGRSDSYATEF 1465
Query: 216 DAMGSQTKFVQCPDGELQKRK 236
D + +V P G++ KRK
Sbjct: 1464 DLEAEE--YVPLPKGDVHKRK 1408
Score = 28.1 bits (61), Expect(3) = 4e-91, Method: Compositional matrix adjust.
Identities = 13/33 (39%), Positives = 21/33 (63%), Gaps = 3/33 (9%)
Frame = -1
Query: 4 VTATTKVPEIR---DVTRIERIGAHSHIRGLGL 33
+T +T+ E R + +RI +HSH++GLGL
Sbjct: 2123 LTKSTRKHEDRRSQKYHKAQRIASHSHVKGLGL 2025
>23413
Length = 2343
Score = 323 bits (828), Expect = 9e-89, Method: Compositional matrix adjust.
Identities = 151/182 (82%), Positives = 170/182 (93%), Gaps = 1/182 (0%)
Frame = -3
Query: 283 WREEGKAEIIPGVLFIDEVHMLDIESFSFLNRALESDMAPVLIMATNRGITRIRGTSYQS 342
WREEGKAEI+PGVLFIDEVHMLDIE FSFLNRALE+DMAPVLIMATNRGITRIRGT Y S
Sbjct: 2341 WREEGKAEIVPGVLFIDEVHMLDIECFSFLNRALETDMAPVLIMATNRGITRIRGTHYMS 2162
Query: 343 PHGIPIDLLDRLLIVSTTPYSEKDTKQILRIRCEEEDVEMSEDAYTVLTRIGLETSLRYA 402
PHG+PIDLLDRLLI+STTPY EK+ KQIL+IRCEEEDVEMS+DA TVLT+IG+E SLRY+
Sbjct: 2161 PHGVPIDLLDRLLIISTTPYDEKEIKQILKIRCEEEDVEMSDDALTVLTKIGVEASLRYS 1982
Query: 403 IQLITAASLVCRKRKGTEVQVDDIKRVYSLFLDESRSTQYMKEYQDAFLFNELKG-ETMD 461
IQLITAA+LVCRKRKGTEV+++DIKRVYSLFLDESRSTQ++ EYQ AF+FNE+K E M+
Sbjct: 1981 IQLITAANLVCRKRKGTEVEMEDIKRVYSLFLDESRSTQFLTEYQQAFMFNEVKDQEQME 1802
Query: 462 TS 463
TS
Sbjct: 1801 TS 1796
>39786
Length = 467
Score = 70.5 bits (171), Expect(2) = 2e-26, Method: Compositional matrix adjust.
Identities = 33/41 (80%), Positives = 35/41 (85%)
Frame = +3
Query: 9 KVPEIRDVTRIERIGAHSHIRGLGLDDALEPRQASQGMVGQ 49
K E+RD+TRIERIGAHSHIRGLGLDD LE R SQGMVGQ
Sbjct: 147 KKYEVRDITRIERIGAHSHIRGLGLDDVLEARAVSQGMVGQ 269
Score = 66.6 bits (161), Expect(2) = 2e-26, Method: Compositional matrix adjust.
Identities = 37/65 (56%), Positives = 47/65 (72%), Gaps = 3/65 (4%)
Frame = +1
Query: 52 ARRAAGVVLEMIREGKIAGRAVLIAGQPGT---GKTAIAMGMAQALGPDTPFTAIAGSEI 108
ARRAAGVV++M+REGK R L + K IA+GMAQALG +TPFT+++GSEI
Sbjct: 277 ARRAAGVVVQMVREGK--NRRTLHSTSRRAEYRKKLPIAVGMAQALGTETPFTSMSGSEI 450
Query: 109 FSLEM 113
+SLEM
Sbjct: 451 YSLEM 465
>14389
Length = 790
Score = 102 bits (255), Expect = 2e-22, Method: Compositional matrix adjust.
Identities = 62/169 (36%), Positives = 91/169 (53%), Gaps = 5/169 (2%)
Frame = +3
Query: 81 TGKTAIAMGMAQALGPDTPFTAIAGSEIFSLEMSKTEALTQAFRRSIGVRXXXXXXX--- 137
TGKTAIA+ +AQ LG PF + GSE+FS E+ KTE L + FRRSIG+R
Sbjct: 3 TGKTAIALAIAQELGNKVPFCPMVGSEVFSNEIKKTEVLMENFRRSIGLRIRETKEVYEG 182
Query: 138 XXXXXXXXXXDRPATGTGSKVGKLT--LKTTEMETIYDLGTKMIESLTKDKVQAGDVITI 195
+ P G G + + LKT + L + ++L K+KV+ GDVI I
Sbjct: 183 EVTELTPVETENPMGGYGKTISNVVIGLKTAKGTKQLKLDPSIFDALQKEKVEVGDVIYI 362
Query: 196 DKATGKISKLGRSFTRARDYDAMGSQTKFVQCPDGELQKRKEVVHTVSL 244
+ +G + + GRS T A ++D ++V P G++ K+KEV+ V+L
Sbjct: 363 EANSGAVKRQGRSDTFATEFDL--ETEEYVPLPKGDVHKKKEVIQDVTL 503
Score = 73.6 bits (179), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 33/87 (37%), Positives = 58/87 (66%)
Frame = +3
Query: 362 YSEKDTKQILRIRCEEEDVEMSEDAYTVLTRIGLETSLRYAIQLITAASLVCRKRKGTEV 421
YS D +QI+++R + E +++ E+A++ L+ IG ++LRYA+QL+T A +C+ +
Sbjct: 507 YSTSDMEQIIKLRAQTEGLQLEENAFSRLSEIGTSSTLRYAVQLLTPAYQMCKVNGRNLI 686
Query: 422 QVDDIKRVYSLFLDESRSTQYMKEYQD 448
DDI V+SLFLD RS++++ E +
Sbjct: 687 SKDDIDDVHSLFLDAKRSSKHLSEKNN 767
>23766
Length = 1463
Score = 32.7 bits (73), Expect = 0.33, Method: Compositional matrix adjust.
Identities = 17/46 (36%), Positives = 25/46 (54%)
Frame = +1
Query: 64 REGKIAGRAVLIAGQPGTGKTAIAMGMAQALGPDTPFTAIAGSEIF 109
R+G A + V++ G PGTGKT +A +A F + GSE+
Sbjct: 136 RDGNQAPKGVILYGPPGTGKTLLAKAVANQTS--ATFLRVVGSELI 267
>19129
Length = 1020
Score = 30.8 bits (68), Expect = 1.1, Method: Compositional matrix adjust.
Identities = 15/38 (39%), Positives = 23/38 (60%)
Frame = +1
Query: 71 RAVLIAGQPGTGKTAIAMGMAQALGPDTPFTAIAGSEI 108
+ VL+ G PGTGKT +A +A + F ++GSE+
Sbjct: 592 KGVLLYGPPGTGKTLLARAVAHHT--ECTFIRVSGSEL 699
>17843
Length = 772
Score = 30.8 bits (68), Expect = 1.4, Method: Compositional matrix adjust.
Identities = 11/25 (44%), Positives = 15/25 (60%)
Frame = +1
Query: 70 GRAVLIAGQPGTGKTAIAMGMAQAL 94
R +L+ G PGTGKT + +A L
Sbjct: 184 NRVILLHGPPGTGKTTLCKALAHKL 258
>07243
Length = 1112
Score = 30.4 bits (67), Expect = 1.5, Method: Compositional matrix adjust.
Identities = 17/47 (36%), Positives = 23/47 (48%)
Frame = +1
Query: 62 MIREGKIAGRAVLIAGQPGTGKTAIAMGMAQALGPDTPFTAIAGSEI 108
+R G + L+ G PGTGKT +A +A L D F + S I
Sbjct: 283 FLRVGITPPKGCLLYGPPGTGKTLLARAVASQL--DANFLKVVSSAI 417
>20339
Length = 470
Score = 29.3 bits (64), Expect = 3.6, Method: Compositional matrix adjust.
Identities = 19/58 (32%), Positives = 28/58 (48%)
Frame = +2
Query: 155 GSKVGKLTLKTTEMETIYDLGTKMIESLTKDKVQAGDVITIDKATGKISKLGRSFTRA 212
G + G L+LKT + DL K+IESL D I++ K+ K+ F R+
Sbjct: 281 GFQKGALSLKTATQSAVLDLLKKLIESLLVCSEFCFDFFVIEQ---KLQKIPSXFKRS 445
>13144
Length = 457
Score = 28.1 bits (61), Expect = 7.5, Method: Composition-based stats.
Identities = 9/31 (29%), Positives = 21/31 (67%)
Frame = +1
Query: 154 TGSKVGKLTLKTTEMETIYDLGTKMIESLTK 184
+GS++GK+ ++ ++ E + GTK++E +
Sbjct: 283 SGSQIGKINIRASQQEEFFAHGTKLLEPFEQ 375
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000318315 | hsapiens_gene_ensembl | Protein kinase
C beta type (EC 2.7.11.13) (PKC-beta) (PKC-B).
[Source:Uniprot/SWISSPROT;Acc:P05771]
(671 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
18484 275 2e-89
30755 229 2e-60
18663 190 1e-48
03240 169 3e-42
25445 162 3e-40
00486 143 3e-34
26156 117 6e-32
17722 114 1e-25
27405 113 2e-25
31885 110 2e-24
25019 80 9e-24
12721 104 1e-22
26560 102 3e-22
06405 100 2e-21
09606 97 3e-20
13066 92 5e-19
15910 92 6e-19
18921 91 1e-18
14420 91 2e-18
00300 89 6e-18
21808 84 1e-16
01707 83 4e-16
01392 80 3e-15
21079 77 3e-14
13592 76 5e-14
16549 73 5e-13
01060 72 6e-13
14116 72 1e-12
13212 70 2e-12
00392 69 6e-12
14126 69 7e-12
04852 68 1e-11
19094 68 2e-11
32957 67 3e-11
29581 65 6e-11
27546 65 8e-11
09007 63 5e-10
28638 51 6e-10
38560 62 1e-09
04591 60 2e-09
21433 60 2e-09
26711 60 3e-09
07940 60 3e-09
37602 60 3e-09
11185 60 4e-09
35187 59 8e-09
12672 58 1e-08
29179 58 1e-08
01756 58 1e-08
17300 57 2e-08
01966 49 3e-08
19761 55 6e-08
07291 55 6e-08
17932 42 6e-08
11780 50 7e-08
17591 55 8e-08
00715 55 8e-08
33586 47 8e-08
11353 55 1e-07
29590 55 1e-07
31935 54 2e-07
03508 54 3e-07
12786 54 3e-07
30339 53 5e-07
19361 52 1e-06
17975 51 2e-06
30040 50 3e-06
22804 50 4e-06
01718 49 8e-06
26525 49 1e-05
20640 47 3e-05
19301 47 3e-05
20152 46 4e-05
04138 46 4e-05
07833 45 9e-05
07591 45 1e-04
30743 45 1e-04
27274 44 2e-04
16708 44 3e-04
03942 41 0.002
36305 41 0.002
18996 40 0.002
07836 40 0.003
02638 38 0.011
12442 37 0.031
14477 36 0.040
11404 36 0.041
18401 36 0.065
31120 34 0.15
22005 34 0.15
17253 33 0.27
13896 33 0.37
17516 33 0.39
26009 33 0.49
02913 33 0.52
13305 32 0.63
26052 32 0.71
29360 32 0.88
17637 31 1.9
33692 30 3.8
36976 29 5.1
36388 29 5.6
26304 29 7.5
08416 28 9.2
>18484
Length = 635
Score = 275 bits (704), Expect(2) = 2e-89, Method: Compositional matrix adjust.
Identities = 126/161 (78%), Positives = 143/161 (88%)
Frame = +1
Query: 427 DLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFG 486
DLMY IQQ G+FKEP A FYAAEIA+GLFFL +GIIYRDLKLDNVMLDSEGHIKIADFG
Sbjct: 1 DLMYRIQQEGKFKEPVAAFYAAEIAVGLFFLHDQGIIYRDLKLDNVMLDSEGHIKIADFG 180
Query: 487 MCKENIWDGVTTKTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDE 546
MCKE + TT+TFCGTPDYIAPEI+ YQPY KSVDWWA+GVLL+EMLAGQ PF+GEDE
Sbjct: 181 MCKEGMTGDATTRTFCGTPDYIAPEIVLYQPYSKSVDWWAYGVLLFEMLAGQPPFDGEDE 360
Query: 547 DELFQSIMEHNVAYPKSMSKEAVAICKGLMTKHPGKRLGCG 587
DELF SI +HNV+YPK+MS+EAV++CKGL+ K+P KRLGCG
Sbjct: 361 DELFSSITDHNVSYPKAMSREAVSLCKGLLMKNPTKRLGCG 483
Score = 72.8 bits (177), Expect(2) = 2e-89, Method: Compositional matrix adjust.
Identities = 32/53 (60%), Positives = 39/53 (73%)
Frame = +2
Query: 584 LGCGPEGERDIKEHAFFRYIDWEKLERKEIQPPYKPKARDKRDTSNFDKEFTR 636
LG GERDI++HAFFR I W+K++ E+QPPYKPK D+R NFDK FTR
Sbjct: 473 LGVVQNGERDIRDHAFFRRIVWDKIKSMEVQPPYKPKITDRRKAENFDKSFTR 631
>30755
Length = 1137
Score = 229 bits (584), Expect = 2e-60, Method: Compositional matrix adjust.
Identities = 106/215 (49%), Positives = 147/215 (68%)
Frame = +2
Query: 431 HIQQVGRFKEPHAVFYAAEIAIGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCKE 490
H+ F E FY AEI L +L S+GIIYRDLKL+N++LD +GHIK+ADFG+CKE
Sbjct: 2 HLSHERIFTEERTRFYGAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCKE 181
Query: 491 NIWDGVTTKTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELF 550
+I G TTKTFCGTP+Y+APE++ YG++VDWW GV++YEM+ G+ PF D D LF
Sbjct: 182 DITYGRTTKTFCGTPEYLAPEVLDDNDYGRAVDWWGTGVVMYEMICGRLPFYNRDHDVLF 361
Query: 551 QSIMEHNVAYPKSMSKEAVAICKGLMTKHPGKRLGCGPEGERDIKEHAFFRYIDWEKLER 610
I+ +V +P++++ EA ++ GL+ K P RLG G + ++I+ H FF I+W L +
Sbjct: 362 TLILVEDVKFPRNITDEAKSLLSGLLAKDPRNRLGGGQDDVKEIQAHPFFASINWTDLVQ 541
Query: 611 KEIQPPYKPKARDKRDTSNFDKEFTRQPVELTPTD 645
K+I PP+KP+ DT FD+EFT + VELTP D
Sbjct: 542 KKITPPFKPQVTSDTDTRYFDEEFTGESVELTPPD 646
>18663
Length = 600
Score = 190 bits (483), Expect = 1e-48, Method: Compositional matrix adjust.
Identities = 94/177 (53%), Positives = 119/177 (67%), Gaps = 10/177 (5%)
Frame = +2
Query: 499 KTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAPF------EGED---EDEL 549
TFCGTP+YIAPEI+ + YG SVDWWA GVLLYEMLAG++PF E D ED L
Sbjct: 2 STFCGTPNYIAPEILRGEDYGFSVDWWALGVLLYEMLAGRSPFDIAGASENPDQNTEDYL 181
Query: 550 FQSIMEHNVAYPKSMSKEAVAICKGLMTKHPGKRLGCGPEGE-RDIKEHAFFRYIDWEKL 608
FQ I+E + P+S+S +A ++ KG + K+P RLGC E DI H FF+ IDWE L
Sbjct: 182 FQVILEKTIRIPRSLSVKAASVLKGFLNKNPADRLGCHRESAFMDIVNHPFFKVIDWEML 361
Query: 609 ERKEIQPPYKPKARDKRDTSNFDKEFTRQPVELTPTDKLFIMNLDQNEFAGFSYTNP 665
ERK++ PP+KP+ RD +NF EFT +PV+LTP D I ++DQ+EF GF Y NP
Sbjct: 362 ERKQVSPPFKPRLDSDRDLANFPIEFTGEPVQLTPDDDHVIDSIDQSEFEGFEYVNP 532
>03240
Length = 1683
Score = 169 bits (429), Expect = 3e-42, Method: Compositional matrix adjust.
Identities = 120/389 (30%), Positives = 176/389 (45%), Gaps = 55/389 (14%)
Frame = -3
Query: 298 NEELRQKFERAKISQGTKVPEEKTTNTVSKFDNNGNRDRMKLTDFNFLMVLGKGSFGKVM 357
NE + K Q ++ +K +N + R +M F + LG G+FG+V
Sbjct: 1402 NEMAKVKLSEEAARQMRRMLHQKESNYIRL-----KRAKMDKCMFEKIKTLGVGAFGEVS 1238
Query: 358 LSERKGTDELYAVKILKKDVVIQDDDVECTMVEKRVLALPGKPPFLTQLHSCFQTMDRLY 417
L + T LYA+K L+K V++ + V E+ +LA ++ +L+ FQ + LY
Sbjct: 1237 LCRKNDTGMLYAMKTLRKSDVLKRNQVAHVKAERDILA-EADNEWVVKLYYSFQDHNYLY 1061
Query: 418 FVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSKGIIYRDLKLDNVMLDSE 477
FVM+YV GGDLM + ++ EP A FY AE+ + + G I+RD+K DN+++D
Sbjct: 1060 FVMDYVPGGDLMGLLIRMEILDEPLARFYVAELVQAIESVHRMGFIHRDIKPDNILIDRN 881
Query: 478 GHIKIADFGMCKENIW---------DGVTTK----------------------------- 499
GHIK+ DFG+C W DG +
Sbjct: 880 GHIKLTDFGLCTGFRWTHNSKYYQRDGTHARQDSMEVKCQLDEQCQCEILKPLERRRKRE 701
Query: 500 ------TFCGTPDYIAPEIIA-YQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQS 552
+ GTP+YIAPE+++ Y DWW+ GV+L+EML G PF E
Sbjct: 700 QRCLAHSLVGTPNYIAPEVLSRLGGYTSVCDWWSVGVILFEMLVGHPPFYANTPAE---- 533
Query: 553 IMEHNVAYPKSMSKEAVAICKGLMTKHPGK----RLGCGPE------GERDIKEHAFFRY 602
Y K+ + I + P K RL CG + G +IK H FF
Sbjct: 532 -----TQYKVINWKDMLKIPRESNLSQPAKDLILRLCCGSDDRLGLNGAGEIKTHMFFAG 368
Query: 603 IDWEKLERKEIQPPYKPKARDKRDTSNFD 631
+++E L ++ QPPY P R DTSNFD
Sbjct: 367 VNFETLRKQ--QPPYVPNIRYATDTSNFD 287
>25445
Length = 460
Score = 162 bits (411), Expect = 3e-40, Method: Compositional matrix adjust.
Identities = 86/162 (53%), Positives = 106/162 (65%), Gaps = 12/162 (7%)
Frame = -1
Query: 80 EFVTFSCPGADKGPASDDPRSKHKFKIHTYSSPTFCDHCGSLLYGLIHQGMKCDTCMMNV 139
EFV+F+CPGAD GP SD + HKFK HTY SPTFCDHCGSLLYGLIHQG+KCD+C MN
Sbjct: 460 EFVSFACPGADNGPDSDA-TNLHKFKAHTYGSPTFCDHCGSLLYGLIHQGLKCDSCDMNC 284
Query: 140 HKRCVMNVPSLCGTDHTERRGRIYIQAHIDRDVLIVLVRDAKNLVPMDPNGLSDPYVKL- 198
HKRC +VP LCG DHTERRGRIY++ L+V V++AK P++++
Sbjct: 283 HKRCEKHVPRLCGMDHTERRGRIYLRISPHGSKLLVNVKEAKKPC--------VPWIQMV 128
Query: 199 -----------KLIPDPKSESKQKTKTIKCSLNPEWNETFRF 229
+IP ++E TKTIK SLNP+W+ETF
Sbjct: 127 WPILIPK*S*FHMIPTKQTE----TKTIKSSLNPQWDETFTL 14
Score = 55.1 bits (131), Expect = 1e-07, Method: Composition-based stats.
Identities = 26/69 (37%), Positives = 32/69 (46%)
Frame = -1
Query: 18 VRFARKGALRQKNVHEVKNHKFTARFFKQPTFCSHCTDFIWGFGKQGFQCQVCCFVVHKR 77
V FA GA + HKF A + PTFC HC ++G QG +C C HKR
Sbjct: 454 VSFACPGADNGPDSDATNLHKFKAHTYGSPTFCDHCGSLLYGLIHQGLKCDSCDMNCHKR 275
Query: 78 CHEFVTFSC 86
C + V C
Sbjct: 274 CEKHVPRLC 248
>00486
Length = 797
Score = 143 bits (360), Expect = 3e-34, Method: Compositional matrix adjust.
Identities = 67/174 (38%), Positives = 101/174 (58%)
Frame = -2
Query: 498 TKTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHN 557
T TFCGT +Y+APEI+ +GK+VDWW+ G L+Y+ML G PF E+ + I++
Sbjct: 787 THTFCGTIEYMAPEILTRTGHGKAVDWWSLGALMYDMLTGSPPFTAENRKKTIDKILKGK 608
Query: 558 VAYPKSMSKEAVAICKGLMTKHPGKRLGCGPEGERDIKEHAFFRYIDWEKLERKEIQPPY 617
+ P ++ EA + K L+ K+P +RLG G + IK+H FFR +W L + +PP+
Sbjct: 607 LNLPPYLTNEARGLIKKLLRKNPAERLGGGHDDSGPIKDHQFFRNTNWALLALRRAEPPF 428
Query: 618 KPKARDKRDTSNFDKEFTRQPVELTPTDKLFIMNLDQNEFAGFSYTNPEFVINV 671
+P DTS FD +FTRQ +P D + +++Q F GF+Y P + V
Sbjct: 427 RPNVTSDEDTSQFDTKFTRQTPVDSPDDTILSDSINQ-VFKGFTYIAPSVLEEV 269
>26156
Length = 479
Score = 117 bits (292), Expect(2) = 6e-32, Method: Compositional matrix adjust.
Identities = 54/112 (48%), Positives = 77/112 (68%)
Frame = -1
Query: 334 RDRMKLTDFNFLMVLGKGSFGKVMLSERKGTDELYAVKILKKDVVIQDDDVECTMVEKRV 393
R+++ LTDF L V+G+GS+ KV+ E K T +YA+K++KK++V D+D++ EK V
Sbjct: 407 RNKLGLTDFLLLRVIGRGSYAKVLQVEHKRTKRIYAMKVIKKELVNDDEDIDWVQTEKHV 228
Query: 394 LALPGKPPFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVF 445
PFL LHSCFQ+ RL+FV+E+VNGGDLM+H+Q+ R E HA F
Sbjct: 227 FETATNYPFLVGLHSCFQSESRLFFVIEFVNGGDLMFHMQRQRRLPEEHARF 72
Score = 39.7 bits (91), Expect(2) = 6e-32, Method: Composition-based stats.
Identities = 16/25 (64%), Positives = 20/25 (80%)
Frame = -3
Query: 445 FYAAEIAIGLFFLQSKGIIYRDLKL 469
FY+AEI + L FL +GI+YRDLKL
Sbjct: 75 FYSAEICLALNFLHKRGIVYRDLKL 1
>17722
Length = 680
Score = 114 bits (285), Expect = 1e-25, Method: Compositional matrix adjust.
Identities = 51/122 (41%), Positives = 77/122 (63%)
Frame = -3
Query: 522 VDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHNVAYPKSMSKEAVAICKGLMTKHPG 581
VDWW GV++YEM+ G+ PF D D LF+ I+ NV +P+++S+EA + GL+ K+P
Sbjct: 678 VDWWGTGVVMYEMMCGRLPFYNRDHDVLFELILLQNVKFPRNLSEEAKTLLSGLLAKNPK 499
Query: 582 KRLGCGPEGERDIKEHAFFRYIDWEKLERKEIQPPYKPKARDKRDTSNFDKEFTRQPVEL 641
+RLG +IK H FF+ I+W+ L K+I PP+KP + DT +EF ++ + L
Sbjct: 498 RRLGGSEADVTEIKTHPFFQCINWDDLAAKKITPPWKPDVKSSWDTKYIPEEFAQESLHL 319
Query: 642 TP 643
TP
Sbjct: 318 TP 313
>27405
Length = 532
Score = 113 bits (283), Expect = 2e-25, Method: Compositional matrix adjust.
Identities = 62/178 (34%), Positives = 99/178 (55%), Gaps = 4/178 (2%)
Frame = -3
Query: 352 SFGKVMLSERKGTDELYAVKILKKDVVIQDDDVECTMVEKRVLALPGK---PPFLTQLHS 408
FG+V + T ++YA+K L K + + E+ +L+L PF+ +
Sbjct: 530 GFGEVYGCRKADTGKMYAMKCLDKKRIKMKGGETLALNERIMLSLVSTGEGSPFIVCMTY 351
Query: 409 CFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSKGIIYRDLK 468
FQT ++L F+++ +NGGDL YH+ Q G F E FYAAE+ +GL + S+ ++YRDLK
Sbjct: 350 AFQTPEKLCFILDLMNGGDLHYHLSQHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLK 171
Query: 469 LDNVMLDSEGHIKIADFGMCKENIWDGVTTKTFCGTPDYIAPEIIAY-QPYGKSVDWW 525
N++LD GH++I+D G+ + + GT Y+APE++ Q Y S DW+
Sbjct: 170 PANILLDENGHVRISDLGLACD--FSKKKPHASVGTHGYMAPEVLMKGQAYDSSADWF 3
>31885
Length = 529
Score = 110 bits (275), Expect = 2e-24, Method: Compositional matrix adjust.
Identities = 58/146 (39%), Positives = 87/146 (59%), Gaps = 5/146 (3%)
Frame = -2
Query: 401 PFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSK 460
PFL L FQ + L+ V++ GGDL YH+QQ F+E FY ++A+ L +L+S+
Sbjct: 492 PFLVNLWYAFQDEEDLFMVVDLFLGGDLRYHMQQEVSFREDCVKFYLCQLALVLDYLRSQ 313
Query: 461 GIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTKTFCGTPDYIAPEIIAY----- 515
I++RD+K DN++LD +GH + DF + + D + T T GT Y+APE+
Sbjct: 312 KIVHRDIKPDNILLDEQGHCHVTDFNIATQLEDDELATST-SGTRPYMAPEVYGVAINER 136
Query: 516 QPYGKSVDWWAFGVLLYEMLAGQAPF 541
+ YG VDWW+ GV L+E+L + PF
Sbjct: 135 RGYGFPVDWWSLGVSLFELLKKRRPF 58
>25019
Length = 730
Score = 80.5 bits (197), Expect(2) = 9e-24, Method: Compositional matrix adjust.
Identities = 32/59 (54%), Positives = 44/59 (74%)
Frame = +3
Query: 470 DNVMLDSEGHIKIADFGMCKENIWDGVTTKTFCGTPDYIAPEIIAYQPYGKSVDWWAFG 528
+NV+LD +GH+K+ DFG+CKE I T TFCGT +Y+APEI+ +GK+VDWW+ G
Sbjct: 261 ENVLLDKDGHVKLTDFGLCKEAITGTRVTHTFCGTIEYMAPEILTRTGHGKAVDWWSLG 437
Score = 48.5 bits (114), Expect(2) = 9e-24, Method: Compositional matrix adjust.
Identities = 20/59 (33%), Positives = 34/59 (57%)
Frame = +1
Query: 527 FGVLLYEMLAGQAPFEGEDEDELFQSIMEHNVAYPKSMSKEAVAICKGLMTKHPGKRLG 585
+G L+Y+ML G PF E+ + I++ + P ++ EA + K L+ K+P +RLG
Sbjct: 433 WGALMYDMLTGSPPFTAENRKKTIDKILKGKLNLPPYLTNEARGLIKKLLRKNPAERLG 609
>12721
Length = 821
Score = 104 bits (260), Expect = 1e-22, Method: Compositional matrix adjust.
Identities = 49/144 (34%), Positives = 80/144 (55%)
Frame = +1
Query: 401 PFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSK 460
P + ++++ + D L+ VME++ GG L I R E L FL +
Sbjct: 256 PNIVEMYNSYLVNDELWVVMEFMEGGAL-TDIVTNNRMDEVQIATVCRACLKALAFLHAN 432
Query: 461 GIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTKTFCGTPDYIAPEIIAYQPYGK 520
G+I+RD+K D+++L +G +K+ DFG C + D K+ GTP ++APE+I+ PYG
Sbjct: 433 GVIHRDIKSDSILLSHDGKVKLXDFGFCAQVTQDLQKRKSLVGTPYWMAPEVISRLPYGP 612
Query: 521 SVDWWAFGVLLYEMLAGQAPFEGE 544
VD W+ G+++ EM+ + PF E
Sbjct: 613 EVDIWSLGIMVMEMIDAEPPFFNE 684
>26560
Length = 398
Score = 102 bits (255), Expect = 3e-22, Method: Compositional matrix adjust.
Identities = 48/123 (39%), Positives = 75/123 (60%), Gaps = 1/123 (0%)
Frame = -1
Query: 427 DLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFG 486
DL YH+ Q G F E FYAAE+ +GL + S+ ++YRDLK N++LD GH++I+D G
Sbjct: 398 DLHYHLSQHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLG 219
Query: 487 MCKENIWDGVTTKTFCGTPDYIAPEIIAY-QPYGKSVDWWAFGVLLYEMLAGQAPFEGED 545
+ + + GT Y+APE++ Q Y S DW++FG +LY++L G +PF +
Sbjct: 218 LACD--FSKKRPHASVGTHGYMAPEVLMKGQSYDSSADWFSFGCMLYKLLKGHSPFRQHN 45
Query: 546 EDE 548
+ +
Sbjct: 44 QGQ 36
>06405
Length = 1965
Score = 100 bits (250), Expect = 2e-21, Method: Compositional matrix adjust.
Identities = 69/232 (29%), Positives = 116/232 (50%), Gaps = 4/232 (1%)
Frame = +1
Query: 324 TVSKFDNNGNRDRMKLTDFNFLMVLGKGSFGKVMLSERKGTDELYAVKILKKDVVIQDDD 383
TV +R ++ T+ LG G +G V + K +++ AVK LK+D + +D
Sbjct: 211 TVFGVSPEPDRWEIERTEIAMKHRLGGGQYGDVYEAMWKRYNKIVAVKTLKEDTMALNDF 390
Query: 384 VECTMVEKRVLALPGKPPFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKE-PH 442
+E + K + K P L QL Y V E++ G+L+ +++ R + P
Sbjct: 391 LEEAAIMKEM-----KHPNLVQLLGVCTREPPFYIVTEFMPHGNLLDYLRSSTREENGPT 555
Query: 443 AVFY-AAEIAIGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTKTF 501
A+ Y A +IA G+ +L++K I+RDL N ++ +K+ADFG+ + D T
Sbjct: 556 ALMYMATQIASGMAYLETKNFIHRDLAARNCLVADSNMVKVADFGLARLMKDDTYTAHIG 735
Query: 502 CGTP-DYIAPEIIAYQPYGKSVDWWAFGVLLYEMLA-GQAPFEGEDEDELFQ 551
P + APE +A+ + D WAFGVLL+E+ G +P+ G + E++
Sbjct: 736 AKFPIKWTAPEGLAFNRFSTRSDIWAFGVLLWELATYGMSPYPGVELTEVYH 891
>09606
Length = 1300
Score = 96.7 bits (239), Expect = 3e-20, Method: Compositional matrix adjust.
Identities = 75/294 (25%), Positives = 125/294 (42%), Gaps = 30/294 (10%)
Frame = -3
Query: 338 KLTDFNFLMVLGKGSFGKVMLSERKGTDELYAVKILKKDVVIQDDDVECTMVEKRVLALP 397
++ +F LGKG + RKGT A+ ++K + +V T+ ++ P
Sbjct: 1121 RMENFVLYEELGKGEHSIIYKGRRKGTINFVAIHCIEK---CKRPEVTNTVRMTHDISHP 951
Query: 398 GKPPFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFL 457
+ Q H ++T + L+ V+E GG L + Q E + + GL ++
Sbjct: 950 N----VVQFHEWYETSNHLWLVVELCTGGSLADILAQDHHLPETSIRDFGIHLVTGLHYI 783
Query: 458 QSKGIIYRDLKLDNVMLDSEGHIKIADFGMCK---ENI-------------WDGVTTKTF 501
S GI++ DL+ V+LD+ G +K ADFG+ K EN+ W+ + +
Sbjct: 782 HSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQWNIQSAEEM 603
Query: 502 ------CGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIME 555
G+P Y+APE+ D WA G + YEM +G PF GE D ++
Sbjct: 602 MKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSGHPPFLGETYDITKDKVLN 423
Query: 556 HNVAYPKSM--------SKEAVAICKGLMTKHPGKRLGCGPEGERDIKEHAFFR 601
PK S E + + + L+ K +RL + +HAF++
Sbjct: 422 KEFPLPKVKGSRLSAKPSPEFLNLLESLLQKDSTRRLSWA-----SLVKHAFWQ 276
>13066
Length = 551
Score = 92.4 bits (228), Expect = 5e-19, Method: Compositional matrix adjust.
Identities = 46/132 (34%), Positives = 74/132 (56%), Gaps = 4/132 (3%)
Frame = +3
Query: 401 PFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSK 460
P++ Q+HS Q + + M + GDL+ +IQ+VG KE A + ++ L +L S
Sbjct: 156 PYIIQIHSILQRXPKNFIFMRFAERGDLLTYIQEVGFVKEKQAKIWFYQMTTALNYLHSY 335
Query: 461 GIIYRDLKLDNVMLDSEGHIKIADFGM---CKENIWDGVTTKTFCGTPDYIAPEIIAYQP 517
+ +RDLK +N++L S ++K+ADFG C + ++T+CG+ Y APEI+ P
Sbjct: 336 DVAHRDLKCENILLSSHFNVKLADFGFACACITESGEKYMSRTYCGSAAYAAPEIVYGAP 515
Query: 518 YG-KSVDWWAFG 528
Y K D W+ G
Sbjct: 516 YAPKVADAWSLG 551
>15910
Length = 1361
Score = 92.4 bits (228), Expect = 6e-19, Method: Compositional matrix adjust.
Identities = 53/165 (32%), Positives = 91/165 (55%), Gaps = 7/165 (4%)
Frame = +2
Query: 427 DLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSKGIIYRDLKLDNVM---LDSEGHIKIA 483
+L I G++ E A ++I G+ ++ + G+++RDLK +N++ + + +K+A
Sbjct: 422 ELFDRIVTRGQYTEKDAARAISDILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLA 601
Query: 484 DFGMCKENIWDGVTTKTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEG 543
DFG+ + I V T CGTP Y APE++ Y SVD W+ GV+ Y +L G PF
Sbjct: 602 DFGLSR-IIEPEVQMSTVCGTPGYCAPEVLKGDKYTPSVDMWSVGVIAYILLCGYEPFFA 778
Query: 544 EDEDELFQSIM----EHNVAYPKSMSKEAVAICKGLMTKHPGKRL 584
E+E E+++ I+ + + Y +S+ A + + L+ P KRL
Sbjct: 779 ENEFEMYRKIIKGEYKFDEEYWSEISENAKDVVRKLLVIDPKKRL 913
>18921
Length = 697
Score = 90.9 bits (224), Expect = 1e-18, Method: Compositional matrix adjust.
Identities = 60/202 (29%), Positives = 101/202 (50%), Gaps = 3/202 (1%)
Frame = +2
Query: 342 FNFLMVLGKGSFGKVMLSERKGTDELYAVKILKKDVVIQDDDVECTMVEKRVLALPGKPP 401
F+ L LG+GS+G V S K T ++ A+K + D +Q+ E +++++
Sbjct: 35 FDILGKLGEGSYGSVFKSLHKETGQVLAIKQVPVDTDLQEIIKEISIMQQ------CDSK 196
Query: 402 FLTQLHSCFQTMDRLYFVMEYVNGG---DLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQ 458
++ + + + L+ VMEY G D+M + +E + Y GL +L
Sbjct: 197 YIVKYYGSYFKNTDLWIVMEYCGAGSVSDIMRLRNKTLVEREIATILYYT--LKGLXYLH 370
Query: 459 SKGIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTKTFCGTPDYIAPEIIAYQPY 518
S+ I+RD+K N++L++EGH K+ADFG+ + T GTP ++APE+I Y
Sbjct: 371 SRRKIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTPYWMAPEVIQEIGY 550
Query: 519 GKSVDWWAFGVLLYEMLAGQAP 540
D W+ G+ EM G+ P
Sbjct: 551 DCVADIWSLGITALEMAEGKPP 616
>14420
Length = 528
Score = 90.9 bits (224), Expect = 2e-18, Method: Compositional matrix adjust.
Identities = 45/145 (31%), Positives = 75/145 (51%)
Frame = +2
Query: 401 PFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSK 460
P + + + L+ VME++ GG L + + E E L FL
Sbjct: 80 PNIVNYLDSYLVGEELWVVMEFLAGGSLTDVVTETC-MDEGQIAAVCRECLQALEFLHEN 256
Query: 461 GIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTKTFCGTPDYIAPEIIAYQPYGK 520
+I+RD+K DN++L +G +K+ DFG C + + T GTP ++APE++ + YG
Sbjct: 257 QVIHRDIKSDNILLGMDGSVKLTDFGFCAQLSPEQSKRSTMVGTPYWMAPEVVTRKQYGP 436
Query: 521 SVDWWAFGVLLYEMLAGQAPFEGED 545
+VD W+ GV+ EM+ G+ P+ E+
Sbjct: 437 TVDIWSLGVMCIEMIEGEPPYLNEN 511
>00300
Length = 2318
Score = 89.0 bits (219), Expect = 6e-18, Method: Compositional matrix adjust.
Identities = 67/249 (26%), Positives = 113/249 (45%), Gaps = 13/249 (5%)
Frame = -1
Query: 348 LGKGSFGKVMLSERKGTDELYAVKILKKDVVIQDDDVECT--MVEKRVLALPGKPPFLTQ 405
+G+G FGKV + T EL A+K +K Q +D++ M ++ + + L +
Sbjct: 1634 IGEGQFGKVYTAVNMSTGELMALKEMK----FQPNDLQQLREMCDEIKIFEGIQHENLVK 1467
Query: 406 LHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVF--YAAEIAIGLFFLQSKGII 463
+ D + MEY + G I++ + P + Y EI + + L I+
Sbjct: 1466 YYGVEVHKDEMLMFMEYCDTGT----IEEAAKMGLPEYLIRRYTREIVLAVNHLHENSIV 1299
Query: 464 YRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTT----KTFCGTPDYIAPEIIAYQP-- 517
+RD+K N+ L S GH+K+ DFG C + T GT Y+APE+
Sbjct: 1298 HRDIKGANIFLTSNGHVKLGDFG-CSVKLKSHTTMPGEFHNLVGTTAYMAPEVFTQNDQG 1122
Query: 518 -YGKSVDWWAFGVLLYEMLAGQAPFEGEDEDE--LFQSIMEHNVAYPKSMSKEAVAICKG 574
YG++ D W+ G ++ EM G+ P+ D + +++ + H A P S+S E
Sbjct: 1121 GYGRAADIWSLGCVVIEMATGKRPWHDLDNNYQIMYKVGIGHKPAVPDSLSVEGKHFLDL 942
Query: 575 LMTKHPGKR 583
+M P +R
Sbjct: 941 IMCHDPAQR 915
>21808
Length = 1011
Score = 84.3 bits (207), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 56/196 (28%), Positives = 94/196 (47%), Gaps = 3/196 (1%)
Frame = +1
Query: 369 AVKILKKDVVIQDDDVECTMVEKRVLALPGKPPFLTQLHSCFQTMDRLYFVMEYVNGGDL 428
A+K LK + D + + K++ + P L QL++ D ++ + E + G L
Sbjct: 31 AIKTLKSGTMDPKDFLAEAQIMKKL-----RHPKLIQLYAVCTQDDPIFIITELMKNGSL 195
Query: 429 MYHIQQVGR-FKEPHAVFYAAEIAIGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGM 487
+ +Q GR K P + A+IA G+ +L+S+ I+RDL N+++ +KIADFG+
Sbjct: 196 LEFLQGKGRVLKLPALIDIGAQIACGMAYLESQNYIHRDLAARNILVSDNNTVKIADFGL 375
Query: 488 CKENIWDGVTTKTFCGTP-DYIAPEIIAYQPYGKSVDWWAFGVLLYEMLA-GQAPFEGED 545
+ D + P + APE Y + D W+FG+LL E + G+ P+ G
Sbjct: 376 ARVIKEDEYEARVGARFPIKWTAPEAANYNRFTIKSDVWSFGILLTETVTYGRVPYPGMT 555
Query: 546 EDELFQSIMEHNVAYP 561
E+ + EH P
Sbjct: 556 NAEVLHQV-EHGYRMP 600
>01707
Length = 757
Score = 82.8 bits (203), Expect = 4e-16, Method: Compositional matrix adjust.
Identities = 65/207 (31%), Positives = 102/207 (49%), Gaps = 5/207 (2%)
Frame = +1
Query: 348 LGKGSFGKVMLSERKGTDELYAVKILKKDVVIQDDDV--ECTMVEKRVLALPGKPPFLTQ 405
+G+GS+G V K T +L A+K K V +DD + + M E R+L K P L +
Sbjct: 88 IGEGSYGVVFKCRNKETSQLVAIK---KFVESEDDPLIKKIAMREIRMLK-QLKHPNLVR 255
Query: 406 LHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGR-FKEPHAVFYAAEIAIGLFFLQSKGIIY 464
L F+ RL+ V +YV+ L+ + + R EP + + + F I+
Sbjct: 256 LIEVFRRKKRLHLVFDYVDH-TLLNELDRYPRGLPEPMVKRIIYQTLLAVNFCHQYNTIH 432
Query: 465 RDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTKTFCGTPDYIAPE-IIAYQPYGKSVD 523
RD+K +N+++ +G +K+ DFG + G + T Y APE ++ YG VD
Sbjct: 433 RDVKPENILITRQGQVKLCDFGFARILTGPGDEYTDYVATRWYRAPELLVGDTQYGPPVD 612
Query: 524 WWAFGVLLYEMLAGQAPFEGE-DEDEL 549
WA G + E+L GQA + G D D+L
Sbjct: 613 VWAIGCVFAELLTGQALWPGRSDVDQL 693
>01392
Length = 1806
Score = 79.7 bits (195), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 61/180 (33%), Positives = 84/180 (46%), Gaps = 32/180 (17%)
Frame = -1
Query: 436 GRFKEPHAVFYAAEIAIGLFFLQSKGIIYRDLKLDNVM---LDSEGHIKIADFGMCKENI 492
G E A IA L FL SKGI +RDLK +N++ LD +KI DF +
Sbjct: 1806 GHLCEREASLVVRHIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGIS 1627
Query: 493 WDGVTTKTF-----CGTPDYIAPEIIAYQ-----PYGKSVDWWAFGVLLYEMLAGQAPFE 542
DG TKT G+ +Y+APE++ Y K D W+ G++LY ML G PF
Sbjct: 1626 CDGDGTKTPELLTPVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILYIMLCGYPPFY 1447
Query: 543 ---GED------------EDELFQSIMEHNVAYPK----SMSKEAVAICKGLMTKHPGKR 583
GED +D LF SI + + +P S+S A + + L+ + P KR
Sbjct: 1446 GQCGEDCGWNRGEACHDCQDMLFNSIQDGHYKFPSQEWTSISSSAKDLIRHLLVREPRKR 1267
>21079
Length = 878
Score = 76.6 bits (187), Expect = 3e-14, Method: Compositional matrix adjust.
Identities = 45/143 (31%), Positives = 76/143 (53%), Gaps = 3/143 (2%)
Frame = +1
Query: 401 PFLTQLHSCFQTMDRLYFVMEYVNGGDLMYH-IQQVGRFKEPHAVFYAAEIAIGLFFLQS 459
P L L F+ + VME+V G+L I+ E V + +I G+ ++ +
Sbjct: 4 PKLLMLWDAFEAPRTMVLVMEFVGAGELFERVIRDDFVLTERDCVHFVRQICSGVGYMHT 183
Query: 460 KGIIYRDLKLDNVML--DSEGHIKIADFGMCKENIWDGVTTKTFCGTPDYIAPEIIAYQP 517
+ I++ DLK +NV+ D+ IKI DFG+ + G + + GTP++IAPE++ Y
Sbjct: 184 QSILHLDLKPENVLCVSDNSNQIKIIDFGLAR-FYKPGDSLQVLFGTPEFIAPEVVNYDE 360
Query: 518 YGKSVDWWAFGVLLYEMLAGQAP 540
+ D W+ GV+ Y +L+G +P
Sbjct: 361 INFTTDMWSIGVICYILLSGLSP 429
>13592
Length = 980
Score = 75.9 bits (185), Expect = 5e-14, Method: Compositional matrix adjust.
Identities = 66/249 (26%), Positives = 113/249 (45%), Gaps = 12/249 (4%)
Frame = +2
Query: 348 LGKGSFGKVMLSERKGTDELYAVKILKKDVVIQDDDVECTM-VEKRVLALPG-KPPFLTQ 405
+G+G FGKV + T EL A+K ++ IQ + V + + L G K L +
Sbjct: 8 IGQGRFGKVYTAVNNNTGELMAMK----EIAIQPGETRALKNVAEELKILEGIKHKNLVR 175
Query: 406 LHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSKGIIYR 465
+ + L ME + G L ++ G E + + A++ G+ L GI++R
Sbjct: 176 YYGIEVHREELLIFMELCSEGTLESLVELTGGLPEALSRRFTAQLLSGVAELHKHGIVHR 355
Query: 466 DLKLDNVML-DSEGHIKIADFGMCKENIWDGVTT----KTFCGTPDYIAPEIIA---YQP 517
D+K N+ L D +K+ DFG + I T + + GT Y+APE+
Sbjct: 356 DIKTANIFLVDGSNSLKLGDFGSAVK-IQAHTTVPGELQGYVGTQAYMAPEVFTKTNSDG 532
Query: 518 YGKSVDWWAFGVLLYEMLAGQAPFEGEDED--ELFQSIMEHNVAYPKSMSKEAVAICKGL 575
+G+ D W+ G ++ EM +G+ P+ D + +F+ M P+S+S+E
Sbjct: 533 HGRLADIWSVGCVVVEMASGKRPWAQFDSNFQIMFKVGMGEKPQAPESLSQEGHDFIDHC 712
Query: 576 MTKHPGKRL 584
+ P +RL
Sbjct: 713 LQHDPKQRL 739
>16549
Length = 607
Score = 72.8 bits (177), Expect = 5e-13, Method: Composition-based stats.
Identities = 32/89 (35%), Positives = 59/89 (66%), Gaps = 2/89 (2%)
Frame = +2
Query: 191 LSDPYVKLKLIPDPKSESKQKTKTIKCSLNPEWNETFRFQLKESD-KDRRLSVEIWDWDL 249
L PYVK L+PDP+ ++K+KTK +K S++P +NE ++++KE++ + R L V +WD D+
Sbjct: 56 LPSPYVKTYLLPDPEKQTKRKTKIVKHSVHPTFNEVLQYRMKETETRHRTLQVTVWDHDM 235
Query: 250 TSRNDFMGSLSFGISELQKA-SVDGWFKL 277
N+F+G++ + +L+ + W+ L
Sbjct: 236 LKENNFLGAVYLRLRDLELSDDTAKWYTL 322
>01060
Length = 1800
Score = 72.4 bits (176), Expect = 6e-13, Method: Compositional matrix adjust.
Identities = 61/221 (27%), Positives = 101/221 (45%), Gaps = 8/221 (3%)
Frame = +1
Query: 339 LTDFNFLMVLGKGSFGKVMLSERKGTDELYAVKILKKDVVIQDDDVECTMVEKRVLALPG 398
LTDF +G+G++G V + T A+K K + +D V + + + +
Sbjct: 79 LTDFQ---KIGEGTYGVVYKCRHRATGRKLAMK--KIRLRGSEDGVPSSAIREIAMLREL 243
Query: 399 KPPFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAV------FYAAEIAI 452
+ + L +RL+ V E+++ MY + +F E + Y +I
Sbjct: 244 RHTNIVCLEDVIMEDERLFLVFEFLSMDLKMY----IDKFPEGVVLDRRLVKSYVFQIVT 411
Query: 453 GLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTKTFCGTPDYIAPEI 512
G+ F + I++RDLK N++++ G IKIADFGM + T Y APEI
Sbjct: 412 GIXFCHQRRIVHRDLKPQNLLINHTGAIKIADFGMARTFALPVRAYTHEVVTLWYRAPEI 591
Query: 513 I-AYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDE-DELFQ 551
+ Y VD W+ G + +ML F+G+ E D+LF+
Sbjct: 592 LMGASKYSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFK 714
>14116
Length = 1017
Score = 71.6 bits (174), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 63/225 (28%), Positives = 106/225 (47%), Gaps = 21/225 (9%)
Frame = -1
Query: 333 NRDRMKLTDFNFLMV----------LGKGSFGKV-----MLSERKGTDELYAVKILKKDV 377
+ D MKL + L++ +GKG+FG V L E+KG D L AVK L +
Sbjct: 687 DEDMMKLIENESLLIDREFLTMGEEIGKGNFGCVKRGFLTLPEQKG-DILVAVKTLHNNN 511
Query: 378 VIQDDDVECTMVEKRVLALPGKPPFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHI---QQ 434
++ +++ + E ++ LT + C D V+ ++ GDL+ +I Q
Sbjct: 510 P-REIELQSFLQEALIMKDFHHSNVLTLIGICLNLDDMPLVVLPFMKHGDLLTYIRDDQH 334
Query: 435 VGRFKEPHAVFYAAEIAIGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCK---EN 491
K+ + Y +IA G+ +L ++RDL N MLD + H+K+ADFG+ + E
Sbjct: 333 QPTIKD--LIMYGVDIARGMDYLAGLKFVHRDLAARNCMLDEDFHVKVADFGLARDIYEK 160
Query: 492 IWDGVTTKTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLA 536
+ K ++A E + Y D W++GV+L+E+L
Sbjct: 159 EYYSSENKKAKLPVKWMALESLEKGNYDSKTDVWSYGVVLWELLT 25
>13212
Length = 1067
Score = 70.5 bits (171), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 36/106 (33%), Positives = 55/106 (51%), Gaps = 5/106 (4%)
Frame = -1
Query: 440 EPHAVFYAAEIAIGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTK 499
E + E+ + L FL +I+RD+K NV+L +G +K+ADFG+ +N
Sbjct: 983 EAQICYVCHEMCMALDFLHRHHVIHRDIKAGNVLLTIDGEVKLADFGVSAKNTQTQQKRD 804
Query: 500 TFCGTPDYIAPEIIAYQ-----PYGKSVDWWAFGVLLYEMLAGQAP 540
TF GTP ++APE++ + PY D W+ GV L E + P
Sbjct: 803 TFIGTPYWMAPEVVLCETLKDTPYDFKADIWSLGVTLIEFAQIEPP 666
>00392
Length = 668
Score = 68.9 bits (167), Expect = 6e-12, Method: Compositional matrix adjust.
Identities = 44/162 (27%), Positives = 90/162 (55%), Gaps = 7/162 (4%)
Frame = +3
Query: 416 LYFVMEYVNGGDLMYHIQQVGRFKEPHAVF---YAAEIAIGLFFLQSKG--IIYRDLKLD 470
+ V E + G L +++ RFK+P+ + ++ GL+FL ++ +I+RDLK D
Sbjct: 171 IILVTELMTSGTLKTYLK---RFKKPNVKILKNWCRQVLKGLYFLHTRTPPVIHRDLKCD 341
Query: 471 NVMLDS-EGHIKIADFGMCKENIWDGVTTKTFCGTPDYIAPEIIAYQPYGKSVDWWAFGV 529
N+ + G +KI D G+ + + K+ GTP+++APE+ + Y ++VD +AFG+
Sbjct: 342 NIFITGPTGSVKIGDLGLA--TLKNQSFAKSVIGTPEFMAPEMYE-EHYDEAVDVYAFGM 512
Query: 530 LLYEMLAGQAPF-EGEDEDELFQSIMEHNVAYPKSMSKEAVA 570
+ EM + + P+ E + ++++ + + P+++ K A+
Sbjct: 513 CMLEMASSEYPYSECSNAAQIYKRVT--SGVLPEALDKVAIT 632
>14126
Length = 1265
Score = 68.6 bits (166), Expect = 7e-12, Method: Compositional matrix adjust.
Identities = 36/103 (34%), Positives = 58/103 (56%)
Frame = +3
Query: 453 GLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTKTFCGTPDYIAPEI 512
G+ FL S I++RDLK N+++ +G +K+ADFG+ + + T T T Y +PE+
Sbjct: 552 GVDFLHSNRIVHRDLKPQNLLISKDGRLKLADFGLARIYSFHMALT-TVVVTLWYRSPEV 728
Query: 513 IAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIME 555
+ YG SVD W+ G + E+ +A F+G E + + I E
Sbjct: 729 LMQAEYGTSVDIWSCGCIFAELFTRRALFKGSSEFDQLKKIFE 857
>04852
Length = 1462
Score = 67.8 bits (164), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 65/246 (26%), Positives = 110/246 (44%), Gaps = 31/246 (12%)
Frame = +1
Query: 369 AVKILKKDV--VIQDDDVECTMVEKRVLALPGKPPFLTQLHSCFQTMDRLYFVMEYVNGG 426
AVK+L+ V V + D V+ V K V + + L C Q L+ ++E+ G
Sbjct: 31 AVKMLRDIVTAVEEQDFVQELQVMKAVKKMGSHINIVNFLGCCTQG-GPLWVIVEFAKNG 207
Query: 427 DLMYHIQQV-------GRFKEP------------------HAVFYAAEIAIGLFFLQSKG 461
+L ++ G+F P + + YA +IA G+ FL S+
Sbjct: 208 NLRDFLESCRDGINGYGKFVSPQDPGWYTKTPGGHVIRRKNLLSYAFQIARGMEFLASRK 387
Query: 462 IIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTKTFCGTP-DYIAPEIIAYQPYGK 520
I+RDL NV++ E +KIADFG+ + D ++ P ++APE + Y
Sbjct: 388 CIHRDLAARNVLVTEEHVLKIADFGLSRTG--DYYKKRSGGRLPVKWMAPEALFDMRYTT 561
Query: 521 SVDWWAFGVLLYEMLA-GQAPFEGEDEDELFQSIME--HNVAYPKSMSKEAVAICKGLMT 577
D W+FGV+L+E+ + G P+ +EL+ +++ + + P+ S AI +
Sbjct: 562 KSDVWSFGVVLWEIFSLGGMPYASIPNEELYSKLLDDAYRMPRPELASGNLYAIMERCWL 741
Query: 578 KHPGKR 583
P R
Sbjct: 742 NRPSDR 759
>19094
Length = 898
Score = 67.8 bits (164), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 34/90 (37%), Positives = 50/90 (55%)
Frame = +1
Query: 453 GLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTKTFCGTPDYIAPEI 512
GL +L S+ I+RD+K N++L++EGH K+ADFG+ + T GTP ++APE+
Sbjct: 94 GL*YLHSRRKIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTPYWMAPEV 273
Query: 513 IAYQPYGKSVDWWAFGVLLYEMLAGQAPFE 542
I Y D W+ G+ EM G E
Sbjct: 274 IQEIGYDCVADIWSLGITALEMAEGNLHME 363
>32957
Length = 645
Score = 66.6 bits (161), Expect = 3e-11, Method: Composition-based stats.
Identities = 28/54 (51%), Positives = 37/54 (68%)
Frame = +3
Query: 485 FGMCKENIWDGVTTKTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQ 538
F +C E G T+TFCGT +Y+APE+ + YGK VDWW G+LL+E+LA Q
Sbjct: 3 FALCVEK--SGGRTRTFCGTREYMAPEVHERKEYGKEVDWWGLGILLHELLAAQ 158
>29581
Length = 1278
Score = 65.5 bits (158), Expect = 6e-11, Method: Compositional matrix adjust.
Identities = 52/222 (23%), Positives = 91/222 (40%), Gaps = 31/222 (13%)
Frame = -2
Query: 411 QTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSKGIIYRDLKLD 470
+++D L+ VMEY F E ++ GL +L II+RDLK+
Sbjct: 1139 KSLDSLFLVMEYCEQDLASLLDNMPAPFSESQVKCIVLQLLKGLRYLHEAFIIHRDLKVS 960
Query: 471 NVMLDSEGHIKIADFGMCKENIWDGVTTKTFCGTPDYIAPEII-AYQPYGKSVDWWAFGV 529
N+++ +G +KIADFG+ + T Y APE++ + + ++D W+ G
Sbjct: 959 NLLMTDKGCVKIADFGLARNYGKPQKPMTPKVVTLWYRAPELLFGSKTHSTAIDMWSAGC 780
Query: 530 LLYEMLAGQAPFEGEDEDELFQSIME-----HNVAYP----------------------- 561
+L E+L + G + + + IME ++ +P
Sbjct: 779 ILGELLGHKPLMPGRSDLQQIELIMELLGTPNDTIWPGFSQLPAFEQFTLKKQPYNNLRH 600
Query: 562 --KSMSKEAVAICKGLMTKHPGKRLGCGPEGERDIKEHAFFR 601
+S+ + + GL HP KR D EH++F+
Sbjct: 599 TFPWLSESGIRLLNGLFMYHPQKR-----ATAEDCLEHSYFK 489
>27546
Length = 426
Score = 65.1 bits (157), Expect = 8e-11, Method: Compositional matrix adjust.
Identities = 30/89 (33%), Positives = 50/89 (56%)
Frame = -1
Query: 401 PFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSK 460
P + Q+HS Q +++ M Y GD++ HI++ G E + ++A L +L S
Sbjct: 300 PNIIQIHSILQRGPKIFIFMRYAEKGDMLSHIKKTGPIDEAQTKVWFFQMAKALQYLHSH 121
Query: 461 GIIYRDLKLDNVMLDSEGHIKIADFGMCK 489
I +RDLK +N++L ++KIADFG +
Sbjct: 120 DIAHRDLKCENILLSKRLNVKIADFGFAR 34
>09007
Length = 1440
Score = 62.8 bits (151), Expect = 5e-10, Method: Compositional matrix adjust.
Identities = 63/283 (22%), Positives = 116/283 (40%), Gaps = 16/283 (5%)
Frame = -1
Query: 317 PEEKTTNTVSKFDNNGNRDRMKLTDFNFLM-VLGKGSFGKV---MLSERKGTDELYAVKI 372
PE + + VS ++ D L LG+G FG V + + G AVK
Sbjct: 951 PEHRMSRPVSAVVRPARGKQLISKDCVALSKSLGQGHFGTVRQAIWTAESGEKVQVAVKC 772
Query: 373 LKKDVVIQDDDVECTMVEKRVLALPGKPPFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHI 432
L KD + +D + + E ++ + + + V E L+ +
Sbjct: 771 LSKDKIHKDG--QEFLKETAIMQMLDHENIVRVYGVVMDNGADIMLVTELAPMRSLLECV 598
Query: 433 QQVGR---FKEPHAVFYAAEIAIGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGM-- 487
++V F P ++ ++ G+ +L+SK +++RDL N++L S+ +KI+D G+
Sbjct: 597 KEVSARVDFSVPRLCDFSQQVCDGMSYLESKRLVHRDLAARNILLFSKSKVKISDVGVSG 418
Query: 488 ---CKENIWDGVTTKTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLA-GQAPFEG 543
+ + T + APE + + D WAFGVLL+E G P+ G
Sbjct: 417 ALGAGKEYYQSQQTIHLQNAVAWCAPESFRNLCFSSASDVWAFGVLLWEFFTHGFQPWAG 238
Query: 544 EDEDELFQSI---MEHNVAYPKSMSKEAVAICKGLMTKHPGKR 583
+ ++ +++ + P KE A+ + P +R
Sbjct: 237 LNGQQIMEAVDAPQSQRLEQPDLCPKEYYAVMLKCWEQEPQRR 109
>28638
Length = 1458
Score = 51.2 bits (121), Expect(2) = 6e-10, Method: Compositional matrix adjust.
Identities = 32/103 (31%), Positives = 55/103 (53%), Gaps = 7/103 (6%)
Frame = -1
Query: 446 YAAEIAIGLFFLQSK--GIIYRDLKLDNVMLDS--EGHIKIADFGM-CK--ENIWDGVTT 498
+A ++ L FL + II+ DLK +N++L + IKI DFG C+ + I+ + +
Sbjct: 822 FAQQLCTALLFLATPEMNIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQS 643
Query: 499 KTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAPF 541
+ Y +PE++ PY ++D W+ G +L EM G+ P
Sbjct: 642 RF------YRSPEVLLGVPYDLAIDMWSLGCILVEMHTGEPPL 532
Score = 31.2 bits (69), Expect(2) = 6e-10, Method: Compositional matrix adjust.
Identities = 21/76 (27%), Positives = 36/76 (47%), Gaps = 1/76 (1%)
Frame = -3
Query: 347 VLGKGSFGKVMLSERKGTDELYAVKILK-KDVVIQDDDVECTMVEKRVLALPGKPPFLTQ 405
++GKGSFG+V+ + G E A+KI+K K + +E ++E ++ +
Sbjct: 1126 LIGKGSFGQVVKAYDHGDQEQVAIKIIKNKKPFLNQAQIEVKLLELMNRHDADNXYYIVR 947
Query: 406 LHSCFQTMDRLYFVME 421
L F + L V E
Sbjct: 946 LKRHFMFRNHLCLVFE 899
>38560
Length = 479
Score = 61.6 bits (148), Expect = 1e-09, Method: Composition-based stats.
Identities = 30/86 (34%), Positives = 46/86 (53%), Gaps = 1/86 (1%)
Frame = -3
Query: 500 TFCGTPDYIAPEIIAYQPY-GKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHNV 558
T CG+P Y APE+I+ Y G D W+ GVLLY +L G PF+ E L Q +
Sbjct: 408 TCCGSPAYAAPELISGLEYLGSEADIWSMGVLLYALLCGYLPFDDEKXSHL*QKNQKRKD 229
Query: 559 AYPKSMSKEAVAICKGLMTKHPGKRL 584
P+ +S++ + +G++ P R+
Sbjct: 228 EVPEWLSEDTTKLLEGMLQTDPSHRI 151
>04591
Length = 1117
Score = 60.5 bits (145), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 31/109 (28%), Positives = 58/109 (53%), Gaps = 1/109 (0%)
Frame = -2
Query: 448 AEIAIGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTKTFCGTPDY 507
+++ GLF++ +K I++RD+K N++L +G +K+ADFG+ + + T T Y
Sbjct: 876 SQLLNGLFYIHTKQILHRDIKAANILLTRDGVLKLADFGLSRPWVKSKRLTNRVV-TLWY 700
Query: 508 IAPE-IIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIME 555
PE ++ + YG +D W G ++ EM + + +G E I +
Sbjct: 699 RPPELLLGEREYGPEIDMWGVGCIMAEMWSRKPLMQGRSEQHQLSLITD 553
>21433
Length = 590
Score = 60.5 bits (145), Expect = 2e-09, Method: Composition-based stats.
Identities = 35/96 (36%), Positives = 56/96 (58%)
Frame = +2
Query: 446 YAAEIAIGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTKTFCGTP 505
Y +++ L + + +I+RD+K +N++L +G +KIADFG TT CGT
Sbjct: 182 YIYQLSSALEYCHYRKVIHRDIKPENLLLGLKGDLKIADFGWSVHAPSSRRTT--MCGTL 355
Query: 506 DYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAPF 541
DY+ PE++ + + ++VD W+ GVL YE L G P
Sbjct: 356 DYLPPEMVEGKTHDENVDLWSLGVLCYEFLVGTPPL 463
>26711
Length = 405
Score = 60.1 bits (144), Expect = 3e-09, Method: Composition-based stats.
Identities = 29/94 (30%), Positives = 55/94 (58%), Gaps = 2/94 (2%)
Frame = -2
Query: 457 LQSKGIIYRDLKLDNVML--DSEGHIKIADFGMCKENIWDGVTTKTFCGTPDYIAPEIIA 514
+ ++G+++ DLK N++L D +++ DFG+ ++ ++ T GTP + +PE +
Sbjct: 368 VHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARK-LYPPQETFLNHGTPGFTSPEALD 192
Query: 515 YQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDE 548
+P + D W GVL Y +L+GQ+PF+ + E
Sbjct: 191 VKPISTASDVWGVGVLAYILLSGQSPFQADSATE 90
>07940
Length = 1336
Score = 60.1 bits (144), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 38/110 (34%), Positives = 60/110 (54%), Gaps = 3/110 (2%)
Frame = -3
Query: 444 VFYAAEIAIGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTKTFCG 503
+ YA ++A G+ +L SK I+RDL NV++ E +KIADFG+ + KT G
Sbjct: 338 ISYAYQVARGMEYLASKQCIHRDLAARNVLVAEEYVLKIADFGLTRNLQQFDYYRKTTDG 159
Query: 504 T--PDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLA-GQAPFEGEDEDELF 550
++APE + + Y D W++GVLL+E+ G P+ ++LF
Sbjct: 158 RLPVKWMAPEALFDRKYTSKSDVWSYGVLLWEIFTLGGNPYPSVPVEDLF 9
Score = 37.0 bits (84), Expect = 0.027, Method: Compositional matrix adjust.
Identities = 33/119 (27%), Positives = 53/119 (44%), Gaps = 5/119 (4%)
Frame = -3
Query: 334 RDRMKLTDFNFLMVLGKGSFGKVMLSERKG-----TDELYAVKILKKDVVIQDDDVECTM 388
R+R+ L D LG+G+FG VM E G AVK+LK+D D ++ +
Sbjct: 845 RERLVLGD-----RLGEGAFGLVMKGEAMGIFKDNNSVTVAVKMLKEDAT--DREMMDLI 687
Query: 389 VEKRVLALPGKPPFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYA 447
E ++ + GK + L C LY ++E+ G+L ++ PH Y+
Sbjct: 686 REMEMMKVIGKHKNIINLLGCCTQRGALYVIVEFAPHGNLRDFLKS----HRPHGTSYS 522
>37602
Length = 804
Score = 59.7 bits (143), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 32/90 (35%), Positives = 47/90 (52%), Gaps = 2/90 (2%)
Frame = -1
Query: 414 DRLYFVMEYVNGGDL--MYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSKGIIYRDLKLDN 471
++L+ MEY GG + +YH+ G EP F E GL +L +G ++RD+K N
Sbjct: 300 EKLWIAMEYCGGGSMQDIYHV--TGPLTEPQIAFVCRETLKGLHYLHRRGKMHRDIKGAN 127
Query: 472 VMLDSEGHIKIADFGMCKENIWDGVTTKTF 501
++L EG +K+ADF N V K F
Sbjct: 126 ILLTEEGDVKLADFWRVSSNHSHNVQKKVF 37
>11185
Length = 473
Score = 59.7 bits (143), Expect = 4e-09, Method: Composition-based stats.
Identities = 34/114 (29%), Positives = 54/114 (47%), Gaps = 22/114 (19%)
Frame = +1
Query: 446 YAAEIAIGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCK---ENI---------- 492
+ + GL ++ S GI++ DL+ V+LD+ G +K ADFG+ K EN+
Sbjct: 16 FGIHLVTGLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEA 195
Query: 493 ---WDGVTTKTF------CGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAG 537
W+ + + G+P Y+APE+ D WA G + YEM +G
Sbjct: 196 GDQWNIQSAEEMMKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSG 357
>35187
Length = 593
Score = 58.5 bits (140), Expect = 8e-09, Method: Compositional matrix adjust.
Identities = 25/51 (49%), Positives = 32/51 (62%)
Frame = -3
Query: 36 NHKFTARFFKQPTFCSHCTDFIWGFGKQGFQCQVCCFVVHKRCHEFVTFSC 86
H FT + F +PT+C HCTD +WG G+ C+VC FVVH RC + V C
Sbjct: 318 GHFFTKKTFHKPTYCHHCTDILWGLIGVGYVCEVCNFVVHDRCMKTVVSPC 166
Score = 48.9 bits (115), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 24/61 (39%), Positives = 31/61 (50%)
Frame = -3
Query: 93 PASDDPRSKHKFKIHTYSSPTFCDHCGSLLYGLIHQGMKCDTCMMNVHKRCVMNVPSLCG 152
P D H F T+ PT+C HC +L+GLI G C+ C VH RC+ V S C
Sbjct: 342 PVPPDHGHGHFFTKKTFHKPTYCHHCTDILWGLIGVGYVCEVCNFVVHDRCMKTVVSPCS 163
Query: 153 T 153
+
Sbjct: 162 S 160
>12672
Length = 773
Score = 58.2 bits (139), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 37/118 (31%), Positives = 61/118 (51%), Gaps = 4/118 (3%)
Frame = +3
Query: 451 AIGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFG-MCKENIWDGVTTK---TFCGTPD 506
A G+ +L G ++RD+K N++LDSE K+ DF + +G T + GT
Sbjct: 21 ASGIQYLNDNGHVHRDIKTANILLDSEYTAKVGDFATVVSAPSGEGKTVQNASVVIGTAA 200
Query: 507 YIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHNVAYPKSM 564
Y+APE I + K +D ++FGV+L E++ G + E+ S + NV P+ +
Sbjct: 201 YLAPEAIHFDVSTK-LDSYSFGVVLLEVITGLVAQDYSREERTLSSHIMENVEEPEEI 371
>29179
Length = 1113
Score = 57.8 bits (138), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 44/123 (35%), Positives = 66/123 (53%), Gaps = 4/123 (3%)
Frame = -3
Query: 148 PSLCGTDHTERRGRIYIQAHIDRDVLIVLVR--DAKNLVPMDPNGLSDPYVKLKLIPDPK 205
P + G D+ + GRI D L + +R A +L D G SDPYVK+ L+PD K
Sbjct: 568 PIVEGVDY--KLGRIQFGLMYDFQNLTLTLRIIRAVDLPAKDVTGTSDPYVKILLLPDKK 395
Query: 206 SESKQKTKTIKCSLNPEWNETFRFQLKESDK--DRRLSVEIWDWDLTSRNDFMGSLSFGI 263
K TK K +LNP WNE F F+ +K ++ L +++ D+D SR+D +G +
Sbjct: 394 --HKLLTKVKKRNLNPHWNECFLFEGWPHNKLLEKTLYLQVIDYDRFSRDDPIGETYLPL 221
Query: 264 SEL 266
+E+
Sbjct: 220 NEI 212
Score = 28.9 bits (63), Expect = 6.6, Method: Compositional matrix adjust.
Identities = 18/37 (48%), Positives = 21/37 (56%)
Frame = -1
Query: 164 IQAHIDRDVLIVLVRDAKNLVPMDPNGLSDPYVKLKL 200
I +I R L V+V AK L D G SDPYVK+ L
Sbjct: 120 ISPNIGR--LTVIVMKAKELKAKDITGSSDPYVKIWL 16
>01756
Length = 1858
Score = 57.8 bits (138), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 52/230 (22%), Positives = 102/230 (44%), Gaps = 19/230 (8%)
Frame = -3
Query: 345 LMVLGKGSFGKVMLSERKGTDELYAVKILKKDVVIQDDDVE----CTMVEKRVLALPGKP 400
L +G+G+FG+V + K T ++ A+K V+ D++ E + E ++L L
Sbjct: 1727 LAKIGQGTFGEVFKARCKKTKQVVAMK-----KVLMDNEKEGFPITALREIKILQLLNHE 1563
Query: 401 PFLTQLHSC---------FQTMDRLYFVMEYV--NGGDLMYHIQQVGRFKEPHAVFYAAE 449
+ + C +++M Y V E+ + L+ ++ V F P +
Sbjct: 1562 NVVDLIEICSTKATSANRYKSM--FYLVFEFCEHDLAGLLSNMSVV--FNLPEIKEVMKQ 1395
Query: 450 IAIGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCKE---NIWDGVTTKTFCGTPD 506
+ GL+++ I++RD+K N+++ +G +K+ADFG+ + N+ T
Sbjct: 1394 LMNGLYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLW 1215
Query: 507 YIAPE-IIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIME 555
Y PE ++ + Y ++D W G ++ EM +G E I +
Sbjct: 1214 YRPPELLLGDRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQNQLTLITQ 1065
>17300
Length = 480
Score = 57.4 bits (137), Expect = 2e-08, Method: Composition-based stats.
Identities = 31/109 (28%), Positives = 62/109 (56%), Gaps = 5/109 (4%)
Frame = +1
Query: 450 IAIGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCKE---NIWDGVTTKTFCGTP- 505
I+ G+ L G ++RDL N++++ K+ADFG+ +E + +G T P
Sbjct: 1 ISSGMGXLADMGYVHRDLAARNILVNEILVCKVADFGLSREIESDTTEGAYTTKGGKIPV 180
Query: 506 DYIAPEIIAYQPYGKSVDWWAFGVLLYEMLA-GQAPFEGEDEDELFQSI 553
+ APE IAY+ + + D W+FGV+++E+++ G+ P+ ++ +++
Sbjct: 181 RWTAPEAIAYRKFTSASDVWSFGVVMWEVMSYGERPYWNWSNQDVIKAV 327
>01966
Length = 1735
Score = 48.5 bits (114), Expect(2) = 3e-08, Method: Compositional matrix adjust.
Identities = 33/106 (31%), Positives = 52/106 (49%), Gaps = 6/106 (5%)
Frame = -1
Query: 414 DRLYFVMEYVNGGDLMYHIQQVGRFKEPHAV------FYAAEIAIGLFFLQSKGIIYRDL 467
+RL+ V E+++ MY + +F E + Y +I G+ F + I++RDL
Sbjct: 1495 ERLFLVFEFLSMDLKMY----IDKFPEGVVLDRRLVKSYVFQIVTGINFCHQRRIVHRDL 1328
Query: 468 KLDNVMLDSEGHIKIADFGMCKENIWDGVTTKTFCGTPDYIAPEII 513
K N++++ G IKIADFGM + T Y APEI+
Sbjct: 1327 KPQNLLINHTGAIKIADFGMARTFALPVRAYTHEVVTLWYRAPEIL 1190
Score = 27.7 bits (60), Expect(2) = 3e-08, Method: Compositional matrix adjust.
Identities = 13/35 (37%), Positives = 20/35 (57%), Gaps = 1/35 (2%)
Frame = -3
Query: 518 YGKSVDWWAFGVLLYEMLAGQAPFEGEDE-DELFQ 551
Y VD W+ G + +ML F+G+ E D+LF+
Sbjct: 1175 YSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFK 1071
>19761
Length = 473
Score = 55.5 bits (132), Expect = 6e-08, Method: Compositional matrix adjust.
Identities = 35/150 (23%), Positives = 67/150 (44%), Gaps = 2/150 (1%)
Frame = -3
Query: 431 HIQQVGRFKEPHAVFYAAEIAIGLFFLQSKG--IIYRDLKLDNVMLDSEGHIKIADFGMC 488
H+ E V + + A L ++ + I++RDLK N+ + +G +++ D G+
Sbjct: 453 HLGFTAGLPERLIVCWLMQTASALNYMHTHTPVILHRDLKPQNIYVTEKGDVRLGDLGLA 274
Query: 489 KENIWDGVTTKTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDE 548
++ + GT Y++PEI++ QPY D W+ G + Y++ + E
Sbjct: 273 RKLTGPADFATSQVGTIMYLSPEILSQQPYNSKSDIWSLGCVFYDITGKKGSDEMGVMFL 94
Query: 549 LFQSIMEHNVAYPKSMSKEAVAICKGLMTK 578
L Q + + P S+E ++TK
Sbjct: 93 LVQVMGGRKLPLPDHYSQEFRDTISRMLTK 4
>07291
Length = 833
Score = 55.5 bits (132), Expect = 6e-08, Method: Compositional matrix adjust.
Identities = 35/143 (24%), Positives = 66/143 (46%), Gaps = 5/143 (3%)
Frame = +1
Query: 446 YAAEIAIGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTKTFCGTP 505
+ +IA G+ +LQ +++R+L N ++ +G ++++D+G+ T
Sbjct: 64 FGRQIADGMAYLQEVKVVHRNLAARNCIVTEDGRLQLSDYGVTGSLFPQSYYTADDSPAR 243
Query: 506 D---YIAPEIIAYQPYGKSVDWWAFGVLLYEMLA-GQAPFEGEDEDELFQSIME-HNVAY 560
D ++APE I + D WAFGV+L+E+L G P+ + L + E H +
Sbjct: 244 DLVKWMAPETIDNFHFSSKSDVWAFGVVLWELLTRGITPYPDVENSSLLPYLKEGHRMKK 423
Query: 561 PKSMSKEAVAICKGLMTKHPGKR 583
PK + + + P +R
Sbjct: 424 PKQSPEPVYEMMTACWNESPEQR 492
>17932
Length = 597
Score = 42.0 bits (97), Expect(2) = 6e-08, Method: Composition-based stats.
Identities = 37/120 (30%), Positives = 57/120 (47%), Gaps = 6/120 (5%)
Frame = -3
Query: 552 SIMEHNVAYPKSMSKEAVAICKGLMTKHPGK-RLGCGPEGERDIKEHAFFRYIDWEKLER 610
+I + V S+SKEA + L++ GK RLG PE +++H FF+ +DW +
Sbjct: 496 TIRQTQVPPHSSVSKEARDLISQLLSD--GKSRLGW-PE----LQQHPFFKTVDWANI-- 344
Query: 611 KEIQPPYKPKARDKRDTSNFDKEFTRQPVE-----LTPTDKLFIMNLDQNEFAGFSYTNP 665
+ PPY P DTS+FD+ +P P+ + F F GF+Y +P
Sbjct: 343 RNAMPPYVPSISSLDDTSHFDEVEKARPAPNIDSFHQPSSRDFTGR--HLPFVGFTYFHP 170
Score = 33.5 bits (75), Expect(2) = 6e-08, Method: Composition-based stats.
Identities = 12/22 (54%), Positives = 14/22 (63%)
Frame = -2
Query: 524 WWAFGVLLYEMLAGQAPFEGED 545
WW+ GV YEML G PF +D
Sbjct: 596 WWSLGVCAYEMLFGCTPFTDDD 531
>11780
Length = 1713
Score = 49.7 bits (117), Expect(2) = 7e-08, Method: Compositional matrix adjust.
Identities = 37/151 (24%), Positives = 74/151 (49%), Gaps = 2/151 (1%)
Frame = +3
Query: 341 DFNFLMVLGKGSFGKVMLSERKGTDELYAVKILKKDVVIQDDDVECTMVEKRVLALPGKP 400
D +GKG FG V +G + A+K LK D E + +++ + +
Sbjct: 600 DLEIGEAIGKGDFGDVYKGMYRG--QPVAIKQLK-----DKDRGEQSFLQEASVMTSLRH 758
Query: 401 PFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGR--FKEPHAVFYAAEIAIGLFFLQ 458
L +L + ++ V E++ G+L+ +++ GR + + +A + + +L+
Sbjct: 759 DNLVRLIGVV-LGETIFLVTEFMGKGNLVEYLRSRGRSVITKKDQINFATDTCAAMEYLE 935
Query: 459 SKGIIYRDLKLDNVMLDSEGHIKIADFGMCK 489
SK +++RDL NV++ +G K++DFG+ K
Sbjct: 936 SKRLVHRDLAARNVLVHDDGKAKVSDFGLAK 1028
Score = 25.4 bits (54), Expect(2) = 7e-08, Method: Compositional matrix adjust.
Identities = 15/63 (23%), Positives = 30/63 (47%), Gaps = 2/63 (3%)
Frame = +1
Query: 523 DWWAFGVLLYEMLA-GQAPFEGEDEDELFQSIME-HNVAYPKSMSKEAVAICKGLMTKHP 580
D W+FG+LL+E+ + G+ P+ ++ + + + P+ E +I K P
Sbjct: 1120 DMWSFGILLWEIYSFGRVPYPRIPLTDVVMHVERGYRMEAPEGCPPEIYSIMKQAWELDP 1299
Query: 581 GKR 583
+R
Sbjct: 1300 NER 1308
>17591
Length = 474
Score = 55.1 bits (131), Expect = 8e-08, Method: Composition-based stats.
Identities = 34/93 (36%), Positives = 50/93 (53%), Gaps = 9/93 (9%)
Frame = +3
Query: 582 KRLGCGPEGERDIKEHAFFRYIDWEKLERKEIQPPYKPKARDKRDTSNFDKEFTRQPV-- 639
+RLG + E +I+E AFF I+W+ L K++QPPY P + D +FD EF R+PV
Sbjct: 153 ERLGAKRDFE-EIQEKAFFADINWDDLYNKKVQPPYNPNVSGQLDLRHFDPEFVREPVPA 329
Query: 640 -----ELTPTDKLFIMNLDQNE--FAGFSYTNP 665
+ KL ++ + + F GFSY P
Sbjct: 330 SVGRSGGGSSSKLVSASVMEADAVFDGFSYVPP 428
>00715
Length = 1788
Score = 55.1 bits (131), Expect = 8e-08, Method: Compositional matrix adjust.
Identities = 44/157 (28%), Positives = 67/157 (42%), Gaps = 27/157 (17%)
Frame = +1
Query: 414 DRLYFVMEYVNGGDLMY----HIQQVGRFKEPHAVFYAAEIAIGLFFLQSKGIIYRDLKL 469
D + MEYV +L H Q + + A ++A GL +L S I++ DLK
Sbjct: 154 DGAWLAMEYVGPLNLQTILNDHQQDI---DSSMRLSLALQMARGLHYLHSINIVHLDLKP 324
Query: 470 DNVMLDSEGHIKIADFGMCKE----------------------NIWDGVTTKTFCGTPDY 507
N +L + ++IADFG C + G GT Y
Sbjct: 325 ANCLLTRDLKLRIADFGCCHQLTPTGLDMGEREGGMAGNELELTPVQGAWKNELAGTLAY 504
Query: 508 IAPEII-AYQPYGKSVDWWAFGVLLYEMLAGQAPFEG 543
APE++ QP +S D ++ G+ L++M Q P+EG
Sbjct: 505 RAPELLKGLQPSVRS-DVYSLGITLWQMCTRQGPYEG 612
>33586
Length = 551
Score = 47.0 bits (110), Expect(2) = 8e-08, Method: Composition-based stats.
Identities = 21/53 (39%), Positives = 31/53 (58%), Gaps = 1/53 (1%)
Frame = +2
Query: 399 KPP-FLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEI 450
+PP F+ LH FQT +LY ++E++ GGDL + + F E FY AE+
Sbjct: 392 QPPLFIVHLHYAFQTEGKLYLILEFLRGGDLFTRLSKEVMFTEEDVKFYLAEL 550
Score = 27.7 bits (60), Expect(2) = 8e-08, Method: Compositional matrix adjust.
Identities = 12/22 (54%), Positives = 15/22 (68%)
Frame = +1
Query: 340 TDFNFLMVLGKGSFGKVMLSER 361
+ F L VLG+GSFG+V S R
Sbjct: 214 SQFELLKVLGQGSFGRVFXSGR 279
>11353
Length = 454
Score = 54.7 bits (130), Expect = 1e-07, Method: Composition-based stats.
Identities = 21/50 (42%), Positives = 29/50 (58%)
Frame = +1
Query: 102 HKFKIHTYSSPTFCDHCGSLLYGLIHQGMKCDTCMMNVHKRCVMNVPSLC 151
H+F+ +TY++PT+CD C LL+G G C C N H +C VP C
Sbjct: 142 HRFEKYTYTTPTYCDFCQQLLWGFSKTGTHCVDCGYNCHDKCQPLVPKTC 291
Score = 48.9 bits (115), Expect = 7e-06, Method: Composition-based stats.
Identities = 17/50 (34%), Positives = 24/50 (48%)
Frame = +1
Query: 37 HKFTARFFKQPTFCSHCTDFIWGFGKQGFQCQVCCFVVHKRCHEFVTFSC 86
H+F + PT+C C +WGF K G C C + H +C V +C
Sbjct: 142 HRFEKYTYTTPTYCDFCQQLLWGFSKTGTHCVDCGYNCHDKCQPLVPKTC 291
>29590
Length = 320
Score = 54.7 bits (130), Expect = 1e-07, Method: Composition-based stats.
Identities = 22/49 (44%), Positives = 29/49 (59%)
Frame = +3
Query: 495 GVTTKTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEG 543
G + GTPDY+APE++ Y+P D W+ GVL Y ML +PF G
Sbjct: 36 GEDIRDIIGTPDYVAPEVLDYEPLSIQTDMWSLGVLSYVMLTACSPFVG 182
>31935
Length = 554
Score = 53.9 bits (128), Expect = 2e-07, Method: Composition-based stats.
Identities = 38/130 (29%), Positives = 63/130 (48%), Gaps = 6/130 (4%)
Frame = -3
Query: 154 DHTERRGRIYIQAHIDRDVLIVLVRDAKNLVPMDPNGLSDPYVKLKLIPDPKSESKQKTK 213
+H R ++ I R L V + N+ DP+ + DPYVKL L+P ESK+KT
Sbjct: 549 EHGLGRIQLTITYSAQRQKLDVTIHKIMNIPLRDPSSIPDPYVKLHLLPGRSKESKRKTS 370
Query: 214 TIKCSLNPEWNETFRFQLKESD-KDRRLSVEIWDWD--LTSRNDFMGSLSFGISELQ--- 267
IK + NP ++ +F + + S+ + L V + L+S + +G L + + +
Sbjct: 369 IIKDNCNPVYDASFEYLISISELRHTELEVTVCTQKGFLSSGSPIIGMLKIPLDDSEITT 190
Query: 268 KASVDGWFKL 277
A + WF L
Sbjct: 189 PAGLKSWFDL 160
>03508
Length = 1463
Score = 53.5 bits (127), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 37/126 (29%), Positives = 60/126 (47%), Gaps = 2/126 (1%)
Frame = +1
Query: 418 FVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSKGIIYRDLKLDNVMLDSE 477
+ E+VN D Q F + FY E+ L F S GI++RD+K NVM+D E
Sbjct: 811 LIFEHVNNTDFK---QLYQTFTDYDIRFYLYELMKALDFCHSMGIMHRDVKPHNVMIDHE 981
Query: 478 G-HIKIADFGMCKENIWDGVTTKTFCGTPDYIAPEIIA-YQPYGKSVDWWAFGVLLYEML 535
+++ D+G+ E G+ + + PE++ YQ Y S+D W+ G + M+
Sbjct: 982 NKKLRLIDWGLA-EFYHPGMEYNVRVASRYFKGPELLLDYQMYDYSLDMWSLGCMFASMI 1158
Query: 536 AGQAPF 541
+ P
Sbjct: 1159FRKEPL 1176
>12786
Length = 460
Score = 53.5 bits (127), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 36/120 (30%), Positives = 55/120 (45%), Gaps = 22/120 (18%)
Frame = -3
Query: 445 FYAAEIAIGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWD--GVTTKTFC 502
FY E+ + L ++G+I+ DLK N ML + G++K+ DFG+ D V +
Sbjct: 398 FYWREMLRAVKALHNEGVIHSDLKPANFMLVA-GNLKLIDFGIANTLQQDKTSVLKDSRV 222
Query: 503 GTPDYIAPEIIAYQ--------------------PYGKSVDWWAFGVLLYEMLAGQAPFE 542
GTP Y++PE I G D W+ G +LY M+ G+ PF+
Sbjct: 221 GTPSYMSPEAIMAACDDSADDSMEEDGHRTKPKYKVGVRSDVWSLGCILYNMVYGRTPFQ 42
>30339
Length = 384
Score = 52.8 bits (125), Expect = 5e-07, Method: Composition-based stats.
Identities = 24/35 (68%), Positives = 27/35 (77%)
Frame = -2
Query: 329 DNNGNRDRMKLTDFNFLMVLGKGSFGKVMLSERKG 363
D + DR L DFNF+ VLGKGSFGKVML+ERKG
Sbjct: 107 DRGRSSDRFHLHDFNFIKVLGKGSFGKVMLAERKG 3
>19361
Length = 685
Score = 51.6 bits (122), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 21/72 (29%), Positives = 36/72 (50%), Gaps = 9/72 (12%)
Frame = -1
Query: 89 ADKGPASDDPRSK---------HKFKIHTYSSPTFCDHCGSLLYGLIHQGMKCDTCMMNV 139
+ P D+P H FK+ ++ +C+ C + ++GLI QG+KC C +
Sbjct: 382 VNSTPEEDEPEQSIDWTQYEKPHVFKVQNFNGLNWCELCANFMWGLIAQGVKCQDCGVQT 203
Query: 140 HKRCVMNVPSLC 151
HK+C +P+ C
Sbjct: 202 HKKCSERMPNEC 167
Score = 45.8 bits (107), Expect = 5e-05, Method: Compositional matrix adjust.
Identities = 19/52 (36%), Positives = 26/52 (50%)
Frame = -1
Query: 35 KNHKFTARFFKQPTFCSHCTDFIWGFGKQGFQCQVCCFVVHKRCHEFVTFSC 86
K H F + F +C C +F+WG QG +CQ C HK+C E + C
Sbjct: 322 KPHVFKVQNFNGLNWCELCANFMWGLIAQGVKCQDCGVQTHKKCSERMPNEC 167
>17975
Length = 449
Score = 50.8 bits (120), Expect = 2e-06, Method: Composition-based stats.
Identities = 40/138 (28%), Positives = 71/138 (51%), Gaps = 4/138 (2%)
Frame = +3
Query: 353 FGKVMLSERKGTDELYAVKILKKDVVIQDDDVECTMV--EKRVLALPGKPPFLTQLHSCF 410
F V L+ T E AVK++ K + D+V + + E R + L + P + +L+
Sbjct: 6 FAVVKLARHVFTGEKVAVKVIDKTKL---DEVSRSHLFQEVRCMKLV-QHPNVVRLYEVI 173
Query: 411 QTMDRLYFVMEYVNGGDLM-YHIQQVGRFKEPHAVFYAAEIAIGLFFLQSKGIIYRDLKL 469
T +LY ++E +GGD+ Y ++ G +E A Y +I + + +++RDLK
Sbjct: 174 DTQTKLYLILELGDGGDMYDYIMRHSGGLEEKLAKRYFRQIVEAISYCHKLHVVHRDLKP 353
Query: 470 DNVM-LDSEGHIKIADFG 486
+NV+ + G +K+ DFG
Sbjct: 354 ENVVFFEKPGLVKLTDFG 407
>30040
Length = 652
Score = 50.1 bits (118), Expect = 3e-06, Method: Composition-based stats.
Identities = 28/91 (30%), Positives = 46/91 (50%), Gaps = 1/91 (1%)
Frame = -3
Query: 173 LIVLVRDAKNLVPMDPNGLSDPYVKLKLIPDPKSESKQKTKTIKCSLNPEWNETFRFQL- 231
L V++ AK+L + +DP+V++ L+ + K ++KT + S+NP WNE F +
Sbjct: 611 LTVVLMKAKDLKMSTSHPSADPFVRVSLLVEGKKVKRKKTSVRRASINPVWNEALAFNVP 432
Query: 232 KESDKDRRLSVEIWDWDLTSRNDFMGSLSFG 262
E L V + D DL D +G+ G
Sbjct: 431 AEVLPKVTLEVSVLDHDLIGHGDVLGTCVLG 339
>22804
Length = 967
Score = 49.7 bits (117), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 21/51 (41%), Positives = 29/51 (56%)
Frame = -3
Query: 102 HKFKIHTYSSPTFCDHCGSLLYGLIHQGMKCDTCMMNVHKRCVMNVPSLCG 152
H+F+ +TY++PT+CD C LL+G G C C N H +C VP C
Sbjct: 830 HRFEKYTYTTPTYCDFCQQLLWGFSKTGTHCVDCGYNCHDKCQPLVPKTCS 678
Score = 43.5 bits (101), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 17/50 (34%), Positives = 24/50 (48%)
Frame = -3
Query: 37 HKFTARFFKQPTFCSHCTDFIWGFGKQGFQCQVCCFVVHKRCHEFVTFSC 86
H+F + PT+C C +WGF K G C C + H +C V +C
Sbjct: 830 HRFEKYTYTTPTYCDFCQQLLWGFSKTGTHCVDCGYNCHDKCQPLVPKTC 681
>01718
Length = 959
Score = 48.5 bits (114), Expect = 8e-06, Method: Compositional matrix adjust.
Identities = 35/129 (27%), Positives = 67/129 (51%), Gaps = 7/129 (5%)
Frame = +3
Query: 415 RLYFVMEYVNGGDLMYHIQQVGR-FKEPHAVFYAAEIAIGLFFLQSKGIIYRDLKLDNVM 473
+L+ + EY+ G+L +++ + +A GL +L S I+RDL N++
Sbjct: 354 QLHALTEYIPSGNLEQLLEKKDEELPWTQRIQLTLGLARGLDYLHSTRFIHRDLTSKNIL 533
Query: 474 L---DSEG-HIKIADFGMCKENIWDGVTTKTF--CGTPDYIAPEIIAYQPYGKSVDWWAF 527
+ D+ G H IADFG+ + I D + + G+P ++APE++ Y + D ++
Sbjct: 534 IRREDNHGYHAVIADFGLATK-IPDPLDKEKLPTVGSPYWMAPEVLNGHFYNERADLFSV 710
Query: 528 GVLLYEMLA 536
G+++ E+ A
Sbjct: 711 GIIMCEITA 737
>26525
Length = 455
Score = 48.5 bits (114), Expect = 1e-05, Method: Composition-based stats.
Identities = 24/49 (48%), Positives = 36/49 (73%), Gaps = 1/49 (2%)
Frame = +1
Query: 182 NLVPMDPN-GLSDPYVKLKLIPDPKSESKQKTKTIKCSLNPEWNETFRF 229
+L P DP+ G DPYVKL+L+P+ K K KT+ ++ +LNP+++ETF F
Sbjct: 1 DLPPRDPSLGGCDPYVKLQLLPEKKH--KCKTRVVRKTLNPKYDETFTF 141
Score = 30.0 bits (66), Expect = 3.3, Method: Composition-based stats.
Identities = 12/19 (63%), Positives = 16/19 (84%)
Frame = +2
Query: 180 AKNLVPMDPNGLSDPYVKL 198
++NL MD +GLSDPYVK+
Sbjct: 398 SRNLPKMDISGLSDPYVKI 454
>20640
Length = 1492
Score = 47.0 bits (110), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 34/128 (26%), Positives = 58/128 (45%), Gaps = 4/128 (3%)
Frame = +1
Query: 460 KGIIYRDLKLDNVMLDSEGHIKIADFGMCKE-NIWDGVTTKTFCGTPDYIAP-EIIAYQP 517
+G ++RDL N ++ + +KI+DFG+ + + D P P E I Y
Sbjct: 1 RGYVHRDLATRNCLVGHDLVVKISDFGLARSVHSVDYYRGSEHDAIPIRWMPLEAILYNK 180
Query: 518 YGKSVDWWAFGVLLYEMLA-GQAPFEGEDEDELFQSIMEHNV-AYPKSMSKEAVAICKGL 575
+ D W+FGV+L+E+ A P+ G +E+ + + E V A P+ + K
Sbjct: 181 FSTQSDVWSFGVVLWEIFAFALQPYYGLTHEEVVRFVKEGKVLACPERTPPPMYELMKQC 360
Query: 576 MTKHPGKR 583
+ P R
Sbjct: 361 WHRRPATR 384
>19301
Length = 712
Score = 46.6 bits (109), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 27/70 (38%), Positives = 41/70 (58%), Gaps = 1/70 (1%)
Frame = +2
Query: 418 FVMEYVNGGDLMYHIQQVGRFKEPHAVF-YAAEIAIGLFFLQSKGIIYRDLKLDNVMLDS 476
+MEY G L Y + + G+ P V ++ +IA G+ +L S II+RDLK NV++
Sbjct: 500 IIMEYCPYGQL-YEVLRDGKEIPPALVLDWSKQIASGMNYLHSHKIIHRDLKSPNVLVAK 676
Query: 477 EGHIKIADFG 486
+KI+DFG
Sbjct: 677 NDVVKISDFG 706
>20152
Length = 445
Score = 46.2 bits (108), Expect = 4e-05, Method: Composition-based stats.
Identities = 22/75 (29%), Positives = 40/75 (53%), Gaps = 1/75 (1%)
Frame = +1
Query: 510 PEIIAYQPY-GKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHNVAYPKSMSKEA 568
PEI+ Y +VD W+ GV+LY ++ G+APF+ ++ E IM+ P +S +
Sbjct: 1 PEILLGDSYDAPAVDVWSLGVILYMLVVGEAPFQEANDSETLTMIMDCRYQIPPHISHKC 180
Query: 569 VAICKGLMTKHPGKR 583
+ + ++ + P R
Sbjct: 181 QDLIEKMLQREPVDR 225
>04138
Length = 800
Score = 46.2 bits (108), Expect = 4e-05, Method: Compositional matrix adjust.
Identities = 26/106 (24%), Positives = 50/106 (47%), Gaps = 4/106 (3%)
Frame = +1
Query: 454 LFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCKE---NIWDGVTTKTFCGTPDYIAP 510
L+++ I++RD+K N+++ +G +K+ADFG+ + N+ T Y P
Sbjct: 52 LYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRPP 231
Query: 511 E-IIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIME 555
E ++ + Y ++D W G ++ EM +G E I +
Sbjct: 232 ELLLGDRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQNQLTLITQ 369
>07833
Length = 1504
Score = 45.1 bits (105), Expect = 9e-05, Method: Compositional matrix adjust.
Identities = 51/199 (25%), Positives = 86/199 (43%), Gaps = 8/199 (4%)
Frame = -3
Query: 393 VLALPGKPPFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAI 452
VLA +PP L L S F LY + +G ++ Q RF A +IA
Sbjct: 1424 VLACCNQPPNLV-LISQFMPFGSLYNTLHGESG--IVVDQNQSLRF--------AMDIAR 1278
Query: 453 GLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWD---GVTTKTFCGTPDYIA 509
G+ FL S + + N +L S+ H+ I + + N+ D K +P ++A
Sbjct: 1277 GMEFLHSM-----EPTIPNFLLTSK-HVMIDEDLTARINMADYCFSFHEKGKVYSPAWMA 1116
Query: 510 PEIIAYQP---YGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHN--VAYPKSM 564
PE + +P ++ D W+F +L++E+ + PF E+ + ++ P +
Sbjct: 1115 PEALQRRPDDINTRAADMWSFAILMWELETREVPFAELSSMEVGMKVALEGLRISIPPGI 936
Query: 565 SKEAVAICKGLMTKHPGKR 583
S + K M + PGKR
Sbjct: 935 SLHMSRLIKICMNEEPGKR 879
>07591
Length = 796
Score = 45.1 bits (105), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 27/101 (26%), Positives = 50/101 (49%), Gaps = 3/101 (2%)
Frame = +2
Query: 174 IVLVRDAKNLVPMDPNGLSDPYVK-LKLIPDPKSESKQKTKTIKCSLNPEWN--ETFRFQ 230
+ + AK L D G SDPY++ L+ D + +T+ +K +LNP W E
Sbjct: 461 VAMTFHAKKLDKKDFLGKSDPYLEVLRATSDGSWQMVHRTEVVKNNLNPSWRPFELSMQT 640
Query: 231 LKESDKDRRLSVEIWDWDLTSRNDFMGSLSFGISELQKASV 271
L + + + +++DWD +D++G + + ++ KAS
Sbjct: 641 LCGGNHQQNIKFDVYDWDSDGSHDYIGGFTTTLQDMLKASA 763
>30743
Length = 569
Score = 44.7 bits (104), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 18/39 (46%), Positives = 22/39 (56%)
Frame = +2
Query: 106 IHTYSSPTFCDHCGSLLYGLIHQGMKCDTCMMNVHKRCV 144
+HT+ P CD CG LL G+ QG C M VHK C+
Sbjct: 338 MHTFEKPKECDVCGKLLRGIFFQGYLCQDNQMAVHKECI 454
Score = 28.9 bits (63), Expect = 6.4, Method: Compositional matrix adjust.
Identities = 13/35 (37%), Positives = 17/35 (48%)
Frame = +2
Query: 44 FKQPTFCSHCTDFIWGFGKQGFQCQVCCFVVHKRC 78
F++P C C + G QG+ CQ VHK C
Sbjct: 347 FEKPKECDVCGKLLRGIFFQGYLCQDNQMAVHKEC 451
>27274
Length = 396
Score = 44.3 bits (103), Expect = 2e-04, Method: Composition-based stats.
Identities = 27/94 (28%), Positives = 49/94 (52%), Gaps = 5/94 (5%)
Frame = -1
Query: 511 EIIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGE-DEDELFQSIMEHNVAYPKSMSKEAV 569
E++ Q +G +VD W+ G+LL+E+L+G PFE E ++ +++M Y + + +
Sbjct: 375 ELLRGQQHGPTVDMWSLGILLHELLSGHVPFEPERGSRQMARNMM---AVYAQIIRGSSR 205
Query: 570 AICKGLMTKHPG----KRLGCGPEGERDIKEHAF 599
+C GL G +RL + +R + AF
Sbjct: 204 DVCDGLALSTHGADFLRRLVQLEDTKRLTSQQAF 103
>16708
Length = 1397
Score = 43.5 bits (101), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 45/160 (28%), Positives = 67/160 (41%), Gaps = 14/160 (8%)
Frame = -1
Query: 344 FLMVLGKGSFGKVMLSERKGTDELYAVKILKKDVVIQD--DDVECT-----------MVE 390
L VLGKG FGKV + T E A LK ++ D+VE M
Sbjct: 1391 ILQVLGKGVFGKVYEARLLSTHEKAA---LKTSILCHHSLDEVEALGRIEGGFYLAQMFG 1221
Query: 391 KRVLALPGKPPFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVF-YAAE 449
V LP P LH F M L V + ++ R+ P V A +
Sbjct: 1220 AWVTCLP-FPKMNILLH--FYEMGPLCNVYAHYKNKEMPI------RWSNPAMVCCIAGQ 1068
Query: 450 IAIGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCK 489
L + G+++ D+K DNV++D+ G+ K+ D+G+ +
Sbjct: 1067 XVCALEHIHELGVVHMDVKADNVLVDAHGNCKLTDYGIAQ 948
>03942
Length = 912
Score = 40.8 bits (94), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 24/63 (38%), Positives = 33/63 (52%), Gaps = 3/63 (4%)
Frame = +2
Query: 549 LFQSIMEHNVAYPKSMSKEAVAICKGLMTKHPGKRLGCGPE--GERDIKEHAFF-RYIDW 605
L+ ++ + AY M ++ MTK+P KRLGC E+ I HAFF + IDW
Sbjct: 29 LYMQVLCNEYAYLVYMFSMSLFCIFQFMTKNPAKRLGCVTSQGAEKAIFIHAFFHQKIDW 208
Query: 606 EKL 608
E L
Sbjct: 209 EAL 217
>36305
Length = 586
Score = 40.8 bits (94), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 26/77 (33%), Positives = 39/77 (50%)
Frame = -1
Query: 190 GLSDPYVKLKLIPDPKSESKQKTKTIKCSLNPEWNETFRFQLKESDKDRRLSVEIWDWDL 249
G SDPY + + KTK I ++ P WNE F F + E D + L + I D D
Sbjct: 583 GKSDPYTVVTV-----GAQTFKTKVIDDTVEPRWNEVFEFVIDERDG-QILKLNISDKDP 422
Query: 250 TSRNDFMGSLSFGISEL 266
+++D +GS + IS +
Sbjct: 421 GNKDDPLGSTTMDISTI 371
Score = 31.6 bits (70), Expect = 1.1, Method: Composition-based stats.
Identities = 19/62 (30%), Positives = 33/62 (53%)
Frame = -3
Query: 168 IDRDVLIVLVRDAKNLVPMDPNGLSDPYVKLKLIPDPKSESKQKTKTIKCSLNPEWNETF 227
++ D + L RD K+L ++P+ PYV L+L +++Q++ + P W E F
Sbjct: 194 VNLDSALDLPRDKKSL--LEPS----PYVTLRL-----GQTEQESGIRNATTEPRWEENF 48
Query: 228 RF 229
RF
Sbjct: 47 RF 42
>18996
Length = 491
Score = 40.4 bits (93), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 24/83 (28%), Positives = 45/83 (54%), Gaps = 5/83 (6%)
Frame = +2
Query: 463 IYRDLKLDNVMLDSEGHIKIADFGMCK----ENIWDGVTTKTFCGTPDYIAPEIIAYQPY 518
I+RDL N+++D +KI+DFG+ + + + G++ + + +PE I +
Sbjct: 2 IHRDLAARNILVD-RSCVKISDFGLAQFANADGYYYGISQRDI--PIKWYSPEAIETCKF 172
Query: 519 GKSVDWWAFGVLLYEMLA-GQAP 540
D W++GV L+EM + G+ P
Sbjct: 173 SSYSDVWSYGVTLFEMFSRGEIP 241
>07836
Length = 1478
Score = 40.0 bits (92), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 36/138 (26%), Positives = 66/138 (47%), Gaps = 18/138 (13%)
Frame = -1
Query: 415 RLYFVMEYVNGGDLM-YHIQQVGRFKEPHAVFYAA-----EIAIGLFFLQSK-GIIYRDL 467
+L+ + +Y G L Y + +V E A+ ++A + I +F + K I +RD+
Sbjct: 1331 QLFLITDYHENGSLHDYLLSRVLDSSEMLALAHSAICGLAHLHIEIFGTRGKPAIAHRDI 1152
Query: 468 KLDNVMLDSEGHIKIADFGMCKENIWDG----VTTKTFCGTPDYIAPEIIA-------YQ 516
K N+++ G IAD G+ I + V GT Y+APE++ +
Sbjct: 1151 KSKNILVKKNGTCCIADLGLAVRYISESNEVDVAPNPRQGTKRYMAPEVLEMLLNVKNFD 972
Query: 517 PYGKSVDWWAFGVLLYEM 534
+ K D +AFG++++E+
Sbjct: 971 AF-KQADMYAFGLVMWEI 921
>02638
Length = 1490
Score = 38.1 bits (87), Expect = 0.011, Method: Compositional matrix adjust.
Identities = 14/43 (32%), Positives = 26/43 (60%)
Frame = +1
Query: 503 GTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGED 545
GT ++APE++ + YG++ D W+ G ++ EM + P+ D
Sbjct: 22 GTIAFMAPEVLRGESYGRACDVWSVGCVMIEMCTCRPPWNSHD 150
>12442
Length = 468
Score = 36.6 bits (83), Expect = 0.031, Method: Composition-based stats.
Identities = 20/37 (54%), Positives = 23/37 (62%), Gaps = 3/37 (8%)
Frame = +3
Query: 575 LMTKHPGKRLGC--GPEGERDIKEHAFF-RYIDWEKL 608
MTK+P KRLGC E+ I HAFF + IDWE L
Sbjct: 105 FMTKNPAKRLGCVTSQGAEKAIFIHAFFHQKIDWEAL 215
>14477
Length = 493
Score = 36.2 bits (82), Expect = 0.040, Method: Compositional matrix adjust.
Identities = 36/148 (24%), Positives = 68/148 (45%), Gaps = 6/148 (4%)
Frame = -1
Query: 348 LGKGSFGKVMLSERKGTDEL------YAVKILKKDVVIQDDDVECTMVEKRVLALPGKPP 401
LG G+FG VM KG L A+K+LK + D V+ ++++ +
Sbjct: 466 LGAGNFGSVM----KGVCRLDDREIPVAIKVLKNADL--DPSVQSELIKEAEVMKKMDHM 305
Query: 402 FLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSKG 461
+ +L + + + V+E G L + + + + +++ G+ +L++
Sbjct: 304 HIVRLIGLCEG-ETMMLVLELAKLGPLNKFLPKNKHLPLWNILELMWQVSQGMEYLEANK 128
Query: 462 IIYRDLKLDNVMLDSEGHIKIADFGMCK 489
++RDL N++L E KI+DFGM K
Sbjct: 127 FVHRDLAARNILLCDEHFAKISDFGMSK 44
>11404
Length = 563
Score = 36.2 bits (82), Expect = 0.041, Method: Compositional matrix adjust.
Identities = 33/134 (24%), Positives = 62/134 (46%), Gaps = 6/134 (4%)
Frame = +1
Query: 347 VLGKGSFGKVMLSERKGTDELYAVKILK-KDVVIQDDDVECTMVEKRVLALPGKPPFLTQ 405
++GKGSFG+V+ + +E A+KI+K K + +E ++E ++ +
Sbjct: 160 LIGKGSFGQVVKAYDHTDNEQVAIKIIKNKKPFLNQAQIEVKLLEMMNRHDTDNKYYIVR 339
Query: 406 LHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVF---YAAEIAIGLFFLQS--K 460
L F L V E ++ +Y + + F+ +A ++ L FL +
Sbjct: 340 LKRHFMFRSHLCLVFELLSYN--LYDLLRNTNFRGVSLNLTRKFAQQLCTALLFLATPEM 513
Query: 461 GIIYRDLKLDNVML 474
II+ DLK +N++L
Sbjct: 514 SIIHCDLKPENILL 555
>18401
Length = 463
Score = 35.8 bits (81), Expect = 0.065, Method: Compositional matrix adjust.
Identities = 20/70 (28%), Positives = 34/70 (48%), Gaps = 1/70 (1%)
Frame = -3
Query: 500 TFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHNV- 558
T T Y APE+I + D W+ G +++E+ G F+ D E ++ME +
Sbjct: 455 TIVSTRHYRAPEVILELGWSHPCDVWSVGCIMFELYTGYTLFQTHDNKEHL-AMMERILG 279
Query: 559 AYPKSMSKEA 568
+ P M+K+
Sbjct: 278 SLPYRMAKKT 249
>31120
Length = 439
Score = 34.3 bits (77), Expect = 0.15, Method: Composition-based stats.
Identities = 15/42 (35%), Positives = 26/42 (61%), Gaps = 1/42 (2%)
Frame = +1
Query: 511 EIIAYQPYG-KSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQ 551
E++ PY K D W+ GV+L+ ML G+ PF+ + ++L +
Sbjct: 1 EVVCGVPYDPKMADAWSLGVILFIMLNGKMPFDDSNLNKLLE 126
>22005
Length = 873
Score = 34.3 bits (77), Expect = 0.15, Method: Compositional matrix adjust.
Identities = 26/106 (24%), Positives = 46/106 (43%), Gaps = 6/106 (5%)
Frame = +1
Query: 436 GRFKEPHAVFYAAEIAIGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDG 495
G ++ + +I+ G+ +L K ++RDL V I+DFG+ +
Sbjct: 427 GMLXTKDQLYISQQISAGMAYLAQKDYVHRDLATRTVXS-RTT*S*ISDFGLARSV---- 591
Query: 496 VTTKTFCGTPDYIAP------EIIAYQPYGKSVDWWAFGVLLYEML 535
+ + G+ P E I Y + D W+FGV+L+E+L
Sbjct: 592 HSVDYYRGSEQDAIPIRWMPLEAILYSKFSTQSDVWSFGVVLWEIL 729
>17253
Length = 483
Score = 33.5 bits (75), Expect = 0.27, Method: Composition-based stats.
Identities = 24/109 (22%), Positives = 49/109 (44%), Gaps = 15/109 (13%)
Frame = -1
Query: 396 LPGKPPFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVF---------- 445
LP P ++ + C + D +ME+ GDL+ ++ + + VF
Sbjct: 378 LPRHPNVVSFMGCCTMS-DPALILMEFCCHGDLLSFLR---KRRPDRTVFLTSTANDLTA 211
Query: 446 -----YAAEIAIGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCK 489
+A +A G+ + + I++RD+ NV++ K++DFG+ +
Sbjct: 210 RDFFSFALHVARGMAHVANNKIVHRDVAARNVLISERNVCKVSDFGLSR 64
>13896
Length = 827
Score = 33.1 bits (74), Expect = 0.37, Method: Compositional matrix adjust.
Identities = 28/103 (27%), Positives = 49/103 (47%), Gaps = 2/103 (1%)
Frame = +2
Query: 177 VRDAKNLVPMDPNGLSDPYVKLKLIPDPKSESKQKTKTIKCSLNPEWNETFRFQLKESDK 236
V A+NL+ +G +D YV ++L + K +T TI+ + NPEW E +
Sbjct: 170 VLRARNLISKGKSGNNDVYVTIQL-----GKEKYQTSTIRNAHNPEWFEECDLPIPHLHS 334
Query: 237 DRRLSVEIWDWDLTSRNDFMGSLSFGISE--LQKASVDGWFKL 277
+ + V ++ + S +DF+G S + E L+ + W L
Sbjct: 335 E--IEVSVYHXGVLS-DDFLGYTSLPLWEQRLEDTTKTQWISL 454
>17516
Length = 453
Score = 33.1 bits (74), Expect = 0.39, Method: Composition-based stats.
Identities = 14/40 (35%), Positives = 24/40 (60%), Gaps = 1/40 (2%)
Frame = -3
Query: 500 TFCGTPDYIAPEIIAYQ-PYGKSVDWWAFGVLLYEMLAGQ 538
T GTP Y+APE++ + Y D ++ ++L+E+ GQ
Sbjct: 442 TLAGTPVYMAPEVLLQKGQYDMKADVYSLAIILWELWYGQ 323
>26009
Length = 886
Score = 32.7 bits (73), Expect = 0.49, Method: Compositional matrix adjust.
Identities = 41/167 (24%), Positives = 63/167 (37%), Gaps = 24/167 (14%)
Frame = +2
Query: 290 VPPEGSEANEELRQKFERAKISQGTKVPEEKTTNTVSKFDNNGNRDRMK-------LTDF 342
+PPE A+ +++ ER Q EE + TV ++G R K T
Sbjct: 212 LPPEVPPADLTVKKCDERDVGGQREVAVEESSATTVVSNQDDGGRGESKEDRSPRNSTSD 391
Query: 343 NFLMV-----------LGKGSFGKVMLSERKGTDELYAVKILKKDVVIQDDDVECTMVE- 390
N L + LG+G++GKV+L+ + T A+K+L K CT +
Sbjct: 392 NLLTLSLREHYDVCKELGRGTYGKVVLARCRHTGTQVALKLLPK---------SCTKLRE 544
Query: 391 -----KRVLALPGKPPFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHI 432
+ L + + FQT F E+ GDL I
Sbjct: 545 FQREFQLSYFLSPHANIIDTYNVAFQTRSSYVFAQEHAVLGDLFDAI 685
>02913
Length = 855
Score = 32.7 bits (73), Expect = 0.52, Method: Compositional matrix adjust.
Identities = 18/46 (39%), Positives = 26/46 (56%)
Frame = +3
Query: 626 DTSNFDKEFTRQPVELTPTDKLFIMNLDQNEFAGFSYTNPEFVINV 671
DTS FD +FTRQ +P D + +++Q F GF+Y P + V
Sbjct: 6 DTSQFDTKFTRQTPVDSPDDTILSDSINQ-VFKGFTYIAPSVLEEV 140
>13305
Length = 549
Score = 32.3 bits (72), Expect = 0.63, Method: Composition-based stats.
Identities = 15/45 (33%), Positives = 24/45 (53%), Gaps = 1/45 (2%)
Frame = +2
Query: 507 YIAPEIIAYQPYGKSVDWWAFGVLLYEMLA-GQAPFEGEDEDELF 550
++A E + Y D W+FGV+L+E+ G P+ D +LF
Sbjct: 23 WMAVESLFNNTYTTQSDVWSFGVVLWEIFTLGGTPYSSTDTQQLF 157
>26052
Length = 562
Score = 32.3 bits (72), Expect = 0.71, Method: Composition-based stats.
Identities = 16/28 (57%), Positives = 18/28 (64%)
Frame = -1
Query: 344 FLMVLGKGSFGKVMLSERKGTDELYAVK 371
F +LG GSFGKVM + K T E AVK
Sbjct: 379 FXKLLGVGSFGKVMALQHKDTGETLAVK 296
>29360
Length = 363
Score = 32.0 bits (71), Expect = 0.88, Method: Compositional matrix adjust.
Identities = 30/119 (25%), Positives = 55/119 (46%), Gaps = 5/119 (4%)
Frame = +3
Query: 361 RKGTDELYAVKILKKD-VVIQDDDVECTMVEKRVLALPGKPPFLTQLHSCFQTMDRLYFV 419
+KGT E+ A+KILK + +E +++++ F+ CFQ + V
Sbjct: 15 KKGTSEIVAIKILKNHPSYARQGQIEVSILQRLSQESADDYNFVRAF-ECFQHKNHTCLV 191
Query: 420 MEYVNGGDLMYHIQQVGRFKEPHAVFY----AAEIAIGLFFLQSKGIIYRDLKLDNVML 474
E + +Y + +F +P + Y ++ L L+ G+I+ DLK +N+ML
Sbjct: 192 FEMLEQN--LYDFLKQNKF-QPLPLKYIRPITQQVLTALRKLKQLGLIHADLKPENIML 359
>17637
Length = 447
Score = 30.8 bits (68), Expect = 1.9, Method: Compositional matrix adjust.
Identities = 20/79 (25%), Positives = 37/79 (46%), Gaps = 2/79 (2%)
Frame = +1
Query: 507 YIAPEIIAYQPYGKSVDWWAFGVLLYEMLA-GQAPFEGEDEDELFQSIME-HNVAYPKSM 564
+++ E + Y + D W+FGVL++EM G+ P+ D E+ + + + +A P +
Sbjct: 115 WLSLEALQKSHYNEGSDVWSFGVLMWEMCTLGKLPYAEIDPYEMEHYLKDGYRLAQPFNC 294
Query: 565 SKEAVAICKGLMTKHPGKR 583
E I P +R
Sbjct: 295 PDELFTIMAYCWASMPAER 351
>33692
Length = 426
Score = 29.6 bits (65), Expect = 3.8, Method: Composition-based stats.
Identities = 13/31 (41%), Positives = 15/31 (48%), Gaps = 1/31 (3%)
Frame = -1
Query: 50 CSHCTDFIWGFGKQGFQCQVCC-FVVHKRCH 79
C + WG QGFQC CC +VV H
Sbjct: 228 CRNLLSSFWGKVSQGFQCLNCCWYVVRNTLH 136
>36976
Length = 442
Score = 29.3 bits (64), Expect = 5.1, Method: Compositional matrix adjust.
Identities = 26/102 (25%), Positives = 46/102 (45%), Gaps = 1/102 (0%)
Frame = +1
Query: 77 RCHEFVTFSCPGADKGPASDDPRSKHKFKIHTYSSPTFCDHCGSLLYGLIHQGMKCDTCM 136
+C E + +C +GP SD+P + K + T + P CD C L DT +
Sbjct: 37 KCGEPSSATC----QGPGSDEPATSDKTXLSTAARPHVCDVCFKTFTTLSDHK---DTWL 195
Query: 137 MNVHKRC-VMNVPSLCGTDHTERRGRIYIQAHIDRDVLIVLV 177
++++++ V +V S T+ +E + I R L+ V
Sbjct: 196 IHINQKPFVCDVCSKTCTNSSELKRHKLIHTMTSRKNLVCDV 321
>36388
Length = 834
Score = 29.3 bits (64), Expect = 5.6, Method: Compositional matrix adjust.
Identities = 14/31 (45%), Positives = 18/31 (58%), Gaps = 4/31 (12%)
Frame = +2
Query: 58 WGFGKQGFQCQVCCFVVHK--RCH--EFVTF 84
WG+G F+C++CCF H CH F TF
Sbjct: 257 WGWGDHNFKCRICCFQFHWVLSCHLXXFQTF 349
>26304
Length = 1290
Score = 28.9 bits (63), Expect = 7.5, Method: Compositional matrix adjust.
Identities = 16/50 (32%), Positives = 24/50 (48%), Gaps = 7/50 (14%)
Frame = +3
Query: 193 DPYVKLKLIPD------PKSESKQKTKTIKCSLNPEW-NETFRFQLKESD 235
DPYVKL ++P P + ++ + NP W NETF + +D
Sbjct: 906 DPYVKLTVVPSKSYPEKPHHHRELRSSVCPSTTNPVWDNETFTLEAYVTD 1055
>08416
Length = 1551
Score = 28.5 bits (62), Expect = 9.2, Method: Compositional matrix adjust.
Identities = 21/63 (33%), Positives = 27/63 (42%), Gaps = 11/63 (17%)
Frame = -3
Query: 84 FSCPGADKGPASDDPRSKHKFKIHTYSSPTFCDHCGSL---------LYGLIHQGMK--C 132
F+C +K A + HK IHT + P CD CG + Y IH G + C
Sbjct: 958 FACDVCNKSFARRHHLTHHKL-IHTDNKPFVCDVCGKIKIIFKSXLKXYYXIHTGQQPVC 782
Query: 133 DTC 135
D C
Sbjct: 781 DVC 773
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000305355 | hsapiens_gene_ensembl | Protein kinase
C beta type (EC 2.7.11.13) (PKC-beta) (PKC-B).
[Source:Uniprot/SWISSPROT;Acc:P05771]
(673 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
18484 276 4e-88
30755 216 2e-56
18663 180 1e-45
25445 162 4e-40
03240 161 8e-40
00486 135 4e-32
26156 117 6e-32
27405 113 3e-25
31885 110 2e-24
25019 80 8e-24
12721 104 9e-23
26560 102 4e-22
17722 100 1e-21
06405 100 2e-21
09606 96 4e-20
13066 93 4e-19
15910 92 6e-19
18921 91 1e-18
14420 91 2e-18
00300 89 5e-18
21808 84 1e-16
01707 82 5e-16
01392 80 3e-15
21079 76 4e-14
13592 76 6e-14
16549 73 3e-13
01060 72 7e-13
14116 72 1e-12
13212 70 2e-12
00392 69 5e-12
14126 69 8e-12
04852 68 1e-11
19094 67 2e-11
32957 67 3e-11
29581 66 5e-11
27546 65 8e-11
09007 63 5e-10
28638 51 7e-10
38560 61 1e-09
04591 60 2e-09
26711 60 3e-09
07940 60 3e-09
21433 60 3e-09
37602 60 4e-09
11185 59 6e-09
35187 59 8e-09
01756 58 1e-08
12672 58 1e-08
29179 58 1e-08
17300 57 2e-08
01966 49 3e-08
11780 50 6e-08
19761 55 6e-08
07291 55 7e-08
00715 55 8e-08
33586 47 9e-08
29590 55 1e-07
31935 54 2e-07
12786 54 3e-07
03508 54 3e-07
30339 52 6e-07
19361 52 1e-06
11353 51 2e-06
30040 50 3e-06
22804 50 4e-06
01718 49 9e-06
26525 48 1e-05
17975 48 1e-05
20640 47 3e-05
19301 47 3e-05
20152 46 4e-05
04138 46 4e-05
17932 33 6e-05
17591 45 8e-05
07591 45 8e-05
07833 45 1e-04
30743 44 1e-04
27274 44 2e-04
16708 44 3e-04
03942 41 0.002
36305 41 0.002
18996 40 0.003
07836 40 0.003
02638 38 0.011
14477 37 0.030
12442 37 0.034
11404 36 0.043
18401 36 0.064
31120 35 0.14
22005 34 0.15
17253 33 0.29
13896 33 0.37
17516 33 0.39
26009 33 0.43
13305 32 0.63
26052 32 0.71
29360 32 0.93
17637 31 1.9
33692 30 3.8
36976 29 4.9
36388 29 6.0
26304 28 8.4
08416 28 8.8
>18484
Length = 635
Score = 276 bits (705), Expect(2) = 4e-88, Method: Compositional matrix adjust.
Identities = 126/161 (78%), Positives = 143/161 (88%)
Frame = +1
Query: 427 DLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFG 486
DLMY IQQ G+FKEP A FYAAEIA+GLFFL +GIIYRDLKLDNVMLDSEGHIKIADFG
Sbjct: 1 DLMYRIQQEGKFKEPVAAFYAAEIAVGLFFLHDQGIIYRDLKLDNVMLDSEGHIKIADFG 180
Query: 487 MCKENIWDGVTTKTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDE 546
MCKE + TT+TFCGTPDYIAPEI+ YQPY KSVDWWA+GVLL+EMLAGQ PF+GEDE
Sbjct: 181 MCKEGMTGDATTRTFCGTPDYIAPEIVLYQPYSKSVDWWAYGVLLFEMLAGQPPFDGEDE 360
Query: 547 DELFQSIMEHNVAYPKSMSKEAVAICKGLMTKHPGKRLGCG 587
DELF SI +HNV+YPK+MS+EAV++CKGL+ K+P KRLGCG
Sbjct: 361 DELFSSITDHNVSYPKAMSREAVSLCKGLLMKNPTKRLGCG 483
Score = 68.2 bits (165), Expect(2) = 4e-88, Method: Compositional matrix adjust.
Identities = 32/53 (60%), Positives = 39/53 (73%), Gaps = 1/53 (1%)
Frame = +2
Query: 584 LGCGPEGERDIKEHAFFRYIDWEKLERKEIQPPYKPKACGRN-AENFDRFFTR 635
LG GERDI++HAFFR I W+K++ E+QPPYKPK R AENFD+ FTR
Sbjct: 473 LGVVQNGERDIRDHAFFRRIVWDKIKSMEVQPPYKPKITDRRKAENFDKSFTR 631
>30755
Length = 1137
Score = 216 bits (550), Expect = 2e-56, Method: Compositional matrix adjust.
Identities = 102/215 (47%), Positives = 142/215 (66%), Gaps = 1/215 (0%)
Frame = +2
Query: 431 HIQQVGRFKEPHAVFYAAEIAIGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCKE 490
H+ F E FY AEI L +L S+GIIYRDLKL+N++LD +GHIK+ADFG+CKE
Sbjct: 2 HLSHERIFTEERTRFYGAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCKE 181
Query: 491 NIWDGVTTKTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELF 550
+I G TTKTFCGTP+Y+APE++ YG++VDWW GV++YEM+ G+ PF D D LF
Sbjct: 182 DITYGRTTKTFCGTPEYLAPEVLDDNDYGRAVDWWGTGVVMYEMICGRLPFYNRDHDVLF 361
Query: 551 QSIMEHNVAYPKSMSKEAVAICKGLMTKHPGKRLGCGPEGERDIKEHAFFRYIDWEKLER 610
I+ +V +P++++ EA ++ GL+ K P RLG G + ++I+ H FF I+W L +
Sbjct: 362 TLILVEDVKFPRNITDEAKSLLSGLLAKDPRNRLGGGQDDVKEIQAHPFFASINWTDLVQ 541
Query: 611 KEIQPPYKPKACG-RNAENFDRFFTRHPPVLTPPD 644
K+I PP+KP+ + FD FT LTPPD
Sbjct: 542 KKITPPFKPQVTSDTDTRYFDEEFTGESVELTPPD 646
>18663
Length = 600
Score = 180 bits (457), Expect = 1e-45, Method: Compositional matrix adjust.
Identities = 95/183 (51%), Positives = 118/183 (64%), Gaps = 11/183 (6%)
Frame = +2
Query: 499 KTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAPF------EGED---EDEL 549
TFCGTP+YIAPEI+ + YG SVDWWA GVLLYEMLAG++PF E D ED L
Sbjct: 2 STFCGTPNYIAPEILRGEDYGFSVDWWALGVLLYEMLAGRSPFDIAGASENPDQNTEDYL 181
Query: 550 FQSIMEHNVAYPKSMSKEAVAICKGLMTKHPGKRLGCGPEGE-RDIKEHAFFRYIDWEKL 608
FQ I+E + P+S+S +A ++ KG + K+P RLGC E DI H FF+ IDWE L
Sbjct: 182 FQVILEKTIRIPRSLSVKAASVLKGFLNKNPADRLGCHRESAFMDIVNHPFFKVIDWEML 361
Query: 609 ERKEIQPPYKPKA-CGRNAENFDRFFTRHPPVLTPPDQEVIRNIDQSEFEGFSFVNSEFL 667
ERK++ PP+KP+ R+ NF FT P LTP D VI +IDQSEFEGF +VN +
Sbjct: 362 ERKQVSPPFKPRLDSDRDLANFPIEFTGEPVQLTPDDDHVIDSIDQSEFEGFEYVNPLLM 541
Query: 668 KPE 670
E
Sbjct: 542 SLE 550
>25445
Length = 460
Score = 162 bits (410), Expect = 4e-40, Method: Compositional matrix adjust.
Identities = 86/162 (53%), Positives = 106/162 (65%), Gaps = 12/162 (7%)
Frame = -1
Query: 80 EFVTFSCPGADKGPASDDPRSKHKFKIHTYSSPTFCDHCGSLLYGLIHQGMKCDTCMMNV 139
EFV+F+CPGAD GP SD + HKFK HTY SPTFCDHCGSLLYGLIHQG+KCD+C MN
Sbjct: 460 EFVSFACPGADNGPDSDA-TNLHKFKAHTYGSPTFCDHCGSLLYGLIHQGLKCDSCDMNC 284
Query: 140 HKRCVMNVPSLCGTDHTERRGRIYIQAHIDRDVLIVLVRDAKNLVPMDPNGLSDPYVKL- 198
HKRC +VP LCG DHTERRGRIY++ L+V V++AK P++++
Sbjct: 283 HKRCEKHVPRLCGMDHTERRGRIYLRISPHGSKLLVNVKEAKKPC--------VPWIQMV 128
Query: 199 -----------KLIPDPKSESKQKTKTIKCSLNPEWNETFRF 229
+IP ++E TKTIK SLNP+W+ETF
Sbjct: 127 WPILIPK*S*FHMIPTKQTE----TKTIKSSLNPQWDETFTL 14
Score = 52.4 bits (124), Expect = 6e-07, Method: Compositional matrix adjust.
Identities = 26/69 (37%), Positives = 32/69 (46%)
Frame = -1
Query: 18 VRFARKGALRQKNVHEVKNHKFTARFFKQPTFCSHCTDFIWGFGKQGFQCQVCCFVVHKR 77
V FA GA + HKF A + PTFC HC ++G QG +C C HKR
Sbjct: 454 VSFACPGADNGPDSDATNLHKFKAHTYGSPTFCDHCGSLLYGLIHQGLKCDSCDMNCHKR 275
Query: 78 CHEFVTFSC 86
C + V C
Sbjct: 274 CEKHVPRLC 248
>03240
Length = 1683
Score = 161 bits (407), Expect = 8e-40, Method: Compositional matrix adjust.
Identities = 122/414 (29%), Positives = 181/414 (43%), Gaps = 56/414 (13%)
Frame = -3
Query: 298 NEELRQKFERAKISQGTKVPEEKTTNTVSKFDNNGNRDRMKLTDFNFLMVLGKGSFGKVM 357
NE + K Q ++ +K +N + R +M F + LG G+FG+V
Sbjct: 1402 NEMAKVKLSEEAARQMRRMLHQKESNYIRL-----KRAKMDKCMFEKIKTLGVGAFGEVS 1238
Query: 358 LSERKGTDELYAVKILKKDVVIQDDDVECTMVEKRVLALPGKPPFLTQLHSCFQTMDRLY 417
L + T LYA+K L+K V++ + V E+ +LA ++ +L+ FQ + LY
Sbjct: 1237 LCRKNDTGMLYAMKTLRKSDVLKRNQVAHVKAERDILA-EADNEWVVKLYYSFQDHNYLY 1061
Query: 418 FVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSKGIIYRDLKLDNVMLDSE 477
FVM+YV GGDLM + ++ EP A FY AE+ + + G I+RD+K DN+++D
Sbjct: 1060 FVMDYVPGGDLMGLLIRMEILDEPLARFYVAELVQAIESVHRMGFIHRDIKPDNILIDRN 881
Query: 478 GHIKIADFGMCKENIW---------DGVTTK----------------------------- 499
GHIK+ DFG+C W DG +
Sbjct: 880 GHIKLTDFGLCTGFRWTHNSKYYQRDGTHARQDSMEVKCQLDEQCQCEILKPLERRRKRE 701
Query: 500 ------TFCGTPDYIAPEIIA-YQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQS 552
+ GTP+YIAPE+++ Y DWW+ GV+L+EML G PF E
Sbjct: 700 QRCLAHSLVGTPNYIAPEVLSRLGGYTSVCDWWSVGVILFEMLVGHPPFYANTPAE---- 533
Query: 553 IMEHNVAYPKSMSKEAVAICKGLMTKHPGK----RLGCGPE------GERDIKEHAFFRY 602
Y K+ + I + P K RL CG + G +IK H FF
Sbjct: 532 -----TQYKVINWKDMLKIPRESNLSQPAKDLILRLCCGSDDRLGLNGAGEIKTHMFFAG 368
Query: 603 IDWEKLERKEIQPPYKPKA-CGRNAENFDRFFTRHPPVLTPPDQEVIRNIDQSE 655
+++E L ++ QPPY P + NFD P D + +RN D E
Sbjct: 367 VNFETLRKQ--QPPYVPNIRYATDTSNFD-----------PVDPDKLRNSDSEE 245
>00486
Length = 797
Score = 135 bits (341), Expect = 4e-32, Method: Compositional matrix adjust.
Identities = 64/172 (37%), Positives = 100/172 (58%), Gaps = 1/172 (0%)
Frame = -2
Query: 498 TKTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHN 557
T TFCGT +Y+APEI+ +GK+VDWW+ G L+Y+ML G PF E+ + I++
Sbjct: 787 THTFCGTIEYMAPEILTRTGHGKAVDWWSLGALMYDMLTGSPPFTAENRKKTIDKILKGK 608
Query: 558 VAYPKSMSKEAVAICKGLMTKHPGKRLGCGPEGERDIKEHAFFRYIDWEKLERKEIQPPY 617
+ P ++ EA + K L+ K+P +RLG G + IK+H FFR +W L + +PP+
Sbjct: 607 LNLPPYLTNEARGLIKKLLRKNPAERLGGGHDDSGPIKDHQFFRNTNWALLALRRAEPPF 428
Query: 618 KPKACG-RNAENFDRFFTRHPPVLTPPDQEVIRNIDQSEFEGFSFVNSEFLK 668
+P + FD FTR PV +P D + +I+Q F+GF+++ L+
Sbjct: 427 RPNVTSDEDTSQFDTKFTRQTPVDSPDDTILSDSINQV-FKGFTYIAPSVLE 275
>26156
Length = 479
Score = 117 bits (292), Expect(2) = 6e-32, Method: Compositional matrix adjust.
Identities = 54/112 (48%), Positives = 77/112 (68%)
Frame = -1
Query: 334 RDRMKLTDFNFLMVLGKGSFGKVMLSERKGTDELYAVKILKKDVVIQDDDVECTMVEKRV 393
R+++ LTDF L V+G+GS+ KV+ E K T +YA+K++KK++V D+D++ EK V
Sbjct: 407 RNKLGLTDFLLLRVIGRGSYAKVLQVEHKRTKRIYAMKVIKKELVNDDEDIDWVQTEKHV 228
Query: 394 LALPGKPPFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVF 445
PFL LHSCFQ+ RL+FV+E+VNGGDLM+H+Q+ R E HA F
Sbjct: 227 FETATNYPFLVGLHSCFQSESRLFFVIEFVNGGDLMFHMQRQRRLPEEHARF 72
Score = 39.7 bits (91), Expect(2) = 6e-32, Method: Composition-based stats.
Identities = 16/25 (64%), Positives = 20/25 (80%)
Frame = -3
Query: 445 FYAAEIAIGLFFLQSKGIIYRDLKL 469
FY+AEI + L FL +GI+YRDLKL
Sbjct: 75 FYSAEICLALNFLHKRGIVYRDLKL 1
>27405
Length = 532
Score = 113 bits (282), Expect = 3e-25, Method: Compositional matrix adjust.
Identities = 62/178 (34%), Positives = 99/178 (55%), Gaps = 4/178 (2%)
Frame = -3
Query: 352 SFGKVMLSERKGTDELYAVKILKKDVVIQDDDVECTMVEKRVLALPGK---PPFLTQLHS 408
FG+V + T ++YA+K L K + + E+ +L+L PF+ +
Sbjct: 530 GFGEVYGCRKADTGKMYAMKCLDKKRIKMKGGETLALNERIMLSLVSTGEGSPFIVCMTY 351
Query: 409 CFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSKGIIYRDLK 468
FQT ++L F+++ +NGGDL YH+ Q G F E FYAAE+ +GL + S+ ++YRDLK
Sbjct: 350 AFQTPEKLCFILDLMNGGDLHYHLSQHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLK 171
Query: 469 LDNVMLDSEGHIKIADFGMCKENIWDGVTTKTFCGTPDYIAPEIIAY-QPYGKSVDWW 525
N++LD GH++I+D G+ + + GT Y+APE++ Q Y S DW+
Sbjct: 170 PANILLDENGHVRISDLGLACD--FSKKKPHASVGTHGYMAPEVLMKGQAYDSSADWF 3
>31885
Length = 529
Score = 110 bits (274), Expect = 2e-24, Method: Compositional matrix adjust.
Identities = 58/146 (39%), Positives = 87/146 (59%), Gaps = 5/146 (3%)
Frame = -2
Query: 401 PFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSK 460
PFL L FQ + L+ V++ GGDL YH+QQ F+E FY ++A+ L +L+S+
Sbjct: 492 PFLVNLWYAFQDEEDLFMVVDLFLGGDLRYHMQQEVSFREDCVKFYLCQLALVLDYLRSQ 313
Query: 461 GIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTKTFCGTPDYIAPEIIAY----- 515
I++RD+K DN++LD +GH + DF + + D + T T GT Y+APE+
Sbjct: 312 KIVHRDIKPDNILLDEQGHCHVTDFNIATQLEDDELATST-SGTRPYMAPEVYGVAINER 136
Query: 516 QPYGKSVDWWAFGVLLYEMLAGQAPF 541
+ YG VDWW+ GV L+E+L + PF
Sbjct: 135 RGYGFPVDWWSLGVSLFELLKKRRPF 58
>25019
Length = 730
Score = 80.5 bits (197), Expect(2) = 8e-24, Method: Compositional matrix adjust.
Identities = 32/59 (54%), Positives = 44/59 (74%)
Frame = +3
Query: 470 DNVMLDSEGHIKIADFGMCKENIWDGVTTKTFCGTPDYIAPEIIAYQPYGKSVDWWAFG 528
+NV+LD +GH+K+ DFG+CKE I T TFCGT +Y+APEI+ +GK+VDWW+ G
Sbjct: 261 ENVLLDKDGHVKLTDFGLCKEAITGTRVTHTFCGTIEYMAPEILTRTGHGKAVDWWSLG 437
Score = 48.5 bits (114), Expect(2) = 8e-24, Method: Compositional matrix adjust.
Identities = 20/59 (33%), Positives = 34/59 (57%)
Frame = +1
Query: 527 FGVLLYEMLAGQAPFEGEDEDELFQSIMEHNVAYPKSMSKEAVAICKGLMTKHPGKRLG 585
+G L+Y+ML G PF E+ + I++ + P ++ EA + K L+ K+P +RLG
Sbjct: 433 WGALMYDMLTGSPPFTAENRKKTIDKILKGKLNLPPYLTNEARGLIKKLLRKNPAERLG 609
>12721
Length = 821
Score = 104 bits (260), Expect = 9e-23, Method: Compositional matrix adjust.
Identities = 49/144 (34%), Positives = 80/144 (55%)
Frame = +1
Query: 401 PFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSK 460
P + ++++ + D L+ VME++ GG L I R E L FL +
Sbjct: 256 PNIVEMYNSYLVNDELWVVMEFMEGGAL-TDIVTNNRMDEVQIATVCRACLKALAFLHAN 432
Query: 461 GIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTKTFCGTPDYIAPEIIAYQPYGK 520
G+I+RD+K D+++L +G +K+ DFG C + D K+ GTP ++APE+I+ PYG
Sbjct: 433 GVIHRDIKSDSILLSHDGKVKLXDFGFCAQVTQDLQKRKSLVGTPYWMAPEVISRLPYGP 612
Query: 521 SVDWWAFGVLLYEMLAGQAPFEGE 544
VD W+ G+++ EM+ + PF E
Sbjct: 613 EVDIWSLGIMVMEMIDAEPPFFNE 684
>26560
Length = 398
Score = 102 bits (255), Expect = 4e-22, Method: Compositional matrix adjust.
Identities = 48/123 (39%), Positives = 75/123 (60%), Gaps = 1/123 (0%)
Frame = -1
Query: 427 DLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFG 486
DL YH+ Q G F E FYAAE+ +GL + S+ ++YRDLK N++LD GH++I+D G
Sbjct: 398 DLHYHLSQHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLG 219
Query: 487 MCKENIWDGVTTKTFCGTPDYIAPEIIAY-QPYGKSVDWWAFGVLLYEMLAGQAPFEGED 545
+ + + GT Y+APE++ Q Y S DW++FG +LY++L G +PF +
Sbjct: 218 LACD--FSKKRPHASVGTHGYMAPEVLMKGQSYDSSADWFSFGCMLYKLLKGHSPFRQHN 45
Query: 546 EDE 548
+ +
Sbjct: 44 QGQ 36
>17722
Length = 680
Score = 100 bits (250), Expect = 1e-21, Method: Compositional matrix adjust.
Identities = 44/98 (44%), Positives = 65/98 (66%)
Frame = -3
Query: 522 VDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHNVAYPKSMSKEAVAICKGLMTKHPG 581
VDWW GV++YEM+ G+ PF D D LF+ I+ NV +P+++S+EA + GL+ K+P
Sbjct: 678 VDWWGTGVVMYEMMCGRLPFYNRDHDVLFELILLQNVKFPRNLSEEAKTLLSGLLAKNPK 499
Query: 582 KRLGCGPEGERDIKEHAFFRYIDWEKLERKEIQPPYKP 619
+RLG +IK H FF+ I+W+ L K+I PP+KP
Sbjct: 498 RRLGGSEADVTEIKTHPFFQCINWDDLAAKKITPPWKP 385
>06405
Length = 1965
Score = 100 bits (250), Expect = 2e-21, Method: Compositional matrix adjust.
Identities = 69/232 (29%), Positives = 116/232 (50%), Gaps = 4/232 (1%)
Frame = +1
Query: 324 TVSKFDNNGNRDRMKLTDFNFLMVLGKGSFGKVMLSERKGTDELYAVKILKKDVVIQDDD 383
TV +R ++ T+ LG G +G V + K +++ AVK LK+D + +D
Sbjct: 211 TVFGVSPEPDRWEIERTEIAMKHRLGGGQYGDVYEAMWKRYNKIVAVKTLKEDTMALNDF 390
Query: 384 VECTMVEKRVLALPGKPPFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKE-PH 442
+E + K + K P L QL Y V E++ G+L+ +++ R + P
Sbjct: 391 LEEAAIMKEM-----KHPNLVQLLGVCTREPPFYIVTEFMPHGNLLDYLRSSTREENGPT 555
Query: 443 AVFY-AAEIAIGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTKTF 501
A+ Y A +IA G+ +L++K I+RDL N ++ +K+ADFG+ + D T
Sbjct: 556 ALMYMATQIASGMAYLETKNFIHRDLAARNCLVADSNMVKVADFGLARLMKDDTYTAHIG 735
Query: 502 CGTP-DYIAPEIIAYQPYGKSVDWWAFGVLLYEMLA-GQAPFEGEDEDELFQ 551
P + APE +A+ + D WAFGVLL+E+ G +P+ G + E++
Sbjct: 736 AKFPIKWTAPEGLAFNRFSTRSDIWAFGVLLWELATYGMSPYPGVELTEVYH 891
>09606
Length = 1300
Score = 96.3 bits (238), Expect = 4e-20, Method: Compositional matrix adjust.
Identities = 75/294 (25%), Positives = 125/294 (42%), Gaps = 30/294 (10%)
Frame = -3
Query: 338 KLTDFNFLMVLGKGSFGKVMLSERKGTDELYAVKILKKDVVIQDDDVECTMVEKRVLALP 397
++ +F LGKG + RKGT A+ ++K + +V T+ ++ P
Sbjct: 1121 RMENFVLYEELGKGEHSIIYKGRRKGTINFVAIHCIEK---CKRPEVTNTVRMTHDISHP 951
Query: 398 GKPPFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFL 457
+ Q H ++T + L+ V+E GG L + Q E + + GL ++
Sbjct: 950 N----VVQFHEWYETSNHLWLVVELCTGGSLADILAQDHHLPETSIRDFGIHLVTGLHYI 783
Query: 458 QSKGIIYRDLKLDNVMLDSEGHIKIADFGMCK---ENI-------------WDGVTTKTF 501
S GI++ DL+ V+LD+ G +K ADFG+ K EN+ W+ + +
Sbjct: 782 HSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQWNIQSAEEM 603
Query: 502 ------CGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIME 555
G+P Y+APE+ D WA G + YEM +G PF GE D ++
Sbjct: 602 MKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSGHPPFLGETYDITKDKVLN 423
Query: 556 HNVAYPKSM--------SKEAVAICKGLMTKHPGKRLGCGPEGERDIKEHAFFR 601
PK S E + + + L+ K +RL + +HAF++
Sbjct: 422 KEFPLPKVKGSRLSAKPSPEFLNLLESLLQKDSTRRLSWA-----SLVKHAFWQ 276
>13066
Length = 551
Score = 92.8 bits (229), Expect = 4e-19, Method: Compositional matrix adjust.
Identities = 46/132 (34%), Positives = 74/132 (56%), Gaps = 4/132 (3%)
Frame = +3
Query: 401 PFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSK 460
P++ Q+HS Q + + M + GDL+ +IQ+VG KE A + ++ L +L S
Sbjct: 156 PYIIQIHSILQRXPKNFIFMRFAERGDLLTYIQEVGFVKEKQAKIWFYQMTTALNYLHSY 335
Query: 461 GIIYRDLKLDNVMLDSEGHIKIADFGM---CKENIWDGVTTKTFCGTPDYIAPEIIAYQP 517
+ +RDLK +N++L S ++K+ADFG C + ++T+CG+ Y APEI+ P
Sbjct: 336 DVAHRDLKCENILLSSHFNVKLADFGFACACITESGEKYMSRTYCGSAAYAAPEIVYGAP 515
Query: 518 YG-KSVDWWAFG 528
Y K D W+ G
Sbjct: 516 YAPKVADAWSLG 551
>15910
Length = 1361
Score = 92.0 bits (227), Expect = 6e-19, Method: Compositional matrix adjust.
Identities = 53/165 (32%), Positives = 91/165 (55%), Gaps = 7/165 (4%)
Frame = +2
Query: 427 DLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSKGIIYRDLKLDNVM---LDSEGHIKIA 483
+L I G++ E A ++I G+ ++ + G+++RDLK +N++ + + +K+A
Sbjct: 422 ELFDRIVTRGQYTEKDAARAISDILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLA 601
Query: 484 DFGMCKENIWDGVTTKTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEG 543
DFG+ + I V T CGTP Y APE++ Y SVD W+ GV+ Y +L G PF
Sbjct: 602 DFGLSR-IIEPEVQMSTVCGTPGYCAPEVLKGDKYTPSVDMWSVGVIAYILLCGYEPFFA 778
Query: 544 EDEDELFQSIM----EHNVAYPKSMSKEAVAICKGLMTKHPGKRL 584
E+E E+++ I+ + + Y +S+ A + + L+ P KRL
Sbjct: 779 ENEFEMYRKIIKGEYKFDEEYWSEISENAKDVVRKLLVIDPKKRL 913
>18921
Length = 697
Score = 91.3 bits (225), Expect = 1e-18, Method: Compositional matrix adjust.
Identities = 60/202 (29%), Positives = 101/202 (50%), Gaps = 3/202 (1%)
Frame = +2
Query: 342 FNFLMVLGKGSFGKVMLSERKGTDELYAVKILKKDVVIQDDDVECTMVEKRVLALPGKPP 401
F+ L LG+GS+G V S K T ++ A+K + D +Q+ E +++++
Sbjct: 35 FDILGKLGEGSYGSVFKSLHKETGQVLAIKQVPVDTDLQEIIKEISIMQQ------CDSK 196
Query: 402 FLTQLHSCFQTMDRLYFVMEYVNGG---DLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQ 458
++ + + + L+ VMEY G D+M + +E + Y GL +L
Sbjct: 197 YIVKYYGSYFKNTDLWIVMEYCGAGSVSDIMRLRNKTLVEREIATILYYT--LKGLXYLH 370
Query: 459 SKGIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTKTFCGTPDYIAPEIIAYQPY 518
S+ I+RD+K N++L++EGH K+ADFG+ + T GTP ++APE+I Y
Sbjct: 371 SRRKIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTPYWMAPEVIQEIGY 550
Query: 519 GKSVDWWAFGVLLYEMLAGQAP 540
D W+ G+ EM G+ P
Sbjct: 551 DCVADIWSLGITALEMAEGKPP 616
>14420
Length = 528
Score = 90.5 bits (223), Expect = 2e-18, Method: Compositional matrix adjust.
Identities = 45/145 (31%), Positives = 75/145 (51%)
Frame = +2
Query: 401 PFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSK 460
P + + + L+ VME++ GG L + + E E L FL
Sbjct: 80 PNIVNYLDSYLVGEELWVVMEFLAGGSLTDVVTETC-MDEGQIAAVCRECLQALEFLHEN 256
Query: 461 GIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTKTFCGTPDYIAPEIIAYQPYGK 520
+I+RD+K DN++L +G +K+ DFG C + + T GTP ++APE++ + YG
Sbjct: 257 QVIHRDIKSDNILLGMDGSVKLTDFGFCAQLSPEQSKRSTMVGTPYWMAPEVVTRKQYGP 436
Query: 521 SVDWWAFGVLLYEMLAGQAPFEGED 545
+VD W+ GV+ EM+ G+ P+ E+
Sbjct: 437 TVDIWSLGVMCIEMIEGEPPYLNEN 511
>00300
Length = 2318
Score = 89.4 bits (220), Expect = 5e-18, Method: Compositional matrix adjust.
Identities = 67/249 (26%), Positives = 113/249 (45%), Gaps = 13/249 (5%)
Frame = -1
Query: 348 LGKGSFGKVMLSERKGTDELYAVKILKKDVVIQDDDVECT--MVEKRVLALPGKPPFLTQ 405
+G+G FGKV + T EL A+K +K Q +D++ M ++ + + L +
Sbjct: 1634 IGEGQFGKVYTAVNMSTGELMALKEMK----FQPNDLQQLREMCDEIKIFEGIQHENLVK 1467
Query: 406 LHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVF--YAAEIAIGLFFLQSKGII 463
+ D + MEY + G I++ + P + Y EI + + L I+
Sbjct: 1466 YYGVEVHKDEMLMFMEYCDTGT----IEEAAKMGLPEYLIRRYTREIVLAVNHLHENSIV 1299
Query: 464 YRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTT----KTFCGTPDYIAPEIIAYQP-- 517
+RD+K N+ L S GH+K+ DFG C + T GT Y+APE+
Sbjct: 1298 HRDIKGANIFLTSNGHVKLGDFG-CSVKLKSHTTMPGEFHNLVGTTAYMAPEVFTQNDQG 1122
Query: 518 -YGKSVDWWAFGVLLYEMLAGQAPFEGEDEDE--LFQSIMEHNVAYPKSMSKEAVAICKG 574
YG++ D W+ G ++ EM G+ P+ D + +++ + H A P S+S E
Sbjct: 1121 GYGRAADIWSLGCVVIEMATGKRPWHDLDNNYQIMYKVGIGHKPAVPDSLSVEGKHFLDL 942
Query: 575 LMTKHPGKR 583
+M P +R
Sbjct: 941 IMCHDPAQR 915
>21808
Length = 1011
Score = 84.3 bits (207), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 56/196 (28%), Positives = 94/196 (47%), Gaps = 3/196 (1%)
Frame = +1
Query: 369 AVKILKKDVVIQDDDVECTMVEKRVLALPGKPPFLTQLHSCFQTMDRLYFVMEYVNGGDL 428
A+K LK + D + + K++ + P L QL++ D ++ + E + G L
Sbjct: 31 AIKTLKSGTMDPKDFLAEAQIMKKL-----RHPKLIQLYAVCTQDDPIFIITELMKNGSL 195
Query: 429 MYHIQQVGR-FKEPHAVFYAAEIAIGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGM 487
+ +Q GR K P + A+IA G+ +L+S+ I+RDL N+++ +KIADFG+
Sbjct: 196 LEFLQGKGRVLKLPALIDIGAQIACGMAYLESQNYIHRDLAARNILVSDNNTVKIADFGL 375
Query: 488 CKENIWDGVTTKTFCGTP-DYIAPEIIAYQPYGKSVDWWAFGVLLYEMLA-GQAPFEGED 545
+ D + P + APE Y + D W+FG+LL E + G+ P+ G
Sbjct: 376 ARVIKEDEYEARVGARFPIKWTAPEAANYNRFTIKSDVWSFGILLTETVTYGRVPYPGMT 555
Query: 546 EDELFQSIMEHNVAYP 561
E+ + EH P
Sbjct: 556 NAEVLHQV-EHGYRMP 600
>01707
Length = 757
Score = 82.4 bits (202), Expect = 5e-16, Method: Compositional matrix adjust.
Identities = 65/207 (31%), Positives = 102/207 (49%), Gaps = 5/207 (2%)
Frame = +1
Query: 348 LGKGSFGKVMLSERKGTDELYAVKILKKDVVIQDDDV--ECTMVEKRVLALPGKPPFLTQ 405
+G+GS+G V K T +L A+K K V +DD + + M E R+L K P L +
Sbjct: 88 IGEGSYGVVFKCRNKETSQLVAIK---KFVESEDDPLIKKIAMREIRMLK-QLKHPNLVR 255
Query: 406 LHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGR-FKEPHAVFYAAEIAIGLFFLQSKGIIY 464
L F+ RL+ V +YV+ L+ + + R EP + + + F I+
Sbjct: 256 LIEVFRRKKRLHLVFDYVDH-TLLNELDRYPRGLPEPMVKRIIYQTLLAVNFCHQYNTIH 432
Query: 465 RDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTKTFCGTPDYIAPE-IIAYQPYGKSVD 523
RD+K +N+++ +G +K+ DFG + G + T Y APE ++ YG VD
Sbjct: 433 RDVKPENILITRQGQVKLCDFGFARILTGPGDEYTDYVATRWYRAPELLVGDTQYGPPVD 612
Query: 524 WWAFGVLLYEMLAGQAPFEGE-DEDEL 549
WA G + E+L GQA + G D D+L
Sbjct: 613 VWAIGCVFAELLTGQALWPGRSDVDQL 693
>01392
Length = 1806
Score = 79.7 bits (195), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 61/180 (33%), Positives = 84/180 (46%), Gaps = 32/180 (17%)
Frame = -1
Query: 436 GRFKEPHAVFYAAEIAIGLFFLQSKGIIYRDLKLDNVM---LDSEGHIKIADFGMCKENI 492
G E A IA L FL SKGI +RDLK +N++ LD +KI DF +
Sbjct: 1806 GHLCEREASLVVRHIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGIS 1627
Query: 493 WDGVTTKTF-----CGTPDYIAPEIIAYQ-----PYGKSVDWWAFGVLLYEMLAGQAPFE 542
DG TKT G+ +Y+APE++ Y K D W+ G++LY ML G PF
Sbjct: 1626 CDGDGTKTPELLTPVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILYIMLCGYPPFY 1447
Query: 543 ---GED------------EDELFQSIMEHNVAYPK----SMSKEAVAICKGLMTKHPGKR 583
GED +D LF SI + + +P S+S A + + L+ + P KR
Sbjct: 1446 GQCGEDCGWNRGEACHDCQDMLFNSIQDGHYKFPSQEWTSISSSAKDLIRHLLVREPRKR 1267
>21079
Length = 878
Score = 76.3 bits (186), Expect = 4e-14, Method: Compositional matrix adjust.
Identities = 45/143 (31%), Positives = 76/143 (53%), Gaps = 3/143 (2%)
Frame = +1
Query: 401 PFLTQLHSCFQTMDRLYFVMEYVNGGDLMYH-IQQVGRFKEPHAVFYAAEIAIGLFFLQS 459
P L L F+ + VME+V G+L I+ E V + +I G+ ++ +
Sbjct: 4 PKLLMLWDAFEAPRTMVLVMEFVGAGELFERVIRDDFVLTERDCVHFVRQICSGVGYMHT 183
Query: 460 KGIIYRDLKLDNVML--DSEGHIKIADFGMCKENIWDGVTTKTFCGTPDYIAPEIIAYQP 517
+ I++ DLK +NV+ D+ IKI DFG+ + G + + GTP++IAPE++ Y
Sbjct: 184 QSILHLDLKPENVLCVSDNSNQIKIIDFGLAR-FYKPGDSLQVLFGTPEFIAPEVVNYDE 360
Query: 518 YGKSVDWWAFGVLLYEMLAGQAP 540
+ D W+ GV+ Y +L+G +P
Sbjct: 361 INFTTDMWSIGVICYILLSGLSP 429
>13592
Length = 980
Score = 75.9 bits (185), Expect = 6e-14, Method: Compositional matrix adjust.
Identities = 66/249 (26%), Positives = 113/249 (45%), Gaps = 12/249 (4%)
Frame = +2
Query: 348 LGKGSFGKVMLSERKGTDELYAVKILKKDVVIQDDDVECTM-VEKRVLALPG-KPPFLTQ 405
+G+G FGKV + T EL A+K ++ IQ + V + + L G K L +
Sbjct: 8 IGQGRFGKVYTAVNNNTGELMAMK----EIAIQPGETRALKNVAEELKILEGIKHKNLVR 175
Query: 406 LHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSKGIIYR 465
+ + L ME + G L ++ G E + + A++ G+ L GI++R
Sbjct: 176 YYGIEVHREELLIFMELCSEGTLESLVELTGGLPEALSRRFTAQLLSGVAELHKHGIVHR 355
Query: 466 DLKLDNVML-DSEGHIKIADFGMCKENIWDGVTT----KTFCGTPDYIAPEIIA---YQP 517
D+K N+ L D +K+ DFG + I T + + GT Y+APE+
Sbjct: 356 DIKTANIFLVDGSNSLKLGDFGSAVK-IQAHTTVPGELQGYVGTQAYMAPEVFTKTNSDG 532
Query: 518 YGKSVDWWAFGVLLYEMLAGQAPFEGEDED--ELFQSIMEHNVAYPKSMSKEAVAICKGL 575
+G+ D W+ G ++ EM +G+ P+ D + +F+ M P+S+S+E
Sbjct: 533 HGRLADIWSVGCVVVEMASGKRPWAQFDSNFQIMFKVGMGEKPQAPESLSQEGHDFIDHC 712
Query: 576 MTKHPGKRL 584
+ P +RL
Sbjct: 713 LQHDPKQRL 739
>16549
Length = 607
Score = 73.2 bits (178), Expect = 3e-13, Method: Composition-based stats.
Identities = 32/89 (35%), Positives = 59/89 (66%), Gaps = 2/89 (2%)
Frame = +2
Query: 191 LSDPYVKLKLIPDPKSESKQKTKTIKCSLNPEWNETFRFQLKESD-KDRRLSVEIWDWDL 249
L PYVK L+PDP+ ++K+KTK +K S++P +NE ++++KE++ + R L V +WD D+
Sbjct: 56 LPSPYVKTYLLPDPEKQTKRKTKIVKHSVHPTFNEVLQYRMKETETRHRTLQVTVWDHDM 235
Query: 250 TSRNDFMGSLSFGISELQKA-SVDGWFKL 277
N+F+G++ + +L+ + W+ L
Sbjct: 236 LKENNFLGAVYLRLRDLELSDDTAKWYTL 322
>01060
Length = 1800
Score = 72.0 bits (175), Expect = 7e-13, Method: Compositional matrix adjust.
Identities = 61/221 (27%), Positives = 101/221 (45%), Gaps = 8/221 (3%)
Frame = +1
Query: 339 LTDFNFLMVLGKGSFGKVMLSERKGTDELYAVKILKKDVVIQDDDVECTMVEKRVLALPG 398
LTDF +G+G++G V + T A+K K + +D V + + + +
Sbjct: 79 LTDFQ---KIGEGTYGVVYKCRHRATGRKLAMK--KIRLRGSEDGVPSSAIREIAMLREL 243
Query: 399 KPPFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAV------FYAAEIAI 452
+ + L +RL+ V E+++ MY + +F E + Y +I
Sbjct: 244 RHTNIVCLEDVIMEDERLFLVFEFLSMDLKMY----IDKFPEGVVLDRRLVKSYVFQIVT 411
Query: 453 GLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTKTFCGTPDYIAPEI 512
G+ F + I++RDLK N++++ G IKIADFGM + T Y APEI
Sbjct: 412 GIXFCHQRRIVHRDLKPQNLLINHTGAIKIADFGMARTFALPVRAYTHEVVTLWYRAPEI 591
Query: 513 I-AYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDE-DELFQ 551
+ Y VD W+ G + +ML F+G+ E D+LF+
Sbjct: 592 LMGASKYSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFK 714
>14116
Length = 1017
Score = 71.6 bits (174), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 70/255 (27%), Positives = 115/255 (45%), Gaps = 16/255 (6%)
Frame = -1
Query: 298 NEELRQK--FERAKISQGTKVPEEKTTNTVSKFDNNGNRDRMKLTDFNFLMV---LGKGS 352
N E R+ F R + +P + K N + L D FL + +GKG+
Sbjct: 765 NLEARENDYFNRLDVQGAEAMPLLHIDEDMMKLIENESL----LIDREFLTMGEEIGKGN 598
Query: 353 FGKV-----MLSERKGTDELYAVKILKKDVVIQDDDVECTMVEKRVLALPGKPPFLTQLH 407
FG V L E+KG D L AVK L + ++ +++ + E ++ LT +
Sbjct: 597 FGCVKRGFLTLPEQKG-DILVAVKTLHNNNP-REIELQSFLQEALIMKDFHHSNVLTLIG 424
Query: 408 SCFQTMDRLYFVMEYVNGGDLMYHI---QQVGRFKEPHAVFYAAEIAIGLFFLQSKGIIY 464
C D V+ ++ GDL+ +I Q K+ + Y +IA G+ +L ++
Sbjct: 423 ICLNLDDMPLVVLPFMKHGDLLTYIRDDQHQPTIKD--LIMYGVDIARGMDYLAGLKFVH 250
Query: 465 RDLKLDNVMLDSEGHIKIADFGMCK---ENIWDGVTTKTFCGTPDYIAPEIIAYQPYGKS 521
RDL N MLD + H+K+ADFG+ + E + K ++A E + Y
Sbjct: 249 RDLAARNCMLDEDFHVKVADFGLARDIYEKEYYSSENKKAKLPVKWMALESLEKGNYDSK 70
Query: 522 VDWWAFGVLLYEMLA 536
D W++GV+L+E+L
Sbjct: 69 TDVWSYGVVLWELLT 25
>13212
Length = 1067
Score = 70.5 bits (171), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 36/108 (33%), Positives = 55/108 (50%), Gaps = 5/108 (4%)
Frame = -1
Query: 438 FKEPHAVFYAAEIAIGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVT 497
E + E+ + L FL +I+RD+K NV+L +G +K+ADFG+ +N
Sbjct: 989 MTEAQICYVCHEMCMALDFLHRHHVIHRDIKAGNVLLTIDGEVKLADFGVSAKNTQTQQK 810
Query: 498 TKTFCGTPDYIAPEIIAYQ-----PYGKSVDWWAFGVLLYEMLAGQAP 540
TF GTP ++APE++ + PY D W+ GV L E + P
Sbjct: 809 RDTFIGTPYWMAPEVVLCETLKDTPYDFKADIWSLGVTLIEFAQIEPP 666
>00392
Length = 668
Score = 68.9 bits (167), Expect = 5e-12, Method: Compositional matrix adjust.
Identities = 44/162 (27%), Positives = 90/162 (55%), Gaps = 7/162 (4%)
Frame = +3
Query: 416 LYFVMEYVNGGDLMYHIQQVGRFKEPHAVF---YAAEIAIGLFFLQSKG--IIYRDLKLD 470
+ V E + G L +++ RFK+P+ + ++ GL+FL ++ +I+RDLK D
Sbjct: 171 IILVTELMTSGTLKTYLK---RFKKPNVKILKNWCRQVLKGLYFLHTRTPPVIHRDLKCD 341
Query: 471 NVMLDS-EGHIKIADFGMCKENIWDGVTTKTFCGTPDYIAPEIIAYQPYGKSVDWWAFGV 529
N+ + G +KI D G+ + + K+ GTP+++APE+ + Y ++VD +AFG+
Sbjct: 342 NIFITGPTGSVKIGDLGLA--TLKNQSFAKSVIGTPEFMAPEMYE-EHYDEAVDVYAFGM 512
Query: 530 LLYEMLAGQAPF-EGEDEDELFQSIMEHNVAYPKSMSKEAVA 570
+ EM + + P+ E + ++++ + + P+++ K A+
Sbjct: 513 CMLEMASSEYPYSECSNAAQIYKRVT--SGVLPEALDKVAIT 632
>14126
Length = 1265
Score = 68.6 bits (166), Expect = 8e-12, Method: Compositional matrix adjust.
Identities = 36/103 (34%), Positives = 58/103 (56%)
Frame = +3
Query: 453 GLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTKTFCGTPDYIAPEI 512
G+ FL S I++RDLK N+++ +G +K+ADFG+ + + T T T Y +PE+
Sbjct: 552 GVDFLHSNRIVHRDLKPQNLLISKDGRLKLADFGLARIYSFHMALT-TVVVTLWYRSPEV 728
Query: 513 IAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIME 555
+ YG SVD W+ G + E+ +A F+G E + + I E
Sbjct: 729 LMQAEYGTSVDIWSCGCIFAELFTRRALFKGSSEFDQLKKIFE 857
>04852
Length = 1462
Score = 67.8 bits (164), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 65/246 (26%), Positives = 110/246 (44%), Gaps = 31/246 (12%)
Frame = +1
Query: 369 AVKILKKDV--VIQDDDVECTMVEKRVLALPGKPPFLTQLHSCFQTMDRLYFVMEYVNGG 426
AVK+L+ V V + D V+ V K V + + L C Q L+ ++E+ G
Sbjct: 31 AVKMLRDIVTAVEEQDFVQELQVMKAVKKMGSHINIVNFLGCCTQG-GPLWVIVEFAKNG 207
Query: 427 DLMYHIQQ-------VGRFKEP------------------HAVFYAAEIAIGLFFLQSKG 461
+L ++ G+F P + + YA +IA G+ FL S+
Sbjct: 208 NLRDFLESCRDGINGYGKFVSPQDPGWYTKTPGGHVIRRKNLLSYAFQIARGMEFLASRK 387
Query: 462 IIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTKTFCGTP-DYIAPEIIAYQPYGK 520
I+RDL NV++ E +KIADFG+ + D ++ P ++APE + Y
Sbjct: 388 CIHRDLAARNVLVTEEHVLKIADFGLSRTG--DYYKKRSGGRLPVKWMAPEALFDMRYTT 561
Query: 521 SVDWWAFGVLLYEMLA-GQAPFEGEDEDELFQSIME--HNVAYPKSMSKEAVAICKGLMT 577
D W+FGV+L+E+ + G P+ +EL+ +++ + + P+ S AI +
Sbjct: 562 KSDVWSFGVVLWEIFSLGGMPYASIPNEELYSKLLDDAYRMPRPELASGNLYAIMERCWL 741
Query: 578 KHPGKR 583
P R
Sbjct: 742 NRPSDR 759
>19094
Length = 898
Score = 67.4 bits (163), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 34/90 (37%), Positives = 50/90 (55%)
Frame = +1
Query: 453 GLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTKTFCGTPDYIAPEI 512
GL +L S+ I+RD+K N++L++EGH K+ADFG+ + T GTP ++APE+
Sbjct: 94 GL*YLHSRRKIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTPYWMAPEV 273
Query: 513 IAYQPYGKSVDWWAFGVLLYEMLAGQAPFE 542
I Y D W+ G+ EM G E
Sbjct: 274 IQEIGYDCVADIWSLGITALEMAEGNLHME 363
>32957
Length = 645
Score = 66.6 bits (161), Expect = 3e-11, Method: Composition-based stats.
Identities = 28/54 (51%), Positives = 37/54 (68%)
Frame = +3
Query: 485 FGMCKENIWDGVTTKTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQ 538
F +C E G T+TFCGT +Y+APE+ + YGK VDWW G+LL+E+LA Q
Sbjct: 3 FALCVEK--SGGRTRTFCGTREYMAPEVHERKEYGKEVDWWGLGILLHELLAAQ 158
>29581
Length = 1278
Score = 65.9 bits (159), Expect = 5e-11, Method: Compositional matrix adjust.
Identities = 52/222 (23%), Positives = 91/222 (40%), Gaps = 31/222 (13%)
Frame = -2
Query: 411 QTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSKGIIYRDLKLD 470
+++D L+ VMEY F E ++ GL +L II+RDLK+
Sbjct: 1139 KSLDSLFLVMEYCEQDLASLLDNMPAPFSESQVKCIVLQLLKGLRYLHEAFIIHRDLKVS 960
Query: 471 NVMLDSEGHIKIADFGMCKENIWDGVTTKTFCGTPDYIAPEII-AYQPYGKSVDWWAFGV 529
N+++ +G +KIADFG+ + T Y APE++ + + ++D W+ G
Sbjct: 959 NLLMTDKGCVKIADFGLARNYGKPQKPMTPKVVTLWYRAPELLFGSKTHSTAIDMWSAGC 780
Query: 530 LLYEMLAGQAPFEGEDEDELFQSIME-----HNVAYP----------------------- 561
+L E+L + G + + + IME ++ +P
Sbjct: 779 ILGELLGHKPLMPGRSDLQQIELIMELLGTPNDTIWPGFSQLPAFEQFTLKKQPYNNLRH 600
Query: 562 --KSMSKEAVAICKGLMTKHPGKRLGCGPEGERDIKEHAFFR 601
+S+ + + GL HP KR D EH++F+
Sbjct: 599 TFPWLSESGIRLLNGLFMYHPQKR-----ATAEDCLEHSYFK 489
>27546
Length = 426
Score = 65.1 bits (157), Expect = 8e-11, Method: Compositional matrix adjust.
Identities = 30/89 (33%), Positives = 50/89 (56%)
Frame = -1
Query: 401 PFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSK 460
P + Q+HS Q +++ M Y GD++ HI++ G E + ++A L +L S
Sbjct: 300 PNIIQIHSILQRGPKIFIFMRYAEKGDMLSHIKKTGPIDEAQTKVWFFQMAKALQYLHSH 121
Query: 461 GIIYRDLKLDNVMLDSEGHIKIADFGMCK 489
I +RDLK +N++L ++KIADFG +
Sbjct: 120 DIAHRDLKCENILLSKRLNVKIADFGFAR 34
>09007
Length = 1440
Score = 62.8 bits (151), Expect = 5e-10, Method: Compositional matrix adjust.
Identities = 57/251 (22%), Positives = 106/251 (42%), Gaps = 15/251 (5%)
Frame = -1
Query: 348 LGKGSFGKV---MLSERKGTDELYAVKILKKDVVIQDDDVECTMVEKRVLALPGKPPFLT 404
LG+G FG V + + G AVK L KD + +D + + E ++ + +
Sbjct: 855 LGQGHFGTVRQAIWTAESGEKVQVAVKCLSKDKIHKDG--QEFLKETAIMQMLDHENIVR 682
Query: 405 QLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGR---FKEPHAVFYAAEIAIGLFFLQSKG 461
+ V E L+ +++V F P ++ ++ G+ +L+SK
Sbjct: 681 VYGVVMDNGADIMLVTELAPMRSLLECVKEVSARVDFSVPRLCDFSQQVCDGMSYLESKR 502
Query: 462 IIYRDLKLDNVMLDSEGHIKIADFGM-----CKENIWDGVTTKTFCGTPDYIAPEIIAYQ 516
+++RDL N++L S+ +KI+D G+ + + T + APE
Sbjct: 501 LVHRDLAARNILLFSKSKVKISDVGVSGALGAGKEYYQSQQTIHLQNAVAWCAPESFRNL 322
Query: 517 PYGKSVDWWAFGVLLYEMLA-GQAPFEGEDEDELFQSI---MEHNVAYPKSMSKEAVAIC 572
+ + D WAFGVLL+E G P+ G + ++ +++ + P KE A+
Sbjct: 321 CFSSASDVWAFGVLLWEFFTHGFQPWAGLNGQQIMEAVDAPQSQRLEQPDLCPKEYYAVM 142
Query: 573 KGLMTKHPGKR 583
+ P +R
Sbjct: 141 LKCWEQEPQRR 109
>28638
Length = 1458
Score = 50.8 bits (120), Expect(2) = 7e-10, Method: Compositional matrix adjust.
Identities = 32/103 (31%), Positives = 55/103 (53%), Gaps = 7/103 (6%)
Frame = -1
Query: 446 YAAEIAIGLFFLQS--KGIIYRDLKLDNVMLDS--EGHIKIADFGM-CK--ENIWDGVTT 498
+A ++ L FL + II+ DLK +N++L + IKI DFG C+ + I+ + +
Sbjct: 822 FAQQLCTALLFLATPEMNIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQS 643
Query: 499 KTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAPF 541
+ Y +PE++ PY ++D W+ G +L EM G+ P
Sbjct: 642 RF------YRSPEVLLGVPYDLAIDMWSLGCILVEMHTGEPPL 532
Score = 30.8 bits (68), Expect(2) = 7e-10, Method: Compositional matrix adjust.
Identities = 21/76 (27%), Positives = 36/76 (47%), Gaps = 1/76 (1%)
Frame = -3
Query: 347 VLGKGSFGKVMLSERKGTDELYAVKILK-KDVVIQDDDVECTMVEKRVLALPGKPPFLTQ 405
++GKGSFG+V+ + G E A+KI+K K + +E ++E ++ +
Sbjct: 1126 LIGKGSFGQVVKAYDHGDQEQVAIKIIKNKKPFLNQAQIEVKLLELMNRHDADNXYYIVR 947
Query: 406 LHSCFQTMDRLYFVME 421
L F + L V E
Sbjct: 946 LKRHFMFRNHLCLVFE 899
>38560
Length = 479
Score = 61.2 bits (147), Expect = 1e-09, Method: Composition-based stats.
Identities = 30/86 (34%), Positives = 46/86 (53%), Gaps = 1/86 (1%)
Frame = -3
Query: 500 TFCGTPDYIAPEIIAYQPY-GKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHNV 558
T CG+P Y APE+I+ Y G D W+ GVLLY +L G PF+ E L Q +
Sbjct: 408 TCCGSPAYAAPELISGLEYLGSEADIWSMGVLLYALLCGYLPFDDEKXSHL*QKNQKRKD 229
Query: 559 AYPKSMSKEAVAICKGLMTKHPGKRL 584
P+ +S++ + +G++ P R+
Sbjct: 228 EVPEWLSEDTTKLLEGMLQTDPSHRI 151
>04591
Length = 1117
Score = 60.5 bits (145), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 31/109 (28%), Positives = 58/109 (53%), Gaps = 1/109 (0%)
Frame = -2
Query: 448 AEIAIGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTKTFCGTPDY 507
+++ GLF++ +K I++RD+K N++L +G +K+ADFG+ + + T T Y
Sbjct: 876 SQLLNGLFYIHTKQILHRDIKAANILLTRDGVLKLADFGLSRPWVKSKRLTNRVV-TLWY 700
Query: 508 IAPE-IIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIME 555
PE ++ + YG +D W G ++ EM + + +G E I +
Sbjct: 699 RPPELLLGEREYGPEIDMWGVGCIMAEMWSRKPLMQGRSEQHQLSLITD 553
>26711
Length = 405
Score = 60.1 bits (144), Expect = 3e-09, Method: Composition-based stats.
Identities = 29/94 (30%), Positives = 55/94 (58%), Gaps = 2/94 (2%)
Frame = -2
Query: 457 LQSKGIIYRDLKLDNVML--DSEGHIKIADFGMCKENIWDGVTTKTFCGTPDYIAPEIIA 514
+ ++G+++ DLK N++L D +++ DFG+ ++ ++ T GTP + +PE +
Sbjct: 368 VHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARK-LYPPQETFLNHGTPGFTSPEALD 192
Query: 515 YQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDE 548
+P + D W GVL Y +L+GQ+PF+ + E
Sbjct: 191 VKPISTASDVWGVGVLAYILLSGQSPFQADSATE 90
>07940
Length = 1336
Score = 60.1 bits (144), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 38/111 (34%), Positives = 60/111 (54%), Gaps = 3/111 (2%)
Frame = -3
Query: 444 VFYAAEIAIGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTKTFCG 503
+ YA ++A G+ +L SK I+RDL NV++ E +KIADFG+ + KT G
Sbjct: 338 ISYAYQVARGMEYLASKQCIHRDLAARNVLVAEEYVLKIADFGLTRNLQQFDYYRKTTDG 159
Query: 504 T--PDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLA-GQAPFEGEDEDELFQ 551
++APE + + Y D W++GVLL+E+ G P+ ++LF
Sbjct: 158 RLPVKWMAPEALFDRKYTSKSDVWSYGVLLWEIFTLGGNPYPSVPVEDLFN 6
Score = 36.6 bits (83), Expect = 0.030, Method: Compositional matrix adjust.
Identities = 33/119 (27%), Positives = 53/119 (44%), Gaps = 5/119 (4%)
Frame = -3
Query: 334 RDRMKLTDFNFLMVLGKGSFGKVMLSERKG-----TDELYAVKILKKDVVIQDDDVECTM 388
R+R+ L D LG+G+FG VM E G AVK+LK+D D ++ +
Sbjct: 845 RERLVLGD-----RLGEGAFGLVMKGEAMGIFKDNNSVTVAVKMLKEDAT--DREMMDLI 687
Query: 389 VEKRVLALPGKPPFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYA 447
E ++ + GK + L C LY ++E+ G+L ++ PH Y+
Sbjct: 686 REMEMMKVIGKHKNIINLLGCCTQRGALYVIVEFAPHGNLRDFLKS----HRPHGTSYS 522
>21433
Length = 590
Score = 60.1 bits (144), Expect = 3e-09, Method: Composition-based stats.
Identities = 35/96 (36%), Positives = 56/96 (58%)
Frame = +2
Query: 446 YAAEIAIGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTKTFCGTP 505
Y +++ L + + +I+RD+K +N++L +G +KIADFG TT CGT
Sbjct: 182 YIYQLSSALEYCHYRKVIHRDIKPENLLLGLKGDLKIADFGWSVHAPSSRRTT--MCGTL 355
Query: 506 DYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAPF 541
DY+ PE++ + + ++VD W+ GVL YE L G P
Sbjct: 356 DYLPPEMVEGKTHDENVDLWSLGVLCYEFLVGTPPL 463
>37602
Length = 804
Score = 59.7 bits (143), Expect = 4e-09, Method: Compositional matrix adjust.
Identities = 32/90 (35%), Positives = 47/90 (52%), Gaps = 2/90 (2%)
Frame = -1
Query: 414 DRLYFVMEYVNGGDL--MYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSKGIIYRDLKLDN 471
++L+ MEY GG + +YH+ G EP F E GL +L +G ++RD+K N
Sbjct: 300 EKLWIAMEYCGGGSMQDIYHV--TGPLTEPQIAFVCRETLKGLHYLHRRGKMHRDIKGAN 127
Query: 472 VMLDSEGHIKIADFGMCKENIWDGVTTKTF 501
++L EG +K+ADF N V K F
Sbjct: 126 ILLTEEGDVKLADFWRVSSNHSHNVQKKVF 37
>11185
Length = 473
Score = 59.3 bits (142), Expect = 6e-09, Method: Compositional matrix adjust.
Identities = 34/115 (29%), Positives = 54/115 (46%), Gaps = 22/115 (19%)
Frame = +1
Query: 446 YAAEIAIGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCK---ENI---------- 492
+ + GL ++ S GI++ DL+ V+LD+ G +K ADFG+ K EN+
Sbjct: 16 FGIHLVTGLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEA 195
Query: 493 ---WDGVTTKTF------CGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQ 538
W+ + + G+P Y+APE+ D WA G + YEM +G
Sbjct: 196 GDQWNIQSAEEMMKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSGS 360
>35187
Length = 593
Score = 58.5 bits (140), Expect = 8e-09, Method: Compositional matrix adjust.
Identities = 25/51 (49%), Positives = 32/51 (62%)
Frame = -3
Query: 36 NHKFTARFFKQPTFCSHCTDFIWGFGKQGFQCQVCCFVVHKRCHEFVTFSC 86
H FT + F +PT+C HCTD +WG G+ C+VC FVVH RC + V C
Sbjct: 318 GHFFTKKTFHKPTYCHHCTDILWGLIGVGYVCEVCNFVVHDRCMKTVVSPC 166
Score = 48.9 bits (115), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 24/61 (39%), Positives = 31/61 (50%)
Frame = -3
Query: 93 PASDDPRSKHKFKIHTYSSPTFCDHCGSLLYGLIHQGMKCDTCMMNVHKRCVMNVPSLCG 152
P D H F T+ PT+C HC +L+GLI G C+ C VH RC+ V S C
Sbjct: 342 PVPPDHGHGHFFTKKTFHKPTYCHHCTDILWGLIGVGYVCEVCNFVVHDRCMKTVVSPCS 163
Query: 153 T 153
+
Sbjct: 162 S 160
>01756
Length = 1858
Score = 58.2 bits (139), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 52/230 (22%), Positives = 102/230 (44%), Gaps = 19/230 (8%)
Frame = -3
Query: 345 LMVLGKGSFGKVMLSERKGTDELYAVKILKKDVVIQDDDVE----CTMVEKRVLALPGKP 400
L +G+G+FG+V + K T ++ A+K V+ D++ E + E ++L L
Sbjct: 1727 LAKIGQGTFGEVFKARCKKTKQVVAMK-----KVLMDNEKEGFPITALREIKILQLLNHE 1563
Query: 401 PFLTQLHSC---------FQTMDRLYFVMEYV--NGGDLMYHIQQVGRFKEPHAVFYAAE 449
+ + C +++M Y V E+ + L+ ++ V F P +
Sbjct: 1562 NVVDLIEICSTKATSANRYKSM--FYLVFEFCEHDLAGLLSNMSVV--FNLPEIKEVMKQ 1395
Query: 450 IAIGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCKE---NIWDGVTTKTFCGTPD 506
+ GL+++ I++RD+K N+++ +G +K+ADFG+ + N+ T
Sbjct: 1394 LMNGLYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLW 1215
Query: 507 YIAPE-IIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIME 555
Y PE ++ + Y ++D W G ++ EM +G E I +
Sbjct: 1214 YRPPELLLGDRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQNQLTLITQ 1065
>12672
Length = 773
Score = 58.2 bits (139), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 37/118 (31%), Positives = 61/118 (51%), Gaps = 4/118 (3%)
Frame = +3
Query: 451 AIGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFG-MCKENIWDGVTTK---TFCGTPD 506
A G+ +L G ++RD+K N++LDSE K+ DF + +G T + GT
Sbjct: 21 ASGIQYLNDNGHVHRDIKTANILLDSEYTAKVGDFATVVSAPSGEGKTVQNASVVIGTAA 200
Query: 507 YIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHNVAYPKSM 564
Y+APE I + K +D ++FGV+L E++ G + E+ S + NV P+ +
Sbjct: 201 YLAPEAIHFDVSTK-LDSYSFGVVLLEVITGLVAQDYSREERTLSSHIMENVEEPEEI 371
>29179
Length = 1113
Score = 57.8 bits (138), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 44/123 (35%), Positives = 66/123 (53%), Gaps = 4/123 (3%)
Frame = -3
Query: 148 PSLCGTDHTERRGRIYIQAHIDRDVLIVLVR--DAKNLVPMDPNGLSDPYVKLKLIPDPK 205
P + G D+ + GRI D L + +R A +L D G SDPYVK+ L+PD K
Sbjct: 568 PIVEGVDY--KLGRIQFGLMYDFQNLTLTLRIIRAVDLPAKDVTGTSDPYVKILLLPDKK 395
Query: 206 SESKQKTKTIKCSLNPEWNETFRFQLKESDK--DRRLSVEIWDWDLTSRNDFMGSLSFGI 263
K TK K +LNP WNE F F+ +K ++ L +++ D+D SR+D +G +
Sbjct: 394 --HKLLTKVKKRNLNPHWNECFLFEGWPHNKLLEKTLYLQVIDYDRFSRDDPIGETYLPL 221
Query: 264 SEL 266
+E+
Sbjct: 220 NEI 212
Score = 28.9 bits (63), Expect = 6.4, Method: Compositional matrix adjust.
Identities = 18/37 (48%), Positives = 21/37 (56%)
Frame = -1
Query: 164 IQAHIDRDVLIVLVRDAKNLVPMDPNGLSDPYVKLKL 200
I +I R L V+V AK L D G SDPYVK+ L
Sbjct: 120 ISPNIGR--LTVIVMKAKELKAKDITGSSDPYVKIWL 16
>17300
Length = 480
Score = 57.4 bits (137), Expect = 2e-08, Method: Composition-based stats.
Identities = 31/109 (28%), Positives = 62/109 (56%), Gaps = 5/109 (4%)
Frame = +1
Query: 450 IAIGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCKE---NIWDGVTTKTFCGTP- 505
I+ G+ L G ++RDL N++++ K+ADFG+ +E + +G T P
Sbjct: 1 ISSGMGXLADMGYVHRDLAARNILVNEILVCKVADFGLSREIESDTTEGAYTTKGGKIPV 180
Query: 506 DYIAPEIIAYQPYGKSVDWWAFGVLLYEMLA-GQAPFEGEDEDELFQSI 553
+ APE IAY+ + + D W+FGV+++E+++ G+ P+ ++ +++
Sbjct: 181 RWTAPEAIAYRKFTSASDVWSFGVVMWEVMSYGERPYWNWSNQDVIKAV 327
>01966
Length = 1735
Score = 48.5 bits (114), Expect(2) = 3e-08, Method: Compositional matrix adjust.
Identities = 33/106 (31%), Positives = 52/106 (49%), Gaps = 6/106 (5%)
Frame = -1
Query: 414 DRLYFVMEYVNGGDLMYHIQQVGRFKEPHAV------FYAAEIAIGLFFLQSKGIIYRDL 467
+RL+ V E+++ MY + +F E + Y +I G+ F + I++RDL
Sbjct: 1495 ERLFLVFEFLSMDLKMY----IDKFPEGVVLDRRLVKSYVFQIVTGINFCHQRRIVHRDL 1328
Query: 468 KLDNVMLDSEGHIKIADFGMCKENIWDGVTTKTFCGTPDYIAPEII 513
K N++++ G IKIADFGM + T Y APEI+
Sbjct: 1327 KPQNLLINHTGAIKIADFGMARTFALPVRAYTHEVVTLWYRAPEIL 1190
Score = 27.7 bits (60), Expect(2) = 3e-08, Method: Compositional matrix adjust.
Identities = 13/35 (37%), Positives = 20/35 (57%), Gaps = 1/35 (2%)
Frame = -3
Query: 518 YGKSVDWWAFGVLLYEMLAGQAPFEGEDE-DELFQ 551
Y VD W+ G + +ML F+G+ E D+LF+
Sbjct: 1175 YSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFK 1071
>11780
Length = 1713
Score = 50.1 bits (118), Expect(2) = 6e-08, Method: Compositional matrix adjust.
Identities = 37/151 (24%), Positives = 74/151 (49%), Gaps = 2/151 (1%)
Frame = +3
Query: 341 DFNFLMVLGKGSFGKVMLSERKGTDELYAVKILKKDVVIQDDDVECTMVEKRVLALPGKP 400
D +GKG FG V +G + A+K LK D E + +++ + +
Sbjct: 600 DLEIGEAIGKGDFGDVYKGMYRG--QPVAIKQLK-----DKDRGEQSFLQEASVMTSLRH 758
Query: 401 PFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGR--FKEPHAVFYAAEIAIGLFFLQ 458
L +L + ++ V E++ G+L+ +++ GR + + +A + + +L+
Sbjct: 759 DNLVRLIGVVLG-ETIFLVTEFMGKGNLVEYLRSRGRSVITKKDQINFATDTCAAMEYLE 935
Query: 459 SKGIIYRDLKLDNVMLDSEGHIKIADFGMCK 489
SK +++RDL NV++ +G K++DFG+ K
Sbjct: 936 SKRLVHRDLAARNVLVHDDGKAKVSDFGLAK 1028
Score = 25.0 bits (53), Expect(2) = 6e-08, Method: Compositional matrix adjust.
Identities = 15/63 (23%), Positives = 30/63 (47%), Gaps = 2/63 (3%)
Frame = +1
Query: 523 DWWAFGVLLYEMLA-GQAPFEGEDEDELFQSIME-HNVAYPKSMSKEAVAICKGLMTKHP 580
D W+FG+LL+E+ + G+ P+ ++ + + + P+ E +I K P
Sbjct: 1120 DMWSFGILLWEIYSFGRVPYPRIPLTDVVMHVERGYRMEAPEGCPPEIYSIMKQAWELDP 1299
Query: 581 GKR 583
+R
Sbjct: 1300 NER 1308
>19761
Length = 473
Score = 55.5 bits (132), Expect = 6e-08, Method: Compositional matrix adjust.
Identities = 35/150 (23%), Positives = 67/150 (44%), Gaps = 2/150 (1%)
Frame = -3
Query: 431 HIQQVGRFKEPHAVFYAAEIAIGLFFLQSKG--IIYRDLKLDNVMLDSEGHIKIADFGMC 488
H+ E V + + A L ++ + I++RDLK N+ + +G +++ D G+
Sbjct: 453 HLGFTAGLPERLIVCWLMQTASALNYMHTHTPVILHRDLKPQNIYVTEKGDVRLGDLGLA 274
Query: 489 KENIWDGVTTKTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDE 548
++ + GT Y++PEI++ QPY D W+ G + Y++ + E
Sbjct: 273 RKLTGPADFATSQVGTIMYLSPEILSQQPYNSKSDIWSLGCVFYDITGKKGSDEMGVMFL 94
Query: 549 LFQSIMEHNVAYPKSMSKEAVAICKGLMTK 578
L Q + + P S+E ++TK
Sbjct: 93 LVQVMGGRKLPLPDHYSQEFRDTISRMLTK 4
>07291
Length = 833
Score = 55.5 bits (132), Expect = 7e-08, Method: Compositional matrix adjust.
Identities = 35/143 (24%), Positives = 66/143 (46%), Gaps = 5/143 (3%)
Frame = +1
Query: 446 YAAEIAIGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTKTFCGTP 505
+ +IA G+ +LQ +++R+L N ++ +G ++++D+G+ T
Sbjct: 64 FGRQIADGMAYLQEVKVVHRNLAARNCIVTEDGRLQLSDYGVTGSLFPQSYYTADDSPAR 243
Query: 506 D---YIAPEIIAYQPYGKSVDWWAFGVLLYEMLA-GQAPFEGEDEDELFQSIME-HNVAY 560
D ++APE I + D WAFGV+L+E+L G P+ + L + E H +
Sbjct: 244 DLVKWMAPETIDNFHFSSKSDVWAFGVVLWELLTRGITPYPDVENSSLLPYLKEGHRMKK 423
Query: 561 PKSMSKEAVAICKGLMTKHPGKR 583
PK + + + P +R
Sbjct: 424 PKQSPEPVYEMMTACWNESPEQR 492
>00715
Length = 1788
Score = 55.1 bits (131), Expect = 8e-08, Method: Compositional matrix adjust.
Identities = 44/157 (28%), Positives = 68/157 (43%), Gaps = 27/157 (17%)
Frame = +1
Query: 414 DRLYFVMEYVNGGDLMY----HIQQVGRFKEPHAVFYAAEIAIGLFFLQSKGIIYRDLKL 469
D + MEYV +L H Q + + A ++A GL +L S I++ DLK
Sbjct: 154 DGAWLAMEYVGPLNLQTILNDHQQDI---DSSMRLSLALQMARGLHYLHSINIVHLDLKP 324
Query: 470 DNVMLDSEGHIKIADFGMCKENIWDGVTT----------------------KTFCGTPDY 507
N +L + ++IADFG C + G+ GT Y
Sbjct: 325 ANCLLTRDLKLRIADFGCCHQLTPTGLDMGEREGGMAGNELELTPVQGAWKNELAGTLAY 504
Query: 508 IAPEII-AYQPYGKSVDWWAFGVLLYEMLAGQAPFEG 543
APE++ QP +S D ++ G+ L++M Q P+EG
Sbjct: 505 RAPELLKGLQPSVRS-DVYSLGITLWQMCTRQGPYEG 612
>33586
Length = 551
Score = 47.0 bits (110), Expect(2) = 9e-08, Method: Composition-based stats.
Identities = 21/53 (39%), Positives = 31/53 (58%), Gaps = 1/53 (1%)
Frame = +2
Query: 399 KPP-FLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEI 450
+PP F+ LH FQT +LY ++E++ GGDL + + F E FY AE+
Sbjct: 392 QPPLFIVHLHYAFQTEGKLYLILEFLRGGDLFTRLSKEVMFTEEDVKFYLAEL 550
Score = 27.7 bits (60), Expect(2) = 9e-08, Method: Compositional matrix adjust.
Identities = 12/22 (54%), Positives = 15/22 (68%)
Frame = +1
Query: 340 TDFNFLMVLGKGSFGKVMLSER 361
+ F L VLG+GSFG+V S R
Sbjct: 214 SQFELLKVLGQGSFGRVFXSGR 279
>29590
Length = 320
Score = 54.7 bits (130), Expect = 1e-07, Method: Composition-based stats.
Identities = 22/49 (44%), Positives = 29/49 (59%)
Frame = +3
Query: 495 GVTTKTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEG 543
G + GTPDY+APE++ Y+P D W+ GVL Y ML +PF G
Sbjct: 36 GEDIRDIIGTPDYVAPEVLDYEPLSIQTDMWSLGVLSYVMLTACSPFVG 182
>31935
Length = 554
Score = 53.9 bits (128), Expect = 2e-07, Method: Composition-based stats.
Identities = 38/130 (29%), Positives = 63/130 (48%), Gaps = 6/130 (4%)
Frame = -3
Query: 154 DHTERRGRIYIQAHIDRDVLIVLVRDAKNLVPMDPNGLSDPYVKLKLIPDPKSESKQKTK 213
+H R ++ I R L V + N+ DP+ + DPYVKL L+P ESK+KT
Sbjct: 549 EHGLGRIQLTITYSAQRQKLDVTIHKIMNIPLRDPSSIPDPYVKLHLLPGRSKESKRKTS 370
Query: 214 TIKCSLNPEWNETFRFQLKESD-KDRRLSVEIWDWD--LTSRNDFMGSLSFGISELQ--- 267
IK + NP ++ +F + + S+ + L V + L+S + +G L + + +
Sbjct: 369 IIKDNCNPVYDASFEYLISISELRHTELEVTVCTQKGFLSSGSPIIGMLKIPLDDSEITT 190
Query: 268 KASVDGWFKL 277
A + WF L
Sbjct: 189 PAGLKSWFDL 160
>12786
Length = 460
Score = 53.5 bits (127), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 36/120 (30%), Positives = 55/120 (45%), Gaps = 22/120 (18%)
Frame = -3
Query: 445 FYAAEIAIGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWD--GVTTKTFC 502
FY E+ + L ++G+I+ DLK N ML + G++K+ DFG+ D V +
Sbjct: 398 FYWREMLRAVKALHNEGVIHSDLKPANFMLVA-GNLKLIDFGIANTLQQDKTSVLKDSRV 222
Query: 503 GTPDYIAPEIIAYQ--------------------PYGKSVDWWAFGVLLYEMLAGQAPFE 542
GTP Y++PE I G D W+ G +LY M+ G+ PF+
Sbjct: 221 GTPSYMSPEAIMAACDDSADDSMEEDGHRTKPKYKVGVRSDVWSLGCILYNMVYGRTPFQ 42
>03508
Length = 1463
Score = 53.5 bits (127), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 37/126 (29%), Positives = 60/126 (47%), Gaps = 2/126 (1%)
Frame = +1
Query: 418 FVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSKGIIYRDLKLDNVMLDSE 477
+ E+VN D Q F + FY E+ L F S GI++RD+K NVM+D E
Sbjct: 811 LIFEHVNNTDFK---QLYQTFTDYDIRFYLYELMKALDFCHSMGIMHRDVKPHNVMIDHE 981
Query: 478 G-HIKIADFGMCKENIWDGVTTKTFCGTPDYIAPEIIA-YQPYGKSVDWWAFGVLLYEML 535
+++ D+G+ E G+ + + PE++ YQ Y S+D W+ G + M+
Sbjct: 982 NKKLRLIDWGLA-EFYHPGMEYNVRVASRYFKGPELLLDYQMYDYSLDMWSLGCMFASMI 1158
Query: 536 AGQAPF 541
+ P
Sbjct: 1159FRKEPL 1176
>30339
Length = 384
Score = 52.4 bits (124), Expect = 6e-07, Method: Composition-based stats.
Identities = 24/35 (68%), Positives = 27/35 (77%)
Frame = -2
Query: 329 DNNGNRDRMKLTDFNFLMVLGKGSFGKVMLSERKG 363
D + DR L DFNF+ VLGKGSFGKVML+ERKG
Sbjct: 107 DRGRSSDRFHLHDFNFIKVLGKGSFGKVMLAERKG 3
>19361
Length = 685
Score = 51.6 bits (122), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 21/72 (29%), Positives = 36/72 (50%), Gaps = 9/72 (12%)
Frame = -1
Query: 89 ADKGPASDDPRSK---------HKFKIHTYSSPTFCDHCGSLLYGLIHQGMKCDTCMMNV 139
+ P D+P H FK+ ++ +C+ C + ++GLI QG+KC C +
Sbjct: 382 VNSTPEEDEPEQSIDWTQYEKPHVFKVQNFNGLNWCELCANFMWGLIAQGVKCQDCGVQT 203
Query: 140 HKRCVMNVPSLC 151
HK+C +P+ C
Sbjct: 202 HKKCSERMPNEC 167
Score = 45.8 bits (107), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 19/52 (36%), Positives = 26/52 (50%)
Frame = -1
Query: 35 KNHKFTARFFKQPTFCSHCTDFIWGFGKQGFQCQVCCFVVHKRCHEFVTFSC 86
K H F + F +C C +F+WG QG +CQ C HK+C E + C
Sbjct: 322 KPHVFKVQNFNGLNWCELCANFMWGLIAQGVKCQDCGVQTHKKCSERMPNEC 167
>11353
Length = 454
Score = 50.8 bits (120), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 21/50 (42%), Positives = 29/50 (58%)
Frame = +1
Query: 102 HKFKIHTYSSPTFCDHCGSLLYGLIHQGMKCDTCMMNVHKRCVMNVPSLC 151
H+F+ +TY++PT+CD C LL+G G C C N H +C VP C
Sbjct: 142 HRFEKYTYTTPTYCDFCQQLLWGFSKTGTHCVDCGYNCHDKCQPLVPKTC 291
Score = 45.1 bits (105), Expect = 9e-05, Method: Compositional matrix adjust.
Identities = 17/50 (34%), Positives = 24/50 (48%)
Frame = +1
Query: 37 HKFTARFFKQPTFCSHCTDFIWGFGKQGFQCQVCCFVVHKRCHEFVTFSC 86
H+F + PT+C C +WGF K G C C + H +C V +C
Sbjct: 142 HRFEKYTYTTPTYCDFCQQLLWGFSKTGTHCVDCGYNCHDKCQPLVPKTC 291
>30040
Length = 652
Score = 50.1 bits (118), Expect = 3e-06, Method: Composition-based stats.
Identities = 28/91 (30%), Positives = 46/91 (50%), Gaps = 1/91 (1%)
Frame = -3
Query: 173 LIVLVRDAKNLVPMDPNGLSDPYVKLKLIPDPKSESKQKTKTIKCSLNPEWNETFRFQL- 231
L V++ AK+L + +DP+V++ L+ + K ++KT + S+NP WNE F +
Sbjct: 611 LTVVLMKAKDLKMSTSHPSADPFVRVSLLVEGKKVKRKKTSVRRASINPVWNEALAFNVP 432
Query: 232 KESDKDRRLSVEIWDWDLTSRNDFMGSLSFG 262
E L V + D DL D +G+ G
Sbjct: 431 AEVLPKVTLEVSVLDHDLIGHGDVLGTCVLG 339
>22804
Length = 967
Score = 49.7 bits (117), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 21/51 (41%), Positives = 29/51 (56%)
Frame = -3
Query: 102 HKFKIHTYSSPTFCDHCGSLLYGLIHQGMKCDTCMMNVHKRCVMNVPSLCG 152
H+F+ +TY++PT+CD C LL+G G C C N H +C VP C
Sbjct: 830 HRFEKYTYTTPTYCDFCQQLLWGFSKTGTHCVDCGYNCHDKCQPLVPKTCS 678
Score = 43.5 bits (101), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 17/50 (34%), Positives = 24/50 (48%)
Frame = -3
Query: 37 HKFTARFFKQPTFCSHCTDFIWGFGKQGFQCQVCCFVVHKRCHEFVTFSC 86
H+F + PT+C C +WGF K G C C + H +C V +C
Sbjct: 830 HRFEKYTYTTPTYCDFCQQLLWGFSKTGTHCVDCGYNCHDKCQPLVPKTC 681
>01718
Length = 959
Score = 48.5 bits (114), Expect = 9e-06, Method: Compositional matrix adjust.
Identities = 35/129 (27%), Positives = 67/129 (51%), Gaps = 7/129 (5%)
Frame = +3
Query: 415 RLYFVMEYVNGGDLMYHIQQVGR-FKEPHAVFYAAEIAIGLFFLQSKGIIYRDLKLDNVM 473
+L+ + EY+ G+L +++ + +A GL +L S I+RDL N++
Sbjct: 354 QLHALTEYIPSGNLEQLLEKKDEELPWTQRIQLTLGLARGLDYLHSTRFIHRDLTSKNIL 533
Query: 474 L---DSEG-HIKIADFGMCKENIWDGVTTKTF--CGTPDYIAPEIIAYQPYGKSVDWWAF 527
+ D+ G H IADFG+ + I D + + G+P ++APE++ Y + D ++
Sbjct: 534 IRREDNHGYHAVIADFGLATK-IPDPLDKEKLPTVGSPYWMAPEVLNGHFYNERADLFSV 710
Query: 528 GVLLYEMLA 536
G+++ E+ A
Sbjct: 711 GIIMCEITA 737
>26525
Length = 455
Score = 48.1 bits (113), Expect = 1e-05, Method: Composition-based stats.
Identities = 24/49 (48%), Positives = 36/49 (73%), Gaps = 1/49 (2%)
Frame = +1
Query: 182 NLVPMDPN-GLSDPYVKLKLIPDPKSESKQKTKTIKCSLNPEWNETFRF 229
+L P DP+ G DPYVKL+L+P+ K K KT+ ++ +LNP+++ETF F
Sbjct: 1 DLPPRDPSLGGCDPYVKLQLLPEKKH--KCKTRVVRKTLNPKYDETFTF 141
Score = 30.0 bits (66), Expect = 3.5, Method: Composition-based stats.
Identities = 12/19 (63%), Positives = 16/19 (84%)
Frame = +2
Query: 180 AKNLVPMDPNGLSDPYVKL 198
++NL MD +GLSDPYVK+
Sbjct: 398 SRNLPKMDISGLSDPYVKI 454
>17975
Length = 449
Score = 48.1 bits (113), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 40/138 (28%), Positives = 70/138 (50%), Gaps = 4/138 (2%)
Frame = +3
Query: 353 FGKVMLSERKGTDELYAVKILKKDVVIQDDDVECTMV--EKRVLALPGKPPFLTQLHSCF 410
F V L+ T E AVK++ K + D+V + + E R + L P + +L+
Sbjct: 6 FAVVKLARHVFTGEKVAVKVIDKT---KLDEVSRSHLFQEVRCMKLVQHPN-VVRLYEVI 173
Query: 411 QTMDRLYFVMEYVNGGDLM-YHIQQVGRFKEPHAVFYAAEIAIGLFFLQSKGIIYRDLKL 469
T +LY ++E +GGD+ Y ++ G +E A Y +I + + +++RDLK
Sbjct: 174 DTQTKLYLILELGDGGDMYDYIMRHSGGLEEKLAKRYFRQIVEAISYCHKLHVVHRDLKP 353
Query: 470 DNVM-LDSEGHIKIADFG 486
+NV+ + G +K+ DFG
Sbjct: 354 ENVVFFEKPGLVKLTDFG 407
>20640
Length = 1492
Score = 46.6 bits (109), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 34/128 (26%), Positives = 58/128 (45%), Gaps = 4/128 (3%)
Frame = +1
Query: 460 KGIIYRDLKLDNVMLDSEGHIKIADFGMCKE-NIWDGVTTKTFCGTPDYIAP-EIIAYQP 517
+G ++RDL N ++ + +KI+DFG+ + + D P P E I Y
Sbjct: 1 RGYVHRDLATRNCLVGHDLVVKISDFGLARSVHSVDYYRGSEHDAIPIRWMPLEAILYNK 180
Query: 518 YGKSVDWWAFGVLLYEMLA-GQAPFEGEDEDELFQSIMEHNV-AYPKSMSKEAVAICKGL 575
+ D W+FGV+L+E+ A P+ G +E+ + + E V A P+ + K
Sbjct: 181 FSTQSDVWSFGVVLWEIFAFALQPYYGLTHEEVVRFVKEGKVLACPERTPPPMYELMKQC 360
Query: 576 MTKHPGKR 583
+ P R
Sbjct: 361 WHRRPATR 384
>19301
Length = 712
Score = 46.6 bits (109), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 27/70 (38%), Positives = 41/70 (58%), Gaps = 1/70 (1%)
Frame = +2
Query: 418 FVMEYVNGGDLMYHIQQVGRFKEPHAVF-YAAEIAIGLFFLQSKGIIYRDLKLDNVMLDS 476
+MEY G L Y + + G+ P V ++ +IA G+ +L S II+RDLK NV++
Sbjct: 500 IIMEYCPYGQL-YEVLRDGKEIPPALVLDWSKQIASGMNYLHSHKIIHRDLKSPNVLVAK 676
Query: 477 EGHIKIADFG 486
+KI+DFG
Sbjct: 677 NDVVKISDFG 706
>20152
Length = 445
Score = 46.2 bits (108), Expect = 4e-05, Method: Composition-based stats.
Identities = 22/75 (29%), Positives = 40/75 (53%), Gaps = 1/75 (1%)
Frame = +1
Query: 510 PEIIAYQPY-GKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHNVAYPKSMSKEA 568
PEI+ Y +VD W+ GV+LY ++ G+APF+ ++ E IM+ P +S +
Sbjct: 1 PEILLGDSYDAPAVDVWSLGVILYMLVVGEAPFQEANDSETLTMIMDCRYQIPPHISHKC 180
Query: 569 VAICKGLMTKHPGKR 583
+ + ++ + P R
Sbjct: 181 QDLIEKMLQREPVDR 225
>04138
Length = 800
Score = 46.2 bits (108), Expect = 4e-05, Method: Compositional matrix adjust.
Identities = 26/106 (24%), Positives = 50/106 (47%), Gaps = 4/106 (3%)
Frame = +1
Query: 454 LFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCKE---NIWDGVTTKTFCGTPDYIAP 510
L+++ I++RD+K N+++ +G +K+ADFG+ + N+ T Y P
Sbjct: 52 LYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRPP 231
Query: 511 E-IIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIME 555
E ++ + Y ++D W G ++ EM +G E I +
Sbjct: 232 ELLLGDRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQNQLTLITQ 369
>17932
Length = 597
Score = 33.5 bits (75), Expect(2) = 6e-05, Method: Composition-based stats.
Identities = 12/22 (54%), Positives = 14/22 (63%)
Frame = -2
Query: 524 WWAFGVLLYEMLAGQAPFEGED 545
WW+ GV YEML G PF +D
Sbjct: 596 WWSLGVCAYEMLFGCTPFTDDD 531
Score = 31.6 bits (70), Expect(2) = 6e-05, Method: Composition-based stats.
Identities = 33/122 (27%), Positives = 52/122 (42%), Gaps = 4/122 (3%)
Frame = -3
Query: 552 SIMEHNVAYPKSMSKEAVAICKGLMTKHPGK-RLGCGPEGERDIKEHAFFRYIDWEKLER 610
+I + V S+SKEA + L++ GK RLG PE +++H FF+ +DW +
Sbjct: 496 TIRQTQVPPHSSVSKEARDLISQLLSD--GKSRLGW-PE----LQQHPFFKTVDWANI-- 344
Query: 611 KEIQPPYKPKACG-RNAENFDRFFTRHPPVLTPPDQEVIRNIDQSEFEG--FSFVNSEFL 667
+ PPY P + +FD P P+ + +F G FV +
Sbjct: 343 RNAMPPYVPSISSLDDTSHFDEVEKARP----APNIDSFHQPSSRDFTGRHLPFVGFTYF 176
Query: 668 KP 669
P
Sbjct: 175 HP 170
>17591
Length = 474
Score = 45.4 bits (106), Expect = 8e-05, Method: Compositional matrix adjust.
Identities = 24/57 (42%), Positives = 35/57 (61%), Gaps = 1/57 (1%)
Frame = +3
Query: 582 KRLGCGPEGERDIKEHAFFRYIDWEKLERKEIQPPYKPKACGR-NAENFDRFFTRHP 637
+RLG + E +I+E AFF I+W+ L K++QPPY P G+ + +FD F R P
Sbjct: 153 ERLGAKRDFE-EIQEKAFFADINWDDLYNKKVQPPYNPNVSGQLDLRHFDPEFVREP 320
>07591
Length = 796
Score = 45.4 bits (106), Expect = 8e-05, Method: Compositional matrix adjust.
Identities = 27/101 (26%), Positives = 50/101 (49%), Gaps = 3/101 (2%)
Frame = +2
Query: 174 IVLVRDAKNLVPMDPNGLSDPYVK-LKLIPDPKSESKQKTKTIKCSLNPEWN--ETFRFQ 230
+ + AK L D G SDPY++ L+ D + +T+ +K +LNP W E
Sbjct: 461 VAMTFHAKKLDKKDFLGKSDPYLEVLRATSDGSWQMVHRTEVVKNNLNPSWRPFELSMQT 640
Query: 231 LKESDKDRRLSVEIWDWDLTSRNDFMGSLSFGISELQKASV 271
L + + + +++DWD +D++G + + ++ KAS
Sbjct: 641 LCGGNHQQNIKFDVYDWDSDGSHDYIGGFTTTLQDMLKASA 763
>07833
Length = 1504
Score = 45.1 bits (105), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 51/199 (25%), Positives = 86/199 (43%), Gaps = 8/199 (4%)
Frame = -3
Query: 393 VLALPGKPPFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAI 452
VLA +PP L L S F LY + +G ++ Q RF A +IA
Sbjct: 1424 VLACCNQPPNLV-LISQFMPFGSLYNTLHGESG--IVVDQNQSLRF--------AMDIAR 1278
Query: 453 GLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWD---GVTTKTFCGTPDYIA 509
G+ FL S + + N +L S+ H+ I + + N+ D K +P ++A
Sbjct: 1277 GMEFLHSM-----EPTIPNFLLTSK-HVMIDEDLTARINMADYCFSFHEKGKVYSPAWMA 1116
Query: 510 PEIIAYQP---YGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHN--VAYPKSM 564
PE + +P ++ D W+F +L++E+ + PF E+ + ++ P +
Sbjct: 1115 PEALQRRPDDINTRAADMWSFAILMWELETREVPFAELSSMEVGMKVALEGLRISIPPGI 936
Query: 565 SKEAVAICKGLMTKHPGKR 583
S + K M + PGKR
Sbjct: 935 SLHMSRLIKICMNEEPGKR 879
>30743
Length = 569
Score = 44.3 bits (103), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 18/39 (46%), Positives = 22/39 (56%)
Frame = +2
Query: 106 IHTYSSPTFCDHCGSLLYGLIHQGMKCDTCMMNVHKRCV 144
+HT+ P CD CG LL G+ QG C M VHK C+
Sbjct: 338 MHTFEKPKECDVCGKLLRGIFFQGYLCQDNQMAVHKECI 454
Score = 28.9 bits (63), Expect = 6.7, Method: Compositional matrix adjust.
Identities = 13/35 (37%), Positives = 17/35 (48%)
Frame = +2
Query: 44 FKQPTFCSHCTDFIWGFGKQGFQCQVCCFVVHKRC 78
F++P C C + G QG+ CQ VHK C
Sbjct: 347 FEKPKECDVCGKLLRGIFFQGYLCQDNQMAVHKEC 451
>27274
Length = 396
Score = 44.3 bits (103), Expect = 2e-04, Method: Composition-based stats.
Identities = 27/94 (28%), Positives = 49/94 (52%), Gaps = 5/94 (5%)
Frame = -1
Query: 511 EIIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGE-DEDELFQSIMEHNVAYPKSMSKEAV 569
E++ Q +G +VD W+ G+LL+E+L+G PFE E ++ +++M Y + + +
Sbjct: 375 ELLRGQQHGPTVDMWSLGILLHELLSGHVPFEPERGSRQMARNMM---AVYAQIIRGSSR 205
Query: 570 AICKGLMTKHPG----KRLGCGPEGERDIKEHAF 599
+C GL G +RL + +R + AF
Sbjct: 204 DVCDGLALSTHGADFLRRLVQLEDTKRLTSQQAF 103
>16708
Length = 1397
Score = 43.5 bits (101), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 45/160 (28%), Positives = 67/160 (41%), Gaps = 14/160 (8%)
Frame = -1
Query: 344 FLMVLGKGSFGKVMLSERKGTDELYAVKILKKDVVIQD--DDVECT-----------MVE 390
L VLGKG FGKV + T E A LK ++ D+VE M
Sbjct: 1391 ILQVLGKGVFGKVYEARLLSTHEKAA---LKTSILCHHSLDEVEALGRIEGGFYLAQMFG 1221
Query: 391 KRVLALPGKPPFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVF-YAAE 449
V LP P LH F M L V + ++ R+ P V A +
Sbjct: 1220 AWVTCLP-FPKMNILLH--FYEMGPLCNVYAHYKNKEMPI------RWSNPAMVCCIAGQ 1068
Query: 450 IAIGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCK 489
L + G+++ D+K DNV++D+ G+ K+ D+G+ +
Sbjct: 1067 XVCALEHIHELGVVHMDVKADNVLVDAHGNCKLTDYGIAQ 948
>03942
Length = 912
Score = 40.8 bits (94), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 24/63 (38%), Positives = 33/63 (52%), Gaps = 3/63 (4%)
Frame = +2
Query: 549 LFQSIMEHNVAYPKSMSKEAVAICKGLMTKHPGKRLGCGPE--GERDIKEHAFF-RYIDW 605
L+ ++ + AY M ++ MTK+P KRLGC E+ I HAFF + IDW
Sbjct: 29 LYMQVLCNEYAYLVYMFSMSLFCIFQFMTKNPAKRLGCVTSQGAEKAIFIHAFFHQKIDW 208
Query: 606 EKL 608
E L
Sbjct: 209 EAL 217
>36305
Length = 586
Score = 40.8 bits (94), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 26/77 (33%), Positives = 39/77 (50%)
Frame = -1
Query: 190 GLSDPYVKLKLIPDPKSESKQKTKTIKCSLNPEWNETFRFQLKESDKDRRLSVEIWDWDL 249
G SDPY + + KTK I ++ P WNE F F + E D + L + I D D
Sbjct: 583 GKSDPYTVVTV-----GAQTFKTKVIDDTVEPRWNEVFEFVIDERDG-QILKLNISDKDP 422
Query: 250 TSRNDFMGSLSFGISEL 266
+++D +GS + IS +
Sbjct: 421 GNKDDPLGSTTMDISTI 371
Score = 31.6 bits (70), Expect = 1.1, Method: Composition-based stats.
Identities = 19/62 (30%), Positives = 33/62 (53%)
Frame = -3
Query: 168 IDRDVLIVLVRDAKNLVPMDPNGLSDPYVKLKLIPDPKSESKQKTKTIKCSLNPEWNETF 227
++ D + L RD K+L ++P+ PYV L+L +++Q++ + P W E F
Sbjct: 194 VNLDSALDLPRDKKSL--LEPS----PYVTLRL-----GQTEQESGIRNATTEPRWEENF 48
Query: 228 RF 229
RF
Sbjct: 47 RF 42
>18996
Length = 491
Score = 40.0 bits (92), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 24/83 (28%), Positives = 45/83 (54%), Gaps = 5/83 (6%)
Frame = +2
Query: 463 IYRDLKLDNVMLDSEGHIKIADFGMCK----ENIWDGVTTKTFCGTPDYIAPEIIAYQPY 518
I+RDL N+++D +KI+DFG+ + + + G++ + + +PE I +
Sbjct: 2 IHRDLAARNILVD-RSCVKISDFGLAQFANADGYYYGISQRDI--PIKWYSPEAIETCKF 172
Query: 519 GKSVDWWAFGVLLYEMLA-GQAP 540
D W++GV L+EM + G+ P
Sbjct: 173 SSYSDVWSYGVTLFEMFSRGEIP 241
>07836
Length = 1478
Score = 40.0 bits (92), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 36/138 (26%), Positives = 66/138 (47%), Gaps = 18/138 (13%)
Frame = -1
Query: 415 RLYFVMEYVNGGDLM-YHIQQVGRFKEPHAVFYAA-----EIAIGLFFLQSK-GIIYRDL 467
+L+ + +Y G L Y + +V E A+ ++A + I +F + K I +RD+
Sbjct: 1331 QLFLITDYHENGSLHDYLLSRVLDSSEMLALAHSAICGLAHLHIEIFGTRGKPAIAHRDI 1152
Query: 468 KLDNVMLDSEGHIKIADFGMCKENIWDG----VTTKTFCGTPDYIAPEIIA-------YQ 516
K N+++ G IAD G+ I + V GT Y+APE++ +
Sbjct: 1151 KSKNILVKKNGTCCIADLGLAVRYISESNEVDVAPNPRQGTKRYMAPEVLEMLLNVKNFD 972
Query: 517 PYGKSVDWWAFGVLLYEM 534
+ K D +AFG++++E+
Sbjct: 971 AF-KQADMYAFGLVMWEI 921
>02638
Length = 1490
Score = 38.1 bits (87), Expect = 0.011, Method: Compositional matrix adjust.
Identities = 14/43 (32%), Positives = 26/43 (60%)
Frame = +1
Query: 503 GTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGED 545
GT ++APE++ + YG++ D W+ G ++ EM + P+ D
Sbjct: 22 GTIAFMAPEVLRGESYGRACDVWSVGCVMIEMCTCRPPWNSHD 150
>14477
Length = 493
Score = 36.6 bits (83), Expect = 0.030, Method: Composition-based stats.
Identities = 15/41 (36%), Positives = 27/41 (65%)
Frame = -1
Query: 449 EIAIGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCK 489
+++ G+ +L++ ++RDL N++L E KI+DFGM K
Sbjct: 166 QVSQGMEYLEANKFVHRDLAARNILLCDEHFAKISDFGMSK 44
>12442
Length = 468
Score = 36.6 bits (83), Expect = 0.034, Method: Composition-based stats.
Identities = 20/37 (54%), Positives = 23/37 (62%), Gaps = 3/37 (8%)
Frame = +3
Query: 575 LMTKHPGKRLGC--GPEGERDIKEHAFF-RYIDWEKL 608
MTK+P KRLGC E+ I HAFF + IDWE L
Sbjct: 105 FMTKNPAKRLGCVTSQGAEKAIFIHAFFHQKIDWEAL 215
>11404
Length = 563
Score = 36.2 bits (82), Expect = 0.043, Method: Compositional matrix adjust.
Identities = 33/134 (24%), Positives = 62/134 (46%), Gaps = 6/134 (4%)
Frame = +1
Query: 347 VLGKGSFGKVMLSERKGTDELYAVKILK-KDVVIQDDDVECTMVEKRVLALPGKPPFLTQ 405
++GKGSFG+V+ + +E A+KI+K K + +E ++E ++ +
Sbjct: 160 LIGKGSFGQVVKAYDHTDNEQVAIKIIKNKKPFLNQAQIEVKLLEMMNRHDTDNKYYIVR 339
Query: 406 LHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVF---YAAEIAIGLFFLQS--K 460
L F L V E ++ +Y + + F+ +A ++ L FL +
Sbjct: 340 LKRHFMFRSHLCLVFELLSYN--LYDLLRNTNFRGVSLNLTRKFAQQLCTALLFLATPEM 513
Query: 461 GIIYRDLKLDNVML 474
II+ DLK +N++L
Sbjct: 514 SIIHCDLKPENILL 555
>18401
Length = 463
Score = 35.8 bits (81), Expect = 0.064, Method: Compositional matrix adjust.
Identities = 20/70 (28%), Positives = 34/70 (48%), Gaps = 1/70 (1%)
Frame = -3
Query: 500 TFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHNV- 558
T T Y APE+I + D W+ G +++E+ G F+ D E ++ME +
Sbjct: 455 TIVSTRHYRAPEVILELGWSHPCDVWSVGCIMFELYTGYTLFQTHDNKEHL-AMMERILG 279
Query: 559 AYPKSMSKEA 568
+ P M+K+
Sbjct: 278 SLPYRMAKKT 249
>31120
Length = 439
Score = 34.7 bits (78), Expect = 0.14, Method: Composition-based stats.
Identities = 15/42 (35%), Positives = 26/42 (61%), Gaps = 1/42 (2%)
Frame = +1
Query: 511 EIIAYQPYG-KSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQ 551
E++ PY K D W+ GV+L+ ML G+ PF+ + ++L +
Sbjct: 1 EVVCGVPYDPKMADAWSLGVILFIMLNGKMPFDDSNLNKLLE 126
>22005
Length = 873
Score = 34.3 bits (77), Expect = 0.15, Method: Compositional matrix adjust.
Identities = 26/106 (24%), Positives = 46/106 (43%), Gaps = 6/106 (5%)
Frame = +1
Query: 436 GRFKEPHAVFYAAEIAIGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDG 495
G ++ + +I+ G+ +L K ++RDL V I+DFG+ +
Sbjct: 427 GMLXTKDQLYISQQISAGMAYLAQKDYVHRDLATRTVXS-RTT*S*ISDFGLARSV---- 591
Query: 496 VTTKTFCGTPDYIAP------EIIAYQPYGKSVDWWAFGVLLYEML 535
+ + G+ P E I Y + D W+FGV+L+E+L
Sbjct: 592 HSVDYYRGSEQDAIPIRWMPLEAILYSKFSTQSDVWSFGVVLWEIL 729
>17253
Length = 483
Score = 33.5 bits (75), Expect = 0.29, Method: Composition-based stats.
Identities = 24/109 (22%), Positives = 49/109 (44%), Gaps = 15/109 (13%)
Frame = -1
Query: 396 LPGKPPFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVF---------- 445
LP P ++ + C + D +ME+ GDL+ ++ + + VF
Sbjct: 378 LPRHPNVVSFMGCCTMS-DPALILMEFCCHGDLLSFLR---KRRPDRTVFLTSTANDLTA 211
Query: 446 -----YAAEIAIGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCK 489
+A +A G+ + + I++RD+ NV++ K++DFG+ +
Sbjct: 210 RDFFSFALHVARGMAHVANNKIVHRDVAARNVLISERNVCKVSDFGLSR 64
>13896
Length = 827
Score = 33.1 bits (74), Expect = 0.37, Method: Compositional matrix adjust.
Identities = 28/103 (27%), Positives = 49/103 (47%), Gaps = 2/103 (1%)
Frame = +2
Query: 177 VRDAKNLVPMDPNGLSDPYVKLKLIPDPKSESKQKTKTIKCSLNPEWNETFRFQLKESDK 236
V A+NL+ +G +D YV ++L + K +T TI+ + NPEW E +
Sbjct: 170 VLRARNLISKGKSGNNDVYVTIQL-----GKEKYQTSTIRNAHNPEWFEECDLPIPHLHS 334
Query: 237 DRRLSVEIWDWDLTSRNDFMGSLSFGISE--LQKASVDGWFKL 277
+ + V ++ + S +DF+G S + E L+ + W L
Sbjct: 335 E--IEVSVYHXGVLS-DDFLGYTSLPLWEQRLEDTTKTQWISL 454
>17516
Length = 453
Score = 33.1 bits (74), Expect = 0.39, Method: Composition-based stats.
Identities = 14/40 (35%), Positives = 24/40 (60%), Gaps = 1/40 (2%)
Frame = -3
Query: 500 TFCGTPDYIAPEIIAYQ-PYGKSVDWWAFGVLLYEMLAGQ 538
T GTP Y+APE++ + Y D ++ ++L+E+ GQ
Sbjct: 442 TLAGTPVYMAPEVLLQKGQYDMKADVYSLAIILWELWYGQ 323
>26009
Length = 886
Score = 32.7 bits (73), Expect = 0.43, Method: Compositional matrix adjust.
Identities = 41/167 (24%), Positives = 63/167 (37%), Gaps = 24/167 (14%)
Frame = +2
Query: 290 VPPEGSEANEELRQKFERAKISQGTKVPEEKTTNTVSKFDNNGNRDRMK-------LTDF 342
+PPE A+ +++ ER Q EE + TV ++G R K T
Sbjct: 212 LPPEVPPADLTVKKCDERDVGGQREVAVEESSATTVVSNQDDGGRGESKEDRSPRNSTSD 391
Query: 343 NFLMV-----------LGKGSFGKVMLSERKGTDELYAVKILKKDVVIQDDDVECTMVE- 390
N L + LG+G++GKV+L+ + T A+K+L K CT +
Sbjct: 392 NLLTLSLREHYDVCKELGRGTYGKVVLARCRHTGTQVALKLLPK---------SCTKLRE 544
Query: 391 -----KRVLALPGKPPFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHI 432
+ L + + FQT F E+ GDL I
Sbjct: 545 FQREFQLSYFLSPHANIIDTYNVAFQTRSSYVFAQEHAVLGDLFDAI 685
>13305
Length = 549
Score = 32.3 bits (72), Expect = 0.63, Method: Composition-based stats.
Identities = 15/45 (33%), Positives = 24/45 (53%), Gaps = 1/45 (2%)
Frame = +2
Query: 507 YIAPEIIAYQPYGKSVDWWAFGVLLYEMLA-GQAPFEGEDEDELF 550
++A E + Y D W+FGV+L+E+ G P+ D +LF
Sbjct: 23 WMAVESLFNNTYTTQSDVWSFGVVLWEIFTLGGTPYSSTDTQQLF 157
>26052
Length = 562
Score = 32.3 bits (72), Expect = 0.71, Method: Composition-based stats.
Identities = 16/28 (57%), Positives = 18/28 (64%)
Frame = -1
Query: 344 FLMVLGKGSFGKVMLSERKGTDELYAVK 371
F +LG GSFGKVM + K T E AVK
Sbjct: 379 FXKLLGVGSFGKVMALQHKDTGETLAVK 296
>29360
Length = 363
Score = 32.0 bits (71), Expect = 0.93, Method: Compositional matrix adjust.
Identities = 30/119 (25%), Positives = 55/119 (46%), Gaps = 5/119 (4%)
Frame = +3
Query: 361 RKGTDELYAVKILKKD-VVIQDDDVECTMVEKRVLALPGKPPFLTQLHSCFQTMDRLYFV 419
+KGT E+ A+KILK + +E +++++ F+ CFQ + V
Sbjct: 15 KKGTSEIVAIKILKNHPSYARQGQIEVSILQRLSQESADDYNFVRAF-ECFQHKNHTCLV 191
Query: 420 MEYVNGGDLMYHIQQVGRFKEPHAVFY----AAEIAIGLFFLQSKGIIYRDLKLDNVML 474
E + +Y + +F +P + Y ++ L L+ G+I+ DLK +N+ML
Sbjct: 192 FEMLEQN--LYDFLKQNKF-QPLPLKYIRPITQQVLTALRKLKQLGLIHADLKPENIML 359
>17637
Length = 447
Score = 30.8 bits (68), Expect = 1.9, Method: Composition-based stats.
Identities = 20/79 (25%), Positives = 37/79 (46%), Gaps = 2/79 (2%)
Frame = +1
Query: 507 YIAPEIIAYQPYGKSVDWWAFGVLLYEMLA-GQAPFEGEDEDELFQSIME-HNVAYPKSM 564
+++ E + Y + D W+FGVL++EM G+ P+ D E+ + + + +A P +
Sbjct: 115 WLSLEALQKSHYNEGSDVWSFGVLMWEMCTLGKLPYAEIDPYEMEHYLKDGYRLAQPFNC 294
Query: 565 SKEAVAICKGLMTKHPGKR 583
E I P +R
Sbjct: 295 PDELFTIMAYCWASMPAER 351
>33692
Length = 426
Score = 29.6 bits (65), Expect = 3.8, Method: Composition-based stats.
Identities = 13/31 (41%), Positives = 15/31 (48%), Gaps = 1/31 (3%)
Frame = -1
Query: 50 CSHCTDFIWGFGKQGFQCQVCC-FVVHKRCH 79
C + WG QGFQC CC +VV H
Sbjct: 228 CRNLLSSFWGKVSQGFQCLNCCWYVVRNTLH 136
>36976
Length = 442
Score = 29.3 bits (64), Expect = 4.9, Method: Compositional matrix adjust.
Identities = 26/102 (25%), Positives = 46/102 (45%), Gaps = 1/102 (0%)
Frame = +1
Query: 77 RCHEFVTFSCPGADKGPASDDPRSKHKFKIHTYSSPTFCDHCGSLLYGLIHQGMKCDTCM 136
+C E + +C +GP SD+P + K + T + P CD C L DT +
Sbjct: 37 KCGEPSSATC----QGPGSDEPATSDKTXLSTAARPHVCDVCFKTFTTLSDHK---DTWL 195
Query: 137 MNVHKRC-VMNVPSLCGTDHTERRGRIYIQAHIDRDVLIVLV 177
++++++ V +V S T+ +E + I R L+ V
Sbjct: 196 IHINQKPFVCDVCSKTCTNSSELKRHKLIHTMTSRKNLVCDV 321
>36388
Length = 834
Score = 29.3 bits (64), Expect = 6.0, Method: Compositional matrix adjust.
Identities = 14/31 (45%), Positives = 18/31 (58%), Gaps = 4/31 (12%)
Frame = +2
Query: 58 WGFGKQGFQCQVCCFVVHK--RCH--EFVTF 84
WG+G F+C++CCF H CH F TF
Sbjct: 257 WGWGDHNFKCRICCFQFHWVLSCHLXXFQTF 349
>26304
Length = 1290
Score = 28.5 bits (62), Expect = 8.4, Method: Compositional matrix adjust.
Identities = 16/50 (32%), Positives = 24/50 (48%), Gaps = 7/50 (14%)
Frame = +3
Query: 193 DPYVKLKLIPD------PKSESKQKTKTIKCSLNPEW-NETFRFQLKESD 235
DPYVKL ++P P + ++ + NP W NETF + +D
Sbjct: 906 DPYVKLTVVPSKSYPEKPHHHRELRSSVCPSTTNPVWDNETFTLEAYVTD 1055
>08416
Length = 1551
Score = 28.5 bits (62), Expect = 8.8, Method: Compositional matrix adjust.
Identities = 21/63 (33%), Positives = 27/63 (42%), Gaps = 11/63 (17%)
Frame = -3
Query: 84 FSCPGADKGPASDDPRSKHKFKIHTYSSPTFCDHCGSL---------LYGLIHQGMK--C 132
F+C +K A + HK IHT + P CD CG + Y IH G + C
Sbjct: 958 FACDVCNKSFARRHHLTHHKL-IHTDNKPFVCDVCGKIKIIFKSXLKXYYXIHTGQQPVC 782
Query: 133 DTC 135
D C
Sbjct: 781 DVC 773
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000229471 | hsapiens_gene_ensembl | Proto-oncogene
tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn) (Protooncogene
Syn) (SLK). [Source:Uniprot/SWISSPROT;Acc:P06241]
(482 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
21808 318 5e-88
06405 249 1e-66
11780 147 3e-55
04852 148 6e-36
09007 142 2e-34
17300 123 2e-33
20640 124 6e-29
07291 122 3e-28
14116 117 9e-27
08294 104 8e-23
18996 99 6e-21
07940 97 1e-20
22005 82 3e-20
17637 93 3e-19
01718 86 3e-17
13592 82 4e-16
14477 80 2e-15
13305 80 3e-15
00715 77 2e-14
01756 73 2e-13
17253 72 4e-13
19301 70 2e-12
01707 69 6e-12
29581 67 2e-11
12721 66 2e-11
01060 66 2e-11
18484 63 2e-10
25550 63 2e-10
18921 63 3e-10
14420 62 5e-10
04591 61 9e-10
27546 61 1e-09
14126 60 2e-09
00300 59 4e-09
11228 59 6e-09
00392 59 6e-09
01966 58 7e-09
07836 57 2e-08
31885 57 2e-08
13066 56 3e-08
12672 54 2e-07
13212 53 3e-07
09606 52 4e-07
04138 52 4e-07
21079 51 8e-07
29243 51 9e-07
12324 49 4e-06
19094 49 6e-06
30755 48 1e-05
15910 48 1e-05
26560 46 3e-05
03240 46 3e-05
21210 45 4e-05
29687 45 6e-05
19761 45 8e-05
11185 44 1e-04
14257 42 5e-04
28638 42 5e-04
28095 42 7e-04
12786 41 9e-04
26711 41 0.001
05206 41 0.001
01494 41 0.001
37602 41 0.001
32000 40 0.002
18481 40 0.003
32264 39 0.004
35671 39 0.006
16716 38 0.010
17286 38 0.011
16708 38 0.012
30740 37 0.014
27405 37 0.017
38046 37 0.020
06462 36 0.033
21433 36 0.044
01392 35 0.049
07933 35 0.061
18881 35 0.062
13664 35 0.064
31789 34 0.13
02638 34 0.14
29360 34 0.16
37260 33 0.18
00394 32 0.55
18401 32 0.82
17516 31 0.87
13641 31 1.0
27287 31 1.2
23319 31 1.3
29590 30 1.9
36481 30 2.5
27562 29 3.3
18050 28 6.4
15741 28 7.0
18663 28 7.2
>21808
Length = 1011
Score = 318 bits (816), Expect(2) = 5e-88, Method: Compositional matrix adjust.
Identities = 152/225 (67%), Positives = 180/225 (80%), Gaps = 1/225 (0%)
Frame = +1
Query: 233 GTWNGNTKVAIKTLKPGTMSPESFLEEAQIMKKLKHDKLVQLYAVVSEE-PIYIVTEYMN 291
G WN T VAIKTLK GTM P+ FL EAQIMKKL+H KL+QLYAV +++ PI+I+TE M
Sbjct: 4 GLWNNTTPVAIKTLKSGTMDPKDFLAEAQIMKKLRHPKLIQLYAVCTQDDPIFIITELMK 183
Query: 292 KGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKI 351
GSLL+FL+ G+GR LKLP L+D+ AQ+A GMAY+E NYIHRDL + NILV + KI
Sbjct: 184 NGSLLEFLQ-GKGRVLKLPALIDIGAQIACGMAYLESQNYIHRDLAARNILVSDNNTVKI 360
Query: 352 ADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVP 411
ADFGLAR+I+++EY AR GA+FPIKWTAPEAA Y RFTIKSDVWSFGILLTE VT GRVP
Sbjct: 361 ADFGLARVIKEDEYEARVGARFPIKWTAPEAANYNRFTIKSDVWSFGILLTETVTYGRVP 540
Query: 412 YPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKKDPEERP 456
YPGM N EVL QVE GYRMPCP CP L+++M+ CW+K+ ERP
Sbjct: 541 YPGMTNAEVLHQVEHGYRMPCPPGCPKPLYDIMLECWRKEEMERP 675
Score = 25.0 bits (53), Expect(2) = 5e-88, Method: Compositional matrix adjust.
Identities = 11/22 (50%), Positives = 14/22 (63%)
Frame = +2
Query: 456 PTFEYLQSFLEDYFTATEPQYQ 477
PTFE LQ LE++FT Y+
Sbjct: 674 PTFETLQWKLEEFFTMDSKDYR 739
>06405
Length = 1965
Score = 249 bits (637), Expect = 1e-66, Method: Compositional matrix adjust.
Identities = 143/350 (40%), Positives = 197/350 (56%), Gaps = 57/350 (16%)
Frame = +1
Query: 177 ESETTKGAYSLSIRDWDDMKGDHVKHYKIRKLDNGGYYITTRAQFETLQQLVQHYSGTWN 236
ESE++ G S+S+R +G V HY+I + D+G ++T +F TL +LV H+S +
Sbjct: 1 ESESSPGQRSISVR----FEG-RVYHYRITE-DDGKVFVTQEHRFNTLAELVHHHSIHAD 162
Query: 237 G------------------------------NTKVAI----------------------- 243
G T++A+
Sbjct: 163 GLVTTLLYPAPKRQKPTVFGVSPEPDRWEIERTEIAMKHRLGGGQYGDVYEAMWKRYNKI 342
Query: 244 ---KTLKPGTMSPESFLEEAQIMKKLKHDKLVQLYAVVSEE-PIYIVTEYMNKGSLLDFL 299
KTLK TM+ FLEEA IMK++KH LVQL V + E P YIVTE+M G+LLD+L
Sbjct: 343 VAVKTLKEDTMALNDFLEEAAIMKEMKHPNLVQLLGVCTREPPFYIVTEFMPHGNLLDYL 522
Query: 300 KDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARL 359
+ L+ MA Q+A+GMAY+E N+IHRDL + N LV + + K+ADFGLARL
Sbjct: 523 RSSTREENGPTALMYMATQIASGMAYLETKNFIHRDLAARNCLVADSNMVKVADFGLARL 702
Query: 360 IEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNRE 419
++D+ YTA GAKFPIKWTAPE + RF+ +SD+W+FG+LL EL T G PYPG+ E
Sbjct: 703 MKDDTYTAHIGAKFPIKWTAPEGLAFNRFSTRSDIWAFGVLLWELATYGMSPYPGVELTE 882
Query: 420 VLEQVERGYRMPCPQDCPISLHELMIHCWKKDPEERPTFEYLQSFLEDYF 469
V +ERGYRM P P ++ LM+ CW+ DP++RPTF+ + LE+ F
Sbjct: 883 VYHLLERGYRMERPPGTPADVYILMLKCWQWDPKDRPTFKEIHFLLENMF 1032
>11780
Length = 1713
Score = 147 bits (371), Expect(2) = 3e-55, Method: Compositional matrix adjust.
Identities = 106/340 (31%), Positives = 160/340 (47%), Gaps = 60/340 (17%)
Frame = +3
Query: 103 FHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYVAP--VDSIQAEEWYFGKLGRKDAE 160
F KG+ I ++ W + G G IP+NYV P V ++ A W+ GK+ R+ AE
Sbjct: 111 FQKGDLLVIRRATSDRMWYKACDSNGREGMIPANYVQPRKVVTLHAMPWFHGKITRQQAE 290
Query: 161 RQLLSFGNPR--GTFLIRESETTKGAYSLSI--------------------------RDW 192
L PR G FLIRES G Y+L + R+
Sbjct: 291 ELL----KPREDGLFLIRESSNYPGDYTLCVCHLGKVEHYRILYRENQLTIDEEGFFRNL 458
Query: 193 DDMKGDHVKHY-------------------------KIRKLDNGGYYITTRAQFETLQQL 227
D++ VKHY +++ +GG+ I + E + +
Sbjct: 459 DEL----VKHYLADADGLCTQLTRPVTKQGGNFGTVSLQEFKSGGWVIAXQ-DLEIGEAI 623
Query: 228 VQH-----YSGTWNGNTKVAIKTLKPGTMSPESFLEEAQIMKKLKHDKLVQLYAVVSEEP 282
+ Y G + G VAIK LK +SFL+EA +M L+HD LV+L VV E
Sbjct: 624 GKGDFGDVYKGMYRGQP-VAIKQLKDKDRGEQSFLQEASVMTSLRHDNLVRLIGVVLGET 800
Query: 283 IYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANIL 342
I++VTE+M KG+L+++L+ + + ++ A A M Y+E +HRDL + N+L
Sbjct: 801 IFLVTEFMGKGNLVEYLRSRGRSVITKKDQINFATDTCAAMEYLESKRLVHRDLAARNVL 980
Query: 343 VGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEA 382
V + K++DFGLA+ + ++ + KFPIKWTAPEA
Sbjct: 981 VHDDGKAKVSDFGLAKFGDFSQTS----VKFPIKWTAPEA 1088
Score = 86.7 bits (213), Expect(2) = 3e-55, Method: Compositional matrix adjust.
Identities = 41/86 (47%), Positives = 57/86 (66%)
Frame = +1
Query: 387 RFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIH 446
+FT KSD+WSFGILL E+ + GRVPYP + +V+ VERGYRM P+ CP ++ +M
Sbjct: 1102 KFTSKSDMWSFGILLWEIYSFGRVPYPRIPLTDVVMHVERGYRMEAPEGCPPEIYSIMKQ 1281
Query: 447 CWKKDPEERPTFEYLQSFLEDYFTAT 472
W+ DP ERPTF+ + + L + T
Sbjct: 1282 AWELDPNERPTFKSVLARLNNQRAVT 1359
>04852
Length = 1462
Score = 148 bits (373), Expect = 6e-36, Method: Compositional matrix adjust.
Identities = 87/259 (33%), Positives = 136/259 (52%), Gaps = 31/259 (11%)
Frame = +1
Query: 239 TKVAIKTLKPGTMSPE--SFLEEAQIMKKLK----HDKLVQLYAVVSEE-PIYIVTEYMN 291
+ VA+K L+ + E F++E Q+MK +K H +V ++ P++++ E+
Sbjct: 22 STVAVKMLRDIVTAVEEQDFVQELQVMKAVKKMGSHINIVNFLGCCTQGGPLWVIVEFAK 201
Query: 292 KGSLLDFL---KDG--------------------EGRALKLPNLVDMAAQVAAGMAYIER 328
G+L DFL +DG G ++ NL+ A Q+A GM ++
Sbjct: 202 NGNLRDFLESCRDGINGYGKFVSPQDPGWYTKTPGGHVIRRKNLLSYAFQIARGMEFLAS 381
Query: 329 MNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRF 388
IHRDL + N+LV + KIADFGL+R + Y R G + P+KW APEA R+
Sbjct: 382 RKCIHRDLAARNVLVTEEHVLKIADFGLSR--TGDYYKKRSGGRLPVKWMAPEALFDMRY 555
Query: 389 TIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQ-VERGYRMPCPQDCPISLHELMIHC 447
T KSDVWSFG++L E+ + G +PY + N E+ + ++ YRMP P+ +L+ +M C
Sbjct: 556 TTKSDVWSFGVVLWEIFSLGGMPYASIPNEELYSKLLDDAYRMPRPELASGNLYAIMERC 735
Query: 448 WKKDPEERPTFEYLQSFLE 466
W P +RP F L ++
Sbjct: 736 WLNRPSDRPEFSQLVGHID 792
>09007
Length = 1440
Score = 142 bits (359), Expect = 2e-34, Method: Compositional matrix adjust.
Identities = 91/272 (33%), Positives = 146/272 (53%), Gaps = 11/272 (4%)
Frame = -1
Query: 218 RAQFETLQQLVQHYSGTWNGNTKVAIKTLKPGTMSP--ESFLEEAQIMKKLKHDKLVQLY 275
+ F T++Q + ++ +VA+K L + + FL+E IM+ L H+ +V++Y
Sbjct: 849 QGHFGTVRQAI--WTAESGEKVQVAVKCLSKDKIHKDGQEFLKETAIMQMLDHENIVRVY 676
Query: 276 AVVSEE--PIYIVTEYMNKGSLLDFLKDGEGRA-LKLPNLVDMAAQVAAGMAYIERMNYI 332
VV + I +VTE SLL+ +K+ R +P L D + QV GM+Y+E +
Sbjct: 675 GVVMDNGADIMLVTELAPMRSLLECVKEVSARVDFSVPRLCDFSQQVCDGMSYLESKRLV 496
Query: 333 HRDLRSANILVGNGLICKIADFGLA-RLIEDNEYTARQGA---KFPIKWTAPEAALYGRF 388
HRDL + NIL+ + KI+D G++ L EY Q + + W APE+ F
Sbjct: 495 HRDLAARNILLFSKSKVKISDVGVSGALGAGKEYYQSQQTIHLQNAVAWCAPESFRNLCF 316
Query: 389 TIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVE--RGYRMPCPQDCPISLHELMIH 446
+ SDVW+FG+LL E T G P+ G+N ++++E V+ + R+ P CP + +M+
Sbjct: 315 SSASDVWAFGVLLWEFFTHGFQPWAGLNGQQIMEAVDAPQSQRLEQPDLCPKEYYAVMLK 136
Query: 447 CWKKDPEERPTFEYLQSFLEDYFTATEPQYQP 478
CW+++P+ RPTF L FL T PQ +P
Sbjct: 135 CWEQEPQRRPTFSQL--FL------TLPQIRP 64
>17300
Length = 480
Score = 123 bits (308), Expect(2) = 2e-33, Method: Compositional matrix adjust.
Identities = 56/117 (47%), Positives = 83/117 (70%), Gaps = 4/117 (3%)
Frame = +1
Query: 319 VAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDN----EYTARQGAKFP 374
+++GM + M Y+HRDL + NILV L+CK+ADFGL+R IE + YT + G K P
Sbjct: 1 ISSGMGXLADMGYVHRDLAARNILVNEILVCKVADFGLSREIESDTTEGAYTTK-GGKIP 177
Query: 375 IKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMP 431
++WTAPEA Y +FT SDVWSFG+++ E+++ G PY +N++V++ VE+GYR+P
Sbjct: 178 VRWTAPEAIAYRKFTSASDVWSFGVVMWEVMSYGERPYWNWSNQDVIKAVEKGYRLP 348
Score = 38.1 bits (87), Expect(2) = 2e-33, Method: Composition-based stats.
Identities = 16/43 (37%), Positives = 23/43 (53%), Gaps = 1/43 (2%)
Frame = +2
Query: 432 CPQ-DCPISLHELMIHCWKKDPEERPTFEYLQSFLEDYFTATE 473
CP DCP +LH+LM+ W+K+ RP + L+ A E
Sbjct: 344 CPSMDCPEALHQLMLDAWQKERSHRPKMSMVVKTLDKLIRAPE 472
>20640
Length = 1492
Score = 124 bits (312), Expect = 6e-29, Method: Compositional matrix adjust.
Identities = 59/144 (40%), Positives = 86/144 (59%), Gaps = 1/144 (0%)
Frame = +1
Query: 331 YIHRDLRSANILVGNGLICKIADFGLARLIED-NEYTARQGAKFPIKWTAPEAALYGRFT 389
Y+HRDL + N LVG+ L+ KI+DFGLAR + + Y + PI+W EA LY +F+
Sbjct: 7 YVHRDLATRNCLVGHDLVVKISDFGLARSVHSVDYYRGSEHDAIPIRWMPLEAILYNKFS 186
Query: 390 IKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWK 449
+SDVWSFG++L E+ PY G+ + EV+ V+ G + CP+ P ++ELM CW
Sbjct: 187 TQSDVWSFGVVLWEIFAFALQPYYGLTHEEVVRFVKEGKVLACPERTPPPMYELMKQCWH 366
Query: 450 KDPEERPTFEYLQSFLEDYFTATE 473
+ P RP+F L LE+ + E
Sbjct: 367 RRPATRPSFHTLHKTLENMHSKYE 438
>07291
Length = 833
Score = 122 bits (306), Expect = 3e-28, Method: Compositional matrix adjust.
Identities = 60/167 (35%), Positives = 98/167 (58%), Gaps = 2/167 (1%)
Frame = +1
Query: 304 GRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLA-RLIED 362
+ L + L+D Q+A GMAY++ + +HR+L + N +V +++D+G+ L
Sbjct: 31 SKMLTVVQLLDFGRQIADGMAYLQEVKVVHRNLAARNCIVTEDGRLQLSDYGVTGSLFPQ 210
Query: 363 NEYTARQG-AKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVL 421
+ YTA A+ +KW APE F+ KSDVW+FG++L EL+T+G PYP + N +L
Sbjct: 211 SYYTADDSPARDLVKWMAPETIDNFHFSSKSDVWAFGVVLWELLTRGITPYPDVENSSLL 390
Query: 422 EQVERGYRMPCPQDCPISLHELMIHCWKKDPEERPTFEYLQSFLEDY 468
++ G+RM P+ P ++E+M CW + PE+RP F L L+ +
Sbjct: 391 PYLKEGHRMKKPKQSPEPVYEMMTACWNESPEQRPDFAELNDQLKTF 531
>14116
Length = 1017
Score = 117 bits (294), Expect = 9e-27, Method: Compositional matrix adjust.
Identities = 65/185 (35%), Positives = 107/185 (57%), Gaps = 8/185 (4%)
Frame = -1
Query: 237 GNTKVAIKTL---KPGTMSPESFLEEAQIMKKLKHDKLVQLYAV---VSEEPIYIVTEYM 290
G+ VA+KTL P + +SFL+EA IMK H ++ L + + + P+ +V +M
Sbjct: 552 GDILVAVKTLHNNNPREIELQSFLQEALIMKDFHHSNVLTLIGICLNLDDMPL-VVLPFM 376
Query: 291 NKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICK 350
G LL +++D + + + +L+ +A GM Y+ + ++HRDL + N ++ K
Sbjct: 375 KHGDLLTYIRDDQHQP-TIKDLIMYGVDIARGMDYLAGLKFVHRDLAARNCMLDEDFHVK 199
Query: 351 IADFGLARLIEDNEYTARQG--AKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKG 408
+ADFGLAR I + EY + + AK P+KW A E+ G + K+DVWS+G++L EL+T+G
Sbjct: 198 VADFGLARDIYEKEYYSSENKKAKLPVKWMALESLEKGNYDSKTDVWSYGVVLWELLTRG 19
Query: 409 RVPYP 413
P
Sbjct: 18 SDALP 4
>08294
Length = 1849
Score = 104 bits (259), Expect = 8e-23, Method: Compositional matrix adjust.
Identities = 64/206 (31%), Positives = 100/206 (48%), Gaps = 11/206 (5%)
Frame = +2
Query: 271 LVQLYAVVSE-EPIYIVTEYMNKGSLLDFL-----KDGEGRALKLPNL-----VDMAAQV 319
+V V E EP +++TEY + G L FL +G GR ++P L + M QV
Sbjct: 893 IVHFMGVCREAEPHFLITEYCDWGDLKQFLLATRNDNGRGRGTRVPALALSQKLGMGQQV 1072
Query: 320 AAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTA 379
AAGM + +H DL + N+L+ + + K+A L+ + +EY P++W
Sbjct: 1073 AAGMEALSNQGLVHGDLAARNVLLTSRMQLKVARPALSGDVYASEYYPLHQRLVPLRWLP 1252
Query: 380 PEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPIS 439
PE L T DVW+FG+ L E++ +PY M++ EVL ++ D P +
Sbjct: 1253 PEGVLEDSATTCGDVWAFGVFLWEVLQLADLPYRLMSDEEVLRSLQHSQAALDSPDAPPA 1432
Query: 440 LHELMIHCWKKDPEERPTFEYLQSFL 465
L L+ C + P +RP F + S L
Sbjct: 1433 LLSLLQRCTAQQPSQRPPFSEICSVL 1510
>18996
Length = 491
Score = 98.6 bits (244), Expect = 6e-21, Method: Compositional matrix adjust.
Identities = 55/136 (40%), Positives = 79/136 (58%), Gaps = 6/136 (4%)
Frame = +2
Query: 332 IHRDLRSANILVGNGLICKIADFGLARLIE-DNEYTARQGAKFPIKWTAPEAALYGRFTI 390
IHRDL + NILV + KI+DFGLA+ D Y PIKW +PEA +F+
Sbjct: 2 IHRDLAARNILVDRSCV-KISDFGLAQFANADGYYYGISQRDIPIKWYSPEAIETCKFSS 178
Query: 391 KSDVWSFGILLTELVTKGRVP--YPG--MNNREVLEQVERGYRMPCPQDCPISLH-ELMI 445
SDVWS+G+ L E+ ++G +P PG + E L ++ +G R+P P+ C ++ ELM
Sbjct: 179 YSDVWSYGVTLFEMFSRGEIPNLLPGHDLTQEEFLNRLRKGERLPKPELCSDFVYSELMR 358
Query: 446 HCWKKDPEERPTFEYL 461
CW + P+ RPTF +
Sbjct: 359 PCWHEMPKSRPTFHQI 406
>07940
Length = 1336
Score = 97.4 bits (241), Expect = 1e-20, Method: Compositional matrix adjust.
Identities = 49/112 (43%), Positives = 68/112 (60%), Gaps = 1/112 (0%)
Frame = -3
Query: 305 RALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNE 364
+ L +L+ A QVA GM Y+ IHRDL + N+LV + KIADFGL R ++ +
Sbjct: 362 KMLTPKDLISYAYQVARGMEYLASKQCIHRDLAARNVLVAEEYVLKIADFGLTRNLQQFD 183
Query: 365 YTARQ-GAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGM 415
Y + + P+KW APEA ++T KSDVWS+G+LL E+ T G PYP +
Sbjct: 182 YYRKTTDGRLPVKWMAPEALFDRKYTSKSDVWSYGVLLWEIFTLGGNPYPSV 27
Score = 36.6 bits (83), Expect = 0.022, Method: Compositional matrix adjust.
Identities = 21/69 (30%), Positives = 36/69 (52%), Gaps = 4/69 (5%)
Frame = -3
Query: 236 NGNTKVAIKTLKPGTMSPE--SFLEEAQIMKKL-KHDKLVQLYAVVSEE-PIYIVTEYMN 291
N + VA+K LK E + E ++MK + KH ++ L ++ +Y++ E+
Sbjct: 758 NNSVTVAVKMLKEDATDREMMDLIREMEMMKVIGKHKNIINLLGCCTQRGALYVIVEFAP 579
Query: 292 KGSLLDFLK 300
G+L DFLK
Sbjct: 578 HGNLRDFLK 552
>22005
Length = 873
Score = 82.4 bits (202), Expect(2) = 3e-20, Method: Compositional matrix adjust.
Identities = 58/194 (29%), Positives = 91/194 (46%), Gaps = 44/194 (22%)
Frame = +1
Query: 256 FLEEAQIMKKLKHDKLVQLYAVVS-EEPIYIVTEYMNKGSLLDFLKDGEGRALKLP---- 310
F EA +M H +V+L V + +P+ ++ E+M+KG L DFL+ LP
Sbjct: 151 FEREASLMADFDHPNIVKLLGVCAIGKPMCLLFEFMSKGDLNDFLRLCSPENYNLPVSRS 330
Query: 311 -NLVD-------------------------------------MAAQVAAGMAYIERMNYI 332
NLV ++ Q++AGMAY+ + +Y+
Sbjct: 331 QNLVVDLEDGLRVEVEAEECEKDTQSEDRDCSGMLXTKDQLYISQQISAGMAYLAQKDYV 510
Query: 333 HRDLRSANILVGNGLICKIADFGLARLIEDNEY-TARQGAKFPIKWTAPEAALYGRFTIK 391
HRDL + + I+DFGLAR + +Y + PI+W EA LY +F+ +
Sbjct: 511 HRDL-ATRTVXSRTT*S*ISDFGLARSVHSVDYYRGSEQDAIPIRWMPLEAILYSKFSTQ 687
Query: 392 SDVWSFGILLTELV 405
SDVWSFG++L E++
Sbjct: 688 SDVWSFGVVLWEIL 729
Score = 34.3 bits (77), Expect(2) = 3e-20, Method: Compositional matrix adjust.
Identities = 15/42 (35%), Positives = 24/42 (57%)
Frame = +3
Query: 411 PYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKKDP 452
PY G+ + EV+ V+ G + P P ++ELM CW++ P
Sbjct: 744 PYYGLTHEEVVNYVKAGKILEQPTKTPHQVYELMKQCWQRRP 869
>17637
Length = 447
Score = 92.8 bits (229), Expect = 3e-19, Method: Compositional matrix adjust.
Identities = 46/132 (34%), Positives = 74/132 (56%), Gaps = 1/132 (0%)
Frame = +1
Query: 340 NILVGNGLICKIADFGLARLIEDNEYTARQGAKF-PIKWTAPEAALYGRFTIKSDVWSFG 398
N ++ + L K+ D L+R + +Y ++ PIKW + EA + SDVWSFG
Sbjct: 1 NCVIDDQLRVKLTDSALSRDLFSGDYNCLGDGEYRPIKWLSLEALQKSHYNEGSDVWSFG 180
Query: 399 ILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKKDPEERPTF 458
+L+ E+ T G++PY ++ E+ ++ GYR+ P +CP L +M +CW P ERP+F
Sbjct: 181 VLMWEMCTLGKLPYAEIDPYEMEHYLKDGYRLAQPFNCPDELFTIMAYCWASMPAERPSF 360
Query: 459 EYLQSFLEDYFT 470
LQ L ++ T
Sbjct: 361 SQLQICLSEFHT 396
>01718
Length = 959
Score = 85.9 bits (211), Expect = 3e-17, Method: Compositional matrix adjust.
Identities = 77/245 (31%), Positives = 119/245 (48%), Gaps = 18/245 (7%)
Frame = +3
Query: 243 IKTLKPGTMSP--ESFLEEAQIMKKLKHDKLVQLYAV-VSEEPIYIVTEYMNKGSLLDFL 299
+ LK TM+ + L E Q++ +L+H +++ V V E ++ +TEY+ G+L L
Sbjct: 228 VMALKMNTMTSNRHNMLREVQLLNRLQHANILRFMGVCVHEGQLHALTEYIPSGNLEQLL 407
Query: 300 --KDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILV----GNGLICKIAD 353
KD E L + + +A G+ Y+ +IHRDL S NIL+ +G IAD
Sbjct: 408 EKKDEE---LPWTQRIQLTLGLARGLDYLHSTRFIHRDLTSKNILIRREDNHGYHAVIAD 578
Query: 354 FGLARLIE---DNEYTARQGAKFPIKWTAPEAALYGRF-TIKSDVWSFGILLTELVTKGR 409
FGLA I D E G+ + W APE L G F ++D++S GI++ E+ R
Sbjct: 579 FGLATKIPDPLDKEKLPTVGSPY---WMAPE-VLNGHFYNERADLFSVGIIMCEIT--AR 740
Query: 410 VP-----YPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKKDPEERPTFEYLQSF 464
+P P MNN V + V + CP+ +L C + DP++RP + +
Sbjct: 741 IPADPDIMPRMNNFGV-DYVALSEMI---SYCPLDYLQLAFKCCQVDPQKRPRGVEIIEW 908
Query: 465 LEDYF 469
LE F
Sbjct: 909 LEKIF 923
>13592
Length = 980
Score = 82.4 bits (202), Expect = 4e-16, Method: Compositional matrix adjust.
Identities = 65/252 (25%), Positives = 126/252 (50%), Gaps = 14/252 (5%)
Frame = +2
Query: 218 RAQFETLQQLVQHYSGTWNGNTKVAIKTLKPG-TMSPESFLEEAQIMKKLKHDKLVQLYA 276
+ +F + V + +G ++AI+ PG T + ++ EE +I++ +KH LV+ Y
Sbjct: 14 QGRFGKVYTAVNNNTGELMAMKEIAIQ---PGETRALKNVAEELKILEGIKHKNLVRYYG 184
Query: 277 V-VSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVD--MAAQVAAGMAYIERMNYIH 333
+ V E + I E ++G+L ++ G LP + AQ+ +G+A + + +H
Sbjct: 185 IEVHREELLIFMELCSEGTLESLVELTGG----LPEALSRRFTAQLLSGVAELHKHGIVH 352
Query: 334 RDLRSANILVGNGL-ICKIADFGLARLIEDNE--------YTARQGAKFPIKWTAPEAAL 384
RD+++ANI + +G K+ DFG A I+ + Y Q P +T +
Sbjct: 353 RDIKTANIFLVDGSNSLKLGDFGSAVKIQAHTTVPGELQGYVGTQAYMAPEVFTKTNSDG 532
Query: 385 YGRFTIKSDVWSFGILLTELVTKGRVPYPGMN-NREVLEQVERGYRMPCPQDCPISLHEL 443
+GR +D+WS G ++ E+ + G+ P+ + N +++ +V G + P+ H+
Sbjct: 533 HGRL---ADIWSVGCVVVEMAS-GKRPWAQFDSNFQIMFKVGMGEKPQAPESLSQEGHDF 700
Query: 444 MIHCWKKDPEER 455
+ HC + DP++R
Sbjct: 701 IDHCLQHDPKQR 736
>14477
Length = 493
Score = 79.7 bits (195), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 47/135 (34%), Positives = 79/135 (58%), Gaps = 5/135 (3%)
Frame = -1
Query: 241 VAIKTLKPGTMSPE---SFLEEAQIMKKLKHDKLVQLYAVVSEEPIYIVTEYMNKGSLLD 297
VAIK LK + P ++EA++MKK+ H +V+L + E + +V E G L
Sbjct: 400 VAIKVLKNADLDPSVQSELIKEAEVMKKMDHMHIVRLIGLCEGETMMLVLELAKLGPLNK 221
Query: 298 FLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLA 357
FL + + L L N++++ QV+ GM Y+E ++HRDL + NIL+ + KI+DFG++
Sbjct: 220 FLP--KNKHLPLWNILELMWQVSQGMEYLEANKFVHRDLAARNILLCDEHFAKISDFGMS 47
Query: 358 RLI--EDNEYTARQG 370
+ + E+N Y A++
Sbjct: 46 KTLSRENNYYMAQEA 2
>13305
Length = 549
Score = 79.7 bits (195), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 35/102 (34%), Positives = 59/102 (57%), Gaps = 4/102 (3%)
Frame = +2
Query: 370 GAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYR 429
+ PI+W A E+ +T +SDVWSFG++L E+ T G PY + +++ ++ GYR
Sbjct: 2 STRVPIRWMAVESLFNNTYTTQSDVWSFGVVLWEIFTLGGTPYSSTDTQQLFAFLKDGYR 181
Query: 430 MPCPQDCPISLHELMIHCWKKDPEERPTFE----YLQSFLED 467
+ P+ C + + +M+ CW ++ + RPTF LQ L+D
Sbjct: 182 LKRPKLCDQNTYAMMLQCWNENAQRRPTFPELCGRLQRMLDD 307
>00715
Length = 1788
Score = 76.6 bits (187), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 62/223 (27%), Positives = 103/223 (46%), Gaps = 31/223 (13%)
Frame = +1
Query: 266 LKHDKLVQLYAVVS----EEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAA 321
L+H +V + S E+ ++ EY+ +L L D + + + + +A Q+A
Sbjct: 97 LRHVNVVSILGATSLHRFEDGAWLAMEYVGPLNLQTILNDHQ-QDIDSSMRLSLALQMAR 273
Query: 322 GMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLI----------------EDNEY 365
G+ Y+ +N +H DL+ AN L+ L +IADFG + + E
Sbjct: 274 GLHYLHSINIVHLDLKPANCLLTRDLKLRIADFGCCHQLTPTGLDMGEREGGMAGNELEL 453
Query: 366 TARQGA-----KFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREV 420
T QGA + + APE + +++SDV+S GI L ++ T+ + PY G+ V
Sbjct: 454 TPVQGAWKNELAGTLAYRAPELLKGLQPSVRSDVYSLGITLWQMCTR-QGPYEGVPAHAV 630
Query: 421 LEQVERGYRMPCP----QDCP--ISLHELMIHCWKKDPEERPT 457
+ QV PCP +D P + +L CW + E+RPT
Sbjct: 631 VYQVVSKDLRPCPPPSTEDDPFEVMFRDLYTQCWARRVEDRPT 759
>01756
Length = 1858
Score = 73.2 bits (178), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 61/229 (26%), Positives = 102/229 (44%), Gaps = 16/229 (6%)
Frame = -3
Query: 198 DHVKHYKIRKLDNGGYYITTRAQFETLQQLVQHYSGTWNGNTKVAIKTLKPGTMSPESFL 257
+ K+ K+ K+ G + +A+ + +Q+V KV + K G P + L
Sbjct: 1748 EDAKYEKLAKIGQGTFGEVFKARCKKTKQVV--------AMKKVLMDNEKEGF--PITAL 1599
Query: 258 EEAQIMKKLKHDKLVQLYAVVSEEP---------IYIVTEYMNKGSLLDFLKDGEGRALK 308
E +I++ L H+ +V L + S + Y+V E+ L L
Sbjct: 1598 REIKILQLLNHENVVDLIEICSTKATSANRYKSMFYLVFEFCEHD--LAGLLSNMSVVFN 1425
Query: 309 LPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLAR-----LIEDN 363
LP + ++ Q+ G+ YI R +HRD+++ANIL+ + K+ADFGLAR L + N
Sbjct: 1424 LPEIKEVMKQLMNGLYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPN 1245
Query: 364 EYTARQGAKFPIKWTAPEAALYG--RFTIKSDVWSFGILLTELVTKGRV 410
YT R W P L G ++ D W G ++ E+ T+ +
Sbjct: 1244 RYTNR----VVTLWYRPPELLLGDRNYSTAIDQWGAGCIMAEMWTRNPI 1110
>17253
Length = 483
Score = 72.4 bits (176), Expect = 4e-13, Method: Compositional matrix adjust.
Identities = 45/153 (29%), Positives = 69/153 (45%), Gaps = 16/153 (10%)
Frame = -1
Query: 241 VAIKTLKPGTMSPES--FLEEAQIMKKL-KHDKLVQLYAVVS-EEPIYIVTEYMNKGSLL 296
VA+KT E FL E IM+KL +H +V + +P I+ E+ G LL
Sbjct: 459 VAVKTHNEAATDAEKSEFLRELSIMRKLPRHPNVVSFMGCCTMSDPALILMEFCCHGDLL 280
Query: 297 DFLKD----------GEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNG 346
FL+ L + A VA GMA++ +HRD+ + N+L+
Sbjct: 279 SFLRKRRPDRTVFLTSTANDLTARDFFSFALHVARGMAHVANNKIVHRDVAARNVLISER 100
Query: 347 LICKIADFGLARLIEDNE--YTARQGAKFPIKW 377
+CK++DFGL+R + D Y P++W
Sbjct: 99 NVCKVSDFGLSRRVGDQNDVYEIVSRRPLPLRW 1
>19301
Length = 712
Score = 69.7 bits (169), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 35/94 (37%), Positives = 55/94 (58%), Gaps = 1/94 (1%)
Frame = +2
Query: 263 MKKLKHDKLVQLYAVVSEEPIY-IVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAA 321
++KL H ++ V ++ P Y I+ EY G L + L+DG+ L ++D + Q+A+
Sbjct: 431 LRKLNHPNIISFKGVCTQAPCYCIIMEYCPYGQLYEVLRDGKEIPPAL--VLDWSKQIAS 604
Query: 322 GMAYIERMNYIHRDLRSANILVGNGLICKIADFG 355
GM Y+ IHRDL+S N+LV + KI+DFG
Sbjct: 605 GMNYLHSHKIIHRDLKSPNVLVAKNDVVKISDFG 706
>01707
Length = 757
Score = 68.6 bits (166), Expect = 6e-12, Method: Compositional matrix adjust.
Identities = 65/234 (27%), Positives = 114/234 (48%), Gaps = 8/234 (3%)
Frame = +1
Query: 201 KHYKIRKLDNGGYYITTRAQFETLQQLVQHYSGTWNGNTKVAIKTLKPGTMSP---ESFL 257
K+ KI K+ G Y + + + + QLV AIK P + +
Sbjct: 67 KYEKIGKIGEGSYGVVFKCRNKETSQLV-------------AIKKFVESEDDPLIKKIAM 207
Query: 258 EEAQIMKKLKHDKLVQLYAVVSEEP-IYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMA 316
E +++K+LKH LV+L V + +++V +Y++ +LL+ L D R L P + +
Sbjct: 208 REIRMLKQLKHPNLVRLIEVFRRKKRLHLVFDYVDH-TLLNEL-DRYPRGLPEPMVKRII 381
Query: 317 AQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIE--DNEYTARQGAKFP 374
Q + + + N IHRD++ NIL+ K+ DFG AR++ +EYT ++
Sbjct: 382 YQTLLAVNFCHQYNTIHRDVKPENILITRQGQVKLCDFGFARILTGPGDEYTDYVATRW- 558
Query: 375 IKWTAPEAALYG--RFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVER 426
+ APE L G ++ DVW+ G + EL+T G+ +PG ++ + L + +
Sbjct: 559 --YRAPE-LLVGDTQYGPPVDVWAIGCVFAELLT-GQALWPGRSDVDQLHLIRK 708
>29581
Length = 1278
Score = 66.6 bits (161), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 59/191 (30%), Positives = 91/191 (47%), Gaps = 11/191 (5%)
Frame = -2
Query: 246 LKPGTMSPESFLEEAQIMKKLKHDKLVQLYAVV---SEEPIYIVTEYMNK--GSLLDFLK 300
L+ +SP + + L+H +VQL VV S + +++V EY + SLLD +
Sbjct: 1244 LERDMVSPSVVCVRSTFLLNLRHQNIVQLQEVVVGKSLDSLFLVMEYCEQDLASLLDNMP 1065
Query: 301 DGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLI 360
+ + + Q+ G+ Y+ IHRDL+ +N+L+ + KIADFGLAR
Sbjct: 1064 APFSES----QVKCIVLQLLKGLRYLHEAFIIHRDLKVSNLLMTDKGCVKIADFGLAR-- 903
Query: 361 EDNEYTARQGAKFP----IKWTAPEAALYGRFTIKS--DVWSFGILLTELVTKGRVPYPG 414
Y Q P + + APE L+G T + D+WS G +L EL+ P
Sbjct: 902 ---NYGKPQKPMTPKVVTLWYRAPE-LLFGSKTHSTAIDMWSAGCILGELLGHK----PL 747
Query: 415 MNNREVLEQVE 425
M R L+Q+E
Sbjct: 746 MPGRSDLQQIE 714
>12721
Length = 821
Score = 66.2 bits (160), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 44/183 (24%), Positives = 86/183 (46%), Gaps = 2/183 (1%)
Frame = +1
Query: 254 ESFLEEAQIMKKLKHDKLVQLYA--VVSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPN 311
E E +M+ H +V++Y +V++E +++V E+M G+L D + + +++
Sbjct: 211 ELLFNEVVVMRDYHHPNIVEMYNSYLVNDE-LWVVMEFMEGGALTDIVTNNRMDEVQIAT 387
Query: 312 LVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGA 371
+ + +A++ IHRD++S +IL+ + K+ DFG + + +
Sbjct: 388 VCRACLK---ALAFLHANGVIHRDIKSDSILLSHDGKVKLXDFGFCAQVTQDLQKRKSLV 558
Query: 372 KFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMP 431
P W APE + + D+WS GI++ E++ P N L+ + R MP
Sbjct: 559 GTPY-WMAPEVISRLPYGPEVDIWSLGIMVMEMIDAE----PPFFNEPPLQAMRRIRDMP 723
Query: 432 CPQ 434
P+
Sbjct: 724 PPK 732
>01060
Length = 1800
Score = 66.2 bits (160), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 52/205 (25%), Positives = 97/205 (47%), Gaps = 7/205 (3%)
Frame = +1
Query: 253 PESFLEEAQIMKKLKHDKLVQLYAVVSE-EPIYIVTEYMNKGSLLDFLKDGEGRALKLPN 311
P S + E ++++L+H +V L V+ E E +++V E+++ + K EG L
Sbjct: 202 PSSAIREIAMLRELRHTNIVCLEDVIMEDERLFLVFEFLSMDLKMYIDKFPEGVVLDRRL 381
Query: 312 LVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGA 371
+ Q+ G+ + + +HRDL+ N+L+ + KIADFG+AR A
Sbjct: 382 VKSYVFQIVTGIXFCHQRRIVHRDLKPQNLLINHTGAIKIADFGMARTFA-LPVRAYTHE 558
Query: 372 KFPIKWTAPEAAL-YGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRM 430
+ + APE + +++ DVWS G + +++ + + + G + + L ++ R
Sbjct: 559 VVTLWYRAPEILMGASKYSTPVDVWSIGTIFADMLIRTPI-FKGDSEIDQLFKIFRIIGT 735
Query: 431 PCPQDCPISLHEL-----MIHCWKK 450
P Q P H+L M WK+
Sbjct: 736 PTEQTWP-EFHKLPAFNGMFPLWKE 807
>18484
Length = 635
Score = 63.2 bits (152), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 37/122 (30%), Positives = 65/122 (53%)
Frame = +1
Query: 303 EGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIED 362
EG+ K P AA++A G+ ++ I+RDL+ N+++ + KIADFG+ +
Sbjct: 25 EGK-FKEPVAAFYAAEIAVGLFFLHDQGIIYRDLKLDNVMLDSEGHIKIADFGMCKEGMT 201
Query: 363 NEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLE 422
+ T R P + APE LY ++ D W++G+LL E++ G+ P+ G + E+
Sbjct: 202 GDATTRTFCGTP-DYIAPEIVLYQPYSKSVDWWAYGVLLFEMLA-GQPPFDGEDEDELFS 375
Query: 423 QV 424
+
Sbjct: 376 SI 381
>25550
Length = 941
Score = 63.2 bits (152), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 29/60 (48%), Positives = 40/60 (66%)
Frame = +3
Query: 410 VPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKKDPEERPTFEYLQSFLEDYF 469
V YPG++ EV +ERGYRM PQ P ++ LM+ CW+ DP+ERPTF+ + LE+ F
Sbjct: 36 VXYPGVDLTEVYHLLERGYRMERPQGTPADVYILMLKCWQWDPKERPTFKEIHYLLENMF 215
>18921
Length = 697
Score = 63.2 bits (152), Expect = 3e-10, Method: Compositional matrix adjust.
Identities = 47/172 (27%), Positives = 80/172 (46%), Gaps = 1/172 (0%)
Frame = +2
Query: 241 VAIKTLKPGTMSPESFLEEAQIMKKLKHDKLVQLY-AVVSEEPIYIVTEYMNKGSLLDFL 299
+AIK + P + ++E IM++ +V+ Y + ++IV EY GS+ D +
Sbjct: 113 LAIKQV-PVDTDLQEIIKEISIMQQCDSKYIVKYYGSYFKNTDLWIVMEYCGAGSVSDIM 289
Query: 300 KDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARL 359
+ + L + + G+ Y+ IHRD+++ NIL+ N K+ADFG+A
Sbjct: 290 RL-RNKTLVEREIATILYYTLKGLXYLHSRRKIHRDIKAGNILLNNEGHAKLADFGVAGQ 466
Query: 360 IEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVP 411
+ D P W APE + +D+WS GI E+ +G+ P
Sbjct: 467 LTDTMAKRNTVIGTPY-WMAPEVIQEIGYDCVADIWSLGITALEM-AEGKPP 616
>14420
Length = 528
Score = 62.0 bits (149), Expect = 5e-10, Method: Compositional matrix adjust.
Identities = 39/162 (24%), Positives = 79/162 (48%), Gaps = 3/162 (1%)
Frame = +2
Query: 254 ESFLEEAQIMKKLKHDKLVQ-LYAVVSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNL 312
E + E +M++ ++ +V L + + E +++V E++ GSL D + + + +
Sbjct: 35 ELIINEILVMRENQNPNIVNYLDSYLVGEELWVVMEFLAGGSLTDVVTE---TCMDEGQI 205
Query: 313 VDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLI--EDNEYTARQG 370
+ + + ++ IHRD++S NIL+G K+ DFG + E ++ + G
Sbjct: 206 AAVCRECLQALEFLHENQVIHRDIKSDNILLGMDGSVKLTDFGFCAQLSPEQSKRSTMVG 385
Query: 371 AKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPY 412
+ W APE ++ D+WS G++ E++ +G PY
Sbjct: 386 TPY---WMAPEVVTRKQYGPTVDIWSLGVMCIEMI-EGEPPY 499
>04591
Length = 1117
Score = 61.2 bits (147), Expect = 9e-10, Method: Compositional matrix adjust.
Identities = 44/169 (26%), Positives = 83/169 (49%), Gaps = 14/169 (8%)
Frame = -2
Query: 253 PESFLEEAQIMKKLKHDKLVQLYAVVSEEP---------IYIVTEYMN--KGSLLDFLKD 301
P + L E +I+++L+H+ +VQL + + Y++ EY + LL+ L+
Sbjct: 1089 PITALREIKILQQLEHENVVQLQEICHTQAGPYNRYKSTFYLIFEYCDYDLAGLLNNLR- 913
Query: 302 GEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLAR-LI 360
L + ++ +Q+ G+ YI +HRD+++ANIL+ + K+ADFGL+R +
Sbjct: 912 ---VKFSLADKKNLMSQLLNGLFYIHTKQILHRDIKAANILLTRDGVLKLADFGLSRPWV 742
Query: 361 EDNEYTARQGAKFPIKWTAPEAALYG--RFTIKSDVWSFGILLTELVTK 407
+ T R W P L G + + D+W G ++ E+ ++
Sbjct: 741 KSKRLTNR----VVTLWYRPPELLLGEREYGPEIDMWGVGCIMAEMWSR 607
>27546
Length = 426
Score = 61.2 bits (147), Expect = 1e-09, Method: Composition-based stats.
Identities = 36/114 (31%), Positives = 56/114 (49%), Gaps = 7/114 (6%)
Frame = -1
Query: 256 FLEEAQIMKKLKHDKLVQLYAVVSEEP-IYIVTEYMNKGSLLDFLKDGEGRALKLPNLVD 314
F E +I+ +L H ++Q+++++ P I+I Y KG +L +K +D
Sbjct: 339 FPRELEILTRLDHPNIIQIHSILQRGPKIFIFMRYAEKGDMLSHIKK--------TGPID 184
Query: 315 MAA------QVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIED 362
A Q+A + Y+ + HRDL+ NIL+ L KIADFG AR D
Sbjct: 183 EAQTKVWFFQMAKALQYLHSHDIAHRDLKCENILLSKRLNVKIADFGFARYCRD 22
>14126
Length = 1265
Score = 60.1 bits (144), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 50/200 (25%), Positives = 93/200 (46%), Gaps = 11/200 (5%)
Frame = +3
Query: 253 PESFLEEAQIMKKLK---HDKLVQLYAVV------SEEPIYIVTEYMNKGSLLDFLKDGE 303
P + E ++K+L+ H +V+L V E + +V EY+ + L +L
Sbjct: 321 PMMAIREISMLKQLEQYEHPNVVRLLDVSHNTITDREIRLNLVFEYI-EHDLATYLAKCP 497
Query: 304 GRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDN 363
L + D+ Q+ G+ ++ +HRDL+ N+L+ K+ADFGLAR+ +
Sbjct: 498 SPGLGPDRIKDLMLQLLNGVDFLHSNRIVHRDLKPQNLLISKDGRLKLADFGLARIY--S 671
Query: 364 EYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQ 423
+ A + + +PE + + D+WS G + EL T+ R + G + + L++
Sbjct: 672 FHMALTTVVVTLWYRSPEVLMQAEYGTSVDIWSCGCIFAELFTR-RALFKGSSEFDQLKK 848
Query: 424 VERGYRMPCPQDCP--ISLH 441
+ +P D P +S+H
Sbjct: 849 IFEVIGLPPAGDWPEGVSVH 908
>00300
Length = 2318
Score = 59.3 bits (142), Expect = 4e-09, Method: Compositional matrix adjust.
Identities = 52/227 (22%), Positives = 105/227 (46%), Gaps = 12/227 (5%)
Frame = -1
Query: 256 FLEEAQIMKKLKHDKLVQLYAV-VSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPN--L 312
+E +I + ++H+ LV+ Y V V ++ + + EY + G++ + K G LP +
Sbjct: 1520 MCDEIKIFEGIQHENLVKYYGVEVHKDEMLMFMEYCDTGTIEEAAKMG------LPEYLI 1359
Query: 313 VDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDN-----EYTA 367
++ + ++ + +HRD++ ANI + + K+ DFG + ++ + E+
Sbjct: 1358 RRYTREIVLAVNHLHENSIVHRDIKGANIFLTSNGHVKLGDFGCSVKLKSHTTMPGEFHN 1179
Query: 368 RQGAK---FPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGM-NNREVLEQ 423
G P +T + YGR +D+WS G ++ E+ T G+ P+ + NN +++ +
Sbjct: 1178 LVGTTAYMAPEVFTQNDQGGYGR---AADIWSLGCVVIEMAT-GKRPWHDLDNNYQIMYK 1011
Query: 424 VERGYRMPCPQDCPISLHELMIHCWKKDPEERPTFEYLQSFLEDYFT 470
V G++ P + + DP +R L L+ FT
Sbjct: 1010 VGIGHKPAVPDSLSVEGKHFLDLIMCHDPAQRALASQL---LDHTFT 879
>11228
Length = 2155
Score = 58.5 bits (140), Expect = 6e-09, Method: Compositional matrix adjust.
Identities = 41/149 (27%), Positives = 75/149 (50%), Gaps = 5/149 (3%)
Frame = -2
Query: 88 VALYDYEARTE-DDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYVAPVDS--- 143
VA+ Y T+ D+LSF KG+ F + N E W T E+G +P+ +V +D
Sbjct: 1662 VAMLSYRKATDSDELSFCKGDVFVVQNEMEDGWLWVTCERTKESGLVPAPFVKDLDGDYE 1483
Query: 144 -IQAEEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDWDDMKGDHVKH 202
+++ ++ L +++A +L+ G G+FL+R+SE G YSL D V+
Sbjct: 1482 PVESLPYFHSCLSKEEAVEKLMLAGE--GSFLVRQSENYPGDYSLFFLCEKD-----VRR 1324
Query: 203 YKIRKLDNGGYYITTRAQFETLQQLVQHY 231
++I + G ++ F++L +++ Y
Sbjct: 1323 FRIER--RGNQFLVGGRLFDSLDGVIKRY 1243
Score = 37.0 bits (84), Expect = 0.016, Method: Compositional matrix adjust.
Identities = 22/57 (38%), Positives = 31/57 (54%)
Frame = -1
Query: 132 YIPSNYVAPVDSIQAEEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLS 188
+I S AP + WY G+LGR AE L G++L+RESE+ G++ LS
Sbjct: 2011 HINSALTAPDQKL----WYHGRLGRAGAEELLRD--QDAGSYLVRESESKLGSFVLS 1859
>00392
Length = 668
Score = 58.5 bits (140), Expect = 6e-09, Method: Compositional matrix adjust.
Identities = 53/174 (30%), Positives = 88/174 (50%), Gaps = 10/174 (5%)
Frame = +3
Query: 254 ESFLEEAQIMKKLKHDKLVQLYAVVSE------EPIYIVTEYMNKGSLLDFLKDGEGRAL 307
+ F EEA+++K+L+H +V+ + E + I +VTE M G+L +LK + +
Sbjct: 66 QRFKEEAEMLKELQHPNIVRFFDYWEEHNHRNRKVIILVTELMTSGTLKTYLKRFKKPNV 245
Query: 308 KLPNLVDMAAQVAAGMAYIERMN--YIHRDLRSANILV-GNGLICKIADFGLARLIEDNE 364
K+ L + QV G+ ++ IHRDL+ NI + G KI D GLA L N+
Sbjct: 246 KI--LKNWCRQVLKGLYFLHTRTPPVIHRDLKCDNIFITGPTGSVKIGDLGLATL--KNQ 413
Query: 365 YTARQGAKFPIKWTAPEAALY-GRFTIKSDVWSFGILLTELVTKGRVPYPGMNN 417
A+ P ++ APE +Y + DV++FG+ + E+ + PY +N
Sbjct: 414 SFAKSVIGTP-EFMAPE--MYEEHYDEAVDVYAFGMCMLEMAS-SEYPYSECSN 563
>01966
Length = 1735
Score = 58.2 bits (139), Expect = 7e-09, Method: Compositional matrix adjust.
Identities = 32/107 (29%), Positives = 58/107 (54%), Gaps = 1/107 (0%)
Frame = -1
Query: 253 PESFLEEAQIMKKLKHDKLVQLYAVVSE-EPIYIVTEYMNKGSLLDFLKDGEGRALKLPN 311
P S + E ++++L+H +V L V+ E E +++V E+++ + K EG L
Sbjct: 1582 PSSAIREIAMLRELRHTNIVCLEDVIMEDERLFLVFEFLSMDLKMYIDKFPEGVVLDRRL 1403
Query: 312 LVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLAR 358
+ Q+ G+ + + +HRDL+ N+L+ + KIADFG+AR
Sbjct: 1402 VKSYVFQIVTGINFCHQRRIVHRDLKPQNLLINHTGAIKIADFGMAR 1262
>07836
Length = 1478
Score = 57.0 bits (136), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 62/217 (28%), Positives = 100/217 (46%), Gaps = 42/217 (19%)
Frame = -1
Query: 283 IYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIE--------RMNYIHR 334
++++T+Y GSL D+L R L ++ +A G+A++ + HR
Sbjct: 1328 LFLITDYHENGSLHDYLL---SRVLDSSEMLALAHSAICGLAHLHIEIFGTRGKPAIAHR 1158
Query: 335 DLRSANILVGNGLICKIADFGLA-RLI-EDNEYTA----RQGAKFPIKWTAPEAALYGRF 388
D++S NILV C IAD GLA R I E NE RQG K ++ APE L
Sbjct: 1157 DIKSKNILVKKNGTCCIADLGLAVRYISESNEVDVAPNPRQGTK---RYMAPE-VLEMLL 990
Query: 389 TIK-------SDVWSFGILLTEL----VTKG-----RVPY-------PGMNNREVLEQVE 425
+K +D+++FG+++ E+ V G +VP+ P + ++ V+
Sbjct: 989 NVKNFDAFKQADMYAFGLVMWEIARCCVIGGVAEEYQVPFYNCLPHDPSFEDVRLVVSVD 810
Query: 426 RGYRMPCP---QDCPI--SLHELMIHCWKKDPEERPT 457
+ R P Q+ PI + ++M CW +P R T
Sbjct: 809 K-VRPDIPLRWQEDPIMKVMVKVMCECWSGNPAARLT 702
>31885
Length = 529
Score = 57.0 bits (136), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 46/169 (27%), Positives = 78/169 (46%), Gaps = 6/169 (3%)
Frame = -2
Query: 260 AQIMKKLKHDKLVQL-YAVVSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQ 318
++ +L H LV L YA EE +++V + G L ++ + + + + Q
Sbjct: 519 VDMLTRLDHPFLVNLWYAFQDEEDLFMVVDLFLGGDLRYHMQ--QEVSFREDCVKFYLCQ 346
Query: 319 VAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWT 378
+A + Y+ +HRD++ NIL+ C + DF +A +ED+E P +
Sbjct: 345 LALVLDYLRSQKIVHRDIKPDNILLDEQGHCHVTDFNIATQLEDDELATSTSGTRP--YM 172
Query: 379 APE---AALYGR--FTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLE 422
APE A+ R + D WS G+ L EL+ K R P+ +N + E
Sbjct: 171 APEVYGVAINERRGYGFPVDWWSLGVSLFELLKKRR-PFSVHSNTSLHE 28
>13066
Length = 551
Score = 55.8 bits (133), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 46/178 (25%), Positives = 79/178 (44%), Gaps = 12/178 (6%)
Frame = +3
Query: 233 GTWNG----NTKVAIKTL----KPGTMSPESFLEEAQIMKKLKHDKLVQLYAVVSEEPI- 283
GT+N N K+A K + P + F E ++ KL H ++Q+++++ P
Sbjct: 24 GTFNDGYGRNIKLACKIIDKEKAPVDFVEKFFPRELDLLTKLDHPYIIQIHSILQRXPKN 203
Query: 284 YIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILV 343
+I + +G LL +++ E +K Q+ + Y+ + HRDL+ NIL+
Sbjct: 204 FIFMRFAERGDLLTYIQ--EVGFVKEKQAKIWFYQMTTALNYLHSYDVAHRDLKCENILL 377
Query: 344 GNGLICKIADFGL--ARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIK-SDVWSFG 398
+ K+ADFG A + E E + + APE + K +D WS G
Sbjct: 378 SSHFNVKLADFGFACACITESGEKYMSRTYCGSAAYAAPEIVYGAPYAPKVADAWSLG 551
>12672
Length = 773
Score = 53.5 bits (127), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 40/164 (24%), Positives = 74/164 (45%), Gaps = 16/164 (9%)
Frame = +3
Query: 320 AAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPI---K 376
A+G+ Y+ ++HRD+++ANIL+ + K+ DF E Q A I
Sbjct: 21 ASGIQYLNDNGHVHRDIKTANILLDSEYTAKVGDFATVVSAPSGEGKTVQNASVVIGTAA 200
Query: 377 WTAPEAALYGRFTIKSDVWSFGILLTELVT----------KGRVPYPGMNNREVLEQVER 426
+ APE A++ + K D +SFG++L E++T + + M N E E++
Sbjct: 201 YLAPE-AIHFDVSTKLDSYSFGVVLLEVITGLVAQDYSREERTLSSHIMENVEEPEEIHD 377
Query: 427 GYRMPC---PQDCPISLHELMIHCWKKDPEERPTFEYLQSFLED 467
P L+++ + C ++RP + ++ LE+
Sbjct: 378 FVDQSAGTWPDGAVDKLYDISMRCLNLSKKQRPNVKDIRPELEE 509
>13212
Length = 1067
Score = 52.8 bits (125), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 45/167 (26%), Positives = 76/167 (45%), Gaps = 11/167 (6%)
Frame = -1
Query: 318 QVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKF---P 374
++ + ++ R + IHRD+++ N+L+ K+ADFG++ N T ++ F P
Sbjct: 956 EMCMALDFLHRHHVIHRDIKAGNVLLTIDGEVKLADFGVSA---KNTQTQQKRDTFIGTP 786
Query: 375 IKWTAPEAALY-----GRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERG-- 427
W APE L + K+D+WS G+ L E + P M+ VL ++ +
Sbjct: 785 Y-WMAPEVVLCETLKDTPYDFKADIWSLGVTLIEFA-QIEPPNKEMHPMRVLIKIHKSDP 612
Query: 428 YRMPCPQDCPISLHELMIHCWKKDPEERPT-FEYLQSFLEDYFTATE 473
+ P+ + + C KDP RPT E L+ TAT+
Sbjct: 611 PTLEKPKKWTKLFKDFIAKCLVKDPNLRPTAAELLEHPFMKRATATD 471
>09606
Length = 1300
Score = 52.4 bits (124), Expect = 4e-07, Method: Compositional matrix adjust.
Identities = 41/177 (23%), Positives = 76/177 (42%), Gaps = 22/177 (12%)
Frame = -3
Query: 260 AQIMKKLKHDKLVQLYA-VVSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQ 318
++ + H +VQ + + +++V E GSL D L + L ++ D
Sbjct: 980 VRMTHDISHPNVVQFHEWYETSNHLWLVVELCTGGSLADIL--AQDHHLPETSIRDFGIH 807
Query: 319 VAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYT-----ARQGAKF 373
+ G+ YI + + DLR + +L+ + K ADFGL+++ +N A G ++
Sbjct: 806 LVTGLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQW 627
Query: 374 PIK----------------WTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPG 414
I+ + APE +I SD+W+ G + E+ + G P+ G
Sbjct: 626 NIQSAEEMMKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFS-GHPPFLG 459
>04138
Length = 800
Score = 52.4 bits (124), Expect = 4e-07, Method: Compositional matrix adjust.
Identities = 32/93 (34%), Positives = 47/93 (50%), Gaps = 7/93 (7%)
Frame = +1
Query: 325 YIERMNYIHRDLRSANILVGNGLICKIADFGLAR-----LIEDNEYTARQGAKFPIKWTA 379
YI R +HRD+++ANIL+ + K+ADFGLAR L + N YT R W
Sbjct: 58 YIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNR----VVTLWYR 225
Query: 380 PEAALYG--RFTIKSDVWSFGILLTELVTKGRV 410
P L G ++ D W G ++ E+ T+ +
Sbjct: 226 PPELLLGDRNYSTAIDQWGAGCIMAEMWTRNPI 324
>21079
Length = 878
Score = 51.2 bits (121), Expect = 8e-07, Method: Compositional matrix adjust.
Identities = 39/143 (27%), Positives = 69/143 (48%), Gaps = 4/143 (2%)
Frame = +1
Query: 268 HDKLVQLY-AVVSEEPIYIVTEYMNKGSLLD-FLKDGEGRALKLPNLVDMAAQVAAGMAY 325
H KL+ L+ A + + +V E++ G L + ++D L + V Q+ +G+ Y
Sbjct: 1 HPKLLMLWDAFEAPRTMVLVMEFVGAGELFERVIRDD--FVLTERDCVHFVRQICSGVGY 174
Query: 326 IERMNYIHRDLRSANILV--GNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAA 383
+ + +H DL+ N+L N KI DFGLAR + + + Q ++ APE
Sbjct: 175 MHTQSILHLDLKPENVLCVSDNSNQIKIIDFGLARFYKPGD--SLQVLFGTPEFIAPEVV 348
Query: 384 LYGRFTIKSDVWSFGILLTELVT 406
Y +D+WS G++ L++
Sbjct: 349 NYDEINFTTDMWSIGVICYILLS 417
>29243
Length = 1147
Score = 51.2 bits (121), Expect = 9e-07, Method: Compositional matrix adjust.
Identities = 32/98 (32%), Positives = 51/98 (52%), Gaps = 2/98 (2%)
Frame = +2
Query: 136 NYVAPVDSIQAEEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETT--KGAYSLSIRDWD 193
+YV S+++ WY G + R A++ L + P GTFLIR + +G SLSI+
Sbjct: 269 DYVNEPCSLESYNWYVGIMERPVAQKXLDTC--PDGTFLIRVTNNPLRRGELSLSIK--- 433
Query: 194 DMKGDHVKHYKIRKLDNGGYYITTRAQFETLQQLVQHY 231
+ V+H K+ + G +Y+ F+ +Q LV HY
Sbjct: 434 --YANAVRHIKVNRNPQGRFYLADGRYFDNIQSLVDHY 541
Score = 40.4 bits (93), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 20/53 (37%), Positives = 28/53 (52%), Gaps = 2/53 (3%)
Frame = +2
Query: 88 VALYDYEARTEDDLSFHKGEKFQIL--NSSEGDWWEARSLTTGETGYIPSNYV 138
VA+YDY A + LS ++ IL N + WW+ +L T + GY P YV
Sbjct: 641 VAVYDYAATSTSQLSMKLNDRIAILSKNGQDKGWWKGENLRTQKIGYFPLAYV 799
>12324
Length = 946
Score = 48.9 bits (115), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 22/53 (41%), Positives = 32/53 (60%)
Frame = +3
Query: 88 VALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYVAP 140
VA+YDYEA +D+L+F + ++ ++ WWE + G TG PSNYV P
Sbjct: 699 VAIYDYEAEKDDELTFSENSVIYVIRKNDDGWWEG--VMDGVTGLFPSNYVEP 851
>19094
Length = 898
Score = 48.5 bits (114), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 28/83 (33%), Positives = 41/83 (49%)
Frame = +1
Query: 322 GMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPE 381
G+ Y+ IHRD+++ NIL+ N K+ADFG+A + D P W APE
Sbjct: 94 GL*YLHSRRKIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTP-YWMAPE 270
Query: 382 AALYGRFTIKSDVWSFGILLTEL 404
+ +D+WS GI E+
Sbjct: 271 VIQEIGYDCVADIWSLGITALEM 339
>30755
Length = 1137
Score = 47.8 bits (112), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 37/142 (26%), Positives = 66/142 (46%), Gaps = 2/142 (1%)
Frame = +2
Query: 316 AAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEY--TARQGAKF 373
A++ + + Y+ I+RDL+ N+L+ K+ADFGL + ED Y T +
Sbjct: 50 GAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCK--EDITYGRTTKTFCGT 223
Query: 374 PIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCP 433
P ++ APE + D W G+++ E++ GR+P+ + +VL + + P
Sbjct: 224 P-EYLAPEVLDDNDYGRAVDWWGTGVVMYEMIC-GRLPFYN-RDHDVLFTLILVEDVKFP 394
Query: 434 QDCPISLHELMIHCWKKDPEER 455
++ L+ KDP R
Sbjct: 395 RNITDEAKSLLSGLLAKDPRNR 460
>15910
Length = 1361
Score = 47.8 bits (112), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 34/114 (29%), Positives = 57/114 (50%), Gaps = 3/114 (2%)
Frame = +2
Query: 317 AQVAAGMAYIERMNYIHRDLRSANIL---VGNGLICKIADFGLARLIEDNEYTARQGAKF 373
+ + G+ YI +HRDL+ N+L + + K+ADFGL+R+IE E
Sbjct: 485 SDILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLADFGLSRIIEP-EVQMSTVCGT 661
Query: 374 PIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERG 427
P + APE ++T D+WS G++ L+ G P+ N E+ ++ +G
Sbjct: 662 P-GYCAPEVLKGDKYTPSVDMWSVGVIAYILLC-GYEPFFAENEFEMYRKIIKG 817
>26560
Length = 398
Score = 46.2 bits (108), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 32/103 (31%), Positives = 52/103 (50%), Gaps = 1/103 (0%)
Frame = -1
Query: 316 AAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPI 375
AA+V G+ ++ ++RDL+ ANIL+ +I+D GLA A G
Sbjct: 338 AAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGLACDFSKKRPHASVGTH--- 168
Query: 376 KWTAPEAALYGR-FTIKSDVWSFGILLTELVTKGRVPYPGMNN 417
+ APE + G+ + +D +SFG +L +L+ KG P+ N
Sbjct: 167 GYMAPEVLMKGQSYDSSADWFSFGCMLYKLL-KGHSPFRQHNQ 42
>03240
Length = 1683
Score = 46.2 bits (108), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 37/138 (26%), Positives = 65/138 (47%), Gaps = 8/138 (5%)
Frame = -3
Query: 242 AIKTLKPGTMSPESFLE----EAQIMKKLKHDKLVQLYAVVSEEP-IYIVTEYMNKGSLL 296
A+KTL+ + + + E I+ + ++ +V+LY + +Y V +Y+ G L+
Sbjct: 1204 AMKTLRKSDVLKRNQVAHVKAERDILAEADNEWVVKLYYSFQDHNYLYFVMDYVPGGDLM 1025
Query: 297 DFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGL 356
L E L P A++ + + RM +IHRD++ NIL+ K+ DFGL
Sbjct: 1024 GLLIRME--ILDEPLARFYVAELVQAIESVHRMGFIHRDIKPDNILIDRNGHIKLTDFGL 851
Query: 357 A---RLIEDNEYTARQGA 371
R +++Y R G
Sbjct: 850 CTGFRWTHNSKYYQRDGT 797
>21210
Length = 518
Score = 45.4 bits (106), Expect = 4e-05, Method: Compositional matrix adjust.
Identities = 34/86 (39%), Positives = 47/86 (54%), Gaps = 4/86 (4%)
Frame = +3
Query: 380 PEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPG-MNNREVLEQVERGYRMPC-PQDCP 437
P A+ +G + ++SDVWS GI L EL T GR PY ++ + L+QV RG PC P D
Sbjct: 42 PRASSHG-YDVRSDVWSLGITLMELAT-GRFPYRKWVSIFDQLQQVVRGV-APCLPHDGA 212
Query: 438 IS--LHELMIHCWKKDPEERPTFEYL 461
S + C KD ++RP + L
Sbjct: 213 FSHDFVNFVNKCLTKDEKQRPKYNKL 290
>29687
Length = 434
Score = 45.1 bits (105), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 22/55 (40%), Positives = 32/55 (58%)
Frame = -2
Query: 89 ALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYVAPVDS 143
AL+DY A+ ED+LSF KG ++ +G WW T + + PSNYV +D+
Sbjct: 286 ALHDYNAKREDELSFCKGAIITNVSRQDGGWWRG-DYGTKKQHWFPSNYVEEIDT 125
>19761
Length = 473
Score = 44.7 bits (104), Expect = 8e-05, Method: Compositional matrix adjust.
Identities = 34/119 (28%), Positives = 54/119 (45%), Gaps = 3/119 (2%)
Frame = -3
Query: 318 QVAAGMAYIERMN--YIHRDLRSANILVGNGLICKIADFGLAR-LIEDNEYTARQGAKFP 374
Q A+ + Y+ +HRDL+ NI V ++ D GLAR L ++ Q
Sbjct: 399 QTASALNYMHTHTPVILHRDLKPQNIYVTEKGDVRLGDLGLARKLTGPADFATSQVGT-- 226
Query: 375 IKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCP 433
I + +PE + KSD+WS G + ++ G+ M +L QV G ++P P
Sbjct: 225 IMYLSPEILSQQPYNSKSDIWSLGCVFYDIT--GKKGSDEMGVMFLLVQVMGGRKLPLP 55
>11185
Length = 473
Score = 44.3 bits (103), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 35/142 (24%), Positives = 61/142 (42%), Gaps = 25/142 (17%)
Frame = +1
Query: 314 DMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYT-----AR 368
D + G+ YI + + DLR + +L+ + K ADFGL+++ +N A
Sbjct: 13 DFGIHLVTGLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAE 192
Query: 369 QGAKFPIK----------------WTAPEAALYGRFTIKSDVWSFGILLTELVTKGRV-- 410
G ++ I+ + APE +I SD+W+ G + E+ + R+
Sbjct: 193 AGDQWNIQSAEEMMKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSGSRLSA 372
Query: 411 -PYPG-MNNREVLEQVERGYRM 430
P P +N E L Q + R+
Sbjct: 373 KPSPEFLNLLESLLQKDSTRRL 438
>14257
Length = 919
Score = 42.4 bits (98), Expect = 5e-04, Method: Compositional matrix adjust.
Identities = 27/85 (31%), Positives = 45/85 (52%)
Frame = -3
Query: 147 EEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDWDDMKGDHVKHYKIR 206
EEWY GK+GRK+AE+ L G FL+RE+ + + LS R + +V+H +
Sbjct: 896 EEWYHGKIGRKEAEKLL----ELDGDFLVREASNSAAQFVLSGR-----QNGNVRHLLL- 747
Query: 207 KLDNGGYYITTRAQFETLQQLVQHY 231
+D G T F+++ L+ ++
Sbjct: 746 -VDPDGIVRTKDFIFDSVSHLINYH 675
>28638
Length = 1458
Score = 42.0 bits (97), Expect = 5e-04, Method: Compositional matrix adjust.
Identities = 35/109 (32%), Positives = 53/109 (48%), Gaps = 5/109 (4%)
Frame = -1
Query: 303 EGRALKLPNLVDMAAQVAAGMAYIE--RMNYIHRDLRSANILVGN---GLICKIADFGLA 357
EG +L L A Q+ + ++ MN IH DL+ NIL+ N I KI DFG +
Sbjct: 852 EGVSLNLTR--KFAQQLCTALLFLATPEMNIIHCDLKPENILLCNPKRSAI-KIVDFGSS 682
Query: 358 RLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVT 406
+ Y Q ++F + +PE L + + D+WS G +L E+ T
Sbjct: 681 CQLGQRIYQYIQ-SRF---YRSPEVLLGVPYDLAIDMWSLGCILVEMHT 547
>28095
Length = 597
Score = 41.6 bits (96), Expect = 7e-04, Method: Compositional matrix adjust.
Identities = 19/50 (38%), Positives = 28/50 (56%)
Frame = +3
Query: 89 ALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYV 138
A+YDY+A D++SF+ G+ + W R TG+ G +PSNYV
Sbjct: 270 AMYDYQAADSDEVSFNDGDTIIECQPVDAGWMTGRVERTGQYGMLPSNYV 419
>12786
Length = 460
Score = 41.2 bits (95), Expect = 9e-04, Method: Compositional matrix adjust.
Identities = 27/107 (25%), Positives = 51/107 (47%), Gaps = 21/107 (19%)
Frame = -3
Query: 332 IHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPI-KWTAPEAALYG---- 386
IH DL+ AN ++ G + K+ DFG+A ++ ++ + + ++ + +PEA +
Sbjct: 344 IHSDLKPANFMLVAGNL-KLIDFGIANTLQQDKTSVLKDSRVGTPSYMSPEAIMAACDDS 168
Query: 387 ----------------RFTIKSDVWSFGILLTELVTKGRVPYPGMNN 417
+ ++SDVWS G +L +V GR P+ + N
Sbjct: 167 ADDSMEEDGHRTKPKYKVGVRSDVWSLGCILYNMVY-GRTPFQHIKN 30
>26711
Length = 405
Score = 41.2 bits (95), Expect = 0.001, Method: Composition-based stats.
Identities = 31/111 (27%), Positives = 54/111 (48%), Gaps = 3/111 (2%)
Frame = -2
Query: 318 QVAAGMAYIERMNYIHRDLRSANILVGNGLI--CKIADFGLAR-LIEDNEYTARQGAKFP 374
QV + ++ +H DL+ +N+L+ + ++ DFGLAR L E G
Sbjct: 392 QVLDILQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARKLYPPQETFLNHGTP-- 219
Query: 375 IKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVE 425
+T+PEA + SDVW G+L L++ G+ P+ + E L++ +
Sbjct: 218 -GFTSPEALDVKPISTASDVWGVGVLAYILLS-GQSPFQADSATESLKKTQ 72
>05206
Length = 1075
Score = 41.2 bits (95), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 19/50 (38%), Positives = 27/50 (54%)
Frame = +1
Query: 89 ALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYV 138
ALY +EA E + + E+ QIL +GD W G G++PS+YV
Sbjct: 103 ALYPFEAMNEGSVPMGENEEMQILEEDQGDGWTRVRKADGSEGFVPSSYV 252
>01494
Length = 2122
Score = 40.8 bits (94), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 30/107 (28%), Positives = 49/107 (45%), Gaps = 5/107 (4%)
Frame = +3
Query: 89 ALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYVAPVDS---IQ 145
AL+DY A +D+LSF KG ++ +G WW + + PSN+V +++ +
Sbjct: 318 ALHDYNANRDDELSFCKGAIITNVSRQDGGWWRG-DYGAKKQHWFPSNFVEEIETHSDVN 494
Query: 146 AEEWYFGKL--GRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIR 190
++ G L G D + L+ PRG K A+ +S R
Sbjct: 495 SDSMPLGSLQQGSFDIQGCLVEPLAPRG---------DKSAFRISTR 608
>37602
Length = 804
Score = 40.8 bits (94), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 23/77 (29%), Positives = 37/77 (48%)
Frame = -1
Query: 278 VSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLR 337
+ E ++I EY GS+ D L P + + + G+ Y+ R +HRD++
Sbjct: 309 LRREKLWIAMEYCGGGSMQDIYH--VTGPLTEPQIAFVCRETLKGLHYLHRRGKMHRDIK 136
Query: 338 SANILVGNGLICKIADF 354
ANIL+ K+ADF
Sbjct: 135 GANILLTEEGDVKLADF 85
>32000
Length = 644
Score = 40.0 bits (92), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 29/85 (34%), Positives = 45/85 (52%), Gaps = 3/85 (3%)
Frame = -1
Query: 350 KIADFGLARL--IEDNEYTARQGAKFPIKWTAPEAALYGRF-TIKSDVWSFGILLTELVT 406
KIADFGLAR+ + YT + + APE L RF ++ D+WS G + E++T
Sbjct: 569 KIADFGLARVFGLPVRTYTHEV---ITLWYRAPEILLGCRFYSVPVDIWSLGCIFVEMMT 399
Query: 407 KGRVPYPGMNNREVLEQVERGYRMP 431
+ R +PG + + L ++ R P
Sbjct: 398 R-RALFPGDSEIDQLYRIFRTLGTP 327
>18481
Length = 437
Score = 39.7 bits (91), Expect = 0.003, Method: Composition-based stats.
Identities = 21/65 (32%), Positives = 37/65 (56%), Gaps = 3/65 (4%)
Frame = -1
Query: 305 RALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICK---IADFGLARLIE 361
R L ++ ++ Q+ + + +I + +IHRDL+ N L+G G C I DFGL++ +
Sbjct: 212 RRFTLKTILMVSDQLLSRLEFIHQKCFIHRDLKPDNFLMGLGRHCHRLYIIDFGLSKRYK 33
Query: 362 DNEYT 366
D + T
Sbjct: 32 DTQGT 18
>32264
Length = 287
Score = 39.3 bits (90), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 18/44 (40%), Positives = 29/44 (65%)
Frame = +1
Query: 424 VERGYRMPCPQDCPISLHELMIHCWKKDPEERPTFEYLQSFLED 467
+E GYR+ P S+++LM+ CW+ PE+RP F+ L + L+D
Sbjct: 1 IEDGYRLQQNPQTPDSVYKLMLRCWEYVPEKRPHFKELYTSLKD 132
>35671
Length = 567
Score = 38.5 bits (88), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 15/47 (31%), Positives = 28/47 (59%)
Frame = -3
Query: 425 ERGYRMPCPQDCPISLHELMIHCWKKDPEERPTFEYLQSFLEDYFTA 471
++G R+ P C +++M+ CW + EERPTF+ L +E+ + +
Sbjct: 565 QKGNRLAKPISCTDEAYKVMLQCWTESREERPTFKKLVPVMENLYRS 425
>16716
Length = 934
Score = 37.7 bits (86), Expect = 0.010, Method: Compositional matrix adjust.
Identities = 28/111 (25%), Positives = 44/111 (39%)
Frame = -1
Query: 28 YRYGTDPTPQHYPSFGVTSIPNYNNFHAAGGQGLTVFGGVNSSSHXXXXXXXXXXXXXXF 87
Y +P PQH P + + A Q GG +++
Sbjct: 577 YEVSEEPAPQHEPEESPYEMADEEPAAPAQSQP----GGGSTA----------------- 461
Query: 88 VALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYV 138
+ALYDY+A +D+L+F + + + WW R G+ G P+NYV
Sbjct: 460 IALYDYQAADDDELTFDPDDVITDIEMIDDGWW--RGSCHGKNGLFPANYV 314
>17286
Length = 489
Score = 37.7 bits (86), Expect = 0.011, Method: Compositional matrix adjust.
Identities = 17/56 (30%), Positives = 31/56 (55%)
Frame = +3
Query: 89 ALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYVAPVDSI 144
A+YD+ ++ +L F +G+ +++ + +W+E G+ GY P NYV V I
Sbjct: 36 AIYDFLPESDGELGFQEGDMITLISQVDENWFEGS--VHGKVGYFPINYVEVVVPI 197
>16708
Length = 1397
Score = 37.7 bits (86), Expect = 0.012, Method: Compositional matrix adjust.
Identities = 14/45 (31%), Positives = 27/45 (60%)
Frame = -1
Query: 315 MAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARL 359
+A Q + +I + +H D+++ N+LV CK+ D+G+A+L
Sbjct: 1079 IAGQXVCALEHIHELGVVHMDVKADNVLVDAHGNCKLTDYGIAQL 945
>30740
Length = 488
Score = 37.4 bits (85), Expect = 0.014, Method: Compositional matrix adjust.
Identities = 13/33 (39%), Positives = 21/33 (63%)
Frame = +2
Query: 91 YDYEARTEDDLSFHKGEKFQILNSSEGDWWEAR 123
YD+ R +DL F KG+ ++++ E +WW AR
Sbjct: 203 YDFSGRDPEDLPFSKGDILELISKDEEEWWTAR 301
>27405
Length = 532
Score = 37.0 bits (84), Expect = 0.017, Method: Compositional matrix adjust.
Identities = 32/121 (26%), Positives = 52/121 (42%)
Frame = -3
Query: 275 YAVVSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHR 334
YA + E + + + MN G L L + + AA+V G+ ++ ++R
Sbjct: 353 YAFQTPEKLCFILDLMNGGDLHYHLS--QHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYR 180
Query: 335 DLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDV 394
DL+ ANIL+ +I+D GLA + A G + APE + G+ S
Sbjct: 179 DLKPANILLDENGHVRISDLGLACDFSKKKPHASVGTH---GYMAPEVLMKGQAYDSSAD 9
Query: 395 W 395
W
Sbjct: 8 W 6
>38046
Length = 446
Score = 36.6 bits (83), Expect = 0.020, Method: Composition-based stats.
Identities = 15/26 (57%), Positives = 20/26 (76%)
Frame = -1
Query: 319 VAAGMAYIERMNYIHRDLRSANILVG 344
+A MAY+E+ N+IHR+L NILVG
Sbjct: 98 IADAMAYMEKENFIHRNLGDRNILVG 21
>06462
Length = 1511
Score = 36.2 bits (82), Expect = 0.033, Method: Compositional matrix adjust.
Identities = 27/99 (27%), Positives = 43/99 (43%)
Frame = +1
Query: 133 IPSNYVAPVDSIQAEEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDW 192
+PS+ D E WY GK+ R++AE+ L G FL+RES + LS +
Sbjct: 1048 MPSSETGVTDPPLHELWYHGKMSRREAEKLL----GKDGDFLVRESGHNXSQFVLSGK-- 1209
Query: 193 DDMKGDHVKHYKIRKLDNGGYYITTRAQFETLQQLVQHY 231
H + + +D G T F+ + LV ++
Sbjct: 1210 -----HHGQFIHLLLVDPDGIVRTKDYIFDNISHLVSYH 1311
>21433
Length = 590
Score = 35.8 bits (81), Expect = 0.044, Method: Compositional matrix adjust.
Identities = 25/89 (28%), Positives = 40/89 (44%)
Frame = +2
Query: 318 QVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKW 377
Q+++ + Y IHRD++ N+L+G KIADFG + + T G + +
Sbjct: 191 QLSSALEYCHYRKVIHRDIKPENLLLGLKGDLKIADFGWSVHAPSSRRTTMCGT---LDY 361
Query: 378 TAPEAALYGRFTIKSDVWSFGILLTELVT 406
PE D+WS G+L E +
Sbjct: 362 LPPEMVEGKTHDENVDLWSLGVLCYEFLV 448
>01392
Length = 1806
Score = 35.4 bits (80), Expect = 0.049, Method: Compositional matrix adjust.
Identities = 32/109 (29%), Positives = 51/109 (46%), Gaps = 12/109 (11%)
Frame = -1
Query: 318 QVAAGMAYIERMNYIHRDLRSANIL---VGNGLICKIADFGLARLIE-DNEYTARQGAKF 373
+A + ++ HRDL+ NIL + + + KI DF LA I D + T
Sbjct: 1767 HIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGISCDGDGTKTPELLT 1588
Query: 374 PI---KWTAPEA--ALYG---RFTIKSDVWSFGILLTELVTKGRVPYPG 414
P+ ++ APE A G + + D+WS GI+L ++ G P+ G
Sbjct: 1587 PVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILYIMLC-GYPPFYG 1444
>07933
Length = 728
Score = 35.0 bits (79), Expect = 0.061, Method: Compositional matrix adjust.
Identities = 13/30 (43%), Positives = 18/30 (60%)
Frame = +3
Query: 433 PQDCPISLHELMIHCWKKDPEERPTFEYLQ 462
P CP L+ +M+ CW +P RPTF L+
Sbjct: 3 PNYCPNLLYNIMMQCWSAEPSARPTFHKLE 92
>18881
Length = 762
Score = 35.0 bits (79), Expect = 0.062, Method: Compositional matrix adjust.
Identities = 22/65 (33%), Positives = 34/65 (52%), Gaps = 2/65 (3%)
Frame = -3
Query: 169 PRGTFLIRESETTKGAYSLSIRDWDDMK--GDHVKHYKIRKLDNGGYYITTRAQFETLQQ 226
P GTFLIR + T S R+ + V+H K+ + G +Y+ F+++QQ
Sbjct: 748 PDGTFLIRVTNT-------SARESCPQY*YANAVRHIKVNRNPQGRFYLADGHYFDSVQQ 590
Query: 227 LVQHY 231
LV+HY
Sbjct: 589 LVEHY 575
Score = 28.9 bits (63), Expect = 5.2, Method: Compositional matrix adjust.
Identities = 14/45 (31%), Positives = 22/45 (48%), Gaps = 2/45 (4%)
Frame = -3
Query: 101 LSFHKGEKFQIL--NSSEGDWWEARSLTTGETGYIPSNYVAPVDS 143
++ ++ IL N + WW+ +L T + GY P YV DS
Sbjct: 436 VTLKLNDRISILSKNGQDKGWWKGENLRTKKVGYFPLAYVDEEDS 302
>13664
Length = 507
Score = 35.0 bits (79), Expect = 0.064, Method: Compositional matrix adjust.
Identities = 16/45 (35%), Positives = 25/45 (55%)
Frame = +2
Query: 88 VALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGY 132
VALYDY+A+ D+L+ G+ +L+ WW L G+ G+
Sbjct: 374 VALYDYKAQRSDELTILSGDVIMLLHKDSESWWMGE-LLDGQQGF 505
>31789
Length = 676
Score = 34.3 bits (77), Expect = 0.13, Method: Compositional matrix adjust.
Identities = 22/76 (28%), Positives = 40/76 (52%), Gaps = 6/76 (7%)
Frame = +2
Query: 254 ESFLEEAQIMKKLKHDKLVQLYAVVSE------EPIYIVTEYMNKGSLLDFLKDGEGRAL 307
+ F EEA+++K+L+H +V+ + E + I +VTE M G+L +LK + +
Sbjct: 452 QRFKEEAEMLKELQHPNIVRFFDYWEEHNHRNRKVIILVTELMTSGTLKTYLK--RFKKI 625
Query: 308 KLPNLVDMAAQVAAGM 323
L L + Q+ G+
Sbjct: 626 NLKVLKNWCRQILKGL 673
>02638
Length = 1490
Score = 33.9 bits (76), Expect = 0.14, Method: Compositional matrix adjust.
Identities = 25/103 (24%), Positives = 49/103 (47%), Gaps = 7/103 (6%)
Frame = +1
Query: 375 IKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRM---- 430
I + APE + DVWS G ++ E+ T R P+ N+ ++ + +++
Sbjct: 28 IAFMAPEVLRGESYGRACDVWSVGCVMIEMCT-CRPPW---NSHDISNHLALIFKIASSV 195
Query: 431 ---PCPQDCPISLHELMIHCWKKDPEERPTFEYLQSFLEDYFT 470
P P++ + +LM+ C ++D + RP+ + L + FT
Sbjct: 196 DPPPIPENMSPPVRDLMLRCLEQDSDFRPSAKDL--LMHPLFT 318
>29360
Length = 363
Score = 33.9 bits (76), Expect = 0.16, Method: Composition-based stats.
Identities = 28/116 (24%), Positives = 50/116 (43%), Gaps = 7/116 (6%)
Frame = +3
Query: 235 WNGNTK--VAIKTLKPGTMSPESFLEEAQIMKKLKHD-----KLVQLYAVVSEEPIYIVT 287
W T VAIK LK E I+++L + V+ + + +
Sbjct: 12 WKKGTSEIVAIKILKNHPSYARQGQIEVSILQRLSQESADDYNFVRAFECFQHKNHTCLV 191
Query: 288 EYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILV 343
M + +L DFLK + + L L + + QV + ++++ IH DL+ NI++
Sbjct: 192 FEMLEQNLYDFLKQNKFQPLPLKYIRPITQQVLTALRKLKQLGLIHADLKPENIML 359
>37260
Length = 401
Score = 33.5 bits (75), Expect = 0.18, Method: Composition-based stats.
Identities = 17/56 (30%), Positives = 30/56 (53%)
Frame = -1
Query: 149 WYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDWDDMKGDHVKHYK 204
WY+G L ++AE +L+ G+FL+R+S SLS + + ++H+K
Sbjct: 182 WYWGPLSYEEAESKLMD--KRDGSFLVRDSSNENYILSLSFKSMGHVHHTRIEHHK 21
>00394
Length = 548
Score = 32.0 bits (71), Expect = 0.55, Method: Compositional matrix adjust.
Identities = 18/53 (33%), Positives = 31/53 (58%), Gaps = 6/53 (11%)
Frame = -2
Query: 254 ESFLEEAQIMKKLKHDKLVQLYAVVSE------EPIYIVTEYMNKGSLLDFLK 300
+ F EEA+++K+L+H +V+ + E + I +VTE M G+L +LK
Sbjct: 166 QRFKEEAEMLKELQHPNIVRFFDYWEEHNHRNRKVIILVTELMTSGTLKTYLK 8
>18401
Length = 463
Score = 31.6 bits (70), Expect = 0.82, Method: Compositional matrix adjust.
Identities = 18/50 (36%), Positives = 27/50 (54%)
Frame = -3
Query: 377 WTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVER 426
+ APE L ++ DVWS G ++ EL T G + +N+E L +ER
Sbjct: 434 YRAPEVILELGWSHPCDVWSVGCIMFELYT-GYTLFQTHDNKEHLAMMER 288
>17516
Length = 453
Score = 31.2 bits (69), Expect = 0.87, Method: Compositional matrix adjust.
Identities = 28/101 (27%), Positives = 47/101 (46%), Gaps = 6/101 (5%)
Frame = -3
Query: 379 APEAALY-GRFTIKSDVWSFGILLTELVTKGRVPYPGMNNR---EVLEQVERGYRMPCPQ 434
APE L G++ +K+DV+S I+L EL G+ +++ + + V+ G R
Sbjct: 415 APEVLLQKGQYDMKADVYSLAIILWEL-WYGQDAADHISSHLFGRLEDAVQAGLRPSVTM 239
Query: 435 DC--PISLHELMIHCWKKDPEERPTFEYLQSFLEDYFTATE 473
C P +L+ W+ +RPT F ED+ T+
Sbjct: 238 TCKPPDDWLKLLQSGWEFHASKRPTSRDAAEFFEDFLERTK 116
>13641
Length = 2081
Score = 31.2 bits (69), Expect = 1.0, Method: Compositional matrix adjust.
Identities = 15/58 (25%), Positives = 28/58 (48%), Gaps = 9/58 (15%)
Frame = +2
Query: 89 ALYDYEARTEDD-------LSFHKGEKFQILNSSEGDWWEA--RSLTTGETGYIPSNY 137
A++ + ++ +D+ LSF +G+ I+N + WW+A G IPS +
Sbjct: 164 AMFSFNSKLDDNIPCKEAGLSFQQGDILHIVNQEDAIWWQAYKHGDAKKRAGLIPSRH 337
>27287
Length = 514
Score = 30.8 bits (68), Expect = 1.2, Method: Compositional matrix adjust.
Identities = 11/30 (36%), Positives = 19/30 (63%)
Frame = -2
Query: 443 LMIHCWKKDPEERPTFEYLQSFLEDYFTAT 472
+M CW++DP +RP+F L L+ T++
Sbjct: 474 IMHSCWQEDPNDRPSFSRLVQELDKMLTSS 385
>23319
Length = 2235
Score = 30.8 bits (68), Expect = 1.3, Method: Compositional matrix adjust.
Identities = 12/45 (26%), Positives = 24/45 (53%)
Frame = +3
Query: 380 PEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQV 424
P+ ++ D+WS G + EL GR +PG ++ + L+++
Sbjct: 3 PDVYXAKMYSTSIDMWSAGCIFAELANAGRPLFPGNDDDDQLKRI 137
>29590
Length = 320
Score = 30.4 bits (67), Expect = 1.9, Method: Composition-based stats.
Identities = 13/43 (30%), Positives = 26/43 (60%)
Frame = +3
Query: 377 WTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNRE 419
+ APE Y +I++D+WS G+L ++T P+ G+ +++
Sbjct: 72 YVAPEVLDYEPLSIQTDMWSLGVLSYVMLTACS-PFVGITSKK 197
>36481
Length = 806
Score = 29.6 bits (65), Expect = 2.5, Method: Compositional matrix adjust.
Identities = 26/108 (24%), Positives = 48/108 (44%), Gaps = 6/108 (5%)
Frame = +2
Query: 241 VAIKTLKPGTMSPESFLEEAQIMKKLK----HDK--LVQLYAVVSEEPIYIVTEYMNKGS 294
+A+K +K E+ E +++KL+ H K VQ+ ++ +M S
Sbjct: 446 IALKIIKNVDKYREAAKLEINVLEKLREKDPHAKHMCVQMLDWFDYHGHVCISFHMLGLS 625
Query: 295 LLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANIL 342
+ DFLKD A + + ++ Q+ + ++ H DL+ NIL
Sbjct: 626 VFDFLKDNSYGAYPIEQVRHISYQLCYAVNFLHENQLTHTDLKPENIL 769
>27562
Length = 399
Score = 29.3 bits (64), Expect = 3.3, Method: Composition-based stats.
Identities = 18/54 (33%), Positives = 26/54 (48%), Gaps = 3/54 (5%)
Frame = -1
Query: 418 REVLEQVERGYRMPCPQDCPISLHELMIH-CWKKDPEERPT--FEYLQSFLEDY 468
R + Q+ R P+ C SL E++ WKKDP ER E L F++ +
Sbjct: 222 RVLWTQMRRRGTQIQPRPCSSSLFEIL*ETAWKKDPSERTENDIEILMDFMQHF 61
>18050
Length = 448
Score = 28.5 bits (62), Expect = 6.4, Method: Composition-based stats.
Identities = 12/56 (21%), Positives = 24/56 (42%)
Frame = +3
Query: 88 VALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYVAPVDS 143
+A + YE+ D L G+ + W++ + G G+ P +Y ++S
Sbjct: 27 IAKHSYESDEPDVLQLELGDVVNVSRKLPDGWYQGERIRDGAVGWFPGSYTEELNS 194
>15741
Length = 402
Score = 28.5 bits (62), Expect = 7.0, Method: Composition-based stats.
Identities = 11/32 (34%), Positives = 18/32 (56%)
Frame = -3
Query: 311 NLVDMAAQVAAGMAYIERMNYIHRDLRSANIL 342
+ A VA GMA++ +HRD+ + N+L
Sbjct: 97 DFFSFALHVARGMAHVANNKIVHRDVAARNVL 2
>18663
Length = 600
Score = 28.1 bits (61), Expect = 7.2, Method: Compositional matrix adjust.
Identities = 20/65 (30%), Positives = 30/65 (46%), Gaps = 10/65 (15%)
Frame = +2
Query: 377 WTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPY--------PGMNNREVLEQV--ER 426
+ APE + D W+ G+LL E++ GR P+ P N + L QV E+
Sbjct: 26 YIAPEILRGEDYGFSVDWWALGVLLYEMLA-GRSPFDIAGASENPDQNTEDYLFQVILEK 202
Query: 427 GYRMP 431
R+P
Sbjct: 203 TIRIP 217
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000348295 | hsapiens_gene_ensembl | Proto-oncogene
tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn) (Protooncogene
Syn) (SLK). [Source:Uniprot/SWISSPROT;Acc:P06241]
(482 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
21808 318 5e-88
06405 249 1e-66
11780 147 3e-55
04852 148 6e-36
09007 142 2e-34
17300 123 2e-33
20640 124 6e-29
07291 122 3e-28
14116 117 9e-27
08294 104 8e-23
18996 99 6e-21
07940 97 1e-20
22005 82 3e-20
17637 93 3e-19
01718 86 3e-17
13592 82 4e-16
14477 80 2e-15
13305 80 3e-15
00715 77 2e-14
01756 73 2e-13
17253 72 4e-13
19301 70 2e-12
01707 69 6e-12
29581 67 2e-11
12721 66 2e-11
01060 66 2e-11
18484 63 2e-10
25550 63 2e-10
18921 63 3e-10
14420 62 5e-10
04591 61 9e-10
27546 61 1e-09
14126 60 2e-09
00300 59 4e-09
11228 59 6e-09
00392 59 6e-09
01966 58 7e-09
07836 57 2e-08
31885 57 2e-08
13066 56 3e-08
12672 54 2e-07
13212 53 3e-07
09606 52 4e-07
04138 52 4e-07
21079 51 8e-07
29243 51 9e-07
12324 49 4e-06
19094 49 6e-06
30755 48 1e-05
15910 48 1e-05
26560 46 3e-05
03240 46 3e-05
21210 45 4e-05
29687 45 6e-05
19761 45 8e-05
11185 44 1e-04
14257 42 5e-04
28638 42 5e-04
28095 42 7e-04
12786 41 9e-04
26711 41 0.001
05206 41 0.001
01494 41 0.001
37602 41 0.001
32000 40 0.002
18481 40 0.003
32264 39 0.004
35671 39 0.006
16716 38 0.010
17286 38 0.011
16708 38 0.012
30740 37 0.014
27405 37 0.017
38046 37 0.020
06462 36 0.033
21433 36 0.044
01392 35 0.049
07933 35 0.061
18881 35 0.062
13664 35 0.064
31789 34 0.13
02638 34 0.14
29360 34 0.16
37260 33 0.18
00394 32 0.55
18401 32 0.82
17516 31 0.87
13641 31 1.0
27287 31 1.2
23319 31 1.3
29590 30 1.9
36481 30 2.5
27562 29 3.3
18050 28 6.4
15741 28 7.0
18663 28 7.2
>21808
Length = 1011
Score = 318 bits (816), Expect(2) = 5e-88, Method: Compositional matrix adjust.
Identities = 152/225 (67%), Positives = 180/225 (80%), Gaps = 1/225 (0%)
Frame = +1
Query: 233 GTWNGNTKVAIKTLKPGTMSPESFLEEAQIMKKLKHDKLVQLYAVVSEE-PIYIVTEYMN 291
G WN T VAIKTLK GTM P+ FL EAQIMKKL+H KL+QLYAV +++ PI+I+TE M
Sbjct: 4 GLWNNTTPVAIKTLKSGTMDPKDFLAEAQIMKKLRHPKLIQLYAVCTQDDPIFIITELMK 183
Query: 292 KGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKI 351
GSLL+FL+ G+GR LKLP L+D+ AQ+A GMAY+E NYIHRDL + NILV + KI
Sbjct: 184 NGSLLEFLQ-GKGRVLKLPALIDIGAQIACGMAYLESQNYIHRDLAARNILVSDNNTVKI 360
Query: 352 ADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVP 411
ADFGLAR+I+++EY AR GA+FPIKWTAPEAA Y RFTIKSDVWSFGILLTE VT GRVP
Sbjct: 361 ADFGLARVIKEDEYEARVGARFPIKWTAPEAANYNRFTIKSDVWSFGILLTETVTYGRVP 540
Query: 412 YPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKKDPEERP 456
YPGM N EVL QVE GYRMPCP CP L+++M+ CW+K+ ERP
Sbjct: 541 YPGMTNAEVLHQVEHGYRMPCPPGCPKPLYDIMLECWRKEEMERP 675
Score = 25.0 bits (53), Expect(2) = 5e-88, Method: Compositional matrix adjust.
Identities = 11/22 (50%), Positives = 14/22 (63%)
Frame = +2
Query: 456 PTFEYLQSFLEDYFTATEPQYQ 477
PTFE LQ LE++FT Y+
Sbjct: 674 PTFETLQWKLEEFFTMDSKDYR 739
>06405
Length = 1965
Score = 249 bits (637), Expect = 1e-66, Method: Compositional matrix adjust.
Identities = 143/350 (40%), Positives = 197/350 (56%), Gaps = 57/350 (16%)
Frame = +1
Query: 177 ESETTKGAYSLSIRDWDDMKGDHVKHYKIRKLDNGGYYITTRAQFETLQQLVQHYSGTWN 236
ESE++ G S+S+R +G V HY+I + D+G ++T +F TL +LV H+S +
Sbjct: 1 ESESSPGQRSISVR----FEG-RVYHYRITE-DDGKVFVTQEHRFNTLAELVHHHSIHAD 162
Query: 237 G------------------------------NTKVAI----------------------- 243
G T++A+
Sbjct: 163 GLVTTLLYPAPKRQKPTVFGVSPEPDRWEIERTEIAMKHRLGGGQYGDVYEAMWKRYNKI 342
Query: 244 ---KTLKPGTMSPESFLEEAQIMKKLKHDKLVQLYAVVSEE-PIYIVTEYMNKGSLLDFL 299
KTLK TM+ FLEEA IMK++KH LVQL V + E P YIVTE+M G+LLD+L
Sbjct: 343 VAVKTLKEDTMALNDFLEEAAIMKEMKHPNLVQLLGVCTREPPFYIVTEFMPHGNLLDYL 522
Query: 300 KDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARL 359
+ L+ MA Q+A+GMAY+E N+IHRDL + N LV + + K+ADFGLARL
Sbjct: 523 RSSTREENGPTALMYMATQIASGMAYLETKNFIHRDLAARNCLVADSNMVKVADFGLARL 702
Query: 360 IEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNRE 419
++D+ YTA GAKFPIKWTAPE + RF+ +SD+W+FG+LL EL T G PYPG+ E
Sbjct: 703 MKDDTYTAHIGAKFPIKWTAPEGLAFNRFSTRSDIWAFGVLLWELATYGMSPYPGVELTE 882
Query: 420 VLEQVERGYRMPCPQDCPISLHELMIHCWKKDPEERPTFEYLQSFLEDYF 469
V +ERGYRM P P ++ LM+ CW+ DP++RPTF+ + LE+ F
Sbjct: 883 VYHLLERGYRMERPPGTPADVYILMLKCWQWDPKDRPTFKEIHFLLENMF 1032
>11780
Length = 1713
Score = 147 bits (371), Expect(2) = 3e-55, Method: Compositional matrix adjust.
Identities = 106/340 (31%), Positives = 160/340 (47%), Gaps = 60/340 (17%)
Frame = +3
Query: 103 FHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYVAP--VDSIQAEEWYFGKLGRKDAE 160
F KG+ I ++ W + G G IP+NYV P V ++ A W+ GK+ R+ AE
Sbjct: 111 FQKGDLLVIRRATSDRMWYKACDSNGREGMIPANYVQPRKVVTLHAMPWFHGKITRQQAE 290
Query: 161 RQLLSFGNPR--GTFLIRESETTKGAYSLSI--------------------------RDW 192
L PR G FLIRES G Y+L + R+
Sbjct: 291 ELL----KPREDGLFLIRESSNYPGDYTLCVCHLGKVEHYRILYRENQLTIDEEGFFRNL 458
Query: 193 DDMKGDHVKHY-------------------------KIRKLDNGGYYITTRAQFETLQQL 227
D++ VKHY +++ +GG+ I + E + +
Sbjct: 459 DEL----VKHYLADADGLCTQLTRPVTKQGGNFGTVSLQEFKSGGWVIAXQ-DLEIGEAI 623
Query: 228 VQH-----YSGTWNGNTKVAIKTLKPGTMSPESFLEEAQIMKKLKHDKLVQLYAVVSEEP 282
+ Y G + G VAIK LK +SFL+EA +M L+HD LV+L VV E
Sbjct: 624 GKGDFGDVYKGMYRGQP-VAIKQLKDKDRGEQSFLQEASVMTSLRHDNLVRLIGVVLGET 800
Query: 283 IYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANIL 342
I++VTE+M KG+L+++L+ + + ++ A A M Y+E +HRDL + N+L
Sbjct: 801 IFLVTEFMGKGNLVEYLRSRGRSVITKKDQINFATDTCAAMEYLESKRLVHRDLAARNVL 980
Query: 343 VGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEA 382
V + K++DFGLA+ + ++ + KFPIKWTAPEA
Sbjct: 981 VHDDGKAKVSDFGLAKFGDFSQTS----VKFPIKWTAPEA 1088
Score = 86.7 bits (213), Expect(2) = 3e-55, Method: Compositional matrix adjust.
Identities = 41/86 (47%), Positives = 57/86 (66%)
Frame = +1
Query: 387 RFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIH 446
+FT KSD+WSFGILL E+ + GRVPYP + +V+ VERGYRM P+ CP ++ +M
Sbjct: 1102 KFTSKSDMWSFGILLWEIYSFGRVPYPRIPLTDVVMHVERGYRMEAPEGCPPEIYSIMKQ 1281
Query: 447 CWKKDPEERPTFEYLQSFLEDYFTAT 472
W+ DP ERPTF+ + + L + T
Sbjct: 1282 AWELDPNERPTFKSVLARLNNQRAVT 1359
>04852
Length = 1462
Score = 148 bits (373), Expect = 6e-36, Method: Compositional matrix adjust.
Identities = 87/259 (33%), Positives = 136/259 (52%), Gaps = 31/259 (11%)
Frame = +1
Query: 239 TKVAIKTLKPGTMSPE--SFLEEAQIMKKLK----HDKLVQLYAVVSEE-PIYIVTEYMN 291
+ VA+K L+ + E F++E Q+MK +K H +V ++ P++++ E+
Sbjct: 22 STVAVKMLRDIVTAVEEQDFVQELQVMKAVKKMGSHINIVNFLGCCTQGGPLWVIVEFAK 201
Query: 292 KGSLLDFL---KDG--------------------EGRALKLPNLVDMAAQVAAGMAYIER 328
G+L DFL +DG G ++ NL+ A Q+A GM ++
Sbjct: 202 NGNLRDFLESCRDGINGYGKFVSPQDPGWYTKTPGGHVIRRKNLLSYAFQIARGMEFLAS 381
Query: 329 MNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRF 388
IHRDL + N+LV + KIADFGL+R + Y R G + P+KW APEA R+
Sbjct: 382 RKCIHRDLAARNVLVTEEHVLKIADFGLSR--TGDYYKKRSGGRLPVKWMAPEALFDMRY 555
Query: 389 TIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQ-VERGYRMPCPQDCPISLHELMIHC 447
T KSDVWSFG++L E+ + G +PY + N E+ + ++ YRMP P+ +L+ +M C
Sbjct: 556 TTKSDVWSFGVVLWEIFSLGGMPYASIPNEELYSKLLDDAYRMPRPELASGNLYAIMERC 735
Query: 448 WKKDPEERPTFEYLQSFLE 466
W P +RP F L ++
Sbjct: 736 WLNRPSDRPEFSQLVGHID 792
>09007
Length = 1440
Score = 142 bits (359), Expect = 2e-34, Method: Compositional matrix adjust.
Identities = 91/272 (33%), Positives = 146/272 (53%), Gaps = 11/272 (4%)
Frame = -1
Query: 218 RAQFETLQQLVQHYSGTWNGNTKVAIKTLKPGTMSP--ESFLEEAQIMKKLKHDKLVQLY 275
+ F T++Q + ++ +VA+K L + + FL+E IM+ L H+ +V++Y
Sbjct: 849 QGHFGTVRQAI--WTAESGEKVQVAVKCLSKDKIHKDGQEFLKETAIMQMLDHENIVRVY 676
Query: 276 AVVSEE--PIYIVTEYMNKGSLLDFLKDGEGRA-LKLPNLVDMAAQVAAGMAYIERMNYI 332
VV + I +VTE SLL+ +K+ R +P L D + QV GM+Y+E +
Sbjct: 675 GVVMDNGADIMLVTELAPMRSLLECVKEVSARVDFSVPRLCDFSQQVCDGMSYLESKRLV 496
Query: 333 HRDLRSANILVGNGLICKIADFGLA-RLIEDNEYTARQGA---KFPIKWTAPEAALYGRF 388
HRDL + NIL+ + KI+D G++ L EY Q + + W APE+ F
Sbjct: 495 HRDLAARNILLFSKSKVKISDVGVSGALGAGKEYYQSQQTIHLQNAVAWCAPESFRNLCF 316
Query: 389 TIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVE--RGYRMPCPQDCPISLHELMIH 446
+ SDVW+FG+LL E T G P+ G+N ++++E V+ + R+ P CP + +M+
Sbjct: 315 SSASDVWAFGVLLWEFFTHGFQPWAGLNGQQIMEAVDAPQSQRLEQPDLCPKEYYAVMLK 136
Query: 447 CWKKDPEERPTFEYLQSFLEDYFTATEPQYQP 478
CW+++P+ RPTF L FL T PQ +P
Sbjct: 135 CWEQEPQRRPTFSQL--FL------TLPQIRP 64
>17300
Length = 480
Score = 123 bits (308), Expect(2) = 2e-33, Method: Compositional matrix adjust.
Identities = 56/117 (47%), Positives = 83/117 (70%), Gaps = 4/117 (3%)
Frame = +1
Query: 319 VAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDN----EYTARQGAKFP 374
+++GM + M Y+HRDL + NILV L+CK+ADFGL+R IE + YT + G K P
Sbjct: 1 ISSGMGXLADMGYVHRDLAARNILVNEILVCKVADFGLSREIESDTTEGAYTTK-GGKIP 177
Query: 375 IKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMP 431
++WTAPEA Y +FT SDVWSFG+++ E+++ G PY +N++V++ VE+GYR+P
Sbjct: 178 VRWTAPEAIAYRKFTSASDVWSFGVVMWEVMSYGERPYWNWSNQDVIKAVEKGYRLP 348
Score = 38.1 bits (87), Expect(2) = 2e-33, Method: Composition-based stats.
Identities = 16/43 (37%), Positives = 23/43 (53%), Gaps = 1/43 (2%)
Frame = +2
Query: 432 CPQ-DCPISLHELMIHCWKKDPEERPTFEYLQSFLEDYFTATE 473
CP DCP +LH+LM+ W+K+ RP + L+ A E
Sbjct: 344 CPSMDCPEALHQLMLDAWQKERSHRPKMSMVVKTLDKLIRAPE 472
>20640
Length = 1492
Score = 124 bits (312), Expect = 6e-29, Method: Compositional matrix adjust.
Identities = 59/144 (40%), Positives = 86/144 (59%), Gaps = 1/144 (0%)
Frame = +1
Query: 331 YIHRDLRSANILVGNGLICKIADFGLARLIED-NEYTARQGAKFPIKWTAPEAALYGRFT 389
Y+HRDL + N LVG+ L+ KI+DFGLAR + + Y + PI+W EA LY +F+
Sbjct: 7 YVHRDLATRNCLVGHDLVVKISDFGLARSVHSVDYYRGSEHDAIPIRWMPLEAILYNKFS 186
Query: 390 IKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWK 449
+SDVWSFG++L E+ PY G+ + EV+ V+ G + CP+ P ++ELM CW
Sbjct: 187 TQSDVWSFGVVLWEIFAFALQPYYGLTHEEVVRFVKEGKVLACPERTPPPMYELMKQCWH 366
Query: 450 KDPEERPTFEYLQSFLEDYFTATE 473
+ P RP+F L LE+ + E
Sbjct: 367 RRPATRPSFHTLHKTLENMHSKYE 438
>07291
Length = 833
Score = 122 bits (306), Expect = 3e-28, Method: Compositional matrix adjust.
Identities = 60/167 (35%), Positives = 98/167 (58%), Gaps = 2/167 (1%)
Frame = +1
Query: 304 GRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLA-RLIED 362
+ L + L+D Q+A GMAY++ + +HR+L + N +V +++D+G+ L
Sbjct: 31 SKMLTVVQLLDFGRQIADGMAYLQEVKVVHRNLAARNCIVTEDGRLQLSDYGVTGSLFPQ 210
Query: 363 NEYTARQG-AKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVL 421
+ YTA A+ +KW APE F+ KSDVW+FG++L EL+T+G PYP + N +L
Sbjct: 211 SYYTADDSPARDLVKWMAPETIDNFHFSSKSDVWAFGVVLWELLTRGITPYPDVENSSLL 390
Query: 422 EQVERGYRMPCPQDCPISLHELMIHCWKKDPEERPTFEYLQSFLEDY 468
++ G+RM P+ P ++E+M CW + PE+RP F L L+ +
Sbjct: 391 PYLKEGHRMKKPKQSPEPVYEMMTACWNESPEQRPDFAELNDQLKTF 531
>14116
Length = 1017
Score = 117 bits (294), Expect = 9e-27, Method: Compositional matrix adjust.
Identities = 65/185 (35%), Positives = 107/185 (57%), Gaps = 8/185 (4%)
Frame = -1
Query: 237 GNTKVAIKTL---KPGTMSPESFLEEAQIMKKLKHDKLVQLYAV---VSEEPIYIVTEYM 290
G+ VA+KTL P + +SFL+EA IMK H ++ L + + + P+ +V +M
Sbjct: 552 GDILVAVKTLHNNNPREIELQSFLQEALIMKDFHHSNVLTLIGICLNLDDMPL-VVLPFM 376
Query: 291 NKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICK 350
G LL +++D + + + +L+ +A GM Y+ + ++HRDL + N ++ K
Sbjct: 375 KHGDLLTYIRDDQHQP-TIKDLIMYGVDIARGMDYLAGLKFVHRDLAARNCMLDEDFHVK 199
Query: 351 IADFGLARLIEDNEYTARQG--AKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKG 408
+ADFGLAR I + EY + + AK P+KW A E+ G + K+DVWS+G++L EL+T+G
Sbjct: 198 VADFGLARDIYEKEYYSSENKKAKLPVKWMALESLEKGNYDSKTDVWSYGVVLWELLTRG 19
Query: 409 RVPYP 413
P
Sbjct: 18 SDALP 4
>08294
Length = 1849
Score = 104 bits (259), Expect = 8e-23, Method: Compositional matrix adjust.
Identities = 64/206 (31%), Positives = 100/206 (48%), Gaps = 11/206 (5%)
Frame = +2
Query: 271 LVQLYAVVSE-EPIYIVTEYMNKGSLLDFL-----KDGEGRALKLPNL-----VDMAAQV 319
+V V E EP +++TEY + G L FL +G GR ++P L + M QV
Sbjct: 893 IVHFMGVCREAEPHFLITEYCDWGDLKQFLLATRNDNGRGRGTRVPALALSQKLGMGQQV 1072
Query: 320 AAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTA 379
AAGM + +H DL + N+L+ + + K+A L+ + +EY P++W
Sbjct: 1073 AAGMEALSNQGLVHGDLAARNVLLTSRMQLKVARPALSGDVYASEYYPLHQRLVPLRWLP 1252
Query: 380 PEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPIS 439
PE L T DVW+FG+ L E++ +PY M++ EVL ++ D P +
Sbjct: 1253 PEGVLEDSATTCGDVWAFGVFLWEVLQLADLPYRLMSDEEVLRSLQHSQAALDSPDAPPA 1432
Query: 440 LHELMIHCWKKDPEERPTFEYLQSFL 465
L L+ C + P +RP F + S L
Sbjct: 1433 LLSLLQRCTAQQPSQRPPFSEICSVL 1510
>18996
Length = 491
Score = 98.6 bits (244), Expect = 6e-21, Method: Compositional matrix adjust.
Identities = 55/136 (40%), Positives = 79/136 (58%), Gaps = 6/136 (4%)
Frame = +2
Query: 332 IHRDLRSANILVGNGLICKIADFGLARLIE-DNEYTARQGAKFPIKWTAPEAALYGRFTI 390
IHRDL + NILV + KI+DFGLA+ D Y PIKW +PEA +F+
Sbjct: 2 IHRDLAARNILVDRSCV-KISDFGLAQFANADGYYYGISQRDIPIKWYSPEAIETCKFSS 178
Query: 391 KSDVWSFGILLTELVTKGRVP--YPG--MNNREVLEQVERGYRMPCPQDCPISLH-ELMI 445
SDVWS+G+ L E+ ++G +P PG + E L ++ +G R+P P+ C ++ ELM
Sbjct: 179 YSDVWSYGVTLFEMFSRGEIPNLLPGHDLTQEEFLNRLRKGERLPKPELCSDFVYSELMR 358
Query: 446 HCWKKDPEERPTFEYL 461
CW + P+ RPTF +
Sbjct: 359 PCWHEMPKSRPTFHQI 406
>07940
Length = 1336
Score = 97.4 bits (241), Expect = 1e-20, Method: Compositional matrix adjust.
Identities = 49/112 (43%), Positives = 68/112 (60%), Gaps = 1/112 (0%)
Frame = -3
Query: 305 RALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNE 364
+ L +L+ A QVA GM Y+ IHRDL + N+LV + KIADFGL R ++ +
Sbjct: 362 KMLTPKDLISYAYQVARGMEYLASKQCIHRDLAARNVLVAEEYVLKIADFGLTRNLQQFD 183
Query: 365 YTARQ-GAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGM 415
Y + + P+KW APEA ++T KSDVWS+G+LL E+ T G PYP +
Sbjct: 182 YYRKTTDGRLPVKWMAPEALFDRKYTSKSDVWSYGVLLWEIFTLGGNPYPSV 27
Score = 36.6 bits (83), Expect = 0.022, Method: Compositional matrix adjust.
Identities = 21/69 (30%), Positives = 36/69 (52%), Gaps = 4/69 (5%)
Frame = -3
Query: 236 NGNTKVAIKTLKPGTMSPE--SFLEEAQIMKKL-KHDKLVQLYAVVSEE-PIYIVTEYMN 291
N + VA+K LK E + E ++MK + KH ++ L ++ +Y++ E+
Sbjct: 758 NNSVTVAVKMLKEDATDREMMDLIREMEMMKVIGKHKNIINLLGCCTQRGALYVIVEFAP 579
Query: 292 KGSLLDFLK 300
G+L DFLK
Sbjct: 578 HGNLRDFLK 552
>22005
Length = 873
Score = 82.4 bits (202), Expect(2) = 3e-20, Method: Compositional matrix adjust.
Identities = 58/194 (29%), Positives = 91/194 (46%), Gaps = 44/194 (22%)
Frame = +1
Query: 256 FLEEAQIMKKLKHDKLVQLYAVVS-EEPIYIVTEYMNKGSLLDFLKDGEGRALKLP---- 310
F EA +M H +V+L V + +P+ ++ E+M+KG L DFL+ LP
Sbjct: 151 FEREASLMADFDHPNIVKLLGVCAIGKPMCLLFEFMSKGDLNDFLRLCSPENYNLPVSRS 330
Query: 311 -NLVD-------------------------------------MAAQVAAGMAYIERMNYI 332
NLV ++ Q++AGMAY+ + +Y+
Sbjct: 331 QNLVVDLEDGLRVEVEAEECEKDTQSEDRDCSGMLXTKDQLYISQQISAGMAYLAQKDYV 510
Query: 333 HRDLRSANILVGNGLICKIADFGLARLIEDNEY-TARQGAKFPIKWTAPEAALYGRFTIK 391
HRDL + + I+DFGLAR + +Y + PI+W EA LY +F+ +
Sbjct: 511 HRDL-ATRTVXSRTT*S*ISDFGLARSVHSVDYYRGSEQDAIPIRWMPLEAILYSKFSTQ 687
Query: 392 SDVWSFGILLTELV 405
SDVWSFG++L E++
Sbjct: 688 SDVWSFGVVLWEIL 729
Score = 34.3 bits (77), Expect(2) = 3e-20, Method: Compositional matrix adjust.
Identities = 15/42 (35%), Positives = 24/42 (57%)
Frame = +3
Query: 411 PYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKKDP 452
PY G+ + EV+ V+ G + P P ++ELM CW++ P
Sbjct: 744 PYYGLTHEEVVNYVKAGKILEQPTKTPHQVYELMKQCWQRRP 869
>17637
Length = 447
Score = 92.8 bits (229), Expect = 3e-19, Method: Compositional matrix adjust.
Identities = 46/132 (34%), Positives = 74/132 (56%), Gaps = 1/132 (0%)
Frame = +1
Query: 340 NILVGNGLICKIADFGLARLIEDNEYTARQGAKF-PIKWTAPEAALYGRFTIKSDVWSFG 398
N ++ + L K+ D L+R + +Y ++ PIKW + EA + SDVWSFG
Sbjct: 1 NCVIDDQLRVKLTDSALSRDLFSGDYNCLGDGEYRPIKWLSLEALQKSHYNEGSDVWSFG 180
Query: 399 ILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKKDPEERPTF 458
+L+ E+ T G++PY ++ E+ ++ GYR+ P +CP L +M +CW P ERP+F
Sbjct: 181 VLMWEMCTLGKLPYAEIDPYEMEHYLKDGYRLAQPFNCPDELFTIMAYCWASMPAERPSF 360
Query: 459 EYLQSFLEDYFT 470
LQ L ++ T
Sbjct: 361 SQLQICLSEFHT 396
>01718
Length = 959
Score = 85.9 bits (211), Expect = 3e-17, Method: Compositional matrix adjust.
Identities = 77/245 (31%), Positives = 119/245 (48%), Gaps = 18/245 (7%)
Frame = +3
Query: 243 IKTLKPGTMSP--ESFLEEAQIMKKLKHDKLVQLYAV-VSEEPIYIVTEYMNKGSLLDFL 299
+ LK TM+ + L E Q++ +L+H +++ V V E ++ +TEY+ G+L L
Sbjct: 228 VMALKMNTMTSNRHNMLREVQLLNRLQHANILRFMGVCVHEGQLHALTEYIPSGNLEQLL 407
Query: 300 --KDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILV----GNGLICKIAD 353
KD E L + + +A G+ Y+ +IHRDL S NIL+ +G IAD
Sbjct: 408 EKKDEE---LPWTQRIQLTLGLARGLDYLHSTRFIHRDLTSKNILIRREDNHGYHAVIAD 578
Query: 354 FGLARLIE---DNEYTARQGAKFPIKWTAPEAALYGRF-TIKSDVWSFGILLTELVTKGR 409
FGLA I D E G+ + W APE L G F ++D++S GI++ E+ R
Sbjct: 579 FGLATKIPDPLDKEKLPTVGSPY---WMAPE-VLNGHFYNERADLFSVGIIMCEIT--AR 740
Query: 410 VP-----YPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKKDPEERPTFEYLQSF 464
+P P MNN V + V + CP+ +L C + DP++RP + +
Sbjct: 741 IPADPDIMPRMNNFGV-DYVALSEMI---SYCPLDYLQLAFKCCQVDPQKRPRGVEIIEW 908
Query: 465 LEDYF 469
LE F
Sbjct: 909 LEKIF 923
>13592
Length = 980
Score = 82.4 bits (202), Expect = 4e-16, Method: Compositional matrix adjust.
Identities = 65/252 (25%), Positives = 126/252 (50%), Gaps = 14/252 (5%)
Frame = +2
Query: 218 RAQFETLQQLVQHYSGTWNGNTKVAIKTLKPG-TMSPESFLEEAQIMKKLKHDKLVQLYA 276
+ +F + V + +G ++AI+ PG T + ++ EE +I++ +KH LV+ Y
Sbjct: 14 QGRFGKVYTAVNNNTGELMAMKEIAIQ---PGETRALKNVAEELKILEGIKHKNLVRYYG 184
Query: 277 V-VSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVD--MAAQVAAGMAYIERMNYIH 333
+ V E + I E ++G+L ++ G LP + AQ+ +G+A + + +H
Sbjct: 185 IEVHREELLIFMELCSEGTLESLVELTGG----LPEALSRRFTAQLLSGVAELHKHGIVH 352
Query: 334 RDLRSANILVGNGL-ICKIADFGLARLIEDNE--------YTARQGAKFPIKWTAPEAAL 384
RD+++ANI + +G K+ DFG A I+ + Y Q P +T +
Sbjct: 353 RDIKTANIFLVDGSNSLKLGDFGSAVKIQAHTTVPGELQGYVGTQAYMAPEVFTKTNSDG 532
Query: 385 YGRFTIKSDVWSFGILLTELVTKGRVPYPGMN-NREVLEQVERGYRMPCPQDCPISLHEL 443
+GR +D+WS G ++ E+ + G+ P+ + N +++ +V G + P+ H+
Sbjct: 533 HGRL---ADIWSVGCVVVEMAS-GKRPWAQFDSNFQIMFKVGMGEKPQAPESLSQEGHDF 700
Query: 444 MIHCWKKDPEER 455
+ HC + DP++R
Sbjct: 701 IDHCLQHDPKQR 736
>14477
Length = 493
Score = 79.7 bits (195), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 47/135 (34%), Positives = 79/135 (58%), Gaps = 5/135 (3%)
Frame = -1
Query: 241 VAIKTLKPGTMSPE---SFLEEAQIMKKLKHDKLVQLYAVVSEEPIYIVTEYMNKGSLLD 297
VAIK LK + P ++EA++MKK+ H +V+L + E + +V E G L
Sbjct: 400 VAIKVLKNADLDPSVQSELIKEAEVMKKMDHMHIVRLIGLCEGETMMLVLELAKLGPLNK 221
Query: 298 FLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLA 357
FL + + L L N++++ QV+ GM Y+E ++HRDL + NIL+ + KI+DFG++
Sbjct: 220 FLP--KNKHLPLWNILELMWQVSQGMEYLEANKFVHRDLAARNILLCDEHFAKISDFGMS 47
Query: 358 RLI--EDNEYTARQG 370
+ + E+N Y A++
Sbjct: 46 KTLSRENNYYMAQEA 2
>13305
Length = 549
Score = 79.7 bits (195), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 35/102 (34%), Positives = 59/102 (57%), Gaps = 4/102 (3%)
Frame = +2
Query: 370 GAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYR 429
+ PI+W A E+ +T +SDVWSFG++L E+ T G PY + +++ ++ GYR
Sbjct: 2 STRVPIRWMAVESLFNNTYTTQSDVWSFGVVLWEIFTLGGTPYSSTDTQQLFAFLKDGYR 181
Query: 430 MPCPQDCPISLHELMIHCWKKDPEERPTFE----YLQSFLED 467
+ P+ C + + +M+ CW ++ + RPTF LQ L+D
Sbjct: 182 LKRPKLCDQNTYAMMLQCWNENAQRRPTFPELCGRLQRMLDD 307
>00715
Length = 1788
Score = 76.6 bits (187), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 62/223 (27%), Positives = 103/223 (46%), Gaps = 31/223 (13%)
Frame = +1
Query: 266 LKHDKLVQLYAVVS----EEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAA 321
L+H +V + S E+ ++ EY+ +L L D + + + + +A Q+A
Sbjct: 97 LRHVNVVSILGATSLHRFEDGAWLAMEYVGPLNLQTILNDHQ-QDIDSSMRLSLALQMAR 273
Query: 322 GMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLI----------------EDNEY 365
G+ Y+ +N +H DL+ AN L+ L +IADFG + + E
Sbjct: 274 GLHYLHSINIVHLDLKPANCLLTRDLKLRIADFGCCHQLTPTGLDMGEREGGMAGNELEL 453
Query: 366 TARQGA-----KFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREV 420
T QGA + + APE + +++SDV+S GI L ++ T+ + PY G+ V
Sbjct: 454 TPVQGAWKNELAGTLAYRAPELLKGLQPSVRSDVYSLGITLWQMCTR-QGPYEGVPAHAV 630
Query: 421 LEQVERGYRMPCP----QDCP--ISLHELMIHCWKKDPEERPT 457
+ QV PCP +D P + +L CW + E+RPT
Sbjct: 631 VYQVVSKDLRPCPPPSTEDDPFEVMFRDLYTQCWARRVEDRPT 759
>01756
Length = 1858
Score = 73.2 bits (178), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 61/229 (26%), Positives = 102/229 (44%), Gaps = 16/229 (6%)
Frame = -3
Query: 198 DHVKHYKIRKLDNGGYYITTRAQFETLQQLVQHYSGTWNGNTKVAIKTLKPGTMSPESFL 257
+ K+ K+ K+ G + +A+ + +Q+V KV + K G P + L
Sbjct: 1748 EDAKYEKLAKIGQGTFGEVFKARCKKTKQVV--------AMKKVLMDNEKEGF--PITAL 1599
Query: 258 EEAQIMKKLKHDKLVQLYAVVSEEP---------IYIVTEYMNKGSLLDFLKDGEGRALK 308
E +I++ L H+ +V L + S + Y+V E+ L L
Sbjct: 1598 REIKILQLLNHENVVDLIEICSTKATSANRYKSMFYLVFEFCEHD--LAGLLSNMSVVFN 1425
Query: 309 LPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLAR-----LIEDN 363
LP + ++ Q+ G+ YI R +HRD+++ANIL+ + K+ADFGLAR L + N
Sbjct: 1424 LPEIKEVMKQLMNGLYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPN 1245
Query: 364 EYTARQGAKFPIKWTAPEAALYG--RFTIKSDVWSFGILLTELVTKGRV 410
YT R W P L G ++ D W G ++ E+ T+ +
Sbjct: 1244 RYTNR----VVTLWYRPPELLLGDRNYSTAIDQWGAGCIMAEMWTRNPI 1110
>17253
Length = 483
Score = 72.4 bits (176), Expect = 4e-13, Method: Compositional matrix adjust.
Identities = 45/153 (29%), Positives = 69/153 (45%), Gaps = 16/153 (10%)
Frame = -1
Query: 241 VAIKTLKPGTMSPES--FLEEAQIMKKL-KHDKLVQLYAVVS-EEPIYIVTEYMNKGSLL 296
VA+KT E FL E IM+KL +H +V + +P I+ E+ G LL
Sbjct: 459 VAVKTHNEAATDAEKSEFLRELSIMRKLPRHPNVVSFMGCCTMSDPALILMEFCCHGDLL 280
Query: 297 DFLKD----------GEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNG 346
FL+ L + A VA GMA++ +HRD+ + N+L+
Sbjct: 279 SFLRKRRPDRTVFLTSTANDLTARDFFSFALHVARGMAHVANNKIVHRDVAARNVLISER 100
Query: 347 LICKIADFGLARLIEDNE--YTARQGAKFPIKW 377
+CK++DFGL+R + D Y P++W
Sbjct: 99 NVCKVSDFGLSRRVGDQNDVYEIVSRRPLPLRW 1
>19301
Length = 712
Score = 69.7 bits (169), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 35/94 (37%), Positives = 55/94 (58%), Gaps = 1/94 (1%)
Frame = +2
Query: 263 MKKLKHDKLVQLYAVVSEEPIY-IVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAA 321
++KL H ++ V ++ P Y I+ EY G L + L+DG+ L ++D + Q+A+
Sbjct: 431 LRKLNHPNIISFKGVCTQAPCYCIIMEYCPYGQLYEVLRDGKEIPPAL--VLDWSKQIAS 604
Query: 322 GMAYIERMNYIHRDLRSANILVGNGLICKIADFG 355
GM Y+ IHRDL+S N+LV + KI+DFG
Sbjct: 605 GMNYLHSHKIIHRDLKSPNVLVAKNDVVKISDFG 706
>01707
Length = 757
Score = 68.6 bits (166), Expect = 6e-12, Method: Compositional matrix adjust.
Identities = 65/234 (27%), Positives = 114/234 (48%), Gaps = 8/234 (3%)
Frame = +1
Query: 201 KHYKIRKLDNGGYYITTRAQFETLQQLVQHYSGTWNGNTKVAIKTLKPGTMSP---ESFL 257
K+ KI K+ G Y + + + + QLV AIK P + +
Sbjct: 67 KYEKIGKIGEGSYGVVFKCRNKETSQLV-------------AIKKFVESEDDPLIKKIAM 207
Query: 258 EEAQIMKKLKHDKLVQLYAVVSEEP-IYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMA 316
E +++K+LKH LV+L V + +++V +Y++ +LL+ L D R L P + +
Sbjct: 208 REIRMLKQLKHPNLVRLIEVFRRKKRLHLVFDYVDH-TLLNEL-DRYPRGLPEPMVKRII 381
Query: 317 AQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIE--DNEYTARQGAKFP 374
Q + + + N IHRD++ NIL+ K+ DFG AR++ +EYT ++
Sbjct: 382 YQTLLAVNFCHQYNTIHRDVKPENILITRQGQVKLCDFGFARILTGPGDEYTDYVATRW- 558
Query: 375 IKWTAPEAALYG--RFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVER 426
+ APE L G ++ DVW+ G + EL+T G+ +PG ++ + L + +
Sbjct: 559 --YRAPE-LLVGDTQYGPPVDVWAIGCVFAELLT-GQALWPGRSDVDQLHLIRK 708
>29581
Length = 1278
Score = 66.6 bits (161), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 59/191 (30%), Positives = 91/191 (47%), Gaps = 11/191 (5%)
Frame = -2
Query: 246 LKPGTMSPESFLEEAQIMKKLKHDKLVQLYAVV---SEEPIYIVTEYMNK--GSLLDFLK 300
L+ +SP + + L+H +VQL VV S + +++V EY + SLLD +
Sbjct: 1244 LERDMVSPSVVCVRSTFLLNLRHQNIVQLQEVVVGKSLDSLFLVMEYCEQDLASLLDNMP 1065
Query: 301 DGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLI 360
+ + + Q+ G+ Y+ IHRDL+ +N+L+ + KIADFGLAR
Sbjct: 1064 APFSES----QVKCIVLQLLKGLRYLHEAFIIHRDLKVSNLLMTDKGCVKIADFGLAR-- 903
Query: 361 EDNEYTARQGAKFP----IKWTAPEAALYGRFTIKS--DVWSFGILLTELVTKGRVPYPG 414
Y Q P + + APE L+G T + D+WS G +L EL+ P
Sbjct: 902 ---NYGKPQKPMTPKVVTLWYRAPE-LLFGSKTHSTAIDMWSAGCILGELLGHK----PL 747
Query: 415 MNNREVLEQVE 425
M R L+Q+E
Sbjct: 746 MPGRSDLQQIE 714
>12721
Length = 821
Score = 66.2 bits (160), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 44/183 (24%), Positives = 86/183 (46%), Gaps = 2/183 (1%)
Frame = +1
Query: 254 ESFLEEAQIMKKLKHDKLVQLYA--VVSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPN 311
E E +M+ H +V++Y +V++E +++V E+M G+L D + + +++
Sbjct: 211 ELLFNEVVVMRDYHHPNIVEMYNSYLVNDE-LWVVMEFMEGGALTDIVTNNRMDEVQIAT 387
Query: 312 LVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGA 371
+ + +A++ IHRD++S +IL+ + K+ DFG + + +
Sbjct: 388 VCRACLK---ALAFLHANGVIHRDIKSDSILLSHDGKVKLXDFGFCAQVTQDLQKRKSLV 558
Query: 372 KFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMP 431
P W APE + + D+WS GI++ E++ P N L+ + R MP
Sbjct: 559 GTPY-WMAPEVISRLPYGPEVDIWSLGIMVMEMIDAE----PPFFNEPPLQAMRRIRDMP 723
Query: 432 CPQ 434
P+
Sbjct: 724 PPK 732
>01060
Length = 1800
Score = 66.2 bits (160), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 52/205 (25%), Positives = 97/205 (47%), Gaps = 7/205 (3%)
Frame = +1
Query: 253 PESFLEEAQIMKKLKHDKLVQLYAVVSE-EPIYIVTEYMNKGSLLDFLKDGEGRALKLPN 311
P S + E ++++L+H +V L V+ E E +++V E+++ + K EG L
Sbjct: 202 PSSAIREIAMLRELRHTNIVCLEDVIMEDERLFLVFEFLSMDLKMYIDKFPEGVVLDRRL 381
Query: 312 LVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGA 371
+ Q+ G+ + + +HRDL+ N+L+ + KIADFG+AR A
Sbjct: 382 VKSYVFQIVTGIXFCHQRRIVHRDLKPQNLLINHTGAIKIADFGMARTFA-LPVRAYTHE 558
Query: 372 KFPIKWTAPEAAL-YGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRM 430
+ + APE + +++ DVWS G + +++ + + + G + + L ++ R
Sbjct: 559 VVTLWYRAPEILMGASKYSTPVDVWSIGTIFADMLIRTPI-FKGDSEIDQLFKIFRIIGT 735
Query: 431 PCPQDCPISLHEL-----MIHCWKK 450
P Q P H+L M WK+
Sbjct: 736 PTEQTWP-EFHKLPAFNGMFPLWKE 807
>18484
Length = 635
Score = 63.2 bits (152), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 37/122 (30%), Positives = 65/122 (53%)
Frame = +1
Query: 303 EGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIED 362
EG+ K P AA++A G+ ++ I+RDL+ N+++ + KIADFG+ +
Sbjct: 25 EGK-FKEPVAAFYAAEIAVGLFFLHDQGIIYRDLKLDNVMLDSEGHIKIADFGMCKEGMT 201
Query: 363 NEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLE 422
+ T R P + APE LY ++ D W++G+LL E++ G+ P+ G + E+
Sbjct: 202 GDATTRTFCGTP-DYIAPEIVLYQPYSKSVDWWAYGVLLFEMLA-GQPPFDGEDEDELFS 375
Query: 423 QV 424
+
Sbjct: 376 SI 381
>25550
Length = 941
Score = 63.2 bits (152), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 29/60 (48%), Positives = 40/60 (66%)
Frame = +3
Query: 410 VPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKKDPEERPTFEYLQSFLEDYF 469
V YPG++ EV +ERGYRM PQ P ++ LM+ CW+ DP+ERPTF+ + LE+ F
Sbjct: 36 VXYPGVDLTEVYHLLERGYRMERPQGTPADVYILMLKCWQWDPKERPTFKEIHYLLENMF 215
>18921
Length = 697
Score = 63.2 bits (152), Expect = 3e-10, Method: Compositional matrix adjust.
Identities = 47/172 (27%), Positives = 80/172 (46%), Gaps = 1/172 (0%)
Frame = +2
Query: 241 VAIKTLKPGTMSPESFLEEAQIMKKLKHDKLVQLY-AVVSEEPIYIVTEYMNKGSLLDFL 299
+AIK + P + ++E IM++ +V+ Y + ++IV EY GS+ D +
Sbjct: 113 LAIKQV-PVDTDLQEIIKEISIMQQCDSKYIVKYYGSYFKNTDLWIVMEYCGAGSVSDIM 289
Query: 300 KDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARL 359
+ + L + + G+ Y+ IHRD+++ NIL+ N K+ADFG+A
Sbjct: 290 RL-RNKTLVEREIATILYYTLKGLXYLHSRRKIHRDIKAGNILLNNEGHAKLADFGVAGQ 466
Query: 360 IEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVP 411
+ D P W APE + +D+WS GI E+ +G+ P
Sbjct: 467 LTDTMAKRNTVIGTPY-WMAPEVIQEIGYDCVADIWSLGITALEM-AEGKPP 616
>14420
Length = 528
Score = 62.0 bits (149), Expect = 5e-10, Method: Compositional matrix adjust.
Identities = 39/162 (24%), Positives = 79/162 (48%), Gaps = 3/162 (1%)
Frame = +2
Query: 254 ESFLEEAQIMKKLKHDKLVQ-LYAVVSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNL 312
E + E +M++ ++ +V L + + E +++V E++ GSL D + + + +
Sbjct: 35 ELIINEILVMRENQNPNIVNYLDSYLVGEELWVVMEFLAGGSLTDVVTE---TCMDEGQI 205
Query: 313 VDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLI--EDNEYTARQG 370
+ + + ++ IHRD++S NIL+G K+ DFG + E ++ + G
Sbjct: 206 AAVCRECLQALEFLHENQVIHRDIKSDNILLGMDGSVKLTDFGFCAQLSPEQSKRSTMVG 385
Query: 371 AKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPY 412
+ W APE ++ D+WS G++ E++ +G PY
Sbjct: 386 TPY---WMAPEVVTRKQYGPTVDIWSLGVMCIEMI-EGEPPY 499
>04591
Length = 1117
Score = 61.2 bits (147), Expect = 9e-10, Method: Compositional matrix adjust.
Identities = 44/169 (26%), Positives = 83/169 (49%), Gaps = 14/169 (8%)
Frame = -2
Query: 253 PESFLEEAQIMKKLKHDKLVQLYAVVSEEP---------IYIVTEYMN--KGSLLDFLKD 301
P + L E +I+++L+H+ +VQL + + Y++ EY + LL+ L+
Sbjct: 1089 PITALREIKILQQLEHENVVQLQEICHTQAGPYNRYKSTFYLIFEYCDYDLAGLLNNLR- 913
Query: 302 GEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLAR-LI 360
L + ++ +Q+ G+ YI +HRD+++ANIL+ + K+ADFGL+R +
Sbjct: 912 ---VKFSLADKKNLMSQLLNGLFYIHTKQILHRDIKAANILLTRDGVLKLADFGLSRPWV 742
Query: 361 EDNEYTARQGAKFPIKWTAPEAALYG--RFTIKSDVWSFGILLTELVTK 407
+ T R W P L G + + D+W G ++ E+ ++
Sbjct: 741 KSKRLTNR----VVTLWYRPPELLLGEREYGPEIDMWGVGCIMAEMWSR 607
>27546
Length = 426
Score = 61.2 bits (147), Expect = 1e-09, Method: Composition-based stats.
Identities = 36/114 (31%), Positives = 56/114 (49%), Gaps = 7/114 (6%)
Frame = -1
Query: 256 FLEEAQIMKKLKHDKLVQLYAVVSEEP-IYIVTEYMNKGSLLDFLKDGEGRALKLPNLVD 314
F E +I+ +L H ++Q+++++ P I+I Y KG +L +K +D
Sbjct: 339 FPRELEILTRLDHPNIIQIHSILQRGPKIFIFMRYAEKGDMLSHIKK--------TGPID 184
Query: 315 MAA------QVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIED 362
A Q+A + Y+ + HRDL+ NIL+ L KIADFG AR D
Sbjct: 183 EAQTKVWFFQMAKALQYLHSHDIAHRDLKCENILLSKRLNVKIADFGFARYCRD 22
>14126
Length = 1265
Score = 60.1 bits (144), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 50/200 (25%), Positives = 93/200 (46%), Gaps = 11/200 (5%)
Frame = +3
Query: 253 PESFLEEAQIMKKLK---HDKLVQLYAVV------SEEPIYIVTEYMNKGSLLDFLKDGE 303
P + E ++K+L+ H +V+L V E + +V EY+ + L +L
Sbjct: 321 PMMAIREISMLKQLEQYEHPNVVRLLDVSHNTITDREIRLNLVFEYI-EHDLATYLAKCP 497
Query: 304 GRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDN 363
L + D+ Q+ G+ ++ +HRDL+ N+L+ K+ADFGLAR+ +
Sbjct: 498 SPGLGPDRIKDLMLQLLNGVDFLHSNRIVHRDLKPQNLLISKDGRLKLADFGLARIY--S 671
Query: 364 EYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQ 423
+ A + + +PE + + D+WS G + EL T+ R + G + + L++
Sbjct: 672 FHMALTTVVVTLWYRSPEVLMQAEYGTSVDIWSCGCIFAELFTR-RALFKGSSEFDQLKK 848
Query: 424 VERGYRMPCPQDCP--ISLH 441
+ +P D P +S+H
Sbjct: 849 IFEVIGLPPAGDWPEGVSVH 908
>00300
Length = 2318
Score = 59.3 bits (142), Expect = 4e-09, Method: Compositional matrix adjust.
Identities = 52/227 (22%), Positives = 105/227 (46%), Gaps = 12/227 (5%)
Frame = -1
Query: 256 FLEEAQIMKKLKHDKLVQLYAV-VSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPN--L 312
+E +I + ++H+ LV+ Y V V ++ + + EY + G++ + K G LP +
Sbjct: 1520 MCDEIKIFEGIQHENLVKYYGVEVHKDEMLMFMEYCDTGTIEEAAKMG------LPEYLI 1359
Query: 313 VDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDN-----EYTA 367
++ + ++ + +HRD++ ANI + + K+ DFG + ++ + E+
Sbjct: 1358 RRYTREIVLAVNHLHENSIVHRDIKGANIFLTSNGHVKLGDFGCSVKLKSHTTMPGEFHN 1179
Query: 368 RQGAK---FPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGM-NNREVLEQ 423
G P +T + YGR +D+WS G ++ E+ T G+ P+ + NN +++ +
Sbjct: 1178 LVGTTAYMAPEVFTQNDQGGYGR---AADIWSLGCVVIEMAT-GKRPWHDLDNNYQIMYK 1011
Query: 424 VERGYRMPCPQDCPISLHELMIHCWKKDPEERPTFEYLQSFLEDYFT 470
V G++ P + + DP +R L L+ FT
Sbjct: 1010 VGIGHKPAVPDSLSVEGKHFLDLIMCHDPAQRALASQL---LDHTFT 879
>11228
Length = 2155
Score = 58.5 bits (140), Expect = 6e-09, Method: Compositional matrix adjust.
Identities = 41/149 (27%), Positives = 75/149 (50%), Gaps = 5/149 (3%)
Frame = -2
Query: 88 VALYDYEARTE-DDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYVAPVDS--- 143
VA+ Y T+ D+LSF KG+ F + N E W T E+G +P+ +V +D
Sbjct: 1662 VAMLSYRKATDSDELSFCKGDVFVVQNEMEDGWLWVTCERTKESGLVPAPFVKDLDGDYE 1483
Query: 144 -IQAEEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDWDDMKGDHVKH 202
+++ ++ L +++A +L+ G G+FL+R+SE G YSL D V+
Sbjct: 1482 PVESLPYFHSCLSKEEAVEKLMLAGE--GSFLVRQSENYPGDYSLFFLCEKD-----VRR 1324
Query: 203 YKIRKLDNGGYYITTRAQFETLQQLVQHY 231
++I + G ++ F++L +++ Y
Sbjct: 1323 FRIER--RGNQFLVGGRLFDSLDGVIKRY 1243
Score = 37.0 bits (84), Expect = 0.016, Method: Compositional matrix adjust.
Identities = 22/57 (38%), Positives = 31/57 (54%)
Frame = -1
Query: 132 YIPSNYVAPVDSIQAEEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLS 188
+I S AP + WY G+LGR AE L G++L+RESE+ G++ LS
Sbjct: 2011 HINSALTAPDQKL----WYHGRLGRAGAEELLRD--QDAGSYLVRESESKLGSFVLS 1859
>00392
Length = 668
Score = 58.5 bits (140), Expect = 6e-09, Method: Compositional matrix adjust.
Identities = 53/174 (30%), Positives = 88/174 (50%), Gaps = 10/174 (5%)
Frame = +3
Query: 254 ESFLEEAQIMKKLKHDKLVQLYAVVSE------EPIYIVTEYMNKGSLLDFLKDGEGRAL 307
+ F EEA+++K+L+H +V+ + E + I +VTE M G+L +LK + +
Sbjct: 66 QRFKEEAEMLKELQHPNIVRFFDYWEEHNHRNRKVIILVTELMTSGTLKTYLKRFKKPNV 245
Query: 308 KLPNLVDMAAQVAAGMAYIERMN--YIHRDLRSANILV-GNGLICKIADFGLARLIEDNE 364
K+ L + QV G+ ++ IHRDL+ NI + G KI D GLA L N+
Sbjct: 246 KI--LKNWCRQVLKGLYFLHTRTPPVIHRDLKCDNIFITGPTGSVKIGDLGLATL--KNQ 413
Query: 365 YTARQGAKFPIKWTAPEAALY-GRFTIKSDVWSFGILLTELVTKGRVPYPGMNN 417
A+ P ++ APE +Y + DV++FG+ + E+ + PY +N
Sbjct: 414 SFAKSVIGTP-EFMAPE--MYEEHYDEAVDVYAFGMCMLEMAS-SEYPYSECSN 563
>01966
Length = 1735
Score = 58.2 bits (139), Expect = 7e-09, Method: Compositional matrix adjust.
Identities = 32/107 (29%), Positives = 58/107 (54%), Gaps = 1/107 (0%)
Frame = -1
Query: 253 PESFLEEAQIMKKLKHDKLVQLYAVVSE-EPIYIVTEYMNKGSLLDFLKDGEGRALKLPN 311
P S + E ++++L+H +V L V+ E E +++V E+++ + K EG L
Sbjct: 1582 PSSAIREIAMLRELRHTNIVCLEDVIMEDERLFLVFEFLSMDLKMYIDKFPEGVVLDRRL 1403
Query: 312 LVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLAR 358
+ Q+ G+ + + +HRDL+ N+L+ + KIADFG+AR
Sbjct: 1402 VKSYVFQIVTGINFCHQRRIVHRDLKPQNLLINHTGAIKIADFGMAR 1262
>07836
Length = 1478
Score = 57.0 bits (136), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 62/217 (28%), Positives = 100/217 (46%), Gaps = 42/217 (19%)
Frame = -1
Query: 283 IYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIE--------RMNYIHR 334
++++T+Y GSL D+L R L ++ +A G+A++ + HR
Sbjct: 1328 LFLITDYHENGSLHDYLL---SRVLDSSEMLALAHSAICGLAHLHIEIFGTRGKPAIAHR 1158
Query: 335 DLRSANILVGNGLICKIADFGLA-RLI-EDNEYTA----RQGAKFPIKWTAPEAALYGRF 388
D++S NILV C IAD GLA R I E NE RQG K ++ APE L
Sbjct: 1157 DIKSKNILVKKNGTCCIADLGLAVRYISESNEVDVAPNPRQGTK---RYMAPE-VLEMLL 990
Query: 389 TIK-------SDVWSFGILLTEL----VTKG-----RVPY-------PGMNNREVLEQVE 425
+K +D+++FG+++ E+ V G +VP+ P + ++ V+
Sbjct: 989 NVKNFDAFKQADMYAFGLVMWEIARCCVIGGVAEEYQVPFYNCLPHDPSFEDVRLVVSVD 810
Query: 426 RGYRMPCP---QDCPI--SLHELMIHCWKKDPEERPT 457
+ R P Q+ PI + ++M CW +P R T
Sbjct: 809 K-VRPDIPLRWQEDPIMKVMVKVMCECWSGNPAARLT 702
>31885
Length = 529
Score = 57.0 bits (136), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 46/169 (27%), Positives = 78/169 (46%), Gaps = 6/169 (3%)
Frame = -2
Query: 260 AQIMKKLKHDKLVQL-YAVVSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQ 318
++ +L H LV L YA EE +++V + G L ++ + + + + Q
Sbjct: 519 VDMLTRLDHPFLVNLWYAFQDEEDLFMVVDLFLGGDLRYHMQ--QEVSFREDCVKFYLCQ 346
Query: 319 VAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWT 378
+A + Y+ +HRD++ NIL+ C + DF +A +ED+E P +
Sbjct: 345 LALVLDYLRSQKIVHRDIKPDNILLDEQGHCHVTDFNIATQLEDDELATSTSGTRP--YM 172
Query: 379 APE---AALYGR--FTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLE 422
APE A+ R + D WS G+ L EL+ K R P+ +N + E
Sbjct: 171 APEVYGVAINERRGYGFPVDWWSLGVSLFELLKKRR-PFSVHSNTSLHE 28
>13066
Length = 551
Score = 55.8 bits (133), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 46/178 (25%), Positives = 79/178 (44%), Gaps = 12/178 (6%)
Frame = +3
Query: 233 GTWNG----NTKVAIKTL----KPGTMSPESFLEEAQIMKKLKHDKLVQLYAVVSEEPI- 283
GT+N N K+A K + P + F E ++ KL H ++Q+++++ P
Sbjct: 24 GTFNDGYGRNIKLACKIIDKEKAPVDFVEKFFPRELDLLTKLDHPYIIQIHSILQRXPKN 203
Query: 284 YIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILV 343
+I + +G LL +++ E +K Q+ + Y+ + HRDL+ NIL+
Sbjct: 204 FIFMRFAERGDLLTYIQ--EVGFVKEKQAKIWFYQMTTALNYLHSYDVAHRDLKCENILL 377
Query: 344 GNGLICKIADFGL--ARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIK-SDVWSFG 398
+ K+ADFG A + E E + + APE + K +D WS G
Sbjct: 378 SSHFNVKLADFGFACACITESGEKYMSRTYCGSAAYAAPEIVYGAPYAPKVADAWSLG 551
>12672
Length = 773
Score = 53.5 bits (127), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 40/164 (24%), Positives = 74/164 (45%), Gaps = 16/164 (9%)
Frame = +3
Query: 320 AAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPI---K 376
A+G+ Y+ ++HRD+++ANIL+ + K+ DF E Q A I
Sbjct: 21 ASGIQYLNDNGHVHRDIKTANILLDSEYTAKVGDFATVVSAPSGEGKTVQNASVVIGTAA 200
Query: 377 WTAPEAALYGRFTIKSDVWSFGILLTELVT----------KGRVPYPGMNNREVLEQVER 426
+ APE A++ + K D +SFG++L E++T + + M N E E++
Sbjct: 201 YLAPE-AIHFDVSTKLDSYSFGVVLLEVITGLVAQDYSREERTLSSHIMENVEEPEEIHD 377
Query: 427 GYRMPC---PQDCPISLHELMIHCWKKDPEERPTFEYLQSFLED 467
P L+++ + C ++RP + ++ LE+
Sbjct: 378 FVDQSAGTWPDGAVDKLYDISMRCLNLSKKQRPNVKDIRPELEE 509
>13212
Length = 1067
Score = 52.8 bits (125), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 45/167 (26%), Positives = 76/167 (45%), Gaps = 11/167 (6%)
Frame = -1
Query: 318 QVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKF---P 374
++ + ++ R + IHRD+++ N+L+ K+ADFG++ N T ++ F P
Sbjct: 956 EMCMALDFLHRHHVIHRDIKAGNVLLTIDGEVKLADFGVSA---KNTQTQQKRDTFIGTP 786
Query: 375 IKWTAPEAALY-----GRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERG-- 427
W APE L + K+D+WS G+ L E + P M+ VL ++ +
Sbjct: 785 Y-WMAPEVVLCETLKDTPYDFKADIWSLGVTLIEFA-QIEPPNKEMHPMRVLIKIHKSDP 612
Query: 428 YRMPCPQDCPISLHELMIHCWKKDPEERPT-FEYLQSFLEDYFTATE 473
+ P+ + + C KDP RPT E L+ TAT+
Sbjct: 611 PTLEKPKKWTKLFKDFIAKCLVKDPNLRPTAAELLEHPFMKRATATD 471
>09606
Length = 1300
Score = 52.4 bits (124), Expect = 4e-07, Method: Compositional matrix adjust.
Identities = 41/177 (23%), Positives = 76/177 (42%), Gaps = 22/177 (12%)
Frame = -3
Query: 260 AQIMKKLKHDKLVQLYA-VVSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQ 318
++ + H +VQ + + +++V E GSL D L + L ++ D
Sbjct: 980 VRMTHDISHPNVVQFHEWYETSNHLWLVVELCTGGSLADIL--AQDHHLPETSIRDFGIH 807
Query: 319 VAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYT-----ARQGAKF 373
+ G+ YI + + DLR + +L+ + K ADFGL+++ +N A G ++
Sbjct: 806 LVTGLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQW 627
Query: 374 PIK----------------WTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPG 414
I+ + APE +I SD+W+ G + E+ + G P+ G
Sbjct: 626 NIQSAEEMMKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFS-GHPPFLG 459
>04138
Length = 800
Score = 52.4 bits (124), Expect = 4e-07, Method: Compositional matrix adjust.
Identities = 32/93 (34%), Positives = 47/93 (50%), Gaps = 7/93 (7%)
Frame = +1
Query: 325 YIERMNYIHRDLRSANILVGNGLICKIADFGLAR-----LIEDNEYTARQGAKFPIKWTA 379
YI R +HRD+++ANIL+ + K+ADFGLAR L + N YT R W
Sbjct: 58 YIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNR----VVTLWYR 225
Query: 380 PEAALYG--RFTIKSDVWSFGILLTELVTKGRV 410
P L G ++ D W G ++ E+ T+ +
Sbjct: 226 PPELLLGDRNYSTAIDQWGAGCIMAEMWTRNPI 324
>21079
Length = 878
Score = 51.2 bits (121), Expect = 8e-07, Method: Compositional matrix adjust.
Identities = 39/143 (27%), Positives = 69/143 (48%), Gaps = 4/143 (2%)
Frame = +1
Query: 268 HDKLVQLY-AVVSEEPIYIVTEYMNKGSLLD-FLKDGEGRALKLPNLVDMAAQVAAGMAY 325
H KL+ L+ A + + +V E++ G L + ++D L + V Q+ +G+ Y
Sbjct: 1 HPKLLMLWDAFEAPRTMVLVMEFVGAGELFERVIRDD--FVLTERDCVHFVRQICSGVGY 174
Query: 326 IERMNYIHRDLRSANILV--GNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAA 383
+ + +H DL+ N+L N KI DFGLAR + + + Q ++ APE
Sbjct: 175 MHTQSILHLDLKPENVLCVSDNSNQIKIIDFGLARFYKPGD--SLQVLFGTPEFIAPEVV 348
Query: 384 LYGRFTIKSDVWSFGILLTELVT 406
Y +D+WS G++ L++
Sbjct: 349 NYDEINFTTDMWSIGVICYILLS 417
>29243
Length = 1147
Score = 51.2 bits (121), Expect = 9e-07, Method: Compositional matrix adjust.
Identities = 32/98 (32%), Positives = 51/98 (52%), Gaps = 2/98 (2%)
Frame = +2
Query: 136 NYVAPVDSIQAEEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETT--KGAYSLSIRDWD 193
+YV S+++ WY G + R A++ L + P GTFLIR + +G SLSI+
Sbjct: 269 DYVNEPCSLESYNWYVGIMERPVAQKXLDTC--PDGTFLIRVTNNPLRRGELSLSIK--- 433
Query: 194 DMKGDHVKHYKIRKLDNGGYYITTRAQFETLQQLVQHY 231
+ V+H K+ + G +Y+ F+ +Q LV HY
Sbjct: 434 --YANAVRHIKVNRNPQGRFYLADGRYFDNIQSLVDHY 541
Score = 40.4 bits (93), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 20/53 (37%), Positives = 28/53 (52%), Gaps = 2/53 (3%)
Frame = +2
Query: 88 VALYDYEARTEDDLSFHKGEKFQIL--NSSEGDWWEARSLTTGETGYIPSNYV 138
VA+YDY A + LS ++ IL N + WW+ +L T + GY P YV
Sbjct: 641 VAVYDYAATSTSQLSMKLNDRIAILSKNGQDKGWWKGENLRTQKIGYFPLAYV 799
>12324
Length = 946
Score = 48.9 bits (115), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 22/53 (41%), Positives = 32/53 (60%)
Frame = +3
Query: 88 VALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYVAP 140
VA+YDYEA +D+L+F + ++ ++ WWE + G TG PSNYV P
Sbjct: 699 VAIYDYEAEKDDELTFSENSVIYVIRKNDDGWWEG--VMDGVTGLFPSNYVEP 851
>19094
Length = 898
Score = 48.5 bits (114), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 28/83 (33%), Positives = 41/83 (49%)
Frame = +1
Query: 322 GMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPE 381
G+ Y+ IHRD+++ NIL+ N K+ADFG+A + D P W APE
Sbjct: 94 GL*YLHSRRKIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTP-YWMAPE 270
Query: 382 AALYGRFTIKSDVWSFGILLTEL 404
+ +D+WS GI E+
Sbjct: 271 VIQEIGYDCVADIWSLGITALEM 339
>30755
Length = 1137
Score = 47.8 bits (112), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 37/142 (26%), Positives = 66/142 (46%), Gaps = 2/142 (1%)
Frame = +2
Query: 316 AAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEY--TARQGAKF 373
A++ + + Y+ I+RDL+ N+L+ K+ADFGL + ED Y T +
Sbjct: 50 GAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCK--EDITYGRTTKTFCGT 223
Query: 374 PIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCP 433
P ++ APE + D W G+++ E++ GR+P+ + +VL + + P
Sbjct: 224 P-EYLAPEVLDDNDYGRAVDWWGTGVVMYEMIC-GRLPFYN-RDHDVLFTLILVEDVKFP 394
Query: 434 QDCPISLHELMIHCWKKDPEER 455
++ L+ KDP R
Sbjct: 395 RNITDEAKSLLSGLLAKDPRNR 460
>15910
Length = 1361
Score = 47.8 bits (112), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 34/114 (29%), Positives = 57/114 (50%), Gaps = 3/114 (2%)
Frame = +2
Query: 317 AQVAAGMAYIERMNYIHRDLRSANIL---VGNGLICKIADFGLARLIEDNEYTARQGAKF 373
+ + G+ YI +HRDL+ N+L + + K+ADFGL+R+IE E
Sbjct: 485 SDILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLADFGLSRIIEP-EVQMSTVCGT 661
Query: 374 PIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERG 427
P + APE ++T D+WS G++ L+ G P+ N E+ ++ +G
Sbjct: 662 P-GYCAPEVLKGDKYTPSVDMWSVGVIAYILLC-GYEPFFAENEFEMYRKIIKG 817
>26560
Length = 398
Score = 46.2 bits (108), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 32/103 (31%), Positives = 52/103 (50%), Gaps = 1/103 (0%)
Frame = -1
Query: 316 AAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPI 375
AA+V G+ ++ ++RDL+ ANIL+ +I+D GLA A G
Sbjct: 338 AAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGLACDFSKKRPHASVGTH--- 168
Query: 376 KWTAPEAALYGR-FTIKSDVWSFGILLTELVTKGRVPYPGMNN 417
+ APE + G+ + +D +SFG +L +L+ KG P+ N
Sbjct: 167 GYMAPEVLMKGQSYDSSADWFSFGCMLYKLL-KGHSPFRQHNQ 42
>03240
Length = 1683
Score = 46.2 bits (108), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 37/138 (26%), Positives = 65/138 (47%), Gaps = 8/138 (5%)
Frame = -3
Query: 242 AIKTLKPGTMSPESFLE----EAQIMKKLKHDKLVQLYAVVSEEP-IYIVTEYMNKGSLL 296
A+KTL+ + + + E I+ + ++ +V+LY + +Y V +Y+ G L+
Sbjct: 1204 AMKTLRKSDVLKRNQVAHVKAERDILAEADNEWVVKLYYSFQDHNYLYFVMDYVPGGDLM 1025
Query: 297 DFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGL 356
L E L P A++ + + RM +IHRD++ NIL+ K+ DFGL
Sbjct: 1024 GLLIRME--ILDEPLARFYVAELVQAIESVHRMGFIHRDIKPDNILIDRNGHIKLTDFGL 851
Query: 357 A---RLIEDNEYTARQGA 371
R +++Y R G
Sbjct: 850 CTGFRWTHNSKYYQRDGT 797
>21210
Length = 518
Score = 45.4 bits (106), Expect = 4e-05, Method: Compositional matrix adjust.
Identities = 34/86 (39%), Positives = 47/86 (54%), Gaps = 4/86 (4%)
Frame = +3
Query: 380 PEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPG-MNNREVLEQVERGYRMPC-PQDCP 437
P A+ +G + ++SDVWS GI L EL T GR PY ++ + L+QV RG PC P D
Sbjct: 42 PRASSHG-YDVRSDVWSLGITLMELAT-GRFPYRKWVSIFDQLQQVVRGV-APCLPHDGA 212
Query: 438 IS--LHELMIHCWKKDPEERPTFEYL 461
S + C KD ++RP + L
Sbjct: 213 FSHDFVNFVNKCLTKDEKQRPKYNKL 290
>29687
Length = 434
Score = 45.1 bits (105), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 22/55 (40%), Positives = 32/55 (58%)
Frame = -2
Query: 89 ALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYVAPVDS 143
AL+DY A+ ED+LSF KG ++ +G WW T + + PSNYV +D+
Sbjct: 286 ALHDYNAKREDELSFCKGAIITNVSRQDGGWWRG-DYGTKKQHWFPSNYVEEIDT 125
>19761
Length = 473
Score = 44.7 bits (104), Expect = 8e-05, Method: Compositional matrix adjust.
Identities = 34/119 (28%), Positives = 54/119 (45%), Gaps = 3/119 (2%)
Frame = -3
Query: 318 QVAAGMAYIERMN--YIHRDLRSANILVGNGLICKIADFGLAR-LIEDNEYTARQGAKFP 374
Q A+ + Y+ +HRDL+ NI V ++ D GLAR L ++ Q
Sbjct: 399 QTASALNYMHTHTPVILHRDLKPQNIYVTEKGDVRLGDLGLARKLTGPADFATSQVGT-- 226
Query: 375 IKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCP 433
I + +PE + KSD+WS G + ++ G+ M +L QV G ++P P
Sbjct: 225 IMYLSPEILSQQPYNSKSDIWSLGCVFYDIT--GKKGSDEMGVMFLLVQVMGGRKLPLP 55
>11185
Length = 473
Score = 44.3 bits (103), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 35/142 (24%), Positives = 61/142 (42%), Gaps = 25/142 (17%)
Frame = +1
Query: 314 DMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYT-----AR 368
D + G+ YI + + DLR + +L+ + K ADFGL+++ +N A
Sbjct: 13 DFGIHLVTGLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAE 192
Query: 369 QGAKFPIK----------------WTAPEAALYGRFTIKSDVWSFGILLTELVTKGRV-- 410
G ++ I+ + APE +I SD+W+ G + E+ + R+
Sbjct: 193 AGDQWNIQSAEEMMKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSGSRLSA 372
Query: 411 -PYPG-MNNREVLEQVERGYRM 430
P P +N E L Q + R+
Sbjct: 373 KPSPEFLNLLESLLQKDSTRRL 438
>14257
Length = 919
Score = 42.4 bits (98), Expect = 5e-04, Method: Compositional matrix adjust.
Identities = 27/85 (31%), Positives = 45/85 (52%)
Frame = -3
Query: 147 EEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDWDDMKGDHVKHYKIR 206
EEWY GK+GRK+AE+ L G FL+RE+ + + LS R + +V+H +
Sbjct: 896 EEWYHGKIGRKEAEKLL----ELDGDFLVREASNSAAQFVLSGR-----QNGNVRHLLL- 747
Query: 207 KLDNGGYYITTRAQFETLQQLVQHY 231
+D G T F+++ L+ ++
Sbjct: 746 -VDPDGIVRTKDFIFDSVSHLINYH 675
>28638
Length = 1458
Score = 42.0 bits (97), Expect = 5e-04, Method: Compositional matrix adjust.
Identities = 35/109 (32%), Positives = 53/109 (48%), Gaps = 5/109 (4%)
Frame = -1
Query: 303 EGRALKLPNLVDMAAQVAAGMAYIE--RMNYIHRDLRSANILVGN---GLICKIADFGLA 357
EG +L L A Q+ + ++ MN IH DL+ NIL+ N I KI DFG +
Sbjct: 852 EGVSLNLTR--KFAQQLCTALLFLATPEMNIIHCDLKPENILLCNPKRSAI-KIVDFGSS 682
Query: 358 RLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVT 406
+ Y Q ++F + +PE L + + D+WS G +L E+ T
Sbjct: 681 CQLGQRIYQYIQ-SRF---YRSPEVLLGVPYDLAIDMWSLGCILVEMHT 547
>28095
Length = 597
Score = 41.6 bits (96), Expect = 7e-04, Method: Compositional matrix adjust.
Identities = 19/50 (38%), Positives = 28/50 (56%)
Frame = +3
Query: 89 ALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYV 138
A+YDY+A D++SF+ G+ + W R TG+ G +PSNYV
Sbjct: 270 AMYDYQAADSDEVSFNDGDTIIECQPVDAGWMTGRVERTGQYGMLPSNYV 419
>12786
Length = 460
Score = 41.2 bits (95), Expect = 9e-04, Method: Compositional matrix adjust.
Identities = 27/107 (25%), Positives = 51/107 (47%), Gaps = 21/107 (19%)
Frame = -3
Query: 332 IHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPI-KWTAPEAALYG---- 386
IH DL+ AN ++ G + K+ DFG+A ++ ++ + + ++ + +PEA +
Sbjct: 344 IHSDLKPANFMLVAGNL-KLIDFGIANTLQQDKTSVLKDSRVGTPSYMSPEAIMAACDDS 168
Query: 387 ----------------RFTIKSDVWSFGILLTELVTKGRVPYPGMNN 417
+ ++SDVWS G +L +V GR P+ + N
Sbjct: 167 ADDSMEEDGHRTKPKYKVGVRSDVWSLGCILYNMVY-GRTPFQHIKN 30
>26711
Length = 405
Score = 41.2 bits (95), Expect = 0.001, Method: Composition-based stats.
Identities = 31/111 (27%), Positives = 54/111 (48%), Gaps = 3/111 (2%)
Frame = -2
Query: 318 QVAAGMAYIERMNYIHRDLRSANILVGNGLI--CKIADFGLAR-LIEDNEYTARQGAKFP 374
QV + ++ +H DL+ +N+L+ + ++ DFGLAR L E G
Sbjct: 392 QVLDILQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARKLYPPQETFLNHGTP-- 219
Query: 375 IKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVE 425
+T+PEA + SDVW G+L L++ G+ P+ + E L++ +
Sbjct: 218 -GFTSPEALDVKPISTASDVWGVGVLAYILLS-GQSPFQADSATESLKKTQ 72
>05206
Length = 1075
Score = 41.2 bits (95), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 19/50 (38%), Positives = 27/50 (54%)
Frame = +1
Query: 89 ALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYV 138
ALY +EA E + + E+ QIL +GD W G G++PS+YV
Sbjct: 103 ALYPFEAMNEGSVPMGENEEMQILEEDQGDGWTRVRKADGSEGFVPSSYV 252
>01494
Length = 2122
Score = 40.8 bits (94), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 30/107 (28%), Positives = 49/107 (45%), Gaps = 5/107 (4%)
Frame = +3
Query: 89 ALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYVAPVDS---IQ 145
AL+DY A +D+LSF KG ++ +G WW + + PSN+V +++ +
Sbjct: 318 ALHDYNANRDDELSFCKGAIITNVSRQDGGWWRG-DYGAKKQHWFPSNFVEEIETHSDVN 494
Query: 146 AEEWYFGKL--GRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIR 190
++ G L G D + L+ PRG K A+ +S R
Sbjct: 495 SDSMPLGSLQQGSFDIQGCLVEPLAPRG---------DKSAFRISTR 608
>37602
Length = 804
Score = 40.8 bits (94), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 23/77 (29%), Positives = 37/77 (48%)
Frame = -1
Query: 278 VSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLR 337
+ E ++I EY GS+ D L P + + + G+ Y+ R +HRD++
Sbjct: 309 LRREKLWIAMEYCGGGSMQDIYH--VTGPLTEPQIAFVCRETLKGLHYLHRRGKMHRDIK 136
Query: 338 SANILVGNGLICKIADF 354
ANIL+ K+ADF
Sbjct: 135 GANILLTEEGDVKLADF 85
>32000
Length = 644
Score = 40.0 bits (92), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 29/85 (34%), Positives = 45/85 (52%), Gaps = 3/85 (3%)
Frame = -1
Query: 350 KIADFGLARL--IEDNEYTARQGAKFPIKWTAPEAALYGRF-TIKSDVWSFGILLTELVT 406
KIADFGLAR+ + YT + + APE L RF ++ D+WS G + E++T
Sbjct: 569 KIADFGLARVFGLPVRTYTHEV---ITLWYRAPEILLGCRFYSVPVDIWSLGCIFVEMMT 399
Query: 407 KGRVPYPGMNNREVLEQVERGYRMP 431
+ R +PG + + L ++ R P
Sbjct: 398 R-RALFPGDSEIDQLYRIFRTLGTP 327
>18481
Length = 437
Score = 39.7 bits (91), Expect = 0.003, Method: Composition-based stats.
Identities = 21/65 (32%), Positives = 37/65 (56%), Gaps = 3/65 (4%)
Frame = -1
Query: 305 RALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICK---IADFGLARLIE 361
R L ++ ++ Q+ + + +I + +IHRDL+ N L+G G C I DFGL++ +
Sbjct: 212 RRFTLKTILMVSDQLLSRLEFIHQKCFIHRDLKPDNFLMGLGRHCHRLYIIDFGLSKRYK 33
Query: 362 DNEYT 366
D + T
Sbjct: 32 DTQGT 18
>32264
Length = 287
Score = 39.3 bits (90), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 18/44 (40%), Positives = 29/44 (65%)
Frame = +1
Query: 424 VERGYRMPCPQDCPISLHELMIHCWKKDPEERPTFEYLQSFLED 467
+E GYR+ P S+++LM+ CW+ PE+RP F+ L + L+D
Sbjct: 1 IEDGYRLQQNPQTPDSVYKLMLRCWEYVPEKRPHFKELYTSLKD 132
>35671
Length = 567
Score = 38.5 bits (88), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 15/47 (31%), Positives = 28/47 (59%)
Frame = -3
Query: 425 ERGYRMPCPQDCPISLHELMIHCWKKDPEERPTFEYLQSFLEDYFTA 471
++G R+ P C +++M+ CW + EERPTF+ L +E+ + +
Sbjct: 565 QKGNRLAKPISCTDEAYKVMLQCWTESREERPTFKKLVPVMENLYRS 425
>16716
Length = 934
Score = 37.7 bits (86), Expect = 0.010, Method: Compositional matrix adjust.
Identities = 28/111 (25%), Positives = 44/111 (39%)
Frame = -1
Query: 28 YRYGTDPTPQHYPSFGVTSIPNYNNFHAAGGQGLTVFGGVNSSSHXXXXXXXXXXXXXXF 87
Y +P PQH P + + A Q GG +++
Sbjct: 577 YEVSEEPAPQHEPEESPYEMADEEPAAPAQSQP----GGGSTA----------------- 461
Query: 88 VALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYV 138
+ALYDY+A +D+L+F + + + WW R G+ G P+NYV
Sbjct: 460 IALYDYQAADDDELTFDPDDVITDIEMIDDGWW--RGSCHGKNGLFPANYV 314
>17286
Length = 489
Score = 37.7 bits (86), Expect = 0.011, Method: Compositional matrix adjust.
Identities = 17/56 (30%), Positives = 31/56 (55%)
Frame = +3
Query: 89 ALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYVAPVDSI 144
A+YD+ ++ +L F +G+ +++ + +W+E G+ GY P NYV V I
Sbjct: 36 AIYDFLPESDGELGFQEGDMITLISQVDENWFEGS--VHGKVGYFPINYVEVVVPI 197
>16708
Length = 1397
Score = 37.7 bits (86), Expect = 0.012, Method: Compositional matrix adjust.
Identities = 14/45 (31%), Positives = 27/45 (60%)
Frame = -1
Query: 315 MAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARL 359
+A Q + +I + +H D+++ N+LV CK+ D+G+A+L
Sbjct: 1079 IAGQXVCALEHIHELGVVHMDVKADNVLVDAHGNCKLTDYGIAQL 945
>30740
Length = 488
Score = 37.4 bits (85), Expect = 0.014, Method: Compositional matrix adjust.
Identities = 13/33 (39%), Positives = 21/33 (63%)
Frame = +2
Query: 91 YDYEARTEDDLSFHKGEKFQILNSSEGDWWEAR 123
YD+ R +DL F KG+ ++++ E +WW AR
Sbjct: 203 YDFSGRDPEDLPFSKGDILELISKDEEEWWTAR 301
>27405
Length = 532
Score = 37.0 bits (84), Expect = 0.017, Method: Compositional matrix adjust.
Identities = 32/121 (26%), Positives = 52/121 (42%)
Frame = -3
Query: 275 YAVVSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHR 334
YA + E + + + MN G L L + + AA+V G+ ++ ++R
Sbjct: 353 YAFQTPEKLCFILDLMNGGDLHYHLS--QHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYR 180
Query: 335 DLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDV 394
DL+ ANIL+ +I+D GLA + A G + APE + G+ S
Sbjct: 179 DLKPANILLDENGHVRISDLGLACDFSKKKPHASVGTH---GYMAPEVLMKGQAYDSSAD 9
Query: 395 W 395
W
Sbjct: 8 W 6
>38046
Length = 446
Score = 36.6 bits (83), Expect = 0.020, Method: Composition-based stats.
Identities = 15/26 (57%), Positives = 20/26 (76%)
Frame = -1
Query: 319 VAAGMAYIERMNYIHRDLRSANILVG 344
+A MAY+E+ N+IHR+L NILVG
Sbjct: 98 IADAMAYMEKENFIHRNLGDRNILVG 21
>06462
Length = 1511
Score = 36.2 bits (82), Expect = 0.033, Method: Compositional matrix adjust.
Identities = 27/99 (27%), Positives = 43/99 (43%)
Frame = +1
Query: 133 IPSNYVAPVDSIQAEEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDW 192
+PS+ D E WY GK+ R++AE+ L G FL+RES + LS +
Sbjct: 1048 MPSSETGVTDPPLHELWYHGKMSRREAEKLL----GKDGDFLVRESGHNXSQFVLSGK-- 1209
Query: 193 DDMKGDHVKHYKIRKLDNGGYYITTRAQFETLQQLVQHY 231
H + + +D G T F+ + LV ++
Sbjct: 1210 -----HHGQFIHLLLVDPDGIVRTKDYIFDNISHLVSYH 1311
>21433
Length = 590
Score = 35.8 bits (81), Expect = 0.044, Method: Compositional matrix adjust.
Identities = 25/89 (28%), Positives = 40/89 (44%)
Frame = +2
Query: 318 QVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKW 377
Q+++ + Y IHRD++ N+L+G KIADFG + + T G + +
Sbjct: 191 QLSSALEYCHYRKVIHRDIKPENLLLGLKGDLKIADFGWSVHAPSSRRTTMCGT---LDY 361
Query: 378 TAPEAALYGRFTIKSDVWSFGILLTELVT 406
PE D+WS G+L E +
Sbjct: 362 LPPEMVEGKTHDENVDLWSLGVLCYEFLV 448
>01392
Length = 1806
Score = 35.4 bits (80), Expect = 0.049, Method: Compositional matrix adjust.
Identities = 32/109 (29%), Positives = 51/109 (46%), Gaps = 12/109 (11%)
Frame = -1
Query: 318 QVAAGMAYIERMNYIHRDLRSANIL---VGNGLICKIADFGLARLIE-DNEYTARQGAKF 373
+A + ++ HRDL+ NIL + + + KI DF LA I D + T
Sbjct: 1767 HIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGISCDGDGTKTPELLT 1588
Query: 374 PI---KWTAPEA--ALYG---RFTIKSDVWSFGILLTELVTKGRVPYPG 414
P+ ++ APE A G + + D+WS GI+L ++ G P+ G
Sbjct: 1587 PVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILYIMLC-GYPPFYG 1444
>07933
Length = 728
Score = 35.0 bits (79), Expect = 0.061, Method: Compositional matrix adjust.
Identities = 13/30 (43%), Positives = 18/30 (60%)
Frame = +3
Query: 433 PQDCPISLHELMIHCWKKDPEERPTFEYLQ 462
P CP L+ +M+ CW +P RPTF L+
Sbjct: 3 PNYCPNLLYNIMMQCWSAEPSARPTFHKLE 92
>18881
Length = 762
Score = 35.0 bits (79), Expect = 0.062, Method: Compositional matrix adjust.
Identities = 22/65 (33%), Positives = 34/65 (52%), Gaps = 2/65 (3%)
Frame = -3
Query: 169 PRGTFLIRESETTKGAYSLSIRDWDDMK--GDHVKHYKIRKLDNGGYYITTRAQFETLQQ 226
P GTFLIR + T S R+ + V+H K+ + G +Y+ F+++QQ
Sbjct: 748 PDGTFLIRVTNT-------SARESCPQY*YANAVRHIKVNRNPQGRFYLADGHYFDSVQQ 590
Query: 227 LVQHY 231
LV+HY
Sbjct: 589 LVEHY 575
Score = 28.9 bits (63), Expect = 5.2, Method: Compositional matrix adjust.
Identities = 14/45 (31%), Positives = 22/45 (48%), Gaps = 2/45 (4%)
Frame = -3
Query: 101 LSFHKGEKFQIL--NSSEGDWWEARSLTTGETGYIPSNYVAPVDS 143
++ ++ IL N + WW+ +L T + GY P YV DS
Sbjct: 436 VTLKLNDRISILSKNGQDKGWWKGENLRTKKVGYFPLAYVDEEDS 302
>13664
Length = 507
Score = 35.0 bits (79), Expect = 0.064, Method: Compositional matrix adjust.
Identities = 16/45 (35%), Positives = 25/45 (55%)
Frame = +2
Query: 88 VALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGY 132
VALYDY+A+ D+L+ G+ +L+ WW L G+ G+
Sbjct: 374 VALYDYKAQRSDELTILSGDVIMLLHKDSESWWMGE-LLDGQQGF 505
>31789
Length = 676
Score = 34.3 bits (77), Expect = 0.13, Method: Compositional matrix adjust.
Identities = 22/76 (28%), Positives = 40/76 (52%), Gaps = 6/76 (7%)
Frame = +2
Query: 254 ESFLEEAQIMKKLKHDKLVQLYAVVSE------EPIYIVTEYMNKGSLLDFLKDGEGRAL 307
+ F EEA+++K+L+H +V+ + E + I +VTE M G+L +LK + +
Sbjct: 452 QRFKEEAEMLKELQHPNIVRFFDYWEEHNHRNRKVIILVTELMTSGTLKTYLK--RFKKI 625
Query: 308 KLPNLVDMAAQVAAGM 323
L L + Q+ G+
Sbjct: 626 NLKVLKNWCRQILKGL 673
>02638
Length = 1490
Score = 33.9 bits (76), Expect = 0.14, Method: Compositional matrix adjust.
Identities = 25/103 (24%), Positives = 49/103 (47%), Gaps = 7/103 (6%)
Frame = +1
Query: 375 IKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRM---- 430
I + APE + DVWS G ++ E+ T R P+ N+ ++ + +++
Sbjct: 28 IAFMAPEVLRGESYGRACDVWSVGCVMIEMCT-CRPPW---NSHDISNHLALIFKIASSV 195
Query: 431 ---PCPQDCPISLHELMIHCWKKDPEERPTFEYLQSFLEDYFT 470
P P++ + +LM+ C ++D + RP+ + L + FT
Sbjct: 196 DPPPIPENMSPPVRDLMLRCLEQDSDFRPSAKDL--LMHPLFT 318
>29360
Length = 363
Score = 33.9 bits (76), Expect = 0.16, Method: Composition-based stats.
Identities = 28/116 (24%), Positives = 50/116 (43%), Gaps = 7/116 (6%)
Frame = +3
Query: 235 WNGNTK--VAIKTLKPGTMSPESFLEEAQIMKKLKHD-----KLVQLYAVVSEEPIYIVT 287
W T VAIK LK E I+++L + V+ + + +
Sbjct: 12 WKKGTSEIVAIKILKNHPSYARQGQIEVSILQRLSQESADDYNFVRAFECFQHKNHTCLV 191
Query: 288 EYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILV 343
M + +L DFLK + + L L + + QV + ++++ IH DL+ NI++
Sbjct: 192 FEMLEQNLYDFLKQNKFQPLPLKYIRPITQQVLTALRKLKQLGLIHADLKPENIML 359
>37260
Length = 401
Score = 33.5 bits (75), Expect = 0.18, Method: Composition-based stats.
Identities = 17/56 (30%), Positives = 30/56 (53%)
Frame = -1
Query: 149 WYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDWDDMKGDHVKHYK 204
WY+G L ++AE +L+ G+FL+R+S SLS + + ++H+K
Sbjct: 182 WYWGPLSYEEAESKLMD--KRDGSFLVRDSSNENYILSLSFKSMGHVHHTRIEHHK 21
>00394
Length = 548
Score = 32.0 bits (71), Expect = 0.55, Method: Compositional matrix adjust.
Identities = 18/53 (33%), Positives = 31/53 (58%), Gaps = 6/53 (11%)
Frame = -2
Query: 254 ESFLEEAQIMKKLKHDKLVQLYAVVSE------EPIYIVTEYMNKGSLLDFLK 300
+ F EEA+++K+L+H +V+ + E + I +VTE M G+L +LK
Sbjct: 166 QRFKEEAEMLKELQHPNIVRFFDYWEEHNHRNRKVIILVTELMTSGTLKTYLK 8
>18401
Length = 463
Score = 31.6 bits (70), Expect = 0.82, Method: Compositional matrix adjust.
Identities = 18/50 (36%), Positives = 27/50 (54%)
Frame = -3
Query: 377 WTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVER 426
+ APE L ++ DVWS G ++ EL T G + +N+E L +ER
Sbjct: 434 YRAPEVILELGWSHPCDVWSVGCIMFELYT-GYTLFQTHDNKEHLAMMER 288
>17516
Length = 453
Score = 31.2 bits (69), Expect = 0.87, Method: Compositional matrix adjust.
Identities = 28/101 (27%), Positives = 47/101 (46%), Gaps = 6/101 (5%)
Frame = -3
Query: 379 APEAALY-GRFTIKSDVWSFGILLTELVTKGRVPYPGMNNR---EVLEQVERGYRMPCPQ 434
APE L G++ +K+DV+S I+L EL G+ +++ + + V+ G R
Sbjct: 415 APEVLLQKGQYDMKADVYSLAIILWEL-WYGQDAADHISSHLFGRLEDAVQAGLRPSVTM 239
Query: 435 DC--PISLHELMIHCWKKDPEERPTFEYLQSFLEDYFTATE 473
C P +L+ W+ +RPT F ED+ T+
Sbjct: 238 TCKPPDDWLKLLQSGWEFHASKRPTSRDAAEFFEDFLERTK 116
>13641
Length = 2081
Score = 31.2 bits (69), Expect = 1.0, Method: Compositional matrix adjust.
Identities = 15/58 (25%), Positives = 28/58 (48%), Gaps = 9/58 (15%)
Frame = +2
Query: 89 ALYDYEARTEDD-------LSFHKGEKFQILNSSEGDWWEA--RSLTTGETGYIPSNY 137
A++ + ++ +D+ LSF +G+ I+N + WW+A G IPS +
Sbjct: 164 AMFSFNSKLDDNIPCKEAGLSFQQGDILHIVNQEDAIWWQAYKHGDAKKRAGLIPSRH 337
>27287
Length = 514
Score = 30.8 bits (68), Expect = 1.2, Method: Compositional matrix adjust.
Identities = 11/30 (36%), Positives = 19/30 (63%)
Frame = -2
Query: 443 LMIHCWKKDPEERPTFEYLQSFLEDYFTAT 472
+M CW++DP +RP+F L L+ T++
Sbjct: 474 IMHSCWQEDPNDRPSFSRLVQELDKMLTSS 385
>23319
Length = 2235
Score = 30.8 bits (68), Expect = 1.3, Method: Compositional matrix adjust.
Identities = 12/45 (26%), Positives = 24/45 (53%)
Frame = +3
Query: 380 PEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQV 424
P+ ++ D+WS G + EL GR +PG ++ + L+++
Sbjct: 3 PDVYXAKMYSTSIDMWSAGCIFAELANAGRPLFPGNDDDDQLKRI 137
>29590
Length = 320
Score = 30.4 bits (67), Expect = 1.9, Method: Composition-based stats.
Identities = 13/43 (30%), Positives = 26/43 (60%)
Frame = +3
Query: 377 WTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNRE 419
+ APE Y +I++D+WS G+L ++T P+ G+ +++
Sbjct: 72 YVAPEVLDYEPLSIQTDMWSLGVLSYVMLTACS-PFVGITSKK 197
>36481
Length = 806
Score = 29.6 bits (65), Expect = 2.5, Method: Compositional matrix adjust.
Identities = 26/108 (24%), Positives = 48/108 (44%), Gaps = 6/108 (5%)
Frame = +2
Query: 241 VAIKTLKPGTMSPESFLEEAQIMKKLK----HDK--LVQLYAVVSEEPIYIVTEYMNKGS 294
+A+K +K E+ E +++KL+ H K VQ+ ++ +M S
Sbjct: 446 IALKIIKNVDKYREAAKLEINVLEKLREKDPHAKHMCVQMLDWFDYHGHVCISFHMLGLS 625
Query: 295 LLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANIL 342
+ DFLKD A + + ++ Q+ + ++ H DL+ NIL
Sbjct: 626 VFDFLKDNSYGAYPIEQVRHISYQLCYAVNFLHENQLTHTDLKPENIL 769
>27562
Length = 399
Score = 29.3 bits (64), Expect = 3.3, Method: Composition-based stats.
Identities = 18/54 (33%), Positives = 26/54 (48%), Gaps = 3/54 (5%)
Frame = -1
Query: 418 REVLEQVERGYRMPCPQDCPISLHELMIH-CWKKDPEERPT--FEYLQSFLEDY 468
R + Q+ R P+ C SL E++ WKKDP ER E L F++ +
Sbjct: 222 RVLWTQMRRRGTQIQPRPCSSSLFEIL*ETAWKKDPSERTENDIEILMDFMQHF 61
>18050
Length = 448
Score = 28.5 bits (62), Expect = 6.4, Method: Composition-based stats.
Identities = 12/56 (21%), Positives = 24/56 (42%)
Frame = +3
Query: 88 VALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYVAPVDS 143
+A + YE+ D L G+ + W++ + G G+ P +Y ++S
Sbjct: 27 IAKHSYESDEPDVLQLELGDVVNVSRKLPDGWYQGERIRDGAVGWFPGSYTEELNS 194
>15741
Length = 402
Score = 28.5 bits (62), Expect = 7.0, Method: Composition-based stats.
Identities = 11/32 (34%), Positives = 18/32 (56%)
Frame = -3
Query: 311 NLVDMAAQVAAGMAYIERMNYIHRDLRSANIL 342
+ A VA GMA++ +HRD+ + N+L
Sbjct: 97 DFFSFALHVARGMAHVANNKIVHRDVAARNVL 2
>18663
Length = 600
Score = 28.1 bits (61), Expect = 7.2, Method: Compositional matrix adjust.
Identities = 20/65 (30%), Positives = 30/65 (46%), Gaps = 10/65 (15%)
Frame = +2
Query: 377 WTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPY--------PGMNNREVLEQV--ER 426
+ APE + D W+ G+LL E++ GR P+ P N + L QV E+
Sbjct: 26 YIAPEILRGEDYGFSVDWWALGVLLYEMLA-GRSPFDIAGASENPDQNTEDYLFQVILEK 202
Query: 427 GYRMP 431
R+P
Sbjct: 203 TIRIP 217
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000229470 | hsapiens_gene_ensembl | Proto-oncogene
tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn) (Protooncogene
Syn) (SLK). [Source:Uniprot/SWISSPROT;Acc:P06241]
(485 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
21808 318 7e-88
06405 300 1e-81
11780 170 2e-62
09007 153 1e-37
04852 147 6e-36
17300 123 2e-33
20640 125 4e-29
07291 122 2e-28
14116 121 5e-28
08294 104 8e-23
07940 102 5e-22
18996 98 6e-21
22005 83 2e-20
01718 94 9e-20
17637 93 2e-19
13592 91 1e-18
14477 86 3e-17
13305 80 2e-15
19301 79 4e-15
01756 77 2e-14
00715 77 2e-14
12721 72 7e-13
17253 70 3e-12
01060 70 3e-12
01707 68 7e-12
18921 67 1e-11
29581 66 4e-11
14126 65 9e-11
00300 64 1e-10
25550 64 2e-10
18484 63 2e-10
14420 62 6e-10
27546 61 1e-09
04591 60 1e-09
00392 59 6e-09
01966 58 7e-09
31885 57 2e-08
13066 57 2e-08
07836 57 2e-08
09606 55 7e-08
03240 55 8e-08
12672 54 1e-07
13212 53 3e-07
04138 52 4e-07
21079 52 7e-07
19094 49 6e-06
29243 49 6e-06
15910 48 1e-05
30755 47 1e-05
26560 46 3e-05
21210 46 4e-05
19761 45 6e-05
11185 45 1e-04
14257 44 1e-04
01106 43 2e-04
28638 42 5e-04
26711 42 8e-04
12786 41 0.001
37602 40 0.001
18481 40 0.003
32000 40 0.003
32264 40 0.003
16708 39 0.004
35671 39 0.006
00394 38 0.009
27405 38 0.010
38046 37 0.020
31789 36 0.031
21433 36 0.038
11228 36 0.038
01392 36 0.042
18881 35 0.056
07933 35 0.062
37260 34 0.13
02638 34 0.14
29360 33 0.18
06462 33 0.21
24983 32 0.46
17516 32 0.78
18401 31 1.1
23319 31 1.2
27287 31 1.3
29590 30 1.9
36481 30 2.4
27562 29 3.5
18663 28 6.4
15741 28 7.1
>21808
Length = 1011
Score = 318 bits (814), Expect(2) = 7e-88, Method: Compositional matrix adjust.
Identities = 152/225 (67%), Positives = 180/225 (80%), Gaps = 1/225 (0%)
Frame = +1
Query: 236 GTWNGNTKVAIKTLKPGTMSPESFLEEAQIMKKLKHDKLVQLYAVVSEE-PIYIVTEYMN 294
G WN T VAIKTLK GTM P+ FL EAQIMKKL+H KL+QLYAV +++ PI+I+TE M
Sbjct: 4 GLWNNTTPVAIKTLKSGTMDPKDFLAEAQIMKKLRHPKLIQLYAVCTQDDPIFIITELMK 183
Query: 295 KGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKI 354
GSLL+FL+ G+GR LKLP L+D+ AQ+A GMAY+E NYIHRDL + NILV + KI
Sbjct: 184 NGSLLEFLQ-GKGRVLKLPALIDIGAQIACGMAYLESQNYIHRDLAARNILVSDNNTVKI 360
Query: 355 ADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVP 414
ADFGLAR+I+++EY AR GA+FPIKWTAPEAA Y RFTIKSDVWSFGILLTE VT GRVP
Sbjct: 361 ADFGLARVIKEDEYEARVGARFPIKWTAPEAANYNRFTIKSDVWSFGILLTETVTYGRVP 540
Query: 415 YPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKKDPEERP 459
YPGM N EVL QVE GYRMPCP CP L+++M+ CW+K+ ERP
Sbjct: 541 YPGMTNAEVLHQVEHGYRMPCPPGCPKPLYDIMLECWRKEEMERP 675
Score = 25.0 bits (53), Expect(2) = 7e-88, Method: Compositional matrix adjust.
Identities = 11/22 (50%), Positives = 14/22 (63%)
Frame = +2
Query: 459 PTFEYLQSFLEDYFTATEPQYQ 480
PTFE LQ LE++FT Y+
Sbjct: 674 PTFETLQWKLEEFFTMDSKDYR 739
>06405
Length = 1965
Score = 300 bits (767), Expect = 1e-81, Method: Compositional matrix adjust.
Identities = 160/350 (45%), Positives = 221/350 (63%), Gaps = 5/350 (1%)
Frame = +1
Query: 128 ESETTKGAYSLSIRDWDDMKGDHVKHYKIRKLDNGGYYITTRAQFETLQQLVQHYSEKAD 187
ESE++ G S+S+R +G V HY+I + D+G ++T +F TL +LV H+S AD
Sbjct: 1 ESESSPGQRSISVR----FEG-RVYHYRITE-DDGKVFVTQEHRFNTLAELVHHHSIHAD 162
Query: 188 GLCFNLTVIASS-CTPQTSGLAK--DAWEVARRSLCLEKKLGQGCFAEVWLGTWNG-NTK 243
GL L A P G++ D WE+ R + ++ +LG G + +V+ W N
Sbjct: 163 GLVTTLLYPAPKRQKPTVFGVSPEPDRWEIERTEIAMKHRLGGGQYGDVYEAMWKRYNKI 342
Query: 244 VAIKTLKPGTMSPESFLEEAQIMKKLKHDKLVQLYAVVSEEP-IYIVTEYMNKGSLLDFL 302
VA+KTLK TM+ FLEEA IMK++KH LVQL V + EP YIVTE+M G+LLD+L
Sbjct: 343 VAVKTLKEDTMALNDFLEEAAIMKEMKHPNLVQLLGVCTREPPFYIVTEFMPHGNLLDYL 522
Query: 303 KDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARL 362
+ L+ MA Q+A+GMAY+E N+IHRDL + N LV + + K+ADFGLARL
Sbjct: 523 RSSTREENGPTALMYMATQIASGMAYLETKNFIHRDLAARNCLVADSNMVKVADFGLARL 702
Query: 363 IEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNRE 422
++D+ YTA GAKFPIKWTAPE + RF+ +SD+W+FG+LL EL T G PYPG+ E
Sbjct: 703 MKDDTYTAHIGAKFPIKWTAPEGLAFNRFSTRSDIWAFGVLLWELATYGMSPYPGVELTE 882
Query: 423 VLEQVERGYRMPCPQDCPISLHELMIHCWKKDPEERPTFEYLQSFLEDYF 472
V +ERGYRM P P ++ LM+ CW+ DP++RPTF+ + LE+ F
Sbjct: 883 VYHLLERGYRMERPPGTPADVYILMLKCWQWDPKDRPTFKEIHFLLENMF 1032
>11780
Length = 1713
Score = 170 bits (431), Expect(2) = 2e-62, Method: Compositional matrix adjust.
Identities = 107/293 (36%), Positives = 156/293 (53%), Gaps = 7/293 (2%)
Frame = +3
Query: 100 WYFGKLGRKDAERQLLSFGNPR--GTFLIRESETTKGAYSLSIRDWDDMKGDHVKHYKIR 157
W+ GK+ R+ AE L PR G FLIRES G Y+L + V+HY+I
Sbjct: 255 WFHGKITRQQAEELL----KPREDGLFLIRESSNYPGDYTLCV-----CHLGKVEHYRIL 407
Query: 158 KLDNGGYYITTRAQFETLQQLVQHYSEKADGLCFNLTVIASS-----CTPQTSGLAKDAW 212
+N I F L +LV+HY ADGLC LT + T W
Sbjct: 408 YRENQ-LTIDEEGFFRNLDELVKHYLADADGLCTQLTRPVTKQGGNFGTVSLQEFKSGGW 584
Query: 213 EVARRSLCLEKKLGQGCFAEVWLGTWNGNTKVAIKTLKPGTMSPESFLEEAQIMKKLKHD 272
+A + L + + +G+G F +V+ G + G VAIK LK +SFL+EA +M L+HD
Sbjct: 585 VIAXQDLEIGEAIGKGDFGDVYKGMYRGQP-VAIKQLKDKDRGEQSFLQEASVMTSLRHD 761
Query: 273 KLVQLYAVVSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERM 332
LV+L VV E I++VTE+M KG+L+++L+ + + ++ A A M Y+E
Sbjct: 762 NLVRLIGVVLGETIFLVTEFMGKGNLVEYLRSRGRSVITKKDQINFATDTCAAMEYLESK 941
Query: 333 NYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEA 385
+HRDL + N+LV + K++DFGLA+ + ++ + KFPIKWTAPEA
Sbjct: 942 RLVHRDLAARNVLVHDDGKAKVSDFGLAKFGDFSQTS----VKFPIKWTAPEA 1088
Score = 87.0 bits (214), Expect(2) = 2e-62, Method: Compositional matrix adjust.
Identities = 41/86 (47%), Positives = 57/86 (66%)
Frame = +1
Query: 390 RFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIH 449
+FT KSD+WSFGILL E+ + GRVPYP + +V+ VERGYRM P+ CP ++ +M
Sbjct: 1102 KFTSKSDMWSFGILLWEIYSFGRVPYPRIPLTDVVMHVERGYRMEAPEGCPPEIYSIMKQ 1281
Query: 450 CWKKDPEERPTFEYLQSFLEDYFTAT 475
W+ DP ERPTF+ + + L + T
Sbjct: 1282 AWELDPNERPTFKSVLARLNNQRAVT 1359
>09007
Length = 1440
Score = 153 bits (387), Expect = 1e-37, Method: Compositional matrix adjust.
Identities = 97/283 (34%), Positives = 151/283 (53%), Gaps = 15/283 (5%)
Frame = -1
Query: 214 VARRSLCLEKKLGQGCFAEVWLGTWNGNT----KVAIKTLKPGTMSP--ESFLEEAQIMK 267
+++ + L K LGQG F V W + +VA+K L + + FL+E IM+
Sbjct: 888 ISKDCVALSKSLGQGHFGTVRQAIWTAESGEKVQVAVKCLSKDKIHKDGQEFLKETAIMQ 709
Query: 268 KLKHDKLVQLYAVVSEE--PIYIVTEYMNKGSLLDFLKDGEGRA-LKLPNLVDMAAQVAA 324
L H+ +V++Y VV + I +VTE SLL+ +K+ R +P L D + QV
Sbjct: 708 MLDHENIVRVYGVVMDNGADIMLVTELAPMRSLLECVKEVSARVDFSVPRLCDFSQQVCD 529
Query: 325 GMAYIERMNYIHRDLRSANILVGNGLICKIADFGLA-RLIEDNEYTARQGA---KFPIKW 380
GM+Y+E +HRDL + NIL+ + KI+D G++ L EY Q + + W
Sbjct: 528 GMSYLESKRLVHRDLAARNILLFSKSKVKISDVGVSGALGAGKEYYQSQQTIHLQNAVAW 349
Query: 381 TAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVE--RGYRMPCPQD 438
APE+ F+ SDVW+FG+LL E T G P+ G+N ++++E V+ + R+ P
Sbjct: 348 CAPESFRNLCFSSASDVWAFGVLLWEFFTHGFQPWAGLNGQQIMEAVDAPQSQRLEQPDL 169
Query: 439 CPISLHELMIHCWKKDPEERPTFEYLQSFLEDYFTATEPQYQP 481
CP + +M+ CW+++P+ RPTF L FL T PQ +P
Sbjct: 168 CPKEYYAVMLKCWEQEPQRRPTFSQL--FL------TLPQIRP 64
>04852
Length = 1462
Score = 147 bits (372), Expect = 6e-36, Method: Compositional matrix adjust.
Identities = 87/259 (33%), Positives = 136/259 (52%), Gaps = 31/259 (11%)
Frame = +1
Query: 242 TKVAIKTLKPGTMSPE--SFLEEAQIMKKLK----HDKLVQLYAVVSEE-PIYIVTEYMN 294
+ VA+K L+ + E F++E Q+MK +K H +V ++ P++++ E+
Sbjct: 22 STVAVKMLRDIVTAVEEQDFVQELQVMKAVKKMGSHINIVNFLGCCTQGGPLWVIVEFAK 201
Query: 295 KGSLLDFL---KDG--------------------EGRALKLPNLVDMAAQVAAGMAYIER 331
G+L DFL +DG G ++ NL+ A Q+A GM ++
Sbjct: 202 NGNLRDFLESCRDGINGYGKFVSPQDPGWYTKTPGGHVIRRKNLLSYAFQIARGMEFLAS 381
Query: 332 MNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRF 391
IHRDL + N+LV + KIADFGL+R + Y R G + P+KW APEA R+
Sbjct: 382 RKCIHRDLAARNVLVTEEHVLKIADFGLSR--TGDYYKKRSGGRLPVKWMAPEALFDMRY 555
Query: 392 TIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQ-VERGYRMPCPQDCPISLHELMIHC 450
T KSDVWSFG++L E+ + G +PY + N E+ + ++ YRMP P+ +L+ +M C
Sbjct: 556 TTKSDVWSFGVVLWEIFSLGGMPYASIPNEELYSKLLDDAYRMPRPELASGNLYAIMERC 735
Query: 451 WKKDPEERPTFEYLQSFLE 469
W P +RP F L ++
Sbjct: 736 WLNRPSDRPEFSQLVGHID 792
>17300
Length = 480
Score = 123 bits (308), Expect(2) = 2e-33, Method: Compositional matrix adjust.
Identities = 56/117 (47%), Positives = 83/117 (70%), Gaps = 4/117 (3%)
Frame = +1
Query: 322 VAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDN----EYTARQGAKFP 377
+++GM + M Y+HRDL + NILV L+CK+ADFGL+R IE + YT + G K P
Sbjct: 1 ISSGMGXLADMGYVHRDLAARNILVNEILVCKVADFGLSREIESDTTEGAYTTK-GGKIP 177
Query: 378 IKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMP 434
++WTAPEA Y +FT SDVWSFG+++ E+++ G PY +N++V++ VE+GYR+P
Sbjct: 178 VRWTAPEAIAYRKFTSASDVWSFGVVMWEVMSYGERPYWNWSNQDVIKAVEKGYRLP 348
Score = 37.7 bits (86), Expect(2) = 2e-33, Method: Composition-based stats.
Identities = 16/43 (37%), Positives = 23/43 (53%), Gaps = 1/43 (2%)
Frame = +2
Query: 435 CPQ-DCPISLHELMIHCWKKDPEERPTFEYLQSFLEDYFTATE 476
CP DCP +LH+LM+ W+K+ RP + L+ A E
Sbjct: 344 CPSMDCPEALHQLMLDAWQKERSHRPKMSMVVKTLDKLIRAPE 472
>20640
Length = 1492
Score = 125 bits (313), Expect = 4e-29, Method: Compositional matrix adjust.
Identities = 59/144 (40%), Positives = 86/144 (59%), Gaps = 1/144 (0%)
Frame = +1
Query: 334 YIHRDLRSANILVGNGLICKIADFGLARLIED-NEYTARQGAKFPIKWTAPEAALYGRFT 392
Y+HRDL + N LVG+ L+ KI+DFGLAR + + Y + PI+W EA LY +F+
Sbjct: 7 YVHRDLATRNCLVGHDLVVKISDFGLARSVHSVDYYRGSEHDAIPIRWMPLEAILYNKFS 186
Query: 393 IKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWK 452
+SDVWSFG++L E+ PY G+ + EV+ V+ G + CP+ P ++ELM CW
Sbjct: 187 TQSDVWSFGVVLWEIFAFALQPYYGLTHEEVVRFVKEGKVLACPERTPPPMYELMKQCWH 366
Query: 453 KDPEERPTFEYLQSFLEDYFTATE 476
+ P RP+F L LE+ + E
Sbjct: 367 RRPATRPSFHTLHKTLENMHSKYE 438
>07291
Length = 833
Score = 122 bits (307), Expect = 2e-28, Method: Compositional matrix adjust.
Identities = 60/167 (35%), Positives = 98/167 (58%), Gaps = 2/167 (1%)
Frame = +1
Query: 307 GRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLA-RLIED 365
+ L + L+D Q+A GMAY++ + +HR+L + N +V +++D+G+ L
Sbjct: 31 SKMLTVVQLLDFGRQIADGMAYLQEVKVVHRNLAARNCIVTEDGRLQLSDYGVTGSLFPQ 210
Query: 366 NEYTARQG-AKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVL 424
+ YTA A+ +KW APE F+ KSDVW+FG++L EL+T+G PYP + N +L
Sbjct: 211 SYYTADDSPARDLVKWMAPETIDNFHFSSKSDVWAFGVVLWELLTRGITPYPDVENSSLL 390
Query: 425 EQVERGYRMPCPQDCPISLHELMIHCWKKDPEERPTFEYLQSFLEDY 471
++ G+RM P+ P ++E+M CW + PE+RP F L L+ +
Sbjct: 391 PYLKEGHRMKKPKQSPEPVYEMMTACWNESPEQRPDFAELNDQLKTF 531
>14116
Length = 1017
Score = 121 bits (304), Expect = 5e-28, Method: Compositional matrix adjust.
Identities = 72/216 (33%), Positives = 120/216 (55%), Gaps = 13/216 (6%)
Frame = -1
Query: 214 VARRSLCLEKKLGQGCFAEVWLGTWN-----GNTKVAIKTL---KPGTMSPESFLEEAQI 265
+ R L + +++G+G F V G G+ VA+KTL P + +SFL+EA I
Sbjct: 645 IDREFLTMGEEIGKGNFGCVKRGFLTLPEQKGDILVAVKTLHNNNPREIELQSFLQEALI 466
Query: 266 MKKLKHDKLVQLYAV---VSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQV 322
MK H ++ L + + + P+ +V +M G LL +++D + + + +L+ +
Sbjct: 465 MKDFHHSNVLTLIGICLNLDDMPL-VVLPFMKHGDLLTYIRDDQHQP-TIKDLIMYGVDI 292
Query: 323 AAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQG--AKFPIKW 380
A GM Y+ + ++HRDL + N ++ K+ADFGLAR I + EY + + AK P+KW
Sbjct: 291 ARGMDYLAGLKFVHRDLAARNCMLDEDFHVKVADFGLARDIYEKEYYSSENKKAKLPVKW 112
Query: 381 TAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYP 416
A E+ G + K+DVWS+G++L EL+T+G P
Sbjct: 111 MALESLEKGNYDSKTDVWSYGVVLWELLTRGSDALP 4
>08294
Length = 1849
Score = 104 bits (259), Expect = 8e-23, Method: Compositional matrix adjust.
Identities = 64/207 (30%), Positives = 100/207 (48%), Gaps = 11/207 (5%)
Frame = +2
Query: 273 KLVQLYAVVSE-EPIYIVTEYMNKGSLLDFL-----KDGEGRALKLPNL-----VDMAAQ 321
+V V E EP +++TEY + G L FL +G GR ++P L + M Q
Sbjct: 890 NIVHFMGVCREAEPHFLITEYCDWGDLKQFLLATRNDNGRGRGTRVPALALSQKLGMGQQ 1069
Query: 322 VAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWT 381
VAAGM + +H DL + N+L+ + + K+A L+ + +EY P++W
Sbjct: 1070 VAAGMEALSNQGLVHGDLAARNVLLTSRMQLKVARPALSGDVYASEYYPLHQRLVPLRWL 1249
Query: 382 APEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPI 441
PE L T DVW+FG+ L E++ +PY M++ EVL ++ D P
Sbjct: 1250 PPEGVLEDSATTCGDVWAFGVFLWEVLQLADLPYRLMSDEEVLRSLQHSQAALDSPDAPP 1429
Query: 442 SLHELMIHCWKKDPEERPTFEYLQSFL 468
+L L+ C + P +RP F + S L
Sbjct: 1430 ALLSLLQRCTAQQPSQRPPFSEICSVL 1510
>07940
Length = 1336
Score = 102 bits (253), Expect = 5e-22, Method: Compositional matrix adjust.
Identities = 79/277 (28%), Positives = 117/277 (42%), Gaps = 70/277 (25%)
Frame = -3
Query: 212 WEVARRSLCLEKKLGQGCFAEVWLGTW------NGNTKVAIKTLKPGTMSPE--SFLEEA 263
WE R L L +LG+G F V G N + VA+K LK E + E
Sbjct: 857 WEFPRERLVLGDRLGEGAFGLVMKGEAMGIFKDNNSVTVAVKMLKEDATDREMMDLIREM 678
Query: 264 QIMKKL-KHDKLVQ----------LYAVVSEEPIYIVTEYMN------------------ 294
++MK + KH ++ LY +V P + +++
Sbjct: 677 EMMKVIGKHKNIINLLGCCTQRGALYVIVEFAPHGNLRDFLKSHRPHGTSYSCIADYEQP 498
Query: 295 -------------------KGSLLDFL-------------KDGEGRALKLPNLVDMAAQV 322
+G+ L F+ + + L +L+ A QV
Sbjct: 497 VITSSSSSFSHPNSASSSAQGTSLGFIPGTSTVSFSTGSHRQDMLKMLTPKDLISYAYQV 318
Query: 323 AAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQ-GAKFPIKWT 381
A GM Y+ IHRDL + N+LV + KIADFGL R ++ +Y + + P+KW
Sbjct: 317 ARGMEYLASKQCIHRDLAARNVLVAEEYVLKIADFGLTRNLQQFDYYRKTTDGRLPVKWM 138
Query: 382 APEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGM 418
APEA ++T KSDVWS+G+LL E+ T G PYP +
Sbjct: 137 APEALFDRKYTSKSDVWSYGVLLWEIFTLGGNPYPSV 27
>18996
Length = 491
Score = 98.2 bits (243), Expect = 6e-21, Method: Compositional matrix adjust.
Identities = 55/136 (40%), Positives = 79/136 (58%), Gaps = 6/136 (4%)
Frame = +2
Query: 335 IHRDLRSANILVGNGLICKIADFGLARLIE-DNEYTARQGAKFPIKWTAPEAALYGRFTI 393
IHRDL + NILV + KI+DFGLA+ D Y PIKW +PEA +F+
Sbjct: 2 IHRDLAARNILVDRSCV-KISDFGLAQFANADGYYYGISQRDIPIKWYSPEAIETCKFSS 178
Query: 394 KSDVWSFGILLTELVTKGRVP--YPG--MNNREVLEQVERGYRMPCPQDCPISLH-ELMI 448
SDVWS+G+ L E+ ++G +P PG + E L ++ +G R+P P+ C ++ ELM
Sbjct: 179 YSDVWSYGVTLFEMFSRGEIPNLLPGHDLTQEEFLNRLRKGERLPKPELCSDFVYSELMR 358
Query: 449 HCWKKDPEERPTFEYL 464
CW + P+ RPTF +
Sbjct: 359 PCWHEMPKSRPTFHQI 406
>22005
Length = 873
Score = 82.8 bits (203), Expect(2) = 2e-20, Method: Compositional matrix adjust.
Identities = 58/194 (29%), Positives = 91/194 (46%), Gaps = 44/194 (22%)
Frame = +1
Query: 259 FLEEAQIMKKLKHDKLVQLYAVVS-EEPIYIVTEYMNKGSLLDFLKDGEGRALKLP---- 313
F EA +M H +V+L V + +P+ ++ E+M+KG L DFL+ LP
Sbjct: 151 FEREASLMADFDHPNIVKLLGVCAIGKPMCLLFEFMSKGDLNDFLRLCSPENYNLPVSRS 330
Query: 314 -NLVD-------------------------------------MAAQVAAGMAYIERMNYI 335
NLV ++ Q++AGMAY+ + +Y+
Sbjct: 331 QNLVVDLEDGLRVEVEAEECEKDTQSEDRDCSGMLXTKDQLYISQQISAGMAYLAQKDYV 510
Query: 336 HRDLRSANILVGNGLICKIADFGLARLIEDNEY-TARQGAKFPIKWTAPEAALYGRFTIK 394
HRDL + + I+DFGLAR + +Y + PI+W EA LY +F+ +
Sbjct: 511 HRDL-ATRTVXSRTT*S*ISDFGLARSVHSVDYYRGSEQDAIPIRWMPLEAILYSKFSTQ 687
Query: 395 SDVWSFGILLTELV 408
SDVWSFG++L E++
Sbjct: 688 SDVWSFGVVLWEIL 729
Score = 34.3 bits (77), Expect(2) = 2e-20, Method: Compositional matrix adjust.
Identities = 15/42 (35%), Positives = 24/42 (57%)
Frame = +3
Query: 414 PYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKKDP 455
PY G+ + EV+ V+ G + P P ++ELM CW++ P
Sbjct: 744 PYYGLTHEEVVNYVKAGKILEQPTKTPHQVYELMKQCWQRRP 869
>01718
Length = 959
Score = 94.4 bits (233), Expect = 9e-20, Method: Compositional matrix adjust.
Identities = 81/266 (30%), Positives = 130/266 (48%), Gaps = 16/266 (6%)
Frame = +3
Query: 223 KKLGQGCFAEVWLGTWNGNTKVAIKTLKPGTMSPESFLEEAQIMKKLKHDKLVQLYAV-V 281
+K+G G F+EV+ T +V + T + + L E Q++ +L+H +++ V V
Sbjct: 165 EKIGAGFFSEVFKVTHRITGQVMALKMNTMTSNRHNMLREVQLLNRLQHANILRFMGVCV 344
Query: 282 SEEPIYIVTEYMNKGSLLDFLKDGEGRALKLP--NLVDMAAQVAAGMAYIERMNYIHRDL 339
E ++ +TEY+ G+L L E + +LP + + +A G+ Y+ +IHRDL
Sbjct: 345 HEGQLHALTEYIPSGNLEQLL---EKKDEELPWTQRIQLTLGLARGLDYLHSTRFIHRDL 515
Query: 340 RSANILV----GNGLICKIADFGLARLIE---DNEYTARQGAKFPIKWTAPEAALYGRF- 391
S NIL+ +G IADFGLA I D E G+ + W APE L G F
Sbjct: 516 TSKNILIRREDNHGYHAVIADFGLATKIPDPLDKEKLPTVGSPY---WMAPE-VLNGHFY 683
Query: 392 TIKSDVWSFGILLTELVTKGRVP-----YPGMNNREVLEQVERGYRMPCPQDCPISLHEL 446
++D++S GI++ E+ R+P P MNN V + V + CP+ +L
Sbjct: 684 NERADLFSVGIIMCEIT--ARIPADPDIMPRMNNFGV-DYVALSEMI---SYCPLDYLQL 845
Query: 447 MIHCWKKDPEERPTFEYLQSFLEDYF 472
C + DP++RP + +LE F
Sbjct: 846 AFKCCQVDPQKRPRGVEIIEWLEKIF 923
>17637
Length = 447
Score = 93.2 bits (230), Expect = 2e-19, Method: Compositional matrix adjust.
Identities = 46/132 (34%), Positives = 74/132 (56%), Gaps = 1/132 (0%)
Frame = +1
Query: 343 NILVGNGLICKIADFGLARLIEDNEYTARQGAKF-PIKWTAPEAALYGRFTIKSDVWSFG 401
N ++ + L K+ D L+R + +Y ++ PIKW + EA + SDVWSFG
Sbjct: 1 NCVIDDQLRVKLTDSALSRDLFSGDYNCLGDGEYRPIKWLSLEALQKSHYNEGSDVWSFG 180
Query: 402 ILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKKDPEERPTF 461
+L+ E+ T G++PY ++ E+ ++ GYR+ P +CP L +M +CW P ERP+F
Sbjct: 181 VLMWEMCTLGKLPYAEIDPYEMEHYLKDGYRLAQPFNCPDELFTIMAYCWASMPAERPSF 360
Query: 462 EYLQSFLEDYFT 473
LQ L ++ T
Sbjct: 361 SQLQICLSEFHT 396
>13592
Length = 980
Score = 90.5 bits (223), Expect = 1e-18, Method: Compositional matrix adjust.
Identities = 69/252 (27%), Positives = 130/252 (51%), Gaps = 17/252 (6%)
Frame = +2
Query: 224 KLGQGCFAEVWLGTWNGNTKV-AIK--TLKPG-TMSPESFLEEAQIMKKLKHDKLVQLYA 279
K+GQG F +V+ N ++ A+K ++PG T + ++ EE +I++ +KH LV+ Y
Sbjct: 5 KIGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETRALKNVAEELKILEGIKHKNLVRYYG 184
Query: 280 V-VSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVD--MAAQVAAGMAYIERMNYIH 336
+ V E + I E ++G+L ++ G LP + AQ+ +G+A + + +H
Sbjct: 185 IEVHREELLIFMELCSEGTLESLVELTGG----LPEALSRRFTAQLLSGVAELHKHGIVH 352
Query: 337 RDLRSANILVGNGL-ICKIADFGLARLIEDNE--------YTARQGAKFPIKWTAPEAAL 387
RD+++ANI + +G K+ DFG A I+ + Y Q P +T +
Sbjct: 353 RDIKTANIFLVDGSNSLKLGDFGSAVKIQAHTTVPGELQGYVGTQAYMAPEVFTKTNSDG 532
Query: 388 YGRFTIKSDVWSFGILLTELVTKGRVPYPGMN-NREVLEQVERGYRMPCPQDCPISLHEL 446
+GR +D+WS G ++ E+ + G+ P+ + N +++ +V G + P+ H+
Sbjct: 533 HGRL---ADIWSVGCVVVEMAS-GKRPWAQFDSNFQIMFKVGMGEKPQAPESLSQEGHDF 700
Query: 447 MIHCWKKDPEER 458
+ HC + DP++R
Sbjct: 701 IDHCLQHDPKQR 736
>14477
Length = 493
Score = 86.3 bits (212), Expect = 3e-17, Method: Compositional matrix adjust.
Identities = 55/160 (34%), Positives = 89/160 (55%), Gaps = 8/160 (5%)
Frame = -1
Query: 222 EKKLGQGCFAEVWLGTWNGNTK---VAIKTLKPGTMSPE---SFLEEAQIMKKLKHDKLV 275
E KLG G F V G + + VAIK LK + P ++EA++MKK+ H +V
Sbjct: 475 ELKLGAGNFGSVMKGVCRLDDREIPVAIKVLKNADLDPSVQSELIKEAEVMKKMDHMHIV 296
Query: 276 QLYAVVSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYI 335
+L + E + +V E G L FL + + L L N++++ QV+ GM Y+E ++
Sbjct: 295 RLIGLCEGETMMLVLELAKLGPLNKFLP--KNKHLPLWNILELMWQVSQGMEYLEANKFV 122
Query: 336 HRDLRSANILVGNGLICKIADFGLARLI--EDNEYTARQG 373
HRDL + NIL+ + KI+DFG+++ + E+N Y A++
Sbjct: 121 HRDLAARNILLCDEHFAKISDFGMSKTLSRENNYYMAQEA 2
>13305
Length = 549
Score = 79.7 bits (195), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 35/102 (34%), Positives = 59/102 (57%), Gaps = 4/102 (3%)
Frame = +2
Query: 373 GAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYR 432
+ PI+W A E+ +T +SDVWSFG++L E+ T G PY + +++ ++ GYR
Sbjct: 2 STRVPIRWMAVESLFNNTYTTQSDVWSFGVVLWEIFTLGGTPYSSTDTQQLFAFLKDGYR 181
Query: 433 MPCPQDCPISLHELMIHCWKKDPEERPTFE----YLQSFLED 470
+ P+ C + + +M+ CW ++ + RPTF LQ L+D
Sbjct: 182 LKRPKLCDQNTYAMMLQCWNENAQRRPTFPELCGRLQRMLDD 307
>19301
Length = 712
Score = 79.0 bits (193), Expect = 4e-15, Method: Compositional matrix adjust.
Identities = 50/153 (32%), Positives = 81/153 (52%), Gaps = 3/153 (1%)
Frame = +2
Query: 209 KDAWEVARRSLCLEKKLGQGCFAEVWLGTWNGNTKVAIKTLKPGTMSPESFLEEAQI--M 266
+D WE+ S+ + LG G V+LG +VA+K ++ ++E I +
Sbjct: 281 QDDWEIPFESITDLEWLGSGAQGAVFLGKLCAE-EVAVKKVRD--------IKETDIRNL 433
Query: 267 KKLKHDKLVQLYAVVSEEPIY-IVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAG 325
+KL H ++ V ++ P Y I+ EY G L + L+DG+ L ++D + Q+A+G
Sbjct: 434 RKLNHPNIISFKGVCTQAPCYCIIMEYCPYGQLYEVLRDGKEIPPAL--VLDWSKQIASG 607
Query: 326 MAYIERMNYIHRDLRSANILVGNGLICKIADFG 358
M Y+ IHRDL+S N+LV + KI+DFG
Sbjct: 608 MNYLHSHKIIHRDLKSPNVLVAKNDVVKISDFG 706
>01756
Length = 1858
Score = 77.0 bits (188), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 60/212 (28%), Positives = 94/212 (44%), Gaps = 22/212 (10%)
Frame = -3
Query: 224 KLGQGCFAEVWLGTWNGNTKVAIKTLKPGTMS------PESFLEEAQIMKKLKHDKLVQL 277
K+GQG F EV+ +V +K M P + L E +I++ L H+ +V L
Sbjct: 1721 KIGQGTFGEVFKARCKKTKQVV--AMKKVLMDNEKEGFPITALREIKILQLLNHENVVDL 1548
Query: 278 YAVVSEEP---------IYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAY 328
+ S + Y+V E+ L L LP + ++ Q+ G+ Y
Sbjct: 1547 IEICSTKATSANRYKSMFYLVFEFCEHD--LAGLLSNMSVVFNLPEIKEVMKQLMNGLYY 1374
Query: 329 IERMNYIHRDLRSANILVGNGLICKIADFGLAR-----LIEDNEYTARQGAKFPIKWTAP 383
I R +HRD+++ANIL+ + K+ADFGLAR L + N YT R W P
Sbjct: 1373 IHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNR----VVTLWYRP 1206
Query: 384 EAALYG--RFTIKSDVWSFGILLTELVTKGRV 413
L G ++ D W G ++ E+ T+ +
Sbjct: 1205 PELLLGDRNYSTAIDQWGAGCIMAEMWTRNPI 1110
>00715
Length = 1788
Score = 76.6 bits (187), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 62/223 (27%), Positives = 103/223 (46%), Gaps = 31/223 (13%)
Frame = +1
Query: 269 LKHDKLVQLYAVVS----EEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAA 324
L+H +V + S E+ ++ EY+ +L L D + + + + +A Q+A
Sbjct: 97 LRHVNVVSILGATSLHRFEDGAWLAMEYVGPLNLQTILNDHQ-QDIDSSMRLSLALQMAR 273
Query: 325 GMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLI----------------EDNEY 368
G+ Y+ +N +H DL+ AN L+ L +IADFG + + E
Sbjct: 274 GLHYLHSINIVHLDLKPANCLLTRDLKLRIADFGCCHQLTPTGLDMGEREGGMAGNELEL 453
Query: 369 TARQGA-----KFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREV 423
T QGA + + APE + +++SDV+S GI L ++ T+ + PY G+ V
Sbjct: 454 TPVQGAWKNELAGTLAYRAPELLKGLQPSVRSDVYSLGITLWQMCTR-QGPYEGVPAHAV 630
Query: 424 LEQVERGYRMPCP----QDCP--ISLHELMIHCWKKDPEERPT 460
+ QV PCP +D P + +L CW + E+RPT
Sbjct: 631 VYQVVSKDLRPCPPPSTEDDPFEVMFRDLYTQCWARRVEDRPT 759
>12721
Length = 821
Score = 71.6 bits (174), Expect = 7e-13, Method: Compositional matrix adjust.
Identities = 51/217 (23%), Positives = 100/217 (46%), Gaps = 3/217 (1%)
Frame = +1
Query: 224 KLGQGCFAEVWLGTWNGNTKVAIKTLKPGTMSPESFL-EEAQIMKKLKHDKLVQLYA--V 280
K+G+G V + T ++A+K + L E +M+ H +V++Y +
Sbjct: 109 KIGEGSTGIVCIATSRDGRQMAVKKMDLRKQQRRELLFNEVVVMRDYHHPNIVEMYNSYL 288
Query: 281 VSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLR 340
V++E +++V E+M G+L D + + +++ + + +A++ IHRD++
Sbjct: 289 VNDE-LWVVMEFMEGGALTDIVTNNRMDEVQIATVCRACLK---ALAFLHANGVIHRDIK 456
Query: 341 SANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSF 400
S +IL+ + K+ DFG + + + P W APE + + D+WS
Sbjct: 457 SDSILLSHDGKVKLXDFGFCAQVTQDLQKRKSLVGTPY-WMAPEVISRLPYGPEVDIWSL 633
Query: 401 GILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQ 437
GI++ E++ P N L+ + R MP P+
Sbjct: 634 GIMVMEMIDAE----PPFFNEPPLQAMRRIRDMPPPK 732
>17253
Length = 483
Score = 69.7 bits (169), Expect = 3e-12, Method: Composition-based stats.
Identities = 45/153 (29%), Positives = 69/153 (45%), Gaps = 16/153 (10%)
Frame = -1
Query: 244 VAIKTLKPGTMSPE--SFLEEAQIMKKL-KHDKLVQLYAVVS-EEPIYIVTEYMNKGSLL 299
VA+KT E FL E IM+KL +H +V + +P I+ E+ G LL
Sbjct: 459 VAVKTHNEAATDAEKSEFLRELSIMRKLPRHPNVVSFMGCCTMSDPALILMEFCCHGDLL 280
Query: 300 DFLKD----------GEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNG 349
FL+ L + A VA GMA++ +HRD+ + N+L+
Sbjct: 279 SFLRKRRPDRTVFLTSTANDLTARDFFSFALHVARGMAHVANNKIVHRDVAARNVLISER 100
Query: 350 LICKIADFGLARLIEDNE--YTARQGAKFPIKW 380
+CK++DFGL+R + D Y P++W
Sbjct: 99 NVCKVSDFGLSRRVGDQNDVYEIVSRRPLPLRW 1
>01060
Length = 1800
Score = 69.7 bits (169), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 62/255 (24%), Positives = 117/255 (45%), Gaps = 13/255 (5%)
Frame = +1
Query: 212 WEVARRSLCLEKKLGQGCFAEVW------LGTWNGNTKVAIKTLKPGTMSPESFLEEAQI 265
+E A L +K+G+G + V+ G K+ ++ + G P S + E +
Sbjct: 58 FETALSDLTDFQKIGEGTYGVVYKCRHRATGRKLAMKKIRLRGSEDGV--PSSAIREIAM 231
Query: 266 MKKLKHDKLVQLYAVVSE-EPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAA 324
+++L+H +V L V+ E E +++V E+++ + K EG L + Q+
Sbjct: 232 LRELRHTNIVCLEDVIMEDERLFLVFEFLSMDLKMYIDKFPEGVVLDRRLVKSYVFQIVT 411
Query: 325 GMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPE 384
G+ + + +HRDL+ N+L+ + KIADFG+AR A + + APE
Sbjct: 412 GIXFCHQRRIVHRDLKPQNLLINHTGAIKIADFGMARTFA-LPVRAYTHEVVTLWYRAPE 588
Query: 385 AAL-YGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPISL 443
+ +++ DVWS G + +++ + + + G + + L ++ R P Q P
Sbjct: 589 ILMGASKYSTPVDVWSIGTIFADMLIRTPI-FKGDSEIDQLFKIFRIIGTPTEQTWP-EF 762
Query: 444 HEL-----MIHCWKK 453
H+L M WK+
Sbjct: 763 HKLPAFNGMFPLWKE 807
>01707
Length = 757
Score = 68.2 bits (165), Expect = 7e-12, Method: Compositional matrix adjust.
Identities = 63/216 (29%), Positives = 110/216 (50%), Gaps = 10/216 (4%)
Frame = +1
Query: 224 KLGQGCFAEVWLGTWNGNTK--VAIKTLKPGTMSP---ESFLEEAQIMKKLKHDKLVQLY 278
K+G+G + V+ N T VAIK P + + E +++K+LKH LV+L
Sbjct: 85 KIGEGSYGVVF-KCRNKETSQLVAIKKFVESEDDPLIKKIAMREIRMLKQLKHPNLVRLI 261
Query: 279 AVVSEEP-IYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHR 337
V + +++V +Y++ +LL+ L D R L P + + Q + + + N IHR
Sbjct: 262 EVFRRKKRLHLVFDYVDH-TLLNEL-DRYPRGLPEPMVKRIIYQTLLAVNFCHQYNTIHR 435
Query: 338 DLRSANILVGNGLICKIADFGLARLIE--DNEYTARQGAKFPIKWTAPEAALYG--RFTI 393
D++ NIL+ K+ DFG AR++ +EYT ++ + APE L G ++
Sbjct: 436 DVKPENILITRQGQVKLCDFGFARILTGPGDEYTDYVATRW---YRAPE-LLVGDTQYGP 603
Query: 394 KSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVER 429
DVW+ G + EL+T G+ +PG ++ + L + +
Sbjct: 604 PVDVWAIGCVFAELLT-GQALWPGRSDVDQLHLIRK 708
>18921
Length = 697
Score = 67.4 bits (163), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 53/193 (27%), Positives = 89/193 (46%), Gaps = 2/193 (1%)
Frame = +2
Query: 224 KLGQGCFAEVWLGTWNGNTKV-AIKTLKPGTMSPESFLEEAQIMKKLKHDKLVQLY-AVV 281
KLG+G + V+ +V AIK + P + ++E IM++ +V+ Y +
Sbjct: 50 KLGEGSYGSVFKSLHKETGQVLAIKQV-PVDTDLQEIIKEISIMQQCDSKYIVKYYGSYF 226
Query: 282 SEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRS 341
++IV EY GS+ D ++ + L + + G+ Y+ IHRD+++
Sbjct: 227 KNTDLWIVMEYCGAGSVSDIMR-LRNKTLVEREIATILYYTLKGLXYLHSRRKIHRDIKA 403
Query: 342 ANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFG 401
NIL+ N K+ADFG+A + D P W APE + +D+WS G
Sbjct: 404 GNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTPY-WMAPEVIQEIGYDCVADIWSLG 580
Query: 402 ILLTELVTKGRVP 414
I E+ +G+ P
Sbjct: 581 ITALEM-AEGKPP 616
>29581
Length = 1278
Score = 65.9 bits (159), Expect = 4e-11, Method: Compositional matrix adjust.
Identities = 59/191 (30%), Positives = 91/191 (47%), Gaps = 11/191 (5%)
Frame = -2
Query: 249 LKPGTMSPESFLEEAQIMKKLKHDKLVQLYAVV---SEEPIYIVTEYMNK--GSLLDFLK 303
L+ +SP + + L+H +VQL VV S + +++V EY + SLLD +
Sbjct: 1244 LERDMVSPSVVCVRSTFLLNLRHQNIVQLQEVVVGKSLDSLFLVMEYCEQDLASLLDNMP 1065
Query: 304 DGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLI 363
+ + + Q+ G+ Y+ IHRDL+ +N+L+ + KIADFGLAR
Sbjct: 1064 APFSES----QVKCIVLQLLKGLRYLHEAFIIHRDLKVSNLLMTDKGCVKIADFGLAR-- 903
Query: 364 EDNEYTARQGAKFP----IKWTAPEAALYGRFTIKS--DVWSFGILLTELVTKGRVPYPG 417
Y Q P + + APE L+G T + D+WS G +L EL+ P
Sbjct: 902 ---NYGKPQKPMTPKVVTLWYRAPE-LLFGSKTHSTAIDMWSAGCILGELLGHK----PL 747
Query: 418 MNNREVLEQVE 428
M R L+Q+E
Sbjct: 746 MPGRSDLQQIE 714
>14126
Length = 1265
Score = 64.7 bits (156), Expect = 9e-11, Method: Compositional matrix adjust.
Identities = 64/272 (23%), Positives = 124/272 (45%), Gaps = 23/272 (8%)
Frame = +3
Query: 196 IASSCTPQ-TSGLAKDAWEVARRSLCLEKK------LGQGCFAEVWLG--TWNGNTKVAI 246
+ ++ +P+ G ++ A +++RR E+K +G G + V+ N VA+
Sbjct: 105 MKTAISPKGRDGQSESAAKMSRRRDSTEQKYEEVAVIGNGAYGTVYKARDLRNQGEFVAM 284
Query: 247 KTLKPGTMS---PESFLEEAQIMKKLK---HDKLVQLYAVV------SEEPIYIVTEYMN 294
K ++ P + E ++K+L+ H +V+L V E + +V EY+
Sbjct: 285 KRIRLNNTEEGMPMMAIREISMLKQLEQYEHPNVVRLLDVSHNTITDREIRLNLVFEYI- 461
Query: 295 KGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKI 354
+ L +L L + D+ Q+ G+ ++ +HRDL+ N+L+ K+
Sbjct: 462 EHDLATYLAKCPSPGLGPDRIKDLMLQLLNGVDFLHSNRIVHRDLKPQNLLISKDGRLKL 641
Query: 355 ADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVP 414
ADFGLAR+ + + A + + +PE + + D+WS G + EL T+ R
Sbjct: 642 ADFGLARIY--SFHMALTTVVVTLWYRSPEVLMQAEYGTSVDIWSCGCIFAELFTR-RAL 812
Query: 415 YPGMNNREVLEQVERGYRMPCPQDCP--ISLH 444
+ G + + L+++ +P D P +S+H
Sbjct: 813 FKGSSEFDQLKKIFEVIGLPPAGDWPEGVSVH 908
>00300
Length = 2318
Score = 63.9 bits (154), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 57/251 (22%), Positives = 118/251 (47%), Gaps = 16/251 (6%)
Frame = -1
Query: 224 KLGQGCFAEVWLGT-WNGNTKVAIKTLK--PGTMSP-ESFLEEAQIMKKLKHDKLVQLYA 279
K+G+G F +V+ + +A+K +K P + +E +I + ++H+ LV+ Y
Sbjct: 1637 KIGEGQFGKVYTAVNMSTGELMALKEMKFQPNDLQQLREMCDEIKIFEGIQHENLVKYYG 1458
Query: 280 V-VSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPN--LVDMAAQVAAGMAYIERMNYIH 336
V V ++ + + EY + G++ + K G LP + ++ + ++ + +H
Sbjct: 1457 VEVHKDEMLMFMEYCDTGTIEEAAKMG------LPEYLIRRYTREIVLAVNHLHENSIVH 1296
Query: 337 RDLRSANILVGNGLICKIADFGLARLIEDN-----EYTARQGAK---FPIKWTAPEAALY 388
RD++ ANI + + K+ DFG + ++ + E+ G P +T + Y
Sbjct: 1295 RDIKGANIFLTSNGHVKLGDFGCSVKLKSHTTMPGEFHNLVGTTAYMAPEVFTQNDQGGY 1116
Query: 389 GRFTIKSDVWSFGILLTELVTKGRVPYPGM-NNREVLEQVERGYRMPCPQDCPISLHELM 447
GR +D+WS G ++ E+ T G+ P+ + NN +++ +V G++ P + +
Sbjct: 1115 GR---AADIWSLGCVVIEMAT-GKRPWHDLDNNYQIMYKVGIGHKPAVPDSLSVEGKHFL 948
Query: 448 IHCWKKDPEER 458
DP +R
Sbjct: 947 DLIMCHDPAQR 915
>25550
Length = 941
Score = 63.5 bits (153), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 29/63 (46%), Positives = 41/63 (65%)
Frame = +3
Query: 413 VPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKKDPEERPTFEYLQSFLEDYF 472
V YPG++ EV +ERGYRM PQ P ++ LM+ CW+ DP+ERPTF+ + LE+ F
Sbjct: 36 VXYPGVDLTEVYHLLERGYRMERPQGTPADVYILMLKCWQWDPKERPTFKEIHYLLENMF 215
Query: 473 TAT 475
+
Sbjct: 216 EKS 224
>18484
Length = 635
Score = 63.2 bits (152), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 37/122 (30%), Positives = 65/122 (53%)
Frame = +1
Query: 306 EGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIED 365
EG+ K P AA++A G+ ++ I+RDL+ N+++ + KIADFG+ +
Sbjct: 25 EGK-FKEPVAAFYAAEIAVGLFFLHDQGIIYRDLKLDNVMLDSEGHIKIADFGMCKEGMT 201
Query: 366 NEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLE 425
+ T R P + APE LY ++ D W++G+LL E++ G+ P+ G + E+
Sbjct: 202 GDATTRTFCGTP-DYIAPEIVLYQPYSKSVDWWAYGVLLFEMLA-GQPPFDGEDEDELFS 375
Query: 426 QV 427
+
Sbjct: 376 SI 381
>14420
Length = 528
Score = 62.0 bits (149), Expect = 6e-10, Method: Compositional matrix adjust.
Identities = 40/166 (24%), Positives = 80/166 (48%), Gaps = 3/166 (1%)
Frame = +2
Query: 257 ESFLEEAQIMKKLKHDKLVQ-LYAVVSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNL 315
E + E +M++ ++ +V L + + E +++V E++ GSL D + + + +
Sbjct: 35 ELIINEILVMRENQNPNIVNYLDSYLVGEELWVVMEFLAGGSLTDVVTE---TCMDEGQI 205
Query: 316 VDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLI--EDNEYTARQG 373
+ + + ++ IHRD++S NIL+G K+ DFG + E ++ + G
Sbjct: 206 AAVCRECLQALEFLHENQVIHRDIKSDNILLGMDGSVKLTDFGFCAQLSPEQSKRSTMVG 385
Query: 374 AKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMN 419
+ W APE ++ D+WS G++ E++ +G PY N
Sbjct: 386 TPY---WMAPEVVTRKQYGPTVDIWSLGVMCIEMI-EGEPPYLNEN 511
>27546
Length = 426
Score = 61.2 bits (147), Expect = 1e-09, Method: Composition-based stats.
Identities = 36/114 (31%), Positives = 56/114 (49%), Gaps = 7/114 (6%)
Frame = -1
Query: 259 FLEEAQIMKKLKHDKLVQLYAVVSEEP-IYIVTEYMNKGSLLDFLKDGEGRALKLPNLVD 317
F E +I+ +L H ++Q+++++ P I+I Y KG +L +K +D
Sbjct: 339 FPRELEILTRLDHPNIIQIHSILQRGPKIFIFMRYAEKGDMLSHIKK--------TGPID 184
Query: 318 MAA------QVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIED 365
A Q+A + Y+ + HRDL+ NIL+ L KIADFG AR D
Sbjct: 183 EAQTKVWFFQMAKALQYLHSHDIAHRDLKCENILLSKRLNVKIADFGFARYCRD 22
>04591
Length = 1117
Score = 60.5 bits (145), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 44/169 (26%), Positives = 83/169 (49%), Gaps = 14/169 (8%)
Frame = -2
Query: 256 PESFLEEAQIMKKLKHDKLVQLYAVVSEEP---------IYIVTEYMN--KGSLLDFLKD 304
P + L E +I+++L+H+ +VQL + + Y++ EY + LL+ L+
Sbjct: 1089 PITALREIKILQQLEHENVVQLQEICHTQAGPYNRYKSTFYLIFEYCDYDLAGLLNNLR- 913
Query: 305 GEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLAR-LI 363
L + ++ +Q+ G+ YI +HRD+++ANIL+ + K+ADFGL+R +
Sbjct: 912 ---VKFSLADKKNLMSQLLNGLFYIHTKQILHRDIKAANILLTRDGVLKLADFGLSRPWV 742
Query: 364 EDNEYTARQGAKFPIKWTAPEAALYG--RFTIKSDVWSFGILLTELVTK 410
+ T R W P L G + + D+W G ++ E+ ++
Sbjct: 741 KSKRLTNR----VVTLWYRPPELLLGEREYGPEIDMWGVGCIMAEMWSR 607
>00392
Length = 668
Score = 58.5 bits (140), Expect = 6e-09, Method: Compositional matrix adjust.
Identities = 53/174 (30%), Positives = 88/174 (50%), Gaps = 10/174 (5%)
Frame = +3
Query: 257 ESFLEEAQIMKKLKHDKLVQLYAVVSE------EPIYIVTEYMNKGSLLDFLKDGEGRAL 310
+ F EEA+++K+L+H +V+ + E + I +VTE M G+L +LK + +
Sbjct: 66 QRFKEEAEMLKELQHPNIVRFFDYWEEHNHRNRKVIILVTELMTSGTLKTYLKRFKKPNV 245
Query: 311 KLPNLVDMAAQVAAGMAYIERMN--YIHRDLRSANILV-GNGLICKIADFGLARLIEDNE 367
K+ L + QV G+ ++ IHRDL+ NI + G KI D GLA L N+
Sbjct: 246 KI--LKNWCRQVLKGLYFLHTRTPPVIHRDLKCDNIFITGPTGSVKIGDLGLATL--KNQ 413
Query: 368 YTARQGAKFPIKWTAPEAALY-GRFTIKSDVWSFGILLTELVTKGRVPYPGMNN 420
A+ P ++ APE +Y + DV++FG+ + E+ + PY +N
Sbjct: 414 SFAKSVIGTP-EFMAPE--MYEEHYDEAVDVYAFGMCMLEMAS-SEYPYSECSN 563
>01966
Length = 1735
Score = 58.2 bits (139), Expect = 7e-09, Method: Compositional matrix adjust.
Identities = 32/107 (29%), Positives = 58/107 (54%), Gaps = 1/107 (0%)
Frame = -1
Query: 256 PESFLEEAQIMKKLKHDKLVQLYAVVSE-EPIYIVTEYMNKGSLLDFLKDGEGRALKLPN 314
P S + E ++++L+H +V L V+ E E +++V E+++ + K EG L
Sbjct: 1582 PSSAIREIAMLRELRHTNIVCLEDVIMEDERLFLVFEFLSMDLKMYIDKFPEGVVLDRRL 1403
Query: 315 LVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLAR 361
+ Q+ G+ + + +HRDL+ N+L+ + KIADFG+AR
Sbjct: 1402 VKSYVFQIVTGINFCHQRRIVHRDLKPQNLLINHTGAIKIADFGMAR 1262
>31885
Length = 529
Score = 57.0 bits (136), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 46/169 (27%), Positives = 78/169 (46%), Gaps = 6/169 (3%)
Frame = -2
Query: 263 AQIMKKLKHDKLVQL-YAVVSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQ 321
++ +L H LV L YA EE +++V + G L ++ + + + + Q
Sbjct: 519 VDMLTRLDHPFLVNLWYAFQDEEDLFMVVDLFLGGDLRYHMQ--QEVSFREDCVKFYLCQ 346
Query: 322 VAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWT 381
+A + Y+ +HRD++ NIL+ C + DF +A +ED+E P +
Sbjct: 345 LALVLDYLRSQKIVHRDIKPDNILLDEQGHCHVTDFNIATQLEDDELATSTSGTRP--YM 172
Query: 382 APE---AALYGR--FTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLE 425
APE A+ R + D WS G+ L EL+ K R P+ +N + E
Sbjct: 171 APEVYGVAINERRGYGFPVDWWSLGVSLFELLKKRR-PFSVHSNTSLHE 28
>13066
Length = 551
Score = 56.6 bits (135), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 48/183 (26%), Positives = 81/183 (44%), Gaps = 12/183 (6%)
Frame = +3
Query: 231 AEVWLGTWNG----NTKVAIKTL----KPGTMSPESFLEEAQIMKKLKHDKLVQLYAVVS 282
A V GT+N N K+A K + P + F E ++ KL H ++Q+++++
Sbjct: 9 AVVVHGTFNDGYGRNIKLACKIIDKEKAPVDFVEKFFPRELDLLTKLDHPYIIQIHSILQ 188
Query: 283 EEPI-YIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRS 341
P +I + +G LL +++ E +K Q+ + Y+ + HRDL+
Sbjct: 189 RXPKNFIFMRFAERGDLLTYIQ--EVGFVKEKQAKIWFYQMTTALNYLHSYDVAHRDLKC 362
Query: 342 ANILVGNGLICKIADFGL--ARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIK-SDVW 398
NIL+ + K+ADFG A + E E + + APE + K +D W
Sbjct: 363 ENILLSSHFNVKLADFGFACACITESGEKYMSRTYCGSAAYAAPEIVYGAPYAPKVADAW 542
Query: 399 SFG 401
S G
Sbjct: 543 SLG 551
>07836
Length = 1478
Score = 56.6 bits (135), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 62/217 (28%), Positives = 100/217 (46%), Gaps = 42/217 (19%)
Frame = -1
Query: 286 IYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIE--------RMNYIHR 337
++++T+Y GSL D+L R L ++ +A G+A++ + HR
Sbjct: 1328 LFLITDYHENGSLHDYLL---SRVLDSSEMLALAHSAICGLAHLHIEIFGTRGKPAIAHR 1158
Query: 338 DLRSANILVGNGLICKIADFGLA-RLI-EDNEYTA----RQGAKFPIKWTAPEAALYGRF 391
D++S NILV C IAD GLA R I E NE RQG K ++ APE L
Sbjct: 1157 DIKSKNILVKKNGTCCIADLGLAVRYISESNEVDVAPNPRQGTK---RYMAPE-VLEMLL 990
Query: 392 TIK-------SDVWSFGILLTEL----VTKG-----RVPY-------PGMNNREVLEQVE 428
+K +D+++FG+++ E+ V G +VP+ P + ++ V+
Sbjct: 989 NVKNFDAFKQADMYAFGLVMWEIARCCVIGGVAEEYQVPFYNCLPHDPSFEDVRLVVSVD 810
Query: 429 RGYRMPCP---QDCPI--SLHELMIHCWKKDPEERPT 460
+ R P Q+ PI + ++M CW +P R T
Sbjct: 809 K-VRPDIPLRWQEDPIMKVMVKVMCECWSGNPAARLT 702
>09606
Length = 1300
Score = 55.1 bits (131), Expect = 7e-08, Method: Compositional matrix adjust.
Identities = 52/224 (23%), Positives = 96/224 (42%), Gaps = 23/224 (10%)
Frame = -3
Query: 217 RSLCLEKKLGQGCFAEVWLGTWNGNTK-VAIKTLKPGTMSPESFLEEAQIMKKLKHDKLV 275
+ L ++LG+G + ++ G G VAI ++ PE ++ + H +V
Sbjct: 1115 ENFVLYEELGKGEHSIIYKGRRKGTINFVAIHCIEK-CKRPE-VTNTVRMTHDISHPNVV 942
Query: 276 QLYA-VVSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNY 334
Q + + +++V E GSL D L + L ++ D + G+ YI +
Sbjct: 941 QFHEWYETSNHLWLVVELCTGGSLADIL--AQDHHLPETSIRDFGIHLVTGLHYIHSLGI 768
Query: 335 IHRDLRSANILVGNGLICKIADFGLARLIEDNEYT-----ARQGAKFPIK---------- 379
+ DLR + +L+ + K ADFGL+++ +N A G ++ I+
Sbjct: 767 LFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQWNIQSAEEMMKQVP 588
Query: 380 ------WTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPG 417
+ APE +I SD+W+ G + E+ + G P+ G
Sbjct: 587 TSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFS-GHPPFLG 459
>03240
Length = 1683
Score = 54.7 bits (130), Expect = 8e-08, Method: Compositional matrix adjust.
Identities = 46/161 (28%), Positives = 75/161 (46%), Gaps = 9/161 (5%)
Frame = -3
Query: 223 KKLGQGCFAEVWLGTWNGNTKV-AIKTLKPGTMSPESFLE----EAQIMKKLKHDKLVQL 277
K LG G F EV L N + A+KTL+ + + + E I+ + ++ +V+L
Sbjct: 1273 KTLGVGAFGEVSLCRKNDTGMLYAMKTLRKSDVLKRNQVAHVKAERDILAEADNEWVVKL 1094
Query: 278 YAVVSEEP-IYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIH 336
Y + +Y V +Y+ G L+ L E L P A++ + + RM +IH
Sbjct: 1093 YYSFQDHNYLYFVMDYVPGGDLMGLLIRME--ILDEPLARFYVAELVQAIESVHRMGFIH 920
Query: 337 RDLRSANILVGNGLICKIADFGLA---RLIEDNEYTARQGA 374
RD++ NIL+ K+ DFGL R +++Y R G
Sbjct: 919 RDIKPDNILIDRNGHIKLTDFGLCTGFRWTHNSKYYQRDGT 797
>12672
Length = 773
Score = 53.9 bits (128), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 40/164 (24%), Positives = 74/164 (45%), Gaps = 16/164 (9%)
Frame = +3
Query: 323 AAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPI---K 379
A+G+ Y+ ++HRD+++ANIL+ + K+ DF E Q A I
Sbjct: 21 ASGIQYLNDNGHVHRDIKTANILLDSEYTAKVGDFATVVSAPSGEGKTVQNASVVIGTAA 200
Query: 380 WTAPEAALYGRFTIKSDVWSFGILLTELVT----------KGRVPYPGMNNREVLEQVER 429
+ APE A++ + K D +SFG++L E++T + + M N E E++
Sbjct: 201 YLAPE-AIHFDVSTKLDSYSFGVVLLEVITGLVAQDYSREERTLSSHIMENVEEPEEIHD 377
Query: 430 GYRMPC---PQDCPISLHELMIHCWKKDPEERPTFEYLQSFLED 470
P L+++ + C ++RP + ++ LE+
Sbjct: 378 FVDQSAGTWPDGAVDKLYDISMRCLNLSKKQRPNVKDIRPELEE 509
>13212
Length = 1067
Score = 52.8 bits (125), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 45/167 (26%), Positives = 76/167 (45%), Gaps = 11/167 (6%)
Frame = -1
Query: 321 QVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKF---P 377
++ + ++ R + IHRD+++ N+L+ K+ADFG++ N T ++ F P
Sbjct: 956 EMCMALDFLHRHHVIHRDIKAGNVLLTIDGEVKLADFGVSA---KNTQTQQKRDTFIGTP 786
Query: 378 IKWTAPEAALY-----GRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERG-- 430
W APE L + K+D+WS G+ L E + P M+ VL ++ +
Sbjct: 785 Y-WMAPEVVLCETLKDTPYDFKADIWSLGVTLIEFA-QIEPPNKEMHPMRVLIKIHKSDP 612
Query: 431 YRMPCPQDCPISLHELMIHCWKKDPEERPT-FEYLQSFLEDYFTATE 476
+ P+ + + C KDP RPT E L+ TAT+
Sbjct: 611 PTLEKPKKWTKLFKDFIAKCLVKDPNLRPTAAELLEHPFMKRATATD 471
>04138
Length = 800
Score = 52.4 bits (124), Expect = 4e-07, Method: Compositional matrix adjust.
Identities = 32/93 (34%), Positives = 47/93 (50%), Gaps = 7/93 (7%)
Frame = +1
Query: 328 YIERMNYIHRDLRSANILVGNGLICKIADFGLAR-----LIEDNEYTARQGAKFPIKWTA 382
YI R +HRD+++ANIL+ + K+ADFGLAR L + N YT R W
Sbjct: 58 YIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNR----VVTLWYR 225
Query: 383 PEAALYG--RFTIKSDVWSFGILLTELVTKGRV 413
P L G ++ D W G ++ E+ T+ +
Sbjct: 226 PPELLLGDRNYSTAIDQWGAGCIMAEMWTRNPI 324
>21079
Length = 878
Score = 51.6 bits (122), Expect = 7e-07, Method: Compositional matrix adjust.
Identities = 39/143 (27%), Positives = 69/143 (48%), Gaps = 4/143 (2%)
Frame = +1
Query: 271 HDKLVQLY-AVVSEEPIYIVTEYMNKGSLLD-FLKDGEGRALKLPNLVDMAAQVAAGMAY 328
H KL+ L+ A + + +V E++ G L + ++D L + V Q+ +G+ Y
Sbjct: 1 HPKLLMLWDAFEAPRTMVLVMEFVGAGELFERVIRDD--FVLTERDCVHFVRQICSGVGY 174
Query: 329 IERMNYIHRDLRSANILV--GNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAA 386
+ + +H DL+ N+L N KI DFGLAR + + + Q ++ APE
Sbjct: 175 MHTQSILHLDLKPENVLCVSDNSNQIKIIDFGLARFYKPGD--SLQVLFGTPEFIAPEVV 348
Query: 387 LYGRFTIKSDVWSFGILLTELVT 409
Y +D+WS G++ L++
Sbjct: 349 NYDEINFTTDMWSIGVICYILLS 417
>19094
Length = 898
Score = 48.5 bits (114), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 28/83 (33%), Positives = 41/83 (49%)
Frame = +1
Query: 325 GMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPE 384
G+ Y+ IHRD+++ NIL+ N K+ADFG+A + D P W APE
Sbjct: 94 GL*YLHSRRKIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTP-YWMAPE 270
Query: 385 AALYGRFTIKSDVWSFGILLTEL 407
+ +D+WS GI E+
Sbjct: 271 VIQEIGYDCVADIWSLGITALEM 339
>29243
Length = 1147
Score = 48.5 bits (114), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 32/95 (33%), Positives = 48/95 (50%), Gaps = 4/95 (4%)
Frame = +2
Query: 99 EWYFGKLGRKDAERQLLSFGNPRGTFLIRESETT--KGAYSLSIRDWDDMKGDHVKHYKI 156
WY G + R A++ L + P GTFLIR + +G SLSI+ + V+H K+
Sbjct: 305 NWYVGIMERPVAQKXLDTC--PDGTFLIRVTNNPLRRGELSLSIK-----YANAVRHIKV 463
Query: 157 RKLDNGGYYITTRAQFETLQQLVQHY--SEKADGL 189
+ G +Y+ F+ +Q LV HY +E AD
Sbjct: 464 NRNPQGRFYLADGRYFDNIQSLVDHYENNELADSF 568
>15910
Length = 1361
Score = 47.8 bits (112), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 34/114 (29%), Positives = 57/114 (50%), Gaps = 3/114 (2%)
Frame = +2
Query: 320 AQVAAGMAYIERMNYIHRDLRSANIL---VGNGLICKIADFGLARLIEDNEYTARQGAKF 376
+ + G+ YI +HRDL+ N+L + + K+ADFGL+R+IE E
Sbjct: 485 SDILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLADFGLSRIIEP-EVQMSTVCGT 661
Query: 377 PIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERG 430
P + APE ++T D+WS G++ L+ G P+ N E+ ++ +G
Sbjct: 662 P-GYCAPEVLKGDKYTPSVDMWSVGVIAYILLC-GYEPFFAENEFEMYRKIIKG 817
>30755
Length = 1137
Score = 47.4 bits (111), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 37/142 (26%), Positives = 66/142 (46%), Gaps = 2/142 (1%)
Frame = +2
Query: 319 AAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEY--TARQGAKF 376
A++ + + Y+ I+RDL+ N+L+ K+ADFGL + ED Y T +
Sbjct: 50 GAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCK--EDITYGRTTKTFCGT 223
Query: 377 PIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCP 436
P ++ APE + D W G+++ E++ GR+P+ + +VL + + P
Sbjct: 224 P-EYLAPEVLDDNDYGRAVDWWGTGVVMYEMIC-GRLPFYN-RDHDVLFTLILVEDVKFP 394
Query: 437 QDCPISLHELMIHCWKKDPEER 458
++ L+ KDP R
Sbjct: 395 RNITDEAKSLLSGLLAKDPRNR 460
>26560
Length = 398
Score = 46.2 bits (108), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 32/103 (31%), Positives = 52/103 (50%), Gaps = 1/103 (0%)
Frame = -1
Query: 319 AAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPI 378
AA+V G+ ++ ++RDL+ ANIL+ +I+D GLA A G
Sbjct: 338 AAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGLACDFSKKRPHASVGTH--- 168
Query: 379 KWTAPEAALYGR-FTIKSDVWSFGILLTELVTKGRVPYPGMNN 420
+ APE + G+ + +D +SFG +L +L+ KG P+ N
Sbjct: 167 GYMAPEVLMKGQSYDSSADWFSFGCMLYKLL-KGHSPFRQHNQ 42
>21210
Length = 518
Score = 45.8 bits (107), Expect = 4e-05, Method: Compositional matrix adjust.
Identities = 34/86 (39%), Positives = 47/86 (54%), Gaps = 4/86 (4%)
Frame = +3
Query: 383 PEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPG-MNNREVLEQVERGYRMPC-PQDCP 440
P A+ +G + ++SDVWS GI L EL T GR PY ++ + L+QV RG PC P D
Sbjct: 42 PRASSHG-YDVRSDVWSLGITLMELAT-GRFPYRKWVSIFDQLQQVVRGV-APCLPHDGA 212
Query: 441 IS--LHELMIHCWKKDPEERPTFEYL 464
S + C KD ++RP + L
Sbjct: 213 FSHDFVNFVNKCLTKDEKQRPKYNKL 290
>19761
Length = 473
Score = 45.1 bits (105), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 34/119 (28%), Positives = 54/119 (45%), Gaps = 3/119 (2%)
Frame = -3
Query: 321 QVAAGMAYIERMN--YIHRDLRSANILVGNGLICKIADFGLAR-LIEDNEYTARQGAKFP 377
Q A+ + Y+ +HRDL+ NI V ++ D GLAR L ++ Q
Sbjct: 399 QTASALNYMHTHTPVILHRDLKPQNIYVTEKGDVRLGDLGLARKLTGPADFATSQVGT-- 226
Query: 378 IKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCP 436
I + +PE + KSD+WS G + ++ G+ M +L QV G ++P P
Sbjct: 225 IMYLSPEILSQQPYNSKSDIWSLGCVFYDIT--GKKGSDEMGVMFLLVQVMGGRKLPLP 55
>11185
Length = 473
Score = 44.7 bits (104), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 35/142 (24%), Positives = 61/142 (42%), Gaps = 25/142 (17%)
Frame = +1
Query: 317 DMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYT-----AR 371
D + G+ YI + + DLR + +L+ + K ADFGL+++ +N A
Sbjct: 13 DFGIHLVTGLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAE 192
Query: 372 QGAKFPIK----------------WTAPEAALYGRFTIKSDVWSFGILLTELVTKGRV-- 413
G ++ I+ + APE +I SD+W+ G + E+ + R+
Sbjct: 193 AGDQWNIQSAEEMMKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSGSRLSA 372
Query: 414 -PYPG-MNNREVLEQVERGYRM 433
P P +N E L Q + R+
Sbjct: 373 KPSPEFLNLLESLLQKDSTRRL 438
>14257
Length = 919
Score = 44.3 bits (103), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 28/89 (31%), Positives = 47/89 (52%)
Frame = -3
Query: 98 EEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDWDDMKGDHVKHYKIR 157
EEWY GK+GRK+AE+ L G FL+RE+ + + LS R + +V+H +
Sbjct: 896 EEWYHGKIGRKEAEKLL----ELDGDFLVREASNSAAQFVLSGR-----QNGNVRHLLL- 747
Query: 158 KLDNGGYYITTRAQFETLQQLVQHYSEKA 186
+D G T F+++ L+ ++ + A
Sbjct: 746 -VDPDGIVRTKDFIFDSVSHLINYHRQNA 663
>01106
Length = 878
Score = 43.1 bits (100), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 38/140 (27%), Positives = 69/140 (49%), Gaps = 16/140 (11%)
Frame = +3
Query: 223 KKLGQGCFAEVWLGTWNGNTK--VAIKTLKPGTMSPESFLEEAQIMKKLKHD-------- 272
+KLG G F+ VWL W+ K VA+K +K E+ L+E +++K ++
Sbjct: 336 RKLGWGHFSTVWL-CWDLTCKRFVALKVVKSAQHYTETALDEVKLLKCVRESDVADPARA 512
Query: 273 KLVQLY-----AVVSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMA 327
K VQL + V+ + +V E + +LL + + + + N+ + QV G++
Sbjct: 513 KCVQLLDDFKISGVNGTHVAMVFEVLGY-NLLKLIIRSNYQGIPIHNVKLIIRQVLEGLS 689
Query: 328 YIE-RMNYIHRDLRSANILV 346
Y+ + IH D++ NIL+
Sbjct: 690 YMHAKCRIIHTDIKPENILI 749
>28638
Length = 1458
Score = 42.0 bits (97), Expect = 5e-04, Method: Compositional matrix adjust.
Identities = 34/108 (31%), Positives = 52/108 (48%), Gaps = 4/108 (3%)
Frame = -1
Query: 306 EGRALKLPNLVDMAAQVAAGMAYIE--RMNYIHRDLRSANILVGNG--LICKIADFGLAR 361
EG +L L A Q+ + ++ MN IH DL+ NIL+ N KI DFG +
Sbjct: 852 EGVSLNLTR--KFAQQLCTALLFLATPEMNIIHCDLKPENILLCNPKRSAIKIVDFGSSC 679
Query: 362 LIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVT 409
+ Y Q ++F + +PE L + + D+WS G +L E+ T
Sbjct: 678 QLGQRIYQYIQ-SRF---YRSPEVLLGVPYDLAIDMWSLGCILVEMHT 547
>26711
Length = 405
Score = 41.6 bits (96), Expect = 8e-04, Method: Composition-based stats.
Identities = 31/111 (27%), Positives = 54/111 (48%), Gaps = 3/111 (2%)
Frame = -2
Query: 321 QVAAGMAYIERMNYIHRDLRSANILVGNGLI--CKIADFGLAR-LIEDNEYTARQGAKFP 377
QV + ++ +H DL+ +N+L+ + ++ DFGLAR L E G
Sbjct: 392 QVLDILQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARKLYPPQETFLNHGTP-- 219
Query: 378 IKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVE 428
+T+PEA + SDVW G+L L++ G+ P+ + E L++ +
Sbjct: 218 -GFTSPEALDVKPISTASDVWGVGVLAYILLS-GQSPFQADSATESLKKTQ 72
>12786
Length = 460
Score = 41.2 bits (95), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 27/107 (25%), Positives = 51/107 (47%), Gaps = 21/107 (19%)
Frame = -3
Query: 335 IHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPI-KWTAPEAALYG---- 389
IH DL+ AN ++ G + K+ DFG+A ++ ++ + + ++ + +PEA +
Sbjct: 344 IHSDLKPANFMLVAGNL-KLIDFGIANTLQQDKTSVLKDSRVGTPSYMSPEAIMAACDDS 168
Query: 390 ----------------RFTIKSDVWSFGILLTELVTKGRVPYPGMNN 420
+ ++SDVWS G +L +V GR P+ + N
Sbjct: 167 ADDSMEEDGHRTKPKYKVGVRSDVWSLGCILYNMVY-GRTPFQHIKN 30
>37602
Length = 804
Score = 40.4 bits (93), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 23/77 (29%), Positives = 37/77 (48%)
Frame = -1
Query: 281 VSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLR 340
+ E ++I EY GS+ D L P + + + G+ Y+ R +HRD++
Sbjct: 309 LRREKLWIAMEYCGGGSMQDIYH--VTGPLTEPQIAFVCRETLKGLHYLHRRGKMHRDIK 136
Query: 341 SANILVGNGLICKIADF 357
ANIL+ K+ADF
Sbjct: 135 GANILLTEEGDVKLADF 85
>18481
Length = 437
Score = 39.7 bits (91), Expect = 0.003, Method: Composition-based stats.
Identities = 21/65 (32%), Positives = 37/65 (56%), Gaps = 3/65 (4%)
Frame = -1
Query: 308 RALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICK---IADFGLARLIE 364
R L ++ ++ Q+ + + +I + +IHRDL+ N L+G G C I DFGL++ +
Sbjct: 212 RRFTLKTILMVSDQLLSRLEFIHQKCFIHRDLKPDNFLMGLGRHCHRLYIIDFGLSKRYK 33
Query: 365 DNEYT 369
D + T
Sbjct: 32 DTQGT 18
>32000
Length = 644
Score = 39.7 bits (91), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 35/112 (31%), Positives = 54/112 (48%), Gaps = 3/112 (2%)
Frame = -1
Query: 353 KIADFGLARL--IEDNEYTARQGAKFPIKWTAPEAALYGRF-TIKSDVWSFGILLTELVT 409
KIADFGLAR+ + YT + + APE L RF ++ D+WS G + E++T
Sbjct: 569 KIADFGLARVFGLPVRTYTHEVIT---LWYRAPEILLGCRFYSVPVDIWSLGCIFVEMMT 399
Query: 410 KGRVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKKDPEERPTF 461
+ R +PG + + L ++ R P + P K P+ +PTF
Sbjct: 398 R-RALFPGDSEIDQLYRIFRTLGTPDEKVWPGV---------SKLPDYKPTF 273
>32264
Length = 287
Score = 39.7 bits (91), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 18/44 (40%), Positives = 29/44 (65%)
Frame = +1
Query: 427 VERGYRMPCPQDCPISLHELMIHCWKKDPEERPTFEYLQSFLED 470
+E GYR+ P S+++LM+ CW+ PE+RP F+ L + L+D
Sbjct: 1 IEDGYRLQQNPQTPDSVYKLMLRCWEYVPEKRPHFKELYTSLKD 132
>16708
Length = 1397
Score = 38.9 bits (89), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 35/149 (23%), Positives = 74/149 (49%), Gaps = 11/149 (7%)
Frame = -1
Query: 225 LGQGCFAEVWLG-TWNGNTKVAIKTLKPGTMSPESFLEEAQIMKKLKHD-KLVQLY-AVV 281
LG+G F +V+ + + K A+KT ++ L+E + + +++ L Q++ A V
Sbjct: 1379 LGKGVFGKVYEARLLSTHEKAALKT----SILCHHSLDEVEALGRIEGGFYLAQMFGAWV 1212
Query: 282 SEEP---IYIVTEYMNKGSLLDFLKDGEGRALKL----PNLVD-MAAQVAAGMAYIERMN 333
+ P + I+ + G L + + + + + P +V +A Q + +I +
Sbjct: 1211 TCLPFPKMNILLHFYEMGPLCNVYAHYKNKEMPIRWSNPAMVCCIAGQXVCALEHIHELG 1032
Query: 334 YIHRDLRSANILVGNGLICKIADFGLARL 362
+H D+++ N+LV CK+ D+G+A+L
Sbjct: 1031 VVHMDVKADNVLVDAHGNCKLTDYGIAQL 945
>35671
Length = 567
Score = 38.5 bits (88), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 15/47 (31%), Positives = 28/47 (59%)
Frame = -3
Query: 428 ERGYRMPCPQDCPISLHELMIHCWKKDPEERPTFEYLQSFLEDYFTA 474
++G R+ P C +++M+ CW + EERPTF+ L +E+ + +
Sbjct: 565 QKGNRLAKPISCTDEAYKVMLQCWTESREERPTFKKLVPVMENLYRS 425
>00394
Length = 548
Score = 37.7 bits (86), Expect = 0.009, Method: Compositional matrix adjust.
Identities = 29/98 (29%), Positives = 50/98 (51%), Gaps = 11/98 (11%)
Frame = -2
Query: 217 RSLCLEKKLGQGCFAEVWLGTWNGNTKVAI-----KTLKPGTMSPESFLEEAQIMKKLKH 271
R L +K++G+G F V+ G + VA+ + K + F EEA+++K+L+H
Sbjct: 298 RFLKFDKEIGRGSFKTVYKGL-DTELGVAVAWCELQDKKWNKAERQRFKEEAEMLKELQH 122
Query: 272 DKLVQLYAVVSE------EPIYIVTEYMNKGSLLDFLK 303
+V+ + E + I +VTE M G+L +LK
Sbjct: 121 PNIVRFFDYWEEHNHRNRKVIILVTELMTSGTLKTYLK 8
>27405
Length = 532
Score = 37.7 bits (86), Expect = 0.010, Method: Compositional matrix adjust.
Identities = 32/121 (26%), Positives = 52/121 (42%)
Frame = -3
Query: 278 YAVVSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHR 337
YA + E + + + MN G L L + + AA+V G+ ++ ++R
Sbjct: 353 YAFQTPEKLCFILDLMNGGDLHYHLS--QHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYR 180
Query: 338 DLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDV 397
DL+ ANIL+ +I+D GLA + A G + APE + G+ S
Sbjct: 179 DLKPANILLDENGHVRISDLGLACDFSKKKPHASVGTH---GYMAPEVLMKGQAYDSSAD 9
Query: 398 W 398
W
Sbjct: 8 W 6
>38046
Length = 446
Score = 36.6 bits (83), Expect = 0.020, Method: Composition-based stats.
Identities = 15/26 (57%), Positives = 20/26 (76%)
Frame = -1
Query: 322 VAAGMAYIERMNYIHRDLRSANILVG 347
+A MAY+E+ N+IHR+L NILVG
Sbjct: 98 IADAMAYMEKENFIHRNLGDRNILVG 21
>31789
Length = 676
Score = 36.2 bits (82), Expect = 0.031, Method: Compositional matrix adjust.
Identities = 32/121 (26%), Positives = 58/121 (47%), Gaps = 11/121 (9%)
Frame = +2
Query: 217 RSLCLEKKLGQGCFAEVWLGTWNGNTKVAI-----KTLKPGTMSPESFLEEAQIMKKLKH 271
R L + ++G+G F V+ G + VA+ + K + F EEA+++K+L+H
Sbjct: 320 RFLKFDVEIGRGSFKTVYKGL-DTELGVAVAWCELQDKKWNKTERQRFKEEAEMLKELQH 496
Query: 272 DKLVQLYAVVSE------EPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAG 325
+V+ + E + I +VTE M G+L +LK + + L L + Q+ G
Sbjct: 497 PNIVRFFDYWEEHNHRNRKVIILVTELMTSGTLKTYLK--RFKKINLKVLKNWCRQILKG 670
Query: 326 M 326
+
Sbjct: 671 L 673
>21433
Length = 590
Score = 35.8 bits (81), Expect = 0.038, Method: Compositional matrix adjust.
Identities = 25/89 (28%), Positives = 40/89 (44%)
Frame = +2
Query: 321 QVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKW 380
Q+++ + Y IHRD++ N+L+G KIADFG + + T G + +
Sbjct: 191 QLSSALEYCHYRKVIHRDIKPENLLLGLKGDLKIADFGWSVHAPSSRRTTMCGT---LDY 361
Query: 381 TAPEAALYGRFTIKSDVWSFGILLTELVT 409
PE D+WS G+L E +
Sbjct: 362 LPPEMVEGKTHDENVDLWSLGVLCYEFLV 448
>11228
Length = 2155
Score = 35.8 bits (81), Expect = 0.038, Method: Compositional matrix adjust.
Identities = 18/40 (45%), Positives = 25/40 (62%)
Frame = -1
Query: 100 WYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLS 139
WY G+LGR AE L G++L+RESE+ G++ LS
Sbjct: 1972 WYHGRLGRAGAEELLRD--QDAGSYLVRESESKLGSFVLS 1859
Score = 31.6 bits (70), Expect = 0.67, Method: Compositional matrix adjust.
Identities = 26/92 (28%), Positives = 45/92 (48%), Gaps = 1/92 (1%)
Frame = -2
Query: 92 DYEARTEEWYFGK-LGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDWDDMKGDH 150
DYE YF L +++A +L+ G G+FL+R+SE G YSL D
Sbjct: 1491 DYEPVESLPYFHSCLSKEEAVEKLMLAGE--GSFLVRQSENYPGDYSLFFLCEKD----- 1333
Query: 151 VKHYKIRKLDNGGYYITTRAQFETLQQLVQHY 182
V+ ++I + G ++ F++L +++ Y
Sbjct: 1332 VRRFRIER--RGNQFLVGGRLFDSLDGVIKRY 1243
>01392
Length = 1806
Score = 35.8 bits (81), Expect = 0.042, Method: Compositional matrix adjust.
Identities = 32/109 (29%), Positives = 51/109 (46%), Gaps = 12/109 (11%)
Frame = -1
Query: 321 QVAAGMAYIERMNYIHRDLRSANIL---VGNGLICKIADFGLARLIE-DNEYTARQGAKF 376
+A + ++ HRDL+ NIL + + + KI DF LA I D + T
Sbjct: 1767 HIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGISCDGDGTKTPELLT 1588
Query: 377 PI---KWTAPEA--ALYG---RFTIKSDVWSFGILLTELVTKGRVPYPG 417
P+ ++ APE A G + + D+WS GI+L ++ G P+ G
Sbjct: 1587 PVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILYIMLC-GYPPFYG 1444
>18881
Length = 762
Score = 35.4 bits (80), Expect = 0.056, Method: Compositional matrix adjust.
Identities = 22/67 (32%), Positives = 35/67 (52%), Gaps = 2/67 (2%)
Frame = -3
Query: 120 PRGTFLIRESETTKGAYSLSIRDWDDMK--GDHVKHYKIRKLDNGGYYITTRAQFETLQQ 177
P GTFLIR + T S R+ + V+H K+ + G +Y+ F+++QQ
Sbjct: 748 PDGTFLIRVTNT-------SARESCPQY*YANAVRHIKVNRNPQGRFYLADGHYFDSVQQ 590
Query: 178 LVQHYSE 184
LV+HY +
Sbjct: 589 LVEHYEK 569
>07933
Length = 728
Score = 35.0 bits (79), Expect = 0.062, Method: Compositional matrix adjust.
Identities = 13/30 (43%), Positives = 18/30 (60%)
Frame = +3
Query: 436 PQDCPISLHELMIHCWKKDPEERPTFEYLQ 465
P CP L+ +M+ CW +P RPTF L+
Sbjct: 3 PNYCPNLLYNIMMQCWSAEPSARPTFHKLE 92
>37260
Length = 401
Score = 34.3 bits (77), Expect = 0.13, Method: Composition-based stats.
Identities = 17/56 (30%), Positives = 30/56 (53%)
Frame = -1
Query: 100 WYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDWDDMKGDHVKHYK 155
WY+G L ++AE +L+ G+FL+R+S SLS + + ++H+K
Sbjct: 182 WYWGPLSYEEAESKLMD--KRDGSFLVRDSSNENYILSLSFKSMGHVHHTRIEHHK 21
>02638
Length = 1490
Score = 33.9 bits (76), Expect = 0.14, Method: Compositional matrix adjust.
Identities = 25/103 (24%), Positives = 49/103 (47%), Gaps = 7/103 (6%)
Frame = +1
Query: 378 IKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRM---- 433
I + APE + DVWS G ++ E+ T R P+ N+ ++ + +++
Sbjct: 28 IAFMAPEVLRGESYGRACDVWSVGCVMIEMCT-CRPPW---NSHDISNHLALIFKIASSV 195
Query: 434 ---PCPQDCPISLHELMIHCWKKDPEERPTFEYLQSFLEDYFT 473
P P++ + +LM+ C ++D + RP+ + L + FT
Sbjct: 196 DPPPIPENMSPPVRDLMLRCLEQDSDFRPSAKDL--LMHPLFT 318
>29360
Length = 363
Score = 33.5 bits (75), Expect = 0.18, Method: Composition-based stats.
Identities = 28/116 (24%), Positives = 50/116 (43%), Gaps = 7/116 (6%)
Frame = +3
Query: 238 WNGNTK--VAIKTLKPGTMSPESFLEEAQIMKKLKHD-----KLVQLYAVVSEEPIYIVT 290
W T VAIK LK E I+++L + V+ + + +
Sbjct: 12 WKKGTSEIVAIKILKNHPSYARQGQIEVSILQRLSQESADDYNFVRAFECFQHKNHTCLV 191
Query: 291 EYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILV 346
M + +L DFLK + + L L + + QV + ++++ IH DL+ NI++
Sbjct: 192 FEMLEQNLYDFLKQNKFQPLPLKYIRPITQQVLTALRKLKQLGLIHADLKPENIML 359
>06462
Length = 1511
Score = 33.5 bits (75), Expect = 0.21, Method: Compositional matrix adjust.
Identities = 24/85 (28%), Positives = 38/85 (44%)
Frame = +1
Query: 98 EEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDWDDMKGDHVKHYKIR 157
E WY GK+ R++AE+ L G FL+RES + LS + H + +
Sbjct: 1090 ELWYHGKMSRREAEKLL----GKDGDFLVRESGHNXSQFVLSGK-------HHGQFIHLL 1236
Query: 158 KLDNGGYYITTRAQFETLQQLVQHY 182
+D G T F+ + LV ++
Sbjct: 1237 LVDPDGIVRTKDYIFDNISHLVSYH 1311
>24983
Length = 433
Score = 32.3 bits (72), Expect = 0.46, Method: Composition-based stats.
Identities = 17/53 (32%), Positives = 25/53 (47%), Gaps = 6/53 (11%)
Frame = +2
Query: 189 LCFNLTVIASSCTPQTSGLAKDAWEVA------RRSLCLEKKLGQGCFAEVWL 235
+C ++ ASS +P S ++ W V RRS C+ + LG E WL
Sbjct: 203 VCLSVMTTASSMSPNLSKYSRKLWSVV**GXPPRRSWCM*ELLGASDVCERWL 361
>17516
Length = 453
Score = 31.6 bits (70), Expect = 0.78, Method: Compositional matrix adjust.
Identities = 28/101 (27%), Positives = 47/101 (46%), Gaps = 6/101 (5%)
Frame = -3
Query: 382 APEAALY-GRFTIKSDVWSFGILLTELVTKGRVPYPGMNNR---EVLEQVERGYRMPCPQ 437
APE L G++ +K+DV+S I+L EL G+ +++ + + V+ G R
Sbjct: 415 APEVLLQKGQYDMKADVYSLAIILWEL-WYGQDAADHISSHLFGRLEDAVQAGLRPSVTM 239
Query: 438 DC--PISLHELMIHCWKKDPEERPTFEYLQSFLEDYFTATE 476
C P +L+ W+ +RPT F ED+ T+
Sbjct: 238 TCKPPDDWLKLLQSGWEFHASKRPTSRDAAEFFEDFLERTK 116
>18401
Length = 463
Score = 31.2 bits (69), Expect = 1.1, Method: Compositional matrix adjust.
Identities = 18/50 (36%), Positives = 27/50 (54%)
Frame = -3
Query: 380 WTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVER 429
+ APE L ++ DVWS G ++ EL T G + +N+E L +ER
Sbjct: 434 YRAPEVILELGWSHPCDVWSVGCIMFELYT-GYTLFQTHDNKEHLAMMER 288
>23319
Length = 2235
Score = 30.8 bits (68), Expect = 1.2, Method: Compositional matrix adjust.
Identities = 12/45 (26%), Positives = 24/45 (53%)
Frame = +3
Query: 383 PEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQV 427
P+ ++ D+WS G + EL GR +PG ++ + L+++
Sbjct: 3 PDVYXAKMYSTSIDMWSAGCIFAELANAGRPLFPGNDDDDQLKRI 137
>27287
Length = 514
Score = 30.8 bits (68), Expect = 1.3, Method: Compositional matrix adjust.
Identities = 11/30 (36%), Positives = 19/30 (63%)
Frame = -2
Query: 446 LMIHCWKKDPEERPTFEYLQSFLEDYFTAT 475
+M CW++DP +RP+F L L+ T++
Sbjct: 474 IMHSCWQEDPNDRPSFSRLVQELDKMLTSS 385
>29590
Length = 320
Score = 30.4 bits (67), Expect = 1.9, Method: Composition-based stats.
Identities = 13/43 (30%), Positives = 26/43 (60%)
Frame = +3
Query: 380 WTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNRE 422
+ APE Y +I++D+WS G+L ++T P+ G+ +++
Sbjct: 72 YVAPEVLDYEPLSIQTDMWSLGVLSYVMLTACS-PFVGITSKK 197
>36481
Length = 806
Score = 30.0 bits (66), Expect = 2.4, Method: Compositional matrix adjust.
Identities = 26/108 (24%), Positives = 48/108 (44%), Gaps = 6/108 (5%)
Frame = +2
Query: 244 VAIKTLKPGTMSPESFLEEAQIMKKLK----HDK--LVQLYAVVSEEPIYIVTEYMNKGS 297
+A+K +K E+ E +++KL+ H K VQ+ ++ +M S
Sbjct: 446 IALKIIKNVDKYREAAKLEINVLEKLREKDPHAKHMCVQMLDWFDYHGHVCISFHMLGLS 625
Query: 298 LLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANIL 345
+ DFLKD A + + ++ Q+ + ++ H DL+ NIL
Sbjct: 626 VFDFLKDNSYGAYPIEQVRHISYQLCYAVNFLHENQLTHTDLKPENIL 769
>27562
Length = 399
Score = 29.3 bits (64), Expect = 3.5, Method: Composition-based stats.
Identities = 18/54 (33%), Positives = 26/54 (48%), Gaps = 3/54 (5%)
Frame = -1
Query: 421 REVLEQVERGYRMPCPQDCPISLHELMIH-CWKKDPEERPT--FEYLQSFLEDY 471
R + Q+ R P+ C SL E++ WKKDP ER E L F++ +
Sbjct: 222 RVLWTQMRRRGTQIQPRPCSSSLFEIL*ETAWKKDPSERTENDIEILMDFMQHF 61
>18663
Length = 600
Score = 28.5 bits (62), Expect = 6.4, Method: Compositional matrix adjust.
Identities = 20/66 (30%), Positives = 30/66 (45%), Gaps = 10/66 (15%)
Frame = +2
Query: 379 KWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPY--------PGMNNREVLEQV--E 428
+ APE + D W+ G+LL E++ GR P+ P N + L QV E
Sbjct: 23 NYIAPEILRGEDYGFSVDWWALGVLLYEMLA-GRSPFDIAGASENPDQNTEDYLFQVILE 199
Query: 429 RGYRMP 434
+ R+P
Sbjct: 200 KTIRIP 217
>15741
Length = 402
Score = 28.5 bits (62), Expect = 7.1, Method: Composition-based stats.
Identities = 11/32 (34%), Positives = 18/32 (56%)
Frame = -3
Query: 314 NLVDMAAQVAAGMAYIERMNYIHRDLRSANIL 345
+ A VA GMA++ +HRD+ + N+L
Sbjct: 97 DFFSFALHVARGMAHVANNKIVHRDVAARNVL 2
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000346671 | hsapiens_gene_ensembl | Proto-oncogene
tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn) (Protooncogene
Syn) (SLK). [Source:Uniprot/SWISSPROT;Acc:P06241]
(485 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
21808 318 7e-88
06405 300 1e-81
11780 170 2e-62
09007 153 1e-37
04852 147 6e-36
17300 123 2e-33
20640 125 4e-29
07291 122 2e-28
14116 121 5e-28
08294 104 8e-23
07940 102 5e-22
18996 98 6e-21
22005 83 2e-20
01718 94 9e-20
17637 93 2e-19
13592 91 1e-18
14477 86 3e-17
13305 80 2e-15
19301 79 4e-15
01756 77 2e-14
00715 77 2e-14
12721 72 7e-13
17253 70 3e-12
01060 70 3e-12
01707 68 7e-12
18921 67 1e-11
29581 66 4e-11
14126 65 9e-11
00300 64 1e-10
25550 64 2e-10
18484 63 2e-10
14420 62 6e-10
27546 61 1e-09
04591 60 1e-09
00392 59 6e-09
01966 58 7e-09
31885 57 2e-08
13066 57 2e-08
07836 57 2e-08
09606 55 7e-08
03240 55 8e-08
12672 54 1e-07
13212 53 3e-07
04138 52 4e-07
21079 52 7e-07
19094 49 6e-06
29243 49 6e-06
15910 48 1e-05
30755 47 1e-05
26560 46 3e-05
21210 46 4e-05
19761 45 6e-05
11185 45 1e-04
14257 44 1e-04
01106 43 2e-04
28638 42 5e-04
26711 42 8e-04
12786 41 0.001
37602 40 0.001
18481 40 0.003
32000 40 0.003
32264 40 0.003
16708 39 0.004
35671 39 0.006
00394 38 0.009
27405 38 0.010
38046 37 0.020
31789 36 0.031
21433 36 0.038
11228 36 0.038
01392 36 0.042
18881 35 0.056
07933 35 0.062
37260 34 0.13
02638 34 0.14
29360 33 0.18
06462 33 0.21
24983 32 0.46
17516 32 0.78
18401 31 1.1
23319 31 1.2
27287 31 1.3
29590 30 1.9
36481 30 2.4
27562 29 3.5
18663 28 6.4
15741 28 7.1
>21808
Length = 1011
Score = 318 bits (814), Expect(2) = 7e-88, Method: Compositional matrix adjust.
Identities = 152/225 (67%), Positives = 180/225 (80%), Gaps = 1/225 (0%)
Frame = +1
Query: 236 GTWNGNTKVAIKTLKPGTMSPESFLEEAQIMKKLKHDKLVQLYAVVSEE-PIYIVTEYMN 294
G WN T VAIKTLK GTM P+ FL EAQIMKKL+H KL+QLYAV +++ PI+I+TE M
Sbjct: 4 GLWNNTTPVAIKTLKSGTMDPKDFLAEAQIMKKLRHPKLIQLYAVCTQDDPIFIITELMK 183
Query: 295 KGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKI 354
GSLL+FL+ G+GR LKLP L+D+ AQ+A GMAY+E NYIHRDL + NILV + KI
Sbjct: 184 NGSLLEFLQ-GKGRVLKLPALIDIGAQIACGMAYLESQNYIHRDLAARNILVSDNNTVKI 360
Query: 355 ADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVP 414
ADFGLAR+I+++EY AR GA+FPIKWTAPEAA Y RFTIKSDVWSFGILLTE VT GRVP
Sbjct: 361 ADFGLARVIKEDEYEARVGARFPIKWTAPEAANYNRFTIKSDVWSFGILLTETVTYGRVP 540
Query: 415 YPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKKDPEERP 459
YPGM N EVL QVE GYRMPCP CP L+++M+ CW+K+ ERP
Sbjct: 541 YPGMTNAEVLHQVEHGYRMPCPPGCPKPLYDIMLECWRKEEMERP 675
Score = 25.0 bits (53), Expect(2) = 7e-88, Method: Compositional matrix adjust.
Identities = 11/22 (50%), Positives = 14/22 (63%)
Frame = +2
Query: 459 PTFEYLQSFLEDYFTATEPQYQ 480
PTFE LQ LE++FT Y+
Sbjct: 674 PTFETLQWKLEEFFTMDSKDYR 739
>06405
Length = 1965
Score = 300 bits (767), Expect = 1e-81, Method: Compositional matrix adjust.
Identities = 160/350 (45%), Positives = 221/350 (63%), Gaps = 5/350 (1%)
Frame = +1
Query: 128 ESETTKGAYSLSIRDWDDMKGDHVKHYKIRKLDNGGYYITTRAQFETLQQLVQHYSEKAD 187
ESE++ G S+S+R +G V HY+I + D+G ++T +F TL +LV H+S AD
Sbjct: 1 ESESSPGQRSISVR----FEG-RVYHYRITE-DDGKVFVTQEHRFNTLAELVHHHSIHAD 162
Query: 188 GLCFNLTVIASS-CTPQTSGLAK--DAWEVARRSLCLEKKLGQGCFAEVWLGTWNG-NTK 243
GL L A P G++ D WE+ R + ++ +LG G + +V+ W N
Sbjct: 163 GLVTTLLYPAPKRQKPTVFGVSPEPDRWEIERTEIAMKHRLGGGQYGDVYEAMWKRYNKI 342
Query: 244 VAIKTLKPGTMSPESFLEEAQIMKKLKHDKLVQLYAVVSEEP-IYIVTEYMNKGSLLDFL 302
VA+KTLK TM+ FLEEA IMK++KH LVQL V + EP YIVTE+M G+LLD+L
Sbjct: 343 VAVKTLKEDTMALNDFLEEAAIMKEMKHPNLVQLLGVCTREPPFYIVTEFMPHGNLLDYL 522
Query: 303 KDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARL 362
+ L+ MA Q+A+GMAY+E N+IHRDL + N LV + + K+ADFGLARL
Sbjct: 523 RSSTREENGPTALMYMATQIASGMAYLETKNFIHRDLAARNCLVADSNMVKVADFGLARL 702
Query: 363 IEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNRE 422
++D+ YTA GAKFPIKWTAPE + RF+ +SD+W+FG+LL EL T G PYPG+ E
Sbjct: 703 MKDDTYTAHIGAKFPIKWTAPEGLAFNRFSTRSDIWAFGVLLWELATYGMSPYPGVELTE 882
Query: 423 VLEQVERGYRMPCPQDCPISLHELMIHCWKKDPEERPTFEYLQSFLEDYF 472
V +ERGYRM P P ++ LM+ CW+ DP++RPTF+ + LE+ F
Sbjct: 883 VYHLLERGYRMERPPGTPADVYILMLKCWQWDPKDRPTFKEIHFLLENMF 1032
>11780
Length = 1713
Score = 170 bits (431), Expect(2) = 2e-62, Method: Compositional matrix adjust.
Identities = 107/293 (36%), Positives = 156/293 (53%), Gaps = 7/293 (2%)
Frame = +3
Query: 100 WYFGKLGRKDAERQLLSFGNPR--GTFLIRESETTKGAYSLSIRDWDDMKGDHVKHYKIR 157
W+ GK+ R+ AE L PR G FLIRES G Y+L + V+HY+I
Sbjct: 255 WFHGKITRQQAEELL----KPREDGLFLIRESSNYPGDYTLCV-----CHLGKVEHYRIL 407
Query: 158 KLDNGGYYITTRAQFETLQQLVQHYSEKADGLCFNLTVIASS-----CTPQTSGLAKDAW 212
+N I F L +LV+HY ADGLC LT + T W
Sbjct: 408 YRENQ-LTIDEEGFFRNLDELVKHYLADADGLCTQLTRPVTKQGGNFGTVSLQEFKSGGW 584
Query: 213 EVARRSLCLEKKLGQGCFAEVWLGTWNGNTKVAIKTLKPGTMSPESFLEEAQIMKKLKHD 272
+A + L + + +G+G F +V+ G + G VAIK LK +SFL+EA +M L+HD
Sbjct: 585 VIAXQDLEIGEAIGKGDFGDVYKGMYRGQP-VAIKQLKDKDRGEQSFLQEASVMTSLRHD 761
Query: 273 KLVQLYAVVSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERM 332
LV+L VV E I++VTE+M KG+L+++L+ + + ++ A A M Y+E
Sbjct: 762 NLVRLIGVVLGETIFLVTEFMGKGNLVEYLRSRGRSVITKKDQINFATDTCAAMEYLESK 941
Query: 333 NYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEA 385
+HRDL + N+LV + K++DFGLA+ + ++ + KFPIKWTAPEA
Sbjct: 942 RLVHRDLAARNVLVHDDGKAKVSDFGLAKFGDFSQTS----VKFPIKWTAPEA 1088
Score = 87.0 bits (214), Expect(2) = 2e-62, Method: Compositional matrix adjust.
Identities = 41/86 (47%), Positives = 57/86 (66%)
Frame = +1
Query: 390 RFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIH 449
+FT KSD+WSFGILL E+ + GRVPYP + +V+ VERGYRM P+ CP ++ +M
Sbjct: 1102 KFTSKSDMWSFGILLWEIYSFGRVPYPRIPLTDVVMHVERGYRMEAPEGCPPEIYSIMKQ 1281
Query: 450 CWKKDPEERPTFEYLQSFLEDYFTAT 475
W+ DP ERPTF+ + + L + T
Sbjct: 1282 AWELDPNERPTFKSVLARLNNQRAVT 1359
>09007
Length = 1440
Score = 153 bits (387), Expect = 1e-37, Method: Compositional matrix adjust.
Identities = 97/283 (34%), Positives = 151/283 (53%), Gaps = 15/283 (5%)
Frame = -1
Query: 214 VARRSLCLEKKLGQGCFAEVWLGTWNGNT----KVAIKTLKPGTMSP--ESFLEEAQIMK 267
+++ + L K LGQG F V W + +VA+K L + + FL+E IM+
Sbjct: 888 ISKDCVALSKSLGQGHFGTVRQAIWTAESGEKVQVAVKCLSKDKIHKDGQEFLKETAIMQ 709
Query: 268 KLKHDKLVQLYAVVSEE--PIYIVTEYMNKGSLLDFLKDGEGRA-LKLPNLVDMAAQVAA 324
L H+ +V++Y VV + I +VTE SLL+ +K+ R +P L D + QV
Sbjct: 708 MLDHENIVRVYGVVMDNGADIMLVTELAPMRSLLECVKEVSARVDFSVPRLCDFSQQVCD 529
Query: 325 GMAYIERMNYIHRDLRSANILVGNGLICKIADFGLA-RLIEDNEYTARQGA---KFPIKW 380
GM+Y+E +HRDL + NIL+ + KI+D G++ L EY Q + + W
Sbjct: 528 GMSYLESKRLVHRDLAARNILLFSKSKVKISDVGVSGALGAGKEYYQSQQTIHLQNAVAW 349
Query: 381 TAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVE--RGYRMPCPQD 438
APE+ F+ SDVW+FG+LL E T G P+ G+N ++++E V+ + R+ P
Sbjct: 348 CAPESFRNLCFSSASDVWAFGVLLWEFFTHGFQPWAGLNGQQIMEAVDAPQSQRLEQPDL 169
Query: 439 CPISLHELMIHCWKKDPEERPTFEYLQSFLEDYFTATEPQYQP 481
CP + +M+ CW+++P+ RPTF L FL T PQ +P
Sbjct: 168 CPKEYYAVMLKCWEQEPQRRPTFSQL--FL------TLPQIRP 64
>04852
Length = 1462
Score = 147 bits (372), Expect = 6e-36, Method: Compositional matrix adjust.
Identities = 87/259 (33%), Positives = 136/259 (52%), Gaps = 31/259 (11%)
Frame = +1
Query: 242 TKVAIKTLKPGTMSPE--SFLEEAQIMKKLK----HDKLVQLYAVVSEE-PIYIVTEYMN 294
+ VA+K L+ + E F++E Q+MK +K H +V ++ P++++ E+
Sbjct: 22 STVAVKMLRDIVTAVEEQDFVQELQVMKAVKKMGSHINIVNFLGCCTQGGPLWVIVEFAK 201
Query: 295 KGSLLDFL---KDG--------------------EGRALKLPNLVDMAAQVAAGMAYIER 331
G+L DFL +DG G ++ NL+ A Q+A GM ++
Sbjct: 202 NGNLRDFLESCRDGINGYGKFVSPQDPGWYTKTPGGHVIRRKNLLSYAFQIARGMEFLAS 381
Query: 332 MNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRF 391
IHRDL + N+LV + KIADFGL+R + Y R G + P+KW APEA R+
Sbjct: 382 RKCIHRDLAARNVLVTEEHVLKIADFGLSR--TGDYYKKRSGGRLPVKWMAPEALFDMRY 555
Query: 392 TIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQ-VERGYRMPCPQDCPISLHELMIHC 450
T KSDVWSFG++L E+ + G +PY + N E+ + ++ YRMP P+ +L+ +M C
Sbjct: 556 TTKSDVWSFGVVLWEIFSLGGMPYASIPNEELYSKLLDDAYRMPRPELASGNLYAIMERC 735
Query: 451 WKKDPEERPTFEYLQSFLE 469
W P +RP F L ++
Sbjct: 736 WLNRPSDRPEFSQLVGHID 792
>17300
Length = 480
Score = 123 bits (308), Expect(2) = 2e-33, Method: Compositional matrix adjust.
Identities = 56/117 (47%), Positives = 83/117 (70%), Gaps = 4/117 (3%)
Frame = +1
Query: 322 VAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDN----EYTARQGAKFP 377
+++GM + M Y+HRDL + NILV L+CK+ADFGL+R IE + YT + G K P
Sbjct: 1 ISSGMGXLADMGYVHRDLAARNILVNEILVCKVADFGLSREIESDTTEGAYTTK-GGKIP 177
Query: 378 IKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMP 434
++WTAPEA Y +FT SDVWSFG+++ E+++ G PY +N++V++ VE+GYR+P
Sbjct: 178 VRWTAPEAIAYRKFTSASDVWSFGVVMWEVMSYGERPYWNWSNQDVIKAVEKGYRLP 348
Score = 37.7 bits (86), Expect(2) = 2e-33, Method: Composition-based stats.
Identities = 16/43 (37%), Positives = 23/43 (53%), Gaps = 1/43 (2%)
Frame = +2
Query: 435 CPQ-DCPISLHELMIHCWKKDPEERPTFEYLQSFLEDYFTATE 476
CP DCP +LH+LM+ W+K+ RP + L+ A E
Sbjct: 344 CPSMDCPEALHQLMLDAWQKERSHRPKMSMVVKTLDKLIRAPE 472
>20640
Length = 1492
Score = 125 bits (313), Expect = 4e-29, Method: Compositional matrix adjust.
Identities = 59/144 (40%), Positives = 86/144 (59%), Gaps = 1/144 (0%)
Frame = +1
Query: 334 YIHRDLRSANILVGNGLICKIADFGLARLIED-NEYTARQGAKFPIKWTAPEAALYGRFT 392
Y+HRDL + N LVG+ L+ KI+DFGLAR + + Y + PI+W EA LY +F+
Sbjct: 7 YVHRDLATRNCLVGHDLVVKISDFGLARSVHSVDYYRGSEHDAIPIRWMPLEAILYNKFS 186
Query: 393 IKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWK 452
+SDVWSFG++L E+ PY G+ + EV+ V+ G + CP+ P ++ELM CW
Sbjct: 187 TQSDVWSFGVVLWEIFAFALQPYYGLTHEEVVRFVKEGKVLACPERTPPPMYELMKQCWH 366
Query: 453 KDPEERPTFEYLQSFLEDYFTATE 476
+ P RP+F L LE+ + E
Sbjct: 367 RRPATRPSFHTLHKTLENMHSKYE 438
>07291
Length = 833
Score = 122 bits (307), Expect = 2e-28, Method: Compositional matrix adjust.
Identities = 60/167 (35%), Positives = 98/167 (58%), Gaps = 2/167 (1%)
Frame = +1
Query: 307 GRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLA-RLIED 365
+ L + L+D Q+A GMAY++ + +HR+L + N +V +++D+G+ L
Sbjct: 31 SKMLTVVQLLDFGRQIADGMAYLQEVKVVHRNLAARNCIVTEDGRLQLSDYGVTGSLFPQ 210
Query: 366 NEYTARQG-AKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVL 424
+ YTA A+ +KW APE F+ KSDVW+FG++L EL+T+G PYP + N +L
Sbjct: 211 SYYTADDSPARDLVKWMAPETIDNFHFSSKSDVWAFGVVLWELLTRGITPYPDVENSSLL 390
Query: 425 EQVERGYRMPCPQDCPISLHELMIHCWKKDPEERPTFEYLQSFLEDY 471
++ G+RM P+ P ++E+M CW + PE+RP F L L+ +
Sbjct: 391 PYLKEGHRMKKPKQSPEPVYEMMTACWNESPEQRPDFAELNDQLKTF 531
>14116
Length = 1017
Score = 121 bits (304), Expect = 5e-28, Method: Compositional matrix adjust.
Identities = 72/216 (33%), Positives = 120/216 (55%), Gaps = 13/216 (6%)
Frame = -1
Query: 214 VARRSLCLEKKLGQGCFAEVWLGTWN-----GNTKVAIKTL---KPGTMSPESFLEEAQI 265
+ R L + +++G+G F V G G+ VA+KTL P + +SFL+EA I
Sbjct: 645 IDREFLTMGEEIGKGNFGCVKRGFLTLPEQKGDILVAVKTLHNNNPREIELQSFLQEALI 466
Query: 266 MKKLKHDKLVQLYAV---VSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQV 322
MK H ++ L + + + P+ +V +M G LL +++D + + + +L+ +
Sbjct: 465 MKDFHHSNVLTLIGICLNLDDMPL-VVLPFMKHGDLLTYIRDDQHQP-TIKDLIMYGVDI 292
Query: 323 AAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQG--AKFPIKW 380
A GM Y+ + ++HRDL + N ++ K+ADFGLAR I + EY + + AK P+KW
Sbjct: 291 ARGMDYLAGLKFVHRDLAARNCMLDEDFHVKVADFGLARDIYEKEYYSSENKKAKLPVKW 112
Query: 381 TAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYP 416
A E+ G + K+DVWS+G++L EL+T+G P
Sbjct: 111 MALESLEKGNYDSKTDVWSYGVVLWELLTRGSDALP 4
>08294
Length = 1849
Score = 104 bits (259), Expect = 8e-23, Method: Compositional matrix adjust.
Identities = 64/207 (30%), Positives = 100/207 (48%), Gaps = 11/207 (5%)
Frame = +2
Query: 273 KLVQLYAVVSE-EPIYIVTEYMNKGSLLDFL-----KDGEGRALKLPNL-----VDMAAQ 321
+V V E EP +++TEY + G L FL +G GR ++P L + M Q
Sbjct: 890 NIVHFMGVCREAEPHFLITEYCDWGDLKQFLLATRNDNGRGRGTRVPALALSQKLGMGQQ 1069
Query: 322 VAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWT 381
VAAGM + +H DL + N+L+ + + K+A L+ + +EY P++W
Sbjct: 1070 VAAGMEALSNQGLVHGDLAARNVLLTSRMQLKVARPALSGDVYASEYYPLHQRLVPLRWL 1249
Query: 382 APEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPI 441
PE L T DVW+FG+ L E++ +PY M++ EVL ++ D P
Sbjct: 1250 PPEGVLEDSATTCGDVWAFGVFLWEVLQLADLPYRLMSDEEVLRSLQHSQAALDSPDAPP 1429
Query: 442 SLHELMIHCWKKDPEERPTFEYLQSFL 468
+L L+ C + P +RP F + S L
Sbjct: 1430 ALLSLLQRCTAQQPSQRPPFSEICSVL 1510
>07940
Length = 1336
Score = 102 bits (253), Expect = 5e-22, Method: Compositional matrix adjust.
Identities = 79/277 (28%), Positives = 117/277 (42%), Gaps = 70/277 (25%)
Frame = -3
Query: 212 WEVARRSLCLEKKLGQGCFAEVWLGTW------NGNTKVAIKTLKPGTMSPE--SFLEEA 263
WE R L L +LG+G F V G N + VA+K LK E + E
Sbjct: 857 WEFPRERLVLGDRLGEGAFGLVMKGEAMGIFKDNNSVTVAVKMLKEDATDREMMDLIREM 678
Query: 264 QIMKKL-KHDKLVQ----------LYAVVSEEPIYIVTEYMN------------------ 294
++MK + KH ++ LY +V P + +++
Sbjct: 677 EMMKVIGKHKNIINLLGCCTQRGALYVIVEFAPHGNLRDFLKSHRPHGTSYSCIADYEQP 498
Query: 295 -------------------KGSLLDFL-------------KDGEGRALKLPNLVDMAAQV 322
+G+ L F+ + + L +L+ A QV
Sbjct: 497 VITSSSSSFSHPNSASSSAQGTSLGFIPGTSTVSFSTGSHRQDMLKMLTPKDLISYAYQV 318
Query: 323 AAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQ-GAKFPIKWT 381
A GM Y+ IHRDL + N+LV + KIADFGL R ++ +Y + + P+KW
Sbjct: 317 ARGMEYLASKQCIHRDLAARNVLVAEEYVLKIADFGLTRNLQQFDYYRKTTDGRLPVKWM 138
Query: 382 APEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGM 418
APEA ++T KSDVWS+G+LL E+ T G PYP +
Sbjct: 137 APEALFDRKYTSKSDVWSYGVLLWEIFTLGGNPYPSV 27
>18996
Length = 491
Score = 98.2 bits (243), Expect = 6e-21, Method: Compositional matrix adjust.
Identities = 55/136 (40%), Positives = 79/136 (58%), Gaps = 6/136 (4%)
Frame = +2
Query: 335 IHRDLRSANILVGNGLICKIADFGLARLIE-DNEYTARQGAKFPIKWTAPEAALYGRFTI 393
IHRDL + NILV + KI+DFGLA+ D Y PIKW +PEA +F+
Sbjct: 2 IHRDLAARNILVDRSCV-KISDFGLAQFANADGYYYGISQRDIPIKWYSPEAIETCKFSS 178
Query: 394 KSDVWSFGILLTELVTKGRVP--YPG--MNNREVLEQVERGYRMPCPQDCPISLH-ELMI 448
SDVWS+G+ L E+ ++G +P PG + E L ++ +G R+P P+ C ++ ELM
Sbjct: 179 YSDVWSYGVTLFEMFSRGEIPNLLPGHDLTQEEFLNRLRKGERLPKPELCSDFVYSELMR 358
Query: 449 HCWKKDPEERPTFEYL 464
CW + P+ RPTF +
Sbjct: 359 PCWHEMPKSRPTFHQI 406
>22005
Length = 873
Score = 82.8 bits (203), Expect(2) = 2e-20, Method: Compositional matrix adjust.
Identities = 58/194 (29%), Positives = 91/194 (46%), Gaps = 44/194 (22%)
Frame = +1
Query: 259 FLEEAQIMKKLKHDKLVQLYAVVS-EEPIYIVTEYMNKGSLLDFLKDGEGRALKLP---- 313
F EA +M H +V+L V + +P+ ++ E+M+KG L DFL+ LP
Sbjct: 151 FEREASLMADFDHPNIVKLLGVCAIGKPMCLLFEFMSKGDLNDFLRLCSPENYNLPVSRS 330
Query: 314 -NLVD-------------------------------------MAAQVAAGMAYIERMNYI 335
NLV ++ Q++AGMAY+ + +Y+
Sbjct: 331 QNLVVDLEDGLRVEVEAEECEKDTQSEDRDCSGMLXTKDQLYISQQISAGMAYLAQKDYV 510
Query: 336 HRDLRSANILVGNGLICKIADFGLARLIEDNEY-TARQGAKFPIKWTAPEAALYGRFTIK 394
HRDL + + I+DFGLAR + +Y + PI+W EA LY +F+ +
Sbjct: 511 HRDL-ATRTVXSRTT*S*ISDFGLARSVHSVDYYRGSEQDAIPIRWMPLEAILYSKFSTQ 687
Query: 395 SDVWSFGILLTELV 408
SDVWSFG++L E++
Sbjct: 688 SDVWSFGVVLWEIL 729
Score = 34.3 bits (77), Expect(2) = 2e-20, Method: Compositional matrix adjust.
Identities = 15/42 (35%), Positives = 24/42 (57%)
Frame = +3
Query: 414 PYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKKDP 455
PY G+ + EV+ V+ G + P P ++ELM CW++ P
Sbjct: 744 PYYGLTHEEVVNYVKAGKILEQPTKTPHQVYELMKQCWQRRP 869
>01718
Length = 959
Score = 94.4 bits (233), Expect = 9e-20, Method: Compositional matrix adjust.
Identities = 81/266 (30%), Positives = 130/266 (48%), Gaps = 16/266 (6%)
Frame = +3
Query: 223 KKLGQGCFAEVWLGTWNGNTKVAIKTLKPGTMSPESFLEEAQIMKKLKHDKLVQLYAV-V 281
+K+G G F+EV+ T +V + T + + L E Q++ +L+H +++ V V
Sbjct: 165 EKIGAGFFSEVFKVTHRITGQVMALKMNTMTSNRHNMLREVQLLNRLQHANILRFMGVCV 344
Query: 282 SEEPIYIVTEYMNKGSLLDFLKDGEGRALKLP--NLVDMAAQVAAGMAYIERMNYIHRDL 339
E ++ +TEY+ G+L L E + +LP + + +A G+ Y+ +IHRDL
Sbjct: 345 HEGQLHALTEYIPSGNLEQLL---EKKDEELPWTQRIQLTLGLARGLDYLHSTRFIHRDL 515
Query: 340 RSANILV----GNGLICKIADFGLARLIE---DNEYTARQGAKFPIKWTAPEAALYGRF- 391
S NIL+ +G IADFGLA I D E G+ + W APE L G F
Sbjct: 516 TSKNILIRREDNHGYHAVIADFGLATKIPDPLDKEKLPTVGSPY---WMAPE-VLNGHFY 683
Query: 392 TIKSDVWSFGILLTELVTKGRVP-----YPGMNNREVLEQVERGYRMPCPQDCPISLHEL 446
++D++S GI++ E+ R+P P MNN V + V + CP+ +L
Sbjct: 684 NERADLFSVGIIMCEIT--ARIPADPDIMPRMNNFGV-DYVALSEMI---SYCPLDYLQL 845
Query: 447 MIHCWKKDPEERPTFEYLQSFLEDYF 472
C + DP++RP + +LE F
Sbjct: 846 AFKCCQVDPQKRPRGVEIIEWLEKIF 923
>17637
Length = 447
Score = 93.2 bits (230), Expect = 2e-19, Method: Compositional matrix adjust.
Identities = 46/132 (34%), Positives = 74/132 (56%), Gaps = 1/132 (0%)
Frame = +1
Query: 343 NILVGNGLICKIADFGLARLIEDNEYTARQGAKF-PIKWTAPEAALYGRFTIKSDVWSFG 401
N ++ + L K+ D L+R + +Y ++ PIKW + EA + SDVWSFG
Sbjct: 1 NCVIDDQLRVKLTDSALSRDLFSGDYNCLGDGEYRPIKWLSLEALQKSHYNEGSDVWSFG 180
Query: 402 ILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKKDPEERPTF 461
+L+ E+ T G++PY ++ E+ ++ GYR+ P +CP L +M +CW P ERP+F
Sbjct: 181 VLMWEMCTLGKLPYAEIDPYEMEHYLKDGYRLAQPFNCPDELFTIMAYCWASMPAERPSF 360
Query: 462 EYLQSFLEDYFT 473
LQ L ++ T
Sbjct: 361 SQLQICLSEFHT 396
>13592
Length = 980
Score = 90.5 bits (223), Expect = 1e-18, Method: Compositional matrix adjust.
Identities = 69/252 (27%), Positives = 130/252 (51%), Gaps = 17/252 (6%)
Frame = +2
Query: 224 KLGQGCFAEVWLGTWNGNTKV-AIK--TLKPG-TMSPESFLEEAQIMKKLKHDKLVQLYA 279
K+GQG F +V+ N ++ A+K ++PG T + ++ EE +I++ +KH LV+ Y
Sbjct: 5 KIGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETRALKNVAEELKILEGIKHKNLVRYYG 184
Query: 280 V-VSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVD--MAAQVAAGMAYIERMNYIH 336
+ V E + I E ++G+L ++ G LP + AQ+ +G+A + + +H
Sbjct: 185 IEVHREELLIFMELCSEGTLESLVELTGG----LPEALSRRFTAQLLSGVAELHKHGIVH 352
Query: 337 RDLRSANILVGNGL-ICKIADFGLARLIEDNE--------YTARQGAKFPIKWTAPEAAL 387
RD+++ANI + +G K+ DFG A I+ + Y Q P +T +
Sbjct: 353 RDIKTANIFLVDGSNSLKLGDFGSAVKIQAHTTVPGELQGYVGTQAYMAPEVFTKTNSDG 532
Query: 388 YGRFTIKSDVWSFGILLTELVTKGRVPYPGMN-NREVLEQVERGYRMPCPQDCPISLHEL 446
+GR +D+WS G ++ E+ + G+ P+ + N +++ +V G + P+ H+
Sbjct: 533 HGRL---ADIWSVGCVVVEMAS-GKRPWAQFDSNFQIMFKVGMGEKPQAPESLSQEGHDF 700
Query: 447 MIHCWKKDPEER 458
+ HC + DP++R
Sbjct: 701 IDHCLQHDPKQR 736
>14477
Length = 493
Score = 86.3 bits (212), Expect = 3e-17, Method: Compositional matrix adjust.
Identities = 55/160 (34%), Positives = 89/160 (55%), Gaps = 8/160 (5%)
Frame = -1
Query: 222 EKKLGQGCFAEVWLGTWNGNTK---VAIKTLKPGTMSPE---SFLEEAQIMKKLKHDKLV 275
E KLG G F V G + + VAIK LK + P ++EA++MKK+ H +V
Sbjct: 475 ELKLGAGNFGSVMKGVCRLDDREIPVAIKVLKNADLDPSVQSELIKEAEVMKKMDHMHIV 296
Query: 276 QLYAVVSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYI 335
+L + E + +V E G L FL + + L L N++++ QV+ GM Y+E ++
Sbjct: 295 RLIGLCEGETMMLVLELAKLGPLNKFLP--KNKHLPLWNILELMWQVSQGMEYLEANKFV 122
Query: 336 HRDLRSANILVGNGLICKIADFGLARLI--EDNEYTARQG 373
HRDL + NIL+ + KI+DFG+++ + E+N Y A++
Sbjct: 121 HRDLAARNILLCDEHFAKISDFGMSKTLSRENNYYMAQEA 2
>13305
Length = 549
Score = 79.7 bits (195), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 35/102 (34%), Positives = 59/102 (57%), Gaps = 4/102 (3%)
Frame = +2
Query: 373 GAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYR 432
+ PI+W A E+ +T +SDVWSFG++L E+ T G PY + +++ ++ GYR
Sbjct: 2 STRVPIRWMAVESLFNNTYTTQSDVWSFGVVLWEIFTLGGTPYSSTDTQQLFAFLKDGYR 181
Query: 433 MPCPQDCPISLHELMIHCWKKDPEERPTFE----YLQSFLED 470
+ P+ C + + +M+ CW ++ + RPTF LQ L+D
Sbjct: 182 LKRPKLCDQNTYAMMLQCWNENAQRRPTFPELCGRLQRMLDD 307
>19301
Length = 712
Score = 79.0 bits (193), Expect = 4e-15, Method: Compositional matrix adjust.
Identities = 50/153 (32%), Positives = 81/153 (52%), Gaps = 3/153 (1%)
Frame = +2
Query: 209 KDAWEVARRSLCLEKKLGQGCFAEVWLGTWNGNTKVAIKTLKPGTMSPESFLEEAQI--M 266
+D WE+ S+ + LG G V+LG +VA+K ++ ++E I +
Sbjct: 281 QDDWEIPFESITDLEWLGSGAQGAVFLGKLCAE-EVAVKKVRD--------IKETDIRNL 433
Query: 267 KKLKHDKLVQLYAVVSEEPIY-IVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAG 325
+KL H ++ V ++ P Y I+ EY G L + L+DG+ L ++D + Q+A+G
Sbjct: 434 RKLNHPNIISFKGVCTQAPCYCIIMEYCPYGQLYEVLRDGKEIPPAL--VLDWSKQIASG 607
Query: 326 MAYIERMNYIHRDLRSANILVGNGLICKIADFG 358
M Y+ IHRDL+S N+LV + KI+DFG
Sbjct: 608 MNYLHSHKIIHRDLKSPNVLVAKNDVVKISDFG 706
>01756
Length = 1858
Score = 77.0 bits (188), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 60/212 (28%), Positives = 94/212 (44%), Gaps = 22/212 (10%)
Frame = -3
Query: 224 KLGQGCFAEVWLGTWNGNTKVAIKTLKPGTMS------PESFLEEAQIMKKLKHDKLVQL 277
K+GQG F EV+ +V +K M P + L E +I++ L H+ +V L
Sbjct: 1721 KIGQGTFGEVFKARCKKTKQVV--AMKKVLMDNEKEGFPITALREIKILQLLNHENVVDL 1548
Query: 278 YAVVSEEP---------IYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAY 328
+ S + Y+V E+ L L LP + ++ Q+ G+ Y
Sbjct: 1547 IEICSTKATSANRYKSMFYLVFEFCEHD--LAGLLSNMSVVFNLPEIKEVMKQLMNGLYY 1374
Query: 329 IERMNYIHRDLRSANILVGNGLICKIADFGLAR-----LIEDNEYTARQGAKFPIKWTAP 383
I R +HRD+++ANIL+ + K+ADFGLAR L + N YT R W P
Sbjct: 1373 IHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNR----VVTLWYRP 1206
Query: 384 EAALYG--RFTIKSDVWSFGILLTELVTKGRV 413
L G ++ D W G ++ E+ T+ +
Sbjct: 1205 PELLLGDRNYSTAIDQWGAGCIMAEMWTRNPI 1110
>00715
Length = 1788
Score = 76.6 bits (187), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 62/223 (27%), Positives = 103/223 (46%), Gaps = 31/223 (13%)
Frame = +1
Query: 269 LKHDKLVQLYAVVS----EEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAA 324
L+H +V + S E+ ++ EY+ +L L D + + + + +A Q+A
Sbjct: 97 LRHVNVVSILGATSLHRFEDGAWLAMEYVGPLNLQTILNDHQ-QDIDSSMRLSLALQMAR 273
Query: 325 GMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLI----------------EDNEY 368
G+ Y+ +N +H DL+ AN L+ L +IADFG + + E
Sbjct: 274 GLHYLHSINIVHLDLKPANCLLTRDLKLRIADFGCCHQLTPTGLDMGEREGGMAGNELEL 453
Query: 369 TARQGA-----KFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREV 423
T QGA + + APE + +++SDV+S GI L ++ T+ + PY G+ V
Sbjct: 454 TPVQGAWKNELAGTLAYRAPELLKGLQPSVRSDVYSLGITLWQMCTR-QGPYEGVPAHAV 630
Query: 424 LEQVERGYRMPCP----QDCP--ISLHELMIHCWKKDPEERPT 460
+ QV PCP +D P + +L CW + E+RPT
Sbjct: 631 VYQVVSKDLRPCPPPSTEDDPFEVMFRDLYTQCWARRVEDRPT 759
>12721
Length = 821
Score = 71.6 bits (174), Expect = 7e-13, Method: Compositional matrix adjust.
Identities = 51/217 (23%), Positives = 100/217 (46%), Gaps = 3/217 (1%)
Frame = +1
Query: 224 KLGQGCFAEVWLGTWNGNTKVAIKTLKPGTMSPESFL-EEAQIMKKLKHDKLVQLYA--V 280
K+G+G V + T ++A+K + L E +M+ H +V++Y +
Sbjct: 109 KIGEGSTGIVCIATSRDGRQMAVKKMDLRKQQRRELLFNEVVVMRDYHHPNIVEMYNSYL 288
Query: 281 VSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLR 340
V++E +++V E+M G+L D + + +++ + + +A++ IHRD++
Sbjct: 289 VNDE-LWVVMEFMEGGALTDIVTNNRMDEVQIATVCRACLK---ALAFLHANGVIHRDIK 456
Query: 341 SANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSF 400
S +IL+ + K+ DFG + + + P W APE + + D+WS
Sbjct: 457 SDSILLSHDGKVKLXDFGFCAQVTQDLQKRKSLVGTPY-WMAPEVISRLPYGPEVDIWSL 633
Query: 401 GILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQ 437
GI++ E++ P N L+ + R MP P+
Sbjct: 634 GIMVMEMIDAE----PPFFNEPPLQAMRRIRDMPPPK 732
>17253
Length = 483
Score = 69.7 bits (169), Expect = 3e-12, Method: Composition-based stats.
Identities = 45/153 (29%), Positives = 69/153 (45%), Gaps = 16/153 (10%)
Frame = -1
Query: 244 VAIKTLKPGTMSPE--SFLEEAQIMKKL-KHDKLVQLYAVVS-EEPIYIVTEYMNKGSLL 299
VA+KT E FL E IM+KL +H +V + +P I+ E+ G LL
Sbjct: 459 VAVKTHNEAATDAEKSEFLRELSIMRKLPRHPNVVSFMGCCTMSDPALILMEFCCHGDLL 280
Query: 300 DFLKD----------GEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNG 349
FL+ L + A VA GMA++ +HRD+ + N+L+
Sbjct: 279 SFLRKRRPDRTVFLTSTANDLTARDFFSFALHVARGMAHVANNKIVHRDVAARNVLISER 100
Query: 350 LICKIADFGLARLIEDNE--YTARQGAKFPIKW 380
+CK++DFGL+R + D Y P++W
Sbjct: 99 NVCKVSDFGLSRRVGDQNDVYEIVSRRPLPLRW 1
>01060
Length = 1800
Score = 69.7 bits (169), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 62/255 (24%), Positives = 117/255 (45%), Gaps = 13/255 (5%)
Frame = +1
Query: 212 WEVARRSLCLEKKLGQGCFAEVW------LGTWNGNTKVAIKTLKPGTMSPESFLEEAQI 265
+E A L +K+G+G + V+ G K+ ++ + G P S + E +
Sbjct: 58 FETALSDLTDFQKIGEGTYGVVYKCRHRATGRKLAMKKIRLRGSEDGV--PSSAIREIAM 231
Query: 266 MKKLKHDKLVQLYAVVSE-EPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAA 324
+++L+H +V L V+ E E +++V E+++ + K EG L + Q+
Sbjct: 232 LRELRHTNIVCLEDVIMEDERLFLVFEFLSMDLKMYIDKFPEGVVLDRRLVKSYVFQIVT 411
Query: 325 GMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPE 384
G+ + + +HRDL+ N+L+ + KIADFG+AR A + + APE
Sbjct: 412 GIXFCHQRRIVHRDLKPQNLLINHTGAIKIADFGMARTFA-LPVRAYTHEVVTLWYRAPE 588
Query: 385 AAL-YGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPISL 443
+ +++ DVWS G + +++ + + + G + + L ++ R P Q P
Sbjct: 589 ILMGASKYSTPVDVWSIGTIFADMLIRTPI-FKGDSEIDQLFKIFRIIGTPTEQTWP-EF 762
Query: 444 HEL-----MIHCWKK 453
H+L M WK+
Sbjct: 763 HKLPAFNGMFPLWKE 807
>01707
Length = 757
Score = 68.2 bits (165), Expect = 7e-12, Method: Compositional matrix adjust.
Identities = 63/216 (29%), Positives = 110/216 (50%), Gaps = 10/216 (4%)
Frame = +1
Query: 224 KLGQGCFAEVWLGTWNGNTK--VAIKTLKPGTMSP---ESFLEEAQIMKKLKHDKLVQLY 278
K+G+G + V+ N T VAIK P + + E +++K+LKH LV+L
Sbjct: 85 KIGEGSYGVVF-KCRNKETSQLVAIKKFVESEDDPLIKKIAMREIRMLKQLKHPNLVRLI 261
Query: 279 AVVSEEP-IYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHR 337
V + +++V +Y++ +LL+ L D R L P + + Q + + + N IHR
Sbjct: 262 EVFRRKKRLHLVFDYVDH-TLLNEL-DRYPRGLPEPMVKRIIYQTLLAVNFCHQYNTIHR 435
Query: 338 DLRSANILVGNGLICKIADFGLARLIE--DNEYTARQGAKFPIKWTAPEAALYG--RFTI 393
D++ NIL+ K+ DFG AR++ +EYT ++ + APE L G ++
Sbjct: 436 DVKPENILITRQGQVKLCDFGFARILTGPGDEYTDYVATRW---YRAPE-LLVGDTQYGP 603
Query: 394 KSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVER 429
DVW+ G + EL+T G+ +PG ++ + L + +
Sbjct: 604 PVDVWAIGCVFAELLT-GQALWPGRSDVDQLHLIRK 708
>18921
Length = 697
Score = 67.4 bits (163), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 53/193 (27%), Positives = 89/193 (46%), Gaps = 2/193 (1%)
Frame = +2
Query: 224 KLGQGCFAEVWLGTWNGNTKV-AIKTLKPGTMSPESFLEEAQIMKKLKHDKLVQLY-AVV 281
KLG+G + V+ +V AIK + P + ++E IM++ +V+ Y +
Sbjct: 50 KLGEGSYGSVFKSLHKETGQVLAIKQV-PVDTDLQEIIKEISIMQQCDSKYIVKYYGSYF 226
Query: 282 SEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRS 341
++IV EY GS+ D ++ + L + + G+ Y+ IHRD+++
Sbjct: 227 KNTDLWIVMEYCGAGSVSDIMR-LRNKTLVEREIATILYYTLKGLXYLHSRRKIHRDIKA 403
Query: 342 ANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFG 401
NIL+ N K+ADFG+A + D P W APE + +D+WS G
Sbjct: 404 GNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTPY-WMAPEVIQEIGYDCVADIWSLG 580
Query: 402 ILLTELVTKGRVP 414
I E+ +G+ P
Sbjct: 581 ITALEM-AEGKPP 616
>29581
Length = 1278
Score = 65.9 bits (159), Expect = 4e-11, Method: Compositional matrix adjust.
Identities = 59/191 (30%), Positives = 91/191 (47%), Gaps = 11/191 (5%)
Frame = -2
Query: 249 LKPGTMSPESFLEEAQIMKKLKHDKLVQLYAVV---SEEPIYIVTEYMNK--GSLLDFLK 303
L+ +SP + + L+H +VQL VV S + +++V EY + SLLD +
Sbjct: 1244 LERDMVSPSVVCVRSTFLLNLRHQNIVQLQEVVVGKSLDSLFLVMEYCEQDLASLLDNMP 1065
Query: 304 DGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLI 363
+ + + Q+ G+ Y+ IHRDL+ +N+L+ + KIADFGLAR
Sbjct: 1064 APFSES----QVKCIVLQLLKGLRYLHEAFIIHRDLKVSNLLMTDKGCVKIADFGLAR-- 903
Query: 364 EDNEYTARQGAKFP----IKWTAPEAALYGRFTIKS--DVWSFGILLTELVTKGRVPYPG 417
Y Q P + + APE L+G T + D+WS G +L EL+ P
Sbjct: 902 ---NYGKPQKPMTPKVVTLWYRAPE-LLFGSKTHSTAIDMWSAGCILGELLGHK----PL 747
Query: 418 MNNREVLEQVE 428
M R L+Q+E
Sbjct: 746 MPGRSDLQQIE 714
>14126
Length = 1265
Score = 64.7 bits (156), Expect = 9e-11, Method: Compositional matrix adjust.
Identities = 64/272 (23%), Positives = 124/272 (45%), Gaps = 23/272 (8%)
Frame = +3
Query: 196 IASSCTPQ-TSGLAKDAWEVARRSLCLEKK------LGQGCFAEVWLG--TWNGNTKVAI 246
+ ++ +P+ G ++ A +++RR E+K +G G + V+ N VA+
Sbjct: 105 MKTAISPKGRDGQSESAAKMSRRRDSTEQKYEEVAVIGNGAYGTVYKARDLRNQGEFVAM 284
Query: 247 KTLKPGTMS---PESFLEEAQIMKKLK---HDKLVQLYAVV------SEEPIYIVTEYMN 294
K ++ P + E ++K+L+ H +V+L V E + +V EY+
Sbjct: 285 KRIRLNNTEEGMPMMAIREISMLKQLEQYEHPNVVRLLDVSHNTITDREIRLNLVFEYI- 461
Query: 295 KGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKI 354
+ L +L L + D+ Q+ G+ ++ +HRDL+ N+L+ K+
Sbjct: 462 EHDLATYLAKCPSPGLGPDRIKDLMLQLLNGVDFLHSNRIVHRDLKPQNLLISKDGRLKL 641
Query: 355 ADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVP 414
ADFGLAR+ + + A + + +PE + + D+WS G + EL T+ R
Sbjct: 642 ADFGLARIY--SFHMALTTVVVTLWYRSPEVLMQAEYGTSVDIWSCGCIFAELFTR-RAL 812
Query: 415 YPGMNNREVLEQVERGYRMPCPQDCP--ISLH 444
+ G + + L+++ +P D P +S+H
Sbjct: 813 FKGSSEFDQLKKIFEVIGLPPAGDWPEGVSVH 908
>00300
Length = 2318
Score = 63.9 bits (154), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 57/251 (22%), Positives = 118/251 (47%), Gaps = 16/251 (6%)
Frame = -1
Query: 224 KLGQGCFAEVWLGT-WNGNTKVAIKTLK--PGTMSP-ESFLEEAQIMKKLKHDKLVQLYA 279
K+G+G F +V+ + +A+K +K P + +E +I + ++H+ LV+ Y
Sbjct: 1637 KIGEGQFGKVYTAVNMSTGELMALKEMKFQPNDLQQLREMCDEIKIFEGIQHENLVKYYG 1458
Query: 280 V-VSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPN--LVDMAAQVAAGMAYIERMNYIH 336
V V ++ + + EY + G++ + K G LP + ++ + ++ + +H
Sbjct: 1457 VEVHKDEMLMFMEYCDTGTIEEAAKMG------LPEYLIRRYTREIVLAVNHLHENSIVH 1296
Query: 337 RDLRSANILVGNGLICKIADFGLARLIEDN-----EYTARQGAK---FPIKWTAPEAALY 388
RD++ ANI + + K+ DFG + ++ + E+ G P +T + Y
Sbjct: 1295 RDIKGANIFLTSNGHVKLGDFGCSVKLKSHTTMPGEFHNLVGTTAYMAPEVFTQNDQGGY 1116
Query: 389 GRFTIKSDVWSFGILLTELVTKGRVPYPGM-NNREVLEQVERGYRMPCPQDCPISLHELM 447
GR +D+WS G ++ E+ T G+ P+ + NN +++ +V G++ P + +
Sbjct: 1115 GR---AADIWSLGCVVIEMAT-GKRPWHDLDNNYQIMYKVGIGHKPAVPDSLSVEGKHFL 948
Query: 448 IHCWKKDPEER 458
DP +R
Sbjct: 947 DLIMCHDPAQR 915
>25550
Length = 941
Score = 63.5 bits (153), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 29/63 (46%), Positives = 41/63 (65%)
Frame = +3
Query: 413 VPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKKDPEERPTFEYLQSFLEDYF 472
V YPG++ EV +ERGYRM PQ P ++ LM+ CW+ DP+ERPTF+ + LE+ F
Sbjct: 36 VXYPGVDLTEVYHLLERGYRMERPQGTPADVYILMLKCWQWDPKERPTFKEIHYLLENMF 215
Query: 473 TAT 475
+
Sbjct: 216 EKS 224
>18484
Length = 635
Score = 63.2 bits (152), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 37/122 (30%), Positives = 65/122 (53%)
Frame = +1
Query: 306 EGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIED 365
EG+ K P AA++A G+ ++ I+RDL+ N+++ + KIADFG+ +
Sbjct: 25 EGK-FKEPVAAFYAAEIAVGLFFLHDQGIIYRDLKLDNVMLDSEGHIKIADFGMCKEGMT 201
Query: 366 NEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLE 425
+ T R P + APE LY ++ D W++G+LL E++ G+ P+ G + E+
Sbjct: 202 GDATTRTFCGTP-DYIAPEIVLYQPYSKSVDWWAYGVLLFEMLA-GQPPFDGEDEDELFS 375
Query: 426 QV 427
+
Sbjct: 376 SI 381
>14420
Length = 528
Score = 62.0 bits (149), Expect = 6e-10, Method: Compositional matrix adjust.
Identities = 40/166 (24%), Positives = 80/166 (48%), Gaps = 3/166 (1%)
Frame = +2
Query: 257 ESFLEEAQIMKKLKHDKLVQ-LYAVVSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNL 315
E + E +M++ ++ +V L + + E +++V E++ GSL D + + + +
Sbjct: 35 ELIINEILVMRENQNPNIVNYLDSYLVGEELWVVMEFLAGGSLTDVVTE---TCMDEGQI 205
Query: 316 VDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLI--EDNEYTARQG 373
+ + + ++ IHRD++S NIL+G K+ DFG + E ++ + G
Sbjct: 206 AAVCRECLQALEFLHENQVIHRDIKSDNILLGMDGSVKLTDFGFCAQLSPEQSKRSTMVG 385
Query: 374 AKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMN 419
+ W APE ++ D+WS G++ E++ +G PY N
Sbjct: 386 TPY---WMAPEVVTRKQYGPTVDIWSLGVMCIEMI-EGEPPYLNEN 511
>27546
Length = 426
Score = 61.2 bits (147), Expect = 1e-09, Method: Composition-based stats.
Identities = 36/114 (31%), Positives = 56/114 (49%), Gaps = 7/114 (6%)
Frame = -1
Query: 259 FLEEAQIMKKLKHDKLVQLYAVVSEEP-IYIVTEYMNKGSLLDFLKDGEGRALKLPNLVD 317
F E +I+ +L H ++Q+++++ P I+I Y KG +L +K +D
Sbjct: 339 FPRELEILTRLDHPNIIQIHSILQRGPKIFIFMRYAEKGDMLSHIKK--------TGPID 184
Query: 318 MAA------QVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIED 365
A Q+A + Y+ + HRDL+ NIL+ L KIADFG AR D
Sbjct: 183 EAQTKVWFFQMAKALQYLHSHDIAHRDLKCENILLSKRLNVKIADFGFARYCRD 22
>04591
Length = 1117
Score = 60.5 bits (145), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 44/169 (26%), Positives = 83/169 (49%), Gaps = 14/169 (8%)
Frame = -2
Query: 256 PESFLEEAQIMKKLKHDKLVQLYAVVSEEP---------IYIVTEYMN--KGSLLDFLKD 304
P + L E +I+++L+H+ +VQL + + Y++ EY + LL+ L+
Sbjct: 1089 PITALREIKILQQLEHENVVQLQEICHTQAGPYNRYKSTFYLIFEYCDYDLAGLLNNLR- 913
Query: 305 GEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLAR-LI 363
L + ++ +Q+ G+ YI +HRD+++ANIL+ + K+ADFGL+R +
Sbjct: 912 ---VKFSLADKKNLMSQLLNGLFYIHTKQILHRDIKAANILLTRDGVLKLADFGLSRPWV 742
Query: 364 EDNEYTARQGAKFPIKWTAPEAALYG--RFTIKSDVWSFGILLTELVTK 410
+ T R W P L G + + D+W G ++ E+ ++
Sbjct: 741 KSKRLTNR----VVTLWYRPPELLLGEREYGPEIDMWGVGCIMAEMWSR 607
>00392
Length = 668
Score = 58.5 bits (140), Expect = 6e-09, Method: Compositional matrix adjust.
Identities = 53/174 (30%), Positives = 88/174 (50%), Gaps = 10/174 (5%)
Frame = +3
Query: 257 ESFLEEAQIMKKLKHDKLVQLYAVVSE------EPIYIVTEYMNKGSLLDFLKDGEGRAL 310
+ F EEA+++K+L+H +V+ + E + I +VTE M G+L +LK + +
Sbjct: 66 QRFKEEAEMLKELQHPNIVRFFDYWEEHNHRNRKVIILVTELMTSGTLKTYLKRFKKPNV 245
Query: 311 KLPNLVDMAAQVAAGMAYIERMN--YIHRDLRSANILV-GNGLICKIADFGLARLIEDNE 367
K+ L + QV G+ ++ IHRDL+ NI + G KI D GLA L N+
Sbjct: 246 KI--LKNWCRQVLKGLYFLHTRTPPVIHRDLKCDNIFITGPTGSVKIGDLGLATL--KNQ 413
Query: 368 YTARQGAKFPIKWTAPEAALY-GRFTIKSDVWSFGILLTELVTKGRVPYPGMNN 420
A+ P ++ APE +Y + DV++FG+ + E+ + PY +N
Sbjct: 414 SFAKSVIGTP-EFMAPE--MYEEHYDEAVDVYAFGMCMLEMAS-SEYPYSECSN 563
>01966
Length = 1735
Score = 58.2 bits (139), Expect = 7e-09, Method: Compositional matrix adjust.
Identities = 32/107 (29%), Positives = 58/107 (54%), Gaps = 1/107 (0%)
Frame = -1
Query: 256 PESFLEEAQIMKKLKHDKLVQLYAVVSE-EPIYIVTEYMNKGSLLDFLKDGEGRALKLPN 314
P S + E ++++L+H +V L V+ E E +++V E+++ + K EG L
Sbjct: 1582 PSSAIREIAMLRELRHTNIVCLEDVIMEDERLFLVFEFLSMDLKMYIDKFPEGVVLDRRL 1403
Query: 315 LVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLAR 361
+ Q+ G+ + + +HRDL+ N+L+ + KIADFG+AR
Sbjct: 1402 VKSYVFQIVTGINFCHQRRIVHRDLKPQNLLINHTGAIKIADFGMAR 1262
>31885
Length = 529
Score = 57.0 bits (136), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 46/169 (27%), Positives = 78/169 (46%), Gaps = 6/169 (3%)
Frame = -2
Query: 263 AQIMKKLKHDKLVQL-YAVVSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQ 321
++ +L H LV L YA EE +++V + G L ++ + + + + Q
Sbjct: 519 VDMLTRLDHPFLVNLWYAFQDEEDLFMVVDLFLGGDLRYHMQ--QEVSFREDCVKFYLCQ 346
Query: 322 VAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWT 381
+A + Y+ +HRD++ NIL+ C + DF +A +ED+E P +
Sbjct: 345 LALVLDYLRSQKIVHRDIKPDNILLDEQGHCHVTDFNIATQLEDDELATSTSGTRP--YM 172
Query: 382 APE---AALYGR--FTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLE 425
APE A+ R + D WS G+ L EL+ K R P+ +N + E
Sbjct: 171 APEVYGVAINERRGYGFPVDWWSLGVSLFELLKKRR-PFSVHSNTSLHE 28
>13066
Length = 551
Score = 56.6 bits (135), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 48/183 (26%), Positives = 81/183 (44%), Gaps = 12/183 (6%)
Frame = +3
Query: 231 AEVWLGTWNG----NTKVAIKTL----KPGTMSPESFLEEAQIMKKLKHDKLVQLYAVVS 282
A V GT+N N K+A K + P + F E ++ KL H ++Q+++++
Sbjct: 9 AVVVHGTFNDGYGRNIKLACKIIDKEKAPVDFVEKFFPRELDLLTKLDHPYIIQIHSILQ 188
Query: 283 EEPI-YIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRS 341
P +I + +G LL +++ E +K Q+ + Y+ + HRDL+
Sbjct: 189 RXPKNFIFMRFAERGDLLTYIQ--EVGFVKEKQAKIWFYQMTTALNYLHSYDVAHRDLKC 362
Query: 342 ANILVGNGLICKIADFGL--ARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIK-SDVW 398
NIL+ + K+ADFG A + E E + + APE + K +D W
Sbjct: 363 ENILLSSHFNVKLADFGFACACITESGEKYMSRTYCGSAAYAAPEIVYGAPYAPKVADAW 542
Query: 399 SFG 401
S G
Sbjct: 543 SLG 551
>07836
Length = 1478
Score = 56.6 bits (135), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 62/217 (28%), Positives = 100/217 (46%), Gaps = 42/217 (19%)
Frame = -1
Query: 286 IYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIE--------RMNYIHR 337
++++T+Y GSL D+L R L ++ +A G+A++ + HR
Sbjct: 1328 LFLITDYHENGSLHDYLL---SRVLDSSEMLALAHSAICGLAHLHIEIFGTRGKPAIAHR 1158
Query: 338 DLRSANILVGNGLICKIADFGLA-RLI-EDNEYTA----RQGAKFPIKWTAPEAALYGRF 391
D++S NILV C IAD GLA R I E NE RQG K ++ APE L
Sbjct: 1157 DIKSKNILVKKNGTCCIADLGLAVRYISESNEVDVAPNPRQGTK---RYMAPE-VLEMLL 990
Query: 392 TIK-------SDVWSFGILLTEL----VTKG-----RVPY-------PGMNNREVLEQVE 428
+K +D+++FG+++ E+ V G +VP+ P + ++ V+
Sbjct: 989 NVKNFDAFKQADMYAFGLVMWEIARCCVIGGVAEEYQVPFYNCLPHDPSFEDVRLVVSVD 810
Query: 429 RGYRMPCP---QDCPI--SLHELMIHCWKKDPEERPT 460
+ R P Q+ PI + ++M CW +P R T
Sbjct: 809 K-VRPDIPLRWQEDPIMKVMVKVMCECWSGNPAARLT 702
>09606
Length = 1300
Score = 55.1 bits (131), Expect = 7e-08, Method: Compositional matrix adjust.
Identities = 52/224 (23%), Positives = 96/224 (42%), Gaps = 23/224 (10%)
Frame = -3
Query: 217 RSLCLEKKLGQGCFAEVWLGTWNGNTK-VAIKTLKPGTMSPESFLEEAQIMKKLKHDKLV 275
+ L ++LG+G + ++ G G VAI ++ PE ++ + H +V
Sbjct: 1115 ENFVLYEELGKGEHSIIYKGRRKGTINFVAIHCIEK-CKRPE-VTNTVRMTHDISHPNVV 942
Query: 276 QLYA-VVSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNY 334
Q + + +++V E GSL D L + L ++ D + G+ YI +
Sbjct: 941 QFHEWYETSNHLWLVVELCTGGSLADIL--AQDHHLPETSIRDFGIHLVTGLHYIHSLGI 768
Query: 335 IHRDLRSANILVGNGLICKIADFGLARLIEDNEYT-----ARQGAKFPIK---------- 379
+ DLR + +L+ + K ADFGL+++ +N A G ++ I+
Sbjct: 767 LFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQWNIQSAEEMMKQVP 588
Query: 380 ------WTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPG 417
+ APE +I SD+W+ G + E+ + G P+ G
Sbjct: 587 TSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFS-GHPPFLG 459
>03240
Length = 1683
Score = 54.7 bits (130), Expect = 8e-08, Method: Compositional matrix adjust.
Identities = 46/161 (28%), Positives = 75/161 (46%), Gaps = 9/161 (5%)
Frame = -3
Query: 223 KKLGQGCFAEVWLGTWNGNTKV-AIKTLKPGTMSPESFLE----EAQIMKKLKHDKLVQL 277
K LG G F EV L N + A+KTL+ + + + E I+ + ++ +V+L
Sbjct: 1273 KTLGVGAFGEVSLCRKNDTGMLYAMKTLRKSDVLKRNQVAHVKAERDILAEADNEWVVKL 1094
Query: 278 YAVVSEEP-IYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIH 336
Y + +Y V +Y+ G L+ L E L P A++ + + RM +IH
Sbjct: 1093 YYSFQDHNYLYFVMDYVPGGDLMGLLIRME--ILDEPLARFYVAELVQAIESVHRMGFIH 920
Query: 337 RDLRSANILVGNGLICKIADFGLA---RLIEDNEYTARQGA 374
RD++ NIL+ K+ DFGL R +++Y R G
Sbjct: 919 RDIKPDNILIDRNGHIKLTDFGLCTGFRWTHNSKYYQRDGT 797
>12672
Length = 773
Score = 53.9 bits (128), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 40/164 (24%), Positives = 74/164 (45%), Gaps = 16/164 (9%)
Frame = +3
Query: 323 AAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPI---K 379
A+G+ Y+ ++HRD+++ANIL+ + K+ DF E Q A I
Sbjct: 21 ASGIQYLNDNGHVHRDIKTANILLDSEYTAKVGDFATVVSAPSGEGKTVQNASVVIGTAA 200
Query: 380 WTAPEAALYGRFTIKSDVWSFGILLTELVT----------KGRVPYPGMNNREVLEQVER 429
+ APE A++ + K D +SFG++L E++T + + M N E E++
Sbjct: 201 YLAPE-AIHFDVSTKLDSYSFGVVLLEVITGLVAQDYSREERTLSSHIMENVEEPEEIHD 377
Query: 430 GYRMPC---PQDCPISLHELMIHCWKKDPEERPTFEYLQSFLED 470
P L+++ + C ++RP + ++ LE+
Sbjct: 378 FVDQSAGTWPDGAVDKLYDISMRCLNLSKKQRPNVKDIRPELEE 509
>13212
Length = 1067
Score = 52.8 bits (125), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 45/167 (26%), Positives = 76/167 (45%), Gaps = 11/167 (6%)
Frame = -1
Query: 321 QVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKF---P 377
++ + ++ R + IHRD+++ N+L+ K+ADFG++ N T ++ F P
Sbjct: 956 EMCMALDFLHRHHVIHRDIKAGNVLLTIDGEVKLADFGVSA---KNTQTQQKRDTFIGTP 786
Query: 378 IKWTAPEAALY-----GRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERG-- 430
W APE L + K+D+WS G+ L E + P M+ VL ++ +
Sbjct: 785 Y-WMAPEVVLCETLKDTPYDFKADIWSLGVTLIEFA-QIEPPNKEMHPMRVLIKIHKSDP 612
Query: 431 YRMPCPQDCPISLHELMIHCWKKDPEERPT-FEYLQSFLEDYFTATE 476
+ P+ + + C KDP RPT E L+ TAT+
Sbjct: 611 PTLEKPKKWTKLFKDFIAKCLVKDPNLRPTAAELLEHPFMKRATATD 471
>04138
Length = 800
Score = 52.4 bits (124), Expect = 4e-07, Method: Compositional matrix adjust.
Identities = 32/93 (34%), Positives = 47/93 (50%), Gaps = 7/93 (7%)
Frame = +1
Query: 328 YIERMNYIHRDLRSANILVGNGLICKIADFGLAR-----LIEDNEYTARQGAKFPIKWTA 382
YI R +HRD+++ANIL+ + K+ADFGLAR L + N YT R W
Sbjct: 58 YIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNR----VVTLWYR 225
Query: 383 PEAALYG--RFTIKSDVWSFGILLTELVTKGRV 413
P L G ++ D W G ++ E+ T+ +
Sbjct: 226 PPELLLGDRNYSTAIDQWGAGCIMAEMWTRNPI 324
>21079
Length = 878
Score = 51.6 bits (122), Expect = 7e-07, Method: Compositional matrix adjust.
Identities = 39/143 (27%), Positives = 69/143 (48%), Gaps = 4/143 (2%)
Frame = +1
Query: 271 HDKLVQLY-AVVSEEPIYIVTEYMNKGSLLD-FLKDGEGRALKLPNLVDMAAQVAAGMAY 328
H KL+ L+ A + + +V E++ G L + ++D L + V Q+ +G+ Y
Sbjct: 1 HPKLLMLWDAFEAPRTMVLVMEFVGAGELFERVIRDD--FVLTERDCVHFVRQICSGVGY 174
Query: 329 IERMNYIHRDLRSANILV--GNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAA 386
+ + +H DL+ N+L N KI DFGLAR + + + Q ++ APE
Sbjct: 175 MHTQSILHLDLKPENVLCVSDNSNQIKIIDFGLARFYKPGD--SLQVLFGTPEFIAPEVV 348
Query: 387 LYGRFTIKSDVWSFGILLTELVT 409
Y +D+WS G++ L++
Sbjct: 349 NYDEINFTTDMWSIGVICYILLS 417
>19094
Length = 898
Score = 48.5 bits (114), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 28/83 (33%), Positives = 41/83 (49%)
Frame = +1
Query: 325 GMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPE 384
G+ Y+ IHRD+++ NIL+ N K+ADFG+A + D P W APE
Sbjct: 94 GL*YLHSRRKIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTP-YWMAPE 270
Query: 385 AALYGRFTIKSDVWSFGILLTEL 407
+ +D+WS GI E+
Sbjct: 271 VIQEIGYDCVADIWSLGITALEM 339
>29243
Length = 1147
Score = 48.5 bits (114), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 32/95 (33%), Positives = 48/95 (50%), Gaps = 4/95 (4%)
Frame = +2
Query: 99 EWYFGKLGRKDAERQLLSFGNPRGTFLIRESETT--KGAYSLSIRDWDDMKGDHVKHYKI 156
WY G + R A++ L + P GTFLIR + +G SLSI+ + V+H K+
Sbjct: 305 NWYVGIMERPVAQKXLDTC--PDGTFLIRVTNNPLRRGELSLSIK-----YANAVRHIKV 463
Query: 157 RKLDNGGYYITTRAQFETLQQLVQHY--SEKADGL 189
+ G +Y+ F+ +Q LV HY +E AD
Sbjct: 464 NRNPQGRFYLADGRYFDNIQSLVDHYENNELADSF 568
>15910
Length = 1361
Score = 47.8 bits (112), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 34/114 (29%), Positives = 57/114 (50%), Gaps = 3/114 (2%)
Frame = +2
Query: 320 AQVAAGMAYIERMNYIHRDLRSANIL---VGNGLICKIADFGLARLIEDNEYTARQGAKF 376
+ + G+ YI +HRDL+ N+L + + K+ADFGL+R+IE E
Sbjct: 485 SDILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLADFGLSRIIEP-EVQMSTVCGT 661
Query: 377 PIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERG 430
P + APE ++T D+WS G++ L+ G P+ N E+ ++ +G
Sbjct: 662 P-GYCAPEVLKGDKYTPSVDMWSVGVIAYILLC-GYEPFFAENEFEMYRKIIKG 817
>30755
Length = 1137
Score = 47.4 bits (111), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 37/142 (26%), Positives = 66/142 (46%), Gaps = 2/142 (1%)
Frame = +2
Query: 319 AAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEY--TARQGAKF 376
A++ + + Y+ I+RDL+ N+L+ K+ADFGL + ED Y T +
Sbjct: 50 GAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCK--EDITYGRTTKTFCGT 223
Query: 377 PIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCP 436
P ++ APE + D W G+++ E++ GR+P+ + +VL + + P
Sbjct: 224 P-EYLAPEVLDDNDYGRAVDWWGTGVVMYEMIC-GRLPFYN-RDHDVLFTLILVEDVKFP 394
Query: 437 QDCPISLHELMIHCWKKDPEER 458
++ L+ KDP R
Sbjct: 395 RNITDEAKSLLSGLLAKDPRNR 460
>26560
Length = 398
Score = 46.2 bits (108), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 32/103 (31%), Positives = 52/103 (50%), Gaps = 1/103 (0%)
Frame = -1
Query: 319 AAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPI 378
AA+V G+ ++ ++RDL+ ANIL+ +I+D GLA A G
Sbjct: 338 AAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGLACDFSKKRPHASVGTH--- 168
Query: 379 KWTAPEAALYGR-FTIKSDVWSFGILLTELVTKGRVPYPGMNN 420
+ APE + G+ + +D +SFG +L +L+ KG P+ N
Sbjct: 167 GYMAPEVLMKGQSYDSSADWFSFGCMLYKLL-KGHSPFRQHNQ 42
>21210
Length = 518
Score = 45.8 bits (107), Expect = 4e-05, Method: Compositional matrix adjust.
Identities = 34/86 (39%), Positives = 47/86 (54%), Gaps = 4/86 (4%)
Frame = +3
Query: 383 PEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPG-MNNREVLEQVERGYRMPC-PQDCP 440
P A+ +G + ++SDVWS GI L EL T GR PY ++ + L+QV RG PC P D
Sbjct: 42 PRASSHG-YDVRSDVWSLGITLMELAT-GRFPYRKWVSIFDQLQQVVRGV-APCLPHDGA 212
Query: 441 IS--LHELMIHCWKKDPEERPTFEYL 464
S + C KD ++RP + L
Sbjct: 213 FSHDFVNFVNKCLTKDEKQRPKYNKL 290
>19761
Length = 473
Score = 45.1 bits (105), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 34/119 (28%), Positives = 54/119 (45%), Gaps = 3/119 (2%)
Frame = -3
Query: 321 QVAAGMAYIERMN--YIHRDLRSANILVGNGLICKIADFGLAR-LIEDNEYTARQGAKFP 377
Q A+ + Y+ +HRDL+ NI V ++ D GLAR L ++ Q
Sbjct: 399 QTASALNYMHTHTPVILHRDLKPQNIYVTEKGDVRLGDLGLARKLTGPADFATSQVGT-- 226
Query: 378 IKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCP 436
I + +PE + KSD+WS G + ++ G+ M +L QV G ++P P
Sbjct: 225 IMYLSPEILSQQPYNSKSDIWSLGCVFYDIT--GKKGSDEMGVMFLLVQVMGGRKLPLP 55
>11185
Length = 473
Score = 44.7 bits (104), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 35/142 (24%), Positives = 61/142 (42%), Gaps = 25/142 (17%)
Frame = +1
Query: 317 DMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYT-----AR 371
D + G+ YI + + DLR + +L+ + K ADFGL+++ +N A
Sbjct: 13 DFGIHLVTGLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAE 192
Query: 372 QGAKFPIK----------------WTAPEAALYGRFTIKSDVWSFGILLTELVTKGRV-- 413
G ++ I+ + APE +I SD+W+ G + E+ + R+
Sbjct: 193 AGDQWNIQSAEEMMKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSGSRLSA 372
Query: 414 -PYPG-MNNREVLEQVERGYRM 433
P P +N E L Q + R+
Sbjct: 373 KPSPEFLNLLESLLQKDSTRRL 438
>14257
Length = 919
Score = 44.3 bits (103), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 28/89 (31%), Positives = 47/89 (52%)
Frame = -3
Query: 98 EEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDWDDMKGDHVKHYKIR 157
EEWY GK+GRK+AE+ L G FL+RE+ + + LS R + +V+H +
Sbjct: 896 EEWYHGKIGRKEAEKLL----ELDGDFLVREASNSAAQFVLSGR-----QNGNVRHLLL- 747
Query: 158 KLDNGGYYITTRAQFETLQQLVQHYSEKA 186
+D G T F+++ L+ ++ + A
Sbjct: 746 -VDPDGIVRTKDFIFDSVSHLINYHRQNA 663
>01106
Length = 878
Score = 43.1 bits (100), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 38/140 (27%), Positives = 69/140 (49%), Gaps = 16/140 (11%)
Frame = +3
Query: 223 KKLGQGCFAEVWLGTWNGNTK--VAIKTLKPGTMSPESFLEEAQIMKKLKHD-------- 272
+KLG G F+ VWL W+ K VA+K +K E+ L+E +++K ++
Sbjct: 336 RKLGWGHFSTVWL-CWDLTCKRFVALKVVKSAQHYTETALDEVKLLKCVRESDVADPARA 512
Query: 273 KLVQLY-----AVVSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMA 327
K VQL + V+ + +V E + +LL + + + + N+ + QV G++
Sbjct: 513 KCVQLLDDFKISGVNGTHVAMVFEVLGY-NLLKLIIRSNYQGIPIHNVKLIIRQVLEGLS 689
Query: 328 YIE-RMNYIHRDLRSANILV 346
Y+ + IH D++ NIL+
Sbjct: 690 YMHAKCRIIHTDIKPENILI 749
>28638
Length = 1458
Score = 42.0 bits (97), Expect = 5e-04, Method: Compositional matrix adjust.
Identities = 34/108 (31%), Positives = 52/108 (48%), Gaps = 4/108 (3%)
Frame = -1
Query: 306 EGRALKLPNLVDMAAQVAAGMAYIE--RMNYIHRDLRSANILVGNG--LICKIADFGLAR 361
EG +L L A Q+ + ++ MN IH DL+ NIL+ N KI DFG +
Sbjct: 852 EGVSLNLTR--KFAQQLCTALLFLATPEMNIIHCDLKPENILLCNPKRSAIKIVDFGSSC 679
Query: 362 LIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVT 409
+ Y Q ++F + +PE L + + D+WS G +L E+ T
Sbjct: 678 QLGQRIYQYIQ-SRF---YRSPEVLLGVPYDLAIDMWSLGCILVEMHT 547
>26711
Length = 405
Score = 41.6 bits (96), Expect = 8e-04, Method: Composition-based stats.
Identities = 31/111 (27%), Positives = 54/111 (48%), Gaps = 3/111 (2%)
Frame = -2
Query: 321 QVAAGMAYIERMNYIHRDLRSANILVGNGLI--CKIADFGLAR-LIEDNEYTARQGAKFP 377
QV + ++ +H DL+ +N+L+ + ++ DFGLAR L E G
Sbjct: 392 QVLDILQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARKLYPPQETFLNHGTP-- 219
Query: 378 IKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVE 428
+T+PEA + SDVW G+L L++ G+ P+ + E L++ +
Sbjct: 218 -GFTSPEALDVKPISTASDVWGVGVLAYILLS-GQSPFQADSATESLKKTQ 72
>12786
Length = 460
Score = 41.2 bits (95), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 27/107 (25%), Positives = 51/107 (47%), Gaps = 21/107 (19%)
Frame = -3
Query: 335 IHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPI-KWTAPEAALYG---- 389
IH DL+ AN ++ G + K+ DFG+A ++ ++ + + ++ + +PEA +
Sbjct: 344 IHSDLKPANFMLVAGNL-KLIDFGIANTLQQDKTSVLKDSRVGTPSYMSPEAIMAACDDS 168
Query: 390 ----------------RFTIKSDVWSFGILLTELVTKGRVPYPGMNN 420
+ ++SDVWS G +L +V GR P+ + N
Sbjct: 167 ADDSMEEDGHRTKPKYKVGVRSDVWSLGCILYNMVY-GRTPFQHIKN 30
>37602
Length = 804
Score = 40.4 bits (93), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 23/77 (29%), Positives = 37/77 (48%)
Frame = -1
Query: 281 VSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLR 340
+ E ++I EY GS+ D L P + + + G+ Y+ R +HRD++
Sbjct: 309 LRREKLWIAMEYCGGGSMQDIYH--VTGPLTEPQIAFVCRETLKGLHYLHRRGKMHRDIK 136
Query: 341 SANILVGNGLICKIADF 357
ANIL+ K+ADF
Sbjct: 135 GANILLTEEGDVKLADF 85
>18481
Length = 437
Score = 39.7 bits (91), Expect = 0.003, Method: Composition-based stats.
Identities = 21/65 (32%), Positives = 37/65 (56%), Gaps = 3/65 (4%)
Frame = -1
Query: 308 RALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICK---IADFGLARLIE 364
R L ++ ++ Q+ + + +I + +IHRDL+ N L+G G C I DFGL++ +
Sbjct: 212 RRFTLKTILMVSDQLLSRLEFIHQKCFIHRDLKPDNFLMGLGRHCHRLYIIDFGLSKRYK 33
Query: 365 DNEYT 369
D + T
Sbjct: 32 DTQGT 18
>32000
Length = 644
Score = 39.7 bits (91), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 35/112 (31%), Positives = 54/112 (48%), Gaps = 3/112 (2%)
Frame = -1
Query: 353 KIADFGLARL--IEDNEYTARQGAKFPIKWTAPEAALYGRF-TIKSDVWSFGILLTELVT 409
KIADFGLAR+ + YT + + APE L RF ++ D+WS G + E++T
Sbjct: 569 KIADFGLARVFGLPVRTYTHEVIT---LWYRAPEILLGCRFYSVPVDIWSLGCIFVEMMT 399
Query: 410 KGRVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKKDPEERPTF 461
+ R +PG + + L ++ R P + P K P+ +PTF
Sbjct: 398 R-RALFPGDSEIDQLYRIFRTLGTPDEKVWPGV---------SKLPDYKPTF 273
>32264
Length = 287
Score = 39.7 bits (91), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 18/44 (40%), Positives = 29/44 (65%)
Frame = +1
Query: 427 VERGYRMPCPQDCPISLHELMIHCWKKDPEERPTFEYLQSFLED 470
+E GYR+ P S+++LM+ CW+ PE+RP F+ L + L+D
Sbjct: 1 IEDGYRLQQNPQTPDSVYKLMLRCWEYVPEKRPHFKELYTSLKD 132
>16708
Length = 1397
Score = 38.9 bits (89), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 35/149 (23%), Positives = 74/149 (49%), Gaps = 11/149 (7%)
Frame = -1
Query: 225 LGQGCFAEVWLG-TWNGNTKVAIKTLKPGTMSPESFLEEAQIMKKLKHD-KLVQLY-AVV 281
LG+G F +V+ + + K A+KT ++ L+E + + +++ L Q++ A V
Sbjct: 1379 LGKGVFGKVYEARLLSTHEKAALKT----SILCHHSLDEVEALGRIEGGFYLAQMFGAWV 1212
Query: 282 SEEP---IYIVTEYMNKGSLLDFLKDGEGRALKL----PNLVD-MAAQVAAGMAYIERMN 333
+ P + I+ + G L + + + + + P +V +A Q + +I +
Sbjct: 1211 TCLPFPKMNILLHFYEMGPLCNVYAHYKNKEMPIRWSNPAMVCCIAGQXVCALEHIHELG 1032
Query: 334 YIHRDLRSANILVGNGLICKIADFGLARL 362
+H D+++ N+LV CK+ D+G+A+L
Sbjct: 1031 VVHMDVKADNVLVDAHGNCKLTDYGIAQL 945
>35671
Length = 567
Score = 38.5 bits (88), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 15/47 (31%), Positives = 28/47 (59%)
Frame = -3
Query: 428 ERGYRMPCPQDCPISLHELMIHCWKKDPEERPTFEYLQSFLEDYFTA 474
++G R+ P C +++M+ CW + EERPTF+ L +E+ + +
Sbjct: 565 QKGNRLAKPISCTDEAYKVMLQCWTESREERPTFKKLVPVMENLYRS 425
>00394
Length = 548
Score = 37.7 bits (86), Expect = 0.009, Method: Compositional matrix adjust.
Identities = 29/98 (29%), Positives = 50/98 (51%), Gaps = 11/98 (11%)
Frame = -2
Query: 217 RSLCLEKKLGQGCFAEVWLGTWNGNTKVAI-----KTLKPGTMSPESFLEEAQIMKKLKH 271
R L +K++G+G F V+ G + VA+ + K + F EEA+++K+L+H
Sbjct: 298 RFLKFDKEIGRGSFKTVYKGL-DTELGVAVAWCELQDKKWNKAERQRFKEEAEMLKELQH 122
Query: 272 DKLVQLYAVVSE------EPIYIVTEYMNKGSLLDFLK 303
+V+ + E + I +VTE M G+L +LK
Sbjct: 121 PNIVRFFDYWEEHNHRNRKVIILVTELMTSGTLKTYLK 8
>27405
Length = 532
Score = 37.7 bits (86), Expect = 0.010, Method: Compositional matrix adjust.
Identities = 32/121 (26%), Positives = 52/121 (42%)
Frame = -3
Query: 278 YAVVSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHR 337
YA + E + + + MN G L L + + AA+V G+ ++ ++R
Sbjct: 353 YAFQTPEKLCFILDLMNGGDLHYHLS--QHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYR 180
Query: 338 DLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDV 397
DL+ ANIL+ +I+D GLA + A G + APE + G+ S
Sbjct: 179 DLKPANILLDENGHVRISDLGLACDFSKKKPHASVGTH---GYMAPEVLMKGQAYDSSAD 9
Query: 398 W 398
W
Sbjct: 8 W 6
>38046
Length = 446
Score = 36.6 bits (83), Expect = 0.020, Method: Composition-based stats.
Identities = 15/26 (57%), Positives = 20/26 (76%)
Frame = -1
Query: 322 VAAGMAYIERMNYIHRDLRSANILVG 347
+A MAY+E+ N+IHR+L NILVG
Sbjct: 98 IADAMAYMEKENFIHRNLGDRNILVG 21
>31789
Length = 676
Score = 36.2 bits (82), Expect = 0.031, Method: Compositional matrix adjust.
Identities = 32/121 (26%), Positives = 58/121 (47%), Gaps = 11/121 (9%)
Frame = +2
Query: 217 RSLCLEKKLGQGCFAEVWLGTWNGNTKVAI-----KTLKPGTMSPESFLEEAQIMKKLKH 271
R L + ++G+G F V+ G + VA+ + K + F EEA+++K+L+H
Sbjct: 320 RFLKFDVEIGRGSFKTVYKGL-DTELGVAVAWCELQDKKWNKTERQRFKEEAEMLKELQH 496
Query: 272 DKLVQLYAVVSE------EPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAG 325
+V+ + E + I +VTE M G+L +LK + + L L + Q+ G
Sbjct: 497 PNIVRFFDYWEEHNHRNRKVIILVTELMTSGTLKTYLK--RFKKINLKVLKNWCRQILKG 670
Query: 326 M 326
+
Sbjct: 671 L 673
>21433
Length = 590
Score = 35.8 bits (81), Expect = 0.038, Method: Compositional matrix adjust.
Identities = 25/89 (28%), Positives = 40/89 (44%)
Frame = +2
Query: 321 QVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKW 380
Q+++ + Y IHRD++ N+L+G KIADFG + + T G + +
Sbjct: 191 QLSSALEYCHYRKVIHRDIKPENLLLGLKGDLKIADFGWSVHAPSSRRTTMCGT---LDY 361
Query: 381 TAPEAALYGRFTIKSDVWSFGILLTELVT 409
PE D+WS G+L E +
Sbjct: 362 LPPEMVEGKTHDENVDLWSLGVLCYEFLV 448
>11228
Length = 2155
Score = 35.8 bits (81), Expect = 0.038, Method: Compositional matrix adjust.
Identities = 18/40 (45%), Positives = 25/40 (62%)
Frame = -1
Query: 100 WYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLS 139
WY G+LGR AE L G++L+RESE+ G++ LS
Sbjct: 1972 WYHGRLGRAGAEELLRD--QDAGSYLVRESESKLGSFVLS 1859
Score = 31.6 bits (70), Expect = 0.67, Method: Compositional matrix adjust.
Identities = 26/92 (28%), Positives = 45/92 (48%), Gaps = 1/92 (1%)
Frame = -2
Query: 92 DYEARTEEWYFGK-LGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDWDDMKGDH 150
DYE YF L +++A +L+ G G+FL+R+SE G YSL D
Sbjct: 1491 DYEPVESLPYFHSCLSKEEAVEKLMLAGE--GSFLVRQSENYPGDYSLFFLCEKD----- 1333
Query: 151 VKHYKIRKLDNGGYYITTRAQFETLQQLVQHY 182
V+ ++I + G ++ F++L +++ Y
Sbjct: 1332 VRRFRIER--RGNQFLVGGRLFDSLDGVIKRY 1243
>01392
Length = 1806
Score = 35.8 bits (81), Expect = 0.042, Method: Compositional matrix adjust.
Identities = 32/109 (29%), Positives = 51/109 (46%), Gaps = 12/109 (11%)
Frame = -1
Query: 321 QVAAGMAYIERMNYIHRDLRSANIL---VGNGLICKIADFGLARLIE-DNEYTARQGAKF 376
+A + ++ HRDL+ NIL + + + KI DF LA I D + T
Sbjct: 1767 HIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGISCDGDGTKTPELLT 1588
Query: 377 PI---KWTAPEA--ALYG---RFTIKSDVWSFGILLTELVTKGRVPYPG 417
P+ ++ APE A G + + D+WS GI+L ++ G P+ G
Sbjct: 1587 PVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILYIMLC-GYPPFYG 1444
>18881
Length = 762
Score = 35.4 bits (80), Expect = 0.056, Method: Compositional matrix adjust.
Identities = 22/67 (32%), Positives = 35/67 (52%), Gaps = 2/67 (2%)
Frame = -3
Query: 120 PRGTFLIRESETTKGAYSLSIRDWDDMK--GDHVKHYKIRKLDNGGYYITTRAQFETLQQ 177
P GTFLIR + T S R+ + V+H K+ + G +Y+ F+++QQ
Sbjct: 748 PDGTFLIRVTNT-------SARESCPQY*YANAVRHIKVNRNPQGRFYLADGHYFDSVQQ 590
Query: 178 LVQHYSE 184
LV+HY +
Sbjct: 589 LVEHYEK 569
>07933
Length = 728
Score = 35.0 bits (79), Expect = 0.062, Method: Compositional matrix adjust.
Identities = 13/30 (43%), Positives = 18/30 (60%)
Frame = +3
Query: 436 PQDCPISLHELMIHCWKKDPEERPTFEYLQ 465
P CP L+ +M+ CW +P RPTF L+
Sbjct: 3 PNYCPNLLYNIMMQCWSAEPSARPTFHKLE 92
>37260
Length = 401
Score = 34.3 bits (77), Expect = 0.13, Method: Composition-based stats.
Identities = 17/56 (30%), Positives = 30/56 (53%)
Frame = -1
Query: 100 WYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDWDDMKGDHVKHYK 155
WY+G L ++AE +L+ G+FL+R+S SLS + + ++H+K
Sbjct: 182 WYWGPLSYEEAESKLMD--KRDGSFLVRDSSNENYILSLSFKSMGHVHHTRIEHHK 21
>02638
Length = 1490
Score = 33.9 bits (76), Expect = 0.14, Method: Compositional matrix adjust.
Identities = 25/103 (24%), Positives = 49/103 (47%), Gaps = 7/103 (6%)
Frame = +1
Query: 378 IKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRM---- 433
I + APE + DVWS G ++ E+ T R P+ N+ ++ + +++
Sbjct: 28 IAFMAPEVLRGESYGRACDVWSVGCVMIEMCT-CRPPW---NSHDISNHLALIFKIASSV 195
Query: 434 ---PCPQDCPISLHELMIHCWKKDPEERPTFEYLQSFLEDYFT 473
P P++ + +LM+ C ++D + RP+ + L + FT
Sbjct: 196 DPPPIPENMSPPVRDLMLRCLEQDSDFRPSAKDL--LMHPLFT 318
>29360
Length = 363
Score = 33.5 bits (75), Expect = 0.18, Method: Composition-based stats.
Identities = 28/116 (24%), Positives = 50/116 (43%), Gaps = 7/116 (6%)
Frame = +3
Query: 238 WNGNTK--VAIKTLKPGTMSPESFLEEAQIMKKLKHD-----KLVQLYAVVSEEPIYIVT 290
W T VAIK LK E I+++L + V+ + + +
Sbjct: 12 WKKGTSEIVAIKILKNHPSYARQGQIEVSILQRLSQESADDYNFVRAFECFQHKNHTCLV 191
Query: 291 EYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILV 346
M + +L DFLK + + L L + + QV + ++++ IH DL+ NI++
Sbjct: 192 FEMLEQNLYDFLKQNKFQPLPLKYIRPITQQVLTALRKLKQLGLIHADLKPENIML 359
>06462
Length = 1511
Score = 33.5 bits (75), Expect = 0.21, Method: Compositional matrix adjust.
Identities = 24/85 (28%), Positives = 38/85 (44%)
Frame = +1
Query: 98 EEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDWDDMKGDHVKHYKIR 157
E WY GK+ R++AE+ L G FL+RES + LS + H + +
Sbjct: 1090 ELWYHGKMSRREAEKLL----GKDGDFLVRESGHNXSQFVLSGK-------HHGQFIHLL 1236
Query: 158 KLDNGGYYITTRAQFETLQQLVQHY 182
+D G T F+ + LV ++
Sbjct: 1237 LVDPDGIVRTKDYIFDNISHLVSYH 1311
>24983
Length = 433
Score = 32.3 bits (72), Expect = 0.46, Method: Composition-based stats.
Identities = 17/53 (32%), Positives = 25/53 (47%), Gaps = 6/53 (11%)
Frame = +2
Query: 189 LCFNLTVIASSCTPQTSGLAKDAWEVA------RRSLCLEKKLGQGCFAEVWL 235
+C ++ ASS +P S ++ W V RRS C+ + LG E WL
Sbjct: 203 VCLSVMTTASSMSPNLSKYSRKLWSVV**GXPPRRSWCM*ELLGASDVCERWL 361
>17516
Length = 453
Score = 31.6 bits (70), Expect = 0.78, Method: Compositional matrix adjust.
Identities = 28/101 (27%), Positives = 47/101 (46%), Gaps = 6/101 (5%)
Frame = -3
Query: 382 APEAALY-GRFTIKSDVWSFGILLTELVTKGRVPYPGMNNR---EVLEQVERGYRMPCPQ 437
APE L G++ +K+DV+S I+L EL G+ +++ + + V+ G R
Sbjct: 415 APEVLLQKGQYDMKADVYSLAIILWEL-WYGQDAADHISSHLFGRLEDAVQAGLRPSVTM 239
Query: 438 DC--PISLHELMIHCWKKDPEERPTFEYLQSFLEDYFTATE 476
C P +L+ W+ +RPT F ED+ T+
Sbjct: 238 TCKPPDDWLKLLQSGWEFHASKRPTSRDAAEFFEDFLERTK 116
>18401
Length = 463
Score = 31.2 bits (69), Expect = 1.1, Method: Compositional matrix adjust.
Identities = 18/50 (36%), Positives = 27/50 (54%)
Frame = -3
Query: 380 WTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVER 429
+ APE L ++ DVWS G ++ EL T G + +N+E L +ER
Sbjct: 434 YRAPEVILELGWSHPCDVWSVGCIMFELYT-GYTLFQTHDNKEHLAMMER 288
>23319
Length = 2235
Score = 30.8 bits (68), Expect = 1.2, Method: Compositional matrix adjust.
Identities = 12/45 (26%), Positives = 24/45 (53%)
Frame = +3
Query: 383 PEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQV 427
P+ ++ D+WS G + EL GR +PG ++ + L+++
Sbjct: 3 PDVYXAKMYSTSIDMWSAGCIFAELANAGRPLFPGNDDDDQLKRI 137
>27287
Length = 514
Score = 30.8 bits (68), Expect = 1.3, Method: Compositional matrix adjust.
Identities = 11/30 (36%), Positives = 19/30 (63%)
Frame = -2
Query: 446 LMIHCWKKDPEERPTFEYLQSFLEDYFTAT 475
+M CW++DP +RP+F L L+ T++
Sbjct: 474 IMHSCWQEDPNDRPSFSRLVQELDKMLTSS 385
>29590
Length = 320
Score = 30.4 bits (67), Expect = 1.9, Method: Composition-based stats.
Identities = 13/43 (30%), Positives = 26/43 (60%)
Frame = +3
Query: 380 WTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNRE 422
+ APE Y +I++D+WS G+L ++T P+ G+ +++
Sbjct: 72 YVAPEVLDYEPLSIQTDMWSLGVLSYVMLTACS-PFVGITSKK 197
>36481
Length = 806
Score = 30.0 bits (66), Expect = 2.4, Method: Compositional matrix adjust.
Identities = 26/108 (24%), Positives = 48/108 (44%), Gaps = 6/108 (5%)
Frame = +2
Query: 244 VAIKTLKPGTMSPESFLEEAQIMKKLK----HDK--LVQLYAVVSEEPIYIVTEYMNKGS 297
+A+K +K E+ E +++KL+ H K VQ+ ++ +M S
Sbjct: 446 IALKIIKNVDKYREAAKLEINVLEKLREKDPHAKHMCVQMLDWFDYHGHVCISFHMLGLS 625
Query: 298 LLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANIL 345
+ DFLKD A + + ++ Q+ + ++ H DL+ NIL
Sbjct: 626 VFDFLKDNSYGAYPIEQVRHISYQLCYAVNFLHENQLTHTDLKPENIL 769
>27562
Length = 399
Score = 29.3 bits (64), Expect = 3.5, Method: Composition-based stats.
Identities = 18/54 (33%), Positives = 26/54 (48%), Gaps = 3/54 (5%)
Frame = -1
Query: 421 REVLEQVERGYRMPCPQDCPISLHELMIH-CWKKDPEERPT--FEYLQSFLEDY 471
R + Q+ R P+ C SL E++ WKKDP ER E L F++ +
Sbjct: 222 RVLWTQMRRRGTQIQPRPCSSSLFEIL*ETAWKKDPSERTENDIEILMDFMQHF 61
>18663
Length = 600
Score = 28.5 bits (62), Expect = 6.4, Method: Compositional matrix adjust.
Identities = 20/66 (30%), Positives = 30/66 (45%), Gaps = 10/66 (15%)
Frame = +2
Query: 379 KWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPY--------PGMNNREVLEQV--E 428
+ APE + D W+ G+LL E++ GR P+ P N + L QV E
Sbjct: 23 NYIAPEILRGEDYGFSVDWWALGVLLYEMLA-GRSPFDIAGASENPDQNTEDYLFQVILE 199
Query: 429 RGYRMP 434
+ R+P
Sbjct: 200 KTIRIP 217
>15741
Length = 402
Score = 28.5 bits (62), Expect = 7.1, Method: Composition-based stats.
Identities = 11/32 (34%), Positives = 18/32 (56%)
Frame = -3
Query: 314 NLVDMAAQVAAGMAYIERMNYIHRDLRSANIL 345
+ A VA GMA++ +HRD+ + N+L
Sbjct: 97 DFFSFALHVARGMAHVANNKIVHRDVAARNVL 2
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000357671 | hsapiens_gene_ensembl | Proto-oncogene
tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn) (Protooncogene
Syn) (SLK). [Source:Uniprot/SWISSPROT;Acc:P06241]
(534 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
21808 318 8e-88
06405 299 2e-81
11780 192 5e-69
09007 153 2e-37
04852 147 8e-36
17300 122 2e-33
20640 125 5e-29
07291 122 3e-28
14116 121 6e-28
08294 104 9e-23
07940 102 5e-22
18996 98 7e-21
22005 82 3e-20
01718 94 1e-19
17637 93 3e-19
13592 90 2e-18
14477 89 5e-18
13305 80 3e-15
19301 79 6e-15
01756 77 1e-14
00715 77 2e-14
12721 71 9e-13
17253 70 3e-12
01060 69 4e-12
01707 69 7e-12
18921 67 1e-11
29581 66 4e-11
14126 64 1e-10
00300 64 2e-10
25550 64 2e-10
18484 63 3e-10
14420 62 7e-10
27546 61 1e-09
04591 61 1e-09
00392 59 6e-09
01966 58 7e-09
11228 58 8e-09
31885 57 2e-08
07836 57 2e-08
13066 57 2e-08
09606 55 8e-08
03240 55 1e-07
12672 54 2e-07
13212 53 3e-07
04138 52 4e-07
29243 52 7e-07
21079 52 8e-07
12324 49 5e-06
19094 49 7e-06
15910 48 1e-05
30755 47 1e-05
21210 46 5e-05
19761 45 7e-05
29687 45 8e-05
26560 45 1e-04
11185 44 1e-04
14257 44 1e-04
01106 44 2e-04
28638 42 5e-04
28095 42 8e-04
12786 41 0.001
26711 41 0.001
05206 41 0.001
37602 41 0.002
01494 40 0.002
18481 40 0.003
32000 40 0.003
32264 40 0.003
16708 39 0.004
35671 39 0.007
00394 38 0.011
16716 38 0.013
27405 37 0.014
17286 37 0.015
30740 37 0.017
38046 37 0.023
06462 36 0.032
31789 36 0.033
21433 36 0.047
01392 36 0.048
18881 35 0.058
07933 35 0.070
13664 35 0.071
02638 34 0.14
37260 34 0.18
29360 34 0.19
24983 32 0.58
17516 31 1.1
18401 31 1.3
13641 31 1.3
23319 31 1.5
27287 31 1.5
29590 30 2.4
36481 30 2.8
27562 29 4.2
18663 28 7.5
15741 28 8.0
>21808
Length = 1011
Score = 318 bits (814), Expect(2) = 8e-88, Method: Compositional matrix adjust.
Identities = 152/225 (67%), Positives = 180/225 (80%), Gaps = 1/225 (0%)
Frame = +1
Query: 285 GTWNGNTKVAIKTLKPGTMSPESFLEEAQIMKKLKHDKLVQLYAVVSEE-PIYIVTEYMN 343
G WN T VAIKTLK GTM P+ FL EAQIMKKL+H KL+QLYAV +++ PI+I+TE M
Sbjct: 4 GLWNNTTPVAIKTLKSGTMDPKDFLAEAQIMKKLRHPKLIQLYAVCTQDDPIFIITELMK 183
Query: 344 KGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKI 403
GSLL+FL+ G+GR LKLP L+D+ AQ+A GMAY+E NYIHRDL + NILV + KI
Sbjct: 184 NGSLLEFLQ-GKGRVLKLPALIDIGAQIACGMAYLESQNYIHRDLAARNILVSDNNTVKI 360
Query: 404 ADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVP 463
ADFGLAR+I+++EY AR GA+FPIKWTAPEAA Y RFTIKSDVWSFGILLTE VT GRVP
Sbjct: 361 ADFGLARVIKEDEYEARVGARFPIKWTAPEAANYNRFTIKSDVWSFGILLTETVTYGRVP 540
Query: 464 YPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKKDPEERP 508
YPGM N EVL QVE GYRMPCP CP L+++M+ CW+K+ ERP
Sbjct: 541 YPGMTNAEVLHQVEHGYRMPCPPGCPKPLYDIMLECWRKEEMERP 675
Score = 25.0 bits (53), Expect(2) = 8e-88, Method: Compositional matrix adjust.
Identities = 11/22 (50%), Positives = 14/22 (63%)
Frame = +2
Query: 508 PTFEYLQSFLEDYFTATEPQYQ 529
PTFE LQ LE++FT Y+
Sbjct: 674 PTFETLQWKLEEFFTMDSKDYR 739
>06405
Length = 1965
Score = 299 bits (766), Expect = 2e-81, Method: Compositional matrix adjust.
Identities = 160/350 (45%), Positives = 221/350 (63%), Gaps = 5/350 (1%)
Frame = +1
Query: 177 ESETTKGAYSLSIRDWDDMKGDHVKHYKIRKLDNGGYYITTRAQFETLQQLVQHYSEKAD 236
ESE++ G S+S+R +G V HY+I + D+G ++T +F TL +LV H+S AD
Sbjct: 1 ESESSPGQRSISVR----FEG-RVYHYRITE-DDGKVFVTQEHRFNTLAELVHHHSIHAD 162
Query: 237 GLCFNLTVIASS-CTPQTSGLAK--DAWEVARRSLCLEKKLGQGCFAEVWLGTWNG-NTK 292
GL L A P G++ D WE+ R + ++ +LG G + +V+ W N
Sbjct: 163 GLVTTLLYPAPKRQKPTVFGVSPEPDRWEIERTEIAMKHRLGGGQYGDVYEAMWKRYNKI 342
Query: 293 VAIKTLKPGTMSPESFLEEAQIMKKLKHDKLVQLYAVVSEEP-IYIVTEYMNKGSLLDFL 351
VA+KTLK TM+ FLEEA IMK++KH LVQL V + EP YIVTE+M G+LLD+L
Sbjct: 343 VAVKTLKEDTMALNDFLEEAAIMKEMKHPNLVQLLGVCTREPPFYIVTEFMPHGNLLDYL 522
Query: 352 KDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARL 411
+ L+ MA Q+A+GMAY+E N+IHRDL + N LV + + K+ADFGLARL
Sbjct: 523 RSSTREENGPTALMYMATQIASGMAYLETKNFIHRDLAARNCLVADSNMVKVADFGLARL 702
Query: 412 IEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNRE 471
++D+ YTA GAKFPIKWTAPE + RF+ +SD+W+FG+LL EL T G PYPG+ E
Sbjct: 703 MKDDTYTAHIGAKFPIKWTAPEGLAFNRFSTRSDIWAFGVLLWELATYGMSPYPGVELTE 882
Query: 472 VLEQVERGYRMPCPQDCPISLHELMIHCWKKDPEERPTFEYLQSFLEDYF 521
V +ERGYRM P P ++ LM+ CW+ DP++RPTF+ + LE+ F
Sbjct: 883 VYHLLERGYRMERPPGTPADVYILMLKCWQWDPKDRPTFKEIHFLLENMF 1032
>11780
Length = 1713
Score = 192 bits (489), Expect(2) = 5e-69, Method: Compositional matrix adjust.
Identities = 122/341 (35%), Positives = 178/341 (52%), Gaps = 9/341 (2%)
Frame = +3
Query: 103 FHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYVAP--VDSIQAEEWYFGKLGRKDAE 160
F KG+ I ++ W + G G IP+NYV P V ++ A W+ GK+ R+ AE
Sbjct: 111 FQKGDLLVIRRATSDRMWYKACDSNGREGMIPANYVQPRKVVTLHAMPWFHGKITRQQAE 290
Query: 161 RQLLSFGNPR--GTFLIRESETTKGAYSLSIRDWDDMKGDHVKHYKIRKLDNGGYYITTR 218
L PR G FLIRES G Y+L + V+HY+I +N I
Sbjct: 291 ELL----KPREDGLFLIRESSNYPGDYTLCV-----CHLGKVEHYRILYRENQ-LTIDEE 440
Query: 219 AQFETLQQLVQHYSEKADGLCFNLTVIASS-----CTPQTSGLAKDAWEVARRSLCLEKK 273
F L +LV+HY ADGLC LT + T W +A + L + +
Sbjct: 441 GFFRNLDELVKHYLADADGLCTQLTRPVTKQGGNFGTVSLQEFKSGGWVIAXQDLEIGEA 620
Query: 274 LGQGCFAEVWLGTWNGNTKVAIKTLKPGTMSPESFLEEAQIMKKLKHDKLVQLYAVVSEE 333
+G+G F +V+ G + G VAIK LK +SFL+EA +M L+HD LV+L VV E
Sbjct: 621 IGKGDFGDVYKGMYRGQP-VAIKQLKDKDRGEQSFLQEASVMTSLRHDNLVRLIGVVLGE 797
Query: 334 PIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANI 393
I++VTE+M KG+L+++L+ + + ++ A A M Y+E +HRDL + N+
Sbjct: 798 TIFLVTEFMGKGNLVEYLRSRGRSVITKKDQINFATDTCAAMEYLESKRLVHRDLAARNV 977
Query: 394 LVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEA 434
LV + K++DFGLA+ + ++ + KFPIKWTAPEA
Sbjct: 978 LVHDDGKAKVSDFGLAKFGDFSQTS----VKFPIKWTAPEA 1088
Score = 87.0 bits (214), Expect(2) = 5e-69, Method: Compositional matrix adjust.
Identities = 41/86 (47%), Positives = 57/86 (66%)
Frame = +1
Query: 439 RFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIH 498
+FT KSD+WSFGILL E+ + GRVPYP + +V+ VERGYRM P+ CP ++ +M
Sbjct: 1102 KFTSKSDMWSFGILLWEIYSFGRVPYPRIPLTDVVMHVERGYRMEAPEGCPPEIYSIMKQ 1281
Query: 499 CWKKDPEERPTFEYLQSFLEDYFTAT 524
W+ DP ERPTF+ + + L + T
Sbjct: 1282 AWELDPNERPTFKSVLARLNNQRAVT 1359
>09007
Length = 1440
Score = 153 bits (387), Expect = 2e-37, Method: Compositional matrix adjust.
Identities = 97/283 (34%), Positives = 151/283 (53%), Gaps = 15/283 (5%)
Frame = -1
Query: 263 VARRSLCLEKKLGQGCFAEVWLGTWNGNT----KVAIKTLKPGTMSP--ESFLEEAQIMK 316
+++ + L K LGQG F V W + +VA+K L + + FL+E IM+
Sbjct: 888 ISKDCVALSKSLGQGHFGTVRQAIWTAESGEKVQVAVKCLSKDKIHKDGQEFLKETAIMQ 709
Query: 317 KLKHDKLVQLYAVVSEE--PIYIVTEYMNKGSLLDFLKDGEGRA-LKLPNLVDMAAQVAA 373
L H+ +V++Y VV + I +VTE SLL+ +K+ R +P L D + QV
Sbjct: 708 MLDHENIVRVYGVVMDNGADIMLVTELAPMRSLLECVKEVSARVDFSVPRLCDFSQQVCD 529
Query: 374 GMAYIERMNYIHRDLRSANILVGNGLICKIADFGLA-RLIEDNEYTARQGA---KFPIKW 429
GM+Y+E +HRDL + NIL+ + KI+D G++ L EY Q + + W
Sbjct: 528 GMSYLESKRLVHRDLAARNILLFSKSKVKISDVGVSGALGAGKEYYQSQQTIHLQNAVAW 349
Query: 430 TAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVE--RGYRMPCPQD 487
APE+ F+ SDVW+FG+LL E T G P+ G+N ++++E V+ + R+ P
Sbjct: 348 CAPESFRNLCFSSASDVWAFGVLLWEFFTHGFQPWAGLNGQQIMEAVDAPQSQRLEQPDL 169
Query: 488 CPISLHELMIHCWKKDPEERPTFEYLQSFLEDYFTATEPQYQP 530
CP + +M+ CW+++P+ RPTF L FL T PQ +P
Sbjct: 168 CPKEYYAVMLKCWEQEPQRRPTFSQL--FL------TLPQIRP 64
>04852
Length = 1462
Score = 147 bits (372), Expect = 8e-36, Method: Compositional matrix adjust.
Identities = 87/259 (33%), Positives = 136/259 (52%), Gaps = 31/259 (11%)
Frame = +1
Query: 291 TKVAIKTLKPGTMSPE--SFLEEAQIMKKLK----HDKLVQLYAVVSEE-PIYIVTEYMN 343
+ VA+K L+ + E F++E Q+MK +K H +V ++ P++++ E+
Sbjct: 22 STVAVKMLRDIVTAVEEQDFVQELQVMKAVKKMGSHINIVNFLGCCTQGGPLWVIVEFAK 201
Query: 344 KGSLLDFL---KDG--------------------EGRALKLPNLVDMAAQVAAGMAYIER 380
G+L DFL +DG G ++ NL+ A Q+A GM ++
Sbjct: 202 NGNLRDFLESCRDGINGYGKFVSPQDPGWYTKTPGGHVIRRKNLLSYAFQIARGMEFLAS 381
Query: 381 MNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRF 440
IHRDL + N+LV + KIADFGL+R + Y R G + P+KW APEA R+
Sbjct: 382 RKCIHRDLAARNVLVTEEHVLKIADFGLSR--TGDYYKKRSGGRLPVKWMAPEALFDMRY 555
Query: 441 TIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQ-VERGYRMPCPQDCPISLHELMIHC 499
T KSDVWSFG++L E+ + G +PY + N E+ + ++ YRMP P+ +L+ +M C
Sbjct: 556 TTKSDVWSFGVVLWEIFSLGGMPYASIPNEELYSKLLDDAYRMPRPELASGNLYAIMERC 735
Query: 500 WKKDPEERPTFEYLQSFLE 518
W P +RP F L ++
Sbjct: 736 WLNRPSDRPEFSQLVGHID 792
>17300
Length = 480
Score = 122 bits (307), Expect(2) = 2e-33, Method: Compositional matrix adjust.
Identities = 56/117 (47%), Positives = 83/117 (70%), Gaps = 4/117 (3%)
Frame = +1
Query: 371 VAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDN----EYTARQGAKFP 426
+++GM + M Y+HRDL + NILV L+CK+ADFGL+R IE + YT + G K P
Sbjct: 1 ISSGMGXLADMGYVHRDLAARNILVNEILVCKVADFGLSREIESDTTEGAYTTK-GGKIP 177
Query: 427 IKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMP 483
++WTAPEA Y +FT SDVWSFG+++ E+++ G PY +N++V++ VE+GYR+P
Sbjct: 178 VRWTAPEAIAYRKFTSASDVWSFGVVMWEVMSYGERPYWNWSNQDVIKAVEKGYRLP 348
Score = 38.1 bits (87), Expect(2) = 2e-33, Method: Composition-based stats.
Identities = 16/43 (37%), Positives = 23/43 (53%), Gaps = 1/43 (2%)
Frame = +2
Query: 484 CPQ-DCPISLHELMIHCWKKDPEERPTFEYLQSFLEDYFTATE 525
CP DCP +LH+LM+ W+K+ RP + L+ A E
Sbjct: 344 CPSMDCPEALHQLMLDAWQKERSHRPKMSMVVKTLDKLIRAPE 472
>20640
Length = 1492
Score = 125 bits (313), Expect = 5e-29, Method: Compositional matrix adjust.
Identities = 59/144 (40%), Positives = 86/144 (59%), Gaps = 1/144 (0%)
Frame = +1
Query: 383 YIHRDLRSANILVGNGLICKIADFGLARLIED-NEYTARQGAKFPIKWTAPEAALYGRFT 441
Y+HRDL + N LVG+ L+ KI+DFGLAR + + Y + PI+W EA LY +F+
Sbjct: 7 YVHRDLATRNCLVGHDLVVKISDFGLARSVHSVDYYRGSEHDAIPIRWMPLEAILYNKFS 186
Query: 442 IKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWK 501
+SDVWSFG++L E+ PY G+ + EV+ V+ G + CP+ P ++ELM CW
Sbjct: 187 TQSDVWSFGVVLWEIFAFALQPYYGLTHEEVVRFVKEGKVLACPERTPPPMYELMKQCWH 366
Query: 502 KDPEERPTFEYLQSFLEDYFTATE 525
+ P RP+F L LE+ + E
Sbjct: 367 RRPATRPSFHTLHKTLENMHSKYE 438
>07291
Length = 833
Score = 122 bits (307), Expect = 3e-28, Method: Compositional matrix adjust.
Identities = 60/167 (35%), Positives = 98/167 (58%), Gaps = 2/167 (1%)
Frame = +1
Query: 356 GRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLA-RLIED 414
+ L + L+D Q+A GMAY++ + +HR+L + N +V +++D+G+ L
Sbjct: 31 SKMLTVVQLLDFGRQIADGMAYLQEVKVVHRNLAARNCIVTEDGRLQLSDYGVTGSLFPQ 210
Query: 415 NEYTARQG-AKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVL 473
+ YTA A+ +KW APE F+ KSDVW+FG++L EL+T+G PYP + N +L
Sbjct: 211 SYYTADDSPARDLVKWMAPETIDNFHFSSKSDVWAFGVVLWELLTRGITPYPDVENSSLL 390
Query: 474 EQVERGYRMPCPQDCPISLHELMIHCWKKDPEERPTFEYLQSFLEDY 520
++ G+RM P+ P ++E+M CW + PE+RP F L L+ +
Sbjct: 391 PYLKEGHRMKKPKQSPEPVYEMMTACWNESPEQRPDFAELNDQLKTF 531
>14116
Length = 1017
Score = 121 bits (304), Expect = 6e-28, Method: Compositional matrix adjust.
Identities = 72/216 (33%), Positives = 120/216 (55%), Gaps = 13/216 (6%)
Frame = -1
Query: 263 VARRSLCLEKKLGQGCFAEVWLGTWN-----GNTKVAIKTL---KPGTMSPESFLEEAQI 314
+ R L + +++G+G F V G G+ VA+KTL P + +SFL+EA I
Sbjct: 645 IDREFLTMGEEIGKGNFGCVKRGFLTLPEQKGDILVAVKTLHNNNPREIELQSFLQEALI 466
Query: 315 MKKLKHDKLVQLYAV---VSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQV 371
MK H ++ L + + + P+ +V +M G LL +++D + + + +L+ +
Sbjct: 465 MKDFHHSNVLTLIGICLNLDDMPL-VVLPFMKHGDLLTYIRDDQHQP-TIKDLIMYGVDI 292
Query: 372 AAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQG--AKFPIKW 429
A GM Y+ + ++HRDL + N ++ K+ADFGLAR I + EY + + AK P+KW
Sbjct: 291 ARGMDYLAGLKFVHRDLAARNCMLDEDFHVKVADFGLARDIYEKEYYSSENKKAKLPVKW 112
Query: 430 TAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYP 465
A E+ G + K+DVWS+G++L EL+T+G P
Sbjct: 111 MALESLEKGNYDSKTDVWSYGVVLWELLTRGSDALP 4
>08294
Length = 1849
Score = 104 bits (260), Expect = 9e-23, Method: Compositional matrix adjust.
Identities = 64/207 (30%), Positives = 100/207 (48%), Gaps = 11/207 (5%)
Frame = +2
Query: 322 KLVQLYAVVSE-EPIYIVTEYMNKGSLLDFL-----KDGEGRALKLPNL-----VDMAAQ 370
+V V E EP +++TEY + G L FL +G GR ++P L + M Q
Sbjct: 890 NIVHFMGVCREAEPHFLITEYCDWGDLKQFLLATRNDNGRGRGTRVPALALSQKLGMGQQ 1069
Query: 371 VAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWT 430
VAAGM + +H DL + N+L+ + + K+A L+ + +EY P++W
Sbjct: 1070 VAAGMEALSNQGLVHGDLAARNVLLTSRMQLKVARPALSGDVYASEYYPLHQRLVPLRWL 1249
Query: 431 APEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPI 490
PE L T DVW+FG+ L E++ +PY M++ EVL ++ D P
Sbjct: 1250 PPEGVLEDSATTCGDVWAFGVFLWEVLQLADLPYRLMSDEEVLRSLQHSQAALDSPDAPP 1429
Query: 491 SLHELMIHCWKKDPEERPTFEYLQSFL 517
+L L+ C + P +RP F + S L
Sbjct: 1430 ALLSLLQRCTAQQPSQRPPFSEICSVL 1510
>07940
Length = 1336
Score = 102 bits (253), Expect = 5e-22, Method: Compositional matrix adjust.
Identities = 79/277 (28%), Positives = 117/277 (42%), Gaps = 70/277 (25%)
Frame = -3
Query: 261 WEVARRSLCLEKKLGQGCFAEVWLGTW------NGNTKVAIKTLKPGTMSPE--SFLEEA 312
WE R L L +LG+G F V G N + VA+K LK E + E
Sbjct: 857 WEFPRERLVLGDRLGEGAFGLVMKGEAMGIFKDNNSVTVAVKMLKEDATDREMMDLIREM 678
Query: 313 QIMKKL-KHDKLVQ----------LYAVVSEEPIYIVTEYMN------------------ 343
++MK + KH ++ LY +V P + +++
Sbjct: 677 EMMKVIGKHKNIINLLGCCTQRGALYVIVEFAPHGNLRDFLKSHRPHGTSYSCIADYEQP 498
Query: 344 -------------------KGSLLDFL-------------KDGEGRALKLPNLVDMAAQV 371
+G+ L F+ + + L +L+ A QV
Sbjct: 497 VITSSSSSFSHPNSASSSAQGTSLGFIPGTSTVSFSTGSHRQDMLKMLTPKDLISYAYQV 318
Query: 372 AAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQ-GAKFPIKWT 430
A GM Y+ IHRDL + N+LV + KIADFGL R ++ +Y + + P+KW
Sbjct: 317 ARGMEYLASKQCIHRDLAARNVLVAEEYVLKIADFGLTRNLQQFDYYRKTTDGRLPVKWM 138
Query: 431 APEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGM 467
APEA ++T KSDVWS+G+LL E+ T G PYP +
Sbjct: 137 APEALFDRKYTSKSDVWSYGVLLWEIFTLGGNPYPSV 27
>18996
Length = 491
Score = 98.2 bits (243), Expect = 7e-21, Method: Compositional matrix adjust.
Identities = 55/136 (40%), Positives = 79/136 (58%), Gaps = 6/136 (4%)
Frame = +2
Query: 384 IHRDLRSANILVGNGLICKIADFGLARLIE-DNEYTARQGAKFPIKWTAPEAALYGRFTI 442
IHRDL + NILV + KI+DFGLA+ D Y PIKW +PEA +F+
Sbjct: 2 IHRDLAARNILVDRSCV-KISDFGLAQFANADGYYYGISQRDIPIKWYSPEAIETCKFSS 178
Query: 443 KSDVWSFGILLTELVTKGRVP--YPG--MNNREVLEQVERGYRMPCPQDCPISLH-ELMI 497
SDVWS+G+ L E+ ++G +P PG + E L ++ +G R+P P+ C ++ ELM
Sbjct: 179 YSDVWSYGVTLFEMFSRGEIPNLLPGHDLTQEEFLNRLRKGERLPKPELCSDFVYSELMR 358
Query: 498 HCWKKDPEERPTFEYL 513
CW + P+ RPTF +
Sbjct: 359 PCWHEMPKSRPTFHQI 406
>22005
Length = 873
Score = 82.4 bits (202), Expect(2) = 3e-20, Method: Compositional matrix adjust.
Identities = 58/194 (29%), Positives = 91/194 (46%), Gaps = 44/194 (22%)
Frame = +1
Query: 308 FLEEAQIMKKLKHDKLVQLYAVVS-EEPIYIVTEYMNKGSLLDFLKDGEGRALKLP---- 362
F EA +M H +V+L V + +P+ ++ E+M+KG L DFL+ LP
Sbjct: 151 FEREASLMADFDHPNIVKLLGVCAIGKPMCLLFEFMSKGDLNDFLRLCSPENYNLPVSRS 330
Query: 363 -NLVD-------------------------------------MAAQVAAGMAYIERMNYI 384
NLV ++ Q++AGMAY+ + +Y+
Sbjct: 331 QNLVVDLEDGLRVEVEAEECEKDTQSEDRDCSGMLXTKDQLYISQQISAGMAYLAQKDYV 510
Query: 385 HRDLRSANILVGNGLICKIADFGLARLIEDNEY-TARQGAKFPIKWTAPEAALYGRFTIK 443
HRDL + + I+DFGLAR + +Y + PI+W EA LY +F+ +
Sbjct: 511 HRDL-ATRTVXSRTT*S*ISDFGLARSVHSVDYYRGSEQDAIPIRWMPLEAILYSKFSTQ 687
Query: 444 SDVWSFGILLTELV 457
SDVWSFG++L E++
Sbjct: 688 SDVWSFGVVLWEIL 729
Score = 34.3 bits (77), Expect(2) = 3e-20, Method: Compositional matrix adjust.
Identities = 15/42 (35%), Positives = 24/42 (57%)
Frame = +3
Query: 463 PYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKKDP 504
PY G+ + EV+ V+ G + P P ++ELM CW++ P
Sbjct: 744 PYYGLTHEEVVNYVKAGKILEQPTKTPHQVYELMKQCWQRRP 869
>01718
Length = 959
Score = 94.4 bits (233), Expect = 1e-19, Method: Compositional matrix adjust.
Identities = 81/266 (30%), Positives = 130/266 (48%), Gaps = 16/266 (6%)
Frame = +3
Query: 272 KKLGQGCFAEVWLGTWNGNTKVAIKTLKPGTMSPESFLEEAQIMKKLKHDKLVQLYAV-V 330
+K+G G F+EV+ T +V + T + + L E Q++ +L+H +++ V V
Sbjct: 165 EKIGAGFFSEVFKVTHRITGQVMALKMNTMTSNRHNMLREVQLLNRLQHANILRFMGVCV 344
Query: 331 SEEPIYIVTEYMNKGSLLDFLKDGEGRALKLP--NLVDMAAQVAAGMAYIERMNYIHRDL 388
E ++ +TEY+ G+L L E + +LP + + +A G+ Y+ +IHRDL
Sbjct: 345 HEGQLHALTEYIPSGNLEQLL---EKKDEELPWTQRIQLTLGLARGLDYLHSTRFIHRDL 515
Query: 389 RSANILV----GNGLICKIADFGLARLIE---DNEYTARQGAKFPIKWTAPEAALYGRF- 440
S NIL+ +G IADFGLA I D E G+ + W APE L G F
Sbjct: 516 TSKNILIRREDNHGYHAVIADFGLATKIPDPLDKEKLPTVGSPY---WMAPE-VLNGHFY 683
Query: 441 TIKSDVWSFGILLTELVTKGRVP-----YPGMNNREVLEQVERGYRMPCPQDCPISLHEL 495
++D++S GI++ E+ R+P P MNN V + V + CP+ +L
Sbjct: 684 NERADLFSVGIIMCEIT--ARIPADPDIMPRMNNFGV-DYVALSEMI---SYCPLDYLQL 845
Query: 496 MIHCWKKDPEERPTFEYLQSFLEDYF 521
C + DP++RP + +LE F
Sbjct: 846 AFKCCQVDPQKRPRGVEIIEWLEKIF 923
>17637
Length = 447
Score = 92.8 bits (229), Expect = 3e-19, Method: Compositional matrix adjust.
Identities = 46/132 (34%), Positives = 74/132 (56%), Gaps = 1/132 (0%)
Frame = +1
Query: 392 NILVGNGLICKIADFGLARLIEDNEYTARQGAKF-PIKWTAPEAALYGRFTIKSDVWSFG 450
N ++ + L K+ D L+R + +Y ++ PIKW + EA + SDVWSFG
Sbjct: 1 NCVIDDQLRVKLTDSALSRDLFSGDYNCLGDGEYRPIKWLSLEALQKSHYNEGSDVWSFG 180
Query: 451 ILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKKDPEERPTF 510
+L+ E+ T G++PY ++ E+ ++ GYR+ P +CP L +M +CW P ERP+F
Sbjct: 181 VLMWEMCTLGKLPYAEIDPYEMEHYLKDGYRLAQPFNCPDELFTIMAYCWASMPAERPSF 360
Query: 511 EYLQSFLEDYFT 522
LQ L ++ T
Sbjct: 361 SQLQICLSEFHT 396
>13592
Length = 980
Score = 90.1 bits (222), Expect = 2e-18, Method: Compositional matrix adjust.
Identities = 69/252 (27%), Positives = 130/252 (51%), Gaps = 17/252 (6%)
Frame = +2
Query: 273 KLGQGCFAEVWLGTWNGNTKV-AIK--TLKPG-TMSPESFLEEAQIMKKLKHDKLVQLYA 328
K+GQG F +V+ N ++ A+K ++PG T + ++ EE +I++ +KH LV+ Y
Sbjct: 5 KIGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETRALKNVAEELKILEGIKHKNLVRYYG 184
Query: 329 V-VSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVD--MAAQVAAGMAYIERMNYIH 385
+ V E + I E ++G+L ++ G LP + AQ+ +G+A + + +H
Sbjct: 185 IEVHREELLIFMELCSEGTLESLVELTGG----LPEALSRRFTAQLLSGVAELHKHGIVH 352
Query: 386 RDLRSANILVGNGL-ICKIADFGLARLIEDNE--------YTARQGAKFPIKWTAPEAAL 436
RD+++ANI + +G K+ DFG A I+ + Y Q P +T +
Sbjct: 353 RDIKTANIFLVDGSNSLKLGDFGSAVKIQAHTTVPGELQGYVGTQAYMAPEVFTKTNSDG 532
Query: 437 YGRFTIKSDVWSFGILLTELVTKGRVPYPGMN-NREVLEQVERGYRMPCPQDCPISLHEL 495
+GR +D+WS G ++ E+ + G+ P+ + N +++ +V G + P+ H+
Sbjct: 533 HGRL---ADIWSVGCVVVEMAS-GKRPWAQFDSNFQIMFKVGMGEKPQAPESLSQEGHDF 700
Query: 496 MIHCWKKDPEER 507
+ HC + DP++R
Sbjct: 701 IDHCLQHDPKQR 736
>14477
Length = 493
Score = 89.0 bits (219), Expect = 5e-18, Method: Composition-based stats.
Identities = 55/160 (34%), Positives = 89/160 (55%), Gaps = 8/160 (5%)
Frame = -1
Query: 271 EKKLGQGCFAEVWLGTWNGNTK---VAIKTLKPGTMSPE---SFLEEAQIMKKLKHDKLV 324
E KLG G F V G + + VAIK LK + P ++EA++MKK+ H +V
Sbjct: 475 ELKLGAGNFGSVMKGVCRLDDREIPVAIKVLKNADLDPSVQSELIKEAEVMKKMDHMHIV 296
Query: 325 QLYAVVSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYI 384
+L + E + +V E G L FL + + L L N++++ QV+ GM Y+E ++
Sbjct: 295 RLIGLCEGETMMLVLELAKLGPLNKFLP--KNKHLPLWNILELMWQVSQGMEYLEANKFV 122
Query: 385 HRDLRSANILVGNGLICKIADFGLARLI--EDNEYTARQG 422
HRDL + NIL+ + KI+DFG+++ + E+N Y A++
Sbjct: 121 HRDLAARNILLCDEHFAKISDFGMSKTLSRENNYYMAQEA 2
>13305
Length = 549
Score = 79.7 bits (195), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 35/102 (34%), Positives = 59/102 (57%), Gaps = 4/102 (3%)
Frame = +2
Query: 422 GAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYR 481
+ PI+W A E+ +T +SDVWSFG++L E+ T G PY + +++ ++ GYR
Sbjct: 2 STRVPIRWMAVESLFNNTYTTQSDVWSFGVVLWEIFTLGGTPYSSTDTQQLFAFLKDGYR 181
Query: 482 MPCPQDCPISLHELMIHCWKKDPEERPTFE----YLQSFLED 519
+ P+ C + + +M+ CW ++ + RPTF LQ L+D
Sbjct: 182 LKRPKLCDQNTYAMMLQCWNENAQRRPTFPELCGRLQRMLDD 307
>19301
Length = 712
Score = 78.6 bits (192), Expect = 6e-15, Method: Compositional matrix adjust.
Identities = 50/153 (32%), Positives = 81/153 (52%), Gaps = 3/153 (1%)
Frame = +2
Query: 258 KDAWEVARRSLCLEKKLGQGCFAEVWLGTWNGNTKVAIKTLKPGTMSPESFLEEAQI--M 315
+D WE+ S+ + LG G V+LG +VA+K ++ ++E I +
Sbjct: 281 QDDWEIPFESITDLEWLGSGAQGAVFLGKLCAE-EVAVKKVRD--------IKETDIRNL 433
Query: 316 KKLKHDKLVQLYAVVSEEPIY-IVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAG 374
+KL H ++ V ++ P Y I+ EY G L + L+DG+ L ++D + Q+A+G
Sbjct: 434 RKLNHPNIISFKGVCTQAPCYCIIMEYCPYGQLYEVLRDGKEIPPAL--VLDWSKQIASG 607
Query: 375 MAYIERMNYIHRDLRSANILVGNGLICKIADFG 407
M Y+ IHRDL+S N+LV + KI+DFG
Sbjct: 608 MNYLHSHKIIHRDLKSPNVLVAKNDVVKISDFG 706
>01756
Length = 1858
Score = 77.4 bits (189), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 60/212 (28%), Positives = 94/212 (44%), Gaps = 22/212 (10%)
Frame = -3
Query: 273 KLGQGCFAEVWLGTWNGNTKVAIKTLKPGTMS------PESFLEEAQIMKKLKHDKLVQL 326
K+GQG F EV+ +V +K M P + L E +I++ L H+ +V L
Sbjct: 1721 KIGQGTFGEVFKARCKKTKQVV--AMKKVLMDNEKEGFPITALREIKILQLLNHENVVDL 1548
Query: 327 YAVVSEEP---------IYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAY 377
+ S + Y+V E+ L L LP + ++ Q+ G+ Y
Sbjct: 1547 IEICSTKATSANRYKSMFYLVFEFCEHD--LAGLLSNMSVVFNLPEIKEVMKQLMNGLYY 1374
Query: 378 IERMNYIHRDLRSANILVGNGLICKIADFGLAR-----LIEDNEYTARQGAKFPIKWTAP 432
I R +HRD+++ANIL+ + K+ADFGLAR L + N YT R W P
Sbjct: 1373 IHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNR----VVTLWYRP 1206
Query: 433 EAALYG--RFTIKSDVWSFGILLTELVTKGRV 462
L G ++ D W G ++ E+ T+ +
Sbjct: 1205 PELLLGDRNYSTAIDQWGAGCIMAEMWTRNPI 1110
>00715
Length = 1788
Score = 76.6 bits (187), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 62/223 (27%), Positives = 103/223 (46%), Gaps = 31/223 (13%)
Frame = +1
Query: 318 LKHDKLVQLYAVVS----EEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAA 373
L+H +V + S E+ ++ EY+ +L L D + + + + +A Q+A
Sbjct: 97 LRHVNVVSILGATSLHRFEDGAWLAMEYVGPLNLQTILNDHQ-QDIDSSMRLSLALQMAR 273
Query: 374 GMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLI----------------EDNEY 417
G+ Y+ +N +H DL+ AN L+ L +IADFG + + E
Sbjct: 274 GLHYLHSINIVHLDLKPANCLLTRDLKLRIADFGCCHQLTPTGLDMGEREGGMAGNELEL 453
Query: 418 TARQGA-----KFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREV 472
T QGA + + APE + +++SDV+S GI L ++ T+ + PY G+ V
Sbjct: 454 TPVQGAWKNELAGTLAYRAPELLKGLQPSVRSDVYSLGITLWQMCTR-QGPYEGVPAHAV 630
Query: 473 LEQVERGYRMPCP----QDCP--ISLHELMIHCWKKDPEERPT 509
+ QV PCP +D P + +L CW + E+RPT
Sbjct: 631 VYQVVSKDLRPCPPPSTEDDPFEVMFRDLYTQCWARRVEDRPT 759
>12721
Length = 821
Score = 71.2 bits (173), Expect = 9e-13, Method: Compositional matrix adjust.
Identities = 51/217 (23%), Positives = 100/217 (46%), Gaps = 3/217 (1%)
Frame = +1
Query: 273 KLGQGCFAEVWLGTWNGNTKVAIKTLKPGTMSPESFL-EEAQIMKKLKHDKLVQLYA--V 329
K+G+G V + T ++A+K + L E +M+ H +V++Y +
Sbjct: 109 KIGEGSTGIVCIATSRDGRQMAVKKMDLRKQQRRELLFNEVVVMRDYHHPNIVEMYNSYL 288
Query: 330 VSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLR 389
V++E +++V E+M G+L D + + +++ + + +A++ IHRD++
Sbjct: 289 VNDE-LWVVMEFMEGGALTDIVTNNRMDEVQIATVCRACLK---ALAFLHANGVIHRDIK 456
Query: 390 SANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSF 449
S +IL+ + K+ DFG + + + P W APE + + D+WS
Sbjct: 457 SDSILLSHDGKVKLXDFGFCAQVTQDLQKRKSLVGTPY-WMAPEVISRLPYGPEVDIWSL 633
Query: 450 GILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQ 486
GI++ E++ P N L+ + R MP P+
Sbjct: 634 GIMVMEMIDAE----PPFFNEPPLQAMRRIRDMPPPK 732
>17253
Length = 483
Score = 69.7 bits (169), Expect = 3e-12, Method: Composition-based stats.
Identities = 45/153 (29%), Positives = 69/153 (45%), Gaps = 16/153 (10%)
Frame = -1
Query: 293 VAIKTLKPGTMSPE--SFLEEAQIMKKL-KHDKLVQLYAVVS-EEPIYIVTEYMNKGSLL 348
VA+KT E FL E IM+KL +H +V + +P I+ E+ G LL
Sbjct: 459 VAVKTHNEAATDAEKSEFLRELSIMRKLPRHPNVVSFMGCCTMSDPALILMEFCCHGDLL 280
Query: 349 DFLKD----------GEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNG 398
FL+ L + A VA GMA++ +HRD+ + N+L+
Sbjct: 279 SFLRKRRPDRTVFLTSTANDLTARDFFSFALHVARGMAHVANNKIVHRDVAARNVLISER 100
Query: 399 LICKIADFGLARLIEDNE--YTARQGAKFPIKW 429
+CK++DFGL+R + D Y P++W
Sbjct: 99 NVCKVSDFGLSRRVGDQNDVYEIVSRRPLPLRW 1
>01060
Length = 1800
Score = 68.9 bits (167), Expect = 4e-12, Method: Compositional matrix adjust.
Identities = 62/255 (24%), Positives = 117/255 (45%), Gaps = 13/255 (5%)
Frame = +1
Query: 261 WEVARRSLCLEKKLGQGCFAEVW------LGTWNGNTKVAIKTLKPGTMSPESFLEEAQI 314
+E A L +K+G+G + V+ G K+ ++ + G P S + E +
Sbjct: 58 FETALSDLTDFQKIGEGTYGVVYKCRHRATGRKLAMKKIRLRGSEDGV--PSSAIREIAM 231
Query: 315 MKKLKHDKLVQLYAVVSE-EPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAA 373
+++L+H +V L V+ E E +++V E+++ + K EG L + Q+
Sbjct: 232 LRELRHTNIVCLEDVIMEDERLFLVFEFLSMDLKMYIDKFPEGVVLDRRLVKSYVFQIVT 411
Query: 374 GMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPE 433
G+ + + +HRDL+ N+L+ + KIADFG+AR A + + APE
Sbjct: 412 GIXFCHQRRIVHRDLKPQNLLINHTGAIKIADFGMARTFA-LPVRAYTHEVVTLWYRAPE 588
Query: 434 AAL-YGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPISL 492
+ +++ DVWS G + +++ + + + G + + L ++ R P Q P
Sbjct: 589 ILMGASKYSTPVDVWSIGTIFADMLIRTPI-FKGDSEIDQLFKIFRIIGTPTEQTWP-EF 762
Query: 493 HEL-----MIHCWKK 502
H+L M WK+
Sbjct: 763 HKLPAFNGMFPLWKE 807
>01707
Length = 757
Score = 68.6 bits (166), Expect = 7e-12, Method: Compositional matrix adjust.
Identities = 63/216 (29%), Positives = 110/216 (50%), Gaps = 10/216 (4%)
Frame = +1
Query: 273 KLGQGCFAEVWLGTWNGNTK--VAIKTLKPGTMSP---ESFLEEAQIMKKLKHDKLVQLY 327
K+G+G + V+ N T VAIK P + + E +++K+LKH LV+L
Sbjct: 85 KIGEGSYGVVF-KCRNKETSQLVAIKKFVESEDDPLIKKIAMREIRMLKQLKHPNLVRLI 261
Query: 328 AVVSEEP-IYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHR 386
V + +++V +Y++ +LL+ L D R L P + + Q + + + N IHR
Sbjct: 262 EVFRRKKRLHLVFDYVDH-TLLNEL-DRYPRGLPEPMVKRIIYQTLLAVNFCHQYNTIHR 435
Query: 387 DLRSANILVGNGLICKIADFGLARLIE--DNEYTARQGAKFPIKWTAPEAALYG--RFTI 442
D++ NIL+ K+ DFG AR++ +EYT ++ + APE L G ++
Sbjct: 436 DVKPENILITRQGQVKLCDFGFARILTGPGDEYTDYVATRW---YRAPE-LLVGDTQYGP 603
Query: 443 KSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVER 478
DVW+ G + EL+T G+ +PG ++ + L + +
Sbjct: 604 PVDVWAIGCVFAELLT-GQALWPGRSDVDQLHLIRK 708
>18921
Length = 697
Score = 67.4 bits (163), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 53/193 (27%), Positives = 89/193 (46%), Gaps = 2/193 (1%)
Frame = +2
Query: 273 KLGQGCFAEVWLGTWNGNTKV-AIKTLKPGTMSPESFLEEAQIMKKLKHDKLVQLY-AVV 330
KLG+G + V+ +V AIK + P + ++E IM++ +V+ Y +
Sbjct: 50 KLGEGSYGSVFKSLHKETGQVLAIKQV-PVDTDLQEIIKEISIMQQCDSKYIVKYYGSYF 226
Query: 331 SEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRS 390
++IV EY GS+ D ++ + L + + G+ Y+ IHRD+++
Sbjct: 227 KNTDLWIVMEYCGAGSVSDIMRL-RNKTLVEREIATILYYTLKGLXYLHSRRKIHRDIKA 403
Query: 391 ANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFG 450
NIL+ N K+ADFG+A + D P W APE + +D+WS G
Sbjct: 404 GNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTPY-WMAPEVIQEIGYDCVADIWSLG 580
Query: 451 ILLTELVTKGRVP 463
I E+ +G+ P
Sbjct: 581 ITALEM-AEGKPP 616
>29581
Length = 1278
Score = 65.9 bits (159), Expect = 4e-11, Method: Compositional matrix adjust.
Identities = 59/191 (30%), Positives = 91/191 (47%), Gaps = 11/191 (5%)
Frame = -2
Query: 298 LKPGTMSPESFLEEAQIMKKLKHDKLVQLYAVV---SEEPIYIVTEYMNK--GSLLDFLK 352
L+ +SP + + L+H +VQL VV S + +++V EY + SLLD +
Sbjct: 1244 LERDMVSPSVVCVRSTFLLNLRHQNIVQLQEVVVGKSLDSLFLVMEYCEQDLASLLDNMP 1065
Query: 353 DGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLI 412
+ + + Q+ G+ Y+ IHRDL+ +N+L+ + KIADFGLAR
Sbjct: 1064 APFSES----QVKCIVLQLLKGLRYLHEAFIIHRDLKVSNLLMTDKGCVKIADFGLAR-- 903
Query: 413 EDNEYTARQGAKFP----IKWTAPEAALYGRFTIKS--DVWSFGILLTELVTKGRVPYPG 466
Y Q P + + APE L+G T + D+WS G +L EL+ P
Sbjct: 902 ---NYGKPQKPMTPKVVTLWYRAPE-LLFGSKTHSTAIDMWSAGCILGELLGHK----PL 747
Query: 467 MNNREVLEQVE 477
M R L+Q+E
Sbjct: 746 MPGRSDLQQIE 714
>14126
Length = 1265
Score = 64.3 bits (155), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 64/272 (23%), Positives = 124/272 (45%), Gaps = 23/272 (8%)
Frame = +3
Query: 245 IASSCTPQ-TSGLAKDAWEVARRSLCLEKK------LGQGCFAEVWLG--TWNGNTKVAI 295
+ ++ +P+ G ++ A +++RR E+K +G G + V+ N VA+
Sbjct: 105 MKTAISPKGRDGQSESAAKMSRRRDSTEQKYEEVAVIGNGAYGTVYKARDLRNQGEFVAM 284
Query: 296 KTLKPGTMS---PESFLEEAQIMKKLK---HDKLVQLYAVV------SEEPIYIVTEYMN 343
K ++ P + E ++K+L+ H +V+L V E + +V EY+
Sbjct: 285 KRIRLNNTEEGMPMMAIREISMLKQLEQYEHPNVVRLLDVSHNTITDREIRLNLVFEYI- 461
Query: 344 KGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKI 403
+ L +L L + D+ Q+ G+ ++ +HRDL+ N+L+ K+
Sbjct: 462 EHDLATYLAKCPSPGLGPDRIKDLMLQLLNGVDFLHSNRIVHRDLKPQNLLISKDGRLKL 641
Query: 404 ADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVP 463
ADFGLAR+ + + A + + +PE + + D+WS G + EL T+ R
Sbjct: 642 ADFGLARIY--SFHMALTTVVVTLWYRSPEVLMQAEYGTSVDIWSCGCIFAELFTR-RAL 812
Query: 464 YPGMNNREVLEQVERGYRMPCPQDCP--ISLH 493
+ G + + L+++ +P D P +S+H
Sbjct: 813 FKGSSEFDQLKKIFEVIGLPPAGDWPEGVSVH 908
>00300
Length = 2318
Score = 63.9 bits (154), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 57/251 (22%), Positives = 118/251 (47%), Gaps = 16/251 (6%)
Frame = -1
Query: 273 KLGQGCFAEVWLGT-WNGNTKVAIKTLK--PGTMSP-ESFLEEAQIMKKLKHDKLVQLYA 328
K+G+G F +V+ + +A+K +K P + +E +I + ++H+ LV+ Y
Sbjct: 1637 KIGEGQFGKVYTAVNMSTGELMALKEMKFQPNDLQQLREMCDEIKIFEGIQHENLVKYYG 1458
Query: 329 V-VSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPN--LVDMAAQVAAGMAYIERMNYIH 385
V V ++ + + EY + G++ + K G LP + ++ + ++ + +H
Sbjct: 1457 VEVHKDEMLMFMEYCDTGTIEEAAKMG------LPEYLIRRYTREIVLAVNHLHENSIVH 1296
Query: 386 RDLRSANILVGNGLICKIADFGLARLIEDN-----EYTARQGAK---FPIKWTAPEAALY 437
RD++ ANI + + K+ DFG + ++ + E+ G P +T + Y
Sbjct: 1295 RDIKGANIFLTSNGHVKLGDFGCSVKLKSHTTMPGEFHNLVGTTAYMAPEVFTQNDQGGY 1116
Query: 438 GRFTIKSDVWSFGILLTELVTKGRVPYPGM-NNREVLEQVERGYRMPCPQDCPISLHELM 496
GR +D+WS G ++ E+ T G+ P+ + NN +++ +V G++ P + +
Sbjct: 1115 GR---AADIWSLGCVVIEMAT-GKRPWHDLDNNYQIMYKVGIGHKPAVPDSLSVEGKHFL 948
Query: 497 IHCWKKDPEER 507
DP +R
Sbjct: 947 DLIMCHDPAQR 915
>25550
Length = 941
Score = 63.5 bits (153), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 29/63 (46%), Positives = 41/63 (65%)
Frame = +3
Query: 462 VPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKKDPEERPTFEYLQSFLEDYF 521
V YPG++ EV +ERGYRM PQ P ++ LM+ CW+ DP+ERPTF+ + LE+ F
Sbjct: 36 VXYPGVDLTEVYHLLERGYRMERPQGTPADVYILMLKCWQWDPKERPTFKEIHYLLENMF 215
Query: 522 TAT 524
+
Sbjct: 216 EKS 224
>18484
Length = 635
Score = 63.2 bits (152), Expect = 3e-10, Method: Compositional matrix adjust.
Identities = 37/122 (30%), Positives = 65/122 (53%)
Frame = +1
Query: 355 EGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIED 414
EG+ K P AA++A G+ ++ I+RDL+ N+++ + KIADFG+ +
Sbjct: 25 EGK-FKEPVAAFYAAEIAVGLFFLHDQGIIYRDLKLDNVMLDSEGHIKIADFGMCKEGMT 201
Query: 415 NEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLE 474
+ T R P + APE LY ++ D W++G+LL E++ G+ P+ G + E+
Sbjct: 202 GDATTRTFCGTP-DYIAPEIVLYQPYSKSVDWWAYGVLLFEMLA-GQPPFDGEDEDELFS 375
Query: 475 QV 476
+
Sbjct: 376 SI 381
>14420
Length = 528
Score = 61.6 bits (148), Expect = 7e-10, Method: Compositional matrix adjust.
Identities = 39/162 (24%), Positives = 79/162 (48%), Gaps = 3/162 (1%)
Frame = +2
Query: 306 ESFLEEAQIMKKLKHDKLVQ-LYAVVSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNL 364
E + E +M++ ++ +V L + + E +++V E++ GSL D + + + +
Sbjct: 35 ELIINEILVMRENQNPNIVNYLDSYLVGEELWVVMEFLAGGSLTDVVTE---TCMDEGQI 205
Query: 365 VDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLI--EDNEYTARQG 422
+ + + ++ IHRD++S NIL+G K+ DFG + E ++ + G
Sbjct: 206 AAVCRECLQALEFLHENQVIHRDIKSDNILLGMDGSVKLTDFGFCAQLSPEQSKRSTMVG 385
Query: 423 AKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPY 464
+ W APE ++ D+WS G++ E++ +G PY
Sbjct: 386 TPY---WMAPEVVTRKQYGPTVDIWSLGVMCIEMI-EGEPPY 499
>27546
Length = 426
Score = 61.2 bits (147), Expect = 1e-09, Method: Composition-based stats.
Identities = 36/114 (31%), Positives = 56/114 (49%), Gaps = 7/114 (6%)
Frame = -1
Query: 308 FLEEAQIMKKLKHDKLVQLYAVVSEEP-IYIVTEYMNKGSLLDFLKDGEGRALKLPNLVD 366
F E +I+ +L H ++Q+++++ P I+I Y KG +L +K +D
Sbjct: 339 FPRELEILTRLDHPNIIQIHSILQRGPKIFIFMRYAEKGDMLSHIKK--------TGPID 184
Query: 367 MAA------QVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIED 414
A Q+A + Y+ + HRDL+ NIL+ L KIADFG AR D
Sbjct: 183 EAQTKVWFFQMAKALQYLHSHDIAHRDLKCENILLSKRLNVKIADFGFARYCRD 22
>04591
Length = 1117
Score = 60.8 bits (146), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 44/169 (26%), Positives = 83/169 (49%), Gaps = 14/169 (8%)
Frame = -2
Query: 305 PESFLEEAQIMKKLKHDKLVQLYAVVSEEP---------IYIVTEYMN--KGSLLDFLKD 353
P + L E +I+++L+H+ +VQL + + Y++ EY + LL+ L+
Sbjct: 1089 PITALREIKILQQLEHENVVQLQEICHTQAGPYNRYKSTFYLIFEYCDYDLAGLLNNLR- 913
Query: 354 GEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLAR-LI 412
L + ++ +Q+ G+ YI +HRD+++ANIL+ + K+ADFGL+R +
Sbjct: 912 ---VKFSLADKKNLMSQLLNGLFYIHTKQILHRDIKAANILLTRDGVLKLADFGLSRPWV 742
Query: 413 EDNEYTARQGAKFPIKWTAPEAALYG--RFTIKSDVWSFGILLTELVTK 459
+ T R W P L G + + D+W G ++ E+ ++
Sbjct: 741 KSKRLTNR----VVTLWYRPPELLLGEREYGPEIDMWGVGCIMAEMWSR 607
>00392
Length = 668
Score = 58.5 bits (140), Expect = 6e-09, Method: Compositional matrix adjust.
Identities = 53/174 (30%), Positives = 88/174 (50%), Gaps = 10/174 (5%)
Frame = +3
Query: 306 ESFLEEAQIMKKLKHDKLVQLYAVVSE------EPIYIVTEYMNKGSLLDFLKDGEGRAL 359
+ F EEA+++K+L+H +V+ + E + I +VTE M G+L +LK + +
Sbjct: 66 QRFKEEAEMLKELQHPNIVRFFDYWEEHNHRNRKVIILVTELMTSGTLKTYLKRFKKPNV 245
Query: 360 KLPNLVDMAAQVAAGMAYIERMN--YIHRDLRSANILV-GNGLICKIADFGLARLIEDNE 416
K+ L + QV G+ ++ IHRDL+ NI + G KI D GLA L N+
Sbjct: 246 KI--LKNWCRQVLKGLYFLHTRTPPVIHRDLKCDNIFITGPTGSVKIGDLGLATL--KNQ 413
Query: 417 YTARQGAKFPIKWTAPEAALY-GRFTIKSDVWSFGILLTELVTKGRVPYPGMNN 469
A+ P ++ APE +Y + DV++FG+ + E+ + PY +N
Sbjct: 414 SFAKSVIGTP-EFMAPE--MYEEHYDEAVDVYAFGMCMLEMAS-SEYPYSECSN 563
>01966
Length = 1735
Score = 58.2 bits (139), Expect = 7e-09, Method: Compositional matrix adjust.
Identities = 32/107 (29%), Positives = 58/107 (54%), Gaps = 1/107 (0%)
Frame = -1
Query: 305 PESFLEEAQIMKKLKHDKLVQLYAVVSE-EPIYIVTEYMNKGSLLDFLKDGEGRALKLPN 363
P S + E ++++L+H +V L V+ E E +++V E+++ + K EG L
Sbjct: 1582 PSSAIREIAMLRELRHTNIVCLEDVIMEDERLFLVFEFLSMDLKMYIDKFPEGVVLDRRL 1403
Query: 364 LVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLAR 410
+ Q+ G+ + + +HRDL+ N+L+ + KIADFG+AR
Sbjct: 1402 VKSYVFQIVTGINFCHQRRIVHRDLKPQNLLINHTGAIKIADFGMAR 1262
>11228
Length = 2155
Score = 58.2 bits (139), Expect = 8e-09, Method: Compositional matrix adjust.
Identities = 41/149 (27%), Positives = 75/149 (50%), Gaps = 5/149 (3%)
Frame = -2
Query: 88 VALYDYEARTE-DDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYVAPVDS--- 143
VA+ Y T+ D+LSF KG+ F + N E W T E+G +P+ +V +D
Sbjct: 1662 VAMLSYRKATDSDELSFCKGDVFVVQNEMEDGWLWVTCERTKESGLVPAPFVKDLDGDYE 1483
Query: 144 -IQAEEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDWDDMKGDHVKH 202
+++ ++ L +++A +L+ G G+FL+R+SE G YSL D V+
Sbjct: 1482 PVESLPYFHSCLSKEEAVEKLMLAGE--GSFLVRQSENYPGDYSLFFLCEKD-----VRR 1324
Query: 203 YKIRKLDNGGYYITTRAQFETLQQLVQHY 231
++I + G ++ F++L +++ Y
Sbjct: 1323 FRIER--RGNQFLVGGRLFDSLDGVIKRY 1243
Score = 37.0 bits (84), Expect = 0.018, Method: Compositional matrix adjust.
Identities = 22/57 (38%), Positives = 31/57 (54%)
Frame = -1
Query: 132 YIPSNYVAPVDSIQAEEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLS 188
+I S AP + WY G+LGR AE L G++L+RESE+ G++ LS
Sbjct: 2011 HINSALTAPDQKL----WYHGRLGRAGAEELLRD--QDAGSYLVRESESKLGSFVLS 1859
>31885
Length = 529
Score = 57.0 bits (136), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 46/169 (27%), Positives = 78/169 (46%), Gaps = 6/169 (3%)
Frame = -2
Query: 312 AQIMKKLKHDKLVQL-YAVVSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQ 370
++ +L H LV L YA EE +++V + G L ++ + + + + Q
Sbjct: 519 VDMLTRLDHPFLVNLWYAFQDEEDLFMVVDLFLGGDLRYHMQ--QEVSFREDCVKFYLCQ 346
Query: 371 VAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWT 430
+A + Y+ +HRD++ NIL+ C + DF +A +ED+E P +
Sbjct: 345 LALVLDYLRSQKIVHRDIKPDNILLDEQGHCHVTDFNIATQLEDDELATSTSGTRP--YM 172
Query: 431 APE---AALYGR--FTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLE 474
APE A+ R + D WS G+ L EL+ K R P+ +N + E
Sbjct: 171 APEVYGVAINERRGYGFPVDWWSLGVSLFELLKKRR-PFSVHSNTSLHE 28
>07836
Length = 1478
Score = 56.6 bits (135), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 62/217 (28%), Positives = 100/217 (46%), Gaps = 42/217 (19%)
Frame = -1
Query: 335 IYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIE--------RMNYIHR 386
++++T+Y GSL D+L R L ++ +A G+A++ + HR
Sbjct: 1328 LFLITDYHENGSLHDYLL---SRVLDSSEMLALAHSAICGLAHLHIEIFGTRGKPAIAHR 1158
Query: 387 DLRSANILVGNGLICKIADFGLA-RLI-EDNEYTA----RQGAKFPIKWTAPEAALYGRF 440
D++S NILV C IAD GLA R I E NE RQG K ++ APE L
Sbjct: 1157 DIKSKNILVKKNGTCCIADLGLAVRYISESNEVDVAPNPRQGTK---RYMAPE-VLEMLL 990
Query: 441 TIK-------SDVWSFGILLTEL----VTKG-----RVPY-------PGMNNREVLEQVE 477
+K +D+++FG+++ E+ V G +VP+ P + ++ V+
Sbjct: 989 NVKNFDAFKQADMYAFGLVMWEIARCCVIGGVAEEYQVPFYNCLPHDPSFEDVRLVVSVD 810
Query: 478 RGYRMPCP---QDCPI--SLHELMIHCWKKDPEERPT 509
+ R P Q+ PI + ++M CW +P R T
Sbjct: 809 K-VRPDIPLRWQEDPIMKVMVKVMCECWSGNPAARLT 702
>13066
Length = 551
Score = 56.6 bits (135), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 48/183 (26%), Positives = 81/183 (44%), Gaps = 12/183 (6%)
Frame = +3
Query: 280 AEVWLGTWNG----NTKVAIKTL----KPGTMSPESFLEEAQIMKKLKHDKLVQLYAVVS 331
A V GT+N N K+A K + P + F E ++ KL H ++Q+++++
Sbjct: 9 AVVVHGTFNDGYGRNIKLACKIIDKEKAPVDFVEKFFPRELDLLTKLDHPYIIQIHSILQ 188
Query: 332 EEPI-YIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRS 390
P +I + +G LL +++ E +K Q+ + Y+ + HRDL+
Sbjct: 189 RXPKNFIFMRFAERGDLLTYIQ--EVGFVKEKQAKIWFYQMTTALNYLHSYDVAHRDLKC 362
Query: 391 ANILVGNGLICKIADFGL--ARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIK-SDVW 447
NIL+ + K+ADFG A + E E + + APE + K +D W
Sbjct: 363 ENILLSSHFNVKLADFGFACACITESGEKYMSRTYCGSAAYAAPEIVYGAPYAPKVADAW 542
Query: 448 SFG 450
S G
Sbjct: 543 SLG 551
>09606
Length = 1300
Score = 55.1 bits (131), Expect = 8e-08, Method: Compositional matrix adjust.
Identities = 52/223 (23%), Positives = 96/223 (43%), Gaps = 23/223 (10%)
Frame = -3
Query: 267 SLCLEKKLGQGCFAEVWLGTWNGNTK-VAIKTLKPGTMSPESFLEEAQIMKKLKHDKLVQ 325
+ L ++LG+G + ++ G G VAI ++ PE ++ + H +VQ
Sbjct: 1112 NFVLYEELGKGEHSIIYKGRRKGTINFVAIHCIEK-CKRPE-VTNTVRMTHDISHPNVVQ 939
Query: 326 LYA-VVSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYI 384
+ + +++V E GSL D L + L ++ D + G+ YI + +
Sbjct: 938 FHEWYETSNHLWLVVELCTGGSLADIL--AQDHHLPETSIRDFGIHLVTGLHYIHSLGIL 765
Query: 385 HRDLRSANILVGNGLICKIADFGLARLIEDNEYT-----ARQGAKFPIK----------- 428
DLR + +L+ + K ADFGL+++ +N A G ++ I+
Sbjct: 764 FHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQWNIQSAEEMMKQVPT 585
Query: 429 -----WTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPG 466
+ APE +I SD+W+ G + E+ + G P+ G
Sbjct: 584 SGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFS-GHPPFLG 459
>03240
Length = 1683
Score = 54.7 bits (130), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 46/161 (28%), Positives = 75/161 (46%), Gaps = 9/161 (5%)
Frame = -3
Query: 272 KKLGQGCFAEVWLGTWNGNTKV-AIKTLKPGTMSPESFLE----EAQIMKKLKHDKLVQL 326
K LG G F EV L N + A+KTL+ + + + E I+ + ++ +V+L
Sbjct: 1273 KTLGVGAFGEVSLCRKNDTGMLYAMKTLRKSDVLKRNQVAHVKAERDILAEADNEWVVKL 1094
Query: 327 YAVVSEEP-IYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIH 385
Y + +Y V +Y+ G L+ L E L P A++ + + RM +IH
Sbjct: 1093 YYSFQDHNYLYFVMDYVPGGDLMGLLIRME--ILDEPLARFYVAELVQAIESVHRMGFIH 920
Query: 386 RDLRSANILVGNGLICKIADFGLA---RLIEDNEYTARQGA 423
RD++ NIL+ K+ DFGL R +++Y R G
Sbjct: 919 RDIKPDNILIDRNGHIKLTDFGLCTGFRWTHNSKYYQRDGT 797
>12672
Length = 773
Score = 53.9 bits (128), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 40/164 (24%), Positives = 74/164 (45%), Gaps = 16/164 (9%)
Frame = +3
Query: 372 AAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPI---K 428
A+G+ Y+ ++HRD+++ANIL+ + K+ DF E Q A I
Sbjct: 21 ASGIQYLNDNGHVHRDIKTANILLDSEYTAKVGDFATVVSAPSGEGKTVQNASVVIGTAA 200
Query: 429 WTAPEAALYGRFTIKSDVWSFGILLTELVT----------KGRVPYPGMNNREVLEQVER 478
+ APE A++ + K D +SFG++L E++T + + M N E E++
Sbjct: 201 YLAPE-AIHFDVSTKLDSYSFGVVLLEVITGLVAQDYSREERTLSSHIMENVEEPEEIHD 377
Query: 479 GYRMPC---PQDCPISLHELMIHCWKKDPEERPTFEYLQSFLED 519
P L+++ + C ++RP + ++ LE+
Sbjct: 378 FVDQSAGTWPDGAVDKLYDISMRCLNLSKKQRPNVKDIRPELEE 509
>13212
Length = 1067
Score = 53.1 bits (126), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 45/167 (26%), Positives = 76/167 (45%), Gaps = 11/167 (6%)
Frame = -1
Query: 370 QVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKF---P 426
++ + ++ R + IHRD+++ N+L+ K+ADFG++ N T ++ F P
Sbjct: 956 EMCMALDFLHRHHVIHRDIKAGNVLLTIDGEVKLADFGVSA---KNTQTQQKRDTFIGTP 786
Query: 427 IKWTAPEAALY-----GRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERG-- 479
W APE L + K+D+WS G+ L E + P M+ VL ++ +
Sbjct: 785 Y-WMAPEVVLCETLKDTPYDFKADIWSLGVTLIEFA-QIEPPNKEMHPMRVLIKIHKSDP 612
Query: 480 YRMPCPQDCPISLHELMIHCWKKDPEERPT-FEYLQSFLEDYFTATE 525
+ P+ + + C KDP RPT E L+ TAT+
Sbjct: 611 PTLEKPKKWTKLFKDFIAKCLVKDPNLRPTAAELLEHPFMKRATATD 471
>04138
Length = 800
Score = 52.4 bits (124), Expect = 4e-07, Method: Compositional matrix adjust.
Identities = 32/95 (33%), Positives = 48/95 (50%), Gaps = 7/95 (7%)
Frame = +1
Query: 375 MAYIERMNYIHRDLRSANILVGNGLICKIADFGLAR-----LIEDNEYTARQGAKFPIKW 429
+ YI R +HRD+++ANIL+ + K+ADFGLAR L + N YT R W
Sbjct: 52 LYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNR----VVTLW 219
Query: 430 TAPEAALYG--RFTIKSDVWSFGILLTELVTKGRV 462
P L G ++ D W G ++ E+ T+ +
Sbjct: 220 YRPPELLLGDRNYSTAIDQWGAGCIMAEMWTRNPI 324
>29243
Length = 1147
Score = 51.6 bits (122), Expect = 7e-07, Method: Compositional matrix adjust.
Identities = 35/107 (32%), Positives = 55/107 (51%), Gaps = 4/107 (3%)
Frame = +2
Query: 136 NYVAPVDSIQAEEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETT--KGAYSLSIRDWD 193
+YV S+++ WY G + R A++ L + P GTFLIR + +G SLSI+
Sbjct: 269 DYVNEPCSLESYNWYVGIMERPVAQKXLDTC--PDGTFLIRVTNNPLRRGELSLSIK--- 433
Query: 194 DMKGDHVKHYKIRKLDNGGYYITTRAQFETLQQLVQHY--SEKADGL 238
+ V+H K+ + G +Y+ F+ +Q LV HY +E AD
Sbjct: 434 --YANAVRHIKVNRNPQGRFYLADGRYFDNIQSLVDHYENNELADSF 568
Score = 40.4 bits (93), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 21/58 (36%), Positives = 30/58 (51%), Gaps = 2/58 (3%)
Frame = +2
Query: 88 VALYDYEARTEDDLSFHKGEKFQIL--NSSEGDWWEARSLTTGETGYIPSNYVAPVDS 143
VA+YDY A + LS ++ IL N + WW+ +L T + GY P YV D+
Sbjct: 641 VAVYDYAATSTSQLSMKLNDRIAILSKNGQDKGWWKGENLRTQKIGYFPLAYVDEEDA 814
>21079
Length = 878
Score = 51.6 bits (122), Expect = 8e-07, Method: Compositional matrix adjust.
Identities = 39/143 (27%), Positives = 69/143 (48%), Gaps = 4/143 (2%)
Frame = +1
Query: 320 HDKLVQLY-AVVSEEPIYIVTEYMNKGSLLD-FLKDGEGRALKLPNLVDMAAQVAAGMAY 377
H KL+ L+ A + + +V E++ G L + ++D L + V Q+ +G+ Y
Sbjct: 1 HPKLLMLWDAFEAPRTMVLVMEFVGAGELFERVIRDD--FVLTERDCVHFVRQICSGVGY 174
Query: 378 IERMNYIHRDLRSANILV--GNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAA 435
+ + +H DL+ N+L N KI DFGLAR + + + Q ++ APE
Sbjct: 175 MHTQSILHLDLKPENVLCVSDNSNQIKIIDFGLARFYKPGD--SLQVLFGTPEFIAPEVV 348
Query: 436 LYGRFTIKSDVWSFGILLTELVT 458
Y +D+WS G++ L++
Sbjct: 349 NYDEINFTTDMWSIGVICYILLS 417
>12324
Length = 946
Score = 48.9 bits (115), Expect = 5e-06, Method: Compositional matrix adjust.
Identities = 22/53 (41%), Positives = 32/53 (60%)
Frame = +3
Query: 88 VALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYVAP 140
VA+YDYEA +D+L+F + ++ ++ WWE + G TG PSNYV P
Sbjct: 699 VAIYDYEAEKDDELTFSENSVIYVIRKNDDGWWEG--VMDGVTGLFPSNYVEP 851
>19094
Length = 898
Score = 48.5 bits (114), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 28/83 (33%), Positives = 41/83 (49%)
Frame = +1
Query: 374 GMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPE 433
G+ Y+ IHRD+++ NIL+ N K+ADFG+A + D P W APE
Sbjct: 94 GL*YLHSRRKIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTP-YWMAPE 270
Query: 434 AALYGRFTIKSDVWSFGILLTEL 456
+ +D+WS GI E+
Sbjct: 271 VIQEIGYDCVADIWSLGITALEM 339
>15910
Length = 1361
Score = 47.8 bits (112), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 34/114 (29%), Positives = 57/114 (50%), Gaps = 3/114 (2%)
Frame = +2
Query: 369 AQVAAGMAYIERMNYIHRDLRSANIL---VGNGLICKIADFGLARLIEDNEYTARQGAKF 425
+ + G+ YI +HRDL+ N+L + + K+ADFGL+R+IE E
Sbjct: 485 SDILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLADFGLSRIIEP-EVQMSTVCGT 661
Query: 426 PIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERG 479
P + APE ++T D+WS G++ L+ G P+ N E+ ++ +G
Sbjct: 662 P-GYCAPEVLKGDKYTPSVDMWSVGVIAYILLC-GYEPFFAENEFEMYRKIIKG 817
>30755
Length = 1137
Score = 47.4 bits (111), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 37/142 (26%), Positives = 66/142 (46%), Gaps = 2/142 (1%)
Frame = +2
Query: 368 AAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEY--TARQGAKF 425
A++ + + Y+ I+RDL+ N+L+ K+ADFGL + ED Y T +
Sbjct: 50 GAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCK--EDITYGRTTKTFCGT 223
Query: 426 PIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCP 485
P ++ APE + D W G+++ E++ GR+P+ + +VL + + P
Sbjct: 224 P-EYLAPEVLDDNDYGRAVDWWGTGVVMYEMIC-GRLPFYN-RDHDVLFTLILVEDVKFP 394
Query: 486 QDCPISLHELMIHCWKKDPEER 507
++ L+ KDP R
Sbjct: 395 RNITDEAKSLLSGLLAKDPRNR 460
>21210
Length = 518
Score = 45.8 bits (107), Expect = 5e-05, Method: Compositional matrix adjust.
Identities = 34/86 (39%), Positives = 47/86 (54%), Gaps = 4/86 (4%)
Frame = +3
Query: 432 PEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPG-MNNREVLEQVERGYRMPC-PQDCP 489
P A+ +G + ++SDVWS GI L EL T GR PY ++ + L+QV RG PC P D
Sbjct: 42 PRASSHG-YDVRSDVWSLGITLMELAT-GRFPYRKWVSIFDQLQQVVRGV-APCLPHDGA 212
Query: 490 IS--LHELMIHCWKKDPEERPTFEYL 513
S + C KD ++RP + L
Sbjct: 213 FSHDFVNFVNKCLTKDEKQRPKYNKL 290
>19761
Length = 473
Score = 45.1 bits (105), Expect = 7e-05, Method: Compositional matrix adjust.
Identities = 34/119 (28%), Positives = 54/119 (45%), Gaps = 3/119 (2%)
Frame = -3
Query: 370 QVAAGMAYIERMN--YIHRDLRSANILVGNGLICKIADFGLAR-LIEDNEYTARQGAKFP 426
Q A+ + Y+ +HRDL+ NI V ++ D GLAR L ++ Q
Sbjct: 399 QTASALNYMHTHTPVILHRDLKPQNIYVTEKGDVRLGDLGLARKLTGPADFATSQVGT-- 226
Query: 427 IKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCP 485
I + +PE + KSD+WS G + ++ G+ M +L QV G ++P P
Sbjct: 225 IMYLSPEILSQQPYNSKSDIWSLGCVFYDIT--GKKGSDEMGVMFLLVQVMGGRKLPLP 55
>29687
Length = 434
Score = 45.1 bits (105), Expect = 8e-05, Method: Compositional matrix adjust.
Identities = 22/55 (40%), Positives = 32/55 (58%)
Frame = -2
Query: 89 ALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYVAPVDS 143
AL+DY A+ ED+LSF KG ++ +G WW T + + PSNYV +D+
Sbjct: 286 ALHDYNAKREDELSFCKGAIITNVSRQDGGWWRG-DYGTKKQHWFPSNYVEEIDT 125
>26560
Length = 398
Score = 44.7 bits (104), Expect = 1e-04, Method: Composition-based stats.
Identities = 32/102 (31%), Positives = 52/102 (50%), Gaps = 1/102 (0%)
Frame = -1
Query: 368 AAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPI 427
AA+V G+ ++ ++RDL+ ANIL+ +I+D GLA A G
Sbjct: 338 AAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGLACDFSKKRPHASVGTH--- 168
Query: 428 KWTAPEAALYGR-FTIKSDVWSFGILLTELVTKGRVPYPGMN 468
+ APE + G+ + +D +SFG +L +L+ KG P+ N
Sbjct: 167 GYMAPEVLMKGQSYDSSADWFSFGCMLYKLL-KGHSPFRQHN 45
>11185
Length = 473
Score = 44.3 bits (103), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 35/142 (24%), Positives = 61/142 (42%), Gaps = 25/142 (17%)
Frame = +1
Query: 366 DMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYT-----AR 420
D + G+ YI + + DLR + +L+ + K ADFGL+++ +N A
Sbjct: 13 DFGIHLVTGLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAE 192
Query: 421 QGAKFPIK----------------WTAPEAALYGRFTIKSDVWSFGILLTELVTKGRV-- 462
G ++ I+ + APE +I SD+W+ G + E+ + R+
Sbjct: 193 AGDQWNIQSAEEMMKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSGSRLSA 372
Query: 463 -PYPG-MNNREVLEQVERGYRM 482
P P +N E L Q + R+
Sbjct: 373 KPSPEFLNLLESLLQKDSTRRL 438
>14257
Length = 919
Score = 44.3 bits (103), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 28/89 (31%), Positives = 47/89 (52%)
Frame = -3
Query: 147 EEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDWDDMKGDHVKHYKIR 206
EEWY GK+GRK+AE+ L G FL+RE+ + + LS R + +V+H +
Sbjct: 896 EEWYHGKIGRKEAEKLL----ELDGDFLVREASNSAAQFVLSGR-----QNGNVRHLLL- 747
Query: 207 KLDNGGYYITTRAQFETLQQLVQHYSEKA 235
+D G T F+++ L+ ++ + A
Sbjct: 746 -VDPDGIVRTKDFIFDSVSHLINYHRQNA 663
>01106
Length = 878
Score = 43.5 bits (101), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 38/140 (27%), Positives = 69/140 (49%), Gaps = 16/140 (11%)
Frame = +3
Query: 272 KKLGQGCFAEVWLGTWNGNTK--VAIKTLKPGTMSPESFLEEAQIMKKLKHD-------- 321
+KLG G F+ VWL W+ K VA+K +K E+ L+E +++K ++
Sbjct: 336 RKLGWGHFSTVWL-CWDLTCKRFVALKVVKSAQHYTETALDEVKLLKCVRESDVADPARA 512
Query: 322 KLVQLY-----AVVSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMA 376
K VQL + V+ + +V E + +LL + + + + N+ + QV G++
Sbjct: 513 KCVQLLDDFKISGVNGTHVAMVFEVLGY-NLLKLIIRSNYQGIPIHNVKLIIRQVLEGLS 689
Query: 377 YIE-RMNYIHRDLRSANILV 395
Y+ + IH D++ NIL+
Sbjct: 690 YMHAKCRIIHTDIKPENILI 749
>28638
Length = 1458
Score = 42.4 bits (98), Expect = 5e-04, Method: Compositional matrix adjust.
Identities = 35/109 (32%), Positives = 53/109 (48%), Gaps = 5/109 (4%)
Frame = -1
Query: 355 EGRALKLPNLVDMAAQVAAGMAYIE--RMNYIHRDLRSANILVGN---GLICKIADFGLA 409
EG +L L A Q+ + ++ MN IH DL+ NIL+ N I KI DFG +
Sbjct: 852 EGVSLNLTR--KFAQQLCTALLFLATPEMNIIHCDLKPENILLCNPKRSAI-KIVDFGSS 682
Query: 410 RLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVT 458
+ Y Q ++F + +PE L + + D+WS G +L E+ T
Sbjct: 681 CQLGQRIYQYIQ-SRF---YRSPEVLLGVPYDLAIDMWSLGCILVEMHT 547
>28095
Length = 597
Score = 41.6 bits (96), Expect = 8e-04, Method: Compositional matrix adjust.
Identities = 19/54 (35%), Positives = 30/54 (55%)
Frame = +3
Query: 89 ALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYVAPVD 142
A+YDY+A D++SF+ G+ + W R TG+ G +PSNYV ++
Sbjct: 270 AMYDYQAADSDEVSFNDGDTIIECQPVDAGWMTGRVERTGQYGMLPSNYVERIN 431
>12786
Length = 460
Score = 41.2 bits (95), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 27/107 (25%), Positives = 51/107 (47%), Gaps = 21/107 (19%)
Frame = -3
Query: 384 IHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPI-KWTAPEAALYG---- 438
IH DL+ AN ++ G + K+ DFG+A ++ ++ + + ++ + +PEA +
Sbjct: 344 IHSDLKPANFMLVAGNL-KLIDFGIANTLQQDKTSVLKDSRVGTPSYMSPEAIMAACDDS 168
Query: 439 ----------------RFTIKSDVWSFGILLTELVTKGRVPYPGMNN 469
+ ++SDVWS G +L +V GR P+ + N
Sbjct: 167 ADDSMEEDGHRTKPKYKVGVRSDVWSLGCILYNMVY-GRTPFQHIKN 30
>26711
Length = 405
Score = 41.2 bits (95), Expect = 0.001, Method: Composition-based stats.
Identities = 31/111 (27%), Positives = 54/111 (48%), Gaps = 3/111 (2%)
Frame = -2
Query: 370 QVAAGMAYIERMNYIHRDLRSANILVGNGLI--CKIADFGLAR-LIEDNEYTARQGAKFP 426
QV + ++ +H DL+ +N+L+ + ++ DFGLAR L E G
Sbjct: 392 QVLDILQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARKLYPPQETFLNHGTP-- 219
Query: 427 IKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVE 477
+T+PEA + SDVW G+L L++ G+ P+ + E L++ +
Sbjct: 218 -GFTSPEALDVKPISTASDVWGVGVLAYILLS-GQSPFQADSATESLKKTQ 72
>05206
Length = 1075
Score = 41.2 bits (95), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 19/50 (38%), Positives = 27/50 (54%)
Frame = +1
Query: 89 ALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYV 138
ALY +EA E + + E+ QIL +GD W G G++PS+YV
Sbjct: 103 ALYPFEAMNEGSVPMGENEEMQILEEDQGDGWTRVRKADGSEGFVPSSYV 252
>37602
Length = 804
Score = 40.8 bits (94), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 23/77 (29%), Positives = 37/77 (48%)
Frame = -1
Query: 330 VSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLR 389
+ E ++I EY GS+ D L P + + + G+ Y+ R +HRD++
Sbjct: 309 LRREKLWIAMEYCGGGSMQDIYH--VTGPLTEPQIAFVCRETLKGLHYLHRRGKMHRDIK 136
Query: 390 SANILVGNGLICKIADF 406
ANIL+ K+ADF
Sbjct: 135 GANILLTEEGDVKLADF 85
>01494
Length = 2122
Score = 40.4 bits (93), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 30/107 (28%), Positives = 49/107 (45%), Gaps = 5/107 (4%)
Frame = +3
Query: 89 ALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYVAPVDS---IQ 145
AL+DY A +D+LSF KG ++ +G WW + + PSN+V +++ +
Sbjct: 318 ALHDYNANRDDELSFCKGAIITNVSRQDGGWWRG-DYGAKKQHWFPSNFVEEIETHSDVN 494
Query: 146 AEEWYFGKL--GRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIR 190
++ G L G D + L+ PRG K A+ +S R
Sbjct: 495 SDSMPLGSLQQGSFDIQGCLVEPLAPRG---------DKSAFRISTR 608
>18481
Length = 437
Score = 40.0 bits (92), Expect = 0.003, Method: Composition-based stats.
Identities = 21/65 (32%), Positives = 37/65 (56%), Gaps = 3/65 (4%)
Frame = -1
Query: 357 RALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICK---IADFGLARLIE 413
R L ++ ++ Q+ + + +I + +IHRDL+ N L+G G C I DFGL++ +
Sbjct: 212 RRFTLKTILMVSDQLLSRLEFIHQKCFIHRDLKPDNFLMGLGRHCHRLYIIDFGLSKRYK 33
Query: 414 DNEYT 418
D + T
Sbjct: 32 DTQGT 18
>32000
Length = 644
Score = 39.7 bits (91), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 29/85 (34%), Positives = 45/85 (52%), Gaps = 3/85 (3%)
Frame = -1
Query: 402 KIADFGLARL--IEDNEYTARQGAKFPIKWTAPEAALYGRF-TIKSDVWSFGILLTELVT 458
KIADFGLAR+ + YT + + APE L RF ++ D+WS G + E++T
Sbjct: 569 KIADFGLARVFGLPVRTYTHEVIT---LWYRAPEILLGCRFYSVPVDIWSLGCIFVEMMT 399
Query: 459 KGRVPYPGMNNREVLEQVERGYRMP 483
+ R +PG + + L ++ R P
Sbjct: 398 R-RALFPGDSEIDQLYRIFRTLGTP 327
>32264
Length = 287
Score = 39.7 bits (91), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 18/44 (40%), Positives = 29/44 (65%)
Frame = +1
Query: 476 VERGYRMPCPQDCPISLHELMIHCWKKDPEERPTFEYLQSFLED 519
+E GYR+ P S+++LM+ CW+ PE+RP F+ L + L+D
Sbjct: 1 IEDGYRLQQNPQTPDSVYKLMLRCWEYVPEKRPHFKELYTSLKD 132
>16708
Length = 1397
Score = 39.3 bits (90), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 35/149 (23%), Positives = 74/149 (49%), Gaps = 11/149 (7%)
Frame = -1
Query: 274 LGQGCFAEVWLG-TWNGNTKVAIKTLKPGTMSPESFLEEAQIMKKLKHD-KLVQLY-AVV 330
LG+G F +V+ + + K A+KT ++ L+E + + +++ L Q++ A V
Sbjct: 1379 LGKGVFGKVYEARLLSTHEKAALKT----SILCHHSLDEVEALGRIEGGFYLAQMFGAWV 1212
Query: 331 SEEP---IYIVTEYMNKGSLLDFLKDGEGRALKL----PNLVD-MAAQVAAGMAYIERMN 382
+ P + I+ + G L + + + + + P +V +A Q + +I +
Sbjct: 1211 TCLPFPKMNILLHFYEMGPLCNVYAHYKNKEMPIRWSNPAMVCCIAGQXVCALEHIHELG 1032
Query: 383 YIHRDLRSANILVGNGLICKIADFGLARL 411
+H D+++ N+LV CK+ D+G+A+L
Sbjct: 1031 VVHMDVKADNVLVDAHGNCKLTDYGIAQL 945
>35671
Length = 567
Score = 38.5 bits (88), Expect = 0.007, Method: Compositional matrix adjust.
Identities = 15/47 (31%), Positives = 28/47 (59%)
Frame = -3
Query: 477 ERGYRMPCPQDCPISLHELMIHCWKKDPEERPTFEYLQSFLEDYFTA 523
++G R+ P C +++M+ CW + EERPTF+ L +E+ + +
Sbjct: 565 QKGNRLAKPISCTDEAYKVMLQCWTESREERPTFKKLVPVMENLYRS 425
>00394
Length = 548
Score = 37.7 bits (86), Expect = 0.011, Method: Compositional matrix adjust.
Identities = 29/98 (29%), Positives = 50/98 (51%), Gaps = 11/98 (11%)
Frame = -2
Query: 266 RSLCLEKKLGQGCFAEVWLGTWNGNTKVAI-----KTLKPGTMSPESFLEEAQIMKKLKH 320
R L +K++G+G F V+ G + VA+ + K + F EEA+++K+L+H
Sbjct: 298 RFLKFDKEIGRGSFKTVYKGL-DTELGVAVAWCELQDKKWNKAERQRFKEEAEMLKELQH 122
Query: 321 DKLVQLYAVVSE------EPIYIVTEYMNKGSLLDFLK 352
+V+ + E + I +VTE M G+L +LK
Sbjct: 121 PNIVRFFDYWEEHNHRNRKVIILVTELMTSGTLKTYLK 8
>16716
Length = 934
Score = 37.7 bits (86), Expect = 0.013, Method: Compositional matrix adjust.
Identities = 28/111 (25%), Positives = 44/111 (39%)
Frame = -1
Query: 28 YRYGTDPTPQHYPSFGVTSIPNYNNFHAAGGQGLTVFGGVNSSSHXXXXXXXXXXXXXXF 87
Y +P PQH P + + A Q GG +++
Sbjct: 577 YEVSEEPAPQHEPEESPYEMADEEPAAPAQSQP----GGGSTA----------------- 461
Query: 88 VALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYV 138
+ALYDY+A +D+L+F + + + WW R G+ G P+NYV
Sbjct: 460 IALYDYQAADDDELTFDPDDVITDIEMIDDGWW--RGSCHGKNGLFPANYV 314
>27405
Length = 532
Score = 37.4 bits (85), Expect = 0.014, Method: Compositional matrix adjust.
Identities = 32/121 (26%), Positives = 52/121 (42%)
Frame = -3
Query: 327 YAVVSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHR 386
YA + E + + + MN G L L + + AA+V G+ ++ ++R
Sbjct: 353 YAFQTPEKLCFILDLMNGGDLHYHLS--QHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYR 180
Query: 387 DLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDV 446
DL+ ANIL+ +I+D GLA + A G + APE + G+ S
Sbjct: 179 DLKPANILLDENGHVRISDLGLACDFSKKKPHASVGTH---GYMAPEVLMKGQAYDSSAD 9
Query: 447 W 447
W
Sbjct: 8 W 6
>17286
Length = 489
Score = 37.4 bits (85), Expect = 0.015, Method: Composition-based stats.
Identities = 17/56 (30%), Positives = 31/56 (55%)
Frame = +3
Query: 89 ALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYVAPVDSI 144
A+YD+ ++ +L F +G+ +++ + +W+E G+ GY P NYV V I
Sbjct: 36 AIYDFLPESDGELGFQEGDMITLISQVDENWFEGS--VHGKVGYFPINYVEVVVPI 197
>30740
Length = 488
Score = 37.4 bits (85), Expect = 0.017, Method: Compositional matrix adjust.
Identities = 13/33 (39%), Positives = 21/33 (63%)
Frame = +2
Query: 91 YDYEARTEDDLSFHKGEKFQILNSSEGDWWEAR 123
YD+ R +DL F KG+ ++++ E +WW AR
Sbjct: 203 YDFSGRDPEDLPFSKGDILELISKDEEEWWTAR 301
>38046
Length = 446
Score = 36.6 bits (83), Expect = 0.023, Method: Composition-based stats.
Identities = 15/26 (57%), Positives = 20/26 (76%)
Frame = -1
Query: 371 VAAGMAYIERMNYIHRDLRSANILVG 396
+A MAY+E+ N+IHR+L NILVG
Sbjct: 98 IADAMAYMEKENFIHRNLGDRNILVG 21
>06462
Length = 1511
Score = 36.2 bits (82), Expect = 0.032, Method: Compositional matrix adjust.
Identities = 27/99 (27%), Positives = 43/99 (43%)
Frame = +1
Query: 133 IPSNYVAPVDSIQAEEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDW 192
+PS+ D E WY GK+ R++AE+ L G FL+RES + LS +
Sbjct: 1048 MPSSETGVTDPPLHELWYHGKMSRREAEKLL----GKDGDFLVRESGHNXSQFVLSGK-- 1209
Query: 193 DDMKGDHVKHYKIRKLDNGGYYITTRAQFETLQQLVQHY 231
H + + +D G T F+ + LV ++
Sbjct: 1210 -----HHGQFIHLLLVDPDGIVRTKDYIFDNISHLVSYH 1311
>31789
Length = 676
Score = 36.2 bits (82), Expect = 0.033, Method: Compositional matrix adjust.
Identities = 32/121 (26%), Positives = 58/121 (47%), Gaps = 11/121 (9%)
Frame = +2
Query: 266 RSLCLEKKLGQGCFAEVWLGTWNGNTKVAI-----KTLKPGTMSPESFLEEAQIMKKLKH 320
R L + ++G+G F V+ G + VA+ + K + F EEA+++K+L+H
Sbjct: 320 RFLKFDVEIGRGSFKTVYKGL-DTELGVAVAWCELQDKKWNKTERQRFKEEAEMLKELQH 496
Query: 321 DKLVQLYAVVSE------EPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAG 374
+V+ + E + I +VTE M G+L +LK + + L L + Q+ G
Sbjct: 497 PNIVRFFDYWEEHNHRNRKVIILVTELMTSGTLKTYLK--RFKKINLKVLKNWCRQILKG 670
Query: 375 M 375
+
Sbjct: 671 L 673
>21433
Length = 590
Score = 35.8 bits (81), Expect = 0.047, Method: Compositional matrix adjust.
Identities = 25/89 (28%), Positives = 40/89 (44%)
Frame = +2
Query: 370 QVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKW 429
Q+++ + Y IHRD++ N+L+G KIADFG + + T G + +
Sbjct: 191 QLSSALEYCHYRKVIHRDIKPENLLLGLKGDLKIADFGWSVHAPSSRRTTMCGT---LDY 361
Query: 430 TAPEAALYGRFTIKSDVWSFGILLTELVT 458
PE D+WS G+L E +
Sbjct: 362 LPPEMVEGKTHDENVDLWSLGVLCYEFLV 448
>01392
Length = 1806
Score = 35.8 bits (81), Expect = 0.048, Method: Compositional matrix adjust.
Identities = 32/109 (29%), Positives = 51/109 (46%), Gaps = 12/109 (11%)
Frame = -1
Query: 370 QVAAGMAYIERMNYIHRDLRSANIL---VGNGLICKIADFGLARLIE-DNEYTARQGAKF 425
+A + ++ HRDL+ NIL + + + KI DF LA I D + T
Sbjct: 1767 HIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGISCDGDGTKTPELLT 1588
Query: 426 PI---KWTAPEA--ALYG---RFTIKSDVWSFGILLTELVTKGRVPYPG 466
P+ ++ APE A G + + D+WS GI+L ++ G P+ G
Sbjct: 1587 PVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILYIMLC-GYPPFYG 1444
>18881
Length = 762
Score = 35.4 bits (80), Expect = 0.058, Method: Compositional matrix adjust.
Identities = 22/67 (32%), Positives = 35/67 (52%), Gaps = 2/67 (2%)
Frame = -3
Query: 169 PRGTFLIRESETTKGAYSLSIRDWDDMK--GDHVKHYKIRKLDNGGYYITTRAQFETLQQ 226
P GTFLIR + T S R+ + V+H K+ + G +Y+ F+++QQ
Sbjct: 748 PDGTFLIRVTNT-------SARESCPQY*YANAVRHIKVNRNPQGRFYLADGHYFDSVQQ 590
Query: 227 LVQHYSE 233
LV+HY +
Sbjct: 589 LVEHYEK 569
Score = 28.9 bits (63), Expect = 5.9, Method: Compositional matrix adjust.
Identities = 14/45 (31%), Positives = 22/45 (48%), Gaps = 2/45 (4%)
Frame = -3
Query: 101 LSFHKGEKFQIL--NSSEGDWWEARSLTTGETGYIPSNYVAPVDS 143
++ ++ IL N + WW+ +L T + GY P YV DS
Sbjct: 436 VTLKLNDRISILSKNGQDKGWWKGENLRTKKVGYFPLAYVDEEDS 302
>07933
Length = 728
Score = 35.0 bits (79), Expect = 0.070, Method: Compositional matrix adjust.
Identities = 13/30 (43%), Positives = 18/30 (60%)
Frame = +3
Query: 485 PQDCPISLHELMIHCWKKDPEERPTFEYLQ 514
P CP L+ +M+ CW +P RPTF L+
Sbjct: 3 PNYCPNLLYNIMMQCWSAEPSARPTFHKLE 92
>13664
Length = 507
Score = 35.0 bits (79), Expect = 0.071, Method: Compositional matrix adjust.
Identities = 16/45 (35%), Positives = 25/45 (55%)
Frame = +2
Query: 88 VALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGY 132
VALYDY+A+ D+L+ G+ +L+ WW L G+ G+
Sbjct: 374 VALYDYKAQRSDELTILSGDVIMLLHKDSESWWMGE-LLDGQQGF 505
>02638
Length = 1490
Score = 34.3 bits (77), Expect = 0.14, Method: Compositional matrix adjust.
Identities = 25/103 (24%), Positives = 49/103 (47%), Gaps = 7/103 (6%)
Frame = +1
Query: 427 IKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRM---- 482
I + APE + DVWS G ++ E+ T R P+ N+ ++ + +++
Sbjct: 28 IAFMAPEVLRGESYGRACDVWSVGCVMIEMCT-CRPPW---NSHDISNHLALIFKIASSV 195
Query: 483 ---PCPQDCPISLHELMIHCWKKDPEERPTFEYLQSFLEDYFT 522
P P++ + +LM+ C ++D + RP+ + L + FT
Sbjct: 196 DPPPIPENMSPPVRDLMLRCLEQDSDFRPSAKDL--LMHPLFT 318
>37260
Length = 401
Score = 33.9 bits (76), Expect = 0.18, Method: Composition-based stats.
Identities = 17/56 (30%), Positives = 30/56 (53%)
Frame = -1
Query: 149 WYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDWDDMKGDHVKHYK 204
WY+G L ++AE +L+ G+FL+R+S SLS + + ++H+K
Sbjct: 182 WYWGPLSYEEAESKLMD--KRDGSFLVRDSSNENYILSLSFKSMGHVHHTRIEHHK 21
>29360
Length = 363
Score = 33.9 bits (76), Expect = 0.19, Method: Composition-based stats.
Identities = 28/116 (24%), Positives = 50/116 (43%), Gaps = 7/116 (6%)
Frame = +3
Query: 287 WNGNTK--VAIKTLKPGTMSPESFLEEAQIMKKLKHD-----KLVQLYAVVSEEPIYIVT 339
W T VAIK LK E I+++L + V+ + + +
Sbjct: 12 WKKGTSEIVAIKILKNHPSYARQGQIEVSILQRLSQESADDYNFVRAFECFQHKNHTCLV 191
Query: 340 EYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILV 395
M + +L DFLK + + L L + + QV + ++++ IH DL+ NI++
Sbjct: 192 FEMLEQNLYDFLKQNKFQPLPLKYIRPITQQVLTALRKLKQLGLIHADLKPENIML 359
>24983
Length = 433
Score = 32.0 bits (71), Expect = 0.58, Method: Composition-based stats.
Identities = 17/53 (32%), Positives = 25/53 (47%), Gaps = 6/53 (11%)
Frame = +2
Query: 238 LCFNLTVIASSCTPQTSGLAKDAWEVA------RRSLCLEKKLGQGCFAEVWL 284
+C ++ ASS +P S ++ W V RRS C+ + LG E WL
Sbjct: 203 VCLSVMTTASSMSPNLSKYSRKLWSVV**GXPPRRSWCM*ELLGASDVCERWL 361
>17516
Length = 453
Score = 31.2 bits (69), Expect = 1.1, Method: Compositional matrix adjust.
Identities = 28/101 (27%), Positives = 47/101 (46%), Gaps = 6/101 (5%)
Frame = -3
Query: 431 APEAALY-GRFTIKSDVWSFGILLTELVTKGRVPYPGMNNR---EVLEQVERGYRMPCPQ 486
APE L G++ +K+DV+S I+L EL G+ +++ + + V+ G R
Sbjct: 415 APEVLLQKGQYDMKADVYSLAIILWEL-WYGQDAADHISSHLFGRLEDAVQAGLRPSVTM 239
Query: 487 DC--PISLHELMIHCWKKDPEERPTFEYLQSFLEDYFTATE 525
C P +L+ W+ +RPT F ED+ T+
Sbjct: 238 TCKPPDDWLKLLQSGWEFHASKRPTSRDAAEFFEDFLERTK 116
>18401
Length = 463
Score = 30.8 bits (68), Expect = 1.3, Method: Compositional matrix adjust.
Identities = 21/59 (35%), Positives = 30/59 (50%), Gaps = 5/59 (8%)
Frame = -3
Query: 429 WTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVER-----GYRM 482
+ APE L ++ DVWS G ++ EL T G + +N+E L +ER YRM
Sbjct: 434 YRAPEVILELGWSHPCDVWSVGCIMFELYT-GYTLFQTHDNKEHLAMMERILGSLPYRM 261
>13641
Length = 2081
Score = 30.8 bits (68), Expect = 1.3, Method: Compositional matrix adjust.
Identities = 15/58 (25%), Positives = 28/58 (48%), Gaps = 9/58 (15%)
Frame = +2
Query: 89 ALYDYEARTEDD-------LSFHKGEKFQILNSSEGDWWEA--RSLTTGETGYIPSNY 137
A++ + ++ +D+ LSF +G+ I+N + WW+A G IPS +
Sbjct: 164 AMFSFNSKLDDNIPCKEAGLSFQQGDILHIVNQEDAIWWQAYKHGDAKKRAGLIPSRH 337
>23319
Length = 2235
Score = 30.8 bits (68), Expect = 1.5, Method: Compositional matrix adjust.
Identities = 12/45 (26%), Positives = 24/45 (53%)
Frame = +3
Query: 432 PEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQV 476
P+ ++ D+WS G + EL GR +PG ++ + L+++
Sbjct: 3 PDVYXAKMYSTSIDMWSAGCIFAELANAGRPLFPGNDDDDQLKRI 137
>27287
Length = 514
Score = 30.8 bits (68), Expect = 1.5, Method: Compositional matrix adjust.
Identities = 11/30 (36%), Positives = 19/30 (63%)
Frame = -2
Query: 495 LMIHCWKKDPEERPTFEYLQSFLEDYFTAT 524
+M CW++DP +RP+F L L+ T++
Sbjct: 474 IMHSCWQEDPNDRPSFSRLVQELDKMLTSS 385
>29590
Length = 320
Score = 30.0 bits (66), Expect = 2.4, Method: Composition-based stats.
Identities = 13/43 (30%), Positives = 26/43 (60%)
Frame = +3
Query: 429 WTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNRE 471
+ APE Y +I++D+WS G+L ++T P+ G+ +++
Sbjct: 72 YVAPEVLDYEPLSIQTDMWSLGVLSYVMLTACS-PFVGITSKK 197
>36481
Length = 806
Score = 30.0 bits (66), Expect = 2.8, Method: Compositional matrix adjust.
Identities = 26/108 (24%), Positives = 48/108 (44%), Gaps = 6/108 (5%)
Frame = +2
Query: 293 VAIKTLKPGTMSPESFLEEAQIMKKLK----HDK--LVQLYAVVSEEPIYIVTEYMNKGS 346
+A+K +K E+ E +++KL+ H K VQ+ ++ +M S
Sbjct: 446 IALKIIKNVDKYREAAKLEINVLEKLREKDPHAKHMCVQMLDWFDYHGHVCISFHMLGLS 625
Query: 347 LLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANIL 394
+ DFLKD A + + ++ Q+ + ++ H DL+ NIL
Sbjct: 626 VFDFLKDNSYGAYPIEQVRHISYQLCYAVNFLHENQLTHTDLKPENIL 769
>27562
Length = 399
Score = 29.3 bits (64), Expect = 4.2, Method: Composition-based stats.
Identities = 18/54 (33%), Positives = 26/54 (48%), Gaps = 3/54 (5%)
Frame = -1
Query: 470 REVLEQVERGYRMPCPQDCPISLHELMIH-CWKKDPEERPT--FEYLQSFLEDY 520
R + Q+ R P+ C SL E++ WKKDP ER E L F++ +
Sbjct: 222 RVLWTQMRRRGTQIQPRPCSSSLFEIL*ETAWKKDPSERTENDIEILMDFMQHF 61
>18663
Length = 600
Score = 28.5 bits (62), Expect = 7.5, Method: Compositional matrix adjust.
Identities = 21/88 (23%), Positives = 36/88 (40%), Gaps = 8/88 (9%)
Frame = +2
Query: 428 KWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPY--------PGMNNREVLEQVERG 479
+ APE + D W+ G+LL E++ GR P+ P N + L QV
Sbjct: 23 NYIAPEILRGEDYGFSVDWWALGVLLYEMLA-GRSPFDIAGASENPDQNTEDYLFQVILE 199
Query: 480 YRMPCPQDCPISLHELMIHCWKKDPEER 507
+ P+ + ++ K+P +R
Sbjct: 200 KTIRIPRSLSVKAASVLKGFLNKNPADR 283
>15741
Length = 402
Score = 28.5 bits (62), Expect = 8.0, Method: Composition-based stats.
Identities = 11/32 (34%), Positives = 18/32 (56%)
Frame = -3
Query: 363 NLVDMAAQVAAGMAYIERMNYIHRDLRSANIL 394
+ A VA GMA++ +HRD+ + N+L
Sbjct: 97 DFFSFALHVARGMAHVANNKIVHRDVAARNVL 2
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000357656 | hsapiens_gene_ensembl | Proto-oncogene
tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn) (Protooncogene
Syn) (SLK). [Source:Uniprot/SWISSPROT;Acc:P06241]
(537 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
21808 317 1e-87
06405 305 4e-83
11780 196 6e-70
09007 156 2e-38
04852 148 7e-36
17300 122 3e-33
14116 126 3e-29
20640 125 6e-29
07291 122 3e-28
07940 109 3e-24
08294 104 9e-23
18996 98 7e-21
22005 82 3e-20
01718 93 3e-19
17637 93 3e-19
13592 91 9e-19
14477 90 2e-18
19301 89 3e-18
13305 80 3e-15
01756 77 2e-14
00715 77 3e-14
12721 75 8e-14
18921 72 4e-13
01707 70 1e-12
17253 70 3e-12
01060 69 3e-12
00300 68 1e-11
14126 66 3e-11
29581 66 3e-11
18484 63 2e-10
25550 63 3e-10
14420 62 7e-10
27546 61 1e-09
04591 61 1e-09
00392 59 6e-09
11228 58 8e-09
01966 58 8e-09
09606 58 1e-08
03240 57 2e-08
31885 57 2e-08
07836 57 2e-08
13066 56 3e-08
12672 54 2e-07
13212 53 3e-07
04138 52 5e-07
21079 52 8e-07
29243 51 1e-06
12324 49 5e-06
19094 49 7e-06
30755 48 1e-05
15910 48 1e-05
26560 47 3e-05
21210 46 5e-05
14257 45 6e-05
19761 45 7e-05
29687 45 8e-05
11185 44 1e-04
16708 42 4e-04
28638 42 6e-04
28095 42 8e-04
26711 41 0.001
12786 41 0.001
05206 41 0.001
01494 40 0.002
37602 40 0.002
06462 40 0.002
32000 40 0.003
18481 40 0.003
32264 39 0.004
35671 39 0.007
16716 38 0.012
17286 37 0.014
27405 37 0.014
30740 37 0.017
38046 37 0.023
21433 36 0.044
18881 35 0.060
01392 35 0.061
00394 35 0.063
07933 35 0.070
13664 35 0.078
36481 35 0.082
02638 34 0.15
31789 34 0.17
37260 34 0.17
29360 34 0.19
32359 32 0.76
32357 32 0.86
17516 32 0.90
18401 31 1.2
13641 31 1.3
23319 31 1.3
27287 31 1.5
29590 30 2.1
27562 29 3.9
18663 28 6.6
15741 28 8.0
32465 28 9.0
>21808
Length = 1011
Score = 317 bits (813), Expect(2) = 1e-87, Method: Compositional matrix adjust.
Identities = 152/225 (67%), Positives = 180/225 (80%), Gaps = 1/225 (0%)
Frame = +1
Query: 288 GTWNGNTKVAIKTLKPGTMSPESFLEEAQIMKKLKHDKLVQLYAVVSEE-PIYIVTEYMN 346
G WN T VAIKTLK GTM P+ FL EAQIMKKL+H KL+QLYAV +++ PI+I+TE M
Sbjct: 4 GLWNNTTPVAIKTLKSGTMDPKDFLAEAQIMKKLRHPKLIQLYAVCTQDDPIFIITELMK 183
Query: 347 KGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKI 406
GSLL+FL+ G+GR LKLP L+D+ AQ+A GMAY+E NYIHRDL + NILV + KI
Sbjct: 184 NGSLLEFLQ-GKGRVLKLPALIDIGAQIACGMAYLESQNYIHRDLAARNILVSDNNTVKI 360
Query: 407 ADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVP 466
ADFGLAR+I+++EY AR GA+FPIKWTAPEAA Y RFTIKSDVWSFGILLTE VT GRVP
Sbjct: 361 ADFGLARVIKEDEYEARVGARFPIKWTAPEAANYNRFTIKSDVWSFGILLTETVTYGRVP 540
Query: 467 YPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKKDPEERP 511
YPGM N EVL QVE GYRMPCP CP L+++M+ CW+K+ ERP
Sbjct: 541 YPGMTNAEVLHQVEHGYRMPCPPGCPKPLYDIMLECWRKEEMERP 675
Score = 24.6 bits (52), Expect(2) = 1e-87, Method: Compositional matrix adjust.
Identities = 11/22 (50%), Positives = 14/22 (63%)
Frame = +2
Query: 511 PTFEYLQSFLEDYFTATEPQYQ 532
PTFE LQ LE++FT Y+
Sbjct: 674 PTFETLQWKLEEFFTMDSKDYR 739
>06405
Length = 1965
Score = 305 bits (780), Expect = 4e-83, Method: Compositional matrix adjust.
Identities = 164/351 (46%), Positives = 224/351 (63%), Gaps = 3/351 (0%)
Frame = +1
Query: 177 ESETTKGAYSLSIRDWDDMKGDHVKHYKIRKLDNGGYYITTRAQFETLQQLVQHYSERAA 236
ESE++ G S+S+R +G V HY+I + D+G ++T +F TL +LV H+S A
Sbjct: 1 ESESSPGQRSISVR----FEG-RVYHYRITE-DDGKVFVTQEHRFNTLAELVHHHSIHAD 162
Query: 237 GLCCRLVVPCHKGM-PRLTDLSVKTKDVWEIPRESLQLIKRLGNGQFGEVWMGTWNG-NT 294
GL L+ P K P + +S + D WEI R + + RLG GQ+G+V+ W N
Sbjct: 163 GLVTTLLYPAPKRQKPTVFGVSPEP-DRWEIERTEIAMKHRLGGGQYGDVYEAMWKRYNK 339
Query: 295 KVAIKTLKPGTMSPESFLEEAQIMKKLKHDKLVQLYAVVSEEP-IYIVTEYMNKGSLLDF 353
VA+KTLK TM+ FLEEA IMK++KH LVQL V + EP YIVTE+M G+LLD+
Sbjct: 340 IVAVKTLKEDTMALNDFLEEAAIMKEMKHPNLVQLLGVCTREPPFYIVTEFMPHGNLLDY 519
Query: 354 LKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLAR 413
L+ L+ MA Q+A+GMAY+E N+IHRDL + N LV + + K+ADFGLAR
Sbjct: 520 LRSSTREENGPTALMYMATQIASGMAYLETKNFIHRDLAARNCLVADSNMVKVADFGLAR 699
Query: 414 LIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNR 473
L++D+ YTA GAKFPIKWTAPE + RF+ +SD+W+FG+LL EL T G PYPG+
Sbjct: 700 LMKDDTYTAHIGAKFPIKWTAPEGLAFNRFSTRSDIWAFGVLLWELATYGMSPYPGVELT 879
Query: 474 EVLEQVERGYRMPCPQDCPISLHELMIHCWKKDPEERPTFEYLQSFLEDYF 524
EV +ERGYRM P P ++ LM+ CW+ DP++RPTF+ + LE+ F
Sbjct: 880 EVYHLLERGYRMERPPGTPADVYILMLKCWQWDPKDRPTFKEIHFLLENMF 1032
>11780
Length = 1713
Score = 196 bits (498), Expect(2) = 6e-70, Method: Compositional matrix adjust.
Identities = 123/341 (36%), Positives = 181/341 (53%), Gaps = 6/341 (1%)
Frame = +3
Query: 103 FHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYVAP--VDSIQAEEWYFGKLGRKDAE 160
F KG+ I ++ W + G G IP+NYV P V ++ A W+ GK+ R+ AE
Sbjct: 111 FQKGDLLVIRRATSDRMWYKACDSNGREGMIPANYVQPRKVVTLHAMPWFHGKITRQQAE 290
Query: 161 RQLLSFGNPR--GTFLIRESETTKGAYSLSIRDWDDMKGDHVKHYKIRKLDNGGYYITTR 218
L PR G FLIRES G Y+L + V+HY+I +N I
Sbjct: 291 ELL----KPREDGLFLIRESSNYPGDYTLCV-----CHLGKVEHYRILYRENQ-LTIDEE 440
Query: 219 AQFETLQQLVQHYSERAAGLCCRLVVPCHKGMPRLTDLSVK--TKDVWEIPRESLQLIKR 276
F L +LV+HY A GLC +L P K +S++ W I + L++ +
Sbjct: 441 GFFRNLDELVKHYLADADGLCTQLTRPVTKQGGNFGTVSLQEFKSGGWVIAXQDLEIGEA 620
Query: 277 LGNGQFGEVWMGTWNGNTKVAIKTLKPGTMSPESFLEEAQIMKKLKHDKLVQLYAVVSEE 336
+G G FG+V+ G + G VAIK LK +SFL+EA +M L+HD LV+L VV E
Sbjct: 621 IGKGDFGDVYKGMYRGQP-VAIKQLKDKDRGEQSFLQEASVMTSLRHDNLVRLIGVVLGE 797
Query: 337 PIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANI 396
I++VTE+M KG+L+++L+ + + ++ A A M Y+E +HRDL + N+
Sbjct: 798 TIFLVTEFMGKGNLVEYLRSRGRSVITKKDQINFATDTCAAMEYLESKRLVHRDLAARNV 977
Query: 397 LVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEA 437
LV + K++DFGLA+ + ++ + KFPIKWTAPEA
Sbjct: 978 LVHDDGKAKVSDFGLAKFGDFSQTS----VKFPIKWTAPEA 1088
Score = 86.7 bits (213), Expect(2) = 6e-70, Method: Compositional matrix adjust.
Identities = 41/86 (47%), Positives = 57/86 (66%)
Frame = +1
Query: 442 RFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIH 501
+FT KSD+WSFGILL E+ + GRVPYP + +V+ VERGYRM P+ CP ++ +M
Sbjct: 1102 KFTSKSDMWSFGILLWEIYSFGRVPYPRIPLTDVVMHVERGYRMEAPEGCPPEIYSIMKQ 1281
Query: 502 CWKKDPEERPTFEYLQSFLEDYFTAT 527
W+ DP ERPTF+ + + L + T
Sbjct: 1282 AWELDPNERPTFKSVLARLNNQRAVT 1359
>09007
Length = 1440
Score = 156 bits (394), Expect = 2e-38, Method: Compositional matrix adjust.
Identities = 98/283 (34%), Positives = 151/283 (53%), Gaps = 15/283 (5%)
Frame = -1
Query: 266 IPRESLQLIKRLGNGQFGEVWMGTWNGNT----KVAIKTLKPGTMSP--ESFLEEAQIMK 319
I ++ + L K LG G FG V W + +VA+K L + + FL+E IM+
Sbjct: 888 ISKDCVALSKSLGQGHFGTVRQAIWTAESGEKVQVAVKCLSKDKIHKDGQEFLKETAIMQ 709
Query: 320 KLKHDKLVQLYAVVSEE--PIYIVTEYMNKGSLLDFLKDGEGRA-LKLPNLVDMAAQVAA 376
L H+ +V++Y VV + I +VTE SLL+ +K+ R +P L D + QV
Sbjct: 708 MLDHENIVRVYGVVMDNGADIMLVTELAPMRSLLECVKEVSARVDFSVPRLCDFSQQVCD 529
Query: 377 GMAYIERMNYIHRDLRSANILVGNGLICKIADFGLA-RLIEDNEYTARQGA---KFPIKW 432
GM+Y+E +HRDL + NIL+ + KI+D G++ L EY Q + + W
Sbjct: 528 GMSYLESKRLVHRDLAARNILLFSKSKVKISDVGVSGALGAGKEYYQSQQTIHLQNAVAW 349
Query: 433 TAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVE--RGYRMPCPQD 490
APE+ F+ SDVW+FG+LL E T G P+ G+N ++++E V+ + R+ P
Sbjct: 348 CAPESFRNLCFSSASDVWAFGVLLWEFFTHGFQPWAGLNGQQIMEAVDAPQSQRLEQPDL 169
Query: 491 CPISLHELMIHCWKKDPEERPTFEYLQSFLEDYFTATEPQYQP 533
CP + +M+ CW+++P+ RPTF L FL T PQ +P
Sbjct: 168 CPKEYYAVMLKCWEQEPQRRPTFSQL--FL------TLPQIRP 64
>04852
Length = 1462
Score = 148 bits (373), Expect = 7e-36, Method: Compositional matrix adjust.
Identities = 87/259 (33%), Positives = 136/259 (52%), Gaps = 31/259 (11%)
Frame = +1
Query: 294 TKVAIKTLKPGTMSPE--SFLEEAQIMKKLK----HDKLVQLYAVVSEE-PIYIVTEYMN 346
+ VA+K L+ + E F++E Q+MK +K H +V ++ P++++ E+
Sbjct: 22 STVAVKMLRDIVTAVEEQDFVQELQVMKAVKKMGSHINIVNFLGCCTQGGPLWVIVEFAK 201
Query: 347 KGSLLDFL---KDG--------------------EGRALKLPNLVDMAAQVAAGMAYIER 383
G+L DFL +DG G ++ NL+ A Q+A GM ++
Sbjct: 202 NGNLRDFLESCRDGINGYGKFVSPQDPGWYTKTPGGHVIRRKNLLSYAFQIARGMEFLAS 381
Query: 384 MNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRF 443
IHRDL + N+LV + KIADFGL+R + Y R G + P+KW APEA R+
Sbjct: 382 RKCIHRDLAARNVLVTEEHVLKIADFGLSR--TGDYYKKRSGGRLPVKWMAPEALFDMRY 555
Query: 444 TIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQ-VERGYRMPCPQDCPISLHELMIHC 502
T KSDVWSFG++L E+ + G +PY + N E+ + ++ YRMP P+ +L+ +M C
Sbjct: 556 TTKSDVWSFGVVLWEIFSLGGMPYASIPNEELYSKLLDDAYRMPRPELASGNLYAIMERC 735
Query: 503 WKKDPEERPTFEYLQSFLE 521
W P +RP F L ++
Sbjct: 736 WLNRPSDRPEFSQLVGHID 792
>17300
Length = 480
Score = 122 bits (307), Expect(2) = 3e-33, Method: Compositional matrix adjust.
Identities = 56/117 (47%), Positives = 83/117 (70%), Gaps = 4/117 (3%)
Frame = +1
Query: 374 VAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDN----EYTARQGAKFP 429
+++GM + M Y+HRDL + NILV L+CK+ADFGL+R IE + YT + G K P
Sbjct: 1 ISSGMGXLADMGYVHRDLAARNILVNEILVCKVADFGLSREIESDTTEGAYTTK-GGKIP 177
Query: 430 IKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMP 486
++WTAPEA Y +FT SDVWSFG+++ E+++ G PY +N++V++ VE+GYR+P
Sbjct: 178 VRWTAPEAIAYRKFTSASDVWSFGVVMWEVMSYGERPYWNWSNQDVIKAVEKGYRLP 348
Score = 37.7 bits (86), Expect(2) = 3e-33, Method: Composition-based stats.
Identities = 16/43 (37%), Positives = 23/43 (53%), Gaps = 1/43 (2%)
Frame = +2
Query: 487 CPQ-DCPISLHELMIHCWKKDPEERPTFEYLQSFLEDYFTATE 528
CP DCP +LH+LM+ W+K+ RP + L+ A E
Sbjct: 344 CPSMDCPEALHQLMLDAWQKERSHRPKMSMVVKTLDKLIRAPE 472
>14116
Length = 1017
Score = 126 bits (316), Expect = 3e-29, Method: Compositional matrix adjust.
Identities = 75/216 (34%), Positives = 120/216 (55%), Gaps = 13/216 (6%)
Frame = -1
Query: 266 IPRESLQLIKRLGNGQFGEVWMGTWN-----GNTKVAIKTL---KPGTMSPESFLEEAQI 317
I RE L + + +G G FG V G G+ VA+KTL P + +SFL+EA I
Sbjct: 645 IDREFLTMGEEIGKGNFGCVKRGFLTLPEQKGDILVAVKTLHNNNPREIELQSFLQEALI 466
Query: 318 MKKLKHDKLVQLYAV---VSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQV 374
MK H ++ L + + + P+ +V +M G LL +++D + + + +L+ +
Sbjct: 465 MKDFHHSNVLTLIGICLNLDDMPL-VVLPFMKHGDLLTYIRDDQHQP-TIKDLIMYGVDI 292
Query: 375 AAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQG--AKFPIKW 432
A GM Y+ + ++HRDL + N ++ K+ADFGLAR I + EY + + AK P+KW
Sbjct: 291 ARGMDYLAGLKFVHRDLAARNCMLDEDFHVKVADFGLARDIYEKEYYSSENKKAKLPVKW 112
Query: 433 TAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYP 468
A E+ G + K+DVWS+G++L EL+T+G P
Sbjct: 111 MALESLEKGNYDSKTDVWSYGVVLWELLTRGSDALP 4
>20640
Length = 1492
Score = 125 bits (313), Expect = 6e-29, Method: Compositional matrix adjust.
Identities = 59/144 (40%), Positives = 86/144 (59%), Gaps = 1/144 (0%)
Frame = +1
Query: 386 YIHRDLRSANILVGNGLICKIADFGLARLIED-NEYTARQGAKFPIKWTAPEAALYGRFT 444
Y+HRDL + N LVG+ L+ KI+DFGLAR + + Y + PI+W EA LY +F+
Sbjct: 7 YVHRDLATRNCLVGHDLVVKISDFGLARSVHSVDYYRGSEHDAIPIRWMPLEAILYNKFS 186
Query: 445 IKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWK 504
+SDVWSFG++L E+ PY G+ + EV+ V+ G + CP+ P ++ELM CW
Sbjct: 187 TQSDVWSFGVVLWEIFAFALQPYYGLTHEEVVRFVKEGKVLACPERTPPPMYELMKQCWH 366
Query: 505 KDPEERPTFEYLQSFLEDYFTATE 528
+ P RP+F L LE+ + E
Sbjct: 367 RRPATRPSFHTLHKTLENMHSKYE 438
>07291
Length = 833
Score = 122 bits (306), Expect = 3e-28, Method: Compositional matrix adjust.
Identities = 60/167 (35%), Positives = 98/167 (58%), Gaps = 2/167 (1%)
Frame = +1
Query: 359 GRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLA-RLIED 417
+ L + L+D Q+A GMAY++ + +HR+L + N +V +++D+G+ L
Sbjct: 31 SKMLTVVQLLDFGRQIADGMAYLQEVKVVHRNLAARNCIVTEDGRLQLSDYGVTGSLFPQ 210
Query: 418 NEYTARQG-AKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVL 476
+ YTA A+ +KW APE F+ KSDVW+FG++L EL+T+G PYP + N +L
Sbjct: 211 SYYTADDSPARDLVKWMAPETIDNFHFSSKSDVWAFGVVLWELLTRGITPYPDVENSSLL 390
Query: 477 EQVERGYRMPCPQDCPISLHELMIHCWKKDPEERPTFEYLQSFLEDY 523
++ G+RM P+ P ++E+M CW + PE+RP F L L+ +
Sbjct: 391 PYLKEGHRMKKPKQSPEPVYEMMTACWNESPEQRPDFAELNDQLKTF 531
>07940
Length = 1336
Score = 109 bits (272), Expect = 3e-24, Method: Compositional matrix adjust.
Identities = 87/286 (30%), Positives = 125/286 (43%), Gaps = 70/286 (24%)
Frame = -3
Query: 255 DLSVKTKDVWEIPRESLQLIKRLGNGQFGEVW----MGTW--NGNTKVAIKTLKPGTMSP 308
DL + K WE PRE L L RLG G FG V MG + N + VA+K LK
Sbjct: 878 DLPLDAK--WEFPRERLVLGDRLGEGAFGLVMKGEAMGIFKDNNSVTVAVKMLKEDATDR 705
Query: 309 E--SFLEEAQIMKKL-KHDKLVQ----------LYAVVSEEPIYIVTEYMN--------- 346
E + E ++MK + KH ++ LY +V P + +++
Sbjct: 704 EMMDLIREMEMMKVIGKHKNIINLLGCCTQRGALYVIVEFAPHGNLRDFLKSHRPHGTSY 525
Query: 347 ----------------------------KGSLLDFL-------------KDGEGRALKLP 365
+G+ L F+ + + L
Sbjct: 524 SCIADYEQPVITSSSSSFSHPNSASSSAQGTSLGFIPGTSTVSFSTGSHRQDMLKMLTPK 345
Query: 366 NLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQ- 424
+L+ A QVA GM Y+ IHRDL + N+LV + KIADFGL R ++ +Y +
Sbjct: 344 DLISYAYQVARGMEYLASKQCIHRDLAARNVLVAEEYVLKIADFGLTRNLQQFDYYRKTT 165
Query: 425 GAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGM 470
+ P+KW APEA ++T KSDVWS+G+LL E+ T G PYP +
Sbjct: 164 DGRLPVKWMAPEALFDRKYTSKSDVWSYGVLLWEIFTLGGNPYPSV 27
>08294
Length = 1849
Score = 104 bits (260), Expect = 9e-23, Method: Compositional matrix adjust.
Identities = 64/207 (30%), Positives = 100/207 (48%), Gaps = 11/207 (5%)
Frame = +2
Query: 325 KLVQLYAVVSE-EPIYIVTEYMNKGSLLDFL-----KDGEGRALKLPNL-----VDMAAQ 373
+V V E EP +++TEY + G L FL +G GR ++P L + M Q
Sbjct: 890 NIVHFMGVCREAEPHFLITEYCDWGDLKQFLLATRNDNGRGRGTRVPALALSQKLGMGQQ 1069
Query: 374 VAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWT 433
VAAGM + +H DL + N+L+ + + K+A L+ + +EY P++W
Sbjct: 1070 VAAGMEALSNQGLVHGDLAARNVLLTSRMQLKVARPALSGDVYASEYYPLHQRLVPLRWL 1249
Query: 434 APEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPI 493
PE L T DVW+FG+ L E++ +PY M++ EVL ++ D P
Sbjct: 1250 PPEGVLEDSATTCGDVWAFGVFLWEVLQLADLPYRLMSDEEVLRSLQHSQAALDSPDAPP 1429
Query: 494 SLHELMIHCWKKDPEERPTFEYLQSFL 520
+L L+ C + P +RP F + S L
Sbjct: 1430 ALLSLLQRCTAQQPSQRPPFSEICSVL 1510
>18996
Length = 491
Score = 98.2 bits (243), Expect = 7e-21, Method: Compositional matrix adjust.
Identities = 55/136 (40%), Positives = 79/136 (58%), Gaps = 6/136 (4%)
Frame = +2
Query: 387 IHRDLRSANILVGNGLICKIADFGLARLIE-DNEYTARQGAKFPIKWTAPEAALYGRFTI 445
IHRDL + NILV + KI+DFGLA+ D Y PIKW +PEA +F+
Sbjct: 2 IHRDLAARNILVDRSCV-KISDFGLAQFANADGYYYGISQRDIPIKWYSPEAIETCKFSS 178
Query: 446 KSDVWSFGILLTELVTKGRVP--YPG--MNNREVLEQVERGYRMPCPQDCPISLH-ELMI 500
SDVWS+G+ L E+ ++G +P PG + E L ++ +G R+P P+ C ++ ELM
Sbjct: 179 YSDVWSYGVTLFEMFSRGEIPNLLPGHDLTQEEFLNRLRKGERLPKPELCSDFVYSELMR 358
Query: 501 HCWKKDPEERPTFEYL 516
CW + P+ RPTF +
Sbjct: 359 PCWHEMPKSRPTFHQI 406
>22005
Length = 873
Score = 82.4 bits (202), Expect(2) = 3e-20, Method: Compositional matrix adjust.
Identities = 58/194 (29%), Positives = 91/194 (46%), Gaps = 44/194 (22%)
Frame = +1
Query: 311 FLEEAQIMKKLKHDKLVQLYAVVS-EEPIYIVTEYMNKGSLLDFLKDGEGRALKLP---- 365
F EA +M H +V+L V + +P+ ++ E+M+KG L DFL+ LP
Sbjct: 151 FEREASLMADFDHPNIVKLLGVCAIGKPMCLLFEFMSKGDLNDFLRLCSPENYNLPVSRS 330
Query: 366 -NLVD-------------------------------------MAAQVAAGMAYIERMNYI 387
NLV ++ Q++AGMAY+ + +Y+
Sbjct: 331 QNLVVDLEDGLRVEVEAEECEKDTQSEDRDCSGMLXTKDQLYISQQISAGMAYLAQKDYV 510
Query: 388 HRDLRSANILVGNGLICKIADFGLARLIEDNEY-TARQGAKFPIKWTAPEAALYGRFTIK 446
HRDL + + I+DFGLAR + +Y + PI+W EA LY +F+ +
Sbjct: 511 HRDL-ATRTVXSRTT*S*ISDFGLARSVHSVDYYRGSEQDAIPIRWMPLEAILYSKFSTQ 687
Query: 447 SDVWSFGILLTELV 460
SDVWSFG++L E++
Sbjct: 688 SDVWSFGVVLWEIL 729
Score = 34.3 bits (77), Expect(2) = 3e-20, Method: Compositional matrix adjust.
Identities = 15/42 (35%), Positives = 24/42 (57%)
Frame = +3
Query: 466 PYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKKDP 507
PY G+ + EV+ V+ G + P P ++ELM CW++ P
Sbjct: 744 PYYGLTHEEVVNYVKAGKILEQPTKTPHQVYELMKQCWQRRP 869
>01718
Length = 959
Score = 92.8 bits (229), Expect = 3e-19, Method: Compositional matrix adjust.
Identities = 80/268 (29%), Positives = 130/268 (48%), Gaps = 16/268 (5%)
Frame = +3
Query: 273 LIKRLGNGQFGEVWMGTWNGNTKVAIKTLKPGTMSPESFLEEAQIMKKLKHDKLVQLYAV 332
+ +++G G F EV+ T +V + T + + L E Q++ +L+H +++ V
Sbjct: 159 ICEKIGAGFFSEVFKVTHRITGQVMALKMNTMTSNRHNMLREVQLLNRLQHANILRFMGV 338
Query: 333 -VSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLP--NLVDMAAQVAAGMAYIERMNYIHR 389
V E ++ +TEY+ G+L L E + +LP + + +A G+ Y+ +IHR
Sbjct: 339 CVHEGQLHALTEYIPSGNLEQLL---EKKDEELPWTQRIQLTLGLARGLDYLHSTRFIHR 509
Query: 390 DLRSANILV----GNGLICKIADFGLARLIE---DNEYTARQGAKFPIKWTAPEAALYGR 442
DL S NIL+ +G IADFGLA I D E G+ + W APE L G
Sbjct: 510 DLTSKNILIRREDNHGYHAVIADFGLATKIPDPLDKEKLPTVGSPY---WMAPE-VLNGH 677
Query: 443 F-TIKSDVWSFGILLTELVTKGRVP-----YPGMNNREVLEQVERGYRMPCPQDCPISLH 496
F ++D++S GI++ E+ R+P P MNN V + V + CP+
Sbjct: 678 FYNERADLFSVGIIMCEIT--ARIPADPDIMPRMNNFGV-DYVALSEMI---SYCPLDYL 839
Query: 497 ELMIHCWKKDPEERPTFEYLQSFLEDYF 524
+L C + DP++RP + +LE F
Sbjct: 840 QLAFKCCQVDPQKRPRGVEIIEWLEKIF 923
>17637
Length = 447
Score = 92.8 bits (229), Expect = 3e-19, Method: Compositional matrix adjust.
Identities = 46/132 (34%), Positives = 74/132 (56%), Gaps = 1/132 (0%)
Frame = +1
Query: 395 NILVGNGLICKIADFGLARLIEDNEYTARQGAKF-PIKWTAPEAALYGRFTIKSDVWSFG 453
N ++ + L K+ D L+R + +Y ++ PIKW + EA + SDVWSFG
Sbjct: 1 NCVIDDQLRVKLTDSALSRDLFSGDYNCLGDGEYRPIKWLSLEALQKSHYNEGSDVWSFG 180
Query: 454 ILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKKDPEERPTF 513
+L+ E+ T G++PY ++ E+ ++ GYR+ P +CP L +M +CW P ERP+F
Sbjct: 181 VLMWEMCTLGKLPYAEIDPYEMEHYLKDGYRLAQPFNCPDELFTIMAYCWASMPAERPSF 360
Query: 514 EYLQSFLEDYFT 525
LQ L ++ T
Sbjct: 361 SQLQICLSEFHT 396
>13592
Length = 980
Score = 91.3 bits (225), Expect = 9e-19, Method: Compositional matrix adjust.
Identities = 68/252 (26%), Positives = 131/252 (51%), Gaps = 17/252 (6%)
Frame = +2
Query: 276 RLGNGQFGEVWMGTWNGNTKV-AIK--TLKPG-TMSPESFLEEAQIMKKLKHDKLVQLYA 331
++G G+FG+V+ N ++ A+K ++PG T + ++ EE +I++ +KH LV+ Y
Sbjct: 5 KIGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETRALKNVAEELKILEGIKHKNLVRYYG 184
Query: 332 V-VSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVD--MAAQVAAGMAYIERMNYIH 388
+ V E + I E ++G+L ++ G LP + AQ+ +G+A + + +H
Sbjct: 185 IEVHREELLIFMELCSEGTLESLVELTGG----LPEALSRRFTAQLLSGVAELHKHGIVH 352
Query: 389 RDLRSANILVGNGL-ICKIADFGLARLIEDNE--------YTARQGAKFPIKWTAPEAAL 439
RD+++ANI + +G K+ DFG A I+ + Y Q P +T +
Sbjct: 353 RDIKTANIFLVDGSNSLKLGDFGSAVKIQAHTTVPGELQGYVGTQAYMAPEVFTKTNSDG 532
Query: 440 YGRFTIKSDVWSFGILLTELVTKGRVPYPGMN-NREVLEQVERGYRMPCPQDCPISLHEL 498
+GR +D+WS G ++ E+ + G+ P+ + N +++ +V G + P+ H+
Sbjct: 533 HGRL---ADIWSVGCVVVEMAS-GKRPWAQFDSNFQIMFKVGMGEKPQAPESLSQEGHDF 700
Query: 499 MIHCWKKDPEER 510
+ HC + DP++R
Sbjct: 701 IDHCLQHDPKQR 736
>14477
Length = 493
Score = 90.1 bits (222), Expect = 2e-18, Method: Composition-based stats.
Identities = 56/166 (33%), Positives = 94/166 (56%), Gaps = 9/166 (5%)
Frame = -1
Query: 269 ESLQLIK-RLGNGQFGEVWMGTWNGNTK---VAIKTLKPGTMSPE---SFLEEAQIMKKL 321
E +Q+ + +LG G FG V G + + VAIK LK + P ++EA++MKK+
Sbjct: 493 EQIQMDELKLGAGNFGSVMKGVCRLDDREIPVAIKVLKNADLDPSVQSELIKEAEVMKKM 314
Query: 322 KHDKLVQLYAVVSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYI 381
H +V+L + E + +V E G L FL + + L L N++++ QV+ GM Y+
Sbjct: 313 DHMHIVRLIGLCEGETMMLVLELAKLGPLNKFLP--KNKHLPLWNILELMWQVSQGMEYL 140
Query: 382 ERMNYIHRDLRSANILVGNGLICKIADFGLARLI--EDNEYTARQG 425
E ++HRDL + NIL+ + KI+DFG+++ + E+N Y A++
Sbjct: 139 EANKFVHRDLAARNILLCDEHFAKISDFGMSKTLSRENNYYMAQEA 2
>19301
Length = 712
Score = 89.4 bits (220), Expect = 3e-18, Method: Compositional matrix adjust.
Identities = 54/156 (34%), Positives = 88/156 (56%), Gaps = 3/156 (1%)
Frame = +2
Query: 258 VKTKDVWEIPRESLQLIKRLGNGQFGEVWMGTWNGNTKVAIKTLKPGTMSPESFLEEAQI 317
+K +D WEIP ES+ ++ LG+G G V++G +VA+K ++ ++E I
Sbjct: 272 LKQQDDWEIPFESITDLEWLGSGAQGAVFLGKLCAE-EVAVKKVRD--------IKETDI 424
Query: 318 --MKKLKHDKLVQLYAVVSEEPIY-IVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQV 374
++KL H ++ V ++ P Y I+ EY G L + L+DG+ L ++D + Q+
Sbjct: 425 RNLRKLNHPNIISFKGVCTQAPCYCIIMEYCPYGQLYEVLRDGKEIPPAL--VLDWSKQI 598
Query: 375 AAGMAYIERMNYIHRDLRSANILVGNGLICKIADFG 410
A+GM Y+ IHRDL+S N+LV + KI+DFG
Sbjct: 599 ASGMNYLHSHKIIHRDLKSPNVLVAKNDVVKISDFG 706
>13305
Length = 549
Score = 79.7 bits (195), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 35/102 (34%), Positives = 59/102 (57%), Gaps = 4/102 (3%)
Frame = +2
Query: 425 GAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYR 484
+ PI+W A E+ +T +SDVWSFG++L E+ T G PY + +++ ++ GYR
Sbjct: 2 STRVPIRWMAVESLFNNTYTTQSDVWSFGVVLWEIFTLGGTPYSSTDTQQLFAFLKDGYR 181
Query: 485 MPCPQDCPISLHELMIHCWKKDPEERPTFE----YLQSFLED 522
+ P+ C + + +M+ CW ++ + RPTF LQ L+D
Sbjct: 182 LKRPKLCDQNTYAMMLQCWNENAQRRPTFPELCGRLQRMLDD 307
>01756
Length = 1858
Score = 77.0 bits (188), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 59/214 (27%), Positives = 95/214 (44%), Gaps = 22/214 (10%)
Frame = -3
Query: 274 IKRLGNGQFGEVWMGTWNGNTKVAIKTLKPGTMS------PESFLEEAQIMKKLKHDKLV 327
+ ++G G FGEV+ +V +K M P + L E +I++ L H+ +V
Sbjct: 1727 LAKIGQGTFGEVFKARCKKTKQVV--AMKKVLMDNEKEGFPITALREIKILQLLNHENVV 1554
Query: 328 QLYAVVSEEP---------IYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGM 378
L + S + Y+V E+ L L LP + ++ Q+ G+
Sbjct: 1553 DLIEICSTKATSANRYKSMFYLVFEFCEHD--LAGLLSNMSVVFNLPEIKEVMKQLMNGL 1380
Query: 379 AYIERMNYIHRDLRSANILVGNGLICKIADFGLAR-----LIEDNEYTARQGAKFPIKWT 433
YI R +HRD+++ANIL+ + K+ADFGLAR L + N YT R W
Sbjct: 1379 YYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNR----VVTLWY 1212
Query: 434 APEAALYG--RFTIKSDVWSFGILLTELVTKGRV 465
P L G ++ D W G ++ E+ T+ +
Sbjct: 1211 RPPELLLGDRNYSTAIDQWGAGCIMAEMWTRNPI 1110
>00715
Length = 1788
Score = 76.6 bits (187), Expect = 3e-14, Method: Compositional matrix adjust.
Identities = 62/223 (27%), Positives = 103/223 (46%), Gaps = 31/223 (13%)
Frame = +1
Query: 321 LKHDKLVQLYAVVS----EEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAA 376
L+H +V + S E+ ++ EY+ +L L D + + + + +A Q+A
Sbjct: 97 LRHVNVVSILGATSLHRFEDGAWLAMEYVGPLNLQTILNDHQ-QDIDSSMRLSLALQMAR 273
Query: 377 GMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLI----------------EDNEY 420
G+ Y+ +N +H DL+ AN L+ L +IADFG + + E
Sbjct: 274 GLHYLHSINIVHLDLKPANCLLTRDLKLRIADFGCCHQLTPTGLDMGEREGGMAGNELEL 453
Query: 421 TARQGA-----KFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREV 475
T QGA + + APE + +++SDV+S GI L ++ T+ + PY G+ V
Sbjct: 454 TPVQGAWKNELAGTLAYRAPELLKGLQPSVRSDVYSLGITLWQMCTR-QGPYEGVPAHAV 630
Query: 476 LEQVERGYRMPCP----QDCP--ISLHELMIHCWKKDPEERPT 512
+ QV PCP +D P + +L CW + E+RPT
Sbjct: 631 VYQVVSKDLRPCPPPSTEDDPFEVMFRDLYTQCWARRVEDRPT 759
>12721
Length = 821
Score = 74.7 bits (182), Expect = 8e-14, Method: Compositional matrix adjust.
Identities = 54/226 (23%), Positives = 103/226 (45%), Gaps = 3/226 (1%)
Frame = +1
Query: 267 PRESLQLIKRLGNGQFGEVWMGTWNGNTKVAIKTLKPGTMSPESFL-EEAQIMKKLKHDK 325
PR L ++G G G V + T ++A+K + L E +M+ H
Sbjct: 82 PRTFLDDFMKIGEGSTGIVCIATSRDGRQMAVKKMDLRKQQRRELLFNEVVVMRDYHHPN 261
Query: 326 LVQLYA--VVSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIER 383
+V++Y +V++E +++V E+M G+L D + + +++ + + +A++
Sbjct: 262 IVEMYNSYLVNDE-LWVVMEFMEGGALTDIVTNNRMDEVQIATVCRACLK---ALAFLHA 429
Query: 384 MNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRF 443
IHRD++S +IL+ + K+ DFG + + + P W APE +
Sbjct: 430 NGVIHRDIKSDSILLSHDGKVKLXDFGFCAQVTQDLQKRKSLVGTPY-WMAPEVISRLPY 606
Query: 444 TIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQ 489
+ D+WS GI++ E++ P N L+ + R MP P+
Sbjct: 607 GPEVDIWSLGIMVMEMIDAE----PPFFNEPPLQAMRRIRDMPPPK 732
>18921
Length = 697
Score = 72.4 bits (176), Expect = 4e-13, Method: Compositional matrix adjust.
Identities = 51/201 (25%), Positives = 89/201 (44%), Gaps = 1/201 (0%)
Frame = +2
Query: 267 PRESLQLIKRLGNGQFGEVWMGTWNGNTKVAIKTLKPGTMSPESFLEEAQIMKKLKHDKL 326
P + ++ +LG G +G V+ +V P + ++E IM++ +
Sbjct: 23 PEDVFDILGKLGEGSYGSVFKSLHKETGQVLAIKQVPVDTDLQEIIKEISIMQQCDSKYI 202
Query: 327 VQLY-AVVSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMN 385
V+ Y + ++IV EY GS+ D ++ + L + + G+ Y+
Sbjct: 203 VKYYGSYFKNTDLWIVMEYCGAGSVSDIMRL-RNKTLVEREIATILYYTLKGLXYLHSRR 379
Query: 386 YIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTI 445
IHRD+++ NIL+ N K+ADFG+A + D P W APE +
Sbjct: 380 KIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTPY-WMAPEVIQEIGYDC 556
Query: 446 KSDVWSFGILLTELVTKGRVP 466
+D+WS GI E+ +G+ P
Sbjct: 557 VADIWSLGITALEM-AEGKPP 616
>01707
Length = 757
Score = 70.5 bits (171), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 63/222 (28%), Positives = 113/222 (50%), Gaps = 9/222 (4%)
Frame = +1
Query: 269 ESLQLIKRLGNGQFGEVWMGTWNGNTK-VAIKTLKPGTMSP---ESFLEEAQIMKKLKHD 324
E + I ++G G +G V+ ++ VAIK P + + E +++K+LKH
Sbjct: 64 EKYEKIGKIGEGSYGVVFKCRNKETSQLVAIKKFVESEDDPLIKKIAMREIRMLKQLKHP 243
Query: 325 KLVQLYAVVSEEP-IYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIER 383
LV+L V + +++V +Y++ +LL+ L D R L P + + Q + + +
Sbjct: 244 NLVRLIEVFRRKKRLHLVFDYVDH-TLLNEL-DRYPRGLPEPMVKRIIYQTLLAVNFCHQ 417
Query: 384 MNYIHRDLRSANILVGNGLICKIADFGLARLIE--DNEYTARQGAKFPIKWTAPEAALYG 441
N IHRD++ NIL+ K+ DFG AR++ +EYT ++ + APE L G
Sbjct: 418 YNTIHRDVKPENILITRQGQVKLCDFGFARILTGPGDEYTDYVATRW---YRAPE-LLVG 585
Query: 442 --RFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVER 481
++ DVW+ G + EL+T G+ +PG ++ + L + +
Sbjct: 586 DTQYGPPVDVWAIGCVFAELLT-GQALWPGRSDVDQLHLIRK 708
>17253
Length = 483
Score = 69.7 bits (169), Expect = 3e-12, Method: Composition-based stats.
Identities = 45/153 (29%), Positives = 69/153 (45%), Gaps = 16/153 (10%)
Frame = -1
Query: 296 VAIKTLKPGTMSPE--SFLEEAQIMKKL-KHDKLVQLYAVVS-EEPIYIVTEYMNKGSLL 351
VA+KT E FL E IM+KL +H +V + +P I+ E+ G LL
Sbjct: 459 VAVKTHNEAATDAEKSEFLRELSIMRKLPRHPNVVSFMGCCTMSDPALILMEFCCHGDLL 280
Query: 352 DFLKD----------GEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNG 401
FL+ L + A VA GMA++ +HRD+ + N+L+
Sbjct: 279 SFLRKRRPDRTVFLTSTANDLTARDFFSFALHVARGMAHVANNKIVHRDVAARNVLISER 100
Query: 402 LICKIADFGLARLIEDNE--YTARQGAKFPIKW 432
+CK++DFGL+R + D Y P++W
Sbjct: 99 NVCKVSDFGLSRRVGDQNDVYEIVSRRPLPLRW 1
>01060
Length = 1800
Score = 69.3 bits (168), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 61/253 (24%), Positives = 116/253 (45%), Gaps = 11/253 (4%)
Frame = +1
Query: 264 WEIPRESLQLIKRLGNGQFGEVWMGTWNGN-TKVAIKTLK---PGTMSPESFLEEAQIMK 319
+E L +++G G +G V+ K+A+K ++ P S + E +++
Sbjct: 58 FETALSDLTDFQKIGEGTYGVVYKCRHRATGRKLAMKKIRLRGSEDGVPSSAIREIAMLR 237
Query: 320 KLKHDKLVQLYAVVSE-EPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGM 378
+L+H +V L V+ E E +++V E+++ + K EG L + Q+ G+
Sbjct: 238 ELRHTNIVCLEDVIMEDERLFLVFEFLSMDLKMYIDKFPEGVVLDRRLVKSYVFQIVTGI 417
Query: 379 AYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAA 438
+ + +HRDL+ N+L+ + KIADFG+AR A + + APE
Sbjct: 418 XFCHQRRIVHRDLKPQNLLINHTGAIKIADFGMARTFA-LPVRAYTHEVVTLWYRAPEIL 594
Query: 439 L-YGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPISLHE 497
+ +++ DVWS G + +++ + + + G + + L ++ R P Q P H+
Sbjct: 595 MGASKYSTPVDVWSIGTIFADMLIRTPI-FKGDSEIDQLFKIFRIIGTPTEQTWP-EFHK 768
Query: 498 L-----MIHCWKK 505
L M WK+
Sbjct: 769 LPAFNGMFPLWKE 807
>00300
Length = 2318
Score = 67.8 bits (164), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 62/266 (23%), Positives = 124/266 (46%), Gaps = 16/266 (6%)
Frame = -1
Query: 276 RLGNGQFGEVWMGT-WNGNTKVAIKTLK--PGTMSP-ESFLEEAQIMKKLKHDKLVQLYA 331
++G GQFG+V+ + +A+K +K P + +E +I + ++H+ LV+ Y
Sbjct: 1637 KIGEGQFGKVYTAVNMSTGELMALKEMKFQPNDLQQLREMCDEIKIFEGIQHENLVKYYG 1458
Query: 332 V-VSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLV--DMAAQVAAGMAYIERMNYIH 388
V V ++ + + EY + G++ + K G LP + ++ + ++ + +H
Sbjct: 1457 VEVHKDEMLMFMEYCDTGTIEEAAKMG------LPEYLIRRYTREIVLAVNHLHENSIVH 1296
Query: 389 RDLRSANILVGNGLICKIADFGLARLIEDN-----EYTARQGAK---FPIKWTAPEAALY 440
RD++ ANI + + K+ DFG + ++ + E+ G P +T + Y
Sbjct: 1295 RDIKGANIFLTSNGHVKLGDFGCSVKLKSHTTMPGEFHNLVGTTAYMAPEVFTQNDQGGY 1116
Query: 441 GRFTIKSDVWSFGILLTELVTKGRVPYPGM-NNREVLEQVERGYRMPCPQDCPISLHELM 499
GR +D+WS G ++ E+ T G+ P+ + NN +++ +V G++ P + +
Sbjct: 1115 GR---AADIWSLGCVVIEMAT-GKRPWHDLDNNYQIMYKVGIGHKPAVPDSLSVEGKHFL 948
Query: 500 IHCWKKDPEERPTFEYLQSFLEDYFT 525
DP +R L L+ FT
Sbjct: 947 DLIMCHDPAQRALASQL---LDHTFT 879
>14126
Length = 1265
Score = 66.2 bits (160), Expect = 3e-11, Method: Compositional matrix adjust.
Identities = 59/236 (25%), Positives = 108/236 (45%), Gaps = 16/236 (6%)
Frame = +3
Query: 277 LGNGQFGEVWMG--TWNGNTKVAIKTLKPGTMS---PESFLEEAQIMKKLK---HDKLVQ 328
+GNG +G V+ N VA+K ++ P + E ++K+L+ H +V+
Sbjct: 213 IGNGAYGTVYKARDLRNQGEFVAMKRIRLNNTEEGMPMMAIREISMLKQLEQYEHPNVVR 392
Query: 329 LYAVV------SEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIE 382
L V E + +V EY+ + L +L L + D+ Q+ G+ ++
Sbjct: 393 LLDVSHNTITDREIRLNLVFEYI-EHDLATYLAKCPSPGLGPDRIKDLMLQLLNGVDFLH 569
Query: 383 RMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGR 442
+HRDL+ N+L+ K+ADFGLAR+ + + A + + +PE +
Sbjct: 570 SNRIVHRDLKPQNLLISKDGRLKLADFGLARIY--SFHMALTTVVVTLWYRSPEVLMQAE 743
Query: 443 FTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCP--ISLH 496
+ D+WS G + EL T+ R + G + + L+++ +P D P +S+H
Sbjct: 744 YGTSVDIWSCGCIFAELFTR-RALFKGSSEFDQLKKIFEVIGLPPAGDWPEGVSVH 908
>29581
Length = 1278
Score = 66.2 bits (160), Expect = 3e-11, Method: Compositional matrix adjust.
Identities = 59/191 (30%), Positives = 91/191 (47%), Gaps = 11/191 (5%)
Frame = -2
Query: 301 LKPGTMSPESFLEEAQIMKKLKHDKLVQLYAVV---SEEPIYIVTEYMNK--GSLLDFLK 355
L+ +SP + + L+H +VQL VV S + +++V EY + SLLD +
Sbjct: 1244 LERDMVSPSVVCVRSTFLLNLRHQNIVQLQEVVVGKSLDSLFLVMEYCEQDLASLLDNMP 1065
Query: 356 DGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLI 415
+ + + Q+ G+ Y+ IHRDL+ +N+L+ + KIADFGLAR
Sbjct: 1064 APFSES----QVKCIVLQLLKGLRYLHEAFIIHRDLKVSNLLMTDKGCVKIADFGLAR-- 903
Query: 416 EDNEYTARQGAKFP----IKWTAPEAALYGRFTIKS--DVWSFGILLTELVTKGRVPYPG 469
Y Q P + + APE L+G T + D+WS G +L EL+ P
Sbjct: 902 ---NYGKPQKPMTPKVVTLWYRAPE-LLFGSKTHSTAIDMWSAGCILGELLGHK----PL 747
Query: 470 MNNREVLEQVE 480
M R L+Q+E
Sbjct: 746 MPGRSDLQQIE 714
>18484
Length = 635
Score = 63.2 bits (152), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 37/122 (30%), Positives = 65/122 (53%)
Frame = +1
Query: 358 EGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIED 417
EG+ K P AA++A G+ ++ I+RDL+ N+++ + KIADFG+ +
Sbjct: 25 EGK-FKEPVAAFYAAEIAVGLFFLHDQGIIYRDLKLDNVMLDSEGHIKIADFGMCKEGMT 201
Query: 418 NEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLE 477
+ T R P + APE LY ++ D W++G+LL E++ G+ P+ G + E+
Sbjct: 202 GDATTRTFCGTP-DYIAPEIVLYQPYSKSVDWWAYGVLLFEMLA-GQPPFDGEDEDELFS 375
Query: 478 QV 479
+
Sbjct: 376 SI 381
>25550
Length = 941
Score = 63.2 bits (152), Expect = 3e-10, Method: Compositional matrix adjust.
Identities = 29/63 (46%), Positives = 41/63 (65%)
Frame = +3
Query: 465 VPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKKDPEERPTFEYLQSFLEDYF 524
V YPG++ EV +ERGYRM PQ P ++ LM+ CW+ DP+ERPTF+ + LE+ F
Sbjct: 36 VXYPGVDLTEVYHLLERGYRMERPQGTPADVYILMLKCWQWDPKERPTFKEIHYLLENMF 215
Query: 525 TAT 527
+
Sbjct: 216 EKS 224
>14420
Length = 528
Score = 61.6 bits (148), Expect = 7e-10, Method: Compositional matrix adjust.
Identities = 40/166 (24%), Positives = 80/166 (48%), Gaps = 3/166 (1%)
Frame = +2
Query: 309 ESFLEEAQIMKKLKHDKLVQ-LYAVVSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNL 367
E + E +M++ ++ +V L + + E +++V E++ GSL D + + + +
Sbjct: 35 ELIINEILVMRENQNPNIVNYLDSYLVGEELWVVMEFLAGGSLTDVVTE---TCMDEGQI 205
Query: 368 VDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLI--EDNEYTARQG 425
+ + + ++ IHRD++S NIL+G K+ DFG + E ++ + G
Sbjct: 206 AAVCRECLQALEFLHENQVIHRDIKSDNILLGMDGSVKLTDFGFCAQLSPEQSKRSTMVG 385
Query: 426 AKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMN 471
+ W APE ++ D+WS G++ E++ +G PY N
Sbjct: 386 TPY---WMAPEVVTRKQYGPTVDIWSLGVMCIEMI-EGEPPYLNEN 511
>27546
Length = 426
Score = 61.2 bits (147), Expect = 1e-09, Method: Composition-based stats.
Identities = 36/114 (31%), Positives = 56/114 (49%), Gaps = 7/114 (6%)
Frame = -1
Query: 311 FLEEAQIMKKLKHDKLVQLYAVVSEEP-IYIVTEYMNKGSLLDFLKDGEGRALKLPNLVD 369
F E +I+ +L H ++Q+++++ P I+I Y KG +L +K +D
Sbjct: 339 FPRELEILTRLDHPNIIQIHSILQRGPKIFIFMRYAEKGDMLSHIKK--------TGPID 184
Query: 370 MAA------QVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIED 417
A Q+A + Y+ + HRDL+ NIL+ L KIADFG AR D
Sbjct: 183 EAQTKVWFFQMAKALQYLHSHDIAHRDLKCENILLSKRLNVKIADFGFARYCRD 22
>04591
Length = 1117
Score = 60.8 bits (146), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 44/169 (26%), Positives = 83/169 (49%), Gaps = 14/169 (8%)
Frame = -2
Query: 308 PESFLEEAQIMKKLKHDKLVQLYAVVSEEP---------IYIVTEYMN--KGSLLDFLKD 356
P + L E +I+++L+H+ +VQL + + Y++ EY + LL+ L+
Sbjct: 1089 PITALREIKILQQLEHENVVQLQEICHTQAGPYNRYKSTFYLIFEYCDYDLAGLLNNLR- 913
Query: 357 GEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLAR-LI 415
L + ++ +Q+ G+ YI +HRD+++ANIL+ + K+ADFGL+R +
Sbjct: 912 ---VKFSLADKKNLMSQLLNGLFYIHTKQILHRDIKAANILLTRDGVLKLADFGLSRPWV 742
Query: 416 EDNEYTARQGAKFPIKWTAPEAALYG--RFTIKSDVWSFGILLTELVTK 462
+ T R W P L G + + D+W G ++ E+ ++
Sbjct: 741 KSKRLTNR----VVTLWYRPPELLLGEREYGPEIDMWGVGCIMAEMWSR 607
>00392
Length = 668
Score = 58.5 bits (140), Expect = 6e-09, Method: Compositional matrix adjust.
Identities = 53/174 (30%), Positives = 88/174 (50%), Gaps = 10/174 (5%)
Frame = +3
Query: 309 ESFLEEAQIMKKLKHDKLVQLYAVVSE------EPIYIVTEYMNKGSLLDFLKDGEGRAL 362
+ F EEA+++K+L+H +V+ + E + I +VTE M G+L +LK + +
Sbjct: 66 QRFKEEAEMLKELQHPNIVRFFDYWEEHNHRNRKVIILVTELMTSGTLKTYLKRFKKPNV 245
Query: 363 KLPNLVDMAAQVAAGMAYIERMN--YIHRDLRSANILV-GNGLICKIADFGLARLIEDNE 419
K+ L + QV G+ ++ IHRDL+ NI + G KI D GLA L N+
Sbjct: 246 KI--LKNWCRQVLKGLYFLHTRTPPVIHRDLKCDNIFITGPTGSVKIGDLGLATL--KNQ 413
Query: 420 YTARQGAKFPIKWTAPEAALY-GRFTIKSDVWSFGILLTELVTKGRVPYPGMNN 472
A+ P ++ APE +Y + DV++FG+ + E+ + PY +N
Sbjct: 414 SFAKSVIGTP-EFMAPE--MYEEHYDEAVDVYAFGMCMLEMAS-SEYPYSECSN 563
>11228
Length = 2155
Score = 58.2 bits (139), Expect = 8e-09, Method: Compositional matrix adjust.
Identities = 41/149 (27%), Positives = 75/149 (50%), Gaps = 5/149 (3%)
Frame = -2
Query: 88 VALYDYEARTE-DDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYVAPVDS--- 143
VA+ Y T+ D+LSF KG+ F + N E W T E+G +P+ +V +D
Sbjct: 1662 VAMLSYRKATDSDELSFCKGDVFVVQNEMEDGWLWVTCERTKESGLVPAPFVKDLDGDYE 1483
Query: 144 -IQAEEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDWDDMKGDHVKH 202
+++ ++ L +++A +L+ G G+FL+R+SE G YSL D V+
Sbjct: 1482 PVESLPYFHSCLSKEEAVEKLMLAGE--GSFLVRQSENYPGDYSLFFLCEKD-----VRR 1324
Query: 203 YKIRKLDNGGYYITTRAQFETLQQLVQHY 231
++I + G ++ F++L +++ Y
Sbjct: 1323 FRIER--RGNQFLVGGRLFDSLDGVIKRY 1243
Score = 37.0 bits (84), Expect = 0.018, Method: Compositional matrix adjust.
Identities = 22/57 (38%), Positives = 31/57 (54%)
Frame = -1
Query: 132 YIPSNYVAPVDSIQAEEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLS 188
+I S AP + WY G+LGR AE L G++L+RESE+ G++ LS
Sbjct: 2011 HINSALTAPDQKL----WYHGRLGRAGAEELLRD--QDAGSYLVRESESKLGSFVLS 1859
>01966
Length = 1735
Score = 58.2 bits (139), Expect = 8e-09, Method: Compositional matrix adjust.
Identities = 32/107 (29%), Positives = 58/107 (54%), Gaps = 1/107 (0%)
Frame = -1
Query: 308 PESFLEEAQIMKKLKHDKLVQLYAVVSE-EPIYIVTEYMNKGSLLDFLKDGEGRALKLPN 366
P S + E ++++L+H +V L V+ E E +++V E+++ + K EG L
Sbjct: 1582 PSSAIREIAMLRELRHTNIVCLEDVIMEDERLFLVFEFLSMDLKMYIDKFPEGVVLDRRL 1403
Query: 367 LVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLAR 413
+ Q+ G+ + + +HRDL+ N+L+ + KIADFG+AR
Sbjct: 1402 VKSYVFQIVTGINFCHQRRIVHRDLKPQNLLINHTGAIKIADFGMAR 1262
>09606
Length = 1300
Score = 57.8 bits (138), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 53/224 (23%), Positives = 95/224 (42%), Gaps = 23/224 (10%)
Frame = -3
Query: 269 ESLQLIKRLGNGQFGEVWMGTWNGNTK-VAIKTLKPGTMSPESFLEEAQIMKKLKHDKLV 327
E+ L + LG G+ ++ G G VAI ++ PE ++ + H +V
Sbjct: 1115 ENFVLYEELGKGEHSIIYKGRRKGTINFVAIHCIEK-CKRPE-VTNTVRMTHDISHPNVV 942
Query: 328 QLYA-VVSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNY 386
Q + + +++V E GSL D L + L ++ D + G+ YI +
Sbjct: 941 QFHEWYETSNHLWLVVELCTGGSLADIL--AQDHHLPETSIRDFGIHLVTGLHYIHSLGI 768
Query: 387 IHRDLRSANILVGNGLICKIADFGLARLIEDNEYT-----ARQGAKFPIK---------- 431
+ DLR + +L+ + K ADFGL+++ +N A G ++ I+
Sbjct: 767 LFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQWNIQSAEEMMKQVP 588
Query: 432 ------WTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPG 469
+ APE +I SD+W+ G + E+ + G P+ G
Sbjct: 587 TSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFS-GHPPFLG 459
>03240
Length = 1683
Score = 57.0 bits (136), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 47/162 (29%), Positives = 77/162 (47%), Gaps = 9/162 (5%)
Frame = -3
Query: 274 IKRLGNGQFGEVWMGTWNGNTKV-AIKTLKPGTMSPESFLE----EAQIMKKLKHDKLVQ 328
IK LG G FGEV + N + A+KTL+ + + + E I+ + ++ +V+
Sbjct: 1276 IKTLGVGAFGEVSLCRKNDTGMLYAMKTLRKSDVLKRNQVAHVKAERDILAEADNEWVVK 1097
Query: 329 LYAVVSEEP-IYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYI 387
LY + +Y V +Y+ G L+ L E L P A++ + + RM +I
Sbjct: 1096 LYYSFQDHNYLYFVMDYVPGGDLMGLLIRME--ILDEPLARFYVAELVQAIESVHRMGFI 923
Query: 388 HRDLRSANILVGNGLICKIADFGLA---RLIEDNEYTARQGA 426
HRD++ NIL+ K+ DFGL R +++Y R G
Sbjct: 922 HRDIKPDNILIDRNGHIKLTDFGLCTGFRWTHNSKYYQRDGT 797
>31885
Length = 529
Score = 57.0 bits (136), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 46/169 (27%), Positives = 78/169 (46%), Gaps = 6/169 (3%)
Frame = -2
Query: 315 AQIMKKLKHDKLVQL-YAVVSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQ 373
++ +L H LV L YA EE +++V + G L ++ + + + + Q
Sbjct: 519 VDMLTRLDHPFLVNLWYAFQDEEDLFMVVDLFLGGDLRYHMQ--QEVSFREDCVKFYLCQ 346
Query: 374 VAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWT 433
+A + Y+ +HRD++ NIL+ C + DF +A +ED+E P +
Sbjct: 345 LALVLDYLRSQKIVHRDIKPDNILLDEQGHCHVTDFNIATQLEDDELATSTSGTRP--YM 172
Query: 434 APE---AALYGR--FTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLE 477
APE A+ R + D WS G+ L EL+ K R P+ +N + E
Sbjct: 171 APEVYGVAINERRGYGFPVDWWSLGVSLFELLKKRR-PFSVHSNTSLHE 28
>07836
Length = 1478
Score = 56.6 bits (135), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 62/217 (28%), Positives = 100/217 (46%), Gaps = 42/217 (19%)
Frame = -1
Query: 338 IYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIE--------RMNYIHR 389
++++T+Y GSL D+L R L ++ +A G+A++ + HR
Sbjct: 1328 LFLITDYHENGSLHDYLL---SRVLDSSEMLALAHSAICGLAHLHIEIFGTRGKPAIAHR 1158
Query: 390 DLRSANILVGNGLICKIADFGLA-RLI-EDNEYTA----RQGAKFPIKWTAPEAALYGRF 443
D++S NILV C IAD GLA R I E NE RQG K ++ APE L
Sbjct: 1157 DIKSKNILVKKNGTCCIADLGLAVRYISESNEVDVAPNPRQGTK---RYMAPE-VLEMLL 990
Query: 444 TIK-------SDVWSFGILLTEL----VTKG-----RVPY-------PGMNNREVLEQVE 480
+K +D+++FG+++ E+ V G +VP+ P + ++ V+
Sbjct: 989 NVKNFDAFKQADMYAFGLVMWEIARCCVIGGVAEEYQVPFYNCLPHDPSFEDVRLVVSVD 810
Query: 481 RGYRMPCP---QDCPI--SLHELMIHCWKKDPEERPT 512
+ R P Q+ PI + ++M CW +P R T
Sbjct: 809 K-VRPDIPLRWQEDPIMKVMVKVMCECWSGNPAARLT 702
>13066
Length = 551
Score = 56.2 bits (134), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 47/181 (25%), Positives = 80/181 (44%), Gaps = 12/181 (6%)
Frame = +3
Query: 285 VWMGTWNG----NTKVAIKTL----KPGTMSPESFLEEAQIMKKLKHDKLVQLYAVVSEE 336
V GT+N N K+A K + P + F E ++ KL H ++Q+++++
Sbjct: 15 VVHGTFNDGYGRNIKLACKIIDKEKAPVDFVEKFFPRELDLLTKLDHPYIIQIHSILQRX 194
Query: 337 PI-YIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSAN 395
P +I + +G LL +++ E +K Q+ + Y+ + HRDL+ N
Sbjct: 195 PKNFIFMRFAERGDLLTYIQ--EVGFVKEKQAKIWFYQMTTALNYLHSYDVAHRDLKCEN 368
Query: 396 ILVGNGLICKIADFGL--ARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIK-SDVWSF 452
IL+ + K+ADFG A + E E + + APE + K +D WS
Sbjct: 369 ILLSSHFNVKLADFGFACACITESGEKYMSRTYCGSAAYAAPEIVYGAPYAPKVADAWSL 548
Query: 453 G 453
G
Sbjct: 549 G 551
>12672
Length = 773
Score = 53.9 bits (128), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 40/164 (24%), Positives = 74/164 (45%), Gaps = 16/164 (9%)
Frame = +3
Query: 375 AAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPI---K 431
A+G+ Y+ ++HRD+++ANIL+ + K+ DF E Q A I
Sbjct: 21 ASGIQYLNDNGHVHRDIKTANILLDSEYTAKVGDFATVVSAPSGEGKTVQNASVVIGTAA 200
Query: 432 WTAPEAALYGRFTIKSDVWSFGILLTELVT----------KGRVPYPGMNNREVLEQVER 481
+ APE A++ + K D +SFG++L E++T + + M N E E++
Sbjct: 201 YLAPE-AIHFDVSTKLDSYSFGVVLLEVITGLVAQDYSREERTLSSHIMENVEEPEEIHD 377
Query: 482 GYRMPC---PQDCPISLHELMIHCWKKDPEERPTFEYLQSFLED 522
P L+++ + C ++RP + ++ LE+
Sbjct: 378 FVDQSAGTWPDGAVDKLYDISMRCLNLSKKQRPNVKDIRPELEE 509
>13212
Length = 1067
Score = 52.8 bits (125), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 45/167 (26%), Positives = 76/167 (45%), Gaps = 11/167 (6%)
Frame = -1
Query: 373 QVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKF---P 429
++ + ++ R + IHRD+++ N+L+ K+ADFG++ N T ++ F P
Sbjct: 956 EMCMALDFLHRHHVIHRDIKAGNVLLTIDGEVKLADFGVSA---KNTQTQQKRDTFIGTP 786
Query: 430 IKWTAPEAALY-----GRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERG-- 482
W APE L + K+D+WS G+ L E + P M+ VL ++ +
Sbjct: 785 Y-WMAPEVVLCETLKDTPYDFKADIWSLGVTLIEFA-QIEPPNKEMHPMRVLIKIHKSDP 612
Query: 483 YRMPCPQDCPISLHELMIHCWKKDPEERPT-FEYLQSFLEDYFTATE 528
+ P+ + + C KDP RPT E L+ TAT+
Sbjct: 611 PTLEKPKKWTKLFKDFIAKCLVKDPNLRPTAAELLEHPFMKRATATD 471
>04138
Length = 800
Score = 52.4 bits (124), Expect = 5e-07, Method: Compositional matrix adjust.
Identities = 32/95 (33%), Positives = 48/95 (50%), Gaps = 7/95 (7%)
Frame = +1
Query: 378 MAYIERMNYIHRDLRSANILVGNGLICKIADFGLAR-----LIEDNEYTARQGAKFPIKW 432
+ YI R +HRD+++ANIL+ + K+ADFGLAR L + N YT R W
Sbjct: 52 LYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNR----VVTLW 219
Query: 433 TAPEAALYG--RFTIKSDVWSFGILLTELVTKGRV 465
P L G ++ D W G ++ E+ T+ +
Sbjct: 220 YRPPELLLGDRNYSTAIDQWGAGCIMAEMWTRNPI 324
>21079
Length = 878
Score = 51.6 bits (122), Expect = 8e-07, Method: Compositional matrix adjust.
Identities = 39/143 (27%), Positives = 69/143 (48%), Gaps = 4/143 (2%)
Frame = +1
Query: 323 HDKLVQLY-AVVSEEPIYIVTEYMNKGSLLD-FLKDGEGRALKLPNLVDMAAQVAAGMAY 380
H KL+ L+ A + + +V E++ G L + ++D L + V Q+ +G+ Y
Sbjct: 1 HPKLLMLWDAFEAPRTMVLVMEFVGAGELFERVIRDD--FVLTERDCVHFVRQICSGVGY 174
Query: 381 IERMNYIHRDLRSANILV--GNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAA 438
+ + +H DL+ N+L N KI DFGLAR + + + Q ++ APE
Sbjct: 175 MHTQSILHLDLKPENVLCVSDNSNQIKIIDFGLARFYKPGD--SLQVLFGTPEFIAPEVV 348
Query: 439 LYGRFTIKSDVWSFGILLTELVT 461
Y +D+WS G++ L++
Sbjct: 349 NYDEINFTTDMWSIGVICYILLS 417
>29243
Length = 1147
Score = 51.2 bits (121), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 32/98 (32%), Positives = 51/98 (52%), Gaps = 2/98 (2%)
Frame = +2
Query: 136 NYVAPVDSIQAEEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETT--KGAYSLSIRDWD 193
+YV S+++ WY G + R A++ L + P GTFLIR + +G SLSI+
Sbjct: 269 DYVNEPCSLESYNWYVGIMERPVAQKXLDTC--PDGTFLIRVTNNPLRRGELSLSIK--- 433
Query: 194 DMKGDHVKHYKIRKLDNGGYYITTRAQFETLQQLVQHY 231
+ V+H K+ + G +Y+ F+ +Q LV HY
Sbjct: 434 --YANAVRHIKVNRNPQGRFYLADGRYFDNIQSLVDHY 541
Score = 40.4 bits (93), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 21/58 (36%), Positives = 30/58 (51%), Gaps = 2/58 (3%)
Frame = +2
Query: 88 VALYDYEARTEDDLSFHKGEKFQIL--NSSEGDWWEARSLTTGETGYIPSNYVAPVDS 143
VA+YDY A + LS ++ IL N + WW+ +L T + GY P YV D+
Sbjct: 641 VAVYDYAATSTSQLSMKLNDRIAILSKNGQDKGWWKGENLRTQKIGYFPLAYVDEEDA 814
>12324
Length = 946
Score = 48.9 bits (115), Expect = 5e-06, Method: Compositional matrix adjust.
Identities = 22/53 (41%), Positives = 32/53 (60%)
Frame = +3
Query: 88 VALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYVAP 140
VA+YDYEA +D+L+F + ++ ++ WWE + G TG PSNYV P
Sbjct: 699 VAIYDYEAEKDDELTFSENSVIYVIRKNDDGWWEG--VMDGVTGLFPSNYVEP 851
>19094
Length = 898
Score = 48.5 bits (114), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 28/83 (33%), Positives = 41/83 (49%)
Frame = +1
Query: 377 GMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPE 436
G+ Y+ IHRD+++ NIL+ N K+ADFG+A + D P W APE
Sbjct: 94 GL*YLHSRRKIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTP-YWMAPE 270
Query: 437 AALYGRFTIKSDVWSFGILLTEL 459
+ +D+WS GI E+
Sbjct: 271 VIQEIGYDCVADIWSLGITALEM 339
>30755
Length = 1137
Score = 47.8 bits (112), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 37/142 (26%), Positives = 66/142 (46%), Gaps = 2/142 (1%)
Frame = +2
Query: 371 AAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEY--TARQGAKF 428
A++ + + Y+ I+RDL+ N+L+ K+ADFGL + ED Y T +
Sbjct: 50 GAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCK--EDITYGRTTKTFCGT 223
Query: 429 PIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCP 488
P ++ APE + D W G+++ E++ GR+P+ + +VL + + P
Sbjct: 224 P-EYLAPEVLDDNDYGRAVDWWGTGVVMYEMIC-GRLPFYN-RDHDVLFTLILVEDVKFP 394
Query: 489 QDCPISLHELMIHCWKKDPEER 510
++ L+ KDP R
Sbjct: 395 RNITDEAKSLLSGLLAKDPRNR 460
>15910
Length = 1361
Score = 47.8 bits (112), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 34/114 (29%), Positives = 57/114 (50%), Gaps = 3/114 (2%)
Frame = +2
Query: 372 AQVAAGMAYIERMNYIHRDLRSANIL---VGNGLICKIADFGLARLIEDNEYTARQGAKF 428
+ + G+ YI +HRDL+ N+L + + K+ADFGL+R+IE E
Sbjct: 485 SDILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLADFGLSRIIEP-EVQMSTVCGT 661
Query: 429 PIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERG 482
P + APE ++T D+WS G++ L+ G P+ N E+ ++ +G
Sbjct: 662 P-GYCAPEVLKGDKYTPSVDMWSVGVIAYILLC-GYEPFFAENEFEMYRKIIKG 817
>26560
Length = 398
Score = 46.6 bits (109), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 32/103 (31%), Positives = 52/103 (50%), Gaps = 1/103 (0%)
Frame = -1
Query: 371 AAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPI 430
AA+V G+ ++ ++RDL+ ANIL+ +I+D GLA A G
Sbjct: 338 AAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGLACDFSKKRPHASVGTH--- 168
Query: 431 KWTAPEAALYGR-FTIKSDVWSFGILLTELVTKGRVPYPGMNN 472
+ APE + G+ + +D +SFG +L +L+ KG P+ N
Sbjct: 167 GYMAPEVLMKGQSYDSSADWFSFGCMLYKLL-KGHSPFRQHNQ 42
>21210
Length = 518
Score = 45.8 bits (107), Expect = 5e-05, Method: Compositional matrix adjust.
Identities = 34/86 (39%), Positives = 47/86 (54%), Gaps = 4/86 (4%)
Frame = +3
Query: 435 PEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPG-MNNREVLEQVERGYRMPC-PQDCP 492
P A+ +G + ++SDVWS GI L EL T GR PY ++ + L+QV RG PC P D
Sbjct: 42 PRASSHG-YDVRSDVWSLGITLMELAT-GRFPYRKWVSIFDQLQQVVRGV-APCLPHDGA 212
Query: 493 IS--LHELMIHCWKKDPEERPTFEYL 516
S + C KD ++RP + L
Sbjct: 213 FSHDFVNFVNKCLTKDEKQRPKYNKL 290
>14257
Length = 919
Score = 45.4 bits (106), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 33/105 (31%), Positives = 52/105 (49%), Gaps = 5/105 (4%)
Frame = -3
Query: 147 EEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDWDDMKGDHVKHYKIR 206
EEWY GK+GRK+AE+ L G FL+RE+ + + LS R + +V+H +
Sbjct: 896 EEWYHGKIGRKEAEKLL----ELDGDFLVREASNSAAQFVLSGR-----QNGNVRHLLL- 747
Query: 207 KLDNGGYYITTRAQFETLQQLVQHYSERA-----AGLCCRLVVPC 246
+D G T F+++ L+ ++ + A G RLV P
Sbjct: 746 -VDPDGIVRTKDFIFDSVSHLINYHRQNALPIITEGSELRLVRPI 615
>19761
Length = 473
Score = 45.1 bits (105), Expect = 7e-05, Method: Compositional matrix adjust.
Identities = 34/119 (28%), Positives = 54/119 (45%), Gaps = 3/119 (2%)
Frame = -3
Query: 373 QVAAGMAYIERMN--YIHRDLRSANILVGNGLICKIADFGLAR-LIEDNEYTARQGAKFP 429
Q A+ + Y+ +HRDL+ NI V ++ D GLAR L ++ Q
Sbjct: 399 QTASALNYMHTHTPVILHRDLKPQNIYVTEKGDVRLGDLGLARKLTGPADFATSQVGT-- 226
Query: 430 IKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCP 488
I + +PE + KSD+WS G + ++ G+ M +L QV G ++P P
Sbjct: 225 IMYLSPEILSQQPYNSKSDIWSLGCVFYDIT--GKKGSDEMGVMFLLVQVMGGRKLPLP 55
>29687
Length = 434
Score = 45.1 bits (105), Expect = 8e-05, Method: Compositional matrix adjust.
Identities = 22/55 (40%), Positives = 32/55 (58%)
Frame = -2
Query: 89 ALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYVAPVDS 143
AL+DY A+ ED+LSF KG ++ +G WW T + + PSNYV +D+
Sbjct: 286 ALHDYNAKREDELSFCKGAIITNVSRQDGGWWRG-DYGTKKQHWFPSNYVEEIDT 125
>11185
Length = 473
Score = 44.3 bits (103), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 35/142 (24%), Positives = 61/142 (42%), Gaps = 25/142 (17%)
Frame = +1
Query: 369 DMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYT-----AR 423
D + G+ YI + + DLR + +L+ + K ADFGL+++ +N A
Sbjct: 13 DFGIHLVTGLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAE 192
Query: 424 QGAKFPIK----------------WTAPEAALYGRFTIKSDVWSFGILLTELVTKGRV-- 465
G ++ I+ + APE +I SD+W+ G + E+ + R+
Sbjct: 193 AGDQWNIQSAEEMMKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSGSRLSA 372
Query: 466 -PYPG-MNNREVLEQVERGYRM 485
P P +N E L Q + R+
Sbjct: 373 KPSPEFLNLLESLLQKDSTRRL 438
>16708
Length = 1397
Score = 42.4 bits (98), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 36/155 (23%), Positives = 78/155 (50%), Gaps = 11/155 (7%)
Frame = -1
Query: 271 LQLIKRLGNGQFGEVWMG-TWNGNTKVAIKTLKPGTMSPESFLEEAQIMKKLKHD-KLVQ 328
+ +++ LG G FG+V+ + + K A+KT ++ L+E + + +++ L Q
Sbjct: 1397 VAILQVLGKGVFGKVYEARLLSTHEKAALKT----SILCHHSLDEVEALGRIEGGFYLAQ 1230
Query: 329 LY-AVVSEEP---IYIVTEYMNKGSLLDFLKDGEGRALKL----PNLVD-MAAQVAAGMA 379
++ A V+ P + I+ + G L + + + + + P +V +A Q +
Sbjct: 1229 MFGAWVTCLPFPKMNILLHFYEMGPLCNVYAHYKNKEMPIRWSNPAMVCCIAGQXVCALE 1050
Query: 380 YIERMNYIHRDLRSANILVGNGLICKIADFGLARL 414
+I + +H D+++ N+LV CK+ D+G+A+L
Sbjct: 1049 HIHELGVVHMDVKADNVLVDAHGNCKLTDYGIAQL 945
>28638
Length = 1458
Score = 42.0 bits (97), Expect = 6e-04, Method: Compositional matrix adjust.
Identities = 35/109 (32%), Positives = 53/109 (48%), Gaps = 5/109 (4%)
Frame = -1
Query: 358 EGRALKLPNLVDMAAQVAAGMAYIE--RMNYIHRDLRSANILVGN---GLICKIADFGLA 412
EG +L L A Q+ + ++ MN IH DL+ NIL+ N I KI DFG +
Sbjct: 852 EGVSLNLTR--KFAQQLCTALLFLATPEMNIIHCDLKPENILLCNPKRSAI-KIVDFGSS 682
Query: 413 RLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVT 461
+ Y Q ++F + +PE L + + D+WS G +L E+ T
Sbjct: 681 CQLGQRIYQYIQ-SRF---YRSPEVLLGVPYDLAIDMWSLGCILVEMHT 547
>28095
Length = 597
Score = 41.6 bits (96), Expect = 8e-04, Method: Compositional matrix adjust.
Identities = 19/50 (38%), Positives = 28/50 (56%)
Frame = +3
Query: 89 ALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYV 138
A+YDY+A D++SF+ G+ + W R TG+ G +PSNYV
Sbjct: 270 AMYDYQAADSDEVSFNDGDTIIECQPVDAGWMTGRVERTGQYGMLPSNYV 419
>26711
Length = 405
Score = 41.2 bits (95), Expect = 0.001, Method: Composition-based stats.
Identities = 31/111 (27%), Positives = 54/111 (48%), Gaps = 3/111 (2%)
Frame = -2
Query: 373 QVAAGMAYIERMNYIHRDLRSANILVGNGLI--CKIADFGLAR-LIEDNEYTARQGAKFP 429
QV + ++ +H DL+ +N+L+ + ++ DFGLAR L E G
Sbjct: 392 QVLDILQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARKLYPPQETFLNHGTP-- 219
Query: 430 IKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVE 480
+T+PEA + SDVW G+L L++ G+ P+ + E L++ +
Sbjct: 218 -GFTSPEALDVKPISTASDVWGVGVLAYILLS-GQSPFQADSATESLKKTQ 72
>12786
Length = 460
Score = 41.2 bits (95), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 27/107 (25%), Positives = 51/107 (47%), Gaps = 21/107 (19%)
Frame = -3
Query: 387 IHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPI-KWTAPEAALYG---- 441
IH DL+ AN ++ G + K+ DFG+A ++ ++ + + ++ + +PEA +
Sbjct: 344 IHSDLKPANFMLVAGNL-KLIDFGIANTLQQDKTSVLKDSRVGTPSYMSPEAIMAACDDS 168
Query: 442 ----------------RFTIKSDVWSFGILLTELVTKGRVPYPGMNN 472
+ ++SDVWS G +L +V GR P+ + N
Sbjct: 167 ADDSMEEDGHRTKPKYKVGVRSDVWSLGCILYNMVY-GRTPFQHIKN 30
>05206
Length = 1075
Score = 40.8 bits (94), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 19/50 (38%), Positives = 27/50 (54%)
Frame = +1
Query: 89 ALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYV 138
ALY +EA E + + E+ QIL +GD W G G++PS+YV
Sbjct: 103 ALYPFEAMNEGSVPMGENEEMQILEEDQGDGWTRVRKADGSEGFVPSSYV 252
>01494
Length = 2122
Score = 40.4 bits (93), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 30/107 (28%), Positives = 49/107 (45%), Gaps = 5/107 (4%)
Frame = +3
Query: 89 ALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYVAPVDS---IQ 145
AL+DY A +D+LSF KG ++ +G WW + + PSN+V +++ +
Sbjct: 318 ALHDYNANRDDELSFCKGAIITNVSRQDGGWWRG-DYGAKKQHWFPSNFVEEIETHSDVN 494
Query: 146 AEEWYFGKL--GRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIR 190
++ G L G D + L+ PRG K A+ +S R
Sbjct: 495 SDSMPLGSLQQGSFDIQGCLVEPLAPRG---------DKSAFRISTR 608
>37602
Length = 804
Score = 40.4 bits (93), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 23/77 (29%), Positives = 37/77 (48%)
Frame = -1
Query: 333 VSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLR 392
+ E ++I EY GS+ D L P + + + G+ Y+ R +HRD++
Sbjct: 309 LRREKLWIAMEYCGGGSMQDIYH--VTGPLTEPQIAFVCRETLKGLHYLHRRGKMHRDIK 136
Query: 393 SANILVGNGLICKIADF 409
ANIL+ K+ADF
Sbjct: 135 GANILLTEEGDVKLADF 85
>06462
Length = 1511
Score = 40.4 bits (93), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 32/119 (26%), Positives = 48/119 (40%)
Frame = +1
Query: 133 IPSNYVAPVDSIQAEEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDW 192
+PS+ D E WY GK+ R++AE+ L G FL+RES + LS +
Sbjct: 1048 MPSSETGVTDPPLHELWYHGKMSRREAEKLL----GKDGDFLVRESGHNXSQFVLSGK-- 1209
Query: 193 DDMKGDHVKHYKIRKLDNGGYYITTRAQFETLQQLVQHYSERAAGLCCRLVVPCHKGMP 251
H + + +D G T F+ + LV ++ CH GMP
Sbjct: 1210 -----HHGQFIHLLLVDPDGIVRTKDYIFDNISHLVSYH--------------CHHGMP 1329
>32000
Length = 644
Score = 39.7 bits (91), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 28/83 (33%), Positives = 43/83 (51%), Gaps = 1/83 (1%)
Frame = -1
Query: 405 KIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRF-TIKSDVWSFGILLTELVTKG 463
KIADFGLAR+ T + + APE L RF ++ D+WS G + E++T+
Sbjct: 569 KIADFGLARVFGLPVRTYTHEV-ITLWYRAPEILLGCRFYSVPVDIWSLGCIFVEMMTR- 396
Query: 464 RVPYPGMNNREVLEQVERGYRMP 486
R +PG + + L ++ R P
Sbjct: 395 RALFPGDSEIDQLYRIFRTLGTP 327
>18481
Length = 437
Score = 39.7 bits (91), Expect = 0.003, Method: Composition-based stats.
Identities = 21/65 (32%), Positives = 37/65 (56%), Gaps = 3/65 (4%)
Frame = -1
Query: 360 RALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICK---IADFGLARLIE 416
R L ++ ++ Q+ + + +I + +IHRDL+ N L+G G C I DFGL++ +
Sbjct: 212 RRFTLKTILMVSDQLLSRLEFIHQKCFIHRDLKPDNFLMGLGRHCHRLYIIDFGLSKRYK 33
Query: 417 DNEYT 421
D + T
Sbjct: 32 DTQGT 18
>32264
Length = 287
Score = 39.3 bits (90), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 18/44 (40%), Positives = 29/44 (65%)
Frame = +1
Query: 479 VERGYRMPCPQDCPISLHELMIHCWKKDPEERPTFEYLQSFLED 522
+E GYR+ P S+++LM+ CW+ PE+RP F+ L + L+D
Sbjct: 1 IEDGYRLQQNPQTPDSVYKLMLRCWEYVPEKRPHFKELYTSLKD 132
>35671
Length = 567
Score = 38.5 bits (88), Expect = 0.007, Method: Compositional matrix adjust.
Identities = 15/47 (31%), Positives = 28/47 (59%)
Frame = -3
Query: 480 ERGYRMPCPQDCPISLHELMIHCWKKDPEERPTFEYLQSFLEDYFTA 526
++G R+ P C +++M+ CW + EERPTF+ L +E+ + +
Sbjct: 565 QKGNRLAKPISCTDEAYKVMLQCWTESREERPTFKKLVPVMENLYRS 425
>16716
Length = 934
Score = 37.7 bits (86), Expect = 0.012, Method: Compositional matrix adjust.
Identities = 28/111 (25%), Positives = 44/111 (39%)
Frame = -1
Query: 28 YRYGTDPTPQHYPSFGVTSIPNYNNFHAAGGQGLTVFGGVNSSSHXXXXXXXXXXXXXXF 87
Y +P PQH P + + A Q GG +++
Sbjct: 577 YEVSEEPAPQHEPEESPYEMADEEPAAPAQSQP----GGGSTA----------------- 461
Query: 88 VALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYV 138
+ALYDY+A +D+L+F + + + WW R G+ G P+NYV
Sbjct: 460 IALYDYQAADDDELTFDPDDVITDIEMIDDGWW--RGSCHGKNGLFPANYV 314
>17286
Length = 489
Score = 37.4 bits (85), Expect = 0.014, Method: Compositional matrix adjust.
Identities = 17/56 (30%), Positives = 31/56 (55%)
Frame = +3
Query: 89 ALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYVAPVDSI 144
A+YD+ ++ +L F +G+ +++ + +W+E G+ GY P NYV V I
Sbjct: 36 AIYDFLPESDGELGFQEGDMITLISQVDENWFEGS--VHGKVGYFPINYVEVVVPI 197
>27405
Length = 532
Score = 37.4 bits (85), Expect = 0.014, Method: Compositional matrix adjust.
Identities = 32/121 (26%), Positives = 52/121 (42%)
Frame = -3
Query: 330 YAVVSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHR 389
YA + E + + + MN G L L + + AA+V G+ ++ ++R
Sbjct: 353 YAFQTPEKLCFILDLMNGGDLHYHLS--QHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYR 180
Query: 390 DLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDV 449
DL+ ANIL+ +I+D GLA + A G + APE + G+ S
Sbjct: 179 DLKPANILLDENGHVRISDLGLACDFSKKKPHASVGTH---GYMAPEVLMKGQAYDSSAD 9
Query: 450 W 450
W
Sbjct: 8 W 6
>30740
Length = 488
Score = 37.4 bits (85), Expect = 0.017, Method: Compositional matrix adjust.
Identities = 13/33 (39%), Positives = 21/33 (63%)
Frame = +2
Query: 91 YDYEARTEDDLSFHKGEKFQILNSSEGDWWEAR 123
YD+ R +DL F KG+ ++++ E +WW AR
Sbjct: 203 YDFSGRDPEDLPFSKGDILELISKDEEEWWTAR 301
>38046
Length = 446
Score = 36.6 bits (83), Expect = 0.023, Method: Composition-based stats.
Identities = 15/26 (57%), Positives = 20/26 (76%)
Frame = -1
Query: 374 VAAGMAYIERMNYIHRDLRSANILVG 399
+A MAY+E+ N+IHR+L NILVG
Sbjct: 98 IADAMAYMEKENFIHRNLGDRNILVG 21
>21433
Length = 590
Score = 35.8 bits (81), Expect = 0.044, Method: Compositional matrix adjust.
Identities = 25/89 (28%), Positives = 40/89 (44%)
Frame = +2
Query: 373 QVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKW 432
Q+++ + Y IHRD++ N+L+G KIADFG + + T G + +
Sbjct: 191 QLSSALEYCHYRKVIHRDIKPENLLLGLKGDLKIADFGWSVHAPSSRRTTMCGT---LDY 361
Query: 433 TAPEAALYGRFTIKSDVWSFGILLTELVT 461
PE D+WS G+L E +
Sbjct: 362 LPPEMVEGKTHDENVDLWSLGVLCYEFLV 448
>18881
Length = 762
Score = 35.4 bits (80), Expect = 0.060, Method: Compositional matrix adjust.
Identities = 22/67 (32%), Positives = 35/67 (52%), Gaps = 2/67 (2%)
Frame = -3
Query: 169 PRGTFLIRESETTKGAYSLSIRDWDDMK--GDHVKHYKIRKLDNGGYYITTRAQFETLQQ 226
P GTFLIR + T S R+ + V+H K+ + G +Y+ F+++QQ
Sbjct: 748 PDGTFLIRVTNT-------SARESCPQY*YANAVRHIKVNRNPQGRFYLADGHYFDSVQQ 590
Query: 227 LVQHYSE 233
LV+HY +
Sbjct: 589 LVEHYEK 569
Score = 28.5 bits (62), Expect = 6.3, Method: Compositional matrix adjust.
Identities = 14/45 (31%), Positives = 22/45 (48%), Gaps = 2/45 (4%)
Frame = -3
Query: 101 LSFHKGEKFQIL--NSSEGDWWEARSLTTGETGYIPSNYVAPVDS 143
++ ++ IL N + WW+ +L T + GY P YV DS
Sbjct: 436 VTLKLNDRISILSKNGQDKGWWKGENLRTKKVGYFPLAYVDEEDS 302
>01392
Length = 1806
Score = 35.4 bits (80), Expect = 0.061, Method: Compositional matrix adjust.
Identities = 32/109 (29%), Positives = 51/109 (46%), Gaps = 12/109 (11%)
Frame = -1
Query: 373 QVAAGMAYIERMNYIHRDLRSANIL---VGNGLICKIADFGLARLIE-DNEYTARQGAKF 428
+A + ++ HRDL+ NIL + + + KI DF LA I D + T
Sbjct: 1767 HIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGISCDGDGTKTPELLT 1588
Query: 429 PI---KWTAPEA--ALYG---RFTIKSDVWSFGILLTELVTKGRVPYPG 469
P+ ++ APE A G + + D+WS GI+L ++ G P+ G
Sbjct: 1587 PVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILYIMLC-GYPPFYG 1444
>00394
Length = 548
Score = 35.4 bits (80), Expect = 0.063, Method: Compositional matrix adjust.
Identities = 28/96 (29%), Positives = 47/96 (48%), Gaps = 11/96 (11%)
Frame = -2
Query: 271 LQLIKRLGNGQFGEVWMGTWNGNTKVAI-----KTLKPGTMSPESFLEEAQIMKKLKHDK 325
L+ K +G G F V+ G + VA+ + K + F EEA+++K+L+H
Sbjct: 292 LKFDKEIGRGSFKTVYKGL-DTELGVAVAWCELQDKKWNKAERQRFKEEAEMLKELQHPN 116
Query: 326 LVQLYAVVSE------EPIYIVTEYMNKGSLLDFLK 355
+V+ + E + I +VTE M G+L +LK
Sbjct: 115 IVRFFDYWEEHNHRNRKVIILVTELMTSGTLKTYLK 8
>07933
Length = 728
Score = 35.0 bits (79), Expect = 0.070, Method: Compositional matrix adjust.
Identities = 13/30 (43%), Positives = 18/30 (60%)
Frame = +3
Query: 488 PQDCPISLHELMIHCWKKDPEERPTFEYLQ 517
P CP L+ +M+ CW +P RPTF L+
Sbjct: 3 PNYCPNLLYNIMMQCWSAEPSARPTFHKLE 92
>13664
Length = 507
Score = 35.0 bits (79), Expect = 0.078, Method: Compositional matrix adjust.
Identities = 16/45 (35%), Positives = 25/45 (55%)
Frame = +2
Query: 88 VALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGY 132
VALYDY+A+ D+L+ G+ +L+ WW L G+ G+
Sbjct: 374 VALYDYKAQRSDELTILSGDVIMLLHKDSESWWMGE-LLDGQQGF 505
>36481
Length = 806
Score = 35.0 bits (79), Expect = 0.082, Method: Compositional matrix adjust.
Identities = 37/150 (24%), Positives = 64/150 (42%), Gaps = 13/150 (8%)
Frame = +2
Query: 261 KDVWEIPR-----ESLQLIKRLGNGQFGEVWM--GTWNGNTKVAIKTLKPGTMSPESFLE 313
KD+W R ++L G G FG+V G+ +A+K +K E+
Sbjct: 323 KDIWCTMRGTSSTNDMKLCPHWGEGTFGKVVQCKDLLKGD-DIALKIIKNVDKYREAAKL 499
Query: 314 EAQIMKKLK----HDK--LVQLYAVVSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNL 367
E +++KL+ H K VQ+ ++ +M S+ DFLKD A + +
Sbjct: 500 EINVLEKLREKDPHAKHMCVQMLDWFDYHGHVCISFHMLGLSVFDFLKDNSYGAYPIEQV 679
Query: 368 VDMAAQVAAGMAYIERMNYIHRDLRSANIL 397
++ Q+ + ++ H DL+ NIL
Sbjct: 680 RHISYQLCYAVNFLHENQLTHTDLKPENIL 769
>02638
Length = 1490
Score = 33.9 bits (76), Expect = 0.15, Method: Compositional matrix adjust.
Identities = 25/103 (24%), Positives = 49/103 (47%), Gaps = 7/103 (6%)
Frame = +1
Query: 430 IKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRM---- 485
I + APE + DVWS G ++ E+ T R P+ N+ ++ + +++
Sbjct: 28 IAFMAPEVLRGESYGRACDVWSVGCVMIEMCT-CRPPW---NSHDISNHLALIFKIASSV 195
Query: 486 ---PCPQDCPISLHELMIHCWKKDPEERPTFEYLQSFLEDYFT 525
P P++ + +LM+ C ++D + RP+ + L + FT
Sbjct: 196 DPPPIPENMSPPVRDLMLRCLEQDSDFRPSAKDL--LMHPLFT 318
>31789
Length = 676
Score = 33.9 bits (76), Expect = 0.17, Method: Compositional matrix adjust.
Identities = 30/113 (26%), Positives = 53/113 (46%), Gaps = 11/113 (9%)
Frame = +2
Query: 277 LGNGQFGEVWMGTWNGNTKVAI-----KTLKPGTMSPESFLEEAQIMKKLKHDKLVQLYA 331
+G G F V+ G + VA+ + K + F EEA+++K+L+H +V+ +
Sbjct: 344 IGRGSFKTVYKGL-DTELGVAVAWCELQDKKWNKTERQRFKEEAEMLKELQHPNIVRFFD 520
Query: 332 VVSE------EPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGM 378
E + I +VTE M G+L +LK + + L L + Q+ G+
Sbjct: 521 YWEEHNHRNRKVIILVTELMTSGTLKTYLK--RFKKINLKVLKNWCRQILKGL 673
>37260
Length = 401
Score = 33.9 bits (76), Expect = 0.17, Method: Composition-based stats.
Identities = 17/56 (30%), Positives = 30/56 (53%)
Frame = -1
Query: 149 WYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDWDDMKGDHVKHYK 204
WY+G L ++AE +L+ G+FL+R+S SLS + + ++H+K
Sbjct: 182 WYWGPLSYEEAESKLMD--KRDGSFLVRDSSNENYILSLSFKSMGHVHHTRIEHHK 21
>29360
Length = 363
Score = 33.9 bits (76), Expect = 0.19, Method: Composition-based stats.
Identities = 28/116 (24%), Positives = 50/116 (43%), Gaps = 7/116 (6%)
Frame = +3
Query: 290 WNGNTK--VAIKTLKPGTMSPESFLEEAQIMKKLKHD-----KLVQLYAVVSEEPIYIVT 342
W T VAIK LK E I+++L + V+ + + +
Sbjct: 12 WKKGTSEIVAIKILKNHPSYARQGQIEVSILQRLSQESADDYNFVRAFECFQHKNHTCLV 191
Query: 343 EYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILV 398
M + +L DFLK + + L L + + QV + ++++ IH DL+ NI++
Sbjct: 192 FEMLEQNLYDFLKQNKFQPLPLKYIRPITQQVLTALRKLKQLGLIHADLKPENIML 359
>32359
Length = 928
Score = 31.6 bits (70), Expect = 0.76, Method: Compositional matrix adjust.
Identities = 21/57 (36%), Positives = 32/57 (56%), Gaps = 2/57 (3%)
Frame = -1
Query: 275 KRLGNGQFGEVWMGTWNGNTK-VAIKTLKPGTMSPESFL-EEAQIMKKLKHDKLVQL 329
K +GNG FG V+ ++ VAIK + + + F E QIM+KL+H +V+L
Sbjct: 412 KVIGNGSFGVVYQAKLVDTSELVAIKKV----LQDKRFKNRELQIMRKLEHQNIVKL 254
>32357
Length = 625
Score = 31.6 bits (70), Expect = 0.86, Method: Compositional matrix adjust.
Identities = 14/43 (32%), Positives = 26/43 (60%), Gaps = 1/43 (2%)
Frame = -2
Query: 272 QLIKRLGNGQFGEVWMGTWN-GNTKVAIKTLKPGTMSPESFLE 313
+L+K++G+G FGE+++G N +VA+K P+ + E
Sbjct: 429 RLMKKIGSGSFGEIYLGVHNTSGEEVAVKLELKNAKHPQLYYE 301
>17516
Length = 453
Score = 31.6 bits (70), Expect = 0.90, Method: Compositional matrix adjust.
Identities = 28/101 (27%), Positives = 47/101 (46%), Gaps = 6/101 (5%)
Frame = -3
Query: 434 APEAALY-GRFTIKSDVWSFGILLTELVTKGRVPYPGMNNR---EVLEQVERGYRMPCPQ 489
APE L G++ +K+DV+S I+L EL G+ +++ + + V+ G R
Sbjct: 415 APEVLLQKGQYDMKADVYSLAIILWEL-WYGQDAADHISSHLFGRLEDAVQAGLRPSVTM 239
Query: 490 DC--PISLHELMIHCWKKDPEERPTFEYLQSFLEDYFTATE 528
C P +L+ W+ +RPT F ED+ T+
Sbjct: 238 TCKPPDDWLKLLQSGWEFHASKRPTSRDAAEFFEDFLERTK 116
>18401
Length = 463
Score = 31.2 bits (69), Expect = 1.2, Method: Compositional matrix adjust.
Identities = 18/50 (36%), Positives = 27/50 (54%)
Frame = -3
Query: 432 WTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVER 481
+ APE L ++ DVWS G ++ EL T G + +N+E L +ER
Sbjct: 434 YRAPEVILELGWSHPCDVWSVGCIMFELYT-GYTLFQTHDNKEHLAMMER 288
>13641
Length = 2081
Score = 30.8 bits (68), Expect = 1.3, Method: Compositional matrix adjust.
Identities = 15/58 (25%), Positives = 28/58 (48%), Gaps = 9/58 (15%)
Frame = +2
Query: 89 ALYDYEARTEDD-------LSFHKGEKFQILNSSEGDWWEA--RSLTTGETGYIPSNY 137
A++ + ++ +D+ LSF +G+ I+N + WW+A G IPS +
Sbjct: 164 AMFSFNSKLDDNIPCKEAGLSFQQGDILHIVNQEDAIWWQAYKHGDAKKRAGLIPSRH 337
>23319
Length = 2235
Score = 30.8 bits (68), Expect = 1.3, Method: Compositional matrix adjust.
Identities = 12/45 (26%), Positives = 24/45 (53%)
Frame = +3
Query: 435 PEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQV 479
P+ ++ D+WS G + EL GR +PG ++ + L+++
Sbjct: 3 PDVYXAKMYSTSIDMWSAGCIFAELANAGRPLFPGNDDDDQLKRI 137
>27287
Length = 514
Score = 30.8 bits (68), Expect = 1.5, Method: Compositional matrix adjust.
Identities = 11/30 (36%), Positives = 19/30 (63%)
Frame = -2
Query: 498 LMIHCWKKDPEERPTFEYLQSFLEDYFTAT 527
+M CW++DP +RP+F L L+ T++
Sbjct: 474 IMHSCWQEDPNDRPSFSRLVQELDKMLTSS 385
>29590
Length = 320
Score = 30.4 bits (67), Expect = 2.1, Method: Composition-based stats.
Identities = 13/43 (30%), Positives = 26/43 (60%)
Frame = +3
Query: 432 WTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNRE 474
+ APE Y +I++D+WS G+L ++T P+ G+ +++
Sbjct: 72 YVAPEVLDYEPLSIQTDMWSLGVLSYVMLTACS-PFVGITSKK 197
>27562
Length = 399
Score = 29.3 bits (64), Expect = 3.9, Method: Composition-based stats.
Identities = 18/54 (33%), Positives = 26/54 (48%), Gaps = 3/54 (5%)
Frame = -1
Query: 473 REVLEQVERGYRMPCPQDCPISLHELMIH-CWKKDPEERPT--FEYLQSFLEDY 523
R + Q+ R P+ C SL E++ WKKDP ER E L F++ +
Sbjct: 222 RVLWTQMRRRGTQIQPRPCSSSLFEIL*ETAWKKDPSERTENDIEILMDFMQHF 61
>18663
Length = 600
Score = 28.5 bits (62), Expect = 6.6, Method: Compositional matrix adjust.
Identities = 21/88 (23%), Positives = 36/88 (40%), Gaps = 8/88 (9%)
Frame = +2
Query: 431 KWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPY--------PGMNNREVLEQVERG 482
+ APE + D W+ G+LL E++ GR P+ P N + L QV
Sbjct: 23 NYIAPEILRGEDYGFSVDWWALGVLLYEMLA-GRSPFDIAGASENPDQNTEDYLFQVILE 199
Query: 483 YRMPCPQDCPISLHELMIHCWKKDPEER 510
+ P+ + ++ K+P +R
Sbjct: 200 KTIRIPRSLSVKAASVLKGFLNKNPADR 283
>15741
Length = 402
Score = 28.5 bits (62), Expect = 8.0, Method: Composition-based stats.
Identities = 11/32 (34%), Positives = 18/32 (56%)
Frame = -3
Query: 366 NLVDMAAQVAAGMAYIERMNYIHRDLRSANIL 397
+ A VA GMA++ +HRD+ + N+L
Sbjct: 97 DFFSFALHVARGMAHVANNKIVHRDVAARNVL 2
>32465
Length = 508
Score = 28.1 bits (61), Expect = 9.0, Method: Composition-based stats.
Identities = 18/71 (25%), Positives = 32/71 (45%), Gaps = 2/71 (2%)
Frame = +3
Query: 178 SETTKGAYSLSIRDWDDMKGDHVKHYKIRKLDNGGYYITTRAQFE--TLQQLVQHYSERA 235
SE + + S++ + + D V Y + Y T +++FE T Q V HY +
Sbjct: 207 SENER*SKKCSVQTTGNQQXDQVCFYLFCTITL*AYLSTEKSRFEXFTFSQTVHHYDIQL 386
Query: 236 AGLCCRLVVPC 246
+ LC + + C
Sbjct: 387 SKLCAKSKILC 419
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000357667 | hsapiens_gene_ensembl | Proto-oncogene
tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn) (Protooncogene
Syn) (SLK). [Source:Uniprot/SWISSPROT;Acc:P06241]
(537 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
21808 317 1e-87
06405 305 4e-83
11780 196 6e-70
09007 156 2e-38
04852 148 7e-36
17300 122 3e-33
14116 126 3e-29
20640 125 6e-29
07291 122 3e-28
07940 109 3e-24
08294 104 9e-23
18996 98 7e-21
22005 82 3e-20
01718 93 3e-19
17637 93 3e-19
13592 91 9e-19
14477 90 2e-18
19301 89 3e-18
13305 80 3e-15
01756 77 2e-14
00715 77 3e-14
12721 75 8e-14
18921 72 4e-13
01707 70 1e-12
17253 70 3e-12
01060 69 3e-12
00300 68 1e-11
14126 66 3e-11
29581 66 3e-11
18484 63 2e-10
25550 63 3e-10
14420 62 7e-10
27546 61 1e-09
04591 61 1e-09
00392 59 6e-09
11228 58 8e-09
01966 58 8e-09
09606 58 1e-08
03240 57 2e-08
31885 57 2e-08
07836 57 2e-08
13066 56 3e-08
12672 54 2e-07
13212 53 3e-07
04138 52 5e-07
21079 52 8e-07
29243 51 1e-06
12324 49 5e-06
19094 49 7e-06
30755 48 1e-05
15910 48 1e-05
26560 47 3e-05
21210 46 5e-05
14257 45 6e-05
19761 45 7e-05
29687 45 8e-05
11185 44 1e-04
16708 42 4e-04
28638 42 6e-04
28095 42 8e-04
26711 41 0.001
12786 41 0.001
05206 41 0.001
01494 40 0.002
37602 40 0.002
06462 40 0.002
32000 40 0.003
18481 40 0.003
32264 39 0.004
35671 39 0.007
16716 38 0.012
17286 37 0.014
27405 37 0.014
30740 37 0.017
38046 37 0.023
21433 36 0.044
18881 35 0.060
01392 35 0.061
00394 35 0.063
07933 35 0.070
13664 35 0.078
36481 35 0.082
02638 34 0.15
31789 34 0.17
37260 34 0.17
29360 34 0.19
32359 32 0.76
32357 32 0.86
17516 32 0.90
18401 31 1.2
13641 31 1.3
23319 31 1.3
27287 31 1.5
29590 30 2.1
27562 29 3.9
18663 28 6.6
15741 28 8.0
32465 28 9.0
>21808
Length = 1011
Score = 317 bits (813), Expect(2) = 1e-87, Method: Compositional matrix adjust.
Identities = 152/225 (67%), Positives = 180/225 (80%), Gaps = 1/225 (0%)
Frame = +1
Query: 288 GTWNGNTKVAIKTLKPGTMSPESFLEEAQIMKKLKHDKLVQLYAVVSEE-PIYIVTEYMN 346
G WN T VAIKTLK GTM P+ FL EAQIMKKL+H KL+QLYAV +++ PI+I+TE M
Sbjct: 4 GLWNNTTPVAIKTLKSGTMDPKDFLAEAQIMKKLRHPKLIQLYAVCTQDDPIFIITELMK 183
Query: 347 KGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKI 406
GSLL+FL+ G+GR LKLP L+D+ AQ+A GMAY+E NYIHRDL + NILV + KI
Sbjct: 184 NGSLLEFLQ-GKGRVLKLPALIDIGAQIACGMAYLESQNYIHRDLAARNILVSDNNTVKI 360
Query: 407 ADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVP 466
ADFGLAR+I+++EY AR GA+FPIKWTAPEAA Y RFTIKSDVWSFGILLTE VT GRVP
Sbjct: 361 ADFGLARVIKEDEYEARVGARFPIKWTAPEAANYNRFTIKSDVWSFGILLTETVTYGRVP 540
Query: 467 YPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKKDPEERP 511
YPGM N EVL QVE GYRMPCP CP L+++M+ CW+K+ ERP
Sbjct: 541 YPGMTNAEVLHQVEHGYRMPCPPGCPKPLYDIMLECWRKEEMERP 675
Score = 24.6 bits (52), Expect(2) = 1e-87, Method: Compositional matrix adjust.
Identities = 11/22 (50%), Positives = 14/22 (63%)
Frame = +2
Query: 511 PTFEYLQSFLEDYFTATEPQYQ 532
PTFE LQ LE++FT Y+
Sbjct: 674 PTFETLQWKLEEFFTMDSKDYR 739
>06405
Length = 1965
Score = 305 bits (780), Expect = 4e-83, Method: Compositional matrix adjust.
Identities = 164/351 (46%), Positives = 224/351 (63%), Gaps = 3/351 (0%)
Frame = +1
Query: 177 ESETTKGAYSLSIRDWDDMKGDHVKHYKIRKLDNGGYYITTRAQFETLQQLVQHYSERAA 236
ESE++ G S+S+R +G V HY+I + D+G ++T +F TL +LV H+S A
Sbjct: 1 ESESSPGQRSISVR----FEG-RVYHYRITE-DDGKVFVTQEHRFNTLAELVHHHSIHAD 162
Query: 237 GLCCRLVVPCHKGM-PRLTDLSVKTKDVWEIPRESLQLIKRLGNGQFGEVWMGTWNG-NT 294
GL L+ P K P + +S + D WEI R + + RLG GQ+G+V+ W N
Sbjct: 163 GLVTTLLYPAPKRQKPTVFGVSPEP-DRWEIERTEIAMKHRLGGGQYGDVYEAMWKRYNK 339
Query: 295 KVAIKTLKPGTMSPESFLEEAQIMKKLKHDKLVQLYAVVSEEP-IYIVTEYMNKGSLLDF 353
VA+KTLK TM+ FLEEA IMK++KH LVQL V + EP YIVTE+M G+LLD+
Sbjct: 340 IVAVKTLKEDTMALNDFLEEAAIMKEMKHPNLVQLLGVCTREPPFYIVTEFMPHGNLLDY 519
Query: 354 LKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLAR 413
L+ L+ MA Q+A+GMAY+E N+IHRDL + N LV + + K+ADFGLAR
Sbjct: 520 LRSSTREENGPTALMYMATQIASGMAYLETKNFIHRDLAARNCLVADSNMVKVADFGLAR 699
Query: 414 LIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNR 473
L++D+ YTA GAKFPIKWTAPE + RF+ +SD+W+FG+LL EL T G PYPG+
Sbjct: 700 LMKDDTYTAHIGAKFPIKWTAPEGLAFNRFSTRSDIWAFGVLLWELATYGMSPYPGVELT 879
Query: 474 EVLEQVERGYRMPCPQDCPISLHELMIHCWKKDPEERPTFEYLQSFLEDYF 524
EV +ERGYRM P P ++ LM+ CW+ DP++RPTF+ + LE+ F
Sbjct: 880 EVYHLLERGYRMERPPGTPADVYILMLKCWQWDPKDRPTFKEIHFLLENMF 1032
>11780
Length = 1713
Score = 196 bits (498), Expect(2) = 6e-70, Method: Compositional matrix adjust.
Identities = 123/341 (36%), Positives = 181/341 (53%), Gaps = 6/341 (1%)
Frame = +3
Query: 103 FHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYVAP--VDSIQAEEWYFGKLGRKDAE 160
F KG+ I ++ W + G G IP+NYV P V ++ A W+ GK+ R+ AE
Sbjct: 111 FQKGDLLVIRRATSDRMWYKACDSNGREGMIPANYVQPRKVVTLHAMPWFHGKITRQQAE 290
Query: 161 RQLLSFGNPR--GTFLIRESETTKGAYSLSIRDWDDMKGDHVKHYKIRKLDNGGYYITTR 218
L PR G FLIRES G Y+L + V+HY+I +N I
Sbjct: 291 ELL----KPREDGLFLIRESSNYPGDYTLCV-----CHLGKVEHYRILYRENQ-LTIDEE 440
Query: 219 AQFETLQQLVQHYSERAAGLCCRLVVPCHKGMPRLTDLSVK--TKDVWEIPRESLQLIKR 276
F L +LV+HY A GLC +L P K +S++ W I + L++ +
Sbjct: 441 GFFRNLDELVKHYLADADGLCTQLTRPVTKQGGNFGTVSLQEFKSGGWVIAXQDLEIGEA 620
Query: 277 LGNGQFGEVWMGTWNGNTKVAIKTLKPGTMSPESFLEEAQIMKKLKHDKLVQLYAVVSEE 336
+G G FG+V+ G + G VAIK LK +SFL+EA +M L+HD LV+L VV E
Sbjct: 621 IGKGDFGDVYKGMYRGQP-VAIKQLKDKDRGEQSFLQEASVMTSLRHDNLVRLIGVVLGE 797
Query: 337 PIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANI 396
I++VTE+M KG+L+++L+ + + ++ A A M Y+E +HRDL + N+
Sbjct: 798 TIFLVTEFMGKGNLVEYLRSRGRSVITKKDQINFATDTCAAMEYLESKRLVHRDLAARNV 977
Query: 397 LVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEA 437
LV + K++DFGLA+ + ++ + KFPIKWTAPEA
Sbjct: 978 LVHDDGKAKVSDFGLAKFGDFSQTS----VKFPIKWTAPEA 1088
Score = 86.7 bits (213), Expect(2) = 6e-70, Method: Compositional matrix adjust.
Identities = 41/86 (47%), Positives = 57/86 (66%)
Frame = +1
Query: 442 RFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIH 501
+FT KSD+WSFGILL E+ + GRVPYP + +V+ VERGYRM P+ CP ++ +M
Sbjct: 1102 KFTSKSDMWSFGILLWEIYSFGRVPYPRIPLTDVVMHVERGYRMEAPEGCPPEIYSIMKQ 1281
Query: 502 CWKKDPEERPTFEYLQSFLEDYFTAT 527
W+ DP ERPTF+ + + L + T
Sbjct: 1282 AWELDPNERPTFKSVLARLNNQRAVT 1359
>09007
Length = 1440
Score = 156 bits (394), Expect = 2e-38, Method: Compositional matrix adjust.
Identities = 98/283 (34%), Positives = 151/283 (53%), Gaps = 15/283 (5%)
Frame = -1
Query: 266 IPRESLQLIKRLGNGQFGEVWMGTWNGNT----KVAIKTLKPGTMSP--ESFLEEAQIMK 319
I ++ + L K LG G FG V W + +VA+K L + + FL+E IM+
Sbjct: 888 ISKDCVALSKSLGQGHFGTVRQAIWTAESGEKVQVAVKCLSKDKIHKDGQEFLKETAIMQ 709
Query: 320 KLKHDKLVQLYAVVSEE--PIYIVTEYMNKGSLLDFLKDGEGRA-LKLPNLVDMAAQVAA 376
L H+ +V++Y VV + I +VTE SLL+ +K+ R +P L D + QV
Sbjct: 708 MLDHENIVRVYGVVMDNGADIMLVTELAPMRSLLECVKEVSARVDFSVPRLCDFSQQVCD 529
Query: 377 GMAYIERMNYIHRDLRSANILVGNGLICKIADFGLA-RLIEDNEYTARQGA---KFPIKW 432
GM+Y+E +HRDL + NIL+ + KI+D G++ L EY Q + + W
Sbjct: 528 GMSYLESKRLVHRDLAARNILLFSKSKVKISDVGVSGALGAGKEYYQSQQTIHLQNAVAW 349
Query: 433 TAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVE--RGYRMPCPQD 490
APE+ F+ SDVW+FG+LL E T G P+ G+N ++++E V+ + R+ P
Sbjct: 348 CAPESFRNLCFSSASDVWAFGVLLWEFFTHGFQPWAGLNGQQIMEAVDAPQSQRLEQPDL 169
Query: 491 CPISLHELMIHCWKKDPEERPTFEYLQSFLEDYFTATEPQYQP 533
CP + +M+ CW+++P+ RPTF L FL T PQ +P
Sbjct: 168 CPKEYYAVMLKCWEQEPQRRPTFSQL--FL------TLPQIRP 64
>04852
Length = 1462
Score = 148 bits (373), Expect = 7e-36, Method: Compositional matrix adjust.
Identities = 87/259 (33%), Positives = 136/259 (52%), Gaps = 31/259 (11%)
Frame = +1
Query: 294 TKVAIKTLKPGTMSPE--SFLEEAQIMKKLK----HDKLVQLYAVVSEE-PIYIVTEYMN 346
+ VA+K L+ + E F++E Q+MK +K H +V ++ P++++ E+
Sbjct: 22 STVAVKMLRDIVTAVEEQDFVQELQVMKAVKKMGSHINIVNFLGCCTQGGPLWVIVEFAK 201
Query: 347 KGSLLDFL---KDG--------------------EGRALKLPNLVDMAAQVAAGMAYIER 383
G+L DFL +DG G ++ NL+ A Q+A GM ++
Sbjct: 202 NGNLRDFLESCRDGINGYGKFVSPQDPGWYTKTPGGHVIRRKNLLSYAFQIARGMEFLAS 381
Query: 384 MNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRF 443
IHRDL + N+LV + KIADFGL+R + Y R G + P+KW APEA R+
Sbjct: 382 RKCIHRDLAARNVLVTEEHVLKIADFGLSR--TGDYYKKRSGGRLPVKWMAPEALFDMRY 555
Query: 444 TIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQ-VERGYRMPCPQDCPISLHELMIHC 502
T KSDVWSFG++L E+ + G +PY + N E+ + ++ YRMP P+ +L+ +M C
Sbjct: 556 TTKSDVWSFGVVLWEIFSLGGMPYASIPNEELYSKLLDDAYRMPRPELASGNLYAIMERC 735
Query: 503 WKKDPEERPTFEYLQSFLE 521
W P +RP F L ++
Sbjct: 736 WLNRPSDRPEFSQLVGHID 792
>17300
Length = 480
Score = 122 bits (307), Expect(2) = 3e-33, Method: Compositional matrix adjust.
Identities = 56/117 (47%), Positives = 83/117 (70%), Gaps = 4/117 (3%)
Frame = +1
Query: 374 VAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDN----EYTARQGAKFP 429
+++GM + M Y+HRDL + NILV L+CK+ADFGL+R IE + YT + G K P
Sbjct: 1 ISSGMGXLADMGYVHRDLAARNILVNEILVCKVADFGLSREIESDTTEGAYTTK-GGKIP 177
Query: 430 IKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMP 486
++WTAPEA Y +FT SDVWSFG+++ E+++ G PY +N++V++ VE+GYR+P
Sbjct: 178 VRWTAPEAIAYRKFTSASDVWSFGVVMWEVMSYGERPYWNWSNQDVIKAVEKGYRLP 348
Score = 37.7 bits (86), Expect(2) = 3e-33, Method: Composition-based stats.
Identities = 16/43 (37%), Positives = 23/43 (53%), Gaps = 1/43 (2%)
Frame = +2
Query: 487 CPQ-DCPISLHELMIHCWKKDPEERPTFEYLQSFLEDYFTATE 528
CP DCP +LH+LM+ W+K+ RP + L+ A E
Sbjct: 344 CPSMDCPEALHQLMLDAWQKERSHRPKMSMVVKTLDKLIRAPE 472
>14116
Length = 1017
Score = 126 bits (316), Expect = 3e-29, Method: Compositional matrix adjust.
Identities = 75/216 (34%), Positives = 120/216 (55%), Gaps = 13/216 (6%)
Frame = -1
Query: 266 IPRESLQLIKRLGNGQFGEVWMGTWN-----GNTKVAIKTL---KPGTMSPESFLEEAQI 317
I RE L + + +G G FG V G G+ VA+KTL P + +SFL+EA I
Sbjct: 645 IDREFLTMGEEIGKGNFGCVKRGFLTLPEQKGDILVAVKTLHNNNPREIELQSFLQEALI 466
Query: 318 MKKLKHDKLVQLYAV---VSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQV 374
MK H ++ L + + + P+ +V +M G LL +++D + + + +L+ +
Sbjct: 465 MKDFHHSNVLTLIGICLNLDDMPL-VVLPFMKHGDLLTYIRDDQHQP-TIKDLIMYGVDI 292
Query: 375 AAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQG--AKFPIKW 432
A GM Y+ + ++HRDL + N ++ K+ADFGLAR I + EY + + AK P+KW
Sbjct: 291 ARGMDYLAGLKFVHRDLAARNCMLDEDFHVKVADFGLARDIYEKEYYSSENKKAKLPVKW 112
Query: 433 TAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYP 468
A E+ G + K+DVWS+G++L EL+T+G P
Sbjct: 111 MALESLEKGNYDSKTDVWSYGVVLWELLTRGSDALP 4
>20640
Length = 1492
Score = 125 bits (313), Expect = 6e-29, Method: Compositional matrix adjust.
Identities = 59/144 (40%), Positives = 86/144 (59%), Gaps = 1/144 (0%)
Frame = +1
Query: 386 YIHRDLRSANILVGNGLICKIADFGLARLIED-NEYTARQGAKFPIKWTAPEAALYGRFT 444
Y+HRDL + N LVG+ L+ KI+DFGLAR + + Y + PI+W EA LY +F+
Sbjct: 7 YVHRDLATRNCLVGHDLVVKISDFGLARSVHSVDYYRGSEHDAIPIRWMPLEAILYNKFS 186
Query: 445 IKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWK 504
+SDVWSFG++L E+ PY G+ + EV+ V+ G + CP+ P ++ELM CW
Sbjct: 187 TQSDVWSFGVVLWEIFAFALQPYYGLTHEEVVRFVKEGKVLACPERTPPPMYELMKQCWH 366
Query: 505 KDPEERPTFEYLQSFLEDYFTATE 528
+ P RP+F L LE+ + E
Sbjct: 367 RRPATRPSFHTLHKTLENMHSKYE 438
>07291
Length = 833
Score = 122 bits (306), Expect = 3e-28, Method: Compositional matrix adjust.
Identities = 60/167 (35%), Positives = 98/167 (58%), Gaps = 2/167 (1%)
Frame = +1
Query: 359 GRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLA-RLIED 417
+ L + L+D Q+A GMAY++ + +HR+L + N +V +++D+G+ L
Sbjct: 31 SKMLTVVQLLDFGRQIADGMAYLQEVKVVHRNLAARNCIVTEDGRLQLSDYGVTGSLFPQ 210
Query: 418 NEYTARQG-AKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVL 476
+ YTA A+ +KW APE F+ KSDVW+FG++L EL+T+G PYP + N +L
Sbjct: 211 SYYTADDSPARDLVKWMAPETIDNFHFSSKSDVWAFGVVLWELLTRGITPYPDVENSSLL 390
Query: 477 EQVERGYRMPCPQDCPISLHELMIHCWKKDPEERPTFEYLQSFLEDY 523
++ G+RM P+ P ++E+M CW + PE+RP F L L+ +
Sbjct: 391 PYLKEGHRMKKPKQSPEPVYEMMTACWNESPEQRPDFAELNDQLKTF 531
>07940
Length = 1336
Score = 109 bits (272), Expect = 3e-24, Method: Compositional matrix adjust.
Identities = 87/286 (30%), Positives = 125/286 (43%), Gaps = 70/286 (24%)
Frame = -3
Query: 255 DLSVKTKDVWEIPRESLQLIKRLGNGQFGEVW----MGTW--NGNTKVAIKTLKPGTMSP 308
DL + K WE PRE L L RLG G FG V MG + N + VA+K LK
Sbjct: 878 DLPLDAK--WEFPRERLVLGDRLGEGAFGLVMKGEAMGIFKDNNSVTVAVKMLKEDATDR 705
Query: 309 E--SFLEEAQIMKKL-KHDKLVQ----------LYAVVSEEPIYIVTEYMN--------- 346
E + E ++MK + KH ++ LY +V P + +++
Sbjct: 704 EMMDLIREMEMMKVIGKHKNIINLLGCCTQRGALYVIVEFAPHGNLRDFLKSHRPHGTSY 525
Query: 347 ----------------------------KGSLLDFL-------------KDGEGRALKLP 365
+G+ L F+ + + L
Sbjct: 524 SCIADYEQPVITSSSSSFSHPNSASSSAQGTSLGFIPGTSTVSFSTGSHRQDMLKMLTPK 345
Query: 366 NLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQ- 424
+L+ A QVA GM Y+ IHRDL + N+LV + KIADFGL R ++ +Y +
Sbjct: 344 DLISYAYQVARGMEYLASKQCIHRDLAARNVLVAEEYVLKIADFGLTRNLQQFDYYRKTT 165
Query: 425 GAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGM 470
+ P+KW APEA ++T KSDVWS+G+LL E+ T G PYP +
Sbjct: 164 DGRLPVKWMAPEALFDRKYTSKSDVWSYGVLLWEIFTLGGNPYPSV 27
>08294
Length = 1849
Score = 104 bits (260), Expect = 9e-23, Method: Compositional matrix adjust.
Identities = 64/207 (30%), Positives = 100/207 (48%), Gaps = 11/207 (5%)
Frame = +2
Query: 325 KLVQLYAVVSE-EPIYIVTEYMNKGSLLDFL-----KDGEGRALKLPNL-----VDMAAQ 373
+V V E EP +++TEY + G L FL +G GR ++P L + M Q
Sbjct: 890 NIVHFMGVCREAEPHFLITEYCDWGDLKQFLLATRNDNGRGRGTRVPALALSQKLGMGQQ 1069
Query: 374 VAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWT 433
VAAGM + +H DL + N+L+ + + K+A L+ + +EY P++W
Sbjct: 1070 VAAGMEALSNQGLVHGDLAARNVLLTSRMQLKVARPALSGDVYASEYYPLHQRLVPLRWL 1249
Query: 434 APEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPI 493
PE L T DVW+FG+ L E++ +PY M++ EVL ++ D P
Sbjct: 1250 PPEGVLEDSATTCGDVWAFGVFLWEVLQLADLPYRLMSDEEVLRSLQHSQAALDSPDAPP 1429
Query: 494 SLHELMIHCWKKDPEERPTFEYLQSFL 520
+L L+ C + P +RP F + S L
Sbjct: 1430 ALLSLLQRCTAQQPSQRPPFSEICSVL 1510
>18996
Length = 491
Score = 98.2 bits (243), Expect = 7e-21, Method: Compositional matrix adjust.
Identities = 55/136 (40%), Positives = 79/136 (58%), Gaps = 6/136 (4%)
Frame = +2
Query: 387 IHRDLRSANILVGNGLICKIADFGLARLIE-DNEYTARQGAKFPIKWTAPEAALYGRFTI 445
IHRDL + NILV + KI+DFGLA+ D Y PIKW +PEA +F+
Sbjct: 2 IHRDLAARNILVDRSCV-KISDFGLAQFANADGYYYGISQRDIPIKWYSPEAIETCKFSS 178
Query: 446 KSDVWSFGILLTELVTKGRVP--YPG--MNNREVLEQVERGYRMPCPQDCPISLH-ELMI 500
SDVWS+G+ L E+ ++G +P PG + E L ++ +G R+P P+ C ++ ELM
Sbjct: 179 YSDVWSYGVTLFEMFSRGEIPNLLPGHDLTQEEFLNRLRKGERLPKPELCSDFVYSELMR 358
Query: 501 HCWKKDPEERPTFEYL 516
CW + P+ RPTF +
Sbjct: 359 PCWHEMPKSRPTFHQI 406
>22005
Length = 873
Score = 82.4 bits (202), Expect(2) = 3e-20, Method: Compositional matrix adjust.
Identities = 58/194 (29%), Positives = 91/194 (46%), Gaps = 44/194 (22%)
Frame = +1
Query: 311 FLEEAQIMKKLKHDKLVQLYAVVS-EEPIYIVTEYMNKGSLLDFLKDGEGRALKLP---- 365
F EA +M H +V+L V + +P+ ++ E+M+KG L DFL+ LP
Sbjct: 151 FEREASLMADFDHPNIVKLLGVCAIGKPMCLLFEFMSKGDLNDFLRLCSPENYNLPVSRS 330
Query: 366 -NLVD-------------------------------------MAAQVAAGMAYIERMNYI 387
NLV ++ Q++AGMAY+ + +Y+
Sbjct: 331 QNLVVDLEDGLRVEVEAEECEKDTQSEDRDCSGMLXTKDQLYISQQISAGMAYLAQKDYV 510
Query: 388 HRDLRSANILVGNGLICKIADFGLARLIEDNEY-TARQGAKFPIKWTAPEAALYGRFTIK 446
HRDL + + I+DFGLAR + +Y + PI+W EA LY +F+ +
Sbjct: 511 HRDL-ATRTVXSRTT*S*ISDFGLARSVHSVDYYRGSEQDAIPIRWMPLEAILYSKFSTQ 687
Query: 447 SDVWSFGILLTELV 460
SDVWSFG++L E++
Sbjct: 688 SDVWSFGVVLWEIL 729
Score = 34.3 bits (77), Expect(2) = 3e-20, Method: Compositional matrix adjust.
Identities = 15/42 (35%), Positives = 24/42 (57%)
Frame = +3
Query: 466 PYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKKDP 507
PY G+ + EV+ V+ G + P P ++ELM CW++ P
Sbjct: 744 PYYGLTHEEVVNYVKAGKILEQPTKTPHQVYELMKQCWQRRP 869
>01718
Length = 959
Score = 92.8 bits (229), Expect = 3e-19, Method: Compositional matrix adjust.
Identities = 80/268 (29%), Positives = 130/268 (48%), Gaps = 16/268 (5%)
Frame = +3
Query: 273 LIKRLGNGQFGEVWMGTWNGNTKVAIKTLKPGTMSPESFLEEAQIMKKLKHDKLVQLYAV 332
+ +++G G F EV+ T +V + T + + L E Q++ +L+H +++ V
Sbjct: 159 ICEKIGAGFFSEVFKVTHRITGQVMALKMNTMTSNRHNMLREVQLLNRLQHANILRFMGV 338
Query: 333 -VSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLP--NLVDMAAQVAAGMAYIERMNYIHR 389
V E ++ +TEY+ G+L L E + +LP + + +A G+ Y+ +IHR
Sbjct: 339 CVHEGQLHALTEYIPSGNLEQLL---EKKDEELPWTQRIQLTLGLARGLDYLHSTRFIHR 509
Query: 390 DLRSANILV----GNGLICKIADFGLARLIE---DNEYTARQGAKFPIKWTAPEAALYGR 442
DL S NIL+ +G IADFGLA I D E G+ + W APE L G
Sbjct: 510 DLTSKNILIRREDNHGYHAVIADFGLATKIPDPLDKEKLPTVGSPY---WMAPE-VLNGH 677
Query: 443 F-TIKSDVWSFGILLTELVTKGRVP-----YPGMNNREVLEQVERGYRMPCPQDCPISLH 496
F ++D++S GI++ E+ R+P P MNN V + V + CP+
Sbjct: 678 FYNERADLFSVGIIMCEIT--ARIPADPDIMPRMNNFGV-DYVALSEMI---SYCPLDYL 839
Query: 497 ELMIHCWKKDPEERPTFEYLQSFLEDYF 524
+L C + DP++RP + +LE F
Sbjct: 840 QLAFKCCQVDPQKRPRGVEIIEWLEKIF 923
>17637
Length = 447
Score = 92.8 bits (229), Expect = 3e-19, Method: Compositional matrix adjust.
Identities = 46/132 (34%), Positives = 74/132 (56%), Gaps = 1/132 (0%)
Frame = +1
Query: 395 NILVGNGLICKIADFGLARLIEDNEYTARQGAKF-PIKWTAPEAALYGRFTIKSDVWSFG 453
N ++ + L K+ D L+R + +Y ++ PIKW + EA + SDVWSFG
Sbjct: 1 NCVIDDQLRVKLTDSALSRDLFSGDYNCLGDGEYRPIKWLSLEALQKSHYNEGSDVWSFG 180
Query: 454 ILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKKDPEERPTF 513
+L+ E+ T G++PY ++ E+ ++ GYR+ P +CP L +M +CW P ERP+F
Sbjct: 181 VLMWEMCTLGKLPYAEIDPYEMEHYLKDGYRLAQPFNCPDELFTIMAYCWASMPAERPSF 360
Query: 514 EYLQSFLEDYFT 525
LQ L ++ T
Sbjct: 361 SQLQICLSEFHT 396
>13592
Length = 980
Score = 91.3 bits (225), Expect = 9e-19, Method: Compositional matrix adjust.
Identities = 68/252 (26%), Positives = 131/252 (51%), Gaps = 17/252 (6%)
Frame = +2
Query: 276 RLGNGQFGEVWMGTWNGNTKV-AIK--TLKPG-TMSPESFLEEAQIMKKLKHDKLVQLYA 331
++G G+FG+V+ N ++ A+K ++PG T + ++ EE +I++ +KH LV+ Y
Sbjct: 5 KIGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETRALKNVAEELKILEGIKHKNLVRYYG 184
Query: 332 V-VSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVD--MAAQVAAGMAYIERMNYIH 388
+ V E + I E ++G+L ++ G LP + AQ+ +G+A + + +H
Sbjct: 185 IEVHREELLIFMELCSEGTLESLVELTGG----LPEALSRRFTAQLLSGVAELHKHGIVH 352
Query: 389 RDLRSANILVGNGL-ICKIADFGLARLIEDNE--------YTARQGAKFPIKWTAPEAAL 439
RD+++ANI + +G K+ DFG A I+ + Y Q P +T +
Sbjct: 353 RDIKTANIFLVDGSNSLKLGDFGSAVKIQAHTTVPGELQGYVGTQAYMAPEVFTKTNSDG 532
Query: 440 YGRFTIKSDVWSFGILLTELVTKGRVPYPGMN-NREVLEQVERGYRMPCPQDCPISLHEL 498
+GR +D+WS G ++ E+ + G+ P+ + N +++ +V G + P+ H+
Sbjct: 533 HGRL---ADIWSVGCVVVEMAS-GKRPWAQFDSNFQIMFKVGMGEKPQAPESLSQEGHDF 700
Query: 499 MIHCWKKDPEER 510
+ HC + DP++R
Sbjct: 701 IDHCLQHDPKQR 736
>14477
Length = 493
Score = 90.1 bits (222), Expect = 2e-18, Method: Composition-based stats.
Identities = 56/166 (33%), Positives = 94/166 (56%), Gaps = 9/166 (5%)
Frame = -1
Query: 269 ESLQLIK-RLGNGQFGEVWMGTWNGNTK---VAIKTLKPGTMSPE---SFLEEAQIMKKL 321
E +Q+ + +LG G FG V G + + VAIK LK + P ++EA++MKK+
Sbjct: 493 EQIQMDELKLGAGNFGSVMKGVCRLDDREIPVAIKVLKNADLDPSVQSELIKEAEVMKKM 314
Query: 322 KHDKLVQLYAVVSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYI 381
H +V+L + E + +V E G L FL + + L L N++++ QV+ GM Y+
Sbjct: 313 DHMHIVRLIGLCEGETMMLVLELAKLGPLNKFLP--KNKHLPLWNILELMWQVSQGMEYL 140
Query: 382 ERMNYIHRDLRSANILVGNGLICKIADFGLARLI--EDNEYTARQG 425
E ++HRDL + NIL+ + KI+DFG+++ + E+N Y A++
Sbjct: 139 EANKFVHRDLAARNILLCDEHFAKISDFGMSKTLSRENNYYMAQEA 2
>19301
Length = 712
Score = 89.4 bits (220), Expect = 3e-18, Method: Compositional matrix adjust.
Identities = 54/156 (34%), Positives = 88/156 (56%), Gaps = 3/156 (1%)
Frame = +2
Query: 258 VKTKDVWEIPRESLQLIKRLGNGQFGEVWMGTWNGNTKVAIKTLKPGTMSPESFLEEAQI 317
+K +D WEIP ES+ ++ LG+G G V++G +VA+K ++ ++E I
Sbjct: 272 LKQQDDWEIPFESITDLEWLGSGAQGAVFLGKLCAE-EVAVKKVRD--------IKETDI 424
Query: 318 --MKKLKHDKLVQLYAVVSEEPIY-IVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQV 374
++KL H ++ V ++ P Y I+ EY G L + L+DG+ L ++D + Q+
Sbjct: 425 RNLRKLNHPNIISFKGVCTQAPCYCIIMEYCPYGQLYEVLRDGKEIPPAL--VLDWSKQI 598
Query: 375 AAGMAYIERMNYIHRDLRSANILVGNGLICKIADFG 410
A+GM Y+ IHRDL+S N+LV + KI+DFG
Sbjct: 599 ASGMNYLHSHKIIHRDLKSPNVLVAKNDVVKISDFG 706
>13305
Length = 549
Score = 79.7 bits (195), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 35/102 (34%), Positives = 59/102 (57%), Gaps = 4/102 (3%)
Frame = +2
Query: 425 GAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYR 484
+ PI+W A E+ +T +SDVWSFG++L E+ T G PY + +++ ++ GYR
Sbjct: 2 STRVPIRWMAVESLFNNTYTTQSDVWSFGVVLWEIFTLGGTPYSSTDTQQLFAFLKDGYR 181
Query: 485 MPCPQDCPISLHELMIHCWKKDPEERPTFE----YLQSFLED 522
+ P+ C + + +M+ CW ++ + RPTF LQ L+D
Sbjct: 182 LKRPKLCDQNTYAMMLQCWNENAQRRPTFPELCGRLQRMLDD 307
>01756
Length = 1858
Score = 77.0 bits (188), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 59/214 (27%), Positives = 95/214 (44%), Gaps = 22/214 (10%)
Frame = -3
Query: 274 IKRLGNGQFGEVWMGTWNGNTKVAIKTLKPGTMS------PESFLEEAQIMKKLKHDKLV 327
+ ++G G FGEV+ +V +K M P + L E +I++ L H+ +V
Sbjct: 1727 LAKIGQGTFGEVFKARCKKTKQVV--AMKKVLMDNEKEGFPITALREIKILQLLNHENVV 1554
Query: 328 QLYAVVSEEP---------IYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGM 378
L + S + Y+V E+ L L LP + ++ Q+ G+
Sbjct: 1553 DLIEICSTKATSANRYKSMFYLVFEFCEHD--LAGLLSNMSVVFNLPEIKEVMKQLMNGL 1380
Query: 379 AYIERMNYIHRDLRSANILVGNGLICKIADFGLAR-----LIEDNEYTARQGAKFPIKWT 433
YI R +HRD+++ANIL+ + K+ADFGLAR L + N YT R W
Sbjct: 1379 YYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNR----VVTLWY 1212
Query: 434 APEAALYG--RFTIKSDVWSFGILLTELVTKGRV 465
P L G ++ D W G ++ E+ T+ +
Sbjct: 1211 RPPELLLGDRNYSTAIDQWGAGCIMAEMWTRNPI 1110
>00715
Length = 1788
Score = 76.6 bits (187), Expect = 3e-14, Method: Compositional matrix adjust.
Identities = 62/223 (27%), Positives = 103/223 (46%), Gaps = 31/223 (13%)
Frame = +1
Query: 321 LKHDKLVQLYAVVS----EEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAA 376
L+H +V + S E+ ++ EY+ +L L D + + + + +A Q+A
Sbjct: 97 LRHVNVVSILGATSLHRFEDGAWLAMEYVGPLNLQTILNDHQ-QDIDSSMRLSLALQMAR 273
Query: 377 GMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLI----------------EDNEY 420
G+ Y+ +N +H DL+ AN L+ L +IADFG + + E
Sbjct: 274 GLHYLHSINIVHLDLKPANCLLTRDLKLRIADFGCCHQLTPTGLDMGEREGGMAGNELEL 453
Query: 421 TARQGA-----KFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREV 475
T QGA + + APE + +++SDV+S GI L ++ T+ + PY G+ V
Sbjct: 454 TPVQGAWKNELAGTLAYRAPELLKGLQPSVRSDVYSLGITLWQMCTR-QGPYEGVPAHAV 630
Query: 476 LEQVERGYRMPCP----QDCP--ISLHELMIHCWKKDPEERPT 512
+ QV PCP +D P + +L CW + E+RPT
Sbjct: 631 VYQVVSKDLRPCPPPSTEDDPFEVMFRDLYTQCWARRVEDRPT 759
>12721
Length = 821
Score = 74.7 bits (182), Expect = 8e-14, Method: Compositional matrix adjust.
Identities = 54/226 (23%), Positives = 103/226 (45%), Gaps = 3/226 (1%)
Frame = +1
Query: 267 PRESLQLIKRLGNGQFGEVWMGTWNGNTKVAIKTLKPGTMSPESFL-EEAQIMKKLKHDK 325
PR L ++G G G V + T ++A+K + L E +M+ H
Sbjct: 82 PRTFLDDFMKIGEGSTGIVCIATSRDGRQMAVKKMDLRKQQRRELLFNEVVVMRDYHHPN 261
Query: 326 LVQLYA--VVSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIER 383
+V++Y +V++E +++V E+M G+L D + + +++ + + +A++
Sbjct: 262 IVEMYNSYLVNDE-LWVVMEFMEGGALTDIVTNNRMDEVQIATVCRACLK---ALAFLHA 429
Query: 384 MNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRF 443
IHRD++S +IL+ + K+ DFG + + + P W APE +
Sbjct: 430 NGVIHRDIKSDSILLSHDGKVKLXDFGFCAQVTQDLQKRKSLVGTPY-WMAPEVISRLPY 606
Query: 444 TIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQ 489
+ D+WS GI++ E++ P N L+ + R MP P+
Sbjct: 607 GPEVDIWSLGIMVMEMIDAE----PPFFNEPPLQAMRRIRDMPPPK 732
>18921
Length = 697
Score = 72.4 bits (176), Expect = 4e-13, Method: Compositional matrix adjust.
Identities = 51/201 (25%), Positives = 89/201 (44%), Gaps = 1/201 (0%)
Frame = +2
Query: 267 PRESLQLIKRLGNGQFGEVWMGTWNGNTKVAIKTLKPGTMSPESFLEEAQIMKKLKHDKL 326
P + ++ +LG G +G V+ +V P + ++E IM++ +
Sbjct: 23 PEDVFDILGKLGEGSYGSVFKSLHKETGQVLAIKQVPVDTDLQEIIKEISIMQQCDSKYI 202
Query: 327 VQLY-AVVSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMN 385
V+ Y + ++IV EY GS+ D ++ + L + + G+ Y+
Sbjct: 203 VKYYGSYFKNTDLWIVMEYCGAGSVSDIMRL-RNKTLVEREIATILYYTLKGLXYLHSRR 379
Query: 386 YIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTI 445
IHRD+++ NIL+ N K+ADFG+A + D P W APE +
Sbjct: 380 KIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTPY-WMAPEVIQEIGYDC 556
Query: 446 KSDVWSFGILLTELVTKGRVP 466
+D+WS GI E+ +G+ P
Sbjct: 557 VADIWSLGITALEM-AEGKPP 616
>01707
Length = 757
Score = 70.5 bits (171), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 63/222 (28%), Positives = 113/222 (50%), Gaps = 9/222 (4%)
Frame = +1
Query: 269 ESLQLIKRLGNGQFGEVWMGTWNGNTK-VAIKTLKPGTMSP---ESFLEEAQIMKKLKHD 324
E + I ++G G +G V+ ++ VAIK P + + E +++K+LKH
Sbjct: 64 EKYEKIGKIGEGSYGVVFKCRNKETSQLVAIKKFVESEDDPLIKKIAMREIRMLKQLKHP 243
Query: 325 KLVQLYAVVSEEP-IYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIER 383
LV+L V + +++V +Y++ +LL+ L D R L P + + Q + + +
Sbjct: 244 NLVRLIEVFRRKKRLHLVFDYVDH-TLLNEL-DRYPRGLPEPMVKRIIYQTLLAVNFCHQ 417
Query: 384 MNYIHRDLRSANILVGNGLICKIADFGLARLIE--DNEYTARQGAKFPIKWTAPEAALYG 441
N IHRD++ NIL+ K+ DFG AR++ +EYT ++ + APE L G
Sbjct: 418 YNTIHRDVKPENILITRQGQVKLCDFGFARILTGPGDEYTDYVATRW---YRAPE-LLVG 585
Query: 442 --RFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVER 481
++ DVW+ G + EL+T G+ +PG ++ + L + +
Sbjct: 586 DTQYGPPVDVWAIGCVFAELLT-GQALWPGRSDVDQLHLIRK 708
>17253
Length = 483
Score = 69.7 bits (169), Expect = 3e-12, Method: Composition-based stats.
Identities = 45/153 (29%), Positives = 69/153 (45%), Gaps = 16/153 (10%)
Frame = -1
Query: 296 VAIKTLKPGTMSPE--SFLEEAQIMKKL-KHDKLVQLYAVVS-EEPIYIVTEYMNKGSLL 351
VA+KT E FL E IM+KL +H +V + +P I+ E+ G LL
Sbjct: 459 VAVKTHNEAATDAEKSEFLRELSIMRKLPRHPNVVSFMGCCTMSDPALILMEFCCHGDLL 280
Query: 352 DFLKD----------GEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNG 401
FL+ L + A VA GMA++ +HRD+ + N+L+
Sbjct: 279 SFLRKRRPDRTVFLTSTANDLTARDFFSFALHVARGMAHVANNKIVHRDVAARNVLISER 100
Query: 402 LICKIADFGLARLIEDNE--YTARQGAKFPIKW 432
+CK++DFGL+R + D Y P++W
Sbjct: 99 NVCKVSDFGLSRRVGDQNDVYEIVSRRPLPLRW 1
>01060
Length = 1800
Score = 69.3 bits (168), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 61/253 (24%), Positives = 116/253 (45%), Gaps = 11/253 (4%)
Frame = +1
Query: 264 WEIPRESLQLIKRLGNGQFGEVWMGTWNGN-TKVAIKTLK---PGTMSPESFLEEAQIMK 319
+E L +++G G +G V+ K+A+K ++ P S + E +++
Sbjct: 58 FETALSDLTDFQKIGEGTYGVVYKCRHRATGRKLAMKKIRLRGSEDGVPSSAIREIAMLR 237
Query: 320 KLKHDKLVQLYAVVSE-EPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGM 378
+L+H +V L V+ E E +++V E+++ + K EG L + Q+ G+
Sbjct: 238 ELRHTNIVCLEDVIMEDERLFLVFEFLSMDLKMYIDKFPEGVVLDRRLVKSYVFQIVTGI 417
Query: 379 AYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAA 438
+ + +HRDL+ N+L+ + KIADFG+AR A + + APE
Sbjct: 418 XFCHQRRIVHRDLKPQNLLINHTGAIKIADFGMARTFA-LPVRAYTHEVVTLWYRAPEIL 594
Query: 439 L-YGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPISLHE 497
+ +++ DVWS G + +++ + + + G + + L ++ R P Q P H+
Sbjct: 595 MGASKYSTPVDVWSIGTIFADMLIRTPI-FKGDSEIDQLFKIFRIIGTPTEQTWP-EFHK 768
Query: 498 L-----MIHCWKK 505
L M WK+
Sbjct: 769 LPAFNGMFPLWKE 807
>00300
Length = 2318
Score = 67.8 bits (164), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 62/266 (23%), Positives = 124/266 (46%), Gaps = 16/266 (6%)
Frame = -1
Query: 276 RLGNGQFGEVWMGT-WNGNTKVAIKTLK--PGTMSP-ESFLEEAQIMKKLKHDKLVQLYA 331
++G GQFG+V+ + +A+K +K P + +E +I + ++H+ LV+ Y
Sbjct: 1637 KIGEGQFGKVYTAVNMSTGELMALKEMKFQPNDLQQLREMCDEIKIFEGIQHENLVKYYG 1458
Query: 332 V-VSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLV--DMAAQVAAGMAYIERMNYIH 388
V V ++ + + EY + G++ + K G LP + ++ + ++ + +H
Sbjct: 1457 VEVHKDEMLMFMEYCDTGTIEEAAKMG------LPEYLIRRYTREIVLAVNHLHENSIVH 1296
Query: 389 RDLRSANILVGNGLICKIADFGLARLIEDN-----EYTARQGAK---FPIKWTAPEAALY 440
RD++ ANI + + K+ DFG + ++ + E+ G P +T + Y
Sbjct: 1295 RDIKGANIFLTSNGHVKLGDFGCSVKLKSHTTMPGEFHNLVGTTAYMAPEVFTQNDQGGY 1116
Query: 441 GRFTIKSDVWSFGILLTELVTKGRVPYPGM-NNREVLEQVERGYRMPCPQDCPISLHELM 499
GR +D+WS G ++ E+ T G+ P+ + NN +++ +V G++ P + +
Sbjct: 1115 GR---AADIWSLGCVVIEMAT-GKRPWHDLDNNYQIMYKVGIGHKPAVPDSLSVEGKHFL 948
Query: 500 IHCWKKDPEERPTFEYLQSFLEDYFT 525
DP +R L L+ FT
Sbjct: 947 DLIMCHDPAQRALASQL---LDHTFT 879
>14126
Length = 1265
Score = 66.2 bits (160), Expect = 3e-11, Method: Compositional matrix adjust.
Identities = 59/236 (25%), Positives = 108/236 (45%), Gaps = 16/236 (6%)
Frame = +3
Query: 277 LGNGQFGEVWMG--TWNGNTKVAIKTLKPGTMS---PESFLEEAQIMKKLK---HDKLVQ 328
+GNG +G V+ N VA+K ++ P + E ++K+L+ H +V+
Sbjct: 213 IGNGAYGTVYKARDLRNQGEFVAMKRIRLNNTEEGMPMMAIREISMLKQLEQYEHPNVVR 392
Query: 329 LYAVV------SEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIE 382
L V E + +V EY+ + L +L L + D+ Q+ G+ ++
Sbjct: 393 LLDVSHNTITDREIRLNLVFEYI-EHDLATYLAKCPSPGLGPDRIKDLMLQLLNGVDFLH 569
Query: 383 RMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGR 442
+HRDL+ N+L+ K+ADFGLAR+ + + A + + +PE +
Sbjct: 570 SNRIVHRDLKPQNLLISKDGRLKLADFGLARIY--SFHMALTTVVVTLWYRSPEVLMQAE 743
Query: 443 FTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCP--ISLH 496
+ D+WS G + EL T+ R + G + + L+++ +P D P +S+H
Sbjct: 744 YGTSVDIWSCGCIFAELFTR-RALFKGSSEFDQLKKIFEVIGLPPAGDWPEGVSVH 908
>29581
Length = 1278
Score = 66.2 bits (160), Expect = 3e-11, Method: Compositional matrix adjust.
Identities = 59/191 (30%), Positives = 91/191 (47%), Gaps = 11/191 (5%)
Frame = -2
Query: 301 LKPGTMSPESFLEEAQIMKKLKHDKLVQLYAVV---SEEPIYIVTEYMNK--GSLLDFLK 355
L+ +SP + + L+H +VQL VV S + +++V EY + SLLD +
Sbjct: 1244 LERDMVSPSVVCVRSTFLLNLRHQNIVQLQEVVVGKSLDSLFLVMEYCEQDLASLLDNMP 1065
Query: 356 DGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLI 415
+ + + Q+ G+ Y+ IHRDL+ +N+L+ + KIADFGLAR
Sbjct: 1064 APFSES----QVKCIVLQLLKGLRYLHEAFIIHRDLKVSNLLMTDKGCVKIADFGLAR-- 903
Query: 416 EDNEYTARQGAKFP----IKWTAPEAALYGRFTIKS--DVWSFGILLTELVTKGRVPYPG 469
Y Q P + + APE L+G T + D+WS G +L EL+ P
Sbjct: 902 ---NYGKPQKPMTPKVVTLWYRAPE-LLFGSKTHSTAIDMWSAGCILGELLGHK----PL 747
Query: 470 MNNREVLEQVE 480
M R L+Q+E
Sbjct: 746 MPGRSDLQQIE 714
>18484
Length = 635
Score = 63.2 bits (152), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 37/122 (30%), Positives = 65/122 (53%)
Frame = +1
Query: 358 EGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIED 417
EG+ K P AA++A G+ ++ I+RDL+ N+++ + KIADFG+ +
Sbjct: 25 EGK-FKEPVAAFYAAEIAVGLFFLHDQGIIYRDLKLDNVMLDSEGHIKIADFGMCKEGMT 201
Query: 418 NEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLE 477
+ T R P + APE LY ++ D W++G+LL E++ G+ P+ G + E+
Sbjct: 202 GDATTRTFCGTP-DYIAPEIVLYQPYSKSVDWWAYGVLLFEMLA-GQPPFDGEDEDELFS 375
Query: 478 QV 479
+
Sbjct: 376 SI 381
>25550
Length = 941
Score = 63.2 bits (152), Expect = 3e-10, Method: Compositional matrix adjust.
Identities = 29/63 (46%), Positives = 41/63 (65%)
Frame = +3
Query: 465 VPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKKDPEERPTFEYLQSFLEDYF 524
V YPG++ EV +ERGYRM PQ P ++ LM+ CW+ DP+ERPTF+ + LE+ F
Sbjct: 36 VXYPGVDLTEVYHLLERGYRMERPQGTPADVYILMLKCWQWDPKERPTFKEIHYLLENMF 215
Query: 525 TAT 527
+
Sbjct: 216 EKS 224
>14420
Length = 528
Score = 61.6 bits (148), Expect = 7e-10, Method: Compositional matrix adjust.
Identities = 40/166 (24%), Positives = 80/166 (48%), Gaps = 3/166 (1%)
Frame = +2
Query: 309 ESFLEEAQIMKKLKHDKLVQ-LYAVVSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNL 367
E + E +M++ ++ +V L + + E +++V E++ GSL D + + + +
Sbjct: 35 ELIINEILVMRENQNPNIVNYLDSYLVGEELWVVMEFLAGGSLTDVVTE---TCMDEGQI 205
Query: 368 VDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLI--EDNEYTARQG 425
+ + + ++ IHRD++S NIL+G K+ DFG + E ++ + G
Sbjct: 206 AAVCRECLQALEFLHENQVIHRDIKSDNILLGMDGSVKLTDFGFCAQLSPEQSKRSTMVG 385
Query: 426 AKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMN 471
+ W APE ++ D+WS G++ E++ +G PY N
Sbjct: 386 TPY---WMAPEVVTRKQYGPTVDIWSLGVMCIEMI-EGEPPYLNEN 511
>27546
Length = 426
Score = 61.2 bits (147), Expect = 1e-09, Method: Composition-based stats.
Identities = 36/114 (31%), Positives = 56/114 (49%), Gaps = 7/114 (6%)
Frame = -1
Query: 311 FLEEAQIMKKLKHDKLVQLYAVVSEEP-IYIVTEYMNKGSLLDFLKDGEGRALKLPNLVD 369
F E +I+ +L H ++Q+++++ P I+I Y KG +L +K +D
Sbjct: 339 FPRELEILTRLDHPNIIQIHSILQRGPKIFIFMRYAEKGDMLSHIKK--------TGPID 184
Query: 370 MAA------QVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIED 417
A Q+A + Y+ + HRDL+ NIL+ L KIADFG AR D
Sbjct: 183 EAQTKVWFFQMAKALQYLHSHDIAHRDLKCENILLSKRLNVKIADFGFARYCRD 22
>04591
Length = 1117
Score = 60.8 bits (146), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 44/169 (26%), Positives = 83/169 (49%), Gaps = 14/169 (8%)
Frame = -2
Query: 308 PESFLEEAQIMKKLKHDKLVQLYAVVSEEP---------IYIVTEYMN--KGSLLDFLKD 356
P + L E +I+++L+H+ +VQL + + Y++ EY + LL+ L+
Sbjct: 1089 PITALREIKILQQLEHENVVQLQEICHTQAGPYNRYKSTFYLIFEYCDYDLAGLLNNLR- 913
Query: 357 GEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLAR-LI 415
L + ++ +Q+ G+ YI +HRD+++ANIL+ + K+ADFGL+R +
Sbjct: 912 ---VKFSLADKKNLMSQLLNGLFYIHTKQILHRDIKAANILLTRDGVLKLADFGLSRPWV 742
Query: 416 EDNEYTARQGAKFPIKWTAPEAALYG--RFTIKSDVWSFGILLTELVTK 462
+ T R W P L G + + D+W G ++ E+ ++
Sbjct: 741 KSKRLTNR----VVTLWYRPPELLLGEREYGPEIDMWGVGCIMAEMWSR 607
>00392
Length = 668
Score = 58.5 bits (140), Expect = 6e-09, Method: Compositional matrix adjust.
Identities = 53/174 (30%), Positives = 88/174 (50%), Gaps = 10/174 (5%)
Frame = +3
Query: 309 ESFLEEAQIMKKLKHDKLVQLYAVVSE------EPIYIVTEYMNKGSLLDFLKDGEGRAL 362
+ F EEA+++K+L+H +V+ + E + I +VTE M G+L +LK + +
Sbjct: 66 QRFKEEAEMLKELQHPNIVRFFDYWEEHNHRNRKVIILVTELMTSGTLKTYLKRFKKPNV 245
Query: 363 KLPNLVDMAAQVAAGMAYIERMN--YIHRDLRSANILV-GNGLICKIADFGLARLIEDNE 419
K+ L + QV G+ ++ IHRDL+ NI + G KI D GLA L N+
Sbjct: 246 KI--LKNWCRQVLKGLYFLHTRTPPVIHRDLKCDNIFITGPTGSVKIGDLGLATL--KNQ 413
Query: 420 YTARQGAKFPIKWTAPEAALY-GRFTIKSDVWSFGILLTELVTKGRVPYPGMNN 472
A+ P ++ APE +Y + DV++FG+ + E+ + PY +N
Sbjct: 414 SFAKSVIGTP-EFMAPE--MYEEHYDEAVDVYAFGMCMLEMAS-SEYPYSECSN 563
>11228
Length = 2155
Score = 58.2 bits (139), Expect = 8e-09, Method: Compositional matrix adjust.
Identities = 41/149 (27%), Positives = 75/149 (50%), Gaps = 5/149 (3%)
Frame = -2
Query: 88 VALYDYEARTE-DDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYVAPVDS--- 143
VA+ Y T+ D+LSF KG+ F + N E W T E+G +P+ +V +D
Sbjct: 1662 VAMLSYRKATDSDELSFCKGDVFVVQNEMEDGWLWVTCERTKESGLVPAPFVKDLDGDYE 1483
Query: 144 -IQAEEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDWDDMKGDHVKH 202
+++ ++ L +++A +L+ G G+FL+R+SE G YSL D V+
Sbjct: 1482 PVESLPYFHSCLSKEEAVEKLMLAGE--GSFLVRQSENYPGDYSLFFLCEKD-----VRR 1324
Query: 203 YKIRKLDNGGYYITTRAQFETLQQLVQHY 231
++I + G ++ F++L +++ Y
Sbjct: 1323 FRIER--RGNQFLVGGRLFDSLDGVIKRY 1243
Score = 37.0 bits (84), Expect = 0.018, Method: Compositional matrix adjust.
Identities = 22/57 (38%), Positives = 31/57 (54%)
Frame = -1
Query: 132 YIPSNYVAPVDSIQAEEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLS 188
+I S AP + WY G+LGR AE L G++L+RESE+ G++ LS
Sbjct: 2011 HINSALTAPDQKL----WYHGRLGRAGAEELLRD--QDAGSYLVRESESKLGSFVLS 1859
>01966
Length = 1735
Score = 58.2 bits (139), Expect = 8e-09, Method: Compositional matrix adjust.
Identities = 32/107 (29%), Positives = 58/107 (54%), Gaps = 1/107 (0%)
Frame = -1
Query: 308 PESFLEEAQIMKKLKHDKLVQLYAVVSE-EPIYIVTEYMNKGSLLDFLKDGEGRALKLPN 366
P S + E ++++L+H +V L V+ E E +++V E+++ + K EG L
Sbjct: 1582 PSSAIREIAMLRELRHTNIVCLEDVIMEDERLFLVFEFLSMDLKMYIDKFPEGVVLDRRL 1403
Query: 367 LVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLAR 413
+ Q+ G+ + + +HRDL+ N+L+ + KIADFG+AR
Sbjct: 1402 VKSYVFQIVTGINFCHQRRIVHRDLKPQNLLINHTGAIKIADFGMAR 1262
>09606
Length = 1300
Score = 57.8 bits (138), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 53/224 (23%), Positives = 95/224 (42%), Gaps = 23/224 (10%)
Frame = -3
Query: 269 ESLQLIKRLGNGQFGEVWMGTWNGNTK-VAIKTLKPGTMSPESFLEEAQIMKKLKHDKLV 327
E+ L + LG G+ ++ G G VAI ++ PE ++ + H +V
Sbjct: 1115 ENFVLYEELGKGEHSIIYKGRRKGTINFVAIHCIEK-CKRPE-VTNTVRMTHDISHPNVV 942
Query: 328 QLYA-VVSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNY 386
Q + + +++V E GSL D L + L ++ D + G+ YI +
Sbjct: 941 QFHEWYETSNHLWLVVELCTGGSLADIL--AQDHHLPETSIRDFGIHLVTGLHYIHSLGI 768
Query: 387 IHRDLRSANILVGNGLICKIADFGLARLIEDNEYT-----ARQGAKFPIK---------- 431
+ DLR + +L+ + K ADFGL+++ +N A G ++ I+
Sbjct: 767 LFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQWNIQSAEEMMKQVP 588
Query: 432 ------WTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPG 469
+ APE +I SD+W+ G + E+ + G P+ G
Sbjct: 587 TSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFS-GHPPFLG 459
>03240
Length = 1683
Score = 57.0 bits (136), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 47/162 (29%), Positives = 77/162 (47%), Gaps = 9/162 (5%)
Frame = -3
Query: 274 IKRLGNGQFGEVWMGTWNGNTKV-AIKTLKPGTMSPESFLE----EAQIMKKLKHDKLVQ 328
IK LG G FGEV + N + A+KTL+ + + + E I+ + ++ +V+
Sbjct: 1276 IKTLGVGAFGEVSLCRKNDTGMLYAMKTLRKSDVLKRNQVAHVKAERDILAEADNEWVVK 1097
Query: 329 LYAVVSEEP-IYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYI 387
LY + +Y V +Y+ G L+ L E L P A++ + + RM +I
Sbjct: 1096 LYYSFQDHNYLYFVMDYVPGGDLMGLLIRME--ILDEPLARFYVAELVQAIESVHRMGFI 923
Query: 388 HRDLRSANILVGNGLICKIADFGLA---RLIEDNEYTARQGA 426
HRD++ NIL+ K+ DFGL R +++Y R G
Sbjct: 922 HRDIKPDNILIDRNGHIKLTDFGLCTGFRWTHNSKYYQRDGT 797
>31885
Length = 529
Score = 57.0 bits (136), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 46/169 (27%), Positives = 78/169 (46%), Gaps = 6/169 (3%)
Frame = -2
Query: 315 AQIMKKLKHDKLVQL-YAVVSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQ 373
++ +L H LV L YA EE +++V + G L ++ + + + + Q
Sbjct: 519 VDMLTRLDHPFLVNLWYAFQDEEDLFMVVDLFLGGDLRYHMQ--QEVSFREDCVKFYLCQ 346
Query: 374 VAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWT 433
+A + Y+ +HRD++ NIL+ C + DF +A +ED+E P +
Sbjct: 345 LALVLDYLRSQKIVHRDIKPDNILLDEQGHCHVTDFNIATQLEDDELATSTSGTRP--YM 172
Query: 434 APE---AALYGR--FTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLE 477
APE A+ R + D WS G+ L EL+ K R P+ +N + E
Sbjct: 171 APEVYGVAINERRGYGFPVDWWSLGVSLFELLKKRR-PFSVHSNTSLHE 28
>07836
Length = 1478
Score = 56.6 bits (135), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 62/217 (28%), Positives = 100/217 (46%), Gaps = 42/217 (19%)
Frame = -1
Query: 338 IYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIE--------RMNYIHR 389
++++T+Y GSL D+L R L ++ +A G+A++ + HR
Sbjct: 1328 LFLITDYHENGSLHDYLL---SRVLDSSEMLALAHSAICGLAHLHIEIFGTRGKPAIAHR 1158
Query: 390 DLRSANILVGNGLICKIADFGLA-RLI-EDNEYTA----RQGAKFPIKWTAPEAALYGRF 443
D++S NILV C IAD GLA R I E NE RQG K ++ APE L
Sbjct: 1157 DIKSKNILVKKNGTCCIADLGLAVRYISESNEVDVAPNPRQGTK---RYMAPE-VLEMLL 990
Query: 444 TIK-------SDVWSFGILLTEL----VTKG-----RVPY-------PGMNNREVLEQVE 480
+K +D+++FG+++ E+ V G +VP+ P + ++ V+
Sbjct: 989 NVKNFDAFKQADMYAFGLVMWEIARCCVIGGVAEEYQVPFYNCLPHDPSFEDVRLVVSVD 810
Query: 481 RGYRMPCP---QDCPI--SLHELMIHCWKKDPEERPT 512
+ R P Q+ PI + ++M CW +P R T
Sbjct: 809 K-VRPDIPLRWQEDPIMKVMVKVMCECWSGNPAARLT 702
>13066
Length = 551
Score = 56.2 bits (134), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 47/181 (25%), Positives = 80/181 (44%), Gaps = 12/181 (6%)
Frame = +3
Query: 285 VWMGTWNG----NTKVAIKTL----KPGTMSPESFLEEAQIMKKLKHDKLVQLYAVVSEE 336
V GT+N N K+A K + P + F E ++ KL H ++Q+++++
Sbjct: 15 VVHGTFNDGYGRNIKLACKIIDKEKAPVDFVEKFFPRELDLLTKLDHPYIIQIHSILQRX 194
Query: 337 PI-YIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSAN 395
P +I + +G LL +++ E +K Q+ + Y+ + HRDL+ N
Sbjct: 195 PKNFIFMRFAERGDLLTYIQ--EVGFVKEKQAKIWFYQMTTALNYLHSYDVAHRDLKCEN 368
Query: 396 ILVGNGLICKIADFGL--ARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIK-SDVWSF 452
IL+ + K+ADFG A + E E + + APE + K +D WS
Sbjct: 369 ILLSSHFNVKLADFGFACACITESGEKYMSRTYCGSAAYAAPEIVYGAPYAPKVADAWSL 548
Query: 453 G 453
G
Sbjct: 549 G 551
>12672
Length = 773
Score = 53.9 bits (128), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 40/164 (24%), Positives = 74/164 (45%), Gaps = 16/164 (9%)
Frame = +3
Query: 375 AAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPI---K 431
A+G+ Y+ ++HRD+++ANIL+ + K+ DF E Q A I
Sbjct: 21 ASGIQYLNDNGHVHRDIKTANILLDSEYTAKVGDFATVVSAPSGEGKTVQNASVVIGTAA 200
Query: 432 WTAPEAALYGRFTIKSDVWSFGILLTELVT----------KGRVPYPGMNNREVLEQVER 481
+ APE A++ + K D +SFG++L E++T + + M N E E++
Sbjct: 201 YLAPE-AIHFDVSTKLDSYSFGVVLLEVITGLVAQDYSREERTLSSHIMENVEEPEEIHD 377
Query: 482 GYRMPC---PQDCPISLHELMIHCWKKDPEERPTFEYLQSFLED 522
P L+++ + C ++RP + ++ LE+
Sbjct: 378 FVDQSAGTWPDGAVDKLYDISMRCLNLSKKQRPNVKDIRPELEE 509
>13212
Length = 1067
Score = 52.8 bits (125), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 45/167 (26%), Positives = 76/167 (45%), Gaps = 11/167 (6%)
Frame = -1
Query: 373 QVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKF---P 429
++ + ++ R + IHRD+++ N+L+ K+ADFG++ N T ++ F P
Sbjct: 956 EMCMALDFLHRHHVIHRDIKAGNVLLTIDGEVKLADFGVSA---KNTQTQQKRDTFIGTP 786
Query: 430 IKWTAPEAALY-----GRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERG-- 482
W APE L + K+D+WS G+ L E + P M+ VL ++ +
Sbjct: 785 Y-WMAPEVVLCETLKDTPYDFKADIWSLGVTLIEFA-QIEPPNKEMHPMRVLIKIHKSDP 612
Query: 483 YRMPCPQDCPISLHELMIHCWKKDPEERPT-FEYLQSFLEDYFTATE 528
+ P+ + + C KDP RPT E L+ TAT+
Sbjct: 611 PTLEKPKKWTKLFKDFIAKCLVKDPNLRPTAAELLEHPFMKRATATD 471
>04138
Length = 800
Score = 52.4 bits (124), Expect = 5e-07, Method: Compositional matrix adjust.
Identities = 32/95 (33%), Positives = 48/95 (50%), Gaps = 7/95 (7%)
Frame = +1
Query: 378 MAYIERMNYIHRDLRSANILVGNGLICKIADFGLAR-----LIEDNEYTARQGAKFPIKW 432
+ YI R +HRD+++ANIL+ + K+ADFGLAR L + N YT R W
Sbjct: 52 LYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNR----VVTLW 219
Query: 433 TAPEAALYG--RFTIKSDVWSFGILLTELVTKGRV 465
P L G ++ D W G ++ E+ T+ +
Sbjct: 220 YRPPELLLGDRNYSTAIDQWGAGCIMAEMWTRNPI 324
>21079
Length = 878
Score = 51.6 bits (122), Expect = 8e-07, Method: Compositional matrix adjust.
Identities = 39/143 (27%), Positives = 69/143 (48%), Gaps = 4/143 (2%)
Frame = +1
Query: 323 HDKLVQLY-AVVSEEPIYIVTEYMNKGSLLD-FLKDGEGRALKLPNLVDMAAQVAAGMAY 380
H KL+ L+ A + + +V E++ G L + ++D L + V Q+ +G+ Y
Sbjct: 1 HPKLLMLWDAFEAPRTMVLVMEFVGAGELFERVIRDD--FVLTERDCVHFVRQICSGVGY 174
Query: 381 IERMNYIHRDLRSANILV--GNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAA 438
+ + +H DL+ N+L N KI DFGLAR + + + Q ++ APE
Sbjct: 175 MHTQSILHLDLKPENVLCVSDNSNQIKIIDFGLARFYKPGD--SLQVLFGTPEFIAPEVV 348
Query: 439 LYGRFTIKSDVWSFGILLTELVT 461
Y +D+WS G++ L++
Sbjct: 349 NYDEINFTTDMWSIGVICYILLS 417
>29243
Length = 1147
Score = 51.2 bits (121), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 32/98 (32%), Positives = 51/98 (52%), Gaps = 2/98 (2%)
Frame = +2
Query: 136 NYVAPVDSIQAEEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETT--KGAYSLSIRDWD 193
+YV S+++ WY G + R A++ L + P GTFLIR + +G SLSI+
Sbjct: 269 DYVNEPCSLESYNWYVGIMERPVAQKXLDTC--PDGTFLIRVTNNPLRRGELSLSIK--- 433
Query: 194 DMKGDHVKHYKIRKLDNGGYYITTRAQFETLQQLVQHY 231
+ V+H K+ + G +Y+ F+ +Q LV HY
Sbjct: 434 --YANAVRHIKVNRNPQGRFYLADGRYFDNIQSLVDHY 541
Score = 40.4 bits (93), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 21/58 (36%), Positives = 30/58 (51%), Gaps = 2/58 (3%)
Frame = +2
Query: 88 VALYDYEARTEDDLSFHKGEKFQIL--NSSEGDWWEARSLTTGETGYIPSNYVAPVDS 143
VA+YDY A + LS ++ IL N + WW+ +L T + GY P YV D+
Sbjct: 641 VAVYDYAATSTSQLSMKLNDRIAILSKNGQDKGWWKGENLRTQKIGYFPLAYVDEEDA 814
>12324
Length = 946
Score = 48.9 bits (115), Expect = 5e-06, Method: Compositional matrix adjust.
Identities = 22/53 (41%), Positives = 32/53 (60%)
Frame = +3
Query: 88 VALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYVAP 140
VA+YDYEA +D+L+F + ++ ++ WWE + G TG PSNYV P
Sbjct: 699 VAIYDYEAEKDDELTFSENSVIYVIRKNDDGWWEG--VMDGVTGLFPSNYVEP 851
>19094
Length = 898
Score = 48.5 bits (114), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 28/83 (33%), Positives = 41/83 (49%)
Frame = +1
Query: 377 GMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPE 436
G+ Y+ IHRD+++ NIL+ N K+ADFG+A + D P W APE
Sbjct: 94 GL*YLHSRRKIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTP-YWMAPE 270
Query: 437 AALYGRFTIKSDVWSFGILLTEL 459
+ +D+WS GI E+
Sbjct: 271 VIQEIGYDCVADIWSLGITALEM 339
>30755
Length = 1137
Score = 47.8 bits (112), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 37/142 (26%), Positives = 66/142 (46%), Gaps = 2/142 (1%)
Frame = +2
Query: 371 AAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEY--TARQGAKF 428
A++ + + Y+ I+RDL+ N+L+ K+ADFGL + ED Y T +
Sbjct: 50 GAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCK--EDITYGRTTKTFCGT 223
Query: 429 PIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCP 488
P ++ APE + D W G+++ E++ GR+P+ + +VL + + P
Sbjct: 224 P-EYLAPEVLDDNDYGRAVDWWGTGVVMYEMIC-GRLPFYN-RDHDVLFTLILVEDVKFP 394
Query: 489 QDCPISLHELMIHCWKKDPEER 510
++ L+ KDP R
Sbjct: 395 RNITDEAKSLLSGLLAKDPRNR 460
>15910
Length = 1361
Score = 47.8 bits (112), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 34/114 (29%), Positives = 57/114 (50%), Gaps = 3/114 (2%)
Frame = +2
Query: 372 AQVAAGMAYIERMNYIHRDLRSANIL---VGNGLICKIADFGLARLIEDNEYTARQGAKF 428
+ + G+ YI +HRDL+ N+L + + K+ADFGL+R+IE E
Sbjct: 485 SDILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLADFGLSRIIEP-EVQMSTVCGT 661
Query: 429 PIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERG 482
P + APE ++T D+WS G++ L+ G P+ N E+ ++ +G
Sbjct: 662 P-GYCAPEVLKGDKYTPSVDMWSVGVIAYILLC-GYEPFFAENEFEMYRKIIKG 817
>26560
Length = 398
Score = 46.6 bits (109), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 32/103 (31%), Positives = 52/103 (50%), Gaps = 1/103 (0%)
Frame = -1
Query: 371 AAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPI 430
AA+V G+ ++ ++RDL+ ANIL+ +I+D GLA A G
Sbjct: 338 AAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGLACDFSKKRPHASVGTH--- 168
Query: 431 KWTAPEAALYGR-FTIKSDVWSFGILLTELVTKGRVPYPGMNN 472
+ APE + G+ + +D +SFG +L +L+ KG P+ N
Sbjct: 167 GYMAPEVLMKGQSYDSSADWFSFGCMLYKLL-KGHSPFRQHNQ 42
>21210
Length = 518
Score = 45.8 bits (107), Expect = 5e-05, Method: Compositional matrix adjust.
Identities = 34/86 (39%), Positives = 47/86 (54%), Gaps = 4/86 (4%)
Frame = +3
Query: 435 PEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPG-MNNREVLEQVERGYRMPC-PQDCP 492
P A+ +G + ++SDVWS GI L EL T GR PY ++ + L+QV RG PC P D
Sbjct: 42 PRASSHG-YDVRSDVWSLGITLMELAT-GRFPYRKWVSIFDQLQQVVRGV-APCLPHDGA 212
Query: 493 IS--LHELMIHCWKKDPEERPTFEYL 516
S + C KD ++RP + L
Sbjct: 213 FSHDFVNFVNKCLTKDEKQRPKYNKL 290
>14257
Length = 919
Score = 45.4 bits (106), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 33/105 (31%), Positives = 52/105 (49%), Gaps = 5/105 (4%)
Frame = -3
Query: 147 EEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDWDDMKGDHVKHYKIR 206
EEWY GK+GRK+AE+ L G FL+RE+ + + LS R + +V+H +
Sbjct: 896 EEWYHGKIGRKEAEKLL----ELDGDFLVREASNSAAQFVLSGR-----QNGNVRHLLL- 747
Query: 207 KLDNGGYYITTRAQFETLQQLVQHYSERA-----AGLCCRLVVPC 246
+D G T F+++ L+ ++ + A G RLV P
Sbjct: 746 -VDPDGIVRTKDFIFDSVSHLINYHRQNALPIITEGSELRLVRPI 615
>19761
Length = 473
Score = 45.1 bits (105), Expect = 7e-05, Method: Compositional matrix adjust.
Identities = 34/119 (28%), Positives = 54/119 (45%), Gaps = 3/119 (2%)
Frame = -3
Query: 373 QVAAGMAYIERMN--YIHRDLRSANILVGNGLICKIADFGLAR-LIEDNEYTARQGAKFP 429
Q A+ + Y+ +HRDL+ NI V ++ D GLAR L ++ Q
Sbjct: 399 QTASALNYMHTHTPVILHRDLKPQNIYVTEKGDVRLGDLGLARKLTGPADFATSQVGT-- 226
Query: 430 IKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCP 488
I + +PE + KSD+WS G + ++ G+ M +L QV G ++P P
Sbjct: 225 IMYLSPEILSQQPYNSKSDIWSLGCVFYDIT--GKKGSDEMGVMFLLVQVMGGRKLPLP 55
>29687
Length = 434
Score = 45.1 bits (105), Expect = 8e-05, Method: Compositional matrix adjust.
Identities = 22/55 (40%), Positives = 32/55 (58%)
Frame = -2
Query: 89 ALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYVAPVDS 143
AL+DY A+ ED+LSF KG ++ +G WW T + + PSNYV +D+
Sbjct: 286 ALHDYNAKREDELSFCKGAIITNVSRQDGGWWRG-DYGTKKQHWFPSNYVEEIDT 125
>11185
Length = 473
Score = 44.3 bits (103), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 35/142 (24%), Positives = 61/142 (42%), Gaps = 25/142 (17%)
Frame = +1
Query: 369 DMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYT-----AR 423
D + G+ YI + + DLR + +L+ + K ADFGL+++ +N A
Sbjct: 13 DFGIHLVTGLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAE 192
Query: 424 QGAKFPIK----------------WTAPEAALYGRFTIKSDVWSFGILLTELVTKGRV-- 465
G ++ I+ + APE +I SD+W+ G + E+ + R+
Sbjct: 193 AGDQWNIQSAEEMMKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSGSRLSA 372
Query: 466 -PYPG-MNNREVLEQVERGYRM 485
P P +N E L Q + R+
Sbjct: 373 KPSPEFLNLLESLLQKDSTRRL 438
>16708
Length = 1397
Score = 42.4 bits (98), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 36/155 (23%), Positives = 78/155 (50%), Gaps = 11/155 (7%)
Frame = -1
Query: 271 LQLIKRLGNGQFGEVWMG-TWNGNTKVAIKTLKPGTMSPESFLEEAQIMKKLKHD-KLVQ 328
+ +++ LG G FG+V+ + + K A+KT ++ L+E + + +++ L Q
Sbjct: 1397 VAILQVLGKGVFGKVYEARLLSTHEKAALKT----SILCHHSLDEVEALGRIEGGFYLAQ 1230
Query: 329 LY-AVVSEEP---IYIVTEYMNKGSLLDFLKDGEGRALKL----PNLVD-MAAQVAAGMA 379
++ A V+ P + I+ + G L + + + + + P +V +A Q +
Sbjct: 1229 MFGAWVTCLPFPKMNILLHFYEMGPLCNVYAHYKNKEMPIRWSNPAMVCCIAGQXVCALE 1050
Query: 380 YIERMNYIHRDLRSANILVGNGLICKIADFGLARL 414
+I + +H D+++ N+LV CK+ D+G+A+L
Sbjct: 1049 HIHELGVVHMDVKADNVLVDAHGNCKLTDYGIAQL 945
>28638
Length = 1458
Score = 42.0 bits (97), Expect = 6e-04, Method: Compositional matrix adjust.
Identities = 35/109 (32%), Positives = 53/109 (48%), Gaps = 5/109 (4%)
Frame = -1
Query: 358 EGRALKLPNLVDMAAQVAAGMAYIE--RMNYIHRDLRSANILVGN---GLICKIADFGLA 412
EG +L L A Q+ + ++ MN IH DL+ NIL+ N I KI DFG +
Sbjct: 852 EGVSLNLTR--KFAQQLCTALLFLATPEMNIIHCDLKPENILLCNPKRSAI-KIVDFGSS 682
Query: 413 RLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVT 461
+ Y Q ++F + +PE L + + D+WS G +L E+ T
Sbjct: 681 CQLGQRIYQYIQ-SRF---YRSPEVLLGVPYDLAIDMWSLGCILVEMHT 547
>28095
Length = 597
Score = 41.6 bits (96), Expect = 8e-04, Method: Compositional matrix adjust.
Identities = 19/50 (38%), Positives = 28/50 (56%)
Frame = +3
Query: 89 ALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYV 138
A+YDY+A D++SF+ G+ + W R TG+ G +PSNYV
Sbjct: 270 AMYDYQAADSDEVSFNDGDTIIECQPVDAGWMTGRVERTGQYGMLPSNYV 419
>26711
Length = 405
Score = 41.2 bits (95), Expect = 0.001, Method: Composition-based stats.
Identities = 31/111 (27%), Positives = 54/111 (48%), Gaps = 3/111 (2%)
Frame = -2
Query: 373 QVAAGMAYIERMNYIHRDLRSANILVGNGLI--CKIADFGLAR-LIEDNEYTARQGAKFP 429
QV + ++ +H DL+ +N+L+ + ++ DFGLAR L E G
Sbjct: 392 QVLDILQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARKLYPPQETFLNHGTP-- 219
Query: 430 IKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVE 480
+T+PEA + SDVW G+L L++ G+ P+ + E L++ +
Sbjct: 218 -GFTSPEALDVKPISTASDVWGVGVLAYILLS-GQSPFQADSATESLKKTQ 72
>12786
Length = 460
Score = 41.2 bits (95), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 27/107 (25%), Positives = 51/107 (47%), Gaps = 21/107 (19%)
Frame = -3
Query: 387 IHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPI-KWTAPEAALYG---- 441
IH DL+ AN ++ G + K+ DFG+A ++ ++ + + ++ + +PEA +
Sbjct: 344 IHSDLKPANFMLVAGNL-KLIDFGIANTLQQDKTSVLKDSRVGTPSYMSPEAIMAACDDS 168
Query: 442 ----------------RFTIKSDVWSFGILLTELVTKGRVPYPGMNN 472
+ ++SDVWS G +L +V GR P+ + N
Sbjct: 167 ADDSMEEDGHRTKPKYKVGVRSDVWSLGCILYNMVY-GRTPFQHIKN 30
>05206
Length = 1075
Score = 40.8 bits (94), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 19/50 (38%), Positives = 27/50 (54%)
Frame = +1
Query: 89 ALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYV 138
ALY +EA E + + E+ QIL +GD W G G++PS+YV
Sbjct: 103 ALYPFEAMNEGSVPMGENEEMQILEEDQGDGWTRVRKADGSEGFVPSSYV 252
>01494
Length = 2122
Score = 40.4 bits (93), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 30/107 (28%), Positives = 49/107 (45%), Gaps = 5/107 (4%)
Frame = +3
Query: 89 ALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYVAPVDS---IQ 145
AL+DY A +D+LSF KG ++ +G WW + + PSN+V +++ +
Sbjct: 318 ALHDYNANRDDELSFCKGAIITNVSRQDGGWWRG-DYGAKKQHWFPSNFVEEIETHSDVN 494
Query: 146 AEEWYFGKL--GRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIR 190
++ G L G D + L+ PRG K A+ +S R
Sbjct: 495 SDSMPLGSLQQGSFDIQGCLVEPLAPRG---------DKSAFRISTR 608
>37602
Length = 804
Score = 40.4 bits (93), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 23/77 (29%), Positives = 37/77 (48%)
Frame = -1
Query: 333 VSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLR 392
+ E ++I EY GS+ D L P + + + G+ Y+ R +HRD++
Sbjct: 309 LRREKLWIAMEYCGGGSMQDIYH--VTGPLTEPQIAFVCRETLKGLHYLHRRGKMHRDIK 136
Query: 393 SANILVGNGLICKIADF 409
ANIL+ K+ADF
Sbjct: 135 GANILLTEEGDVKLADF 85
>06462
Length = 1511
Score = 40.4 bits (93), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 32/119 (26%), Positives = 48/119 (40%)
Frame = +1
Query: 133 IPSNYVAPVDSIQAEEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDW 192
+PS+ D E WY GK+ R++AE+ L G FL+RES + LS +
Sbjct: 1048 MPSSETGVTDPPLHELWYHGKMSRREAEKLL----GKDGDFLVRESGHNXSQFVLSGK-- 1209
Query: 193 DDMKGDHVKHYKIRKLDNGGYYITTRAQFETLQQLVQHYSERAAGLCCRLVVPCHKGMP 251
H + + +D G T F+ + LV ++ CH GMP
Sbjct: 1210 -----HHGQFIHLLLVDPDGIVRTKDYIFDNISHLVSYH--------------CHHGMP 1329
>32000
Length = 644
Score = 39.7 bits (91), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 28/83 (33%), Positives = 43/83 (51%), Gaps = 1/83 (1%)
Frame = -1
Query: 405 KIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRF-TIKSDVWSFGILLTELVTKG 463
KIADFGLAR+ T + + APE L RF ++ D+WS G + E++T+
Sbjct: 569 KIADFGLARVFGLPVRTYTHEV-ITLWYRAPEILLGCRFYSVPVDIWSLGCIFVEMMTR- 396
Query: 464 RVPYPGMNNREVLEQVERGYRMP 486
R +PG + + L ++ R P
Sbjct: 395 RALFPGDSEIDQLYRIFRTLGTP 327
>18481
Length = 437
Score = 39.7 bits (91), Expect = 0.003, Method: Composition-based stats.
Identities = 21/65 (32%), Positives = 37/65 (56%), Gaps = 3/65 (4%)
Frame = -1
Query: 360 RALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICK---IADFGLARLIE 416
R L ++ ++ Q+ + + +I + +IHRDL+ N L+G G C I DFGL++ +
Sbjct: 212 RRFTLKTILMVSDQLLSRLEFIHQKCFIHRDLKPDNFLMGLGRHCHRLYIIDFGLSKRYK 33
Query: 417 DNEYT 421
D + T
Sbjct: 32 DTQGT 18
>32264
Length = 287
Score = 39.3 bits (90), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 18/44 (40%), Positives = 29/44 (65%)
Frame = +1
Query: 479 VERGYRMPCPQDCPISLHELMIHCWKKDPEERPTFEYLQSFLED 522
+E GYR+ P S+++LM+ CW+ PE+RP F+ L + L+D
Sbjct: 1 IEDGYRLQQNPQTPDSVYKLMLRCWEYVPEKRPHFKELYTSLKD 132
>35671
Length = 567
Score = 38.5 bits (88), Expect = 0.007, Method: Compositional matrix adjust.
Identities = 15/47 (31%), Positives = 28/47 (59%)
Frame = -3
Query: 480 ERGYRMPCPQDCPISLHELMIHCWKKDPEERPTFEYLQSFLEDYFTA 526
++G R+ P C +++M+ CW + EERPTF+ L +E+ + +
Sbjct: 565 QKGNRLAKPISCTDEAYKVMLQCWTESREERPTFKKLVPVMENLYRS 425
>16716
Length = 934
Score = 37.7 bits (86), Expect = 0.012, Method: Compositional matrix adjust.
Identities = 28/111 (25%), Positives = 44/111 (39%)
Frame = -1
Query: 28 YRYGTDPTPQHYPSFGVTSIPNYNNFHAAGGQGLTVFGGVNSSSHXXXXXXXXXXXXXXF 87
Y +P PQH P + + A Q GG +++
Sbjct: 577 YEVSEEPAPQHEPEESPYEMADEEPAAPAQSQP----GGGSTA----------------- 461
Query: 88 VALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYV 138
+ALYDY+A +D+L+F + + + WW R G+ G P+NYV
Sbjct: 460 IALYDYQAADDDELTFDPDDVITDIEMIDDGWW--RGSCHGKNGLFPANYV 314
>17286
Length = 489
Score = 37.4 bits (85), Expect = 0.014, Method: Compositional matrix adjust.
Identities = 17/56 (30%), Positives = 31/56 (55%)
Frame = +3
Query: 89 ALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYVAPVDSI 144
A+YD+ ++ +L F +G+ +++ + +W+E G+ GY P NYV V I
Sbjct: 36 AIYDFLPESDGELGFQEGDMITLISQVDENWFEGS--VHGKVGYFPINYVEVVVPI 197
>27405
Length = 532
Score = 37.4 bits (85), Expect = 0.014, Method: Compositional matrix adjust.
Identities = 32/121 (26%), Positives = 52/121 (42%)
Frame = -3
Query: 330 YAVVSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHR 389
YA + E + + + MN G L L + + AA+V G+ ++ ++R
Sbjct: 353 YAFQTPEKLCFILDLMNGGDLHYHLS--QHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYR 180
Query: 390 DLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDV 449
DL+ ANIL+ +I+D GLA + A G + APE + G+ S
Sbjct: 179 DLKPANILLDENGHVRISDLGLACDFSKKKPHASVGTH---GYMAPEVLMKGQAYDSSAD 9
Query: 450 W 450
W
Sbjct: 8 W 6
>30740
Length = 488
Score = 37.4 bits (85), Expect = 0.017, Method: Compositional matrix adjust.
Identities = 13/33 (39%), Positives = 21/33 (63%)
Frame = +2
Query: 91 YDYEARTEDDLSFHKGEKFQILNSSEGDWWEAR 123
YD+ R +DL F KG+ ++++ E +WW AR
Sbjct: 203 YDFSGRDPEDLPFSKGDILELISKDEEEWWTAR 301
>38046
Length = 446
Score = 36.6 bits (83), Expect = 0.023, Method: Composition-based stats.
Identities = 15/26 (57%), Positives = 20/26 (76%)
Frame = -1
Query: 374 VAAGMAYIERMNYIHRDLRSANILVG 399
+A MAY+E+ N+IHR+L NILVG
Sbjct: 98 IADAMAYMEKENFIHRNLGDRNILVG 21
>21433
Length = 590
Score = 35.8 bits (81), Expect = 0.044, Method: Compositional matrix adjust.
Identities = 25/89 (28%), Positives = 40/89 (44%)
Frame = +2
Query: 373 QVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKW 432
Q+++ + Y IHRD++ N+L+G KIADFG + + T G + +
Sbjct: 191 QLSSALEYCHYRKVIHRDIKPENLLLGLKGDLKIADFGWSVHAPSSRRTTMCGT---LDY 361
Query: 433 TAPEAALYGRFTIKSDVWSFGILLTELVT 461
PE D+WS G+L E +
Sbjct: 362 LPPEMVEGKTHDENVDLWSLGVLCYEFLV 448
>18881
Length = 762
Score = 35.4 bits (80), Expect = 0.060, Method: Compositional matrix adjust.
Identities = 22/67 (32%), Positives = 35/67 (52%), Gaps = 2/67 (2%)
Frame = -3
Query: 169 PRGTFLIRESETTKGAYSLSIRDWDDMK--GDHVKHYKIRKLDNGGYYITTRAQFETLQQ 226
P GTFLIR + T S R+ + V+H K+ + G +Y+ F+++QQ
Sbjct: 748 PDGTFLIRVTNT-------SARESCPQY*YANAVRHIKVNRNPQGRFYLADGHYFDSVQQ 590
Query: 227 LVQHYSE 233
LV+HY +
Sbjct: 589 LVEHYEK 569
Score = 28.5 bits (62), Expect = 6.3, Method: Compositional matrix adjust.
Identities = 14/45 (31%), Positives = 22/45 (48%), Gaps = 2/45 (4%)
Frame = -3
Query: 101 LSFHKGEKFQIL--NSSEGDWWEARSLTTGETGYIPSNYVAPVDS 143
++ ++ IL N + WW+ +L T + GY P YV DS
Sbjct: 436 VTLKLNDRISILSKNGQDKGWWKGENLRTKKVGYFPLAYVDEEDS 302
>01392
Length = 1806
Score = 35.4 bits (80), Expect = 0.061, Method: Compositional matrix adjust.
Identities = 32/109 (29%), Positives = 51/109 (46%), Gaps = 12/109 (11%)
Frame = -1
Query: 373 QVAAGMAYIERMNYIHRDLRSANIL---VGNGLICKIADFGLARLIE-DNEYTARQGAKF 428
+A + ++ HRDL+ NIL + + + KI DF LA I D + T
Sbjct: 1767 HIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGISCDGDGTKTPELLT 1588
Query: 429 PI---KWTAPEA--ALYG---RFTIKSDVWSFGILLTELVTKGRVPYPG 469
P+ ++ APE A G + + D+WS GI+L ++ G P+ G
Sbjct: 1587 PVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILYIMLC-GYPPFYG 1444
>00394
Length = 548
Score = 35.4 bits (80), Expect = 0.063, Method: Compositional matrix adjust.
Identities = 28/96 (29%), Positives = 47/96 (48%), Gaps = 11/96 (11%)
Frame = -2
Query: 271 LQLIKRLGNGQFGEVWMGTWNGNTKVAI-----KTLKPGTMSPESFLEEAQIMKKLKHDK 325
L+ K +G G F V+ G + VA+ + K + F EEA+++K+L+H
Sbjct: 292 LKFDKEIGRGSFKTVYKGL-DTELGVAVAWCELQDKKWNKAERQRFKEEAEMLKELQHPN 116
Query: 326 LVQLYAVVSE------EPIYIVTEYMNKGSLLDFLK 355
+V+ + E + I +VTE M G+L +LK
Sbjct: 115 IVRFFDYWEEHNHRNRKVIILVTELMTSGTLKTYLK 8
>07933
Length = 728
Score = 35.0 bits (79), Expect = 0.070, Method: Compositional matrix adjust.
Identities = 13/30 (43%), Positives = 18/30 (60%)
Frame = +3
Query: 488 PQDCPISLHELMIHCWKKDPEERPTFEYLQ 517
P CP L+ +M+ CW +P RPTF L+
Sbjct: 3 PNYCPNLLYNIMMQCWSAEPSARPTFHKLE 92
>13664
Length = 507
Score = 35.0 bits (79), Expect = 0.078, Method: Compositional matrix adjust.
Identities = 16/45 (35%), Positives = 25/45 (55%)
Frame = +2
Query: 88 VALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGY 132
VALYDY+A+ D+L+ G+ +L+ WW L G+ G+
Sbjct: 374 VALYDYKAQRSDELTILSGDVIMLLHKDSESWWMGE-LLDGQQGF 505
>36481
Length = 806
Score = 35.0 bits (79), Expect = 0.082, Method: Compositional matrix adjust.
Identities = 37/150 (24%), Positives = 64/150 (42%), Gaps = 13/150 (8%)
Frame = +2
Query: 261 KDVWEIPR-----ESLQLIKRLGNGQFGEVWM--GTWNGNTKVAIKTLKPGTMSPESFLE 313
KD+W R ++L G G FG+V G+ +A+K +K E+
Sbjct: 323 KDIWCTMRGTSSTNDMKLCPHWGEGTFGKVVQCKDLLKGD-DIALKIIKNVDKYREAAKL 499
Query: 314 EAQIMKKLK----HDK--LVQLYAVVSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNL 367
E +++KL+ H K VQ+ ++ +M S+ DFLKD A + +
Sbjct: 500 EINVLEKLREKDPHAKHMCVQMLDWFDYHGHVCISFHMLGLSVFDFLKDNSYGAYPIEQV 679
Query: 368 VDMAAQVAAGMAYIERMNYIHRDLRSANIL 397
++ Q+ + ++ H DL+ NIL
Sbjct: 680 RHISYQLCYAVNFLHENQLTHTDLKPENIL 769
>02638
Length = 1490
Score = 33.9 bits (76), Expect = 0.15, Method: Compositional matrix adjust.
Identities = 25/103 (24%), Positives = 49/103 (47%), Gaps = 7/103 (6%)
Frame = +1
Query: 430 IKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRM---- 485
I + APE + DVWS G ++ E+ T R P+ N+ ++ + +++
Sbjct: 28 IAFMAPEVLRGESYGRACDVWSVGCVMIEMCT-CRPPW---NSHDISNHLALIFKIASSV 195
Query: 486 ---PCPQDCPISLHELMIHCWKKDPEERPTFEYLQSFLEDYFT 525
P P++ + +LM+ C ++D + RP+ + L + FT
Sbjct: 196 DPPPIPENMSPPVRDLMLRCLEQDSDFRPSAKDL--LMHPLFT 318
>31789
Length = 676
Score = 33.9 bits (76), Expect = 0.17, Method: Compositional matrix adjust.
Identities = 30/113 (26%), Positives = 53/113 (46%), Gaps = 11/113 (9%)
Frame = +2
Query: 277 LGNGQFGEVWMGTWNGNTKVAI-----KTLKPGTMSPESFLEEAQIMKKLKHDKLVQLYA 331
+G G F V+ G + VA+ + K + F EEA+++K+L+H +V+ +
Sbjct: 344 IGRGSFKTVYKGL-DTELGVAVAWCELQDKKWNKTERQRFKEEAEMLKELQHPNIVRFFD 520
Query: 332 VVSE------EPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGM 378
E + I +VTE M G+L +LK + + L L + Q+ G+
Sbjct: 521 YWEEHNHRNRKVIILVTELMTSGTLKTYLK--RFKKINLKVLKNWCRQILKGL 673
>37260
Length = 401
Score = 33.9 bits (76), Expect = 0.17, Method: Composition-based stats.
Identities = 17/56 (30%), Positives = 30/56 (53%)
Frame = -1
Query: 149 WYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDWDDMKGDHVKHYK 204
WY+G L ++AE +L+ G+FL+R+S SLS + + ++H+K
Sbjct: 182 WYWGPLSYEEAESKLMD--KRDGSFLVRDSSNENYILSLSFKSMGHVHHTRIEHHK 21
>29360
Length = 363
Score = 33.9 bits (76), Expect = 0.19, Method: Composition-based stats.
Identities = 28/116 (24%), Positives = 50/116 (43%), Gaps = 7/116 (6%)
Frame = +3
Query: 290 WNGNTK--VAIKTLKPGTMSPESFLEEAQIMKKLKHD-----KLVQLYAVVSEEPIYIVT 342
W T VAIK LK E I+++L + V+ + + +
Sbjct: 12 WKKGTSEIVAIKILKNHPSYARQGQIEVSILQRLSQESADDYNFVRAFECFQHKNHTCLV 191
Query: 343 EYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILV 398
M + +L DFLK + + L L + + QV + ++++ IH DL+ NI++
Sbjct: 192 FEMLEQNLYDFLKQNKFQPLPLKYIRPITQQVLTALRKLKQLGLIHADLKPENIML 359
>32359
Length = 928
Score = 31.6 bits (70), Expect = 0.76, Method: Compositional matrix adjust.
Identities = 21/57 (36%), Positives = 32/57 (56%), Gaps = 2/57 (3%)
Frame = -1
Query: 275 KRLGNGQFGEVWMGTWNGNTK-VAIKTLKPGTMSPESFL-EEAQIMKKLKHDKLVQL 329
K +GNG FG V+ ++ VAIK + + + F E QIM+KL+H +V+L
Sbjct: 412 KVIGNGSFGVVYQAKLVDTSELVAIKKV----LQDKRFKNRELQIMRKLEHQNIVKL 254
>32357
Length = 625
Score = 31.6 bits (70), Expect = 0.86, Method: Compositional matrix adjust.
Identities = 14/43 (32%), Positives = 26/43 (60%), Gaps = 1/43 (2%)
Frame = -2
Query: 272 QLIKRLGNGQFGEVWMGTWN-GNTKVAIKTLKPGTMSPESFLE 313
+L+K++G+G FGE+++G N +VA+K P+ + E
Sbjct: 429 RLMKKIGSGSFGEIYLGVHNTSGEEVAVKLELKNAKHPQLYYE 301
>17516
Length = 453
Score = 31.6 bits (70), Expect = 0.90, Method: Compositional matrix adjust.
Identities = 28/101 (27%), Positives = 47/101 (46%), Gaps = 6/101 (5%)
Frame = -3
Query: 434 APEAALY-GRFTIKSDVWSFGILLTELVTKGRVPYPGMNNR---EVLEQVERGYRMPCPQ 489
APE L G++ +K+DV+S I+L EL G+ +++ + + V+ G R
Sbjct: 415 APEVLLQKGQYDMKADVYSLAIILWEL-WYGQDAADHISSHLFGRLEDAVQAGLRPSVTM 239
Query: 490 DC--PISLHELMIHCWKKDPEERPTFEYLQSFLEDYFTATE 528
C P +L+ W+ +RPT F ED+ T+
Sbjct: 238 TCKPPDDWLKLLQSGWEFHASKRPTSRDAAEFFEDFLERTK 116
>18401
Length = 463
Score = 31.2 bits (69), Expect = 1.2, Method: Compositional matrix adjust.
Identities = 18/50 (36%), Positives = 27/50 (54%)
Frame = -3
Query: 432 WTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVER 481
+ APE L ++ DVWS G ++ EL T G + +N+E L +ER
Sbjct: 434 YRAPEVILELGWSHPCDVWSVGCIMFELYT-GYTLFQTHDNKEHLAMMER 288
>13641
Length = 2081
Score = 30.8 bits (68), Expect = 1.3, Method: Compositional matrix adjust.
Identities = 15/58 (25%), Positives = 28/58 (48%), Gaps = 9/58 (15%)
Frame = +2
Query: 89 ALYDYEARTEDD-------LSFHKGEKFQILNSSEGDWWEA--RSLTTGETGYIPSNY 137
A++ + ++ +D+ LSF +G+ I+N + WW+A G IPS +
Sbjct: 164 AMFSFNSKLDDNIPCKEAGLSFQQGDILHIVNQEDAIWWQAYKHGDAKKRAGLIPSRH 337
>23319
Length = 2235
Score = 30.8 bits (68), Expect = 1.3, Method: Compositional matrix adjust.
Identities = 12/45 (26%), Positives = 24/45 (53%)
Frame = +3
Query: 435 PEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQV 479
P+ ++ D+WS G + EL GR +PG ++ + L+++
Sbjct: 3 PDVYXAKMYSTSIDMWSAGCIFAELANAGRPLFPGNDDDDQLKRI 137
>27287
Length = 514
Score = 30.8 bits (68), Expect = 1.5, Method: Compositional matrix adjust.
Identities = 11/30 (36%), Positives = 19/30 (63%)
Frame = -2
Query: 498 LMIHCWKKDPEERPTFEYLQSFLEDYFTAT 527
+M CW++DP +RP+F L L+ T++
Sbjct: 474 IMHSCWQEDPNDRPSFSRLVQELDKMLTSS 385
>29590
Length = 320
Score = 30.4 bits (67), Expect = 2.1, Method: Composition-based stats.
Identities = 13/43 (30%), Positives = 26/43 (60%)
Frame = +3
Query: 432 WTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNRE 474
+ APE Y +I++D+WS G+L ++T P+ G+ +++
Sbjct: 72 YVAPEVLDYEPLSIQTDMWSLGVLSYVMLTACS-PFVGITSKK 197
>27562
Length = 399
Score = 29.3 bits (64), Expect = 3.9, Method: Composition-based stats.
Identities = 18/54 (33%), Positives = 26/54 (48%), Gaps = 3/54 (5%)
Frame = -1
Query: 473 REVLEQVERGYRMPCPQDCPISLHELMIH-CWKKDPEERPT--FEYLQSFLEDY 523
R + Q+ R P+ C SL E++ WKKDP ER E L F++ +
Sbjct: 222 RVLWTQMRRRGTQIQPRPCSSSLFEIL*ETAWKKDPSERTENDIEILMDFMQHF 61
>18663
Length = 600
Score = 28.5 bits (62), Expect = 6.6, Method: Compositional matrix adjust.
Identities = 21/88 (23%), Positives = 36/88 (40%), Gaps = 8/88 (9%)
Frame = +2
Query: 431 KWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPY--------PGMNNREVLEQVERG 482
+ APE + D W+ G+LL E++ GR P+ P N + L QV
Sbjct: 23 NYIAPEILRGEDYGFSVDWWALGVLLYEMLA-GRSPFDIAGASENPDQNTEDYLFQVILE 199
Query: 483 YRMPCPQDCPISLHELMIHCWKKDPEER 510
+ P+ + ++ K+P +R
Sbjct: 200 KTIRIPRSLSVKAASVLKGFLNKNPADR 283
>15741
Length = 402
Score = 28.5 bits (62), Expect = 8.0, Method: Composition-based stats.
Identities = 11/32 (34%), Positives = 18/32 (56%)
Frame = -3
Query: 366 NLVDMAAQVAAGMAYIERMNYIHRDLRSANIL 397
+ A VA GMA++ +HRD+ + N+L
Sbjct: 97 DFFSFALHVARGMAHVANNKIVHRDVAARNVL 2
>32465
Length = 508
Score = 28.1 bits (61), Expect = 9.0, Method: Composition-based stats.
Identities = 18/71 (25%), Positives = 32/71 (45%), Gaps = 2/71 (2%)
Frame = +3
Query: 178 SETTKGAYSLSIRDWDDMKGDHVKHYKIRKLDNGGYYITTRAQFE--TLQQLVQHYSERA 235
SE + + S++ + + D V Y + Y T +++FE T Q V HY +
Sbjct: 207 SENER*SKKCSVQTTGNQQXDQVCFYLFCTITL*AYLSTEKSRFEXFTFSQTVHHYDIQL 386
Query: 236 AGLCCRLVVPC 246
+ LC + + C
Sbjct: 387 SKLCAKSKILC 419
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000313164 | hsapiens_gene_ensembl | Dynamin-2 (EC
3.6.5.5). [Source:Uniprot/SWISSPROT;Acc:P50570]
(866 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
29522 316 2e-86
38072 96 3e-38
13952 35 0.16
08367 33 0.36
14762 32 0.94
15376 32 1.3
>29522
Length = 698
Score = 316 bits (810), Expect = 2e-86, Method: Compositional matrix adjust.
Identities = 144/206 (69%), Positives = 178/206 (86%)
Frame = -3
Query: 344 IEGSGDQVDTLELSGGARINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLF 403
IEG G QV T +LSGGA+INRIFHERFPFELVKMEFDE++LR+EI I+NIHG+RTGLF
Sbjct: 696 IEGFGAQVSTEDLSGGAKINRIFHERFPFELVKMEFDERELRKEIGITIRNIHGIRTGLF 517
Query: 404 TPDMAFEAIVKKQIVKLKEPSLKCVDLVVSELATVIKKCAEKLSSYPRLREETERIVTTY 463
TPDMAFE+IV KQI +LKEPSL CVDLV++EL+ V++K EK+S YPRLREETERIV +
Sbjct: 516 TPDMAFESIVVKQIERLKEPSLHCVDLVITELSQVVRKAGEKMSRYPRLREETERIVNSR 337
Query: 464 IREREGRTKDQILLLIDIEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQVIRRGWLT 523
IRE+E R K+QIL LID + +Y+NTNHEDFIGF+NAQQ++ + KR + NQVIR+GWL+
Sbjct: 336 IREQEQRAKEQILTLIDFQLAYMNTNHEDFIGFSNAQQKAESQSSKRKMGNQVIRKGWLS 157
Query: 524 INNISLMKGGSKEYWFVLTAESLSWY 549
++NIS +KGGSK++WFVLTAESLSW+
Sbjct: 156 LHNISFIKGGSKDFWFVLTAESLSWF 79
>38072
Length = 513
Score = 96.3 bits (238), Expect(2) = 3e-38, Method: Compositional matrix adjust.
Identities = 48/78 (61%), Positives = 60/78 (76%)
Frame = -3
Query: 607 EDVDSWKASFLRAGVYPEKDQAENEDGAQENTFSMDPQLERQVETIRNLVDSYVAIINKS 666
EDVDSWKASFLRAGVYPE+ E+ + + PQLERQVETIRNLVDSY+ I+NK+
Sbjct: 511 EDVDSWKASFLRAGVYPERSSDESSSSKDDYSSMD-PQLERQVETIRNLVDSYMKIVNKT 335
Query: 667 IRDLMPKTIMHLMINNTK 684
RDL+PKTIMH+++ +
Sbjct: 334 QRDLIPKTIMHIIVKKCE 281
Score = 81.3 bits (199), Expect(2) = 3e-38, Method: Compositional matrix adjust.
Identities = 42/86 (48%), Positives = 56/86 (65%)
Frame = -1
Query: 682 NTKAFIHHELLAYLYSSADQSSLMEESADQAQRRDDMLRMYHALKEALNIIGDIXXXXXX 741
N K+FI +LLA+LYS+ DQS++MEES ++AQRRD++LRMYHA +EAL II DI
Sbjct: 288 NVKSFIGSDLLAHLYSN-DQSAMMEESQEEAQRRDEILRMYHATREALTIISDISTTTVS 112
Query: 742 XXXXXXXDDTWLQSASSHSPTPQRRP 767
D WL+ +S +P R P
Sbjct: 111 TPTPPPVKDDWLEPSSGSTPYNGRPP 34
>13952
Length = 577
Score = 34.7 bits (78), Expect = 0.16, Method: Compositional matrix adjust.
Identities = 30/123 (24%), Positives = 59/123 (47%), Gaps = 18/123 (14%)
Frame = -3
Query: 517 IRRGWLTINNISLMKGGS----KEYWFVLTAESLSWYXXXXXXXXXYMLPLDNLKIRDV- 571
++ GWL + +GG K WF+L L ++ ++PL+N+++R++
Sbjct: 419 VKEGWL------MKQGGRYKNWKRRWFILNDNCLYYFQYTADKEPKGIIPLENIQVRELS 258
Query: 572 EKGFMSNKHVFAIFNTEQRNVYK------DLRQIE-------LACDSQEDVDSWKASFLR 618
EK SN F +++ +V K D + +E ++ S E++D+W +S +R
Sbjct: 257 EKSSRSN--AFELYSVSGSDVIKACKVDSDGKVVEGRHSVYRMSASSAEEMDAWISS-IR 87
Query: 619 AGV 621
G+
Sbjct: 86 YGI 78
>08367
Length = 1403
Score = 33.5 bits (75), Expect = 0.36, Method: Compositional matrix adjust.
Identities = 18/59 (30%), Positives = 27/59 (45%)
Frame = -1
Query: 402 LFTPDMAFEAIVKKQIVKLKEPSLKCVDLVVSELATVIKKCAEKLSSYPRLREETERIV 460
L TPD + K P+L + +V+ +A + KLSSYP +R T R +
Sbjct: 497 LLTPDQILYTPSSLPFLL*KRPNLSSIGIVIPNVAAIFLTSFSKLSSYPHIRSLTVRFM 321
>14762
Length = 1307
Score = 32.3 bits (72), Expect = 0.94, Method: Composition-based stats.
Identities = 16/36 (44%), Positives = 21/36 (58%)
Frame = +2
Query: 635 QENTFSMDPQLERQVETIRNLVDSYVAIINKSIRDL 670
Q+NT S PQ ERQV R L SY ++++ R L
Sbjct: 1151 QQNTASHAPQQERQVTVQRTLTPSYACKVSRAYRAL 1258
>15376
Length = 712
Score = 31.6 bits (70), Expect = 1.3, Method: Composition-based stats.
Identities = 22/92 (23%), Positives = 45/92 (48%), Gaps = 14/92 (15%)
Frame = +1
Query: 538 WFVLTAESLSWYXXXXXXXXXYMLPLDNLKIRDV-EKGFMSNKHVFAIFNTEQRNVYK-- 594
WF+L L ++ ++PL+N+++R++ EK SN F +++ +V K
Sbjct: 4 WFILNDNCLYYFQYTADKEPKGIIPLENIQVRELSEKSSRSN--AFELYSVSGSDVIKAC 177
Query: 595 ----DLRQIE-------LACDSQEDVDSWKAS 615
D + +E ++ S E++D+W +S
Sbjct: 178 KVDSDGKVVEGRHSVYRMSASSAEEMDAWISS 273
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000373904 | hsapiens_gene_ensembl | Dynamin-2 (EC
3.6.5.5). [Source:Uniprot/SWISSPROT;Acc:P50570]
(712 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
29522 311 7e-85
38072 97 3e-38
14762 36 0.057
13952 35 0.11
08367 34 0.26
15376 31 1.4
>29522
Length = 698
Score = 311 bits (796), Expect = 7e-85, Method: Compositional matrix adjust.
Identities = 144/210 (68%), Positives = 178/210 (84%)
Frame = -3
Query: 186 IEGSGDQVDTLELSGGARINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLF 245
IEG G QV T +LSGGA+INRIFHERFPFELVKMEFDE++LR+EI I+NIHG+RTGLF
Sbjct: 696 IEGFGAQVSTEDLSGGAKINRIFHERFPFELVKMEFDERELRKEIGITIRNIHGIRTGLF 517
Query: 246 TPDMAFEAIVKKQIVKLKEPSLKCVDLVVSELATVIKKCAEKLSSYPRLREETERIVTTY 305
TPDMAFE+IV KQI +LKEPSL CVDLV++EL+ V++K EK+S YPRLREETERIV +
Sbjct: 516 TPDMAFESIVVKQIERLKEPSLHCVDLVITELSQVVRKAGEKMSRYPRLREETERIVNSR 337
Query: 306 IREREGRTKDQILLLIDIEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQGEILVIRR 365
IRE+E R K+QIL LID + +Y+NTNHEDFIGF+NAQQ++ + KR + NQ VIR+
Sbjct: 336 IREQEQRAKEQILTLIDFQLAYMNTNHEDFIGFSNAQQKAESQSSKRKMGNQ----VIRK 169
Query: 366 GWLTINNISLMKGGSKEYWFVLTAESLSWY 395
GWL+++NIS +KGGSK++WFVLTAESLSW+
Sbjct: 168 GWLSLHNISFIKGGSKDFWFVLTAESLSWF 79
>38072
Length = 513
Score = 96.7 bits (239), Expect(2) = 3e-38, Method: Compositional matrix adjust.
Identities = 48/78 (61%), Positives = 60/78 (76%)
Frame = -3
Query: 453 EDVDSWKASFLRAGVYPEKDQAENEDGAQENTFSMDPQLERQVETIRNLVDSYVAIINKS 512
EDVDSWKASFLRAGVYPE+ E+ + + PQLERQVETIRNLVDSY+ I+NK+
Sbjct: 511 EDVDSWKASFLRAGVYPERSSDESSSSKDDYSSMD-PQLERQVETIRNLVDSYMKIVNKT 335
Query: 513 IRDLMPKTIMHLMINNTK 530
RDL+PKTIMH+++ +
Sbjct: 334 QRDLIPKTIMHIIVKKCE 281
Score = 81.6 bits (200), Expect(2) = 3e-38, Method: Compositional matrix adjust.
Identities = 42/86 (48%), Positives = 56/86 (65%)
Frame = -1
Query: 528 NTKAFIHHELLAYLYSSADQSSLMEESADQAQRRDDMLRMYHALKEALNIIGDIXXXXXX 587
N K+FI +LLA+LYS+ DQS++MEES ++AQRRD++LRMYHA +EAL II DI
Sbjct: 288 NVKSFIGSDLLAHLYSN-DQSAMMEESQEEAQRRDEILRMYHATREALTIISDISTTTVS 112
Query: 588 XXXXXXXDDTWLQSASSHSPTPQRRP 613
D WL+ +S +P R P
Sbjct: 111 TPTPPPVKDDWLEPSSGSTPYNGRPP 34
>14762
Length = 1307
Score = 35.8 bits (81), Expect = 0.057, Method: Compositional matrix adjust.
Identities = 16/37 (43%), Positives = 21/37 (56%)
Frame = +2
Query: 481 QENTFSMDPQLERQVETIRNLVDSYVAIINKSIRDLM 517
Q+NT S PQ ERQV R L SY ++++ R L
Sbjct: 1151 QQNTASHAPQQERQVTVQRTLTPSYACKVSRAYRALC 1261
>13952
Length = 577
Score = 35.0 bits (79), Expect = 0.11, Method: Compositional matrix adjust.
Identities = 30/123 (24%), Positives = 59/123 (47%), Gaps = 18/123 (14%)
Frame = -3
Query: 363 IRRGWLTINNISLMKGGS----KEYWFVLTAESLSWYXXXXXXXXXYMLPLDNLKIRDV- 417
++ GWL + +GG K WF+L L ++ ++PL+N+++R++
Sbjct: 419 VKEGWL------MKQGGRYKNWKRRWFILNDNCLYYFQYTADKEPKGIIPLENIQVRELS 258
Query: 418 EKGFMSNKHVFAIFNTEQRNVYK------DLRQIE-------LACDSQEDVDSWKASFLR 464
EK SN F +++ +V K D + +E ++ S E++D+W +S +R
Sbjct: 257 EKSSRSN--AFELYSVSGSDVIKACKVDSDGKVVEGRHSVYRMSASSAEEMDAWISS-IR 87
Query: 465 AGV 467
G+
Sbjct: 86 YGI 78
>08367
Length = 1403
Score = 33.9 bits (76), Expect = 0.26, Method: Compositional matrix adjust.
Identities = 18/57 (31%), Positives = 26/57 (45%)
Frame = -1
Query: 244 LFTPDMAFEAIVKKQIVKLKEPSLKCVDLVVSELATVIKKCAEKLSSYPRLREETER 300
L TPD + K P+L + +V+ +A + KLSSYP +R T R
Sbjct: 497 LLTPDQILYTPSSLPFLL*KRPNLSSIGIVIPNVAAIFLTSFSKLSSYPHIRSLTVR 327
>15376
Length = 712
Score = 31.2 bits (69), Expect = 1.4, Method: Composition-based stats.
Identities = 22/92 (23%), Positives = 45/92 (48%), Gaps = 14/92 (15%)
Frame = +1
Query: 384 WFVLTAESLSWYXXXXXXXXXYMLPLDNLKIRDV-EKGFMSNKHVFAIFNTEQRNVYK-- 440
WF+L L ++ ++PL+N+++R++ EK SN F +++ +V K
Sbjct: 4 WFILNDNCLYYFQYTADKEPKGIIPLENIQVRELSEKSSRSN--AFELYSVSGSDVIKAC 177
Query: 441 ----DLRQIE-------LACDSQEDVDSWKAS 461
D + +E ++ S E++D+W +S
Sbjct: 178 KVDSDGKVVEGRHSVYRMSASSAEEMDAWISS 273
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000373905 | hsapiens_gene_ensembl | Dynamin-2 (EC
3.6.5.5). [Source:Uniprot/SWISSPROT;Acc:P50570]
(870 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
29522 310 1e-84
38072 96 4e-38
13952 35 0.16
08367 33 0.35
14762 32 0.96
15376 32 1.3
>29522
Length = 698
Score = 310 bits (795), Expect = 1e-84, Method: Compositional matrix adjust.
Identities = 144/210 (68%), Positives = 178/210 (84%)
Frame = -3
Query: 344 IEGSGDQVDTLELSGGARINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLF 403
IEG G QV T +LSGGA+INRIFHERFPFELVKMEFDE++LR+EI I+NIHG+RTGLF
Sbjct: 696 IEGFGAQVSTEDLSGGAKINRIFHERFPFELVKMEFDERELRKEIGITIRNIHGIRTGLF 517
Query: 404 TPDMAFEAIVKKQIVKLKEPSLKCVDLVVSELATVIKKCAEKLSSYPRLREETERIVTTY 463
TPDMAFE+IV KQI +LKEPSL CVDLV++EL+ V++K EK+S YPRLREETERIV +
Sbjct: 516 TPDMAFESIVVKQIERLKEPSLHCVDLVITELSQVVRKAGEKMSRYPRLREETERIVNSR 337
Query: 464 IREREGRTKDQILLLIDIEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQPETLVIRR 523
IRE+E R K+QIL LID + +Y+NTNHEDFIGF+NAQQ++ + KR + NQ VIR+
Sbjct: 336 IREQEQRAKEQILTLIDFQLAYMNTNHEDFIGFSNAQQKAESQSSKRKMGNQ----VIRK 169
Query: 524 GWLTINNISLMKGGSKEYWFVLTAESLSWY 553
GWL+++NIS +KGGSK++WFVLTAESLSW+
Sbjct: 168 GWLSLHNISFIKGGSKDFWFVLTAESLSWF 79
>38072
Length = 513
Score = 96.3 bits (238), Expect(2) = 4e-38, Method: Compositional matrix adjust.
Identities = 48/78 (61%), Positives = 60/78 (76%)
Frame = -3
Query: 611 EDVDSWKASFLRAGVYPEKDQAENEDGAQENTFSMDPQLERQVETIRNLVDSYVAIINKS 670
EDVDSWKASFLRAGVYPE+ E+ + + PQLERQVETIRNLVDSY+ I+NK+
Sbjct: 511 EDVDSWKASFLRAGVYPERSSDESSSSKDDYSSMD-PQLERQVETIRNLVDSYMKIVNKT 335
Query: 671 IRDLMPKTIMHLMINNTK 688
RDL+PKTIMH+++ +
Sbjct: 334 QRDLIPKTIMHIIVKKCE 281
Score = 81.3 bits (199), Expect(2) = 4e-38, Method: Compositional matrix adjust.
Identities = 42/86 (48%), Positives = 56/86 (65%)
Frame = -1
Query: 686 NTKAFIHHELLAYLYSSADQSSLMEESADQAQRRDDMLRMYHALKEALNIIGDIXXXXXX 745
N K+FI +LLA+LYS+ DQS++MEES ++AQRRD++LRMYHA +EAL II DI
Sbjct: 288 NVKSFIGSDLLAHLYSN-DQSAMMEESQEEAQRRDEILRMYHATREALTIISDISTTTVS 112
Query: 746 XXXXXXXDDTWLQSASSHSPTPQRRP 771
D WL+ +S +P R P
Sbjct: 111 TPTPPPVKDDWLEPSSGSTPYNGRPP 34
>13952
Length = 577
Score = 34.7 bits (78), Expect = 0.16, Method: Compositional matrix adjust.
Identities = 30/123 (24%), Positives = 59/123 (47%), Gaps = 18/123 (14%)
Frame = -3
Query: 521 IRRGWLTINNISLMKGGS----KEYWFVLTAESLSWYXXXXXXXXXYMLPLDNLKIRDV- 575
++ GWL + +GG K WF+L L ++ ++PL+N+++R++
Sbjct: 419 VKEGWL------MKQGGRYKNWKRRWFILNDNCLYYFQYTADKEPKGIIPLENIQVRELS 258
Query: 576 EKGFMSNKHVFAIFNTEQRNVYK------DLRQIE-------LACDSQEDVDSWKASFLR 622
EK SN F +++ +V K D + +E ++ S E++D+W +S +R
Sbjct: 257 EKSSRSN--AFELYSVSGSDVIKACKVDSDGKVVEGRHSVYRMSASSAEEMDAWISS-IR 87
Query: 623 AGV 625
G+
Sbjct: 86 YGI 78
>08367
Length = 1403
Score = 33.5 bits (75), Expect = 0.35, Method: Compositional matrix adjust.
Identities = 18/59 (30%), Positives = 27/59 (45%)
Frame = -1
Query: 402 LFTPDMAFEAIVKKQIVKLKEPSLKCVDLVVSELATVIKKCAEKLSSYPRLREETERIV 460
L TPD + K P+L + +V+ +A + KLSSYP +R T R +
Sbjct: 497 LLTPDQILYTPSSLPFLL*KRPNLSSIGIVIPNVAAIFLTSFSKLSSYPHIRSLTVRFM 321
>14762
Length = 1307
Score = 32.0 bits (71), Expect = 0.96, Method: Composition-based stats.
Identities = 16/36 (44%), Positives = 21/36 (58%)
Frame = +2
Query: 639 QENTFSMDPQLERQVETIRNLVDSYVAIINKSIRDL 674
Q+NT S PQ ERQV R L SY ++++ R L
Sbjct: 1151 QQNTASHAPQQERQVTVQRTLTPSYACKVSRAYRAL 1258
>15376
Length = 712
Score = 31.6 bits (70), Expect = 1.3, Method: Composition-based stats.
Identities = 22/92 (23%), Positives = 45/92 (48%), Gaps = 14/92 (15%)
Frame = +1
Query: 542 WFVLTAESLSWYXXXXXXXXXYMLPLDNLKIRDV-EKGFMSNKHVFAIFNTEQRNVYK-- 598
WF+L L ++ ++PL+N+++R++ EK SN F +++ +V K
Sbjct: 4 WFILNDNCLYYFQYTADKEPKGIIPLENIQVRELSEKSSRSN--AFELYSVSGSDVIKAC 177
Query: 599 ----DLRQIE-------LACDSQEDVDSWKAS 619
D + +E ++ S E++D+W +S
Sbjct: 178 KVDSDGKVVEGRHSVYRMSASSAEEMDAWISS 273
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000367902 | hsapiens_gene_ensembl | PITSLRE
serine/threonine-protein kinase CDC2L2 (EC 2.7.11.22)
(Galactosyltransferase-associated protein kinase p58/GTA) (Cell
division cycle 2-like protein kinase 2) (CDK11).
[Source:Uniprot/SWISSPROT;Acc:Q9UQ88]
(770 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
29581 292 3e-84
01060 229 4e-60
01756 222 4e-58
14126 219 3e-57
04591 195 7e-50
32000 170 2e-42
01707 162 4e-40
04138 151 1e-36
01966 119 3e-28
23319 103 4e-22
00300 96 8e-20
03294 87 2e-17
18921 86 7e-17
06405 83 4e-16
13592 82 6e-16
12721 82 8e-16
01718 80 4e-15
09606 78 2e-14
03508 77 3e-14
20559 66 1e-13
12453 74 2e-13
14420 74 3e-13
15910 71 1e-12
26560 68 1e-11
19761 65 7e-11
18484 65 9e-11
21578 64 2e-10
27546 63 5e-10
14116 62 1e-09
13212 62 1e-09
30755 62 1e-09
03240 61 1e-09
13066 61 1e-09
28638 61 2e-09
26909 60 3e-09
19094 59 7e-09
21808 58 1e-08
24241 57 3e-08
11185 57 3e-08
27405 56 6e-08
19301 56 6e-08
18287 56 6e-08
28157 56 7e-08
26711 55 1e-07
07940 55 1e-07
31489 55 1e-07
12672 54 3e-07
17253 54 3e-07
04852 52 6e-07
00715 52 9e-07
18401 52 1e-06
21079 51 2e-06
00392 50 2e-06
16003 50 3e-06
12786 50 3e-06
17300 49 6e-06
31885 47 2e-05
11780 45 7e-05
05084 45 1e-04
20640 44 2e-04
07836 44 3e-04
17975 44 3e-04
21433 42 0.001
07291 42 0.001
15549 40 0.005
02638 40 0.005
14477 39 0.006
26009 32 0.007
18481 39 0.007
37602 39 0.007
16708 39 0.007
13078 38 0.018
00486 35 0.093
36481 33 0.30
15931 30 2.7
00145 30 2.8
20152 30 4.2
38560 29 6.4
>29581
Length = 1278
Score = 292 bits (747), Expect(2) = 3e-84, Method: Compositional matrix adjust.
Identities = 133/261 (50%), Positives = 183/261 (70%)
Frame = -2
Query: 464 ILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLR 523
+L +H NIV ++E+VVG ++D +++VM Y E DL SL++ M PF +VK +++QLL+
Sbjct: 1193 LLNLRHQNIVQLQEVVVGKSLDSLFLVMEYCEQDLASLLDNMPAPFSESQVKCIVLQLLK 1014
Query: 524 GVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPEL 583
G+++LH+ +I+HRDLK SNLL++ G +K+ DFGLAR YG P K TP VVT WYRAPEL
Sbjct: 1013 GLRYLHEAFIIHRDLKVSNLLMTDKGCVKIADFGLARNYGKPQKPMTPKVVTLWYRAPEL 834
Query: 584 LLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSEL 643
L G+K +STA+DMWS GCI GELL KPL PG S++ QI + + LGTP++ IWPG+S+L
Sbjct: 833 LFGSKTHSTAIDMWSAGCILGELLGHKPLMPGRSDLQQIELIMELLGTPNDTIWPGFSQL 654
Query: 644 PVVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPL 703
P ++ T + PYNNLR F LS+ G L+N Y P +R +AED L+H YF+E P
Sbjct: 653 PAFEQFTLKKQPYNNLRHTF-PWLSESGIRLLNGLFMYHPQKRATAEDCLEHSYFKEQPY 477
Query: 704 PIDPSMFPTWPAKSEQQRVKR 724
P DP P++P Q R+KR
Sbjct: 476 PCDPEFMPSFP----QHRLKR 426
Score = 38.9 bits (89), Expect(2) = 3e-84, Method: Composition-based stats.
Identities = 17/35 (48%), Positives = 25/35 (71%)
Frame = -1
Query: 436 DEIVALKRLKMEKEKEGFPITSLREINTILKAQHP 470
+EIVALK+++M E+ G PI+ LREIN ++ P
Sbjct: 1278 NEIVALKKMRMTGERYGIPISGLREINIFAQSATP 1174
>01060
Length = 1800
Score = 229 bits (583), Expect = 4e-60, Method: Compositional matrix adjust.
Identities = 122/338 (36%), Positives = 204/338 (60%), Gaps = 2/338 (0%)
Frame = +1
Query: 388 LLPIELKQELPKYLPALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKME 447
LL + +K+ + + AL + +FQ +I EGTYGVVY+ + + T +A+K++++
Sbjct: 22 LLKLNIKRLMMDFETALS---DLTDFQ---KIGEGTYGVVYKCRHRATGRKLAMKKIRLR 183
Query: 448 KEKEGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQ 507
++G P +++REI + + +H NIV + ++++ +++++V ++ DLK ++ +
Sbjct: 184 GSEDGVPSSAIREIAMLRELRHTNIVCLEDVIMED--ERLFLVFEFLSMDLKMYIDKFPE 357
Query: 508 PFLPGE--VKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSP 565
+ VK+ + Q++ G+ H I+HRDLK NLL++H G +K+ DFG+AR + P
Sbjct: 358 GVVLDRRLVKSYVFQIVTGIXFCHQRRIVHRDLKPQNLLINHTGAIKIADFGMARTFALP 537
Query: 566 LKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKV 625
++AYT VVT WYRAPE+L+GA +YST VD+WS+G IF ++L + P+F G+SEIDQ+ K+
Sbjct: 538 VRAYTHEVVTLWYRAPEILMGASKYSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKI 717
Query: 626 FKELGTPSEKIWPGYSELPVVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGR 685
F+ +GTP+E+ WP + +LP M F L + L S G DL+ + L P +
Sbjct: 718 FRIIGTPTEQTWPEFHKLPAFNGM-FPLWKEGKLSETLTDLDS-LGLDLIERTLKCDPAQ 891
Query: 686 RISAEDGLKHEYFRETPLPIDPSMFPTWPAKSEQQRVK 723
RIS + L+H YF + P P+ P S R+K
Sbjct: 892 RISCKKMLQHAYFLNVDTSVKPVDVPS-PEHS*STRLK 1002
>01756
Length = 1858
Score = 222 bits (566), Expect = 4e-58, Method: Compositional matrix adjust.
Identities = 117/309 (37%), Positives = 187/309 (60%), Gaps = 10/309 (3%)
Frame = -3
Query: 407 CRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILK 466
C +++ L +I +GT+G V++A+ KKT ++VA+K++ M+ EKEGFPIT+LREI +
Sbjct: 1754 CDEDAKYEKLAKIGQGTFGEVFKARCKKTKQVVAMKKVLMDNEKEGFPITALREIKILQL 1575
Query: 467 AQHPNIVTVREIV----VGSNMDK--IYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQ 520
H N+V + EI +N K Y+V + EHDL L+ M F E+K +M Q
Sbjct: 1574 LNHENVVDLIEICSTKATSANRYKSMFYLVFEFCEHDLAGLLSNMSVVFNLPEIKEVMKQ 1395
Query: 521 LLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKA---YTPVVVTQW 577
L+ G+ ++H N ILHRD+K +N+L++ G+LK+ DFGLAR + L+ YT VVT W
Sbjct: 1394 LMNGLYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLW 1215
Query: 578 YRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIW 637
YR PELLLG + YSTA+D W GCI E+ T+ P+ G +E +Q+ + + G+ + ++W
Sbjct: 1214 YRPPELLLGDRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQNQLTLITQLCGSITPEVW 1035
Query: 638 PGYSELPVVKKMTFSEHPYNNLRKRFGALLSDQ-GFDLMNKFLTYFPGRRISAEDGLKHE 696
PG L + + + +++R + D DL++K L PG+R+++++ L H+
Sbjct: 1034 PGVERLELYNSLDLPQGNKRKVKERLRYYIKDAYALDLLDKLLALDPGKRVNSDEALSHD 855
Query: 697 YFRETPLPI 705
+F P P+
Sbjct: 854 FFWMDPEPL 828
>14126
Length = 1265
Score = 219 bits (559), Expect = 3e-57, Method: Compositional matrix adjust.
Identities = 125/299 (41%), Positives = 182/299 (60%), Gaps = 9/299 (3%)
Frame = +3
Query: 411 EEFQCLNRIEEGTYGVVYRAKD-KKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQ- 468
++++ + I G YG VY+A+D + E VA+KR+++ +EG P+ ++REI+ + + +
Sbjct: 189 QKYEEVAVIGNGAYGTVYKARDLRNQGEFVAMKRIRLNNTEEGMPMMAIREISMLKQLEQ 368
Query: 469 --HPNIVTVREIVVGSNMDK---IYIVMNYVEHDLKSLMETMKQPFL-PGEVKTLMIQLL 522
HPN+V + ++ + D+ + +V Y+EHDL + + P L P +K LM+QLL
Sbjct: 369 YEHPNVVRLLDVSHNTITDREIRLNLVFEYIEHDLATYLAKCPSPGLGPDRIKDLMLQLL 548
Query: 523 RGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPE 582
GV LH N I+HRDLK NLL+S G LK+ DFGLAR Y + A T VVVT WYR+PE
Sbjct: 549 NGVDFLHSNRIVHRDLKPQNLLISKDGRLKLADFGLARIYSFHM-ALTTVVVTLWYRSPE 725
Query: 583 LLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWP-GYS 641
+L+ A EY T+VD+WS GCIF EL T++ LF G+SE DQ+ K+F+ +G P WP G S
Sbjct: 726 VLMQA-EYGTSVDIWSCGCIFAELFTRRALFKGSSEFDQLKKIFEVIGLPPAGDWPEGVS 902
Query: 642 ELPVVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 700
V + +F P L+ + Q DLM K L + GRRIS+ + L H Y R+
Sbjct: 903 ----VHRNSFRPTPPVPLQTLVPE-MDPQAKDLMEKMLVFKSGRRISSRESLLHPYLRD 1064
>04591
Length = 1117
Score = 195 bits (495), Expect = 7e-50, Method: Compositional matrix adjust.
Identities = 102/267 (38%), Positives = 161/267 (60%), Gaps = 7/267 (2%)
Frame = -2
Query: 450 KEGFPITSLREINTILKAQHPNIVTVREIV------VGSNMDKIYIVMNYVEHDLKSLME 503
KEGFPIT+LREI + + +H N+V ++EI Y++ Y ++DL L+
Sbjct: 1101 KEGFPITALREIKILQQLEHENVVQLQEICHTQAGPYNRYKSTFYLIFEYCDYDLAGLLN 922
Query: 504 TMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYG 563
++ F + K LM QLL G+ ++H ILHRD+K +N+LL+ G+LK+ DFGL+R +
Sbjct: 921 NLRVKFSLADKKNLMSQLLNGLFYIHTKQILHRDIKAANILLTRDGVLKLADFGLSRPWV 742
Query: 564 SPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQIN 623
K T VVT WYR PELLLG +EY +DMW VGCI E+ ++KPL G SE Q++
Sbjct: 741 KS-KRLTNRVVTLWYRPPELLLGEREYGPEIDMWGVGCIMAEMWSRKPLMQGRSEQHQLS 565
Query: 624 KVFKELGTPSEKIWPGYSELPVVKKMTFSEHPYNNLRKRFGALLSD-QGFDLMNKFLTYF 682
+ G+ + ++WPG ++L + K+ + +++R LL + +G +L++ FL
Sbjct: 564 LITDLCGSLNAEVWPGVTKLELYGKLDLPQGKPRKVKERMLDLLKNKEGAELIDIFLRLD 385
Query: 683 PGRRISAEDGLKHEYFRETPLPIDPSM 709
PG+R++ ++ L H++F PLP PS+
Sbjct: 384 PGQRMNCDNALSHDFFWVDPLP-SPSL 307
>32000
Length = 644
Score = 170 bits (430), Expect = 2e-42, Method: Compositional matrix adjust.
Identities = 79/150 (52%), Positives = 106/150 (70%)
Frame = -1
Query: 551 LKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQK 610
+K+ DFGLAR +G P++ YT V+T WYRAPE+LLG + YS VD+WS+GCIF E++T++
Sbjct: 572 MKIADFGLARVFGLPVRTYTHEVITLWYRAPEILLGCRFYSVPVDIWSLGCIFVEMMTRR 393
Query: 611 PLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKMTFSEHPYNNLRKRFGALLSDQ 670
LFPG+SEIDQ+ ++F+ LGTP EK+WPG S+LP K TF + P NL LS
Sbjct: 392 ALFPGDSEIDQLYRIFRTLGTPDEKVWPGVSKLPDYKP-TFPKWPLKNLETVVS--LSKV 222
Query: 671 GFDLMNKFLTYFPGRRISAEDGLKHEYFRE 700
G DL+ + LTY P RRISA ++H YF +
Sbjct: 221 GLDLLKRMLTYNPNRRISARSAMRHPYFND 132
>01707
Length = 757
Score = 162 bits (411), Expect = 4e-40, Method: Compositional matrix adjust.
Identities = 81/221 (36%), Positives = 138/221 (62%)
Frame = +1
Query: 410 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 469
+E+++ + +I EG+YGVV++ ++K+T ++VA+K+ ++ ++REI + + +H
Sbjct: 61 MEKYEKIGKIGEGSYGVVFKCRNKETSQLVAIKKFVESEDDPLIKKIAMREIRMLKQLKH 240
Query: 470 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLH 529
PN+V R I V ++++V +YV+H L + ++ + VK ++ Q L V H
Sbjct: 241 PNLV--RLIEVFRRKKRLHLVFDYVDHTLLNELDRYPRGLPEPMVKRIIYQTLLAVNFCH 414
Query: 530 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKE 589
+HRD+K N+L++ G +K+ DFG AR P YT V T+WYRAPELL+G +
Sbjct: 415 QYNTIHRDVKPENILITRQGQVKLCDFGFARILTGPGDEYTDYVATRWYRAPELLVGDTQ 594
Query: 590 YSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELG 630
Y VD+W++GC+F ELLT + L+PG S++DQ++ + K LG
Sbjct: 595 YGPPVDVWAIGCVFAELLTGQALWPGRSDVDQLHLIRKTLG 717
>04138
Length = 800
Score = 151 bits (381), Expect = 1e-36, Method: Compositional matrix adjust.
Identities = 72/178 (40%), Positives = 111/178 (62%), Gaps = 6/178 (3%)
Frame = +1
Query: 527 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKA---YTPVVVTQWYRAPEL 583
++H N ILHRD+K +N+L++ G+LK+ DFGLAR + L+ YT VVT WYR PEL
Sbjct: 58 YIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRPPEL 237
Query: 584 LLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSEL 643
LLG + YSTA+D W GCI E+ T+ P+ G +E +Q+ + + G+ + ++WPG ++L
Sbjct: 238 LLGDRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQNQLTLITQLCGSITPEVWPGVTQL 417
Query: 644 PVVKKM--TFSEHPYNNLRKRFGALLSD-QGFDLMNKFLTYFPGRRISAEDGLKHEYF 698
+ ++ + N +R RF +L D G DL + L P +RISA++ L H++F
Sbjct: 418 SMYHQIKGALAAGRKNIIRDRFARILKDPYGLDLFERLLKMDPSQRISADEALNHDFF 591
>01966
Length = 1735
Score = 119 bits (297), Expect(2) = 3e-28, Method: Compositional matrix adjust.
Identities = 55/175 (31%), Positives = 107/175 (61%), Gaps = 2/175 (1%)
Frame = -1
Query: 430 AKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYI 489
+ + T +A+K++++ ++G P +++REI + + +H NIV + ++++ +++++
Sbjct: 1654 CRHRATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTNIVCLEDVIMED--ERLFL 1481
Query: 490 VMNYVEHDLKSLMETMKQPFLPGE--VKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSH 547
V ++ DLK ++ + + VK+ + Q++ G+ H I+HRDLK NLL++H
Sbjct: 1480 VFEFLSMDLKMYIDKFPEGVVLDRRLVKSYVFQIVTGINFCHQRRIVHRDLKPQNLLINH 1301
Query: 548 AGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCI 602
G +K+ DFG+AR + P++AYT VVT WYRAPE+L+G + + W+ G +
Sbjct: 1300 TGAIKIADFGMARTFALPVRAYTHEVVTLWYRAPEILMGPQ---STPPXWTCGAL 1145
Score = 25.4 bits (54), Expect(2) = 3e-28, Method: Composition-based stats.
Identities = 10/13 (76%), Positives = 12/13 (92%)
Frame = -2
Query: 416 LNRIEEGTYGVVY 428
L++I EGTYGVVY
Sbjct: 1695 LSKIGEGTYGVVY 1657
Score = 97.8 bits (242), Expect = 2e-20, Method: Compositional matrix adjust.
Identities = 54/138 (39%), Positives = 80/138 (57%)
Frame = -3
Query: 586 GAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPV 645
GA +YST VD+WS+G IF ++L + P+F G+SEIDQ+ K+F+ +GTP+E+ WP + +LP
Sbjct: 1187 GASKYSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKLPA 1008
Query: 646 VKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPI 705
M F L + L S G DL+ + L P +RIS + L+H YF +
Sbjct: 1007 FNGM-FPLWKEGKLSETLTDLDS-LGLDLIERTLKCDPAQRISCKKMLQHAYFLNVDTSV 834
Query: 706 DPSMFPTWPAKSEQQRVK 723
P P+ P +S R+K
Sbjct: 833 KPVDVPS-PEQS*STRLK 783
>23319
Length = 2235
Score = 103 bits (256), Expect = 4e-22, Method: Compositional matrix adjust.
Identities = 50/117 (42%), Positives = 72/117 (61%), Gaps = 1/117 (0%)
Frame = +3
Query: 587 AKEYSTAVDMWSVGCIFGELLTQ-KPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPV 645
AK YST++DMWS GCIF EL +PLFPGN + DQ+ ++FK LGTP+E WPG ++LP
Sbjct: 18 AKMYSTSIDMWSAGCIFAELANAGRPLFPGNDDDDQLKRIFKLLGTPTEDQWPGMTQLPN 197
Query: 646 VKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETP 702
+ F + ++ L+ +G DL+ L P R+SA++ L+H YF + P
Sbjct: 198 YR--MFPMYHVTTTWQQVVPKLNSKGRDLLQCLLVCCPSDRMSADEALQHPYFADLP 362
>00300
Length = 2318
Score = 95.5 bits (236), Expect = 8e-20, Method: Compositional matrix adjust.
Identities = 66/207 (31%), Positives = 108/207 (52%), Gaps = 13/207 (6%)
Frame = -1
Query: 417 NRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKA----QHPNI 472
N+I EG +G VY A + T E++ALK +K + + LRE+ +K QH N+
Sbjct: 1640 NKIGEGQFGKVYTAVNMSTGELMALKEMKFQPND----LQQLREMCDEIKIFEGIQHENL 1473
Query: 473 VTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNW 532
V + V + D++ + M Y D ++ E K ++ +++ V HLH+N
Sbjct: 1472 VKYYGVEV--HKDEMLMFMEYC--DTGTIEEAAKMGLPEYLIRRYTREIVLAVNHLHENS 1305
Query: 533 ILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTP-------VVVTQWYRAPELLL 585
I+HRD+K +N+ L+ G +K+GDFG + + LK++T +V T Y APE+
Sbjct: 1304 IVHRDIKGANIFLTSNGHVKLGDFGCSVK----LKSHTTMPGEFHNLVGTTAYMAPEVFT 1137
Query: 586 GAKE--YSTAVDMWSVGCIFGELLTQK 610
+ Y A D+WS+GC+ E+ T K
Sbjct: 1136 QNDQGGYGRAADIWSLGCVVIEMATGK 1056
>03294
Length = 1684
Score = 87.4 bits (215), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 49/130 (37%), Positives = 73/130 (56%)
Frame = -1
Query: 594 VDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKMTFSE 653
VD+WS+G IF ++L + P+F G+SEIDQ+ K+F+ +GTP+E+ WP + +LP M F
Sbjct: 1672 VDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKLPAFNGM-FPL 1496
Query: 654 HPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSMFPTW 713
L + L S G DL+ + L P +RIS + L+H YF + P P+
Sbjct: 1495 WKEGKLSETLTDLDS-LGLDLIERTLKCDPAQRISCKKMLQHAYFLNVDTSVKPVDVPS- 1322
Query: 714 PAKSEQQRVK 723
P S R+K
Sbjct: 1321 PEHS*STRLK 1292
>18921
Length = 697
Score = 85.5 bits (210), Expect = 7e-17, Method: Compositional matrix adjust.
Identities = 57/205 (27%), Positives = 109/205 (53%), Gaps = 6/205 (2%)
Frame = +2
Query: 413 FQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNI 472
F L ++ EG+YG V+++ K+T +++A+K++ ++ + + ++EI+ + + I
Sbjct: 35 FDILGKLGEGSYGSVFKSLHKETGQVLAIKQVPVDTDLQEI----IKEISIMQQCDSKYI 202
Query: 473 VTVREIVVGS---NMDKIYIVMNYV-EHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHL 528
V GS N D ++IVM Y + +M + + E+ T++ L+G+ +L
Sbjct: 203 VKYY----GSYFKNTD-LWIVMEYCGAGSVSDIMRLRNKTLVEREIATILYYTLKGLXYL 367
Query: 529 HDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELL--LG 586
H +HRD+K N+LL++ G K+ DFG+A + + V+ T ++ APE++ +G
Sbjct: 368 HSRRKIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTPYWMAPEVIQEIG 547
Query: 587 AKEYSTAVDMWSVGCIFGELLTQKP 611
Y D+WS+G E+ KP
Sbjct: 548 ---YDCVADIWSLGITALEMAEGKP 613
>06405
Length = 1965
Score = 83.2 bits (204), Expect = 4e-16, Method: Compositional matrix adjust.
Identities = 63/205 (30%), Positives = 102/205 (49%), Gaps = 8/205 (3%)
Frame = +1
Query: 412 EFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILK-AQHP 470
E +R+ G YG VY A K+ ++IVA+K LK ++ + E I+K +HP
Sbjct: 262 EIAMKHRLGGGQYGDVYEAMWKRYNKIVAVKTLK----EDTMALNDFLEEAAIMKEMKHP 429
Query: 471 NIVTVREIVVGSNMDKIYIVMNYVEHD--LKSLMETMKQPFLPGEVKTLMIQLLRGVKHL 528
N+V + + V + YIV ++ H L L + ++ P + + Q+ G+ +L
Sbjct: 430 NLVQL--LGVCTREPPFYIVTEFMPHGNLLDYLRSSTREENGPTALMYMATQIASGMAYL 603
Query: 529 HDNWILHRDLKTSNLLLSHAGILKVGDFGLAR-----EYGSPLKAYTPVVVTQWYRAPEL 583
+HRDL N L++ + ++KV DFGLAR Y + + A P+ +W APE
Sbjct: 604 ETKNFIHRDLAARNCLVADSNMVKVADFGLARLMKDDTYTAHIGAKFPI---KW-TAPE- 768
Query: 584 LLGAKEYSTAVDMWSVGCIFGELLT 608
L +ST D+W+ G + EL T
Sbjct: 769 GLAFNRFSTRSDIWAFGVLLWELAT 843
>13592
Length = 980
Score = 82.4 bits (202), Expect = 6e-16, Method: Compositional matrix adjust.
Identities = 80/295 (27%), Positives = 138/295 (46%), Gaps = 13/295 (4%)
Frame = +2
Query: 418 RIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVRE 477
+I +G +G VY A + T E++A+K + ++ + E+ + +H N+V
Sbjct: 5 KIGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETRALKNVAEELKILEGIKHKNLVRYYG 184
Query: 478 IVVGSNMDKIYIVMNYV-EHDLKSLMETMKQPFLPGEV-KTLMIQLLRGVKHLHDNWILH 535
I V + +++ I M E L+SL+E LP + + QLL GV LH + I+H
Sbjct: 185 IEV--HREELLIFMELCSEGTLESLVELTGG--LPEALSRRFTAQLLSGVAELHKHGIVH 352
Query: 536 RDLKTSNL-LLSHAGILKVGDFGLAREYGSPLKAYTPV-------VVTQWYRAPELL--L 585
RD+KT+N+ L+ + LK+GDFG A + ++A+T V V TQ Y APE+
Sbjct: 353 RDIKTANIFLVDGSNSLKLGDFGSAVK----IQAHTTVPGELQGYVGTQAYMAPEVFTKT 520
Query: 586 GAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGY-SELP 644
+ + D+WSVGC+ E+ + K + W + S
Sbjct: 521 NSDGHGRLADIWSVGCVVVEMASGK------------------------RPWAQFDSNFQ 628
Query: 645 VVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFR 699
++ K+ E P + LS +G D ++ L + P +R+SA + L+ + +
Sbjct: 629 IMFKVGMGEKP------QAPESLSQEGHDFIDHCLQHDPKQRLSAIELLEQNFCK 775
>12721
Length = 821
Score = 82.0 bits (201), Expect = 8e-16, Method: Compositional matrix adjust.
Identities = 53/196 (27%), Positives = 106/196 (54%)
Frame = +1
Query: 418 RIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVRE 477
+I EG+ G+V A + ++ A+K++ + K++ + E+ + HPNIV +
Sbjct: 109 KIGEGSTGIVCIATSRDGRQM-AVKKMDLRKQQRRELL--FNEVVVMRDYHHPNIVEMYN 279
Query: 478 IVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRD 537
+ + D++++VM ++E + + T + ++ T+ L+ + LH N ++HRD
Sbjct: 280 SYLVN--DELWVVMEFMEGGALTDIVTNNR-MDEVQIATVCRACLKALAFLHANGVIHRD 450
Query: 538 LKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMW 597
+K+ ++LLSH G +K+ DFG + L+ +V T ++ APE ++ Y VD+W
Sbjct: 451 IKSDSILLSHDGKVKLXDFGFCAQVTQDLQKRKSLVGTPYWMAPE-VISRLPYGPEVDIW 627
Query: 598 SVGCIFGELLTQKPLF 613
S+G + E++ +P F
Sbjct: 628 SLGIMVMEMIDAEPPF 675
>01718
Length = 959
Score = 79.7 bits (195), Expect = 4e-15, Method: Compositional matrix adjust.
Identities = 60/218 (27%), Positives = 107/218 (49%), Gaps = 6/218 (2%)
Frame = +3
Query: 403 ALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREIN 462
A+ +++F C +I G + V++ + T +++ALK M + LRE+
Sbjct: 126 AVSALTRLDDFIC-EKIGAGFFSEVFKVTHRITGQVMALKMNTMTSNRHNM----LREVQ 290
Query: 463 TILKAQHPNIVTVREIVVGSNMDKIYIVMNYV-EHDLKSLMETMKQPFLPGEVKTLMIQL 521
+ + QH NI+ + V +++ + Y+ +L+ L+E + + L + L
Sbjct: 291 LLNRLQHANILRFMGVCVHEG--QLHALTEYIPSGNLEQLLEKKDEELPWTQRIQLTLGL 464
Query: 522 LRGVKHLHDNWILHRDLKTSNLLL----SHAGILKVGDFGLAREYGSPL-KAYTPVVVTQ 576
RG+ +LH +HRDL + N+L+ +H + DFGLA + PL K P V +
Sbjct: 465 ARGLDYLHSTRFIHRDLTSKNILIRREDNHGYHAVIADFGLATKIPDPLDKEKLPTVGSP 644
Query: 577 WYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFP 614
++ APE+L G Y+ D++SVG I E+ + P P
Sbjct: 645 YWMAPEVLNG-HFYNERADLFSVGIIMCEITARIPADP 755
>09606
Length = 1300
Score = 77.8 bits (190), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 82/314 (26%), Positives = 134/314 (42%), Gaps = 24/314 (7%)
Frame = -3
Query: 410 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 469
+E F + +G + ++Y+ + K T VA+ + EK K ++R + I H
Sbjct: 1118 MENFVLYEELGKGEHSIIYKGRRKGTINFVAIHCI--EKCKRPEVTNTVRMTHDI---SH 954
Query: 470 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPF-LP-GEVKTLMIQLLRGVKH 527
PN+V E SN +++V+ SL + + Q LP ++ I L+ G+ +
Sbjct: 953 PNVVQFHEWYETSN--HLWLVVELCTGG--SLADILAQDHHLPETSIRDFGIHLVTGLHY 786
Query: 528 LHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAY------------------ 569
+H IL DL+ S +LL +G+LK DFGL++ G L+
Sbjct: 785 IHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQWNIQSAEE 606
Query: 570 ----TPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKV 625
P + Y APE+ GA E S D+W++GC+F E+ + P F G + +KV
Sbjct: 605 MMKQVPTSGSPTYMAPEVFQGA-EPSIMSDLWALGCVFYEMFSGHPPFLGETYDITKDKV 429
Query: 626 FKELGTPSEKIWPGYSELPVVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGR 685
K +P LP VK S P S + +L+ L R
Sbjct: 428 LN-------KEFP----LPKVKGSRLSAKP------------SPEFLNLLESLLQKDSTR 318
Query: 686 RISAEDGLKHEYFR 699
R+S +KH +++
Sbjct: 317 RLSWASLVKHAFWQ 276
>03508
Length = 1463
Score = 76.6 bits (187), Expect = 3e-14, Method: Compositional matrix adjust.
Identities = 39/122 (31%), Positives = 72/122 (59%), Gaps = 2/122 (1%)
Frame = +1
Query: 495 EHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGI-LKV 553
EH + + + Q F +++ + +L++ + H I+HRD+K N+++ H L++
Sbjct: 820 EHVNNTDFKQLYQTFTDYDIRFYLYELMKALDFCHSMGIMHRDVKPHNVMIDHENKKLRL 999
Query: 554 GDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQK-PL 612
D+GLA E+ P Y V +++++ PELLL + Y ++DMWS+GC+F ++ +K PL
Sbjct: 1000IDWGLA-EFYHPGMEYNVRVASRYFKGPELLLDYQMYDYSLDMWSLGCMFASMIFRKEPL 1176
Query: 613 FP 614
P
Sbjct: 1177LP 1182
Score = 35.0 bits (79), Expect = 0.10, Method: Compositional matrix adjust.
Identities = 27/114 (23%), Positives = 51/114 (44%), Gaps = 12/114 (10%)
Frame = +2
Query: 597 WSVG----CIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKMTFS 652
W+ G C+ + P F G+ DQ+ ++ K LGT + ++ + + F+
Sbjct: 1118 WTCGVWAACLPA*SSGKSPFFHGHDNYDQLVRIAKVLGT--DDLYGYIEKYQIDLDPRFN 1291
Query: 653 EHPYNNLRKRF--------GALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYF 698
+ + RKR+ L+S + D ++K L Y R++A + + H YF
Sbjct: 1292 DILGRHSRKRWERFVHSENQHLISPEALDFLDKLLRYDHNERLTAREAMDHPYF 1453
>20559
Length = 430
Score = 65.9 bits (159), Expect(2) = 1e-13, Method: Compositional matrix adjust.
Identities = 31/82 (37%), Positives = 58/82 (70%)
Frame = -2
Query: 398 PKYLPALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITS 457
P +L + +++++ L +I EGTYG V++AK+++T EIVALKR++++ + EG P ++
Sbjct: 414 PTHLHSF*LKHKMQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSA 235
Query: 458 LREINTILKAQHPNIVTVREIV 479
LREI + + +H NIV + +++
Sbjct: 234 LREICLLKELKHRNIVRLHDVL 169
Score = 29.3 bits (64), Expect(2) = 1e-13, Method: Composition-based stats.
Identities = 14/36 (38%), Positives = 19/36 (52%)
Frame = -3
Query: 493 YVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHL 528
Y + DLK +T P VK+ + QLLRG+ L
Sbjct: 134 YCDQDLKKYFDTCNGEIDPDTVKSFLHQLLRGLGFL 27
>12453
Length = 680
Score = 74.3 bits (181), Expect = 2e-13, Method: Composition-based stats.
Identities = 41/100 (41%), Positives = 55/100 (55%)
Frame = +3
Query: 599 VGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKMTFSEHPYNN 658
VGCIF E+ +PLFPG++ D+++ +FK LGTP+E P S P + +
Sbjct: 6 VGCIFYEMACGRPLFPGSTVEDELHLIFKTLGTPTEDSLPSISRNPDFLALNLPHYQGEA 185
Query: 659 LRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYF 698
L L SD G DL+ KFL Y R+SA D LKH +F
Sbjct: 186 LITIAPRLDSD-GLDLLAKFLKYNAKIRVSAADSLKHSFF 302
>14420
Length = 528
Score = 73.6 bits (179), Expect = 3e-13, Method: Compositional matrix adjust.
Identities = 44/156 (28%), Positives = 90/156 (57%), Gaps = 2/156 (1%)
Frame = +2
Query: 458 LREINTILKAQHPNIVT-VREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLP-GEVK 515
+ EI + + Q+PNIV + +VG +++++VM ++ SL + + + + G++
Sbjct: 44 INEILVMRENQNPNIVNYLDSYLVG---EELWVVMEFLAGG--SLTDVVTETCMDEGQIA 208
Query: 516 TLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVT 575
+ + L+ ++ LH+N ++HRD+K+ N+LL G +K+ DFG + + +V T
Sbjct: 209 AVCRECLQALEFLHENQVIHRDIKSDNILLGMDGSVKLTDFGFCAQLSPEQSKRSTMVGT 388
Query: 576 QWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKP 611
++ APE ++ K+Y VD+WS+G + E++ +P
Sbjct: 389 PYWMAPE-VVTRKQYGPTVDIWSLGVMCIEMIEGEP 493
>15910
Length = 1361
Score = 71.2 bits (173), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 49/125 (39%), Positives = 67/125 (53%), Gaps = 3/125 (2%)
Frame = +2
Query: 521 LLRGVKHLHDNWILHRDLKTSNLL---LSHAGILKVGDFGLAREYGSPLKAYTPVVVTQW 577
+L GV+++H N ++HRDLK NLL ++ LK+ DFGL+R P + V T
Sbjct: 491 ILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLADFGLSRII-EPEVQMSTVCGTPG 667
Query: 578 YRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIW 637
Y APE+L G K Y+ +VDMWSVG I LL F +E + K+ K E+ W
Sbjct: 668 YCAPEVLKGDK-YTPSVDMWSVGVIAYILLCGYEPFFAENEFEMYRKIIKGEYKFDEEYW 844
Query: 638 PGYSE 642
SE
Sbjct: 845 SEISE 859
>26560
Length = 398
Score = 68.2 bits (165), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 37/119 (31%), Positives = 66/119 (55%), Gaps = 4/119 (3%)
Frame = -1
Query: 509 FLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKA 568
F EV+ +++ G++H+H ++++RDLK +N+LL G +++ D GLA ++ K
Sbjct: 365 FTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGLACDFSK--KR 192
Query: 569 YTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLF----PGNSEIDQIN 623
V T Y APE+L+ + Y ++ D +S GC+ +LL F G + ID++
Sbjct: 191 PHASVGTHGYMAPEVLMKGQSYDSSADWFSFGCMLYKLLKGHSPFRQHNQGQARIDRMT 15
>19761
Length = 473
Score = 65.5 bits (158), Expect = 7e-11, Method: Compositional matrix adjust.
Identities = 36/104 (34%), Positives = 60/104 (57%)
Frame = -3
Query: 527 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLG 586
H H ILHRDLK N+ ++ G +++GD GLAR+ P T V T Y +PE +L
Sbjct: 372 HTHTPVILHRDLKPQNIYVTEKGDVRLGDLGLARKLTGPADFATSQVGTIMYLSPE-ILS 196
Query: 587 AKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELG 630
+ Y++ D+WS+GC+F ++ +K G+ E+ + + + +G
Sbjct: 195 QQPYNSKSDIWSLGCVFYDITGKK----GSDEMGVMFLLVQVMG 76
>18484
Length = 635
Score = 65.5 bits (158), Expect = 9e-11, Method: Compositional matrix adjust.
Identities = 35/99 (35%), Positives = 55/99 (55%)
Frame = +1
Query: 520 QLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYR 579
++ G+ LHD I++RDLK N++L G +K+ DFG+ +E + T Y
Sbjct: 67 EIAVGLFFLHDQGIIYRDLKLDNVMLDSEGHIKIADFGMCKEGMTGDATTRTFCGTPDYI 246
Query: 580 APELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSE 618
APE++L + YS +VD W+ G + E+L +P F G E
Sbjct: 247 APEIVL-YQPYSKSVDWWAYGVLLFEMLAGQPPFDGEDE 360
>21578
Length = 524
Score = 64.3 bits (155), Expect = 2e-10, Method: Composition-based stats.
Identities = 26/33 (78%), Positives = 31/33 (93%)
Frame = +2
Query: 393 LKQELPKYLPALQGCRSVEEFQCLNRIEEGTYG 425
LK++LP YLPA+QGCR+VEEF C+NRIEEGTYG
Sbjct: 425 LKEDLPVYLPAIQGCRNVEEFHCMNRIEEGTYG 523
>27546
Length = 426
Score = 62.8 bits (151), Expect = 5e-10, Method: Composition-based stats.
Identities = 38/113 (33%), Positives = 60/113 (53%), Gaps = 2/113 (1%)
Frame = -1
Query: 450 KEGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQ-- 507
K+ FP RE+ + + HPNI+ + I+ KI+I M Y E ++ +K+
Sbjct: 348 KKFFP----RELEILTRLDHPNIIQIHSIL--QRGPKIFIFMRYAEKG--DMLSHIKKTG 193
Query: 508 PFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAR 560
P + K Q+ + +++LH + I HRDLK N+LLS +K+ DFG AR
Sbjct: 192 PIDEAQTKVWFFQMAKALQYLHSHDIAHRDLKCENILLSKRLNVKIADFGFAR 34
>14116
Length = 1017
Score = 61.6 bits (148), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 61/205 (29%), Positives = 99/205 (48%), Gaps = 14/205 (6%)
Frame = -1
Query: 419 IEEGTYGVVYRA----KDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVT 474
I +G +G V R ++K D +VA+K L +E + L+E + H N++T
Sbjct: 612 IGKGNFGCVKRGFLTLPEQKGDILVAVKTLHNNNPREIELQSFLQEALIMKDFHHSNVLT 433
Query: 475 VREIVVGSNMDKI-YIVMNYVEHD--LKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDN 531
+ I + N+D + +V+ +++H L + + QP + ++ + + RG+ +L
Sbjct: 432 LIGICL--NLDDMPLVVLPFMKHGDLLTYIRDDQHQPTIK-DLIMYGVDIARGMDYLAGL 262
Query: 532 WILHRDLKTSNLLLSHAGILKVGDFGLAR-----EYGSP--LKAYTPVVVTQWYRAPELL 584
+HRDL N +L +KV DFGLAR EY S KA PV +W L
Sbjct: 261 KFVHRDLAARNCMLDEDFHVKVADFGLARDIYEKEYYSSENKKAKLPV---KWMALESLE 91
Query: 585 LGAKEYSTAVDMWSVGCIFGELLTQ 609
G Y + D+WS G + ELLT+
Sbjct: 90 KG--NYDSKTDVWSYGVVLWELLTR 22
>13212
Length = 1067
Score = 61.6 bits (148), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 46/206 (22%), Positives = 93/206 (45%), Gaps = 4/206 (1%)
Frame = -1
Query: 498 LKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFG 557
L S+M +++P ++ + ++ + LH + ++HRD+K N+LL+ G +K+ DFG
Sbjct: 1022 LDSIMVDLEKPMTEAQICYVCHEMCMALDFLHRHHVIHRDIKAGNVLLTIDGEVKLADFG 843
Query: 558 LAREYGSPLKAYTPVVVTQWYRAPELLLGA----KEYSTAVDMWSVGCIFGELLTQKPLF 613
++ + + + T ++ APE++L Y D+WS+G E
Sbjct: 842 VSAKNTQTQQKRDTFIGTPYWMAPEVVLCETLKDTPYDFKADIWSLGVTLIE-------- 687
Query: 614 PGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKMTFSEHPYNNLRKRFGALLSDQGFD 673
F ++ P++++ P + V+ K+ S+ P K++ L D
Sbjct: 686 ------------FAQIEPPNKEMHP----MRVLIKIHKSDPPTLEKPKKWTKLFK----D 567
Query: 674 LMNKFLTYFPGRRISAEDGLKHEYFR 699
+ K L P R +A + L+H + +
Sbjct: 566 FIAKCLVKDPNLRPTAAELLEHPFMK 489
>30755
Length = 1137
Score = 61.6 bits (148), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 35/94 (37%), Positives = 51/94 (54%), Gaps = 3/94 (3%)
Frame = +2
Query: 520 QLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLARE---YGSPLKAYTPVVVTQ 576
+++ + +LH I++RDLK NLLL G +KV DFGL +E YG K + T
Sbjct: 56 EIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCKEDITYGRTTKTFCG---TP 226
Query: 577 WYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQK 610
Y APE +L +Y AVD W G + E++ +
Sbjct: 227 EYLAPE-VLDDNDYGRAVDWWGTGVVMYEMICGR 325
>03240
Length = 1683
Score = 61.2 bits (147), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 62/262 (23%), Positives = 105/262 (40%), Gaps = 48/262 (18%)
Frame = -3
Query: 413 FQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNI 472
F+ + + G +G V + T + A+K L+ + + ++ IL A+ N
Sbjct: 1285 FEKIKTLGVGAFGEVSLCRKNDTGMLYAMKTLRKSDVLKRNQVAHVKAERDIL-AEADNE 1109
Query: 473 VTVREIVVGSNMDKIYIVMNYVEH-DLKSL---METMKQPFLPGEVKTLMIQLLRGVKHL 528
V+ + + +Y VM+YV DL L ME + +P + + +L++ ++ +
Sbjct: 1108 WVVKLYYSFQDHNYLYFVMDYVPGGDLMGLLIRMEILDEPL----ARFYVAELVQAIESV 941
Query: 529 HDNWILHRDLKTSNLLLSHAGILKVGDFGL-------------------AREYGSPLKAY 569
H +HRD+K N+L+ G +K+ DFGL AR+ +K
Sbjct: 940 HRMGFIHRDIKPDNILIDRNGHIKLTDFGLCTGFRWTHNSKYYQRDGTHARQDSMEVKCQ 761
Query: 570 T-------------------------PVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFG 604
+V T Y APE+L Y++ D WSVG I
Sbjct: 760 LDEQCQCEILKPLERRRKREQRCLAHSLVGTPNYIAPEVLSRLGGYTSVCDWWSVGVILF 581
Query: 605 ELLTQKPLFPGNSEIDQINKVF 626
E+L P F N+ + KV
Sbjct: 580 EMLVGHPPFYANTPAETQYKVI 515
>13066
Length = 551
Score = 61.2 bits (147), Expect = 1e-09, Method: Composition-based stats.
Identities = 52/185 (28%), Positives = 87/185 (47%), Gaps = 6/185 (3%)
Frame = +3
Query: 422 GTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREIVVG 481
GT+ Y K +I+ ++ ++ ++ FP RE++ + K HP I+ + I+
Sbjct: 24 GTFNDGYGRNIKLACKIIDKEKAPVDFVEKFFP----RELDLLTKLDHPYIIQIHSIL-- 185
Query: 482 SNMDKIYIVMNYVEH-DLKSLMETMKQPFLP-GEVKTLMIQLLRGVKHLHDNWILHRDLK 539
K +I M + E DL + ++ + F+ + K Q+ + +LH + HRDLK
Sbjct: 186 QRXPKNFIFMRFAERGDLLTYIQEVG--FVKEKQAKIWFYQMTTALNYLHSYDVAHRDLK 359
Query: 540 TSNLLLSHAGILKVGDFGLA----REYGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVD 595
N+LLS +K+ DFG A E G + T + Y APE++ GA D
Sbjct: 360 CENILLSSHFNVKLADFGFACACITESGEKYMSRT-YCGSAAYAAPEIVYGAPYAPKVAD 536
Query: 596 MWSVG 600
WS+G
Sbjct: 537 AWSLG 551
>28638
Length = 1458
Score = 60.8 bits (146), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 33/81 (40%), Positives = 51/81 (62%), Gaps = 2/81 (2%)
Frame = -1
Query: 533 ILHRDLKTSNLLLSHA--GILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEY 590
I+H DLK N+LL + +K+ DFG + + G + Y + +++YR+PE+LLG Y
Sbjct: 768 IIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQY---IQSRFYRSPEVLLGVP-Y 601
Query: 591 STAVDMWSVGCIFGELLTQKP 611
A+DMWS+GCI E+ T +P
Sbjct: 600 DLAIDMWSLGCILVEMHTGEP 538
Score = 29.6 bits (65), Expect = 4.3, Method: Compositional matrix adjust.
Identities = 15/52 (28%), Positives = 22/52 (42%), Gaps = 5/52 (9%)
Frame = -2
Query: 590 YSTAVDMWSVGC-----IFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKI 636
Y W + C + PLF G++E DQ+ K+ + LG P I
Sbjct: 617 YXXCPMTWPLTCGXWAVYWWRCTXGNPLFAGSNEFDQMMKIVEVLGVPPRHI 462
>26909
Length = 394
Score = 60.1 bits (144), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 38/119 (31%), Positives = 57/119 (47%), Gaps = 16/119 (13%)
Frame = +2
Query: 602 IFGELLTQKPLFPGNSEI---------DQINKVFKELGTPSEKIWPGYSELPVVKKMT-- 650
IF ELLT +P+F E DQ++++F +G P EK W +P +++T
Sbjct: 2 IFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFPQEKDWEDIRRMPEHQQLTKD 181
Query: 651 FSEHPYNNLR-----KRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLP 704
F Y N ++ + F L+ K LT P +RI++E +K YF E PLP
Sbjct: 182 FKRSSYVNCNLMKYMEKHKVKADSKAFHLLQKLLTMDPVKRITSEQAMKDPYFLEEPLP 358
>19094
Length = 898
Score = 58.9 bits (141), Expect = 7e-09, Method: Compositional matrix adjust.
Identities = 31/105 (29%), Positives = 58/105 (55%), Gaps = 2/105 (1%)
Frame = +1
Query: 498 LKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFG 557
+ +M + + E+ T++ L+G+ +LH +HRD+K N+LL++ G K+ DFG
Sbjct: 16 VSDIMRLRNKTLVEREIATILYYTLKGL*YLHSRRKIHRDIKAGNILLNNEGHAKLADFG 195
Query: 558 LAREYGSPLKAYTPVVVTQWYRAPELL--LGAKEYSTAVDMWSVG 600
+A + + V+ T ++ APE++ +G Y D+WS+G
Sbjct: 196 VAGQLTDTMAKRNTVIGTPYWMAPEVIQEIG---YDCVADIWSLG 321
>21808
Length = 1011
Score = 58.2 bits (139), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 56/201 (27%), Positives = 96/201 (47%), Gaps = 14/201 (6%)
Frame = +1
Query: 439 VALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDL 498
VA+K LK P L E + K +HP ++ + V + D I+I+ +++
Sbjct: 28 VAIKTLKSGTMD---PKDFLAEAQIMKKLRHPKLIQL--YAVCTQDDPIFIITELMKNG- 189
Query: 499 KSLMETMKQPFLPGEVKTLMI--------QLLRGVKHLHDNWILHRDLKTSNLLLSHAGI 550
SL+E FL G+ + L + Q+ G+ +L +HRDL N+L+S
Sbjct: 190 -SLLE-----FLQGKGRVLKLPALIDIGAQIACGMAYLESQNYIHRDLAARNILVSDNNT 351
Query: 551 LKVGDFGLAR-----EYGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGE 605
+K+ DFGLAR EY + + A P+ +W APE ++ D+WS G + E
Sbjct: 352 VKIADFGLARVIKEDEYEARVGARFPI---KW-TAPE-AANYNRFTIKSDVWSFGILLTE 516
Query: 606 LLTQKPL-FPGNSEIDQINKV 625
+T + +PG + + +++V
Sbjct: 517 TVTYGRVPYPGMTNAEVLHQV 579
>24241
Length = 413
Score = 57.0 bits (136), Expect = 3e-08, Method: Composition-based stats.
Identities = 25/92 (27%), Positives = 57/92 (61%)
Frame = -2
Query: 416 LNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTV 475
L++I EGTYGVVY+ + + T +A+K++++ ++G P +++REI + + +H +
Sbjct: 328 LSKIGEGTYGVVYKCRHRATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTQXLVC 149
Query: 476 REIVVGSNMDKIYIVMNYVEHDLKSLMETMKQ 507
E V+ + +++++V ++ DLK ++ +
Sbjct: 148 LEDVIMED-ERLFLVFEFLSMDLKMYIDKFPE 56
>11185
Length = 473
Score = 57.0 bits (136), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 35/117 (29%), Positives = 56/117 (47%), Gaps = 22/117 (18%)
Frame = +1
Query: 514 VKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAY---- 569
++ I L+ G+ ++H IL DL+ S +LL +G+LK DFGL++ G L+
Sbjct: 7 IRDFGIHLVTGLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKF 186
Query: 570 ------------------TPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLT 608
P + Y APE+ GA E S D+W++GC+F E+ +
Sbjct: 187 AEAGDQWNIQSAEEMMKQVPTSGSPTYMAPEVFQGA-EPSIMSDLWALGCVFYEMFS 354
>27405
Length = 532
Score = 55.8 bits (133), Expect = 6e-08, Method: Compositional matrix adjust.
Identities = 28/87 (32%), Positives = 51/87 (58%)
Frame = -3
Query: 509 FLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKA 568
F EV+ +++ G++H+H ++++RDLK +N+LL G +++ D GLA ++ K
Sbjct: 263 FTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGLACDFSK--KK 90
Query: 569 YTPVVVTQWYRAPELLLGAKEYSTAVD 595
V T Y APE+L+ + Y ++ D
Sbjct: 89 PHASVGTHGYMAPEVLMKGQAYDSSAD 9
>19301
Length = 712
Score = 55.8 bits (133), Expect = 6e-08, Method: Compositional matrix adjust.
Identities = 42/144 (29%), Positives = 74/144 (51%), Gaps = 2/144 (1%)
Frame = +2
Query: 416 LNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTV 475
L + G G V+ K E VA+K+++ KE + I +LR++N HPNI++
Sbjct: 320 LEWLGSGAQGAVFLGK--LCAEEVAVKKVRDIKETD---IRNLRKLN------HPNIISF 466
Query: 476 REIVVGSNMDKIYIVMNYVEHDLKSLMETMK--QPFLPGEVKTLMIQLLRGVKHLHDNWI 533
+ + + I+M Y + L E ++ + P V Q+ G+ +LH + I
Sbjct: 467 KGVC--TQAPCYCIIMEYCPYG--QLYEVLRDGKEIPPALVLDWSKQIASGMNYLHSHKI 634
Query: 534 LHRDLKTSNLLLSHAGILKVGDFG 557
+HRDLK+ N+L++ ++K+ DFG
Sbjct: 635 IHRDLKSPNVLVAKNDVVKISDFG 706
>18287
Length = 678
Score = 55.8 bits (133), Expect = 6e-08, Method: Composition-based stats.
Identities = 35/119 (29%), Positives = 53/119 (44%), Gaps = 8/119 (6%)
Frame = -3
Query: 590 YSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKM 649
Y ++D+WSVGCIF ELL+++ LF + Q++ + +GTP + E
Sbjct: 673 YDYSIDIWSVGCIFAELLSRRILFQAQGPVQQLDMIINLVGTPRPEDMERACE------- 515
Query: 650 TFSEHPYNNLRKRFGALL--------SDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 700
H N +R L + + L+ + L P RISAE+ L H Y E
Sbjct: 514 GARNHILNQPFRRQNLLTLYNLSPHATHEAVRLLTRMLILNPKNRISAEEALSHPYLDE 338
>28157
Length = 400
Score = 55.8 bits (133), Expect = 7e-08, Method: Composition-based stats.
Identities = 44/129 (34%), Positives = 67/129 (51%), Gaps = 8/129 (6%)
Frame = +3
Query: 439 VALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSNMDK-IYIVMNYVEHD 497
VA+KR++ E+EK+ F ++E+ + + HPNIV + G+ D + +VM Y E
Sbjct: 9 VAVKRIESEQEKKSF----MQELKQLSRVSHPNIVCL----YGACRDHPVCLVMEYAEGG 164
Query: 498 --LKSLMETMKQP-FLPGEVKTLMIQLLRGVKHLHD---NWILHRDLKTSNLLLSHAGI- 550
L + QP + ++Q GV++LH ++HRDLK NLLL G
Sbjct: 165 SLYNVLHGSGPQPQYTAAHAMNWLLQCALGVEYLHGMKPKALIHRDLKPPNLLLIQCGTK 344
Query: 551 LKVGDFGLA 559
LK+ DFG A
Sbjct: 345 LKICDFGTA 371
>26711
Length = 405
Score = 55.1 bits (131), Expect = 1e-07, Method: Composition-based stats.
Identities = 39/111 (35%), Positives = 61/111 (54%), Gaps = 6/111 (5%)
Frame = -2
Query: 520 QLLRGVKHLHDNWILHRDLKTSNLLLSHAGI--LKVGDFGLAREYGSPLKAY----TPVV 573
Q+L ++H+H ++H DLK SNLLLS + +++ DFGLAR+ P + + TP
Sbjct: 392 QVLDILQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARKLYPPQETFLNHGTP-- 219
Query: 574 VTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINK 624
+ +PE L K STA D+W VG + LL+ + F +S + + K
Sbjct: 218 ---GFTSPE-ALDVKPISTASDVWGVGVLAYILLSGQSPFQADSATESLKK 78
>07940
Length = 1336
Score = 55.1 bits (131), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 35/112 (31%), Positives = 56/112 (50%), Gaps = 6/112 (5%)
Frame = -3
Query: 503 ETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLARE- 561
+ M + P ++ + Q+ RG+++L +HRDL N+L++ +LK+ DFGL R
Sbjct: 374 QDMLKMLTPKDLISYAYQVARGMEYLASKQCIHRDLAARNVLVAEEYVLKIADFGLTRNL 195
Query: 562 -----YGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLT 608
Y PV +W APE L K Y++ D+WS G + E+ T
Sbjct: 194 QQFDYYRKTTDGRLPV---KW-MAPEALFDRK-YTSKSDVWSYGVLLWEIFT 54
>31489
Length = 329
Score = 55.1 bits (131), Expect = 1e-07, Method: Composition-based stats.
Identities = 28/81 (34%), Positives = 50/81 (61%), Gaps = 4/81 (4%)
Frame = +3
Query: 468 QHPNIVTVREIVVGSN----MDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLR 523
+H NI+++REI+ + I++V + +E DL ++ + QP ++ + Q+LR
Sbjct: 24 KHDNIISIREILKPKDSYHDFKDIHVVFDLMESDLHRIIYS-DQPLTEEHIRYFLYQILR 200
Query: 524 GVKHLHDNWILHRDLKTSNLL 544
G+K++H ++HRDLK SNLL
Sbjct: 201 GLKYIHSANVVHRDLKPSNLL 263
>12672
Length = 773
Score = 53.9 bits (128), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 31/89 (34%), Positives = 50/89 (56%), Gaps = 4/89 (4%)
Frame = +3
Query: 524 GVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREY----GSPLKAYTPVVVTQWYR 579
G+++L+DN +HRD+KT+N+LL KVGDF G ++ + V+ T Y
Sbjct: 27 GIQYLNDNGHVHRDIKTANILLDSEYTAKVGDFATVVSAPSGEGKTVQNASVVIGTAAYL 206
Query: 580 APELLLGAKEYSTAVDMWSVGCIFGELLT 608
APE + + ST +D +S G + E++T
Sbjct: 207 APEAI--HFDVSTKLDSYSFGVVLLEVIT 287
>17253
Length = 483
Score = 53.5 bits (127), Expect = 3e-07, Method: Composition-based stats.
Identities = 44/140 (31%), Positives = 67/140 (47%), Gaps = 14/140 (10%)
Frame = -1
Query: 447 EKEKEGFPITSLREINTILK-AQHPNIVTVREIVVGSNMDKIYIVMNYVEH-DLKSLMET 504
+ EK F LRE++ + K +HPN+V+ S D I+M + H DL S +
Sbjct: 426 DAEKSEF----LRELSIMRKLPRHPNVVSFMGCCTMS--DPALILMEFCCHGDLLSFLRK 265
Query: 505 MKQP----FLPGEVKTLM--------IQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILK 552
++P FL L + + RG+ H+ +N I+HRD+ N+L+S + K
Sbjct: 264 -RRPDRTVFLTSTANDLTARDFFSFALHVARGMAHVANNKIVHRDVAARNVLISERNVCK 88
Query: 553 VGDFGLAREYGSPLKAYTPV 572
V DFGL+R G Y V
Sbjct: 87 VSDFGLSRRVGDQNDVYEIV 28
>04852
Length = 1462
Score = 52.4 bits (124), Expect = 6e-07, Method: Compositional matrix adjust.
Identities = 30/90 (33%), Positives = 48/90 (53%)
Frame = +1
Query: 519 IQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWY 578
Q+ RG++ L +HRDL N+L++ +LK+ DFGL+R K + +W
Sbjct: 346 FQIARGMEFLASRKCIHRDLAARNVLVTEEHVLKIADFGLSRTGDYYKKRSGGRLPVKWM 525
Query: 579 RAPELLLGAKEYSTAVDMWSVGCIFGELLT 608
APE L + Y+T D+WS G + E+ +
Sbjct: 526 -APEALFDMR-YTTKSDVWSFGVVLWEIFS 609
>00715
Length = 1788
Score = 52.0 bits (123), Expect = 9e-07, Method: Compositional matrix adjust.
Identities = 48/177 (27%), Positives = 84/177 (47%), Gaps = 29/177 (16%)
Frame = +1
Query: 468 QHPNIVTVREIVVGSNM-----DKIYIVMNYV-EHDLKSLMETMKQPFLPGEVKTLMIQL 521
+H N+V++ +G+ D ++ M YV +L++++ +Q +L +Q+
Sbjct: 100 RHVNVVSI----LGATSLHRFEDGAWLAMEYVGPLNLQTILNDHQQDIDSSMRLSLALQM 267
Query: 522 LRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREY---------------GSPL 566
RG+ +LH I+H DLK +N LL+ L++ DFG + G+ L
Sbjct: 268 ARGLHYLHSINIVHLDLKPANCLLTRDLKLRIADFGCCHQLTPTGLDMGEREGGMAGNEL 447
Query: 567 KAYTPV--------VVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPG 615
+ TPV T YRAPELL G + S D++S+G ++ T++ + G
Sbjct: 448 E-LTPVQGAWKNELAGTLAYRAPELLKGLQP-SVRSDVYSLGITLWQMCTRQGPYEG 612
>18401
Length = 463
Score = 51.6 bits (122), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 39/144 (27%), Positives = 66/144 (45%), Gaps = 14/144 (9%)
Frame = -3
Query: 569 YTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKE 628
++ +V T+ YRAPE++L +S D+WSVGCI EL T LF + + + + +
Sbjct: 461 HSTIVSTRHYRAPEVILELG-WSHPCDVWSVGCIMFELYTGYTLFQTHDNKEHLAMMERI 285
Query: 629 LGTPSEKI--------WPGYSELPVVKKMTFSEHPYNNLRKRFGALLS------DQGFDL 674
LG+ ++ + + L V ++ + + + N + + Q FDL
Sbjct: 284 LGSLPYRMAKKTKKQKYFHHGRLDVPERSSMARYVRENTKPLLRYVKDRENKDHQQLFDL 105
Query: 675 MNKFLTYFPGRRISAEDGLKHEYF 698
M K L Y R S L+H +F
Sbjct: 104 MKKLLAYEASSRYSLLQALQHPFF 33
>21079
Length = 878
Score = 51.2 bits (121), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 34/91 (37%), Positives = 50/91 (54%), Gaps = 2/91 (2%)
Frame = +1
Query: 520 QLLRGVKHLHDNWILHRDLKTSNLLL--SHAGILKVGDFGLAREYGSPLKAYTPVVVTQW 577
Q+ GV ++H ILH DLK N+L ++ +K+ DFGLAR Y P + + T
Sbjct: 151 QICSGVGYMHTQSILHLDLKPENVLCVSDNSNQIKIIDFGLARFY-KPGDSLQVLFGTPE 327
Query: 578 YRAPELLLGAKEYSTAVDMWSVGCIFGELLT 608
+ APE ++ E + DMWS+G I LL+
Sbjct: 328 FIAPE-VVNYDEINFTTDMWSIGVICYILLS 417
>00392
Length = 668
Score = 50.4 bits (119), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 46/163 (28%), Positives = 74/163 (45%), Gaps = 6/163 (3%)
Frame = +3
Query: 468 QHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTL---MIQLLRG 524
QHPNIV + N +++ E ++T + F VK L Q+L+G
Sbjct: 105 QHPNIVRFFDYWEEHNHRNRKVIILVTELMTSGTLKTYLKRFKKPNVKILKNWCRQVLKG 284
Query: 525 VKHLHDNW--ILHRDLKTSNLLLSH-AGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAP 581
+ LH ++HRDLK N+ ++ G +K+GD GLA V+ T + AP
Sbjct: 285 LYFLHTRTPPVIHRDLKCDNIFITGPTGSVKIGDLGLATLKNQSFAK--SVIGTPEFMAP 458
Query: 582 ELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINK 624
E+ + Y AVD+++ G E+ + + + S QI K
Sbjct: 459 EMY--EEHYDEAVDVYAFGMCMLEMASSEYPYSECSNAAQIYK 581
>16003
Length = 926
Score = 50.4 bits (119), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 35/99 (35%), Positives = 51/99 (51%)
Frame = -1
Query: 606 LLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKMTFSEHPYNNLRKRFGA 665
LL + P PG++++DQ+ K+F LGTP+E WP + LP + F L++ F A
Sbjct: 926 LLIRLPFLPGDTDLDQLGKIFNMLGTPTETEWPAVTSLP--DYIQFKHCQKQPLKEIFTA 753
Query: 666 LLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLP 704
D +L++K L P R +A LK YF P P
Sbjct: 752 -AGDDLLELLDKLLAMNPLHRCTATQALKMPYFSNKPYP 639
>12786
Length = 460
Score = 50.1 bits (118), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 38/117 (32%), Positives = 58/117 (49%), Gaps = 23/117 (19%)
Frame = -3
Query: 520 QLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLA----REYGSPLKAYTPVVVT 575
++LR VK LH+ ++H DLK +N +L AG LK+ DFG+A ++ S LK V T
Sbjct: 386 EMLRAVKALHNEGVIHSDLKPANFMLV-AGNLKLIDFGIANTLQQDKTSVLK--DSRVGT 216
Query: 576 QWYRAPELLLGAKE-----------------YSTAV--DMWSVGCIFGELLTQKPLF 613
Y +PE ++ A + Y V D+WS+GCI ++ + F
Sbjct: 215 PSYMSPEAIMAACDDSADDSMEEDGHRTKPKYKVGVRSDVWSLGCILYNMVYGRTPF 45
>17300
Length = 480
Score = 49.3 bits (116), Expect = 6e-06, Method: Composition-based stats.
Identities = 31/90 (34%), Positives = 51/90 (56%), Gaps = 5/90 (5%)
Frame = +1
Query: 524 GVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLK--AYTP---VVVTQWY 578
G+ L D +HRDL N+L++ + KV DFGL+RE S AYT + +W
Sbjct: 10 GMGXLADMGYVHRDLAARNILVNEILVCKVADFGLSREIESDTTEGAYTTKGGKIPVRW- 186
Query: 579 RAPELLLGAKEYSTAVDMWSVGCIFGELLT 608
APE + +++++A D+WS G + E+++
Sbjct: 187 TAPE-AIAYRKFTSASDVWSFGVVMWEVMS 273
>31885
Length = 529
Score = 47.4 bits (111), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 46/161 (28%), Positives = 73/161 (45%), Gaps = 4/161 (2%)
Frame = -2
Query: 461 INTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQ 520
++ + + HP +V + D +V ++ DL+ M+ + F VK + Q
Sbjct: 519 VDMLTRLDHPFLVNLW-YAFQDEEDLFMVVDLFLGGDLRYHMQQ-EVSFREDCVKFYLCQ 346
Query: 521 LLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRA 580
L + +L I+HRD+K N+LL G V DF +A + A T T+ Y A
Sbjct: 345 LALVLDYLRSQKIVHRDIKPDNILLDEQGHCHVTDFNIATQLEDDELA-TSTSGTRPYMA 169
Query: 581 PELLLGA----KEYSTAVDMWSVGCIFGELLTQKPLFPGNS 617
PE+ A + Y VD WS+G ELL ++ F +S
Sbjct: 168 PEVYGVAINERRGYGFPVDWWSLGVSLFELLKKRRPFSVHS 46
>11780
Length = 1713
Score = 45.4 bits (106), Expect = 7e-05, Method: Compositional matrix adjust.
Identities = 51/202 (25%), Positives = 98/202 (48%), Gaps = 4/202 (1%)
Frame = +3
Query: 419 IEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREI 478
I +G +G VY+ + + VA+K+LK +K+ + L+E + + +H N+V + +
Sbjct: 621 IGKGDFGDVYKGMYR--GQPVAIKQLK---DKDRGEQSFLQEASVMTSLRHDNLVRLIGV 785
Query: 479 VVGSNMDKIYIVMNYV-EHDLKSLMETMKQPFLPGEVK-TLMIQLLRGVKHLHDNWILHR 536
V+G + I++V ++ + +L + + + + + + +++L ++HR
Sbjct: 786 VLG---ETIFLVTEFMGKGNLVEYLRSRGRSVITKKDQINFATDTCAAMEYLESKRLVHR 956
Query: 537 DLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEY--STAV 594
DL N+L+ G KV DFGLA+ +G + T V + APE L K + V
Sbjct: 957 DLAARNVLVHDDGKAKVSDFGLAK-FGDF--SQTSVKFPIKWTAPEALRENKIH*QVRHV 1127
Query: 595 DMWSVGCIFGELLTQKPLFPGN 616
++W + + G LL P N
Sbjct: 1128ELWHI--VMGNLLLWSSALP*N 1187
>05084
Length = 1324
Score = 44.7 bits (104), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 28/92 (30%), Positives = 43/92 (46%), Gaps = 4/92 (4%)
Frame = +2
Query: 613 FPGNSEIDQINKVFKELGTPS----EKIWPGYSELPVVKKMTFSEHPYNNLRKRFGALLS 668
PG+S +DQ+ ++ K LGTP+ ++ P YSE K HP+ K F
Sbjct: 2 LPGDSGVDQLVEIIKVLGTPTREQIREMNPNYSEF---KFPQIKAHPWT---KVFRPRTP 163
Query: 669 DQGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 700
+ L+++ L Y P RI + H +F E
Sbjct: 164 PEAIQLVSRLLEYTPSARIQPMEACAHAFFDE 259
>20640
Length = 1492
Score = 44.3 bits (103), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 26/79 (32%), Positives = 40/79 (50%), Gaps = 4/79 (5%)
Frame = +1
Query: 534 LHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYT----PVVVTQWYRAPELLLGAKE 589
+HRDL T N L+ H ++K+ DFGLAR S + Y + +W +L +
Sbjct: 10 VHRDLATRNCLVGHDLVVKISDFGLARSVHS-VDYYRGSEHDAIPIRWMPLEAILYN--K 180
Query: 590 YSTAVDMWSVGCIFGELLT 608
+ST D+WS G + E+
Sbjct: 181 FSTQSDVWSFGVVLWEIFA 237
>07836
Length = 1478
Score = 43.9 bits (102), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 53/190 (27%), Positives = 85/190 (44%), Gaps = 20/190 (10%)
Frame = -1
Query: 437 EIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIV--TVREIVVGSNMDKIYIVMNYV 494
E VA+K +E F T L + T+L +H NI+ +I + +++++ +Y
Sbjct: 1475 ENVAVKIFFTTEEASWFRETELYQ--TVL-LRHENILGFIAADIKGTGSWTQLFLITDY- 1308
Query: 495 EHDLKSLMETMKQPFL-PGEVKTLMIQLLRGVKHLHDNW--------ILHRDLKTSNLLL 545
H+ SL + + L E+ L + G+ HLH I HRD+K+ N+L+
Sbjct: 1307 -HENGSLHDYLLSRVLDSSEMLALAHSAICGLAHLHIEIFGTRGKPAIAHRDIKSKNILV 1131
Query: 546 SHAGILKVGDFGLAREYGSPLK----AYTPVVVTQWYRAP---ELLLGAKEYST--AVDM 596
G + D GLA Y S A P T+ Y AP E+LL K + DM
Sbjct: 1130 KKNGTCCIADLGLAVRYISESNEVDVAPNPRQGTKRYMAPEVLEMLLNVKNFDAFKQADM 951
Query: 597 WSVGCIFGEL 606
++ G + E+
Sbjct: 950 YAFGLVMWEI 921
>17975
Length = 449
Score = 43.5 bits (101), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 35/146 (23%), Positives = 67/146 (45%), Gaps = 10/146 (6%)
Frame = +3
Query: 424 YGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSN 483
+ VV A+ T E VA+K + K E +E+ + QHPN+V + E++
Sbjct: 6 FAVVKLARHVFTGEKVAVKVIDKTKLDEVSRSHLFQEVRCMKLVQHPNVVRLYEVI--DT 179
Query: 484 MDKIYIVM---------NYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWIL 534
K+Y+++ +Y+ L E + + + Q++ + + H ++
Sbjct: 180 QTKLYLILELGDGGDMYDYIMRHSGGLEEKLAKRYFR--------QIVEAISYCHKLHVV 335
Query: 535 HRDLKTSNLLLSHA-GILKVGDFGLA 559
HRDLK N++ G++K+ DFG +
Sbjct: 336 HRDLKPENVVFFEKPGLVKLTDFGFS 413
>21433
Length = 590
Score = 42.0 bits (97), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 33/94 (35%), Positives = 50/94 (53%)
Frame = +2
Query: 518 MIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQW 577
+ QL +++ H ++HRD+K NLLL G LK+ DFG + +P T + T
Sbjct: 185 IYQLSSALEYCHYRKVIHRDIKPENLLLGLKGDLKIADFGWSVH--APSSRRTTMCGTLD 358
Query: 578 YRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKP 611
Y PE++ G K + VD+WS+G + E L P
Sbjct: 359 YLPPEMVEG-KTHDENVDLWSLGVLCYEFLVGTP 457
>07291
Length = 833
Score = 41.6 bits (96), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 28/96 (29%), Positives = 50/96 (52%), Gaps = 6/96 (6%)
Frame = +1
Query: 520 QLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGS--PLKAYT----PVV 573
Q+ G+ +L + ++HR+L N +++ G L++ D+G+ GS P YT P
Sbjct: 73 QIADGMAYLQEVKVVHRNLAARNCIVTEDGRLQLSDYGVT---GSLFPQSYYTADDSPAR 243
Query: 574 VTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQ 609
+ APE + +S+ D+W+ G + ELLT+
Sbjct: 244 DLVKWMAPE-TIDNFHFSSKSDVWAFGVVLWELLTR 348
>15549
Length = 470
Score = 39.7 bits (91), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 15/39 (38%), Positives = 29/39 (74%)
Frame = -1
Query: 408 RSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKM 446
R +EF+C+ ++ +G YG+V+RAK+K ++ A+KR+ +
Sbjct: 227 RFADEFECIEQMGKGGYGIVFRAKNKVDEQEYAVKRIAL 111
>02638
Length = 1490
Score = 39.7 bits (91), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 18/50 (36%), Positives = 30/50 (60%)
Frame = +1
Query: 578 YRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFK 627
+ APE+L G + Y A D+WSVGC+ E+ T +P + + + + +FK
Sbjct: 34 FMAPEVLRG-ESYGRACDVWSVGCVMIEMCTCRPPWNSHDISNHLALIFK 180
>14477
Length = 493
Score = 39.3 bits (90), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 41/147 (27%), Positives = 70/147 (47%), Gaps = 4/147 (2%)
Frame = -1
Query: 418 RIEEGTYGVVYRAKDKKTD-EI-VALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTV 475
++ G +G V + + D EI VA+K LK ++E + K H +IV +
Sbjct: 469 KLGAGNFGSVMKGVCRLDDREIPVAIKVLKNADLDPSVQSELIKEAEVMKKMDHMHIVRL 290
Query: 476 REIVVGSNMDKIYIVMNYVEHDLKSLMETM-KQPFLP-GEVKTLMIQLLRGVKHLHDNWI 533
+ G M +V+ + L L + + K LP + LM Q+ +G+++L N
Sbjct: 289 IGLCEGETM---MLVLELAK--LGPLNKFLPKNKHLPLWNILELMWQVSQGMEYLEANKF 125
Query: 534 LHRDLKTSNLLLSHAGILKVGDFGLAR 560
+HRDL N+LL K+ DFG+++
Sbjct: 124 VHRDLAARNILLCDEHFAKISDFGMSK 44
>26009
Length = 886
Score = 32.3 bits (72), Expect(2) = 0.007, Method: Compositional matrix adjust.
Identities = 12/33 (36%), Positives = 22/33 (66%)
Frame = +3
Query: 513 EVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLL 545
E K++M QL+ + +H ++HRD+K N+L+
Sbjct: 714 EAKSVMKQLVSALDFMHSKQLVHRDIKPENVLI 812
Score = 25.8 bits (55), Expect(2) = 0.007, Method: Compositional matrix adjust.
Identities = 23/93 (24%), Positives = 35/93 (37%), Gaps = 5/93 (5%)
Frame = +2
Query: 411 EEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREIN-----TIL 465
E + + GTYG V A+ + T VALK L T LRE +
Sbjct: 416 EHYDVCKELGRGTYGKVVLARCRHTGTQVALKLLPKS-------CTKLREFQREFQLSYF 574
Query: 466 KAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDL 498
+ H NI+ + + ++ + V DL
Sbjct: 575 LSPHANIIDTYNVAFQTRSSYVFAQEHAVLGDL 673
>18481
Length = 437
Score = 39.3 bits (90), Expect = 0.007, Method: Composition-based stats.
Identities = 28/99 (28%), Positives = 46/99 (46%), Gaps = 3/99 (3%)
Frame = -1
Query: 467 AQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVK 526
+HP + T+ G+ +VM + L+ L K+ F + + QLL ++
Sbjct: 326 GRHPGLPTMYH--YGTEKHFNALVMELLGPSLEELFVICKRRFTLKTILMVSDQLLSRLE 153
Query: 527 HLHDNWILHRDLKTSNLLLS---HAGILKVGDFGLAREY 562
+H +HRDLK N L+ H L + DFGL++ Y
Sbjct: 152 FIHQKCFIHRDLKPDNFLMGLGRHCHRLYIIDFGLSKRY 36
>37602
Length = 804
Score = 38.9 bits (89), Expect = 0.007, Method: Compositional matrix adjust.
Identities = 20/72 (27%), Positives = 39/72 (54%)
Frame = -1
Query: 485 DKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLL 544
+K++I M Y + + P ++ + + L+G+ +LH +HRD+K +N+L
Sbjct: 300 EKLWIAMEYCGGGSMQDIYHVTGPLTEPQIAFVCRETLKGLHYLHRRGKMHRDIKGANIL 121
Query: 545 LSHAGILKVGDF 556
L+ G +K+ DF
Sbjct: 120 LTEEGDVKLADF 85
Score = 28.5 bits (62), Expect = 9.5, Method: Compositional matrix adjust.
Identities = 13/36 (36%), Positives = 21/36 (58%)
Frame = -2
Query: 396 ELPKYLPALQGCRSVEEFQCLNRIEEGTYGVVYRAK 431
E K +Q +++F+ + R+ GTYG VY+AK
Sbjct: 554 EYKKMQADIQRRNPLDDFELIQRVGSGTYGDVYKAK 447
>16708
Length = 1397
Score = 38.9 bits (89), Expect = 0.007, Method: Compositional matrix adjust.
Identities = 16/52 (30%), Positives = 31/52 (59%)
Frame = -1
Query: 511 PGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREY 562
P V + Q + ++H+H+ ++H D+K N+L+ G K+ D+G+A+ Y
Sbjct: 1097 PAMVCCIAGQXVCALEHIHELGVVHMDVKADNVLVDAHGNCKLTDYGIAQLY 942
>13078
Length = 773
Score = 37.7 bits (86), Expect = 0.018, Method: Compositional matrix adjust.
Identities = 31/125 (24%), Positives = 59/125 (47%), Gaps = 14/125 (11%)
Frame = -1
Query: 590 YSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKI--------WPGYS 641
+S D+WS+GCI EL T LF + + + + + LG+ ++ + +
Sbjct: 746 WSQPCDVWSIGCIMFELYTGYTLFQTHDNKEHLAMMERILGSLPYRMAKKTKKQKYFYHG 567
Query: 642 ELPVVKKMTFSEHPYNNLR--KRFGALLSD----QGFDLMNKFLTYFPGRRISAEDGLKH 695
L +K + + +N++ +R+ + Q FDLM+K L+Y R S ++H
Sbjct: 566 RLDWDEKSSAGRYVRDNVKPLRRYVKDPDNEDHQQLFDLMDKMLSYEVSTRYSLRQAMRH 387
Query: 696 EYFRE 700
+FR+
Sbjct: 386 PFFRK 372
>00486
Length = 797
Score = 35.4 bits (80), Expect = 0.093, Method: Compositional matrix adjust.
Identities = 18/50 (36%), Positives = 27/50 (54%)
Frame = -2
Query: 578 YRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFK 627
Y APE+L + AVD WS+G + ++LT P F + I+K+ K
Sbjct: 760 YMAPEILTRTG-HGKAVDWWSLGALMYDMLTGSPPFTAENRKKTIDKILK 614
>36481
Length = 806
Score = 33.5 bits (75), Expect = 0.30, Method: Compositional matrix adjust.
Identities = 37/149 (24%), Positives = 66/149 (44%), Gaps = 6/149 (4%)
Frame = +2
Query: 403 ALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLK-MEKEKEGFPITSLREI 461
++G S + + EGT+G V + KD + +ALK +K ++K +E + EI
Sbjct: 338 TMRGTSSTNDMKLCPHWGEGTFGKVVQCKDLLKGDDIALKIIKNVDKYREAAKL----EI 505
Query: 462 NTILKAQ----HPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGE-VKT 516
N + K + H + V+ + + I + + + ++ P E V+
Sbjct: 506 NVLEKLREKDPHAKHMCVQMLDWFDYHGHVCISFHMLGLSVFDFLKDNSYGAYPIEQVRH 685
Query: 517 LMIQLLRGVKHLHDNWILHRDLKTSNLLL 545
+ QL V LH+N + H DLK N+L
Sbjct: 686 ISYQLCYAVNFLHENQLTHTDLKPENILF 772
>15931
Length = 447
Score = 30.4 bits (67), Expect = 2.7, Method: Compositional matrix adjust.
Identities = 13/31 (41%), Positives = 19/31 (61%)
Frame = +1
Query: 670 QGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 700
Q FDLM+K L+Y R S ++H +FR+
Sbjct: 70 QLFDLMDKMLSYEVSTRYSLRQAMRHPFFRK 162
>00145
Length = 2325
Score = 30.4 bits (67), Expect = 2.8, Method: Composition-based stats.
Identities = 18/46 (39%), Positives = 24/46 (52%), Gaps = 1/46 (2%)
Frame = -1
Query: 683 PGRRISAEDGLKHEYFRETP-LPIDPSMFPTWPAKSEQQRVKRGTS 727
P RIS DG + RE+P LP D + P P + Q+ V R T+
Sbjct: 2313 PQHRISQSDGESVDVQRESPLLPRDGAAVPQRPGPAAQEGVSRQTA 2176
>20152
Length = 445
Score = 29.6 bits (65), Expect = 4.2, Method: Compositional matrix adjust.
Identities = 14/33 (42%), Positives = 20/33 (60%)
Frame = +1
Query: 581 PELLLGAKEYSTAVDMWSVGCIFGELLTQKPLF 613
PE+LLG + AVD+WS+G I L+ + F
Sbjct: 1 PEILLGDSYDAPAVDVWSLGVILYMLVVGEAPF 99
>38560
Length = 479
Score = 29.3 bits (64), Expect = 6.4, Method: Composition-based stats.
Identities = 12/30 (40%), Positives = 18/30 (60%)
Frame = -3
Query: 578 YRAPELLLGAKEYSTAVDMWSVGCIFGELL 607
Y APEL+ G + + D+WS+G + LL
Sbjct: 387 YAAPELISGLEYLGSEADIWSMGVLLYALL 298
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000344418 | hsapiens_gene_ensembl | PITSLRE
serine/threonine-protein kinase CDC2L2 (EC 2.7.11.22)
(Galactosyltransferase-associated protein kinase p58/GTA) (Cell
division cycle 2-like protein kinase 2) (CDK11).
[Source:Uniprot/SWISSPROT;Acc:Q9UQ88]
(780 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
29581 292 4e-84
01060 229 4e-60
01756 222 4e-58
14126 219 3e-57
04591 195 5e-50
32000 170 2e-42
01707 162 4e-40
04138 151 1e-36
01966 118 3e-28
23319 103 3e-22
00300 95 1e-19
03294 87 2e-17
18921 86 7e-17
06405 83 3e-16
13592 82 6e-16
12721 82 1e-15
01718 80 5e-15
09606 77 2e-14
03508 77 4e-14
20559 66 1e-13
12453 74 2e-13
14420 73 4e-13
15910 71 2e-12
26560 68 1e-11
19761 65 8e-11
18484 65 9e-11
21578 64 2e-10
27546 63 5e-10
03240 62 1e-09
14116 62 1e-09
30755 61 1e-09
13066 61 2e-09
13212 61 2e-09
28638 61 2e-09
26909 60 3e-09
19094 59 8e-09
21808 58 1e-08
11185 57 4e-08
19301 56 7e-08
27405 56 7e-08
18287 56 7e-08
07940 55 8e-08
24241 55 9e-08
26711 55 1e-07
28157 55 1e-07
31489 55 2e-07
17253 53 4e-07
04852 53 6e-07
18401 52 1e-06
00715 52 1e-06
21079 51 2e-06
12672 51 2e-06
16003 50 2e-06
00392 50 3e-06
12786 50 4e-06
17300 49 5e-06
31885 47 2e-05
11780 46 7e-05
05084 45 1e-04
20640 44 2e-04
07836 44 3e-04
17975 44 4e-04
21433 42 0.001
07291 42 0.001
15549 40 0.003
02638 39 0.006
14477 39 0.008
26009 32 0.008
37602 39 0.008
16708 39 0.009
18481 38 0.014
13078 38 0.015
00486 35 0.090
36481 33 0.42
15931 30 2.6
00145 30 3.0
20152 30 3.9
38560 29 6.5
>29581
Length = 1278
Score = 292 bits (747), Expect(2) = 4e-84, Method: Compositional matrix adjust.
Identities = 133/261 (50%), Positives = 183/261 (70%)
Frame = -2
Query: 474 ILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLR 533
+L +H NIV ++E+VVG ++D +++VM Y E DL SL++ M PF +VK +++QLL+
Sbjct: 1193 LLNLRHQNIVQLQEVVVGKSLDSLFLVMEYCEQDLASLLDNMPAPFSESQVKCIVLQLLK 1014
Query: 534 GVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPEL 593
G+++LH+ +I+HRDLK SNLL++ G +K+ DFGLAR YG P K TP VVT WYRAPEL
Sbjct: 1013 GLRYLHEAFIIHRDLKVSNLLMTDKGCVKIADFGLARNYGKPQKPMTPKVVTLWYRAPEL 834
Query: 594 LLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSEL 653
L G+K +STA+DMWS GCI GELL KPL PG S++ QI + + LGTP++ IWPG+S+L
Sbjct: 833 LFGSKTHSTAIDMWSAGCILGELLGHKPLMPGRSDLQQIELIMELLGTPNDTIWPGFSQL 654
Query: 654 PVVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPL 713
P ++ T + PYNNLR F LS+ G L+N Y P +R +AED L+H YF+E P
Sbjct: 653 PAFEQFTLKKQPYNNLRHTF-PWLSESGIRLLNGLFMYHPQKRATAEDCLEHSYFKEQPY 477
Query: 714 PIDPSMFPTWPAKSEQQRVKR 734
P DP P++P Q R+KR
Sbjct: 476 PCDPEFMPSFP----QHRLKR 426
Score = 38.9 bits (89), Expect(2) = 4e-84, Method: Composition-based stats.
Identities = 17/35 (48%), Positives = 25/35 (71%)
Frame = -1
Query: 446 DEIVALKRLKMEKEKEGFPITSLREINTILKAQHP 480
+EIVALK+++M E+ G PI+ LREIN ++ P
Sbjct: 1278 NEIVALKKMRMTGERYGIPISGLREINIFAQSATP 1174
>01060
Length = 1800
Score = 229 bits (583), Expect = 4e-60, Method: Compositional matrix adjust.
Identities = 122/338 (36%), Positives = 204/338 (60%), Gaps = 2/338 (0%)
Frame = +1
Query: 398 LLPIELKQELPKYLPALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKME 457
LL + +K+ + + AL + +FQ +I EGTYGVVY+ + + T +A+K++++
Sbjct: 22 LLKLNIKRLMMDFETALS---DLTDFQ---KIGEGTYGVVYKCRHRATGRKLAMKKIRLR 183
Query: 458 KEKEGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQ 517
++G P +++REI + + +H NIV + ++++ +++++V ++ DLK ++ +
Sbjct: 184 GSEDGVPSSAIREIAMLRELRHTNIVCLEDVIMED--ERLFLVFEFLSMDLKMYIDKFPE 357
Query: 518 PFLPGE--VKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSP 575
+ VK+ + Q++ G+ H I+HRDLK NLL++H G +K+ DFG+AR + P
Sbjct: 358 GVVLDRRLVKSYVFQIVTGIXFCHQRRIVHRDLKPQNLLINHTGAIKIADFGMARTFALP 537
Query: 576 LKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKV 635
++AYT VVT WYRAPE+L+GA +YST VD+WS+G IF ++L + P+F G+SEIDQ+ K+
Sbjct: 538 VRAYTHEVVTLWYRAPEILMGASKYSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKI 717
Query: 636 FKELGTPSEKIWPGYSELPVVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGR 695
F+ +GTP+E+ WP + +LP M F L + L S G DL+ + L P +
Sbjct: 718 FRIIGTPTEQTWPEFHKLPAFNGM-FPLWKEGKLSETLTDLDS-LGLDLIERTLKCDPAQ 891
Query: 696 RISAEDGLKHEYFRETPLPIDPSMFPTWPAKSEQQRVK 733
RIS + L+H YF + P P+ P S R+K
Sbjct: 892 RISCKKMLQHAYFLNVDTSVKPVDVPS-PEHS*STRLK 1002
>01756
Length = 1858
Score = 222 bits (566), Expect = 4e-58, Method: Compositional matrix adjust.
Identities = 117/309 (37%), Positives = 187/309 (60%), Gaps = 10/309 (3%)
Frame = -3
Query: 417 CRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILK 476
C +++ L +I +GT+G V++A+ KKT ++VA+K++ M+ EKEGFPIT+LREI +
Sbjct: 1754 CDEDAKYEKLAKIGQGTFGEVFKARCKKTKQVVAMKKVLMDNEKEGFPITALREIKILQL 1575
Query: 477 AQHPNIVTVREIV----VGSNMDK--IYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQ 530
H N+V + EI +N K Y+V + EHDL L+ M F E+K +M Q
Sbjct: 1574 LNHENVVDLIEICSTKATSANRYKSMFYLVFEFCEHDLAGLLSNMSVVFNLPEIKEVMKQ 1395
Query: 531 LLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKA---YTPVVVTQW 587
L+ G+ ++H N ILHRD+K +N+L++ G+LK+ DFGLAR + L+ YT VVT W
Sbjct: 1394 LMNGLYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLW 1215
Query: 588 YRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIW 647
YR PELLLG + YSTA+D W GCI E+ T+ P+ G +E +Q+ + + G+ + ++W
Sbjct: 1214 YRPPELLLGDRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQNQLTLITQLCGSITPEVW 1035
Query: 648 PGYSELPVVKKMTFSEHPYNNLRKRFGALLSDQ-GFDLMNKFLTYFPGRRISAEDGLKHE 706
PG L + + + +++R + D DL++K L PG+R+++++ L H+
Sbjct: 1034 PGVERLELYNSLDLPQGNKRKVKERLRYYIKDAYALDLLDKLLALDPGKRVNSDEALSHD 855
Query: 707 YFRETPLPI 715
+F P P+
Sbjct: 854 FFWMDPEPL 828
>14126
Length = 1265
Score = 219 bits (559), Expect = 3e-57, Method: Compositional matrix adjust.
Identities = 125/299 (41%), Positives = 182/299 (60%), Gaps = 9/299 (3%)
Frame = +3
Query: 421 EEFQCLNRIEEGTYGVVYRAKD-KKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQ- 478
++++ + I G YG VY+A+D + E VA+KR+++ +EG P+ ++REI+ + + +
Sbjct: 189 QKYEEVAVIGNGAYGTVYKARDLRNQGEFVAMKRIRLNNTEEGMPMMAIREISMLKQLEQ 368
Query: 479 --HPNIVTVREIVVGSNMDK---IYIVMNYVEHDLKSLMETMKQPFL-PGEVKTLMIQLL 532
HPN+V + ++ + D+ + +V Y+EHDL + + P L P +K LM+QLL
Sbjct: 369 YEHPNVVRLLDVSHNTITDREIRLNLVFEYIEHDLATYLAKCPSPGLGPDRIKDLMLQLL 548
Query: 533 RGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPE 592
GV LH N I+HRDLK NLL+S G LK+ DFGLAR Y + A T VVVT WYR+PE
Sbjct: 549 NGVDFLHSNRIVHRDLKPQNLLISKDGRLKLADFGLARIYSFHM-ALTTVVVTLWYRSPE 725
Query: 593 LLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWP-GYS 651
+L+ A EY T+VD+WS GCIF EL T++ LF G+SE DQ+ K+F+ +G P WP G S
Sbjct: 726 VLMQA-EYGTSVDIWSCGCIFAELFTRRALFKGSSEFDQLKKIFEVIGLPPAGDWPEGVS 902
Query: 652 ELPVVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 710
V + +F P L+ + Q DLM K L + GRRIS+ + L H Y R+
Sbjct: 903 ----VHRNSFRPTPPVPLQTLVPE-MDPQAKDLMEKMLVFKSGRRISSRESLLHPYLRD 1064
>04591
Length = 1117
Score = 195 bits (496), Expect = 5e-50, Method: Compositional matrix adjust.
Identities = 102/267 (38%), Positives = 161/267 (60%), Gaps = 7/267 (2%)
Frame = -2
Query: 460 KEGFPITSLREINTILKAQHPNIVTVREIV------VGSNMDKIYIVMNYVEHDLKSLME 513
KEGFPIT+LREI + + +H N+V ++EI Y++ Y ++DL L+
Sbjct: 1101 KEGFPITALREIKILQQLEHENVVQLQEICHTQAGPYNRYKSTFYLIFEYCDYDLAGLLN 922
Query: 514 TMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYG 573
++ F + K LM QLL G+ ++H ILHRD+K +N+LL+ G+LK+ DFGL+R +
Sbjct: 921 NLRVKFSLADKKNLMSQLLNGLFYIHTKQILHRDIKAANILLTRDGVLKLADFGLSRPWV 742
Query: 574 SPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQIN 633
K T VVT WYR PELLLG +EY +DMW VGCI E+ ++KPL G SE Q++
Sbjct: 741 KS-KRLTNRVVTLWYRPPELLLGEREYGPEIDMWGVGCIMAEMWSRKPLMQGRSEQHQLS 565
Query: 634 KVFKELGTPSEKIWPGYSELPVVKKMTFSEHPYNNLRKRFGALLSD-QGFDLMNKFLTYF 692
+ G+ + ++WPG ++L + K+ + +++R LL + +G +L++ FL
Sbjct: 564 LITDLCGSLNAEVWPGVTKLELYGKLDLPQGKPRKVKERMLDLLKNKEGAELIDIFLRLD 385
Query: 693 PGRRISAEDGLKHEYFRETPLPIDPSM 719
PG+R++ ++ L H++F PLP PS+
Sbjct: 384 PGQRMNCDNALSHDFFWVDPLP-SPSL 307
>32000
Length = 644
Score = 170 bits (431), Expect = 2e-42, Method: Compositional matrix adjust.
Identities = 79/150 (52%), Positives = 106/150 (70%)
Frame = -1
Query: 561 LKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQK 620
+K+ DFGLAR +G P++ YT V+T WYRAPE+LLG + YS VD+WS+GCIF E++T++
Sbjct: 572 MKIADFGLARVFGLPVRTYTHEVITLWYRAPEILLGCRFYSVPVDIWSLGCIFVEMMTRR 393
Query: 621 PLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKMTFSEHPYNNLRKRFGALLSDQ 680
LFPG+SEIDQ+ ++F+ LGTP EK+WPG S+LP K TF + P NL LS
Sbjct: 392 ALFPGDSEIDQLYRIFRTLGTPDEKVWPGVSKLPDYKP-TFPKWPLKNLETVVS--LSKV 222
Query: 681 GFDLMNKFLTYFPGRRISAEDGLKHEYFRE 710
G DL+ + LTY P RRISA ++H YF +
Sbjct: 221 GLDLLKRMLTYNPNRRISARSAMRHPYFND 132
>01707
Length = 757
Score = 162 bits (410), Expect = 4e-40, Method: Compositional matrix adjust.
Identities = 81/221 (36%), Positives = 138/221 (62%)
Frame = +1
Query: 420 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 479
+E+++ + +I EG+YGVV++ ++K+T ++VA+K+ ++ ++REI + + +H
Sbjct: 61 MEKYEKIGKIGEGSYGVVFKCRNKETSQLVAIKKFVESEDDPLIKKIAMREIRMLKQLKH 240
Query: 480 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLH 539
PN+V R I V ++++V +YV+H L + ++ + VK ++ Q L V H
Sbjct: 241 PNLV--RLIEVFRRKKRLHLVFDYVDHTLLNELDRYPRGLPEPMVKRIIYQTLLAVNFCH 414
Query: 540 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKE 599
+HRD+K N+L++ G +K+ DFG AR P YT V T+WYRAPELL+G +
Sbjct: 415 QYNTIHRDVKPENILITRQGQVKLCDFGFARILTGPGDEYTDYVATRWYRAPELLVGDTQ 594
Query: 600 YSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELG 640
Y VD+W++GC+F ELLT + L+PG S++DQ++ + K LG
Sbjct: 595 YGPPVDVWAIGCVFAELLTGQALWPGRSDVDQLHLIRKTLG 717
>04138
Length = 800
Score = 151 bits (381), Expect = 1e-36, Method: Compositional matrix adjust.
Identities = 72/178 (40%), Positives = 111/178 (62%), Gaps = 6/178 (3%)
Frame = +1
Query: 537 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKA---YTPVVVTQWYRAPEL 593
++H N ILHRD+K +N+L++ G+LK+ DFGLAR + L+ YT VVT WYR PEL
Sbjct: 58 YIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRPPEL 237
Query: 594 LLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSEL 653
LLG + YSTA+D W GCI E+ T+ P+ G +E +Q+ + + G+ + ++WPG ++L
Sbjct: 238 LLGDRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQNQLTLITQLCGSITPEVWPGVTQL 417
Query: 654 PVVKKM--TFSEHPYNNLRKRFGALLSD-QGFDLMNKFLTYFPGRRISAEDGLKHEYF 708
+ ++ + N +R RF +L D G DL + L P +RISA++ L H++F
Sbjct: 418 SMYHQIKGALAAGRKNIIRDRFARILKDPYGLDLFERLLKMDPSQRISADEALNHDFF 591
>01966
Length = 1735
Score = 118 bits (296), Expect(2) = 3e-28, Method: Compositional matrix adjust.
Identities = 55/175 (31%), Positives = 107/175 (61%), Gaps = 2/175 (1%)
Frame = -1
Query: 440 AKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYI 499
+ + T +A+K++++ ++G P +++REI + + +H NIV + ++++ +++++
Sbjct: 1654 CRHRATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTNIVCLEDVIMED--ERLFL 1481
Query: 500 VMNYVEHDLKSLMETMKQPFLPGE--VKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSH 557
V ++ DLK ++ + + VK+ + Q++ G+ H I+HRDLK NLL++H
Sbjct: 1480 VFEFLSMDLKMYIDKFPEGVVLDRRLVKSYVFQIVTGINFCHQRRIVHRDLKPQNLLINH 1301
Query: 558 AGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCI 612
G +K+ DFG+AR + P++AYT VVT WYRAPE+L+G + + W+ G +
Sbjct: 1300 TGAIKIADFGMARTFALPVRAYTHEVVTLWYRAPEILMGPQ---STPPXWTCGAL 1145
Score = 25.4 bits (54), Expect(2) = 3e-28, Method: Composition-based stats.
Identities = 10/13 (76%), Positives = 12/13 (92%)
Frame = -2
Query: 426 LNRIEEGTYGVVY 438
L++I EGTYGVVY
Sbjct: 1695 LSKIGEGTYGVVY 1657
Score = 97.4 bits (241), Expect = 2e-20, Method: Compositional matrix adjust.
Identities = 54/138 (39%), Positives = 80/138 (57%)
Frame = -3
Query: 596 GAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPV 655
GA +YST VD+WS+G IF ++L + P+F G+SEIDQ+ K+F+ +GTP+E+ WP + +LP
Sbjct: 1187 GASKYSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKLPA 1008
Query: 656 VKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPI 715
M F L + L S G DL+ + L P +RIS + L+H YF +
Sbjct: 1007 FNGM-FPLWKEGKLSETLTDLDS-LGLDLIERTLKCDPAQRISCKKMLQHAYFLNVDTSV 834
Query: 716 DPSMFPTWPAKSEQQRVK 733
P P+ P +S R+K
Sbjct: 833 KPVDVPS-PEQS*STRLK 783
>23319
Length = 2235
Score = 103 bits (256), Expect = 3e-22, Method: Compositional matrix adjust.
Identities = 50/117 (42%), Positives = 72/117 (61%), Gaps = 1/117 (0%)
Frame = +3
Query: 597 AKEYSTAVDMWSVGCIFGELLTQ-KPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPV 655
AK YST++DMWS GCIF EL +PLFPGN + DQ+ ++FK LGTP+E WPG ++LP
Sbjct: 18 AKMYSTSIDMWSAGCIFAELANAGRPLFPGNDDDDQLKRIFKLLGTPTEDQWPGMTQLPN 197
Query: 656 VKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETP 712
+ F + ++ L+ +G DL+ L P R+SA++ L+H YF + P
Sbjct: 198 YR--MFPMYHVTTTWQQVVPKLNSKGRDLLQCLLVCCPSDRMSADEALQHPYFADLP 362
>00300
Length = 2318
Score = 94.7 bits (234), Expect = 1e-19, Method: Compositional matrix adjust.
Identities = 66/207 (31%), Positives = 108/207 (52%), Gaps = 13/207 (6%)
Frame = -1
Query: 427 NRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKA----QHPNI 482
N+I EG +G VY A + T E++ALK +K + + LRE+ +K QH N+
Sbjct: 1640 NKIGEGQFGKVYTAVNMSTGELMALKEMKFQPND----LQQLREMCDEIKIFEGIQHENL 1473
Query: 483 VTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNW 542
V + V + D++ + M Y D ++ E K ++ +++ V HLH+N
Sbjct: 1472 VKYYGVEV--HKDEMLMFMEYC--DTGTIEEAAKMGLPEYLIRRYTREIVLAVNHLHENS 1305
Query: 543 ILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTP-------VVVTQWYRAPELLL 595
I+HRD+K +N+ L+ G +K+GDFG + + LK++T +V T Y APE+
Sbjct: 1304 IVHRDIKGANIFLTSNGHVKLGDFGCSVK----LKSHTTMPGEFHNLVGTTAYMAPEVFT 1137
Query: 596 GAKE--YSTAVDMWSVGCIFGELLTQK 620
+ Y A D+WS+GC+ E+ T K
Sbjct: 1136 QNDQGGYGRAADIWSLGCVVIEMATGK 1056
>03294
Length = 1684
Score = 87.0 bits (214), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 49/130 (37%), Positives = 73/130 (56%)
Frame = -1
Query: 604 VDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKMTFSE 663
VD+WS+G IF ++L + P+F G+SEIDQ+ K+F+ +GTP+E+ WP + +LP M F
Sbjct: 1672 VDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKLPAFNGM-FPL 1496
Query: 664 HPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSMFPTW 723
L + L S G DL+ + L P +RIS + L+H YF + P P+
Sbjct: 1495 WKEGKLSETLTDLDS-LGLDLIERTLKCDPAQRISCKKMLQHAYFLNVDTSVKPVDVPS- 1322
Query: 724 PAKSEQQRVK 733
P S R+K
Sbjct: 1321 PEHS*STRLK 1292
>18921
Length = 697
Score = 85.5 bits (210), Expect = 7e-17, Method: Compositional matrix adjust.
Identities = 57/205 (27%), Positives = 109/205 (53%), Gaps = 6/205 (2%)
Frame = +2
Query: 423 FQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNI 482
F L ++ EG+YG V+++ K+T +++A+K++ ++ + + ++EI+ + + I
Sbjct: 35 FDILGKLGEGSYGSVFKSLHKETGQVLAIKQVPVDTDLQEI----IKEISIMQQCDSKYI 202
Query: 483 VTVREIVVGS---NMDKIYIVMNYV-EHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHL 538
V GS N D ++IVM Y + +M + + E+ T++ L+G+ +L
Sbjct: 203 VKYY----GSYFKNTD-LWIVMEYCGAGSVSDIMRLRNKTLVEREIATILYYTLKGLXYL 367
Query: 539 HDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELL--LG 596
H +HRD+K N+LL++ G K+ DFG+A + + V+ T ++ APE++ +G
Sbjct: 368 HSRRKIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTPYWMAPEVIQEIG 547
Query: 597 AKEYSTAVDMWSVGCIFGELLTQKP 621
Y D+WS+G E+ KP
Sbjct: 548 ---YDCVADIWSLGITALEMAEGKP 613
>06405
Length = 1965
Score = 83.2 bits (204), Expect = 3e-16, Method: Compositional matrix adjust.
Identities = 63/205 (30%), Positives = 102/205 (49%), Gaps = 8/205 (3%)
Frame = +1
Query: 422 EFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILK-AQHP 480
E +R+ G YG VY A K+ ++IVA+K LK ++ + E I+K +HP
Sbjct: 262 EIAMKHRLGGGQYGDVYEAMWKRYNKIVAVKTLK----EDTMALNDFLEEAAIMKEMKHP 429
Query: 481 NIVTVREIVVGSNMDKIYIVMNYVEHD--LKSLMETMKQPFLPGEVKTLMIQLLRGVKHL 538
N+V + + V + YIV ++ H L L + ++ P + + Q+ G+ +L
Sbjct: 430 NLVQL--LGVCTREPPFYIVTEFMPHGNLLDYLRSSTREENGPTALMYMATQIASGMAYL 603
Query: 539 HDNWILHRDLKTSNLLLSHAGILKVGDFGLAR-----EYGSPLKAYTPVVVTQWYRAPEL 593
+HRDL N L++ + ++KV DFGLAR Y + + A P+ +W APE
Sbjct: 604 ETKNFIHRDLAARNCLVADSNMVKVADFGLARLMKDDTYTAHIGAKFPI---KW-TAPE- 768
Query: 594 LLGAKEYSTAVDMWSVGCIFGELLT 618
L +ST D+W+ G + EL T
Sbjct: 769 GLAFNRFSTRSDIWAFGVLLWELAT 843
>13592
Length = 980
Score = 82.4 bits (202), Expect = 6e-16, Method: Compositional matrix adjust.
Identities = 80/295 (27%), Positives = 138/295 (46%), Gaps = 13/295 (4%)
Frame = +2
Query: 428 RIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVRE 487
+I +G +G VY A + T E++A+K + ++ + E+ + +H N+V
Sbjct: 5 KIGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETRALKNVAEELKILEGIKHKNLVRYYG 184
Query: 488 IVVGSNMDKIYIVMNYV-EHDLKSLMETMKQPFLPGEV-KTLMIQLLRGVKHLHDNWILH 545
I V + +++ I M E L+SL+E LP + + QLL GV LH + I+H
Sbjct: 185 IEV--HREELLIFMELCSEGTLESLVELTGG--LPEALSRRFTAQLLSGVAELHKHGIVH 352
Query: 546 RDLKTSNL-LLSHAGILKVGDFGLAREYGSPLKAYTPV-------VVTQWYRAPELL--L 595
RD+KT+N+ L+ + LK+GDFG A + ++A+T V V TQ Y APE+
Sbjct: 353 RDIKTANIFLVDGSNSLKLGDFGSAVK----IQAHTTVPGELQGYVGTQAYMAPEVFTKT 520
Query: 596 GAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGY-SELP 654
+ + D+WSVGC+ E+ + K + W + S
Sbjct: 521 NSDGHGRLADIWSVGCVVVEMASGK------------------------RPWAQFDSNFQ 628
Query: 655 VVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFR 709
++ K+ E P + LS +G D ++ L + P +R+SA + L+ + +
Sbjct: 629 IMFKVGMGEKP------QAPESLSQEGHDFIDHCLQHDPKQRLSAIELLEQNFCK 775
>12721
Length = 821
Score = 81.6 bits (200), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 53/196 (27%), Positives = 106/196 (54%)
Frame = +1
Query: 428 RIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVRE 487
+I EG+ G+V A + ++ A+K++ + K++ + E+ + HPNIV +
Sbjct: 109 KIGEGSTGIVCIATSRDGRQM-AVKKMDLRKQQRRELL--FNEVVVMRDYHHPNIVEMYN 279
Query: 488 IVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRD 547
+ + D++++VM ++E + + T + ++ T+ L+ + LH N ++HRD
Sbjct: 280 SYLVN--DELWVVMEFMEGGALTDIVTNNR-MDEVQIATVCRACLKALAFLHANGVIHRD 450
Query: 548 LKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMW 607
+K+ ++LLSH G +K+ DFG + L+ +V T ++ APE ++ Y VD+W
Sbjct: 451 IKSDSILLSHDGKVKLXDFGFCAQVTQDLQKRKSLVGTPYWMAPE-VISRLPYGPEVDIW 627
Query: 608 SVGCIFGELLTQKPLF 623
S+G + E++ +P F
Sbjct: 628 SLGIMVMEMIDAEPPF 675
>01718
Length = 959
Score = 79.7 bits (195), Expect = 5e-15, Method: Compositional matrix adjust.
Identities = 60/218 (27%), Positives = 107/218 (49%), Gaps = 6/218 (2%)
Frame = +3
Query: 413 ALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREIN 472
A+ +++F C +I G + V++ + T +++ALK M + LRE+
Sbjct: 126 AVSALTRLDDFIC-EKIGAGFFSEVFKVTHRITGQVMALKMNTMTSNRHNM----LREVQ 290
Query: 473 TILKAQHPNIVTVREIVVGSNMDKIYIVMNYV-EHDLKSLMETMKQPFLPGEVKTLMIQL 531
+ + QH NI+ + V +++ + Y+ +L+ L+E + + L + L
Sbjct: 291 LLNRLQHANILRFMGVCVHEG--QLHALTEYIPSGNLEQLLEKKDEELPWTQRIQLTLGL 464
Query: 532 LRGVKHLHDNWILHRDLKTSNLLL----SHAGILKVGDFGLAREYGSPL-KAYTPVVVTQ 586
RG+ +LH +HRDL + N+L+ +H + DFGLA + PL K P V +
Sbjct: 465 ARGLDYLHSTRFIHRDLTSKNILIRREDNHGYHAVIADFGLATKIPDPLDKEKLPTVGSP 644
Query: 587 WYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFP 624
++ APE+L G Y+ D++SVG I E+ + P P
Sbjct: 645 YWMAPEVLNG-HFYNERADLFSVGIIMCEITARIPADP 755
>09606
Length = 1300
Score = 77.4 bits (189), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 82/314 (26%), Positives = 134/314 (42%), Gaps = 24/314 (7%)
Frame = -3
Query: 420 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 479
+E F + +G + ++Y+ + K T VA+ + EK K ++R + I H
Sbjct: 1118 MENFVLYEELGKGEHSIIYKGRRKGTINFVAIHCI--EKCKRPEVTNTVRMTHDI---SH 954
Query: 480 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPF-LP-GEVKTLMIQLLRGVKH 537
PN+V E SN +++V+ SL + + Q LP ++ I L+ G+ +
Sbjct: 953 PNVVQFHEWYETSN--HLWLVVELCTGG--SLADILAQDHHLPETSIRDFGIHLVTGLHY 786
Query: 538 LHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAY------------------ 579
+H IL DL+ S +LL +G+LK DFGL++ G L+
Sbjct: 785 IHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQWNIQSAEE 606
Query: 580 ----TPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKV 635
P + Y APE+ GA E S D+W++GC+F E+ + P F G + +KV
Sbjct: 605 MMKQVPTSGSPTYMAPEVFQGA-EPSIMSDLWALGCVFYEMFSGHPPFLGETYDITKDKV 429
Query: 636 FKELGTPSEKIWPGYSELPVVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGR 695
K +P LP VK S P S + +L+ L R
Sbjct: 428 LN-------KEFP----LPKVKGSRLSAKP------------SPEFLNLLESLLQKDSTR 318
Query: 696 RISAEDGLKHEYFR 709
R+S +KH +++
Sbjct: 317 RLSWASLVKHAFWQ 276
>03508
Length = 1463
Score = 76.6 bits (187), Expect = 4e-14, Method: Compositional matrix adjust.
Identities = 39/122 (31%), Positives = 72/122 (59%), Gaps = 2/122 (1%)
Frame = +1
Query: 505 EHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGI-LKV 563
EH + + + Q F +++ + +L++ + H I+HRD+K N+++ H L++
Sbjct: 820 EHVNNTDFKQLYQTFTDYDIRFYLYELMKALDFCHSMGIMHRDVKPHNVMIDHENKKLRL 999
Query: 564 GDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQK-PL 622
D+GLA E+ P Y V +++++ PELLL + Y ++DMWS+GC+F ++ +K PL
Sbjct: 1000IDWGLA-EFYHPGMEYNVRVASRYFKGPELLLDYQMYDYSLDMWSLGCMFASMIFRKEPL 1176
Query: 623 FP 624
P
Sbjct: 1177LP 1182
Score = 35.0 bits (79), Expect = 0.11, Method: Compositional matrix adjust.
Identities = 27/114 (23%), Positives = 51/114 (44%), Gaps = 12/114 (10%)
Frame = +2
Query: 607 WSVG----CIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKMTFS 662
W+ G C+ + P F G+ DQ+ ++ K LGT + ++ + + F+
Sbjct: 1118 WTCGVWAACLPA*SSGKSPFFHGHDNYDQLVRIAKVLGT--DDLYGYIEKYQIDLDPRFN 1291
Query: 663 EHPYNNLRKRF--------GALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYF 708
+ + RKR+ L+S + D ++K L Y R++A + + H YF
Sbjct: 1292 DILGRHSRKRWERFVHSENQHLISPEALDFLDKLLRYDHNERLTAREAMDHPYF 1453
>20559
Length = 430
Score = 65.9 bits (159), Expect(2) = 1e-13, Method: Compositional matrix adjust.
Identities = 31/82 (37%), Positives = 58/82 (70%)
Frame = -2
Query: 408 PKYLPALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITS 467
P +L + +++++ L +I EGTYG V++AK+++T EIVALKR++++ + EG P ++
Sbjct: 414 PTHLHSF*LKHKMQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSA 235
Query: 468 LREINTILKAQHPNIVTVREIV 489
LREI + + +H NIV + +++
Sbjct: 234 LREICLLKELKHRNIVRLHDVL 169
Score = 29.3 bits (64), Expect(2) = 1e-13, Method: Composition-based stats.
Identities = 14/36 (38%), Positives = 19/36 (52%)
Frame = -3
Query: 503 YVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHL 538
Y + DLK +T P VK+ + QLLRG+ L
Sbjct: 134 YCDQDLKKYFDTCNGEIDPDTVKSFLHQLLRGLGFL 27
>12453
Length = 680
Score = 74.3 bits (181), Expect = 2e-13, Method: Composition-based stats.
Identities = 41/100 (41%), Positives = 55/100 (55%)
Frame = +3
Query: 609 VGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKMTFSEHPYNN 668
VGCIF E+ +PLFPG++ D+++ +FK LGTP+E P S P + +
Sbjct: 6 VGCIFYEMACGRPLFPGSTVEDELHLIFKTLGTPTEDSLPSISRNPDFLALNLPHYQGEA 185
Query: 669 LRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYF 708
L L SD G DL+ KFL Y R+SA D LKH +F
Sbjct: 186 LITIAPRLDSD-GLDLLAKFLKYNAKIRVSAADSLKHSFF 302
>14420
Length = 528
Score = 73.2 bits (178), Expect = 4e-13, Method: Compositional matrix adjust.
Identities = 44/156 (28%), Positives = 90/156 (57%), Gaps = 2/156 (1%)
Frame = +2
Query: 468 LREINTILKAQHPNIVT-VREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLP-GEVK 525
+ EI + + Q+PNIV + +VG +++++VM ++ SL + + + + G++
Sbjct: 44 INEILVMRENQNPNIVNYLDSYLVG---EELWVVMEFLAGG--SLTDVVTETCMDEGQIA 208
Query: 526 TLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVT 585
+ + L+ ++ LH+N ++HRD+K+ N+LL G +K+ DFG + + +V T
Sbjct: 209 AVCRECLQALEFLHENQVIHRDIKSDNILLGMDGSVKLTDFGFCAQLSPEQSKRSTMVGT 388
Query: 586 QWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKP 621
++ APE ++ K+Y VD+WS+G + E++ +P
Sbjct: 389 PYWMAPE-VVTRKQYGPTVDIWSLGVMCIEMIEGEP 493
>15910
Length = 1361
Score = 70.9 bits (172), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 49/125 (39%), Positives = 67/125 (53%), Gaps = 3/125 (2%)
Frame = +2
Query: 531 LLRGVKHLHDNWILHRDLKTSNLL---LSHAGILKVGDFGLAREYGSPLKAYTPVVVTQW 587
+L GV+++H N ++HRDLK NLL ++ LK+ DFGL+R P + V T
Sbjct: 491 ILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLADFGLSRII-EPEVQMSTVCGTPG 667
Query: 588 YRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIW 647
Y APE+L G K Y+ +VDMWSVG I LL F +E + K+ K E+ W
Sbjct: 668 YCAPEVLKGDK-YTPSVDMWSVGVIAYILLCGYEPFFAENEFEMYRKIIKGEYKFDEEYW 844
Query: 648 PGYSE 652
SE
Sbjct: 845 SEISE 859
>26560
Length = 398
Score = 68.2 bits (165), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 37/119 (31%), Positives = 66/119 (55%), Gaps = 4/119 (3%)
Frame = -1
Query: 519 FLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKA 578
F EV+ +++ G++H+H ++++RDLK +N+LL G +++ D GLA ++ K
Sbjct: 365 FTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGLACDFSK--KR 192
Query: 579 YTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLF----PGNSEIDQIN 633
V T Y APE+L+ + Y ++ D +S GC+ +LL F G + ID++
Sbjct: 191 PHASVGTHGYMAPEVLMKGQSYDSSADWFSFGCMLYKLLKGHSPFRQHNQGQARIDRMT 15
>19761
Length = 473
Score = 65.5 bits (158), Expect = 8e-11, Method: Compositional matrix adjust.
Identities = 36/104 (34%), Positives = 60/104 (57%)
Frame = -3
Query: 537 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLG 596
H H ILHRDLK N+ ++ G +++GD GLAR+ P T V T Y +PE +L
Sbjct: 372 HTHTPVILHRDLKPQNIYVTEKGDVRLGDLGLARKLTGPADFATSQVGTIMYLSPE-ILS 196
Query: 597 AKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELG 640
+ Y++ D+WS+GC+F ++ +K G+ E+ + + + +G
Sbjct: 195 QQPYNSKSDIWSLGCVFYDITGKK----GSDEMGVMFLLVQVMG 76
>18484
Length = 635
Score = 65.5 bits (158), Expect = 9e-11, Method: Compositional matrix adjust.
Identities = 35/99 (35%), Positives = 55/99 (55%)
Frame = +1
Query: 530 QLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYR 589
++ G+ LHD I++RDLK N++L G +K+ DFG+ +E + T Y
Sbjct: 67 EIAVGLFFLHDQGIIYRDLKLDNVMLDSEGHIKIADFGMCKEGMTGDATTRTFCGTPDYI 246
Query: 590 APELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSE 628
APE++L + YS +VD W+ G + E+L +P F G E
Sbjct: 247 APEIVL-YQPYSKSVDWWAYGVLLFEMLAGQPPFDGEDE 360
>21578
Length = 524
Score = 64.3 bits (155), Expect = 2e-10, Method: Composition-based stats.
Identities = 26/33 (78%), Positives = 31/33 (93%)
Frame = +2
Query: 403 LKQELPKYLPALQGCRSVEEFQCLNRIEEGTYG 435
LK++LP YLPA+QGCR+VEEF C+NRIEEGTYG
Sbjct: 425 LKEDLPVYLPAIQGCRNVEEFHCMNRIEEGTYG 523
>27546
Length = 426
Score = 62.8 bits (151), Expect = 5e-10, Method: Composition-based stats.
Identities = 38/113 (33%), Positives = 60/113 (53%), Gaps = 2/113 (1%)
Frame = -1
Query: 460 KEGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQ-- 517
K+ FP RE+ + + HPNI+ + I+ KI+I M Y E ++ +K+
Sbjct: 348 KKFFP----RELEILTRLDHPNIIQIHSIL--QRGPKIFIFMRYAEKG--DMLSHIKKTG 193
Query: 518 PFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAR 570
P + K Q+ + +++LH + I HRDLK N+LLS +K+ DFG AR
Sbjct: 192 PIDEAQTKVWFFQMAKALQYLHSHDIAHRDLKCENILLSKRLNVKIADFGFAR 34
>03240
Length = 1683
Score = 61.6 bits (148), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 62/262 (23%), Positives = 105/262 (40%), Gaps = 48/262 (18%)
Frame = -3
Query: 423 FQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNI 482
F+ + + G +G V + T + A+K L+ + + ++ IL A+ N
Sbjct: 1285 FEKIKTLGVGAFGEVSLCRKNDTGMLYAMKTLRKSDVLKRNQVAHVKAERDIL-AEADNE 1109
Query: 483 VTVREIVVGSNMDKIYIVMNYVEH-DLKSL---METMKQPFLPGEVKTLMIQLLRGVKHL 538
V+ + + +Y VM+YV DL L ME + +P + + +L++ ++ +
Sbjct: 1108 WVVKLYYSFQDHNYLYFVMDYVPGGDLMGLLIRMEILDEPL----ARFYVAELVQAIESV 941
Query: 539 HDNWILHRDLKTSNLLLSHAGILKVGDFGL-------------------AREYGSPLKAY 579
H +HRD+K N+L+ G +K+ DFGL AR+ +K
Sbjct: 940 HRMGFIHRDIKPDNILIDRNGHIKLTDFGLCTGFRWTHNSKYYQRDGTHARQDSMEVKCQ 761
Query: 580 T-------------------------PVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFG 614
+V T Y APE+L Y++ D WSVG I
Sbjct: 760 LDEQCQCEILKPLERRRKREQRCLAHSLVGTPNYIAPEVLSRLGGYTSVCDWWSVGVILF 581
Query: 615 ELLTQKPLFPGNSEIDQINKVF 636
E+L P F N+ + KV
Sbjct: 580 EMLVGHPPFYANTPAETQYKVI 515
>14116
Length = 1017
Score = 61.6 bits (148), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 61/205 (29%), Positives = 99/205 (48%), Gaps = 14/205 (6%)
Frame = -1
Query: 429 IEEGTYGVVYRA----KDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVT 484
I +G +G V R ++K D +VA+K L +E + L+E + H N++T
Sbjct: 612 IGKGNFGCVKRGFLTLPEQKGDILVAVKTLHNNNPREIELQSFLQEALIMKDFHHSNVLT 433
Query: 485 VREIVVGSNMDKI-YIVMNYVEHD--LKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDN 541
+ I + N+D + +V+ +++H L + + QP + ++ + + RG+ +L
Sbjct: 432 LIGICL--NLDDMPLVVLPFMKHGDLLTYIRDDQHQPTIK-DLIMYGVDIARGMDYLAGL 262
Query: 542 WILHRDLKTSNLLLSHAGILKVGDFGLAR-----EYGSP--LKAYTPVVVTQWYRAPELL 594
+HRDL N +L +KV DFGLAR EY S KA PV +W L
Sbjct: 261 KFVHRDLAARNCMLDEDFHVKVADFGLARDIYEKEYYSSENKKAKLPV---KWMALESLE 91
Query: 595 LGAKEYSTAVDMWSVGCIFGELLTQ 619
G Y + D+WS G + ELLT+
Sbjct: 90 KG--NYDSKTDVWSYGVVLWELLTR 22
>30755
Length = 1137
Score = 61.2 bits (147), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 35/94 (37%), Positives = 51/94 (54%), Gaps = 3/94 (3%)
Frame = +2
Query: 530 QLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLARE---YGSPLKAYTPVVVTQ 586
+++ + +LH I++RDLK NLLL G +KV DFGL +E YG K + T
Sbjct: 56 EIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCKEDITYGRTTKTFCG---TP 226
Query: 587 WYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQK 620
Y APE +L +Y AVD W G + E++ +
Sbjct: 227 EYLAPE-VLDDNDYGRAVDWWGTGVVMYEMICGR 325
>13066
Length = 551
Score = 61.2 bits (147), Expect = 2e-09, Method: Composition-based stats.
Identities = 52/185 (28%), Positives = 87/185 (47%), Gaps = 6/185 (3%)
Frame = +3
Query: 432 GTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREIVVG 491
GT+ Y K +I+ ++ ++ ++ FP RE++ + K HP I+ + I+
Sbjct: 24 GTFNDGYGRNIKLACKIIDKEKAPVDFVEKFFP----RELDLLTKLDHPYIIQIHSIL-- 185
Query: 492 SNMDKIYIVMNYVEH-DLKSLMETMKQPFLP-GEVKTLMIQLLRGVKHLHDNWILHRDLK 549
K +I M + E DL + ++ + F+ + K Q+ + +LH + HRDLK
Sbjct: 186 QRXPKNFIFMRFAERGDLLTYIQEVG--FVKEKQAKIWFYQMTTALNYLHSYDVAHRDLK 359
Query: 550 TSNLLLSHAGILKVGDFGLA----REYGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVD 605
N+LLS +K+ DFG A E G + T + Y APE++ GA D
Sbjct: 360 CENILLSSHFNVKLADFGFACACITESGEKYMSRT-YCGSAAYAAPEIVYGAPYAPKVAD 536
Query: 606 MWSVG 610
WS+G
Sbjct: 537 AWSLG 551
>13212
Length = 1067
Score = 61.2 bits (147), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 46/206 (22%), Positives = 93/206 (45%), Gaps = 4/206 (1%)
Frame = -1
Query: 508 LKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFG 567
L S+M +++P ++ + ++ + LH + ++HRD+K N+LL+ G +K+ DFG
Sbjct: 1022 LDSIMVDLEKPMTEAQICYVCHEMCMALDFLHRHHVIHRDIKAGNVLLTIDGEVKLADFG 843
Query: 568 LAREYGSPLKAYTPVVVTQWYRAPELLLGA----KEYSTAVDMWSVGCIFGELLTQKPLF 623
++ + + + T ++ APE++L Y D+WS+G E
Sbjct: 842 VSAKNTQTQQKRDTFIGTPYWMAPEVVLCETLKDTPYDFKADIWSLGVTLIE-------- 687
Query: 624 PGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKMTFSEHPYNNLRKRFGALLSDQGFD 683
F ++ P++++ P + V+ K+ S+ P K++ L D
Sbjct: 686 ------------FAQIEPPNKEMHP----MRVLIKIHKSDPPTLEKPKKWTKLFK----D 567
Query: 684 LMNKFLTYFPGRRISAEDGLKHEYFR 709
+ K L P R +A + L+H + +
Sbjct: 566 FIAKCLVKDPNLRPTAAELLEHPFMK 489
>28638
Length = 1458
Score = 60.8 bits (146), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 33/81 (40%), Positives = 51/81 (62%), Gaps = 2/81 (2%)
Frame = -1
Query: 543 ILHRDLKTSNLLLSHA--GILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEY 600
I+H DLK N+LL + +K+ DFG + + G + Y + +++YR+PE+LLG Y
Sbjct: 768 IIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQY---IQSRFYRSPEVLLGVP-Y 601
Query: 601 STAVDMWSVGCIFGELLTQKP 621
A+DMWS+GCI E+ T +P
Sbjct: 600 DLAIDMWSLGCILVEMHTGEP 538
Score = 30.0 bits (66), Expect = 3.9, Method: Compositional matrix adjust.
Identities = 15/52 (28%), Positives = 22/52 (42%), Gaps = 5/52 (9%)
Frame = -2
Query: 600 YSTAVDMWSVGC-----IFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKI 646
Y W + C + PLF G++E DQ+ K+ + LG P I
Sbjct: 617 YXXCPMTWPLTCGXWAVYWWRCTXGNPLFAGSNEFDQMMKIVEVLGVPPRHI 462
>26909
Length = 394
Score = 60.1 bits (144), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 38/119 (31%), Positives = 57/119 (47%), Gaps = 16/119 (13%)
Frame = +2
Query: 612 IFGELLTQKPLFPGNSEI---------DQINKVFKELGTPSEKIWPGYSELPVVKKMT-- 660
IF ELLT +P+F E DQ++++F +G P EK W +P +++T
Sbjct: 2 IFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFPQEKDWEDIRRMPEHQQLTKD 181
Query: 661 FSEHPYNNLR-----KRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLP 714
F Y N ++ + F L+ K LT P +RI++E +K YF E PLP
Sbjct: 182 FKRSSYVNCNLMKYMEKHKVKADSKAFHLLQKLLTMDPVKRITSEQAMKDPYFLEEPLP 358
>19094
Length = 898
Score = 58.9 bits (141), Expect = 8e-09, Method: Compositional matrix adjust.
Identities = 31/105 (29%), Positives = 58/105 (55%), Gaps = 2/105 (1%)
Frame = +1
Query: 508 LKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFG 567
+ +M + + E+ T++ L+G+ +LH +HRD+K N+LL++ G K+ DFG
Sbjct: 16 VSDIMRLRNKTLVEREIATILYYTLKGL*YLHSRRKIHRDIKAGNILLNNEGHAKLADFG 195
Query: 568 LAREYGSPLKAYTPVVVTQWYRAPELL--LGAKEYSTAVDMWSVG 610
+A + + V+ T ++ APE++ +G Y D+WS+G
Sbjct: 196 VAGQLTDTMAKRNTVIGTPYWMAPEVIQEIG---YDCVADIWSLG 321
>21808
Length = 1011
Score = 58.2 bits (139), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 56/201 (27%), Positives = 96/201 (47%), Gaps = 14/201 (6%)
Frame = +1
Query: 449 VALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDL 508
VA+K LK P L E + K +HP ++ + V + D I+I+ +++
Sbjct: 28 VAIKTLKSGTMD---PKDFLAEAQIMKKLRHPKLIQL--YAVCTQDDPIFIITELMKNG- 189
Query: 509 KSLMETMKQPFLPGEVKTLMI--------QLLRGVKHLHDNWILHRDLKTSNLLLSHAGI 560
SL+E FL G+ + L + Q+ G+ +L +HRDL N+L+S
Sbjct: 190 -SLLE-----FLQGKGRVLKLPALIDIGAQIACGMAYLESQNYIHRDLAARNILVSDNNT 351
Query: 561 LKVGDFGLAR-----EYGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGE 615
+K+ DFGLAR EY + + A P+ +W APE ++ D+WS G + E
Sbjct: 352 VKIADFGLARVIKEDEYEARVGARFPI---KW-TAPE-AANYNRFTIKSDVWSFGILLTE 516
Query: 616 LLTQKPL-FPGNSEIDQINKV 635
+T + +PG + + +++V
Sbjct: 517 TVTYGRVPYPGMTNAEVLHQV 579
>11185
Length = 473
Score = 56.6 bits (135), Expect = 4e-08, Method: Compositional matrix adjust.
Identities = 35/117 (29%), Positives = 56/117 (47%), Gaps = 22/117 (18%)
Frame = +1
Query: 524 VKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAY---- 579
++ I L+ G+ ++H IL DL+ S +LL +G+LK DFGL++ G L+
Sbjct: 7 IRDFGIHLVTGLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKF 186
Query: 580 ------------------TPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLT 618
P + Y APE+ GA E S D+W++GC+F E+ +
Sbjct: 187 AEAGDQWNIQSAEEMMKQVPTSGSPTYMAPEVFQGA-EPSIMSDLWALGCVFYEMFS 354
>19301
Length = 712
Score = 55.8 bits (133), Expect = 7e-08, Method: Compositional matrix adjust.
Identities = 43/149 (28%), Positives = 75/149 (50%), Gaps = 2/149 (1%)
Frame = +2
Query: 421 EEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHP 480
E L + G G V+ K E VA+K+++ KE + I +LR++N HP
Sbjct: 305 ESITDLEWLGSGAQGAVFLGK--LCAEEVAVKKVRDIKETD---IRNLRKLN------HP 451
Query: 481 NIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMK--QPFLPGEVKTLMIQLLRGVKHL 538
NI++ + + + I+M Y + L E ++ + P V Q+ G+ +L
Sbjct: 452 NIISFKGVC--TQAPCYCIIMEYCPYG--QLYEVLRDGKEIPPALVLDWSKQIASGMNYL 619
Query: 539 HDNWILHRDLKTSNLLLSHAGILKVGDFG 567
H + I+HRDLK+ N+L++ ++K+ DFG
Sbjct: 620 HSHKIIHRDLKSPNVLVAKNDVVKISDFG 706
>27405
Length = 532
Score = 55.8 bits (133), Expect = 7e-08, Method: Compositional matrix adjust.
Identities = 28/87 (32%), Positives = 51/87 (58%)
Frame = -3
Query: 519 FLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKA 578
F EV+ +++ G++H+H ++++RDLK +N+LL G +++ D GLA ++ K
Sbjct: 263 FTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGLACDFSK--KK 90
Query: 579 YTPVVVTQWYRAPELLLGAKEYSTAVD 605
V T Y APE+L+ + Y ++ D
Sbjct: 89 PHASVGTHGYMAPEVLMKGQAYDSSAD 9
>18287
Length = 678
Score = 55.8 bits (133), Expect = 7e-08, Method: Composition-based stats.
Identities = 35/119 (29%), Positives = 53/119 (44%), Gaps = 8/119 (6%)
Frame = -3
Query: 600 YSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKM 659
Y ++D+WSVGCIF ELL+++ LF + Q++ + +GTP + E
Sbjct: 673 YDYSIDIWSVGCIFAELLSRRILFQAQGPVQQLDMIINLVGTPRPEDMERACE------- 515
Query: 660 TFSEHPYNNLRKRFGALL--------SDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 710
H N +R L + + L+ + L P RISAE+ L H Y E
Sbjct: 514 GARNHILNQPFRRQNLLTLYNLSPHATHEAVRLLTRMLILNPKNRISAEEALSHPYLDE 338
>07940
Length = 1336
Score = 55.5 bits (132), Expect = 8e-08, Method: Compositional matrix adjust.
Identities = 34/112 (30%), Positives = 57/112 (50%), Gaps = 6/112 (5%)
Frame = -3
Query: 513 ETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLARE- 571
+ M + P ++ + Q+ RG+++L +HRDL N+L++ +LK+ DFGL R
Sbjct: 374 QDMLKMLTPKDLISYAYQVARGMEYLASKQCIHRDLAARNVLVAEEYVLKIADFGLTRNL 195
Query: 572 -----YGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLT 618
Y PV +W APE L ++Y++ D+WS G + E+ T
Sbjct: 194 QQFDYYRKTTDGRLPV---KW-MAPEALFD-RKYTSKSDVWSYGVLLWEIFT 54
>24241
Length = 413
Score = 55.5 bits (132), Expect = 9e-08, Method: Compositional matrix adjust.
Identities = 25/84 (29%), Positives = 54/84 (64%)
Frame = -2
Query: 426 LNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTV 485
L++I EGTYGVVY+ + + T +A+K++++ ++G P +++REI + + +H +
Sbjct: 328 LSKIGEGTYGVVYKCRHRATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTQXLVC 149
Query: 486 REIVVGSNMDKIYIVMNYVEHDLK 509
E V+ + +++++V ++ DLK
Sbjct: 148 LEDVIMED-ERLFLVFEFLSMDLK 80
>26711
Length = 405
Score = 55.1 bits (131), Expect = 1e-07, Method: Composition-based stats.
Identities = 39/111 (35%), Positives = 61/111 (54%), Gaps = 6/111 (5%)
Frame = -2
Query: 530 QLLRGVKHLHDNWILHRDLKTSNLLLSHAGI--LKVGDFGLAREYGSPLKAY----TPVV 583
Q+L ++H+H ++H DLK SNLLLS + +++ DFGLAR+ P + + TP
Sbjct: 392 QVLDILQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARKLYPPQETFLNHGTP-- 219
Query: 584 VTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINK 634
+ +PE L K STA D+W VG + LL+ + F +S + + K
Sbjct: 218 ---GFTSPE-ALDVKPISTASDVWGVGVLAYILLSGQSPFQADSATESLKK 78
>28157
Length = 400
Score = 55.1 bits (131), Expect = 1e-07, Method: Composition-based stats.
Identities = 44/129 (34%), Positives = 67/129 (51%), Gaps = 8/129 (6%)
Frame = +3
Query: 449 VALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSNMDK-IYIVMNYVEHD 507
VA+KR++ E+EK+ F ++E+ + + HPNIV + G+ D + +VM Y E
Sbjct: 9 VAVKRIESEQEKKSF----MQELKQLSRVSHPNIVCL----YGACRDHPVCLVMEYAEGG 164
Query: 508 --LKSLMETMKQP-FLPGEVKTLMIQLLRGVKHLHD---NWILHRDLKTSNLLLSHAGI- 560
L + QP + ++Q GV++LH ++HRDLK NLLL G
Sbjct: 165 SLYNVLHGSGPQPQYTAAHAMNWLLQCALGVEYLHGMKPKALIHRDLKPPNLLLIQCGTK 344
Query: 561 LKVGDFGLA 569
LK+ DFG A
Sbjct: 345 LKICDFGTA 371
>31489
Length = 329
Score = 54.7 bits (130), Expect = 2e-07, Method: Composition-based stats.
Identities = 28/81 (34%), Positives = 50/81 (61%), Gaps = 4/81 (4%)
Frame = +3
Query: 478 QHPNIVTVREIVVGSN----MDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLR 533
+H NI+++REI+ + I++V + +E DL ++ + QP ++ + Q+LR
Sbjct: 24 KHDNIISIREILKPKDSYHDFKDIHVVFDLMESDLHRIIYS-DQPLTEEHIRYFLYQILR 200
Query: 534 GVKHLHDNWILHRDLKTSNLL 554
G+K++H ++HRDLK SNLL
Sbjct: 201 GLKYIHSANVVHRDLKPSNLL 263
>17253
Length = 483
Score = 53.1 bits (126), Expect = 4e-07, Method: Composition-based stats.
Identities = 44/140 (31%), Positives = 67/140 (47%), Gaps = 14/140 (10%)
Frame = -1
Query: 457 EKEKEGFPITSLREINTILK-AQHPNIVTVREIVVGSNMDKIYIVMNYVEH-DLKSLMET 514
+ EK F LRE++ + K +HPN+V+ S D I+M + H DL S +
Sbjct: 426 DAEKSEF----LRELSIMRKLPRHPNVVSFMGCCTMS--DPALILMEFCCHGDLLSFLRK 265
Query: 515 MKQP----FLPGEVKTLM--------IQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILK 562
++P FL L + + RG+ H+ +N I+HRD+ N+L+S + K
Sbjct: 264 -RRPDRTVFLTSTANDLTARDFFSFALHVARGMAHVANNKIVHRDVAARNVLISERNVCK 88
Query: 563 VGDFGLAREYGSPLKAYTPV 582
V DFGL+R G Y V
Sbjct: 87 VSDFGLSRRVGDQNDVYEIV 28
>04852
Length = 1462
Score = 52.8 bits (125), Expect = 6e-07, Method: Compositional matrix adjust.
Identities = 30/90 (33%), Positives = 48/90 (53%)
Frame = +1
Query: 529 IQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWY 588
Q+ RG++ L +HRDL N+L++ +LK+ DFGL+R K + +W
Sbjct: 346 FQIARGMEFLASRKCIHRDLAARNVLVTEEHVLKIADFGLSRTGDYYKKRSGGRLPVKWM 525
Query: 589 RAPELLLGAKEYSTAVDMWSVGCIFGELLT 618
APE L + Y+T D+WS G + E+ +
Sbjct: 526 -APEALFDMR-YTTKSDVWSFGVVLWEIFS 609
>18401
Length = 463
Score = 51.6 bits (122), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 39/144 (27%), Positives = 66/144 (45%), Gaps = 14/144 (9%)
Frame = -3
Query: 579 YTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKE 638
++ +V T+ YRAPE++L +S D+WSVGCI EL T LF + + + + +
Sbjct: 461 HSTIVSTRHYRAPEVILELG-WSHPCDVWSVGCIMFELYTGYTLFQTHDNKEHLAMMERI 285
Query: 639 LGTPSEKI--------WPGYSELPVVKKMTFSEHPYNNLRKRFGALLS------DQGFDL 684
LG+ ++ + + L V ++ + + + N + + Q FDL
Sbjct: 284 LGSLPYRMAKKTKKQKYFHHGRLDVPERSSMARYVRENTKPLLRYVKDRENKDHQQLFDL 105
Query: 685 MNKFLTYFPGRRISAEDGLKHEYF 708
M K L Y R S L+H +F
Sbjct: 104 MKKLLAYEASSRYSLLQALQHPFF 33
>00715
Length = 1788
Score = 51.6 bits (122), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 48/177 (27%), Positives = 84/177 (47%), Gaps = 29/177 (16%)
Frame = +1
Query: 478 QHPNIVTVREIVVGSNM-----DKIYIVMNYV-EHDLKSLMETMKQPFLPGEVKTLMIQL 531
+H N+V++ +G+ D ++ M YV +L++++ +Q +L +Q+
Sbjct: 100 RHVNVVSI----LGATSLHRFEDGAWLAMEYVGPLNLQTILNDHQQDIDSSMRLSLALQM 267
Query: 532 LRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREY---------------GSPL 576
RG+ +LH I+H DLK +N LL+ L++ DFG + G+ L
Sbjct: 268 ARGLHYLHSINIVHLDLKPANCLLTRDLKLRIADFGCCHQLTPTGLDMGEREGGMAGNEL 447
Query: 577 KAYTPV--------VVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPG 625
+ TPV T YRAPELL G + S D++S+G ++ T++ + G
Sbjct: 448 E-LTPVQGAWKNELAGTLAYRAPELLKGLQP-SVRSDVYSLGITLWQMCTRQGPYEG 612
>21079
Length = 878
Score = 50.8 bits (120), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 34/91 (37%), Positives = 50/91 (54%), Gaps = 2/91 (2%)
Frame = +1
Query: 530 QLLRGVKHLHDNWILHRDLKTSNLLL--SHAGILKVGDFGLAREYGSPLKAYTPVVVTQW 587
Q+ GV ++H ILH DLK N+L ++ +K+ DFGLAR Y P + + T
Sbjct: 151 QICSGVGYMHTQSILHLDLKPENVLCVSDNSNQIKIIDFGLARFY-KPGDSLQVLFGTPE 327
Query: 588 YRAPELLLGAKEYSTAVDMWSVGCIFGELLT 618
+ APE ++ E + DMWS+G I LL+
Sbjct: 328 FIAPE-VVNYDEINFTTDMWSIGVICYILLS 417
>12672
Length = 773
Score = 50.8 bits (120), Expect = 2e-06, Method: Composition-based stats.
Identities = 31/89 (34%), Positives = 50/89 (56%), Gaps = 4/89 (4%)
Frame = +3
Query: 534 GVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREY----GSPLKAYTPVVVTQWYR 589
G+++L+DN +HRD+KT+N+LL KVGDF G ++ + V+ T Y
Sbjct: 27 GIQYLNDNGHVHRDIKTANILLDSEYTAKVGDFATVVSAPSGEGKTVQNASVVIGTAAYL 206
Query: 590 APELLLGAKEYSTAVDMWSVGCIFGELLT 618
APE + + ST +D +S G + E++T
Sbjct: 207 APEAI--HFDVSTKLDSYSFGVVLLEVIT 287
>16003
Length = 926
Score = 50.4 bits (119), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 35/99 (35%), Positives = 51/99 (51%)
Frame = -1
Query: 616 LLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKMTFSEHPYNNLRKRFGA 675
LL + P PG++++DQ+ K+F LGTP+E WP + LP + F L++ F A
Sbjct: 926 LLIRLPFLPGDTDLDQLGKIFNMLGTPTETEWPAVTSLP--DYIQFKHCQKQPLKEIFTA 753
Query: 676 LLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLP 714
D +L++K L P R +A LK YF P P
Sbjct: 752 -AGDDLLELLDKLLAMNPLHRCTATQALKMPYFSNKPYP 639
>00392
Length = 668
Score = 50.1 bits (118), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 46/163 (28%), Positives = 74/163 (45%), Gaps = 6/163 (3%)
Frame = +3
Query: 478 QHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTL---MIQLLRG 534
QHPNIV + N +++ E ++T + F VK L Q+L+G
Sbjct: 105 QHPNIVRFFDYWEEHNHRNRKVIILVTELMTSGTLKTYLKRFKKPNVKILKNWCRQVLKG 284
Query: 535 VKHLHDNW--ILHRDLKTSNLLLSH-AGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAP 591
+ LH ++HRDLK N+ ++ G +K+GD GLA V+ T + AP
Sbjct: 285 LYFLHTRTPPVIHRDLKCDNIFITGPTGSVKIGDLGLATLKNQSFAK--SVIGTPEFMAP 458
Query: 592 ELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINK 634
E+ + Y AVD+++ G E+ + + + S QI K
Sbjct: 459 EMY--EEHYDEAVDVYAFGMCMLEMASSEYPYSECSNAAQIYK 581
>12786
Length = 460
Score = 50.1 bits (118), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 38/117 (32%), Positives = 58/117 (49%), Gaps = 23/117 (19%)
Frame = -3
Query: 530 QLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLA----REYGSPLKAYTPVVVT 585
++LR VK LH+ ++H DLK +N +L AG LK+ DFG+A ++ S LK V T
Sbjct: 386 EMLRAVKALHNEGVIHSDLKPANFMLV-AGNLKLIDFGIANTLQQDKTSVLK--DSRVGT 216
Query: 586 QWYRAPELLLGAKE-----------------YSTAV--DMWSVGCIFGELLTQKPLF 623
Y +PE ++ A + Y V D+WS+GCI ++ + F
Sbjct: 215 PSYMSPEAIMAACDDSADDSMEEDGHRTKPKYKVGVRSDVWSLGCILYNMVYGRTPF 45
>17300
Length = 480
Score = 49.3 bits (116), Expect = 5e-06, Method: Composition-based stats.
Identities = 31/90 (34%), Positives = 51/90 (56%), Gaps = 5/90 (5%)
Frame = +1
Query: 534 GVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLK--AYTP---VVVTQWY 588
G+ L D +HRDL N+L++ + KV DFGL+RE S AYT + +W
Sbjct: 10 GMGXLADMGYVHRDLAARNILVNEILVCKVADFGLSREIESDTTEGAYTTKGGKIPVRW- 186
Query: 589 RAPELLLGAKEYSTAVDMWSVGCIFGELLT 618
APE + +++++A D+WS G + E+++
Sbjct: 187 TAPE-AIAYRKFTSASDVWSFGVVMWEVMS 273
>31885
Length = 529
Score = 47.4 bits (111), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 46/161 (28%), Positives = 73/161 (45%), Gaps = 4/161 (2%)
Frame = -2
Query: 471 INTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQ 530
++ + + HP +V + D +V ++ DL+ M+ + F VK + Q
Sbjct: 519 VDMLTRLDHPFLVNLW-YAFQDEEDLFMVVDLFLGGDLRYHMQQ-EVSFREDCVKFYLCQ 346
Query: 531 LLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRA 590
L + +L I+HRD+K N+LL G V DF +A + A T T+ Y A
Sbjct: 345 LALVLDYLRSQKIVHRDIKPDNILLDEQGHCHVTDFNIATQLEDDELA-TSTSGTRPYMA 169
Query: 591 PELLLGA----KEYSTAVDMWSVGCIFGELLTQKPLFPGNS 627
PE+ A + Y VD WS+G ELL ++ F +S
Sbjct: 168 PEVYGVAINERRGYGFPVDWWSLGVSLFELLKKRRPFSVHS 46
>11780
Length = 1713
Score = 45.8 bits (107), Expect = 7e-05, Method: Compositional matrix adjust.
Identities = 51/202 (25%), Positives = 98/202 (48%), Gaps = 4/202 (1%)
Frame = +3
Query: 429 IEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREI 488
I +G +G VY+ + + VA+K+LK +K+ + L+E + + +H N+V + +
Sbjct: 621 IGKGDFGDVYKGMYR--GQPVAIKQLK---DKDRGEQSFLQEASVMTSLRHDNLVRLIGV 785
Query: 489 VVGSNMDKIYIVMNYV-EHDLKSLMETMKQPFLPGEVK-TLMIQLLRGVKHLHDNWILHR 546
V+G + I++V ++ + +L + + + + + + +++L ++HR
Sbjct: 786 VLG---ETIFLVTEFMGKGNLVEYLRSRGRSVITKKDQINFATDTCAAMEYLESKRLVHR 956
Query: 547 DLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEY--STAV 604
DL N+L+ G KV DFGLA+ +G + T V + APE L K + V
Sbjct: 957 DLAARNVLVHDDGKAKVSDFGLAK-FGDF--SQTSVKFPIKWTAPEALRENKIH*QVRHV 1127
Query: 605 DMWSVGCIFGELLTQKPLFPGN 626
++W + + G LL P N
Sbjct: 1128ELWHI--VMGNLLLWSSALP*N 1187
>05084
Length = 1324
Score = 45.1 bits (105), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 28/92 (30%), Positives = 43/92 (46%), Gaps = 4/92 (4%)
Frame = +2
Query: 623 FPGNSEIDQINKVFKELGTPS----EKIWPGYSELPVVKKMTFSEHPYNNLRKRFGALLS 678
PG+S +DQ+ ++ K LGTP+ ++ P YSE K HP+ K F
Sbjct: 2 LPGDSGVDQLVEIIKVLGTPTREQIREMNPNYSEF---KFPQIKAHPWT---KVFRPRTP 163
Query: 679 DQGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 710
+ L+++ L Y P RI + H +F E
Sbjct: 164 PEAIQLVSRLLEYTPSARIQPMEACAHAFFDE 259
>20640
Length = 1492
Score = 44.3 bits (103), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 26/79 (32%), Positives = 40/79 (50%), Gaps = 4/79 (5%)
Frame = +1
Query: 544 LHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYT----PVVVTQWYRAPELLLGAKE 599
+HRDL T N L+ H ++K+ DFGLAR S + Y + +W +L +
Sbjct: 10 VHRDLATRNCLVGHDLVVKISDFGLARSVHS-VDYYRGSEHDAIPIRWMPLEAILYN--K 180
Query: 600 YSTAVDMWSVGCIFGELLT 618
+ST D+WS G + E+
Sbjct: 181 FSTQSDVWSFGVVLWEIFA 237
>07836
Length = 1478
Score = 43.5 bits (101), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 53/190 (27%), Positives = 85/190 (44%), Gaps = 20/190 (10%)
Frame = -1
Query: 447 EIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIV--TVREIVVGSNMDKIYIVMNYV 504
E VA+K +E F T L + T+L +H NI+ +I + +++++ +Y
Sbjct: 1475 ENVAVKIFFTTEEASWFRETELYQ--TVL-LRHENILGFIAADIKGTGSWTQLFLITDY- 1308
Query: 505 EHDLKSLMETMKQPFL-PGEVKTLMIQLLRGVKHLHDNW--------ILHRDLKTSNLLL 555
H+ SL + + L E+ L + G+ HLH I HRD+K+ N+L+
Sbjct: 1307 -HENGSLHDYLLSRVLDSSEMLALAHSAICGLAHLHIEIFGTRGKPAIAHRDIKSKNILV 1131
Query: 556 SHAGILKVGDFGLAREYGSPLK----AYTPVVVTQWYRAP---ELLLGAKEYST--AVDM 606
G + D GLA Y S A P T+ Y AP E+LL K + DM
Sbjct: 1130 KKNGTCCIADLGLAVRYISESNEVDVAPNPRQGTKRYMAPEVLEMLLNVKNFDAFKQADM 951
Query: 607 WSVGCIFGEL 616
++ G + E+
Sbjct: 950 YAFGLVMWEI 921
>17975
Length = 449
Score = 43.5 bits (101), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 35/146 (23%), Positives = 67/146 (45%), Gaps = 10/146 (6%)
Frame = +3
Query: 434 YGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSN 493
+ VV A+ T E VA+K + K E +E+ + QHPN+V + E++
Sbjct: 6 FAVVKLARHVFTGEKVAVKVIDKTKLDEVSRSHLFQEVRCMKLVQHPNVVRLYEVI--DT 179
Query: 494 MDKIYIVM---------NYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWIL 544
K+Y+++ +Y+ L E + + + Q++ + + H ++
Sbjct: 180 QTKLYLILELGDGGDMYDYIMRHSGGLEEKLAKRYFR--------QIVEAISYCHKLHVV 335
Query: 545 HRDLKTSNLLLSHA-GILKVGDFGLA 569
HRDLK N++ G++K+ DFG +
Sbjct: 336 HRDLKPENVVFFEKPGLVKLTDFGFS 413
>21433
Length = 590
Score = 42.0 bits (97), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 33/94 (35%), Positives = 50/94 (53%)
Frame = +2
Query: 528 MIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQW 587
+ QL +++ H ++HRD+K NLLL G LK+ DFG + +P T + T
Sbjct: 185 IYQLSSALEYCHYRKVIHRDIKPENLLLGLKGDLKIADFGWSVH--APSSRRTTMCGTLD 358
Query: 588 YRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKP 621
Y PE++ G K + VD+WS+G + E L P
Sbjct: 359 YLPPEMVEG-KTHDENVDLWSLGVLCYEFLVGTP 457
>07291
Length = 833
Score = 41.6 bits (96), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 28/96 (29%), Positives = 50/96 (52%), Gaps = 6/96 (6%)
Frame = +1
Query: 530 QLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGS--PLKAYT----PVV 583
Q+ G+ +L + ++HR+L N +++ G L++ D+G+ GS P YT P
Sbjct: 73 QIADGMAYLQEVKVVHRNLAARNCIVTEDGRLQLSDYGVT---GSLFPQSYYTADDSPAR 243
Query: 584 VTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQ 619
+ APE + +S+ D+W+ G + ELLT+
Sbjct: 244 DLVKWMAPE-TIDNFHFSSKSDVWAFGVVLWELLTR 348
>15549
Length = 470
Score = 40.4 bits (93), Expect = 0.003, Method: Composition-based stats.
Identities = 18/54 (33%), Positives = 35/54 (64%), Gaps = 1/54 (1%)
Frame = -1
Query: 407 LPKYLPALQ-GCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKE 459
LP P+ + R +EF+C+ ++ +G YG+V+RAK+K ++ A+KR+ + +
Sbjct: 263 LPDKAPSAEFKSRFADEFECIEQMGKGGYGIVFRAKNKVDEQEYAVKRIALPSD 102
>02638
Length = 1490
Score = 39.3 bits (90), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 18/50 (36%), Positives = 30/50 (60%)
Frame = +1
Query: 588 YRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFK 637
+ APE+L G + Y A D+WSVGC+ E+ T +P + + + + +FK
Sbjct: 34 FMAPEVLRG-ESYGRACDVWSVGCVMIEMCTCRPPWNSHDISNHLALIFK 180
>14477
Length = 493
Score = 38.9 bits (89), Expect = 0.008, Method: Compositional matrix adjust.
Identities = 41/147 (27%), Positives = 70/147 (47%), Gaps = 4/147 (2%)
Frame = -1
Query: 428 RIEEGTYGVVYRAKDKKTD-EI-VALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTV 485
++ G +G V + + D EI VA+K LK ++E + K H +IV +
Sbjct: 469 KLGAGNFGSVMKGVCRLDDREIPVAIKVLKNADLDPSVQSELIKEAEVMKKMDHMHIVRL 290
Query: 486 REIVVGSNMDKIYIVMNYVEHDLKSLMETM-KQPFLP-GEVKTLMIQLLRGVKHLHDNWI 543
+ G M +V+ + L L + + K LP + LM Q+ +G+++L N
Sbjct: 289 IGLCEGETM---MLVLELAK--LGPLNKFLPKNKHLPLWNILELMWQVSQGMEYLEANKF 125
Query: 544 LHRDLKTSNLLLSHAGILKVGDFGLAR 570
+HRDL N+LL K+ DFG+++
Sbjct: 124 VHRDLAARNILLCDEHFAKISDFGMSK 44
>26009
Length = 886
Score = 32.0 bits (71), Expect(2) = 0.008, Method: Compositional matrix adjust.
Identities = 12/33 (36%), Positives = 22/33 (66%)
Frame = +3
Query: 523 EVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLL 555
E K++M QL+ + +H ++HRD+K N+L+
Sbjct: 714 EAKSVMKQLVSALDFMHSKQLVHRDIKPENVLI 812
Score = 25.8 bits (55), Expect(2) = 0.008, Method: Compositional matrix adjust.
Identities = 23/93 (24%), Positives = 35/93 (37%), Gaps = 5/93 (5%)
Frame = +2
Query: 421 EEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREIN-----TIL 475
E + + GTYG V A+ + T VALK L T LRE +
Sbjct: 416 EHYDVCKELGRGTYGKVVLARCRHTGTQVALKLLPKS-------CTKLREFQREFQLSYF 574
Query: 476 KAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDL 508
+ H NI+ + + ++ + V DL
Sbjct: 575 LSPHANIIDTYNVAFQTRSSYVFAQEHAVLGDL 673
>37602
Length = 804
Score = 38.9 bits (89), Expect = 0.008, Method: Compositional matrix adjust.
Identities = 20/72 (27%), Positives = 39/72 (54%)
Frame = -1
Query: 495 DKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLL 554
+K++I M Y + + P ++ + + L+G+ +LH +HRD+K +N+L
Sbjct: 300 EKLWIAMEYCGGGSMQDIYHVTGPLTEPQIAFVCRETLKGLHYLHRRGKMHRDIKGANIL 121
Query: 555 LSHAGILKVGDF 566
L+ G +K+ DF
Sbjct: 120 LTEEGDVKLADF 85
Score = 28.9 bits (63), Expect = 9.3, Method: Compositional matrix adjust.
Identities = 13/36 (36%), Positives = 21/36 (58%)
Frame = -2
Query: 406 ELPKYLPALQGCRSVEEFQCLNRIEEGTYGVVYRAK 441
E K +Q +++F+ + R+ GTYG VY+AK
Sbjct: 554 EYKKMQADIQRRNPLDDFELIQRVGSGTYGDVYKAK 447
>16708
Length = 1397
Score = 38.9 bits (89), Expect = 0.009, Method: Compositional matrix adjust.
Identities = 16/52 (30%), Positives = 31/52 (59%)
Frame = -1
Query: 521 PGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREY 572
P V + Q + ++H+H+ ++H D+K N+L+ G K+ D+G+A+ Y
Sbjct: 1097 PAMVCCIAGQXVCALEHIHELGVVHMDVKADNVLVDAHGNCKLTDYGIAQLY 942
>18481
Length = 437
Score = 38.1 bits (87), Expect = 0.014, Method: Compositional matrix adjust.
Identities = 24/77 (31%), Positives = 38/77 (49%), Gaps = 3/77 (3%)
Frame = -1
Query: 499 IVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLS-- 556
+VM + L+ L K+ F + + QLL ++ +H +HRDLK N L+
Sbjct: 266 LVMELLGPSLEELFVICKRRFTLKTILMVSDQLLSRLEFIHQKCFIHRDLKPDNFLMGLG 87
Query: 557 -HAGILKVGDFGLAREY 572
H L + DFGL++ Y
Sbjct: 86 RHCHRLYIIDFGLSKRY 36
>13078
Length = 773
Score = 38.1 bits (87), Expect = 0.015, Method: Compositional matrix adjust.
Identities = 31/125 (24%), Positives = 59/125 (47%), Gaps = 14/125 (11%)
Frame = -1
Query: 600 YSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKI--------WPGYS 651
+S D+WS+GCI EL T LF + + + + + LG+ ++ + +
Sbjct: 746 WSQPCDVWSIGCIMFELYTGYTLFQTHDNKEHLAMMERILGSLPYRMAKKTKKQKYFYHG 567
Query: 652 ELPVVKKMTFSEHPYNNLR--KRFGALLSD----QGFDLMNKFLTYFPGRRISAEDGLKH 705
L +K + + +N++ +R+ + Q FDLM+K L+Y R S ++H
Sbjct: 566 RLDWDEKSSAGRYVRDNVKPLRRYVKDPDNEDHQQLFDLMDKMLSYEVSTRYSLRQAMRH 387
Query: 706 EYFRE 710
+FR+
Sbjct: 386 PFFRK 372
>00486
Length = 797
Score = 35.4 bits (80), Expect = 0.090, Method: Compositional matrix adjust.
Identities = 18/50 (36%), Positives = 27/50 (54%)
Frame = -2
Query: 588 YRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFK 637
Y APE+L + AVD WS+G + ++LT P F + I+K+ K
Sbjct: 760 YMAPEILTRTG-HGKAVDWWSLGALMYDMLTGSPPFTAENRKKTIDKILK 614
>36481
Length = 806
Score = 33.1 bits (74), Expect = 0.42, Method: Compositional matrix adjust.
Identities = 37/149 (24%), Positives = 66/149 (44%), Gaps = 6/149 (4%)
Frame = +2
Query: 413 ALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLK-MEKEKEGFPITSLREI 471
++G S + + EGT+G V + KD + +ALK +K ++K +E + EI
Sbjct: 338 TMRGTSSTNDMKLCPHWGEGTFGKVVQCKDLLKGDDIALKIIKNVDKYREAAKL----EI 505
Query: 472 NTILKAQ----HPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGE-VKT 526
N + K + H + V+ + + I + + + ++ P E V+
Sbjct: 506 NVLEKLREKDPHAKHMCVQMLDWFDYHGHVCISFHMLGLSVFDFLKDNSYGAYPIEQVRH 685
Query: 527 LMIQLLRGVKHLHDNWILHRDLKTSNLLL 555
+ QL V LH+N + H DLK N+L
Sbjct: 686 ISYQLCYAVNFLHENQLTHTDLKPENILF 772
>15931
Length = 447
Score = 30.4 bits (67), Expect = 2.6, Method: Compositional matrix adjust.
Identities = 13/31 (41%), Positives = 19/31 (61%)
Frame = +1
Query: 680 QGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 710
Q FDLM+K L+Y R S ++H +FR+
Sbjct: 70 QLFDLMDKMLSYEVSTRYSLRQAMRHPFFRK 162
>00145
Length = 2325
Score = 30.4 bits (67), Expect = 3.0, Method: Composition-based stats.
Identities = 18/46 (39%), Positives = 24/46 (52%), Gaps = 1/46 (2%)
Frame = -1
Query: 693 PGRRISAEDGLKHEYFRETP-LPIDPSMFPTWPAKSEQQRVKRGTS 737
P RIS DG + RE+P LP D + P P + Q+ V R T+
Sbjct: 2313 PQHRISQSDGESVDVQRESPLLPRDGAAVPQRPGPAAQEGVSRQTA 2176
>20152
Length = 445
Score = 30.0 bits (66), Expect = 3.9, Method: Compositional matrix adjust.
Identities = 14/33 (42%), Positives = 20/33 (60%)
Frame = +1
Query: 591 PELLLGAKEYSTAVDMWSVGCIFGELLTQKPLF 623
PE+LLG + AVD+WS+G I L+ + F
Sbjct: 1 PEILLGDSYDAPAVDVWSLGVILYMLVVGEAPF 99
>38560
Length = 479
Score = 29.3 bits (64), Expect = 6.5, Method: Composition-based stats.
Identities = 12/30 (40%), Positives = 18/30 (60%)
Frame = -3
Query: 588 YRAPELLLGAKEYSTAVDMWSVGCIFGELL 617
Y APEL+ G + + D+WS+G + LL
Sbjct: 387 YAAPELISGLEYLGSEADIWSMGVLLYALL 298
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000350403 | hsapiens_gene_ensembl | PITSLRE
serine/threonine-protein kinase CDC2L2 (EC 2.7.11.22)
(Galactosyltransferase-associated protein kinase p58/GTA) (Cell
division cycle 2-like protein kinase 2) (CDK11).
[Source:Uniprot/SWISSPROT;Acc:Q9UQ88]
(779 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
29581 292 4e-84
01060 228 6e-60
01756 222 5e-58
14126 219 3e-57
04591 194 9e-50
32000 170 3e-42
01707 162 4e-40
04138 150 1e-36
01966 118 3e-28
23319 103 4e-22
00300 95 1e-19
03294 87 2e-17
18921 86 8e-17
06405 83 4e-16
13592 82 6e-16
12721 82 1e-15
01718 80 4e-15
09606 78 2e-14
03508 77 4e-14
20559 66 1e-13
12453 74 2e-13
14420 73 4e-13
15910 71 1e-12
26560 68 1e-11
19761 65 8e-11
18484 65 9e-11
21578 64 2e-10
27546 63 5e-10
03240 62 1e-09
14116 62 1e-09
30755 61 1e-09
13066 61 2e-09
13212 61 2e-09
28638 61 2e-09
26909 60 4e-09
19094 59 8e-09
21808 58 1e-08
11185 57 3e-08
28157 56 6e-08
27405 56 6e-08
19301 56 6e-08
18287 56 7e-08
24241 55 9e-08
26711 55 9e-08
07940 55 1e-07
31489 55 1e-07
17253 53 4e-07
04852 52 7e-07
18401 52 1e-06
00715 52 1e-06
12672 51 2e-06
21079 51 2e-06
16003 50 2e-06
00392 50 3e-06
12786 50 4e-06
17300 49 6e-06
31885 47 2e-05
11780 46 7e-05
05084 45 1e-04
20640 44 2e-04
07836 44 3e-04
17975 44 4e-04
21433 42 0.001
07291 42 0.001
15549 40 0.005
02638 39 0.005
18481 39 0.006
26009 32 0.006
14477 39 0.007
16708 39 0.008
37602 39 0.008
13078 38 0.019
00486 35 0.090
36481 33 0.31
00145 30 2.6
15931 30 2.7
38560 29 6.5
>29581
Length = 1278
Score = 292 bits (747), Expect(2) = 4e-84, Method: Compositional matrix adjust.
Identities = 133/261 (50%), Positives = 183/261 (70%)
Frame = -2
Query: 473 ILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLR 532
+L +H NIV ++E+VVG ++D +++VM Y E DL SL++ M PF +VK +++QLL+
Sbjct: 1193 LLNLRHQNIVQLQEVVVGKSLDSLFLVMEYCEQDLASLLDNMPAPFSESQVKCIVLQLLK 1014
Query: 533 GVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPEL 592
G+++LH+ +I+HRDLK SNLL++ G +K+ DFGLAR YG P K TP VVT WYRAPEL
Sbjct: 1013 GLRYLHEAFIIHRDLKVSNLLMTDKGCVKIADFGLARNYGKPQKPMTPKVVTLWYRAPEL 834
Query: 593 LLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSEL 652
L G+K +STA+DMWS GCI GELL KPL PG S++ QI + + LGTP++ IWPG+S+L
Sbjct: 833 LFGSKTHSTAIDMWSAGCILGELLGHKPLMPGRSDLQQIELIMELLGTPNDTIWPGFSQL 654
Query: 653 PVVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPL 712
P ++ T + PYNNLR F LS+ G L+N Y P +R +AED L+H YF+E P
Sbjct: 653 PAFEQFTLKKQPYNNLRHTF-PWLSESGIRLLNGLFMYHPQKRATAEDCLEHSYFKEQPY 477
Query: 713 PIDPSMFPTWPAKSEQQRVKR 733
P DP P++P Q R+KR
Sbjct: 476 PCDPEFMPSFP----QHRLKR 426
Score = 38.9 bits (89), Expect(2) = 4e-84, Method: Composition-based stats.
Identities = 17/35 (48%), Positives = 25/35 (71%)
Frame = -1
Query: 445 DEIVALKRLKMEKEKEGFPITSLREINTILKAQHP 479
+EIVALK+++M E+ G PI+ LREIN ++ P
Sbjct: 1278 NEIVALKKMRMTGERYGIPISGLREINIFAQSATP 1174
>01060
Length = 1800
Score = 228 bits (582), Expect = 6e-60, Method: Compositional matrix adjust.
Identities = 122/338 (36%), Positives = 204/338 (60%), Gaps = 2/338 (0%)
Frame = +1
Query: 397 LLPIELKQELPKYLPALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKME 456
LL + +K+ + + AL + +FQ +I EGTYGVVY+ + + T +A+K++++
Sbjct: 22 LLKLNIKRLMMDFETALS---DLTDFQ---KIGEGTYGVVYKCRHRATGRKLAMKKIRLR 183
Query: 457 KEKEGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQ 516
++G P +++REI + + +H NIV + ++++ +++++V ++ DLK ++ +
Sbjct: 184 GSEDGVPSSAIREIAMLRELRHTNIVCLEDVIMED--ERLFLVFEFLSMDLKMYIDKFPE 357
Query: 517 PFLPGE--VKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSP 574
+ VK+ + Q++ G+ H I+HRDLK NLL++H G +K+ DFG+AR + P
Sbjct: 358 GVVLDRRLVKSYVFQIVTGIXFCHQRRIVHRDLKPQNLLINHTGAIKIADFGMARTFALP 537
Query: 575 LKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKV 634
++AYT VVT WYRAPE+L+GA +YST VD+WS+G IF ++L + P+F G+SEIDQ+ K+
Sbjct: 538 VRAYTHEVVTLWYRAPEILMGASKYSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKI 717
Query: 635 FKELGTPSEKIWPGYSELPVVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGR 694
F+ +GTP+E+ WP + +LP M F L + L S G DL+ + L P +
Sbjct: 718 FRIIGTPTEQTWPEFHKLPAFNGM-FPLWKEGKLSETLTDLDS-LGLDLIERTLKCDPAQ 891
Query: 695 RISAEDGLKHEYFRETPLPIDPSMFPTWPAKSEQQRVK 732
RIS + L+H YF + P P+ P S R+K
Sbjct: 892 RISCKKMLQHAYFLNVDTSVKPVDVPS-PEHS*STRLK 1002
>01756
Length = 1858
Score = 222 bits (565), Expect = 5e-58, Method: Compositional matrix adjust.
Identities = 117/309 (37%), Positives = 187/309 (60%), Gaps = 10/309 (3%)
Frame = -3
Query: 416 CRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILK 475
C +++ L +I +GT+G V++A+ KKT ++VA+K++ M+ EKEGFPIT+LREI +
Sbjct: 1754 CDEDAKYEKLAKIGQGTFGEVFKARCKKTKQVVAMKKVLMDNEKEGFPITALREIKILQL 1575
Query: 476 AQHPNIVTVREIV----VGSNMDK--IYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQ 529
H N+V + EI +N K Y+V + EHDL L+ M F E+K +M Q
Sbjct: 1574 LNHENVVDLIEICSTKATSANRYKSMFYLVFEFCEHDLAGLLSNMSVVFNLPEIKEVMKQ 1395
Query: 530 LLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKA---YTPVVVTQW 586
L+ G+ ++H N ILHRD+K +N+L++ G+LK+ DFGLAR + L+ YT VVT W
Sbjct: 1394 LMNGLYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLW 1215
Query: 587 YRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIW 646
YR PELLLG + YSTA+D W GCI E+ T+ P+ G +E +Q+ + + G+ + ++W
Sbjct: 1214 YRPPELLLGDRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQNQLTLITQLCGSITPEVW 1035
Query: 647 PGYSELPVVKKMTFSEHPYNNLRKRFGALLSDQ-GFDLMNKFLTYFPGRRISAEDGLKHE 705
PG L + + + +++R + D DL++K L PG+R+++++ L H+
Sbjct: 1034 PGVERLELYNSLDLPQGNKRKVKERLRYYIKDAYALDLLDKLLALDPGKRVNSDEALSHD 855
Query: 706 YFRETPLPI 714
+F P P+
Sbjct: 854 FFWMDPEPL 828
>14126
Length = 1265
Score = 219 bits (558), Expect = 3e-57, Method: Compositional matrix adjust.
Identities = 125/299 (41%), Positives = 182/299 (60%), Gaps = 9/299 (3%)
Frame = +3
Query: 420 EEFQCLNRIEEGTYGVVYRAKD-KKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQ- 477
++++ + I G YG VY+A+D + E VA+KR+++ +EG P+ ++REI+ + + +
Sbjct: 189 QKYEEVAVIGNGAYGTVYKARDLRNQGEFVAMKRIRLNNTEEGMPMMAIREISMLKQLEQ 368
Query: 478 --HPNIVTVREIVVGSNMDK---IYIVMNYVEHDLKSLMETMKQPFL-PGEVKTLMIQLL 531
HPN+V + ++ + D+ + +V Y+EHDL + + P L P +K LM+QLL
Sbjct: 369 YEHPNVVRLLDVSHNTITDREIRLNLVFEYIEHDLATYLAKCPSPGLGPDRIKDLMLQLL 548
Query: 532 RGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPE 591
GV LH N I+HRDLK NLL+S G LK+ DFGLAR Y + A T VVVT WYR+PE
Sbjct: 549 NGVDFLHSNRIVHRDLKPQNLLISKDGRLKLADFGLARIYSFHM-ALTTVVVTLWYRSPE 725
Query: 592 LLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWP-GYS 650
+L+ A EY T+VD+WS GCIF EL T++ LF G+SE DQ+ K+F+ +G P WP G S
Sbjct: 726 VLMQA-EYGTSVDIWSCGCIFAELFTRRALFKGSSEFDQLKKIFEVIGLPPAGDWPEGVS 902
Query: 651 ELPVVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 709
V + +F P L+ + Q DLM K L + GRRIS+ + L H Y R+
Sbjct: 903 ----VHRNSFRPTPPVPLQTLVPE-MDPQAKDLMEKMLVFKSGRRISSRESLLHPYLRD 1064
>04591
Length = 1117
Score = 194 bits (494), Expect = 9e-50, Method: Compositional matrix adjust.
Identities = 102/267 (38%), Positives = 161/267 (60%), Gaps = 7/267 (2%)
Frame = -2
Query: 459 KEGFPITSLREINTILKAQHPNIVTVREIV------VGSNMDKIYIVMNYVEHDLKSLME 512
KEGFPIT+LREI + + +H N+V ++EI Y++ Y ++DL L+
Sbjct: 1101 KEGFPITALREIKILQQLEHENVVQLQEICHTQAGPYNRYKSTFYLIFEYCDYDLAGLLN 922
Query: 513 TMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYG 572
++ F + K LM QLL G+ ++H ILHRD+K +N+LL+ G+LK+ DFGL+R +
Sbjct: 921 NLRVKFSLADKKNLMSQLLNGLFYIHTKQILHRDIKAANILLTRDGVLKLADFGLSRPWV 742
Query: 573 SPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQIN 632
K T VVT WYR PELLLG +EY +DMW VGCI E+ ++KPL G SE Q++
Sbjct: 741 KS-KRLTNRVVTLWYRPPELLLGEREYGPEIDMWGVGCIMAEMWSRKPLMQGRSEQHQLS 565
Query: 633 KVFKELGTPSEKIWPGYSELPVVKKMTFSEHPYNNLRKRFGALLSD-QGFDLMNKFLTYF 691
+ G+ + ++WPG ++L + K+ + +++R LL + +G +L++ FL
Sbjct: 564 LITDLCGSLNAEVWPGVTKLELYGKLDLPQGKPRKVKERMLDLLKNKEGAELIDIFLRLD 385
Query: 692 PGRRISAEDGLKHEYFRETPLPIDPSM 718
PG+R++ ++ L H++F PLP PS+
Sbjct: 384 PGQRMNCDNALSHDFFWVDPLP-SPSL 307
>32000
Length = 644
Score = 170 bits (430), Expect = 3e-42, Method: Compositional matrix adjust.
Identities = 79/150 (52%), Positives = 106/150 (70%)
Frame = -1
Query: 560 LKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQK 619
+K+ DFGLAR +G P++ YT V+T WYRAPE+LLG + YS VD+WS+GCIF E++T++
Sbjct: 572 MKIADFGLARVFGLPVRTYTHEVITLWYRAPEILLGCRFYSVPVDIWSLGCIFVEMMTRR 393
Query: 620 PLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKMTFSEHPYNNLRKRFGALLSDQ 679
LFPG+SEIDQ+ ++F+ LGTP EK+WPG S+LP K TF + P NL LS
Sbjct: 392 ALFPGDSEIDQLYRIFRTLGTPDEKVWPGVSKLPDYKP-TFPKWPLKNLETVVS--LSKV 222
Query: 680 GFDLMNKFLTYFPGRRISAEDGLKHEYFRE 709
G DL+ + LTY P RRISA ++H YF +
Sbjct: 221 GLDLLKRMLTYNPNRRISARSAMRHPYFND 132
>01707
Length = 757
Score = 162 bits (410), Expect = 4e-40, Method: Compositional matrix adjust.
Identities = 81/221 (36%), Positives = 138/221 (62%)
Frame = +1
Query: 419 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 478
+E+++ + +I EG+YGVV++ ++K+T ++VA+K+ ++ ++REI + + +H
Sbjct: 61 MEKYEKIGKIGEGSYGVVFKCRNKETSQLVAIKKFVESEDDPLIKKIAMREIRMLKQLKH 240
Query: 479 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLH 538
PN+V R I V ++++V +YV+H L + ++ + VK ++ Q L V H
Sbjct: 241 PNLV--RLIEVFRRKKRLHLVFDYVDHTLLNELDRYPRGLPEPMVKRIIYQTLLAVNFCH 414
Query: 539 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKE 598
+HRD+K N+L++ G +K+ DFG AR P YT V T+WYRAPELL+G +
Sbjct: 415 QYNTIHRDVKPENILITRQGQVKLCDFGFARILTGPGDEYTDYVATRWYRAPELLVGDTQ 594
Query: 599 YSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELG 639
Y VD+W++GC+F ELLT + L+PG S++DQ++ + K LG
Sbjct: 595 YGPPVDVWAIGCVFAELLTGQALWPGRSDVDQLHLIRKTLG 717
>04138
Length = 800
Score = 150 bits (380), Expect = 1e-36, Method: Compositional matrix adjust.
Identities = 72/178 (40%), Positives = 111/178 (62%), Gaps = 6/178 (3%)
Frame = +1
Query: 536 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKA---YTPVVVTQWYRAPEL 592
++H N ILHRD+K +N+L++ G+LK+ DFGLAR + L+ YT VVT WYR PEL
Sbjct: 58 YIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRPPEL 237
Query: 593 LLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSEL 652
LLG + YSTA+D W GCI E+ T+ P+ G +E +Q+ + + G+ + ++WPG ++L
Sbjct: 238 LLGDRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQNQLTLITQLCGSITPEVWPGVTQL 417
Query: 653 PVVKKM--TFSEHPYNNLRKRFGALLSD-QGFDLMNKFLTYFPGRRISAEDGLKHEYF 707
+ ++ + N +R RF +L D G DL + L P +RISA++ L H++F
Sbjct: 418 SMYHQIKGALAAGRKNIIRDRFARILKDPYGLDLFERLLKMDPSQRISADEALNHDFF 591
>01966
Length = 1735
Score = 118 bits (296), Expect(2) = 3e-28, Method: Compositional matrix adjust.
Identities = 55/175 (31%), Positives = 107/175 (61%), Gaps = 2/175 (1%)
Frame = -1
Query: 439 AKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYI 498
+ + T +A+K++++ ++G P +++REI + + +H NIV + ++++ +++++
Sbjct: 1654 CRHRATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTNIVCLEDVIMED--ERLFL 1481
Query: 499 VMNYVEHDLKSLMETMKQPFLPGE--VKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSH 556
V ++ DLK ++ + + VK+ + Q++ G+ H I+HRDLK NLL++H
Sbjct: 1480 VFEFLSMDLKMYIDKFPEGVVLDRRLVKSYVFQIVTGINFCHQRRIVHRDLKPQNLLINH 1301
Query: 557 AGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCI 611
G +K+ DFG+AR + P++AYT VVT WYRAPE+L+G + + W+ G +
Sbjct: 1300 TGAIKIADFGMARTFALPVRAYTHEVVTLWYRAPEILMGPQ---STPPXWTCGAL 1145
Score = 25.4 bits (54), Expect(2) = 3e-28, Method: Composition-based stats.
Identities = 10/13 (76%), Positives = 12/13 (92%)
Frame = -2
Query: 425 LNRIEEGTYGVVY 437
L++I EGTYGVVY
Sbjct: 1695 LSKIGEGTYGVVY 1657
Score = 97.4 bits (241), Expect = 2e-20, Method: Compositional matrix adjust.
Identities = 54/138 (39%), Positives = 80/138 (57%)
Frame = -3
Query: 595 GAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPV 654
GA +YST VD+WS+G IF ++L + P+F G+SEIDQ+ K+F+ +GTP+E+ WP + +LP
Sbjct: 1187 GASKYSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKLPA 1008
Query: 655 VKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPI 714
M F L + L S G DL+ + L P +RIS + L+H YF +
Sbjct: 1007 FNGM-FPLWKEGKLSETLTDLDS-LGLDLIERTLKCDPAQRISCKKMLQHAYFLNVDTSV 834
Query: 715 DPSMFPTWPAKSEQQRVK 732
P P+ P +S R+K
Sbjct: 833 KPVDVPS-PEQS*STRLK 783
>23319
Length = 2235
Score = 103 bits (256), Expect = 4e-22, Method: Compositional matrix adjust.
Identities = 50/117 (42%), Positives = 72/117 (61%), Gaps = 1/117 (0%)
Frame = +3
Query: 596 AKEYSTAVDMWSVGCIFGELLTQ-KPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPV 654
AK YST++DMWS GCIF EL +PLFPGN + DQ+ ++FK LGTP+E WPG ++LP
Sbjct: 18 AKMYSTSIDMWSAGCIFAELANAGRPLFPGNDDDDQLKRIFKLLGTPTEDQWPGMTQLPN 197
Query: 655 VKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETP 711
+ F + ++ L+ +G DL+ L P R+SA++ L+H YF + P
Sbjct: 198 YR--MFPMYHVTTTWQQVVPKLNSKGRDLLQCLLVCCPSDRMSADEALQHPYFADLP 362
>00300
Length = 2318
Score = 95.1 bits (235), Expect = 1e-19, Method: Compositional matrix adjust.
Identities = 66/207 (31%), Positives = 108/207 (52%), Gaps = 13/207 (6%)
Frame = -1
Query: 426 NRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKA----QHPNI 481
N+I EG +G VY A + T E++ALK +K + + LRE+ +K QH N+
Sbjct: 1640 NKIGEGQFGKVYTAVNMSTGELMALKEMKFQPND----LQQLREMCDEIKIFEGIQHENL 1473
Query: 482 VTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNW 541
V + V + D++ + M Y D ++ E K ++ +++ V HLH+N
Sbjct: 1472 VKYYGVEV--HKDEMLMFMEYC--DTGTIEEAAKMGLPEYLIRRYTREIVLAVNHLHENS 1305
Query: 542 ILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTP-------VVVTQWYRAPELLL 594
I+HRD+K +N+ L+ G +K+GDFG + + LK++T +V T Y APE+
Sbjct: 1304 IVHRDIKGANIFLTSNGHVKLGDFGCSVK----LKSHTTMPGEFHNLVGTTAYMAPEVFT 1137
Query: 595 GAKE--YSTAVDMWSVGCIFGELLTQK 619
+ Y A D+WS+GC+ E+ T K
Sbjct: 1136 QNDQGGYGRAADIWSLGCVVIEMATGK 1056
>03294
Length = 1684
Score = 87.0 bits (214), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 49/130 (37%), Positives = 73/130 (56%)
Frame = -1
Query: 603 VDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKMTFSE 662
VD+WS+G IF ++L + P+F G+SEIDQ+ K+F+ +GTP+E+ WP + +LP M F
Sbjct: 1672 VDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKLPAFNGM-FPL 1496
Query: 663 HPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSMFPTW 722
L + L S G DL+ + L P +RIS + L+H YF + P P+
Sbjct: 1495 WKEGKLSETLTDLDS-LGLDLIERTLKCDPAQRISCKKMLQHAYFLNVDTSVKPVDVPS- 1322
Query: 723 PAKSEQQRVK 732
P S R+K
Sbjct: 1321 PEHS*STRLK 1292
>18921
Length = 697
Score = 85.5 bits (210), Expect = 8e-17, Method: Compositional matrix adjust.
Identities = 57/205 (27%), Positives = 109/205 (53%), Gaps = 6/205 (2%)
Frame = +2
Query: 422 FQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNI 481
F L ++ EG+YG V+++ K+T +++A+K++ ++ + + ++EI+ + + I
Sbjct: 35 FDILGKLGEGSYGSVFKSLHKETGQVLAIKQVPVDTDLQEI----IKEISIMQQCDSKYI 202
Query: 482 VTVREIVVGS---NMDKIYIVMNYV-EHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHL 537
V GS N D ++IVM Y + +M + + E+ T++ L+G+ +L
Sbjct: 203 VKYY----GSYFKNTD-LWIVMEYCGAGSVSDIMRLRNKTLVEREIATILYYTLKGLXYL 367
Query: 538 HDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELL--LG 595
H +HRD+K N+LL++ G K+ DFG+A + + V+ T ++ APE++ +G
Sbjct: 368 HSRRKIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTPYWMAPEVIQEIG 547
Query: 596 AKEYSTAVDMWSVGCIFGELLTQKP 620
Y D+WS+G E+ KP
Sbjct: 548 ---YDCVADIWSLGITALEMAEGKP 613
>06405
Length = 1965
Score = 82.8 bits (203), Expect = 4e-16, Method: Compositional matrix adjust.
Identities = 63/205 (30%), Positives = 102/205 (49%), Gaps = 8/205 (3%)
Frame = +1
Query: 421 EFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILK-AQHP 479
E +R+ G YG VY A K+ ++IVA+K LK ++ + E I+K +HP
Sbjct: 262 EIAMKHRLGGGQYGDVYEAMWKRYNKIVAVKTLK----EDTMALNDFLEEAAIMKEMKHP 429
Query: 480 NIVTVREIVVGSNMDKIYIVMNYVEHD--LKSLMETMKQPFLPGEVKTLMIQLLRGVKHL 537
N+V + + V + YIV ++ H L L + ++ P + + Q+ G+ +L
Sbjct: 430 NLVQL--LGVCTREPPFYIVTEFMPHGNLLDYLRSSTREENGPTALMYMATQIASGMAYL 603
Query: 538 HDNWILHRDLKTSNLLLSHAGILKVGDFGLAR-----EYGSPLKAYTPVVVTQWYRAPEL 592
+HRDL N L++ + ++KV DFGLAR Y + + A P+ +W APE
Sbjct: 604 ETKNFIHRDLAARNCLVADSNMVKVADFGLARLMKDDTYTAHIGAKFPI---KW-TAPE- 768
Query: 593 LLGAKEYSTAVDMWSVGCIFGELLT 617
L +ST D+W+ G + EL T
Sbjct: 769 GLAFNRFSTRSDIWAFGVLLWELAT 843
>13592
Length = 980
Score = 82.4 bits (202), Expect = 6e-16, Method: Compositional matrix adjust.
Identities = 80/295 (27%), Positives = 138/295 (46%), Gaps = 13/295 (4%)
Frame = +2
Query: 427 RIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVRE 486
+I +G +G VY A + T E++A+K + ++ + E+ + +H N+V
Sbjct: 5 KIGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETRALKNVAEELKILEGIKHKNLVRYYG 184
Query: 487 IVVGSNMDKIYIVMNYV-EHDLKSLMETMKQPFLPGEV-KTLMIQLLRGVKHLHDNWILH 544
I V + +++ I M E L+SL+E LP + + QLL GV LH + I+H
Sbjct: 185 IEV--HREELLIFMELCSEGTLESLVELTGG--LPEALSRRFTAQLLSGVAELHKHGIVH 352
Query: 545 RDLKTSNL-LLSHAGILKVGDFGLAREYGSPLKAYTPV-------VVTQWYRAPELL--L 594
RD+KT+N+ L+ + LK+GDFG A + ++A+T V V TQ Y APE+
Sbjct: 353 RDIKTANIFLVDGSNSLKLGDFGSAVK----IQAHTTVPGELQGYVGTQAYMAPEVFTKT 520
Query: 595 GAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGY-SELP 653
+ + D+WSVGC+ E+ + K + W + S
Sbjct: 521 NSDGHGRLADIWSVGCVVVEMASGK------------------------RPWAQFDSNFQ 628
Query: 654 VVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFR 708
++ K+ E P + LS +G D ++ L + P +R+SA + L+ + +
Sbjct: 629 IMFKVGMGEKP------QAPESLSQEGHDFIDHCLQHDPKQRLSAIELLEQNFCK 775
>12721
Length = 821
Score = 81.6 bits (200), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 53/196 (27%), Positives = 106/196 (54%)
Frame = +1
Query: 427 RIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVRE 486
+I EG+ G+V A + ++ A+K++ + K++ + E+ + HPNIV +
Sbjct: 109 KIGEGSTGIVCIATSRDGRQM-AVKKMDLRKQQRRELL--FNEVVVMRDYHHPNIVEMYN 279
Query: 487 IVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRD 546
+ + D++++VM ++E + + T + ++ T+ L+ + LH N ++HRD
Sbjct: 280 SYLVN--DELWVVMEFMEGGALTDIVTNNR-MDEVQIATVCRACLKALAFLHANGVIHRD 450
Query: 547 LKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMW 606
+K+ ++LLSH G +K+ DFG + L+ +V T ++ APE ++ Y VD+W
Sbjct: 451 IKSDSILLSHDGKVKLXDFGFCAQVTQDLQKRKSLVGTPYWMAPE-VISRLPYGPEVDIW 627
Query: 607 SVGCIFGELLTQKPLF 622
S+G + E++ +P F
Sbjct: 628 SLGIMVMEMIDAEPPF 675
>01718
Length = 959
Score = 79.7 bits (195), Expect = 4e-15, Method: Compositional matrix adjust.
Identities = 60/218 (27%), Positives = 107/218 (49%), Gaps = 6/218 (2%)
Frame = +3
Query: 412 ALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREIN 471
A+ +++F C +I G + V++ + T +++ALK M + LRE+
Sbjct: 126 AVSALTRLDDFIC-EKIGAGFFSEVFKVTHRITGQVMALKMNTMTSNRHNM----LREVQ 290
Query: 472 TILKAQHPNIVTVREIVVGSNMDKIYIVMNYV-EHDLKSLMETMKQPFLPGEVKTLMIQL 530
+ + QH NI+ + V +++ + Y+ +L+ L+E + + L + L
Sbjct: 291 LLNRLQHANILRFMGVCVHEG--QLHALTEYIPSGNLEQLLEKKDEELPWTQRIQLTLGL 464
Query: 531 LRGVKHLHDNWILHRDLKTSNLLL----SHAGILKVGDFGLAREYGSPL-KAYTPVVVTQ 585
RG+ +LH +HRDL + N+L+ +H + DFGLA + PL K P V +
Sbjct: 465 ARGLDYLHSTRFIHRDLTSKNILIRREDNHGYHAVIADFGLATKIPDPLDKEKLPTVGSP 644
Query: 586 WYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFP 623
++ APE+L G Y+ D++SVG I E+ + P P
Sbjct: 645 YWMAPEVLNG-HFYNERADLFSVGIIMCEITARIPADP 755
>09606
Length = 1300
Score = 77.8 bits (190), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 82/314 (26%), Positives = 134/314 (42%), Gaps = 24/314 (7%)
Frame = -3
Query: 419 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 478
+E F + +G + ++Y+ + K T VA+ + EK K ++R + I H
Sbjct: 1118 MENFVLYEELGKGEHSIIYKGRRKGTINFVAIHCI--EKCKRPEVTNTVRMTHDI---SH 954
Query: 479 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPF-LP-GEVKTLMIQLLRGVKH 536
PN+V E SN +++V+ SL + + Q LP ++ I L+ G+ +
Sbjct: 953 PNVVQFHEWYETSN--HLWLVVELCTGG--SLADILAQDHHLPETSIRDFGIHLVTGLHY 786
Query: 537 LHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAY------------------ 578
+H IL DL+ S +LL +G+LK DFGL++ G L+
Sbjct: 785 IHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQWNIQSAEE 606
Query: 579 ----TPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKV 634
P + Y APE+ GA E S D+W++GC+F E+ + P F G + +KV
Sbjct: 605 MMKQVPTSGSPTYMAPEVFQGA-EPSIMSDLWALGCVFYEMFSGHPPFLGETYDITKDKV 429
Query: 635 FKELGTPSEKIWPGYSELPVVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGR 694
K +P LP VK S P S + +L+ L R
Sbjct: 428 LN-------KEFP----LPKVKGSRLSAKP------------SPEFLNLLESLLQKDSTR 318
Query: 695 RISAEDGLKHEYFR 708
R+S +KH +++
Sbjct: 317 RLSWASLVKHAFWQ 276
>03508
Length = 1463
Score = 76.6 bits (187), Expect = 4e-14, Method: Compositional matrix adjust.
Identities = 39/122 (31%), Positives = 72/122 (59%), Gaps = 2/122 (1%)
Frame = +1
Query: 504 EHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGI-LKV 562
EH + + + Q F +++ + +L++ + H I+HRD+K N+++ H L++
Sbjct: 820 EHVNNTDFKQLYQTFTDYDIRFYLYELMKALDFCHSMGIMHRDVKPHNVMIDHENKKLRL 999
Query: 563 GDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQK-PL 621
D+GLA E+ P Y V +++++ PELLL + Y ++DMWS+GC+F ++ +K PL
Sbjct: 1000IDWGLA-EFYHPGMEYNVRVASRYFKGPELLLDYQMYDYSLDMWSLGCMFASMIFRKEPL 1176
Query: 622 FP 623
P
Sbjct: 1177LP 1182
Score = 35.0 bits (79), Expect = 0.11, Method: Compositional matrix adjust.
Identities = 27/114 (23%), Positives = 51/114 (44%), Gaps = 12/114 (10%)
Frame = +2
Query: 606 WSVG----CIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKMTFS 661
W+ G C+ + P F G+ DQ+ ++ K LGT + ++ + + F+
Sbjct: 1118 WTCGVWAACLPA*SSGKSPFFHGHDNYDQLVRIAKVLGT--DDLYGYIEKYQIDLDPRFN 1291
Query: 662 EHPYNNLRKRF--------GALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYF 707
+ + RKR+ L+S + D ++K L Y R++A + + H YF
Sbjct: 1292 DILGRHSRKRWERFVHSENQHLISPEALDFLDKLLRYDHNERLTAREAMDHPYF 1453
>20559
Length = 430
Score = 66.2 bits (160), Expect(2) = 1e-13, Method: Compositional matrix adjust.
Identities = 31/82 (37%), Positives = 58/82 (70%)
Frame = -2
Query: 407 PKYLPALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITS 466
P +L + +++++ L +I EGTYG V++AK+++T EIVALKR++++ + EG P ++
Sbjct: 414 PTHLHSF*LKHKMQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSA 235
Query: 467 LREINTILKAQHPNIVTVREIV 488
LREI + + +H NIV + +++
Sbjct: 234 LREICLLKELKHRNIVRLHDVL 169
Score = 29.3 bits (64), Expect(2) = 1e-13, Method: Composition-based stats.
Identities = 14/36 (38%), Positives = 19/36 (52%)
Frame = -3
Query: 502 YVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHL 537
Y + DLK +T P VK+ + QLLRG+ L
Sbjct: 134 YCDQDLKKYFDTCNGEIDPDTVKSFLHQLLRGLGFL 27
>12453
Length = 680
Score = 74.3 bits (181), Expect = 2e-13, Method: Composition-based stats.
Identities = 41/100 (41%), Positives = 55/100 (55%)
Frame = +3
Query: 608 VGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKMTFSEHPYNN 667
VGCIF E+ +PLFPG++ D+++ +FK LGTP+E P S P + +
Sbjct: 6 VGCIFYEMACGRPLFPGSTVEDELHLIFKTLGTPTEDSLPSISRNPDFLALNLPHYQGEA 185
Query: 668 LRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYF 707
L L SD G DL+ KFL Y R+SA D LKH +F
Sbjct: 186 LITIAPRLDSD-GLDLLAKFLKYNAKIRVSAADSLKHSFF 302
>14420
Length = 528
Score = 73.2 bits (178), Expect = 4e-13, Method: Compositional matrix adjust.
Identities = 44/156 (28%), Positives = 90/156 (57%), Gaps = 2/156 (1%)
Frame = +2
Query: 467 LREINTILKAQHPNIVT-VREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFL-PGEVK 524
+ EI + + Q+PNIV + +VG +++++VM ++ SL + + + + G++
Sbjct: 44 INEILVMRENQNPNIVNYLDSYLVG---EELWVVMEFLAGG--SLTDVVTETCMDEGQIA 208
Query: 525 TLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVT 584
+ + L+ ++ LH+N ++HRD+K+ N+LL G +K+ DFG + + +V T
Sbjct: 209 AVCRECLQALEFLHENQVIHRDIKSDNILLGMDGSVKLTDFGFCAQLSPEQSKRSTMVGT 388
Query: 585 QWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKP 620
++ APE ++ K+Y VD+WS+G + E++ +P
Sbjct: 389 PYWMAPE-VVTRKQYGPTVDIWSLGVMCIEMIEGEP 493
>15910
Length = 1361
Score = 71.2 bits (173), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 49/125 (39%), Positives = 67/125 (53%), Gaps = 3/125 (2%)
Frame = +2
Query: 530 LLRGVKHLHDNWILHRDLKTSNLL---LSHAGILKVGDFGLAREYGSPLKAYTPVVVTQW 586
+L GV+++H N ++HRDLK NLL ++ LK+ DFGL+R P + V T
Sbjct: 491 ILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLADFGLSRII-EPEVQMSTVCGTPG 667
Query: 587 YRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIW 646
Y APE+L G K Y+ +VDMWSVG I LL F +E + K+ K E+ W
Sbjct: 668 YCAPEVLKGDK-YTPSVDMWSVGVIAYILLCGYEPFFAENEFEMYRKIIKGEYKFDEEYW 844
Query: 647 PGYSE 651
SE
Sbjct: 845 SEISE 859
>26560
Length = 398
Score = 68.2 bits (165), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 37/119 (31%), Positives = 66/119 (55%), Gaps = 4/119 (3%)
Frame = -1
Query: 518 FLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKA 577
F EV+ +++ G++H+H ++++RDLK +N+LL G +++ D GLA ++ K
Sbjct: 365 FTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGLACDFSK--KR 192
Query: 578 YTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLF----PGNSEIDQIN 632
V T Y APE+L+ + Y ++ D +S GC+ +LL F G + ID++
Sbjct: 191 PHASVGTHGYMAPEVLMKGQSYDSSADWFSFGCMLYKLLKGHSPFRQHNQGQARIDRMT 15
>19761
Length = 473
Score = 65.5 bits (158), Expect = 8e-11, Method: Compositional matrix adjust.
Identities = 36/104 (34%), Positives = 60/104 (57%)
Frame = -3
Query: 536 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLG 595
H H ILHRDLK N+ ++ G +++GD GLAR+ P T V T Y +PE +L
Sbjct: 372 HTHTPVILHRDLKPQNIYVTEKGDVRLGDLGLARKLTGPADFATSQVGTIMYLSPE-ILS 196
Query: 596 AKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELG 639
+ Y++ D+WS+GC+F ++ +K G+ E+ + + + +G
Sbjct: 195 QQPYNSKSDIWSLGCVFYDITGKK----GSDEMGVMFLLVQVMG 76
>18484
Length = 635
Score = 65.1 bits (157), Expect = 9e-11, Method: Compositional matrix adjust.
Identities = 35/106 (33%), Positives = 58/106 (54%)
Frame = +1
Query: 529 QLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYR 588
++ G+ LHD I++RDLK N++L G +K+ DFG+ +E + T Y
Sbjct: 67 EIAVGLFFLHDQGIIYRDLKLDNVMLDSEGHIKIADFGMCKEGMTGDATTRTFCGTPDYI 246
Query: 589 APELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKV 634
APE++L + YS +VD W+ G + E+L +P F G E + + +
Sbjct: 247 APEIVL-YQPYSKSVDWWAYGVLLFEMLAGQPPFDGEDEDELFSSI 381
>21578
Length = 524
Score = 64.3 bits (155), Expect = 2e-10, Method: Composition-based stats.
Identities = 26/33 (78%), Positives = 31/33 (93%)
Frame = +2
Query: 402 LKQELPKYLPALQGCRSVEEFQCLNRIEEGTYG 434
LK++LP YLPA+QGCR+VEEF C+NRIEEGTYG
Sbjct: 425 LKEDLPVYLPAIQGCRNVEEFHCMNRIEEGTYG 523
>27546
Length = 426
Score = 62.8 bits (151), Expect = 5e-10, Method: Composition-based stats.
Identities = 38/113 (33%), Positives = 60/113 (53%), Gaps = 2/113 (1%)
Frame = -1
Query: 459 KEGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQ-- 516
K+ FP RE+ + + HPNI+ + I+ KI+I M Y E ++ +K+
Sbjct: 348 KKFFP----RELEILTRLDHPNIIQIHSIL--QRGPKIFIFMRYAEKG--DMLSHIKKTG 193
Query: 517 PFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAR 569
P + K Q+ + +++LH + I HRDLK N+LLS +K+ DFG AR
Sbjct: 192 PIDEAQTKVWFFQMAKALQYLHSHDIAHRDLKCENILLSKRLNVKIADFGFAR 34
>03240
Length = 1683
Score = 61.6 bits (148), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 62/262 (23%), Positives = 105/262 (40%), Gaps = 48/262 (18%)
Frame = -3
Query: 422 FQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNI 481
F+ + + G +G V + T + A+K L+ + + ++ IL A+ N
Sbjct: 1285 FEKIKTLGVGAFGEVSLCRKNDTGMLYAMKTLRKSDVLKRNQVAHVKAERDIL-AEADNE 1109
Query: 482 VTVREIVVGSNMDKIYIVMNYVEH-DLKSL---METMKQPFLPGEVKTLMIQLLRGVKHL 537
V+ + + +Y VM+YV DL L ME + +P + + +L++ ++ +
Sbjct: 1108 WVVKLYYSFQDHNYLYFVMDYVPGGDLMGLLIRMEILDEPL----ARFYVAELVQAIESV 941
Query: 538 HDNWILHRDLKTSNLLLSHAGILKVGDFGL-------------------AREYGSPLKAY 578
H +HRD+K N+L+ G +K+ DFGL AR+ +K
Sbjct: 940 HRMGFIHRDIKPDNILIDRNGHIKLTDFGLCTGFRWTHNSKYYQRDGTHARQDSMEVKCQ 761
Query: 579 T-------------------------PVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFG 613
+V T Y APE+L Y++ D WSVG I
Sbjct: 760 LDEQCQCEILKPLERRRKREQRCLAHSLVGTPNYIAPEVLSRLGGYTSVCDWWSVGVILF 581
Query: 614 ELLTQKPLFPGNSEIDQINKVF 635
E+L P F N+ + KV
Sbjct: 580 EMLVGHPPFYANTPAETQYKVI 515
>14116
Length = 1017
Score = 61.6 bits (148), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 61/205 (29%), Positives = 99/205 (48%), Gaps = 14/205 (6%)
Frame = -1
Query: 428 IEEGTYGVVYRA----KDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVT 483
I +G +G V R ++K D +VA+K L +E + L+E + H N++T
Sbjct: 612 IGKGNFGCVKRGFLTLPEQKGDILVAVKTLHNNNPREIELQSFLQEALIMKDFHHSNVLT 433
Query: 484 VREIVVGSNMDKI-YIVMNYVEHD--LKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDN 540
+ I + N+D + +V+ +++H L + + QP + ++ + + RG+ +L
Sbjct: 432 LIGICL--NLDDMPLVVLPFMKHGDLLTYIRDDQHQPTIK-DLIMYGVDIARGMDYLAGL 262
Query: 541 WILHRDLKTSNLLLSHAGILKVGDFGLAR-----EYGSP--LKAYTPVVVTQWYRAPELL 593
+HRDL N +L +KV DFGLAR EY S KA PV +W L
Sbjct: 261 KFVHRDLAARNCMLDEDFHVKVADFGLARDIYEKEYYSSENKKAKLPV---KWMALESLE 91
Query: 594 LGAKEYSTAVDMWSVGCIFGELLTQ 618
G Y + D+WS G + ELLT+
Sbjct: 90 KG--NYDSKTDVWSYGVVLWELLTR 22
>30755
Length = 1137
Score = 61.2 bits (147), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 35/94 (37%), Positives = 51/94 (54%), Gaps = 3/94 (3%)
Frame = +2
Query: 529 QLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLARE---YGSPLKAYTPVVVTQ 585
+++ + +LH I++RDLK NLLL G +KV DFGL +E YG K + T
Sbjct: 56 EIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCKEDITYGRTTKTFCG---TP 226
Query: 586 WYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQK 619
Y APE +L +Y AVD W G + E++ +
Sbjct: 227 EYLAPE-VLDDNDYGRAVDWWGTGVVMYEMICGR 325
>13066
Length = 551
Score = 61.2 bits (147), Expect = 2e-09, Method: Composition-based stats.
Identities = 52/185 (28%), Positives = 87/185 (47%), Gaps = 6/185 (3%)
Frame = +3
Query: 431 GTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREIVVG 490
GT+ Y K +I+ ++ ++ ++ FP RE++ + K HP I+ + I+
Sbjct: 24 GTFNDGYGRNIKLACKIIDKEKAPVDFVEKFFP----RELDLLTKLDHPYIIQIHSIL-- 185
Query: 491 SNMDKIYIVMNYVEH-DLKSLMETMKQPFLP-GEVKTLMIQLLRGVKHLHDNWILHRDLK 548
K +I M + E DL + ++ + F+ + K Q+ + +LH + HRDLK
Sbjct: 186 QRXPKNFIFMRFAERGDLLTYIQEVG--FVKEKQAKIWFYQMTTALNYLHSYDVAHRDLK 359
Query: 549 TSNLLLSHAGILKVGDFGLA----REYGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVD 604
N+LLS +K+ DFG A E G + T + Y APE++ GA D
Sbjct: 360 CENILLSSHFNVKLADFGFACACITESGEKYMSRT-YCGSAAYAAPEIVYGAPYAPKVAD 536
Query: 605 MWSVG 609
WS+G
Sbjct: 537 AWSLG 551
>13212
Length = 1067
Score = 61.2 bits (147), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 46/206 (22%), Positives = 93/206 (45%), Gaps = 4/206 (1%)
Frame = -1
Query: 507 LKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFG 566
L S+M +++P ++ + ++ + LH + ++HRD+K N+LL+ G +K+ DFG
Sbjct: 1022 LDSIMVDLEKPMTEAQICYVCHEMCMALDFLHRHHVIHRDIKAGNVLLTIDGEVKLADFG 843
Query: 567 LAREYGSPLKAYTPVVVTQWYRAPELLLGA----KEYSTAVDMWSVGCIFGELLTQKPLF 622
++ + + + T ++ APE++L Y D+WS+G E
Sbjct: 842 VSAKNTQTQQKRDTFIGTPYWMAPEVVLCETLKDTPYDFKADIWSLGVTLIE-------- 687
Query: 623 PGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKMTFSEHPYNNLRKRFGALLSDQGFD 682
F ++ P++++ P + V+ K+ S+ P K++ L D
Sbjct: 686 ------------FAQIEPPNKEMHP----MRVLIKIHKSDPPTLEKPKKWTKLFK----D 567
Query: 683 LMNKFLTYFPGRRISAEDGLKHEYFR 708
+ K L P R +A + L+H + +
Sbjct: 566 FIAKCLVKDPNLRPTAAELLEHPFMK 489
>28638
Length = 1458
Score = 60.8 bits (146), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 33/81 (40%), Positives = 51/81 (62%), Gaps = 2/81 (2%)
Frame = -1
Query: 542 ILHRDLKTSNLLLSHA--GILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEY 599
I+H DLK N+LL + +K+ DFG + + G + Y + +++YR+PE+LLG Y
Sbjct: 768 IIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQY---IQSRFYRSPEVLLGVP-Y 601
Query: 600 STAVDMWSVGCIFGELLTQKP 620
A+DMWS+GCI E+ T +P
Sbjct: 600 DLAIDMWSLGCILVEMHTGEP 538
Score = 29.6 bits (65), Expect = 4.5, Method: Compositional matrix adjust.
Identities = 15/52 (28%), Positives = 22/52 (42%), Gaps = 5/52 (9%)
Frame = -2
Query: 599 YSTAVDMWSVGC-----IFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKI 645
Y W + C + PLF G++E DQ+ K+ + LG P I
Sbjct: 617 YXXCPMTWPLTCGXWAVYWWRCTXGNPLFAGSNEFDQMMKIVEVLGVPPRHI 462
>26909
Length = 394
Score = 60.1 bits (144), Expect = 4e-09, Method: Compositional matrix adjust.
Identities = 38/119 (31%), Positives = 57/119 (47%), Gaps = 16/119 (13%)
Frame = +2
Query: 611 IFGELLTQKPLFPGNSE---------IDQINKVFKELGTPSEKIWPGYSELPVVKKMT-- 659
IF ELLT +P+F E DQ++++F +G P EK W +P +++T
Sbjct: 2 IFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFPQEKDWEDIRRMPEHQQLTKD 181
Query: 660 FSEHPYNNLR-----KRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLP 713
F Y N ++ + F L+ K LT P +RI++E +K YF E PLP
Sbjct: 182 FKRSSYVNCNLMKYMEKHKVKADSKAFHLLQKLLTMDPVKRITSEQAMKDPYFLEEPLP 358
>19094
Length = 898
Score = 58.9 bits (141), Expect = 8e-09, Method: Compositional matrix adjust.
Identities = 31/105 (29%), Positives = 58/105 (55%), Gaps = 2/105 (1%)
Frame = +1
Query: 507 LKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFG 566
+ +M + + E+ T++ L+G+ +LH +HRD+K N+LL++ G K+ DFG
Sbjct: 16 VSDIMRLRNKTLVEREIATILYYTLKGL*YLHSRRKIHRDIKAGNILLNNEGHAKLADFG 195
Query: 567 LAREYGSPLKAYTPVVVTQWYRAPELL--LGAKEYSTAVDMWSVG 609
+A + + V+ T ++ APE++ +G Y D+WS+G
Sbjct: 196 VAGQLTDTMAKRNTVIGTPYWMAPEVIQEIG---YDCVADIWSLG 321
>21808
Length = 1011
Score = 58.2 bits (139), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 56/201 (27%), Positives = 96/201 (47%), Gaps = 14/201 (6%)
Frame = +1
Query: 448 VALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDL 507
VA+K LK P L E + K +HP ++ + V + D I+I+ +++
Sbjct: 28 VAIKTLKSGTMD---PKDFLAEAQIMKKLRHPKLIQL--YAVCTQDDPIFIITELMKNG- 189
Query: 508 KSLMETMKQPFLPGEVKTLMI--------QLLRGVKHLHDNWILHRDLKTSNLLLSHAGI 559
SL+E FL G+ + L + Q+ G+ +L +HRDL N+L+S
Sbjct: 190 -SLLE-----FLQGKGRVLKLPALIDIGAQIACGMAYLESQNYIHRDLAARNILVSDNNT 351
Query: 560 LKVGDFGLAR-----EYGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGE 614
+K+ DFGLAR EY + + A P+ +W APE ++ D+WS G + E
Sbjct: 352 VKIADFGLARVIKEDEYEARVGARFPI---KW-TAPE-AANYNRFTIKSDVWSFGILLTE 516
Query: 615 LLTQKPL-FPGNSEIDQINKV 634
+T + +PG + + +++V
Sbjct: 517 TVTYGRVPYPGMTNAEVLHQV 579
>11185
Length = 473
Score = 57.0 bits (136), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 35/117 (29%), Positives = 56/117 (47%), Gaps = 22/117 (18%)
Frame = +1
Query: 523 VKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAY---- 578
++ I L+ G+ ++H IL DL+ S +LL +G+LK DFGL++ G L+
Sbjct: 7 IRDFGIHLVTGLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKF 186
Query: 579 ------------------TPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLT 617
P + Y APE+ GA E S D+W++GC+F E+ +
Sbjct: 187 AEAGDQWNIQSAEEMMKQVPTSGSPTYMAPEVFQGA-EPSIMSDLWALGCVFYEMFS 354
>28157
Length = 400
Score = 55.8 bits (133), Expect = 6e-08, Method: Composition-based stats.
Identities = 44/129 (34%), Positives = 67/129 (51%), Gaps = 8/129 (6%)
Frame = +3
Query: 448 VALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSNMDK-IYIVMNYVEHD 506
VA+KR++ E+EK+ F ++E+ + + HPNIV + G+ D + +VM Y E
Sbjct: 9 VAVKRIESEQEKKSF----MQELKQLSRVSHPNIVCL----YGACRDHPVCLVMEYAEGG 164
Query: 507 --LKSLMETMKQP-FLPGEVKTLMIQLLRGVKHLHD---NWILHRDLKTSNLLLSHAGI- 559
L + QP + ++Q GV++LH ++HRDLK NLLL G
Sbjct: 165 SLYNVLHGSGPQPQYTAAHAMNWLLQCALGVEYLHGMKPKALIHRDLKPPNLLLIQCGTK 344
Query: 560 LKVGDFGLA 568
LK+ DFG A
Sbjct: 345 LKICDFGTA 371
>27405
Length = 532
Score = 55.8 bits (133), Expect = 6e-08, Method: Compositional matrix adjust.
Identities = 28/87 (32%), Positives = 51/87 (58%)
Frame = -3
Query: 518 FLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKA 577
F EV+ +++ G++H+H ++++RDLK +N+LL G +++ D GLA ++ K
Sbjct: 263 FTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGLACDFSK--KK 90
Query: 578 YTPVVVTQWYRAPELLLGAKEYSTAVD 604
V T Y APE+L+ + Y ++ D
Sbjct: 89 PHASVGTHGYMAPEVLMKGQAYDSSAD 9
>19301
Length = 712
Score = 55.8 bits (133), Expect = 6e-08, Method: Compositional matrix adjust.
Identities = 43/149 (28%), Positives = 75/149 (50%), Gaps = 2/149 (1%)
Frame = +2
Query: 420 EEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHP 479
E L + G G V+ K E VA+K+++ KE + I +LR++N HP
Sbjct: 305 ESITDLEWLGSGAQGAVFLGK--LCAEEVAVKKVRDIKETD---IRNLRKLN------HP 451
Query: 480 NIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMK--QPFLPGEVKTLMIQLLRGVKHL 537
NI++ + + + I+M Y + L E ++ + P V Q+ G+ +L
Sbjct: 452 NIISFKGVC--TQAPCYCIIMEYCPYG--QLYEVLRDGKEIPPALVLDWSKQIASGMNYL 619
Query: 538 HDNWILHRDLKTSNLLLSHAGILKVGDFG 566
H + I+HRDLK+ N+L++ ++K+ DFG
Sbjct: 620 HSHKIIHRDLKSPNVLVAKNDVVKISDFG 706
>18287
Length = 678
Score = 55.8 bits (133), Expect = 7e-08, Method: Composition-based stats.
Identities = 35/119 (29%), Positives = 53/119 (44%), Gaps = 8/119 (6%)
Frame = -3
Query: 599 YSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKM 658
Y ++D+WSVGCIF ELL+++ LF + Q++ + +GTP + E
Sbjct: 673 YDYSIDIWSVGCIFAELLSRRILFQAQGPVQQLDMIINLVGTPRPEDMERACE------- 515
Query: 659 TFSEHPYNNLRKRFGALL--------SDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 709
H N +R L + + L+ + L P RISAE+ L H Y E
Sbjct: 514 GARNHILNQPFRRQNLLTLYNLSPHATHEAVRLLTRMLILNPKNRISAEEALSHPYLDE 338
>24241
Length = 413
Score = 55.5 bits (132), Expect = 9e-08, Method: Compositional matrix adjust.
Identities = 25/84 (29%), Positives = 54/84 (64%)
Frame = -2
Query: 425 LNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTV 484
L++I EGTYGVVY+ + + T +A+K++++ ++G P +++REI + + +H +
Sbjct: 328 LSKIGEGTYGVVYKCRHRATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTQXLVC 149
Query: 485 REIVVGSNMDKIYIVMNYVEHDLK 508
E V+ + +++++V ++ DLK
Sbjct: 148 LEDVIMED-ERLFLVFEFLSMDLK 80
>26711
Length = 405
Score = 55.5 bits (132), Expect = 9e-08, Method: Composition-based stats.
Identities = 39/111 (35%), Positives = 61/111 (54%), Gaps = 6/111 (5%)
Frame = -2
Query: 529 QLLRGVKHLHDNWILHRDLKTSNLLLSHAGI--LKVGDFGLAREYGSPLKAY----TPVV 582
Q+L ++H+H ++H DLK SNLLLS + +++ DFGLAR+ P + + TP
Sbjct: 392 QVLDILQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARKLYPPQETFLNHGTP-- 219
Query: 583 VTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINK 633
+ +PE L K STA D+W VG + LL+ + F +S + + K
Sbjct: 218 ---GFTSPE-ALDVKPISTASDVWGVGVLAYILLSGQSPFQADSATESLKK 78
>07940
Length = 1336
Score = 55.1 bits (131), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 35/112 (31%), Positives = 56/112 (50%), Gaps = 6/112 (5%)
Frame = -3
Query: 512 ETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLARE- 570
+ M + P ++ + Q+ RG+++L +HRDL N+L++ +LK+ DFGL R
Sbjct: 374 QDMLKMLTPKDLISYAYQVARGMEYLASKQCIHRDLAARNVLVAEEYVLKIADFGLTRNL 195
Query: 571 -----YGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLT 617
Y PV +W APE L K Y++ D+WS G + E+ T
Sbjct: 194 QQFDYYRKTTDGRLPV---KW-MAPEALFDRK-YTSKSDVWSYGVLLWEIFT 54
>31489
Length = 329
Score = 55.1 bits (131), Expect = 1e-07, Method: Composition-based stats.
Identities = 28/81 (34%), Positives = 50/81 (61%), Gaps = 4/81 (4%)
Frame = +3
Query: 477 QHPNIVTVREIVVGSN----MDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLR 532
+H NI+++REI+ + I++V + +E DL ++ + QP ++ + Q+LR
Sbjct: 24 KHDNIISIREILKPKDSYHDFKDIHVVFDLMESDLHRIIYS-DQPLTEEHIRYFLYQILR 200
Query: 533 GVKHLHDNWILHRDLKTSNLL 553
G+K++H ++HRDLK SNLL
Sbjct: 201 GLKYIHSANVVHRDLKPSNLL 263
>17253
Length = 483
Score = 53.1 bits (126), Expect = 4e-07, Method: Composition-based stats.
Identities = 44/140 (31%), Positives = 67/140 (47%), Gaps = 14/140 (10%)
Frame = -1
Query: 456 EKEKEGFPITSLREINTILK-AQHPNIVTVREIVVGSNMDKIYIVMNYVEH-DLKSLMET 513
+ EK F LRE++ + K +HPN+V+ S D I+M + H DL S +
Sbjct: 426 DAEKSEF----LRELSIMRKLPRHPNVVSFMGCCTMS--DPALILMEFCCHGDLLSFLRK 265
Query: 514 MKQP----FLPGEVKTLM--------IQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILK 561
++P FL L + + RG+ H+ +N I+HRD+ N+L+S + K
Sbjct: 264 -RRPDRTVFLTSTANDLTARDFFSFALHVARGMAHVANNKIVHRDVAARNVLISERNVCK 88
Query: 562 VGDFGLAREYGSPLKAYTPV 581
V DFGL+R G Y V
Sbjct: 87 VSDFGLSRRVGDQNDVYEIV 28
>04852
Length = 1462
Score = 52.4 bits (124), Expect = 7e-07, Method: Compositional matrix adjust.
Identities = 30/90 (33%), Positives = 48/90 (53%)
Frame = +1
Query: 528 IQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWY 587
Q+ RG++ L +HRDL N+L++ +LK+ DFGL+R K + +W
Sbjct: 346 FQIARGMEFLASRKCIHRDLAARNVLVTEEHVLKIADFGLSRTGDYYKKRSGGRLPVKWM 525
Query: 588 RAPELLLGAKEYSTAVDMWSVGCIFGELLT 617
APE L + Y+T D+WS G + E+ +
Sbjct: 526 -APEALFDMR-YTTKSDVWSFGVVLWEIFS 609
>18401
Length = 463
Score = 52.0 bits (123), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 39/144 (27%), Positives = 66/144 (45%), Gaps = 14/144 (9%)
Frame = -3
Query: 578 YTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKE 637
++ +V T+ YRAPE++L +S D+WSVGCI EL T LF + + + + +
Sbjct: 461 HSTIVSTRHYRAPEVILELG-WSHPCDVWSVGCIMFELYTGYTLFQTHDNKEHLAMMERI 285
Query: 638 LGTPSEKI--------WPGYSELPVVKKMTFSEHPYNNLRKRFGALL------SDQGFDL 683
LG+ ++ + + L V ++ + + + N + + Q FDL
Sbjct: 284 LGSLPYRMAKKTKKQKYFHHGRLDVPERSSMARYVRENTKPLLRYVKDRENKDHQQLFDL 105
Query: 684 MNKFLTYFPGRRISAEDGLKHEYF 707
M K L Y R S L+H +F
Sbjct: 104 MKKLLAYEASSRYSLLQALQHPFF 33
>00715
Length = 1788
Score = 52.0 bits (123), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 47/173 (27%), Positives = 81/173 (46%), Gaps = 25/173 (14%)
Frame = +1
Query: 477 QHPNIVTVREIVVGSNM-DKIYIVMNYV-EHDLKSLMETMKQPFLPGEVKTLMIQLLRGV 534
+H N+V++ D ++ M YV +L++++ +Q +L +Q+ RG+
Sbjct: 100 RHVNVVSILGATSLHRFEDGAWLAMEYVGPLNLQTILNDHQQDIDSSMRLSLALQMARGL 279
Query: 535 KHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREY---------------GSPLKAYT 579
+LH I+H DLK +N LL+ L++ DFG + G+ L+ T
Sbjct: 280 HYLHSINIVHLDLKPANCLLTRDLKLRIADFGCCHQLTPTGLDMGEREGGMAGNELE-LT 456
Query: 580 PV--------VVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPG 624
PV T YRAPELL G + S D++S+G ++ T++ + G
Sbjct: 457 PVQGAWKNELAGTLAYRAPELLKGLQP-SVRSDVYSLGITLWQMCTRQGPYEG 612
>12672
Length = 773
Score = 51.2 bits (121), Expect = 2e-06, Method: Composition-based stats.
Identities = 31/89 (34%), Positives = 50/89 (56%), Gaps = 4/89 (4%)
Frame = +3
Query: 533 GVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREY----GSPLKAYTPVVVTQWYR 588
G+++L+DN +HRD+KT+N+LL KVGDF G ++ + V+ T Y
Sbjct: 27 GIQYLNDNGHVHRDIKTANILLDSEYTAKVGDFATVVSAPSGEGKTVQNASVVIGTAAYL 206
Query: 589 APELLLGAKEYSTAVDMWSVGCIFGELLT 617
APE + + ST +D +S G + E++T
Sbjct: 207 APEAI--HFDVSTKLDSYSFGVVLLEVIT 287
>21079
Length = 878
Score = 51.2 bits (121), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 34/91 (37%), Positives = 50/91 (54%), Gaps = 2/91 (2%)
Frame = +1
Query: 529 QLLRGVKHLHDNWILHRDLKTSNLLL--SHAGILKVGDFGLAREYGSPLKAYTPVVVTQW 586
Q+ GV ++H ILH DLK N+L ++ +K+ DFGLAR Y P + + T
Sbjct: 151 QICSGVGYMHTQSILHLDLKPENVLCVSDNSNQIKIIDFGLARFY-KPGDSLQVLFGTPE 327
Query: 587 YRAPELLLGAKEYSTAVDMWSVGCIFGELLT 617
+ APE ++ E + DMWS+G I LL+
Sbjct: 328 FIAPE-VVNYDEINFTTDMWSIGVICYILLS 417
>16003
Length = 926
Score = 50.4 bits (119), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 35/99 (35%), Positives = 51/99 (51%)
Frame = -1
Query: 615 LLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKMTFSEHPYNNLRKRFGA 674
LL + P PG++++DQ+ K+F LGTP+E WP + LP + F L++ F A
Sbjct: 926 LLIRLPFLPGDTDLDQLGKIFNMLGTPTETEWPAVTSLP--DYIQFKHCQKQPLKEIFTA 753
Query: 675 LLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLP 713
D +L++K L P R +A LK YF P P
Sbjct: 752 -AGDDLLELLDKLLAMNPLHRCTATQALKMPYFSNKPYP 639
>00392
Length = 668
Score = 50.4 bits (119), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 46/163 (28%), Positives = 74/163 (45%), Gaps = 6/163 (3%)
Frame = +3
Query: 477 QHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTL---MIQLLRG 533
QHPNIV + N +++ E ++T + F VK L Q+L+G
Sbjct: 105 QHPNIVRFFDYWEEHNHRNRKVIILVTELMTSGTLKTYLKRFKKPNVKILKNWCRQVLKG 284
Query: 534 VKHLHDNW--ILHRDLKTSNLLLSH-AGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAP 590
+ LH ++HRDLK N+ ++ G +K+GD GLA V+ T + AP
Sbjct: 285 LYFLHTRTPPVIHRDLKCDNIFITGPTGSVKIGDLGLATLKNQSFAK--SVIGTPEFMAP 458
Query: 591 ELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINK 633
E+ + Y AVD+++ G E+ + + + S QI K
Sbjct: 459 EMY--EEHYDEAVDVYAFGMCMLEMASSEYPYSECSNAAQIYK 581
>12786
Length = 460
Score = 50.1 bits (118), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 38/117 (32%), Positives = 58/117 (49%), Gaps = 23/117 (19%)
Frame = -3
Query: 529 QLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLA----REYGSPLKAYTPVVVT 584
++LR VK LH+ ++H DLK +N +L AG LK+ DFG+A ++ S LK V T
Sbjct: 386 EMLRAVKALHNEGVIHSDLKPANFMLV-AGNLKLIDFGIANTLQQDKTSVLK--DSRVGT 216
Query: 585 QWYRAPELLLGAKE-----------------YSTAV--DMWSVGCIFGELLTQKPLF 622
Y +PE ++ A + Y V D+WS+GCI ++ + F
Sbjct: 215 PSYMSPEAIMAACDDSADDSMEEDGHRTKPKYKVGVRSDVWSLGCILYNMVYGRTPF 45
>17300
Length = 480
Score = 49.3 bits (116), Expect = 6e-06, Method: Composition-based stats.
Identities = 31/90 (34%), Positives = 51/90 (56%), Gaps = 5/90 (5%)
Frame = +1
Query: 533 GVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLK--AYTP---VVVTQWY 587
G+ L D +HRDL N+L++ + KV DFGL+RE S AYT + +W
Sbjct: 10 GMGXLADMGYVHRDLAARNILVNEILVCKVADFGLSREIESDTTEGAYTTKGGKIPVRW- 186
Query: 588 RAPELLLGAKEYSTAVDMWSVGCIFGELLT 617
APE + +++++A D+WS G + E+++
Sbjct: 187 TAPE-AIAYRKFTSASDVWSFGVVMWEVMS 273
>31885
Length = 529
Score = 47.4 bits (111), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 46/161 (28%), Positives = 73/161 (45%), Gaps = 4/161 (2%)
Frame = -2
Query: 470 INTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQ 529
++ + + HP +V + D +V ++ DL+ M+ + F VK + Q
Sbjct: 519 VDMLTRLDHPFLVNLW-YAFQDEEDLFMVVDLFLGGDLRYHMQQ-EVSFREDCVKFYLCQ 346
Query: 530 LLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRA 589
L + +L I+HRD+K N+LL G V DF +A + A T T+ Y A
Sbjct: 345 LALVLDYLRSQKIVHRDIKPDNILLDEQGHCHVTDFNIATQLEDDELA-TSTSGTRPYMA 169
Query: 590 PELLLGA----KEYSTAVDMWSVGCIFGELLTQKPLFPGNS 626
PE+ A + Y VD WS+G ELL ++ F +S
Sbjct: 168 PEVYGVAINERRGYGFPVDWWSLGVSLFELLKKRRPFSVHS 46
>11780
Length = 1713
Score = 45.8 bits (107), Expect = 7e-05, Method: Compositional matrix adjust.
Identities = 51/202 (25%), Positives = 98/202 (48%), Gaps = 4/202 (1%)
Frame = +3
Query: 428 IEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREI 487
I +G +G VY+ + + VA+K+LK +K+ + L+E + + +H N+V + +
Sbjct: 621 IGKGDFGDVYKGMYR--GQPVAIKQLK---DKDRGEQSFLQEASVMTSLRHDNLVRLIGV 785
Query: 488 VVGSNMDKIYIVMNYV-EHDLKSLMETMKQPFLPGEVK-TLMIQLLRGVKHLHDNWILHR 545
V+G + I++V ++ + +L + + + + + + +++L ++HR
Sbjct: 786 VLG---ETIFLVTEFMGKGNLVEYLRSRGRSVITKKDQINFATDTCAAMEYLESKRLVHR 956
Query: 546 DLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEY--STAV 603
DL N+L+ G KV DFGLA+ +G + T V + APE L K + V
Sbjct: 957 DLAARNVLVHDDGKAKVSDFGLAK-FGDF--SQTSVKFPIKWTAPEALRENKIH*QVRHV 1127
Query: 604 DMWSVGCIFGELLTQKPLFPGN 625
++W + + G LL P N
Sbjct: 1128ELWHI--VMGNLLLWSSALP*N 1187
>05084
Length = 1324
Score = 44.7 bits (104), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 28/92 (30%), Positives = 43/92 (46%), Gaps = 4/92 (4%)
Frame = +2
Query: 622 FPGNSEIDQINKVFKELGTPS----EKIWPGYSELPVVKKMTFSEHPYNNLRKRFGALLS 677
PG+S +DQ+ ++ K LGTP+ ++ P YSE K HP+ K F
Sbjct: 2 LPGDSGVDQLVEIIKVLGTPTREQIREMNPNYSEF---KFPQIKAHPWT---KVFRPRTP 163
Query: 678 DQGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 709
+ L+++ L Y P RI + H +F E
Sbjct: 164 PEAIQLVSRLLEYTPSARIQPMEACAHAFFDE 259
>20640
Length = 1492
Score = 43.9 bits (102), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 26/79 (32%), Positives = 40/79 (50%), Gaps = 4/79 (5%)
Frame = +1
Query: 543 LHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAY----TPVVVTQWYRAPELLLGAKE 598
+HRDL T N L+ H ++K+ DFGLAR S + Y + +W +L +
Sbjct: 10 VHRDLATRNCLVGHDLVVKISDFGLARSVHS-VDYYRGSEHDAIPIRWMPLEAILYN--K 180
Query: 599 YSTAVDMWSVGCIFGELLT 617
+ST D+WS G + E+
Sbjct: 181 FSTQSDVWSFGVVLWEIFA 237
>07836
Length = 1478
Score = 43.9 bits (102), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 53/190 (27%), Positives = 85/190 (44%), Gaps = 20/190 (10%)
Frame = -1
Query: 446 EIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIV--TVREIVVGSNMDKIYIVMNYV 503
E VA+K +E F T L + T+L +H NI+ +I + +++++ +Y
Sbjct: 1475 ENVAVKIFFTTEEASWFRETELYQ--TVL-LRHENILGFIAADIKGTGSWTQLFLITDY- 1308
Query: 504 EHDLKSLMETMKQPFL-PGEVKTLMIQLLRGVKHLHDNW--------ILHRDLKTSNLLL 554
H+ SL + + L E+ L + G+ HLH I HRD+K+ N+L+
Sbjct: 1307 -HENGSLHDYLLSRVLDSSEMLALAHSAICGLAHLHIEIFGTRGKPAIAHRDIKSKNILV 1131
Query: 555 SHAGILKVGDFGLAREYGSPLK----AYTPVVVTQWYRAP---ELLLGAKEYST--AVDM 605
G + D GLA Y S A P T+ Y AP E+LL K + DM
Sbjct: 1130 KKNGTCCIADLGLAVRYISESNEVDVAPNPRQGTKRYMAPEVLEMLLNVKNFDAFKQADM 951
Query: 606 WSVGCIFGEL 615
++ G + E+
Sbjct: 950 YAFGLVMWEI 921
>17975
Length = 449
Score = 43.5 bits (101), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 35/146 (23%), Positives = 67/146 (45%), Gaps = 10/146 (6%)
Frame = +3
Query: 433 YGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSN 492
+ VV A+ T E VA+K + K E +E+ + QHPN+V + E++
Sbjct: 6 FAVVKLARHVFTGEKVAVKVIDKTKLDEVSRSHLFQEVRCMKLVQHPNVVRLYEVI--DT 179
Query: 493 MDKIYIVM---------NYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWIL 543
K+Y+++ +Y+ L E + + + Q++ + + H ++
Sbjct: 180 QTKLYLILELGDGGDMYDYIMRHSGGLEEKLAKRYFR--------QIVEAISYCHKLHVV 335
Query: 544 HRDLKTSNLLLSHA-GILKVGDFGLA 568
HRDLK N++ G++K+ DFG +
Sbjct: 336 HRDLKPENVVFFEKPGLVKLTDFGFS 413
>21433
Length = 590
Score = 42.0 bits (97), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 33/94 (35%), Positives = 50/94 (53%)
Frame = +2
Query: 527 MIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQW 586
+ QL +++ H ++HRD+K NLLL G LK+ DFG + +P T + T
Sbjct: 185 IYQLSSALEYCHYRKVIHRDIKPENLLLGLKGDLKIADFGWSVH--APSSRRTTMCGTLD 358
Query: 587 YRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKP 620
Y PE++ G K + VD+WS+G + E L P
Sbjct: 359 YLPPEMVEG-KTHDENVDLWSLGVLCYEFLVGTP 457
>07291
Length = 833
Score = 41.6 bits (96), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 28/96 (29%), Positives = 50/96 (52%), Gaps = 6/96 (6%)
Frame = +1
Query: 529 QLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGS--PLKAYT----PVV 582
Q+ G+ +L + ++HR+L N +++ G L++ D+G+ GS P YT P
Sbjct: 73 QIADGMAYLQEVKVVHRNLAARNCIVTEDGRLQLSDYGVT---GSLFPQSYYTADDSPAR 243
Query: 583 VTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQ 618
+ APE + +S+ D+W+ G + ELLT+
Sbjct: 244 DLVKWMAPE-TIDNFHFSSKSDVWAFGVVLWELLTR 348
>15549
Length = 470
Score = 39.7 bits (91), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 15/39 (38%), Positives = 29/39 (74%)
Frame = -1
Query: 417 RSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKM 455
R +EF+C+ ++ +G YG+V+RAK+K ++ A+KR+ +
Sbjct: 227 RFADEFECIEQMGKGGYGIVFRAKNKVDEQEYAVKRIAL 111
>02638
Length = 1490
Score = 39.3 bits (90), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 18/50 (36%), Positives = 30/50 (60%)
Frame = +1
Query: 587 YRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFK 636
+ APE+L G + Y A D+WSVGC+ E+ T +P + + + + +FK
Sbjct: 34 FMAPEVLRG-ESYGRACDVWSVGCVMIEMCTCRPPWNSHDISNHLALIFK 180
>18481
Length = 437
Score = 39.3 bits (90), Expect = 0.006, Method: Composition-based stats.
Identities = 28/99 (28%), Positives = 46/99 (46%), Gaps = 3/99 (3%)
Frame = -1
Query: 476 AQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVK 535
+HP + T+ G+ +VM + L+ L K+ F + + QLL ++
Sbjct: 326 GRHPGLPTMYH--YGTEKHFNALVMELLGPSLEELFVICKRRFTLKTILMVSDQLLSRLE 153
Query: 536 HLHDNWILHRDLKTSNLLLS---HAGILKVGDFGLAREY 571
+H +HRDLK N L+ H L + DFGL++ Y
Sbjct: 152 FIHQKCFIHRDLKPDNFLMGLGRHCHRLYIIDFGLSKRY 36
>26009
Length = 886
Score = 32.3 bits (72), Expect(2) = 0.006, Method: Compositional matrix adjust.
Identities = 12/33 (36%), Positives = 22/33 (66%)
Frame = +3
Query: 522 EVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLL 554
E K++M QL+ + +H ++HRD+K N+L+
Sbjct: 714 EAKSVMKQLVSALDFMHSKQLVHRDIKPENVLI 812
Score = 25.8 bits (55), Expect(2) = 0.006, Method: Compositional matrix adjust.
Identities = 23/93 (24%), Positives = 35/93 (37%), Gaps = 5/93 (5%)
Frame = +2
Query: 420 EEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREIN-----TIL 474
E + + GTYG V A+ + T VALK L T LRE +
Sbjct: 416 EHYDVCKELGRGTYGKVVLARCRHTGTQVALKLLPKS-------CTKLREFQREFQLSYF 574
Query: 475 KAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDL 507
+ H NI+ + + ++ + V DL
Sbjct: 575 LSPHANIIDTYNVAFQTRSSYVFAQEHAVLGDL 673
>14477
Length = 493
Score = 39.3 bits (90), Expect = 0.007, Method: Compositional matrix adjust.
Identities = 41/147 (27%), Positives = 70/147 (47%), Gaps = 4/147 (2%)
Frame = -1
Query: 427 RIEEGTYGVVYRAKDKKTD-EI-VALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTV 484
++ G +G V + + D EI VA+K LK ++E + K H +IV +
Sbjct: 469 KLGAGNFGSVMKGVCRLDDREIPVAIKVLKNADLDPSVQSELIKEAEVMKKMDHMHIVRL 290
Query: 485 REIVVGSNMDKIYIVMNYVEHDLKSLMETM-KQPFLP-GEVKTLMIQLLRGVKHLHDNWI 542
+ G M +V+ + L L + + K LP + LM Q+ +G+++L N
Sbjct: 289 IGLCEGETM---MLVLELAK--LGPLNKFLPKNKHLPLWNILELMWQVSQGMEYLEANKF 125
Query: 543 LHRDLKTSNLLLSHAGILKVGDFGLAR 569
+HRDL N+LL K+ DFG+++
Sbjct: 124 VHRDLAARNILLCDEHFAKISDFGMSK 44
>16708
Length = 1397
Score = 38.9 bits (89), Expect = 0.008, Method: Compositional matrix adjust.
Identities = 16/52 (30%), Positives = 31/52 (59%)
Frame = -1
Query: 520 PGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREY 571
P V + Q + ++H+H+ ++H D+K N+L+ G K+ D+G+A+ Y
Sbjct: 1097 PAMVCCIAGQXVCALEHIHELGVVHMDVKADNVLVDAHGNCKLTDYGIAQLY 942
>37602
Length = 804
Score = 38.9 bits (89), Expect = 0.008, Method: Compositional matrix adjust.
Identities = 20/72 (27%), Positives = 39/72 (54%)
Frame = -1
Query: 494 DKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLL 553
+K++I M Y + + P ++ + + L+G+ +LH +HRD+K +N+L
Sbjct: 300 EKLWIAMEYCGGGSMQDIYHVTGPLTEPQIAFVCRETLKGLHYLHRRGKMHRDIKGANIL 121
Query: 554 LSHAGILKVGDF 565
L+ G +K+ DF
Sbjct: 120 LTEEGDVKLADF 85
Score = 28.5 bits (62), Expect = 9.8, Method: Compositional matrix adjust.
Identities = 13/36 (36%), Positives = 21/36 (58%)
Frame = -2
Query: 405 ELPKYLPALQGCRSVEEFQCLNRIEEGTYGVVYRAK 440
E K +Q +++F+ + R+ GTYG VY+AK
Sbjct: 554 EYKKMQADIQRRNPLDDFELIQRVGSGTYGDVYKAK 447
>13078
Length = 773
Score = 37.7 bits (86), Expect = 0.019, Method: Compositional matrix adjust.
Identities = 31/125 (24%), Positives = 59/125 (47%), Gaps = 14/125 (11%)
Frame = -1
Query: 599 YSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKI--------WPGYS 650
+S D+WS+GCI EL T LF + + + + + LG+ ++ + +
Sbjct: 746 WSQPCDVWSIGCIMFELYTGYTLFQTHDNKEHLAMMERILGSLPYRMAKKTKKQKYFYHG 567
Query: 651 ELPVVKKMTFSEHPYNNLR--KRFGALLSD----QGFDLMNKFLTYFPGRRISAEDGLKH 704
L +K + + +N++ +R+ + Q FDLM+K L+Y R S ++H
Sbjct: 566 RLDWDEKSSAGRYVRDNVKPLRRYVKDPDNEDHQQLFDLMDKMLSYEVSTRYSLRQAMRH 387
Query: 705 EYFRE 709
+FR+
Sbjct: 386 PFFRK 372
>00486
Length = 797
Score = 35.4 bits (80), Expect = 0.090, Method: Compositional matrix adjust.
Identities = 18/50 (36%), Positives = 27/50 (54%)
Frame = -2
Query: 587 YRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFK 636
Y APE+L + AVD WS+G + ++LT P F + I+K+ K
Sbjct: 760 YMAPEILTRTG-HGKAVDWWSLGALMYDMLTGSPPFTAENRKKTIDKILK 614
>36481
Length = 806
Score = 33.5 bits (75), Expect = 0.31, Method: Compositional matrix adjust.
Identities = 37/149 (24%), Positives = 66/149 (44%), Gaps = 6/149 (4%)
Frame = +2
Query: 412 ALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLK-MEKEKEGFPITSLREI 470
++G S + + EGT+G V + KD + +ALK +K ++K +E + EI
Sbjct: 338 TMRGTSSTNDMKLCPHWGEGTFGKVVQCKDLLKGDDIALKIIKNVDKYREAAKL----EI 505
Query: 471 NTILKAQ----HPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGE-VKT 525
N + K + H + V+ + + I + + + ++ P E V+
Sbjct: 506 NVLEKLREKDPHAKHMCVQMLDWFDYHGHVCISFHMLGLSVFDFLKDNSYGAYPIEQVRH 685
Query: 526 LMIQLLRGVKHLHDNWILHRDLKTSNLLL 554
+ QL V LH+N + H DLK N+L
Sbjct: 686 ISYQLCYAVNFLHENQLTHTDLKPENILF 772
>00145
Length = 2325
Score = 30.4 bits (67), Expect = 2.6, Method: Composition-based stats.
Identities = 18/46 (39%), Positives = 24/46 (52%), Gaps = 1/46 (2%)
Frame = -1
Query: 692 PGRRISAEDGLKHEYFRETP-LPIDPSMFPTWPAKSEQQRVKRGTS 736
P RIS DG + RE+P LP D + P P + Q+ V R T+
Sbjct: 2313 PQHRISQSDGESVDVQRESPLLPRDGAAVPQRPGPAAQEGVSRQTA 2176
>15931
Length = 447
Score = 30.4 bits (67), Expect = 2.7, Method: Compositional matrix adjust.
Identities = 13/31 (41%), Positives = 19/31 (61%)
Frame = +1
Query: 679 QGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 709
Q FDLM+K L+Y R S ++H +FR+
Sbjct: 70 QLFDLMDKMLSYEVSTRYSLRQAMRHPFFRK 162
>38560
Length = 479
Score = 29.3 bits (64), Expect = 6.5, Method: Composition-based stats.
Identities = 12/30 (40%), Positives = 18/30 (60%)
Frame = -3
Query: 587 YRAPELLLGAKEYSTAVDMWSVGCIFGELL 616
Y APEL+ G + + D+WS+G + LL
Sbjct: 387 YAAPELISGLEYLGSEADIWSMGVLLYALL 298
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000367900 | hsapiens_gene_ensembl | PITSLRE
serine/threonine-protein kinase CDC2L2 (EC 2.7.11.22)
(Galactosyltransferase-associated protein kinase p58/GTA) (Cell
division cycle 2-like protein kinase 2) (CDK11).
[Source:Uniprot/SWISSPROT;Acc:Q9UQ88]
(783 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
29581 292 4e-84
01060 229 3e-60
01756 222 4e-58
14126 219 3e-57
04591 196 4e-50
32000 170 2e-42
01707 162 5e-40
04138 151 1e-36
01966 118 3e-28
23319 103 3e-22
00300 96 7e-20
03294 87 2e-17
18921 86 7e-17
06405 83 3e-16
13592 82 7e-16
12721 82 7e-16
01718 80 4e-15
09606 77 2e-14
03508 77 4e-14
20559 66 1e-13
12453 74 2e-13
14420 73 3e-13
15910 71 1e-12
26560 68 1e-11
19761 65 8e-11
18484 65 9e-11
21578 64 2e-10
27546 63 5e-10
13212 62 1e-09
30755 62 1e-09
14116 62 1e-09
03240 62 1e-09
13066 61 2e-09
28638 61 2e-09
26909 60 3e-09
19094 59 7e-09
21808 58 1e-08
24241 57 2e-08
11185 57 3e-08
19301 56 7e-08
27405 56 7e-08
18287 55 7e-08
28157 55 8e-08
31489 55 9e-08
07940 55 1e-07
26711 55 1e-07
17253 54 3e-07
04852 53 6e-07
00715 52 1e-06
18401 52 1e-06
21079 51 2e-06
12672 51 2e-06
16003 50 3e-06
00392 50 3e-06
12786 50 3e-06
17300 49 6e-06
31885 47 3e-05
11780 46 6e-05
05084 45 2e-04
20640 44 2e-04
07836 44 3e-04
17975 43 4e-04
21433 42 9e-04
07291 42 0.001
15549 40 0.005
18481 39 0.006
16708 39 0.007
14477 39 0.007
26009 32 0.007
37602 39 0.009
13078 38 0.014
02638 38 0.018
00486 35 0.099
36481 33 0.33
15931 30 2.6
00145 30 3.4
20152 30 4.1
38560 29 6.6
>29581
Length = 1278
Score = 292 bits (747), Expect(2) = 4e-84, Method: Compositional matrix adjust.
Identities = 133/261 (50%), Positives = 183/261 (70%)
Frame = -2
Query: 477 ILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLR 536
+L +H NIV ++E+VVG ++D +++VM Y E DL SL++ M PF +VK +++QLL+
Sbjct: 1193 LLNLRHQNIVQLQEVVVGKSLDSLFLVMEYCEQDLASLLDNMPAPFSESQVKCIVLQLLK 1014
Query: 537 GVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPEL 596
G+++LH+ +I+HRDLK SNLL++ G +K+ DFGLAR YG P K TP VVT WYRAPEL
Sbjct: 1013 GLRYLHEAFIIHRDLKVSNLLMTDKGCVKIADFGLARNYGKPQKPMTPKVVTLWYRAPEL 834
Query: 597 LLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSEL 656
L G+K +STA+DMWS GCI GELL KPL PG S++ QI + + LGTP++ IWPG+S+L
Sbjct: 833 LFGSKTHSTAIDMWSAGCILGELLGHKPLMPGRSDLQQIELIMELLGTPNDTIWPGFSQL 654
Query: 657 PVVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPL 716
P ++ T + PYNNLR F LS+ G L+N Y P +R +AED L+H YF+E P
Sbjct: 653 PAFEQFTLKKQPYNNLRHTF-PWLSESGIRLLNGLFMYHPQKRATAEDCLEHSYFKEQPY 477
Query: 717 PIDPSMFPTWPAKSEQQRVKR 737
P DP P++P Q R+KR
Sbjct: 476 PCDPEFMPSFP----QHRLKR 426
Score = 38.9 bits (89), Expect(2) = 4e-84, Method: Composition-based stats.
Identities = 17/35 (48%), Positives = 25/35 (71%)
Frame = -1
Query: 449 DEIVALKRLKMEKEKEGFPITSLREINTILKAQHP 483
+EIVALK+++M E+ G PI+ LREIN ++ P
Sbjct: 1278 NEIVALKKMRMTGERYGIPISGLREINIFAQSATP 1174
>01060
Length = 1800
Score = 229 bits (584), Expect = 3e-60, Method: Compositional matrix adjust.
Identities = 122/338 (36%), Positives = 204/338 (60%), Gaps = 2/338 (0%)
Frame = +1
Query: 401 LLPIELKQELPKYLPALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKME 460
LL + +K+ + + AL + +FQ +I EGTYGVVY+ + + T +A+K++++
Sbjct: 22 LLKLNIKRLMMDFETALS---DLTDFQ---KIGEGTYGVVYKCRHRATGRKLAMKKIRLR 183
Query: 461 KEKEGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQ 520
++G P +++REI + + +H NIV + ++++ +++++V ++ DLK ++ +
Sbjct: 184 GSEDGVPSSAIREIAMLRELRHTNIVCLEDVIMED--ERLFLVFEFLSMDLKMYIDKFPE 357
Query: 521 PFLPGE--VKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSP 578
+ VK+ + Q++ G+ H I+HRDLK NLL++H G +K+ DFG+AR + P
Sbjct: 358 GVVLDRRLVKSYVFQIVTGIXFCHQRRIVHRDLKPQNLLINHTGAIKIADFGMARTFALP 537
Query: 579 LKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKV 638
++AYT VVT WYRAPE+L+GA +YST VD+WS+G IF ++L + P+F G+SEIDQ+ K+
Sbjct: 538 VRAYTHEVVTLWYRAPEILMGASKYSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKI 717
Query: 639 FKELGTPSEKIWPGYSELPVVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGR 698
F+ +GTP+E+ WP + +LP M F L + L S G DL+ + L P +
Sbjct: 718 FRIIGTPTEQTWPEFHKLPAFNGM-FPLWKEGKLSETLTDLDS-LGLDLIERTLKCDPAQ 891
Query: 699 RISAEDGLKHEYFRETPLPIDPSMFPTWPAKSEQQRVK 736
RIS + L+H YF + P P+ P S R+K
Sbjct: 892 RISCKKMLQHAYFLNVDTSVKPVDVPS-PEHS*STRLK 1002
>01756
Length = 1858
Score = 222 bits (566), Expect = 4e-58, Method: Compositional matrix adjust.
Identities = 117/309 (37%), Positives = 187/309 (60%), Gaps = 10/309 (3%)
Frame = -3
Query: 420 CRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILK 479
C +++ L +I +GT+G V++A+ KKT ++VA+K++ M+ EKEGFPIT+LREI +
Sbjct: 1754 CDEDAKYEKLAKIGQGTFGEVFKARCKKTKQVVAMKKVLMDNEKEGFPITALREIKILQL 1575
Query: 480 AQHPNIVTVREIV----VGSNMDK--IYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQ 533
H N+V + EI +N K Y+V + EHDL L+ M F E+K +M Q
Sbjct: 1574 LNHENVVDLIEICSTKATSANRYKSMFYLVFEFCEHDLAGLLSNMSVVFNLPEIKEVMKQ 1395
Query: 534 LLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKA---YTPVVVTQW 590
L+ G+ ++H N ILHRD+K +N+L++ G+LK+ DFGLAR + L+ YT VVT W
Sbjct: 1394 LMNGLYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLW 1215
Query: 591 YRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIW 650
YR PELLLG + YSTA+D W GCI E+ T+ P+ G +E +Q+ + + G+ + ++W
Sbjct: 1214 YRPPELLLGDRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQNQLTLITQLCGSITPEVW 1035
Query: 651 PGYSELPVVKKMTFSEHPYNNLRKRFGALLSDQ-GFDLMNKFLTYFPGRRISAEDGLKHE 709
PG L + + + +++R + D DL++K L PG+R+++++ L H+
Sbjct: 1034 PGVERLELYNSLDLPQGNKRKVKERLRYYIKDAYALDLLDKLLALDPGKRVNSDEALSHD 855
Query: 710 YFRETPLPI 718
+F P P+
Sbjct: 854 FFWMDPEPL 828
>14126
Length = 1265
Score = 219 bits (558), Expect = 3e-57, Method: Compositional matrix adjust.
Identities = 125/299 (41%), Positives = 182/299 (60%), Gaps = 9/299 (3%)
Frame = +3
Query: 424 EEFQCLNRIEEGTYGVVYRAKD-KKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQ- 481
++++ + I G YG VY+A+D + E VA+KR+++ +EG P+ ++REI+ + + +
Sbjct: 189 QKYEEVAVIGNGAYGTVYKARDLRNQGEFVAMKRIRLNNTEEGMPMMAIREISMLKQLEQ 368
Query: 482 --HPNIVTVREIVVGSNMDK---IYIVMNYVEHDLKSLMETMKQPFL-PGEVKTLMIQLL 535
HPN+V + ++ + D+ + +V Y+EHDL + + P L P +K LM+QLL
Sbjct: 369 YEHPNVVRLLDVSHNTITDREIRLNLVFEYIEHDLATYLAKCPSPGLGPDRIKDLMLQLL 548
Query: 536 RGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPE 595
GV LH N I+HRDLK NLL+S G LK+ DFGLAR Y + A T VVVT WYR+PE
Sbjct: 549 NGVDFLHSNRIVHRDLKPQNLLISKDGRLKLADFGLARIYSFHM-ALTTVVVTLWYRSPE 725
Query: 596 LLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWP-GYS 654
+L+ A EY T+VD+WS GCIF EL T++ LF G+SE DQ+ K+F+ +G P WP G S
Sbjct: 726 VLMQA-EYGTSVDIWSCGCIFAELFTRRALFKGSSEFDQLKKIFEVIGLPPAGDWPEGVS 902
Query: 655 ELPVVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 713
V + +F P L+ + Q DLM K L + GRRIS+ + L H Y R+
Sbjct: 903 ----VHRNSFRPTPPVPLQTLVPE-MDPQAKDLMEKMLVFKSGRRISSRESLLHPYLRD 1064
>04591
Length = 1117
Score = 196 bits (497), Expect = 4e-50, Method: Compositional matrix adjust.
Identities = 102/267 (38%), Positives = 161/267 (60%), Gaps = 7/267 (2%)
Frame = -2
Query: 463 KEGFPITSLREINTILKAQHPNIVTVREIV------VGSNMDKIYIVMNYVEHDLKSLME 516
KEGFPIT+LREI + + +H N+V ++EI Y++ Y ++DL L+
Sbjct: 1101 KEGFPITALREIKILQQLEHENVVQLQEICHTQAGPYNRYKSTFYLIFEYCDYDLAGLLN 922
Query: 517 TMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYG 576
++ F + K LM QLL G+ ++H ILHRD+K +N+LL+ G+LK+ DFGL+R +
Sbjct: 921 NLRVKFSLADKKNLMSQLLNGLFYIHTKQILHRDIKAANILLTRDGVLKLADFGLSRPWV 742
Query: 577 SPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQIN 636
K T VVT WYR PELLLG +EY +DMW VGCI E+ ++KPL G SE Q++
Sbjct: 741 KS-KRLTNRVVTLWYRPPELLLGEREYGPEIDMWGVGCIMAEMWSRKPLMQGRSEQHQLS 565
Query: 637 KVFKELGTPSEKIWPGYSELPVVKKMTFSEHPYNNLRKRFGALLSD-QGFDLMNKFLTYF 695
+ G+ + ++WPG ++L + K+ + +++R LL + +G +L++ FL
Sbjct: 564 LITDLCGSLNAEVWPGVTKLELYGKLDLPQGKPRKVKERMLDLLKNKEGAELIDIFLRLD 385
Query: 696 PGRRISAEDGLKHEYFRETPLPIDPSM 722
PG+R++ ++ L H++F PLP PS+
Sbjct: 384 PGQRMNCDNALSHDFFWVDPLP-SPSL 307
>32000
Length = 644
Score = 170 bits (430), Expect = 2e-42, Method: Compositional matrix adjust.
Identities = 79/150 (52%), Positives = 106/150 (70%)
Frame = -1
Query: 564 LKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQK 623
+K+ DFGLAR +G P++ YT V+T WYRAPE+LLG + YS VD+WS+GCIF E++T++
Sbjct: 572 MKIADFGLARVFGLPVRTYTHEVITLWYRAPEILLGCRFYSVPVDIWSLGCIFVEMMTRR 393
Query: 624 PLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKMTFSEHPYNNLRKRFGALLSDQ 683
LFPG+SEIDQ+ ++F+ LGTP EK+WPG S+LP K TF + P NL LS
Sbjct: 392 ALFPGDSEIDQLYRIFRTLGTPDEKVWPGVSKLPDYKP-TFPKWPLKNLETVVS--LSKV 222
Query: 684 GFDLMNKFLTYFPGRRISAEDGLKHEYFRE 713
G DL+ + LTY P RRISA ++H YF +
Sbjct: 221 GLDLLKRMLTYNPNRRISARSAMRHPYFND 132
>01707
Length = 757
Score = 162 bits (410), Expect = 5e-40, Method: Compositional matrix adjust.
Identities = 81/221 (36%), Positives = 138/221 (62%)
Frame = +1
Query: 423 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 482
+E+++ + +I EG+YGVV++ ++K+T ++VA+K+ ++ ++REI + + +H
Sbjct: 61 MEKYEKIGKIGEGSYGVVFKCRNKETSQLVAIKKFVESEDDPLIKKIAMREIRMLKQLKH 240
Query: 483 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLH 542
PN+V R I V ++++V +YV+H L + ++ + VK ++ Q L V H
Sbjct: 241 PNLV--RLIEVFRRKKRLHLVFDYVDHTLLNELDRYPRGLPEPMVKRIIYQTLLAVNFCH 414
Query: 543 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKE 602
+HRD+K N+L++ G +K+ DFG AR P YT V T+WYRAPELL+G +
Sbjct: 415 QYNTIHRDVKPENILITRQGQVKLCDFGFARILTGPGDEYTDYVATRWYRAPELLVGDTQ 594
Query: 603 YSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELG 643
Y VD+W++GC+F ELLT + L+PG S++DQ++ + K LG
Sbjct: 595 YGPPVDVWAIGCVFAELLTGQALWPGRSDVDQLHLIRKTLG 717
>04138
Length = 800
Score = 151 bits (381), Expect = 1e-36, Method: Compositional matrix adjust.
Identities = 72/178 (40%), Positives = 111/178 (62%), Gaps = 6/178 (3%)
Frame = +1
Query: 540 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKA---YTPVVVTQWYRAPEL 596
++H N ILHRD+K +N+L++ G+LK+ DFGLAR + L+ YT VVT WYR PEL
Sbjct: 58 YIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRPPEL 237
Query: 597 LLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSEL 656
LLG + YSTA+D W GCI E+ T+ P+ G +E +Q+ + + G+ + ++WPG ++L
Sbjct: 238 LLGDRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQNQLTLITQLCGSITPEVWPGVTQL 417
Query: 657 PVVKKM--TFSEHPYNNLRKRFGALLSD-QGFDLMNKFLTYFPGRRISAEDGLKHEYF 711
+ ++ + N +R RF +L D G DL + L P +RISA++ L H++F
Sbjct: 418 SMYHQIKGALAAGRKNIIRDRFARILKDPYGLDLFERLLKMDPSQRISADEALNHDFF 591
>01966
Length = 1735
Score = 118 bits (296), Expect(2) = 3e-28, Method: Compositional matrix adjust.
Identities = 55/175 (31%), Positives = 107/175 (61%), Gaps = 2/175 (1%)
Frame = -1
Query: 443 AKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYI 502
+ + T +A+K++++ ++G P +++REI + + +H NIV + ++++ +++++
Sbjct: 1654 CRHRATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTNIVCLEDVIMED--ERLFL 1481
Query: 503 VMNYVEHDLKSLMETMKQPFLPGE--VKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSH 560
V ++ DLK ++ + + VK+ + Q++ G+ H I+HRDLK NLL++H
Sbjct: 1480 VFEFLSMDLKMYIDKFPEGVVLDRRLVKSYVFQIVTGINFCHQRRIVHRDLKPQNLLINH 1301
Query: 561 AGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCI 615
G +K+ DFG+AR + P++AYT VVT WYRAPE+L+G + + W+ G +
Sbjct: 1300 TGAIKIADFGMARTFALPVRAYTHEVVTLWYRAPEILMGPQ---STPPXWTCGAL 1145
Score = 25.4 bits (54), Expect(2) = 3e-28, Method: Composition-based stats.
Identities = 10/13 (76%), Positives = 12/13 (92%)
Frame = -2
Query: 429 LNRIEEGTYGVVY 441
L++I EGTYGVVY
Sbjct: 1695 LSKIGEGTYGVVY 1657
Score = 97.4 bits (241), Expect = 2e-20, Method: Compositional matrix adjust.
Identities = 54/138 (39%), Positives = 80/138 (57%)
Frame = -3
Query: 599 GAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPV 658
GA +YST VD+WS+G IF ++L + P+F G+SEIDQ+ K+F+ +GTP+E+ WP + +LP
Sbjct: 1187 GASKYSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKLPA 1008
Query: 659 VKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPI 718
M F L + L S G DL+ + L P +RIS + L+H YF +
Sbjct: 1007 FNGM-FPLWKEGKLSETLTDLDS-LGLDLIERTLKCDPAQRISCKKMLQHAYFLNVDTSV 834
Query: 719 DPSMFPTWPAKSEQQRVK 736
P P+ P +S R+K
Sbjct: 833 KPVDVPS-PEQS*STRLK 783
>23319
Length = 2235
Score = 103 bits (256), Expect = 3e-22, Method: Compositional matrix adjust.
Identities = 50/117 (42%), Positives = 72/117 (61%), Gaps = 1/117 (0%)
Frame = +3
Query: 600 AKEYSTAVDMWSVGCIFGELLTQ-KPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPV 658
AK YST++DMWS GCIF EL +PLFPGN + DQ+ ++FK LGTP+E WPG ++LP
Sbjct: 18 AKMYSTSIDMWSAGCIFAELANAGRPLFPGNDDDDQLKRIFKLLGTPTEDQWPGMTQLPN 197
Query: 659 VKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETP 715
+ F + ++ L+ +G DL+ L P R+SA++ L+H YF + P
Sbjct: 198 YR--MFPMYHVTTTWQQVVPKLNSKGRDLLQCLLVCCPSDRMSADEALQHPYFADLP 362
>00300
Length = 2318
Score = 95.5 bits (236), Expect = 7e-20, Method: Compositional matrix adjust.
Identities = 66/207 (31%), Positives = 108/207 (52%), Gaps = 13/207 (6%)
Frame = -1
Query: 430 NRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKA----QHPNI 485
N+I EG +G VY A + T E++ALK +K + + LRE+ +K QH N+
Sbjct: 1640 NKIGEGQFGKVYTAVNMSTGELMALKEMKFQPND----LQQLREMCDEIKIFEGIQHENL 1473
Query: 486 VTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNW 545
V + V + D++ + M Y D ++ E K ++ +++ V HLH+N
Sbjct: 1472 VKYYGVEV--HKDEMLMFMEYC--DTGTIEEAAKMGLPEYLIRRYTREIVLAVNHLHENS 1305
Query: 546 ILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTP-------VVVTQWYRAPELLL 598
I+HRD+K +N+ L+ G +K+GDFG + + LK++T +V T Y APE+
Sbjct: 1304 IVHRDIKGANIFLTSNGHVKLGDFGCSVK----LKSHTTMPGEFHNLVGTTAYMAPEVFT 1137
Query: 599 GAKE--YSTAVDMWSVGCIFGELLTQK 623
+ Y A D+WS+GC+ E+ T K
Sbjct: 1136 QNDQGGYGRAADIWSLGCVVIEMATGK 1056
>03294
Length = 1684
Score = 87.4 bits (215), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 49/130 (37%), Positives = 73/130 (56%)
Frame = -1
Query: 607 VDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKMTFSE 666
VD+WS+G IF ++L + P+F G+SEIDQ+ K+F+ +GTP+E+ WP + +LP M F
Sbjct: 1672 VDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKLPAFNGM-FPL 1496
Query: 667 HPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSMFPTW 726
L + L S G DL+ + L P +RIS + L+H YF + P P+
Sbjct: 1495 WKEGKLSETLTDLDS-LGLDLIERTLKCDPAQRISCKKMLQHAYFLNVDTSVKPVDVPS- 1322
Query: 727 PAKSEQQRVK 736
P S R+K
Sbjct: 1321 PEHS*STRLK 1292
>18921
Length = 697
Score = 85.5 bits (210), Expect = 7e-17, Method: Compositional matrix adjust.
Identities = 57/205 (27%), Positives = 109/205 (53%), Gaps = 6/205 (2%)
Frame = +2
Query: 426 FQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNI 485
F L ++ EG+YG V+++ K+T +++A+K++ ++ + + ++EI+ + + I
Sbjct: 35 FDILGKLGEGSYGSVFKSLHKETGQVLAIKQVPVDTDLQEI----IKEISIMQQCDSKYI 202
Query: 486 VTVREIVVGS---NMDKIYIVMNYV-EHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHL 541
V GS N D ++IVM Y + +M + + E+ T++ L+G+ +L
Sbjct: 203 VKYY----GSYFKNTD-LWIVMEYCGAGSVSDIMRLRNKTLVEREIATILYYTLKGLXYL 367
Query: 542 HDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELL--LG 599
H +HRD+K N+LL++ G K+ DFG+A + + V+ T ++ APE++ +G
Sbjct: 368 HSRRKIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTPYWMAPEVIQEIG 547
Query: 600 AKEYSTAVDMWSVGCIFGELLTQKP 624
Y D+WS+G E+ KP
Sbjct: 548 ---YDCVADIWSLGITALEMAEGKP 613
>06405
Length = 1965
Score = 83.2 bits (204), Expect = 3e-16, Method: Compositional matrix adjust.
Identities = 63/205 (30%), Positives = 102/205 (49%), Gaps = 8/205 (3%)
Frame = +1
Query: 425 EFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILK-AQHP 483
E +R+ G YG VY A K+ ++IVA+K LK ++ + E I+K +HP
Sbjct: 262 EIAMKHRLGGGQYGDVYEAMWKRYNKIVAVKTLK----EDTMALNDFLEEAAIMKEMKHP 429
Query: 484 NIVTVREIVVGSNMDKIYIVMNYVEHD--LKSLMETMKQPFLPGEVKTLMIQLLRGVKHL 541
N+V + + V + YIV ++ H L L + ++ P + + Q+ G+ +L
Sbjct: 430 NLVQL--LGVCTREPPFYIVTEFMPHGNLLDYLRSSTREENGPTALMYMATQIASGMAYL 603
Query: 542 HDNWILHRDLKTSNLLLSHAGILKVGDFGLAR-----EYGSPLKAYTPVVVTQWYRAPEL 596
+HRDL N L++ + ++KV DFGLAR Y + + A P+ +W APE
Sbjct: 604 ETKNFIHRDLAARNCLVADSNMVKVADFGLARLMKDDTYTAHIGAKFPI---KW-TAPE- 768
Query: 597 LLGAKEYSTAVDMWSVGCIFGELLT 621
L +ST D+W+ G + EL T
Sbjct: 769 GLAFNRFSTRSDIWAFGVLLWELAT 843
>13592
Length = 980
Score = 82.4 bits (202), Expect = 7e-16, Method: Compositional matrix adjust.
Identities = 80/295 (27%), Positives = 138/295 (46%), Gaps = 13/295 (4%)
Frame = +2
Query: 431 RIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVRE 490
+I +G +G VY A + T E++A+K + ++ + E+ + +H N+V
Sbjct: 5 KIGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETRALKNVAEELKILEGIKHKNLVRYYG 184
Query: 491 IVVGSNMDKIYIVMNYV-EHDLKSLMETMKQPFLPGEV-KTLMIQLLRGVKHLHDNWILH 548
I V + +++ I M E L+SL+E LP + + QLL GV LH + I+H
Sbjct: 185 IEV--HREELLIFMELCSEGTLESLVELTGG--LPEALSRRFTAQLLSGVAELHKHGIVH 352
Query: 549 RDLKTSNL-LLSHAGILKVGDFGLAREYGSPLKAYTPV-------VVTQWYRAPELL--L 598
RD+KT+N+ L+ + LK+GDFG A + ++A+T V V TQ Y APE+
Sbjct: 353 RDIKTANIFLVDGSNSLKLGDFGSAVK----IQAHTTVPGELQGYVGTQAYMAPEVFTKT 520
Query: 599 GAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGY-SELP 657
+ + D+WSVGC+ E+ + K + W + S
Sbjct: 521 NSDGHGRLADIWSVGCVVVEMASGK------------------------RPWAQFDSNFQ 628
Query: 658 VVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFR 712
++ K+ E P + LS +G D ++ L + P +R+SA + L+ + +
Sbjct: 629 IMFKVGMGEKP------QAPESLSQEGHDFIDHCLQHDPKQRLSAIELLEQNFCK 775
>12721
Length = 821
Score = 82.4 bits (202), Expect = 7e-16, Method: Compositional matrix adjust.
Identities = 53/196 (27%), Positives = 106/196 (54%)
Frame = +1
Query: 431 RIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVRE 490
+I EG+ G+V A + ++ A+K++ + K++ + E+ + HPNIV +
Sbjct: 109 KIGEGSTGIVCIATSRDGRQM-AVKKMDLRKQQRRELL--FNEVVVMRDYHHPNIVEMYN 279
Query: 491 IVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRD 550
+ + D++++VM ++E + + T + ++ T+ L+ + LH N ++HRD
Sbjct: 280 SYLVN--DELWVVMEFMEGGALTDIVTNNR-MDEVQIATVCRACLKALAFLHANGVIHRD 450
Query: 551 LKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMW 610
+K+ ++LLSH G +K+ DFG + L+ +V T ++ APE ++ Y VD+W
Sbjct: 451 IKSDSILLSHDGKVKLXDFGFCAQVTQDLQKRKSLVGTPYWMAPE-VISRLPYGPEVDIW 627
Query: 611 SVGCIFGELLTQKPLF 626
S+G + E++ +P F
Sbjct: 628 SLGIMVMEMIDAEPPF 675
>01718
Length = 959
Score = 79.7 bits (195), Expect = 4e-15, Method: Compositional matrix adjust.
Identities = 60/218 (27%), Positives = 107/218 (49%), Gaps = 6/218 (2%)
Frame = +3
Query: 416 ALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREIN 475
A+ +++F C +I G + V++ + T +++ALK M + LRE+
Sbjct: 126 AVSALTRLDDFIC-EKIGAGFFSEVFKVTHRITGQVMALKMNTMTSNRHNM----LREVQ 290
Query: 476 TILKAQHPNIVTVREIVVGSNMDKIYIVMNYV-EHDLKSLMETMKQPFLPGEVKTLMIQL 534
+ + QH NI+ + V +++ + Y+ +L+ L+E + + L + L
Sbjct: 291 LLNRLQHANILRFMGVCVHEG--QLHALTEYIPSGNLEQLLEKKDEELPWTQRIQLTLGL 464
Query: 535 LRGVKHLHDNWILHRDLKTSNLLL----SHAGILKVGDFGLAREYGSPL-KAYTPVVVTQ 589
RG+ +LH +HRDL + N+L+ +H + DFGLA + PL K P V +
Sbjct: 465 ARGLDYLHSTRFIHRDLTSKNILIRREDNHGYHAVIADFGLATKIPDPLDKEKLPTVGSP 644
Query: 590 WYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFP 627
++ APE+L G Y+ D++SVG I E+ + P P
Sbjct: 645 YWMAPEVLNG-HFYNERADLFSVGIIMCEITARIPADP 755
>09606
Length = 1300
Score = 77.4 bits (189), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 82/314 (26%), Positives = 134/314 (42%), Gaps = 24/314 (7%)
Frame = -3
Query: 423 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 482
+E F + +G + ++Y+ + K T VA+ + EK K ++R + I H
Sbjct: 1118 MENFVLYEELGKGEHSIIYKGRRKGTINFVAIHCI--EKCKRPEVTNTVRMTHDI---SH 954
Query: 483 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPF-LP-GEVKTLMIQLLRGVKH 540
PN+V E SN +++V+ SL + + Q LP ++ I L+ G+ +
Sbjct: 953 PNVVQFHEWYETSN--HLWLVVELCTGG--SLADILAQDHHLPETSIRDFGIHLVTGLHY 786
Query: 541 LHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAY------------------ 582
+H IL DL+ S +LL +G+LK DFGL++ G L+
Sbjct: 785 IHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQWNIQSAEE 606
Query: 583 ----TPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKV 638
P + Y APE+ GA E S D+W++GC+F E+ + P F G + +KV
Sbjct: 605 MMKQVPTSGSPTYMAPEVFQGA-EPSIMSDLWALGCVFYEMFSGHPPFLGETYDITKDKV 429
Query: 639 FKELGTPSEKIWPGYSELPVVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGR 698
K +P LP VK S P S + +L+ L R
Sbjct: 428 LN-------KEFP----LPKVKGSRLSAKP------------SPEFLNLLESLLQKDSTR 318
Query: 699 RISAEDGLKHEYFR 712
R+S +KH +++
Sbjct: 317 RLSWASLVKHAFWQ 276
>03508
Length = 1463
Score = 76.6 bits (187), Expect = 4e-14, Method: Compositional matrix adjust.
Identities = 39/122 (31%), Positives = 72/122 (59%), Gaps = 2/122 (1%)
Frame = +1
Query: 508 EHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGI-LKV 566
EH + + + Q F +++ + +L++ + H I+HRD+K N+++ H L++
Sbjct: 820 EHVNNTDFKQLYQTFTDYDIRFYLYELMKALDFCHSMGIMHRDVKPHNVMIDHENKKLRL 999
Query: 567 GDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQK-PL 625
D+GLA E+ P Y V +++++ PELLL + Y ++DMWS+GC+F ++ +K PL
Sbjct: 1000IDWGLA-EFYHPGMEYNVRVASRYFKGPELLLDYQMYDYSLDMWSLGCMFASMIFRKEPL 1176
Query: 626 FP 627
P
Sbjct: 1177LP 1182
Score = 35.0 bits (79), Expect = 0.12, Method: Compositional matrix adjust.
Identities = 27/114 (23%), Positives = 51/114 (44%), Gaps = 12/114 (10%)
Frame = +2
Query: 610 WSVG----CIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKMTFS 665
W+ G C+ + P F G+ DQ+ ++ K LGT + ++ + + F+
Sbjct: 1118 WTCGVWAACLPA*SSGKSPFFHGHDNYDQLVRIAKVLGT--DDLYGYIEKYQIDLDPRFN 1291
Query: 666 EHPYNNLRKRF--------GALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYF 711
+ + RKR+ L+S + D ++K L Y R++A + + H YF
Sbjct: 1292 DILGRHSRKRWERFVHSENQHLISPEALDFLDKLLRYDHNERLTAREAMDHPYF 1453
>20559
Length = 430
Score = 66.2 bits (160), Expect(2) = 1e-13, Method: Compositional matrix adjust.
Identities = 31/82 (37%), Positives = 58/82 (70%)
Frame = -2
Query: 411 PKYLPALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITS 470
P +L + +++++ L +I EGTYG V++AK+++T EIVALKR++++ + EG P ++
Sbjct: 414 PTHLHSF*LKHKMQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSA 235
Query: 471 LREINTILKAQHPNIVTVREIV 492
LREI + + +H NIV + +++
Sbjct: 234 LREICLLKELKHRNIVRLHDVL 169
Score = 29.3 bits (64), Expect(2) = 1e-13, Method: Composition-based stats.
Identities = 14/36 (38%), Positives = 19/36 (52%)
Frame = -3
Query: 506 YVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHL 541
Y + DLK +T P VK+ + QLLRG+ L
Sbjct: 134 YCDQDLKKYFDTCNGEIDPDTVKSFLHQLLRGLGFL 27
>12453
Length = 680
Score = 74.3 bits (181), Expect = 2e-13, Method: Composition-based stats.
Identities = 41/100 (41%), Positives = 55/100 (55%)
Frame = +3
Query: 612 VGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKMTFSEHPYNN 671
VGCIF E+ +PLFPG++ D+++ +FK LGTP+E P S P + +
Sbjct: 6 VGCIFYEMACGRPLFPGSTVEDELHLIFKTLGTPTEDSLPSISRNPDFLALNLPHYQGEA 185
Query: 672 LRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYF 711
L L SD G DL+ KFL Y R+SA D LKH +F
Sbjct: 186 LITIAPRLDSD-GLDLLAKFLKYNAKIRVSAADSLKHSFF 302
>14420
Length = 528
Score = 73.2 bits (178), Expect = 3e-13, Method: Compositional matrix adjust.
Identities = 44/156 (28%), Positives = 90/156 (57%), Gaps = 2/156 (1%)
Frame = +2
Query: 471 LREINTILKAQHPNIVT-VREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLP-GEVK 528
+ EI + + Q+PNIV + +VG +++++VM ++ SL + + + + G++
Sbjct: 44 INEILVMRENQNPNIVNYLDSYLVG---EELWVVMEFLAGG--SLTDVVTETCMDEGQIA 208
Query: 529 TLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVT 588
+ + L+ ++ LH+N ++HRD+K+ N+LL G +K+ DFG + + +V T
Sbjct: 209 AVCRECLQALEFLHENQVIHRDIKSDNILLGMDGSVKLTDFGFCAQLSPEQSKRSTMVGT 388
Query: 589 QWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKP 624
++ APE ++ K+Y VD+WS+G + E++ +P
Sbjct: 389 PYWMAPE-VVTRKQYGPTVDIWSLGVMCIEMIEGEP 493
>15910
Length = 1361
Score = 71.2 bits (173), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 49/125 (39%), Positives = 67/125 (53%), Gaps = 3/125 (2%)
Frame = +2
Query: 534 LLRGVKHLHDNWILHRDLKTSNLL---LSHAGILKVGDFGLAREYGSPLKAYTPVVVTQW 590
+L GV+++H N ++HRDLK NLL ++ LK+ DFGL+R P + V T
Sbjct: 491 ILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLADFGLSRII-EPEVQMSTVCGTPG 667
Query: 591 YRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIW 650
Y APE+L G K Y+ +VDMWSVG I LL F +E + K+ K E+ W
Sbjct: 668 YCAPEVLKGDK-YTPSVDMWSVGVIAYILLCGYEPFFAENEFEMYRKIIKGEYKFDEEYW 844
Query: 651 PGYSE 655
SE
Sbjct: 845 SEISE 859
>26560
Length = 398
Score = 68.2 bits (165), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 37/119 (31%), Positives = 66/119 (55%), Gaps = 4/119 (3%)
Frame = -1
Query: 522 FLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKA 581
F EV+ +++ G++H+H ++++RDLK +N+LL G +++ D GLA ++ K
Sbjct: 365 FTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGLACDFSK--KR 192
Query: 582 YTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLF----PGNSEIDQIN 636
V T Y APE+L+ + Y ++ D +S GC+ +LL F G + ID++
Sbjct: 191 PHASVGTHGYMAPEVLMKGQSYDSSADWFSFGCMLYKLLKGHSPFRQHNQGQARIDRMT 15
>19761
Length = 473
Score = 65.5 bits (158), Expect = 8e-11, Method: Compositional matrix adjust.
Identities = 36/104 (34%), Positives = 60/104 (57%)
Frame = -3
Query: 540 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLG 599
H H ILHRDLK N+ ++ G +++GD GLAR+ P T V T Y +PE +L
Sbjct: 372 HTHTPVILHRDLKPQNIYVTEKGDVRLGDLGLARKLTGPADFATSQVGTIMYLSPE-ILS 196
Query: 600 AKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELG 643
+ Y++ D+WS+GC+F ++ +K G+ E+ + + + +G
Sbjct: 195 QQPYNSKSDIWSLGCVFYDITGKK----GSDEMGVMFLLVQVMG 76
>18484
Length = 635
Score = 65.5 bits (158), Expect = 9e-11, Method: Compositional matrix adjust.
Identities = 35/106 (33%), Positives = 58/106 (54%)
Frame = +1
Query: 533 QLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYR 592
++ G+ LHD I++RDLK N++L G +K+ DFG+ +E + T Y
Sbjct: 67 EIAVGLFFLHDQGIIYRDLKLDNVMLDSEGHIKIADFGMCKEGMTGDATTRTFCGTPDYI 246
Query: 593 APELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKV 638
APE++L + YS +VD W+ G + E+L +P F G E + + +
Sbjct: 247 APEIVL-YQPYSKSVDWWAYGVLLFEMLAGQPPFDGEDEDELFSSI 381
>21578
Length = 524
Score = 64.3 bits (155), Expect = 2e-10, Method: Composition-based stats.
Identities = 26/33 (78%), Positives = 31/33 (93%)
Frame = +2
Query: 406 LKQELPKYLPALQGCRSVEEFQCLNRIEEGTYG 438
LK++LP YLPA+QGCR+VEEF C+NRIEEGTYG
Sbjct: 425 LKEDLPVYLPAIQGCRNVEEFHCMNRIEEGTYG 523
>27546
Length = 426
Score = 62.8 bits (151), Expect = 5e-10, Method: Composition-based stats.
Identities = 38/113 (33%), Positives = 60/113 (53%), Gaps = 2/113 (1%)
Frame = -1
Query: 463 KEGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQ-- 520
K+ FP RE+ + + HPNI+ + I+ KI+I M Y E ++ +K+
Sbjct: 348 KKFFP----RELEILTRLDHPNIIQIHSIL--QRGPKIFIFMRYAEKG--DMLSHIKKTG 193
Query: 521 PFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAR 573
P + K Q+ + +++LH + I HRDLK N+LLS +K+ DFG AR
Sbjct: 192 PIDEAQTKVWFFQMAKALQYLHSHDIAHRDLKCENILLSKRLNVKIADFGFAR 34
>13212
Length = 1067
Score = 61.6 bits (148), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 46/206 (22%), Positives = 93/206 (45%), Gaps = 4/206 (1%)
Frame = -1
Query: 511 LKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFG 570
L S+M +++P ++ + ++ + LH + ++HRD+K N+LL+ G +K+ DFG
Sbjct: 1022 LDSIMVDLEKPMTEAQICYVCHEMCMALDFLHRHHVIHRDIKAGNVLLTIDGEVKLADFG 843
Query: 571 LAREYGSPLKAYTPVVVTQWYRAPELLLGA----KEYSTAVDMWSVGCIFGELLTQKPLF 626
++ + + + T ++ APE++L Y D+WS+G E
Sbjct: 842 VSAKNTQTQQKRDTFIGTPYWMAPEVVLCETLKDTPYDFKADIWSLGVTLIE-------- 687
Query: 627 PGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKMTFSEHPYNNLRKRFGALLSDQGFD 686
F ++ P++++ P + V+ K+ S+ P K++ L D
Sbjct: 686 ------------FAQIEPPNKEMHP----MRVLIKIHKSDPPTLEKPKKWTKLFK----D 567
Query: 687 LMNKFLTYFPGRRISAEDGLKHEYFR 712
+ K L P R +A + L+H + +
Sbjct: 566 FIAKCLVKDPNLRPTAAELLEHPFMK 489
>30755
Length = 1137
Score = 61.6 bits (148), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 35/94 (37%), Positives = 51/94 (54%), Gaps = 3/94 (3%)
Frame = +2
Query: 533 QLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLARE---YGSPLKAYTPVVVTQ 589
+++ + +LH I++RDLK NLLL G +KV DFGL +E YG K + T
Sbjct: 56 EIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCKEDITYGRTTKTFCG---TP 226
Query: 590 WYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQK 623
Y APE +L +Y AVD W G + E++ +
Sbjct: 227 EYLAPE-VLDDNDYGRAVDWWGTGVVMYEMICGR 325
>14116
Length = 1017
Score = 61.6 bits (148), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 61/205 (29%), Positives = 99/205 (48%), Gaps = 14/205 (6%)
Frame = -1
Query: 432 IEEGTYGVVYRA----KDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVT 487
I +G +G V R ++K D +VA+K L +E + L+E + H N++T
Sbjct: 612 IGKGNFGCVKRGFLTLPEQKGDILVAVKTLHNNNPREIELQSFLQEALIMKDFHHSNVLT 433
Query: 488 VREIVVGSNMDKI-YIVMNYVEHD--LKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDN 544
+ I + N+D + +V+ +++H L + + QP + ++ + + RG+ +L
Sbjct: 432 LIGICL--NLDDMPLVVLPFMKHGDLLTYIRDDQHQPTIK-DLIMYGVDIARGMDYLAGL 262
Query: 545 WILHRDLKTSNLLLSHAGILKVGDFGLAR-----EYGSP--LKAYTPVVVTQWYRAPELL 597
+HRDL N +L +KV DFGLAR EY S KA PV +W L
Sbjct: 261 KFVHRDLAARNCMLDEDFHVKVADFGLARDIYEKEYYSSENKKAKLPV---KWMALESLE 91
Query: 598 LGAKEYSTAVDMWSVGCIFGELLTQ 622
G Y + D+WS G + ELLT+
Sbjct: 90 KG--NYDSKTDVWSYGVVLWELLTR 22
>03240
Length = 1683
Score = 61.6 bits (148), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 62/262 (23%), Positives = 105/262 (40%), Gaps = 48/262 (18%)
Frame = -3
Query: 426 FQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNI 485
F+ + + G +G V + T + A+K L+ + + ++ IL A+ N
Sbjct: 1285 FEKIKTLGVGAFGEVSLCRKNDTGMLYAMKTLRKSDVLKRNQVAHVKAERDIL-AEADNE 1109
Query: 486 VTVREIVVGSNMDKIYIVMNYV-EHDLKSL---METMKQPFLPGEVKTLMIQLLRGVKHL 541
V+ + + +Y VM+YV DL L ME + +P + + +L++ ++ +
Sbjct: 1108 WVVKLYYSFQDHNYLYFVMDYVPGGDLMGLLIRMEILDEPL----ARFYVAELVQAIESV 941
Query: 542 HDNWILHRDLKTSNLLLSHAGILKVGDFGL-------------------AREYGSPLKAY 582
H +HRD+K N+L+ G +K+ DFGL AR+ +K
Sbjct: 940 HRMGFIHRDIKPDNILIDRNGHIKLTDFGLCTGFRWTHNSKYYQRDGTHARQDSMEVKCQ 761
Query: 583 T-------------------------PVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFG 617
+V T Y APE+L Y++ D WSVG I
Sbjct: 760 LDEQCQCEILKPLERRRKREQRCLAHSLVGTPNYIAPEVLSRLGGYTSVCDWWSVGVILF 581
Query: 618 ELLTQKPLFPGNSEIDQINKVF 639
E+L P F N+ + KV
Sbjct: 580 EMLVGHPPFYANTPAETQYKVI 515
>13066
Length = 551
Score = 61.2 bits (147), Expect = 2e-09, Method: Composition-based stats.
Identities = 52/185 (28%), Positives = 87/185 (47%), Gaps = 6/185 (3%)
Frame = +3
Query: 435 GTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREIVVG 494
GT+ Y K +I+ ++ ++ ++ FP RE++ + K HP I+ + I+
Sbjct: 24 GTFNDGYGRNIKLACKIIDKEKAPVDFVEKFFP----RELDLLTKLDHPYIIQIHSIL-- 185
Query: 495 SNMDKIYIVMNYVEH-DLKSLMETMKQPFLP-GEVKTLMIQLLRGVKHLHDNWILHRDLK 552
K +I M + E DL + ++ + F+ + K Q+ + +LH + HRDLK
Sbjct: 186 QRXPKNFIFMRFAERGDLLTYIQEVG--FVKEKQAKIWFYQMTTALNYLHSYDVAHRDLK 359
Query: 553 TSNLLLSHAGILKVGDFGLA----REYGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVD 608
N+LLS +K+ DFG A E G + T + Y APE++ GA D
Sbjct: 360 CENILLSSHFNVKLADFGFACACITESGEKYMSRT-YCGSAAYAAPEIVYGAPYAPKVAD 536
Query: 609 MWSVG 613
WS+G
Sbjct: 537 AWSLG 551
>28638
Length = 1458
Score = 60.8 bits (146), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 33/81 (40%), Positives = 51/81 (62%), Gaps = 2/81 (2%)
Frame = -1
Query: 546 ILHRDLKTSNLLLSHA--GILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEY 603
I+H DLK N+LL + +K+ DFG + + G + Y + +++YR+PE+LLG Y
Sbjct: 768 IIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQY---IQSRFYRSPEVLLGVP-Y 601
Query: 604 STAVDMWSVGCIFGELLTQKP 624
A+DMWS+GCI E+ T +P
Sbjct: 600 DLAIDMWSLGCILVEMHTGEP 538
Score = 30.0 bits (66), Expect = 4.2, Method: Compositional matrix adjust.
Identities = 15/52 (28%), Positives = 22/52 (42%), Gaps = 5/52 (9%)
Frame = -2
Query: 603 YSTAVDMWSVGC-----IFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKI 649
Y W + C + PLF G++E DQ+ K+ + LG P I
Sbjct: 617 YXXCPMTWPLTCGXWAVYWWRCTXGNPLFAGSNEFDQMMKIVEVLGVPPRHI 462
>26909
Length = 394
Score = 60.1 bits (144), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 38/119 (31%), Positives = 57/119 (47%), Gaps = 16/119 (13%)
Frame = +2
Query: 615 IFGELLTQKPLFPGNSEI---------DQINKVFKELGTPSEKIWPGYSELPVVKKMT-- 663
IF ELLT +P+F E DQ++++F +G P EK W +P +++T
Sbjct: 2 IFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFPQEKDWEDIRRMPEHQQLTKD 181
Query: 664 FSEHPYNNLR-----KRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLP 717
F Y N ++ + F L+ K LT P +RI++E +K YF E PLP
Sbjct: 182 FKRSSYVNCNLMKYMEKHKVKADSKAFHLLQKLLTMDPVKRITSEQAMKDPYFLEEPLP 358
>19094
Length = 898
Score = 58.9 bits (141), Expect = 7e-09, Method: Compositional matrix adjust.
Identities = 31/105 (29%), Positives = 58/105 (55%), Gaps = 2/105 (1%)
Frame = +1
Query: 511 LKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFG 570
+ +M + + E+ T++ L+G+ +LH +HRD+K N+LL++ G K+ DFG
Sbjct: 16 VSDIMRLRNKTLVEREIATILYYTLKGL*YLHSRRKIHRDIKAGNILLNNEGHAKLADFG 195
Query: 571 LAREYGSPLKAYTPVVVTQWYRAPELL--LGAKEYSTAVDMWSVG 613
+A + + V+ T ++ APE++ +G Y D+WS+G
Sbjct: 196 VAGQLTDTMAKRNTVIGTPYWMAPEVIQEIG---YDCVADIWSLG 321
>21808
Length = 1011
Score = 58.2 bits (139), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 56/201 (27%), Positives = 96/201 (47%), Gaps = 14/201 (6%)
Frame = +1
Query: 452 VALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDL 511
VA+K LK P L E + K +HP ++ + V + D I+I+ +++
Sbjct: 28 VAIKTLKSGTMD---PKDFLAEAQIMKKLRHPKLIQL--YAVCTQDDPIFIITELMKNG- 189
Query: 512 KSLMETMKQPFLPGEVKTLMI--------QLLRGVKHLHDNWILHRDLKTSNLLLSHAGI 563
SL+E FL G+ + L + Q+ G+ +L +HRDL N+L+S
Sbjct: 190 -SLLE-----FLQGKGRVLKLPALIDIGAQIACGMAYLESQNYIHRDLAARNILVSDNNT 351
Query: 564 LKVGDFGLAR-----EYGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGE 618
+K+ DFGLAR EY + + A P+ +W APE ++ D+WS G + E
Sbjct: 352 VKIADFGLARVIKEDEYEARVGARFPI---KW-TAPE-AANYNRFTIKSDVWSFGILLTE 516
Query: 619 LLTQKPL-FPGNSEIDQINKV 638
+T + +PG + + +++V
Sbjct: 517 TVTYGRVPYPGMTNAEVLHQV 579
>24241
Length = 413
Score = 57.4 bits (137), Expect = 2e-08, Method: Composition-based stats.
Identities = 25/92 (27%), Positives = 57/92 (61%)
Frame = -2
Query: 429 LNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTV 488
L++I EGTYGVVY+ + + T +A+K++++ ++G P +++REI + + +H +
Sbjct: 328 LSKIGEGTYGVVYKCRHRATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTQXLVC 149
Query: 489 REIVVGSNMDKIYIVMNYVEHDLKSLMETMKQ 520
E V+ + +++++V ++ DLK ++ +
Sbjct: 148 LEDVIMED-ERLFLVFEFLSMDLKMYIDKFPE 56
>11185
Length = 473
Score = 56.6 bits (135), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 35/117 (29%), Positives = 56/117 (47%), Gaps = 22/117 (18%)
Frame = +1
Query: 527 VKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAY---- 582
++ I L+ G+ ++H IL DL+ S +LL +G+LK DFGL++ G L+
Sbjct: 7 IRDFGIHLVTGLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKF 186
Query: 583 ------------------TPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLT 621
P + Y APE+ GA E S D+W++GC+F E+ +
Sbjct: 187 AEAGDQWNIQSAEEMMKQVPTSGSPTYMAPEVFQGA-EPSIMSDLWALGCVFYEMFS 354
>19301
Length = 712
Score = 55.8 bits (133), Expect = 7e-08, Method: Compositional matrix adjust.
Identities = 43/149 (28%), Positives = 75/149 (50%), Gaps = 2/149 (1%)
Frame = +2
Query: 424 EEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHP 483
E L + G G V+ K E VA+K+++ KE + I +LR++N HP
Sbjct: 305 ESITDLEWLGSGAQGAVFLGK--LCAEEVAVKKVRDIKETD---IRNLRKLN------HP 451
Query: 484 NIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMK--QPFLPGEVKTLMIQLLRGVKHL 541
NI++ + + + I+M Y + L E ++ + P V Q+ G+ +L
Sbjct: 452 NIISFKGVC--TQAPCYCIIMEYCPYG--QLYEVLRDGKEIPPALVLDWSKQIASGMNYL 619
Query: 542 HDNWILHRDLKTSNLLLSHAGILKVGDFG 570
H + I+HRDLK+ N+L++ ++K+ DFG
Sbjct: 620 HSHKIIHRDLKSPNVLVAKNDVVKISDFG 706
>27405
Length = 532
Score = 55.8 bits (133), Expect = 7e-08, Method: Compositional matrix adjust.
Identities = 28/87 (32%), Positives = 51/87 (58%)
Frame = -3
Query: 522 FLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKA 581
F EV+ +++ G++H+H ++++RDLK +N+LL G +++ D GLA ++ K
Sbjct: 263 FTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGLACDFSK--KK 90
Query: 582 YTPVVVTQWYRAPELLLGAKEYSTAVD 608
V T Y APE+L+ + Y ++ D
Sbjct: 89 PHASVGTHGYMAPEVLMKGQAYDSSAD 9
>18287
Length = 678
Score = 55.5 bits (132), Expect = 7e-08, Method: Composition-based stats.
Identities = 35/119 (29%), Positives = 53/119 (44%), Gaps = 8/119 (6%)
Frame = -3
Query: 603 YSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKM 662
Y ++D+WSVGCIF ELL+++ LF + Q++ + +GTP + E
Sbjct: 673 YDYSIDIWSVGCIFAELLSRRILFQAQGPVQQLDMIINLVGTPRPEDMERACE------- 515
Query: 663 TFSEHPYNNLRKRFGALL--------SDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 713
H N +R L + + L+ + L P RISAE+ L H Y E
Sbjct: 514 GARNHILNQPFRRQNLLTLYNLSPHATHEAVRLLTRMLILNPKNRISAEEALSHPYLDE 338
>28157
Length = 400
Score = 55.5 bits (132), Expect = 8e-08, Method: Composition-based stats.
Identities = 44/129 (34%), Positives = 67/129 (51%), Gaps = 8/129 (6%)
Frame = +3
Query: 452 VALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSNMDK-IYIVMNYVEHD 510
VA+KR++ E+EK+ F ++E+ + + HPNIV + G+ D + +VM Y E
Sbjct: 9 VAVKRIESEQEKKSF----MQELKQLSRVSHPNIVCL----YGACRDHPVCLVMEYAEGG 164
Query: 511 --LKSLMETMKQP-FLPGEVKTLMIQLLRGVKHLHD---NWILHRDLKTSNLLLSHAGI- 563
L + QP + ++Q GV++LH ++HRDLK NLLL G
Sbjct: 165 SLYNVLHGSGPQPQYTAAHAMNWLLQCALGVEYLHGMKPKALIHRDLKPPNLLLIQCGTK 344
Query: 564 LKVGDFGLA 572
LK+ DFG A
Sbjct: 345 LKICDFGTA 371
>31489
Length = 329
Score = 55.5 bits (132), Expect = 9e-08, Method: Composition-based stats.
Identities = 28/81 (34%), Positives = 50/81 (61%), Gaps = 4/81 (4%)
Frame = +3
Query: 481 QHPNIVTVREIVVGSN----MDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLR 536
+H NI+++REI+ + I++V + +E DL ++ + QP ++ + Q+LR
Sbjct: 24 KHDNIISIREILKPKDSYHDFKDIHVVFDLMESDLHRIIYS-DQPLTEEHIRYFLYQILR 200
Query: 537 GVKHLHDNWILHRDLKTSNLL 557
G+K++H ++HRDLK SNLL
Sbjct: 201 GLKYIHSANVVHRDLKPSNLL 263
>07940
Length = 1336
Score = 55.1 bits (131), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 35/112 (31%), Positives = 56/112 (50%), Gaps = 6/112 (5%)
Frame = -3
Query: 516 ETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLARE- 574
+ M + P ++ + Q+ RG+++L +HRDL N+L++ +LK+ DFGL R
Sbjct: 374 QDMLKMLTPKDLISYAYQVARGMEYLASKQCIHRDLAARNVLVAEEYVLKIADFGLTRNL 195
Query: 575 -----YGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLT 621
Y PV +W APE L K Y++ D+WS G + E+ T
Sbjct: 194 QQFDYYRKTTDGRLPV---KW-MAPEALFDRK-YTSKSDVWSYGVLLWEIFT 54
>26711
Length = 405
Score = 55.1 bits (131), Expect = 1e-07, Method: Composition-based stats.
Identities = 39/111 (35%), Positives = 61/111 (54%), Gaps = 6/111 (5%)
Frame = -2
Query: 533 QLLRGVKHLHDNWILHRDLKTSNLLLSHAGI--LKVGDFGLAREYGSPLKAY----TPVV 586
Q+L ++H+H ++H DLK SNLLLS + +++ DFGLAR+ P + + TP
Sbjct: 392 QVLDILQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARKLYPPQETFLNHGTP-- 219
Query: 587 VTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINK 637
+ +PE L K STA D+W VG + LL+ + F +S + + K
Sbjct: 218 ---GFTSPE-ALDVKPISTASDVWGVGVLAYILLSGQSPFQADSATESLKK 78
>17253
Length = 483
Score = 53.5 bits (127), Expect = 3e-07, Method: Composition-based stats.
Identities = 44/140 (31%), Positives = 67/140 (47%), Gaps = 14/140 (10%)
Frame = -1
Query: 460 EKEKEGFPITSLREINTILK-AQHPNIVTVREIVVGSNMDKIYIVMNYVEH-DLKSLMET 517
+ EK F LRE++ + K +HPN+V+ S D I+M + H DL S +
Sbjct: 426 DAEKSEF----LRELSIMRKLPRHPNVVSFMGCCTMS--DPALILMEFCCHGDLLSFLRK 265
Query: 518 MKQP----FLPGEVKTLM--------IQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILK 565
++P FL L + + RG+ H+ +N I+HRD+ N+L+S + K
Sbjct: 264 -RRPDRTVFLTSTANDLTARDFFSFALHVARGMAHVANNKIVHRDVAARNVLISERNVCK 88
Query: 566 VGDFGLAREYGSPLKAYTPV 585
V DFGL+R G Y V
Sbjct: 87 VSDFGLSRRVGDQNDVYEIV 28
>04852
Length = 1462
Score = 52.8 bits (125), Expect = 6e-07, Method: Compositional matrix adjust.
Identities = 30/90 (33%), Positives = 48/90 (53%)
Frame = +1
Query: 532 IQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWY 591
Q+ RG++ L +HRDL N+L++ +LK+ DFGL+R K + +W
Sbjct: 346 FQIARGMEFLASRKCIHRDLAARNVLVTEEHVLKIADFGLSRTGDYYKKRSGGRLPVKWM 525
Query: 592 RAPELLLGAKEYSTAVDMWSVGCIFGELLT 621
APE L + Y+T D+WS G + E+ +
Sbjct: 526 -APEALFDMR-YTTKSDVWSFGVVLWEIFS 609
>00715
Length = 1788
Score = 52.0 bits (123), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 48/177 (27%), Positives = 84/177 (47%), Gaps = 29/177 (16%)
Frame = +1
Query: 481 QHPNIVTVREIVVGSNM-----DKIYIVMNYV-EHDLKSLMETMKQPFLPGEVKTLMIQL 534
+H N+V++ +G+ D ++ M YV +L++++ +Q +L +Q+
Sbjct: 100 RHVNVVSI----LGATSLHRFEDGAWLAMEYVGPLNLQTILNDHQQDIDSSMRLSLALQM 267
Query: 535 LRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREY---------------GSPL 579
RG+ +LH I+H DLK +N LL+ L++ DFG + G+ L
Sbjct: 268 ARGLHYLHSINIVHLDLKPANCLLTRDLKLRIADFGCCHQLTPTGLDMGEREGGMAGNEL 447
Query: 580 KAYTPV--------VVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPG 628
+ TPV T YRAPELL G + S D++S+G ++ T++ + G
Sbjct: 448 E-LTPVQGAWKNELAGTLAYRAPELLKGLQP-SVRSDVYSLGITLWQMCTRQGPYEG 612
>18401
Length = 463
Score = 52.0 bits (123), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 39/144 (27%), Positives = 66/144 (45%), Gaps = 14/144 (9%)
Frame = -3
Query: 582 YTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKE 641
++ +V T+ YRAPE++L +S D+WSVGCI EL T LF + + + + +
Sbjct: 461 HSTIVSTRHYRAPEVILELG-WSHPCDVWSVGCIMFELYTGYTLFQTHDNKEHLAMMERI 285
Query: 642 LGTPSEKI--------WPGYSELPVVKKMTFSEHPYNNLRKRFGALLS------DQGFDL 687
LG+ ++ + + L V ++ + + + N + + Q FDL
Sbjct: 284 LGSLPYRMAKKTKKQKYFHHGRLDVPERSSMARYVRENTKPLLRYVKDRENKDHQQLFDL 105
Query: 688 MNKFLTYFPGRRISAEDGLKHEYF 711
M K L Y R S L+H +F
Sbjct: 104 MKKLLAYEASSRYSLLQALQHPFF 33
>21079
Length = 878
Score = 50.8 bits (120), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 34/91 (37%), Positives = 50/91 (54%), Gaps = 2/91 (2%)
Frame = +1
Query: 533 QLLRGVKHLHDNWILHRDLKTSNLLL--SHAGILKVGDFGLAREYGSPLKAYTPVVVTQW 590
Q+ GV ++H ILH DLK N+L ++ +K+ DFGLAR Y P + + T
Sbjct: 151 QICSGVGYMHTQSILHLDLKPENVLCVSDNSNQIKIIDFGLARFY-KPGDSLQVLFGTPE 327
Query: 591 YRAPELLLGAKEYSTAVDMWSVGCIFGELLT 621
+ APE ++ E + DMWS+G I LL+
Sbjct: 328 FIAPE-VVNYDEINFTTDMWSIGVICYILLS 417
>12672
Length = 773
Score = 50.8 bits (120), Expect = 2e-06, Method: Composition-based stats.
Identities = 31/89 (34%), Positives = 50/89 (56%), Gaps = 4/89 (4%)
Frame = +3
Query: 537 GVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREY----GSPLKAYTPVVVTQWYR 592
G+++L+DN +HRD+KT+N+LL KVGDF G ++ + V+ T Y
Sbjct: 27 GIQYLNDNGHVHRDIKTANILLDSEYTAKVGDFATVVSAPSGEGKTVQNASVVIGTAAYL 206
Query: 593 APELLLGAKEYSTAVDMWSVGCIFGELLT 621
APE + + ST +D +S G + E++T
Sbjct: 207 APEAI--HFDVSTKLDSYSFGVVLLEVIT 287
>16003
Length = 926
Score = 50.4 bits (119), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 35/99 (35%), Positives = 51/99 (51%)
Frame = -1
Query: 619 LLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKMTFSEHPYNNLRKRFGA 678
LL + P PG++++DQ+ K+F LGTP+E WP + LP + F L++ F A
Sbjct: 926 LLIRLPFLPGDTDLDQLGKIFNMLGTPTETEWPAVTSLP--DYIQFKHCQKQPLKEIFTA 753
Query: 679 LLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLP 717
D +L++K L P R +A LK YF P P
Sbjct: 752 -AGDDLLELLDKLLAMNPLHRCTATQALKMPYFSNKPYP 639
>00392
Length = 668
Score = 50.4 bits (119), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 46/163 (28%), Positives = 74/163 (45%), Gaps = 6/163 (3%)
Frame = +3
Query: 481 QHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTL---MIQLLRG 537
QHPNIV + N +++ E ++T + F VK L Q+L+G
Sbjct: 105 QHPNIVRFFDYWEEHNHRNRKVIILVTELMTSGTLKTYLKRFKKPNVKILKNWCRQVLKG 284
Query: 538 VKHLHDNW--ILHRDLKTSNLLLSH-AGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAP 594
+ LH ++HRDLK N+ ++ G +K+GD GLA V+ T + AP
Sbjct: 285 LYFLHTRTPPVIHRDLKCDNIFITGPTGSVKIGDLGLATLKNQSFAK--SVIGTPEFMAP 458
Query: 595 ELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINK 637
E+ + Y AVD+++ G E+ + + + S QI K
Sbjct: 459 EMY--EEHYDEAVDVYAFGMCMLEMASSEYPYSECSNAAQIYK 581
>12786
Length = 460
Score = 50.1 bits (118), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 38/117 (32%), Positives = 58/117 (49%), Gaps = 23/117 (19%)
Frame = -3
Query: 533 QLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLA----REYGSPLKAYTPVVVT 588
++LR VK LH+ ++H DLK +N +L AG LK+ DFG+A ++ S LK V T
Sbjct: 386 EMLRAVKALHNEGVIHSDLKPANFMLV-AGNLKLIDFGIANTLQQDKTSVLK--DSRVGT 216
Query: 589 QWYRAPELLLGAKE-----------------YSTAV--DMWSVGCIFGELLTQKPLF 626
Y +PE ++ A + Y V D+WS+GCI ++ + F
Sbjct: 215 PSYMSPEAIMAACDDSADDSMEEDGHRTKPKYKVGVRSDVWSLGCILYNMVYGRTPF 45
>17300
Length = 480
Score = 49.3 bits (116), Expect = 6e-06, Method: Composition-based stats.
Identities = 31/90 (34%), Positives = 51/90 (56%), Gaps = 5/90 (5%)
Frame = +1
Query: 537 GVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLK--AYTP---VVVTQWY 591
G+ L D +HRDL N+L++ + KV DFGL+RE S AYT + +W
Sbjct: 10 GMGXLADMGYVHRDLAARNILVNEILVCKVADFGLSREIESDTTEGAYTTKGGKIPVRW- 186
Query: 592 RAPELLLGAKEYSTAVDMWSVGCIFGELLT 621
APE + +++++A D+WS G + E+++
Sbjct: 187 TAPE-AIAYRKFTSASDVWSFGVVMWEVMS 273
>31885
Length = 529
Score = 47.4 bits (111), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 46/161 (28%), Positives = 73/161 (45%), Gaps = 4/161 (2%)
Frame = -2
Query: 474 INTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQ 533
++ + + HP +V + D +V ++ DL+ M+ + F VK + Q
Sbjct: 519 VDMLTRLDHPFLVNLW-YAFQDEEDLFMVVDLFLGGDLRYHMQQ-EVSFREDCVKFYLCQ 346
Query: 534 LLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRA 593
L + +L I+HRD+K N+LL G V DF +A + A T T+ Y A
Sbjct: 345 LALVLDYLRSQKIVHRDIKPDNILLDEQGHCHVTDFNIATQLEDDELA-TSTSGTRPYMA 169
Query: 594 PELLLGA----KEYSTAVDMWSVGCIFGELLTQKPLFPGNS 630
PE+ A + Y VD WS+G ELL ++ F +S
Sbjct: 168 PEVYGVAINERRGYGFPVDWWSLGVSLFELLKKRRPFSVHS 46
>11780
Length = 1713
Score = 45.8 bits (107), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 51/202 (25%), Positives = 98/202 (48%), Gaps = 4/202 (1%)
Frame = +3
Query: 432 IEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREI 491
I +G +G VY+ + + VA+K+LK +K+ + L+E + + +H N+V + +
Sbjct: 621 IGKGDFGDVYKGMYR--GQPVAIKQLK---DKDRGEQSFLQEASVMTSLRHDNLVRLIGV 785
Query: 492 VVGSNMDKIYIVMNYV-EHDLKSLMETMKQPFLPGEVK-TLMIQLLRGVKHLHDNWILHR 549
V+G + I++V ++ + +L + + + + + + +++L ++HR
Sbjct: 786 VLG---ETIFLVTEFMGKGNLVEYLRSRGRSVITKKDQINFATDTCAAMEYLESKRLVHR 956
Query: 550 DLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEY--STAV 607
DL N+L+ G KV DFGLA+ +G + T V + APE L K + V
Sbjct: 957 DLAARNVLVHDDGKAKVSDFGLAK-FGDF--SQTSVKFPIKWTAPEALRENKIH*QVRHV 1127
Query: 608 DMWSVGCIFGELLTQKPLFPGN 629
++W + + G LL P N
Sbjct: 1128ELWHI--VMGNLLLWSSALP*N 1187
>05084
Length = 1324
Score = 44.7 bits (104), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 28/92 (30%), Positives = 43/92 (46%), Gaps = 4/92 (4%)
Frame = +2
Query: 626 FPGNSEIDQINKVFKELGTPS----EKIWPGYSELPVVKKMTFSEHPYNNLRKRFGALLS 681
PG+S +DQ+ ++ K LGTP+ ++ P YSE K HP+ K F
Sbjct: 2 LPGDSGVDQLVEIIKVLGTPTREQIREMNPNYSEF---KFPQIKAHPWT---KVFRPRTP 163
Query: 682 DQGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 713
+ L+++ L Y P RI + H +F E
Sbjct: 164 PEAIQLVSRLLEYTPSARIQPMEACAHAFFDE 259
>20640
Length = 1492
Score = 44.3 bits (103), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 26/79 (32%), Positives = 40/79 (50%), Gaps = 4/79 (5%)
Frame = +1
Query: 547 LHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYT----PVVVTQWYRAPELLLGAKE 602
+HRDL T N L+ H ++K+ DFGLAR S + Y + +W +L +
Sbjct: 10 VHRDLATRNCLVGHDLVVKISDFGLARSVHS-VDYYRGSEHDAIPIRWMPLEAILYN--K 180
Query: 603 YSTAVDMWSVGCIFGELLT 621
+ST D+WS G + E+
Sbjct: 181 FSTQSDVWSFGVVLWEIFA 237
>07836
Length = 1478
Score = 43.5 bits (101), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 53/190 (27%), Positives = 85/190 (44%), Gaps = 20/190 (10%)
Frame = -1
Query: 450 EIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIV--TVREIVVGSNMDKIYIVMNYV 507
E VA+K +E F T L + T+L +H NI+ +I + +++++ +Y
Sbjct: 1475 ENVAVKIFFTTEEASWFRETELYQ--TVL-LRHENILGFIAADIKGTGSWTQLFLITDY- 1308
Query: 508 EHDLKSLMETMKQPFL-PGEVKTLMIQLLRGVKHLHDNW--------ILHRDLKTSNLLL 558
H+ SL + + L E+ L + G+ HLH I HRD+K+ N+L+
Sbjct: 1307 -HENGSLHDYLLSRVLDSSEMLALAHSAICGLAHLHIEIFGTRGKPAIAHRDIKSKNILV 1131
Query: 559 SHAGILKVGDFGLAREYGSPLK----AYTPVVVTQWYRAP---ELLLGAKEYST--AVDM 609
G + D GLA Y S A P T+ Y AP E+LL K + DM
Sbjct: 1130 KKNGTCCIADLGLAVRYISESNEVDVAPNPRQGTKRYMAPEVLEMLLNVKNFDAFKQADM 951
Query: 610 WSVGCIFGEL 619
++ G + E+
Sbjct: 950 YAFGLVMWEI 921
>17975
Length = 449
Score = 43.1 bits (100), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 35/146 (23%), Positives = 67/146 (45%), Gaps = 10/146 (6%)
Frame = +3
Query: 437 YGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSN 496
+ VV A+ T E VA+K + K E +E+ + QHPN+V + E++
Sbjct: 6 FAVVKLARHVFTGEKVAVKVIDKTKLDEVSRSHLFQEVRCMKLVQHPNVVRLYEVI--DT 179
Query: 497 MDKIYIVM---------NYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWIL 547
K+Y+++ +Y+ L E + + + Q++ + + H ++
Sbjct: 180 QTKLYLILELGDGGDMYDYIMRHSGGLEEKLAKRYFR--------QIVEAISYCHKLHVV 335
Query: 548 HRDLKTSNLLLSHA-GILKVGDFGLA 572
HRDLK N++ G++K+ DFG +
Sbjct: 336 HRDLKPENVVFFEKPGLVKLTDFGFS 413
>21433
Length = 590
Score = 42.0 bits (97), Expect = 9e-04, Method: Compositional matrix adjust.
Identities = 33/94 (35%), Positives = 50/94 (53%)
Frame = +2
Query: 531 MIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQW 590
+ QL +++ H ++HRD+K NLLL G LK+ DFG + +P T + T
Sbjct: 185 IYQLSSALEYCHYRKVIHRDIKPENLLLGLKGDLKIADFGWSVH--APSSRRTTMCGTLD 358
Query: 591 YRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKP 624
Y PE++ G K + VD+WS+G + E L P
Sbjct: 359 YLPPEMVEG-KTHDENVDLWSLGVLCYEFLVGTP 457
>07291
Length = 833
Score = 41.6 bits (96), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 28/96 (29%), Positives = 50/96 (52%), Gaps = 6/96 (6%)
Frame = +1
Query: 533 QLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGS--PLKAYT----PVV 586
Q+ G+ +L + ++HR+L N +++ G L++ D+G+ GS P YT P
Sbjct: 73 QIADGMAYLQEVKVVHRNLAARNCIVTEDGRLQLSDYGVT---GSLFPQSYYTADDSPAR 243
Query: 587 VTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQ 622
+ APE + +S+ D+W+ G + ELLT+
Sbjct: 244 DLVKWMAPE-TIDNFHFSSKSDVWAFGVVLWELLTR 348
>15549
Length = 470
Score = 39.7 bits (91), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 15/39 (38%), Positives = 29/39 (74%)
Frame = -1
Query: 421 RSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKM 459
R +EF+C+ ++ +G YG+V+RAK+K ++ A+KR+ +
Sbjct: 227 RFADEFECIEQMGKGGYGIVFRAKNKVDEQEYAVKRIAL 111
>18481
Length = 437
Score = 39.3 bits (90), Expect = 0.006, Method: Composition-based stats.
Identities = 28/99 (28%), Positives = 46/99 (46%), Gaps = 3/99 (3%)
Frame = -1
Query: 480 AQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVK 539
+HP + T+ G+ +VM + L+ L K+ F + + QLL ++
Sbjct: 326 GRHPGLPTMYH--YGTEKHFNALVMELLGPSLEELFVICKRRFTLKTILMVSDQLLSRLE 153
Query: 540 HLHDNWILHRDLKTSNLLLS---HAGILKVGDFGLAREY 575
+H +HRDLK N L+ H L + DFGL++ Y
Sbjct: 152 FIHQKCFIHRDLKPDNFLMGLGRHCHRLYIIDFGLSKRY 36
>16708
Length = 1397
Score = 38.9 bits (89), Expect = 0.007, Method: Compositional matrix adjust.
Identities = 16/52 (30%), Positives = 31/52 (59%)
Frame = -1
Query: 524 PGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREY 575
P V + Q + ++H+H+ ++H D+K N+L+ G K+ D+G+A+ Y
Sbjct: 1097 PAMVCCIAGQXVCALEHIHELGVVHMDVKADNVLVDAHGNCKLTDYGIAQLY 942
>14477
Length = 493
Score = 38.9 bits (89), Expect = 0.007, Method: Compositional matrix adjust.
Identities = 41/147 (27%), Positives = 70/147 (47%), Gaps = 4/147 (2%)
Frame = -1
Query: 431 RIEEGTYGVVYRAKDKKTD-EI-VALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTV 488
++ G +G V + + D EI VA+K LK ++E + K H +IV +
Sbjct: 469 KLGAGNFGSVMKGVCRLDDREIPVAIKVLKNADLDPSVQSELIKEAEVMKKMDHMHIVRL 290
Query: 489 REIVVGSNMDKIYIVMNYVEHDLKSLMETM-KQPFLP-GEVKTLMIQLLRGVKHLHDNWI 546
+ G M +V+ + L L + + K LP + LM Q+ +G+++L N
Sbjct: 289 IGLCEGETM---MLVLELAK--LGPLNKFLPKNKHLPLWNILELMWQVSQGMEYLEANKF 125
Query: 547 LHRDLKTSNLLLSHAGILKVGDFGLAR 573
+HRDL N+LL K+ DFG+++
Sbjct: 124 VHRDLAARNILLCDEHFAKISDFGMSK 44
>26009
Length = 886
Score = 32.0 bits (71), Expect(2) = 0.007, Method: Compositional matrix adjust.
Identities = 12/33 (36%), Positives = 22/33 (66%)
Frame = +3
Query: 526 EVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLL 558
E K++M QL+ + +H ++HRD+K N+L+
Sbjct: 714 EAKSVMKQLVSALDFMHSKQLVHRDIKPENVLI 812
Score = 25.8 bits (55), Expect(2) = 0.007, Method: Compositional matrix adjust.
Identities = 23/93 (24%), Positives = 35/93 (37%), Gaps = 5/93 (5%)
Frame = +2
Query: 424 EEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREIN-----TIL 478
E + + GTYG V A+ + T VALK L T LRE +
Sbjct: 416 EHYDVCKELGRGTYGKVVLARCRHTGTQVALKLLPKS-------CTKLREFQREFQLSYF 574
Query: 479 KAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDL 511
+ H NI+ + + ++ + V DL
Sbjct: 575 LSPHANIIDTYNVAFQTRSSYVFAQEHAVLGDL 673
>37602
Length = 804
Score = 38.9 bits (89), Expect = 0.009, Method: Compositional matrix adjust.
Identities = 20/72 (27%), Positives = 39/72 (54%)
Frame = -1
Query: 498 DKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLL 557
+K++I M Y + + P ++ + + L+G+ +LH +HRD+K +N+L
Sbjct: 300 EKLWIAMEYCGGGSMQDIYHVTGPLTEPQIAFVCRETLKGLHYLHRRGKMHRDIKGANIL 121
Query: 558 LSHAGILKVGDF 569
L+ G +K+ DF
Sbjct: 120 LTEEGDVKLADF 85
>13078
Length = 773
Score = 38.1 bits (87), Expect = 0.014, Method: Compositional matrix adjust.
Identities = 31/125 (24%), Positives = 59/125 (47%), Gaps = 14/125 (11%)
Frame = -1
Query: 603 YSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKI--------WPGYS 654
+S D+WS+GCI EL T LF + + + + + LG+ ++ + +
Sbjct: 746 WSQPCDVWSIGCIMFELYTGYTLFQTHDNKEHLAMMERILGSLPYRMAKKTKKQKYFYHG 567
Query: 655 ELPVVKKMTFSEHPYNNLR--KRFGALLSD----QGFDLMNKFLTYFPGRRISAEDGLKH 708
L +K + + +N++ +R+ + Q FDLM+K L+Y R S ++H
Sbjct: 566 RLDWDEKSSAGRYVRDNVKPLRRYVKDPDNEDHQQLFDLMDKMLSYEVSTRYSLRQAMRH 387
Query: 709 EYFRE 713
+FR+
Sbjct: 386 PFFRK 372
>02638
Length = 1490
Score = 37.7 bits (86), Expect = 0.018, Method: Composition-based stats.
Identities = 18/50 (36%), Positives = 30/50 (60%)
Frame = +1
Query: 591 YRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFK 640
+ APE+L G + Y A D+WSVGC+ E+ T +P + + + + +FK
Sbjct: 34 FMAPEVLRG-ESYGRACDVWSVGCVMIEMCTCRPPWNSHDISNHLALIFK 180
>00486
Length = 797
Score = 35.4 bits (80), Expect = 0.099, Method: Compositional matrix adjust.
Identities = 18/50 (36%), Positives = 27/50 (54%)
Frame = -2
Query: 591 YRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFK 640
Y APE+L + AVD WS+G + ++LT P F + I+K+ K
Sbjct: 760 YMAPEILTRTG-HGKAVDWWSLGALMYDMLTGSPPFTAENRKKTIDKILK 614
>36481
Length = 806
Score = 33.5 bits (75), Expect = 0.33, Method: Compositional matrix adjust.
Identities = 37/149 (24%), Positives = 66/149 (44%), Gaps = 6/149 (4%)
Frame = +2
Query: 416 ALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLK-MEKEKEGFPITSLREI 474
++G S + + EGT+G V + KD + +ALK +K ++K +E + EI
Sbjct: 338 TMRGTSSTNDMKLCPHWGEGTFGKVVQCKDLLKGDDIALKIIKNVDKYREAAKL----EI 505
Query: 475 NTILKAQ----HPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGE-VKT 529
N + K + H + V+ + + I + + + ++ P E V+
Sbjct: 506 NVLEKLREKDPHAKHMCVQMLDWFDYHGHVCISFHMLGLSVFDFLKDNSYGAYPIEQVRH 685
Query: 530 LMIQLLRGVKHLHDNWILHRDLKTSNLLL 558
+ QL V LH+N + H DLK N+L
Sbjct: 686 ISYQLCYAVNFLHENQLTHTDLKPENILF 772
>15931
Length = 447
Score = 30.4 bits (67), Expect = 2.6, Method: Compositional matrix adjust.
Identities = 13/31 (41%), Positives = 19/31 (61%)
Frame = +1
Query: 683 QGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 713
Q FDLM+K L+Y R S ++H +FR+
Sbjct: 70 QLFDLMDKMLSYEVSTRYSLRQAMRHPFFRK 162
>00145
Length = 2325
Score = 30.0 bits (66), Expect = 3.4, Method: Composition-based stats.
Identities = 18/46 (39%), Positives = 24/46 (52%), Gaps = 1/46 (2%)
Frame = -1
Query: 696 PGRRISAEDGLKHEYFRETP-LPIDPSMFPTWPAKSEQQRVKRGTS 740
P RIS DG + RE+P LP D + P P + Q+ V R T+
Sbjct: 2313 PQHRISQSDGESVDVQRESPLLPRDGAAVPQRPGPAAQEGVSRQTA 2176
>20152
Length = 445
Score = 30.0 bits (66), Expect = 4.1, Method: Compositional matrix adjust.
Identities = 14/33 (42%), Positives = 20/33 (60%)
Frame = +1
Query: 594 PELLLGAKEYSTAVDMWSVGCIFGELLTQKPLF 626
PE+LLG + AVD+WS+G I L+ + F
Sbjct: 1 PEILLGDSYDAPAVDVWSLGVILYMLVVGEAPF 99
>38560
Length = 479
Score = 29.3 bits (64), Expect = 6.6, Method: Composition-based stats.
Identities = 12/30 (40%), Positives = 18/30 (60%)
Frame = -3
Query: 591 YRAPELLLGAKEYSTAVDMWSVGCIFGELL 620
Y APEL+ G + + D+WS+G + LL
Sbjct: 387 YAAPELISGLEYLGSEADIWSMGVLLYALL 298
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000383875 | hsapiens_gene_ensembl | PITSLRE
serine/threonine-protein kinase CDC2L2 (EC 2.7.11.22)
(Galactosyltransferase-associated protein kinase p58/GTA) (Cell
division cycle 2-like protein kinase 2) (CDK11).
[Source:Uniprot/SWISSPROT;Acc:Q9UQ88]
(780 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
29581 292 4e-84
01060 229 4e-60
01756 222 4e-58
14126 219 3e-57
04591 195 5e-50
32000 170 2e-42
01707 162 4e-40
04138 151 1e-36
01966 118 3e-28
23319 103 3e-22
00300 95 1e-19
03294 87 2e-17
18921 86 7e-17
06405 83 3e-16
13592 82 6e-16
12721 82 1e-15
01718 80 5e-15
09606 77 2e-14
03508 77 4e-14
20559 66 1e-13
12453 74 2e-13
14420 73 4e-13
15910 71 2e-12
26560 68 1e-11
19761 65 8e-11
18484 65 9e-11
21578 64 2e-10
27546 63 5e-10
03240 62 1e-09
14116 62 1e-09
30755 61 1e-09
13066 61 2e-09
13212 61 2e-09
28638 61 2e-09
26909 60 3e-09
19094 59 8e-09
21808 58 1e-08
11185 57 4e-08
19301 56 7e-08
27405 56 7e-08
18287 56 7e-08
07940 55 8e-08
24241 55 9e-08
26711 55 1e-07
28157 55 1e-07
31489 55 2e-07
17253 53 4e-07
04852 53 6e-07
18401 52 1e-06
00715 52 1e-06
21079 51 2e-06
12672 51 2e-06
16003 50 2e-06
00392 50 3e-06
12786 50 4e-06
17300 49 5e-06
31885 47 2e-05
11780 46 7e-05
05084 45 1e-04
20640 44 2e-04
07836 44 3e-04
17975 44 4e-04
21433 42 0.001
07291 42 0.001
15549 40 0.003
02638 39 0.006
14477 39 0.008
26009 32 0.008
37602 39 0.008
16708 39 0.009
18481 38 0.014
13078 38 0.015
00486 35 0.090
36481 33 0.42
15931 30 2.6
00145 30 3.0
20152 30 3.9
38560 29 6.5
>29581
Length = 1278
Score = 292 bits (747), Expect(2) = 4e-84, Method: Compositional matrix adjust.
Identities = 133/261 (50%), Positives = 183/261 (70%)
Frame = -2
Query: 474 ILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLR 533
+L +H NIV ++E+VVG ++D +++VM Y E DL SL++ M PF +VK +++QLL+
Sbjct: 1193 LLNLRHQNIVQLQEVVVGKSLDSLFLVMEYCEQDLASLLDNMPAPFSESQVKCIVLQLLK 1014
Query: 534 GVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPEL 593
G+++LH+ +I+HRDLK SNLL++ G +K+ DFGLAR YG P K TP VVT WYRAPEL
Sbjct: 1013 GLRYLHEAFIIHRDLKVSNLLMTDKGCVKIADFGLARNYGKPQKPMTPKVVTLWYRAPEL 834
Query: 594 LLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSEL 653
L G+K +STA+DMWS GCI GELL KPL PG S++ QI + + LGTP++ IWPG+S+L
Sbjct: 833 LFGSKTHSTAIDMWSAGCILGELLGHKPLMPGRSDLQQIELIMELLGTPNDTIWPGFSQL 654
Query: 654 PVVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPL 713
P ++ T + PYNNLR F LS+ G L+N Y P +R +AED L+H YF+E P
Sbjct: 653 PAFEQFTLKKQPYNNLRHTF-PWLSESGIRLLNGLFMYHPQKRATAEDCLEHSYFKEQPY 477
Query: 714 PIDPSMFPTWPAKSEQQRVKR 734
P DP P++P Q R+KR
Sbjct: 476 PCDPEFMPSFP----QHRLKR 426
Score = 38.9 bits (89), Expect(2) = 4e-84, Method: Composition-based stats.
Identities = 17/35 (48%), Positives = 25/35 (71%)
Frame = -1
Query: 446 DEIVALKRLKMEKEKEGFPITSLREINTILKAQHP 480
+EIVALK+++M E+ G PI+ LREIN ++ P
Sbjct: 1278 NEIVALKKMRMTGERYGIPISGLREINIFAQSATP 1174
>01060
Length = 1800
Score = 229 bits (583), Expect = 4e-60, Method: Compositional matrix adjust.
Identities = 122/338 (36%), Positives = 204/338 (60%), Gaps = 2/338 (0%)
Frame = +1
Query: 398 LLPIELKQELPKYLPALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKME 457
LL + +K+ + + AL + +FQ +I EGTYGVVY+ + + T +A+K++++
Sbjct: 22 LLKLNIKRLMMDFETALS---DLTDFQ---KIGEGTYGVVYKCRHRATGRKLAMKKIRLR 183
Query: 458 KEKEGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQ 517
++G P +++REI + + +H NIV + ++++ +++++V ++ DLK ++ +
Sbjct: 184 GSEDGVPSSAIREIAMLRELRHTNIVCLEDVIMED--ERLFLVFEFLSMDLKMYIDKFPE 357
Query: 518 PFLPGE--VKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSP 575
+ VK+ + Q++ G+ H I+HRDLK NLL++H G +K+ DFG+AR + P
Sbjct: 358 GVVLDRRLVKSYVFQIVTGIXFCHQRRIVHRDLKPQNLLINHTGAIKIADFGMARTFALP 537
Query: 576 LKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKV 635
++AYT VVT WYRAPE+L+GA +YST VD+WS+G IF ++L + P+F G+SEIDQ+ K+
Sbjct: 538 VRAYTHEVVTLWYRAPEILMGASKYSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKI 717
Query: 636 FKELGTPSEKIWPGYSELPVVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGR 695
F+ +GTP+E+ WP + +LP M F L + L S G DL+ + L P +
Sbjct: 718 FRIIGTPTEQTWPEFHKLPAFNGM-FPLWKEGKLSETLTDLDS-LGLDLIERTLKCDPAQ 891
Query: 696 RISAEDGLKHEYFRETPLPIDPSMFPTWPAKSEQQRVK 733
RIS + L+H YF + P P+ P S R+K
Sbjct: 892 RISCKKMLQHAYFLNVDTSVKPVDVPS-PEHS*STRLK 1002
>01756
Length = 1858
Score = 222 bits (566), Expect = 4e-58, Method: Compositional matrix adjust.
Identities = 117/309 (37%), Positives = 187/309 (60%), Gaps = 10/309 (3%)
Frame = -3
Query: 417 CRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILK 476
C +++ L +I +GT+G V++A+ KKT ++VA+K++ M+ EKEGFPIT+LREI +
Sbjct: 1754 CDEDAKYEKLAKIGQGTFGEVFKARCKKTKQVVAMKKVLMDNEKEGFPITALREIKILQL 1575
Query: 477 AQHPNIVTVREIV----VGSNMDK--IYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQ 530
H N+V + EI +N K Y+V + EHDL L+ M F E+K +M Q
Sbjct: 1574 LNHENVVDLIEICSTKATSANRYKSMFYLVFEFCEHDLAGLLSNMSVVFNLPEIKEVMKQ 1395
Query: 531 LLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKA---YTPVVVTQW 587
L+ G+ ++H N ILHRD+K +N+L++ G+LK+ DFGLAR + L+ YT VVT W
Sbjct: 1394 LMNGLYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLW 1215
Query: 588 YRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIW 647
YR PELLLG + YSTA+D W GCI E+ T+ P+ G +E +Q+ + + G+ + ++W
Sbjct: 1214 YRPPELLLGDRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQNQLTLITQLCGSITPEVW 1035
Query: 648 PGYSELPVVKKMTFSEHPYNNLRKRFGALLSDQ-GFDLMNKFLTYFPGRRISAEDGLKHE 706
PG L + + + +++R + D DL++K L PG+R+++++ L H+
Sbjct: 1034 PGVERLELYNSLDLPQGNKRKVKERLRYYIKDAYALDLLDKLLALDPGKRVNSDEALSHD 855
Query: 707 YFRETPLPI 715
+F P P+
Sbjct: 854 FFWMDPEPL 828
>14126
Length = 1265
Score = 219 bits (559), Expect = 3e-57, Method: Compositional matrix adjust.
Identities = 125/299 (41%), Positives = 182/299 (60%), Gaps = 9/299 (3%)
Frame = +3
Query: 421 EEFQCLNRIEEGTYGVVYRAKD-KKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQ- 478
++++ + I G YG VY+A+D + E VA+KR+++ +EG P+ ++REI+ + + +
Sbjct: 189 QKYEEVAVIGNGAYGTVYKARDLRNQGEFVAMKRIRLNNTEEGMPMMAIREISMLKQLEQ 368
Query: 479 --HPNIVTVREIVVGSNMDK---IYIVMNYVEHDLKSLMETMKQPFL-PGEVKTLMIQLL 532
HPN+V + ++ + D+ + +V Y+EHDL + + P L P +K LM+QLL
Sbjct: 369 YEHPNVVRLLDVSHNTITDREIRLNLVFEYIEHDLATYLAKCPSPGLGPDRIKDLMLQLL 548
Query: 533 RGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPE 592
GV LH N I+HRDLK NLL+S G LK+ DFGLAR Y + A T VVVT WYR+PE
Sbjct: 549 NGVDFLHSNRIVHRDLKPQNLLISKDGRLKLADFGLARIYSFHM-ALTTVVVTLWYRSPE 725
Query: 593 LLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWP-GYS 651
+L+ A EY T+VD+WS GCIF EL T++ LF G+SE DQ+ K+F+ +G P WP G S
Sbjct: 726 VLMQA-EYGTSVDIWSCGCIFAELFTRRALFKGSSEFDQLKKIFEVIGLPPAGDWPEGVS 902
Query: 652 ELPVVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 710
V + +F P L+ + Q DLM K L + GRRIS+ + L H Y R+
Sbjct: 903 ----VHRNSFRPTPPVPLQTLVPE-MDPQAKDLMEKMLVFKSGRRISSRESLLHPYLRD 1064
>04591
Length = 1117
Score = 195 bits (496), Expect = 5e-50, Method: Compositional matrix adjust.
Identities = 102/267 (38%), Positives = 161/267 (60%), Gaps = 7/267 (2%)
Frame = -2
Query: 460 KEGFPITSLREINTILKAQHPNIVTVREIV------VGSNMDKIYIVMNYVEHDLKSLME 513
KEGFPIT+LREI + + +H N+V ++EI Y++ Y ++DL L+
Sbjct: 1101 KEGFPITALREIKILQQLEHENVVQLQEICHTQAGPYNRYKSTFYLIFEYCDYDLAGLLN 922
Query: 514 TMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYG 573
++ F + K LM QLL G+ ++H ILHRD+K +N+LL+ G+LK+ DFGL+R +
Sbjct: 921 NLRVKFSLADKKNLMSQLLNGLFYIHTKQILHRDIKAANILLTRDGVLKLADFGLSRPWV 742
Query: 574 SPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQIN 633
K T VVT WYR PELLLG +EY +DMW VGCI E+ ++KPL G SE Q++
Sbjct: 741 KS-KRLTNRVVTLWYRPPELLLGEREYGPEIDMWGVGCIMAEMWSRKPLMQGRSEQHQLS 565
Query: 634 KVFKELGTPSEKIWPGYSELPVVKKMTFSEHPYNNLRKRFGALLSD-QGFDLMNKFLTYF 692
+ G+ + ++WPG ++L + K+ + +++R LL + +G +L++ FL
Sbjct: 564 LITDLCGSLNAEVWPGVTKLELYGKLDLPQGKPRKVKERMLDLLKNKEGAELIDIFLRLD 385
Query: 693 PGRRISAEDGLKHEYFRETPLPIDPSM 719
PG+R++ ++ L H++F PLP PS+
Sbjct: 384 PGQRMNCDNALSHDFFWVDPLP-SPSL 307
>32000
Length = 644
Score = 170 bits (431), Expect = 2e-42, Method: Compositional matrix adjust.
Identities = 79/150 (52%), Positives = 106/150 (70%)
Frame = -1
Query: 561 LKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQK 620
+K+ DFGLAR +G P++ YT V+T WYRAPE+LLG + YS VD+WS+GCIF E++T++
Sbjct: 572 MKIADFGLARVFGLPVRTYTHEVITLWYRAPEILLGCRFYSVPVDIWSLGCIFVEMMTRR 393
Query: 621 PLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKMTFSEHPYNNLRKRFGALLSDQ 680
LFPG+SEIDQ+ ++F+ LGTP EK+WPG S+LP K TF + P NL LS
Sbjct: 392 ALFPGDSEIDQLYRIFRTLGTPDEKVWPGVSKLPDYKP-TFPKWPLKNLETVVS--LSKV 222
Query: 681 GFDLMNKFLTYFPGRRISAEDGLKHEYFRE 710
G DL+ + LTY P RRISA ++H YF +
Sbjct: 221 GLDLLKRMLTYNPNRRISARSAMRHPYFND 132
>01707
Length = 757
Score = 162 bits (410), Expect = 4e-40, Method: Compositional matrix adjust.
Identities = 81/221 (36%), Positives = 138/221 (62%)
Frame = +1
Query: 420 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 479
+E+++ + +I EG+YGVV++ ++K+T ++VA+K+ ++ ++REI + + +H
Sbjct: 61 MEKYEKIGKIGEGSYGVVFKCRNKETSQLVAIKKFVESEDDPLIKKIAMREIRMLKQLKH 240
Query: 480 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLH 539
PN+V R I V ++++V +YV+H L + ++ + VK ++ Q L V H
Sbjct: 241 PNLV--RLIEVFRRKKRLHLVFDYVDHTLLNELDRYPRGLPEPMVKRIIYQTLLAVNFCH 414
Query: 540 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKE 599
+HRD+K N+L++ G +K+ DFG AR P YT V T+WYRAPELL+G +
Sbjct: 415 QYNTIHRDVKPENILITRQGQVKLCDFGFARILTGPGDEYTDYVATRWYRAPELLVGDTQ 594
Query: 600 YSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELG 640
Y VD+W++GC+F ELLT + L+PG S++DQ++ + K LG
Sbjct: 595 YGPPVDVWAIGCVFAELLTGQALWPGRSDVDQLHLIRKTLG 717
>04138
Length = 800
Score = 151 bits (381), Expect = 1e-36, Method: Compositional matrix adjust.
Identities = 72/178 (40%), Positives = 111/178 (62%), Gaps = 6/178 (3%)
Frame = +1
Query: 537 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKA---YTPVVVTQWYRAPEL 593
++H N ILHRD+K +N+L++ G+LK+ DFGLAR + L+ YT VVT WYR PEL
Sbjct: 58 YIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRPPEL 237
Query: 594 LLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSEL 653
LLG + YSTA+D W GCI E+ T+ P+ G +E +Q+ + + G+ + ++WPG ++L
Sbjct: 238 LLGDRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQNQLTLITQLCGSITPEVWPGVTQL 417
Query: 654 PVVKKM--TFSEHPYNNLRKRFGALLSD-QGFDLMNKFLTYFPGRRISAEDGLKHEYF 708
+ ++ + N +R RF +L D G DL + L P +RISA++ L H++F
Sbjct: 418 SMYHQIKGALAAGRKNIIRDRFARILKDPYGLDLFERLLKMDPSQRISADEALNHDFF 591
>01966
Length = 1735
Score = 118 bits (296), Expect(2) = 3e-28, Method: Compositional matrix adjust.
Identities = 55/175 (31%), Positives = 107/175 (61%), Gaps = 2/175 (1%)
Frame = -1
Query: 440 AKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYI 499
+ + T +A+K++++ ++G P +++REI + + +H NIV + ++++ +++++
Sbjct: 1654 CRHRATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTNIVCLEDVIMED--ERLFL 1481
Query: 500 VMNYVEHDLKSLMETMKQPFLPGE--VKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSH 557
V ++ DLK ++ + + VK+ + Q++ G+ H I+HRDLK NLL++H
Sbjct: 1480 VFEFLSMDLKMYIDKFPEGVVLDRRLVKSYVFQIVTGINFCHQRRIVHRDLKPQNLLINH 1301
Query: 558 AGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCI 612
G +K+ DFG+AR + P++AYT VVT WYRAPE+L+G + + W+ G +
Sbjct: 1300 TGAIKIADFGMARTFALPVRAYTHEVVTLWYRAPEILMGPQ---STPPXWTCGAL 1145
Score = 25.4 bits (54), Expect(2) = 3e-28, Method: Composition-based stats.
Identities = 10/13 (76%), Positives = 12/13 (92%)
Frame = -2
Query: 426 LNRIEEGTYGVVY 438
L++I EGTYGVVY
Sbjct: 1695 LSKIGEGTYGVVY 1657
Score = 97.4 bits (241), Expect = 2e-20, Method: Compositional matrix adjust.
Identities = 54/138 (39%), Positives = 80/138 (57%)
Frame = -3
Query: 596 GAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPV 655
GA +YST VD+WS+G IF ++L + P+F G+SEIDQ+ K+F+ +GTP+E+ WP + +LP
Sbjct: 1187 GASKYSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKLPA 1008
Query: 656 VKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPI 715
M F L + L S G DL+ + L P +RIS + L+H YF +
Sbjct: 1007 FNGM-FPLWKEGKLSETLTDLDS-LGLDLIERTLKCDPAQRISCKKMLQHAYFLNVDTSV 834
Query: 716 DPSMFPTWPAKSEQQRVK 733
P P+ P +S R+K
Sbjct: 833 KPVDVPS-PEQS*STRLK 783
>23319
Length = 2235
Score = 103 bits (256), Expect = 3e-22, Method: Compositional matrix adjust.
Identities = 50/117 (42%), Positives = 72/117 (61%), Gaps = 1/117 (0%)
Frame = +3
Query: 597 AKEYSTAVDMWSVGCIFGELLTQ-KPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPV 655
AK YST++DMWS GCIF EL +PLFPGN + DQ+ ++FK LGTP+E WPG ++LP
Sbjct: 18 AKMYSTSIDMWSAGCIFAELANAGRPLFPGNDDDDQLKRIFKLLGTPTEDQWPGMTQLPN 197
Query: 656 VKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETP 712
+ F + ++ L+ +G DL+ L P R+SA++ L+H YF + P
Sbjct: 198 YR--MFPMYHVTTTWQQVVPKLNSKGRDLLQCLLVCCPSDRMSADEALQHPYFADLP 362
>00300
Length = 2318
Score = 94.7 bits (234), Expect = 1e-19, Method: Compositional matrix adjust.
Identities = 66/207 (31%), Positives = 108/207 (52%), Gaps = 13/207 (6%)
Frame = -1
Query: 427 NRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKA----QHPNI 482
N+I EG +G VY A + T E++ALK +K + + LRE+ +K QH N+
Sbjct: 1640 NKIGEGQFGKVYTAVNMSTGELMALKEMKFQPND----LQQLREMCDEIKIFEGIQHENL 1473
Query: 483 VTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNW 542
V + V + D++ + M Y D ++ E K ++ +++ V HLH+N
Sbjct: 1472 VKYYGVEV--HKDEMLMFMEYC--DTGTIEEAAKMGLPEYLIRRYTREIVLAVNHLHENS 1305
Query: 543 ILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTP-------VVVTQWYRAPELLL 595
I+HRD+K +N+ L+ G +K+GDFG + + LK++T +V T Y APE+
Sbjct: 1304 IVHRDIKGANIFLTSNGHVKLGDFGCSVK----LKSHTTMPGEFHNLVGTTAYMAPEVFT 1137
Query: 596 GAKE--YSTAVDMWSVGCIFGELLTQK 620
+ Y A D+WS+GC+ E+ T K
Sbjct: 1136 QNDQGGYGRAADIWSLGCVVIEMATGK 1056
>03294
Length = 1684
Score = 87.0 bits (214), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 49/130 (37%), Positives = 73/130 (56%)
Frame = -1
Query: 604 VDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKMTFSE 663
VD+WS+G IF ++L + P+F G+SEIDQ+ K+F+ +GTP+E+ WP + +LP M F
Sbjct: 1672 VDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKLPAFNGM-FPL 1496
Query: 664 HPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSMFPTW 723
L + L S G DL+ + L P +RIS + L+H YF + P P+
Sbjct: 1495 WKEGKLSETLTDLDS-LGLDLIERTLKCDPAQRISCKKMLQHAYFLNVDTSVKPVDVPS- 1322
Query: 724 PAKSEQQRVK 733
P S R+K
Sbjct: 1321 PEHS*STRLK 1292
>18921
Length = 697
Score = 85.5 bits (210), Expect = 7e-17, Method: Compositional matrix adjust.
Identities = 57/205 (27%), Positives = 109/205 (53%), Gaps = 6/205 (2%)
Frame = +2
Query: 423 FQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNI 482
F L ++ EG+YG V+++ K+T +++A+K++ ++ + + ++EI+ + + I
Sbjct: 35 FDILGKLGEGSYGSVFKSLHKETGQVLAIKQVPVDTDLQEI----IKEISIMQQCDSKYI 202
Query: 483 VTVREIVVGS---NMDKIYIVMNYV-EHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHL 538
V GS N D ++IVM Y + +M + + E+ T++ L+G+ +L
Sbjct: 203 VKYY----GSYFKNTD-LWIVMEYCGAGSVSDIMRLRNKTLVEREIATILYYTLKGLXYL 367
Query: 539 HDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELL--LG 596
H +HRD+K N+LL++ G K+ DFG+A + + V+ T ++ APE++ +G
Sbjct: 368 HSRRKIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTPYWMAPEVIQEIG 547
Query: 597 AKEYSTAVDMWSVGCIFGELLTQKP 621
Y D+WS+G E+ KP
Sbjct: 548 ---YDCVADIWSLGITALEMAEGKP 613
>06405
Length = 1965
Score = 83.2 bits (204), Expect = 3e-16, Method: Compositional matrix adjust.
Identities = 63/205 (30%), Positives = 102/205 (49%), Gaps = 8/205 (3%)
Frame = +1
Query: 422 EFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILK-AQHP 480
E +R+ G YG VY A K+ ++IVA+K LK ++ + E I+K +HP
Sbjct: 262 EIAMKHRLGGGQYGDVYEAMWKRYNKIVAVKTLK----EDTMALNDFLEEAAIMKEMKHP 429
Query: 481 NIVTVREIVVGSNMDKIYIVMNYVEHD--LKSLMETMKQPFLPGEVKTLMIQLLRGVKHL 538
N+V + + V + YIV ++ H L L + ++ P + + Q+ G+ +L
Sbjct: 430 NLVQL--LGVCTREPPFYIVTEFMPHGNLLDYLRSSTREENGPTALMYMATQIASGMAYL 603
Query: 539 HDNWILHRDLKTSNLLLSHAGILKVGDFGLAR-----EYGSPLKAYTPVVVTQWYRAPEL 593
+HRDL N L++ + ++KV DFGLAR Y + + A P+ +W APE
Sbjct: 604 ETKNFIHRDLAARNCLVADSNMVKVADFGLARLMKDDTYTAHIGAKFPI---KW-TAPE- 768
Query: 594 LLGAKEYSTAVDMWSVGCIFGELLT 618
L +ST D+W+ G + EL T
Sbjct: 769 GLAFNRFSTRSDIWAFGVLLWELAT 843
>13592
Length = 980
Score = 82.4 bits (202), Expect = 6e-16, Method: Compositional matrix adjust.
Identities = 80/295 (27%), Positives = 138/295 (46%), Gaps = 13/295 (4%)
Frame = +2
Query: 428 RIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVRE 487
+I +G +G VY A + T E++A+K + ++ + E+ + +H N+V
Sbjct: 5 KIGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETRALKNVAEELKILEGIKHKNLVRYYG 184
Query: 488 IVVGSNMDKIYIVMNYV-EHDLKSLMETMKQPFLPGEV-KTLMIQLLRGVKHLHDNWILH 545
I V + +++ I M E L+SL+E LP + + QLL GV LH + I+H
Sbjct: 185 IEV--HREELLIFMELCSEGTLESLVELTGG--LPEALSRRFTAQLLSGVAELHKHGIVH 352
Query: 546 RDLKTSNL-LLSHAGILKVGDFGLAREYGSPLKAYTPV-------VVTQWYRAPELL--L 595
RD+KT+N+ L+ + LK+GDFG A + ++A+T V V TQ Y APE+
Sbjct: 353 RDIKTANIFLVDGSNSLKLGDFGSAVK----IQAHTTVPGELQGYVGTQAYMAPEVFTKT 520
Query: 596 GAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGY-SELP 654
+ + D+WSVGC+ E+ + K + W + S
Sbjct: 521 NSDGHGRLADIWSVGCVVVEMASGK------------------------RPWAQFDSNFQ 628
Query: 655 VVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFR 709
++ K+ E P + LS +G D ++ L + P +R+SA + L+ + +
Sbjct: 629 IMFKVGMGEKP------QAPESLSQEGHDFIDHCLQHDPKQRLSAIELLEQNFCK 775
>12721
Length = 821
Score = 81.6 bits (200), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 53/196 (27%), Positives = 106/196 (54%)
Frame = +1
Query: 428 RIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVRE 487
+I EG+ G+V A + ++ A+K++ + K++ + E+ + HPNIV +
Sbjct: 109 KIGEGSTGIVCIATSRDGRQM-AVKKMDLRKQQRRELL--FNEVVVMRDYHHPNIVEMYN 279
Query: 488 IVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRD 547
+ + D++++VM ++E + + T + ++ T+ L+ + LH N ++HRD
Sbjct: 280 SYLVN--DELWVVMEFMEGGALTDIVTNNR-MDEVQIATVCRACLKALAFLHANGVIHRD 450
Query: 548 LKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMW 607
+K+ ++LLSH G +K+ DFG + L+ +V T ++ APE ++ Y VD+W
Sbjct: 451 IKSDSILLSHDGKVKLXDFGFCAQVTQDLQKRKSLVGTPYWMAPE-VISRLPYGPEVDIW 627
Query: 608 SVGCIFGELLTQKPLF 623
S+G + E++ +P F
Sbjct: 628 SLGIMVMEMIDAEPPF 675
>01718
Length = 959
Score = 79.7 bits (195), Expect = 5e-15, Method: Compositional matrix adjust.
Identities = 60/218 (27%), Positives = 107/218 (49%), Gaps = 6/218 (2%)
Frame = +3
Query: 413 ALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREIN 472
A+ +++F C +I G + V++ + T +++ALK M + LRE+
Sbjct: 126 AVSALTRLDDFIC-EKIGAGFFSEVFKVTHRITGQVMALKMNTMTSNRHNM----LREVQ 290
Query: 473 TILKAQHPNIVTVREIVVGSNMDKIYIVMNYV-EHDLKSLMETMKQPFLPGEVKTLMIQL 531
+ + QH NI+ + V +++ + Y+ +L+ L+E + + L + L
Sbjct: 291 LLNRLQHANILRFMGVCVHEG--QLHALTEYIPSGNLEQLLEKKDEELPWTQRIQLTLGL 464
Query: 532 LRGVKHLHDNWILHRDLKTSNLLL----SHAGILKVGDFGLAREYGSPL-KAYTPVVVTQ 586
RG+ +LH +HRDL + N+L+ +H + DFGLA + PL K P V +
Sbjct: 465 ARGLDYLHSTRFIHRDLTSKNILIRREDNHGYHAVIADFGLATKIPDPLDKEKLPTVGSP 644
Query: 587 WYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFP 624
++ APE+L G Y+ D++SVG I E+ + P P
Sbjct: 645 YWMAPEVLNG-HFYNERADLFSVGIIMCEITARIPADP 755
>09606
Length = 1300
Score = 77.4 bits (189), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 82/314 (26%), Positives = 134/314 (42%), Gaps = 24/314 (7%)
Frame = -3
Query: 420 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 479
+E F + +G + ++Y+ + K T VA+ + EK K ++R + I H
Sbjct: 1118 MENFVLYEELGKGEHSIIYKGRRKGTINFVAIHCI--EKCKRPEVTNTVRMTHDI---SH 954
Query: 480 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPF-LP-GEVKTLMIQLLRGVKH 537
PN+V E SN +++V+ SL + + Q LP ++ I L+ G+ +
Sbjct: 953 PNVVQFHEWYETSN--HLWLVVELCTGG--SLADILAQDHHLPETSIRDFGIHLVTGLHY 786
Query: 538 LHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAY------------------ 579
+H IL DL+ S +LL +G+LK DFGL++ G L+
Sbjct: 785 IHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQWNIQSAEE 606
Query: 580 ----TPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKV 635
P + Y APE+ GA E S D+W++GC+F E+ + P F G + +KV
Sbjct: 605 MMKQVPTSGSPTYMAPEVFQGA-EPSIMSDLWALGCVFYEMFSGHPPFLGETYDITKDKV 429
Query: 636 FKELGTPSEKIWPGYSELPVVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGR 695
K +P LP VK S P S + +L+ L R
Sbjct: 428 LN-------KEFP----LPKVKGSRLSAKP------------SPEFLNLLESLLQKDSTR 318
Query: 696 RISAEDGLKHEYFR 709
R+S +KH +++
Sbjct: 317 RLSWASLVKHAFWQ 276
>03508
Length = 1463
Score = 76.6 bits (187), Expect = 4e-14, Method: Compositional matrix adjust.
Identities = 39/122 (31%), Positives = 72/122 (59%), Gaps = 2/122 (1%)
Frame = +1
Query: 505 EHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGI-LKV 563
EH + + + Q F +++ + +L++ + H I+HRD+K N+++ H L++
Sbjct: 820 EHVNNTDFKQLYQTFTDYDIRFYLYELMKALDFCHSMGIMHRDVKPHNVMIDHENKKLRL 999
Query: 564 GDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQK-PL 622
D+GLA E+ P Y V +++++ PELLL + Y ++DMWS+GC+F ++ +K PL
Sbjct: 1000IDWGLA-EFYHPGMEYNVRVASRYFKGPELLLDYQMYDYSLDMWSLGCMFASMIFRKEPL 1176
Query: 623 FP 624
P
Sbjct: 1177LP 1182
Score = 35.0 bits (79), Expect = 0.11, Method: Compositional matrix adjust.
Identities = 27/114 (23%), Positives = 51/114 (44%), Gaps = 12/114 (10%)
Frame = +2
Query: 607 WSVG----CIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKMTFS 662
W+ G C+ + P F G+ DQ+ ++ K LGT + ++ + + F+
Sbjct: 1118 WTCGVWAACLPA*SSGKSPFFHGHDNYDQLVRIAKVLGT--DDLYGYIEKYQIDLDPRFN 1291
Query: 663 EHPYNNLRKRF--------GALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYF 708
+ + RKR+ L+S + D ++K L Y R++A + + H YF
Sbjct: 1292 DILGRHSRKRWERFVHSENQHLISPEALDFLDKLLRYDHNERLTAREAMDHPYF 1453
>20559
Length = 430
Score = 65.9 bits (159), Expect(2) = 1e-13, Method: Compositional matrix adjust.
Identities = 31/82 (37%), Positives = 58/82 (70%)
Frame = -2
Query: 408 PKYLPALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITS 467
P +L + +++++ L +I EGTYG V++AK+++T EIVALKR++++ + EG P ++
Sbjct: 414 PTHLHSF*LKHKMQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSA 235
Query: 468 LREINTILKAQHPNIVTVREIV 489
LREI + + +H NIV + +++
Sbjct: 234 LREICLLKELKHRNIVRLHDVL 169
Score = 29.3 bits (64), Expect(2) = 1e-13, Method: Composition-based stats.
Identities = 14/36 (38%), Positives = 19/36 (52%)
Frame = -3
Query: 503 YVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHL 538
Y + DLK +T P VK+ + QLLRG+ L
Sbjct: 134 YCDQDLKKYFDTCNGEIDPDTVKSFLHQLLRGLGFL 27
>12453
Length = 680
Score = 74.3 bits (181), Expect = 2e-13, Method: Composition-based stats.
Identities = 41/100 (41%), Positives = 55/100 (55%)
Frame = +3
Query: 609 VGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKMTFSEHPYNN 668
VGCIF E+ +PLFPG++ D+++ +FK LGTP+E P S P + +
Sbjct: 6 VGCIFYEMACGRPLFPGSTVEDELHLIFKTLGTPTEDSLPSISRNPDFLALNLPHYQGEA 185
Query: 669 LRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYF 708
L L SD G DL+ KFL Y R+SA D LKH +F
Sbjct: 186 LITIAPRLDSD-GLDLLAKFLKYNAKIRVSAADSLKHSFF 302
>14420
Length = 528
Score = 73.2 bits (178), Expect = 4e-13, Method: Compositional matrix adjust.
Identities = 44/156 (28%), Positives = 90/156 (57%), Gaps = 2/156 (1%)
Frame = +2
Query: 468 LREINTILKAQHPNIVT-VREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLP-GEVK 525
+ EI + + Q+PNIV + +VG +++++VM ++ SL + + + + G++
Sbjct: 44 INEILVMRENQNPNIVNYLDSYLVG---EELWVVMEFLAGG--SLTDVVTETCMDEGQIA 208
Query: 526 TLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVT 585
+ + L+ ++ LH+N ++HRD+K+ N+LL G +K+ DFG + + +V T
Sbjct: 209 AVCRECLQALEFLHENQVIHRDIKSDNILLGMDGSVKLTDFGFCAQLSPEQSKRSTMVGT 388
Query: 586 QWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKP 621
++ APE ++ K+Y VD+WS+G + E++ +P
Sbjct: 389 PYWMAPE-VVTRKQYGPTVDIWSLGVMCIEMIEGEP 493
>15910
Length = 1361
Score = 70.9 bits (172), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 49/125 (39%), Positives = 67/125 (53%), Gaps = 3/125 (2%)
Frame = +2
Query: 531 LLRGVKHLHDNWILHRDLKTSNLL---LSHAGILKVGDFGLAREYGSPLKAYTPVVVTQW 587
+L GV+++H N ++HRDLK NLL ++ LK+ DFGL+R P + V T
Sbjct: 491 ILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLADFGLSRII-EPEVQMSTVCGTPG 667
Query: 588 YRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIW 647
Y APE+L G K Y+ +VDMWSVG I LL F +E + K+ K E+ W
Sbjct: 668 YCAPEVLKGDK-YTPSVDMWSVGVIAYILLCGYEPFFAENEFEMYRKIIKGEYKFDEEYW 844
Query: 648 PGYSE 652
SE
Sbjct: 845 SEISE 859
>26560
Length = 398
Score = 68.2 bits (165), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 37/119 (31%), Positives = 66/119 (55%), Gaps = 4/119 (3%)
Frame = -1
Query: 519 FLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKA 578
F EV+ +++ G++H+H ++++RDLK +N+LL G +++ D GLA ++ K
Sbjct: 365 FTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGLACDFSK--KR 192
Query: 579 YTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLF----PGNSEIDQIN 633
V T Y APE+L+ + Y ++ D +S GC+ +LL F G + ID++
Sbjct: 191 PHASVGTHGYMAPEVLMKGQSYDSSADWFSFGCMLYKLLKGHSPFRQHNQGQARIDRMT 15
>19761
Length = 473
Score = 65.5 bits (158), Expect = 8e-11, Method: Compositional matrix adjust.
Identities = 36/104 (34%), Positives = 60/104 (57%)
Frame = -3
Query: 537 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLG 596
H H ILHRDLK N+ ++ G +++GD GLAR+ P T V T Y +PE +L
Sbjct: 372 HTHTPVILHRDLKPQNIYVTEKGDVRLGDLGLARKLTGPADFATSQVGTIMYLSPE-ILS 196
Query: 597 AKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELG 640
+ Y++ D+WS+GC+F ++ +K G+ E+ + + + +G
Sbjct: 195 QQPYNSKSDIWSLGCVFYDITGKK----GSDEMGVMFLLVQVMG 76
>18484
Length = 635
Score = 65.5 bits (158), Expect = 9e-11, Method: Compositional matrix adjust.
Identities = 35/99 (35%), Positives = 55/99 (55%)
Frame = +1
Query: 530 QLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYR 589
++ G+ LHD I++RDLK N++L G +K+ DFG+ +E + T Y
Sbjct: 67 EIAVGLFFLHDQGIIYRDLKLDNVMLDSEGHIKIADFGMCKEGMTGDATTRTFCGTPDYI 246
Query: 590 APELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSE 628
APE++L + YS +VD W+ G + E+L +P F G E
Sbjct: 247 APEIVL-YQPYSKSVDWWAYGVLLFEMLAGQPPFDGEDE 360
>21578
Length = 524
Score = 64.3 bits (155), Expect = 2e-10, Method: Composition-based stats.
Identities = 26/33 (78%), Positives = 31/33 (93%)
Frame = +2
Query: 403 LKQELPKYLPALQGCRSVEEFQCLNRIEEGTYG 435
LK++LP YLPA+QGCR+VEEF C+NRIEEGTYG
Sbjct: 425 LKEDLPVYLPAIQGCRNVEEFHCMNRIEEGTYG 523
>27546
Length = 426
Score = 62.8 bits (151), Expect = 5e-10, Method: Composition-based stats.
Identities = 38/113 (33%), Positives = 60/113 (53%), Gaps = 2/113 (1%)
Frame = -1
Query: 460 KEGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQ-- 517
K+ FP RE+ + + HPNI+ + I+ KI+I M Y E ++ +K+
Sbjct: 348 KKFFP----RELEILTRLDHPNIIQIHSIL--QRGPKIFIFMRYAEKG--DMLSHIKKTG 193
Query: 518 PFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAR 570
P + K Q+ + +++LH + I HRDLK N+LLS +K+ DFG AR
Sbjct: 192 PIDEAQTKVWFFQMAKALQYLHSHDIAHRDLKCENILLSKRLNVKIADFGFAR 34
>03240
Length = 1683
Score = 61.6 bits (148), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 62/262 (23%), Positives = 105/262 (40%), Gaps = 48/262 (18%)
Frame = -3
Query: 423 FQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNI 482
F+ + + G +G V + T + A+K L+ + + ++ IL A+ N
Sbjct: 1285 FEKIKTLGVGAFGEVSLCRKNDTGMLYAMKTLRKSDVLKRNQVAHVKAERDIL-AEADNE 1109
Query: 483 VTVREIVVGSNMDKIYIVMNYVEH-DLKSL---METMKQPFLPGEVKTLMIQLLRGVKHL 538
V+ + + +Y VM+YV DL L ME + +P + + +L++ ++ +
Sbjct: 1108 WVVKLYYSFQDHNYLYFVMDYVPGGDLMGLLIRMEILDEPL----ARFYVAELVQAIESV 941
Query: 539 HDNWILHRDLKTSNLLLSHAGILKVGDFGL-------------------AREYGSPLKAY 579
H +HRD+K N+L+ G +K+ DFGL AR+ +K
Sbjct: 940 HRMGFIHRDIKPDNILIDRNGHIKLTDFGLCTGFRWTHNSKYYQRDGTHARQDSMEVKCQ 761
Query: 580 T-------------------------PVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFG 614
+V T Y APE+L Y++ D WSVG I
Sbjct: 760 LDEQCQCEILKPLERRRKREQRCLAHSLVGTPNYIAPEVLSRLGGYTSVCDWWSVGVILF 581
Query: 615 ELLTQKPLFPGNSEIDQINKVF 636
E+L P F N+ + KV
Sbjct: 580 EMLVGHPPFYANTPAETQYKVI 515
>14116
Length = 1017
Score = 61.6 bits (148), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 61/205 (29%), Positives = 99/205 (48%), Gaps = 14/205 (6%)
Frame = -1
Query: 429 IEEGTYGVVYRA----KDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVT 484
I +G +G V R ++K D +VA+K L +E + L+E + H N++T
Sbjct: 612 IGKGNFGCVKRGFLTLPEQKGDILVAVKTLHNNNPREIELQSFLQEALIMKDFHHSNVLT 433
Query: 485 VREIVVGSNMDKI-YIVMNYVEHD--LKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDN 541
+ I + N+D + +V+ +++H L + + QP + ++ + + RG+ +L
Sbjct: 432 LIGICL--NLDDMPLVVLPFMKHGDLLTYIRDDQHQPTIK-DLIMYGVDIARGMDYLAGL 262
Query: 542 WILHRDLKTSNLLLSHAGILKVGDFGLAR-----EYGSP--LKAYTPVVVTQWYRAPELL 594
+HRDL N +L +KV DFGLAR EY S KA PV +W L
Sbjct: 261 KFVHRDLAARNCMLDEDFHVKVADFGLARDIYEKEYYSSENKKAKLPV---KWMALESLE 91
Query: 595 LGAKEYSTAVDMWSVGCIFGELLTQ 619
G Y + D+WS G + ELLT+
Sbjct: 90 KG--NYDSKTDVWSYGVVLWELLTR 22
>30755
Length = 1137
Score = 61.2 bits (147), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 35/94 (37%), Positives = 51/94 (54%), Gaps = 3/94 (3%)
Frame = +2
Query: 530 QLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLARE---YGSPLKAYTPVVVTQ 586
+++ + +LH I++RDLK NLLL G +KV DFGL +E YG K + T
Sbjct: 56 EIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCKEDITYGRTTKTFCG---TP 226
Query: 587 WYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQK 620
Y APE +L +Y AVD W G + E++ +
Sbjct: 227 EYLAPE-VLDDNDYGRAVDWWGTGVVMYEMICGR 325
>13066
Length = 551
Score = 61.2 bits (147), Expect = 2e-09, Method: Composition-based stats.
Identities = 52/185 (28%), Positives = 87/185 (47%), Gaps = 6/185 (3%)
Frame = +3
Query: 432 GTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREIVVG 491
GT+ Y K +I+ ++ ++ ++ FP RE++ + K HP I+ + I+
Sbjct: 24 GTFNDGYGRNIKLACKIIDKEKAPVDFVEKFFP----RELDLLTKLDHPYIIQIHSIL-- 185
Query: 492 SNMDKIYIVMNYVEH-DLKSLMETMKQPFLP-GEVKTLMIQLLRGVKHLHDNWILHRDLK 549
K +I M + E DL + ++ + F+ + K Q+ + +LH + HRDLK
Sbjct: 186 QRXPKNFIFMRFAERGDLLTYIQEVG--FVKEKQAKIWFYQMTTALNYLHSYDVAHRDLK 359
Query: 550 TSNLLLSHAGILKVGDFGLA----REYGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVD 605
N+LLS +K+ DFG A E G + T + Y APE++ GA D
Sbjct: 360 CENILLSSHFNVKLADFGFACACITESGEKYMSRT-YCGSAAYAAPEIVYGAPYAPKVAD 536
Query: 606 MWSVG 610
WS+G
Sbjct: 537 AWSLG 551
>13212
Length = 1067
Score = 61.2 bits (147), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 46/206 (22%), Positives = 93/206 (45%), Gaps = 4/206 (1%)
Frame = -1
Query: 508 LKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFG 567
L S+M +++P ++ + ++ + LH + ++HRD+K N+LL+ G +K+ DFG
Sbjct: 1022 LDSIMVDLEKPMTEAQICYVCHEMCMALDFLHRHHVIHRDIKAGNVLLTIDGEVKLADFG 843
Query: 568 LAREYGSPLKAYTPVVVTQWYRAPELLLGA----KEYSTAVDMWSVGCIFGELLTQKPLF 623
++ + + + T ++ APE++L Y D+WS+G E
Sbjct: 842 VSAKNTQTQQKRDTFIGTPYWMAPEVVLCETLKDTPYDFKADIWSLGVTLIE-------- 687
Query: 624 PGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKMTFSEHPYNNLRKRFGALLSDQGFD 683
F ++ P++++ P + V+ K+ S+ P K++ L D
Sbjct: 686 ------------FAQIEPPNKEMHP----MRVLIKIHKSDPPTLEKPKKWTKLFK----D 567
Query: 684 LMNKFLTYFPGRRISAEDGLKHEYFR 709
+ K L P R +A + L+H + +
Sbjct: 566 FIAKCLVKDPNLRPTAAELLEHPFMK 489
>28638
Length = 1458
Score = 60.8 bits (146), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 33/81 (40%), Positives = 51/81 (62%), Gaps = 2/81 (2%)
Frame = -1
Query: 543 ILHRDLKTSNLLLSHA--GILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEY 600
I+H DLK N+LL + +K+ DFG + + G + Y + +++YR+PE+LLG Y
Sbjct: 768 IIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQY---IQSRFYRSPEVLLGVP-Y 601
Query: 601 STAVDMWSVGCIFGELLTQKP 621
A+DMWS+GCI E+ T +P
Sbjct: 600 DLAIDMWSLGCILVEMHTGEP 538
Score = 30.0 bits (66), Expect = 3.9, Method: Compositional matrix adjust.
Identities = 15/52 (28%), Positives = 22/52 (42%), Gaps = 5/52 (9%)
Frame = -2
Query: 600 YSTAVDMWSVGC-----IFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKI 646
Y W + C + PLF G++E DQ+ K+ + LG P I
Sbjct: 617 YXXCPMTWPLTCGXWAVYWWRCTXGNPLFAGSNEFDQMMKIVEVLGVPPRHI 462
>26909
Length = 394
Score = 60.1 bits (144), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 38/119 (31%), Positives = 57/119 (47%), Gaps = 16/119 (13%)
Frame = +2
Query: 612 IFGELLTQKPLFPGNSEI---------DQINKVFKELGTPSEKIWPGYSELPVVKKMT-- 660
IF ELLT +P+F E DQ++++F +G P EK W +P +++T
Sbjct: 2 IFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFPQEKDWEDIRRMPEHQQLTKD 181
Query: 661 FSEHPYNNLR-----KRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLP 714
F Y N ++ + F L+ K LT P +RI++E +K YF E PLP
Sbjct: 182 FKRSSYVNCNLMKYMEKHKVKADSKAFHLLQKLLTMDPVKRITSEQAMKDPYFLEEPLP 358
>19094
Length = 898
Score = 58.9 bits (141), Expect = 8e-09, Method: Compositional matrix adjust.
Identities = 31/105 (29%), Positives = 58/105 (55%), Gaps = 2/105 (1%)
Frame = +1
Query: 508 LKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFG 567
+ +M + + E+ T++ L+G+ +LH +HRD+K N+LL++ G K+ DFG
Sbjct: 16 VSDIMRLRNKTLVEREIATILYYTLKGL*YLHSRRKIHRDIKAGNILLNNEGHAKLADFG 195
Query: 568 LAREYGSPLKAYTPVVVTQWYRAPELL--LGAKEYSTAVDMWSVG 610
+A + + V+ T ++ APE++ +G Y D+WS+G
Sbjct: 196 VAGQLTDTMAKRNTVIGTPYWMAPEVIQEIG---YDCVADIWSLG 321
>21808
Length = 1011
Score = 58.2 bits (139), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 56/201 (27%), Positives = 96/201 (47%), Gaps = 14/201 (6%)
Frame = +1
Query: 449 VALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDL 508
VA+K LK P L E + K +HP ++ + V + D I+I+ +++
Sbjct: 28 VAIKTLKSGTMD---PKDFLAEAQIMKKLRHPKLIQL--YAVCTQDDPIFIITELMKNG- 189
Query: 509 KSLMETMKQPFLPGEVKTLMI--------QLLRGVKHLHDNWILHRDLKTSNLLLSHAGI 560
SL+E FL G+ + L + Q+ G+ +L +HRDL N+L+S
Sbjct: 190 -SLLE-----FLQGKGRVLKLPALIDIGAQIACGMAYLESQNYIHRDLAARNILVSDNNT 351
Query: 561 LKVGDFGLAR-----EYGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGE 615
+K+ DFGLAR EY + + A P+ +W APE ++ D+WS G + E
Sbjct: 352 VKIADFGLARVIKEDEYEARVGARFPI---KW-TAPE-AANYNRFTIKSDVWSFGILLTE 516
Query: 616 LLTQKPL-FPGNSEIDQINKV 635
+T + +PG + + +++V
Sbjct: 517 TVTYGRVPYPGMTNAEVLHQV 579
>11185
Length = 473
Score = 56.6 bits (135), Expect = 4e-08, Method: Compositional matrix adjust.
Identities = 35/117 (29%), Positives = 56/117 (47%), Gaps = 22/117 (18%)
Frame = +1
Query: 524 VKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAY---- 579
++ I L+ G+ ++H IL DL+ S +LL +G+LK DFGL++ G L+
Sbjct: 7 IRDFGIHLVTGLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKF 186
Query: 580 ------------------TPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLT 618
P + Y APE+ GA E S D+W++GC+F E+ +
Sbjct: 187 AEAGDQWNIQSAEEMMKQVPTSGSPTYMAPEVFQGA-EPSIMSDLWALGCVFYEMFS 354
>19301
Length = 712
Score = 55.8 bits (133), Expect = 7e-08, Method: Compositional matrix adjust.
Identities = 43/149 (28%), Positives = 75/149 (50%), Gaps = 2/149 (1%)
Frame = +2
Query: 421 EEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHP 480
E L + G G V+ K E VA+K+++ KE + I +LR++N HP
Sbjct: 305 ESITDLEWLGSGAQGAVFLGK--LCAEEVAVKKVRDIKETD---IRNLRKLN------HP 451
Query: 481 NIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMK--QPFLPGEVKTLMIQLLRGVKHL 538
NI++ + + + I+M Y + L E ++ + P V Q+ G+ +L
Sbjct: 452 NIISFKGVC--TQAPCYCIIMEYCPYG--QLYEVLRDGKEIPPALVLDWSKQIASGMNYL 619
Query: 539 HDNWILHRDLKTSNLLLSHAGILKVGDFG 567
H + I+HRDLK+ N+L++ ++K+ DFG
Sbjct: 620 HSHKIIHRDLKSPNVLVAKNDVVKISDFG 706
>27405
Length = 532
Score = 55.8 bits (133), Expect = 7e-08, Method: Compositional matrix adjust.
Identities = 28/87 (32%), Positives = 51/87 (58%)
Frame = -3
Query: 519 FLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKA 578
F EV+ +++ G++H+H ++++RDLK +N+LL G +++ D GLA ++ K
Sbjct: 263 FTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGLACDFSK--KK 90
Query: 579 YTPVVVTQWYRAPELLLGAKEYSTAVD 605
V T Y APE+L+ + Y ++ D
Sbjct: 89 PHASVGTHGYMAPEVLMKGQAYDSSAD 9
>18287
Length = 678
Score = 55.8 bits (133), Expect = 7e-08, Method: Composition-based stats.
Identities = 35/119 (29%), Positives = 53/119 (44%), Gaps = 8/119 (6%)
Frame = -3
Query: 600 YSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKM 659
Y ++D+WSVGCIF ELL+++ LF + Q++ + +GTP + E
Sbjct: 673 YDYSIDIWSVGCIFAELLSRRILFQAQGPVQQLDMIINLVGTPRPEDMERACE------- 515
Query: 660 TFSEHPYNNLRKRFGALL--------SDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 710
H N +R L + + L+ + L P RISAE+ L H Y E
Sbjct: 514 GARNHILNQPFRRQNLLTLYNLSPHATHEAVRLLTRMLILNPKNRISAEEALSHPYLDE 338
>07940
Length = 1336
Score = 55.5 bits (132), Expect = 8e-08, Method: Compositional matrix adjust.
Identities = 34/112 (30%), Positives = 57/112 (50%), Gaps = 6/112 (5%)
Frame = -3
Query: 513 ETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLARE- 571
+ M + P ++ + Q+ RG+++L +HRDL N+L++ +LK+ DFGL R
Sbjct: 374 QDMLKMLTPKDLISYAYQVARGMEYLASKQCIHRDLAARNVLVAEEYVLKIADFGLTRNL 195
Query: 572 -----YGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLT 618
Y PV +W APE L ++Y++ D+WS G + E+ T
Sbjct: 194 QQFDYYRKTTDGRLPV---KW-MAPEALFD-RKYTSKSDVWSYGVLLWEIFT 54
>24241
Length = 413
Score = 55.5 bits (132), Expect = 9e-08, Method: Compositional matrix adjust.
Identities = 25/84 (29%), Positives = 54/84 (64%)
Frame = -2
Query: 426 LNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTV 485
L++I EGTYGVVY+ + + T +A+K++++ ++G P +++REI + + +H +
Sbjct: 328 LSKIGEGTYGVVYKCRHRATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTQXLVC 149
Query: 486 REIVVGSNMDKIYIVMNYVEHDLK 509
E V+ + +++++V ++ DLK
Sbjct: 148 LEDVIMED-ERLFLVFEFLSMDLK 80
>26711
Length = 405
Score = 55.1 bits (131), Expect = 1e-07, Method: Composition-based stats.
Identities = 39/111 (35%), Positives = 61/111 (54%), Gaps = 6/111 (5%)
Frame = -2
Query: 530 QLLRGVKHLHDNWILHRDLKTSNLLLSHAGI--LKVGDFGLAREYGSPLKAY----TPVV 583
Q+L ++H+H ++H DLK SNLLLS + +++ DFGLAR+ P + + TP
Sbjct: 392 QVLDILQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARKLYPPQETFLNHGTP-- 219
Query: 584 VTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINK 634
+ +PE L K STA D+W VG + LL+ + F +S + + K
Sbjct: 218 ---GFTSPE-ALDVKPISTASDVWGVGVLAYILLSGQSPFQADSATESLKK 78
>28157
Length = 400
Score = 55.1 bits (131), Expect = 1e-07, Method: Composition-based stats.
Identities = 44/129 (34%), Positives = 67/129 (51%), Gaps = 8/129 (6%)
Frame = +3
Query: 449 VALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSNMDK-IYIVMNYVEHD 507
VA+KR++ E+EK+ F ++E+ + + HPNIV + G+ D + +VM Y E
Sbjct: 9 VAVKRIESEQEKKSF----MQELKQLSRVSHPNIVCL----YGACRDHPVCLVMEYAEGG 164
Query: 508 --LKSLMETMKQP-FLPGEVKTLMIQLLRGVKHLHD---NWILHRDLKTSNLLLSHAGI- 560
L + QP + ++Q GV++LH ++HRDLK NLLL G
Sbjct: 165 SLYNVLHGSGPQPQYTAAHAMNWLLQCALGVEYLHGMKPKALIHRDLKPPNLLLIQCGTK 344
Query: 561 LKVGDFGLA 569
LK+ DFG A
Sbjct: 345 LKICDFGTA 371
>31489
Length = 329
Score = 54.7 bits (130), Expect = 2e-07, Method: Composition-based stats.
Identities = 28/81 (34%), Positives = 50/81 (61%), Gaps = 4/81 (4%)
Frame = +3
Query: 478 QHPNIVTVREIVVGSN----MDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLR 533
+H NI+++REI+ + I++V + +E DL ++ + QP ++ + Q+LR
Sbjct: 24 KHDNIISIREILKPKDSYHDFKDIHVVFDLMESDLHRIIYS-DQPLTEEHIRYFLYQILR 200
Query: 534 GVKHLHDNWILHRDLKTSNLL 554
G+K++H ++HRDLK SNLL
Sbjct: 201 GLKYIHSANVVHRDLKPSNLL 263
>17253
Length = 483
Score = 53.1 bits (126), Expect = 4e-07, Method: Composition-based stats.
Identities = 44/140 (31%), Positives = 67/140 (47%), Gaps = 14/140 (10%)
Frame = -1
Query: 457 EKEKEGFPITSLREINTILK-AQHPNIVTVREIVVGSNMDKIYIVMNYVEH-DLKSLMET 514
+ EK F LRE++ + K +HPN+V+ S D I+M + H DL S +
Sbjct: 426 DAEKSEF----LRELSIMRKLPRHPNVVSFMGCCTMS--DPALILMEFCCHGDLLSFLRK 265
Query: 515 MKQP----FLPGEVKTLM--------IQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILK 562
++P FL L + + RG+ H+ +N I+HRD+ N+L+S + K
Sbjct: 264 -RRPDRTVFLTSTANDLTARDFFSFALHVARGMAHVANNKIVHRDVAARNVLISERNVCK 88
Query: 563 VGDFGLAREYGSPLKAYTPV 582
V DFGL+R G Y V
Sbjct: 87 VSDFGLSRRVGDQNDVYEIV 28
>04852
Length = 1462
Score = 52.8 bits (125), Expect = 6e-07, Method: Compositional matrix adjust.
Identities = 30/90 (33%), Positives = 48/90 (53%)
Frame = +1
Query: 529 IQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWY 588
Q+ RG++ L +HRDL N+L++ +LK+ DFGL+R K + +W
Sbjct: 346 FQIARGMEFLASRKCIHRDLAARNVLVTEEHVLKIADFGLSRTGDYYKKRSGGRLPVKWM 525
Query: 589 RAPELLLGAKEYSTAVDMWSVGCIFGELLT 618
APE L + Y+T D+WS G + E+ +
Sbjct: 526 -APEALFDMR-YTTKSDVWSFGVVLWEIFS 609
>18401
Length = 463
Score = 51.6 bits (122), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 39/144 (27%), Positives = 66/144 (45%), Gaps = 14/144 (9%)
Frame = -3
Query: 579 YTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKE 638
++ +V T+ YRAPE++L +S D+WSVGCI EL T LF + + + + +
Sbjct: 461 HSTIVSTRHYRAPEVILELG-WSHPCDVWSVGCIMFELYTGYTLFQTHDNKEHLAMMERI 285
Query: 639 LGTPSEKI--------WPGYSELPVVKKMTFSEHPYNNLRKRFGALLS------DQGFDL 684
LG+ ++ + + L V ++ + + + N + + Q FDL
Sbjct: 284 LGSLPYRMAKKTKKQKYFHHGRLDVPERSSMARYVRENTKPLLRYVKDRENKDHQQLFDL 105
Query: 685 MNKFLTYFPGRRISAEDGLKHEYF 708
M K L Y R S L+H +F
Sbjct: 104 MKKLLAYEASSRYSLLQALQHPFF 33
>00715
Length = 1788
Score = 51.6 bits (122), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 48/177 (27%), Positives = 84/177 (47%), Gaps = 29/177 (16%)
Frame = +1
Query: 478 QHPNIVTVREIVVGSNM-----DKIYIVMNYV-EHDLKSLMETMKQPFLPGEVKTLMIQL 531
+H N+V++ +G+ D ++ M YV +L++++ +Q +L +Q+
Sbjct: 100 RHVNVVSI----LGATSLHRFEDGAWLAMEYVGPLNLQTILNDHQQDIDSSMRLSLALQM 267
Query: 532 LRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREY---------------GSPL 576
RG+ +LH I+H DLK +N LL+ L++ DFG + G+ L
Sbjct: 268 ARGLHYLHSINIVHLDLKPANCLLTRDLKLRIADFGCCHQLTPTGLDMGEREGGMAGNEL 447
Query: 577 KAYTPV--------VVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPG 625
+ TPV T YRAPELL G + S D++S+G ++ T++ + G
Sbjct: 448 E-LTPVQGAWKNELAGTLAYRAPELLKGLQP-SVRSDVYSLGITLWQMCTRQGPYEG 612
>21079
Length = 878
Score = 50.8 bits (120), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 34/91 (37%), Positives = 50/91 (54%), Gaps = 2/91 (2%)
Frame = +1
Query: 530 QLLRGVKHLHDNWILHRDLKTSNLLL--SHAGILKVGDFGLAREYGSPLKAYTPVVVTQW 587
Q+ GV ++H ILH DLK N+L ++ +K+ DFGLAR Y P + + T
Sbjct: 151 QICSGVGYMHTQSILHLDLKPENVLCVSDNSNQIKIIDFGLARFY-KPGDSLQVLFGTPE 327
Query: 588 YRAPELLLGAKEYSTAVDMWSVGCIFGELLT 618
+ APE ++ E + DMWS+G I LL+
Sbjct: 328 FIAPE-VVNYDEINFTTDMWSIGVICYILLS 417
>12672
Length = 773
Score = 50.8 bits (120), Expect = 2e-06, Method: Composition-based stats.
Identities = 31/89 (34%), Positives = 50/89 (56%), Gaps = 4/89 (4%)
Frame = +3
Query: 534 GVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREY----GSPLKAYTPVVVTQWYR 589
G+++L+DN +HRD+KT+N+LL KVGDF G ++ + V+ T Y
Sbjct: 27 GIQYLNDNGHVHRDIKTANILLDSEYTAKVGDFATVVSAPSGEGKTVQNASVVIGTAAYL 206
Query: 590 APELLLGAKEYSTAVDMWSVGCIFGELLT 618
APE + + ST +D +S G + E++T
Sbjct: 207 APEAI--HFDVSTKLDSYSFGVVLLEVIT 287
>16003
Length = 926
Score = 50.4 bits (119), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 35/99 (35%), Positives = 51/99 (51%)
Frame = -1
Query: 616 LLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKMTFSEHPYNNLRKRFGA 675
LL + P PG++++DQ+ K+F LGTP+E WP + LP + F L++ F A
Sbjct: 926 LLIRLPFLPGDTDLDQLGKIFNMLGTPTETEWPAVTSLP--DYIQFKHCQKQPLKEIFTA 753
Query: 676 LLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLP 714
D +L++K L P R +A LK YF P P
Sbjct: 752 -AGDDLLELLDKLLAMNPLHRCTATQALKMPYFSNKPYP 639
>00392
Length = 668
Score = 50.1 bits (118), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 46/163 (28%), Positives = 74/163 (45%), Gaps = 6/163 (3%)
Frame = +3
Query: 478 QHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTL---MIQLLRG 534
QHPNIV + N +++ E ++T + F VK L Q+L+G
Sbjct: 105 QHPNIVRFFDYWEEHNHRNRKVIILVTELMTSGTLKTYLKRFKKPNVKILKNWCRQVLKG 284
Query: 535 VKHLHDNW--ILHRDLKTSNLLLSH-AGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAP 591
+ LH ++HRDLK N+ ++ G +K+GD GLA V+ T + AP
Sbjct: 285 LYFLHTRTPPVIHRDLKCDNIFITGPTGSVKIGDLGLATLKNQSFAK--SVIGTPEFMAP 458
Query: 592 ELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINK 634
E+ + Y AVD+++ G E+ + + + S QI K
Sbjct: 459 EMY--EEHYDEAVDVYAFGMCMLEMASSEYPYSECSNAAQIYK 581
>12786
Length = 460
Score = 50.1 bits (118), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 38/117 (32%), Positives = 58/117 (49%), Gaps = 23/117 (19%)
Frame = -3
Query: 530 QLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLA----REYGSPLKAYTPVVVT 585
++LR VK LH+ ++H DLK +N +L AG LK+ DFG+A ++ S LK V T
Sbjct: 386 EMLRAVKALHNEGVIHSDLKPANFMLV-AGNLKLIDFGIANTLQQDKTSVLK--DSRVGT 216
Query: 586 QWYRAPELLLGAKE-----------------YSTAV--DMWSVGCIFGELLTQKPLF 623
Y +PE ++ A + Y V D+WS+GCI ++ + F
Sbjct: 215 PSYMSPEAIMAACDDSADDSMEEDGHRTKPKYKVGVRSDVWSLGCILYNMVYGRTPF 45
>17300
Length = 480
Score = 49.3 bits (116), Expect = 5e-06, Method: Composition-based stats.
Identities = 31/90 (34%), Positives = 51/90 (56%), Gaps = 5/90 (5%)
Frame = +1
Query: 534 GVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLK--AYTP---VVVTQWY 588
G+ L D +HRDL N+L++ + KV DFGL+RE S AYT + +W
Sbjct: 10 GMGXLADMGYVHRDLAARNILVNEILVCKVADFGLSREIESDTTEGAYTTKGGKIPVRW- 186
Query: 589 RAPELLLGAKEYSTAVDMWSVGCIFGELLT 618
APE + +++++A D+WS G + E+++
Sbjct: 187 TAPE-AIAYRKFTSASDVWSFGVVMWEVMS 273
>31885
Length = 529
Score = 47.4 bits (111), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 46/161 (28%), Positives = 73/161 (45%), Gaps = 4/161 (2%)
Frame = -2
Query: 471 INTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQ 530
++ + + HP +V + D +V ++ DL+ M+ + F VK + Q
Sbjct: 519 VDMLTRLDHPFLVNLW-YAFQDEEDLFMVVDLFLGGDLRYHMQQ-EVSFREDCVKFYLCQ 346
Query: 531 LLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRA 590
L + +L I+HRD+K N+LL G V DF +A + A T T+ Y A
Sbjct: 345 LALVLDYLRSQKIVHRDIKPDNILLDEQGHCHVTDFNIATQLEDDELA-TSTSGTRPYMA 169
Query: 591 PELLLGA----KEYSTAVDMWSVGCIFGELLTQKPLFPGNS 627
PE+ A + Y VD WS+G ELL ++ F +S
Sbjct: 168 PEVYGVAINERRGYGFPVDWWSLGVSLFELLKKRRPFSVHS 46
>11780
Length = 1713
Score = 45.8 bits (107), Expect = 7e-05, Method: Compositional matrix adjust.
Identities = 51/202 (25%), Positives = 98/202 (48%), Gaps = 4/202 (1%)
Frame = +3
Query: 429 IEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREI 488
I +G +G VY+ + + VA+K+LK +K+ + L+E + + +H N+V + +
Sbjct: 621 IGKGDFGDVYKGMYR--GQPVAIKQLK---DKDRGEQSFLQEASVMTSLRHDNLVRLIGV 785
Query: 489 VVGSNMDKIYIVMNYV-EHDLKSLMETMKQPFLPGEVK-TLMIQLLRGVKHLHDNWILHR 546
V+G + I++V ++ + +L + + + + + + +++L ++HR
Sbjct: 786 VLG---ETIFLVTEFMGKGNLVEYLRSRGRSVITKKDQINFATDTCAAMEYLESKRLVHR 956
Query: 547 DLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEY--STAV 604
DL N+L+ G KV DFGLA+ +G + T V + APE L K + V
Sbjct: 957 DLAARNVLVHDDGKAKVSDFGLAK-FGDF--SQTSVKFPIKWTAPEALRENKIH*QVRHV 1127
Query: 605 DMWSVGCIFGELLTQKPLFPGN 626
++W + + G LL P N
Sbjct: 1128ELWHI--VMGNLLLWSSALP*N 1187
>05084
Length = 1324
Score = 45.1 bits (105), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 28/92 (30%), Positives = 43/92 (46%), Gaps = 4/92 (4%)
Frame = +2
Query: 623 FPGNSEIDQINKVFKELGTPS----EKIWPGYSELPVVKKMTFSEHPYNNLRKRFGALLS 678
PG+S +DQ+ ++ K LGTP+ ++ P YSE K HP+ K F
Sbjct: 2 LPGDSGVDQLVEIIKVLGTPTREQIREMNPNYSEF---KFPQIKAHPWT---KVFRPRTP 163
Query: 679 DQGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 710
+ L+++ L Y P RI + H +F E
Sbjct: 164 PEAIQLVSRLLEYTPSARIQPMEACAHAFFDE 259
>20640
Length = 1492
Score = 44.3 bits (103), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 26/79 (32%), Positives = 40/79 (50%), Gaps = 4/79 (5%)
Frame = +1
Query: 544 LHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYT----PVVVTQWYRAPELLLGAKE 599
+HRDL T N L+ H ++K+ DFGLAR S + Y + +W +L +
Sbjct: 10 VHRDLATRNCLVGHDLVVKISDFGLARSVHS-VDYYRGSEHDAIPIRWMPLEAILYN--K 180
Query: 600 YSTAVDMWSVGCIFGELLT 618
+ST D+WS G + E+
Sbjct: 181 FSTQSDVWSFGVVLWEIFA 237
>07836
Length = 1478
Score = 43.5 bits (101), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 53/190 (27%), Positives = 85/190 (44%), Gaps = 20/190 (10%)
Frame = -1
Query: 447 EIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIV--TVREIVVGSNMDKIYIVMNYV 504
E VA+K +E F T L + T+L +H NI+ +I + +++++ +Y
Sbjct: 1475 ENVAVKIFFTTEEASWFRETELYQ--TVL-LRHENILGFIAADIKGTGSWTQLFLITDY- 1308
Query: 505 EHDLKSLMETMKQPFL-PGEVKTLMIQLLRGVKHLHDNW--------ILHRDLKTSNLLL 555
H+ SL + + L E+ L + G+ HLH I HRD+K+ N+L+
Sbjct: 1307 -HENGSLHDYLLSRVLDSSEMLALAHSAICGLAHLHIEIFGTRGKPAIAHRDIKSKNILV 1131
Query: 556 SHAGILKVGDFGLAREYGSPLK----AYTPVVVTQWYRAP---ELLLGAKEYST--AVDM 606
G + D GLA Y S A P T+ Y AP E+LL K + DM
Sbjct: 1130 KKNGTCCIADLGLAVRYISESNEVDVAPNPRQGTKRYMAPEVLEMLLNVKNFDAFKQADM 951
Query: 607 WSVGCIFGEL 616
++ G + E+
Sbjct: 950 YAFGLVMWEI 921
>17975
Length = 449
Score = 43.5 bits (101), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 35/146 (23%), Positives = 67/146 (45%), Gaps = 10/146 (6%)
Frame = +3
Query: 434 YGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSN 493
+ VV A+ T E VA+K + K E +E+ + QHPN+V + E++
Sbjct: 6 FAVVKLARHVFTGEKVAVKVIDKTKLDEVSRSHLFQEVRCMKLVQHPNVVRLYEVI--DT 179
Query: 494 MDKIYIVM---------NYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWIL 544
K+Y+++ +Y+ L E + + + Q++ + + H ++
Sbjct: 180 QTKLYLILELGDGGDMYDYIMRHSGGLEEKLAKRYFR--------QIVEAISYCHKLHVV 335
Query: 545 HRDLKTSNLLLSHA-GILKVGDFGLA 569
HRDLK N++ G++K+ DFG +
Sbjct: 336 HRDLKPENVVFFEKPGLVKLTDFGFS 413
>21433
Length = 590
Score = 42.0 bits (97), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 33/94 (35%), Positives = 50/94 (53%)
Frame = +2
Query: 528 MIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQW 587
+ QL +++ H ++HRD+K NLLL G LK+ DFG + +P T + T
Sbjct: 185 IYQLSSALEYCHYRKVIHRDIKPENLLLGLKGDLKIADFGWSVH--APSSRRTTMCGTLD 358
Query: 588 YRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKP 621
Y PE++ G K + VD+WS+G + E L P
Sbjct: 359 YLPPEMVEG-KTHDENVDLWSLGVLCYEFLVGTP 457
>07291
Length = 833
Score = 41.6 bits (96), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 28/96 (29%), Positives = 50/96 (52%), Gaps = 6/96 (6%)
Frame = +1
Query: 530 QLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGS--PLKAYT----PVV 583
Q+ G+ +L + ++HR+L N +++ G L++ D+G+ GS P YT P
Sbjct: 73 QIADGMAYLQEVKVVHRNLAARNCIVTEDGRLQLSDYGVT---GSLFPQSYYTADDSPAR 243
Query: 584 VTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQ 619
+ APE + +S+ D+W+ G + ELLT+
Sbjct: 244 DLVKWMAPE-TIDNFHFSSKSDVWAFGVVLWELLTR 348
>15549
Length = 470
Score = 40.4 bits (93), Expect = 0.003, Method: Composition-based stats.
Identities = 18/54 (33%), Positives = 35/54 (64%), Gaps = 1/54 (1%)
Frame = -1
Query: 407 LPKYLPALQ-GCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKE 459
LP P+ + R +EF+C+ ++ +G YG+V+RAK+K ++ A+KR+ + +
Sbjct: 263 LPDKAPSAEFKSRFADEFECIEQMGKGGYGIVFRAKNKVDEQEYAVKRIALPSD 102
>02638
Length = 1490
Score = 39.3 bits (90), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 18/50 (36%), Positives = 30/50 (60%)
Frame = +1
Query: 588 YRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFK 637
+ APE+L G + Y A D+WSVGC+ E+ T +P + + + + +FK
Sbjct: 34 FMAPEVLRG-ESYGRACDVWSVGCVMIEMCTCRPPWNSHDISNHLALIFK 180
>14477
Length = 493
Score = 38.9 bits (89), Expect = 0.008, Method: Compositional matrix adjust.
Identities = 41/147 (27%), Positives = 70/147 (47%), Gaps = 4/147 (2%)
Frame = -1
Query: 428 RIEEGTYGVVYRAKDKKTD-EI-VALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTV 485
++ G +G V + + D EI VA+K LK ++E + K H +IV +
Sbjct: 469 KLGAGNFGSVMKGVCRLDDREIPVAIKVLKNADLDPSVQSELIKEAEVMKKMDHMHIVRL 290
Query: 486 REIVVGSNMDKIYIVMNYVEHDLKSLMETM-KQPFLP-GEVKTLMIQLLRGVKHLHDNWI 543
+ G M +V+ + L L + + K LP + LM Q+ +G+++L N
Sbjct: 289 IGLCEGETM---MLVLELAK--LGPLNKFLPKNKHLPLWNILELMWQVSQGMEYLEANKF 125
Query: 544 LHRDLKTSNLLLSHAGILKVGDFGLAR 570
+HRDL N+LL K+ DFG+++
Sbjct: 124 VHRDLAARNILLCDEHFAKISDFGMSK 44
>26009
Length = 886
Score = 32.0 bits (71), Expect(2) = 0.008, Method: Compositional matrix adjust.
Identities = 12/33 (36%), Positives = 22/33 (66%)
Frame = +3
Query: 523 EVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLL 555
E K++M QL+ + +H ++HRD+K N+L+
Sbjct: 714 EAKSVMKQLVSALDFMHSKQLVHRDIKPENVLI 812
Score = 25.8 bits (55), Expect(2) = 0.008, Method: Compositional matrix adjust.
Identities = 23/93 (24%), Positives = 35/93 (37%), Gaps = 5/93 (5%)
Frame = +2
Query: 421 EEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREIN-----TIL 475
E + + GTYG V A+ + T VALK L T LRE +
Sbjct: 416 EHYDVCKELGRGTYGKVVLARCRHTGTQVALKLLPKS-------CTKLREFQREFQLSYF 574
Query: 476 KAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDL 508
+ H NI+ + + ++ + V DL
Sbjct: 575 LSPHANIIDTYNVAFQTRSSYVFAQEHAVLGDL 673
>37602
Length = 804
Score = 38.9 bits (89), Expect = 0.008, Method: Compositional matrix adjust.
Identities = 20/72 (27%), Positives = 39/72 (54%)
Frame = -1
Query: 495 DKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLL 554
+K++I M Y + + P ++ + + L+G+ +LH +HRD+K +N+L
Sbjct: 300 EKLWIAMEYCGGGSMQDIYHVTGPLTEPQIAFVCRETLKGLHYLHRRGKMHRDIKGANIL 121
Query: 555 LSHAGILKVGDF 566
L+ G +K+ DF
Sbjct: 120 LTEEGDVKLADF 85
Score = 28.9 bits (63), Expect = 9.3, Method: Compositional matrix adjust.
Identities = 13/36 (36%), Positives = 21/36 (58%)
Frame = -2
Query: 406 ELPKYLPALQGCRSVEEFQCLNRIEEGTYGVVYRAK 441
E K +Q +++F+ + R+ GTYG VY+AK
Sbjct: 554 EYKKMQADIQRRNPLDDFELIQRVGSGTYGDVYKAK 447
>16708
Length = 1397
Score = 38.9 bits (89), Expect = 0.009, Method: Compositional matrix adjust.
Identities = 16/52 (30%), Positives = 31/52 (59%)
Frame = -1
Query: 521 PGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREY 572
P V + Q + ++H+H+ ++H D+K N+L+ G K+ D+G+A+ Y
Sbjct: 1097 PAMVCCIAGQXVCALEHIHELGVVHMDVKADNVLVDAHGNCKLTDYGIAQLY 942
>18481
Length = 437
Score = 38.1 bits (87), Expect = 0.014, Method: Compositional matrix adjust.
Identities = 24/77 (31%), Positives = 38/77 (49%), Gaps = 3/77 (3%)
Frame = -1
Query: 499 IVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLS-- 556
+VM + L+ L K+ F + + QLL ++ +H +HRDLK N L+
Sbjct: 266 LVMELLGPSLEELFVICKRRFTLKTILMVSDQLLSRLEFIHQKCFIHRDLKPDNFLMGLG 87
Query: 557 -HAGILKVGDFGLAREY 572
H L + DFGL++ Y
Sbjct: 86 RHCHRLYIIDFGLSKRY 36
>13078
Length = 773
Score = 38.1 bits (87), Expect = 0.015, Method: Compositional matrix adjust.
Identities = 31/125 (24%), Positives = 59/125 (47%), Gaps = 14/125 (11%)
Frame = -1
Query: 600 YSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKI--------WPGYS 651
+S D+WS+GCI EL T LF + + + + + LG+ ++ + +
Sbjct: 746 WSQPCDVWSIGCIMFELYTGYTLFQTHDNKEHLAMMERILGSLPYRMAKKTKKQKYFYHG 567
Query: 652 ELPVVKKMTFSEHPYNNLR--KRFGALLSD----QGFDLMNKFLTYFPGRRISAEDGLKH 705
L +K + + +N++ +R+ + Q FDLM+K L+Y R S ++H
Sbjct: 566 RLDWDEKSSAGRYVRDNVKPLRRYVKDPDNEDHQQLFDLMDKMLSYEVSTRYSLRQAMRH 387
Query: 706 EYFRE 710
+FR+
Sbjct: 386 PFFRK 372
>00486
Length = 797
Score = 35.4 bits (80), Expect = 0.090, Method: Compositional matrix adjust.
Identities = 18/50 (36%), Positives = 27/50 (54%)
Frame = -2
Query: 588 YRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFK 637
Y APE+L + AVD WS+G + ++LT P F + I+K+ K
Sbjct: 760 YMAPEILTRTG-HGKAVDWWSLGALMYDMLTGSPPFTAENRKKTIDKILK 614
>36481
Length = 806
Score = 33.1 bits (74), Expect = 0.42, Method: Compositional matrix adjust.
Identities = 37/149 (24%), Positives = 66/149 (44%), Gaps = 6/149 (4%)
Frame = +2
Query: 413 ALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLK-MEKEKEGFPITSLREI 471
++G S + + EGT+G V + KD + +ALK +K ++K +E + EI
Sbjct: 338 TMRGTSSTNDMKLCPHWGEGTFGKVVQCKDLLKGDDIALKIIKNVDKYREAAKL----EI 505
Query: 472 NTILKAQ----HPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGE-VKT 526
N + K + H + V+ + + I + + + ++ P E V+
Sbjct: 506 NVLEKLREKDPHAKHMCVQMLDWFDYHGHVCISFHMLGLSVFDFLKDNSYGAYPIEQVRH 685
Query: 527 LMIQLLRGVKHLHDNWILHRDLKTSNLLL 555
+ QL V LH+N + H DLK N+L
Sbjct: 686 ISYQLCYAVNFLHENQLTHTDLKPENILF 772
>15931
Length = 447
Score = 30.4 bits (67), Expect = 2.6, Method: Compositional matrix adjust.
Identities = 13/31 (41%), Positives = 19/31 (61%)
Frame = +1
Query: 680 QGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 710
Q FDLM+K L+Y R S ++H +FR+
Sbjct: 70 QLFDLMDKMLSYEVSTRYSLRQAMRHPFFRK 162
>00145
Length = 2325
Score = 30.4 bits (67), Expect = 3.0, Method: Composition-based stats.
Identities = 18/46 (39%), Positives = 24/46 (52%), Gaps = 1/46 (2%)
Frame = -1
Query: 693 PGRRISAEDGLKHEYFRETP-LPIDPSMFPTWPAKSEQQRVKRGTS 737
P RIS DG + RE+P LP D + P P + Q+ V R T+
Sbjct: 2313 PQHRISQSDGESVDVQRESPLLPRDGAAVPQRPGPAAQEGVSRQTA 2176
>20152
Length = 445
Score = 30.0 bits (66), Expect = 3.9, Method: Compositional matrix adjust.
Identities = 14/33 (42%), Positives = 20/33 (60%)
Frame = +1
Query: 591 PELLLGAKEYSTAVDMWSVGCIFGELLTQKPLF 623
PE+LLG + AVD+WS+G I L+ + F
Sbjct: 1 PEILLGDSYDAPAVDVWSLGVILYMLVVGEAPF 99
>38560
Length = 479
Score = 29.3 bits (64), Expect = 6.5, Method: Composition-based stats.
Identities = 12/30 (40%), Positives = 18/30 (60%)
Frame = -3
Query: 588 YRAPELLLGAKEYSTAVDMWSVGCIFGELL 617
Y APEL+ G + + D+WS+G + LL
Sbjct: 387 YAAPELISGLEYLGSEADIWSMGVLLYALL 298
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000348529 | hsapiens_gene_ensembl | PITSLRE
serine/threonine-protein kinase CDC2L2 (EC 2.7.11.22)
(Galactosyltransferase-associated protein kinase p58/GTA) (Cell
division cycle 2-like protein kinase 2) (CDK11).
[Source:Uniprot/SWISSPROT;Acc:Q9UQ88]
(746 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
29581 292 5e-84
01060 229 3e-60
01756 223 3e-58
14126 219 2e-57
04591 196 4e-50
32000 170 2e-42
01707 162 4e-40
04138 151 1e-36
01966 118 3e-28
23319 103 3e-22
00300 95 1e-19
03294 87 2e-17
18921 86 7e-17
06405 83 4e-16
13592 82 6e-16
12721 82 8e-16
01718 80 4e-15
09606 77 2e-14
03508 77 4e-14
20559 66 1e-13
12453 74 2e-13
14420 73 3e-13
15910 71 2e-12
26560 68 1e-11
19761 65 8e-11
18484 65 8e-11
21578 64 2e-10
27546 63 4e-10
14116 62 9e-10
03240 62 1e-09
30755 61 1e-09
13212 61 2e-09
28638 61 2e-09
13066 60 3e-09
26909 60 3e-09
19094 59 8e-09
21808 58 1e-08
11185 57 4e-08
19301 56 6e-08
27405 56 6e-08
07940 56 7e-08
18287 55 8e-08
26711 55 8e-08
24241 55 9e-08
28157 55 1e-07
31489 55 1e-07
12672 54 3e-07
17253 53 4e-07
04852 53 5e-07
00715 52 1e-06
18401 52 1e-06
21079 51 2e-06
16003 51 2e-06
00392 50 3e-06
12786 50 4e-06
17300 50 4e-06
31885 47 2e-05
11780 46 5e-05
05084 45 1e-04
20640 44 2e-04
07836 44 3e-04
17975 44 3e-04
21433 42 0.001
07291 42 0.001
15549 40 0.002
02638 39 0.005
14477 39 0.006
37602 39 0.008
16708 39 0.008
26009 32 0.008
13078 38 0.012
18481 38 0.013
00486 35 0.079
36481 33 0.38
00145 31 1.9
15931 30 2.5
20152 30 3.6
38560 29 6.2
>29581
Length = 1278
Score = 292 bits (747), Expect(2) = 5e-84, Method: Compositional matrix adjust.
Identities = 133/261 (50%), Positives = 183/261 (70%)
Frame = -2
Query: 440 ILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLR 499
+L +H NIV ++E+VVG ++D +++VM Y E DL SL++ M PF +VK +++QLL+
Sbjct: 1193 LLNLRHQNIVQLQEVVVGKSLDSLFLVMEYCEQDLASLLDNMPAPFSESQVKCIVLQLLK 1014
Query: 500 GVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPEL 559
G+++LH+ +I+HRDLK SNLL++ G +K+ DFGLAR YG P K TP VVT WYRAPEL
Sbjct: 1013 GLRYLHEAFIIHRDLKVSNLLMTDKGCVKIADFGLARNYGKPQKPMTPKVVTLWYRAPEL 834
Query: 560 LLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSEL 619
L G+K +STA+DMWS GCI GELL KPL PG S++ QI + + LGTP++ IWPG+S+L
Sbjct: 833 LFGSKTHSTAIDMWSAGCILGELLGHKPLMPGRSDLQQIELIMELLGTPNDTIWPGFSQL 654
Query: 620 PVVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPL 679
P ++ T + PYNNLR F LS+ G L+N Y P +R +AED L+H YF+E P
Sbjct: 653 PAFEQFTLKKQPYNNLRHTF-PWLSESGIRLLNGLFMYHPQKRATAEDCLEHSYFKEQPY 477
Query: 680 PIDPSMFPTWPAKSEQQRVKR 700
P DP P++P Q R+KR
Sbjct: 476 PCDPEFMPSFP----QHRLKR 426
Score = 38.9 bits (89), Expect(2) = 5e-84, Method: Composition-based stats.
Identities = 17/35 (48%), Positives = 25/35 (71%)
Frame = -1
Query: 412 DEIVALKRLKMEKEKEGFPITSLREINTILKAQHP 446
+EIVALK+++M E+ G PI+ LREIN ++ P
Sbjct: 1278 NEIVALKKMRMTGERYGIPISGLREINIFAQSATP 1174
>01060
Length = 1800
Score = 229 bits (584), Expect = 3e-60, Method: Compositional matrix adjust.
Identities = 122/338 (36%), Positives = 204/338 (60%), Gaps = 2/338 (0%)
Frame = +1
Query: 364 LLPIELKQELPKYLPALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKME 423
LL + +K+ + + AL + +FQ +I EGTYGVVY+ + + T +A+K++++
Sbjct: 22 LLKLNIKRLMMDFETALS---DLTDFQ---KIGEGTYGVVYKCRHRATGRKLAMKKIRLR 183
Query: 424 KEKEGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQ 483
++G P +++REI + + +H NIV + ++++ +++++V ++ DLK ++ +
Sbjct: 184 GSEDGVPSSAIREIAMLRELRHTNIVCLEDVIMED--ERLFLVFEFLSMDLKMYIDKFPE 357
Query: 484 PFLPGE--VKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSP 541
+ VK+ + Q++ G+ H I+HRDLK NLL++H G +K+ DFG+AR + P
Sbjct: 358 GVVLDRRLVKSYVFQIVTGIXFCHQRRIVHRDLKPQNLLINHTGAIKIADFGMARTFALP 537
Query: 542 LKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKV 601
++AYT VVT WYRAPE+L+GA +YST VD+WS+G IF ++L + P+F G+SEIDQ+ K+
Sbjct: 538 VRAYTHEVVTLWYRAPEILMGASKYSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKI 717
Query: 602 FKELGTPSEKIWPGYSELPVVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGR 661
F+ +GTP+E+ WP + +LP M F L + L S G DL+ + L P +
Sbjct: 718 FRIIGTPTEQTWPEFHKLPAFNGM-FPLWKEGKLSETLTDLDS-LGLDLIERTLKCDPAQ 891
Query: 662 RISAEDGLKHEYFRETPLPIDPSMFPTWPAKSEQQRVK 699
RIS + L+H YF + P P+ P S R+K
Sbjct: 892 RISCKKMLQHAYFLNVDTSVKPVDVPS-PEHS*STRLK 1002
>01756
Length = 1858
Score = 223 bits (567), Expect = 3e-58, Method: Compositional matrix adjust.
Identities = 117/309 (37%), Positives = 187/309 (60%), Gaps = 10/309 (3%)
Frame = -3
Query: 383 CRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILK 442
C +++ L +I +GT+G V++A+ KKT ++VA+K++ M+ EKEGFPIT+LREI +
Sbjct: 1754 CDEDAKYEKLAKIGQGTFGEVFKARCKKTKQVVAMKKVLMDNEKEGFPITALREIKILQL 1575
Query: 443 AQHPNIVTVREIV----VGSNMDK--IYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQ 496
H N+V + EI +N K Y+V + EHDL L+ M F E+K +M Q
Sbjct: 1574 LNHENVVDLIEICSTKATSANRYKSMFYLVFEFCEHDLAGLLSNMSVVFNLPEIKEVMKQ 1395
Query: 497 LLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKA---YTPVVVTQW 553
L+ G+ ++H N ILHRD+K +N+L++ G+LK+ DFGLAR + L+ YT VVT W
Sbjct: 1394 LMNGLYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLW 1215
Query: 554 YRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIW 613
YR PELLLG + YSTA+D W GCI E+ T+ P+ G +E +Q+ + + G+ + ++W
Sbjct: 1214 YRPPELLLGDRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQNQLTLITQLCGSITPEVW 1035
Query: 614 PGYSELPVVKKMTFSEHPYNNLRKRFGALLSDQ-GFDLMNKFLTYFPGRRISAEDGLKHE 672
PG L + + + +++R + D DL++K L PG+R+++++ L H+
Sbjct: 1034 PGVERLELYNSLDLPQGNKRKVKERLRYYIKDAYALDLLDKLLALDPGKRVNSDEALSHD 855
Query: 673 YFRETPLPI 681
+F P P+
Sbjct: 854 FFWMDPEPL 828
>14126
Length = 1265
Score = 219 bits (559), Expect = 2e-57, Method: Compositional matrix adjust.
Identities = 125/299 (41%), Positives = 182/299 (60%), Gaps = 9/299 (3%)
Frame = +3
Query: 387 EEFQCLNRIEEGTYGVVYRAKD-KKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQ- 444
++++ + I G YG VY+A+D + E VA+KR+++ +EG P+ ++REI+ + + +
Sbjct: 189 QKYEEVAVIGNGAYGTVYKARDLRNQGEFVAMKRIRLNNTEEGMPMMAIREISMLKQLEQ 368
Query: 445 --HPNIVTVREIVVGSNMDK---IYIVMNYVEHDLKSLMETMKQPFL-PGEVKTLMIQLL 498
HPN+V + ++ + D+ + +V Y+EHDL + + P L P +K LM+QLL
Sbjct: 369 YEHPNVVRLLDVSHNTITDREIRLNLVFEYIEHDLATYLAKCPSPGLGPDRIKDLMLQLL 548
Query: 499 RGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPE 558
GV LH N I+HRDLK NLL+S G LK+ DFGLAR Y + A T VVVT WYR+PE
Sbjct: 549 NGVDFLHSNRIVHRDLKPQNLLISKDGRLKLADFGLARIYSFHM-ALTTVVVTLWYRSPE 725
Query: 559 LLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWP-GYS 617
+L+ A EY T+VD+WS GCIF EL T++ LF G+SE DQ+ K+F+ +G P WP G S
Sbjct: 726 VLMQA-EYGTSVDIWSCGCIFAELFTRRALFKGSSEFDQLKKIFEVIGLPPAGDWPEGVS 902
Query: 618 ELPVVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 676
V + +F P L+ + Q DLM K L + GRRIS+ + L H Y R+
Sbjct: 903 ----VHRNSFRPTPPVPLQTLVPE-MDPQAKDLMEKMLVFKSGRRISSRESLLHPYLRD 1064
>04591
Length = 1117
Score = 196 bits (497), Expect = 4e-50, Method: Compositional matrix adjust.
Identities = 102/267 (38%), Positives = 161/267 (60%), Gaps = 7/267 (2%)
Frame = -2
Query: 426 KEGFPITSLREINTILKAQHPNIVTVREIV------VGSNMDKIYIVMNYVEHDLKSLME 479
KEGFPIT+LREI + + +H N+V ++EI Y++ Y ++DL L+
Sbjct: 1101 KEGFPITALREIKILQQLEHENVVQLQEICHTQAGPYNRYKSTFYLIFEYCDYDLAGLLN 922
Query: 480 TMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYG 539
++ F + K LM QLL G+ ++H ILHRD+K +N+LL+ G+LK+ DFGL+R +
Sbjct: 921 NLRVKFSLADKKNLMSQLLNGLFYIHTKQILHRDIKAANILLTRDGVLKLADFGLSRPWV 742
Query: 540 SPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQIN 599
K T VVT WYR PELLLG +EY +DMW VGCI E+ ++KPL G SE Q++
Sbjct: 741 KS-KRLTNRVVTLWYRPPELLLGEREYGPEIDMWGVGCIMAEMWSRKPLMQGRSEQHQLS 565
Query: 600 KVFKELGTPSEKIWPGYSELPVVKKMTFSEHPYNNLRKRFGALLSD-QGFDLMNKFLTYF 658
+ G+ + ++WPG ++L + K+ + +++R LL + +G +L++ FL
Sbjct: 564 LITDLCGSLNAEVWPGVTKLELYGKLDLPQGKPRKVKERMLDLLKNKEGAELIDIFLRLD 385
Query: 659 PGRRISAEDGLKHEYFRETPLPIDPSM 685
PG+R++ ++ L H++F PLP PS+
Sbjct: 384 PGQRMNCDNALSHDFFWVDPLP-SPSL 307
>32000
Length = 644
Score = 170 bits (431), Expect = 2e-42, Method: Compositional matrix adjust.
Identities = 79/150 (52%), Positives = 106/150 (70%)
Frame = -1
Query: 527 LKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQK 586
+K+ DFGLAR +G P++ YT V+T WYRAPE+LLG + YS VD+WS+GCIF E++T++
Sbjct: 572 MKIADFGLARVFGLPVRTYTHEVITLWYRAPEILLGCRFYSVPVDIWSLGCIFVEMMTRR 393
Query: 587 PLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKMTFSEHPYNNLRKRFGALLSDQ 646
LFPG+SEIDQ+ ++F+ LGTP EK+WPG S+LP K TF + P NL LS
Sbjct: 392 ALFPGDSEIDQLYRIFRTLGTPDEKVWPGVSKLPDYKP-TFPKWPLKNLETVVS--LSKV 222
Query: 647 GFDLMNKFLTYFPGRRISAEDGLKHEYFRE 676
G DL+ + LTY P RRISA ++H YF +
Sbjct: 221 GLDLLKRMLTYNPNRRISARSAMRHPYFND 132
>01707
Length = 757
Score = 162 bits (411), Expect = 4e-40, Method: Compositional matrix adjust.
Identities = 81/221 (36%), Positives = 138/221 (62%)
Frame = +1
Query: 386 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 445
+E+++ + +I EG+YGVV++ ++K+T ++VA+K+ ++ ++REI + + +H
Sbjct: 61 MEKYEKIGKIGEGSYGVVFKCRNKETSQLVAIKKFVESEDDPLIKKIAMREIRMLKQLKH 240
Query: 446 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLH 505
PN+V R I V ++++V +YV+H L + ++ + VK ++ Q L V H
Sbjct: 241 PNLV--RLIEVFRRKKRLHLVFDYVDHTLLNELDRYPRGLPEPMVKRIIYQTLLAVNFCH 414
Query: 506 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKE 565
+HRD+K N+L++ G +K+ DFG AR P YT V T+WYRAPELL+G +
Sbjct: 415 QYNTIHRDVKPENILITRQGQVKLCDFGFARILTGPGDEYTDYVATRWYRAPELLVGDTQ 594
Query: 566 YSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELG 606
Y VD+W++GC+F ELLT + L+PG S++DQ++ + K LG
Sbjct: 595 YGPPVDVWAIGCVFAELLTGQALWPGRSDVDQLHLIRKTLG 717
>04138
Length = 800
Score = 151 bits (381), Expect = 1e-36, Method: Compositional matrix adjust.
Identities = 72/178 (40%), Positives = 111/178 (62%), Gaps = 6/178 (3%)
Frame = +1
Query: 503 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKA---YTPVVVTQWYRAPEL 559
++H N ILHRD+K +N+L++ G+LK+ DFGLAR + L+ YT VVT WYR PEL
Sbjct: 58 YIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRPPEL 237
Query: 560 LLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSEL 619
LLG + YSTA+D W GCI E+ T+ P+ G +E +Q+ + + G+ + ++WPG ++L
Sbjct: 238 LLGDRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQNQLTLITQLCGSITPEVWPGVTQL 417
Query: 620 PVVKKM--TFSEHPYNNLRKRFGALLSD-QGFDLMNKFLTYFPGRRISAEDGLKHEYF 674
+ ++ + N +R RF +L D G DL + L P +RISA++ L H++F
Sbjct: 418 SMYHQIKGALAAGRKNIIRDRFARILKDPYGLDLFERLLKMDPSQRISADEALNHDFF 591
>01966
Length = 1735
Score = 118 bits (296), Expect(2) = 3e-28, Method: Compositional matrix adjust.
Identities = 55/175 (31%), Positives = 107/175 (61%), Gaps = 2/175 (1%)
Frame = -1
Query: 406 AKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYI 465
+ + T +A+K++++ ++G P +++REI + + +H NIV + ++++ +++++
Sbjct: 1654 CRHRATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTNIVCLEDVIMED--ERLFL 1481
Query: 466 VMNYVEHDLKSLMETMKQPFLPGE--VKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSH 523
V ++ DLK ++ + + VK+ + Q++ G+ H I+HRDLK NLL++H
Sbjct: 1480 VFEFLSMDLKMYIDKFPEGVVLDRRLVKSYVFQIVTGINFCHQRRIVHRDLKPQNLLINH 1301
Query: 524 AGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCI 578
G +K+ DFG+AR + P++AYT VVT WYRAPE+L+G + + W+ G +
Sbjct: 1300 TGAIKIADFGMARTFALPVRAYTHEVVTLWYRAPEILMGPQ---STPPXWTCGAL 1145
Score = 25.4 bits (54), Expect(2) = 3e-28, Method: Composition-based stats.
Identities = 10/13 (76%), Positives = 12/13 (92%)
Frame = -2
Query: 392 LNRIEEGTYGVVY 404
L++I EGTYGVVY
Sbjct: 1695 LSKIGEGTYGVVY 1657
Score = 97.8 bits (242), Expect = 1e-20, Method: Compositional matrix adjust.
Identities = 54/138 (39%), Positives = 80/138 (57%)
Frame = -3
Query: 562 GAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPV 621
GA +YST VD+WS+G IF ++L + P+F G+SEIDQ+ K+F+ +GTP+E+ WP + +LP
Sbjct: 1187 GASKYSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKLPA 1008
Query: 622 VKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPI 681
M F L + L S G DL+ + L P +RIS + L+H YF +
Sbjct: 1007 FNGM-FPLWKEGKLSETLTDLDS-LGLDLIERTLKCDPAQRISCKKMLQHAYFLNVDTSV 834
Query: 682 DPSMFPTWPAKSEQQRVK 699
P P+ P +S R+K
Sbjct: 833 KPVDVPS-PEQS*STRLK 783
>23319
Length = 2235
Score = 103 bits (256), Expect = 3e-22, Method: Compositional matrix adjust.
Identities = 50/117 (42%), Positives = 72/117 (61%), Gaps = 1/117 (0%)
Frame = +3
Query: 563 AKEYSTAVDMWSVGCIFGELLTQ-KPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPV 621
AK YST++DMWS GCIF EL +PLFPGN + DQ+ ++FK LGTP+E WPG ++LP
Sbjct: 18 AKMYSTSIDMWSAGCIFAELANAGRPLFPGNDDDDQLKRIFKLLGTPTEDQWPGMTQLPN 197
Query: 622 VKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETP 678
+ F + ++ L+ +G DL+ L P R+SA++ L+H YF + P
Sbjct: 198 YR--MFPMYHVTTTWQQVVPKLNSKGRDLLQCLLVCCPSDRMSADEALQHPYFADLP 362
>00300
Length = 2318
Score = 95.1 bits (235), Expect = 1e-19, Method: Compositional matrix adjust.
Identities = 66/207 (31%), Positives = 108/207 (52%), Gaps = 13/207 (6%)
Frame = -1
Query: 393 NRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKA----QHPNI 448
N+I EG +G VY A + T E++ALK +K + + LRE+ +K QH N+
Sbjct: 1640 NKIGEGQFGKVYTAVNMSTGELMALKEMKFQPND----LQQLREMCDEIKIFEGIQHENL 1473
Query: 449 VTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNW 508
V + V + D++ + M Y D ++ E K ++ +++ V HLH+N
Sbjct: 1472 VKYYGVEV--HKDEMLMFMEYC--DTGTIEEAAKMGLPEYLIRRYTREIVLAVNHLHENS 1305
Query: 509 ILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTP-------VVVTQWYRAPELLL 561
I+HRD+K +N+ L+ G +K+GDFG + + LK++T +V T Y APE+
Sbjct: 1304 IVHRDIKGANIFLTSNGHVKLGDFGCSVK----LKSHTTMPGEFHNLVGTTAYMAPEVFT 1137
Query: 562 GAKE--YSTAVDMWSVGCIFGELLTQK 586
+ Y A D+WS+GC+ E+ T K
Sbjct: 1136 QNDQGGYGRAADIWSLGCVVIEMATGK 1056
>03294
Length = 1684
Score = 87.4 bits (215), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 49/130 (37%), Positives = 73/130 (56%)
Frame = -1
Query: 570 VDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKMTFSE 629
VD+WS+G IF ++L + P+F G+SEIDQ+ K+F+ +GTP+E+ WP + +LP M F
Sbjct: 1672 VDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKLPAFNGM-FPL 1496
Query: 630 HPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSMFPTW 689
L + L S G DL+ + L P +RIS + L+H YF + P P+
Sbjct: 1495 WKEGKLSETLTDLDS-LGLDLIERTLKCDPAQRISCKKMLQHAYFLNVDTSVKPVDVPS- 1322
Query: 690 PAKSEQQRVK 699
P S R+K
Sbjct: 1321 PEHS*STRLK 1292
>18921
Length = 697
Score = 85.5 bits (210), Expect = 7e-17, Method: Compositional matrix adjust.
Identities = 57/205 (27%), Positives = 109/205 (53%), Gaps = 6/205 (2%)
Frame = +2
Query: 389 FQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNI 448
F L ++ EG+YG V+++ K+T +++A+K++ ++ + + ++EI+ + + I
Sbjct: 35 FDILGKLGEGSYGSVFKSLHKETGQVLAIKQVPVDTDLQEI----IKEISIMQQCDSKYI 202
Query: 449 VTVREIVVGS---NMDKIYIVMNYV-EHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHL 504
V GS N D ++IVM Y + +M + + E+ T++ L+G+ +L
Sbjct: 203 VKYY----GSYFKNTD-LWIVMEYCGAGSVSDIMRLRNKTLVEREIATILYYTLKGLXYL 367
Query: 505 HDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELL--LG 562
H +HRD+K N+LL++ G K+ DFG+A + + V+ T ++ APE++ +G
Sbjct: 368 HSRRKIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTPYWMAPEVIQEIG 547
Query: 563 AKEYSTAVDMWSVGCIFGELLTQKP 587
Y D+WS+G E+ KP
Sbjct: 548 ---YDCVADIWSLGITALEMAEGKP 613
>06405
Length = 1965
Score = 83.2 bits (204), Expect = 4e-16, Method: Compositional matrix adjust.
Identities = 63/205 (30%), Positives = 102/205 (49%), Gaps = 8/205 (3%)
Frame = +1
Query: 388 EFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILK-AQHP 446
E +R+ G YG VY A K+ ++IVA+K LK ++ + E I+K +HP
Sbjct: 262 EIAMKHRLGGGQYGDVYEAMWKRYNKIVAVKTLK----EDTMALNDFLEEAAIMKEMKHP 429
Query: 447 NIVTVREIVVGSNMDKIYIVMNYVEHD--LKSLMETMKQPFLPGEVKTLMIQLLRGVKHL 504
N+V + + V + YIV ++ H L L + ++ P + + Q+ G+ +L
Sbjct: 430 NLVQL--LGVCTREPPFYIVTEFMPHGNLLDYLRSSTREENGPTALMYMATQIASGMAYL 603
Query: 505 HDNWILHRDLKTSNLLLSHAGILKVGDFGLAR-----EYGSPLKAYTPVVVTQWYRAPEL 559
+HRDL N L++ + ++KV DFGLAR Y + + A P+ +W APE
Sbjct: 604 ETKNFIHRDLAARNCLVADSNMVKVADFGLARLMKDDTYTAHIGAKFPI---KW-TAPE- 768
Query: 560 LLGAKEYSTAVDMWSVGCIFGELLT 584
L +ST D+W+ G + EL T
Sbjct: 769 GLAFNRFSTRSDIWAFGVLLWELAT 843
>13592
Length = 980
Score = 82.4 bits (202), Expect = 6e-16, Method: Compositional matrix adjust.
Identities = 80/295 (27%), Positives = 138/295 (46%), Gaps = 13/295 (4%)
Frame = +2
Query: 394 RIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVRE 453
+I +G +G VY A + T E++A+K + ++ + E+ + +H N+V
Sbjct: 5 KIGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETRALKNVAEELKILEGIKHKNLVRYYG 184
Query: 454 IVVGSNMDKIYIVMNYV-EHDLKSLMETMKQPFLPGEV-KTLMIQLLRGVKHLHDNWILH 511
I V + +++ I M E L+SL+E LP + + QLL GV LH + I+H
Sbjct: 185 IEV--HREELLIFMELCSEGTLESLVELTGG--LPEALSRRFTAQLLSGVAELHKHGIVH 352
Query: 512 RDLKTSNL-LLSHAGILKVGDFGLAREYGSPLKAYTPV-------VVTQWYRAPELL--L 561
RD+KT+N+ L+ + LK+GDFG A + ++A+T V V TQ Y APE+
Sbjct: 353 RDIKTANIFLVDGSNSLKLGDFGSAVK----IQAHTTVPGELQGYVGTQAYMAPEVFTKT 520
Query: 562 GAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGY-SELP 620
+ + D+WSVGC+ E+ + K + W + S
Sbjct: 521 NSDGHGRLADIWSVGCVVVEMASGK------------------------RPWAQFDSNFQ 628
Query: 621 VVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFR 675
++ K+ E P + LS +G D ++ L + P +R+SA + L+ + +
Sbjct: 629 IMFKVGMGEKP------QAPESLSQEGHDFIDHCLQHDPKQRLSAIELLEQNFCK 775
>12721
Length = 821
Score = 82.0 bits (201), Expect = 8e-16, Method: Compositional matrix adjust.
Identities = 53/196 (27%), Positives = 106/196 (54%)
Frame = +1
Query: 394 RIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVRE 453
+I EG+ G+V A + ++ A+K++ + K++ + E+ + HPNIV +
Sbjct: 109 KIGEGSTGIVCIATSRDGRQM-AVKKMDLRKQQRRELL--FNEVVVMRDYHHPNIVEMYN 279
Query: 454 IVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRD 513
+ + D++++VM ++E + + T + ++ T+ L+ + LH N ++HRD
Sbjct: 280 SYLVN--DELWVVMEFMEGGALTDIVTNNR-MDEVQIATVCRACLKALAFLHANGVIHRD 450
Query: 514 LKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMW 573
+K+ ++LLSH G +K+ DFG + L+ +V T ++ APE ++ Y VD+W
Sbjct: 451 IKSDSILLSHDGKVKLXDFGFCAQVTQDLQKRKSLVGTPYWMAPE-VISRLPYGPEVDIW 627
Query: 574 SVGCIFGELLTQKPLF 589
S+G + E++ +P F
Sbjct: 628 SLGIMVMEMIDAEPPF 675
>01718
Length = 959
Score = 79.7 bits (195), Expect = 4e-15, Method: Compositional matrix adjust.
Identities = 60/218 (27%), Positives = 107/218 (49%), Gaps = 6/218 (2%)
Frame = +3
Query: 379 ALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREIN 438
A+ +++F C +I G + V++ + T +++ALK M + LRE+
Sbjct: 126 AVSALTRLDDFIC-EKIGAGFFSEVFKVTHRITGQVMALKMNTMTSNRHNM----LREVQ 290
Query: 439 TILKAQHPNIVTVREIVVGSNMDKIYIVMNYV-EHDLKSLMETMKQPFLPGEVKTLMIQL 497
+ + QH NI+ + V +++ + Y+ +L+ L+E + + L + L
Sbjct: 291 LLNRLQHANILRFMGVCVHEG--QLHALTEYIPSGNLEQLLEKKDEELPWTQRIQLTLGL 464
Query: 498 LRGVKHLHDNWILHRDLKTSNLLL----SHAGILKVGDFGLAREYGSPL-KAYTPVVVTQ 552
RG+ +LH +HRDL + N+L+ +H + DFGLA + PL K P V +
Sbjct: 465 ARGLDYLHSTRFIHRDLTSKNILIRREDNHGYHAVIADFGLATKIPDPLDKEKLPTVGSP 644
Query: 553 WYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFP 590
++ APE+L G Y+ D++SVG I E+ + P P
Sbjct: 645 YWMAPEVLNG-HFYNERADLFSVGIIMCEITARIPADP 755
>09606
Length = 1300
Score = 77.4 bits (189), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 82/314 (26%), Positives = 134/314 (42%), Gaps = 24/314 (7%)
Frame = -3
Query: 386 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 445
+E F + +G + ++Y+ + K T VA+ + EK K ++R + I H
Sbjct: 1118 MENFVLYEELGKGEHSIIYKGRRKGTINFVAIHCI--EKCKRPEVTNTVRMTHDI---SH 954
Query: 446 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPF-LP-GEVKTLMIQLLRGVKH 503
PN+V E SN +++V+ SL + + Q LP ++ I L+ G+ +
Sbjct: 953 PNVVQFHEWYETSN--HLWLVVELCTGG--SLADILAQDHHLPETSIRDFGIHLVTGLHY 786
Query: 504 LHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAY------------------ 545
+H IL DL+ S +LL +G+LK DFGL++ G L+
Sbjct: 785 IHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQWNIQSAEE 606
Query: 546 ----TPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKV 601
P + Y APE+ GA E S D+W++GC+F E+ + P F G + +KV
Sbjct: 605 MMKQVPTSGSPTYMAPEVFQGA-EPSIMSDLWALGCVFYEMFSGHPPFLGETYDITKDKV 429
Query: 602 FKELGTPSEKIWPGYSELPVVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGR 661
K +P LP VK S P S + +L+ L R
Sbjct: 428 LN-------KEFP----LPKVKGSRLSAKP------------SPEFLNLLESLLQKDSTR 318
Query: 662 RISAEDGLKHEYFR 675
R+S +KH +++
Sbjct: 317 RLSWASLVKHAFWQ 276
>03508
Length = 1463
Score = 76.6 bits (187), Expect = 4e-14, Method: Compositional matrix adjust.
Identities = 39/122 (31%), Positives = 72/122 (59%), Gaps = 2/122 (1%)
Frame = +1
Query: 471 EHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGI-LKV 529
EH + + + Q F +++ + +L++ + H I+HRD+K N+++ H L++
Sbjct: 820 EHVNNTDFKQLYQTFTDYDIRFYLYELMKALDFCHSMGIMHRDVKPHNVMIDHENKKLRL 999
Query: 530 GDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQK-PL 588
D+GLA E+ P Y V +++++ PELLL + Y ++DMWS+GC+F ++ +K PL
Sbjct: 1000IDWGLA-EFYHPGMEYNVRVASRYFKGPELLLDYQMYDYSLDMWSLGCMFASMIFRKEPL 1176
Query: 589 FP 590
P
Sbjct: 1177LP 1182
Score = 35.0 bits (79), Expect = 0.099, Method: Compositional matrix adjust.
Identities = 27/114 (23%), Positives = 51/114 (44%), Gaps = 12/114 (10%)
Frame = +2
Query: 573 WSVG----CIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKMTFS 628
W+ G C+ + P F G+ DQ+ ++ K LGT + ++ + + F+
Sbjct: 1118 WTCGVWAACLPA*SSGKSPFFHGHDNYDQLVRIAKVLGT--DDLYGYIEKYQIDLDPRFN 1291
Query: 629 EHPYNNLRKRF--------GALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYF 674
+ + RKR+ L+S + D ++K L Y R++A + + H YF
Sbjct: 1292 DILGRHSRKRWERFVHSENQHLISPEALDFLDKLLRYDHNERLTAREAMDHPYF 1453
>20559
Length = 430
Score = 65.9 bits (159), Expect(2) = 1e-13, Method: Compositional matrix adjust.
Identities = 31/82 (37%), Positives = 58/82 (70%)
Frame = -2
Query: 374 PKYLPALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITS 433
P +L + +++++ L +I EGTYG V++AK+++T EIVALKR++++ + EG P ++
Sbjct: 414 PTHLHSF*LKHKMQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSA 235
Query: 434 LREINTILKAQHPNIVTVREIV 455
LREI + + +H NIV + +++
Sbjct: 234 LREICLLKELKHRNIVRLHDVL 169
Score = 29.3 bits (64), Expect(2) = 1e-13, Method: Composition-based stats.
Identities = 14/36 (38%), Positives = 19/36 (52%)
Frame = -3
Query: 469 YVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHL 504
Y + DLK +T P VK+ + QLLRG+ L
Sbjct: 134 YCDQDLKKYFDTCNGEIDPDTVKSFLHQLLRGLGFL 27
>12453
Length = 680
Score = 73.9 bits (180), Expect = 2e-13, Method: Composition-based stats.
Identities = 41/100 (41%), Positives = 55/100 (55%)
Frame = +3
Query: 575 VGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKMTFSEHPYNN 634
VGCIF E+ +PLFPG++ D+++ +FK LGTP+E P S P + +
Sbjct: 6 VGCIFYEMACGRPLFPGSTVEDELHLIFKTLGTPTEDSLPSISRNPDFLALNLPHYQGEA 185
Query: 635 LRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYF 674
L L SD G DL+ KFL Y R+SA D LKH +F
Sbjct: 186 LITIAPRLDSD-GLDLLAKFLKYNAKIRVSAADSLKHSFF 302
>14420
Length = 528
Score = 73.2 bits (178), Expect = 3e-13, Method: Compositional matrix adjust.
Identities = 44/156 (28%), Positives = 90/156 (57%), Gaps = 2/156 (1%)
Frame = +2
Query: 434 LREINTILKAQHPNIVT-VREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLP-GEVK 491
+ EI + + Q+PNIV + +VG +++++VM ++ SL + + + + G++
Sbjct: 44 INEILVMRENQNPNIVNYLDSYLVG---EELWVVMEFLAGG--SLTDVVTETCMDEGQIA 208
Query: 492 TLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVT 551
+ + L+ ++ LH+N ++HRD+K+ N+LL G +K+ DFG + + +V T
Sbjct: 209 AVCRECLQALEFLHENQVIHRDIKSDNILLGMDGSVKLTDFGFCAQLSPEQSKRSTMVGT 388
Query: 552 QWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKP 587
++ APE ++ K+Y VD+WS+G + E++ +P
Sbjct: 389 PYWMAPE-VVTRKQYGPTVDIWSLGVMCIEMIEGEP 493
>15910
Length = 1361
Score = 70.9 bits (172), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 49/125 (39%), Positives = 67/125 (53%), Gaps = 3/125 (2%)
Frame = +2
Query: 497 LLRGVKHLHDNWILHRDLKTSNLL---LSHAGILKVGDFGLAREYGSPLKAYTPVVVTQW 553
+L GV+++H N ++HRDLK NLL ++ LK+ DFGL+R P + V T
Sbjct: 491 ILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLADFGLSR-IIEPEVQMSTVCGTPG 667
Query: 554 YRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIW 613
Y APE+L G K Y+ +VDMWSVG I LL F +E + K+ K E+ W
Sbjct: 668 YCAPEVLKGDK-YTPSVDMWSVGVIAYILLCGYEPFFAENEFEMYRKIIKGEYKFDEEYW 844
Query: 614 PGYSE 618
SE
Sbjct: 845 SEISE 859
>26560
Length = 398
Score = 68.2 bits (165), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 37/119 (31%), Positives = 66/119 (55%), Gaps = 4/119 (3%)
Frame = -1
Query: 485 FLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKA 544
F EV+ +++ G++H+H ++++RDLK +N+LL G +++ D GLA ++ K
Sbjct: 365 FTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGLACDFSK--KR 192
Query: 545 YTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLF----PGNSEIDQIN 599
V T Y APE+L+ + Y ++ D +S GC+ +LL F G + ID++
Sbjct: 191 PHASVGTHGYMAPEVLMKGQSYDSSADWFSFGCMLYKLLKGHSPFRQHNQGQARIDRMT 15
>19761
Length = 473
Score = 65.5 bits (158), Expect = 8e-11, Method: Compositional matrix adjust.
Identities = 36/104 (34%), Positives = 60/104 (57%)
Frame = -3
Query: 503 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLG 562
H H ILHRDLK N+ ++ G +++GD GLAR+ P T V T Y +PE +L
Sbjct: 372 HTHTPVILHRDLKPQNIYVTEKGDVRLGDLGLARKLTGPADFATSQVGTIMYLSPE-ILS 196
Query: 563 AKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELG 606
+ Y++ D+WS+GC+F ++ +K G+ E+ + + + +G
Sbjct: 195 QQPYNSKSDIWSLGCVFYDITGKK----GSDEMGVMFLLVQVMG 76
>18484
Length = 635
Score = 65.5 bits (158), Expect = 8e-11, Method: Compositional matrix adjust.
Identities = 35/99 (35%), Positives = 55/99 (55%)
Frame = +1
Query: 496 QLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYR 555
++ G+ LHD I++RDLK N++L G +K+ DFG+ +E + T Y
Sbjct: 67 EIAVGLFFLHDQGIIYRDLKLDNVMLDSEGHIKIADFGMCKEGMTGDATTRTFCGTPDYI 246
Query: 556 APELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSE 594
APE++L + YS +VD W+ G + E+L +P F G E
Sbjct: 247 APEIVL-YQPYSKSVDWWAYGVLLFEMLAGQPPFDGEDE 360
>21578
Length = 524
Score = 63.9 bits (154), Expect = 2e-10, Method: Composition-based stats.
Identities = 26/33 (78%), Positives = 31/33 (93%)
Frame = +2
Query: 369 LKQELPKYLPALQGCRSVEEFQCLNRIEEGTYG 401
LK++LP YLPA+QGCR+VEEF C+NRIEEGTYG
Sbjct: 425 LKEDLPVYLPAIQGCRNVEEFHCMNRIEEGTYG 523
>27546
Length = 426
Score = 62.8 bits (151), Expect = 4e-10, Method: Composition-based stats.
Identities = 38/113 (33%), Positives = 60/113 (53%), Gaps = 2/113 (1%)
Frame = -1
Query: 426 KEGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQ-- 483
K+ FP RE+ + + HPNI+ + I+ KI+I M Y E ++ +K+
Sbjct: 348 KKFFP----RELEILTRLDHPNIIQIHSIL--QRGPKIFIFMRYAEKG--DMLSHIKKTG 193
Query: 484 PFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAR 536
P + K Q+ + +++LH + I HRDLK N+LLS +K+ DFG AR
Sbjct: 192 PIDEAQTKVWFFQMAKALQYLHSHDIAHRDLKCENILLSKRLNVKIADFGFAR 34
>14116
Length = 1017
Score = 62.0 bits (149), Expect = 9e-10, Method: Compositional matrix adjust.
Identities = 61/205 (29%), Positives = 99/205 (48%), Gaps = 14/205 (6%)
Frame = -1
Query: 395 IEEGTYGVVYRA----KDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVT 450
I +G +G V R ++K D +VA+K L +E + L+E + H N++T
Sbjct: 612 IGKGNFGCVKRGFLTLPEQKGDILVAVKTLHNNNPREIELQSFLQEALIMKDFHHSNVLT 433
Query: 451 VREIVVGSNMDKI-YIVMNYVEHD--LKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDN 507
+ I + N+D + +V+ +++H L + + QP + ++ + + RG+ +L
Sbjct: 432 LIGICL--NLDDMPLVVLPFMKHGDLLTYIRDDQHQPTIK-DLIMYGVDIARGMDYLAGL 262
Query: 508 WILHRDLKTSNLLLSHAGILKVGDFGLAR-----EYGSP--LKAYTPVVVTQWYRAPELL 560
+HRDL N +L +KV DFGLAR EY S KA PV +W L
Sbjct: 261 KFVHRDLAARNCMLDEDFHVKVADFGLARDIYEKEYYSSENKKAKLPV---KWMALESLE 91
Query: 561 LGAKEYSTAVDMWSVGCIFGELLTQ 585
G Y + D+WS G + ELLT+
Sbjct: 90 KG--NYDSKTDVWSYGVVLWELLTR 22
>03240
Length = 1683
Score = 61.6 bits (148), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 62/262 (23%), Positives = 105/262 (40%), Gaps = 48/262 (18%)
Frame = -3
Query: 389 FQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNI 448
F+ + + G +G V + T + A+K L+ + + ++ IL A+ N
Sbjct: 1285 FEKIKTLGVGAFGEVSLCRKNDTGMLYAMKTLRKSDVLKRNQVAHVKAERDIL-AEADNE 1109
Query: 449 VTVREIVVGSNMDKIYIVMNYVEH-DLKSL---METMKQPFLPGEVKTLMIQLLRGVKHL 504
V+ + + +Y VM+YV DL L ME + +P + + +L++ ++ +
Sbjct: 1108 WVVKLYYSFQDHNYLYFVMDYVPGGDLMGLLIRMEILDEPL----ARFYVAELVQAIESV 941
Query: 505 HDNWILHRDLKTSNLLLSHAGILKVGDFGL-------------------AREYGSPLKAY 545
H +HRD+K N+L+ G +K+ DFGL AR+ +K
Sbjct: 940 HRMGFIHRDIKPDNILIDRNGHIKLTDFGLCTGFRWTHNSKYYQRDGTHARQDSMEVKCQ 761
Query: 546 T-------------------------PVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFG 580
+V T Y APE+L Y++ D WSVG I
Sbjct: 760 LDEQCQCEILKPLERRRKREQRCLAHSLVGTPNYIAPEVLSRLGGYTSVCDWWSVGVILF 581
Query: 581 ELLTQKPLFPGNSEIDQINKVF 602
E+L P F N+ + KV
Sbjct: 580 EMLVGHPPFYANTPAETQYKVI 515
>30755
Length = 1137
Score = 61.2 bits (147), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 35/94 (37%), Positives = 51/94 (54%), Gaps = 3/94 (3%)
Frame = +2
Query: 496 QLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLARE---YGSPLKAYTPVVVTQ 552
+++ + +LH I++RDLK NLLL G +KV DFGL +E YG K + T
Sbjct: 56 EIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCKEDITYGRTTKTFCG---TP 226
Query: 553 WYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQK 586
Y APE +L +Y AVD W G + E++ +
Sbjct: 227 EYLAPE-VLDDNDYGRAVDWWGTGVVMYEMICGR 325
>13212
Length = 1067
Score = 61.2 bits (147), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 46/206 (22%), Positives = 93/206 (45%), Gaps = 4/206 (1%)
Frame = -1
Query: 474 LKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFG 533
L S+M +++P ++ + ++ + LH + ++HRD+K N+LL+ G +K+ DFG
Sbjct: 1022 LDSIMVDLEKPMTEAQICYVCHEMCMALDFLHRHHVIHRDIKAGNVLLTIDGEVKLADFG 843
Query: 534 LAREYGSPLKAYTPVVVTQWYRAPELLLGA----KEYSTAVDMWSVGCIFGELLTQKPLF 589
++ + + + T ++ APE++L Y D+WS+G E
Sbjct: 842 VSAKNTQTQQKRDTFIGTPYWMAPEVVLCETLKDTPYDFKADIWSLGVTLIE-------- 687
Query: 590 PGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKMTFSEHPYNNLRKRFGALLSDQGFD 649
F ++ P++++ P + V+ K+ S+ P K++ L D
Sbjct: 686 ------------FAQIEPPNKEMHP----MRVLIKIHKSDPPTLEKPKKWTKLFK----D 567
Query: 650 LMNKFLTYFPGRRISAEDGLKHEYFR 675
+ K L P R +A + L+H + +
Sbjct: 566 FIAKCLVKDPNLRPTAAELLEHPFMK 489
>28638
Length = 1458
Score = 60.8 bits (146), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 33/81 (40%), Positives = 51/81 (62%), Gaps = 2/81 (2%)
Frame = -1
Query: 509 ILHRDLKTSNLLLSHA--GILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEY 566
I+H DLK N+LL + +K+ DFG + + G + Y + +++YR+PE+LLG Y
Sbjct: 768 IIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQY---IQSRFYRSPEVLLGVP-Y 601
Query: 567 STAVDMWSVGCIFGELLTQKP 587
A+DMWS+GCI E+ T +P
Sbjct: 600 DLAIDMWSLGCILVEMHTGEP 538
Score = 30.0 bits (66), Expect = 3.9, Method: Compositional matrix adjust.
Identities = 15/52 (28%), Positives = 22/52 (42%), Gaps = 5/52 (9%)
Frame = -2
Query: 566 YSTAVDMWSVGC-----IFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKI 612
Y W + C + PLF G++E DQ+ K+ + LG P I
Sbjct: 617 YXXCPMTWPLTCGXWAVYWWRCTXGNPLFAGSNEFDQMMKIVEVLGVPPRHI 462
>13066
Length = 551
Score = 60.5 bits (145), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 52/188 (27%), Positives = 88/188 (46%), Gaps = 6/188 (3%)
Frame = +3
Query: 395 IEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREI 454
+ GT+ Y K +I+ ++ ++ ++ FP RE++ + K HP I+ + I
Sbjct: 15 VVHGTFNDGYGRNIKLACKIIDKEKAPVDFVEKFFP----RELDLLTKLDHPYIIQIHSI 182
Query: 455 VVGSNMDKIYIVMNYVEH-DLKSLMETMKQPFLP-GEVKTLMIQLLRGVKHLHDNWILHR 512
+ K +I M + E DL + ++ + F+ + K Q+ + +LH + HR
Sbjct: 183 L--QRXPKNFIFMRFAERGDLLTYIQEVG--FVKEKQAKIWFYQMTTALNYLHSYDVAHR 350
Query: 513 DLKTSNLLLSHAGILKVGDFGLA----REYGSPLKAYTPVVVTQWYRAPELLLGAKEYST 568
DLK N+LLS +K+ DFG A E G + T + Y APE++ GA
Sbjct: 351 DLKCENILLSSHFNVKLADFGFACACITESGEKYMSRT-YCGSAAYAAPEIVYGAPYAPK 527
Query: 569 AVDMWSVG 576
D WS+G
Sbjct: 528 VADAWSLG 551
>26909
Length = 394
Score = 60.1 bits (144), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 38/119 (31%), Positives = 57/119 (47%), Gaps = 16/119 (13%)
Frame = +2
Query: 578 IFGELLTQKPLFPGNSEI---------DQINKVFKELGTPSEKIWPGYSELPVVKKMT-- 626
IF ELLT +P+F E DQ++++F +G P EK W +P +++T
Sbjct: 2 IFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFPQEKDWEDIRRMPEHQQLTKD 181
Query: 627 FSEHPYNNLR-----KRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLP 680
F Y N ++ + F L+ K LT P +RI++E +K YF E PLP
Sbjct: 182 FKRSSYVNCNLMKYMEKHKVKADSKAFHLLQKLLTMDPVKRITSEQAMKDPYFLEEPLP 358
>19094
Length = 898
Score = 58.9 bits (141), Expect = 8e-09, Method: Compositional matrix adjust.
Identities = 31/105 (29%), Positives = 58/105 (55%), Gaps = 2/105 (1%)
Frame = +1
Query: 474 LKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFG 533
+ +M + + E+ T++ L+G+ +LH +HRD+K N+LL++ G K+ DFG
Sbjct: 16 VSDIMRLRNKTLVEREIATILYYTLKGL*YLHSRRKIHRDIKAGNILLNNEGHAKLADFG 195
Query: 534 LAREYGSPLKAYTPVVVTQWYRAPELL--LGAKEYSTAVDMWSVG 576
+A + + V+ T ++ APE++ +G Y D+WS+G
Sbjct: 196 VAGQLTDTMAKRNTVIGTPYWMAPEVIQEIG---YDCVADIWSLG 321
>21808
Length = 1011
Score = 58.2 bits (139), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 56/201 (27%), Positives = 96/201 (47%), Gaps = 14/201 (6%)
Frame = +1
Query: 415 VALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDL 474
VA+K LK P L E + K +HP ++ + V + D I+I+ +++
Sbjct: 28 VAIKTLKSGTMD---PKDFLAEAQIMKKLRHPKLIQL--YAVCTQDDPIFIITELMKNG- 189
Query: 475 KSLMETMKQPFLPGEVKTLMI--------QLLRGVKHLHDNWILHRDLKTSNLLLSHAGI 526
SL+E FL G+ + L + Q+ G+ +L +HRDL N+L+S
Sbjct: 190 -SLLE-----FLQGKGRVLKLPALIDIGAQIACGMAYLESQNYIHRDLAARNILVSDNNT 351
Query: 527 LKVGDFGLAR-----EYGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGE 581
+K+ DFGLAR EY + + A P+ +W APE ++ D+WS G + E
Sbjct: 352 VKIADFGLARVIKEDEYEARVGARFPI---KW-TAPE-AANYNRFTIKSDVWSFGILLTE 516
Query: 582 LLTQKPL-FPGNSEIDQINKV 601
+T + +PG + + +++V
Sbjct: 517 TVTYGRVPYPGMTNAEVLHQV 579
>11185
Length = 473
Score = 56.6 bits (135), Expect = 4e-08, Method: Compositional matrix adjust.
Identities = 35/117 (29%), Positives = 56/117 (47%), Gaps = 22/117 (18%)
Frame = +1
Query: 490 VKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAY---- 545
++ I L+ G+ ++H IL DL+ S +LL +G+LK DFGL++ G L+
Sbjct: 7 IRDFGIHLVTGLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKF 186
Query: 546 ------------------TPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLT 584
P + Y APE+ GA E S D+W++GC+F E+ +
Sbjct: 187 AEAGDQWNIQSAEEMMKQVPTSGSPTYMAPEVFQGA-EPSIMSDLWALGCVFYEMFS 354
>19301
Length = 712
Score = 55.8 bits (133), Expect = 6e-08, Method: Compositional matrix adjust.
Identities = 43/149 (28%), Positives = 75/149 (50%), Gaps = 2/149 (1%)
Frame = +2
Query: 387 EEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHP 446
E L + G G V+ K E VA+K+++ KE + I +LR++N HP
Sbjct: 305 ESITDLEWLGSGAQGAVFLGK--LCAEEVAVKKVRDIKETD---IRNLRKLN------HP 451
Query: 447 NIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMK--QPFLPGEVKTLMIQLLRGVKHL 504
NI++ + + + I+M Y + L E ++ + P V Q+ G+ +L
Sbjct: 452 NIISFKGVC--TQAPCYCIIMEYCPY--GQLYEVLRDGKEIPPALVLDWSKQIASGMNYL 619
Query: 505 HDNWILHRDLKTSNLLLSHAGILKVGDFG 533
H + I+HRDLK+ N+L++ ++K+ DFG
Sbjct: 620 HSHKIIHRDLKSPNVLVAKNDVVKISDFG 706
>27405
Length = 532
Score = 55.8 bits (133), Expect = 6e-08, Method: Compositional matrix adjust.
Identities = 28/89 (31%), Positives = 52/89 (58%)
Frame = -3
Query: 485 FLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKA 544
F EV+ +++ G++H+H ++++RDLK +N+LL G +++ D GLA ++ K
Sbjct: 263 FTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGLACDFSK--KK 90
Query: 545 YTPVVVTQWYRAPELLLGAKEYSTAVDMW 573
V T Y APE+L+ + Y ++ D +
Sbjct: 89 PHASVGTHGYMAPEVLMKGQAYDSSADWF 3
>07940
Length = 1336
Score = 55.8 bits (133), Expect = 7e-08, Method: Compositional matrix adjust.
Identities = 35/112 (31%), Positives = 56/112 (50%), Gaps = 6/112 (5%)
Frame = -3
Query: 479 ETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLARE- 537
+ M + P ++ + Q+ RG+++L +HRDL N+L++ +LK+ DFGL R
Sbjct: 374 QDMLKMLTPKDLISYAYQVARGMEYLASKQCIHRDLAARNVLVAEEYVLKIADFGLTRNL 195
Query: 538 -----YGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLT 584
Y PV +W APE L K Y++ D+WS G + E+ T
Sbjct: 194 QQFDYYRKTTDGRLPV---KW-MAPEALFDRK-YTSKSDVWSYGVLLWEIFT 54
>18287
Length = 678
Score = 55.5 bits (132), Expect = 8e-08, Method: Composition-based stats.
Identities = 35/119 (29%), Positives = 53/119 (44%), Gaps = 8/119 (6%)
Frame = -3
Query: 566 YSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKM 625
Y ++D+WSVGCIF ELL+++ LF + Q++ + +GTP + E
Sbjct: 673 YDYSIDIWSVGCIFAELLSRRILFQAQGPVQQLDMIINLVGTPRPEDMERACE------- 515
Query: 626 TFSEHPYNNLRKRFGALL--------SDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 676
H N +R L + + L+ + L P RISAE+ L H Y E
Sbjct: 514 GARNHILNQPFRRQNLLTLYNLSPHATHEAVRLLTRMLILNPKNRISAEEALSHPYLDE 338
>26711
Length = 405
Score = 55.5 bits (132), Expect = 8e-08, Method: Composition-based stats.
Identities = 39/111 (35%), Positives = 61/111 (54%), Gaps = 6/111 (5%)
Frame = -2
Query: 496 QLLRGVKHLHDNWILHRDLKTSNLLLSHAGI--LKVGDFGLAREYGSPLKAY----TPVV 549
Q+L ++H+H ++H DLK SNLLLS + +++ DFGLAR+ P + + TP
Sbjct: 392 QVLDILQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARKLYPPQETFLNHGTP-- 219
Query: 550 VTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINK 600
+ +PE L K STA D+W VG + LL+ + F +S + + K
Sbjct: 218 ---GFTSPE-ALDVKPISTASDVWGVGVLAYILLSGQSPFQADSATESLKK 78
>24241
Length = 413
Score = 55.1 bits (131), Expect = 9e-08, Method: Compositional matrix adjust.
Identities = 25/84 (29%), Positives = 54/84 (64%)
Frame = -2
Query: 392 LNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTV 451
L++I EGTYGVVY+ + + T +A+K++++ ++G P +++REI + + +H +
Sbjct: 328 LSKIGEGTYGVVYKCRHRATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTQXLVC 149
Query: 452 REIVVGSNMDKIYIVMNYVEHDLK 475
E V+ + +++++V ++ DLK
Sbjct: 148 LEDVIMED-ERLFLVFEFLSMDLK 80
>28157
Length = 400
Score = 55.1 bits (131), Expect = 1e-07, Method: Composition-based stats.
Identities = 44/129 (34%), Positives = 67/129 (51%), Gaps = 8/129 (6%)
Frame = +3
Query: 415 VALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSNMDK-IYIVMNYVEHD 473
VA+KR++ E+EK+ F ++E+ + + HPNIV + G+ D + +VM Y E
Sbjct: 9 VAVKRIESEQEKKSF----MQELKQLSRVSHPNIVCL----YGACRDHPVCLVMEYAEGG 164
Query: 474 --LKSLMETMKQP-FLPGEVKTLMIQLLRGVKHLHD---NWILHRDLKTSNLLLSHAGI- 526
L + QP + ++Q GV++LH ++HRDLK NLLL G
Sbjct: 165 SLYNVLHGSGPQPQYTAAHAMNWLLQCALGVEYLHGMKPKALIHRDLKPPNLLLIQCGTK 344
Query: 527 LKVGDFGLA 535
LK+ DFG A
Sbjct: 345 LKICDFGTA 371
>31489
Length = 329
Score = 54.7 bits (130), Expect = 1e-07, Method: Composition-based stats.
Identities = 28/81 (34%), Positives = 50/81 (61%), Gaps = 4/81 (4%)
Frame = +3
Query: 444 QHPNIVTVREIVVGSN----MDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLR 499
+H NI+++REI+ + I++V + +E DL ++ + QP ++ + Q+LR
Sbjct: 24 KHDNIISIREILKPKDSYHDFKDIHVVFDLMESDLHRIIYS-DQPLTEEHIRYFLYQILR 200
Query: 500 GVKHLHDNWILHRDLKTSNLL 520
G+K++H ++HRDLK SNLL
Sbjct: 201 GLKYIHSANVVHRDLKPSNLL 263
>12672
Length = 773
Score = 53.5 bits (127), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 31/89 (34%), Positives = 50/89 (56%), Gaps = 4/89 (4%)
Frame = +3
Query: 500 GVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREY----GSPLKAYTPVVVTQWYR 555
G+++L+DN +HRD+KT+N+LL KVGDF G ++ + V+ T Y
Sbjct: 27 GIQYLNDNGHVHRDIKTANILLDSEYTAKVGDFATVVSAPSGEGKTVQNASVVIGTAAYL 206
Query: 556 APELLLGAKEYSTAVDMWSVGCIFGELLT 584
APE + + ST +D +S G + E++T
Sbjct: 207 APEAI--HFDVSTKLDSYSFGVVLLEVIT 287
>17253
Length = 483
Score = 53.1 bits (126), Expect = 4e-07, Method: Composition-based stats.
Identities = 44/140 (31%), Positives = 67/140 (47%), Gaps = 14/140 (10%)
Frame = -1
Query: 423 EKEKEGFPITSLREINTILK-AQHPNIVTVREIVVGSNMDKIYIVMNYVEH-DLKSLMET 480
+ EK F LRE++ + K +HPN+V+ S D I+M + H DL S +
Sbjct: 426 DAEKSEF----LRELSIMRKLPRHPNVVSFMGCCTMS--DPALILMEFCCHGDLLSFLRK 265
Query: 481 MKQP----FLPGEVKTLM--------IQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILK 528
++P FL L + + RG+ H+ +N I+HRD+ N+L+S + K
Sbjct: 264 -RRPDRTVFLTSTANDLTARDFFSFALHVARGMAHVANNKIVHRDVAARNVLISERNVCK 88
Query: 529 VGDFGLAREYGSPLKAYTPV 548
V DFGL+R G Y V
Sbjct: 87 VSDFGLSRRVGDQNDVYEIV 28
>04852
Length = 1462
Score = 52.8 bits (125), Expect = 5e-07, Method: Compositional matrix adjust.
Identities = 30/90 (33%), Positives = 48/90 (53%)
Frame = +1
Query: 495 IQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWY 554
Q+ RG++ L +HRDL N+L++ +LK+ DFGL+R K + +W
Sbjct: 346 FQIARGMEFLASRKCIHRDLAARNVLVTEEHVLKIADFGLSRTGDYYKKRSGGRLPVKWM 525
Query: 555 RAPELLLGAKEYSTAVDMWSVGCIFGELLT 584
APE L + Y+T D+WS G + E+ +
Sbjct: 526 -APEALFDMR-YTTKSDVWSFGVVLWEIFS 609
>00715
Length = 1788
Score = 52.0 bits (123), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 48/177 (27%), Positives = 84/177 (47%), Gaps = 29/177 (16%)
Frame = +1
Query: 444 QHPNIVTVREIVVGSNM-----DKIYIVMNYV-EHDLKSLMETMKQPFLPGEVKTLMIQL 497
+H N+V++ +G+ D ++ M YV +L++++ +Q +L +Q+
Sbjct: 100 RHVNVVSI----LGATSLHRFEDGAWLAMEYVGPLNLQTILNDHQQDIDSSMRLSLALQM 267
Query: 498 LRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREY---------------GSPL 542
RG+ +LH I+H DLK +N LL+ L++ DFG + G+ L
Sbjct: 268 ARGLHYLHSINIVHLDLKPANCLLTRDLKLRIADFGCCHQLTPTGLDMGEREGGMAGNEL 447
Query: 543 KAYTPV--------VVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPG 591
+ TPV T YRAPELL G + S D++S+G ++ T++ + G
Sbjct: 448 E-LTPVQGAWKNELAGTLAYRAPELLKGLQP-SVRSDVYSLGITLWQMCTRQGPYEG 612
>18401
Length = 463
Score = 51.6 bits (122), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 39/144 (27%), Positives = 66/144 (45%), Gaps = 14/144 (9%)
Frame = -3
Query: 545 YTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKE 604
++ +V T+ YRAPE++L +S D+WSVGCI EL T LF + + + + +
Sbjct: 461 HSTIVSTRHYRAPEVILELG-WSHPCDVWSVGCIMFELYTGYTLFQTHDNKEHLAMMERI 285
Query: 605 LGTPSEKI--------WPGYSELPVVKKMTFSEHPYNNLRKRFGALLS------DQGFDL 650
LG+ ++ + + L V ++ + + + N + + Q FDL
Sbjct: 284 LGSLPYRMAKKTKKQKYFHHGRLDVPERSSMARYVRENTKPLLRYVKDRENKDHQQLFDL 105
Query: 651 MNKFLTYFPGRRISAEDGLKHEYF 674
M K L Y R S L+H +F
Sbjct: 104 MKKLLAYEASSRYSLLQALQHPFF 33
>21079
Length = 878
Score = 50.8 bits (120), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 34/91 (37%), Positives = 50/91 (54%), Gaps = 2/91 (2%)
Frame = +1
Query: 496 QLLRGVKHLHDNWILHRDLKTSNLLL--SHAGILKVGDFGLAREYGSPLKAYTPVVVTQW 553
Q+ GV ++H ILH DLK N+L ++ +K+ DFGLAR Y P + + T
Sbjct: 151 QICSGVGYMHTQSILHLDLKPENVLCVSDNSNQIKIIDFGLARFY-KPGDSLQVLFGTPE 327
Query: 554 YRAPELLLGAKEYSTAVDMWSVGCIFGELLT 584
+ APE ++ E + DMWS+G I LL+
Sbjct: 328 FIAPE-VVNYDEINFTTDMWSIGVICYILLS 417
>16003
Length = 926
Score = 50.8 bits (120), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 35/99 (35%), Positives = 51/99 (51%)
Frame = -1
Query: 582 LLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKMTFSEHPYNNLRKRFGA 641
LL + P PG++++DQ+ K+F LGTP+E WP + LP + F L++ F A
Sbjct: 926 LLIRLPFLPGDTDLDQLGKIFNMLGTPTETEWPAVTSLP--DYIQFKHCQKQPLKEIFTA 753
Query: 642 LLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLP 680
D +L++K L P R +A LK YF P P
Sbjct: 752 -AGDDLLELLDKLLAMNPLHRCTATQALKMPYFSNKPYP 639
>00392
Length = 668
Score = 50.1 bits (118), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 46/163 (28%), Positives = 74/163 (45%), Gaps = 6/163 (3%)
Frame = +3
Query: 444 QHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTL---MIQLLRG 500
QHPNIV + N +++ E ++T + F VK L Q+L+G
Sbjct: 105 QHPNIVRFFDYWEEHNHRNRKVIILVTELMTSGTLKTYLKRFKKPNVKILKNWCRQVLKG 284
Query: 501 VKHLHDNW--ILHRDLKTSNLLLSH-AGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAP 557
+ LH ++HRDLK N+ ++ G +K+GD GLA V+ T + AP
Sbjct: 285 LYFLHTRTPPVIHRDLKCDNIFITGPTGSVKIGDLGLATLKNQSFAK--SVIGTPEFMAP 458
Query: 558 ELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINK 600
E+ + Y AVD+++ G E+ + + + S QI K
Sbjct: 459 EMY--EEHYDEAVDVYAFGMCMLEMASSEYPYSECSNAAQIYK 581
>12786
Length = 460
Score = 50.1 bits (118), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 38/117 (32%), Positives = 58/117 (49%), Gaps = 23/117 (19%)
Frame = -3
Query: 496 QLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLA----REYGSPLKAYTPVVVT 551
++LR VK LH+ ++H DLK +N +L AG LK+ DFG+A ++ S LK V T
Sbjct: 386 EMLRAVKALHNEGVIHSDLKPANFMLV-AGNLKLIDFGIANTLQQDKTSVLK--DSRVGT 216
Query: 552 QWYRAPELLLGAKE-----------------YSTAV--DMWSVGCIFGELLTQKPLF 589
Y +PE ++ A + Y V D+WS+GCI ++ + F
Sbjct: 215 PSYMSPEAIMAACDDSADDSMEEDGHRTKPKYKVGVRSDVWSLGCILYNMVYGRTPF 45
>17300
Length = 480
Score = 49.7 bits (117), Expect = 4e-06, Method: Composition-based stats.
Identities = 31/90 (34%), Positives = 51/90 (56%), Gaps = 5/90 (5%)
Frame = +1
Query: 500 GVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLK--AYTP---VVVTQWY 554
G+ L D +HRDL N+L++ + KV DFGL+RE S AYT + +W
Sbjct: 10 GMGXLADMGYVHRDLAARNILVNEILVCKVADFGLSREIESDTTEGAYTTKGGKIPVRW- 186
Query: 555 RAPELLLGAKEYSTAVDMWSVGCIFGELLT 584
APE + +++++A D+WS G + E+++
Sbjct: 187 TAPE-AIAYRKFTSASDVWSFGVVMWEVMS 273
>31885
Length = 529
Score = 47.4 bits (111), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 46/161 (28%), Positives = 73/161 (45%), Gaps = 4/161 (2%)
Frame = -2
Query: 437 INTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQ 496
++ + + HP +V + D +V ++ DL+ M+ + F VK + Q
Sbjct: 519 VDMLTRLDHPFLVNLW-YAFQDEEDLFMVVDLFLGGDLRYHMQQ-EVSFREDCVKFYLCQ 346
Query: 497 LLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRA 556
L + +L I+HRD+K N+LL G V DF +A + A T T+ Y A
Sbjct: 345 LALVLDYLRSQKIVHRDIKPDNILLDEQGHCHVTDFNIATQLEDDELA-TSTSGTRPYMA 169
Query: 557 PELLLGA----KEYSTAVDMWSVGCIFGELLTQKPLFPGNS 593
PE+ A + Y VD WS+G ELL ++ F +S
Sbjct: 168 PEVYGVAINERRGYGFPVDWWSLGVSLFELLKKRRPFSVHS 46
>11780
Length = 1713
Score = 46.2 bits (108), Expect = 5e-05, Method: Compositional matrix adjust.
Identities = 51/202 (25%), Positives = 98/202 (48%), Gaps = 4/202 (1%)
Frame = +3
Query: 395 IEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREI 454
I +G +G VY+ + + VA+K+LK +K+ + L+E + + +H N+V + +
Sbjct: 621 IGKGDFGDVYKGMYR--GQPVAIKQLK---DKDRGEQSFLQEASVMTSLRHDNLVRLIGV 785
Query: 455 VVGSNMDKIYIVMNYV-EHDLKSLMETMKQPFLPGEVK-TLMIQLLRGVKHLHDNWILHR 512
V+G + I++V ++ + +L + + + + + + +++L ++HR
Sbjct: 786 VLG---ETIFLVTEFMGKGNLVEYLRSRGRSVITKKDQINFATDTCAAMEYLESKRLVHR 956
Query: 513 DLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEY--STAV 570
DL N+L+ G KV DFGLA+ +G + T V + APE L K + V
Sbjct: 957 DLAARNVLVHDDGKAKVSDFGLAK-FGDF--SQTSVKFPIKWTAPEALRENKIH*QVRHV 1127
Query: 571 DMWSVGCIFGELLTQKPLFPGN 592
++W + + G LL P N
Sbjct: 1128ELWHI--VMGNLLLWSSALP*N 1187
>05084
Length = 1324
Score = 45.1 bits (105), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 28/92 (30%), Positives = 43/92 (46%), Gaps = 4/92 (4%)
Frame = +2
Query: 589 FPGNSEIDQINKVFKELGTPS----EKIWPGYSELPVVKKMTFSEHPYNNLRKRFGALLS 644
PG+S +DQ+ ++ K LGTP+ ++ P YSE K HP+ K F
Sbjct: 2 LPGDSGVDQLVEIIKVLGTPTREQIREMNPNYSEF---KFPQIKAHPWT---KVFRPRTP 163
Query: 645 DQGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 676
+ L+++ L Y P RI + H +F E
Sbjct: 164 PEAIQLVSRLLEYTPSARIQPMEACAHAFFDE 259
>20640
Length = 1492
Score = 44.3 bits (103), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 26/79 (32%), Positives = 40/79 (50%), Gaps = 4/79 (5%)
Frame = +1
Query: 510 LHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYT----PVVVTQWYRAPELLLGAKE 565
+HRDL T N L+ H ++K+ DFGLAR S + Y + +W +L +
Sbjct: 10 VHRDLATRNCLVGHDLVVKISDFGLARSVHS-VDYYRGSEHDAIPIRWMPLEAILYN--K 180
Query: 566 YSTAVDMWSVGCIFGELLT 584
+ST D+WS G + E+
Sbjct: 181 FSTQSDVWSFGVVLWEIFA 237
>07836
Length = 1478
Score = 43.5 bits (101), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 53/190 (27%), Positives = 85/190 (44%), Gaps = 20/190 (10%)
Frame = -1
Query: 413 EIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIV--TVREIVVGSNMDKIYIVMNYV 470
E VA+K +E F T L + T+L +H NI+ +I + +++++ +Y
Sbjct: 1475 ENVAVKIFFTTEEASWFRETELYQ--TVL-LRHENILGFIAADIKGTGSWTQLFLITDY- 1308
Query: 471 EHDLKSLMETMKQPFL-PGEVKTLMIQLLRGVKHLHDNW--------ILHRDLKTSNLLL 521
H+ SL + + L E+ L + G+ HLH I HRD+K+ N+L+
Sbjct: 1307 -HENGSLHDYLLSRVLDSSEMLALAHSAICGLAHLHIEIFGTRGKPAIAHRDIKSKNILV 1131
Query: 522 SHAGILKVGDFGLAREYGSPLK----AYTPVVVTQWYRAP---ELLLGAKEYST--AVDM 572
G + D GLA Y S A P T+ Y AP E+LL K + DM
Sbjct: 1130 KKNGTCCIADLGLAVRYISESNEVDVAPNPRQGTKRYMAPEVLEMLLNVKNFDAFKQADM 951
Query: 573 WSVGCIFGEL 582
++ G + E+
Sbjct: 950 YAFGLVMWEI 921
>17975
Length = 449
Score = 43.5 bits (101), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 35/146 (23%), Positives = 67/146 (45%), Gaps = 10/146 (6%)
Frame = +3
Query: 400 YGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSN 459
+ VV A+ T E VA+K + K E +E+ + QHPN+V + E++
Sbjct: 6 FAVVKLARHVFTGEKVAVKVIDKTKLDEVSRSHLFQEVRCMKLVQHPNVVRLYEVI--DT 179
Query: 460 MDKIYIVM---------NYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWIL 510
K+Y+++ +Y+ L E + + + Q++ + + H ++
Sbjct: 180 QTKLYLILELGDGGDMYDYIMRHSGGLEEKLAKRYFR--------QIVEAISYCHKLHVV 335
Query: 511 HRDLKTSNLLLSHA-GILKVGDFGLA 535
HRDLK N++ G++K+ DFG +
Sbjct: 336 HRDLKPENVVFFEKPGLVKLTDFGFS 413
>21433
Length = 590
Score = 42.0 bits (97), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 33/94 (35%), Positives = 50/94 (53%)
Frame = +2
Query: 494 MIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQW 553
+ QL +++ H ++HRD+K NLLL G LK+ DFG + +P T + T
Sbjct: 185 IYQLSSALEYCHYRKVIHRDIKPENLLLGLKGDLKIADFGWSVH--APSSRRTTMCGTLD 358
Query: 554 YRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKP 587
Y PE++ G K + VD+WS+G + E L P
Sbjct: 359 YLPPEMVEG-KTHDENVDLWSLGVLCYEFLVGTP 457
>07291
Length = 833
Score = 41.6 bits (96), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 28/96 (29%), Positives = 50/96 (52%), Gaps = 6/96 (6%)
Frame = +1
Query: 496 QLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGS--PLKAYT----PVV 549
Q+ G+ +L + ++HR+L N +++ G L++ D+G+ GS P YT P
Sbjct: 73 QIADGMAYLQEVKVVHRNLAARNCIVTEDGRLQLSDYGVT---GSLFPQSYYTADDSPAR 243
Query: 550 VTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQ 585
+ APE + +S+ D+W+ G + ELLT+
Sbjct: 244 DLVKWMAPE-TIDNFHFSSKSDVWAFGVVLWELLTR 348
>15549
Length = 470
Score = 40.4 bits (93), Expect = 0.002, Method: Composition-based stats.
Identities = 18/54 (33%), Positives = 35/54 (64%), Gaps = 1/54 (1%)
Frame = -1
Query: 373 LPKYLPALQ-GCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKE 425
LP P+ + R +EF+C+ ++ +G YG+V+RAK+K ++ A+KR+ + +
Sbjct: 263 LPDKAPSAEFKSRFADEFECIEQMGKGGYGIVFRAKNKVDEQEYAVKRIALPSD 102
>02638
Length = 1490
Score = 39.3 bits (90), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 18/50 (36%), Positives = 30/50 (60%)
Frame = +1
Query: 554 YRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFK 603
+ APE+L G + Y A D+WSVGC+ E+ T +P + + + + +FK
Sbjct: 34 FMAPEVLRG-ESYGRACDVWSVGCVMIEMCTCRPPWNSHDISNHLALIFK 180
>14477
Length = 493
Score = 39.3 bits (90), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 41/147 (27%), Positives = 70/147 (47%), Gaps = 4/147 (2%)
Frame = -1
Query: 394 RIEEGTYGVVYRAKDKKTD-EI-VALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTV 451
++ G +G V + + D EI VA+K LK ++E + K H +IV +
Sbjct: 469 KLGAGNFGSVMKGVCRLDDREIPVAIKVLKNADLDPSVQSELIKEAEVMKKMDHMHIVRL 290
Query: 452 REIVVGSNMDKIYIVMNYVEHDLKSLMETM-KQPFLP-GEVKTLMIQLLRGVKHLHDNWI 509
+ G M +V+ + L L + + K LP + LM Q+ +G+++L N
Sbjct: 289 IGLCEGETM---MLVLELAK--LGPLNKFLPKNKHLPLWNILELMWQVSQGMEYLEANKF 125
Query: 510 LHRDLKTSNLLLSHAGILKVGDFGLAR 536
+HRDL N+LL K+ DFG+++
Sbjct: 124 VHRDLAARNILLCDEHFAKISDFGMSK 44
>37602
Length = 804
Score = 38.9 bits (89), Expect = 0.008, Method: Compositional matrix adjust.
Identities = 20/72 (27%), Positives = 39/72 (54%)
Frame = -1
Query: 461 DKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLL 520
+K++I M Y + + P ++ + + L+G+ +LH +HRD+K +N+L
Sbjct: 300 EKLWIAMEYCGGGSMQDIYHVTGPLTEPQIAFVCRETLKGLHYLHRRGKMHRDIKGANIL 121
Query: 521 LSHAGILKVGDF 532
L+ G +K+ DF
Sbjct: 120 LTEEGDVKLADF 85
Score = 28.9 bits (63), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 13/36 (36%), Positives = 21/36 (58%)
Frame = -2
Query: 372 ELPKYLPALQGCRSVEEFQCLNRIEEGTYGVVYRAK 407
E K +Q +++F+ + R+ GTYG VY+AK
Sbjct: 554 EYKKMQADIQRRNPLDDFELIQRVGSGTYGDVYKAK 447
>16708
Length = 1397
Score = 38.9 bits (89), Expect = 0.008, Method: Compositional matrix adjust.
Identities = 16/52 (30%), Positives = 31/52 (59%)
Frame = -1
Query: 487 PGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREY 538
P V + Q + ++H+H+ ++H D+K N+L+ G K+ D+G+A+ Y
Sbjct: 1097 PAMVCCIAGQXVCALEHIHELGVVHMDVKADNVLVDAHGNCKLTDYGIAQLY 942
>26009
Length = 886
Score = 32.0 bits (71), Expect(2) = 0.008, Method: Compositional matrix adjust.
Identities = 12/33 (36%), Positives = 22/33 (66%)
Frame = +3
Query: 489 EVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLL 521
E K++M QL+ + +H ++HRD+K N+L+
Sbjct: 714 EAKSVMKQLVSALDFMHSKQLVHRDIKPENVLI 812
Score = 25.4 bits (54), Expect(2) = 0.008, Method: Compositional matrix adjust.
Identities = 23/93 (24%), Positives = 35/93 (37%), Gaps = 5/93 (5%)
Frame = +2
Query: 387 EEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREIN-----TIL 441
E + + GTYG V A+ + T VALK L T LRE +
Sbjct: 416 EHYDVCKELGRGTYGKVVLARCRHTGTQVALKLLPKS-------CTKLREFQREFQLSYF 574
Query: 442 KAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDL 474
+ H NI+ + + ++ + V DL
Sbjct: 575 LSPHANIIDTYNVAFQTRSSYVFAQEHAVLGDL 673
>13078
Length = 773
Score = 38.1 bits (87), Expect = 0.012, Method: Compositional matrix adjust.
Identities = 31/125 (24%), Positives = 59/125 (47%), Gaps = 14/125 (11%)
Frame = -1
Query: 566 YSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKI--------WPGYS 617
+S D+WS+GCI EL T LF + + + + + LG+ ++ + +
Sbjct: 746 WSQPCDVWSIGCIMFELYTGYTLFQTHDNKEHLAMMERILGSLPYRMAKKTKKQKYFYHG 567
Query: 618 ELPVVKKMTFSEHPYNNLR--KRFGALLSD----QGFDLMNKFLTYFPGRRISAEDGLKH 671
L +K + + +N++ +R+ + Q FDLM+K L+Y R S ++H
Sbjct: 566 RLDWDEKSSAGRYVRDNVKPLRRYVKDPDNEDHQQLFDLMDKMLSYEVSTRYSLRQAMRH 387
Query: 672 EYFRE 676
+FR+
Sbjct: 386 PFFRK 372
>18481
Length = 437
Score = 38.1 bits (87), Expect = 0.013, Method: Compositional matrix adjust.
Identities = 24/77 (31%), Positives = 38/77 (49%), Gaps = 3/77 (3%)
Frame = -1
Query: 465 IVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLS-- 522
+VM + L+ L K+ F + + QLL ++ +H +HRDLK N L+
Sbjct: 266 LVMELLGPSLEELFVICKRRFTLKTILMVSDQLLSRLEFIHQKCFIHRDLKPDNFLMGLG 87
Query: 523 -HAGILKVGDFGLAREY 538
H L + DFGL++ Y
Sbjct: 86 RHCHRLYIIDFGLSKRY 36
>00486
Length = 797
Score = 35.4 bits (80), Expect = 0.079, Method: Compositional matrix adjust.
Identities = 18/50 (36%), Positives = 27/50 (54%)
Frame = -2
Query: 554 YRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFK 603
Y APE+L + AVD WS+G + ++LT P F + I+K+ K
Sbjct: 760 YMAPEILTRTG-HGKAVDWWSLGALMYDMLTGSPPFTAENRKKTIDKILK 614
>36481
Length = 806
Score = 33.1 bits (74), Expect = 0.38, Method: Compositional matrix adjust.
Identities = 37/149 (24%), Positives = 66/149 (44%), Gaps = 6/149 (4%)
Frame = +2
Query: 379 ALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLK-MEKEKEGFPITSLREI 437
++G S + + EGT+G V + KD + +ALK +K ++K +E + EI
Sbjct: 338 TMRGTSSTNDMKLCPHWGEGTFGKVVQCKDLLKGDDIALKIIKNVDKYREAAKL----EI 505
Query: 438 NTILKAQ----HPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGE-VKT 492
N + K + H + V+ + + I + + + ++ P E V+
Sbjct: 506 NVLEKLREKDPHAKHMCVQMLDWFDYHGHVCISFHMLGLSVFDFLKDNSYGAYPIEQVRH 685
Query: 493 LMIQLLRGVKHLHDNWILHRDLKTSNLLL 521
+ QL V LH+N + H DLK N+L
Sbjct: 686 ISYQLCYAVNFLHENQLTHTDLKPENILF 772
>00145
Length = 2325
Score = 30.8 bits (68), Expect = 1.9, Method: Compositional matrix adjust.
Identities = 18/50 (36%), Positives = 25/50 (50%), Gaps = 1/50 (2%)
Frame = -1
Query: 655 LTYFPGRRISAEDGLKHEYFRETP-LPIDPSMFPTWPAKSEQQRVKRGTS 703
+ P RIS DG + RE+P LP D + P P + Q+ V R T+
Sbjct: 2325 IQVHPQHRISQSDGESVDVQRESPLLPRDGAAVPQRPGPAAQEGVSRQTA 2176
>15931
Length = 447
Score = 30.4 bits (67), Expect = 2.5, Method: Compositional matrix adjust.
Identities = 13/31 (41%), Positives = 19/31 (61%)
Frame = +1
Query: 646 QGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 676
Q FDLM+K L+Y R S ++H +FR+
Sbjct: 70 QLFDLMDKMLSYEVSTRYSLRQAMRHPFFRK 162
>20152
Length = 445
Score = 30.0 bits (66), Expect = 3.6, Method: Compositional matrix adjust.
Identities = 14/33 (42%), Positives = 20/33 (60%)
Frame = +1
Query: 557 PELLLGAKEYSTAVDMWSVGCIFGELLTQKPLF 589
PE+LLG + AVD+WS+G I L+ + F
Sbjct: 1 PEILLGDSYDAPAVDVWSLGVILYMLVVGEAPF 99
>38560
Length = 479
Score = 29.3 bits (64), Expect = 6.2, Method: Composition-based stats.
Identities = 12/30 (40%), Positives = 18/30 (60%)
Frame = -3
Query: 554 YRAPELLLGAKEYSTAVDMWSVGCIFGELL 583
Y APEL+ G + + D+WS+G + LL
Sbjct: 387 YAAPELISGLEYLGSEADIWSMGVLLYALL 298
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000367896 | hsapiens_gene_ensembl | PITSLRE
serine/threonine-protein kinase CDC2L2 (EC 2.7.11.22)
(Galactosyltransferase-associated protein kinase p58/GTA) (Cell
division cycle 2-like protein kinase 2) (CDK11).
[Source:Uniprot/SWISSPROT;Acc:Q9UQ88]
(746 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
29581 292 5e-84
01060 229 3e-60
01756 223 3e-58
14126 219 2e-57
04591 196 4e-50
32000 170 2e-42
01707 162 4e-40
04138 151 1e-36
01966 118 3e-28
23319 103 3e-22
00300 95 1e-19
03294 87 2e-17
18921 86 7e-17
06405 83 4e-16
13592 82 6e-16
12721 82 8e-16
01718 80 4e-15
09606 77 2e-14
03508 77 4e-14
20559 66 1e-13
12453 74 2e-13
14420 73 3e-13
15910 71 2e-12
26560 68 1e-11
19761 65 8e-11
18484 65 8e-11
21578 64 2e-10
27546 63 4e-10
14116 62 9e-10
03240 62 1e-09
30755 61 1e-09
13212 61 2e-09
28638 61 2e-09
13066 60 3e-09
26909 60 3e-09
19094 59 8e-09
21808 58 1e-08
11185 57 4e-08
19301 56 6e-08
27405 56 6e-08
07940 56 7e-08
18287 55 8e-08
26711 55 8e-08
24241 55 9e-08
28157 55 1e-07
31489 55 1e-07
12672 54 3e-07
17253 53 4e-07
04852 53 5e-07
00715 52 1e-06
18401 52 1e-06
21079 51 2e-06
16003 51 2e-06
00392 50 3e-06
12786 50 4e-06
17300 50 4e-06
31885 47 2e-05
11780 46 5e-05
05084 45 1e-04
20640 44 2e-04
07836 44 3e-04
17975 44 3e-04
21433 42 0.001
07291 42 0.001
15549 40 0.002
02638 39 0.005
14477 39 0.006
37602 39 0.008
16708 39 0.008
26009 32 0.008
13078 38 0.012
18481 38 0.013
00486 35 0.079
36481 33 0.38
00145 31 1.9
15931 30 2.5
20152 30 3.6
38560 29 6.2
>29581
Length = 1278
Score = 292 bits (747), Expect(2) = 5e-84, Method: Compositional matrix adjust.
Identities = 133/261 (50%), Positives = 183/261 (70%)
Frame = -2
Query: 440 ILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLR 499
+L +H NIV ++E+VVG ++D +++VM Y E DL SL++ M PF +VK +++QLL+
Sbjct: 1193 LLNLRHQNIVQLQEVVVGKSLDSLFLVMEYCEQDLASLLDNMPAPFSESQVKCIVLQLLK 1014
Query: 500 GVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPEL 559
G+++LH+ +I+HRDLK SNLL++ G +K+ DFGLAR YG P K TP VVT WYRAPEL
Sbjct: 1013 GLRYLHEAFIIHRDLKVSNLLMTDKGCVKIADFGLARNYGKPQKPMTPKVVTLWYRAPEL 834
Query: 560 LLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSEL 619
L G+K +STA+DMWS GCI GELL KPL PG S++ QI + + LGTP++ IWPG+S+L
Sbjct: 833 LFGSKTHSTAIDMWSAGCILGELLGHKPLMPGRSDLQQIELIMELLGTPNDTIWPGFSQL 654
Query: 620 PVVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPL 679
P ++ T + PYNNLR F LS+ G L+N Y P +R +AED L+H YF+E P
Sbjct: 653 PAFEQFTLKKQPYNNLRHTF-PWLSESGIRLLNGLFMYHPQKRATAEDCLEHSYFKEQPY 477
Query: 680 PIDPSMFPTWPAKSEQQRVKR 700
P DP P++P Q R+KR
Sbjct: 476 PCDPEFMPSFP----QHRLKR 426
Score = 38.9 bits (89), Expect(2) = 5e-84, Method: Composition-based stats.
Identities = 17/35 (48%), Positives = 25/35 (71%)
Frame = -1
Query: 412 DEIVALKRLKMEKEKEGFPITSLREINTILKAQHP 446
+EIVALK+++M E+ G PI+ LREIN ++ P
Sbjct: 1278 NEIVALKKMRMTGERYGIPISGLREINIFAQSATP 1174
>01060
Length = 1800
Score = 229 bits (584), Expect = 3e-60, Method: Compositional matrix adjust.
Identities = 122/338 (36%), Positives = 204/338 (60%), Gaps = 2/338 (0%)
Frame = +1
Query: 364 LLPIELKQELPKYLPALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKME 423
LL + +K+ + + AL + +FQ +I EGTYGVVY+ + + T +A+K++++
Sbjct: 22 LLKLNIKRLMMDFETALS---DLTDFQ---KIGEGTYGVVYKCRHRATGRKLAMKKIRLR 183
Query: 424 KEKEGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQ 483
++G P +++REI + + +H NIV + ++++ +++++V ++ DLK ++ +
Sbjct: 184 GSEDGVPSSAIREIAMLRELRHTNIVCLEDVIMED--ERLFLVFEFLSMDLKMYIDKFPE 357
Query: 484 PFLPGE--VKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSP 541
+ VK+ + Q++ G+ H I+HRDLK NLL++H G +K+ DFG+AR + P
Sbjct: 358 GVVLDRRLVKSYVFQIVTGIXFCHQRRIVHRDLKPQNLLINHTGAIKIADFGMARTFALP 537
Query: 542 LKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKV 601
++AYT VVT WYRAPE+L+GA +YST VD+WS+G IF ++L + P+F G+SEIDQ+ K+
Sbjct: 538 VRAYTHEVVTLWYRAPEILMGASKYSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKI 717
Query: 602 FKELGTPSEKIWPGYSELPVVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGR 661
F+ +GTP+E+ WP + +LP M F L + L S G DL+ + L P +
Sbjct: 718 FRIIGTPTEQTWPEFHKLPAFNGM-FPLWKEGKLSETLTDLDS-LGLDLIERTLKCDPAQ 891
Query: 662 RISAEDGLKHEYFRETPLPIDPSMFPTWPAKSEQQRVK 699
RIS + L+H YF + P P+ P S R+K
Sbjct: 892 RISCKKMLQHAYFLNVDTSVKPVDVPS-PEHS*STRLK 1002
>01756
Length = 1858
Score = 223 bits (567), Expect = 3e-58, Method: Compositional matrix adjust.
Identities = 117/309 (37%), Positives = 187/309 (60%), Gaps = 10/309 (3%)
Frame = -3
Query: 383 CRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILK 442
C +++ L +I +GT+G V++A+ KKT ++VA+K++ M+ EKEGFPIT+LREI +
Sbjct: 1754 CDEDAKYEKLAKIGQGTFGEVFKARCKKTKQVVAMKKVLMDNEKEGFPITALREIKILQL 1575
Query: 443 AQHPNIVTVREIV----VGSNMDK--IYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQ 496
H N+V + EI +N K Y+V + EHDL L+ M F E+K +M Q
Sbjct: 1574 LNHENVVDLIEICSTKATSANRYKSMFYLVFEFCEHDLAGLLSNMSVVFNLPEIKEVMKQ 1395
Query: 497 LLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKA---YTPVVVTQW 553
L+ G+ ++H N ILHRD+K +N+L++ G+LK+ DFGLAR + L+ YT VVT W
Sbjct: 1394 LMNGLYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLW 1215
Query: 554 YRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIW 613
YR PELLLG + YSTA+D W GCI E+ T+ P+ G +E +Q+ + + G+ + ++W
Sbjct: 1214 YRPPELLLGDRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQNQLTLITQLCGSITPEVW 1035
Query: 614 PGYSELPVVKKMTFSEHPYNNLRKRFGALLSDQ-GFDLMNKFLTYFPGRRISAEDGLKHE 672
PG L + + + +++R + D DL++K L PG+R+++++ L H+
Sbjct: 1034 PGVERLELYNSLDLPQGNKRKVKERLRYYIKDAYALDLLDKLLALDPGKRVNSDEALSHD 855
Query: 673 YFRETPLPI 681
+F P P+
Sbjct: 854 FFWMDPEPL 828
>14126
Length = 1265
Score = 219 bits (559), Expect = 2e-57, Method: Compositional matrix adjust.
Identities = 125/299 (41%), Positives = 182/299 (60%), Gaps = 9/299 (3%)
Frame = +3
Query: 387 EEFQCLNRIEEGTYGVVYRAKD-KKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQ- 444
++++ + I G YG VY+A+D + E VA+KR+++ +EG P+ ++REI+ + + +
Sbjct: 189 QKYEEVAVIGNGAYGTVYKARDLRNQGEFVAMKRIRLNNTEEGMPMMAIREISMLKQLEQ 368
Query: 445 --HPNIVTVREIVVGSNMDK---IYIVMNYVEHDLKSLMETMKQPFL-PGEVKTLMIQLL 498
HPN+V + ++ + D+ + +V Y+EHDL + + P L P +K LM+QLL
Sbjct: 369 YEHPNVVRLLDVSHNTITDREIRLNLVFEYIEHDLATYLAKCPSPGLGPDRIKDLMLQLL 548
Query: 499 RGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPE 558
GV LH N I+HRDLK NLL+S G LK+ DFGLAR Y + A T VVVT WYR+PE
Sbjct: 549 NGVDFLHSNRIVHRDLKPQNLLISKDGRLKLADFGLARIYSFHM-ALTTVVVTLWYRSPE 725
Query: 559 LLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWP-GYS 617
+L+ A EY T+VD+WS GCIF EL T++ LF G+SE DQ+ K+F+ +G P WP G S
Sbjct: 726 VLMQA-EYGTSVDIWSCGCIFAELFTRRALFKGSSEFDQLKKIFEVIGLPPAGDWPEGVS 902
Query: 618 ELPVVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 676
V + +F P L+ + Q DLM K L + GRRIS+ + L H Y R+
Sbjct: 903 ----VHRNSFRPTPPVPLQTLVPE-MDPQAKDLMEKMLVFKSGRRISSRESLLHPYLRD 1064
>04591
Length = 1117
Score = 196 bits (497), Expect = 4e-50, Method: Compositional matrix adjust.
Identities = 102/267 (38%), Positives = 161/267 (60%), Gaps = 7/267 (2%)
Frame = -2
Query: 426 KEGFPITSLREINTILKAQHPNIVTVREIV------VGSNMDKIYIVMNYVEHDLKSLME 479
KEGFPIT+LREI + + +H N+V ++EI Y++ Y ++DL L+
Sbjct: 1101 KEGFPITALREIKILQQLEHENVVQLQEICHTQAGPYNRYKSTFYLIFEYCDYDLAGLLN 922
Query: 480 TMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYG 539
++ F + K LM QLL G+ ++H ILHRD+K +N+LL+ G+LK+ DFGL+R +
Sbjct: 921 NLRVKFSLADKKNLMSQLLNGLFYIHTKQILHRDIKAANILLTRDGVLKLADFGLSRPWV 742
Query: 540 SPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQIN 599
K T VVT WYR PELLLG +EY +DMW VGCI E+ ++KPL G SE Q++
Sbjct: 741 KS-KRLTNRVVTLWYRPPELLLGEREYGPEIDMWGVGCIMAEMWSRKPLMQGRSEQHQLS 565
Query: 600 KVFKELGTPSEKIWPGYSELPVVKKMTFSEHPYNNLRKRFGALLSD-QGFDLMNKFLTYF 658
+ G+ + ++WPG ++L + K+ + +++R LL + +G +L++ FL
Sbjct: 564 LITDLCGSLNAEVWPGVTKLELYGKLDLPQGKPRKVKERMLDLLKNKEGAELIDIFLRLD 385
Query: 659 PGRRISAEDGLKHEYFRETPLPIDPSM 685
PG+R++ ++ L H++F PLP PS+
Sbjct: 384 PGQRMNCDNALSHDFFWVDPLP-SPSL 307
>32000
Length = 644
Score = 170 bits (431), Expect = 2e-42, Method: Compositional matrix adjust.
Identities = 79/150 (52%), Positives = 106/150 (70%)
Frame = -1
Query: 527 LKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQK 586
+K+ DFGLAR +G P++ YT V+T WYRAPE+LLG + YS VD+WS+GCIF E++T++
Sbjct: 572 MKIADFGLARVFGLPVRTYTHEVITLWYRAPEILLGCRFYSVPVDIWSLGCIFVEMMTRR 393
Query: 587 PLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKMTFSEHPYNNLRKRFGALLSDQ 646
LFPG+SEIDQ+ ++F+ LGTP EK+WPG S+LP K TF + P NL LS
Sbjct: 392 ALFPGDSEIDQLYRIFRTLGTPDEKVWPGVSKLPDYKP-TFPKWPLKNLETVVS--LSKV 222
Query: 647 GFDLMNKFLTYFPGRRISAEDGLKHEYFRE 676
G DL+ + LTY P RRISA ++H YF +
Sbjct: 221 GLDLLKRMLTYNPNRRISARSAMRHPYFND 132
>01707
Length = 757
Score = 162 bits (411), Expect = 4e-40, Method: Compositional matrix adjust.
Identities = 81/221 (36%), Positives = 138/221 (62%)
Frame = +1
Query: 386 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 445
+E+++ + +I EG+YGVV++ ++K+T ++VA+K+ ++ ++REI + + +H
Sbjct: 61 MEKYEKIGKIGEGSYGVVFKCRNKETSQLVAIKKFVESEDDPLIKKIAMREIRMLKQLKH 240
Query: 446 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLH 505
PN+V R I V ++++V +YV+H L + ++ + VK ++ Q L V H
Sbjct: 241 PNLV--RLIEVFRRKKRLHLVFDYVDHTLLNELDRYPRGLPEPMVKRIIYQTLLAVNFCH 414
Query: 506 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKE 565
+HRD+K N+L++ G +K+ DFG AR P YT V T+WYRAPELL+G +
Sbjct: 415 QYNTIHRDVKPENILITRQGQVKLCDFGFARILTGPGDEYTDYVATRWYRAPELLVGDTQ 594
Query: 566 YSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELG 606
Y VD+W++GC+F ELLT + L+PG S++DQ++ + K LG
Sbjct: 595 YGPPVDVWAIGCVFAELLTGQALWPGRSDVDQLHLIRKTLG 717
>04138
Length = 800
Score = 151 bits (381), Expect = 1e-36, Method: Compositional matrix adjust.
Identities = 72/178 (40%), Positives = 111/178 (62%), Gaps = 6/178 (3%)
Frame = +1
Query: 503 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKA---YTPVVVTQWYRAPEL 559
++H N ILHRD+K +N+L++ G+LK+ DFGLAR + L+ YT VVT WYR PEL
Sbjct: 58 YIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRPPEL 237
Query: 560 LLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSEL 619
LLG + YSTA+D W GCI E+ T+ P+ G +E +Q+ + + G+ + ++WPG ++L
Sbjct: 238 LLGDRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQNQLTLITQLCGSITPEVWPGVTQL 417
Query: 620 PVVKKM--TFSEHPYNNLRKRFGALLSD-QGFDLMNKFLTYFPGRRISAEDGLKHEYF 674
+ ++ + N +R RF +L D G DL + L P +RISA++ L H++F
Sbjct: 418 SMYHQIKGALAAGRKNIIRDRFARILKDPYGLDLFERLLKMDPSQRISADEALNHDFF 591
>01966
Length = 1735
Score = 118 bits (296), Expect(2) = 3e-28, Method: Compositional matrix adjust.
Identities = 55/175 (31%), Positives = 107/175 (61%), Gaps = 2/175 (1%)
Frame = -1
Query: 406 AKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYI 465
+ + T +A+K++++ ++G P +++REI + + +H NIV + ++++ +++++
Sbjct: 1654 CRHRATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTNIVCLEDVIMED--ERLFL 1481
Query: 466 VMNYVEHDLKSLMETMKQPFLPGE--VKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSH 523
V ++ DLK ++ + + VK+ + Q++ G+ H I+HRDLK NLL++H
Sbjct: 1480 VFEFLSMDLKMYIDKFPEGVVLDRRLVKSYVFQIVTGINFCHQRRIVHRDLKPQNLLINH 1301
Query: 524 AGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCI 578
G +K+ DFG+AR + P++AYT VVT WYRAPE+L+G + + W+ G +
Sbjct: 1300 TGAIKIADFGMARTFALPVRAYTHEVVTLWYRAPEILMGPQ---STPPXWTCGAL 1145
Score = 25.4 bits (54), Expect(2) = 3e-28, Method: Composition-based stats.
Identities = 10/13 (76%), Positives = 12/13 (92%)
Frame = -2
Query: 392 LNRIEEGTYGVVY 404
L++I EGTYGVVY
Sbjct: 1695 LSKIGEGTYGVVY 1657
Score = 97.8 bits (242), Expect = 1e-20, Method: Compositional matrix adjust.
Identities = 54/138 (39%), Positives = 80/138 (57%)
Frame = -3
Query: 562 GAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPV 621
GA +YST VD+WS+G IF ++L + P+F G+SEIDQ+ K+F+ +GTP+E+ WP + +LP
Sbjct: 1187 GASKYSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKLPA 1008
Query: 622 VKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPI 681
M F L + L S G DL+ + L P +RIS + L+H YF +
Sbjct: 1007 FNGM-FPLWKEGKLSETLTDLDS-LGLDLIERTLKCDPAQRISCKKMLQHAYFLNVDTSV 834
Query: 682 DPSMFPTWPAKSEQQRVK 699
P P+ P +S R+K
Sbjct: 833 KPVDVPS-PEQS*STRLK 783
>23319
Length = 2235
Score = 103 bits (256), Expect = 3e-22, Method: Compositional matrix adjust.
Identities = 50/117 (42%), Positives = 72/117 (61%), Gaps = 1/117 (0%)
Frame = +3
Query: 563 AKEYSTAVDMWSVGCIFGELLTQ-KPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPV 621
AK YST++DMWS GCIF EL +PLFPGN + DQ+ ++FK LGTP+E WPG ++LP
Sbjct: 18 AKMYSTSIDMWSAGCIFAELANAGRPLFPGNDDDDQLKRIFKLLGTPTEDQWPGMTQLPN 197
Query: 622 VKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETP 678
+ F + ++ L+ +G DL+ L P R+SA++ L+H YF + P
Sbjct: 198 YR--MFPMYHVTTTWQQVVPKLNSKGRDLLQCLLVCCPSDRMSADEALQHPYFADLP 362
>00300
Length = 2318
Score = 95.1 bits (235), Expect = 1e-19, Method: Compositional matrix adjust.
Identities = 66/207 (31%), Positives = 108/207 (52%), Gaps = 13/207 (6%)
Frame = -1
Query: 393 NRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKA----QHPNI 448
N+I EG +G VY A + T E++ALK +K + + LRE+ +K QH N+
Sbjct: 1640 NKIGEGQFGKVYTAVNMSTGELMALKEMKFQPND----LQQLREMCDEIKIFEGIQHENL 1473
Query: 449 VTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNW 508
V + V + D++ + M Y D ++ E K ++ +++ V HLH+N
Sbjct: 1472 VKYYGVEV--HKDEMLMFMEYC--DTGTIEEAAKMGLPEYLIRRYTREIVLAVNHLHENS 1305
Query: 509 ILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTP-------VVVTQWYRAPELLL 561
I+HRD+K +N+ L+ G +K+GDFG + + LK++T +V T Y APE+
Sbjct: 1304 IVHRDIKGANIFLTSNGHVKLGDFGCSVK----LKSHTTMPGEFHNLVGTTAYMAPEVFT 1137
Query: 562 GAKE--YSTAVDMWSVGCIFGELLTQK 586
+ Y A D+WS+GC+ E+ T K
Sbjct: 1136 QNDQGGYGRAADIWSLGCVVIEMATGK 1056
>03294
Length = 1684
Score = 87.4 bits (215), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 49/130 (37%), Positives = 73/130 (56%)
Frame = -1
Query: 570 VDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKMTFSE 629
VD+WS+G IF ++L + P+F G+SEIDQ+ K+F+ +GTP+E+ WP + +LP M F
Sbjct: 1672 VDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKLPAFNGM-FPL 1496
Query: 630 HPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSMFPTW 689
L + L S G DL+ + L P +RIS + L+H YF + P P+
Sbjct: 1495 WKEGKLSETLTDLDS-LGLDLIERTLKCDPAQRISCKKMLQHAYFLNVDTSVKPVDVPS- 1322
Query: 690 PAKSEQQRVK 699
P S R+K
Sbjct: 1321 PEHS*STRLK 1292
>18921
Length = 697
Score = 85.5 bits (210), Expect = 7e-17, Method: Compositional matrix adjust.
Identities = 57/205 (27%), Positives = 109/205 (53%), Gaps = 6/205 (2%)
Frame = +2
Query: 389 FQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNI 448
F L ++ EG+YG V+++ K+T +++A+K++ ++ + + ++EI+ + + I
Sbjct: 35 FDILGKLGEGSYGSVFKSLHKETGQVLAIKQVPVDTDLQEI----IKEISIMQQCDSKYI 202
Query: 449 VTVREIVVGS---NMDKIYIVMNYV-EHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHL 504
V GS N D ++IVM Y + +M + + E+ T++ L+G+ +L
Sbjct: 203 VKYY----GSYFKNTD-LWIVMEYCGAGSVSDIMRLRNKTLVEREIATILYYTLKGLXYL 367
Query: 505 HDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELL--LG 562
H +HRD+K N+LL++ G K+ DFG+A + + V+ T ++ APE++ +G
Sbjct: 368 HSRRKIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTPYWMAPEVIQEIG 547
Query: 563 AKEYSTAVDMWSVGCIFGELLTQKP 587
Y D+WS+G E+ KP
Sbjct: 548 ---YDCVADIWSLGITALEMAEGKP 613
>06405
Length = 1965
Score = 83.2 bits (204), Expect = 4e-16, Method: Compositional matrix adjust.
Identities = 63/205 (30%), Positives = 102/205 (49%), Gaps = 8/205 (3%)
Frame = +1
Query: 388 EFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILK-AQHP 446
E +R+ G YG VY A K+ ++IVA+K LK ++ + E I+K +HP
Sbjct: 262 EIAMKHRLGGGQYGDVYEAMWKRYNKIVAVKTLK----EDTMALNDFLEEAAIMKEMKHP 429
Query: 447 NIVTVREIVVGSNMDKIYIVMNYVEHD--LKSLMETMKQPFLPGEVKTLMIQLLRGVKHL 504
N+V + + V + YIV ++ H L L + ++ P + + Q+ G+ +L
Sbjct: 430 NLVQL--LGVCTREPPFYIVTEFMPHGNLLDYLRSSTREENGPTALMYMATQIASGMAYL 603
Query: 505 HDNWILHRDLKTSNLLLSHAGILKVGDFGLAR-----EYGSPLKAYTPVVVTQWYRAPEL 559
+HRDL N L++ + ++KV DFGLAR Y + + A P+ +W APE
Sbjct: 604 ETKNFIHRDLAARNCLVADSNMVKVADFGLARLMKDDTYTAHIGAKFPI---KW-TAPE- 768
Query: 560 LLGAKEYSTAVDMWSVGCIFGELLT 584
L +ST D+W+ G + EL T
Sbjct: 769 GLAFNRFSTRSDIWAFGVLLWELAT 843
>13592
Length = 980
Score = 82.4 bits (202), Expect = 6e-16, Method: Compositional matrix adjust.
Identities = 80/295 (27%), Positives = 138/295 (46%), Gaps = 13/295 (4%)
Frame = +2
Query: 394 RIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVRE 453
+I +G +G VY A + T E++A+K + ++ + E+ + +H N+V
Sbjct: 5 KIGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETRALKNVAEELKILEGIKHKNLVRYYG 184
Query: 454 IVVGSNMDKIYIVMNYV-EHDLKSLMETMKQPFLPGEV-KTLMIQLLRGVKHLHDNWILH 511
I V + +++ I M E L+SL+E LP + + QLL GV LH + I+H
Sbjct: 185 IEV--HREELLIFMELCSEGTLESLVELTGG--LPEALSRRFTAQLLSGVAELHKHGIVH 352
Query: 512 RDLKTSNL-LLSHAGILKVGDFGLAREYGSPLKAYTPV-------VVTQWYRAPELL--L 561
RD+KT+N+ L+ + LK+GDFG A + ++A+T V V TQ Y APE+
Sbjct: 353 RDIKTANIFLVDGSNSLKLGDFGSAVK----IQAHTTVPGELQGYVGTQAYMAPEVFTKT 520
Query: 562 GAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGY-SELP 620
+ + D+WSVGC+ E+ + K + W + S
Sbjct: 521 NSDGHGRLADIWSVGCVVVEMASGK------------------------RPWAQFDSNFQ 628
Query: 621 VVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFR 675
++ K+ E P + LS +G D ++ L + P +R+SA + L+ + +
Sbjct: 629 IMFKVGMGEKP------QAPESLSQEGHDFIDHCLQHDPKQRLSAIELLEQNFCK 775
>12721
Length = 821
Score = 82.0 bits (201), Expect = 8e-16, Method: Compositional matrix adjust.
Identities = 53/196 (27%), Positives = 106/196 (54%)
Frame = +1
Query: 394 RIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVRE 453
+I EG+ G+V A + ++ A+K++ + K++ + E+ + HPNIV +
Sbjct: 109 KIGEGSTGIVCIATSRDGRQM-AVKKMDLRKQQRRELL--FNEVVVMRDYHHPNIVEMYN 279
Query: 454 IVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRD 513
+ + D++++VM ++E + + T + ++ T+ L+ + LH N ++HRD
Sbjct: 280 SYLVN--DELWVVMEFMEGGALTDIVTNNR-MDEVQIATVCRACLKALAFLHANGVIHRD 450
Query: 514 LKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMW 573
+K+ ++LLSH G +K+ DFG + L+ +V T ++ APE ++ Y VD+W
Sbjct: 451 IKSDSILLSHDGKVKLXDFGFCAQVTQDLQKRKSLVGTPYWMAPE-VISRLPYGPEVDIW 627
Query: 574 SVGCIFGELLTQKPLF 589
S+G + E++ +P F
Sbjct: 628 SLGIMVMEMIDAEPPF 675
>01718
Length = 959
Score = 79.7 bits (195), Expect = 4e-15, Method: Compositional matrix adjust.
Identities = 60/218 (27%), Positives = 107/218 (49%), Gaps = 6/218 (2%)
Frame = +3
Query: 379 ALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREIN 438
A+ +++F C +I G + V++ + T +++ALK M + LRE+
Sbjct: 126 AVSALTRLDDFIC-EKIGAGFFSEVFKVTHRITGQVMALKMNTMTSNRHNM----LREVQ 290
Query: 439 TILKAQHPNIVTVREIVVGSNMDKIYIVMNYV-EHDLKSLMETMKQPFLPGEVKTLMIQL 497
+ + QH NI+ + V +++ + Y+ +L+ L+E + + L + L
Sbjct: 291 LLNRLQHANILRFMGVCVHEG--QLHALTEYIPSGNLEQLLEKKDEELPWTQRIQLTLGL 464
Query: 498 LRGVKHLHDNWILHRDLKTSNLLL----SHAGILKVGDFGLAREYGSPL-KAYTPVVVTQ 552
RG+ +LH +HRDL + N+L+ +H + DFGLA + PL K P V +
Sbjct: 465 ARGLDYLHSTRFIHRDLTSKNILIRREDNHGYHAVIADFGLATKIPDPLDKEKLPTVGSP 644
Query: 553 WYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFP 590
++ APE+L G Y+ D++SVG I E+ + P P
Sbjct: 645 YWMAPEVLNG-HFYNERADLFSVGIIMCEITARIPADP 755
>09606
Length = 1300
Score = 77.4 bits (189), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 82/314 (26%), Positives = 134/314 (42%), Gaps = 24/314 (7%)
Frame = -3
Query: 386 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 445
+E F + +G + ++Y+ + K T VA+ + EK K ++R + I H
Sbjct: 1118 MENFVLYEELGKGEHSIIYKGRRKGTINFVAIHCI--EKCKRPEVTNTVRMTHDI---SH 954
Query: 446 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPF-LP-GEVKTLMIQLLRGVKH 503
PN+V E SN +++V+ SL + + Q LP ++ I L+ G+ +
Sbjct: 953 PNVVQFHEWYETSN--HLWLVVELCTGG--SLADILAQDHHLPETSIRDFGIHLVTGLHY 786
Query: 504 LHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAY------------------ 545
+H IL DL+ S +LL +G+LK DFGL++ G L+
Sbjct: 785 IHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQWNIQSAEE 606
Query: 546 ----TPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKV 601
P + Y APE+ GA E S D+W++GC+F E+ + P F G + +KV
Sbjct: 605 MMKQVPTSGSPTYMAPEVFQGA-EPSIMSDLWALGCVFYEMFSGHPPFLGETYDITKDKV 429
Query: 602 FKELGTPSEKIWPGYSELPVVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGR 661
K +P LP VK S P S + +L+ L R
Sbjct: 428 LN-------KEFP----LPKVKGSRLSAKP------------SPEFLNLLESLLQKDSTR 318
Query: 662 RISAEDGLKHEYFR 675
R+S +KH +++
Sbjct: 317 RLSWASLVKHAFWQ 276
>03508
Length = 1463
Score = 76.6 bits (187), Expect = 4e-14, Method: Compositional matrix adjust.
Identities = 39/122 (31%), Positives = 72/122 (59%), Gaps = 2/122 (1%)
Frame = +1
Query: 471 EHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGI-LKV 529
EH + + + Q F +++ + +L++ + H I+HRD+K N+++ H L++
Sbjct: 820 EHVNNTDFKQLYQTFTDYDIRFYLYELMKALDFCHSMGIMHRDVKPHNVMIDHENKKLRL 999
Query: 530 GDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQK-PL 588
D+GLA E+ P Y V +++++ PELLL + Y ++DMWS+GC+F ++ +K PL
Sbjct: 1000IDWGLA-EFYHPGMEYNVRVASRYFKGPELLLDYQMYDYSLDMWSLGCMFASMIFRKEPL 1176
Query: 589 FP 590
P
Sbjct: 1177LP 1182
Score = 35.0 bits (79), Expect = 0.099, Method: Compositional matrix adjust.
Identities = 27/114 (23%), Positives = 51/114 (44%), Gaps = 12/114 (10%)
Frame = +2
Query: 573 WSVG----CIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKMTFS 628
W+ G C+ + P F G+ DQ+ ++ K LGT + ++ + + F+
Sbjct: 1118 WTCGVWAACLPA*SSGKSPFFHGHDNYDQLVRIAKVLGT--DDLYGYIEKYQIDLDPRFN 1291
Query: 629 EHPYNNLRKRF--------GALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYF 674
+ + RKR+ L+S + D ++K L Y R++A + + H YF
Sbjct: 1292 DILGRHSRKRWERFVHSENQHLISPEALDFLDKLLRYDHNERLTAREAMDHPYF 1453
>20559
Length = 430
Score = 65.9 bits (159), Expect(2) = 1e-13, Method: Compositional matrix adjust.
Identities = 31/82 (37%), Positives = 58/82 (70%)
Frame = -2
Query: 374 PKYLPALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITS 433
P +L + +++++ L +I EGTYG V++AK+++T EIVALKR++++ + EG P ++
Sbjct: 414 PTHLHSF*LKHKMQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSA 235
Query: 434 LREINTILKAQHPNIVTVREIV 455
LREI + + +H NIV + +++
Sbjct: 234 LREICLLKELKHRNIVRLHDVL 169
Score = 29.3 bits (64), Expect(2) = 1e-13, Method: Composition-based stats.
Identities = 14/36 (38%), Positives = 19/36 (52%)
Frame = -3
Query: 469 YVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHL 504
Y + DLK +T P VK+ + QLLRG+ L
Sbjct: 134 YCDQDLKKYFDTCNGEIDPDTVKSFLHQLLRGLGFL 27
>12453
Length = 680
Score = 73.9 bits (180), Expect = 2e-13, Method: Composition-based stats.
Identities = 41/100 (41%), Positives = 55/100 (55%)
Frame = +3
Query: 575 VGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKMTFSEHPYNN 634
VGCIF E+ +PLFPG++ D+++ +FK LGTP+E P S P + +
Sbjct: 6 VGCIFYEMACGRPLFPGSTVEDELHLIFKTLGTPTEDSLPSISRNPDFLALNLPHYQGEA 185
Query: 635 LRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYF 674
L L SD G DL+ KFL Y R+SA D LKH +F
Sbjct: 186 LITIAPRLDSD-GLDLLAKFLKYNAKIRVSAADSLKHSFF 302
>14420
Length = 528
Score = 73.2 bits (178), Expect = 3e-13, Method: Compositional matrix adjust.
Identities = 44/156 (28%), Positives = 90/156 (57%), Gaps = 2/156 (1%)
Frame = +2
Query: 434 LREINTILKAQHPNIVT-VREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLP-GEVK 491
+ EI + + Q+PNIV + +VG +++++VM ++ SL + + + + G++
Sbjct: 44 INEILVMRENQNPNIVNYLDSYLVG---EELWVVMEFLAGG--SLTDVVTETCMDEGQIA 208
Query: 492 TLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVT 551
+ + L+ ++ LH+N ++HRD+K+ N+LL G +K+ DFG + + +V T
Sbjct: 209 AVCRECLQALEFLHENQVIHRDIKSDNILLGMDGSVKLTDFGFCAQLSPEQSKRSTMVGT 388
Query: 552 QWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKP 587
++ APE ++ K+Y VD+WS+G + E++ +P
Sbjct: 389 PYWMAPE-VVTRKQYGPTVDIWSLGVMCIEMIEGEP 493
>15910
Length = 1361
Score = 70.9 bits (172), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 49/125 (39%), Positives = 67/125 (53%), Gaps = 3/125 (2%)
Frame = +2
Query: 497 LLRGVKHLHDNWILHRDLKTSNLL---LSHAGILKVGDFGLAREYGSPLKAYTPVVVTQW 553
+L GV+++H N ++HRDLK NLL ++ LK+ DFGL+R P + V T
Sbjct: 491 ILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLADFGLSR-IIEPEVQMSTVCGTPG 667
Query: 554 YRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIW 613
Y APE+L G K Y+ +VDMWSVG I LL F +E + K+ K E+ W
Sbjct: 668 YCAPEVLKGDK-YTPSVDMWSVGVIAYILLCGYEPFFAENEFEMYRKIIKGEYKFDEEYW 844
Query: 614 PGYSE 618
SE
Sbjct: 845 SEISE 859
>26560
Length = 398
Score = 68.2 bits (165), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 37/119 (31%), Positives = 66/119 (55%), Gaps = 4/119 (3%)
Frame = -1
Query: 485 FLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKA 544
F EV+ +++ G++H+H ++++RDLK +N+LL G +++ D GLA ++ K
Sbjct: 365 FTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGLACDFSK--KR 192
Query: 545 YTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLF----PGNSEIDQIN 599
V T Y APE+L+ + Y ++ D +S GC+ +LL F G + ID++
Sbjct: 191 PHASVGTHGYMAPEVLMKGQSYDSSADWFSFGCMLYKLLKGHSPFRQHNQGQARIDRMT 15
>19761
Length = 473
Score = 65.5 bits (158), Expect = 8e-11, Method: Compositional matrix adjust.
Identities = 36/104 (34%), Positives = 60/104 (57%)
Frame = -3
Query: 503 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLG 562
H H ILHRDLK N+ ++ G +++GD GLAR+ P T V T Y +PE +L
Sbjct: 372 HTHTPVILHRDLKPQNIYVTEKGDVRLGDLGLARKLTGPADFATSQVGTIMYLSPE-ILS 196
Query: 563 AKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELG 606
+ Y++ D+WS+GC+F ++ +K G+ E+ + + + +G
Sbjct: 195 QQPYNSKSDIWSLGCVFYDITGKK----GSDEMGVMFLLVQVMG 76
>18484
Length = 635
Score = 65.5 bits (158), Expect = 8e-11, Method: Compositional matrix adjust.
Identities = 35/99 (35%), Positives = 55/99 (55%)
Frame = +1
Query: 496 QLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYR 555
++ G+ LHD I++RDLK N++L G +K+ DFG+ +E + T Y
Sbjct: 67 EIAVGLFFLHDQGIIYRDLKLDNVMLDSEGHIKIADFGMCKEGMTGDATTRTFCGTPDYI 246
Query: 556 APELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSE 594
APE++L + YS +VD W+ G + E+L +P F G E
Sbjct: 247 APEIVL-YQPYSKSVDWWAYGVLLFEMLAGQPPFDGEDE 360
>21578
Length = 524
Score = 63.9 bits (154), Expect = 2e-10, Method: Composition-based stats.
Identities = 26/33 (78%), Positives = 31/33 (93%)
Frame = +2
Query: 369 LKQELPKYLPALQGCRSVEEFQCLNRIEEGTYG 401
LK++LP YLPA+QGCR+VEEF C+NRIEEGTYG
Sbjct: 425 LKEDLPVYLPAIQGCRNVEEFHCMNRIEEGTYG 523
>27546
Length = 426
Score = 62.8 bits (151), Expect = 4e-10, Method: Composition-based stats.
Identities = 38/113 (33%), Positives = 60/113 (53%), Gaps = 2/113 (1%)
Frame = -1
Query: 426 KEGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQ-- 483
K+ FP RE+ + + HPNI+ + I+ KI+I M Y E ++ +K+
Sbjct: 348 KKFFP----RELEILTRLDHPNIIQIHSIL--QRGPKIFIFMRYAEKG--DMLSHIKKTG 193
Query: 484 PFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAR 536
P + K Q+ + +++LH + I HRDLK N+LLS +K+ DFG AR
Sbjct: 192 PIDEAQTKVWFFQMAKALQYLHSHDIAHRDLKCENILLSKRLNVKIADFGFAR 34
>14116
Length = 1017
Score = 62.0 bits (149), Expect = 9e-10, Method: Compositional matrix adjust.
Identities = 61/205 (29%), Positives = 99/205 (48%), Gaps = 14/205 (6%)
Frame = -1
Query: 395 IEEGTYGVVYRA----KDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVT 450
I +G +G V R ++K D +VA+K L +E + L+E + H N++T
Sbjct: 612 IGKGNFGCVKRGFLTLPEQKGDILVAVKTLHNNNPREIELQSFLQEALIMKDFHHSNVLT 433
Query: 451 VREIVVGSNMDKI-YIVMNYVEHD--LKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDN 507
+ I + N+D + +V+ +++H L + + QP + ++ + + RG+ +L
Sbjct: 432 LIGICL--NLDDMPLVVLPFMKHGDLLTYIRDDQHQPTIK-DLIMYGVDIARGMDYLAGL 262
Query: 508 WILHRDLKTSNLLLSHAGILKVGDFGLAR-----EYGSP--LKAYTPVVVTQWYRAPELL 560
+HRDL N +L +KV DFGLAR EY S KA PV +W L
Sbjct: 261 KFVHRDLAARNCMLDEDFHVKVADFGLARDIYEKEYYSSENKKAKLPV---KWMALESLE 91
Query: 561 LGAKEYSTAVDMWSVGCIFGELLTQ 585
G Y + D+WS G + ELLT+
Sbjct: 90 KG--NYDSKTDVWSYGVVLWELLTR 22
>03240
Length = 1683
Score = 61.6 bits (148), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 62/262 (23%), Positives = 105/262 (40%), Gaps = 48/262 (18%)
Frame = -3
Query: 389 FQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNI 448
F+ + + G +G V + T + A+K L+ + + ++ IL A+ N
Sbjct: 1285 FEKIKTLGVGAFGEVSLCRKNDTGMLYAMKTLRKSDVLKRNQVAHVKAERDIL-AEADNE 1109
Query: 449 VTVREIVVGSNMDKIYIVMNYVEH-DLKSL---METMKQPFLPGEVKTLMIQLLRGVKHL 504
V+ + + +Y VM+YV DL L ME + +P + + +L++ ++ +
Sbjct: 1108 WVVKLYYSFQDHNYLYFVMDYVPGGDLMGLLIRMEILDEPL----ARFYVAELVQAIESV 941
Query: 505 HDNWILHRDLKTSNLLLSHAGILKVGDFGL-------------------AREYGSPLKAY 545
H +HRD+K N+L+ G +K+ DFGL AR+ +K
Sbjct: 940 HRMGFIHRDIKPDNILIDRNGHIKLTDFGLCTGFRWTHNSKYYQRDGTHARQDSMEVKCQ 761
Query: 546 T-------------------------PVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFG 580
+V T Y APE+L Y++ D WSVG I
Sbjct: 760 LDEQCQCEILKPLERRRKREQRCLAHSLVGTPNYIAPEVLSRLGGYTSVCDWWSVGVILF 581
Query: 581 ELLTQKPLFPGNSEIDQINKVF 602
E+L P F N+ + KV
Sbjct: 580 EMLVGHPPFYANTPAETQYKVI 515
>30755
Length = 1137
Score = 61.2 bits (147), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 35/94 (37%), Positives = 51/94 (54%), Gaps = 3/94 (3%)
Frame = +2
Query: 496 QLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLARE---YGSPLKAYTPVVVTQ 552
+++ + +LH I++RDLK NLLL G +KV DFGL +E YG K + T
Sbjct: 56 EIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCKEDITYGRTTKTFCG---TP 226
Query: 553 WYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQK 586
Y APE +L +Y AVD W G + E++ +
Sbjct: 227 EYLAPE-VLDDNDYGRAVDWWGTGVVMYEMICGR 325
>13212
Length = 1067
Score = 61.2 bits (147), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 46/206 (22%), Positives = 93/206 (45%), Gaps = 4/206 (1%)
Frame = -1
Query: 474 LKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFG 533
L S+M +++P ++ + ++ + LH + ++HRD+K N+LL+ G +K+ DFG
Sbjct: 1022 LDSIMVDLEKPMTEAQICYVCHEMCMALDFLHRHHVIHRDIKAGNVLLTIDGEVKLADFG 843
Query: 534 LAREYGSPLKAYTPVVVTQWYRAPELLLGA----KEYSTAVDMWSVGCIFGELLTQKPLF 589
++ + + + T ++ APE++L Y D+WS+G E
Sbjct: 842 VSAKNTQTQQKRDTFIGTPYWMAPEVVLCETLKDTPYDFKADIWSLGVTLIE-------- 687
Query: 590 PGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKMTFSEHPYNNLRKRFGALLSDQGFD 649
F ++ P++++ P + V+ K+ S+ P K++ L D
Sbjct: 686 ------------FAQIEPPNKEMHP----MRVLIKIHKSDPPTLEKPKKWTKLFK----D 567
Query: 650 LMNKFLTYFPGRRISAEDGLKHEYFR 675
+ K L P R +A + L+H + +
Sbjct: 566 FIAKCLVKDPNLRPTAAELLEHPFMK 489
>28638
Length = 1458
Score = 60.8 bits (146), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 33/81 (40%), Positives = 51/81 (62%), Gaps = 2/81 (2%)
Frame = -1
Query: 509 ILHRDLKTSNLLLSHA--GILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEY 566
I+H DLK N+LL + +K+ DFG + + G + Y + +++YR+PE+LLG Y
Sbjct: 768 IIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQY---IQSRFYRSPEVLLGVP-Y 601
Query: 567 STAVDMWSVGCIFGELLTQKP 587
A+DMWS+GCI E+ T +P
Sbjct: 600 DLAIDMWSLGCILVEMHTGEP 538
Score = 30.0 bits (66), Expect = 3.9, Method: Compositional matrix adjust.
Identities = 15/52 (28%), Positives = 22/52 (42%), Gaps = 5/52 (9%)
Frame = -2
Query: 566 YSTAVDMWSVGC-----IFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKI 612
Y W + C + PLF G++E DQ+ K+ + LG P I
Sbjct: 617 YXXCPMTWPLTCGXWAVYWWRCTXGNPLFAGSNEFDQMMKIVEVLGVPPRHI 462
>13066
Length = 551
Score = 60.5 bits (145), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 52/188 (27%), Positives = 88/188 (46%), Gaps = 6/188 (3%)
Frame = +3
Query: 395 IEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREI 454
+ GT+ Y K +I+ ++ ++ ++ FP RE++ + K HP I+ + I
Sbjct: 15 VVHGTFNDGYGRNIKLACKIIDKEKAPVDFVEKFFP----RELDLLTKLDHPYIIQIHSI 182
Query: 455 VVGSNMDKIYIVMNYVEH-DLKSLMETMKQPFLP-GEVKTLMIQLLRGVKHLHDNWILHR 512
+ K +I M + E DL + ++ + F+ + K Q+ + +LH + HR
Sbjct: 183 L--QRXPKNFIFMRFAERGDLLTYIQEVG--FVKEKQAKIWFYQMTTALNYLHSYDVAHR 350
Query: 513 DLKTSNLLLSHAGILKVGDFGLA----REYGSPLKAYTPVVVTQWYRAPELLLGAKEYST 568
DLK N+LLS +K+ DFG A E G + T + Y APE++ GA
Sbjct: 351 DLKCENILLSSHFNVKLADFGFACACITESGEKYMSRT-YCGSAAYAAPEIVYGAPYAPK 527
Query: 569 AVDMWSVG 576
D WS+G
Sbjct: 528 VADAWSLG 551
>26909
Length = 394
Score = 60.1 bits (144), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 38/119 (31%), Positives = 57/119 (47%), Gaps = 16/119 (13%)
Frame = +2
Query: 578 IFGELLTQKPLFPGNSEI---------DQINKVFKELGTPSEKIWPGYSELPVVKKMT-- 626
IF ELLT +P+F E DQ++++F +G P EK W +P +++T
Sbjct: 2 IFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFPQEKDWEDIRRMPEHQQLTKD 181
Query: 627 FSEHPYNNLR-----KRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLP 680
F Y N ++ + F L+ K LT P +RI++E +K YF E PLP
Sbjct: 182 FKRSSYVNCNLMKYMEKHKVKADSKAFHLLQKLLTMDPVKRITSEQAMKDPYFLEEPLP 358
>19094
Length = 898
Score = 58.9 bits (141), Expect = 8e-09, Method: Compositional matrix adjust.
Identities = 31/105 (29%), Positives = 58/105 (55%), Gaps = 2/105 (1%)
Frame = +1
Query: 474 LKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFG 533
+ +M + + E+ T++ L+G+ +LH +HRD+K N+LL++ G K+ DFG
Sbjct: 16 VSDIMRLRNKTLVEREIATILYYTLKGL*YLHSRRKIHRDIKAGNILLNNEGHAKLADFG 195
Query: 534 LAREYGSPLKAYTPVVVTQWYRAPELL--LGAKEYSTAVDMWSVG 576
+A + + V+ T ++ APE++ +G Y D+WS+G
Sbjct: 196 VAGQLTDTMAKRNTVIGTPYWMAPEVIQEIG---YDCVADIWSLG 321
>21808
Length = 1011
Score = 58.2 bits (139), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 56/201 (27%), Positives = 96/201 (47%), Gaps = 14/201 (6%)
Frame = +1
Query: 415 VALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDL 474
VA+K LK P L E + K +HP ++ + V + D I+I+ +++
Sbjct: 28 VAIKTLKSGTMD---PKDFLAEAQIMKKLRHPKLIQL--YAVCTQDDPIFIITELMKNG- 189
Query: 475 KSLMETMKQPFLPGEVKTLMI--------QLLRGVKHLHDNWILHRDLKTSNLLLSHAGI 526
SL+E FL G+ + L + Q+ G+ +L +HRDL N+L+S
Sbjct: 190 -SLLE-----FLQGKGRVLKLPALIDIGAQIACGMAYLESQNYIHRDLAARNILVSDNNT 351
Query: 527 LKVGDFGLAR-----EYGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGE 581
+K+ DFGLAR EY + + A P+ +W APE ++ D+WS G + E
Sbjct: 352 VKIADFGLARVIKEDEYEARVGARFPI---KW-TAPE-AANYNRFTIKSDVWSFGILLTE 516
Query: 582 LLTQKPL-FPGNSEIDQINKV 601
+T + +PG + + +++V
Sbjct: 517 TVTYGRVPYPGMTNAEVLHQV 579
>11185
Length = 473
Score = 56.6 bits (135), Expect = 4e-08, Method: Compositional matrix adjust.
Identities = 35/117 (29%), Positives = 56/117 (47%), Gaps = 22/117 (18%)
Frame = +1
Query: 490 VKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAY---- 545
++ I L+ G+ ++H IL DL+ S +LL +G+LK DFGL++ G L+
Sbjct: 7 IRDFGIHLVTGLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKF 186
Query: 546 ------------------TPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLT 584
P + Y APE+ GA E S D+W++GC+F E+ +
Sbjct: 187 AEAGDQWNIQSAEEMMKQVPTSGSPTYMAPEVFQGA-EPSIMSDLWALGCVFYEMFS 354
>19301
Length = 712
Score = 55.8 bits (133), Expect = 6e-08, Method: Compositional matrix adjust.
Identities = 43/149 (28%), Positives = 75/149 (50%), Gaps = 2/149 (1%)
Frame = +2
Query: 387 EEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHP 446
E L + G G V+ K E VA+K+++ KE + I +LR++N HP
Sbjct: 305 ESITDLEWLGSGAQGAVFLGK--LCAEEVAVKKVRDIKETD---IRNLRKLN------HP 451
Query: 447 NIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMK--QPFLPGEVKTLMIQLLRGVKHL 504
NI++ + + + I+M Y + L E ++ + P V Q+ G+ +L
Sbjct: 452 NIISFKGVC--TQAPCYCIIMEYCPY--GQLYEVLRDGKEIPPALVLDWSKQIASGMNYL 619
Query: 505 HDNWILHRDLKTSNLLLSHAGILKVGDFG 533
H + I+HRDLK+ N+L++ ++K+ DFG
Sbjct: 620 HSHKIIHRDLKSPNVLVAKNDVVKISDFG 706
>27405
Length = 532
Score = 55.8 bits (133), Expect = 6e-08, Method: Compositional matrix adjust.
Identities = 28/89 (31%), Positives = 52/89 (58%)
Frame = -3
Query: 485 FLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKA 544
F EV+ +++ G++H+H ++++RDLK +N+LL G +++ D GLA ++ K
Sbjct: 263 FTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGLACDFSK--KK 90
Query: 545 YTPVVVTQWYRAPELLLGAKEYSTAVDMW 573
V T Y APE+L+ + Y ++ D +
Sbjct: 89 PHASVGTHGYMAPEVLMKGQAYDSSADWF 3
>07940
Length = 1336
Score = 55.8 bits (133), Expect = 7e-08, Method: Compositional matrix adjust.
Identities = 35/112 (31%), Positives = 56/112 (50%), Gaps = 6/112 (5%)
Frame = -3
Query: 479 ETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLARE- 537
+ M + P ++ + Q+ RG+++L +HRDL N+L++ +LK+ DFGL R
Sbjct: 374 QDMLKMLTPKDLISYAYQVARGMEYLASKQCIHRDLAARNVLVAEEYVLKIADFGLTRNL 195
Query: 538 -----YGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLT 584
Y PV +W APE L K Y++ D+WS G + E+ T
Sbjct: 194 QQFDYYRKTTDGRLPV---KW-MAPEALFDRK-YTSKSDVWSYGVLLWEIFT 54
>18287
Length = 678
Score = 55.5 bits (132), Expect = 8e-08, Method: Composition-based stats.
Identities = 35/119 (29%), Positives = 53/119 (44%), Gaps = 8/119 (6%)
Frame = -3
Query: 566 YSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKM 625
Y ++D+WSVGCIF ELL+++ LF + Q++ + +GTP + E
Sbjct: 673 YDYSIDIWSVGCIFAELLSRRILFQAQGPVQQLDMIINLVGTPRPEDMERACE------- 515
Query: 626 TFSEHPYNNLRKRFGALL--------SDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 676
H N +R L + + L+ + L P RISAE+ L H Y E
Sbjct: 514 GARNHILNQPFRRQNLLTLYNLSPHATHEAVRLLTRMLILNPKNRISAEEALSHPYLDE 338
>26711
Length = 405
Score = 55.5 bits (132), Expect = 8e-08, Method: Composition-based stats.
Identities = 39/111 (35%), Positives = 61/111 (54%), Gaps = 6/111 (5%)
Frame = -2
Query: 496 QLLRGVKHLHDNWILHRDLKTSNLLLSHAGI--LKVGDFGLAREYGSPLKAY----TPVV 549
Q+L ++H+H ++H DLK SNLLLS + +++ DFGLAR+ P + + TP
Sbjct: 392 QVLDILQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARKLYPPQETFLNHGTP-- 219
Query: 550 VTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINK 600
+ +PE L K STA D+W VG + LL+ + F +S + + K
Sbjct: 218 ---GFTSPE-ALDVKPISTASDVWGVGVLAYILLSGQSPFQADSATESLKK 78
>24241
Length = 413
Score = 55.1 bits (131), Expect = 9e-08, Method: Compositional matrix adjust.
Identities = 25/84 (29%), Positives = 54/84 (64%)
Frame = -2
Query: 392 LNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTV 451
L++I EGTYGVVY+ + + T +A+K++++ ++G P +++REI + + +H +
Sbjct: 328 LSKIGEGTYGVVYKCRHRATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTQXLVC 149
Query: 452 REIVVGSNMDKIYIVMNYVEHDLK 475
E V+ + +++++V ++ DLK
Sbjct: 148 LEDVIMED-ERLFLVFEFLSMDLK 80
>28157
Length = 400
Score = 55.1 bits (131), Expect = 1e-07, Method: Composition-based stats.
Identities = 44/129 (34%), Positives = 67/129 (51%), Gaps = 8/129 (6%)
Frame = +3
Query: 415 VALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSNMDK-IYIVMNYVEHD 473
VA+KR++ E+EK+ F ++E+ + + HPNIV + G+ D + +VM Y E
Sbjct: 9 VAVKRIESEQEKKSF----MQELKQLSRVSHPNIVCL----YGACRDHPVCLVMEYAEGG 164
Query: 474 --LKSLMETMKQP-FLPGEVKTLMIQLLRGVKHLHD---NWILHRDLKTSNLLLSHAGI- 526
L + QP + ++Q GV++LH ++HRDLK NLLL G
Sbjct: 165 SLYNVLHGSGPQPQYTAAHAMNWLLQCALGVEYLHGMKPKALIHRDLKPPNLLLIQCGTK 344
Query: 527 LKVGDFGLA 535
LK+ DFG A
Sbjct: 345 LKICDFGTA 371
>31489
Length = 329
Score = 54.7 bits (130), Expect = 1e-07, Method: Composition-based stats.
Identities = 28/81 (34%), Positives = 50/81 (61%), Gaps = 4/81 (4%)
Frame = +3
Query: 444 QHPNIVTVREIVVGSN----MDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLR 499
+H NI+++REI+ + I++V + +E DL ++ + QP ++ + Q+LR
Sbjct: 24 KHDNIISIREILKPKDSYHDFKDIHVVFDLMESDLHRIIYS-DQPLTEEHIRYFLYQILR 200
Query: 500 GVKHLHDNWILHRDLKTSNLL 520
G+K++H ++HRDLK SNLL
Sbjct: 201 GLKYIHSANVVHRDLKPSNLL 263
>12672
Length = 773
Score = 53.5 bits (127), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 31/89 (34%), Positives = 50/89 (56%), Gaps = 4/89 (4%)
Frame = +3
Query: 500 GVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREY----GSPLKAYTPVVVTQWYR 555
G+++L+DN +HRD+KT+N+LL KVGDF G ++ + V+ T Y
Sbjct: 27 GIQYLNDNGHVHRDIKTANILLDSEYTAKVGDFATVVSAPSGEGKTVQNASVVIGTAAYL 206
Query: 556 APELLLGAKEYSTAVDMWSVGCIFGELLT 584
APE + + ST +D +S G + E++T
Sbjct: 207 APEAI--HFDVSTKLDSYSFGVVLLEVIT 287
>17253
Length = 483
Score = 53.1 bits (126), Expect = 4e-07, Method: Composition-based stats.
Identities = 44/140 (31%), Positives = 67/140 (47%), Gaps = 14/140 (10%)
Frame = -1
Query: 423 EKEKEGFPITSLREINTILK-AQHPNIVTVREIVVGSNMDKIYIVMNYVEH-DLKSLMET 480
+ EK F LRE++ + K +HPN+V+ S D I+M + H DL S +
Sbjct: 426 DAEKSEF----LRELSIMRKLPRHPNVVSFMGCCTMS--DPALILMEFCCHGDLLSFLRK 265
Query: 481 MKQP----FLPGEVKTLM--------IQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILK 528
++P FL L + + RG+ H+ +N I+HRD+ N+L+S + K
Sbjct: 264 -RRPDRTVFLTSTANDLTARDFFSFALHVARGMAHVANNKIVHRDVAARNVLISERNVCK 88
Query: 529 VGDFGLAREYGSPLKAYTPV 548
V DFGL+R G Y V
Sbjct: 87 VSDFGLSRRVGDQNDVYEIV 28
>04852
Length = 1462
Score = 52.8 bits (125), Expect = 5e-07, Method: Compositional matrix adjust.
Identities = 30/90 (33%), Positives = 48/90 (53%)
Frame = +1
Query: 495 IQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWY 554
Q+ RG++ L +HRDL N+L++ +LK+ DFGL+R K + +W
Sbjct: 346 FQIARGMEFLASRKCIHRDLAARNVLVTEEHVLKIADFGLSRTGDYYKKRSGGRLPVKWM 525
Query: 555 RAPELLLGAKEYSTAVDMWSVGCIFGELLT 584
APE L + Y+T D+WS G + E+ +
Sbjct: 526 -APEALFDMR-YTTKSDVWSFGVVLWEIFS 609
>00715
Length = 1788
Score = 52.0 bits (123), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 48/177 (27%), Positives = 84/177 (47%), Gaps = 29/177 (16%)
Frame = +1
Query: 444 QHPNIVTVREIVVGSNM-----DKIYIVMNYV-EHDLKSLMETMKQPFLPGEVKTLMIQL 497
+H N+V++ +G+ D ++ M YV +L++++ +Q +L +Q+
Sbjct: 100 RHVNVVSI----LGATSLHRFEDGAWLAMEYVGPLNLQTILNDHQQDIDSSMRLSLALQM 267
Query: 498 LRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREY---------------GSPL 542
RG+ +LH I+H DLK +N LL+ L++ DFG + G+ L
Sbjct: 268 ARGLHYLHSINIVHLDLKPANCLLTRDLKLRIADFGCCHQLTPTGLDMGEREGGMAGNEL 447
Query: 543 KAYTPV--------VVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPG 591
+ TPV T YRAPELL G + S D++S+G ++ T++ + G
Sbjct: 448 E-LTPVQGAWKNELAGTLAYRAPELLKGLQP-SVRSDVYSLGITLWQMCTRQGPYEG 612
>18401
Length = 463
Score = 51.6 bits (122), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 39/144 (27%), Positives = 66/144 (45%), Gaps = 14/144 (9%)
Frame = -3
Query: 545 YTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKE 604
++ +V T+ YRAPE++L +S D+WSVGCI EL T LF + + + + +
Sbjct: 461 HSTIVSTRHYRAPEVILELG-WSHPCDVWSVGCIMFELYTGYTLFQTHDNKEHLAMMERI 285
Query: 605 LGTPSEKI--------WPGYSELPVVKKMTFSEHPYNNLRKRFGALLS------DQGFDL 650
LG+ ++ + + L V ++ + + + N + + Q FDL
Sbjct: 284 LGSLPYRMAKKTKKQKYFHHGRLDVPERSSMARYVRENTKPLLRYVKDRENKDHQQLFDL 105
Query: 651 MNKFLTYFPGRRISAEDGLKHEYF 674
M K L Y R S L+H +F
Sbjct: 104 MKKLLAYEASSRYSLLQALQHPFF 33
>21079
Length = 878
Score = 50.8 bits (120), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 34/91 (37%), Positives = 50/91 (54%), Gaps = 2/91 (2%)
Frame = +1
Query: 496 QLLRGVKHLHDNWILHRDLKTSNLLL--SHAGILKVGDFGLAREYGSPLKAYTPVVVTQW 553
Q+ GV ++H ILH DLK N+L ++ +K+ DFGLAR Y P + + T
Sbjct: 151 QICSGVGYMHTQSILHLDLKPENVLCVSDNSNQIKIIDFGLARFY-KPGDSLQVLFGTPE 327
Query: 554 YRAPELLLGAKEYSTAVDMWSVGCIFGELLT 584
+ APE ++ E + DMWS+G I LL+
Sbjct: 328 FIAPE-VVNYDEINFTTDMWSIGVICYILLS 417
>16003
Length = 926
Score = 50.8 bits (120), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 35/99 (35%), Positives = 51/99 (51%)
Frame = -1
Query: 582 LLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKMTFSEHPYNNLRKRFGA 641
LL + P PG++++DQ+ K+F LGTP+E WP + LP + F L++ F A
Sbjct: 926 LLIRLPFLPGDTDLDQLGKIFNMLGTPTETEWPAVTSLP--DYIQFKHCQKQPLKEIFTA 753
Query: 642 LLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLP 680
D +L++K L P R +A LK YF P P
Sbjct: 752 -AGDDLLELLDKLLAMNPLHRCTATQALKMPYFSNKPYP 639
>00392
Length = 668
Score = 50.1 bits (118), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 46/163 (28%), Positives = 74/163 (45%), Gaps = 6/163 (3%)
Frame = +3
Query: 444 QHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTL---MIQLLRG 500
QHPNIV + N +++ E ++T + F VK L Q+L+G
Sbjct: 105 QHPNIVRFFDYWEEHNHRNRKVIILVTELMTSGTLKTYLKRFKKPNVKILKNWCRQVLKG 284
Query: 501 VKHLHDNW--ILHRDLKTSNLLLSH-AGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAP 557
+ LH ++HRDLK N+ ++ G +K+GD GLA V+ T + AP
Sbjct: 285 LYFLHTRTPPVIHRDLKCDNIFITGPTGSVKIGDLGLATLKNQSFAK--SVIGTPEFMAP 458
Query: 558 ELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINK 600
E+ + Y AVD+++ G E+ + + + S QI K
Sbjct: 459 EMY--EEHYDEAVDVYAFGMCMLEMASSEYPYSECSNAAQIYK 581
>12786
Length = 460
Score = 50.1 bits (118), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 38/117 (32%), Positives = 58/117 (49%), Gaps = 23/117 (19%)
Frame = -3
Query: 496 QLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLA----REYGSPLKAYTPVVVT 551
++LR VK LH+ ++H DLK +N +L AG LK+ DFG+A ++ S LK V T
Sbjct: 386 EMLRAVKALHNEGVIHSDLKPANFMLV-AGNLKLIDFGIANTLQQDKTSVLK--DSRVGT 216
Query: 552 QWYRAPELLLGAKE-----------------YSTAV--DMWSVGCIFGELLTQKPLF 589
Y +PE ++ A + Y V D+WS+GCI ++ + F
Sbjct: 215 PSYMSPEAIMAACDDSADDSMEEDGHRTKPKYKVGVRSDVWSLGCILYNMVYGRTPF 45
>17300
Length = 480
Score = 49.7 bits (117), Expect = 4e-06, Method: Composition-based stats.
Identities = 31/90 (34%), Positives = 51/90 (56%), Gaps = 5/90 (5%)
Frame = +1
Query: 500 GVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLK--AYTP---VVVTQWY 554
G+ L D +HRDL N+L++ + KV DFGL+RE S AYT + +W
Sbjct: 10 GMGXLADMGYVHRDLAARNILVNEILVCKVADFGLSREIESDTTEGAYTTKGGKIPVRW- 186
Query: 555 RAPELLLGAKEYSTAVDMWSVGCIFGELLT 584
APE + +++++A D+WS G + E+++
Sbjct: 187 TAPE-AIAYRKFTSASDVWSFGVVMWEVMS 273
>31885
Length = 529
Score = 47.4 bits (111), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 46/161 (28%), Positives = 73/161 (45%), Gaps = 4/161 (2%)
Frame = -2
Query: 437 INTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQ 496
++ + + HP +V + D +V ++ DL+ M+ + F VK + Q
Sbjct: 519 VDMLTRLDHPFLVNLW-YAFQDEEDLFMVVDLFLGGDLRYHMQQ-EVSFREDCVKFYLCQ 346
Query: 497 LLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRA 556
L + +L I+HRD+K N+LL G V DF +A + A T T+ Y A
Sbjct: 345 LALVLDYLRSQKIVHRDIKPDNILLDEQGHCHVTDFNIATQLEDDELA-TSTSGTRPYMA 169
Query: 557 PELLLGA----KEYSTAVDMWSVGCIFGELLTQKPLFPGNS 593
PE+ A + Y VD WS+G ELL ++ F +S
Sbjct: 168 PEVYGVAINERRGYGFPVDWWSLGVSLFELLKKRRPFSVHS 46
>11780
Length = 1713
Score = 46.2 bits (108), Expect = 5e-05, Method: Compositional matrix adjust.
Identities = 51/202 (25%), Positives = 98/202 (48%), Gaps = 4/202 (1%)
Frame = +3
Query: 395 IEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREI 454
I +G +G VY+ + + VA+K+LK +K+ + L+E + + +H N+V + +
Sbjct: 621 IGKGDFGDVYKGMYR--GQPVAIKQLK---DKDRGEQSFLQEASVMTSLRHDNLVRLIGV 785
Query: 455 VVGSNMDKIYIVMNYV-EHDLKSLMETMKQPFLPGEVK-TLMIQLLRGVKHLHDNWILHR 512
V+G + I++V ++ + +L + + + + + + +++L ++HR
Sbjct: 786 VLG---ETIFLVTEFMGKGNLVEYLRSRGRSVITKKDQINFATDTCAAMEYLESKRLVHR 956
Query: 513 DLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEY--STAV 570
DL N+L+ G KV DFGLA+ +G + T V + APE L K + V
Sbjct: 957 DLAARNVLVHDDGKAKVSDFGLAK-FGDF--SQTSVKFPIKWTAPEALRENKIH*QVRHV 1127
Query: 571 DMWSVGCIFGELLTQKPLFPGN 592
++W + + G LL P N
Sbjct: 1128ELWHI--VMGNLLLWSSALP*N 1187
>05084
Length = 1324
Score = 45.1 bits (105), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 28/92 (30%), Positives = 43/92 (46%), Gaps = 4/92 (4%)
Frame = +2
Query: 589 FPGNSEIDQINKVFKELGTPS----EKIWPGYSELPVVKKMTFSEHPYNNLRKRFGALLS 644
PG+S +DQ+ ++ K LGTP+ ++ P YSE K HP+ K F
Sbjct: 2 LPGDSGVDQLVEIIKVLGTPTREQIREMNPNYSEF---KFPQIKAHPWT---KVFRPRTP 163
Query: 645 DQGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 676
+ L+++ L Y P RI + H +F E
Sbjct: 164 PEAIQLVSRLLEYTPSARIQPMEACAHAFFDE 259
>20640
Length = 1492
Score = 44.3 bits (103), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 26/79 (32%), Positives = 40/79 (50%), Gaps = 4/79 (5%)
Frame = +1
Query: 510 LHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYT----PVVVTQWYRAPELLLGAKE 565
+HRDL T N L+ H ++K+ DFGLAR S + Y + +W +L +
Sbjct: 10 VHRDLATRNCLVGHDLVVKISDFGLARSVHS-VDYYRGSEHDAIPIRWMPLEAILYN--K 180
Query: 566 YSTAVDMWSVGCIFGELLT 584
+ST D+WS G + E+
Sbjct: 181 FSTQSDVWSFGVVLWEIFA 237
>07836
Length = 1478
Score = 43.5 bits (101), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 53/190 (27%), Positives = 85/190 (44%), Gaps = 20/190 (10%)
Frame = -1
Query: 413 EIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIV--TVREIVVGSNMDKIYIVMNYV 470
E VA+K +E F T L + T+L +H NI+ +I + +++++ +Y
Sbjct: 1475 ENVAVKIFFTTEEASWFRETELYQ--TVL-LRHENILGFIAADIKGTGSWTQLFLITDY- 1308
Query: 471 EHDLKSLMETMKQPFL-PGEVKTLMIQLLRGVKHLHDNW--------ILHRDLKTSNLLL 521
H+ SL + + L E+ L + G+ HLH I HRD+K+ N+L+
Sbjct: 1307 -HENGSLHDYLLSRVLDSSEMLALAHSAICGLAHLHIEIFGTRGKPAIAHRDIKSKNILV 1131
Query: 522 SHAGILKVGDFGLAREYGSPLK----AYTPVVVTQWYRAP---ELLLGAKEYST--AVDM 572
G + D GLA Y S A P T+ Y AP E+LL K + DM
Sbjct: 1130 KKNGTCCIADLGLAVRYISESNEVDVAPNPRQGTKRYMAPEVLEMLLNVKNFDAFKQADM 951
Query: 573 WSVGCIFGEL 582
++ G + E+
Sbjct: 950 YAFGLVMWEI 921
>17975
Length = 449
Score = 43.5 bits (101), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 35/146 (23%), Positives = 67/146 (45%), Gaps = 10/146 (6%)
Frame = +3
Query: 400 YGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSN 459
+ VV A+ T E VA+K + K E +E+ + QHPN+V + E++
Sbjct: 6 FAVVKLARHVFTGEKVAVKVIDKTKLDEVSRSHLFQEVRCMKLVQHPNVVRLYEVI--DT 179
Query: 460 MDKIYIVM---------NYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWIL 510
K+Y+++ +Y+ L E + + + Q++ + + H ++
Sbjct: 180 QTKLYLILELGDGGDMYDYIMRHSGGLEEKLAKRYFR--------QIVEAISYCHKLHVV 335
Query: 511 HRDLKTSNLLLSHA-GILKVGDFGLA 535
HRDLK N++ G++K+ DFG +
Sbjct: 336 HRDLKPENVVFFEKPGLVKLTDFGFS 413
>21433
Length = 590
Score = 42.0 bits (97), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 33/94 (35%), Positives = 50/94 (53%)
Frame = +2
Query: 494 MIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQW 553
+ QL +++ H ++HRD+K NLLL G LK+ DFG + +P T + T
Sbjct: 185 IYQLSSALEYCHYRKVIHRDIKPENLLLGLKGDLKIADFGWSVH--APSSRRTTMCGTLD 358
Query: 554 YRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKP 587
Y PE++ G K + VD+WS+G + E L P
Sbjct: 359 YLPPEMVEG-KTHDENVDLWSLGVLCYEFLVGTP 457
>07291
Length = 833
Score = 41.6 bits (96), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 28/96 (29%), Positives = 50/96 (52%), Gaps = 6/96 (6%)
Frame = +1
Query: 496 QLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGS--PLKAYT----PVV 549
Q+ G+ +L + ++HR+L N +++ G L++ D+G+ GS P YT P
Sbjct: 73 QIADGMAYLQEVKVVHRNLAARNCIVTEDGRLQLSDYGVT---GSLFPQSYYTADDSPAR 243
Query: 550 VTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQ 585
+ APE + +S+ D+W+ G + ELLT+
Sbjct: 244 DLVKWMAPE-TIDNFHFSSKSDVWAFGVVLWELLTR 348
>15549
Length = 470
Score = 40.4 bits (93), Expect = 0.002, Method: Composition-based stats.
Identities = 18/54 (33%), Positives = 35/54 (64%), Gaps = 1/54 (1%)
Frame = -1
Query: 373 LPKYLPALQ-GCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKE 425
LP P+ + R +EF+C+ ++ +G YG+V+RAK+K ++ A+KR+ + +
Sbjct: 263 LPDKAPSAEFKSRFADEFECIEQMGKGGYGIVFRAKNKVDEQEYAVKRIALPSD 102
>02638
Length = 1490
Score = 39.3 bits (90), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 18/50 (36%), Positives = 30/50 (60%)
Frame = +1
Query: 554 YRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFK 603
+ APE+L G + Y A D+WSVGC+ E+ T +P + + + + +FK
Sbjct: 34 FMAPEVLRG-ESYGRACDVWSVGCVMIEMCTCRPPWNSHDISNHLALIFK 180
>14477
Length = 493
Score = 39.3 bits (90), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 41/147 (27%), Positives = 70/147 (47%), Gaps = 4/147 (2%)
Frame = -1
Query: 394 RIEEGTYGVVYRAKDKKTD-EI-VALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTV 451
++ G +G V + + D EI VA+K LK ++E + K H +IV +
Sbjct: 469 KLGAGNFGSVMKGVCRLDDREIPVAIKVLKNADLDPSVQSELIKEAEVMKKMDHMHIVRL 290
Query: 452 REIVVGSNMDKIYIVMNYVEHDLKSLMETM-KQPFLP-GEVKTLMIQLLRGVKHLHDNWI 509
+ G M +V+ + L L + + K LP + LM Q+ +G+++L N
Sbjct: 289 IGLCEGETM---MLVLELAK--LGPLNKFLPKNKHLPLWNILELMWQVSQGMEYLEANKF 125
Query: 510 LHRDLKTSNLLLSHAGILKVGDFGLAR 536
+HRDL N+LL K+ DFG+++
Sbjct: 124 VHRDLAARNILLCDEHFAKISDFGMSK 44
>37602
Length = 804
Score = 38.9 bits (89), Expect = 0.008, Method: Compositional matrix adjust.
Identities = 20/72 (27%), Positives = 39/72 (54%)
Frame = -1
Query: 461 DKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLL 520
+K++I M Y + + P ++ + + L+G+ +LH +HRD+K +N+L
Sbjct: 300 EKLWIAMEYCGGGSMQDIYHVTGPLTEPQIAFVCRETLKGLHYLHRRGKMHRDIKGANIL 121
Query: 521 LSHAGILKVGDF 532
L+ G +K+ DF
Sbjct: 120 LTEEGDVKLADF 85
Score = 28.9 bits (63), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 13/36 (36%), Positives = 21/36 (58%)
Frame = -2
Query: 372 ELPKYLPALQGCRSVEEFQCLNRIEEGTYGVVYRAK 407
E K +Q +++F+ + R+ GTYG VY+AK
Sbjct: 554 EYKKMQADIQRRNPLDDFELIQRVGSGTYGDVYKAK 447
>16708
Length = 1397
Score = 38.9 bits (89), Expect = 0.008, Method: Compositional matrix adjust.
Identities = 16/52 (30%), Positives = 31/52 (59%)
Frame = -1
Query: 487 PGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREY 538
P V + Q + ++H+H+ ++H D+K N+L+ G K+ D+G+A+ Y
Sbjct: 1097 PAMVCCIAGQXVCALEHIHELGVVHMDVKADNVLVDAHGNCKLTDYGIAQLY 942
>26009
Length = 886
Score = 32.0 bits (71), Expect(2) = 0.008, Method: Compositional matrix adjust.
Identities = 12/33 (36%), Positives = 22/33 (66%)
Frame = +3
Query: 489 EVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLL 521
E K++M QL+ + +H ++HRD+K N+L+
Sbjct: 714 EAKSVMKQLVSALDFMHSKQLVHRDIKPENVLI 812
Score = 25.4 bits (54), Expect(2) = 0.008, Method: Compositional matrix adjust.
Identities = 23/93 (24%), Positives = 35/93 (37%), Gaps = 5/93 (5%)
Frame = +2
Query: 387 EEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREIN-----TIL 441
E + + GTYG V A+ + T VALK L T LRE +
Sbjct: 416 EHYDVCKELGRGTYGKVVLARCRHTGTQVALKLLPKS-------CTKLREFQREFQLSYF 574
Query: 442 KAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDL 474
+ H NI+ + + ++ + V DL
Sbjct: 575 LSPHANIIDTYNVAFQTRSSYVFAQEHAVLGDL 673
>13078
Length = 773
Score = 38.1 bits (87), Expect = 0.012, Method: Compositional matrix adjust.
Identities = 31/125 (24%), Positives = 59/125 (47%), Gaps = 14/125 (11%)
Frame = -1
Query: 566 YSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKI--------WPGYS 617
+S D+WS+GCI EL T LF + + + + + LG+ ++ + +
Sbjct: 746 WSQPCDVWSIGCIMFELYTGYTLFQTHDNKEHLAMMERILGSLPYRMAKKTKKQKYFYHG 567
Query: 618 ELPVVKKMTFSEHPYNNLR--KRFGALLSD----QGFDLMNKFLTYFPGRRISAEDGLKH 671
L +K + + +N++ +R+ + Q FDLM+K L+Y R S ++H
Sbjct: 566 RLDWDEKSSAGRYVRDNVKPLRRYVKDPDNEDHQQLFDLMDKMLSYEVSTRYSLRQAMRH 387
Query: 672 EYFRE 676
+FR+
Sbjct: 386 PFFRK 372
>18481
Length = 437
Score = 38.1 bits (87), Expect = 0.013, Method: Compositional matrix adjust.
Identities = 24/77 (31%), Positives = 38/77 (49%), Gaps = 3/77 (3%)
Frame = -1
Query: 465 IVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLS-- 522
+VM + L+ L K+ F + + QLL ++ +H +HRDLK N L+
Sbjct: 266 LVMELLGPSLEELFVICKRRFTLKTILMVSDQLLSRLEFIHQKCFIHRDLKPDNFLMGLG 87
Query: 523 -HAGILKVGDFGLAREY 538
H L + DFGL++ Y
Sbjct: 86 RHCHRLYIIDFGLSKRY 36
>00486
Length = 797
Score = 35.4 bits (80), Expect = 0.079, Method: Compositional matrix adjust.
Identities = 18/50 (36%), Positives = 27/50 (54%)
Frame = -2
Query: 554 YRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFK 603
Y APE+L + AVD WS+G + ++LT P F + I+K+ K
Sbjct: 760 YMAPEILTRTG-HGKAVDWWSLGALMYDMLTGSPPFTAENRKKTIDKILK 614
>36481
Length = 806
Score = 33.1 bits (74), Expect = 0.38, Method: Compositional matrix adjust.
Identities = 37/149 (24%), Positives = 66/149 (44%), Gaps = 6/149 (4%)
Frame = +2
Query: 379 ALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLK-MEKEKEGFPITSLREI 437
++G S + + EGT+G V + KD + +ALK +K ++K +E + EI
Sbjct: 338 TMRGTSSTNDMKLCPHWGEGTFGKVVQCKDLLKGDDIALKIIKNVDKYREAAKL----EI 505
Query: 438 NTILKAQ----HPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGE-VKT 492
N + K + H + V+ + + I + + + ++ P E V+
Sbjct: 506 NVLEKLREKDPHAKHMCVQMLDWFDYHGHVCISFHMLGLSVFDFLKDNSYGAYPIEQVRH 685
Query: 493 LMIQLLRGVKHLHDNWILHRDLKTSNLLL 521
+ QL V LH+N + H DLK N+L
Sbjct: 686 ISYQLCYAVNFLHENQLTHTDLKPENILF 772
>00145
Length = 2325
Score = 30.8 bits (68), Expect = 1.9, Method: Compositional matrix adjust.
Identities = 18/50 (36%), Positives = 25/50 (50%), Gaps = 1/50 (2%)
Frame = -1
Query: 655 LTYFPGRRISAEDGLKHEYFRETP-LPIDPSMFPTWPAKSEQQRVKRGTS 703
+ P RIS DG + RE+P LP D + P P + Q+ V R T+
Sbjct: 2325 IQVHPQHRISQSDGESVDVQRESPLLPRDGAAVPQRPGPAAQEGVSRQTA 2176
>15931
Length = 447
Score = 30.4 bits (67), Expect = 2.5, Method: Compositional matrix adjust.
Identities = 13/31 (41%), Positives = 19/31 (61%)
Frame = +1
Query: 646 QGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 676
Q FDLM+K L+Y R S ++H +FR+
Sbjct: 70 QLFDLMDKMLSYEVSTRYSLRQAMRHPFFRK 162
>20152
Length = 445
Score = 30.0 bits (66), Expect = 3.6, Method: Compositional matrix adjust.
Identities = 14/33 (42%), Positives = 20/33 (60%)
Frame = +1
Query: 557 PELLLGAKEYSTAVDMWSVGCIFGELLTQKPLF 589
PE+LLG + AVD+WS+G I L+ + F
Sbjct: 1 PEILLGDSYDAPAVDVWSLGVILYMLVVGEAPF 99
>38560
Length = 479
Score = 29.3 bits (64), Expect = 6.2, Method: Composition-based stats.
Identities = 12/30 (40%), Positives = 18/30 (60%)
Frame = -3
Query: 554 YRAPELLLGAKEYSTAVDMWSVGCIFGELL 583
Y APEL+ G + + D+WS+G + LL
Sbjct: 387 YAAPELISGLEYLGSEADIWSMGVLLYALL 298
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000367905 | hsapiens_gene_ensembl | PITSLRE
serine/threonine-protein kinase CDC2L2 (EC 2.7.11.22)
(Galactosyltransferase-associated protein kinase p58/GTA) (Cell
division cycle 2-like protein kinase 2) (CDK11).
[Source:Uniprot/SWISSPROT;Acc:Q9UQ88]
(746 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
29581 292 5e-84
01060 229 3e-60
01756 223 3e-58
14126 219 2e-57
04591 196 4e-50
32000 170 2e-42
01707 162 4e-40
04138 151 1e-36
01966 118 3e-28
23319 103 3e-22
00300 95 1e-19
03294 87 2e-17
18921 86 7e-17
06405 83 4e-16
13592 82 6e-16
12721 82 8e-16
01718 80 4e-15
09606 77 2e-14
03508 77 4e-14
20559 66 1e-13
12453 74 2e-13
14420 73 3e-13
15910 71 2e-12
26560 68 1e-11
19761 65 8e-11
18484 65 8e-11
21578 64 2e-10
27546 63 4e-10
14116 62 9e-10
03240 62 1e-09
30755 61 1e-09
13212 61 2e-09
28638 61 2e-09
13066 60 3e-09
26909 60 3e-09
19094 59 8e-09
21808 58 1e-08
11185 57 4e-08
19301 56 6e-08
27405 56 6e-08
07940 56 7e-08
18287 55 8e-08
26711 55 8e-08
24241 55 9e-08
28157 55 1e-07
31489 55 1e-07
12672 54 3e-07
17253 53 4e-07
04852 53 5e-07
00715 52 1e-06
18401 52 1e-06
21079 51 2e-06
16003 51 2e-06
00392 50 3e-06
12786 50 4e-06
17300 50 4e-06
31885 47 2e-05
11780 46 5e-05
05084 45 1e-04
20640 44 2e-04
07836 44 3e-04
17975 44 3e-04
21433 42 0.001
07291 42 0.001
15549 40 0.002
02638 39 0.005
14477 39 0.006
37602 39 0.008
16708 39 0.008
26009 32 0.008
13078 38 0.012
18481 38 0.013
00486 35 0.079
36481 33 0.38
00145 31 1.9
15931 30 2.5
20152 30 3.6
38560 29 6.2
>29581
Length = 1278
Score = 292 bits (747), Expect(2) = 5e-84, Method: Compositional matrix adjust.
Identities = 133/261 (50%), Positives = 183/261 (70%)
Frame = -2
Query: 440 ILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLR 499
+L +H NIV ++E+VVG ++D +++VM Y E DL SL++ M PF +VK +++QLL+
Sbjct: 1193 LLNLRHQNIVQLQEVVVGKSLDSLFLVMEYCEQDLASLLDNMPAPFSESQVKCIVLQLLK 1014
Query: 500 GVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPEL 559
G+++LH+ +I+HRDLK SNLL++ G +K+ DFGLAR YG P K TP VVT WYRAPEL
Sbjct: 1013 GLRYLHEAFIIHRDLKVSNLLMTDKGCVKIADFGLARNYGKPQKPMTPKVVTLWYRAPEL 834
Query: 560 LLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSEL 619
L G+K +STA+DMWS GCI GELL KPL PG S++ QI + + LGTP++ IWPG+S+L
Sbjct: 833 LFGSKTHSTAIDMWSAGCILGELLGHKPLMPGRSDLQQIELIMELLGTPNDTIWPGFSQL 654
Query: 620 PVVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPL 679
P ++ T + PYNNLR F LS+ G L+N Y P +R +AED L+H YF+E P
Sbjct: 653 PAFEQFTLKKQPYNNLRHTF-PWLSESGIRLLNGLFMYHPQKRATAEDCLEHSYFKEQPY 477
Query: 680 PIDPSMFPTWPAKSEQQRVKR 700
P DP P++P Q R+KR
Sbjct: 476 PCDPEFMPSFP----QHRLKR 426
Score = 38.9 bits (89), Expect(2) = 5e-84, Method: Composition-based stats.
Identities = 17/35 (48%), Positives = 25/35 (71%)
Frame = -1
Query: 412 DEIVALKRLKMEKEKEGFPITSLREINTILKAQHP 446
+EIVALK+++M E+ G PI+ LREIN ++ P
Sbjct: 1278 NEIVALKKMRMTGERYGIPISGLREINIFAQSATP 1174
>01060
Length = 1800
Score = 229 bits (584), Expect = 3e-60, Method: Compositional matrix adjust.
Identities = 122/338 (36%), Positives = 204/338 (60%), Gaps = 2/338 (0%)
Frame = +1
Query: 364 LLPIELKQELPKYLPALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKME 423
LL + +K+ + + AL + +FQ +I EGTYGVVY+ + + T +A+K++++
Sbjct: 22 LLKLNIKRLMMDFETALS---DLTDFQ---KIGEGTYGVVYKCRHRATGRKLAMKKIRLR 183
Query: 424 KEKEGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQ 483
++G P +++REI + + +H NIV + ++++ +++++V ++ DLK ++ +
Sbjct: 184 GSEDGVPSSAIREIAMLRELRHTNIVCLEDVIMED--ERLFLVFEFLSMDLKMYIDKFPE 357
Query: 484 PFLPGE--VKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSP 541
+ VK+ + Q++ G+ H I+HRDLK NLL++H G +K+ DFG+AR + P
Sbjct: 358 GVVLDRRLVKSYVFQIVTGIXFCHQRRIVHRDLKPQNLLINHTGAIKIADFGMARTFALP 537
Query: 542 LKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKV 601
++AYT VVT WYRAPE+L+GA +YST VD+WS+G IF ++L + P+F G+SEIDQ+ K+
Sbjct: 538 VRAYTHEVVTLWYRAPEILMGASKYSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKI 717
Query: 602 FKELGTPSEKIWPGYSELPVVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGR 661
F+ +GTP+E+ WP + +LP M F L + L S G DL+ + L P +
Sbjct: 718 FRIIGTPTEQTWPEFHKLPAFNGM-FPLWKEGKLSETLTDLDS-LGLDLIERTLKCDPAQ 891
Query: 662 RISAEDGLKHEYFRETPLPIDPSMFPTWPAKSEQQRVK 699
RIS + L+H YF + P P+ P S R+K
Sbjct: 892 RISCKKMLQHAYFLNVDTSVKPVDVPS-PEHS*STRLK 1002
>01756
Length = 1858
Score = 223 bits (567), Expect = 3e-58, Method: Compositional matrix adjust.
Identities = 117/309 (37%), Positives = 187/309 (60%), Gaps = 10/309 (3%)
Frame = -3
Query: 383 CRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILK 442
C +++ L +I +GT+G V++A+ KKT ++VA+K++ M+ EKEGFPIT+LREI +
Sbjct: 1754 CDEDAKYEKLAKIGQGTFGEVFKARCKKTKQVVAMKKVLMDNEKEGFPITALREIKILQL 1575
Query: 443 AQHPNIVTVREIV----VGSNMDK--IYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQ 496
H N+V + EI +N K Y+V + EHDL L+ M F E+K +M Q
Sbjct: 1574 LNHENVVDLIEICSTKATSANRYKSMFYLVFEFCEHDLAGLLSNMSVVFNLPEIKEVMKQ 1395
Query: 497 LLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKA---YTPVVVTQW 553
L+ G+ ++H N ILHRD+K +N+L++ G+LK+ DFGLAR + L+ YT VVT W
Sbjct: 1394 LMNGLYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLW 1215
Query: 554 YRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIW 613
YR PELLLG + YSTA+D W GCI E+ T+ P+ G +E +Q+ + + G+ + ++W
Sbjct: 1214 YRPPELLLGDRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQNQLTLITQLCGSITPEVW 1035
Query: 614 PGYSELPVVKKMTFSEHPYNNLRKRFGALLSDQ-GFDLMNKFLTYFPGRRISAEDGLKHE 672
PG L + + + +++R + D DL++K L PG+R+++++ L H+
Sbjct: 1034 PGVERLELYNSLDLPQGNKRKVKERLRYYIKDAYALDLLDKLLALDPGKRVNSDEALSHD 855
Query: 673 YFRETPLPI 681
+F P P+
Sbjct: 854 FFWMDPEPL 828
>14126
Length = 1265
Score = 219 bits (559), Expect = 2e-57, Method: Compositional matrix adjust.
Identities = 125/299 (41%), Positives = 182/299 (60%), Gaps = 9/299 (3%)
Frame = +3
Query: 387 EEFQCLNRIEEGTYGVVYRAKD-KKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQ- 444
++++ + I G YG VY+A+D + E VA+KR+++ +EG P+ ++REI+ + + +
Sbjct: 189 QKYEEVAVIGNGAYGTVYKARDLRNQGEFVAMKRIRLNNTEEGMPMMAIREISMLKQLEQ 368
Query: 445 --HPNIVTVREIVVGSNMDK---IYIVMNYVEHDLKSLMETMKQPFL-PGEVKTLMIQLL 498
HPN+V + ++ + D+ + +V Y+EHDL + + P L P +K LM+QLL
Sbjct: 369 YEHPNVVRLLDVSHNTITDREIRLNLVFEYIEHDLATYLAKCPSPGLGPDRIKDLMLQLL 548
Query: 499 RGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPE 558
GV LH N I+HRDLK NLL+S G LK+ DFGLAR Y + A T VVVT WYR+PE
Sbjct: 549 NGVDFLHSNRIVHRDLKPQNLLISKDGRLKLADFGLARIYSFHM-ALTTVVVTLWYRSPE 725
Query: 559 LLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWP-GYS 617
+L+ A EY T+VD+WS GCIF EL T++ LF G+SE DQ+ K+F+ +G P WP G S
Sbjct: 726 VLMQA-EYGTSVDIWSCGCIFAELFTRRALFKGSSEFDQLKKIFEVIGLPPAGDWPEGVS 902
Query: 618 ELPVVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 676
V + +F P L+ + Q DLM K L + GRRIS+ + L H Y R+
Sbjct: 903 ----VHRNSFRPTPPVPLQTLVPE-MDPQAKDLMEKMLVFKSGRRISSRESLLHPYLRD 1064
>04591
Length = 1117
Score = 196 bits (497), Expect = 4e-50, Method: Compositional matrix adjust.
Identities = 102/267 (38%), Positives = 161/267 (60%), Gaps = 7/267 (2%)
Frame = -2
Query: 426 KEGFPITSLREINTILKAQHPNIVTVREIV------VGSNMDKIYIVMNYVEHDLKSLME 479
KEGFPIT+LREI + + +H N+V ++EI Y++ Y ++DL L+
Sbjct: 1101 KEGFPITALREIKILQQLEHENVVQLQEICHTQAGPYNRYKSTFYLIFEYCDYDLAGLLN 922
Query: 480 TMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYG 539
++ F + K LM QLL G+ ++H ILHRD+K +N+LL+ G+LK+ DFGL+R +
Sbjct: 921 NLRVKFSLADKKNLMSQLLNGLFYIHTKQILHRDIKAANILLTRDGVLKLADFGLSRPWV 742
Query: 540 SPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQIN 599
K T VVT WYR PELLLG +EY +DMW VGCI E+ ++KPL G SE Q++
Sbjct: 741 KS-KRLTNRVVTLWYRPPELLLGEREYGPEIDMWGVGCIMAEMWSRKPLMQGRSEQHQLS 565
Query: 600 KVFKELGTPSEKIWPGYSELPVVKKMTFSEHPYNNLRKRFGALLSD-QGFDLMNKFLTYF 658
+ G+ + ++WPG ++L + K+ + +++R LL + +G +L++ FL
Sbjct: 564 LITDLCGSLNAEVWPGVTKLELYGKLDLPQGKPRKVKERMLDLLKNKEGAELIDIFLRLD 385
Query: 659 PGRRISAEDGLKHEYFRETPLPIDPSM 685
PG+R++ ++ L H++F PLP PS+
Sbjct: 384 PGQRMNCDNALSHDFFWVDPLP-SPSL 307
>32000
Length = 644
Score = 170 bits (431), Expect = 2e-42, Method: Compositional matrix adjust.
Identities = 79/150 (52%), Positives = 106/150 (70%)
Frame = -1
Query: 527 LKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQK 586
+K+ DFGLAR +G P++ YT V+T WYRAPE+LLG + YS VD+WS+GCIF E++T++
Sbjct: 572 MKIADFGLARVFGLPVRTYTHEVITLWYRAPEILLGCRFYSVPVDIWSLGCIFVEMMTRR 393
Query: 587 PLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKMTFSEHPYNNLRKRFGALLSDQ 646
LFPG+SEIDQ+ ++F+ LGTP EK+WPG S+LP K TF + P NL LS
Sbjct: 392 ALFPGDSEIDQLYRIFRTLGTPDEKVWPGVSKLPDYKP-TFPKWPLKNLETVVS--LSKV 222
Query: 647 GFDLMNKFLTYFPGRRISAEDGLKHEYFRE 676
G DL+ + LTY P RRISA ++H YF +
Sbjct: 221 GLDLLKRMLTYNPNRRISARSAMRHPYFND 132
>01707
Length = 757
Score = 162 bits (411), Expect = 4e-40, Method: Compositional matrix adjust.
Identities = 81/221 (36%), Positives = 138/221 (62%)
Frame = +1
Query: 386 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 445
+E+++ + +I EG+YGVV++ ++K+T ++VA+K+ ++ ++REI + + +H
Sbjct: 61 MEKYEKIGKIGEGSYGVVFKCRNKETSQLVAIKKFVESEDDPLIKKIAMREIRMLKQLKH 240
Query: 446 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLH 505
PN+V R I V ++++V +YV+H L + ++ + VK ++ Q L V H
Sbjct: 241 PNLV--RLIEVFRRKKRLHLVFDYVDHTLLNELDRYPRGLPEPMVKRIIYQTLLAVNFCH 414
Query: 506 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKE 565
+HRD+K N+L++ G +K+ DFG AR P YT V T+WYRAPELL+G +
Sbjct: 415 QYNTIHRDVKPENILITRQGQVKLCDFGFARILTGPGDEYTDYVATRWYRAPELLVGDTQ 594
Query: 566 YSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELG 606
Y VD+W++GC+F ELLT + L+PG S++DQ++ + K LG
Sbjct: 595 YGPPVDVWAIGCVFAELLTGQALWPGRSDVDQLHLIRKTLG 717
>04138
Length = 800
Score = 151 bits (381), Expect = 1e-36, Method: Compositional matrix adjust.
Identities = 72/178 (40%), Positives = 111/178 (62%), Gaps = 6/178 (3%)
Frame = +1
Query: 503 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKA---YTPVVVTQWYRAPEL 559
++H N ILHRD+K +N+L++ G+LK+ DFGLAR + L+ YT VVT WYR PEL
Sbjct: 58 YIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRPPEL 237
Query: 560 LLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSEL 619
LLG + YSTA+D W GCI E+ T+ P+ G +E +Q+ + + G+ + ++WPG ++L
Sbjct: 238 LLGDRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQNQLTLITQLCGSITPEVWPGVTQL 417
Query: 620 PVVKKM--TFSEHPYNNLRKRFGALLSD-QGFDLMNKFLTYFPGRRISAEDGLKHEYF 674
+ ++ + N +R RF +L D G DL + L P +RISA++ L H++F
Sbjct: 418 SMYHQIKGALAAGRKNIIRDRFARILKDPYGLDLFERLLKMDPSQRISADEALNHDFF 591
>01966
Length = 1735
Score = 118 bits (296), Expect(2) = 3e-28, Method: Compositional matrix adjust.
Identities = 55/175 (31%), Positives = 107/175 (61%), Gaps = 2/175 (1%)
Frame = -1
Query: 406 AKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYI 465
+ + T +A+K++++ ++G P +++REI + + +H NIV + ++++ +++++
Sbjct: 1654 CRHRATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTNIVCLEDVIMED--ERLFL 1481
Query: 466 VMNYVEHDLKSLMETMKQPFLPGE--VKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSH 523
V ++ DLK ++ + + VK+ + Q++ G+ H I+HRDLK NLL++H
Sbjct: 1480 VFEFLSMDLKMYIDKFPEGVVLDRRLVKSYVFQIVTGINFCHQRRIVHRDLKPQNLLINH 1301
Query: 524 AGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCI 578
G +K+ DFG+AR + P++AYT VVT WYRAPE+L+G + + W+ G +
Sbjct: 1300 TGAIKIADFGMARTFALPVRAYTHEVVTLWYRAPEILMGPQ---STPPXWTCGAL 1145
Score = 25.4 bits (54), Expect(2) = 3e-28, Method: Composition-based stats.
Identities = 10/13 (76%), Positives = 12/13 (92%)
Frame = -2
Query: 392 LNRIEEGTYGVVY 404
L++I EGTYGVVY
Sbjct: 1695 LSKIGEGTYGVVY 1657
Score = 97.8 bits (242), Expect = 1e-20, Method: Compositional matrix adjust.
Identities = 54/138 (39%), Positives = 80/138 (57%)
Frame = -3
Query: 562 GAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPV 621
GA +YST VD+WS+G IF ++L + P+F G+SEIDQ+ K+F+ +GTP+E+ WP + +LP
Sbjct: 1187 GASKYSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKLPA 1008
Query: 622 VKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPI 681
M F L + L S G DL+ + L P +RIS + L+H YF +
Sbjct: 1007 FNGM-FPLWKEGKLSETLTDLDS-LGLDLIERTLKCDPAQRISCKKMLQHAYFLNVDTSV 834
Query: 682 DPSMFPTWPAKSEQQRVK 699
P P+ P +S R+K
Sbjct: 833 KPVDVPS-PEQS*STRLK 783
>23319
Length = 2235
Score = 103 bits (256), Expect = 3e-22, Method: Compositional matrix adjust.
Identities = 50/117 (42%), Positives = 72/117 (61%), Gaps = 1/117 (0%)
Frame = +3
Query: 563 AKEYSTAVDMWSVGCIFGELLTQ-KPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPV 621
AK YST++DMWS GCIF EL +PLFPGN + DQ+ ++FK LGTP+E WPG ++LP
Sbjct: 18 AKMYSTSIDMWSAGCIFAELANAGRPLFPGNDDDDQLKRIFKLLGTPTEDQWPGMTQLPN 197
Query: 622 VKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETP 678
+ F + ++ L+ +G DL+ L P R+SA++ L+H YF + P
Sbjct: 198 YR--MFPMYHVTTTWQQVVPKLNSKGRDLLQCLLVCCPSDRMSADEALQHPYFADLP 362
>00300
Length = 2318
Score = 95.1 bits (235), Expect = 1e-19, Method: Compositional matrix adjust.
Identities = 66/207 (31%), Positives = 108/207 (52%), Gaps = 13/207 (6%)
Frame = -1
Query: 393 NRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKA----QHPNI 448
N+I EG +G VY A + T E++ALK +K + + LRE+ +K QH N+
Sbjct: 1640 NKIGEGQFGKVYTAVNMSTGELMALKEMKFQPND----LQQLREMCDEIKIFEGIQHENL 1473
Query: 449 VTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNW 508
V + V + D++ + M Y D ++ E K ++ +++ V HLH+N
Sbjct: 1472 VKYYGVEV--HKDEMLMFMEYC--DTGTIEEAAKMGLPEYLIRRYTREIVLAVNHLHENS 1305
Query: 509 ILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTP-------VVVTQWYRAPELLL 561
I+HRD+K +N+ L+ G +K+GDFG + + LK++T +V T Y APE+
Sbjct: 1304 IVHRDIKGANIFLTSNGHVKLGDFGCSVK----LKSHTTMPGEFHNLVGTTAYMAPEVFT 1137
Query: 562 GAKE--YSTAVDMWSVGCIFGELLTQK 586
+ Y A D+WS+GC+ E+ T K
Sbjct: 1136 QNDQGGYGRAADIWSLGCVVIEMATGK 1056
>03294
Length = 1684
Score = 87.4 bits (215), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 49/130 (37%), Positives = 73/130 (56%)
Frame = -1
Query: 570 VDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKMTFSE 629
VD+WS+G IF ++L + P+F G+SEIDQ+ K+F+ +GTP+E+ WP + +LP M F
Sbjct: 1672 VDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKLPAFNGM-FPL 1496
Query: 630 HPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSMFPTW 689
L + L S G DL+ + L P +RIS + L+H YF + P P+
Sbjct: 1495 WKEGKLSETLTDLDS-LGLDLIERTLKCDPAQRISCKKMLQHAYFLNVDTSVKPVDVPS- 1322
Query: 690 PAKSEQQRVK 699
P S R+K
Sbjct: 1321 PEHS*STRLK 1292
>18921
Length = 697
Score = 85.5 bits (210), Expect = 7e-17, Method: Compositional matrix adjust.
Identities = 57/205 (27%), Positives = 109/205 (53%), Gaps = 6/205 (2%)
Frame = +2
Query: 389 FQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNI 448
F L ++ EG+YG V+++ K+T +++A+K++ ++ + + ++EI+ + + I
Sbjct: 35 FDILGKLGEGSYGSVFKSLHKETGQVLAIKQVPVDTDLQEI----IKEISIMQQCDSKYI 202
Query: 449 VTVREIVVGS---NMDKIYIVMNYV-EHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHL 504
V GS N D ++IVM Y + +M + + E+ T++ L+G+ +L
Sbjct: 203 VKYY----GSYFKNTD-LWIVMEYCGAGSVSDIMRLRNKTLVEREIATILYYTLKGLXYL 367
Query: 505 HDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELL--LG 562
H +HRD+K N+LL++ G K+ DFG+A + + V+ T ++ APE++ +G
Sbjct: 368 HSRRKIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTPYWMAPEVIQEIG 547
Query: 563 AKEYSTAVDMWSVGCIFGELLTQKP 587
Y D+WS+G E+ KP
Sbjct: 548 ---YDCVADIWSLGITALEMAEGKP 613
>06405
Length = 1965
Score = 83.2 bits (204), Expect = 4e-16, Method: Compositional matrix adjust.
Identities = 63/205 (30%), Positives = 102/205 (49%), Gaps = 8/205 (3%)
Frame = +1
Query: 388 EFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILK-AQHP 446
E +R+ G YG VY A K+ ++IVA+K LK ++ + E I+K +HP
Sbjct: 262 EIAMKHRLGGGQYGDVYEAMWKRYNKIVAVKTLK----EDTMALNDFLEEAAIMKEMKHP 429
Query: 447 NIVTVREIVVGSNMDKIYIVMNYVEHD--LKSLMETMKQPFLPGEVKTLMIQLLRGVKHL 504
N+V + + V + YIV ++ H L L + ++ P + + Q+ G+ +L
Sbjct: 430 NLVQL--LGVCTREPPFYIVTEFMPHGNLLDYLRSSTREENGPTALMYMATQIASGMAYL 603
Query: 505 HDNWILHRDLKTSNLLLSHAGILKVGDFGLAR-----EYGSPLKAYTPVVVTQWYRAPEL 559
+HRDL N L++ + ++KV DFGLAR Y + + A P+ +W APE
Sbjct: 604 ETKNFIHRDLAARNCLVADSNMVKVADFGLARLMKDDTYTAHIGAKFPI---KW-TAPE- 768
Query: 560 LLGAKEYSTAVDMWSVGCIFGELLT 584
L +ST D+W+ G + EL T
Sbjct: 769 GLAFNRFSTRSDIWAFGVLLWELAT 843
>13592
Length = 980
Score = 82.4 bits (202), Expect = 6e-16, Method: Compositional matrix adjust.
Identities = 80/295 (27%), Positives = 138/295 (46%), Gaps = 13/295 (4%)
Frame = +2
Query: 394 RIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVRE 453
+I +G +G VY A + T E++A+K + ++ + E+ + +H N+V
Sbjct: 5 KIGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETRALKNVAEELKILEGIKHKNLVRYYG 184
Query: 454 IVVGSNMDKIYIVMNYV-EHDLKSLMETMKQPFLPGEV-KTLMIQLLRGVKHLHDNWILH 511
I V + +++ I M E L+SL+E LP + + QLL GV LH + I+H
Sbjct: 185 IEV--HREELLIFMELCSEGTLESLVELTGG--LPEALSRRFTAQLLSGVAELHKHGIVH 352
Query: 512 RDLKTSNL-LLSHAGILKVGDFGLAREYGSPLKAYTPV-------VVTQWYRAPELL--L 561
RD+KT+N+ L+ + LK+GDFG A + ++A+T V V TQ Y APE+
Sbjct: 353 RDIKTANIFLVDGSNSLKLGDFGSAVK----IQAHTTVPGELQGYVGTQAYMAPEVFTKT 520
Query: 562 GAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGY-SELP 620
+ + D+WSVGC+ E+ + K + W + S
Sbjct: 521 NSDGHGRLADIWSVGCVVVEMASGK------------------------RPWAQFDSNFQ 628
Query: 621 VVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFR 675
++ K+ E P + LS +G D ++ L + P +R+SA + L+ + +
Sbjct: 629 IMFKVGMGEKP------QAPESLSQEGHDFIDHCLQHDPKQRLSAIELLEQNFCK 775
>12721
Length = 821
Score = 82.0 bits (201), Expect = 8e-16, Method: Compositional matrix adjust.
Identities = 53/196 (27%), Positives = 106/196 (54%)
Frame = +1
Query: 394 RIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVRE 453
+I EG+ G+V A + ++ A+K++ + K++ + E+ + HPNIV +
Sbjct: 109 KIGEGSTGIVCIATSRDGRQM-AVKKMDLRKQQRRELL--FNEVVVMRDYHHPNIVEMYN 279
Query: 454 IVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRD 513
+ + D++++VM ++E + + T + ++ T+ L+ + LH N ++HRD
Sbjct: 280 SYLVN--DELWVVMEFMEGGALTDIVTNNR-MDEVQIATVCRACLKALAFLHANGVIHRD 450
Query: 514 LKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMW 573
+K+ ++LLSH G +K+ DFG + L+ +V T ++ APE ++ Y VD+W
Sbjct: 451 IKSDSILLSHDGKVKLXDFGFCAQVTQDLQKRKSLVGTPYWMAPE-VISRLPYGPEVDIW 627
Query: 574 SVGCIFGELLTQKPLF 589
S+G + E++ +P F
Sbjct: 628 SLGIMVMEMIDAEPPF 675
>01718
Length = 959
Score = 79.7 bits (195), Expect = 4e-15, Method: Compositional matrix adjust.
Identities = 60/218 (27%), Positives = 107/218 (49%), Gaps = 6/218 (2%)
Frame = +3
Query: 379 ALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREIN 438
A+ +++F C +I G + V++ + T +++ALK M + LRE+
Sbjct: 126 AVSALTRLDDFIC-EKIGAGFFSEVFKVTHRITGQVMALKMNTMTSNRHNM----LREVQ 290
Query: 439 TILKAQHPNIVTVREIVVGSNMDKIYIVMNYV-EHDLKSLMETMKQPFLPGEVKTLMIQL 497
+ + QH NI+ + V +++ + Y+ +L+ L+E + + L + L
Sbjct: 291 LLNRLQHANILRFMGVCVHEG--QLHALTEYIPSGNLEQLLEKKDEELPWTQRIQLTLGL 464
Query: 498 LRGVKHLHDNWILHRDLKTSNLLL----SHAGILKVGDFGLAREYGSPL-KAYTPVVVTQ 552
RG+ +LH +HRDL + N+L+ +H + DFGLA + PL K P V +
Sbjct: 465 ARGLDYLHSTRFIHRDLTSKNILIRREDNHGYHAVIADFGLATKIPDPLDKEKLPTVGSP 644
Query: 553 WYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFP 590
++ APE+L G Y+ D++SVG I E+ + P P
Sbjct: 645 YWMAPEVLNG-HFYNERADLFSVGIIMCEITARIPADP 755
>09606
Length = 1300
Score = 77.4 bits (189), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 82/314 (26%), Positives = 134/314 (42%), Gaps = 24/314 (7%)
Frame = -3
Query: 386 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 445
+E F + +G + ++Y+ + K T VA+ + EK K ++R + I H
Sbjct: 1118 MENFVLYEELGKGEHSIIYKGRRKGTINFVAIHCI--EKCKRPEVTNTVRMTHDI---SH 954
Query: 446 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPF-LP-GEVKTLMIQLLRGVKH 503
PN+V E SN +++V+ SL + + Q LP ++ I L+ G+ +
Sbjct: 953 PNVVQFHEWYETSN--HLWLVVELCTGG--SLADILAQDHHLPETSIRDFGIHLVTGLHY 786
Query: 504 LHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAY------------------ 545
+H IL DL+ S +LL +G+LK DFGL++ G L+
Sbjct: 785 IHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQWNIQSAEE 606
Query: 546 ----TPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKV 601
P + Y APE+ GA E S D+W++GC+F E+ + P F G + +KV
Sbjct: 605 MMKQVPTSGSPTYMAPEVFQGA-EPSIMSDLWALGCVFYEMFSGHPPFLGETYDITKDKV 429
Query: 602 FKELGTPSEKIWPGYSELPVVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGR 661
K +P LP VK S P S + +L+ L R
Sbjct: 428 LN-------KEFP----LPKVKGSRLSAKP------------SPEFLNLLESLLQKDSTR 318
Query: 662 RISAEDGLKHEYFR 675
R+S +KH +++
Sbjct: 317 RLSWASLVKHAFWQ 276
>03508
Length = 1463
Score = 76.6 bits (187), Expect = 4e-14, Method: Compositional matrix adjust.
Identities = 39/122 (31%), Positives = 72/122 (59%), Gaps = 2/122 (1%)
Frame = +1
Query: 471 EHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGI-LKV 529
EH + + + Q F +++ + +L++ + H I+HRD+K N+++ H L++
Sbjct: 820 EHVNNTDFKQLYQTFTDYDIRFYLYELMKALDFCHSMGIMHRDVKPHNVMIDHENKKLRL 999
Query: 530 GDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQK-PL 588
D+GLA E+ P Y V +++++ PELLL + Y ++DMWS+GC+F ++ +K PL
Sbjct: 1000IDWGLA-EFYHPGMEYNVRVASRYFKGPELLLDYQMYDYSLDMWSLGCMFASMIFRKEPL 1176
Query: 589 FP 590
P
Sbjct: 1177LP 1182
Score = 35.0 bits (79), Expect = 0.099, Method: Compositional matrix adjust.
Identities = 27/114 (23%), Positives = 51/114 (44%), Gaps = 12/114 (10%)
Frame = +2
Query: 573 WSVG----CIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKMTFS 628
W+ G C+ + P F G+ DQ+ ++ K LGT + ++ + + F+
Sbjct: 1118 WTCGVWAACLPA*SSGKSPFFHGHDNYDQLVRIAKVLGT--DDLYGYIEKYQIDLDPRFN 1291
Query: 629 EHPYNNLRKRF--------GALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYF 674
+ + RKR+ L+S + D ++K L Y R++A + + H YF
Sbjct: 1292 DILGRHSRKRWERFVHSENQHLISPEALDFLDKLLRYDHNERLTAREAMDHPYF 1453
>20559
Length = 430
Score = 65.9 bits (159), Expect(2) = 1e-13, Method: Compositional matrix adjust.
Identities = 31/82 (37%), Positives = 58/82 (70%)
Frame = -2
Query: 374 PKYLPALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITS 433
P +L + +++++ L +I EGTYG V++AK+++T EIVALKR++++ + EG P ++
Sbjct: 414 PTHLHSF*LKHKMQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSA 235
Query: 434 LREINTILKAQHPNIVTVREIV 455
LREI + + +H NIV + +++
Sbjct: 234 LREICLLKELKHRNIVRLHDVL 169
Score = 29.3 bits (64), Expect(2) = 1e-13, Method: Composition-based stats.
Identities = 14/36 (38%), Positives = 19/36 (52%)
Frame = -3
Query: 469 YVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHL 504
Y + DLK +T P VK+ + QLLRG+ L
Sbjct: 134 YCDQDLKKYFDTCNGEIDPDTVKSFLHQLLRGLGFL 27
>12453
Length = 680
Score = 73.9 bits (180), Expect = 2e-13, Method: Composition-based stats.
Identities = 41/100 (41%), Positives = 55/100 (55%)
Frame = +3
Query: 575 VGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKMTFSEHPYNN 634
VGCIF E+ +PLFPG++ D+++ +FK LGTP+E P S P + +
Sbjct: 6 VGCIFYEMACGRPLFPGSTVEDELHLIFKTLGTPTEDSLPSISRNPDFLALNLPHYQGEA 185
Query: 635 LRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYF 674
L L SD G DL+ KFL Y R+SA D LKH +F
Sbjct: 186 LITIAPRLDSD-GLDLLAKFLKYNAKIRVSAADSLKHSFF 302
>14420
Length = 528
Score = 73.2 bits (178), Expect = 3e-13, Method: Compositional matrix adjust.
Identities = 44/156 (28%), Positives = 90/156 (57%), Gaps = 2/156 (1%)
Frame = +2
Query: 434 LREINTILKAQHPNIVT-VREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLP-GEVK 491
+ EI + + Q+PNIV + +VG +++++VM ++ SL + + + + G++
Sbjct: 44 INEILVMRENQNPNIVNYLDSYLVG---EELWVVMEFLAGG--SLTDVVTETCMDEGQIA 208
Query: 492 TLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVT 551
+ + L+ ++ LH+N ++HRD+K+ N+LL G +K+ DFG + + +V T
Sbjct: 209 AVCRECLQALEFLHENQVIHRDIKSDNILLGMDGSVKLTDFGFCAQLSPEQSKRSTMVGT 388
Query: 552 QWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKP 587
++ APE ++ K+Y VD+WS+G + E++ +P
Sbjct: 389 PYWMAPE-VVTRKQYGPTVDIWSLGVMCIEMIEGEP 493
>15910
Length = 1361
Score = 70.9 bits (172), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 49/125 (39%), Positives = 67/125 (53%), Gaps = 3/125 (2%)
Frame = +2
Query: 497 LLRGVKHLHDNWILHRDLKTSNLL---LSHAGILKVGDFGLAREYGSPLKAYTPVVVTQW 553
+L GV+++H N ++HRDLK NLL ++ LK+ DFGL+R P + V T
Sbjct: 491 ILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLADFGLSR-IIEPEVQMSTVCGTPG 667
Query: 554 YRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIW 613
Y APE+L G K Y+ +VDMWSVG I LL F +E + K+ K E+ W
Sbjct: 668 YCAPEVLKGDK-YTPSVDMWSVGVIAYILLCGYEPFFAENEFEMYRKIIKGEYKFDEEYW 844
Query: 614 PGYSE 618
SE
Sbjct: 845 SEISE 859
>26560
Length = 398
Score = 68.2 bits (165), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 37/119 (31%), Positives = 66/119 (55%), Gaps = 4/119 (3%)
Frame = -1
Query: 485 FLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKA 544
F EV+ +++ G++H+H ++++RDLK +N+LL G +++ D GLA ++ K
Sbjct: 365 FTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGLACDFSK--KR 192
Query: 545 YTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLF----PGNSEIDQIN 599
V T Y APE+L+ + Y ++ D +S GC+ +LL F G + ID++
Sbjct: 191 PHASVGTHGYMAPEVLMKGQSYDSSADWFSFGCMLYKLLKGHSPFRQHNQGQARIDRMT 15
>19761
Length = 473
Score = 65.5 bits (158), Expect = 8e-11, Method: Compositional matrix adjust.
Identities = 36/104 (34%), Positives = 60/104 (57%)
Frame = -3
Query: 503 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLG 562
H H ILHRDLK N+ ++ G +++GD GLAR+ P T V T Y +PE +L
Sbjct: 372 HTHTPVILHRDLKPQNIYVTEKGDVRLGDLGLARKLTGPADFATSQVGTIMYLSPE-ILS 196
Query: 563 AKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELG 606
+ Y++ D+WS+GC+F ++ +K G+ E+ + + + +G
Sbjct: 195 QQPYNSKSDIWSLGCVFYDITGKK----GSDEMGVMFLLVQVMG 76
>18484
Length = 635
Score = 65.5 bits (158), Expect = 8e-11, Method: Compositional matrix adjust.
Identities = 35/99 (35%), Positives = 55/99 (55%)
Frame = +1
Query: 496 QLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYR 555
++ G+ LHD I++RDLK N++L G +K+ DFG+ +E + T Y
Sbjct: 67 EIAVGLFFLHDQGIIYRDLKLDNVMLDSEGHIKIADFGMCKEGMTGDATTRTFCGTPDYI 246
Query: 556 APELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSE 594
APE++L + YS +VD W+ G + E+L +P F G E
Sbjct: 247 APEIVL-YQPYSKSVDWWAYGVLLFEMLAGQPPFDGEDE 360
>21578
Length = 524
Score = 63.9 bits (154), Expect = 2e-10, Method: Composition-based stats.
Identities = 26/33 (78%), Positives = 31/33 (93%)
Frame = +2
Query: 369 LKQELPKYLPALQGCRSVEEFQCLNRIEEGTYG 401
LK++LP YLPA+QGCR+VEEF C+NRIEEGTYG
Sbjct: 425 LKEDLPVYLPAIQGCRNVEEFHCMNRIEEGTYG 523
>27546
Length = 426
Score = 62.8 bits (151), Expect = 4e-10, Method: Composition-based stats.
Identities = 38/113 (33%), Positives = 60/113 (53%), Gaps = 2/113 (1%)
Frame = -1
Query: 426 KEGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQ-- 483
K+ FP RE+ + + HPNI+ + I+ KI+I M Y E ++ +K+
Sbjct: 348 KKFFP----RELEILTRLDHPNIIQIHSIL--QRGPKIFIFMRYAEKG--DMLSHIKKTG 193
Query: 484 PFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAR 536
P + K Q+ + +++LH + I HRDLK N+LLS +K+ DFG AR
Sbjct: 192 PIDEAQTKVWFFQMAKALQYLHSHDIAHRDLKCENILLSKRLNVKIADFGFAR 34
>14116
Length = 1017
Score = 62.0 bits (149), Expect = 9e-10, Method: Compositional matrix adjust.
Identities = 61/205 (29%), Positives = 99/205 (48%), Gaps = 14/205 (6%)
Frame = -1
Query: 395 IEEGTYGVVYRA----KDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVT 450
I +G +G V R ++K D +VA+K L +E + L+E + H N++T
Sbjct: 612 IGKGNFGCVKRGFLTLPEQKGDILVAVKTLHNNNPREIELQSFLQEALIMKDFHHSNVLT 433
Query: 451 VREIVVGSNMDKI-YIVMNYVEHD--LKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDN 507
+ I + N+D + +V+ +++H L + + QP + ++ + + RG+ +L
Sbjct: 432 LIGICL--NLDDMPLVVLPFMKHGDLLTYIRDDQHQPTIK-DLIMYGVDIARGMDYLAGL 262
Query: 508 WILHRDLKTSNLLLSHAGILKVGDFGLAR-----EYGSP--LKAYTPVVVTQWYRAPELL 560
+HRDL N +L +KV DFGLAR EY S KA PV +W L
Sbjct: 261 KFVHRDLAARNCMLDEDFHVKVADFGLARDIYEKEYYSSENKKAKLPV---KWMALESLE 91
Query: 561 LGAKEYSTAVDMWSVGCIFGELLTQ 585
G Y + D+WS G + ELLT+
Sbjct: 90 KG--NYDSKTDVWSYGVVLWELLTR 22
>03240
Length = 1683
Score = 61.6 bits (148), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 62/262 (23%), Positives = 105/262 (40%), Gaps = 48/262 (18%)
Frame = -3
Query: 389 FQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNI 448
F+ + + G +G V + T + A+K L+ + + ++ IL A+ N
Sbjct: 1285 FEKIKTLGVGAFGEVSLCRKNDTGMLYAMKTLRKSDVLKRNQVAHVKAERDIL-AEADNE 1109
Query: 449 VTVREIVVGSNMDKIYIVMNYVEH-DLKSL---METMKQPFLPGEVKTLMIQLLRGVKHL 504
V+ + + +Y VM+YV DL L ME + +P + + +L++ ++ +
Sbjct: 1108 WVVKLYYSFQDHNYLYFVMDYVPGGDLMGLLIRMEILDEPL----ARFYVAELVQAIESV 941
Query: 505 HDNWILHRDLKTSNLLLSHAGILKVGDFGL-------------------AREYGSPLKAY 545
H +HRD+K N+L+ G +K+ DFGL AR+ +K
Sbjct: 940 HRMGFIHRDIKPDNILIDRNGHIKLTDFGLCTGFRWTHNSKYYQRDGTHARQDSMEVKCQ 761
Query: 546 T-------------------------PVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFG 580
+V T Y APE+L Y++ D WSVG I
Sbjct: 760 LDEQCQCEILKPLERRRKREQRCLAHSLVGTPNYIAPEVLSRLGGYTSVCDWWSVGVILF 581
Query: 581 ELLTQKPLFPGNSEIDQINKVF 602
E+L P F N+ + KV
Sbjct: 580 EMLVGHPPFYANTPAETQYKVI 515
>30755
Length = 1137
Score = 61.2 bits (147), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 35/94 (37%), Positives = 51/94 (54%), Gaps = 3/94 (3%)
Frame = +2
Query: 496 QLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLARE---YGSPLKAYTPVVVTQ 552
+++ + +LH I++RDLK NLLL G +KV DFGL +E YG K + T
Sbjct: 56 EIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCKEDITYGRTTKTFCG---TP 226
Query: 553 WYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQK 586
Y APE +L +Y AVD W G + E++ +
Sbjct: 227 EYLAPE-VLDDNDYGRAVDWWGTGVVMYEMICGR 325
>13212
Length = 1067
Score = 61.2 bits (147), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 46/206 (22%), Positives = 93/206 (45%), Gaps = 4/206 (1%)
Frame = -1
Query: 474 LKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFG 533
L S+M +++P ++ + ++ + LH + ++HRD+K N+LL+ G +K+ DFG
Sbjct: 1022 LDSIMVDLEKPMTEAQICYVCHEMCMALDFLHRHHVIHRDIKAGNVLLTIDGEVKLADFG 843
Query: 534 LAREYGSPLKAYTPVVVTQWYRAPELLLGA----KEYSTAVDMWSVGCIFGELLTQKPLF 589
++ + + + T ++ APE++L Y D+WS+G E
Sbjct: 842 VSAKNTQTQQKRDTFIGTPYWMAPEVVLCETLKDTPYDFKADIWSLGVTLIE-------- 687
Query: 590 PGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKMTFSEHPYNNLRKRFGALLSDQGFD 649
F ++ P++++ P + V+ K+ S+ P K++ L D
Sbjct: 686 ------------FAQIEPPNKEMHP----MRVLIKIHKSDPPTLEKPKKWTKLFK----D 567
Query: 650 LMNKFLTYFPGRRISAEDGLKHEYFR 675
+ K L P R +A + L+H + +
Sbjct: 566 FIAKCLVKDPNLRPTAAELLEHPFMK 489
>28638
Length = 1458
Score = 60.8 bits (146), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 33/81 (40%), Positives = 51/81 (62%), Gaps = 2/81 (2%)
Frame = -1
Query: 509 ILHRDLKTSNLLLSHA--GILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEY 566
I+H DLK N+LL + +K+ DFG + + G + Y + +++YR+PE+LLG Y
Sbjct: 768 IIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQY---IQSRFYRSPEVLLGVP-Y 601
Query: 567 STAVDMWSVGCIFGELLTQKP 587
A+DMWS+GCI E+ T +P
Sbjct: 600 DLAIDMWSLGCILVEMHTGEP 538
Score = 30.0 bits (66), Expect = 3.9, Method: Compositional matrix adjust.
Identities = 15/52 (28%), Positives = 22/52 (42%), Gaps = 5/52 (9%)
Frame = -2
Query: 566 YSTAVDMWSVGC-----IFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKI 612
Y W + C + PLF G++E DQ+ K+ + LG P I
Sbjct: 617 YXXCPMTWPLTCGXWAVYWWRCTXGNPLFAGSNEFDQMMKIVEVLGVPPRHI 462
>13066
Length = 551
Score = 60.5 bits (145), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 52/188 (27%), Positives = 88/188 (46%), Gaps = 6/188 (3%)
Frame = +3
Query: 395 IEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREI 454
+ GT+ Y K +I+ ++ ++ ++ FP RE++ + K HP I+ + I
Sbjct: 15 VVHGTFNDGYGRNIKLACKIIDKEKAPVDFVEKFFP----RELDLLTKLDHPYIIQIHSI 182
Query: 455 VVGSNMDKIYIVMNYVEH-DLKSLMETMKQPFLP-GEVKTLMIQLLRGVKHLHDNWILHR 512
+ K +I M + E DL + ++ + F+ + K Q+ + +LH + HR
Sbjct: 183 L--QRXPKNFIFMRFAERGDLLTYIQEVG--FVKEKQAKIWFYQMTTALNYLHSYDVAHR 350
Query: 513 DLKTSNLLLSHAGILKVGDFGLA----REYGSPLKAYTPVVVTQWYRAPELLLGAKEYST 568
DLK N+LLS +K+ DFG A E G + T + Y APE++ GA
Sbjct: 351 DLKCENILLSSHFNVKLADFGFACACITESGEKYMSRT-YCGSAAYAAPEIVYGAPYAPK 527
Query: 569 AVDMWSVG 576
D WS+G
Sbjct: 528 VADAWSLG 551
>26909
Length = 394
Score = 60.1 bits (144), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 38/119 (31%), Positives = 57/119 (47%), Gaps = 16/119 (13%)
Frame = +2
Query: 578 IFGELLTQKPLFPGNSEI---------DQINKVFKELGTPSEKIWPGYSELPVVKKMT-- 626
IF ELLT +P+F E DQ++++F +G P EK W +P +++T
Sbjct: 2 IFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFPQEKDWEDIRRMPEHQQLTKD 181
Query: 627 FSEHPYNNLR-----KRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLP 680
F Y N ++ + F L+ K LT P +RI++E +K YF E PLP
Sbjct: 182 FKRSSYVNCNLMKYMEKHKVKADSKAFHLLQKLLTMDPVKRITSEQAMKDPYFLEEPLP 358
>19094
Length = 898
Score = 58.9 bits (141), Expect = 8e-09, Method: Compositional matrix adjust.
Identities = 31/105 (29%), Positives = 58/105 (55%), Gaps = 2/105 (1%)
Frame = +1
Query: 474 LKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFG 533
+ +M + + E+ T++ L+G+ +LH +HRD+K N+LL++ G K+ DFG
Sbjct: 16 VSDIMRLRNKTLVEREIATILYYTLKGL*YLHSRRKIHRDIKAGNILLNNEGHAKLADFG 195
Query: 534 LAREYGSPLKAYTPVVVTQWYRAPELL--LGAKEYSTAVDMWSVG 576
+A + + V+ T ++ APE++ +G Y D+WS+G
Sbjct: 196 VAGQLTDTMAKRNTVIGTPYWMAPEVIQEIG---YDCVADIWSLG 321
>21808
Length = 1011
Score = 58.2 bits (139), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 56/201 (27%), Positives = 96/201 (47%), Gaps = 14/201 (6%)
Frame = +1
Query: 415 VALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDL 474
VA+K LK P L E + K +HP ++ + V + D I+I+ +++
Sbjct: 28 VAIKTLKSGTMD---PKDFLAEAQIMKKLRHPKLIQL--YAVCTQDDPIFIITELMKNG- 189
Query: 475 KSLMETMKQPFLPGEVKTLMI--------QLLRGVKHLHDNWILHRDLKTSNLLLSHAGI 526
SL+E FL G+ + L + Q+ G+ +L +HRDL N+L+S
Sbjct: 190 -SLLE-----FLQGKGRVLKLPALIDIGAQIACGMAYLESQNYIHRDLAARNILVSDNNT 351
Query: 527 LKVGDFGLAR-----EYGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGE 581
+K+ DFGLAR EY + + A P+ +W APE ++ D+WS G + E
Sbjct: 352 VKIADFGLARVIKEDEYEARVGARFPI---KW-TAPE-AANYNRFTIKSDVWSFGILLTE 516
Query: 582 LLTQKPL-FPGNSEIDQINKV 601
+T + +PG + + +++V
Sbjct: 517 TVTYGRVPYPGMTNAEVLHQV 579
>11185
Length = 473
Score = 56.6 bits (135), Expect = 4e-08, Method: Compositional matrix adjust.
Identities = 35/117 (29%), Positives = 56/117 (47%), Gaps = 22/117 (18%)
Frame = +1
Query: 490 VKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAY---- 545
++ I L+ G+ ++H IL DL+ S +LL +G+LK DFGL++ G L+
Sbjct: 7 IRDFGIHLVTGLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKF 186
Query: 546 ------------------TPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLT 584
P + Y APE+ GA E S D+W++GC+F E+ +
Sbjct: 187 AEAGDQWNIQSAEEMMKQVPTSGSPTYMAPEVFQGA-EPSIMSDLWALGCVFYEMFS 354
>19301
Length = 712
Score = 55.8 bits (133), Expect = 6e-08, Method: Compositional matrix adjust.
Identities = 43/149 (28%), Positives = 75/149 (50%), Gaps = 2/149 (1%)
Frame = +2
Query: 387 EEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHP 446
E L + G G V+ K E VA+K+++ KE + I +LR++N HP
Sbjct: 305 ESITDLEWLGSGAQGAVFLGK--LCAEEVAVKKVRDIKETD---IRNLRKLN------HP 451
Query: 447 NIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMK--QPFLPGEVKTLMIQLLRGVKHL 504
NI++ + + + I+M Y + L E ++ + P V Q+ G+ +L
Sbjct: 452 NIISFKGVC--TQAPCYCIIMEYCPY--GQLYEVLRDGKEIPPALVLDWSKQIASGMNYL 619
Query: 505 HDNWILHRDLKTSNLLLSHAGILKVGDFG 533
H + I+HRDLK+ N+L++ ++K+ DFG
Sbjct: 620 HSHKIIHRDLKSPNVLVAKNDVVKISDFG 706
>27405
Length = 532
Score = 55.8 bits (133), Expect = 6e-08, Method: Compositional matrix adjust.
Identities = 28/89 (31%), Positives = 52/89 (58%)
Frame = -3
Query: 485 FLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKA 544
F EV+ +++ G++H+H ++++RDLK +N+LL G +++ D GLA ++ K
Sbjct: 263 FTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGLACDFSK--KK 90
Query: 545 YTPVVVTQWYRAPELLLGAKEYSTAVDMW 573
V T Y APE+L+ + Y ++ D +
Sbjct: 89 PHASVGTHGYMAPEVLMKGQAYDSSADWF 3
>07940
Length = 1336
Score = 55.8 bits (133), Expect = 7e-08, Method: Compositional matrix adjust.
Identities = 35/112 (31%), Positives = 56/112 (50%), Gaps = 6/112 (5%)
Frame = -3
Query: 479 ETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLARE- 537
+ M + P ++ + Q+ RG+++L +HRDL N+L++ +LK+ DFGL R
Sbjct: 374 QDMLKMLTPKDLISYAYQVARGMEYLASKQCIHRDLAARNVLVAEEYVLKIADFGLTRNL 195
Query: 538 -----YGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLT 584
Y PV +W APE L K Y++ D+WS G + E+ T
Sbjct: 194 QQFDYYRKTTDGRLPV---KW-MAPEALFDRK-YTSKSDVWSYGVLLWEIFT 54
>18287
Length = 678
Score = 55.5 bits (132), Expect = 8e-08, Method: Composition-based stats.
Identities = 35/119 (29%), Positives = 53/119 (44%), Gaps = 8/119 (6%)
Frame = -3
Query: 566 YSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKM 625
Y ++D+WSVGCIF ELL+++ LF + Q++ + +GTP + E
Sbjct: 673 YDYSIDIWSVGCIFAELLSRRILFQAQGPVQQLDMIINLVGTPRPEDMERACE------- 515
Query: 626 TFSEHPYNNLRKRFGALL--------SDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 676
H N +R L + + L+ + L P RISAE+ L H Y E
Sbjct: 514 GARNHILNQPFRRQNLLTLYNLSPHATHEAVRLLTRMLILNPKNRISAEEALSHPYLDE 338
>26711
Length = 405
Score = 55.5 bits (132), Expect = 8e-08, Method: Composition-based stats.
Identities = 39/111 (35%), Positives = 61/111 (54%), Gaps = 6/111 (5%)
Frame = -2
Query: 496 QLLRGVKHLHDNWILHRDLKTSNLLLSHAGI--LKVGDFGLAREYGSPLKAY----TPVV 549
Q+L ++H+H ++H DLK SNLLLS + +++ DFGLAR+ P + + TP
Sbjct: 392 QVLDILQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARKLYPPQETFLNHGTP-- 219
Query: 550 VTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINK 600
+ +PE L K STA D+W VG + LL+ + F +S + + K
Sbjct: 218 ---GFTSPE-ALDVKPISTASDVWGVGVLAYILLSGQSPFQADSATESLKK 78
>24241
Length = 413
Score = 55.1 bits (131), Expect = 9e-08, Method: Compositional matrix adjust.
Identities = 25/84 (29%), Positives = 54/84 (64%)
Frame = -2
Query: 392 LNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTV 451
L++I EGTYGVVY+ + + T +A+K++++ ++G P +++REI + + +H +
Sbjct: 328 LSKIGEGTYGVVYKCRHRATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTQXLVC 149
Query: 452 REIVVGSNMDKIYIVMNYVEHDLK 475
E V+ + +++++V ++ DLK
Sbjct: 148 LEDVIMED-ERLFLVFEFLSMDLK 80
>28157
Length = 400
Score = 55.1 bits (131), Expect = 1e-07, Method: Composition-based stats.
Identities = 44/129 (34%), Positives = 67/129 (51%), Gaps = 8/129 (6%)
Frame = +3
Query: 415 VALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSNMDK-IYIVMNYVEHD 473
VA+KR++ E+EK+ F ++E+ + + HPNIV + G+ D + +VM Y E
Sbjct: 9 VAVKRIESEQEKKSF----MQELKQLSRVSHPNIVCL----YGACRDHPVCLVMEYAEGG 164
Query: 474 --LKSLMETMKQP-FLPGEVKTLMIQLLRGVKHLHD---NWILHRDLKTSNLLLSHAGI- 526
L + QP + ++Q GV++LH ++HRDLK NLLL G
Sbjct: 165 SLYNVLHGSGPQPQYTAAHAMNWLLQCALGVEYLHGMKPKALIHRDLKPPNLLLIQCGTK 344
Query: 527 LKVGDFGLA 535
LK+ DFG A
Sbjct: 345 LKICDFGTA 371
>31489
Length = 329
Score = 54.7 bits (130), Expect = 1e-07, Method: Composition-based stats.
Identities = 28/81 (34%), Positives = 50/81 (61%), Gaps = 4/81 (4%)
Frame = +3
Query: 444 QHPNIVTVREIVVGSN----MDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLR 499
+H NI+++REI+ + I++V + +E DL ++ + QP ++ + Q+LR
Sbjct: 24 KHDNIISIREILKPKDSYHDFKDIHVVFDLMESDLHRIIYS-DQPLTEEHIRYFLYQILR 200
Query: 500 GVKHLHDNWILHRDLKTSNLL 520
G+K++H ++HRDLK SNLL
Sbjct: 201 GLKYIHSANVVHRDLKPSNLL 263
>12672
Length = 773
Score = 53.5 bits (127), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 31/89 (34%), Positives = 50/89 (56%), Gaps = 4/89 (4%)
Frame = +3
Query: 500 GVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREY----GSPLKAYTPVVVTQWYR 555
G+++L+DN +HRD+KT+N+LL KVGDF G ++ + V+ T Y
Sbjct: 27 GIQYLNDNGHVHRDIKTANILLDSEYTAKVGDFATVVSAPSGEGKTVQNASVVIGTAAYL 206
Query: 556 APELLLGAKEYSTAVDMWSVGCIFGELLT 584
APE + + ST +D +S G + E++T
Sbjct: 207 APEAI--HFDVSTKLDSYSFGVVLLEVIT 287
>17253
Length = 483
Score = 53.1 bits (126), Expect = 4e-07, Method: Composition-based stats.
Identities = 44/140 (31%), Positives = 67/140 (47%), Gaps = 14/140 (10%)
Frame = -1
Query: 423 EKEKEGFPITSLREINTILK-AQHPNIVTVREIVVGSNMDKIYIVMNYVEH-DLKSLMET 480
+ EK F LRE++ + K +HPN+V+ S D I+M + H DL S +
Sbjct: 426 DAEKSEF----LRELSIMRKLPRHPNVVSFMGCCTMS--DPALILMEFCCHGDLLSFLRK 265
Query: 481 MKQP----FLPGEVKTLM--------IQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILK 528
++P FL L + + RG+ H+ +N I+HRD+ N+L+S + K
Sbjct: 264 -RRPDRTVFLTSTANDLTARDFFSFALHVARGMAHVANNKIVHRDVAARNVLISERNVCK 88
Query: 529 VGDFGLAREYGSPLKAYTPV 548
V DFGL+R G Y V
Sbjct: 87 VSDFGLSRRVGDQNDVYEIV 28
>04852
Length = 1462
Score = 52.8 bits (125), Expect = 5e-07, Method: Compositional matrix adjust.
Identities = 30/90 (33%), Positives = 48/90 (53%)
Frame = +1
Query: 495 IQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWY 554
Q+ RG++ L +HRDL N+L++ +LK+ DFGL+R K + +W
Sbjct: 346 FQIARGMEFLASRKCIHRDLAARNVLVTEEHVLKIADFGLSRTGDYYKKRSGGRLPVKWM 525
Query: 555 RAPELLLGAKEYSTAVDMWSVGCIFGELLT 584
APE L + Y+T D+WS G + E+ +
Sbjct: 526 -APEALFDMR-YTTKSDVWSFGVVLWEIFS 609
>00715
Length = 1788
Score = 52.0 bits (123), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 48/177 (27%), Positives = 84/177 (47%), Gaps = 29/177 (16%)
Frame = +1
Query: 444 QHPNIVTVREIVVGSNM-----DKIYIVMNYV-EHDLKSLMETMKQPFLPGEVKTLMIQL 497
+H N+V++ +G+ D ++ M YV +L++++ +Q +L +Q+
Sbjct: 100 RHVNVVSI----LGATSLHRFEDGAWLAMEYVGPLNLQTILNDHQQDIDSSMRLSLALQM 267
Query: 498 LRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREY---------------GSPL 542
RG+ +LH I+H DLK +N LL+ L++ DFG + G+ L
Sbjct: 268 ARGLHYLHSINIVHLDLKPANCLLTRDLKLRIADFGCCHQLTPTGLDMGEREGGMAGNEL 447
Query: 543 KAYTPV--------VVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPG 591
+ TPV T YRAPELL G + S D++S+G ++ T++ + G
Sbjct: 448 E-LTPVQGAWKNELAGTLAYRAPELLKGLQP-SVRSDVYSLGITLWQMCTRQGPYEG 612
>18401
Length = 463
Score = 51.6 bits (122), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 39/144 (27%), Positives = 66/144 (45%), Gaps = 14/144 (9%)
Frame = -3
Query: 545 YTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKE 604
++ +V T+ YRAPE++L +S D+WSVGCI EL T LF + + + + +
Sbjct: 461 HSTIVSTRHYRAPEVILELG-WSHPCDVWSVGCIMFELYTGYTLFQTHDNKEHLAMMERI 285
Query: 605 LGTPSEKI--------WPGYSELPVVKKMTFSEHPYNNLRKRFGALLS------DQGFDL 650
LG+ ++ + + L V ++ + + + N + + Q FDL
Sbjct: 284 LGSLPYRMAKKTKKQKYFHHGRLDVPERSSMARYVRENTKPLLRYVKDRENKDHQQLFDL 105
Query: 651 MNKFLTYFPGRRISAEDGLKHEYF 674
M K L Y R S L+H +F
Sbjct: 104 MKKLLAYEASSRYSLLQALQHPFF 33
>21079
Length = 878
Score = 50.8 bits (120), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 34/91 (37%), Positives = 50/91 (54%), Gaps = 2/91 (2%)
Frame = +1
Query: 496 QLLRGVKHLHDNWILHRDLKTSNLLL--SHAGILKVGDFGLAREYGSPLKAYTPVVVTQW 553
Q+ GV ++H ILH DLK N+L ++ +K+ DFGLAR Y P + + T
Sbjct: 151 QICSGVGYMHTQSILHLDLKPENVLCVSDNSNQIKIIDFGLARFY-KPGDSLQVLFGTPE 327
Query: 554 YRAPELLLGAKEYSTAVDMWSVGCIFGELLT 584
+ APE ++ E + DMWS+G I LL+
Sbjct: 328 FIAPE-VVNYDEINFTTDMWSIGVICYILLS 417
>16003
Length = 926
Score = 50.8 bits (120), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 35/99 (35%), Positives = 51/99 (51%)
Frame = -1
Query: 582 LLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKMTFSEHPYNNLRKRFGA 641
LL + P PG++++DQ+ K+F LGTP+E WP + LP + F L++ F A
Sbjct: 926 LLIRLPFLPGDTDLDQLGKIFNMLGTPTETEWPAVTSLP--DYIQFKHCQKQPLKEIFTA 753
Query: 642 LLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLP 680
D +L++K L P R +A LK YF P P
Sbjct: 752 -AGDDLLELLDKLLAMNPLHRCTATQALKMPYFSNKPYP 639
>00392
Length = 668
Score = 50.1 bits (118), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 46/163 (28%), Positives = 74/163 (45%), Gaps = 6/163 (3%)
Frame = +3
Query: 444 QHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTL---MIQLLRG 500
QHPNIV + N +++ E ++T + F VK L Q+L+G
Sbjct: 105 QHPNIVRFFDYWEEHNHRNRKVIILVTELMTSGTLKTYLKRFKKPNVKILKNWCRQVLKG 284
Query: 501 VKHLHDNW--ILHRDLKTSNLLLSH-AGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAP 557
+ LH ++HRDLK N+ ++ G +K+GD GLA V+ T + AP
Sbjct: 285 LYFLHTRTPPVIHRDLKCDNIFITGPTGSVKIGDLGLATLKNQSFAK--SVIGTPEFMAP 458
Query: 558 ELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINK 600
E+ + Y AVD+++ G E+ + + + S QI K
Sbjct: 459 EMY--EEHYDEAVDVYAFGMCMLEMASSEYPYSECSNAAQIYK 581
>12786
Length = 460
Score = 50.1 bits (118), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 38/117 (32%), Positives = 58/117 (49%), Gaps = 23/117 (19%)
Frame = -3
Query: 496 QLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLA----REYGSPLKAYTPVVVT 551
++LR VK LH+ ++H DLK +N +L AG LK+ DFG+A ++ S LK V T
Sbjct: 386 EMLRAVKALHNEGVIHSDLKPANFMLV-AGNLKLIDFGIANTLQQDKTSVLK--DSRVGT 216
Query: 552 QWYRAPELLLGAKE-----------------YSTAV--DMWSVGCIFGELLTQKPLF 589
Y +PE ++ A + Y V D+WS+GCI ++ + F
Sbjct: 215 PSYMSPEAIMAACDDSADDSMEEDGHRTKPKYKVGVRSDVWSLGCILYNMVYGRTPF 45
>17300
Length = 480
Score = 49.7 bits (117), Expect = 4e-06, Method: Composition-based stats.
Identities = 31/90 (34%), Positives = 51/90 (56%), Gaps = 5/90 (5%)
Frame = +1
Query: 500 GVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLK--AYTP---VVVTQWY 554
G+ L D +HRDL N+L++ + KV DFGL+RE S AYT + +W
Sbjct: 10 GMGXLADMGYVHRDLAARNILVNEILVCKVADFGLSREIESDTTEGAYTTKGGKIPVRW- 186
Query: 555 RAPELLLGAKEYSTAVDMWSVGCIFGELLT 584
APE + +++++A D+WS G + E+++
Sbjct: 187 TAPE-AIAYRKFTSASDVWSFGVVMWEVMS 273
>31885
Length = 529
Score = 47.4 bits (111), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 46/161 (28%), Positives = 73/161 (45%), Gaps = 4/161 (2%)
Frame = -2
Query: 437 INTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQ 496
++ + + HP +V + D +V ++ DL+ M+ + F VK + Q
Sbjct: 519 VDMLTRLDHPFLVNLW-YAFQDEEDLFMVVDLFLGGDLRYHMQQ-EVSFREDCVKFYLCQ 346
Query: 497 LLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRA 556
L + +L I+HRD+K N+LL G V DF +A + A T T+ Y A
Sbjct: 345 LALVLDYLRSQKIVHRDIKPDNILLDEQGHCHVTDFNIATQLEDDELA-TSTSGTRPYMA 169
Query: 557 PELLLGA----KEYSTAVDMWSVGCIFGELLTQKPLFPGNS 593
PE+ A + Y VD WS+G ELL ++ F +S
Sbjct: 168 PEVYGVAINERRGYGFPVDWWSLGVSLFELLKKRRPFSVHS 46
>11780
Length = 1713
Score = 46.2 bits (108), Expect = 5e-05, Method: Compositional matrix adjust.
Identities = 51/202 (25%), Positives = 98/202 (48%), Gaps = 4/202 (1%)
Frame = +3
Query: 395 IEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREI 454
I +G +G VY+ + + VA+K+LK +K+ + L+E + + +H N+V + +
Sbjct: 621 IGKGDFGDVYKGMYR--GQPVAIKQLK---DKDRGEQSFLQEASVMTSLRHDNLVRLIGV 785
Query: 455 VVGSNMDKIYIVMNYV-EHDLKSLMETMKQPFLPGEVK-TLMIQLLRGVKHLHDNWILHR 512
V+G + I++V ++ + +L + + + + + + +++L ++HR
Sbjct: 786 VLG---ETIFLVTEFMGKGNLVEYLRSRGRSVITKKDQINFATDTCAAMEYLESKRLVHR 956
Query: 513 DLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEY--STAV 570
DL N+L+ G KV DFGLA+ +G + T V + APE L K + V
Sbjct: 957 DLAARNVLVHDDGKAKVSDFGLAK-FGDF--SQTSVKFPIKWTAPEALRENKIH*QVRHV 1127
Query: 571 DMWSVGCIFGELLTQKPLFPGN 592
++W + + G LL P N
Sbjct: 1128ELWHI--VMGNLLLWSSALP*N 1187
>05084
Length = 1324
Score = 45.1 bits (105), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 28/92 (30%), Positives = 43/92 (46%), Gaps = 4/92 (4%)
Frame = +2
Query: 589 FPGNSEIDQINKVFKELGTPS----EKIWPGYSELPVVKKMTFSEHPYNNLRKRFGALLS 644
PG+S +DQ+ ++ K LGTP+ ++ P YSE K HP+ K F
Sbjct: 2 LPGDSGVDQLVEIIKVLGTPTREQIREMNPNYSEF---KFPQIKAHPWT---KVFRPRTP 163
Query: 645 DQGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 676
+ L+++ L Y P RI + H +F E
Sbjct: 164 PEAIQLVSRLLEYTPSARIQPMEACAHAFFDE 259
>20640
Length = 1492
Score = 44.3 bits (103), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 26/79 (32%), Positives = 40/79 (50%), Gaps = 4/79 (5%)
Frame = +1
Query: 510 LHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYT----PVVVTQWYRAPELLLGAKE 565
+HRDL T N L+ H ++K+ DFGLAR S + Y + +W +L +
Sbjct: 10 VHRDLATRNCLVGHDLVVKISDFGLARSVHS-VDYYRGSEHDAIPIRWMPLEAILYN--K 180
Query: 566 YSTAVDMWSVGCIFGELLT 584
+ST D+WS G + E+
Sbjct: 181 FSTQSDVWSFGVVLWEIFA 237
>07836
Length = 1478
Score = 43.5 bits (101), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 53/190 (27%), Positives = 85/190 (44%), Gaps = 20/190 (10%)
Frame = -1
Query: 413 EIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIV--TVREIVVGSNMDKIYIVMNYV 470
E VA+K +E F T L + T+L +H NI+ +I + +++++ +Y
Sbjct: 1475 ENVAVKIFFTTEEASWFRETELYQ--TVL-LRHENILGFIAADIKGTGSWTQLFLITDY- 1308
Query: 471 EHDLKSLMETMKQPFL-PGEVKTLMIQLLRGVKHLHDNW--------ILHRDLKTSNLLL 521
H+ SL + + L E+ L + G+ HLH I HRD+K+ N+L+
Sbjct: 1307 -HENGSLHDYLLSRVLDSSEMLALAHSAICGLAHLHIEIFGTRGKPAIAHRDIKSKNILV 1131
Query: 522 SHAGILKVGDFGLAREYGSPLK----AYTPVVVTQWYRAP---ELLLGAKEYST--AVDM 572
G + D GLA Y S A P T+ Y AP E+LL K + DM
Sbjct: 1130 KKNGTCCIADLGLAVRYISESNEVDVAPNPRQGTKRYMAPEVLEMLLNVKNFDAFKQADM 951
Query: 573 WSVGCIFGEL 582
++ G + E+
Sbjct: 950 YAFGLVMWEI 921
>17975
Length = 449
Score = 43.5 bits (101), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 35/146 (23%), Positives = 67/146 (45%), Gaps = 10/146 (6%)
Frame = +3
Query: 400 YGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSN 459
+ VV A+ T E VA+K + K E +E+ + QHPN+V + E++
Sbjct: 6 FAVVKLARHVFTGEKVAVKVIDKTKLDEVSRSHLFQEVRCMKLVQHPNVVRLYEVI--DT 179
Query: 460 MDKIYIVM---------NYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWIL 510
K+Y+++ +Y+ L E + + + Q++ + + H ++
Sbjct: 180 QTKLYLILELGDGGDMYDYIMRHSGGLEEKLAKRYFR--------QIVEAISYCHKLHVV 335
Query: 511 HRDLKTSNLLLSHA-GILKVGDFGLA 535
HRDLK N++ G++K+ DFG +
Sbjct: 336 HRDLKPENVVFFEKPGLVKLTDFGFS 413
>21433
Length = 590
Score = 42.0 bits (97), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 33/94 (35%), Positives = 50/94 (53%)
Frame = +2
Query: 494 MIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQW 553
+ QL +++ H ++HRD+K NLLL G LK+ DFG + +P T + T
Sbjct: 185 IYQLSSALEYCHYRKVIHRDIKPENLLLGLKGDLKIADFGWSVH--APSSRRTTMCGTLD 358
Query: 554 YRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKP 587
Y PE++ G K + VD+WS+G + E L P
Sbjct: 359 YLPPEMVEG-KTHDENVDLWSLGVLCYEFLVGTP 457
>07291
Length = 833
Score = 41.6 bits (96), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 28/96 (29%), Positives = 50/96 (52%), Gaps = 6/96 (6%)
Frame = +1
Query: 496 QLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGS--PLKAYT----PVV 549
Q+ G+ +L + ++HR+L N +++ G L++ D+G+ GS P YT P
Sbjct: 73 QIADGMAYLQEVKVVHRNLAARNCIVTEDGRLQLSDYGVT---GSLFPQSYYTADDSPAR 243
Query: 550 VTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQ 585
+ APE + +S+ D+W+ G + ELLT+
Sbjct: 244 DLVKWMAPE-TIDNFHFSSKSDVWAFGVVLWELLTR 348
>15549
Length = 470
Score = 40.4 bits (93), Expect = 0.002, Method: Composition-based stats.
Identities = 18/54 (33%), Positives = 35/54 (64%), Gaps = 1/54 (1%)
Frame = -1
Query: 373 LPKYLPALQ-GCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKE 425
LP P+ + R +EF+C+ ++ +G YG+V+RAK+K ++ A+KR+ + +
Sbjct: 263 LPDKAPSAEFKSRFADEFECIEQMGKGGYGIVFRAKNKVDEQEYAVKRIALPSD 102
>02638
Length = 1490
Score = 39.3 bits (90), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 18/50 (36%), Positives = 30/50 (60%)
Frame = +1
Query: 554 YRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFK 603
+ APE+L G + Y A D+WSVGC+ E+ T +P + + + + +FK
Sbjct: 34 FMAPEVLRG-ESYGRACDVWSVGCVMIEMCTCRPPWNSHDISNHLALIFK 180
>14477
Length = 493
Score = 39.3 bits (90), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 41/147 (27%), Positives = 70/147 (47%), Gaps = 4/147 (2%)
Frame = -1
Query: 394 RIEEGTYGVVYRAKDKKTD-EI-VALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTV 451
++ G +G V + + D EI VA+K LK ++E + K H +IV +
Sbjct: 469 KLGAGNFGSVMKGVCRLDDREIPVAIKVLKNADLDPSVQSELIKEAEVMKKMDHMHIVRL 290
Query: 452 REIVVGSNMDKIYIVMNYVEHDLKSLMETM-KQPFLP-GEVKTLMIQLLRGVKHLHDNWI 509
+ G M +V+ + L L + + K LP + LM Q+ +G+++L N
Sbjct: 289 IGLCEGETM---MLVLELAK--LGPLNKFLPKNKHLPLWNILELMWQVSQGMEYLEANKF 125
Query: 510 LHRDLKTSNLLLSHAGILKVGDFGLAR 536
+HRDL N+LL K+ DFG+++
Sbjct: 124 VHRDLAARNILLCDEHFAKISDFGMSK 44
>37602
Length = 804
Score = 38.9 bits (89), Expect = 0.008, Method: Compositional matrix adjust.
Identities = 20/72 (27%), Positives = 39/72 (54%)
Frame = -1
Query: 461 DKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLL 520
+K++I M Y + + P ++ + + L+G+ +LH +HRD+K +N+L
Sbjct: 300 EKLWIAMEYCGGGSMQDIYHVTGPLTEPQIAFVCRETLKGLHYLHRRGKMHRDIKGANIL 121
Query: 521 LSHAGILKVGDF 532
L+ G +K+ DF
Sbjct: 120 LTEEGDVKLADF 85
Score = 28.9 bits (63), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 13/36 (36%), Positives = 21/36 (58%)
Frame = -2
Query: 372 ELPKYLPALQGCRSVEEFQCLNRIEEGTYGVVYRAK 407
E K +Q +++F+ + R+ GTYG VY+AK
Sbjct: 554 EYKKMQADIQRRNPLDDFELIQRVGSGTYGDVYKAK 447
>16708
Length = 1397
Score = 38.9 bits (89), Expect = 0.008, Method: Compositional matrix adjust.
Identities = 16/52 (30%), Positives = 31/52 (59%)
Frame = -1
Query: 487 PGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREY 538
P V + Q + ++H+H+ ++H D+K N+L+ G K+ D+G+A+ Y
Sbjct: 1097 PAMVCCIAGQXVCALEHIHELGVVHMDVKADNVLVDAHGNCKLTDYGIAQLY 942
>26009
Length = 886
Score = 32.0 bits (71), Expect(2) = 0.008, Method: Compositional matrix adjust.
Identities = 12/33 (36%), Positives = 22/33 (66%)
Frame = +3
Query: 489 EVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLL 521
E K++M QL+ + +H ++HRD+K N+L+
Sbjct: 714 EAKSVMKQLVSALDFMHSKQLVHRDIKPENVLI 812
Score = 25.4 bits (54), Expect(2) = 0.008, Method: Compositional matrix adjust.
Identities = 23/93 (24%), Positives = 35/93 (37%), Gaps = 5/93 (5%)
Frame = +2
Query: 387 EEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREIN-----TIL 441
E + + GTYG V A+ + T VALK L T LRE +
Sbjct: 416 EHYDVCKELGRGTYGKVVLARCRHTGTQVALKLLPKS-------CTKLREFQREFQLSYF 574
Query: 442 KAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDL 474
+ H NI+ + + ++ + V DL
Sbjct: 575 LSPHANIIDTYNVAFQTRSSYVFAQEHAVLGDL 673
>13078
Length = 773
Score = 38.1 bits (87), Expect = 0.012, Method: Compositional matrix adjust.
Identities = 31/125 (24%), Positives = 59/125 (47%), Gaps = 14/125 (11%)
Frame = -1
Query: 566 YSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKI--------WPGYS 617
+S D+WS+GCI EL T LF + + + + + LG+ ++ + +
Sbjct: 746 WSQPCDVWSIGCIMFELYTGYTLFQTHDNKEHLAMMERILGSLPYRMAKKTKKQKYFYHG 567
Query: 618 ELPVVKKMTFSEHPYNNLR--KRFGALLSD----QGFDLMNKFLTYFPGRRISAEDGLKH 671
L +K + + +N++ +R+ + Q FDLM+K L+Y R S ++H
Sbjct: 566 RLDWDEKSSAGRYVRDNVKPLRRYVKDPDNEDHQQLFDLMDKMLSYEVSTRYSLRQAMRH 387
Query: 672 EYFRE 676
+FR+
Sbjct: 386 PFFRK 372
>18481
Length = 437
Score = 38.1 bits (87), Expect = 0.013, Method: Compositional matrix adjust.
Identities = 24/77 (31%), Positives = 38/77 (49%), Gaps = 3/77 (3%)
Frame = -1
Query: 465 IVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLS-- 522
+VM + L+ L K+ F + + QLL ++ +H +HRDLK N L+
Sbjct: 266 LVMELLGPSLEELFVICKRRFTLKTILMVSDQLLSRLEFIHQKCFIHRDLKPDNFLMGLG 87
Query: 523 -HAGILKVGDFGLAREY 538
H L + DFGL++ Y
Sbjct: 86 RHCHRLYIIDFGLSKRY 36
>00486
Length = 797
Score = 35.4 bits (80), Expect = 0.079, Method: Compositional matrix adjust.
Identities = 18/50 (36%), Positives = 27/50 (54%)
Frame = -2
Query: 554 YRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFK 603
Y APE+L + AVD WS+G + ++LT P F + I+K+ K
Sbjct: 760 YMAPEILTRTG-HGKAVDWWSLGALMYDMLTGSPPFTAENRKKTIDKILK 614
>36481
Length = 806
Score = 33.1 bits (74), Expect = 0.38, Method: Compositional matrix adjust.
Identities = 37/149 (24%), Positives = 66/149 (44%), Gaps = 6/149 (4%)
Frame = +2
Query: 379 ALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLK-MEKEKEGFPITSLREI 437
++G S + + EGT+G V + KD + +ALK +K ++K +E + EI
Sbjct: 338 TMRGTSSTNDMKLCPHWGEGTFGKVVQCKDLLKGDDIALKIIKNVDKYREAAKL----EI 505
Query: 438 NTILKAQ----HPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGE-VKT 492
N + K + H + V+ + + I + + + ++ P E V+
Sbjct: 506 NVLEKLREKDPHAKHMCVQMLDWFDYHGHVCISFHMLGLSVFDFLKDNSYGAYPIEQVRH 685
Query: 493 LMIQLLRGVKHLHDNWILHRDLKTSNLLL 521
+ QL V LH+N + H DLK N+L
Sbjct: 686 ISYQLCYAVNFLHENQLTHTDLKPENILF 772
>00145
Length = 2325
Score = 30.8 bits (68), Expect = 1.9, Method: Compositional matrix adjust.
Identities = 18/50 (36%), Positives = 25/50 (50%), Gaps = 1/50 (2%)
Frame = -1
Query: 655 LTYFPGRRISAEDGLKHEYFRETP-LPIDPSMFPTWPAKSEQQRVKRGTS 703
+ P RIS DG + RE+P LP D + P P + Q+ V R T+
Sbjct: 2325 IQVHPQHRISQSDGESVDVQRESPLLPRDGAAVPQRPGPAAQEGVSRQTA 2176
>15931
Length = 447
Score = 30.4 bits (67), Expect = 2.5, Method: Compositional matrix adjust.
Identities = 13/31 (41%), Positives = 19/31 (61%)
Frame = +1
Query: 646 QGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 676
Q FDLM+K L+Y R S ++H +FR+
Sbjct: 70 QLFDLMDKMLSYEVSTRYSLRQAMRHPFFRK 162
>20152
Length = 445
Score = 30.0 bits (66), Expect = 3.6, Method: Compositional matrix adjust.
Identities = 14/33 (42%), Positives = 20/33 (60%)
Frame = +1
Query: 557 PELLLGAKEYSTAVDMWSVGCIFGELLTQKPLF 589
PE+LLG + AVD+WS+G I L+ + F
Sbjct: 1 PEILLGDSYDAPAVDVWSLGVILYMLVVGEAPF 99
>38560
Length = 479
Score = 29.3 bits (64), Expect = 6.2, Method: Composition-based stats.
Identities = 12/30 (40%), Positives = 18/30 (60%)
Frame = -3
Query: 554 YRAPELLLGAKEYSTAVDMWSVGCIFGELL 583
Y APEL+ G + + D+WS+G + LL
Sbjct: 387 YAAPELISGLEYLGSEADIWSMGVLLYALL 298
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000352721 | hsapiens_gene_ensembl | Dynamin-2 (EC
3.6.5.5). [Source:Uniprot/SWISSPROT;Acc:P50570]
(866 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
29522 307 1e-83
38072 96 4e-38
13952 35 0.15
14762 32 1.0
15376 32 1.3
>29522
Length = 698
Score = 307 bits (786), Expect = 1e-83, Method: Compositional matrix adjust.
Identities = 141/206 (68%), Positives = 173/206 (83%)
Frame = -3
Query: 344 IEGSGDQVDTLELSGGARINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLF 403
IEG G QV T +LSGGA+INRIFHERFPFELVKMEFDE++LR+EI I+NIHG+RTGLF
Sbjct: 696 IEGFGAQVSTEDLSGGAKINRIFHERFPFELVKMEFDERELRKEIGITIRNIHGIRTGLF 517
Query: 404 TPDLAFEAIVKKQVVKLKEPCLKCVDLVIQELINTVRQCTSKLSSYPRLREETERIVTTY 463
TPD+AFE+IV KQ+ +LKEP L CVDLVI EL VR+ K+S YPRLREETERIV +
Sbjct: 516 TPDMAFESIVVKQIERLKEPSLHCVDLVITELSQVVRKAGEKMSRYPRLREETERIVNSR 337
Query: 464 IREREGRTKDQILLLIDIEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQVIRRGWLT 523
IRE+E R K+QIL LID + +Y+NTNHEDFIGF+NAQQ++ + KR + NQVIR+GWL+
Sbjct: 336 IREQEQRAKEQILTLIDFQLAYMNTNHEDFIGFSNAQQKAESQSSKRKMGNQVIRKGWLS 157
Query: 524 INNISLMKGGSKEYWFVLTAESLSWY 549
++NIS +KGGSK++WFVLTAESLSW+
Sbjct: 156 LHNISFIKGGSKDFWFVLTAESLSWF 79
>38072
Length = 513
Score = 96.3 bits (238), Expect(2) = 4e-38, Method: Compositional matrix adjust.
Identities = 48/78 (61%), Positives = 60/78 (76%)
Frame = -3
Query: 607 EDVDSWKASFLRAGVYPEKDQAENEDGAQENTFSMDPQLERQVETIRNLVDSYVAIINKS 666
EDVDSWKASFLRAGVYPE+ E+ + + PQLERQVETIRNLVDSY+ I+NK+
Sbjct: 511 EDVDSWKASFLRAGVYPERSSDESSSSKDDYSSMD-PQLERQVETIRNLVDSYMKIVNKT 335
Query: 667 IRDLMPKTIMHLMINNTK 684
RDL+PKTIMH+++ +
Sbjct: 334 QRDLIPKTIMHIIVKKCE 281
Score = 81.3 bits (199), Expect(2) = 4e-38, Method: Compositional matrix adjust.
Identities = 42/86 (48%), Positives = 56/86 (65%)
Frame = -1
Query: 682 NTKAFIHHELLAYLYSSADQSSLMEESADQAQRRDDMLRMYHALKEALNIIGDIXXXXXX 741
N K+FI +LLA+LYS+ DQS++MEES ++AQRRD++LRMYHA +EAL II DI
Sbjct: 288 NVKSFIGSDLLAHLYSN-DQSAMMEESQEEAQRRDEILRMYHATREALTIISDISTTTVS 112
Query: 742 XXXXXXXDDTWLQSASSHSPTPQRRP 767
D WL+ +S +P R P
Sbjct: 111 TPTPPPVKDDWLEPSSGSTPYNGRPP 34
>13952
Length = 577
Score = 35.0 bits (79), Expect = 0.15, Method: Compositional matrix adjust.
Identities = 30/123 (24%), Positives = 59/123 (47%), Gaps = 18/123 (14%)
Frame = -3
Query: 517 IRRGWLTINNISLMKGGS----KEYWFVLTAESLSWYXXXXXXXXXYMLPLDNLKIRDV- 571
++ GWL + +GG K WF+L L ++ ++PL+N+++R++
Sbjct: 419 VKEGWL------MKQGGRYKNWKRRWFILNDNCLYYFQYTADKEPKGIIPLENIQVRELS 258
Query: 572 EKGFMSNKHVFAIFNTEQRNVYK------DLRQIE-------LACDSQEDVDSWKASFLR 618
EK SN F +++ +V K D + +E ++ S E++D+W +S +R
Sbjct: 257 EKSSRSN--AFELYSVSGSDVIKACKVDSDGKVVEGRHSVYRMSASSAEEMDAWISS-IR 87
Query: 619 AGV 621
G+
Sbjct: 86 YGI 78
>14762
Length = 1307
Score = 32.0 bits (71), Expect = 1.0, Method: Composition-based stats.
Identities = 16/36 (44%), Positives = 21/36 (58%)
Frame = +2
Query: 635 QENTFSMDPQLERQVETIRNLVDSYVAIINKSIRDL 670
Q+NT S PQ ERQV R L SY ++++ R L
Sbjct: 1151 QQNTASHAPQQERQVTVQRTLTPSYACKVSRAYRAL 1258
>15376
Length = 712
Score = 31.6 bits (70), Expect = 1.3, Method: Composition-based stats.
Identities = 22/92 (23%), Positives = 45/92 (48%), Gaps = 14/92 (15%)
Frame = +1
Query: 538 WFVLTAESLSWYXXXXXXXXXYMLPLDNLKIRDV-EKGFMSNKHVFAIFNTEQRNVYK-- 594
WF+L L ++ ++PL+N+++R++ EK SN F +++ +V K
Sbjct: 4 WFILNDNCLYYFQYTADKEPKGIIPLENIQVRELSEKSSRSN--AFELYSVSGSDVIKAC 177
Query: 595 ----DLRQIE-------LACDSQEDVDSWKAS 615
D + +E ++ S E++D+W +S
Sbjct: 178 KVDSDGKVVEGRHSVYRMSASSAEEMDAWISS 273
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000350950 | hsapiens_gene_ensembl | 26S proteasome
non-ATPase regulatory subunit 2 (26S proteasome regulatory subunit
RPN1) (26S proteasome regulatory subunit S2) (26S proteasome subunit
p97) (Tumor necrosis factor type 1 receptor- associated protein 2)
(55.11 protein). [Source:Uniprot/SWISSPROT;Acc:Q13200]
(580 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
05545 248 3e-83
05493 72 1e-14
32303 29 0.013
24792 30 2.7
>05545
Length = 1952
Score = 248 bits (632), Expect(2) = 3e-83, Method: Compositional matrix adjust.
Identities = 126/197 (63%), Positives = 145/197 (73%), Gaps = 2/197 (1%)
Frame = -1
Query: 319 DMGAHQGVAVLG-PLLLWGRRLVQRWHYEPY-HQLRYGEPTLRRAVPLALALISVSNPRL 376
D+ QG+AVLG L+ G + Y + H LRYGE +RRAVPLALALISVSNP+L
Sbjct: 1790 DLSLQQGIAVLGIGLIAMGEEIGSEMSYRSFGHLLRYGELPIRRAVPLALALISVSNPKL 1611
Query: 377 NILDTLSKFSHDADPEVSYNSIFAMGMVGSGTNNXXXXXXXXXXXXYHAKDPNNLFMVRL 436
ILDTLSKFSHD+DPEV++N+I AMG+VG+GTNN YHAKDPNNLF+VRL
Sbjct: 1610 QILDTLSKFSHDSDPEVAHNAIMAMGIVGAGTNNARLAAMLRQLAVYHAKDPNNLFIVRL 1431
Query: 437 AQXXXXXXXXXXXXCPYHSDRQLMSQVAVAGLLTVLVSFLDVRNIILGKSHYVLYGLVAA 496
AQ CP+HSDR LMS VAVAGL+ L+S LDV+N+ILGKSHYVLY LVAA
Sbjct: 1430 AQGLTHLGKGTLTLCPFHSDRTLMSPVAVAGLMATLISCLDVKNLILGKSHYVLYNLVAA 1251
Query: 497 MQPRMLVTFDEELRPLP 513
MQPRMLVTFDEELRPLP
Sbjct: 1250 MQPRMLVTFDEELRPLP 1200
Score = 79.7 bits (195), Expect(2) = 3e-83, Method: Compositional matrix adjust.
Identities = 37/44 (84%), Positives = 41/44 (93%)
Frame = -2
Query: 530 KPKTITGFQTHTTPVLLAHGERAELATEEFLPVTPILEGFVFGR 573
KPKTITGFQTHTTPVLLA+GERAELATEE+L +TPI+EGFV R
Sbjct: 1150 KPKTITGFQTHTTPVLLAYGERAELATEEYLTLTPIMEGFVILR 1019
>05493
Length = 1292
Score = 72.4 bits (176), Expect(2) = 1e-14, Method: Compositional matrix adjust.
Identities = 34/42 (80%), Positives = 37/42 (88%)
Frame = -3
Query: 62 DKLLTDDGNKWLYKNKDHGMLSAAASLGMILLWDVDGGLTQI 103
DKLL +DGNKWLYKNK+HGMLSA ASLG+ILLW VD GL QI
Sbjct: 147 DKLLMEDGNKWLYKNKEHGMLSATASLGLILLWXVDXGLIQI 22
Score = 25.4 bits (54), Expect(2) = 1e-14, Method: Compositional matrix adjust.
Identities = 9/17 (52%), Positives = 13/17 (76%)
Frame = -1
Query: 41 GLCPHEPGLLFCEWLCE 57
GLC +PGL+ C+ +CE
Sbjct: 215 GLCATKPGLVICQRVCE 165
>32303
Length = 1266
Score = 28.9 bits (63), Expect(2) = 0.013, Method: Compositional matrix adjust.
Identities = 19/58 (32%), Positives = 32/58 (55%), Gaps = 1/58 (1%)
Frame = -2
Query: 147 NSNTMRLGSIFGLGLAYAGSNREDVL-TLLLPVMGDSKSSMEVAGVTALACGMIAVGS 203
+++ +R G GLGLA G+ R+D+ L + D + E AG LA G++ +G+
Sbjct: 1079 STDMVRHGGCLGLGLAAMGTARQDIYEQLKFNLYQDDAVTGEAAG---LAMGLVMLGT 915
Score = 27.7 bits (60), Expect(2) = 0.013, Method: Compositional matrix adjust.
Identities = 17/69 (24%), Positives = 27/69 (39%)
Frame = -3
Query: 221 ETELKDTYARWLPLGLGLNHLGKGXXXXXXXXXXXVVSEPFRSFANTLVDVCAYAGSGNV 280
T + R L +G+ L G+ +P +A AY GSGN
Sbjct: 874 RTTQHEKILRGLAVGIALTMYGRMEEADALVESLTRDKDPILRWAGMYTLAMAYCGSGNN 695
Query: 281 LKVQQLLHI 289
+++LLH+
Sbjct: 694 QAIRRLLHV 668
>24792
Length = 441
Score = 30.0 bits (66), Expect = 2.7, Method: Composition-based stats.
Identities = 12/24 (50%), Positives = 15/24 (62%)
Frame = +2
Query: 45 HEPGLLFCEWLCECSFWDKLLTDD 68
HE LFC CS+WDK+L +D
Sbjct: 113 HES*HLFCSLAICCSYWDKVLYND 184
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000322219 | hsapiens_gene_ensembl | X-linked
retinitis pigmentosa GTPase regulator.
[Source:Uniprot/SWISSPROT;Acc:Q92834]
(815 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
02938 302 4e-82
26574 55 8e-08
20162 53 4e-07
12101 49 1e-05
03352 42 0.001
01451 39 0.007
39525 35 0.094
>02938
Length = 1718
Score = 302 bits (773), Expect = 4e-82, Method: Compositional matrix adjust.
Identities = 168/385 (43%), Positives = 228/385 (59%), Gaps = 2/385 (0%)
Frame = +3
Query: 55 KLYMFGSNNWGQLGLGSKSAISKPTCVKALKPEKVKLAACGRNHTLVSTEGGNVYATGGN 114
+++MFG N++GQLG+G++ ++P+CVK+LK EK +L ACGR+HT+V+TE GN+YA G N
Sbjct: 18 RVFMFGPNDYGQLGIGAQKVANRPSCVKSLKHEKARLVACGRSHTIVATESGNIYAFGAN 197
Query: 115 NEGQLGL-GDTEERNTFHVISFFTSEHKIKQLSAGSNTSAALTEDGRLFMWGDNSEGQIG 173
EGQLG+ G TE V S + K+ L+AG + S ALTEDGR+F+WG N EGQ+G
Sbjct: 198 GEGQLGVEGVTETNLPKQVDSLQATPWKM--LAAGCDHSLALTEDGRVFVWGGNGEGQLG 371
Query: 174 LKNVSNVCVPQQVTIGKPVSWISCGYYHSAFVTTDGELYVFGEPENGKLGLPNQLLGNHR 233
+ S++ VP+Q+ +G+ V+ I+ GYYHSA VT GELY FGE + GKLGL N +
Sbjct: 372 MGEDSDIPVPRQLDVGQSVACIASGYYHSALVTESGELYTFGESDGGKLGL-NGDTDECK 548
Query: 234 TPQLVSEIPEKVIQVACGGEHTVVLTENA-VYXXXXXXXXXXXXXXXXXETSEPKVIENI 292
TPQ V I +KV V+CGG HTV LTE VY E+ P +++
Sbjct: 549 TPQQVMAINDKVKSVSCGGSHTVALTEKGEVYAFGEGSSGQLGLGVSTLESESPSLLK-- 722
Query: 293 RDQTISYISCGENHTALITDIGLMYTFGDGRHGKLGLGLENFTNHFIPTLCSNFLRFIVK 352
++ + CGEN T ++++ G +YTFGDGRHGKL LG E+F+N F+ T FL+F VK
Sbjct: 723 LPFKVAQVCCGENFTTVVSERGQLYTFGDGRHGKLALGQESFSNQFVCTKVDRFLKFNVK 902
Query: 353 LVACGGCHMVVFAAPHRGVAKEIEFDEINDTCLSVATFLPYSSLTSGNVLQRTLSAXXXX 412
ACGGCH++V A+P DE + T SLT RT SA
Sbjct: 903 KAACGGCHLIVMASPKLENGDVASEDEEEGQIMMNGTIRDSLSLT------RTFSARDRR 1064
Query: 413 XXXXXSPDSFSMRRTLPPIEGTLGL 437
P + RTLPP+ GL
Sbjct: 1065RNASPLP----LHRTLPPLGNNRGL 1127
Score = 66.6 bits (161), Expect = 4e-11, Method: Compositional matrix adjust.
Identities = 47/135 (34%), Positives = 66/135 (48%), Gaps = 11/135 (8%)
Frame = +3
Query: 7 LMPDSGAVFTFGKS---KFAENN-------PGKFWFKNDVPVHLSCGDEHSAVVTGNNKL 56
L+ +SG ++TFG+S K N P + ND +SCG H+ +T ++
Sbjct: 462 LVTESGELYTFGESDGGKLGLNGDTDECKTPQQVMAINDKVKSVSCGGSHTVALTEKGEV 641
Query: 57 YMFGSNNWGQLGLGSKSAISK-PTCVKALKPEKVKLAACGRNHTLVSTEGGNVYATGGNN 115
Y FG + GQLGLG + S+ P+ +K P KV CG N T V +E G +Y G
Sbjct: 642 YAFGEGSSGQLGLGVSTLESESPSLLKL--PFKVAQVCCGENFTTVVSERGQLYTFGDGR 815
Query: 116 EGQLGLGDTEERNTF 130
G+L LG N F
Sbjct: 816 HGKLALGQESFSNQF 860
Score = 47.0 bits (110), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 41/154 (26%), Positives = 71/154 (46%), Gaps = 15/154 (9%)
Frame = +3
Query: 8 MPDSGAVFTFGKSKFAENNPGKFWFKNDVP---------VHLSCGDEHSAVVTGNNKLYM 58
+ + G V+ FG+ + G +++ P + CG+ + VV+ +LY
Sbjct: 621 LTEKGEVYAFGEGSSGQLGLGVSTLESESPSLLKLPFKVAQVCCGENFTTVVSERGQLYT 800
Query: 59 FGSNNWGQLGLGSKSAISKPTCVKALKPEK--VKLAACGRNHTLVST----EGGNVYATG 112
FG G+L LG +S ++ C K + K VK AACG H +V E G+V A+
Sbjct: 801 FGDGRHGKLALGQESFSNQFVCTKVDRFLKFNVKKAACGGCHLIVMASPKLENGDV-ASE 977
Query: 113 GNNEGQLGLGDTEERNTFHVISFFTSEHKIKQLS 146
EGQ+ + T R++ + F++ + + S
Sbjct: 978 DEEEGQIMMNGT-IRDSLSLTRTFSARDRRRNAS 1076
>26574
Length = 441
Score = 55.5 bits (132), Expect = 8e-08, Method: Composition-based stats.
Identities = 32/96 (33%), Positives = 52/96 (54%)
Frame = +3
Query: 59 FGSNNWGQLGLGSKSAISKPTCVKALKPEKVKLAACGRNHTLVSTEGGNVYATGGNNEGQ 118
+G ++ +LG G+ + +P V AL+ +KV ACG H + T+ G V+ G N+EGQ
Sbjct: 6 WGKGDYHRLGHGTDDHVRRPRRVSALQGKKVIDVACGSLHCVACTDSGEVFTWGDNDEGQ 185
Query: 119 LGLGDTEERNTFHVISFFTSEHKIKQLSAGSNTSAA 154
LG G T +++ + KI +++ GS S A
Sbjct: 186 LGDGTTNAIQRPRMVAALQGK-KINRVACGSAHSLA 290
Score = 54.7 bits (130), Expect = 2e-07, Method: Composition-based stats.
Identities = 23/63 (36%), Positives = 39/63 (61%)
Frame = +3
Query: 38 VHLSCGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKSAISKPTCVKALKPEKVKLAACGRN 97
+ ++CG H T + +++ +G N+ GQLG G+ +AI +P V AL+ +K+ ACG
Sbjct: 99 IDVACGSLHCVACTDSGEVFTWGDNDEGQLGDGTTNAIQRPRMVAALQGKKINRVACGSA 278
Query: 98 HTL 100
H+L
Sbjct: 279 HSL 287
Score = 47.8 bits (112), Expect = 2e-05, Method: Composition-based stats.
Identities = 23/64 (35%), Positives = 36/64 (56%), Gaps = 2/64 (3%)
Frame = +3
Query: 141 KIKQLSAGSNTSAALTEDGRLFMWGDNSEGQIGLKNVSNVCVPQQVTI--GKPVSWISCG 198
K+ ++ GS A T+ G +F WGDN EGQ+G + + P+ V GK ++ ++CG
Sbjct: 93 KVIDVACGSLHCVACTDSGEVFTWGDNDEGQLGDGTTNAIQRPRMVAALQGKKINRVACG 272
Query: 199 YYHS 202
HS
Sbjct: 273 SAHS 284
Score = 41.6 bits (96), Expect = 0.001, Method: Composition-based stats.
Identities = 23/87 (26%), Positives = 43/87 (49%)
Frame = +3
Query: 286 PKVIENIRDQTISYISCGENHTALITDIGLMYTFGDGRHGKLGLGLENFTNHFIPTLCSN 345
P+ + ++ + + ++CG H TD G ++T+GD G+LG G N P + +
Sbjct: 63 PRRVSALQGKKVIDVACGSLHCVACTDSGEVFTWGDNDEGQLGDGTTNAIQR--PRMVAA 236
Query: 346 FLRFIVKLVACGGCHMVVFAAPHRGVA 372
+ VACG H + ++ H+ V+
Sbjct: 237 LQGKKINRVACGSAHSLAWST-HKPVS 314
Score = 34.3 bits (77), Expect = 0.18, Method: Composition-based stats.
Identities = 19/76 (25%), Positives = 34/76 (44%), Gaps = 1/76 (1%)
Frame = +3
Query: 233 RTPQLVSEIP-EKVIQVACGGEHTVVLTENAVYXXXXXXXXXXXXXXXXXETSEPKVIEN 291
R P+ VS + +KVI VACG H V T++ P+++
Sbjct: 57 RRPRRVSALQGKKVIDVACGSLHCVACTDSGEVFTWGDNDEGQLGDGTTNAIQRPRMVAA 236
Query: 292 IRDQTISYISCGENHT 307
++ + I+ ++CG H+
Sbjct: 237 LQGKKINRVACGSAHS 284
>20162
Length = 1121
Score = 53.1 bits (126), Expect = 4e-07, Method: Compositional matrix adjust.
Identities = 61/246 (24%), Positives = 95/246 (38%), Gaps = 30/246 (12%)
Frame = +1
Query: 45 EHSAVVTGNNKLYMFGSNNWGQLGLGSKSAI----SKPTCVKALKPEKVKL--------- 91
E S + N LY FG +GQLG S +K + P KV +
Sbjct: 109 EFSTMSDINGNLYSFGCPEYGQLGHNSDGKYFVTSNKMEYKCEMTPRKVSVFIEKTRDGH 288
Query: 92 -----------AACGRNHTLVSTEGGNVYATGGNNEGQLGLGDTEERNTFHVISFFTSEH 140
ACG NHTL+ +++ G G+LG + ++ +I FF
Sbjct: 289 VMPITDVDIREVACGLNHTLIMDSKKRLFSWGFGGYGRLGHAEPKDELVPRLIKFFDGPG 468
Query: 141 K-IKQLSAGSNTSAALTEDGRLFMWGDN---SEGQIGLKNVSNVCVPQQVTIGKPVSWIS 196
+ Q+ GS+ + E G L+ WG + E + K V ++ G V I
Sbjct: 469 RGGSQIQCGSSFCMTVNEHGALYFWGQSKPTGEATMYPKLVQDLS-------GWKVRSIG 627
Query: 197 CGYYHSAFVTTDGELYVFG-EPENGKLGLPNQLLGNHRTPQLVSEIPEKVIQ-VACGGEH 254
C Y S + D + +G P G+LG + + Q V + + VACG H
Sbjct: 628 C-CYRSIVLCADDSVVSWGPSPTYGELGYGENKMKSSTVAQEVKPLDGVYVHDVACGYAH 804
Query: 255 TVVLTE 260
T+++
Sbjct: 805 TLMIAR 822
Score = 31.2 bits (69), Expect = 1.6, Method: Compositional matrix adjust.
Identities = 13/37 (35%), Positives = 23/37 (62%)
Frame = +1
Query: 292 IRDQTISYISCGENHTALITDIGLMYTFGDGRHGKLG 328
I D I ++CG NHT ++ ++++G G +G+LG
Sbjct: 298 ITDVDIREVACGLNHTLIMDSKKRLFSWGFGGYGRLG 408
Score = 29.3 bits (64), Expect = 6.9, Method: Compositional matrix adjust.
Identities = 36/183 (19%), Positives = 67/183 (36%), Gaps = 12/183 (6%)
Frame = +1
Query: 195 ISCGYYHSAFVTTDGELYVFGEPENGKLGLPNQLLGNHRTPQLVSEIPEKVI-------- 246
++CG H+ + + L+ +G G+LG H P+ E+ ++I
Sbjct: 322 VACGLNHTLIMDSKKRLFSWGFGGYGRLG--------HAEPK--DELVPRLIKFFDGPGR 471
Query: 247 ---QVACGGEHTVVLTEN-AVYXXXXXXXXXXXXXXXXXETSEPKVIENIRDQTISYISC 302
Q+ CG + + E+ A+Y T PK+++++ + I C
Sbjct: 472 GGSQIQCGSSFCMTVNEHGALYFWGQSKPTGEA-------TMYPKLVQDLSGWKVRSIGC 630
Query: 303 GENHTALITDIGLMYTFGDGRHGKLGLGLENFTNHFIPTLCSNFLRFIVKLVACGGCHMV 362
L D ++ +G+LG G + + V VACG H +
Sbjct: 631 CYRSIVLCADDSVVSWGPSPTYGELGYGENKMKSSTVAQEVKPLDGVYVHDVACGYAHTL 810
Query: 363 VFA 365
+ A
Sbjct: 811 MIA 819
>12101
Length = 1020
Score = 48.5 bits (114), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 46/160 (28%), Positives = 69/160 (43%), Gaps = 9/160 (5%)
Frame = -2
Query: 56 LYMFGSNNWGQLGLGSKSAISKPTCVKALKPEK-----VKLAACGRNHTLVSTEGGNVYA 110
++ G NN+ QL ++ + L P K VK A G++HTL+ A
Sbjct: 860 IWAVGLNNYKQLAHPKETE-------RFLTPVKTEIKDVKQIAGGQHHTLILDNNMRCLA 702
Query: 111 TGGNNEGQLGLGDTEERNTFHVISFFTSEHKIKQLSAGSNTSAALTEDGRLFMWGDNSEG 170
G G+LGLG E T + K+ ++ G S +T DG+L+ WG S
Sbjct: 701 VGRPEYGRLGLGKVTEVVT-KPTAITQLNGKVNYVACGEACSFXITNDGKLYSWGMGSLL 525
Query: 171 QIGLKNVSNVCVPQQV----TIGKPVSWISCGYYHSAFVT 206
Q+G+ + + VP +V T K V G HS F+
Sbjct: 524 QLGVGDGDDEVVPVEVSSKNTQNKKVLLADGGGQHSVFLV 405
Score = 48.1 bits (113), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 46/161 (28%), Positives = 75/161 (46%), Gaps = 5/161 (3%)
Frame = -2
Query: 108 VYATGGNNEGQLGLGDTEERNTFHVISFFTSEHKIKQLSAGSNTSAALTEDGRLFMWGDN 167
++A G NN QL ER + T +KQ++ G + + L + R G
Sbjct: 860 IWAVGLNNYKQLAHPKETER---FLTPVKTEIKDVKQIAGGQHHTLILDNNMRCLAVGRP 690
Query: 168 SEGQIGLKNVSNVCV-PQQVT-IGKPVSWISCGYYHSAFVTTDGELYVFGEPENGKLGLP 225
G++GL V+ V P +T + V++++CG S +T DG+LY +G +LG+
Sbjct: 689 EYGRLGLGKVTEVVTKPTAITQLNGKVNYVACGEACSFXITNDGKLYSWGMGSLLQLGVG 510
Query: 226 NQLLGNHRTPQLVSEI---PEKVIQVACGGEHTVVLTENAV 263
+ + P VS +KV+ GG+H+V L E V
Sbjct: 509 DG--DDEVVPVEVSSKNTQNKKVLLADGGGQHSVFLVEADV 393
Score = 36.2 bits (82), Expect = 0.057, Method: Compositional matrix adjust.
Identities = 33/123 (26%), Positives = 54/123 (43%), Gaps = 3/123 (2%)
Frame = -2
Query: 245 VIQVACGGEHTVVLTENAVYXXXXXXXXXXXXXXXXXET-SEPKVIENIRDQTISYISCG 303
V Q+A G HT++L N E ++P I + + ++Y++CG
Sbjct: 767 VKQIAGGQHHTLILDNNMRCLAVGRPEYGRLGLGKVTEVVTKPTAITQLNGK-VNYVACG 591
Query: 304 ENHTALITDIGLMYTFGDGRHGKLGLGLENFTNHFIPTLCS--NFLRFIVKLVACGGCHM 361
E + IT+ G +Y++G G +LG+G + + +P S N V L GG H
Sbjct: 590 EACSFXITNDGKLYSWGMGSLLQLGVG--DGDDEVVPVEVSSKNTQNKKVLLADGGGQHS 417
Query: 362 VVF 364
V
Sbjct: 416 VFL 408
Score = 32.7 bits (73), Expect = 0.68, Method: Compositional matrix adjust.
Identities = 22/68 (32%), Positives = 35/68 (51%), Gaps = 2/68 (2%)
Frame = -2
Query: 39 HLSCGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKSAISKPTCV--KALKPEKVKLAACGR 96
+++CG+ S +T + KLY +G + QLG+G P V K + +KV LA G
Sbjct: 605 YVACGEACSFXITNDGKLYSWGMGSLLQLGVGDGDDEVVPVEVSSKNTQNKKVLLADGGG 426
Query: 97 NHTLVSTE 104
H++ E
Sbjct: 425 QHSVFLVE 402
>03352
Length = 935
Score = 41.6 bits (96), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 37/130 (28%), Positives = 55/130 (42%), Gaps = 16/130 (12%)
Frame = +2
Query: 7 LMPDSGAVFTFGKSKFAENN---------------PGKF-WFKNDVPVHLSCGDEHSAVV 50
++ D G+VF G +K E+ P K +N V ++C SAVV
Sbjct: 80 MLADDGSVFFVGLAKRGEDGDSGAAKGRRQPKSVKPKKMIRVENKQVVFVACNSGSSAVV 259
Query: 51 TGNNKLYMFGSNNWGQLGLGSKSAISKPTCVKALKPEKVKLAACGRNHTLVSTEGGNVYA 110
T + ++YMFG + + V LK V A G+ HT+ T G ++
Sbjct: 260 TKDGEVYMFGKD--------TSHCDHASGHVTDLKDVVVTQVALGKAHTVALTSKGQLFT 415
Query: 111 TGGNNEGQLG 120
G NN+GQ G
Sbjct: 416 FGINNKGQCG 445
Score = 41.2 bits (95), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 38/134 (28%), Positives = 60/134 (44%), Gaps = 10/134 (7%)
Frame = +2
Query: 136 FTSEHKIKQLSAGSNTSAAL--TEDGRLFMWGDNSEGQ-------IGLKNVSNVCVPQQV 186
T KI+Q++ G + AL +DG +F G G+ G + +V + +
Sbjct: 20 ITKSPKIQQVATGHEGAHALMLADDGSVFFVGLAKRGEDGDSGAAKGRRQPKSVKPKKMI 199
Query: 187 TI-GKPVSWISCGYYHSAFVTTDGELYVFGEPENGKLGLPNQLLGNHRTPQLVSEIPEKV 245
+ K V +++C SA VT DGE+Y+FG+ + +H + + V
Sbjct: 200 RVENKQVVFVACNSGSSAVVTKDGEVYMFGK---------DTSHCDHASGHVTDLKDVVV 352
Query: 246 IQVACGGEHTVVLT 259
QVA G HTV LT
Sbjct: 353 TQVALGKAHTVALT 394
Score = 36.2 bits (82), Expect = 0.056, Method: Compositional matrix adjust.
Identities = 32/137 (23%), Positives = 56/137 (40%), Gaps = 9/137 (6%)
Frame = +2
Query: 201 HSAFVTTDGELYVFGEPENGKLGLPNQLLGNHRTPQLVSEIPEKVIQV--------AC-G 251
H+ + DG ++ G + G+ G G R P+ V P+K+I+V AC
Sbjct: 71 HALMLADDGSVFFVGLAKRGEDGDSGAAKG-RRQPKSVK--PKKMIRVENKQVVFVACNS 241
Query: 252 GEHTVVLTENAVYXXXXXXXXXXXXXXXXXETSEPKVIENIRDQTISYISCGENHTALIT 311
G VV + VY + +++D ++ ++ G+ HT +T
Sbjct: 242 GSSAVVTKDGEVYMFGKDTSHCDHASGH---------VTDLKDVVVTQVALGKAHTVALT 394
Query: 312 DIGLMYTFGDGRHGKLG 328
G ++TFG G+ G
Sbjct: 395 SKGQLFTFGINNKGQCG 445
>01451
Length = 1229
Score = 39.3 bits (90), Expect = 0.007, Method: Compositional matrix adjust.
Identities = 18/49 (36%), Positives = 27/49 (55%)
Frame = -3
Query: 289 IENIRDQTISYISCGENHTALITDIGLMYTFGDGRHGKLGLGLENFTNH 337
IE + D + I+ G +H A +TD+G +YT G G+LG E F+
Sbjct: 1179 IEVLPDAVVVKIASGSDHIACLTDLGELYTLGCAEQGQLGRVAECFSTR 1033
>39525
Length = 450
Score = 35.4 bits (80), Expect = 0.094, Method: Composition-based stats.
Identities = 13/38 (34%), Positives = 27/38 (71%), Gaps = 2/38 (5%)
Frame = -3
Query: 141 KIKQLSAGSNTS--AALTEDGRLFMWGDNSEGQIGLKN 176
K++ +++G N A+T++G+++ WG N +GQ+GL +
Sbjct: 163 KVRTIASGCNACHCVAITDEGKVYTWGRNEKGQLGLSD 50
Score = 31.2 bits (69), Expect = 1.9, Method: Composition-based stats.
Identities = 17/41 (41%), Positives = 24/41 (58%)
Frame = -3
Query: 289 IENIRDQTISYISCGENHTALITDIGLMYTFGDGRHGKLGL 329
+E I+ +TI+ C H ITD G +YT+G G+LGL
Sbjct: 175 LEGIKVRTIAS-GCNACHCVAITDEGKVYTWGRNEKGQLGL 56
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000343671 | hsapiens_gene_ensembl | X-linked
retinitis pigmentosa GTPase regulator.
[Source:Uniprot/SWISSPROT;Acc:Q92834]
(1020 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
02938 302 6e-82
26574 56 9e-08
20162 53 7e-07
12101 49 1e-05
03352 42 0.001
01451 38 0.021
39525 35 0.18
01786 29 7.9
>02938
Length = 1718
Score = 302 bits (773), Expect = 6e-82, Method: Compositional matrix adjust.
Identities = 168/385 (43%), Positives = 228/385 (59%), Gaps = 2/385 (0%)
Frame = +3
Query: 55 KLYMFGSNNWGQLGLGSKSAISKPTCVKALKPEKVKLAACGRNHTLVSTEGGNVYATGGN 114
+++MFG N++GQLG+G++ ++P+CVK+LK EK +L ACGR+HT+V+TE GN+YA G N
Sbjct: 18 RVFMFGPNDYGQLGIGAQKVANRPSCVKSLKHEKARLVACGRSHTIVATESGNIYAFGAN 197
Query: 115 NEGQLGL-GDTEERNTFHVISFFTSEHKIKQLSAGSNTSAALTEDGRLFMWGDNSEGQIG 173
EGQLG+ G TE V S + K+ L+AG + S ALTEDGR+F+WG N EGQ+G
Sbjct: 198 GEGQLGVEGVTETNLPKQVDSLQATPWKM--LAAGCDHSLALTEDGRVFVWGGNGEGQLG 371
Query: 174 LKNVSNVCVPQQVTIGKPVSWISCGYYHSAFVTTDGELYVFGEPENGKLGLPNQLLGNHR 233
+ S++ VP+Q+ +G+ V+ I+ GYYHSA VT GELY FGE + GKLGL N +
Sbjct: 372 MGEDSDIPVPRQLDVGQSVACIASGYYHSALVTESGELYTFGESDGGKLGL-NGDTDECK 548
Query: 234 TPQLVSEIPEKVIQVACGGEHTVVLTENA-VYXXXXXXXXXXXXXXXXXETSEPKVIENI 292
TPQ V I +KV V+CGG HTV LTE VY E+ P +++
Sbjct: 549 TPQQVMAINDKVKSVSCGGSHTVALTEKGEVYAFGEGSSGQLGLGVSTLESESPSLLK-- 722
Query: 293 RDQTISYISCGENHTALITDIGLMYTFGDGRHGKLGLGLENFTNHFIPTLCSNFLRFIVK 352
++ + CGEN T ++++ G +YTFGDGRHGKL LG E+F+N F+ T FL+F VK
Sbjct: 723 LPFKVAQVCCGENFTTVVSERGQLYTFGDGRHGKLALGQESFSNQFVCTKVDRFLKFNVK 902
Query: 353 LVACGGCHMVVFAAPHRGVAKEIEFDEINDTCLSVATFLPYSSLTSGNVLQRTLSAXXXX 412
ACGGCH++V A+P DE + T SLT RT SA
Sbjct: 903 KAACGGCHLIVMASPKLENGDVASEDEEEGQIMMNGTIRDSLSLT------RTFSARDRR 1064
Query: 413 XXXXXSPDSFSMRRTLPPIEGTLGL 437
P + RTLPP+ GL
Sbjct: 1065RNASPLP----LHRTLPPLGNNRGL 1127
Score = 66.6 bits (161), Expect = 4e-11, Method: Compositional matrix adjust.
Identities = 47/135 (34%), Positives = 66/135 (48%), Gaps = 11/135 (8%)
Frame = +3
Query: 7 LMPDSGAVFTFGKS---KFAENN-------PGKFWFKNDVPVHLSCGDEHSAVVTGNNKL 56
L+ +SG ++TFG+S K N P + ND +SCG H+ +T ++
Sbjct: 462 LVTESGELYTFGESDGGKLGLNGDTDECKTPQQVMAINDKVKSVSCGGSHTVALTEKGEV 641
Query: 57 YMFGSNNWGQLGLGSKSAISK-PTCVKALKPEKVKLAACGRNHTLVSTEGGNVYATGGNN 115
Y FG + GQLGLG + S+ P+ +K P KV CG N T V +E G +Y G
Sbjct: 642 YAFGEGSSGQLGLGVSTLESESPSLLKL--PFKVAQVCCGENFTTVVSERGQLYTFGDGR 815
Query: 116 EGQLGLGDTEERNTF 130
G+L LG N F
Sbjct: 816 HGKLALGQESFSNQF 860
Score = 46.2 bits (108), Expect = 7e-05, Method: Compositional matrix adjust.
Identities = 41/154 (26%), Positives = 71/154 (46%), Gaps = 15/154 (9%)
Frame = +3
Query: 8 MPDSGAVFTFGKSKFAENNPGKFWFKNDVP---------VHLSCGDEHSAVVTGNNKLYM 58
+ + G V+ FG+ + G +++ P + CG+ + VV+ +LY
Sbjct: 621 LTEKGEVYAFGEGSSGQLGLGVSTLESESPSLLKLPFKVAQVCCGENFTTVVSERGQLYT 800
Query: 59 FGSNNWGQLGLGSKSAISKPTCVKALKPEK--VKLAACGRNHTLVST----EGGNVYATG 112
FG G+L LG +S ++ C K + K VK AACG H +V E G+V A+
Sbjct: 801 FGDGRHGKLALGQESFSNQFVCTKVDRFLKFNVKKAACGGCHLIVMASPKLENGDV-ASE 977
Query: 113 GNNEGQLGLGDTEERNTFHVISFFTSEHKIKQLS 146
EGQ+ + T R++ + F++ + + S
Sbjct: 978 DEEEGQIMMNGT-IRDSLSLTRTFSARDRRRNAS 1076
>26574
Length = 441
Score = 55.8 bits (133), Expect = 9e-08, Method: Composition-based stats.
Identities = 32/96 (33%), Positives = 52/96 (54%)
Frame = +3
Query: 59 FGSNNWGQLGLGSKSAISKPTCVKALKPEKVKLAACGRNHTLVSTEGGNVYATGGNNEGQ 118
+G ++ +LG G+ + +P V AL+ +KV ACG H + T+ G V+ G N+EGQ
Sbjct: 6 WGKGDYHRLGHGTDDHVRRPRRVSALQGKKVIDVACGSLHCVACTDSGEVFTWGDNDEGQ 185
Query: 119 LGLGDTEERNTFHVISFFTSEHKIKQLSAGSNTSAA 154
LG G T +++ + KI +++ GS S A
Sbjct: 186 LGDGTTNAIQRPRMVAALQGK-KINRVACGSAHSLA 290
Score = 54.7 bits (130), Expect = 2e-07, Method: Composition-based stats.
Identities = 23/63 (36%), Positives = 39/63 (61%)
Frame = +3
Query: 38 VHLSCGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKSAISKPTCVKALKPEKVKLAACGRN 97
+ ++CG H T + +++ +G N+ GQLG G+ +AI +P V AL+ +K+ ACG
Sbjct: 99 IDVACGSLHCVACTDSGEVFTWGDNDEGQLGDGTTNAIQRPRMVAALQGKKINRVACGSA 278
Query: 98 HTL 100
H+L
Sbjct: 279 HSL 287
Score = 48.1 bits (113), Expect = 2e-05, Method: Composition-based stats.
Identities = 23/64 (35%), Positives = 36/64 (56%), Gaps = 2/64 (3%)
Frame = +3
Query: 141 KIKQLSAGSNTSAALTEDGRLFMWGDNSEGQIGLKNVSNVCVPQQVTI--GKPVSWISCG 198
K+ ++ GS A T+ G +F WGDN EGQ+G + + P+ V GK ++ ++CG
Sbjct: 93 KVIDVACGSLHCVACTDSGEVFTWGDNDEGQLGDGTTNAIQRPRMVAALQGKKINRVACG 272
Query: 199 YYHS 202
HS
Sbjct: 273 SAHS 284
Score = 42.0 bits (97), Expect = 0.001, Method: Composition-based stats.
Identities = 23/87 (26%), Positives = 43/87 (49%)
Frame = +3
Query: 286 PKVIENIRDQTISYISCGENHTALITDIGLMYTFGDGRHGKLGLGLENFTNHFIPTLCSN 345
P+ + ++ + + ++CG H TD G ++T+GD G+LG G N P + +
Sbjct: 63 PRRVSALQGKKVIDVACGSLHCVACTDSGEVFTWGDNDEGQLGDGTTNAIQR--PRMVAA 236
Query: 346 FLRFIVKLVACGGCHMVVFAAPHRGVA 372
+ VACG H + ++ H+ V+
Sbjct: 237 LQGKKINRVACGSAHSLAWST-HKPVS 314
Score = 34.7 bits (78), Expect = 0.19, Method: Composition-based stats.
Identities = 19/76 (25%), Positives = 34/76 (44%), Gaps = 1/76 (1%)
Frame = +3
Query: 233 RTPQLVSEIP-EKVIQVACGGEHTVVLTENAVYXXXXXXXXXXXXXXXXXETSEPKVIEN 291
R P+ VS + +KVI VACG H V T++ P+++
Sbjct: 57 RRPRRVSALQGKKVIDVACGSLHCVACTDSGEVFTWGDNDEGQLGDGTTNAIQRPRMVAA 236
Query: 292 IRDQTISYISCGENHT 307
++ + I+ ++CG H+
Sbjct: 237 LQGKKINRVACGSAHS 284
>20162
Length = 1121
Score = 52.8 bits (125), Expect = 7e-07, Method: Compositional matrix adjust.
Identities = 62/246 (25%), Positives = 95/246 (38%), Gaps = 30/246 (12%)
Frame = +1
Query: 45 EHSAVVTGNNKLYMFGSNNWGQLGL---GSKSAISKPTCVKA-LKPEKVKL--------- 91
E S + N LY FG +GQLG G S K + P KV +
Sbjct: 109 EFSTMSDINGNLYSFGCPEYGQLGHNSDGKYFVTSNKMEYKCEMTPRKVSVFIEKTRDGH 288
Query: 92 -----------AACGRNHTLVSTEGGNVYATGGNNEGQLGLGDTEERNTFHVISFFTSEH 140
ACG NHTL+ +++ G G+LG + ++ +I FF
Sbjct: 289 VMPITDVDIREVACGLNHTLIMDSKKRLFSWGFGGYGRLGHAEPKDELVPRLIKFFDGPG 468
Query: 141 K-IKQLSAGSNTSAALTEDGRLFMWGDN---SEGQIGLKNVSNVCVPQQVTIGKPVSWIS 196
+ Q+ GS+ + E G L+ WG + E + K V ++ G V I
Sbjct: 469 RGGSQIQCGSSFCMTVNEHGALYFWGQSKPTGEATMYPKLVQDLS-------GWKVRSIG 627
Query: 197 CGYYHSAFVTTDGELYVFG-EPENGKLGLPNQLLGNHRTPQLVSEIPEKVIQ-VACGGEH 254
C Y S + D + +G P G+LG + + Q V + + VACG H
Sbjct: 628 C-CYRSIVLCADDSVVSWGPSPTYGELGYGENKMKSSTVAQEVKPLDGVYVHDVACGYAH 804
Query: 255 TVVLTE 260
T+++
Sbjct: 805 TLMIAR 822
Score = 31.2 bits (69), Expect = 2.2, Method: Compositional matrix adjust.
Identities = 13/37 (35%), Positives = 23/37 (62%)
Frame = +1
Query: 292 IRDQTISYISCGENHTALITDIGLMYTFGDGRHGKLG 328
I D I ++CG NHT ++ ++++G G +G+LG
Sbjct: 298 ITDVDIREVACGLNHTLIMDSKKRLFSWGFGGYGRLG 408
>12101
Length = 1020
Score = 48.9 bits (115), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 46/160 (28%), Positives = 69/160 (43%), Gaps = 9/160 (5%)
Frame = -2
Query: 56 LYMFGSNNWGQLGLGSKSAISKPTCVKALKPEK-----VKLAACGRNHTLVSTEGGNVYA 110
++ G NN+ QL ++ + L P K VK A G++HTL+ A
Sbjct: 860 IWAVGLNNYKQLAHPKETE-------RFLTPVKTEIKDVKQIAGGQHHTLILDNNMRCLA 702
Query: 111 TGGNNEGQLGLGDTEERNTFHVISFFTSEHKIKQLSAGSNTSAALTEDGRLFMWGDNSEG 170
G G+LGLG E T + K+ ++ G S +T DG+L+ WG S
Sbjct: 701 VGRPEYGRLGLGKVTEVVT-KPTAITQLNGKVNYVACGEACSFXITNDGKLYSWGMGSLL 525
Query: 171 QIGLKNVSNVCVPQQV----TIGKPVSWISCGYYHSAFVT 206
Q+G+ + + VP +V T K V G HS F+
Sbjct: 524 QLGVGDGDDEVVPVEVSSKNTQNKKVLLADGGGQHSVFLV 405
Score = 48.1 bits (113), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 46/161 (28%), Positives = 75/161 (46%), Gaps = 5/161 (3%)
Frame = -2
Query: 108 VYATGGNNEGQLGLGDTEERNTFHVISFFTSEHKIKQLSAGSNTSAALTEDGRLFMWGDN 167
++A G NN QL ER + T +KQ++ G + + L + R G
Sbjct: 860 IWAVGLNNYKQLAHPKETER---FLTPVKTEIKDVKQIAGGQHHTLILDNNMRCLAVGRP 690
Query: 168 SEGQIGLKNVSNVCV-PQQVT-IGKPVSWISCGYYHSAFVTTDGELYVFGEPENGKLGLP 225
G++GL V+ V P +T + V++++CG S +T DG+LY +G +LG+
Sbjct: 689 EYGRLGLGKVTEVVTKPTAITQLNGKVNYVACGEACSFXITNDGKLYSWGMGSLLQLGVG 510
Query: 226 NQLLGNHRTPQLVSEI---PEKVIQVACGGEHTVVLTENAV 263
+ + P VS +KV+ GG+H+V L E V
Sbjct: 509 DG--DDEVVPVEVSSKNTQNKKVLLADGGGQHSVFLVEADV 393
Score = 36.2 bits (82), Expect = 0.062, Method: Compositional matrix adjust.
Identities = 24/87 (27%), Positives = 42/87 (48%), Gaps = 1/87 (1%)
Frame = -2
Query: 245 VIQVACGGEHTVVLTENAVYXXXXXXXXXXXXXXXXXET-SEPKVIENIRDQTISYISCG 303
V Q+A G HT++L N E ++P I + + ++Y++CG
Sbjct: 767 VKQIAGGQHHTLILDNNMRCLAVGRPEYGRLGLGKVTEVVTKPTAITQLNGK-VNYVACG 591
Query: 304 ENHTALITDIGLMYTFGDGRHGKLGLG 330
E + IT+ G +Y++G G +LG+G
Sbjct: 590 EACSFXITNDGKLYSWGMGSLLQLGVG 510
Score = 32.3 bits (72), Expect = 0.96, Method: Compositional matrix adjust.
Identities = 22/68 (32%), Positives = 35/68 (51%), Gaps = 2/68 (2%)
Frame = -2
Query: 39 HLSCGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKSAISKPTCV--KALKPEKVKLAACGR 96
+++CG+ S +T + KLY +G + QLG+G P V K + +KV LA G
Sbjct: 605 YVACGEACSFXITNDGKLYSWGMGSLLQLGVGDGDDEVVPVEVSSKNTQNKKVLLADGGG 426
Query: 97 NHTLVSTE 104
H++ E
Sbjct: 425 QHSVFLVE 402
>03352
Length = 935
Score = 41.6 bits (96), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 37/130 (28%), Positives = 55/130 (42%), Gaps = 16/130 (12%)
Frame = +2
Query: 7 LMPDSGAVFTFGKSKFAENN---------------PGKFW-FKNDVPVHLSCGDEHSAVV 50
++ D G+VF G +K E+ P K +N V ++C SAVV
Sbjct: 80 MLADDGSVFFVGLAKRGEDGDSGAAKGRRQPKSVKPKKMIRVENKQVVFVACNSGSSAVV 259
Query: 51 TGNNKLYMFGSNNWGQLGLGSKSAISKPTCVKALKPEKVKLAACGRNHTLVSTEGGNVYA 110
T + ++YMFG + + V LK V A G+ HT+ T G ++
Sbjct: 260 TKDGEVYMFGKD--------TSHCDHASGHVTDLKDVVVTQVALGKAHTVALTSKGQLFT 415
Query: 111 TGGNNEGQLG 120
G NN+GQ G
Sbjct: 416 FGINNKGQCG 445
Score = 41.2 bits (95), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 38/134 (28%), Positives = 60/134 (44%), Gaps = 10/134 (7%)
Frame = +2
Query: 136 FTSEHKIKQLSAGSNTSAAL--TEDGRLFMWGDNSEGQ-------IGLKNVSNVCVPQQV 186
T KI+Q++ G + AL +DG +F G G+ G + +V + +
Sbjct: 20 ITKSPKIQQVATGHEGAHALMLADDGSVFFVGLAKRGEDGDSGAAKGRRQPKSVKPKKMI 199
Query: 187 TI-GKPVSWISCGYYHSAFVTTDGELYVFGEPENGKLGLPNQLLGNHRTPQLVSEIPEKV 245
+ K V +++C SA VT DGE+Y+FG+ + +H + + V
Sbjct: 200 RVENKQVVFVACNSGSSAVVTKDGEVYMFGK---------DTSHCDHASGHVTDLKDVVV 352
Query: 246 IQVACGGEHTVVLT 259
QVA G HTV LT
Sbjct: 353 TQVALGKAHTVALT 394
Score = 35.8 bits (81), Expect = 0.081, Method: Compositional matrix adjust.
Identities = 32/137 (23%), Positives = 56/137 (40%), Gaps = 9/137 (6%)
Frame = +2
Query: 201 HSAFVTTDGELYVFGEPENGKLGLPNQLLGNHRTPQLVSEIPEKVIQV--------AC-G 251
H+ + DG ++ G + G+ G G R P+ V P+K+I+V AC
Sbjct: 71 HALMLADDGSVFFVGLAKRGEDGDSGAAKGR-RQPKSVK--PKKMIRVENKQVVFVACNS 241
Query: 252 GEHTVVLTENAVYXXXXXXXXXXXXXXXXXETSEPKVIENIRDQTISYISCGENHTALIT 311
G VV + VY + +++D ++ ++ G+ HT +T
Sbjct: 242 GSSAVVTKDGEVYMFGKDTSHCDHASGH---------VTDLKDVVVTQVALGKAHTVALT 394
Query: 312 DIGLMYTFGDGRHGKLG 328
G ++TFG G+ G
Sbjct: 395 SKGQLFTFGINNKGQCG 445
>01451
Length = 1229
Score = 38.1 bits (87), Expect = 0.021, Method: Composition-based stats.
Identities = 19/51 (37%), Positives = 28/51 (54%)
Frame = -3
Query: 285 EPKVIENIRDQTISYISCGENHTALITDIGLMYTFGDGRHGKLGLGLENFT 335
E IE + D + I+ G +H A +TD+G +YT G G+LG E F+
Sbjct: 1191 EKTPIEVLPDAVVVKIASGSDHIACLTDLGELYTLGCAEQGQLGRVAECFS 1039
>39525
Length = 450
Score = 34.7 bits (78), Expect = 0.18, Method: Composition-based stats.
Identities = 13/38 (34%), Positives = 27/38 (71%), Gaps = 2/38 (5%)
Frame = -3
Query: 141 KIKQLSAGSNTS--AALTEDGRLFMWGDNSEGQIGLKN 176
K++ +++G N A+T++G+++ WG N +GQ+GL +
Sbjct: 163 KVRTIASGCNACHCVAITDEGKVYTWGRNEKGQLGLSD 50
Score = 30.4 bits (67), Expect = 3.5, Method: Composition-based stats.
Identities = 17/41 (41%), Positives = 24/41 (58%)
Frame = -3
Query: 289 IENIRDQTISYISCGENHTALITDIGLMYTFGDGRHGKLGL 329
+E I+ +TI+ C H ITD G +YT+G G+LGL
Sbjct: 175 LEGIKVRTIAS-GCNACHCVAITDEGKVYTWGRNEKGQLGL 56
>01786
Length = 1290
Score = 29.3 bits (64), Expect = 7.9, Method: Composition-based stats.
Identities = 14/36 (38%), Positives = 20/36 (55%)
Frame = +3
Query: 217 PENGKLGLPNQLLGNHRTPQLVSEIPEKVIQVACGG 252
P N KL +P +L G+ RT + +S K + V C G
Sbjct: 945 PSNSKLCIPQELSGHTRTVRSLSNCLVKCVLVDCNG 1052
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000339531 | hsapiens_gene_ensembl | X-linked
retinitis pigmentosa GTPase regulator.
[Source:Uniprot/SWISSPROT;Acc:Q92834]
(646 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
02938 301 7e-82
26574 55 8e-08
20162 54 2e-07
12101 48 1e-05
03352 42 8e-04
01451 39 0.005
39525 36 0.050
>02938
Length = 1718
Score = 301 bits (770), Expect = 7e-82, Method: Compositional matrix adjust.
Identities = 165/384 (42%), Positives = 225/384 (58%), Gaps = 1/384 (0%)
Frame = +3
Query: 55 KLYMFGSNNWGQLGLGSKSAISKPTCVKALKPEKVKLAACGRNHTLVSTEGGNVYATGGN 114
+++MFG N++GQLG+G++ ++P+CVK+LK EK +L ACGR+HT+V+TE GN+YA G N
Sbjct: 18 RVFMFGPNDYGQLGIGAQKVANRPSCVKSLKHEKARLVACGRSHTIVATESGNIYAFGAN 197
Query: 115 NEGQLGLGDTEERNTFHVISFFTSEHKIKQLSAGSNTSAALTEDGRLFMWGDNSEGQIGL 174
EGQLG+ E N + + K L+AG + S ALTEDGR+F+WG N EGQ+G+
Sbjct: 198 GEGQLGVEGVTETNLPKQVDSLQAT-PWKMLAAGCDHSLALTEDGRVFVWGGNGEGQLGM 374
Query: 175 KNVSNVCVPQQVTIGKPVSWISCGYYHSAFVTTDGELYVFGEPENGKLGLPNQLLGNHRT 234
S++ VP+Q+ +G+ V+ I+ GYYHSA VT GELY FGE + GKLGL N +T
Sbjct: 375 GEDSDIPVPRQLDVGQSVACIASGYYHSALVTESGELYTFGESDGGKLGL-NGDTDECKT 551
Query: 235 PQLVSEIPEKVIQVACGGEHTVVLTENA-VYXXXXXXXXXXXXXXXXXETSEPKVIENIR 293
PQ V I +KV V+CGG HTV LTE VY E+ P +++
Sbjct: 552 PQQVMAINDKVKSVSCGGSHTVALTEKGEVYAFGEGSSGQLGLGVSTLESESPSLLK--L 725
Query: 294 DQTISYISCGENHTALITDIGLMYTFGDGRHGKLGLGLENFTNHFIPTLCSNFLRFIVKL 353
++ + CGEN T ++++ G +YTFGDGRHGKL LG E+F+N F+ T FL+F VK
Sbjct: 726 PFKVAQVCCGENFTTVVSERGQLYTFGDGRHGKLALGQESFSNQFVCTKVDRFLKFNVKK 905
Query: 354 VACGGCHMVVFAAPHRGVAKEIEFDEINDTCLSVATFLPYSSLTSGNVLQRTLSAXXXXX 413
ACGGCH++V A+P DE + T SLT RT SA
Sbjct: 906 AACGGCHLIVMASPKLENGDVASEDEEEGQIMMNGTIRDSLSLT------RTFSARDRRR 1067
Query: 414 XXXXSPDSFSMRRTLPPIEGTLGL 437
P + RTLPP+ GL
Sbjct: 1068NASPLP----LHRTLPPLGNNRGL 1127
Score = 65.5 bits (158), Expect = 6e-11, Method: Compositional matrix adjust.
Identities = 47/135 (34%), Positives = 66/135 (48%), Gaps = 11/135 (8%)
Frame = +3
Query: 7 LMPDSGAVFTFGKS---KFAEN-------NPGKFWFKNDVPVHLSCGDEHSAVVTGNNKL 56
L+ +SG ++TFG+S K N P + ND +SCG H+ +T ++
Sbjct: 462 LVTESGELYTFGESDGGKLGLNGDTDECKTPQQVMAINDKVKSVSCGGSHTVALTEKGEV 641
Query: 57 YMFGSNNWGQLGLGSKSAISK-PTCVKALKPEKVKLAACGRNHTLVSTEGGNVYATGGNN 115
Y FG + GQLGLG + S+ P+ +K P KV CG N T V +E G +Y G
Sbjct: 642 YAFGEGSSGQLGLGVSTLESESPSLLKL--PFKVAQVCCGENFTTVVSERGQLYTFGDGR 815
Query: 116 EGQLGLGDTEERNTF 130
G+L LG N F
Sbjct: 816 HGKLALGQESFSNQF 860
Score = 47.0 bits (110), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 41/154 (26%), Positives = 71/154 (46%), Gaps = 15/154 (9%)
Frame = +3
Query: 8 MPDSGAVFTFGKSKFAENNPGKFWFKNDVP---------VHLSCGDEHSAVVTGNNKLYM 58
+ + G V+ FG+ + G +++ P + CG+ + VV+ +LY
Sbjct: 621 LTEKGEVYAFGEGSSGQLGLGVSTLESESPSLLKLPFKVAQVCCGENFTTVVSERGQLYT 800
Query: 59 FGSNNWGQLGLGSKSAISKPTCVKALKPEK--VKLAACGRNHTLV----STEGGNVYATG 112
FG G+L LG +S ++ C K + K VK AACG H +V E G+V A+
Sbjct: 801 FGDGRHGKLALGQESFSNQFVCTKVDRFLKFNVKKAACGGCHLIVMASPKLENGDV-ASE 977
Query: 113 GNNEGQLGLGDTEERNTFHVISFFTSEHKIKQLS 146
EGQ+ + T R++ + F++ + + S
Sbjct: 978 DEEEGQIMMNGT-IRDSLSLTRTFSARDRRRNAS 1076
>26574
Length = 441
Score = 55.1 bits (131), Expect = 8e-08, Method: Composition-based stats.
Identities = 32/96 (33%), Positives = 52/96 (54%)
Frame = +3
Query: 59 FGSNNWGQLGLGSKSAISKPTCVKALKPEKVKLAACGRNHTLVSTEGGNVYATGGNNEGQ 118
+G ++ +LG G+ + +P V AL+ +KV ACG H + T+ G V+ G N+EGQ
Sbjct: 6 WGKGDYHRLGHGTDDHVRRPRRVSALQGKKVIDVACGSLHCVACTDSGEVFTWGDNDEGQ 185
Query: 119 LGLGDTEERNTFHVISFFTSEHKIKQLSAGSNTSAA 154
LG G T +++ + KI +++ GS S A
Sbjct: 186 LGDGTTNAIQRPRMVAALQGK-KINRVACGSAHSLA 290
Score = 54.3 bits (129), Expect = 2e-07, Method: Composition-based stats.
Identities = 23/63 (36%), Positives = 39/63 (61%)
Frame = +3
Query: 38 VHLSCGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKSAISKPTCVKALKPEKVKLAACGRN 97
+ ++CG H T + +++ +G N+ GQLG G+ +AI +P V AL+ +K+ ACG
Sbjct: 99 IDVACGSLHCVACTDSGEVFTWGDNDEGQLGDGTTNAIQRPRMVAALQGKKINRVACGSA 278
Query: 98 HTL 100
H+L
Sbjct: 279 HSL 287
Score = 47.8 bits (112), Expect = 2e-05, Method: Composition-based stats.
Identities = 23/64 (35%), Positives = 36/64 (56%), Gaps = 2/64 (3%)
Frame = +3
Query: 141 KIKQLSAGSNTSAALTEDGRLFMWGDNSEGQIGLKNVSNVCVPQQVTI--GKPVSWISCG 198
K+ ++ GS A T+ G +F WGDN EGQ+G + + P+ V GK ++ ++CG
Sbjct: 93 KVIDVACGSLHCVACTDSGEVFTWGDNDEGQLGDGTTNAIQRPRMVAALQGKKINRVACG 272
Query: 199 YYHS 202
HS
Sbjct: 273 SAHS 284
Score = 41.6 bits (96), Expect = 0.001, Method: Composition-based stats.
Identities = 23/87 (26%), Positives = 43/87 (49%)
Frame = +3
Query: 286 PKVIENIRDQTISYISCGENHTALITDIGLMYTFGDGRHGKLGLGLENFTNHFIPTLCSN 345
P+ + ++ + + ++CG H TD G ++T+GD G+LG G N P + +
Sbjct: 63 PRRVSALQGKKVIDVACGSLHCVACTDSGEVFTWGDNDEGQLGDGTTNAIQR--PRMVAA 236
Query: 346 FLRFIVKLVACGGCHMVVFAAPHRGVA 372
+ VACG H + ++ H+ V+
Sbjct: 237 LQGKKINRVACGSAHSLAWST-HKPVS 314
Score = 33.9 bits (76), Expect = 0.21, Method: Composition-based stats.
Identities = 19/76 (25%), Positives = 34/76 (44%), Gaps = 1/76 (1%)
Frame = +3
Query: 233 RTPQLVSEIP-EKVIQVACGGEHTVVLTENAVYXXXXXXXXXXXXXXXXXETSEPKVIEN 291
R P+ VS + +KVI VACG H V T++ P+++
Sbjct: 57 RRPRRVSALQGKKVIDVACGSLHCVACTDSGEVFTWGDNDEGQLGDGTTNAIQRPRMVAA 236
Query: 292 IRDQTISYISCGENHT 307
++ + I+ ++CG H+
Sbjct: 237 LQGKKINRVACGSAHS 284
>20162
Length = 1121
Score = 53.9 bits (128), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 61/246 (24%), Positives = 95/246 (38%), Gaps = 30/246 (12%)
Frame = +1
Query: 45 EHSAVVTGNNKLYMFGSNNWGQLGLGSKSAI----SKPTCVKALKPEKVKL--------- 91
E S + N LY FG +GQLG S +K + P KV +
Sbjct: 109 EFSTMSDINGNLYSFGCPEYGQLGHNSDGKYFVTSNKMEYKCEMTPRKVSVFIEKTRDGH 288
Query: 92 -----------AACGRNHTLVSTEGGNVYATGGNNEGQLGLGDTEERNTFHVISFFTSEH 140
ACG NHTL+ +++ G G+LG + ++ +I FF
Sbjct: 289 VMPITDVDIREVACGLNHTLIMDSKKRLFSWGFGGYGRLGHAEPKDELVPRLIKFFDGPG 468
Query: 141 K-IKQLSAGSNTSAALTEDGRLFMWGDNS---EGQIGLKNVSNVCVPQQVTIGKPVSWIS 196
+ Q+ GS+ + E G L+ WG + E + K V ++ G V I
Sbjct: 469 RGGSQIQCGSSFCMTVNEHGALYFWGQSKPTGEATMYPKLVQDLS-------GWKVRSIG 627
Query: 197 CGYYHSAFVTTDGELYVFG-EPENGKLGLPNQLLGNHRTPQLVSEIPEKVIQ-VACGGEH 254
C Y S + D + +G P G+LG + + Q V + + VACG H
Sbjct: 628 C-CYRSIVLCADDSVVSWGPSPTYGELGYGENKMKSSTVAQEVKPLDGVYVHDVACGYAH 804
Query: 255 TVVLTE 260
T+++
Sbjct: 805 TLMIAR 822
Score = 31.2 bits (69), Expect = 1.3, Method: Compositional matrix adjust.
Identities = 13/37 (35%), Positives = 23/37 (62%)
Frame = +1
Query: 292 IRDQTISYISCGENHTALITDIGLMYTFGDGRHGKLG 328
I D I ++CG NHT ++ ++++G G +G+LG
Sbjct: 298 ITDVDIREVACGLNHTLIMDSKKRLFSWGFGGYGRLG 408
Score = 30.0 bits (66), Expect = 2.9, Method: Compositional matrix adjust.
Identities = 36/183 (19%), Positives = 67/183 (36%), Gaps = 12/183 (6%)
Frame = +1
Query: 195 ISCGYYHSAFVTTDGELYVFGEPENGKLGLPNQLLGNHRTPQLVSEIPEKVI-------- 246
++CG H+ + + L+ +G G+LG H P+ E+ ++I
Sbjct: 322 VACGLNHTLIMDSKKRLFSWGFGGYGRLG--------HAEPK--DELVPRLIKFFDGPGR 471
Query: 247 ---QVACGGEHTVVLTEN-AVYXXXXXXXXXXXXXXXXXETSEPKVIENIRDQTISYISC 302
Q+ CG + + E+ A+Y T PK+++++ + I C
Sbjct: 472 GGSQIQCGSSFCMTVNEHGALYFWGQSKPTGEA-------TMYPKLVQDLSGWKVRSIGC 630
Query: 303 GENHTALITDIGLMYTFGDGRHGKLGLGLENFTNHFIPTLCSNFLRFIVKLVACGGCHMV 362
L D ++ +G+LG G + + V VACG H +
Sbjct: 631 CYRSIVLCADDSVVSWGPSPTYGELGYGENKMKSSTVAQEVKPLDGVYVHDVACGYAHTL 810
Query: 363 VFA 365
+ A
Sbjct: 811 MIA 819
>12101
Length = 1020
Score = 48.1 bits (113), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 46/159 (28%), Positives = 69/159 (43%), Gaps = 9/159 (5%)
Frame = -2
Query: 56 LYMFGSNNWGQLGLGSKSAISKPTCVKALKPEK-----VKLAACGRNHTLVSTEGGNVYA 110
++ G NN+ QL ++ + L P K VK A G++HTL+ A
Sbjct: 860 IWAVGLNNYKQLAHPKETE-------RFLTPVKTEIKDVKQIAGGQHHTLILDNNMRCLA 702
Query: 111 TGGNNEGQLGLGDTEERNTFHVISFFTSEHKIKQLSAGSNTSAALTEDGRLFMWGDNSEG 170
G G+LGLG E T + K+ ++ G S +T DG+L+ WG S
Sbjct: 701 VGRPEYGRLGLGKVTEVVT-KPTAITQLNGKVNYVACGEACSFXITNDGKLYSWGMGSLL 525
Query: 171 QIGLKNVSNVCVPQQV----TIGKPVSWISCGYYHSAFV 205
Q+G+ + + VP +V T K V G HS F+
Sbjct: 524 QLGVGDGDDEVVPVEVSSKNTQNKKVLLADGGGQHSVFL 408
Score = 47.8 bits (112), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 46/161 (28%), Positives = 75/161 (46%), Gaps = 5/161 (3%)
Frame = -2
Query: 108 VYATGGNNEGQLGLGDTEERNTFHVISFFTSEHKIKQLSAGSNTSAALTEDGRLFMWGDN 167
++A G NN QL ER + T +KQ++ G + + L + R G
Sbjct: 860 IWAVGLNNYKQLAHPKETER---FLTPVKTEIKDVKQIAGGQHHTLILDNNMRCLAVGRP 690
Query: 168 SEGQIGLKNVSNVCV-PQQVT-IGKPVSWISCGYYHSAFVTTDGELYVFGEPENGKLGLP 225
G++GL V+ V P +T + V++++CG S +T DG+LY +G +LG+
Sbjct: 689 EYGRLGLGKVTEVVTKPTAITQLNGKVNYVACGEACSFXITNDGKLYSWGMGSLLQLGVG 510
Query: 226 NQLLGNHRTPQLVSEI---PEKVIQVACGGEHTVVLTENAV 263
+ + P VS +KV+ GG+H+V L E V
Sbjct: 509 DG--DDEVVPVEVSSKNTQNKKVLLADGGGQHSVFLVEADV 393
Score = 36.2 bits (82), Expect = 0.048, Method: Compositional matrix adjust.
Identities = 33/123 (26%), Positives = 54/123 (43%), Gaps = 3/123 (2%)
Frame = -2
Query: 245 VIQVACGGEHTVVLTENAVYXXXXXXXXXXXXXXXXXET-SEPKVIENIRDQTISYISCG 303
V Q+A G HT++L N E ++P I + + ++Y++CG
Sbjct: 767 VKQIAGGQHHTLILDNNMRCLAVGRPEYGRLGLGKVTEVVTKPTAITQLNGK-VNYVACG 591
Query: 304 ENHTALITDIGLMYTFGDGRHGKLGLGLENFTNHFIPTLCS--NFLRFIVKLVACGGCHM 361
E + IT+ G +Y++G G +LG+G + + +P S N V L GG H
Sbjct: 590 EACSFXITNDGKLYSWGMGSLLQLGVG--DGDDEVVPVEVSSKNTQNKKVLLADGGGQHS 417
Query: 362 VVF 364
V
Sbjct: 416 VFL 408
Score = 32.0 bits (71), Expect = 0.72, Method: Compositional matrix adjust.
Identities = 22/68 (32%), Positives = 35/68 (51%), Gaps = 2/68 (2%)
Frame = -2
Query: 39 HLSCGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKSAISKPTCV--KALKPEKVKLAACGR 96
+++CG+ S +T + KLY +G + QLG+G P V K + +KV LA G
Sbjct: 605 YVACGEACSFXITNDGKLYSWGMGSLLQLGVGDGDDEVVPVEVSSKNTQNKKVLLADGGG 426
Query: 97 NHTLVSTE 104
H++ E
Sbjct: 425 QHSVFLVE 402
>03352
Length = 935
Score = 42.0 bits (97), Expect = 8e-04, Method: Compositional matrix adjust.
Identities = 38/134 (28%), Positives = 60/134 (44%), Gaps = 10/134 (7%)
Frame = +2
Query: 136 FTSEHKIKQLSAGSNTSAAL--TEDGRLFMWGDNSEGQ-------IGLKNVSNVCVPQQV 186
T KI+Q++ G + AL +DG +F G G+ G + +V + +
Sbjct: 20 ITKSPKIQQVATGHEGAHALMLADDGSVFFVGLAKRGEDGDSGAAKGRRQPKSVKPKKMI 199
Query: 187 TI-GKPVSWISCGYYHSAFVTTDGELYVFGEPENGKLGLPNQLLGNHRTPQLVSEIPEKV 245
+ K V +++C SA VT DGE+Y+FG+ + +H + + V
Sbjct: 200 RVENKQVVFVACNSGSSAVVTKDGEVYMFGK---------DTSHCDHASGHVTDLKDVVV 352
Query: 246 IQVACGGEHTVVLT 259
QVA G HTV LT
Sbjct: 353 TQVALGKAHTVALT 394
Score = 41.6 bits (96), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 37/130 (28%), Positives = 55/130 (42%), Gaps = 16/130 (12%)
Frame = +2
Query: 7 LMPDSGAVFTFGKSKFAEN---------------NPGKF-WFKNDVPVHLSCGDEHSAVV 50
++ D G+VF G +K E+ P K +N V ++C SAVV
Sbjct: 80 MLADDGSVFFVGLAKRGEDGDSGAAKGRRQPKSVKPKKMIRVENKQVVFVACNSGSSAVV 259
Query: 51 TGNNKLYMFGSNNWGQLGLGSKSAISKPTCVKALKPEKVKLAACGRNHTLVSTEGGNVYA 110
T + ++YMFG + + V LK V A G+ HT+ T G ++
Sbjct: 260 TKDGEVYMFGKD--------TSHCDHASGHVTDLKDVVVTQVALGKAHTVALTSKGQLFT 415
Query: 111 TGGNNEGQLG 120
G NN+GQ G
Sbjct: 416 FGINNKGQCG 445
Score = 36.2 bits (82), Expect = 0.045, Method: Compositional matrix adjust.
Identities = 32/137 (23%), Positives = 56/137 (40%), Gaps = 9/137 (6%)
Frame = +2
Query: 201 HSAFVTTDGELYVFGEPENGKLGLPNQLLGNHRTPQLVSEIPEKVIQV--------AC-G 251
H+ + DG ++ G + G+ G G R P+ V P+K+I+V AC
Sbjct: 71 HALMLADDGSVFFVGLAKRGEDGDSGAAKG-RRQPKSVK--PKKMIRVENKQVVFVACNS 241
Query: 252 GEHTVVLTENAVYXXXXXXXXXXXXXXXXXETSEPKVIENIRDQTISYISCGENHTALIT 311
G VV + VY + +++D ++ ++ G+ HT +T
Sbjct: 242 GSSAVVTKDGEVYMFGKDTSHCDHASGH---------VTDLKDVVVTQVALGKAHTVALT 394
Query: 312 DIGLMYTFGDGRHGKLG 328
G ++TFG G+ G
Sbjct: 395 SKGQLFTFGINNKGQCG 445
>01451
Length = 1229
Score = 39.3 bits (90), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 18/49 (36%), Positives = 27/49 (55%)
Frame = -3
Query: 289 IENIRDQTISYISCGENHTALITDIGLMYTFGDGRHGKLGLGLENFTNH 337
IE + D + I+ G +H A +TD+G +YT G G+LG E F+
Sbjct: 1179 IEVLPDAVVVKIASGSDHIACLTDLGELYTLGCAEQGQLGRVAECFSTR 1033
>39525
Length = 450
Score = 35.8 bits (81), Expect = 0.050, Method: Composition-based stats.
Identities = 13/38 (34%), Positives = 27/38 (71%), Gaps = 2/38 (5%)
Frame = -3
Query: 141 KIKQLSAGSNTS--AALTEDGRLFMWGDNSEGQIGLKN 176
K++ +++G N A+T++G+++ WG N +GQ+GL +
Sbjct: 163 KVRTIASGCNACHCVAITDEGKVYTWGRNEKGQLGLSD 50
Score = 31.6 bits (70), Expect = 1.1, Method: Composition-based stats.
Identities = 17/41 (41%), Positives = 24/41 (58%)
Frame = -3
Query: 289 IENIRDQTISYISCGENHTALITDIGLMYTFGDGRHGKLGL 329
+E I+ +TI+ C H ITD G +YT+G G+LGL
Sbjct: 175 LEGIKVRTIAS-GCNACHCVAITDEGKVYTWGRNEKGQLGL 56
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000347890 | hsapiens_gene_ensembl | Dynamin-2 (EC
3.6.5.5). [Source:Uniprot/SWISSPROT;Acc:P50570]
(870 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
29522 301 7e-82
38072 96 4e-38
13952 35 0.15
14762 32 1.0
15376 32 1.1
>29522
Length = 698
Score = 301 bits (771), Expect = 7e-82, Method: Compositional matrix adjust.
Identities = 141/210 (67%), Positives = 173/210 (82%)
Frame = -3
Query: 344 IEGSGDQVDTLELSGGARINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLF 403
IEG G QV T +LSGGA+INRIFHERFPFELVKMEFDE++LR+EI I+NIHG+RTGLF
Sbjct: 696 IEGFGAQVSTEDLSGGAKINRIFHERFPFELVKMEFDERELRKEIGITIRNIHGIRTGLF 517
Query: 404 TPDLAFEAIVKKQVVKLKEPCLKCVDLVIQELINTVRQCTSKLSSYPRLREETERIVTTY 463
TPD+AFE+IV KQ+ +LKEP L CVDLVI EL VR+ K+S YPRLREETERIV +
Sbjct: 516 TPDMAFESIVVKQIERLKEPSLHCVDLVITELSQVVRKAGEKMSRYPRLREETERIVNSR 337
Query: 464 IREREGRTKDQILLLIDIEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQPETLVIRR 523
IRE+E R K+QIL LID + +Y+NTNHEDFIGF+NAQQ++ + KR + NQ VIR+
Sbjct: 336 IREQEQRAKEQILTLIDFQLAYMNTNHEDFIGFSNAQQKAESQSSKRKMGNQ----VIRK 169
Query: 524 GWLTINNISLMKGGSKEYWFVLTAESLSWY 553
GWL+++NIS +KGGSK++WFVLTAESLSW+
Sbjct: 168 GWLSLHNISFIKGGSKDFWFVLTAESLSWF 79
>38072
Length = 513
Score = 96.3 bits (238), Expect(2) = 4e-38, Method: Compositional matrix adjust.
Identities = 48/78 (61%), Positives = 60/78 (76%)
Frame = -3
Query: 611 EDVDSWKASFLRAGVYPEKDQAENEDGAQENTFSMDPQLERQVETIRNLVDSYVAIINKS 670
EDVDSWKASFLRAGVYPE+ E+ + + PQLERQVETIRNLVDSY+ I+NK+
Sbjct: 511 EDVDSWKASFLRAGVYPERSSDESSSSKDDYSSMD-PQLERQVETIRNLVDSYMKIVNKT 335
Query: 671 IRDLMPKTIMHLMINNTK 688
RDL+PKTIMH+++ +
Sbjct: 334 QRDLIPKTIMHIIVKKCE 281
Score = 81.3 bits (199), Expect(2) = 4e-38, Method: Compositional matrix adjust.
Identities = 42/86 (48%), Positives = 56/86 (65%)
Frame = -1
Query: 686 NTKAFIHHELLAYLYSSADQSSLMEESADQAQRRDDMLRMYHALKEALNIIGDIXXXXXX 745
N K+FI +LLA+LYS+ DQS++MEES ++AQRRD++LRMYHA +EAL II DI
Sbjct: 288 NVKSFIGSDLLAHLYSN-DQSAMMEESQEEAQRRDEILRMYHATREALTIISDISTTTVS 112
Query: 746 XXXXXXXDDTWLQSASSHSPTPQRRP 771
D WL+ +S +P R P
Sbjct: 111 TPTPPPVKDDWLEPSSGSTPYNGRPP 34
>13952
Length = 577
Score = 34.7 bits (78), Expect = 0.15, Method: Compositional matrix adjust.
Identities = 30/123 (24%), Positives = 59/123 (47%), Gaps = 18/123 (14%)
Frame = -3
Query: 521 IRRGWLTINNISLMKGGS----KEYWFVLTAESLSWYXXXXXXXXXYMLPLDNLKIRDV- 575
++ GWL + +GG K WF+L L ++ ++PL+N+++R++
Sbjct: 419 VKEGWL------MKQGGRYKNWKRRWFILNDNCLYYFQYTADKEPKGIIPLENIQVRELS 258
Query: 576 EKGFMSNKHVFAIFNTEQRNVYK------DLRQIE-------LACDSQEDVDSWKASFLR 622
EK SN F +++ +V K D + +E ++ S E++D+W +S +R
Sbjct: 257 EKSSRSN--AFELYSVSGSDVIKACKVDSDGKVVEGRHSVYRMSASSAEEMDAWISS-IR 87
Query: 623 AGV 625
G+
Sbjct: 86 YGI 78
>14762
Length = 1307
Score = 32.0 bits (71), Expect = 1.0, Method: Composition-based stats.
Identities = 16/36 (44%), Positives = 21/36 (58%)
Frame = +2
Query: 639 QENTFSMDPQLERQVETIRNLVDSYVAIINKSIRDL 674
Q+NT S PQ ERQV R L SY ++++ R L
Sbjct: 1151 QQNTASHAPQQERQVTVQRTLTPSYACKVSRAYRAL 1258
>15376
Length = 712
Score = 32.0 bits (71), Expect = 1.1, Method: Composition-based stats.
Identities = 22/92 (23%), Positives = 45/92 (48%), Gaps = 14/92 (15%)
Frame = +1
Query: 542 WFVLTAESLSWYXXXXXXXXXYMLPLDNLKIRDV-EKGFMSNKHVFAIFNTEQRNVYK-- 598
WF+L L ++ ++PL+N+++R++ EK SN F +++ +V K
Sbjct: 4 WFILNDNCLYYFQYTADKEPKGIIPLENIQVRELSEKSSRSN--AFELYSVSGSDVIKAC 177
Query: 599 ----DLRQIE-------LACDSQEDVDSWKAS 619
D + +E ++ S E++D+W +S
Sbjct: 178 KVDSDGKVVEGRHSVYRMSASSAEEMDAWISS 273
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000285124 | hsapiens_gene_ensembl |
Serine/threonine-protein phosphatase 4 regulatory subunit 1.
[Source:Uniprot/SWISSPROT;Acc:Q8TF05]
(950 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
01469 300 1e-81
25614 172 4e-43
19245 170 3e-42
25537 123 3e-28
19229 117 2e-26
26856 54 4e-07
34109 32 1.7
20201 30 6.1
>01469
Length = 2023
Score = 300 bits (769), Expect = 1e-81, Method: Compositional matrix adjust.
Identities = 155/335 (46%), Positives = 218/335 (65%), Gaps = 3/335 (0%)
Frame = +1
Query: 614 QDVVPQALLDQYLSMTDPSRAQTVDTEIAKHCAYSLPGVALTLGRQNWHCLRETYETLAS 673
QD++PQ+LL+ YL M +PSRAQTVDTEI +HCAY+LP VA TLGRQNWHC++ YETLA
Sbjct: 286 QDIIPQSLLENYLGMVEPSRAQTVDTEITRHCAYNLPAVAYTLGRQNWHCIKHLYETLAQ 465
Query: 674 DMQWKVRRTLAFSIHELAVILGDQLTAADLVPIFNGFLKDLDEVRIGVXXXXXXXXXXXX 733
MQWKVRRTLAFSIHE+A+I G+ +T DL+P+F+GF+KDLDEVRIGV
Sbjct: 466 AMQWKVRRTLAFSIHEMALIEGEAITHNDLLPVFDGFIKDLDEVRIGVLKHLADFLRLLR 645
Query: 734 XXXRREYLYQLQEFLVTDNSRNWRFRXXXXXXXXXXXXXYSPRDVYDYLRPIALNLCADK 793
R++YL ++ +F+ TDN RNWRFR + PR + ++ P+A+ LC DK
Sbjct: 646 PNVRQQYLAKVSDFMKTDNHRNWRFRKELSEQLIYLCELFDPRSIVRHICPLAVALCMDK 825
Query: 794 VSSVRWISYKLVSEMVKKLHAATPPTFGVDLINELVENFGRCPKWSGRQAFVFVCQTVIE 853
V+ VR +S+ L+S +++++H + ++L + F KW GRQ + +C V+
Sbjct: 826 VAEVRAVSFGLMSAVLRRVHEEGEDKLLQVICSDLSDQFALNIKWLGRQIYCQMCLVVLA 1005
Query: 854 DDCLPMDQFAVHLMPHLLTLANDRVPNVRVLLAKTLRQTLLEKDYFLASAS-CHQEAVEQ 912
D+ +P FA L+P LL L D +PNVR+ LAK L Q + DYF +S + CH EA+
Sbjct: 1006DNAVPPPVFAELLLPGLLALGTDAIPNVRLTLAKVLAQRVAPLDYFTSSQNPCH-EALLT 1182
Query: 913 TIMALQMDRDSDVKYFAS--IHPASTKISEDAMST 945
T+ AL+ D+D DV+YF+S + P++T + A T
Sbjct: 1183TLQALKTDKDQDVRYFSSQQVDPSATADVQHAYDT 1287
>25614
Length = 433
Score = 172 bits (437), Expect = 4e-43, Method: Composition-based stats.
Identities = 75/118 (63%), Positives = 96/118 (81%)
Frame = -2
Query: 212 LILPRFCEMCCDCRMFHVRKVCAANFGDICSVVGQQATEEMLLPRFFQLCSDNVWGVRKA 271
++LPRF +M D +FHVRKVCAANFG++CSVVG+Q++EE+LLP+ LC D VWGVRKA
Sbjct: 411 VLLPRFSQMLTD-PLFHVRKVCAANFGEVCSVVGKQSSEELLLPKLNSLCEDGVWGVRKA 235
Query: 272 CAECFMAVSCATCQEIRRTKLSALFINLISDPSRWVRQAAFQSLGPFISTFANPSSSG 329
CAECFMA+SCA E RR L+ LF++L++D SRWVR +AFQ LGPFISTFA+ + +G
Sbjct: 234 CAECFMAISCACSLETRRGYLARLFVHLLADQSRWVRMSAFQHLGPFISTFAHAAHTG 61
>19245
Length = 1339
Score = 170 bits (430), Expect = 3e-42, Method: Compositional matrix adjust.
Identities = 96/276 (34%), Positives = 142/276 (51%), Gaps = 13/276 (4%)
Frame = +2
Query: 448 LDQELYNSFHFWRTPLPEIDLDIELEQNXXXXXXXXXXXXXXXXXXXXXXNITMATRKEL 507
LD +N+F +WR PLP++D+D ++ ++ + K+
Sbjct: 587 LDNCNFNTFQYWRPPLPQVDIDFDVINGAPANIHVVAKVKDEEKHKVYSTHVDVVMSKDS 766
Query: 508 EEMIENLEPHIDDPDVKAQVEVXXXXXXXXXXDAHEETISIEKRSDLQDELD-------- 559
E + I D ++ +++ H T S+ SD + +
Sbjct: 767 AEASASSVHQISDGAMRRDMDLAG---------VHIHTASVSTVSDTDETVSNIGSTNIL 919
Query: 560 INELPNCKINQEDSVPLISD-----AVENMDSTLHYIHXXXXXXXXXXXXPDEERRTKVQ 614
+ L C + D V + D ++ MD+ H + D+ + Q
Sbjct: 920 GDNLGECTLAVVDGV--VKDLSGGSSIGYMDAAHHQV--------------DDSILAQQQ 1051
Query: 615 DVVPQALLDQYLSMTDPSRAQTVDTEIAKHCAYSLPGVALTLGRQNWHCLRETYETLASD 674
D++PQ+LL+ YL M +PSRAQTVDTEI +HCAY+LP VA TLGRQNWHC++ YETLA
Sbjct: 1052DIIPQSLLENYLGMVEPSRAQTVDTEITRHCAYNLPAVAYTLGRQNWHCIKHLYETLAQA 1231
Query: 675 MQWKVRRTLAFSIHELAVILGDQLTAADLVPIFNGF 710
MQWKVRRTLAFSIHE+A+I G+ +T DL+P+F+GF
Sbjct: 1232MQWKVRRTLAFSIHEMALIEGEAITHNDLLPVFDGF 1339
>25537
Length = 487
Score = 123 bits (309), Expect = 3e-28, Method: Composition-based stats.
Identities = 52/81 (64%), Positives = 64/81 (79%)
Frame = +1
Query: 251 EMLLPRFFQLCSDNVWGVRKACAECFMAVSCATCQEIRRTKLSALFINLISDPSRWVRQA 310
E+LLP+F+ LC D VWGVRKACAECFM +SCA E RR L+ LF++L++D SRWVR +
Sbjct: 1 EVLLPKFYNLCGDGVWGVRKACAECFMTISCACSLETRRQYLANLFVDLLADQSRWVRMS 180
Query: 311 AFQSLGPFISTFANPSSSGQY 331
AFQ LGPFISTFA+P +G Y
Sbjct: 181 AFQQLGPFISTFADPRLTGLY 243
Score = 57.4 bits (137), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 29/66 (43%), Positives = 44/66 (66%), Gaps = 9/66 (13%)
Frame = +2
Query: 80 DERDCIAVLERISRLADDSEPTVRAELMEQVPHIALFCQEN--------RPS-IPYAFSK 130
D+ + A+ E +RL+ D+EP+VR+ELMEQVPHIA++CQE RP+ P++F+
Sbjct: 275 DQGEAPALTESGARLSHDAEPSVRSELMEQVPHIAVYCQETKVSSQMPCRPTYCPWSFAI 454
Query: 131 FLLPIV 136
+PI
Sbjct: 455 STMPIT 472
>19229
Length = 470
Score = 117 bits (294), Expect = 2e-26, Method: Compositional matrix adjust.
Identities = 49/77 (63%), Positives = 60/77 (77%)
Frame = -2
Query: 255 PRFFQLCSDNVWGVRKACAECFMAVSCATCQEIRRTKLSALFINLISDPSRWVRQAAFQS 314
P+F+ LC D VWGVRKACAECFM +SCA E RR L+ LF++L++D SRWVR +AFQ
Sbjct: 469 PKFYNLCGDGVWGVRKACAECFMTISCACSLETRRQYLANLFVDLLADQSRWVRMSAFQQ 290
Query: 315 LGPFISTFANPSSSGQY 331
LGPFISTFA+P +G Y
Sbjct: 289 LGPFISTFADPRLTGLY 239
>26856
Length = 2013
Score = 53.5 bits (127), Expect = 4e-07, Method: Compositional matrix adjust.
Identities = 41/159 (25%), Positives = 74/159 (46%), Gaps = 4/159 (2%)
Frame = +1
Query: 169 VETKVCPVLIELTAPDSNDDVKTEAVAIMCKMAPMVGKDITERLILPRFCEM----CCDC 224
+ T + P + +L A D+N VK+ +++ ++P++GKD T +LP F C D
Sbjct: 760 IMTNILPCVKDLVA-DANQHVKSALASVIMGLSPILGKDNTIEHLLPLFLSQLKDECPDV 936
Query: 225 RMFHVRKVCAANFGDICSVVGQQATEEMLLPRFFQLCSDNVWGVRKACAECFMAVSCATC 284
R+ + +N + V+G + + LLP +L D W VR A E ++
Sbjct: 937 RLNII-----SNLDCVNEVIGIKQLSQSLLPAIVELAEDTKWRVRLAIIEYMPLLAGQLG 1101
Query: 285 QEIRRTKLSALFINLISDPSRWVRQAAFQSLGPFISTFA 323
+ KL++L + + D +R+AA +L + F
Sbjct: 1102VQFFDEKLNSLCMTWLVDHVFAIREAATLNLKKLVEKFG 1218
Score = 42.0 bits (97), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 62/261 (23%), Positives = 101/261 (38%), Gaps = 1/261 (0%)
Frame = +1
Query: 671 LASDMQWKVRRTLAFSIHELAVILGDQLTAADLVPIFNGFLKD-LDEVRIGVXXXXXXXX 729
L +D V+ LA I L+ ILG T L+P+F LKD +VR+ +
Sbjct: 793 LVADANQHVKSALASVIMGLSPILGKDNTIEHLLPLFLSQLKDECPDVRLNIISNLDCVN 972
Query: 730 XXXXXXXRREYLYQLQEFLVTDNSRNWRFRXXXXXXXXXXXXXYSPRDVYDYLRPIALNL 789
+ L L D WR R + + L + +
Sbjct: 973 EVIGIKQLSQSLLPAIVELAEDT--KWRVRLAIIEYMPLLAGQLGVQFFDEKLNSLCMTW 1146
Query: 790 CADKVSSVRWISYKLVSEMVKKLHAATPPTFGVDLINELVENFGRCPKWSGRQAFVFVCQ 849
D V ++R + + ++V+K P + + + V + + + R +F
Sbjct: 1147 LVDHVFAIREAATLNLKKLVEKFG----PEWAQETVIPKVTSMSKDSNYLHRMTCLFSIN 1314
Query: 850 TVIEDDCLPMDQFAVHLMPHLLTLANDRVPNVRVLLAKTLRQTLLEKDYFLASASCHQEA 909
+ E + + + L+P LA D VPNVR AKT L+K L S Q
Sbjct: 1315 LLAET--MGQELTSKLLLPTRF-LARDTVPNVRFNAAKT-----LQKIAPLLDQSTVQSQ 1470
Query: 910 VEQTIMALQMDRDSDVKYFAS 930
V+ + L+ D D DV++FA+
Sbjct: 1471 VKPILETLKSDSDIDVQFFAA 1533
Score = 37.4 bits (85), Expect = 0.029, Method: Compositional matrix adjust.
Identities = 21/53 (39%), Positives = 28/53 (52%), Gaps = 1/53 (1%)
Frame = +1
Query: 667 TYETLASDMQWKVRRTLAFSIHELAVILGDQLTAADLVPIFNGFLKDLD-EVR 718
T + D W+VR +A EL +G ++T DLVP F LKD + EVR
Sbjct: 535 TLRQASEDKSWRVRYMVADKFTELQKAVGPEITKNDLVPAFQSLLKDCEAEVR 693
Score = 34.3 bits (77), Expect = 0.26, Method: Compositional matrix adjust.
Identities = 38/176 (21%), Positives = 69/176 (39%), Gaps = 1/176 (0%)
Frame = +1
Query: 128 FSKFLLPIVVRYLADQNNQVRKTSXXXXXXXXXXXXIERFDVE-TKVCPVLIELTAPDSN 186
S+ LLP +V D +VR ++ FD + +C + D
Sbjct: 994 LSQSLLPAIVELAEDTKWRVRLAIIEYMPLLAGQLGVQFFDEKLNSLCMTWL----VDHV 1161
Query: 187 DDVKTEAVAIMCKMAPMVGKDITERLILPRFCEMCCDCRMFHVRKVCAANFGDICSVVGQ 246
++ A + K+ G + + ++P+ M D H R C + + +GQ
Sbjct: 1162 FAIREAATLNLKKLVEKFGPEWAQETVIPKVTSMSKDSNYLH-RMTCLFSINLLAETMGQ 1338
Query: 247 QATEEMLLPRFFQLCSDNVWGVRKACAECFMAVSCATCQEIRRTKLSALFINLISD 302
+ T ++LLP F L D V VR A+ ++ Q ++++ + L SD
Sbjct: 1339 ELTSKLLLPTRF-LARDTVPNVRFNAAKTLQKIAPLLDQSTVQSQVKPILETLKSD 1503
Score = 33.9 bits (76), Expect = 0.34, Method: Compositional matrix adjust.
Identities = 49/222 (22%), Positives = 79/222 (35%), Gaps = 2/222 (0%)
Frame = +1
Query: 664 LRETYETLASDMQWKVRRTLAFSIHELAVILGDQLTAADLVPIFNGFLKD-LDEVR-IGV 721
LR+ + L SD VRR A + E A + + +DL+P+F +D D VR + V
Sbjct: 292 LRQLFRNLCSDDTPMVRRAAAGKLGEFAKEVESEFLKSDLIPLFAMLAQDEQDSVRLLAV 471
Query: 722 XXXXXXXXXXXXXXXRREYLYQLQEFLVTDNSRNWRFRXXXXXXXXXXXXXYSPRDVYDY 781
+ + L++ ++WR R P +
Sbjct: 472 EACVSIASLLPSEDTEQLVMPTLRQ---ASEDKSWRVRYMVADKFTELQKAVGPEITKND 642
Query: 782 LRPIALNLCADKVSSVRWISYKLVSEMVKKLHAATPPTFGVDLINELVENFGRCPKWSGR 841
L P +L D + VR S V + + L T + I V++ +
Sbjct: 643 LVPAFQSLLKDCEAEVRAASANKVKDFCQALSPDVRETIIMTNILPCVKDLVADANQHVK 822
Query: 842 QAFVFVCQTVIEDDCLPMDQFAVHLMPHLLTLANDRVPNVRV 883
A V + L D HL+P L+ D P+VR+
Sbjct: 823 SALASVIMGL--SPILGKDNTIEHLLPLFLSQLKDECPDVRL 942
>34109
Length = 684
Score = 31.6 bits (70), Expect = 1.7, Method: Composition-based stats.
Identities = 17/55 (30%), Positives = 29/55 (52%)
Frame = +1
Query: 617 VPQALLDQYLSMTDPSRAQTVDTEIAKHCAYSLPGVALTLGRQNWHCLRETYETL 671
+P +D+Y +D + AQT+D+ KHC S A T+ HC + + +T+
Sbjct: 457 LPHKKMDRYKKQSDQTSAQTIDSH-QKHCDRS---TAQTIDNHQKHCDQSSTQTI 609
>20201
Length = 557
Score = 29.6 bits (65), Expect = 6.1, Method: Composition-based stats.
Identities = 17/70 (24%), Positives = 33/70 (47%)
Frame = -3
Query: 836 PKWSGRQAFVFVCQTVIEDDCLPMDQFAVHLMPHLLTLANDRVPNVRVLLAKTLRQTLLE 895
P+W + + + ++V+ D L + F VHL P +L P ++++L
Sbjct: 243 PEWFSTEFSLSILKSVLSDPLLAVSNFLVHLTPIILFFFTF*DPQLKLILP--------- 91
Query: 896 KDYFLASASC 905
D+F ++SC
Sbjct: 90 HDHFSFASSC 61
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000367766 | hsapiens_gene_ensembl | X-linked
retinitis pigmentosa GTPase regulator.
[Source:Uniprot/SWISSPROT;Acc:Q92834]
(1152 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
02938 301 1e-81
26574 55 2e-07
20162 54 4e-07
12101 49 1e-05
03352 42 0.001
01451 40 0.008
39525 35 0.15
>02938
Length = 1718
Score = 301 bits (770), Expect = 1e-81, Method: Compositional matrix adjust.
Identities = 165/384 (42%), Positives = 225/384 (58%), Gaps = 1/384 (0%)
Frame = +3
Query: 55 KLYMFGSNNWGQLGLGSKSAISKPTCVKALKPEKVKLAACGRNHTLVSTEGGNVYATGGN 114
+++MFG N++GQLG+G++ ++P+CVK+LK EK +L ACGR+HT+V+TE GN+YA G N
Sbjct: 18 RVFMFGPNDYGQLGIGAQKVANRPSCVKSLKHEKARLVACGRSHTIVATESGNIYAFGAN 197
Query: 115 NEGQLGLGDTEERNTFHVISFFTSEHKIKQLSAGSNTSAALTEDGRLFMWGDNSEGQIGL 174
EGQLG+ E N + + K L+AG + S ALTEDGR+F+WG N EGQ+G+
Sbjct: 198 GEGQLGVEGVTETNLPKQVDSLQAT-PWKMLAAGCDHSLALTEDGRVFVWGGNGEGQLGM 374
Query: 175 KNVSNVCVPQQVTIGKPVSWISCGYYHSAFVTTDGELYVFGEPENGKLGLPNQLLGNHRT 234
S++ VP+Q+ +G+ V+ I+ GYYHSA VT GELY FGE + GKLGL N +T
Sbjct: 375 GEDSDIPVPRQLDVGQSVACIASGYYHSALVTESGELYTFGESDGGKLGL-NGDTDECKT 551
Query: 235 PQLVSEIPEKVIQVACGGEHTVVLTENA-VYXXXXXXXXXXXXXXXXXETSEPKVIENIR 293
PQ V I +KV V+CGG HTV LTE VY E+ P +++
Sbjct: 552 PQQVMAINDKVKSVSCGGSHTVALTEKGEVYAFGEGSSGQLGLGVSTLESESPSLLK--L 725
Query: 294 DQTISYISCGENHTALITDIGLMYTFGDGRHGKLGLGLENFTNHFIPTLCSNFLRFIVKL 353
++ + CGEN T ++++ G +YTFGDGRHGKL LG E+F+N F+ T FL+F VK
Sbjct: 726 PFKVAQVCCGENFTTVVSERGQLYTFGDGRHGKLALGQESFSNQFVCTKVDRFLKFNVKK 905
Query: 354 VACGGCHMVVFAAPHRGVAKEIEFDEINDTCLSVATFLPYSSLTSGNVLQRTLSAXXXXX 413
ACGGCH++V A+P DE + T SLT RT SA
Sbjct: 906 AACGGCHLIVMASPKLENGDVASEDEEEGQIMMNGTIRDSLSLT------RTFSARDRRR 1067
Query: 414 XXXXSPDSFSMRRTLPPIEGTLGL 437
P + RTLPP+ GL
Sbjct: 1068NASPLP----LHRTLPPLGNNRGL 1127
Score = 66.2 bits (160), Expect = 7e-11, Method: Compositional matrix adjust.
Identities = 47/135 (34%), Positives = 66/135 (48%), Gaps = 11/135 (8%)
Frame = +3
Query: 7 LMPDSGAVFTFGKS---KFAEN-------NPGKFWFKNDVPVHLSCGDEHSAVVTGNNKL 56
L+ +SG ++TFG+S K N P + ND +SCG H+ +T ++
Sbjct: 462 LVTESGELYTFGESDGGKLGLNGDTDECKTPQQVMAINDKVKSVSCGGSHTVALTEKGEV 641
Query: 57 YMFGSNNWGQLGLGSKSAISK-PTCVKALKPEKVKLAACGRNHTLVSTEGGNVYATGGNN 115
Y FG + GQLGLG + S+ P+ +K P KV CG N T V +E G +Y G
Sbjct: 642 YAFGEGSSGQLGLGVSTLESESPSLLKL--PFKVAQVCCGENFTTVVSERGQLYTFGDGR 815
Query: 116 EGQLGLGDTEERNTF 130
G+L LG N F
Sbjct: 816 HGKLALGQESFSNQF 860
Score = 47.8 bits (112), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 41/154 (26%), Positives = 71/154 (46%), Gaps = 15/154 (9%)
Frame = +3
Query: 8 MPDSGAVFTFGKSKFAENNPGKFWFKNDVP---------VHLSCGDEHSAVVTGNNKLYM 58
+ + G V+ FG+ + G +++ P + CG+ + VV+ +LY
Sbjct: 621 LTEKGEVYAFGEGSSGQLGLGVSTLESESPSLLKLPFKVAQVCCGENFTTVVSERGQLYT 800
Query: 59 FGSNNWGQLGLGSKSAISKPTCVKALKPEK--VKLAACGRNHTLVST----EGGNVYATG 112
FG G+L LG +S ++ C K + K VK AACG H +V E G+V A+
Sbjct: 801 FGDGRHGKLALGQESFSNQFVCTKVDRFLKFNVKKAACGGCHLIVMASPKLENGDV-ASE 977
Query: 113 GNNEGQLGLGDTEERNTFHVISFFTSEHKIKQLS 146
EGQ+ + T R++ + F++ + + S
Sbjct: 978 DEEEGQIMMNGT-IRDSLSLTRTFSARDRRRNAS 1076
>26574
Length = 441
Score = 55.1 bits (131), Expect = 2e-07, Method: Composition-based stats.
Identities = 32/96 (33%), Positives = 52/96 (54%)
Frame = +3
Query: 59 FGSNNWGQLGLGSKSAISKPTCVKALKPEKVKLAACGRNHTLVSTEGGNVYATGGNNEGQ 118
+G ++ +LG G+ + +P V AL+ +KV ACG H + T+ G V+ G N+EGQ
Sbjct: 6 WGKGDYHRLGHGTDDHVRRPRRVSALQGKKVIDVACGSLHCVACTDSGEVFTWGDNDEGQ 185
Query: 119 LGLGDTEERNTFHVISFFTSEHKIKQLSAGSNTSAA 154
LG G T +++ + KI +++ GS S A
Sbjct: 186 LGDGTTNAIQRPRMVAALQGK-KINRVACGSAHSLA 290
Score = 53.9 bits (128), Expect = 4e-07, Method: Composition-based stats.
Identities = 23/63 (36%), Positives = 39/63 (61%)
Frame = +3
Query: 38 VHLSCGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKSAISKPTCVKALKPEKVKLAACGRN 97
+ ++CG H T + +++ +G N+ GQLG G+ +AI +P V AL+ +K+ ACG
Sbjct: 99 IDVACGSLHCVACTDSGEVFTWGDNDEGQLGDGTTNAIQRPRMVAALQGKKINRVACGSA 278
Query: 98 HTL 100
H+L
Sbjct: 279 HSL 287
Score = 47.4 bits (111), Expect = 3e-05, Method: Composition-based stats.
Identities = 23/64 (35%), Positives = 36/64 (56%), Gaps = 2/64 (3%)
Frame = +3
Query: 141 KIKQLSAGSNTSAALTEDGRLFMWGDNSEGQIGLKNVSNVCVPQQVTI--GKPVSWISCG 198
K+ ++ GS A T+ G +F WGDN EGQ+G + + P+ V GK ++ ++CG
Sbjct: 93 KVIDVACGSLHCVACTDSGEVFTWGDNDEGQLGDGTTNAIQRPRMVAALQGKKINRVACG 272
Query: 199 YYHS 202
HS
Sbjct: 273 SAHS 284
Score = 41.2 bits (95), Expect = 0.002, Method: Composition-based stats.
Identities = 23/87 (26%), Positives = 43/87 (49%)
Frame = +3
Query: 286 PKVIENIRDQTISYISCGENHTALITDIGLMYTFGDGRHGKLGLGLENFTNHFIPTLCSN 345
P+ + ++ + + ++CG H TD G ++T+GD G+LG G N P + +
Sbjct: 63 PRRVSALQGKKVIDVACGSLHCVACTDSGEVFTWGDNDEGQLGDGTTNAIQR--PRMVAA 236
Query: 346 FLRFIVKLVACGGCHMVVFAAPHRGVA 372
+ VACG H + ++ H+ V+
Sbjct: 237 LQGKKINRVACGSAHSLAWST-HKPVS 314
Score = 33.9 bits (76), Expect = 0.39, Method: Composition-based stats.
Identities = 19/76 (25%), Positives = 34/76 (44%), Gaps = 1/76 (1%)
Frame = +3
Query: 233 RTPQLVSEIP-EKVIQVACGGEHTVVLTENAVYXXXXXXXXXXXXXXXXXETSEPKVIEN 291
R P+ VS + +KVI VACG H V T++ P+++
Sbjct: 57 RRPRRVSALQGKKVIDVACGSLHCVACTDSGEVFTWGDNDEGQLGDGTTNAIQRPRMVAA 236
Query: 292 IRDQTISYISCGENHT 307
++ + I+ ++CG H+
Sbjct: 237 LQGKKINRVACGSAHS 284
>20162
Length = 1121
Score = 53.5 bits (127), Expect = 4e-07, Method: Compositional matrix adjust.
Identities = 61/246 (24%), Positives = 95/246 (38%), Gaps = 30/246 (12%)
Frame = +1
Query: 45 EHSAVVTGNNKLYMFGSNNWGQLGLGSKSAI----SKPTCVKALKPEKVKL--------- 91
E S + N LY FG +GQLG S +K + P KV +
Sbjct: 109 EFSTMSDINGNLYSFGCPEYGQLGHNSDGKYFVTSNKMEYKCEMTPRKVSVFIEKTRDGH 288
Query: 92 -----------AACGRNHTLVSTEGGNVYATGGNNEGQLGLGDTEERNTFHVISFFTSEH 140
ACG NHTL+ +++ G G+LG + ++ +I FF
Sbjct: 289 VMPITDVDIREVACGLNHTLIMDSKKRLFSWGFGGYGRLGHAEPKDELVPRLIKFFDGPG 468
Query: 141 K-IKQLSAGSNTSAALTEDGRLFMWGDN---SEGQIGLKNVSNVCVPQQVTIGKPVSWIS 196
+ Q+ GS+ + E G L+ WG + E + K V ++ G V I
Sbjct: 469 RGGSQIQCGSSFCMTVNEHGALYFWGQSKPTGEATMYPKLVQDLS-------GWKVRSIG 627
Query: 197 CGYYHSAFVTTDGELYVFG-EPENGKLGLPNQLLGNHRTPQLVSEIPEKVIQ-VACGGEH 254
C Y S + D + +G P G+LG + + Q V + + VACG H
Sbjct: 628 CC-YRSIVLCADDSVVSWGPSPTYGELGYGENKMKSSTVAQEVKPLDGVYVHDVACGYAH 804
Query: 255 TVVLTE 260
T+++
Sbjct: 805 TLMIAR 822
Score = 31.2 bits (69), Expect = 2.5, Method: Compositional matrix adjust.
Identities = 13/37 (35%), Positives = 23/37 (62%)
Frame = +1
Query: 292 IRDQTISYISCGENHTALITDIGLMYTFGDGRHGKLG 328
I D I ++CG NHT ++ ++++G G +G+LG
Sbjct: 298 ITDVDIREVACGLNHTLIMDSKKRLFSWGFGGYGRLG 408
Score = 29.6 bits (65), Expect = 6.9, Method: Compositional matrix adjust.
Identities = 36/183 (19%), Positives = 67/183 (36%), Gaps = 12/183 (6%)
Frame = +1
Query: 195 ISCGYYHSAFVTTDGELYVFGEPENGKLGLPNQLLGNHRTPQLVSEIPEKVI-------- 246
++CG H+ + + L+ +G G+LG H P+ E+ ++I
Sbjct: 322 VACGLNHTLIMDSKKRLFSWGFGGYGRLG--------HAEPK--DELVPRLIKFFDGPGR 471
Query: 247 ---QVACGGEHTVVLTEN-AVYXXXXXXXXXXXXXXXXXETSEPKVIENIRDQTISYISC 302
Q+ CG + + E+ A+Y T PK+++++ + I C
Sbjct: 472 GGSQIQCGSSFCMTVNEHGALYFWGQSKPTGEA-------TMYPKLVQDLSGWKVRSIGC 630
Query: 303 GENHTALITDIGLMYTFGDGRHGKLGLGLENFTNHFIPTLCSNFLRFIVKLVACGGCHMV 362
L D ++ +G+LG G + + V VACG H +
Sbjct: 631 CYRSIVLCADDSVVSWGPSPTYGELGYGENKMKSSTVAQEVKPLDGVYVHDVACGYAHTL 810
Query: 363 VFA 365
+ A
Sbjct: 811 MIA 819
>12101
Length = 1020
Score = 48.9 bits (115), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 46/160 (28%), Positives = 69/160 (43%), Gaps = 9/160 (5%)
Frame = -2
Query: 56 LYMFGSNNWGQLGLGSKSAISKPTCVKALKPEK-----VKLAACGRNHTLVSTEGGNVYA 110
++ G NN+ QL ++ + L P K VK A G++HTL+ A
Sbjct: 860 IWAVGLNNYKQLAHPKETE-------RFLTPVKTEIKDVKQIAGGQHHTLILDNNMRCLA 702
Query: 111 TGGNNEGQLGLGDTEERNTFHVISFFTSEHKIKQLSAGSNTSAALTEDGRLFMWGDNSEG 170
G G+LGLG E T + K+ ++ G S +T DG+L+ WG S
Sbjct: 701 VGRPEYGRLGLGKVTEVVT-KPTAITQLNGKVNYVACGEACSFXITNDGKLYSWGMGSLL 525
Query: 171 QIGLKNVSNVCVPQQV----TIGKPVSWISCGYYHSAFVT 206
Q+G+ + + VP +V T K V G HS F+
Sbjct: 524 QLGVGDGDDEVVPVEVSSKNTQNKKVLLADGGGQHSVFLV 405
Score = 48.5 bits (114), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 46/161 (28%), Positives = 75/161 (46%), Gaps = 5/161 (3%)
Frame = -2
Query: 108 VYATGGNNEGQLGLGDTEERNTFHVISFFTSEHKIKQLSAGSNTSAALTEDGRLFMWGDN 167
++A G NN QL ER + T +KQ++ G + + L + R G
Sbjct: 860 IWAVGLNNYKQLAHPKETER---FLTPVKTEIKDVKQIAGGQHHTLILDNNMRCLAVGRP 690
Query: 168 SEGQIGLKNVSNVCV-PQQVT-IGKPVSWISCGYYHSAFVTTDGELYVFGEPENGKLGLP 225
G++GL V+ V P +T + V++++CG S +T DG+LY +G +LG+
Sbjct: 689 EYGRLGLGKVTEVVTKPTAITQLNGKVNYVACGEACSFXITNDGKLYSWGMGSLLQLGVG 510
Query: 226 NQLLGNHRTPQLVSEI---PEKVIQVACGGEHTVVLTENAV 263
+ + P VS +KV+ GG+H+V L E V
Sbjct: 509 DG--DDEVVPVEVSSKNTQNKKVLLADGGGQHSVFLVEADV 393
Score = 35.8 bits (81), Expect = 0.11, Method: Compositional matrix adjust.
Identities = 33/123 (26%), Positives = 54/123 (43%), Gaps = 3/123 (2%)
Frame = -2
Query: 245 VIQVACGGEHTVVLTENAVYXXXXXXXXXXXXXXXXXET-SEPKVIENIRDQTISYISCG 303
V Q+A G HT++L N E ++P I + + ++Y++CG
Sbjct: 767 VKQIAGGQHHTLILDNNMRCLAVGRPEYGRLGLGKVTEVVTKPTAITQLNGK-VNYVACG 591
Query: 304 ENHTALITDIGLMYTFGDGRHGKLGLGLENFTNHFIPTLCS--NFLRFIVKLVACGGCHM 361
E + IT+ G +Y++G G +LG+G + + +P S N V L GG H
Sbjct: 590 EACSFXITNDGKLYSWGMGSLLQLGVG--DGDDEVVPVEVSSKNTQNKKVLLADGGGQHS 417
Query: 362 VVF 364
V
Sbjct: 416 VFL 408
Score = 32.3 bits (72), Expect = 1.2, Method: Compositional matrix adjust.
Identities = 22/69 (31%), Positives = 35/69 (50%), Gaps = 2/69 (2%)
Frame = -2
Query: 39 HLSCGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKSAISKPTCV--KALKPEKVKLAACGR 96
+++CG+ S +T + KLY +G + QLG+G P V K + +KV LA G
Sbjct: 605 YVACGEACSFXITNDGKLYSWGMGSLLQLGVGDGDDEVVPVEVSSKNTQNKKVLLADGGG 426
Query: 97 NHTLVSTEG 105
H++ E
Sbjct: 425 QHSVFLVEA 399
>03352
Length = 935
Score = 42.4 bits (98), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 37/130 (28%), Positives = 55/130 (42%), Gaps = 16/130 (12%)
Frame = +2
Query: 7 LMPDSGAVFTFGKSKFAEN---------------NPGKFW-FKNDVPVHLSCGDEHSAVV 50
++ D G+VF G +K E+ P K +N V ++C SAVV
Sbjct: 80 MLADDGSVFFVGLAKRGEDGDSGAAKGRRQPKSVKPKKMIRVENKQVVFVACNSGSSAVV 259
Query: 51 TGNNKLYMFGSNNWGQLGLGSKSAISKPTCVKALKPEKVKLAACGRNHTLVSTEGGNVYA 110
T + ++YMFG + + V LK V A G+ HT+ T G ++
Sbjct: 260 TKDGEVYMFGKD--------TSHCDHASGHVTDLKDVVVTQVALGKAHTVALTSKGQLFT 415
Query: 111 TGGNNEGQLG 120
G NN+GQ G
Sbjct: 416 FGINNKGQCG 445
Score = 42.0 bits (97), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 38/134 (28%), Positives = 60/134 (44%), Gaps = 10/134 (7%)
Frame = +2
Query: 136 FTSEHKIKQLSAGSNTSAAL--TEDGRLFMWGDNSEGQ-------IGLKNVSNVCVPQQV 186
T KI+Q++ G + AL +DG +F G G+ G + +V + +
Sbjct: 20 ITKSPKIQQVATGHEGAHALMLADDGSVFFVGLAKRGEDGDSGAAKGRRQPKSVKPKKMI 199
Query: 187 TI-GKPVSWISCGYYHSAFVTTDGELYVFGEPENGKLGLPNQLLGNHRTPQLVSEIPEKV 245
+ K V +++C SA VT DGE+Y+FG+ + +H + + V
Sbjct: 200 RVENKQVVFVACNSGSSAVVTKDGEVYMFGK---------DTSHCDHASGHVTDLKDVVV 352
Query: 246 IQVACGGEHTVVLT 259
QVA G HTV LT
Sbjct: 353 TQVALGKAHTVALT 394
Score = 36.2 bits (82), Expect = 0.076, Method: Compositional matrix adjust.
Identities = 32/137 (23%), Positives = 56/137 (40%), Gaps = 9/137 (6%)
Frame = +2
Query: 201 HSAFVTTDGELYVFGEPENGKLGLPNQLLGNHRTPQLVSEIPEKVIQV--------AC-G 251
H+ + DG ++ G + G+ G G R P+ V P+K+I+V AC
Sbjct: 71 HALMLADDGSVFFVGLAKRGEDGDSGAAKG-RRQPKSVK--PKKMIRVENKQVVFVACNS 241
Query: 252 GEHTVVLTENAVYXXXXXXXXXXXXXXXXXETSEPKVIENIRDQTISYISCGENHTALIT 311
G VV + VY + +++D ++ ++ G+ HT +T
Sbjct: 242 GSSAVVTKDGEVYMFGKDTSHCDHASGH---------VTDLKDVVVTQVALGKAHTVALT 394
Query: 312 DIGLMYTFGDGRHGKLG 328
G ++TFG G+ G
Sbjct: 395 SKGQLFTFGINNKGQCG 445
>01451
Length = 1229
Score = 39.7 bits (91), Expect = 0.008, Method: Compositional matrix adjust.
Identities = 18/49 (36%), Positives = 27/49 (55%)
Frame = -3
Query: 289 IENIRDQTISYISCGENHTALITDIGLMYTFGDGRHGKLGLGLENFTNH 337
IE + D + I+ G +H A +TD+G +YT G G+LG E F+
Sbjct: 1179 IEVLPDAVVVKIASGSDHIACLTDLGELYTLGCAEQGQLGRVAECFSTR 1033
>39525
Length = 450
Score = 35.4 bits (80), Expect = 0.15, Method: Composition-based stats.
Identities = 13/38 (34%), Positives = 27/38 (71%), Gaps = 2/38 (5%)
Frame = -3
Query: 141 KIKQLSAGSNTS--AALTEDGRLFMWGDNSEGQIGLKN 176
K++ +++G N A+T++G+++ WG N +GQ+GL +
Sbjct: 163 KVRTIASGCNACHCVAITDEGKVYTWGRNEKGQLGLSD 50
Score = 31.2 bits (69), Expect = 2.9, Method: Composition-based stats.
Identities = 17/41 (41%), Positives = 24/41 (58%)
Frame = -3
Query: 289 IENIRDQTISYISCGENHTALITDIGLMYTFGDGRHGKLGL 329
+E I+ +TI+ C H ITD G +YT+G G+LGL
Sbjct: 175 LEGIKVRTIAS-GCNACHCVAITDEGKVYTWGRNEKGQLGL 56
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000337825 | hsapiens_gene_ensembl | Proto-oncogene
tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK) (Lymphocyte
cell-specific protein-tyrosine kinase) (LSK) (T cell- specific
protein-tyrosine kinase). [Source:Uniprot/SWISSPROT;Acc:P06239]
(509 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
06405 298 2e-81
21808 283 4e-77
11780 206 7e-73
04852 161 5e-40
09007 157 7e-39
07291 138 5e-33
17300 122 3e-31
20640 124 8e-29
14116 121 7e-28
07940 110 1e-24
18996 107 9e-24
17637 105 5e-23
22005 84 7e-23
08294 104 1e-22
14477 94 1e-19
01718 91 1e-18
19301 86 4e-17
13305 84 1e-16
13592 78 9e-15
18921 77 1e-14
12721 77 1e-14
07833 77 2e-14
01060 76 3e-14
29581 75 6e-14
17253 73 3e-13
14126 72 4e-13
01707 72 6e-13
01756 69 6e-12
00300 68 8e-12
00715 67 2e-11
01966 65 6e-11
14420 65 9e-11
27546 64 1e-10
18484 63 2e-10
12672 63 2e-10
25550 60 1e-09
04591 60 2e-09
07836 59 3e-09
31885 57 2e-08
17975 57 3e-08
13066 56 3e-08
19094 55 7e-08
09606 55 9e-08
03240 54 1e-07
21079 51 1e-06
30755 51 1e-06
15910 50 3e-06
04138 49 4e-06
13212 49 4e-06
26711 47 2e-05
35671 47 3e-05
01392 45 5e-05
19761 45 7e-05
16708 45 8e-05
37602 44 1e-04
26560 44 1e-04
27405 42 5e-04
11185 42 6e-04
21433 42 7e-04
12786 40 0.002
18481 40 0.002
28638 40 0.002
17286 40 0.003
29243 40 0.003
32264 39 0.003
27287 37 0.018
21210 37 0.022
32000 36 0.031
36481 36 0.032
07933 35 0.049
38046 35 0.11
20559 34 0.11
29590 34 0.17
11228 33 0.27
37260 33 0.39
15741 32 0.53
13664 32 0.63
06462 31 1.2
20131 31 1.3
32357 31 1.4
25100 29 5.4
18050 29 5.8
17516 28 6.8
30665 28 8.0
>06405
Length = 1965
Score = 298 bits (764), Expect = 2e-81, Method: Compositional matrix adjust.
Identities = 161/352 (45%), Positives = 229/352 (65%), Gaps = 8/352 (2%)
Frame = +1
Query: 155 ESESTAGSFSLSVRDFDQNQGEVVKHYKIRNLDNGGFYISPRITFPGLHELVRHYTNASD 214
ESES+ G S+SVR F+ V HY+I D+G +++ F L ELV H++ +D
Sbjct: 1 ESESSPGQRSISVR-FEGR----VYHYRITE-DDGKVFVTQEHRFNTLAELVHHHSIHAD 162
Query: 215 GLCTRLSRPCQTQKPQKPWW------EDEWEVPRETLKLVERLGAGQFGEVWMGYYNGHT 268
GL T L P K QKP D WE+ R + + RLG GQ+G+V+ + +
Sbjct: 163 GLVTTLLYPAP--KRQKPTVFGVSPEPDRWEIERTEIAMKHRLGGGQYGDVYEAMWKRYN 336
Query: 269 K-VAVKSLKQGSMSPDAFLAEANLMKQLQHQRLVRLYAVVTQEP-IYIITEYMENGSLVD 326
K VAVK+LK+ +M+ + FL EA +MK+++H LV+L V T+EP YI+TE+M +G+L+D
Sbjct: 337 KIVAVKTLKEDTMALNDFLEEAAIMKEMKHPNLVQLLGVCTREPPFYIVTEFMPHGNLLD 516
Query: 327 FLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLA 386
+L++ + + L+ MA QIA GMA++E +N+IHRDL A N LV+D+ K+ADFGLA
Sbjct: 517 YLRSSTREENGPTALMYMATQIASGMAYLETKNFIHRDLAARNCLVADSNMVKVADFGLA 696
Query: 387 RLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTN 446
RL++D+ YTA GAKFPIKWTAPE + + F+ +SD+W+FG+LL E+ T+G PYPG+
Sbjct: 697 RLMKDDTYTAHIGAKFPIKWTAPEGLAFNRFSTRSDIWAFGVLLWELATYGMSPYPGVEL 876
Query: 447 PEVIQNLERGYRMVRPDNCPEELYQLMRLCWKERPEDRPTFDYLRSVLEDFF 498
EV LERGYRM RP P ++Y LM CW+ P+DRPTF + +LE+ F
Sbjct: 877 TEVYHLLERGYRMERPPGTPADVYILMLKCWQWDPKDRPTFKEIHFLLENMF 1032
>21808
Length = 1011
Score = 283 bits (725), Expect(2) = 4e-77, Method: Compositional matrix adjust.
Identities = 138/225 (61%), Positives = 175/225 (77%), Gaps = 1/225 (0%)
Frame = +1
Query: 262 GYYNGHTKVAVKSLKQGSMSPDAFLAEANLMKQLQHQRLVRLYAVVTQE-PIYIITEYME 320
G +N T VA+K+LK G+M P FLAEA +MK+L+H +L++LYAV TQ+ PI+IITE M+
Sbjct: 4 GLWNNTTPVAIKTLKSGTMDPKDFLAEAQIMKKLRHPKLIQLYAVCTQDDPIFIITELMK 183
Query: 321 NGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKI 380
NGSL++FL+ G L + L+D+ AQIA GMA++E +NYIHRDL A NILVSD + KI
Sbjct: 184 NGSLLEFLQG-KGRVLKLPALIDIGAQIACGMAYLESQNYIHRDLAARNILVSDNNTVKI 360
Query: 381 ADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIP 440
ADFGLAR+I+++EY AR GA+FPIKWTAPEA NY FTIKSDVWSFGILLTE VT+GR+P
Sbjct: 361 ADFGLARVIKEDEYEARVGARFPIKWTAPEAANYNRFTIKSDVWSFGILLTETVTYGRVP 540
Query: 441 YPGMTNPEVIQNLERGYRMVRPDNCPEELYQLMRLCWKERPEDRP 485
YPGMTN EV+ +E GYRM P CP+ LY +M CW++ +RP
Sbjct: 541 YPGMTNAEVLHQVEHGYRMPCPPGCPKPLYDIMLECWRKEEMERP 675
Score = 23.1 bits (48), Expect(2) = 4e-77, Method: Compositional matrix adjust.
Identities = 10/22 (45%), Positives = 14/22 (63%)
Frame = +2
Query: 485 PTFDYLRSVLEDFFTATEGQYQ 506
PTF+ L+ LE+FFT Y+
Sbjct: 674 PTFETLQWKLEEFFTMDSKDYR 739
>11780
Length = 1713
Score = 206 bits (523), Expect(2) = 7e-73, Method: Compositional matrix adjust.
Identities = 126/341 (36%), Positives = 189/341 (55%), Gaps = 10/341 (2%)
Frame = +3
Query: 82 FEKGEQLRILEQSGE--WWKAQSLTTGQEGFIPFNFVA--KANSLEPEPWFFKNLSRKDA 137
F+KG+ L I + + W+KA + G+EG IP N+V K +L PWF ++R+ A
Sbjct: 111 FQKGDLLVIRRATSDRMWYKACD-SNGREGMIPANYVQPRKVVTLHAMPWFHGKITRQQA 287
Query: 138 ERQLLAPGNTHGSFLIRESESTAGSFSLSVRDFDQNQGEVVKHYKIRNLDNGGFYISPRI 197
E +LL P G FLIRES + G ++L V + V+HY+I +N I
Sbjct: 288 E-ELLKP-REDGLFLIRESSNYPGDYTLCVCHLGK-----VEHYRILYRENQ-LTIDEEG 443
Query: 198 TFPGLHELVRHYTNASDGLCTRLSRPCQTQKPQ------KPWWEDEWEVPRETLKLVERL 251
F L ELV+HY +DGLCT+L+RP Q + + W + + L++ E +
Sbjct: 444 FFRNLDELVKHYLADADGLCTQLTRPVTKQGGNFGTVSLQEFKSGGWVIAXQDLEIGEAI 623
Query: 252 GAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPDAFLAEANLMKQLQHQRLVRLYAVVTQEP 311
G G FG+V+ G Y G VA+K LK +FL EA++M L+H LVRL VV E
Sbjct: 624 GKGDFGDVYKGMYRGQP-VAIKQLKDKDRGEQSFLQEASVMTSLRHDNLVRLIGVVLGET 800
Query: 312 IYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANIL 371
I+++TE+M G+LV++L++ +T ++ A M ++E + +HRDL A N+L
Sbjct: 801 IFLVTEFMGKGNLVEYLRSRGRSVITKKDQINFATDTCAAMEYLESKRLVHRDLAARNVL 980
Query: 372 VSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAI 412
V D K++DFGLA+ + ++ + KFPIKWTAPEA+
Sbjct: 981 VHDDGKAKVSDFGLAKFGDFSQTS----VKFPIKWTAPEAL 1091
Score = 87.0 bits (214), Expect(2) = 7e-73, Method: Compositional matrix adjust.
Identities = 39/80 (48%), Positives = 56/80 (70%)
Frame = +1
Query: 417 FTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDNCPEELYQLMRLC 476
FT KSD+WSFGILL EI + GR+PYP + +V+ ++ERGYRM P+ CP E+Y +M+
Sbjct: 1105 FTSKSDMWSFGILLWEIYSFGRVPYPRIPLTDVVMHVERGYRMEAPEGCPPEIYSIMKQA 1284
Query: 477 WKERPEDRPTFDYLRSVLED 496
W+ P +RPTF + + L +
Sbjct: 1285 WELDPNERPTFKSVLARLNN 1344
>04852
Length = 1462
Score = 161 bits (408), Expect = 5e-40, Method: Compositional matrix adjust.
Identities = 98/254 (38%), Positives = 133/254 (52%), Gaps = 31/254 (12%)
Frame = +1
Query: 268 TKVAVKSLKQ--GSMSPDAFLAEANLMKQLQ----HQRLVRLYAVVTQE-PIYIITEYME 320
+ VAVK L+ ++ F+ E +MK ++ H +V TQ P+++I E+ +
Sbjct: 22 STVAVKMLRDIVTAVEEQDFVQELQVMKAVKKMGSHINIVNFLGCCTQGGPLWVIVEFAK 201
Query: 321 NGSLVDFL-----------------------KTPSGIKLTINKLLDMAAQIAEGMAFIEE 357
NG+L DFL KTP G + LL A QIA GM F+
Sbjct: 202 NGNLRDFLESCRDGINGYGKFVSPQDPGWYTKTPGGHVIRRKNLLSYAFQIARGMEFLAS 381
Query: 358 RNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTF 417
R IHRDL A N+LV++ KIADFGL+R + Y R G + P+KW APEA+ +
Sbjct: 382 RKCIHRDLAARNVLVTEEHVLKIADFGLSR--TGDYYKKRSGGRLPVKWMAPEALFDMRY 555
Query: 418 TIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQN-LERGYRMVRPDNCPEELYQLMRLC 476
T KSDVWSFG++L EI + G +PY + N E+ L+ YRM RP+ LY +M C
Sbjct: 556 TTKSDVWSFGVVLWEIFSLGGMPYASIPNEELYSKLLDDAYRMPRPELASGNLYAIMERC 735
Query: 477 WKERPEDRPTFDYL 490
W RP DRP F L
Sbjct: 736 WLNRPSDRPEFSQL 777
>09007
Length = 1440
Score = 157 bits (398), Expect = 7e-39, Method: Compositional matrix adjust.
Identities = 88/266 (33%), Positives = 145/266 (54%), Gaps = 15/266 (5%)
Frame = -1
Query: 240 VPRETLKLVERLGAGQFGEV----WMGYYNGHTKVAVKSLKQGSMSPDA--FLAEANLMK 293
+ ++ + L + LG G FG V W +VAVK L + + D FL E +M+
Sbjct: 888 ISKDCVALSKSLGQGHFGTVRQAIWTAESGEKVQVAVKCLSKDKIHKDGQEFLKETAIMQ 709
Query: 294 QLQHQRLVRLYAVVTQE--PIYIITEYMENGSLVDFLKTPSG-IKLTINKLLDMAAQIAE 350
L H+ +VR+Y VV I ++TE SL++ +K S + ++ +L D + Q+ +
Sbjct: 708 MLDHENIVRVYGVVMDNGADIMLVTELAPMRSLLECVKEVSARVDFSVPRLCDFSQQVCD 529
Query: 351 GMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLA-RLIEDNEYTAREGA---KFPIKW 406
GM+++E + +HRDL A NIL+ KI+D G++ L EY + + + W
Sbjct: 528 GMSYLESKRLVHRDLAARNILLFSKSKVKISDVGVSGALGAGKEYYQSQQTIHLQNAVAW 349
Query: 407 TAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLE--RGYRMVRPDN 464
APE+ F+ SDVW+FG+LL E THG P+ G+ ++++ ++ + R+ +PD
Sbjct: 348 CAPESFRNLCFSSASDVWAFGVLLWEFFTHGFQPWAGLNGQQIMEAVDAPQSQRLEQPDL 169
Query: 465 CPEELYQLMRLCWKERPEDRPTFDYL 490
CP+E Y +M CW++ P+ RPTF L
Sbjct: 168 CPKEYYAVMLKCWEQEPQRRPTFSQL 91
>07291
Length = 833
Score = 138 bits (348), Expect = 5e-33, Method: Compositional matrix adjust.
Identities = 67/164 (40%), Positives = 104/164 (63%), Gaps = 2/164 (1%)
Frame = +1
Query: 336 LTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLA-RLIEDNEY 394
LT+ +LLD QIA+GMA+++E +HR+L A N +V++ +++D+G+ L + Y
Sbjct: 40 LTVVQLLDFGRQIADGMAYLQEVKVVHRNLAARNCIVTEDGRLQLSDYGVTGSLFPQSYY 219
Query: 395 TAREG-AKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNL 453
TA + A+ +KW APE I+ F+ KSDVW+FG++L E++T G PYP + N ++ L
Sbjct: 220 TADDSPARDLVKWMAPETIDNFHFSSKSDVWAFGVVLWELLTRGITPYPDVENSSLLPYL 399
Query: 454 ERGYRMVRPDNCPEELYQLMRLCWKERPEDRPTFDYLRSVLEDF 497
+ G+RM +P PE +Y++M CW E PE RP F L L+ F
Sbjct: 400 KEGHRMKKPKQSPEPVYEMMTACWNESPEQRPDFAELNDQLKTF 531
>17300
Length = 480
Score = 122 bits (307), Expect(2) = 3e-31, Method: Compositional matrix adjust.
Identities = 57/116 (49%), Positives = 82/116 (70%), Gaps = 4/116 (3%)
Frame = +1
Query: 348 IAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDN----EYTAREGAKFP 403
I+ GM + + Y+HRDL A NILV++ L CK+ADFGL+R IE + YT + G K P
Sbjct: 1 ISSGMGXLADMGYVHRDLAARNILVNEILVCKVADFGLSREIESDTTEGAYTTK-GGKIP 177
Query: 404 IKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRM 459
++WTAPEAI Y FT SDVWSFG+++ E++++G PY +N +VI+ +E+GYR+
Sbjct: 178 VRWTAPEAIAYRKFTSASDVWSFGVVMWEVMSYGERPYWNWSNQDVIKAVEKGYRL 345
Score = 30.8 bits (68), Expect(2) = 3e-31, Method: Composition-based stats.
Identities = 13/39 (33%), Positives = 19/39 (48%)
Frame = +2
Query: 464 NCPEELYQLMRLCWKERPEDRPTFDYLRSVLEDFFTATE 502
+CPE L+QLM W++ RP + L+ A E
Sbjct: 356 DCPEALHQLMLDAWQKERSHRPKMSMVVKTLDKLIRAPE 472
>20640
Length = 1492
Score = 124 bits (311), Expect = 8e-29, Method: Compositional matrix adjust.
Identities = 61/146 (41%), Positives = 84/146 (57%), Gaps = 1/146 (0%)
Frame = +1
Query: 358 RNYIHRDLRAANILVSDTLSCKIADFGLARLIED-NEYTAREGAKFPIKWTAPEAINYGT 416
R Y+HRDL N LV L KI+DFGLAR + + Y E PI+W EAI Y
Sbjct: 1 RGYVHRDLATRNCLVGHDLVVKISDFGLARSVHSVDYYRGSEHDAIPIRWMPLEAILYNK 180
Query: 417 FTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDNCPEELYQLMRLC 476
F+ +SDVWSFG++L EI PY G+T+ EV++ ++ G + P+ P +Y+LM+ C
Sbjct: 181 FSTQSDVWSFGVVLWEIFAFALQPYYGLTHEEVVRFVKEGKVLACPERTPPPMYELMKQC 360
Query: 477 WKERPEDRPTFDYLRSVLEDFFTATE 502
W RP RP+F L LE+ + E
Sbjct: 361 WHRRPATRPSFHTLHKTLENMHSKYE 438
>14116
Length = 1017
Score = 121 bits (303), Expect = 7e-28, Method: Compositional matrix adjust.
Identities = 72/216 (33%), Positives = 117/216 (54%), Gaps = 13/216 (6%)
Frame = -1
Query: 240 VPRETLKLVERLGAGQFGEVWMGYYN-----GHTKVAVKSLKQGS---MSPDAFLAEANL 291
+ RE L + E +G G FG V G+ G VAVK+L + + +FL EA +
Sbjct: 645 IDREFLTMGEEIGKGNFGCVKRGFLTLPEQKGDILVAVKTLHNNNPREIELQSFLQEALI 466
Query: 292 MKQLQHQRLVRLYAV---VTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQI 348
MK H ++ L + + P+ ++ +M++G L+ +++ + TI L+ I
Sbjct: 465 MKDFHHSNVLTLIGICLNLDDMPL-VVLPFMKHGDLLTYIRDDQH-QPTIKDLIMYGVDI 292
Query: 349 AEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREG--AKFPIKW 406
A GM ++ ++HRDL A N ++ + K+ADFGLAR I + EY + E AK P+KW
Sbjct: 291 ARGMDYLAGLKFVHRDLAARNCMLDEDFHVKVADFGLARDIYEKEYYSSENKKAKLPVKW 112
Query: 407 TAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYP 442
A E++ G + K+DVWS+G++L E++T G P
Sbjct: 111 MALESLEKGNYDSKTDVWSYGVVLWELLTRGSDALP 4
>07940
Length = 1336
Score = 110 bits (276), Expect = 1e-24, Method: Compositional matrix adjust.
Identities = 84/278 (30%), Positives = 127/278 (45%), Gaps = 70/278 (25%)
Frame = -3
Query: 237 EWEVPRETLKLVERLGAGQFGEVW----MGYY--NGHTKVAVKSLKQGSMSPDA--FLAE 288
+WE PRE L L +RLG G FG V MG + N VAVK LK+ + + + E
Sbjct: 860 KWEFPRERLVLGDRLGEGAFGLVMKGEAMGIFKDNNSVTVAVKMLKEDATDREMMDLIRE 681
Query: 289 ANLMKQL-QHQRLVRL----------YAVVTQEPIYIITEYMEN---------------- 321
+MK + +H+ ++ L Y +V P + +++++
Sbjct: 680 MEMMKVIGKHKNIINLLGCCTQRGALYVIVEFAPHGNLRDFLKSHRPHGTSYSCIADYEQ 501
Query: 322 ---------------------GSLVDFLKTPSGIK-------------LTINKLLDMAAQ 347
G+ + F+ S + LT L+ A Q
Sbjct: 500 PVITSSSSSFSHPNSASSSAQGTSLGFIPGTSTVSFSTGSHRQDMLKMLTPKDLISYAYQ 321
Query: 348 IAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTARE-GAKFPIKW 406
+A GM ++ + IHRDL A N+LV++ KIADFGL R ++ +Y + + P+KW
Sbjct: 320 VARGMEYLASKQCIHRDLAARNVLVAEEYVLKIADFGLTRNLQQFDYYRKTTDGRLPVKW 141
Query: 407 TAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGM 444
APEA+ +T KSDVWS+G+LL EI T G PYP +
Sbjct: 140 MAPEALFDRKYTSKSDVWSYGVLLWEIFTLGGNPYPSV 27
>18996
Length = 491
Score = 107 bits (268), Expect = 9e-24, Method: Compositional matrix adjust.
Identities = 65/158 (41%), Positives = 87/158 (55%), Gaps = 10/158 (6%)
Frame = +2
Query: 361 IHRDLRAANILVSDTLSCKIADFGLARLIE-DNEYTAREGAKFPIKWTAPEAINYGTFTI 419
IHRDL A NILV D KI+DFGLA+ D Y PIKW +PEAI F+
Sbjct: 2 IHRDLAARNILV-DRSCVKISDFGLAQFANADGYYYGISQRDIPIKWYSPEAIETCKFSS 178
Query: 420 KSDVWSFGILLTEIVTHGRIP--YPG--MTNPEVIQNLERGYRMVRPDNCPEELY-QLMR 474
SDVWS+G+ L E+ + G IP PG +T E + L +G R+ +P+ C + +Y +LMR
Sbjct: 179 YSDVWSYGVTLFEMFSRGEIPNLLPGHDLTQEEFLNRLRKGERLPKPELCSDFVYSELMR 358
Query: 475 LCWKERPEDRPTFDYLRSVLE----DFFTATEGQYQPQ 508
CW E P+ RPTF + ++ D + G Q Q
Sbjct: 359 PCWHEMPKSRPTFHQIIQIIAREMGDNISGXAGSTQQQ 472
>17637
Length = 447
Score = 105 bits (261), Expect = 5e-23, Method: Compositional matrix adjust.
Identities = 50/132 (37%), Positives = 77/132 (58%), Gaps = 1/132 (0%)
Frame = +1
Query: 369 NILVSDTLSCKIADFGLARLIEDNEYTAR-EGAKFPIKWTAPEAINYGTFTIKSDVWSFG 427
N ++ D L K+ D L+R + +Y +G PIKW + EA+ + SDVWSFG
Sbjct: 1 NCVIDDQLRVKLTDSALSRDLFSGDYNCLGDGEYRPIKWLSLEALQKSHYNEGSDVWSFG 180
Query: 428 ILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDNCPEELYQLMRLCWKERPEDRPTF 487
+L+ E+ T G++PY + E+ L+ GYR+ +P NCP+EL+ +M CW P +RP+F
Sbjct: 181 VLMWEMCTLGKLPYAEIDPYEMEHYLKDGYRLAQPFNCPDELFTIMAYCWASMPAERPSF 360
Query: 488 DYLRSVLEDFFT 499
L+ L +F T
Sbjct: 361 SQLQICLSEFHT 396
>22005
Length = 873
Score = 83.6 bits (205), Expect(2) = 7e-23, Method: Compositional matrix adjust.
Identities = 61/194 (31%), Positives = 93/194 (47%), Gaps = 44/194 (22%)
Frame = +1
Query: 285 FLAEANLMKQLQHQRLVRLYAVVT-QEPIYIITEYMENGSLVDFLK--TPSGIKLTI--- 338
F EA+LM H +V+L V +P+ ++ E+M G L DFL+ +P L +
Sbjct: 151 FEREASLMADFDHPNIVKLLGVCAIGKPMCLLFEFMSKGDLNDFLRLCSPENYNLPVSRS 330
Query: 339 -NKLLDM------------------------------------AAQIAEGMAFIEERNYI 361
N ++D+ + QI+ GMA++ +++Y+
Sbjct: 331 QNLVVDLEDGLRVEVEAEECEKDTQSEDRDCSGMLXTKDQLYISQQISAGMAYLAQKDYV 510
Query: 362 HRDLRAANILVSDTLSCKIADFGLARLIED-NEYTAREGAKFPIKWTAPEAINYGTFTIK 420
HRDL A + S T I+DFGLAR + + Y E PI+W EAI Y F+ +
Sbjct: 511 HRDL-ATRTVXSRTT*S*ISDFGLARSVHSVDYYRGSEQDAIPIRWMPLEAILYSKFSTQ 687
Query: 421 SDVWSFGILLTEIV 434
SDVWSFG++L EI+
Sbjct: 688 SDVWSFGVVLWEIL 729
Score = 42.0 bits (97), Expect(2) = 7e-23, Method: Compositional matrix adjust.
Identities = 16/42 (38%), Positives = 28/42 (66%)
Frame = +3
Query: 440 PYPGMTNPEVIQNLERGYRMVRPDNCPEELYQLMRLCWKERP 481
PY G+T+ EV+ ++ G + +P P ++Y+LM+ CW+ RP
Sbjct: 744 PYYGLTHEEVVNYVKAGKILEQPTKTPHQVYELMKQCWQRRP 869
>08294
Length = 1849
Score = 104 bits (259), Expect = 1e-22, Method: Compositional matrix adjust.
Identities = 58/198 (29%), Positives = 100/198 (50%), Gaps = 13/198 (6%)
Frame = +2
Query: 310 EPIYIITEYMENGSLVDFL-------------KTPSGIKLTINKLLDMAAQIAEGMAFIE 356
EP ++ITEY + G L FL + P+ L +++ L M Q+A GM +
Sbjct: 926 EPHFLITEYCDWGDLKQFLLATRNDNGRGRGTRVPA---LALSQKLGMGQQVAAGMEALS 1096
Query: 357 ERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGT 416
+ +H DL A N+L++ + K+A L+ + +EY P++W PE + +
Sbjct: 1097 NQGLVHGDLAARNVLLTSRMQLKVARPALSGDVYASEYYPLHQRLVPLRWLPPEGVLEDS 1276
Query: 417 FTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDNCPEELYQLMRLC 476
T DVW+FG+ L E++ +PY M++ EV+++L+ + + P L L++ C
Sbjct: 1277 ATTCGDVWAFGVFLWEVLQLADLPYRLMSDEEVLRSLQHSQAALDSPDAPPALLSLLQRC 1456
Query: 477 WKERPEDRPTFDYLRSVL 494
++P RP F + SVL
Sbjct: 1457 TAQQPSQRPPFSEICSVL 1510
>14477
Length = 493
Score = 94.0 bits (232), Expect = 1e-19, Method: Composition-based stats.
Identities = 54/158 (34%), Positives = 87/158 (55%), Gaps = 8/158 (5%)
Frame = -1
Query: 250 RLGAGQFGEVWMGYY---NGHTKVAVKSLKQGSMSPDA---FLAEANLMKQLQHQRLVRL 303
+LGAG FG V G + VA+K LK + P + EA +MK++ H +VRL
Sbjct: 469 KLGAGNFGSVMKGVCRLDDREIPVAIKVLKNADLDPSVQSELIKEAEVMKKMDHMHIVRL 290
Query: 304 YAVVTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHR 363
+ E + ++ E + G L FL P L + +L++ Q+++GM ++E ++HR
Sbjct: 289 IGLCEGETMMLVLELAKLGPLNKFL--PKNKHLPLWNILELMWQVSQGMEYLEANKFVHR 116
Query: 364 DLRAANILVSDTLSCKIADFGLARLI--EDNEYTAREG 399
DL A NIL+ D KI+DFG+++ + E+N Y A+E
Sbjct: 115 DLAARNILLCDEHFAKISDFGMSKTLSRENNYYMAQEA 2
>01718
Length = 959
Score = 90.9 bits (224), Expect = 1e-18, Method: Compositional matrix adjust.
Identities = 70/252 (27%), Positives = 120/252 (47%), Gaps = 13/252 (5%)
Frame = +3
Query: 247 LVERLGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPDAFLAEANLMKQLQHQRLVRLYAV 306
+ E++GAG F EV+ + +V + + + L E L+ +LQH ++R V
Sbjct: 159 ICEKIGAGFFSEVFKVTHRITGQVMALKMNTMTSNRHNMLREVQLLNRLQHANILRFMGV 338
Query: 307 VTQE-PIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDL 365
E ++ +TEY+ +G+L L+ +L + + + +A G+ ++ +IHRDL
Sbjct: 339 CVHEGQLHALTEYIPSGNLEQLLEKKDE-ELPWTQRIQLTLGLARGLDYLHSTRFIHRDL 515
Query: 366 RAANILV----SDTLSCKIADFGLARLIE---DNEYTAREGAKFPIKWTAPEAINYGTFT 418
+ NIL+ + IADFGLA I D E G+ + W APE +N +
Sbjct: 516 TSKNILIRREDNHGYHAVIADFGLATKIPDPLDKEKLPTVGSPY---WMAPEVLNGHFYN 686
Query: 419 IKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLER-GYRMVRPDN----CPEELYQLM 473
++D++S GI++ EI RIP +P+++ + G V CP + QL
Sbjct: 687 ERADLFSVGIIMCEIT--ARIP----ADPDIMPRMNNFGVDYVALSEMISYCPLDYLQLA 848
Query: 474 RLCWKERPEDRP 485
C + P+ RP
Sbjct: 849 FKCCQVDPQKRP 884
>19301
Length = 712
Score = 85.9 bits (211), Expect = 4e-17, Method: Compositional matrix adjust.
Identities = 52/153 (33%), Positives = 84/153 (54%), Gaps = 1/153 (0%)
Frame = +2
Query: 235 EDEWEVPRETLKLVERLGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPDAFLAEANLMKQ 294
+D+WE+P E++ +E LG+G G V++G +VAVK ++ D + +++
Sbjct: 281 QDDWEIPFESITDLEWLGSGAQGAVFLGKLCAE-EVAVKKVR------DIKETDIRNLRK 439
Query: 295 LQHQRLVRLYAVVTQEPIY-IITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMA 353
L H ++ V TQ P Y II EY G L + L+ G ++ +LD + QIA GM
Sbjct: 440 LNHPNIISFKGVCTQAPCYCIIMEYCPYGQLYEVLR--DGKEIPPALVLDWSKQIASGMN 613
Query: 354 FIEERNYIHRDLRAANILVSDTLSCKIADFGLA 386
++ IHRDL++ N+LV+ KI+DFG +
Sbjct: 614 YLHSHKIIHRDLKSPNVLVAKNDVVKISDFGTS 712
>13305
Length = 549
Score = 84.3 bits (207), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 37/89 (41%), Positives = 52/89 (58%)
Frame = +2
Query: 399 GAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYR 458
+ PI+W A E++ T+T +SDVWSFG++L EI T G PY ++ L+ GYR
Sbjct: 2 STRVPIRWMAVESLFNNTYTTQSDVWSFGVVLWEIFTLGGTPYSSTDTQQLFAFLKDGYR 181
Query: 459 MVRPDNCPEELYQLMRLCWKERPEDRPTF 487
+ RP C + Y +M CW E + RPTF
Sbjct: 182 LKRPKLCDQNTYAMMLQCWNENAQRRPTF 268
>13592
Length = 980
Score = 77.8 bits (190), Expect = 9e-15, Method: Compositional matrix adjust.
Identities = 60/252 (23%), Positives = 123/252 (48%), Gaps = 17/252 (6%)
Frame = +2
Query: 250 RLGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPDAFLAEANLMKQLQ------HQRLVRL 303
++G G+FG+V+ N ++ ++K+ ++ P A N+ ++L+ H+ LVR
Sbjct: 5 KIGQGRFGKVYTAVNNNTGELM--AMKEIAIQPGETRALKNVAEELKILEGIKHKNLVRY 178
Query: 304 YAV-VTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIH 362
Y + V +E + I E G+L ++ G+ +++ AQ+ G+A + + +H
Sbjct: 179 YGIEVHREELLIFMELCSEGTLESLVELTGGLPEALSR--RFTAQLLSGVAELHKHGIVH 352
Query: 363 RDLRAANI-LVSDTLSCKIADFGLARLIEDNE--------YTAREGAKFPIKWTAPEAIN 413
RD++ ANI LV + S K+ DFG A I+ + Y + P +T +
Sbjct: 353 RDIKTANIFLVDGSNSLKLGDFGSAVKIQAHTTVPGELQGYVGTQAYMAPEVFTKTNSDG 532
Query: 414 YGTFTIKSDVWSFGILLTEIVTHGRIPYPGM-TNPEVIQNLERGYRMVRPDNCPEELYQL 472
+G +D+WS G ++ E+ + G+ P+ +N +++ + G + P++ +E +
Sbjct: 533 HGRL---ADIWSVGCVVVEMAS-GKRPWAQFDSNFQIMFKVGMGEKPQAPESLSQEGHDF 700
Query: 473 MRLCWKERPEDR 484
+ C + P+ R
Sbjct: 701 IDHCLQHDPKQR 736
>18921
Length = 697
Score = 77.4 bits (189), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 51/196 (26%), Positives = 96/196 (48%), Gaps = 3/196 (1%)
Frame = +2
Query: 241 PRETLKLVERLGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPDA--FLAEANLMKQLQHQ 298
P + ++ +LG G +G V+ + +V ++KQ + D + E ++M+Q +
Sbjct: 23 PEDVFDILGKLGEGSYGSVFKSLHKETGQVL--AIKQVPVDTDLQEIIKEISIMQQCDSK 196
Query: 299 RLVRLY-AVVTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEE 357
+V+ Y + ++I+ EY GS+ D ++ + L ++ + +G+ ++
Sbjct: 197 YIVKYYGSYFKNTDLWIVMEYCGAGSVSDIMRLRNK-TLVEREIATILYYTLKGLXYLHS 373
Query: 358 RNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTF 417
R IHRD++A NIL+++ K+ADFG+A + D P W APE I +
Sbjct: 374 RRKIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTPY-WMAPEVIQEIGY 550
Query: 418 TIKSDVWSFGILLTEI 433
+D+WS GI E+
Sbjct: 551 DCVADIWSLGITALEM 598
>12721
Length = 821
Score = 77.4 bits (189), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 46/196 (23%), Positives = 94/196 (47%), Gaps = 2/196 (1%)
Frame = +1
Query: 241 PRETLKLVERLGAGQFGEVWMGYYNGHTKVAVKSLK-QGSMSPDAFLAEANLMKQLQHQR 299
PR L ++G G G V + ++AVK + + + E +M+ H
Sbjct: 82 PRTFLDDFMKIGEGSTGIVCIATSRDGRQMAVKKMDLRKQQRRELLFNEVVVMRDYHHPN 261
Query: 300 LVRLY-AVVTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEER 358
+V +Y + + + ++++ E+ME G+L D + + ++ ++ + + +AF+
Sbjct: 262 IVEMYNSYLVNDELWVVMEFMEGGALTDIV---TNNRMDEVQIATVCRACLKALAFLHAN 432
Query: 359 NYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFT 418
IHRD+++ +IL+S K+ DFG + + + P W APE I+ +
Sbjct: 433 GVIHRDIKSDSILLSHDGKVKLXDFGFCAQVTQDLQKRKSLVGTPY-WMAPEVISRLPYG 609
Query: 419 IKSDVWSFGILLTEIV 434
+ D+WS GI++ E++
Sbjct: 610 PEVDIWSLGIMVMEMI 657
>07833
Length = 1504
Score = 77.0 bits (188), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 60/220 (27%), Positives = 108/220 (49%), Gaps = 9/220 (4%)
Frame = -3
Query: 285 FLAEANLMKQLQHQRLVRLYAVVTQEP-IYIITEYMENGSLVDFLKTPSGIKLTINKLLD 343
F+ E ++ H ++ + A Q P + +I+++M GSL + L SGI + N+ L
Sbjct: 1478 FMEEFPRLRIFNHPNVLPVLACCNQPPNLVLISQFMPFGSLYNTLHGESGIVVDQNQSLR 1299
Query: 344 MAAQIAEGMAFIE--ERNYIHRDLRAANILVSDTLSCKI--ADFGLARLIEDNEYTAREG 399
A IA GM F+ E + L + ++++ + L+ +I AD+ + +G
Sbjct: 1298 FAMDIARGMEFLHSMEPTIPNFLLTSKHVMIDEDLTARINMADYCFS--------FHEKG 1143
Query: 400 AKFPIKWTAPEAINY---GTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEV-IQNLER 455
+ W APEA+ T +D+WSF IL+ E+ T +P+ +++ EV ++
Sbjct: 1142 KVYSPAWMAPEALQRRPDDINTRAADMWSFAILMWELETR-EVPFAELSSMEVGMKVALE 966
Query: 456 GYRMVRPDNCPEELYQLMRLCWKERPEDRPTFDYLRSVLE 495
G R+ P + +L+++C E P RP FD + +LE
Sbjct: 965 GLRISIPPGISLHMSRLIKICMNEEPGKRPRFDMIIPILE 846
>01060
Length = 1800
Score = 76.3 bits (186), Expect = 3e-14, Method: Compositional matrix adjust.
Identities = 58/230 (25%), Positives = 112/230 (48%), Gaps = 6/230 (2%)
Frame = +1
Query: 237 EWEVPRETLKLVERLGAGQFGEVWMGYYNGH-TKVAVKSLK-QGSMS--PDAFLAEANLM 292
++E L +++G G +G V+ + K+A+K ++ +GS P + + E ++
Sbjct: 55 DFETALSDLTDFQKIGEGTYGVVYKCRHRATGRKLAMKKIRLRGSEDGVPSSAIREIAML 234
Query: 293 KQLQHQRLVRLYAVVTQ-EPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEG 351
++L+H +V L V+ + E ++++ E++ + K P G+ L + QI G
Sbjct: 235 RELRHTNIVCLEDVIMEDERLFLVFEFLSMDLKMYIDKFPEGVVLDRRLVKSYVFQIVTG 414
Query: 352 MAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEA 411
+ F +R +HRDL+ N+L++ T + KIADFG+AR A + + APE
Sbjct: 415 IXFCHQRRIVHRDLKPQNLLINHTGAIKIADFGMARTFA-LPVRAYTHEVVTLWYRAPEI 591
Query: 412 I-NYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMV 460
+ ++ DVWS G + +++ I P I L + +R++
Sbjct: 592 LMGASKYSTPVDVWSIGTIFADML----IRTPIFKGDSEIDQLFKIFRII 729
>29581
Length = 1278
Score = 75.1 bits (183), Expect = 6e-14, Method: Compositional matrix adjust.
Identities = 53/187 (28%), Positives = 98/187 (52%), Gaps = 10/187 (5%)
Frame = -2
Query: 275 LKQGSMSPDAFLAEANLMKQLQHQRLVRLYAVV---TQEPIYIITEYMEN--GSLVDFLK 329
L++ +SP + + L+HQ +V+L VV + + ++++ EY E SL+D +
Sbjct: 1244 LERDMVSPSVVCVRSTFLLNLRHQNIVQLQEVVVGKSLDSLFLVMEYCEQDLASLLDNMP 1065
Query: 330 TPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLI 389
P + +++ + Q+ +G+ ++ E IHRDL+ +N+L++D KIADFGLAR
Sbjct: 1064 AP----FSESQVKCIVLQLLKGLRYLHEAFIIHRDLKVSNLLMTDKGCVKIADFGLAR-- 903
Query: 390 EDNEYTAREGAKFP----IKWTAPEAI-NYGTFTIKSDVWSFGILLTEIVTHGRIPYPGM 444
Y + P + + APE + T + D+WS G +L E++ H + PG
Sbjct: 902 ---NYGKPQKPMTPKVVTLWYRAPELLFGSKTHSTAIDMWSAGCILGELLGHKPL-MPGR 735
Query: 445 TNPEVIQ 451
++ + I+
Sbjct: 734 SDLQQIE 714
>17253
Length = 483
Score = 72.8 bits (177), Expect = 3e-13, Method: Composition-based stats.
Identities = 45/153 (29%), Positives = 75/153 (49%), Gaps = 16/153 (10%)
Frame = -1
Query: 270 VAVKSLKQGSMSPDA--FLAEANLMKQL-QHQRLVRLYAVVT-QEPIYIITEYMENGSLV 325
VAVK+ + + + FL E ++M++L +H +V T +P I+ E+ +G L+
Sbjct: 459 VAVKTHNEAATDAEKSEFLRELSIMRKLPRHPNVVSFMGCCTMSDPALILMEFCCHGDLL 280
Query: 326 DFLK----------TPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDT 375
FL+ T + LT A +A GMA + +HRD+ A N+L+S+
Sbjct: 279 SFLRKRRPDRTVFLTSTANDLTARDFFSFALHVARGMAHVANNKIVHRDVAARNVLISER 100
Query: 376 LSCKIADFGLARLIEDNE--YTAREGAKFPIKW 406
CK++DFGL+R + D Y P++W
Sbjct: 99 NVCKVSDFGLSRRVGDQNDVYEIVSRRPLPLRW 1
>14126
Length = 1265
Score = 72.4 bits (176), Expect = 4e-13, Method: Compositional matrix adjust.
Identities = 56/202 (27%), Positives = 97/202 (48%), Gaps = 14/202 (6%)
Frame = +3
Query: 248 VERLGAGQFGEVWMG--YYNGHTKVAVKSLKQGSMS---PDAFLAEANLMKQLQ---HQR 299
V +G G +G V+ N VA+K ++ + P + E +++KQL+ H
Sbjct: 204 VAVIGNGAYGTVYKARDLRNQGEFVAMKRIRLNNTEEGMPMMAIREISMLKQLEQYEHPN 383
Query: 300 LVRLYAV----VTQEPIYI--ITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMA 353
+VRL V +T I + + EY+E+ K PS L +++ D+ Q+ G+
Sbjct: 384 VVRLLDVSHNTITDREIRLNLVFEYIEHDLATYLAKCPSP-GLGPDRIKDLMLQLLNGVD 560
Query: 354 FIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAIN 413
F+ +HRDL+ N+L+S K+ADFGLAR+ + + A + + +PE +
Sbjct: 561 FLHSNRIVHRDLKPQNLLISKDGRLKLADFGLARIY--SFHMALTTVVVTLWYRSPEVLM 734
Query: 414 YGTFTIKSDVWSFGILLTEIVT 435
+ D+WS G + E+ T
Sbjct: 735 QAEYGTSVDIWSCGCIFAELFT 800
>01707
Length = 757
Score = 72.0 bits (175), Expect = 6e-13, Method: Compositional matrix adjust.
Identities = 56/212 (26%), Positives = 108/212 (50%), Gaps = 8/212 (3%)
Frame = +1
Query: 243 ETLKLVERLGAGQFGEVWMGYYNGHTK-VAVKSLKQGSMSP---DAFLAEANLMKQLQHQ 298
E + + ++G G +G V+ ++ VA+K + P + E ++KQL+H
Sbjct: 64 EKYEKIGKIGEGSYGVVFKCRNKETSQLVAIKKFVESEDDPLIKKIAMREIRMLKQLKHP 243
Query: 299 RLVRLYAVVTQEP-IYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEE 357
LVRL V ++ ++++ +Y+++ L + + P G+ + K + Q + F +
Sbjct: 244 NLVRLIEVFRRKKRLHLVFDYVDHTLLNELDRYPRGLPEPMVK--RIIYQTLLAVNFCHQ 417
Query: 358 RNYIHRDLRAANILVSDTLSCKIADFGLARLIE--DNEYTAREGAKFPIKWTAPEAINYG 415
N IHRD++ NIL++ K+ DFG AR++ +EYT ++ + APE +
Sbjct: 418 YNTIHRDVKPENILITRQGQVKLCDFGFARILTGPGDEYTDYVATRW---YRAPELLVGD 588
Query: 416 T-FTIKSDVWSFGILLTEIVTHGRIPYPGMTN 446
T + DVW+ G + E++T G+ +PG ++
Sbjct: 589 TQYGPPVDVWAIGCVFAELLT-GQALWPGRSD 681
>01756
Length = 1858
Score = 68.6 bits (166), Expect = 6e-12, Method: Compositional matrix adjust.
Identities = 61/232 (26%), Positives = 102/232 (43%), Gaps = 33/232 (14%)
Frame = -3
Query: 241 PRETLKL-----------VERLGAGQFGEVWMGYYN------GHTKVAVKSLKQGSMSPD 283
P ETLK + ++G G FGEV+ KV + + K+G P
Sbjct: 1781 PYETLKFPFCDEDAKYEKLAKIGQGTFGEVFKARCKKTKQVVAMKKVLMDNEKEGF--PI 1608
Query: 284 AFLAEANLMKQLQHQRLVRLYAVVTQEP---------IYIITEYMENGSLVDFLKTPSGI 334
L E +++ L H+ +V L + + + Y++ E+ E+ L L S +
Sbjct: 1607 TALREIKILQLLNHENVVDLIEICSTKATSANRYKSMFYLVFEFCEH-DLAGLLSNMSVV 1431
Query: 335 KLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLAR-----LI 389
+ ++ ++ Q+ G+ +I +HRD++AANIL++ K+ADFGLAR L
Sbjct: 1430 -FNLPEIKEVMKQLMNGLYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLR 1254
Query: 390 EDNEYTAREGAKFPIKWTAPEAINYG--TFTIKSDVWSFGILLTEIVTHGRI 439
+ N YT R W P + G ++ D W G ++ E+ T I
Sbjct: 1253 QPNRYTNR----VVTLWYRPPELLLGDRNYSTAIDQWGAGCIMAEMWTRNPI 1110
>00300
Length = 2318
Score = 68.2 bits (165), Expect = 8e-12, Method: Compositional matrix adjust.
Identities = 59/263 (22%), Positives = 117/263 (44%), Gaps = 13/263 (4%)
Frame = -1
Query: 250 RLGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPD------AFLAEANLMKQLQHQRLVRL 303
++G GQFG+V+ + + +LK+ P+ E + + +QH+ LV+
Sbjct: 1637 KIGEGQFGKVYTAV--NMSTGELMALKEMKFQPNDLQQLREMCDEIKIFEGIQHENLVKY 1464
Query: 304 YAV-VTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIH 362
Y V V ++ + + EY + G++ + K + L + +I + + E + +H
Sbjct: 1463 YGVEVHKDEMLMFMEYCDTGTIEEAAK----MGLPEYLIRRYTREIVLAVNHLHENSIVH 1296
Query: 363 RDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKF--PIKWTAPEAI---NYGTF 417
RD++ ANI ++ K+ DFG + ++ + E + APE + G +
Sbjct: 1295 RDIKGANIFLTSNGHVKLGDFGCSVKLKSHTTMPGEFHNLVGTTAYMAPEVFTQNDQGGY 1116
Query: 418 TIKSDVWSFGILLTEIVTHGRIPYPGMTNP-EVIQNLERGYRMVRPDNCPEELYQLMRLC 476
+D+WS G ++ E+ T G+ P+ + N +++ + G++ PD+ E + L
Sbjct: 1115 GRAADIWSLGCVVIEMAT-GKRPWHDLDNNYQIMYKVGIGHKPAVPDSLSVEGKHFLDLI 939
Query: 477 WKERPEDRPTFDYLRSVLEDFFT 499
P R L L+ FT
Sbjct: 938 MCHDPAQRALASQL---LDHTFT 879
>00715
Length = 1788
Score = 67.0 bits (162), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 49/172 (28%), Positives = 82/172 (47%), Gaps = 27/172 (15%)
Frame = +1
Query: 342 LDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLI------------ 389
L +A Q+A G+ ++ N +H DL+ AN L++ L +IADFG +
Sbjct: 247 LSLALQMARGLHYLHSINIVHLDLKPANCLLTRDLKLRIADFGCCHQLTPTGLDMGEREG 426
Query: 390 ----EDNEYTAREGA-----KFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIP 440
+ E T +GA + + APE + +++SDV+S GI L ++ T + P
Sbjct: 427 GMAGNELELTPVQGAWKNELAGTLAYRAPELLKGLQPSVRSDVYSLGITLWQMCTR-QGP 603
Query: 441 YPGMTNPEVI-QNLERGYRMVRPDNCPEELYQLM-----RLCWKERPEDRPT 486
Y G+ V+ Q + + R P + ++ +++M CW R EDRPT
Sbjct: 604 YEGVPAHAVVYQVVSKDLRPCPPPSTEDDPFEVMFRDLYTQCWARRVEDRPT 759
>01966
Length = 1735
Score = 65.1 bits (157), Expect = 6e-11, Method: Compositional matrix adjust.
Identities = 38/123 (30%), Positives = 71/123 (57%), Gaps = 4/123 (3%)
Frame = -1
Query: 269 KVAVKSLK-QGSMS--PDAFLAEANLMKQLQHQRLVRLYAVVTQ-EPIYIITEYMENGSL 324
K+A+K ++ +GS P + + E ++++L+H +V L V+ + E ++++ E++
Sbjct: 1630 KLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTNIVCLEDVIMEDERLFLVFEFLSMDLK 1451
Query: 325 VDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFG 384
+ K P G+ L + QI G+ F +R +HRDL+ N+L++ T + KIADFG
Sbjct: 1450 MYIDKFPEGVVLDRRLVKSYVFQIVTGINFCHQRRIVHRDLKPQNLLINHTGAIKIADFG 1271
Query: 385 LAR 387
+AR
Sbjct: 1270 MAR 1262
>14420
Length = 528
Score = 64.7 bits (156), Expect = 9e-11, Method: Compositional matrix adjust.
Identities = 39/162 (24%), Positives = 80/162 (49%), Gaps = 3/162 (1%)
Frame = +2
Query: 283 DAFLAEANLMKQLQHQRLVR-LYAVVTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKL 341
+ + E +M++ Q+ +V L + + E ++++ E++ GSL D + + ++
Sbjct: 35 ELIINEILVMRENQNPNIVNYLDSYLVGEELWVVMEFLAGGSLTDVVTETC---MDEGQI 205
Query: 342 LDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLI--EDNEYTAREG 399
+ + + + F+ E IHRD+++ NIL+ S K+ DFG + E ++ + G
Sbjct: 206 AAVCRECLQALEFLHENQVIHRDIKSDNILLGMDGSVKLTDFGFCAQLSPEQSKRSTMVG 385
Query: 400 AKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPY 441
+ W APE + + D+WS G++ E++ G PY
Sbjct: 386 TPY---WMAPEVVTRKQYGPTVDIWSLGVMCIEMI-EGEPPY 499
>27546
Length = 426
Score = 63.9 bits (154), Expect = 1e-10, Method: Composition-based stats.
Identities = 33/108 (30%), Positives = 59/108 (54%), Gaps = 1/108 (0%)
Frame = -1
Query: 285 FLAEANLMKQLQHQRLVRLYAVVTQEP-IYIITEYMENGSLVDFLKTPSGIKLTINKLLD 343
F E ++ +L H ++++++++ + P I+I Y E G ++ +K I K+
Sbjct: 339 FPRELEILTRLDHPNIIQIHSILQRGPKIFIFMRYAEKGDMLSHIKKTGPIDEAQTKVWF 160
Query: 344 MAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIED 391
Q+A+ + ++ + HRDL+ NIL+S L+ KIADFG AR D
Sbjct: 159 F--QMAKALQYLHSHDIAHRDLKCENILLSKRLNVKIADFGFARYCRD 22
>18484
Length = 635
Score = 63.2 bits (152), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 39/140 (27%), Positives = 70/140 (50%)
Frame = +1
Query: 345 AAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPI 404
AA+IA G+ F+ ++ I+RDL+ N+++ KIADFG+ + + T R P
Sbjct: 61 AAEIAVGLFFLHDQGIIYRDLKLDNVMLDSEGHIKIADFGMCKEGMTGDATTRTFCGTP- 237
Query: 405 KWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDN 464
+ APE + Y ++ D W++G+LL E++ G+ P+ G E+ ++ + + P
Sbjct: 238 DYIAPEIVLYQPYSKSVDWWAYGVLLFEMLA-GQPPFDGEDEDELFSSI-TDHNVSYPKA 411
Query: 465 CPEELYQLMRLCWKERPEDR 484
E L + + P R
Sbjct: 412 MSREAVSLCKGLLMKNPTKR 471
>12672
Length = 773
Score = 63.2 bits (152), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 43/166 (25%), Positives = 72/166 (43%), Gaps = 17/166 (10%)
Frame = +3
Query: 349 AEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPI---K 405
A G+ ++ + ++HRD++ ANIL+ + K+ DF E + A I
Sbjct: 21 ASGIQYLNDNGHVHRDIKTANILLDSEYTAKVGDFATVVSAPSGEGKTVQNASVVIGTAA 200
Query: 406 WTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIP--------------YPGMTNPEVIQ 451
+ APEAI++ T K D +SFG++L E++T G + + PE I
Sbjct: 201 YLAPEAIHFDVST-KLDSYSFGVVLLEVIT-GLVAQDYSREERTLSSHIMENVEEPEEIH 374
Query: 452 NLERGYRMVRPDNCPEELYQLMRLCWKERPEDRPTFDYLRSVLEDF 497
+ PD ++LY + C + RP +R LE+
Sbjct: 375 DFVDQSAGTWPDGAVDKLYDISMRCLNLSKKQRPNVKDIRPELEEL 512
>25550
Length = 941
Score = 60.5 bits (145), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 28/63 (44%), Positives = 39/63 (61%)
Frame = +3
Query: 439 IPYPGMTNPEVIQNLERGYRMVRPDNCPEELYQLMRLCWKERPEDRPTFDYLRSVLEDFF 498
+ YPG+ EV LERGYRM RP P ++Y LM CW+ P++RPTF + +LE+ F
Sbjct: 36 VXYPGVDLTEVYHLLERGYRMERPQGTPADVYILMLKCWQWDPKERPTFKEIHYLLENMF 215
Query: 499 TAT 501
+
Sbjct: 216 EKS 224
>04591
Length = 1117
Score = 60.5 bits (145), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 42/166 (25%), Positives = 82/166 (49%), Gaps = 14/166 (8%)
Frame = -2
Query: 282 PDAFLAEANLMKQLQHQRLVRLYAVVTQEP---------IYIITEYMEN--GSLVDFLKT 330
P L E +++QL+H+ +V+L + + Y+I EY + L++ L+
Sbjct: 1089 PITALREIKILQQLEHENVVQLQEICHTQAGPYNRYKSTFYLIFEYCDYDLAGLLNNLR- 913
Query: 331 PSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLAR-LI 389
+K ++ ++ +Q+ G+ +I + +HRD++AANIL++ K+ADFGL+R +
Sbjct: 912 ---VKFSLADKKNLMSQLLNGLFYIHTKQILHRDIKAANILLTRDGVLKLADFGLSRPWV 742
Query: 390 EDNEYTAREGAKFPIKWTAPEAINYG--TFTIKSDVWSFGILLTEI 433
+ T R W P + G + + D+W G ++ E+
Sbjct: 741 KSKRLTNR----VVTLWYRPPELLLGEREYGPEIDMWGVGCIMAEM 616
>07836
Length = 1478
Score = 59.3 bits (142), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 61/220 (27%), Positives = 105/220 (47%), Gaps = 45/220 (20%)
Frame = -1
Query: 312 IYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNY--------IHR 363
+++IT+Y ENGSL D+L + L +++L +A G+A + + HR
Sbjct: 1328 LFLITDYHENGSLHDYLLSRV---LDSSEMLALAHSAICGLAHLHIEIFGTRGKPAIAHR 1158
Query: 364 DLRAANILVSDTLSCKIADFGLA-RLI-EDNEYTA----REGAKFPIKWTAPEAI----- 412
D+++ NILV +C IAD GLA R I E NE R+G K ++ APE +
Sbjct: 1157 DIKSKNILVKKNGTCCIADLGLAVRYISESNEVDVAPNPRQGTK---RYMAPEVLEMLLN 987
Query: 413 --NYGTFTIKSDVWSFGILLTEI----VTHG-----RIPY-------PGMTNPEVIQNLE 454
N+ F ++D+++FG+++ EI V G ++P+ P + ++ +++
Sbjct: 986 VKNFDAFK-QADMYAFGLVMWEIARCCVIGGVAEEYQVPFYNCLPHDPSFEDVRLVVSVD 810
Query: 455 RGYRMVRPDN--------CPEELYQLMRLCWKERPEDRPT 486
+ VRPD + + ++M CW P R T
Sbjct: 809 K----VRPDIPLRWQEDPIMKVMVKVMCECWSGNPAARLT 702
>31885
Length = 529
Score = 57.0 bits (136), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 41/169 (24%), Positives = 76/169 (44%), Gaps = 8/169 (4%)
Frame = -2
Query: 289 ANLMKQLQHQRLVRL-YAVVTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQ 347
+++ +L H LV L YA +E ++++ + G L ++ + K Q
Sbjct: 519 VDMLTRLDHPFLVNLWYAFQDEEDLFMVVDLFLGGDLRYHMQQEVSFREDCVKF--YLCQ 346
Query: 348 IAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWT 407
+A + ++ + +HRD++ NIL+ + C + DF +A +ED+E P +
Sbjct: 345 LALVLDYLRSQKIVHRDIKPDNILLDEQGHCHVTDFNIATQLEDDELATSTSGTRP--YM 172
Query: 408 APEAINYGT-------FTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEV 449
APE YG + D WS G+ L E++ R P+ +N +
Sbjct: 171 APEV--YGVAINERRGYGFPVDWWSLGVSLFELLKKRR-PFSVHSNTSL 34
>17975
Length = 449
Score = 56.6 bits (135), Expect = 3e-08, Method: Composition-based stats.
Identities = 38/124 (30%), Positives = 65/124 (52%), Gaps = 6/124 (4%)
Frame = +3
Query: 269 KVAVKSL---KQGSMSPDAFLAEANLMKQLQHQRLVRLYAVV-TQEPIYIITEYMENGSL 324
KVAVK + K +S E MK +QH +VRLY V+ TQ +Y+I E + G +
Sbjct: 48 KVAVKVIDKTKLDEVSRSHLFQEVRCMKLVQHPNVVRLYEVIDTQTKLYLILELGDGGDM 227
Query: 325 VDF-LKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLS-CKIAD 382
D+ ++ G++ + K QI E +++ + + +HRDL+ N++ + K+ D
Sbjct: 228 YDYIMRHSGGLEEKLAK--RYFRQIVEAISYCHKLHVVHRDLKPENVVFFEKPGLVKLTD 401
Query: 383 FGLA 386
FG +
Sbjct: 402 FGFS 413
>13066
Length = 551
Score = 56.2 bits (134), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 42/172 (24%), Positives = 80/172 (46%), Gaps = 8/172 (4%)
Frame = +3
Query: 264 YNGHTKVAVKSLKQGSMSPDA----FLAEANLMKQLQHQRLVRLYAVVTQEPI-YIITEY 318
Y + K+A K + + D F E +L+ +L H ++++++++ + P +I +
Sbjct: 42 YGRNIKLACKIIDKEKAPVDFVEKFFPRELDLLTKLDHPYIIQIHSILQRXPKNFIFMRF 221
Query: 319 MENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSC 378
E G L+ +++ +K K+ Q+ + ++ + HRDL+ NIL+S +
Sbjct: 222 AERGDLLTYIQEVGFVKEKQAKI--WFYQMTTALNYLHSYDVAHRDLKCENILLSSHFNV 395
Query: 379 KIADFGL--ARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIK-SDVWSFG 427
K+ADFG A + E E + APE + + K +D WS G
Sbjct: 396 KLADFGFACACITESGEKYMSRTYCGSAAYAAPEIVYGAPYAPKVADAWSLG 551
>19094
Length = 898
Score = 55.1 bits (131), Expect = 7e-08, Method: Compositional matrix adjust.
Identities = 29/84 (34%), Positives = 45/84 (53%)
Frame = +1
Query: 350 EGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAP 409
+G+ ++ R IHRD++A NIL+++ K+ADFG+A + D P W AP
Sbjct: 91 KGL*YLHSRRKIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTP-YWMAP 267
Query: 410 EAINYGTFTIKSDVWSFGILLTEI 433
E I + +D+WS GI E+
Sbjct: 268 EVIQEIGYDCVADIWSLGITALEM 339
>09606
Length = 1300
Score = 54.7 bits (130), Expect = 9e-08, Method: Compositional matrix adjust.
Identities = 49/225 (21%), Positives = 88/225 (39%), Gaps = 22/225 (9%)
Frame = -3
Query: 243 ETLKLVERLGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPDAFLAEANLMKQLQHQRLVR 302
E L E LG G+ ++ G G + P+ + + H +V+
Sbjct: 1115 ENFVLYEELGKGEHSIIYKGRRKGTINFVAIHCIEKCKRPEV-TNTVRMTHDISHPNVVQ 939
Query: 303 LYA-VVTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYI 361
+ T ++++ E GSL D L + T + D + G+ +I +
Sbjct: 938 FHEWYETSNHLWLVVELCTGGSLADILAQDHHLPET--SIRDFGIHLVTGLHYIHSLGIL 765
Query: 362 HRDLRAANILVSDTLSCKIADFGLARLIEDNEYT-----AREGAKFPIK----------- 405
DLR + +L+ + K ADFGL+++ +N A G ++ I+
Sbjct: 764 FHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQWNIQSAEEMMKQVPT 585
Query: 406 -----WTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMT 445
+ APE +I SD+W+ G + E+ + G P+ G T
Sbjct: 584 SGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFS-GHPPFLGET 453
>03240
Length = 1683
Score = 53.9 bits (128), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 63/284 (22%), Positives = 120/284 (42%), Gaps = 55/284 (19%)
Frame = -3
Query: 248 VERLGAGQFGEVWMGYYNGHTKV-AVKSLKQGSM----SPDAFLAEANLMKQLQHQRLVR 302
++ LG G FGEV + N + A+K+L++ + AE +++ + ++ +V+
Sbjct: 1276 IKTLGVGAFGEVSLCRKNDTGMLYAMKTLRKSDVLKRNQVAHVKAERDILAEADNEWVVK 1097
Query: 303 LY-AVVTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYI 361
LY + +Y + +Y+ G L+ L + + + A++ + + + +I
Sbjct: 1096 LYYSFQDHNYLYFVMDYVPGGDLMGLLIRMEILDEPLARFY--VAELVQAIESVHRMGFI 923
Query: 362 HRDLRAANILVSDTLSCKIADFGLA---RLIEDNEYTAREGAKF---------------- 402
HRD++ NIL+ K+ DFGL R +++Y R+G
Sbjct: 922 HRDIKPDNILIDRNGHIKLTDFGLCTGFRWTHNSKYYQRDGTHARQDSMEVKCQLDEQCQ 743
Query: 403 -----PIK-------------------WTAPEAIN-YGTFTIKSDVWSFGILLTEIVTHG 437
P++ + APE ++ G +T D WS G++L E++ G
Sbjct: 742 CEILKPLERRRKREQRCLAHSLVGTPNYIAPEVLSRLGGYTSVCDWWSVGVILFEMLV-G 566
Query: 438 RIPY----PGMTNPEVIQNLERGYRMVRPDNCPEELYQL-MRLC 476
P+ P T +VI N + ++ R N + L +RLC
Sbjct: 565 HPPFYANTPAETQYKVI-NWKDMLKIPRESNLSQPAKDLILRLC 437
>21079
Length = 878
Score = 50.8 bits (120), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 38/137 (27%), Positives = 68/137 (49%), Gaps = 4/137 (2%)
Frame = +1
Query: 297 HQRLVRLY-AVVTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFI 355
H +L+ L+ A + ++ E++ G L + + + LT + QI G+ ++
Sbjct: 1 HPKLLMLWDAFEAPRTMVLVMEFVGAGELFERVIRDDFV-LTERDCVHFVRQICSGVGYM 177
Query: 356 EERNYIHRDLRAANIL-VSDTLS-CKIADFGLARLIE-DNEYTAREGAKFPIKWTAPEAI 412
++ +H DL+ N+L VSD + KI DFGLAR + + G ++ APE +
Sbjct: 178 HTQSILHLDLKPENVLCVSDNSNQIKIIDFGLARFYKPGDSLQVLFGTP---EFIAPEVV 348
Query: 413 NYGTFTIKSDVWSFGIL 429
NY +D+WS G++
Sbjct: 349 NYDEINFTTDMWSIGVI 399
>30755
Length = 1137
Score = 50.8 bits (120), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 37/142 (26%), Positives = 69/142 (48%), Gaps = 2/142 (1%)
Frame = +2
Query: 345 AAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEY--TAREGAKF 402
A+I + ++ + I+RDL+ N+L+ K+ADFGL + ED Y T +
Sbjct: 50 GAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCK--EDITYGRTTKTFCGT 223
Query: 403 PIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRP 462
P ++ APE ++ + D W G+++ E++ GR+P+ + +V+ L + P
Sbjct: 224 P-EYLAPEVLDDNDYGRAVDWWGTGVVMYEMIC-GRLPFYNRDH-DVLFTLILVEDVKFP 394
Query: 463 DNCPEELYQLMRLCWKERPEDR 484
N +E L+ + P +R
Sbjct: 395 RNITDEAKSLLSGLLAKDPRNR 460
>15910
Length = 1361
Score = 49.7 bits (117), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 34/114 (29%), Positives = 57/114 (50%), Gaps = 3/114 (2%)
Frame = +2
Query: 346 AQIAEGMAFIEERNYIHRDLRAANIL---VSDTLSCKIADFGLARLIEDNEYTAREGAKF 402
+ I G+ +I +HRDL+ N+L ++D K+ADFGL+R+IE E
Sbjct: 485 SDILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLADFGLSRIIEP-EVQMSTVCGT 661
Query: 403 PIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERG 456
P + APE + +T D+WS G+ + I+ G P+ E+ + + +G
Sbjct: 662 P-GYCAPEVLKGDKYTPSVDMWSVGV-IAYILLCGYEPFFAENEFEMYRKIIKG 817
>04138
Length = 800
Score = 49.3 bits (116), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 32/97 (32%), Positives = 47/97 (48%), Gaps = 7/97 (7%)
Frame = +1
Query: 350 EGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLAR-----LIEDNEYTAREGAKFPI 404
E + +I +HRD++AANIL++ K+ADFGLAR L + N YT R
Sbjct: 46 ERLYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNR----VVT 213
Query: 405 KWTAPEAINYG--TFTIKSDVWSFGILLTEIVTHGRI 439
W P + G ++ D W G ++ E+ T I
Sbjct: 214 LWYRPPELLLGDRNYSTAIDQWGAGCIMAEMWTRNPI 324
>13212
Length = 1067
Score = 49.3 bits (116), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 28/93 (30%), Positives = 48/93 (51%), Gaps = 7/93 (7%)
Frame = -1
Query: 347 QIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKF--PI 404
++ + F+ + IHRD++A N+L++ K+ADFG++ N T ++ F
Sbjct: 956 EMCMALDFLHRHHVIHRDIKAGNVLLTIDGEVKLADFGVSA---KNTQTQQKRDTFIGTP 786
Query: 405 KWTAPEAINYGT-----FTIKSDVWSFGILLTE 432
W APE + T + K+D+WS G+ L E
Sbjct: 785 YWMAPEVVLCETLKDTPYDFKADIWSLGVTLIE 687
>26711
Length = 405
Score = 47.4 bits (111), Expect = 2e-05, Method: Composition-based stats.
Identities = 33/111 (29%), Positives = 58/111 (52%), Gaps = 3/111 (2%)
Frame = -2
Query: 347 QIAEGMAFIEERNYIHRDLRAANILVS-DTL-SCKIADFGLAR-LIEDNEYTAREGAKFP 403
Q+ + + + + +H DL+ +N+L+S D L S ++ DFGLAR L E G
Sbjct: 392 QVLDILQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARKLYPPQETFLNHGTP-- 219
Query: 404 IKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLE 454
+T+PEA++ + SDVW G+ L I+ G+ P+ + E ++ +
Sbjct: 218 -GFTSPEALDVKPISTASDVWGVGV-LAYILLSGQSPFQADSATESLKKTQ 72
>35671
Length = 567
Score = 46.6 bits (109), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 18/47 (38%), Positives = 31/47 (65%)
Frame = -3
Query: 454 ERGYRMVRPDNCPEELYQLMRLCWKERPEDRPTFDYLRSVLEDFFTA 500
++G R+ +P +C +E Y++M CW E E+RPTF L V+E+ + +
Sbjct: 565 QKGNRLAKPISCTDEAYKVMLQCWTESREERPTFKKLVPVMENLYRS 425
>01392
Length = 1806
Score = 45.4 bits (106), Expect = 5e-05, Method: Compositional matrix adjust.
Identities = 34/109 (31%), Positives = 53/109 (48%), Gaps = 12/109 (11%)
Frame = -1
Query: 347 QIAEGMAFIEERNYIHRDLRAANIL---VSDTLSCKIADFGLARLIE-DNEYTAREGAKF 402
IA + F+ + HRDL+ NIL + D + KI DF LA I D + T
Sbjct: 1767 HIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGISCDGDGTKTPELLT 1588
Query: 403 PI---KWTAPEAINY-----GTFTIKSDVWSFGILLTEIVTHGRIPYPG 443
P+ ++ APE ++ ++ + D+WS GI+L I+ G P+ G
Sbjct: 1587 PVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILY-IMLCGYPPFYG 1444
>19761
Length = 473
Score = 45.1 bits (105), Expect = 7e-05, Method: Compositional matrix adjust.
Identities = 32/127 (25%), Positives = 61/127 (48%), Gaps = 4/127 (3%)
Frame = -3
Query: 347 QIAEGMAFIEERN--YIHRDLRAANILVSDTLSCKIADFGLARLIED--NEYTAREGAKF 402
Q A + ++ +HRDL+ NI V++ ++ D GLAR + + T++ G
Sbjct: 399 QTASALNYMHTHTPVILHRDLKPQNIYVTEKGDVRLGDLGLARKLTGPADFATSQVGT-- 226
Query: 403 PIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRP 462
I + +PE ++ + KSD+WS G + +I G+ M ++ + G ++ P
Sbjct: 225 -IMYLSPEILSQQPYNSKSDIWSLGCVFYDIT--GKKGSDEMGVMFLLVQVMGGRKLPLP 55
Query: 463 DNCPEEL 469
D+ +E
Sbjct: 54 DHYSQEF 34
>16708
Length = 1397
Score = 44.7 bits (104), Expect = 8e-05, Method: Compositional matrix adjust.
Identities = 35/151 (23%), Positives = 66/151 (43%), Gaps = 7/151 (4%)
Frame = -1
Query: 245 LKLVERLGAGQFGEVWMG-YYNGHTKVAVKSLKQGSMSPDAFLAEANLMKQLQHQRLVRL 303
+ +++ LG G FG+V+ + H K A+K+ S D A + ++
Sbjct: 1397 VAILQVLGKGVFGKVYEARLLSTHEKAALKTSILCHHSLDEVEALGRIEGGFYLAQMFGA 1218
Query: 304 YAVVTQEP-IYIITEYMENGSLVDFLKTPSGIKLTIN-----KLLDMAAQIAEGMAFIEE 357
+ P + I+ + E G L + ++ I + +A Q + I E
Sbjct: 1217 WVTCLPFPKMNILLHFYEMGPLCNVYAHYKNKEMPIRWSNPAMVCCIAGQXVCALEHIHE 1038
Query: 358 RNYIHRDLRAANILVSDTLSCKIADFGLARL 388
+H D++A N+LV +CK+ D+G+A+L
Sbjct: 1037 LGVVHMDVKADNVLVDAHGNCKLTDYGIAQL 945
>37602
Length = 804
Score = 44.3 bits (103), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 22/79 (27%), Positives = 43/79 (54%)
Frame = -1
Query: 305 AVVTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRD 364
+ + +E ++I EY GS+ D LT ++ + + +G+ ++ R +HRD
Sbjct: 315 SYLRREKLWIAMEYCGGGSMQDIYHVTG--PLTEPQIAFVCRETLKGLHYLHRRGKMHRD 142
Query: 365 LRAANILVSDTLSCKIADF 383
++ ANIL+++ K+ADF
Sbjct: 141 IKGANILLTEEGDVKLADF 85
>26560
Length = 398
Score = 43.9 bits (102), Expect = 1e-04, Method: Composition-based stats.
Identities = 29/98 (29%), Positives = 51/98 (52%), Gaps = 1/98 (1%)
Frame = -1
Query: 345 AAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPI 404
AA++ G+ + R ++RDL+ ANIL+ + +I+D GLA A G
Sbjct: 338 AAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGLACDFSKKRPHASVGTH--- 168
Query: 405 KWTAPEAINYG-TFTIKSDVWSFGILLTEIVTHGRIPY 441
+ APE + G ++ +D +SFG +L +++ G P+
Sbjct: 167 GYMAPEVLMKGQSYDSSADWFSFGCMLYKLLK-GHSPF 57
>27405
Length = 532
Score = 42.4 bits (98), Expect = 5e-04, Method: Compositional matrix adjust.
Identities = 35/121 (28%), Positives = 55/121 (45%)
Frame = -3
Query: 304 YAVVTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHR 363
YA T E + I + M G L L + G+ T ++ AA++ G+ + R ++R
Sbjct: 353 YAFQTPEKLCFILDLMNGGDLHYHL-SQHGV-FTEKEVRFYAAEVMLGLEHMHSRFVVYR 180
Query: 364 DLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDV 423
DL+ ANIL+ + +I+D GLA + A G + APE + G S
Sbjct: 179 DLKPANILLDENGHVRISDLGLACDFSKKKPHASVGTH---GYMAPEVLMKGQAYDSSAD 9
Query: 424 W 424
W
Sbjct: 8 W 6
>11185
Length = 473
Score = 42.0 bits (97), Expect = 6e-04, Method: Compositional matrix adjust.
Identities = 31/133 (23%), Positives = 56/133 (42%), Gaps = 21/133 (15%)
Frame = +1
Query: 343 DMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNE-----YTAR 397
D + G+ +I + DLR + +L+ + K ADFGL+++ +N A
Sbjct: 13 DFGIHLVTGLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAE 192
Query: 398 EGAKFPIK----------------WTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPY 441
G ++ I+ + APE +I SD+W+ G + E+ + R+
Sbjct: 193 AGDQWNIQSAEEMMKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSGSRL-- 366
Query: 442 PGMTNPEVIQNLE 454
+PE + LE
Sbjct: 367 SAKPSPEFLNLLE 405
>21433
Length = 590
Score = 41.6 bits (96), Expect = 7e-04, Method: Compositional matrix adjust.
Identities = 25/89 (28%), Positives = 41/89 (46%)
Frame = +2
Query: 347 QIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKW 406
Q++ + + R IHRD++ N+L+ KIADFG + + T G + +
Sbjct: 191 QLSSALEYCHYRKVIHRDIKPENLLLGLKGDLKIADFGWSVHAPSSRRTTMCGT---LDY 361
Query: 407 TAPEAINYGTFTIKSDVWSFGILLTEIVT 435
PE + T D+WS G+L E +
Sbjct: 362 LPPEMVEGKTHDENVDLWSLGVLCYEFLV 448
>12786
Length = 460
Score = 40.4 bits (93), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 30/108 (27%), Positives = 52/108 (48%), Gaps = 22/108 (20%)
Frame = -3
Query: 361 IHRDLRAAN-ILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPI-KWTAPEAINYGT-- 416
IH DL+ AN +LV+ L K+ DFG+A ++ ++ + + ++ + +PEAI
Sbjct: 344 IHSDLKPANFMLVAGNL--KLIDFGIANTLQQDKTSVLKDSRVGTPSYMSPEAIMAACDD 171
Query: 417 ------------------FTIKSDVWSFGILLTEIVTHGRIPYPGMTN 446
++SDVWS G +L +V +GR P+ + N
Sbjct: 170 SADDSMEEDGHRTKPKYKVGVRSDVWSLGCILYNMV-YGRTPFQHIKN 30
>18481
Length = 437
Score = 40.0 bits (92), Expect = 0.002, Method: Composition-based stats.
Identities = 20/64 (31%), Positives = 36/64 (56%), Gaps = 3/64 (4%)
Frame = -1
Query: 335 KLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCK---IADFGLARLIED 391
+ T+ +L ++ Q+ + FI ++ +IHRDL+ N L+ C I DFGL++ +D
Sbjct: 209 RFTLKTILMVSDQLLSRLEFIHQKCFIHRDLKPDNFLMGLGRHCHRLYIIDFGLSKRYKD 30
Query: 392 NEYT 395
+ T
Sbjct: 29 TQGT 18
>28638
Length = 1458
Score = 40.0 bits (92), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 31/111 (27%), Positives = 55/111 (49%), Gaps = 4/111 (3%)
Frame = -1
Query: 329 KTPSGIKLTINKLLDMAAQIAEGMAFIE--ERNYIHRDLRAANILVSD--TLSCKIADFG 384
+T G+ L + + A Q+ + F+ E N IH DL+ NIL+ + + KI DFG
Sbjct: 861 QTLEGVSLNLTR--KFAQQLCTALLFLATPEMNIIHCDLKPENILLCNPKRSAIKIVDFG 688
Query: 385 LARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVT 435
+ + Y + ++F + +PE + + + D+WS G +L E+ T
Sbjct: 687 SSCQLGQRIYQYIQ-SRF---YRSPEVLLGVPYDLAIDMWSLGCILVEMHT 547
>17286
Length = 489
Score = 39.7 bits (91), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 18/60 (30%), Positives = 35/60 (58%)
Frame = +3
Query: 57 PASPLQDNLVIALHSYEPSHDGDLGFEKGEQLRILEQSGEWWKAQSLTTGQEGFIPFNFV 116
P + ++ A++ + P DG+LGF++G+ + ++ Q E W S+ G+ G+ P N+V
Sbjct: 3 PTAGVKQPCARAIYDFLPESDGELGFQEGDMITLISQVDENWFEGSV-HGKVGYFPINYV 179
>29243
Length = 1147
Score = 39.7 bits (91), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 29/100 (29%), Positives = 47/100 (47%), Gaps = 2/100 (2%)
Frame = +2
Query: 114 NFVAKANSLEPEPWFFKNLSRKDAERQLLAPGNTHGSFLIRESES--TAGSFSLSVRDFD 171
++V + SLE W+ + R A++ L + G+FLIR + + G SLS++
Sbjct: 269 DYVNEPCSLESYNWYVGIMERPVAQKXLDTCPD--GTFLIRVTNNPLRRGELSLSIK--- 433
Query: 172 QNQGEVVKHYKIRNLDNGGFYISPRITFPGLHELVRHYTN 211
V+H K+ G FY++ F + LV HY N
Sbjct: 434 --YANAVRHIKVNRNPQGRFYLADGRYFDNIQSLVDHYEN 547
>32264
Length = 287
Score = 39.3 bits (90), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 18/45 (40%), Positives = 27/45 (60%)
Frame = +1
Query: 453 LERGYRMVRPDNCPEELYQLMRLCWKERPEDRPTFDYLRSVLEDF 497
+E GYR+ + P+ +Y+LM CW+ PE RP F L + L+D
Sbjct: 1 IEDGYRLQQNPQTPDSVYKLMLRCWEYVPEKRPHFKELYTSLKDI 135
>27287
Length = 514
Score = 37.0 bits (84), Expect = 0.018, Method: Compositional matrix adjust.
Identities = 15/43 (34%), Positives = 24/43 (55%)
Frame = -2
Query: 459 MVRPDNCPEELYQLMRLCWKERPEDRPTFDYLRSVLEDFFTAT 501
M +P E++ +M CW+E P DRP+F L L+ T++
Sbjct: 513 MKKPPYASSEMFGIMHSCWQEDPNDRPSFSRLVQELDKMLTSS 385
>21210
Length = 518
Score = 36.6 bits (83), Expect = 0.022, Method: Compositional matrix adjust.
Identities = 25/85 (29%), Positives = 42/85 (49%), Gaps = 3/85 (3%)
Frame = +3
Query: 409 PEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNP-EVIQNLERGYRMVRPDN--C 465
P A ++G + ++SDVWS GI L E+ T GR PY + + +Q + RG P +
Sbjct: 42 PRASSHG-YDVRSDVWSLGITLMELAT-GRFPYRKWVSIFDQLQQVVRGVAPCLPHDGAF 215
Query: 466 PEELYQLMRLCWKERPEDRPTFDYL 490
+ + C + + RP ++ L
Sbjct: 216 SHDFVNFVNKCLTKDEKQRPKYNKL 290
>32000
Length = 644
Score = 36.2 bits (82), Expect = 0.031, Method: Compositional matrix adjust.
Identities = 30/97 (30%), Positives = 48/97 (49%), Gaps = 3/97 (3%)
Frame = -1
Query: 375 TLSCKIADFGLARL--IEDNEYTAREGAKFPIKWTAPEAINYGTF-TIKSDVWSFGILLT 431
T KIADFGLAR+ + YT + + APE + F ++ D+WS G +
Sbjct: 581 TAKMKIADFGLARVFGLPVRTYTHEV---ITLWYRAPEILLGCRFYSVPVDIWSLGCIFV 411
Query: 432 EIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDNCPEE 468
E++T R +PG + +++ YR+ R P+E
Sbjct: 410 EMMTR-RALFPGDS------EIDQLYRIFRTLGTPDE 321
>36481
Length = 806
Score = 36.2 bits (82), Expect = 0.032, Method: Compositional matrix adjust.
Identities = 39/154 (25%), Positives = 66/154 (42%), Gaps = 13/154 (8%)
Frame = +2
Query: 235 EDEWEVPRET-----LKLVERLGAGQFGEV--WMGYYNGHTKVAVKSLKQGSMSPDAFLA 287
+D W R T +KL G G FG+V G +A+K +K +A
Sbjct: 323 KDIWCTMRGTSSTNDMKLCPHWGEGTFGKVVQCKDLLKG-DDIALKIIKNVDKYREAAKL 499
Query: 288 EANLMKQLQHQ------RLVRLYAVVTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKL 341
E N++++L+ + V++ I+ +M S+ DFLK S I ++
Sbjct: 500 EINVLEKLREKDPHAKHMCVQMLDWFDYHGHVCISFHMLGLSVFDFLKDNSYGAYPIEQV 679
Query: 342 LDMAAQIAEGMAFIEERNYIHRDLRAANILVSDT 375
++ Q+ + F+ E H DL+ NIL D+
Sbjct: 680 RHISYQLCYAVNFLHENQLTHTDLKPENILFVDS 781
>07933
Length = 728
Score = 35.4 bits (80), Expect = 0.049, Method: Compositional matrix adjust.
Identities = 14/29 (48%), Positives = 16/29 (55%)
Frame = +3
Query: 462 PDNCPEELYQLMRLCWKERPEDRPTFDYL 490
P+ CP LY +M CW P RPTF L
Sbjct: 3 PNYCPNLLYNIMMQCWSAEPSARPTFHKL 89
>38046
Length = 446
Score = 34.7 bits (78), Expect = 0.11, Method: Composition-based stats.
Identities = 14/25 (56%), Positives = 20/25 (80%)
Frame = -1
Query: 348 IAEGMAFIEERNYIHRDLRAANILV 372
IA+ MA++E+ N+IHR+L NILV
Sbjct: 98 IADAMAYMEKENFIHRNLGDRNILV 24
>20559
Length = 430
Score = 34.3 bits (77), Expect = 0.11, Method: Composition-based stats.
Identities = 21/67 (31%), Positives = 37/67 (55%), Gaps = 4/67 (5%)
Frame = -2
Query: 248 VERLGAGQFGEVWMGY-YNGHTKVAVKSLK---QGSMSPDAFLAEANLMKQLQHQRLVRL 303
+E++G G +G V+ H VA+K ++ P + L E L+K+L+H+ +VRL
Sbjct: 360 LEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHRNIVRL 181
Query: 304 YAVVTQE 310
+ V+ E
Sbjct: 180 HDVLHSE 160
>29590
Length = 320
Score = 33.9 bits (76), Expect = 0.17, Method: Composition-based stats.
Identities = 14/41 (34%), Positives = 27/41 (65%)
Frame = +3
Query: 406 WTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTN 446
+ APE ++Y +I++D+WS G+L ++T P+ G+T+
Sbjct: 72 YVAPEVLDYEPLSIQTDMWSLGVLSYVMLTACS-PFVGITS 191
>11228
Length = 2155
Score = 33.1 bits (74), Expect = 0.27, Method: Compositional matrix adjust.
Identities = 20/40 (50%), Positives = 25/40 (62%)
Frame = -1
Query: 127 WFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLS 166
W+ L R AE +LL + GS+L+RESES GSF LS
Sbjct: 1972 WYHGRLGRAGAE-ELLRDQDA-GSYLVRESESKLGSFVLS 1859
>37260
Length = 401
Score = 32.7 bits (73), Expect = 0.39, Method: Composition-based stats.
Identities = 19/69 (27%), Positives = 35/69 (50%)
Frame = -1
Query: 114 NFVAKANSLEPEPWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLSVRDFDQN 173
+F+ L+ W++ LS ++AE +L+ GSFL+R+S + SLS +
Sbjct: 221 DFLESMKQLKDCGWYWGPLSYEEAESKLM--DKRDGSFLVRDSSNENYILSLSFKSMGHV 48
Query: 174 QGEVVKHYK 182
++H+K
Sbjct: 47 HHTRIEHHK 21
>15741
Length = 402
Score = 32.3 bits (72), Expect = 0.53, Method: Composition-based stats.
Identities = 14/42 (33%), Positives = 20/42 (47%)
Frame = -3
Query: 330 TPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANIL 371
T + LT A +A GMA + +HRD+ A N+L
Sbjct: 127 TSTANDLTARDFFSFALHVARGMAHVANNKIVHRDVAARNVL 2
>13664
Length = 507
Score = 32.0 bits (71), Expect = 0.63, Method: Composition-based stats.
Identities = 16/56 (28%), Positives = 27/56 (48%)
Frame = +2
Query: 55 NPPASPLQDNLVIALHSYEPSHDGDLGFEKGEQLRILEQSGEWWKAQSLTTGQEGF 110
+P S + V+AL+ Y+ +L G+ + +L + E W L GQ+GF
Sbjct: 338 SPLGSTRKPKKVVALYDYKAQRSDELTILSGDVIMLLHKDSESWWMGELLDGQQGF 505
>06462
Length = 1511
Score = 30.8 bits (68), Expect = 1.2, Method: Compositional matrix adjust.
Identities = 30/116 (25%), Positives = 48/116 (41%), Gaps = 6/116 (5%)
Frame = +1
Query: 125 EPWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLSVRDFDQNQGEVVKHYKIR 184
E W+ +SR++AE+ L G FL+RES F LS ++ G+ + +
Sbjct: 1090 ELWYHGKMSRREAEKLL----GKDGDFLVRESGHNXSQFVLS----GKHHGQFI---HLL 1236
Query: 185 NLDNGGFYISPRITFPGLHELVRHYTN-----ASDGLCTRLSRPCQTQKPQ-KPWW 234
+D G + F + LV ++ + S G L RP P +P W
Sbjct: 1237 LVDPDGIVRTKDYIFDNISHLVSYHCHHGMPIVSHGSQLTLLRPINVSVPAYRP*W 1404
>20131
Length = 574
Score = 30.8 bits (68), Expect = 1.3, Method: Compositional matrix adjust.
Identities = 15/53 (28%), Positives = 28/53 (52%), Gaps = 1/53 (1%)
Frame = -2
Query: 67 IALHSYEPSHDGDLGFEKGEQLRILEQSGEWWKAQSLTTGQE-GFIPFNFVAK 118
+A++SY DL F +G+ + + ++ +WW T G++ G P +V K
Sbjct: 471 VAMYSYVSGETADLTFNEGDMILVTKKDEDWWTG---TLGEKTGMFPSTYVKK 322
>32357
Length = 625
Score = 30.8 bits (68), Expect = 1.4, Method: Compositional matrix adjust.
Identities = 17/52 (32%), Positives = 33/52 (63%), Gaps = 1/52 (1%)
Frame = -2
Query: 246 KLVERLGAGQFGEVWMGYYN-GHTKVAVKSLKQGSMSPDAFLAEANLMKQLQ 296
+L++++G+G FGE+++G +N +VAVK + + P + E+ L + LQ
Sbjct: 429 RLMKKIGSGSFGEIYLGVHNTSGEEVAVKLELKNAKHPQLYY-ESKLYRVLQ 277
>25100
Length = 699
Score = 28.9 bits (63), Expect = 5.4, Method: Compositional matrix adjust.
Identities = 11/38 (28%), Positives = 19/38 (50%)
Frame = +3
Query: 197 ITFPGLHELVRHYTNASDGLCTRLSRPCQTQKPQKPWW 234
+T+ + L+ +T+ L + SR C+ K K WW
Sbjct: 150 LTYCSSYILIHMHTDTHKDLFLKFSRKCRENKADKIWW 263
>18050
Length = 448
Score = 28.9 bits (63), Expect = 5.8, Method: Compositional matrix adjust.
Identities = 16/57 (28%), Positives = 29/57 (50%), Gaps = 1/57 (1%)
Frame = +3
Query: 66 VIALHSYEPSHDGDLGFEKGEQLRILEQSGE-WWKAQSLTTGQEGFIPFNFVAKANS 121
VIA HSYE L E G+ + + + + W++ + + G G+ P ++ + NS
Sbjct: 24 VIAKHSYESDEPDVLQLELGDVVNVSRKLPDGWYQGERIRDGAVGWFPGSYTEELNS 194
>17516
Length = 453
Score = 28.5 bits (62), Expect = 6.8, Method: Composition-based stats.
Identities = 27/104 (25%), Positives = 50/104 (48%), Gaps = 7/104 (6%)
Frame = -3
Query: 406 WTAPEAI-NYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRM-VRPD 463
+ APE + G + +K+DV+S I+L E+ +G+ +++ + LE + +RP
Sbjct: 421 YMAPEVLLQKGQYDMKADVYSLAIILWEL-WYGQDAADHISS-HLFGRLEDAVQAGLRPS 248
Query: 464 ---NC--PEELYQLMRLCWKERPEDRPTFDYLRSVLEDFFTATE 502
C P++ +L++ W+ RPT EDF T+
Sbjct: 247 VTMTCKPPDDWLKLLQSGWEFHASKRPTSRDAAEFFEDFLERTK 116
>30665
Length = 530
Score = 28.1 bits (61), Expect = 8.0, Method: Compositional matrix adjust.
Identities = 10/19 (52%), Positives = 17/19 (89%)
Frame = +3
Query: 312 IYIITEYMENGSLVDFLKT 330
++++TE+ ENGSL D+LK+
Sbjct: 441 LWLLTEFHENGSLSDYLKS 497
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000340208 | hsapiens_gene_ensembl | X-linked
retinitis pigmentosa GTPase regulator.
[Source:Uniprot/SWISSPROT;Acc:Q92834]
(480 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
02938 299 2e-81
26574 55 8e-08
20162 54 1e-07
12101 48 1e-05
03352 43 3e-04
01451 39 0.004
39525 36 0.028
01786 28 7.7
>02938
Length = 1718
Score = 299 bits (765), Expect = 2e-81, Method: Compositional matrix adjust.
Identities = 165/384 (42%), Positives = 225/384 (58%), Gaps = 1/384 (0%)
Frame = +3
Query: 55 KLYMFGSNNWGQLGLGSKSAISKPTCVKALKPEKVKLAACGRNHTLVSTEGGNVYATGGN 114
+++MFG N++GQLG+G++ ++P+CVK+LK EK +L ACGR+HT+V+TE GN+YA G N
Sbjct: 18 RVFMFGPNDYGQLGIGAQKVANRPSCVKSLKHEKARLVACGRSHTIVATESGNIYAFGAN 197
Query: 115 NEGQLGLGDTEERNTFHVISFFTSEHKIKQLSAGSNTSAALTEDGRLFMWGDNSEGQIGL 174
EGQLG+ E N + + K L+AG + S ALTEDGR+F+WG N EGQ+G+
Sbjct: 198 GEGQLGVEGVTETNLPKQVDSLQAT-PWKMLAAGCDHSLALTEDGRVFVWGGNGEGQLGM 374
Query: 175 KNVSNVCVPQQVTIGKPVSWISCGYYHSAFVTTDGELYVFGEPENGKLGLPNQLLGNHRT 234
S++ VP+Q+ +G+ V+ I+ GYYHSA VT GELY FGE + GKLGL N +T
Sbjct: 375 GEDSDIPVPRQLDVGQSVACIASGYYHSALVTESGELYTFGESDGGKLGL-NGDTDECKT 551
Query: 235 PQLVSEIPEKVIQVACGGEHTVVLTENA-VYXXXXXXXXXXXXXXXXXETSEPKVIENIR 293
PQ V I +KV V+CGG HTV LTE VY E+ P +++
Sbjct: 552 PQQVMAINDKVKSVSCGGSHTVALTEKGEVYAFGEGSSGQLGLGVSTLESESPSLLK--L 725
Query: 294 DQTISYISCGENHTALITDIGLMYTFGDGRHGKLGLGLENFTNHFIPTLCSNFLRFIVKL 353
++ + CGEN T ++++ G +YTFGDGRHGKL LG E+F+N F+ T FL+F VK
Sbjct: 726 PFKVAQVCCGENFTTVVSERGQLYTFGDGRHGKLALGQESFSNQFVCTKVDRFLKFNVKK 905
Query: 354 VACGGCHMVVFAAPHRGVAKEIEFDEINDTCLSVATFLPYSSLTSGNVLQRTLSAXXXXX 413
ACGGCH++V A+P DE + T SLT RT SA
Sbjct: 906 AACGGCHLIVMASPKLENGDVASEDEEEGQIMMNGTIRDSLSLT------RTFSARDRRR 1067
Query: 414 XXXXSPDSFSMRRTLPPIEGTLGL 437
P + RTLPP+ GL
Sbjct: 1068NASPLP----LHRTLPPLGNNRGL 1127
Score = 65.5 bits (158), Expect = 4e-11, Method: Compositional matrix adjust.
Identities = 45/135 (33%), Positives = 65/135 (48%), Gaps = 11/135 (8%)
Frame = +3
Query: 7 LMPDSGAVFTFGKSKFAE----------NNPGKFWFKNDVPVHLSCGDEHSAVVTGNNKL 56
L+ +SG ++TFG+S + P + ND +SCG H+ +T ++
Sbjct: 462 LVTESGELYTFGESDGGKLGLNGDTDECKTPQQVMAINDKVKSVSCGGSHTVALTEKGEV 641
Query: 57 YMFGSNNWGQLGLGSKSAISK-PTCVKALKPEKVKLAACGRNHTLVSTEGGNVYATGGNN 115
Y FG + GQLGLG + S+ P+ +K P KV CG N T V +E G +Y G
Sbjct: 642 YAFGEGSSGQLGLGVSTLESESPSLLKL--PFKVAQVCCGENFTTVVSERGQLYTFGDGR 815
Query: 116 EGQLGLGDTEERNTF 130
G+L LG N F
Sbjct: 816 HGKLALGQESFSNQF 860
Score = 47.8 bits (112), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 41/154 (26%), Positives = 71/154 (46%), Gaps = 15/154 (9%)
Frame = +3
Query: 8 MPDSGAVFTFGKSKFAENNPGKFWFKNDVP---------VHLSCGDEHSAVVTGNNKLYM 58
+ + G V+ FG+ + G +++ P + CG+ + VV+ +LY
Sbjct: 621 LTEKGEVYAFGEGSSGQLGLGVSTLESESPSLLKLPFKVAQVCCGENFTTVVSERGQLYT 800
Query: 59 FGSNNWGQLGLGSKSAISKPTCVKALKPEK--VKLAACGRNHTLV----STEGGNVYATG 112
FG G+L LG +S ++ C K + K VK AACG H +V E G+V A+
Sbjct: 801 FGDGRHGKLALGQESFSNQFVCTKVDRFLKFNVKKAACGGCHLIVMASPKLENGDV-ASE 977
Query: 113 GNNEGQLGLGDTEERNTFHVISFFTSEHKIKQLS 146
EGQ+ + T R++ + F++ + + S
Sbjct: 978 DEEEGQIMMNGT-IRDSLSLTRTFSARDRRRNAS 1076
>26574
Length = 441
Score = 54.7 bits (130), Expect = 8e-08, Method: Composition-based stats.
Identities = 32/96 (33%), Positives = 52/96 (54%)
Frame = +3
Query: 59 FGSNNWGQLGLGSKSAISKPTCVKALKPEKVKLAACGRNHTLVSTEGGNVYATGGNNEGQ 118
+G ++ +LG G+ + +P V AL+ +KV ACG H + T+ G V+ G N+EGQ
Sbjct: 6 WGKGDYHRLGHGTDDHVRRPRRVSALQGKKVIDVACGSLHCVACTDSGEVFTWGDNDEGQ 185
Query: 119 LGLGDTEERNTFHVISFFTSEHKIKQLSAGSNTSAA 154
LG G T +++ + KI +++ GS S A
Sbjct: 186 LGDGTTNAIQRPRMVAALQGK-KINRVACGSAHSLA 290
Score = 53.9 bits (128), Expect = 2e-07, Method: Composition-based stats.
Identities = 23/63 (36%), Positives = 39/63 (61%)
Frame = +3
Query: 38 VHLSCGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKSAISKPTCVKALKPEKVKLAACGRN 97
+ ++CG H T + +++ +G N+ GQLG G+ +AI +P V AL+ +K+ ACG
Sbjct: 99 IDVACGSLHCVACTDSGEVFTWGDNDEGQLGDGTTNAIQRPRMVAALQGKKINRVACGSA 278
Query: 98 HTL 100
H+L
Sbjct: 279 HSL 287
Score = 47.0 bits (110), Expect = 1e-05, Method: Composition-based stats.
Identities = 23/64 (35%), Positives = 36/64 (56%), Gaps = 2/64 (3%)
Frame = +3
Query: 141 KIKQLSAGSNTSAALTEDGRLFMWGDNSEGQIGLKNVSNVCVPQQVTI--GKPVSWISCG 198
K+ ++ GS A T+ G +F WGDN EGQ+G + + P+ V GK ++ ++CG
Sbjct: 93 KVIDVACGSLHCVACTDSGEVFTWGDNDEGQLGDGTTNAIQRPRMVAALQGKKINRVACG 272
Query: 199 YYHS 202
HS
Sbjct: 273 SAHS 284
Score = 41.2 bits (95), Expect = 0.001, Method: Composition-based stats.
Identities = 23/87 (26%), Positives = 43/87 (49%)
Frame = +3
Query: 286 PKVIENIRDQTISYISCGENHTALITDIGLMYTFGDGRHGKLGLGLENFTNHFIPTLCSN 345
P+ + ++ + + ++CG H TD G ++T+GD G+LG G N P + +
Sbjct: 63 PRRVSALQGKKVIDVACGSLHCVACTDSGEVFTWGDNDEGQLGDGTTNAIQR--PRMVAA 236
Query: 346 FLRFIVKLVACGGCHMVVFAAPHRGVA 372
+ VACG H + ++ H+ V+
Sbjct: 237 LQGKKINRVACGSAHSLAWST-HKPVS 314
Score = 33.5 bits (75), Expect = 0.21, Method: Composition-based stats.
Identities = 19/76 (25%), Positives = 34/76 (44%), Gaps = 1/76 (1%)
Frame = +3
Query: 233 RTPQLVSEIP-EKVIQVACGGEHTVVLTENAVYXXXXXXXXXXXXXXXXXETSEPKVIEN 291
R P+ VS + +KVI VACG H V T++ P+++
Sbjct: 57 RRPRRVSALQGKKVIDVACGSLHCVACTDSGEVFTWGDNDEGQLGDGTTNAIQRPRMVAA 236
Query: 292 IRDQTISYISCGENHT 307
++ + I+ ++CG H+
Sbjct: 237 LQGKKINRVACGSAHS 284
>20162
Length = 1121
Score = 53.9 bits (128), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 61/246 (24%), Positives = 95/246 (38%), Gaps = 30/246 (12%)
Frame = +1
Query: 45 EHSAVVTGNNKLYMFGSNNWGQLGLGSKSAI----SKPTCVKALKPEKVKL--------- 91
E S + N LY FG +GQLG S +K + P KV +
Sbjct: 109 EFSTMSDINGNLYSFGCPEYGQLGHNSDGKYFVTSNKMEYKCEMTPRKVSVFIEKTRDGH 288
Query: 92 -----------AACGRNHTLVSTEGGNVYATGGNNEGQLGLGDTEERNTFHVISFFTSEH 140
ACG NHTL+ +++ G G+LG + ++ +I FF
Sbjct: 289 VMPITDVDIREVACGLNHTLIMDSKKRLFSWGFGGYGRLGHAEPKDELVPRLIKFFDGPG 468
Query: 141 K-IKQLSAGSNTSAALTEDGRLFMWGDNS---EGQIGLKNVSNVCVPQQVTIGKPVSWIS 196
+ Q+ GS+ + E G L+ WG + E + K V ++ G V I
Sbjct: 469 RGGSQIQCGSSFCMTVNEHGALYFWGQSKPTGEATMYPKLVQDLS-------GWKVRSIG 627
Query: 197 CGYYHSAFVTTDGELYVFG-EPENGKLGLPNQLLGNHRTPQLVSEIPEKVIQ-VACGGEH 254
C Y S + D + +G P G+LG + + Q V + + VACG H
Sbjct: 628 C-CYRSIVLCADDSVVSWGPSPTYGELGYGENKMKSSTVAQEVKPLDGVYVHDVACGYAH 804
Query: 255 TVVLTE 260
T+++
Sbjct: 805 TLMIAR 822
Score = 31.2 bits (69), Expect = 0.97, Method: Compositional matrix adjust.
Identities = 13/37 (35%), Positives = 23/37 (62%)
Frame = +1
Query: 292 IRDQTISYISCGENHTALITDIGLMYTFGDGRHGKLG 328
I D I ++CG NHT ++ ++++G G +G+LG
Sbjct: 298 ITDVDIREVACGLNHTLIMDSKKRLFSWGFGGYGRLG 408
Score = 30.4 bits (67), Expect = 1.6, Method: Compositional matrix adjust.
Identities = 36/183 (19%), Positives = 67/183 (36%), Gaps = 12/183 (6%)
Frame = +1
Query: 195 ISCGYYHSAFVTTDGELYVFGEPENGKLGLPNQLLGNHRTPQLVSEIPEKVI-------- 246
++CG H+ + + L+ +G G+LG H P+ E+ ++I
Sbjct: 322 VACGLNHTLIMDSKKRLFSWGFGGYGRLG--------HAEPK--DELVPRLIKFFDGPGR 471
Query: 247 ---QVACGGEHTVVLTEN-AVYXXXXXXXXXXXXXXXXXETSEPKVIENIRDQTISYISC 302
Q+ CG + + E+ A+Y T PK+++++ + I C
Sbjct: 472 GGSQIQCGSSFCMTVNEHGALYFWGQSKPTGEA-------TMYPKLVQDLSGWKVRSIGC 630
Query: 303 GENHTALITDIGLMYTFGDGRHGKLGLGLENFTNHFIPTLCSNFLRFIVKLVACGGCHMV 362
L D ++ +G+LG G + + V VACG H +
Sbjct: 631 CYRSIVLCADDSVVSWGPSPTYGELGYGENKMKSSTVAQEVKPLDGVYVHDVACGYAHTL 810
Query: 363 VFA 365
+ A
Sbjct: 811 MIA 819
>12101
Length = 1020
Score = 47.8 bits (112), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 47/154 (30%), Positives = 69/154 (44%), Gaps = 4/154 (2%)
Frame = -2
Query: 56 LYMFGSNNWGQLGLGSKSAISKPTCVKALKPEKVKLAACGRNHTLVSTEGGNVYATGGNN 115
++ G NN+ QL K T VK + + VK A G++HTL+ A G
Sbjct: 860 IWAVGLNNYKQLA-HPKETERFLTPVKT-EIKDVKQIAGGQHHTLILDNNMRCLAVGRPE 687
Query: 116 EGQLGLGDTEERNTFHVISFFTSEHKIKQLSAGSNTSAALTEDGRLFMWGDNSEGQIGLK 175
G+LGLG E T + K+ ++ G S +T DG+L+ WG S Q+G+
Sbjct: 686 YGRLGLGKVTEVVT-KPTAITQLNGKVNYVACGEACSFXITNDGKLYSWGMGSLLQLGVG 510
Query: 176 NVSNVCVPQQV----TIGKPVSWISCGYYHSAFV 205
+ + VP +V T K V G HS F+
Sbjct: 509 DGDDEVVPVEVSSKNTQNKKVLLADGGGQHSVFL 408
Score = 47.4 bits (111), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 46/161 (28%), Positives = 75/161 (46%), Gaps = 5/161 (3%)
Frame = -2
Query: 108 VYATGGNNEGQLGLGDTEERNTFHVISFFTSEHKIKQLSAGSNTSAALTEDGRLFMWGDN 167
++A G NN QL ER + T +KQ++ G + + L + R G
Sbjct: 860 IWAVGLNNYKQLAHPKETER---FLTPVKTEIKDVKQIAGGQHHTLILDNNMRCLAVGRP 690
Query: 168 SEGQIGLKNVSNVCV-PQQVT-IGKPVSWISCGYYHSAFVTTDGELYVFGEPENGKLGLP 225
G++GL V+ V P +T + V++++CG S +T DG+LY +G +LG+
Sbjct: 689 EYGRLGLGKVTEVVTKPTAITQLNGKVNYVACGEACSFXITNDGKLYSWGMGSLLQLGVG 510
Query: 226 NQLLGNHRTPQLVSEI---PEKVIQVACGGEHTVVLTENAV 263
+ + P VS +KV+ GG+H+V L E V
Sbjct: 509 DG--DDEVVPVEVSSKNTQNKKVLLADGGGQHSVFLVEADV 393
Score = 35.8 bits (81), Expect = 0.034, Method: Compositional matrix adjust.
Identities = 33/125 (26%), Positives = 55/125 (44%), Gaps = 3/125 (2%)
Frame = -2
Query: 243 EKVIQVACGGEHTVVLTENAVYXXXXXXXXXXXXXXXXXET-SEPKVIENIRDQTISYIS 301
+ V Q+A G HT++L N E ++P I + + ++Y++
Sbjct: 773 KDVKQIAGGQHHTLILDNNMRCLAVGRPEYGRLGLGKVTEVVTKPTAITQLNGK-VNYVA 597
Query: 302 CGENHTALITDIGLMYTFGDGRHGKLGLGLENFTNHFIPTLCS--NFLRFIVKLVACGGC 359
CGE + IT+ G +Y++G G +LG+G + + +P S N V L GG
Sbjct: 596 CGEACSFXITNDGKLYSWGMGSLLQLGVG--DGDDEVVPVEVSSKNTQNKKVLLADGGGQ 423
Query: 360 HMVVF 364
H V
Sbjct: 422 HSVFL 408
Score = 32.0 bits (71), Expect = 0.58, Method: Compositional matrix adjust.
Identities = 22/68 (32%), Positives = 35/68 (51%), Gaps = 2/68 (2%)
Frame = -2
Query: 39 HLSCGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKSAISKPTCV--KALKPEKVKLAACGR 96
+++CG+ S +T + KLY +G + QLG+G P V K + +KV LA G
Sbjct: 605 YVACGEACSFXITNDGKLYSWGMGSLLQLGVGDGDDEVVPVEVSSKNTQNKKVLLADGGG 426
Query: 97 NHTLVSTE 104
H++ E
Sbjct: 425 QHSVFLVE 402
>03352
Length = 935
Score = 42.7 bits (99), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 38/134 (28%), Positives = 60/134 (44%), Gaps = 10/134 (7%)
Frame = +2
Query: 136 FTSEHKIKQLSAGSNTSAAL--TEDGRLFMWGDNSEGQ-------IGLKNVSNVCVPQQV 186
T KI+Q++ G + AL +DG +F G G+ G + +V + +
Sbjct: 20 ITKSPKIQQVATGHEGAHALMLADDGSVFFVGLAKRGEDGDSGAAKGRRQPKSVKPKKMI 199
Query: 187 TI-GKPVSWISCGYYHSAFVTTDGELYVFGEPENGKLGLPNQLLGNHRTPQLVSEIPEKV 245
+ K V +++C SA VT DGE+Y+FG+ + +H + + V
Sbjct: 200 RVENKQVVFVACNSGSSAVVTKDGEVYMFGK---------DTSHCDHASGHVTDLKDVVV 352
Query: 246 IQVACGGEHTVVLT 259
QVA G HTV LT
Sbjct: 353 TQVALGKAHTVALT 394
Score = 42.0 bits (97), Expect = 5e-04, Method: Compositional matrix adjust.
Identities = 37/130 (28%), Positives = 55/130 (42%), Gaps = 16/130 (12%)
Frame = +2
Query: 7 LMPDSGAVFTFGKSKFAEN---------------NPGKF-WFKNDVPVHLSCGDEHSAVV 50
++ D G+VF G +K E+ P K +N V ++C SAVV
Sbjct: 80 MLADDGSVFFVGLAKRGEDGDSGAAKGRRQPKSVKPKKMIRVENKQVVFVACNSGSSAVV 259
Query: 51 TGNNKLYMFGSNNWGQLGLGSKSAISKPTCVKALKPEKVKLAACGRNHTLVSTEGGNVYA 110
T + ++YMFG + + V LK V A G+ HT+ T G ++
Sbjct: 260 TKDGEVYMFGKD--------TSHCDHASGHVTDLKDVVVTQVALGKAHTVALTSKGQLFT 415
Query: 111 TGGNNEGQLG 120
G NN+GQ G
Sbjct: 416 FGINNKGQCG 445
Score = 36.6 bits (83), Expect = 0.026, Method: Compositional matrix adjust.
Identities = 32/137 (23%), Positives = 56/137 (40%), Gaps = 9/137 (6%)
Frame = +2
Query: 201 HSAFVTTDGELYVFGEPENGKLGLPNQLLGNHRTPQLVSEIPEKVIQV--------AC-G 251
H+ + DG ++ G + G+ G G R P+ V P+K+I+V AC
Sbjct: 71 HALMLADDGSVFFVGLAKRGEDGDSGAAKG-RRQPKSVK--PKKMIRVENKQVVFVACNS 241
Query: 252 GEHTVVLTENAVYXXXXXXXXXXXXXXXXXETSEPKVIENIRDQTISYISCGENHTALIT 311
G VV + VY + +++D ++ ++ G+ HT +T
Sbjct: 242 GSSAVVTKDGEVYMFGKDTSHCDHASGH---------VTDLKDVVVTQVALGKAHTVALT 394
Query: 312 DIGLMYTFGDGRHGKLG 328
G ++TFG G+ G
Sbjct: 395 SKGQLFTFGINNKGQCG 445
>01451
Length = 1229
Score = 39.3 bits (90), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 18/49 (36%), Positives = 27/49 (55%)
Frame = -3
Query: 289 IENIRDQTISYISCGENHTALITDIGLMYTFGDGRHGKLGLGLENFTNH 337
IE + D + I+ G +H A +TD+G +YT G G+LG E F+
Sbjct: 1179 IEVLPDAVVVKIASGSDHIACLTDLGELYTLGCAEQGQLGRVAECFSTR 1033
>39525
Length = 450
Score = 36.2 bits (82), Expect = 0.028, Method: Composition-based stats.
Identities = 13/38 (34%), Positives = 27/38 (71%), Gaps = 2/38 (5%)
Frame = -3
Query: 141 KIKQLSAGSNTS--AALTEDGRLFMWGDNSEGQIGLKN 176
K++ +++G N A+T++G+++ WG N +GQ+GL +
Sbjct: 163 KVRTIASGCNACHCVAITDEGKVYTWGRNEKGQLGLSD 50
Score = 32.0 bits (71), Expect = 0.62, Method: Composition-based stats.
Identities = 17/41 (41%), Positives = 24/41 (58%)
Frame = -3
Query: 289 IENIRDQTISYISCGENHTALITDIGLMYTFGDGRHGKLGL 329
+E I+ +TI+ C H ITD G +YT+G G+LGL
Sbjct: 175 LEGIKVRTIAS-GCNACHCVAITDEGKVYTWGRNEKGQLGL 56
Score = 28.5 bits (62), Expect = 6.5, Method: Composition-based stats.
Identities = 12/28 (42%), Positives = 15/28 (53%)
Frame = -3
Query: 42 CGDEHSAVVTGNNKLYMFGSNNWGQLGL 69
C H +T K+Y +G N GQLGL
Sbjct: 139 CNACHCVAITDEGKVYTWGRNEKGQLGL 56
>01786
Length = 1290
Score = 28.1 bits (61), Expect = 7.7, Method: Compositional matrix adjust.
Identities = 14/36 (38%), Positives = 20/36 (55%)
Frame = +3
Query: 217 PENGKLGLPNQLLGNHRTPQLVSEIPEKVIQVACGG 252
P N KL +P +L G+ RT + +S K + V C G
Sbjct: 945 PSNSKLCIPQELSGHTRTVRSLSNCLVKCVLVDCNG 1052
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000381387 | hsapiens_gene_ensembl | Proto-oncogene
tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK) (Lymphocyte
cell-specific protein-tyrosine kinase) (LSK) (T cell- specific
protein-tyrosine kinase). [Source:Uniprot/SWISSPROT;Acc:P06239]
(509 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
06405 298 2e-81
21808 283 4e-77
11780 206 7e-73
04852 161 5e-40
09007 157 7e-39
07291 138 5e-33
17300 122 3e-31
20640 124 8e-29
14116 121 7e-28
07940 110 1e-24
18996 107 9e-24
17637 105 5e-23
22005 84 7e-23
08294 104 1e-22
14477 94 1e-19
01718 91 1e-18
19301 86 4e-17
13305 84 1e-16
13592 78 9e-15
18921 77 1e-14
12721 77 1e-14
07833 77 2e-14
01060 76 3e-14
29581 75 6e-14
17253 73 3e-13
14126 72 4e-13
01707 72 6e-13
01756 69 6e-12
00300 68 8e-12
00715 67 2e-11
01966 65 6e-11
14420 65 9e-11
27546 64 1e-10
18484 63 2e-10
12672 63 2e-10
25550 60 1e-09
04591 60 2e-09
07836 59 3e-09
31885 57 2e-08
17975 57 3e-08
13066 56 3e-08
19094 55 7e-08
09606 55 9e-08
03240 54 1e-07
21079 51 1e-06
30755 51 1e-06
15910 50 3e-06
04138 49 4e-06
13212 49 4e-06
26711 47 2e-05
35671 47 3e-05
01392 45 5e-05
19761 45 7e-05
16708 45 8e-05
37602 44 1e-04
26560 44 1e-04
27405 42 5e-04
11185 42 6e-04
21433 42 7e-04
12786 40 0.002
18481 40 0.002
28638 40 0.002
17286 40 0.003
29243 40 0.003
32264 39 0.003
27287 37 0.018
21210 37 0.022
32000 36 0.031
36481 36 0.032
07933 35 0.049
38046 35 0.11
20559 34 0.11
29590 34 0.17
11228 33 0.27
37260 33 0.39
15741 32 0.53
13664 32 0.63
06462 31 1.2
20131 31 1.3
32357 31 1.4
25100 29 5.4
18050 29 5.8
17516 28 6.8
30665 28 8.0
>06405
Length = 1965
Score = 298 bits (764), Expect = 2e-81, Method: Compositional matrix adjust.
Identities = 161/352 (45%), Positives = 229/352 (65%), Gaps = 8/352 (2%)
Frame = +1
Query: 155 ESESTAGSFSLSVRDFDQNQGEVVKHYKIRNLDNGGFYISPRITFPGLHELVRHYTNASD 214
ESES+ G S+SVR F+ V HY+I D+G +++ F L ELV H++ +D
Sbjct: 1 ESESSPGQRSISVR-FEGR----VYHYRITE-DDGKVFVTQEHRFNTLAELVHHHSIHAD 162
Query: 215 GLCTRLSRPCQTQKPQKPWW------EDEWEVPRETLKLVERLGAGQFGEVWMGYYNGHT 268
GL T L P K QKP D WE+ R + + RLG GQ+G+V+ + +
Sbjct: 163 GLVTTLLYPAP--KRQKPTVFGVSPEPDRWEIERTEIAMKHRLGGGQYGDVYEAMWKRYN 336
Query: 269 K-VAVKSLKQGSMSPDAFLAEANLMKQLQHQRLVRLYAVVTQEP-IYIITEYMENGSLVD 326
K VAVK+LK+ +M+ + FL EA +MK+++H LV+L V T+EP YI+TE+M +G+L+D
Sbjct: 337 KIVAVKTLKEDTMALNDFLEEAAIMKEMKHPNLVQLLGVCTREPPFYIVTEFMPHGNLLD 516
Query: 327 FLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLA 386
+L++ + + L+ MA QIA GMA++E +N+IHRDL A N LV+D+ K+ADFGLA
Sbjct: 517 YLRSSTREENGPTALMYMATQIASGMAYLETKNFIHRDLAARNCLVADSNMVKVADFGLA 696
Query: 387 RLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTN 446
RL++D+ YTA GAKFPIKWTAPE + + F+ +SD+W+FG+LL E+ T+G PYPG+
Sbjct: 697 RLMKDDTYTAHIGAKFPIKWTAPEGLAFNRFSTRSDIWAFGVLLWELATYGMSPYPGVEL 876
Query: 447 PEVIQNLERGYRMVRPDNCPEELYQLMRLCWKERPEDRPTFDYLRSVLEDFF 498
EV LERGYRM RP P ++Y LM CW+ P+DRPTF + +LE+ F
Sbjct: 877 TEVYHLLERGYRMERPPGTPADVYILMLKCWQWDPKDRPTFKEIHFLLENMF 1032
>21808
Length = 1011
Score = 283 bits (725), Expect(2) = 4e-77, Method: Compositional matrix adjust.
Identities = 138/225 (61%), Positives = 175/225 (77%), Gaps = 1/225 (0%)
Frame = +1
Query: 262 GYYNGHTKVAVKSLKQGSMSPDAFLAEANLMKQLQHQRLVRLYAVVTQE-PIYIITEYME 320
G +N T VA+K+LK G+M P FLAEA +MK+L+H +L++LYAV TQ+ PI+IITE M+
Sbjct: 4 GLWNNTTPVAIKTLKSGTMDPKDFLAEAQIMKKLRHPKLIQLYAVCTQDDPIFIITELMK 183
Query: 321 NGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKI 380
NGSL++FL+ G L + L+D+ AQIA GMA++E +NYIHRDL A NILVSD + KI
Sbjct: 184 NGSLLEFLQG-KGRVLKLPALIDIGAQIACGMAYLESQNYIHRDLAARNILVSDNNTVKI 360
Query: 381 ADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIP 440
ADFGLAR+I+++EY AR GA+FPIKWTAPEA NY FTIKSDVWSFGILLTE VT+GR+P
Sbjct: 361 ADFGLARVIKEDEYEARVGARFPIKWTAPEAANYNRFTIKSDVWSFGILLTETVTYGRVP 540
Query: 441 YPGMTNPEVIQNLERGYRMVRPDNCPEELYQLMRLCWKERPEDRP 485
YPGMTN EV+ +E GYRM P CP+ LY +M CW++ +RP
Sbjct: 541 YPGMTNAEVLHQVEHGYRMPCPPGCPKPLYDIMLECWRKEEMERP 675
Score = 23.1 bits (48), Expect(2) = 4e-77, Method: Compositional matrix adjust.
Identities = 10/22 (45%), Positives = 14/22 (63%)
Frame = +2
Query: 485 PTFDYLRSVLEDFFTATEGQYQ 506
PTF+ L+ LE+FFT Y+
Sbjct: 674 PTFETLQWKLEEFFTMDSKDYR 739
>11780
Length = 1713
Score = 206 bits (523), Expect(2) = 7e-73, Method: Compositional matrix adjust.
Identities = 126/341 (36%), Positives = 189/341 (55%), Gaps = 10/341 (2%)
Frame = +3
Query: 82 FEKGEQLRILEQSGE--WWKAQSLTTGQEGFIPFNFVA--KANSLEPEPWFFKNLSRKDA 137
F+KG+ L I + + W+KA + G+EG IP N+V K +L PWF ++R+ A
Sbjct: 111 FQKGDLLVIRRATSDRMWYKACD-SNGREGMIPANYVQPRKVVTLHAMPWFHGKITRQQA 287
Query: 138 ERQLLAPGNTHGSFLIRESESTAGSFSLSVRDFDQNQGEVVKHYKIRNLDNGGFYISPRI 197
E +LL P G FLIRES + G ++L V + V+HY+I +N I
Sbjct: 288 E-ELLKP-REDGLFLIRESSNYPGDYTLCVCHLGK-----VEHYRILYRENQ-LTIDEEG 443
Query: 198 TFPGLHELVRHYTNASDGLCTRLSRPCQTQKPQ------KPWWEDEWEVPRETLKLVERL 251
F L ELV+HY +DGLCT+L+RP Q + + W + + L++ E +
Sbjct: 444 FFRNLDELVKHYLADADGLCTQLTRPVTKQGGNFGTVSLQEFKSGGWVIAXQDLEIGEAI 623
Query: 252 GAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPDAFLAEANLMKQLQHQRLVRLYAVVTQEP 311
G G FG+V+ G Y G VA+K LK +FL EA++M L+H LVRL VV E
Sbjct: 624 GKGDFGDVYKGMYRGQP-VAIKQLKDKDRGEQSFLQEASVMTSLRHDNLVRLIGVVLGET 800
Query: 312 IYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANIL 371
I+++TE+M G+LV++L++ +T ++ A M ++E + +HRDL A N+L
Sbjct: 801 IFLVTEFMGKGNLVEYLRSRGRSVITKKDQINFATDTCAAMEYLESKRLVHRDLAARNVL 980
Query: 372 VSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAI 412
V D K++DFGLA+ + ++ + KFPIKWTAPEA+
Sbjct: 981 VHDDGKAKVSDFGLAKFGDFSQTS----VKFPIKWTAPEAL 1091
Score = 87.0 bits (214), Expect(2) = 7e-73, Method: Compositional matrix adjust.
Identities = 39/80 (48%), Positives = 56/80 (70%)
Frame = +1
Query: 417 FTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDNCPEELYQLMRLC 476
FT KSD+WSFGILL EI + GR+PYP + +V+ ++ERGYRM P+ CP E+Y +M+
Sbjct: 1105 FTSKSDMWSFGILLWEIYSFGRVPYPRIPLTDVVMHVERGYRMEAPEGCPPEIYSIMKQA 1284
Query: 477 WKERPEDRPTFDYLRSVLED 496
W+ P +RPTF + + L +
Sbjct: 1285 WELDPNERPTFKSVLARLNN 1344
>04852
Length = 1462
Score = 161 bits (408), Expect = 5e-40, Method: Compositional matrix adjust.
Identities = 98/254 (38%), Positives = 133/254 (52%), Gaps = 31/254 (12%)
Frame = +1
Query: 268 TKVAVKSLKQ--GSMSPDAFLAEANLMKQLQ----HQRLVRLYAVVTQE-PIYIITEYME 320
+ VAVK L+ ++ F+ E +MK ++ H +V TQ P+++I E+ +
Sbjct: 22 STVAVKMLRDIVTAVEEQDFVQELQVMKAVKKMGSHINIVNFLGCCTQGGPLWVIVEFAK 201
Query: 321 NGSLVDFL-----------------------KTPSGIKLTINKLLDMAAQIAEGMAFIEE 357
NG+L DFL KTP G + LL A QIA GM F+
Sbjct: 202 NGNLRDFLESCRDGINGYGKFVSPQDPGWYTKTPGGHVIRRKNLLSYAFQIARGMEFLAS 381
Query: 358 RNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTF 417
R IHRDL A N+LV++ KIADFGL+R + Y R G + P+KW APEA+ +
Sbjct: 382 RKCIHRDLAARNVLVTEEHVLKIADFGLSR--TGDYYKKRSGGRLPVKWMAPEALFDMRY 555
Query: 418 TIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQN-LERGYRMVRPDNCPEELYQLMRLC 476
T KSDVWSFG++L EI + G +PY + N E+ L+ YRM RP+ LY +M C
Sbjct: 556 TTKSDVWSFGVVLWEIFSLGGMPYASIPNEELYSKLLDDAYRMPRPELASGNLYAIMERC 735
Query: 477 WKERPEDRPTFDYL 490
W RP DRP F L
Sbjct: 736 WLNRPSDRPEFSQL 777
>09007
Length = 1440
Score = 157 bits (398), Expect = 7e-39, Method: Compositional matrix adjust.
Identities = 88/266 (33%), Positives = 145/266 (54%), Gaps = 15/266 (5%)
Frame = -1
Query: 240 VPRETLKLVERLGAGQFGEV----WMGYYNGHTKVAVKSLKQGSMSPDA--FLAEANLMK 293
+ ++ + L + LG G FG V W +VAVK L + + D FL E +M+
Sbjct: 888 ISKDCVALSKSLGQGHFGTVRQAIWTAESGEKVQVAVKCLSKDKIHKDGQEFLKETAIMQ 709
Query: 294 QLQHQRLVRLYAVVTQE--PIYIITEYMENGSLVDFLKTPSG-IKLTINKLLDMAAQIAE 350
L H+ +VR+Y VV I ++TE SL++ +K S + ++ +L D + Q+ +
Sbjct: 708 MLDHENIVRVYGVVMDNGADIMLVTELAPMRSLLECVKEVSARVDFSVPRLCDFSQQVCD 529
Query: 351 GMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLA-RLIEDNEYTAREGA---KFPIKW 406
GM+++E + +HRDL A NIL+ KI+D G++ L EY + + + W
Sbjct: 528 GMSYLESKRLVHRDLAARNILLFSKSKVKISDVGVSGALGAGKEYYQSQQTIHLQNAVAW 349
Query: 407 TAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLE--RGYRMVRPDN 464
APE+ F+ SDVW+FG+LL E THG P+ G+ ++++ ++ + R+ +PD
Sbjct: 348 CAPESFRNLCFSSASDVWAFGVLLWEFFTHGFQPWAGLNGQQIMEAVDAPQSQRLEQPDL 169
Query: 465 CPEELYQLMRLCWKERPEDRPTFDYL 490
CP+E Y +M CW++ P+ RPTF L
Sbjct: 168 CPKEYYAVMLKCWEQEPQRRPTFSQL 91
>07291
Length = 833
Score = 138 bits (348), Expect = 5e-33, Method: Compositional matrix adjust.
Identities = 67/164 (40%), Positives = 104/164 (63%), Gaps = 2/164 (1%)
Frame = +1
Query: 336 LTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLA-RLIEDNEY 394
LT+ +LLD QIA+GMA+++E +HR+L A N +V++ +++D+G+ L + Y
Sbjct: 40 LTVVQLLDFGRQIADGMAYLQEVKVVHRNLAARNCIVTEDGRLQLSDYGVTGSLFPQSYY 219
Query: 395 TAREG-AKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNL 453
TA + A+ +KW APE I+ F+ KSDVW+FG++L E++T G PYP + N ++ L
Sbjct: 220 TADDSPARDLVKWMAPETIDNFHFSSKSDVWAFGVVLWELLTRGITPYPDVENSSLLPYL 399
Query: 454 ERGYRMVRPDNCPEELYQLMRLCWKERPEDRPTFDYLRSVLEDF 497
+ G+RM +P PE +Y++M CW E PE RP F L L+ F
Sbjct: 400 KEGHRMKKPKQSPEPVYEMMTACWNESPEQRPDFAELNDQLKTF 531
>17300
Length = 480
Score = 122 bits (307), Expect(2) = 3e-31, Method: Compositional matrix adjust.
Identities = 57/116 (49%), Positives = 82/116 (70%), Gaps = 4/116 (3%)
Frame = +1
Query: 348 IAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDN----EYTAREGAKFP 403
I+ GM + + Y+HRDL A NILV++ L CK+ADFGL+R IE + YT + G K P
Sbjct: 1 ISSGMGXLADMGYVHRDLAARNILVNEILVCKVADFGLSREIESDTTEGAYTTK-GGKIP 177
Query: 404 IKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRM 459
++WTAPEAI Y FT SDVWSFG+++ E++++G PY +N +VI+ +E+GYR+
Sbjct: 178 VRWTAPEAIAYRKFTSASDVWSFGVVMWEVMSYGERPYWNWSNQDVIKAVEKGYRL 345
Score = 30.8 bits (68), Expect(2) = 3e-31, Method: Composition-based stats.
Identities = 13/39 (33%), Positives = 19/39 (48%)
Frame = +2
Query: 464 NCPEELYQLMRLCWKERPEDRPTFDYLRSVLEDFFTATE 502
+CPE L+QLM W++ RP + L+ A E
Sbjct: 356 DCPEALHQLMLDAWQKERSHRPKMSMVVKTLDKLIRAPE 472
>20640
Length = 1492
Score = 124 bits (311), Expect = 8e-29, Method: Compositional matrix adjust.
Identities = 61/146 (41%), Positives = 84/146 (57%), Gaps = 1/146 (0%)
Frame = +1
Query: 358 RNYIHRDLRAANILVSDTLSCKIADFGLARLIED-NEYTAREGAKFPIKWTAPEAINYGT 416
R Y+HRDL N LV L KI+DFGLAR + + Y E PI+W EAI Y
Sbjct: 1 RGYVHRDLATRNCLVGHDLVVKISDFGLARSVHSVDYYRGSEHDAIPIRWMPLEAILYNK 180
Query: 417 FTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDNCPEELYQLMRLC 476
F+ +SDVWSFG++L EI PY G+T+ EV++ ++ G + P+ P +Y+LM+ C
Sbjct: 181 FSTQSDVWSFGVVLWEIFAFALQPYYGLTHEEVVRFVKEGKVLACPERTPPPMYELMKQC 360
Query: 477 WKERPEDRPTFDYLRSVLEDFFTATE 502
W RP RP+F L LE+ + E
Sbjct: 361 WHRRPATRPSFHTLHKTLENMHSKYE 438
>14116
Length = 1017
Score = 121 bits (303), Expect = 7e-28, Method: Compositional matrix adjust.
Identities = 72/216 (33%), Positives = 117/216 (54%), Gaps = 13/216 (6%)
Frame = -1
Query: 240 VPRETLKLVERLGAGQFGEVWMGYYN-----GHTKVAVKSLKQGS---MSPDAFLAEANL 291
+ RE L + E +G G FG V G+ G VAVK+L + + +FL EA +
Sbjct: 645 IDREFLTMGEEIGKGNFGCVKRGFLTLPEQKGDILVAVKTLHNNNPREIELQSFLQEALI 466
Query: 292 MKQLQHQRLVRLYAV---VTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQI 348
MK H ++ L + + P+ ++ +M++G L+ +++ + TI L+ I
Sbjct: 465 MKDFHHSNVLTLIGICLNLDDMPL-VVLPFMKHGDLLTYIRDDQH-QPTIKDLIMYGVDI 292
Query: 349 AEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREG--AKFPIKW 406
A GM ++ ++HRDL A N ++ + K+ADFGLAR I + EY + E AK P+KW
Sbjct: 291 ARGMDYLAGLKFVHRDLAARNCMLDEDFHVKVADFGLARDIYEKEYYSSENKKAKLPVKW 112
Query: 407 TAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYP 442
A E++ G + K+DVWS+G++L E++T G P
Sbjct: 111 MALESLEKGNYDSKTDVWSYGVVLWELLTRGSDALP 4
>07940
Length = 1336
Score = 110 bits (276), Expect = 1e-24, Method: Compositional matrix adjust.
Identities = 84/278 (30%), Positives = 127/278 (45%), Gaps = 70/278 (25%)
Frame = -3
Query: 237 EWEVPRETLKLVERLGAGQFGEVW----MGYY--NGHTKVAVKSLKQGSMSPDA--FLAE 288
+WE PRE L L +RLG G FG V MG + N VAVK LK+ + + + E
Sbjct: 860 KWEFPRERLVLGDRLGEGAFGLVMKGEAMGIFKDNNSVTVAVKMLKEDATDREMMDLIRE 681
Query: 289 ANLMKQL-QHQRLVRL----------YAVVTQEPIYIITEYMEN---------------- 321
+MK + +H+ ++ L Y +V P + +++++
Sbjct: 680 MEMMKVIGKHKNIINLLGCCTQRGALYVIVEFAPHGNLRDFLKSHRPHGTSYSCIADYEQ 501
Query: 322 ---------------------GSLVDFLKTPSGIK-------------LTINKLLDMAAQ 347
G+ + F+ S + LT L+ A Q
Sbjct: 500 PVITSSSSSFSHPNSASSSAQGTSLGFIPGTSTVSFSTGSHRQDMLKMLTPKDLISYAYQ 321
Query: 348 IAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTARE-GAKFPIKW 406
+A GM ++ + IHRDL A N+LV++ KIADFGL R ++ +Y + + P+KW
Sbjct: 320 VARGMEYLASKQCIHRDLAARNVLVAEEYVLKIADFGLTRNLQQFDYYRKTTDGRLPVKW 141
Query: 407 TAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGM 444
APEA+ +T KSDVWS+G+LL EI T G PYP +
Sbjct: 140 MAPEALFDRKYTSKSDVWSYGVLLWEIFTLGGNPYPSV 27
>18996
Length = 491
Score = 107 bits (268), Expect = 9e-24, Method: Compositional matrix adjust.
Identities = 65/158 (41%), Positives = 87/158 (55%), Gaps = 10/158 (6%)
Frame = +2
Query: 361 IHRDLRAANILVSDTLSCKIADFGLARLIE-DNEYTAREGAKFPIKWTAPEAINYGTFTI 419
IHRDL A NILV D KI+DFGLA+ D Y PIKW +PEAI F+
Sbjct: 2 IHRDLAARNILV-DRSCVKISDFGLAQFANADGYYYGISQRDIPIKWYSPEAIETCKFSS 178
Query: 420 KSDVWSFGILLTEIVTHGRIP--YPG--MTNPEVIQNLERGYRMVRPDNCPEELY-QLMR 474
SDVWS+G+ L E+ + G IP PG +T E + L +G R+ +P+ C + +Y +LMR
Sbjct: 179 YSDVWSYGVTLFEMFSRGEIPNLLPGHDLTQEEFLNRLRKGERLPKPELCSDFVYSELMR 358
Query: 475 LCWKERPEDRPTFDYLRSVLE----DFFTATEGQYQPQ 508
CW E P+ RPTF + ++ D + G Q Q
Sbjct: 359 PCWHEMPKSRPTFHQIIQIIAREMGDNISGXAGSTQQQ 472
>17637
Length = 447
Score = 105 bits (261), Expect = 5e-23, Method: Compositional matrix adjust.
Identities = 50/132 (37%), Positives = 77/132 (58%), Gaps = 1/132 (0%)
Frame = +1
Query: 369 NILVSDTLSCKIADFGLARLIEDNEYTAR-EGAKFPIKWTAPEAINYGTFTIKSDVWSFG 427
N ++ D L K+ D L+R + +Y +G PIKW + EA+ + SDVWSFG
Sbjct: 1 NCVIDDQLRVKLTDSALSRDLFSGDYNCLGDGEYRPIKWLSLEALQKSHYNEGSDVWSFG 180
Query: 428 ILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDNCPEELYQLMRLCWKERPEDRPTF 487
+L+ E+ T G++PY + E+ L+ GYR+ +P NCP+EL+ +M CW P +RP+F
Sbjct: 181 VLMWEMCTLGKLPYAEIDPYEMEHYLKDGYRLAQPFNCPDELFTIMAYCWASMPAERPSF 360
Query: 488 DYLRSVLEDFFT 499
L+ L +F T
Sbjct: 361 SQLQICLSEFHT 396
>22005
Length = 873
Score = 83.6 bits (205), Expect(2) = 7e-23, Method: Compositional matrix adjust.
Identities = 61/194 (31%), Positives = 93/194 (47%), Gaps = 44/194 (22%)
Frame = +1
Query: 285 FLAEANLMKQLQHQRLVRLYAVVT-QEPIYIITEYMENGSLVDFLK--TPSGIKLTI--- 338
F EA+LM H +V+L V +P+ ++ E+M G L DFL+ +P L +
Sbjct: 151 FEREASLMADFDHPNIVKLLGVCAIGKPMCLLFEFMSKGDLNDFLRLCSPENYNLPVSRS 330
Query: 339 -NKLLDM------------------------------------AAQIAEGMAFIEERNYI 361
N ++D+ + QI+ GMA++ +++Y+
Sbjct: 331 QNLVVDLEDGLRVEVEAEECEKDTQSEDRDCSGMLXTKDQLYISQQISAGMAYLAQKDYV 510
Query: 362 HRDLRAANILVSDTLSCKIADFGLARLIED-NEYTAREGAKFPIKWTAPEAINYGTFTIK 420
HRDL A + S T I+DFGLAR + + Y E PI+W EAI Y F+ +
Sbjct: 511 HRDL-ATRTVXSRTT*S*ISDFGLARSVHSVDYYRGSEQDAIPIRWMPLEAILYSKFSTQ 687
Query: 421 SDVWSFGILLTEIV 434
SDVWSFG++L EI+
Sbjct: 688 SDVWSFGVVLWEIL 729
Score = 42.0 bits (97), Expect(2) = 7e-23, Method: Compositional matrix adjust.
Identities = 16/42 (38%), Positives = 28/42 (66%)
Frame = +3
Query: 440 PYPGMTNPEVIQNLERGYRMVRPDNCPEELYQLMRLCWKERP 481
PY G+T+ EV+ ++ G + +P P ++Y+LM+ CW+ RP
Sbjct: 744 PYYGLTHEEVVNYVKAGKILEQPTKTPHQVYELMKQCWQRRP 869
>08294
Length = 1849
Score = 104 bits (259), Expect = 1e-22, Method: Compositional matrix adjust.
Identities = 58/198 (29%), Positives = 100/198 (50%), Gaps = 13/198 (6%)
Frame = +2
Query: 310 EPIYIITEYMENGSLVDFL-------------KTPSGIKLTINKLLDMAAQIAEGMAFIE 356
EP ++ITEY + G L FL + P+ L +++ L M Q+A GM +
Sbjct: 926 EPHFLITEYCDWGDLKQFLLATRNDNGRGRGTRVPA---LALSQKLGMGQQVAAGMEALS 1096
Query: 357 ERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGT 416
+ +H DL A N+L++ + K+A L+ + +EY P++W PE + +
Sbjct: 1097 NQGLVHGDLAARNVLLTSRMQLKVARPALSGDVYASEYYPLHQRLVPLRWLPPEGVLEDS 1276
Query: 417 FTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDNCPEELYQLMRLC 476
T DVW+FG+ L E++ +PY M++ EV+++L+ + + P L L++ C
Sbjct: 1277 ATTCGDVWAFGVFLWEVLQLADLPYRLMSDEEVLRSLQHSQAALDSPDAPPALLSLLQRC 1456
Query: 477 WKERPEDRPTFDYLRSVL 494
++P RP F + SVL
Sbjct: 1457 TAQQPSQRPPFSEICSVL 1510
>14477
Length = 493
Score = 94.0 bits (232), Expect = 1e-19, Method: Composition-based stats.
Identities = 54/158 (34%), Positives = 87/158 (55%), Gaps = 8/158 (5%)
Frame = -1
Query: 250 RLGAGQFGEVWMGYY---NGHTKVAVKSLKQGSMSPDA---FLAEANLMKQLQHQRLVRL 303
+LGAG FG V G + VA+K LK + P + EA +MK++ H +VRL
Sbjct: 469 KLGAGNFGSVMKGVCRLDDREIPVAIKVLKNADLDPSVQSELIKEAEVMKKMDHMHIVRL 290
Query: 304 YAVVTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHR 363
+ E + ++ E + G L FL P L + +L++ Q+++GM ++E ++HR
Sbjct: 289 IGLCEGETMMLVLELAKLGPLNKFL--PKNKHLPLWNILELMWQVSQGMEYLEANKFVHR 116
Query: 364 DLRAANILVSDTLSCKIADFGLARLI--EDNEYTAREG 399
DL A NIL+ D KI+DFG+++ + E+N Y A+E
Sbjct: 115 DLAARNILLCDEHFAKISDFGMSKTLSRENNYYMAQEA 2
>01718
Length = 959
Score = 90.9 bits (224), Expect = 1e-18, Method: Compositional matrix adjust.
Identities = 70/252 (27%), Positives = 120/252 (47%), Gaps = 13/252 (5%)
Frame = +3
Query: 247 LVERLGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPDAFLAEANLMKQLQHQRLVRLYAV 306
+ E++GAG F EV+ + +V + + + L E L+ +LQH ++R V
Sbjct: 159 ICEKIGAGFFSEVFKVTHRITGQVMALKMNTMTSNRHNMLREVQLLNRLQHANILRFMGV 338
Query: 307 VTQE-PIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDL 365
E ++ +TEY+ +G+L L+ +L + + + +A G+ ++ +IHRDL
Sbjct: 339 CVHEGQLHALTEYIPSGNLEQLLEKKDE-ELPWTQRIQLTLGLARGLDYLHSTRFIHRDL 515
Query: 366 RAANILV----SDTLSCKIADFGLARLIE---DNEYTAREGAKFPIKWTAPEAINYGTFT 418
+ NIL+ + IADFGLA I D E G+ + W APE +N +
Sbjct: 516 TSKNILIRREDNHGYHAVIADFGLATKIPDPLDKEKLPTVGSPY---WMAPEVLNGHFYN 686
Query: 419 IKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLER-GYRMVRPDN----CPEELYQLM 473
++D++S GI++ EI RIP +P+++ + G V CP + QL
Sbjct: 687 ERADLFSVGIIMCEIT--ARIP----ADPDIMPRMNNFGVDYVALSEMISYCPLDYLQLA 848
Query: 474 RLCWKERPEDRP 485
C + P+ RP
Sbjct: 849 FKCCQVDPQKRP 884
>19301
Length = 712
Score = 85.9 bits (211), Expect = 4e-17, Method: Compositional matrix adjust.
Identities = 52/153 (33%), Positives = 84/153 (54%), Gaps = 1/153 (0%)
Frame = +2
Query: 235 EDEWEVPRETLKLVERLGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPDAFLAEANLMKQ 294
+D+WE+P E++ +E LG+G G V++G +VAVK ++ D + +++
Sbjct: 281 QDDWEIPFESITDLEWLGSGAQGAVFLGKLCAE-EVAVKKVR------DIKETDIRNLRK 439
Query: 295 LQHQRLVRLYAVVTQEPIY-IITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMA 353
L H ++ V TQ P Y II EY G L + L+ G ++ +LD + QIA GM
Sbjct: 440 LNHPNIISFKGVCTQAPCYCIIMEYCPYGQLYEVLR--DGKEIPPALVLDWSKQIASGMN 613
Query: 354 FIEERNYIHRDLRAANILVSDTLSCKIADFGLA 386
++ IHRDL++ N+LV+ KI+DFG +
Sbjct: 614 YLHSHKIIHRDLKSPNVLVAKNDVVKISDFGTS 712
>13305
Length = 549
Score = 84.3 bits (207), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 37/89 (41%), Positives = 52/89 (58%)
Frame = +2
Query: 399 GAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYR 458
+ PI+W A E++ T+T +SDVWSFG++L EI T G PY ++ L+ GYR
Sbjct: 2 STRVPIRWMAVESLFNNTYTTQSDVWSFGVVLWEIFTLGGTPYSSTDTQQLFAFLKDGYR 181
Query: 459 MVRPDNCPEELYQLMRLCWKERPEDRPTF 487
+ RP C + Y +M CW E + RPTF
Sbjct: 182 LKRPKLCDQNTYAMMLQCWNENAQRRPTF 268
>13592
Length = 980
Score = 77.8 bits (190), Expect = 9e-15, Method: Compositional matrix adjust.
Identities = 60/252 (23%), Positives = 123/252 (48%), Gaps = 17/252 (6%)
Frame = +2
Query: 250 RLGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPDAFLAEANLMKQLQ------HQRLVRL 303
++G G+FG+V+ N ++ ++K+ ++ P A N+ ++L+ H+ LVR
Sbjct: 5 KIGQGRFGKVYTAVNNNTGELM--AMKEIAIQPGETRALKNVAEELKILEGIKHKNLVRY 178
Query: 304 YAV-VTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIH 362
Y + V +E + I E G+L ++ G+ +++ AQ+ G+A + + +H
Sbjct: 179 YGIEVHREELLIFMELCSEGTLESLVELTGGLPEALSR--RFTAQLLSGVAELHKHGIVH 352
Query: 363 RDLRAANI-LVSDTLSCKIADFGLARLIEDNE--------YTAREGAKFPIKWTAPEAIN 413
RD++ ANI LV + S K+ DFG A I+ + Y + P +T +
Sbjct: 353 RDIKTANIFLVDGSNSLKLGDFGSAVKIQAHTTVPGELQGYVGTQAYMAPEVFTKTNSDG 532
Query: 414 YGTFTIKSDVWSFGILLTEIVTHGRIPYPGM-TNPEVIQNLERGYRMVRPDNCPEELYQL 472
+G +D+WS G ++ E+ + G+ P+ +N +++ + G + P++ +E +
Sbjct: 533 HGRL---ADIWSVGCVVVEMAS-GKRPWAQFDSNFQIMFKVGMGEKPQAPESLSQEGHDF 700
Query: 473 MRLCWKERPEDR 484
+ C + P+ R
Sbjct: 701 IDHCLQHDPKQR 736
>18921
Length = 697
Score = 77.4 bits (189), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 51/196 (26%), Positives = 96/196 (48%), Gaps = 3/196 (1%)
Frame = +2
Query: 241 PRETLKLVERLGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPDA--FLAEANLMKQLQHQ 298
P + ++ +LG G +G V+ + +V ++KQ + D + E ++M+Q +
Sbjct: 23 PEDVFDILGKLGEGSYGSVFKSLHKETGQVL--AIKQVPVDTDLQEIIKEISIMQQCDSK 196
Query: 299 RLVRLY-AVVTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEE 357
+V+ Y + ++I+ EY GS+ D ++ + L ++ + +G+ ++
Sbjct: 197 YIVKYYGSYFKNTDLWIVMEYCGAGSVSDIMRLRNK-TLVEREIATILYYTLKGLXYLHS 373
Query: 358 RNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTF 417
R IHRD++A NIL+++ K+ADFG+A + D P W APE I +
Sbjct: 374 RRKIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTPY-WMAPEVIQEIGY 550
Query: 418 TIKSDVWSFGILLTEI 433
+D+WS GI E+
Sbjct: 551 DCVADIWSLGITALEM 598
>12721
Length = 821
Score = 77.4 bits (189), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 46/196 (23%), Positives = 94/196 (47%), Gaps = 2/196 (1%)
Frame = +1
Query: 241 PRETLKLVERLGAGQFGEVWMGYYNGHTKVAVKSLK-QGSMSPDAFLAEANLMKQLQHQR 299
PR L ++G G G V + ++AVK + + + E +M+ H
Sbjct: 82 PRTFLDDFMKIGEGSTGIVCIATSRDGRQMAVKKMDLRKQQRRELLFNEVVVMRDYHHPN 261
Query: 300 LVRLY-AVVTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEER 358
+V +Y + + + ++++ E+ME G+L D + + ++ ++ + + +AF+
Sbjct: 262 IVEMYNSYLVNDELWVVMEFMEGGALTDIV---TNNRMDEVQIATVCRACLKALAFLHAN 432
Query: 359 NYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFT 418
IHRD+++ +IL+S K+ DFG + + + P W APE I+ +
Sbjct: 433 GVIHRDIKSDSILLSHDGKVKLXDFGFCAQVTQDLQKRKSLVGTPY-WMAPEVISRLPYG 609
Query: 419 IKSDVWSFGILLTEIV 434
+ D+WS GI++ E++
Sbjct: 610 PEVDIWSLGIMVMEMI 657
>07833
Length = 1504
Score = 77.0 bits (188), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 60/220 (27%), Positives = 108/220 (49%), Gaps = 9/220 (4%)
Frame = -3
Query: 285 FLAEANLMKQLQHQRLVRLYAVVTQEP-IYIITEYMENGSLVDFLKTPSGIKLTINKLLD 343
F+ E ++ H ++ + A Q P + +I+++M GSL + L SGI + N+ L
Sbjct: 1478 FMEEFPRLRIFNHPNVLPVLACCNQPPNLVLISQFMPFGSLYNTLHGESGIVVDQNQSLR 1299
Query: 344 MAAQIAEGMAFIE--ERNYIHRDLRAANILVSDTLSCKI--ADFGLARLIEDNEYTAREG 399
A IA GM F+ E + L + ++++ + L+ +I AD+ + +G
Sbjct: 1298 FAMDIARGMEFLHSMEPTIPNFLLTSKHVMIDEDLTARINMADYCFS--------FHEKG 1143
Query: 400 AKFPIKWTAPEAINY---GTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEV-IQNLER 455
+ W APEA+ T +D+WSF IL+ E+ T +P+ +++ EV ++
Sbjct: 1142 KVYSPAWMAPEALQRRPDDINTRAADMWSFAILMWELETR-EVPFAELSSMEVGMKVALE 966
Query: 456 GYRMVRPDNCPEELYQLMRLCWKERPEDRPTFDYLRSVLE 495
G R+ P + +L+++C E P RP FD + +LE
Sbjct: 965 GLRISIPPGISLHMSRLIKICMNEEPGKRPRFDMIIPILE 846
>01060
Length = 1800
Score = 76.3 bits (186), Expect = 3e-14, Method: Compositional matrix adjust.
Identities = 58/230 (25%), Positives = 112/230 (48%), Gaps = 6/230 (2%)
Frame = +1
Query: 237 EWEVPRETLKLVERLGAGQFGEVWMGYYNGH-TKVAVKSLK-QGSMS--PDAFLAEANLM 292
++E L +++G G +G V+ + K+A+K ++ +GS P + + E ++
Sbjct: 55 DFETALSDLTDFQKIGEGTYGVVYKCRHRATGRKLAMKKIRLRGSEDGVPSSAIREIAML 234
Query: 293 KQLQHQRLVRLYAVVTQ-EPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEG 351
++L+H +V L V+ + E ++++ E++ + K P G+ L + QI G
Sbjct: 235 RELRHTNIVCLEDVIMEDERLFLVFEFLSMDLKMYIDKFPEGVVLDRRLVKSYVFQIVTG 414
Query: 352 MAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEA 411
+ F +R +HRDL+ N+L++ T + KIADFG+AR A + + APE
Sbjct: 415 IXFCHQRRIVHRDLKPQNLLINHTGAIKIADFGMARTFA-LPVRAYTHEVVTLWYRAPEI 591
Query: 412 I-NYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMV 460
+ ++ DVWS G + +++ I P I L + +R++
Sbjct: 592 LMGASKYSTPVDVWSIGTIFADML----IRTPIFKGDSEIDQLFKIFRII 729
>29581
Length = 1278
Score = 75.1 bits (183), Expect = 6e-14, Method: Compositional matrix adjust.
Identities = 53/187 (28%), Positives = 98/187 (52%), Gaps = 10/187 (5%)
Frame = -2
Query: 275 LKQGSMSPDAFLAEANLMKQLQHQRLVRLYAVV---TQEPIYIITEYMEN--GSLVDFLK 329
L++ +SP + + L+HQ +V+L VV + + ++++ EY E SL+D +
Sbjct: 1244 LERDMVSPSVVCVRSTFLLNLRHQNIVQLQEVVVGKSLDSLFLVMEYCEQDLASLLDNMP 1065
Query: 330 TPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLI 389
P + +++ + Q+ +G+ ++ E IHRDL+ +N+L++D KIADFGLAR
Sbjct: 1064 AP----FSESQVKCIVLQLLKGLRYLHEAFIIHRDLKVSNLLMTDKGCVKIADFGLAR-- 903
Query: 390 EDNEYTAREGAKFP----IKWTAPEAI-NYGTFTIKSDVWSFGILLTEIVTHGRIPYPGM 444
Y + P + + APE + T + D+WS G +L E++ H + PG
Sbjct: 902 ---NYGKPQKPMTPKVVTLWYRAPELLFGSKTHSTAIDMWSAGCILGELLGHKPL-MPGR 735
Query: 445 TNPEVIQ 451
++ + I+
Sbjct: 734 SDLQQIE 714
>17253
Length = 483
Score = 72.8 bits (177), Expect = 3e-13, Method: Composition-based stats.
Identities = 45/153 (29%), Positives = 75/153 (49%), Gaps = 16/153 (10%)
Frame = -1
Query: 270 VAVKSLKQGSMSPDA--FLAEANLMKQL-QHQRLVRLYAVVT-QEPIYIITEYMENGSLV 325
VAVK+ + + + FL E ++M++L +H +V T +P I+ E+ +G L+
Sbjct: 459 VAVKTHNEAATDAEKSEFLRELSIMRKLPRHPNVVSFMGCCTMSDPALILMEFCCHGDLL 280
Query: 326 DFLK----------TPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDT 375
FL+ T + LT A +A GMA + +HRD+ A N+L+S+
Sbjct: 279 SFLRKRRPDRTVFLTSTANDLTARDFFSFALHVARGMAHVANNKIVHRDVAARNVLISER 100
Query: 376 LSCKIADFGLARLIEDNE--YTAREGAKFPIKW 406
CK++DFGL+R + D Y P++W
Sbjct: 99 NVCKVSDFGLSRRVGDQNDVYEIVSRRPLPLRW 1
>14126
Length = 1265
Score = 72.4 bits (176), Expect = 4e-13, Method: Compositional matrix adjust.
Identities = 56/202 (27%), Positives = 97/202 (48%), Gaps = 14/202 (6%)
Frame = +3
Query: 248 VERLGAGQFGEVWMG--YYNGHTKVAVKSLKQGSMS---PDAFLAEANLMKQLQ---HQR 299
V +G G +G V+ N VA+K ++ + P + E +++KQL+ H
Sbjct: 204 VAVIGNGAYGTVYKARDLRNQGEFVAMKRIRLNNTEEGMPMMAIREISMLKQLEQYEHPN 383
Query: 300 LVRLYAV----VTQEPIYI--ITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMA 353
+VRL V +T I + + EY+E+ K PS L +++ D+ Q+ G+
Sbjct: 384 VVRLLDVSHNTITDREIRLNLVFEYIEHDLATYLAKCPSP-GLGPDRIKDLMLQLLNGVD 560
Query: 354 FIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAIN 413
F+ +HRDL+ N+L+S K+ADFGLAR+ + + A + + +PE +
Sbjct: 561 FLHSNRIVHRDLKPQNLLISKDGRLKLADFGLARIY--SFHMALTTVVVTLWYRSPEVLM 734
Query: 414 YGTFTIKSDVWSFGILLTEIVT 435
+ D+WS G + E+ T
Sbjct: 735 QAEYGTSVDIWSCGCIFAELFT 800
>01707
Length = 757
Score = 72.0 bits (175), Expect = 6e-13, Method: Compositional matrix adjust.
Identities = 56/212 (26%), Positives = 108/212 (50%), Gaps = 8/212 (3%)
Frame = +1
Query: 243 ETLKLVERLGAGQFGEVWMGYYNGHTK-VAVKSLKQGSMSP---DAFLAEANLMKQLQHQ 298
E + + ++G G +G V+ ++ VA+K + P + E ++KQL+H
Sbjct: 64 EKYEKIGKIGEGSYGVVFKCRNKETSQLVAIKKFVESEDDPLIKKIAMREIRMLKQLKHP 243
Query: 299 RLVRLYAVVTQEP-IYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEE 357
LVRL V ++ ++++ +Y+++ L + + P G+ + K + Q + F +
Sbjct: 244 NLVRLIEVFRRKKRLHLVFDYVDHTLLNELDRYPRGLPEPMVK--RIIYQTLLAVNFCHQ 417
Query: 358 RNYIHRDLRAANILVSDTLSCKIADFGLARLIE--DNEYTAREGAKFPIKWTAPEAINYG 415
N IHRD++ NIL++ K+ DFG AR++ +EYT ++ + APE +
Sbjct: 418 YNTIHRDVKPENILITRQGQVKLCDFGFARILTGPGDEYTDYVATRW---YRAPELLVGD 588
Query: 416 T-FTIKSDVWSFGILLTEIVTHGRIPYPGMTN 446
T + DVW+ G + E++T G+ +PG ++
Sbjct: 589 TQYGPPVDVWAIGCVFAELLT-GQALWPGRSD 681
>01756
Length = 1858
Score = 68.6 bits (166), Expect = 6e-12, Method: Compositional matrix adjust.
Identities = 61/232 (26%), Positives = 102/232 (43%), Gaps = 33/232 (14%)
Frame = -3
Query: 241 PRETLKL-----------VERLGAGQFGEVWMGYYN------GHTKVAVKSLKQGSMSPD 283
P ETLK + ++G G FGEV+ KV + + K+G P
Sbjct: 1781 PYETLKFPFCDEDAKYEKLAKIGQGTFGEVFKARCKKTKQVVAMKKVLMDNEKEGF--PI 1608
Query: 284 AFLAEANLMKQLQHQRLVRLYAVVTQEP---------IYIITEYMENGSLVDFLKTPSGI 334
L E +++ L H+ +V L + + + Y++ E+ E+ L L S +
Sbjct: 1607 TALREIKILQLLNHENVVDLIEICSTKATSANRYKSMFYLVFEFCEH-DLAGLLSNMSVV 1431
Query: 335 KLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLAR-----LI 389
+ ++ ++ Q+ G+ +I +HRD++AANIL++ K+ADFGLAR L
Sbjct: 1430 -FNLPEIKEVMKQLMNGLYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLR 1254
Query: 390 EDNEYTAREGAKFPIKWTAPEAINYG--TFTIKSDVWSFGILLTEIVTHGRI 439
+ N YT R W P + G ++ D W G ++ E+ T I
Sbjct: 1253 QPNRYTNR----VVTLWYRPPELLLGDRNYSTAIDQWGAGCIMAEMWTRNPI 1110
>00300
Length = 2318
Score = 68.2 bits (165), Expect = 8e-12, Method: Compositional matrix adjust.
Identities = 59/263 (22%), Positives = 117/263 (44%), Gaps = 13/263 (4%)
Frame = -1
Query: 250 RLGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPD------AFLAEANLMKQLQHQRLVRL 303
++G GQFG+V+ + + +LK+ P+ E + + +QH+ LV+
Sbjct: 1637 KIGEGQFGKVYTAV--NMSTGELMALKEMKFQPNDLQQLREMCDEIKIFEGIQHENLVKY 1464
Query: 304 YAV-VTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIH 362
Y V V ++ + + EY + G++ + K + L + +I + + E + +H
Sbjct: 1463 YGVEVHKDEMLMFMEYCDTGTIEEAAK----MGLPEYLIRRYTREIVLAVNHLHENSIVH 1296
Query: 363 RDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKF--PIKWTAPEAI---NYGTF 417
RD++ ANI ++ K+ DFG + ++ + E + APE + G +
Sbjct: 1295 RDIKGANIFLTSNGHVKLGDFGCSVKLKSHTTMPGEFHNLVGTTAYMAPEVFTQNDQGGY 1116
Query: 418 TIKSDVWSFGILLTEIVTHGRIPYPGMTNP-EVIQNLERGYRMVRPDNCPEELYQLMRLC 476
+D+WS G ++ E+ T G+ P+ + N +++ + G++ PD+ E + L
Sbjct: 1115 GRAADIWSLGCVVIEMAT-GKRPWHDLDNNYQIMYKVGIGHKPAVPDSLSVEGKHFLDLI 939
Query: 477 WKERPEDRPTFDYLRSVLEDFFT 499
P R L L+ FT
Sbjct: 938 MCHDPAQRALASQL---LDHTFT 879
>00715
Length = 1788
Score = 67.0 bits (162), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 49/172 (28%), Positives = 82/172 (47%), Gaps = 27/172 (15%)
Frame = +1
Query: 342 LDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLI------------ 389
L +A Q+A G+ ++ N +H DL+ AN L++ L +IADFG +
Sbjct: 247 LSLALQMARGLHYLHSINIVHLDLKPANCLLTRDLKLRIADFGCCHQLTPTGLDMGEREG 426
Query: 390 ----EDNEYTAREGA-----KFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIP 440
+ E T +GA + + APE + +++SDV+S GI L ++ T + P
Sbjct: 427 GMAGNELELTPVQGAWKNELAGTLAYRAPELLKGLQPSVRSDVYSLGITLWQMCTR-QGP 603
Query: 441 YPGMTNPEVI-QNLERGYRMVRPDNCPEELYQLM-----RLCWKERPEDRPT 486
Y G+ V+ Q + + R P + ++ +++M CW R EDRPT
Sbjct: 604 YEGVPAHAVVYQVVSKDLRPCPPPSTEDDPFEVMFRDLYTQCWARRVEDRPT 759
>01966
Length = 1735
Score = 65.1 bits (157), Expect = 6e-11, Method: Compositional matrix adjust.
Identities = 38/123 (30%), Positives = 71/123 (57%), Gaps = 4/123 (3%)
Frame = -1
Query: 269 KVAVKSLK-QGSMS--PDAFLAEANLMKQLQHQRLVRLYAVVTQ-EPIYIITEYMENGSL 324
K+A+K ++ +GS P + + E ++++L+H +V L V+ + E ++++ E++
Sbjct: 1630 KLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTNIVCLEDVIMEDERLFLVFEFLSMDLK 1451
Query: 325 VDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFG 384
+ K P G+ L + QI G+ F +R +HRDL+ N+L++ T + KIADFG
Sbjct: 1450 MYIDKFPEGVVLDRRLVKSYVFQIVTGINFCHQRRIVHRDLKPQNLLINHTGAIKIADFG 1271
Query: 385 LAR 387
+AR
Sbjct: 1270 MAR 1262
>14420
Length = 528
Score = 64.7 bits (156), Expect = 9e-11, Method: Compositional matrix adjust.
Identities = 39/162 (24%), Positives = 80/162 (49%), Gaps = 3/162 (1%)
Frame = +2
Query: 283 DAFLAEANLMKQLQHQRLVR-LYAVVTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKL 341
+ + E +M++ Q+ +V L + + E ++++ E++ GSL D + + ++
Sbjct: 35 ELIINEILVMRENQNPNIVNYLDSYLVGEELWVVMEFLAGGSLTDVVTETC---MDEGQI 205
Query: 342 LDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLI--EDNEYTAREG 399
+ + + + F+ E IHRD+++ NIL+ S K+ DFG + E ++ + G
Sbjct: 206 AAVCRECLQALEFLHENQVIHRDIKSDNILLGMDGSVKLTDFGFCAQLSPEQSKRSTMVG 385
Query: 400 AKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPY 441
+ W APE + + D+WS G++ E++ G PY
Sbjct: 386 TPY---WMAPEVVTRKQYGPTVDIWSLGVMCIEMI-EGEPPY 499
>27546
Length = 426
Score = 63.9 bits (154), Expect = 1e-10, Method: Composition-based stats.
Identities = 33/108 (30%), Positives = 59/108 (54%), Gaps = 1/108 (0%)
Frame = -1
Query: 285 FLAEANLMKQLQHQRLVRLYAVVTQEP-IYIITEYMENGSLVDFLKTPSGIKLTINKLLD 343
F E ++ +L H ++++++++ + P I+I Y E G ++ +K I K+
Sbjct: 339 FPRELEILTRLDHPNIIQIHSILQRGPKIFIFMRYAEKGDMLSHIKKTGPIDEAQTKVWF 160
Query: 344 MAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIED 391
Q+A+ + ++ + HRDL+ NIL+S L+ KIADFG AR D
Sbjct: 159 F--QMAKALQYLHSHDIAHRDLKCENILLSKRLNVKIADFGFARYCRD 22
>18484
Length = 635
Score = 63.2 bits (152), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 39/140 (27%), Positives = 70/140 (50%)
Frame = +1
Query: 345 AAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPI 404
AA+IA G+ F+ ++ I+RDL+ N+++ KIADFG+ + + T R P
Sbjct: 61 AAEIAVGLFFLHDQGIIYRDLKLDNVMLDSEGHIKIADFGMCKEGMTGDATTRTFCGTP- 237
Query: 405 KWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDN 464
+ APE + Y ++ D W++G+LL E++ G+ P+ G E+ ++ + + P
Sbjct: 238 DYIAPEIVLYQPYSKSVDWWAYGVLLFEMLA-GQPPFDGEDEDELFSSI-TDHNVSYPKA 411
Query: 465 CPEELYQLMRLCWKERPEDR 484
E L + + P R
Sbjct: 412 MSREAVSLCKGLLMKNPTKR 471
>12672
Length = 773
Score = 63.2 bits (152), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 43/166 (25%), Positives = 72/166 (43%), Gaps = 17/166 (10%)
Frame = +3
Query: 349 AEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPI---K 405
A G+ ++ + ++HRD++ ANIL+ + K+ DF E + A I
Sbjct: 21 ASGIQYLNDNGHVHRDIKTANILLDSEYTAKVGDFATVVSAPSGEGKTVQNASVVIGTAA 200
Query: 406 WTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIP--------------YPGMTNPEVIQ 451
+ APEAI++ T K D +SFG++L E++T G + + PE I
Sbjct: 201 YLAPEAIHFDVST-KLDSYSFGVVLLEVIT-GLVAQDYSREERTLSSHIMENVEEPEEIH 374
Query: 452 NLERGYRMVRPDNCPEELYQLMRLCWKERPEDRPTFDYLRSVLEDF 497
+ PD ++LY + C + RP +R LE+
Sbjct: 375 DFVDQSAGTWPDGAVDKLYDISMRCLNLSKKQRPNVKDIRPELEEL 512
>25550
Length = 941
Score = 60.5 bits (145), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 28/63 (44%), Positives = 39/63 (61%)
Frame = +3
Query: 439 IPYPGMTNPEVIQNLERGYRMVRPDNCPEELYQLMRLCWKERPEDRPTFDYLRSVLEDFF 498
+ YPG+ EV LERGYRM RP P ++Y LM CW+ P++RPTF + +LE+ F
Sbjct: 36 VXYPGVDLTEVYHLLERGYRMERPQGTPADVYILMLKCWQWDPKERPTFKEIHYLLENMF 215
Query: 499 TAT 501
+
Sbjct: 216 EKS 224
>04591
Length = 1117
Score = 60.5 bits (145), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 42/166 (25%), Positives = 82/166 (49%), Gaps = 14/166 (8%)
Frame = -2
Query: 282 PDAFLAEANLMKQLQHQRLVRLYAVVTQEP---------IYIITEYMEN--GSLVDFLKT 330
P L E +++QL+H+ +V+L + + Y+I EY + L++ L+
Sbjct: 1089 PITALREIKILQQLEHENVVQLQEICHTQAGPYNRYKSTFYLIFEYCDYDLAGLLNNLR- 913
Query: 331 PSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLAR-LI 389
+K ++ ++ +Q+ G+ +I + +HRD++AANIL++ K+ADFGL+R +
Sbjct: 912 ---VKFSLADKKNLMSQLLNGLFYIHTKQILHRDIKAANILLTRDGVLKLADFGLSRPWV 742
Query: 390 EDNEYTAREGAKFPIKWTAPEAINYG--TFTIKSDVWSFGILLTEI 433
+ T R W P + G + + D+W G ++ E+
Sbjct: 741 KSKRLTNR----VVTLWYRPPELLLGEREYGPEIDMWGVGCIMAEM 616
>07836
Length = 1478
Score = 59.3 bits (142), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 61/220 (27%), Positives = 105/220 (47%), Gaps = 45/220 (20%)
Frame = -1
Query: 312 IYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNY--------IHR 363
+++IT+Y ENGSL D+L + L +++L +A G+A + + HR
Sbjct: 1328 LFLITDYHENGSLHDYLLSRV---LDSSEMLALAHSAICGLAHLHIEIFGTRGKPAIAHR 1158
Query: 364 DLRAANILVSDTLSCKIADFGLA-RLI-EDNEYTA----REGAKFPIKWTAPEAI----- 412
D+++ NILV +C IAD GLA R I E NE R+G K ++ APE +
Sbjct: 1157 DIKSKNILVKKNGTCCIADLGLAVRYISESNEVDVAPNPRQGTK---RYMAPEVLEMLLN 987
Query: 413 --NYGTFTIKSDVWSFGILLTEI----VTHG-----RIPY-------PGMTNPEVIQNLE 454
N+ F ++D+++FG+++ EI V G ++P+ P + ++ +++
Sbjct: 986 VKNFDAFK-QADMYAFGLVMWEIARCCVIGGVAEEYQVPFYNCLPHDPSFEDVRLVVSVD 810
Query: 455 RGYRMVRPDN--------CPEELYQLMRLCWKERPEDRPT 486
+ VRPD + + ++M CW P R T
Sbjct: 809 K----VRPDIPLRWQEDPIMKVMVKVMCECWSGNPAARLT 702
>31885
Length = 529
Score = 57.0 bits (136), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 41/169 (24%), Positives = 76/169 (44%), Gaps = 8/169 (4%)
Frame = -2
Query: 289 ANLMKQLQHQRLVRL-YAVVTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQ 347
+++ +L H LV L YA +E ++++ + G L ++ + K Q
Sbjct: 519 VDMLTRLDHPFLVNLWYAFQDEEDLFMVVDLFLGGDLRYHMQQEVSFREDCVKF--YLCQ 346
Query: 348 IAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWT 407
+A + ++ + +HRD++ NIL+ + C + DF +A +ED+E P +
Sbjct: 345 LALVLDYLRSQKIVHRDIKPDNILLDEQGHCHVTDFNIATQLEDDELATSTSGTRP--YM 172
Query: 408 APEAINYGT-------FTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEV 449
APE YG + D WS G+ L E++ R P+ +N +
Sbjct: 171 APEV--YGVAINERRGYGFPVDWWSLGVSLFELLKKRR-PFSVHSNTSL 34
>17975
Length = 449
Score = 56.6 bits (135), Expect = 3e-08, Method: Composition-based stats.
Identities = 38/124 (30%), Positives = 65/124 (52%), Gaps = 6/124 (4%)
Frame = +3
Query: 269 KVAVKSL---KQGSMSPDAFLAEANLMKQLQHQRLVRLYAVV-TQEPIYIITEYMENGSL 324
KVAVK + K +S E MK +QH +VRLY V+ TQ +Y+I E + G +
Sbjct: 48 KVAVKVIDKTKLDEVSRSHLFQEVRCMKLVQHPNVVRLYEVIDTQTKLYLILELGDGGDM 227
Query: 325 VDF-LKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLS-CKIAD 382
D+ ++ G++ + K QI E +++ + + +HRDL+ N++ + K+ D
Sbjct: 228 YDYIMRHSGGLEEKLAK--RYFRQIVEAISYCHKLHVVHRDLKPENVVFFEKPGLVKLTD 401
Query: 383 FGLA 386
FG +
Sbjct: 402 FGFS 413
>13066
Length = 551
Score = 56.2 bits (134), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 42/172 (24%), Positives = 80/172 (46%), Gaps = 8/172 (4%)
Frame = +3
Query: 264 YNGHTKVAVKSLKQGSMSPDA----FLAEANLMKQLQHQRLVRLYAVVTQEPI-YIITEY 318
Y + K+A K + + D F E +L+ +L H ++++++++ + P +I +
Sbjct: 42 YGRNIKLACKIIDKEKAPVDFVEKFFPRELDLLTKLDHPYIIQIHSILQRXPKNFIFMRF 221
Query: 319 MENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSC 378
E G L+ +++ +K K+ Q+ + ++ + HRDL+ NIL+S +
Sbjct: 222 AERGDLLTYIQEVGFVKEKQAKI--WFYQMTTALNYLHSYDVAHRDLKCENILLSSHFNV 395
Query: 379 KIADFGL--ARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIK-SDVWSFG 427
K+ADFG A + E E + APE + + K +D WS G
Sbjct: 396 KLADFGFACACITESGEKYMSRTYCGSAAYAAPEIVYGAPYAPKVADAWSLG 551
>19094
Length = 898
Score = 55.1 bits (131), Expect = 7e-08, Method: Compositional matrix adjust.
Identities = 29/84 (34%), Positives = 45/84 (53%)
Frame = +1
Query: 350 EGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAP 409
+G+ ++ R IHRD++A NIL+++ K+ADFG+A + D P W AP
Sbjct: 91 KGL*YLHSRRKIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTP-YWMAP 267
Query: 410 EAINYGTFTIKSDVWSFGILLTEI 433
E I + +D+WS GI E+
Sbjct: 268 EVIQEIGYDCVADIWSLGITALEM 339
>09606
Length = 1300
Score = 54.7 bits (130), Expect = 9e-08, Method: Compositional matrix adjust.
Identities = 49/225 (21%), Positives = 88/225 (39%), Gaps = 22/225 (9%)
Frame = -3
Query: 243 ETLKLVERLGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPDAFLAEANLMKQLQHQRLVR 302
E L E LG G+ ++ G G + P+ + + H +V+
Sbjct: 1115 ENFVLYEELGKGEHSIIYKGRRKGTINFVAIHCIEKCKRPEV-TNTVRMTHDISHPNVVQ 939
Query: 303 LYA-VVTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYI 361
+ T ++++ E GSL D L + T + D + G+ +I +
Sbjct: 938 FHEWYETSNHLWLVVELCTGGSLADILAQDHHLPET--SIRDFGIHLVTGLHYIHSLGIL 765
Query: 362 HRDLRAANILVSDTLSCKIADFGLARLIEDNEYT-----AREGAKFPIK----------- 405
DLR + +L+ + K ADFGL+++ +N A G ++ I+
Sbjct: 764 FHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQWNIQSAEEMMKQVPT 585
Query: 406 -----WTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMT 445
+ APE +I SD+W+ G + E+ + G P+ G T
Sbjct: 584 SGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFS-GHPPFLGET 453
>03240
Length = 1683
Score = 53.9 bits (128), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 63/284 (22%), Positives = 120/284 (42%), Gaps = 55/284 (19%)
Frame = -3
Query: 248 VERLGAGQFGEVWMGYYNGHTKV-AVKSLKQGSM----SPDAFLAEANLMKQLQHQRLVR 302
++ LG G FGEV + N + A+K+L++ + AE +++ + ++ +V+
Sbjct: 1276 IKTLGVGAFGEVSLCRKNDTGMLYAMKTLRKSDVLKRNQVAHVKAERDILAEADNEWVVK 1097
Query: 303 LY-AVVTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYI 361
LY + +Y + +Y+ G L+ L + + + A++ + + + +I
Sbjct: 1096 LYYSFQDHNYLYFVMDYVPGGDLMGLLIRMEILDEPLARFY--VAELVQAIESVHRMGFI 923
Query: 362 HRDLRAANILVSDTLSCKIADFGLA---RLIEDNEYTAREGAKF---------------- 402
HRD++ NIL+ K+ DFGL R +++Y R+G
Sbjct: 922 HRDIKPDNILIDRNGHIKLTDFGLCTGFRWTHNSKYYQRDGTHARQDSMEVKCQLDEQCQ 743
Query: 403 -----PIK-------------------WTAPEAIN-YGTFTIKSDVWSFGILLTEIVTHG 437
P++ + APE ++ G +T D WS G++L E++ G
Sbjct: 742 CEILKPLERRRKREQRCLAHSLVGTPNYIAPEVLSRLGGYTSVCDWWSVGVILFEMLV-G 566
Query: 438 RIPY----PGMTNPEVIQNLERGYRMVRPDNCPEELYQL-MRLC 476
P+ P T +VI N + ++ R N + L +RLC
Sbjct: 565 HPPFYANTPAETQYKVI-NWKDMLKIPRESNLSQPAKDLILRLC 437
>21079
Length = 878
Score = 50.8 bits (120), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 38/137 (27%), Positives = 68/137 (49%), Gaps = 4/137 (2%)
Frame = +1
Query: 297 HQRLVRLY-AVVTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFI 355
H +L+ L+ A + ++ E++ G L + + + LT + QI G+ ++
Sbjct: 1 HPKLLMLWDAFEAPRTMVLVMEFVGAGELFERVIRDDFV-LTERDCVHFVRQICSGVGYM 177
Query: 356 EERNYIHRDLRAANIL-VSDTLS-CKIADFGLARLIE-DNEYTAREGAKFPIKWTAPEAI 412
++ +H DL+ N+L VSD + KI DFGLAR + + G ++ APE +
Sbjct: 178 HTQSILHLDLKPENVLCVSDNSNQIKIIDFGLARFYKPGDSLQVLFGTP---EFIAPEVV 348
Query: 413 NYGTFTIKSDVWSFGIL 429
NY +D+WS G++
Sbjct: 349 NYDEINFTTDMWSIGVI 399
>30755
Length = 1137
Score = 50.8 bits (120), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 37/142 (26%), Positives = 69/142 (48%), Gaps = 2/142 (1%)
Frame = +2
Query: 345 AAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEY--TAREGAKF 402
A+I + ++ + I+RDL+ N+L+ K+ADFGL + ED Y T +
Sbjct: 50 GAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCK--EDITYGRTTKTFCGT 223
Query: 403 PIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRP 462
P ++ APE ++ + D W G+++ E++ GR+P+ + +V+ L + P
Sbjct: 224 P-EYLAPEVLDDNDYGRAVDWWGTGVVMYEMIC-GRLPFYNRDH-DVLFTLILVEDVKFP 394
Query: 463 DNCPEELYQLMRLCWKERPEDR 484
N +E L+ + P +R
Sbjct: 395 RNITDEAKSLLSGLLAKDPRNR 460
>15910
Length = 1361
Score = 49.7 bits (117), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 34/114 (29%), Positives = 57/114 (50%), Gaps = 3/114 (2%)
Frame = +2
Query: 346 AQIAEGMAFIEERNYIHRDLRAANIL---VSDTLSCKIADFGLARLIEDNEYTAREGAKF 402
+ I G+ +I +HRDL+ N+L ++D K+ADFGL+R+IE E
Sbjct: 485 SDILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLADFGLSRIIEP-EVQMSTVCGT 661
Query: 403 PIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERG 456
P + APE + +T D+WS G+ + I+ G P+ E+ + + +G
Sbjct: 662 P-GYCAPEVLKGDKYTPSVDMWSVGV-IAYILLCGYEPFFAENEFEMYRKIIKG 817
>04138
Length = 800
Score = 49.3 bits (116), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 32/97 (32%), Positives = 47/97 (48%), Gaps = 7/97 (7%)
Frame = +1
Query: 350 EGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLAR-----LIEDNEYTAREGAKFPI 404
E + +I +HRD++AANIL++ K+ADFGLAR L + N YT R
Sbjct: 46 ERLYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNR----VVT 213
Query: 405 KWTAPEAINYG--TFTIKSDVWSFGILLTEIVTHGRI 439
W P + G ++ D W G ++ E+ T I
Sbjct: 214 LWYRPPELLLGDRNYSTAIDQWGAGCIMAEMWTRNPI 324
>13212
Length = 1067
Score = 49.3 bits (116), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 28/93 (30%), Positives = 48/93 (51%), Gaps = 7/93 (7%)
Frame = -1
Query: 347 QIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKF--PI 404
++ + F+ + IHRD++A N+L++ K+ADFG++ N T ++ F
Sbjct: 956 EMCMALDFLHRHHVIHRDIKAGNVLLTIDGEVKLADFGVSA---KNTQTQQKRDTFIGTP 786
Query: 405 KWTAPEAINYGT-----FTIKSDVWSFGILLTE 432
W APE + T + K+D+WS G+ L E
Sbjct: 785 YWMAPEVVLCETLKDTPYDFKADIWSLGVTLIE 687
>26711
Length = 405
Score = 47.4 bits (111), Expect = 2e-05, Method: Composition-based stats.
Identities = 33/111 (29%), Positives = 58/111 (52%), Gaps = 3/111 (2%)
Frame = -2
Query: 347 QIAEGMAFIEERNYIHRDLRAANILVS-DTL-SCKIADFGLAR-LIEDNEYTAREGAKFP 403
Q+ + + + + +H DL+ +N+L+S D L S ++ DFGLAR L E G
Sbjct: 392 QVLDILQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARKLYPPQETFLNHGTP-- 219
Query: 404 IKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLE 454
+T+PEA++ + SDVW G+ L I+ G+ P+ + E ++ +
Sbjct: 218 -GFTSPEALDVKPISTASDVWGVGV-LAYILLSGQSPFQADSATESLKKTQ 72
>35671
Length = 567
Score = 46.6 bits (109), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 18/47 (38%), Positives = 31/47 (65%)
Frame = -3
Query: 454 ERGYRMVRPDNCPEELYQLMRLCWKERPEDRPTFDYLRSVLEDFFTA 500
++G R+ +P +C +E Y++M CW E E+RPTF L V+E+ + +
Sbjct: 565 QKGNRLAKPISCTDEAYKVMLQCWTESREERPTFKKLVPVMENLYRS 425
>01392
Length = 1806
Score = 45.4 bits (106), Expect = 5e-05, Method: Compositional matrix adjust.
Identities = 34/109 (31%), Positives = 53/109 (48%), Gaps = 12/109 (11%)
Frame = -1
Query: 347 QIAEGMAFIEERNYIHRDLRAANIL---VSDTLSCKIADFGLARLIE-DNEYTAREGAKF 402
IA + F+ + HRDL+ NIL + D + KI DF LA I D + T
Sbjct: 1767 HIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGISCDGDGTKTPELLT 1588
Query: 403 PI---KWTAPEAINY-----GTFTIKSDVWSFGILLTEIVTHGRIPYPG 443
P+ ++ APE ++ ++ + D+WS GI+L I+ G P+ G
Sbjct: 1587 PVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILY-IMLCGYPPFYG 1444
>19761
Length = 473
Score = 45.1 bits (105), Expect = 7e-05, Method: Compositional matrix adjust.
Identities = 32/127 (25%), Positives = 61/127 (48%), Gaps = 4/127 (3%)
Frame = -3
Query: 347 QIAEGMAFIEERN--YIHRDLRAANILVSDTLSCKIADFGLARLIED--NEYTAREGAKF 402
Q A + ++ +HRDL+ NI V++ ++ D GLAR + + T++ G
Sbjct: 399 QTASALNYMHTHTPVILHRDLKPQNIYVTEKGDVRLGDLGLARKLTGPADFATSQVGT-- 226
Query: 403 PIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRP 462
I + +PE ++ + KSD+WS G + +I G+ M ++ + G ++ P
Sbjct: 225 -IMYLSPEILSQQPYNSKSDIWSLGCVFYDIT--GKKGSDEMGVMFLLVQVMGGRKLPLP 55
Query: 463 DNCPEEL 469
D+ +E
Sbjct: 54 DHYSQEF 34
>16708
Length = 1397
Score = 44.7 bits (104), Expect = 8e-05, Method: Compositional matrix adjust.
Identities = 35/151 (23%), Positives = 66/151 (43%), Gaps = 7/151 (4%)
Frame = -1
Query: 245 LKLVERLGAGQFGEVWMG-YYNGHTKVAVKSLKQGSMSPDAFLAEANLMKQLQHQRLVRL 303
+ +++ LG G FG+V+ + H K A+K+ S D A + ++
Sbjct: 1397 VAILQVLGKGVFGKVYEARLLSTHEKAALKTSILCHHSLDEVEALGRIEGGFYLAQMFGA 1218
Query: 304 YAVVTQEP-IYIITEYMENGSLVDFLKTPSGIKLTIN-----KLLDMAAQIAEGMAFIEE 357
+ P + I+ + E G L + ++ I + +A Q + I E
Sbjct: 1217 WVTCLPFPKMNILLHFYEMGPLCNVYAHYKNKEMPIRWSNPAMVCCIAGQXVCALEHIHE 1038
Query: 358 RNYIHRDLRAANILVSDTLSCKIADFGLARL 388
+H D++A N+LV +CK+ D+G+A+L
Sbjct: 1037 LGVVHMDVKADNVLVDAHGNCKLTDYGIAQL 945
>37602
Length = 804
Score = 44.3 bits (103), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 22/79 (27%), Positives = 43/79 (54%)
Frame = -1
Query: 305 AVVTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRD 364
+ + +E ++I EY GS+ D LT ++ + + +G+ ++ R +HRD
Sbjct: 315 SYLRREKLWIAMEYCGGGSMQDIYHVTG--PLTEPQIAFVCRETLKGLHYLHRRGKMHRD 142
Query: 365 LRAANILVSDTLSCKIADF 383
++ ANIL+++ K+ADF
Sbjct: 141 IKGANILLTEEGDVKLADF 85
>26560
Length = 398
Score = 43.9 bits (102), Expect = 1e-04, Method: Composition-based stats.
Identities = 29/98 (29%), Positives = 51/98 (52%), Gaps = 1/98 (1%)
Frame = -1
Query: 345 AAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPI 404
AA++ G+ + R ++RDL+ ANIL+ + +I+D GLA A G
Sbjct: 338 AAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGLACDFSKKRPHASVGTH--- 168
Query: 405 KWTAPEAINYG-TFTIKSDVWSFGILLTEIVTHGRIPY 441
+ APE + G ++ +D +SFG +L +++ G P+
Sbjct: 167 GYMAPEVLMKGQSYDSSADWFSFGCMLYKLLK-GHSPF 57
>27405
Length = 532
Score = 42.4 bits (98), Expect = 5e-04, Method: Compositional matrix adjust.
Identities = 35/121 (28%), Positives = 55/121 (45%)
Frame = -3
Query: 304 YAVVTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHR 363
YA T E + I + M G L L + G+ T ++ AA++ G+ + R ++R
Sbjct: 353 YAFQTPEKLCFILDLMNGGDLHYHL-SQHGV-FTEKEVRFYAAEVMLGLEHMHSRFVVYR 180
Query: 364 DLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDV 423
DL+ ANIL+ + +I+D GLA + A G + APE + G S
Sbjct: 179 DLKPANILLDENGHVRISDLGLACDFSKKKPHASVGTH---GYMAPEVLMKGQAYDSSAD 9
Query: 424 W 424
W
Sbjct: 8 W 6
>11185
Length = 473
Score = 42.0 bits (97), Expect = 6e-04, Method: Compositional matrix adjust.
Identities = 31/133 (23%), Positives = 56/133 (42%), Gaps = 21/133 (15%)
Frame = +1
Query: 343 DMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNE-----YTAR 397
D + G+ +I + DLR + +L+ + K ADFGL+++ +N A
Sbjct: 13 DFGIHLVTGLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAE 192
Query: 398 EGAKFPIK----------------WTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPY 441
G ++ I+ + APE +I SD+W+ G + E+ + R+
Sbjct: 193 AGDQWNIQSAEEMMKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSGSRL-- 366
Query: 442 PGMTNPEVIQNLE 454
+PE + LE
Sbjct: 367 SAKPSPEFLNLLE 405
>21433
Length = 590
Score = 41.6 bits (96), Expect = 7e-04, Method: Compositional matrix adjust.
Identities = 25/89 (28%), Positives = 41/89 (46%)
Frame = +2
Query: 347 QIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKW 406
Q++ + + R IHRD++ N+L+ KIADFG + + T G + +
Sbjct: 191 QLSSALEYCHYRKVIHRDIKPENLLLGLKGDLKIADFGWSVHAPSSRRTTMCGT---LDY 361
Query: 407 TAPEAINYGTFTIKSDVWSFGILLTEIVT 435
PE + T D+WS G+L E +
Sbjct: 362 LPPEMVEGKTHDENVDLWSLGVLCYEFLV 448
>12786
Length = 460
Score = 40.4 bits (93), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 30/108 (27%), Positives = 52/108 (48%), Gaps = 22/108 (20%)
Frame = -3
Query: 361 IHRDLRAAN-ILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPI-KWTAPEAINYGT-- 416
IH DL+ AN +LV+ L K+ DFG+A ++ ++ + + ++ + +PEAI
Sbjct: 344 IHSDLKPANFMLVAGNL--KLIDFGIANTLQQDKTSVLKDSRVGTPSYMSPEAIMAACDD 171
Query: 417 ------------------FTIKSDVWSFGILLTEIVTHGRIPYPGMTN 446
++SDVWS G +L +V +GR P+ + N
Sbjct: 170 SADDSMEEDGHRTKPKYKVGVRSDVWSLGCILYNMV-YGRTPFQHIKN 30
>18481
Length = 437
Score = 40.0 bits (92), Expect = 0.002, Method: Composition-based stats.
Identities = 20/64 (31%), Positives = 36/64 (56%), Gaps = 3/64 (4%)
Frame = -1
Query: 335 KLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCK---IADFGLARLIED 391
+ T+ +L ++ Q+ + FI ++ +IHRDL+ N L+ C I DFGL++ +D
Sbjct: 209 RFTLKTILMVSDQLLSRLEFIHQKCFIHRDLKPDNFLMGLGRHCHRLYIIDFGLSKRYKD 30
Query: 392 NEYT 395
+ T
Sbjct: 29 TQGT 18
>28638
Length = 1458
Score = 40.0 bits (92), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 31/111 (27%), Positives = 55/111 (49%), Gaps = 4/111 (3%)
Frame = -1
Query: 329 KTPSGIKLTINKLLDMAAQIAEGMAFIE--ERNYIHRDLRAANILVSD--TLSCKIADFG 384
+T G+ L + + A Q+ + F+ E N IH DL+ NIL+ + + KI DFG
Sbjct: 861 QTLEGVSLNLTR--KFAQQLCTALLFLATPEMNIIHCDLKPENILLCNPKRSAIKIVDFG 688
Query: 385 LARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVT 435
+ + Y + ++F + +PE + + + D+WS G +L E+ T
Sbjct: 687 SSCQLGQRIYQYIQ-SRF---YRSPEVLLGVPYDLAIDMWSLGCILVEMHT 547
>17286
Length = 489
Score = 39.7 bits (91), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 18/60 (30%), Positives = 35/60 (58%)
Frame = +3
Query: 57 PASPLQDNLVIALHSYEPSHDGDLGFEKGEQLRILEQSGEWWKAQSLTTGQEGFIPFNFV 116
P + ++ A++ + P DG+LGF++G+ + ++ Q E W S+ G+ G+ P N+V
Sbjct: 3 PTAGVKQPCARAIYDFLPESDGELGFQEGDMITLISQVDENWFEGSV-HGKVGYFPINYV 179
>29243
Length = 1147
Score = 39.7 bits (91), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 29/100 (29%), Positives = 47/100 (47%), Gaps = 2/100 (2%)
Frame = +2
Query: 114 NFVAKANSLEPEPWFFKNLSRKDAERQLLAPGNTHGSFLIRESES--TAGSFSLSVRDFD 171
++V + SLE W+ + R A++ L + G+FLIR + + G SLS++
Sbjct: 269 DYVNEPCSLESYNWYVGIMERPVAQKXLDTCPD--GTFLIRVTNNPLRRGELSLSIK--- 433
Query: 172 QNQGEVVKHYKIRNLDNGGFYISPRITFPGLHELVRHYTN 211
V+H K+ G FY++ F + LV HY N
Sbjct: 434 --YANAVRHIKVNRNPQGRFYLADGRYFDNIQSLVDHYEN 547
>32264
Length = 287
Score = 39.3 bits (90), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 18/45 (40%), Positives = 27/45 (60%)
Frame = +1
Query: 453 LERGYRMVRPDNCPEELYQLMRLCWKERPEDRPTFDYLRSVLEDF 497
+E GYR+ + P+ +Y+LM CW+ PE RP F L + L+D
Sbjct: 1 IEDGYRLQQNPQTPDSVYKLMLRCWEYVPEKRPHFKELYTSLKDI 135
>27287
Length = 514
Score = 37.0 bits (84), Expect = 0.018, Method: Compositional matrix adjust.
Identities = 15/43 (34%), Positives = 24/43 (55%)
Frame = -2
Query: 459 MVRPDNCPEELYQLMRLCWKERPEDRPTFDYLRSVLEDFFTAT 501
M +P E++ +M CW+E P DRP+F L L+ T++
Sbjct: 513 MKKPPYASSEMFGIMHSCWQEDPNDRPSFSRLVQELDKMLTSS 385
>21210
Length = 518
Score = 36.6 bits (83), Expect = 0.022, Method: Compositional matrix adjust.
Identities = 25/85 (29%), Positives = 42/85 (49%), Gaps = 3/85 (3%)
Frame = +3
Query: 409 PEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNP-EVIQNLERGYRMVRPDN--C 465
P A ++G + ++SDVWS GI L E+ T GR PY + + +Q + RG P +
Sbjct: 42 PRASSHG-YDVRSDVWSLGITLMELAT-GRFPYRKWVSIFDQLQQVVRGVAPCLPHDGAF 215
Query: 466 PEELYQLMRLCWKERPEDRPTFDYL 490
+ + C + + RP ++ L
Sbjct: 216 SHDFVNFVNKCLTKDEKQRPKYNKL 290
>32000
Length = 644
Score = 36.2 bits (82), Expect = 0.031, Method: Compositional matrix adjust.
Identities = 30/97 (30%), Positives = 48/97 (49%), Gaps = 3/97 (3%)
Frame = -1
Query: 375 TLSCKIADFGLARL--IEDNEYTAREGAKFPIKWTAPEAINYGTF-TIKSDVWSFGILLT 431
T KIADFGLAR+ + YT + + APE + F ++ D+WS G +
Sbjct: 581 TAKMKIADFGLARVFGLPVRTYTHEV---ITLWYRAPEILLGCRFYSVPVDIWSLGCIFV 411
Query: 432 EIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDNCPEE 468
E++T R +PG + +++ YR+ R P+E
Sbjct: 410 EMMTR-RALFPGDS------EIDQLYRIFRTLGTPDE 321
>36481
Length = 806
Score = 36.2 bits (82), Expect = 0.032, Method: Compositional matrix adjust.
Identities = 39/154 (25%), Positives = 66/154 (42%), Gaps = 13/154 (8%)
Frame = +2
Query: 235 EDEWEVPRET-----LKLVERLGAGQFGEV--WMGYYNGHTKVAVKSLKQGSMSPDAFLA 287
+D W R T +KL G G FG+V G +A+K +K +A
Sbjct: 323 KDIWCTMRGTSSTNDMKLCPHWGEGTFGKVVQCKDLLKG-DDIALKIIKNVDKYREAAKL 499
Query: 288 EANLMKQLQHQ------RLVRLYAVVTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKL 341
E N++++L+ + V++ I+ +M S+ DFLK S I ++
Sbjct: 500 EINVLEKLREKDPHAKHMCVQMLDWFDYHGHVCISFHMLGLSVFDFLKDNSYGAYPIEQV 679
Query: 342 LDMAAQIAEGMAFIEERNYIHRDLRAANILVSDT 375
++ Q+ + F+ E H DL+ NIL D+
Sbjct: 680 RHISYQLCYAVNFLHENQLTHTDLKPENILFVDS 781
>07933
Length = 728
Score = 35.4 bits (80), Expect = 0.049, Method: Compositional matrix adjust.
Identities = 14/29 (48%), Positives = 16/29 (55%)
Frame = +3
Query: 462 PDNCPEELYQLMRLCWKERPEDRPTFDYL 490
P+ CP LY +M CW P RPTF L
Sbjct: 3 PNYCPNLLYNIMMQCWSAEPSARPTFHKL 89
>38046
Length = 446
Score = 34.7 bits (78), Expect = 0.11, Method: Composition-based stats.
Identities = 14/25 (56%), Positives = 20/25 (80%)
Frame = -1
Query: 348 IAEGMAFIEERNYIHRDLRAANILV 372
IA+ MA++E+ N+IHR+L NILV
Sbjct: 98 IADAMAYMEKENFIHRNLGDRNILV 24
>20559
Length = 430
Score = 34.3 bits (77), Expect = 0.11, Method: Composition-based stats.
Identities = 21/67 (31%), Positives = 37/67 (55%), Gaps = 4/67 (5%)
Frame = -2
Query: 248 VERLGAGQFGEVWMGY-YNGHTKVAVKSLK---QGSMSPDAFLAEANLMKQLQHQRLVRL 303
+E++G G +G V+ H VA+K ++ P + L E L+K+L+H+ +VRL
Sbjct: 360 LEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHRNIVRL 181
Query: 304 YAVVTQE 310
+ V+ E
Sbjct: 180 HDVLHSE 160
>29590
Length = 320
Score = 33.9 bits (76), Expect = 0.17, Method: Composition-based stats.
Identities = 14/41 (34%), Positives = 27/41 (65%)
Frame = +3
Query: 406 WTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTN 446
+ APE ++Y +I++D+WS G+L ++T P+ G+T+
Sbjct: 72 YVAPEVLDYEPLSIQTDMWSLGVLSYVMLTACS-PFVGITS 191
>11228
Length = 2155
Score = 33.1 bits (74), Expect = 0.27, Method: Compositional matrix adjust.
Identities = 20/40 (50%), Positives = 25/40 (62%)
Frame = -1
Query: 127 WFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLS 166
W+ L R AE +LL + GS+L+RESES GSF LS
Sbjct: 1972 WYHGRLGRAGAE-ELLRDQDA-GSYLVRESESKLGSFVLS 1859
>37260
Length = 401
Score = 32.7 bits (73), Expect = 0.39, Method: Composition-based stats.
Identities = 19/69 (27%), Positives = 35/69 (50%)
Frame = -1
Query: 114 NFVAKANSLEPEPWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLSVRDFDQN 173
+F+ L+ W++ LS ++AE +L+ GSFL+R+S + SLS +
Sbjct: 221 DFLESMKQLKDCGWYWGPLSYEEAESKLM--DKRDGSFLVRDSSNENYILSLSFKSMGHV 48
Query: 174 QGEVVKHYK 182
++H+K
Sbjct: 47 HHTRIEHHK 21
>15741
Length = 402
Score = 32.3 bits (72), Expect = 0.53, Method: Composition-based stats.
Identities = 14/42 (33%), Positives = 20/42 (47%)
Frame = -3
Query: 330 TPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANIL 371
T + LT A +A GMA + +HRD+ A N+L
Sbjct: 127 TSTANDLTARDFFSFALHVARGMAHVANNKIVHRDVAARNVL 2
>13664
Length = 507
Score = 32.0 bits (71), Expect = 0.63, Method: Composition-based stats.
Identities = 16/56 (28%), Positives = 27/56 (48%)
Frame = +2
Query: 55 NPPASPLQDNLVIALHSYEPSHDGDLGFEKGEQLRILEQSGEWWKAQSLTTGQEGF 110
+P S + V+AL+ Y+ +L G+ + +L + E W L GQ+GF
Sbjct: 338 SPLGSTRKPKKVVALYDYKAQRSDELTILSGDVIMLLHKDSESWWMGELLDGQQGF 505
>06462
Length = 1511
Score = 30.8 bits (68), Expect = 1.2, Method: Compositional matrix adjust.
Identities = 30/116 (25%), Positives = 48/116 (41%), Gaps = 6/116 (5%)
Frame = +1
Query: 125 EPWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLSVRDFDQNQGEVVKHYKIR 184
E W+ +SR++AE+ L G FL+RES F LS ++ G+ + +
Sbjct: 1090 ELWYHGKMSRREAEKLL----GKDGDFLVRESGHNXSQFVLS----GKHHGQFI---HLL 1236
Query: 185 NLDNGGFYISPRITFPGLHELVRHYTN-----ASDGLCTRLSRPCQTQKPQ-KPWW 234
+D G + F + LV ++ + S G L RP P +P W
Sbjct: 1237 LVDPDGIVRTKDYIFDNISHLVSYHCHHGMPIVSHGSQLTLLRPINVSVPAYRP*W 1404
>20131
Length = 574
Score = 30.8 bits (68), Expect = 1.3, Method: Compositional matrix adjust.
Identities = 15/53 (28%), Positives = 28/53 (52%), Gaps = 1/53 (1%)
Frame = -2
Query: 67 IALHSYEPSHDGDLGFEKGEQLRILEQSGEWWKAQSLTTGQE-GFIPFNFVAK 118
+A++SY DL F +G+ + + ++ +WW T G++ G P +V K
Sbjct: 471 VAMYSYVSGETADLTFNEGDMILVTKKDEDWWTG---TLGEKTGMFPSTYVKK 322
>32357
Length = 625
Score = 30.8 bits (68), Expect = 1.4, Method: Compositional matrix adjust.
Identities = 17/52 (32%), Positives = 33/52 (63%), Gaps = 1/52 (1%)
Frame = -2
Query: 246 KLVERLGAGQFGEVWMGYYN-GHTKVAVKSLKQGSMSPDAFLAEANLMKQLQ 296
+L++++G+G FGE+++G +N +VAVK + + P + E+ L + LQ
Sbjct: 429 RLMKKIGSGSFGEIYLGVHNTSGEEVAVKLELKNAKHPQLYY-ESKLYRVLQ 277
>25100
Length = 699
Score = 28.9 bits (63), Expect = 5.4, Method: Compositional matrix adjust.
Identities = 11/38 (28%), Positives = 19/38 (50%)
Frame = +3
Query: 197 ITFPGLHELVRHYTNASDGLCTRLSRPCQTQKPQKPWW 234
+T+ + L+ +T+ L + SR C+ K K WW
Sbjct: 150 LTYCSSYILIHMHTDTHKDLFLKFSRKCRENKADKIWW 263
>18050
Length = 448
Score = 28.9 bits (63), Expect = 5.8, Method: Compositional matrix adjust.
Identities = 16/57 (28%), Positives = 29/57 (50%), Gaps = 1/57 (1%)
Frame = +3
Query: 66 VIALHSYEPSHDGDLGFEKGEQLRILEQSGE-WWKAQSLTTGQEGFIPFNFVAKANS 121
VIA HSYE L E G+ + + + + W++ + + G G+ P ++ + NS
Sbjct: 24 VIAKHSYESDEPDVLQLELGDVVNVSRKLPDGWYQGERIRDGAVGWFPGSYTEELNS 194
>17516
Length = 453
Score = 28.5 bits (62), Expect = 6.8, Method: Composition-based stats.
Identities = 27/104 (25%), Positives = 50/104 (48%), Gaps = 7/104 (6%)
Frame = -3
Query: 406 WTAPEAI-NYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRM-VRPD 463
+ APE + G + +K+DV+S I+L E+ +G+ +++ + LE + +RP
Sbjct: 421 YMAPEVLLQKGQYDMKADVYSLAIILWEL-WYGQDAADHISS-HLFGRLEDAVQAGLRPS 248
Query: 464 ---NC--PEELYQLMRLCWKERPEDRPTFDYLRSVLEDFFTATE 502
C P++ +L++ W+ RPT EDF T+
Sbjct: 247 VTMTCKPPDDWLKLLQSGWEFHASKRPTSRDAAEFFEDFLERTK 116
>30665
Length = 530
Score = 28.1 bits (61), Expect = 8.0, Method: Compositional matrix adjust.
Identities = 10/19 (52%), Positives = 17/19 (89%)
Frame = +3
Query: 312 IYIITEYMENGSLVDFLKT 330
++++TE+ ENGSL D+LK+
Sbjct: 441 LWLLTEFHENGSLSDYLKS 497
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000383401 | hsapiens_gene_ensembl |
Serine/threonine-protein phosphatase 4 regulatory subunit 1.
[Source:Uniprot/SWISSPROT;Acc:Q8TF05]
(933 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
01469 300 2e-81
25614 172 5e-43
19245 170 3e-42
25537 123 3e-28
19229 117 2e-26
26856 54 4e-07
34109 31 1.9
20201 30 6.0
>01469
Length = 2023
Score = 300 bits (768), Expect = 2e-81, Method: Compositional matrix adjust.
Identities = 156/343 (45%), Positives = 221/343 (64%), Gaps = 3/343 (0%)
Frame = +1
Query: 589 DEERRTKVQDVVPQALLDQYLSMTDPSRAQTVDTEIAKHCAYSLPGVALTLGRQNWHCLR 648
D+ + QD++PQ+LL+ YL M +PSRAQTVDTEI +HCAY+LP VA TLGRQNWHC++
Sbjct: 262 DDSILAQQQDIIPQSLLENYLGMVEPSRAQTVDTEITRHCAYNLPAVAYTLGRQNWHCIK 441
Query: 649 ETYETLASDMQWKVRRTLAFSIHELAVILGDQLTAADLVPIFNGFLKDLDEVRIGVXXXX 708
YETLA MQWKVRRTLAFSIHE+A+I G+ +T DL+P+F+GF+KDLDEVRIGV
Sbjct: 442 HLYETLAQAMQWKVRRTLAFSIHEMALIEGEAITHNDLLPVFDGFIKDLDEVRIGVLKHL 621
Query: 709 XXXXXXXXXXXRREYLYQLQEFLVTDNSRNWRFRXXXXXXXXXXXXXYSPRDVYDYLRPI 768
R++YL ++ +F+ TDN RNWRFR + PR + ++ P+
Sbjct: 622 ADFLRLLRPNVRQQYLAKVSDFMKTDNHRNWRFRKELSEQLIYLCELFDPRSIVRHICPL 801
Query: 769 ALNLCADKVSSVRWISYKLVSEMVKKLHAATPPTFGVDLINELVENFGRCPKWSGRQAFV 828
A+ LC DKV+ VR +S+ L+S +++++H + ++L + F KW GRQ +
Sbjct: 802 AVALCMDKVAEVRAVSFGLMSAVLRRVHEEGEDKLLQVICSDLSDQFALNIKWLGRQIYC 981
Query: 829 FVCQTVIEDDCLPMDQFAVHLMPHLLTLANDRVPNVRVLLAKTLRQTLLEKDYFLASAS- 887
+C V+ D+ +P FA L+P LL L D +PNVR+ LAK L Q + DYF +S +
Sbjct: 982 QMCLVVLADNAVPPPVFAELLLPGLLALGTDAIPNVRLTLAKVLAQRVAPLDYFTSSQNP 1161
Query: 888 CHQEAVEQTIMALQMDRDSDVKYFAS--IHPASTKISEDAMST 928
CH EA+ T+ AL+ D+D DV+YF+S + P++T + A T
Sbjct: 1162CH-EALLTTLQALKTDKDQDVRYFSSQQVDPSATADVQHAYDT 1287
>25614
Length = 433
Score = 172 bits (437), Expect = 5e-43, Method: Composition-based stats.
Identities = 75/118 (63%), Positives = 96/118 (81%)
Frame = -2
Query: 195 LILPRFCEMCCDCRMFHVRKVCAANFGDICSVVGQQATEEMLLPRFFQLCSDNVWGVRKA 254
++LPRF +M D +FHVRKVCAANFG++CSVVG+Q++EE+LLP+ LC D VWGVRKA
Sbjct: 411 VLLPRFSQMLTD-PLFHVRKVCAANFGEVCSVVGKQSSEELLLPKLNSLCEDGVWGVRKA 235
Query: 255 CAECFMAVSCATCQEIRRTKLSALFINLISDPSRWVRQAAFQSLGPFISTFANPSSSG 312
CAECFMA+SCA E RR L+ LF++L++D SRWVR +AFQ LGPFISTFA+ + +G
Sbjct: 234 CAECFMAISCACSLETRRGYLARLFVHLLADQSRWVRMSAFQHLGPFISTFAHAAHTG 61
>19245
Length = 1339
Score = 170 bits (430), Expect = 3e-42, Method: Compositional matrix adjust.
Identities = 96/276 (34%), Positives = 142/276 (51%), Gaps = 13/276 (4%)
Frame = +2
Query: 431 LDQELYNSFHFWRTPLPEIDLDIELEQNXXXXXXXXXXXXXXXXXXXXXXNITMATRKEL 490
LD +N+F +WR PLP++D+D ++ ++ + K+
Sbjct: 587 LDNCNFNTFQYWRPPLPQVDIDFDVINGAPANIHVVAKVKDEEKHKVYSTHVDVVMSKDS 766
Query: 491 EEMIENLEPHIDDPDVKAQVEVXXXXXXXXXXDAHEETISIEKRSDLQDELD-------- 542
E + I D ++ +++ H T S+ SD + +
Sbjct: 767 AEASASSVHQISDGAMRRDMDLAG---------VHIHTASVSTVSDTDETVSNIGSTNIL 919
Query: 543 INELPNCKINQEDSVPLISD-----AVENMDSTLHYIHXXXXXXXXXXXXPDEERRTKVQ 597
+ L C + D V + D ++ MD+ H + D+ + Q
Sbjct: 920 GDNLGECTLAVVDGV--VKDLSGGSSIGYMDAAHHQV--------------DDSILAQQQ 1051
Query: 598 DVVPQALLDQYLSMTDPSRAQTVDTEIAKHCAYSLPGVALTLGRQNWHCLRETYETLASD 657
D++PQ+LL+ YL M +PSRAQTVDTEI +HCAY+LP VA TLGRQNWHC++ YETLA
Sbjct: 1052DIIPQSLLENYLGMVEPSRAQTVDTEITRHCAYNLPAVAYTLGRQNWHCIKHLYETLAQA 1231
Query: 658 MQWKVRRTLAFSIHELAVILGDQLTAADLVPIFNGF 693
MQWKVRRTLAFSIHE+A+I G+ +T DL+P+F+GF
Sbjct: 1232MQWKVRRTLAFSIHEMALIEGEAITHNDLLPVFDGF 1339
>25537
Length = 487
Score = 123 bits (309), Expect = 3e-28, Method: Composition-based stats.
Identities = 52/81 (64%), Positives = 64/81 (79%)
Frame = +1
Query: 234 EMLLPRFFQLCSDNVWGVRKACAECFMAVSCATCQEIRRTKLSALFINLISDPSRWVRQA 293
E+LLP+F+ LC D VWGVRKACAECFM +SCA E RR L+ LF++L++D SRWVR +
Sbjct: 1 EVLLPKFYNLCGDGVWGVRKACAECFMTISCACSLETRRQYLANLFVDLLADQSRWVRMS 180
Query: 294 AFQSLGPFISTFANPSSSGQY 314
AFQ LGPFISTFA+P +G Y
Sbjct: 181 AFQQLGPFISTFADPRLTGLY 243
Score = 57.4 bits (137), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 29/66 (43%), Positives = 44/66 (66%), Gaps = 9/66 (13%)
Frame = +2
Query: 63 DERDCIAVLERISRLADDSEPTVRAELMEQVPHIALFCQEN--------RPS-IPYAFSK 113
D+ + A+ E +RL+ D+EP+VR+ELMEQVPHIA++CQE RP+ P++F+
Sbjct: 275 DQGEAPALTESGARLSHDAEPSVRSELMEQVPHIAVYCQETKVSSQMPCRPTYCPWSFAI 454
Query: 114 FLLPIV 119
+PI
Sbjct: 455 STMPIT 472
Score = 30.0 bits (66), Expect = 4.9, Method: Composition-based stats.
Identities = 12/20 (60%), Positives = 15/20 (75%)
Frame = +1
Query: 110 AFSKFLLPIVVRYLADQNNQ 129
A ++LP+VVRYL D NNQ
Sbjct: 415 AMPTYILPMVVRYLNDANNQ 474
>19229
Length = 470
Score = 117 bits (294), Expect = 2e-26, Method: Compositional matrix adjust.
Identities = 49/77 (63%), Positives = 60/77 (77%)
Frame = -2
Query: 238 PRFFQLCSDNVWGVRKACAECFMAVSCATCQEIRRTKLSALFINLISDPSRWVRQAAFQS 297
P+F+ LC D VWGVRKACAECFM +SCA E RR L+ LF++L++D SRWVR +AFQ
Sbjct: 469 PKFYNLCGDGVWGVRKACAECFMTISCACSLETRRQYLANLFVDLLADQSRWVRMSAFQQ 290
Query: 298 LGPFISTFANPSSSGQY 314
LGPFISTFA+P +G Y
Sbjct: 289 LGPFISTFADPRLTGLY 239
>26856
Length = 2013
Score = 53.5 bits (127), Expect = 4e-07, Method: Compositional matrix adjust.
Identities = 41/159 (25%), Positives = 74/159 (46%), Gaps = 4/159 (2%)
Frame = +1
Query: 152 VETKVCPVLIELTAPDSNDDVKTEAVAIMCKMAPMVGKDITERLILPRFCEM----CCDC 207
+ T + P + +L A D+N VK+ +++ ++P++GKD T +LP F C D
Sbjct: 760 IMTNILPCVKDLVA-DANQHVKSALASVIMGLSPILGKDNTIEHLLPLFLSQLKDECPDV 936
Query: 208 RMFHVRKVCAANFGDICSVVGQQATEEMLLPRFFQLCSDNVWGVRKACAECFMAVSCATC 267
R+ + +N + V+G + + LLP +L D W VR A E ++
Sbjct: 937 RLNII-----SNLDCVNEVIGIKQLSQSLLPAIVELAEDTKWRVRLAIIEYMPLLAGQLG 1101
Query: 268 QEIRRTKLSALFINLISDPSRWVRQAAFQSLGPFISTFA 306
+ KL++L + + D +R+AA +L + F
Sbjct: 1102VQFFDEKLNSLCMTWLVDHVFAIREAATLNLKKLVEKFG 1218
Score = 42.0 bits (97), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 62/261 (23%), Positives = 101/261 (38%), Gaps = 1/261 (0%)
Frame = +1
Query: 654 LASDMQWKVRRTLAFSIHELAVILGDQLTAADLVPIFNGFLKD-LDEVRIGVXXXXXXXX 712
L +D V+ LA I L+ ILG T L+P+F LKD +VR+ +
Sbjct: 793 LVADANQHVKSALASVIMGLSPILGKDNTIEHLLPLFLSQLKDECPDVRLNIISNLDCVN 972
Query: 713 XXXXXXXRREYLYQLQEFLVTDNSRNWRFRXXXXXXXXXXXXXYSPRDVYDYLRPIALNL 772
+ L L D WR R + + L + +
Sbjct: 973 EVIGIKQLSQSLLPAIVELAEDT--KWRVRLAIIEYMPLLAGQLGVQFFDEKLNSLCMTW 1146
Query: 773 CADKVSSVRWISYKLVSEMVKKLHAATPPTFGVDLINELVENFGRCPKWSGRQAFVFVCQ 832
D V ++R + + ++V+K P + + + V + + + R +F
Sbjct: 1147 LVDHVFAIREAATLNLKKLVEKFG----PEWAQETVIPKVTSMSKDSNYLHRMTCLFSIN 1314
Query: 833 TVIEDDCLPMDQFAVHLMPHLLTLANDRVPNVRVLLAKTLRQTLLEKDYFLASASCHQEA 892
+ E + + + L+P LA D VPNVR AKT L+K L S Q
Sbjct: 1315 LLAET--MGQELTSKLLLPTRF-LARDTVPNVRFNAAKT-----LQKIAPLLDQSTVQSQ 1470
Query: 893 VEQTIMALQMDRDSDVKYFAS 913
V+ + L+ D D DV++FA+
Sbjct: 1471 VKPILETLKSDSDIDVQFFAA 1533
Score = 37.4 bits (85), Expect = 0.030, Method: Compositional matrix adjust.
Identities = 21/53 (39%), Positives = 28/53 (52%), Gaps = 1/53 (1%)
Frame = +1
Query: 650 TYETLASDMQWKVRRTLAFSIHELAVILGDQLTAADLVPIFNGFLKDLD-EVR 701
T + D W+VR +A EL +G ++T DLVP F LKD + EVR
Sbjct: 535 TLRQASEDKSWRVRYMVADKFTELQKAVGPEITKNDLVPAFQSLLKDCEAEVR 693
Score = 34.3 bits (77), Expect = 0.25, Method: Compositional matrix adjust.
Identities = 38/176 (21%), Positives = 69/176 (39%), Gaps = 1/176 (0%)
Frame = +1
Query: 111 FSKFLLPIVVRYLADQNNQVRKTSXXXXXXXXXXXXIERFDVE-TKVCPVLIELTAPDSN 169
S+ LLP +V D +VR ++ FD + +C + D
Sbjct: 994 LSQSLLPAIVELAEDTKWRVRLAIIEYMPLLAGQLGVQFFDEKLNSLCMTWL----VDHV 1161
Query: 170 DDVKTEAVAIMCKMAPMVGKDITERLILPRFCEMCCDCRMFHVRKVCAANFGDICSVVGQ 229
++ A + K+ G + + ++P+ M D H R C + + +GQ
Sbjct: 1162 FAIREAATLNLKKLVEKFGPEWAQETVIPKVTSMSKDSNYLH-RMTCLFSINLLAETMGQ 1338
Query: 230 QATEEMLLPRFFQLCSDNVWGVRKACAECFMAVSCATCQEIRRTKLSALFINLISD 285
+ T ++LLP F L D V VR A+ ++ Q ++++ + L SD
Sbjct: 1339 ELTSKLLLPTRF-LARDTVPNVRFNAAKTLQKIAPLLDQSTVQSQVKPILETLKSD 1503
Score = 33.9 bits (76), Expect = 0.31, Method: Compositional matrix adjust.
Identities = 49/222 (22%), Positives = 79/222 (35%), Gaps = 2/222 (0%)
Frame = +1
Query: 647 LRETYETLASDMQWKVRRTLAFSIHELAVILGDQLTAADLVPIFNGFLKD-LDEVR-IGV 704
LR+ + L SD VRR A + E A + + +DL+P+F +D D VR + V
Sbjct: 292 LRQLFRNLCSDDTPMVRRAAAGKLGEFAKEVESEFLKSDLIPLFAMLAQDEQDSVRLLAV 471
Query: 705 XXXXXXXXXXXXXXXRREYLYQLQEFLVTDNSRNWRFRXXXXXXXXXXXXXYSPRDVYDY 764
+ + L++ ++WR R P +
Sbjct: 472 EACVSIASLLPSEDTEQLVMPTLRQ---ASEDKSWRVRYMVADKFTELQKAVGPEITKND 642
Query: 765 LRPIALNLCADKVSSVRWISYKLVSEMVKKLHAATPPTFGVDLINELVENFGRCPKWSGR 824
L P +L D + VR S V + + L T + I V++ +
Sbjct: 643 LVPAFQSLLKDCEAEVRAASANKVKDFCQALSPDVRETIIMTNILPCVKDLVADANQHVK 822
Query: 825 QAFVFVCQTVIEDDCLPMDQFAVHLMPHLLTLANDRVPNVRV 866
A V + L D HL+P L+ D P+VR+
Sbjct: 823 SALASVIMGL--SPILGKDNTIEHLLPLFLSQLKDECPDVRL 942
>34109
Length = 684
Score = 31.2 bits (69), Expect = 1.9, Method: Composition-based stats.
Identities = 17/55 (30%), Positives = 29/55 (52%)
Frame = +1
Query: 600 VPQALLDQYLSMTDPSRAQTVDTEIAKHCAYSLPGVALTLGRQNWHCLRETYETL 654
+P +D+Y +D + AQT+D+ KHC S A T+ HC + + +T+
Sbjct: 457 LPHKKMDRYKKQSDQTSAQTIDSH-QKHCDRS---TAQTIDNHQKHCDQSSTQTI 609
>20201
Length = 557
Score = 29.6 bits (65), Expect = 6.0, Method: Composition-based stats.
Identities = 17/70 (24%), Positives = 33/70 (47%)
Frame = -3
Query: 819 PKWSGRQAFVFVCQTVIEDDCLPMDQFAVHLMPHLLTLANDRVPNVRVLLAKTLRQTLLE 878
P+W + + + ++V+ D L + F VHL P +L P ++++L
Sbjct: 243 PEWFSTEFSLSILKSVLSDPLLAVSNFLVHLTPIILFFFTF*DPQLKLILP--------- 91
Query: 879 KDYFLASASC 888
D+F ++SC
Sbjct: 90 HDHFSFASSC 61
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000348194 | hsapiens_gene_ensembl | Proto-oncogene
tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK) (Lymphocyte
cell-specific protein-tyrosine kinase) (LSK) (T cell- specific
protein-tyrosine kinase). [Source:Uniprot/SWISSPROT;Acc:P06239]
(496 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
06405 298 3e-81
21808 284 3e-77
11780 206 4e-73
04852 162 4e-40
09007 158 4e-39
07291 139 3e-33
17300 123 2e-31
20640 124 7e-29
14116 121 6e-28
07940 110 1e-24
18996 107 7e-24
17637 105 4e-23
22005 84 6e-23
08294 104 9e-23
14477 94 1e-19
01718 91 9e-19
19301 86 3e-17
13305 84 1e-16
13592 78 9e-15
18921 77 1e-14
12721 77 1e-14
07833 77 1e-14
01060 76 3e-14
29581 75 4e-14
17253 73 3e-13
14126 73 3e-13
01707 72 5e-13
01756 69 6e-12
00300 68 6e-12
00715 67 1e-11
01966 65 6e-11
14420 65 7e-11
27546 64 1e-10
18484 64 2e-10
12672 63 2e-10
04591 61 1e-09
25550 60 1e-09
07836 59 3e-09
31885 57 2e-08
17975 57 3e-08
13066 56 3e-08
19094 55 5e-08
09606 55 7e-08
03240 54 1e-07
30755 51 1e-06
21079 51 1e-06
15910 50 3e-06
04138 49 3e-06
13212 49 3e-06
26711 47 1e-05
35671 47 3e-05
01392 45 5e-05
19761 45 7e-05
16708 45 8e-05
37602 45 8e-05
26560 44 1e-04
27405 42 5e-04
11185 42 5e-04
21433 42 6e-04
12786 40 0.001
18481 40 0.002
28638 40 0.002
17286 40 0.003
29243 40 0.003
32264 39 0.003
27287 37 0.017
36481 37 0.021
21210 37 0.021
32000 36 0.030
07933 36 0.046
38046 34 0.11
20559 34 0.12
29590 34 0.15
11228 33 0.27
37260 33 0.33
15741 32 0.51
06462 31 1.1
20131 31 1.3
32357 31 1.4
13664 30 2.1
25100 29 5.5
17516 28 6.0
18050 28 6.2
30665 28 7.1
>06405
Length = 1965
Score = 298 bits (764), Expect = 3e-81, Method: Compositional matrix adjust.
Identities = 161/352 (45%), Positives = 229/352 (65%), Gaps = 8/352 (2%)
Frame = +1
Query: 142 ESESTAGSFSLSVRDFDQNQGEVVKHYKIRNLDNGGFYISPRITFPGLHELVRHYTNASD 201
ESES+ G S+SVR F+ V HY+I D+G +++ F L ELV H++ +D
Sbjct: 1 ESESSPGQRSISVR-FEGR----VYHYRITE-DDGKVFVTQEHRFNTLAELVHHHSIHAD 162
Query: 202 GLCTRLSRPCQTQKPQKPWW------EDEWEVPRETLKLVERLGAGQFGEVWMGYYNGHT 255
GL T L P K QKP D WE+ R + + RLG GQ+G+V+ + +
Sbjct: 163 GLVTTLLYPAP--KRQKPTVFGVSPEPDRWEIERTEIAMKHRLGGGQYGDVYEAMWKRYN 336
Query: 256 K-VAVKSLKQGSMSPDAFLAEANLMKQLQHQRLVRLYAVVTQEP-IYIITEYMENGSLVD 313
K VAVK+LK+ +M+ + FL EA +MK+++H LV+L V T+EP YI+TE+M +G+L+D
Sbjct: 337 KIVAVKTLKEDTMALNDFLEEAAIMKEMKHPNLVQLLGVCTREPPFYIVTEFMPHGNLLD 516
Query: 314 FLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLA 373
+L++ + + L+ MA QIA GMA++E +N+IHRDL A N LV+D+ K+ADFGLA
Sbjct: 517 YLRSSTREENGPTALMYMATQIASGMAYLETKNFIHRDLAARNCLVADSNMVKVADFGLA 696
Query: 374 RLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTN 433
RL++D+ YTA GAKFPIKWTAPE + + F+ +SD+W+FG+LL E+ T+G PYPG+
Sbjct: 697 RLMKDDTYTAHIGAKFPIKWTAPEGLAFNRFSTRSDIWAFGVLLWELATYGMSPYPGVEL 876
Query: 434 PEVIQNLERGYRMVRPDNCPEELYQLMRLCWKERPEDRPTFDYLRSVLEDFF 485
EV LERGYRM RP P ++Y LM CW+ P+DRPTF + +LE+ F
Sbjct: 877 TEVYHLLERGYRMERPPGTPADVYILMLKCWQWDPKDRPTFKEIHFLLENMF 1032
>21808
Length = 1011
Score = 284 bits (726), Expect(2) = 3e-77, Method: Compositional matrix adjust.
Identities = 138/225 (61%), Positives = 175/225 (77%), Gaps = 1/225 (0%)
Frame = +1
Query: 249 GYYNGHTKVAVKSLKQGSMSPDAFLAEANLMKQLQHQRLVRLYAVVTQE-PIYIITEYME 307
G +N T VA+K+LK G+M P FLAEA +MK+L+H +L++LYAV TQ+ PI+IITE M+
Sbjct: 4 GLWNNTTPVAIKTLKSGTMDPKDFLAEAQIMKKLRHPKLIQLYAVCTQDDPIFIITELMK 183
Query: 308 NGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKI 367
NGSL++FL+ G L + L+D+ AQIA GMA++E +NYIHRDL A NILVSD + KI
Sbjct: 184 NGSLLEFLQG-KGRVLKLPALIDIGAQIACGMAYLESQNYIHRDLAARNILVSDNNTVKI 360
Query: 368 ADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIP 427
ADFGLAR+I+++EY AR GA+FPIKWTAPEA NY FTIKSDVWSFGILLTE VT+GR+P
Sbjct: 361 ADFGLARVIKEDEYEARVGARFPIKWTAPEAANYNRFTIKSDVWSFGILLTETVTYGRVP 540
Query: 428 YPGMTNPEVIQNLERGYRMVRPDNCPEELYQLMRLCWKERPEDRP 472
YPGMTN EV+ +E GYRM P CP+ LY +M CW++ +RP
Sbjct: 541 YPGMTNAEVLHQVEHGYRMPCPPGCPKPLYDIMLECWRKEEMERP 675
Score = 23.5 bits (49), Expect(2) = 3e-77, Method: Compositional matrix adjust.
Identities = 10/22 (45%), Positives = 14/22 (63%)
Frame = +2
Query: 472 PTFDYLRSVLEDFFTATEGQYQ 493
PTF+ L+ LE+FFT Y+
Sbjct: 674 PTFETLQWKLEEFFTMDSKDYR 739
>11780
Length = 1713
Score = 206 bits (524), Expect(2) = 4e-73, Method: Compositional matrix adjust.
Identities = 126/341 (36%), Positives = 189/341 (55%), Gaps = 10/341 (2%)
Frame = +3
Query: 69 FEKGEQLRILEQSGE--WWKAQSLTTGQEGFIPFNFVA--KANSLEPEPWFFKNLSRKDA 124
F+KG+ L I + + W+KA + G+EG IP N+V K +L PWF ++R+ A
Sbjct: 111 FQKGDLLVIRRATSDRMWYKACD-SNGREGMIPANYVQPRKVVTLHAMPWFHGKITRQQA 287
Query: 125 ERQLLAPGNTHGSFLIRESESTAGSFSLSVRDFDQNQGEVVKHYKIRNLDNGGFYISPRI 184
E +LL P G FLIRES + G ++L V + V+HY+I +N I
Sbjct: 288 E-ELLKP-REDGLFLIRESSNYPGDYTLCVCHLGK-----VEHYRILYRENQ-LTIDEEG 443
Query: 185 TFPGLHELVRHYTNASDGLCTRLSRPCQTQKPQ------KPWWEDEWEVPRETLKLVERL 238
F L ELV+HY +DGLCT+L+RP Q + + W + + L++ E +
Sbjct: 444 FFRNLDELVKHYLADADGLCTQLTRPVTKQGGNFGTVSLQEFKSGGWVIAXQDLEIGEAI 623
Query: 239 GAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPDAFLAEANLMKQLQHQRLVRLYAVVTQEP 298
G G FG+V+ G Y G VA+K LK +FL EA++M L+H LVRL VV E
Sbjct: 624 GKGDFGDVYKGMYRGQP-VAIKQLKDKDRGEQSFLQEASVMTSLRHDNLVRLIGVVLGET 800
Query: 299 IYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANIL 358
I+++TE+M G+LV++L++ +T ++ A M ++E + +HRDL A N+L
Sbjct: 801 IFLVTEFMGKGNLVEYLRSRGRSVITKKDQINFATDTCAAMEYLESKRLVHRDLAARNVL 980
Query: 359 VSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAI 399
V D K++DFGLA+ + ++ + KFPIKWTAPEA+
Sbjct: 981 VHDDGKAKVSDFGLAKFGDFSQTS----VKFPIKWTAPEAL 1091
Score = 87.0 bits (214), Expect(2) = 4e-73, Method: Compositional matrix adjust.
Identities = 39/80 (48%), Positives = 56/80 (70%)
Frame = +1
Query: 404 FTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDNCPEELYQLMRLC 463
FT KSD+WSFGILL EI + GR+PYP + +V+ ++ERGYRM P+ CP E+Y +M+
Sbjct: 1105 FTSKSDMWSFGILLWEIYSFGRVPYPRIPLTDVVMHVERGYRMEAPEGCPPEIYSIMKQA 1284
Query: 464 WKERPEDRPTFDYLRSVLED 483
W+ P +RPTF + + L +
Sbjct: 1285 WELDPNERPTFKSVLARLNN 1344
>04852
Length = 1462
Score = 162 bits (409), Expect = 4e-40, Method: Compositional matrix adjust.
Identities = 98/254 (38%), Positives = 133/254 (52%), Gaps = 31/254 (12%)
Frame = +1
Query: 255 TKVAVKSLKQ--GSMSPDAFLAEANLMKQLQ----HQRLVRLYAVVTQE-PIYIITEYME 307
+ VAVK L+ ++ F+ E +MK ++ H +V TQ P+++I E+ +
Sbjct: 22 STVAVKMLRDIVTAVEEQDFVQELQVMKAVKKMGSHINIVNFLGCCTQGGPLWVIVEFAK 201
Query: 308 NGSLVDFL-----------------------KTPSGIKLTINKLLDMAAQIAEGMAFIEE 344
NG+L DFL KTP G + LL A QIA GM F+
Sbjct: 202 NGNLRDFLESCRDGINGYGKFVSPQDPGWYTKTPGGHVIRRKNLLSYAFQIARGMEFLAS 381
Query: 345 RNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTF 404
R IHRDL A N+LV++ KIADFGL+R + Y R G + P+KW APEA+ +
Sbjct: 382 RKCIHRDLAARNVLVTEEHVLKIADFGLSR--TGDYYKKRSGGRLPVKWMAPEALFDMRY 555
Query: 405 TIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQN-LERGYRMVRPDNCPEELYQLMRLC 463
T KSDVWSFG++L EI + G +PY + N E+ L+ YRM RP+ LY +M C
Sbjct: 556 TTKSDVWSFGVVLWEIFSLGGMPYASIPNEELYSKLLDDAYRMPRPELASGNLYAIMERC 735
Query: 464 WKERPEDRPTFDYL 477
W RP DRP F L
Sbjct: 736 WLNRPSDRPEFSQL 777
>09007
Length = 1440
Score = 158 bits (400), Expect = 4e-39, Method: Compositional matrix adjust.
Identities = 88/266 (33%), Positives = 145/266 (54%), Gaps = 15/266 (5%)
Frame = -1
Query: 227 VPRETLKLVERLGAGQFGEV----WMGYYNGHTKVAVKSLKQGSMSPDA--FLAEANLMK 280
+ ++ + L + LG G FG V W +VAVK L + + D FL E +M+
Sbjct: 888 ISKDCVALSKSLGQGHFGTVRQAIWTAESGEKVQVAVKCLSKDKIHKDGQEFLKETAIMQ 709
Query: 281 QLQHQRLVRLYAVVTQE--PIYIITEYMENGSLVDFLKTPSG-IKLTINKLLDMAAQIAE 337
L H+ +VR+Y VV I ++TE SL++ +K S + ++ +L D + Q+ +
Sbjct: 708 MLDHENIVRVYGVVMDNGADIMLVTELAPMRSLLECVKEVSARVDFSVPRLCDFSQQVCD 529
Query: 338 GMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLA-RLIEDNEYTAREGA---KFPIKW 393
GM+++E + +HRDL A NIL+ KI+D G++ L EY + + + W
Sbjct: 528 GMSYLESKRLVHRDLAARNILLFSKSKVKISDVGVSGALGAGKEYYQSQQTIHLQNAVAW 349
Query: 394 TAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLE--RGYRMVRPDN 451
APE+ F+ SDVW+FG+LL E THG P+ G+ ++++ ++ + R+ +PD
Sbjct: 348 CAPESFRNLCFSSASDVWAFGVLLWEFFTHGFQPWAGLNGQQIMEAVDAPQSQRLEQPDL 169
Query: 452 CPEELYQLMRLCWKERPEDRPTFDYL 477
CP+E Y +M CW++ P+ RPTF L
Sbjct: 168 CPKEYYAVMLKCWEQEPQRRPTFSQL 91
>07291
Length = 833
Score = 139 bits (349), Expect = 3e-33, Method: Compositional matrix adjust.
Identities = 67/164 (40%), Positives = 104/164 (63%), Gaps = 2/164 (1%)
Frame = +1
Query: 323 LTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGL-ARLIEDNEY 381
LT+ +LLD QIA+GMA+++E +HR+L A N +V++ +++D+G+ L + Y
Sbjct: 40 LTVVQLLDFGRQIADGMAYLQEVKVVHRNLAARNCIVTEDGRLQLSDYGVTGSLFPQSYY 219
Query: 382 TAREG-AKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNL 440
TA + A+ +KW APE I+ F+ KSDVW+FG++L E++T G PYP + N ++ L
Sbjct: 220 TADDSPARDLVKWMAPETIDNFHFSSKSDVWAFGVVLWELLTRGITPYPDVENSSLLPYL 399
Query: 441 ERGYRMVRPDNCPEELYQLMRLCWKERPEDRPTFDYLRSVLEDF 484
+ G+RM +P PE +Y++M CW E PE RP F L L+ F
Sbjct: 400 KEGHRMKKPKQSPEPVYEMMTACWNESPEQRPDFAELNDQLKTF 531
>17300
Length = 480
Score = 123 bits (308), Expect(2) = 2e-31, Method: Compositional matrix adjust.
Identities = 57/116 (49%), Positives = 82/116 (70%), Gaps = 4/116 (3%)
Frame = +1
Query: 335 IAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDN----EYTAREGAKFP 390
I+ GM + + Y+HRDL A NILV++ L CK+ADFGL+R IE + YT + G K P
Sbjct: 1 ISSGMGXLADMGYVHRDLAARNILVNEILVCKVADFGLSREIESDTTEGAYTTK-GGKIP 177
Query: 391 IKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRM 446
++WTAPEAI Y FT SDVWSFG+++ E++++G PY +N +VI+ +E+GYR+
Sbjct: 178 VRWTAPEAIAYRKFTSASDVWSFGVVMWEVMSYGERPYWNWSNQDVIKAVEKGYRL 345
Score = 30.8 bits (68), Expect(2) = 2e-31, Method: Composition-based stats.
Identities = 13/39 (33%), Positives = 19/39 (48%)
Frame = +2
Query: 451 NCPEELYQLMRLCWKERPEDRPTFDYLRSVLEDFFTATE 489
+CPE L+QLM W++ RP + L+ A E
Sbjct: 356 DCPEALHQLMLDAWQKERSHRPKMSMVVKTLDKLIRAPE 472
>20640
Length = 1492
Score = 124 bits (312), Expect = 7e-29, Method: Compositional matrix adjust.
Identities = 61/146 (41%), Positives = 84/146 (57%), Gaps = 1/146 (0%)
Frame = +1
Query: 345 RNYIHRDLRAANILVSDTLSCKIADFGLARLIED-NEYTAREGAKFPIKWTAPEAINYGT 403
R Y+HRDL N LV L KI+DFGLAR + + Y E PI+W EAI Y
Sbjct: 1 RGYVHRDLATRNCLVGHDLVVKISDFGLARSVHSVDYYRGSEHDAIPIRWMPLEAILYNK 180
Query: 404 FTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDNCPEELYQLMRLC 463
F+ +SDVWSFG++L EI PY G+T+ EV++ ++ G + P+ P +Y+LM+ C
Sbjct: 181 FSTQSDVWSFGVVLWEIFAFALQPYYGLTHEEVVRFVKEGKVLACPERTPPPMYELMKQC 360
Query: 464 WKERPEDRPTFDYLRSVLEDFFTATE 489
W RP RP+F L LE+ + E
Sbjct: 361 WHRRPATRPSFHTLHKTLENMHSKYE 438
>14116
Length = 1017
Score = 121 bits (304), Expect = 6e-28, Method: Compositional matrix adjust.
Identities = 72/216 (33%), Positives = 117/216 (54%), Gaps = 13/216 (6%)
Frame = -1
Query: 227 VPRETLKLVERLGAGQFGEVWMGYYN-----GHTKVAVKSLKQGS---MSPDAFLAEANL 278
+ RE L + E +G G FG V G+ G VAVK+L + + +FL EA +
Sbjct: 645 IDREFLTMGEEIGKGNFGCVKRGFLTLPEQKGDILVAVKTLHNNNPREIELQSFLQEALI 466
Query: 279 MKQLQHQRLVRLYAV---VTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQI 335
MK H ++ L + + P+ ++ +M++G L+ +++ + TI L+ I
Sbjct: 465 MKDFHHSNVLTLIGICLNLDDMPL-VVLPFMKHGDLLTYIRDDQH-QPTIKDLIMYGVDI 292
Query: 336 AEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREG--AKFPIKW 393
A GM ++ ++HRDL A N ++ + K+ADFGLAR I + EY + E AK P+KW
Sbjct: 291 ARGMDYLAGLKFVHRDLAARNCMLDEDFHVKVADFGLARDIYEKEYYSSENKKAKLPVKW 112
Query: 394 TAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYP 429
A E++ G + K+DVWS+G++L E++T G P
Sbjct: 111 MALESLEKGNYDSKTDVWSYGVVLWELLTRGSDALP 4
>07940
Length = 1336
Score = 110 bits (276), Expect = 1e-24, Method: Compositional matrix adjust.
Identities = 84/280 (30%), Positives = 128/280 (45%), Gaps = 70/280 (25%)
Frame = -3
Query: 222 EDEWEVPRETLKLVERLGAGQFGEVW----MGYY--NGHTKVAVKSLKQGSMSPDA--FL 273
+ +WE PRE L L +RLG G FG V MG + N VAVK LK+ + + +
Sbjct: 866 DAKWEFPRERLVLGDRLGEGAFGLVMKGEAMGIFKDNNSVTVAVKMLKEDATDREMMDLI 687
Query: 274 AEANLMKQL-QHQRLVRL----------YAVVTQEPIYIITEYMEN-------------- 308
E +MK + +H+ ++ L Y +V P + +++++
Sbjct: 686 REMEMMKVIGKHKNIINLLGCCTQRGALYVIVEFAPHGNLRDFLKSHRPHGTSYSCIADY 507
Query: 309 -----------------------GSLVDFLKTPSGIK-------------LTINKLLDMA 332
G+ + F+ S + LT L+ A
Sbjct: 506 EQPVITSSSSSFSHPNSASSSAQGTSLGFIPGTSTVSFSTGSHRQDMLKMLTPKDLISYA 327
Query: 333 AQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTARE-GAKFPI 391
Q+A GM ++ + IHRDL A N+LV++ KIADFGL R ++ +Y + + P+
Sbjct: 326 YQVARGMEYLASKQCIHRDLAARNVLVAEEYVLKIADFGLTRNLQQFDYYRKTTDGRLPV 147
Query: 392 KWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGM 431
KW APEA+ +T KSDVWS+G+LL EI T G PYP +
Sbjct: 146 KWMAPEALFDRKYTSKSDVWSYGVLLWEIFTLGGNPYPSV 27
>18996
Length = 491
Score = 107 bits (268), Expect = 7e-24, Method: Compositional matrix adjust.
Identities = 65/158 (41%), Positives = 87/158 (55%), Gaps = 10/158 (6%)
Frame = +2
Query: 348 IHRDLRAANILVSDTLSCKIADFGLARLIE-DNEYTAREGAKFPIKWTAPEAINYGTFTI 406
IHRDL A NILV D KI+DFGLA+ D Y PIKW +PEAI F+
Sbjct: 2 IHRDLAARNILV-DRSCVKISDFGLAQFANADGYYYGISQRDIPIKWYSPEAIETCKFSS 178
Query: 407 KSDVWSFGILLTEIVTHGRIP--YPG--MTNPEVIQNLERGYRMVRPDNCPEELY-QLMR 461
SDVWS+G+ L E+ + G IP PG +T E + L +G R+ +P+ C + +Y +LMR
Sbjct: 179 YSDVWSYGVTLFEMFSRGEIPNLLPGHDLTQEEFLNRLRKGERLPKPELCSDFVYSELMR 358
Query: 462 LCWKERPEDRPTFDYLRSVLE----DFFTATEGQYQPQ 495
CW E P+ RPTF + ++ D + G Q Q
Sbjct: 359 PCWHEMPKSRPTFHQIIQIIAREMGDNISGXAGSTQQQ 472
>17637
Length = 447
Score = 105 bits (262), Expect = 4e-23, Method: Compositional matrix adjust.
Identities = 50/132 (37%), Positives = 77/132 (58%), Gaps = 1/132 (0%)
Frame = +1
Query: 356 NILVSDTLSCKIADFGLARLIEDNEYTAR-EGAKFPIKWTAPEAINYGTFTIKSDVWSFG 414
N ++ D L K+ D L+R + +Y +G PIKW + EA+ + SDVWSFG
Sbjct: 1 NCVIDDQLRVKLTDSALSRDLFSGDYNCLGDGEYRPIKWLSLEALQKSHYNEGSDVWSFG 180
Query: 415 ILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDNCPEELYQLMRLCWKERPEDRPTF 474
+L+ E+ T G++PY + E+ L+ GYR+ +P NCP+EL+ +M CW P +RP+F
Sbjct: 181 VLMWEMCTLGKLPYAEIDPYEMEHYLKDGYRLAQPFNCPDELFTIMAYCWASMPAERPSF 360
Query: 475 DYLRSVLEDFFT 486
L+ L +F T
Sbjct: 361 SQLQICLSEFHT 396
>22005
Length = 873
Score = 84.0 bits (206), Expect(2) = 6e-23, Method: Compositional matrix adjust.
Identities = 61/194 (31%), Positives = 93/194 (47%), Gaps = 44/194 (22%)
Frame = +1
Query: 272 FLAEANLMKQLQHQRLVRLYAVVT-QEPIYIITEYMENGSLVDFLK--TPSGIKLTI--- 325
F EA+LM H +V+L V +P+ ++ E+M G L DFL+ +P L +
Sbjct: 151 FEREASLMADFDHPNIVKLLGVCAIGKPMCLLFEFMSKGDLNDFLRLCSPENYNLPVSRS 330
Query: 326 -NKLLDM------------------------------------AAQIAEGMAFIEERNYI 348
N ++D+ + QI+ GMA++ +++Y+
Sbjct: 331 QNLVVDLEDGLRVEVEAEECEKDTQSEDRDCSGMLXTKDQLYISQQISAGMAYLAQKDYV 510
Query: 349 HRDLRAANILVSDTLSCKIADFGLARLIED-NEYTAREGAKFPIKWTAPEAINYGTFTIK 407
HRDL A + S T I+DFGLAR + + Y E PI+W EAI Y F+ +
Sbjct: 511 HRDL-ATRTVXSRTT*S*ISDFGLARSVHSVDYYRGSEQDAIPIRWMPLEAILYSKFSTQ 687
Query: 408 SDVWSFGILLTEIV 421
SDVWSFG++L EI+
Sbjct: 688 SDVWSFGVVLWEIL 729
Score = 42.0 bits (97), Expect(2) = 6e-23, Method: Compositional matrix adjust.
Identities = 16/42 (38%), Positives = 28/42 (66%)
Frame = +3
Query: 427 PYPGMTNPEVIQNLERGYRMVRPDNCPEELYQLMRLCWKERP 468
PY G+T+ EV+ ++ G + +P P ++Y+LM+ CW+ RP
Sbjct: 744 PYYGLTHEEVVNYVKAGKILEQPTKTPHQVYELMKQCWQRRP 869
>08294
Length = 1849
Score = 104 bits (259), Expect = 9e-23, Method: Compositional matrix adjust.
Identities = 58/198 (29%), Positives = 100/198 (50%), Gaps = 13/198 (6%)
Frame = +2
Query: 297 EPIYIITEYMENGSLVDFL-------------KTPSGIKLTINKLLDMAAQIAEGMAFIE 343
EP ++ITEY + G L FL + P+ L +++ L M Q+A GM +
Sbjct: 926 EPHFLITEYCDWGDLKQFLLATRNDNGRGRGTRVPA---LALSQKLGMGQQVAAGMEALS 1096
Query: 344 ERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGT 403
+ +H DL A N+L++ + K+A L+ + +EY P++W PE + +
Sbjct: 1097 NQGLVHGDLAARNVLLTSRMQLKVARPALSGDVYASEYYPLHQRLVPLRWLPPEGVLEDS 1276
Query: 404 FTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDNCPEELYQLMRLC 463
T DVW+FG+ L E++ +PY M++ EV+++L+ + + P L L++ C
Sbjct: 1277 ATTCGDVWAFGVFLWEVLQLADLPYRLMSDEEVLRSLQHSQAALDSPDAPPALLSLLQRC 1456
Query: 464 WKERPEDRPTFDYLRSVL 481
++P RP F + SVL
Sbjct: 1457 TAQQPSQRPPFSEICSVL 1510
>14477
Length = 493
Score = 94.0 bits (232), Expect = 1e-19, Method: Composition-based stats.
Identities = 54/158 (34%), Positives = 87/158 (55%), Gaps = 8/158 (5%)
Frame = -1
Query: 237 RLGAGQFGEVWMGYY---NGHTKVAVKSLKQGSMSPDA---FLAEANLMKQLQHQRLVRL 290
+LGAG FG V G + VA+K LK + P + EA +MK++ H +VRL
Sbjct: 469 KLGAGNFGSVMKGVCRLDDREIPVAIKVLKNADLDPSVQSELIKEAEVMKKMDHMHIVRL 290
Query: 291 YAVVTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHR 350
+ E + ++ E + G L FL P L + +L++ Q+++GM ++E ++HR
Sbjct: 289 IGLCEGETMMLVLELAKLGPLNKFL--PKNKHLPLWNILELMWQVSQGMEYLEANKFVHR 116
Query: 351 DLRAANILVSDTLSCKIADFGLARLI--EDNEYTAREG 386
DL A NIL+ D KI+DFG+++ + E+N Y A+E
Sbjct: 115 DLAARNILLCDEHFAKISDFGMSKTLSRENNYYMAQEA 2
>01718
Length = 959
Score = 91.3 bits (225), Expect = 9e-19, Method: Compositional matrix adjust.
Identities = 70/252 (27%), Positives = 120/252 (47%), Gaps = 13/252 (5%)
Frame = +3
Query: 234 LVERLGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPDAFLAEANLMKQLQHQRLVRLYAV 293
+ E++GAG F EV+ + +V + + + L E L+ +LQH ++R V
Sbjct: 159 ICEKIGAGFFSEVFKVTHRITGQVMALKMNTMTSNRHNMLREVQLLNRLQHANILRFMGV 338
Query: 294 VTQE-PIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDL 352
E ++ +TEY+ +G+L L+ +L + + + +A G+ ++ +IHRDL
Sbjct: 339 CVHEGQLHALTEYIPSGNLEQLLEKKDE-ELPWTQRIQLTLGLARGLDYLHSTRFIHRDL 515
Query: 353 RAANILV----SDTLSCKIADFGLARLIE---DNEYTAREGAKFPIKWTAPEAINYGTFT 405
+ NIL+ + IADFGLA I D E G+ + W APE +N +
Sbjct: 516 TSKNILIRREDNHGYHAVIADFGLATKIPDPLDKEKLPTVGSPY---WMAPEVLNGHFYN 686
Query: 406 IKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLER-GYRMVRPDN----CPEELYQLM 460
++D++S GI++ EI RIP +P+++ + G V CP + QL
Sbjct: 687 ERADLFSVGIIMCEIT--ARIP----ADPDIMPRMNNFGVDYVALSEMISYCPLDYLQLA 848
Query: 461 RLCWKERPEDRP 472
C + P+ RP
Sbjct: 849 FKCCQVDPQKRP 884
>19301
Length = 712
Score = 86.3 bits (212), Expect = 3e-17, Method: Compositional matrix adjust.
Identities = 52/153 (33%), Positives = 84/153 (54%), Gaps = 1/153 (0%)
Frame = +2
Query: 222 EDEWEVPRETLKLVERLGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPDAFLAEANLMKQ 281
+D+WE+P E++ +E LG+G G V++G +VAVK ++ D + +++
Sbjct: 281 QDDWEIPFESITDLEWLGSGAQGAVFLGKLCAE-EVAVKKVR------DIKETDIRNLRK 439
Query: 282 LQHQRLVRLYAVVTQEPIY-IITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMA 340
L H ++ V TQ P Y II EY G L + L+ G ++ +LD + QIA GM
Sbjct: 440 LNHPNIISFKGVCTQAPCYCIIMEYCPYGQLYEVLR--DGKEIPPALVLDWSKQIASGMN 613
Query: 341 FIEERNYIHRDLRAANILVSDTLSCKIADFGLA 373
++ IHRDL++ N+LV+ KI+DFG +
Sbjct: 614 YLHSHKIIHRDLKSPNVLVAKNDVVKISDFGTS 712
>13305
Length = 549
Score = 84.3 bits (207), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 37/89 (41%), Positives = 52/89 (58%)
Frame = +2
Query: 386 GAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYR 445
+ PI+W A E++ T+T +SDVWSFG++L EI T G PY ++ L+ GYR
Sbjct: 2 STRVPIRWMAVESLFNNTYTTQSDVWSFGVVLWEIFTLGGTPYSSTDTQQLFAFLKDGYR 181
Query: 446 MVRPDNCPEELYQLMRLCWKERPEDRPTF 474
+ RP C + Y +M CW E + RPTF
Sbjct: 182 LKRPKLCDQNTYAMMLQCWNENAQRRPTF 268
>13592
Length = 980
Score = 77.8 bits (190), Expect = 9e-15, Method: Compositional matrix adjust.
Identities = 60/252 (23%), Positives = 123/252 (48%), Gaps = 17/252 (6%)
Frame = +2
Query: 237 RLGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPDAFLAEANLMKQLQ------HQRLVRL 290
++G G+FG+V+ N ++ ++K+ ++ P A N+ ++L+ H+ LVR
Sbjct: 5 KIGQGRFGKVYTAVNNNTGELM--AMKEIAIQPGETRALKNVAEELKILEGIKHKNLVRY 178
Query: 291 YAV-VTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIH 349
Y + V +E + I E G+L ++ G+ +++ AQ+ G+A + + +H
Sbjct: 179 YGIEVHREELLIFMELCSEGTLESLVELTGGLPEALSR--RFTAQLLSGVAELHKHGIVH 352
Query: 350 RDLRAANI-LVSDTLSCKIADFGLARLIEDNE--------YTAREGAKFPIKWTAPEAIN 400
RD++ ANI LV + S K+ DFG A I+ + Y + P +T +
Sbjct: 353 RDIKTANIFLVDGSNSLKLGDFGSAVKIQAHTTVPGELQGYVGTQAYMAPEVFTKTNSDG 532
Query: 401 YGTFTIKSDVWSFGILLTEIVTHGRIPYPGM-TNPEVIQNLERGYRMVRPDNCPEELYQL 459
+G +D+WS G ++ E+ + G+ P+ +N +++ + G + P++ +E +
Sbjct: 533 HGRL---ADIWSVGCVVVEMAS-GKRPWAQFDSNFQIMFKVGMGEKPQAPESLSQEGHDF 700
Query: 460 MRLCWKERPEDR 471
+ C + P+ R
Sbjct: 701 IDHCLQHDPKQR 736
>18921
Length = 697
Score = 77.4 bits (189), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 51/196 (26%), Positives = 96/196 (48%), Gaps = 3/196 (1%)
Frame = +2
Query: 228 PRETLKLVERLGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPDA--FLAEANLMKQLQHQ 285
P + ++ +LG G +G V+ + +V ++KQ + D + E ++M+Q +
Sbjct: 23 PEDVFDILGKLGEGSYGSVFKSLHKETGQVL--AIKQVPVDTDLQEIIKEISIMQQCDSK 196
Query: 286 RLVRLY-AVVTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEE 344
+V+ Y + ++I+ EY GS+ D ++ + L ++ + +G+ ++
Sbjct: 197 YIVKYYGSYFKNTDLWIVMEYCGAGSVSDIMRLRNK-TLVEREIATILYYTLKGLXYLHS 373
Query: 345 RNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTF 404
R IHRD++A NIL+++ K+ADFG+A + D P W APE I +
Sbjct: 374 RRKIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTPY-WMAPEVIQEIGY 550
Query: 405 TIKSDVWSFGILLTEI 420
+D+WS GI E+
Sbjct: 551 DCVADIWSLGITALEM 598
>12721
Length = 821
Score = 77.4 bits (189), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 46/196 (23%), Positives = 94/196 (47%), Gaps = 2/196 (1%)
Frame = +1
Query: 228 PRETLKLVERLGAGQFGEVWMGYYNGHTKVAVKSLK-QGSMSPDAFLAEANLMKQLQHQR 286
PR L ++G G G V + ++AVK + + + E +M+ H
Sbjct: 82 PRTFLDDFMKIGEGSTGIVCIATSRDGRQMAVKKMDLRKQQRRELLFNEVVVMRDYHHPN 261
Query: 287 LVRLY-AVVTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEER 345
+V +Y + + + ++++ E+ME G+L D + + ++ ++ + + +AF+
Sbjct: 262 IVEMYNSYLVNDELWVVMEFMEGGALTDIV---TNNRMDEVQIATVCRACLKALAFLHAN 432
Query: 346 NYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFT 405
IHRD+++ +IL+S K+ DFG + + + P W APE I+ +
Sbjct: 433 GVIHRDIKSDSILLSHDGKVKLXDFGFCAQVTQDLQKRKSLVGTPY-WMAPEVISRLPYG 609
Query: 406 IKSDVWSFGILLTEIV 421
+ D+WS GI++ E++
Sbjct: 610 PEVDIWSLGIMVMEMI 657
>07833
Length = 1504
Score = 77.4 bits (189), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 60/220 (27%), Positives = 108/220 (49%), Gaps = 9/220 (4%)
Frame = -3
Query: 272 FLAEANLMKQLQHQRLVRLYAVVTQEP-IYIITEYMENGSLVDFLKTPSGIKLTINKLLD 330
F+ E ++ H ++ + A Q P + +I+++M GSL + L SGI + N+ L
Sbjct: 1478 FMEEFPRLRIFNHPNVLPVLACCNQPPNLVLISQFMPFGSLYNTLHGESGIVVDQNQSLR 1299
Query: 331 MAAQIAEGMAFIE--ERNYIHRDLRAANILVSDTLSCKI--ADFGLARLIEDNEYTAREG 386
A IA GM F+ E + L + ++++ + L+ +I AD+ + +G
Sbjct: 1298 FAMDIARGMEFLHSMEPTIPNFLLTSKHVMIDEDLTARINMADYCFS--------FHEKG 1143
Query: 387 AKFPIKWTAPEAINY---GTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEV-IQNLER 442
+ W APEA+ T +D+WSF IL+ E+ T +P+ +++ EV ++
Sbjct: 1142 KVYSPAWMAPEALQRRPDDINTRAADMWSFAILMWELETR-EVPFAELSSMEVGMKVALE 966
Query: 443 GYRMVRPDNCPEELYQLMRLCWKERPEDRPTFDYLRSVLE 482
G R+ P + +L+++C E P RP FD + +LE
Sbjct: 965 GLRISIPPGISLHMSRLIKICMNEEPGKRPRFDMIIPILE 846
>01060
Length = 1800
Score = 76.3 bits (186), Expect = 3e-14, Method: Compositional matrix adjust.
Identities = 58/230 (25%), Positives = 112/230 (48%), Gaps = 6/230 (2%)
Frame = +1
Query: 224 EWEVPRETLKLVERLGAGQFGEVWMGYYNGH-TKVAVKSLK-QGSMS--PDAFLAEANLM 279
++E L +++G G +G V+ + K+A+K ++ +GS P + + E ++
Sbjct: 55 DFETALSDLTDFQKIGEGTYGVVYKCRHRATGRKLAMKKIRLRGSEDGVPSSAIREIAML 234
Query: 280 KQLQHQRLVRLYAVVTQ-EPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEG 338
++L+H +V L V+ + E ++++ E++ + K P G+ L + QI G
Sbjct: 235 RELRHTNIVCLEDVIMEDERLFLVFEFLSMDLKMYIDKFPEGVVLDRRLVKSYVFQIVTG 414
Query: 339 MAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEA 398
+ F +R +HRDL+ N+L++ T + KIADFG+AR A + + APE
Sbjct: 415 IXFCHQRRIVHRDLKPQNLLINHTGAIKIADFGMARTFA-LPVRAYTHEVVTLWYRAPEI 591
Query: 399 I-NYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMV 447
+ ++ DVWS G + +++ I P I L + +R++
Sbjct: 592 LMGASKYSTPVDVWSIGTIFADML----IRTPIFKGDSEIDQLFKIFRII 729
>29581
Length = 1278
Score = 75.5 bits (184), Expect = 4e-14, Method: Compositional matrix adjust.
Identities = 53/187 (28%), Positives = 98/187 (52%), Gaps = 10/187 (5%)
Frame = -2
Query: 262 LKQGSMSPDAFLAEANLMKQLQHQRLVRLYAVV---TQEPIYIITEYMEN--GSLVDFLK 316
L++ +SP + + L+HQ +V+L VV + + ++++ EY E SL+D +
Sbjct: 1244 LERDMVSPSVVCVRSTFLLNLRHQNIVQLQEVVVGKSLDSLFLVMEYCEQDLASLLDNMP 1065
Query: 317 TPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLI 376
P + +++ + Q+ +G+ ++ E IHRDL+ +N+L++D KIADFGLAR
Sbjct: 1064 AP----FSESQVKCIVLQLLKGLRYLHEAFIIHRDLKVSNLLMTDKGCVKIADFGLAR-- 903
Query: 377 EDNEYTAREGAKFP----IKWTAPEAI-NYGTFTIKSDVWSFGILLTEIVTHGRIPYPGM 431
Y + P + + APE + T + D+WS G +L E++ H + PG
Sbjct: 902 ---NYGKPQKPMTPKVVTLWYRAPELLFGSKTHSTAIDMWSAGCILGELLGHKPL-MPGR 735
Query: 432 TNPEVIQ 438
++ + I+
Sbjct: 734 SDLQQIE 714
>17253
Length = 483
Score = 72.8 bits (177), Expect = 3e-13, Method: Composition-based stats.
Identities = 45/153 (29%), Positives = 75/153 (49%), Gaps = 16/153 (10%)
Frame = -1
Query: 257 VAVKSLKQGSMSPDA--FLAEANLMKQL-QHQRLVRLYAVVT-QEPIYIITEYMENGSLV 312
VAVK+ + + + FL E ++M++L +H +V T +P I+ E+ +G L+
Sbjct: 459 VAVKTHNEAATDAEKSEFLRELSIMRKLPRHPNVVSFMGCCTMSDPALILMEFCCHGDLL 280
Query: 313 DFLK----------TPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDT 362
FL+ T + LT A +A GMA + +HRD+ A N+L+S+
Sbjct: 279 SFLRKRRPDRTVFLTSTANDLTARDFFSFALHVARGMAHVANNKIVHRDVAARNVLISER 100
Query: 363 LSCKIADFGLARLIEDNE--YTAREGAKFPIKW 393
CK++DFGL+R + D Y P++W
Sbjct: 99 NVCKVSDFGLSRRVGDQNDVYEIVSRRPLPLRW 1
>14126
Length = 1265
Score = 72.8 bits (177), Expect = 3e-13, Method: Compositional matrix adjust.
Identities = 54/204 (26%), Positives = 98/204 (48%), Gaps = 16/204 (7%)
Frame = +3
Query: 235 VERLGAGQFGEVW-------MGYYNGHTKVAVKSLKQGSMSPDAFLAEANLMKQLQ---H 284
V +G G +G V+ G + ++ + + ++G P + E +++KQL+ H
Sbjct: 204 VAVIGNGAYGTVYKARDLRNQGEFVAMKRIRLNNTEEGM--PMMAIREISMLKQLEQYEH 377
Query: 285 QRLVRLYAV----VTQEPIYI--ITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEG 338
+VRL V +T I + + EY+E+ K PS L +++ D+ Q+ G
Sbjct: 378 PNVVRLLDVSHNTITDREIRLNLVFEYIEHDLATYLAKCPSP-GLGPDRIKDLMLQLLNG 554
Query: 339 MAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEA 398
+ F+ +HRDL+ N+L+S K+ADFGLAR+ + + A + + +PE
Sbjct: 555 VDFLHSNRIVHRDLKPQNLLISKDGRLKLADFGLARIY--SFHMALTTVVVTLWYRSPEV 728
Query: 399 INYGTFTIKSDVWSFGILLTEIVT 422
+ + D+WS G + E+ T
Sbjct: 729 LMQAEYGTSVDIWSCGCIFAELFT 800
>01707
Length = 757
Score = 72.0 bits (175), Expect = 5e-13, Method: Compositional matrix adjust.
Identities = 56/212 (26%), Positives = 109/212 (51%), Gaps = 8/212 (3%)
Frame = +1
Query: 230 ETLKLVERLGAGQFGEVWMGYYNGHTK-VAVKSLKQGSMSP---DAFLAEANLMKQLQHQ 285
E + + ++G G +G V+ ++ VA+K + P + E ++KQL+H
Sbjct: 64 EKYEKIGKIGEGSYGVVFKCRNKETSQLVAIKKFVESEDDPLIKKIAMREIRMLKQLKHP 243
Query: 286 RLVRLYAVVTQEP-IYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEE 344
LVRL V ++ ++++ +Y+++ L + + P G+ + K + +A + F +
Sbjct: 244 NLVRLIEVFRRKKRLHLVFDYVDHTLLNELDRYPRGLPEPMVKRIIYQTLLA--VNFCHQ 417
Query: 345 RNYIHRDLRAANILVSDTLSCKIADFGLARLIE--DNEYTAREGAKFPIKWTAPEAINYG 402
N IHRD++ NIL++ K+ DFG AR++ +EYT ++ + APE +
Sbjct: 418 YNTIHRDVKPENILITRQGQVKLCDFGFARILTGPGDEYTDYVATRW---YRAPELLVGD 588
Query: 403 T-FTIKSDVWSFGILLTEIVTHGRIPYPGMTN 433
T + DVW+ G + E++T G+ +PG ++
Sbjct: 589 TQYGPPVDVWAIGCVFAELLT-GQALWPGRSD 681
>01756
Length = 1858
Score = 68.6 bits (166), Expect = 6e-12, Method: Compositional matrix adjust.
Identities = 61/232 (26%), Positives = 102/232 (43%), Gaps = 33/232 (14%)
Frame = -3
Query: 228 PRETLKL-----------VERLGAGQFGEVWMGYYN------GHTKVAVKSLKQGSMSPD 270
P ETLK + ++G G FGEV+ KV + + K+G P
Sbjct: 1781 PYETLKFPFCDEDAKYEKLAKIGQGTFGEVFKARCKKTKQVVAMKKVLMDNEKEGF--PI 1608
Query: 271 AFLAEANLMKQLQHQRLVRLYAVVTQEP---------IYIITEYMENGSLVDFLKTPSGI 321
L E +++ L H+ +V L + + + Y++ E+ E+ L L S +
Sbjct: 1607 TALREIKILQLLNHENVVDLIEICSTKATSANRYKSMFYLVFEFCEH-DLAGLLSNMSVV 1431
Query: 322 KLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLAR-----LI 376
+ ++ ++ Q+ G+ +I +HRD++AANIL++ K+ADFGLAR L
Sbjct: 1430 -FNLPEIKEVMKQLMNGLYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLR 1254
Query: 377 EDNEYTAREGAKFPIKWTAPEAINYG--TFTIKSDVWSFGILLTEIVTHGRI 426
+ N YT R W P + G ++ D W G ++ E+ T I
Sbjct: 1253 QPNRYTNR----VVTLWYRPPELLLGDRNYSTAIDQWGAGCIMAEMWTRNPI 1110
>00300
Length = 2318
Score = 68.2 bits (165), Expect = 6e-12, Method: Compositional matrix adjust.
Identities = 59/263 (22%), Positives = 117/263 (44%), Gaps = 13/263 (4%)
Frame = -1
Query: 237 RLGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPD------AFLAEANLMKQLQHQRLVRL 290
++G GQFG+V+ + + +LK+ P+ E + + +QH+ LV+
Sbjct: 1637 KIGEGQFGKVYTAV--NMSTGELMALKEMKFQPNDLQQLREMCDEIKIFEGIQHENLVKY 1464
Query: 291 YAV-VTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIH 349
Y V V ++ + + EY + G++ + K + L + +I + + E + +H
Sbjct: 1463 YGVEVHKDEMLMFMEYCDTGTIEEAAK----MGLPEYLIRRYTREIVLAVNHLHENSIVH 1296
Query: 350 RDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKF--PIKWTAPEAI---NYGTF 404
RD++ ANI ++ K+ DFG + ++ + E + APE + G +
Sbjct: 1295 RDIKGANIFLTSNGHVKLGDFGCSVKLKSHTTMPGEFHNLVGTTAYMAPEVFTQNDQGGY 1116
Query: 405 TIKSDVWSFGILLTEIVTHGRIPYPGMTNP-EVIQNLERGYRMVRPDNCPEELYQLMRLC 463
+D+WS G ++ E+ T G+ P+ + N +++ + G++ PD+ E + L
Sbjct: 1115 GRAADIWSLGCVVIEMAT-GKRPWHDLDNNYQIMYKVGIGHKPAVPDSLSVEGKHFLDLI 939
Query: 464 WKERPEDRPTFDYLRSVLEDFFT 486
P R L L+ FT
Sbjct: 938 MCHDPAQRALASQL---LDHTFT 879
>00715
Length = 1788
Score = 67.4 bits (163), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 49/172 (28%), Positives = 82/172 (47%), Gaps = 27/172 (15%)
Frame = +1
Query: 329 LDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLI------------ 376
L +A Q+A G+ ++ N +H DL+ AN L++ L +IADFG +
Sbjct: 247 LSLALQMARGLHYLHSINIVHLDLKPANCLLTRDLKLRIADFGCCHQLTPTGLDMGEREG 426
Query: 377 ----EDNEYTAREGA-----KFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIP 427
+ E T +GA + + APE + +++SDV+S GI L ++ T + P
Sbjct: 427 GMAGNELELTPVQGAWKNELAGTLAYRAPELLKGLQPSVRSDVYSLGITLWQMCTR-QGP 603
Query: 428 YPGMTNPEVI-QNLERGYRMVRPDNCPEELYQLM-----RLCWKERPEDRPT 473
Y G+ V+ Q + + R P + ++ +++M CW R EDRPT
Sbjct: 604 YEGVPAHAVVYQVVSKDLRPCPPPSTEDDPFEVMFRDLYTQCWARRVEDRPT 759
>01966
Length = 1735
Score = 65.1 bits (157), Expect = 6e-11, Method: Compositional matrix adjust.
Identities = 38/123 (30%), Positives = 71/123 (57%), Gaps = 4/123 (3%)
Frame = -1
Query: 256 KVAVKSLK-QGSMS--PDAFLAEANLMKQLQHQRLVRLYAVVTQ-EPIYIITEYMENGSL 311
K+A+K ++ +GS P + + E ++++L+H +V L V+ + E ++++ E++
Sbjct: 1630 KLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTNIVCLEDVIMEDERLFLVFEFLSMDLK 1451
Query: 312 VDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFG 371
+ K P G+ L + QI G+ F +R +HRDL+ N+L++ T + KIADFG
Sbjct: 1450 MYIDKFPEGVVLDRRLVKSYVFQIVTGINFCHQRRIVHRDLKPQNLLINHTGAIKIADFG 1271
Query: 372 LAR 374
+AR
Sbjct: 1270 MAR 1262
>14420
Length = 528
Score = 65.1 bits (157), Expect = 7e-11, Method: Compositional matrix adjust.
Identities = 39/162 (24%), Positives = 80/162 (49%), Gaps = 3/162 (1%)
Frame = +2
Query: 270 DAFLAEANLMKQLQHQRLVR-LYAVVTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKL 328
+ + E +M++ Q+ +V L + + E ++++ E++ GSL D + + ++
Sbjct: 35 ELIINEILVMRENQNPNIVNYLDSYLVGEELWVVMEFLAGGSLTDVVTETC---MDEGQI 205
Query: 329 LDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLI--EDNEYTAREG 386
+ + + + F+ E IHRD+++ NIL+ S K+ DFG + E ++ + G
Sbjct: 206 AAVCRECLQALEFLHENQVIHRDIKSDNILLGMDGSVKLTDFGFCAQLSPEQSKRSTMVG 385
Query: 387 AKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPY 428
+ W APE + + D+WS G++ E++ G PY
Sbjct: 386 TPY---WMAPEVVTRKQYGPTVDIWSLGVMCIEMI-EGEPPY 499
>27546
Length = 426
Score = 63.9 bits (154), Expect = 1e-10, Method: Composition-based stats.
Identities = 33/108 (30%), Positives = 59/108 (54%), Gaps = 1/108 (0%)
Frame = -1
Query: 272 FLAEANLMKQLQHQRLVRLYAVVTQEP-IYIITEYMENGSLVDFLKTPSGIKLTINKLLD 330
F E ++ +L H ++++++++ + P I+I Y E G ++ +K I K+
Sbjct: 339 FPRELEILTRLDHPNIIQIHSILQRGPKIFIFMRYAEKGDMLSHIKKTGPIDEAQTKVWF 160
Query: 331 MAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIED 378
Q+A+ + ++ + HRDL+ NIL+S L+ KIADFG AR D
Sbjct: 159 F--QMAKALQYLHSHDIAHRDLKCENILLSKRLNVKIADFGFARYCRD 22
>18484
Length = 635
Score = 63.5 bits (153), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 39/140 (27%), Positives = 70/140 (50%)
Frame = +1
Query: 332 AAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPI 391
AA+IA G+ F+ ++ I+RDL+ N+++ KIADFG+ + + T R P
Sbjct: 61 AAEIAVGLFFLHDQGIIYRDLKLDNVMLDSEGHIKIADFGMCKEGMTGDATTRTFCGTP- 237
Query: 392 KWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDN 451
+ APE + Y ++ D W++G+LL E++ G+ P+ G E+ ++ + + P
Sbjct: 238 DYIAPEIVLYQPYSKSVDWWAYGVLLFEMLA-GQPPFDGEDEDELFSSI-TDHNVSYPKA 411
Query: 452 CPEELYQLMRLCWKERPEDR 471
E L + + P R
Sbjct: 412 MSREAVSLCKGLLMKNPTKR 471
>12672
Length = 773
Score = 63.2 bits (152), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 43/166 (25%), Positives = 72/166 (43%), Gaps = 17/166 (10%)
Frame = +3
Query: 336 AEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPI---K 392
A G+ ++ + ++HRD++ ANIL+ + K+ DF E + A I
Sbjct: 21 ASGIQYLNDNGHVHRDIKTANILLDSEYTAKVGDFATVVSAPSGEGKTVQNASVVIGTAA 200
Query: 393 WTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIP--------------YPGMTNPEVIQ 438
+ APEAI++ T K D +SFG++L E++T G + + PE I
Sbjct: 201 YLAPEAIHFDVST-KLDSYSFGVVLLEVIT-GLVAQDYSREERTLSSHIMENVEEPEEIH 374
Query: 439 NLERGYRMVRPDNCPEELYQLMRLCWKERPEDRPTFDYLRSVLEDF 484
+ PD ++LY + C + RP +R LE+
Sbjct: 375 DFVDQSAGTWPDGAVDKLYDISMRCLNLSKKQRPNVKDIRPELEEL 512
>04591
Length = 1117
Score = 60.8 bits (146), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 42/166 (25%), Positives = 82/166 (49%), Gaps = 14/166 (8%)
Frame = -2
Query: 269 PDAFLAEANLMKQLQHQRLVRLYAVVTQEP---------IYIITEYMEN--GSLVDFLKT 317
P L E +++QL+H+ +V+L + + Y+I EY + L++ L+
Sbjct: 1089 PITALREIKILQQLEHENVVQLQEICHTQAGPYNRYKSTFYLIFEYCDYDLAGLLNNLR- 913
Query: 318 PSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLAR-LI 376
+K ++ ++ +Q+ G+ +I + +HRD++AANIL++ K+ADFGL+R +
Sbjct: 912 ---VKFSLADKKNLMSQLLNGLFYIHTKQILHRDIKAANILLTRDGVLKLADFGLSRPWV 742
Query: 377 EDNEYTAREGAKFPIKWTAPEAINYG--TFTIKSDVWSFGILLTEI 420
+ T R W P + G + + D+W G ++ E+
Sbjct: 741 KSKRLTNR----VVTLWYRPPELLLGEREYGPEIDMWGVGCIMAEM 616
>25550
Length = 941
Score = 60.5 bits (145), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 28/63 (44%), Positives = 39/63 (61%)
Frame = +3
Query: 426 IPYPGMTNPEVIQNLERGYRMVRPDNCPEELYQLMRLCWKERPEDRPTFDYLRSVLEDFF 485
+ YPG+ EV LERGYRM RP P ++Y LM CW+ P++RPTF + +LE+ F
Sbjct: 36 VXYPGVDLTEVYHLLERGYRMERPQGTPADVYILMLKCWQWDPKERPTFKEIHYLLENMF 215
Query: 486 TAT 488
+
Sbjct: 216 EKS 224
>07836
Length = 1478
Score = 59.3 bits (142), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 61/220 (27%), Positives = 105/220 (47%), Gaps = 45/220 (20%)
Frame = -1
Query: 299 IYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNY--------IHR 350
+++IT+Y ENGSL D+L + L +++L +A G+A + + HR
Sbjct: 1328 LFLITDYHENGSLHDYLLSRV---LDSSEMLALAHSAICGLAHLHIEIFGTRGKPAIAHR 1158
Query: 351 DLRAANILVSDTLSCKIADFGLA-RLI-EDNEYTA----REGAKFPIKWTAPEAI----- 399
D+++ NILV +C IAD GLA R I E NE R+G K ++ APE +
Sbjct: 1157 DIKSKNILVKKNGTCCIADLGLAVRYISESNEVDVAPNPRQGTK---RYMAPEVLEMLLN 987
Query: 400 --NYGTFTIKSDVWSFGILLTEI----VTHG-----RIPY-------PGMTNPEVIQNLE 441
N+ F ++D+++FG+++ EI V G ++P+ P + ++ +++
Sbjct: 986 VKNFDAFK-QADMYAFGLVMWEIARCCVIGGVAEEYQVPFYNCLPHDPSFEDVRLVVSVD 810
Query: 442 RGYRMVRPDN--------CPEELYQLMRLCWKERPEDRPT 473
+ VRPD + + ++M CW P R T
Sbjct: 809 K----VRPDIPLRWQEDPIMKVMVKVMCECWSGNPAARLT 702
>31885
Length = 529
Score = 57.0 bits (136), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 41/169 (24%), Positives = 76/169 (44%), Gaps = 8/169 (4%)
Frame = -2
Query: 276 ANLMKQLQHQRLVRL-YAVVTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQ 334
+++ +L H LV L YA +E ++++ + G L ++ + K Q
Sbjct: 519 VDMLTRLDHPFLVNLWYAFQDEEDLFMVVDLFLGGDLRYHMQQEVSFREDCVKF--YLCQ 346
Query: 335 IAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWT 394
+A + ++ + +HRD++ NIL+ + C + DF +A +ED+E P +
Sbjct: 345 LALVLDYLRSQKIVHRDIKPDNILLDEQGHCHVTDFNIATQLEDDELATSTSGTRP--YM 172
Query: 395 APEAINYGT-------FTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEV 436
APE YG + D WS G+ L E++ R P+ +N +
Sbjct: 171 APEV--YGVAINERRGYGFPVDWWSLGVSLFELLKKRR-PFSVHSNTSL 34
>17975
Length = 449
Score = 56.6 bits (135), Expect = 3e-08, Method: Composition-based stats.
Identities = 38/124 (30%), Positives = 65/124 (52%), Gaps = 6/124 (4%)
Frame = +3
Query: 256 KVAVKSL---KQGSMSPDAFLAEANLMKQLQHQRLVRLYAVV-TQEPIYIITEYMENGSL 311
KVAVK + K +S E MK +QH +VRLY V+ TQ +Y+I E + G +
Sbjct: 48 KVAVKVIDKTKLDEVSRSHLFQEVRCMKLVQHPNVVRLYEVIDTQTKLYLILELGDGGDM 227
Query: 312 VDF-LKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLS-CKIAD 369
D+ ++ G++ + K QI E +++ + + +HRDL+ N++ + K+ D
Sbjct: 228 YDYIMRHSGGLEEKLAK--RYFRQIVEAISYCHKLHVVHRDLKPENVVFFEKPGLVKLTD 401
Query: 370 FGLA 373
FG +
Sbjct: 402 FGFS 413
>13066
Length = 551
Score = 56.2 bits (134), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 42/172 (24%), Positives = 80/172 (46%), Gaps = 8/172 (4%)
Frame = +3
Query: 251 YNGHTKVAVKSLKQGSMSPDA----FLAEANLMKQLQHQRLVRLYAVVTQEPI-YIITEY 305
Y + K+A K + + D F E +L+ +L H ++++++++ + P +I +
Sbjct: 42 YGRNIKLACKIIDKEKAPVDFVEKFFPRELDLLTKLDHPYIIQIHSILQRXPKNFIFMRF 221
Query: 306 MENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSC 365
E G L+ +++ +K K+ Q+ + ++ + HRDL+ NIL+S +
Sbjct: 222 AERGDLLTYIQEVGFVKEKQAKI--WFYQMTTALNYLHSYDVAHRDLKCENILLSSHFNV 395
Query: 366 KIADFGL--ARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIK-SDVWSFG 414
K+ADFG A + E E + APE + + K +D WS G
Sbjct: 396 KLADFGFACACITESGEKYMSRTYCGSAAYAAPEIVYGAPYAPKVADAWSLG 551
>19094
Length = 898
Score = 55.5 bits (132), Expect = 5e-08, Method: Compositional matrix adjust.
Identities = 29/84 (34%), Positives = 45/84 (53%)
Frame = +1
Query: 337 EGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAP 396
+G+ ++ R IHRD++A NIL+++ K+ADFG+A + D P W AP
Sbjct: 91 KGL*YLHSRRKIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTP-YWMAP 267
Query: 397 EAINYGTFTIKSDVWSFGILLTEI 420
E I + +D+WS GI E+
Sbjct: 268 EVIQEIGYDCVADIWSLGITALEM 339
>09606
Length = 1300
Score = 55.1 bits (131), Expect = 7e-08, Method: Compositional matrix adjust.
Identities = 49/225 (21%), Positives = 88/225 (39%), Gaps = 22/225 (9%)
Frame = -3
Query: 230 ETLKLVERLGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPDAFLAEANLMKQLQHQRLVR 289
E L E LG G+ ++ G G + P+ + + H +V+
Sbjct: 1115 ENFVLYEELGKGEHSIIYKGRRKGTINFVAIHCIEKCKRPEV-TNTVRMTHDISHPNVVQ 939
Query: 290 LYA-VVTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYI 348
+ T ++++ E GSL D L + T + D + G+ +I +
Sbjct: 938 FHEWYETSNHLWLVVELCTGGSLADILAQDHHLPET--SIRDFGIHLVTGLHYIHSLGIL 765
Query: 349 HRDLRAANILVSDTLSCKIADFGLARLIEDNEYT-----AREGAKFPIK----------- 392
DLR + +L+ + K ADFGL+++ +N A G ++ I+
Sbjct: 764 FHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQWNIQSAEEMMKQVPT 585
Query: 393 -----WTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMT 432
+ APE +I SD+W+ G + E+ + G P+ G T
Sbjct: 584 SGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFS-GHPPFLGET 453
>03240
Length = 1683
Score = 54.3 bits (129), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 67/290 (23%), Positives = 123/290 (42%), Gaps = 61/290 (21%)
Frame = -3
Query: 235 VERLGAGQFGEVWMGYYNGHTKV-AVKSLKQGSM----SPDAFLAEANLMKQLQHQRLVR 289
++ LG G FGEV + N + A+K+L++ + AE +++ + ++ +V+
Sbjct: 1276 IKTLGVGAFGEVSLCRKNDTGMLYAMKTLRKSDVLKRNQVAHVKAERDILAEADNEWVVK 1097
Query: 290 LY-AVVTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLD------MAAQIAEGMAFI 342
LY + +Y + +Y+ G L+ L I++ I LD A++ + + +
Sbjct: 1096 LYYSFQDHNYLYFVMDYVPGGDLMGLL-----IRMEI---LDEPLARFYVAELVQAIESV 941
Query: 343 EERNYIHRDLRAANILVSDTLSCKIADFGLA---RLIEDNEYTAREGAKF---------- 389
+IHRD++ NIL+ K+ DFGL R +++Y R+G
Sbjct: 940 HRMGFIHRDIKPDNILIDRNGHIKLTDFGLCTGFRWTHNSKYYQRDGTHARQDSMEVKCQ 761
Query: 390 -----------PIK-------------------WTAPEAIN-YGTFTIKSDVWSFGILLT 418
P++ + APE ++ G +T D WS G++L
Sbjct: 760 LDEQCQCEILKPLERRRKREQRCLAHSLVGTPNYIAPEVLSRLGGYTSVCDWWSVGVILF 581
Query: 419 EIVTHGRIPY----PGMTNPEVIQNLERGYRMVRPDNCPEELYQL-MRLC 463
E++ G P+ P T +VI N + ++ R N + L +RLC
Sbjct: 580 EMLV-GHPPFYANTPAETQYKVI-NWKDMLKIPRESNLSQPAKDLILRLC 437
>30755
Length = 1137
Score = 51.2 bits (121), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 37/142 (26%), Positives = 69/142 (48%), Gaps = 2/142 (1%)
Frame = +2
Query: 332 AAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEY--TAREGAKF 389
A+I + ++ + I+RDL+ N+L+ K+ADFGL + ED Y T +
Sbjct: 50 GAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCK--EDITYGRTTKTFCGT 223
Query: 390 PIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRP 449
P ++ APE ++ + D W G+++ E++ GR+P+ + +V+ L + P
Sbjct: 224 P-EYLAPEVLDDNDYGRAVDWWGTGVVMYEMIC-GRLPFYNRDH-DVLFTLILVEDVKFP 394
Query: 450 DNCPEELYQLMRLCWKERPEDR 471
N +E L+ + P +R
Sbjct: 395 RNITDEAKSLLSGLLAKDPRNR 460
>21079
Length = 878
Score = 50.8 bits (120), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 38/137 (27%), Positives = 68/137 (49%), Gaps = 4/137 (2%)
Frame = +1
Query: 284 HQRLVRLY-AVVTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFI 342
H +L+ L+ A + ++ E++ G L + + + LT + QI G+ ++
Sbjct: 1 HPKLLMLWDAFEAPRTMVLVMEFVGAGELFERVIRDDFV-LTERDCVHFVRQICSGVGYM 177
Query: 343 EERNYIHRDLRAANIL-VSDTLS-CKIADFGLARLIE-DNEYTAREGAKFPIKWTAPEAI 399
++ +H DL+ N+L VSD + KI DFGLAR + + G ++ APE +
Sbjct: 178 HTQSILHLDLKPENVLCVSDNSNQIKIIDFGLARFYKPGDSLQVLFGTP---EFIAPEVV 348
Query: 400 NYGTFTIKSDVWSFGIL 416
NY +D+WS G++
Sbjct: 349 NYDEINFTTDMWSIGVI 399
>15910
Length = 1361
Score = 49.7 bits (117), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 34/114 (29%), Positives = 57/114 (50%), Gaps = 3/114 (2%)
Frame = +2
Query: 333 AQIAEGMAFIEERNYIHRDLRAANIL---VSDTLSCKIADFGLARLIEDNEYTAREGAKF 389
+ I G+ +I +HRDL+ N+L ++D K+ADFGL+R+IE E
Sbjct: 485 SDILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLADFGLSRIIEP-EVQMSTVCGT 661
Query: 390 PIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERG 443
P + APE + +T D+WS G+ + I+ G P+ E+ + + +G
Sbjct: 662 P-GYCAPEVLKGDKYTPSVDMWSVGV-IAYILLCGYEPFFAENEFEMYRKIIKG 817
>04138
Length = 800
Score = 49.3 bits (116), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 32/97 (32%), Positives = 47/97 (48%), Gaps = 7/97 (7%)
Frame = +1
Query: 337 EGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLAR-----LIEDNEYTAREGAKFPI 391
E + +I +HRD++AANIL++ K+ADFGLAR L + N YT R
Sbjct: 46 ERLYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNR----VVT 213
Query: 392 KWTAPEAINYG--TFTIKSDVWSFGILLTEIVTHGRI 426
W P + G ++ D W G ++ E+ T I
Sbjct: 214 LWYRPPELLLGDRNYSTAIDQWGAGCIMAEMWTRNPI 324
>13212
Length = 1067
Score = 49.3 bits (116), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 28/93 (30%), Positives = 48/93 (51%), Gaps = 7/93 (7%)
Frame = -1
Query: 334 QIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKF--PI 391
++ + F+ + IHRD++A N+L++ K+ADFG++ N T ++ F
Sbjct: 956 EMCMALDFLHRHHVIHRDIKAGNVLLTIDGEVKLADFGVSA---KNTQTQQKRDTFIGTP 786
Query: 392 KWTAPEAINYGT-----FTIKSDVWSFGILLTE 419
W APE + T + K+D+WS G+ L E
Sbjct: 785 YWMAPEVVLCETLKDTPYDFKADIWSLGVTLIE 687
>26711
Length = 405
Score = 47.4 bits (111), Expect = 1e-05, Method: Composition-based stats.
Identities = 33/111 (29%), Positives = 58/111 (52%), Gaps = 3/111 (2%)
Frame = -2
Query: 334 QIAEGMAFIEERNYIHRDLRAANILVS-DTL-SCKIADFGLAR-LIEDNEYTAREGAKFP 390
Q+ + + + + +H DL+ +N+L+S D L S ++ DFGLAR L E G
Sbjct: 392 QVLDILQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARKLYPPQETFLNHGTP-- 219
Query: 391 IKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLE 441
+T+PEA++ + SDVW G+ L I+ G+ P+ + E ++ +
Sbjct: 218 -GFTSPEALDVKPISTASDVWGVGV-LAYILLSGQSPFQADSATESLKKTQ 72
>35671
Length = 567
Score = 46.6 bits (109), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 18/47 (38%), Positives = 31/47 (65%)
Frame = -3
Query: 441 ERGYRMVRPDNCPEELYQLMRLCWKERPEDRPTFDYLRSVLEDFFTA 487
++G R+ +P +C +E Y++M CW E E+RPTF L V+E+ + +
Sbjct: 565 QKGNRLAKPISCTDEAYKVMLQCWTESREERPTFKKLVPVMENLYRS 425
>01392
Length = 1806
Score = 45.4 bits (106), Expect = 5e-05, Method: Compositional matrix adjust.
Identities = 34/115 (29%), Positives = 54/115 (46%), Gaps = 12/115 (10%)
Frame = -1
Query: 334 QIAEGMAFIEERNYIHRDLRAANIL---VSDTLSCKIADFGLARLIE-DNEYTAREGAKF 389
IA + F+ + HRDL+ NIL + D + KI DF LA I D + T
Sbjct: 1767 HIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGISCDGDGTKTPELLT 1588
Query: 390 PI---KWTAPEAINY-----GTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEV 436
P+ ++ APE ++ ++ + D+WS GI+L I+ G P+ G +
Sbjct: 1587 PVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILY-IMLCGYPPFYGQCGEDC 1426
>19761
Length = 473
Score = 45.1 bits (105), Expect = 7e-05, Method: Compositional matrix adjust.
Identities = 32/127 (25%), Positives = 61/127 (48%), Gaps = 4/127 (3%)
Frame = -3
Query: 334 QIAEGMAFIEERN--YIHRDLRAANILVSDTLSCKIADFGLARLIED--NEYTAREGAKF 389
Q A + ++ +HRDL+ NI V++ ++ D GLAR + + T++ G
Sbjct: 399 QTASALNYMHTHTPVILHRDLKPQNIYVTEKGDVRLGDLGLARKLTGPADFATSQVGT-- 226
Query: 390 PIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRP 449
I + +PE ++ + KSD+WS G + +I G+ M ++ + G ++ P
Sbjct: 225 -IMYLSPEILSQQPYNSKSDIWSLGCVFYDIT--GKKGSDEMGVMFLLVQVMGGRKLPLP 55
Query: 450 DNCPEEL 456
D+ +E
Sbjct: 54 DHYSQEF 34
>16708
Length = 1397
Score = 44.7 bits (104), Expect = 8e-05, Method: Compositional matrix adjust.
Identities = 35/151 (23%), Positives = 66/151 (43%), Gaps = 7/151 (4%)
Frame = -1
Query: 232 LKLVERLGAGQFGEVWMG-YYNGHTKVAVKSLKQGSMSPDAFLAEANLMKQLQHQRLVRL 290
+ +++ LG G FG+V+ + H K A+K+ S D A + ++
Sbjct: 1397 VAILQVLGKGVFGKVYEARLLSTHEKAALKTSILCHHSLDEVEALGRIEGGFYLAQMFGA 1218
Query: 291 YAVVTQEP-IYIITEYMENGSLVDFLKTPSGIKLTIN-----KLLDMAAQIAEGMAFIEE 344
+ P + I+ + E G L + ++ I + +A Q + I E
Sbjct: 1217 WVTCLPFPKMNILLHFYEMGPLCNVYAHYKNKEMPIRWSNPAMVCCIAGQXVCALEHIHE 1038
Query: 345 RNYIHRDLRAANILVSDTLSCKIADFGLARL 375
+H D++A N+LV +CK+ D+G+A+L
Sbjct: 1037 LGVVHMDVKADNVLVDAHGNCKLTDYGIAQL 945
>37602
Length = 804
Score = 44.7 bits (104), Expect = 8e-05, Method: Compositional matrix adjust.
Identities = 22/79 (27%), Positives = 43/79 (54%)
Frame = -1
Query: 292 AVVTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRD 351
+ + +E ++I EY GS+ D LT ++ + + +G+ ++ R +HRD
Sbjct: 315 SYLRREKLWIAMEYCGGGSMQDIYHVTG--PLTEPQIAFVCRETLKGLHYLHRRGKMHRD 142
Query: 352 LRAANILVSDTLSCKIADF 370
++ ANIL+++ K+ADF
Sbjct: 141 IKGANILLTEEGDVKLADF 85
>26560
Length = 398
Score = 44.3 bits (103), Expect = 1e-04, Method: Composition-based stats.
Identities = 29/98 (29%), Positives = 51/98 (52%), Gaps = 1/98 (1%)
Frame = -1
Query: 332 AAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPI 391
AA++ G+ + R ++RDL+ ANIL+ + +I+D GLA A G
Sbjct: 338 AAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGLACDFSKKRPHASVGTH--- 168
Query: 392 KWTAPEAINYG-TFTIKSDVWSFGILLTEIVTHGRIPY 428
+ APE + G ++ +D +SFG +L +++ G P+
Sbjct: 167 GYMAPEVLMKGQSYDSSADWFSFGCMLYKLLK-GHSPF 57
>27405
Length = 532
Score = 42.4 bits (98), Expect = 5e-04, Method: Compositional matrix adjust.
Identities = 35/121 (28%), Positives = 55/121 (45%)
Frame = -3
Query: 291 YAVVTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHR 350
YA T E + I + M G L L + G+ T ++ AA++ G+ + R ++R
Sbjct: 353 YAFQTPEKLCFILDLMNGGDLHYHL-SQHGV-FTEKEVRFYAAEVMLGLEHMHSRFVVYR 180
Query: 351 DLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDV 410
DL+ ANIL+ + +I+D GLA + A G + APE + G S
Sbjct: 179 DLKPANILLDENGHVRISDLGLACDFSKKKPHASVGTH---GYMAPEVLMKGQAYDSSAD 9
Query: 411 W 411
W
Sbjct: 8 W 6
>11185
Length = 473
Score = 42.0 bits (97), Expect = 5e-04, Method: Compositional matrix adjust.
Identities = 31/133 (23%), Positives = 56/133 (42%), Gaps = 21/133 (15%)
Frame = +1
Query: 330 DMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNE-----YTAR 384
D + G+ +I + DLR + +L+ + K ADFGL+++ +N A
Sbjct: 13 DFGIHLVTGLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAE 192
Query: 385 EGAKFPIK----------------WTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPY 428
G ++ I+ + APE +I SD+W+ G + E+ + R+
Sbjct: 193 AGDQWNIQSAEEMMKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSGSRL-- 366
Query: 429 PGMTNPEVIQNLE 441
+PE + LE
Sbjct: 367 SAKPSPEFLNLLE 405
>21433
Length = 590
Score = 42.0 bits (97), Expect = 6e-04, Method: Compositional matrix adjust.
Identities = 25/89 (28%), Positives = 41/89 (46%)
Frame = +2
Query: 334 QIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKW 393
Q++ + + R IHRD++ N+L+ KIADFG + + T G + +
Sbjct: 191 QLSSALEYCHYRKVIHRDIKPENLLLGLKGDLKIADFGWSVHAPSSRRTTMCGT---LDY 361
Query: 394 TAPEAINYGTFTIKSDVWSFGILLTEIVT 422
PE + T D+WS G+L E +
Sbjct: 362 LPPEMVEGKTHDENVDLWSLGVLCYEFLV 448
>12786
Length = 460
Score = 40.4 bits (93), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 30/108 (27%), Positives = 52/108 (48%), Gaps = 22/108 (20%)
Frame = -3
Query: 348 IHRDLRAAN-ILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPI-KWTAPEAINYGT-- 403
IH DL+ AN +LV+ L K+ DFG+A ++ ++ + + ++ + +PEAI
Sbjct: 344 IHSDLKPANFMLVAGNL--KLIDFGIANTLQQDKTSVLKDSRVGTPSYMSPEAIMAACDD 171
Query: 404 ------------------FTIKSDVWSFGILLTEIVTHGRIPYPGMTN 433
++SDVWS G +L +V +GR P+ + N
Sbjct: 170 SADDSMEEDGHRTKPKYKVGVRSDVWSLGCILYNMV-YGRTPFQHIKN 30
>18481
Length = 437
Score = 40.0 bits (92), Expect = 0.002, Method: Composition-based stats.
Identities = 20/64 (31%), Positives = 36/64 (56%), Gaps = 3/64 (4%)
Frame = -1
Query: 322 KLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCK---IADFGLARLIED 378
+ T+ +L ++ Q+ + FI ++ +IHRDL+ N L+ C I DFGL++ +D
Sbjct: 209 RFTLKTILMVSDQLLSRLEFIHQKCFIHRDLKPDNFLMGLGRHCHRLYIIDFGLSKRYKD 30
Query: 379 NEYT 382
+ T
Sbjct: 29 TQGT 18
>28638
Length = 1458
Score = 40.0 bits (92), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 31/111 (27%), Positives = 55/111 (49%), Gaps = 4/111 (3%)
Frame = -1
Query: 316 KTPSGIKLTINKLLDMAAQIAEGMAFIE--ERNYIHRDLRAANILVSD--TLSCKIADFG 371
+T G+ L + + A Q+ + F+ E N IH DL+ NIL+ + + KI DFG
Sbjct: 861 QTLEGVSLNLTR--KFAQQLCTALLFLATPEMNIIHCDLKPENILLCNPKRSAIKIVDFG 688
Query: 372 LARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVT 422
+ + Y + ++F + +PE + + + D+WS G +L E+ T
Sbjct: 687 SSCQLGQRIYQYIQ-SRF---YRSPEVLLGVPYDLAIDMWSLGCILVEMHT 547
>17286
Length = 489
Score = 39.7 bits (91), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 18/60 (30%), Positives = 35/60 (58%)
Frame = +3
Query: 44 PASPLQDNLVIALHSYEPSHDGDLGFEKGEQLRILEQSGEWWKAQSLTTGQEGFIPFNFV 103
P + ++ A++ + P DG+LGF++G+ + ++ Q E W S+ G+ G+ P N+V
Sbjct: 3 PTAGVKQPCARAIYDFLPESDGELGFQEGDMITLISQVDENWFEGSV-HGKVGYFPINYV 179
>29243
Length = 1147
Score = 39.7 bits (91), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 29/100 (29%), Positives = 47/100 (47%), Gaps = 2/100 (2%)
Frame = +2
Query: 101 NFVAKANSLEPEPWFFKNLSRKDAERQLLAPGNTHGSFLIRESES--TAGSFSLSVRDFD 158
++V + SLE W+ + R A++ L + G+FLIR + + G SLS++
Sbjct: 269 DYVNEPCSLESYNWYVGIMERPVAQKXLDTCPD--GTFLIRVTNNPLRRGELSLSIK--- 433
Query: 159 QNQGEVVKHYKIRNLDNGGFYISPRITFPGLHELVRHYTN 198
V+H K+ G FY++ F + LV HY N
Sbjct: 434 --YANAVRHIKVNRNPQGRFYLADGRYFDNIQSLVDHYEN 547
>32264
Length = 287
Score = 39.3 bits (90), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 18/45 (40%), Positives = 27/45 (60%)
Frame = +1
Query: 440 LERGYRMVRPDNCPEELYQLMRLCWKERPEDRPTFDYLRSVLEDF 484
+E GYR+ + P+ +Y+LM CW+ PE RP F L + L+D
Sbjct: 1 IEDGYRLQQNPQTPDSVYKLMLRCWEYVPEKRPHFKELYTSLKDI 135
>27287
Length = 514
Score = 37.0 bits (84), Expect = 0.017, Method: Compositional matrix adjust.
Identities = 15/43 (34%), Positives = 24/43 (55%)
Frame = -2
Query: 446 MVRPDNCPEELYQLMRLCWKERPEDRPTFDYLRSVLEDFFTAT 488
M +P E++ +M CW+E P DRP+F L L+ T++
Sbjct: 513 MKKPPYASSEMFGIMHSCWQEDPNDRPSFSRLVQELDKMLTSS 385
>36481
Length = 806
Score = 36.6 bits (83), Expect = 0.021, Method: Compositional matrix adjust.
Identities = 39/154 (25%), Positives = 66/154 (42%), Gaps = 13/154 (8%)
Frame = +2
Query: 222 EDEWEVPRET-----LKLVERLGAGQFGEV--WMGYYNGHTKVAVKSLKQGSMSPDAFLA 274
+D W R T +KL G G FG+V G +A+K +K +A
Sbjct: 323 KDIWCTMRGTSSTNDMKLCPHWGEGTFGKVVQCKDLLKG-DDIALKIIKNVDKYREAAKL 499
Query: 275 EANLMKQLQHQ------RLVRLYAVVTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKL 328
E N++++L+ + V++ I+ +M S+ DFLK S I ++
Sbjct: 500 EINVLEKLREKDPHAKHMCVQMLDWFDYHGHVCISFHMLGLSVFDFLKDNSYGAYPIEQV 679
Query: 329 LDMAAQIAEGMAFIEERNYIHRDLRAANILVSDT 362
++ Q+ + F+ E H DL+ NIL D+
Sbjct: 680 RHISYQLCYAVNFLHENQLTHTDLKPENILFVDS 781
>21210
Length = 518
Score = 36.6 bits (83), Expect = 0.021, Method: Compositional matrix adjust.
Identities = 25/85 (29%), Positives = 42/85 (49%), Gaps = 3/85 (3%)
Frame = +3
Query: 396 PEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNP-EVIQNLERGYRMVRPDN--C 452
P A ++G + ++SDVWS GI L E+ T GR PY + + +Q + RG P +
Sbjct: 42 PRASSHG-YDVRSDVWSLGITLMELAT-GRFPYRKWVSIFDQLQQVVRGVAPCLPHDGAF 215
Query: 453 PEELYQLMRLCWKERPEDRPTFDYL 477
+ + C + + RP ++ L
Sbjct: 216 SHDFVNFVNKCLTKDEKQRPKYNKL 290
>32000
Length = 644
Score = 36.2 bits (82), Expect = 0.030, Method: Compositional matrix adjust.
Identities = 30/97 (30%), Positives = 48/97 (49%), Gaps = 3/97 (3%)
Frame = -1
Query: 362 TLSCKIADFGLARL--IEDNEYTAREGAKFPIKWTAPEAINYGTF-TIKSDVWSFGILLT 418
T KIADFGLAR+ + YT + + APE + F ++ D+WS G +
Sbjct: 581 TAKMKIADFGLARVFGLPVRTYTHEV---ITLWYRAPEILLGCRFYSVPVDIWSLGCIFV 411
Query: 419 EIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDNCPEE 455
E++T R +PG + +++ YR+ R P+E
Sbjct: 410 EMMTR-RALFPGDS------EIDQLYRIFRTLGTPDE 321
>07933
Length = 728
Score = 35.8 bits (81), Expect = 0.046, Method: Compositional matrix adjust.
Identities = 14/29 (48%), Positives = 16/29 (55%)
Frame = +3
Query: 449 PDNCPEELYQLMRLCWKERPEDRPTFDYL 477
P+ CP LY +M CW P RPTF L
Sbjct: 3 PNYCPNLLYNIMMQCWSAEPSARPTFHKL 89
>38046
Length = 446
Score = 34.3 bits (77), Expect = 0.11, Method: Composition-based stats.
Identities = 14/25 (56%), Positives = 20/25 (80%)
Frame = -1
Query: 335 IAEGMAFIEERNYIHRDLRAANILV 359
IA+ MA++E+ N+IHR+L NILV
Sbjct: 98 IADAMAYMEKENFIHRNLGDRNILV 24
>20559
Length = 430
Score = 34.3 bits (77), Expect = 0.12, Method: Composition-based stats.
Identities = 21/67 (31%), Positives = 37/67 (55%), Gaps = 4/67 (5%)
Frame = -2
Query: 235 VERLGAGQFGEVWMGY-YNGHTKVAVKSLK---QGSMSPDAFLAEANLMKQLQHQRLVRL 290
+E++G G +G V+ H VA+K ++ P + L E L+K+L+H+ +VRL
Sbjct: 360 LEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHRNIVRL 181
Query: 291 YAVVTQE 297
+ V+ E
Sbjct: 180 HDVLHSE 160
>29590
Length = 320
Score = 33.9 bits (76), Expect = 0.15, Method: Composition-based stats.
Identities = 14/41 (34%), Positives = 27/41 (65%)
Frame = +3
Query: 393 WTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTN 433
+ APE ++Y +I++D+WS G+L ++T P+ G+T+
Sbjct: 72 YVAPEVLDYEPLSIQTDMWSLGVLSYVMLTACS-PFVGITS 191
>11228
Length = 2155
Score = 33.1 bits (74), Expect = 0.27, Method: Compositional matrix adjust.
Identities = 20/40 (50%), Positives = 25/40 (62%)
Frame = -1
Query: 114 WFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLS 153
W+ L R AE +LL + GS+L+RESES GSF LS
Sbjct: 1972 WYHGRLGRAGAE-ELLRDQDA-GSYLVRESESKLGSFVLS 1859
>37260
Length = 401
Score = 32.7 bits (73), Expect = 0.33, Method: Composition-based stats.
Identities = 19/69 (27%), Positives = 35/69 (50%)
Frame = -1
Query: 101 NFVAKANSLEPEPWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLSVRDFDQN 160
+F+ L+ W++ LS ++AE +L+ GSFL+R+S + SLS +
Sbjct: 221 DFLESMKQLKDCGWYWGPLSYEEAESKLM--DKRDGSFLVRDSSNENYILSLSFKSMGHV 48
Query: 161 QGEVVKHYK 169
++H+K
Sbjct: 47 HHTRIEHHK 21
>15741
Length = 402
Score = 32.3 bits (72), Expect = 0.51, Method: Composition-based stats.
Identities = 14/42 (33%), Positives = 20/42 (47%)
Frame = -3
Query: 317 TPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANIL 358
T + LT A +A GMA + +HRD+ A N+L
Sbjct: 127 TSTANDLTARDFFSFALHVARGMAHVANNKIVHRDVAARNVL 2
>06462
Length = 1511
Score = 30.8 bits (68), Expect = 1.1, Method: Compositional matrix adjust.
Identities = 30/116 (25%), Positives = 48/116 (41%), Gaps = 6/116 (5%)
Frame = +1
Query: 112 EPWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLSVRDFDQNQGEVVKHYKIR 171
E W+ +SR++AE+ L G FL+RES F LS ++ G+ + +
Sbjct: 1090 ELWYHGKMSRREAEKLL----GKDGDFLVRESGHNXSQFVLS----GKHHGQFI---HLL 1236
Query: 172 NLDNGGFYISPRITFPGLHELVRHYTN-----ASDGLCTRLSRPCQTQKPQ-KPWW 221
+D G + F + LV ++ + S G L RP P +P W
Sbjct: 1237 LVDPDGIVRTKDYIFDNISHLVSYHCHHGMPIVSHGSQLTLLRPINVSVPAYRP*W 1404
>20131
Length = 574
Score = 30.8 bits (68), Expect = 1.3, Method: Compositional matrix adjust.
Identities = 15/53 (28%), Positives = 28/53 (52%), Gaps = 1/53 (1%)
Frame = -2
Query: 54 IALHSYEPSHDGDLGFEKGEQLRILEQSGEWWKAQSLTTGQE-GFIPFNFVAK 105
+A++SY DL F +G+ + + ++ +WW T G++ G P +V K
Sbjct: 471 VAMYSYVSGETADLTFNEGDMILVTKKDEDWWTG---TLGEKTGMFPSTYVKK 322
>32357
Length = 625
Score = 30.8 bits (68), Expect = 1.4, Method: Compositional matrix adjust.
Identities = 17/52 (32%), Positives = 33/52 (63%), Gaps = 1/52 (1%)
Frame = -2
Query: 233 KLVERLGAGQFGEVWMGYYN-GHTKVAVKSLKQGSMSPDAFLAEANLMKQLQ 283
+L++++G+G FGE+++G +N +VAVK + + P + E+ L + LQ
Sbjct: 429 RLMKKIGSGSFGEIYLGVHNTSGEEVAVKLELKNAKHPQLYY-ESKLYRVLQ 277
>13664
Length = 507
Score = 30.0 bits (66), Expect = 2.1, Method: Compositional matrix adjust.
Identities = 16/56 (28%), Positives = 27/56 (48%)
Frame = +2
Query: 42 NPPASPLQDNLVIALHSYEPSHDGDLGFEKGEQLRILEQSGEWWKAQSLTTGQEGF 97
+P S + V+AL+ Y+ +L G+ + +L + E W L GQ+GF
Sbjct: 338 SPLGSTRKPKKVVALYDYKAQRSDELTILSGDVIMLLHKDSESWWMGELLDGQQGF 505
>25100
Length = 699
Score = 28.9 bits (63), Expect = 5.5, Method: Compositional matrix adjust.
Identities = 11/38 (28%), Positives = 19/38 (50%)
Frame = +3
Query: 184 ITFPGLHELVRHYTNASDGLCTRLSRPCQTQKPQKPWW 221
+T+ + L+ +T+ L + SR C+ K K WW
Sbjct: 150 LTYCSSYILIHMHTDTHKDLFLKFSRKCRENKADKIWW 263
>17516
Length = 453
Score = 28.5 bits (62), Expect = 6.0, Method: Composition-based stats.
Identities = 27/104 (25%), Positives = 50/104 (48%), Gaps = 7/104 (6%)
Frame = -3
Query: 393 WTAPEAI-NYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRM-VRPD 450
+ APE + G + +K+DV+S I+L E+ +G+ +++ + LE + +RP
Sbjct: 421 YMAPEVLLQKGQYDMKADVYSLAIILWEL-WYGQDAADHISS-HLFGRLEDAVQAGLRPS 248
Query: 451 ---NC--PEELYQLMRLCWKERPEDRPTFDYLRSVLEDFFTATE 489
C P++ +L++ W+ RPT EDF T+
Sbjct: 247 VTMTCKPPDDWLKLLQSGWEFHASKRPTSRDAAEFFEDFLERTK 116
>18050
Length = 448
Score = 28.5 bits (62), Expect = 6.2, Method: Compositional matrix adjust.
Identities = 16/57 (28%), Positives = 29/57 (50%), Gaps = 1/57 (1%)
Frame = +3
Query: 53 VIALHSYEPSHDGDLGFEKGEQLRILEQSGE-WWKAQSLTTGQEGFIPFNFVAKANS 108
VIA HSYE L E G+ + + + + W++ + + G G+ P ++ + NS
Sbjct: 24 VIAKHSYESDEPDVLQLELGDVVNVSRKLPDGWYQGERIRDGAVGWFPGSYTEELNS 194
>30665
Length = 530
Score = 28.5 bits (62), Expect = 7.1, Method: Compositional matrix adjust.
Identities = 10/19 (52%), Positives = 17/19 (89%)
Frame = +3
Query: 299 IYIITEYMENGSLVDFLKT 317
++++TE+ ENGSL D+LK+
Sbjct: 441 LWLLTEFHENGSLSDYLKS 497
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000362658 | hsapiens_gene_ensembl | Proto-oncogene
tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK) (Lymphocyte
cell-specific protein-tyrosine kinase) (LSK) (T cell- specific
protein-tyrosine kinase). [Source:Uniprot/SWISSPROT;Acc:P06239]
(496 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
06405 298 3e-81
21808 284 3e-77
11780 206 4e-73
04852 162 4e-40
09007 158 4e-39
07291 139 3e-33
17300 123 2e-31
20640 124 7e-29
14116 121 6e-28
07940 110 1e-24
18996 107 7e-24
17637 105 4e-23
22005 84 6e-23
08294 104 9e-23
14477 94 1e-19
01718 91 9e-19
19301 86 3e-17
13305 84 1e-16
13592 78 9e-15
18921 77 1e-14
12721 77 1e-14
07833 77 1e-14
01060 76 3e-14
29581 75 4e-14
17253 73 3e-13
14126 73 3e-13
01707 72 5e-13
01756 69 6e-12
00300 68 6e-12
00715 67 1e-11
01966 65 6e-11
14420 65 7e-11
27546 64 1e-10
18484 64 2e-10
12672 63 2e-10
04591 61 1e-09
25550 60 1e-09
07836 59 3e-09
31885 57 2e-08
17975 57 3e-08
13066 56 3e-08
19094 55 5e-08
09606 55 7e-08
03240 54 1e-07
30755 51 1e-06
21079 51 1e-06
15910 50 3e-06
04138 49 3e-06
13212 49 3e-06
26711 47 1e-05
35671 47 3e-05
01392 45 5e-05
19761 45 7e-05
16708 45 8e-05
37602 45 8e-05
26560 44 1e-04
27405 42 5e-04
11185 42 5e-04
21433 42 6e-04
12786 40 0.001
18481 40 0.002
28638 40 0.002
17286 40 0.003
29243 40 0.003
32264 39 0.003
27287 37 0.017
36481 37 0.021
21210 37 0.021
32000 36 0.030
07933 36 0.046
38046 34 0.11
20559 34 0.12
29590 34 0.15
11228 33 0.27
37260 33 0.33
15741 32 0.51
06462 31 1.1
20131 31 1.3
32357 31 1.4
13664 30 2.1
25100 29 5.5
17516 28 6.0
18050 28 6.2
30665 28 7.1
>06405
Length = 1965
Score = 298 bits (764), Expect = 3e-81, Method: Compositional matrix adjust.
Identities = 161/352 (45%), Positives = 229/352 (65%), Gaps = 8/352 (2%)
Frame = +1
Query: 142 ESESTAGSFSLSVRDFDQNQGEVVKHYKIRNLDNGGFYISPRITFPGLHELVRHYTNASD 201
ESES+ G S+SVR F+ V HY+I D+G +++ F L ELV H++ +D
Sbjct: 1 ESESSPGQRSISVR-FEGR----VYHYRITE-DDGKVFVTQEHRFNTLAELVHHHSIHAD 162
Query: 202 GLCTRLSRPCQTQKPQKPWW------EDEWEVPRETLKLVERLGAGQFGEVWMGYYNGHT 255
GL T L P K QKP D WE+ R + + RLG GQ+G+V+ + +
Sbjct: 163 GLVTTLLYPAP--KRQKPTVFGVSPEPDRWEIERTEIAMKHRLGGGQYGDVYEAMWKRYN 336
Query: 256 K-VAVKSLKQGSMSPDAFLAEANLMKQLQHQRLVRLYAVVTQEP-IYIITEYMENGSLVD 313
K VAVK+LK+ +M+ + FL EA +MK+++H LV+L V T+EP YI+TE+M +G+L+D
Sbjct: 337 KIVAVKTLKEDTMALNDFLEEAAIMKEMKHPNLVQLLGVCTREPPFYIVTEFMPHGNLLD 516
Query: 314 FLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLA 373
+L++ + + L+ MA QIA GMA++E +N+IHRDL A N LV+D+ K+ADFGLA
Sbjct: 517 YLRSSTREENGPTALMYMATQIASGMAYLETKNFIHRDLAARNCLVADSNMVKVADFGLA 696
Query: 374 RLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTN 433
RL++D+ YTA GAKFPIKWTAPE + + F+ +SD+W+FG+LL E+ T+G PYPG+
Sbjct: 697 RLMKDDTYTAHIGAKFPIKWTAPEGLAFNRFSTRSDIWAFGVLLWELATYGMSPYPGVEL 876
Query: 434 PEVIQNLERGYRMVRPDNCPEELYQLMRLCWKERPEDRPTFDYLRSVLEDFF 485
EV LERGYRM RP P ++Y LM CW+ P+DRPTF + +LE+ F
Sbjct: 877 TEVYHLLERGYRMERPPGTPADVYILMLKCWQWDPKDRPTFKEIHFLLENMF 1032
>21808
Length = 1011
Score = 284 bits (726), Expect(2) = 3e-77, Method: Compositional matrix adjust.
Identities = 138/225 (61%), Positives = 175/225 (77%), Gaps = 1/225 (0%)
Frame = +1
Query: 249 GYYNGHTKVAVKSLKQGSMSPDAFLAEANLMKQLQHQRLVRLYAVVTQE-PIYIITEYME 307
G +N T VA+K+LK G+M P FLAEA +MK+L+H +L++LYAV TQ+ PI+IITE M+
Sbjct: 4 GLWNNTTPVAIKTLKSGTMDPKDFLAEAQIMKKLRHPKLIQLYAVCTQDDPIFIITELMK 183
Query: 308 NGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKI 367
NGSL++FL+ G L + L+D+ AQIA GMA++E +NYIHRDL A NILVSD + KI
Sbjct: 184 NGSLLEFLQG-KGRVLKLPALIDIGAQIACGMAYLESQNYIHRDLAARNILVSDNNTVKI 360
Query: 368 ADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIP 427
ADFGLAR+I+++EY AR GA+FPIKWTAPEA NY FTIKSDVWSFGILLTE VT+GR+P
Sbjct: 361 ADFGLARVIKEDEYEARVGARFPIKWTAPEAANYNRFTIKSDVWSFGILLTETVTYGRVP 540
Query: 428 YPGMTNPEVIQNLERGYRMVRPDNCPEELYQLMRLCWKERPEDRP 472
YPGMTN EV+ +E GYRM P CP+ LY +M CW++ +RP
Sbjct: 541 YPGMTNAEVLHQVEHGYRMPCPPGCPKPLYDIMLECWRKEEMERP 675
Score = 23.5 bits (49), Expect(2) = 3e-77, Method: Compositional matrix adjust.
Identities = 10/22 (45%), Positives = 14/22 (63%)
Frame = +2
Query: 472 PTFDYLRSVLEDFFTATEGQYQ 493
PTF+ L+ LE+FFT Y+
Sbjct: 674 PTFETLQWKLEEFFTMDSKDYR 739
>11780
Length = 1713
Score = 206 bits (524), Expect(2) = 4e-73, Method: Compositional matrix adjust.
Identities = 126/341 (36%), Positives = 189/341 (55%), Gaps = 10/341 (2%)
Frame = +3
Query: 69 FEKGEQLRILEQSGE--WWKAQSLTTGQEGFIPFNFVA--KANSLEPEPWFFKNLSRKDA 124
F+KG+ L I + + W+KA + G+EG IP N+V K +L PWF ++R+ A
Sbjct: 111 FQKGDLLVIRRATSDRMWYKACD-SNGREGMIPANYVQPRKVVTLHAMPWFHGKITRQQA 287
Query: 125 ERQLLAPGNTHGSFLIRESESTAGSFSLSVRDFDQNQGEVVKHYKIRNLDNGGFYISPRI 184
E +LL P G FLIRES + G ++L V + V+HY+I +N I
Sbjct: 288 E-ELLKP-REDGLFLIRESSNYPGDYTLCVCHLGK-----VEHYRILYRENQ-LTIDEEG 443
Query: 185 TFPGLHELVRHYTNASDGLCTRLSRPCQTQKPQ------KPWWEDEWEVPRETLKLVERL 238
F L ELV+HY +DGLCT+L+RP Q + + W + + L++ E +
Sbjct: 444 FFRNLDELVKHYLADADGLCTQLTRPVTKQGGNFGTVSLQEFKSGGWVIAXQDLEIGEAI 623
Query: 239 GAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPDAFLAEANLMKQLQHQRLVRLYAVVTQEP 298
G G FG+V+ G Y G VA+K LK +FL EA++M L+H LVRL VV E
Sbjct: 624 GKGDFGDVYKGMYRGQP-VAIKQLKDKDRGEQSFLQEASVMTSLRHDNLVRLIGVVLGET 800
Query: 299 IYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANIL 358
I+++TE+M G+LV++L++ +T ++ A M ++E + +HRDL A N+L
Sbjct: 801 IFLVTEFMGKGNLVEYLRSRGRSVITKKDQINFATDTCAAMEYLESKRLVHRDLAARNVL 980
Query: 359 VSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAI 399
V D K++DFGLA+ + ++ + KFPIKWTAPEA+
Sbjct: 981 VHDDGKAKVSDFGLAKFGDFSQTS----VKFPIKWTAPEAL 1091
Score = 87.0 bits (214), Expect(2) = 4e-73, Method: Compositional matrix adjust.
Identities = 39/80 (48%), Positives = 56/80 (70%)
Frame = +1
Query: 404 FTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDNCPEELYQLMRLC 463
FT KSD+WSFGILL EI + GR+PYP + +V+ ++ERGYRM P+ CP E+Y +M+
Sbjct: 1105 FTSKSDMWSFGILLWEIYSFGRVPYPRIPLTDVVMHVERGYRMEAPEGCPPEIYSIMKQA 1284
Query: 464 WKERPEDRPTFDYLRSVLED 483
W+ P +RPTF + + L +
Sbjct: 1285 WELDPNERPTFKSVLARLNN 1344
>04852
Length = 1462
Score = 162 bits (409), Expect = 4e-40, Method: Compositional matrix adjust.
Identities = 98/254 (38%), Positives = 133/254 (52%), Gaps = 31/254 (12%)
Frame = +1
Query: 255 TKVAVKSLKQ--GSMSPDAFLAEANLMKQLQ----HQRLVRLYAVVTQE-PIYIITEYME 307
+ VAVK L+ ++ F+ E +MK ++ H +V TQ P+++I E+ +
Sbjct: 22 STVAVKMLRDIVTAVEEQDFVQELQVMKAVKKMGSHINIVNFLGCCTQGGPLWVIVEFAK 201
Query: 308 NGSLVDFL-----------------------KTPSGIKLTINKLLDMAAQIAEGMAFIEE 344
NG+L DFL KTP G + LL A QIA GM F+
Sbjct: 202 NGNLRDFLESCRDGINGYGKFVSPQDPGWYTKTPGGHVIRRKNLLSYAFQIARGMEFLAS 381
Query: 345 RNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTF 404
R IHRDL A N+LV++ KIADFGL+R + Y R G + P+KW APEA+ +
Sbjct: 382 RKCIHRDLAARNVLVTEEHVLKIADFGLSR--TGDYYKKRSGGRLPVKWMAPEALFDMRY 555
Query: 405 TIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQN-LERGYRMVRPDNCPEELYQLMRLC 463
T KSDVWSFG++L EI + G +PY + N E+ L+ YRM RP+ LY +M C
Sbjct: 556 TTKSDVWSFGVVLWEIFSLGGMPYASIPNEELYSKLLDDAYRMPRPELASGNLYAIMERC 735
Query: 464 WKERPEDRPTFDYL 477
W RP DRP F L
Sbjct: 736 WLNRPSDRPEFSQL 777
>09007
Length = 1440
Score = 158 bits (400), Expect = 4e-39, Method: Compositional matrix adjust.
Identities = 88/266 (33%), Positives = 145/266 (54%), Gaps = 15/266 (5%)
Frame = -1
Query: 227 VPRETLKLVERLGAGQFGEV----WMGYYNGHTKVAVKSLKQGSMSPDA--FLAEANLMK 280
+ ++ + L + LG G FG V W +VAVK L + + D FL E +M+
Sbjct: 888 ISKDCVALSKSLGQGHFGTVRQAIWTAESGEKVQVAVKCLSKDKIHKDGQEFLKETAIMQ 709
Query: 281 QLQHQRLVRLYAVVTQE--PIYIITEYMENGSLVDFLKTPSG-IKLTINKLLDMAAQIAE 337
L H+ +VR+Y VV I ++TE SL++ +K S + ++ +L D + Q+ +
Sbjct: 708 MLDHENIVRVYGVVMDNGADIMLVTELAPMRSLLECVKEVSARVDFSVPRLCDFSQQVCD 529
Query: 338 GMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLA-RLIEDNEYTAREGA---KFPIKW 393
GM+++E + +HRDL A NIL+ KI+D G++ L EY + + + W
Sbjct: 528 GMSYLESKRLVHRDLAARNILLFSKSKVKISDVGVSGALGAGKEYYQSQQTIHLQNAVAW 349
Query: 394 TAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLE--RGYRMVRPDN 451
APE+ F+ SDVW+FG+LL E THG P+ G+ ++++ ++ + R+ +PD
Sbjct: 348 CAPESFRNLCFSSASDVWAFGVLLWEFFTHGFQPWAGLNGQQIMEAVDAPQSQRLEQPDL 169
Query: 452 CPEELYQLMRLCWKERPEDRPTFDYL 477
CP+E Y +M CW++ P+ RPTF L
Sbjct: 168 CPKEYYAVMLKCWEQEPQRRPTFSQL 91
>07291
Length = 833
Score = 139 bits (349), Expect = 3e-33, Method: Compositional matrix adjust.
Identities = 67/164 (40%), Positives = 104/164 (63%), Gaps = 2/164 (1%)
Frame = +1
Query: 323 LTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGL-ARLIEDNEY 381
LT+ +LLD QIA+GMA+++E +HR+L A N +V++ +++D+G+ L + Y
Sbjct: 40 LTVVQLLDFGRQIADGMAYLQEVKVVHRNLAARNCIVTEDGRLQLSDYGVTGSLFPQSYY 219
Query: 382 TAREG-AKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNL 440
TA + A+ +KW APE I+ F+ KSDVW+FG++L E++T G PYP + N ++ L
Sbjct: 220 TADDSPARDLVKWMAPETIDNFHFSSKSDVWAFGVVLWELLTRGITPYPDVENSSLLPYL 399
Query: 441 ERGYRMVRPDNCPEELYQLMRLCWKERPEDRPTFDYLRSVLEDF 484
+ G+RM +P PE +Y++M CW E PE RP F L L+ F
Sbjct: 400 KEGHRMKKPKQSPEPVYEMMTACWNESPEQRPDFAELNDQLKTF 531
>17300
Length = 480
Score = 123 bits (308), Expect(2) = 2e-31, Method: Compositional matrix adjust.
Identities = 57/116 (49%), Positives = 82/116 (70%), Gaps = 4/116 (3%)
Frame = +1
Query: 335 IAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDN----EYTAREGAKFP 390
I+ GM + + Y+HRDL A NILV++ L CK+ADFGL+R IE + YT + G K P
Sbjct: 1 ISSGMGXLADMGYVHRDLAARNILVNEILVCKVADFGLSREIESDTTEGAYTTK-GGKIP 177
Query: 391 IKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRM 446
++WTAPEAI Y FT SDVWSFG+++ E++++G PY +N +VI+ +E+GYR+
Sbjct: 178 VRWTAPEAIAYRKFTSASDVWSFGVVMWEVMSYGERPYWNWSNQDVIKAVEKGYRL 345
Score = 30.8 bits (68), Expect(2) = 2e-31, Method: Composition-based stats.
Identities = 13/39 (33%), Positives = 19/39 (48%)
Frame = +2
Query: 451 NCPEELYQLMRLCWKERPEDRPTFDYLRSVLEDFFTATE 489
+CPE L+QLM W++ RP + L+ A E
Sbjct: 356 DCPEALHQLMLDAWQKERSHRPKMSMVVKTLDKLIRAPE 472
>20640
Length = 1492
Score = 124 bits (312), Expect = 7e-29, Method: Compositional matrix adjust.
Identities = 61/146 (41%), Positives = 84/146 (57%), Gaps = 1/146 (0%)
Frame = +1
Query: 345 RNYIHRDLRAANILVSDTLSCKIADFGLARLIED-NEYTAREGAKFPIKWTAPEAINYGT 403
R Y+HRDL N LV L KI+DFGLAR + + Y E PI+W EAI Y
Sbjct: 1 RGYVHRDLATRNCLVGHDLVVKISDFGLARSVHSVDYYRGSEHDAIPIRWMPLEAILYNK 180
Query: 404 FTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDNCPEELYQLMRLC 463
F+ +SDVWSFG++L EI PY G+T+ EV++ ++ G + P+ P +Y+LM+ C
Sbjct: 181 FSTQSDVWSFGVVLWEIFAFALQPYYGLTHEEVVRFVKEGKVLACPERTPPPMYELMKQC 360
Query: 464 WKERPEDRPTFDYLRSVLEDFFTATE 489
W RP RP+F L LE+ + E
Sbjct: 361 WHRRPATRPSFHTLHKTLENMHSKYE 438
>14116
Length = 1017
Score = 121 bits (304), Expect = 6e-28, Method: Compositional matrix adjust.
Identities = 72/216 (33%), Positives = 117/216 (54%), Gaps = 13/216 (6%)
Frame = -1
Query: 227 VPRETLKLVERLGAGQFGEVWMGYYN-----GHTKVAVKSLKQGS---MSPDAFLAEANL 278
+ RE L + E +G G FG V G+ G VAVK+L + + +FL EA +
Sbjct: 645 IDREFLTMGEEIGKGNFGCVKRGFLTLPEQKGDILVAVKTLHNNNPREIELQSFLQEALI 466
Query: 279 MKQLQHQRLVRLYAV---VTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQI 335
MK H ++ L + + P+ ++ +M++G L+ +++ + TI L+ I
Sbjct: 465 MKDFHHSNVLTLIGICLNLDDMPL-VVLPFMKHGDLLTYIRDDQH-QPTIKDLIMYGVDI 292
Query: 336 AEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREG--AKFPIKW 393
A GM ++ ++HRDL A N ++ + K+ADFGLAR I + EY + E AK P+KW
Sbjct: 291 ARGMDYLAGLKFVHRDLAARNCMLDEDFHVKVADFGLARDIYEKEYYSSENKKAKLPVKW 112
Query: 394 TAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYP 429
A E++ G + K+DVWS+G++L E++T G P
Sbjct: 111 MALESLEKGNYDSKTDVWSYGVVLWELLTRGSDALP 4
>07940
Length = 1336
Score = 110 bits (276), Expect = 1e-24, Method: Compositional matrix adjust.
Identities = 84/280 (30%), Positives = 128/280 (45%), Gaps = 70/280 (25%)
Frame = -3
Query: 222 EDEWEVPRETLKLVERLGAGQFGEVW----MGYY--NGHTKVAVKSLKQGSMSPDA--FL 273
+ +WE PRE L L +RLG G FG V MG + N VAVK LK+ + + +
Sbjct: 866 DAKWEFPRERLVLGDRLGEGAFGLVMKGEAMGIFKDNNSVTVAVKMLKEDATDREMMDLI 687
Query: 274 AEANLMKQL-QHQRLVRL----------YAVVTQEPIYIITEYMEN-------------- 308
E +MK + +H+ ++ L Y +V P + +++++
Sbjct: 686 REMEMMKVIGKHKNIINLLGCCTQRGALYVIVEFAPHGNLRDFLKSHRPHGTSYSCIADY 507
Query: 309 -----------------------GSLVDFLKTPSGIK-------------LTINKLLDMA 332
G+ + F+ S + LT L+ A
Sbjct: 506 EQPVITSSSSSFSHPNSASSSAQGTSLGFIPGTSTVSFSTGSHRQDMLKMLTPKDLISYA 327
Query: 333 AQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTARE-GAKFPI 391
Q+A GM ++ + IHRDL A N+LV++ KIADFGL R ++ +Y + + P+
Sbjct: 326 YQVARGMEYLASKQCIHRDLAARNVLVAEEYVLKIADFGLTRNLQQFDYYRKTTDGRLPV 147
Query: 392 KWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGM 431
KW APEA+ +T KSDVWS+G+LL EI T G PYP +
Sbjct: 146 KWMAPEALFDRKYTSKSDVWSYGVLLWEIFTLGGNPYPSV 27
>18996
Length = 491
Score = 107 bits (268), Expect = 7e-24, Method: Compositional matrix adjust.
Identities = 65/158 (41%), Positives = 87/158 (55%), Gaps = 10/158 (6%)
Frame = +2
Query: 348 IHRDLRAANILVSDTLSCKIADFGLARLIE-DNEYTAREGAKFPIKWTAPEAINYGTFTI 406
IHRDL A NILV D KI+DFGLA+ D Y PIKW +PEAI F+
Sbjct: 2 IHRDLAARNILV-DRSCVKISDFGLAQFANADGYYYGISQRDIPIKWYSPEAIETCKFSS 178
Query: 407 KSDVWSFGILLTEIVTHGRIP--YPG--MTNPEVIQNLERGYRMVRPDNCPEELY-QLMR 461
SDVWS+G+ L E+ + G IP PG +T E + L +G R+ +P+ C + +Y +LMR
Sbjct: 179 YSDVWSYGVTLFEMFSRGEIPNLLPGHDLTQEEFLNRLRKGERLPKPELCSDFVYSELMR 358
Query: 462 LCWKERPEDRPTFDYLRSVLE----DFFTATEGQYQPQ 495
CW E P+ RPTF + ++ D + G Q Q
Sbjct: 359 PCWHEMPKSRPTFHQIIQIIAREMGDNISGXAGSTQQQ 472
>17637
Length = 447
Score = 105 bits (262), Expect = 4e-23, Method: Compositional matrix adjust.
Identities = 50/132 (37%), Positives = 77/132 (58%), Gaps = 1/132 (0%)
Frame = +1
Query: 356 NILVSDTLSCKIADFGLARLIEDNEYTAR-EGAKFPIKWTAPEAINYGTFTIKSDVWSFG 414
N ++ D L K+ D L+R + +Y +G PIKW + EA+ + SDVWSFG
Sbjct: 1 NCVIDDQLRVKLTDSALSRDLFSGDYNCLGDGEYRPIKWLSLEALQKSHYNEGSDVWSFG 180
Query: 415 ILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDNCPEELYQLMRLCWKERPEDRPTF 474
+L+ E+ T G++PY + E+ L+ GYR+ +P NCP+EL+ +M CW P +RP+F
Sbjct: 181 VLMWEMCTLGKLPYAEIDPYEMEHYLKDGYRLAQPFNCPDELFTIMAYCWASMPAERPSF 360
Query: 475 DYLRSVLEDFFT 486
L+ L +F T
Sbjct: 361 SQLQICLSEFHT 396
>22005
Length = 873
Score = 84.0 bits (206), Expect(2) = 6e-23, Method: Compositional matrix adjust.
Identities = 61/194 (31%), Positives = 93/194 (47%), Gaps = 44/194 (22%)
Frame = +1
Query: 272 FLAEANLMKQLQHQRLVRLYAVVT-QEPIYIITEYMENGSLVDFLK--TPSGIKLTI--- 325
F EA+LM H +V+L V +P+ ++ E+M G L DFL+ +P L +
Sbjct: 151 FEREASLMADFDHPNIVKLLGVCAIGKPMCLLFEFMSKGDLNDFLRLCSPENYNLPVSRS 330
Query: 326 -NKLLDM------------------------------------AAQIAEGMAFIEERNYI 348
N ++D+ + QI+ GMA++ +++Y+
Sbjct: 331 QNLVVDLEDGLRVEVEAEECEKDTQSEDRDCSGMLXTKDQLYISQQISAGMAYLAQKDYV 510
Query: 349 HRDLRAANILVSDTLSCKIADFGLARLIED-NEYTAREGAKFPIKWTAPEAINYGTFTIK 407
HRDL A + S T I+DFGLAR + + Y E PI+W EAI Y F+ +
Sbjct: 511 HRDL-ATRTVXSRTT*S*ISDFGLARSVHSVDYYRGSEQDAIPIRWMPLEAILYSKFSTQ 687
Query: 408 SDVWSFGILLTEIV 421
SDVWSFG++L EI+
Sbjct: 688 SDVWSFGVVLWEIL 729
Score = 42.0 bits (97), Expect(2) = 6e-23, Method: Compositional matrix adjust.
Identities = 16/42 (38%), Positives = 28/42 (66%)
Frame = +3
Query: 427 PYPGMTNPEVIQNLERGYRMVRPDNCPEELYQLMRLCWKERP 468
PY G+T+ EV+ ++ G + +P P ++Y+LM+ CW+ RP
Sbjct: 744 PYYGLTHEEVVNYVKAGKILEQPTKTPHQVYELMKQCWQRRP 869
>08294
Length = 1849
Score = 104 bits (259), Expect = 9e-23, Method: Compositional matrix adjust.
Identities = 58/198 (29%), Positives = 100/198 (50%), Gaps = 13/198 (6%)
Frame = +2
Query: 297 EPIYIITEYMENGSLVDFL-------------KTPSGIKLTINKLLDMAAQIAEGMAFIE 343
EP ++ITEY + G L FL + P+ L +++ L M Q+A GM +
Sbjct: 926 EPHFLITEYCDWGDLKQFLLATRNDNGRGRGTRVPA---LALSQKLGMGQQVAAGMEALS 1096
Query: 344 ERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGT 403
+ +H DL A N+L++ + K+A L+ + +EY P++W PE + +
Sbjct: 1097 NQGLVHGDLAARNVLLTSRMQLKVARPALSGDVYASEYYPLHQRLVPLRWLPPEGVLEDS 1276
Query: 404 FTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDNCPEELYQLMRLC 463
T DVW+FG+ L E++ +PY M++ EV+++L+ + + P L L++ C
Sbjct: 1277 ATTCGDVWAFGVFLWEVLQLADLPYRLMSDEEVLRSLQHSQAALDSPDAPPALLSLLQRC 1456
Query: 464 WKERPEDRPTFDYLRSVL 481
++P RP F + SVL
Sbjct: 1457 TAQQPSQRPPFSEICSVL 1510
>14477
Length = 493
Score = 94.0 bits (232), Expect = 1e-19, Method: Composition-based stats.
Identities = 54/158 (34%), Positives = 87/158 (55%), Gaps = 8/158 (5%)
Frame = -1
Query: 237 RLGAGQFGEVWMGYY---NGHTKVAVKSLKQGSMSPDA---FLAEANLMKQLQHQRLVRL 290
+LGAG FG V G + VA+K LK + P + EA +MK++ H +VRL
Sbjct: 469 KLGAGNFGSVMKGVCRLDDREIPVAIKVLKNADLDPSVQSELIKEAEVMKKMDHMHIVRL 290
Query: 291 YAVVTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHR 350
+ E + ++ E + G L FL P L + +L++ Q+++GM ++E ++HR
Sbjct: 289 IGLCEGETMMLVLELAKLGPLNKFL--PKNKHLPLWNILELMWQVSQGMEYLEANKFVHR 116
Query: 351 DLRAANILVSDTLSCKIADFGLARLI--EDNEYTAREG 386
DL A NIL+ D KI+DFG+++ + E+N Y A+E
Sbjct: 115 DLAARNILLCDEHFAKISDFGMSKTLSRENNYYMAQEA 2
>01718
Length = 959
Score = 91.3 bits (225), Expect = 9e-19, Method: Compositional matrix adjust.
Identities = 70/252 (27%), Positives = 120/252 (47%), Gaps = 13/252 (5%)
Frame = +3
Query: 234 LVERLGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPDAFLAEANLMKQLQHQRLVRLYAV 293
+ E++GAG F EV+ + +V + + + L E L+ +LQH ++R V
Sbjct: 159 ICEKIGAGFFSEVFKVTHRITGQVMALKMNTMTSNRHNMLREVQLLNRLQHANILRFMGV 338
Query: 294 VTQE-PIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDL 352
E ++ +TEY+ +G+L L+ +L + + + +A G+ ++ +IHRDL
Sbjct: 339 CVHEGQLHALTEYIPSGNLEQLLEKKDE-ELPWTQRIQLTLGLARGLDYLHSTRFIHRDL 515
Query: 353 RAANILV----SDTLSCKIADFGLARLIE---DNEYTAREGAKFPIKWTAPEAINYGTFT 405
+ NIL+ + IADFGLA I D E G+ + W APE +N +
Sbjct: 516 TSKNILIRREDNHGYHAVIADFGLATKIPDPLDKEKLPTVGSPY---WMAPEVLNGHFYN 686
Query: 406 IKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLER-GYRMVRPDN----CPEELYQLM 460
++D++S GI++ EI RIP +P+++ + G V CP + QL
Sbjct: 687 ERADLFSVGIIMCEIT--ARIP----ADPDIMPRMNNFGVDYVALSEMISYCPLDYLQLA 848
Query: 461 RLCWKERPEDRP 472
C + P+ RP
Sbjct: 849 FKCCQVDPQKRP 884
>19301
Length = 712
Score = 86.3 bits (212), Expect = 3e-17, Method: Compositional matrix adjust.
Identities = 52/153 (33%), Positives = 84/153 (54%), Gaps = 1/153 (0%)
Frame = +2
Query: 222 EDEWEVPRETLKLVERLGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPDAFLAEANLMKQ 281
+D+WE+P E++ +E LG+G G V++G +VAVK ++ D + +++
Sbjct: 281 QDDWEIPFESITDLEWLGSGAQGAVFLGKLCAE-EVAVKKVR------DIKETDIRNLRK 439
Query: 282 LQHQRLVRLYAVVTQEPIY-IITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMA 340
L H ++ V TQ P Y II EY G L + L+ G ++ +LD + QIA GM
Sbjct: 440 LNHPNIISFKGVCTQAPCYCIIMEYCPYGQLYEVLR--DGKEIPPALVLDWSKQIASGMN 613
Query: 341 FIEERNYIHRDLRAANILVSDTLSCKIADFGLA 373
++ IHRDL++ N+LV+ KI+DFG +
Sbjct: 614 YLHSHKIIHRDLKSPNVLVAKNDVVKISDFGTS 712
>13305
Length = 549
Score = 84.3 bits (207), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 37/89 (41%), Positives = 52/89 (58%)
Frame = +2
Query: 386 GAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYR 445
+ PI+W A E++ T+T +SDVWSFG++L EI T G PY ++ L+ GYR
Sbjct: 2 STRVPIRWMAVESLFNNTYTTQSDVWSFGVVLWEIFTLGGTPYSSTDTQQLFAFLKDGYR 181
Query: 446 MVRPDNCPEELYQLMRLCWKERPEDRPTF 474
+ RP C + Y +M CW E + RPTF
Sbjct: 182 LKRPKLCDQNTYAMMLQCWNENAQRRPTF 268
>13592
Length = 980
Score = 77.8 bits (190), Expect = 9e-15, Method: Compositional matrix adjust.
Identities = 60/252 (23%), Positives = 123/252 (48%), Gaps = 17/252 (6%)
Frame = +2
Query: 237 RLGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPDAFLAEANLMKQLQ------HQRLVRL 290
++G G+FG+V+ N ++ ++K+ ++ P A N+ ++L+ H+ LVR
Sbjct: 5 KIGQGRFGKVYTAVNNNTGELM--AMKEIAIQPGETRALKNVAEELKILEGIKHKNLVRY 178
Query: 291 YAV-VTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIH 349
Y + V +E + I E G+L ++ G+ +++ AQ+ G+A + + +H
Sbjct: 179 YGIEVHREELLIFMELCSEGTLESLVELTGGLPEALSR--RFTAQLLSGVAELHKHGIVH 352
Query: 350 RDLRAANI-LVSDTLSCKIADFGLARLIEDNE--------YTAREGAKFPIKWTAPEAIN 400
RD++ ANI LV + S K+ DFG A I+ + Y + P +T +
Sbjct: 353 RDIKTANIFLVDGSNSLKLGDFGSAVKIQAHTTVPGELQGYVGTQAYMAPEVFTKTNSDG 532
Query: 401 YGTFTIKSDVWSFGILLTEIVTHGRIPYPGM-TNPEVIQNLERGYRMVRPDNCPEELYQL 459
+G +D+WS G ++ E+ + G+ P+ +N +++ + G + P++ +E +
Sbjct: 533 HGRL---ADIWSVGCVVVEMAS-GKRPWAQFDSNFQIMFKVGMGEKPQAPESLSQEGHDF 700
Query: 460 MRLCWKERPEDR 471
+ C + P+ R
Sbjct: 701 IDHCLQHDPKQR 736
>18921
Length = 697
Score = 77.4 bits (189), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 51/196 (26%), Positives = 96/196 (48%), Gaps = 3/196 (1%)
Frame = +2
Query: 228 PRETLKLVERLGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPDA--FLAEANLMKQLQHQ 285
P + ++ +LG G +G V+ + +V ++KQ + D + E ++M+Q +
Sbjct: 23 PEDVFDILGKLGEGSYGSVFKSLHKETGQVL--AIKQVPVDTDLQEIIKEISIMQQCDSK 196
Query: 286 RLVRLY-AVVTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEE 344
+V+ Y + ++I+ EY GS+ D ++ + L ++ + +G+ ++
Sbjct: 197 YIVKYYGSYFKNTDLWIVMEYCGAGSVSDIMRLRNK-TLVEREIATILYYTLKGLXYLHS 373
Query: 345 RNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTF 404
R IHRD++A NIL+++ K+ADFG+A + D P W APE I +
Sbjct: 374 RRKIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTPY-WMAPEVIQEIGY 550
Query: 405 TIKSDVWSFGILLTEI 420
+D+WS GI E+
Sbjct: 551 DCVADIWSLGITALEM 598
>12721
Length = 821
Score = 77.4 bits (189), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 46/196 (23%), Positives = 94/196 (47%), Gaps = 2/196 (1%)
Frame = +1
Query: 228 PRETLKLVERLGAGQFGEVWMGYYNGHTKVAVKSLK-QGSMSPDAFLAEANLMKQLQHQR 286
PR L ++G G G V + ++AVK + + + E +M+ H
Sbjct: 82 PRTFLDDFMKIGEGSTGIVCIATSRDGRQMAVKKMDLRKQQRRELLFNEVVVMRDYHHPN 261
Query: 287 LVRLY-AVVTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEER 345
+V +Y + + + ++++ E+ME G+L D + + ++ ++ + + +AF+
Sbjct: 262 IVEMYNSYLVNDELWVVMEFMEGGALTDIV---TNNRMDEVQIATVCRACLKALAFLHAN 432
Query: 346 NYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFT 405
IHRD+++ +IL+S K+ DFG + + + P W APE I+ +
Sbjct: 433 GVIHRDIKSDSILLSHDGKVKLXDFGFCAQVTQDLQKRKSLVGTPY-WMAPEVISRLPYG 609
Query: 406 IKSDVWSFGILLTEIV 421
+ D+WS GI++ E++
Sbjct: 610 PEVDIWSLGIMVMEMI 657
>07833
Length = 1504
Score = 77.4 bits (189), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 60/220 (27%), Positives = 108/220 (49%), Gaps = 9/220 (4%)
Frame = -3
Query: 272 FLAEANLMKQLQHQRLVRLYAVVTQEP-IYIITEYMENGSLVDFLKTPSGIKLTINKLLD 330
F+ E ++ H ++ + A Q P + +I+++M GSL + L SGI + N+ L
Sbjct: 1478 FMEEFPRLRIFNHPNVLPVLACCNQPPNLVLISQFMPFGSLYNTLHGESGIVVDQNQSLR 1299
Query: 331 MAAQIAEGMAFIE--ERNYIHRDLRAANILVSDTLSCKI--ADFGLARLIEDNEYTAREG 386
A IA GM F+ E + L + ++++ + L+ +I AD+ + +G
Sbjct: 1298 FAMDIARGMEFLHSMEPTIPNFLLTSKHVMIDEDLTARINMADYCFS--------FHEKG 1143
Query: 387 AKFPIKWTAPEAINY---GTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEV-IQNLER 442
+ W APEA+ T +D+WSF IL+ E+ T +P+ +++ EV ++
Sbjct: 1142 KVYSPAWMAPEALQRRPDDINTRAADMWSFAILMWELETR-EVPFAELSSMEVGMKVALE 966
Query: 443 GYRMVRPDNCPEELYQLMRLCWKERPEDRPTFDYLRSVLE 482
G R+ P + +L+++C E P RP FD + +LE
Sbjct: 965 GLRISIPPGISLHMSRLIKICMNEEPGKRPRFDMIIPILE 846
>01060
Length = 1800
Score = 76.3 bits (186), Expect = 3e-14, Method: Compositional matrix adjust.
Identities = 58/230 (25%), Positives = 112/230 (48%), Gaps = 6/230 (2%)
Frame = +1
Query: 224 EWEVPRETLKLVERLGAGQFGEVWMGYYNGH-TKVAVKSLK-QGSMS--PDAFLAEANLM 279
++E L +++G G +G V+ + K+A+K ++ +GS P + + E ++
Sbjct: 55 DFETALSDLTDFQKIGEGTYGVVYKCRHRATGRKLAMKKIRLRGSEDGVPSSAIREIAML 234
Query: 280 KQLQHQRLVRLYAVVTQ-EPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEG 338
++L+H +V L V+ + E ++++ E++ + K P G+ L + QI G
Sbjct: 235 RELRHTNIVCLEDVIMEDERLFLVFEFLSMDLKMYIDKFPEGVVLDRRLVKSYVFQIVTG 414
Query: 339 MAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEA 398
+ F +R +HRDL+ N+L++ T + KIADFG+AR A + + APE
Sbjct: 415 IXFCHQRRIVHRDLKPQNLLINHTGAIKIADFGMARTFA-LPVRAYTHEVVTLWYRAPEI 591
Query: 399 I-NYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMV 447
+ ++ DVWS G + +++ I P I L + +R++
Sbjct: 592 LMGASKYSTPVDVWSIGTIFADML----IRTPIFKGDSEIDQLFKIFRII 729
>29581
Length = 1278
Score = 75.5 bits (184), Expect = 4e-14, Method: Compositional matrix adjust.
Identities = 53/187 (28%), Positives = 98/187 (52%), Gaps = 10/187 (5%)
Frame = -2
Query: 262 LKQGSMSPDAFLAEANLMKQLQHQRLVRLYAVV---TQEPIYIITEYMEN--GSLVDFLK 316
L++ +SP + + L+HQ +V+L VV + + ++++ EY E SL+D +
Sbjct: 1244 LERDMVSPSVVCVRSTFLLNLRHQNIVQLQEVVVGKSLDSLFLVMEYCEQDLASLLDNMP 1065
Query: 317 TPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLI 376
P + +++ + Q+ +G+ ++ E IHRDL+ +N+L++D KIADFGLAR
Sbjct: 1064 AP----FSESQVKCIVLQLLKGLRYLHEAFIIHRDLKVSNLLMTDKGCVKIADFGLAR-- 903
Query: 377 EDNEYTAREGAKFP----IKWTAPEAI-NYGTFTIKSDVWSFGILLTEIVTHGRIPYPGM 431
Y + P + + APE + T + D+WS G +L E++ H + PG
Sbjct: 902 ---NYGKPQKPMTPKVVTLWYRAPELLFGSKTHSTAIDMWSAGCILGELLGHKPL-MPGR 735
Query: 432 TNPEVIQ 438
++ + I+
Sbjct: 734 SDLQQIE 714
>17253
Length = 483
Score = 72.8 bits (177), Expect = 3e-13, Method: Composition-based stats.
Identities = 45/153 (29%), Positives = 75/153 (49%), Gaps = 16/153 (10%)
Frame = -1
Query: 257 VAVKSLKQGSMSPDA--FLAEANLMKQL-QHQRLVRLYAVVT-QEPIYIITEYMENGSLV 312
VAVK+ + + + FL E ++M++L +H +V T +P I+ E+ +G L+
Sbjct: 459 VAVKTHNEAATDAEKSEFLRELSIMRKLPRHPNVVSFMGCCTMSDPALILMEFCCHGDLL 280
Query: 313 DFLK----------TPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDT 362
FL+ T + LT A +A GMA + +HRD+ A N+L+S+
Sbjct: 279 SFLRKRRPDRTVFLTSTANDLTARDFFSFALHVARGMAHVANNKIVHRDVAARNVLISER 100
Query: 363 LSCKIADFGLARLIEDNE--YTAREGAKFPIKW 393
CK++DFGL+R + D Y P++W
Sbjct: 99 NVCKVSDFGLSRRVGDQNDVYEIVSRRPLPLRW 1
>14126
Length = 1265
Score = 72.8 bits (177), Expect = 3e-13, Method: Compositional matrix adjust.
Identities = 54/204 (26%), Positives = 98/204 (48%), Gaps = 16/204 (7%)
Frame = +3
Query: 235 VERLGAGQFGEVW-------MGYYNGHTKVAVKSLKQGSMSPDAFLAEANLMKQLQ---H 284
V +G G +G V+ G + ++ + + ++G P + E +++KQL+ H
Sbjct: 204 VAVIGNGAYGTVYKARDLRNQGEFVAMKRIRLNNTEEGM--PMMAIREISMLKQLEQYEH 377
Query: 285 QRLVRLYAV----VTQEPIYI--ITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEG 338
+VRL V +T I + + EY+E+ K PS L +++ D+ Q+ G
Sbjct: 378 PNVVRLLDVSHNTITDREIRLNLVFEYIEHDLATYLAKCPSP-GLGPDRIKDLMLQLLNG 554
Query: 339 MAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEA 398
+ F+ +HRDL+ N+L+S K+ADFGLAR+ + + A + + +PE
Sbjct: 555 VDFLHSNRIVHRDLKPQNLLISKDGRLKLADFGLARIY--SFHMALTTVVVTLWYRSPEV 728
Query: 399 INYGTFTIKSDVWSFGILLTEIVT 422
+ + D+WS G + E+ T
Sbjct: 729 LMQAEYGTSVDIWSCGCIFAELFT 800
>01707
Length = 757
Score = 72.0 bits (175), Expect = 5e-13, Method: Compositional matrix adjust.
Identities = 56/212 (26%), Positives = 109/212 (51%), Gaps = 8/212 (3%)
Frame = +1
Query: 230 ETLKLVERLGAGQFGEVWMGYYNGHTK-VAVKSLKQGSMSP---DAFLAEANLMKQLQHQ 285
E + + ++G G +G V+ ++ VA+K + P + E ++KQL+H
Sbjct: 64 EKYEKIGKIGEGSYGVVFKCRNKETSQLVAIKKFVESEDDPLIKKIAMREIRMLKQLKHP 243
Query: 286 RLVRLYAVVTQEP-IYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEE 344
LVRL V ++ ++++ +Y+++ L + + P G+ + K + +A + F +
Sbjct: 244 NLVRLIEVFRRKKRLHLVFDYVDHTLLNELDRYPRGLPEPMVKRIIYQTLLA--VNFCHQ 417
Query: 345 RNYIHRDLRAANILVSDTLSCKIADFGLARLIE--DNEYTAREGAKFPIKWTAPEAINYG 402
N IHRD++ NIL++ K+ DFG AR++ +EYT ++ + APE +
Sbjct: 418 YNTIHRDVKPENILITRQGQVKLCDFGFARILTGPGDEYTDYVATRW---YRAPELLVGD 588
Query: 403 T-FTIKSDVWSFGILLTEIVTHGRIPYPGMTN 433
T + DVW+ G + E++T G+ +PG ++
Sbjct: 589 TQYGPPVDVWAIGCVFAELLT-GQALWPGRSD 681
>01756
Length = 1858
Score = 68.6 bits (166), Expect = 6e-12, Method: Compositional matrix adjust.
Identities = 61/232 (26%), Positives = 102/232 (43%), Gaps = 33/232 (14%)
Frame = -3
Query: 228 PRETLKL-----------VERLGAGQFGEVWMGYYN------GHTKVAVKSLKQGSMSPD 270
P ETLK + ++G G FGEV+ KV + + K+G P
Sbjct: 1781 PYETLKFPFCDEDAKYEKLAKIGQGTFGEVFKARCKKTKQVVAMKKVLMDNEKEGF--PI 1608
Query: 271 AFLAEANLMKQLQHQRLVRLYAVVTQEP---------IYIITEYMENGSLVDFLKTPSGI 321
L E +++ L H+ +V L + + + Y++ E+ E+ L L S +
Sbjct: 1607 TALREIKILQLLNHENVVDLIEICSTKATSANRYKSMFYLVFEFCEH-DLAGLLSNMSVV 1431
Query: 322 KLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLAR-----LI 376
+ ++ ++ Q+ G+ +I +HRD++AANIL++ K+ADFGLAR L
Sbjct: 1430 -FNLPEIKEVMKQLMNGLYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLR 1254
Query: 377 EDNEYTAREGAKFPIKWTAPEAINYG--TFTIKSDVWSFGILLTEIVTHGRI 426
+ N YT R W P + G ++ D W G ++ E+ T I
Sbjct: 1253 QPNRYTNR----VVTLWYRPPELLLGDRNYSTAIDQWGAGCIMAEMWTRNPI 1110
>00300
Length = 2318
Score = 68.2 bits (165), Expect = 6e-12, Method: Compositional matrix adjust.
Identities = 59/263 (22%), Positives = 117/263 (44%), Gaps = 13/263 (4%)
Frame = -1
Query: 237 RLGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPD------AFLAEANLMKQLQHQRLVRL 290
++G GQFG+V+ + + +LK+ P+ E + + +QH+ LV+
Sbjct: 1637 KIGEGQFGKVYTAV--NMSTGELMALKEMKFQPNDLQQLREMCDEIKIFEGIQHENLVKY 1464
Query: 291 YAV-VTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIH 349
Y V V ++ + + EY + G++ + K + L + +I + + E + +H
Sbjct: 1463 YGVEVHKDEMLMFMEYCDTGTIEEAAK----MGLPEYLIRRYTREIVLAVNHLHENSIVH 1296
Query: 350 RDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKF--PIKWTAPEAI---NYGTF 404
RD++ ANI ++ K+ DFG + ++ + E + APE + G +
Sbjct: 1295 RDIKGANIFLTSNGHVKLGDFGCSVKLKSHTTMPGEFHNLVGTTAYMAPEVFTQNDQGGY 1116
Query: 405 TIKSDVWSFGILLTEIVTHGRIPYPGMTNP-EVIQNLERGYRMVRPDNCPEELYQLMRLC 463
+D+WS G ++ E+ T G+ P+ + N +++ + G++ PD+ E + L
Sbjct: 1115 GRAADIWSLGCVVIEMAT-GKRPWHDLDNNYQIMYKVGIGHKPAVPDSLSVEGKHFLDLI 939
Query: 464 WKERPEDRPTFDYLRSVLEDFFT 486
P R L L+ FT
Sbjct: 938 MCHDPAQRALASQL---LDHTFT 879
>00715
Length = 1788
Score = 67.4 bits (163), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 49/172 (28%), Positives = 82/172 (47%), Gaps = 27/172 (15%)
Frame = +1
Query: 329 LDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLI------------ 376
L +A Q+A G+ ++ N +H DL+ AN L++ L +IADFG +
Sbjct: 247 LSLALQMARGLHYLHSINIVHLDLKPANCLLTRDLKLRIADFGCCHQLTPTGLDMGEREG 426
Query: 377 ----EDNEYTAREGA-----KFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIP 427
+ E T +GA + + APE + +++SDV+S GI L ++ T + P
Sbjct: 427 GMAGNELELTPVQGAWKNELAGTLAYRAPELLKGLQPSVRSDVYSLGITLWQMCTR-QGP 603
Query: 428 YPGMTNPEVI-QNLERGYRMVRPDNCPEELYQLM-----RLCWKERPEDRPT 473
Y G+ V+ Q + + R P + ++ +++M CW R EDRPT
Sbjct: 604 YEGVPAHAVVYQVVSKDLRPCPPPSTEDDPFEVMFRDLYTQCWARRVEDRPT 759
>01966
Length = 1735
Score = 65.1 bits (157), Expect = 6e-11, Method: Compositional matrix adjust.
Identities = 38/123 (30%), Positives = 71/123 (57%), Gaps = 4/123 (3%)
Frame = -1
Query: 256 KVAVKSLK-QGSMS--PDAFLAEANLMKQLQHQRLVRLYAVVTQ-EPIYIITEYMENGSL 311
K+A+K ++ +GS P + + E ++++L+H +V L V+ + E ++++ E++
Sbjct: 1630 KLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTNIVCLEDVIMEDERLFLVFEFLSMDLK 1451
Query: 312 VDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFG 371
+ K P G+ L + QI G+ F +R +HRDL+ N+L++ T + KIADFG
Sbjct: 1450 MYIDKFPEGVVLDRRLVKSYVFQIVTGINFCHQRRIVHRDLKPQNLLINHTGAIKIADFG 1271
Query: 372 LAR 374
+AR
Sbjct: 1270 MAR 1262
>14420
Length = 528
Score = 65.1 bits (157), Expect = 7e-11, Method: Compositional matrix adjust.
Identities = 39/162 (24%), Positives = 80/162 (49%), Gaps = 3/162 (1%)
Frame = +2
Query: 270 DAFLAEANLMKQLQHQRLVR-LYAVVTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKL 328
+ + E +M++ Q+ +V L + + E ++++ E++ GSL D + + ++
Sbjct: 35 ELIINEILVMRENQNPNIVNYLDSYLVGEELWVVMEFLAGGSLTDVVTETC---MDEGQI 205
Query: 329 LDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLI--EDNEYTAREG 386
+ + + + F+ E IHRD+++ NIL+ S K+ DFG + E ++ + G
Sbjct: 206 AAVCRECLQALEFLHENQVIHRDIKSDNILLGMDGSVKLTDFGFCAQLSPEQSKRSTMVG 385
Query: 387 AKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPY 428
+ W APE + + D+WS G++ E++ G PY
Sbjct: 386 TPY---WMAPEVVTRKQYGPTVDIWSLGVMCIEMI-EGEPPY 499
>27546
Length = 426
Score = 63.9 bits (154), Expect = 1e-10, Method: Composition-based stats.
Identities = 33/108 (30%), Positives = 59/108 (54%), Gaps = 1/108 (0%)
Frame = -1
Query: 272 FLAEANLMKQLQHQRLVRLYAVVTQEP-IYIITEYMENGSLVDFLKTPSGIKLTINKLLD 330
F E ++ +L H ++++++++ + P I+I Y E G ++ +K I K+
Sbjct: 339 FPRELEILTRLDHPNIIQIHSILQRGPKIFIFMRYAEKGDMLSHIKKTGPIDEAQTKVWF 160
Query: 331 MAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIED 378
Q+A+ + ++ + HRDL+ NIL+S L+ KIADFG AR D
Sbjct: 159 F--QMAKALQYLHSHDIAHRDLKCENILLSKRLNVKIADFGFARYCRD 22
>18484
Length = 635
Score = 63.5 bits (153), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 39/140 (27%), Positives = 70/140 (50%)
Frame = +1
Query: 332 AAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPI 391
AA+IA G+ F+ ++ I+RDL+ N+++ KIADFG+ + + T R P
Sbjct: 61 AAEIAVGLFFLHDQGIIYRDLKLDNVMLDSEGHIKIADFGMCKEGMTGDATTRTFCGTP- 237
Query: 392 KWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDN 451
+ APE + Y ++ D W++G+LL E++ G+ P+ G E+ ++ + + P
Sbjct: 238 DYIAPEIVLYQPYSKSVDWWAYGVLLFEMLA-GQPPFDGEDEDELFSSI-TDHNVSYPKA 411
Query: 452 CPEELYQLMRLCWKERPEDR 471
E L + + P R
Sbjct: 412 MSREAVSLCKGLLMKNPTKR 471
>12672
Length = 773
Score = 63.2 bits (152), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 43/166 (25%), Positives = 72/166 (43%), Gaps = 17/166 (10%)
Frame = +3
Query: 336 AEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPI---K 392
A G+ ++ + ++HRD++ ANIL+ + K+ DF E + A I
Sbjct: 21 ASGIQYLNDNGHVHRDIKTANILLDSEYTAKVGDFATVVSAPSGEGKTVQNASVVIGTAA 200
Query: 393 WTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIP--------------YPGMTNPEVIQ 438
+ APEAI++ T K D +SFG++L E++T G + + PE I
Sbjct: 201 YLAPEAIHFDVST-KLDSYSFGVVLLEVIT-GLVAQDYSREERTLSSHIMENVEEPEEIH 374
Query: 439 NLERGYRMVRPDNCPEELYQLMRLCWKERPEDRPTFDYLRSVLEDF 484
+ PD ++LY + C + RP +R LE+
Sbjct: 375 DFVDQSAGTWPDGAVDKLYDISMRCLNLSKKQRPNVKDIRPELEEL 512
>04591
Length = 1117
Score = 60.8 bits (146), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 42/166 (25%), Positives = 82/166 (49%), Gaps = 14/166 (8%)
Frame = -2
Query: 269 PDAFLAEANLMKQLQHQRLVRLYAVVTQEP---------IYIITEYMEN--GSLVDFLKT 317
P L E +++QL+H+ +V+L + + Y+I EY + L++ L+
Sbjct: 1089 PITALREIKILQQLEHENVVQLQEICHTQAGPYNRYKSTFYLIFEYCDYDLAGLLNNLR- 913
Query: 318 PSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLAR-LI 376
+K ++ ++ +Q+ G+ +I + +HRD++AANIL++ K+ADFGL+R +
Sbjct: 912 ---VKFSLADKKNLMSQLLNGLFYIHTKQILHRDIKAANILLTRDGVLKLADFGLSRPWV 742
Query: 377 EDNEYTAREGAKFPIKWTAPEAINYG--TFTIKSDVWSFGILLTEI 420
+ T R W P + G + + D+W G ++ E+
Sbjct: 741 KSKRLTNR----VVTLWYRPPELLLGEREYGPEIDMWGVGCIMAEM 616
>25550
Length = 941
Score = 60.5 bits (145), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 28/63 (44%), Positives = 39/63 (61%)
Frame = +3
Query: 426 IPYPGMTNPEVIQNLERGYRMVRPDNCPEELYQLMRLCWKERPEDRPTFDYLRSVLEDFF 485
+ YPG+ EV LERGYRM RP P ++Y LM CW+ P++RPTF + +LE+ F
Sbjct: 36 VXYPGVDLTEVYHLLERGYRMERPQGTPADVYILMLKCWQWDPKERPTFKEIHYLLENMF 215
Query: 486 TAT 488
+
Sbjct: 216 EKS 224
>07836
Length = 1478
Score = 59.3 bits (142), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 61/220 (27%), Positives = 105/220 (47%), Gaps = 45/220 (20%)
Frame = -1
Query: 299 IYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNY--------IHR 350
+++IT+Y ENGSL D+L + L +++L +A G+A + + HR
Sbjct: 1328 LFLITDYHENGSLHDYLLSRV---LDSSEMLALAHSAICGLAHLHIEIFGTRGKPAIAHR 1158
Query: 351 DLRAANILVSDTLSCKIADFGLA-RLI-EDNEYTA----REGAKFPIKWTAPEAI----- 399
D+++ NILV +C IAD GLA R I E NE R+G K ++ APE +
Sbjct: 1157 DIKSKNILVKKNGTCCIADLGLAVRYISESNEVDVAPNPRQGTK---RYMAPEVLEMLLN 987
Query: 400 --NYGTFTIKSDVWSFGILLTEI----VTHG-----RIPY-------PGMTNPEVIQNLE 441
N+ F ++D+++FG+++ EI V G ++P+ P + ++ +++
Sbjct: 986 VKNFDAFK-QADMYAFGLVMWEIARCCVIGGVAEEYQVPFYNCLPHDPSFEDVRLVVSVD 810
Query: 442 RGYRMVRPDN--------CPEELYQLMRLCWKERPEDRPT 473
+ VRPD + + ++M CW P R T
Sbjct: 809 K----VRPDIPLRWQEDPIMKVMVKVMCECWSGNPAARLT 702
>31885
Length = 529
Score = 57.0 bits (136), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 41/169 (24%), Positives = 76/169 (44%), Gaps = 8/169 (4%)
Frame = -2
Query: 276 ANLMKQLQHQRLVRL-YAVVTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQ 334
+++ +L H LV L YA +E ++++ + G L ++ + K Q
Sbjct: 519 VDMLTRLDHPFLVNLWYAFQDEEDLFMVVDLFLGGDLRYHMQQEVSFREDCVKF--YLCQ 346
Query: 335 IAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWT 394
+A + ++ + +HRD++ NIL+ + C + DF +A +ED+E P +
Sbjct: 345 LALVLDYLRSQKIVHRDIKPDNILLDEQGHCHVTDFNIATQLEDDELATSTSGTRP--YM 172
Query: 395 APEAINYGT-------FTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEV 436
APE YG + D WS G+ L E++ R P+ +N +
Sbjct: 171 APEV--YGVAINERRGYGFPVDWWSLGVSLFELLKKRR-PFSVHSNTSL 34
>17975
Length = 449
Score = 56.6 bits (135), Expect = 3e-08, Method: Composition-based stats.
Identities = 38/124 (30%), Positives = 65/124 (52%), Gaps = 6/124 (4%)
Frame = +3
Query: 256 KVAVKSL---KQGSMSPDAFLAEANLMKQLQHQRLVRLYAVV-TQEPIYIITEYMENGSL 311
KVAVK + K +S E MK +QH +VRLY V+ TQ +Y+I E + G +
Sbjct: 48 KVAVKVIDKTKLDEVSRSHLFQEVRCMKLVQHPNVVRLYEVIDTQTKLYLILELGDGGDM 227
Query: 312 VDF-LKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLS-CKIAD 369
D+ ++ G++ + K QI E +++ + + +HRDL+ N++ + K+ D
Sbjct: 228 YDYIMRHSGGLEEKLAK--RYFRQIVEAISYCHKLHVVHRDLKPENVVFFEKPGLVKLTD 401
Query: 370 FGLA 373
FG +
Sbjct: 402 FGFS 413
>13066
Length = 551
Score = 56.2 bits (134), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 42/172 (24%), Positives = 80/172 (46%), Gaps = 8/172 (4%)
Frame = +3
Query: 251 YNGHTKVAVKSLKQGSMSPDA----FLAEANLMKQLQHQRLVRLYAVVTQEPI-YIITEY 305
Y + K+A K + + D F E +L+ +L H ++++++++ + P +I +
Sbjct: 42 YGRNIKLACKIIDKEKAPVDFVEKFFPRELDLLTKLDHPYIIQIHSILQRXPKNFIFMRF 221
Query: 306 MENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSC 365
E G L+ +++ +K K+ Q+ + ++ + HRDL+ NIL+S +
Sbjct: 222 AERGDLLTYIQEVGFVKEKQAKI--WFYQMTTALNYLHSYDVAHRDLKCENILLSSHFNV 395
Query: 366 KIADFGL--ARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIK-SDVWSFG 414
K+ADFG A + E E + APE + + K +D WS G
Sbjct: 396 KLADFGFACACITESGEKYMSRTYCGSAAYAAPEIVYGAPYAPKVADAWSLG 551
>19094
Length = 898
Score = 55.5 bits (132), Expect = 5e-08, Method: Compositional matrix adjust.
Identities = 29/84 (34%), Positives = 45/84 (53%)
Frame = +1
Query: 337 EGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAP 396
+G+ ++ R IHRD++A NIL+++ K+ADFG+A + D P W AP
Sbjct: 91 KGL*YLHSRRKIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTP-YWMAP 267
Query: 397 EAINYGTFTIKSDVWSFGILLTEI 420
E I + +D+WS GI E+
Sbjct: 268 EVIQEIGYDCVADIWSLGITALEM 339
>09606
Length = 1300
Score = 55.1 bits (131), Expect = 7e-08, Method: Compositional matrix adjust.
Identities = 49/225 (21%), Positives = 88/225 (39%), Gaps = 22/225 (9%)
Frame = -3
Query: 230 ETLKLVERLGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPDAFLAEANLMKQLQHQRLVR 289
E L E LG G+ ++ G G + P+ + + H +V+
Sbjct: 1115 ENFVLYEELGKGEHSIIYKGRRKGTINFVAIHCIEKCKRPEV-TNTVRMTHDISHPNVVQ 939
Query: 290 LYA-VVTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYI 348
+ T ++++ E GSL D L + T + D + G+ +I +
Sbjct: 938 FHEWYETSNHLWLVVELCTGGSLADILAQDHHLPET--SIRDFGIHLVTGLHYIHSLGIL 765
Query: 349 HRDLRAANILVSDTLSCKIADFGLARLIEDNEYT-----AREGAKFPIK----------- 392
DLR + +L+ + K ADFGL+++ +N A G ++ I+
Sbjct: 764 FHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQWNIQSAEEMMKQVPT 585
Query: 393 -----WTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMT 432
+ APE +I SD+W+ G + E+ + G P+ G T
Sbjct: 584 SGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFS-GHPPFLGET 453
>03240
Length = 1683
Score = 54.3 bits (129), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 67/290 (23%), Positives = 123/290 (42%), Gaps = 61/290 (21%)
Frame = -3
Query: 235 VERLGAGQFGEVWMGYYNGHTKV-AVKSLKQGSM----SPDAFLAEANLMKQLQHQRLVR 289
++ LG G FGEV + N + A+K+L++ + AE +++ + ++ +V+
Sbjct: 1276 IKTLGVGAFGEVSLCRKNDTGMLYAMKTLRKSDVLKRNQVAHVKAERDILAEADNEWVVK 1097
Query: 290 LY-AVVTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLD------MAAQIAEGMAFI 342
LY + +Y + +Y+ G L+ L I++ I LD A++ + + +
Sbjct: 1096 LYYSFQDHNYLYFVMDYVPGGDLMGLL-----IRMEI---LDEPLARFYVAELVQAIESV 941
Query: 343 EERNYIHRDLRAANILVSDTLSCKIADFGLA---RLIEDNEYTAREGAKF---------- 389
+IHRD++ NIL+ K+ DFGL R +++Y R+G
Sbjct: 940 HRMGFIHRDIKPDNILIDRNGHIKLTDFGLCTGFRWTHNSKYYQRDGTHARQDSMEVKCQ 761
Query: 390 -----------PIK-------------------WTAPEAIN-YGTFTIKSDVWSFGILLT 418
P++ + APE ++ G +T D WS G++L
Sbjct: 760 LDEQCQCEILKPLERRRKREQRCLAHSLVGTPNYIAPEVLSRLGGYTSVCDWWSVGVILF 581
Query: 419 EIVTHGRIPY----PGMTNPEVIQNLERGYRMVRPDNCPEELYQL-MRLC 463
E++ G P+ P T +VI N + ++ R N + L +RLC
Sbjct: 580 EMLV-GHPPFYANTPAETQYKVI-NWKDMLKIPRESNLSQPAKDLILRLC 437
>30755
Length = 1137
Score = 51.2 bits (121), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 37/142 (26%), Positives = 69/142 (48%), Gaps = 2/142 (1%)
Frame = +2
Query: 332 AAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEY--TAREGAKF 389
A+I + ++ + I+RDL+ N+L+ K+ADFGL + ED Y T +
Sbjct: 50 GAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCK--EDITYGRTTKTFCGT 223
Query: 390 PIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRP 449
P ++ APE ++ + D W G+++ E++ GR+P+ + +V+ L + P
Sbjct: 224 P-EYLAPEVLDDNDYGRAVDWWGTGVVMYEMIC-GRLPFYNRDH-DVLFTLILVEDVKFP 394
Query: 450 DNCPEELYQLMRLCWKERPEDR 471
N +E L+ + P +R
Sbjct: 395 RNITDEAKSLLSGLLAKDPRNR 460
>21079
Length = 878
Score = 50.8 bits (120), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 38/137 (27%), Positives = 68/137 (49%), Gaps = 4/137 (2%)
Frame = +1
Query: 284 HQRLVRLY-AVVTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFI 342
H +L+ L+ A + ++ E++ G L + + + LT + QI G+ ++
Sbjct: 1 HPKLLMLWDAFEAPRTMVLVMEFVGAGELFERVIRDDFV-LTERDCVHFVRQICSGVGYM 177
Query: 343 EERNYIHRDLRAANIL-VSDTLS-CKIADFGLARLIE-DNEYTAREGAKFPIKWTAPEAI 399
++ +H DL+ N+L VSD + KI DFGLAR + + G ++ APE +
Sbjct: 178 HTQSILHLDLKPENVLCVSDNSNQIKIIDFGLARFYKPGDSLQVLFGTP---EFIAPEVV 348
Query: 400 NYGTFTIKSDVWSFGIL 416
NY +D+WS G++
Sbjct: 349 NYDEINFTTDMWSIGVI 399
>15910
Length = 1361
Score = 49.7 bits (117), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 34/114 (29%), Positives = 57/114 (50%), Gaps = 3/114 (2%)
Frame = +2
Query: 333 AQIAEGMAFIEERNYIHRDLRAANIL---VSDTLSCKIADFGLARLIEDNEYTAREGAKF 389
+ I G+ +I +HRDL+ N+L ++D K+ADFGL+R+IE E
Sbjct: 485 SDILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLADFGLSRIIEP-EVQMSTVCGT 661
Query: 390 PIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERG 443
P + APE + +T D+WS G+ + I+ G P+ E+ + + +G
Sbjct: 662 P-GYCAPEVLKGDKYTPSVDMWSVGV-IAYILLCGYEPFFAENEFEMYRKIIKG 817
>04138
Length = 800
Score = 49.3 bits (116), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 32/97 (32%), Positives = 47/97 (48%), Gaps = 7/97 (7%)
Frame = +1
Query: 337 EGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLAR-----LIEDNEYTAREGAKFPI 391
E + +I +HRD++AANIL++ K+ADFGLAR L + N YT R
Sbjct: 46 ERLYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNR----VVT 213
Query: 392 KWTAPEAINYG--TFTIKSDVWSFGILLTEIVTHGRI 426
W P + G ++ D W G ++ E+ T I
Sbjct: 214 LWYRPPELLLGDRNYSTAIDQWGAGCIMAEMWTRNPI 324
>13212
Length = 1067
Score = 49.3 bits (116), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 28/93 (30%), Positives = 48/93 (51%), Gaps = 7/93 (7%)
Frame = -1
Query: 334 QIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKF--PI 391
++ + F+ + IHRD++A N+L++ K+ADFG++ N T ++ F
Sbjct: 956 EMCMALDFLHRHHVIHRDIKAGNVLLTIDGEVKLADFGVSA---KNTQTQQKRDTFIGTP 786
Query: 392 KWTAPEAINYGT-----FTIKSDVWSFGILLTE 419
W APE + T + K+D+WS G+ L E
Sbjct: 785 YWMAPEVVLCETLKDTPYDFKADIWSLGVTLIE 687
>26711
Length = 405
Score = 47.4 bits (111), Expect = 1e-05, Method: Composition-based stats.
Identities = 33/111 (29%), Positives = 58/111 (52%), Gaps = 3/111 (2%)
Frame = -2
Query: 334 QIAEGMAFIEERNYIHRDLRAANILVS-DTL-SCKIADFGLAR-LIEDNEYTAREGAKFP 390
Q+ + + + + +H DL+ +N+L+S D L S ++ DFGLAR L E G
Sbjct: 392 QVLDILQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARKLYPPQETFLNHGTP-- 219
Query: 391 IKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLE 441
+T+PEA++ + SDVW G+ L I+ G+ P+ + E ++ +
Sbjct: 218 -GFTSPEALDVKPISTASDVWGVGV-LAYILLSGQSPFQADSATESLKKTQ 72
>35671
Length = 567
Score = 46.6 bits (109), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 18/47 (38%), Positives = 31/47 (65%)
Frame = -3
Query: 441 ERGYRMVRPDNCPEELYQLMRLCWKERPEDRPTFDYLRSVLEDFFTA 487
++G R+ +P +C +E Y++M CW E E+RPTF L V+E+ + +
Sbjct: 565 QKGNRLAKPISCTDEAYKVMLQCWTESREERPTFKKLVPVMENLYRS 425
>01392
Length = 1806
Score = 45.4 bits (106), Expect = 5e-05, Method: Compositional matrix adjust.
Identities = 34/115 (29%), Positives = 54/115 (46%), Gaps = 12/115 (10%)
Frame = -1
Query: 334 QIAEGMAFIEERNYIHRDLRAANIL---VSDTLSCKIADFGLARLIE-DNEYTAREGAKF 389
IA + F+ + HRDL+ NIL + D + KI DF LA I D + T
Sbjct: 1767 HIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGISCDGDGTKTPELLT 1588
Query: 390 PI---KWTAPEAINY-----GTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEV 436
P+ ++ APE ++ ++ + D+WS GI+L I+ G P+ G +
Sbjct: 1587 PVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILY-IMLCGYPPFYGQCGEDC 1426
>19761
Length = 473
Score = 45.1 bits (105), Expect = 7e-05, Method: Compositional matrix adjust.
Identities = 32/127 (25%), Positives = 61/127 (48%), Gaps = 4/127 (3%)
Frame = -3
Query: 334 QIAEGMAFIEERN--YIHRDLRAANILVSDTLSCKIADFGLARLIED--NEYTAREGAKF 389
Q A + ++ +HRDL+ NI V++ ++ D GLAR + + T++ G
Sbjct: 399 QTASALNYMHTHTPVILHRDLKPQNIYVTEKGDVRLGDLGLARKLTGPADFATSQVGT-- 226
Query: 390 PIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRP 449
I + +PE ++ + KSD+WS G + +I G+ M ++ + G ++ P
Sbjct: 225 -IMYLSPEILSQQPYNSKSDIWSLGCVFYDIT--GKKGSDEMGVMFLLVQVMGGRKLPLP 55
Query: 450 DNCPEEL 456
D+ +E
Sbjct: 54 DHYSQEF 34
>16708
Length = 1397
Score = 44.7 bits (104), Expect = 8e-05, Method: Compositional matrix adjust.
Identities = 35/151 (23%), Positives = 66/151 (43%), Gaps = 7/151 (4%)
Frame = -1
Query: 232 LKLVERLGAGQFGEVWMG-YYNGHTKVAVKSLKQGSMSPDAFLAEANLMKQLQHQRLVRL 290
+ +++ LG G FG+V+ + H K A+K+ S D A + ++
Sbjct: 1397 VAILQVLGKGVFGKVYEARLLSTHEKAALKTSILCHHSLDEVEALGRIEGGFYLAQMFGA 1218
Query: 291 YAVVTQEP-IYIITEYMENGSLVDFLKTPSGIKLTIN-----KLLDMAAQIAEGMAFIEE 344
+ P + I+ + E G L + ++ I + +A Q + I E
Sbjct: 1217 WVTCLPFPKMNILLHFYEMGPLCNVYAHYKNKEMPIRWSNPAMVCCIAGQXVCALEHIHE 1038
Query: 345 RNYIHRDLRAANILVSDTLSCKIADFGLARL 375
+H D++A N+LV +CK+ D+G+A+L
Sbjct: 1037 LGVVHMDVKADNVLVDAHGNCKLTDYGIAQL 945
>37602
Length = 804
Score = 44.7 bits (104), Expect = 8e-05, Method: Compositional matrix adjust.
Identities = 22/79 (27%), Positives = 43/79 (54%)
Frame = -1
Query: 292 AVVTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRD 351
+ + +E ++I EY GS+ D LT ++ + + +G+ ++ R +HRD
Sbjct: 315 SYLRREKLWIAMEYCGGGSMQDIYHVTG--PLTEPQIAFVCRETLKGLHYLHRRGKMHRD 142
Query: 352 LRAANILVSDTLSCKIADF 370
++ ANIL+++ K+ADF
Sbjct: 141 IKGANILLTEEGDVKLADF 85
>26560
Length = 398
Score = 44.3 bits (103), Expect = 1e-04, Method: Composition-based stats.
Identities = 29/98 (29%), Positives = 51/98 (52%), Gaps = 1/98 (1%)
Frame = -1
Query: 332 AAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPI 391
AA++ G+ + R ++RDL+ ANIL+ + +I+D GLA A G
Sbjct: 338 AAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGLACDFSKKRPHASVGTH--- 168
Query: 392 KWTAPEAINYG-TFTIKSDVWSFGILLTEIVTHGRIPY 428
+ APE + G ++ +D +SFG +L +++ G P+
Sbjct: 167 GYMAPEVLMKGQSYDSSADWFSFGCMLYKLLK-GHSPF 57
>27405
Length = 532
Score = 42.4 bits (98), Expect = 5e-04, Method: Compositional matrix adjust.
Identities = 35/121 (28%), Positives = 55/121 (45%)
Frame = -3
Query: 291 YAVVTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHR 350
YA T E + I + M G L L + G+ T ++ AA++ G+ + R ++R
Sbjct: 353 YAFQTPEKLCFILDLMNGGDLHYHL-SQHGV-FTEKEVRFYAAEVMLGLEHMHSRFVVYR 180
Query: 351 DLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDV 410
DL+ ANIL+ + +I+D GLA + A G + APE + G S
Sbjct: 179 DLKPANILLDENGHVRISDLGLACDFSKKKPHASVGTH---GYMAPEVLMKGQAYDSSAD 9
Query: 411 W 411
W
Sbjct: 8 W 6
>11185
Length = 473
Score = 42.0 bits (97), Expect = 5e-04, Method: Compositional matrix adjust.
Identities = 31/133 (23%), Positives = 56/133 (42%), Gaps = 21/133 (15%)
Frame = +1
Query: 330 DMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNE-----YTAR 384
D + G+ +I + DLR + +L+ + K ADFGL+++ +N A
Sbjct: 13 DFGIHLVTGLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAE 192
Query: 385 EGAKFPIK----------------WTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPY 428
G ++ I+ + APE +I SD+W+ G + E+ + R+
Sbjct: 193 AGDQWNIQSAEEMMKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSGSRL-- 366
Query: 429 PGMTNPEVIQNLE 441
+PE + LE
Sbjct: 367 SAKPSPEFLNLLE 405
>21433
Length = 590
Score = 42.0 bits (97), Expect = 6e-04, Method: Compositional matrix adjust.
Identities = 25/89 (28%), Positives = 41/89 (46%)
Frame = +2
Query: 334 QIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKW 393
Q++ + + R IHRD++ N+L+ KIADFG + + T G + +
Sbjct: 191 QLSSALEYCHYRKVIHRDIKPENLLLGLKGDLKIADFGWSVHAPSSRRTTMCGT---LDY 361
Query: 394 TAPEAINYGTFTIKSDVWSFGILLTEIVT 422
PE + T D+WS G+L E +
Sbjct: 362 LPPEMVEGKTHDENVDLWSLGVLCYEFLV 448
>12786
Length = 460
Score = 40.4 bits (93), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 30/108 (27%), Positives = 52/108 (48%), Gaps = 22/108 (20%)
Frame = -3
Query: 348 IHRDLRAAN-ILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPI-KWTAPEAINYGT-- 403
IH DL+ AN +LV+ L K+ DFG+A ++ ++ + + ++ + +PEAI
Sbjct: 344 IHSDLKPANFMLVAGNL--KLIDFGIANTLQQDKTSVLKDSRVGTPSYMSPEAIMAACDD 171
Query: 404 ------------------FTIKSDVWSFGILLTEIVTHGRIPYPGMTN 433
++SDVWS G +L +V +GR P+ + N
Sbjct: 170 SADDSMEEDGHRTKPKYKVGVRSDVWSLGCILYNMV-YGRTPFQHIKN 30
>18481
Length = 437
Score = 40.0 bits (92), Expect = 0.002, Method: Composition-based stats.
Identities = 20/64 (31%), Positives = 36/64 (56%), Gaps = 3/64 (4%)
Frame = -1
Query: 322 KLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCK---IADFGLARLIED 378
+ T+ +L ++ Q+ + FI ++ +IHRDL+ N L+ C I DFGL++ +D
Sbjct: 209 RFTLKTILMVSDQLLSRLEFIHQKCFIHRDLKPDNFLMGLGRHCHRLYIIDFGLSKRYKD 30
Query: 379 NEYT 382
+ T
Sbjct: 29 TQGT 18
>28638
Length = 1458
Score = 40.0 bits (92), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 31/111 (27%), Positives = 55/111 (49%), Gaps = 4/111 (3%)
Frame = -1
Query: 316 KTPSGIKLTINKLLDMAAQIAEGMAFIE--ERNYIHRDLRAANILVSD--TLSCKIADFG 371
+T G+ L + + A Q+ + F+ E N IH DL+ NIL+ + + KI DFG
Sbjct: 861 QTLEGVSLNLTR--KFAQQLCTALLFLATPEMNIIHCDLKPENILLCNPKRSAIKIVDFG 688
Query: 372 LARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVT 422
+ + Y + ++F + +PE + + + D+WS G +L E+ T
Sbjct: 687 SSCQLGQRIYQYIQ-SRF---YRSPEVLLGVPYDLAIDMWSLGCILVEMHT 547
>17286
Length = 489
Score = 39.7 bits (91), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 18/60 (30%), Positives = 35/60 (58%)
Frame = +3
Query: 44 PASPLQDNLVIALHSYEPSHDGDLGFEKGEQLRILEQSGEWWKAQSLTTGQEGFIPFNFV 103
P + ++ A++ + P DG+LGF++G+ + ++ Q E W S+ G+ G+ P N+V
Sbjct: 3 PTAGVKQPCARAIYDFLPESDGELGFQEGDMITLISQVDENWFEGSV-HGKVGYFPINYV 179
>29243
Length = 1147
Score = 39.7 bits (91), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 29/100 (29%), Positives = 47/100 (47%), Gaps = 2/100 (2%)
Frame = +2
Query: 101 NFVAKANSLEPEPWFFKNLSRKDAERQLLAPGNTHGSFLIRESES--TAGSFSLSVRDFD 158
++V + SLE W+ + R A++ L + G+FLIR + + G SLS++
Sbjct: 269 DYVNEPCSLESYNWYVGIMERPVAQKXLDTCPD--GTFLIRVTNNPLRRGELSLSIK--- 433
Query: 159 QNQGEVVKHYKIRNLDNGGFYISPRITFPGLHELVRHYTN 198
V+H K+ G FY++ F + LV HY N
Sbjct: 434 --YANAVRHIKVNRNPQGRFYLADGRYFDNIQSLVDHYEN 547
>32264
Length = 287
Score = 39.3 bits (90), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 18/45 (40%), Positives = 27/45 (60%)
Frame = +1
Query: 440 LERGYRMVRPDNCPEELYQLMRLCWKERPEDRPTFDYLRSVLEDF 484
+E GYR+ + P+ +Y+LM CW+ PE RP F L + L+D
Sbjct: 1 IEDGYRLQQNPQTPDSVYKLMLRCWEYVPEKRPHFKELYTSLKDI 135
>27287
Length = 514
Score = 37.0 bits (84), Expect = 0.017, Method: Compositional matrix adjust.
Identities = 15/43 (34%), Positives = 24/43 (55%)
Frame = -2
Query: 446 MVRPDNCPEELYQLMRLCWKERPEDRPTFDYLRSVLEDFFTAT 488
M +P E++ +M CW+E P DRP+F L L+ T++
Sbjct: 513 MKKPPYASSEMFGIMHSCWQEDPNDRPSFSRLVQELDKMLTSS 385
>36481
Length = 806
Score = 36.6 bits (83), Expect = 0.021, Method: Compositional matrix adjust.
Identities = 39/154 (25%), Positives = 66/154 (42%), Gaps = 13/154 (8%)
Frame = +2
Query: 222 EDEWEVPRET-----LKLVERLGAGQFGEV--WMGYYNGHTKVAVKSLKQGSMSPDAFLA 274
+D W R T +KL G G FG+V G +A+K +K +A
Sbjct: 323 KDIWCTMRGTSSTNDMKLCPHWGEGTFGKVVQCKDLLKG-DDIALKIIKNVDKYREAAKL 499
Query: 275 EANLMKQLQHQ------RLVRLYAVVTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKL 328
E N++++L+ + V++ I+ +M S+ DFLK S I ++
Sbjct: 500 EINVLEKLREKDPHAKHMCVQMLDWFDYHGHVCISFHMLGLSVFDFLKDNSYGAYPIEQV 679
Query: 329 LDMAAQIAEGMAFIEERNYIHRDLRAANILVSDT 362
++ Q+ + F+ E H DL+ NIL D+
Sbjct: 680 RHISYQLCYAVNFLHENQLTHTDLKPENILFVDS 781
>21210
Length = 518
Score = 36.6 bits (83), Expect = 0.021, Method: Compositional matrix adjust.
Identities = 25/85 (29%), Positives = 42/85 (49%), Gaps = 3/85 (3%)
Frame = +3
Query: 396 PEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNP-EVIQNLERGYRMVRPDN--C 452
P A ++G + ++SDVWS GI L E+ T GR PY + + +Q + RG P +
Sbjct: 42 PRASSHG-YDVRSDVWSLGITLMELAT-GRFPYRKWVSIFDQLQQVVRGVAPCLPHDGAF 215
Query: 453 PEELYQLMRLCWKERPEDRPTFDYL 477
+ + C + + RP ++ L
Sbjct: 216 SHDFVNFVNKCLTKDEKQRPKYNKL 290
>32000
Length = 644
Score = 36.2 bits (82), Expect = 0.030, Method: Compositional matrix adjust.
Identities = 30/97 (30%), Positives = 48/97 (49%), Gaps = 3/97 (3%)
Frame = -1
Query: 362 TLSCKIADFGLARL--IEDNEYTAREGAKFPIKWTAPEAINYGTF-TIKSDVWSFGILLT 418
T KIADFGLAR+ + YT + + APE + F ++ D+WS G +
Sbjct: 581 TAKMKIADFGLARVFGLPVRTYTHEV---ITLWYRAPEILLGCRFYSVPVDIWSLGCIFV 411
Query: 419 EIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDNCPEE 455
E++T R +PG + +++ YR+ R P+E
Sbjct: 410 EMMTR-RALFPGDS------EIDQLYRIFRTLGTPDE 321
>07933
Length = 728
Score = 35.8 bits (81), Expect = 0.046, Method: Compositional matrix adjust.
Identities = 14/29 (48%), Positives = 16/29 (55%)
Frame = +3
Query: 449 PDNCPEELYQLMRLCWKERPEDRPTFDYL 477
P+ CP LY +M CW P RPTF L
Sbjct: 3 PNYCPNLLYNIMMQCWSAEPSARPTFHKL 89
>38046
Length = 446
Score = 34.3 bits (77), Expect = 0.11, Method: Composition-based stats.
Identities = 14/25 (56%), Positives = 20/25 (80%)
Frame = -1
Query: 335 IAEGMAFIEERNYIHRDLRAANILV 359
IA+ MA++E+ N+IHR+L NILV
Sbjct: 98 IADAMAYMEKENFIHRNLGDRNILV 24
>20559
Length = 430
Score = 34.3 bits (77), Expect = 0.12, Method: Composition-based stats.
Identities = 21/67 (31%), Positives = 37/67 (55%), Gaps = 4/67 (5%)
Frame = -2
Query: 235 VERLGAGQFGEVWMGY-YNGHTKVAVKSLK---QGSMSPDAFLAEANLMKQLQHQRLVRL 290
+E++G G +G V+ H VA+K ++ P + L E L+K+L+H+ +VRL
Sbjct: 360 LEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHRNIVRL 181
Query: 291 YAVVTQE 297
+ V+ E
Sbjct: 180 HDVLHSE 160
>29590
Length = 320
Score = 33.9 bits (76), Expect = 0.15, Method: Composition-based stats.
Identities = 14/41 (34%), Positives = 27/41 (65%)
Frame = +3
Query: 393 WTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTN 433
+ APE ++Y +I++D+WS G+L ++T P+ G+T+
Sbjct: 72 YVAPEVLDYEPLSIQTDMWSLGVLSYVMLTACS-PFVGITS 191
>11228
Length = 2155
Score = 33.1 bits (74), Expect = 0.27, Method: Compositional matrix adjust.
Identities = 20/40 (50%), Positives = 25/40 (62%)
Frame = -1
Query: 114 WFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLS 153
W+ L R AE +LL + GS+L+RESES GSF LS
Sbjct: 1972 WYHGRLGRAGAE-ELLRDQDA-GSYLVRESESKLGSFVLS 1859
>37260
Length = 401
Score = 32.7 bits (73), Expect = 0.33, Method: Composition-based stats.
Identities = 19/69 (27%), Positives = 35/69 (50%)
Frame = -1
Query: 101 NFVAKANSLEPEPWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLSVRDFDQN 160
+F+ L+ W++ LS ++AE +L+ GSFL+R+S + SLS +
Sbjct: 221 DFLESMKQLKDCGWYWGPLSYEEAESKLM--DKRDGSFLVRDSSNENYILSLSFKSMGHV 48
Query: 161 QGEVVKHYK 169
++H+K
Sbjct: 47 HHTRIEHHK 21
>15741
Length = 402
Score = 32.3 bits (72), Expect = 0.51, Method: Composition-based stats.
Identities = 14/42 (33%), Positives = 20/42 (47%)
Frame = -3
Query: 317 TPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANIL 358
T + LT A +A GMA + +HRD+ A N+L
Sbjct: 127 TSTANDLTARDFFSFALHVARGMAHVANNKIVHRDVAARNVL 2
>06462
Length = 1511
Score = 30.8 bits (68), Expect = 1.1, Method: Compositional matrix adjust.
Identities = 30/116 (25%), Positives = 48/116 (41%), Gaps = 6/116 (5%)
Frame = +1
Query: 112 EPWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLSVRDFDQNQGEVVKHYKIR 171
E W+ +SR++AE+ L G FL+RES F LS ++ G+ + +
Sbjct: 1090 ELWYHGKMSRREAEKLL----GKDGDFLVRESGHNXSQFVLS----GKHHGQFI---HLL 1236
Query: 172 NLDNGGFYISPRITFPGLHELVRHYTN-----ASDGLCTRLSRPCQTQKPQ-KPWW 221
+D G + F + LV ++ + S G L RP P +P W
Sbjct: 1237 LVDPDGIVRTKDYIFDNISHLVSYHCHHGMPIVSHGSQLTLLRPINVSVPAYRP*W 1404
>20131
Length = 574
Score = 30.8 bits (68), Expect = 1.3, Method: Compositional matrix adjust.
Identities = 15/53 (28%), Positives = 28/53 (52%), Gaps = 1/53 (1%)
Frame = -2
Query: 54 IALHSYEPSHDGDLGFEKGEQLRILEQSGEWWKAQSLTTGQE-GFIPFNFVAK 105
+A++SY DL F +G+ + + ++ +WW T G++ G P +V K
Sbjct: 471 VAMYSYVSGETADLTFNEGDMILVTKKDEDWWTG---TLGEKTGMFPSTYVKK 322
>32357
Length = 625
Score = 30.8 bits (68), Expect = 1.4, Method: Compositional matrix adjust.
Identities = 17/52 (32%), Positives = 33/52 (63%), Gaps = 1/52 (1%)
Frame = -2
Query: 233 KLVERLGAGQFGEVWMGYYN-GHTKVAVKSLKQGSMSPDAFLAEANLMKQLQ 283
+L++++G+G FGE+++G +N +VAVK + + P + E+ L + LQ
Sbjct: 429 RLMKKIGSGSFGEIYLGVHNTSGEEVAVKLELKNAKHPQLYY-ESKLYRVLQ 277
>13664
Length = 507
Score = 30.0 bits (66), Expect = 2.1, Method: Compositional matrix adjust.
Identities = 16/56 (28%), Positives = 27/56 (48%)
Frame = +2
Query: 42 NPPASPLQDNLVIALHSYEPSHDGDLGFEKGEQLRILEQSGEWWKAQSLTTGQEGF 97
+P S + V+AL+ Y+ +L G+ + +L + E W L GQ+GF
Sbjct: 338 SPLGSTRKPKKVVALYDYKAQRSDELTILSGDVIMLLHKDSESWWMGELLDGQQGF 505
>25100
Length = 699
Score = 28.9 bits (63), Expect = 5.5, Method: Compositional matrix adjust.
Identities = 11/38 (28%), Positives = 19/38 (50%)
Frame = +3
Query: 184 ITFPGLHELVRHYTNASDGLCTRLSRPCQTQKPQKPWW 221
+T+ + L+ +T+ L + SR C+ K K WW
Sbjct: 150 LTYCSSYILIHMHTDTHKDLFLKFSRKCRENKADKIWW 263
>17516
Length = 453
Score = 28.5 bits (62), Expect = 6.0, Method: Composition-based stats.
Identities = 27/104 (25%), Positives = 50/104 (48%), Gaps = 7/104 (6%)
Frame = -3
Query: 393 WTAPEAI-NYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRM-VRPD 450
+ APE + G + +K+DV+S I+L E+ +G+ +++ + LE + +RP
Sbjct: 421 YMAPEVLLQKGQYDMKADVYSLAIILWEL-WYGQDAADHISS-HLFGRLEDAVQAGLRPS 248
Query: 451 ---NC--PEELYQLMRLCWKERPEDRPTFDYLRSVLEDFFTATE 489
C P++ +L++ W+ RPT EDF T+
Sbjct: 247 VTMTCKPPDDWLKLLQSGWEFHASKRPTSRDAAEFFEDFLERTK 116
>18050
Length = 448
Score = 28.5 bits (62), Expect = 6.2, Method: Compositional matrix adjust.
Identities = 16/57 (28%), Positives = 29/57 (50%), Gaps = 1/57 (1%)
Frame = +3
Query: 53 VIALHSYEPSHDGDLGFEKGEQLRILEQSGE-WWKAQSLTTGQEGFIPFNFVAKANS 108
VIA HSYE L E G+ + + + + W++ + + G G+ P ++ + NS
Sbjct: 24 VIAKHSYESDEPDVLQLELGDVVNVSRKLPDGWYQGERIRDGAVGWFPGSYTEELNS 194
>30665
Length = 530
Score = 28.5 bits (62), Expect = 7.1, Method: Compositional matrix adjust.
Identities = 10/19 (52%), Positives = 17/19 (89%)
Frame = +3
Query: 299 IYIITEYMENGSLVDFLKT 317
++++TE+ ENGSL D+LK+
Sbjct: 441 LWLLTEFHENGSLSDYLKS 497
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000264235 | hsapiens_gene_ensembl | Glycogen
synthase kinase-3 beta (EC 2.7.11.26) (GSK-3 beta).
[Source:Uniprot/SWISSPROT;Acc:P49841]
(420 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
32359 244 2e-80
05084 217 7e-57
01707 155 2e-38
01060 138 5e-33
14126 136 1e-32
29581 118 5e-27
01756 117 6e-27
04591 103 1e-22
28638 75 4e-22
04138 99 3e-21
13592 93 2e-19
32000 89 3e-18
03508 89 3e-18
00300 85 4e-17
23319 79 4e-15
18921 77 1e-14
12721 77 2e-14
03240 75 5e-14
09606 73 2e-13
15910 71 9e-13
13066 70 1e-12
12453 68 6e-12
18484 68 6e-12
06405 68 7e-12
30755 67 1e-11
19301 66 3e-11
01966 65 5e-11
09007 64 9e-11
26560 64 1e-10
14116 62 3e-10
31885 62 4e-10
12786 62 6e-10
01718 61 1e-09
18287 60 1e-09
01392 60 2e-09
13212 59 3e-09
14420 59 5e-09
03294 57 9e-09
31489 57 1e-08
27546 56 3e-08
17975 55 7e-08
27405 54 2e-07
18401 54 2e-07
26711 52 4e-07
07940 52 4e-07
11185 52 7e-07
19761 51 7e-07
19094 51 8e-07
21433 50 2e-06
14477 49 3e-06
00715 49 5e-06
04852 47 1e-05
28157 47 2e-05
21808 47 2e-05
11404 45 5e-05
21079 45 7e-05
12672 44 1e-04
16708 42 3e-04
07291 40 0.001
00638 40 0.002
36481 40 0.002
16003 39 0.003
26009 38 0.006
25019 38 0.010
21800 38 0.010
01106 38 0.010
29360 36 0.030
13078 35 0.039
02638 35 0.060
00486 34 0.12
20152 33 0.15
37602 33 0.20
18481 32 0.44
35032 32 0.65
38560 31 1.0
19248 30 1.6
32357 30 1.6
24241 30 1.8
19149 28 5.1
32957 28 6.5
26052 28 7.5
>32359
Length = 928
Score = 244 bits (624), Expect(3) = 2e-80, Method: Compositional matrix adjust.
Identities = 113/131 (86%), Positives = 126/131 (96%)
Frame = -1
Query: 44 PGQGPDRPQEVSYTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRELQIMRK 103
GQGPDRPQEVSYTD KVIGNGSFGVVYQAKL D+ ELVAIKKVLQDKRFKNRELQIMRK
Sbjct: 460 SGQGPDRPQEVSYTDAKVIGNGSFGVVYQAKLVDTSELVAIKKVLQDKRFKNRELQIMRK 281
Query: 104 LDHCNIVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMY 163
L+H NIV+L++FFYSSGEKKDEV+LNLVL+YVPETVYRVARHYS++KQT+P++Y+KLYMY
Sbjct: 280 LEHQNIVKLKFFFYSSGEKKDEVFLNLVLEYVPETVYRVARHYSKSKQTIPILYIKLYMY 101
Query: 164 QLFRSLAYIHS 174
QLFRSLAYIHS
Sbjct: 100 QLFRSLAYIHS 68
Score = 49.7 bits (117), Expect(3) = 2e-80, Method: Compositional matrix adjust.
Identities = 28/43 (65%), Positives = 31/43 (72%)
Frame = -2
Query: 1 MSGRPRTTSFAESCKPVQQPSAFGSMKVSRDKDGSKVTTVVAT 43
MSGRPRTTSFAE KP Q + FG M+ KDG KVTTV+AT
Sbjct: 582 MSGRPRTTSFAEGGKPGQN-APFGGMRTI-SKDGGKVTTVLAT 460
Score = 44.3 bits (103), Expect(3) = 2e-80, Method: Compositional matrix adjust.
Identities = 18/21 (85%), Positives = 20/21 (95%)
Frame = -3
Query: 176 GICHRDIKPQNLLLDPDTAVL 196
G+CHRDIKPQNLLLDP+T VL
Sbjct: 65 GVCHRDIKPQNLLLDPETGVL 3
>05084
Length = 1324
Score = 217 bits (553), Expect = 7e-57, Method: Compositional matrix adjust.
Identities = 102/127 (80%), Positives = 111/127 (87%)
Frame = +2
Query: 257 FPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHPWTKVFRPRTPPEAIAL 316
PGDSGVDQLVEIIKVLGTPTREQIREMNPNY+EFKFPQIKAHPWTKVFRPRTPPEAI L
Sbjct: 2 LPGDSGVDQLVEIIKVLGTPTREQIREMNPNYSEFKFPQIKAHPWTKVFRPRTPPEAIQL 181
Query: 317 CSRLLEYTPTARLTPLEACAHSFFDELRDPNVKLPNGRDTPALFNFTTQELSSNPPLATI 376
SRLLEYTP+AR+ P+EACAH+FFDELRDP +LPNGR+ P LF+FT EL+ P L
Sbjct: 182 VSRLLEYTPSARIQPMEACAHAFFDELRDPASRLPNGRELPPLFSFTQMELAIAPQLNAS 361
Query: 377 LIPPHAR 383
LIPPHAR
Sbjct: 362 LIPPHAR 382
>01707
Length = 757
Score = 155 bits (393), Expect = 2e-38, Method: Compositional matrix adjust.
Identities = 91/227 (40%), Positives = 131/227 (57%), Gaps = 7/227 (3%)
Frame = +1
Query: 55 SYTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQD------KRFKNRELQIMRKLDHCN 108
Y IG GS+GVV++ + ++ +LVAIKK ++ K+ RE++++++L H N
Sbjct: 67 KYEKIGKIGEGSYGVVFKCRNKETSQLVAIKKFVESEDDPLIKKIAMREIRMLKQLKHPN 246
Query: 109 IVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRS 168
+VRL F + + L+LV DYV T+ Y R LP VK +YQ +
Sbjct: 247 LVRLIEVF------RRKKRLHLVFDYVDHTLLNELDRYPRG---LPEPMVKRIIYQTLLA 399
Query: 169 LAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVR-GEPNVSYICSRYYRAPEL 227
+ + H + HRD+KP+N+L+ V KLCDFG A+ L G+ Y+ +R+YRAPEL
Sbjct: 400 VNFCHQYNTIHRDVKPENILITRQGQV-KLCDFGFARILTGPGDEYTDYVATRWYRAPEL 576
Query: 228 IFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLG 274
+ G T Y +DVW+ GCV AELL GQ ++PG S VDQL I K LG
Sbjct: 577 LVGDTQYGPPVDVWAIGCVFAELLTGQALWPGRSDVDQLHLIRKTLG 717
>01060
Length = 1800
Score = 138 bits (347), Expect = 5e-33, Method: Compositional matrix adjust.
Identities = 96/307 (31%), Positives = 154/307 (50%), Gaps = 23/307 (7%)
Frame = +1
Query: 57 TDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKN----------RELQIMRKLDH 106
TD + IG G++GVVY+ + +G +A+KK+ R + RE+ ++R+L H
Sbjct: 82 TDFQKIGEGTYGVVYKCRHRATGRKLAMKKI----RLRGSEDGVPSSAIREIAMLRELRH 249
Query: 107 CNIVRL--------RYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYV 158
NIV L R F D L + +D PE V R V
Sbjct: 250 TNIVCLEDVIMEDERLFLVFEFLSMD---LKMYIDKFPEGVVLDRR------------LV 384
Query: 159 KLYMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSY-- 216
K Y++Q+ + + H I HRD+KPQNLL++ T +K+ DFG A+ P +Y
Sbjct: 385 KSYVFQIVTGIXFCHQRRIVHRDLKPQNLLIN-HTGAIKIADFGMARTF--ALPVRAYTH 555
Query: 217 -ICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGT 275
+ + +YRAPE++ GA+ Y++ +DVWS G + A++L+ PIF GDS +DQL +I +++GT
Sbjct: 556 EVVTLWYRAPEILMGASKYSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGT 735
Query: 276 PTREQIREMN--PNYTEFKFPQIKAHPWTKVFRPRTPPEAIALCSRLLEYTPTARLTPLE 333
PT + E + P + FP K ++ + L R L+ P R++ +
Sbjct: 736 PTEQTWPEFHKLPAFNGM-FPLWKEGKLSETLTD-LDSLGLDLIERTLKCDPAQRISCKK 909
Query: 334 ACAHSFF 340
H++F
Sbjct: 910 MLQHAYF 930
>14126
Length = 1265
Score = 136 bits (343), Expect = 1e-32, Method: Compositional matrix adjust.
Identities = 107/351 (30%), Positives = 175/351 (49%), Gaps = 17/351 (4%)
Frame = +3
Query: 12 ESCKPVQQPSAFGSMKVSRDKDGSKVTTVVATPGQGPDRPQEVSYTDTKVIGNGSFGVVY 71
E P P A SMK + G + A E Y + VIGNG++G VY
Sbjct: 66 EESSPKTSP-AVRSMKTAISPKGRDGQSESAAKMSRRRDSTEQKYEEVAVIGNGAYGTVY 242
Query: 72 QAK-LCDSGELVAIKKVLQDKRFKN----------RELQIMRKLD---HCNIVRLRYFFY 117
+A+ L + GE VA+K++ R N RE+ ++++L+ H N+VRL +
Sbjct: 243 KARDLRNQGEFVAMKRI----RLNNTEEGMPMMAIREISMLKQLEQYEHPNVVRLLDVSH 410
Query: 118 SSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQ-TLPVIYVKLYMYQLFRSLAYIHSFG 176
++ + E+ LNLV +Y+ + +A + ++ L +K M QL + ++HS
Sbjct: 411 NTITDR-EIRLNLVFEYIE---HDLATYLAKCPSPGLGPDRIKDLMLQLLNGVDFLHSNR 578
Query: 177 ICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTS 236
I HRD+KPQNLL+ D LKL DFG A+ + + + +YR+PE++ A +Y +
Sbjct: 579 IVHRDLKPQNLLISKD-GRLKLADFGLARIYSFHMALTTVVVTLWYRSPEVLMQA-EYGT 752
Query: 237 SIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIRE-MNPNYTEFK-FP 294
S+D+WS GC+ AEL + +F G S DQL +I +V+G P E ++ + F+ P
Sbjct: 753 SVDIWSCGCIFAELFTRRALFKGSSEFDQLKKIFEVIGLPPAGDWPEGVSVHRNSFRPTP 932
Query: 295 QIKAHPWTKVFRPRTPPEAIALCSRLLEYTPTARLTPLEACAHSFFDELRD 345
+ + P P+A L ++L + R++ E+ H + LRD
Sbjct: 933 PVP----LQTLVPEMDPQAKDLMEKMLVFKSGRRISSRESLLHPY---LRD 1064
>29581
Length = 1278
Score = 118 bits (295), Expect = 5e-27, Method: Compositional matrix adjust.
Identities = 80/253 (31%), Positives = 133/253 (52%), Gaps = 10/253 (3%)
Frame = -2
Query: 100 IMRKLDHCNIVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARH----YSRAKQTLPV 155
+ L H NIV+L+ G+ D ++L V++Y + + + + +S ++
Sbjct: 1196 FLLNLRHQNIVQLQEVVV--GKSLDSLFL--VMEYCEQDLASLLDNMPAPFSESQ----- 1044
Query: 156 IYVKLYMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGE-PNV 214
VK + QL + L Y+H I HRD+K NLL+ D +K+ DFG A+ + + P
Sbjct: 1043 --VKCIVLQLLKGLRYLHEAFIIHRDLKVSNLLMT-DKGCVKIADFGLARNYGKPQKPMT 873
Query: 215 SYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLG 274
+ + +YRAPEL+FG+ ++++ID+WSAGC+L ELL +P+ PG S + Q+ I+++LG
Sbjct: 872 PKVVTLWYRAPELLFGSKTHSTAIDMWSAGCILGELLGHKPLMPGRSDLQQIELIMELLG 693
Query: 275 TPTREQIREMNPNYTEF-KFPQ--IKAHPWTKVFR--PRTPPEAIALCSRLLEYTPTARL 329
TP + P +++ F Q +K P+ + P I L + L Y P R
Sbjct: 692 TPN----DTIWPGFSQLPAFEQFTLKKQPYNNLRHTFPWLSESGIRLLNGLFMYHPQKRA 525
Query: 330 TPLEACAHSFFDE 342
T + HS+F E
Sbjct: 524 TAEDCLEHSYFKE 486
>01756
Length = 1858
Score = 117 bits (294), Expect = 6e-27, Method: Compositional matrix adjust.
Identities = 76/240 (31%), Positives = 124/240 (51%), Gaps = 12/240 (5%)
Frame = -3
Query: 52 QEVSYTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKN------RELQIMRKLD 105
++ Y IG G+FG V++A+ + ++VA+KKVL D + RE++I++ L+
Sbjct: 1748 EDAKYEKLAKIGQGTFGEVFKARCKKTKQVVAMKKVLMDNEKEGFPITALREIKILQLLN 1569
Query: 106 HCNIVRLRYFFYSSGEKKD--EVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMY 163
H N+V L + + + LV ++ + +A S + +K M
Sbjct: 1568 HENVVDLIEICSTKATSANRYKSMFYLVFEFCE---HDLAGLLSNMSVVFNLPEIKEVMK 1398
Query: 164 QLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRG--EPN--VSYICS 219
QL L YIH I HRD+K N+L+ VLKL DFG A+ +PN + + +
Sbjct: 1397 QLMNGLYYIHRNKILHRDMKAANILITKQ-GVLKLADFGLARAFSVNLRQPNRYTNRVVT 1221
Query: 220 RYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTRE 279
+YR PEL+ G +Y+++ID W AGC++AE+ PI G + +QL I ++ G+ T E
Sbjct: 1220 LWYRPPELLLGDRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQNQLTLITQLCGSITPE 1041
>04591
Length = 1117
Score = 103 bits (258), Expect = 1e-22, Method: Compositional matrix adjust.
Identities = 75/252 (29%), Positives = 118/252 (46%), Gaps = 7/252 (2%)
Frame = -2
Query: 96 RELQIMRKLDHCNIVRLRYFFYSSG----EKKDEVYLNLVLDYVPETVYRVARHYSRAKQ 151
RE++I+++L+H N+V+L+ ++ K YL + +Y Y +A + +
Sbjct: 1074 REIKILQQLEHENVVQLQEICHTQAGPYNRYKSTFYL--IFEYCD---YDLAGLLNNLRV 910
Query: 152 TLPVIYVKLYMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGE 211
+ K M QL L YIH+ I HRDIK N+LL D VLKL DFG ++ V+ +
Sbjct: 909 KFSLADKKNLMSQLLNGLFYIHTKQILHRDIKAANILLTRD-GVLKLADFGLSRPWVKSK 733
Query: 212 PNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIK 271
+ + + +YR PEL+ G +Y ID+W GC++AE+ +P+ G S QL I
Sbjct: 732 RLTNRVVTLWYRPPELLLGEREYGPEIDMWGVGCIMAEMWSRKPLMQGRSEQHQLSLITD 553
Query: 272 VLGTPTREQIREMN--PNYTEFKFPQIKAHPWT-KVFRPRTPPEAIALCSRLLEYTPTAR 328
+ G+ E + Y + PQ K ++ E L L P R
Sbjct: 552 LCGSLNAEVWPGVTKLELYGKLDLPQGKPRKVKERMLDLLKNKEGAELIDIFLRLDPGQR 373
Query: 329 LTPLEACAHSFF 340
+ A +H FF
Sbjct: 372 MNCDNALSHDFF 337
>28638
Length = 1458
Score = 75.5 bits (184), Expect(3) = 4e-22, Method: Compositional matrix adjust.
Identities = 45/113 (39%), Positives = 70/113 (61%), Gaps = 6/113 (5%)
Frame = -1
Query: 149 AKQTLPVIYVKL---YMYQLFRSLAYIHS--FGICHRDIKPQNLLL-DPDTAVLKLCDFG 202
A QTL + + L + QL +L ++ + I H D+KP+N+LL +P + +K+ DFG
Sbjct: 867 ATQTLEGVSLNLTRKFAQQLCTALLFLATPEMNIIHCDLKPENILLCNPKRSAIKIVDFG 688
Query: 203 SAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQP 255
S+ QL G+ YI SR+YR+PE++ G Y +ID+WS GC+L E+ G+P
Sbjct: 687 SSCQL--GQRIYQYIQSRFYRSPEVLLGV-PYDLAIDMWSLGCILVEMHTGEP 538
Score = 34.3 bits (77), Expect(3) = 4e-22, Method: Compositional matrix adjust.
Identities = 32/129 (24%), Positives = 53/129 (41%), Gaps = 36/129 (27%)
Frame = -2
Query: 253 GQPIFPGDSGVDQLVEIIKVLGTPTREQIREMN---------PNYT----------EFKF 293
G P+F G + DQ+++I++VLG P R + + P+ T ++K
Sbjct: 545 GNPLFAGSNEFDQMMKIVEVLGVPPRHILDQAQKTRKYFDLLPDGTYAPKKPRDNKKYKS 366
Query: 294 PQI----------KAHPWTKVFRPRTPPEAIA-------LCSRLLEYTPTARLTPLEACA 336
P K P + R P +A L R+L++ P R++P A
Sbjct: 365 PSSRKLHEVLGAEKGGPGGR--RMGEPGHTVADYLKFKDLILRMLDFDPKTRISPYYALQ 192
Query: 337 HSFFDELRD 345
H+FF + D
Sbjct: 191 HNFFRKTSD 165
Score = 32.7 bits (73), Expect(3) = 4e-22, Method: Compositional matrix adjust.
Identities = 32/99 (32%), Positives = 47/99 (47%), Gaps = 10/99 (10%)
Frame = -3
Query: 56 YTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRE------LQIMRKLDHCN- 108
Y +IG GSFG V +A E VAIK + K F N+ L++M + D N
Sbjct: 1141 YEIDSLIGKGSFGQVVKAYDHGDQEQVAIKIIKNKKPFLNQAQIEVKLLELMNRHDADNX 962
Query: 109 --IVRL-RYFFYSSGEKKDEVYLNLVLDYVPETVYRVAR 144
IVRL R+F + + +L LV + + +Y + R
Sbjct: 961 YYIVRLKRHFMFRN-------HLCLVFELLSYNLYDLLR 866
>04138
Length = 800
Score = 99.0 bits (245), Expect = 3e-21, Method: Compositional matrix adjust.
Identities = 65/185 (35%), Positives = 96/185 (51%), Gaps = 13/185 (7%)
Frame = +1
Query: 169 LAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRG--EPN--VSYICSRYYRA 224
L YIH I HRD+K N+L+ VLKL DFG A+ +PN + + + +YR
Sbjct: 52 LYYIHRNKILHRDMKAANILITKQ-GVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRP 228
Query: 225 PELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREM 284
PEL+ G +Y+++ID W AGC++AE+ PI G + +QL I ++ G+ T E+
Sbjct: 229 PELLLGDRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQNQLTLITQLCGSIT----PEV 396
Query: 285 NPNYTEFK-FPQIK---AHPWTKVFRPR-----TPPEAIALCSRLLEYTPTARLTPLEAC 335
P T+ + QIK A + R R P + L RLL+ P+ R++ EA
Sbjct: 397 WPGVTQLSMYHQIKGALAAGRKNIIRDRFARILKDPYGLDLFERLLKMDPSQRISADEAL 576
Query: 336 AHSFF 340
H FF
Sbjct: 577 NHDFF 591
>13592
Length = 980
Score = 92.8 bits (229), Expect = 2e-19, Method: Compositional matrix adjust.
Identities = 66/207 (31%), Positives = 106/207 (51%), Gaps = 14/207 (6%)
Frame = +2
Query: 62 IGNGSFGVVYQAKLCDSGELVAIKKVL----QDKRFKN--RELQIMRKLDHCNIVRLRYF 115
IG G FG VY A ++GEL+A+K++ + + KN EL+I+ + H N+VR Y+
Sbjct: 8 IGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETRALKNVAEELKILEGIKHKNLVR--YY 181
Query: 116 FYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSF 175
++ +++ L + E++ + LP + + QL +A +H
Sbjct: 182 GIEVHREELLIFMELCSEGTLESLVELT-------GGLPEALSRRFTAQLLSGVAELHKH 340
Query: 176 GICHRDIKPQNLLLDPDTAVLKLCDFGSAKQL-----VRGEPNVSYICSRYYRAPELIFG 230
GI HRDIK N+ L + LKL DFGSA ++ V GE Y+ ++ Y APE +F
Sbjct: 341 GIVHRDIKTANIFLVDGSNSLKLGDFGSAVKIQAHTTVPGELQ-GYVGTQAYMAPE-VFT 514
Query: 231 ATD---YTSSIDVWSAGCVLAELLLGQ 254
T+ + D+WS GCV+ E+ G+
Sbjct: 515 KTNSDGHGRLADIWSVGCVVVEMASGK 595
>32000
Length = 644
Score = 89.4 bits (220), Expect = 3e-18, Method: Compositional matrix adjust.
Identities = 49/161 (30%), Positives = 87/161 (54%), Gaps = 9/161 (5%)
Frame = -1
Query: 193 TAVLKLCDFGSAKQLVRGEPNVSY---ICSRYYRAPELIFGATDYTSSIDVWSAGCVLAE 249
TA +K+ DFG A+ V G P +Y + + +YRAPE++ G Y+ +D+WS GC+ E
Sbjct: 581 TAKMKIADFGLAR--VFGLPVRTYTHEVITLWYRAPEILLGCRFYSVPVDIWSLGCIFVE 408
Query: 250 LLLGQPIFPGDSGVDQLVEIIKVLGTPTRE------QIREMNPNYTEFKFPQIKAHPWTK 303
++ + +FPGDS +DQL I + LGTP + ++ + P + ++ ++ T
Sbjct: 407 MMTRRALFPGDSEIDQLYRIFRTLGTPDEKVWPGVSKLPDYKPTFPKWPLKNLE----TV 240
Query: 304 VFRPRTPPEAIALCSRLLEYTPTARLTPLEACAHSFFDELR 344
V + + L R+L Y P R++ A H +F++++
Sbjct: 239 VSLSKV---GLDLLKRMLTYNPNRRISARSAMRHPYFNDMK 126
>03508
Length = 1463
Score = 89.0 bits (219), Expect = 3e-18, Method: Compositional matrix adjust.
Identities = 42/115 (36%), Positives = 70/115 (60%), Gaps = 2/115 (1%)
Frame = +1
Query: 146 YSRAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAK 205
+ + QT ++ Y+Y+L ++L + HS GI HRD+KP N+++D + L+L D+G A+
Sbjct: 841 FKQLYQTFTDYDIRFYLYELMKALDFCHSMGIMHRDVKPHNVMIDHENKKLRLIDWGLAE 1020
Query: 206 QLVRG-EPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLL-GQPIFP 258
G E NV + SRY++ PEL+ Y S+D+WS GC+ A ++ +P+ P
Sbjct: 1021FYHPGMEYNVR-VASRYFKGPELLLDYQMYDYSLDMWSLGCMFASMIFRKEPLLP 1182
Score = 44.7 bits (104), Expect = 7e-05, Method: Compositional matrix adjust.
Identities = 35/111 (31%), Positives = 48/111 (43%), Gaps = 10/111 (9%)
Frame = +2
Query: 240 VWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTP------TREQIREMNPNYTEFKF 293
VW+A C+ A P F G DQLV I KVLGT + QI +++P + +
Sbjct: 1130 VWAA-CLPA*SSGKSPFFHGHDNYDQLVRIAKVLGTDDLYGYIEKYQI-DLDPRFNDI-L 1300
Query: 294 PQIKAHPWTKVFRPRT----PPEAIALCSRLLEYTPTARLTPLEACAHSFF 340
+ W + PEA+ +LL Y RLT EA H +F
Sbjct: 1301 GRHSRKRWERFVHSENQHLISPEALDFLDKLLRYDHNERLTAREAMDHPYF 1453
>00300
Length = 2318
Score = 85.1 bits (209), Expect = 4e-17, Method: Compositional matrix adjust.
Identities = 72/242 (29%), Positives = 116/242 (47%), Gaps = 19/242 (7%)
Frame = -1
Query: 32 KDGSKVTTVVATPGQGPD-----RPQEVSYTDTKVIGNGSFGVVYQAKLCDSGELVAIKK 86
++ S++ V A P + PD R + IG G FG VY A +GEL+A+K+
Sbjct: 1736 QEKSRIGRVAAKPRE-PDYRINVRRVNFRWQRGNKIGEGQFGKVYTAVNMSTGELMALKE 1560
Query: 87 V------LQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSGEKKDEVYLNLVLDYVPETVY 140
+ LQ R E++I + H N+V+ +Y KDE+ + ++Y
Sbjct: 1559 MKFQPNDLQQLREMCDEIKIFEGIQHENLVK----YYGVEVHKDEMLM--FMEYCDTGTI 1398
Query: 141 RVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCD 200
A AK LP ++ Y ++ ++ ++H I HRDIK N+ L + V KL D
Sbjct: 1397 EEA-----AKMGLPEYLIRRYTREIVLAVNHLHENSIVHRDIKGANIFLTSNGHV-KLGD 1236
Query: 201 FGSAKQL-----VRGEPNVSYICSRYYRAPELIFGATD---YTSSIDVWSAGCVLAELLL 252
FG + +L + GE + + + + Y APE +F D Y + D+WS GCV+ E+
Sbjct: 1235 FGCSVKLKSHTTMPGEFH-NLVGTTAYMAPE-VFTQNDQGGYGRAADIWSLGCVVIEMAT 1062
Query: 253 GQ 254
G+
Sbjct: 1061 GK 1056
>23319
Length = 2235
Score = 78.6 bits (192), Expect = 4e-15, Method: Compositional matrix adjust.
Identities = 47/119 (39%), Positives = 67/119 (56%), Gaps = 3/119 (2%)
Frame = +3
Query: 228 IFGATDYTSSIDVWSAGCVLAELL-LGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMN- 285
++ A Y++SID+WSAGC+ AEL G+P+FPG+ DQL I K+LGTPT +Q M
Sbjct: 9 VYXAKMYSTSIDMWSAGCIFAELANAGRPLFPGNDDDDQLKRIFKLLGTPTEDQWPGMTQ 188
Query: 286 -PNYTEFKFPQIKAHPWTKVFRPRTPPEAIALCSRLLEYTPTARLTPLEACAHSFFDEL 343
PNY F + W +V P+ + L LL P+ R++ EA H +F +L
Sbjct: 189 LPNYRMFPMYHVTTT-WQQVV-PKLNSKGRDLLQCLLVCCPSDRMSADEALQHPYFADL 359
>18921
Length = 697
Score = 77.0 bits (188), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 64/210 (30%), Positives = 107/210 (50%), Gaps = 4/210 (1%)
Frame = +2
Query: 50 RPQEVSYTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKN--RELQIMRKLDHC 107
RP E + +G GS+G V+++ ++G+++AIK+V D + +E+ IM++ D
Sbjct: 17 RPPEDVFDILGKLGEGSYGSVFKSLHKETGQVLAIKQVPVDTDLQEIIKEISIMQQCDSK 196
Query: 108 NIVRLRYFFYSSGEKKDEVYLNLVLDYV-PETVYRVARHYSRAKQTLPVIYVKLYMYQLF 166
IV+ +Y S K ++++ V++Y +V + R ++ TL + +Y
Sbjct: 197 YIVK----YYGSYFKNTDLWI--VMEYCGAGSVSDIMRLRNK---TLVEREIATILYYTL 349
Query: 167 RSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRG-EPNVSYICSRYYRAP 225
+ L Y+HS HRDIK N+LL+ + KL DFG A QL + I + Y+ AP
Sbjct: 350 KGLXYLHSRRKIHRDIKAGNILLNNEGHA-KLADFGVAGQLTDTMAKRNTVIGTPYWMAP 526
Query: 226 ELIFGATDYTSSIDVWSAGCVLAELLLGQP 255
E+I Y D+WS G E+ G+P
Sbjct: 527 EVI-QEIGYDCVADIWSLGITALEMAEGKP 613
>12721
Length = 821
Score = 76.6 bits (187), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 62/207 (29%), Positives = 104/207 (50%), Gaps = 7/207 (3%)
Frame = +1
Query: 58 DTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNR------ELQIMRKLDHCNIVR 111
D IG GS G+V A D G +A+KK+ D R + R E+ +MR H NIV
Sbjct: 100 DFMKIGEGSTGIVCIATSRD-GRQMAVKKM--DLRKQQRRELLFNEVVVMRDYHHPNIVE 270
Query: 112 LRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAY 171
+ Y+S DE+++ V++++ +R + + + ++LA+
Sbjct: 271 M----YNSYLVNDELWV--VMEFMEGGALTDIVTNNRMDE----VQIATVCRACLKALAF 420
Query: 172 IHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRG-EPNVSYICSRYYRAPELIFG 230
+H+ G+ HRDIK ++LL D V KL DFG Q+ + + S + + Y+ APE+I
Sbjct: 421 LHANGVIHRDIKSDSILLSHDGKV-KLXDFGFCAQVTQDLQKRKSLVGTPYWMAPEVI-S 594
Query: 231 ATDYTSSIDVWSAGCVLAELLLGQPIF 257
Y +D+WS G ++ E++ +P F
Sbjct: 595 RLPYGPEVDIWSLGIMVMEMIDAEPPF 675
>03240
Length = 1683
Score = 75.1 bits (183), Expect = 5e-14, Method: Compositional matrix adjust.
Identities = 68/269 (25%), Positives = 113/269 (42%), Gaps = 54/269 (20%)
Frame = -3
Query: 56 YTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNR-------ELQIMRKLDHCN 108
+ K +G G+FG V + D+G L A+K + + K E I+ + D+
Sbjct: 1285 FEKIKTLGVGAFGEVSLCRKNDTGMLYAMKTLRKSDVLKRNQVAHVKAERDILAEADNEW 1106
Query: 109 IVRLRYFFYSSGEKKDEVYLNLVLDYVP--ETVYRVARHYSRAKQTLPVIYVKLYMYQLF 166
+V+L Y F +D YL V+DYVP + + + R + L + Y+ +L
Sbjct: 1105 VVKLYYSF------QDHNYLYFVMDYVPGGDLMGLLIR-----MEILDEPLARFYVAELV 959
Query: 167 RSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFG---------SAKQLVRGEPNV--- 214
+++ +H G HRDIKP N+L+D + + KL DFG ++K R +
Sbjct: 958 QAIESVHRMGFIHRDIKPDNILIDRNGHI-KLTDFGLCTGFRWTHNSKYYQRDGTHARQD 782
Query: 215 ---------------------------------SYICSRYYRAPELIFGATDYTSSIDVW 241
S + + Y APE++ YTS D W
Sbjct: 781 SMEVKCQLDEQCQCEILKPLERRRKREQRCLAHSLVGTPNYIAPEVLSRLGGYTSVCDWW 602
Query: 242 SAGCVLAELLLGQPIFPGDSGVDQLVEII 270
S G +L E+L+G P F ++ + ++I
Sbjct: 601 SVGVILFEMLVGHPPFYANTPAETQYKVI 515
>09606
Length = 1300
Score = 72.8 bits (177), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 76/306 (24%), Positives = 131/306 (42%), Gaps = 27/306 (8%)
Frame = -3
Query: 62 IGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFK-NRELQIMRKLDHCNIVRLRYFFYSSG 120
+G G ++Y+ + + VAI + + KR + +++ + H N+V+ ++ +S
Sbjct: 1091 LGKGEHSIIYKGRRKGTINFVAIHCIEKCKRPEVTNTVRMTHDISHPNVVQFHEWYETSN 912
Query: 121 EKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHR 180
+L LV++ T +A ++ LP ++ + L L YIHS GI
Sbjct: 911 ------HLWLVVELC--TGGSLADILAQDHH-LPETSIRDFGIHLVTGLHYIHSLGILFH 759
Query: 181 DIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRY------------------- 221
D++P +LLD + VLK DFG +K V GE N+ + ++
Sbjct: 758 DLRPSKVLLDT-SGVLKFADFGLSK--VEGE-NLEELFFKFAEAGDQWNIQSAEEMMKQV 591
Query: 222 -------YRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLG 274
Y APE+ GA S D+W+ GCV E+ G P F G++ +I
Sbjct: 590 PTSGSPTYMAPEVFQGAEPSIMS-DLWALGCVFYEMFSGHPPFLGET-----YDI----- 444
Query: 275 TPTREQIREMNPNYTEFKFPQIKAHPWTKVFRPRTPPEAIALCSRLLEYTPTARLTPLEA 334
T++++ EF P++K + PE + L LL+ T RL+
Sbjct: 443 --TKDKVLN-----KEFPLPKVKG----SRLSAKPSPEFLNLLESLLQKDSTRRLSWASL 297
Query: 335 CAHSFF 340
H+F+
Sbjct: 296 VKHAFW 279
>15910
Length = 1361
Score = 70.9 bits (172), Expect = 9e-13, Method: Compositional matrix adjust.
Identities = 54/173 (31%), Positives = 84/173 (48%), Gaps = 3/173 (1%)
Frame = +2
Query: 165 LFRSLAYIHSFGICHRDIKPQNLLLD--PDTAVLKLCDFGSAKQLVRGEPNVSYICSR-Y 221
+ + YIH+ G+ HRD+KP+NLL + D + LKL DFG ++ ++ E +S +C
Sbjct: 491 ILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLADFGLSR-IIEPEVQMSTVCGTPG 667
Query: 222 YRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQI 281
Y APE++ G YT S+D+WS G + LL G F ++ + +IIK
Sbjct: 668 YCAPEVLKG-DKYTPSVDMWSVGVIAYILLCGYEPFFAENEFEMYRKIIK---------- 814
Query: 282 REMNPNYTEFKFPQIKAHPWTKVFRPRTPPEAIALCSRLLEYTPTARLTPLEA 334
E+KF + W+++ A + +LL P RLT EA
Sbjct: 815 -------GEYKFDE---EYWSEI-----SENAKDVVRKLLVIDPKKRLTATEA 928
>13066
Length = 551
Score = 70.5 bits (171), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 59/199 (29%), Positives = 96/199 (48%), Gaps = 15/199 (7%)
Frame = +3
Query: 61 VIGNGSFGVVYQAKLCDSGELVAIKKVLQD--KRFKNRELQIMRKLDHCNIVRLR----- 113
V+ +G+F Y + + +++ +K D ++F REL ++ KLDH I+++
Sbjct: 12 VVVHGTFNDGYGRNIKLACKIIDKEKAPVDFVEKFFPRELDLLTKLDHPYIIQIHSILQR 191
Query: 114 ----YFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSL 169
+ F E+ D +L Y+ E + + KQ K++ YQ+ +L
Sbjct: 192 XPKNFIFMRFAERGD------LLTYIQEV------GFVKEKQA------KIWFYQMTTAL 317
Query: 170 AYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLV--RGEPNVS--YICSRYYRAP 225
Y+HS+ + HRD+K +N+LL V KL DFG A + GE +S Y S Y AP
Sbjct: 318 NYLHSYDVAHRDLKCENILLSSHFNV-KLADFGFACACITESGEKYMSRTYCGSAAYAAP 494
Query: 226 ELIFGATDYTSSIDVWSAG 244
E+++GA D WS G
Sbjct: 495 EIVYGAPYAPKVADAWSLG 551
>12453
Length = 680
Score = 68.2 bits (165), Expect = 6e-12, Method: Compositional matrix adjust.
Identities = 39/144 (27%), Positives = 69/144 (47%), Gaps = 2/144 (1%)
Frame = +3
Query: 244 GCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREM--NPNYTEFKFPQIKAHPW 301
GC+ E+ G+P+FPG + D+L I K LGTPT + + + NP++ P +
Sbjct: 9 GCIFYEMACGRPLFPGSTVEDELHLIFKTLGTPTEDSLPSISRNPDFLALNLPHYQGEAL 188
Query: 302 TKVFRPRTPPEAIALCSRLLEYTPTARLTPLEACAHSFFDELRDPNVKLPNGRDTPALFN 361
+ PR + + L ++ L+Y R++ ++ HSFF+ L LP DT + F
Sbjct: 189 ITI-APRLDSDGLDLLAKFLKYNAKIRVSAADSLKHSFFNSLGPGVHMLP---DTVSAFT 356
Query: 362 FTTQELSSNPPLATILIPPHARIQ 385
L +P + + + +I+
Sbjct: 357 VPGISLHRDPGIRSSSVASTGKIR 428
>18484
Length = 635
Score = 68.2 bits (165), Expect = 6e-12, Method: Compositional matrix adjust.
Identities = 57/195 (29%), Positives = 87/195 (44%), Gaps = 2/195 (1%)
Frame = +1
Query: 137 ETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVL 196
+ +YR+ + K PV Y ++ L ++H GI +RD+K N++LD + +
Sbjct: 1 DLMYRIQQ---EGKFKEPV--AAFYAAEIAVGLFFLHDQGIIYRDLKLDNVMLDSEGHI- 162
Query: 197 KLCDFGSAKQLVRGEPNVSYICSR-YYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQP 255
K+ DFG K+ + G+ C Y APE++ Y+ S+D W+ G +L E+L GQP
Sbjct: 163 KIADFGMCKEGMTGDATTRTFCGTPDYIAPEIVL-YQPYSKSVDWWAYGVLLFEMLAGQP 339
Query: 256 IFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHPWTKVFRPRTPP-EAI 314
F G+ D+L F I H V P+ EA+
Sbjct: 340 PFDGED-EDEL--------------------------FSSITDH---NVSYPKAMSREAV 429
Query: 315 ALCSRLLEYTPTARL 329
+LC LL PT RL
Sbjct: 430 SLCKGLLMKNPTKRL 474
>06405
Length = 1965
Score = 68.2 bits (165), Expect = 7e-12, Method: Compositional matrix adjust.
Identities = 64/238 (26%), Positives = 118/238 (49%), Gaps = 12/238 (5%)
Frame = +1
Query: 48 PDRPQEVSYTDTKV---IGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKN---RELQIM 101
PDR E+ T+ + +G G +G VY+A ++VA+K + +D N E IM
Sbjct: 235 PDR-WEIERTEIAMKHRLGGGQYGDVYEAMWKRYNKIVAVKTLKEDTMALNDFLEEAAIM 411
Query: 102 RKLDHCNIVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLY 161
+++ H N+V+L G E +V +++P S ++ P +Y
Sbjct: 412 KEMKHPNLVQLL------GVCTREPPFYIVTEFMPHGNLLDYLRSSTREENGPTAL--MY 567
Query: 162 MY-QLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSR 220
M Q+ +AY+ + HRD+ +N L+ D+ ++K+ DFG A+ L++ + ++I ++
Sbjct: 568 MATQIASGMAYLETKNFIHRDLAARNCLVA-DSNMVKVADFGLAR-LMKDDTYTAHIGAK 741
Query: 221 Y---YRAPE-LIFGATDYTSSIDVWSAGCVLAEL-LLGQPIFPGDSGVDQLVEIIKVL 273
+ + APE L F +++ D+W+ G +L EL G +PG +L E+ +L
Sbjct: 742 FPIKWTAPEGLAFNR--FSTRSDIWAFGVLLWELATYGMSPYPG----VELTEVYHLL 897
>30755
Length = 1137
Score = 67.0 bits (162), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 37/108 (34%), Positives = 60/108 (55%), Gaps = 2/108 (1%)
Frame = +2
Query: 158 VKLYMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQ-LVRGEPNVSY 216
+ Y ++ +L Y+HS GI +RD+K +NLLLD D + K+ DFG K+ + G ++
Sbjct: 38 TRFYGAEIISALGYLHSQGIIYRDLKLENLLLDKDGHI-KVADFGLCKEDITYGRTTKTF 214
Query: 217 ICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQ-PIFPGDSGV 263
+ Y APE + DY ++D W G V+ E++ G+ P + D V
Sbjct: 215 CGTPEYLAPE-VLDDNDYGRAVDWWGTGVVMYEMICGRLPFYNRDHDV 355
>19301
Length = 712
Score = 65.9 bits (159), Expect = 3e-11, Method: Compositional matrix adjust.
Identities = 46/150 (30%), Positives = 78/150 (52%)
Frame = +2
Query: 55 SYTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRY 114
S TD + +G+G+ G V+ KLC E VA+KKV + K +++ +RKL+H NI+ +
Sbjct: 308 SITDLEWLGSGAQGAVFLGKLC--AEEVAVKKV---RDIKETDIRNLRKLNHPNIISFK- 469
Query: 115 FFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHS 174
G ++++Y P Y R + +P V + Q+ + Y+HS
Sbjct: 470 -----GVCTQAPCYCIIMEYCP---YGQLYEVLRDGKEIPPALVLDWSKQIASGMNYLHS 625
Query: 175 FGICHRDIKPQNLLLDPDTAVLKLCDFGSA 204
I HRD+K N+L+ + V+K+ DFG++
Sbjct: 626 HKIIHRDLKSPNVLVAKND-VVKISDFGTS 712
>01966
Length = 1735
Score = 65.1 bits (157), Expect = 5e-11, Method: Compositional matrix adjust.
Identities = 40/127 (31%), Positives = 66/127 (51%), Gaps = 4/127 (3%)
Frame = -3
Query: 218 CSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPT 277
C P GA+ Y++ +DVWS G + A++L+ PIF GDS +DQL +I +++GTPT
Sbjct: 1223 CDLVVPGPRDPHGASKYSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPT 1044
Query: 278 REQIREMN--PNYTEFKFPQIKAHPWTKVFRPRTPPEAIA--LCSRLLEYTPTARLTPLE 333
+ E + P + FP K K+ T +++ L R L+ P R++ +
Sbjct: 1043 EQTWPEFHKLPAFNGM-FPLWKE---GKLSETLTDLDSLGLDLIERTLKCDPAQRISCKK 876
Query: 334 ACAHSFF 340
H++F
Sbjct: 875 MLQHAYF 855
Score = 64.7 bits (156), Expect = 6e-11, Method: Compositional matrix adjust.
Identities = 50/162 (30%), Positives = 76/162 (46%), Gaps = 11/162 (6%)
Frame = -1
Query: 96 RELQIMRKLDHCNIVRL--------RYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYS 147
RE+ ++R+L H NIV L R F D L + +D PE V R
Sbjct: 1567 REIAMLRELRHTNIVCLEDVIMEDERLFLVFEFLSMD---LKMYIDKFPEGVVLDRR--- 1406
Query: 148 RAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQL 207
VK Y++Q+ + + H I HRD+KPQNLL++ T +K+ DFG A+
Sbjct: 1405 ---------LVKSYVFQIVTGINFCHQRRIVHRDLKPQNLLIN-HTGAIKIADFGMARTF 1256
Query: 208 VRGEPNVSY---ICSRYYRAPELIFGATDYTSSIDVWSAGCV 246
P +Y + + +YRAPE++ G S+ W+ G +
Sbjct: 1255 --ALPVRAYTHEVVTLWYRAPEILMGP---QSTPPXWTCGAL 1145
>09007
Length = 1440
Score = 64.3 bits (155), Expect = 9e-11, Method: Compositional matrix adjust.
Identities = 63/232 (27%), Positives = 108/232 (46%), Gaps = 15/232 (6%)
Frame = -1
Query: 35 SKVTTVVATPGQGPDRPQEVSYTDTKVIGNGSFGVVYQAKL-CDSGE--LVAIKKVLQDK 91
S+ + V P +G + +K +G G FG V QA +SGE VA+K + +DK
Sbjct: 936 SRPVSAVVRPARGKQLISKDCVALSKSLGQGHFGTVRQAIWTAESGEKVQVAVKCLSKDK 757
Query: 92 RFKN-----RELQIMRKLDHCNIVRLRYFFYSSGEKKDEVYLNLVLDYVP-ETVYRVARH 145
K+ +E IM+ LDH NIVR+ +G + LV + P ++ +
Sbjct: 756 IHKDGQEFLKETAIMQMLDHENIVRVYGVVMDNGAD-----IMLVTELAPMRSLLECVKE 592
Query: 146 YSRAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCD----- 200
S A+ V + + Q+ ++Y+ S + HRD+ +N+LL + V K+ D
Sbjct: 591 VS-ARVDFSVPRLCDFSQQVCDGMSYLESKRLVHRDLAARNILLFSKSKV-KISDVGVSG 418
Query: 201 -FGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELL 251
G+ K+ + + + + + APE F ++S+ DVW+ G +L E
Sbjct: 417 ALGAGKEYYQSQQTIHLQNAVAWCAPE-SFRNLCFSSASDVWAFGVLLWEFF 265
>26560
Length = 398
Score = 63.9 bits (154), Expect = 1e-10, Method: Composition-based stats.
Identities = 37/113 (32%), Positives = 62/113 (54%), Gaps = 4/113 (3%)
Frame = -1
Query: 158 VKLYMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYI 217
V+ Y ++ L ++HS + +RD+KP N+LLD + V ++ D G A + P+ S +
Sbjct: 350 VRFYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHV-RISDLGLACDFSKKRPHAS-V 177
Query: 218 CSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIF----PGDSGVDQL 266
+ Y APE++ Y SS D +S GC+L +LL G F G + +D++
Sbjct: 176 GTHGYMAPEVLMKGQSYDSSADWFSFGCMLYKLLKGHSPFRQHNQGQARIDRM 18
>14116
Length = 1017
Score = 62.4 bits (150), Expect = 3e-10, Method: Compositional matrix adjust.
Identities = 61/211 (28%), Positives = 90/211 (42%), Gaps = 21/211 (9%)
Frame = -1
Query: 62 IGNGSFGVVYQAKLC---DSGELVAIKKVLQDKRFKNRELQ-------IMRKLDHCNIVR 111
IG G+FG V + L G+++ K L + + ELQ IM+ H N++
Sbjct: 612 IGKGNFGCVKRGFLTLPEQKGDILVAVKTLHNNNPREIELQSFLQEALIMKDFHHSNVLT 433
Query: 112 LRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARH-----YSRAKQTLPVIY-VKLYMYQL 165
L + + L LD +P V +H Y R Q P I + +Y +
Sbjct: 432 L-------------IGICLNLDDMPLVVLPFMKHGDLLTYIRDDQHQPTIKDLIMYGVDI 292
Query: 166 FRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSA-----KQLVRGEPNVSYICSR 220
R + Y+ HRD+ +N +LD D V K+ DFG A K+ E + + +
Sbjct: 291 ARGMDYLAGLKFVHRDLAARNCMLDEDFHV-KVADFGLARDIYEKEYYSSENKKAKLPVK 115
Query: 221 YYRAPELIFGATDYTSSIDVWSAGCVLAELL 251
+ L G +Y S DVWS G VL ELL
Sbjct: 114 WMALESLEKG--NYDSKTDVWSYGVVLWELL 28
>31885
Length = 529
Score = 62.0 bits (149), Expect = 4e-10, Method: Compositional matrix adjust.
Identities = 54/158 (34%), Positives = 77/158 (48%), Gaps = 4/158 (2%)
Frame = -2
Query: 98 LQIMRKLDHCNIVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIY 157
+ ++ +LDH +V L Y F +DE L +V+D + R++ + + +
Sbjct: 519 VDMLTRLDHPFLVNLWYAF------QDEEDLFMVVDLF---LGGDLRYHMQQEVSFREDC 367
Query: 158 VKLYMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYI 217
VK Y+ QL L Y+ S I HRDIKP N+LLD + + DF A QL E S
Sbjct: 366 VKFYLCQLALVLDYLRSQKIVHRDIKPDNILLD-EQGHCHVTDFNIATQLEDDELATSTS 190
Query: 218 CSRYYRAPELIFGATD----YTSSIDVWSAGCVLAELL 251
+R Y APE+ A + Y +D WS G L ELL
Sbjct: 189 GTRPYMAPEVYGVAINERRGYGFPVDWWSLGVSLFELL 76
>12786
Length = 460
Score = 61.6 bits (148), Expect = 6e-10, Method: Compositional matrix adjust.
Identities = 41/135 (30%), Positives = 65/135 (48%), Gaps = 24/135 (17%)
Frame = -3
Query: 147 SRAKQT--LPVIYVKLYMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSA 204
+RAKQ L + +K Y ++ R++ +H+ G+ H D+KP N +L LKL DFG A
Sbjct: 443 ARAKQEQGLDRMMIKFYWREMLRAVKALHNEGVIHSDLKPANFMLVAGN--LKLIDFGIA 270
Query: 205 KQLVRGEPNV---SYICSRYYRAPELIFGATDYTSS-------------------IDVWS 242
L + + +V S + + Y +PE I A D ++ DVWS
Sbjct: 269 NTLQQDKTSVLKDSRVGTPSYMSPEAIMAACDDSADDSMEEDGHRTKPKYKVGVRSDVWS 90
Query: 243 AGCVLAELLLGQPIF 257
GC+L ++ G+ F
Sbjct: 89 LGCILYNMVYGRTPF 45
>01718
Length = 959
Score = 60.8 bits (146), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 52/204 (25%), Positives = 92/204 (45%), Gaps = 7/204 (3%)
Frame = +3
Query: 62 IGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKN--RELQIMRKLDHCNIVRLRYFFYSS 119
IG G F V++ +G+++A+K N RE+Q++ +L H NI+R
Sbjct: 171 IGAGFFSEVFKVTHRITGQVMALKMNTMTSNRHNMLREVQLLNRLQHANILRFMGVCVHE 350
Query: 120 GEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFGICH 179
G+ L+ + +Y+P + + + + LP L R L Y+HS H
Sbjct: 351 GQ------LHALTEYIPSG--NLEQLLEKKDEELPWTQRIQLTLGLARGLDYLHSTRFIH 506
Query: 180 RDIKPQNLLL---DPDTAVLKLCDFGSAKQLVR--GEPNVSYICSRYYRAPELIFGATDY 234
RD+ +N+L+ D + DFG A ++ + + + S Y+ APE++ G Y
Sbjct: 507 RDLTSKNILIRREDNHGYHAVIADFGLATKIPDPLDKEKLPTVGSPYWMAPEVLNGHF-Y 683
Query: 235 TSSIDVWSAGCVLAELLLGQPIFP 258
D++S G ++ E+ P P
Sbjct: 684 NERADLFSVGIIMCEITARIPADP 755
>18287
Length = 678
Score = 60.5 bits (145), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 40/122 (32%), Positives = 55/122 (45%), Gaps = 11/122 (9%)
Frame = -3
Query: 234 YTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKF 293
Y SID+WS GC+ AELL + +F V QL II ++GTP P E
Sbjct: 673 YDYSIDIWSVGCIFAELLSRRILFQAQGPVQQLDMIINLVGTP--------RPEDMERAC 518
Query: 294 PQIKAHPWTKVFR-----------PRTPPEAIALCSRLLEYTPTARLTPLEACAHSFFDE 342
+ H + FR P EA+ L +R+L P R++ EA +H + DE
Sbjct: 517 EGARNHILNQPFRRQNLLTLYNLSPHATHEAVRLLTRMLILNPKNRISAEEALSHPYLDE 338
Query: 343 LR 344
R
Sbjct: 337 GR 332
>01392
Length = 1806
Score = 60.1 bits (144), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 39/119 (32%), Positives = 61/119 (51%), Gaps = 12/119 (10%)
Frame = -1
Query: 158 VKLYMYQLFRSLAYIHSFGICHRDIKPQNLLLD--PDTAVLKLCDFGSAKQL-VRGEPN- 213
L + + R+L ++HS GI HRD+KP+N+L + D +K+CDF A + G+
Sbjct: 1785 ASLVVRHIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGISCDGDGTK 1606
Query: 214 ----VSYICSRYYRAPELIFG----ATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVD 264
++ + S Y APE++ + Y D+WS G +L +L G P F G G D
Sbjct: 1605 TPELLTPVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILYIMLCGYPPFYGQCGED 1429
>13212
Length = 1067
Score = 59.3 bits (142), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 55/183 (30%), Positives = 80/183 (43%), Gaps = 5/183 (2%)
Frame = -1
Query: 163 YQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFG-SAKQLVRGEPNVSYICSRY 221
+++ +L ++H + HRDIK N+LL D V KL DFG SAK + ++I + Y
Sbjct: 959 HEMCMALDFLHRHHVIHRDIKAGNVLLTIDGEV-KLADFGVSAKNTQTQQKRDTFIGTPY 783
Query: 222 YRAPELI----FGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPT 277
+ APE++ T Y D+WS G L E I P + + + +IK
Sbjct: 782 WMAPEVVLCETLKDTPYDFKADIWSLGVTLIEFAQ---IEPPNKEMHPMRVLIK------ 630
Query: 278 REQIREMNPNYTEFKFPQIKAHPWTKVFRPRTPPEAIALCSRLLEYTPTARLTPLEACAH 337
I + +P E K WTK+F+ + IA C L P R T E H
Sbjct: 629 ---IHKSDPPTLE------KPKKWTKLFK-----DFIAKC---LVKDPNLRPTAAELLEH 501
Query: 338 SFF 340
F
Sbjct: 500 PFM 492
>14420
Length = 528
Score = 58.5 bits (140), Expect = 5e-09, Method: Compositional matrix adjust.
Identities = 32/93 (34%), Positives = 53/93 (56%), Gaps = 1/93 (1%)
Frame = +2
Query: 164 QLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVS-YICSRYY 222
+ ++L ++H + HRDIK N+LL D +V KL DFG QL + S + + Y+
Sbjct: 221 ECLQALEFLHENQVIHRDIKSDNILLGMDGSV-KLTDFGFCAQLSPEQSKRSTMVGTPYW 397
Query: 223 RAPELIFGATDYTSSIDVWSAGCVLAELLLGQP 255
APE++ Y ++D+WS G + E++ G+P
Sbjct: 398 MAPEVV-TRKQYGPTVDIWSLGVMCIEMIEGEP 493
>03294
Length = 1684
Score = 57.4 bits (137), Expect = 9e-09, Method: Compositional matrix adjust.
Identities = 35/107 (32%), Positives = 58/107 (54%), Gaps = 4/107 (3%)
Frame = -1
Query: 238 IDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMN--PNYTEFKFPQ 295
+DVWS G + A++L+ PIF GDS +DQL +I +++GTPT + E + P + FP
Sbjct: 1672 VDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKLPAFNGM-FPL 1496
Query: 296 IKAHPWTKVFRPRTPPEAIA--LCSRLLEYTPTARLTPLEACAHSFF 340
K K+ T +++ L R L+ P R++ + H++F
Sbjct: 1495 WKE---GKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYF 1364
>31489
Length = 329
Score = 57.0 bits (136), Expect = 1e-08, Method: Composition-based stats.
Identities = 29/91 (31%), Positives = 50/91 (54%)
Frame = +3
Query: 98 LQIMRKLDHCNIVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIY 157
++I++ H NI+ +R D +++V D + ++R+ YS Q L +
Sbjct: 3 IKILKHFKHDNIISIREILKPKDSYHDFKDIHVVFDLMESDLHRII--YS--DQPLTEEH 170
Query: 158 VKLYMYQLFRSLAYIHSFGICHRDIKPQNLL 188
++ ++YQ+ R L YIHS + HRD+KP NLL
Sbjct: 171 IRYFLYQILRGLKYIHSANVVHRDLKPSNLL 263
>27546
Length = 426
Score = 55.8 bits (133), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 39/126 (30%), Positives = 62/126 (49%), Gaps = 11/126 (8%)
Frame = -1
Query: 91 KRFKNRELQIMRKLDHCNIVRLR---------YFFYSSGEKKDEVYLNLVLDYVPETVYR 141
K+F REL+I+ +LDH NI+++ + F EK D +
Sbjct: 348 KKFFPRELEILTRLDHPNIIQIHSILQRGPKIFIFMRYAEKGDML--------------- 214
Query: 142 VARHYSRAKQTLPV--IYVKLYMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLC 199
S K+T P+ K++ +Q+ ++L Y+HS I HRD+K +N+LL V K+
Sbjct: 213 -----SHIKKTGPIDEAQTKVWFFQMAKALQYLHSHDIAHRDLKCENILLSKRLNV-KIA 52
Query: 200 DFGSAK 205
DFG A+
Sbjct: 51 DFGFAR 34
>17975
Length = 449
Score = 54.7 bits (130), Expect = 7e-08, Method: Compositional matrix adjust.
Identities = 42/152 (27%), Positives = 76/152 (50%), Gaps = 6/152 (3%)
Frame = +3
Query: 67 FGVVYQAKLCDSGELVAIKKVLQDK------RFKNRELQIMRKLDHCNIVRLRYFFYSSG 120
F VV A+ +GE VA+K + + K +E++ M+ + H N+VRL Y
Sbjct: 6 FAVVKLARHVFTGEKVAVKVIDKTKLDEVSRSHLFQEVRCMKLVQHPNVVRL----YEVI 173
Query: 121 EKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHR 180
+ + ++YL L L + + RH ++ L K Y Q+ +++Y H + HR
Sbjct: 174 DTQTKLYLILELGDGGDMYDYIMRHSGGLEEKLA----KRYFRQIVEAISYCHKLHVVHR 341
Query: 181 DIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEP 212
D+KP+N++ ++KL DFG + L++ +
Sbjct: 342 DLKPENVVFFEKPGLVKLTDFGFSTCLLQAKA 437
>27405
Length = 532
Score = 53.5 bits (127), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 54/190 (28%), Positives = 90/190 (47%), Gaps = 14/190 (7%)
Frame = -3
Query: 66 SFGVVYQAKLCDSGELVAIKKVLQDKRFKNR-------ELQIMRKLDHCN-----IVRLR 113
FG VY + D+G++ A+K L KR K + +IM L IV +
Sbjct: 530 GFGEVYGCRKADTGKMYAMK-CLDKKRIKMKGGETLALNERIMLSLVSTGEGSPFIVCMT 354
Query: 114 YFFYSSGEKKDEVYLNLVLDYV--PETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAY 171
Y F + EK L +LD + + Y +++H ++ V+ Y ++ L +
Sbjct: 353 YAFQTP-EK-----LCFILDLMNGGDLHYHLSQHGVFTEKE-----VRFYAAEVMLGLEH 207
Query: 172 IHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGA 231
+HS + +RD+KP N+LLD + V ++ D G A + +P+ S + + Y APE++
Sbjct: 206 MHSRFVVYRDLKPANILLDENGHV-RISDLGLACDFSKKKPHAS-VGTHGYMAPEVLMKG 33
Query: 232 TDYTSSIDVW 241
Y SS D W
Sbjct: 32 QAYDSSAD-W 6
>18401
Length = 463
Score = 53.5 bits (127), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 35/140 (25%), Positives = 61/140 (43%), Gaps = 16/140 (11%)
Frame = -3
Query: 217 ICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGT- 275
+ +R+YRAPE+I ++ DVWS GC++ EL G +F + L + ++LG+
Sbjct: 449 VSTRHYRAPEVIL-ELGWSHPCDVWSVGCIMFELYTGYTLFQTHDNKEHLAMMERILGSL 273
Query: 276 PTREQIREMNPNYTEF------------KFPQIKAHPWTKVFRPRTPPEA---IALCSRL 320
P R + Y ++ + P + + R + L +L
Sbjct: 272 PYRMAKKTKKQKYFHHGRLDVPERSSMARYVRENTKPLLRYVKDRENKDHQQLFDLMKKL 93
Query: 321 LEYTPTARLTPLEACAHSFF 340
L Y ++R + L+A H FF
Sbjct: 92 LAYEASSRYSLLQALQHPFF 33
>26711
Length = 405
Score = 52.4 bits (124), Expect = 4e-07, Method: Composition-based stats.
Identities = 33/104 (31%), Positives = 53/104 (50%), Gaps = 1/104 (0%)
Frame = -2
Query: 164 QLFRSLAYIHSFGICHRDIKPQNLLLDPDTA-VLKLCDFGSAKQLVRGEPNVSYICSRYY 222
Q+ L ++H+ G+ H D+KP NLLL D ++L DFG A++L + + +
Sbjct: 392 QVLDILQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARKLYPPQETFLNHGTPGF 213
Query: 223 RAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQL 266
+PE + +++ DVW G + LL GQ F DS + L
Sbjct: 212 TSPEAL-DVKPISTASDVWGVGVLAYILLSGQSPFQADSATESL 84
>07940
Length = 1336
Score = 52.4 bits (124), Expect = 4e-07, Method: Compositional matrix adjust.
Identities = 36/102 (35%), Positives = 53/102 (51%), Gaps = 4/102 (3%)
Frame = -3
Query: 161 YMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSR 220
Y YQ+ R + Y+ S HRD+ +N+L+ + VLK+ DFG + L + + R
Sbjct: 332 YAYQVARGMEYLASKQCIHRDLAARNVLV-AEEYVLKIADFGLTRNLQQFDYYRKTTDGR 156
Query: 221 Y---YRAPELIFGATDYTSSIDVWSAGCVLAELL-LGQPIFP 258
+ APE +F YTS DVWS G +L E+ LG +P
Sbjct: 155 LPVKWMAPEALFD-RKYTSKSDVWSYGVLLWEIFTLGGNPYP 33
>11185
Length = 473
Score = 51.6 bits (122), Expect = 7e-07, Method: Compositional matrix adjust.
Identities = 38/122 (31%), Positives = 54/122 (44%), Gaps = 26/122 (21%)
Frame = +1
Query: 158 VKLYMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYI 217
++ + L L YIHS GI D++P +LLD + VLK DFG +K V GE N+ +
Sbjct: 7 IRDFGIHLVTGLHYIHSLGILFHDLRPSKVLLDT-SGVLKFADFGLSK--VEGE-NLEEL 174
Query: 218 CSRY--------------------------YRAPELIFGATDYTSSIDVWSAGCVLAELL 251
++ Y APE+ GA S D+W+ GCV E+
Sbjct: 175 FFKFAEAGDQWNIQSAEEMMKQVPTSGSPTYMAPEVFQGAEPSIMS-DLWALGCVFYEMF 351
Query: 252 LG 253
G
Sbjct: 352 SG 357
>19761
Length = 473
Score = 51.2 bits (121), Expect = 7e-07, Method: Compositional matrix adjust.
Identities = 38/128 (29%), Positives = 63/128 (49%), Gaps = 6/128 (4%)
Frame = -3
Query: 153 LPVIYVKLYMYQLFRSLAYIHSFG--ICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVR- 209
LP + ++ Q +L Y+H+ I HRD+KPQN+ + V +L D G A++L
Sbjct: 432 LPERLIVCWLMQTASALNYMHTHTPVILHRDLKPQNIYVTEKGDV-RLGDLGLARKLTGP 256
Query: 210 GEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQ---L 266
+ S + + Y +PE I Y S D+WS GCV ++ G G D+ +
Sbjct: 255 ADFATSQVGTIMYLSPE-ILSQQPYNSKSDIWSLGCVFYDI-------TGKKGSDEMGVM 100
Query: 267 VEIIKVLG 274
+++V+G
Sbjct: 99 FLLVQVMG 76
>19094
Length = 898
Score = 51.2 bits (121), Expect = 8e-07, Method: Compositional matrix adjust.
Identities = 35/95 (36%), Positives = 48/95 (50%), Gaps = 2/95 (2%)
Frame = +1
Query: 162 MYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQL--VRGEPNVSYICS 219
+Y + L Y+HS HRDIK N+LL+ + KL DFG A QL + N + I +
Sbjct: 76 LYYTLKGL*YLHSRRKIHRDIKAGNILLNNEGHA-KLADFGVAGQLTDTMAKRN-TVIGT 249
Query: 220 RYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQ 254
Y+ APE+I Y D+WS G E+ G
Sbjct: 250 PYWMAPEVIQ-EIGYDCVADIWSLGITALEMAEGN 351
>21433
Length = 590
Score = 49.7 bits (117), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 36/96 (37%), Positives = 51/96 (53%), Gaps = 1/96 (1%)
Frame = +2
Query: 161 YMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSR 220
Y+YQL +L Y H + HRDIKP+NLLL LK+ DFG + +C
Sbjct: 182 YIYQLSSALEYCHYRKVIHRDIKPENLLLG-LKGDLKIADFGWSVHAPSSRRTT--MCGT 352
Query: 221 Y-YRAPELIFGATDYTSSIDVWSAGCVLAELLLGQP 255
Y PE++ G T + ++D+WS G + E L+G P
Sbjct: 353 LDYLPPEMVEGKT-HDENVDLWSLGVLCYEFLVGTP 457
>14477
Length = 493
Score = 49.3 bits (116), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 52/179 (29%), Positives = 84/179 (46%), Gaps = 9/179 (5%)
Frame = -1
Query: 57 TDTKVIGNGSFGVVYQAKLC--DSGELVAIKKVLQDKRFK-------NRELQIMRKLDHC 107
D +G G+FG V + +C D E+ KVL++ +E ++M+K+DH
Sbjct: 481 MDELKLGAGNFGSVMKG-VCRLDDREIPVAIKVLKNADLDPSVQSELIKEAEVMKKMDHM 305
Query: 108 NIVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFR 167
+IVRL GE + LVL+ + + + + K LP+ + M+Q+ +
Sbjct: 304 HIVRL--IGLCEGET-----MMLVLELAK--LGPLNKFLPKNKH-LPLWNILELMWQVSQ 155
Query: 168 SLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPE 226
+ Y+ + HRD+ +N+LL D K+ DFG +K L R E N YY A E
Sbjct: 154 GMEYLEANKFVHRDLAARNILL-CDEHFAKISDFGMSKTLSR-ENN-------YYMAQE 5
>00715
Length = 1788
Score = 48.5 bits (114), Expect = 5e-06, Method: Compositional matrix adjust.
Identities = 38/119 (31%), Positives = 50/119 (42%), Gaps = 23/119 (19%)
Frame = +1
Query: 164 QLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQL---------------- 207
Q+ R L Y+HS I H D+KP N LL D L++ DFG QL
Sbjct: 262 QMARGLHYLHSINIVHLDLKPANCLLTRDLK-LRIADFGCCHQLTPTGLDMGEREGGMAG 438
Query: 208 -------VRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPG 259
V+G + YRAPEL+ G S DV+S G L ++ Q + G
Sbjct: 439 NELELTPVQGAWKNELAGTLAYRAPELLKGLQPSVRS-DVYSLGITLWQMCTRQGPYEG 612
>04852
Length = 1462
Score = 47.0 bits (110), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 32/97 (32%), Positives = 50/97 (51%), Gaps = 2/97 (2%)
Frame = +1
Query: 161 YMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSR 220
Y +Q+ R + ++ S HRD+ +N+L+ + VLK+ DFG ++ +
Sbjct: 340 YAFQIARGMEFLASRKCIHRDLAARNVLV-TEEHVLKIADFGLSRTGDYYKKRSGGRLPV 516
Query: 221 YYRAPELIFGATDYTSSIDVWSAGCVLAEL--LLGQP 255
+ APE +F YT+ DVWS G VL E+ L G P
Sbjct: 517 KWMAPEALFDMR-YTTKSDVWSFGVVLWEIFSLGGMP 624
>28157
Length = 400
Score = 46.6 bits (109), Expect = 2e-05, Method: Composition-based stats.
Identities = 38/128 (29%), Positives = 62/128 (48%), Gaps = 5/128 (3%)
Frame = +3
Query: 82 VAIKKVL--QDKRFKNRELQIMRKLDHCNIVRLRYFFYSSGEKKDEVYLNLVLDYVPETV 139
VA+K++ Q+K+ +EL+ + ++ H NIV L G +D + LV++Y
Sbjct: 9 VAVKRIESEQEKKSFMQELKQLSRVSHPNIVCL------YGACRDHP-VCLVMEYAEGGS 167
Query: 140 YRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSF---GICHRDIKPQNLLLDPDTAVL 196
H S + + ++ Q + Y+H + HRD+KP NLLL L
Sbjct: 168 LYNVLHGSGPQPQYTAAHAMNWLLQCALGVEYLHGMKPKALIHRDLKPPNLLLIQCGTKL 347
Query: 197 KLCDFGSA 204
K+CDFG+A
Sbjct: 348 KICDFGTA 371
>21808
Length = 1011
Score = 46.6 bits (109), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 44/177 (24%), Positives = 87/177 (49%), Gaps = 4/177 (2%)
Frame = +1
Query: 97 ELQIMRKLDHCNIVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVI 156
E QIM+KL H +++L Y+ + D +++ L ++ + R + +I
Sbjct: 82 EAQIMKKLRHPKLIQL----YAVCTQDDPIFIITEL-MKNGSLLEFLQGKGRVLKLPALI 246
Query: 157 YVKLYMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSY 216
+ Q+ +AY+ S HRD+ +N+L+ D +K+ DFG A+ +++ + +
Sbjct: 247 DIGA---QIACGMAYLESQNYIHRDLAARNILVS-DNNTVKIADFGLAR-VIKEDEYEAR 411
Query: 217 ICSRY---YRAPELIFGATDYTSSIDVWSAGCVLAE-LLLGQPIFPGDSGVDQLVEI 269
+ +R+ + APE +T DVWS G +L E + G+ +PG + + L ++
Sbjct: 412 VGARFPIKWTAPEAA-NYNRFTIKSDVWSFGILLTETVTYGRVPYPGMTNAEVLHQV 579
>11404
Length = 563
Score = 45.1 bits (105), Expect = 5e-05, Method: Compositional matrix adjust.
Identities = 49/162 (30%), Positives = 79/162 (48%), Gaps = 13/162 (8%)
Frame = +1
Query: 41 VATPGQG-PDRPQEVSYTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRE-- 97
+ +PG+ DR Y +IG GSFG V +A E VAIK + K F N+
Sbjct: 112 IISPGEKWADR-----YEIDSLIGKGSFGQVVKAYDHTDNEQVAIKIIKNKKPFLNQAQI 276
Query: 98 ----LQIMRKLDHCN---IVRL-RYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRA 149
L++M + D N IVRL R+F + S +L LV + + +Y + R+ +
Sbjct: 277 EVKLLEMMNRHDTDNKYYIVRLKRHFMFRS-------HLCLVFELLSYNLYDLLRNTNFR 435
Query: 150 KQTLPVIYVKLYMYQLFRSLAYIHS--FGICHRDIKPQNLLL 189
+L + + + QL +L ++ + I H D+KP+N+LL
Sbjct: 436 GVSLNL--TRKFAQQLCTALLFLATPEMSIIHCDLKPENILL 555
>21079
Length = 878
Score = 44.7 bits (104), Expect = 7e-05, Method: Compositional matrix adjust.
Identities = 28/95 (29%), Positives = 52/95 (54%), Gaps = 2/95 (2%)
Frame = +1
Query: 161 YMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTA-VLKLCDFGSAKQLVRGEPNVSYICS 219
++ Q+ + Y+H+ I H D+KP+N+L D + +K+ DFG A+ G+ +
Sbjct: 142 FVRQICSGVGYMHTQSILHLDLKPENVLCVSDNSNQIKIIDFGLARFYKPGDSLQVLFGT 321
Query: 220 RYYRAPELI-FGATDYTSSIDVWSAGCVLAELLLG 253
+ APE++ + ++T+ D+WS G + LL G
Sbjct: 322 PEFIAPEVVNYDEINFTT--DMWSIGVICYILLSG 420
>12672
Length = 773
Score = 44.3 bits (103), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 32/90 (35%), Positives = 46/90 (51%), Gaps = 5/90 (5%)
Frame = +3
Query: 169 LAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGE----PNVS-YICSRYYR 223
+ Y++ G HRDIK N+LLD + K+ DF + GE N S I + Y
Sbjct: 30 IQYLNDNGHVHRDIKTANILLDSEYTA-KVGDFATVVSAPSGEGKTVQNASVVIGTAAYL 206
Query: 224 APELIFGATDYTSSIDVWSAGCVLAELLLG 253
APE I D ++ +D +S G VL E++ G
Sbjct: 207 APEAIH--FDVSTKLDSYSFGVVLLEVITG 290
>16708
Length = 1397
Score = 42.4 bits (98), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 42/158 (26%), Positives = 69/158 (43%), Gaps = 12/158 (7%)
Frame = -1
Query: 60 KVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSS 119
+V+G G FG VY+A+L + E A+K + + L + L R+ FY +
Sbjct: 1385 QVLGKGVFGKVYEARLLSTHEKAALKTSI----LCHHSLDEVEALG-----RIEGGFYLA 1233
Query: 120 GEKKDEVY------LNLVLD-YVPETVYRVARHYSRAKQTLPVIYVKLYMY-----QLFR 167
V +N++L Y + V HY + +P+ + M Q
Sbjct: 1232 QMFGAWVTCLPFPKMNILLHFYEMGPLCNVYAHYK--NKEMPIRWSNPAMVCCIAGQXVC 1059
Query: 168 SLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAK 205
+L +IH G+ H D+K N+L+D KL D+G A+
Sbjct: 1058 ALEHIHELGVVHMDVKADNVLVDAH-GNCKLTDYGIAQ 948
>07291
Length = 833
Score = 40.4 bits (93), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 30/112 (26%), Positives = 51/112 (45%), Gaps = 7/112 (6%)
Frame = +1
Query: 147 SRAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQ 206
++ + L V+ + + Q+ +AY+ + HR++ +N ++ D L+L D+G
Sbjct: 22 AKPSKMLTVVQLLDFGRQIADGMAYLQEVKVVHRNLAARNCIVTED-GRLQLSDYGVTGS 198
Query: 207 LVRGEPNVSYICSRY-------YRAPELIFGATDYTSSIDVWSAGCVLAELL 251
L P Y + APE I ++S DVW+ G VL ELL
Sbjct: 199 LF---PQSYYTADDSPARDLVKWMAPETI-DNFHFSSKSDVWAFGVVLWELL 342
>00638
Length = 1595
Score = 40.0 bits (92), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 15/39 (38%), Positives = 25/39 (64%)
Frame = +2
Query: 146 YSRAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHRDIKP 184
+ + QT ++ Y+Y+L ++L + HS GI HRD+KP
Sbjct: 386 FKQLYQTFTDYDIRFYLYELMKALDFCHSMGIMHRDVKP 502
>36481
Length = 806
Score = 39.7 bits (91), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 34/138 (24%), Positives = 60/138 (43%), Gaps = 11/138 (7%)
Frame = +2
Query: 63 GNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNR---ELQIMRKL-------DHCNIVRL 112
G G+FG V Q K G+ +A+K + +++ E+ ++ KL H + L
Sbjct: 389 GEGTFGKVVQCKDLLKGDDIALKIIKNVDKYREAAKLEINVLEKLREKDPHAKHMCVQML 568
Query: 113 RYFFYSSGEKKDEVYLNL-VLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAY 171
+F Y L L V D++ + Y P+ V+ YQL ++ +
Sbjct: 569 DWFDYHGHVCISFHMLGLSVFDFLKDNSY----------GAYPIEQVRHISYQLCYAVNF 718
Query: 172 IHSFGICHRDIKPQNLLL 189
+H + H D+KP+N+L
Sbjct: 719 LHENQLTHTDLKPENILF 772
>16003
Length = 926
Score = 39.3 bits (90), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 21/58 (36%), Positives = 33/58 (56%), Gaps = 2/58 (3%)
Frame = -1
Query: 250 LLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMN--PNYTEFKFPQIKAHPWTKVF 305
LL+ P PGD+ +DQL +I +LGTPT + + P+Y +FK + P ++F
Sbjct: 926 LLIRLPFLPGDTDLDQLGKIFNMLGTPTETEWPAVTSLPDYIQFK--HCQKQPLKEIF 759
>26009
Length = 886
Score = 38.1 bits (87), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 18/36 (50%), Positives = 24/36 (66%), Gaps = 1/36 (2%)
Frame = +3
Query: 158 VKLYMYQLFRSLAYIHSFGICHRDIKPQN-LLLDPD 192
K M QL +L ++HS + HRDIKP+N L+L PD
Sbjct: 717 AKSVMKQLVSALDFMHSKQLVHRDIKPENVLILTPD 824
>25019
Length = 730
Score = 37.7 bits (86), Expect = 0.010, Method: Compositional matrix adjust.
Identities = 24/61 (39%), Positives = 31/61 (50%), Gaps = 1/61 (1%)
Frame = +3
Query: 185 QNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRY-YRAPELIFGATDYTSSIDVWSA 243
+N+LLD D V KL DFG K+ + G C Y APE I T + ++D WS
Sbjct: 261 ENVLLDKDGHV-KLTDFGLCKEAITGTRVTHTFCGTIEYMAPE-ILTRTGHGKAVDWWSL 434
Query: 244 G 244
G
Sbjct: 435 G 437
>21800
Length = 855
Score = 37.7 bits (86), Expect = 0.010, Method: Compositional matrix adjust.
Identities = 19/43 (44%), Positives = 27/43 (62%), Gaps = 1/43 (2%)
Frame = +2
Query: 151 QTLPVIYVKLYMYQLFRSLAYIHS-FGICHRDIKPQNLLLDPD 192
Q +PV VKL + Q+ L Y+H+ I H DIKP+N+L+ D
Sbjct: 617 QGIPVHNVKLIIRQVLEGLNYLHAKCNIIHTDIKPENILICVD 745
>01106
Length = 878
Score = 37.7 bits (86), Expect = 0.010, Method: Compositional matrix adjust.
Identities = 18/48 (37%), Positives = 30/48 (62%), Gaps = 1/48 (2%)
Frame = +3
Query: 151 QTLPVIYVKLYMYQLFRSLAYIHS-FGICHRDIKPQNLLLDPDTAVLK 197
Q +P+ VKL + Q+ L+Y+H+ I H DIKP+N+L+ D ++
Sbjct: 630 QGIPIHNVKLIIRQVLEGLSYMHAKCRIIHTDIKPENILICVDETYIR 773
>29360
Length = 363
Score = 35.8 bits (81), Expect = 0.030, Method: Composition-based stats.
Identities = 29/120 (24%), Positives = 57/120 (47%), Gaps = 8/120 (6%)
Frame = +3
Query: 78 SGELVAIKKVLQDKRFKNR---ELQIMRKL-----DHCNIVRLRYFFYSSGEKKDEVYLN 129
+ E+VAIK + + + E+ I+++L D N VR F + + +
Sbjct: 24 TSEIVAIKILKNHPSYARQGQIEVSILQRLSQESADDYNFVRAFECF------QHKNHTC 185
Query: 130 LVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHRDIKPQNLLL 189
LV + + + +Y + Q LP+ Y++ Q+ +L + G+ H D+KP+N++L
Sbjct: 186 LVFEMLEQNLYDFLKQ--NKFQPLPLKYIRPITQQVLTALRKLKQLGLIHADLKPENIML 359
>13078
Length = 773
Score = 35.4 bits (80), Expect = 0.039, Method: Compositional matrix adjust.
Identities = 13/42 (30%), Positives = 23/42 (54%)
Frame = -1
Query: 234 YTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGT 275
++ DVWS GC++ EL G +F + L + ++LG+
Sbjct: 746 WSQPCDVWSIGCIMFELYTGYTLFQTHDNKEHLAMMERILGS 621
>02638
Length = 1490
Score = 35.0 bits (79), Expect = 0.060, Method: Compositional matrix adjust.
Identities = 17/51 (33%), Positives = 28/51 (54%)
Frame = +1
Query: 222 YRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKV 272
+ APE++ G + Y + DVWS GCV+ E+ +P + + L I K+
Sbjct: 34 FMAPEVLRGES-YGRACDVWSVGCVMIEMCTCRPPWNSHDISNHLALIFKI 183
>00486
Length = 797
Score = 33.9 bits (76), Expect = 0.12, Method: Compositional matrix adjust.
Identities = 16/50 (32%), Positives = 28/50 (56%)
Frame = -2
Query: 222 YRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIK 271
Y APE I T + ++D WS G ++ ++L G P F ++ + +I+K
Sbjct: 760 YMAPE-ILTRTGHGKAVDWWSLGALMYDMLTGSPPFTAENRKKTIDKILK 614
>20152
Length = 445
Score = 33.5 bits (75), Expect = 0.15, Method: Compositional matrix adjust.
Identities = 22/86 (25%), Positives = 38/86 (44%), Gaps = 9/86 (10%)
Frame = +1
Query: 225 PELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKV-------LGTPT 277
PE++ G + ++DVWS G +L L++G+ F + + L I+ +
Sbjct: 1 PEILLGDSYDAPAVDVWSLGVILYMLVVGEAPFQEANDSETLTMIMDCRYQIPPHISHKC 180
Query: 278 REQIREM--NPNYTEFKFPQIKAHPW 301
++ I +M P I AHPW
Sbjct: 181 QDLIEKMLQREPVDRASLPHILAHPW 258
>37602
Length = 804
Score = 33.1 bits (74), Expect = 0.20, Method: Compositional matrix adjust.
Identities = 17/38 (44%), Positives = 22/38 (57%)
Frame = -1
Query: 164 QLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDF 201
+ + L Y+H G HRDIK N+LL + V KL DF
Sbjct: 195 ETLKGLHYLHRRGKMHRDIKGANILLTEEGDV-KLADF 85
>18481
Length = 437
Score = 32.0 bits (71), Expect = 0.44, Method: Compositional matrix adjust.
Identities = 18/45 (40%), Positives = 23/45 (51%), Gaps = 2/45 (4%)
Frame = -1
Query: 164 QLFRSLAYIHSFGICHRDIKPQNLL--LDPDTAVLKLCDFGSAKQ 206
QL L +IH HRD+KP N L L L + DFG +K+
Sbjct: 173 QLLSRLEFIHQKCFIHRDLKPDNFLMGLGRHCHRLYIIDFGLSKR 39
>35032
Length = 465
Score = 31.6 bits (70), Expect = 0.65, Method: Compositional matrix adjust.
Identities = 14/25 (56%), Positives = 15/25 (60%)
Frame = +3
Query: 316 LCSRLLEYTPTARLTPLEACAHSFF 340
L RLL Y P+ RLTP A AH F
Sbjct: 150 LVKRLLNYDPSKRLTPXXALAHPFL 224
>38560
Length = 479
Score = 30.8 bits (68), Expect = 1.0, Method: Compositional matrix adjust.
Identities = 16/32 (50%), Positives = 18/32 (56%)
Frame = -3
Query: 222 YRAPELIFGATDYTSSIDVWSAGCVLAELLLG 253
Y APELI G S D+WS G +L LL G
Sbjct: 387 YAAPELISGLEYLGSEADIWSMGVLLYALLCG 292
>19248
Length = 973
Score = 30.4 bits (67), Expect = 1.6, Method: Compositional matrix adjust.
Identities = 20/88 (22%), Positives = 41/88 (46%)
Frame = -3
Query: 6 RTTSFAESCKPVQQPSAFGSMKVSRDKDGSKVTTVVATPGQGPDRPQEVSYTDTKVIGNG 65
+T++ A PV+ P+ +GSM S+D G P+ P E S++D + G
Sbjct: 497 QTSAHAPQHYPVEDPAGYGSMHASKD-------------GNFPELPLESSHSDERGPCRG 357
Query: 66 SFGVVYQAKLCDSGELVAIKKVLQDKRF 93
S ++ + +L A+ ++ +++
Sbjct: 356 SHLLMMETHT**WRKLGAVSTIIWPRKY 273
>32357
Length = 625
Score = 30.0 bits (66), Expect = 1.6, Method: Compositional matrix adjust.
Identities = 16/37 (43%), Positives = 22/37 (59%)
Frame = -2
Query: 56 YTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKR 92
Y K IG+GSFG +Y SGE VA+K L++ +
Sbjct: 432 YRLMKKIGSGSFGEIYLGVHNTSGEEVAVKLELKNAK 322
>24241
Length = 413
Score = 30.0 bits (66), Expect = 1.8, Method: Composition-based stats.
Identities = 17/55 (30%), Positives = 30/55 (54%), Gaps = 10/55 (18%)
Frame = -2
Query: 62 IGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKN----------RELQIMRKLDH 106
IG G++GVVY+ + +G +A+KK+ R + RE+ ++R+L H
Sbjct: 319 IGEGTYGVVYKCRHRATGRKLAMKKI----RLRGSEDGVPSSAIREIAMLRELRH 167
>19149
Length = 454
Score = 28.5 bits (62), Expect = 5.1, Method: Compositional matrix adjust.
Identities = 12/21 (57%), Positives = 15/21 (71%)
Frame = -3
Query: 307 PRTPPEAIALCSRLLEYTPTA 327
P+ P A+ALCSRLL TP +
Sbjct: 74 PKDPSSALALCSRLLVLTPNS 12
>32957
Length = 645
Score = 28.1 bits (61), Expect = 6.5, Method: Compositional matrix adjust.
Identities = 14/40 (35%), Positives = 21/40 (52%)
Frame = +3
Query: 215 SYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQ 254
++ +R Y APE + +Y +D W G +L ELL Q
Sbjct: 42 TFCGTREYMAPE-VHERKEYGKEVDWWGLGILLHELLAAQ 158
>26052
Length = 562
Score = 28.1 bits (61), Expect = 7.5, Method: Compositional matrix adjust.
Identities = 13/32 (40%), Positives = 20/32 (62%)
Frame = -1
Query: 56 YTDTKVIGNGSFGVVYQAKLCDSGELVAIKKV 87
Y K++G GSFG V + D+GE +A+K +
Sbjct: 385 YLFXKLLGVGSFGKVMALQHKDTGETLAVKNI 290
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000324806 | hsapiens_gene_ensembl | Glycogen
synthase kinase-3 beta (EC 2.7.11.26) (GSK-3 beta).
[Source:Uniprot/SWISSPROT;Acc:P49841]
(433 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
32359 245 2e-80
05084 208 4e-54
01707 155 2e-38
01060 135 3e-32
14126 135 4e-32
01756 117 7e-27
29581 115 4e-26
28638 75 4e-23
04591 101 5e-22
04138 99 4e-21
13592 92 3e-19
03508 89 3e-18
32000 88 8e-18
00300 85 5e-17
18921 77 1e-14
12721 76 2e-14
23319 75 5e-14
03240 75 6e-14
13066 70 1e-12
15910 69 3e-12
09606 69 4e-12
06405 68 7e-12
30755 67 2e-11
19301 66 3e-11
18484 65 4e-11
01966 65 6e-11
09007 64 9e-11
26560 64 1e-10
14116 62 3e-10
12453 62 4e-10
31885 62 4e-10
12786 62 5e-10
18287 61 1e-09
01718 60 1e-09
01392 60 2e-09
27546 59 3e-09
14420 59 5e-09
31489 57 1e-08
13212 57 1e-08
03294 55 6e-08
17975 55 7e-08
27405 54 2e-07
07940 52 4e-07
26711 52 4e-07
18401 52 5e-07
19761 51 7e-07
11185 51 8e-07
19094 51 9e-07
21433 50 2e-06
14477 49 4e-06
00715 49 4e-06
04852 47 1e-05
28157 47 2e-05
21808 46 2e-05
11404 45 5e-05
21079 45 8e-05
12672 44 1e-04
16708 42 3e-04
07291 40 0.002
00638 40 0.002
13078 40 0.002
36481 40 0.003
16003 39 0.004
26009 39 0.006
01106 38 0.009
21800 38 0.010
25019 38 0.010
29360 36 0.023
20152 36 0.024
02638 35 0.063
00486 34 0.12
37602 33 0.22
18481 32 0.44
35032 32 0.62
38560 31 1.0
19248 30 1.8
32357 30 1.8
24241 30 1.9
19149 28 5.1
32957 28 6.4
26052 28 7.7
>32359
Length = 928
Score = 245 bits (625), Expect(3) = 2e-80, Method: Compositional matrix adjust.
Identities = 113/131 (86%), Positives = 126/131 (96%)
Frame = -1
Query: 44 PGQGPDRPQEVSYTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRELQIMRK 103
GQGPDRPQEVSYTD KVIGNGSFGVVYQAKL D+ ELVAIKKVLQDKRFKNRELQIMRK
Sbjct: 460 SGQGPDRPQEVSYTDAKVIGNGSFGVVYQAKLVDTSELVAIKKVLQDKRFKNRELQIMRK 281
Query: 104 LDHCNIVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMY 163
L+H NIV+L++FFYSSGEKKDEV+LNLVL+YVPETVYRVARHYS++KQT+P++Y+KLYMY
Sbjct: 280 LEHQNIVKLKFFFYSSGEKKDEVFLNLVLEYVPETVYRVARHYSKSKQTIPILYIKLYMY 101
Query: 164 QLFRSLAYIHS 174
QLFRSLAYIHS
Sbjct: 100 QLFRSLAYIHS 68
Score = 49.7 bits (117), Expect(3) = 2e-80, Method: Compositional matrix adjust.
Identities = 28/43 (65%), Positives = 31/43 (72%)
Frame = -2
Query: 1 MSGRPRTTSFAESCKPVQQPSAFGSMKVSRDKDGSKVTTVVAT 43
MSGRPRTTSFAE KP Q + FG M+ KDG KVTTV+AT
Sbjct: 582 MSGRPRTTSFAEGGKPGQN-APFGGMRTI-SKDGGKVTTVLAT 460
Score = 44.3 bits (103), Expect(3) = 2e-80, Method: Compositional matrix adjust.
Identities = 18/21 (85%), Positives = 20/21 (95%)
Frame = -3
Query: 176 GICHRDIKPQNLLLDPDTAVL 196
G+CHRDIKPQNLLLDP+T VL
Sbjct: 65 GVCHRDIKPQNLLLDPETGVL 3
>05084
Length = 1324
Score = 208 bits (529), Expect = 4e-54, Method: Compositional matrix adjust.
Identities = 102/140 (72%), Positives = 111/140 (79%)
Frame = +2
Query: 257 FPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHPWTKDSSGTGHFTSGVR 316
PGDSGVDQLVEIIKVLGTPTREQIREMNPNY+EFKFPQIKAHPWTK
Sbjct: 2 LPGDSGVDQLVEIIKVLGTPTREQIREMNPNYSEFKFPQIKAHPWTK------------- 142
Query: 317 VFRPRTPPEAIALCSRLLEYTPTARLTPLEACAHSFFDELRDPNVKLPNGRDTPALFNFT 376
VFRPRTPPEAI L SRLLEYTP+AR+ P+EACAH+FFDELRDP +LPNGR+ P LF+FT
Sbjct: 143 VFRPRTPPEAIQLVSRLLEYTPSARIQPMEACAHAFFDELRDPASRLPNGRELPPLFSFT 322
Query: 377 TQELSSNPPLATILIPPHAR 396
EL+ P L LIPPHAR
Sbjct: 323 QMELAIAPQLNASLIPPHAR 382
>01707
Length = 757
Score = 155 bits (393), Expect = 2e-38, Method: Compositional matrix adjust.
Identities = 91/227 (40%), Positives = 129/227 (56%), Gaps = 7/227 (3%)
Frame = +1
Query: 55 SYTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQD------KRFKNRELQIMRKLDHCN 108
Y IG GS+GVV++ + ++ +LVAIKK ++ K+ RE++++++L H N
Sbjct: 67 KYEKIGKIGEGSYGVVFKCRNKETSQLVAIKKFVESEDDPLIKKIAMREIRMLKQLKHPN 246
Query: 109 IVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRS 168
+VRL F L+LV DYV T+ Y R LP VK +YQ +
Sbjct: 247 LVRLIEVFRRKKR------LHLVFDYVDHTLLNELDRYPRG---LPEPMVKRIIYQTLLA 399
Query: 169 LAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVR-GEPNVSYICSRYYRAPEL 227
+ + H + HRD+KP+N+L+ V KLCDFG A+ L G+ Y+ +R+YRAPEL
Sbjct: 400 VNFCHQYNTIHRDVKPENILITRQGQV-KLCDFGFARILTGPGDEYTDYVATRWYRAPEL 576
Query: 228 IFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLG 274
+ G T Y +DVW+ GCV AELL GQ ++PG S VDQL I K LG
Sbjct: 577 LVGDTQYGPPVDVWAIGCVFAELLTGQALWPGRSDVDQLHLIRKTLG 717
>01060
Length = 1800
Score = 135 bits (340), Expect = 3e-32, Method: Compositional matrix adjust.
Identities = 98/320 (30%), Positives = 155/320 (48%), Gaps = 23/320 (7%)
Frame = +1
Query: 57 TDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKN----------RELQIMRKLDH 106
TD + IG G++GVVY+ + +G +A+KK+ R + RE+ ++R+L H
Sbjct: 82 TDFQKIGEGTYGVVYKCRHRATGRKLAMKKI----RLRGSEDGVPSSAIREIAMLRELRH 249
Query: 107 CNIVRL--------RYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYV 158
NIV L R F D L + +D PE V R V
Sbjct: 250 TNIVCLEDVIMEDERLFLVFEFLSMD---LKMYIDKFPEGVVLDRR------------LV 384
Query: 159 KLYMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSY-- 216
K Y++Q+ + + H I HRD+KPQNLL++ T +K+ DFG A+ P +Y
Sbjct: 385 KSYVFQIVTGIXFCHQRRIVHRDLKPQNLLIN-HTGAIKIADFGMARTF--ALPVRAYTH 555
Query: 217 -ICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGT 275
+ + +YRAPE++ GA+ Y++ +DVWS G + A++L+ PIF GDS +DQL +I +++GT
Sbjct: 556 EVVTLWYRAPEILMGASKYSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGT 735
Query: 276 PTREQIREMNPNYTEF-KFPQIKA-HPWTKDSSGTGHFTSGVRVFRPRTPPEAIALCSRL 333
PT + + EF K P P K+ + T + L R
Sbjct: 736 PTEQ-------TWPEFHKLPAFNGMFPLWKEGKLSETLTD--------LDSLGLDLIERT 870
Query: 334 LEYTPTARLTPLEACAHSFF 353
L+ P R++ + H++F
Sbjct: 871 LKCDPAQRISCKKMLQHAYF 930
>14126
Length = 1265
Score = 135 bits (339), Expect = 4e-32, Method: Compositional matrix adjust.
Identities = 93/280 (33%), Positives = 147/280 (52%), Gaps = 15/280 (5%)
Frame = +3
Query: 12 ESCKPVQQPSAFGSMKVSRDKDGSKVTTVVATPGQGPDRPQEVSYTDTKVIGNGSFGVVY 71
E P P A SMK + G + A E Y + VIGNG++G VY
Sbjct: 66 EESSPKTSP-AVRSMKTAISPKGRDGQSESAAKMSRRRDSTEQKYEEVAVIGNGAYGTVY 242
Query: 72 QAK-LCDSGELVAIKKVLQDKRFKN----------RELQIMRKLD---HCNIVRLRYFFY 117
+A+ L + GE VA+K++ R N RE+ ++++L+ H N+VRL +
Sbjct: 243 KARDLRNQGEFVAMKRI----RLNNTEEGMPMMAIREISMLKQLEQYEHPNVVRLLDVSH 410
Query: 118 SSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQ-TLPVIYVKLYMYQLFRSLAYIHSFG 176
++ + E+ LNLV +Y+ + +A + ++ L +K M QL + ++HS
Sbjct: 411 NTITDR-EIRLNLVFEYIE---HDLATYLAKCPSPGLGPDRIKDLMLQLLNGVDFLHSNR 578
Query: 177 ICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTS 236
I HRD+KPQNLL+ D LKL DFG A+ + + + +YR+PE++ A +Y +
Sbjct: 579 IVHRDLKPQNLLISKD-GRLKLADFGLARIYSFHMALTTVVVTLWYRSPEVLMQA-EYGT 752
Query: 237 SIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTP 276
S+D+WS GC+ AEL + +F G S DQL +I +V+G P
Sbjct: 753 SVDIWSCGCIFAELFTRRALFKGSSEFDQLKKIFEVIGLP 872
>01756
Length = 1858
Score = 117 bits (294), Expect = 7e-27, Method: Compositional matrix adjust.
Identities = 79/242 (32%), Positives = 125/242 (51%), Gaps = 14/242 (5%)
Frame = -3
Query: 52 QEVSYTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKN------RELQIMRKLD 105
++ Y IG G+FG V++A+ + ++VA+KKVL D + RE++I++ L+
Sbjct: 1748 EDAKYEKLAKIGQGTFGEVFKARCKKTKQVVAMKKVLMDNEKEGFPITALREIKILQLLN 1569
Query: 106 HCNIVRLRYF----FYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLY 161
H N+V L S+ K YL V ++ + +A S + +K
Sbjct: 1568 HENVVDLIEICSTKATSANRYKSMFYL--VFEFCE---HDLAGLLSNMSVVFNLPEIKEV 1404
Query: 162 MYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRG--EPN--VSYI 217
M QL L YIH I HRD+K N+L+ VLKL DFG A+ +PN + +
Sbjct: 1403 MKQLMNGLYYIHRNKILHRDMKAANILITKQ-GVLKLADFGLARAFSVNLRQPNRYTNRV 1227
Query: 218 CSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPT 277
+ +YR PEL+ G +Y+++ID W AGC++AE+ PI G + +QL I ++ G+ T
Sbjct: 1226 VTLWYRPPELLLGDRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQNQLTLITQLCGSIT 1047
Query: 278 RE 279
E
Sbjct: 1046 PE 1041
>29581
Length = 1278
Score = 115 bits (287), Expect = 4e-26, Method: Compositional matrix adjust.
Identities = 81/264 (30%), Positives = 135/264 (51%), Gaps = 8/264 (3%)
Frame = -2
Query: 100 IMRKLDHCNIVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARH----YSRAKQTLPV 155
+ L H NIV+L+ G+ D ++L V++Y + + + + +S ++
Sbjct: 1196 FLLNLRHQNIVQLQEVVV--GKSLDSLFL--VMEYCEQDLASLLDNMPAPFSESQ----- 1044
Query: 156 IYVKLYMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGE-PNV 214
VK + QL + L Y+H I HRD+K NLL+ D +K+ DFG A+ + + P
Sbjct: 1043 --VKCIVLQLLKGLRYLHEAFIIHRDLKVSNLLMT-DKGCVKIADFGLARNYGKPQKPMT 873
Query: 215 SYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLG 274
+ + +YRAPEL+FG+ ++++ID+WSAGC+L ELL +P+ PG S + Q+ I+++LG
Sbjct: 872 PKVVTLWYRAPELLFGSKTHSTAIDMWSAGCILGELLGHKPLMPGRSDLQQIELIMELLG 693
Query: 275 TPTREQIREMNPNYTEF-KFPQ--IKAHPWTKDSSGTGHFTSGVRVFRPRTPPEAIALCS 331
TP + P +++ F Q +K P+ + +R P I L +
Sbjct: 692 TPN----DTIWPGFSQLPAFEQFTLKKQPY-----------NNLRHTFPWLSESGIRLLN 558
Query: 332 RLLEYTPTARLTPLEACAHSFFDE 355
L Y P R T + HS+F E
Sbjct: 557 GLFMYHPQKRATAEDCLEHSYFKE 486
>28638
Length = 1458
Score = 75.5 bits (184), Expect(3) = 4e-23, Method: Compositional matrix adjust.
Identities = 45/113 (39%), Positives = 70/113 (61%), Gaps = 6/113 (5%)
Frame = -1
Query: 149 AKQTLPVIYVKL---YMYQLFRSLAYIHS--FGICHRDIKPQNLLL-DPDTAVLKLCDFG 202
A QTL + + L + QL +L ++ + I H D+KP+N+LL +P + +K+ DFG
Sbjct: 867 ATQTLEGVSLNLTRKFAQQLCTALLFLATPEMNIIHCDLKPENILLCNPKRSAIKIVDFG 688
Query: 203 SAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQP 255
S+ QL G+ YI SR+YR+PE++ G Y +ID+WS GC+L E+ G+P
Sbjct: 687 SSCQL--GQRIYQYIQSRFYRSPEVLLGV-PYDLAIDMWSLGCILVEMHTGEP 538
Score = 37.4 bits (85), Expect(3) = 4e-23, Method: Compositional matrix adjust.
Identities = 33/127 (25%), Positives = 51/127 (40%), Gaps = 21/127 (16%)
Frame = -2
Query: 253 GQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFK-FPQIKAHP--------WTK 303
G P+F G + DQ+++I++VLG P R + + F P P +
Sbjct: 545 GNPLFAGSNEFDQMMKIVEVLGVPPRHILDQAQKTRKYFDLLPDGTYAPKKPRDNKKYKS 366
Query: 304 DSSGTGHFTSGVRVFRP-----RTPPEAIA-------LCSRLLEYTPTARLTPLEACAHS 351
SS H G P P +A L R+L++ P R++P A H+
Sbjct: 365 PSSRKLHEVLGAEKGGPGGRRMGEPGHTVADYLKFKDLILRMLDFDPKTRISPYYALQHN 186
Query: 352 FFDELRD 358
FF + D
Sbjct: 185 FFRKTSD 165
Score = 33.1 bits (74), Expect(3) = 4e-23, Method: Compositional matrix adjust.
Identities = 32/99 (32%), Positives = 47/99 (47%), Gaps = 10/99 (10%)
Frame = -3
Query: 56 YTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRE------LQIMRKLDHCN- 108
Y +IG GSFG V +A E VAIK + K F N+ L++M + D N
Sbjct: 1141 YEIDSLIGKGSFGQVVKAYDHGDQEQVAIKIIKNKKPFLNQAQIEVKLLELMNRHDADNX 962
Query: 109 --IVRL-RYFFYSSGEKKDEVYLNLVLDYVPETVYRVAR 144
IVRL R+F + + +L LV + + +Y + R
Sbjct: 961 YYIVRLKRHFMFRN-------HLCLVFELLSYNLYDLLR 866
>04591
Length = 1117
Score = 101 bits (252), Expect = 5e-22, Method: Compositional matrix adjust.
Identities = 62/188 (32%), Positives = 99/188 (52%), Gaps = 4/188 (2%)
Frame = -2
Query: 96 RELQIMRKLDHCNIVRLRYFFYSSG----EKKDEVYLNLVLDYVPETVYRVARHYSRAKQ 151
RE++I+++L+H N+V+L+ ++ K YL + +Y Y +A + +
Sbjct: 1074 REIKILQQLEHENVVQLQEICHTQAGPYNRYKSTFYL--IFEYCD---YDLAGLLNNLRV 910
Query: 152 TLPVIYVKLYMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGE 211
+ K M QL L YIH+ I HRDIK N+LL D VLKL DFG ++ V+ +
Sbjct: 909 KFSLADKKNLMSQLLNGLFYIHTKQILHRDIKAANILLTRD-GVLKLADFGLSRPWVKSK 733
Query: 212 PNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIK 271
+ + + +YR PEL+ G +Y ID+W GC++AE+ +P+ G S QL I
Sbjct: 732 RLTNRVVTLWYRPPELLLGEREYGPEIDMWGVGCIMAEMWSRKPLMQGRSEQHQLSLITD 553
Query: 272 VLGTPTRE 279
+ G+ E
Sbjct: 552 LCGSLNAE 529
>04138
Length = 800
Score = 98.6 bits (244), Expect = 4e-21, Method: Compositional matrix adjust.
Identities = 65/190 (34%), Positives = 98/190 (51%), Gaps = 5/190 (2%)
Frame = +1
Query: 169 LAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRG--EPN--VSYICSRYYRA 224
L YIH I HRD+K N+L+ VLKL DFG A+ +PN + + + +YR
Sbjct: 52 LYYIHRNKILHRDMKAANILITKQ-GVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRP 228
Query: 225 PELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREM 284
PEL+ G +Y+++ID W AGC++AE+ PI G + +QL I ++ G+ T E+
Sbjct: 229 PELLLGDRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQNQLTLITQLCGSIT----PEV 396
Query: 285 NPNYTEFK-FPQIKAHPWTKDSSGTGHFTSGVRVFRPRTPPEAIALCSRLLEYTPTARLT 343
P T+ + QIK ++G + R R P + L RLL+ P+ R++
Sbjct: 397 WPGVTQLSMYHQIKGAL----AAGRKNIIRD-RFARILKDPYGLDLFERLLKMDPSQRIS 561
Query: 344 PLEACAHSFF 353
EA H FF
Sbjct: 562 ADEALNHDFF 591
>13592
Length = 980
Score = 92.4 bits (228), Expect = 3e-19, Method: Compositional matrix adjust.
Identities = 66/207 (31%), Positives = 106/207 (51%), Gaps = 14/207 (6%)
Frame = +2
Query: 62 IGNGSFGVVYQAKLCDSGELVAIKKVL----QDKRFKN--RELQIMRKLDHCNIVRLRYF 115
IG G FG VY A ++GEL+A+K++ + + KN EL+I+ + H N+VR Y+
Sbjct: 8 IGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETRALKNVAEELKILEGIKHKNLVR--YY 181
Query: 116 FYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSF 175
++ +++ L + E++ + LP + + QL +A +H
Sbjct: 182 GIEVHREELLIFMELCSEGTLESLVELT-------GGLPEALSRRFTAQLLSGVAELHKH 340
Query: 176 GICHRDIKPQNLLLDPDTAVLKLCDFGSAKQL-----VRGEPNVSYICSRYYRAPELIFG 230
GI HRDIK N+ L + LKL DFGSA ++ V GE Y+ ++ Y APE +F
Sbjct: 341 GIVHRDIKTANIFLVDGSNSLKLGDFGSAVKIQAHTTVPGELQ-GYVGTQAYMAPE-VFT 514
Query: 231 ATD---YTSSIDVWSAGCVLAELLLGQ 254
T+ + D+WS GCV+ E+ G+
Sbjct: 515 KTNSDGHGRLADIWSVGCVVVEMASGK 595
>03508
Length = 1463
Score = 89.0 bits (219), Expect = 3e-18, Method: Compositional matrix adjust.
Identities = 42/115 (36%), Positives = 70/115 (60%), Gaps = 2/115 (1%)
Frame = +1
Query: 146 YSRAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAK 205
+ + QT ++ Y+Y+L ++L + HS GI HRD+KP N+++D + L+L D+G A+
Sbjct: 841 FKQLYQTFTDYDIRFYLYELMKALDFCHSMGIMHRDVKPHNVMIDHENKKLRLIDWGLAE 1020
Query: 206 QLVRG-EPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLL-GQPIFP 258
G E NV + SRY++ PEL+ Y S+D+WS GC+ A ++ +P+ P
Sbjct: 1021FYHPGMEYNVR-VASRYFKGPELLLDYQMYDYSLDMWSLGCMFASMIFRKEPLLP 1182
Score = 42.4 bits (98), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 38/118 (32%), Positives = 45/118 (38%), Gaps = 4/118 (3%)
Frame = +2
Query: 240 VWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAH 299
VW+A C+ A P F G DQLV I KVLGT + Y + QI
Sbjct: 1130 VWAA-CLPA*SSGKSPFFHGHDNYDQLVRIAKVLGT---------DDLYGYIEKYQIDLD 1279
Query: 300 PWTKDSSGTGHFTSGVRVFRPRT----PPEAIALCSRLLEYTPTARLTPLEACAHSFF 353
P D G R PEA+ +LL Y RLT EA H +F
Sbjct: 1280 PRFNDILGRHSRKRWERFVHSENQHLISPEALDFLDKLLRYDHNERLTAREAMDHPYF 1453
>32000
Length = 644
Score = 87.8 bits (216), Expect = 8e-18, Method: Compositional matrix adjust.
Identities = 54/170 (31%), Positives = 88/170 (51%), Gaps = 5/170 (2%)
Frame = -1
Query: 193 TAVLKLCDFGSAKQLVRGEPNVSY---ICSRYYRAPELIFGATDYTSSIDVWSAGCVLAE 249
TA +K+ DFG A+ V G P +Y + + +YRAPE++ G Y+ +D+WS GC+ E
Sbjct: 581 TAKMKIADFGLAR--VFGLPVRTYTHEVITLWYRAPEILLGCRFYSVPVDIWSLGCIFVE 408
Query: 250 LLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFK--FPQIKAHPWTKDSSG 307
++ + +FPGDS +DQL I + LGTP E++ ++K FP+ W +
Sbjct: 407 MMTRRALFPGDSEIDQLYRIFRTLGTPD-EKVWPGVSKLPDYKPTFPK-----WPLKNLE 246
Query: 308 TGHFTSGVRVFRPRTPPEAIALCSRLLEYTPTARLTPLEACAHSFFDELR 357
T S V + L R+L Y P R++ A H +F++++
Sbjct: 245 TVVSLSKV----------GLDLLKRMLTYNPNRRISARSAMRHPYFNDMK 126
>00300
Length = 2318
Score = 85.1 bits (209), Expect = 5e-17, Method: Compositional matrix adjust.
Identities = 72/242 (29%), Positives = 116/242 (47%), Gaps = 19/242 (7%)
Frame = -1
Query: 32 KDGSKVTTVVATPGQGPD-----RPQEVSYTDTKVIGNGSFGVVYQAKLCDSGELVAIKK 86
++ S++ V A P + PD R + IG G FG VY A +GEL+A+K+
Sbjct: 1736 QEKSRIGRVAAKPRE-PDYRINVRRVNFRWQRGNKIGEGQFGKVYTAVNMSTGELMALKE 1560
Query: 87 V------LQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSGEKKDEVYLNLVLDYVPETVY 140
+ LQ R E++I + H N+V+ +Y KDE+ + ++Y
Sbjct: 1559 MKFQPNDLQQLREMCDEIKIFEGIQHENLVK----YYGVEVHKDEMLM--FMEYCDTGTI 1398
Query: 141 RVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCD 200
A AK LP ++ Y ++ ++ ++H I HRDIK N+ L + V KL D
Sbjct: 1397 EEA-----AKMGLPEYLIRRYTREIVLAVNHLHENSIVHRDIKGANIFLTSNGHV-KLGD 1236
Query: 201 FGSAKQL-----VRGEPNVSYICSRYYRAPELIFGATD---YTSSIDVWSAGCVLAELLL 252
FG + +L + GE + + + + Y APE +F D Y + D+WS GCV+ E+
Sbjct: 1235 FGCSVKLKSHTTMPGEFH-NLVGTTAYMAPE-VFTQNDQGGYGRAADIWSLGCVVIEMAT 1062
Query: 253 GQ 254
G+
Sbjct: 1061 GK 1056
>18921
Length = 697
Score = 77.0 bits (188), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 65/211 (30%), Positives = 109/211 (51%), Gaps = 5/211 (2%)
Frame = +2
Query: 50 RPQEVSYTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKN--RELQIMRKLDHC 107
RP E + +G GS+G V+++ ++G+++AIK+V D + +E+ IM++ D
Sbjct: 17 RPPEDVFDILGKLGEGSYGSVFKSLHKETGQVLAIKQVPVDTDLQEIIKEISIMQQCDSK 196
Query: 108 NIVRLRYFFYSSGEKKDEVYLNLVLDYV-PETVYRVARHYSRAKQTLPVIYVKLYMYQLF 166
IV+ +Y S K ++++ V++Y +V + R ++ TL + +Y
Sbjct: 197 YIVK----YYGSYFKNTDLWI--VMEYCGAGSVSDIMRLRNK---TLVEREIATILYYTL 349
Query: 167 RSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQL--VRGEPNVSYICSRYYRA 224
+ L Y+HS HRDIK N+LL+ + KL DFG A QL + N + I + Y+ A
Sbjct: 350 KGLXYLHSRRKIHRDIKAGNILLNNEGHA-KLADFGVAGQLTDTMAKRN-TVIGTPYWMA 523
Query: 225 PELIFGATDYTSSIDVWSAGCVLAELLLGQP 255
PE+I Y D+WS G E+ G+P
Sbjct: 524 PEVI-QEIGYDCVADIWSLGITALEMAEGKP 613
>12721
Length = 821
Score = 76.3 bits (186), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 62/207 (29%), Positives = 104/207 (50%), Gaps = 7/207 (3%)
Frame = +1
Query: 58 DTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNR------ELQIMRKLDHCNIVR 111
D IG GS G+V A D G +A+KK+ D R + R E+ +MR H NIV
Sbjct: 100 DFMKIGEGSTGIVCIATSRD-GRQMAVKKM--DLRKQQRRELLFNEVVVMRDYHHPNIVE 270
Query: 112 LRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAY 171
+ Y+S DE+++ V++++ +R + + + ++LA+
Sbjct: 271 M----YNSYLVNDELWV--VMEFMEGGALTDIVTNNRMDE----VQIATVCRACLKALAF 420
Query: 172 IHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRG-EPNVSYICSRYYRAPELIFG 230
+H+ G+ HRDIK ++LL D V KL DFG Q+ + + S + + Y+ APE+I
Sbjct: 421 LHANGVIHRDIKSDSILLSHDGKV-KLXDFGFCAQVTQDLQKRKSLVGTPYWMAPEVI-S 594
Query: 231 ATDYTSSIDVWSAGCVLAELLLGQPIF 257
Y +D+WS G ++ E++ +P F
Sbjct: 595 RLPYGPEVDIWSLGIMVMEMIDAEPPF 675
>23319
Length = 2235
Score = 75.1 bits (183), Expect = 5e-14, Method: Compositional matrix adjust.
Identities = 47/132 (35%), Positives = 67/132 (50%), Gaps = 3/132 (2%)
Frame = +3
Query: 228 IFGATDYTSSIDVWSAGCVLAELL-LGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMN- 285
++ A Y++SID+WSAGC+ AEL G+P+FPG+ DQL I K+LGTPT +Q M
Sbjct: 9 VYXAKMYSTSIDMWSAGCIFAELANAGRPLFPGNDDDDQLKRIFKLLGTPTEDQWPGMTQ 188
Query: 286 -PNYTEFKFPQIKAHPWTKDSSGTGHFTSGVRVFRPRTPPEAIALCSRLLEYTPTARLTP 344
PNY F H T+ + P+ + L LL P+ R++
Sbjct: 189 LPNYRMFPM---------------YHVTTTWQQVVPKLNSKGRDLLQCLLVCCPSDRMSA 323
Query: 345 LEACAHSFFDEL 356
EA H +F +L
Sbjct: 324 DEALQHPYFADL 359
>03240
Length = 1683
Score = 75.1 bits (183), Expect = 6e-14, Method: Compositional matrix adjust.
Identities = 68/269 (25%), Positives = 113/269 (42%), Gaps = 54/269 (20%)
Frame = -3
Query: 56 YTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNR-------ELQIMRKLDHCN 108
+ K +G G+FG V + D+G L A+K + + K E I+ + D+
Sbjct: 1285 FEKIKTLGVGAFGEVSLCRKNDTGMLYAMKTLRKSDVLKRNQVAHVKAERDILAEADNEW 1106
Query: 109 IVRLRYFFYSSGEKKDEVYLNLVLDYVP--ETVYRVARHYSRAKQTLPVIYVKLYMYQLF 166
+V+L Y F +D YL V+DYVP + + + R + L + Y+ +L
Sbjct: 1105 VVKLYYSF------QDHNYLYFVMDYVPGGDLMGLLIR-----MEILDEPLARFYVAELV 959
Query: 167 RSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFG---------SAKQLVRGEPNV--- 214
+++ +H G HRDIKP N+L+D + + KL DFG ++K R +
Sbjct: 958 QAIESVHRMGFIHRDIKPDNILIDRNGHI-KLTDFGLCTGFRWTHNSKYYQRDGTHARQD 782
Query: 215 ---------------------------------SYICSRYYRAPELIFGATDYTSSIDVW 241
S + + Y APE++ YTS D W
Sbjct: 781 SMEVKCQLDEQCQCEILKPLERRRKREQRCLAHSLVGTPNYIAPEVLSRLGGYTSVCDWW 602
Query: 242 SAGCVLAELLLGQPIFPGDSGVDQLVEII 270
S G +L E+L+G P F ++ + ++I
Sbjct: 601 SVGVILFEMLVGHPPFYANTPAETQYKVI 515
>13066
Length = 551
Score = 70.5 bits (171), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 59/199 (29%), Positives = 96/199 (48%), Gaps = 15/199 (7%)
Frame = +3
Query: 61 VIGNGSFGVVYQAKLCDSGELVAIKKVLQD--KRFKNRELQIMRKLDHCNIVRLR----- 113
V+ +G+F Y + + +++ +K D ++F REL ++ KLDH I+++
Sbjct: 12 VVVHGTFNDGYGRNIKLACKIIDKEKAPVDFVEKFFPRELDLLTKLDHPYIIQIHSILQR 191
Query: 114 ----YFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSL 169
+ F E+ D +L Y+ E + + KQ K++ YQ+ +L
Sbjct: 192 XPKNFIFMRFAERGD------LLTYIQEV------GFVKEKQA------KIWFYQMTTAL 317
Query: 170 AYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLV--RGEPNVS--YICSRYYRAP 225
Y+HS+ + HRD+K +N+LL V KL DFG A + GE +S Y S Y AP
Sbjct: 318 NYLHSYDVAHRDLKCENILLSSHFNV-KLADFGFACACITESGEKYMSRTYCGSAAYAAP 494
Query: 226 ELIFGATDYTSSIDVWSAG 244
E+++GA D WS G
Sbjct: 495 EIVYGAPYAPKVADAWSLG 551
>15910
Length = 1361
Score = 69.3 bits (168), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 41/110 (37%), Positives = 64/110 (58%), Gaps = 3/110 (2%)
Frame = +2
Query: 165 LFRSLAYIHSFGICHRDIKPQNLLLD--PDTAVLKLCDFGSAKQLVRGEPNVSYICSR-Y 221
+ + YIH+ G+ HRD+KP+NLL + D + LKL DFG ++ ++ E +S +C
Sbjct: 491 ILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLADFGLSR-IIEPEVQMSTVCGTPG 667
Query: 222 YRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIK 271
Y APE++ G YT S+D+WS G + LL G F ++ + +IIK
Sbjct: 668 YCAPEVLKG-DKYTPSVDMWSVGVIAYILLCGYEPFFAENEFEMYRKIIK 814
>09606
Length = 1300
Score = 68.9 bits (167), Expect = 4e-12, Method: Compositional matrix adjust.
Identities = 78/319 (24%), Positives = 134/319 (42%), Gaps = 27/319 (8%)
Frame = -3
Query: 62 IGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFK-NRELQIMRKLDHCNIVRLRYFFYSSG 120
+G G ++Y+ + + VAI + + KR + +++ + H N+V+ ++ +S
Sbjct: 1091 LGKGEHSIIYKGRRKGTINFVAIHCIEKCKRPEVTNTVRMTHDISHPNVVQFHEWYETSN 912
Query: 121 EKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHR 180
+L LV++ T +A ++ LP ++ + L L YIHS GI
Sbjct: 911 ------HLWLVVELC--TGGSLADILAQDHH-LPETSIRDFGIHLVTGLHYIHSLGILFH 759
Query: 181 DIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRY------------------- 221
D++P +LLD + VLK DFG +K V GE N+ + ++
Sbjct: 758 DLRPSKVLLDT-SGVLKFADFGLSK--VEGE-NLEELFFKFAEAGDQWNIQSAEEMMKQV 591
Query: 222 -------YRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLG 274
Y APE+ GA S D+W+ GCV E+ G P F G++ +I
Sbjct: 590 PTSGSPTYMAPEVFQGAEPSIMS-DLWALGCVFYEMFSGHPPFLGET-----YDI----- 444
Query: 275 TPTREQIREMNPNYTEFKFPQIKAHPWTKDSSGTGHFTSGVRVFRPRTPPEAIALCSRLL 334
T++++ EF P++K G R+ + PE + L LL
Sbjct: 443 --TKDKVLN-----KEFPLPKVK----------------GSRL-SAKPSPEFLNLLESLL 336
Query: 335 EYTPTARLTPLEACAHSFF 353
+ T RL+ H+F+
Sbjct: 335 QKDSTRRLSWASLVKHAFW 279
>06405
Length = 1965
Score = 68.2 bits (165), Expect = 7e-12, Method: Compositional matrix adjust.
Identities = 64/238 (26%), Positives = 118/238 (49%), Gaps = 12/238 (5%)
Frame = +1
Query: 48 PDRPQEVSYTDTKV---IGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKN---RELQIM 101
PDR E+ T+ + +G G +G VY+A ++VA+K + +D N E IM
Sbjct: 235 PDR-WEIERTEIAMKHRLGGGQYGDVYEAMWKRYNKIVAVKTLKEDTMALNDFLEEAAIM 411
Query: 102 RKLDHCNIVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLY 161
+++ H N+V+L G E +V +++P S ++ P +Y
Sbjct: 412 KEMKHPNLVQLL------GVCTREPPFYIVTEFMPHGNLLDYLRSSTREENGPTAL--MY 567
Query: 162 MY-QLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSR 220
M Q+ +AY+ + HRD+ +N L+ D+ ++K+ DFG A+ L++ + ++I ++
Sbjct: 568 MATQIASGMAYLETKNFIHRDLAARNCLVA-DSNMVKVADFGLAR-LMKDDTYTAHIGAK 741
Query: 221 Y---YRAPE-LIFGATDYTSSIDVWSAGCVLAELL-LGQPIFPGDSGVDQLVEIIKVL 273
+ + APE L F +++ D+W+ G +L EL G +PG +L E+ +L
Sbjct: 742 FPIKWTAPEGLAFNR--FSTRSDIWAFGVLLWELATYGMSPYPG----VELTEVYHLL 897
>30755
Length = 1137
Score = 66.6 bits (161), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 37/108 (34%), Positives = 60/108 (55%), Gaps = 2/108 (1%)
Frame = +2
Query: 158 VKLYMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQ-LVRGEPNVSY 216
+ Y ++ +L Y+HS GI +RD+K +NLLLD D + K+ DFG K+ + G ++
Sbjct: 38 TRFYGAEIISALGYLHSQGIIYRDLKLENLLLDKDGHI-KVADFGLCKEDITYGRTTKTF 214
Query: 217 ICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQ-PIFPGDSGV 263
+ Y APE + DY ++D W G V+ E++ G+ P + D V
Sbjct: 215 CGTPEYLAPE-VLDDNDYGRAVDWWGTGVVMYEMICGRLPFYNRDHDV 355
>19301
Length = 712
Score = 65.9 bits (159), Expect = 3e-11, Method: Compositional matrix adjust.
Identities = 46/150 (30%), Positives = 78/150 (52%)
Frame = +2
Query: 55 SYTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRY 114
S TD + +G+G+ G V+ KLC E VA+KKV + K +++ +RKL+H NI+ +
Sbjct: 308 SITDLEWLGSGAQGAVFLGKLC--AEEVAVKKV---RDIKETDIRNLRKLNHPNIISFK- 469
Query: 115 FFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHS 174
G ++++Y P Y R + +P V + Q+ + Y+HS
Sbjct: 470 -----GVCTQAPCYCIIMEYCP---YGQLYEVLRDGKEIPPALVLDWSKQIASGMNYLHS 625
Query: 175 FGICHRDIKPQNLLLDPDTAVLKLCDFGSA 204
I HRD+K N+L+ + V+K+ DFG++
Sbjct: 626 HKIIHRDLKSPNVLVAKND-VVKISDFGTS 712
>18484
Length = 635
Score = 65.5 bits (158), Expect = 4e-11, Method: Compositional matrix adjust.
Identities = 40/125 (32%), Positives = 66/125 (52%), Gaps = 1/125 (0%)
Frame = +1
Query: 137 ETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVL 196
+ +YR+ + K PV Y ++ L ++H GI +RD+K N++LD + +
Sbjct: 1 DLMYRIQQ---EGKFKEPV--AAFYAAEIAVGLFFLHDQGIIYRDLKLDNVMLDSEGHI- 162
Query: 197 KLCDFGSAKQLVRGEPNVSYICSR-YYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQP 255
K+ DFG K+ + G+ C Y APE++ Y+ S+D W+ G +L E+L GQP
Sbjct: 163 KIADFGMCKEGMTGDATTRTFCGTPDYIAPEIVL-YQPYSKSVDWWAYGVLLFEMLAGQP 339
Query: 256 IFPGD 260
F G+
Sbjct: 340 PFDGE 354
>01966
Length = 1735
Score = 65.1 bits (157), Expect = 6e-11, Method: Compositional matrix adjust.
Identities = 50/162 (30%), Positives = 76/162 (46%), Gaps = 11/162 (6%)
Frame = -1
Query: 96 RELQIMRKLDHCNIVRL--------RYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYS 147
RE+ ++R+L H NIV L R F D L + +D PE V R
Sbjct: 1567 REIAMLRELRHTNIVCLEDVIMEDERLFLVFEFLSMD---LKMYIDKFPEGVVLDRR--- 1406
Query: 148 RAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQL 207
VK Y++Q+ + + H I HRD+KPQNLL++ T +K+ DFG A+
Sbjct: 1405 ---------LVKSYVFQIVTGINFCHQRRIVHRDLKPQNLLIN-HTGAIKIADFGMARTF 1256
Query: 208 VRGEPNVSY---ICSRYYRAPELIFGATDYTSSIDVWSAGCV 246
P +Y + + +YRAPE++ G S+ W+ G +
Sbjct: 1255 --ALPVRAYTHEVVTLWYRAPEILMGP---QSTPPXWTCGAL 1145
Score = 62.8 bits (151), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 27/68 (39%), Positives = 42/68 (61%)
Frame = -3
Query: 218 CSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPT 277
C P GA+ Y++ +DVWS G + A++L+ PIF GDS +DQL +I +++GTPT
Sbjct: 1223 CDLVVPGPRDPHGASKYSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPT 1044
Query: 278 REQIREMN 285
+ E +
Sbjct: 1043 EQTWPEFH 1020
>09007
Length = 1440
Score = 64.3 bits (155), Expect = 9e-11, Method: Compositional matrix adjust.
Identities = 63/232 (27%), Positives = 108/232 (46%), Gaps = 15/232 (6%)
Frame = -1
Query: 35 SKVTTVVATPGQGPDRPQEVSYTDTKVIGNGSFGVVYQAKL-CDSGE--LVAIKKVLQDK 91
S+ + V P +G + +K +G G FG V QA +SGE VA+K + +DK
Sbjct: 936 SRPVSAVVRPARGKQLISKDCVALSKSLGQGHFGTVRQAIWTAESGEKVQVAVKCLSKDK 757
Query: 92 RFKN-----RELQIMRKLDHCNIVRLRYFFYSSGEKKDEVYLNLVLDYVP-ETVYRVARH 145
K+ +E IM+ LDH NIVR+ +G + LV + P ++ +
Sbjct: 756 IHKDGQEFLKETAIMQMLDHENIVRVYGVVMDNGAD-----IMLVTELAPMRSLLECVKE 592
Query: 146 YSRAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCD----- 200
S A+ V + + Q+ ++Y+ S + HRD+ +N+LL + V K+ D
Sbjct: 591 VS-ARVDFSVPRLCDFSQQVCDGMSYLESKRLVHRDLAARNILLFSKSKV-KISDVGVSG 418
Query: 201 -FGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELL 251
G+ K+ + + + + + APE F ++S+ DVW+ G +L E
Sbjct: 417 ALGAGKEYYQSQQTIHLQNAVAWCAPE-SFRNLCFSSASDVWAFGVLLWEFF 265
>26560
Length = 398
Score = 63.9 bits (154), Expect = 1e-10, Method: Composition-based stats.
Identities = 37/113 (32%), Positives = 62/113 (54%), Gaps = 4/113 (3%)
Frame = -1
Query: 158 VKLYMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYI 217
V+ Y ++ L ++HS + +RD+KP N+LLD + V ++ D G A + P+ S +
Sbjct: 350 VRFYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHV-RISDLGLACDFSKKRPHAS-V 177
Query: 218 CSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIF----PGDSGVDQL 266
+ Y APE++ Y SS D +S GC+L +LL G F G + +D++
Sbjct: 176 GTHGYMAPEVLMKGQSYDSSADWFSFGCMLYKLLKGHSPFRQHNQGQARIDRM 18
>14116
Length = 1017
Score = 62.4 bits (150), Expect = 3e-10, Method: Compositional matrix adjust.
Identities = 61/211 (28%), Positives = 90/211 (42%), Gaps = 21/211 (9%)
Frame = -1
Query: 62 IGNGSFGVVYQAKLC---DSGELVAIKKVLQDKRFKNRELQ-------IMRKLDHCNIVR 111
IG G+FG V + L G+++ K L + + ELQ IM+ H N++
Sbjct: 612 IGKGNFGCVKRGFLTLPEQKGDILVAVKTLHNNNPREIELQSFLQEALIMKDFHHSNVLT 433
Query: 112 LRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARH-----YSRAKQTLPVIY-VKLYMYQL 165
L + + L LD +P V +H Y R Q P I + +Y +
Sbjct: 432 L-------------IGICLNLDDMPLVVLPFMKHGDLLTYIRDDQHQPTIKDLIMYGVDI 292
Query: 166 FRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSA-----KQLVRGEPNVSYICSR 220
R + Y+ HRD+ +N +LD D V K+ DFG A K+ E + + +
Sbjct: 291 ARGMDYLAGLKFVHRDLAARNCMLDEDFHV-KVADFGLARDIYEKEYYSSENKKAKLPVK 115
Query: 221 YYRAPELIFGATDYTSSIDVWSAGCVLAELL 251
+ L G +Y S DVWS G VL ELL
Sbjct: 114 WMALESLEKG--NYDSKTDVWSYGVVLWELL 28
>12453
Length = 680
Score = 62.4 bits (150), Expect = 4e-10, Method: Compositional matrix adjust.
Identities = 39/157 (24%), Positives = 68/157 (43%), Gaps = 2/157 (1%)
Frame = +3
Query: 244 GCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREM--NPNYTEFKFPQIKAHPW 301
GC+ E+ G+P+FPG + D+L I K LGTPT + + + NP++ P +
Sbjct: 9 GCIFYEMACGRPLFPGSTVEDELHLIFKTLGTPTEDSLPSISRNPDFLALNLPHYQGEAL 188
Query: 302 TKDSSGTGHFTSGVRVFRPRTPPEAIALCSRLLEYTPTARLTPLEACAHSFFDELRDPNV 361
PR + + L ++ L+Y R++ ++ HSFF+ L
Sbjct: 189 I--------------TIAPRLDSDGLDLLAKFLKYNAKIRVSAADSLKHSFFNSLGPGVH 326
Query: 362 KLPNGRDTPALFNFTTQELSSNPPLATILIPPHARIQ 398
LP DT + F L +P + + + +I+
Sbjct: 327 MLP---DTVSAFTVPGISLHRDPGIRSSSVASTGKIR 428
>31885
Length = 529
Score = 62.0 bits (149), Expect = 4e-10, Method: Compositional matrix adjust.
Identities = 54/158 (34%), Positives = 77/158 (48%), Gaps = 4/158 (2%)
Frame = -2
Query: 98 LQIMRKLDHCNIVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIY 157
+ ++ +LDH +V L Y F +DE L +V+D + R++ + + +
Sbjct: 519 VDMLTRLDHPFLVNLWYAF------QDEEDLFMVVDLF---LGGDLRYHMQQEVSFREDC 367
Query: 158 VKLYMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYI 217
VK Y+ QL L Y+ S I HRDIKP N+LLD + + DF A QL E S
Sbjct: 366 VKFYLCQLALVLDYLRSQKIVHRDIKPDNILLD-EQGHCHVTDFNIATQLEDDELATSTS 190
Query: 218 CSRYYRAPELIFGATD----YTSSIDVWSAGCVLAELL 251
+R Y APE+ A + Y +D WS G L ELL
Sbjct: 189 GTRPYMAPEVYGVAINERRGYGFPVDWWSLGVSLFELL 76
>12786
Length = 460
Score = 61.6 bits (148), Expect = 5e-10, Method: Compositional matrix adjust.
Identities = 41/135 (30%), Positives = 65/135 (48%), Gaps = 24/135 (17%)
Frame = -3
Query: 147 SRAKQT--LPVIYVKLYMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSA 204
+RAKQ L + +K Y ++ R++ +H+ G+ H D+KP N +L LKL DFG A
Sbjct: 443 ARAKQEQGLDRMMIKFYWREMLRAVKALHNEGVIHSDLKPANFMLVAGN--LKLIDFGIA 270
Query: 205 KQLVRGEPNV---SYICSRYYRAPELIFGATDYTSS-------------------IDVWS 242
L + + +V S + + Y +PE I A D ++ DVWS
Sbjct: 269 NTLQQDKTSVLKDSRVGTPSYMSPEAIMAACDDSADDSMEEDGHRTKPKYKVGVRSDVWS 90
Query: 243 AGCVLAELLLGQPIF 257
GC+L ++ G+ F
Sbjct: 89 LGCILYNMVYGRTPF 45
>18287
Length = 678
Score = 60.8 bits (146), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 41/124 (33%), Positives = 59/124 (47%)
Frame = -3
Query: 234 YTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKF 293
Y SID+WS GC+ AELL + +F V QL II ++GTP E + E
Sbjct: 673 YDYSIDIWSVGCIFAELLSRRILFQAQGPVQQLDMIINLVGTPRPEDMERA----CEGAR 506
Query: 294 PQIKAHPWTKDSSGTGHFTSGVRVFRPRTPPEAIALCSRLLEYTPTARLTPLEACAHSFF 353
I P+ + + T + S P EA+ L +R+L P R++ EA +H +
Sbjct: 505 NHILNQPFRRQNLLTLYNLS------PHATHEAVRLLTRMLILNPKNRISAEEALSHPYL 344
Query: 354 DELR 357
DE R
Sbjct: 343 DEGR 332
>01718
Length = 959
Score = 60.5 bits (145), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 52/204 (25%), Positives = 92/204 (45%), Gaps = 7/204 (3%)
Frame = +3
Query: 62 IGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKN--RELQIMRKLDHCNIVRLRYFFYSS 119
IG G F V++ +G+++A+K N RE+Q++ +L H NI+R
Sbjct: 171 IGAGFFSEVFKVTHRITGQVMALKMNTMTSNRHNMLREVQLLNRLQHANILRFMGVCVHE 350
Query: 120 GEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFGICH 179
G+ L+ + +Y+P + + + + LP L R L Y+HS H
Sbjct: 351 GQ------LHALTEYIPSG--NLEQLLEKKDEELPWTQRIQLTLGLARGLDYLHSTRFIH 506
Query: 180 RDIKPQNLLL---DPDTAVLKLCDFGSAKQLVR--GEPNVSYICSRYYRAPELIFGATDY 234
RD+ +N+L+ D + DFG A ++ + + + S Y+ APE++ G Y
Sbjct: 507 RDLTSKNILIRREDNHGYHAVIADFGLATKIPDPLDKEKLPTVGSPYWMAPEVLNGHF-Y 683
Query: 235 TSSIDVWSAGCVLAELLLGQPIFP 258
D++S G ++ E+ P P
Sbjct: 684 NERADLFSVGIIMCEITARIPADP 755
>01392
Length = 1806
Score = 60.1 bits (144), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 39/119 (32%), Positives = 61/119 (51%), Gaps = 12/119 (10%)
Frame = -1
Query: 158 VKLYMYQLFRSLAYIHSFGICHRDIKPQNLLLD--PDTAVLKLCDFGSAKQL-VRGEPN- 213
L + + R+L ++HS GI HRD+KP+N+L + D +K+CDF A + G+
Sbjct: 1785 ASLVVRHIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGISCDGDGTK 1606
Query: 214 ----VSYICSRYYRAPELIFG----ATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVD 264
++ + S Y APE++ + Y D+WS G +L +L G P F G G D
Sbjct: 1605 TPELLTPVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILYIMLCGYPPFYGQCGED 1429
>27546
Length = 426
Score = 59.3 bits (142), Expect = 3e-09, Method: Composition-based stats.
Identities = 39/126 (30%), Positives = 62/126 (49%), Gaps = 11/126 (8%)
Frame = -1
Query: 91 KRFKNRELQIMRKLDHCNIVRLR---------YFFYSSGEKKDEVYLNLVLDYVPETVYR 141
K+F REL+I+ +LDH NI+++ + F EK D +
Sbjct: 348 KKFFPRELEILTRLDHPNIIQIHSILQRGPKIFIFMRYAEKGDML--------------- 214
Query: 142 VARHYSRAKQTLPV--IYVKLYMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLC 199
S K+T P+ K++ +Q+ ++L Y+HS I HRD+K +N+LL V K+
Sbjct: 213 -----SHIKKTGPIDEAQTKVWFFQMAKALQYLHSHDIAHRDLKCENILLSKRLNV-KIA 52
Query: 200 DFGSAK 205
DFG A+
Sbjct: 51 DFGFAR 34
>14420
Length = 528
Score = 58.5 bits (140), Expect = 5e-09, Method: Compositional matrix adjust.
Identities = 32/93 (34%), Positives = 53/93 (56%), Gaps = 1/93 (1%)
Frame = +2
Query: 164 QLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVS-YICSRYY 222
+ ++L ++H + HRDIK N+LL D +V KL DFG QL + S + + Y+
Sbjct: 221 ECLQALEFLHENQVIHRDIKSDNILLGMDGSV-KLTDFGFCAQLSPEQSKRSTMVGTPYW 397
Query: 223 RAPELIFGATDYTSSIDVWSAGCVLAELLLGQP 255
APE++ Y ++D+WS G + E++ G+P
Sbjct: 398 MAPEVV-TRKQYGPTVDIWSLGVMCIEMIEGEP 493
>31489
Length = 329
Score = 57.4 bits (137), Expect = 1e-08, Method: Composition-based stats.
Identities = 29/91 (31%), Positives = 50/91 (54%)
Frame = +3
Query: 98 LQIMRKLDHCNIVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIY 157
++I++ H NI+ +R D +++V D + ++R+ YS Q L +
Sbjct: 3 IKILKHFKHDNIISIREILKPKDSYHDFKDIHVVFDLMESDLHRII--YS--DQPLTEEH 170
Query: 158 VKLYMYQLFRSLAYIHSFGICHRDIKPQNLL 188
++ ++YQ+ R L YIHS + HRD+KP NLL
Sbjct: 171 IRYFLYQILRGLKYIHSANVVHRDLKPSNLL 263
>13212
Length = 1067
Score = 57.0 bits (136), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 34/98 (34%), Positives = 51/98 (52%), Gaps = 5/98 (5%)
Frame = -1
Query: 163 YQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFG-SAKQLVRGEPNVSYICSRY 221
+++ +L ++H + HRDIK N+LL D V KL DFG SAK + ++I + Y
Sbjct: 959 HEMCMALDFLHRHHVIHRDIKAGNVLLTIDGEV-KLADFGVSAKNTQTQQKRDTFIGTPY 783
Query: 222 YRAPELI----FGATDYTSSIDVWSAGCVLAELLLGQP 255
+ APE++ T Y D+WS G L E +P
Sbjct: 782 WMAPEVVLCETLKDTPYDFKADIWSLGVTLIEFAQIEP 669
>03294
Length = 1684
Score = 54.7 bits (130), Expect = 6e-08, Method: Compositional matrix adjust.
Identities = 22/48 (45%), Positives = 34/48 (70%)
Frame = -1
Query: 238 IDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMN 285
+DVWS G + A++L+ PIF GDS +DQL +I +++GTPT + E +
Sbjct: 1672 VDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFH 1529
>17975
Length = 449
Score = 54.7 bits (130), Expect = 7e-08, Method: Compositional matrix adjust.
Identities = 42/152 (27%), Positives = 76/152 (50%), Gaps = 6/152 (3%)
Frame = +3
Query: 67 FGVVYQAKLCDSGELVAIKKVLQDK------RFKNRELQIMRKLDHCNIVRLRYFFYSSG 120
F VV A+ +GE VA+K + + K +E++ M+ + H N+VRL Y
Sbjct: 6 FAVVKLARHVFTGEKVAVKVIDKTKLDEVSRSHLFQEVRCMKLVQHPNVVRL----YEVI 173
Query: 121 EKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHR 180
+ + ++YL L L + + RH ++ L K Y Q+ +++Y H + HR
Sbjct: 174 DTQTKLYLILELGDGGDMYDYIMRHSGGLEEKLA----KRYFRQIVEAISYCHKLHVVHR 341
Query: 181 DIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEP 212
D+KP+N++ ++KL DFG + L++ +
Sbjct: 342 DLKPENVVFFEKPGLVKLTDFGFSTCLLQAKA 437
>27405
Length = 532
Score = 53.5 bits (127), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 54/190 (28%), Positives = 90/190 (47%), Gaps = 14/190 (7%)
Frame = -3
Query: 66 SFGVVYQAKLCDSGELVAIKKVLQDKRFKNR-------ELQIMRKLDHCN-----IVRLR 113
FG VY + D+G++ A+K L KR K + +IM L IV +
Sbjct: 530 GFGEVYGCRKADTGKMYAMK-CLDKKRIKMKGGETLALNERIMLSLVSTGEGSPFIVCMT 354
Query: 114 YFFYSSGEKKDEVYLNLVLDYV--PETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAY 171
Y F + EK L +LD + + Y +++H ++ V+ Y ++ L +
Sbjct: 353 YAFQTP-EK-----LCFILDLMNGGDLHYHLSQHGVFTEKE-----VRFYAAEVMLGLEH 207
Query: 172 IHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGA 231
+HS + +RD+KP N+LLD + V ++ D G A + +P+ S + + Y APE++
Sbjct: 206 MHSRFVVYRDLKPANILLDENGHV-RISDLGLACDFSKKKPHAS-VGTHGYMAPEVLMKG 33
Query: 232 TDYTSSIDVW 241
Y SS D W
Sbjct: 32 QAYDSSAD-W 6
>07940
Length = 1336
Score = 52.4 bits (124), Expect = 4e-07, Method: Compositional matrix adjust.
Identities = 36/102 (35%), Positives = 53/102 (51%), Gaps = 4/102 (3%)
Frame = -3
Query: 161 YMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSR 220
Y YQ+ R + Y+ S HRD+ +N+L+ + VLK+ DFG + L + + R
Sbjct: 332 YAYQVARGMEYLASKQCIHRDLAARNVLV-AEEYVLKIADFGLTRNLQQFDYYRKTTDGR 156
Query: 221 Y---YRAPELIFGATDYTSSIDVWSAGCVLAELL-LGQPIFP 258
+ APE +F YTS DVWS G +L E+ LG +P
Sbjct: 155 LPVKWMAPEALFD-RKYTSKSDVWSYGVLLWEIFTLGGNPYP 33
>26711
Length = 405
Score = 52.4 bits (124), Expect = 4e-07, Method: Composition-based stats.
Identities = 33/104 (31%), Positives = 53/104 (50%), Gaps = 1/104 (0%)
Frame = -2
Query: 164 QLFRSLAYIHSFGICHRDIKPQNLLLDPDTA-VLKLCDFGSAKQLVRGEPNVSYICSRYY 222
Q+ L ++H+ G+ H D+KP NLLL D ++L DFG A++L + + +
Sbjct: 392 QVLDILQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARKLYPPQETFLNHGTPGF 213
Query: 223 RAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQL 266
+PE + +++ DVW G + LL GQ F DS + L
Sbjct: 212 TSPEAL-DVKPISTASDVWGVGVLAYILLSGQSPFQADSATESL 84
>18401
Length = 463
Score = 52.0 bits (123), Expect = 5e-07, Method: Compositional matrix adjust.
Identities = 39/152 (25%), Positives = 63/152 (41%), Gaps = 15/152 (9%)
Frame = -3
Query: 217 ICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGT- 275
+ +R+YRAPE+I ++ DVWS GC++ EL G +F + L + ++LG+
Sbjct: 449 VSTRHYRAPEVIL-ELGWSHPCDVWSVGCIMFELYTGYTLFQTHDNKEHLAMMERILGSL 273
Query: 276 PTREQIREMNPNYTEFKFPQIKAHPWTKDSSGTGHFTSGVRVFRPRTPP----------- 324
P R + Y F ++ +S R R T P
Sbjct: 272 PYRMAKKTKKQKY--FHHGRL----------DVPERSSMARYVRENTKPLLRYVKDRENK 129
Query: 325 ---EAIALCSRLLEYTPTARLTPLEACAHSFF 353
+ L +LL Y ++R + L+A H FF
Sbjct: 128 DHQQLFDLMKKLLAYEASSRYSLLQALQHPFF 33
>19761
Length = 473
Score = 51.2 bits (121), Expect = 7e-07, Method: Compositional matrix adjust.
Identities = 38/128 (29%), Positives = 63/128 (49%), Gaps = 6/128 (4%)
Frame = -3
Query: 153 LPVIYVKLYMYQLFRSLAYIHSFG--ICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVR- 209
LP + ++ Q +L Y+H+ I HRD+KPQN+ + V +L D G A++L
Sbjct: 432 LPERLIVCWLMQTASALNYMHTHTPVILHRDLKPQNIYVTEKGDV-RLGDLGLARKLTGP 256
Query: 210 GEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQ---L 266
+ S + + Y +PE I Y S D+WS GCV ++ G G D+ +
Sbjct: 255 ADFATSQVGTIMYLSPE-ILSQQPYNSKSDIWSLGCVFYDI-------TGKKGSDEMGVM 100
Query: 267 VEIIKVLG 274
+++V+G
Sbjct: 99 FLLVQVMG 76
>11185
Length = 473
Score = 51.2 bits (121), Expect = 8e-07, Method: Compositional matrix adjust.
Identities = 38/116 (32%), Positives = 51/116 (43%), Gaps = 26/116 (22%)
Frame = +1
Query: 164 QLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRY-- 221
L L YIHS GI D++P +LLD + VLK DFG +K V GE N+ + ++
Sbjct: 25 HLVTGLHYIHSLGILFHDLRPSKVLLDT-SGVLKFADFGLSK--VEGE-NLEELFFKFAE 192
Query: 222 ------------------------YRAPELIFGATDYTSSIDVWSAGCVLAELLLG 253
Y APE+ GA S D+W+ GCV E+ G
Sbjct: 193 AGDQWNIQSAEEMMKQVPTSGSPTYMAPEVFQGAEPSIMS-DLWALGCVFYEMFSG 357
>19094
Length = 898
Score = 51.2 bits (121), Expect = 9e-07, Method: Compositional matrix adjust.
Identities = 35/95 (36%), Positives = 48/95 (50%), Gaps = 2/95 (2%)
Frame = +1
Query: 162 MYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQL--VRGEPNVSYICS 219
+Y + L Y+HS HRDIK N+LL+ + KL DFG A QL + N + I +
Sbjct: 76 LYYTLKGL*YLHSRRKIHRDIKAGNILLNNEGHA-KLADFGVAGQLTDTMAKRN-TVIGT 249
Query: 220 RYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQ 254
Y+ APE+I Y D+WS G E+ G
Sbjct: 250 PYWMAPEVIQ-EIGYDCVADIWSLGITALEMAEGN 351
>21433
Length = 590
Score = 49.7 bits (117), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 35/95 (36%), Positives = 51/95 (53%)
Frame = +2
Query: 161 YMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSR 220
Y+YQL +L Y H + HRDIKP+NLLL LK+ DFG + + +
Sbjct: 182 YIYQLSSALEYCHYRKVIHRDIKPENLLLG-LKGDLKIADFGWSVHAPSSR-RTTMCGTL 355
Query: 221 YYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQP 255
Y PE++ G T + ++D+WS G + E L+G P
Sbjct: 356 DYLPPEMVEGKT-HDENVDLWSLGVLCYEFLVGTP 457
>14477
Length = 493
Score = 48.9 bits (115), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 50/179 (27%), Positives = 83/179 (46%), Gaps = 9/179 (5%)
Frame = -1
Query: 57 TDTKVIGNGSFGVVYQAKLC--DSGELVAIKKVLQDKRFK-------NRELQIMRKLDHC 107
D +G G+FG V + +C D E+ KVL++ +E ++M+K+DH
Sbjct: 481 MDELKLGAGNFGSVMKG-VCRLDDREIPVAIKVLKNADLDPSVQSELIKEAEVMKKMDHM 305
Query: 108 NIVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFR 167
+IVRL GE + LVL+ + + + + K LP+ + M+Q+ +
Sbjct: 304 HIVRL--IGLCEGET-----MMLVLELAK--LGPLNKFLPKNKH-LPLWNILELMWQVSQ 155
Query: 168 SLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPE 226
+ Y+ + HRD+ +N+LL D K+ DFG +K L R + YY A E
Sbjct: 154 GMEYLEANKFVHRDLAARNILL-CDEHFAKISDFGMSKTLSRE--------NNYYMAQE 5
>00715
Length = 1788
Score = 48.9 bits (115), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 38/119 (31%), Positives = 50/119 (42%), Gaps = 23/119 (19%)
Frame = +1
Query: 164 QLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQL---------------- 207
Q+ R L Y+HS I H D+KP N LL D L++ DFG QL
Sbjct: 262 QMARGLHYLHSINIVHLDLKPANCLLTRDLK-LRIADFGCCHQLTPTGLDMGEREGGMAG 438
Query: 208 -------VRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPG 259
V+G + YRAPEL+ G S DV+S G L ++ Q + G
Sbjct: 439 NELELTPVQGAWKNELAGTLAYRAPELLKGLQPSVRS-DVYSLGITLWQMCTRQGPYEG 612
>04852
Length = 1462
Score = 47.0 bits (110), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 32/97 (32%), Positives = 50/97 (51%), Gaps = 2/97 (2%)
Frame = +1
Query: 161 YMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSR 220
Y +Q+ R + ++ S HRD+ +N+L+ + VLK+ DFG ++ +
Sbjct: 340 YAFQIARGMEFLASRKCIHRDLAARNVLV-TEEHVLKIADFGLSRTGDYYKKRSGGRLPV 516
Query: 221 YYRAPELIFGATDYTSSIDVWSAGCVLAEL--LLGQP 255
+ APE +F YT+ DVWS G VL E+ L G P
Sbjct: 517 KWMAPEALFDMR-YTTKSDVWSFGVVLWEIFSLGGMP 624
>28157
Length = 400
Score = 47.0 bits (110), Expect = 2e-05, Method: Composition-based stats.
Identities = 38/128 (29%), Positives = 62/128 (48%), Gaps = 5/128 (3%)
Frame = +3
Query: 82 VAIKKVL--QDKRFKNRELQIMRKLDHCNIVRLRYFFYSSGEKKDEVYLNLVLDYVPETV 139
VA+K++ Q+K+ +EL+ + ++ H NIV L G +D + LV++Y
Sbjct: 9 VAVKRIESEQEKKSFMQELKQLSRVSHPNIVCL------YGACRDHP-VCLVMEYAEGGS 167
Query: 140 YRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSF---GICHRDIKPQNLLLDPDTAVL 196
H S + + ++ Q + Y+H + HRD+KP NLLL L
Sbjct: 168 LYNVLHGSGPQPQYTAAHAMNWLLQCALGVEYLHGMKPKALIHRDLKPPNLLLIQCGTKL 347
Query: 197 KLCDFGSA 204
K+CDFG+A
Sbjct: 348 KICDFGTA 371
>21808
Length = 1011
Score = 46.2 bits (108), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 44/177 (24%), Positives = 87/177 (49%), Gaps = 4/177 (2%)
Frame = +1
Query: 97 ELQIMRKLDHCNIVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVI 156
E QIM+KL H +++L Y+ + D +++ L ++ + R + +I
Sbjct: 82 EAQIMKKLRHPKLIQL----YAVCTQDDPIFIITEL-MKNGSLLEFLQGKGRVLKLPALI 246
Query: 157 YVKLYMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSY 216
+ Q+ +AY+ S HRD+ +N+L+ D +K+ DFG A+ +++ + +
Sbjct: 247 DIGA---QIACGMAYLESQNYIHRDLAARNILVS-DNNTVKIADFGLAR-VIKEDEYEAR 411
Query: 217 ICSRY---YRAPELIFGATDYTSSIDVWSAGCVLAE-LLLGQPIFPGDSGVDQLVEI 269
+ +R+ + APE +T DVWS G +L E + G+ +PG + + L ++
Sbjct: 412 VGARFPIKWTAPEAA-NYNRFTIKSDVWSFGILLTETVTYGRVPYPGMTNAEVLHQV 579
>11404
Length = 563
Score = 45.4 bits (106), Expect = 5e-05, Method: Compositional matrix adjust.
Identities = 49/162 (30%), Positives = 79/162 (48%), Gaps = 13/162 (8%)
Frame = +1
Query: 41 VATPGQG-PDRPQEVSYTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRE-- 97
+ +PG+ DR Y +IG GSFG V +A E VAIK + K F N+
Sbjct: 112 IISPGEKWADR-----YEIDSLIGKGSFGQVVKAYDHTDNEQVAIKIIKNKKPFLNQAQI 276
Query: 98 ----LQIMRKLDHCN---IVRL-RYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRA 149
L++M + D N IVRL R+F + S +L LV + + +Y + R+ +
Sbjct: 277 EVKLLEMMNRHDTDNKYYIVRLKRHFMFRS-------HLCLVFELLSYNLYDLLRNTNFR 435
Query: 150 KQTLPVIYVKLYMYQLFRSLAYIHS--FGICHRDIKPQNLLL 189
+L + + + QL +L ++ + I H D+KP+N+LL
Sbjct: 436 GVSLNL--TRKFAQQLCTALLFLATPEMSIIHCDLKPENILL 555
>21079
Length = 878
Score = 44.7 bits (104), Expect = 8e-05, Method: Compositional matrix adjust.
Identities = 28/95 (29%), Positives = 52/95 (54%), Gaps = 2/95 (2%)
Frame = +1
Query: 161 YMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTA-VLKLCDFGSAKQLVRGEPNVSYICS 219
++ Q+ + Y+H+ I H D+KP+N+L D + +K+ DFG A+ G+ +
Sbjct: 142 FVRQICSGVGYMHTQSILHLDLKPENVLCVSDNSNQIKIIDFGLARFYKPGDSLQVLFGT 321
Query: 220 RYYRAPELI-FGATDYTSSIDVWSAGCVLAELLLG 253
+ APE++ + ++T+ D+WS G + LL G
Sbjct: 322 PEFIAPEVVNYDEINFTT--DMWSIGVICYILLSG 420
>12672
Length = 773
Score = 43.9 bits (102), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 32/90 (35%), Positives = 46/90 (51%), Gaps = 5/90 (5%)
Frame = +3
Query: 169 LAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGE----PNVS-YICSRYYR 223
+ Y++ G HRDIK N+LLD + K+ DF + GE N S I + Y
Sbjct: 30 IQYLNDNGHVHRDIKTANILLDSEYTA-KVGDFATVVSAPSGEGKTVQNASVVIGTAAYL 206
Query: 224 APELIFGATDYTSSIDVWSAGCVLAELLLG 253
APE I D ++ +D +S G VL E++ G
Sbjct: 207 APEAIH--FDVSTKLDSYSFGVVLLEVITG 290
>16708
Length = 1397
Score = 42.4 bits (98), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 42/158 (26%), Positives = 69/158 (43%), Gaps = 12/158 (7%)
Frame = -1
Query: 60 KVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSS 119
+V+G G FG VY+A+L + E A+K + + L + L R+ FY +
Sbjct: 1385 QVLGKGVFGKVYEARLLSTHEKAALKTSI----LCHHSLDEVEALG-----RIEGGFYLA 1233
Query: 120 GEKKDEVY------LNLVLD-YVPETVYRVARHYSRAKQTLPVIYVKLYMY-----QLFR 167
V +N++L Y + V HY + +P+ + M Q
Sbjct: 1232 QMFGAWVTCLPFPKMNILLHFYEMGPLCNVYAHYK--NKEMPIRWSNPAMVCCIAGQXVC 1059
Query: 168 SLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAK 205
+L +IH G+ H D+K N+L+D KL D+G A+
Sbjct: 1058 ALEHIHELGVVHMDVKADNVLVDAH-GNCKLTDYGIAQ 948
>07291
Length = 833
Score = 40.4 bits (93), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 30/112 (26%), Positives = 51/112 (45%), Gaps = 7/112 (6%)
Frame = +1
Query: 147 SRAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQ 206
++ + L V+ + + Q+ +AY+ + HR++ +N ++ D L+L D+G
Sbjct: 22 AKPSKMLTVVQLLDFGRQIADGMAYLQEVKVVHRNLAARNCIVTED-GRLQLSDYGVTGS 198
Query: 207 LVRGEPNVSYICSRY-------YRAPELIFGATDYTSSIDVWSAGCVLAELL 251
L P Y + APE I ++S DVW+ G VL ELL
Sbjct: 199 LF---PQSYYTADDSPARDLVKWMAPETI-DNFHFSSKSDVWAFGVVLWELL 342
>00638
Length = 1595
Score = 40.0 bits (92), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 15/39 (38%), Positives = 25/39 (64%)
Frame = +2
Query: 146 YSRAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHRDIKP 184
+ + QT ++ Y+Y+L ++L + HS GI HRD+KP
Sbjct: 386 FKQLYQTFTDYDIRFYLYELMKALDFCHSMGIMHRDVKP 502
>13078
Length = 773
Score = 39.7 bits (91), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 32/136 (23%), Positives = 57/136 (41%), Gaps = 8/136 (5%)
Frame = -1
Query: 234 YTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGT-PTREQIREMNPNYTEFK 292
++ DVWS GC++ EL G +F + L + ++LG+ P R + Y F
Sbjct: 746 WSQPCDVWSIGCIMFELYTGYTLFQTHDNKEHLAMMERILGSLPYRMAKKTKKQKY--FY 573
Query: 293 FPQIKAHPWTKDSSGTGHFTSGVRVFR-------PRTPPEAIALCSRLLEYTPTARLTPL 345
++ W + SS + V+ R + L ++L Y + R +
Sbjct: 572 HGRLD---WDEKSSAGRYVRDNVKPLRRYVKDPDNEDHQQLFDLMDKMLSYEVSTRYSLR 402
Query: 346 EACAHSFFDELRDPNV 361
+A H FF +L + +V
Sbjct: 401 QAMRHPFFRKLYEGDV 354
>36481
Length = 806
Score = 39.7 bits (91), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 34/138 (24%), Positives = 60/138 (43%), Gaps = 11/138 (7%)
Frame = +2
Query: 63 GNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNR---ELQIMRKL-------DHCNIVRL 112
G G+FG V Q K G+ +A+K + +++ E+ ++ KL H + L
Sbjct: 389 GEGTFGKVVQCKDLLKGDDIALKIIKNVDKYREAAKLEINVLEKLREKDPHAKHMCVQML 568
Query: 113 RYFFYSSGEKKDEVYLNL-VLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAY 171
+F Y L L V D++ + Y P+ V+ YQL ++ +
Sbjct: 569 DWFDYHGHVCISFHMLGLSVFDFLKDNSY----------GAYPIEQVRHISYQLCYAVNF 718
Query: 172 IHSFGICHRDIKPQNLLL 189
+H + H D+KP+N+L
Sbjct: 719 LHENQLTHTDLKPENILF 772
>16003
Length = 926
Score = 38.9 bits (89), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 19/45 (42%), Positives = 28/45 (62%), Gaps = 2/45 (4%)
Frame = -1
Query: 250 LLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMN--PNYTEFK 292
LL+ P PGD+ +DQL +I +LGTPT + + P+Y +FK
Sbjct: 926 LLIRLPFLPGDTDLDQLGKIFNMLGTPTETEWPAVTSLPDYIQFK 792
>26009
Length = 886
Score = 38.5 bits (88), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 18/36 (50%), Positives = 24/36 (66%), Gaps = 1/36 (2%)
Frame = +3
Query: 158 VKLYMYQLFRSLAYIHSFGICHRDIKPQN-LLLDPD 192
K M QL +L ++HS + HRDIKP+N L+L PD
Sbjct: 717 AKSVMKQLVSALDFMHSKQLVHRDIKPENVLILTPD 824
>01106
Length = 878
Score = 37.7 bits (86), Expect = 0.009, Method: Compositional matrix adjust.
Identities = 18/48 (37%), Positives = 30/48 (62%), Gaps = 1/48 (2%)
Frame = +3
Query: 151 QTLPVIYVKLYMYQLFRSLAYIHS-FGICHRDIKPQNLLLDPDTAVLK 197
Q +P+ VKL + Q+ L+Y+H+ I H DIKP+N+L+ D ++
Sbjct: 630 QGIPIHNVKLIIRQVLEGLSYMHAKCRIIHTDIKPENILICVDETYIR 773
>21800
Length = 855
Score = 37.7 bits (86), Expect = 0.010, Method: Compositional matrix adjust.
Identities = 19/43 (44%), Positives = 27/43 (62%), Gaps = 1/43 (2%)
Frame = +2
Query: 151 QTLPVIYVKLYMYQLFRSLAYIHS-FGICHRDIKPQNLLLDPD 192
Q +PV VKL + Q+ L Y+H+ I H DIKP+N+L+ D
Sbjct: 617 QGIPVHNVKLIIRQVLEGLNYLHAKCNIIHTDIKPENILICVD 745
>25019
Length = 730
Score = 37.7 bits (86), Expect = 0.010, Method: Compositional matrix adjust.
Identities = 24/61 (39%), Positives = 31/61 (50%), Gaps = 1/61 (1%)
Frame = +3
Query: 185 QNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRY-YRAPELIFGATDYTSSIDVWSA 243
+N+LLD D V KL DFG K+ + G C Y APE I T + ++D WS
Sbjct: 261 ENVLLDKDGHV-KLTDFGLCKEAITGTRVTHTFCGTIEYMAPE-ILTRTGHGKAVDWWSL 434
Query: 244 G 244
G
Sbjct: 435 G 437
>29360
Length = 363
Score = 36.2 bits (82), Expect = 0.023, Method: Composition-based stats.
Identities = 29/120 (24%), Positives = 57/120 (47%), Gaps = 8/120 (6%)
Frame = +3
Query: 78 SGELVAIKKVLQDKRFKNR---ELQIMRKL-----DHCNIVRLRYFFYSSGEKKDEVYLN 129
+ E+VAIK + + + E+ I+++L D N VR F + + +
Sbjct: 24 TSEIVAIKILKNHPSYARQGQIEVSILQRLSQESADDYNFVRAFECF------QHKNHTC 185
Query: 130 LVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHRDIKPQNLLL 189
LV + + + +Y + Q LP+ Y++ Q+ +L + G+ H D+KP+N++L
Sbjct: 186 LVFEMLEQNLYDFLKQ--NKFQPLPLKYIRPITQQVLTALRKLKQLGLIHADLKPENIML 359
>20152
Length = 445
Score = 36.2 bits (82), Expect = 0.024, Method: Compositional matrix adjust.
Identities = 24/93 (25%), Positives = 40/93 (43%), Gaps = 9/93 (9%)
Frame = +1
Query: 225 PELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKV-------LGTPT 277
PE++ G + ++DVWS G +L L++G+ F + + L I+ +
Sbjct: 1 PEILLGDSYDAPAVDVWSLGVILYMLVVGEAPFQEANDSETLTMIMDCRYQIPPHISHKC 180
Query: 278 REQIREM--NPNYTEFKFPQIKAHPWTKDSSGT 308
++ I +M P I AHPW D T
Sbjct: 181 QDLIEKMLQREPVDRASLPHILAHPWLNDGDLT 279
>02638
Length = 1490
Score = 35.0 bits (79), Expect = 0.063, Method: Compositional matrix adjust.
Identities = 17/51 (33%), Positives = 28/51 (54%)
Frame = +1
Query: 222 YRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKV 272
+ APE++ G + Y + DVWS GCV+ E+ +P + + L I K+
Sbjct: 34 FMAPEVLRGES-YGRACDVWSVGCVMIEMCTCRPPWNSHDISNHLALIFKI 183
>00486
Length = 797
Score = 33.9 bits (76), Expect = 0.12, Method: Compositional matrix adjust.
Identities = 16/50 (32%), Positives = 28/50 (56%)
Frame = -2
Query: 222 YRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIK 271
Y APE I T + ++D WS G ++ ++L G P F ++ + +I+K
Sbjct: 760 YMAPE-ILTRTGHGKAVDWWSLGALMYDMLTGSPPFTAENRKKTIDKILK 614
>37602
Length = 804
Score = 33.1 bits (74), Expect = 0.22, Method: Compositional matrix adjust.
Identities = 17/38 (44%), Positives = 22/38 (57%)
Frame = -1
Query: 164 QLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDF 201
+ + L Y+H G HRDIK N+LL + V KL DF
Sbjct: 195 ETLKGLHYLHRRGKMHRDIKGANILLTEEGDV-KLADF 85
>18481
Length = 437
Score = 32.0 bits (71), Expect = 0.44, Method: Compositional matrix adjust.
Identities = 18/45 (40%), Positives = 23/45 (51%), Gaps = 2/45 (4%)
Frame = -1
Query: 164 QLFRSLAYIHSFGICHRDIKPQNLL--LDPDTAVLKLCDFGSAKQ 206
QL L +IH HRD+KP N L L L + DFG +K+
Sbjct: 173 QLLSRLEFIHQKCFIHRDLKPDNFLMGLGRHCHRLYIIDFGLSKR 39
>35032
Length = 465
Score = 31.6 bits (70), Expect = 0.62, Method: Compositional matrix adjust.
Identities = 14/25 (56%), Positives = 15/25 (60%)
Frame = +3
Query: 329 LCSRLLEYTPTARLTPLEACAHSFF 353
L RLL Y P+ RLTP A AH F
Sbjct: 150 LVKRLLNYDPSKRLTPXXALAHPFL 224
>38560
Length = 479
Score = 30.8 bits (68), Expect = 1.0, Method: Compositional matrix adjust.
Identities = 16/32 (50%), Positives = 18/32 (56%)
Frame = -3
Query: 222 YRAPELIFGATDYTSSIDVWSAGCVLAELLLG 253
Y APELI G S D+WS G +L LL G
Sbjct: 387 YAAPELISGLEYLGSEADIWSMGVLLYALLCG 292
>19248
Length = 973
Score = 30.0 bits (66), Expect = 1.8, Method: Compositional matrix adjust.
Identities = 20/88 (22%), Positives = 41/88 (46%)
Frame = -3
Query: 6 RTTSFAESCKPVQQPSAFGSMKVSRDKDGSKVTTVVATPGQGPDRPQEVSYTDTKVIGNG 65
+T++ A PV+ P+ +GSM S+D G P+ P E S++D + G
Sbjct: 497 QTSAHAPQHYPVEDPAGYGSMHASKD-------------GNFPELPLESSHSDERGPCRG 357
Query: 66 SFGVVYQAKLCDSGELVAIKKVLQDKRF 93
S ++ + +L A+ ++ +++
Sbjct: 356 SHLLMMETHT**WRKLGAVSTIIWPRKY 273
>32357
Length = 625
Score = 30.0 bits (66), Expect = 1.8, Method: Compositional matrix adjust.
Identities = 16/37 (43%), Positives = 22/37 (59%)
Frame = -2
Query: 56 YTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKR 92
Y K IG+GSFG +Y SGE VA+K L++ +
Sbjct: 432 YRLMKKIGSGSFGEIYLGVHNTSGEEVAVKLELKNAK 322
>24241
Length = 413
Score = 30.0 bits (66), Expect = 1.9, Method: Composition-based stats.
Identities = 17/55 (30%), Positives = 30/55 (54%), Gaps = 10/55 (18%)
Frame = -2
Query: 62 IGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKN----------RELQIMRKLDH 106
IG G++GVVY+ + +G +A+KK+ R + RE+ ++R+L H
Sbjct: 319 IGEGTYGVVYKCRHRATGRKLAMKKI----RLRGSEDGVPSSAIREIAMLRELRH 167
>19149
Length = 454
Score = 28.5 bits (62), Expect = 5.1, Method: Compositional matrix adjust.
Identities = 12/22 (54%), Positives = 15/22 (68%)
Frame = -3
Query: 319 RPRTPPEAIALCSRLLEYTPTA 340
P+ P A+ALCSRLL TP +
Sbjct: 77 EPKDPSSALALCSRLLVLTPNS 12
>32957
Length = 645
Score = 28.1 bits (61), Expect = 6.4, Method: Compositional matrix adjust.
Identities = 14/40 (35%), Positives = 21/40 (52%)
Frame = +3
Query: 215 SYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQ 254
++ +R Y APE + +Y +D W G +L ELL Q
Sbjct: 42 TFCGTREYMAPE-VHERKEYGKEVDWWGLGILLHELLAAQ 158
>26052
Length = 562
Score = 28.1 bits (61), Expect = 7.7, Method: Compositional matrix adjust.
Identities = 13/32 (40%), Positives = 20/32 (62%)
Frame = -1
Query: 56 YTDTKVIGNGSFGVVYQAKLCDSGELVAIKKV 87
Y K++G GSFG V + D+GE +A+K +
Sbjct: 385 YLFXKLLGVGSFGKVMALQHKDTGETLAVKNI 290
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000331829 | hsapiens_gene_ensembl | Paxillin.
[Source:Uniprot/SWISSPROT;Acc:P49023]
(233 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
11928 293 5e-80
09680 118 2e-27
07437 102 1e-22
14307 85 3e-17
05726 75 2e-14
34420 44 5e-05
26762 43 1e-04
05103 37 0.008
30169 31 0.43
07747 28 2.4
17933 28 3.0
04349 27 9.8
>11928
Length = 1623
Score = 293 bits (749), Expect = 5e-80, Method: Compositional matrix adjust.
Identities = 131/185 (70%), Positives = 152/185 (82%)
Frame = -2
Query: 1 MGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPILDKVVTAL 60
+G+TWH EHFVC HC++ +G+ NF+ERD YCE DYHNLF+PRC YCNGPI+DK +TAL
Sbjct: 1553 LGRTWHVEHFVCAHCEQPLGTSNFYERDSVAYCEVDYHNLFAPRCAYCNGPIVDKCITAL 1374
Query: 61 DRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAILENYISALN 120
++ WHPEHFFCAQCG FG E FHEK+GKAYCR DYF MFAPKCGGC I+ENYISALN
Sbjct: 1373 EKMWHPEHFFCAQCGRQFGDEDFHEKNGKAYCRDDYFQMFAPKCGGCGMPIMENYISALN 1194
Query: 121 TLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPITGRCITAMAK 180
WHP+CF C EC PF GSF++HDG PYCE HYH ++GSLC+ CQKPITGRCITAM K
Sbjct: 1193 RQWHPQCFCCWECQAPFGTGSFYDHDGLPYCETHYHAKKGSLCASCQKPITGRCITAMFK 1014
Query: 181 KFHPD 185
KFHP+
Sbjct: 1013 KFHPE 999
Score = 125 bits (313), Expect = 2e-29, Method: Compositional matrix adjust.
Identities = 59/141 (41%), Positives = 81/141 (57%)
Frame = -2
Query: 45 CYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKC 104
C CN PI+ +V+ AL RTWH EHF CA C G F+E+D AYC DY ++FAP+C
Sbjct: 1598 CAACNKPIVGQVIAALGRTWHVEHFVCAHCEQPLGTSNFYERDSVAYCEVDYHNLFAPRC 1419
Query: 105 GGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCS 164
C I++ I+AL +WHPE F C +C F + F E +G+ YC Y + C
Sbjct: 1418 AYCNGPIVDKCITALEKMWHPEHFFCAQCGRQFGDEDFHEKNGKAYCRDDYFQMFAPKCG 1239
Query: 165 GCQKPITGRCITAMAKKFHPD 185
GC PI I+A+ +++HP
Sbjct: 1238 GCGMPIMENYISALNRQWHPQ 1176
Score = 110 bits (274), Expect(2) = 1e-26, Method: Compositional matrix adjust.
Identities = 51/131 (38%), Positives = 73/131 (55%)
Frame = -2
Query: 1 MGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPILDKVVTAL 60
+ K WHPEHF C C + G +F E++G+ YC DY +F+P+C C PI++ ++AL
Sbjct: 1376 LEKMWHPEHFFCAQCGRQFGDEDFHEKNGKAYCRDDYFQMFAPKCGGCGMPIMENYISAL 1197
Query: 61 DRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAILENYISALN 120
+R WHP+ F C +C A FG F++ DG YC Y C C + I I+A+
Sbjct: 1196 NRQWHPQCFCCWECQAPFGTGSFYDHDGLPYCETHYHAKKGSLCASCQKPITGRCITAMF 1017
Query: 121 TLWHPECFVCR 131
+HPE F R
Sbjct: 1016 KKFHPEHFCLR 984
Score = 26.6 bits (57), Expect(2) = 1e-26, Method: Compositional matrix adjust.
Identities = 10/24 (41%), Positives = 13/24 (54%)
Frame = -3
Query: 128 FVCRECFTPFVNGSFFEHDGQPYC 151
FVC C G+F E + +PYC
Sbjct: 994 FVCAFCIKQLNKGTFKEQNDKPYC 923
Score = 28.1 bits (61), Expect = 3.0, Method: Compositional matrix adjust.
Identities = 11/40 (27%), Positives = 21/40 (52%)
Frame = -3
Query: 2 GKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLF 41
+++ FVC C +++ F E++ +PYC + LF
Sbjct: 1018 SRSFTRSIFVCAFCIKQLNKGTFKEQNDKPYCHPCFVKLF 899
>09680
Length = 878
Score = 118 bits (296), Expect = 2e-27, Method: Compositional matrix adjust.
Identities = 56/152 (36%), Positives = 78/152 (51%), Gaps = 1/152 (0%)
Frame = -2
Query: 1 MGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPILDKVVTAL 60
+GK +HPEHF+C C ++I F + G+P C Y ++ C C PI ++A+
Sbjct: 670 LGKNYHPEHFLCRDCDKQIKDDIFNIQQGEPVCNACYLERYTSTCAGCKEPIHGTTISAM 491
Query: 61 DRTWHPEHFFC-AQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAILENYISAL 119
WH F C C F E++GKAYCR+DY D+FA +C C + I EN I A+
Sbjct: 490 GNNWHEHCFVCDGACKQPLKDSSFFEREGKAYCRQDYEDLFAVRCAKCEKPITENAIVAM 311
Query: 120 NTLWHPECFVCRECFTPFVNGSFFEHDGQPYC 151
N WH +CF C C P +F +P C
Sbjct: 310 NAKWHSDCFCCNRCDNPIKTKTFTIEGDKPIC 215
Score = 108 bits (269), Expect = 3e-24, Method: Compositional matrix adjust.
Identities = 54/143 (37%), Positives = 73/143 (51%), Gaps = 1/143 (0%)
Frame = -2
Query: 44 RCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPK 103
+C+ CN I +VV AL + +HPEHF C C + F+ + G+ C Y + +
Sbjct: 718 QCHKCNEAITSRVVFALGKNYHPEHFLCRDCDKQIKDDIFNIQQGEPVCNACYLERYTST 539
Query: 104 CGGCARAILENYISALNTLWHPECFVCR-ECFTPFVNGSFFEHDGQPYCEVHYHERRGSL 162
C GC I ISA+ WH CFVC C P + SFFE +G+ YC Y +
Sbjct: 538 CAGCKEPIHGTTISAMGNNWHEHCFVCDGACKQPLKDSSFFEREGKAYCRQDYEDLFAVR 359
Query: 163 CSGCQKPITGRCITAMAKKFHPD 185
C+ C+KPIT I AM K+H D
Sbjct: 358 CAKCEKPITENAIVAMNAKWHSD 290
>07437
Length = 951
Score = 102 bits (254), Expect = 1e-22, Method: Compositional matrix adjust.
Identities = 60/188 (31%), Positives = 86/188 (45%), Gaps = 6/188 (3%)
Frame = +3
Query: 1 MGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYC-----EKDYHNLFSPRCYYCNGPI-LD 54
M WHP+ F+C C + F + G+ C ++ C+ C+ I ++
Sbjct: 12 MNSAWHPQCFLCQLCGTCMADSGFVKNAGRALCRECNAKEKARGTGKYVCHKCHDVIEMN 191
Query: 55 KVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAILEN 114
+ +HP HF C CG E EKD + YC + + M P CG C R I E
Sbjct: 192 GHIKFRGEAYHPYHFNCHSCGVELNTEA-REKDSELYCLRCHDKMGIPICGACRRPIEER 368
Query: 115 YISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPITGRC 174
+ AL WH E FVC +C PF+ +E G YCE+HYH+ G++C C I G
Sbjct: 369 VVHALGKAWHVEHFVCAKCEKPFLGTRHYEKKGLAYCEIHYHQLFGNICFVCNNIINGDV 548
Query: 175 ITAMAKKF 182
+A K +
Sbjct: 549 FSAFNKAW 572
Score = 90.5 bits (223), Expect = 5e-19, Method: Compositional matrix adjust.
Identities = 57/162 (35%), Positives = 77/162 (47%), Gaps = 1/162 (0%)
Frame = +3
Query: 2 GKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPILDKVVTALD 61
G+ +HP HF C C E+ + E+D + YC + + + P C C PI ++VV AL
Sbjct: 210 GEAYHPYHFNCHSCGVELNTEAR-EKDSELYCLRCHDKMGIPICGACRRPIEERVVHALG 386
Query: 62 RTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAILENYISALNT 121
+ WH EHF CA+C F +EK G AYC Y +F C C I + SA N
Sbjct: 387 KAWHVEHFVCAKCEKPFLGTRHYEKKGLAYCEIHYHQLFGNICFVCNNIINGDVFSAFNK 566
Query: 122 LWHPECFVCRECFTPFVNGS-FFEHDGQPYCEVHYHERRGSL 162
W F C C + FFE D +P C+ Y + G L
Sbjct: 567 AWCVHHFACSICDRKMSQKTKFFEFDQKPVCKNCYDKFPGEL 692
Score = 70.1 bits (170), Expect = 7e-13, Method: Compositional matrix adjust.
Identities = 38/101 (37%), Positives = 51/101 (50%), Gaps = 1/101 (0%)
Frame = +3
Query: 1 MGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPILDKVVTAL 60
+GK WH EHFVC C++ +E+ G YCE YH LF C+ CN I V +A
Sbjct: 381 LGKAWHVEHFVCAKCEKPFLGTRHYEKKGLAYCEIHYHQLFGNICFVCNNIINGDVFSAF 560
Query: 61 DRTWHPEHFFCAQCGAFFGPE-GFHEKDGKAYCRKDYFDMF 100
++ W HF C+ C + F E D K C K+ +D F
Sbjct: 561 NKAWCVHHFACSICDRKMSQKTKFFEFDQKPVC-KNCYDKF 680
Score = 56.2 bits (134), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 43/160 (26%), Positives = 67/160 (41%), Gaps = 9/160 (5%)
Frame = +3
Query: 57 VTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAP-----KCGGCARAI 111
+ A++ WHP+ F C CG GF + G+A CR+ A C C I
Sbjct: 3 IKAMNSAWHPQCFLCQLCGTCMADSGFVKNAGRALCRECNAKEKARGTGKYVCHKCHDVI 182
Query: 112 -LENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGS-LCSGCQKP 169
+ +I +HP F C C +N E D + YC + H++ G +C C++P
Sbjct: 183 EMNGHIKFRGEAYHPYHFNCHSCGVE-LNTEAREKDSELYC-LRCHDKMGIPICGACRRP 356
Query: 170 ITGRCITAMAKKFHPD--PCTSPRTGLASTPHWSHLFLIF 207
I R + A+ K +H + C T H+ L +
Sbjct: 357 IEERVVHALGKAWHVEHFVCAKCEKPFLGTRHYEKKGLAY 476
>14307
Length = 816
Score = 84.7 bits (208), Expect = 3e-17, Method: Compositional matrix adjust.
Identities = 51/174 (29%), Positives = 77/174 (44%), Gaps = 3/174 (1%)
Frame = +2
Query: 2 GKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPILD-KVVTAL 60
G WHP FVC+ C+E + + + D YC++ Y L PRC C+ I + A+
Sbjct: 245 GTVWHPACFVCSTCEELLVDLVYCQHDKHLYCQRHYAELIRPRCPGCDELIFSGEYTKAM 424
Query: 61 DRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAILENY--ISA 118
+ +H +H C QC + +D +C Y +FA KC C + I +Y +S
Sbjct: 425 EECYHKDHLACWQCDKQLVSCRYIMRDDHPHCVPCYQALFANKCEDCDKPIGPDYKDLSY 604
Query: 119 LNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPITG 172
+ WH CF C C V+ F + + +C Y + C GC P G
Sbjct: 605 KDKHWHEFCFKCTMCDKSLVDQPFAPKNEKIFCSECYDNSFAARCDGCGNPFKG 766
Score = 50.8 bits (120), Expect = 5e-07, Method: Compositional matrix adjust.
Identities = 26/66 (39%), Positives = 35/66 (53%), Gaps = 1/66 (1%)
Frame = +2
Query: 121 TLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPI-TGRCITAMA 179
T+WHP CFVC C V+ + +HD YC+ HY E C GC + I +G AM
Sbjct: 248 TVWHPACFVCSTCEELLVDLVYCQHDKHLYCQRHYAELIRPRCPGCDELIFSGEYTKAME 427
Query: 180 KKFHPD 185
+ +H D
Sbjct: 428 ECYHKD 445
>05726
Length = 733
Score = 75.1 bits (183), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 42/135 (31%), Positives = 61/135 (45%), Gaps = 4/135 (2%)
Frame = +1
Query: 21 SRNFFERDGQPYCEKDYHNLFSPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGP 80
+++F RD + C Y N ++ RC+ C+ I ++ + WH E F C C
Sbjct: 1 NKSFIPRDDRVICVPCYENNYAQRCFKCSQVINKGGISYKNTPWHRECFTCTHCDKMLAG 180
Query: 81 EGFHEKDGKAYCRKDYFDMFAPKCGGCARAIL----ENYISALNTLWHPECFVCRECFTP 136
E F KD + YC + D+FA KC C +AI +IS WH +CF C +C
Sbjct: 181 EKFTSKDDQPYCGDCFGDLFAKKCCRCQKAITGIGGTKFISFEERHWHSDCFTCFKCQAS 360
Query: 137 FVNGSFFEHDGQPYC 151
V F +D C
Sbjct: 361 MVGRGFLMNDDDIVC 405
Score = 60.1 bits (144), Expect = 8e-10, Method: Compositional matrix adjust.
Identities = 31/92 (33%), Positives = 43/92 (46%), Gaps = 4/92 (4%)
Frame = +1
Query: 5 WHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPIL----DKVVTAL 60
WH E F CTHC + + F +D QPYC + +LF+ +C C I K ++
Sbjct: 130 WHRECFTCTHCDKMLAGEKFTSKDDQPYCGDCFGDLFAKKCCRCQKAITGIGGTKFISFE 309
Query: 61 DRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYC 92
+R WH + F C +C A GF D C
Sbjct: 310 ERHWHSDCFTCFKCQASMVGRGFLMNDDDIVC 405
Score = 58.2 bits (139), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 32/92 (34%), Positives = 43/92 (46%)
Frame = +1
Query: 81 EGFHEKDGKAYCRKDYFDMFAPKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNG 140
+ F +D + C Y + +A +C C++ I + IS NT WH ECF C C
Sbjct: 4 KSFIPRDDRVICVPCYENNYAQRCFKCSQVINKGGISYKNTPWHRECFTCTHCDKMLAGE 183
Query: 141 SFFEHDGQPYCEVHYHERRGSLCSGCQKPITG 172
F D QPYC + + C CQK ITG
Sbjct: 184 KFTSKDDQPYCGDCFGDLFAKKCCRCQKAITG 279
>34420
Length = 719
Score = 43.9 bits (102), Expect = 5e-05, Method: Compositional matrix adjust.
Identities = 24/74 (32%), Positives = 34/74 (45%), Gaps = 4/74 (5%)
Frame = +2
Query: 23 NFFERDGQPYCEKDYHNLFSPRCYYCNGPIL----DKVVTALDRTWHPEHFFCAQCGAFF 78
F +D QPYC + LF+ RC C PI K ++ +R WH + F C +C A
Sbjct: 5 KFTSKDEQPYCGDCFGELFAKRCIRCTQPITGIGGTKFISFEERHWHSDCFVCYRCNASM 184
Query: 79 GPEGFHEKDGKAYC 92
GF + + C
Sbjct: 185VGRGFLMQGEEILC 226
Score = 39.7 bits (91), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 23/75 (30%), Positives = 32/75 (42%), Gaps = 4/75 (5%)
Frame = +2
Query: 81 EGFHEKDGKAYCRKDYFDMFAPKCGGCARAIL----ENYISALNTLWHPECFVCRECFTP 136
E F KD + YC + ++FA +C C + I +IS WH +CFVC C
Sbjct: 2 EKFTSKDEQPYCGDCFGELFAKRCIRCTQPITGIGGTKFISFEERHWHSDCFVCYRCNAS 181
Query: 137 FVNGSFFEHDGQPYC 151
V F + C
Sbjct: 182 MVGRGFLMQGEEILC 226
>26762
Length = 399
Score = 43.1 bits (100), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 23/66 (34%), Positives = 32/66 (48%), Gaps = 4/66 (6%)
Frame = +1
Query: 22 RNFFERDGQPYCEKDYHNLFSPRCYYCNGPIL----DKVVTALDRTWHPEHFFCAQCGAF 77
+ F RD +PYC + LF+ RC C PI + ++ +R WH + F CA C A
Sbjct: 1 QRFTSRDEKPYCAECLGELFAKRCTSCVKPITGIGGTRFISFEERHWHHDCFVCASCKAS 180
Query: 78 FGPEGF 83
GF
Sbjct: 181LVGRGF 198
Score = 38.9 bits (89), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 21/65 (32%), Positives = 29/65 (44%), Gaps = 4/65 (6%)
Frame = +1
Query: 83 FHEKDGKAYCRKDYFDMFAPKCGGCARAIL----ENYISALNTLWHPECFVCRECFTPFV 138
F +D K YC + ++FA +C C + I +IS WH +CFVC C V
Sbjct: 7 FTSRDEKPYCAECLGELFAKRCTSCVKPITGIGGTRFISFEERHWHHDCFVCASCKASLV 186
Query: 139 NGSFF 143
F
Sbjct: 187 GRGFI 201
Score = 26.9 bits (58), Expect = 6.2, Method: Compositional matrix adjust.
Identities = 20/60 (33%), Positives = 26/60 (43%), Gaps = 6/60 (10%)
Frame = +1
Query: 142 FFEHDGQPYCEVHYHERRGSLCSGCQKPITG----RCITAMAKKFHPD--PCTSPRTGLA 195
F D +PYC E C+ C KPITG R I+ + +H D C S + L
Sbjct: 7 FTSRDEKPYCAECLGELFAKRCTSCVKPITGIGGTRFISFEERHWHHDCFVCASCKASLV 186
>05103
Length = 1504
Score = 36.6 bits (83), Expect = 0.008, Method: Compositional matrix adjust.
Identities = 17/56 (30%), Positives = 23/56 (41%)
Frame = +2
Query: 103 KCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHER 158
+CGGC + A +H CF C C FF D + YCE H ++
Sbjct: 641 RCGGCDMLATGVIVKANGVPYHVACFKCESCSMNLKQKGFFVVDDKLYCETHARQK 808
>30169
Length = 426
Score = 30.8 bits (68), Expect = 0.43, Method: Compositional matrix adjust.
Identities = 14/44 (31%), Positives = 21/44 (47%)
Frame = -1
Query: 1 MGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPR 44
MGK +H F CT C++ + S + YC+ Y F P+
Sbjct: 357 MGKVYHKACFKCTSCRKILDSTLLTQHQDNIYCKACYGKNFGPK 226
>07747
Length = 488
Score = 28.5 bits (62), Expect = 2.4, Method: Compositional matrix adjust.
Identities = 11/46 (23%), Positives = 19/46 (41%)
Frame = +1
Query: 114 NYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERR 159
N + +N W +C C + G+F +D + E+ H R
Sbjct: 349 NISAVINNAWMTDCLAIIRCLFQVLLGTFSFYDNVIHMEIKKHNRN 486
>17933
Length = 842
Score = 28.1 bits (61), Expect = 3.0, Method: Compositional matrix adjust.
Identities = 13/33 (39%), Positives = 21/33 (63%)
Frame = +1
Query: 107 CARAILENYISALNTLWHPECFVCRECFTPFVN 139
C+ +++E + NT++ CFV +CFT FVN
Sbjct: 613 CSNSLVEL*MFGYNTIFFLSCFVN*KCFTLFVN 711
>04349
Length = 1161
Score = 26.6 bits (57), Expect = 9.8, Method: Compositional matrix adjust.
Identities = 14/56 (25%), Positives = 21/56 (37%), Gaps = 1/56 (1%)
Frame = +3
Query: 103 KCGGCARAILE-NYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHE 157
KCG C + + I +H CF C C +F + +C HY +
Sbjct: 228 KCGACHKTVYAMEKIEIEKNAYHKSCFRCSHCHCVLTPKTFAINKNVMFCTNHYKQ 395
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000350692 | hsapiens_gene_ensembl | Cytoplasmic
dynein 1 intermediate chain 2 (Dynein intermediate chain 2, cytosolic)
(DH IC-2) (Cytoplasmic dynein intermediate chain 2).
[Source:Uniprot/SWISSPROT;Acc:Q13409]
(605 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
20271 294 6e-80
14105 168 5e-42
12841 112 5e-25
07741 55 9e-08
20662 53 3e-07
08355 47 3e-05
03387 46 4e-05
13278 43 3e-04
02960 41 0.001
27475 34 0.14
05393 34 0.15
01598 34 0.22
00432 32 0.60
27465 32 0.90
01768 31 1.1
06996 30 2.0
26107 30 2.2
37180 30 2.3
00561 30 2.7
12140 29 4.3
01805 29 5.6
03395 29 6.4
30429 28 7.4
>20271
Length = 567
Score = 294 bits (753), Expect = 6e-80, Method: Compositional matrix adjust.
Identities = 137/189 (72%), Positives = 157/189 (83%)
Frame = -1
Query: 349 HPVYCVNVVGTQNAHNLISISTDGKICSWSLDMLSHPQDSMELVHKQSKAVAVTSMSFPV 408
HPVYC+ VVGTQNAHNLIS+S DGK+CSWSLDMLS PQDSMEL HKQSK+VA T SF
Sbjct: 567 HPVYCITVVGTQNAHNLISVSNDGKLCSWSLDMLSQPQDSMELQHKQSKSVAATCFSFLS 388
Query: 409 GDVNNFVVGSEEGSVYTACRHGSKAGISEMFEGHQGPITGIHCHAAVGAVDFSHLFVTSS 468
GD NNF+VGSEE VY+A RHGSKAGI+E +EGHQGPIT I H A G +DFS F+T+S
Sbjct: 387 GDANNFIVGSEECLVYSASRHGSKAGINEAYEGHQGPITAIDTHHAAGQIDFSPFFLTAS 208
Query: 469 FDWTVKLWTTKNNKPLYSFEDNADYVYDVMWSPTHPALFACVDGMGRLDLWNLNNDTEVP 528
FDWTVKLW K K + SFEDN+DYV DV WSPT+PALF+CVD MGRLDLW+LN++TEVP
Sbjct: 207 FDWTVKLWNIKEQKYVCSFEDNSDYVSDVQWSPTNPALFSCVDIMGRLDLWHLNHETEVP 28
Query: 529 TASISVEGN 537
TAS+ V+GN
Sbjct: 27 TASVVVDGN 1
>14105
Length = 429
Score = 168 bits (426), Expect = 5e-42, Method: Compositional matrix adjust.
Identities = 75/111 (67%), Positives = 87/111 (78%)
Frame = +3
Query: 475 LWTTKNNKPLYSFEDNADYVYDVMWSPTHPALFACVDGMGRLDLWNLNNDTEVPTASISV 534
LW+ K+ KPLYSFEDN+DYV DV WSP HPALFA VDG GRLDLWNLN DTEVPTASI V
Sbjct: 3 LWSLKDTKPLYSFEDNSDYVMDVAWSPVHPALFAAVDGSGRLDLWNLNQDTEVPTASIVV 182
Query: 535 EGNPALNRVRWTHSGREIAVGDSEGQIVIYDVGEQIAVPRNDEWARFGRTL 585
+G PALNRV WT SG + +GD G++ +YDV E +A+P DEW+RF TL
Sbjct: 183 DGAPALNRVSWTPSGLHVTIGDESGKLYVYDVAEHLALPTRDEWSRFNATL 335
>12841
Length = 1364
Score = 112 bits (279), Expect = 5e-25, Method: Compositional matrix adjust.
Identities = 80/307 (26%), Positives = 133/307 (43%), Gaps = 22/307 (7%)
Frame = +1
Query: 259 PELLVASYNNNEDAPHEPDGVALVWNMKYKKTTPEYVFHCQSAVMSATFAKFHPNLVVGG 318
P+L+ Y D ++ G+ W++K PE V+ V S F+ + N++ G
Sbjct: 439 PDLVAVGYGQF-DFTNQKSGLICCWSLK-NPEYPERVYTSTHGVTSLDFSVANANILAAG 612
Query: 319 TYSGQIVLWDNRSNKRTPVQRTPLSAAAHTHPVYCVNVV------GTQNAHNLISISTDG 372
Y G + +++ RS P+ + H PV+ + + G + A LISISTDG
Sbjct: 613 YYDGGVAIYNVRSTSDEPILDNQETHGKHLGPVWQIQWIEKERGSGEERAEVLISISTDG 792
Query: 373 KICSWSLDMLSHPQDSMELVH---------KQSKAVAVTS-------MSFPVGDVNNFVV 416
++ WS+ + M L ++ K A S F D+N ++
Sbjct: 793 RVTQWSIRKGFESNNIMRLKKLPTRMAGKAREKKGEAFISRHAGGLCFDFHSRDLNVYLA 972
Query: 417 GSEEGSVYTACRHGSKAGISEMFEGHQGPITGIHCHAAVGAVDFSHLFVTSSFDWTVKLW 476
G+EEG ++ C E + GH P+ I V S +F++ S DW+++LW
Sbjct: 973 GTEEGYIH-KCSCSYNEQYLETYSGHTAPVYHIRWSPFV-----SDIFLSCSADWSIRLW 1134
Query: 477 TTKNNKPLYSFEDNADYVYDVMWSPTHPALFACVDGMGRLDLWNLNNDTEVPTASISVEG 536
P+ +F + V+DV WSP +FACV G +++W+L T +I+
Sbjct: 1135HQDRTTPILTFHSSTKTVHDVCWSPRSSTVFACVH-EGAVEVWDLAQSTLDAVITITPTS 1311
Query: 537 NPALNRV 543
L V
Sbjct: 1312GAKLTSV 1332
>07741
Length = 2119
Score = 55.1 bits (131), Expect = 9e-08, Method: Compositional matrix adjust.
Identities = 43/165 (26%), Positives = 76/165 (46%), Gaps = 17/165 (10%)
Frame = +1
Query: 414 FVVGSEEGSVYTACRHGSKAGISEMFEGHQGPITGIHCHAAVGAVDFSH----LFVTSSF 469
F+VG+EEG V+ C + + + H + AV V ++H ++ T S
Sbjct: 157 FLVGTEEGKVH-VCSKAYTSHFIDTLDSH---------NMAVYKVAWNHYHPKIYATCSA 306
Query: 470 DWTVKLWT-----------TKNNKPLYSFEDNADYVYDVMWSPTHPALFACVDGMGRLDL 518
DW VK+W + + KPL+SF+ N + V DV W+P +FA V G++ +
Sbjct: 307 DWNVKIWENGGKPTDTGXDSLSRKPLFSFDLN-NSVGDVAWAPYSSTVFAAVTADGKVCV 483
Query: 519 WNLNNDTEVPTAS--ISVEGNPALNRVRWTHSGREIAVGDSEGQI 561
++L+ + P ++ + L + + S + VGD G +
Sbjct: 484 YDLSVNKYEPLCEQMVAQKKKTKLTHIEFNPSYPILIVGDDRGNV 618
Score = 30.0 bits (66), Expect = 3.0, Method: Compositional matrix adjust.
Identities = 20/81 (24%), Positives = 37/81 (45%), Gaps = 8/81 (9%)
Frame = +1
Query: 494 VYDVMWSPTHPALFACVDGMGRLDLW-NLNNDTEVPTASI------SVEGNPALNRVRWT 546
VY V W+ HP ++A + +W N T+ S+ S + N ++ V W
Sbjct: 250 VYKVAWNHYHPKIYATCSADWNVKIWENGGKPTDTGXDSLSRKPLFSFDLNNSVGDVAWA 429
Query: 547 -HSGREIAVGDSEGQIVIYDV 566
+S A ++G++ +YD+
Sbjct: 430 PYSSTVFAAVTADGKVCVYDL 492
>20662
Length = 1220
Score = 53.1 bits (126), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 39/131 (29%), Positives = 69/131 (52%), Gaps = 4/131 (3%)
Frame = +2
Query: 459 DFSHLFVTSSFDWTVKLWTTKNNKPLYSFEDNADYVYDVMWSPTHPALFACVDGMGRLDL 518
D SH ++++S+D +K+W T + LY++ ++D V+DV PT PALF G++ L
Sbjct: 419 DXSH-YLSASYDHGIKVWNT-DLTSLYTYRAHSDIVWDVQCHPTEPALFLSCSQDGKIVL 592
Query: 519 WNLNND---TEVPTASISVEGNPALNRVRWTHSGREI-AVGDSEGQIVIYDVGEQIAVPR 574
W++ T +P S + P V+W + R + AVGD G + + D+ ++ V +
Sbjct: 593 WDVRESKPATCLPKCSSGFK--PTC--VQWQPNARNMYAVGDEGGHVSVQDL--RMVVEK 754
Query: 575 NDEWARFGRTL 585
N + R +
Sbjct: 755 NVSYQSHNRVV 787
>08355
Length = 498
Score = 46.6 bits (109), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 47/173 (27%), Positives = 71/173 (41%), Gaps = 16/173 (9%)
Frame = -1
Query: 320 YSGQIVLWDNRSNKRTPVQRTPLSAAAHTHPVYCVNVV--GTQNAHNLISISTDGKICSW 377
Y G + L++ PVQR HT PV+ V + N N SIS+DG+I W
Sbjct: 495 YDGSVALFNTIEKHNNPVQRCTADNGKHTDPVWQVRWQKDDSDNNMNFFSISSDGRIVHW 316
Query: 378 SL---DMLSHPQDSMELVHKQSKAVAVTSMSFPVGDVNN-----------FVVGSEEGSV 423
++ +M+ QD ++L A + V F+VG+EEG +
Sbjct: 315 TIVKNEMIY--QDIIQLTIPGPPAEGPDGIRMEVTGCGTAFDFHKHKDYLFLVGTEEGKM 142
Query: 424 YTACRHGSKAGISEMFEGHQGPITGIHCHAAVGAVDFSHLFVTSSFDWTVKLW 476
+ SKA S F G G + + +++ T S DW VK+W
Sbjct: 141 HVC----SKAYTSH-FIG-SGDAHNMAIYKVAWNRFHPNVYATCSADWNVKIW 1
>03387
Length = 1891
Score = 46.2 bits (108), Expect = 4e-05, Method: Compositional matrix adjust.
Identities = 61/265 (23%), Positives = 107/265 (40%), Gaps = 13/265 (4%)
Frame = +1
Query: 299 QSAVMSATFAKFHPNLVVGGTYSGQIVLWDNRSNKRTP---VQRTP-LSAAAHTHPVYCV 354
+ V A + +P ++ T S ++++D + P + P L H Y +
Sbjct: 202 EGEVNRARYMPQNPCIIATKTPSSDVLVFDYTKHPSKPDPSGECIPELRLKGHQKEGYGL 381
Query: 355 NVVGTQNAHNLISISTDGKICSWSLDMLSHPQDSMELVHKQSKAVAVTSMSFPVGDVNNF 414
+ N H L+S S D IC W ++ Q +V + TS+ V DV
Sbjct: 382 SWNPNLNGH-LLSASDDHTICLWDINST---QRESRVVDAHTIFTGHTSV---VEDVAWH 540
Query: 415 V--------VGSEEGSVYTACRHGSKAGISEMFEGHQGPITGIHCHAAVGAVDFSHLFVT 466
+ V ++ + R + + S + + H + C + +F + T
Sbjct: 541 LLHESLFGSVADDQKLMIWDTRSNTTSKPSHVVDAHTAEVN---CLSFNPYSEF--ILAT 705
Query: 467 SSFDWTVKLWTTKNNK-PLYSFEDNADYVYDVMWSPTHPALFACVDGMGRLDLWNLNNDT 525
S D TV LW +N K L+SFE + D ++ V WSP + + A RL +W+L+
Sbjct: 706 GSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLHVWDLSKIG 885
Query: 526 EVPTASISVEGNPALNRVRWTHSGR 550
E + +G P L + H+ +
Sbjct: 886 EEQLPEDAEDGPPELLFIHGGHTAK 960
>13278
Length = 870
Score = 43.1 bits (100), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 29/110 (26%), Positives = 51/110 (46%), Gaps = 4/110 (3%)
Frame = +1
Query: 461 SHLFVTSSFDWTVKLWTTKNNKPLYSFEDNADYVYDVMWSPTHPALFACVDGMGRLD--- 517
S + ++SFD TV+LW + L++ + + VY V +SP L + G D
Sbjct: 112 SLILASASFDSTVRLWEVERGLCLHTLTKHQEPVYSVAFSPDGKYLAS-----GSFDKCV 276
Query: 518 -LWNLNNDTEVPTASISVEGNPALNRVRWTHSGREIAVGDSEGQIVIYDV 566
+WN+ + V S +G + V W H G ++ S+G + + D+
Sbjct: 277 HIWNVQTGSLVH----SYKGTGGIFEVCWNHRGDKVGASASDGSVFVLDL 414
>02960
Length = 1577
Score = 41.2 bits (95), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 65/265 (24%), Positives = 100/265 (37%), Gaps = 30/265 (11%)
Frame = +2
Query: 277 DGVALVWNMKYKKTTPEYVFHCQSAVMSATFAKFHPN--LVVGGTYSGQIVLWDNRSN-- 332
D ALVW + + + C+ S P+ + G++ + LW N
Sbjct: 680 DQTALVWQWQRETNEVDCRLSCRGHAASVDCVAVSPDSQQMCTGSWDKMLKLWSTDCNVD 859
Query: 333 -----------------KRTPVQRTP-LSAAAHTHPVYCVNVVGTQNAHNLISISTDGKI 374
K T R P L+ + H V V + + H +++ S D +
Sbjct: 860 GDQSEDTERPSKKKKSAKSTTQTRVPVLTLSGHAEAVSAVRWL---DPHRVVTSSWDHSL 1030
Query: 375 CSWSLDMLSHPQDSMELVHKQSKAVAVTSMSFPVGDVNNFVVGSEEGSVYTA---CRHGS 431
W L H L+ + SKAV + S P+ + + GS + V C G
Sbjct: 1031RLWDL----HTAQQTSLI-QGSKAVLDVAYS-PLSHM--LITGSADRHVRLVDPRCSEGE 1186
Query: 432 KAGISEMFEGHQGPITGIHCHAAVGAVDFS----HLFVTSSFDWTVKLWTTKNNKP-LYS 486
+ F H G +TG VD+S HLF++ S+D +KLW T++ K LY
Sbjct: 1187TVKCA--FTSHTGWVTG---------VDWSPTREHLFLSGSYDNVLKLWDTRSPKATLYD 1333
Query: 487 FEDNADYVYDVMWSPTHPALFACVD 511
+ D + V WS L VD
Sbjct: 1334MNWHEDRILAVDWSIPELLLSGGVD 1408
>27475
Length = 369
Score = 34.3 bits (77), Expect = 0.14, Method: Compositional matrix adjust.
Identities = 27/78 (34%), Positives = 37/78 (47%), Gaps = 5/78 (6%)
Frame = +2
Query: 439 FEGHQGPITGIHCHAAVGAVDFS----HLFVTSSFDWTVKLWTTKNNKP-LYSFEDNADY 493
F H G +TG VD+S HLF++ S+D +KLW T++ K LY + D
Sbjct: 56 FTSHTGWVTG---------VDWSPTREHLFLSGSYDNVLKLWDTRSPKATLYDMNWHEDR 208
Query: 494 VYDVMWSPTHPALFACVD 511
+ V WS L VD
Sbjct: 209 ILAVDWSIPELLLSGGVD 262
>05393
Length = 904
Score = 34.3 bits (77), Expect = 0.15, Method: Compositional matrix adjust.
Identities = 24/93 (25%), Positives = 42/93 (45%), Gaps = 7/93 (7%)
Frame = +1
Query: 442 HQGPITGIHCHA-AVGAVDFSH----LFVTSSFDWTVKLWTTKNNKPLYSFEDNADY--V 494
H+ P+ + H+ V V S L +T+S D T+K+W +++KP + F N +
Sbjct: 187 HEKPVFSVGAHSSCVTGVCLSSQIPGLMITTSEDKTMKVWDIQDDKPTHVFSRNLKMKEL 366
Query: 495 YDVMWSPTHPALFACVDGMGRLDLWNLNNDTEV 527
+ P P +FA G +W++ V
Sbjct: 367 HCTGCCPEAPFVFAVGGGRREPKVWDIRESAAV 465
>01598
Length = 1545
Score = 33.9 bits (76), Expect = 0.22, Method: Compositional matrix adjust.
Identities = 29/109 (26%), Positives = 46/109 (42%), Gaps = 3/109 (2%)
Frame = +1
Query: 461 SHLFVTSSFDWTVKLWTTKNNKPLYSFEDNADYVYDVMWSPTHPALFACVDGMGRLDLWN 520
S T + D V LW + + + S +VY V SP P A G + WN
Sbjct: 415 SKTLCTFAQDRQVVLWDLETMEAVASMATLGGHVYCVRTSPIDPGRVAVGVGDSMIRTWN 594
Query: 521 LNNDTEVPTASISVEG-NPALNRVRWTHSGRE--IAVGDSEGQIVIYDV 566
++N T + +G + V W H +E + G +G+I ++DV
Sbjct: 595 MSNKTNPYDVTTLWQGIKSKVTAVAW-HPTKEGWLGFGTDDGRIGVFDV 738
Score = 29.6 bits (65), Expect = 4.0, Method: Compositional matrix adjust.
Identities = 70/291 (24%), Positives = 105/291 (36%), Gaps = 40/291 (13%)
Frame = +1
Query: 277 DGVALVWNMKYKKTTPEYVFHCQSAVMSATFAKFHP---NLVVGGTYSGQIVLWDNRSNK 333
D + WNM K + Q T +HP + GT G+I ++D S+K
Sbjct: 571 DSMIRTWNMSNKTNPYDVTTLWQGIKSKVTAVAWHPTKEGWLGFGTDDGRIGVFDVLSHK 750
Query: 334 RTPVQRTPLSAAAHTHPVYCVNVVGTQ----NAHNLISISTDGKICSWSLDMLSHPQ--- 386
+ T A+ V C + +L S+ D KI S +LS +
Sbjct: 751 MPTLSNTFHHRTAY---VVCWGPASLSPTDGKSFSLYSVG-DCKILEHSSAVLSRGEKKA 918
Query: 387 DSMELVHK-------QSKAVAVTSMSFPVGDVNNFVVGSEEGSVYT----------ACRH 429
+++++ K Q K + T +S+ D N VG++EGSVY A R
Sbjct: 919 NAIDITQKIGAVNSDQVKGLKATELSWSP-DQNAAAVGTDEGSVYVVTIQDLKIVAAIRT 1095
Query: 430 GSKAGISEMFEGH-----QGPITGIHCH--AAVG------AVDFSHLFVTSSFDWTVKLW 476
K + H Q P CH AA G VD + +F D L
Sbjct: 1096QQK--LINCVRWHPRLTDQSPAGSPCCHWLAAAGNDQVIHVVDLASVFAEREGDKETSLI 1269
Query: 477 TTKNNKPLYSFEDNADYVYDVMWSPTHPALFACVDGMGRLDLWNLNNDTEV 527
T L ++ V D+ WSP H A V +W++ T +
Sbjct: 1270LTS----LRELSGHSQRVTDMSWSPHHDARLVSVGYDAEAFVWDVQKGTAL 1410
>00432
Length = 1557
Score = 32.3 bits (72), Expect = 0.60, Method: Compositional matrix adjust.
Identities = 16/46 (34%), Positives = 23/46 (50%)
Frame = -1
Query: 205 PHELTEEEKQQILHSEEFLSFFDHSTRIVERALSEQINIFFDYSGR 250
PH LT + +Q H E+F + F TRI L + + FF + R
Sbjct: 300 PHALTNQFRQFRFHREKFFTQFIGRTRIFHAILRQFFHAFFGFPNR 163
>27465
Length = 658
Score = 31.6 bits (70), Expect = 0.90, Method: Compositional matrix adjust.
Identities = 25/97 (25%), Positives = 46/97 (47%), Gaps = 6/97 (6%)
Frame = -1
Query: 412 NNFVVGSEEGSVYTACRHGSKAGISEM--FEGHQGPITGIHCHAAVGAVDFSHLF----V 465
++F+ GS + + C+ A E+ EGH+ V A+ F++ F +
Sbjct: 322 SSFITGSYDRT----CKIWDTASAEELHTLEGHRN---------VVYAIAFNNPFGDKVI 182
Query: 466 TSSFDWTVKLWTTKNNKPLYSFEDNADYVYDVMWSPT 502
T SFD T KLW+T + K ++ + + V ++P+
Sbjct: 181 TGSFDKTCKLWSTADGKCYHTLRGHTAEIVCVSFNPS 71
>01768
Length = 1424
Score = 31.2 bits (69), Expect = 1.1, Method: Compositional matrix adjust.
Identities = 24/93 (25%), Positives = 42/93 (45%), Gaps = 2/93 (2%)
Frame = +3
Query: 476 WTTKNNKPLYSFEDNADYVYDVMWSPTHPALFACVDGMGRLDLWNLNND-TEVPTASISV 534
WTT+ + S+ + D V DV WSP +FA L +WN ++ ++
Sbjct: 804 WTTEKS----SYAAHTDSVEDVQWSPNEGNVFASCSVDRTLRIWNTQQKPSKANVLTVPE 971
Query: 535 EGNPALNRVRWTHSGRE-IAVGDSEGQIVIYDV 566
+ +N + W + +A G +G I I+D+
Sbjct: 972 AHSRDINVINWNPIEKHLLASGGDDGIIKIWDL 1070
>06996
Length = 1826
Score = 30.4 bits (67), Expect = 2.0, Method: Compositional matrix adjust.
Identities = 24/88 (27%), Positives = 40/88 (45%)
Frame = -3
Query: 375 CSWSLDMLSHPQDSMELVHKQSKAVAVTSMSFPVGDVNNFVVGSEEGSVYTACRHGSKAG 434
+WS++ S SME++H +V+++ S PV FVVG + YT +H +
Sbjct: 1818 LNWSIE-FSSDLHSMEIIHHFFSSVSISPFSVPV-----FVVG--QPIPYTDLKHKTNTY 1663
Query: 435 ISEMFEGHQGPITGIHCHAAVGAVDFSH 462
++F T H + + FSH
Sbjct: 1662 AKDLFRKEWDKQTDYKLH-EISPILFSH 1582
>26107
Length = 1338
Score = 30.4 bits (67), Expect = 2.2, Method: Compositional matrix adjust.
Identities = 16/68 (23%), Positives = 30/68 (44%)
Frame = -3
Query: 267 NNNEDAPHEPDGVALVWNMKYKKTTPEYVFHCQSAVMSATFAKFHPNLVVGGTYSGQIVL 326
N+++ D +W+++ ++ H + +V S P G G I+L
Sbjct: 1054 NDSQCLTASGDQTVALWDVETTTKVTTFIGH-KCSVRSVASCPSSPAQCASGARDGHIML 878
Query: 327 WDNRSNKR 334
WD+R NK+
Sbjct: 877 WDSRVNKK 854
>37180
Length = 681
Score = 30.4 bits (67), Expect = 2.3, Method: Compositional matrix adjust.
Identities = 28/112 (25%), Positives = 47/112 (41%), Gaps = 6/112 (5%)
Frame = +1
Query: 437 EMFEGHQGPITGIHCHAAVGAVDFSHLFVTSSFDWTVKLWTTKNNKPLYSFEDNADYVYD 496
+ GH ++ +H H L VTSS D T +LW +++ L + V+
Sbjct: 1 NVLNGHDQELSDVHAHPT------QRLVVTSSKDMTFRLWDFRDSALLVN-------VFQ 141
Query: 497 VMWSPTHPALFACVDGM------GRLDLWNLNNDTEVPTASISVEGNPALNR 542
P A+FA D + + +W++ N P A+I + A+NR
Sbjct: 142 GHTQPVTSAVFASGDKVVSGSDDRTVRVWDMRN-MRSPIATIRTDS--AVNR 288
>00561
Length = 1003
Score = 30.0 bits (66), Expect = 2.7, Method: Compositional matrix adjust.
Identities = 36/137 (26%), Positives = 58/137 (42%), Gaps = 4/137 (2%)
Frame = -3
Query: 436 SEMFEGHQGPITGIHCHAAVGAVDFSHLFVTSSFDWTVKLWTTKNNKPLYSFED-NADYV 494
+ FEGH + + A + V+ S D T+KLW T ED + D+V
Sbjct: 761 TRRFEGHTKDVLSVAFSAD------NRQIVSGSRDKTIKLWNTLAECKFTIQEDGHTDWV 600
Query: 495 YDVMWSPTH--PALFACVDGMGR-LDLWNLNNDTEVPTASISVEGNPALNRVRWTHSGRE 551
V +SP H P + +C G R + +WNL N + N LN V + G
Sbjct: 599 SCVRFSPNHSNPIIVSC--GWDRTVKVWNLAN---CKLKNNHHGHNGYLNTVTVSPDGSL 435
Query: 552 IAVGDSEGQIVIYDVGE 568
G + + +++D+ +
Sbjct: 434 CTSGGKDSKALLWDLND 384
>12140
Length = 727
Score = 29.3 bits (64), Expect = 4.3, Method: Compositional matrix adjust.
Identities = 23/107 (21%), Positives = 49/107 (45%), Gaps = 6/107 (5%)
Frame = +2
Query: 464 FVTSSFDWTVKLWTTKNNKPL--YSFEDNADYVYDVMWSPT----HPALFACVDGMGRLD 517
FV+ D VK+W + E ++D+V DV W+P+ + +C R+
Sbjct: 269 FVSGGCDNLVKIWREDETGWVEDQKLEGHSDWVRDVAWAPSIGLPRNVIASCSQDC-RVI 445
Query: 518 LWNLNNDTEVPTASISVEGNPALNRVRWTHSGREIAVGDSEGQIVIY 564
+W + + T+ I + + + V W+ +G +AV + ++ ++
Sbjct: 446 IWTNDGSSNQWTSRILNKFSDVVWHVSWSVTGNILAVSGGDNKVTLW 586
>01805
Length = 2124
Score = 28.9 bits (63), Expect = 5.6, Method: Compositional matrix adjust.
Identities = 35/145 (24%), Positives = 60/145 (41%), Gaps = 16/145 (11%)
Frame = -1
Query: 362 AHNLISISTDGKICSWSLDMLSHPQDSMELVHKQ---------SKAVAVTSMSFPV-GDV 411
A N S + + C+W HPQ+ L+ ++ S+ V G+V
Sbjct: 468 AMNFTQHSREVQCCNW------HPQEEQTLLTGSFDNTVKVVDCRSAETCHKSWTVEGEV 307
Query: 412 NNFVVGSEEGSVYTACRHGSKAGISEMFE-GHQGPITGIHCHAA-VGAVDFSH----LFV 465
V AC + G+ F+ H+ P+ + H++ V V S L +
Sbjct: 306 EKAVWNHHNPLQLLAC---TDKGMVYCFDIRHEKPVFSVGAHSSCVTGVCLSSQIPGLMI 136
Query: 466 TSSFDWTVKLWTTKNNKPLYSFEDN 490
T+S D T+K+W +++KP + F N
Sbjct: 135 TTSEDKTMKVWDIQDDKPTHVFSRN 61
>03395
Length = 2795
Score = 28.9 bits (63), Expect = 6.4, Method: Compositional matrix adjust.
Identities = 38/165 (23%), Positives = 60/165 (36%), Gaps = 3/165 (1%)
Frame = +2
Query: 315 VVGGTYSGQIVLWDNRSNKRTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNLISISTDGKI 374
+V G GQ+ +WD + T R L A H + N +S STDG
Sbjct: 41 LVSGGGEGQVRVWDIVKDMLTGKTRGDLVANMKEHKGKVTAIQIHTNDRCCVSASTDGST 220
Query: 375 CSWSLDMLSHPQDSMELVHKQSKAVAVTSMSFPVGDVNNFVVGSEEGSVYTACRHGSKAG 434
W D++++ + + L + K V F D++ G++ Y G G
Sbjct: 221 IIW--DLITNTRSQIVLANTLFKCVC-----FGGKDLHILTSGTDHKIGYWEVGDG---G 370
Query: 435 ISEMFEGHQGPITGIHCHAAVGAVDF---SHLFVTSSFDWTVKLW 476
+ EG Q A+ +D +T D +KLW
Sbjct: 371 LLRELEGSQ--------TGAINTIDIDRDGQTILTGGEDSLLKLW 481
>30429
Length = 674
Score = 28.5 bits (62), Expect = 7.4, Method: Compositional matrix adjust.
Identities = 15/49 (30%), Positives = 23/49 (46%), Gaps = 3/49 (6%)
Frame = -2
Query: 463 LFVTSSFDWTVKLWTTKNNKPLY---SFEDNADYVYDVMWSPTHPALFA 508
+ V FDW +K + N +PL+ SF D +V+ + P L A
Sbjct: 592 VLVKKCFDWKLKQFNNNNKRPLFHHNSFHDGNSHVWLCLCPSPLPNLIA 446
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000373224 | hsapiens_gene_ensembl | sarcolemma
associated protein [Source:RefSeq_peptide;Acc:NP_009090]
(506 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
14682 268 6e-80
14883 40 0.002
08467 29 5.2
09375 28 7.1
>14682
Length = 1076
Score = 268 bits (684), Expect(2) = 6e-80, Method: Compositional matrix adjust.
Identities = 138/236 (58%), Positives = 181/236 (76%), Gaps = 3/236 (1%)
Frame = -1
Query: 90 EESPPCEILSGDIIQFGVDVTENTR---KVTHGCIVSTIKLFLPDGMEARLRSDVIHAPL 146
EESP E+ SGD+IQFGV+V EN R K+THGCI++T+ L+ PDG EA+ P+
Sbjct: 1076 EESPMREVYSGDLIQFGVEVMENNRRGEKITHGCIIATLTLYHPDGREAK--------PV 921
Query: 147 PSPVDKVAANTPSMYSQELFQLSQYLQEALHREQMLEQKLATLQRLLAITQEASDTSWQA 206
P D T ++ SQ+L+QL+ +LQEALHRE+MLEQKL +LQ+L+ TQEA++ WQA
Sbjct: 920 PFLSDPNQPGT-TIQSQDLYQLAHFLQEALHREKMLEQKLGSLQQLVHXTQEAAEGGWQA 744
Query: 207 LIDEDRLLSRLEVMGNQLQACSKNQTEDSLRKELIALQEDKHNYETTAKESLRRVLQEKI 266
LIDED+LLSRLE++ NQL SKN +EDSLR+EL+ALQEDK NYETTAKESLRRVLQEK+
Sbjct: 743 LIDEDKLLSRLEMLENQLHIYSKNHSEDSLRQELVALQEDKINYETTAKESLRRVLQEKL 564
Query: 267 EVVRKLSEVERSLSNTEDECTHLKEMNERTQEELRELANKYNGAVNEIKDLSDKLK 322
+ V KLS++ERSL++ E EC HLKEM E +QEEL++LA +Y + E+ +L +KL+
Sbjct: 563 DAVTKLSDLERSLTSAEGECNHLKEMCESSQEELKQLATRYQDQLKEVMELQEKLQ 396
Score = 48.5 bits (114), Expect(2) = 6e-80, Method: Compositional matrix adjust.
Identities = 25/61 (40%), Positives = 41/61 (67%)
Frame = -3
Query: 342 LQHKIDEMEEKEQELQAKIEALQADNDFTNERLTALQVRLEHLQEKTLKECSSLGIQVDD 401
L K+++M ++E L AKIE+LQADNDF E+L A++ +LE +E +E +L + ++D
Sbjct: 339 LMEKLEDMIQQESSLSAKIESLQADNDFAREQLAAMKAKLESKKETNQEEDKALDLGLED 160
Query: 402 F 402
Sbjct: 159 I 157
>14883
Length = 954
Score = 40.0 bits (92), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 19/37 (51%), Positives = 28/37 (75%)
Frame = -3
Query: 342 LQHKIDEMEEKEQELQAKIEALQADNDFTNERLTALQ 378
L K+++M ++E L AKIE+LQADNDF E+L A++
Sbjct: 856 LMEKLEDMIQQESSLSAKIESLQADNDFAREQLAAMK 746
>08467
Length = 1621
Score = 28.9 bits (63), Expect = 5.2, Method: Compositional matrix adjust.
Identities = 13/48 (27%), Positives = 25/48 (52%)
Frame = -3
Query: 219 VMGNQLQACSKNQTEDSLRKELIALQEDKHNYETTAKESLRRVLQEKI 266
V+ N + + +T + + L + KH+YE TA + LR +Q ++
Sbjct: 902 VINNLQEGIKRMRTRTHVHTHITLLFKPKHSYEATANQPLRYFVQSRL 759
>09375
Length = 1361
Score = 28.5 bits (62), Expect = 7.1, Method: Compositional matrix adjust.
Identities = 25/91 (27%), Positives = 41/91 (45%)
Frame = -2
Query: 203 SWQALIDEDRLLSRLEVMGNQLQACSKNQTEDSLRKELIALQEDKHNYETTAKESLRRVL 262
SW+ D L+S ++ QLQ LRK++ + + N +T A LR +
Sbjct: 574 SWKTY--NDTLVSMIDSAQKQLQ---------DLRKKIQEINWQRKNEQTQAGTKLRELE 428
Query: 263 QEKIEVVRKLSEVERSLSNTEDECTHLKEMN 293
+ +V K E+ER+ E E ++E N
Sbjct: 427 TSWVGLVSKNYEIERACVELEKEVAEMEERN 335
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000339430 | hsapiens_gene_ensembl | Cytoplasmic
dynein 1 intermediate chain 2 (Dynein intermediate chain 2, cytosolic)
(DH IC-2) (Cytoplasmic dynein intermediate chain 2).
[Source:Uniprot/SWISSPROT;Acc:Q13409]
(612 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
20271 294 7e-80
14105 169 4e-42
12841 125 5e-29
07741 55 1e-07
20662 53 3e-07
08355 47 3e-05
03387 47 3e-05
13278 43 3e-04
02960 41 0.001
27475 34 0.13
05393 34 0.14
15972 34 0.16
01598 34 0.18
00432 32 0.60
27465 32 0.82
01768 31 1.3
26107 31 1.6
06996 31 1.8
37180 30 2.2
00561 30 3.3
12140 29 5.2
01805 29 5.2
03395 29 6.0
30429 28 7.3
>20271
Length = 567
Score = 294 bits (753), Expect = 7e-80, Method: Compositional matrix adjust.
Identities = 137/189 (72%), Positives = 157/189 (83%)
Frame = -1
Query: 356 HPVYCVNVVGTQNAHNLISISTDGKICSWSLDMLSHPQDSMELVHKQSKAVAVTSMSFPV 415
HPVYC+ VVGTQNAHNLIS+S DGK+CSWSLDMLS PQDSMEL HKQSK+VA T SF
Sbjct: 567 HPVYCITVVGTQNAHNLISVSNDGKLCSWSLDMLSQPQDSMELQHKQSKSVAATCFSFLS 388
Query: 416 GDVNNFVVGSEEGSVYTACRHGSKAGISEMFEGHQGPITGIHCHAAVGAVDFSHLFVTSS 475
GD NNF+VGSEE VY+A RHGSKAGI+E +EGHQGPIT I H A G +DFS F+T+S
Sbjct: 387 GDANNFIVGSEECLVYSASRHGSKAGINEAYEGHQGPITAIDTHHAAGQIDFSPFFLTAS 208
Query: 476 FDWTVKLWTTKNNKPLYSFEDNADYVYDVMWSPTHPALFACVDGMGRLDLWNLNNDTEVP 535
FDWTVKLW K K + SFEDN+DYV DV WSPT+PALF+CVD MGRLDLW+LN++TEVP
Sbjct: 207 FDWTVKLWNIKEQKYVCSFEDNSDYVSDVQWSPTNPALFSCVDIMGRLDLWHLNHETEVP 28
Query: 536 TASISVEGN 544
TAS+ V+GN
Sbjct: 27 TASVVVDGN 1
>14105
Length = 429
Score = 169 bits (427), Expect = 4e-42, Method: Compositional matrix adjust.
Identities = 75/111 (67%), Positives = 87/111 (78%)
Frame = +3
Query: 482 LWTTKNNKPLYSFEDNADYVYDVMWSPTHPALFACVDGMGRLDLWNLNNDTEVPTASISV 541
LW+ K+ KPLYSFEDN+DYV DV WSP HPALFA VDG GRLDLWNLN DTEVPTASI V
Sbjct: 3 LWSLKDTKPLYSFEDNSDYVMDVAWSPVHPALFAAVDGSGRLDLWNLNQDTEVPTASIVV 182
Query: 542 EGNPALNRVRWTHSGREIAVGDSEGQIVIYDVGEQIAVPRNDEWARFGRTL 592
+G PALNRV WT SG + +GD G++ +YDV E +A+P DEW+RF TL
Sbjct: 183 DGAPALNRVSWTPSGLHVTIGDESGKLYVYDVAEHLALPTRDEWSRFNATL 335
>12841
Length = 1364
Score = 125 bits (314), Expect = 5e-29, Method: Compositional matrix adjust.
Identities = 90/333 (27%), Positives = 144/333 (43%), Gaps = 28/333 (8%)
Frame = +1
Query: 246 FDERWS------KHRVVSCLDWSSQYPELLVASYNNNEDAPHEPDGVALVWNMKYKKTTP 299
D WS K R VSCL W+ P+L+ Y D ++ G+ W++K P
Sbjct: 361 LDRLWSYVCPLTKGRNVSCLAWNKSNPDLVAVGYGQF-DFTNQKSGLICCWSLK-NPEYP 534
Query: 300 EYVFHCQSAVMSATFAKFHPNLVVGGTYSGQIVLWDNRSNKRTPVQRTPLSAAAHTHPVY 359
E V+ V S F+ + N++ G Y G + +++ RS P+ + H PV+
Sbjct: 535 ERVYTSTHGVTSLDFSVANANILAAGYYDGGVAIYNVRSTSDEPILDNQETHGKHLGPVW 714
Query: 360 CVNVV------GTQNAHNLISISTDGKICSWSLDMLSHPQDSMELVH---------KQSK 404
+ + G + A LISISTDG++ WS+ + M L ++ K
Sbjct: 715 QIQWIEKERGSGEERAEVLISISTDGRVTQWSIRKGFESNNIMRLKKLPTRMAGKAREKK 894
Query: 405 AVAVTS-------MSFPVGDVNNFVVGSEEGSVYTACRHGSKAGISEMFEGHQGPITGIH 457
A S F D+N ++ G+EEG ++ C E + GH P+ I
Sbjct: 895 GEAFISRHAGGLCFDFHSRDLNVYLAGTEEGYIH-KCSCSYNEQYLETYSGHTAPVYHIR 1071
Query: 458 CHAAVGAVDFSHLFVTSSFDWTVKLWTTKNNKPLYSFEDNADYVYDVMWSPTHPALFACV 517
V S +F++ S DW+++LW P+ +F + V+DV WSP +FACV
Sbjct: 1072WSPFV-----SDIFLSCSADWSIRLWHQDRTTPILTFHSSTKTVHDVCWSPRSSTVFACV 1236
Query: 518 DGMGRLDLWNLNNDTEVPTASISVEGNPALNRV 550
G +++W+L T +I+ L V
Sbjct: 1237H-EGAVEVWDLAQSTLDAVITITPTSGAKLTSV 1332
>07741
Length = 2119
Score = 54.7 bits (130), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 43/165 (26%), Positives = 76/165 (46%), Gaps = 17/165 (10%)
Frame = +1
Query: 421 FVVGSEEGSVYTACRHGSKAGISEMFEGHQGPITGIHCHAAVGAVDFSH----LFVTSSF 476
F+VG+EEG V+ C + + + H + AV V ++H ++ T S
Sbjct: 157 FLVGTEEGKVH-VCSKAYTSHFIDTLDSH---------NMAVYKVAWNHYHPKIYATCSA 306
Query: 477 DWTVKLW-----------TTKNNKPLYSFEDNADYVYDVMWSPTHPALFACVDGMGRLDL 525
DW VK+W + + KPL+SF+ N + V DV W+P +FA V G++ +
Sbjct: 307 DWNVKIWENGGKPTDTGXDSLSRKPLFSFDLN-NSVGDVAWAPYSSTVFAAVTADGKVCV 483
Query: 526 WNLNNDTEVPTAS--ISVEGNPALNRVRWTHSGREIAVGDSEGQI 568
++L+ + P ++ + L + + S + VGD G +
Sbjct: 484 YDLSVNKYEPLCEQMVAQKKKTKLTHIEFNPSYPILIVGDDRGNV 618
Score = 29.6 bits (65), Expect = 3.6, Method: Compositional matrix adjust.
Identities = 20/81 (24%), Positives = 37/81 (45%), Gaps = 8/81 (9%)
Frame = +1
Query: 501 VYDVMWSPTHPALFACVDGMGRLDLW-NLNNDTEVPTASI------SVEGNPALNRVRWT 553
VY V W+ HP ++A + +W N T+ S+ S + N ++ V W
Sbjct: 250 VYKVAWNHYHPKIYATCSADWNVKIWENGGKPTDTGXDSLSRKPLFSFDLNNSVGDVAWA 429
Query: 554 -HSGREIAVGDSEGQIVIYDV 573
+S A ++G++ +YD+
Sbjct: 430 PYSSTVFAAVTADGKVCVYDL 492
>20662
Length = 1220
Score = 53.1 bits (126), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 39/131 (29%), Positives = 69/131 (52%), Gaps = 4/131 (3%)
Frame = +2
Query: 466 DFSHLFVTSSFDWTVKLWTTKNNKPLYSFEDNADYVYDVMWSPTHPALFACVDGMGRLDL 525
D SH ++++S+D +K+W T + LY++ ++D V+DV PT PALF G++ L
Sbjct: 419 DXSH-YLSASYDHGIKVWNT-DLTSLYTYRAHSDIVWDVQCHPTEPALFLSCSQDGKIVL 592
Query: 526 WNLNND---TEVPTASISVEGNPALNRVRWTHSGREI-AVGDSEGQIVIYDVGEQIAVPR 581
W++ T +P S + P V+W + R + AVGD G + + D+ ++ V +
Sbjct: 593 WDVRESKPATCLPKCSSGFK--PTC--VQWQPNARNMYAVGDEGGHVSVQDL--RMVVEK 754
Query: 582 NDEWARFGRTL 592
N + R +
Sbjct: 755 NVSYQSHNRVV 787
>08355
Length = 498
Score = 46.6 bits (109), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 47/173 (27%), Positives = 71/173 (41%), Gaps = 16/173 (9%)
Frame = -1
Query: 327 YSGQIVLWDNRSNKRTPVQRTPLSAAAHTHPVYCVNVV--GTQNAHNLISISTDGKICSW 384
Y G + L++ PVQR HT PV+ V + N N SIS+DG+I W
Sbjct: 495 YDGSVALFNTIEKHNNPVQRCTADNGKHTDPVWQVRWQKDDSDNNMNFFSISSDGRIVHW 316
Query: 385 SL---DMLSHPQDSMELVHKQSKAVAVTSMSFPVGDVNN-----------FVVGSEEGSV 430
++ +M+ QD ++L A + V F+VG+EEG +
Sbjct: 315 TIVKNEMIY--QDIIQLTIPGPPAEGPDGIRMEVTGCGTAFDFHKHKDYLFLVGTEEGKM 142
Query: 431 YTACRHGSKAGISEMFEGHQGPITGIHCHAAVGAVDFSHLFVTSSFDWTVKLW 483
+ SKA S F G G + + +++ T S DW VK+W
Sbjct: 141 HVC----SKAYTSH-FIG-SGDAHNMAIYKVAWNRFHPNVYATCSADWNVKIW 1
>03387
Length = 1891
Score = 46.6 bits (109), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 61/265 (23%), Positives = 107/265 (40%), Gaps = 13/265 (4%)
Frame = +1
Query: 306 QSAVMSATFAKFHPNLVVGGTYSGQIVLWDNRSNKRTP---VQRTP-LSAAAHTHPVYCV 361
+ V A + +P ++ T S ++++D + P + P L H Y +
Sbjct: 202 EGEVNRARYMPQNPCIIATKTPSSDVLVFDYTKHPSKPDPSGECIPELRLKGHQKEGYGL 381
Query: 362 NVVGTQNAHNLISISTDGKICSWSLDMLSHPQDSMELVHKQSKAVAVTSMSFPVGDVNNF 421
+ N H L+S S D IC W ++ Q +V + TS+ V DV
Sbjct: 382 SWNPNLNGH-LLSASDDHTICLWDINST---QRESRVVDAHTIFTGHTSV---VEDVAWH 540
Query: 422 V--------VGSEEGSVYTACRHGSKAGISEMFEGHQGPITGIHCHAAVGAVDFSHLFVT 473
+ V ++ + R + + S + + H + C + +F + T
Sbjct: 541 LLHESLFGSVADDQKLMIWDTRSNTTSKPSHVVDAHTAEVN---CLSFNPYSEF--ILAT 705
Query: 474 SSFDWTVKLWTTKNNK-PLYSFEDNADYVYDVMWSPTHPALFACVDGMGRLDLWNLNNDT 532
S D TV LW +N K L+SFE + D ++ V WSP + + A RL +W+L+
Sbjct: 706 GSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLHVWDLSKIG 885
Query: 533 EVPTASISVEGNPALNRVRWTHSGR 557
E + +G P L + H+ +
Sbjct: 886 EEQLPEDAEDGPPELLFIHGGHTAK 960
>13278
Length = 870
Score = 43.1 bits (100), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 29/110 (26%), Positives = 51/110 (46%), Gaps = 4/110 (3%)
Frame = +1
Query: 468 SHLFVTSSFDWTVKLWTTKNNKPLYSFEDNADYVYDVMWSPTHPALFACVDGMGRLD--- 524
S + ++SFD TV+LW + L++ + + VY V +SP L + G D
Sbjct: 112 SLILASASFDSTVRLWEVERGLCLHTLTKHQEPVYSVAFSPDGKYLAS-----GSFDKCV 276
Query: 525 -LWNLNNDTEVPTASISVEGNPALNRVRWTHSGREIAVGDSEGQIVIYDV 573
+WN+ + V S +G + V W H G ++ S+G + + D+
Sbjct: 277 HIWNVQTGSLVH----SYKGTGGIFEVCWNHRGDKVGASASDGSVFVLDL 414
>02960
Length = 1577
Score = 41.2 bits (95), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 65/265 (24%), Positives = 100/265 (37%), Gaps = 30/265 (11%)
Frame = +2
Query: 284 DGVALVWNMKYKKTTPEYVFHCQSAVMSATFAKFHPN--LVVGGTYSGQIVLWDNRSN-- 339
D ALVW + + + C+ S P+ + G++ + LW N
Sbjct: 680 DQTALVWQWQRETNEVDCRLSCRGHAASVDCVAVSPDSQQMCTGSWDKMLKLWSTDCNVD 859
Query: 340 -----------------KRTPVQRTP-LSAAAHTHPVYCVNVVGTQNAHNLISISTDGKI 381
K T R P L+ + H V V + + H +++ S D +
Sbjct: 860 GDQSEDTERPSKKKKSAKSTTQTRVPVLTLSGHAEAVSAVRWL---DPHRVVTSSWDHSL 1030
Query: 382 CSWSLDMLSHPQDSMELVHKQSKAVAVTSMSFPVGDVNNFVVGSEEGSVYTA---CRHGS 438
W L H L+ + SKAV + S P+ + + GS + V C G
Sbjct: 1031RLWDL----HTAQQTSLI-QGSKAVLDVAYS-PLS--HMLITGSADRHVRLVDPRCSEGE 1186
Query: 439 KAGISEMFEGHQGPITGIHCHAAVGAVDFS----HLFVTSSFDWTVKLWTTKNNKP-LYS 493
+ F H G +TG VD+S HLF++ S+D +KLW T++ K LY
Sbjct: 1187TVKCA--FTSHTGWVTG---------VDWSPTREHLFLSGSYDNVLKLWDTRSPKATLYD 1333
Query: 494 FEDNADYVYDVMWSPTHPALFACVD 518
+ D + V WS L VD
Sbjct: 1334MNWHEDRILAVDWSIPELLLSGGVD 1408
>27475
Length = 369
Score = 34.3 bits (77), Expect = 0.13, Method: Compositional matrix adjust.
Identities = 27/78 (34%), Positives = 37/78 (47%), Gaps = 5/78 (6%)
Frame = +2
Query: 446 FEGHQGPITGIHCHAAVGAVDFS----HLFVTSSFDWTVKLWTTKNNKP-LYSFEDNADY 500
F H G +TG VD+S HLF++ S+D +KLW T++ K LY + D
Sbjct: 56 FTSHTGWVTG---------VDWSPTREHLFLSGSYDNVLKLWDTRSPKATLYDMNWHEDR 208
Query: 501 VYDVMWSPTHPALFACVD 518
+ V WS L VD
Sbjct: 209 ILAVDWSIPELLLSGGVD 262
>05393
Length = 904
Score = 34.3 bits (77), Expect = 0.14, Method: Compositional matrix adjust.
Identities = 24/93 (25%), Positives = 43/93 (46%), Gaps = 7/93 (7%)
Frame = +1
Query: 449 HQGPITGIHCHAA-VGAVDFSH----LFVTSSFDWTVKLWTTKNNKPLYSFEDNADY--V 501
H+ P+ + H++ V V S L +T+S D T+K+W +++KP + F N +
Sbjct: 187 HEKPVFSVGAHSSCVTGVCLSSQIPGLMITTSEDKTMKVWDIQDDKPTHVFSRNLKMKEL 366
Query: 502 YDVMWSPTHPALFACVDGMGRLDLWNLNNDTEV 534
+ P P +FA G +W++ V
Sbjct: 367 HCTGCCPEAPFVFAVGGGRREPKVWDIRESAAV 465
>15972
Length = 1069
Score = 34.3 bits (77), Expect = 0.16, Method: Compositional matrix adjust.
Identities = 21/83 (25%), Positives = 38/83 (45%)
Frame = +3
Query: 446 FEGHQGPITGIHCHAAVGAVDFSHLFVTSSFDWTVKLWTTKNNKPLYSFEDNADYVYDVM 505
F GH+GP+ + H + L +T S D T++LW N + + + + V
Sbjct: 225 FSGHKGPVRHLAVHPS------GKLTLTVSQDRTLRLWNNMNGRIAF-ISNMKEAAESVR 383
Query: 506 WSPTHPALFACVDGMGRLDLWNL 528
W+P L+ V LD++++
Sbjct: 384 WAP--GGLYYVVAFRSHLDVYSV 446
>01598
Length = 1545
Score = 33.9 bits (76), Expect = 0.18, Method: Compositional matrix adjust.
Identities = 29/109 (26%), Positives = 46/109 (42%), Gaps = 3/109 (2%)
Frame = +1
Query: 468 SHLFVTSSFDWTVKLWTTKNNKPLYSFEDNADYVYDVMWSPTHPALFACVDGMGRLDLWN 527
S T + D V LW + + + S +VY V SP P A G + WN
Sbjct: 415 SKTLCTFAQDRQVVLWDLETMEAVASMATLGGHVYCVRTSPIDPGRVAVGVGDSMIRTWN 594
Query: 528 LNNDTEVPTASISVEG-NPALNRVRWTHSGRE--IAVGDSEGQIVIYDV 573
++N T + +G + V W H +E + G +G+I ++DV
Sbjct: 595 MSNKTNPYDVTTLWQGIKSKVTAVAW-HPTKEGWLGFGTDDGRIGVFDV 738
Score = 29.6 bits (65), Expect = 3.3, Method: Compositional matrix adjust.
Identities = 70/291 (24%), Positives = 105/291 (36%), Gaps = 40/291 (13%)
Frame = +1
Query: 284 DGVALVWNMKYKKTTPEYVFHCQSAVMSATFAKFHP---NLVVGGTYSGQIVLWDNRSNK 340
D + WNM K + Q T +HP + GT G+I ++D S+K
Sbjct: 571 DSMIRTWNMSNKTNPYDVTTLWQGIKSKVTAVAWHPTKEGWLGFGTDDGRIGVFDVLSHK 750
Query: 341 RTPVQRTPLSAAAHTHPVYCVNVVGTQ----NAHNLISISTDGKICSWSLDMLSHPQ--- 393
+ T A+ V C + +L S+ D KI S +LS +
Sbjct: 751 MPTLSNTFHHRTAY---VVCWGPASLSPTDGKSFSLYSVG-DCKILEHSSAVLSRGEKKA 918
Query: 394 DSMELVHK-------QSKAVAVTSMSFPVGDVNNFVVGSEEGSVYT----------ACRH 436
+++++ K Q K + T +S+ D N VG++EGSVY A R
Sbjct: 919 NAIDITQKIGAVNSDQVKGLKATELSWSP-DQNAAAVGTDEGSVYVVTIQDLKIVAAIRT 1095
Query: 437 GSKAGISEMFEGH-----QGPITGIHCH--AAVG------AVDFSHLFVTSSFDWTVKLW 483
K + H Q P CH AA G VD + +F D L
Sbjct: 1096QQK--LINCVRWHPRLTDQSPAGSPCCHWLAAAGNDQVIHVVDLASVFAEREGDKETSLI 1269
Query: 484 TTKNNKPLYSFEDNADYVYDVMWSPTHPALFACVDGMGRLDLWNLNNDTEV 534
T L ++ V D+ WSP H A V +W++ T +
Sbjct: 1270LTS----LRELSGHSQRVTDMSWSPHHDARLVSVGYDAEAFVWDVQKGTAL 1410
>00432
Length = 1557
Score = 32.3 bits (72), Expect = 0.60, Method: Compositional matrix adjust.
Identities = 16/46 (34%), Positives = 23/46 (50%)
Frame = -1
Query: 179 PHELTEEEKQQILHSEEFLSFFDHSTRIVERALSEQINIFFDYSGR 224
PH LT + +Q H E+F + F TRI L + + FF + R
Sbjct: 300 PHALTNQFRQFRFHREKFFTQFIGRTRIFHAILRQFFHAFFGFPNR 163
>27465
Length = 658
Score = 32.0 bits (71), Expect = 0.82, Method: Compositional matrix adjust.
Identities = 25/97 (25%), Positives = 46/97 (47%), Gaps = 6/97 (6%)
Frame = -1
Query: 419 NNFVVGSEEGSVYTACRHGSKAGISEM--FEGHQGPITGIHCHAAVGAVDFSHLF----V 472
++F+ GS + + C+ A E+ EGH+ V A+ F++ F +
Sbjct: 322 SSFITGSYDRT----CKIWDTASAEELHTLEGHRN---------VVYAIAFNNPFGDKVI 182
Query: 473 TSSFDWTVKLWTTKNNKPLYSFEDNADYVYDVMWSPT 509
T SFD T KLW+T + K ++ + + V ++P+
Sbjct: 181 TGSFDKTCKLWSTADGKCYHTLRGHTAEIVCVSFNPS 71
>01768
Length = 1424
Score = 31.2 bits (69), Expect = 1.3, Method: Compositional matrix adjust.
Identities = 24/93 (25%), Positives = 42/93 (45%), Gaps = 2/93 (2%)
Frame = +3
Query: 483 WTTKNNKPLYSFEDNADYVYDVMWSPTHPALFACVDGMGRLDLWNLNND-TEVPTASISV 541
WTT+ + S+ + D V DV WSP +FA L +WN ++ ++
Sbjct: 804 WTTEKS----SYAAHTDSVEDVQWSPNEGNVFASCSVDRTLRIWNTQQKPSKANVLTVPE 971
Query: 542 EGNPALNRVRWTHSGRE-IAVGDSEGQIVIYDV 573
+ +N + W + +A G +G I I+D+
Sbjct: 972 AHSRDINVINWNPIEKHLLASGGDDGIIKIWDL 1070
>26107
Length = 1338
Score = 30.8 bits (68), Expect = 1.6, Method: Compositional matrix adjust.
Identities = 24/95 (25%), Positives = 36/95 (37%), Gaps = 1/95 (1%)
Frame = -3
Query: 248 ERWSKHR-VVSCLDWSSQYPELLVASYNNNEDAPHEPDGVALVWNMKYKKTTPEYVFHCQ 306
RW H V W S + L AS D +W+++ ++ H +
Sbjct: 1105 HRWXAHNNAVFDYSWISNDSQCLTAS----------GDQTVALWDVETTTKVTTFIGH-K 959
Query: 307 SAVMSATFAKFHPNLVVGGTYSGQIVLWDNRSNKR 341
+V S P G G I+LWD+R NK+
Sbjct: 958 CSVRSVASCPSSPAQCASGARDGHIMLWDSRVNKK 854
>06996
Length = 1826
Score = 30.8 bits (68), Expect = 1.8, Method: Compositional matrix adjust.
Identities = 24/88 (27%), Positives = 40/88 (45%)
Frame = -3
Query: 382 CSWSLDMLSHPQDSMELVHKQSKAVAVTSMSFPVGDVNNFVVGSEEGSVYTACRHGSKAG 441
+WS++ S SME++H +V+++ S PV FVVG + YT +H +
Sbjct: 1818 LNWSIE-FSSDLHSMEIIHHFFSSVSISPFSVPV-----FVVG--QPIPYTDLKHKTNTY 1663
Query: 442 ISEMFEGHQGPITGIHCHAAVGAVDFSH 469
++F T H + + FSH
Sbjct: 1662 AKDLFRKEWDKQTDYKLH-EISPILFSH 1582
>37180
Length = 681
Score = 30.4 bits (67), Expect = 2.2, Method: Compositional matrix adjust.
Identities = 30/112 (26%), Positives = 48/112 (42%), Gaps = 6/112 (5%)
Frame = +1
Query: 444 EMFEGHQGPITGIHCHAAVGAVDFSHLFVTSSFDWTVKLWTTKNNKPLYSFEDNADYVYD 503
+ GH ++ +H H L VTSS D T +LW +++ L + V+
Sbjct: 1 NVLNGHDQELSDVHAHPT------QRLVVTSSKDMTFRLWDFRDSALLVN-------VFQ 141
Query: 504 VMWSPTHPALFACVDGM--GRLD----LWNLNNDTEVPTASISVEGNPALNR 549
P A+FA D + G D +W++ N P A+I + A+NR
Sbjct: 142 GHTQPVTSAVFASGDKVVSGSDDRTVRVWDMRN-MRSPIATIRTDS--AVNR 288
>00561
Length = 1003
Score = 29.6 bits (65), Expect = 3.3, Method: Compositional matrix adjust.
Identities = 36/137 (26%), Positives = 58/137 (42%), Gaps = 4/137 (2%)
Frame = -3
Query: 443 SEMFEGHQGPITGIHCHAAVGAVDFSHLFVTSSFDWTVKLWTTKNNKPLYSFED-NADYV 501
+ FEGH + + A + V+ S D T+KLW T ED + D+V
Sbjct: 761 TRRFEGHTKDVLSVAFSAD------NRQIVSGSRDKTIKLWNTLAECKFTIQEDGHTDWV 600
Query: 502 YDVMWSPTH--PALFACVDGMGR-LDLWNLNNDTEVPTASISVEGNPALNRVRWTHSGRE 558
V +SP H P + +C G R + +WNL N + N LN V + G
Sbjct: 599 SCVRFSPNHSNPIIVSC--GWDRTVKVWNLAN---CKLKNNHHGHNGYLNTVTVSPDGSL 435
Query: 559 IAVGDSEGQIVIYDVGE 575
G + + +++D+ +
Sbjct: 434 CTSGGKDSKALLWDLND 384
>12140
Length = 727
Score = 29.3 bits (64), Expect = 5.2, Method: Compositional matrix adjust.
Identities = 23/107 (21%), Positives = 49/107 (45%), Gaps = 6/107 (5%)
Frame = +2
Query: 471 FVTSSFDWTVKLWTTKNNKPL--YSFEDNADYVYDVMWSPT----HPALFACVDGMGRLD 524
FV+ D VK+W + E ++D+V DV W+P+ + +C R+
Sbjct: 269 FVSGGCDNLVKIWREDETGWVEDQKLEGHSDWVRDVAWAPSIGLPRNVIASCSQDC-RVI 445
Query: 525 LWNLNNDTEVPTASISVEGNPALNRVRWTHSGREIAVGDSEGQIVIY 571
+W + + T+ I + + + V W+ +G +AV + ++ ++
Sbjct: 446 IWTNDGSSNQWTSRILNKFSDVVWHVSWSVTGNILAVSGGDNKVTLW 586
>01805
Length = 2124
Score = 29.3 bits (64), Expect = 5.2, Method: Compositional matrix adjust.
Identities = 17/54 (31%), Positives = 30/54 (55%), Gaps = 5/54 (9%)
Frame = -1
Query: 449 HQGPITGIHCHAA-VGAVDFSH----LFVTSSFDWTVKLWTTKNNKPLYSFEDN 497
H+ P+ + H++ V V S L +T+S D T+K+W +++KP + F N
Sbjct: 222 HEKPVFSVGAHSSCVTGVCLSSQIPGLMITTSEDKTMKVWDIQDDKPTHVFSRN 61
>03395
Length = 2795
Score = 28.9 bits (63), Expect = 6.0, Method: Compositional matrix adjust.
Identities = 38/165 (23%), Positives = 60/165 (36%), Gaps = 3/165 (1%)
Frame = +2
Query: 322 VVGGTYSGQIVLWDNRSNKRTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNLISISTDGKI 381
+V G GQ+ +WD + T R L A H + N +S STDG
Sbjct: 41 LVSGGGEGQVRVWDIVKDMLTGKTRGDLVANMKEHKGKVTAIQIHTNDRCCVSASTDGST 220
Query: 382 CSWSLDMLSHPQDSMELVHKQSKAVAVTSMSFPVGDVNNFVVGSEEGSVYTACRHGSKAG 441
W D++++ + + L + K V F D++ G++ Y G G
Sbjct: 221 IIW--DLITNTRSQIVLANTLFKCVC-----FGGKDLHILTSGTDHKIGYWEVGDG---G 370
Query: 442 ISEMFEGHQGPITGIHCHAAVGAVDF---SHLFVTSSFDWTVKLW 483
+ EG Q A+ +D +T D +KLW
Sbjct: 371 LLRELEGSQ--------TGAINTIDIDRDGQTILTGGEDSLLKLW 481
>30429
Length = 674
Score = 28.5 bits (62), Expect = 7.3, Method: Compositional matrix adjust.
Identities = 15/49 (30%), Positives = 23/49 (46%), Gaps = 3/49 (6%)
Frame = -2
Query: 470 LFVTSSFDWTVKLWTTKNNKPLY---SFEDNADYVYDVMWSPTHPALFA 515
+ V FDW +K + N +PL+ SF D +V+ + P L A
Sbjct: 592 VLVKKCFDWKLKQFNNNNKRPLFHHNSFHDGNSHVWLCLCPSPLPNLIA 446
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000380308 | hsapiens_gene_ensembl | Cytoplasmic
dynein 1 intermediate chain 2 (Dynein intermediate chain 2, cytosolic)
(DH IC-2) (Cytoplasmic dynein intermediate chain 2).
[Source:Uniprot/SWISSPROT;Acc:Q13409]
(638 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
20271 294 7e-80
14105 168 5e-42
12841 125 6e-29
07741 55 1e-07
20662 53 3e-07
08355 47 3e-05
03387 47 3e-05
13278 43 3e-04
02960 41 0.001
05393 35 0.13
27475 34 0.15
15972 34 0.16
01598 34 0.18
00432 32 0.61
27465 32 0.89
01768 31 1.3
26107 31 1.7
06996 30 2.1
37180 30 2.4
00561 30 2.9
12140 29 4.8
01805 29 5.5
03395 29 6.7
30429 29 7.3
>20271
Length = 567
Score = 294 bits (752), Expect = 7e-80, Method: Compositional matrix adjust.
Identities = 137/189 (72%), Positives = 157/189 (83%)
Frame = -1
Query: 382 HPVYCVNVVGTQNAHNLISISTDGKICSWSLDMLSHPQDSMELVHKQSKAVAVTSMSFPV 441
HPVYC+ VVGTQNAHNLIS+S DGK+CSWSLDMLS PQDSMEL HKQSK+VA T SF
Sbjct: 567 HPVYCITVVGTQNAHNLISVSNDGKLCSWSLDMLSQPQDSMELQHKQSKSVAATCFSFLS 388
Query: 442 GDVNNFVVGSEEGSVYTACRHGSKAGISEMFEGHQGPITGIHCHAAVGAVDFSHLFVTSS 501
GD NNF+VGSEE VY+A RHGSKAGI+E +EGHQGPIT I H A G +DFS F+T+S
Sbjct: 387 GDANNFIVGSEECLVYSASRHGSKAGINEAYEGHQGPITAIDTHHAAGQIDFSPFFLTAS 208
Query: 502 FDWTVKLWTTKNNKPLYSFEDNADYVYDVMWSPTHPALFACVDGMGRLDLWNLNNDTEVP 561
FDWTVKLW K K + SFEDN+DYV DV WSPT+PALF+CVD MGRLDLW+LN++TEVP
Sbjct: 207 FDWTVKLWNIKEQKYVCSFEDNSDYVSDVQWSPTNPALFSCVDIMGRLDLWHLNHETEVP 28
Query: 562 TASISVEGN 570
TAS+ V+GN
Sbjct: 27 TASVVVDGN 1
>14105
Length = 429
Score = 168 bits (426), Expect = 5e-42, Method: Compositional matrix adjust.
Identities = 75/111 (67%), Positives = 87/111 (78%)
Frame = +3
Query: 508 LWTTKNNKPLYSFEDNADYVYDVMWSPTHPALFACVDGMGRLDLWNLNNDTEVPTASISV 567
LW+ K+ KPLYSFEDN+DYV DV WSP HPALFA VDG GRLDLWNLN DTEVPTASI V
Sbjct: 3 LWSLKDTKPLYSFEDNSDYVMDVAWSPVHPALFAAVDGSGRLDLWNLNQDTEVPTASIVV 182
Query: 568 EGNPALNRVRWTHSGREIAVGDSEGQIVIYDVGEQIAVPRNDEWARFGRTL 618
+G PALNRV WT SG + +GD G++ +YDV E +A+P DEW+RF TL
Sbjct: 183 DGAPALNRVSWTPSGLHVTIGDESGKLYVYDVAEHLALPTRDEWSRFNATL 335
>12841
Length = 1364
Score = 125 bits (314), Expect = 6e-29, Method: Compositional matrix adjust.
Identities = 90/333 (27%), Positives = 144/333 (43%), Gaps = 28/333 (8%)
Frame = +1
Query: 272 FDERWS------KHRVVSCLDWSSQYPELLVASYNNNEDAPHEPDGVALVWNMKYKKTTP 325
D WS K R VSCL W+ P+L+ Y D ++ G+ W++K P
Sbjct: 361 LDRLWSYVCPLTKGRNVSCLAWNKSNPDLVAVGYGQF-DFTNQKSGLICCWSLK-NPEYP 534
Query: 326 EYVFHCQSAVMSATFAKFHPNLVVGGTYSGQIVLWDNRSNKRTPVQRTPLSAAAHTHPVY 385
E V+ V S F+ + N++ G Y G + +++ RS P+ + H PV+
Sbjct: 535 ERVYTSTHGVTSLDFSVANANILAAGYYDGGVAIYNVRSTSDEPILDNQETHGKHLGPVW 714
Query: 386 CVNVV------GTQNAHNLISISTDGKICSWSLDMLSHPQDSMELVH---------KQSK 430
+ + G + A LISISTDG++ WS+ + M L ++ K
Sbjct: 715 QIQWIEKERGSGEERAEVLISISTDGRVTQWSIRKGFESNNIMRLKKLPTRMAGKAREKK 894
Query: 431 AVAVTS-------MSFPVGDVNNFVVGSEEGSVYTACRHGSKAGISEMFEGHQGPITGIH 483
A S F D+N ++ G+EEG ++ C E + GH P+ I
Sbjct: 895 GEAFISRHAGGLCFDFHSRDLNVYLAGTEEGYIH-KCSCSYNEQYLETYSGHTAPVYHIR 1071
Query: 484 CHAAVGAVDFSHLFVTSSFDWTVKLWTTKNNKPLYSFEDNADYVYDVMWSPTHPALFACV 543
V S +F++ S DW+++LW P+ +F + V+DV WSP +FACV
Sbjct: 1072WSPFV-----SDIFLSCSADWSIRLWHQDRTTPILTFHSSTKTVHDVCWSPRSSTVFACV 1236
Query: 544 DGMGRLDLWNLNNDTEVPTASISVEGNPALNRV 576
G +++W+L T +I+ L V
Sbjct: 1237H-EGAVEVWDLAQSTLDAVITITPTSGAKLTSV 1332
>07741
Length = 2119
Score = 54.7 bits (130), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 43/165 (26%), Positives = 76/165 (46%), Gaps = 17/165 (10%)
Frame = +1
Query: 447 FVVGSEEGSVYTACRHGSKAGISEMFEGHQGPITGIHCHAAVGAVDFSH----LFVTSSF 502
F+VG+EEG V+ C + + + H + AV V ++H ++ T S
Sbjct: 157 FLVGTEEGKVH-VCSKAYTSHFIDTLDSH---------NMAVYKVAWNHYHPKIYATCSA 306
Query: 503 DWTVKLWT-----------TKNNKPLYSFEDNADYVYDVMWSPTHPALFACVDGMGRLDL 551
DW VK+W + + KPL+SF+ N + V DV W+P +FA V G++ +
Sbjct: 307 DWNVKIWENGGKPTDTGXDSLSRKPLFSFDLN-NSVGDVAWAPYSSTVFAAVTADGKVCV 483
Query: 552 WNLNNDTEVPTAS--ISVEGNPALNRVRWTHSGREIAVGDSEGQI 594
++L+ + P ++ + L + + S + VGD G +
Sbjct: 484 YDLSVNKYEPLCEQMVAQKKKTKLTHIEFNPSYPILIVGDDRGNV 618
Score = 29.6 bits (65), Expect = 3.7, Method: Compositional matrix adjust.
Identities = 20/81 (24%), Positives = 37/81 (45%), Gaps = 8/81 (9%)
Frame = +1
Query: 527 VYDVMWSPTHPALFACVDGMGRLDLW-NLNNDTEVPTASI------SVEGNPALNRVRWT 579
VY V W+ HP ++A + +W N T+ S+ S + N ++ V W
Sbjct: 250 VYKVAWNHYHPKIYATCSADWNVKIWENGGKPTDTGXDSLSRKPLFSFDLNNSVGDVAWA 429
Query: 580 -HSGREIAVGDSEGQIVIYDV 599
+S A ++G++ +YD+
Sbjct: 430 PYSSTVFAAVTADGKVCVYDL 492
>20662
Length = 1220
Score = 53.1 bits (126), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 39/131 (29%), Positives = 69/131 (52%), Gaps = 4/131 (3%)
Frame = +2
Query: 492 DFSHLFVTSSFDWTVKLWTTKNNKPLYSFEDNADYVYDVMWSPTHPALFACVDGMGRLDL 551
D SH ++++S+D +K+W T + LY++ ++D V+DV PT PALF G++ L
Sbjct: 419 DXSH-YLSASYDHGIKVWNT-DLTSLYTYRAHSDIVWDVQCHPTEPALFLSCSQDGKIVL 592
Query: 552 WNLNND---TEVPTASISVEGNPALNRVRWTHSGREI-AVGDSEGQIVIYDVGEQIAVPR 607
W++ T +P S + P V+W + R + AVGD G + + D+ ++ V +
Sbjct: 593 WDVRESKPATCLPKCSSGFK--PTC--VQWQPNARNMYAVGDEGGHVSVQDL--RMVVEK 754
Query: 608 NDEWARFGRTL 618
N + R +
Sbjct: 755 NVSYQSHNRVV 787
>08355
Length = 498
Score = 46.6 bits (109), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 47/173 (27%), Positives = 71/173 (41%), Gaps = 16/173 (9%)
Frame = -1
Query: 353 YSGQIVLWDNRSNKRTPVQRTPLSAAAHTHPVYCVNVV--GTQNAHNLISISTDGKICSW 410
Y G + L++ PVQR HT PV+ V + N N SIS+DG+I W
Sbjct: 495 YDGSVALFNTIEKHNNPVQRCTADNGKHTDPVWQVRWQKDDSDNNMNFFSISSDGRIVHW 316
Query: 411 SL---DMLSHPQDSMELVHKQSKAVAVTSMSFPVGDVNN-----------FVVGSEEGSV 456
++ +M+ QD ++L A + V F+VG+EEG +
Sbjct: 315 TIVKNEMIY--QDIIQLTIPGPPAEGPDGIRMEVTGCGTAFDFHKHKDYLFLVGTEEGKM 142
Query: 457 YTACRHGSKAGISEMFEGHQGPITGIHCHAAVGAVDFSHLFVTSSFDWTVKLW 509
+ SKA S F G G + + +++ T S DW VK+W
Sbjct: 141 HVC----SKAYTSH-FIG-SGDAHNMAIYKVAWNRFHPNVYATCSADWNVKIW 1
>03387
Length = 1891
Score = 46.6 bits (109), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 61/265 (23%), Positives = 107/265 (40%), Gaps = 13/265 (4%)
Frame = +1
Query: 332 QSAVMSATFAKFHPNLVVGGTYSGQIVLWDNRSNKRTP---VQRTP-LSAAAHTHPVYCV 387
+ V A + +P ++ T S ++++D + P + P L H Y +
Sbjct: 202 EGEVNRARYMPQNPCIIATKTPSSDVLVFDYTKHPSKPDPSGECIPELRLKGHQKEGYGL 381
Query: 388 NVVGTQNAHNLISISTDGKICSWSLDMLSHPQDSMELVHKQSKAVAVTSMSFPVGDVNNF 447
+ N H L+S S D IC W ++ Q +V + TS+ V DV
Sbjct: 382 SWNPNLNGH-LLSASDDHTICLWDINST---QRESRVVDAHTIFTGHTSV---VEDVAWH 540
Query: 448 V--------VGSEEGSVYTACRHGSKAGISEMFEGHQGPITGIHCHAAVGAVDFSHLFVT 499
+ V ++ + R + + S + + H + C + +F + T
Sbjct: 541 LLHESLFGSVADDQKLMIWDTRSNTTSKPSHVVDAHTAEVN---CLSFNPYSEF--ILAT 705
Query: 500 SSFDWTVKLWTTKNNK-PLYSFEDNADYVYDVMWSPTHPALFACVDGMGRLDLWNLNNDT 558
S D TV LW +N K L+SFE + D ++ V WSP + + A RL +W+L+
Sbjct: 706 GSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLHVWDLSKIG 885
Query: 559 EVPTASISVEGNPALNRVRWTHSGR 583
E + +G P L + H+ +
Sbjct: 886 EEQLPEDAEDGPPELLFIHGGHTAK 960
>13278
Length = 870
Score = 43.1 bits (100), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 29/110 (26%), Positives = 51/110 (46%), Gaps = 4/110 (3%)
Frame = +1
Query: 494 SHLFVTSSFDWTVKLWTTKNNKPLYSFEDNADYVYDVMWSPTHPALFACVDGMGRLD--- 550
S + ++SFD TV+LW + L++ + + VY V +SP L + G D
Sbjct: 112 SLILASASFDSTVRLWEVERGLCLHTLTKHQEPVYSVAFSPDGKYLAS-----GSFDKCV 276
Query: 551 -LWNLNNDTEVPTASISVEGNPALNRVRWTHSGREIAVGDSEGQIVIYDV 599
+WN+ + V S +G + V W H G ++ S+G + + D+
Sbjct: 277 HIWNVQTGSLVH----SYKGTGGIFEVCWNHRGDKVGASASDGSVFVLDL 414
>02960
Length = 1577
Score = 41.2 bits (95), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 65/265 (24%), Positives = 100/265 (37%), Gaps = 30/265 (11%)
Frame = +2
Query: 310 DGVALVWNMKYKKTTPEYVFHCQSAVMSATFAKFHPN--LVVGGTYSGQIVLWDNRSN-- 365
D ALVW + + + C+ S P+ + G++ + LW N
Sbjct: 680 DQTALVWQWQRETNEVDCRLSCRGHAASVDCVAVSPDSQQMCTGSWDKMLKLWSTDCNVD 859
Query: 366 -----------------KRTPVQRTP-LSAAAHTHPVYCVNVVGTQNAHNLISISTDGKI 407
K T R P L+ + H V V + + H +++ S D +
Sbjct: 860 GDQSEDTERPSKKKKSAKSTTQTRVPVLTLSGHAEAVSAVRWL---DPHRVVTSSWDHSL 1030
Query: 408 CSWSLDMLSHPQDSMELVHKQSKAVAVTSMSFPVGDVNNFVVGSEEGSVYTA---CRHGS 464
W L H L+ + SKAV + S P+ + + GS + V C G
Sbjct: 1031RLWDL----HTAQQTSLI-QGSKAVLDVAYS-PLSHM--LITGSADRHVRLVDPRCSEGE 1186
Query: 465 KAGISEMFEGHQGPITGIHCHAAVGAVDFS----HLFVTSSFDWTVKLWTTKNNKP-LYS 519
+ F H G +TG VD+S HLF++ S+D +KLW T++ K LY
Sbjct: 1187TVKCA--FTSHTGWVTG---------VDWSPTREHLFLSGSYDNVLKLWDTRSPKATLYD 1333
Query: 520 FEDNADYVYDVMWSPTHPALFACVD 544
+ D + V WS L VD
Sbjct: 1334MNWHEDRILAVDWSIPELLLSGGVD 1408
>05393
Length = 904
Score = 34.7 bits (78), Expect = 0.13, Method: Compositional matrix adjust.
Identities = 24/93 (25%), Positives = 42/93 (45%), Gaps = 7/93 (7%)
Frame = +1
Query: 475 HQGPITGIHCHA-AVGAVDFSH----LFVTSSFDWTVKLWTTKNNKPLYSFEDNADY--V 527
H+ P+ + H+ V V S L +T+S D T+K+W +++KP + F N +
Sbjct: 187 HEKPVFSVGAHSSCVTGVCLSSQIPGLMITTSEDKTMKVWDIQDDKPTHVFSRNLKMKEL 366
Query: 528 YDVMWSPTHPALFACVDGMGRLDLWNLNNDTEV 560
+ P P +FA G +W++ V
Sbjct: 367 HCTGCCPEAPFVFAVGGGRREPKVWDIRESAAV 465
>27475
Length = 369
Score = 34.3 bits (77), Expect = 0.15, Method: Compositional matrix adjust.
Identities = 27/78 (34%), Positives = 37/78 (47%), Gaps = 5/78 (6%)
Frame = +2
Query: 472 FEGHQGPITGIHCHAAVGAVDFS----HLFVTSSFDWTVKLWTTKNNKP-LYSFEDNADY 526
F H G +TG VD+S HLF++ S+D +KLW T++ K LY + D
Sbjct: 56 FTSHTGWVTG---------VDWSPTREHLFLSGSYDNVLKLWDTRSPKATLYDMNWHEDR 208
Query: 527 VYDVMWSPTHPALFACVD 544
+ V WS L VD
Sbjct: 209 ILAVDWSIPELLLSGGVD 262
>15972
Length = 1069
Score = 34.3 bits (77), Expect = 0.16, Method: Compositional matrix adjust.
Identities = 21/83 (25%), Positives = 38/83 (45%)
Frame = +3
Query: 472 FEGHQGPITGIHCHAAVGAVDFSHLFVTSSFDWTVKLWTTKNNKPLYSFEDNADYVYDVM 531
F GH+GP+ + H + L +T S D T++LW N + + + + V
Sbjct: 225 FSGHKGPVRHLAVHPS------GKLTLTVSQDRTLRLWNNMNGRIAF-ISNMKEAAESVR 383
Query: 532 WSPTHPALFACVDGMGRLDLWNL 554
W+P L+ V LD++++
Sbjct: 384 WAP--GGLYYVVAFRSHLDVYSV 446
>01598
Length = 1545
Score = 34.3 bits (77), Expect = 0.18, Method: Compositional matrix adjust.
Identities = 29/109 (26%), Positives = 46/109 (42%), Gaps = 3/109 (2%)
Frame = +1
Query: 494 SHLFVTSSFDWTVKLWTTKNNKPLYSFEDNADYVYDVMWSPTHPALFACVDGMGRLDLWN 553
S T + D V LW + + + S +VY V SP P A G + WN
Sbjct: 415 SKTLCTFAQDRQVVLWDLETMEAVASMATLGGHVYCVRTSPIDPGRVAVGVGDSMIRTWN 594
Query: 554 LNNDTEVPTASISVEG-NPALNRVRWTHSGRE--IAVGDSEGQIVIYDV 599
++N T + +G + V W H +E + G +G+I ++DV
Sbjct: 595 MSNKTNPYDVTTLWQGIKSKVTAVAW-HPTKEGWLGFGTDDGRIGVFDV 738
Score = 29.6 bits (65), Expect = 3.6, Method: Compositional matrix adjust.
Identities = 70/291 (24%), Positives = 105/291 (36%), Gaps = 40/291 (13%)
Frame = +1
Query: 310 DGVALVWNMKYKKTTPEYVFHCQSAVMSATFAKFHP---NLVVGGTYSGQIVLWDNRSNK 366
D + WNM K + Q T +HP + GT G+I ++D S+K
Sbjct: 571 DSMIRTWNMSNKTNPYDVTTLWQGIKSKVTAVAWHPTKEGWLGFGTDDGRIGVFDVLSHK 750
Query: 367 RTPVQRTPLSAAAHTHPVYCVNVVGTQ----NAHNLISISTDGKICSWSLDMLSHPQ--- 419
+ T A+ V C + +L S+ D KI S +LS +
Sbjct: 751 MPTLSNTFHHRTAY---VVCWGPASLSPTDGKSFSLYSVG-DCKILEHSSAVLSRGEKKA 918
Query: 420 DSMELVHK-------QSKAVAVTSMSFPVGDVNNFVVGSEEGSVYT----------ACRH 462
+++++ K Q K + T +S+ D N VG++EGSVY A R
Sbjct: 919 NAIDITQKIGAVNSDQVKGLKATELSWSP-DQNAAAVGTDEGSVYVVTIQDLKIVAAIRT 1095
Query: 463 GSKAGISEMFEGH-----QGPITGIHCH--AAVG------AVDFSHLFVTSSFDWTVKLW 509
K + H Q P CH AA G VD + +F D L
Sbjct: 1096QQK--LINCVRWHPRLTDQSPAGSPCCHWLAAAGNDQVIHVVDLASVFAEREGDKETSLI 1269
Query: 510 TTKNNKPLYSFEDNADYVYDVMWSPTHPALFACVDGMGRLDLWNLNNDTEV 560
T L ++ V D+ WSP H A V +W++ T +
Sbjct: 1270LTS----LRELSGHSQRVTDMSWSPHHDARLVSVGYDAEAFVWDVQKGTAL 1410
>00432
Length = 1557
Score = 32.3 bits (72), Expect = 0.61, Method: Compositional matrix adjust.
Identities = 16/46 (34%), Positives = 23/46 (50%)
Frame = -1
Query: 205 PHELTEEEKQQILHSEEFLSFFDHSTRIVERALSEQINIFFDYSGR 250
PH LT + +Q H E+F + F TRI L + + FF + R
Sbjct: 300 PHALTNQFRQFRFHREKFFTQFIGRTRIFHAILRQFFHAFFGFPNR 163
>27465
Length = 658
Score = 31.6 bits (70), Expect = 0.89, Method: Compositional matrix adjust.
Identities = 25/97 (25%), Positives = 46/97 (47%), Gaps = 6/97 (6%)
Frame = -1
Query: 445 NNFVVGSEEGSVYTACRHGSKAGISEM--FEGHQGPITGIHCHAAVGAVDFSHLF----V 498
++F+ GS + + C+ A E+ EGH+ V A+ F++ F +
Sbjct: 322 SSFITGSYDRT----CKIWDTASAEELHTLEGHRN---------VVYAIAFNNPFGDKVI 182
Query: 499 TSSFDWTVKLWTTKNNKPLYSFEDNADYVYDVMWSPT 535
T SFD T KLW+T + K ++ + + V ++P+
Sbjct: 181 TGSFDKTCKLWSTADGKCYHTLRGHTAEIVCVSFNPS 71
>01768
Length = 1424
Score = 31.2 bits (69), Expect = 1.3, Method: Compositional matrix adjust.
Identities = 24/93 (25%), Positives = 42/93 (45%), Gaps = 2/93 (2%)
Frame = +3
Query: 509 WTTKNNKPLYSFEDNADYVYDVMWSPTHPALFACVDGMGRLDLWNLNND-TEVPTASISV 567
WTT+ + S+ + D V DV WSP +FA L +WN ++ ++
Sbjct: 804 WTTEKS----SYAAHTDSVEDVQWSPNEGNVFASCSVDRTLRIWNTQQKPSKANVLTVPE 971
Query: 568 EGNPALNRVRWTHSGRE-IAVGDSEGQIVIYDV 599
+ +N + W + +A G +G I I+D+
Sbjct: 972 AHSRDINVINWNPIEKHLLASGGDDGIIKIWDL 1070
>26107
Length = 1338
Score = 30.8 bits (68), Expect = 1.7, Method: Compositional matrix adjust.
Identities = 24/95 (25%), Positives = 36/95 (37%), Gaps = 1/95 (1%)
Frame = -3
Query: 274 ERWSKHR-VVSCLDWSSQYPELLVASYNNNEDAPHEPDGVALVWNMKYKKTTPEYVFHCQ 332
RW H V W S + L AS D +W+++ ++ H +
Sbjct: 1105 HRWXAHNNAVFDYSWISNDSQCLTAS----------GDQTVALWDVETTTKVTTFIGH-K 959
Query: 333 SAVMSATFAKFHPNLVVGGTYSGQIVLWDNRSNKR 367
+V S P G G I+LWD+R NK+
Sbjct: 958 CSVRSVASCPSSPAQCASGARDGHIMLWDSRVNKK 854
>06996
Length = 1826
Score = 30.4 bits (67), Expect = 2.1, Method: Compositional matrix adjust.
Identities = 24/88 (27%), Positives = 40/88 (45%)
Frame = -3
Query: 408 CSWSLDMLSHPQDSMELVHKQSKAVAVTSMSFPVGDVNNFVVGSEEGSVYTACRHGSKAG 467
+WS++ S SME++H +V+++ S PV FVVG + YT +H +
Sbjct: 1818 LNWSIE-FSSDLHSMEIIHHFFSSVSISPFSVPV-----FVVG--QPIPYTDLKHKTNTY 1663
Query: 468 ISEMFEGHQGPITGIHCHAAVGAVDFSH 495
++F T H + + FSH
Sbjct: 1662 AKDLFRKEWDKQTDYKLH-EISPILFSH 1582
>37180
Length = 681
Score = 30.4 bits (67), Expect = 2.4, Method: Compositional matrix adjust.
Identities = 30/112 (26%), Positives = 48/112 (42%), Gaps = 6/112 (5%)
Frame = +1
Query: 470 EMFEGHQGPITGIHCHAAVGAVDFSHLFVTSSFDWTVKLWTTKNNKPLYSFEDNADYVYD 529
+ GH ++ +H H L VTSS D T +LW +++ L + V+
Sbjct: 1 NVLNGHDQELSDVHAHPT------QRLVVTSSKDMTFRLWDFRDSALLVN-------VFQ 141
Query: 530 VMWSPTHPALFACVDGM--GRLD----LWNLNNDTEVPTASISVEGNPALNR 575
P A+FA D + G D +W++ N P A+I + A+NR
Sbjct: 142 GHTQPVTSAVFASGDKVVSGSDDRTVRVWDMRN-MRSPIATIRTDS--AVNR 288
>00561
Length = 1003
Score = 30.0 bits (66), Expect = 2.9, Method: Compositional matrix adjust.
Identities = 36/137 (26%), Positives = 58/137 (42%), Gaps = 4/137 (2%)
Frame = -3
Query: 469 SEMFEGHQGPITGIHCHAAVGAVDFSHLFVTSSFDWTVKLWTTKNNKPLYSFED-NADYV 527
+ FEGH + + A + V+ S D T+KLW T ED + D+V
Sbjct: 761 TRRFEGHTKDVLSVAFSAD------NRQIVSGSRDKTIKLWNTLAECKFTIQEDGHTDWV 600
Query: 528 YDVMWSPTH--PALFACVDGMGR-LDLWNLNNDTEVPTASISVEGNPALNRVRWTHSGRE 584
V +SP H P + +C G R + +WNL N + N LN V + G
Sbjct: 599 SCVRFSPNHSNPIIVSC--GWDRTVKVWNLAN---CKLKNNHHGHNGYLNTVTVSPDGSL 435
Query: 585 IAVGDSEGQIVIYDVGE 601
G + + +++D+ +
Sbjct: 434 CTSGGKDSKALLWDLND 384
>12140
Length = 727
Score = 29.3 bits (64), Expect = 4.8, Method: Compositional matrix adjust.
Identities = 23/107 (21%), Positives = 49/107 (45%), Gaps = 6/107 (5%)
Frame = +2
Query: 497 FVTSSFDWTVKLWTTKNNKPL--YSFEDNADYVYDVMWSPT----HPALFACVDGMGRLD 550
FV+ D VK+W + E ++D+V DV W+P+ + +C R+
Sbjct: 269 FVSGGCDNLVKIWREDETGWVEDQKLEGHSDWVRDVAWAPSIGLPRNVIASCSQDC-RVI 445
Query: 551 LWNLNNDTEVPTASISVEGNPALNRVRWTHSGREIAVGDSEGQIVIY 597
+W + + T+ I + + + V W+ +G +AV + ++ ++
Sbjct: 446 IWTNDGSSNQWTSRILNKFSDVVWHVSWSVTGNILAVSGGDNKVTLW 586
>01805
Length = 2124
Score = 29.3 bits (64), Expect = 5.5, Method: Compositional matrix adjust.
Identities = 17/54 (31%), Positives = 30/54 (55%), Gaps = 5/54 (9%)
Frame = -1
Query: 475 HQGPITGIHCHAA-VGAVDFSH----LFVTSSFDWTVKLWTTKNNKPLYSFEDN 523
H+ P+ + H++ V V S L +T+S D T+K+W +++KP + F N
Sbjct: 222 HEKPVFSVGAHSSCVTGVCLSSQIPGLMITTSEDKTMKVWDIQDDKPTHVFSRN 61
>03395
Length = 2795
Score = 28.9 bits (63), Expect = 6.7, Method: Compositional matrix adjust.
Identities = 38/165 (23%), Positives = 60/165 (36%), Gaps = 3/165 (1%)
Frame = +2
Query: 348 VVGGTYSGQIVLWDNRSNKRTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNLISISTDGKI 407
+V G GQ+ +WD + T R L A H + N +S STDG
Sbjct: 41 LVSGGGEGQVRVWDIVKDMLTGKTRGDLVANMKEHKGKVTAIQIHTNDRCCVSASTDGST 220
Query: 408 CSWSLDMLSHPQDSMELVHKQSKAVAVTSMSFPVGDVNNFVVGSEEGSVYTACRHGSKAG 467
W D++++ + + L + K V F D++ G++ Y G G
Sbjct: 221 IIW--DLITNTRSQIVLANTLFKCVC-----FGGKDLHILTSGTDHKIGYWEVGDG---G 370
Query: 468 ISEMFEGHQGPITGIHCHAAVGAVDF---SHLFVTSSFDWTVKLW 509
+ EG Q A+ +D +T D +KLW
Sbjct: 371 LLRELEGSQ--------TGAINTIDIDRDGQTILTGGEDSLLKLW 481
>30429
Length = 674
Score = 28.9 bits (63), Expect = 7.3, Method: Compositional matrix adjust.
Identities = 15/49 (30%), Positives = 23/49 (46%), Gaps = 3/49 (6%)
Frame = -2
Query: 496 LFVTSSFDWTVKLWTTKNNKPLY---SFEDNADYVYDVMWSPTHPALFA 541
+ V FDW +K + N +PL+ SF D +V+ + P L A
Sbjct: 592 VLVKKCFDWKLKQFNNNNKRPLFHHNSFHDGNSHVWLCLCPSPLPNLIA 446
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000263811 | hsapiens_gene_ensembl | Cytoplasmic
dynein 1 intermediate chain 2 (Dynein intermediate chain 2, cytosolic)
(DH IC-2) (Cytoplasmic dynein intermediate chain 2).
[Source:Uniprot/SWISSPROT;Acc:Q13409]
(632 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
20271 294 8e-80
14105 168 5e-42
12841 125 5e-29
07741 55 1e-07
20662 53 3e-07
03387 47 3e-05
08355 47 3e-05
13278 43 3e-04
02960 41 0.001
05393 35 0.13
27475 34 0.15
15972 34 0.16
01598 34 0.18
00432 32 0.60
27465 32 0.86
01768 31 1.3
26107 31 1.8
06996 30 2.0
37180 30 2.4
00561 30 3.2
12140 29 4.6
01805 29 5.2
03395 29 6.1
30429 29 7.1
>20271
Length = 567
Score = 294 bits (752), Expect = 8e-80, Method: Compositional matrix adjust.
Identities = 137/189 (72%), Positives = 157/189 (83%)
Frame = -1
Query: 376 HPVYCVNVVGTQNAHNLISISTDGKICSWSLDMLSHPQDSMELVHKQSKAVAVTSMSFPV 435
HPVYC+ VVGTQNAHNLIS+S DGK+CSWSLDMLS PQDSMEL HKQSK+VA T SF
Sbjct: 567 HPVYCITVVGTQNAHNLISVSNDGKLCSWSLDMLSQPQDSMELQHKQSKSVAATCFSFLS 388
Query: 436 GDVNNFVVGSEEGSVYTACRHGSKAGISEMFEGHQGPITGIHCHAAVGAVDFSHLFVTSS 495
GD NNF+VGSEE VY+A RHGSKAGI+E +EGHQGPIT I H A G +DFS F+T+S
Sbjct: 387 GDANNFIVGSEECLVYSASRHGSKAGINEAYEGHQGPITAIDTHHAAGQIDFSPFFLTAS 208
Query: 496 FDWTVKLWTTKNNKPLYSFEDNADYVYDVMWSPTHPALFACVDGMGRLDLWNLNNDTEVP 555
FDWTVKLW K K + SFEDN+DYV DV WSPT+PALF+CVD MGRLDLW+LN++TEVP
Sbjct: 207 FDWTVKLWNIKEQKYVCSFEDNSDYVSDVQWSPTNPALFSCVDIMGRLDLWHLNHETEVP 28
Query: 556 TASISVEGN 564
TAS+ V+GN
Sbjct: 27 TASVVVDGN 1
>14105
Length = 429
Score = 168 bits (426), Expect = 5e-42, Method: Compositional matrix adjust.
Identities = 75/111 (67%), Positives = 87/111 (78%)
Frame = +3
Query: 502 LWTTKNNKPLYSFEDNADYVYDVMWSPTHPALFACVDGMGRLDLWNLNNDTEVPTASISV 561
LW+ K+ KPLYSFEDN+DYV DV WSP HPALFA VDG GRLDLWNLN DTEVPTASI V
Sbjct: 3 LWSLKDTKPLYSFEDNSDYVMDVAWSPVHPALFAAVDGSGRLDLWNLNQDTEVPTASIVV 182
Query: 562 EGNPALNRVRWTHSGREIAVGDSEGQIVIYDVGEQIAVPRNDEWARFGRTL 612
+G PALNRV WT SG + +GD G++ +YDV E +A+P DEW+RF TL
Sbjct: 183 DGAPALNRVSWTPSGLHVTIGDESGKLYVYDVAEHLALPTRDEWSRFNATL 335
>12841
Length = 1364
Score = 125 bits (314), Expect = 5e-29, Method: Compositional matrix adjust.
Identities = 90/333 (27%), Positives = 144/333 (43%), Gaps = 28/333 (8%)
Frame = +1
Query: 266 FDERWS------KHRVVSCLDWSSQYPELLVASYNNNEDAPHEPDGVALVWNMKYKKTTP 319
D WS K R VSCL W+ P+L+ Y D ++ G+ W++K P
Sbjct: 361 LDRLWSYVCPLTKGRNVSCLAWNKSNPDLVAVGYGQF-DFTNQKSGLICCWSLK-NPEYP 534
Query: 320 EYVFHCQSAVMSATFAKFHPNLVVGGTYSGQIVLWDNRSNKRTPVQRTPLSAAAHTHPVY 379
E V+ V S F+ + N++ G Y G + +++ RS P+ + H PV+
Sbjct: 535 ERVYTSTHGVTSLDFSVANANILAAGYYDGGVAIYNVRSTSDEPILDNQETHGKHLGPVW 714
Query: 380 CVNVV------GTQNAHNLISISTDGKICSWSLDMLSHPQDSMELVH---------KQSK 424
+ + G + A LISISTDG++ WS+ + M L ++ K
Sbjct: 715 QIQWIEKERGSGEERAEVLISISTDGRVTQWSIRKGFESNNIMRLKKLPTRMAGKAREKK 894
Query: 425 AVAVTS-------MSFPVGDVNNFVVGSEEGSVYTACRHGSKAGISEMFEGHQGPITGIH 477
A S F D+N ++ G+EEG ++ C E + GH P+ I
Sbjct: 895 GEAFISRHAGGLCFDFHSRDLNVYLAGTEEGYIH-KCSCSYNEQYLETYSGHTAPVYHIR 1071
Query: 478 CHAAVGAVDFSHLFVTSSFDWTVKLWTTKNNKPLYSFEDNADYVYDVMWSPTHPALFACV 537
V S +F++ S DW+++LW P+ +F + V+DV WSP +FACV
Sbjct: 1072WSPFV-----SDIFLSCSADWSIRLWHQDRTTPILTFHSSTKTVHDVCWSPRSSTVFACV 1236
Query: 538 DGMGRLDLWNLNNDTEVPTASISVEGNPALNRV 570
G +++W+L T +I+ L V
Sbjct: 1237H-EGAVEVWDLAQSTLDAVITITPTSGAKLTSV 1332
>07741
Length = 2119
Score = 54.7 bits (130), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 43/165 (26%), Positives = 76/165 (46%), Gaps = 17/165 (10%)
Frame = +1
Query: 441 FVVGSEEGSVYTACRHGSKAGISEMFEGHQGPITGIHCHAAVGAVDFSH----LFVTSSF 496
F+VG+EEG V+ C + + + H + AV V ++H ++ T S
Sbjct: 157 FLVGTEEGKVH-VCSKAYTSHFIDTLDSH---------NMAVYKVAWNHYHPKIYATCSA 306
Query: 497 DWTVKLW-----------TTKNNKPLYSFEDNADYVYDVMWSPTHPALFACVDGMGRLDL 545
DW VK+W + + KPL+SF+ N + V DV W+P +FA V G++ +
Sbjct: 307 DWNVKIWENGGKPTDTGXDSLSRKPLFSFDLN-NSVGDVAWAPYSSTVFAAVTADGKVCV 483
Query: 546 WNLNNDTEVPTAS--ISVEGNPALNRVRWTHSGREIAVGDSEGQI 588
++L+ + P ++ + L + + S + VGD G +
Sbjct: 484 YDLSVNKYEPLCEQMVAQKKKTKLTHIEFNPSYPILIVGDDRGNV 618
Score = 29.6 bits (65), Expect = 4.1, Method: Compositional matrix adjust.
Identities = 20/81 (24%), Positives = 37/81 (45%), Gaps = 8/81 (9%)
Frame = +1
Query: 521 VYDVMWSPTHPALFACVDGMGRLDLW-NLNNDTEVPTASI------SVEGNPALNRVRWT 573
VY V W+ HP ++A + +W N T+ S+ S + N ++ V W
Sbjct: 250 VYKVAWNHYHPKIYATCSADWNVKIWENGGKPTDTGXDSLSRKPLFSFDLNNSVGDVAWA 429
Query: 574 -HSGREIAVGDSEGQIVIYDV 593
+S A ++G++ +YD+
Sbjct: 430 PYSSTVFAAVTADGKVCVYDL 492
>20662
Length = 1220
Score = 53.1 bits (126), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 39/131 (29%), Positives = 69/131 (52%), Gaps = 4/131 (3%)
Frame = +2
Query: 486 DFSHLFVTSSFDWTVKLWTTKNNKPLYSFEDNADYVYDVMWSPTHPALFACVDGMGRLDL 545
D SH ++++S+D +K+W T + LY++ ++D V+DV PT PALF G++ L
Sbjct: 419 DXSH-YLSASYDHGIKVWNT-DLTSLYTYRAHSDIVWDVQCHPTEPALFLSCSQDGKIVL 592
Query: 546 WNLNND---TEVPTASISVEGNPALNRVRWTHSGREI-AVGDSEGQIVIYDVGEQIAVPR 601
W++ T +P S + P V+W + R + AVGD G + + D+ ++ V +
Sbjct: 593 WDVRESKPATCLPKCSSGFK--PTC--VQWQPNARNMYAVGDEGGHVSVQDL--RMVVEK 754
Query: 602 NDEWARFGRTL 612
N + R +
Sbjct: 755 NVSYQSHNRVV 787
>03387
Length = 1891
Score = 46.6 bits (109), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 61/265 (23%), Positives = 107/265 (40%), Gaps = 13/265 (4%)
Frame = +1
Query: 326 QSAVMSATFAKFHPNLVVGGTYSGQIVLWDNRSNKRTP---VQRTP-LSAAAHTHPVYCV 381
+ V A + +P ++ T S ++++D + P + P L H Y +
Sbjct: 202 EGEVNRARYMPQNPCIIATKTPSSDVLVFDYTKHPSKPDPSGECIPELRLKGHQKEGYGL 381
Query: 382 NVVGTQNAHNLISISTDGKICSWSLDMLSHPQDSMELVHKQSKAVAVTSMSFPVGDVNNF 441
+ N H L+S S D IC W ++ Q +V + TS+ V DV
Sbjct: 382 SWNPNLNGH-LLSASDDHTICLWDINST---QRESRVVDAHTIFTGHTSV---VEDVAWH 540
Query: 442 V--------VGSEEGSVYTACRHGSKAGISEMFEGHQGPITGIHCHAAVGAVDFSHLFVT 493
+ V ++ + R + + S + + H + C + +F + T
Sbjct: 541 LLHESLFGSVADDQKLMIWDTRSNTTSKPSHVVDAHTAEVN---CLSFNPYSEF--ILAT 705
Query: 494 SSFDWTVKLWTTKNNK-PLYSFEDNADYVYDVMWSPTHPALFACVDGMGRLDLWNLNNDT 552
S D TV LW +N K L+SFE + D ++ V WSP + + A RL +W+L+
Sbjct: 706 GSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLHVWDLSKIG 885
Query: 553 EVPTASISVEGNPALNRVRWTHSGR 577
E + +G P L + H+ +
Sbjct: 886 EEQLPEDAEDGPPELLFIHGGHTAK 960
>08355
Length = 498
Score = 46.6 bits (109), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 47/173 (27%), Positives = 71/173 (41%), Gaps = 16/173 (9%)
Frame = -1
Query: 347 YSGQIVLWDNRSNKRTPVQRTPLSAAAHTHPVYCVNVV--GTQNAHNLISISTDGKICSW 404
Y G + L++ PVQR HT PV+ V + N N SIS+DG+I W
Sbjct: 495 YDGSVALFNTIEKHNNPVQRCTADNGKHTDPVWQVRWQKDDSDNNMNFFSISSDGRIVHW 316
Query: 405 SL---DMLSHPQDSMELVHKQSKAVAVTSMSFPVGDVNN-----------FVVGSEEGSV 450
++ +M+ QD ++L A + V F+VG+EEG +
Sbjct: 315 TIVKNEMIY--QDIIQLTIPGPPAEGPDGIRMEVTGCGTAFDFHKHKDYLFLVGTEEGKM 142
Query: 451 YTACRHGSKAGISEMFEGHQGPITGIHCHAAVGAVDFSHLFVTSSFDWTVKLW 503
+ SKA S F G G + + +++ T S DW VK+W
Sbjct: 141 HVC----SKAYTSH-FIG-SGDAHNMAIYKVAWNRFHPNVYATCSADWNVKIW 1
>13278
Length = 870
Score = 43.1 bits (100), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 29/110 (26%), Positives = 51/110 (46%), Gaps = 4/110 (3%)
Frame = +1
Query: 488 SHLFVTSSFDWTVKLWTTKNNKPLYSFEDNADYVYDVMWSPTHPALFACVDGMGRLD--- 544
S + ++SFD TV+LW + L++ + + VY V +SP L + G D
Sbjct: 112 SLILASASFDSTVRLWEVERGLCLHTLTKHQEPVYSVAFSPDGKYLAS-----GSFDKCV 276
Query: 545 -LWNLNNDTEVPTASISVEGNPALNRVRWTHSGREIAVGDSEGQIVIYDV 593
+WN+ + V S +G + V W H G ++ S+G + + D+
Sbjct: 277 HIWNVQTGSLVH----SYKGTGGIFEVCWNHRGDKVGASASDGSVFVLDL 414
>02960
Length = 1577
Score = 40.8 bits (94), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 65/265 (24%), Positives = 100/265 (37%), Gaps = 30/265 (11%)
Frame = +2
Query: 304 DGVALVWNMKYKKTTPEYVFHCQSAVMSATFAKFHPN--LVVGGTYSGQIVLWDNRSN-- 359
D ALVW + + + C+ S P+ + G++ + LW N
Sbjct: 680 DQTALVWQWQRETNEVDCRLSCRGHAASVDCVAVSPDSQQMCTGSWDKMLKLWSTDCNVD 859
Query: 360 -----------------KRTPVQRTP-LSAAAHTHPVYCVNVVGTQNAHNLISISTDGKI 401
K T R P L+ + H V V + + H +++ S D +
Sbjct: 860 GDQSEDTERPSKKKKSAKSTTQTRVPVLTLSGHAEAVSAVRWL---DPHRVVTSSWDHSL 1030
Query: 402 CSWSLDMLSHPQDSMELVHKQSKAVAVTSMSFPVGDVNNFVVGSEEGSVYTA---CRHGS 458
W L H L+ + SKAV + S P+ + + GS + V C G
Sbjct: 1031RLWDL----HTAQQTSLI-QGSKAVLDVAYS-PLS--HMLITGSADRHVRLVDPRCSEGE 1186
Query: 459 KAGISEMFEGHQGPITGIHCHAAVGAVDFS----HLFVTSSFDWTVKLWTTKNNKP-LYS 513
+ F H G +TG VD+S HLF++ S+D +KLW T++ K LY
Sbjct: 1187TVKCA--FTSHTGWVTG---------VDWSPTREHLFLSGSYDNVLKLWDTRSPKATLYD 1333
Query: 514 FEDNADYVYDVMWSPTHPALFACVD 538
+ D + V WS L VD
Sbjct: 1334MNWHEDRILAVDWSIPELLLSGGVD 1408
>05393
Length = 904
Score = 34.7 bits (78), Expect = 0.13, Method: Compositional matrix adjust.
Identities = 24/93 (25%), Positives = 42/93 (45%), Gaps = 7/93 (7%)
Frame = +1
Query: 469 HQGPITGIHCHA-AVGAVDFSH----LFVTSSFDWTVKLWTTKNNKPLYSFEDNADY--V 521
H+ P+ + H+ V V S L +T+S D T+K+W +++KP + F N +
Sbjct: 187 HEKPVFSVGAHSSCVTGVCLSSQIPGLMITTSEDKTMKVWDIQDDKPTHVFSRNLKMKEL 366
Query: 522 YDVMWSPTHPALFACVDGMGRLDLWNLNNDTEV 554
+ P P +FA G +W++ V
Sbjct: 367 HCTGCCPEAPFVFAVGGGRREPKVWDIRESAAV 465
>27475
Length = 369
Score = 34.3 bits (77), Expect = 0.15, Method: Compositional matrix adjust.
Identities = 27/78 (34%), Positives = 37/78 (47%), Gaps = 5/78 (6%)
Frame = +2
Query: 466 FEGHQGPITGIHCHAAVGAVDFS----HLFVTSSFDWTVKLWTTKNNKP-LYSFEDNADY 520
F H G +TG VD+S HLF++ S+D +KLW T++ K LY + D
Sbjct: 56 FTSHTGWVTG---------VDWSPTREHLFLSGSYDNVLKLWDTRSPKATLYDMNWHEDR 208
Query: 521 VYDVMWSPTHPALFACVD 538
+ V WS L VD
Sbjct: 209 ILAVDWSIPELLLSGGVD 262
>15972
Length = 1069
Score = 34.3 bits (77), Expect = 0.16, Method: Compositional matrix adjust.
Identities = 21/83 (25%), Positives = 38/83 (45%)
Frame = +3
Query: 466 FEGHQGPITGIHCHAAVGAVDFSHLFVTSSFDWTVKLWTTKNNKPLYSFEDNADYVYDVM 525
F GH+GP+ + H + L +T S D T++LW N + + + + V
Sbjct: 225 FSGHKGPVRHLAVHPS------GKLTLTVSQDRTLRLWNNMNGRIAF-ISNMKEAAESVR 383
Query: 526 WSPTHPALFACVDGMGRLDLWNL 548
W+P L+ V LD++++
Sbjct: 384 WAP--GGLYYVVAFRSHLDVYSV 446
>01598
Length = 1545
Score = 33.9 bits (76), Expect = 0.18, Method: Compositional matrix adjust.
Identities = 29/109 (26%), Positives = 46/109 (42%), Gaps = 3/109 (2%)
Frame = +1
Query: 488 SHLFVTSSFDWTVKLWTTKNNKPLYSFEDNADYVYDVMWSPTHPALFACVDGMGRLDLWN 547
S T + D V LW + + + S +VY V SP P A G + WN
Sbjct: 415 SKTLCTFAQDRQVVLWDLETMEAVASMATLGGHVYCVRTSPIDPGRVAVGVGDSMIRTWN 594
Query: 548 LNNDTEVPTASISVEG-NPALNRVRWTHSGRE--IAVGDSEGQIVIYDV 593
++N T + +G + V W H +E + G +G+I ++DV
Sbjct: 595 MSNKTNPYDVTTLWQGIKSKVTAVAW-HPTKEGWLGFGTDDGRIGVFDV 738
Score = 29.6 bits (65), Expect = 3.8, Method: Compositional matrix adjust.
Identities = 70/291 (24%), Positives = 105/291 (36%), Gaps = 40/291 (13%)
Frame = +1
Query: 304 DGVALVWNMKYKKTTPEYVFHCQSAVMSATFAKFHP---NLVVGGTYSGQIVLWDNRSNK 360
D + WNM K + Q T +HP + GT G+I ++D S+K
Sbjct: 571 DSMIRTWNMSNKTNPYDVTTLWQGIKSKVTAVAWHPTKEGWLGFGTDDGRIGVFDVLSHK 750
Query: 361 RTPVQRTPLSAAAHTHPVYCVNVVGTQ----NAHNLISISTDGKICSWSLDMLSHPQ--- 413
+ T A+ V C + +L S+ D KI S +LS +
Sbjct: 751 MPTLSNTFHHRTAY---VVCWGPASLSPTDGKSFSLYSVG-DCKILEHSSAVLSRGEKKA 918
Query: 414 DSMELVHK-------QSKAVAVTSMSFPVGDVNNFVVGSEEGSVYT----------ACRH 456
+++++ K Q K + T +S+ D N VG++EGSVY A R
Sbjct: 919 NAIDITQKIGAVNSDQVKGLKATELSWSP-DQNAAAVGTDEGSVYVVTIQDLKIVAAIRT 1095
Query: 457 GSKAGISEMFEGH-----QGPITGIHCH--AAVG------AVDFSHLFVTSSFDWTVKLW 503
K + H Q P CH AA G VD + +F D L
Sbjct: 1096QQK--LINCVRWHPRLTDQSPAGSPCCHWLAAAGNDQVIHVVDLASVFAEREGDKETSLI 1269
Query: 504 TTKNNKPLYSFEDNADYVYDVMWSPTHPALFACVDGMGRLDLWNLNNDTEV 554
T L ++ V D+ WSP H A V +W++ T +
Sbjct: 1270LTS----LRELSGHSQRVTDMSWSPHHDARLVSVGYDAEAFVWDVQKGTAL 1410
>00432
Length = 1557
Score = 32.3 bits (72), Expect = 0.60, Method: Compositional matrix adjust.
Identities = 16/46 (34%), Positives = 23/46 (50%)
Frame = -1
Query: 199 PHELTEEEKQQILHSEEFLSFFDHSTRIVERALSEQINIFFDYSGR 244
PH LT + +Q H E+F + F TRI L + + FF + R
Sbjct: 300 PHALTNQFRQFRFHREKFFTQFIGRTRIFHAILRQFFHAFFGFPNR 163
>27465
Length = 658
Score = 32.0 bits (71), Expect = 0.86, Method: Compositional matrix adjust.
Identities = 25/97 (25%), Positives = 46/97 (47%), Gaps = 6/97 (6%)
Frame = -1
Query: 439 NNFVVGSEEGSVYTACRHGSKAGISEM--FEGHQGPITGIHCHAAVGAVDFSHLF----V 492
++F+ GS + + C+ A E+ EGH+ V A+ F++ F +
Sbjct: 322 SSFITGSYDRT----CKIWDTASAEELHTLEGHRN---------VVYAIAFNNPFGDKVI 182
Query: 493 TSSFDWTVKLWTTKNNKPLYSFEDNADYVYDVMWSPT 529
T SFD T KLW+T + K ++ + + V ++P+
Sbjct: 181 TGSFDKTCKLWSTADGKCYHTLRGHTAEIVCVSFNPS 71
>01768
Length = 1424
Score = 31.2 bits (69), Expect = 1.3, Method: Compositional matrix adjust.
Identities = 24/93 (25%), Positives = 42/93 (45%), Gaps = 2/93 (2%)
Frame = +3
Query: 503 WTTKNNKPLYSFEDNADYVYDVMWSPTHPALFACVDGMGRLDLWNLNND-TEVPTASISV 561
WTT+ + S+ + D V DV WSP +FA L +WN ++ ++
Sbjct: 804 WTTEKS----SYAAHTDSVEDVQWSPNEGNVFASCSVDRTLRIWNTQQKPSKANVLTVPE 971
Query: 562 EGNPALNRVRWTHSGRE-IAVGDSEGQIVIYDV 593
+ +N + W + +A G +G I I+D+
Sbjct: 972 AHSRDINVINWNPIEKHLLASGGDDGIIKIWDL 1070
>26107
Length = 1338
Score = 30.8 bits (68), Expect = 1.8, Method: Compositional matrix adjust.
Identities = 24/95 (25%), Positives = 36/95 (37%), Gaps = 1/95 (1%)
Frame = -3
Query: 268 ERWSKHR-VVSCLDWSSQYPELLVASYNNNEDAPHEPDGVALVWNMKYKKTTPEYVFHCQ 326
RW H V W S + L AS D +W+++ ++ H +
Sbjct: 1105 HRWXAHNNAVFDYSWISNDSQCLTAS----------GDQTVALWDVETTTKVTTFIGH-K 959
Query: 327 SAVMSATFAKFHPNLVVGGTYSGQIVLWDNRSNKR 361
+V S P G G I+LWD+R NK+
Sbjct: 958 CSVRSVASCPSSPAQCASGARDGHIMLWDSRVNKK 854
>06996
Length = 1826
Score = 30.4 bits (67), Expect = 2.0, Method: Compositional matrix adjust.
Identities = 24/88 (27%), Positives = 40/88 (45%)
Frame = -3
Query: 402 CSWSLDMLSHPQDSMELVHKQSKAVAVTSMSFPVGDVNNFVVGSEEGSVYTACRHGSKAG 461
+WS++ S SME++H +V+++ S PV FVVG + YT +H +
Sbjct: 1818 LNWSIE-FSSDLHSMEIIHHFFSSVSISPFSVPV-----FVVG--QPIPYTDLKHKTNTY 1663
Query: 462 ISEMFEGHQGPITGIHCHAAVGAVDFSH 489
++F T H + + FSH
Sbjct: 1662 AKDLFRKEWDKQTDYKLH-EISPILFSH 1582
>37180
Length = 681
Score = 30.4 bits (67), Expect = 2.4, Method: Compositional matrix adjust.
Identities = 30/112 (26%), Positives = 48/112 (42%), Gaps = 6/112 (5%)
Frame = +1
Query: 464 EMFEGHQGPITGIHCHAAVGAVDFSHLFVTSSFDWTVKLWTTKNNKPLYSFEDNADYVYD 523
+ GH ++ +H H L VTSS D T +LW +++ L + V+
Sbjct: 1 NVLNGHDQELSDVHAHPT------QRLVVTSSKDMTFRLWDFRDSALLVN-------VFQ 141
Query: 524 VMWSPTHPALFACVDGM--GRLD----LWNLNNDTEVPTASISVEGNPALNR 569
P A+FA D + G D +W++ N P A+I + A+NR
Sbjct: 142 GHTQPVTSAVFASGDKVVSGSDDRTVRVWDMRN-MRSPIATIRTDS--AVNR 288
>00561
Length = 1003
Score = 30.0 bits (66), Expect = 3.2, Method: Compositional matrix adjust.
Identities = 36/137 (26%), Positives = 58/137 (42%), Gaps = 4/137 (2%)
Frame = -3
Query: 463 SEMFEGHQGPITGIHCHAAVGAVDFSHLFVTSSFDWTVKLWTTKNNKPLYSFED-NADYV 521
+ FEGH + + A + V+ S D T+KLW T ED + D+V
Sbjct: 761 TRRFEGHTKDVLSVAFSAD------NRQIVSGSRDKTIKLWNTLAECKFTIQEDGHTDWV 600
Query: 522 YDVMWSPTH--PALFACVDGMGR-LDLWNLNNDTEVPTASISVEGNPALNRVRWTHSGRE 578
V +SP H P + +C G R + +WNL N + N LN V + G
Sbjct: 599 SCVRFSPNHSNPIIVSC--GWDRTVKVWNLAN---CKLKNNHHGHNGYLNTVTVSPDGSL 435
Query: 579 IAVGDSEGQIVIYDVGE 595
G + + +++D+ +
Sbjct: 434 CTSGGKDSKALLWDLND 384
>12140
Length = 727
Score = 29.3 bits (64), Expect = 4.6, Method: Compositional matrix adjust.
Identities = 23/107 (21%), Positives = 49/107 (45%), Gaps = 6/107 (5%)
Frame = +2
Query: 491 FVTSSFDWTVKLWTTKNNKPL--YSFEDNADYVYDVMWSPT----HPALFACVDGMGRLD 544
FV+ D VK+W + E ++D+V DV W+P+ + +C R+
Sbjct: 269 FVSGGCDNLVKIWREDETGWVEDQKLEGHSDWVRDVAWAPSIGLPRNVIASCSQDC-RVI 445
Query: 545 LWNLNNDTEVPTASISVEGNPALNRVRWTHSGREIAVGDSEGQIVIY 591
+W + + T+ I + + + V W+ +G +AV + ++ ++
Sbjct: 446 IWTNDGSSNQWTSRILNKFSDVVWHVSWSVTGNILAVSGGDNKVTLW 586
>01805
Length = 2124
Score = 29.3 bits (64), Expect = 5.2, Method: Compositional matrix adjust.
Identities = 17/54 (31%), Positives = 30/54 (55%), Gaps = 5/54 (9%)
Frame = -1
Query: 469 HQGPITGIHCHAA-VGAVDFSH----LFVTSSFDWTVKLWTTKNNKPLYSFEDN 517
H+ P+ + H++ V V S L +T+S D T+K+W +++KP + F N
Sbjct: 222 HEKPVFSVGAHSSCVTGVCLSSQIPGLMITTSEDKTMKVWDIQDDKPTHVFSRN 61
>03395
Length = 2795
Score = 28.9 bits (63), Expect = 6.1, Method: Compositional matrix adjust.
Identities = 38/165 (23%), Positives = 60/165 (36%), Gaps = 3/165 (1%)
Frame = +2
Query: 342 VVGGTYSGQIVLWDNRSNKRTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNLISISTDGKI 401
+V G GQ+ +WD + T R L A H + N +S STDG
Sbjct: 41 LVSGGGEGQVRVWDIVKDMLTGKTRGDLVANMKEHKGKVTAIQIHTNDRCCVSASTDGST 220
Query: 402 CSWSLDMLSHPQDSMELVHKQSKAVAVTSMSFPVGDVNNFVVGSEEGSVYTACRHGSKAG 461
W D++++ + + L + K V F D++ G++ Y G G
Sbjct: 221 IIW--DLITNTRSQIVLANTLFKCVC-----FGGKDLHILTSGTDHKIGYWEVGDG---G 370
Query: 462 ISEMFEGHQGPITGIHCHAAVGAVDF---SHLFVTSSFDWTVKLW 503
+ EG Q A+ +D +T D +KLW
Sbjct: 371 LLRELEGSQ--------TGAINTIDIDRDGQTILTGGEDSLLKLW 481
>30429
Length = 674
Score = 28.9 bits (63), Expect = 7.1, Method: Compositional matrix adjust.
Identities = 15/49 (30%), Positives = 23/49 (46%), Gaps = 3/49 (6%)
Frame = -2
Query: 490 LFVTSSFDWTVKLWTTKNNKPLY---SFEDNADYVYDVMWSPTHPALFA 535
+ V FDW +K + N +PL+ SF D +V+ + P L A
Sbjct: 592 VLVKKCFDWKLKQFNNNNKRPLFHHNSFHDGNSHVWLCLCPSPLPNLIA 446
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000258198 | hsapiens_gene_ensembl | Cytoplasmic
dynein 1 light intermediate chain 2 (Dynein light intermediate chain
2, cytosolic) (LIC53/55) (LIC-2).
[Source:Uniprot/SWISSPROT;Acc:O43237]
(492 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
06254 275 3e-79
30505 33 0.19
19777 30 1.6
>06254
Length = 2204
Score = 275 bits (703), Expect(2) = 3e-79, Method: Compositional matrix adjust.
Identities = 135/216 (62%), Positives = 171/216 (79%), Gaps = 8/216 (3%)
Frame = +2
Query: 166 PPEKMRELERKFVKDFQDYMEPEEGCQGSPQR--RG---PLTSG--SDEENVALPLGDNV 218
P +KMR+ E+ V+ FQDY PEEG Q S Q RG PL +D++ V LPLGDNV
Sbjct: 215 PQKKMRDYEQSLVRFFQDYTAPEEG-QSSSQAPPRGDANPLHPALMTDDDKVVLPLGDNV 391
Query: 219 LTHNLGIPVLVVCTKCDAVSVLEKEHDYRDEHLDFIQSHLRRFCLQYGAALIYTSVKEEK 278
LTHNLGIPV+VV TKCDA+S LEK+HD+R+EH DFIQ ++R+FCL+YGA L YTSVK+E+
Sbjct: 392 LTHNLGIPVVVVLTKCDAISSLEKDHDFREEHFDFIQQYVRKFCLKYGAGLFYTSVKDER 571
Query: 279 NLDLLYKYIVHKTYGFHFTTPALVVEKDAVFIPAGWDNEKKIAILHENFTTVKPEDAYED 338
N +LLY+Y+VH+ YGF FTTPA VV++D+VF+P GWDNEKKI+IL+EN ++VKPED ED
Sbjct: 572 NCELLYRYLVHRIYGFPFTTPAYVVDRDSVFVPCGWDNEKKISILYENMSSVKPEDGLED 751
Query: 339 FIVKPPVRKLVH-DKELAAEDEQVFLMKQQSLLAKQ 373
IV+P +RK V D E+ AEDEQV+LMK Q++LAKQ
Sbjct: 752 VIVRPVLRKPVQRDAEVFAEDEQVYLMKLQAVLAKQ 859
Score = 38.9 bits (89), Expect(2) = 3e-79, Method: Compositional matrix adjust.
Identities = 14/31 (45%), Positives = 22/31 (70%)
Frame = +3
Query: 98 RDDHTRCNVWILDGDLYHKGLLKFAVSAESL 128
RD+ R NVW+LDGD H L+K+A++ ++
Sbjct: 9 RDEQARLNVWVLDGDQSHTALMKYALTEDNF 101
Score = 58.2 bits (139), Expect = 7e-09, Method: Compositional matrix adjust.
Identities = 23/48 (47%), Positives = 36/48 (75%)
Frame = +1
Query: 130 ETLVIFVADMSRPWTVMESLQKWASVLREHIDKMKIPPEKMRELERKF 177
+++V+ VA M++PW++ +SL KW +VL +HIDK++IPPEK L K
Sbjct: 106 DSMVMLVASMAQPWSIADSLTKWITVLSQHIDKLRIPPEKNERLXTKL 249
Score = 38.9 bits (89), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 16/21 (76%), Positives = 21/21 (100%)
Frame = +1
Query: 424 ASEGVLASFFNSLLSKKTGSP 444
A+EG+LA+FFNSLL+KKTG+P
Sbjct: 1012 ATEGMLANFFNSLLNKKTGAP 1074
>30505
Length = 549
Score = 33.5 bits (75), Expect = 0.19, Method: Compositional matrix adjust.
Identities = 16/62 (25%), Positives = 29/62 (46%)
Frame = +3
Query: 36 WSSILSEVSTRARSKLPSGKNILVFGEDGSGKTTLMTKLQGAEHGKKGRGLEYLYLSVHD 95
++ +++ R + +G ILV G+ G+GK+ L L G + GR ++H
Sbjct: 255 FAGLMATTGDEERGRTDNGHRILVIGKAGNGKSALCNALTGTQQFPTGRSFAATTRTMHS 434
Query: 96 ED 97
D
Sbjct: 435 FD 440
>19777
Length = 671
Score = 30.4 bits (67), Expect = 1.6, Method: Compositional matrix adjust.
Identities = 15/34 (44%), Positives = 20/34 (58%)
Frame = -1
Query: 50 KLPSGKNILVFGEDGSGKTTLMTKLQGAEHGKKG 83
KL SG +ILV G+ G GKT+L+ + G G
Sbjct: 569 KLHSGTSILVTGDSGCGKTSLLRVIAGLWKSSTG 468
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000373225 | hsapiens_gene_ensembl | sarcolemma
associated protein [Source:RefSeq_peptide;Acc:NP_009090]
(428 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
14682 267 4e-79
14883 40 0.002
08467 28 5.0
09375 28 5.2
18219 28 7.8
>14682
Length = 1076
Score = 267 bits (683), Expect(2) = 4e-79, Method: Compositional matrix adjust.
Identities = 138/236 (58%), Positives = 181/236 (76%), Gaps = 3/236 (1%)
Frame = -1
Query: 90 EESPPCEILSGDIIQFGVDVTENTR---KVTHGCIVSTIKLFLPDGMEARLRSDVIHAPL 146
EESP E+ SGD+IQFGV+V EN R K+THGCI++T+ L+ PDG EA+ P+
Sbjct: 1076 EESPMREVYSGDLIQFGVEVMENNRRGEKITHGCIIATLTLYHPDGREAK--------PV 921
Query: 147 PSPVDKVAANTPSMYSQELFQLSQYLQEALHREQMLEQKLATLQRLLAITQEASDTSWQA 206
P D T ++ SQ+L+QL+ +LQEALHRE+MLEQKL +LQ+L+ TQEA++ WQA
Sbjct: 920 PFLSDPNQPGT-TIQSQDLYQLAHFLQEALHREKMLEQKLGSLQQLVHXTQEAAEGGWQA 744
Query: 207 LIDEDRLLSRLEVMGNQLQACSKNQTEDSLRKELIALQEDKHNYETTAKESLRRVLQEKI 266
LIDED+LLSRLE++ NQL SKN +EDSLR+EL+ALQEDK NYETTAKESLRRVLQEK+
Sbjct: 743 LIDEDKLLSRLEMLENQLHIYSKNHSEDSLRQELVALQEDKINYETTAKESLRRVLQEKL 564
Query: 267 EVVRKLSEVERSLSNTEDECTHLKEMNERTQEELRELANKYNGAVNEIKDLSDKLK 322
+ V KLS++ERSL++ E EC HLKEM E +QEEL++LA +Y + E+ +L +KL+
Sbjct: 563 DAVTKLSDLERSLTSAEGECNHLKEMCESSQEELKQLATRYQDQLKEVMELQEKLQ 396
Score = 45.8 bits (107), Expect(2) = 4e-79, Method: Compositional matrix adjust.
Identities = 24/54 (44%), Positives = 37/54 (68%)
Frame = -3
Query: 342 LQHKIDEMEEKEQELQAKIEALQADNDFTNERLTALQVRLEHLQEKTLKECSSL 395
L K+++M ++E L AKIE+LQADNDF E+L A++ +LE +E +E +L
Sbjct: 339 LMEKLEDMIQQESSLSAKIESLQADNDFAREQLAAMKAKLESKKETNQEEDKAL 178
>14883
Length = 954
Score = 39.7 bits (91), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 19/37 (51%), Positives = 28/37 (75%)
Frame = -3
Query: 342 LQHKIDEMEEKEQELQAKIEALQADNDFTNERLTALQ 378
L K+++M ++E L AKIE+LQADNDF E+L A++
Sbjct: 856 LMEKLEDMIQQESSLSAKIESLQADNDFAREQLAAMK 746
>08467
Length = 1621
Score = 28.5 bits (62), Expect = 5.0, Method: Compositional matrix adjust.
Identities = 15/58 (25%), Positives = 29/58 (50%)
Frame = -3
Query: 209 DEDRLLSRLEVMGNQLQACSKNQTEDSLRKELIALQEDKHNYETTAKESLRRVLQEKI 266
+ED+ V+ N + + +T + + L + KH+YE TA + LR +Q ++
Sbjct: 932 NEDKAEIDF*VINNLQEGIKRMRTRTHVHTHITLLFKPKHSYEATANQPLRYFVQSRL 759
>09375
Length = 1361
Score = 28.5 bits (62), Expect = 5.2, Method: Compositional matrix adjust.
Identities = 25/93 (26%), Positives = 42/93 (45%)
Frame = -2
Query: 203 SWQALIDEDRLLSRLEVMGNQLQACSKNQTEDSLRKELIALQEDKHNYETTAKESLRRVL 262
SW+ D L+S ++ QLQ LRK++ + + N +T A LR +
Sbjct: 574 SWKTY--NDTLVSMIDSAQKQLQ---------DLRKKIQEINWQRKNEQTQAGTKLRELE 428
Query: 263 QEKIEVVRKLSEVERSLSNTEDECTHLKEMNER 295
+ +V K E+ER+ E E ++E N +
Sbjct: 427 TSWVGLVSKNYEIERACVELEKEVAEMEERNAK 329
>18219
Length = 476
Score = 28.1 bits (61), Expect = 7.8, Method: Compositional matrix adjust.
Identities = 22/81 (27%), Positives = 41/81 (50%), Gaps = 8/81 (9%)
Frame = -2
Query: 191 RLLAITQEASDTSWQALIDEDRLLSRLEVMGNQLQACSKNQTEDSL--------RKELIA 242
RLL Q+ +D S ++DE+ LL+ ++++G C + + E SL R+EL+
Sbjct: 448 RLLPDKQDKNDNSCVNMVDEEPLLAVIKIVG-----CPEVEPEMSLYLRVCSTCREELVQ 284
Query: 243 LQEDKHNYETTAKESLRRVLQ 263
Q ++ E A + +L+
Sbjct: 283 RQVERTQEEDGAPTGMDMMLE 221
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000295951 | hsapiens_gene_ensembl | sarcolemma
associated protein [Source:RefSeq_peptide;Acc:NP_009090]
(811 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
14682 268 4e-78
14883 40 0.003
08467 29 6.8
17475 29 9.5
>14682
Length = 1076
Score = 268 bits (685), Expect(2) = 4e-78, Method: Compositional matrix adjust.
Identities = 138/236 (58%), Positives = 181/236 (76%), Gaps = 3/236 (1%)
Frame = -1
Query: 90 EESPPCEILSGDIIQFGVDVTENTR---KVTHGCIVSTIKLFLPDGMEARLRSDVIHAPL 146
EESP E+ SGD+IQFGV+V EN R K+THGCI++T+ L+ PDG EA+ P+
Sbjct: 1076 EESPMREVYSGDLIQFGVEVMENNRRGEKITHGCIIATLTLYHPDGREAK--------PV 921
Query: 147 PSPVDKVAANTPSMYSQELFQLSQYLQEALHREQMLEQKLATLQRLLAITQEASDTSWQA 206
P D T ++ SQ+L+QL+ +LQEALHRE+MLEQKL +LQ+L+ TQEA++ WQA
Sbjct: 920 PFLSDPNQPGT-TIQSQDLYQLAHFLQEALHREKMLEQKLGSLQQLVHXTQEAAEGGWQA 744
Query: 207 LIDEDRLLSRLEVMGNQLQACSKNQTEDSLRKELIALQEDKHNYETTAKESLRRVLQEKI 266
LIDED+LLSRLE++ NQL SKN +EDSLR+EL+ALQEDK NYETTAKESLRRVLQEK+
Sbjct: 743 LIDEDKLLSRLEMLENQLHIYSKNHSEDSLRQELVALQEDKINYETTAKESLRRVLQEKL 564
Query: 267 EVVRKLSEVERSLSNTEDECTHLKEMNERTQEELRELANKYNGAVNEIKDLSDKLK 322
+ V KLS++ERSL++ E EC HLKEM E +QEEL++LA +Y + E+ +L +KL+
Sbjct: 563 DAVTKLSDLERSLTSAEGECNHLKEMCESSQEELKQLATRYQDQLKEVMELQEKLQ 396
Score = 42.7 bits (99), Expect(2) = 4e-78, Method: Compositional matrix adjust.
Identities = 22/43 (51%), Positives = 31/43 (72%)
Frame = -3
Query: 342 LQHKIDEMEEKEQELQAKIEALQADNDFTNERLTALQEHLLSK 384
L K+++M ++E L AKIE+LQADNDF E+L A++ L SK
Sbjct: 339 LMEKLEDMIQQESSLSAKIESLQADNDFAREQLAAMKAKLESK 211
>14883
Length = 954
Score = 40.4 bits (93), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 19/38 (50%), Positives = 29/38 (76%)
Frame = -3
Query: 342 LQHKIDEMEEKEQELQAKIEALQADNDFTNERLTALQE 379
L K+++M ++E L AKIE+LQADNDF E+L A+++
Sbjct: 856 LMEKLEDMIQQESSLSAKIESLQADNDFAREQLAAMKD 743
>08467
Length = 1621
Score = 29.3 bits (64), Expect = 6.8, Method: Compositional matrix adjust.
Identities = 13/48 (27%), Positives = 25/48 (52%)
Frame = -3
Query: 219 VMGNQLQACSKNQTEDSLRKELIALQEDKHNYETTAKESLRRVLQEKI 266
V+ N + + +T + + L + KH+YE TA + LR +Q ++
Sbjct: 902 VINNLQEGIKRMRTRTHVHTHITLLFKPKHSYEATANQPLRYFVQSRL 759
>17475
Length = 884
Score = 28.9 bits (63), Expect = 9.5, Method: Compositional matrix adjust.
Identities = 21/56 (37%), Positives = 28/56 (50%), Gaps = 2/56 (3%)
Frame = -3
Query: 347 DEMEEKEQELQAKIEALQA--DNDFTNERLTALQEHLLSKSGGDCTFIHQFIECQK 400
+E+ + QELQAK+ AL DF N +AL+ L +G C F F C K
Sbjct: 174 EELMRQMQELQAKMAALGTK*SKDFRNS--SALR---LGNTGAYCRFFFYFHSCFK 22
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000295952 | hsapiens_gene_ensembl | sarcolemma
associated protein [Source:RefSeq_peptide;Acc:NP_009090]
(811 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
14682 268 4e-78
14883 40 0.003
08467 29 6.8
17475 29 9.5
>14682
Length = 1076
Score = 268 bits (685), Expect(2) = 4e-78, Method: Compositional matrix adjust.
Identities = 138/236 (58%), Positives = 181/236 (76%), Gaps = 3/236 (1%)
Frame = -1
Query: 90 EESPPCEILSGDIIQFGVDVTENTR---KVTHGCIVSTIKLFLPDGMEARLRSDVIHAPL 146
EESP E+ SGD+IQFGV+V EN R K+THGCI++T+ L+ PDG EA+ P+
Sbjct: 1076 EESPMREVYSGDLIQFGVEVMENNRRGEKITHGCIIATLTLYHPDGREAK--------PV 921
Query: 147 PSPVDKVAANTPSMYSQELFQLSQYLQEALHREQMLEQKLATLQRLLAITQEASDTSWQA 206
P D T ++ SQ+L+QL+ +LQEALHRE+MLEQKL +LQ+L+ TQEA++ WQA
Sbjct: 920 PFLSDPNQPGT-TIQSQDLYQLAHFLQEALHREKMLEQKLGSLQQLVHXTQEAAEGGWQA 744
Query: 207 LIDEDRLLSRLEVMGNQLQACSKNQTEDSLRKELIALQEDKHNYETTAKESLRRVLQEKI 266
LIDED+LLSRLE++ NQL SKN +EDSLR+EL+ALQEDK NYETTAKESLRRVLQEK+
Sbjct: 743 LIDEDKLLSRLEMLENQLHIYSKNHSEDSLRQELVALQEDKINYETTAKESLRRVLQEKL 564
Query: 267 EVVRKLSEVERSLSNTEDECTHLKEMNERTQEELRELANKYNGAVNEIKDLSDKLK 322
+ V KLS++ERSL++ E EC HLKEM E +QEEL++LA +Y + E+ +L +KL+
Sbjct: 563 DAVTKLSDLERSLTSAEGECNHLKEMCESSQEELKQLATRYQDQLKEVMELQEKLQ 396
Score = 42.7 bits (99), Expect(2) = 4e-78, Method: Compositional matrix adjust.
Identities = 22/43 (51%), Positives = 31/43 (72%)
Frame = -3
Query: 342 LQHKIDEMEEKEQELQAKIEALQADNDFTNERLTALQEHLLSK 384
L K+++M ++E L AKIE+LQADNDF E+L A++ L SK
Sbjct: 339 LMEKLEDMIQQESSLSAKIESLQADNDFAREQLAAMKAKLESK 211
>14883
Length = 954
Score = 40.4 bits (93), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 19/38 (50%), Positives = 29/38 (76%)
Frame = -3
Query: 342 LQHKIDEMEEKEQELQAKIEALQADNDFTNERLTALQE 379
L K+++M ++E L AKIE+LQADNDF E+L A+++
Sbjct: 856 LMEKLEDMIQQESSLSAKIESLQADNDFAREQLAAMKD 743
>08467
Length = 1621
Score = 29.3 bits (64), Expect = 6.8, Method: Compositional matrix adjust.
Identities = 13/48 (27%), Positives = 25/48 (52%)
Frame = -3
Query: 219 VMGNQLQACSKNQTEDSLRKELIALQEDKHNYETTAKESLRRVLQEKI 266
V+ N + + +T + + L + KH+YE TA + LR +Q ++
Sbjct: 902 VINNLQEGIKRMRTRTHVHTHITLLFKPKHSYEATANQPLRYFVQSRL 759
>17475
Length = 884
Score = 28.9 bits (63), Expect = 9.5, Method: Compositional matrix adjust.
Identities = 21/56 (37%), Positives = 28/56 (50%), Gaps = 2/56 (3%)
Frame = -3
Query: 347 DEMEEKEQELQAKIEALQA--DNDFTNERLTALQEHLLSKSGGDCTFIHQFIECQK 400
+E+ + QELQAK+ AL DF N +AL+ L +G C F F C K
Sbjct: 174 EELMRQMQELQAKMAALGTK*SKDFRNS--SALR---LGNTGAYCRFFFYFHSCFK 22
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000261535 | hsapiens_gene_ensembl | Rho-associated
protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled-
coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (Renal
carcinoma antigen NY-REN-35). [Source:Uniprot/SWISSPROT;Acc:Q13464]
(1354 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
03240 289 5e-78
30755 143 6e-34
18484 111 2e-25
27405 114 4e-25
29793 109 7e-24
31885 103 4e-22
12721 102 1e-21
00300 98 2e-20
18921 93 8e-19
14420 93 8e-19
26560 91 4e-18
09606 88 2e-17
13592 88 3e-17
00486 87 3e-17
01707 87 4e-17
15910 84 4e-16
01392 80 6e-15
26156 66 8e-15
17932 78 3e-14
05015 58 4e-14
12786 76 1e-13
13212 74 3e-13
17975 74 4e-13
01718 73 6e-13
01756 72 2e-12
13066 72 2e-12
06405 70 5e-12
01060 70 5e-12
18663 70 7e-12
19094 69 2e-11
26711 67 6e-11
21079 66 8e-11
16708 65 2e-10
14126 62 2e-09
21433 60 4e-09
04591 60 5e-09
25019 59 1e-08
03508 56 8e-08
17722 56 1e-07
11185 55 1e-07
29581 55 1e-07
19761 55 2e-07
27546 53 9e-07
00392 51 4e-06
28157 50 5e-06
00715 49 2e-05
04138 49 2e-05
01966 48 2e-05
19301 47 4e-05
37063 47 4e-05
14116 47 4e-05
37602 46 9e-05
21808 45 2e-04
07940 44 3e-04
07833 44 4e-04
32359 34 5e-04
06358 44 6e-04
32957 43 8e-04
00638 43 8e-04
14748 43 0.001
12672 42 0.001
04852 42 0.001
29590 42 0.002
11780 42 0.002
18996 40 0.005
02638 40 0.005
17300 40 0.007
07291 40 0.009
11404 39 0.013
13840 39 0.015
33586 39 0.015
18401 39 0.017
29360 39 0.021
20152 37 0.041
25829 37 0.048
18481 37 0.049
26009 36 0.081
31489 36 0.086
01106 36 0.11
17516 33 0.71
28040 33 0.99
27274 33 1.1
20640 32 1.3
32357 31 3.8
17623 31 3.9
21210 30 8.1
30339 30 8.4
11353 30 9.3
>03240
Length = 1683
Score = 289 bits (740), Expect = 5e-78, Method: Compositional matrix adjust.
Identities = 154/358 (43%), Positives = 211/358 (58%), Gaps = 46/358 (12%)
Frame = -3
Query: 64 NKIRDLRMKAED--YEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAFF 121
N IR R K + +E +K +G GAFGEV L R T +YAMK L K +++KR+ A
Sbjct: 1327 NYIRLKRAKMDKCMFEKIKTLGVGAFGEVSLCRKNDTGMLYAMKTLRKSDVLKRNQVAHV 1148
Query: 122 WEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDV-PEKWARFYTA 180
ERDI+A A++ WVV+L+Y+FQD YLY VM+Y+PGGDL+ L+ ++ E ARFY A
Sbjct: 1147 KAERDILAEADNEWVVKLYYSFQDHNYLYFVMDYVPGGDLMGLLIRMEILDEPLARFYVA 968
Query: 181 EVVLALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTCMKM---------NKEGM--- 228
E+V A++++H MGFIHRD+KPDN+L+D++GH+KL DFG C ++G
Sbjct: 967 ELVQAIESVHRMGFIHRDIKPDNILIDRNGHIKLTDFGLCTGFRWTHNSKYYQRDGTHAR 788
Query: 229 -----VRCD--------------------------TAVGTPDYISPEVLKSQGGDGYYGR 257
V+C + VGTP+YI+PEVL GG Y
Sbjct: 787 QDSMEVKCQLDEQCQCEILKPLERRRKREQRCLAHSLVGTPNYIAPEVLSRLGG---YTS 617
Query: 258 ECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLTFPDDNDISKEAKNLICAFL 317
CDWWSVGV L+EMLVG PFYA++ T K++N K+ L P ++++S+ AK+LI
Sbjct: 616 VCDWWSVGVILFEMLVGHPPFYANTPAETQYKVINWKDMLKIPRESNLSQPAKDLILRLC 437
Query: 318 TDREVRLGRNGVEEIKRHLFFKNDQWAWETLRDTVAPVVPDLSSDIDTSNFDDLEEDK 375
+ RLG NG EIK H+FF +ETLR P VP++ DTSNFD ++ DK
Sbjct: 436 CGSDDRLGLNGAGEIKTHMFFAGVN--FETLRKQQPPYVPNIRYATDTSNFDPVDPDK 269
>30755
Length = 1137
Score = 143 bits (360), Expect = 6e-34, Method: Composition-based stats.
Identities = 90/218 (41%), Positives = 122/218 (55%), Gaps = 5/218 (2%)
Frame = +2
Query: 172 EKWARFYTAEVVLALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRC 231
E+ RFY AE++ AL +HS G I+RD+K +N+LLDK GH+K+ADFG C + G
Sbjct: 29 EERTRFYGAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCKEDITYGRT-T 205
Query: 232 DTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIM 291
T GTP+Y++PEVL D YGR DWW GV +YEM+ G PFY ++ I+
Sbjct: 206 KTFCGTPEYLAPEVLD----DNDYGRAVDWWGTGVVMYEMICGRLPFYNRDHDVLFTLIL 373
Query: 292 NHKNSLTFPDDNDISKEAKNLICAFLT-DREVRL--GRNGVEEIKRHLFFKNDQWAWETL 348
+ FP +I+ EAK+L+ L D RL G++ V+EI+ H FF + W
Sbjct: 374 --VEDVKFP--RNITDEAKSLLSGLLAKDPRNRLGGGQDDVKEIQAHPFFASINWTDLVQ 541
Query: 349 RDTVAPVVPDLSSDIDTSNFDDLEEDKGE--EETFPIP 384
+ P P ++SD DT FD EE GE E T P P
Sbjct: 542 KKITPPFKPQVTSDTDTRYFD--EEFTGESVELTPPDP 649
>18484
Length = 635
Score = 111 bits (278), Expect(2) = 2e-25, Method: Composition-based stats.
Identities = 64/158 (40%), Positives = 89/158 (56%), Gaps = 4/158 (2%)
Frame = +1
Query: 172 EKWARFYTAEVVLALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMV-- 229
E A FY AE+ + L +H G I+RD+K DN++LD GH+K+ADFG C KEGM
Sbjct: 40 EPVAAFYAAEIAVGLFFLHDQGIIYRDLKLDNVMLDSEGHIKIADFGMC----KEGMTGD 207
Query: 230 -RCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYS 288
T GTPDYI+PE++ Q Y + DWW+ GV L+EML G PF + +S
Sbjct: 208 ATTRTFCGTPDYIAPEIVLYQP----YSKSVDWWAYGVLLFEMLAGQPPFDGEDEDELFS 375
Query: 289 KIMNHKNSLTFPDDNDISKEAKNLICAFLTDREV-RLG 325
I +H ++++P +S+EA +L L RLG
Sbjct: 376 SITDH--NVSYP--KAMSREAVSLCKGLLMKNPTKRLG 477
Score = 23.5 bits (49), Expect(2) = 2e-25, Method: Composition-based stats.
Identities = 12/44 (27%), Positives = 19/44 (43%)
Frame = +2
Query: 326 RNGVEEIKRHLFFKNDQWAWETLRDTVAPVVPDLSSDIDTSNFD 369
+NG +I+ H FF+ W + P P ++ NFD
Sbjct: 485 QNGERDIRDHAFFRRIVWDKIKSMEVQPPYKPKITDRRKAENFD 616
>27405
Length = 532
Score = 114 bits (284), Expect = 4e-25, Method: Composition-based stats.
Identities = 68/183 (37%), Positives = 103/183 (56%), Gaps = 6/183 (3%)
Frame = -3
Query: 86 AFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFAN----SPWVVQLFY 141
FGEV R T K+YAMK L K + + ER +++ + SP++V + Y
Sbjct: 530 GFGEVYGCRKADTGKMYAMKCLDKKRIKMKGGETLALNERIMLSLVSTGEGSPFIVCMTY 351
Query: 142 AFQDDRYLYMVMEYMPGGDLVNLMSNYDV-PEKWARFYTAEVVLALDAIHSMGFIHRDVK 200
AFQ L +++ M GGDL +S + V EK RFY AEV+L L+ +HS ++RD+K
Sbjct: 350 AFQTPEKLCFILDLMNGGDLHYHLSQHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLK 171
Query: 201 PDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPDYISPEVL-KSQGGDGYYGREC 259
P N+LLD++GH++++D G +K+ + +VGT Y++PEVL K Q Y
Sbjct: 170 PANILLDENGHVRISDLGLACDFSKK---KPHASVGTHGYMAPEVLMKGQA----YDSSA 12
Query: 260 DWW 262
DW+
Sbjct: 11 DWF 3
>29793
Length = 1088
Score = 109 bits (273), Expect = 7e-24, Method: Compositional matrix adjust.
Identities = 95/295 (32%), Positives = 154/295 (52%), Gaps = 12/295 (4%)
Frame = +2
Query: 733 RVVQIEKQCSMLDVDLKQSQQKLEHLTGNKERMEDEVKNLTLQLEQESNK-RLLLQNELK 791
R+++ EK+ S + VDL Q QQ++E + + ++ + ++ L+Q ++K
Sbjct: 176 RLLETEKKBSEMGVDLMQLQQRVERCSPSYKQRSTRAGGCPCKWSRKCKTYDNLMQGDIK 355
Query: 792 TQAFEADNLKGLEKQMKQEINTLLEAKRLLEFELAQLTKQYRGNEGQMRELQDQLEAEQY 851
T + + + K EKQ+ +EI+ L K+ + E+ +L + +E QMRE Q+QLEAE Y
Sbjct: 356 TTSMDLNKAKSKEKQLAKEISDLKHEKKTADQEIRRLKDEISVSELQMRETQEQLEAENY 535
Query: 852 FSTLYKTQVXXXXXXXXXXXXXXXXXXQELQN---EKETLATQLDLAETKAESEQLARGL 908
FS+LYKTQV ++QN EKE++ TQ+ L TKA+SE LARG+
Sbjct: 536 FSSLYKTQVKELKEEVDEKQKQIQDLTSDVQNILHEKESILTQVQLLHTKADSEALARGI 715
Query: 909 LEEQYFELTQES-------KKAASRNRQEITDKDHTVSRLEEANSMLTKDIEILRRENEE 961
EEQ ++ +E K+ SR++ E+ K+ ++ LE+ + + E L+++ ++
Sbjct: 716 AEEQLSDVEKEKTMLELEIKELMSRHKNEMNKKESQLAALEDQKRDYSINTEKLQQDKDD 895
Query: 962 LTXXXXX-XXXXXXXXXXXXISNLKAAFEKNINTERTLKTQAVNKLAEIMNRKDF 1015
L LK K + E+ K QAVNKLAEIMNRK+F
Sbjct: 896 LNNKIKRLAEDLQSSKNMSEFDKLK----KQLEDEKLKKIQAVNKLAEIMNRKEF 1048
>31885
Length = 529
Score = 103 bits (257), Expect = 4e-22, Method: Compositional matrix adjust.
Identities = 58/162 (35%), Positives = 91/162 (56%), Gaps = 5/162 (3%)
Frame = -2
Query: 126 DIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDL-VNLMSNYDVPEKWARFYTAEVVL 184
D++ + P++V L+YAFQD+ L+MV++ GGDL ++ E +FY ++ L
Sbjct: 516 DMLTRLDHPFLVNLWYAFQDEEDLFMVVDLFLGGDLRYHMQQEVSFREDCVKFYLCQLAL 337
Query: 185 ALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPDYISPE 244
LD + S +HRD+KPDN+LLD+ GH + DF ++ + + + GT Y++PE
Sbjct: 336 VLDYLRSQKIVHRDIKPDNILLDEQGHCHVTDFNIATQLEDDELAT--STSGTRPYMAPE 163
Query: 245 V----LKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADS 282
V + + G YG DWWS+GV L+E+L PF S
Sbjct: 162 VYGVAINERRG---YGFPVDWWSLGVSLFELLKKRRPFSVHS 46
>12721
Length = 821
Score = 102 bits (253), Expect = 1e-21, Method: Composition-based stats.
Identities = 60/198 (30%), Positives = 109/198 (55%)
Frame = +1
Query: 82 IGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFY 141
IG G+ G V + + R++ + K ++ K+ + E +M + P +V+++
Sbjct: 112 IGEGSTGIVCIATSRDGRQM----AVKKMDLRKQQRRELLFNEVVVMRDYHHPNIVEMYN 279
Query: 142 AFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKWARFYTAEVVLALDAIHSMGFIHRDVKP 201
++ + L++VME+M GG L ++++N + E + AL +H+ G IHRD+K
Sbjct: 280 SYLVNDELWVVMEFMEGGALTDIVTNNRMDEVQIATVCRACLKALAFLHANGVIHRDIKS 459
Query: 202 DNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPDYISPEVLKSQGGDGYYGRECDW 261
D++LL G +KL DFG C ++ ++ R + VGTP +++PEV+ YG E D
Sbjct: 460 DSILLSHDGKVKLXDFGFCAQVTQDLQKR-KSLVGTPYWMAPEVISRLP----YGPEVDI 624
Query: 262 WSVGVFLYEMLVGDTPFY 279
WS+G+ + EM+ + PF+
Sbjct: 625 WSLGIMVMEMIDAEPPFF 678
>00300
Length = 2318
Score = 98.2 bits (243), Expect = 2e-20, Method: Compositional matrix adjust.
Identities = 64/200 (32%), Positives = 99/200 (49%), Gaps = 2/200 (1%)
Frame = -1
Query: 82 IGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFY 141
IG G FG+V + ST ++ A+K + KF+ +E I +V+ +
Sbjct: 1634 IGEGQFGKVYTAVNMSTGELMALKEM-KFQPNDLQQLREMCDEIKIFEGIQHENLVKYYG 1458
Query: 142 AFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKWARFYTAEVVLALDAIHSMGFIHRDVKP 201
+ M MEY G + + +PE R YT E+VLA++ +H +HRD+K
Sbjct: 1457 VEVHKDEMLMFMEYCDTGT-IEEAAKMGLPEYLIRRYTREIVLAVNHLHENSIVHRDIKG 1281
Query: 202 DNMLLDKSGHLKLADFGTCMKMNKEGMVRCD--TAVGTPDYISPEVLKSQGGDGYYGREC 259
N+ L +GH+KL DFG +K+ + + VGT Y++PEV +Q G YGR
Sbjct: 1280 ANIFLTSNGHVKLGDFGCSVKLKSHTTMPGEFHNLVGTTAYMAPEVF-TQNDQGGYGRAA 1104
Query: 260 DWWSVGVFLYEMLVGDTPFY 279
D WS+G + EM G P++
Sbjct: 1103 DIWSLGCVVIEMATGKRPWH 1044
>18921
Length = 697
Score = 92.8 bits (229), Expect = 8e-19, Method: Compositional matrix adjust.
Identities = 63/211 (29%), Positives = 111/211 (52%), Gaps = 2/211 (0%)
Frame = +2
Query: 76 YEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSPW 135
++++ +G G++G V HK T +V A+K ++ +D +E IM +S +
Sbjct: 35 FDILGKLGEGSYGSVFKSLHKETGQVLAIK-----QVPVDTDLQEIIKEISIMQQCDSKY 199
Query: 136 VVQLFYAFQDDRYLYMVMEYMPGGDLVNLMS--NYDVPEKWARFYTAEVVLALDAIHSMG 193
+V+ + ++ + L++VMEY G + ++M N + E+ + L +HS
Sbjct: 200 IVKYYGSYFKNTDLWIVMEYCGAGSVSDIMRLRNKTLVEREIATILYYTLKGLXYLHSRR 379
Query: 194 FIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPDYISPEVLKSQGGDG 253
IHRD+K N+LL+ GH KLADFG ++ + M + +T +GTP +++PEV++ G
Sbjct: 380 KIHRDIKAGNILLNNEGHAKLADFGVAGQLT-DTMAKRNTVIGTPYWMAPEVIQEIG--- 547
Query: 254 YYGRECDWWSVGVFLYEMLVGDTPFYADSLV 284
Y D WS+G+ EM G P S++
Sbjct: 548 -YDCVADIWSLGITALEMAEGKPPVMETSIL 637
>14420
Length = 528
Score = 92.8 bits (229), Expect = 8e-19, Method: Compositional matrix adjust.
Identities = 51/146 (34%), Positives = 82/146 (56%)
Frame = +2
Query: 133 SPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKWARFYTAEVVLALDAIHSM 192
+P +V ++ L++VME++ GG L ++++ + E E + AL+ +H
Sbjct: 77 NPNIVNYLDSYLVGEELWVVMEFLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHEN 256
Query: 193 GFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPDYISPEVLKSQGGD 252
IHRD+K DN+LL G +KL DFG C +++ E R T VGTP +++PEV+ +
Sbjct: 257 QVIHRDIKSDNILLGMDGSVKLTDFGFCAQLSPEQSKR-STMVGTPYWMAPEVVTRK--- 424
Query: 253 GYYGRECDWWSVGVFLYEMLVGDTPF 278
YG D WS+GV EM+ G+ P+
Sbjct: 425 -QYGPTVDIWSLGVMCIEMIEGEPPY 499
>26560
Length = 398
Score = 90.5 bits (223), Expect = 4e-18, Method: Composition-based stats.
Identities = 47/108 (43%), Positives = 69/108 (63%), Gaps = 1/108 (0%)
Frame = -1
Query: 172 EKWARFYTAEVVLALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRC 231
EK RFY AEV+L L+ +HS ++RD+KP N+LLD++GH++++D G +K+ R
Sbjct: 359 EKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGLACDFSKK---RP 189
Query: 232 DTAVGTPDYISPEVL-KSQGGDGYYGRECDWWSVGVFLYEMLVGDTPF 278
+VGT Y++PEVL K Q Y DW+S G LY++L G +PF
Sbjct: 188 HASVGTHGYMAPEVLMKGQS----YDSSADWFSFGCMLYKLLKGHSPF 57
>09606
Length = 1300
Score = 88.2 bits (217), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 66/246 (26%), Positives = 115/246 (46%), Gaps = 22/246 (8%)
Frame = -3
Query: 69 LRMKAEDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAFFWEERDIM 128
L + E++ + + +G+G + R K T A+ + K + + +++ DI
Sbjct: 1130 LITRMENFVLYEELGKGEHSIIYKGRRKGTINFVAIHCIEKCKRPEVTNTVRM--THDI- 960
Query: 129 AFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMS-NYDVPEKWARFYTAEVVLALD 187
+ P VVQ ++ +L++V+E GG L ++++ ++ +PE R + +V L
Sbjct: 959 ---SHPNVVQFHEWYETSNHLWLVVELCTGGSLADILAQDHHLPETSIRDFGIHLVTGLH 789
Query: 188 AIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTC-----------MKMNKEG--------- 227
IHS+G + D++P +LLD SG LK ADFG K + G
Sbjct: 788 YIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQWNIQSAE 609
Query: 228 -MVRCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGT 286
M++ G+P Y++PEV QG + D W++G YEM G PF ++ T
Sbjct: 608 EMMKQVPTSGSPTYMAPEVF--QGAEP--SIMSDLWALGCVFYEMFSGHPPFLGETYDIT 441
Query: 287 YSKIMN 292
K++N
Sbjct: 440 KDKVLN 423
>13592
Length = 980
Score = 87.8 bits (216), Expect = 3e-17, Method: Compositional matrix adjust.
Identities = 66/205 (32%), Positives = 106/205 (51%), Gaps = 8/205 (3%)
Frame = +2
Query: 82 IGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAFF---WEERDIMAFANSPWVVQ 138
IG+G FG+V + +T ++ AMK ++ I+ ++ EE I+ +V+
Sbjct: 8 IGQGRFGKVYTAVNNNTGELMAMKEIA----IQPGETRALKNVAEELKILEGIKHKNLVR 175
Query: 139 LFYAFQDDRY-LYMVMEYMPGGDLVNLMS-NYDVPEKWARFYTAEVVLALDAIHSMGFIH 196
+Y + R L + ME G L +L+ +PE +R +TA+++ + +H G +H
Sbjct: 176 -YYGIEVHREELLIFMELCSEGTLESLVELTGGLPEALSRRFTAQLLSGVAELHKHGIVH 352
Query: 197 RDVKPDNM-LLDKSGHLKLADFGTCMKMNKEGMVRCD--TAVGTPDYISPEVLKSQGGDG 253
RD+K N+ L+D S LKL DFG+ +K+ V + VGT Y++PEV DG
Sbjct: 353 RDIKTANIFLVDGSNSLKLGDFGSAVKIQAHTTVPGELQGYVGTQAYMAPEVFTKTNSDG 532
Query: 254 YYGRECDWWSVGVFLYEMLVGDTPF 278
+GR D WSVG + EM G P+
Sbjct: 533 -HGRLADIWSVGCVVVEMASGKRPW 604
>00486
Length = 797
Score = 87.4 bits (215), Expect = 3e-17, Method: Composition-based stats.
Identities = 54/140 (38%), Positives = 74/140 (52%), Gaps = 3/140 (2%)
Frame = -2
Query: 233 TAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMN 292
T GT +Y++PE+L G +G+ DWWS+G +Y+ML G PF A++ T KI+
Sbjct: 781 TFCGTIEYMAPEILTRTG----HGKAVDWWSLGALMYDMLTGSPPFTAENRKKTIDKIL- 617
Query: 293 HKNSLTFPDDNDISKEAKNLICAFLTDREV-RL--GRNGVEEIKRHLFFKNDQWAWETLR 349
K L P ++ EA+ LI L RL G + IK H FF+N WA LR
Sbjct: 616 -KGKLNLPP--YLTNEARGLIKKLLRKNPAERLGGGHDDSGPIKDHQFFRNTNWALLALR 446
Query: 350 DTVAPVVPDLSSDIDTSNFD 369
P P+++SD DTS FD
Sbjct: 445 RAEPPFRPNVTSDEDTSQFD 386
>01707
Length = 757
Score = 87.0 bits (214), Expect = 4e-17, Method: Compositional matrix adjust.
Identities = 65/208 (31%), Positives = 105/208 (50%), Gaps = 5/208 (2%)
Frame = +1
Query: 72 KAEDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFE---MIKRSDSAFFWEERDIM 128
+ E YE + IG G++G V R+K T ++ A+K + E +IK+ E ++
Sbjct: 58 RMEKYEKIGKIGEGSYGVVFKCRNKETSQLVAIKKFVESEDDPLIKKIAM----REIRML 225
Query: 129 AFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNY--DVPEKWARFYTAEVVLAL 186
P +V+L F+ + L++V +Y+ L+N + Y +PE + + +LA+
Sbjct: 226 KQLKHPNLVRLIEVFRRKKRLHLVFDYV-DHTLLNELDRYPRGLPEPMVKRIIYQTLLAV 402
Query: 187 DAIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPDYISPEVL 246
+ H IHRDVKP+N+L+ + G +KL DFG + G D V T Y +PE+L
Sbjct: 403 NFCHQYNTIHRDVKPENILITRQGQVKLCDFGFARILTGPGDEYTD-YVATRWYRAPELL 579
Query: 247 KSQGGDGYYGRECDWWSVGVFLYEMLVG 274
GD YG D W++G E+L G
Sbjct: 580 V---GDTQYGPPVDVWAIGCVFAELLTG 654
>15910
Length = 1361
Score = 84.0 bits (206), Expect = 4e-16, Method: Compositional matrix adjust.
Identities = 53/139 (38%), Positives = 80/139 (57%), Gaps = 5/139 (3%)
Frame = +2
Query: 180 AEVVLALDAIHSMGFIHRDVKPDNML---LDKSGHLKLADFGTCMKMNKEGMVRCDTAVG 236
++++ + IH+ G +HRD+KP+N+L + LKLADFG + E V+ T G
Sbjct: 485 SDILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLADFGLSRIIEPE--VQMSTVCG 658
Query: 237 TPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNS 296
TP Y +PEVLK GD Y D WSVGV Y +L G PF+A++ Y KI+ K
Sbjct: 659 TPGYCAPEVLK---GDKY-TPSVDMWSVGVIAYILLCGYEPFFAENEFEMYRKII--KGE 820
Query: 297 LTFPDD--NDISKEAKNLI 313
F ++ ++IS+ AK+++
Sbjct: 821 YKFDEEYWSEISENAKDVV 877
>01392
Length = 1806
Score = 80.1 bits (196), Expect = 6e-15, Method: Composition-based stats.
Identities = 44/117 (37%), Positives = 65/117 (55%), Gaps = 8/117 (6%)
Frame = -1
Query: 172 EKWARFYTAEVVLALDAIHSMGFIHRDVKPDNML---LDKSGHLKLADFGTCMKMNKEG- 227
E+ A + ALD +HS G HRD+KP+N+L LD +K+ DF ++ +G
Sbjct: 1794 EREASLVVRHIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGISCDGD 1615
Query: 228 ---MVRCDTAVGTPDYISPEVLKSQGGDGY-YGRECDWWSVGVFLYEMLVGDTPFYA 280
T VG+ +Y++PEV+ + GD + Y + CD WS+G+ LY ML G PFY
Sbjct: 1614 GTKTPELLTPVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILYIMLCGYPPFYG 1444
>26156
Length = 479
Score = 66.2 bits (160), Expect(2) = 8e-15, Method: Compositional matrix adjust.
Identities = 38/112 (33%), Positives = 68/112 (60%), Gaps = 4/112 (3%)
Frame = -1
Query: 70 RMKAEDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAFFWEERDIMA 129
++ D+ +++VIGRG++ +V V HK T+++YAMK++ K E++ D W + +
Sbjct: 401 KLGLTDFLLLRVIGRGSYAKVLQVEHKRTKRIYAMKVIKK-ELVN-DDEDIDWVQTEKHV 228
Query: 130 F---ANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLV-NLMSNYDVPEKWARF 177
F N P++V L FQ + L+ V+E++ GGDL+ ++ +PE+ ARF
Sbjct: 227 FETATNYPFLVGLHSCFQSESRLFFVIEFVNGGDLMFHMQRQRRLPEEHARF 72
Score = 33.5 bits (75), Expect(2) = 8e-15, Method: Composition-based stats.
Identities = 12/24 (50%), Positives = 19/24 (79%)
Frame = -3
Query: 177 FYTAEVVLALDAIHSMGFIHRDVK 200
FY+AE+ LAL+ +H G ++RD+K
Sbjct: 75 FYSAEICLALNFLHKRGIVYRDLK 4
>17932
Length = 597
Score = 77.8 bits (190), Expect = 3e-14, Method: Composition-based stats.
Identities = 44/110 (40%), Positives = 67/110 (60%), Gaps = 4/110 (3%)
Frame = -3
Query: 300 PDDNDISKEAKNLICAFLTDREVRLGRNGVEEIKRHLFFKNDQWAWETLRDTVAPVVPDL 359
P + +SKEA++LI L+D + RLG E+++H FFK WA +R+ + P VP +
Sbjct: 475 PPHSSVSKEARDLISQLLSDGKSRLGW---PELQQHPFFKTVDWA--NIRNAMPPYVPSI 311
Query: 360 SSDIDTSNFDDLEEDKGEE--ETF--PIPKAFVGNQLPFVGFTYYSNRRY 405
SS DTS+FD++E+ + ++F P + F G LPFVGFTY+ R+
Sbjct: 310 SSLDDTSHFDEVEKARPAPNIDSFHQPSSRDFTGRHLPFVGFTYFHPPRH 161
Score = 52.0 bits (123), Expect = 2e-06, Method: Composition-based stats.
Identities = 24/51 (47%), Positives = 32/51 (62%), Gaps = 2/51 (3%)
Frame = -2
Query: 261 WWSVGVFLYEMLVGDTPFYAD--SLVGTYSKIMNHKNSLTFPDDNDISKEA 309
WWS+GV YEML G TPF D S+V TY+ IMN+K + + P + + A
Sbjct: 596 WWSLGVCAYEMLFGCTPFTDDDGSMVATYNNIMNYKTNSSSPSQQRVQRGA 444
>05015
Length = 894
Score = 58.2 bits (139), Expect(2) = 4e-14, Method: Compositional matrix adjust.
Identities = 38/88 (43%), Positives = 54/88 (61%), Gaps = 1/88 (1%)
Frame = +3
Query: 1038 QLELNQEREKFNQMVVKHQKELNDMQAQLVEECAHRNELQMQLASKESDIEQLRAKL-LD 1096
Q EL EREK+N+MV K Q+++ + Q + EE R LQM++ +K+S+IEQLR KL L
Sbjct: 621 QQELTMEREKYNKMVEKMQRDVAEAQQNVYEESLSRQRLQMEMDAKDSEIEQLRLKLSLF 800
Query: 1097 LSDSTSVASFPSADETDGNLPESRIEGW 1124
+D TS S S +E+ + E GW
Sbjct: 801 NADVTSTHSTGSLEES---VVEESTSGW 875
Score = 39.3 bits (90), Expect(2) = 4e-14, Method: Compositional matrix adjust.
Identities = 23/45 (51%), Positives = 31/45 (68%), Gaps = 2/45 (4%)
Frame = +2
Query: 1000 TQAVNKLAEIMNRKDFK--IDRKKANTQDLRKKEKENRKLQLELN 1042
+QAVNKLAEIMNRK+F+ + KA DL++KEK+ R+ N
Sbjct: 500 SQAVNKLAEIMNRKEFRRGGGKDKAVGSDLKRKEKDLRRGSTRTN 634
>12786
Length = 460
Score = 75.9 bits (185), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 46/121 (38%), Positives = 68/121 (56%), Gaps = 18/121 (14%)
Frame = -3
Query: 176 RFYTAEVVLALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTC--MKMNKEGMVRCDT 233
+FY E++ A+ A+H+ G IH D+KP N +L +G+LKL DFG ++ +K +++ D+
Sbjct: 401 KFYWREMLRAVKALHNEGVIHSDLKPANFML-VAGNLKLIDFGIANTLQQDKTSVLK-DS 228
Query: 234 AVGTPDYISPEVLK---------SQGGDGY-------YGRECDWWSVGVFLYEMLVGDTP 277
VGTP Y+SPE + S DG+ G D WS+G LY M+ G TP
Sbjct: 227 RVGTPSYMSPEAIMAACDDSADDSMEEDGHRTKPKYKVGVRSDVWSLGCILYNMVYGRTP 48
Query: 278 F 278
F
Sbjct: 47 F 45
>13212
Length = 1067
Score = 74.3 bits (181), Expect = 3e-13, Method: Compositional matrix adjust.
Identities = 44/116 (37%), Positives = 66/116 (56%), Gaps = 3/116 (2%)
Frame = -1
Query: 159 GDLVNLMSNYDVPEKWAR--FYTAEVVLALDAIHSMGFIHRDVKPDNMLLDKSGHLKLAD 216
G L ++M + + P A+ + E+ +ALD +H IHRD+K N+LL G +KLAD
Sbjct: 1028 GALDSIMVDLEKPMTEAQICYVCHEMCMALDFLHRHHVIHRDIKAGNVLLTIDGEVKLAD 849
Query: 217 FGTCMKMNKEGMVRCDTAVGTPDYISPEVLKSQG-GDGYYGRECDWWSVGVFLYEM 271
FG K N + + DT +GTP +++PEV+ + D Y + D WS+GV L E
Sbjct: 848 FGVSAK-NTQTQQKRDTFIGTPYWMAPEVVLCETLKDTPYDFKADIWSLGVTLIEF 684
>17975
Length = 449
Score = 73.9 bits (180), Expect = 4e-13, Method: Composition-based stats.
Identities = 48/144 (33%), Positives = 79/144 (54%), Gaps = 5/144 (3%)
Frame = +3
Query: 87 FGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFYAFQDD 146
F V+L RH T + A+K++ K ++ + S S F E R M P VV+L+
Sbjct: 6 FAVVKLARHVFTGEKVAVKVIDKTKLDEVSRSHLFQEVR-CMKLVQHPNVVRLYEVIDTQ 182
Query: 147 RYLYMVMEYMPGGDLVNLMSNYD--VPEKWARFYTAEVVLALDAIHSMGFIHRDVKPDNM 204
LY+++E GGD+ + + + + EK A+ Y ++V A+ H + +HRD+KP+N+
Sbjct: 183 TKLYLILELGDGGDMYDYIMRHSGGLEEKLAKRYFRQIVEAISYCHKLHVVHRDLKPENV 362
Query: 205 L-LDKSGHLKLADFG--TCMKMNK 225
+ +K G +KL DFG TC+ K
Sbjct: 363 VFFEKPGLVKLTDFGFSTCLLQAK 434
>01718
Length = 959
Score = 73.2 bits (178), Expect = 6e-13, Method: Compositional matrix adjust.
Identities = 59/200 (29%), Positives = 95/200 (47%), Gaps = 10/200 (5%)
Frame = +3
Query: 82 IGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFY 141
IG G F EV V H+ T +V A+K+ + S+ E ++ +++
Sbjct: 171 IGAGFFSEVFKVTHRITGQVMALKMNTM-----TSNRHNMLREVQLLNRLQHANILRFMG 335
Query: 142 AFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKWARFYTAEVVLA--LDAIHSMGFIHRDV 199
+ L+ + EY+P G+L L+ D W + + LA LD +HS FIHRD+
Sbjct: 336 VCVHEGQLHALTEYIPSGNLEQLLEKKDEELPWTQRIQLTLGLARGLDYLHSTRFIHRDL 515
Query: 200 KPDNMLL---DKSG-HLKLADFGTCMK----MNKEGMVRCDTAVGTPDYISPEVLKSQGG 251
N+L+ D G H +ADFG K ++KE + VG+P +++PEVL
Sbjct: 516 TSKNILIRREDNHGYHAVIADFGLATKIPDPLDKEKL----PTVGSPYWMAPEVLNGH-- 677
Query: 252 DGYYGRECDWWSVGVFLYEM 271
+Y D +SVG+ + E+
Sbjct: 678 --FYNERADLFSVGIIMCEI 731
>01756
Length = 1858
Score = 71.6 bits (174), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 72/211 (34%), Positives = 97/211 (45%), Gaps = 15/211 (7%)
Frame = -3
Query: 76 YEVVKVIGRGAFGEVQLVRHKSTRKVYAMK-LLSKFEMIKRSDSAFFWEERDIMAFANSP 134
YE + IG+G FGEV R K T++V AMK +L E +A E I+ N
Sbjct: 1736 YEKLAKIGQGTFGEVFKARCKKTKQVVAMKKVLMDNEKEGFPITAL--REIKILQLLNHE 1563
Query: 135 WVVQLF-----YAFQDDRY---LYMVMEYMPGGDLVNLMSN----YDVPEKWARFYTAEV 182
VV L A +RY Y+V E+ DL L+SN +++PE + ++
Sbjct: 1562 NVVDLIEICSTKATSANRYKSMFYLVFEFCEH-DLAGLLSNMSVVFNLPE--IKEVMKQL 1392
Query: 183 VLALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFGT--CMKMNKEGMVRCDTAVGTPDY 240
+ L IH +HRD+K N+L+ K G LKLADFG +N R V T Y
Sbjct: 1391 MNGLYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWY 1212
Query: 241 ISPEVLKSQGGDGYYGRECDWWSVGVFLYEM 271
PE+L GD Y D W G + EM
Sbjct: 1211 RPPELLL---GDRNYSTAIDQWGAGCIMAEM 1128
>13066
Length = 551
Score = 71.6 bits (174), Expect = 2e-12, Method: Composition-based stats.
Identities = 47/151 (31%), Positives = 78/151 (51%), Gaps = 5/151 (3%)
Frame = +3
Query: 120 FFWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYD-VPEKWARFY 178
FF E D++ + P+++Q+ Q ++ M + GDL+ + V EK A+ +
Sbjct: 114 FFPRELDLLTKLDHPYIIQIHSILQRXPKNFIFMRFAERGDLLTYIQEVGFVKEKQAKIW 293
Query: 179 TAEVVLALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFG-TCMKMNKEG---MVRCDTA 234
++ AL+ +HS HRD+K +N+LL ++KLADFG C + + G M R T
Sbjct: 294 FYQMTTALNYLHSYDVAHRDLKCENILLSSHFNVKLADFGFACACITESGEKYMSR--TY 467
Query: 235 VGTPDYISPEVLKSQGGDGYYGRECDWWSVG 265
G+ Y +PE++ G Y + D WS+G
Sbjct: 468 CGSAAYAAPEIVY---GAPYAPKVADAWSLG 551
>06405
Length = 1965
Score = 70.1 bits (170), Expect = 5e-12, Method: Compositional matrix adjust.
Identities = 71/259 (27%), Positives = 112/259 (43%), Gaps = 6/259 (2%)
Frame = +1
Query: 35 DALVYDLDFPALRKNKNIDNFLSRYKDTINKIRDLRMKAEDYEVV--KVIGRGAFGEVQL 92
D LV L +PA ++ K +S D R + E E+ +G G +G+V
Sbjct: 160 DGLVTTLLYPAPKRQKPTVFGVSPEPD--------RWEIERTEIAMKHRLGGGQYGDVYE 315
Query: 93 VRHKSTRKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFYAFQDDRYLYMV 152
K K+ A+K L K + + +D F EE IM P +VQL + Y+V
Sbjct: 316 AMWKRYNKIVAVKTL-KEDTMALND---FLEEAAIMKEMKHPNLVQLLGVCTREPPFYIV 483
Query: 153 MEYMPGGDLVNLMSNYDVPEKW--ARFYTA-EVVLALDAIHSMGFIHRDVKPDNMLLDKS 209
E+MP G+L++ + + E A Y A ++ + + + FIHRD+ N L+ S
Sbjct: 484 TEFMPHGNLLDYLRSSTREENGPTALMYMATQIASGMAYLETKNFIHRDLAARNCLVADS 663
Query: 210 GHLKLADFGTCMKMNKEGMVRCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLY 269
+K+ADFG M + A + +PE L + D W+ GV L+
Sbjct: 664 NMVKVADFGLARLMKDDTYTAHIGAKFPIKWTAPEGLAFN----RFSTRSDIWAFGVLLW 831
Query: 270 EMLV-GDTPFYADSLVGTY 287
E+ G +P+ L Y
Sbjct: 832 ELATYGMSPYPGVELTEVY 888
>01060
Length = 1800
Score = 70.1 bits (170), Expect = 5e-12, Method: Compositional matrix adjust.
Identities = 64/219 (29%), Positives = 97/219 (44%), Gaps = 9/219 (4%)
Frame = +1
Query: 82 IGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAFFWEERDIMAF--ANSPWVVQL 139
IG G +G V RH++T + AMK K + D R+I +V L
Sbjct: 97 IGEGTYGVVYKCRHRATGRKLAMK---KIRLRGSEDGVPSSAIREIAMLRELRHTNIVCL 267
Query: 140 FYAFQDDRYLYMVMEYMPGGDLVNLMSNYDVPE------KWARFYTAEVVLALDAIHSMG 193
+D L++V E++ DL + + PE + + Y ++V + H
Sbjct: 268 EDVIMEDERLFLVFEFL-SMDLKMYIDKF--PEGVVLDRRLVKSYVFQIVTGIXFCHQRR 438
Query: 194 FIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTA-VGTPDYISPEVLKSQGGD 252
+HRD+KP N+L++ +G +K+ADFG M VR T V T Y +PE+L G
Sbjct: 439 IVHRDLKPQNLLINHTGAIKIADFG--MARTFALPVRAYTHEVVTLWYRAPEILM---GA 603
Query: 253 GYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIM 291
Y D WS+G +ML+ F DS + KI
Sbjct: 604 SKYSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIF 720
>18663
Length = 600
Score = 70.1 bits (170), Expect = 7e-12, Method: Composition-based stats.
Identities = 49/147 (33%), Positives = 70/147 (47%), Gaps = 11/147 (7%)
Frame = +2
Query: 233 TAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMN 292
T GTP+YI+PE+L+ + YG DWW++GV LYEML G +PF D + + N
Sbjct: 5 TFCGTPNYIAPEILRGED----YGFSVDWWALGVLLYEMLAGRSPF--DIAGASENPDQN 166
Query: 293 HKNSL-------TFPDDNDISKEAKNLICAFLTDREV-RLG---RNGVEEIKRHLFFKND 341
++ L T +S +A +++ FL RLG + +I H FFK
Sbjct: 167 TEDYLFQVILEKTIRIPRSLSVKAASVLKGFLNKNPADRLGCHRESAFMDIVNHPFFKVI 346
Query: 342 QWAWETLRDTVAPVVPDLSSDIDTSNF 368
W + P P L SD D +NF
Sbjct: 347 DWEMLERKQVSPPFKPRLDSDRDLANF 427
>19094
Length = 898
Score = 68.6 bits (166), Expect = 2e-11, Method: Composition-based stats.
Identities = 35/87 (40%), Positives = 53/87 (60%)
Frame = +1
Query: 189 IHSMGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPDYISPEVLKS 248
+HS IHRD+K N+LL+ GH KLADFG ++ + M + +T +GTP +++PEV++
Sbjct: 106 LHSRRKIHRDIKAGNILLNNEGHAKLADFGVAGQLT-DTMAKRNTVIGTPYWMAPEVIQE 282
Query: 249 QGGDGYYGRECDWWSVGVFLYEMLVGD 275
G Y D WS+G+ EM G+
Sbjct: 283 IG----YDCVADIWSLGITALEMAEGN 351
>26711
Length = 405
Score = 66.6 bits (161), Expect = 6e-11, Method: Composition-based stats.
Identities = 45/136 (33%), Positives = 67/136 (49%), Gaps = 3/136 (2%)
Frame = -2
Query: 181 EVVLALDAIHSMGFIHRDVKPDNMLL--DKSGHLKLADFGTCMKMNKEGMVRCDTAVGTP 238
+V+ L +H+ G +H D+KP N+LL DK ++L DFG K+ + GTP
Sbjct: 392 QVLDILQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARKLYPPQETFLNH--GTP 219
Query: 239 DYISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLT 298
+ SPE L + D W VGV Y +L G +PF ADS + K S
Sbjct: 218 GFTSPEALDVKP----ISTASDVWGVGVLAYILLSGQSPFQADSATESLKKTQTCDWSFD 51
Query: 299 F-PDDNDISKEAKNLI 313
P +++S++AK+ I
Sbjct: 50 VCPSFSNMSQDAKDFI 3
>21079
Length = 878
Score = 66.2 bits (160), Expect = 8e-11, Method: Composition-based stats.
Identities = 42/148 (28%), Positives = 76/148 (51%), Gaps = 4/148 (2%)
Frame = +1
Query: 134 PWVVQLFYAFQDDRYLYMVMEYMPGGDLVN--LMSNYDVPEKWARFYTAEVVLALDAIHS 191
P ++ L+ AF+ R + +VME++ G+L + ++ + E+ + ++ + +H+
Sbjct: 4 PKLLMLWDAFEAPRTMVLVMEFVGAGELFERVIRDDFVLTERDCVHFVRQICSGVGYMHT 183
Query: 192 MGFIHRDVKPDNMLL--DKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPDYISPEVLKSQ 249
+H D+KP+N+L D S +K+ DFG + K G GTP++I+PEV+
Sbjct: 184 QSILHLDLKPENVLCVSDNSNQIKIIDFGLA-RFYKPGD-SLQVLFGTPEFIAPEVVNYD 357
Query: 250 GGDGYYGRECDWWSVGVFLYEMLVGDTP 277
D WS+GV Y +L G +P
Sbjct: 358 ----EINFTTDMWSIGVICYILLSGLSP 429
>16708
Length = 1397
Score = 65.1 bits (157), Expect = 2e-10, Method: Composition-based stats.
Identities = 44/156 (28%), Positives = 78/156 (50%), Gaps = 15/156 (9%)
Frame = -1
Query: 78 VVKVIGRGAFGEVQLVRHKSTRKVYAMKL-------LSKFEMIKRSDSAFFWEERDIMAF 130
+++V+G+G FG+V R ST + A+K L + E + R + F+ +A
Sbjct: 1391 ILQVLGKGVFGKVYEARLLSTHEKAALKTSILCHHSLDEVEALGRIEGGFY------LAQ 1230
Query: 131 ANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNY---DVPEKWAR-----FYTAEV 182
WV L + + +++ + G L N+ ++Y ++P +W+ +
Sbjct: 1229 MFGAWVTCLPFP-----KMNILLHFYEMGPLCNVYAHYKNKEMPIRWSNPAMVCCIAGQX 1065
Query: 183 VLALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFG 218
V AL+ IH +G +H DVK DN+L+D G+ KL D+G
Sbjct: 1064 VCALEHIHELGVVHMDVKADNVLVDAHGNCKLTDYG 957
>14126
Length = 1265
Score = 61.6 bits (148), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 66/221 (29%), Positives = 93/221 (42%), Gaps = 14/221 (6%)
Frame = +3
Query: 76 YEVVKVIGRGAFGEVQLVRH-KSTRKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFAN-- 132
YE V VIG GA+G V R ++ + AMK + + + R+I
Sbjct: 195 YEEVAVIGNGAYGTVYKARDLRNQGEFVAMK---RIRLNNTEEGMPMMAIREISMLKQLE 365
Query: 133 ---SPWVVQLFYAFQD---DR--YLYMVMEYMPGGDLVNLMSNYDVPEKWA---RFYTAE 181
P VV+L + DR L +V EY+ DL ++ P + +
Sbjct: 366 QYEHPNVVRLLDVSHNTITDREIRLNLVFEYIEH-DLATYLAKCPSPGLGPDRIKDLMLQ 542
Query: 182 VVLALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPDYI 241
++ +D +HS +HRD+KP N+L+ K G LKLADFG + + T V T Y
Sbjct: 543 LLNGVDFLHSNRIVHRDLKPQNLLISKDGRLKLADFGLARIYSFH--MALTTVVVTLWYR 716
Query: 242 SPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADS 282
SPEVL YG D WS G E+ F S
Sbjct: 717 SPEVLMQ----AEYGTSVDIWSCGCIFAELFTRRALFKGSS 827
>21433
Length = 590
Score = 60.5 bits (145), Expect = 4e-09, Method: Composition-based stats.
Identities = 40/101 (39%), Positives = 54/101 (53%)
Frame = +2
Query: 178 YTAEVVLALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGT 237
Y ++ AL+ H IHRD+KP+N+LL G LK+ADFG + R T GT
Sbjct: 182 YIYQLSSALEYCHYRKVIHRDIKPENLLLGLKGDLKIADFGWSVHAPSS---RRTTMCGT 352
Query: 238 PDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPF 278
DY+ PE+++ + D D WS+GV YE LVG P
Sbjct: 353 LDYLPPEMVEGKTHD----ENVDLWSLGVLCYEFLVGTPPL 463
>04591
Length = 1117
Score = 60.5 bits (145), Expect = 5e-09, Method: Compositional matrix adjust.
Identities = 45/125 (36%), Positives = 62/125 (49%), Gaps = 2/125 (1%)
Frame = -2
Query: 149 LYMVMEYMPGGDLVNLMSNYDVPEKWA--RFYTAEVVLALDAIHSMGFIHRDVKPDNMLL 206
Y++ EY DL L++N V A + ++++ L IH+ +HRD+K N+LL
Sbjct: 972 FYLIFEYC-DYDLAGLLNNLRVKFSLADKKNLMSQLLNGLFYIHTKQILHRDIKAANILL 796
Query: 207 DKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGV 266
+ G LKLADFG K R V T Y PE+L G+ YG E D W VG
Sbjct: 795 TRDGVLKLADFGLSRPWVKSK--RLTNRVVTLWYRPPELLL---GEREYGPEIDMWGVGC 631
Query: 267 FLYEM 271
+ EM
Sbjct: 630 IMAEM 616
>25019
Length = 730
Score = 58.9 bits (141), Expect = 1e-08, Method: Composition-based stats.
Identities = 29/64 (45%), Positives = 39/64 (60%)
Frame = +3
Query: 202 DNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPDYISPEVLKSQGGDGYYGRECDW 261
+N+LLDK GH+KL DFG C K G T GT +Y++PE+L G +G+ DW
Sbjct: 261 ENVLLDKDGHVKLTDFGLC-KEAITGTRVTHTFCGTIEYMAPEILTRTG----HGKAVDW 425
Query: 262 WSVG 265
WS+G
Sbjct: 426 WSLG 437
>03508
Length = 1463
Score = 56.2 bits (134), Expect = 8e-08, Method: Compositional matrix adjust.
Identities = 39/118 (33%), Positives = 59/118 (50%), Gaps = 1/118 (0%)
Frame = +1
Query: 161 LVNLMSNYDVPEKWARFYTAEVVLALDAIHSMGFIHRDVKPDNMLLD-KSGHLKLADFGT 219
L ++YD+ RFY E++ ALD HSMG +HRDVKP N+++D ++ L+L D+G
Sbjct: 850 LYQTFTDYDI-----RFYLYELMKALDFCHSMGIMHRDVKPHNVMIDHENKKLRLIDWGL 1014
Query: 220 CMKMNKEGMVRCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTP 277
+ GM + V + + PE+L Y D WS+G M+ P
Sbjct: 1015A-EFYHPGM-EYNVRVASRYFKGPELLLDY---QMYDYSLDMWSLGCMFASMIFRKEP 1173
>17722
Length = 680
Score = 55.8 bits (133), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 38/109 (34%), Positives = 54/109 (49%), Gaps = 3/109 (2%)
Frame = -3
Query: 260 DWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLTFPDDNDISKEAKNLICAFLT- 318
DWW GV +YEM+ G PFY + I+ ++ FP ++S+EAK L+ L
Sbjct: 675 DWWGTGVVMYEMMCGRLPFYNRDHDVLFELIL--LQNVKFP--RNLSEEAKTLLSGLLAK 508
Query: 319 DREVRLGRN--GVEEIKRHLFFKNDQWAWETLRDTVAPVVPDLSSDIDT 365
+ + RLG + V EIK H FF+ W + P PD+ S DT
Sbjct: 507 NPKRRLGGSEADVTEIKTHPFFQCINWDDLAAKKITPPWKPDVKSSWDT 361
>11185
Length = 473
Score = 55.5 bits (132), Expect = 1e-07, Method: Composition-based stats.
Identities = 37/120 (30%), Positives = 53/120 (44%), Gaps = 21/120 (17%)
Frame = +1
Query: 176 RFYTAEVVLALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTCMK------------- 222
R + +V L IHS+G + D++P +LLD SG LK ADFG
Sbjct: 10 RDFGIHLVTGLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFA 189
Query: 223 --------MNKEGMVRCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVG 274
+ E M++ G+P Y++PEV QG + D W++G YEM G
Sbjct: 190 EAGDQWNIQSAEEMMKQVPTSGSPTYMAPEVF--QGAEPSI--MSDLWALGCVFYEMFSG 357
>29581
Length = 1278
Score = 55.5 bits (132), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 43/132 (32%), Positives = 61/132 (46%), Gaps = 2/132 (1%)
Frame = -2
Query: 149 LYMVMEYMPGGDLVNLMSNYDVP--EKWARFYTAEVVLALDAIHSMGFIHRDVKPDNMLL 206
L++VMEY DL +L+ N P E + +++ L +H IHRD+K N+L+
Sbjct: 1124 LFLVMEYC-EQDLASLLDNMPAPFSESQVKCIVLQLLKGLRYLHEAFIIHRDLKVSNLLM 948
Query: 207 DKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGV 266
G +K+ADFG K V T Y +PE+L G + D WS G
Sbjct: 947 TDKGCVKIADFGLARNYGKPQKPMTPKVV-TLWYRAPELL---FGSKTHSTAIDMWSAGC 780
Query: 267 FLYEMLVGDTPF 278
L E+L G P
Sbjct: 779 ILGELL-GHKPL 747
>19761
Length = 473
Score = 55.5 bits (132), Expect = 2e-07, Method: Composition-based stats.
Identities = 31/104 (29%), Positives = 53/104 (50%), Gaps = 2/104 (1%)
Frame = -3
Query: 170 VPEKWARFYTAEVVLALDAIHSMG--FIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEG 227
+PE+ + + AL+ +H+ +HRD+KP N+ + + G ++L D G K+
Sbjct: 432 LPERLIVCWLMQTASALNYMHTHTPVILHRDLKPQNIYVTEKGDVRLGDLGLARKLTGPA 253
Query: 228 MVRCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEM 271
+ VGT Y+SPE+L Q Y + D WS+G Y++
Sbjct: 252 DF-ATSQVGTIMYLSPEILSQQP----YNSKSDIWSLGCVFYDI 136
>27546
Length = 426
Score = 52.8 bits (125), Expect = 9e-07, Method: Composition-based stats.
Identities = 29/100 (29%), Positives = 54/100 (54%), Gaps = 1/100 (1%)
Frame = -1
Query: 120 FFWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVN-LMSNYDVPEKWARFY 178
FF E +I+ + P ++Q+ Q +++ M Y GD+++ + + E + +
Sbjct: 342 FFPRELEILTRLDHPNIIQIHSILQRGPKIFIFMRYAEKGDMLSHIKKTGPIDEAQTKVW 163
Query: 179 TAEVVLALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFG 218
++ AL +HS HRD+K +N+LL K ++K+ADFG
Sbjct: 162 FFQMAKALQYLHSHDIAHRDLKCENILLSKRLNVKIADFG 43
>00392
Length = 668
Score = 50.8 bits (120), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 40/171 (23%), Positives = 80/171 (46%), Gaps = 13/171 (7%)
Frame = +3
Query: 121 FWEERDIMAFANSPWVVQLF-----YAFQDDRYLYMVMEYMPGGDLVNLMSNYDVP---- 171
F EE +++ P +V+ F + ++ + + +V E M G L + + P
Sbjct: 72 FKEEAEMLKELQHPNIVRFFDYWEEHNHRNRKVIILVTELMTSGTLKTYLKRFKKPNVKI 251
Query: 172 -EKWARFYTAEVVLALDAIHSMG--FIHRDVKPDNMLL-DKSGHLKLADFGTCMKMNKEG 227
+ W R +V+ L +H+ IHRD+K DN+ + +G +K+ D G N+
Sbjct: 252 LKNWCR----QVLKGLYFLHTRTPPVIHRDLKCDNIFITGPTGSVKIGDLGLATLKNQSF 419
Query: 228 MVRCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPF 278
+ +GTP++++PE+ + +Y D ++ G+ + EM + P+
Sbjct: 420 A---KSVIGTPEFMAPEMYEE-----HYDEAVDVYAFGMCMLEMASSEYPY 548
>28157
Length = 400
Score = 50.4 bits (119), Expect = 5e-06, Method: Composition-based stats.
Identities = 35/107 (32%), Positives = 57/107 (53%), Gaps = 8/107 (7%)
Frame = +3
Query: 121 FWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKW----AR 176
F +E ++ + P +V L+ A +D + +VMEY GG L N++ ++ A
Sbjct: 51 FMQELKQLSRVSHPNIVCLYGACRD-HPVCLVMEYAEGGSLYNVLHGSGPQPQYTAAHAM 227
Query: 177 FYTAEVVLALDAIHSM---GFIHRDVKPDNMLLDKSG-HLKLADFGT 219
+ + L ++ +H M IHRD+KP N+LL + G LK+ DFGT
Sbjct: 228 NWLLQCALGVEYLHGMKPKALIHRDLKPPNLLLIQCGTKLKICDFGT 368
>00715
Length = 1788
Score = 48.5 bits (114), Expect = 2e-05, Method: Composition-based stats.
Identities = 38/162 (23%), Positives = 70/162 (43%), Gaps = 23/162 (14%)
Frame = +1
Query: 140 FYAFQDDRYLYMVMEYMPGGDLVNLMSNY--DVPEKWARFYTAEVVLALDAIHSMGFIHR 197
+ F+D +L MEY+ +L +++++ D+ ++ L +HS+ +H
Sbjct: 139 LHRFEDGAWL--AMEYVGPLNLQTILNDHQQDIDSSMRLSLALQMARGLHYLHSINIVHL 312
Query: 198 DVKPDNMLLDKSGHLKLADFGTCMKMNKEGM---------------------VRCDTAVG 236
D+KP N LL + L++ADFG C ++ G+ + G
Sbjct: 313 DLKPANCLLTRDLKLRIADFGCCHQLTPTGLDMGEREGGMAGNELELTPVQGAWKNELAG 492
Query: 237 TPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPF 278
T Y +PE+LK D +S+G+ L++M P+
Sbjct: 493 TLAYRAPELLKGLQPS----VRSDVYSLGITLWQMCTRQGPY 606
>04138
Length = 800
Score = 48.5 bits (114), Expect = 2e-05, Method: Composition-based stats.
Identities = 33/85 (38%), Positives = 40/85 (47%), Gaps = 2/85 (2%)
Frame = +1
Query: 189 IHSMGFIHRDVKPDNMLLDKSGHLKLADFG--TCMKMNKEGMVRCDTAVGTPDYISPEVL 246
IH +HRD+K N+L+ K G LKLADFG +N R V T Y PE+L
Sbjct: 61 IHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRPPELL 240
Query: 247 KSQGGDGYYGRECDWWSVGVFLYEM 271
GD Y D W G + EM
Sbjct: 241 L---GDRNYSTAIDQWGAGCIMAEM 306
>01966
Length = 1735
Score = 48.1 bits (113), Expect = 2e-05, Method: Composition-based stats.
Identities = 46/162 (28%), Positives = 75/162 (46%), Gaps = 9/162 (5%)
Frame = -1
Query: 94 RHKSTRKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFAN--SPWVVQLFYAFQDDRYLYM 151
RH++T + AMK K + D R+I +V L +D L++
Sbjct: 1651 RHRATGRKLAMK---KIRLRGSEDGVPSSAIREIAMLRELRHTNIVCLEDVIMEDERLFL 1481
Query: 152 VMEYMPGGDLVNLMSNYDVPE------KWARFYTAEVVLALDAIHSMGFIHRDVKPDNML 205
V E++ DL + + PE + + Y ++V ++ H +HRD+KP N+L
Sbjct: 1480 VFEFL-SMDLKMYIDKF--PEGVVLDRRLVKSYVFQIVTGINFCHQRRIVHRDLKPQNLL 1310
Query: 206 LDKSGHLKLADFGTCMKMNKEGMVRCDT-AVGTPDYISPEVL 246
++ +G +K+ADFG M VR T V T Y +PE+L
Sbjct: 1309 INHTGAIKIADFG--MARTFALPVRAYTHEVVTLWYRAPEIL 1190
>19301
Length = 712
Score = 47.4 bits (111), Expect = 4e-05, Method: Compositional matrix adjust.
Identities = 22/70 (31%), Positives = 43/70 (61%), Gaps = 1/70 (1%)
Frame = +2
Query: 151 MVMEYMPGGDLVNLMSNY-DVPEKWARFYTAEVVLALDAIHSMGFIHRDVKPDNMLLDKS 209
++MEY P G L ++ + ++P ++ ++ ++ +HS IHRD+K N+L+ K+
Sbjct: 500 IIMEYCPYGQLYEVLRDGKEIPPALVLDWSKQIASGMNYLHSHKIIHRDLKSPNVLVAKN 679
Query: 210 GHLKLADFGT 219
+K++DFGT
Sbjct: 680 DVVKISDFGT 709
>37063
Length = 455
Score = 47.4 bits (111), Expect = 4e-05, Method: Composition-based stats.
Identities = 27/78 (34%), Positives = 45/78 (57%), Gaps = 8/78 (10%)
Frame = -2
Query: 199 VKPDNML---LDKSGHLKLADFGTCMKMNKEG----MVRCDTAVGTPDYISPEVLKSQGG 251
+KP+N+L LD+ LK+ DF +N +G T VG+ +Y++PEV+ + G
Sbjct: 454 LKPENILCEHLDEVVPLKICDFDLASGINCDGDGTKTPELLTPVGSAEYMAPEVVDAWVG 275
Query: 252 DGY-YGRECDWWSVGVFL 268
+ + Y + CD WS+G+ L
Sbjct: 274 ESFSYDKRCDMWSLGIIL 221
>14116
Length = 1017
Score = 47.4 bits (111), Expect = 4e-05, Method: Compositional matrix adjust.
Identities = 36/126 (28%), Positives = 63/126 (50%), Gaps = 4/126 (3%)
Frame = -1
Query: 151 MVMEYMPGGDLVNLMSN--YDVPEKWARFYTAEVVLALDAIHSMGFIHRDVKPDNMLLDK 208
+V+ +M GDL+ + + + K Y ++ +D + + F+HRD+ N +LD+
Sbjct: 393 VVLPFMKHGDLLTYIRDDQHQPTIKDLIMYGVDIARGMDYLAGLKFVHRDLAARNCMLDE 214
Query: 209 SGHLKLADFGTCMKM-NKEGMVRCDTAVGTP-DYISPEVLKSQGGDGYYGRECDWWSVGV 266
H+K+ADFG + KE + P +++ E L+ G Y + D WS GV
Sbjct: 213 DFHVKVADFGLARDIYEKEYYSSENKKAKLPVKWMALESLEK----GNYDSKTDVWSYGV 46
Query: 267 FLYEML 272
L+E+L
Sbjct: 45 VLWELL 28
>37602
Length = 804
Score = 46.2 bits (108), Expect = 9e-05, Method: Composition-based stats.
Identities = 28/86 (32%), Positives = 43/86 (50%), Gaps = 5/86 (5%)
Frame = -1
Query: 137 VQLFYAFQDD----RYLYMVMEYMPGGDLVNLMS-NYDVPEKWARFYTAEVVLALDAIHS 191
+Q F + D L++ MEY GG + ++ + E F E + L +H
Sbjct: 342 IQTFVGYFDSYLRREKLWIAMEYCGGGSMQDIYHVTGPLTEPQIAFVCRETLKGLHYLHR 163
Query: 192 MGFIHRDVKPDNMLLDKSGHLKLADF 217
G +HRD+K N+LL + G +KLADF
Sbjct: 162 RGKMHRDIKGANILLTEEGDVKLADF 85
>21808
Length = 1011
Score = 45.4 bits (106), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 41/165 (24%), Positives = 69/165 (41%), Gaps = 7/165 (4%)
Frame = +1
Query: 121 FWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKWARFY-- 178
F E IM P ++QL+ D ++++ E M G L+ + K
Sbjct: 73 FLAEAQIMKKLRHPKLIQLYAVCTQDDPIFIITELMKNGSLLEFLQGKGRVLKLPALIDI 252
Query: 179 TAEVVLALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGTP 238
A++ + + S +IHRD+ N+L+ + +K+ADFG ++ KE P
Sbjct: 253 GAQIACGMAYLESQNYIHRDLAARNILVSDNNTVKIADFGLA-RVIKEDEYEARVGARFP 429
Query: 239 -DYISPEVLKSQGGDGYYGR---ECDWWSVGVFLYEMLV-GDTPF 278
+ +PE Y R + D WS G+ L E + G P+
Sbjct: 430 IKWTAPEAAN-------YNRFTIKSDVWSFGILLTETVTYGRVPY 543
>07940
Length = 1336
Score = 44.3 bits (103), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 32/103 (31%), Positives = 51/103 (49%), Gaps = 2/103 (1%)
Frame = -3
Query: 178 YTAEVVLALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGT 237
Y +V ++ + S IHRD+ N+L+ + LK+ADFG + + R T
Sbjct: 332 YAYQVARGMEYLASKQCIHRDLAARNVLVAEEYVLKIADFGLTRNLQQFDYYRKTTDGRL 153
Query: 238 P-DYISPEVLKSQGGDGYYGRECDWWSVGVFLYEML-VGDTPF 278
P +++PE L D Y + D WS GV L+E+ +G P+
Sbjct: 152 PVKWMAPEALF----DRKYTSKSDVWSYGVLLWEIFTLGGNPY 36
>07833
Length = 1504
Score = 43.9 bits (102), Expect = 4e-04, Method: Composition-based stats.
Identities = 37/169 (21%), Positives = 73/169 (43%), Gaps = 11/169 (6%)
Frame = -3
Query: 121 FWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLM---SNYDVPEKWARF 177
F EE + N P V+ + L ++ ++MP G L N + S V + +
Sbjct: 1478 FMEEFPRLRIFNHPNVLPVLACCNQPPNLVLISQFMPFGSLYNTLHGESGIVVDQNQSLR 1299
Query: 178 YTAEVVLALDAIHSMGFIHRDVKPDNMLLDK--------SGHLKLADFGTCMKMNKEGMV 229
+ ++ ++ +HSM P+ +L K + + +AD+ C +++G V
Sbjct: 1298 FAMDIARGMEFLHSM----EPTIPNFLLTSKHVMIDEDLTARINMADY--CFSFHEKGKV 1137
Query: 230 RCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPF 278
+P +++PE L+ + D R D WS + ++E+ + PF
Sbjct: 1136 Y------SPAWMAPEALQRRPDD-INTRAADMWSFAILMWELETREVPF 1011
>32359
Length = 928
Score = 34.3 bits (77), Expect(2) = 5e-04, Method: Compositional matrix adjust.
Identities = 33/131 (25%), Positives = 59/131 (45%), Gaps = 11/131 (8%)
Frame = -1
Query: 76 YEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSPW 135
Y KVIG G+FG V + T ++ A+K + + D F E IM
Sbjct: 424 YTDAKVIGNGSFGVVYQAKLVDTSELVAIKKVLQ-------DKRFKNRELQIMRKLEHQN 266
Query: 136 VVQLFYAF------QDDRYLYMVMEYMPGGDLVNLMSNYD-----VPEKWARFYTAEVVL 184
+V+L + F +D+ +L +V+EY+P + + +Y +P + + Y ++
Sbjct: 265 IVKLKFFFYSSGEKKDEVFLNLVLEYVP-ETVYRVARHYSKSKQTIPILYIKLYMYQLFR 89
Query: 185 ALDAIHSMGFI 195
+L IHS +
Sbjct: 88 SLAYIHSQACV 56
Score = 28.5 bits (62), Expect(2) = 5e-04, Method: Composition-based stats.
Identities = 10/15 (66%), Positives = 12/15 (80%)
Frame = -3
Query: 193 GFIHRDVKPDNMLLD 207
G HRD+KP N+LLD
Sbjct: 65 GVCHRDIKPQNLLLD 21
>06358
Length = 1517
Score = 43.5 bits (101), Expect = 6e-04, Method: Compositional matrix adjust.
Identities = 47/171 (27%), Positives = 72/171 (42%), Gaps = 14/171 (8%)
Frame = +3
Query: 123 EERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKWARFYTAEV 182
E R+ +AFA P L D + V + + L YDV K E
Sbjct: 237 ESRETLAFATEPVFASLANVLGDLSSIXTVPKELQDYQL------YDVEIKHGLLQVTE- 395
Query: 183 VLALDAIHS-MGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMV---------RCD 232
AL +H+ +HR+V P+ ++L K G KLA + C++ + R D
Sbjct: 396 --ALGFLHNDAKMMHRNVCPEAIMLTKLGSWKLAGYEFCVRSSDPQSTDPSYPFYEWRSD 569
Query: 233 TA-VGTP--DYISPE-VLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFY 279
A V P D+++PE VL Q G G D +S+G+ +Y + P +
Sbjct: 570 IAPVTQPHLDFMAPEYVLTMQCGTG-----SDMFSLGLLVYSVFAKGKPLF 707
>32957
Length = 645
Score = 43.1 bits (100), Expect = 8e-04, Method: Composition-based stats.
Identities = 18/43 (41%), Positives = 28/43 (65%)
Frame = +3
Query: 230 RCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEML 272
R T GT +Y++PEV + + YG+E DWW +G+ L+E+L
Sbjct: 33 RTRTFCGTREYMAPEVHERK----EYGKEVDWWGLGILLHELL 149
>00638
Length = 1595
Score = 43.1 bits (100), Expect = 8e-04, Method: Composition-based stats.
Identities = 23/60 (38%), Positives = 35/60 (58%), Gaps = 3/60 (5%)
Frame = +2
Query: 151 MVMEYMPGGDLVNL---MSNYDVPEKWARFYTAEVVLALDAIHSMGFIHRDVKPDNMLLD 207
++ E++ D L ++YD+ RFY E++ ALD HSMG +HRDVKP L++
Sbjct: 356 LIFEHVNNTDFKQLYQTFTDYDI-----RFYLYELMKALDFCHSMGIMHRDVKPSPPLVN 520
>14748
Length = 606
Score = 42.7 bits (99), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 35/111 (31%), Positives = 63/111 (56%)
Frame = +3
Query: 527 KKVSQNSQLANEKLSQLQKQLEEANDLLRTESDTAVRLRKSHTEMSKSISQLESLNRELQ 586
++++++S ++E+L+ ++K L EAN LRTE D A + +K+ ++M + + E EL
Sbjct: 231 QEINRDSVQSSERLASVEKSLNEANVKLRTEMDHANKQKKAMSDMQQRLMNAEQNYGELT 410
Query: 587 ERNRILENSKSQTDKDYYQLQAILEAERRDRGHDSEMIGDLQARITSLQEE 637
R + L K + + + LQA L+ ER R + +L RI +LQ+E
Sbjct: 411 GRYQDLNALKQRMETEVLTLQASLDVERNARSQEVAHTMELNERIKALQDE 563
>12672
Length = 773
Score = 42.4 bits (98), Expect = 0.001, Method: Composition-based stats.
Identities = 27/85 (31%), Positives = 41/85 (48%), Gaps = 3/85 (3%)
Frame = +3
Query: 193 GFIHRDVKPDNMLLDKSGHLKLADFGTCMKM-NKEGMV--RCDTAVGTPDYISPEVLKSQ 249
G +HRD+K N+LLD K+ DF T + + EG +GT Y++PE +
Sbjct: 51 GHVHRDIKTANILLDSEYTAKVGDFATVVSAPSGEGKTVQNASVVIGTAAYLAPEAIHFD 230
Query: 250 GGDGYYGRECDWWSVGVFLYEMLVG 274
+ D +S GV L E++ G
Sbjct: 231 -----VSTKLDSYSFGVVLLEVITG 290
>04852
Length = 1462
Score = 42.4 bits (98), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 40/151 (26%), Positives = 71/151 (47%), Gaps = 6/151 (3%)
Frame = +1
Query: 157 PGGDLV---NLMSNYDVPEKWARFYTAEVVLALDAIHSMGFIHRDVKPDNMLLDKSGHLK 213
PGG ++ NL+S Y ++ ++ + S IHRD+ N+L+ + LK
Sbjct: 301 PGGHVIRRKNLLS-----------YAFQIARGMEFLASRKCIHRDLAARNVLVTEEHVLK 447
Query: 214 LADFGTCMKMNKEGMVRCDTAVG--TPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEM 271
+ADFG +++ G + G +++PE L D Y + D WS GV L+E+
Sbjct: 448 IADFG----LSRTGDYYKKRSGGRLPVKWMAPEALF----DMRYTTKSDVWSFGVVLWEI 603
Query: 272 L-VGDTPFYADSLVGTYSKIMNHKNSLTFPD 301
+G P+ + YSK+++ + P+
Sbjct: 604 FSLGGMPYASIPNEELYSKLLDDAYRMPRPE 696
>29590
Length = 320
Score = 42.0 bits (97), Expect = 0.002, Method: Composition-based stats.
Identities = 23/55 (41%), Positives = 30/55 (54%)
Frame = +3
Query: 235 VGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSK 289
+GTPDY++PEVL + + D WS+GV Y ML +PF VG SK
Sbjct: 57 IGTPDYVAPEVLDYEP----LSIQTDMWSLGVLSYVMLTACSPF-----VGITSK 194
>11780
Length = 1713
Score = 41.6 bits (96), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 36/151 (23%), Positives = 74/151 (49%), Gaps = 3/151 (1%)
Frame = +3
Query: 71 MKAEDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAFFWEERDIMAF 130
+ +D E+ + IG+G FG+V ++ + A+K L + ++S F +E +M
Sbjct: 588 IAXQDLEIGEAIGKGDFGDVYKGMYRG--QPVAIKQLKDKDRGEQS----FLQEASVMTS 749
Query: 131 ANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYD---VPEKWARFYTAEVVLALD 187
+V+L + +++V E+M G+LV + + + +K + + A++
Sbjct: 750 LRHDNLVRLIGVVLGET-IFLVTEFMGKGNLVEYLRSRGRSVITKKDQINFATDTCAAME 926
Query: 188 AIHSMGFIHRDVKPDNMLLDKSGHLKLADFG 218
+ S +HRD+ N+L+ G K++DFG
Sbjct: 927 YLESKRLVHRDLAARNVLVHDDGKAKVSDFG 1019
>18996
Length = 491
Score = 40.4 bits (93), Expect = 0.005, Method: Composition-based stats.
Identities = 29/85 (34%), Positives = 44/85 (51%), Gaps = 2/85 (2%)
Frame = +2
Query: 195 IHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGTP-DYISPEVLKSQGGDG 253
IHRD+ N+L+D+S +K++DFG N +G + P + SPE +++
Sbjct: 2 IHRDLAARNILVDRSC-VKISDFGLAQFANADGYYYGISQRDIPIKWYSPEAIETCKFSS 178
Query: 254 YYGRECDWWSVGVFLYEMLV-GDTP 277
Y D WS GV L+EM G+ P
Sbjct: 179 Y----SDVWSYGVTLFEMFSRGEIP 241
>02638
Length = 1490
Score = 40.4 bits (93), Expect = 0.005, Method: Composition-based stats.
Identities = 21/66 (31%), Positives = 34/66 (51%)
Frame = +1
Query: 235 VGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHK 294
+GT +++PEVL+ + YGR CD WSVG + EM P+ + + + I
Sbjct: 19 LGTIAFMAPEVLRGES----YGRACDVWSVGCVMIEMCTCRPPWNSHDISNHLALIFKIA 186
Query: 295 NSLTFP 300
+S+ P
Sbjct: 187 SSVDPP 204
>17300
Length = 480
Score = 40.0 bits (92), Expect = 0.007, Method: Composition-based stats.
Identities = 25/99 (25%), Positives = 48/99 (48%), Gaps = 4/99 (4%)
Frame = +1
Query: 185 ALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGTP---DYI 241
+ + MG++HRD+ N+L+++ K+ADFG ++ + T G +
Sbjct: 10 GMGXLADMGYVHRDLAARNILVNEILVCKVADFGLSREIESDTTEGAYTTKGGKIPVRWT 189
Query: 242 SPEVLKSQGGDGYYGRECDWWSVGVFLYE-MLVGDTPFY 279
+PE + + + D WS GV ++E M G+ P++
Sbjct: 190 APEAIAYRK----FTSASDVWSFGVVMWEVMSYGERPYW 294
>07291
Length = 833
Score = 39.7 bits (91), Expect = 0.009, Method: Compositional matrix adjust.
Identities = 22/87 (25%), Positives = 45/87 (51%), Gaps = 3/87 (3%)
Frame = +1
Query: 195 IHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCD--TAVGTPDYISPEVLKSQGGD 252
+HR++ N ++ + G L+L+D+G + + D A +++PE + +
Sbjct: 115 VHRNLAARNCIVTEDGRLQLSDYGVTGSLFPQSYYTADDSPARDLVKWMAPETID----N 282
Query: 253 GYYGRECDWWSVGVFLYEMLV-GDTPF 278
++ + D W+ GV L+E+L G TP+
Sbjct: 283 FHFSSKSDVWAFGVVLWELLTRGITPY 363
>11404
Length = 563
Score = 38.9 bits (89), Expect = 0.013, Method: Compositional matrix adjust.
Identities = 39/153 (25%), Positives = 68/153 (44%), Gaps = 19/153 (12%)
Frame = +1
Query: 73 AEDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSK--------------FEMIKRSDS 118
A+ YE+ +IG+G+FG+V + + A+K++ EM+ R D+
Sbjct: 136 ADRYEIDSLIGKGSFGQVVKAYDHTDNEQVAIKIIKNKKPFLNQAQIEVKLLEMMNRHDT 315
Query: 119 AFFWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYD---VPEKWA 175
N ++V+L F +L +V E + +L +L+ N + V
Sbjct: 316 ------------DNKYYIVRLKRHFMFRSHLCLVFELL-SYNLYDLLRNTNFRGVSLNLT 456
Query: 176 RFYTAEVVLAL--DAIHSMGFIHRDVKPDNMLL 206
R + ++ AL A M IH D+KP+N+LL
Sbjct: 457 RKFAQQLCTALLFLATPEMSIIHCDLKPENILL 555
>13840
Length = 446
Score = 38.9 bits (89), Expect = 0.015, Method: Compositional matrix adjust.
Identities = 38/134 (28%), Positives = 59/134 (44%), Gaps = 7/134 (5%)
Frame = -1
Query: 73 AEDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMK-LLSKFEMIKRSDSAFFWEERDIMAFA 131
+ED + + IGRG +G V +RHK T V A+K + S E +R + +M
Sbjct: 398 SEDMQDMGEIGRGNYGTVNKMRHKITSTVMAVKRIRSTVE--EREQKQLLMDLDVVMRSN 225
Query: 132 NSPWVVQLFYAFQDDRYLYMVMEYMPGG-----DLVNLMSNYDVPEKWARFYTAEVVLAL 186
N P++VQ + A + ++ ME M V +PE T + AL
Sbjct: 224 NCPFIVQFYGALFKEGDCWICMELMETSLDKFYKFVYGEMQSSIPENILGKITVATLKAL 45
Query: 187 DAI-HSMGFIHRDV 199
+ + + IHRDV
Sbjct: 44 NYLKEELRIIHRDV 3
>33586
Length = 551
Score = 38.9 bits (89), Expect = 0.015, Method: Composition-based stats.
Identities = 19/49 (38%), Positives = 32/49 (65%), Gaps = 1/49 (2%)
Frame = +2
Query: 135 WVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDV-PEKWARFYTAEV 182
++V L YAFQ + LY+++E++ GGDL +S + E+ +FY AE+
Sbjct: 404 FIVHLHYAFQTEGKLYLILEFLRGGDLFTRLSKEVMFTEEDVKFYLAEL 550
>18401
Length = 463
Score = 38.5 bits (88), Expect = 0.017, Method: Compositional matrix adjust.
Identities = 18/46 (39%), Positives = 24/46 (52%)
Frame = -3
Query: 233 TAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPF 278
T V T Y +PEV+ G + CD WSVG ++E+ G T F
Sbjct: 455 TIVSTRHYRAPEVILELG----WSHPCDVWSVGCIMFELYTGYTLF 330
>29360
Length = 363
Score = 38.5 bits (88), Expect = 0.021, Method: Compositional matrix adjust.
Identities = 22/72 (30%), Positives = 37/72 (51%), Gaps = 2/72 (2%)
Frame = +3
Query: 137 VQLFYAFQDDRYLYMVMEYMPGG--DLVNLMSNYDVPEKWARFYTAEVVLALDAIHSMGF 194
V+ F FQ + +V E + D + +P K+ R T +V+ AL + +G
Sbjct: 144 VRAFECFQHKNHTCLVFEMLEQNLYDFLKQNKFQPLPLKYIRPITQQVLTALRKLKQLGL 323
Query: 195 IHRDVKPDNMLL 206
IH D+KP+N++L
Sbjct: 324 IHADLKPENIML 359
>20152
Length = 445
Score = 37.4 bits (85), Expect = 0.041, Method: Composition-based stats.
Identities = 20/50 (40%), Positives = 28/50 (56%)
Frame = +1
Query: 243 PEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMN 292
PE+L GD Y D WS+GV LY ++VG+ PF + T + IM+
Sbjct: 1 PEILL---GDSYDAPAVDVWSLGVILYMLVVGEAPFQEANDSETLTMIMD 141
>25829
Length = 543
Score = 37.0 bits (84), Expect = 0.048, Method: Compositional matrix adjust.
Identities = 39/126 (30%), Positives = 60/126 (47%)
Frame = +3
Query: 536 ANEKLSQLQKQLEEANDLLRTESDTAVRLRKSHTEMSKSISQLESLNRELQERNRILENS 595
AN + SQLQ Q E++ LR + VRL + +S+ + LE + L E R L++
Sbjct: 123 ANSRCSQLQNQDAESSRELRNLTRQHVRLEEEKKHLSRDYATLEQKMQLLTEEKRQLQDQ 302
Query: 596 KSQTDKDYYQLQAILEAERRDRGHDSEMIGDLQARITSLQEEVKHLKHNLEKVEGERKEA 655
++T K+ +LQ +E DRG S SLQ+++ + L KV+G K
Sbjct: 303 LAETKKEVSRLQECME----DRGKSS----------VSLQDKLTAAEKELSKVKGPMKRH 440
Query: 656 QDMLNH 661
D H
Sbjct: 441 PDPPGH 458
>18481
Length = 437
Score = 37.0 bits (84), Expect = 0.049, Method: Composition-based stats.
Identities = 28/114 (24%), Positives = 50/114 (43%), Gaps = 4/114 (3%)
Frame = -1
Query: 109 KFEMIKRSDSAFFWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYM-PGGDLVNLMSN 167
K E I +E + P + +++ + + +VME + P + + ++
Sbjct: 392 KIEAIDVKHQLLHYEAKVYEQIGRHPGLPTMYHYGTEKHFNALVMELLGPSLEELFVICK 213
Query: 168 YDVPEKWARFYTAEVVLALDAIHSMGFIHRDVKPDNMLLDKSGH---LKLADFG 218
K + +++ L+ IH FIHRD+KPDN L+ H L + DFG
Sbjct: 212 RRFTLKTILMVSDQLLSRLEFIHQKCFIHRDLKPDNFLMGLGRHCHRLYIIDFG 51
>26009
Length = 886
Score = 36.2 bits (82), Expect = 0.081, Method: Compositional matrix adjust.
Identities = 17/36 (47%), Positives = 23/36 (63%)
Frame = +2
Query: 74 EDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSK 109
E Y+V K +GRG +G+V L R + T A+KLL K
Sbjct: 416 EHYDVCKELGRGTYGKVVLARCRHTGTQVALKLLPK 523
Score = 35.0 bits (79), Expect = 0.20, Method: Composition-based stats.
Identities = 14/32 (43%), Positives = 23/32 (71%)
Frame = +3
Query: 175 ARFYTAEVVLALDAIHSMGFIHRDVKPDNMLL 206
A+ ++V ALD +HS +HRD+KP+N+L+
Sbjct: 717 AKSVMKQLVSALDFMHSKQLVHRDIKPENVLI 812
>31489
Length = 329
Score = 36.2 bits (82), Expect = 0.086, Method: Composition-based stats.
Identities = 20/67 (29%), Positives = 39/67 (58%), Gaps = 1/67 (1%)
Frame = +3
Query: 140 FYAFQDDRYLYMVMEYMPGGDLVNLM-SNYDVPEKWARFYTAEVVLALDAIHSMGFIHRD 198
++ F+D ++ +ME DL ++ S+ + E+ R++ +++ L IHS +HRD
Sbjct: 75 YHDFKDIHVVFDLME----SDLHRIIYSDQPLTEEHIRYFLYQILRGLKYIHSANVVHRD 242
Query: 199 VKPDNML 205
+KP N+L
Sbjct: 243 LKPSNLL 263
>01106
Length = 878
Score = 35.8 bits (81), Expect = 0.11, Method: Compositional matrix adjust.
Identities = 37/146 (25%), Positives = 70/146 (47%), Gaps = 15/146 (10%)
Frame = +3
Query: 76 YEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAF-------FWEERDIM 128
Y V++ +G G F V L + ++ A+K++ + +++A E D+
Sbjct: 324 YHVIRKLGWGHFSTVWLCWDLTCKRFVALKVVKSAQ--HYTETALDEVKLLKCVRESDVA 497
Query: 129 AFANSPWVVQLFYAFQ----DDRYLYMVMEYMPGGDLVNLM--SNY-DVPEKWARFYTAE 181
A + VQL F+ + ++ MV E + G +L+ L+ SNY +P + +
Sbjct: 498 DPARAK-CVQLLDDFKISGVNGTHVAMVFEVL-GYNLLKLIIRSNYQGIPIHNVKLIIRQ 671
Query: 182 VVLALDAIHS-MGFIHRDVKPDNMLL 206
V+ L +H+ IH D+KP+N+L+
Sbjct: 672 VLEGLSYMHAKCRIIHTDIKPENILI 749
>17516
Length = 453
Score = 33.1 bits (74), Expect = 0.71, Method: Composition-based stats.
Identities = 16/42 (38%), Positives = 25/42 (59%)
Frame = -3
Query: 233 TAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVG 274
T GTP Y++PEVL + G Y + D +S+ + L+E+ G
Sbjct: 442 TLAGTPVYMAPEVLLQK---GQYDMKADVYSLAIILWELWYG 326
>28040
Length = 433
Score = 32.7 bits (73), Expect = 0.99, Method: Compositional matrix adjust.
Identities = 45/124 (36%), Positives = 68/124 (54%), Gaps = 5/124 (4%)
Frame = +3
Query: 569 TEMSKSISQLESLNRELQERNRILENSKSQTDKDYYQLQAILEAERRDRGHDSEMIGDLQ 628
++MS +S +ESL L R+ LE SQT+ QL+ L +ER + E+ G LQ
Sbjct: 24 SQMSSMLSTMESLQGTLSARDSELEQLMSQTE----QLKEKL-SEREE-----EVTG-LQ 170
Query: 629 ARITSLQEEVKHLKHNLEKV-EGERKEAQDM---LNHSEKEKNNLEIDLNY-KLKSLQQR 683
A + SLQ+ + K +LE V E AQD+ ++ EK ++ LE +L K K+L+Q+
Sbjct: 171 ASLGSLQDVIAMTKSDLEAVTEDYNDRAQDLEAQISELEKRRDQLETELETEKAKNLEQK 350
Query: 684 LEQE 687
E E
Sbjct: 351 EELE 362
>27274
Length = 396
Score = 32.7 bits (73), Expect = 1.1, Method: Composition-based stats.
Identities = 17/56 (30%), Positives = 30/56 (53%), Gaps = 8/56 (14%)
Frame = -1
Query: 244 EVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPF--------YADSLVGTYSKIM 291
E+L+ Q +G D WS+G+ L+E+L G PF A +++ Y++I+
Sbjct: 375 ELLRGQ----QHGPTVDMWSLGILLHELLSGHVPFEPERGSRQMARNMMAVYAQII 220
>20640
Length = 1492
Score = 32.3 bits (72), Expect = 1.3, Method: Composition-based stats.
Identities = 23/91 (25%), Positives = 40/91 (43%), Gaps = 3/91 (3%)
Frame = +1
Query: 193 GFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPDYISP--EVLKSQG 250
G++HRD+ N L+ +K++DFG ++ R P P +L ++
Sbjct: 4 GYVHRDLATRNCLVGHDLVVKISDFGLARSVHSVDYYRGSEHDAIPIRWMPLEAILYNK- 180
Query: 251 GDGYYGRECDWWSVGVFLYEMLV-GDTPFYA 280
+ + D WS GV L+E+ P+Y
Sbjct: 181 ----FSTQSDVWSFGVVLWEIFAFALQPYYG 261
>32357
Length = 625
Score = 30.8 bits (68), Expect = 3.8, Method: Composition-based stats.
Identities = 13/36 (36%), Positives = 21/36 (58%), Gaps = 6/36 (16%)
Frame = -3
Query: 174 WARFYTAEVVLALDA------IHSMGFIHRDVKPDN 203
WA+ + V++ D +++ FIHRD+KPDN
Sbjct: 170 WAQIHHETVLMLADQMINRLELYTTNFIHRDLKPDN 63
>17623
Length = 687
Score = 30.8 bits (68), Expect = 3.9, Method: Compositional matrix adjust.
Identities = 16/52 (30%), Positives = 26/52 (50%), Gaps = 3/52 (5%)
Frame = +2
Query: 1290 TSARDMLLLACSQDEQKKWVTHLVKKIPKNPPSGFV---RASPRTLSTRSTA 1338
S +D L C + + TH++ +P PP G V R +P+ ST+ +A
Sbjct: 485 VSMKDPLYRPCPVSQLCNYSTHILFHLPTPPPPGHVRRHRQTPQ*TSTQHSA 640
>21210
Length = 518
Score = 29.6 bits (65), Expect = 8.1, Method: Composition-based stats.
Identities = 13/43 (30%), Positives = 21/43 (48%)
Frame = +3
Query: 236 GTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPF 278
G Y++PE + + Y D WS+G+ L E+ G P+
Sbjct: 6 GCRPYMAPERIDPRASSHGYDVRSDVWSLGITLMELATGRFPY 134
>30339
Length = 384
Score = 29.6 bits (65), Expect = 8.4, Method: Composition-based stats.
Identities = 11/27 (40%), Positives = 17/27 (62%)
Frame = -2
Query: 70 RMKAEDYEVVKVIGRGAFGEVQLVRHK 96
R D+ +KV+G+G+FG+V L K
Sbjct: 86 RFHLHDFNFIKVLGKGSFGKVMLAERK 6
>11353
Length = 454
Score = 29.6 bits (65), Expect = 9.3, Method: Composition-based stats.
Identities = 23/76 (30%), Positives = 30/76 (39%), Gaps = 3/76 (3%)
Frame = +1
Query: 1229 HEFIPTLYHFPANCDACAKPLWHVFKPPPALECRRCHVKCHRDHLDKKEDLI---CPCKV 1285
H F Y P CD C + LW K C C CH DK + L+ C
Sbjct: 142 HRFEKYTYTTPTYCDFCQQLLWGFSK--TGTHCVDCGYNCH----DKCQPLVPKTCSKLK 303
Query: 1286 SYDVTSARDMLLLACS 1301
S TSA+ +++ S
Sbjct: 304 SVSDTSAQSAVIVTRS 351
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000382697 | hsapiens_gene_ensembl | Rho-associated
protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled-
coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (Renal
carcinoma antigen NY-REN-35). [Source:Uniprot/SWISSPROT;Acc:Q13464]
(1354 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
03240 289 5e-78
30755 143 6e-34
18484 111 3e-25
27405 114 4e-25
29793 109 7e-24
31885 103 4e-22
12721 102 1e-21
00300 98 2e-20
18921 93 8e-19
14420 93 8e-19
26560 91 4e-18
09606 88 2e-17
13592 88 2e-17
00486 87 3e-17
01707 87 4e-17
15910 84 4e-16
01392 80 6e-15
26156 66 8e-15
17932 78 3e-14
05015 58 4e-14
12786 76 9e-14
13212 74 3e-13
17975 74 4e-13
01718 74 6e-13
01756 72 2e-12
13066 72 2e-12
06405 70 5e-12
01060 70 6e-12
18663 70 7e-12
19094 69 2e-11
26711 67 6e-11
21079 66 8e-11
16708 65 2e-10
14126 62 2e-09
21433 60 4e-09
04591 60 5e-09
25019 59 1e-08
03508 56 8e-08
17722 56 1e-07
29581 55 1e-07
11185 55 1e-07
19761 55 2e-07
27546 53 9e-07
00392 50 4e-06
28157 50 5e-06
00715 49 2e-05
04138 49 2e-05
01966 48 2e-05
19301 47 4e-05
37063 47 4e-05
14116 47 4e-05
37602 46 9e-05
21808 45 2e-04
07940 44 3e-04
32359 34 4e-04
07833 44 4e-04
06358 44 6e-04
32957 43 8e-04
00638 43 8e-04
14748 42 0.001
04852 42 0.001
12672 42 0.001
29590 42 0.002
11780 42 0.002
18996 40 0.005
02638 40 0.005
17300 40 0.007
07291 40 0.009
11404 39 0.013
13840 39 0.014
33586 39 0.015
18401 39 0.017
29360 39 0.021
20152 37 0.041
25829 37 0.048
18481 37 0.049
26009 37 0.079
31489 36 0.086
01106 36 0.11
17516 33 0.71
28040 33 1.0
27274 33 1.1
20640 32 1.3
32357 31 3.8
17623 31 3.9
21210 30 8.1
30339 30 8.4
11353 30 9.4
>03240
Length = 1683
Score = 289 bits (740), Expect = 5e-78, Method: Compositional matrix adjust.
Identities = 154/358 (43%), Positives = 211/358 (58%), Gaps = 46/358 (12%)
Frame = -3
Query: 64 NKIRDLRMKAED--YEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAFF 121
N IR R K + +E +K +G GAFGEV L R T +YAMK L K +++KR+ A
Sbjct: 1327 NYIRLKRAKMDKCMFEKIKTLGVGAFGEVSLCRKNDTGMLYAMKTLRKSDVLKRNQVAHV 1148
Query: 122 WEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDV-PEKWARFYTA 180
ERDI+A A++ WVV+L+Y+FQD YLY VM+Y+PGGDL+ L+ ++ E ARFY A
Sbjct: 1147 KAERDILAEADNEWVVKLYYSFQDHNYLYFVMDYVPGGDLMGLLIRMEILDEPLARFYVA 968
Query: 181 EVVLALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTCMKM---------NKEGM--- 228
E+V A++++H MGFIHRD+KPDN+L+D++GH+KL DFG C ++G
Sbjct: 967 ELVQAIESVHRMGFIHRDIKPDNILIDRNGHIKLTDFGLCTGFRWTHNSKYYQRDGTHAR 788
Query: 229 -----VRCD--------------------------TAVGTPDYISPEVLKSQGGDGYYGR 257
V+C + VGTP+YI+PEVL GG Y
Sbjct: 787 QDSMEVKCQLDEQCQCEILKPLERRRKREQRCLAHSLVGTPNYIAPEVLSRLGG---YTS 617
Query: 258 ECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLTFPDDNDISKEAKNLICAFL 317
CDWWSVGV L+EMLVG PFYA++ T K++N K+ L P ++++S+ AK+LI
Sbjct: 616 VCDWWSVGVILFEMLVGHPPFYANTPAETQYKVINWKDMLKIPRESNLSQPAKDLILRLC 437
Query: 318 TDREVRLGRNGVEEIKRHLFFKNDQWAWETLRDTVAPVVPDLSSDIDTSNFDDLEEDK 375
+ RLG NG EIK H+FF +ETLR P VP++ DTSNFD ++ DK
Sbjct: 436 CGSDDRLGLNGAGEIKTHMFFAGVN--FETLRKQQPPYVPNIRYATDTSNFDPVDPDK 269
>30755
Length = 1137
Score = 143 bits (360), Expect = 6e-34, Method: Composition-based stats.
Identities = 90/218 (41%), Positives = 122/218 (55%), Gaps = 5/218 (2%)
Frame = +2
Query: 172 EKWARFYTAEVVLALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRC 231
E+ RFY AE++ AL +HS G I+RD+K +N+LLDK GH+K+ADFG C + G
Sbjct: 29 EERTRFYGAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCKEDITYGRT-T 205
Query: 232 DTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIM 291
T GTP+Y++PEVL D YGR DWW GV +YEM+ G PFY ++ I+
Sbjct: 206 KTFCGTPEYLAPEVLD----DNDYGRAVDWWGTGVVMYEMICGRLPFYNRDHDVLFTLIL 373
Query: 292 NHKNSLTFPDDNDISKEAKNLICAFLT-DREVRL--GRNGVEEIKRHLFFKNDQWAWETL 348
+ FP +I+ EAK+L+ L D RL G++ V+EI+ H FF + W
Sbjct: 374 --VEDVKFP--RNITDEAKSLLSGLLAKDPRNRLGGGQDDVKEIQAHPFFASINWTDLVQ 541
Query: 349 RDTVAPVVPDLSSDIDTSNFDDLEEDKGE--EETFPIP 384
+ P P ++SD DT FD EE GE E T P P
Sbjct: 542 KKITPPFKPQVTSDTDTRYFD--EEFTGESVELTPPDP 649
>18484
Length = 635
Score = 111 bits (278), Expect(2) = 3e-25, Method: Composition-based stats.
Identities = 64/158 (40%), Positives = 89/158 (56%), Gaps = 4/158 (2%)
Frame = +1
Query: 172 EKWARFYTAEVVLALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMV-- 229
E A FY AE+ + L +H G I+RD+K DN++LD GH+K+ADFG C KEGM
Sbjct: 40 EPVAAFYAAEIAVGLFFLHDQGIIYRDLKLDNVMLDSEGHIKIADFGMC----KEGMTGD 207
Query: 230 -RCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYS 288
T GTPDYI+PE++ Q Y + DWW+ GV L+EML G PF + +S
Sbjct: 208 ATTRTFCGTPDYIAPEIVLYQP----YSKSVDWWAYGVLLFEMLAGQPPFDGEDEDELFS 375
Query: 289 KIMNHKNSLTFPDDNDISKEAKNLICAFLTDREV-RLG 325
I +H ++++P +S+EA +L L RLG
Sbjct: 376 SITDH--NVSYP--KAMSREAVSLCKGLLMKNPTKRLG 477
Score = 23.5 bits (49), Expect(2) = 3e-25, Method: Composition-based stats.
Identities = 12/44 (27%), Positives = 19/44 (43%)
Frame = +2
Query: 326 RNGVEEIKRHLFFKNDQWAWETLRDTVAPVVPDLSSDIDTSNFD 369
+NG +I+ H FF+ W + P P ++ NFD
Sbjct: 485 QNGERDIRDHAFFRRIVWDKIKSMEVQPPYKPKITDRRKAENFD 616
>27405
Length = 532
Score = 114 bits (284), Expect = 4e-25, Method: Composition-based stats.
Identities = 68/183 (37%), Positives = 103/183 (56%), Gaps = 6/183 (3%)
Frame = -3
Query: 86 AFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFAN----SPWVVQLFY 141
FGEV R T K+YAMK L K + + ER +++ + SP++V + Y
Sbjct: 530 GFGEVYGCRKADTGKMYAMKCLDKKRIKMKGGETLALNERIMLSLVSTGEGSPFIVCMTY 351
Query: 142 AFQDDRYLYMVMEYMPGGDLVNLMSNYDV-PEKWARFYTAEVVLALDAIHSMGFIHRDVK 200
AFQ L +++ M GGDL +S + V EK RFY AEV+L L+ +HS ++RD+K
Sbjct: 350 AFQTPEKLCFILDLMNGGDLHYHLSQHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLK 171
Query: 201 PDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPDYISPEVL-KSQGGDGYYGREC 259
P N+LLD++GH++++D G +K+ + +VGT Y++PEVL K Q Y
Sbjct: 170 PANILLDENGHVRISDLGLACDFSKK---KPHASVGTHGYMAPEVLMKGQA----YDSSA 12
Query: 260 DWW 262
DW+
Sbjct: 11 DWF 3
>29793
Length = 1088
Score = 109 bits (273), Expect = 7e-24, Method: Compositional matrix adjust.
Identities = 95/295 (32%), Positives = 154/295 (52%), Gaps = 12/295 (4%)
Frame = +2
Query: 733 RVVQIEKQCSMLDVDLKQSQQKLEHLTGNKERMEDEVKNLTLQLEQESNK-RLLLQNELK 791
R+++ EK+ S + VDL Q QQ++E + + ++ + ++ L+Q ++K
Sbjct: 176 RLLETEKKBSEMGVDLMQLQQRVERCSPSYKQRSTRAGGCPCKWSRKCKTYDNLMQGDIK 355
Query: 792 TQAFEADNLKGLEKQMKQEINTLLEAKRLLEFELAQLTKQYRGNEGQMRELQDQLEAEQY 851
T + + + K EKQ+ +EI+ L K+ + E+ +L + +E QMRE Q+QLEAE Y
Sbjct: 356 TTSMDLNKAKSKEKQLAKEISDLKHEKKTADQEIRRLKDEISVSELQMRETQEQLEAENY 535
Query: 852 FSTLYKTQVXXXXXXXXXXXXXXXXXXQELQN---EKETLATQLDLAETKAESEQLARGL 908
FS+LYKTQV ++QN EKE++ TQ+ L TKA+SE LARG+
Sbjct: 536 FSSLYKTQVKELKEEVDEKQKQIQDLTSDVQNILHEKESILTQVQLLHTKADSEALARGI 715
Query: 909 LEEQYFELTQES-------KKAASRNRQEITDKDHTVSRLEEANSMLTKDIEILRRENEE 961
EEQ ++ +E K+ SR++ E+ K+ ++ LE+ + + E L+++ ++
Sbjct: 716 AEEQLSDVEKEKTMLELEIKELMSRHKNEMNKKESQLAALEDQKRDYSINTEKLQQDKDD 895
Query: 962 LTXXXXX-XXXXXXXXXXXXISNLKAAFEKNINTERTLKTQAVNKLAEIMNRKDF 1015
L LK K + E+ K QAVNKLAEIMNRK+F
Sbjct: 896 LNNKIKRLAEDLQSSKNMSEFDKLK----KQLEDEKLKKIQAVNKLAEIMNRKEF 1048
>31885
Length = 529
Score = 103 bits (258), Expect = 4e-22, Method: Compositional matrix adjust.
Identities = 58/162 (35%), Positives = 91/162 (56%), Gaps = 5/162 (3%)
Frame = -2
Query: 126 DIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDL-VNLMSNYDVPEKWARFYTAEVVL 184
D++ + P++V L+YAFQD+ L+MV++ GGDL ++ E +FY ++ L
Sbjct: 516 DMLTRLDHPFLVNLWYAFQDEEDLFMVVDLFLGGDLRYHMQQEVSFREDCVKFYLCQLAL 337
Query: 185 ALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPDYISPE 244
LD + S +HRD+KPDN+LLD+ GH + DF ++ + + + GT Y++PE
Sbjct: 336 VLDYLRSQKIVHRDIKPDNILLDEQGHCHVTDFNIATQLEDDELAT--STSGTRPYMAPE 163
Query: 245 V----LKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADS 282
V + + G YG DWWS+GV L+E+L PF S
Sbjct: 162 VYGVAINERRG---YGFPVDWWSLGVSLFELLKKRRPFSVHS 46
>12721
Length = 821
Score = 102 bits (253), Expect = 1e-21, Method: Composition-based stats.
Identities = 60/198 (30%), Positives = 109/198 (55%)
Frame = +1
Query: 82 IGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFY 141
IG G+ G V + + R++ + K ++ K+ + E +M + P +V+++
Sbjct: 112 IGEGSTGIVCIATSRDGRQM----AVKKMDLRKQQRRELLFNEVVVMRDYHHPNIVEMYN 279
Query: 142 AFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKWARFYTAEVVLALDAIHSMGFIHRDVKP 201
++ + L++VME+M GG L ++++N + E + AL +H+ G IHRD+K
Sbjct: 280 SYLVNDELWVVMEFMEGGALTDIVTNNRMDEVQIATVCRACLKALAFLHANGVIHRDIKS 459
Query: 202 DNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPDYISPEVLKSQGGDGYYGRECDW 261
D++LL G +KL DFG C ++ ++ R + VGTP +++PEV+ YG E D
Sbjct: 460 DSILLSHDGKVKLXDFGFCAQVTQDLQKR-KSLVGTPYWMAPEVISRLP----YGPEVDI 624
Query: 262 WSVGVFLYEMLVGDTPFY 279
WS+G+ + EM+ + PF+
Sbjct: 625 WSLGIMVMEMIDAEPPFF 678
>00300
Length = 2318
Score = 98.2 bits (243), Expect = 2e-20, Method: Compositional matrix adjust.
Identities = 64/200 (32%), Positives = 99/200 (49%), Gaps = 2/200 (1%)
Frame = -1
Query: 82 IGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFY 141
IG G FG+V + ST ++ A+K + KF+ +E I +V+ +
Sbjct: 1634 IGEGQFGKVYTAVNMSTGELMALKEM-KFQPNDLQQLREMCDEIKIFEGIQHENLVKYYG 1458
Query: 142 AFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKWARFYTAEVVLALDAIHSMGFIHRDVKP 201
+ M MEY G + + +PE R YT E+VLA++ +H +HRD+K
Sbjct: 1457 VEVHKDEMLMFMEYCDTGT-IEEAAKMGLPEYLIRRYTREIVLAVNHLHENSIVHRDIKG 1281
Query: 202 DNMLLDKSGHLKLADFGTCMKMNKEGMVRCD--TAVGTPDYISPEVLKSQGGDGYYGREC 259
N+ L +GH+KL DFG +K+ + + VGT Y++PEV +Q G YGR
Sbjct: 1280 ANIFLTSNGHVKLGDFGCSVKLKSHTTMPGEFHNLVGTTAYMAPEVF-TQNDQGGYGRAA 1104
Query: 260 DWWSVGVFLYEMLVGDTPFY 279
D WS+G + EM G P++
Sbjct: 1103 DIWSLGCVVIEMATGKRPWH 1044
>18921
Length = 697
Score = 92.8 bits (229), Expect = 8e-19, Method: Compositional matrix adjust.
Identities = 63/211 (29%), Positives = 111/211 (52%), Gaps = 2/211 (0%)
Frame = +2
Query: 76 YEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSPW 135
++++ +G G++G V HK T +V A+K ++ +D +E IM +S +
Sbjct: 35 FDILGKLGEGSYGSVFKSLHKETGQVLAIK-----QVPVDTDLQEIIKEISIMQQCDSKY 199
Query: 136 VVQLFYAFQDDRYLYMVMEYMPGGDLVNLMS--NYDVPEKWARFYTAEVVLALDAIHSMG 193
+V+ + ++ + L++VMEY G + ++M N + E+ + L +HS
Sbjct: 200 IVKYYGSYFKNTDLWIVMEYCGAGSVSDIMRLRNKTLVEREIATILYYTLKGLXYLHSRR 379
Query: 194 FIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPDYISPEVLKSQGGDG 253
IHRD+K N+LL+ GH KLADFG ++ + M + +T +GTP +++PEV++ G
Sbjct: 380 KIHRDIKAGNILLNNEGHAKLADFGVAGQLT-DTMAKRNTVIGTPYWMAPEVIQEIG--- 547
Query: 254 YYGRECDWWSVGVFLYEMLVGDTPFYADSLV 284
Y D WS+G+ EM G P S++
Sbjct: 548 -YDCVADIWSLGITALEMAEGKPPVMETSIL 637
>14420
Length = 528
Score = 92.8 bits (229), Expect = 8e-19, Method: Compositional matrix adjust.
Identities = 51/146 (34%), Positives = 82/146 (56%)
Frame = +2
Query: 133 SPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKWARFYTAEVVLALDAIHSM 192
+P +V ++ L++VME++ GG L ++++ + E E + AL+ +H
Sbjct: 77 NPNIVNYLDSYLVGEELWVVMEFLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHEN 256
Query: 193 GFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPDYISPEVLKSQGGD 252
IHRD+K DN+LL G +KL DFG C +++ E R T VGTP +++PEV+ +
Sbjct: 257 QVIHRDIKSDNILLGMDGSVKLTDFGFCAQLSPEQSKR-STMVGTPYWMAPEVVTRK--- 424
Query: 253 GYYGRECDWWSVGVFLYEMLVGDTPF 278
YG D WS+GV EM+ G+ P+
Sbjct: 425 -QYGPTVDIWSLGVMCIEMIEGEPPY 499
>26560
Length = 398
Score = 90.5 bits (223), Expect = 4e-18, Method: Composition-based stats.
Identities = 47/108 (43%), Positives = 69/108 (63%), Gaps = 1/108 (0%)
Frame = -1
Query: 172 EKWARFYTAEVVLALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRC 231
EK RFY AEV+L L+ +HS ++RD+KP N+LLD++GH++++D G +K+ R
Sbjct: 359 EKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGLACDFSKK---RP 189
Query: 232 DTAVGTPDYISPEVL-KSQGGDGYYGRECDWWSVGVFLYEMLVGDTPF 278
+VGT Y++PEVL K Q Y DW+S G LY++L G +PF
Sbjct: 188 HASVGTHGYMAPEVLMKGQS----YDSSADWFSFGCMLYKLLKGHSPF 57
>09606
Length = 1300
Score = 88.2 bits (217), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 66/246 (26%), Positives = 115/246 (46%), Gaps = 22/246 (8%)
Frame = -3
Query: 69 LRMKAEDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAFFWEERDIM 128
L + E++ + + +G+G + R K T A+ + K + + +++ DI
Sbjct: 1130 LITRMENFVLYEELGKGEHSIIYKGRRKGTINFVAIHCIEKCKRPEVTNTVRM--THDI- 960
Query: 129 AFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMS-NYDVPEKWARFYTAEVVLALD 187
+ P VVQ ++ +L++V+E GG L ++++ ++ +PE R + +V L
Sbjct: 959 ---SHPNVVQFHEWYETSNHLWLVVELCTGGSLADILAQDHHLPETSIRDFGIHLVTGLH 789
Query: 188 AIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTC-----------MKMNKEG--------- 227
IHS+G + D++P +LLD SG LK ADFG K + G
Sbjct: 788 YIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQWNIQSAE 609
Query: 228 -MVRCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGT 286
M++ G+P Y++PEV QG + D W++G YEM G PF ++ T
Sbjct: 608 EMMKQVPTSGSPTYMAPEVF--QGAEP--SIMSDLWALGCVFYEMFSGHPPFLGETYDIT 441
Query: 287 YSKIMN 292
K++N
Sbjct: 440 KDKVLN 423
>13592
Length = 980
Score = 87.8 bits (216), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 66/205 (32%), Positives = 106/205 (51%), Gaps = 8/205 (3%)
Frame = +2
Query: 82 IGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAFF---WEERDIMAFANSPWVVQ 138
IG+G FG+V + +T ++ AMK ++ I+ ++ EE I+ +V+
Sbjct: 8 IGQGRFGKVYTAVNNNTGELMAMKEIA----IQPGETRALKNVAEELKILEGIKHKNLVR 175
Query: 139 LFYAFQDDRY-LYMVMEYMPGGDLVNLMS-NYDVPEKWARFYTAEVVLALDAIHSMGFIH 196
+Y + R L + ME G L +L+ +PE +R +TA+++ + +H G +H
Sbjct: 176 -YYGIEVHREELLIFMELCSEGTLESLVELTGGLPEALSRRFTAQLLSGVAELHKHGIVH 352
Query: 197 RDVKPDNM-LLDKSGHLKLADFGTCMKMNKEGMVRCD--TAVGTPDYISPEVLKSQGGDG 253
RD+K N+ L+D S LKL DFG+ +K+ V + VGT Y++PEV DG
Sbjct: 353 RDIKTANIFLVDGSNSLKLGDFGSAVKIQAHTTVPGELQGYVGTQAYMAPEVFTKTNSDG 532
Query: 254 YYGRECDWWSVGVFLYEMLVGDTPF 278
+GR D WSVG + EM G P+
Sbjct: 533 -HGRLADIWSVGCVVVEMASGKRPW 604
>00486
Length = 797
Score = 87.4 bits (215), Expect = 3e-17, Method: Composition-based stats.
Identities = 54/140 (38%), Positives = 74/140 (52%), Gaps = 3/140 (2%)
Frame = -2
Query: 233 TAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMN 292
T GT +Y++PE+L G +G+ DWWS+G +Y+ML G PF A++ T KI+
Sbjct: 781 TFCGTIEYMAPEILTRTG----HGKAVDWWSLGALMYDMLTGSPPFTAENRKKTIDKIL- 617
Query: 293 HKNSLTFPDDNDISKEAKNLICAFLTDREV-RL--GRNGVEEIKRHLFFKNDQWAWETLR 349
K L P ++ EA+ LI L RL G + IK H FF+N WA LR
Sbjct: 616 -KGKLNLPP--YLTNEARGLIKKLLRKNPAERLGGGHDDSGPIKDHQFFRNTNWALLALR 446
Query: 350 DTVAPVVPDLSSDIDTSNFD 369
P P+++SD DTS FD
Sbjct: 445 RAEPPFRPNVTSDEDTSQFD 386
>01707
Length = 757
Score = 87.0 bits (214), Expect = 4e-17, Method: Compositional matrix adjust.
Identities = 65/208 (31%), Positives = 105/208 (50%), Gaps = 5/208 (2%)
Frame = +1
Query: 72 KAEDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFE---MIKRSDSAFFWEERDIM 128
+ E YE + IG G++G V R+K T ++ A+K + E +IK+ E ++
Sbjct: 58 RMEKYEKIGKIGEGSYGVVFKCRNKETSQLVAIKKFVESEDDPLIKKIAM----REIRML 225
Query: 129 AFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNY--DVPEKWARFYTAEVVLAL 186
P +V+L F+ + L++V +Y+ L+N + Y +PE + + +LA+
Sbjct: 226 KQLKHPNLVRLIEVFRRKKRLHLVFDYV-DHTLLNELDRYPRGLPEPMVKRIIYQTLLAV 402
Query: 187 DAIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPDYISPEVL 246
+ H IHRDVKP+N+L+ + G +KL DFG + G D V T Y +PE+L
Sbjct: 403 NFCHQYNTIHRDVKPENILITRQGQVKLCDFGFARILTGPGDEYTD-YVATRWYRAPELL 579
Query: 247 KSQGGDGYYGRECDWWSVGVFLYEMLVG 274
GD YG D W++G E+L G
Sbjct: 580 V---GDTQYGPPVDVWAIGCVFAELLTG 654
>15910
Length = 1361
Score = 84.0 bits (206), Expect = 4e-16, Method: Compositional matrix adjust.
Identities = 53/139 (38%), Positives = 80/139 (57%), Gaps = 5/139 (3%)
Frame = +2
Query: 180 AEVVLALDAIHSMGFIHRDVKPDNML---LDKSGHLKLADFGTCMKMNKEGMVRCDTAVG 236
++++ + IH+ G +HRD+KP+N+L + LKLADFG + E V+ T G
Sbjct: 485 SDILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLADFGLSRIIEPE--VQMSTVCG 658
Query: 237 TPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNS 296
TP Y +PEVLK GD Y D WSVGV Y +L G PF+A++ Y KI+ K
Sbjct: 659 TPGYCAPEVLK---GDKY-TPSVDMWSVGVIAYILLCGYEPFFAENEFEMYRKII--KGE 820
Query: 297 LTFPDD--NDISKEAKNLI 313
F ++ ++IS+ AK+++
Sbjct: 821 YKFDEEYWSEISENAKDVV 877
>01392
Length = 1806
Score = 80.1 bits (196), Expect = 6e-15, Method: Composition-based stats.
Identities = 44/117 (37%), Positives = 65/117 (55%), Gaps = 8/117 (6%)
Frame = -1
Query: 172 EKWARFYTAEVVLALDAIHSMGFIHRDVKPDNML---LDKSGHLKLADFGTCMKMNKEG- 227
E+ A + ALD +HS G HRD+KP+N+L LD +K+ DF ++ +G
Sbjct: 1794 EREASLVVRHIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGISCDGD 1615
Query: 228 ---MVRCDTAVGTPDYISPEVLKSQGGDGY-YGRECDWWSVGVFLYEMLVGDTPFYA 280
T VG+ +Y++PEV+ + GD + Y + CD WS+G+ LY ML G PFY
Sbjct: 1614 GTKTPELLTPVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILYIMLCGYPPFYG 1444
>26156
Length = 479
Score = 66.2 bits (160), Expect(2) = 8e-15, Method: Compositional matrix adjust.
Identities = 38/112 (33%), Positives = 68/112 (60%), Gaps = 4/112 (3%)
Frame = -1
Query: 70 RMKAEDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAFFWEERDIMA 129
++ D+ +++VIGRG++ +V V HK T+++YAMK++ K E++ D W + +
Sbjct: 401 KLGLTDFLLLRVIGRGSYAKVLQVEHKRTKRIYAMKVIKK-ELVN-DDEDIDWVQTEKHV 228
Query: 130 F---ANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLV-NLMSNYDVPEKWARF 177
F N P++V L FQ + L+ V+E++ GGDL+ ++ +PE+ ARF
Sbjct: 227 FETATNYPFLVGLHSCFQSESRLFFVIEFVNGGDLMFHMQRQRRLPEEHARF 72
Score = 33.5 bits (75), Expect(2) = 8e-15, Method: Composition-based stats.
Identities = 12/24 (50%), Positives = 19/24 (79%)
Frame = -3
Query: 177 FYTAEVVLALDAIHSMGFIHRDVK 200
FY+AE+ LAL+ +H G ++RD+K
Sbjct: 75 FYSAEICLALNFLHKRGIVYRDLK 4
>17932
Length = 597
Score = 77.8 bits (190), Expect = 3e-14, Method: Composition-based stats.
Identities = 44/110 (40%), Positives = 67/110 (60%), Gaps = 4/110 (3%)
Frame = -3
Query: 300 PDDNDISKEAKNLICAFLTDREVRLGRNGVEEIKRHLFFKNDQWAWETLRDTVAPVVPDL 359
P + +SKEA++LI L+D + RLG E+++H FFK WA +R+ + P VP +
Sbjct: 475 PPHSSVSKEARDLISQLLSDGKSRLGW---PELQQHPFFKTVDWA--NIRNAMPPYVPSI 311
Query: 360 SSDIDTSNFDDLEEDKGEE--ETF--PIPKAFVGNQLPFVGFTYYSNRRY 405
SS DTS+FD++E+ + ++F P + F G LPFVGFTY+ R+
Sbjct: 310 SSLDDTSHFDEVEKARPAPNIDSFHQPSSRDFTGRHLPFVGFTYFHPPRH 161
Score = 52.0 bits (123), Expect = 2e-06, Method: Composition-based stats.
Identities = 24/51 (47%), Positives = 32/51 (62%), Gaps = 2/51 (3%)
Frame = -2
Query: 261 WWSVGVFLYEMLVGDTPFYAD--SLVGTYSKIMNHKNSLTFPDDNDISKEA 309
WWS+GV YEML G TPF D S+V TY+ IMN+K + + P + + A
Sbjct: 596 WWSLGVCAYEMLFGCTPFTDDDGSMVATYNNIMNYKTNSSSPSQQRVQRGA 444
>05015
Length = 894
Score = 58.2 bits (139), Expect(2) = 4e-14, Method: Compositional matrix adjust.
Identities = 38/88 (43%), Positives = 54/88 (61%), Gaps = 1/88 (1%)
Frame = +3
Query: 1038 QLELNQEREKFNQMVVKHQKELNDMQAQLVEECAHRNELQMQLASKESDIEQLRAKL-LD 1096
Q EL EREK+N+MV K Q+++ + Q + EE R LQM++ +K+S+IEQLR KL L
Sbjct: 621 QQELTMEREKYNKMVEKMQRDVAEAQQNVYEESLSRQRLQMEMDAKDSEIEQLRLKLSLF 800
Query: 1097 LSDSTSVASFPSADETDGNLPESRIEGW 1124
+D TS S S +E+ + E GW
Sbjct: 801 NADVTSTHSTGSLEES---VVEESTSGW 875
Score = 39.3 bits (90), Expect(2) = 4e-14, Method: Compositional matrix adjust.
Identities = 23/45 (51%), Positives = 31/45 (68%), Gaps = 2/45 (4%)
Frame = +2
Query: 1000 TQAVNKLAEIMNRKDFK--IDRKKANTQDLRKKEKENRKLQLELN 1042
+QAVNKLAEIMNRK+F+ + KA DL++KEK+ R+ N
Sbjct: 500 SQAVNKLAEIMNRKEFRRGGGKDKAVGSDLKRKEKDLRRGSTRTN 634
>12786
Length = 460
Score = 75.9 bits (185), Expect = 9e-14, Method: Compositional matrix adjust.
Identities = 46/121 (38%), Positives = 68/121 (56%), Gaps = 18/121 (14%)
Frame = -3
Query: 176 RFYTAEVVLALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTC--MKMNKEGMVRCDT 233
+FY E++ A+ A+H+ G IH D+KP N +L +G+LKL DFG ++ +K +++ D+
Sbjct: 401 KFYWREMLRAVKALHNEGVIHSDLKPANFML-VAGNLKLIDFGIANTLQQDKTSVLK-DS 228
Query: 234 AVGTPDYISPEVLK---------SQGGDGY-------YGRECDWWSVGVFLYEMLVGDTP 277
VGTP Y+SPE + S DG+ G D WS+G LY M+ G TP
Sbjct: 227 RVGTPSYMSPEAIMAACDDSADDSMEEDGHRTKPKYKVGVRSDVWSLGCILYNMVYGRTP 48
Query: 278 F 278
F
Sbjct: 47 F 45
>13212
Length = 1067
Score = 74.3 bits (181), Expect = 3e-13, Method: Compositional matrix adjust.
Identities = 44/116 (37%), Positives = 66/116 (56%), Gaps = 3/116 (2%)
Frame = -1
Query: 159 GDLVNLMSNYDVPEKWAR--FYTAEVVLALDAIHSMGFIHRDVKPDNMLLDKSGHLKLAD 216
G L ++M + + P A+ + E+ +ALD +H IHRD+K N+LL G +KLAD
Sbjct: 1028 GALDSIMVDLEKPMTEAQICYVCHEMCMALDFLHRHHVIHRDIKAGNVLLTIDGEVKLAD 849
Query: 217 FGTCMKMNKEGMVRCDTAVGTPDYISPEVLKSQG-GDGYYGRECDWWSVGVFLYEM 271
FG K N + + DT +GTP +++PEV+ + D Y + D WS+GV L E
Sbjct: 848 FGVSAK-NTQTQQKRDTFIGTPYWMAPEVVLCETLKDTPYDFKADIWSLGVTLIEF 684
>17975
Length = 449
Score = 73.9 bits (180), Expect = 4e-13, Method: Composition-based stats.
Identities = 48/144 (33%), Positives = 79/144 (54%), Gaps = 5/144 (3%)
Frame = +3
Query: 87 FGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFYAFQDD 146
F V+L RH T + A+K++ K ++ + S S F E R M P VV+L+
Sbjct: 6 FAVVKLARHVFTGEKVAVKVIDKTKLDEVSRSHLFQEVR-CMKLVQHPNVVRLYEVIDTQ 182
Query: 147 RYLYMVMEYMPGGDLVNLMSNYD--VPEKWARFYTAEVVLALDAIHSMGFIHRDVKPDNM 204
LY+++E GGD+ + + + + EK A+ Y ++V A+ H + +HRD+KP+N+
Sbjct: 183 TKLYLILELGDGGDMYDYIMRHSGGLEEKLAKRYFRQIVEAISYCHKLHVVHRDLKPENV 362
Query: 205 L-LDKSGHLKLADFG--TCMKMNK 225
+ +K G +KL DFG TC+ K
Sbjct: 363 VFFEKPGLVKLTDFGFSTCLLQAK 434
>01718
Length = 959
Score = 73.6 bits (179), Expect = 6e-13, Method: Compositional matrix adjust.
Identities = 59/200 (29%), Positives = 95/200 (47%), Gaps = 10/200 (5%)
Frame = +3
Query: 82 IGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFY 141
IG G F EV V H+ T +V A+K+ + S+ E ++ +++
Sbjct: 171 IGAGFFSEVFKVTHRITGQVMALKMNTM-----TSNRHNMLREVQLLNRLQHANILRFMG 335
Query: 142 AFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKWARFYTAEVVLA--LDAIHSMGFIHRDV 199
+ L+ + EY+P G+L L+ D W + + LA LD +HS FIHRD+
Sbjct: 336 VCVHEGQLHALTEYIPSGNLEQLLEKKDEELPWTQRIQLTLGLARGLDYLHSTRFIHRDL 515
Query: 200 KPDNMLL---DKSG-HLKLADFGTCMK----MNKEGMVRCDTAVGTPDYISPEVLKSQGG 251
N+L+ D G H +ADFG K ++KE + VG+P +++PEVL
Sbjct: 516 TSKNILIRREDNHGYHAVIADFGLATKIPDPLDKEKL----PTVGSPYWMAPEVLNGH-- 677
Query: 252 DGYYGRECDWWSVGVFLYEM 271
+Y D +SVG+ + E+
Sbjct: 678 --FYNERADLFSVGIIMCEI 731
>01756
Length = 1858
Score = 71.6 bits (174), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 72/211 (34%), Positives = 97/211 (45%), Gaps = 15/211 (7%)
Frame = -3
Query: 76 YEVVKVIGRGAFGEVQLVRHKSTRKVYAMK-LLSKFEMIKRSDSAFFWEERDIMAFANSP 134
YE + IG+G FGEV R K T++V AMK +L E +A E I+ N
Sbjct: 1736 YEKLAKIGQGTFGEVFKARCKKTKQVVAMKKVLMDNEKEGFPITAL--REIKILQLLNHE 1563
Query: 135 WVVQLF-----YAFQDDRY---LYMVMEYMPGGDLVNLMSN----YDVPEKWARFYTAEV 182
VV L A +RY Y+V E+ DL L+SN +++PE + ++
Sbjct: 1562 NVVDLIEICSTKATSANRYKSMFYLVFEFCEH-DLAGLLSNMSVVFNLPE--IKEVMKQL 1392
Query: 183 VLALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFGT--CMKMNKEGMVRCDTAVGTPDY 240
+ L IH +HRD+K N+L+ K G LKLADFG +N R V T Y
Sbjct: 1391 MNGLYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWY 1212
Query: 241 ISPEVLKSQGGDGYYGRECDWWSVGVFLYEM 271
PE+L GD Y D W G + EM
Sbjct: 1211 RPPELLL---GDRNYSTAIDQWGAGCIMAEM 1128
>13066
Length = 551
Score = 71.6 bits (174), Expect = 2e-12, Method: Composition-based stats.
Identities = 47/151 (31%), Positives = 78/151 (51%), Gaps = 5/151 (3%)
Frame = +3
Query: 120 FFWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYD-VPEKWARFY 178
FF E D++ + P+++Q+ Q ++ M + GDL+ + V EK A+ +
Sbjct: 114 FFPRELDLLTKLDHPYIIQIHSILQRXPKNFIFMRFAERGDLLTYIQEVGFVKEKQAKIW 293
Query: 179 TAEVVLALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFG-TCMKMNKEG---MVRCDTA 234
++ AL+ +HS HRD+K +N+LL ++KLADFG C + + G M R T
Sbjct: 294 FYQMTTALNYLHSYDVAHRDLKCENILLSSHFNVKLADFGFACACITESGEKYMSR--TY 467
Query: 235 VGTPDYISPEVLKSQGGDGYYGRECDWWSVG 265
G+ Y +PE++ G Y + D WS+G
Sbjct: 468 CGSAAYAAPEIVY---GAPYAPKVADAWSLG 551
>06405
Length = 1965
Score = 70.5 bits (171), Expect = 5e-12, Method: Compositional matrix adjust.
Identities = 71/259 (27%), Positives = 112/259 (43%), Gaps = 6/259 (2%)
Frame = +1
Query: 35 DALVYDLDFPALRKNKNIDNFLSRYKDTINKIRDLRMKAEDYEVV--KVIGRGAFGEVQL 92
D LV L +PA ++ K +S D R + E E+ +G G +G+V
Sbjct: 160 DGLVTTLLYPAPKRQKPTVFGVSPEPD--------RWEIERTEIAMKHRLGGGQYGDVYE 315
Query: 93 VRHKSTRKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFYAFQDDRYLYMV 152
K K+ A+K L K + + +D F EE IM P +VQL + Y+V
Sbjct: 316 AMWKRYNKIVAVKTL-KEDTMALND---FLEEAAIMKEMKHPNLVQLLGVCTREPPFYIV 483
Query: 153 MEYMPGGDLVNLMSNYDVPEKW--ARFYTA-EVVLALDAIHSMGFIHRDVKPDNMLLDKS 209
E+MP G+L++ + + E A Y A ++ + + + FIHRD+ N L+ S
Sbjct: 484 TEFMPHGNLLDYLRSSTREENGPTALMYMATQIASGMAYLETKNFIHRDLAARNCLVADS 663
Query: 210 GHLKLADFGTCMKMNKEGMVRCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLY 269
+K+ADFG M + A + +PE L + D W+ GV L+
Sbjct: 664 NMVKVADFGLARLMKDDTYTAHIGAKFPIKWTAPEGLAFN----RFSTRSDIWAFGVLLW 831
Query: 270 EMLV-GDTPFYADSLVGTY 287
E+ G +P+ L Y
Sbjct: 832 ELATYGMSPYPGVELTEVY 888
>01060
Length = 1800
Score = 70.1 bits (170), Expect = 6e-12, Method: Compositional matrix adjust.
Identities = 64/219 (29%), Positives = 97/219 (44%), Gaps = 9/219 (4%)
Frame = +1
Query: 82 IGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAFFWEERDIMAF--ANSPWVVQL 139
IG G +G V RH++T + AMK K + D R+I +V L
Sbjct: 97 IGEGTYGVVYKCRHRATGRKLAMK---KIRLRGSEDGVPSSAIREIAMLRELRHTNIVCL 267
Query: 140 FYAFQDDRYLYMVMEYMPGGDLVNLMSNYDVPE------KWARFYTAEVVLALDAIHSMG 193
+D L++V E++ DL + + PE + + Y ++V + H
Sbjct: 268 EDVIMEDERLFLVFEFL-SMDLKMYIDKF--PEGVVLDRRLVKSYVFQIVTGIXFCHQRR 438
Query: 194 FIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTA-VGTPDYISPEVLKSQGGD 252
+HRD+KP N+L++ +G +K+ADFG M VR T V T Y +PE+L G
Sbjct: 439 IVHRDLKPQNLLINHTGAIKIADFG--MARTFALPVRAYTHEVVTLWYRAPEILM---GA 603
Query: 253 GYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIM 291
Y D WS+G +ML+ F DS + KI
Sbjct: 604 SKYSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIF 720
>18663
Length = 600
Score = 69.7 bits (169), Expect = 7e-12, Method: Composition-based stats.
Identities = 49/147 (33%), Positives = 70/147 (47%), Gaps = 11/147 (7%)
Frame = +2
Query: 233 TAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMN 292
T GTP+YI+PE+L+ + YG DWW++GV LYEML G +PF D + + N
Sbjct: 5 TFCGTPNYIAPEILRGED----YGFSVDWWALGVLLYEMLAGRSPF--DIAGASENPDQN 166
Query: 293 HKNSL-------TFPDDNDISKEAKNLICAFLTDREV-RLG---RNGVEEIKRHLFFKND 341
++ L T +S +A +++ FL RLG + +I H FFK
Sbjct: 167 TEDYLFQVILEKTIRIPRSLSVKAASVLKGFLNKNPADRLGCHRESAFMDIVNHPFFKVI 346
Query: 342 QWAWETLRDTVAPVVPDLSSDIDTSNF 368
W + P P L SD D +NF
Sbjct: 347 DWEMLERKQVSPPFKPRLDSDRDLANF 427
>19094
Length = 898
Score = 68.6 bits (166), Expect = 2e-11, Method: Composition-based stats.
Identities = 35/87 (40%), Positives = 53/87 (60%)
Frame = +1
Query: 189 IHSMGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPDYISPEVLKS 248
+HS IHRD+K N+LL+ GH KLADFG ++ + M + +T +GTP +++PEV++
Sbjct: 106 LHSRRKIHRDIKAGNILLNNEGHAKLADFGVAGQLT-DTMAKRNTVIGTPYWMAPEVIQE 282
Query: 249 QGGDGYYGRECDWWSVGVFLYEMLVGD 275
G Y D WS+G+ EM G+
Sbjct: 283 IG----YDCVADIWSLGITALEMAEGN 351
>26711
Length = 405
Score = 66.6 bits (161), Expect = 6e-11, Method: Composition-based stats.
Identities = 45/136 (33%), Positives = 67/136 (49%), Gaps = 3/136 (2%)
Frame = -2
Query: 181 EVVLALDAIHSMGFIHRDVKPDNMLL--DKSGHLKLADFGTCMKMNKEGMVRCDTAVGTP 238
+V+ L +H+ G +H D+KP N+LL DK ++L DFG K+ + GTP
Sbjct: 392 QVLDILQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARKLYPPQETFLNH--GTP 219
Query: 239 DYISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLT 298
+ SPE L + D W VGV Y +L G +PF ADS + K S
Sbjct: 218 GFTSPEALDVKP----ISTASDVWGVGVLAYILLSGQSPFQADSATESLKKTQTCDWSFD 51
Query: 299 F-PDDNDISKEAKNLI 313
P +++S++AK+ I
Sbjct: 50 VCPSFSNMSQDAKDFI 3
>21079
Length = 878
Score = 66.2 bits (160), Expect = 8e-11, Method: Composition-based stats.
Identities = 42/148 (28%), Positives = 76/148 (51%), Gaps = 4/148 (2%)
Frame = +1
Query: 134 PWVVQLFYAFQDDRYLYMVMEYMPGGDLVN--LMSNYDVPEKWARFYTAEVVLALDAIHS 191
P ++ L+ AF+ R + +VME++ G+L + ++ + E+ + ++ + +H+
Sbjct: 4 PKLLMLWDAFEAPRTMVLVMEFVGAGELFERVIRDDFVLTERDCVHFVRQICSGVGYMHT 183
Query: 192 MGFIHRDVKPDNMLL--DKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPDYISPEVLKSQ 249
+H D+KP+N+L D S +K+ DFG + K G GTP++I+PEV+
Sbjct: 184 QSILHLDLKPENVLCVSDNSNQIKIIDFGLA-RFYKPGD-SLQVLFGTPEFIAPEVVNYD 357
Query: 250 GGDGYYGRECDWWSVGVFLYEMLVGDTP 277
D WS+GV Y +L G +P
Sbjct: 358 ----EINFTTDMWSIGVICYILLSGLSP 429
>16708
Length = 1397
Score = 65.1 bits (157), Expect = 2e-10, Method: Composition-based stats.
Identities = 44/156 (28%), Positives = 78/156 (50%), Gaps = 15/156 (9%)
Frame = -1
Query: 78 VVKVIGRGAFGEVQLVRHKSTRKVYAMKL-------LSKFEMIKRSDSAFFWEERDIMAF 130
+++V+G+G FG+V R ST + A+K L + E + R + F+ +A
Sbjct: 1391 ILQVLGKGVFGKVYEARLLSTHEKAALKTSILCHHSLDEVEALGRIEGGFY------LAQ 1230
Query: 131 ANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNY---DVPEKWAR-----FYTAEV 182
WV L + + +++ + G L N+ ++Y ++P +W+ +
Sbjct: 1229 MFGAWVTCLPFP-----KMNILLHFYEMGPLCNVYAHYKNKEMPIRWSNPAMVCCIAGQX 1065
Query: 183 VLALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFG 218
V AL+ IH +G +H DVK DN+L+D G+ KL D+G
Sbjct: 1064 VCALEHIHELGVVHMDVKADNVLVDAHGNCKLTDYG 957
>14126
Length = 1265
Score = 61.6 bits (148), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 66/221 (29%), Positives = 93/221 (42%), Gaps = 14/221 (6%)
Frame = +3
Query: 76 YEVVKVIGRGAFGEVQLVRH-KSTRKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFAN-- 132
YE V VIG GA+G V R ++ + AMK + + + R+I
Sbjct: 195 YEEVAVIGNGAYGTVYKARDLRNQGEFVAMK---RIRLNNTEEGMPMMAIREISMLKQLE 365
Query: 133 ---SPWVVQLFYAFQD---DR--YLYMVMEYMPGGDLVNLMSNYDVPEKWA---RFYTAE 181
P VV+L + DR L +V EY+ DL ++ P + +
Sbjct: 366 QYEHPNVVRLLDVSHNTITDREIRLNLVFEYIEH-DLATYLAKCPSPGLGPDRIKDLMLQ 542
Query: 182 VVLALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPDYI 241
++ +D +HS +HRD+KP N+L+ K G LKLADFG + + T V T Y
Sbjct: 543 LLNGVDFLHSNRIVHRDLKPQNLLISKDGRLKLADFGLARIYSFH--MALTTVVVTLWYR 716
Query: 242 SPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADS 282
SPEVL YG D WS G E+ F S
Sbjct: 717 SPEVLMQ----AEYGTSVDIWSCGCIFAELFTRRALFKGSS 827
>21433
Length = 590
Score = 60.5 bits (145), Expect = 4e-09, Method: Composition-based stats.
Identities = 40/101 (39%), Positives = 54/101 (53%)
Frame = +2
Query: 178 YTAEVVLALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGT 237
Y ++ AL+ H IHRD+KP+N+LL G LK+ADFG + R T GT
Sbjct: 182 YIYQLSSALEYCHYRKVIHRDIKPENLLLGLKGDLKIADFGWSVHAPSS---RRTTMCGT 352
Query: 238 PDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPF 278
DY+ PE+++ + D D WS+GV YE LVG P
Sbjct: 353 LDYLPPEMVEGKTHD----ENVDLWSLGVLCYEFLVGTPPL 463
>04591
Length = 1117
Score = 60.5 bits (145), Expect = 5e-09, Method: Compositional matrix adjust.
Identities = 45/125 (36%), Positives = 62/125 (49%), Gaps = 2/125 (1%)
Frame = -2
Query: 149 LYMVMEYMPGGDLVNLMSNYDVPEKWA--RFYTAEVVLALDAIHSMGFIHRDVKPDNMLL 206
Y++ EY DL L++N V A + ++++ L IH+ +HRD+K N+LL
Sbjct: 972 FYLIFEYC-DYDLAGLLNNLRVKFSLADKKNLMSQLLNGLFYIHTKQILHRDIKAANILL 796
Query: 207 DKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGV 266
+ G LKLADFG K R V T Y PE+L G+ YG E D W VG
Sbjct: 795 TRDGVLKLADFGLSRPWVKSK--RLTNRVVTLWYRPPELLL---GEREYGPEIDMWGVGC 631
Query: 267 FLYEM 271
+ EM
Sbjct: 630 IMAEM 616
>25019
Length = 730
Score = 58.9 bits (141), Expect = 1e-08, Method: Composition-based stats.
Identities = 29/64 (45%), Positives = 39/64 (60%)
Frame = +3
Query: 202 DNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPDYISPEVLKSQGGDGYYGRECDW 261
+N+LLDK GH+KL DFG C K G T GT +Y++PE+L G +G+ DW
Sbjct: 261 ENVLLDKDGHVKLTDFGLC-KEAITGTRVTHTFCGTIEYMAPEILTRTG----HGKAVDW 425
Query: 262 WSVG 265
WS+G
Sbjct: 426 WSLG 437
>03508
Length = 1463
Score = 56.2 bits (134), Expect = 8e-08, Method: Compositional matrix adjust.
Identities = 39/118 (33%), Positives = 59/118 (50%), Gaps = 1/118 (0%)
Frame = +1
Query: 161 LVNLMSNYDVPEKWARFYTAEVVLALDAIHSMGFIHRDVKPDNMLLD-KSGHLKLADFGT 219
L ++YD+ RFY E++ ALD HSMG +HRDVKP N+++D ++ L+L D+G
Sbjct: 850 LYQTFTDYDI-----RFYLYELMKALDFCHSMGIMHRDVKPHNVMIDHENKKLRLIDWGL 1014
Query: 220 CMKMNKEGMVRCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTP 277
+ GM + V + + PE+L Y D WS+G M+ P
Sbjct: 1015A-EFYHPGM-EYNVRVASRYFKGPELLLDY---QMYDYSLDMWSLGCMFASMIFRKEP 1173
>17722
Length = 680
Score = 55.8 bits (133), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 38/109 (34%), Positives = 54/109 (49%), Gaps = 3/109 (2%)
Frame = -3
Query: 260 DWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLTFPDDNDISKEAKNLICAFLT- 318
DWW GV +YEM+ G PFY + I+ ++ FP ++S+EAK L+ L
Sbjct: 675 DWWGTGVVMYEMMCGRLPFYNRDHDVLFELIL--LQNVKFP--RNLSEEAKTLLSGLLAK 508
Query: 319 DREVRLGRN--GVEEIKRHLFFKNDQWAWETLRDTVAPVVPDLSSDIDT 365
+ + RLG + V EIK H FF+ W + P PD+ S DT
Sbjct: 507 NPKRRLGGSEADVTEIKTHPFFQCINWDDLAAKKITPPWKPDVKSSWDT 361
>29581
Length = 1278
Score = 55.5 bits (132), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 43/132 (32%), Positives = 61/132 (46%), Gaps = 2/132 (1%)
Frame = -2
Query: 149 LYMVMEYMPGGDLVNLMSNYDVP--EKWARFYTAEVVLALDAIHSMGFIHRDVKPDNMLL 206
L++VMEY DL +L+ N P E + +++ L +H IHRD+K N+L+
Sbjct: 1124 LFLVMEYC-EQDLASLLDNMPAPFSESQVKCIVLQLLKGLRYLHEAFIIHRDLKVSNLLM 948
Query: 207 DKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGV 266
G +K+ADFG K V T Y +PE+L G + D WS G
Sbjct: 947 TDKGCVKIADFGLARNYGKPQKPMTPKVV-TLWYRAPELL---FGSKTHSTAIDMWSAGC 780
Query: 267 FLYEMLVGDTPF 278
L E+L G P
Sbjct: 779 ILGELL-GHKPL 747
>11185
Length = 473
Score = 55.5 bits (132), Expect = 1e-07, Method: Composition-based stats.
Identities = 37/120 (30%), Positives = 53/120 (44%), Gaps = 21/120 (17%)
Frame = +1
Query: 176 RFYTAEVVLALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTCMK------------- 222
R + +V L IHS+G + D++P +LLD SG LK ADFG
Sbjct: 10 RDFGIHLVTGLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFA 189
Query: 223 --------MNKEGMVRCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVG 274
+ E M++ G+P Y++PEV QG + D W++G YEM G
Sbjct: 190 EAGDQWNIQSAEEMMKQVPTSGSPTYMAPEVF--QGAEPSI--MSDLWALGCVFYEMFSG 357
>19761
Length = 473
Score = 55.5 bits (132), Expect = 2e-07, Method: Composition-based stats.
Identities = 31/104 (29%), Positives = 53/104 (50%), Gaps = 2/104 (1%)
Frame = -3
Query: 170 VPEKWARFYTAEVVLALDAIHSMG--FIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEG 227
+PE+ + + AL+ +H+ +HRD+KP N+ + + G ++L D G K+
Sbjct: 432 LPERLIVCWLMQTASALNYMHTHTPVILHRDLKPQNIYVTEKGDVRLGDLGLARKLTGPA 253
Query: 228 MVRCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEM 271
+ VGT Y+SPE+L Q Y + D WS+G Y++
Sbjct: 252 DF-ATSQVGTIMYLSPEILSQQP----YNSKSDIWSLGCVFYDI 136
>27546
Length = 426
Score = 52.8 bits (125), Expect = 9e-07, Method: Composition-based stats.
Identities = 29/100 (29%), Positives = 54/100 (54%), Gaps = 1/100 (1%)
Frame = -1
Query: 120 FFWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVN-LMSNYDVPEKWARFY 178
FF E +I+ + P ++Q+ Q +++ M Y GD+++ + + E + +
Sbjct: 342 FFPRELEILTRLDHPNIIQIHSILQRGPKIFIFMRYAEKGDMLSHIKKTGPIDEAQTKVW 163
Query: 179 TAEVVLALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFG 218
++ AL +HS HRD+K +N+LL K ++K+ADFG
Sbjct: 162 FFQMAKALQYLHSHDIAHRDLKCENILLSKRLNVKIADFG 43
>00392
Length = 668
Score = 50.4 bits (119), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 40/171 (23%), Positives = 80/171 (46%), Gaps = 13/171 (7%)
Frame = +3
Query: 121 FWEERDIMAFANSPWVVQLF-----YAFQDDRYLYMVMEYMPGGDLVNLMSNYDVP---- 171
F EE +++ P +V+ F + ++ + + +V E M G L + + P
Sbjct: 72 FKEEAEMLKELQHPNIVRFFDYWEEHNHRNRKVIILVTELMTSGTLKTYLKRFKKPNVKI 251
Query: 172 -EKWARFYTAEVVLALDAIHSMG--FIHRDVKPDNMLL-DKSGHLKLADFGTCMKMNKEG 227
+ W R +V+ L +H+ IHRD+K DN+ + +G +K+ D G N+
Sbjct: 252 LKNWCR----QVLKGLYFLHTRTPPVIHRDLKCDNIFITGPTGSVKIGDLGLATLKNQSF 419
Query: 228 MVRCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPF 278
+ +GTP++++PE+ + +Y D ++ G+ + EM + P+
Sbjct: 420 A---KSVIGTPEFMAPEMYEE-----HYDEAVDVYAFGMCMLEMASSEYPY 548
>28157
Length = 400
Score = 50.4 bits (119), Expect = 5e-06, Method: Composition-based stats.
Identities = 35/107 (32%), Positives = 57/107 (53%), Gaps = 8/107 (7%)
Frame = +3
Query: 121 FWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKW----AR 176
F +E ++ + P +V L+ A +D + +VMEY GG L N++ ++ A
Sbjct: 51 FMQELKQLSRVSHPNIVCLYGACRD-HPVCLVMEYAEGGSLYNVLHGSGPQPQYTAAHAM 227
Query: 177 FYTAEVVLALDAIHSM---GFIHRDVKPDNMLLDKSG-HLKLADFGT 219
+ + L ++ +H M IHRD+KP N+LL + G LK+ DFGT
Sbjct: 228 NWLLQCALGVEYLHGMKPKALIHRDLKPPNLLLIQCGTKLKICDFGT 368
>00715
Length = 1788
Score = 48.5 bits (114), Expect = 2e-05, Method: Composition-based stats.
Identities = 38/162 (23%), Positives = 70/162 (43%), Gaps = 23/162 (14%)
Frame = +1
Query: 140 FYAFQDDRYLYMVMEYMPGGDLVNLMSNY--DVPEKWARFYTAEVVLALDAIHSMGFIHR 197
+ F+D +L MEY+ +L +++++ D+ ++ L +HS+ +H
Sbjct: 139 LHRFEDGAWL--AMEYVGPLNLQTILNDHQQDIDSSMRLSLALQMARGLHYLHSINIVHL 312
Query: 198 DVKPDNMLLDKSGHLKLADFGTCMKMNKEGM---------------------VRCDTAVG 236
D+KP N LL + L++ADFG C ++ G+ + G
Sbjct: 313 DLKPANCLLTRDLKLRIADFGCCHQLTPTGLDMGEREGGMAGNELELTPVQGAWKNELAG 492
Query: 237 TPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPF 278
T Y +PE+LK D +S+G+ L++M P+
Sbjct: 493 TLAYRAPELLKGLQPS----VRSDVYSLGITLWQMCTRQGPY 606
>04138
Length = 800
Score = 48.5 bits (114), Expect = 2e-05, Method: Composition-based stats.
Identities = 33/85 (38%), Positives = 40/85 (47%), Gaps = 2/85 (2%)
Frame = +1
Query: 189 IHSMGFIHRDVKPDNMLLDKSGHLKLADFG--TCMKMNKEGMVRCDTAVGTPDYISPEVL 246
IH +HRD+K N+L+ K G LKLADFG +N R V T Y PE+L
Sbjct: 61 IHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRPPELL 240
Query: 247 KSQGGDGYYGRECDWWSVGVFLYEM 271
GD Y D W G + EM
Sbjct: 241 L---GDRNYSTAIDQWGAGCIMAEM 306
>01966
Length = 1735
Score = 48.1 bits (113), Expect = 2e-05, Method: Composition-based stats.
Identities = 46/162 (28%), Positives = 75/162 (46%), Gaps = 9/162 (5%)
Frame = -1
Query: 94 RHKSTRKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFAN--SPWVVQLFYAFQDDRYLYM 151
RH++T + AMK K + D R+I +V L +D L++
Sbjct: 1651 RHRATGRKLAMK---KIRLRGSEDGVPSSAIREIAMLRELRHTNIVCLEDVIMEDERLFL 1481
Query: 152 VMEYMPGGDLVNLMSNYDVPE------KWARFYTAEVVLALDAIHSMGFIHRDVKPDNML 205
V E++ DL + + PE + + Y ++V ++ H +HRD+KP N+L
Sbjct: 1480 VFEFL-SMDLKMYIDKF--PEGVVLDRRLVKSYVFQIVTGINFCHQRRIVHRDLKPQNLL 1310
Query: 206 LDKSGHLKLADFGTCMKMNKEGMVRCDT-AVGTPDYISPEVL 246
++ +G +K+ADFG M VR T V T Y +PE+L
Sbjct: 1309 INHTGAIKIADFG--MARTFALPVRAYTHEVVTLWYRAPEIL 1190
>19301
Length = 712
Score = 47.4 bits (111), Expect = 4e-05, Method: Compositional matrix adjust.
Identities = 22/70 (31%), Positives = 43/70 (61%), Gaps = 1/70 (1%)
Frame = +2
Query: 151 MVMEYMPGGDLVNLMSNY-DVPEKWARFYTAEVVLALDAIHSMGFIHRDVKPDNMLLDKS 209
++MEY P G L ++ + ++P ++ ++ ++ +HS IHRD+K N+L+ K+
Sbjct: 500 IIMEYCPYGQLYEVLRDGKEIPPALVLDWSKQIASGMNYLHSHKIIHRDLKSPNVLVAKN 679
Query: 210 GHLKLADFGT 219
+K++DFGT
Sbjct: 680 DVVKISDFGT 709
>37063
Length = 455
Score = 47.4 bits (111), Expect = 4e-05, Method: Composition-based stats.
Identities = 27/78 (34%), Positives = 45/78 (57%), Gaps = 8/78 (10%)
Frame = -2
Query: 199 VKPDNML---LDKSGHLKLADFGTCMKMNKEG----MVRCDTAVGTPDYISPEVLKSQGG 251
+KP+N+L LD+ LK+ DF +N +G T VG+ +Y++PEV+ + G
Sbjct: 454 LKPENILCEHLDEVVPLKICDFDLASGINCDGDGTKTPELLTPVGSAEYMAPEVVDAWVG 275
Query: 252 DGY-YGRECDWWSVGVFL 268
+ + Y + CD WS+G+ L
Sbjct: 274 ESFSYDKRCDMWSLGIIL 221
>14116
Length = 1017
Score = 47.4 bits (111), Expect = 4e-05, Method: Compositional matrix adjust.
Identities = 36/126 (28%), Positives = 63/126 (50%), Gaps = 4/126 (3%)
Frame = -1
Query: 151 MVMEYMPGGDLVNLMSN--YDVPEKWARFYTAEVVLALDAIHSMGFIHRDVKPDNMLLDK 208
+V+ +M GDL+ + + + K Y ++ +D + + F+HRD+ N +LD+
Sbjct: 393 VVLPFMKHGDLLTYIRDDQHQPTIKDLIMYGVDIARGMDYLAGLKFVHRDLAARNCMLDE 214
Query: 209 SGHLKLADFGTCMKM-NKEGMVRCDTAVGTP-DYISPEVLKSQGGDGYYGRECDWWSVGV 266
H+K+ADFG + KE + P +++ E L+ G Y + D WS GV
Sbjct: 213 DFHVKVADFGLARDIYEKEYYSSENKKAKLPVKWMALESLEK----GNYDSKTDVWSYGV 46
Query: 267 FLYEML 272
L+E+L
Sbjct: 45 VLWELL 28
>37602
Length = 804
Score = 46.2 bits (108), Expect = 9e-05, Method: Composition-based stats.
Identities = 28/86 (32%), Positives = 43/86 (50%), Gaps = 5/86 (5%)
Frame = -1
Query: 137 VQLFYAFQDD----RYLYMVMEYMPGGDLVNLMS-NYDVPEKWARFYTAEVVLALDAIHS 191
+Q F + D L++ MEY GG + ++ + E F E + L +H
Sbjct: 342 IQTFVGYFDSYLRREKLWIAMEYCGGGSMQDIYHVTGPLTEPQIAFVCRETLKGLHYLHR 163
Query: 192 MGFIHRDVKPDNMLLDKSGHLKLADF 217
G +HRD+K N+LL + G +KLADF
Sbjct: 162 RGKMHRDIKGANILLTEEGDVKLADF 85
>21808
Length = 1011
Score = 45.4 bits (106), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 41/165 (24%), Positives = 69/165 (41%), Gaps = 7/165 (4%)
Frame = +1
Query: 121 FWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKWARFY-- 178
F E IM P ++QL+ D ++++ E M G L+ + K
Sbjct: 73 FLAEAQIMKKLRHPKLIQLYAVCTQDDPIFIITELMKNGSLLEFLQGKGRVLKLPALIDI 252
Query: 179 TAEVVLALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGTP 238
A++ + + S +IHRD+ N+L+ + +K+ADFG ++ KE P
Sbjct: 253 GAQIACGMAYLESQNYIHRDLAARNILVSDNNTVKIADFGLA-RVIKEDEYEARVGARFP 429
Query: 239 -DYISPEVLKSQGGDGYYGR---ECDWWSVGVFLYEMLV-GDTPF 278
+ +PE Y R + D WS G+ L E + G P+
Sbjct: 430 IKWTAPEAAN-------YNRFTIKSDVWSFGILLTETVTYGRVPY 543
>07940
Length = 1336
Score = 44.3 bits (103), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 32/103 (31%), Positives = 51/103 (49%), Gaps = 2/103 (1%)
Frame = -3
Query: 178 YTAEVVLALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGT 237
Y +V ++ + S IHRD+ N+L+ + LK+ADFG + + R T
Sbjct: 332 YAYQVARGMEYLASKQCIHRDLAARNVLVAEEYVLKIADFGLTRNLQQFDYYRKTTDGRL 153
Query: 238 P-DYISPEVLKSQGGDGYYGRECDWWSVGVFLYEML-VGDTPF 278
P +++PE L D Y + D WS GV L+E+ +G P+
Sbjct: 152 PVKWMAPEALF----DRKYTSKSDVWSYGVLLWEIFTLGGNPY 36
>32359
Length = 928
Score = 34.3 bits (77), Expect(2) = 4e-04, Method: Compositional matrix adjust.
Identities = 33/131 (25%), Positives = 59/131 (45%), Gaps = 11/131 (8%)
Frame = -1
Query: 76 YEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSPW 135
Y KVIG G+FG V + T ++ A+K + + D F E IM
Sbjct: 424 YTDAKVIGNGSFGVVYQAKLVDTSELVAIKKVLQ-------DKRFKNRELQIMRKLEHQN 266
Query: 136 VVQLFYAF------QDDRYLYMVMEYMPGGDLVNLMSNYD-----VPEKWARFYTAEVVL 184
+V+L + F +D+ +L +V+EY+P + + +Y +P + + Y ++
Sbjct: 265 IVKLKFFFYSSGEKKDEVFLNLVLEYVP-ETVYRVARHYSKSKQTIPILYIKLYMYQLFR 89
Query: 185 ALDAIHSMGFI 195
+L IHS +
Sbjct: 88 SLAYIHSQACV 56
Score = 28.5 bits (62), Expect(2) = 4e-04, Method: Composition-based stats.
Identities = 10/15 (66%), Positives = 12/15 (80%)
Frame = -3
Query: 193 GFIHRDVKPDNMLLD 207
G HRD+KP N+LLD
Sbjct: 65 GVCHRDIKPQNLLLD 21
>07833
Length = 1504
Score = 43.9 bits (102), Expect = 4e-04, Method: Composition-based stats.
Identities = 37/169 (21%), Positives = 73/169 (43%), Gaps = 11/169 (6%)
Frame = -3
Query: 121 FWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLM---SNYDVPEKWARF 177
F EE + N P V+ + L ++ ++MP G L N + S V + +
Sbjct: 1478 FMEEFPRLRIFNHPNVLPVLACCNQPPNLVLISQFMPFGSLYNTLHGESGIVVDQNQSLR 1299
Query: 178 YTAEVVLALDAIHSMGFIHRDVKPDNMLLDK--------SGHLKLADFGTCMKMNKEGMV 229
+ ++ ++ +HSM P+ +L K + + +AD+ C +++G V
Sbjct: 1298 FAMDIARGMEFLHSM----EPTIPNFLLTSKHVMIDEDLTARINMADY--CFSFHEKGKV 1137
Query: 230 RCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPF 278
+P +++PE L+ + D R D WS + ++E+ + PF
Sbjct: 1136 Y------SPAWMAPEALQRRPDD-INTRAADMWSFAILMWELETREVPF 1011
>06358
Length = 1517
Score = 43.5 bits (101), Expect = 6e-04, Method: Compositional matrix adjust.
Identities = 47/171 (27%), Positives = 72/171 (42%), Gaps = 14/171 (8%)
Frame = +3
Query: 123 EERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKWARFYTAEV 182
E R+ +AFA P L D + V + + L YDV K E
Sbjct: 237 ESRETLAFATEPVFASLANVLGDLSSIXTVPKELQDYQL------YDVEIKHGLLQVTE- 395
Query: 183 VLALDAIHS-MGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMV---------RCD 232
AL +H+ +HR+V P+ ++L K G KLA + C++ + R D
Sbjct: 396 --ALGFLHNDAKMMHRNVCPEAIMLTKLGSWKLAGYEFCVRSSDPQSTDPSYPFYEWRSD 569
Query: 233 TA-VGTP--DYISPE-VLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFY 279
A V P D+++PE VL Q G G D +S+G+ +Y + P +
Sbjct: 570 IAPVTQPHLDFMAPEYVLTMQCGTG-----SDMFSLGLLVYSVFAKGKPLF 707
>32957
Length = 645
Score = 43.1 bits (100), Expect = 8e-04, Method: Composition-based stats.
Identities = 18/43 (41%), Positives = 28/43 (65%)
Frame = +3
Query: 230 RCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEML 272
R T GT +Y++PEV + + YG+E DWW +G+ L+E+L
Sbjct: 33 RTRTFCGTREYMAPEVHERK----EYGKEVDWWGLGILLHELL 149
>00638
Length = 1595
Score = 43.1 bits (100), Expect = 8e-04, Method: Composition-based stats.
Identities = 23/60 (38%), Positives = 35/60 (58%), Gaps = 3/60 (5%)
Frame = +2
Query: 151 MVMEYMPGGDLVNL---MSNYDVPEKWARFYTAEVVLALDAIHSMGFIHRDVKPDNMLLD 207
++ E++ D L ++YD+ RFY E++ ALD HSMG +HRDVKP L++
Sbjct: 356 LIFEHVNNTDFKQLYQTFTDYDI-----RFYLYELMKALDFCHSMGIMHRDVKPSPPLVN 520
>14748
Length = 606
Score = 42.4 bits (98), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 35/111 (31%), Positives = 63/111 (56%)
Frame = +3
Query: 527 KKVSQNSQLANEKLSQLQKQLEEANDLLRTESDTAVRLRKSHTEMSKSISQLESLNRELQ 586
++++++S ++E+L+ ++K L EAN LRTE D A + +K+ ++M + + E EL
Sbjct: 231 QEINRDSVQSSERLASVEKSLNEANVKLRTEMDHANKQKKAMSDMQQRLMNAEQNYGELT 410
Query: 587 ERNRILENSKSQTDKDYYQLQAILEAERRDRGHDSEMIGDLQARITSLQEE 637
R + L K + + + LQA L+ ER R + +L RI +LQ+E
Sbjct: 411 GRYQDLNALKQRMETEVLTLQASLDVERNARSQEVAHTMELNERIKALQDE 563
>04852
Length = 1462
Score = 42.4 bits (98), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 40/151 (26%), Positives = 71/151 (47%), Gaps = 6/151 (3%)
Frame = +1
Query: 157 PGGDLV---NLMSNYDVPEKWARFYTAEVVLALDAIHSMGFIHRDVKPDNMLLDKSGHLK 213
PGG ++ NL+S Y ++ ++ + S IHRD+ N+L+ + LK
Sbjct: 301 PGGHVIRRKNLLS-----------YAFQIARGMEFLASRKCIHRDLAARNVLVTEEHVLK 447
Query: 214 LADFGTCMKMNKEGMVRCDTAVG--TPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEM 271
+ADFG +++ G + G +++PE L D Y + D WS GV L+E+
Sbjct: 448 IADFG----LSRTGDYYKKRSGGRLPVKWMAPEALF----DMRYTTKSDVWSFGVVLWEI 603
Query: 272 L-VGDTPFYADSLVGTYSKIMNHKNSLTFPD 301
+G P+ + YSK+++ + P+
Sbjct: 604 FSLGGMPYASIPNEELYSKLLDDAYRMPRPE 696
>12672
Length = 773
Score = 42.4 bits (98), Expect = 0.001, Method: Composition-based stats.
Identities = 27/85 (31%), Positives = 41/85 (48%), Gaps = 3/85 (3%)
Frame = +3
Query: 193 GFIHRDVKPDNMLLDKSGHLKLADFGTCMKM-NKEGMV--RCDTAVGTPDYISPEVLKSQ 249
G +HRD+K N+LLD K+ DF T + + EG +GT Y++PE +
Sbjct: 51 GHVHRDIKTANILLDSEYTAKVGDFATVVSAPSGEGKTVQNASVVIGTAAYLAPEAIHFD 230
Query: 250 GGDGYYGRECDWWSVGVFLYEMLVG 274
+ D +S GV L E++ G
Sbjct: 231 -----VSTKLDSYSFGVVLLEVITG 290
>29590
Length = 320
Score = 42.0 bits (97), Expect = 0.002, Method: Composition-based stats.
Identities = 23/55 (41%), Positives = 30/55 (54%)
Frame = +3
Query: 235 VGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSK 289
+GTPDY++PEVL + + D WS+GV Y ML +PF VG SK
Sbjct: 57 IGTPDYVAPEVLDYEP----LSIQTDMWSLGVLSYVMLTACSPF-----VGITSK 194
>11780
Length = 1713
Score = 41.6 bits (96), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 36/151 (23%), Positives = 74/151 (49%), Gaps = 3/151 (1%)
Frame = +3
Query: 71 MKAEDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAFFWEERDIMAF 130
+ +D E+ + IG+G FG+V ++ + A+K L + ++S F +E +M
Sbjct: 588 IAXQDLEIGEAIGKGDFGDVYKGMYRG--QPVAIKQLKDKDRGEQS----FLQEASVMTS 749
Query: 131 ANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYD---VPEKWARFYTAEVVLALD 187
+V+L + +++V E+M G+LV + + + +K + + A++
Sbjct: 750 LRHDNLVRLIGVVLGET-IFLVTEFMGKGNLVEYLRSRGRSVITKKDQINFATDTCAAME 926
Query: 188 AIHSMGFIHRDVKPDNMLLDKSGHLKLADFG 218
+ S +HRD+ N+L+ G K++DFG
Sbjct: 927 YLESKRLVHRDLAARNVLVHDDGKAKVSDFG 1019
>18996
Length = 491
Score = 40.4 bits (93), Expect = 0.005, Method: Composition-based stats.
Identities = 29/85 (34%), Positives = 44/85 (51%), Gaps = 2/85 (2%)
Frame = +2
Query: 195 IHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGTP-DYISPEVLKSQGGDG 253
IHRD+ N+L+D+S +K++DFG N +G + P + SPE +++
Sbjct: 2 IHRDLAARNILVDRSC-VKISDFGLAQFANADGYYYGISQRDIPIKWYSPEAIETCKFSS 178
Query: 254 YYGRECDWWSVGVFLYEMLV-GDTP 277
Y D WS GV L+EM G+ P
Sbjct: 179 Y----SDVWSYGVTLFEMFSRGEIP 241
>02638
Length = 1490
Score = 40.4 bits (93), Expect = 0.005, Method: Composition-based stats.
Identities = 21/66 (31%), Positives = 34/66 (51%)
Frame = +1
Query: 235 VGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHK 294
+GT +++PEVL+ + YGR CD WSVG + EM P+ + + + I
Sbjct: 19 LGTIAFMAPEVLRGES----YGRACDVWSVGCVMIEMCTCRPPWNSHDISNHLALIFKIA 186
Query: 295 NSLTFP 300
+S+ P
Sbjct: 187 SSVDPP 204
>17300
Length = 480
Score = 40.0 bits (92), Expect = 0.007, Method: Composition-based stats.
Identities = 25/99 (25%), Positives = 48/99 (48%), Gaps = 4/99 (4%)
Frame = +1
Query: 185 ALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGTP---DYI 241
+ + MG++HRD+ N+L+++ K+ADFG ++ + T G +
Sbjct: 10 GMGXLADMGYVHRDLAARNILVNEILVCKVADFGLSREIESDTTEGAYTTKGGKIPVRWT 189
Query: 242 SPEVLKSQGGDGYYGRECDWWSVGVFLYE-MLVGDTPFY 279
+PE + + + D WS GV ++E M G+ P++
Sbjct: 190 APEAIAYRK----FTSASDVWSFGVVMWEVMSYGERPYW 294
>07291
Length = 833
Score = 39.7 bits (91), Expect = 0.009, Method: Compositional matrix adjust.
Identities = 22/87 (25%), Positives = 45/87 (51%), Gaps = 3/87 (3%)
Frame = +1
Query: 195 IHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCD--TAVGTPDYISPEVLKSQGGD 252
+HR++ N ++ + G L+L+D+G + + D A +++PE + +
Sbjct: 115 VHRNLAARNCIVTEDGRLQLSDYGVTGSLFPQSYYTADDSPARDLVKWMAPETID----N 282
Query: 253 GYYGRECDWWSVGVFLYEMLV-GDTPF 278
++ + D W+ GV L+E+L G TP+
Sbjct: 283 FHFSSKSDVWAFGVVLWELLTRGITPY 363
>11404
Length = 563
Score = 38.9 bits (89), Expect = 0.013, Method: Compositional matrix adjust.
Identities = 39/153 (25%), Positives = 68/153 (44%), Gaps = 19/153 (12%)
Frame = +1
Query: 73 AEDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSK--------------FEMIKRSDS 118
A+ YE+ +IG+G+FG+V + + A+K++ EM+ R D+
Sbjct: 136 ADRYEIDSLIGKGSFGQVVKAYDHTDNEQVAIKIIKNKKPFLNQAQIEVKLLEMMNRHDT 315
Query: 119 AFFWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYD---VPEKWA 175
N ++V+L F +L +V E + +L +L+ N + V
Sbjct: 316 ------------DNKYYIVRLKRHFMFRSHLCLVFELL-SYNLYDLLRNTNFRGVSLNLT 456
Query: 176 RFYTAEVVLAL--DAIHSMGFIHRDVKPDNMLL 206
R + ++ AL A M IH D+KP+N+LL
Sbjct: 457 RKFAQQLCTALLFLATPEMSIIHCDLKPENILL 555
>13840
Length = 446
Score = 38.9 bits (89), Expect = 0.014, Method: Compositional matrix adjust.
Identities = 38/134 (28%), Positives = 59/134 (44%), Gaps = 7/134 (5%)
Frame = -1
Query: 73 AEDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMK-LLSKFEMIKRSDSAFFWEERDIMAFA 131
+ED + + IGRG +G V +RHK T V A+K + S E +R + +M
Sbjct: 398 SEDMQDMGEIGRGNYGTVNKMRHKITSTVMAVKRIRSTVE--EREQKQLLMDLDVVMRSN 225
Query: 132 NSPWVVQLFYAFQDDRYLYMVMEYMPGG-----DLVNLMSNYDVPEKWARFYTAEVVLAL 186
N P++VQ + A + ++ ME M V +PE T + AL
Sbjct: 224 NCPFIVQFYGALFKEGDCWICMELMETSLDKFYKFVYGEMQSSIPENILGKITVATLKAL 45
Query: 187 DAI-HSMGFIHRDV 199
+ + + IHRDV
Sbjct: 44 NYLKEELRIIHRDV 3
>33586
Length = 551
Score = 38.9 bits (89), Expect = 0.015, Method: Composition-based stats.
Identities = 19/49 (38%), Positives = 32/49 (65%), Gaps = 1/49 (2%)
Frame = +2
Query: 135 WVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDV-PEKWARFYTAEV 182
++V L YAFQ + LY+++E++ GGDL +S + E+ +FY AE+
Sbjct: 404 FIVHLHYAFQTEGKLYLILEFLRGGDLFTRLSKEVMFTEEDVKFYLAEL 550
>18401
Length = 463
Score = 38.5 bits (88), Expect = 0.017, Method: Compositional matrix adjust.
Identities = 18/46 (39%), Positives = 24/46 (52%)
Frame = -3
Query: 233 TAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPF 278
T V T Y +PEV+ G + CD WSVG ++E+ G T F
Sbjct: 455 TIVSTRHYRAPEVILELG----WSHPCDVWSVGCIMFELYTGYTLF 330
>29360
Length = 363
Score = 38.5 bits (88), Expect = 0.021, Method: Compositional matrix adjust.
Identities = 22/72 (30%), Positives = 37/72 (51%), Gaps = 2/72 (2%)
Frame = +3
Query: 137 VQLFYAFQDDRYLYMVMEYMPGG--DLVNLMSNYDVPEKWARFYTAEVVLALDAIHSMGF 194
V+ F FQ + +V E + D + +P K+ R T +V+ AL + +G
Sbjct: 144 VRAFECFQHKNHTCLVFEMLEQNLYDFLKQNKFQPLPLKYIRPITQQVLTALRKLKQLGL 323
Query: 195 IHRDVKPDNMLL 206
IH D+KP+N++L
Sbjct: 324 IHADLKPENIML 359
>20152
Length = 445
Score = 37.4 bits (85), Expect = 0.041, Method: Composition-based stats.
Identities = 20/50 (40%), Positives = 28/50 (56%)
Frame = +1
Query: 243 PEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMN 292
PE+L GD Y D WS+GV LY ++VG+ PF + T + IM+
Sbjct: 1 PEILL---GDSYDAPAVDVWSLGVILYMLVVGEAPFQEANDSETLTMIMD 141
>25829
Length = 543
Score = 37.0 bits (84), Expect = 0.048, Method: Compositional matrix adjust.
Identities = 39/126 (30%), Positives = 60/126 (47%)
Frame = +3
Query: 536 ANEKLSQLQKQLEEANDLLRTESDTAVRLRKSHTEMSKSISQLESLNRELQERNRILENS 595
AN + SQLQ Q E++ LR + VRL + +S+ + LE + L E R L++
Sbjct: 123 ANSRCSQLQNQDAESSRELRNLTRQHVRLEEEKKHLSRDYATLEQKMQLLTEEKRQLQDQ 302
Query: 596 KSQTDKDYYQLQAILEAERRDRGHDSEMIGDLQARITSLQEEVKHLKHNLEKVEGERKEA 655
++T K+ +LQ +E DRG S SLQ+++ + L KV+G K
Sbjct: 303 LAETKKEVSRLQECME----DRGKSS----------VSLQDKLTAAEKELSKVKGPMKRH 440
Query: 656 QDMLNH 661
D H
Sbjct: 441 PDPPGH 458
>18481
Length = 437
Score = 37.0 bits (84), Expect = 0.049, Method: Composition-based stats.
Identities = 28/114 (24%), Positives = 50/114 (43%), Gaps = 4/114 (3%)
Frame = -1
Query: 109 KFEMIKRSDSAFFWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYM-PGGDLVNLMSN 167
K E I +E + P + +++ + + +VME + P + + ++
Sbjct: 392 KIEAIDVKHQLLHYEAKVYEQIGRHPGLPTMYHYGTEKHFNALVMELLGPSLEELFVICK 213
Query: 168 YDVPEKWARFYTAEVVLALDAIHSMGFIHRDVKPDNMLLDKSGH---LKLADFG 218
K + +++ L+ IH FIHRD+KPDN L+ H L + DFG
Sbjct: 212 RRFTLKTILMVSDQLLSRLEFIHQKCFIHRDLKPDNFLMGLGRHCHRLYIIDFG 51
>26009
Length = 886
Score = 36.6 bits (83), Expect = 0.079, Method: Compositional matrix adjust.
Identities = 17/36 (47%), Positives = 23/36 (63%)
Frame = +2
Query: 74 EDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSK 109
E Y+V K +GRG +G+V L R + T A+KLL K
Sbjct: 416 EHYDVCKELGRGTYGKVVLARCRHTGTQVALKLLPK 523
Score = 35.0 bits (79), Expect = 0.20, Method: Composition-based stats.
Identities = 14/32 (43%), Positives = 23/32 (71%)
Frame = +3
Query: 175 ARFYTAEVVLALDAIHSMGFIHRDVKPDNMLL 206
A+ ++V ALD +HS +HRD+KP+N+L+
Sbjct: 717 AKSVMKQLVSALDFMHSKQLVHRDIKPENVLI 812
>31489
Length = 329
Score = 36.2 bits (82), Expect = 0.086, Method: Composition-based stats.
Identities = 20/67 (29%), Positives = 39/67 (58%), Gaps = 1/67 (1%)
Frame = +3
Query: 140 FYAFQDDRYLYMVMEYMPGGDLVNLM-SNYDVPEKWARFYTAEVVLALDAIHSMGFIHRD 198
++ F+D ++ +ME DL ++ S+ + E+ R++ +++ L IHS +HRD
Sbjct: 75 YHDFKDIHVVFDLME----SDLHRIIYSDQPLTEEHIRYFLYQILRGLKYIHSANVVHRD 242
Query: 199 VKPDNML 205
+KP N+L
Sbjct: 243 LKPSNLL 263
>01106
Length = 878
Score = 35.8 bits (81), Expect = 0.11, Method: Compositional matrix adjust.
Identities = 37/146 (25%), Positives = 70/146 (47%), Gaps = 15/146 (10%)
Frame = +3
Query: 76 YEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAF-------FWEERDIM 128
Y V++ +G G F V L + ++ A+K++ + +++A E D+
Sbjct: 324 YHVIRKLGWGHFSTVWLCWDLTCKRFVALKVVKSAQHY--TETALDEVKLLKCVRESDVA 497
Query: 129 AFANSPWVVQLFYAFQ----DDRYLYMVMEYMPGGDLVNLM--SNY-DVPEKWARFYTAE 181
A + VQL F+ + ++ MV E + G +L+ L+ SNY +P + +
Sbjct: 498 DPARAK-CVQLLDDFKISGVNGTHVAMVFEVL-GYNLLKLIIRSNYQGIPIHNVKLIIRQ 671
Query: 182 VVLALDAIHS-MGFIHRDVKPDNMLL 206
V+ L +H+ IH D+KP+N+L+
Sbjct: 672 VLEGLSYMHAKCRIIHTDIKPENILI 749
>17516
Length = 453
Score = 33.1 bits (74), Expect = 0.71, Method: Composition-based stats.
Identities = 16/42 (38%), Positives = 25/42 (59%)
Frame = -3
Query: 233 TAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVG 274
T GTP Y++PEVL + G Y + D +S+ + L+E+ G
Sbjct: 442 TLAGTPVYMAPEVLLQK---GQYDMKADVYSLAIILWELWYG 326
>28040
Length = 433
Score = 32.7 bits (73), Expect = 1.0, Method: Compositional matrix adjust.
Identities = 45/124 (36%), Positives = 68/124 (54%), Gaps = 5/124 (4%)
Frame = +3
Query: 569 TEMSKSISQLESLNRELQERNRILENSKSQTDKDYYQLQAILEAERRDRGHDSEMIGDLQ 628
++MS +S +ESL L R+ LE SQT+ QL+ L +ER + E+ G LQ
Sbjct: 24 SQMSSMLSTMESLQGTLSARDSELEQLMSQTE----QLKEKL-SEREE-----EVTG-LQ 170
Query: 629 ARITSLQEEVKHLKHNLEKV-EGERKEAQDM---LNHSEKEKNNLEIDLNY-KLKSLQQR 683
A + SLQ+ + K +LE V E AQD+ ++ EK ++ LE +L K K+L+Q+
Sbjct: 171 ASLGSLQDVIAMTKSDLEAVTEDYNDRAQDLEAQISELEKRRDQLETELETEKAKNLEQK 350
Query: 684 LEQE 687
E E
Sbjct: 351 EELE 362
>27274
Length = 396
Score = 32.7 bits (73), Expect = 1.1, Method: Composition-based stats.
Identities = 17/56 (30%), Positives = 30/56 (53%), Gaps = 8/56 (14%)
Frame = -1
Query: 244 EVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPF--------YADSLVGTYSKIM 291
E+L+ Q +G D WS+G+ L+E+L G PF A +++ Y++I+
Sbjct: 375 ELLRGQ----QHGPTVDMWSLGILLHELLSGHVPFEPERGSRQMARNMMAVYAQII 220
>20640
Length = 1492
Score = 32.3 bits (72), Expect = 1.3, Method: Composition-based stats.
Identities = 23/91 (25%), Positives = 40/91 (43%), Gaps = 3/91 (3%)
Frame = +1
Query: 193 GFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPDYISP--EVLKSQG 250
G++HRD+ N L+ +K++DFG ++ R P P +L ++
Sbjct: 4 GYVHRDLATRNCLVGHDLVVKISDFGLARSVHSVDYYRGSEHDAIPIRWMPLEAILYNK- 180
Query: 251 GDGYYGRECDWWSVGVFLYEMLV-GDTPFYA 280
+ + D WS GV L+E+ P+Y
Sbjct: 181 ----FSTQSDVWSFGVVLWEIFAFALQPYYG 261
>32357
Length = 625
Score = 30.8 bits (68), Expect = 3.8, Method: Composition-based stats.
Identities = 13/36 (36%), Positives = 21/36 (58%), Gaps = 6/36 (16%)
Frame = -3
Query: 174 WARFYTAEVVLALDA------IHSMGFIHRDVKPDN 203
WA+ + V++ D +++ FIHRD+KPDN
Sbjct: 170 WAQIHHETVLMLADQMINRLELYTTNFIHRDLKPDN 63
>17623
Length = 687
Score = 30.8 bits (68), Expect = 3.9, Method: Compositional matrix adjust.
Identities = 16/52 (30%), Positives = 26/52 (50%), Gaps = 3/52 (5%)
Frame = +2
Query: 1290 TSARDMLLLACSQDEQKKWVTHLVKKIPKNPPSGFV---RASPRTLSTRSTA 1338
S +D L C + + TH++ +P PP G V R +P+ ST+ +A
Sbjct: 485 VSMKDPLYRPCPVSQLCNYSTHILFHLPTPPPPGHVRRHRQTPQ*TSTQHSA 640
>21210
Length = 518
Score = 29.6 bits (65), Expect = 8.1, Method: Composition-based stats.
Identities = 13/43 (30%), Positives = 21/43 (48%)
Frame = +3
Query: 236 GTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPF 278
G Y++PE + + Y D WS+G+ L E+ G P+
Sbjct: 6 GCRPYMAPERIDPRASSHGYDVRSDVWSLGITLMELATGRFPY 134
>30339
Length = 384
Score = 29.6 bits (65), Expect = 8.4, Method: Composition-based stats.
Identities = 11/27 (40%), Positives = 17/27 (62%)
Frame = -2
Query: 70 RMKAEDYEVVKVIGRGAFGEVQLVRHK 96
R D+ +KV+G+G+FG+V L K
Sbjct: 86 RFHLHDFNFIKVLGKGSFGKVMLAERK 6
>11353
Length = 454
Score = 29.6 bits (65), Expect = 9.4, Method: Composition-based stats.
Identities = 23/76 (30%), Positives = 30/76 (39%), Gaps = 3/76 (3%)
Frame = +1
Query: 1229 HEFIPTLYHFPANCDACAKPLWHVFKPPPALECRRCHVKCHRDHLDKKEDLI---CPCKV 1285
H F Y P CD C + LW K C C CH DK + L+ C
Sbjct: 142 HRFEKYTYTTPTYCDFCQQLLWGFSK--TGTHCVDCGYNCH----DKCQPLVPKTCSKLK 303
Query: 1286 SYDVTSARDMLLLACS 1301
S TSA+ +++ S
Sbjct: 304 SVSDTSAQSAVIVTRS 351
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000364721 | hsapiens_gene_ensembl |
Microtubule-associated protein RP/EB family member 1 (APC-binding
protein EB1) (End-binding protein 1) (EB1).
[Source:Uniprot/SWISSPROT;Acc:Q15691]
(268 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
02149 286 7e-78
06997 72 2e-13
09949 67 1e-11
28710 65 2e-11
>02149
Length = 1269
Score = 286 bits (731), Expect = 7e-78, Method: Compositional matrix adjust.
Identities = 150/265 (56%), Positives = 187/265 (70%), Gaps = 11/265 (4%)
Frame = +3
Query: 1 MAVNVYSTSVTSDNLSRHDMLAWINESLQLNLTKIEQLCSGAAYCQFMDMLFPGSIALKK 60
MAVNV+STS TSDNLSRHD++AW+N+SLQ + KIE+LC+GAAYCQFMDMLFPG++ALKK
Sbjct: 69 MAVNVHSTSCTSDNLSRHDIIAWVNDSLQTSYGKIEELCTGAAYCQFMDMLFPGTLALKK 248
Query: 61 VKFQAKLEHEYIQNFKILQAGFKRMGVDKIIPVDKLVKGKFQDNFEFVQWFKKFFDANYD 120
KF KLEHEYIQNFK+LQ F ++GVDK+IPV++LVKG+FQDNFEFVQWFK+FFDAN
Sbjct: 249 AKFNTKLEHEYIQNFKLLQNNFGKLGVDKVIPVERLVKGRFQDNFEFVQWFKRFFDANNK 428
Query: 121 GKDYDPVAARQGQETAVAPSLVAPALNK--------PKKPLTSSSAAPQRPISTQRTAAA 172
G DYDP++AR G+ A ALNK PK + S P RP + +
Sbjct: 429 GLDYDPLSARGGEPMGGANK---GALNKAPSNRTAPPKTRVPPSRTTPARPAANN--VRS 593
Query: 173 PKAGPGVVRKNPGVGNG---DDEAAELMQQVNVLKLTVEDLEKERDFYFGKLRNIELICQ 229
P + P N G+ +D AEL Q L + E LEKERDFYFGKLR+IE+ICQ
Sbjct: 594 PMSKP---TSNHAAGDSPMVEDLRAELRQ----LTVEKEGLEKERDFYFGKLRDIEVICQ 752
Query: 230 ENEGENDPVLQRIVDILYATDEGFV 254
E+ E+D ++ I+DILYAT++GF
Sbjct: 753 EH--EDDVSMKAIMDILYATEDGFA 821
>06997
Length = 583
Score = 72.4 bits (176), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 43/110 (39%), Positives = 61/110 (55%)
Frame = +1
Query: 144 PALNKPKKPLTSSSAAPQRPISTQRTAAAPKAGPGVVRKNPGVGNGDDEAAELMQQVNVL 203
PA N + P++ +P S +P +D AE+ Q+ L
Sbjct: 1 PAANNVRSPMS-------KPTSNHAAGDSPMV--------------EDLRAEVCAQLRQL 117
Query: 204 KLTVEDLEKERDFYFGKLRNIELICQENEGENDPVLQRIVDILYATDEGF 253
+ E LEKERDFYFGKLR+IE+ICQE+ E+D ++ I+DILYAT++GF
Sbjct: 118 TVEKEGLEKERDFYFGKLRDIEVICQEH--EDDVSMKAIMDILYATEDGF 261
>09949
Length = 455
Score = 66.6 bits (161), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 37/64 (57%), Positives = 48/64 (75%)
Frame = -1
Query: 190 DDEAAELMQQVNVLKLTVEDLEKERDFYFGKLRNIELICQENEGENDPVLQRIVDILYAT 249
+D AEL Q L + E LEKERDFYFGKLR+IE+ICQE+ E+D ++ I+DILYAT
Sbjct: 446 EDLRAELRQ----LTVEKEGLEKERDFYFGKLRDIEVICQEH--EDDVSMKAIMDILYAT 285
Query: 250 DEGF 253
++GF
Sbjct: 284 EDGF 273
>28710
Length = 525
Score = 65.5 bits (158), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 32/59 (54%), Positives = 45/59 (76%)
Frame = -1
Query: 195 ELMQQVNVLKLTVEDLEKERDFYFGKLRNIELICQENEGENDPVLQRIVDILYATDEGF 253
+L ++ + L E LEKERDFYFGKLR+IE+ICQE+ E+ ++ I+DILYAT++GF
Sbjct: 507 DLRAELRQMNLEKEGLEKERDFYFGKLRDIEIICQEH--EDSDTMKGILDILYATEDGF 337
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000328213 | hsapiens_gene_ensembl | Proto-oncogene
tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK) (Lymphocyte
cell-specific protein-tyrosine kinase) (LSK) (T cell- specific
protein-tyrosine kinase). [Source:Uniprot/SWISSPROT;Acc:P06239]
(526 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
06405 285 3e-77
21808 268 2e-72
11780 190 3e-68
04852 156 2e-38
09007 148 5e-36
07291 139 4e-33
17300 122 4e-31
07940 127 8e-30
20640 124 7e-29
14116 108 4e-24
18996 108 8e-24
17637 105 5e-23
22005 82 2e-22
08294 98 9e-21
13305 84 1e-16
01718 83 2e-16
14477 80 3e-15
19301 74 1e-13
07833 68 8e-12
29581 67 1e-11
00715 67 2e-11
01060 66 4e-11
13592 64 1e-10
18921 63 2e-10
18484 63 3e-10
14126 63 3e-10
12672 63 3e-10
12721 63 3e-10
25550 60 2e-09
01707 60 2e-09
01756 60 3e-09
17253 59 6e-09
00300 58 8e-09
14420 56 4e-08
19094 55 6e-08
01966 55 7e-08
04591 53 3e-07
30755 51 1e-06
21079 50 2e-06
15910 50 3e-06
04138 49 4e-06
13212 49 4e-06
31885 49 5e-06
27546 48 8e-06
07836 47 2e-05
26711 47 2e-05
35671 47 3e-05
01392 45 6e-05
19761 45 8e-05
26560 44 1e-04
09606 44 1e-04
13066 42 6e-04
11185 42 6e-04
21433 42 6e-04
17975 42 7e-04
03240 42 7e-04
12786 40 0.002
18481 40 0.002
28638 40 0.003
17286 40 0.003
29243 40 0.003
32264 39 0.004
16708 39 0.004
27405 38 0.009
27287 37 0.018
21210 37 0.023
32000 36 0.030
37602 36 0.032
07933 36 0.049
38046 35 0.11
20559 34 0.12
29590 34 0.18
11228 33 0.29
37260 33 0.33
15741 32 0.55
13664 32 0.69
36481 32 0.87
06462 31 1.2
20131 31 1.4
32357 31 1.5
17516 29 4.1
25100 29 5.8
18050 28 6.6
>06405
Length = 1965
Score = 285 bits (729), Expect = 3e-77, Method: Compositional matrix adjust.
Identities = 162/382 (42%), Positives = 229/382 (59%), Gaps = 8/382 (2%)
Frame = +1
Query: 142 ESESTAGSFSLSVRDFDQNQGEVVKHYKIRNLDNGGFYISPRITFPGLHELVRHYTNASD 201
ESES+ G S+SVR F+ V HY+I D+G +++ F L ELV H++ +D
Sbjct: 1 ESESSPGQRSISVR-FEGR----VYHYRITE-DDGKVFVTQEHRFNTLAELVHHHSIHAD 162
Query: 202 GLCTRLSRPCQTQKPQKPWW------EDEWEVPRETLKLVERLGAGQFGEVWMGYYNGHT 255
GL T L P K QKP D WE+ R + + RLG GQ+G+V+ + +
Sbjct: 163 GLVTTLLYPAP--KRQKPTVFGVSPEPDRWEIERTEIAMKHRLGGGQYGDVYEAMWKRYN 336
Query: 256 K-VAVKSLKQGSMSPDAFLAEANLMKQLQHQRLVRLYAVVTQE-PIYIITEYMENDTLLD 313
K VAVK+LK+ +M+ + FL EA +MK+++H LV+L V T+E P YI+TE+M
Sbjct: 337 KIVAVKTLKEDTMALNDFLEEAAIMKEMKHPNLVQLLGVCTREPPFYIVTEFM------- 495
Query: 314 SQLEEKGLGASPWGNLGQQLLLLPTGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIE 373
P G+L+D+L++ + + L+ MA QIA GMA++E
Sbjct: 496 -----------------------PHGNLLDYLRSSTREENGPTALMYMATQIASGMAYLE 606
Query: 374 ERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGT 433
+N+IHRDL A N LV+D+ K+ADFGLARL++D+ YTA GAKFPIKWTAPE + +
Sbjct: 607 TKNFIHRDLAARNCLVADSNMVKVADFGLARLMKDDTYTAHIGAKFPIKWTAPEGLAFNR 786
Query: 434 FTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDNCPEELYQLMRLC 493
F+ +SD+W+FG+LL E+ T+G PYPG+ EV LERGYRM RP P ++Y LM C
Sbjct: 787 FSTRSDIWAFGVLLWELATYGMSPYPGVELTEVYHLLERGYRMERPPGTPADVYILMLKC 966
Query: 494 WKERPEDRPTFDYLRSVLEDFF 515
W+ P+DRPTF + +LE+ F
Sbjct: 967 WQWDPKDRPTFKEIHFLLENMF 1032
>21808
Length = 1011
Score = 268 bits (685), Expect(2) = 2e-72, Method: Compositional matrix adjust.
Identities = 138/255 (54%), Positives = 175/255 (68%), Gaps = 1/255 (0%)
Frame = +1
Query: 249 GYYNGHTKVAVKSLKQGSMSPDAFLAEANLMKQLQHQRLVRLYAVVTQ-EPIYIITEYME 307
G +N T VA+K+LK G+M P FLAEA +MK+L+H +L++LYAV TQ +PI+IITE M+
Sbjct: 4 GLWNNTTPVAIKTLKSGTMDPKDFLAEAQIMKKLRHPKLIQLYAVCTQDDPIFIITELMK 183
Query: 308 NDTLLDSQLEEKGLGASPWGNLGQQLLLLPTGSLVDFLKTPSGIKLTINKLLDMAAQIAE 367
N GSL++FL+ G L + L+D+ AQIA
Sbjct: 184 N------------------------------GSLLEFLQG-KGRVLKLPALIDIGAQIAC 270
Query: 368 GMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPE 427
GMA++E +NYIHRDL A NILVSD + KIADFGLAR+I+++EY AR GA+FPIKWTAPE
Sbjct: 271 GMAYLESQNYIHRDLAARNILVSDNNTVKIADFGLARVIKEDEYEARVGARFPIKWTAPE 450
Query: 428 AINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDNCPEELY 487
A NY FTIKSDVWSFGILLTE VT+GR+PYPGMTN EV+ +E GYRM P CP+ LY
Sbjct: 451 AANYNRFTIKSDVWSFGILLTETVTYGRVPYPGMTNAEVLHQVEHGYRMPCPPGCPKPLY 630
Query: 488 QLMRLCWKERPEDRP 502
+M CW++ +RP
Sbjct: 631 DIMLECWRKEEMERP 675
Score = 23.5 bits (49), Expect(2) = 2e-72, Method: Compositional matrix adjust.
Identities = 13/29 (44%), Positives = 17/29 (58%)
Frame = +2
Query: 495 KERPEDRPTFDYLRSVLEDFFTATEGQYQ 523
K R D PTF+ L+ LE+FFT Y+
Sbjct: 656 KRRWRD-PTFETLQWKLEEFFTMDSKDYR 739
>11780
Length = 1713
Score = 190 bits (483), Expect(2) = 3e-68, Method: Compositional matrix adjust.
Identities = 126/371 (33%), Positives = 189/371 (50%), Gaps = 10/371 (2%)
Frame = +3
Query: 69 FEKGEQLRILEQSGE--WWKAQSLTTGQEGFIPFNFVA--KANSLEPEPWFFKNLSRKDA 124
F+KG+ L I + + W+KA + G+EG IP N+V K +L PWF ++R+ A
Sbjct: 111 FQKGDLLVIRRATSDRMWYKACD-SNGREGMIPANYVQPRKVVTLHAMPWFHGKITRQQA 287
Query: 125 ERQLLAPGNTHGSFLIRESESTAGSFSLSVRDFDQNQGEVVKHYKIRNLDNGGFYISPRI 184
E +LL P G FLIRES + G ++L V + V+HY+I +N I
Sbjct: 288 E-ELLKP-REDGLFLIRESSNYPGDYTLCVCHLGK-----VEHYRILYRENQ-LTIDEEG 443
Query: 185 TFPGLHELVRHYTNASDGLCTRLSRPCQTQKPQ------KPWWEDEWEVPRETLKLVERL 238
F L ELV+HY +DGLCT+L+RP Q + + W + + L++ E +
Sbjct: 444 FFRNLDELVKHYLADADGLCTQLTRPVTKQGGNFGTVSLQEFKSGGWVIAXQDLEIGEAI 623
Query: 239 GAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPDAFLAEANLMKQLQHQRLVRLYAVVTQEP 298
G G FG+V+ G Y G VA+K LK +FL EA++M L+H LVRL VV E
Sbjct: 624 GKGDFGDVYKGMYRGQP-VAIKQLKDKDRGEQSFLQEASVMTSLRHDNLVRLIGVVLGET 800
Query: 299 IYIITEYMENDTLLDSQLEEKGLGASPWGNLGQQLLLLPTGSLVDFLKTPSGIKLTINKL 358
I+++TE+M G+LV++L++ +T
Sbjct: 801 IFLVTEFM------------------------------GKGNLVEYLRSRGRSVITKKDQ 890
Query: 359 LDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAK 418
++ A M ++E + +HRDL A N+LV D K++DFGLA+ + ++ + K
Sbjct: 891 INFATDTCAAMEYLESKRLVHRDLAARNVLVHDDGKAKVSDFGLAKFGDFSQTS----VK 1058
Query: 419 FPIKWTAPEAI 429
FPIKWTAPEA+
Sbjct: 1059FPIKWTAPEAL 1091
Score = 87.0 bits (214), Expect(2) = 3e-68, Method: Compositional matrix adjust.
Identities = 39/80 (48%), Positives = 56/80 (70%)
Frame = +1
Query: 434 FTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDNCPEELYQLMRLC 493
FT KSD+WSFGILL EI + GR+PYP + +V+ ++ERGYRM P+ CP E+Y +M+
Sbjct: 1105 FTSKSDMWSFGILLWEIYSFGRVPYPRIPLTDVVMHVERGYRMEAPEGCPPEIYSIMKQA 1284
Query: 494 WKERPEDRPTFDYLRSVLED 513
W+ P +RPTF + + L +
Sbjct: 1285 WELDPNERPTFKSVLARLNN 1344
>04852
Length = 1462
Score = 156 bits (394), Expect = 2e-38, Method: Compositional matrix adjust.
Identities = 99/261 (37%), Positives = 137/261 (52%), Gaps = 8/261 (3%)
Frame = +1
Query: 255 TKVAVKSLKQ--GSMSPDAFLAEANLMKQLQ----HQRLVRLYAVVTQE-PIYIITEYME 307
+ VAVK L+ ++ F+ E +MK ++ H +V TQ P+++I E+ +
Sbjct: 22 STVAVKMLRDIVTAVEEQDFVQELQVMKAVKKMGSHINIVNFLGCCTQGGPLWVIVEFAK 201
Query: 308 NDTLLDSQLEEKGLGASPWGNLGQQLLLLPTGSLVDFLKTPSGIKLTINKLLDMAAQIAE 367
N L D LE G + +G + + KTP G + LL A QIA
Sbjct: 202 NGNLRDF-LESCRDGINGYGKF------VSPQDPGWYTKTPGGHVIRRKNLLSYAFQIAR 360
Query: 368 GMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPE 427
GM F+ R IHRDL A N+LV++ KIADFGL+R + Y R G + P+KW APE
Sbjct: 361 GMEFLASRKCIHRDLAARNVLVTEEHVLKIADFGLSR--TGDYYKKRSGGRLPVKWMAPE 534
Query: 428 AINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQN-LERGYRMVRPDNCPEEL 486
A+ +T KSDVWSFG++L EI + G +PY + N E+ L+ YRM RP+ L
Sbjct: 535 ALFDMRYTTKSDVWSFGVVLWEIFSLGGMPYASIPNEELYSKLLDDAYRMPRPELASGNL 714
Query: 487 YQLMRLCWKERPEDRPTFDYL 507
Y +M CW RP DRP F L
Sbjct: 715 YAIMERCWLNRPSDRPEFSQL 777
>09007
Length = 1440
Score = 148 bits (373), Expect = 5e-36, Method: Compositional matrix adjust.
Identities = 90/296 (30%), Positives = 147/296 (49%), Gaps = 15/296 (5%)
Frame = -1
Query: 227 VPRETLKLVERLGAGQFGEV----WMGYYNGHTKVAVKSLKQGSMSPDA--FLAEANLMK 280
+ ++ + L + LG G FG V W +VAVK L + + D FL E +M+
Sbjct: 888 ISKDCVALSKSLGQGHFGTVRQAIWTAESGEKVQVAVKCLSKDKIHKDGQEFLKETAIMQ 709
Query: 281 QLQHQRLVRLYAVVTQE--PIYIITEYMENDTLLDSQLEEKGLGASPWGNLGQQLLLLPT 338
L H+ +VR+Y VV I ++TE L P
Sbjct: 708 MLDHENIVRVYGVVMDNGADIMLVTE------------------------------LAPM 619
Query: 339 GSLVDFLKTPSG-IKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKI 397
SL++ +K S + ++ +L D + Q+ +GM+++E + +HRDL A NIL+ KI
Sbjct: 618 RSLLECVKEVSARVDFSVPRLCDFSQQVCDGMSYLESKRLVHRDLAARNILLFSKSKVKI 439
Query: 398 ADFGLA-RLIEDNEYTAREGA---KFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTH 453
+D G++ L EY + + + W APE+ F+ SDVW+FG+LL E TH
Sbjct: 438 SDVGVSGALGAGKEYYQSQQTIHLQNAVAWCAPESFRNLCFSSASDVWAFGVLLWEFFTH 259
Query: 454 GRIPYPGMTNPEVIQNLE--RGYRMVRPDNCPEELYQLMRLCWKERPEDRPTFDYL 507
G P+ G+ ++++ ++ + R+ +PD CP+E Y +M CW++ P+ RPTF L
Sbjct: 258 GFQPWAGLNGQQIMEAVDAPQSQRLEQPDLCPKEYYAVMLKCWEQEPQRRPTFSQL 91
>07291
Length = 833
Score = 139 bits (349), Expect = 4e-33, Method: Compositional matrix adjust.
Identities = 67/164 (40%), Positives = 104/164 (63%), Gaps = 2/164 (1%)
Frame = +1
Query: 353 LTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLA-RLIEDNEY 411
LT+ +LLD QIA+GMA+++E +HR+L A N +V++ +++D+G+ L + Y
Sbjct: 40 LTVVQLLDFGRQIADGMAYLQEVKVVHRNLAARNCIVTEDGRLQLSDYGVTGSLFPQSYY 219
Query: 412 TAREG-AKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNL 470
TA + A+ +KW APE I+ F+ KSDVW+FG++L E++T G PYP + N ++ L
Sbjct: 220 TADDSPARDLVKWMAPETIDNFHFSSKSDVWAFGVVLWELLTRGITPYPDVENSSLLPYL 399
Query: 471 ERGYRMVRPDNCPEELYQLMRLCWKERPEDRPTFDYLRSVLEDF 514
+ G+RM +P PE +Y++M CW E PE RP F L L+ F
Sbjct: 400 KEGHRMKKPKQSPEPVYEMMTACWNESPEQRPDFAELNDQLKTF 531
>17300
Length = 480
Score = 122 bits (307), Expect(2) = 4e-31, Method: Composition-based stats.
Identities = 57/116 (49%), Positives = 82/116 (70%), Gaps = 4/116 (3%)
Frame = +1
Query: 365 IAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIE----DNEYTAREGAKFP 420
I+ GM + + Y+HRDL A NILV++ L CK+ADFGL+R IE + YT + G K P
Sbjct: 1 ISSGMGXLADMGYVHRDLAARNILVNEILVCKVADFGLSREIESDTTEGAYTTK-GGKIP 177
Query: 421 IKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRM 476
++WTAPEAI Y FT SDVWSFG+++ E++++G PY +N +VI+ +E+GYR+
Sbjct: 178 VRWTAPEAIAYRKFTSASDVWSFGVVMWEVMSYGERPYWNWSNQDVIKAVEKGYRL 345
Score = 30.8 bits (68), Expect(2) = 4e-31, Method: Composition-based stats.
Identities = 13/39 (33%), Positives = 19/39 (48%)
Frame = +2
Query: 481 NCPEELYQLMRLCWKERPEDRPTFDYLRSVLEDFFTATE 519
+CPE L+QLM W++ RP + L+ A E
Sbjct: 356 DCPEALHQLMLDAWQKERSHRPKMSMVVKTLDKLIRAPE 472
>07940
Length = 1336
Score = 127 bits (320), Expect = 8e-30, Method: Compositional matrix adjust.
Identities = 95/279 (34%), Positives = 134/279 (48%), Gaps = 41/279 (14%)
Frame = -3
Query: 224 EWEVPRETLKLVERLGAGQFGEVW----MGYY--NGHTKVAVKSLKQGSMSPDA--FLAE 275
+WE PRE L L +RLG G FG V MG + N VAVK LK+ + + + E
Sbjct: 860 KWEFPRERLVLGDRLGEGAFGLVMKGEAMGIFKDNNSVTVAVKMLKEDATDREMMDLIRE 681
Query: 276 ANLMKQL-QHQRLVRLYAVVTQE-PIYIITEYMENDTLLDSQLEEKGLGAS--------- 324
+MK + +H+ ++ L TQ +Y+I E+ + L D + G S
Sbjct: 680 MEMMKVIGKHKNIINLLGCCTQRGALYVIVEFAPHGNLRDFLKSHRPHGTSYSCIADYEQ 501
Query: 325 ----------------PWGNLGQQLLLLPTGSLVDFLKTPSGIK-----LTINKLLDMAA 363
G L +P S V F T S + LT L+ A
Sbjct: 500 PVITSSSSSFSHPNSASSSAQGTSLGFIPGTSTVSF-STGSHRQDMLKMLTPKDLISYAY 324
Query: 364 QIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTARE-GAKFPIK 422
Q+A GM ++ + IHRDL A N+LV++ KIADFGL R ++ +Y + + P+K
Sbjct: 323 QVARGMEYLASKQCIHRDLAARNVLVAEEYVLKIADFGLTRNLQQFDYYRKTTDGRLPVK 144
Query: 423 WTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGM 461
W APEA+ +T KSDVWS+G+LL EI T G PYP +
Sbjct: 143 WMAPEALFDRKYTSKSDVWSYGVLLWEIFTLGGNPYPSV 27
>20640
Length = 1492
Score = 124 bits (312), Expect = 7e-29, Method: Compositional matrix adjust.
Identities = 61/146 (41%), Positives = 84/146 (57%), Gaps = 1/146 (0%)
Frame = +1
Query: 375 RNYIHRDLRAANILVSDTLSCKIADFGLARLIED-NEYTAREGAKFPIKWTAPEAINYGT 433
R Y+HRDL N LV L KI+DFGLAR + + Y E PI+W EAI Y
Sbjct: 1 RGYVHRDLATRNCLVGHDLVVKISDFGLARSVHSVDYYRGSEHDAIPIRWMPLEAILYNK 180
Query: 434 FTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDNCPEELYQLMRLC 493
F+ +SDVWSFG++L EI PY G+T+ EV++ ++ G + P+ P +Y+LM+ C
Sbjct: 181 FSTQSDVWSFGVVLWEIFAFALQPYYGLTHEEVVRFVKEGKVLACPERTPPPMYELMKQC 360
Query: 494 WKERPEDRPTFDYLRSVLEDFFTATE 519
W RP RP+F L LE+ + E
Sbjct: 361 WHRRPATRPSFHTLHKTLENMHSKYE 438
>14116
Length = 1017
Score = 108 bits (271), Expect = 4e-24, Method: Compositional matrix adjust.
Identities = 73/243 (30%), Positives = 115/243 (47%), Gaps = 10/243 (4%)
Frame = -1
Query: 227 VPRETLKLVERLGAGQFGEVWMGYYN-----GHTKVAVKSLKQGS---MSPDAFLAEANL 278
+ RE L + E +G G FG V G+ G VAVK+L + + +FL EA +
Sbjct: 645 IDREFLTMGEEIGKGNFGCVKRGFLTLPEQKGDILVAVKTLHNNNPREIELQSFLQEALI 466
Query: 279 MKQLQHQRLVRLYAVVTQEPIYIITEYMENDTLLDSQLEEKGLGASPWGNLGQQLLLLPT 338
MK H ++ L + L++ L P+ +
Sbjct: 465 MKDFHHSNVLTLIGICLN-------------------LDDMPLVVLPF---------MKH 370
Query: 339 GSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIA 398
G L+ +++ + TI L+ IA GM ++ ++HRDL A N ++ + K+A
Sbjct: 369 GDLLTYIRDDQH-QPTIKDLIMYGVDIARGMDYLAGLKFVHRDLAARNCMLDEDFHVKVA 193
Query: 399 DFGLARLIEDNEYTAREG--AKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRI 456
DFGLAR I + EY + E AK P+KW A E++ G + K+DVWS+G++L E++T G
Sbjct: 192 DFGLARDIYEKEYYSSENKKAKLPVKWMALESLEKGNYDSKTDVWSYGVVLWELLTRGSD 13
Query: 457 PYP 459
P
Sbjct: 12 ALP 4
>18996
Length = 491
Score = 108 bits (269), Expect = 8e-24, Method: Compositional matrix adjust.
Identities = 61/140 (43%), Positives = 82/140 (58%), Gaps = 6/140 (4%)
Frame = +2
Query: 378 IHRDLRAANILVSDTLSCKIADFGLARLIE-DNEYTAREGAKFPIKWTAPEAINYGTFTI 436
IHRDL A NILV D KI+DFGLA+ D Y PIKW +PEAI F+
Sbjct: 2 IHRDLAARNILV-DRSCVKISDFGLAQFANADGYYYGISQRDIPIKWYSPEAIETCKFSS 178
Query: 437 KSDVWSFGILLTEIVTHGRIP--YPG--MTNPEVIQNLERGYRMVRPDNCPEELY-QLMR 491
SDVWS+G+ L E+ + G IP PG +T E + L +G R+ +P+ C + +Y +LMR
Sbjct: 179 YSDVWSYGVTLFEMFSRGEIPNLLPGHDLTQEEFLNRLRKGERLPKPELCSDFVYSELMR 358
Query: 492 LCWKERPEDRPTFDYLRSVL 511
CW E P+ RPTF + ++
Sbjct: 359 PCWHEMPKSRPTFHQIIQII 418
>17637
Length = 447
Score = 105 bits (262), Expect = 5e-23, Method: Compositional matrix adjust.
Identities = 50/132 (37%), Positives = 77/132 (58%), Gaps = 1/132 (0%)
Frame = +1
Query: 386 NILVSDTLSCKIADFGLARLIEDNEYTAR-EGAKFPIKWTAPEAINYGTFTIKSDVWSFG 444
N ++ D L K+ D L+R + +Y +G PIKW + EA+ + SDVWSFG
Sbjct: 1 NCVIDDQLRVKLTDSALSRDLFSGDYNCLGDGEYRPIKWLSLEALQKSHYNEGSDVWSFG 180
Query: 445 ILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDNCPEELYQLMRLCWKERPEDRPTF 504
+L+ E+ T G++PY + E+ L+ GYR+ +P NCP+EL+ +M CW P +RP+F
Sbjct: 181 VLMWEMCTLGKLPYAEIDPYEMEHYLKDGYRLAQPFNCPDELFTIMAYCWASMPAERPSF 360
Query: 505 DYLRSVLEDFFT 516
L+ L +F T
Sbjct: 361 SQLQICLSEFHT 396
>22005
Length = 873
Score = 81.6 bits (200), Expect(2) = 2e-22, Method: Compositional matrix adjust.
Identities = 67/198 (33%), Positives = 101/198 (51%), Gaps = 18/198 (9%)
Frame = +1
Query: 272 FLAEANLMKQLQHQRLVRLYAVVT-QEPIYIITEYME----NDTLLDSQLEEKGLGASPW 326
F EA+LM H +V+L V +P+ ++ E+M ND L E L S
Sbjct: 151 FEREASLMADFDHPNIVKLLGVCAIGKPMCLLFEFMSKGDLNDFLRLCSPENYNLPVSRS 330
Query: 327 GNLGQQLLLLPTGSLVDFL------------KTPSGIKLTINKLLDMAAQIAEGMAFIEE 374
NL ++ L G V+ + SG+ T ++L ++ QI+ GMA++ +
Sbjct: 331 QNL---VVDLEDGLRVEVEAEECEKDTQSEDRDCSGMLXTKDQLY-ISQQISAGMAYLAQ 498
Query: 375 RNYIHRDLRAANILVSDTLSCKIADFGLARLIED-NEYTAREGAKFPIKWTAPEAINYGT 433
++Y+HRDL A + S T I+DFGLAR + + Y E PI+W EAI Y
Sbjct: 499 KDYVHRDL-ATRTVXSRTT*S*ISDFGLARSVHSVDYYRGSEQDAIPIRWMPLEAILYSK 675
Query: 434 FTIKSDVWSFGILLTEIV 451
F+ +SDVWSFG++L EI+
Sbjct: 676 FSTQSDVWSFGVVLWEIL 729
Score = 42.0 bits (97), Expect(2) = 2e-22, Method: Compositional matrix adjust.
Identities = 16/42 (38%), Positives = 28/42 (66%)
Frame = +3
Query: 457 PYPGMTNPEVIQNLERGYRMVRPDNCPEELYQLMRLCWKERP 498
PY G+T+ EV+ ++ G + +P P ++Y+LM+ CW+ RP
Sbjct: 744 PYYGLTHEEVVNYVKAGKILEQPTKTPHQVYELMKQCWQRRP 869
>08294
Length = 1849
Score = 97.8 bits (242), Expect = 9e-21, Method: Compositional matrix adjust.
Identities = 60/215 (27%), Positives = 103/215 (47%)
Frame = +2
Query: 297 EPIYIITEYMENDTLLDSQLEEKGLGASPWGNLGQQLLLLPTGSLVDFLKTPSGIKLTIN 356
EP ++ITEY + WG+L Q LL T + + L ++
Sbjct: 926 EPHFLITEYCD------------------WGDLKQ--FLLATRNDNGRGRGTRVPALALS 1045
Query: 357 KLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREG 416
+ L M Q+A GM + + +H DL A N+L++ + K+A L+ + +EY
Sbjct: 1046 QKLGMGQQVAAGMEALSNQGLVHGDLAARNVLLTSRMQLKVARPALSGDVYASEYYPLHQ 1225
Query: 417 AKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRM 476
P++W PE + + T DVW+FG+ L E++ +PY M++ EV+++L+
Sbjct: 1226 RLVPLRWLPPEGVLEDSATTCGDVWAFGVFLWEVLQLADLPYRLMSDEEVLRSLQHSQAA 1405
Query: 477 VRPDNCPEELYQLMRLCWKERPEDRPTFDYLRSVL 511
+ + P L L++ C ++P RP F + SVL
Sbjct: 1406 LDSPDAPPALLSLLQRCTAQQPSQRPPFSEICSVL 1510
>13305
Length = 549
Score = 84.3 bits (207), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 37/89 (41%), Positives = 52/89 (58%)
Frame = +2
Query: 416 GAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYR 475
+ PI+W A E++ T+T +SDVWSFG++L EI T G PY ++ L+ GYR
Sbjct: 2 STRVPIRWMAVESLFNNTYTTQSDVWSFGVVLWEIFTLGGTPYSSTDTQQLFAFLKDGYR 181
Query: 476 MVRPDNCPEELYQLMRLCWKERPEDRPTF 504
+ RP C + Y +M CW E + RPTF
Sbjct: 182 LKRPKLCDQNTYAMMLQCWNENAQRRPTF 268
>01718
Length = 959
Score = 83.2 bits (204), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 76/282 (26%), Positives = 122/282 (43%), Gaps = 13/282 (4%)
Frame = +3
Query: 234 LVERLGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPDAFLAEANLMKQLQHQRLVRLYAV 293
+ E++GAG F EV+ + +V + + + L E L+ +LQH ++R V
Sbjct: 159 ICEKIGAGFFSEVFKVTHRITGQVMALKMNTMTSNRHNMLREVQLLNRLQHANILRFMGV 338
Query: 294 VTQE-PIYIITEYMENDTLLDSQLEEKGLGASPWGNLGQQLLLLPTGSLVDFLKTPSGIK 352
E ++ +TEY+ + L QL EK PW I+
Sbjct: 339 CVHEGQLHALTEYIPSGNL--EQLLEKKDEELPW---------------------TQRIQ 449
Query: 353 LTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILV----SDTLSCKIADFGLARLIE- 407
LT+ +A G+ ++ +IHRDL + NIL+ + IADFGLA I
Sbjct: 450 LTLG--------LARGLDYLHSTRFIHRDLTSKNILIRREDNHGYHAVIADFGLATKIPD 605
Query: 408 --DNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPE 465
D E G+ + W APE +N + ++D++S GI++ EI RIP +P+
Sbjct: 606 PLDKEKLPTVGSPY---WMAPEVLNGHFYNERADLFSVGIIMCEIT--ARIP----ADPD 758
Query: 466 V---IQNLERGYRMVRP--DNCPEELYQLMRLCWKERPEDRP 502
+ + N Y + CP + QL C + P+ RP
Sbjct: 759 IMPRMNNFGVDYVALSEMISYCPLDYLQLAFKCCQVDPQKRP 884
>14477
Length = 493
Score = 79.7 bits (195), Expect = 3e-15, Method: Composition-based stats.
Identities = 55/188 (29%), Positives = 87/188 (46%), Gaps = 8/188 (4%)
Frame = -1
Query: 237 RLGAGQFGEVWMGYY---NGHTKVAVKSLKQGSMSPDA---FLAEANLMKQLQHQRLVRL 290
+LGAG FG V G + VA+K LK + P + EA +MK++ H +VRL
Sbjct: 469 KLGAGNFGSVMKGVCRLDDREIPVAIKVLKNADLDPSVQSELIKEAEVMKKMDHMHIVRL 290
Query: 291 YAVVTQEPIYIITEYMENDTLLDSQLEEKGLGASPWGNLGQQLLLLPTGSLVDFLKTPSG 350
+ E + ++ E L G L FL P
Sbjct: 289 IGLCEGETMMLVLE------------------------------LAKLGPLNKFL--PKN 206
Query: 351 IKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLI--ED 408
L + +L++ Q+++GM ++E ++HRDL A NIL+ D KI+DFG+++ + E+
Sbjct: 205 KHLPLWNILELMWQVSQGMEYLEANKFVHRDLAARNILLCDEHFAKISDFGMSKTLSREN 26
Query: 409 NEYTAREG 416
N Y A+E
Sbjct: 25 NYYMAQEA 2
>19301
Length = 712
Score = 73.9 bits (180), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 53/183 (28%), Positives = 85/183 (46%), Gaps = 1/183 (0%)
Frame = +2
Query: 222 EDEWEVPRETLKLVERLGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPDAFLAEANLMKQ 281
+D+WE+P E++ +E LG+G G V++G +VAVK ++ D + +++
Sbjct: 281 QDDWEIPFESITDLEWLGSGAQGAVFLGKLCAE-EVAVKKVR------DIKETDIRNLRK 439
Query: 282 LQHQRLVRLYAVVTQEPIY-IITEYMENDTLLDSQLEEKGLGASPWGNLGQQLLLLPTGS 340
L H ++ V TQ P Y II EY P G
Sbjct: 440 LNHPNIISFKGVCTQAPCYCIIMEY------------------------------CPYGQ 529
Query: 341 LVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADF 400
L + L+ G ++ +LD + QIA GM ++ IHRDL++ N+LV+ KI+DF
Sbjct: 530 LYEVLR--DGKEIPPALVLDWSKQIASGMNYLHSHKIIHRDLKSPNVLVAKNDVVKISDF 703
Query: 401 GLA 403
G +
Sbjct: 704 GTS 712
>07833
Length = 1504
Score = 68.2 bits (165), Expect = 8e-12, Method: Compositional matrix adjust.
Identities = 53/186 (28%), Positives = 91/186 (48%), Gaps = 8/186 (4%)
Frame = -3
Query: 335 LLPTGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIE--ERNYIHRDLRAANILVSDT 392
+P GSL + L SGI + N+ L A IA GM F+ E + L + ++++ +
Sbjct: 1376 FMPFGSLYNTLHGESGIVVDQNQSLRFAMDIARGMEFLHSMEPTIPNFLLTSKHVMIDED 1197
Query: 393 LSCKI--ADFGLARLIEDNEYTAREGAKFPIKWTAPEAINY---GTFTIKSDVWSFGILL 447
L+ +I AD+ + +G + W APEA+ T +D+WSF IL+
Sbjct: 1196 LTARINMADYCFS--------FHEKGKVYSPAWMAPEALQRRPDDINTRAADMWSFAILM 1041
Query: 448 TEIVTHGRIPYPGMTNPEV-IQNLERGYRMVRPDNCPEELYQLMRLCWKERPEDRPTFDY 506
E+ T +P+ +++ EV ++ G R+ P + +L+++C E P RP FD
Sbjct: 1040 WELETR-EVPFAELSSMEVGMKVALEGLRISIPPGISLHMSRLIKICMNEEPGKRPRFDM 864
Query: 507 LRSVLE 512
+ +LE
Sbjct: 863 IIPILE 846
>29581
Length = 1278
Score = 67.4 bits (163), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 54/215 (25%), Positives = 99/215 (46%), Gaps = 8/215 (3%)
Frame = -2
Query: 262 LKQGSMSPDAFLAEANLMKQLQHQRLVRLYAVV---TQEPIYIITEYMENDTLLDSQLEE 318
L++ +SP + + L+HQ +V+L VV + + ++++ EY E D
Sbjct: 1244 LERDMVSPSVVCVRSTFLLNLRHQNIVQLQEVVVGKSLDSLFLVMEYCEQDL-------- 1089
Query: 319 KGLGASPWGNLGQQLLLLPTGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYI 378
SL+D + P + +++ + Q+ +G+ ++ E I
Sbjct: 1088 --------------------ASLLDNMPAP----FSESQVKCIVLQLLKGLRYLHEAFII 981
Query: 379 HRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFP----IKWTAPEAI-NYGT 433
HRDL+ +N+L++D KIADFGLAR Y + P + + APE + T
Sbjct: 980 HRDLKVSNLLMTDKGCVKIADFGLAR-----NYGKPQKPMTPKVVTLWYRAPELLFGSKT 816
Query: 434 FTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQ 468
+ D+WS G +L E++ H + PG ++ + I+
Sbjct: 815 HSTAIDMWSAGCILGELLGHKPL-MPGRSDLQQIE 714
>00715
Length = 1788
Score = 67.0 bits (162), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 49/172 (28%), Positives = 82/172 (47%), Gaps = 27/172 (15%)
Frame = +1
Query: 359 LDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLI------------ 406
L +A Q+A G+ ++ N +H DL+ AN L++ L +IADFG +
Sbjct: 247 LSLALQMARGLHYLHSINIVHLDLKPANCLLTRDLKLRIADFGCCHQLTPTGLDMGEREG 426
Query: 407 ----EDNEYTAREGA-----KFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIP 457
+ E T +GA + + APE + +++SDV+S GI L ++ T + P
Sbjct: 427 GMAGNELELTPVQGAWKNELAGTLAYRAPELLKGLQPSVRSDVYSLGITLWQMCTR-QGP 603
Query: 458 YPGMTNPEVI-QNLERGYRMVRPDNCPEELYQLM-----RLCWKERPEDRPT 503
Y G+ V+ Q + + R P + ++ +++M CW R EDRPT
Sbjct: 604 YEGVPAHAVVYQVVSKDLRPCPPPSTEDDPFEVMFRDLYTQCWARRVEDRPT 759
>01060
Length = 1800
Score = 65.9 bits (159), Expect = 4e-11, Method: Compositional matrix adjust.
Identities = 60/260 (23%), Positives = 115/260 (44%), Gaps = 6/260 (2%)
Frame = +1
Query: 224 EWEVPRETLKLVERLGAGQFGEVWMGYYNGH-TKVAVKSLK-QGSMS--PDAFLAEANLM 279
++E L +++G G +G V+ + K+A+K ++ +GS P + + E ++
Sbjct: 55 DFETALSDLTDFQKIGEGTYGVVYKCRHRATGRKLAMKKIRLRGSEDGVPSSAIREIAML 234
Query: 280 KQLQHQRLVRLYAVVTQ-EPIYIITEYMENDTLLDSQLEEKGLGASPWGNLGQQLLLLPT 338
++L+H +V L V+ + E ++++ E++ D +
Sbjct: 235 RELRHTNIVCLEDVIMEDERLFLVFEFLSMDLKM-------------------------- 336
Query: 339 GSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIA 398
+D K P G+ L + QI G+ F +R +HRDL+ N+L++ T + KIA
Sbjct: 337 --YID--KFPEGVVLDRRLVKSYVFQIVTGIXFCHQRRIVHRDLKPQNLLINHTGAIKIA 504
Query: 399 DFGLARLIEDNEYTAREGAKFPIKWTAPEAI-NYGTFTIKSDVWSFGILLTEIVTHGRIP 457
DFG+AR A + + APE + ++ DVWS G + +++ I
Sbjct: 505 DFGMARTFA-LPVRAYTHEVVTLWYRAPEILMGASKYSTPVDVWSIGTIFADML----IR 669
Query: 458 YPGMTNPEVIQNLERGYRMV 477
P I L + +R++
Sbjct: 670 TPIFKGDSEIDQLFKIFRII 729
>13592
Length = 980
Score = 63.9 bits (154), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 61/282 (21%), Positives = 124/282 (43%), Gaps = 17/282 (6%)
Frame = +2
Query: 237 RLGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPDAFLAEANLMKQLQ------HQRLVRL 290
++G G+FG+V+ N ++ ++K+ ++ P A N+ ++L+ H+ LVR
Sbjct: 5 KIGQGRFGKVYTAVNNNTGELM--AMKEIAIQPGETRALKNVAEELKILEGIKHKNLVRY 178
Query: 291 YAV-VTQEPIYIITEYMENDTLLDSQLEEKGLGASPWGNLGQQLLLLPTGSLVDFLKTPS 349
Y + V +E + I E L G+L ++
Sbjct: 179 YGIEVHREELLIFME------------------------------LCSEGTLESLVELTG 268
Query: 350 GIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANI-LVSDTLSCKIADFGLARLIED 408
G+ +++ AQ+ G+A + + +HRD++ ANI LV + S K+ DFG A I+
Sbjct: 269 GLPEALSR--RFTAQLLSGVAELHKHGIVHRDIKTANIFLVDGSNSLKLGDFGSAVKIQA 442
Query: 409 NE--------YTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPG 460
+ Y + P +T + +G +D+WS G ++ E+ + G+ P+
Sbjct: 443 HTTVPGELQGYVGTQAYMAPEVFTKTNSDGHGRL---ADIWSVGCVVVEMAS-GKRPWAQ 610
Query: 461 M-TNPEVIQNLERGYRMVRPDNCPEELYQLMRLCWKERPEDR 501
+N +++ + G + P++ +E + + C + P+ R
Sbjct: 611 FDSNFQIMFKVGMGEKPQAPESLSQEGHDFIDHCLQHDPKQR 736
>18921
Length = 697
Score = 63.2 bits (152), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 53/226 (23%), Positives = 98/226 (43%), Gaps = 3/226 (1%)
Frame = +2
Query: 228 PRETLKLVERLGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPDA--FLAEANLMKQLQHQ 285
P + ++ +LG G +G V+ + +V ++KQ + D + E ++M+Q +
Sbjct: 23 PEDVFDILGKLGEGSYGSVFKSLHKETGQVL--AIKQVPVDTDLQEIIKEISIMQQCDSK 196
Query: 286 RLVRLY-AVVTQEPIYIITEYMENDTLLDSQLEEKGLGASPWGNLGQQLLLLPTGSLVDF 344
+V+ Y + ++I+ EY GA GS+ D
Sbjct: 197 YIVKYYGSYFKNTDLWIVMEY---------------CGA---------------GSVSDI 286
Query: 345 LKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLAR 404
++ + L ++ + +G+ ++ R IHRD++A NIL+++ K+ADFG+A
Sbjct: 287 MRLRNK-TLVEREIATILYYTLKGLXYLHSRRKIHRDIKAGNILLNNEGHAKLADFGVAG 463
Query: 405 LIEDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEI 450
+ D P W APE I + +D+WS GI E+
Sbjct: 464 QLTDTMAKRNTVIGTPY-WMAPEVIQEIGYDCVADIWSLGITALEM 598
>18484
Length = 635
Score = 63.2 bits (152), Expect = 3e-10, Method: Compositional matrix adjust.
Identities = 39/140 (27%), Positives = 70/140 (50%)
Frame = +1
Query: 362 AAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPI 421
AA+IA G+ F+ ++ I+RDL+ N+++ KIADFG+ + + T R P
Sbjct: 61 AAEIAVGLFFLHDQGIIYRDLKLDNVMLDSEGHIKIADFGMCKEGMTGDATTRTFCGTP- 237
Query: 422 KWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDN 481
+ APE + Y ++ D W++G+LL E++ G+ P+ G E+ ++ + + P
Sbjct: 238 DYIAPEIVLYQPYSKSVDWWAYGVLLFEMLA-GQPPFDGEDEDELFSSI-TDHNVSYPKA 411
Query: 482 CPEELYQLMRLCWKERPEDR 501
E L + + P R
Sbjct: 412 MSREAVSLCKGLLMKNPTKR 471
>14126
Length = 1265
Score = 63.2 bits (152), Expect = 3e-10, Method: Compositional matrix adjust.
Identities = 60/232 (25%), Positives = 98/232 (42%), Gaps = 14/232 (6%)
Frame = +3
Query: 235 VERLGAGQFGEVWMG--YYNGHTKVAVKSLKQGSMS---PDAFLAEANLMKQLQ---HQR 286
V +G G +G V+ N VA+K ++ + P + E +++KQL+ H
Sbjct: 204 VAVIGNGAYGTVYKARDLRNQGEFVAMKRIRLNNTEEGMPMMAIREISMLKQLEQYEHPN 383
Query: 287 LVRLYAV----VTQEPIYI--ITEYMENDTLLDSQLEEKGLGASPWGNLGQQLLLLPTGS 340
+VRL V +T I + + EY+E+D L P LG
Sbjct: 384 VVRLLDVSHNTITDREIRLNLVFEYIEHDL-------ATYLAKCPSPGLG---------- 512
Query: 341 LVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADF 400
P IK D+ Q+ G+ F+ +HRDL+ N+L+S K+ADF
Sbjct: 513 -------PDRIK-------DLMLQLLNGVDFLHSNRIVHRDLKPQNLLISKDGRLKLADF 650
Query: 401 GLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVT 452
GLAR+ + + A + + +PE + + D+WS G + E+ T
Sbjct: 651 GLARIY--SFHMALTTVVVTLWYRSPEVLMQAEYGTSVDIWSCGCIFAELFT 800
>12672
Length = 773
Score = 63.2 bits (152), Expect = 3e-10, Method: Compositional matrix adjust.
Identities = 43/166 (25%), Positives = 72/166 (43%), Gaps = 17/166 (10%)
Frame = +3
Query: 366 AEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPI---K 422
A G+ ++ + ++HRD++ ANIL+ + K+ DF E + A I
Sbjct: 21 ASGIQYLNDNGHVHRDIKTANILLDSEYTAKVGDFATVVSAPSGEGKTVQNASVVIGTAA 200
Query: 423 WTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIP--------------YPGMTNPEVIQ 468
+ APEAI++ T K D +SFG++L E++T G + + PE I
Sbjct: 201 YLAPEAIHFDVST-KLDSYSFGVVLLEVIT-GLVAQDYSREERTLSSHIMENVEEPEEIH 374
Query: 469 NLERGYRMVRPDNCPEELYQLMRLCWKERPEDRPTFDYLRSVLEDF 514
+ PD ++LY + C + RP +R LE+
Sbjct: 375 DFVDQSAGTWPDGAVDKLYDISMRCLNLSKKQRPNVKDIRPELEEL 512
>12721
Length = 821
Score = 63.2 bits (152), Expect = 3e-10, Method: Compositional matrix adjust.
Identities = 48/226 (21%), Positives = 94/226 (41%), Gaps = 2/226 (0%)
Frame = +1
Query: 228 PRETLKLVERLGAGQFGEVWMGYYNGHTKVAVKSLK-QGSMSPDAFLAEANLMKQLQHQR 286
PR L ++G G G V + ++AVK + + + E +M+ H
Sbjct: 82 PRTFLDDFMKIGEGSTGIVCIATSRDGRQMAVKKMDLRKQQRRELLFNEVVVMRDYHHPN 261
Query: 287 LVRLY-AVVTQEPIYIITEYMENDTLLDSQLEEKGLGASPWGNLGQQLLLLPTGSLVDFL 345
+V +Y + + + ++++ E+ME L D + T + +D +
Sbjct: 262 IVEMYNSYLVNDELWVVMEFMEGGALTD----------------------IVTNNRMDEV 375
Query: 346 KTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARL 405
+ + + + L AF+ IHRD+++ +IL+S K+ DFG
Sbjct: 376 QIATVCRACLKAL-----------AFLHANGVIHRDIKSDSILLSHDGKVKLXDFGFCAQ 522
Query: 406 IEDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIV 451
+ + + P W APE I+ + + D+WS GI++ E++
Sbjct: 523 VTQDLQKRKSLVGTPY-WMAPEVISRLPYGPEVDIWSLGIMVMEMI 657
>25550
Length = 941
Score = 60.5 bits (145), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 28/63 (44%), Positives = 39/63 (61%)
Frame = +3
Query: 456 IPYPGMTNPEVIQNLERGYRMVRPDNCPEELYQLMRLCWKERPEDRPTFDYLRSVLEDFF 515
+ YPG+ EV LERGYRM RP P ++Y LM CW+ P++RPTF + +LE+ F
Sbjct: 36 VXYPGVDLTEVYHLLERGYRMERPQGTPADVYILMLKCWQWDPKERPTFKEIHYLLENMF 215
Query: 516 TAT 518
+
Sbjct: 216 EKS 224
>01707
Length = 757
Score = 60.5 bits (145), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 61/242 (25%), Positives = 111/242 (45%), Gaps = 8/242 (3%)
Frame = +1
Query: 230 ETLKLVERLGAGQFGEVWMGYYNGHTK-VAVKSLKQGSMSP---DAFLAEANLMKQLQHQ 285
E + + ++G G +G V+ ++ VA+K + P + E ++KQL+H
Sbjct: 64 EKYEKIGKIGEGSYGVVFKCRNKETSQLVAIKKFVESEDDPLIKKIAMREIRMLKQLKHP 243
Query: 286 RLVRLYAVVTQEP-IYIITEYMENDTLLDSQLEEKGLGASPWGNLGQQLLLLPTGSLVDF 344
LVRL V ++ ++++ +Y+++ TLL+ L P G
Sbjct: 244 NLVRLIEVFRRKKRLHLVFDYVDH-TLLNE------LDRYPRG----------------- 351
Query: 345 LKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLAR 404
L P ++ LL + F + N IHRD++ NIL++ K+ DFG AR
Sbjct: 352 LPEPMVKRIIYQTLL--------AVNFCHQYNTIHRDVKPENILITRQGQVKLCDFGFAR 507
Query: 405 LIE--DNEYTAREGAKFPIKWTAPEAINYGT-FTIKSDVWSFGILLTEIVTHGRIPYPGM 461
++ +EYT ++ + APE + T + DVW+ G + E++T G+ +PG
Sbjct: 508 ILTGPGDEYTDYVATRW---YRAPELLVGDTQYGPPVDVWAIGCVFAELLT-GQALWPGR 675
Query: 462 TN 463
++
Sbjct: 676 SD 681
>01756
Length = 1858
Score = 59.7 bits (143), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 60/253 (23%), Positives = 101/253 (39%), Gaps = 24/253 (9%)
Frame = -3
Query: 228 PRETLKL-----------VERLGAGQFGEVWMGYYN------GHTKVAVKSLKQGSMSPD 270
P ETLK + ++G G FGEV+ KV + + K+G P
Sbjct: 1781 PYETLKFPFCDEDAKYEKLAKIGQGTFGEVFKARCKKTKQVVAMKKVLMDNEKEGF--PI 1608
Query: 271 AFLAEANLMKQLQHQRLVRLYAVVTQEPIYIITEYMENDTLLDSQLEEKGLGASPWGNLG 330
L E +++ L H+ +V L + + K A+ + ++
Sbjct: 1607 TALREIKILQLLNHENVVDLIEICST----------------------KATSANRYKSMF 1494
Query: 331 QQLLLLPTGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVS 390
+ L L S + + ++ ++ Q+ G+ +I +HRD++AANIL++
Sbjct: 1493 YLVFEFCEHDLAGLLSNMSVV-FNLPEIKEVMKQLMNGLYYIHRNKILHRDMKAANILIT 1317
Query: 391 DTLSCKIADFGLAR-----LIEDNEYTAREGAKFPIKWTAPEAINYG--TFTIKSDVWSF 443
K+ADFGLAR L + N YT R W P + G ++ D W
Sbjct: 1316 KQGVLKLADFGLARAFSVNLRQPNRYTNR----VVTLWYRPPELLLGDRNYSTAIDQWGA 1149
Query: 444 GILLTEIVTHGRI 456
G ++ E+ T I
Sbjct: 1148 GCIMAEMWTRNPI 1110
>17253
Length = 483
Score = 58.5 bits (140), Expect = 6e-09, Method: Composition-based stats.
Identities = 46/173 (26%), Positives = 78/173 (45%), Gaps = 6/173 (3%)
Frame = -1
Query: 257 VAVKSLKQGSMSPDA--FLAEANLMKQL-QHQRLVRLYAVVT-QEPIYIITEYMENDTLL 312
VAVK+ + + + FL E ++M++L +H +V T +P I+ E+ + LL
Sbjct: 459 VAVKTHNEAATDAEKSEFLRELSIMRKLPRHPNVVSFMGCCTMSDPALILMEFCCHGDLL 280
Query: 313 DSQLEEKGLGASPWGNLGQQLLLLPTGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFI 372
+ + P ++ FL T + LT A +A GMA +
Sbjct: 279 SFLRKRR-----------------PDRTV--FL-TSTANDLTARDFFSFALHVARGMAHV 160
Query: 373 EERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNE--YTAREGAKFPIKW 423
+HRD+ A N+L+S+ CK++DFGL+R + D Y P++W
Sbjct: 159 ANNKIVHRDVAARNVLISERNVCKVSDFGLSRRVGDQNDVYEIVSRRPLPLRW 1
>00300
Length = 2318
Score = 58.2 bits (139), Expect = 8e-09, Method: Compositional matrix adjust.
Identities = 61/278 (21%), Positives = 117/278 (42%), Gaps = 13/278 (4%)
Frame = -1
Query: 237 RLGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPD------AFLAEANLMKQLQHQRLVRL 290
++G GQFG+V+ + + +LK+ P+ E + + +QH+ LV+
Sbjct: 1637 KIGEGQFGKVYTAV--NMSTGELMALKEMKFQPNDLQQLREMCDEIKIFEGIQHENLVKY 1464
Query: 291 YAV-VTQEPIYIITEYMENDTLLDSQLEEKGLGASPWGNLGQQLLLLPTGSLVDFLKTPS 349
Y V V ++ + + EY + T+ + A+ G L + L+ T +V
Sbjct: 1463 YGVEVHKDEMLMFMEYCDTGTIEE---------AAKMG-LPEYLIRRYTREIV------- 1335
Query: 350 GIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDN 409
L +N L E + +HRD++ ANI ++ K+ DFG + ++ +
Sbjct: 1334 ---LAVNHL--------------HENSIVHRDIKGANIFLTSNGHVKLGDFGCSVKLKSH 1206
Query: 410 EYTAREGAKF--PIKWTAPEAI---NYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNP 464
E + APE + G + +D+WS G ++ E+ T G+ P+ + N
Sbjct: 1205 TTMPGEFHNLVGTTAYMAPEVFTQNDQGGYGRAADIWSLGCVVIEMAT-GKRPWHDLDNN 1029
Query: 465 -EVIQNLERGYRMVRPDNCPEELYQLMRLCWKERPEDR 501
+++ + G++ PD+ E + L P R
Sbjct: 1028 YQIMYKVGIGHKPAVPDSLSVEGKHFLDLIMCHDPAQR 915
>14420
Length = 528
Score = 55.8 bits (133), Expect = 4e-08, Method: Compositional matrix adjust.
Identities = 33/126 (26%), Positives = 59/126 (46%), Gaps = 2/126 (1%)
Frame = +2
Query: 335 LLPTGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLS 394
L GSL D + + ++ + + + + F+ E IHRD+++ NIL+ S
Sbjct: 143 FLAGGSLTDVVTETC---MDEGQIAAVCRECLQALEFLHENQVIHRDIKSDNILLGMDGS 313
Query: 395 CKIADFGLARLI--EDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVT 452
K+ DFG + E ++ + G + W APE + + D+WS G++ E++
Sbjct: 314 VKLTDFGFCAQLSPEQSKRSTMVGTPY---WMAPEVVTRKQYGPTVDIWSLGVMCIEMI- 481
Query: 453 HGRIPY 458
G PY
Sbjct: 482 EGEPPY 499
>19094
Length = 898
Score = 55.5 bits (132), Expect = 6e-08, Method: Compositional matrix adjust.
Identities = 29/84 (34%), Positives = 45/84 (53%)
Frame = +1
Query: 367 EGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAP 426
+G+ ++ R IHRD++A NIL+++ K+ADFG+A + D P W AP
Sbjct: 91 KGL*YLHSRRKIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTP-YWMAP 267
Query: 427 EAINYGTFTIKSDVWSFGILLTEI 450
E I + +D+WS GI E+
Sbjct: 268 EVIQEIGYDCVADIWSLGITALEM 339
>01966
Length = 1735
Score = 55.1 bits (131), Expect = 7e-08, Method: Compositional matrix adjust.
Identities = 40/153 (26%), Positives = 74/153 (48%), Gaps = 4/153 (2%)
Frame = -1
Query: 256 KVAVKSLK-QGSMS--PDAFLAEANLMKQLQHQRLVRLYAVVTQ-EPIYIITEYMENDTL 311
K+A+K ++ +GS P + + E ++++L+H +V L V+ + E ++++ E++ D
Sbjct: 1630 KLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTNIVCLEDVIMEDERLFLVFEFLSMDLK 1451
Query: 312 LDSQLEEKGLGASPWGNLGQQLLLLPTGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAF 371
+ +D K P G+ L + QI G+ F
Sbjct: 1450 M----------------------------YID--KFPEGVVLDRRLVKSYVFQIVTGINF 1361
Query: 372 IEERNYIHRDLRAANILVSDTLSCKIADFGLAR 404
+R +HRDL+ N+L++ T + KIADFG+AR
Sbjct: 1360 CHQRRIVHRDLKPQNLLINHTGAIKIADFGMAR 1262
>04591
Length = 1117
Score = 52.8 bits (125), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 43/194 (22%), Positives = 83/194 (42%), Gaps = 12/194 (6%)
Frame = -2
Query: 269 PDAFLAEANLMKQLQHQRLVRLYAVVTQEP---------IYIITEYMENDTLLDSQLEEK 319
P L E +++QL+H+ +V+L + + Y+I EY + D
Sbjct: 1089 PITALREIKILQQLEHENVVQLQEICHTQAGPYNRYKSTFYLIFEYCDYDL--------- 937
Query: 320 GLGASPWGNLGQQLLLLPTGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIH 379
L++ L+ +K ++ ++ +Q+ G+ +I + +H
Sbjct: 936 -------------------AGLLNNLR----VKFSLADKKNLMSQLLNGLFYIHTKQILH 826
Query: 380 RDLRAANILVSDTLSCKIADFGLAR-LIEDNEYTAREGAKFPIKWTAPEAINYG--TFTI 436
RD++AANIL++ K+ADFGL+R ++ T R W P + G +
Sbjct: 825 RDIKAANILLTRDGVLKLADFGLSRPWVKSKRLTNR----VVTLWYRPPELLLGEREYGP 658
Query: 437 KSDVWSFGILLTEI 450
+ D+W G ++ E+
Sbjct: 657 EIDMWGVGCIMAEM 616
>30755
Length = 1137
Score = 50.8 bits (120), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 37/142 (26%), Positives = 69/142 (48%), Gaps = 2/142 (1%)
Frame = +2
Query: 362 AAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEY--TAREGAKF 419
A+I + ++ + I+RDL+ N+L+ K+ADFGL + ED Y T +
Sbjct: 50 GAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCK--EDITYGRTTKTFCGT 223
Query: 420 PIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRP 479
P ++ APE ++ + D W G+++ E++ GR+P+ + +V+ L + P
Sbjct: 224 P-EYLAPEVLDDNDYGRAVDWWGTGVVMYEMIC-GRLPFYNRDH-DVLFTLILVEDVKFP 394
Query: 480 DNCPEELYQLMRLCWKERPEDR 501
N +E L+ + P +R
Sbjct: 395 RNITDEAKSLLSGLLAKDPRNR 460
>21079
Length = 878
Score = 50.1 bits (118), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 31/97 (31%), Positives = 50/97 (51%), Gaps = 3/97 (3%)
Frame = +1
Query: 353 LTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANIL-VSDTLS-CKIADFGLARLIE-DN 409
LT + QI G+ ++ ++ +H DL+ N+L VSD + KI DFGLAR + +
Sbjct: 118 LTERDCVHFVRQICSGVGYMHTQSILHLDLKPENVLCVSDNSNQIKIIDFGLARFYKPGD 297
Query: 410 EYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGIL 446
G ++ APE +NY +D+WS G++
Sbjct: 298 SLQVLFGTP---EFIAPEVVNYDEINFTTDMWSIGVI 399
>15910
Length = 1361
Score = 49.7 bits (117), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 34/114 (29%), Positives = 57/114 (50%), Gaps = 3/114 (2%)
Frame = +2
Query: 363 AQIAEGMAFIEERNYIHRDLRAANIL---VSDTLSCKIADFGLARLIEDNEYTAREGAKF 419
+ I G+ +I +HRDL+ N+L ++D K+ADFGL+R+IE E
Sbjct: 485 SDILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLADFGLSRIIEP-EVQMSTVCGT 661
Query: 420 PIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERG 473
P + APE + +T D+WS G+ + I+ G P+ E+ + + +G
Sbjct: 662 P-GYCAPEVLKGDKYTPSVDMWSVGV-IAYILLCGYEPFFAENEFEMYRKIIKG 817
>04138
Length = 800
Score = 49.3 bits (116), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 32/97 (32%), Positives = 47/97 (48%), Gaps = 7/97 (7%)
Frame = +1
Query: 367 EGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLAR-----LIEDNEYTAREGAKFPI 421
E + +I +HRD++AANIL++ K+ADFGLAR L + N YT R
Sbjct: 46 ERLYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNR----VVT 213
Query: 422 KWTAPEAINYG--TFTIKSDVWSFGILLTEIVTHGRI 456
W P + G ++ D W G ++ E+ T I
Sbjct: 214 LWYRPPELLLGDRNYSTAIDQWGAGCIMAEMWTRNPI 324
>13212
Length = 1067
Score = 49.3 bits (116), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 29/94 (30%), Positives = 49/94 (52%), Gaps = 8/94 (8%)
Frame = -1
Query: 364 QIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKF---P 420
++ + F+ + IHRD++A N+L++ K+ADFG++ N T ++ F P
Sbjct: 956 EMCMALDFLHRHHVIHRDIKAGNVLLTIDGEVKLADFGVSA---KNTQTQQKRDTFIGTP 786
Query: 421 IKWTAPEAINYGT-----FTIKSDVWSFGILLTE 449
W APE + T + K+D+WS G+ L E
Sbjct: 785 Y-WMAPEVVLCETLKDTPYDFKADIWSLGVTLIE 687
>31885
Length = 529
Score = 48.9 bits (115), Expect = 5e-06, Method: Compositional matrix adjust.
Identities = 30/111 (27%), Positives = 52/111 (46%), Gaps = 7/111 (6%)
Frame = -2
Query: 363 AQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIK 422
Q+A + ++ + +HRD++ NIL+ + C + DF +A +ED+E P
Sbjct: 351 CQLALVLDYLRSQKIVHRDIKPDNILLDEQGHCHVTDFNIATQLEDDELATSTSGTRP-- 178
Query: 423 WTAPEAINYGT-------FTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEV 466
+ APE YG + D WS G+ L E++ R P+ +N +
Sbjct: 177 YMAPEV--YGVAINERRGYGFPVDWWSLGVSLFELLKKRR-PFSVHSNTSL 34
>27546
Length = 426
Score = 48.1 bits (113), Expect = 8e-06, Method: Composition-based stats.
Identities = 33/138 (23%), Positives = 61/138 (44%), Gaps = 1/138 (0%)
Frame = -1
Query: 272 FLAEANLMKQLQHQRLVRLYAVVTQEP-IYIITEYMENDTLLDSQLEEKGLGASPWGNLG 330
F E ++ +L H ++++++++ + P I+I Y E +L S +++ G P
Sbjct: 339 FPRELEILTRLDHPNIIQIHSILQRGPKIFIFMRYAEKGDML-SHIKKTG----PIDEAQ 175
Query: 331 QQLLLLPTGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVS 390
++ Q+A+ + ++ + HRDL+ NIL+S
Sbjct: 174 TKVWFF---------------------------QMAKALQYLHSHDIAHRDLKCENILLS 76
Query: 391 DTLSCKIADFGLARLIED 408
L+ KIADFG AR D
Sbjct: 75 KRLNVKIADFGFARYCRD 22
>07836
Length = 1478
Score = 47.0 bits (110), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 59/227 (25%), Positives = 99/227 (43%), Gaps = 45/227 (19%)
Frame = -1
Query: 322 GASPWGNLGQQLLLLPTGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNY---- 377
G W L GSL D+L + L +++L +A G+A + +
Sbjct: 1349 GTGSWTQLFLITDYHENGSLHDYLLSRV---LDSSEMLALAHSAICGLAHLHIEIFGTRG 1179
Query: 378 ----IHRDLRAANILVSDTLSCKIADFGLA-RLI-EDNEYTA----REGAKFPIKWTAPE 427
HRD+++ NILV +C IAD GLA R I E NE R+G K ++ APE
Sbjct: 1178 KPAIAHRDIKSKNILVKKNGTCCIADLGLAVRYISESNEVDVAPNPRQGTK---RYMAPE 1008
Query: 428 AI-------NYGTFTIKSDVWSFGILLTEI----VTHG-----RIPY-------PGMTNP 464
+ N+ F ++D+++FG+++ EI V G ++P+ P +
Sbjct: 1007 VLEMLLNVKNFDAFK-QADMYAFGLVMWEIARCCVIGGVAEEYQVPFYNCLPHDPSFEDV 831
Query: 465 EVIQNLERGYRMVRPDN--------CPEELYQLMRLCWKERPEDRPT 503
++ ++++ VRPD + + ++M CW P R T
Sbjct: 830 RLVVSVDK----VRPDIPLRWQEDPIMKVMVKVMCECWSGNPAARLT 702
>26711
Length = 405
Score = 47.0 bits (110), Expect = 2e-05, Method: Composition-based stats.
Identities = 33/111 (29%), Positives = 58/111 (52%), Gaps = 3/111 (2%)
Frame = -2
Query: 364 QIAEGMAFIEERNYIHRDLRAANILVS-DTL-SCKIADFGLAR-LIEDNEYTAREGAKFP 420
Q+ + + + + +H DL+ +N+L+S D L S ++ DFGLAR L E G
Sbjct: 392 QVLDILQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARKLYPPQETFLNHGTP-- 219
Query: 421 IKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLE 471
+T+PEA++ + SDVW G+ L I+ G+ P+ + E ++ +
Sbjct: 218 -GFTSPEALDVKPISTASDVWGVGV-LAYILLSGQSPFQADSATESLKKTQ 72
>35671
Length = 567
Score = 46.6 bits (109), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 18/47 (38%), Positives = 31/47 (65%)
Frame = -3
Query: 471 ERGYRMVRPDNCPEELYQLMRLCWKERPEDRPTFDYLRSVLEDFFTA 517
++G R+ +P +C +E Y++M CW E E+RPTF L V+E+ + +
Sbjct: 565 QKGNRLAKPISCTDEAYKVMLQCWTESREERPTFKKLVPVMENLYRS 425
>01392
Length = 1806
Score = 45.4 bits (106), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 34/115 (29%), Positives = 54/115 (46%), Gaps = 12/115 (10%)
Frame = -1
Query: 364 QIAEGMAFIEERNYIHRDLRAANIL---VSDTLSCKIADFGLARLIE-DNEYTAREGAKF 419
IA + F+ + HRDL+ NIL + D + KI DF LA I D + T
Sbjct: 1767 HIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGISCDGDGTKTPELLT 1588
Query: 420 PI---KWTAPEAINY-----GTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEV 466
P+ ++ APE ++ ++ + D+WS GI+L I+ G P+ G +
Sbjct: 1587 PVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILY-IMLCGYPPFYGQCGEDC 1426
>19761
Length = 473
Score = 45.1 bits (105), Expect = 8e-05, Method: Compositional matrix adjust.
Identities = 32/127 (25%), Positives = 61/127 (48%), Gaps = 4/127 (3%)
Frame = -3
Query: 364 QIAEGMAFIEERN--YIHRDLRAANILVSDTLSCKIADFGLARLIED--NEYTAREGAKF 419
Q A + ++ +HRDL+ NI V++ ++ D GLAR + + T++ G
Sbjct: 399 QTASALNYMHTHTPVILHRDLKPQNIYVTEKGDVRLGDLGLARKLTGPADFATSQVGT-- 226
Query: 420 PIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRP 479
I + +PE ++ + KSD+WS G + +I G+ M ++ + G ++ P
Sbjct: 225 -IMYLSPEILSQQPYNSKSDIWSLGCVFYDIT--GKKGSDEMGVMFLLVQVMGGRKLPLP 55
Query: 480 DNCPEEL 486
D+ +E
Sbjct: 54 DHYSQEF 34
>26560
Length = 398
Score = 44.3 bits (103), Expect = 1e-04, Method: Composition-based stats.
Identities = 29/98 (29%), Positives = 51/98 (52%), Gaps = 1/98 (1%)
Frame = -1
Query: 362 AAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPI 421
AA++ G+ + R ++RDL+ ANIL+ + +I+D GLA A G
Sbjct: 338 AAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGLACDFSKKRPHASVGTH--- 168
Query: 422 KWTAPEAINYG-TFTIKSDVWSFGILLTEIVTHGRIPY 458
+ APE + G ++ +D +SFG +L +++ G P+
Sbjct: 167 GYMAPEVLMKGQSYDSSADWFSFGCMLYKLLK-GHSPF 57
>09606
Length = 1300
Score = 43.9 bits (102), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 37/149 (24%), Positives = 62/149 (41%), Gaps = 21/149 (14%)
Frame = -3
Query: 335 LLPTGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLS 394
L GSL D L + T + D + G+ +I + DLR + +L+ +
Sbjct: 890 LCTGGSLADILAQDHHLPET--SIRDFGIHLVTGLHYIHSLGILFHDLRPSKVLLDTSGV 717
Query: 395 CKIADFGLARLIEDNE-----YTAREGAKFPIK----------------WTAPEAINYGT 433
K ADFGL+++ +N A G ++ I+ + APE
Sbjct: 716 LKFADFGLSKVEGENLEELFFKFAEAGDQWNIQSAEEMMKQVPTSGSPTYMAPEVFQGAE 537
Query: 434 FTIKSDVWSFGILLTEIVTHGRIPYPGMT 462
+I SD+W+ G + E+ + G P+ G T
Sbjct: 536 PSIMSDLWALGCVFYEMFS-GHPPFLGET 453
>13066
Length = 551
Score = 42.0 bits (97), Expect = 6e-04, Method: Compositional matrix adjust.
Identities = 25/84 (29%), Positives = 39/84 (46%), Gaps = 3/84 (3%)
Frame = +3
Query: 364 QIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGL--ARLIEDNEYTAREGAKFPI 421
Q+ + ++ + HRDL+ NIL+S + K+ADFG A + E E
Sbjct: 300 QMTTALNYLHSYDVAHRDLKCENILLSSHFNVKLADFGFACACITESGEKYMSRTYCGSA 479
Query: 422 KWTAPEAINYGTFTIK-SDVWSFG 444
+ APE + + K +D WS G
Sbjct: 480 AYAAPEIVYGAPYAPKVADAWSLG 551
>11185
Length = 473
Score = 42.0 bits (97), Expect = 6e-04, Method: Compositional matrix adjust.
Identities = 31/133 (23%), Positives = 56/133 (42%), Gaps = 21/133 (15%)
Frame = +1
Query: 360 DMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNE-----YTAR 414
D + G+ +I + DLR + +L+ + K ADFGL+++ +N A
Sbjct: 13 DFGIHLVTGLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAE 192
Query: 415 EGAKFPIK----------------WTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPY 458
G ++ I+ + APE +I SD+W+ G + E+ + R+
Sbjct: 193 AGDQWNIQSAEEMMKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSGSRL-- 366
Query: 459 PGMTNPEVIQNLE 471
+PE + LE
Sbjct: 367 SAKPSPEFLNLLE 405
>21433
Length = 590
Score = 42.0 bits (97), Expect = 6e-04, Method: Compositional matrix adjust.
Identities = 25/89 (28%), Positives = 41/89 (46%)
Frame = +2
Query: 364 QIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKW 423
Q++ + + R IHRD++ N+L+ KIADFG + + T G + +
Sbjct: 191 QLSSALEYCHYRKVIHRDIKPENLLLGLKGDLKIADFGWSVHAPSSRRTTMCGT---LDY 361
Query: 424 TAPEAINYGTFTIKSDVWSFGILLTEIVT 452
PE + T D+WS G+L E +
Sbjct: 362 LPPEMVEGKTHDENVDLWSLGVLCYEFLV 448
>17975
Length = 449
Score = 42.0 bits (97), Expect = 7e-04, Method: Composition-based stats.
Identities = 38/153 (24%), Positives = 63/153 (41%), Gaps = 5/153 (3%)
Frame = +3
Query: 256 KVAVKSL---KQGSMSPDAFLAEANLMKQLQHQRLVRLYAVV-TQEPIYIITEYMENDTL 311
KVAVK + K +S E MK +QH +VRLY V+ TQ +Y+I E + +
Sbjct: 48 KVAVKVIDKTKLDEVSRSHLFQEVRCMKLVQHPNVVRLYEVIDTQTKLYLILELGDGGDM 227
Query: 312 LDSQLEEKGLGASPWGNLGQQLLLLPTGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAF 371
D + G G++ + K QI E +++
Sbjct: 228 YDYIMRHSG-----------------------------GLEEKLAK--RYFRQIVEAISY 314
Query: 372 IEERNYIHRDLRAANILVSDTLS-CKIADFGLA 403
+ + +HRDL+ N++ + K+ DFG +
Sbjct: 315 CHKLHVVHRDLKPENVVFFEKPGLVKLTDFGFS 413
>03240
Length = 1683
Score = 41.6 bits (96), Expect = 7e-04, Method: Compositional matrix adjust.
Identities = 64/314 (20%), Positives = 121/314 (38%), Gaps = 55/314 (17%)
Frame = -3
Query: 235 VERLGAGQFGEVWMGYYNGHTKV-AVKSLKQGSM----SPDAFLAEANLMKQLQHQRLVR 289
++ LG G FGEV + N + A+K+L++ + AE +++ + ++ +V+
Sbjct: 1276 IKTLGVGAFGEVSLCRKNDTGMLYAMKTLRKSDVLKRNQVAHVKAERDILAEADNEWVVK 1097
Query: 290 LY-AVVTQEPIYIITEYMENDTLLDSQLEEKGLGASPWGNLGQQLLLLPTGSLVDFLKTP 348
LY + +Y + +Y +P G L+ L
Sbjct: 1096 LYYSFQDHNYLYFVMDY------------------------------VPGGDLMGLLIRM 1007
Query: 349 SGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLA---RL 405
+ + + A++ + + + +IHRD++ NIL+ K+ DFGL R
Sbjct: 1006 EILDEPLARFY--VAELVQAIESVHRMGFIHRDIKPDNILIDRNGHIKLTDFGLCTGFRW 833
Query: 406 IEDNEYTAREGAKF---------------------PIK-------------------WTA 425
+++Y R+G P++ + A
Sbjct: 832 THNSKYYQRDGTHARQDSMEVKCQLDEQCQCEILKPLERRRKREQRCLAHSLVGTPNYIA 653
Query: 426 PEAIN-YGTFTIKSDVWSFGILLTEIVTHGRIPY----PGMTNPEVIQNLERGYRMVRPD 480
PE ++ G +T D WS G++L E++ G P+ P T +VI N + ++ R
Sbjct: 652 PEVLSRLGGYTSVCDWWSVGVILFEMLV-GHPPFYANTPAETQYKVI-NWKDMLKIPRES 479
Query: 481 NCPEELYQL-MRLC 493
N + L +RLC
Sbjct: 478 NLSQPAKDLILRLC 437
>12786
Length = 460
Score = 40.4 bits (93), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 30/108 (27%), Positives = 52/108 (48%), Gaps = 22/108 (20%)
Frame = -3
Query: 378 IHRDLRAAN-ILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPI-KWTAPEAINYGT-- 433
IH DL+ AN +LV+ L K+ DFG+A ++ ++ + + ++ + +PEAI
Sbjct: 344 IHSDLKPANFMLVAGNL--KLIDFGIANTLQQDKTSVLKDSRVGTPSYMSPEAIMAACDD 171
Query: 434 ------------------FTIKSDVWSFGILLTEIVTHGRIPYPGMTN 463
++SDVWS G +L +V +GR P+ + N
Sbjct: 170 SADDSMEEDGHRTKPKYKVGVRSDVWSLGCILYNMV-YGRTPFQHIKN 30
>18481
Length = 437
Score = 40.0 bits (92), Expect = 0.002, Method: Composition-based stats.
Identities = 20/64 (31%), Positives = 36/64 (56%), Gaps = 3/64 (4%)
Frame = -1
Query: 352 KLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCK---IADFGLARLIED 408
+ T+ +L ++ Q+ + FI ++ +IHRDL+ N L+ C I DFGL++ +D
Sbjct: 209 RFTLKTILMVSDQLLSRLEFIHQKCFIHRDLKPDNFLMGLGRHCHRLYIIDFGLSKRYKD 30
Query: 409 NEYT 412
+ T
Sbjct: 29 TQGT 18
>28638
Length = 1458
Score = 40.0 bits (92), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 31/111 (27%), Positives = 55/111 (49%), Gaps = 4/111 (3%)
Frame = -1
Query: 346 KTPSGIKLTINKLLDMAAQIAEGMAFIE--ERNYIHRDLRAANILVSD--TLSCKIADFG 401
+T G+ L + + A Q+ + F+ E N IH DL+ NIL+ + + KI DFG
Sbjct: 861 QTLEGVSLNLTR--KFAQQLCTALLFLATPEMNIIHCDLKPENILLCNPKRSAIKIVDFG 688
Query: 402 LARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVT 452
+ + Y + ++F + +PE + + + D+WS G +L E+ T
Sbjct: 687 SSCQLGQRIYQYIQ-SRF---YRSPEVLLGVPYDLAIDMWSLGCILVEMHT 547
>17286
Length = 489
Score = 39.7 bits (91), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 18/60 (30%), Positives = 35/60 (58%)
Frame = +3
Query: 44 PASPLQDNLVIALHSYEPSHDGDLGFEKGEQLRILEQSGEWWKAQSLTTGQEGFIPFNFV 103
P + ++ A++ + P DG+LGF++G+ + ++ Q E W S+ G+ G+ P N+V
Sbjct: 3 PTAGVKQPCARAIYDFLPESDGELGFQEGDMITLISQVDENWFEGSV-HGKVGYFPINYV 179
>29243
Length = 1147
Score = 39.7 bits (91), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 29/100 (29%), Positives = 47/100 (47%), Gaps = 2/100 (2%)
Frame = +2
Query: 101 NFVAKANSLEPEPWFFKNLSRKDAERQLLAPGNTHGSFLIRESES--TAGSFSLSVRDFD 158
++V + SLE W+ + R A++ L + G+FLIR + + G SLS++
Sbjct: 269 DYVNEPCSLESYNWYVGIMERPVAQKXLDTCPD--GTFLIRVTNNPLRRGELSLSIK--- 433
Query: 159 QNQGEVVKHYKIRNLDNGGFYISPRITFPGLHELVRHYTN 198
V+H K+ G FY++ F + LV HY N
Sbjct: 434 --YANAVRHIKVNRNPQGRFYLADGRYFDNIQSLVDHYEN 547
>32264
Length = 287
Score = 39.3 bits (90), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 18/45 (40%), Positives = 27/45 (60%)
Frame = +1
Query: 470 LERGYRMVRPDNCPEELYQLMRLCWKERPEDRPTFDYLRSVLEDF 514
+E GYR+ + P+ +Y+LM CW+ PE RP F L + L+D
Sbjct: 1 IEDGYRLQQNPQTPDSVYKLMLRCWEYVPEKRPHFKELYTSLKDI 135
>16708
Length = 1397
Score = 39.3 bits (90), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 16/45 (35%), Positives = 27/45 (60%)
Frame = -1
Query: 361 MAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARL 405
+A Q + I E +H D++A N+LV +CK+ D+G+A+L
Sbjct: 1079 IAGQXVCALEHIHELGVVHMDVKADNVLVDAHGNCKLTDYGIAQL 945
>27405
Length = 532
Score = 38.1 bits (87), Expect = 0.009, Method: Compositional matrix adjust.
Identities = 24/80 (30%), Positives = 38/80 (47%)
Frame = -3
Query: 362 AAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPI 421
AA++ G+ + R ++RDL+ ANIL+ + +I+D GLA + A G
Sbjct: 236 AAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGLACDFSKKKPHASVGTH--- 66
Query: 422 KWTAPEAINYGTFTIKSDVW 441
+ APE + G S W
Sbjct: 65 GYMAPEVLMKGQAYDSSADW 6
>27287
Length = 514
Score = 37.0 bits (84), Expect = 0.018, Method: Compositional matrix adjust.
Identities = 15/43 (34%), Positives = 24/43 (55%)
Frame = -2
Query: 476 MVRPDNCPEELYQLMRLCWKERPEDRPTFDYLRSVLEDFFTAT 518
M +P E++ +M CW+E P DRP+F L L+ T++
Sbjct: 513 MKKPPYASSEMFGIMHSCWQEDPNDRPSFSRLVQELDKMLTSS 385
>21210
Length = 518
Score = 36.6 bits (83), Expect = 0.023, Method: Compositional matrix adjust.
Identities = 25/85 (29%), Positives = 42/85 (49%), Gaps = 3/85 (3%)
Frame = +3
Query: 426 PEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNP-EVIQNLERGYRMVRPDN--C 482
P A ++G + ++SDVWS GI L E+ T GR PY + + +Q + RG P +
Sbjct: 42 PRASSHG-YDVRSDVWSLGITLMELAT-GRFPYRKWVSIFDQLQQVVRGVAPCLPHDGAF 215
Query: 483 PEELYQLMRLCWKERPEDRPTFDYL 507
+ + C + + RP ++ L
Sbjct: 216 SHDFVNFVNKCLTKDEKQRPKYNKL 290
>32000
Length = 644
Score = 36.2 bits (82), Expect = 0.030, Method: Compositional matrix adjust.
Identities = 30/97 (30%), Positives = 48/97 (49%), Gaps = 3/97 (3%)
Frame = -1
Query: 392 TLSCKIADFGLARL--IEDNEYTAREGAKFPIKWTAPEAINYGTF-TIKSDVWSFGILLT 448
T KIADFGLAR+ + YT + + APE + F ++ D+WS G +
Sbjct: 581 TAKMKIADFGLARVFGLPVRTYTHEV---ITLWYRAPEILLGCRFYSVPVDIWSLGCIFV 411
Query: 449 EIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDNCPEE 485
E++T R +PG + +++ YR+ R P+E
Sbjct: 410 EMMTR-RALFPGDS------EIDQLYRIFRTLGTPDE 321
>37602
Length = 804
Score = 36.2 bits (82), Expect = 0.032, Method: Compositional matrix adjust.
Identities = 15/48 (31%), Positives = 30/48 (62%)
Frame = -1
Query: 353 LTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADF 400
LT ++ + + +G+ ++ R +HRD++ ANIL+++ K+ADF
Sbjct: 228 LTEPQIAFVCRETLKGLHYLHRRGKMHRDIKGANILLTEEGDVKLADF 85
>07933
Length = 728
Score = 35.8 bits (81), Expect = 0.049, Method: Compositional matrix adjust.
Identities = 14/29 (48%), Positives = 16/29 (55%)
Frame = +3
Query: 479 PDNCPEELYQLMRLCWKERPEDRPTFDYL 507
P+ CP LY +M CW P RPTF L
Sbjct: 3 PNYCPNLLYNIMMQCWSAEPSARPTFHKL 89
>38046
Length = 446
Score = 34.7 bits (78), Expect = 0.11, Method: Composition-based stats.
Identities = 14/25 (56%), Positives = 20/25 (80%)
Frame = -1
Query: 365 IAEGMAFIEERNYIHRDLRAANILV 389
IA+ MA++E+ N+IHR+L NILV
Sbjct: 98 IADAMAYMEKENFIHRNLGDRNILV 24
>20559
Length = 430
Score = 34.3 bits (77), Expect = 0.12, Method: Composition-based stats.
Identities = 21/67 (31%), Positives = 37/67 (55%), Gaps = 4/67 (5%)
Frame = -2
Query: 235 VERLGAGQFGEVWMGY-YNGHTKVAVKSLK---QGSMSPDAFLAEANLMKQLQHQRLVRL 290
+E++G G +G V+ H VA+K ++ P + L E L+K+L+H+ +VRL
Sbjct: 360 LEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHRNIVRL 181
Query: 291 YAVVTQE 297
+ V+ E
Sbjct: 180 HDVLHSE 160
>29590
Length = 320
Score = 33.9 bits (76), Expect = 0.18, Method: Composition-based stats.
Identities = 14/41 (34%), Positives = 27/41 (65%)
Frame = +3
Query: 423 WTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTN 463
+ APE ++Y +I++D+WS G+L ++T P+ G+T+
Sbjct: 72 YVAPEVLDYEPLSIQTDMWSLGVLSYVMLTACS-PFVGITS 191
>11228
Length = 2155
Score = 33.1 bits (74), Expect = 0.29, Method: Compositional matrix adjust.
Identities = 20/40 (50%), Positives = 25/40 (62%)
Frame = -1
Query: 114 WFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLS 153
W+ L R AE +LL + GS+L+RESES GSF LS
Sbjct: 1972 WYHGRLGRAGAE-ELLRDQDA-GSYLVRESESKLGSFVLS 1859
>37260
Length = 401
Score = 32.7 bits (73), Expect = 0.33, Method: Composition-based stats.
Identities = 19/69 (27%), Positives = 35/69 (50%)
Frame = -1
Query: 101 NFVAKANSLEPEPWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLSVRDFDQN 160
+F+ L+ W++ LS ++AE +L+ GSFL+R+S + SLS +
Sbjct: 221 DFLESMKQLKDCGWYWGPLSYEEAESKLM--DKRDGSFLVRDSSNENYILSLSFKSMGHV 48
Query: 161 QGEVVKHYK 169
++H+K
Sbjct: 47 HHTRIEHHK 21
>15741
Length = 402
Score = 32.3 bits (72), Expect = 0.55, Method: Composition-based stats.
Identities = 14/42 (33%), Positives = 20/42 (47%)
Frame = -3
Query: 347 TPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANIL 388
T + LT A +A GMA + +HRD+ A N+L
Sbjct: 127 TSTANDLTARDFFSFALHVARGMAHVANNKIVHRDVAARNVL 2
>13664
Length = 507
Score = 32.0 bits (71), Expect = 0.69, Method: Composition-based stats.
Identities = 16/56 (28%), Positives = 27/56 (48%)
Frame = +2
Query: 42 NPPASPLQDNLVIALHSYEPSHDGDLGFEKGEQLRILEQSGEWWKAQSLTTGQEGF 97
+P S + V+AL+ Y+ +L G+ + +L + E W L GQ+GF
Sbjct: 338 SPLGSTRKPKKVVALYDYKAQRSDELTILSGDVIMLLHKDSESWWMGELLDGQQGF 505
>36481
Length = 806
Score = 31.6 bits (70), Expect = 0.87, Method: Compositional matrix adjust.
Identities = 17/53 (32%), Positives = 27/53 (50%)
Frame = +2
Query: 340 SLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDT 392
S+ DFLK S I ++ ++ Q+ + F+ E H DL+ NIL D+
Sbjct: 623 SVFDFLKDNSYGAYPIEQVRHISYQLCYAVNFLHENQLTHTDLKPENILFVDS 781
>06462
Length = 1511
Score = 30.8 bits (68), Expect = 1.2, Method: Compositional matrix adjust.
Identities = 30/116 (25%), Positives = 48/116 (41%), Gaps = 6/116 (5%)
Frame = +1
Query: 112 EPWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLSVRDFDQNQGEVVKHYKIR 171
E W+ +SR++AE+ L G FL+RES F LS ++ G+ + +
Sbjct: 1090 ELWYHGKMSRREAEKLL----GKDGDFLVRESGHNXSQFVLS----GKHHGQFI---HLL 1236
Query: 172 NLDNGGFYISPRITFPGLHELVRHYTN-----ASDGLCTRLSRPCQTQKPQ-KPWW 221
+D G + F + LV ++ + S G L RP P +P W
Sbjct: 1237 LVDPDGIVRTKDYIFDNISHLVSYHCHHGMPIVSHGSQLTLLRPINVSVPAYRP*W 1404
>20131
Length = 574
Score = 30.8 bits (68), Expect = 1.4, Method: Compositional matrix adjust.
Identities = 15/53 (28%), Positives = 28/53 (52%), Gaps = 1/53 (1%)
Frame = -2
Query: 54 IALHSYEPSHDGDLGFEKGEQLRILEQSGEWWKAQSLTTGQE-GFIPFNFVAK 105
+A++SY DL F +G+ + + ++ +WW T G++ G P +V K
Sbjct: 471 VAMYSYVSGETADLTFNEGDMILVTKKDEDWWTG---TLGEKTGMFPSTYVKK 322
>32357
Length = 625
Score = 30.8 bits (68), Expect = 1.5, Method: Compositional matrix adjust.
Identities = 17/52 (32%), Positives = 33/52 (63%), Gaps = 1/52 (1%)
Frame = -2
Query: 233 KLVERLGAGQFGEVWMGYYN-GHTKVAVKSLKQGSMSPDAFLAEANLMKQLQ 283
+L++++G+G FGE+++G +N +VAVK + + P + E+ L + LQ
Sbjct: 429 RLMKKIGSGSFGEIYLGVHNTSGEEVAVKLELKNAKHPQLYY-ESKLYRVLQ 277
>17516
Length = 453
Score = 29.3 bits (64), Expect = 4.1, Method: Compositional matrix adjust.
Identities = 27/104 (25%), Positives = 50/104 (48%), Gaps = 7/104 (6%)
Frame = -3
Query: 423 WTAPEAI-NYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRM-VRPD 480
+ APE + G + +K+DV+S I+L E+ +G+ +++ + LE + +RP
Sbjct: 421 YMAPEVLLQKGQYDMKADVYSLAIILWEL-WYGQDAADHISS-HLFGRLEDAVQAGLRPS 248
Query: 481 ---NC--PEELYQLMRLCWKERPEDRPTFDYLRSVLEDFFTATE 519
C P++ +L++ W+ RPT EDF T+
Sbjct: 247 VTMTCKPPDDWLKLLQSGWEFHASKRPTSRDAAEFFEDFLERTK 116
>25100
Length = 699
Score = 28.9 bits (63), Expect = 5.8, Method: Compositional matrix adjust.
Identities = 11/38 (28%), Positives = 19/38 (50%)
Frame = +3
Query: 184 ITFPGLHELVRHYTNASDGLCTRLSRPCQTQKPQKPWW 221
+T+ + L+ +T+ L + SR C+ K K WW
Sbjct: 150 LTYCSSYILIHMHTDTHKDLFLKFSRKCRENKADKIWW 263
>18050
Length = 448
Score = 28.5 bits (62), Expect = 6.6, Method: Compositional matrix adjust.
Identities = 16/57 (28%), Positives = 29/57 (50%), Gaps = 1/57 (1%)
Frame = +3
Query: 53 VIALHSYEPSHDGDLGFEKGEQLRILEQSGE-WWKAQSLTTGQEGFIPFNFVAKANS 108
VIA HSYE L E G+ + + + + W++ + + G G+ P ++ + NS
Sbjct: 24 VIAKHSYESDEPDVLQLELGDVVNVSRKLPDGWYQGERIRDGAVGWFPGSYTEELNS 194
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000362663 | hsapiens_gene_ensembl | Proto-oncogene
tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK) (Lymphocyte
cell-specific protein-tyrosine kinase) (LSK) (T cell- specific
protein-tyrosine kinase). [Source:Uniprot/SWISSPROT;Acc:P06239]
(539 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
06405 285 4e-77
21808 268 3e-72
11780 190 3e-68
04852 155 4e-38
09007 147 8e-36
07291 138 5e-33
17300 122 5e-31
07940 127 8e-30
20640 124 8e-29
14116 108 5e-24
18996 107 9e-24
17637 105 5e-23
22005 81 3e-22
08294 98 9e-21
13305 84 1e-16
01718 83 2e-16
14477 80 2e-15
19301 74 2e-13
07833 68 8e-12
29581 67 2e-11
00715 67 2e-11
01060 66 4e-11
13592 64 2e-10
12672 63 3e-10
18484 63 3e-10
14126 63 3e-10
18921 63 3e-10
12721 62 4e-10
25550 60 2e-09
01707 60 2e-09
01756 59 4e-09
17253 59 6e-09
00300 58 1e-08
14420 55 6e-08
01966 55 6e-08
19094 55 7e-08
04591 53 3e-07
30755 51 1e-06
21079 50 2e-06
15910 49 4e-06
04138 49 4e-06
13212 49 4e-06
31885 49 5e-06
27546 48 8e-06
26711 47 2e-05
07836 47 2e-05
35671 47 3e-05
01392 45 6e-05
19761 45 8e-05
26560 44 1e-04
09606 44 2e-04
17975 42 7e-04
11185 42 7e-04
21433 42 7e-04
13066 42 7e-04
03240 42 0.001
12786 40 0.002
18481 40 0.002
28638 40 0.002
17286 40 0.003
29243 40 0.003
32264 39 0.004
16708 39 0.005
27405 38 0.011
27287 37 0.019
21210 37 0.025
37602 36 0.033
32000 36 0.033
07933 35 0.051
38046 35 0.11
20559 34 0.12
29590 33 0.20
11228 33 0.31
37260 33 0.41
15741 32 0.56
13664 32 0.72
36481 32 0.91
20131 31 1.4
06462 31 1.4
32357 31 1.4
17516 29 4.5
25100 29 5.6
18050 28 6.3
>06405
Length = 1965
Score = 285 bits (729), Expect = 4e-77, Method: Compositional matrix adjust.
Identities = 162/382 (42%), Positives = 229/382 (59%), Gaps = 8/382 (2%)
Frame = +1
Query: 155 ESESTAGSFSLSVRDFDQNQGEVVKHYKIRNLDNGGFYISPRITFPGLHELVRHYTNASD 214
ESES+ G S+SVR F+ V HY+I D+G +++ F L ELV H++ +D
Sbjct: 1 ESESSPGQRSISVR-FEGR----VYHYRITE-DDGKVFVTQEHRFNTLAELVHHHSIHAD 162
Query: 215 GLCTRLSRPCQTQKPQKPWW------EDEWEVPRETLKLVERLGAGQFGEVWMGYYNGHT 268
GL T L P K QKP D WE+ R + + RLG GQ+G+V+ + +
Sbjct: 163 GLVTTLLYPAP--KRQKPTVFGVSPEPDRWEIERTEIAMKHRLGGGQYGDVYEAMWKRYN 336
Query: 269 K-VAVKSLKQGSMSPDAFLAEANLMKQLQHQRLVRLYAVVTQE-PIYIITEYMENDTLLD 326
K VAVK+LK+ +M+ + FL EA +MK+++H LV+L V T+E P YI+TE+M
Sbjct: 337 KIVAVKTLKEDTMALNDFLEEAAIMKEMKHPNLVQLLGVCTREPPFYIVTEFM------- 495
Query: 327 SQLEEKGLGASPWGNLGQQLLLLPTGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIE 386
P G+L+D+L++ + + L+ MA QIA GMA++E
Sbjct: 496 -----------------------PHGNLLDYLRSSTREENGPTALMYMATQIASGMAYLE 606
Query: 387 ERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGT 446
+N+IHRDL A N LV+D+ K+ADFGLARL++D+ YTA GAKFPIKWTAPE + +
Sbjct: 607 TKNFIHRDLAARNCLVADSNMVKVADFGLARLMKDDTYTAHIGAKFPIKWTAPEGLAFNR 786
Query: 447 FTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDNCPEELYQLMRLC 506
F+ +SD+W+FG+LL E+ T+G PYPG+ EV LERGYRM RP P ++Y LM C
Sbjct: 787 FSTRSDIWAFGVLLWELATYGMSPYPGVELTEVYHLLERGYRMERPPGTPADVYILMLKC 966
Query: 507 WKERPEDRPTFDYLRSVLEDFF 528
W+ P+DRPTF + +LE+ F
Sbjct: 967 WQWDPKDRPTFKEIHFLLENMF 1032
>21808
Length = 1011
Score = 268 bits (684), Expect(2) = 3e-72, Method: Compositional matrix adjust.
Identities = 138/255 (54%), Positives = 175/255 (68%), Gaps = 1/255 (0%)
Frame = +1
Query: 262 GYYNGHTKVAVKSLKQGSMSPDAFLAEANLMKQLQHQRLVRLYAVVTQ-EPIYIITEYME 320
G +N T VA+K+LK G+M P FLAEA +MK+L+H +L++LYAV TQ +PI+IITE M+
Sbjct: 4 GLWNNTTPVAIKTLKSGTMDPKDFLAEAQIMKKLRHPKLIQLYAVCTQDDPIFIITELMK 183
Query: 321 NDTLLDSQLEEKGLGASPWGNLGQQLLLLPTGSLVDFLKTPSGIKLTINKLLDMAAQIAE 380
N GSL++FL+ G L + L+D+ AQIA
Sbjct: 184 N------------------------------GSLLEFLQG-KGRVLKLPALIDIGAQIAC 270
Query: 381 GMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPE 440
GMA++E +NYIHRDL A NILVSD + KIADFGLAR+I+++EY AR GA+FPIKWTAPE
Sbjct: 271 GMAYLESQNYIHRDLAARNILVSDNNTVKIADFGLARVIKEDEYEARVGARFPIKWTAPE 450
Query: 441 AINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDNCPEELY 500
A NY FTIKSDVWSFGILLTE VT+GR+PYPGMTN EV+ +E GYRM P CP+ LY
Sbjct: 451 AANYNRFTIKSDVWSFGILLTETVTYGRVPYPGMTNAEVLHQVEHGYRMPCPPGCPKPLY 630
Query: 501 QLMRLCWKERPEDRP 515
+M CW++ +RP
Sbjct: 631 DIMLECWRKEEMERP 675
Score = 23.1 bits (48), Expect(2) = 3e-72, Method: Compositional matrix adjust.
Identities = 13/29 (44%), Positives = 17/29 (58%)
Frame = +2
Query: 508 KERPEDRPTFDYLRSVLEDFFTATEGQYQ 536
K R D PTF+ L+ LE+FFT Y+
Sbjct: 656 KRRWRD-PTFETLQWKLEEFFTMDSKDYR 739
>11780
Length = 1713
Score = 190 bits (482), Expect(2) = 3e-68, Method: Compositional matrix adjust.
Identities = 126/371 (33%), Positives = 189/371 (50%), Gaps = 10/371 (2%)
Frame = +3
Query: 82 FEKGEQLRILEQSGE--WWKAQSLTTGQEGFIPFNFVA--KANSLEPEPWFFKNLSRKDA 137
F+KG+ L I + + W+KA + G+EG IP N+V K +L PWF ++R+ A
Sbjct: 111 FQKGDLLVIRRATSDRMWYKACD-SNGREGMIPANYVQPRKVVTLHAMPWFHGKITRQQA 287
Query: 138 ERQLLAPGNTHGSFLIRESESTAGSFSLSVRDFDQNQGEVVKHYKIRNLDNGGFYISPRI 197
E +LL P G FLIRES + G ++L V + V+HY+I +N I
Sbjct: 288 E-ELLKP-REDGLFLIRESSNYPGDYTLCVCHLGK-----VEHYRILYRENQ-LTIDEEG 443
Query: 198 TFPGLHELVRHYTNASDGLCTRLSRPCQTQKPQ------KPWWEDEWEVPRETLKLVERL 251
F L ELV+HY +DGLCT+L+RP Q + + W + + L++ E +
Sbjct: 444 FFRNLDELVKHYLADADGLCTQLTRPVTKQGGNFGTVSLQEFKSGGWVIAXQDLEIGEAI 623
Query: 252 GAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPDAFLAEANLMKQLQHQRLVRLYAVVTQEP 311
G G FG+V+ G Y G VA+K LK +FL EA++M L+H LVRL VV E
Sbjct: 624 GKGDFGDVYKGMYRGQP-VAIKQLKDKDRGEQSFLQEASVMTSLRHDNLVRLIGVVLGET 800
Query: 312 IYIITEYMENDTLLDSQLEEKGLGASPWGNLGQQLLLLPTGSLVDFLKTPSGIKLTINKL 371
I+++TE+M G+LV++L++ +T
Sbjct: 801 IFLVTEFM------------------------------GKGNLVEYLRSRGRSVITKKDQ 890
Query: 372 LDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAK 431
++ A M ++E + +HRDL A N+LV D K++DFGLA+ + ++ + K
Sbjct: 891 INFATDTCAAMEYLESKRLVHRDLAARNVLVHDDGKAKVSDFGLAKFGDFSQTS----VK 1058
Query: 432 FPIKWTAPEAI 442
FPIKWTAPEA+
Sbjct: 1059FPIKWTAPEAL 1091
Score = 87.4 bits (215), Expect(2) = 3e-68, Method: Compositional matrix adjust.
Identities = 39/80 (48%), Positives = 56/80 (70%)
Frame = +1
Query: 447 FTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDNCPEELYQLMRLC 506
FT KSD+WSFGILL EI + GR+PYP + +V+ ++ERGYRM P+ CP E+Y +M+
Sbjct: 1105 FTSKSDMWSFGILLWEIYSFGRVPYPRIPLTDVVMHVERGYRMEAPEGCPPEIYSIMKQA 1284
Query: 507 WKERPEDRPTFDYLRSVLED 526
W+ P +RPTF + + L +
Sbjct: 1285 WELDPNERPTFKSVLARLNN 1344
>04852
Length = 1462
Score = 155 bits (392), Expect = 4e-38, Method: Compositional matrix adjust.
Identities = 99/261 (37%), Positives = 137/261 (52%), Gaps = 8/261 (3%)
Frame = +1
Query: 268 TKVAVKSLKQ--GSMSPDAFLAEANLMKQLQ----HQRLVRLYAVVTQE-PIYIITEYME 320
+ VAVK L+ ++ F+ E +MK ++ H +V TQ P+++I E+ +
Sbjct: 22 STVAVKMLRDIVTAVEEQDFVQELQVMKAVKKMGSHINIVNFLGCCTQGGPLWVIVEFAK 201
Query: 321 NDTLLDSQLEEKGLGASPWGNLGQQLLLLPTGSLVDFLKTPSGIKLTINKLLDMAAQIAE 380
N L D LE G + +G + + KTP G + LL A QIA
Sbjct: 202 NGNLRDF-LESCRDGINGYGKF------VSPQDPGWYTKTPGGHVIRRKNLLSYAFQIAR 360
Query: 381 GMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPE 440
GM F+ R IHRDL A N+LV++ KIADFGL+R + Y R G + P+KW APE
Sbjct: 361 GMEFLASRKCIHRDLAARNVLVTEEHVLKIADFGLSR--TGDYYKKRSGGRLPVKWMAPE 534
Query: 441 AINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQN-LERGYRMVRPDNCPEEL 499
A+ +T KSDVWSFG++L EI + G +PY + N E+ L+ YRM RP+ L
Sbjct: 535 ALFDMRYTTKSDVWSFGVVLWEIFSLGGMPYASIPNEELYSKLLDDAYRMPRPELASGNL 714
Query: 500 YQLMRLCWKERPEDRPTFDYL 520
Y +M CW RP DRP F L
Sbjct: 715 YAIMERCWLNRPSDRPEFSQL 777
>09007
Length = 1440
Score = 147 bits (372), Expect = 8e-36, Method: Compositional matrix adjust.
Identities = 90/296 (30%), Positives = 147/296 (49%), Gaps = 15/296 (5%)
Frame = -1
Query: 240 VPRETLKLVERLGAGQFGEV----WMGYYNGHTKVAVKSLKQGSMSPDA--FLAEANLMK 293
+ ++ + L + LG G FG V W +VAVK L + + D FL E +M+
Sbjct: 888 ISKDCVALSKSLGQGHFGTVRQAIWTAESGEKVQVAVKCLSKDKIHKDGQEFLKETAIMQ 709
Query: 294 QLQHQRLVRLYAVVTQE--PIYIITEYMENDTLLDSQLEEKGLGASPWGNLGQQLLLLPT 351
L H+ +VR+Y VV I ++TE L P
Sbjct: 708 MLDHENIVRVYGVVMDNGADIMLVTE------------------------------LAPM 619
Query: 352 GSLVDFLKTPSG-IKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKI 410
SL++ +K S + ++ +L D + Q+ +GM+++E + +HRDL A NIL+ KI
Sbjct: 618 RSLLECVKEVSARVDFSVPRLCDFSQQVCDGMSYLESKRLVHRDLAARNILLFSKSKVKI 439
Query: 411 ADFGLA-RLIEDNEYTAREGA---KFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTH 466
+D G++ L EY + + + W APE+ F+ SDVW+FG+LL E TH
Sbjct: 438 SDVGVSGALGAGKEYYQSQQTIHLQNAVAWCAPESFRNLCFSSASDVWAFGVLLWEFFTH 259
Query: 467 GRIPYPGMTNPEVIQNLE--RGYRMVRPDNCPEELYQLMRLCWKERPEDRPTFDYL 520
G P+ G+ ++++ ++ + R+ +PD CP+E Y +M CW++ P+ RPTF L
Sbjct: 258 GFQPWAGLNGQQIMEAVDAPQSQRLEQPDLCPKEYYAVMLKCWEQEPQRRPTFSQL 91
>07291
Length = 833
Score = 138 bits (348), Expect = 5e-33, Method: Compositional matrix adjust.
Identities = 67/164 (40%), Positives = 104/164 (63%), Gaps = 2/164 (1%)
Frame = +1
Query: 366 LTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLA-RLIEDNEY 424
LT+ +LLD QIA+GMA+++E +HR+L A N +V++ +++D+G+ L + Y
Sbjct: 40 LTVVQLLDFGRQIADGMAYLQEVKVVHRNLAARNCIVTEDGRLQLSDYGVTGSLFPQSYY 219
Query: 425 TAREG-AKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNL 483
TA + A+ +KW APE I+ F+ KSDVW+FG++L E++T G PYP + N ++ L
Sbjct: 220 TADDSPARDLVKWMAPETIDNFHFSSKSDVWAFGVVLWELLTRGITPYPDVENSSLLPYL 399
Query: 484 ERGYRMVRPDNCPEELYQLMRLCWKERPEDRPTFDYLRSVLEDF 527
+ G+RM +P PE +Y++M CW E PE RP F L L+ F
Sbjct: 400 KEGHRMKKPKQSPEPVYEMMTACWNESPEQRPDFAELNDQLKTF 531
>17300
Length = 480
Score = 122 bits (306), Expect(2) = 5e-31, Method: Composition-based stats.
Identities = 57/116 (49%), Positives = 82/116 (70%), Gaps = 4/116 (3%)
Frame = +1
Query: 378 IAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIE----DNEYTAREGAKFP 433
I+ GM + + Y+HRDL A NILV++ L CK+ADFGL+R IE + YT + G K P
Sbjct: 1 ISSGMGXLADMGYVHRDLAARNILVNEILVCKVADFGLSREIESDTTEGAYTTK-GGKIP 177
Query: 434 IKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRM 489
++WTAPEAI Y FT SDVWSFG+++ E++++G PY +N +VI+ +E+GYR+
Sbjct: 178 VRWTAPEAIAYRKFTSASDVWSFGVVMWEVMSYGERPYWNWSNQDVIKAVEKGYRL 345
Score = 30.4 bits (67), Expect(2) = 5e-31, Method: Composition-based stats.
Identities = 13/39 (33%), Positives = 19/39 (48%)
Frame = +2
Query: 494 NCPEELYQLMRLCWKERPEDRPTFDYLRSVLEDFFTATE 532
+CPE L+QLM W++ RP + L+ A E
Sbjct: 356 DCPEALHQLMLDAWQKERSHRPKMSMVVKTLDKLIRAPE 472
>07940
Length = 1336
Score = 127 bits (320), Expect = 8e-30, Method: Compositional matrix adjust.
Identities = 95/279 (34%), Positives = 134/279 (48%), Gaps = 41/279 (14%)
Frame = -3
Query: 237 EWEVPRETLKLVERLGAGQFGEVW----MGYY--NGHTKVAVKSLKQGSMSPDA--FLAE 288
+WE PRE L L +RLG G FG V MG + N VAVK LK+ + + + E
Sbjct: 860 KWEFPRERLVLGDRLGEGAFGLVMKGEAMGIFKDNNSVTVAVKMLKEDATDREMMDLIRE 681
Query: 289 ANLMKQL-QHQRLVRLYAVVTQE-PIYIITEYMENDTLLDSQLEEKGLGAS--------- 337
+MK + +H+ ++ L TQ +Y+I E+ + L D + G S
Sbjct: 680 MEMMKVIGKHKNIINLLGCCTQRGALYVIVEFAPHGNLRDFLKSHRPHGTSYSCIADYEQ 501
Query: 338 ----------------PWGNLGQQLLLLPTGSLVDFLKTPSGIK-----LTINKLLDMAA 376
G L +P S V F T S + LT L+ A
Sbjct: 500 PVITSSSSSFSHPNSASSSAQGTSLGFIPGTSTVSF-STGSHRQDMLKMLTPKDLISYAY 324
Query: 377 QIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTARE-GAKFPIK 435
Q+A GM ++ + IHRDL A N+LV++ KIADFGL R ++ +Y + + P+K
Sbjct: 323 QVARGMEYLASKQCIHRDLAARNVLVAEEYVLKIADFGLTRNLQQFDYYRKTTDGRLPVK 144
Query: 436 WTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGM 474
W APEA+ +T KSDVWS+G+LL EI T G PYP +
Sbjct: 143 WMAPEALFDRKYTSKSDVWSYGVLLWEIFTLGGNPYPSV 27
>20640
Length = 1492
Score = 124 bits (312), Expect = 8e-29, Method: Compositional matrix adjust.
Identities = 61/146 (41%), Positives = 84/146 (57%), Gaps = 1/146 (0%)
Frame = +1
Query: 388 RNYIHRDLRAANILVSDTLSCKIADFGLARLIED-NEYTAREGAKFPIKWTAPEAINYGT 446
R Y+HRDL N LV L KI+DFGLAR + + Y E PI+W EAI Y
Sbjct: 1 RGYVHRDLATRNCLVGHDLVVKISDFGLARSVHSVDYYRGSEHDAIPIRWMPLEAILYNK 180
Query: 447 FTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDNCPEELYQLMRLC 506
F+ +SDVWSFG++L EI PY G+T+ EV++ ++ G + P+ P +Y+LM+ C
Sbjct: 181 FSTQSDVWSFGVVLWEIFAFALQPYYGLTHEEVVRFVKEGKVLACPERTPPPMYELMKQC 360
Query: 507 WKERPEDRPTFDYLRSVLEDFFTATE 532
W RP RP+F L LE+ + E
Sbjct: 361 WHRRPATRPSFHTLHKTLENMHSKYE 438
>14116
Length = 1017
Score = 108 bits (271), Expect = 5e-24, Method: Compositional matrix adjust.
Identities = 73/243 (30%), Positives = 115/243 (47%), Gaps = 10/243 (4%)
Frame = -1
Query: 240 VPRETLKLVERLGAGQFGEVWMGYYN-----GHTKVAVKSLKQGS---MSPDAFLAEANL 291
+ RE L + E +G G FG V G+ G VAVK+L + + +FL EA +
Sbjct: 645 IDREFLTMGEEIGKGNFGCVKRGFLTLPEQKGDILVAVKTLHNNNPREIELQSFLQEALI 466
Query: 292 MKQLQHQRLVRLYAVVTQEPIYIITEYMENDTLLDSQLEEKGLGASPWGNLGQQLLLLPT 351
MK H ++ L + L++ L P+ +
Sbjct: 465 MKDFHHSNVLTLIGICLN-------------------LDDMPLVVLPF---------MKH 370
Query: 352 GSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIA 411
G L+ +++ + TI L+ IA GM ++ ++HRDL A N ++ + K+A
Sbjct: 369 GDLLTYIRDDQH-QPTIKDLIMYGVDIARGMDYLAGLKFVHRDLAARNCMLDEDFHVKVA 193
Query: 412 DFGLARLIEDNEYTAREG--AKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRI 469
DFGLAR I + EY + E AK P+KW A E++ G + K+DVWS+G++L E++T G
Sbjct: 192 DFGLARDIYEKEYYSSENKKAKLPVKWMALESLEKGNYDSKTDVWSYGVVLWELLTRGSD 13
Query: 470 PYP 472
P
Sbjct: 12 ALP 4
>18996
Length = 491
Score = 107 bits (268), Expect = 9e-24, Method: Compositional matrix adjust.
Identities = 61/140 (43%), Positives = 82/140 (58%), Gaps = 6/140 (4%)
Frame = +2
Query: 391 IHRDLRAANILVSDTLSCKIADFGLARLIE-DNEYTAREGAKFPIKWTAPEAINYGTFTI 449
IHRDL A NILV D KI+DFGLA+ D Y PIKW +PEAI F+
Sbjct: 2 IHRDLAARNILV-DRSCVKISDFGLAQFANADGYYYGISQRDIPIKWYSPEAIETCKFSS 178
Query: 450 KSDVWSFGILLTEIVTHGRIP--YPG--MTNPEVIQNLERGYRMVRPDNCPEELY-QLMR 504
SDVWS+G+ L E+ + G IP PG +T E + L +G R+ +P+ C + +Y +LMR
Sbjct: 179 YSDVWSYGVTLFEMFSRGEIPNLLPGHDLTQEEFLNRLRKGERLPKPELCSDFVYSELMR 358
Query: 505 LCWKERPEDRPTFDYLRSVL 524
CW E P+ RPTF + ++
Sbjct: 359 PCWHEMPKSRPTFHQIIQII 418
>17637
Length = 447
Score = 105 bits (261), Expect = 5e-23, Method: Compositional matrix adjust.
Identities = 50/132 (37%), Positives = 77/132 (58%), Gaps = 1/132 (0%)
Frame = +1
Query: 399 NILVSDTLSCKIADFGLARLIEDNEYTAR-EGAKFPIKWTAPEAINYGTFTIKSDVWSFG 457
N ++ D L K+ D L+R + +Y +G PIKW + EA+ + SDVWSFG
Sbjct: 1 NCVIDDQLRVKLTDSALSRDLFSGDYNCLGDGEYRPIKWLSLEALQKSHYNEGSDVWSFG 180
Query: 458 ILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDNCPEELYQLMRLCWKERPEDRPTF 517
+L+ E+ T G++PY + E+ L+ GYR+ +P NCP+EL+ +M CW P +RP+F
Sbjct: 181 VLMWEMCTLGKLPYAEIDPYEMEHYLKDGYRLAQPFNCPDELFTIMAYCWASMPAERPSF 360
Query: 518 DYLRSVLEDFFT 529
L+ L +F T
Sbjct: 361 SQLQICLSEFHT 396
>22005
Length = 873
Score = 81.3 bits (199), Expect(2) = 3e-22, Method: Compositional matrix adjust.
Identities = 67/198 (33%), Positives = 101/198 (51%), Gaps = 18/198 (9%)
Frame = +1
Query: 285 FLAEANLMKQLQHQRLVRLYAVVT-QEPIYIITEYME----NDTLLDSQLEEKGLGASPW 339
F EA+LM H +V+L V +P+ ++ E+M ND L E L S
Sbjct: 151 FEREASLMADFDHPNIVKLLGVCAIGKPMCLLFEFMSKGDLNDFLRLCSPENYNLPVSRS 330
Query: 340 GNLGQQLLLLPTGSLVDFL------------KTPSGIKLTINKLLDMAAQIAEGMAFIEE 387
NL ++ L G V+ + SG+ T ++L ++ QI+ GMA++ +
Sbjct: 331 QNL---VVDLEDGLRVEVEAEECEKDTQSEDRDCSGMLXTKDQLY-ISQQISAGMAYLAQ 498
Query: 388 RNYIHRDLRAANILVSDTLSCKIADFGLARLIED-NEYTAREGAKFPIKWTAPEAINYGT 446
++Y+HRDL A + S T I+DFGLAR + + Y E PI+W EAI Y
Sbjct: 499 KDYVHRDL-ATRTVXSRTT*S*ISDFGLARSVHSVDYYRGSEQDAIPIRWMPLEAILYSK 675
Query: 447 FTIKSDVWSFGILLTEIV 464
F+ +SDVWSFG++L EI+
Sbjct: 676 FSTQSDVWSFGVVLWEIL 729
Score = 42.0 bits (97), Expect(2) = 3e-22, Method: Compositional matrix adjust.
Identities = 16/42 (38%), Positives = 28/42 (66%)
Frame = +3
Query: 470 PYPGMTNPEVIQNLERGYRMVRPDNCPEELYQLMRLCWKERP 511
PY G+T+ EV+ ++ G + +P P ++Y+LM+ CW+ RP
Sbjct: 744 PYYGLTHEEVVNYVKAGKILEQPTKTPHQVYELMKQCWQRRP 869
>08294
Length = 1849
Score = 97.8 bits (242), Expect = 9e-21, Method: Compositional matrix adjust.
Identities = 60/215 (27%), Positives = 103/215 (47%)
Frame = +2
Query: 310 EPIYIITEYMENDTLLDSQLEEKGLGASPWGNLGQQLLLLPTGSLVDFLKTPSGIKLTIN 369
EP ++ITEY + WG+L Q LL T + + L ++
Sbjct: 926 EPHFLITEYCD------------------WGDLKQ--FLLATRNDNGRGRGTRVPALALS 1045
Query: 370 KLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREG 429
+ L M Q+A GM + + +H DL A N+L++ + K+A L+ + +EY
Sbjct: 1046 QKLGMGQQVAAGMEALSNQGLVHGDLAARNVLLTSRMQLKVARPALSGDVYASEYYPLHQ 1225
Query: 430 AKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRM 489
P++W PE + + T DVW+FG+ L E++ +PY M++ EV+++L+
Sbjct: 1226 RLVPLRWLPPEGVLEDSATTCGDVWAFGVFLWEVLQLADLPYRLMSDEEVLRSLQHSQAA 1405
Query: 490 VRPDNCPEELYQLMRLCWKERPEDRPTFDYLRSVL 524
+ + P L L++ C ++P RP F + SVL
Sbjct: 1406 LDSPDAPPALLSLLQRCTAQQPSQRPPFSEICSVL 1510
>13305
Length = 549
Score = 84.3 bits (207), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 37/89 (41%), Positives = 52/89 (58%)
Frame = +2
Query: 429 GAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYR 488
+ PI+W A E++ T+T +SDVWSFG++L EI T G PY ++ L+ GYR
Sbjct: 2 STRVPIRWMAVESLFNNTYTTQSDVWSFGVVLWEIFTLGGTPYSSTDTQQLFAFLKDGYR 181
Query: 489 MVRPDNCPEELYQLMRLCWKERPEDRPTF 517
+ RP C + Y +M CW E + RPTF
Sbjct: 182 LKRPKLCDQNTYAMMLQCWNENAQRRPTF 268
>01718
Length = 959
Score = 83.2 bits (204), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 76/282 (26%), Positives = 122/282 (43%), Gaps = 13/282 (4%)
Frame = +3
Query: 247 LVERLGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPDAFLAEANLMKQLQHQRLVRLYAV 306
+ E++GAG F EV+ + +V + + + L E L+ +LQH ++R V
Sbjct: 159 ICEKIGAGFFSEVFKVTHRITGQVMALKMNTMTSNRHNMLREVQLLNRLQHANILRFMGV 338
Query: 307 VTQE-PIYIITEYMENDTLLDSQLEEKGLGASPWGNLGQQLLLLPTGSLVDFLKTPSGIK 365
E ++ +TEY+ + L QL EK PW I+
Sbjct: 339 CVHEGQLHALTEYIPSGNL--EQLLEKKDEELPW---------------------TQRIQ 449
Query: 366 LTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILV----SDTLSCKIADFGLARLIE- 420
LT+ +A G+ ++ +IHRDL + NIL+ + IADFGLA I
Sbjct: 450 LTLG--------LARGLDYLHSTRFIHRDLTSKNILIRREDNHGYHAVIADFGLATKIPD 605
Query: 421 --DNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPE 478
D E G+ + W APE +N + ++D++S GI++ EI RIP +P+
Sbjct: 606 PLDKEKLPTVGSPY---WMAPEVLNGHFYNERADLFSVGIIMCEIT--ARIP----ADPD 758
Query: 479 V---IQNLERGYRMVRP--DNCPEELYQLMRLCWKERPEDRP 515
+ + N Y + CP + QL C + P+ RP
Sbjct: 759 IMPRMNNFGVDYVALSEMISYCPLDYLQLAFKCCQVDPQKRP 884
>14477
Length = 493
Score = 79.7 bits (195), Expect = 2e-15, Method: Composition-based stats.
Identities = 55/188 (29%), Positives = 87/188 (46%), Gaps = 8/188 (4%)
Frame = -1
Query: 250 RLGAGQFGEVWMGYY---NGHTKVAVKSLKQGSMSPDA---FLAEANLMKQLQHQRLVRL 303
+LGAG FG V G + VA+K LK + P + EA +MK++ H +VRL
Sbjct: 469 KLGAGNFGSVMKGVCRLDDREIPVAIKVLKNADLDPSVQSELIKEAEVMKKMDHMHIVRL 290
Query: 304 YAVVTQEPIYIITEYMENDTLLDSQLEEKGLGASPWGNLGQQLLLLPTGSLVDFLKTPSG 363
+ E + ++ E L G L FL P
Sbjct: 289 IGLCEGETMMLVLE------------------------------LAKLGPLNKFL--PKN 206
Query: 364 IKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLI--ED 421
L + +L++ Q+++GM ++E ++HRDL A NIL+ D KI+DFG+++ + E+
Sbjct: 205 KHLPLWNILELMWQVSQGMEYLEANKFVHRDLAARNILLCDEHFAKISDFGMSKTLSREN 26
Query: 422 NEYTAREG 429
N Y A+E
Sbjct: 25 NYYMAQEA 2
>19301
Length = 712
Score = 73.6 bits (179), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 53/183 (28%), Positives = 85/183 (46%), Gaps = 1/183 (0%)
Frame = +2
Query: 235 EDEWEVPRETLKLVERLGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPDAFLAEANLMKQ 294
+D+WE+P E++ +E LG+G G V++G +VAVK ++ D + +++
Sbjct: 281 QDDWEIPFESITDLEWLGSGAQGAVFLGKLCAE-EVAVKKVR------DIKETDIRNLRK 439
Query: 295 LQHQRLVRLYAVVTQEPIY-IITEYMENDTLLDSQLEEKGLGASPWGNLGQQLLLLPTGS 353
L H ++ V TQ P Y II EY P G
Sbjct: 440 LNHPNIISFKGVCTQAPCYCIIMEY------------------------------CPYGQ 529
Query: 354 LVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADF 413
L + L+ G ++ +LD + QIA GM ++ IHRDL++ N+LV+ KI+DF
Sbjct: 530 LYEVLR--DGKEIPPALVLDWSKQIASGMNYLHSHKIIHRDLKSPNVLVAKNDVVKISDF 703
Query: 414 GLA 416
G +
Sbjct: 704 GTS 712
>07833
Length = 1504
Score = 68.2 bits (165), Expect = 8e-12, Method: Compositional matrix adjust.
Identities = 53/186 (28%), Positives = 91/186 (48%), Gaps = 8/186 (4%)
Frame = -3
Query: 348 LLPTGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIE--ERNYIHRDLRAANILVSDT 405
+P GSL + L SGI + N+ L A IA GM F+ E + L + ++++ +
Sbjct: 1376 FMPFGSLYNTLHGESGIVVDQNQSLRFAMDIARGMEFLHSMEPTIPNFLLTSKHVMIDED 1197
Query: 406 LSCKI--ADFGLARLIEDNEYTAREGAKFPIKWTAPEAINY---GTFTIKSDVWSFGILL 460
L+ +I AD+ + +G + W APEA+ T +D+WSF IL+
Sbjct: 1196 LTARINMADYCFS--------FHEKGKVYSPAWMAPEALQRRPDDINTRAADMWSFAILM 1041
Query: 461 TEIVTHGRIPYPGMTNPEV-IQNLERGYRMVRPDNCPEELYQLMRLCWKERPEDRPTFDY 519
E+ T +P+ +++ EV ++ G R+ P + +L+++C E P RP FD
Sbjct: 1040 WELETR-EVPFAELSSMEVGMKVALEGLRISIPPGISLHMSRLIKICMNEEPGKRPRFDM 864
Query: 520 LRSVLE 525
+ +LE
Sbjct: 863 IIPILE 846
>29581
Length = 1278
Score = 67.0 bits (162), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 54/215 (25%), Positives = 99/215 (46%), Gaps = 8/215 (3%)
Frame = -2
Query: 275 LKQGSMSPDAFLAEANLMKQLQHQRLVRLYAVV---TQEPIYIITEYMENDTLLDSQLEE 331
L++ +SP + + L+HQ +V+L VV + + ++++ EY E D
Sbjct: 1244 LERDMVSPSVVCVRSTFLLNLRHQNIVQLQEVVVGKSLDSLFLVMEYCEQDL-------- 1089
Query: 332 KGLGASPWGNLGQQLLLLPTGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYI 391
SL+D + P + +++ + Q+ +G+ ++ E I
Sbjct: 1088 --------------------ASLLDNMPAP----FSESQVKCIVLQLLKGLRYLHEAFII 981
Query: 392 HRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFP----IKWTAPEAI-NYGT 446
HRDL+ +N+L++D KIADFGLAR Y + P + + APE + T
Sbjct: 980 HRDLKVSNLLMTDKGCVKIADFGLAR-----NYGKPQKPMTPKVVTLWYRAPELLFGSKT 816
Query: 447 FTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQ 481
+ D+WS G +L E++ H + PG ++ + I+
Sbjct: 815 HSTAIDMWSAGCILGELLGHKPL-MPGRSDLQQIE 714
>00715
Length = 1788
Score = 66.6 bits (161), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 49/172 (28%), Positives = 82/172 (47%), Gaps = 27/172 (15%)
Frame = +1
Query: 372 LDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLI------------ 419
L +A Q+A G+ ++ N +H DL+ AN L++ L +IADFG +
Sbjct: 247 LSLALQMARGLHYLHSINIVHLDLKPANCLLTRDLKLRIADFGCCHQLTPTGLDMGEREG 426
Query: 420 ----EDNEYTAREGA-----KFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIP 470
+ E T +GA + + APE + +++SDV+S GI L ++ T + P
Sbjct: 427 GMAGNELELTPVQGAWKNELAGTLAYRAPELLKGLQPSVRSDVYSLGITLWQMCTR-QGP 603
Query: 471 YPGMTNPEVI-QNLERGYRMVRPDNCPEELYQLM-----RLCWKERPEDRPT 516
Y G+ V+ Q + + R P + ++ +++M CW R EDRPT
Sbjct: 604 YEGVPAHAVVYQVVSKDLRPCPPPSTEDDPFEVMFRDLYTQCWARRVEDRPT 759
>01060
Length = 1800
Score = 65.9 bits (159), Expect = 4e-11, Method: Compositional matrix adjust.
Identities = 60/260 (23%), Positives = 115/260 (44%), Gaps = 6/260 (2%)
Frame = +1
Query: 237 EWEVPRETLKLVERLGAGQFGEVWMGYYNGH-TKVAVKSLK-QGSMS--PDAFLAEANLM 292
++E L +++G G +G V+ + K+A+K ++ +GS P + + E ++
Sbjct: 55 DFETALSDLTDFQKIGEGTYGVVYKCRHRATGRKLAMKKIRLRGSEDGVPSSAIREIAML 234
Query: 293 KQLQHQRLVRLYAVVTQ-EPIYIITEYMENDTLLDSQLEEKGLGASPWGNLGQQLLLLPT 351
++L+H +V L V+ + E ++++ E++ D +
Sbjct: 235 RELRHTNIVCLEDVIMEDERLFLVFEFLSMDLKM-------------------------- 336
Query: 352 GSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIA 411
+D K P G+ L + QI G+ F +R +HRDL+ N+L++ T + KIA
Sbjct: 337 --YID--KFPEGVVLDRRLVKSYVFQIVTGIXFCHQRRIVHRDLKPQNLLINHTGAIKIA 504
Query: 412 DFGLARLIEDNEYTAREGAKFPIKWTAPEAI-NYGTFTIKSDVWSFGILLTEIVTHGRIP 470
DFG+AR A + + APE + ++ DVWS G + +++ I
Sbjct: 505 DFGMARTFA-LPVRAYTHEVVTLWYRAPEILMGASKYSTPVDVWSIGTIFADML----IR 669
Query: 471 YPGMTNPEVIQNLERGYRMV 490
P I L + +R++
Sbjct: 670 TPIFKGDSEIDQLFKIFRII 729
>13592
Length = 980
Score = 63.9 bits (154), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 61/282 (21%), Positives = 124/282 (43%), Gaps = 17/282 (6%)
Frame = +2
Query: 250 RLGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPDAFLAEANLMKQLQ------HQRLVRL 303
++G G+FG+V+ N ++ ++K+ ++ P A N+ ++L+ H+ LVR
Sbjct: 5 KIGQGRFGKVYTAVNNNTGELM--AMKEIAIQPGETRALKNVAEELKILEGIKHKNLVRY 178
Query: 304 YAV-VTQEPIYIITEYMENDTLLDSQLEEKGLGASPWGNLGQQLLLLPTGSLVDFLKTPS 362
Y + V +E + I E L G+L ++
Sbjct: 179 YGIEVHREELLIFME------------------------------LCSEGTLESLVELTG 268
Query: 363 GIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANI-LVSDTLSCKIADFGLARLIED 421
G+ +++ AQ+ G+A + + +HRD++ ANI LV + S K+ DFG A I+
Sbjct: 269 GLPEALSR--RFTAQLLSGVAELHKHGIVHRDIKTANIFLVDGSNSLKLGDFGSAVKIQA 442
Query: 422 NE--------YTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPG 473
+ Y + P +T + +G +D+WS G ++ E+ + G+ P+
Sbjct: 443 HTTVPGELQGYVGTQAYMAPEVFTKTNSDGHGRL---ADIWSVGCVVVEMAS-GKRPWAQ 610
Query: 474 M-TNPEVIQNLERGYRMVRPDNCPEELYQLMRLCWKERPEDR 514
+N +++ + G + P++ +E + + C + P+ R
Sbjct: 611 FDSNFQIMFKVGMGEKPQAPESLSQEGHDFIDHCLQHDPKQR 736
>12672
Length = 773
Score = 63.2 bits (152), Expect = 3e-10, Method: Compositional matrix adjust.
Identities = 43/166 (25%), Positives = 72/166 (43%), Gaps = 17/166 (10%)
Frame = +3
Query: 379 AEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPI---K 435
A G+ ++ + ++HRD++ ANIL+ + K+ DF E + A I
Sbjct: 21 ASGIQYLNDNGHVHRDIKTANILLDSEYTAKVGDFATVVSAPSGEGKTVQNASVVIGTAA 200
Query: 436 WTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIP--------------YPGMTNPEVIQ 481
+ APEAI++ T K D +SFG++L E++T G + + PE I
Sbjct: 201 YLAPEAIHFDVST-KLDSYSFGVVLLEVIT-GLVAQDYSREERTLSSHIMENVEEPEEIH 374
Query: 482 NLERGYRMVRPDNCPEELYQLMRLCWKERPEDRPTFDYLRSVLEDF 527
+ PD ++LY + C + RP +R LE+
Sbjct: 375 DFVDQSAGTWPDGAVDKLYDISMRCLNLSKKQRPNVKDIRPELEEL 512
>18484
Length = 635
Score = 63.2 bits (152), Expect = 3e-10, Method: Compositional matrix adjust.
Identities = 39/140 (27%), Positives = 70/140 (50%)
Frame = +1
Query: 375 AAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPI 434
AA+IA G+ F+ ++ I+RDL+ N+++ KIADFG+ + + T R P
Sbjct: 61 AAEIAVGLFFLHDQGIIYRDLKLDNVMLDSEGHIKIADFGMCKEGMTGDATTRTFCGTP- 237
Query: 435 KWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDN 494
+ APE + Y ++ D W++G+LL E++ G+ P+ G E+ ++ + + P
Sbjct: 238 DYIAPEIVLYQPYSKSVDWWAYGVLLFEMLA-GQPPFDGEDEDELFSSI-TDHNVSYPKA 411
Query: 495 CPEELYQLMRLCWKERPEDR 514
E L + + P R
Sbjct: 412 MSREAVSLCKGLLMKNPTKR 471
>14126
Length = 1265
Score = 62.8 bits (151), Expect = 3e-10, Method: Compositional matrix adjust.
Identities = 60/232 (25%), Positives = 98/232 (42%), Gaps = 14/232 (6%)
Frame = +3
Query: 248 VERLGAGQFGEVWMG--YYNGHTKVAVKSLKQGSMS---PDAFLAEANLMKQLQ---HQR 299
V +G G +G V+ N VA+K ++ + P + E +++KQL+ H
Sbjct: 204 VAVIGNGAYGTVYKARDLRNQGEFVAMKRIRLNNTEEGMPMMAIREISMLKQLEQYEHPN 383
Query: 300 LVRLYAV----VTQEPIYI--ITEYMENDTLLDSQLEEKGLGASPWGNLGQQLLLLPTGS 353
+VRL V +T I + + EY+E+D L P LG
Sbjct: 384 VVRLLDVSHNTITDREIRLNLVFEYIEHDL-------ATYLAKCPSPGLG---------- 512
Query: 354 LVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADF 413
P IK D+ Q+ G+ F+ +HRDL+ N+L+S K+ADF
Sbjct: 513 -------PDRIK-------DLMLQLLNGVDFLHSNRIVHRDLKPQNLLISKDGRLKLADF 650
Query: 414 GLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVT 465
GLAR+ + + A + + +PE + + D+WS G + E+ T
Sbjct: 651 GLARIY--SFHMALTTVVVTLWYRSPEVLMQAEYGTSVDIWSCGCIFAELFT 800
>18921
Length = 697
Score = 62.8 bits (151), Expect = 3e-10, Method: Compositional matrix adjust.
Identities = 53/226 (23%), Positives = 98/226 (43%), Gaps = 3/226 (1%)
Frame = +2
Query: 241 PRETLKLVERLGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPDA--FLAEANLMKQLQHQ 298
P + ++ +LG G +G V+ + +V ++KQ + D + E ++M+Q +
Sbjct: 23 PEDVFDILGKLGEGSYGSVFKSLHKETGQVL--AIKQVPVDTDLQEIIKEISIMQQCDSK 196
Query: 299 RLVRLY-AVVTQEPIYIITEYMENDTLLDSQLEEKGLGASPWGNLGQQLLLLPTGSLVDF 357
+V+ Y + ++I+ EY GA GS+ D
Sbjct: 197 YIVKYYGSYFKNTDLWIVMEY---------------CGA---------------GSVSDI 286
Query: 358 LKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLAR 417
++ + L ++ + +G+ ++ R IHRD++A NIL+++ K+ADFG+A
Sbjct: 287 MRLRNK-TLVEREIATILYYTLKGLXYLHSRRKIHRDIKAGNILLNNEGHAKLADFGVAG 463
Query: 418 LIEDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEI 463
+ D P W APE I + +D+WS GI E+
Sbjct: 464 QLTDTMAKRNTVIGTPY-WMAPEVIQEIGYDCVADIWSLGITALEM 598
>12721
Length = 821
Score = 62.4 bits (150), Expect = 4e-10, Method: Compositional matrix adjust.
Identities = 48/226 (21%), Positives = 94/226 (41%), Gaps = 2/226 (0%)
Frame = +1
Query: 241 PRETLKLVERLGAGQFGEVWMGYYNGHTKVAVKSLK-QGSMSPDAFLAEANLMKQLQHQR 299
PR L ++G G G V + ++AVK + + + E +M+ H
Sbjct: 82 PRTFLDDFMKIGEGSTGIVCIATSRDGRQMAVKKMDLRKQQRRELLFNEVVVMRDYHHPN 261
Query: 300 LVRLY-AVVTQEPIYIITEYMENDTLLDSQLEEKGLGASPWGNLGQQLLLLPTGSLVDFL 358
+V +Y + + + ++++ E+ME L D + T + +D +
Sbjct: 262 IVEMYNSYLVNDELWVVMEFMEGGALTD----------------------IVTNNRMDEV 375
Query: 359 KTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARL 418
+ + + + L AF+ IHRD+++ +IL+S K+ DFG
Sbjct: 376 QIATVCRACLKAL-----------AFLHANGVIHRDIKSDSILLSHDGKVKLXDFGFCAQ 522
Query: 419 IEDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIV 464
+ + + P W APE I+ + + D+WS GI++ E++
Sbjct: 523 VTQDLQKRKSLVGTPY-WMAPEVISRLPYGPEVDIWSLGIMVMEMI 657
>25550
Length = 941
Score = 60.5 bits (145), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 28/63 (44%), Positives = 39/63 (61%)
Frame = +3
Query: 469 IPYPGMTNPEVIQNLERGYRMVRPDNCPEELYQLMRLCWKERPEDRPTFDYLRSVLEDFF 528
+ YPG+ EV LERGYRM RP P ++Y LM CW+ P++RPTF + +LE+ F
Sbjct: 36 VXYPGVDLTEVYHLLERGYRMERPQGTPADVYILMLKCWQWDPKERPTFKEIHYLLENMF 215
Query: 529 TAT 531
+
Sbjct: 216 EKS 224
>01707
Length = 757
Score = 60.1 bits (144), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 61/242 (25%), Positives = 111/242 (45%), Gaps = 8/242 (3%)
Frame = +1
Query: 243 ETLKLVERLGAGQFGEVWMGYYNGHTK-VAVKSLKQGSMSP---DAFLAEANLMKQLQHQ 298
E + + ++G G +G V+ ++ VA+K + P + E ++KQL+H
Sbjct: 64 EKYEKIGKIGEGSYGVVFKCRNKETSQLVAIKKFVESEDDPLIKKIAMREIRMLKQLKHP 243
Query: 299 RLVRLYAVVTQEP-IYIITEYMENDTLLDSQLEEKGLGASPWGNLGQQLLLLPTGSLVDF 357
LVRL V ++ ++++ +Y+++ TLL+ L P G
Sbjct: 244 NLVRLIEVFRRKKRLHLVFDYVDH-TLLNE------LDRYPRG----------------- 351
Query: 358 LKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLAR 417
L P ++ LL + F + N IHRD++ NIL++ K+ DFG AR
Sbjct: 352 LPEPMVKRIIYQTLL--------AVNFCHQYNTIHRDVKPENILITRQGQVKLCDFGFAR 507
Query: 418 LIE--DNEYTAREGAKFPIKWTAPEAINYGT-FTIKSDVWSFGILLTEIVTHGRIPYPGM 474
++ +EYT ++ + APE + T + DVW+ G + E++T G+ +PG
Sbjct: 508 ILTGPGDEYTDYVATRW---YRAPELLVGDTQYGPPVDVWAIGCVFAELLT-GQALWPGR 675
Query: 475 TN 476
++
Sbjct: 676 SD 681
>01756
Length = 1858
Score = 59.3 bits (142), Expect = 4e-09, Method: Compositional matrix adjust.
Identities = 60/253 (23%), Positives = 101/253 (39%), Gaps = 24/253 (9%)
Frame = -3
Query: 241 PRETLKL-----------VERLGAGQFGEVWMGYYN------GHTKVAVKSLKQGSMSPD 283
P ETLK + ++G G FGEV+ KV + + K+G P
Sbjct: 1781 PYETLKFPFCDEDAKYEKLAKIGQGTFGEVFKARCKKTKQVVAMKKVLMDNEKEGF--PI 1608
Query: 284 AFLAEANLMKQLQHQRLVRLYAVVTQEPIYIITEYMENDTLLDSQLEEKGLGASPWGNLG 343
L E +++ L H+ +V L + + K A+ + ++
Sbjct: 1607 TALREIKILQLLNHENVVDLIEICST----------------------KATSANRYKSMF 1494
Query: 344 QQLLLLPTGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVS 403
+ L L S + + ++ ++ Q+ G+ +I +HRD++AANIL++
Sbjct: 1493 YLVFEFCEHDLAGLLSNMSVV-FNLPEIKEVMKQLMNGLYYIHRNKILHRDMKAANILIT 1317
Query: 404 DTLSCKIADFGLAR-----LIEDNEYTAREGAKFPIKWTAPEAINYG--TFTIKSDVWSF 456
K+ADFGLAR L + N YT R W P + G ++ D W
Sbjct: 1316 KQGVLKLADFGLARAFSVNLRQPNRYTNR----VVTLWYRPPELLLGDRNYSTAIDQWGA 1149
Query: 457 GILLTEIVTHGRI 469
G ++ E+ T I
Sbjct: 1148 GCIMAEMWTRNPI 1110
>17253
Length = 483
Score = 58.5 bits (140), Expect = 6e-09, Method: Composition-based stats.
Identities = 46/173 (26%), Positives = 78/173 (45%), Gaps = 6/173 (3%)
Frame = -1
Query: 270 VAVKSLKQGSMSPDA--FLAEANLMKQL-QHQRLVRLYAVVT-QEPIYIITEYMENDTLL 325
VAVK+ + + + FL E ++M++L +H +V T +P I+ E+ + LL
Sbjct: 459 VAVKTHNEAATDAEKSEFLRELSIMRKLPRHPNVVSFMGCCTMSDPALILMEFCCHGDLL 280
Query: 326 DSQLEEKGLGASPWGNLGQQLLLLPTGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFI 385
+ + P ++ FL T + LT A +A GMA +
Sbjct: 279 SFLRKRR-----------------PDRTV--FL-TSTANDLTARDFFSFALHVARGMAHV 160
Query: 386 EERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNE--YTAREGAKFPIKW 436
+HRD+ A N+L+S+ CK++DFGL+R + D Y P++W
Sbjct: 159 ANNKIVHRDVAARNVLISERNVCKVSDFGLSRRVGDQNDVYEIVSRRPLPLRW 1
>00300
Length = 2318
Score = 57.8 bits (138), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 61/278 (21%), Positives = 117/278 (42%), Gaps = 13/278 (4%)
Frame = -1
Query: 250 RLGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPD------AFLAEANLMKQLQHQRLVRL 303
++G GQFG+V+ + + +LK+ P+ E + + +QH+ LV+
Sbjct: 1637 KIGEGQFGKVYTAV--NMSTGELMALKEMKFQPNDLQQLREMCDEIKIFEGIQHENLVKY 1464
Query: 304 YAV-VTQEPIYIITEYMENDTLLDSQLEEKGLGASPWGNLGQQLLLLPTGSLVDFLKTPS 362
Y V V ++ + + EY + T+ + A+ G L + L+ T +V
Sbjct: 1463 YGVEVHKDEMLMFMEYCDTGTIEE---------AAKMG-LPEYLIRRYTREIV------- 1335
Query: 363 GIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDN 422
L +N L E + +HRD++ ANI ++ K+ DFG + ++ +
Sbjct: 1334 ---LAVNHL--------------HENSIVHRDIKGANIFLTSNGHVKLGDFGCSVKLKSH 1206
Query: 423 EYTAREGAKF--PIKWTAPEAI---NYGTFTIKSDVWSFGILLTEIVTHGRIPYPGM-TN 476
E + APE + G + +D+WS G ++ E+ T G+ P+ + N
Sbjct: 1205 TTMPGEFHNLVGTTAYMAPEVFTQNDQGGYGRAADIWSLGCVVIEMAT-GKRPWHDLDNN 1029
Query: 477 PEVIQNLERGYRMVRPDNCPEELYQLMRLCWKERPEDR 514
+++ + G++ PD+ E + L P R
Sbjct: 1028 YQIMYKVGIGHKPAVPDSLSVEGKHFLDLIMCHDPAQR 915
>14420
Length = 528
Score = 55.5 bits (132), Expect = 6e-08, Method: Compositional matrix adjust.
Identities = 33/126 (26%), Positives = 59/126 (46%), Gaps = 2/126 (1%)
Frame = +2
Query: 348 LLPTGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLS 407
L GSL D + + ++ + + + + F+ E IHRD+++ NIL+ S
Sbjct: 143 FLAGGSLTDVVTETC---MDEGQIAAVCRECLQALEFLHENQVIHRDIKSDNILLGMDGS 313
Query: 408 CKIADFGLARLI--EDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVT 465
K+ DFG + E ++ + G + W APE + + D+WS G++ E++
Sbjct: 314 VKLTDFGFCAQLSPEQSKRSTMVGTPY---WMAPEVVTRKQYGPTVDIWSLGVMCIEMI- 481
Query: 466 HGRIPY 471
G PY
Sbjct: 482 EGEPPY 499
>01966
Length = 1735
Score = 55.1 bits (131), Expect = 6e-08, Method: Compositional matrix adjust.
Identities = 40/153 (26%), Positives = 74/153 (48%), Gaps = 4/153 (2%)
Frame = -1
Query: 269 KVAVKSLK-QGSMS--PDAFLAEANLMKQLQHQRLVRLYAVVTQ-EPIYIITEYMENDTL 324
K+A+K ++ +GS P + + E ++++L+H +V L V+ + E ++++ E++ D
Sbjct: 1630 KLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTNIVCLEDVIMEDERLFLVFEFLSMDLK 1451
Query: 325 LDSQLEEKGLGASPWGNLGQQLLLLPTGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAF 384
+ +D K P G+ L + QI G+ F
Sbjct: 1450 M----------------------------YID--KFPEGVVLDRRLVKSYVFQIVTGINF 1361
Query: 385 IEERNYIHRDLRAANILVSDTLSCKIADFGLAR 417
+R +HRDL+ N+L++ T + KIADFG+AR
Sbjct: 1360 CHQRRIVHRDLKPQNLLINHTGAIKIADFGMAR 1262
>19094
Length = 898
Score = 55.1 bits (131), Expect = 7e-08, Method: Compositional matrix adjust.
Identities = 29/84 (34%), Positives = 45/84 (53%)
Frame = +1
Query: 380 EGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAP 439
+G+ ++ R IHRD++A NIL+++ K+ADFG+A + D P W AP
Sbjct: 91 KGL*YLHSRRKIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTP-YWMAP 267
Query: 440 EAINYGTFTIKSDVWSFGILLTEI 463
E I + +D+WS GI E+
Sbjct: 268 EVIQEIGYDCVADIWSLGITALEM 339
>04591
Length = 1117
Score = 52.8 bits (125), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 43/194 (22%), Positives = 83/194 (42%), Gaps = 12/194 (6%)
Frame = -2
Query: 282 PDAFLAEANLMKQLQHQRLVRLYAVVTQEP---------IYIITEYMENDTLLDSQLEEK 332
P L E +++QL+H+ +V+L + + Y+I EY + D
Sbjct: 1089 PITALREIKILQQLEHENVVQLQEICHTQAGPYNRYKSTFYLIFEYCDYDL--------- 937
Query: 333 GLGASPWGNLGQQLLLLPTGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIH 392
L++ L+ +K ++ ++ +Q+ G+ +I + +H
Sbjct: 936 -------------------AGLLNNLR----VKFSLADKKNLMSQLLNGLFYIHTKQILH 826
Query: 393 RDLRAANILVSDTLSCKIADFGLAR-LIEDNEYTAREGAKFPIKWTAPEAINYG--TFTI 449
RD++AANIL++ K+ADFGL+R ++ T R W P + G +
Sbjct: 825 RDIKAANILLTRDGVLKLADFGLSRPWVKSKRLTNR----VVTLWYRPPELLLGEREYGP 658
Query: 450 KSDVWSFGILLTEI 463
+ D+W G ++ E+
Sbjct: 657 EIDMWGVGCIMAEM 616
>30755
Length = 1137
Score = 50.8 bits (120), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 37/142 (26%), Positives = 69/142 (48%), Gaps = 2/142 (1%)
Frame = +2
Query: 375 AAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEY--TAREGAKF 432
A+I + ++ + I+RDL+ N+L+ K+ADFGL + ED Y T +
Sbjct: 50 GAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCK--EDITYGRTTKTFCGT 223
Query: 433 PIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRP 492
P ++ APE ++ + D W G+++ E++ GR+P+ + +V+ L + P
Sbjct: 224 P-EYLAPEVLDDNDYGRAVDWWGTGVVMYEMIC-GRLPFYNRDH-DVLFTLILVEDVKFP 394
Query: 493 DNCPEELYQLMRLCWKERPEDR 514
N +E L+ + P +R
Sbjct: 395 RNITDEAKSLLSGLLAKDPRNR 460
>21079
Length = 878
Score = 50.1 bits (118), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 31/97 (31%), Positives = 50/97 (51%), Gaps = 3/97 (3%)
Frame = +1
Query: 366 LTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANIL-VSDTLS-CKIADFGLARLIE-DN 422
LT + QI G+ ++ ++ +H DL+ N+L VSD + KI DFGLAR + +
Sbjct: 118 LTERDCVHFVRQICSGVGYMHTQSILHLDLKPENVLCVSDNSNQIKIIDFGLARFYKPGD 297
Query: 423 EYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGIL 459
G ++ APE +NY +D+WS G++
Sbjct: 298 SLQVLFGTP---EFIAPEVVNYDEINFTTDMWSIGVI 399
>15910
Length = 1361
Score = 49.3 bits (116), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 34/114 (29%), Positives = 57/114 (50%), Gaps = 3/114 (2%)
Frame = +2
Query: 376 AQIAEGMAFIEERNYIHRDLRAANIL---VSDTLSCKIADFGLARLIEDNEYTAREGAKF 432
+ I G+ +I +HRDL+ N+L ++D K+ADFGL+R+IE E
Sbjct: 485 SDILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLADFGLSRIIEP-EVQMSTVCGT 661
Query: 433 PIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERG 486
P + APE + +T D+WS G+ + I+ G P+ E+ + + +G
Sbjct: 662 P-GYCAPEVLKGDKYTPSVDMWSVGV-IAYILLCGYEPFFAENEFEMYRKIIKG 817
>04138
Length = 800
Score = 49.3 bits (116), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 32/97 (32%), Positives = 47/97 (48%), Gaps = 7/97 (7%)
Frame = +1
Query: 380 EGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLAR-----LIEDNEYTAREGAKFPI 434
E + +I +HRD++AANIL++ K+ADFGLAR L + N YT R
Sbjct: 46 ERLYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNR----VVT 213
Query: 435 KWTAPEAINYG--TFTIKSDVWSFGILLTEIVTHGRI 469
W P + G ++ D W G ++ E+ T I
Sbjct: 214 LWYRPPELLLGDRNYSTAIDQWGAGCIMAEMWTRNPI 324
>13212
Length = 1067
Score = 49.3 bits (116), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 28/93 (30%), Positives = 48/93 (51%), Gaps = 7/93 (7%)
Frame = -1
Query: 377 QIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKF--PI 434
++ + F+ + IHRD++A N+L++ K+ADFG++ N T ++ F
Sbjct: 956 EMCMALDFLHRHHVIHRDIKAGNVLLTIDGEVKLADFGVSA---KNTQTQQKRDTFIGTP 786
Query: 435 KWTAPEAINYGT-----FTIKSDVWSFGILLTE 462
W APE + T + K+D+WS G+ L E
Sbjct: 785 YWMAPEVVLCETLKDTPYDFKADIWSLGVTLIE 687
>31885
Length = 529
Score = 48.9 bits (115), Expect = 5e-06, Method: Compositional matrix adjust.
Identities = 30/111 (27%), Positives = 52/111 (46%), Gaps = 7/111 (6%)
Frame = -2
Query: 376 AQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIK 435
Q+A + ++ + +HRD++ NIL+ + C + DF +A +ED+E P
Sbjct: 351 CQLALVLDYLRSQKIVHRDIKPDNILLDEQGHCHVTDFNIATQLEDDELATSTSGTRP-- 178
Query: 436 WTAPEAINYGT-------FTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEV 479
+ APE YG + D WS G+ L E++ R P+ +N +
Sbjct: 177 YMAPEV--YGVAINERRGYGFPVDWWSLGVSLFELLKKRR-PFSVHSNTSL 34
>27546
Length = 426
Score = 48.1 bits (113), Expect = 8e-06, Method: Composition-based stats.
Identities = 33/138 (23%), Positives = 61/138 (44%), Gaps = 1/138 (0%)
Frame = -1
Query: 285 FLAEANLMKQLQHQRLVRLYAVVTQEP-IYIITEYMENDTLLDSQLEEKGLGASPWGNLG 343
F E ++ +L H ++++++++ + P I+I Y E +L S +++ G P
Sbjct: 339 FPRELEILTRLDHPNIIQIHSILQRGPKIFIFMRYAEKGDML-SHIKKTG----PIDEAQ 175
Query: 344 QQLLLLPTGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVS 403
++ Q+A+ + ++ + HRDL+ NIL+S
Sbjct: 174 TKVWFF---------------------------QMAKALQYLHSHDIAHRDLKCENILLS 76
Query: 404 DTLSCKIADFGLARLIED 421
L+ KIADFG AR D
Sbjct: 75 KRLNVKIADFGFARYCRD 22
>26711
Length = 405
Score = 47.0 bits (110), Expect = 2e-05, Method: Composition-based stats.
Identities = 33/111 (29%), Positives = 58/111 (52%), Gaps = 3/111 (2%)
Frame = -2
Query: 377 QIAEGMAFIEERNYIHRDLRAANILVS-DTL-SCKIADFGLAR-LIEDNEYTAREGAKFP 433
Q+ + + + + +H DL+ +N+L+S D L S ++ DFGLAR L E G
Sbjct: 392 QVLDILQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARKLYPPQETFLNHGTP-- 219
Query: 434 IKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLE 484
+T+PEA++ + SDVW G+ L I+ G+ P+ + E ++ +
Sbjct: 218 -GFTSPEALDVKPISTASDVWGVGV-LAYILLSGQSPFQADSATESLKKTQ 72
>07836
Length = 1478
Score = 47.0 bits (110), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 59/227 (25%), Positives = 99/227 (43%), Gaps = 45/227 (19%)
Frame = -1
Query: 335 GASPWGNLGQQLLLLPTGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNY---- 390
G W L GSL D+L + L +++L +A G+A + +
Sbjct: 1349 GTGSWTQLFLITDYHENGSLHDYLLSRV---LDSSEMLALAHSAICGLAHLHIEIFGTRG 1179
Query: 391 ----IHRDLRAANILVSDTLSCKIADFGLA-RLI-EDNEYTA----REGAKFPIKWTAPE 440
HRD+++ NILV +C IAD GLA R I E NE R+G K ++ APE
Sbjct: 1178 KPAIAHRDIKSKNILVKKNGTCCIADLGLAVRYISESNEVDVAPNPRQGTK---RYMAPE 1008
Query: 441 AI-------NYGTFTIKSDVWSFGILLTEI----VTHG-----RIPY-------PGMTNP 477
+ N+ F ++D+++FG+++ EI V G ++P+ P +
Sbjct: 1007 VLEMLLNVKNFDAFK-QADMYAFGLVMWEIARCCVIGGVAEEYQVPFYNCLPHDPSFEDV 831
Query: 478 EVIQNLERGYRMVRPDN--------CPEELYQLMRLCWKERPEDRPT 516
++ ++++ VRPD + + ++M CW P R T
Sbjct: 830 RLVVSVDK----VRPDIPLRWQEDPIMKVMVKVMCECWSGNPAARLT 702
>35671
Length = 567
Score = 46.6 bits (109), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 18/47 (38%), Positives = 31/47 (65%)
Frame = -3
Query: 484 ERGYRMVRPDNCPEELYQLMRLCWKERPEDRPTFDYLRSVLEDFFTA 530
++G R+ +P +C +E Y++M CW E E+RPTF L V+E+ + +
Sbjct: 565 QKGNRLAKPISCTDEAYKVMLQCWTESREERPTFKKLVPVMENLYRS 425
>01392
Length = 1806
Score = 45.4 bits (106), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 34/109 (31%), Positives = 53/109 (48%), Gaps = 12/109 (11%)
Frame = -1
Query: 377 QIAEGMAFIEERNYIHRDLRAANIL---VSDTLSCKIADFGLARLIE-DNEYTAREGAKF 432
IA + F+ + HRDL+ NIL + D + KI DF LA I D + T
Sbjct: 1767 HIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGISCDGDGTKTPELLT 1588
Query: 433 PI---KWTAPEAINY-----GTFTIKSDVWSFGILLTEIVTHGRIPYPG 473
P+ ++ APE ++ ++ + D+WS GI+L I+ G P+ G
Sbjct: 1587 PVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILY-IMLCGYPPFYG 1444
>19761
Length = 473
Score = 45.1 bits (105), Expect = 8e-05, Method: Compositional matrix adjust.
Identities = 32/127 (25%), Positives = 61/127 (48%), Gaps = 4/127 (3%)
Frame = -3
Query: 377 QIAEGMAFIEERN--YIHRDLRAANILVSDTLSCKIADFGLARLIED--NEYTAREGAKF 432
Q A + ++ +HRDL+ NI V++ ++ D GLAR + + T++ G
Sbjct: 399 QTASALNYMHTHTPVILHRDLKPQNIYVTEKGDVRLGDLGLARKLTGPADFATSQVGT-- 226
Query: 433 PIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRP 492
I + +PE ++ + KSD+WS G + +I G+ M ++ + G ++ P
Sbjct: 225 -IMYLSPEILSQQPYNSKSDIWSLGCVFYDIT--GKKGSDEMGVMFLLVQVMGGRKLPLP 55
Query: 493 DNCPEEL 499
D+ +E
Sbjct: 54 DHYSQEF 34
>26560
Length = 398
Score = 44.3 bits (103), Expect = 1e-04, Method: Composition-based stats.
Identities = 29/98 (29%), Positives = 51/98 (52%), Gaps = 1/98 (1%)
Frame = -1
Query: 375 AAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPI 434
AA++ G+ + R ++RDL+ ANIL+ + +I+D GLA A G
Sbjct: 338 AAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGLACDFSKKRPHASVGTH--- 168
Query: 435 KWTAPEAINYG-TFTIKSDVWSFGILLTEIVTHGRIPY 471
+ APE + G ++ +D +SFG +L +++ G P+
Sbjct: 167 GYMAPEVLMKGQSYDSSADWFSFGCMLYKLLK-GHSPF 57
>09606
Length = 1300
Score = 43.9 bits (102), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 37/149 (24%), Positives = 62/149 (41%), Gaps = 21/149 (14%)
Frame = -3
Query: 348 LLPTGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLS 407
L GSL D L + T + D + G+ +I + DLR + +L+ +
Sbjct: 890 LCTGGSLADILAQDHHLPET--SIRDFGIHLVTGLHYIHSLGILFHDLRPSKVLLDTSGV 717
Query: 408 CKIADFGLARLIEDNE-----YTAREGAKFPIK----------------WTAPEAINYGT 446
K ADFGL+++ +N A G ++ I+ + APE
Sbjct: 716 LKFADFGLSKVEGENLEELFFKFAEAGDQWNIQSAEEMMKQVPTSGSPTYMAPEVFQGAE 537
Query: 447 FTIKSDVWSFGILLTEIVTHGRIPYPGMT 475
+I SD+W+ G + E+ + G P+ G T
Sbjct: 536 PSIMSDLWALGCVFYEMFS-GHPPFLGET 453
>17975
Length = 449
Score = 42.0 bits (97), Expect = 7e-04, Method: Composition-based stats.
Identities = 38/153 (24%), Positives = 63/153 (41%), Gaps = 5/153 (3%)
Frame = +3
Query: 269 KVAVKSL---KQGSMSPDAFLAEANLMKQLQHQRLVRLYAVV-TQEPIYIITEYMENDTL 324
KVAVK + K +S E MK +QH +VRLY V+ TQ +Y+I E + +
Sbjct: 48 KVAVKVIDKTKLDEVSRSHLFQEVRCMKLVQHPNVVRLYEVIDTQTKLYLILELGDGGDM 227
Query: 325 LDSQLEEKGLGASPWGNLGQQLLLLPTGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAF 384
D + G G++ + K QI E +++
Sbjct: 228 YDYIMRHSG-----------------------------GLEEKLAK--RYFRQIVEAISY 314
Query: 385 IEERNYIHRDLRAANILVSDTLS-CKIADFGLA 416
+ + +HRDL+ N++ + K+ DFG +
Sbjct: 315 CHKLHVVHRDLKPENVVFFEKPGLVKLTDFGFS 413
>11185
Length = 473
Score = 41.6 bits (96), Expect = 7e-04, Method: Compositional matrix adjust.
Identities = 31/133 (23%), Positives = 56/133 (42%), Gaps = 21/133 (15%)
Frame = +1
Query: 373 DMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNE-----YTAR 427
D + G+ +I + DLR + +L+ + K ADFGL+++ +N A
Sbjct: 13 DFGIHLVTGLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAE 192
Query: 428 EGAKFPIK----------------WTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPY 471
G ++ I+ + APE +I SD+W+ G + E+ + R+
Sbjct: 193 AGDQWNIQSAEEMMKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSGSRL-- 366
Query: 472 PGMTNPEVIQNLE 484
+PE + LE
Sbjct: 367 SAKPSPEFLNLLE 405
>21433
Length = 590
Score = 41.6 bits (96), Expect = 7e-04, Method: Compositional matrix adjust.
Identities = 25/89 (28%), Positives = 41/89 (46%)
Frame = +2
Query: 377 QIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKW 436
Q++ + + R IHRD++ N+L+ KIADFG + + T G + +
Sbjct: 191 QLSSALEYCHYRKVIHRDIKPENLLLGLKGDLKIADFGWSVHAPSSRRTTMCGT---LDY 361
Query: 437 TAPEAINYGTFTIKSDVWSFGILLTEIVT 465
PE + T D+WS G+L E +
Sbjct: 362 LPPEMVEGKTHDENVDLWSLGVLCYEFLV 448
>13066
Length = 551
Score = 41.6 bits (96), Expect = 7e-04, Method: Compositional matrix adjust.
Identities = 25/84 (29%), Positives = 39/84 (46%), Gaps = 3/84 (3%)
Frame = +3
Query: 377 QIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGL--ARLIEDNEYTAREGAKFPI 434
Q+ + ++ + HRDL+ NIL+S + K+ADFG A + E E
Sbjct: 300 QMTTALNYLHSYDVAHRDLKCENILLSSHFNVKLADFGFACACITESGEKYMSRTYCGSA 479
Query: 435 KWTAPEAINYGTFTIK-SDVWSFG 457
+ APE + + K +D WS G
Sbjct: 480 AYAAPEIVYGAPYAPKVADAWSLG 551
>03240
Length = 1683
Score = 41.6 bits (96), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 64/314 (20%), Positives = 121/314 (38%), Gaps = 55/314 (17%)
Frame = -3
Query: 248 VERLGAGQFGEVWMGYYNGHTKV-AVKSLKQGSM----SPDAFLAEANLMKQLQHQRLVR 302
++ LG G FGEV + N + A+K+L++ + AE +++ + ++ +V+
Sbjct: 1276 IKTLGVGAFGEVSLCRKNDTGMLYAMKTLRKSDVLKRNQVAHVKAERDILAEADNEWVVK 1097
Query: 303 LY-AVVTQEPIYIITEYMENDTLLDSQLEEKGLGASPWGNLGQQLLLLPTGSLVDFLKTP 361
LY + +Y + +Y +P G L+ L
Sbjct: 1096 LYYSFQDHNYLYFVMDY------------------------------VPGGDLMGLLIRM 1007
Query: 362 SGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLA---RL 418
+ + + A++ + + + +IHRD++ NIL+ K+ DFGL R
Sbjct: 1006 EILDEPLARFY--VAELVQAIESVHRMGFIHRDIKPDNILIDRNGHIKLTDFGLCTGFRW 833
Query: 419 IEDNEYTAREGAKF---------------------PIK-------------------WTA 438
+++Y R+G P++ + A
Sbjct: 832 THNSKYYQRDGTHARQDSMEVKCQLDEQCQCEILKPLERRRKREQRCLAHSLVGTPNYIA 653
Query: 439 PEAIN-YGTFTIKSDVWSFGILLTEIVTHGRIPY----PGMTNPEVIQNLERGYRMVRPD 493
PE ++ G +T D WS G++L E++ G P+ P T +VI N + ++ R
Sbjct: 652 PEVLSRLGGYTSVCDWWSVGVILFEMLV-GHPPFYANTPAETQYKVI-NWKDMLKIPRES 479
Query: 494 NCPEELYQL-MRLC 506
N + L +RLC
Sbjct: 478 NLSQPAKDLILRLC 437
>12786
Length = 460
Score = 40.4 bits (93), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 30/108 (27%), Positives = 52/108 (48%), Gaps = 22/108 (20%)
Frame = -3
Query: 391 IHRDLRAAN-ILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPI-KWTAPEAINYGT-- 446
IH DL+ AN +LV+ L K+ DFG+A ++ ++ + + ++ + +PEAI
Sbjct: 344 IHSDLKPANFMLVAGNL--KLIDFGIANTLQQDKTSVLKDSRVGTPSYMSPEAIMAACDD 171
Query: 447 ------------------FTIKSDVWSFGILLTEIVTHGRIPYPGMTN 476
++SDVWS G +L +V +GR P+ + N
Sbjct: 170 SADDSMEEDGHRTKPKYKVGVRSDVWSLGCILYNMV-YGRTPFQHIKN 30
>18481
Length = 437
Score = 40.0 bits (92), Expect = 0.002, Method: Composition-based stats.
Identities = 20/64 (31%), Positives = 36/64 (56%), Gaps = 3/64 (4%)
Frame = -1
Query: 365 KLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCK---IADFGLARLIED 421
+ T+ +L ++ Q+ + FI ++ +IHRDL+ N L+ C I DFGL++ +D
Sbjct: 209 RFTLKTILMVSDQLLSRLEFIHQKCFIHRDLKPDNFLMGLGRHCHRLYIIDFGLSKRYKD 30
Query: 422 NEYT 425
+ T
Sbjct: 29 TQGT 18
>28638
Length = 1458
Score = 40.0 bits (92), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 31/111 (27%), Positives = 55/111 (49%), Gaps = 4/111 (3%)
Frame = -1
Query: 359 KTPSGIKLTINKLLDMAAQIAEGMAFIE--ERNYIHRDLRAANILVSD--TLSCKIADFG 414
+T G+ L + + A Q+ + F+ E N IH DL+ NIL+ + + KI DFG
Sbjct: 861 QTLEGVSLNLTR--KFAQQLCTALLFLATPEMNIIHCDLKPENILLCNPKRSAIKIVDFG 688
Query: 415 LARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVT 465
+ + Y + ++F + +PE + + + D+WS G +L E+ T
Sbjct: 687 SSCQLGQRIYQYIQ-SRF---YRSPEVLLGVPYDLAIDMWSLGCILVEMHT 547
>17286
Length = 489
Score = 39.7 bits (91), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 18/60 (30%), Positives = 35/60 (58%)
Frame = +3
Query: 57 PASPLQDNLVIALHSYEPSHDGDLGFEKGEQLRILEQSGEWWKAQSLTTGQEGFIPFNFV 116
P + ++ A++ + P DG+LGF++G+ + ++ Q E W S+ G+ G+ P N+V
Sbjct: 3 PTAGVKQPCARAIYDFLPESDGELGFQEGDMITLISQVDENWFEGSV-HGKVGYFPINYV 179
>29243
Length = 1147
Score = 39.7 bits (91), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 29/100 (29%), Positives = 47/100 (47%), Gaps = 2/100 (2%)
Frame = +2
Query: 114 NFVAKANSLEPEPWFFKNLSRKDAERQLLAPGNTHGSFLIRESES--TAGSFSLSVRDFD 171
++V + SLE W+ + R A++ L + G+FLIR + + G SLS++
Sbjct: 269 DYVNEPCSLESYNWYVGIMERPVAQKXLDTCPD--GTFLIRVTNNPLRRGELSLSIK--- 433
Query: 172 QNQGEVVKHYKIRNLDNGGFYISPRITFPGLHELVRHYTN 211
V+H K+ G FY++ F + LV HY N
Sbjct: 434 --YANAVRHIKVNRNPQGRFYLADGRYFDNIQSLVDHYEN 547
>32264
Length = 287
Score = 39.3 bits (90), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 18/45 (40%), Positives = 27/45 (60%)
Frame = +1
Query: 483 LERGYRMVRPDNCPEELYQLMRLCWKERPEDRPTFDYLRSVLEDF 527
+E GYR+ + P+ +Y+LM CW+ PE RP F L + L+D
Sbjct: 1 IEDGYRLQQNPQTPDSVYKLMLRCWEYVPEKRPHFKELYTSLKDI 135
>16708
Length = 1397
Score = 38.9 bits (89), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 16/45 (35%), Positives = 27/45 (60%)
Frame = -1
Query: 374 MAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARL 418
+A Q + I E +H D++A N+LV +CK+ D+G+A+L
Sbjct: 1079 IAGQXVCALEHIHELGVVHMDVKADNVLVDAHGNCKLTDYGIAQL 945
>27405
Length = 532
Score = 37.7 bits (86), Expect = 0.011, Method: Composition-based stats.
Identities = 24/80 (30%), Positives = 38/80 (47%)
Frame = -3
Query: 375 AAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPI 434
AA++ G+ + R ++RDL+ ANIL+ + +I+D GLA + A G
Sbjct: 236 AAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGLACDFSKKKPHASVGTH--- 66
Query: 435 KWTAPEAINYGTFTIKSDVW 454
+ APE + G S W
Sbjct: 65 GYMAPEVLMKGQAYDSSADW 6
>27287
Length = 514
Score = 37.0 bits (84), Expect = 0.019, Method: Compositional matrix adjust.
Identities = 15/43 (34%), Positives = 24/43 (55%)
Frame = -2
Query: 489 MVRPDNCPEELYQLMRLCWKERPEDRPTFDYLRSVLEDFFTAT 531
M +P E++ +M CW+E P DRP+F L L+ T++
Sbjct: 513 MKKPPYASSEMFGIMHSCWQEDPNDRPSFSRLVQELDKMLTSS 385
>21210
Length = 518
Score = 36.6 bits (83), Expect = 0.025, Method: Compositional matrix adjust.
Identities = 25/85 (29%), Positives = 42/85 (49%), Gaps = 3/85 (3%)
Frame = +3
Query: 439 PEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNP-EVIQNLERGYRMVRPDN--C 495
P A ++G + ++SDVWS GI L E+ T GR PY + + +Q + RG P +
Sbjct: 42 PRASSHG-YDVRSDVWSLGITLMELAT-GRFPYRKWVSIFDQLQQVVRGVAPCLPHDGAF 215
Query: 496 PEELYQLMRLCWKERPEDRPTFDYL 520
+ + C + + RP ++ L
Sbjct: 216 SHDFVNFVNKCLTKDEKQRPKYNKL 290
>37602
Length = 804
Score = 36.2 bits (82), Expect = 0.033, Method: Compositional matrix adjust.
Identities = 15/48 (31%), Positives = 30/48 (62%)
Frame = -1
Query: 366 LTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADF 413
LT ++ + + +G+ ++ R +HRD++ ANIL+++ K+ADF
Sbjct: 228 LTEPQIAFVCRETLKGLHYLHRRGKMHRDIKGANILLTEEGDVKLADF 85
>32000
Length = 644
Score = 36.2 bits (82), Expect = 0.033, Method: Compositional matrix adjust.
Identities = 30/97 (30%), Positives = 48/97 (49%), Gaps = 3/97 (3%)
Frame = -1
Query: 405 TLSCKIADFGLARL--IEDNEYTAREGAKFPIKWTAPEAINYGTF-TIKSDVWSFGILLT 461
T KIADFGLAR+ + YT + + APE + F ++ D+WS G +
Sbjct: 581 TAKMKIADFGLARVFGLPVRTYTHEV---ITLWYRAPEILLGCRFYSVPVDIWSLGCIFV 411
Query: 462 EIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDNCPEE 498
E++T R +PG + +++ YR+ R P+E
Sbjct: 410 EMMTR-RALFPGDS------EIDQLYRIFRTLGTPDE 321
>07933
Length = 728
Score = 35.4 bits (80), Expect = 0.051, Method: Compositional matrix adjust.
Identities = 14/29 (48%), Positives = 16/29 (55%)
Frame = +3
Query: 492 PDNCPEELYQLMRLCWKERPEDRPTFDYL 520
P+ CP LY +M CW P RPTF L
Sbjct: 3 PNYCPNLLYNIMMQCWSAEPSARPTFHKL 89
>38046
Length = 446
Score = 34.7 bits (78), Expect = 0.11, Method: Composition-based stats.
Identities = 14/25 (56%), Positives = 20/25 (80%)
Frame = -1
Query: 378 IAEGMAFIEERNYIHRDLRAANILV 402
IA+ MA++E+ N+IHR+L NILV
Sbjct: 98 IADAMAYMEKENFIHRNLGDRNILV 24
>20559
Length = 430
Score = 34.3 bits (77), Expect = 0.12, Method: Composition-based stats.
Identities = 21/67 (31%), Positives = 37/67 (55%), Gaps = 4/67 (5%)
Frame = -2
Query: 248 VERLGAGQFGEVWMGY-YNGHTKVAVKSLK---QGSMSPDAFLAEANLMKQLQHQRLVRL 303
+E++G G +G V+ H VA+K ++ P + L E L+K+L+H+ +VRL
Sbjct: 360 LEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHRNIVRL 181
Query: 304 YAVVTQE 310
+ V+ E
Sbjct: 180 HDVLHSE 160
>29590
Length = 320
Score = 33.5 bits (75), Expect = 0.20, Method: Composition-based stats.
Identities = 14/41 (34%), Positives = 27/41 (65%)
Frame = +3
Query: 436 WTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTN 476
+ APE ++Y +I++D+WS G+L ++T P+ G+T+
Sbjct: 72 YVAPEVLDYEPLSIQTDMWSLGVLSYVMLTACS-PFVGITS 191
>11228
Length = 2155
Score = 33.1 bits (74), Expect = 0.31, Method: Compositional matrix adjust.
Identities = 20/40 (50%), Positives = 25/40 (62%)
Frame = -1
Query: 127 WFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLS 166
W+ L R AE +LL + GS+L+RESES GSF LS
Sbjct: 1972 WYHGRLGRAGAE-ELLRDQDA-GSYLVRESESKLGSFVLS 1859
>37260
Length = 401
Score = 32.7 bits (73), Expect = 0.41, Method: Composition-based stats.
Identities = 19/69 (27%), Positives = 35/69 (50%)
Frame = -1
Query: 114 NFVAKANSLEPEPWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLSVRDFDQN 173
+F+ L+ W++ LS ++AE +L+ GSFL+R+S + SLS +
Sbjct: 221 DFLESMKQLKDCGWYWGPLSYEEAESKLM--DKRDGSFLVRDSSNENYILSLSFKSMGHV 48
Query: 174 QGEVVKHYK 182
++H+K
Sbjct: 47 HHTRIEHHK 21
>15741
Length = 402
Score = 32.3 bits (72), Expect = 0.56, Method: Composition-based stats.
Identities = 14/42 (33%), Positives = 20/42 (47%)
Frame = -3
Query: 360 TPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANIL 401
T + LT A +A GMA + +HRD+ A N+L
Sbjct: 127 TSTANDLTARDFFSFALHVARGMAHVANNKIVHRDVAARNVL 2
>13664
Length = 507
Score = 32.0 bits (71), Expect = 0.72, Method: Composition-based stats.
Identities = 16/56 (28%), Positives = 27/56 (48%)
Frame = +2
Query: 55 NPPASPLQDNLVIALHSYEPSHDGDLGFEKGEQLRILEQSGEWWKAQSLTTGQEGF 110
+P S + V+AL+ Y+ +L G+ + +L + E W L GQ+GF
Sbjct: 338 SPLGSTRKPKKVVALYDYKAQRSDELTILSGDVIMLLHKDSESWWMGELLDGQQGF 505
>36481
Length = 806
Score = 31.6 bits (70), Expect = 0.91, Method: Compositional matrix adjust.
Identities = 17/53 (32%), Positives = 27/53 (50%)
Frame = +2
Query: 353 SLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDT 405
S+ DFLK S I ++ ++ Q+ + F+ E H DL+ NIL D+
Sbjct: 623 SVFDFLKDNSYGAYPIEQVRHISYQLCYAVNFLHENQLTHTDLKPENILFVDS 781
>20131
Length = 574
Score = 30.8 bits (68), Expect = 1.4, Method: Compositional matrix adjust.
Identities = 15/53 (28%), Positives = 28/53 (52%), Gaps = 1/53 (1%)
Frame = -2
Query: 67 IALHSYEPSHDGDLGFEKGEQLRILEQSGEWWKAQSLTTGQE-GFIPFNFVAK 118
+A++SY DL F +G+ + + ++ +WW T G++ G P +V K
Sbjct: 471 VAMYSYVSGETADLTFNEGDMILVTKKDEDWWTG---TLGEKTGMFPSTYVKK 322
>06462
Length = 1511
Score = 30.8 bits (68), Expect = 1.4, Method: Compositional matrix adjust.
Identities = 30/116 (25%), Positives = 48/116 (41%), Gaps = 6/116 (5%)
Frame = +1
Query: 125 EPWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLSVRDFDQNQGEVVKHYKIR 184
E W+ +SR++AE+ L G FL+RES F LS ++ G+ + +
Sbjct: 1090 ELWYHGKMSRREAEKLL----GKDGDFLVRESGHNXSQFVLS----GKHHGQFI---HLL 1236
Query: 185 NLDNGGFYISPRITFPGLHELVRHYTN-----ASDGLCTRLSRPCQTQKPQ-KPWW 234
+D G + F + LV ++ + S G L RP P +P W
Sbjct: 1237 LVDPDGIVRTKDYIFDNISHLVSYHCHHGMPIVSHGSQLTLLRPINVSVPAYRP*W 1404
>32357
Length = 625
Score = 30.8 bits (68), Expect = 1.4, Method: Compositional matrix adjust.
Identities = 17/52 (32%), Positives = 33/52 (63%), Gaps = 1/52 (1%)
Frame = -2
Query: 246 KLVERLGAGQFGEVWMGYYN-GHTKVAVKSLKQGSMSPDAFLAEANLMKQLQ 296
+L++++G+G FGE+++G +N +VAVK + + P + E+ L + LQ
Sbjct: 429 RLMKKIGSGSFGEIYLGVHNTSGEEVAVKLELKNAKHPQLYY-ESKLYRVLQ 277
>17516
Length = 453
Score = 29.3 bits (64), Expect = 4.5, Method: Compositional matrix adjust.
Identities = 27/104 (25%), Positives = 50/104 (48%), Gaps = 7/104 (6%)
Frame = -3
Query: 436 WTAPEAI-NYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRM-VRPD 493
+ APE + G + +K+DV+S I+L E+ +G+ +++ + LE + +RP
Sbjct: 421 YMAPEVLLQKGQYDMKADVYSLAIILWEL-WYGQDAADHISS-HLFGRLEDAVQAGLRPS 248
Query: 494 ---NC--PEELYQLMRLCWKERPEDRPTFDYLRSVLEDFFTATE 532
C P++ +L++ W+ RPT EDF T+
Sbjct: 247 VTMTCKPPDDWLKLLQSGWEFHASKRPTSRDAAEFFEDFLERTK 116
>25100
Length = 699
Score = 28.9 bits (63), Expect = 5.6, Method: Compositional matrix adjust.
Identities = 11/38 (28%), Positives = 19/38 (50%)
Frame = +3
Query: 197 ITFPGLHELVRHYTNASDGLCTRLSRPCQTQKPQKPWW 234
+T+ + L+ +T+ L + SR C+ K K WW
Sbjct: 150 LTYCSSYILIHMHTDTHKDLFLKFSRKCRENKADKIWW 263
>18050
Length = 448
Score = 28.5 bits (62), Expect = 6.3, Method: Compositional matrix adjust.
Identities = 16/57 (28%), Positives = 29/57 (50%), Gaps = 1/57 (1%)
Frame = +3
Query: 66 VIALHSYEPSHDGDLGFEKGEQLRILEQSGE-WWKAQSLTTGQEGFIPFNFVAKANS 121
VIA HSYE L E G+ + + + + W++ + + G G+ P ++ + NS
Sbjct: 24 VIAKHSYESDEPDVLQLELGDVVNVSRKLPDGWYQGERIRDGAVGWFPGSYTEELNS 194
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000306330 | hsapiens_gene_ensembl | 14-3-3 protein
gamma (Protein kinase C inhibitor protein 1) (KCIP-1).
[Source:Uniprot/SWISSPROT;Acc:P61981]
(247 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
12344 283 5e-77
13465 181 3e-46
33715 168 2e-42
17028 127 5e-30
15092 121 3e-28
27988 71 1e-20
>12344
Length = 1658
Score = 283 bits (723), Expect = 5e-77, Method: Compositional matrix adjust.
Identities = 146/235 (62%), Positives = 178/235 (75%)
Frame = +2
Query: 1 MVDREQLVQKARLAEQAERYDDMAAAMKNVTELNEPLSNEERNLLSVAYKNVVGARRSSW 60
M DRE V +A+ +AERYD+M MK V ++ L+ EERNLLSVAYKNV+GARR+SW
Sbjct: 56 MGDREDQVYQAKQLNRAERYDEMVKFMKIVACMDVELTVEERNLLSVAYKNVIGARRASW 235
Query: 61 RVISSIEQKTSADGNEKKIEMVRAYREKIEKELEAVCQDVLSLLDNYLIKNCSETQYESK 120
R++SS+EQK D E K + + YR KIEKEL+ +C+DVL +L+ +LI N + ESK
Sbjct: 236 RIVSSLEQKE--DKCEDKKAINKEYRMKIEKELKDICEDVLDILEKHLIVNANTG--ESK 403
Query: 121 VFYLKMKGDYYRYLAEVATGEKRATVVESSEKAYSEAHEISKEHMQPTHPIRLGLALNYS 180
VFY KMKGDY+RYLAE A G R E+S AY A +I+ + PTHPIRLGLALN+S
Sbjct: 404 VFYYKMKGDYHRYLAEFAVGNDRKEAAENSLVAYKAASDIAMIELAPTHPIRLGLALNFS 583
Query: 181 VFYYEIQNAPEQACHLAKTAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTS 235
VFYYEI N+P++AC LAK AFDDAIAELDTL+E+SYKDSTLIMQLLRDNLTLWTS
Sbjct: 584 VFYYEILNSPDRACRLAKAAFDDAIAELDTLSEESYKDSTLIMQLLRDNLTLWTS 748
>13465
Length = 596
Score = 181 bits (459), Expect = 3e-46, Method: Compositional matrix adjust.
Identities = 90/154 (58%), Positives = 114/154 (74%)
Frame = +2
Query: 1 MVDREQLVQKARLAEQAERYDDMAAAMKNVTELNEPLSNEERNLLSVAYKNVVGARRSSW 60
M DR+ V +A+LAEQAERYD+M AMK V + L+ EERNLLSVAYKNV+GARR+SW
Sbjct: 110 MTDRDDFVYQAKLAEQAERYDEMVEAMKKVASMGNDLTVEERNLLSVAYKNVIGARRASW 289
Query: 61 RVISSIEQKTSADGNEKKIEMVRAYREKIEKELEAVCQDVLSLLDNYLIKNCSETQYESK 120
R++SS+EQK + K +M + YR++IE EL+ +C+DVL ++D++LI S TQ ESK
Sbjct: 290 RIVSSVEQKDLDKPDPDKGKMTKGYRQQIETELKQICEDVLKIIDDHLIP--STTQGESK 463
Query: 121 VFYLKMKGDYYRYLAEVATGEKRATVVESSEKAY 154
VFY KMKGDYYRYLAE ATG+ R ESS AY
Sbjct: 464 VFYYKMKGDYYRYLAEFATGDPRKEAAESSLVAY 565
>33715
Length = 434
Score = 168 bits (425), Expect = 2e-42, Method: Compositional matrix adjust.
Identities = 79/112 (70%), Positives = 94/112 (83%)
Frame = -1
Query: 124 LKMKGDYYRYLAEVATGEKRATVVESSEKAYSEAHEISKEHMQPTHPIRLGLALNYSVFY 183
LKMKGDYYRYL+EV+ GE+R V S +AY EA +++KE + THPIRLGLALN+SVF+
Sbjct: 374 LKMKGDYYRYLSEVSQGEQRKENVGKSMEAYKEATDMAKERLSSTHPIRLGLALNFSVFH 195
Query: 184 YEIQNAPEQACHLAKTAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTS 235
YEI+N P++AC LAK AFD+AI LD LNE+SYKDSTLIMQLLRDNLTLWTS
Sbjct: 194 YEIKNCPDEACRLAKIAFDEAIQCLDQLNEESYKDSTLIMQLLRDNLTLWTS 39
>17028
Length = 1078
Score = 127 bits (318), Expect = 5e-30, Method: Compositional matrix adjust.
Identities = 61/90 (67%), Positives = 74/90 (82%), Gaps = 1/90 (1%)
Frame = +1
Query: 147 VESSEKAYSEAHEISKEHMQPTHPIRLGLALNYSVFYYEIQNAPEQACHLAKTAFDDAIA 206
V +++AY++A E++K+ M PTHP RLGLALNYSVFYYEI N+ ++AC LAKTAFD+AI
Sbjct: 37 VTKAQEAYNKAMEVAKQSMAPTHPNRLGLALNYSVFYYEILNSQDKACDLAKTAFDEAIQ 216
Query: 207 ELDTLNE-DSYKDSTLIMQLLRDNLTLWTS 235
E+D E D KDSTLIMQLLRDNLTLWTS
Sbjct: 217 EMDQCGERDDCKDSTLIMQLLRDNLTLWTS 306
>15092
Length = 692
Score = 121 bits (303), Expect = 3e-28, Method: Compositional matrix adjust.
Identities = 67/112 (59%), Positives = 83/112 (74%), Gaps = 8/112 (7%)
Frame = +3
Query: 4 REQLVQKARLAEQAERYDDMAAAM-KNVTE-------LNEPLSNEERNLLSVAYKNVVGA 55
+E+ V A++AEQAERYDDMA +M K V E + L NEERNLLSVAYKNVVGA
Sbjct: 231 KERQVHAAKIAEQAERYDDMAESMHKCVVEGYSANGDKSSTLDNEERNLLSVAYKNVVGA 410
Query: 56 RRSSWRVISSIEQKTSADGNEKKIEMVRAYREKIEKELEAVCQDVLSLLDNY 107
RRS+WRVISSIEQKT + N+KK+EM + YREK+EKEL+ +C VL + +Y
Sbjct: 411 RRSAWRVISSIEQKT--ENNDKKLEMAKKYREKVEKELKEICTQVLVRIHHY 560
>27988
Length = 448
Score = 70.9 bits (172), Expect(2) = 1e-20, Method: Compositional matrix adjust.
Identities = 38/60 (63%), Positives = 45/60 (75%)
Frame = +3
Query: 44 LLSVAYKNVVGARRSSWRVISSIEQKTSADGNEKKIEMVRAYREKIEKELEAVCQDVLSL 103
L SVAYKNVVGARRSSWRVI IEQK A+ +K E RA+R+ +EKEL+A C +VL L
Sbjct: 276 LFSVAYKNVVGARRSSWRVICMIEQK--AETQPRK-EKARAFRKDVEKELDATCNEVLKL 446
Score = 46.2 bits (108), Expect(2) = 1e-20, Method: Compositional matrix adjust.
Identities = 23/42 (54%), Positives = 30/42 (71%)
Frame = +2
Query: 1 MVDREQLVQKARLAEQAERYDDMAAAMKNVTELNEPLSNEER 42
+ + + L+ A+LAEQAERYDDMA AMK VTE ++ L E R
Sbjct: 146 LTESKDLISFAKLAEQAERYDDMAKAMKKVTENDKTLMQESR 271
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000352348 | hsapiens_gene_ensembl | Cytoplasmic
dynein 1 intermediate chain 1 (Dynein intermediate chain 1, cytosolic)
(DH IC-1) (Cytoplasmic dynein intermediate chain 1).
[Source:Uniprot/SWISSPROT;Acc:O14576]
(608 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
20271 283 1e-76
14105 168 5e-42
12841 121 8e-28
07741 57 2e-08
20662 49 5e-06
08355 49 7e-06
03387 45 6e-05
13278 40 0.004
01598 38 0.012
02960 36 0.050
15972 35 0.092
13335 34 0.15
27475 33 0.30
01768 32 0.74
05393 32 0.92
27465 31 1.3
00561 28 7.8
37180 28 8.7
>20271
Length = 567
Score = 283 bits (724), Expect = 1e-76, Method: Compositional matrix adjust.
Identities = 130/188 (69%), Positives = 154/188 (81%)
Frame = -1
Query: 353 HPVYCVNVVGTQNAHNLITVSTDGKMCSWSLDMLSTPQESMELVYNKSKPVAVTGMAFPT 412
HPVYC+ VVGTQNAHNLI+VS DGK+CSWSLDMLS PQ+SMEL + +SK VA T +F +
Sbjct: 567 HPVYCITVVGTQNAHNLISVSNDGKLCSWSLDMLSQPQDSMELQHKQSKSVAATCFSFLS 388
Query: 413 GDVNNFVVGSEEGTVYTACRHGSKAGIGEVFEGHQGPVTGINCHMAVGPIDFSHLFVTSS 472
GD NNF+VGSEE VY+A RHGSKAGI E +EGHQGP+T I+ H A G IDFS F+T+S
Sbjct: 387 GDANNFIVGSEECLVYSASRHGSKAGINEAYEGHQGPITAIDTHHAAGQIDFSPFFLTAS 208
Query: 473 FDWTVKLWTTKHNKPLYSFEDNADYVYDVMWSPVHPALFACVDGMGRLDLWNLNNDTEVP 532
FDWTVKLW K K + SFEDN+DYV DV WSP +PALF+CVD MGRLDLW+LN++TEVP
Sbjct: 207 FDWTVKLWNIKEQKYVCSFEDNSDYVSDVQWSPTNPALFSCVDIMGRLDLWHLNHETEVP 28
Query: 533 TASVAIEG 540
TASV ++G
Sbjct: 27 TASVVVDG 4
>14105
Length = 429
Score = 168 bits (426), Expect = 5e-42, Method: Compositional matrix adjust.
Identities = 78/120 (65%), Positives = 93/120 (77%), Gaps = 1/120 (0%)
Frame = +3
Query: 479 LWTTKHNKPLYSFEDNADYVYDVMWSPVHPALFACVDGMGRLDLWNLNNDTEVPTASVAI 538
LW+ K KPLYSFEDN+DYV DV WSPVHPALFA VDG GRLDLWNLN DTEVPTAS+ +
Sbjct: 3 LWSLKDTKPLYSFEDNSDYVMDVAWSPVHPALFAAVDGSGRLDLWNLNQDTEVPTASIVV 182
Query: 539 EGASALNRVRWAQAGKEVAVGDSEGRIWVYDVGE-LAVPHNDEWTRFARTLVEIRANRAD 597
+GA ALNRV W +G V +GD G+++VYDV E LA+P DEW+RF TL E++ N+ D
Sbjct: 183 DGAPALNRVSWTPSGLHVTIGDESGKLYVYDVAEHLALPTRDEWSRFNATLNELKMNQND 362
Score = 29.6 bits (65), Expect = 3.7, Method: Compositional matrix adjust.
Identities = 17/52 (32%), Positives = 22/52 (42%), Gaps = 1/52 (1%)
Frame = +3
Query: 290 KFKKTTPEYVFHCQSS-VMSVCFARFHPNLVVGGTYSGQIVLWDNRSHRRTP 340
K T P Y F S VM V ++ HP L SG++ LW+ P
Sbjct: 9 SLKDTKPLYSFEDNSDYVMDVAWSPVHPALFAAVDGSGRLDLWNLNQDTEVP 164
>12841
Length = 1364
Score = 121 bits (304), Expect = 8e-28, Method: Compositional matrix adjust.
Identities = 84/329 (25%), Positives = 148/329 (44%), Gaps = 25/329 (7%)
Frame = +1
Query: 248 SKHRVVTCMDWSLQYPELMVASYNNNEDAPHEPDGVALVWNMKFKKTTPEYVFHCQSSVM 307
+K R V+C+ W+ P+L+ Y D ++ G+ W++K PE V+ V
Sbjct: 394 TKGRNVSCLAWNKSNPDLVAVGYGQF-DFTNQKSGLICCWSLK-NPEYPERVYTSTHGVT 567
Query: 308 SVCFARFHPNLVVGGTYSGQIVLWDNRSHRRTPVQRTPLSAAAHTHPVYCVNVV------ 361
S+ F+ + N++ G Y G + +++ RS P+ + H PV+ + +
Sbjct: 568 SLDFSVANANILAAGYYDGGVAIYNVRSTSDEPILDNQETHGKHLGPVWQIQWIEKERGS 747
Query: 362 GTQNAHNLITVSTDGKMCSWSLDMLSTPQESMELVYNKSKPVAVTGMA------------ 409
G + A LI++STDG++ WS+ ES ++ K P + G A
Sbjct: 748 GEERAEVLISISTDGRVTQWSI---RKGFESNNIMRLKKLPTRMAGKAREKKGEAFISRH 918
Query: 410 -------FPTGDVNNFVVGSEEGTVYTACRHGSKAGIGEVFEGHQGPVTGINCHMAVGPI 462
F + D+N ++ G+EEG ++ C E + GH PV H+ P
Sbjct: 919 AGGLCFDFHSRDLNVYLAGTEEGYIH-KCSCSYNEQYLETYSGHTAPVY----HIRWSPF 1083
Query: 463 DFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMWSPVHPALFACVDGMGRLDL 522
S +F++ S DW+++LW P+ +F + V+DV WSP +FACV G +++
Sbjct: 1084-VSDIFLSCSADWSIRLWHQDRTTPILTFHSSTKTVHDVCWSPRSSTVFACVH-EGAVEV 1257
Query: 523 WNLNNDTEVPTASVAIEGASALNRVRWAQ 551
W+L T ++ + L V + +
Sbjct: 1258WDLAQSTLDAVITITPTSGAKLTSVTFGK 1344
>07741
Length = 2119
Score = 57.0 bits (136), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 44/165 (26%), Positives = 77/165 (46%), Gaps = 17/165 (10%)
Frame = +1
Query: 418 FVVGSEEGTVYTACRHGSKAGIGEVFEGHQGPVTGINCHMAVGPIDFSH----LFVTSSF 473
F+VG+EEG V+ C + + + H +MAV + ++H ++ T S
Sbjct: 157 FLVGTEEGKVH-VCSKAYTSHFIDTLDSH---------NMAVYKVAWNHYHPKIYATCSA 306
Query: 474 DWTVKLW-----------TTKHNKPLYSFEDNADYVYDVMWSPVHPALFACVDGMGRLDL 522
DW VK+W + KPL+SF+ N + V DV W+P +FA V G++ +
Sbjct: 307 DWNVKIWENGGKPTDTGXDSLSRKPLFSFDLN-NSVGDVAWAPYSSTVFAAVTADGKVCV 483
Query: 523 WNLNNDTEVPTAS--VAIEGASALNRVRWAQAGKEVAVGDSEGRI 565
++L+ + P VA + + L + + + + VGD G +
Sbjct: 484 YDLSVNKYEPLCEQMVAQKKKTKLTHIEFNPSYPILIVGDDRGNV 618
Score = 28.1 bits (61), Expect = 10.0, Method: Compositional matrix adjust.
Identities = 20/81 (24%), Positives = 37/81 (45%), Gaps = 8/81 (9%)
Frame = +1
Query: 498 VYDVMWSPVHPALFACVDGMGRLDLW-NLNNDTEVPTASV------AIEGASALNRVRWA 550
VY V W+ HP ++A + +W N T+ S+ + + +++ V WA
Sbjct: 250 VYKVAWNHYHPKIYATCSADWNVKIWENGGKPTDTGXDSLSRKPLFSFDLNNSVGDVAWA 429
Query: 551 QAGKEV-AVGDSEGRIWVYDV 570
V A ++G++ VYD+
Sbjct: 430 PYSSTVFAAVTADGKVCVYDL 492
>20662
Length = 1220
Score = 49.3 bits (116), Expect = 5e-06, Method: Compositional matrix adjust.
Identities = 34/112 (30%), Positives = 57/112 (50%), Gaps = 4/112 (3%)
Frame = +2
Query: 463 DFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMWSPVHPALFACVDGMGRLDL 522
D SH ++++S+D +K+W T LY++ ++D V+DV P PALF G++ L
Sbjct: 419 DXSH-YLSASYDHGIKVWNTDLTS-LYTYRAHSDIVWDVQCHPTEPALFLSCSQDGKIVL 592
Query: 523 WNLNND---TEVPTASVAIEGASALNRVRWAQAGKEV-AVGDSEGRIWVYDV 570
W++ T +P S + V+W + + AVGD G + V D+
Sbjct: 593 WDVRESKPATCLPKCSSGFKPTC----VQWQPNARNMYAVGDEGGHVSVQDL 736
>08355
Length = 498
Score = 48.9 bits (115), Expect = 7e-06, Method: Composition-based stats.
Identities = 43/175 (24%), Positives = 73/175 (41%), Gaps = 18/175 (10%)
Frame = -1
Query: 324 YSGQIVLWDNRSHRRTPVQRTPLSAAAHTHPVYCV--NVVGTQNAHNLITVSTDGKMCSW 381
Y G + L++ PVQR HT PV+ V + N N ++S+DG++ W
Sbjct: 495 YDGSVALFNTIEKHNNPVQRCTADNGKHTDPVWQVRWQKDDSDNNMNFFSISSDGRIVHW 316
Query: 382 S----------LDMLSTPQESMELVYNKSKPVAVTGMAFPTGDVNN--FVVGSEEGTVYT 429
+ + L+ P E V G AF + F+VG+EEG ++
Sbjct: 315 TIVKNEMIYQDIIQLTIPGPPAEGPDGIRMEVTGCGTAFDFHKHKDYLFLVGTEEGKMHV 136
Query: 430 ACRHGSKAGIGEVFEGHQGPVTGINCHMAVGPIDFS----HLFVTSSFDWTVKLW 480
+ + IG +G +MA+ + ++ +++ T S DW VK+W
Sbjct: 135 CSKAYTSHFIG----------SGDAHNMAIYKVAWNRFHPNVYATCSADWNVKIW 1
>03387
Length = 1891
Score = 45.4 bits (106), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 56/221 (25%), Positives = 95/221 (42%), Gaps = 10/221 (4%)
Frame = +1
Query: 316 PNLVVGGTYSGQIVLWDNRSHRRTP---VQRTP-LSAAAHTHPVYCVNVVGTQNAHNLIT 371
P ++ T S ++++D H P + P L H Y ++ N H L++
Sbjct: 241 PCIIATKTPSSDVLVFDYTKHPSKPDPSGECIPELRLKGHQKEGYGLSWNPNLNGH-LLS 417
Query: 372 VSTDGKMCSWSLDMLSTPQES----MELVYNKSKPVAVTGMAFPTGDVNNF-VVGSEEGT 426
S D +C W D+ ST +ES ++ V V +A+ + F V ++
Sbjct: 418 ASDDHTICLW--DINSTQRESRVVDAHTIFTGHTSV-VEDVAWHLLHESLFGSVADDQKL 588
Query: 427 VYTACRHGSKAGIGEVFEGHQGPVTGINCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNK 486
+ R + + V + H V NC ++ P + T S D TV LW ++ K
Sbjct: 589 MIWDTRSNTTSKPSHVVDAHTAEV---NC-LSFNPYS-EFILATGSADKTVALWDLRNLK 753
Query: 487 -PLYSFEDNADYVYDVMWSPVHPALFACVDGMGRLDLWNLN 526
L+SFE + D ++ V WSP + + A RL +W+L+
Sbjct: 754 LKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLHVWDLS 876
>13278
Length = 870
Score = 39.7 bits (91), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 29/110 (26%), Positives = 51/110 (46%), Gaps = 4/110 (3%)
Frame = +1
Query: 465 SHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMWSPVHPALFACVDGMGRLD--- 521
S + ++SFD TV+LW + L++ + + VY V +SP L + G D
Sbjct: 112 SLILASASFDSTVRLWEVERGLCLHTLTKHQEPVYSVAFSPDGKYLAS-----GSFDKCV 276
Query: 522 -LWNLNNDTEVPTASVAIEGASALNRVRWAQAGKEVAVGDSEGRIWVYDV 570
+WN+ + V + +G + V W G +V S+G ++V D+
Sbjct: 277 HIWNVQTGSLVH----SYKGTGGIFEVCWNHRGDKVGASASDGSVFVLDL 414
>01598
Length = 1545
Score = 38.1 bits (87), Expect = 0.012, Method: Compositional matrix adjust.
Identities = 40/137 (29%), Positives = 57/137 (41%), Gaps = 3/137 (2%)
Frame = +1
Query: 443 FEGHQGPVTGINCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVM 502
+ H PV I A GP S T + D V LW + + + S +VY V
Sbjct: 364 YRPHMRPVFNI---CASGPD--SKTLCTFAQDRQVVLWDLETMEAVASMATLGGHVYCVR 528
Query: 503 WSPVHPALFACVDGMGRLDLWNLNNDTEVPTASVAIEG-ASALNRVRWAQAGKE--VAVG 559
SP+ P A G + WN++N T + +G S + V W KE + G
Sbjct: 529 TSPIDPGRVAVGVGDSMIRTWNMSNKTNPYDVTTLWQGIKSKVTAVAW-HPTKEGWLGFG 705
Query: 560 DSEGRIWVYDVGELAVP 576
+GRI V+DV +P
Sbjct: 706 TDDGRIGVFDVLSHKMP 756
>02960
Length = 1577
Score = 35.8 bits (81), Expect = 0.050, Method: Compositional matrix adjust.
Identities = 57/257 (22%), Positives = 95/257 (36%), Gaps = 33/257 (12%)
Frame = +2
Query: 281 DGVALVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPN--LVVGGTYSGQIVLWDNRSH-- 336
D ALVW + + + C+ SV P+ + G++ + LW +
Sbjct: 680 DQTALVWQWQRETNEVDCRLSCRGHAASVDCVAVSPDSQQMCTGSWDKMLKLWSTDCNVD 859
Query: 337 -----------------RRTPVQRTP-LSAAAHTHPVYCVNVVGTQNAHNLITVSTDGKM 378
+ T R P L+ + H V V + + H ++T S D +
Sbjct: 860 GDQSEDTERPSKKKKSAKSTTQTRVPVLTLSGHAEAVSAVRWL---DPHRVVTSSWDHSL 1030
Query: 379 CSWSL------DMLSTPQESMELVYNKSKPVAVTGMAFPTGDVNNFVVGSEEGTVYTACR 432
W L ++ + +++ Y+ + +TG A D + +V C
Sbjct: 1031RLWDLHTAQQTSLIQGSKAVLDVAYSPLSHMLITGSA----DRHVRLVDPR-------CS 1177
Query: 433 HGSKAGIGEVFEGHQGPVTGINCHMAVGPIDFS----HLFVTSSFDWTVKLWTTKHNKP- 487
G F H G VTG+ D+S HLF++ S+D +KLW T+ K
Sbjct: 1178EGETVKCA--FTSHTGWVTGV---------DWSPTREHLFLSGSYDNVLKLWDTRSPKAT 1324
Query: 488 LYSFEDNADYVYDVMWS 504
LY + D + V WS
Sbjct: 1325LYDMNWHEDRILAVDWS 1375
>15972
Length = 1069
Score = 35.0 bits (79), Expect = 0.092, Method: Compositional matrix adjust.
Identities = 24/83 (28%), Positives = 40/83 (48%)
Frame = +3
Query: 443 FEGHQGPVTGINCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVM 502
F GH+GPV H+AV P L +T S D T++LW + + + + + V
Sbjct: 225 FSGHKGPVR----HLAVHP--SGKLTLTVSQDRTLRLWNNMNGRIAF-ISNMKEAAESVR 383
Query: 503 WSPVHPALFACVDGMGRLDLWNL 525
W+P L+ V LD++++
Sbjct: 384 WAP--GGLYYVVAFRSHLDVYSV 446
>13335
Length = 863
Score = 34.3 bits (77), Expect = 0.15, Method: Compositional matrix adjust.
Identities = 55/234 (23%), Positives = 86/234 (36%), Gaps = 26/234 (11%)
Frame = +1
Query: 285 LVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNL--VVGGTYSGQIVLWDNRSHRRTPVQ 342
+VW++K EY H S + VC +F P+ +V G+ I +W+ Q
Sbjct: 7 IVWDVKTGSIKGEYQ-HASKSSIRVC--KFSPSSSHLVSGSDDDTICMWE------VATQ 159
Query: 343 RTPLSAAAHTHPVYCVNVVGTQNAHNLITVSTDGKMCSWSLDM-------LSTPQESMEL 395
+ S H V + + + N H L++ S +G + W L + +
Sbjct: 160 KLVRSYVGHEDSV--MALAYSPNGHYLVSGSPNGDLYVWDASFGHCRHLTLRVDAHDLGV 333
Query: 396 VYNKSKPVAVTGMA---------FPTGDVNNFV--------VGSEEGTVYTACRHGSKAG 438
+ P T A TG +N + VGS E T+ CR
Sbjct: 334 TCCEFSPTFGTACAENSSTCNLLLATGGKDNLIKLWTFSAQVGSPEVTL--QCR------ 489
Query: 439 IGEVFEGHQGPVTGINCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFE 492
++ GH V MA S L + SFD +V+LW + L+S E
Sbjct: 490 --DILSGHSDLV------MACAFSPSSALLASGSFDKSVRLWDSVKGVALFSIE 627
>27475
Length = 369
Score = 33.1 bits (74), Expect = 0.30, Method: Compositional matrix adjust.
Identities = 25/75 (33%), Positives = 34/75 (45%), Gaps = 1/75 (1%)
Frame = +2
Query: 442 VFEGHQGPVTGINCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKP-LYSFEDNADYVYD 500
F H G VTG++ HLF++ S+D +KLW T+ K LY + D +
Sbjct: 53 AFTSHTGWVTGVDWSPTR-----EHLFLSGSYDNVLKLWDTRSPKATLYDMNWHEDRILA 217
Query: 501 VMWSPVHPALFACVD 515
V WS L VD
Sbjct: 218 VDWSIPELLLSGGVD 262
>01768
Length = 1424
Score = 32.0 bits (71), Expect = 0.74, Method: Compositional matrix adjust.
Identities = 29/120 (24%), Positives = 53/120 (44%), Gaps = 17/120 (14%)
Frame = +3
Query: 424 EGTVYTAC------------RHGSKAGIGEVFEGHQGPVTGINCHMAVGPIDFSHLFVTS 471
EG V+ +C + SKA + V E H + IN + PI+ HL +
Sbjct: 873 EGNVFASCSVDRTLRIWNTQQKPSKANVLTVPEAHSRDINVINWN----PIE-KHLLASG 1037
Query: 472 SFDWTVKLWTTK--HNKPL---YSFEDNADYVYDVMWSPVHPALFACVDGMGRLDLWNLN 526
D +K+W + NKP+ SF+ ++ V + W+P ++ A ++ +W+ +
Sbjct: 1038GDDGIIKIWDLRMFRNKPVSAQASFKLHSQPVTSLEWNPQDSSVLAASGEDDQITIWDFS 1217
Score = 30.8 bits (68), Expect = 1.7, Method: Compositional matrix adjust.
Identities = 26/93 (27%), Positives = 39/93 (41%), Gaps = 2/93 (2%)
Frame = +3
Query: 480 WTTKHNKPLYSFEDNADYVYDVMWSPVHPALFACVDGMGRLDLWNLNNDTEVPTASVAIE 539
WTT+ + S+ + D V DV WSP +FA L +WN E
Sbjct: 804 WTTEKS----SYAAHTDSVEDVQWSPNEGNVFASCSVDRTLRIWNTQQKPSKANVLTVPE 971
Query: 540 GASA-LNRVRWAQAGKE-VAVGDSEGRIWVYDV 570
S +N + W K +A G +G I ++D+
Sbjct: 972 AHSRDINVINWNPIEKHLLASGGDDGIIKIWDL 1070
>05393
Length = 904
Score = 31.6 bits (70), Expect = 0.92, Method: Compositional matrix adjust.
Identities = 24/93 (25%), Positives = 41/93 (44%), Gaps = 7/93 (7%)
Frame = +1
Query: 446 HQGPVTGINCHMA-VGPIDFSH----LFVTSSFDWTVKLWTTKHNKPLYSFEDNADY--V 498
H+ PV + H + V + S L +T+S D T+K+W + +KP + F N +
Sbjct: 187 HEKPVFSVGAHSSCVTGVCLSSQIPGLMITTSEDKTMKVWDIQDDKPTHVFSRNLKMKEL 366
Query: 499 YDVMWSPVHPALFACVDGMGRLDLWNLNNDTEV 531
+ P P +FA G +W++ V
Sbjct: 367 HCTGCCPEAPFVFAVGGGRREPKVWDIRESAAV 465
>27465
Length = 658
Score = 31.2 bits (69), Expect = 1.3, Method: Compositional matrix adjust.
Identities = 29/103 (28%), Positives = 47/103 (45%), Gaps = 2/103 (1%)
Frame = -1
Query: 405 VTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIGEV--FEGHQGPVTGINCHMAVGPI 462
+T +AF ++F+ GS + T C+ A E+ EGH+ V I + P
Sbjct: 352 LTNVAFNKSG-SSFITGSYDRT----CKIWDTASAEELHTLEGHRNVVYAIAFN---NP- 200
Query: 463 DFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMWSP 505
F +T SFD T KLW+T K ++ + + V ++P
Sbjct: 199 -FGDKVITGSFDKTCKLWSTADGKCYHTLRGHTAEIVCVSFNP 74
>00561
Length = 1003
Score = 28.5 bits (62), Expect = 7.8, Method: Compositional matrix adjust.
Identities = 30/89 (33%), Positives = 42/89 (47%), Gaps = 4/89 (4%)
Frame = -3
Query: 443 FEGHQGPVTGINCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFED-NADYVYDV 501
FEGH V ++V + V+ S D T+KLW T ED + D+V V
Sbjct: 752 FEGHTKDV------LSVAFSADNRQIVSGSRDKTIKLWNTLAECKFTIQEDGHTDWVSCV 591
Query: 502 MWSPVH--PALFACVDGMGR-LDLWNLNN 527
+SP H P + +C G R + +WNL N
Sbjct: 590 RFSPNHSNPIIVSC--GWDRTVKVWNLAN 510
>37180
Length = 681
Score = 28.5 bits (62), Expect = 8.7, Method: Compositional matrix adjust.
Identities = 31/112 (27%), Positives = 49/112 (43%), Gaps = 6/112 (5%)
Frame = +1
Query: 441 EVFEGHQGPVTGINCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYD 500
V GH ++ ++ H L VTSS D T +LW + + L + V+
Sbjct: 1 NVLNGHDQELSDVHAHPT------QRLVVTSSKDMTFRLWDFRDSALLVN-------VFQ 141
Query: 501 VMWSPVHPALFACVDGM--GRLD----LWNLNNDTEVPTASVAIEGASALNR 546
PV A+FA D + G D +W++ N P A++ + SA+NR
Sbjct: 142 GHTQPVTSAVFASGDKVVSGSDDRTVRVWDMRN-MRSPIATIRTD--SAVNR 288
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000362665 | hsapiens_gene_ensembl | Proto-oncogene
tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK) (Lymphocyte
cell-specific protein-tyrosine kinase) (LSK) (T cell- specific
protein-tyrosine kinase). [Source:Uniprot/SWISSPROT;Acc:P06239]
(516 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
21808 281 1e-76
06405 245 4e-65
11780 149 4e-56
04852 162 3e-40
09007 147 7e-36
07291 138 4e-33
17300 124 8e-32
20640 124 1e-28
14116 109 2e-24
18996 107 9e-24
17637 105 4e-23
22005 84 5e-23
08294 103 1e-22
07940 100 2e-21
14477 86 3e-17
13305 85 8e-17
01718 83 3e-16
07833 77 1e-14
29581 75 5e-14
17253 73 3e-13
01060 71 1e-12
12721 70 2e-12
13592 70 2e-12
18921 69 3e-12
01707 69 4e-12
14126 68 7e-12
00715 67 2e-11
01966 65 5e-11
14420 65 7e-11
19301 65 7e-11
27546 64 1e-10
18484 63 3e-10
12672 63 3e-10
01756 62 6e-10
04591 61 1e-09
00300 61 1e-09
25550 61 1e-09
07836 59 5e-09
17975 57 2e-08
13066 57 2e-08
31885 57 2e-08
19094 55 6e-08
21079 51 1e-06
30755 51 1e-06
04138 50 3e-06
13212 49 5e-06
09606 49 5e-06
15910 49 6e-06
26711 47 2e-05
35671 47 2e-05
03240 46 4e-05
01392 45 7e-05
19761 45 8e-05
37602 45 9e-05
26560 44 2e-04
27405 42 5e-04
21433 42 7e-04
11185 42 8e-04
12786 40 0.002
28638 40 0.003
18481 40 0.003
32264 39 0.004
16708 39 0.004
17286 39 0.006
29243 38 0.008
27287 37 0.017
21210 37 0.020
32000 36 0.032
07933 35 0.057
38046 35 0.11
29590 34 0.16
11228 33 0.22
37260 33 0.32
36481 33 0.38
15741 32 0.53
06462 31 1.3
13664 31 1.3
20131 31 1.4
17516 29 5.0
30665 28 6.5
18050 28 7.1
>21808
Length = 1011
Score = 281 bits (720), Expect(2) = 1e-76, Method: Compositional matrix adjust.
Identities = 137/223 (61%), Positives = 174/223 (78%), Gaps = 1/223 (0%)
Frame = +1
Query: 271 YNGHTKVAVKSLKQGSMSPDAFLAEANLMKQLQHQRLVRLYAVVTQE-PIYIITEYMENG 329
+N T VA+K+LK G+M P FLAEA +MK+L+H +L++LYAV TQ+ PI+IITE M+NG
Sbjct: 10 WNNTTPVAIKTLKSGTMDPKDFLAEAQIMKKLRHPKLIQLYAVCTQDDPIFIITELMKNG 189
Query: 330 SLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIAD 389
SL++FL+ G L + L+D+ AQIA GMA++E +NYIHRDL A NILVSD + KIAD
Sbjct: 190 SLLEFLQG-KGRVLKLPALIDIGAQIACGMAYLESQNYIHRDLAARNILVSDNNTVKIAD 366
Query: 390 FGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYP 449
FGLAR+I+++EY AR GA+FPIKWTAPEA NY FTIKSDVWSFGILLTE VT+GR+PYP
Sbjct: 367 FGLARVIKEDEYEARVGARFPIKWTAPEAANYNRFTIKSDVWSFGILLTETVTYGRVPYP 546
Query: 450 GMTNPEVIQNLERGYRMVRPDNCPEELYQLMRLCWKERPEDRP 492
GMTN EV+ +E GYRM P CP+ LY +M CW++ +RP
Sbjct: 547 GMTNAEVLHQVEHGYRMPCPPGCPKPLYDIMLECWRKEEMERP 675
Score = 23.9 bits (50), Expect(2) = 1e-76, Method: Compositional matrix adjust.
Identities = 13/29 (44%), Positives = 17/29 (58%)
Frame = +2
Query: 485 KERPEDRPTFDYLRSVLEDFFTATEGQYQ 513
K R D PTF+ L+ LE+FFT Y+
Sbjct: 656 KRRWRD-PTFETLQWKLEEFFTMDSKDYR 739
>06405
Length = 1965
Score = 245 bits (625), Expect = 4e-65, Method: Compositional matrix adjust.
Identities = 117/230 (50%), Positives = 166/230 (72%), Gaps = 1/230 (0%)
Frame = +1
Query: 277 VAVKSLKQGSMSPDAFLAEANLMKQLQHQRLVRLYAVVTQEP-IYIITEYMENGSLVDFL 335
VAVK+LK+ +M+ + FL EA +MK+++H LV+L V T+EP YI+TE+M +G+L+D+L
Sbjct: 343 VAVKTLKEDTMALNDFLEEAAIMKEMKHPNLVQLLGVCTREPPFYIVTEFMPHGNLLDYL 522
Query: 336 KTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARL 395
++ + + L+ MA QIA GMA++E +N+IHRDL A N LV+D+ K+ADFGLARL
Sbjct: 523 RSSTREENGPTALMYMATQIASGMAYLETKNFIHRDLAARNCLVADSNMVKVADFGLARL 702
Query: 396 IEDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPE 455
++D+ YTA GAKFPIKWTAPE + + F+ +SD+W+FG+LL E+ T+G PYPG+ E
Sbjct: 703 MKDDTYTAHIGAKFPIKWTAPEGLAFNRFSTRSDIWAFGVLLWELATYGMSPYPGVELTE 882
Query: 456 VIQNLERGYRMVRPDNCPEELYQLMRLCWKERPEDRPTFDYLRSVLEDFF 505
V LERGYRM RP P ++Y LM CW+ P+DRPTF + +LE+ F
Sbjct: 883 VYHLLERGYRMERPPGTPADVYILMLKCWQWDPKDRPTFKEIHFLLENMF 1032
>11780
Length = 1713
Score = 149 bits (377), Expect(2) = 4e-56, Method: Compositional matrix adjust.
Identities = 106/334 (31%), Positives = 162/334 (48%), Gaps = 54/334 (16%)
Frame = +3
Query: 140 FEKGEQLRILEQSGE--WWKAQSLTTGQEGFIPFNFVA--KANSLEPEPWFFKNLSRKDA 195
F+KG+ L I + + W+KA + G+EG IP N+V K +L PWF ++R+ A
Sbjct: 111 FQKGDLLVIRRATSDRMWYKACD-SNGREGMIPANYVQPRKVVTLHAMPWFHGKITRQQA 287
Query: 196 ERQLLAPGNTHGSFLIRESESTAGSFSLSV----------------------RDFDQNQG 233
E +LL P G FLIRES + G ++L V F +N
Sbjct: 288 E-ELLKP-REDGLFLIRESSNYPGDYTLCVCHLGKVEHYRILYRENQLTIDEEGFFRNLD 461
Query: 234 EVVKHY-------------------------KIRNLDNGGFYISPRITFPGLHELVRHYT 268
E+VKHY ++ +GG+ I+ + G +
Sbjct: 462 ELVKHYLADADGLCTQLTRPVTKQGGNFGTVSLQEFKSGGWVIAXQDLEIGEAIGKGDFG 641
Query: 269 RYYNGHTK---VAVKSLKQGSMSPDAFLAEANLMKQLQHQRLVRLYAVVTQEPIYIITEY 325
Y G + VA+K LK +FL EA++M L+H LVRL VV E I+++TE+
Sbjct: 642 DVYKGMYRGQPVAIKQLKDKDRGEQSFLQEASVMTSLRHDNLVRLIGVVLGETIFLVTEF 821
Query: 326 MENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSC 385
M G+LV++L++ +T ++ A M ++E + +HRDL A N+LV D
Sbjct: 822 MGKGNLVEYLRSRGRSVITKKDQINFATDTCAAMEYLESKRLVHRDLAARNVLVHDDGKA 1001
Query: 386 KIADFGLARLIEDNEYTAREGAKFPIKWTAPEAI 419
K++DFGLA+ + ++ + KFPIKWTAPEA+
Sbjct: 1002KVSDFGLAKFGDFSQTS----VKFPIKWTAPEAL 1091
Score = 87.0 bits (214), Expect(2) = 4e-56, Method: Compositional matrix adjust.
Identities = 39/80 (48%), Positives = 56/80 (70%)
Frame = +1
Query: 424 FTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDNCPEELYQLMRLC 483
FT KSD+WSFGILL EI + GR+PYP + +V+ ++ERGYRM P+ CP E+Y +M+
Sbjct: 1105 FTSKSDMWSFGILLWEIYSFGRVPYPRIPLTDVVMHVERGYRMEAPEGCPPEIYSIMKQA 1284
Query: 484 WKERPEDRPTFDYLRSVLED 503
W+ P +RPTF + + L +
Sbjct: 1285 WELDPNERPTFKSVLARLNN 1344
>04852
Length = 1462
Score = 162 bits (410), Expect = 3e-40, Method: Compositional matrix adjust.
Identities = 98/254 (38%), Positives = 133/254 (52%), Gaps = 31/254 (12%)
Frame = +1
Query: 275 TKVAVKSLKQ--GSMSPDAFLAEANLMKQLQ----HQRLVRLYAVVTQE-PIYIITEYME 327
+ VAVK L+ ++ F+ E +MK ++ H +V TQ P+++I E+ +
Sbjct: 22 STVAVKMLRDIVTAVEEQDFVQELQVMKAVKKMGSHINIVNFLGCCTQGGPLWVIVEFAK 201
Query: 328 NGSLVDFL-----------------------KTPSGIKLTINKLLDMAAQIAEGMAFIEE 364
NG+L DFL KTP G + LL A QIA GM F+
Sbjct: 202 NGNLRDFLESCRDGINGYGKFVSPQDPGWYTKTPGGHVIRRKNLLSYAFQIARGMEFLAS 381
Query: 365 RNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTF 424
R IHRDL A N+LV++ KIADFGL+R + Y R G + P+KW APEA+ +
Sbjct: 382 RKCIHRDLAARNVLVTEEHVLKIADFGLSR--TGDYYKKRSGGRLPVKWMAPEALFDMRY 555
Query: 425 TIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQN-LERGYRMVRPDNCPEELYQLMRLC 483
T KSDVWSFG++L EI + G +PY + N E+ L+ YRM RP+ LY +M C
Sbjct: 556 TTKSDVWSFGVVLWEIFSLGGMPYASIPNEELYSKLLDDAYRMPRPELASGNLYAIMERC 735
Query: 484 WKERPEDRPTFDYL 497
W RP DRP F L
Sbjct: 736 WLNRPSDRPEFSQL 777
>09007
Length = 1440
Score = 147 bits (372), Expect = 7e-36, Method: Compositional matrix adjust.
Identities = 80/234 (34%), Positives = 132/234 (56%), Gaps = 11/234 (4%)
Frame = -1
Query: 275 TKVAVKSLKQGSMSPDA--FLAEANLMKQLQHQRLVRLYAVVTQE--PIYIITEYMENGS 330
+VAVK L + + D FL E +M+ L H+ +VR+Y VV I ++TE S
Sbjct: 792 VQVAVKCLSKDKIHKDGQEFLKETAIMQMLDHENIVRVYGVVMDNGADIMLVTELAPMRS 613
Query: 331 LVDFLKTPSG-IKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIAD 389
L++ +K S + ++ +L D + Q+ +GM+++E + +HRDL A NIL+ KI+D
Sbjct: 612 LLECVKEVSARVDFSVPRLCDFSQQVCDGMSYLESKRLVHRDLAARNILLFSKSKVKISD 433
Query: 390 FGLA-RLIEDNEYTAREGA---KFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGR 445
G++ L EY + + + W APE+ F+ SDVW+FG+LL E THG
Sbjct: 432 VGVSGALGAGKEYYQSQQTIHLQNAVAWCAPESFRNLCFSSASDVWAFGVLLWEFFTHGF 253
Query: 446 IPYPGMTNPEVIQNLE--RGYRMVRPDNCPEELYQLMRLCWKERPEDRPTFDYL 497
P+ G+ ++++ ++ + R+ +PD CP+E Y +M CW++ P+ RPTF L
Sbjct: 252 QPWAGLNGQQIMEAVDAPQSQRLEQPDLCPKEYYAVMLKCWEQEPQRRPTFSQL 91
>07291
Length = 833
Score = 138 bits (348), Expect = 4e-33, Method: Compositional matrix adjust.
Identities = 67/164 (40%), Positives = 104/164 (63%), Gaps = 2/164 (1%)
Frame = +1
Query: 343 LTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLA-RLIEDNEY 401
LT+ +LLD QIA+GMA+++E +HR+L A N +V++ +++D+G+ L + Y
Sbjct: 40 LTVVQLLDFGRQIADGMAYLQEVKVVHRNLAARNCIVTEDGRLQLSDYGVTGSLFPQSYY 219
Query: 402 TAREG-AKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNL 460
TA + A+ +KW APE I+ F+ KSDVW+FG++L E++T G PYP + N ++ L
Sbjct: 220 TADDSPARDLVKWMAPETIDNFHFSSKSDVWAFGVVLWELLTRGITPYPDVENSSLLPYL 399
Query: 461 ERGYRMVRPDNCPEELYQLMRLCWKERPEDRPTFDYLRSVLEDF 504
+ G+RM +P PE +Y++M CW E PE RP F L L+ F
Sbjct: 400 KEGHRMKKPKQSPEPVYEMMTACWNESPEQRPDFAELNDQLKTF 531
>17300
Length = 480
Score = 124 bits (312), Expect(2) = 8e-32, Method: Composition-based stats.
Identities = 57/116 (49%), Positives = 82/116 (70%), Gaps = 4/116 (3%)
Frame = +1
Query: 355 IAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIE----DNEYTAREGAKFP 410
I+ GM + + Y+HRDL A NILV++ L CK+ADFGL+R IE + YT + G K P
Sbjct: 1 ISSGMGXLADMGYVHRDLAARNILVNEILVCKVADFGLSREIESDTTEGAYTTK-GGKIP 177
Query: 411 IKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRM 466
++WTAPEAI Y FT SDVWSFG+++ E++++G PY +N +VI+ +E+GYR+
Sbjct: 178 VRWTAPEAIAYRKFTSASDVWSFGVVMWEVMSYGERPYWNWSNQDVIKAVEKGYRL 345
Score = 30.8 bits (68), Expect(2) = 8e-32, Method: Composition-based stats.
Identities = 13/39 (33%), Positives = 19/39 (48%)
Frame = +2
Query: 471 NCPEELYQLMRLCWKERPEDRPTFDYLRSVLEDFFTATE 509
+CPE L+QLM W++ RP + L+ A E
Sbjct: 356 DCPEALHQLMLDAWQKERSHRPKMSMVVKTLDKLIRAPE 472
>20640
Length = 1492
Score = 124 bits (310), Expect = 1e-28, Method: Compositional matrix adjust.
Identities = 61/146 (41%), Positives = 84/146 (57%), Gaps = 1/146 (0%)
Frame = +1
Query: 365 RNYIHRDLRAANILVSDTLSCKIADFGLARLIED-NEYTAREGAKFPIKWTAPEAINYGT 423
R Y+HRDL N LV L KI+DFGLAR + + Y E PI+W EAI Y
Sbjct: 1 RGYVHRDLATRNCLVGHDLVVKISDFGLARSVHSVDYYRGSEHDAIPIRWMPLEAILYNK 180
Query: 424 FTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDNCPEELYQLMRLC 483
F+ +SDVWSFG++L EI PY G+T+ EV++ ++ G + P+ P +Y+LM+ C
Sbjct: 181 FSTQSDVWSFGVVLWEIFAFALQPYYGLTHEEVVRFVKEGKVLACPERTPPPMYELMKQC 360
Query: 484 WKERPEDRPTFDYLRSVLEDFFTATE 509
W RP RP+F L LE+ + E
Sbjct: 361 WHRRPATRPSFHTLHKTLENMHSKYE 438
>14116
Length = 1017
Score = 109 bits (273), Expect = 2e-24, Method: Compositional matrix adjust.
Identities = 62/185 (33%), Positives = 103/185 (55%), Gaps = 8/185 (4%)
Frame = -1
Query: 273 GHTKVAVKSLKQGS---MSPDAFLAEANLMKQLQHQRLVRLYAV---VTQEPIYIITEYM 326
G VAVK+L + + +FL EA +MK H ++ L + + P+ ++ +M
Sbjct: 552 GDILVAVKTLHNNNPREIELQSFLQEALIMKDFHHSNVLTLIGICLNLDDMPL-VVLPFM 376
Query: 327 ENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCK 386
++G L+ +++ + TI L+ IA GM ++ ++HRDL A N ++ + K
Sbjct: 375 KHGDLLTYIRDDQH-QPTIKDLIMYGVDIARGMDYLAGLKFVHRDLAARNCMLDEDFHVK 199
Query: 387 IADFGLARLIEDNEYTAREG--AKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHG 444
+ADFGLAR I + EY + E AK P+KW A E++ G + K+DVWS+G++L E++T G
Sbjct: 198 VADFGLARDIYEKEYYSSENKKAKLPVKWMALESLEKGNYDSKTDVWSYGVVLWELLTRG 19
Query: 445 RIPYP 449
P
Sbjct: 18 SDALP 4
>18996
Length = 491
Score = 107 bits (268), Expect = 9e-24, Method: Compositional matrix adjust.
Identities = 65/158 (41%), Positives = 87/158 (55%), Gaps = 10/158 (6%)
Frame = +2
Query: 368 IHRDLRAANILVSDTLSCKIADFGLARLIE-DNEYTAREGAKFPIKWTAPEAINYGTFTI 426
IHRDL A NILV D KI+DFGLA+ D Y PIKW +PEAI F+
Sbjct: 2 IHRDLAARNILV-DRSCVKISDFGLAQFANADGYYYGISQRDIPIKWYSPEAIETCKFSS 178
Query: 427 KSDVWSFGILLTEIVTHGRIP--YPG--MTNPEVIQNLERGYRMVRPDNCPEELY-QLMR 481
SDVWS+G+ L E+ + G IP PG +T E + L +G R+ +P+ C + +Y +LMR
Sbjct: 179 YSDVWSYGVTLFEMFSRGEIPNLLPGHDLTQEEFLNRLRKGERLPKPELCSDFVYSELMR 358
Query: 482 LCWKERPEDRPTFDYLRSVLE----DFFTATEGQYQPQ 515
CW E P+ RPTF + ++ D + G Q Q
Sbjct: 359 PCWHEMPKSRPTFHQIIQIIAREMGDNISGXAGSTQQQ 472
>17637
Length = 447
Score = 105 bits (262), Expect = 4e-23, Method: Compositional matrix adjust.
Identities = 50/132 (37%), Positives = 77/132 (58%), Gaps = 1/132 (0%)
Frame = +1
Query: 376 NILVSDTLSCKIADFGLARLIEDNEYTAR-EGAKFPIKWTAPEAINYGTFTIKSDVWSFG 434
N ++ D L K+ D L+R + +Y +G PIKW + EA+ + SDVWSFG
Sbjct: 1 NCVIDDQLRVKLTDSALSRDLFSGDYNCLGDGEYRPIKWLSLEALQKSHYNEGSDVWSFG 180
Query: 435 ILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDNCPEELYQLMRLCWKERPEDRPTF 494
+L+ E+ T G++PY + E+ L+ GYR+ +P NCP+EL+ +M CW P +RP+F
Sbjct: 181 VLMWEMCTLGKLPYAEIDPYEMEHYLKDGYRLAQPFNCPDELFTIMAYCWASMPAERPSF 360
Query: 495 DYLRSVLEDFFT 506
L+ L +F T
Sbjct: 361 SQLQICLSEFHT 396
>22005
Length = 873
Score = 84.0 bits (206), Expect(2) = 5e-23, Method: Compositional matrix adjust.
Identities = 74/247 (29%), Positives = 113/247 (45%), Gaps = 47/247 (19%)
Frame = +1
Query: 242 RNLDNGGFYISPRITFPGLHELVRHYTRYYNGHTKVAVKSLKQGSMSPDA---FLAEANL 298
R++ G F ++ F GL LV + K LK+ + S D F EA+L
Sbjct: 1 RDIGQGAFGRVSKLKFLGLASLVGELIP--EKRP*LL*KMLKEDA-SEDLQSDFEREASL 171
Query: 299 MKQLQHQRLVRLYAVVT-QEPIYIITEYMENGSLVDFLK--TPSGIKLTI----NKLLDM 351
M H +V+L V +P+ ++ E+M G L DFL+ +P L + N ++D+
Sbjct: 172 MADFDHPNIVKLLGVCAIGKPMCLLFEFMSKGDLNDFLRLCSPENYNLPVSRSQNLVVDL 351
Query: 352 ------------------------------------AAQIAEGMAFIEERNYIHRDLRAA 375
+ QI+ GMA++ +++Y+HRDL A
Sbjct: 352 EDGLRVEVEAEECEKDTQSEDRDCSGMLXTKDQLYISQQISAGMAYLAQKDYVHRDL-AT 528
Query: 376 NILVSDTLSCKIADFGLARLIED-NEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFG 434
+ S T I+DFGLAR + + Y E PI+W EAI Y F+ +SDVWSFG
Sbjct: 529 RTVXSRTT*S*ISDFGLARSVHSVDYYRGSEQDAIPIRWMPLEAILYSKFSTQSDVWSFG 708
Query: 435 ILLTEIV 441
++L EI+
Sbjct: 709 VVLWEIL 729
Score = 42.0 bits (97), Expect(2) = 5e-23, Method: Compositional matrix adjust.
Identities = 16/42 (38%), Positives = 28/42 (66%)
Frame = +3
Query: 447 PYPGMTNPEVIQNLERGYRMVRPDNCPEELYQLMRLCWKERP 488
PY G+T+ EV+ ++ G + +P P ++Y+LM+ CW+ RP
Sbjct: 744 PYYGLTHEEVVNYVKAGKILEQPTKTPHQVYELMKQCWQRRP 869
>08294
Length = 1849
Score = 103 bits (258), Expect = 1e-22, Method: Compositional matrix adjust.
Identities = 58/198 (29%), Positives = 100/198 (50%), Gaps = 13/198 (6%)
Frame = +2
Query: 317 EPIYIITEYMENGSLVDFL-------------KTPSGIKLTINKLLDMAAQIAEGMAFIE 363
EP ++ITEY + G L FL + P+ L +++ L M Q+A GM +
Sbjct: 926 EPHFLITEYCDWGDLKQFLLATRNDNGRGRGTRVPA---LALSQKLGMGQQVAAGMEALS 1096
Query: 364 ERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGT 423
+ +H DL A N+L++ + K+A L+ + +EY P++W PE + +
Sbjct: 1097 NQGLVHGDLAARNVLLTSRMQLKVARPALSGDVYASEYYPLHQRLVPLRWLPPEGVLEDS 1276
Query: 424 FTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDNCPEELYQLMRLC 483
T DVW+FG+ L E++ +PY M++ EV+++L+ + + P L L++ C
Sbjct: 1277 ATTCGDVWAFGVFLWEVLQLADLPYRLMSDEEVLRSLQHSQAALDSPDAPPALLSLLQRC 1456
Query: 484 WKERPEDRPTFDYLRSVL 501
++P RP F + SVL
Sbjct: 1457 TAQQPSQRPPFSEICSVL 1510
>07940
Length = 1336
Score = 99.8 bits (247), Expect = 2e-21, Method: Compositional matrix adjust.
Identities = 50/110 (45%), Positives = 69/110 (62%), Gaps = 1/110 (0%)
Frame = -3
Query: 343 LTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYT 402
LT L+ A Q+A GM ++ + IHRDL A N+LV++ KIADFGL R ++ +Y
Sbjct: 356 LTPKDLISYAYQVARGMEYLASKQCIHRDLAARNVLVAEEYVLKIADFGLTRNLQQFDYY 177
Query: 403 ARE-GAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGM 451
+ + P+KW APEA+ +T KSDVWS+G+LL EI T G PYP +
Sbjct: 176 RKTTDGRLPVKWMAPEALFDRKYTSKSDVWSYGVLLWEIFTLGGNPYPSV 27
Score = 38.5 bits (88), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 23/70 (32%), Positives = 39/70 (55%), Gaps = 4/70 (5%)
Frame = -3
Query: 272 NGHTKVAVKSLKQGSMSPDA--FLAEANLMKQL-QHQRLVRLYAVVTQE-PIYIITEYME 327
N VAVK LK+ + + + E +MK + +H+ ++ L TQ +Y+I E+
Sbjct: 758 NNSVTVAVKMLKEDATDREMMDLIREMEMMKVIGKHKNIINLLGCCTQRGALYVIVEFAP 579
Query: 328 NGSLVDFLKT 337
+G+L DFLK+
Sbjct: 578 HGNLRDFLKS 549
>14477
Length = 493
Score = 86.3 bits (212), Expect = 3e-17, Method: Composition-based stats.
Identities = 46/135 (34%), Positives = 77/135 (57%), Gaps = 5/135 (3%)
Frame = -1
Query: 277 VAVKSLKQGSMSPDA---FLAEANLMKQLQHQRLVRLYAVVTQEPIYIITEYMENGSLVD 333
VA+K LK + P + EA +MK++ H +VRL + E + ++ E + G L
Sbjct: 400 VAIKVLKNADLDPSVQSELIKEAEVMKKMDHMHIVRLIGLCEGETMMLVLELAKLGPLNK 221
Query: 334 FLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLA 393
FL P L + +L++ Q+++GM ++E ++HRDL A NIL+ D KI+DFG++
Sbjct: 220 FL--PKNKHLPLWNILELMWQVSQGMEYLEANKFVHRDLAARNILLCDEHFAKISDFGMS 47
Query: 394 RLI--EDNEYTAREG 406
+ + E+N Y A+E
Sbjct: 46 KTLSRENNYYMAQEA 2
>13305
Length = 549
Score = 84.7 bits (208), Expect = 8e-17, Method: Compositional matrix adjust.
Identities = 37/89 (41%), Positives = 52/89 (58%)
Frame = +2
Query: 406 GAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYR 465
+ PI+W A E++ T+T +SDVWSFG++L EI T G PY ++ L+ GYR
Sbjct: 2 STRVPIRWMAVESLFNNTYTTQSDVWSFGVVLWEIFTLGGTPYSSTDTQQLFAFLKDGYR 181
Query: 466 MVRPDNCPEELYQLMRLCWKERPEDRPTF 494
+ RP C + Y +M CW E + RPTF
Sbjct: 182 LKRPKLCDQNTYAMMLQCWNENAQRRPTF 268
>01718
Length = 959
Score = 82.8 bits (203), Expect = 3e-16, Method: Compositional matrix adjust.
Identities = 69/242 (28%), Positives = 115/242 (47%), Gaps = 15/242 (6%)
Frame = +3
Query: 279 VKSLKQGSMSPDA--FLAEANLMKQLQHQRLVRLYAVVTQE-PIYIITEYMENGSLVDFL 335
V +LK +M+ + L E L+ +LQH ++R V E ++ +TEY+ +G+L L
Sbjct: 228 VMALKMNTMTSNRHNMLREVQLLNRLQHANILRFMGVCVHEGQLHALTEYIPSGNLEQLL 407
Query: 336 KTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILV----SDTLSCKIADFG 391
+ +L + + + +A G+ ++ +IHRDL + NIL+ + IADFG
Sbjct: 408 EKKDE-ELPWTQRIQLTLGLARGLDYLHSTRFIHRDLTSKNILIRREDNHGYHAVIADFG 584
Query: 392 LARLIE---DNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPY 448
LA I D E G+ + W APE +N + ++D++S GI++ EI RIP
Sbjct: 585 LATKIPDPLDKEKLPTVGSPY---WMAPEVLNGHFYNERADLFSVGIIMCEIT--ARIP- 746
Query: 449 PGMTNPEVIQNLER-GYRMVRPDN----CPEELYQLMRLCWKERPEDRPTFDYLRSVLED 503
+P+++ + G V CP + QL C + P+ RP + LE
Sbjct: 747 ---ADPDIMPRMNNFGVDYVALSEMISYCPLDYLQLAFKCCQVDPQKRPRGVEIIEWLEK 917
Query: 504 FF 505
F
Sbjct: 918 IF 923
>07833
Length = 1504
Score = 77.0 bits (188), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 60/223 (26%), Positives = 109/223 (48%), Gaps = 12/223 (5%)
Frame = -3
Query: 292 FLAEANLMKQLQHQRLVRLYAVVTQEP-IYIITEYMENGSLVDFLKTPSGIKLTINKLLD 350
F+ E ++ H ++ + A Q P + +I+++M GSL + L SGI + N+ L
Sbjct: 1478 FMEEFPRLRIFNHPNVLPVLACCNQPPNLVLISQFMPFGSLYNTLHGESGIVVDQNQSLR 1299
Query: 351 MAAQIAEGMAFIEER-----NYIHRDLRAANILVSDTLSCKI--ADFGLARLIEDNEYTA 403
A IA GM F+ N++ L + ++++ + L+ +I AD+ +
Sbjct: 1298 FAMDIARGMEFLHSMEPTIPNFL---LTSKHVMIDEDLTARINMADYCFS--------FH 1152
Query: 404 REGAKFPIKWTAPEAINY---GTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEV-IQN 459
+G + W APEA+ T +D+WSF IL+ E+ T +P+ +++ EV ++
Sbjct: 1151 EKGKVYSPAWMAPEALQRRPDDINTRAADMWSFAILMWELETR-EVPFAELSSMEVGMKV 975
Query: 460 LERGYRMVRPDNCPEELYQLMRLCWKERPEDRPTFDYLRSVLE 502
G R+ P + +L+++C E P RP FD + +LE
Sbjct: 974 ALEGLRISIPPGISLHMSRLIKICMNEEPGKRPRFDMIIPILE 846
>29581
Length = 1278
Score = 75.5 bits (184), Expect = 5e-14, Method: Compositional matrix adjust.
Identities = 53/187 (28%), Positives = 98/187 (52%), Gaps = 10/187 (5%)
Frame = -2
Query: 282 LKQGSMSPDAFLAEANLMKQLQHQRLVRLYAVV---TQEPIYIITEYMEN--GSLVDFLK 336
L++ +SP + + L+HQ +V+L VV + + ++++ EY E SL+D +
Sbjct: 1244 LERDMVSPSVVCVRSTFLLNLRHQNIVQLQEVVVGKSLDSLFLVMEYCEQDLASLLDNMP 1065
Query: 337 TPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLI 396
P + +++ + Q+ +G+ ++ E IHRDL+ +N+L++D KIADFGLAR
Sbjct: 1064 AP----FSESQVKCIVLQLLKGLRYLHEAFIIHRDLKVSNLLMTDKGCVKIADFGLAR-- 903
Query: 397 EDNEYTAREGAKFP----IKWTAPEAI-NYGTFTIKSDVWSFGILLTEIVTHGRIPYPGM 451
Y + P + + APE + T + D+WS G +L E++ H + PG
Sbjct: 902 ---NYGKPQKPMTPKVVTLWYRAPELLFGSKTHSTAIDMWSAGCILGELLGHKPL-MPGR 735
Query: 452 TNPEVIQ 458
++ + I+
Sbjct: 734 SDLQQIE 714
>17253
Length = 483
Score = 72.8 bits (177), Expect = 3e-13, Method: Composition-based stats.
Identities = 45/153 (29%), Positives = 75/153 (49%), Gaps = 16/153 (10%)
Frame = -1
Query: 277 VAVKSLKQGSMSPDA--FLAEANLMKQL-QHQRLVRLYAVVT-QEPIYIITEYMENGSLV 332
VAVK+ + + + FL E ++M++L +H +V T +P I+ E+ +G L+
Sbjct: 459 VAVKTHNEAATDAEKSEFLRELSIMRKLPRHPNVVSFMGCCTMSDPALILMEFCCHGDLL 280
Query: 333 DFLK----------TPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDT 382
FL+ T + LT A +A GMA + +HRD+ A N+L+S+
Sbjct: 279 SFLRKRRPDRTVFLTSTANDLTARDFFSFALHVARGMAHVANNKIVHRDVAARNVLISER 100
Query: 383 LSCKIADFGLARLIEDNE--YTAREGAKFPIKW 413
CK++DFGL+R + D Y P++W
Sbjct: 99 NVCKVSDFGLSRRVGDQNDVYEIVSRRPLPLRW 1
>01060
Length = 1800
Score = 71.2 bits (173), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 54/209 (25%), Positives = 102/209 (48%), Gaps = 5/209 (2%)
Frame = +1
Query: 264 VRHYTRYYNGHTKVAVKSLK-QGSMS--PDAFLAEANLMKQLQHQRLVRLYAVVTQ-EPI 319
V + R+ K+A+K ++ +GS P + + E ++++L+H +V L V+ + E +
Sbjct: 118 VVYKCRHRATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTNIVCLEDVIMEDERL 297
Query: 320 YIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILV 379
+++ E++ + K P G+ L + QI G+ F +R +HRDL+ N+L+
Sbjct: 298 FLVFEFLSMDLKMYIDKFPEGVVLDRRLVKSYVFQIVTGIXFCHQRRIVHRDLKPQNLLI 477
Query: 380 SDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAI-NYGTFTIKSDVWSFGILLT 438
+ T + KIADFG+AR A + + APE + ++ DVWS G +
Sbjct: 478 NHTGAIKIADFGMARTFA-LPVRAYTHEVVTLWYRAPEILMGASKYSTPVDVWSIGTIFA 654
Query: 439 EIVTHGRIPYPGMTNPEVIQNLERGYRMV 467
+++ I P I L + +R++
Sbjct: 655 DML----IRTPIFKGDSEIDQLFKIFRII 729
>12721
Length = 821
Score = 70.5 bits (171), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 39/168 (23%), Positives = 84/168 (50%), Gaps = 2/168 (1%)
Frame = +1
Query: 276 KVAVKSLK-QGSMSPDAFLAEANLMKQLQHQRLVRLY-AVVTQEPIYIITEYMENGSLVD 333
++AVK + + + E +M+ H +V +Y + + + ++++ E+ME G+L D
Sbjct: 166 QMAVKKMDLRKQQRRELLFNEVVVMRDYHHPNIVEMYNSYLVNDELWVVMEFMEGGALTD 345
Query: 334 FLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLA 393
+ + ++ ++ + + +AF+ IHRD+++ +IL+S K+ DFG
Sbjct: 346 IV---TNNRMDEVQIATVCRACLKALAFLHANGVIHRDIKSDSILLSHDGKVKLXDFGFC 516
Query: 394 RLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIV 441
+ + + P W APE I+ + + D+WS GI++ E++
Sbjct: 517 AQVTQDLQKRKSLVGTPY-WMAPEVISRLPYGPEVDIWSLGIMVMEMI 657
>13592
Length = 980
Score = 70.5 bits (171), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 50/208 (24%), Positives = 102/208 (49%), Gaps = 11/208 (5%)
Frame = +2
Query: 295 EANLMKQLQHQRLVRLYAV-VTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAA 353
E +++ ++H+ LVR Y + V +E + I E G+L ++ G+ +++ A
Sbjct: 131 ELKILEGIKHKNLVRYYGIEVHREELLIFMELCSEGTLESLVELTGGLPEALSR--RFTA 304
Query: 354 QIAEGMAFIEERNYIHRDLRAANI-LVSDTLSCKIADFGLARLIEDNE--------YTAR 404
Q+ G+A + + +HRD++ ANI LV + S K+ DFG A I+ + Y
Sbjct: 305 QLLSGVAELHKHGIVHRDIKTANIFLVDGSNSLKLGDFGSAVKIQAHTTVPGELQGYVGT 484
Query: 405 EGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGM-TNPEVIQNLERG 463
+ P +T + +G +D+WS G ++ E+ + G+ P+ +N +++ + G
Sbjct: 485 QAYMAPEVFTKTNSDGHGRL---ADIWSVGCVVVEMAS-GKRPWAQFDSNFQIMFKVGMG 652
Query: 464 YRMVRPDNCPEELYQLMRLCWKERPEDR 491
+ P++ +E + + C + P+ R
Sbjct: 653 EKPQAPESLSQEGHDFIDHCLQHDPKQR 736
>18921
Length = 697
Score = 69.3 bits (168), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 45/165 (27%), Positives = 82/165 (49%), Gaps = 3/165 (1%)
Frame = +2
Query: 279 VKSLKQGSMSPD--AFLAEANLMKQLQHQRLVRLY-AVVTQEPIYIITEYMENGSLVDFL 335
V ++KQ + D + E ++M+Q + +V+ Y + ++I+ EY GS+ D +
Sbjct: 110 VLAIKQVPVDTDLQEIIKEISIMQQCDSKYIVKYYGSYFKNTDLWIVMEYCGAGSVSDIM 289
Query: 336 KTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARL 395
+ + L ++ + +G+ ++ R IHRD++A NIL+++ K+ADFG+A
Sbjct: 290 RLRNK-TLVEREIATILYYTLKGLXYLHSRRKIHRDIKAGNILLNNEGHAKLADFGVAGQ 466
Query: 396 IEDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEI 440
+ D P W APE I + +D+WS GI E+
Sbjct: 467 LTDTMAKRNTVIGTPY-WMAPEVIQEIGYDCVADIWSLGITALEM 598
>01707
Length = 757
Score = 68.9 bits (167), Expect = 4e-12, Method: Compositional matrix adjust.
Identities = 51/184 (27%), Positives = 96/184 (52%), Gaps = 7/184 (3%)
Frame = +1
Query: 277 VAVKSLKQGSMSP---DAFLAEANLMKQLQHQRLVRLYAVVTQEP-IYIITEYMENGSLV 332
VA+K + P + E ++KQL+H LVRL V ++ ++++ +Y+++ L
Sbjct: 148 VAIKKFVESEDDPLIKKIAMREIRMLKQLKHPNLVRLIEVFRRKKRLHLVFDYVDHTLLN 327
Query: 333 DFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGL 392
+ + P G+ + K + +A + F + N IHRD++ NIL++ K+ DFG
Sbjct: 328 ELDRYPRGLPEPMVKRIIYQTLLA--VNFCHQYNTIHRDVKPENILITRQGQVKLCDFGF 501
Query: 393 ARLIE--DNEYTAREGAKFPIKWTAPEAINYGT-FTIKSDVWSFGILLTEIVTHGRIPYP 449
AR++ +EYT ++ + APE + T + DVW+ G + E++T G+ +P
Sbjct: 502 ARILTGPGDEYTDYVATRW---YRAPELLVGDTQYGPPVDVWAIGCVFAELLT-GQALWP 669
Query: 450 GMTN 453
G ++
Sbjct: 670 GRSD 681
>14126
Length = 1265
Score = 68.2 bits (165), Expect = 7e-12, Method: Compositional matrix adjust.
Identities = 50/179 (27%), Positives = 88/179 (49%), Gaps = 12/179 (6%)
Frame = +3
Query: 277 VAVKSLKQGSMS---PDAFLAEANLMKQLQ---HQRLVRLYAV----VTQEPIYI--ITE 324
VA+K ++ + P + E +++KQL+ H +VRL V +T I + + E
Sbjct: 276 VAMKRIRLNNTEEGMPMMAIREISMLKQLEQYEHPNVVRLLDVSHNTITDREIRLNLVFE 455
Query: 325 YMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLS 384
Y+E+ K PS L +++ D+ Q+ G+ F+ +HRDL+ N+L+S
Sbjct: 456 YIEHDLATYLAKCPSP-GLGPDRIKDLMLQLLNGVDFLHSNRIVHRDLKPQNLLISKDGR 632
Query: 385 CKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTH 443
K+ADFGLAR+ + + A + + +PE + + D+WS G + E+ T
Sbjct: 633 LKLADFGLARIY--SFHMALTTVVVTLWYRSPEVLMQAEYGTSVDIWSCGCIFAELFTR 803
>00715
Length = 1788
Score = 66.6 bits (161), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 49/172 (28%), Positives = 82/172 (47%), Gaps = 27/172 (15%)
Frame = +1
Query: 349 LDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLI------------ 396
L +A Q+A G+ ++ N +H DL+ AN L++ L +IADFG +
Sbjct: 247 LSLALQMARGLHYLHSINIVHLDLKPANCLLTRDLKLRIADFGCCHQLTPTGLDMGEREG 426
Query: 397 ----EDNEYTAREGA-----KFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIP 447
+ E T +GA + + APE + +++SDV+S GI L ++ T + P
Sbjct: 427 GMAGNELELTPVQGAWKNELAGTLAYRAPELLKGLQPSVRSDVYSLGITLWQMCTR-QGP 603
Query: 448 YPGMTNPEVI-QNLERGYRMVRPDNCPEELYQLM-----RLCWKERPEDRPT 493
Y G+ V+ Q + + R P + ++ +++M CW R EDRPT
Sbjct: 604 YEGVPAHAVVYQVVSKDLRPCPPPSTEDDPFEVMFRDLYTQCWARRVEDRPT 759
>01966
Length = 1735
Score = 65.5 bits (158), Expect = 5e-11, Method: Compositional matrix adjust.
Identities = 39/130 (30%), Positives = 73/130 (56%), Gaps = 4/130 (3%)
Frame = -1
Query: 269 RYYNGHTKVAVKSLK-QGSMS--PDAFLAEANLMKQLQHQRLVRLYAVVTQ-EPIYIITE 324
R+ K+A+K ++ +GS P + + E ++++L+H +V L V+ + E ++++ E
Sbjct: 1651 RHRATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTNIVCLEDVIMEDERLFLVFE 1472
Query: 325 YMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLS 384
++ + K P G+ L + QI G+ F +R +HRDL+ N+L++ T +
Sbjct: 1471 FLSMDLKMYIDKFPEGVVLDRRLVKSYVFQIVTGINFCHQRRIVHRDLKPQNLLINHTGA 1292
Query: 385 CKIADFGLAR 394
KIADFG+AR
Sbjct: 1291 IKIADFGMAR 1262
>14420
Length = 528
Score = 65.1 bits (157), Expect = 7e-11, Method: Compositional matrix adjust.
Identities = 39/162 (24%), Positives = 80/162 (49%), Gaps = 3/162 (1%)
Frame = +2
Query: 290 DAFLAEANLMKQLQHQRLVR-LYAVVTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKL 348
+ + E +M++ Q+ +V L + + E ++++ E++ GSL D + + ++
Sbjct: 35 ELIINEILVMRENQNPNIVNYLDSYLVGEELWVVMEFLAGGSLTDVVTETC---MDEGQI 205
Query: 349 LDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLI--EDNEYTAREG 406
+ + + + F+ E IHRD+++ NIL+ S K+ DFG + E ++ + G
Sbjct: 206 AAVCRECLQALEFLHENQVIHRDIKSDNILLGMDGSVKLTDFGFCAQLSPEQSKRSTMVG 385
Query: 407 AKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPY 448
+ W APE + + D+WS G++ E++ G PY
Sbjct: 386 TPY---WMAPEVVTRKQYGPTVDIWSLGVMCIEMI-EGEPPY 499
>19301
Length = 712
Score = 65.1 bits (157), Expect = 7e-11, Method: Compositional matrix adjust.
Identities = 40/119 (33%), Positives = 63/119 (52%), Gaps = 1/119 (0%)
Frame = +2
Query: 276 KVAVKSLKQGSMSPDAFLAEANLMKQLQHQRLVRLYAVVTQEPIY-IITEYMENGSLVDF 334
+VAVK ++ D + +++L H ++ V TQ P Y II EY G L +
Sbjct: 380 EVAVKKVR------DIKETDIRNLRKLNHPNIISFKGVCTQAPCYCIIMEYCPYGQLYEV 541
Query: 335 LKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLA 393
L+ G ++ +LD + QIA GM ++ IHRDL++ N+LV+ KI+DFG +
Sbjct: 542 LR--DGKEIPPALVLDWSKQIASGMNYLHSHKIIHRDLKSPNVLVAKNDVVKISDFGTS 712
>27546
Length = 426
Score = 63.9 bits (154), Expect = 1e-10, Method: Composition-based stats.
Identities = 33/108 (30%), Positives = 59/108 (54%), Gaps = 1/108 (0%)
Frame = -1
Query: 292 FLAEANLMKQLQHQRLVRLYAVVTQEP-IYIITEYMENGSLVDFLKTPSGIKLTINKLLD 350
F E ++ +L H ++++++++ + P I+I Y E G ++ +K I K+
Sbjct: 339 FPRELEILTRLDHPNIIQIHSILQRGPKIFIFMRYAEKGDMLSHIKKTGPIDEAQTKVWF 160
Query: 351 MAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIED 398
Q+A+ + ++ + HRDL+ NIL+S L+ KIADFG AR D
Sbjct: 159 F--QMAKALQYLHSHDIAHRDLKCENILLSKRLNVKIADFGFARYCRD 22
>18484
Length = 635
Score = 63.2 bits (152), Expect = 3e-10, Method: Compositional matrix adjust.
Identities = 34/109 (31%), Positives = 61/109 (55%)
Frame = +1
Query: 352 AAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPI 411
AA+IA G+ F+ ++ I+RDL+ N+++ KIADFG+ + + T R P
Sbjct: 61 AAEIAVGLFFLHDQGIIYRDLKLDNVMLDSEGHIKIADFGMCKEGMTGDATTRTFCGTP- 237
Query: 412 KWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNL 460
+ APE + Y ++ D W++G+LL E++ G+ P+ G E+ ++
Sbjct: 238 DYIAPEIVLYQPYSKSVDWWAYGVLLFEMLA-GQPPFDGEDEDELFSSI 381
>12672
Length = 773
Score = 62.8 bits (151), Expect = 3e-10, Method: Compositional matrix adjust.
Identities = 43/166 (25%), Positives = 72/166 (43%), Gaps = 17/166 (10%)
Frame = +3
Query: 356 AEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPI---K 412
A G+ ++ + ++HRD++ ANIL+ + K+ DF E + A I
Sbjct: 21 ASGIQYLNDNGHVHRDIKTANILLDSEYTAKVGDFATVVSAPSGEGKTVQNASVVIGTAA 200
Query: 413 WTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIP--------------YPGMTNPEVIQ 458
+ APEAI++ T K D +SFG++L E++T G + + PE I
Sbjct: 201 YLAPEAIHFDVST-KLDSYSFGVVLLEVIT-GLVAQDYSREERTLSSHIMENVEEPEEIH 374
Query: 459 NLERGYRMVRPDNCPEELYQLMRLCWKERPEDRPTFDYLRSVLEDF 504
+ PD ++LY + C + RP +R LE+
Sbjct: 375 DFVDQSAGTWPDGAVDKLYDISMRCLNLSKKQRPNVKDIRPELEEL 512
>01756
Length = 1858
Score = 62.0 bits (149), Expect = 6e-10, Method: Compositional matrix adjust.
Identities = 51/195 (26%), Positives = 89/195 (45%), Gaps = 16/195 (8%)
Frame = -3
Query: 268 TRYYNGHTKVAVKSLKQGSMSPDAFLAEANLMKQLQHQRLVRLYAVVTQEP--------- 318
T+ KV + + K+G P L E +++ L H+ +V L + + +
Sbjct: 1670 TKQVVAMKKVLMDNEKEGF--PITALREIKILQLLNHENVVDLIEICSTKATSANRYKSM 1497
Query: 319 IYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANIL 378
Y++ E+ E+ L L S + + ++ ++ Q+ G+ +I +HRD++AANIL
Sbjct: 1496 FYLVFEFCEH-DLAGLLSNMSVV-FNLPEIKEVMKQLMNGLYYIHRNKILHRDMKAANIL 1323
Query: 379 VSDTLSCKIADFGLAR-----LIEDNEYTAREGAKFPIKWTAPEAINYG--TFTIKSDVW 431
++ K+ADFGLAR L + N YT R W P + G ++ D W
Sbjct: 1322 ITKQGVLKLADFGLARAFSVNLRQPNRYTNR----VVTLWYRPPELLLGDRNYSTAIDQW 1155
Query: 432 SFGILLTEIVTHGRI 446
G ++ E+ T I
Sbjct: 1154 GAGCIMAEMWTRNPI 1110
>04591
Length = 1117
Score = 60.8 bits (146), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 42/166 (25%), Positives = 82/166 (49%), Gaps = 14/166 (8%)
Frame = -2
Query: 289 PDAFLAEANLMKQLQHQRLVRLYAVVTQEP---------IYIITEYMEN--GSLVDFLKT 337
P L E +++QL+H+ +V+L + + Y+I EY + L++ L+
Sbjct: 1089 PITALREIKILQQLEHENVVQLQEICHTQAGPYNRYKSTFYLIFEYCDYDLAGLLNNLR- 913
Query: 338 PSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLAR-LI 396
+K ++ ++ +Q+ G+ +I + +HRD++AANIL++ K+ADFGL+R +
Sbjct: 912 ---VKFSLADKKNLMSQLLNGLFYIHTKQILHRDIKAANILLTRDGVLKLADFGLSRPWV 742
Query: 397 EDNEYTAREGAKFPIKWTAPEAINYG--TFTIKSDVWSFGILLTEI 440
+ T R W P + G + + D+W G ++ E+
Sbjct: 741 KSKRLTNR----VVTLWYRPPELLLGEREYGPEIDMWGVGCIMAEM 616
>00300
Length = 2318
Score = 60.8 bits (146), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 50/219 (22%), Positives = 99/219 (45%), Gaps = 7/219 (3%)
Frame = -1
Query: 295 EANLMKQLQHQRLVRLYAV-VTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAA 353
E + + +QH+ LV+ Y V V ++ + + EY + G++ + K + L +
Sbjct: 1511 EIKIFEGIQHENLVKYYGVEVHKDEMLMFMEYCDTGTIEEAAK----MGLPEYLIRRYTR 1344
Query: 354 QIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKF--PI 411
+I + + E + +HRD++ ANI ++ K+ DFG + ++ + E
Sbjct: 1343 EIVLAVNHLHENSIVHRDIKGANIFLTSNGHVKLGDFGCSVKLKSHTTMPGEFHNLVGTT 1164
Query: 412 KWTAPEAI---NYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNP-EVIQNLERGYRMV 467
+ APE + G + +D+WS G ++ E+ T G+ P+ + N +++ + G++
Sbjct: 1163 AYMAPEVFTQNDQGGYGRAADIWSLGCVVIEMAT-GKRPWHDLDNNYQIMYKVGIGHKPA 987
Query: 468 RPDNCPEELYQLMRLCWKERPEDRPTFDYLRSVLEDFFT 506
PD+ E + L P R L L+ FT
Sbjct: 986 VPDSLSVEGKHFLDLIMCHDPAQRALASQL---LDHTFT 879
>25550
Length = 941
Score = 60.8 bits (146), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 28/63 (44%), Positives = 39/63 (61%)
Frame = +3
Query: 446 IPYPGMTNPEVIQNLERGYRMVRPDNCPEELYQLMRLCWKERPEDRPTFDYLRSVLEDFF 505
+ YPG+ EV LERGYRM RP P ++Y LM CW+ P++RPTF + +LE+ F
Sbjct: 36 VXYPGVDLTEVYHLLERGYRMERPQGTPADVYILMLKCWQWDPKERPTFKEIHYLLENMF 215
Query: 506 TAT 508
+
Sbjct: 216 EKS 224
>07836
Length = 1478
Score = 58.9 bits (141), Expect = 5e-09, Method: Compositional matrix adjust.
Identities = 61/220 (27%), Positives = 105/220 (47%), Gaps = 45/220 (20%)
Frame = -1
Query: 319 IYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNY--------IHR 370
+++IT+Y ENGSL D+L + L +++L +A G+A + + HR
Sbjct: 1328 LFLITDYHENGSLHDYLLSRV---LDSSEMLALAHSAICGLAHLHIEIFGTRGKPAIAHR 1158
Query: 371 DLRAANILVSDTLSCKIADFGLA-RLI-EDNEYTA----REGAKFPIKWTAPEAI----- 419
D+++ NILV +C IAD GLA R I E NE R+G K ++ APE +
Sbjct: 1157 DIKSKNILVKKNGTCCIADLGLAVRYISESNEVDVAPNPRQGTK---RYMAPEVLEMLLN 987
Query: 420 --NYGTFTIKSDVWSFGILLTEI----VTHG-----RIPY-------PGMTNPEVIQNLE 461
N+ F ++D+++FG+++ EI V G ++P+ P + ++ +++
Sbjct: 986 VKNFDAFK-QADMYAFGLVMWEIARCCVIGGVAEEYQVPFYNCLPHDPSFEDVRLVVSVD 810
Query: 462 RGYRMVRPDN--------CPEELYQLMRLCWKERPEDRPT 493
+ VRPD + + ++M CW P R T
Sbjct: 809 K----VRPDIPLRWQEDPIMKVMVKVMCECWSGNPAARLT 702
>17975
Length = 449
Score = 56.6 bits (135), Expect = 2e-08, Method: Composition-based stats.
Identities = 41/139 (29%), Positives = 69/139 (49%), Gaps = 6/139 (4%)
Frame = +3
Query: 261 HELVRHYTRYYNGHTKVAVKSL---KQGSMSPDAFLAEANLMKQLQHQRLVRLYAVV-TQ 316
H V R+ KVAVK + K +S E MK +QH +VRLY V+ TQ
Sbjct: 3 HFAVVKLARHVFTGEKVAVKVIDKTKLDEVSRSHLFQEVRCMKLVQHPNVVRLYEVIDTQ 182
Query: 317 EPIYIITEYMENGSLVDF-LKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAA 375
+Y+I E + G + D+ ++ G++ + K QI E +++ + + +HRDL+
Sbjct: 183 TKLYLILELGDGGDMYDYIMRHSGGLEEKLAK--RYFRQIVEAISYCHKLHVVHRDLKPE 356
Query: 376 NILVSDTLS-CKIADFGLA 393
N++ + K+ DFG +
Sbjct: 357 NVVFFEKPGLVKLTDFGFS 413
>13066
Length = 551
Score = 56.6 bits (135), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 45/184 (24%), Positives = 85/184 (46%), Gaps = 10/184 (5%)
Frame = +3
Query: 261 HELVRH--YTRYYNGHTKVAVKSLKQGSMSPDA----FLAEANLMKQLQHQRLVRLYAVV 314
H +V H + Y + K+A K + + D F E +L+ +L H ++++++++
Sbjct: 6 HAVVVHGTFNDGYGRNIKLACKIIDKEKAPVDFVEKFFPRELDLLTKLDHPYIIQIHSIL 185
Query: 315 TQEPI-YIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLR 373
+ P +I + E G L+ +++ +K K+ Q+ + ++ + HRDL+
Sbjct: 186 QRXPKNFIFMRFAERGDLLTYIQEVGFVKEKQAKI--WFYQMTTALNYLHSYDVAHRDLK 359
Query: 374 AANILVSDTLSCKIADFGL--ARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIK-SDV 430
NIL+S + K+ADFG A + E E + APE + + K +D
Sbjct: 360 CENILLSSHFNVKLADFGFACACITESGEKYMSRTYCGSAAYAAPEIVYGAPYAPKVADA 539
Query: 431 WSFG 434
WS G
Sbjct: 540 WSLG 551
>31885
Length = 529
Score = 56.6 bits (135), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 44/170 (25%), Positives = 78/170 (45%), Gaps = 9/170 (5%)
Frame = -2
Query: 296 ANLMKQLQHQRLVRL-YAVVTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQ 354
+++ +L H LV L YA +E ++++ + G L ++ + K Q
Sbjct: 519 VDMLTRLDHPFLVNLWYAFQDEEDLFMVVDLFLGGDLRYHMQQEVSFREDCVKF--YLCQ 346
Query: 355 IAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWT 414
+A + ++ + +HRD++ NIL+ + C + DF +A +ED+E P +
Sbjct: 345 LALVLDYLRSQKIVHRDIKPDNILLDEQGHCHVTDFNIATQLEDDELATSTSGTRP--YM 172
Query: 415 APE----AIN----YGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEV 456
APE AIN YG D WS G+ L E++ R P+ +N +
Sbjct: 171 APEVYGVAINERRGYG---FPVDWWSLGVSLFELLKKRR-PFSVHSNTSL 34
>19094
Length = 898
Score = 55.5 bits (132), Expect = 6e-08, Method: Compositional matrix adjust.
Identities = 29/84 (34%), Positives = 45/84 (53%)
Frame = +1
Query: 357 EGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAP 416
+G+ ++ R IHRD++A NIL+++ K+ADFG+A + D P W AP
Sbjct: 91 KGL*YLHSRRKIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTPY-WMAP 267
Query: 417 EAINYGTFTIKSDVWSFGILLTEI 440
E I + +D+WS GI E+
Sbjct: 268 EVIQEIGYDCVADIWSLGITALEM 339
>21079
Length = 878
Score = 50.8 bits (120), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 38/137 (27%), Positives = 68/137 (49%), Gaps = 4/137 (2%)
Frame = +1
Query: 304 HQRLVRLY-AVVTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFI 362
H +L+ L+ A + ++ E++ G L + + + LT + QI G+ ++
Sbjct: 1 HPKLLMLWDAFEAPRTMVLVMEFVGAGELFERVIRDDFV-LTERDCVHFVRQICSGVGYM 177
Query: 363 EERNYIHRDLRAANIL-VSDTLS-CKIADFGLARLIE-DNEYTAREGAKFPIKWTAPEAI 419
++ +H DL+ N+L VSD + KI DFGLAR + + G ++ APE +
Sbjct: 178 HTQSILHLDLKPENVLCVSDNSNQIKIIDFGLARFYKPGDSLQVLFGTP---EFIAPEVV 348
Query: 420 NYGTFTIKSDVWSFGIL 436
NY +D+WS G++
Sbjct: 349 NYDEINFTTDMWSIGVI 399
>30755
Length = 1137
Score = 50.8 bits (120), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 37/142 (26%), Positives = 69/142 (48%), Gaps = 2/142 (1%)
Frame = +2
Query: 352 AAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEY--TAREGAKF 409
A+I + ++ + I+RDL+ N+L+ K+ADFGL + ED Y T +
Sbjct: 50 GAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCK--EDITYGRTTKTFCGT 223
Query: 410 PIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRP 469
P ++ APE ++ + D W G+++ E++ GR+P+ + +V+ L + P
Sbjct: 224 P-EYLAPEVLDDNDYGRAVDWWGTGVVMYEMIC-GRLPFYNRDH-DVLFTLILVEDVKFP 394
Query: 470 DNCPEELYQLMRLCWKERPEDR 491
N +E L+ + P +R
Sbjct: 395 RNITDEAKSLLSGLLAKDPRNR 460
>04138
Length = 800
Score = 49.7 bits (117), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 32/97 (32%), Positives = 47/97 (48%), Gaps = 7/97 (7%)
Frame = +1
Query: 357 EGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLAR-----LIEDNEYTAREGAKFPI 411
E + +I +HRD++AANIL++ K+ADFGLAR L + N YT R
Sbjct: 46 ERLYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNR----VVT 213
Query: 412 KWTAPEAINYG--TFTIKSDVWSFGILLTEIVTHGRI 446
W P + G ++ D W G ++ E+ T I
Sbjct: 214 LWYRPPELLLGDRNYSTAIDQWGAGCIMAEMWTRNPI 324
>13212
Length = 1067
Score = 48.9 bits (115), Expect = 5e-06, Method: Compositional matrix adjust.
Identities = 29/94 (30%), Positives = 49/94 (52%), Gaps = 8/94 (8%)
Frame = -1
Query: 354 QIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKF---P 410
++ + F+ + IHRD++A N+L++ K+ADFG++ N T ++ F P
Sbjct: 956 EMCMALDFLHRHHVIHRDIKAGNVLLTIDGEVKLADFGVSA---KNTQTQQKRDTFIGTP 786
Query: 411 IKWTAPEAINYGT-----FTIKSDVWSFGILLTE 439
W APE + T + K+D+WS G+ L E
Sbjct: 785 Y-WMAPEVVLCETLKDTPYDFKADIWSLGVTLIE 687
>09606
Length = 1300
Score = 48.9 bits (115), Expect = 5e-06, Method: Compositional matrix adjust.
Identities = 38/159 (23%), Positives = 67/159 (42%), Gaps = 21/159 (13%)
Frame = -3
Query: 315 TQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRA 374
T ++++ E GSL D L + T + D + G+ +I + DLR
Sbjct: 920 TSNHLWLVVELCTGGSLADILAQDHHLPET--SIRDFGIHLVTGLHYIHSLGILFHDLRP 747
Query: 375 ANILVSDTLSCKIADFGLARLIEDNEYT-----AREGAKFPIK----------------W 413
+ +L+ + K ADFGL+++ +N A G ++ I+ +
Sbjct: 746 SKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQWNIQSAEEMMKQVPTSGSPTY 567
Query: 414 TAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMT 452
APE +I SD+W+ G + E+ + G P+ G T
Sbjct: 566 MAPEVFQGAEPSIMSDLWALGCVFYEMFS-GHPPFLGET 453
>15910
Length = 1361
Score = 48.9 bits (115), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 34/114 (29%), Positives = 57/114 (50%), Gaps = 3/114 (2%)
Frame = +2
Query: 353 AQIAEGMAFIEERNYIHRDLRAANIL---VSDTLSCKIADFGLARLIEDNEYTAREGAKF 409
+ I G+ +I +HRDL+ N+L ++D K+ADFGL+R+IE E
Sbjct: 485 SDILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLADFGLSRIIEP-EVQMSTVCGT 661
Query: 410 PIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERG 463
P + APE + +T D+WS G+ + I+ G P+ E+ + + +G
Sbjct: 662 P-GYCAPEVLKGDKYTPSVDMWSVGV-IAYILLCGYEPFFAENEFEMYRKIIKG 817
>26711
Length = 405
Score = 46.6 bits (109), Expect = 2e-05, Method: Composition-based stats.
Identities = 33/111 (29%), Positives = 58/111 (52%), Gaps = 3/111 (2%)
Frame = -2
Query: 354 QIAEGMAFIEERNYIHRDLRAANILVS-DTL-SCKIADFGLAR-LIEDNEYTAREGAKFP 410
Q+ + + + + +H DL+ +N+L+S D L S ++ DFGLAR L E G
Sbjct: 392 QVLDILQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARKLYPPQETFLNHGTP-- 219
Query: 411 IKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLE 461
+T+PEA++ + SDVW G+ L I+ G+ P+ + E ++ +
Sbjct: 218 -GFTSPEALDVKPISTASDVWGVGV-LAYILLSGQSPFQADSATESLKKTQ 72
>35671
Length = 567
Score = 46.6 bits (109), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 18/47 (38%), Positives = 31/47 (65%)
Frame = -3
Query: 461 ERGYRMVRPDNCPEELYQLMRLCWKERPEDRPTFDYLRSVLEDFFTA 507
++G R+ +P +C +E Y++M CW E E+RPTF L V+E+ + +
Sbjct: 565 QKGNRLAKPISCTDEAYKVMLQCWTESREERPTFKKLVPVMENLYRS 425
>03240
Length = 1683
Score = 45.8 bits (107), Expect = 4e-05, Method: Compositional matrix adjust.
Identities = 56/246 (22%), Positives = 102/246 (41%), Gaps = 56/246 (22%)
Frame = -3
Query: 294 AEANLMKQLQHQRLVRLY-AVVTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLD-- 350
AE +++ + ++ +V+LY + +Y + +Y+ G L+ L I++ I LD
Sbjct: 1144 AERDILAEADNEWVVKLYYSFQDHNYLYFVMDYVPGGDLMGLL-----IRMEI---LDEP 989
Query: 351 ----MAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLA---RLIEDNEYTA 403
A++ + + + +IHRD++ NIL+ K+ DFGL R +++Y
Sbjct: 988 LARFYVAELVQAIESVHRMGFIHRDIKPDNILIDRNGHIKLTDFGLCTGFRWTHNSKYYQ 809
Query: 404 REGA-----KFPIK-----------------------------------WTAPEAIN-YG 422
R+G +K + APE ++ G
Sbjct: 808 RDGTHARQDSMEVKCQLDEQCQCEILKPLERRRKREQRCLAHSLVGTPNYIAPEVLSRLG 629
Query: 423 TFTIKSDVWSFGILLTEIVTHGRIPY----PGMTNPEVIQNLERGYRMVRPDNCPEELYQ 478
+T D WS G++L E++ G P+ P T +VI N + ++ R N +
Sbjct: 628 GYTSVCDWWSVGVILFEMLV-GHPPFYANTPAETQYKVI-NWKDMLKIPRESNLSQPAKD 455
Query: 479 L-MRLC 483
L +RLC
Sbjct: 454 LILRLC 437
>01392
Length = 1806
Score = 45.1 bits (105), Expect = 7e-05, Method: Compositional matrix adjust.
Identities = 35/118 (29%), Positives = 55/118 (46%), Gaps = 12/118 (10%)
Frame = -1
Query: 354 QIAEGMAFIEERNYIHRDLRAANIL---VSDTLSCKIADFGLARLIE-DNEYTAREGAKF 409
IA + F+ + HRDL+ NIL + D + KI DF LA I D + T
Sbjct: 1767 HIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGISCDGDGTKTPELLT 1588
Query: 410 PI---KWTAPEAINYG-----TFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQN 459
P+ ++ APE ++ ++ + D+WS GI+L I+ G P+ G + N
Sbjct: 1587 PVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILY-IMLCGYPPFYGQCGEDCGWN 1417
>19761
Length = 473
Score = 45.1 bits (105), Expect = 8e-05, Method: Compositional matrix adjust.
Identities = 32/127 (25%), Positives = 61/127 (48%), Gaps = 4/127 (3%)
Frame = -3
Query: 354 QIAEGMAFIEERN--YIHRDLRAANILVSDTLSCKIADFGLARLIED--NEYTAREGAKF 409
Q A + ++ +HRDL+ NI V++ ++ D GLAR + + T++ G
Sbjct: 399 QTASALNYMHTHTPVILHRDLKPQNIYVTEKGDVRLGDLGLARKLTGPADFATSQVGT-- 226
Query: 410 PIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRP 469
I + +PE ++ + KSD+WS G + +I G+ M ++ + G ++ P
Sbjct: 225 -IMYLSPEILSQQPYNSKSDIWSLGCVFYDIT--GKKGSDEMGVMFLLVQVMGGRKLPLP 55
Query: 470 DNCPEEL 476
D+ +E
Sbjct: 54 DHYSQEF 34
>37602
Length = 804
Score = 44.7 bits (104), Expect = 9e-05, Method: Compositional matrix adjust.
Identities = 22/79 (27%), Positives = 43/79 (54%)
Frame = -1
Query: 312 AVVTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRD 371
+ + +E ++I EY GS+ D LT ++ + + +G+ ++ R +HRD
Sbjct: 315 SYLRREKLWIAMEYCGGGSMQDIYHVTG--PLTEPQIAFVCRETLKGLHYLHRRGKMHRD 142
Query: 372 LRAANILVSDTLSCKIADF 390
++ ANIL+++ K+ADF
Sbjct: 141 IKGANILLTEEGDVKLADF 85
>26560
Length = 398
Score = 43.9 bits (102), Expect = 2e-04, Method: Composition-based stats.
Identities = 29/98 (29%), Positives = 51/98 (52%), Gaps = 1/98 (1%)
Frame = -1
Query: 352 AAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPI 411
AA++ G+ + R ++RDL+ ANIL+ + +I+D GLA A G
Sbjct: 338 AAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGLACDFSKKRPHASVGTH--- 168
Query: 412 KWTAPEAINYG-TFTIKSDVWSFGILLTEIVTHGRIPY 448
+ APE + G ++ +D +SFG +L +++ G P+
Sbjct: 167 GYMAPEVLMKGQSYDSSADWFSFGCMLYKLLK-GHSPF 57
>27405
Length = 532
Score = 42.0 bits (97), Expect = 5e-04, Method: Compositional matrix adjust.
Identities = 35/121 (28%), Positives = 55/121 (45%)
Frame = -3
Query: 311 YAVVTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHR 370
YA T E + I + M G L L + G+ T ++ AA++ G+ + R ++R
Sbjct: 353 YAFQTPEKLCFILDLMNGGDLHYHL-SQHGV-FTEKEVRFYAAEVMLGLEHMHSRFVVYR 180
Query: 371 DLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDV 430
DL+ ANIL+ + +I+D GLA + A G + APE + G S
Sbjct: 179 DLKPANILLDENGHVRISDLGLACDFSKKKPHASVGTH---GYMAPEVLMKGQAYDSSAD 9
Query: 431 W 431
W
Sbjct: 8 W 6
>21433
Length = 590
Score = 41.6 bits (96), Expect = 7e-04, Method: Compositional matrix adjust.
Identities = 25/89 (28%), Positives = 41/89 (46%)
Frame = +2
Query: 354 QIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKW 413
Q++ + + R IHRD++ N+L+ KIADFG + + T G + +
Sbjct: 191 QLSSALEYCHYRKVIHRDIKPENLLLGLKGDLKIADFGWSVHAPSSRRTTMCGT---LDY 361
Query: 414 TAPEAINYGTFTIKSDVWSFGILLTEIVT 442
PE + T D+WS G+L E +
Sbjct: 362 LPPEMVEGKTHDENVDLWSLGVLCYEFLV 448
>11185
Length = 473
Score = 41.6 bits (96), Expect = 8e-04, Method: Compositional matrix adjust.
Identities = 31/133 (23%), Positives = 56/133 (42%), Gaps = 21/133 (15%)
Frame = +1
Query: 350 DMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYT-----AR 404
D + G+ +I + DLR + +L+ + K ADFGL+++ +N A
Sbjct: 13 DFGIHLVTGLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAE 192
Query: 405 EGAKFPIK----------------WTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPY 448
G ++ I+ + APE +I SD+W+ G + E+ + R+
Sbjct: 193 AGDQWNIQSAEEMMKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSGSRL-- 366
Query: 449 PGMTNPEVIQNLE 461
+PE + LE
Sbjct: 367 SAKPSPEFLNLLE 405
>12786
Length = 460
Score = 40.0 bits (92), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 30/108 (27%), Positives = 52/108 (48%), Gaps = 22/108 (20%)
Frame = -3
Query: 368 IHRDLRAAN-ILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPI-KWTAPEAINYGT-- 423
IH DL+ AN +LV+ L K+ DFG+A ++ ++ + + ++ + +PEAI
Sbjct: 344 IHSDLKPANFMLVAGNL--KLIDFGIANTLQQDKTSVLKDSRVGTPSYMSPEAIMAACDD 171
Query: 424 ------------------FTIKSDVWSFGILLTEIVTHGRIPYPGMTN 453
++SDVWS G +L +V +GR P+ + N
Sbjct: 170 SADDSMEEDGHRTKPKYKVGVRSDVWSLGCILYNMV-YGRTPFQHIKN 30
>28638
Length = 1458
Score = 40.0 bits (92), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 31/111 (27%), Positives = 55/111 (49%), Gaps = 4/111 (3%)
Frame = -1
Query: 336 KTPSGIKLTINKLLDMAAQIAEGMAFIE--ERNYIHRDLRAANILVSD--TLSCKIADFG 391
+T G+ L + + A Q+ + F+ E N IH DL+ NIL+ + + KI DFG
Sbjct: 861 QTLEGVSLNLTR--KFAQQLCTALLFLATPEMNIIHCDLKPENILLCNPKRSAIKIVDFG 688
Query: 392 LARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVT 442
+ + Y + ++F + +PE + + + D+WS G +L E+ T
Sbjct: 687 SSCQLGQRIYQYIQ-SRF---YRSPEVLLGVPYDLAIDMWSLGCILVEMHT 547
>18481
Length = 437
Score = 39.7 bits (91), Expect = 0.003, Method: Composition-based stats.
Identities = 20/64 (31%), Positives = 36/64 (56%), Gaps = 3/64 (4%)
Frame = -1
Query: 342 KLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCK---IADFGLARLIED 398
+ T+ +L ++ Q+ + FI ++ +IHRDL+ N L+ C I DFGL++ +D
Sbjct: 209 RFTLKTILMVSDQLLSRLEFIHQKCFIHRDLKPDNFLMGLGRHCHRLYIIDFGLSKRYKD 30
Query: 399 NEYT 402
+ T
Sbjct: 29 TQGT 18
>32264
Length = 287
Score = 39.3 bits (90), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 18/45 (40%), Positives = 27/45 (60%)
Frame = +1
Query: 460 LERGYRMVRPDNCPEELYQLMRLCWKERPEDRPTFDYLRSVLEDF 504
+E GYR+ + P+ +Y+LM CW+ PE RP F L + L+D
Sbjct: 1 IEDGYRLQQNPQTPDSVYKLMLRCWEYVPEKRPHFKELYTSLKDI 135
>16708
Length = 1397
Score = 39.3 bits (90), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 16/45 (35%), Positives = 27/45 (60%)
Frame = -1
Query: 351 MAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARL 395
+A Q + I E +H D++A N+LV +CK+ D+G+A+L
Sbjct: 1079 IAGQXVCALEHIHELGVVHMDVKADNVLVDAHGNCKLTDYGIAQL 945
>17286
Length = 489
Score = 38.9 bits (89), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 17/49 (34%), Positives = 31/49 (63%)
Frame = +3
Query: 126 ALHSYEPSHDGDLGFEKGEQLRILEQSGEWWKAQSLTTGQEGFIPFNFV 174
A++ + P DG+LGF++G+ + ++ Q E W S+ G+ G+ P N+V
Sbjct: 36 AIYDFLPESDGELGFQEGDMITLISQVDENWFEGSV-HGKVGYFPINYV 179
>29243
Length = 1147
Score = 38.1 bits (87), Expect = 0.008, Method: Compositional matrix adjust.
Identities = 28/98 (28%), Positives = 46/98 (46%), Gaps = 2/98 (2%)
Frame = +2
Query: 172 NFVAKANSLEPEPWFFKNLSRKDAERQLLAPGNTHGSFLIRESES--TAGSFSLSVRDFD 229
++V + SLE W+ + R A++ L + G+FLIR + + G SLS++
Sbjct: 269 DYVNEPCSLESYNWYVGIMERPVAQKXLDTCPD--GTFLIRVTNNPLRRGELSLSIK--- 433
Query: 230 QNQGEVVKHYKIRNLDNGGFYISPRITFPGLHELVRHY 267
V+H K+ G FY++ F + LV HY
Sbjct: 434 --YANAVRHIKVNRNPQGRFYLADGRYFDNIQSLVDHY 541
>27287
Length = 514
Score = 37.0 bits (84), Expect = 0.017, Method: Compositional matrix adjust.
Identities = 15/43 (34%), Positives = 24/43 (55%)
Frame = -2
Query: 466 MVRPDNCPEELYQLMRLCWKERPEDRPTFDYLRSVLEDFFTAT 508
M +P E++ +M CW+E P DRP+F L L+ T++
Sbjct: 513 MKKPPYASSEMFGIMHSCWQEDPNDRPSFSRLVQELDKMLTSS 385
>21210
Length = 518
Score = 37.0 bits (84), Expect = 0.020, Method: Compositional matrix adjust.
Identities = 25/85 (29%), Positives = 42/85 (49%), Gaps = 3/85 (3%)
Frame = +3
Query: 416 PEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNP-EVIQNLERGYRMVRPDN--C 472
P A ++G + ++SDVWS GI L E+ T GR PY + + +Q + RG P +
Sbjct: 42 PRASSHG-YDVRSDVWSLGITLMELAT-GRFPYRKWVSIFDQLQQVVRGVAPCLPHDGAF 215
Query: 473 PEELYQLMRLCWKERPEDRPTFDYL 497
+ + C + + RP ++ L
Sbjct: 216 SHDFVNFVNKCLTKDEKQRPKYNKL 290
>32000
Length = 644
Score = 36.2 bits (82), Expect = 0.032, Method: Compositional matrix adjust.
Identities = 30/97 (30%), Positives = 48/97 (49%), Gaps = 3/97 (3%)
Frame = -1
Query: 382 TLSCKIADFGLARL--IEDNEYTAREGAKFPIKWTAPEAINYGTF-TIKSDVWSFGILLT 438
T KIADFGLAR+ + YT + + APE + F ++ D+WS G +
Sbjct: 581 TAKMKIADFGLARVFGLPVRTYTHEV---ITLWYRAPEILLGCRFYSVPVDIWSLGCIFV 411
Query: 439 EIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDNCPEE 475
E++T R +PG + +++ YR+ R P+E
Sbjct: 410 EMMTR-RALFPGDS------EIDQLYRIFRTLGTPDE 321
>07933
Length = 728
Score = 35.4 bits (80), Expect = 0.057, Method: Compositional matrix adjust.
Identities = 14/30 (46%), Positives = 16/30 (53%)
Frame = +3
Query: 469 PDNCPEELYQLMRLCWKERPEDRPTFDYLR 498
P+ CP LY +M CW P RPTF L
Sbjct: 3 PNYCPNLLYNIMMQCWSAEPSARPTFHKLE 92
>38046
Length = 446
Score = 34.7 bits (78), Expect = 0.11, Method: Composition-based stats.
Identities = 14/25 (56%), Positives = 20/25 (80%)
Frame = -1
Query: 355 IAEGMAFIEERNYIHRDLRAANILV 379
IA+ MA++E+ N+IHR+L NILV
Sbjct: 98 IADAMAYMEKENFIHRNLGDRNILV 24
>29590
Length = 320
Score = 33.9 bits (76), Expect = 0.16, Method: Composition-based stats.
Identities = 14/41 (34%), Positives = 27/41 (65%)
Frame = +3
Query: 413 WTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTN 453
+ APE ++Y +I++D+WS G+L ++T P+ G+T+
Sbjct: 72 YVAPEVLDYEPLSIQTDMWSLGVLSYVMLTACS-PFVGITS 191
>11228
Length = 2155
Score = 33.5 bits (75), Expect = 0.22, Method: Compositional matrix adjust.
Identities = 20/40 (50%), Positives = 25/40 (62%)
Frame = -1
Query: 185 WFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLS 224
W+ L R AE +LL + GS+L+RESES GSF LS
Sbjct: 1972 WYHGRLGRAGAE-ELLRDQDA-GSYLVRESESKLGSFVLS 1859
>37260
Length = 401
Score = 32.7 bits (73), Expect = 0.32, Method: Composition-based stats.
Identities = 19/69 (27%), Positives = 35/69 (50%)
Frame = -1
Query: 172 NFVAKANSLEPEPWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLSVRDFDQN 231
+F+ L+ W++ LS ++AE +L+ GSFL+R+S + SLS +
Sbjct: 221 DFLESMKQLKDCGWYWGPLSYEEAESKLM--DKRDGSFLVRDSSNENYILSLSFKSMGHV 48
Query: 232 QGEVVKHYK 240
++H+K
Sbjct: 47 HHTRIEHHK 21
>36481
Length = 806
Score = 32.7 bits (73), Expect = 0.38, Method: Compositional matrix adjust.
Identities = 27/112 (24%), Positives = 51/112 (45%), Gaps = 6/112 (5%)
Frame = +2
Query: 277 VAVKSLKQGSMSPDAFLAEANLMKQLQHQ------RLVRLYAVVTQEPIYIITEYMENGS 330
+A+K +K +A E N++++L+ + V++ I+ +M S
Sbjct: 446 IALKIIKNVDKYREAAKLEINVLEKLREKDPHAKHMCVQMLDWFDYHGHVCISFHMLGLS 625
Query: 331 LVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDT 382
+ DFLK S I ++ ++ Q+ + F+ E H DL+ NIL D+
Sbjct: 626 VFDFLKDNSYGAYPIEQVRHISYQLCYAVNFLHENQLTHTDLKPENILFVDS 781
>15741
Length = 402
Score = 32.3 bits (72), Expect = 0.53, Method: Composition-based stats.
Identities = 14/42 (33%), Positives = 20/42 (47%)
Frame = -3
Query: 337 TPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANIL 378
T + LT A +A GMA + +HRD+ A N+L
Sbjct: 127 TSTANDLTARDFFSFALHVARGMAHVANNKIVHRDVAARNVL 2
>06462
Length = 1511
Score = 30.8 bits (68), Expect = 1.3, Method: Compositional matrix adjust.
Identities = 17/48 (35%), Positives = 24/48 (50%)
Frame = +1
Query: 183 EPWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLSVRDFDQ 230
E W+ +SR++AE+ L G FL+RES F LS + Q
Sbjct: 1090 ELWYHGKMSRREAEKLL----GKDGDFLVRESGHNXSQFVLSGKHHGQ 1221
>13664
Length = 507
Score = 30.8 bits (68), Expect = 1.3, Method: Composition-based stats.
Identities = 14/45 (31%), Positives = 23/45 (51%)
Frame = +2
Query: 124 VIALHSYEPSHDGDLGFEKGEQLRILEQSGEWWKAQSLTTGQEGF 168
V+AL+ Y+ +L G+ + +L + E W L GQ+GF
Sbjct: 371 VVALYDYKAQRSDELTILSGDVIMLLHKDSESWWMGELLDGQQGF 505
>20131
Length = 574
Score = 30.8 bits (68), Expect = 1.4, Method: Compositional matrix adjust.
Identities = 15/53 (28%), Positives = 28/53 (52%), Gaps = 1/53 (1%)
Frame = -2
Query: 125 IALHSYEPSHDGDLGFEKGEQLRILEQSGEWWKAQSLTTGQE-GFIPFNFVAK 176
+A++SY DL F +G+ + + ++ +WW T G++ G P +V K
Sbjct: 471 VAMYSYVSGETADLTFNEGDMILVTKKDEDWWTG---TLGEKTGMFPSTYVKK 322
>17516
Length = 453
Score = 28.9 bits (63), Expect = 5.0, Method: Composition-based stats.
Identities = 27/104 (25%), Positives = 50/104 (48%), Gaps = 7/104 (6%)
Frame = -3
Query: 413 WTAPEAI-NYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRM-VRPD 470
+ APE + G + +K+DV+S I+L E+ +G+ +++ + LE + +RP
Sbjct: 421 YMAPEVLLQKGQYDMKADVYSLAIILWEL-WYGQDAADHISS-HLFGRLEDAVQAGLRPS 248
Query: 471 ---NC--PEELYQLMRLCWKERPEDRPTFDYLRSVLEDFFTATE 509
C P++ +L++ W+ RPT EDF T+
Sbjct: 247 VTMTCKPPDDWLKLLQSGWEFHASKRPTSRDAAEFFEDFLERTK 116
>30665
Length = 530
Score = 28.5 bits (62), Expect = 6.5, Method: Compositional matrix adjust.
Identities = 10/19 (52%), Positives = 17/19 (89%)
Frame = +3
Query: 319 IYIITEYMENGSLVDFLKT 337
++++TE+ ENGSL D+LK+
Sbjct: 441 LWLLTEFHENGSLSDYLKS 497
>18050
Length = 448
Score = 28.5 bits (62), Expect = 7.1, Method: Compositional matrix adjust.
Identities = 16/57 (28%), Positives = 29/57 (50%), Gaps = 1/57 (1%)
Frame = +3
Query: 124 VIALHSYEPSHDGDLGFEKGEQLRILEQSGE-WWKAQSLTTGQEGFIPFNFVAKANS 179
VIA HSYE L E G+ + + + + W++ + + G G+ P ++ + NS
Sbjct: 24 VIAKHSYESDEPDVLQLELGDVVNVSRKLPDGWYQGERIRDGAVGWFPGSYTEELNS 194
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000268509 | hsapiens_gene_ensembl | Katanin p80
WD40-containing subunit B1 (Katanin p80 subunit B1) (p80 katanin).
[Source:Uniprot/SWISSPROT;Acc:Q9BVA0]
(655 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
19949 282 2e-76
30256 113 2e-25
00561 100 2e-21
17598 97 1e-20
12806 92 5e-19
13335 90 3e-18
17602 85 9e-17
02147 82 1e-15
03156 80 2e-15
01327 80 3e-15
27465 79 4e-15
29912 78 1e-14
12574 75 8e-14
19498 67 2e-11
02960 65 7e-11
01805 65 1e-10
03395 65 1e-10
12960 64 1e-10
13278 64 1e-10
16199 54 1e-10
03387 64 2e-10
04088 63 3e-10
17266 63 5e-10
01768 60 3e-09
14555 44 5e-09
11493 59 6e-09
02090 59 6e-09
27270 57 2e-08
15118 56 4e-08
01462 55 6e-08
18981 55 7e-08
15780 55 1e-07
01249 55 1e-07
21105 54 2e-07
26939 54 2e-07
37180 52 1e-06
31864 50 4e-06
19863 50 4e-06
00825 49 6e-06
15337 49 9e-06
27806 49 9e-06
26107 47 2e-05
21921 47 2e-05
11915 47 2e-05
19140 46 4e-05
34005 46 4e-05
01598 46 5e-05
30295 45 7e-05
21960 43 3e-04
04358 42 7e-04
21763 42 9e-04
16105 42 9e-04
31384 41 0.002
10162 41 0.002
15745 41 0.002
14500 40 0.002
10264 40 0.002
31474 40 0.003
17298 40 0.003
15972 40 0.003
31118 40 0.004
25400 40 0.004
16436 39 0.005
02948 39 0.010
06799 37 0.019
37142 37 0.020
05642 37 0.022
20662 37 0.023
38177 37 0.029
04395 37 0.037
39204 36 0.049
07665 35 0.099
13890 35 0.13
05303 34 0.15
35695 34 0.15
04524 34 0.21
36111 33 0.25
25880 33 0.27
30108 33 0.40
27681 33 0.44
13486 33 0.52
30297 32 0.54
27475 32 0.65
07781 32 0.83
22113 31 1.6
12372 31 1.6
30176 31 1.8
20271 31 1.8
13509 30 2.4
31054 30 3.0
25930 29 4.7
30727 29 5.9
>19949
Length = 903
Score = 282 bits (722), Expect = 2e-76, Method: Compositional matrix adjust.
Identities = 136/284 (47%), Positives = 187/284 (65%), Gaps = 4/284 (1%)
Frame = +2
Query: 108 ICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAAD 167
+ SLDFHPYG + ASGS D N+KLWDIRRKGC++ Y+GH+ V CLRFSPDG+W+ASA++
Sbjct: 2 VKSLDFHPYGAYTASGSMDCNVKLWDIRRKGCIYTYKGHTGCVCCLRFSPDGRWIASASE 181
Query: 168 DHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCI 227
D VKLWDLTAGK++++ H VN +EFHP+E+LLASGS+DRT++FWDLE FQ++S
Sbjct: 182 DGLVKLWDLTAGKLLTDLKLHRDAVNTIEFHPHEFLLASGSADRTVKFWDLETFQLISTT 361
Query: 228 EGEPGPVRSVLFNPDGCCLYSGCQDSLRVYGWEPERCFDVVLVNWGKVADLAICNDQLIG 287
E E +RS+LF+PDG CLYSG +D+L+VY WEP +D V V WG+V D++I N QLIG
Sbjct: 362 EPEANSIRSILFHPDGVCLYSGSKDTLKVYHWEPLELYDTVSVPWGQVCDMSISNTQLIG 541
Query: 288 VAFSQSNVSSYVVDLTRVTRTGTVARDPVQDHRPLAQPLPNPSAPLRRIYERPST----T 343
+F ++NV+SYVVD+ +V+ G +++ R + L N I +RP T
Sbjct: 542 ASFYKTNVASYVVDIEKVSHIGKPTPSSLENRRE-STSLSNNRRSF--ITDRPPTQSTQQ 712
Query: 344 CSKPQRVKQNXXXXXXXXXXXXXXXXXXXXAEIQNAEDYNEIFQ 387
S P+R A+I+N +Y E+F+
Sbjct: 713 TSDPKRSDD--------PGEKSDDVEESSGADIRNPAEYRELFK 820
Score = 97.4 bits (241), Expect = 2e-20, Method: Compositional matrix adjust.
Identities = 48/142 (33%), Positives = 77/142 (54%)
Frame = +2
Query: 33 GRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDL 92
G A+G DC V LW I + CI + GHT V +R + I + S+ G +++WDL
Sbjct: 29 GAYTASGSMDCNVKLWDIRRKGCIYTYKGHTGCVCCLRFSPDGRWIASASEDGLVKLWDL 208
Query: 93 EAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRC 152
A K+L L H+ + +++FHP+ +ASGS D +K WD+ + + ++R
Sbjct: 209 TAGKLLTDLKLHRDAVNTIEFHPHEFLLASGSADRTVKFWDLETFQLISTTEPEANSIRS 388
Query: 153 LRFSPDGKWLASAADDHTVKLW 174
+ F PDG L S + D T+K++
Sbjct: 389 ILFHPDGVCLYSGSKD-TLKVY 451
>30256
Length = 961
Score = 113 bits (283), Expect = 2e-25, Method: Compositional matrix adjust.
Identities = 63/221 (28%), Positives = 120/221 (54%)
Frame = +3
Query: 13 LQEIVAHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLN 72
++ ++ H V S + +G + +G D + +W+ + C +L GH+S V + L+
Sbjct: 21 IKNLIGHTGGVWS---SQMTGNTVISGSTDRSLKVWNADTGVCTHTLYGHSSTVRCLSLS 191
Query: 73 TPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLW 132
+ +V+GS+ ++RVWD+E+ L L+GH A + + + G+ V SG+ D +++W
Sbjct: 192 GKK--VVSGSRDATLRVWDIESGHCLNVLLGHMAAVRCVQYD--GKRVVSGAXDYTVRVW 359
Query: 133 DIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPV 192
D C+ +GH+ V L+F DG ++ S + D ++++WD+ GK++ GH
Sbjct: 360 DPDTASCLHTLQGHTNRVYSLQF--DGVYVVSGSLDTSIRVWDVRCGKLVHTLMGHQSLT 533
Query: 193 NVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGP 233
+ +E N LL SG++D T++ WD+ + C++ GP
Sbjct: 534 SGLELKDN--LLVSGNADSTVKVWDVHTGK---CLQTLLGP 641
Score = 107 bits (266), Expect = 2e-23, Method: Compositional matrix adjust.
Identities = 68/209 (32%), Positives = 103/209 (49%), Gaps = 3/209 (1%)
Frame = +3
Query: 14 QEIVAHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNT 73
+ H+S V L L SG+ + +G D + +W I +C+ L GH + V V+ +
Sbjct: 144 HTLYGHSSTVRCLSL---SGKKVVSGSRDATLRVWDIESGHCLNVLLGHMAAVRCVQYDG 314
Query: 74 PEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWD 133
+V+G+ ++RVWD + A L TL GH + SL F G +V SGS DT+I++WD
Sbjct: 315 KR--VVSGAXDYTVRVWDPDTASCLHTLQGHTNRVYSLQFD--GVYVVSGSLDTSIRVWD 482
Query: 134 IRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPG---HTG 190
+R V GH L + L S D TVK+WD+ GK + G H
Sbjct: 483 VRCGKLVHTLMGHQSLTSGLELKDN--LLVSGNADSTVKVWDVHTGKCLQTLLGPNKHRS 656
Query: 191 PVNVVEFHPNEYLLASGSSDRTIRFWDLE 219
V ++F N+ + + S D T++ WDL
Sbjct: 657 AVTCLQF--NKKFVVTCSDDGTVKLWDLN 737
Score = 104 bits (259), Expect = 1e-22, Method: Compositional matrix adjust.
Identities = 67/216 (31%), Positives = 109/216 (50%), Gaps = 1/216 (0%)
Frame = +3
Query: 55 CIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFH 114
CI +L GHT V S ++ +++GS S++VW+ + TL GH + + L
Sbjct: 18 CIKNLIGHTGGVWSSQM--TGNTVISGSTDRSLKVWNADTGVCTHTLYGHSSTVRCLSLS 191
Query: 115 PYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLW 174
G+ V SGS+D +++WDI C+ GH AVRC+++ DGK + S A D+TV++W
Sbjct: 192 --GKKVVSGSRDATLRVWDIESGHCLNVLLGHMAAVRCVQY--DGKRVVSGAXDYTVRVW 359
Query: 175 DLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGPV 234
D + GHT V ++F + + SGS D +IR WD+ ++V + G
Sbjct: 360 DPDTASCLHTLQGHTNRVYSLQF--DGVYVVSGSLDTSIRVWDVRCGKLVHTLMGHQSLT 533
Query: 235 RSVLFNPDGCCLYSGCQDS-LRVYGWEPERCFDVVL 269
+ + L SG DS ++V+ +C +L
Sbjct: 534 SGLELKDN--LLVSGNADSTVKVWDVHTGKCLQTLL 635
Score = 97.8 bits (242), Expect = 1e-20, Method: Compositional matrix adjust.
Identities = 63/208 (30%), Positives = 107/208 (51%), Gaps = 8/208 (3%)
Frame = +3
Query: 13 LQEIVAHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLN 72
L ++ H + V + + G+ + +G D V +W + +C+ +L GHT+ V S++ +
Sbjct: 261 LNVLLGHMAAVRCV---QYDGKRVVSGAXDYTVRVWDPDTASCLHTLQGHTNRVYSLQFD 431
Query: 73 TPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLW 132
+V+GS SIRVWD+ K++ TLMGH++ L+ + SG+ D+ +K+W
Sbjct: 432 GV--YVVSGSLDTSIRVWDVRCGKLVHTLMGHQSLTSGLELKD--NLLVSGNADSTVKVW 599
Query: 133 DIRRKGCVFRYRG---HSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEF---- 185
D+ C+ G H AV CL+F+ K++ + +DD TVKLWDL G +
Sbjct: 600 DVHTGKCLQTLLGPNKHRSAVTCLQFNK--KFVVTCSDDGTVKLWDLNTGDFIRNLITLP 773
Query: 186 -PGHTGPVNVVEFHPNEYLLASGSSDRT 212
G G V + + + + A GS + T
Sbjct: 774 SGGSGGVVWRLRCNNTKMVCAVGSRNGT 857
>00561
Length = 1003
Score = 100 bits (250), Expect = 2e-21, Method: Compositional matrix adjust.
Identities = 62/203 (30%), Positives = 101/203 (49%), Gaps = 4/203 (1%)
Frame = -3
Query: 59 LTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGE 118
L GH+ + V L++ ++GS ++R+WDL A K R GH ++ S+ F
Sbjct: 878 LYGHSHFISDVVLSSDGNYALSGSWDQTLRLWDLAAGKTTRRFEGHTKDVLSVAFSADNR 699
Query: 119 FVASGSQDTNIKLWDIRRKGCVFRYR--GHSQAVRCLRFSPD--GKWLASAADDHTVKLW 174
+ SGS+D IKLW+ + C F + GH+ V C+RFSP+ + S D TVK+W
Sbjct: 698 QIVSGSRDKTIKLWNTLAE-CKFTIQEDGHTDWVSCVRFSPNHSNPIIVSCGWDRTVKVW 522
Query: 175 DLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGPV 234
+L K+ + GH G +N V P+ L SG D WDL + + +E +
Sbjct: 521 NLANCKLKNNHHGHNGYLNTVTVSPDGSLCTSGGKDSKALLWDLNDGKNLYTLEHN-DII 345
Query: 235 RSVLFNPDGCCLYSGCQDSLRVY 257
++ F+P+ L S++++
Sbjct: 344 NALCFSPNRYWLCVAYGPSIKIW 276
Score = 90.1 bits (222), Expect = 2e-18, Method: Compositional matrix adjust.
Identities = 56/187 (29%), Positives = 91/187 (48%), Gaps = 9/187 (4%)
Frame = -3
Query: 76 ELIVAGSQSGSIRVW------DLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNI 129
+ I++ S+ ++ VW D + L GH I + G + SGS D +
Sbjct: 971 DTIISASRDKTLIVWKLTRDEDTNYGYPQKRLYGHSHFISDVVLSSDGNYALSGSWDQTL 792
Query: 130 KLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWD-LTAGKMMSEFPGH 188
+LWD+ R+ GH++ V + FS D + + S + D T+KLW+ L K + GH
Sbjct: 791 RLWDLAAGKTTRRFEGHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTLAECKFTIQEDGH 612
Query: 189 TGPVNVVEFHPNEY--LLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVLFNPDGCCL 246
T V+ V F PN ++ S DRT++ W+L ++ + G G + +V +PDG
Sbjct: 611 TDWVSCVRFSPNHSNPIIVSCGWDRTVKVWNLANCKLKNNHHGHNGYLNTVTVSPDGSLC 432
Query: 247 YSGCQDS 253
SG +DS
Sbjct: 431 TSGGKDS 411
Score = 80.5 bits (197), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 60/217 (27%), Positives = 92/217 (42%), Gaps = 5/217 (2%)
Frame = -3
Query: 7 TKTAWKLQEIVAHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPV 66
T + + + H+ +S +VL + G +G D + LW + GHT V
Sbjct: 905 TNYGYPQKRLYGHSHFISDVVL-SSDGNYALSGSWDQTLRLWDLAAGKTTRRFEGHTKDV 729
Query: 67 ESVRLNTPEELIVAGSQSGSIRVWD-LEAAKILRTLMGHKANICSLDFHP--YGEFVASG 123
SV + IV+GS+ +I++W+ L K GH + + F P + S
Sbjct: 728 LSVAFSADNRQIVSGSRDKTIKLWNTLAECKFTIQEDGHTDWVSCVRFSPNHSNPIIVSC 549
Query: 124 SQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMS 183
D +K+W++ + GH+ + + SPDG S D LWDL GK +
Sbjct: 548 GWDRTVKVWNLANCKLKNNHHGHNGYLNTVTVSPDGSLCTSGGKDSKALLWDLNDGKNLY 369
Query: 184 EFPGHTGPVNVVEFHPNEYLL--ASGSSDRTIRFWDL 218
H +N + F PN Y L A G S I+ WDL
Sbjct: 368 TLE-HNDIINALCFSPNRYWLCVAYGPS---IKIWDL 270
>17598
Length = 875
Score = 97.4 bits (241), Expect = 1e-20, Method: Compositional matrix adjust.
Identities = 54/204 (26%), Positives = 101/204 (49%), Gaps = 4/204 (1%)
Frame = +1
Query: 58 SLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYG 117
+L GH+ V V L+ +++ S ++R+WD++ R + H + ++ F P
Sbjct: 106 TLQGHSHFVSDVSLSADSRYVLSSSWDATLRLWDIKKGNTTRRFISHTRDALAVAFSPDN 285
Query: 118 EFVASGSQDTNIKLWDIRRKGCVFRY--RGHSQAVRCLRFSPDGK--WLASAADDHTVKL 173
+ASG +D +K+W+ + C F H V C++F D K + SA+ D T+K+
Sbjct: 286 RQIASGGRDKALKIWNTVGE-CKFTVDANSHQDWVTCVKFHQDAKSPLVVSASMDKTIKV 462
Query: 174 WDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGP 233
WD + F GH +N ++ Y LASGS D + W+++ + I+ +
Sbjct: 463 WDNQTMTLKHTFVGHKTQINAIDLALKTYYLASGSKDGIVMTWNIQNGTFLGKIDCDC-E 639
Query: 234 VRSVLFNPDGCCLYSGCQDSLRVY 257
V +V F+P+ L+ G + ++++
Sbjct: 640 VNAVKFSPNKYWLFVGTSEGIQIW 711
Score = 78.6 bits (192), Expect = 8e-15, Method: Compositional matrix adjust.
Identities = 52/194 (26%), Positives = 86/194 (44%), Gaps = 14/194 (7%)
Frame = +1
Query: 75 EELIVAGSQSGSIRVWDLEAAKI----------LRTLMGHKANICSLDFHPYGEFVASGS 124
+E ++ G + + VWDL K RTL GH + + +V S S
Sbjct: 1 KEFLIXGGRDKLLIVWDLVPRKDGDEDETWGGPRRTLQGHSHFVSDVSLSADSRYVLSSS 180
Query: 125 QDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAG--KMM 182
D ++LWDI++ R+ H++ + FSPD + +AS D +K+W+ T G K
Sbjct: 181 WDATLRLWDIKKGNTTRRFISHTRDALAVAFSPDNRQIASGGRDKALKIWN-TVGECKFT 357
Query: 183 SEFPGHTGPVNVVEFHPNEY--LLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVLFN 240
+ H V V+FH + L+ S S D+TI+ WD + + G + ++
Sbjct: 358 VDANSHQDWVTCVKFHQDAKSPLVVSASMDKTIKVWDNQTMTLKHTFVGHKTQINAIDLA 537
Query: 241 PDGCCLYSGCQDSL 254
L SG +D +
Sbjct: 538 LKTYYLASGSKDGI 579
Score = 77.8 bits (190), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 55/217 (25%), Positives = 93/217 (42%), Gaps = 3/217 (1%)
Frame = +1
Query: 18 AHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEEL 77
H+ VS + L A R + + D + LW I K N HT +V +
Sbjct: 115 GHSHFVSDVSLS-ADSRYVLSSSWDATLRLWDIKKGNTTRRFISHTRDALAVAFSPDNRQ 291
Query: 78 IVAGSQSGSIRVWD-LEAAKILRTLMGHKANICSLDFHPYGE--FVASGSQDTNIKLWDI 134
I +G + ++++W+ + K H+ + + FH + V S S D IK+WD
Sbjct: 292 IASGGRDKALKIWNTVGECKFTVDANSHQDWVTCVKFHQDAKSPLVVSASMDKTIKVWDN 471
Query: 135 RRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNV 194
+ + GH + + + +LAS + D V W++ G + + VN
Sbjct: 472 QTMTLKHTFVGHKTQINAIDLALKTYYLASGSKDGIVMTWNIQNGTFLGKIDCDC-EVNA 648
Query: 195 VEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEP 231
V+F PN+Y L G+S+ I+ WDL + + I P
Sbjct: 649 VKFSPNKYWLFVGTSE-GIQIWDLPNQKKIKDIRASP 756
>12806
Length = 961
Score = 92.4 bits (228), Expect = 5e-19, Method: Compositional matrix adjust.
Identities = 53/214 (24%), Positives = 106/214 (49%), Gaps = 8/214 (3%)
Frame = +3
Query: 58 SLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYG 117
+LTGH+ + + L+ ++ S ++R+WD++ + H ++ ++ F P
Sbjct: 150 TLTGHSHFISDLALSADSRFALSSSWDATLRLWDIKKGSTTSRFINHTRDVLTVAFSPDN 329
Query: 118 EFVASGSQDTNIKLWDIRRKGCVFRY--RGHSQAVRCLRFSPDGK--WLASAADDHTVKL 173
+ASG +D N+K+W+I + C + H+ V C+RF D K + SA++D T+K+
Sbjct: 330 RQIASGGRDKNLKIWNIMGE-CKYTVDANAHTDWVTCVRFHQDTKNPIVVSASNDKTIKV 506
Query: 174 WDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGP 233
WD + + F GH + ++ N L SGS D W++ + V I+ +
Sbjct: 507 WDNHTMTLKNTFVGHKAQITALDMSTN--YLVSGSKDGIAMTWNVAEGSFVGKIDCDD-Q 677
Query: 234 VRSVLFNPDG----CCLYSGCQDSLRVYGWEPER 263
+ ++ FN + L+ G Q+ ++++ + E+
Sbjct: 678 INAIKFNIENNKKKVWLFIGTQNGIQIWDYSGEK 779
Score = 85.5 bits (210), Expect = 6e-17, Method: Compositional matrix adjust.
Identities = 63/241 (26%), Positives = 106/241 (43%), Gaps = 13/241 (5%)
Frame = +3
Query: 67 ESVRLNTPEELIVAGSQSGSIRVWDLEAAKI----------LRTLMGHKANICSLDFHPY 116
E V + +++G + +I VWDL K +TL GH I L
Sbjct: 21 EQVVDGATKPFLISGGRDNNIIVWDL*PKKDGDEDQTWGVPRKTLTGHSHFISDLALSAD 200
Query: 117 GEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDL 176
F S S D ++LWDI++ R+ H++ V + FSPD + +AS D +K+W++
Sbjct: 201 SRFALSSSWDATLRLWDIKKGSTTSRFINHTRDVLTVAFSPDNRQIASGGRDKNLKIWNI 380
Query: 177 TAG-KMMSEFPGHTGPVNVVEFHPNEY--LLASGSSDRTIRFWDLEKFQVVSCIEGEPGP 233
K + HT V V FH + ++ S S+D+TI+ WD + + G
Sbjct: 381 MGECKYTVDANAHTDWVTCVRFHQDTKNPIVVSASNDKTIKVWDNHTMTLKNTFVGHKAQ 560
Query: 234 VRSVLFNPDGCCLYSGCQDSLRVYGWEPERCFDVVLVNWGKVADLAICNDQLIGVAFSQS 293
+ ++ + + L SG +D + + E F GK+ C+DQ+ + F+
Sbjct: 561 ITALDMSTN--YLVSGSKDGIAMTWNVAEGSFV------GKID----CDDQINAIKFNIE 704
Query: 294 N 294
N
Sbjct: 705 N 707
>13335
Length = 863
Score = 89.7 bits (221), Expect = 3e-18, Method: Compositional matrix adjust.
Identities = 60/215 (27%), Positives = 96/215 (44%), Gaps = 24/215 (11%)
Frame = +1
Query: 64 SPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASG 123
S + + + +V+GS +I +W++ K++R+ +GH+ ++ +L + P G ++ SG
Sbjct: 64 SSIRVCKFSPSSSHLVSGSDDDTICMWEVATQKLVRSYVGHEDSVMALAYSPNGHYLVSG 243
Query: 124 SQDTNIKLWDIRRKGC---VFRYRGHSQAVRCLRFSPD------------GKWLASAADD 168
S + ++ +WD C R H V C FSP LA+ D
Sbjct: 244 SPNGDLYVWDASFGHCRHLTLRVDAHDLGVTCCEFSPTFGTACAENSSTCNLLLATGGKD 423
Query: 169 HTVKLWDLTAGKMMSE--------FPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEK 220
+ +KLW +A E GH+ V F P+ LLASGS D+++R WD K
Sbjct: 424 NLIKLWTFSAQVGSPEVTLQCRDILSGHSDLVMACAFSPSSALLASGSFDKSVRLWDSVK 603
Query: 221 FQVVSCIEG-EPGPVRSVLFNPDGCCLYSGCQDSL 254
+ IE V F+ DG L SG D +
Sbjct: 604 GVALFSIEACHSRFVTCCAFSIDGTLLASGSMDRI 708
Score = 79.0 bits (193), Expect = 5e-15, Method: Compositional matrix adjust.
Identities = 59/207 (28%), Positives = 86/207 (41%), Gaps = 24/207 (11%)
Frame = +1
Query: 36 LATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAA 95
L +G DD + +W + + S GH V ++ + +V+GS +G + VWD
Sbjct: 106 LVSGSDDDTICMWEVATQKLVRSYVGHEDSVMALAYSPNGHYLVSGSPNGDLYVWDASFG 285
Query: 96 KILRTLM---GHKANICSLDFHP-YGE-----------FVASGSQDTNIKLWDIRRK--- 137
+ H + +F P +G +A+G +D IKLW +
Sbjct: 286 HCRHLTLRVDAHDLGVTCCEFSPTFGTACAENSSTCNLLLATGGKDNLIKLWTFSAQVGS 465
Query: 138 -----GCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAG-KMMSEFPGHTGP 191
C GHS V FSP LAS + D +V+LWD G + S H+
Sbjct: 466 PEVTLQCRDILSGHSDLVMACAFSPSSALLASGSFDKSVRLWDSVKGVALFSIEACHSRF 645
Query: 192 VNVVEFHPNEYLLASGSSDRTIRFWDL 218
V F + LLASGS DR I+ W L
Sbjct: 646 VTCCAFSIDGTLLASGSMDRIIKIWKL 726
Score = 65.5 bits (158), Expect = 7e-11, Method: Compositional matrix adjust.
Identities = 51/196 (26%), Positives = 79/196 (40%), Gaps = 25/196 (12%)
Frame = +1
Query: 87 IRVWDLEAAKILRTLM-GHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRG 145
+ VWD++ I K++I F P + SGS D I +W++ + V Y G
Sbjct: 4 VIVWDVKTGSIKGEYQHASKSSIRVCKFSPSSSHLVSGSDDDTICMWEVATQKLVRSYVG 183
Query: 146 HSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAG---KMMSEFPGHTGPVNVVEFHPN-- 200
H +V L +SP+G +L S + + + +WD + G + H V EF P
Sbjct: 184 HEDSVMALAYSPNGHYLVSGSPNGDLYVWDASFGHCRHLTLRVDAHDLGVTCCEFSPTFG 363
Query: 201 ----------EYLLASGSSDRTIRFWDLEK--------FQVVSCIEGEPGPVRSVLFNPD 242
LLA+G D I+ W Q + G V + F+P
Sbjct: 364 TACAENSSTCNLLLATGGKDNLIKLWTFSAQVGSPEVTLQCRDILSGHSDLVMACAFSPS 543
Query: 243 GCCLYSGCQD-SLRVY 257
L SG D S+R++
Sbjct: 544 SALLASGSFDKSVRLW 591
Score = 59.3 bits (142), Expect = 5e-09, Method: Compositional matrix adjust.
Identities = 43/143 (30%), Positives = 65/143 (45%), Gaps = 9/143 (6%)
Frame = +1
Query: 44 RVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAA-------- 95
RV+ + C S T T+ E+ +T L+ G + I++W A
Sbjct: 307 RVDAHDLGVTCCEFSPTFGTACAENS--STCNLLLATGGKDNLIKLWTFSAQVGSPEVTL 480
Query: 96 KILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRG-HSQAVRCLR 154
+ L GH + + F P +ASGS D +++LWD + +F HS+ V C
Sbjct: 481 QCRDILSGHSDLVMACAFSPSSALLASGSFDKSVRLWDSVKGVALFSIEACHSRFVTCCA 660
Query: 155 FSPDGKWLASAADDHTVKLWDLT 177
FS DG LAS + D +K+W LT
Sbjct: 661 FSIDGTLLASGSMDRIIKIWKLT 729
Score = 28.9 bits (63), Expect = 6.0, Method: Compositional matrix adjust.
Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 4/76 (5%)
Frame = +1
Query: 21 SNVSSLVLGKA---SGRLLATGGDDCRVNLWSINKPNCIMSLTG-HTSPVESVRLNTPEE 76
S S LV+ A S LLA+G D V LW K + S+ H+ V +
Sbjct: 499 SGHSDLVMACAFSPSSALLASGSFDKSVRLWDSVKGVALFSIEACHSRFVTCCAFSIDGT 678
Query: 77 LIVAGSQSGSIRVWDL 92
L+ +GS I++W L
Sbjct: 679 LLASGSMDRIIKIWKL 726
>17602
Length = 481
Score = 85.1 bits (209), Expect = 9e-17, Method: Compositional matrix adjust.
Identities = 42/134 (31%), Positives = 70/134 (52%), Gaps = 4/134 (2%)
Frame = +3
Query: 47 LWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLM-GHK 105
+W + C+ +L H+ PV +V N LIV+ S G R+WD + + L TL+
Sbjct: 6 IWDVKTGKCLKTLPAHSDPVTAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLXTLIDDDN 185
Query: 106 ANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCL--RFS-PDGKWL 162
+ + F P G+++ + + D +KLWD + C+ Y GH C+ FS GKW+
Sbjct: 186 PPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYVGHRNEKYCIFANFSVTGGKWI 365
Query: 163 ASAADDHTVKLWDL 176
S ++D+ V +W+L
Sbjct: 366 VSGSEDNMVYIWNL 407
Score = 72.0 bits (175), Expect = 8e-13, Method: Compositional matrix adjust.
Identities = 39/135 (28%), Positives = 68/135 (50%), Gaps = 4/135 (2%)
Frame = +3
Query: 88 RVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRY-RGH 146
R+WD++ K L+TL H + ++ F+ G + S S D ++WD C+
Sbjct: 3 RIWDVKTGKCLKTLPAHSDPVTAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLXTLIDDD 182
Query: 147 SQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFH---PNEYL 203
+ V ++FSP+GK++ +A D+T+KLWD + GK + + GH + +
Sbjct: 183 NPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYVGHRNEKYCIFANFSVTGGKW 362
Query: 204 LASGSSDRTIRFWDL 218
+ SGS D + W+L
Sbjct: 363 IVSGSEDNMVYIWNL 407
Score = 53.5 bits (127), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 28/96 (29%), Positives = 50/96 (52%), Gaps = 2/96 (2%)
Frame = +3
Query: 172 KLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVV-SCIEGE 230
++WD+ GK + P H+ PV V F+ + L+ S S D R WD Q + + I+ +
Sbjct: 3 RIWDVKTGKCLKTLPAHSDPVTAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLXTLIDDD 182
Query: 231 PGPVRSVLFNPDGCCLYSGCQD-SLRVYGWEPERCF 265
PV V F+P+G + + D +L+++ + +C
Sbjct: 183 NPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCL 290
Score = 52.0 bits (123), Expect = 8e-07, Method: Compositional matrix adjust.
Identities = 37/153 (24%), Positives = 74/153 (48%), Gaps = 7/153 (4%)
Frame = +3
Query: 8 KTAWKLQEIVAHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSP-V 66
KT L+ + AH+ V+++ + G L+ + D +W C+ +L +P V
Sbjct: 18 KTGKCLKTLPAHSDPVTAVHFNR-DGSLIVSSSYDGLCRIWDTASGQCLXTLIDDDNPPV 194
Query: 67 ESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPY----GEFVAS 122
V+ + + I+A + ++++WD K L+T +GH+ + F + G+++ S
Sbjct: 195 SFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYVGHRNEKYCI-FANFSVTGGKWIVS 371
Query: 123 GSQDTNIKLWDIRRKGCVFRYRGHSQ--AVRCL 153
GS+D + +W++ +G G + AV CL
Sbjct: 372 GSEDNMVYIWNLLDQGDSTEATGSHRRGAVLCL 470
>02147
Length = 1547
Score = 81.6 bits (200), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 60/245 (24%), Positives = 101/245 (41%), Gaps = 41/245 (16%)
Frame = +2
Query: 54 NCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDF 113
+ I + GH V LN G+ S ++WD E + L+T HK + S+DF
Sbjct: 146 DWIGTFEGHKGAVWGATLNREATRAATGAADFSAKIWDAEKGEELQTF-SHKHIVKSVDF 322
Query: 114 HPYGEFVASGSQDTNIKLWDIRRKGCVFR-YRGHSQAVRCLRFSPDGKWLASAADDHTVK 172
G + +GS + +K++D+ + + GH+ ++ F DGK + SA+DD TV+
Sbjct: 323 SHDGTALLTGSNEKLLKVFDLVNTDAEPKSFAGHTSNIKGALFLSDGKRIISASDDKTVR 502
Query: 173 LWDLTAGKMMSEFPGHT---------------------------------------GPVN 193
LW L + + + T P++
Sbjct: 503 LWSLETCQEVQQLTFDTPPTSLTLSPDKNTIIVTHSQNIAFYQADTLREMKKFEAEAPIS 682
Query: 194 VVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVLFNPDGCCLYSGCQD- 252
H +E +G D + +D E + + +G GPV V F+PDG SG +D
Sbjct: 683 SASLHQSERFFVAGGEDFKMYKFDYETGKEIESFKGHFGPVHCVRFSPDGELYASGSEDG 862
Query: 253 SLRVY 257
+LR++
Sbjct: 863 TLRLW 877
Score = 73.6 bits (179), Expect = 3e-13, Method: Compositional matrix adjust.
Identities = 46/167 (27%), Positives = 81/167 (48%)
Frame = +2
Query: 14 QEIVAHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNT 73
+ H SN+ L + G+ + + DD V LWS+ + LT T P S+ L +
Sbjct: 407 KSFAGHTSNIKG-ALFLSDGKRIISASDDKTVRLWSLETCQEVQQLTFDTPPT-SLTL-S 577
Query: 74 PEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWD 133
P++ + + S +I + + + ++ +A I S H F +G +D + +D
Sbjct: 578 PDKNTIIVTHSQNIAFYQADTLREMKKFEA-EAPISSASLHQSERFFVAGGEDFKMYKFD 754
Query: 134 IRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGK 180
+ ++GH V C+RFSPDG+ AS ++D T++LW T G+
Sbjct: 755 YETGKEIESFKGHFGPVHCVRFSPDGELYASGSEDGTLRLWQTTIGR 895
Score = 65.9 bits (159), Expect = 5e-11, Method: Compositional matrix adjust.
Identities = 57/239 (23%), Positives = 92/239 (38%), Gaps = 40/239 (16%)
Frame = +2
Query: 18 AHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEEL 77
H V L + + R ATG D +W K + + + H V+SV +
Sbjct: 167 GHKGAVWGATLNREATRA-ATGAADFSAKIWDAEKGEELQTFS-HKHIVKSVDFSHDGTA 340
Query: 78 IVAGSQSGSIRVWDLEAAKIL-RTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRR 136
++ GS ++V+DL ++ GH +NI F G+ + S S D ++LW +
Sbjct: 341 LLTGSNEKLLKVFDLVNTDAEPKSFAGHTSNIKGALFLSDGKRIISASDDKTVRLWSLET 520
Query: 137 KGCVFRYR-------------------GHSQAVRCL---------RFSPDG--------- 159
V + HSQ + +F +
Sbjct: 521 CQEVQQLTFDTPPTSLTLSPDKNTIIVTHSQNIAFYQADTLREMKKFEAEAPISSASLHQ 700
Query: 160 --KWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFW 216
++ + +D + +D GK + F GH GPV+ V F P+ L ASGS D T+R W
Sbjct: 701 SERFFVAGGEDFKMYKFDYETGKEIESFKGHFGPVHCVRFSPDGELYASGSEDGTLRLW 877
Score = 45.1 bits (105), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 39/165 (23%), Positives = 70/165 (42%), Gaps = 3/165 (1%)
Frame = +2
Query: 143 YRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEY 202
+ GH AV + + A+ A D + K+WD G+ + F H V V+F +
Sbjct: 161 FEGHKGAVWGATLNREATRAATGAADFSAKIWDAEKGEELQTFS-HKHIVKSVDFSHDGT 337
Query: 203 LLASGSSDRTIRFWDLEKFQVV-SCIEGEPGPVRSVLFNPDGCCLYSGCQD-SLRVYGWE 260
L +GS+++ ++ +DL G ++ LF DG + S D ++R+ W
Sbjct: 338 ALLTGSNEKLLKVFDLVNTDAEPKSFAGHTSNIKGALFLSDGKRIISASDDKTVRL--WS 511
Query: 261 PERCFDVVLVNWGK-VADLAICNDQLIGVAFSQSNVSSYVVDLTR 304
E C +V + + L + D+ + N++ Y D R
Sbjct: 512 LETCQEVQQLTFDTPPTSLTLSPDKNTIIVTHSQNIAFYQADTLR 646
Score = 38.5 bits (88), Expect = 0.008, Method: Compositional matrix adjust.
Identities = 25/90 (27%), Positives = 40/90 (44%)
Frame = +2
Query: 179 GKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVL 238
G + F GH G V + A+G++D + + WD EK + + V+SV
Sbjct: 143 GDWIGTFEGHKGAVWGATLNREATRAATGAADFSAKIWDAEKGEELQTFS-HKHIVKSVD 319
Query: 239 FNPDGCCLYSGCQDSLRVYGWEPERCFDVV 268
F+ DG L +G + L + FD+V
Sbjct: 320 FSHDGTALLTGSNEKLL-------KVFDLV 388
>03156
Length = 1014
Score = 80.5 bits (197), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 56/261 (21%), Positives = 110/261 (42%), Gaps = 10/261 (3%)
Frame = +1
Query: 18 AHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEEL 77
H ++ + G + + + D + +W + I GH V ++ LNT L
Sbjct: 49 GHDREITKVCYGASCNGMFSASRDK-TIKMWQRGNSHSIRDFIGHDMVVTAIHLNTDNTL 225
Query: 78 IVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRK 137
+ +GS+ ++R+WD+E LR + + + + P + +D ++++D R
Sbjct: 226 LCSGSRDNTVRIWDVETGACLRQNNIPQNLVTDVKWLPGSHLIIQAGEDKEVRIYDSRTL 405
Query: 138 GCVFRYRGHSQAVRCLRFSPDGKWLASAADDH-----TVKLWDLTAGKMMSEFPGHTGPV 192
G V + + DG++ + ++ LW L+ G + +EF GH +
Sbjct: 406 GIVRSFTKKQYIQMSCDVTADGQFCLTCSNGFGGNGCEATLWQLSDGSIQNEFKGHREAI 585
Query: 193 NVVEFHPNEY---LLASGSSDRTIRFWDLEKFQVV--SCIEGEPGPVRSVLFNPDGCCLY 247
F P+ L+A+ S D ++R W++ + V EG GP+ S++ DG L
Sbjct: 586 EACLFLPSNQDMTLIATASRDCSVRVWNMFTKECVCEQNFEG-TGPLTSMIAYGDGSVLV 762
Query: 248 SGCQDSLRVYGWEPERCFDVV 268
++V + D+V
Sbjct: 763 GTFNLGVQVMSLNGQSSLDIV 825
Score = 53.5 bits (127), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 24/78 (30%), Positives = 40/78 (51%)
Frame = +1
Query: 142 RYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNE 201
R+ GH + + + + + SA+ D T+K+W + +F GH V + + +
Sbjct: 40 RWTGHDREITKVCYGASCNGMFSASRDKTIKMWQRGNSHSIRDFIGHDMVVTAIHLNTDN 219
Query: 202 YLLASGSSDRTIRFWDLE 219
LL SGS D T+R WD+E
Sbjct: 220 TLLCSGSRDNTVRIWDVE 273
Score = 32.3 bits (72), Expect = 0.62, Method: Compositional matrix adjust.
Identities = 21/88 (23%), Positives = 38/88 (43%), Gaps = 1/88 (1%)
Frame = +1
Query: 179 GKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVL 238
G++ + GH + V + + + S S D+TI+ W + G V ++
Sbjct: 25 GRLEDRWTGHDREITKVCYGASCNGMFSASRDKTIKMWQRGNSHSIRDFIGHDMVVTAIH 204
Query: 239 FNPDGCCLYSGCQD-SLRVYGWEPERCF 265
N D L SG +D ++R++ E C
Sbjct: 205 LNTDNTLLCSGSRDNTVRIWDVETGACL 288
>01327
Length = 2215
Score = 80.1 bits (196), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 56/262 (21%), Positives = 110/262 (41%), Gaps = 10/262 (3%)
Frame = +3
Query: 17 VAHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEE 76
H ++ + G + + + D + +W + I GH V ++ LNT
Sbjct: 156 TGHDREITKVCYGASCNGMFSASRDK-TIKMWQRGNSHSIRDFIGHDMVVTAIHLNTDNT 332
Query: 77 LIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRR 136
L+ +GS+ ++R+WD+E LR + + + + P + +D ++++D R
Sbjct: 333 LLCSGSRDNTVRIWDVETGACLRQNNIPQNLVTDVKWLPGSHLIIQAGEDKEVRIYDSRT 512
Query: 137 KGCVFRYRGHSQAVRCLRFSPDGKWLASAADDH-----TVKLWDLTAGKMMSEFPGHTGP 191
G V + + DG++ + ++ LW L+ G + +EF GH
Sbjct: 513 LGIVRSFTKKQYIQMSCDVTADGQFCLTCSNGFGGNGCEATLWQLSDGSIQNEFKGHREA 692
Query: 192 VNVVEFHPNEY---LLASGSSDRTIRFWDLEKFQVV--SCIEGEPGPVRSVLFNPDGCCL 246
+ F P+ L+A+ S D ++R W++ + V EG GP+ S++ DG L
Sbjct: 693 IEACLFLPSNQDMTLIATASRDCSVRVWNMFTKECVCEQNFEG-TGPLTSMIAYGDGSVL 869
Query: 247 YSGCQDSLRVYGWEPERCFDVV 268
++V + D+V
Sbjct: 870 VGTFNLGVQVMSLNGQSSLDIV 935
Score = 61.6 bits (148), Expect = 9e-10, Method: Compositional matrix adjust.
Identities = 34/148 (22%), Positives = 67/148 (45%)
Frame = +3
Query: 77 LIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRR 136
L ++GS+ S+ ++D + ++ GH I + + + S S+D IK+W
Sbjct: 81 LCLSGSKDKSVVLYDYQNGRLEDRWTGHDREITKVCYGASCNGMFSASRDKTIKMWQRGN 260
Query: 137 KGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVE 196
+ + GH V + + D L S + D+TV++WD+ G + + V V+
Sbjct: 261 SHSIRDFIGHDMVVTAIHLNTDNTLLCSGSRDNTVRIWDVETGACLRQNNIPQNLVTDVK 440
Query: 197 FHPNEYLLASGSSDRTIRFWDLEKFQVV 224
+ P +L+ D+ +R +D +V
Sbjct: 441 WLPGSHLIIQAGEDKEVRIYDSRTLGIV 524
Score = 40.4 bits (93), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 26/103 (25%), Positives = 46/103 (44%), Gaps = 1/103 (0%)
Frame = +3
Query: 164 SAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQV 223
S + D +V L+D G++ + GH + V + + + S S D+TI+ W
Sbjct: 90 SGSKDKSVVLYDYQNGRLEDRWTGHDREITKVCYGASCNGMFSASRDKTIKMWQRGNSHS 269
Query: 224 VSCIEGEPGPVRSVLFNPDGCCLYSGCQD-SLRVYGWEPERCF 265
+ G V ++ N D L SG +D ++R++ E C
Sbjct: 270 IRDFIGHDMVVTAIHLNTDNTLLCSGSRDNTVRIWDVETGACL 398
>27465
Length = 658
Score = 79.3 bits (194), Expect = 4e-15, Method: Compositional matrix adjust.
Identities = 38/119 (31%), Positives = 63/119 (52%), Gaps = 1/119 (0%)
Frame = -1
Query: 59 LTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDF-HPYG 117
L H P+ +V N + GS + ++WD +A+ L TL GH+ + ++ F +P+G
Sbjct: 373 LRAHILPLTNVAFNKSGSSFITGSYDRTCKIWDTASAEELHTLEGHRNVVYAIAFNNPFG 194
Query: 118 EFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDL 176
+ V +GS D KLW C RGH+ + C+ F+P +A+ + D T +LWD+
Sbjct: 193 DKVITGSFDKTCKLWSTADGKCYHTLRGHTAEIVCVSFNPSSTLIATGSMDTTCRLWDV 17
Score = 75.9 bits (185), Expect = 5e-14, Method: Compositional matrix adjust.
Identities = 41/127 (32%), Positives = 61/127 (48%), Gaps = 1/127 (0%)
Frame = -1
Query: 97 ILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFS 156
+ + L H + ++ F+ G +GS D K+WD + GH V + F+
Sbjct: 385 LFKVLRAHILPLTNVAFNKSGSSFITGSYDRTCKIWDTASAEELHTLEGHRNVVYAIAFN 206
Query: 157 -PDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRF 215
P G + + + D T KLW GK GHT + V F+P+ L+A+GS D T R
Sbjct: 205 NPFGDKVITGSFDKTCKLWSTADGKCYHTLRGHTAEIVCVSFNPSSTLIATGSMDTTCRL 26
Query: 216 WDLEKFQ 222
WD+EK Q
Sbjct: 25 WDVEKAQ 5
Score = 66.6 bits (161), Expect = 3e-11, Method: Compositional matrix adjust.
Identities = 35/120 (29%), Positives = 58/120 (48%), Gaps = 1/120 (0%)
Frame = -1
Query: 18 AHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTP-EE 76
AH ++++ K SG TG D +W + +L GH + V ++ N P +
Sbjct: 367 AHILPLTNVAFNK-SGSSFITGSYDRTCKIWDTASAEELHTLEGHRNVVYAIAFNNPFGD 191
Query: 77 LIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRR 136
++ GS + ++W K TL GH A I + F+P +A+GS DT +LWD+ +
Sbjct: 190 KVITGSFDKTCKLWSTADGKCYHTLRGHTAEIVCVSFNPSSTLIATGSMDTTCRLWDVEK 11
Score = 53.1 bits (126), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 28/90 (31%), Positives = 42/90 (46%)
Frame = -1
Query: 7 TKTAWKLQEIVAHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPV 66
T +A +L + H + V ++ G + TG D LWS C +L GHT+ +
Sbjct: 274 TASAEELHTLEGHRNVVYAIAFNNPFGDKVITGSFDKTCKLWSTADGKCYHTLRGHTAEI 95
Query: 67 ESVRLNTPEELIVAGSQSGSIRVWDLEAAK 96
V N LI GS + R+WD+E A+
Sbjct: 94 VCVSFNPSSTLIATGSMDTTCRLWDVEKAQ 5
Score = 48.1 bits (113), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 26/111 (23%), Positives = 47/111 (42%), Gaps = 1/111 (0%)
Frame = -1
Query: 144 RGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFH-PNEY 202
R H + + F+ G + + D T K+WD + + + GH V + F+ P
Sbjct: 370 RAHILPLTNVAFNKSGSSFITGSYDRTCKIWDTASAEELHTLEGHRNVVYAIAFNNPFGD 191
Query: 203 LLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVLFNPDGCCLYSGCQDS 253
+ +GS D+T + W + + G + V FNP + +G D+
Sbjct: 190 KVITGSFDKTCKLWSTADGKCYHTLRGHTAEIVCVSFNPSSTLIATGSMDT 38
Score = 35.4 bits (80), Expect = 0.068, Method: Compositional matrix adjust.
Identities = 25/104 (24%), Positives = 46/104 (44%), Gaps = 2/104 (1%)
Frame = -1
Query: 167 DDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSC 226
DDH L+ + H P+ V F+ + +GS DRT + WD + +
Sbjct: 403 DDHHFYLFKV--------LRAHILPLTNVAFNKSGSSFITGSYDRTCKIWDTASAEELHT 248
Query: 227 IEGEPGPVRSVLF-NPDGCCLYSGCQD-SLRVYGWEPERCFDVV 268
+EG V ++ F NP G + +G D + +++ +C+ +
Sbjct: 247 LEGHRNVVYAIAFNNPFGDKVITGSFDKTCKLWSTADGKCYHTL 116
>29912
Length = 510
Score = 78.2 bits (191), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 58/159 (36%), Positives = 82/159 (51%), Gaps = 19/159 (11%)
Frame = +3
Query: 74 PEELIVA------------GSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVA 121
PEE I A G+ +G ++VWD+ K LRT+ GH A + SL ++ + V+
Sbjct: 6 PEEYIGAVSWIKEGNYLALGTSTGEVQVWDVTQQKKLRTMAGHAARVGSLSWNSF--IVS 179
Query: 122 SGSQDTNIKLWDIR-RKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLW--DLTA 178
SGS+ NI D+R V GHSQ V LR+SPDGK+LAS A+D+ + +W +T
Sbjct: 180 SGSRSGNIHHHDVRVADHHVGTLSGHSQEVCGLRWSPDGKYLASGANDNLLCVWPAQVTG 359
Query: 179 GKM---MSEFPGHTGPVNVVEFHPNE-YLLASGSSDRTI 213
G + F H V + + P + LASG D I
Sbjct: 360 GNSTQPLHTFSQHQAAVKALAWCPWQPSXLASGGGDVLI 476
Score = 59.3 bits (142), Expect = 4e-09, Method: Compositional matrix adjust.
Identities = 37/131 (28%), Positives = 66/131 (50%), Gaps = 6/131 (4%)
Frame = +3
Query: 33 GRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDL 92
G LA G V +W + + + ++ GH + V S+ N+ ++ +GS+SG+I D+
Sbjct: 45 GNYLALGTSTGEVQVWDVTQQKKLRTMAGHAARVGSLSWNS--FIVSSGSRSGNIHHHDV 218
Query: 93 EAA-KILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGC-----VFRYRGH 146
A + TL GH +C L + P G+++ASG+ D + +W + G + + H
Sbjct: 219 RVADHHVGTLSGHSQEVCGLRWSPDGKYLASGANDNLLCVWPAQVTGGNSTQPLHTFSQH 398
Query: 147 SQAVRCLRFSP 157
AV+ L + P
Sbjct: 399 QAAVKALAWCP 431
Score = 43.5 bits (101), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 29/111 (26%), Positives = 51/111 (45%), Gaps = 1/111 (0%)
Frame = +3
Query: 145 GHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLL 204
G + + + + +G +LA V++WD+T K + GH V + + N +++
Sbjct: 3 GPEEYIGAVSWIKEGNYLALGTSTGEVQVWDVTQQKKLRTMAGHAARVGSLSW--NSFIV 176
Query: 205 ASGSSDRTIRFWDLE-KFQVVSCIEGEPGPVRSVLFNPDGCCLYSGCQDSL 254
+SGS I D+ V + G V + ++PDG L SG D+L
Sbjct: 177 SSGSRSGNIHHHDVRVADHHVGTLSGHSQEVCGLRWSPDGKYLASGANDNL 329
>12574
Length = 521
Score = 75.1 bits (183), Expect = 8e-14, Method: Composition-based stats.
Identities = 39/109 (35%), Positives = 57/109 (52%)
Frame = +3
Query: 100 TLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDG 159
TL GH + ++ F P G+++AS S D IK+W GH + + +S D
Sbjct: 171 TLAGHTKALSAVKFSPNGDWLASSSADKLIKIWGAYDGKFEKTIAGHKLGLSDVAWSSDS 350
Query: 160 KWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGS 208
K L SA+DD T+K+W+ + GK M GH+ V F+P L+ SGS
Sbjct: 351 KLLCSASDDKTLKIWEFSTGKCMKTLKGHSNYVFCCNFNPQSNLIVSGS 497
Score = 72.0 bits (175), Expect = 7e-13, Method: Composition-based stats.
Identities = 34/109 (31%), Positives = 57/109 (52%)
Frame = +3
Query: 141 FRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPN 200
F GH++A+ ++FSP+G WLAS++ D +K+W GK GH ++ V + +
Sbjct: 168 FTLAGHTKALSAVKFSPNGDWLASSSADKLIKIWGAYDGKFEKTIAGHKLGLSDVAWSSD 347
Query: 201 EYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVLFNPDGCCLYSG 249
LL S S D+T++ W+ + + ++G V FNP + SG
Sbjct: 348 SKLLCSASDDKTLKIWEFSTGKCMKTLKGHSNYVFCCNFNPQSNLIVSG 494
Score = 60.1 bits (144), Expect = 3e-09, Method: Composition-based stats.
Identities = 27/109 (24%), Positives = 52/109 (47%)
Frame = +3
Query: 58 SLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYG 117
+L GHT + +V+ + + + + S I++W K +T+ GHK + + +
Sbjct: 171 TLAGHTKALSAVKFSPNGDWLASSSADKLIKIWGAYDGKFEKTIAGHKLGLSDVAWSSDS 350
Query: 118 EFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAA 166
+ + S S D +K+W+ C+ +GHS V C F+P + S +
Sbjct: 351 KLLCSASDDKTLKIWEFSTGKCMKTLKGHSNYVFCCNFNPQSNLIVSGS 497
Score = 49.3 bits (116), Expect = 5e-06, Method: Composition-based stats.
Identities = 26/117 (22%), Positives = 53/117 (45%)
Frame = +3
Query: 8 KTAWKLQEIVAHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVE 67
K + L+ +A + S V +G LA+ D + +W ++ GH +
Sbjct: 147 KPTYTLKFTLAGHTKALSAVKFSPNGDWLASSSADKLIKIWGAYDGKFEKTIAGHKLGLS 326
Query: 68 SVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGS 124
V ++ +L+ + S ++++W+ K ++TL GH + +F+P + SGS
Sbjct: 327 DVAWSSDSKLLCSASDDKTLKIWEFSTGKCMKTLKGHSNYVFCCNFNPQSNLIVSGS 497
Score = 38.9 bits (89), Expect = 0.006, Method: Composition-based stats.
Identities = 23/83 (27%), Positives = 40/83 (48%), Gaps = 1/83 (1%)
Frame = +3
Query: 187 GHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVLFNPDGCCL 246
GHT ++ V+F PN LAS S+D+ I+ W + I G + V ++ D L
Sbjct: 180 GHTKALSAVKFSPNGDWLASSSADKLIKIWGAYDGKFEKTIAGHKLGLSDVAWSSDSKLL 359
Query: 247 YSGCQD-SLRVYGWEPERCFDVV 268
S D +L+++ + +C +
Sbjct: 360 CSASDDKTLKIWEFSTGKCMKTL 428
>19498
Length = 903
Score = 67.4 bits (163), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 46/141 (32%), Positives = 69/141 (48%), Gaps = 22/141 (15%)
Frame = -1
Query: 146 HSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAG-----------------KMMSEFPGH 188
H V C+R+S +GK+LAS DD + +W ++ G + ++ GH
Sbjct: 789 HLGCVNCVRWSENGKFLASGGDDKLIMIWQISRGFGSGKSFGSNVTILEHWRSVATLRGH 610
Query: 189 TGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKF-QVVSCIEGEPGPVRSVLFNPDGCCLY 247
G V + + P + LAS S D TI W+ KF + V+ I G G V+ V ++P G L
Sbjct: 609 AGDVLDLAWSPQDLWLASCSVDNTIVVWNALKFSEQVAVIRGHAGMVKGVTWDPVGRYLA 430
Query: 248 SGCQD-SLRVY---GWEPERC 264
S D +LRV+ W+ E C
Sbjct: 429 SQSDDKTLRVWRTSDWKEETC 367
Score = 67.0 bits (162), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 51/177 (28%), Positives = 81/177 (45%), Gaps = 24/177 (13%)
Frame = -1
Query: 91 DLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRK------------- 137
D + ++L + H + + + G+F+ASG D I +W I R
Sbjct: 828 DDDVPRVLCQMDSHLGCVNCVRWSENGKFLASGGDDKLIMIWQISRGFGSGKSFGSNVTI 649
Query: 138 ----GCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWD-LTAGKMMSEFPGHTGPV 192
V RGH+ V L +SP WLAS + D+T+ +W+ L + ++ GH G V
Sbjct: 648 LEHWRSVATLRGHAGDVLDLAWSPQDLWLASCSVDNTIVVWNALKFSEQVAVIRGHAGMV 469
Query: 193 NVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEG---EPGPVRSVL---FNPDG 243
V + P LAS S D+T+R W ++ +C++ E G VL ++PDG
Sbjct: 468 KGVTWDPVGRYLASQSDDKTLRVWRTSDWKEETCVKSCFKECGGTTHVLRLNWSPDG 298
Score = 64.7 bits (156), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 62/250 (24%), Positives = 111/250 (44%), Gaps = 47/250 (18%)
Frame = -1
Query: 32 SGRLLATGGDDCRVNLWSINKP-----------------NCIMSLTGHTSPVESVRLNTP 74
+G+ LA+GGDD + +W I++ + +L GH V + +
Sbjct: 753 NGKFLASGGDDKLIMIWQISRGFGSGKSFGSNVTILEHWRSVATLRGHAGDVLDLAWSPQ 574
Query: 75 EELIVAGSQSGSIRVWD-LEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLW- 132
+ + + S +I VW+ L+ ++ + + GH + + + P G ++AS S D +++W
Sbjct: 573 DLWLASCSVDNTIVVWNALKFSEQVAVIRGHAGMVKGVTWDPVGRYLASQSDDKTLRVWR 394
Query: 133 --DIRRKGCV---FRYRGHSQAVRCLRFSPDGKWLASAADDH----TVKLWDLTAGKMMS 183
D + + CV F+ G + V L +SPDG + SA + T ++ +
Sbjct: 393 TSDWKEETCVKSCFKECGGTTHVLRLNWSPDGNHVVSAHAMNNAXPTAQIIERNGWGTSL 214
Query: 184 EFPGHTGPVNVVEFHP--------------NEY-LLASGSSDRTIRFW--DLEKFQVV-- 224
+F GH + VV F+P +Y A GS DR++ W L + VV
Sbjct: 213 DFVGHRKAITVVRFNPKILSKQIKKSAEKQQQYSCCAIGSKDRSLSIWLTALRRPLVVMH 34
Query: 225 SCIEGEPGPV 234
+C++ PG V
Sbjct: 33 ACLKVHPGCV 4
>02960
Length = 1577
Score = 65.5 bits (158), Expect = 7e-11, Method: Compositional matrix adjust.
Identities = 64/242 (26%), Positives = 103/242 (42%), Gaps = 38/242 (15%)
Frame = +2
Query: 38 TGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEE-----LIVAGSQSGSIRVWDL 92
+G D V LWS K IM++ GHTSPV+ V +E V GS + VW
Sbjct: 530 SGSYDNTVRLWS-TKGEAIMTIPGHTSPVKCVAWIKHDESSGVSTFVTGSHDQTALVWQW 706
Query: 93 E----AAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLW------------DIRR 136
+ + GH A++ + P + + +GS D +KLW D R
Sbjct: 707 QRETNEVDCRLSCRGHAASVDCVAVSPDSQQMCTGSWDKMLKLWSTDCNVDGDQSEDTER 886
Query: 137 KGC--------------VFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMM 182
V GH++AV +R+ D + +++ DH+++LWDL +
Sbjct: 887 PSKKKKSAKSTTQTRVPVLTLSGHAEAVSAVRW-LDPHRVVTSSWDHSLRLWDLHTAQQT 1063
Query: 183 SEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWD--LEKFQVVSC-IEGEPGPVRSVLF 239
S G ++V + P ++L +GS+DR +R D + + V C G V V +
Sbjct: 1064SLIQGSKAVLDVA-YSPLSHMLITGSADRHVRLVDPRCSEGETVKCAFTSHTGWVTGVDW 1240
Query: 240 NP 241
+P
Sbjct: 1241SP 1246
Score = 57.0 bits (136), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 52/210 (24%), Positives = 89/210 (42%), Gaps = 36/210 (17%)
Frame = +2
Query: 79 VAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGE------FVASGSQDTNIKLW 132
++GS ++R+W + I+ T+ GH + + + + + E FV +GS D +W
Sbjct: 527 LSGSYDNTVRLWSTKGEAIM-TIPGHTSPVKCVAWIKHDESSGVSTFV-TGSHDQTALVW 700
Query: 133 DIRRK----GCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLW--DLTAGKMMSE-- 184
+R+ C RGH+ +V C+ SPD + + + + D +KLW D SE
Sbjct: 701 QWQRETNEVDCRLSCRGHAASVDCVAVSPDSQQMCTGSWDKMLKLWSTDCNVDGDQSEDT 880
Query: 185 ----------------------FPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQ 222
GH V+ V + + + + + S D ++R WDL Q
Sbjct: 881 ERPSKKKKSAKSTTQTRVPVLTLSGHAEAVSAVRW-LDPHRVVTSSWDHSLRLWDLHTAQ 1057
Query: 223 VVSCIEGEPGPVRSVLFNPDGCCLYSGCQD 252
S I+G V V ++P L +G D
Sbjct: 1058QTSLIQGSKA-VLDVAYSPLSHMLITGSAD 1144
Score = 50.8 bits (120), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 56/219 (25%), Positives = 92/219 (42%), Gaps = 37/219 (16%)
Frame = +2
Query: 36 LATGGDDCRVNLW----SINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVW- 90
TG D +W N+ +C +S GH + V+ V ++ + + GS +++W
Sbjct: 662 FVTGSHDQTALVWQWQRETNEVDCRLSCRGHAASVDCVAVSPDSQQMCTGSWDKMLKLWS 841
Query: 91 -----------DLEAAKI--------------LRTLMGHKANICS---LDFHPYGEFVAS 122
D E + TL GH + + LD H V +
Sbjct: 842 TDCNVDGDQSEDTERPSKKKKSAKSTTQTRVPVLTLSGHAEAVSAVRWLDPHR----VVT 1009
Query: 123 GSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWD--LTAGK 180
S D +++LWD+ +G S+AV + +SP L + + D V+L D + G+
Sbjct: 1010SSWDHSLRLWDLHTAQQTSLIQG-SKAVLDVAYSPLSHMLITGSADRHVRLVDPRCSEGE 1186
Query: 181 MMS-EFPGHTGPVNVVEFHPN-EYLLASGSSDRTIRFWD 217
+ F HTG V V++ P E+L SGS D ++ WD
Sbjct: 1187TVKCAFTSHTGWVTGVDWSPTREHLFLSGSYDNVLKLWD 1303
Score = 39.7 bits (91), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 29/100 (29%), Positives = 45/100 (45%), Gaps = 9/100 (9%)
Frame = +2
Query: 164 SAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNE-----YLLASGSSDRTIRFWDL 218
S + D+TV+LW T G+ + PGHT PV V + ++ +GS D+T W
Sbjct: 530 SGSYDNTVRLWS-TKGEAIMTIPGHTSPVKCVAWIKHDESSGVSTFVTGSHDQTALVWQW 706
Query: 219 EK-FQVVSC---IEGEPGPVRSVLFNPDGCCLYSGCQDSL 254
++ V C G V V +PD + +G D +
Sbjct: 707 QRETNEVDCRLSCRGHAASVDCVAVSPDSQQMCTGSWDKM 826
Score = 35.8 bits (81), Expect = 0.056, Method: Compositional matrix adjust.
Identities = 35/147 (23%), Positives = 54/147 (36%), Gaps = 46/147 (31%)
Frame = +2
Query: 56 IMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANI------- 108
+++L+GH V +VR P +V S S+R+WDL A+ + G KA +
Sbjct: 938 VLTLSGHAEAVSAVRWLDPHR-VVTSSWDHSLRLWDLHTAQQTSLIQGSKAVLDVAYSPL 1114
Query: 109 -------------------CS------------------LDFHPYGE-FVASGSQDTNIK 130
CS +D+ P E SGS D +K
Sbjct: 1115 SHMLITGSADRHVRLVDPRCSEGETVKCAFTSHTGWVTGVDWSPTREHLFLSGSYDNVLK 1294
Query: 131 LWDIRR-KGCVFRYRGHSQAVRCLRFS 156
LWD R K ++ H + + +S
Sbjct: 1295 LWDTRSPKATLYDMNWHEDRILAVDWS 1375
>01805
Length = 2124
Score = 64.7 bits (156), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 55/183 (30%), Positives = 76/183 (41%), Gaps = 26/183 (14%)
Frame = -1
Query: 111 LDFHPY----GEFVASGSQDTNIKLWDIRRKGCVF--------------------RYRGH 146
L+F Y G FVA GS + I++WD+ V GH
Sbjct: 756 LNFDGYDNAPGNFVAIGSMEPVIEIWDLDIMESVGPTLTLGSKPKKTKKKMKQKESVTGH 577
Query: 147 SQAVRCLRFSPDGKW-LASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPN-EYLL 204
+QAV L ++ + + LASA+ D TV LWDL+ GKM F H+ V +HP E L
Sbjct: 576 TQAVLDLSWNRNARHVLASASADTTVALWDLSEGKMAMNFTQHSREVQCCNWHPQEEQTL 397
Query: 205 ASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVLFNPDGCCLYSGCQDSLRVYGWEPERC 264
+GS D T++ D + G V ++N C D VY C
Sbjct: 396 LTGSFDNTVKVVDCRSAETCHKSWTVEGEVEKAVWNHHNPLQLLACTDKGMVY------C 235
Query: 265 FDV 267
FD+
Sbjct: 234 FDI 226
Score = 43.5 bits (101), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 37/166 (22%), Positives = 71/166 (42%), Gaps = 4/166 (2%)
Frame = -1
Query: 58 SLTGHTSPVESVRLN-TPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPY 116
S+TGHT V + N ++ + S ++ +WDL K+ H + ++HP
Sbjct: 591 SVTGHTQAVLDLSWNRNARHVLASASADTTVALWDLSEGKMAMNFTQHSREVQCCNWHPQ 412
Query: 117 GE-FVASGSQDTNIKLWDIRR-KGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLW 174
E + +GS D +K+ D R + C + + + + + L + D V +
Sbjct: 411 EEQTLLTGSFDNTVKVVDCRSAETCHKSWTVEGEVEKAVWNHHNPLQLLACTDKGMVYCF 232
Query: 175 DLTAGKMMSEFPGHTGPVNVVEFHPN-EYLLASGSSDRTIRFWDLE 219
D+ K + H+ V V L+ + S D+T++ WD++
Sbjct: 231 DIRHEKPVFSVGAHSSCVTGVCLSSQIPGLMITTSEDKTMKVWDIQ 94
>03395
Length = 2795
Score = 64.7 bits (156), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 42/206 (20%), Positives = 85/206 (41%), Gaps = 9/206 (4%)
Frame = +2
Query: 31 ASGRLLATGGDDCRVNLWSI--------NKPNCIMSLTGHTSPVESVRLNTPEELIVAGS 82
+ G L +GG + +V +W I + + + ++ H V +++++T + V+ S
Sbjct: 26 SCGTKLVSGGGEGQVRVWDIVKDMLTGKTRGDLVANMKEHKGKVTAIQIHTNDRCCVSAS 205
Query: 83 QSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFR 142
GS +WDL + ++ + C F + + D I W++ G +
Sbjct: 206 TDGSTIIWDLITNTRSQIVLANTLFKCVC-FGGKDLHILTSGTDHKIGYWEVGDGGLLRE 382
Query: 143 YRG-HSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNE 201
G + A+ + DG+ + + +D +KLW G++ GH+ + PN
Sbjct: 383 LEGSQTGAINTIDIDRDGQTILTGGEDSLLKLWRYNEGEVTHTGIGHSNQITKARICPNR 562
Query: 202 YLLASGSSDRTIRFWDLEKFQVVSCI 227
+ + SG D + W V C+
Sbjct: 563 HYIVSGGEDGALHIWKFPDGC*VDCL 640
>12960
Length = 550
Score = 64.3 bits (155), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 33/105 (31%), Positives = 54/105 (51%)
Frame = +2
Query: 113 FHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVK 172
F + + D ++KLW+ R+ + Y GH V + S D + S D TV
Sbjct: 197 FSVDSRYCMTCGSDKSVKLWNPHRELFLKTYIGHGHEVLDAQGSGDNSQICSGGIDKTVV 376
Query: 173 LWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWD 217
L+D+ +G+ + ++ H G VN V+F+ ++ SGS D T+R WD
Sbjct: 377 LFDVASGQALRKYRDHAGTVNCVKFNEESTVILSGSLDNTVRAWD 511
Score = 56.2 bits (134), Expect = 4e-08, Method: Compositional matrix adjust.
Identities = 38/136 (27%), Positives = 61/136 (44%)
Frame = +2
Query: 125 QDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSE 184
Q+TN+K RK + QAVR +RFS D ++ + D +VKLW+ +
Sbjct: 113 QNTNMKFELPDRKEVTINCK--QQAVRAVRFSVDSRYCMTCGSDKSVKLWNPHRELFLKT 286
Query: 185 FPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVLFNPDGC 244
+ GH V + + + SG D+T+ +D+ Q + G V V FN +
Sbjct: 287 YIGHGHEVLDAQGSGDNSQICSGGIDKTVVLFDVASGQALRKYRDHAGTVNCVKFNEEST 466
Query: 245 CLYSGCQDSLRVYGWE 260
+ SG D+ V W+
Sbjct: 467 VILSGSLDNT-VRAWD 511
Score = 53.5 bits (127), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 29/113 (25%), Positives = 55/113 (48%), Gaps = 2/113 (1%)
Frame = +2
Query: 65 PVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEF--VAS 122
V +VR + + S+++W+ L+T +GH + LD G+ + S
Sbjct: 179 AVRAVRFSVDSRYCMTCGSDKSVKLWNPHRELFLKTYIGHGHEV--LDAQGSGDNSQICS 352
Query: 123 GSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWD 175
G D + L+D+ + +YR H+ V C++F+ + + S + D+TV+ WD
Sbjct: 353 GGIDKTVVLFDVASGQALRKYRDHAGTVNCVKFNEESTVILSGSLDNTVRAWD 511
Score = 45.4 bits (106), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 24/104 (23%), Positives = 46/104 (44%)
Frame = +2
Query: 34 RLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLE 93
R T G D V LW+ ++ + + GH V + + I +G ++ ++D+
Sbjct: 212 RYCMTCGSDKSVKLWNPHRELFLKTYIGHGHEVLDAQGSGDNSQICSGGIDKTVVLFDVA 391
Query: 94 AAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRK 137
+ + LR H + + F+ + SGS D ++ WD R +
Sbjct: 392 SGQALRKYRDHAGTVNCVKFNEESTVILSGSLDNTVRAWDTRSR 523
>13278
Length = 870
Score = 64.3 bits (155), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 34/101 (33%), Positives = 56/101 (55%)
Frame = +1
Query: 120 VASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAG 179
+AS S D+ ++LW++ R C+ H + V + FSPDGK+LAS + D V +W++ G
Sbjct: 121 LASASFDSTVRLWEVERGLCLHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNVQTG 300
Query: 180 KMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEK 220
++ + G G V H + + AS +SD ++ DL K
Sbjct: 301 SLVHSYKGTGGIFEVCWNHRGDKVGAS-ASDGSVFVLDLRK 420
Score = 58.9 bits (141), Expect = 5e-09, Method: Compositional matrix adjust.
Identities = 38/139 (27%), Positives = 73/139 (52%), Gaps = 9/139 (6%)
Frame = +1
Query: 47 LWSINKPNCIMSLTGHTSPVESVRL--------NTPEELIVA-GSQSGSIRVWDLEAAKI 97
+WS+ K +CI L T + +++ N LI+A S ++R+W++E
Sbjct: 1 IWSMGKDSCIHDLQLTTKEIYTIKWSPTGPGTSNPNTSLILASASFDSTVRLWEVERGLC 180
Query: 98 LRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSP 157
L TL H+ + S+ F P G+++ASGS D + +W+++ V Y+G + + + ++
Sbjct: 181 LHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNVQTGSLVHSYKG-TGGIFEVCWNH 357
Query: 158 DGKWLASAADDHTVKLWDL 176
G + ++A D +V + DL
Sbjct: 358 RGDKVGASASDGSVFVLDL 414
Score = 57.8 bits (138), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 34/122 (27%), Positives = 60/122 (49%), Gaps = 9/122 (7%)
Frame = +1
Query: 131 LWDIRRKGCVFRYRGHSQAVRCLRFSPDGKW---------LASAADDHTVKLWDLTAGKM 181
+W + + C+ + ++ + +++SP G LASA+ D TV+LW++ G
Sbjct: 1 IWSMGKDSCIHDLQLTTKEIYTIKWSPTGPGTSNPNTSLILASASFDSTVRLWEVERGLC 180
Query: 182 MSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVLFNP 241
+ H PV V F P+ LASGS D+ + W+++ +V +G G + V +N
Sbjct: 181 LHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNVQTGSLVHSYKGT-GGIFEVCWNH 357
Query: 242 DG 243
G
Sbjct: 358 RG 363
Score = 43.1 bits (100), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 37/109 (33%), Positives = 54/109 (49%), Gaps = 2/109 (1%)
Frame = +1
Query: 198 HPNEYL-LASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVLFNPDGCCLYSGCQDSLRV 256
+PN L LAS S D T+R W++E+ + + PV SV F+PDG L SG D V
Sbjct: 100 NPNTSLILASASFDSTVRLWEVERGLCLHTLTKHQEPVYSVAFSPDGKYLASGSFDKC-V 276
Query: 257 YGWEPERCFDVVLVNWGKVADLAIC-NDQLIGVAFSQSNVSSYVVDLTR 304
+ W + +V G +C N + V S S+ S +V+DL +
Sbjct: 277 HIWNVQTG-SLVHSYKGTGGIFEVCWNHRGDKVGASASDGSVFVLDLRK 420
>16199
Length = 694
Score = 53.5 bits (127), Expect(2) = 1e-10, Method: Compositional matrix adjust.
Identities = 32/104 (30%), Positives = 53/104 (50%), Gaps = 1/104 (0%)
Frame = +1
Query: 117 GEFVASGSQDTNIKLWDIRR-KGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWD 175
G ++A+ ++D+ +KLWD+R+ K G V+ L F G +LA A D V+++
Sbjct: 232 GYYLATSAEDSVVKLWDLRKLKNFKTLQLGDKYEVKALCFDQSGTYLAVAGSD--VRVYL 405
Query: 176 LTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLE 219
++ F HT V F N +AS S DR+++F+ L
Sbjct: 406 CKQWNELAVFNDHTATATGVRFGTNANFIASASMDRSLKFFGLN 537
Score = 30.4 bits (67), Expect(2) = 1e-10, Method: Compositional matrix adjust.
Identities = 13/41 (31%), Positives = 23/41 (56%), Gaps = 1/41 (2%)
Frame = +2
Query: 74 PEELIVA-GSQSGSIRVWDLEAAKILRTLMGHKANICSLDF 113
P+ LI A G++ I++WDL+ + GH+ + S+ F
Sbjct: 101 PDGLIFATGTEDSVIKIWDLKERANVANFQGHQGPVTSISF 223
Score = 44.7 bits (104), Expect(2) = 7e-09, Method: Compositional matrix adjust.
Identities = 19/50 (38%), Positives = 30/50 (60%), Gaps = 1/50 (2%)
Frame = +2
Query: 113 FHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSP-DGKW 161
FHP G A+G++D+ IK+WD++ + V ++GH V + FS D W
Sbjct: 95 FHPDGLIFATGTEDSVIKIWDLKERANVANFQGHQGPVTSISFSETDTTW 244
Score = 33.5 bits (75), Expect(2) = 7e-09, Method: Compositional matrix adjust.
Identities = 26/102 (25%), Positives = 38/102 (37%), Gaps = 41/102 (40%)
Frame = +1
Query: 158 DGKWLASAADDHTVKLWDL------------------------------TAG-------- 179
+G +LA++A+D VKLWDL AG
Sbjct: 229 NGYYLATSAEDSVVKLWDLRKLKNFKTLQLGDKYEVKALCFDQSGTYLAVAGSDVRVYLC 408
Query: 180 ---KMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDL 218
++ F HT V F N +AS S DR+++F+ L
Sbjct: 409 KQWNELAVFNDHTATATGVRFGTNANFIASASMDRSLKFFGL 534
Score = 48.5 bits (114), Expect = 9e-06, Method: Compositional matrix adjust.
Identities = 19/49 (38%), Positives = 28/49 (57%)
Frame = +2
Query: 149 AVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEF 197
A+ C +F PDG A+ +D +K+WDL ++ F GH GPV + F
Sbjct: 77 ALTCAQFHPDGLIFATGTEDSVIKIWDLKERANVANFQGHQGPVTSISF 223
Score = 45.1 bits (105), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 23/78 (29%), Positives = 39/78 (50%), Gaps = 12/78 (15%)
Frame = +2
Query: 195 VEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVLFNPDGC-------CLY 247
+FHP+ + A+G+ D I+ WDL++ V+ +G GPV S+ F+ L+
Sbjct: 89 AQFHPDGLIFATGTEDSVIKIWDLKERANVANFQGHQGPVTSISFSETDTTWPRQQKTLW 268
Query: 248 SGCQD-----SLRVYGWE 260
S C + ++Y WE
Sbjct: 269 SNCGT*GN*RTSKLYSWE 322
Score = 36.6 bits (83), Expect = 0.036, Method: Compositional matrix adjust.
Identities = 29/105 (27%), Positives = 47/105 (44%), Gaps = 2/105 (1%)
Frame = +1
Query: 32 SGRLLATGGDDCRVNLWSINKPNCIMSLT-GHTSPVESVRLN-TPEELIVAGSQSGSIRV 89
+G LAT +D V LW + K +L G V+++ + + L VAGS +RV
Sbjct: 229 NGYYLATSAEDSVVKLWDLRKLKNFKTLQLGDKYEVKALCFDQSGTYLAVAGSD---VRV 399
Query: 90 WDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDI 134
+ + L H A + F F+AS S D ++K + +
Sbjct: 400 YLCKQWNELAVFNDHTATATGVRFGTNANFIASASMDRSLKFFGL 534
Score = 34.7 bits (78), Expect = 0.13, Method: Compositional matrix adjust.
Identities = 21/76 (27%), Positives = 37/76 (48%), Gaps = 1/76 (1%)
Frame = +1
Query: 183 SEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIE-GEPGPVRSVLFNP 241
+ PG G ++ N Y LA+ + D ++ WDL K + ++ G+ V+++ F+
Sbjct: 178 GQLPGPPGTRHLHLLL*NGYYLATSAEDSVVKLWDLRKLKNFKTLQLGDKYEVKALCFDQ 357
Query: 242 DGCCLYSGCQDSLRVY 257
G L D +RVY
Sbjct: 358 SGTYLAVAGSD-VRVY 402
Score = 31.6 bits (70), Expect = 0.94, Method: Compositional matrix adjust.
Identities = 11/40 (27%), Positives = 21/40 (52%)
Frame = +2
Query: 33 GRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLN 72
G + ATG +D + +W + + + + GH PV S+ +
Sbjct: 107 GLIFATGTEDSVIKIWDLKERANVANFQGHQGPVTSISFS 226
>03387
Length = 1891
Score = 63.5 bits (153), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 52/199 (26%), Positives = 86/199 (43%), Gaps = 15/199 (7%)
Frame = +1
Query: 78 IVAGSQSGSIRVWDLEAAK-------ILRTLMGHKANICSLDFHPYGE-FVASGSQDTNI 129
+++ S +I +WD+ + + GH + + + +H E S + D +
Sbjct: 409 LLSASDDHTICLWDINSTQRESRVVDAHTIFTGHTSVVEDVAWHLLHESLFGSVADDQKL 588
Query: 130 KLWDIRRKGCV---FRYRGHSQAVRCLRFSPDGKW-LASAADDHTVKLWDLTAGKM-MSE 184
+WD R H+ V CL F+P ++ LA+ + D TV LWDL K+ +
Sbjct: 589 MIWDTRSNTTSKPSHVVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHS 768
Query: 185 FPGHTGPVNVVEFHP-NEYLLASGSSDRTIRFWDLEKFQVVSCIE-GEPGPVRSVLFNPD 242
F H + V++ P NE +LAS +DR + WDL K E E GP P+
Sbjct: 769 FESHKDEIFQVQWSPHNETILASSGTDRRLHVWDLSKIGEEQLPEDAEDGP-------PE 927
Query: 243 GCCLYSGCQDSLRVYGWEP 261
++ G + + W P
Sbjct: 928 LLFIHGGHTAKISDFSWNP 984
Score = 59.3 bits (142), Expect = 5e-09, Method: Compositional matrix adjust.
Identities = 48/174 (27%), Positives = 81/174 (46%), Gaps = 14/174 (8%)
Frame = +1
Query: 101 LMGHKANICSLDFHP-YGEFVASGSQDTNIKLWDI---RRKGCVFR----YRGHSQAVRC 152
L GH+ L ++P + S S D I LWDI +R+ V + GH+ V
Sbjct: 349 LKGHQKEGYGLSWNPNLNGHLLSASDDHTICLWDINSTQRESRVVDAHTIFTGHTSVVED 528
Query: 153 LRFSPDGKWL-ASAADDHTVKLWDL---TAGKMMSEFPGHTGPVNVVEFHP-NEYLLASG 207
+ + + L S ADD + +WD T K HT VN + F+P +E++LA+G
Sbjct: 529 VAWHLLHESLFGSVADDQKLMIWDTRSNTTSKPSHVVDAHTAEVNCLSFNPYSEFILATG 708
Query: 208 SSDRTIRFWDLEKFQV-VSCIEGEPGPVRSVLFNPDGCCLYSGCQDSLRVYGWE 260
S+D+T+ WDL ++ + E + V ++P + + R++ W+
Sbjct: 709 SADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLHVWD 870
Score = 38.1 bits (87), Expect = 0.010, Method: Compositional matrix adjust.
Identities = 36/136 (26%), Positives = 58/136 (42%), Gaps = 17/136 (12%)
Frame = +1
Query: 16 IVAHASNVSSLVLGKASGRLLATGGDDCRVNLWSI-NKPNCIMSLTGHTSPVESVRLNTP 74
+ AH + V+ L S +LATG D V LW + N + S H + V+ +
Sbjct: 637 VDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPH 816
Query: 75 EELIVAGSQSG-SIRVWDLEA--------------AKILRTLMGHKANICSLDFHPYGEF 119
E I+A S + + VWDL ++L GH A I ++P +
Sbjct: 817 NETILASSGTDRRLHVWDLSKIGEEQLPEDAEDGPPELLFIHGGHTAKISDFSWNPNEPW 996
Query: 120 -VASGSQDTNIKLWDI 134
V S S+D +++W +
Sbjct: 997 IVCSVSEDNIMQVWQM 1044
>04088
Length = 511
Score = 63.2 bits (152), Expect = 3e-10, Method: Compositional matrix adjust.
Identities = 36/119 (30%), Positives = 65/119 (54%), Gaps = 3/119 (2%)
Frame = +3
Query: 148 QAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVE--FHPNEYLLA 205
+AV + F+ DG+ ++ D+TV+L D G+M++EF GH ++ + + L+
Sbjct: 33 KAVTSVTFTRDGQCSLVSSQDNTVRLMDKDTGEMLNEFTGHKHSQYKIDSCLNNEDTLVV 212
Query: 206 SGSSDRTIRFWDLEKFQVVSCIEGEPG-PVRSVLFNPDGCCLYSGCQDSLRVYGWEPER 263
SGS D + FWDL + ++V ++ + PV S+ F+ CL + C D +V+ W +
Sbjct: 213 SGSEDGKVYFWDLVEAKLVDTLDHKTTRPVHSLSFHHAELCLMTACAD--KVFLWRSSQ 383
Score = 36.6 bits (83), Expect = 0.036, Method: Compositional matrix adjust.
Identities = 19/72 (26%), Positives = 33/72 (45%), Gaps = 2/72 (2%)
Frame = +3
Query: 65 PVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLD--FHPYGEFVAS 122
V SV + + SQ ++R+ D + ++L GHK + +D + V S
Sbjct: 36 AVTSVTFTRDGQCSLVSSQDNTVRLMDKDTGEMLNEFTGHKHSQYKIDSCLNNEDTLVVS 215
Query: 123 GSQDTNIKLWDI 134
GS+D + WD+
Sbjct: 216 GSEDGKVYFWDL 251
>17266
Length = 480
Score = 62.8 bits (151), Expect = 5e-10, Method: Composition-based stats.
Identities = 39/147 (26%), Positives = 63/147 (42%), Gaps = 3/147 (2%)
Frame = -1
Query: 111 LDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHT 170
L P SG+ D + KLWD+R C + GH + + + P+G A+ +DD T
Sbjct: 441 LSLAPDMRTFVSGACDASAKLWDVRDGMCKQTFSGHESDINAITYFPNGHAFATGSDDAT 262
Query: 171 VKLWDLTAGKMMSEFPGHTG---PVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCI 227
+L+D+ A + + + H + V F + LL G D WD+ K + +
Sbjct: 261 CRLFDIRADQEIGMY-SHDNIICGITSVAFSKSGRLLLGGYDDFNCNIWDVLKQERTGVL 85
Query: 228 EGEPGPVRSVLFNPDGCCLYSGCQDSL 254
G V + DG + +G DS
Sbjct: 84 AGHDNRVSCLGVTEDGSAVATGSWDSF 4
Score = 62.0 bits (149), Expect = 7e-10, Method: Composition-based stats.
Identities = 36/135 (26%), Positives = 63/135 (46%), Gaps = 3/135 (2%)
Frame = -1
Query: 79 VAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKG 138
V+G+ S ++WD+ +T GH+++I ++ + P G A+GS D +L+DIR
Sbjct: 411 VSGACDASAKLWDVRDGMCKQTFSGHESDINAITYFPNGHAFATGSDDATCRLFDIRADQ 232
Query: 139 CVFRYRGHSQ---AVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVV 195
+ Y H + + FS G+ L DD +WD+ + GH V+ +
Sbjct: 231 EIGMY-SHDNIICGITSVAFSKSGRLLLGGYDDFNCNIWDVLKQERTGVLAGHDNRVSCL 55
Query: 196 EFHPNEYLLASGSSD 210
+ +A+GS D
Sbjct: 54 GVTEDGSAVATGSWD 10
Score = 60.5 bits (145), Expect = 2e-09, Method: Composition-based stats.
Identities = 37/115 (32%), Positives = 52/115 (45%), Gaps = 6/115 (5%)
Frame = -1
Query: 144 RGHSQAVR----CLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHP 199
R HSQA L +PD + S A D + KLWD+ G F GH +N + + P
Sbjct: 480 RRHSQATLGT**VLSLAPDMRTFVSGACDASAKLWDVRDGMCKQTFSGHESDINAITYFP 301
Query: 200 NEYLLASGSSDRTIRFWDLEKFQVVSCIEGEP--GPVRSVLFNPDGCCLYSGCQD 252
N + A+GS D T R +D+ Q + + + SV F+ G L G D
Sbjct: 300 NGHAFATGSDDATCRLFDIRADQEIGMYSHDNIICGITSVAFSKSGRLLLGGYDD 136
Score = 57.8 bits (138), Expect = 1e-08, Method: Composition-based stats.
Identities = 34/138 (24%), Positives = 58/138 (42%), Gaps = 3/138 (2%)
Frame = -1
Query: 34 RLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLE 93
R +G D LW + C + +GH S + ++ GS + R++D+
Sbjct: 420 RTFVSGACDASAKLWDVRDGMCKQTFSGHESDINAITYFPNGHAFATGSDDATCRLFDIR 241
Query: 94 AAKILRTLMGHKANIC---SLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAV 150
A + + + H IC S+ F G + G D N +WD+ ++ GH V
Sbjct: 240 ADQEI-GMYSHDNIICGITSVAFSKSGRLLLGGYDDFNCNIWDVLKQERTGVLAGHDNRV 64
Query: 151 RCLRFSPDGKWLASAADD 168
CL + DG +A+ + D
Sbjct: 63 SCLGVTEDGSAVATGSWD 10
Score = 36.6 bits (83), Expect = 0.034, Method: Composition-based stats.
Identities = 29/117 (24%), Positives = 49/117 (41%), Gaps = 3/117 (2%)
Frame = -1
Query: 14 QEIVAHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTS---PVESVR 70
Q H S+++++ +G ATG DD L+ I I + H + + SV
Sbjct: 351 QTFSGHESDINAITY-FPNGHAFATGSDDATCRLFDIRADQEI-GMYSHDNIICGITSVA 178
Query: 71 LNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDT 127
+ L++ G + +WD+ + L GH + L G VA+GS D+
Sbjct: 177 FSKSGRLLLGGYDDFNCNIWDVLKQERTGVLAGHDNRVSCLGVTEDGSAVATGSWDS 7
Score = 30.4 bits (67), Expect = 2.5, Method: Composition-based stats.
Identities = 12/60 (20%), Positives = 25/60 (41%)
Frame = -1
Query: 194 VVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVLFNPDGCCLYSGCQDS 253
V+ P+ SG+ D + + WD+ G + ++ + P+G +G D+
Sbjct: 444 VLSLAPDMRTFVSGACDASAKLWDVRDGMCKQTFSGHESDINAITYFPNGHAFATGSDDA 265
>01768
Length = 1424
Score = 59.7 bits (143), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 61/249 (24%), Positives = 110/249 (44%), Gaps = 37/249 (14%)
Frame = +3
Query: 52 KPNCIMSLTGHTSPVESVRLNTPEELIVAGSQS--GSIRVWDL----------EAA---- 95
KP + H V +R+ + I GS S GS+ V+D+ EAA
Sbjct: 480 KPELNLVTMQHNGGVNRLRVTDINDKIYTGSWSDKGSVYVYDITXQTAIVDDAEAAGKYD 659
Query: 96 ----KILRTLMGHKANICSLDFHPYGE-FVASGSQDTNIKLWDIRRKGCVFR---YRGHS 147
I+ T+ H ++D+ P + ++ +G I + G Y H+
Sbjct: 660 STQKSIVHTVTHHTTEGFAIDWSPAAKGWLVTGDCTGAIYISQPSSSGWTTEKSSYAAHT 839
Query: 148 QAVRCLRFSP-DGKWLASAADDHTVKLWDL----TAGKMMSEFPGHTGPVNVVEFHPNE- 201
+V +++SP +G AS + D T+++W+ + +++ H+ +NV+ ++P E
Sbjct: 840 DSVEDVQWSPNEGNVFASCSVDRTLRIWNTQQKPSKANVLTVPEAHSRDINVINWNPIEK 1019
Query: 202 YLLASGSSDRTIRFWDLEKFQ-----VVSCIEGEPGPVRSVLFNPDGCCLY--SGCQDSL 254
+LLASG D I+ WDL F+ + + PV S+ +NP + SG D +
Sbjct: 1020HLLASGGDDGIIKIWDLRMFRNKPVSAQASFKLHSQPVTSLEWNPQDSSVLAASGEDDQI 1199
Query: 255 RVYGWEPER 263
++ + ER
Sbjct: 1200TIWDFSVER 1226
Score = 41.2 bits (95), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 34/134 (25%), Positives = 60/134 (44%), Gaps = 22/134 (16%)
Frame = +3
Query: 18 AHASNVSSLVLGKASGRLLATGGDDCRVNLWSI----NKP-NCIMSLTGHTSPVESVRLN 72
AH+ +++ + LLA+GGDD + +W + NKP + S H+ PV S+ N
Sbjct: 972 AHSRDINVINWNPIEKHLLASGGDDGIIKIWDLRMFRNKPVSAQASFKLHSQPVTSLEWN 1151
Query: 73 TPEELIVAGS-QSGSIRVWDLEA--------------AKILRTLMGHKANICSLDFHPY- 116
+ ++A S + I +WD A++L G + +I + +HP
Sbjct: 1152 PQDSSVLAASGEDDQITIWDFSVERDEGEGEEELDVPAQLLFQHCG-QTDIKEVHWHPQL 1328
Query: 117 -GEFVASGSQDTNI 129
G +++ D NI
Sbjct: 1329 PGVLISTAKSDFNI 1370
>14555
Length = 627
Score = 40.0 bits (92), Expect(2) = 5e-09, Method: Composition-based stats.
Identities = 23/62 (37%), Positives = 34/62 (54%), Gaps = 2/62 (3%)
Frame = -2
Query: 103 GHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRC--LRFSPDGK 160
GH+A+I + F+P G+ A+GS D +L+D+R V YR S C + FS G+
Sbjct: 605 GHEADINCVRFYPSGDAFATGSDDATCRLFDLRADREVNCYRKESIIFGCNAVDFSVSGR 426
Query: 161 WL 162
L
Sbjct: 425 LL 420
Score = 38.9 bits (89), Expect(2) = 5e-09, Method: Compositional matrix adjust.
Identities = 18/55 (32%), Positives = 28/55 (50%)
Frame = -3
Query: 166 ADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEK 220
+D+TV +WD G + GH V+ + P+ L +GS D T+R W E+
Sbjct: 409 TNDYTVNVWDALKGMRSTILYGHDNRVSCLRISPDGTSLCTGSWDYTLRIWA*ER 245
Score = 43.5 bits (101), Expect(2) = 1e-07, Method: Composition-based stats.
Identities = 17/42 (40%), Positives = 25/42 (59%)
Frame = -2
Query: 139 CVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGK 180
CV + GH + C+RF P G A+ +DD T +L+DL A +
Sbjct: 623 CVQMFEGHEADINCVRFYPSGDAFATGSDDATCRLFDLRADR 498
Score = 30.4 bits (67), Expect(2) = 1e-07, Method: Compositional matrix adjust.
Identities = 18/57 (31%), Positives = 29/57 (50%), Gaps = 1/57 (1%)
Frame = -3
Query: 208 SSDRTIRFWDLEKFQVVSCIEGEPGPVRSVLFNPDGCCLYSGCQD-SLRVYGWEPER 263
++D T+ WD K + + G V + +PDG L +G D +LR++ E ER
Sbjct: 409 TNDYTVNVWDALKGMRSTILYGHDNRVSCLRISPDGTSLCTGSWDYTLRIWA*ERER 239
Score = 40.0 bits (92), Expect = 0.003, Method: Composition-based stats.
Identities = 22/60 (36%), Positives = 31/60 (51%)
Frame = -2
Query: 185 FPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVLFNPDGC 244
F GH +N V F+P+ A+GS D T R +DL + V+C E S++F GC
Sbjct: 611 FEGHEADINCVRFYPSGDAFATGSDDATCRLFDLRADREVNCYRKE-----SIIF---GC 456
Score = 38.1 bits (87), Expect = 0.012, Method: Compositional matrix adjust.
Identities = 17/51 (33%), Positives = 27/51 (52%)
Frame = -3
Query: 124 SQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLW 174
+ D + +WD + GH V CLR SPDG L + + D+T+++W
Sbjct: 409 TNDYTVNVWDALKGMRSTILYGHDNRVSCLRISPDGTSLCTGSWDYTLRIW 257
Score = 32.3 bits (72), Expect = 0.58, Method: Compositional matrix adjust.
Identities = 21/67 (31%), Positives = 33/67 (49%), Gaps = 2/67 (2%)
Frame = -3
Query: 86 SIRVWDLEAAKILRT--LMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRY 143
++ VWD A K +R+ L GH + L P G + +GS D +++W R+
Sbjct: 397 TVNVWD--ALKGMRSTILYGHDNRVSCLRISPDGTSLCTGSWDYTLRIWA*ERE------ 242
Query: 144 RGHSQAV 150
RGHS +
Sbjct: 241 RGHSSNI 221
Score = 28.5 bits (62), Expect = 9.9, Method: Compositional matrix adjust.
Identities = 19/68 (27%), Positives = 31/68 (45%)
Frame = -3
Query: 41 DDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRT 100
+D VN+W K L GH + V +R++ + GS ++R+W E +
Sbjct: 406 NDYTVNVWDALKGMRSTILYGHDNRVSCLRISPDGTSLCTGSWDYTLRIWA*ERER---- 239
Query: 101 LMGHKANI 108
GH +NI
Sbjct: 238 --GHSSNI 221
>11493
Length = 535
Score = 58.9 bits (141), Expect = 6e-09, Method: Compositional matrix adjust.
Identities = 42/167 (25%), Positives = 71/167 (42%), Gaps = 14/167 (8%)
Frame = -2
Query: 62 HTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLD--------- 112
H V +V ++ P + + G + G ++VWD+ G+K + LD
Sbjct: 480 HGEVVCAVTISNPTKYVYTGGK-GCVKVWDISQP-------GNKNPVSQLDCLQRDNYIR 325
Query: 113 ---FHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRC--LRFSPDGKWLASAAD 167
P G + G + +N+ +WD+ + S A C L SPD K S
Sbjct: 324 SVKLLPDGRTLIVGGEASNLSIWDLASPTPRIKAELTSAAPACYALAISPDSKVCFSCCS 145
Query: 168 DHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIR 214
D + +WDL ++ +F GHT + ++ P+ L +G D T+R
Sbjct: 144 DGNIAVWDLHNEILVRQFQGHTDGASCIDISPDGSRLWTGGLDNTVR 4
Score = 50.1 bits (118), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 36/163 (22%), Positives = 69/163 (42%), Gaps = 11/163 (6%)
Frame = -2
Query: 102 MGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKG---------CVFRYRGHSQAVRC 152
+ H +C++ ++V +G + +K+WDI + G C+ R +R
Sbjct: 486 LSHGEVVCAVTISNPTKYVYTGGKGC-VKVWDISQPGNKNPVSQLDCLQR----DNYIRS 322
Query: 153 LRFSPDGKWLASAADDHTVKLWDLTAG--KMMSEFPGHTGPVNVVEFHPNEYLLASGSSD 210
++ PDG+ L + + +WDL + ++ +E + P+ + S SD
Sbjct: 321 VKLLPDGRTLIVGGEASNLSIWDLASPTPRIKAELTSAAPACYALAISPDSKVCFSCCSD 142
Query: 211 RTIRFWDLEKFQVVSCIEGEPGPVRSVLFNPDGCCLYSGCQDS 253
I WDL +V +G + +PDG L++G D+
Sbjct: 141 GNIAVWDLHNEILVRQFQGHTDGASCIDISPDGSRLWTGGLDN 13
Score = 42.0 bits (97), Expect = 9e-04, Method: Compositional matrix adjust.
Identities = 23/100 (23%), Positives = 43/100 (43%), Gaps = 2/100 (2%)
Frame = -2
Query: 33 GRLLATGGDDCRVNLWSINKPN--CIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVW 90
GR L GG+ +++W + P LT ++ ++ ++ + G+I VW
Sbjct: 303 GRTLIVGGEASNLSIWDLASPTPRIKAELTSAAPACYALAISPDSKVCFSCCSDGNIAVW 124
Query: 91 DLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIK 130
DL ++R GH +D P G + +G D ++
Sbjct: 123 DLHNEILVRQFQGHTDGASCIDISPDGSRLWTGGLDNTVR 4
>02090
Length = 1841
Score = 58.9 bits (141), Expect = 6e-09, Method: Compositional matrix adjust.
Identities = 41/158 (25%), Positives = 70/158 (44%), Gaps = 12/158 (7%)
Frame = -3
Query: 39 GGDDCRVNLWSINKPN----------CIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIR 88
GG C V +W I++P C +++T + P R ++ ++
Sbjct: 1839 GGKGC-VKVWDISQPGTKAPCLNWIACNVTIT--SGPSSCCRTGAR*SW----REASTLS 1681
Query: 89 VWDLEAA--KILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGH 146
+WDL +I L +L P G+ S D NI +WD+ + V +++GH
Sbjct: 1680 IWDLATPTPRIKAELTSSAPACYALAISPDGKVCFSCCSDGNIAVWDLHNQTLVRQFQGH 1501
Query: 147 SQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSE 184
+ C+ SPDG L + D+TV+ WDL G+ + +
Sbjct: 1500 TDGASCIDISPDGTKLWTGGLDNTVRSWDLREGRQLQQ 1387
Score = 55.5 bits (132), Expect = 6e-08, Method: Compositional matrix adjust.
Identities = 37/186 (19%), Positives = 80/186 (43%)
Frame = -3
Query: 33 GRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDL 92
G++ + D + +W ++ + GHT + ++ + G ++R WDL
Sbjct: 1590 GKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISPDGTKLWTGGLDNTVRSWDL 1411
Query: 93 EAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRC 152
+ L+ + I SL + P GE++A G + +N+++ K ++ H V
Sbjct: 1410 REGRQLQQ-HDFSSQIFSLGYCPTGEWLAVGMESSNVEVLH-HSKPDKYQLHLHESCVLS 1237
Query: 153 LRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRT 212
L+F+ GKW S D+ + W G + + + V + ++ + +GS D+
Sbjct: 1236 LKFAYCGKWFVSTGKDNLLNAWRTPYGASIFQ-SKESSSVLSCDIAADDKYIVTGSGDKK 1060
Query: 213 IRFWDL 218
+++
Sbjct: 1059 ATLYEV 1042
Score = 52.4 bits (124), Expect = 5e-07, Method: Compositional matrix adjust.
Identities = 29/96 (30%), Positives = 46/96 (47%), Gaps = 2/96 (2%)
Frame = -3
Query: 127 TNIKLWDIRRKGCVFRYRGHSQAVRC--LRFSPDGKWLASAADDHTVKLWDLTAGKMMSE 184
+ + +WD+ + S A C L SPDGK S D + +WDL ++ +
Sbjct: 1692 STLSIWDLATPTPRIKAELTSSAPACYALAISPDGKVCFSCCSDGNIAVWDLHNQTLVRQ 1513
Query: 185 FPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEK 220
F GHT + ++ P+ L +G D T+R WDL +
Sbjct: 1512 FQGHTDGASCIDISPDGTKLWTGGLDNTVRSWDLRE 1405
Score = 32.0 bits (71), Expect = 0.71, Method: Compositional matrix adjust.
Identities = 31/135 (22%), Positives = 53/135 (39%), Gaps = 10/135 (7%)
Frame = -3
Query: 129 IKLWDIRRKG----CVFRYRGH----SQAVRCLRFSPDGKWLASAADDHTVKLWDLTAG- 179
+K+WDI + G C+ + S C R W ++ T+ +WDL
Sbjct: 1824 VKVWDISQPGTKAPCLNWIACNVTITSGPSSCCRTGAR*SWREAS----TLSIWDLATPT 1657
Query: 180 -KMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVL 238
++ +E + P+ + S SD I WDL +V +G +
Sbjct: 1656 PRIKAELTSSAPACYALAISPDGKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCID 1477
Query: 239 FNPDGCCLYSGCQDS 253
+PDG L++G D+
Sbjct: 1476 ISPDGTKLWTGGLDN 1432
>27270
Length = 1078
Score = 57.0 bits (136), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 40/174 (22%), Positives = 76/174 (43%), Gaps = 20/174 (11%)
Frame = +2
Query: 77 LIVAGSQSGSIRVWDLEAAKILRTL-MGHKANICSLDFHPYGEFVASGSQDTNIKLWDIR 135
++ GS GS+ ++ +E L GH + + + G + S S D ++ W++
Sbjct: 185 VVAVGSADGSVGLYSVETHTYTHMLNKGHSKAVTDMCWRADGRTLYSSSLDGHVIGWNVN 364
Query: 136 RKGCVFRYR---GHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPV 192
+ +++ G V C+ + L + DHT+K+WDLT ++ EF GH+ V
Sbjct: 365 TLHMIEKWKATSGRHHGVHCVCLCSSSRLLTA---DHTIKMWDLTTKNVLQEFSGHSTEV 535
Query: 193 --------------NVVEFHPNEYLLASGSSDRTIRFW--DLEKFQVVSCIEGE 230
++ + + Y+ ++ ++DRTI W D E Q + E
Sbjct: 536 IKLLPVLKPSSEQNDIGDSNLACYVFSAAAADRTINVWRCDSESSQATAVTSFE 697
>15118
Length = 1074
Score = 56.2 bits (134), Expect = 4e-08, Method: Compositional matrix adjust.
Identities = 40/174 (22%), Positives = 69/174 (39%), Gaps = 3/174 (1%)
Frame = +3
Query: 46 NLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDL---EAAKILRTLM 102
NL S H S V V + L++ I+ W + A++L +
Sbjct: 141 NLQSGKHRGSFGDTVAHVSGVRGVAFDAFNCLLITAGGDCDIKFWRFGSRDRARVLLKEL 320
Query: 103 GHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWL 162
I + H +A +D + + D+ V + GHS ++ L FS DG+WL
Sbjct: 321 KMSEGISRILLHRDSNMLAVVLEDFTVSVIDVDTLRVVRVFSGHSNSITDLSFSGDGRWL 500
Query: 163 ASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFW 216
+A+ D TV+ W L G+++ F ++ ++L S D + W
Sbjct: 501 ITASMDCTVRTWSLVHGRLIDCFAVEAAVTSLTMSPSQDFLATSHVGDVGVYLW 662
Score = 55.1 bits (131), Expect = 9e-08, Method: Compositional matrix adjust.
Identities = 42/211 (19%), Positives = 90/211 (42%), Gaps = 6/211 (2%)
Frame = +3
Query: 64 SPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTL---MGHKANICSLDFHPYGEFV 120
+ ++V +++ + G SG + +++L++ K + + H + + + F + +
Sbjct: 60 TTAQAVDISSCGNYVAVGYSSGHLDIYNLQSGKHRGSFGDTVAHVSGVRGVAFDAFNCLL 239
Query: 121 ASGSQDTNIKLWDI---RRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLT 177
+ D +IK W R + + S+ + + D LA +D TV + D+
Sbjct: 240 ITAGGDCDIKFWRFGSRDRARVLLKELKMSEGISRILLHRDSNMLAVVLEDFTVSVIDVD 419
Query: 178 AGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSV 237
+++ F GH+ + + F + L + S D T+R W L +++ C E V S+
Sbjct: 420 TLRVVRVFSGHSNSITDLSFSGDGRWLITASMDCTVRTWSLVHGRLIDCFAVEA-AVTSL 596
Query: 238 LFNPDGCCLYSGCQDSLRVYGWEPERCFDVV 268
+P L + + VY W + + V
Sbjct: 597 TMSPSQDFLATSHVGDVGVYLWANQTLYXFV 689
Score = 49.3 bits (116), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 40/166 (24%), Positives = 70/166 (42%), Gaps = 4/166 (2%)
Frame = +3
Query: 13 LQEIVAHASNVSSLVLGKASGRLLATGGDDCRVNLW---SINKPNCIMSLTGHTSPVESV 69
+ VAH S V + A LL T G DC + W S ++ ++ + + +
Sbjct: 171 FGDTVAHVSGVRGVAF-DAFNCLLITAGGDCDIKFWRFGSRDRARVLLKELKMSEGISRI 347
Query: 70 RLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNI 129
L+ ++ + ++ V D++ +++R GH +I L F G ++ + S D +
Sbjct: 348 LLHRDSNMLAVVLEDFTVSVIDVDTLRVVRVFSGHSNSITDLSFSGDGRWLITASMDCTV 527
Query: 130 KLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLA-SAADDHTVKLW 174
+ W + G + AV L SP +LA S D V LW
Sbjct: 528 RTWSLVH-GRLIDCFAVEAAVTSLTMSPSQDFLATSHVGDVGVYLW 662
>01462
Length = 995
Score = 55.5 bits (132), Expect = 6e-08, Method: Compositional matrix adjust.
Identities = 46/177 (25%), Positives = 76/177 (42%), Gaps = 11/177 (6%)
Frame = +2
Query: 78 IVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRK 137
+ AG+ I VWD+EA + L + GHK I + + S S+D +++WDIR
Sbjct: 242 LYAGAGDRKIHVWDIEAGQYLNAMEGHKDYIHKVVMKNDAQECVSASEDGTVRMWDIRSS 421
Query: 138 G----CVFRYRGH-------SQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFP 186
C+ + + +RCL P+ WL + W L + F
Sbjct: 422 TETVHCLEPSKNELCSRPLLGKWLRCLALDPEEGWLVCGGGP-KLSAWHLRTLAPTTIFD 598
Query: 187 GHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVLFNPDG 243
+ NV FH +E++L++G+S + W L+ + S I P V S+ N +
Sbjct: 599 TPSVSQNVALFH-DEFILSAGTSP-VMNHWRLDG-TLHSSIPCTPSSVFSLAINTNA 760
>18981
Length = 407
Score = 55.5 bits (132), Expect = 7e-08, Method: Composition-based stats.
Identities = 33/130 (25%), Positives = 66/130 (50%), Gaps = 1/130 (0%)
Frame = -2
Query: 114 HPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKL 173
H + S + D +++W ++ + RGH+ V C+ G+ + S + D T+ +
Sbjct: 397 HLLDNMIISAATDRTLRVWCLKNTCLLHTLRGHNDDVECVCIY--GRRVVSGSWDKTLIV 224
Query: 174 WDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQ-VVSCIEGEPG 232
W++ G+ + + GHT + V+F +E SGS+D +R W L+ Q +++ G+
Sbjct: 223 WEVDTGRPVHQLHGHTEAITAVQF--DEGKAVSGSADGDVRTWALDTGQCLLTMTTGQDI 50
Query: 233 PVRSVLFNPD 242
V V++N +
Sbjct: 49 EVYCVVYNQE 20
Score = 54.7 bits (130), Expect = 1e-07, Method: Composition-based stats.
Identities = 31/108 (28%), Positives = 60/108 (55%)
Frame = -2
Query: 75 EELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDI 134
+ +I++ + ++RVW L+ +L TL GH ++ + YG V SGS D + +W++
Sbjct: 388 DNMIISAATDRTLRVWCLKNTCLLHTLRGHNDDVECVCI--YGRRVVSGSWDKTLIVWEV 215
Query: 135 RRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMM 182
V + GH++A+ ++F +GK ++ +AD V+ W L G+ +
Sbjct: 214 DTGRPVHQLHGHTEAITAVQFD-EGKAVSGSADG-DVRTWALDTGQCL 77
Score = 39.7 bits (91), Expect = 0.004, Method: Composition-based stats.
Identities = 20/69 (28%), Positives = 36/69 (52%)
Frame = -2
Query: 33 GRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDL 92
GR + +G D + +W ++ + L GHT + +V+ + E V+GS G +R W L
Sbjct: 268 GRRVVSGSWDKTLIVWEVDTGRPVHQLHGHTEAITAVQFD--EGKAVSGSADGDVRTWAL 95
Query: 93 EAAKILRTL 101
+ + L T+
Sbjct: 94 DTGQCLLTM 68
>15780
Length = 735
Score = 54.7 bits (130), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 24/61 (39%), Positives = 37/61 (60%)
Frame = -1
Query: 160 KWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLE 219
K+L++A DHTV +WD+ +G ++ HT V + F + +LASG D +IR WDL
Sbjct: 735 KYLSTAGADHTVIVWDIASGTAVAHLTAHTDTVYALCFSRDGTVLASGGMDNSIRLWDLA 556
Query: 220 K 220
+
Sbjct: 555 R 553
Score = 46.2 bits (108), Expect = 4e-05, Method: Compositional matrix adjust.
Identities = 22/67 (32%), Positives = 36/67 (53%)
Frame = -1
Query: 118 EFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLT 177
+++++ D + +WDI V H+ V L FS DG LAS D++++LWDL
Sbjct: 735 KYLSTAGADHTVIVWDIASGTAVAHLTAHTDTVYALCFSRDGTVLASGGMDNSIRLWDL- 559
Query: 178 AGKMMSE 184
++M E
Sbjct: 558 -ARVMEE 541
Score = 40.4 bits (93), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 19/59 (32%), Positives = 30/59 (50%)
Frame = -1
Query: 34 RLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDL 92
+ L+T G D V +W I + LT HT V ++ + ++ +G SIR+WDL
Sbjct: 735 KYLSTAGADHTVIVWDIASGTAVAHLTAHTDTVYALCFSRDGTVLASGGMDNSIRLWDL 559
Score = 40.0 bits (92), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 17/51 (33%), Positives = 28/51 (54%)
Frame = -1
Query: 86 SIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRR 136
++ VWD+ + + L H + +L F G +ASG D +I+LWD+ R
Sbjct: 705 TVIVWDIASGTAVAHLTAHTDTVYALCFSRDGTVLASGGMDNSIRLWDLAR 553
>01249
Length = 1743
Score = 54.7 bits (130), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 38/155 (24%), Positives = 74/155 (47%), Gaps = 17/155 (10%)
Frame = -1
Query: 58 SLTGHTSPVESVRLN--TPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHP 115
++ H+ P+ + + P + + S G+ ++WD+ + +LRT++ ++ + L
Sbjct: 1227 TINAHSEPITGLHVGCGGPAARVASSSSDGTCKLWDMLSGALLRTMV-YETGVGCLIMDK 1051
Query: 116 YGEFVASGSQDTNI---KLWDIRRKGCVFRYR-----------GHSQAVRCLRFSPDGKW 161
F+ +G + +I L+ + VF + GHS AV CL FS DG+
Sbjct: 1050 QEHFLLAGLDNGDILCSPLFGQISQSEVFVSKHTTKAGERVLQGHSDAVTCLAFSSDGQR 871
Query: 162 LASAADDHTVKLWDLTAGKMMS-EFPGHTGPVNVV 195
LAS + + V +W++ +G S + G G V ++
Sbjct: 870 LASGSQNGKVIIWNMESGDSTSLDISGAVGNVMII 766
Score = 43.9 bits (102), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 55/240 (22%), Positives = 93/240 (38%), Gaps = 27/240 (11%)
Frame = -1
Query: 68 SVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDT 127
SV + +P+ L S S I +W++ ++ L+ + F G +
Sbjct: 1479 SVLVVSPDGLFCLASISEKIYIWEMTGGSLV-GLLSDFNEATKIQFTDDGSQFVVATSSG 1303
Query: 128 NIKLWDIRR--KGCVFRYRG---------HSQAVRCLRFSPDG--KWLASAADDHTVKLW 174
++ +WD R R RG HS+ + L G +AS++ D T KLW
Sbjct: 1302 HLNIWDFARVVTTTSQRARGLKPGRTINAHSEPITGLHVGCGGPAARVASSSSDGTCKLW 1123
Query: 175 DLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTI----RFWDLEKFQVV------ 224
D+ +G ++ TG V + E+ L +G + I F + + +V
Sbjct: 1122 DMLSGALLRTMVYETG-VGCLIMDKQEHFLLAGLDNGDILCSPLFGQISQSEVFVSKHTT 946
Query: 225 ----SCIEGEPGPVRSVLFNPDGCCLYSGCQDSLRVYGWEPERCFDVVLVNWGKVADLAI 280
++G V + F+ DG L SG Q+ +V W E L G V ++ I
Sbjct: 945 KAGERVLQGHSDAVTCLAFSSDGQRLASGSQNG-KVIIWNMESGDSTSLDISGAVGNVMI 769
>21105
Length = 650
Score = 54.3 bits (129), Expect = 2e-07, Method: Composition-based stats.
Identities = 27/102 (26%), Positives = 51/102 (50%), Gaps = 4/102 (3%)
Frame = +1
Query: 77 LIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRR 136
+ + + IR +D K++ ++ H ++ SL P G ++ SGS D +I+LW++
Sbjct: 106 ITITAHEDRHIRFFDNNTGKLIHAMVAHLDSVTSLAVDPNGLYLLSGSHDCSIRLWNLDS 285
Query: 137 KGCVFRYRGH----SQAVRCLRFSPDGKWLASAADDHTVKLW 174
K CV H +++ + F P ++ASA D K++
Sbjct: 286 KTCVQEITSHRKKFDESIHDVAFHPQKPYIASAGADALAKVF 411
Score = 45.8 bits (107), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 25/101 (24%), Positives = 46/101 (45%), Gaps = 4/101 (3%)
Frame = +1
Query: 114 HPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKL 173
HP + +D +I+ +D + H +V L P+G +L S + D +++L
Sbjct: 91 HPTMPITITAHEDRHIRFFDNNTGKLIHAMVAHLDSVTSLAVDPNGLYLLSGSHDCSIRL 270
Query: 174 WDLTAGKMMSEFPGHTG----PVNVVEFHPNEYLLASGSSD 210
W+L + + E H ++ V FHP + +AS +D
Sbjct: 271 WNLDSKTCVQEITSHRKKFDESIHDVAFHPQKPYIASAGAD 393
Score = 43.5 bits (101), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 23/99 (23%), Positives = 48/99 (48%), Gaps = 4/99 (4%)
Frame = +1
Query: 38 TGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKI 97
T +D + + N I ++ H V S+ ++ +++GS SIR+W+L++
Sbjct: 115 TAHEDRHIRFFDNNTGKLIHAMVAHLDSVTSLAVDPNGLYLLSGSHDCSIRLWNLDSKTC 294
Query: 98 LRTLMGHKA----NICSLDFHPYGEFVASGSQDTNIKLW 132
++ + H+ +I + FHP ++AS D K++
Sbjct: 295 VQEITSHRKKFDESIHDVAFHPQKPYIASAGADALAKVF 411
Score = 41.6 bits (96), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 26/95 (27%), Positives = 41/95 (43%), Gaps = 4/95 (4%)
Frame = +1
Query: 164 SAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQV 223
+A +D ++ +D GK++ H V + PN L SGS D +IR W+L+
Sbjct: 115 TAHEDRHIRFFDNNTGKLIHAMVAHLDSVTSLAVDPNGLYLLSGSHDCSIRLWNLDSKTC 294
Query: 224 VSCIEGE----PGPVRSVLFNPDGCCLYSGCQDSL 254
V I + V F+P + S D+L
Sbjct: 295 VQEITSHRKKFDESIHDVAFHPQKPYIASAGADAL 399
Score = 39.7 bits (91), Expect = 0.004, Method: Composition-based stats.
Identities = 16/50 (32%), Positives = 29/50 (58%)
Frame = +1
Query: 13 LQEIVAHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGH 62
+ +VAH +V+SL + +G L +G DC + LW+++ C+ +T H
Sbjct: 169 IHAMVAHLDSVTSLAV-DPNGLYLLSGSHDCSIRLWNLDSKTCVQEITSH 315
Score = 35.4 bits (80), Expect = 0.068, Method: Composition-based stats.
Identities = 23/88 (26%), Positives = 41/88 (46%), Gaps = 1/88 (1%)
Frame = +1
Query: 178 AGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSV 237
AG+ +S P + HP + + DR IRF+D +++ + V S+
Sbjct: 31 AGRTLSM*YKWQQPDQLHHQHPTMPITITAHEDRHIRFFDNNTGKLIHAMVAHLDSVTSL 210
Query: 238 LFNPDGCCLYSGCQD-SLRVYGWEPERC 264
+P+G L SG D S+R++ + + C
Sbjct: 211 AVDPNGLYLLSGSHDCSIRLWNLDSKTC 294
>26939
Length = 388
Score = 53.9 bits (128), Expect = 2e-07, Method: Composition-based stats.
Identities = 23/58 (39%), Positives = 35/58 (60%)
Frame = +2
Query: 78 IVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIR 135
+V+ S +IRVWDL + ++TL H+ S+DFH +V SGS D +K+W+ R
Sbjct: 11 LVSASDDKTIRVWDLRNKRCMKTLYAHQHFCTSIDFHKAHPYVISGSVDQTVKVWECR 184
Score = 50.8 bits (120), Expect = 2e-06, Method: Composition-based stats.
Identities = 21/59 (35%), Positives = 34/59 (57%)
Frame = +2
Query: 159 GKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWD 217
GK+L SA+DD T+++WDL + M H ++FH + SGS D+T++ W+
Sbjct: 2 GKYLVSASDDKTIRVWDLRNKRCMKTLYAHQHFCTSIDFHKAHPYVISGSVDQTVKVWE 178
Score = 43.5 bits (101), Expect = 3e-04, Method: Composition-based stats.
Identities = 18/59 (30%), Positives = 31/59 (52%)
Frame = +2
Query: 117 GEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWD 175
G+++ S S D I++WD+R K C+ H + F ++ S + D TVK+W+
Sbjct: 2 GKYLVSASDDKTIRVWDLRNKRCMKTLYAHQHFCTSIDFHKAHPYVISGSVDQTVKVWE 178
>37180
Length = 681
Score = 51.6 bits (122), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 25/77 (32%), Positives = 40/77 (51%), Gaps = 1/77 (1%)
Frame = +1
Query: 101 LMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFR-YRGHSQAVRCLRFSPDG 159
L GH + + HP V + S+D +LWD R + ++GH+Q V F+ G
Sbjct: 7 LNGHDQELSDVHAHPTQRLVVTSSKDMTFRLWDFRDSALLVNVFQGHTQPVTSAVFAS-G 183
Query: 160 KWLASAADDHTVKLWDL 176
+ S +DD TV++WD+
Sbjct: 184 DKVVSGSDDRTVRVWDM 234
Score = 50.1 bits (118), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 29/97 (29%), Positives = 50/97 (51%), Gaps = 2/97 (2%)
Frame = +1
Query: 145 GHSQAVRCLRFSPDGKWLASAADDHTVKLWDL-TAGKMMSEFPGHTGPVNVVEFHPNEYL 203
GH Q + + P + + +++ D T +LWD + +++ F GHT PV F + +
Sbjct: 13 GHDQELSDVHAHPTQRLVVTSSKDMTFRLWDFRDSALLVNVFQGHTQPVTSAVFASGDKV 192
Query: 204 LASGSSDRTIRFWDLEKFQV-VSCIEGEPGPVRSVLF 239
+ SGS DRT+R WD+ + ++ I + R V F
Sbjct: 193 V-SGSDDRTVRVWDMRNMRSPIATIRTDSAVNRFV*F 300
Score = 47.4 bits (111), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 24/78 (30%), Positives = 40/78 (51%), Gaps = 1/78 (1%)
Frame = +1
Query: 59 LTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLE-AAKILRTLMGHKANICSLDFHPYG 117
L GH + V + + L+V S+ + R+WD +A ++ GH + S F G
Sbjct: 7 LNGHDQELSDVHAHPTQRLVVTSSKDMTFRLWDFRDSALLVNVFQGHTQPVTSAVF-ASG 183
Query: 118 EFVASGSQDTNIKLWDIR 135
+ V SGS D +++WD+R
Sbjct: 184 DKVVSGSDDRTVRVWDMR 237
Score = 40.8 bits (94), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 24/73 (32%), Positives = 38/73 (52%), Gaps = 2/73 (2%)
Frame = +1
Query: 187 GHTGPVNVVEFHPNEYLLASGSSDRTIRFWDL-EKFQVVSCIEGEPGPVRSVLFNPDGCC 245
GH ++ V HP + L+ + S D T R WD + +V+ +G PV S +F G
Sbjct: 13 GHDQELSDVHAHPTQRLVVTSSKDMTFRLWDFRDSALLVNVFQGHTQPVTSAVF-ASGDK 189
Query: 246 LYSGCQD-SLRVY 257
+ SG D ++RV+
Sbjct: 190 VVSGSDDRTVRVW 228
>31864
Length = 545
Score = 49.7 bits (117), Expect = 4e-06, Method: Composition-based stats.
Identities = 39/140 (27%), Positives = 56/140 (40%), Gaps = 15/140 (10%)
Frame = +2
Query: 90 WDL-EAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQ 148
WD+ + K++ + + H I + G + S+DT KL+D C+ Y+ +
Sbjct: 2 WDVRKGQKVVDSGVDHTGGINDMQLSKDGTMFVTASKDTTAKLFDSESLMCLKTYKTE-R 178
Query: 149 AVRCLRFSP--DGKWLASAADDHTVKLWDLTAGKMMSEF------------PGHTGPVNV 194
V SP D L D V AGK S F GH GP+N
Sbjct: 179 PVNSAAISPILDHVVLGGGQDAMEVTTTSTKAGKFDSRFFHLIYEEEFARLKGHFGPINS 358
Query: 195 VEFHPNEYLLASGSSDRTIR 214
+ FHP+ ASG D +R
Sbjct: 359 LAFHPDGKSYASGGEDGFVR 418
Score = 43.5 bits (101), Expect = 2e-04, Method: Composition-based stats.
Identities = 34/138 (24%), Positives = 59/138 (42%), Gaps = 15/138 (10%)
Frame = +2
Query: 132 WDIRR-KGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTG 190
WD+R+ + V H+ + ++ S DG +A+ D T KL+D + + +
Sbjct: 2 WDVRKGQKVVDSGVDHTGGINDMQLSKDGTMFVTASKDTTAKLFDSESLMCLKTYKTER- 178
Query: 191 PVNVVEFHP--NEYLLASGSSDRTI------------RFWDLEKFQVVSCIEGEPGPVRS 236
PVN P + +L G + RF+ L + + ++G GP+ S
Sbjct: 179 PVNSAAISPILDHVVLGGGQDAMEVTTTSTKAGKFDSRFFHLIYEEEFARLKGHFGPINS 358
Query: 237 VLFNPDGCCLYSGCQDSL 254
+ F+PDG SG +D
Sbjct: 359 LAFHPDGKSYASGGEDGF 412
Score = 36.2 bits (82), Expect = 0.040, Method: Composition-based stats.
Identities = 34/141 (24%), Positives = 59/141 (41%), Gaps = 15/141 (10%)
Frame = +2
Query: 48 WSINKPNCIM-SLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKA 106
W + K ++ S HT + ++L+ + V S+ + +++D E+ L+T +
Sbjct: 2 WDVRKGQKVVDSGVDHTGGINDMQLSKDGTMFVTASKDTTAKLFDSESLMCLKTYKTERP 181
Query: 107 NICSLDFHP-YGEFVASGSQD--------TNIKLWDIRRKGCVF-----RYRGHSQAVRC 152
+ S P V G QD T +D R ++ R +GH +
Sbjct: 182 -VNSAAISPILDHVVLGGGQDAMEVTTTSTKAGKFDSRFFHLIYEEEFARLKGHFGPINS 358
Query: 153 LRFSPDGKWLASAADDHTVKL 173
L F PDGK AS +D V++
Sbjct: 359 LAFHPDGKSYASGGEDGFVRV 421
>19863
Length = 502
Score = 49.7 bits (117), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 23/63 (36%), Positives = 35/63 (55%)
Frame = +1
Query: 158 DGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWD 217
DG L S + D ++ +WD+ G GH G VN V F ++ L S S+D T+R W+
Sbjct: 4 DGLQLVSGSSDMSIVVWDVENGVQKLRLQGHAGWVNDVHFSQDQCWLLSCSNDNTVRIWN 183
Query: 218 LEK 220
+E+
Sbjct: 184 IEE 192
Score = 47.8 bits (112), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 22/60 (36%), Positives = 36/60 (60%)
Frame = +1
Query: 117 GEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDL 176
G + SGS D +I +WD+ R +GH+ V + FS D WL S ++D+TV++W++
Sbjct: 7 GLQLVSGSSDMSIVVWDVENGVQKLRLQGHAGWVNDVHFSQDQCWLLSCSNDNTVRIWNI 186
Score = 37.4 bits (85), Expect = 0.017, Method: Compositional matrix adjust.
Identities = 17/73 (23%), Positives = 35/73 (47%)
Frame = +1
Query: 33 GRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDL 92
G L +G D + +W + + L GH V V + + +++ S ++R+W++
Sbjct: 7 GLQLVSGSSDMSIVVWDVENGVQKLRLQGHAGWVNDVHFSQDQCWLLSCSNDNTVRIWNI 186
Query: 93 EAAKILRTLMGHK 105
E + + +M HK
Sbjct: 187 EESDQIPIVMEHK 225
Score = 36.6 bits (83), Expect = 0.033, Method: Compositional matrix adjust.
Identities = 29/96 (30%), Positives = 45/96 (46%), Gaps = 1/96 (1%)
Frame = +1
Query: 204 LASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVLFNPDGCCLYSGCQD-SLRVYGWEPE 262
L SGSSD +I WD+E ++G G V V F+ D C L S D ++R++ E
Sbjct: 16 LVSGSSDMSIVVWDVENGVQKLRLQGHAGWVNDVHFSQDQCWLLSCSNDNTVRIWNIEES 195
Query: 263 RCFDVVLVNWGKVADLAICNDQLIGVAFSQSNVSSY 298
+V+ + + L + G FS S V ++
Sbjct: 196 DQIPIVMEH-KRAQGLKVTKCSKCGKPFSMSEVENF 300
>00825
Length = 1821
Score = 48.9 bits (115), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 34/142 (23%), Positives = 62/142 (43%), Gaps = 3/142 (2%)
Frame = -2
Query: 80 AGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGC 139
+G+ G + W+L ++ + H + + H G++ S D IK W + +G
Sbjct: 1820 SGACDGELICWNLPKQQMACRVQAHDGIVHGMAAHSSGQYFFSCGSDKTIKQWSLDPEGT 1641
Query: 140 VFRYRGHSQAVRCLRFSPDGKWLAS--AADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEF 197
+ ++ +C+ S D W V +WD + M F V+ V+F
Sbjct: 1640 IAPEPVNTLLAKCIYTSLDHHWKDDIFVTSGSRVDVWDEKRSEPMRSFSWGVESVHHVKF 1461
Query: 198 HPNE-YLLASGSSDRTIRFWDL 218
+P E YLL + + DR+I +D+
Sbjct: 1460 NPVETYLLGAAAHDRSILLYDM 1395
Score = 33.5 bits (75), Expect = 0.24, Method: Compositional matrix adjust.
Identities = 30/120 (25%), Positives = 51/120 (42%), Gaps = 10/120 (8%)
Frame = -2
Query: 164 SAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQV 223
S A D + W+L +M H G V+ + H + S SD+TI+ W L+
Sbjct: 1820 SGACDGELICWNLPKQQMACRVQAHDGIVHGMAAHSSGQYFFSCGSDKTIKQWSLDPEGT 1641
Query: 224 VSCIEGEPGPVRSVLFNPDGCCLYSGC----QDSL------RVYGWEPERCFDVVLVNWG 273
++ P PV ++L C+Y+ +D + RV W+ +R + +WG
Sbjct: 1640 IA-----PEPVNTLL----AKCIYTSLDHHWKDDIFVTSGSRVDVWDEKRSEPMRSFSWG 1488
>15337
Length = 860
Score = 48.5 bits (114), Expect = 9e-06, Method: Compositional matrix adjust.
Identities = 25/101 (24%), Positives = 50/101 (49%)
Frame = -1
Query: 97 ILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFS 156
+ R ++G A I F P ++A QD ++++++ + + + + C+ +S
Sbjct: 350 LYRWVVGTGA-ISEFAFSPCSRYLAVVGQDGHLRVFNYNSMELIGTMKSYFGGLLCVCWS 174
Query: 157 PDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEF 197
PDGK++ + +D V +W +++ GH VNVV F
Sbjct: 173 PDGKYIVTGGEDDLVTVWSFHEKRVVCRGHGHKSWVNVVAF 51
Score = 33.9 bits (76), Expect = 0.24, Method: Compositional matrix adjust.
Identities = 23/104 (22%), Positives = 42/104 (40%), Gaps = 2/104 (1%)
Frame = -1
Query: 13 LQEIVAHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLN 72
L V +S S R LA G D + +++ N I ++ + + V +
Sbjct: 350 LYRWVVGTGAISEFAFSPCS-RYLAVVGQDGHLRVFNYNSMELIGTMKSYFGGLLCVCWS 174
Query: 73 TPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKA--NICSLDFH 114
+ IV G + + VW +++ GHK+ N+ + D H
Sbjct: 173 PDGKYIVTGGEDDLVTVWSFHEKRVVCRGHGHKSWVNVVAFDIH 42
>27806
Length = 419
Score = 48.5 bits (114), Expect = 9e-06, Method: Compositional matrix adjust.
Identities = 19/55 (34%), Positives = 31/55 (56%)
Frame = -1
Query: 162 LASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFW 216
+ +A+ DHT +++ + G + + GH G VN V FHP + L+ + S D T W
Sbjct: 380 IGTASADHTARIYSIETGACVLTYGGHQGSVNAVRFHPGQDLVLTASGDHTAHVW 216
Score = 45.1 bits (105), Expect = 8e-05, Method: Compositional matrix adjust.
Identities = 19/61 (31%), Positives = 30/61 (49%)
Frame = -1
Query: 114 HPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKL 173
HP + + S D +++ I CV Y GH +V +RF P + +A+ DHT +
Sbjct: 389 HP---IIGTASADHTARIYSIETGACVLTYGGHQGSVNAVRFHPGQDLVLTASGDHTAHV 219
Query: 174 W 174
W
Sbjct: 218 W 216
Score = 35.4 bits (80), Expect = 0.068, Method: Compositional matrix adjust.
Identities = 14/56 (25%), Positives = 28/56 (50%)
Frame = -1
Query: 35 LLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVW 90
++ T D ++SI C+++ GH V +VR + ++L++ S + VW
Sbjct: 383 IIGTASADHTARIYSIETGACVLTYGGHQGSVNAVRFHPGQDLVLTASGDHTAHVW 216
Score = 33.9 bits (76), Expect = 0.19, Method: Compositional matrix adjust.
Identities = 14/56 (25%), Positives = 28/56 (50%)
Frame = -1
Query: 77 LIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLW 132
+I S + R++ +E + T GH+ ++ ++ FHP + V + S D +W
Sbjct: 383 IIGTASADHTARIYSIETGACVLTYGGHQGSVNAVRFHPGQDLVLTASGDHTAHVW 216
>26107
Length = 1338
Score = 47.4 bits (111), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 37/151 (24%), Positives = 68/151 (45%), Gaps = 1/151 (0%)
Frame = -3
Query: 72 NTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEF-VASGSQDTNIK 130
N + L +G Q+ + +WD+E + T +GHK ++ S+ P ASG++D +I
Sbjct: 1054 NDSQCLTASGDQT--VALWDVETTTKVTTFIGHKCSVRSVASCPSSPAQCASGARDGHIM 881
Query: 131 LWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTG 190
LWD R V + R H + + P + A + G M ++
Sbjct: 880 LWDSR----VNKKREHQPCSQVHQVCPQSGHQSKPAKHRRIHRAAGPKGVMDTQ-----Q 728
Query: 191 PVNVVEFHPNEYLLASGSSDRTIRFWDLEKF 221
V V + + +++SG++D ++ WD K+
Sbjct: 727 SVTCVLYQTDNLIISSGANDGCVKMWDTRKW 635
Score = 42.0 bits (97), Expect = 8e-04, Method: Compositional matrix adjust.
Identities = 59/268 (22%), Positives = 104/268 (38%), Gaps = 59/268 (22%)
Frame = -3
Query: 8 KTAWKLQEIVAHASNVSSLVLGKASGRLLATGGDDCRVNLWS--INKP---------NCI 56
+T K+ + H +V S+ +S A+G D + LW +NK + +
Sbjct: 997 ETTTKVTTFIGHKCSVRSVASCPSSPAQCASGARDGHIMLWDSRVNKKREHQPCSQVHQV 818
Query: 57 MSLTGHTS-PVESVRLN---------------------TPEELIVAGSQSGSIRVWD--- 91
+GH S P + R++ T +I +G+ G +++WD
Sbjct: 817 CPQSGHQSKPAKHRRIHRAAGPKGVMDTQQSVTCVLYQTDNLIISSGANDGCVKMWDTRK 638
Query: 92 ---------------LEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDI-- 134
+ +R L G I ++ P+ + D + + +
Sbjct: 637 WYTNTTTSLPVPVHTFDYPGHMRRLKG----IVTMCMDPWKSQLFVSYTDNKVYRYQLAG 470
Query: 135 -RRKGCVFRYRGHSQA---VRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEF-PGHT 189
R+ + Y GH VRC SPDGK+L S + +T +W++ F GHT
Sbjct: 469 QYREPQEYVYAGHRNDTFFVRCA-ISPDGKYLLSGSGRNTGVIWEVDKPNKRPLFLIGHT 293
Query: 190 GPVNVVEFHPNEYL-LASGSSDRTIRFW 216
V+ V++ + LA+ S DR++R W
Sbjct: 292 EDVSAVDWCSTDVCKLATVSDDRSLRIW 209
Score = 37.7 bits (86), Expect = 0.014, Method: Compositional matrix adjust.
Identities = 25/79 (31%), Positives = 36/79 (45%), Gaps = 1/79 (1%)
Frame = -3
Query: 140 VFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHP 199
V R+ H+ AV + + +A+ D TV LWD+ ++ F GH V V P
Sbjct: 1108 VHRWXAHNNAVFDYSWISNDSQCLTASGDQTVALWDVETTTKVTTFIGHKCSVRSVASCP 929
Query: 200 NE-YLLASGSSDRTIRFWD 217
+ ASG+ D I WD
Sbjct: 928 SSPAQCASGARDGHIMLWD 872
Score = 36.6 bits (83), Expect = 0.035, Method: Compositional matrix adjust.
Identities = 36/140 (25%), Positives = 55/140 (39%), Gaps = 2/140 (1%)
Frame = -3
Query: 38 TGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRL--NTPEELIVAGSQSGSIRVWDLEAA 95
T D V LW + + + GH V SV ++P + +G++ G I +WD
Sbjct: 1036 TASGDQTVALWDVETTTKVTTFIGHKCSVRSVASCPSSPAQC-ASGARDGHIMLWDSRVN 860
Query: 96 KILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRF 155
K + CS + SG Q K I R Q+V C+ +
Sbjct: 859 K------KREHQPCS---QVHQVCPQSGHQSKPAKHRRIHRAAGPKGVMDTQQSVTCVLY 707
Query: 156 SPDGKWLASAADDHTVKLWD 175
D ++S A+D VK+WD
Sbjct: 706 QTDNLIISSGANDGCVKMWD 647
>21921
Length = 1341
Score = 47.4 bits (111), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 22/61 (36%), Positives = 36/61 (59%)
Frame = -1
Query: 143 YRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEY 202
Y+GH+ VR + P G+WL S +DD T++ W++++G+ M G V V ++PN
Sbjct: 495 YKGHTGIVRSICPDPTGQWLVSGSDDGTIRFWEVSSGRCMKTL-QVGGCVTSVAWNPNPS 319
Query: 203 L 203
L
Sbjct: 318 L 316
Score = 40.4 bits (93), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 34/115 (29%), Positives = 56/115 (48%), Gaps = 2/115 (1%)
Frame = -1
Query: 185 FPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVLFNPD-G 243
+ GHTG V + P L SGS D TIRFW++ + + ++ G V SV +NP+
Sbjct: 495 YKGHTGIVRSICPDPTGQWLVSGSDDGTIRFWEVSSGRCMKTLQVG-GCVTSVAWNPNPS 319
Query: 244 CCLYSGCQDSLRVYGWEPERCFDVVLVNWGKVADLAICN-DQLIGVAFSQSNVSS 297
C+ + ++ V+L+N G L + N D+L+ + Q++ SS
Sbjct: 318 LCVVAATLNTT------------VLLINPGLGDKLVVSNTDKLLLASEDQASSSS 190
Score = 34.3 bits (77), Expect = 0.14, Method: Compositional matrix adjust.
Identities = 14/41 (34%), Positives = 26/41 (63%)
Frame = -1
Query: 61 GHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTL 101
GHT V S+ + + +V+GS G+IR W++ + + ++TL
Sbjct: 489 GHTGIVRSICPDPTGQWLVSGSDDGTIRFWEVSSGRCMKTL 367
Score = 31.6 bits (70), Expect = 0.92, Method: Compositional matrix adjust.
Identities = 16/67 (23%), Positives = 33/67 (49%)
Frame = -1
Query: 74 PEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWD 133
P++L+ + +R + A + + GH + S+ P G+++ SGS D I+ W+
Sbjct: 567 PQDLLPKLPKPKDLRPFPTTQALVYK---GHTGIVRSICPDPTGQWLVSGSDDGTIRFWE 397
Query: 134 IRRKGCV 140
+ C+
Sbjct: 396 VSSGRCM 376
>11915
Length = 737
Score = 47.4 bits (111), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 31/100 (31%), Positives = 51/100 (51%), Gaps = 5/100 (5%)
Frame = +1
Query: 72 NTPEELIVA-GSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEF-VASGSQDTNI 129
N L++A G SG I++W+ E K+L +M HKA + L F + S S D +
Sbjct: 430 NDSSTLVLATGHVSGRIKLWNCETGKLLIEMMDHKATVHDLHFAADNSLCLMSASHDGTV 609
Query: 130 KLWDIRRKGCVFRY---RGHSQAVRCLRFSPDGKWLASAA 166
KLW+ +G Y R +++ R+S D +++A+A
Sbjct: 610 KLWEFDDQGDCNMYLTLRTNAKHAFSCRWSHDRRYVATAG 729
Score = 35.8 bits (81), Expect = 0.061, Method: Compositional matrix adjust.
Identities = 16/50 (32%), Positives = 26/50 (52%), Gaps = 1/50 (2%)
Frame = +1
Query: 171 VKLWDLTAGKMMSEFPGHTGPVNVVEFHP-NEYLLASGSSDRTIRFWDLE 219
+KLW+ GK++ E H V+ + F N L S S D T++ W+ +
Sbjct: 478 IKLWNCETGKLLIEMMDHKATVHDLHFAADNSLCLMSASHDGTVKLWEFD 627
Score = 32.3 bits (72), Expect = 0.59, Method: Compositional matrix adjust.
Identities = 21/94 (22%), Positives = 43/94 (45%), Gaps = 1/94 (1%)
Frame = +1
Query: 1 MATPVVTKTAWKLQEIVAHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLT 60
++T K WK Q+ ++ S+LVL ATG R+ LW+ ++ +
Sbjct: 382 ISTNNCYKQRWKRQQ----QNDSSTLVL--------ATGHVSGRIKLWNCETGKLLIEMM 525
Query: 61 GHTSPVESVRLNTPEEL-IVAGSQSGSIRVWDLE 93
H + V + L +++ S G++++W+ +
Sbjct: 526 DHKATVHDLHFAADNSLCLMSASHDGTVKLWEFD 627
>19140
Length = 573
Score = 46.2 bits (108), Expect = 4e-05, Method: Compositional matrix adjust.
Identities = 34/120 (28%), Positives = 51/120 (42%), Gaps = 1/120 (0%)
Frame = -3
Query: 98 LRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSP 157
L L GH N+ +L + G SGS D I+LW + ++ CV +R H + V L+ +
Sbjct: 508 LMKLKGHTDNVKALVLNRDGTQCLSGSSDGTIRLWSLGQQRCVATFRVHDEGVWALQANE 329
Query: 158 DGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNE-YLLASGSSDRTIRFW 216
L S DH V D+ PV +E P + L ++D I+ W
Sbjct: 328 SFTTLYSGGRDHQVWATDIKNPDNRELICEEKAPVLKLELTPTDPPSLWVATTDSCIKNW 149
Score = 43.1 bits (100), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 23/80 (28%), Positives = 40/80 (50%)
Frame = -3
Query: 56 IMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHP 115
+M L GHT V+++ LN ++GS G+IR+W L + + T H + +L +
Sbjct: 508 LMKLKGHTDNVKALVLNRDGTQCLSGSSDGTIRLWSLGQQRCVATFRVHDEGVWALQANE 329
Query: 116 YGEFVASGSQDTNIKLWDIR 135
+ SG +D + DI+
Sbjct: 328 SFTTLYSGGRDHQVWATDIK 269
Score = 40.4 bits (93), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 25/102 (24%), Positives = 45/102 (44%)
Frame = -3
Query: 140 VFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHP 199
+ + +GH+ V+ L + DG S + D T++LW L + ++ F H V ++ +
Sbjct: 508 LMKLKGHTDNVKALVLNRDGTQCLSGSSDGTIRLWSLGQQRCVATFRVHDEGVWALQANE 329
Query: 200 NEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVLFNP 241
+ L SG D + D++ I E PV + P
Sbjct: 328 SFTTLYSGGRDHQVWATDIKNPDNRELICEEKAPVLKLELTP 203
Score = 36.2 bits (82), Expect = 0.046, Method: Compositional matrix adjust.
Identities = 25/76 (32%), Positives = 36/76 (47%)
Frame = -3
Query: 177 TAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRS 236
T K+M + GHT V + + + SGSSD TIR W L + + V+ V +
Sbjct: 520 TCHKLM-KLKGHTDNVKALVLNRDGTQCLSGSSDGTIRLWSLGQQRCVATFRVHDEGVWA 344
Query: 237 VLFNPDGCCLYSGCQD 252
+ N LYSG +D
Sbjct: 343 LQANESFTTLYSGGRD 296
>34005
Length = 456
Score = 46.2 bits (108), Expect = 4e-05, Method: Compositional matrix adjust.
Identities = 31/98 (31%), Positives = 49/98 (50%), Gaps = 6/98 (6%)
Frame = +1
Query: 148 QAVRCLRFSPDGKWLASAADDHTVKLWDLTAGK---MMSEFPGHTGPVNVVEFHPNEYLL 204
Q V L +SPD +LAS ++D++V +WD T G + H V V + P + +
Sbjct: 115 QEVCGLSWSPDATFLASGSNDNSVNIWDSTLGMDVPPLHTLTSHQAAVKAVAWCPWQTRM 294
Query: 205 ---ASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVLF 239
G++DR IRFW+ V ++ + V SVL+
Sbjct: 295 LATGGGTNDRHIRFWNTNTGACVKAVDTQS-QVCSVLW 405
Score = 33.5 bits (75), Expect = 0.29, Method: Compositional matrix adjust.
Identities = 21/78 (26%), Positives = 36/78 (46%), Gaps = 6/78 (7%)
Frame = +1
Query: 108 ICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCV---FRYRGHSQAVRCLRFSP-DGKWLA 163
+C L + P F+ASGS D ++ +WD V H AV+ + + P + LA
Sbjct: 121 VCGLSWSPDATFLASGSNDNSVNIWDSTLGMDVPPLHTLTSHQAAVKAVAWCPWQTRMLA 300
Query: 164 SAA--DDHTVKLWDLTAG 179
+ +D ++ W+ G
Sbjct: 301 TGGGTNDRHIRFWNTNTG 354
Score = 32.3 bits (72), Expect = 0.66, Method: Compositional matrix adjust.
Identities = 20/83 (24%), Positives = 34/83 (40%), Gaps = 6/83 (7%)
Frame = +1
Query: 77 LIVAGSQSGSIRVWDLEAAKI---LRTLMGHKANICSLDFHPYGE---FVASGSQDTNIK 130
+ +GS S+ +WD L TL H+A + ++ + P+ G+ D +I+
Sbjct: 154 FLASGSNDNSVNIWDSTLGMDVPPLHTLTSHQAAVKAVAWCPWQTRMLATGGGTNDRHIR 333
Query: 131 LWDIRRKGCVFRYRGHSQAVRCL 153
W+ CV SQ L
Sbjct: 334 FWNTNTGACVKAVDTQSQVCSVL 402
>01598
Length = 1545
Score = 45.8 bits (107), Expect = 5e-05, Method: Compositional matrix adjust.
Identities = 56/195 (28%), Positives = 80/195 (41%), Gaps = 30/195 (15%)
Frame = +1
Query: 77 LIVAGSQSGSIRVWDLEAAKIL--------RTLMGHKAN-------ICSLDFHPYGEFVA 121
LI GS+ +IRVW L K + R G + I L +P E +
Sbjct: 106 LIATGSKDRTIRVWTLSQGKQIFMKKLPNQRREAGDTGSRFKVWLAIHWLKSNP--EQLV 279
Query: 122 SGSQDTNIKLWDIR-RKGCVFR------YRGHSQAVRCLRFS-PDGKWLASAADDHTVKL 173
S S ++ LW +R KG ++ YR H + V + S PD K L + A D V L
Sbjct: 280 SSSSGGDLLLWSLRYTKGQAYQTFQTSDYRPHMRPVFNICASGPDSKTLCTFAQDRQVVL 459
Query: 174 WDL---TAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEK----FQVVSC 226
WDL A M+ GH V P +A G D IR W++ + V +
Sbjct: 460 WDLETMEAVASMATLGGHVYCVRTSPIDPGR--VAVGVGDSMIRTWNMSNKTNPYDVTTL 633
Query: 227 IEGEPGPVRSVLFNP 241
+G V +V ++P
Sbjct: 634 WQGIKSKVTAVAWHP 678
Score = 40.8 bits (94), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 28/101 (27%), Positives = 50/101 (49%), Gaps = 3/101 (2%)
Frame = +1
Query: 123 GSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSP--DGKWLASAADDHTVKLWDLTAGK 180
G ++T++ L +R GHSQ V + +SP D + L S D +WD+ G
Sbjct: 1246 GDKETSLILTSLRE------LSGHSQRVTDMSWSPHHDAR-LVSVGYDAEAFVWDVQKGT 1404
Query: 181 MMSEFPGHTGPVNVVEFHP-NEYLLASGSSDRTIRFWDLEK 220
+++F GH G + +F + L+ +G SD ++ W + +
Sbjct: 1405 ALAQFKGHMGRLLTCQFSGLDPDLVMTGGSDASVHVWRVSQ 1527
Score = 33.5 bits (75), Expect = 0.30, Method: Compositional matrix adjust.
Identities = 18/82 (21%), Positives = 40/82 (48%), Gaps = 2/82 (2%)
Frame = +1
Query: 98 LRTLMGHKANICSLDFHPYGEF-VASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFS 156
LR L GH + + + P+ + + S D +WD+++ + +++GH + +FS
Sbjct: 1279 LRELSGHSQRVTDMSWSPHHDARLVSVGYDAEAFVWDVQKGTALAQFKGHMGRLLTCQFS 1458
Query: 157 P-DGKWLASAADDHTVKLWDLT 177
D + + D +V +W ++
Sbjct: 1459 GLDPDLVMTGGSDASVHVWRVS 1524
Score = 32.0 bits (71), Expect = 0.86, Method: Compositional matrix adjust.
Identities = 16/79 (20%), Positives = 34/79 (43%), Gaps = 1/79 (1%)
Frame = +1
Query: 13 LQEIVAHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLN 72
L+E+ H+ V+ + L + G D +W + K + GH + + + +
Sbjct: 1279 LRELSGHSQRVTDMSWSPHHDARLVSVGYDAEAFVWDVQKGTALAQFKGHMGRLLTCQFS 1458
Query: 73 TPE-ELIVAGSQSGSIRVW 90
+ +L++ G S+ VW
Sbjct: 1459 GLDPDLVMTGGSDASVHVW 1515
Score = 28.9 bits (63), Expect = 7.6, Method: Compositional matrix adjust.
Identities = 16/84 (19%), Positives = 36/84 (42%), Gaps = 2/84 (2%)
Frame = +1
Query: 56 IMSLTGHTSPVESVRLNTPEEL-IVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFH 114
+ L+GH+ V + + + +V+ VWD++ L GH + + F
Sbjct: 1279 LRELSGHSQRVTDMSWSPHHDARLVSVGYDAEAFVWDVQKGTALAQFKGHMGRLLTCQFS 1458
Query: 115 PYG-EFVASGSQDTNIKLWDIRRK 137
+ V +G D ++ +W + ++
Sbjct: 1459 GLDPDLVMTGGSDASVHVWRVSQQ 1530
>30295
Length = 593
Score = 45.4 bits (106), Expect = 7e-05, Method: Compositional matrix adjust.
Identities = 33/123 (26%), Positives = 53/123 (43%), Gaps = 4/123 (3%)
Frame = +2
Query: 99 RTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPD 158
RTL H A I ++ + + S SQD + +WD V S V ++P
Sbjct: 227 RTLRXHLAKIYAMHWATDSRNLVSASQDGKLIVWDGYTTNKVHAIPLRSSWVMTCAYAPS 406
Query: 159 GKWLASAADDHTVKLWDLTAG----KMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIR 214
G ++A D+ ++ L ++ E PGHTG ++ F + ++ S S D T
Sbjct: 407 GGYVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFIDDNQIVTS-SGDMTCA 583
Query: 215 FWD 217
WD
Sbjct: 584 LWD 592
>21960
Length = 756
Score = 43.1 bits (100), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 27/75 (36%), Positives = 36/75 (48%), Gaps = 1/75 (1%)
Frame = +1
Query: 113 FHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQA-VRCLRFSPDGKWLASAADDHTV 171
F P+ E + SGS D NI WD + +G V CL P LA++ DH V
Sbjct: 388 FGPHSEHIISGSDDGNIFYWDKNTEAVTNFMKGDDAGVVNCLEQHPTMPVLATSGLDHNV 567
Query: 172 KLWDLTAGKMMSEFP 186
K+W +A K +E P
Sbjct: 568 KIWTPSA-KPETEVP 609
Score = 37.7 bits (86), Expect = 0.015, Method: Compositional matrix adjust.
Identities = 18/58 (31%), Positives = 30/58 (51%), Gaps = 1/58 (1%)
Frame = +1
Query: 76 ELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICS-LDFHPYGEFVASGSQDTNIKLW 132
E I++GS G+I WD + + G A + + L+ HP +A+ D N+K+W
Sbjct: 403 EHIISGSDDGNIFYWDKNTEAVTNFMKGDDAGVVNCLEQHPTMPVLATSGLDHNVKIW 576
Score = 35.0 bits (79), Expect = 0.10, Method: Compositional matrix adjust.
Identities = 19/67 (28%), Positives = 30/67 (44%), Gaps = 1/67 (1%)
Frame = +1
Query: 151 RCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGH-TGPVNVVEFHPNEYLLASGSS 209
R F P + + S +DD + WD + + G G VN +E HP +LA+
Sbjct: 376 RVNFFGPHSEHIISGSDDGNIFYWDKNTEAVTNFMKGDDAGVVNCLEQHPTMPVLATSGL 555
Query: 210 DRTIRFW 216
D ++ W
Sbjct: 556 DHNVKIW 576
Score = 28.5 bits (62), Expect = 8.8, Method: Compositional matrix adjust.
Identities = 38/172 (22%), Positives = 72/172 (41%), Gaps = 16/172 (9%)
Frame = +1
Query: 83 QSGSIRVWDLEA---AKILR--TLMGHKANICSLDFHPYG-EFVASGSQDTNIKLWDIRR 136
+ +++ +DL + +LR T + + S+ HP+ EF SGS D ++++D R+
Sbjct: 1 EDSTVKHFDLRSNCCTTMLRCYTKENRRVRLFSIAHHPFASEFCISGSDD-KLRVYDKRK 177
Query: 137 KGCVFRYRGHSQA----VRCLRFSPDGKWLASAADDHTVKLW--DLTAGKMMSEF--PGH 188
+ C ++ G + ++ D + L G+ +S H
Sbjct: 178 LDKTVHEMSPKDTKVSQITCAVYNHSGSEILASYSDAAIYLL*QPQLQGRRISALLRRPH 357
Query: 189 TGPVN--VVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVL 238
P + V F P+ + SGS D I +WD V + ++G+ V + L
Sbjct: 358 K*PYHQRVNFFGPHSEHIISGSDDGNIFYWDKNTEAVTNFMKGDDAGVVNCL 513
>04358
Length = 2430
Score = 42.0 bits (97), Expect = 7e-04, Method: Compositional matrix adjust.
Identities = 33/134 (24%), Positives = 59/134 (44%), Gaps = 11/134 (8%)
Frame = +1
Query: 119 FVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRF-SPDGKWLASAADDHTVKLWD-- 175
VA+ S + ++L+ R GH + +RF D + +A+ DHTV++WD
Sbjct: 1336 LVAAASSNFMVRLYSRCRLAQTNTLTGHDDVISSIRFLHTDPGLIMTASHDHTVRIWDPR 1515
Query: 176 LTAGKMMSEFPGHTG---PVNVVEFHPNEYLLASGSS----DRTIRFWDLEKFQVVSCIE 228
+ K + F G V + + ++ +L +G+ D + FWD K +++ C E
Sbjct: 1516 ASVSKEVQRFSGEQNTKCSVLSCDVNISDRVLCAGTEMSNDDAYLLFWDRRKDKLLGCYE 1695
Query: 229 -GEPGPVRSVLFNP 241
+ V F P
Sbjct: 1696 DSHHDDITQVHFGP 1737
Score = 38.5 bits (88), Expect = 0.008, Method: Compositional matrix adjust.
Identities = 41/189 (21%), Positives = 79/189 (41%), Gaps = 20/189 (10%)
Frame = +1
Query: 18 AHASNVSSLVLGKASGRLLATGGDDCRVNLWSI---NKPNCIMSLTGHTSPVESVRLNTP 74
+H +++ + G S + L TG D VN++ + + + +MS + VE P
Sbjct: 1699 SHHDDITQVHFGPTSEKTLLTGSTDGLVNVFDVMQTTEDDALMSTYNTEATVERAGWCGP 1878
Query: 75 E-ELIVAGSQSGSIRVWDLEAAKILRTLMGHKANI---CSLDFH----PYGEFVA----- 121
+ + + A + S VWD E + ++ L + + C D+ P + +
Sbjct: 1879 QSQQVYAITHMLSWHVWDTEKDEDVQQLTDLEQKLQGQCQADYLVDCIPANQSTSPPCLV 2058
Query: 122 SGSQDTNIKLWDIRRKGCVFRYR----GHSQAVRCLRFSPDGKWLASAADDHTVKLWDLT 177
+G+ ++ + D+ V R GH+ VRCL + + L + +D + LW
Sbjct: 2059 AGTHTGDLHVLDLSDLEEVKVVRSLSGGHTDTVRCLHWDKQTQTLVTGGEDSMLCLWSSD 2238
Query: 178 AGKMMSEFP 186
A + S P
Sbjct: 2239 ASGIQSPAP 2265
>21763
Length = 923
Score = 42.0 bits (97), Expect = 9e-04, Method: Compositional matrix adjust.
Identities = 39/157 (24%), Positives = 68/157 (43%), Gaps = 4/157 (2%)
Frame = +1
Query: 19 HASNVSSLVLGKASGRLLAT---GGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPE 75
H VS V A G AT GD V ++K + + ++ V+ +
Sbjct: 181 HPKEVSK-VTWHAKGDYFATVMPKGDKMSVLFHLLSKKHSQSPFSQSKGLIQCVKFHPLR 357
Query: 76 ELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIR 135
+ SQ +R+++L + ++ L + I S+D HP G+ V GS D +D+
Sbjct: 358 PIFFVASQR-FVRIYNLLTQQFVKKLQTNCKWISSMDVHPGGDNVIIGSYDCKSCWFDLD 534
Query: 136 RKGCVFR-YRGHSQAVRCLRFSPDGKWLASAADDHTV 171
++ R H +AVR + + ASA+DD ++
Sbjct: 535 LSTKPYKILRHHKRAVRHVSYHHRYPLFASASDDGSI 645
>16105
Length = 960
Score = 42.0 bits (97), Expect = 9e-04, Method: Compositional matrix adjust.
Identities = 33/122 (27%), Positives = 63/122 (51%), Gaps = 10/122 (8%)
Frame = -2
Query: 145 GHSQAVRCLRFSP-DGKWLASAADDHTVKLWDLTAGKMMS-------EFPGHTGPVNVVE 196
GH AV +++ P + +ASA+DD TVK+W + +++ + GH ++
Sbjct: 581 GHKGAVLDIQWCPHNDNVIASASDDCTVKVWQIPDSGLVTNLTDPVVDLVGHQKRCCLIV 402
Query: 197 FHPN-EYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVLFNPDGCCLYSGCQD-SL 254
+HP+ + +L S +D I FW++ + + ++ P + + FN +G L C+D L
Sbjct: 401 WHPSAQNVLVSAGADNKILFWNVGTGEPMLEVD-VPDMIYCMSFNFNGSRLVCTCKDKKL 225
Query: 255 RV 256
R+
Sbjct: 224 RI 219
Score = 40.0 bits (92), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 43/225 (19%), Positives = 85/225 (37%), Gaps = 13/225 (5%)
Frame = -2
Query: 6 VTKTAWKLQEIVAHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSP 65
+T+T+W+ + V+ + G L RV ++ P + GH
Sbjct: 728 ITRTSWESTYCAVNPKFVAVMTEAAGGGAFLVLPLS--RVGRVPVDNP----LVAGHKGA 567
Query: 66 VESVR-LNTPEELIVAGSQSGSIRVWDLEAAKILRTL-------MGHKANICSLDFHPYG 117
V ++ + +I + S +++VW + + ++ L +GH+ C + +HP
Sbjct: 566 VLDIQWCPHNDNVIASASDDCTVKVWQIPDSGLVTNLTDPVVDLVGHQKRCCLIVWHPSA 387
Query: 118 EFV-ASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDL 176
+ V S D I W++ + + C+ F+ +G L D +++ D
Sbjct: 386 QNVLVSAGADNKILFWNVGTGEPMLEVD-VPDMIYCMSFNFNGSRLVCTCKDKKLRIIDS 210
Query: 177 TAGKMMSEFPGHTG--PVNVVEFHPNEYLLASGS--SDRTIRFWD 217
+G ++ E H G P + S S+R WD
Sbjct: 209 HSGAVLKEGKCHDGAKPAQACYLKDGKVFTTGFSRMSERQYAIWD 75
>31384
Length = 474
Score = 40.8 bits (94), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 26/91 (28%), Positives = 45/91 (49%), Gaps = 5/91 (5%)
Frame = -1
Query: 107 NICSLDFHPYG---EFVASGSQDTNIKLWDIRRKGCVF--RYRGHSQAVRCLRFSPDGKW 161
++ L F P F+ SGS D + W++++ G + H+ V + +S DG
Sbjct: 270 SVSCLKFSPGALPSTFLISGSWDNKVSCWEVQQSGQTIPKAQQTHTGPVLDVDWSDDGTK 91
Query: 162 LASAADDHTVKLWDLTAGKMMSEFPGHTGPV 192
+ +A+ D T K+WDL + + M + H PV
Sbjct: 90 VFTASCDKTAKVWDLNSNQCM-QIAQHDAPV 1
Score = 38.9 bits (89), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 25/81 (30%), Positives = 44/81 (54%), Gaps = 5/81 (6%)
Frame = -1
Query: 149 AVRCLRFSPDG---KWLASAADDHTVKLWDLT-AGKMMSEFP-GHTGPVNVVEFHPNEYL 203
+V CL+FSP +L S + D+ V W++ +G+ + + HTGPV V++ +
Sbjct: 270 SVSCLKFSPGALPSTFLISGSWDNKVSCWEVQQSGQTIPKAQQTHTGPVLDVDWSDDGTK 91
Query: 204 LASGSSDRTIRFWDLEKFQVV 224
+ + S D+T + WDL Q +
Sbjct: 90 VFTASCDKTAKVWDLNSNQCM 28
>10162
Length = 1629
Score = 40.8 bits (94), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 37/171 (21%), Positives = 73/171 (42%), Gaps = 12/171 (7%)
Frame = +3
Query: 69 VRLNTPEELIVAGSQSGSIRVWDLEAAKILRTL--------MGHKANICSLDFHPYGEFV 120
V + LI++G + +V+++ + K+ ++ S+ F P +
Sbjct: 387 VDCSADNALIMSGCADATAKVFNVSSGKLXSAFNCAASQDSQDKDNSVESVAFCPVSPYA 566
Query: 121 ASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGK 180
A+ + ++++WD+ ++ H + V L++S L +A D +++WD +G
Sbjct: 567 ATATNSGSVQVWDLPTSVARHSFQ-HPEGVCKLQWSSSTALLYTACLDGVMRVWDARSGA 743
Query: 181 MMSEFPGHTGPVNVVEFH--PNEYLLASGSSDRTIRFW--DLEKFQVVSCI 227
+ GH +++F + L SGS D T R DL VS I
Sbjct: 744 SKAVLTGHARNSCILDFDVTRDGTCLVSGSEDGTARVLT*DLHSRNFVSVI 896
Score = 38.9 bits (89), Expect = 0.007, Method: Compositional matrix adjust.
Identities = 21/76 (27%), Positives = 36/76 (47%), Gaps = 2/76 (2%)
Frame = +3
Query: 106 ANICSLDFHPYGEFVASGSQDTNIKLWDI--RRKGCVFRYRGHSQAVRCLRFSPDGKWLA 163
++I L +H + +G+Q + LW + + + + H Q C + P+GK++
Sbjct: 30 SDITWLQWHGGAHVLLAGTQGGEVWLWQVPSQDYSKMKMLQSHGQPSLCGKILPNGKYVC 209
Query: 164 SAADDHTVKLWDLTAG 179
D VKLWDL G
Sbjct: 210 VGYSDGVVKLWDLKTG 257
Score = 35.8 bits (81), Expect = 0.058, Method: Compositional matrix adjust.
Identities = 21/72 (29%), Positives = 32/72 (44%), Gaps = 2/72 (2%)
Frame = +3
Query: 62 HTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPY--GEF 119
H V ++ ++ L+ G +RVWD + L GH N C LDF G
Sbjct: 639 HPEGVCKLQWSSSTALLYTACLDGVMRVWDARSGASKAVLTGHARNSCILDFDVTRDGTC 818
Query: 120 VASGSQDTNIKL 131
+ SGS+D ++
Sbjct: 819 LVSGSEDGTARV 854
>15745
Length = 1183
Score = 40.8 bits (94), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 22/54 (40%), Positives = 32/54 (59%), Gaps = 2/54 (3%)
Frame = +2
Query: 124 SQDTNIKLWDIRRKGCVFRYRG-HSQAVRCLRFSPDGKW-LASAADDHTVKLWD 175
+ + I+ WD+R K ++ G H Q VR L F+P+ ++ LAS DD VK WD
Sbjct: 638 ANEATIRGWDLRSKQQTYQMEGAHGQLVRDLDFNPNRQYYLASCGDDCRVKFWD 799
Score = 38.9 bits (89), Expect = 0.007, Method: Compositional matrix adjust.
Identities = 31/116 (26%), Positives = 56/116 (48%), Gaps = 11/116 (9%)
Frame = +2
Query: 113 FHPYGEF-VASGSQDTNIKLWDIR------RKGCVFRYRGHSQA-VRCLRFSPDGKWLAS 164
+HP G+ G + + +WD+ ++ + G Q + C R++P
Sbjct: 452 WHPTGDSQTVLGVCEDRVIMWDLNVASSSAQQTDMITLEGKGQPRLTCGRWNPHHNCAQI 631
Query: 165 A-ADDHTVKLWDLTAGKMMSEFPG-HTGPVNVVEFHPN-EYLLASGSSDRTIRFWD 217
A A++ T++ WDL + + + G H V ++F+PN +Y LAS D ++FWD
Sbjct: 632 ATANEATIRGWDLRSKQQTYQMEGAHGQLVRDLDFNPNRQYYLASCGDDCRVKFWD 799
Score = 38.1 bits (87), Expect = 0.011, Method: Compositional matrix adjust.
Identities = 22/64 (34%), Positives = 32/64 (50%), Gaps = 1/64 (1%)
Frame = +2
Query: 208 SSDRTIRFWDLEKFQVVSCIEGEPGP-VRSVLFNPDGCCLYSGCQDSLRVYGWEPERCFD 266
+++ TIR WDL Q +EG G VR + FNP+ + C D RV W+ C +
Sbjct: 638 ANEATIRGWDLRSKQQTYQMEGAHGQLVRDLDFNPNRQYYLASCGDDCRVKFWDTRNCSE 817
Query: 267 VVLV 270
+ V
Sbjct: 818 PLKV 829
>14500
Length = 1238
Score = 40.4 bits (93), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 22/45 (48%), Positives = 28/45 (62%)
Frame = +2
Query: 145 GHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHT 189
GHSQ V LR+SPDGK+LAS A+D+ + +W S P HT
Sbjct: 53 GHSQEVCGLRWSPDGKYLASGANDNLLCVWPAQVTGGNSTQPLHT 187
Score = 35.8 bits (81), Expect = 0.049, Method: Compositional matrix adjust.
Identities = 26/97 (26%), Positives = 45/97 (46%), Gaps = 2/97 (2%)
Frame = +3
Query: 80 AGSQSGSIRVWDLEAAKILRTLMGHKANICSLDF-HPYGEFVAS-GSQDTNIKLWDIRRK 137
G+ I W+ L ++ K+ +C+L + + E ++S G + +W
Sbjct: 261 GGTADRHIHFWNCNTGTNLSSV-DTKSQVCALLWSKEHRELISSHGFAQNQLIIWKYPAM 437
Query: 138 GCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLW 174
V GH+ V + SPDG+ + SAA D T++LW
Sbjct: 438 SRVAELTGHTARVLHMAMSPDGETVVSAAADETLRLW 548
Score = 30.8 bits (68), Expect(2) = 0.13, Method: Compositional matrix adjust.
Identities = 24/96 (25%), Positives = 43/96 (44%), Gaps = 2/96 (2%)
Frame = +3
Query: 123 GSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAAD--DHTVKLWDLTAGK 180
G+ D +I W+ + SQ V L +S + + L S+ + + +W A
Sbjct: 264 GTADRHIHFWNCNTGTNLSSVDTKSQ-VCALLWSKEHRELISSHGFAQNQLIIWKYPAMS 440
Query: 181 MMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFW 216
++E GHT V + P+ + S ++D T+R W
Sbjct: 441 RVAELTGHTARVLHMAMSPDGETVVSAAADETLRLW 548
Score = 22.3 bits (46), Expect(2) = 0.13, Method: Compositional matrix adjust.
Identities = 13/61 (21%), Positives = 30/61 (49%), Gaps = 5/61 (8%)
Frame = +2
Query: 56 IMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLE-----AAKILRTLMGHKANICS 110
+ +L+GH+ V +R + + + +G+ + VW + + + L T H+A + +
Sbjct: 38 VGTLSGHSQEVCGLRWSPDGKYLASGANDNLLCVWPAQVTGGNSTQPLHTFSQHQAAVKA 217
Query: 111 L 111
L
Sbjct: 218 L 220
Score = 34.3 bits (77), Expect = 0.16, Method: Compositional matrix adjust.
Identities = 18/59 (30%), Positives = 30/59 (50%), Gaps = 5/59 (8%)
Frame = +2
Query: 100 TLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGC-----VFRYRGHSQAVRCL 153
TL GH +C L + P G+++ASG+ D + +W + G + + H AV+ L
Sbjct: 44 TLSGHSQEVCGLRWSPDGKYLASGANDNLLCVWPAQVTGGNSTQPLHTFSQHQAAVKAL 220
>10264
Length = 416
Score = 40.4 bits (93), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 31/107 (28%), Positives = 52/107 (48%), Gaps = 6/107 (5%)
Frame = -1
Query: 116 YGEFVAS---GSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSP--DGKWLASAADDHT 170
+GE A+ G ++T + L +R GHSQ V + +SP D + L S D
Sbjct: 329 FGEMGATEREGDKETLLILTSLRE------LSGHSQRVTDMSWSPHHDAR-LVSVGYDAE 171
Query: 171 VKLWDLTAGKMMSEFPGHTGPVNVVEFHP-NEYLLASGSSDRTIRFW 216
+WD+ G +++F GH G + +F + L+ +G SD ++ W
Sbjct: 170 AFVWDVQKGTALAQFKGHMGRLLTCQFSGLDPDLVMTGGSDASVHVW 30
Score = 32.0 bits (71), Expect = 0.91, Method: Compositional matrix adjust.
Identities = 16/79 (20%), Positives = 34/79 (43%), Gaps = 1/79 (1%)
Frame = -1
Query: 13 LQEIVAHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLN 72
L+E+ H+ V+ + L + G D +W + K + GH + + + +
Sbjct: 266 LRELSGHSQRVTDMSWSPHHDARLVSVGYDAEAFVWDVQKGTALAQFKGHMGRLLTCQFS 87
Query: 73 TPE-ELIVAGSQSGSIRVW 90
+ +L++ G S+ VW
Sbjct: 86 GLDPDLVMTGGSDASVHVW 30
>31474
Length = 403
Score = 40.0 bits (92), Expect = 0.003, Method: Composition-based stats.
Identities = 25/98 (25%), Positives = 44/98 (44%), Gaps = 5/98 (5%)
Frame = -3
Query: 145 GHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFP---GHTGPVNVVEFHPNE 201
H + C+ ++P G LAS D +K+W + + HT V + + P
Sbjct: 311 AHDEHAWCVAWNPTGTLLASCGSDKIIKIWGKEGDNWVCKSTLTDAHTRTVRSLGWSPCG 132
Query: 202 YLLASGSSDRTIRFWDLE--KFQVVSCIEGEPGPVRSV 237
L+S S D T W + +F+ ++ +EG V++V
Sbjct: 131 NYLSSASFDATTAVWSRKGGEFECIATLEGHENEVKAV 18
>17298
Length = 476
Score = 40.0 bits (92), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 15/43 (34%), Positives = 27/43 (62%)
Frame = -1
Query: 175 DLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWD 217
++ +G+ + ++ H G VN V+F+ ++ SGS D T+R WD
Sbjct: 254 NVASGQALRKYRDHAGTVNCVKFNEESTVILSGSLDNTVRAWD 126
Score = 35.8 bits (81), Expect = 0.060, Method: Compositional matrix adjust.
Identities = 18/75 (24%), Positives = 37/75 (49%)
Frame = -1
Query: 142 RYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNE 201
+YR H+ V C++F+ + + S + D+TV+ WD + +V ++
Sbjct: 227 KYRDHAGTVNCVKFNEESTVILSGSLDNTVRAWDTRSRSHTPIQVLDEATDSVTSIQVSD 48
Query: 202 YLLASGSSDRTIRFW 216
Y + +GS+D +R +
Sbjct: 47 YEILTGSADGRVRRY 3
>15972
Length = 1069
Score = 40.0 bits (92), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 21/71 (29%), Positives = 33/71 (46%)
Frame = +3
Query: 99 RTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPD 158
RT GHK + L HP G+ + SQD ++LW+ G + +A +R++P
Sbjct: 219 RTFSGHKGPVRHLAVHPSGKLTLTVSQDRTLRLWN-NMNGRIAFISNMKEAAESVRWAPG 395
Query: 159 GKWLASAADDH 169
G + A H
Sbjct: 396 GLYYVVAFRSH 428
Score = 39.7 bits (91), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 24/78 (30%), Positives = 35/78 (44%)
Frame = +3
Query: 185 FPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVLFNPDGC 244
F GH GPV + HP+ L + S DRT+R W+ + ++ I SV + P G
Sbjct: 225 FSGHKGPVRHLAVHPSGKLTLTVSQDRTLRLWNNMNGR-IAFISNMKEAAESVRWAPGGL 401
Query: 245 CLYSGCQDSLRVYGWEPE 262
+ L VY E +
Sbjct: 402 YYVVAFRSHLDVYSVESK 455
Score = 32.0 bits (71), Expect = 0.77, Method: Compositional matrix adjust.
Identities = 13/39 (33%), Positives = 21/39 (53%)
Frame = +3
Query: 143 YRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKM 181
+ GH VR L P GK + + D T++LW+ G++
Sbjct: 225 FSGHKGPVRHLAVHPSGKLTLTVSQDRTLRLWNNMNGRI 341
>31118
Length = 390
Score = 39.7 bits (91), Expect = 0.004, Method: Composition-based stats.
Identities = 20/64 (31%), Positives = 33/64 (51%), Gaps = 5/64 (7%)
Frame = -2
Query: 146 HSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPG-----HTGPVNVVEFHPN 200
HS +RC+RFSP ++ + + D T+KL DL G + ++ H + +HP
Sbjct: 383 HSAEIRCIRFSPSAYYMLTCSYDSTIKLTDLQ-GDLANDIASVVVAKHKDKAITIRWHPT 207
Query: 201 EYLL 204
E+ L
Sbjct: 206 EFPL 195
>25400
Length = 462
Score = 39.7 bits (91), Expect = 0.004, Method: Composition-based stats.
Identities = 17/57 (29%), Positives = 33/57 (57%), Gaps = 1/57 (1%)
Frame = +3
Query: 78 IVAGSQSGSIRVWDLEAAKILRTL-MGHKANICSLDFHPYGEFVASGSQDTNIKLWD 133
+ +G +G+I ++DL +++R L GH++ + + +HPY + S S D + WD
Sbjct: 6 VYSGCATGTILIYDLLTGRVVRKLDGGHRSCVRDVSWHPYTNTLISSSWDGTVGKWD 176
Score = 33.1 bits (74), Expect = 0.36, Method: Composition-based stats.
Identities = 22/70 (31%), Positives = 35/70 (50%), Gaps = 1/70 (1%)
Frame = +3
Query: 170 TVKLWDLTAGKMMSEFPG-HTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIE 228
T+ ++DL G+++ + G H V V +HP L S S D T+ WD + +
Sbjct: 30 TILIYDLLTGRVVRKLDGGHRSCVRDVSWHPYTNTLISSSWDGTVGKWDYFDYWAH---D 200
Query: 229 GEPGPVRSVL 238
GE G V+ V+
Sbjct: 201 GEEGEVKMVV 230
>16436
Length = 1316
Score = 39.3 bits (90), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 27/102 (26%), Positives = 50/102 (49%), Gaps = 4/102 (3%)
Frame = +3
Query: 77 LIVAGSQSGSIRVWDL-EAAKILRTLMGHKANICSLDFHPYGEFVASGSQD-TNIKLWDI 134
L G + G +++ DL + K + H+AN+C + + G +A+ S+ T I+++D
Sbjct: 138 LAFPGRKLGHVQIVDLADTEKAAMDIAAHEANLCCMAMNMGGSRLATASEKGTLIRVFDA 317
Query: 135 RRKGCVFRYR--GHSQAVRCLRFSPDGKWLASAADDHTVKLW 174
+ R +S + C+ FS D L A+D TV ++
Sbjct: 318 VSGAQLHELRRGANSANIYCINFSADSTLLCVASDHGTVHIF 443
>02948
Length = 1207
Score = 38.5 bits (88), Expect = 0.010, Method: Compositional matrix adjust.
Identities = 28/118 (23%), Positives = 48/118 (40%), Gaps = 2/118 (1%)
Frame = -2
Query: 114 HPYGEFVASGSQDTNIKLW-DIRRKGCVFRY-RGHSQAVRCLRFSPDGKWLASAADDHTV 171
HP +A+G I W + + V HS V CL F+P+G L S + T+
Sbjct: 729 HPTDVCIATGHASGKITFWWNFDQDKTVLSVSHWHSLPVTCLAFTPEGSCLLSGGHECTL 550
Query: 172 KLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEG 229
W + + + P P++ + P+ +G SD ++ F ++ I G
Sbjct: 549 VRWQMNS-EHKEFLPRLGAPLHNIVVSPDGVFFVTGHSDNVLQVIT-SSFSIMXAIRG 382
Score = 35.4 bits (80), Expect = 0.072, Method: Compositional matrix adjust.
Identities = 21/58 (36%), Positives = 29/58 (50%), Gaps = 3/58 (5%)
Frame = -2
Query: 195 VEFHPNEYLLASGSSDRTIRFW---DLEKFQVVSCIEGEPGPVRSVLFNPDGCCLYSG 249
V HP + +A+G + I FW D +K V+S PV + F P+G CL SG
Sbjct: 738 VSCHPTDVCIATGHASGKITFWWNFDQDK-TVLSVSHWHSLPVTCLAFTPEGSCLLSG 568
>06799
Length = 616
Score = 37.4 bits (85), Expect = 0.019, Method: Compositional matrix adjust.
Identities = 38/161 (23%), Positives = 69/161 (42%), Gaps = 15/161 (9%)
Frame = +3
Query: 33 GRLLATGGDDCRVNLWSI--NKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVW 90
G L+ DD ++LW+ KP + SL + L + + G++ G++ +
Sbjct: 21 GALVTVCADDT-LHLWNYRQKKPEIVHSLKFQRERITYCHLPFQSKWLYIGTERGNVHIV 197
Query: 91 DLEAAKILRTLMG-HKANICSLDFHPYGEFVA------------SGSQDTNIKLWDIRRK 137
++E+ + ++ +KA S HP G V G + I LWD+R K
Sbjct: 198 NIESFILSGYIINWNKAIELSRKTHP-GPVVHLSDNPVDSNKLLIGFESGAIVLWDLRSK 374
Query: 138 GCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTA 178
RY +A+R + + +GK + D ++ W+L A
Sbjct: 375 AAECRYNS-PEALRSIAWHFEGKQFMCSHSDGSLTTWNLKA 494
>37142
Length = 327
Score = 37.4 bits (85), Expect = 0.020, Method: Compositional matrix adjust.
Identities = 20/67 (29%), Positives = 38/67 (56%), Gaps = 7/67 (10%)
Frame = +2
Query: 77 LIVAGSQSGSIRVW------DLEAAKILRTLMGHKANICSLDFHPY-GEFVASGSQDTNI 129
+IV G+ +GS+ V+ D +A + L H + +LDF+P+ +ASG+ ++ I
Sbjct: 2 VIVGGADNGSVLVYSAQKMIDGDADCSVLQLTKHTGAVKALDFNPFQTNLLASGASESEI 181
Query: 130 KLWDIRR 136
+WD+ +
Sbjct: 182 YIWDLNK 202
Score = 36.6 bits (83), Expect = 0.035, Method: Compositional matrix adjust.
Identities = 20/50 (40%), Positives = 29/50 (58%), Gaps = 1/50 (2%)
Frame = +2
Query: 172 KLWDLTAGKMMSEFPGHTGPVNVVEFHPNEY-LLASGSSDRTIRFWDLEK 220
K+ D A + + HTG V ++F+P + LLASG+S+ I WDL K
Sbjct: 53 KMIDGDADCSVLQLTKHTGAVKALDFNPFQTNLLASGASESEIYIWDLNK 202
Score = 32.0 bits (71), Expect = 0.72, Method: Compositional matrix adjust.
Identities = 20/79 (25%), Positives = 35/79 (44%), Gaps = 3/79 (3%)
Frame = +2
Query: 15 EIVAHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRL--- 71
++ H V +L LLA+G + + +W +NKP+ M+ + P E V
Sbjct: 89 QLTKHTGAVKALDFNPFQTNLLASGASESEIYIWDLNKPDNPMTPGQKSQPPEEVSCVAW 268
Query: 72 NTPEELIVAGSQSGSIRVW 90
N + I+A + + VW
Sbjct: 269 NRQVQHILASNFAARCVVW 325
>05642
Length = 445
Score = 37.0 bits (84), Expect = 0.022, Method: Composition-based stats.
Identities = 20/58 (34%), Positives = 33/58 (56%), Gaps = 1/58 (1%)
Frame = -1
Query: 203 LLASGSSDRTIRFWDLEKFQVVSCIEGEPG-PVRSVLFNPDGCCLYSGCQDSLRVYGW 259
L+ SGS D + FWDL + ++V ++ + PV S+ F+ CL + C D +V+ W
Sbjct: 367 LVVSGSEDGKVYFWDLVEAKLVDTLDHKTTRPVHSLSFHHAELCLMTACAD--KVFLW 200
>20662
Length = 1220
Score = 37.0 bits (84), Expect = 0.023, Method: Compositional matrix adjust.
Identities = 34/140 (24%), Positives = 57/140 (40%), Gaps = 7/140 (5%)
Frame = +2
Query: 36 LATGGDDCRVNLWSINKPNCIMSLTG----HTSPVESVRLNTPEELIVAGSQSGSIRVWD 91
L TGG V LW + + + S+ H SV +N+ ++ S I+VW+
Sbjct: 305 LDTGG----VALWELQDEDKMFSMLSSACEHDDMTASVSINSDXSHYLSASYDHGIKVWN 472
Query: 92 LEAAKILRTLMGHKANICSLDFHPYG-EFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAV 150
+ L T H + + HP S SQD I LWD+R S
Sbjct: 473 TDLTS-LYTYRAHSDIVWDVQCHPTEPALFLSCSQDGKIVLWDVRESKPATCLPKCSSGF 649
Query: 151 R--CLRFSPDGKWLASAADD 168
+ C+++ P+ + + + D+
Sbjct: 650 KPTCVQWQPNARNMYAVGDE 709
>38177
Length = 430
Score = 36.6 bits (83), Expect = 0.029, Method: Compositional matrix adjust.
Identities = 25/95 (26%), Positives = 42/95 (44%), Gaps = 6/95 (6%)
Frame = +3
Query: 111 LDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRY----RGHSQAVRCLRFSPDGKWLASAA 166
L + P G + +G+ LW+ G F + + H +VR +R+S +W+ +A
Sbjct: 6 LAWTPEGRRLVTGASSGEFTLWN----GLTFNFETILQAHDVSVRAMRWSNHDQWMVTAD 173
Query: 167 DDHTVKLW--DLTAGKMMSEFPGHTGPVNVVEFHP 199
+K W ++ KM F GH P+ V P
Sbjct: 174 HSGYIKYWQSNMNNVKM---FQGHKEPIRGVRLAP 269
Score = 35.0 bits (79), Expect = 0.099, Method: Compositional matrix adjust.
Identities = 19/92 (20%), Positives = 36/92 (39%)
Frame = +3
Query: 152 CLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDR 211
CL ++P+G+ L + A LW+ + H V + + ++ + +
Sbjct: 3 CLAWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDVSVRAMRWSNHDQWMVTADHSG 182
Query: 212 TIRFWDLEKFQVVSCIEGEPGPVRSVLFNPDG 243
I++W V +G P+R V P G
Sbjct: 183 YIKYWQ-SNMNNVKMFQGHKEPIRGVRLAPPG 275
>04395
Length = 1145
Score = 36.6 bits (83), Expect = 0.037, Method: Compositional matrix adjust.
Identities = 34/126 (26%), Positives = 58/126 (46%), Gaps = 16/126 (12%)
Frame = +3
Query: 28 LGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPV------ESVRLNT----PEEL 77
L S +L +GG+D R+ L S GH +PV +S +N +
Sbjct: 231 LASYSXDVLMSGGEDGRLALLS----------PGHATPVRLMEKADSCTINALTFLKQSQ 380
Query: 78 IVAGSQSGSIRVWDL-----EAAKILRTLMGHKANICSLDFHPYG-EFVASGSQDTNIKL 131
++ + G ++++D+ E A+I H + +C +D HP VA+GSQD + +
Sbjct: 381 VLTVNSFGQLKLFDVRQNSDEPAQIFSATDDHWSLLC-VDKHPGQLHIVATGSQDGTLTV 557
Query: 132 WDIRRK 137
WD+R
Sbjct: 558 WDLRHH 575
>39204
Length = 1684
Score = 35.8 bits (81), Expect = 0.049, Method: Compositional matrix adjust.
Identities = 19/38 (50%), Positives = 20/38 (52%), Gaps = 6/38 (15%)
Frame = -2
Query: 146 HSQAVRCLRFSP------DGKWLASAADDHTVKLWDLT 177
H +AVRCLRF P L SA DD KLW LT
Sbjct: 1272 HYKAVRCLRFKPVTDSESPAPMLVSAGDDGMFKLWTLT 1159
>07665
Length = 435
Score = 35.0 bits (79), Expect = 0.099, Method: Compositional matrix adjust.
Identities = 32/99 (32%), Positives = 48/99 (48%), Gaps = 11/99 (11%)
Frame = -2
Query: 90 WDLEAAKILRTLMGHKANICSLDFHP--YGEFVASGSQDTNIKLWDIRRKGCVFRYR--- 144
WDL K L TL H I +L F P Y VA G +IK+WD+ K V R
Sbjct: 392 WDLNDGKNLYTLE-HNDIINALCFSPNRYWLCVAYGP---SIKIWDLACKKTVEELRPEV 225
Query: 145 ----GHSQAVRCLR--FSPDGKWLASAADDHTVKLWDLT 177
++ +CL +S DG+ L + D+T+++W ++
Sbjct: 224 VSPTSKAEQPQCLSLAWSTDGQTLFAGYSDNTIRVWQVS 108
>13890
Length = 630
Score = 34.7 bits (78), Expect = 0.13, Method: Compositional matrix adjust.
Identities = 25/82 (30%), Positives = 39/82 (47%), Gaps = 11/82 (13%)
Frame = +1
Query: 113 FHPYG-EFVASGSQDTNIKLWDIRRKGCVFRYRGHSQ---AVRCLRFSPDGKWLASAAD- 167
FHP VA+G+ D I++WD+R R H + V+ + FS DG+ + S D
Sbjct: 4 FHPVTPHLVATGTTDC-IQVWDVRHPEVPVRVLTHKEQLGQVQDVMFSHDGQEVFSCGDV 180
Query: 168 ------DHTVKLWDLTAGKMMS 183
D ++ WD G ++S
Sbjct: 181 VSRESSDRSIMAWDFRTGVILS 246
>05303
Length = 782
Score = 34.3 bits (77), Expect = 0.15, Method: Compositional matrix adjust.
Identities = 29/115 (25%), Positives = 48/115 (41%), Gaps = 16/115 (13%)
Frame = -3
Query: 39 GGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPE------------ELIVAGSQSGS 86
GG D V+LW++NK ++ +T S + + E +L+ GS+ G
Sbjct: 648 GGQDNSVSLWNVNKKKALVCVTSAHSGCSQIEGSKGENWITAVASLQFTDLVATGSKDGC 469
Query: 87 IRVWDLEAAKILRTLMGH---KANICSLDFHPYGEFVASG-SQDTNIKLWDIRRK 137
IR+W A + + SL F G+F+ +G Q+ + W RK
Sbjct: 468 IRLWQCSANFHHLVPLXSVPVPGFVNSLKFSSKGDFLLAGVGQEHRLGRWWSLRK 304
>35695
Length = 1651
Score = 34.3 bits (77), Expect = 0.15, Method: Compositional matrix adjust.
Identities = 24/98 (24%), Positives = 48/98 (48%), Gaps = 2/98 (2%)
Frame = -1
Query: 18 AHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKP-NCIMSLTGHTSPVESVRLNTPEE 76
AH + +L ++ + D +N+W+ +K + L P+E+V +
Sbjct: 1591 AHFGRIIALTSVTVGCNMVISSSIDKTINVWNFDKILEEVHPLDRMERPIETVHMAASSS 1412
Query: 77 LIVAGSQSGSIRVWDLEAAKILRTLMG-HKANICSLDF 113
L VA +++ + VWDLE ++++ L+G ++N S F
Sbjct: 1411 LCVATTRNQT-SVWDLETGRLVKVLVGSSRSNXVSQAF 1301
>04524
Length = 1340
Score = 33.9 bits (76), Expect = 0.21, Method: Compositional matrix adjust.
Identities = 32/165 (19%), Positives = 70/165 (42%), Gaps = 16/165 (9%)
Frame = -1
Query: 33 GRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPV-----ESVRLNTPEELIVAGSQSGSI 87
GR LA D ++++++ + P+ S +S + SV + E ++ ++G +
Sbjct: 1289 GRYLAVCDDXKKLHVFTRDAPHTPQSWALISSRLLARRATSVTFTSDEGQVIVADKTGDV 1110
Query: 88 RVW----------DLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRK 137
+ + E + L+GH + + + V + +D I++
Sbjct: 1109 YTFPTTTQVEVKDEGEVKTHGQLLLGHLSMVLDVCLTGREGHVVTCDRDEKIRVSQFPNA 930
Query: 138 GCVFRY-RGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKM 181
+ Y GH+Q V CL + + + L S + D TV+ W++ ++
Sbjct: 929 YNIHTYCLGHTQFVNCLVYVEEFRVLISGSGDCTVRAWNMEGKQL 795
Score = 31.2 bits (69), Expect = 1.5, Method: Compositional matrix adjust.
Identities = 18/52 (34%), Positives = 27/52 (51%), Gaps = 10/52 (19%)
Frame = -1
Query: 182 MSEFP----------GHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQV 223
+S+FP GHT VN + + +L SGS D T+R W++E Q+
Sbjct: 950 VSQFPNAYNIHTYCLGHTQFVNCLVYVEEFRVLISGSGDCTVRAWNMEGKQL 795
>36111
Length = 687
Score = 33.5 bits (75), Expect = 0.25, Method: Compositional matrix adjust.
Identities = 18/56 (32%), Positives = 25/56 (44%)
Frame = +2
Query: 191 PVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVLFNPDGCCL 246
PVN V FH A+G SD + WD + + P + S+ F+ DG L
Sbjct: 236 PVNAVAFHNVYNTFATGGSDGYVNIWDGFHKKRLCXFHRYPTSIASLAFSHDGNVL 403
>25880
Length = 423
Score = 33.5 bits (75), Expect = 0.27, Method: Composition-based stats.
Identities = 22/71 (30%), Positives = 31/71 (43%)
Frame = +2
Query: 62 HTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVA 121
H V+SV + E IV GS +RV++LE L G + A
Sbjct: 53 HKHIVKSVAFDNSSENIVTGSNEKLVRVFNLEQPDAEPELYGGHTGAIKRALY------A 214
Query: 122 SGSQDTNIKLW 132
SGS+D ++LW
Sbjct: 215 SGSEDGTLRLW 247
Score = 33.5 bits (75), Expect = 0.31, Method: Composition-based stats.
Identities = 21/88 (23%), Positives = 41/88 (46%), Gaps = 1/88 (1%)
Frame = +2
Query: 130 KLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSE-FPGH 188
K+W+ + ++ H V+ + F + + + +++ V++++L E + GH
Sbjct: 8 KVWNAVSGAEIHSFQ-HKHIVKSVAFDNSSENIVTGSNEKLVRVFNLEQPDAEPELYGGH 184
Query: 189 TGPVNVVEFHPNEYLLASGSSDRTIRFW 216
TG + L ASGS D T+R W
Sbjct: 185 TGAIK-------RALYASGSEDGTLRLW 247
>30108
Length = 1032
Score = 33.1 bits (74), Expect = 0.40, Method: Compositional matrix adjust.
Identities = 31/110 (28%), Positives = 43/110 (39%), Gaps = 12/110 (10%)
Frame = +1
Query: 108 ICSLDFHPYGEFVASGSQ-DTNIKLWDIRRKGC-VFRYRGHSQAVRCLRFSPDGKWLASA 165
I L + P + S S DT + W + + C RY G V L SPDG + +A
Sbjct: 388 ITHLAWLPSANILLSASPVDTAVMAWSVGGEACTALRYLG-GGGVSLLACSPDGSKVMAA 564
Query: 166 ADDHTVKLWDLT----------AGKMMSEFPGHTGPVNVVEFHPNEYLLA 205
++WD T +G+ S H G V V +E L A
Sbjct: 565 TPATLFRVWDTTSWHCEVWSQLSGRCTSACWSHDGQVXVFSMEGDEALHA 714
>27681
Length = 465
Score = 32.7 bits (73), Expect = 0.44, Method: Compositional matrix adjust.
Identities = 25/98 (25%), Positives = 49/98 (50%), Gaps = 14/98 (14%)
Frame = +2
Query: 108 ICSLDFHPYGEFVASGSQDTNIKLWDIRRKG------CVFRY---RGHSQA-----VRCL 153
IC+ ++P + +ASGS D+ ++W++ + V R+ +G ++ V L
Sbjct: 8 ICA--WNPTNDLLASGSGDSTARIWNMTSETPNNANQLVLRHCIQKGGTEVPSNKDVTSL 181
Query: 154 RFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGP 191
++ +G LA+ + D +LW T G +++ H GP
Sbjct: 182 DWNSEGTLLATGSYDGYARLW-RTDGHLVNTLGQHKGP 292
Score = 31.6 bits (70), Expect = 1.0, Method: Compositional matrix adjust.
Identities = 19/75 (25%), Positives = 36/75 (48%), Gaps = 14/75 (18%)
Frame = +2
Query: 72 NTPEELIVAGSQSGSIRVWDLEAAK-------ILR-------TLMGHKANICSLDFHPYG 117
N +L+ +GS + R+W++ + +LR T + ++ SLD++ G
Sbjct: 20 NPTNDLLASGSGDSTARIWNMTSETPNNANQLVLRHCIQKGGTEVPSNKDVTSLDWNSEG 199
Query: 118 EFVASGSQDTNIKLW 132
+A+GS D +LW
Sbjct: 200 TLLATGSYDGYARLW 244
Score = 30.4 bits (67), Expect = 2.1, Method: Compositional matrix adjust.
Identities = 23/75 (30%), Positives = 35/75 (46%), Gaps = 14/75 (18%)
Frame = +2
Query: 192 VNVVEFHPNEYLLASGSSDRTIRFWDL--------EKFQVVSCIE--GEPGP----VRSV 237
V + ++P LLASGS D T R W++ + + CI+ G P V S+
Sbjct: 2 VFICAWNPTNDLLASGSGDSTARIWNMTSETPNNANQLVLRHCIQKGGTEVPSNKDVTSL 181
Query: 238 LFNPDGCCLYSGCQD 252
+N +G L +G D
Sbjct: 182 DWNSEGTLLATGSYD 226
>13486
Length = 1509
Score = 32.7 bits (73), Expect = 0.52, Method: Compositional matrix adjust.
Identities = 13/43 (30%), Positives = 22/43 (51%)
Frame = -1
Query: 54 NCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAK 96
+C+ L GH++PV V N E L+ + G + +W E +
Sbjct: 927 SCVNKLLGHSAPVLDVCFNCDESLLASCDAQGMVIIWKREGKQ 799
>30297
Length = 822
Score = 32.3 bits (72), Expect = 0.54, Method: Compositional matrix adjust.
Identities = 20/67 (29%), Positives = 31/67 (46%), Gaps = 10/67 (14%)
Frame = -1
Query: 129 IKLWDIRRK----------GCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTA 178
I +WDI + + +RGH ++V CL K L ++A D TV++W T
Sbjct: 312 IYVWDISQYCLETPETDSPDVIQSWRGHVESVSCLDLVEQNKVLLTSAADCTVRMW-TTD 136
Query: 179 GKMMSEF 185
G + F
Sbjct: 135 GHYIGTF 115
>27475
Length = 369
Score = 32.3 bits (72), Expect = 0.65, Method: Compositional matrix adjust.
Identities = 15/34 (44%), Positives = 20/34 (58%), Gaps = 1/34 (2%)
Frame = +2
Query: 185 FPGHTGPVNVVEFHPN-EYLLASGSSDRTIRFWD 217
F HTG V V++ P E+L SGS D ++ WD
Sbjct: 56 FTSHTGWVTGVDWSPTREHLFLSGSYDNVLKLWD 157
Score = 29.6 bits (65), Expect = 4.2, Method: Compositional matrix adjust.
Identities = 18/68 (26%), Positives = 28/68 (41%), Gaps = 2/68 (2%)
Frame = +2
Query: 91 DLEAAKILRTLMGHKANICSLDFHPYGE-FVASGSQDTNIKLWDIRR-KGCVFRYRGHSQ 148
D E + H + +D+ P E SGS D +KLWD R K ++ H
Sbjct: 26 DTEGETVKCAFTSHTGWVTGVDWSPTREHLFLSGSYDNVLKLWDTRSPKATLYDMNWHED 205
Query: 149 AVRCLRFS 156
+ + +S
Sbjct: 206 RILAVDWS 229
>07781
Length = 1269
Score = 32.0 bits (71), Expect = 0.83, Method: Compositional matrix adjust.
Identities = 17/62 (27%), Positives = 33/62 (53%), Gaps = 4/62 (6%)
Frame = -2
Query: 78 IVAGSQSGSIRVWDLEAAKILRT----LMGHKANICSLDFHPYGEFVASGSQDTNIKLWD 133
++ +G++ V+++E+ + T +A IC+ D E + SGS D +K+WD
Sbjct: 881 VITSDSAGNLTVFEVESTTVRETSQWRAHDFEAWICAFD-QWNTELIYSGSDDCKLKVWD 705
Query: 134 IR 135
+R
Sbjct: 704 LR 699
Score = 32.0 bits (71), Expect = 0.83, Method: Compositional matrix adjust.
Identities = 26/103 (25%), Positives = 46/103 (44%), Gaps = 3/103 (2%)
Frame = -2
Query: 142 RYRGHS-QAVRCLRFSPDGKWLASAADDHTVKLWDLTAGK--MMSEFPGHTGPVNVVEFH 198
++R H +A C + + + S +DD +K+WDL G +++ G ++
Sbjct: 809 QWRAHDFEAWICAFDQWNTELIYSGSDDCKLKVWDLRVGTTPVLTNSRFTMGVTSIQSCP 630
Query: 199 PNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVLFNP 241
E+LLA GS D +R +D + G V V ++P
Sbjct: 629 QREHLLAVGSYDENLRLFDTRHMRQPLSTTALEGGVWRVKWDP 501
Score = 31.6 bits (70), Expect = 1.1, Method: Compositional matrix adjust.
Identities = 23/67 (34%), Positives = 32/67 (47%), Gaps = 6/67 (8%)
Frame = -2
Query: 76 ELIVAGSQSGSIRVWDLEAAKI-----LRTLMGHKANICSLDFHPYGE-FVASGSQDTNI 129
ELI +GS ++VWDL R MG + S+ P E +A GS D N+
Sbjct: 752 ELIYSGSDDCKLKVWDLRVGTTPVLTNSRFTMG----VTSIQSCPQREHLLAVGSYDENL 585
Query: 130 KLWDIRR 136
+L+D R
Sbjct: 584 RLFDTRH 564
>22113
Length = 614
Score = 30.8 bits (68), Expect = 1.6, Method: Compositional matrix adjust.
Identities = 17/78 (21%), Positives = 33/78 (42%)
Frame = +3
Query: 141 FRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPN 200
++ H V LRF+ GKW S D+ + W G + + T V + +
Sbjct: 84 YQLHLHESCVLSLRFATCGKWFVSTGKDNLLNAWRTPYGASIFQ-SKETSSVLSCDISTD 260
Query: 201 EYLLASGSSDRTIRFWDL 218
+ + +GS D+ +++
Sbjct: 261 DKYIVTGSGDKKATVYEV 314
>12372
Length = 1287
Score = 30.8 bits (68), Expect = 1.6, Method: Compositional matrix adjust.
Identities = 16/43 (37%), Positives = 23/43 (53%)
Frame = +3
Query: 479 QAELVDEDAMSQIRKGHDTMCVVLTSRHKNLDTVRAVWTMGDI 521
+E +D++A Q R+ H + V + S KNL A W MG I
Sbjct: 252 HSEFLDKEACKQTRQEH--LPVHVASNDKNLSERGAAWNMGHI 374
>30176
Length = 365
Score = 30.8 bits (68), Expect = 1.8, Method: Composition-based stats.
Identities = 13/31 (41%), Positives = 18/31 (58%)
Frame = +2
Query: 144 RGHSQAVRCLRFSPDGKWLASAADDHTVKLW 174
+ H+ V L F G LAS +DD T+K+W
Sbjct: 11 KSHTSTVWNLTFDKTGTRLASCSDDKTIKIW 103
>20271
Length = 567
Score = 30.8 bits (68), Expect = 1.8, Method: Compositional matrix adjust.
Identities = 16/70 (22%), Positives = 31/70 (44%), Gaps = 6/70 (8%)
Frame = -1
Query: 185 FPGHTGPVNVVEFHPNEY------LLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVL 238
+ GH GP+ ++ H + S D T++ W++++ + V E V V
Sbjct: 297 YEGHQGPITAIDTHHAAGQIDFSPFFLTASFDWTVKLWNIKEQKYVCSFEDNSDYVSDVQ 118
Query: 239 FNPDGCCLYS 248
++P L+S
Sbjct: 117 WSPTNPALFS 88
>13509
Length = 572
Score = 30.4 bits (67), Expect = 2.4, Method: Compositional matrix adjust.
Identities = 16/52 (30%), Positives = 23/52 (44%)
Frame = +2
Query: 192 VNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVLFNPDG 243
VN + FHP L++ SD FWD + + E P+ + FN G
Sbjct: 368 VNDISFHPVHGTLSTVGSDGRFSFWDKDARTKLKTSEQFDQPITTCNFNAQG 523
>31054
Length = 392
Score = 30.0 bits (66), Expect = 3.0, Method: Compositional matrix adjust.
Identities = 19/71 (26%), Positives = 30/71 (42%)
Frame = -2
Query: 147 SQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLAS 206
S+AV SPD VK W G + GH +N + + ++ +L S
Sbjct: 382 SKAVHFAXGSPD-----------XVKQWKFPDGNFIQNLSGHNAIINTLAVN-SDGVLVS 239
Query: 207 GSSDRTIRFWD 217
G+ + T+ WD
Sbjct: 238 GADNGTMHLWD 206
>25930
Length = 419
Score = 29.3 bits (64), Expect = 4.7, Method: Compositional matrix adjust.
Identities = 20/90 (22%), Positives = 42/90 (46%)
Frame = +1
Query: 26 LVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSG 85
+ +G G +L D R+ W + + I G ++++ + +++ S+SG
Sbjct: 103 VAVGSVRGDILIY---DVRLEPWRLAR---IAPSNGQDDSIKNLNWSLDATRLISVSESG 264
Query: 86 SIRVWDLEAAKILRTLMGHKANICSLDFHP 115
+++VWDLE + +K + L+ HP
Sbjct: 265 TLQVWDLEGPAV------NKQDARLLELHP 336
>30727
Length = 402
Score = 29.3 bits (64), Expect = 5.9, Method: Compositional matrix adjust.
Identities = 20/65 (30%), Positives = 28/65 (43%), Gaps = 5/65 (7%)
Frame = +1
Query: 38 TGGDDCRVNLWSINKPNCI-----MSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDL 92
+GG D R+ W +KP C+ L TS + +N P +A + GSI L
Sbjct: 115 SGGMDSRLVHWDFSKPKCLNQFNMQELHSTTSDASAYMINPPFIHHLAKNSDGSIIACAL 294
Query: 93 EAAKI 97
E I
Sbjct: 295 ENGLI 309
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000320130 | hsapiens_gene_ensembl | Cytoplasmic
dynein 1 intermediate chain 1 (Dynein intermediate chain 1, cytosolic)
(DH IC-1) (Cytoplasmic dynein intermediate chain 1).
[Source:Uniprot/SWISSPROT;Acc:O14576]
(645 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
20271 283 2e-76
14105 168 7e-42
12841 120 1e-27
07741 57 3e-08
20662 49 5e-06
08355 49 9e-06
03387 45 8e-05
13278 40 0.003
01598 39 0.010
02960 36 0.054
15972 35 0.086
13335 35 0.11
27475 33 0.30
01768 32 0.63
05393 32 0.77
27465 32 1.2
00561 29 6.8
37180 28 8.3
>20271
Length = 567
Score = 283 bits (723), Expect = 2e-76, Method: Compositional matrix adjust.
Identities = 130/188 (69%), Positives = 154/188 (81%)
Frame = -1
Query: 390 HPVYCVNVVGTQNAHNLITVSTDGKMCSWSLDMLSTPQESMELVYNKSKPVAVTGMAFPT 449
HPVYC+ VVGTQNAHNLI+VS DGK+CSWSLDMLS PQ+SMEL + +SK VA T +F +
Sbjct: 567 HPVYCITVVGTQNAHNLISVSNDGKLCSWSLDMLSQPQDSMELQHKQSKSVAATCFSFLS 388
Query: 450 GDVNNFVVGSEEGTVYTACRHGSKAGIGEVFEGHQGPVTGINCHMAVGPIDFSHLFVTSS 509
GD NNF+VGSEE VY+A RHGSKAGI E +EGHQGP+T I+ H A G IDFS F+T+S
Sbjct: 387 GDANNFIVGSEECLVYSASRHGSKAGINEAYEGHQGPITAIDTHHAAGQIDFSPFFLTAS 208
Query: 510 FDWTVKLWTTKHNKPLYSFEDNADYVYDVMWSPVHPALFACVDGMGRLDLWNLNNDTEVP 569
FDWTVKLW K K + SFEDN+DYV DV WSP +PALF+CVD MGRLDLW+LN++TEVP
Sbjct: 207 FDWTVKLWNIKEQKYVCSFEDNSDYVSDVQWSPTNPALFSCVDIMGRLDLWHLNHETEVP 28
Query: 570 TASVAIEG 577
TASV ++G
Sbjct: 27 TASVVVDG 4
>14105
Length = 429
Score = 168 bits (425), Expect = 7e-42, Method: Compositional matrix adjust.
Identities = 78/120 (65%), Positives = 93/120 (77%), Gaps = 1/120 (0%)
Frame = +3
Query: 516 LWTTKHNKPLYSFEDNADYVYDVMWSPVHPALFACVDGMGRLDLWNLNNDTEVPTASVAI 575
LW+ K KPLYSFEDN+DYV DV WSPVHPALFA VDG GRLDLWNLN DTEVPTAS+ +
Sbjct: 3 LWSLKDTKPLYSFEDNSDYVMDVAWSPVHPALFAAVDGSGRLDLWNLNQDTEVPTASIVV 182
Query: 576 EGASALNRVRWAQAGKEVAVGDSEGRIWVYDVGE-LAVPHNDEWTRFARTLVEIRANRAD 634
+GA ALNRV W +G V +GD G+++VYDV E LA+P DEW+RF TL E++ N+ D
Sbjct: 183 DGAPALNRVSWTPSGLHVTIGDESGKLYVYDVAEHLALPTRDEWSRFNATLNELKMNQND 362
Score = 29.6 bits (65), Expect = 3.6, Method: Compositional matrix adjust.
Identities = 18/61 (29%), Positives = 24/61 (39%), Gaps = 1/61 (1%)
Frame = +3
Query: 327 KFKKTTPEYVFHCQSS-VMSVCFARFHPNLVVGGTYSGQIVLWDNRSHRRTPVQRTPLSA 385
K T P Y F S VM V ++ HP L SG++ LW+ P +
Sbjct: 9 SLKDTKPLYSFEDNSDYVMDVAWSPVHPALFAAVDGSGRLDLWNLNQDTEVPTASIVVDG 188
Query: 386 A 386
A
Sbjct: 189 A 191
>12841
Length = 1364
Score = 120 bits (302), Expect = 1e-27, Method: Compositional matrix adjust.
Identities = 84/329 (25%), Positives = 148/329 (44%), Gaps = 25/329 (7%)
Frame = +1
Query: 285 SKHRVVTCMDWSLQYPELMVASYNNNEDAPHEPDGVALVWNMKFKKTTPEYVFHCQSSVM 344
+K R V+C+ W+ P+L+ Y D ++ G+ W++K PE V+ V
Sbjct: 394 TKGRNVSCLAWNKSNPDLVAVGYGQF-DFTNQKSGLICCWSLK-NPEYPERVYTSTHGVT 567
Query: 345 SVCFARFHPNLVVGGTYSGQIVLWDNRSHRRTPVQRTPLSAAAHTHPVYCVNVV------ 398
S+ F+ + N++ G Y G + +++ RS P+ + H PV+ + +
Sbjct: 568 SLDFSVANANILAAGYYDGGVAIYNVRSTSDEPILDNQETHGKHLGPVWQIQWIEKERGS 747
Query: 399 GTQNAHNLITVSTDGKMCSWSLDMLSTPQESMELVYNKSKPVAVTGMA------------ 446
G + A LI++STDG++ WS+ ES ++ K P + G A
Sbjct: 748 GEERAEVLISISTDGRVTQWSI---RKGFESNNIMRLKKLPTRMAGKAREKKGEAFISRH 918
Query: 447 -------FPTGDVNNFVVGSEEGTVYTACRHGSKAGIGEVFEGHQGPVTGINCHMAVGPI 499
F + D+N ++ G+EEG ++ C E + GH PV H+ P
Sbjct: 919 AGGLCFDFHSRDLNVYLAGTEEGYIH-KCSCSYNEQYLETYSGHTAPVY----HIRWSPF 1083
Query: 500 DFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMWSPVHPALFACVDGMGRLDL 559
S +F++ S DW+++LW P+ +F + V+DV WSP +FACV G +++
Sbjct: 1084-VSDIFLSCSADWSIRLWHQDRTTPILTFHSSTKTVHDVCWSPRSSTVFACVH-EGAVEV 1257
Query: 560 WNLNNDTEVPTASVAIEGASALNRVRWAQ 588
W+L T ++ + L V + +
Sbjct: 1258WDLAQSTLDAVITITPTSGAKLTSVTFGK 1344
>07741
Length = 2119
Score = 56.6 bits (135), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 44/165 (26%), Positives = 77/165 (46%), Gaps = 17/165 (10%)
Frame = +1
Query: 455 FVVGSEEGTVYTACRHGSKAGIGEVFEGHQGPVTGINCHMAVGPIDFSH----LFVTSSF 510
F+VG+EEG V+ C + + + H +MAV + ++H ++ T S
Sbjct: 157 FLVGTEEGKVH-VCSKAYTSHFIDTLDSH---------NMAVYKVAWNHYHPKIYATCSA 306
Query: 511 DWTVKLWT-----------TKHNKPLYSFEDNADYVYDVMWSPVHPALFACVDGMGRLDL 559
DW VK+W + KPL+SF+ N + V DV W+P +FA V G++ +
Sbjct: 307 DWNVKIWENGGKPTDTGXDSLSRKPLFSFDLN-NSVGDVAWAPYSSTVFAAVTADGKVCV 483
Query: 560 WNLNNDTEVPTAS--VAIEGASALNRVRWAQAGKEVAVGDSEGRI 602
++L+ + P VA + + L + + + + VGD G +
Sbjct: 484 YDLSVNKYEPLCEQMVAQKKKTKLTHIEFNPSYPILIVGDDRGNV 618
>20662
Length = 1220
Score = 49.3 bits (116), Expect = 5e-06, Method: Compositional matrix adjust.
Identities = 37/133 (27%), Positives = 64/133 (48%), Gaps = 4/133 (3%)
Frame = +2
Query: 500 DFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMWSPVHPALFACVDGMGRLDL 559
D SH ++++S+D +K+W T LY++ ++D V+DV P PALF G++ L
Sbjct: 419 DXSH-YLSASYDHGIKVWNTDLTS-LYTYRAHSDIVWDVQCHPTEPALFLSCSQDGKIVL 592
Query: 560 WNLNND---TEVPTASVAIEGASALNRVRWAQAGKEV-AVGDSEGRIWVYDVGELAVPHN 615
W++ T +P S + V+W + + AVGD G + V D+ + V N
Sbjct: 593 WDVRESKPATCLPKCSSGFKPTC----VQWQPNARNMYAVGDEGGHVSVQDL-RMVVEKN 757
Query: 616 DEWTRFARTLVEI 628
+ R + +
Sbjct: 758 VSYQSHNRVVTRL 796
>08355
Length = 498
Score = 48.5 bits (114), Expect = 9e-06, Method: Composition-based stats.
Identities = 43/175 (24%), Positives = 73/175 (41%), Gaps = 18/175 (10%)
Frame = -1
Query: 361 YSGQIVLWDNRSHRRTPVQRTPLSAAAHTHPVYCV--NVVGTQNAHNLITVSTDGKMCSW 418
Y G + L++ PVQR HT PV+ V + N N ++S+DG++ W
Sbjct: 495 YDGSVALFNTIEKHNNPVQRCTADNGKHTDPVWQVRWQKDDSDNNMNFFSISSDGRIVHW 316
Query: 419 S----------LDMLSTPQESMELVYNKSKPVAVTGMAFPTGDVNN--FVVGSEEGTVYT 466
+ + L+ P E V G AF + F+VG+EEG ++
Sbjct: 315 TIVKNEMIYQDIIQLTIPGPPAEGPDGIRMEVTGCGTAFDFHKHKDYLFLVGTEEGKMHV 136
Query: 467 ACRHGSKAGIGEVFEGHQGPVTGINCHMAVGPIDFS----HLFVTSSFDWTVKLW 517
+ + IG +G +MA+ + ++ +++ T S DW VK+W
Sbjct: 135 CSKAYTSHFIG----------SGDAHNMAIYKVAWNRFHPNVYATCSADWNVKIW 1
>03387
Length = 1891
Score = 45.1 bits (105), Expect = 8e-05, Method: Compositional matrix adjust.
Identities = 56/221 (25%), Positives = 95/221 (42%), Gaps = 10/221 (4%)
Frame = +1
Query: 353 PNLVVGGTYSGQIVLWDNRSHRRTP---VQRTP-LSAAAHTHPVYCVNVVGTQNAHNLIT 408
P ++ T S ++++D H P + P L H Y ++ N H L++
Sbjct: 241 PCIIATKTPSSDVLVFDYTKHPSKPDPSGECIPELRLKGHQKEGYGLSWNPNLNGH-LLS 417
Query: 409 VSTDGKMCSWSLDMLSTPQES----MELVYNKSKPVAVTGMAFPTGDVNNF-VVGSEEGT 463
S D +C W D+ ST +ES ++ V V +A+ + F V ++
Sbjct: 418 ASDDHTICLW--DINSTQRESRVVDAHTIFTGHTSV-VEDVAWHLLHESLFGSVADDQKL 588
Query: 464 VYTACRHGSKAGIGEVFEGHQGPVTGINCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNK 523
+ R + + V + H V NC ++ P + T S D TV LW ++ K
Sbjct: 589 MIWDTRSNTTSKPSHVVDAHTAEV---NC-LSFNPYS-EFILATGSADKTVALWDLRNLK 753
Query: 524 -PLYSFEDNADYVYDVMWSPVHPALFACVDGMGRLDLWNLN 563
L+SFE + D ++ V WSP + + A RL +W+L+
Sbjct: 754 LKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLHVWDLS 876
>13278
Length = 870
Score = 39.7 bits (91), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 29/110 (26%), Positives = 51/110 (46%), Gaps = 4/110 (3%)
Frame = +1
Query: 502 SHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMWSPVHPALFACVDGMGRLD--- 558
S + ++SFD TV+LW + L++ + + VY V +SP L + G D
Sbjct: 112 SLILASASFDSTVRLWEVERGLCLHTLTKHQEPVYSVAFSPDGKYLAS-----GSFDKCV 276
Query: 559 -LWNLNNDTEVPTASVAIEGASALNRVRWAQAGKEVAVGDSEGRIWVYDV 607
+WN+ + V + +G + V W G +V S+G ++V D+
Sbjct: 277 HIWNVQTGSLVH----SYKGTGGIFEVCWNHRGDKVGASASDGSVFVLDL 414
>01598
Length = 1545
Score = 38.5 bits (88), Expect = 0.010, Method: Compositional matrix adjust.
Identities = 40/137 (29%), Positives = 57/137 (41%), Gaps = 3/137 (2%)
Frame = +1
Query: 480 FEGHQGPVTGINCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVM 539
+ H PV I A GP S T + D V LW + + + S +VY V
Sbjct: 364 YRPHMRPVFNI---CASGPD--SKTLCTFAQDRQVVLWDLETMEAVASMATLGGHVYCVR 528
Query: 540 WSPVHPALFACVDGMGRLDLWNLNNDTEVPTASVAIEG-ASALNRVRWAQAGKE--VAVG 596
SP+ P A G + WN++N T + +G S + V W KE + G
Sbjct: 529 TSPIDPGRVAVGVGDSMIRTWNMSNKTNPYDVTTLWQGIKSKVTAVAW-HPTKEGWLGFG 705
Query: 597 DSEGRIWVYDVGELAVP 613
+GRI V+DV +P
Sbjct: 706 TDDGRIGVFDVLSHKMP 756
>02960
Length = 1577
Score = 35.8 bits (81), Expect = 0.054, Method: Compositional matrix adjust.
Identities = 57/257 (22%), Positives = 95/257 (36%), Gaps = 33/257 (12%)
Frame = +2
Query: 318 DGVALVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPN--LVVGGTYSGQIVLWDNRSH-- 373
D ALVW + + + C+ SV P+ + G++ + LW +
Sbjct: 680 DQTALVWQWQRETNEVDCRLSCRGHAASVDCVAVSPDSQQMCTGSWDKMLKLWSTDCNVD 859
Query: 374 -----------------RRTPVQRTP-LSAAAHTHPVYCVNVVGTQNAHNLITVSTDGKM 415
+ T R P L+ + H V V + + H ++T S D +
Sbjct: 860 GDQSEDTERPSKKKKSAKSTTQTRVPVLTLSGHAEAVSAVRWL---DPHRVVTSSWDHSL 1030
Query: 416 CSWSL------DMLSTPQESMELVYNKSKPVAVTGMAFPTGDVNNFVVGSEEGTVYTACR 469
W L ++ + +++ Y+ + +TG A D + +V C
Sbjct: 1031RLWDLHTAQQTSLIQGSKAVLDVAYSPLSHMLITGSA----DRHVRLVDPR-------CS 1177
Query: 470 HGSKAGIGEVFEGHQGPVTGINCHMAVGPIDFS----HLFVTSSFDWTVKLWTTKHNKP- 524
G F H G VTG+ D+S HLF++ S+D +KLW T+ K
Sbjct: 1178EGETVKCA--FTSHTGWVTGV---------DWSPTREHLFLSGSYDNVLKLWDTRSPKAT 1324
Query: 525 LYSFEDNADYVYDVMWS 541
LY + D + V WS
Sbjct: 1325LYDMNWHEDRILAVDWS 1375
>15972
Length = 1069
Score = 35.0 bits (79), Expect = 0.086, Method: Compositional matrix adjust.
Identities = 24/83 (28%), Positives = 40/83 (48%)
Frame = +3
Query: 480 FEGHQGPVTGINCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVM 539
F GH+GPV H+AV P L +T S D T++LW + + + + + V
Sbjct: 225 FSGHKGPVR----HLAVHP--SGKLTLTVSQDRTLRLWNNMNGRIAF-ISNMKEAAESVR 383
Query: 540 WSPVHPALFACVDGMGRLDLWNL 562
W+P L+ V LD++++
Sbjct: 384 WAP--GGLYYVVAFRSHLDVYSV 446
>13335
Length = 863
Score = 34.7 bits (78), Expect = 0.11, Method: Compositional matrix adjust.
Identities = 55/234 (23%), Positives = 86/234 (36%), Gaps = 26/234 (11%)
Frame = +1
Query: 322 LVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNL--VVGGTYSGQIVLWDNRSHRRTPVQ 379
+VW++K EY H S + VC +F P+ +V G+ I +W+ Q
Sbjct: 7 IVWDVKTGSIKGEYQ-HASKSSIRVC--KFSPSSSHLVSGSDDDTICMWE------VATQ 159
Query: 380 RTPLSAAAHTHPVYCVNVVGTQNAHNLITVSTDGKMCSWSLDM-------LSTPQESMEL 432
+ S H V + + + N H L++ S +G + W L + +
Sbjct: 160 KLVRSYVGHEDSV--MALAYSPNGHYLVSGSPNGDLYVWDASFGHCRHLTLRVDAHDLGV 333
Query: 433 VYNKSKPVAVTGMA---------FPTGDVNNFV--------VGSEEGTVYTACRHGSKAG 475
+ P T A TG +N + VGS E T+ CR
Sbjct: 334 TCCEFSPTFGTACAENSSTCNLLLATGGKDNLIKLWTFSAQVGSPEVTL--QCR------ 489
Query: 476 IGEVFEGHQGPVTGINCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFE 529
++ GH V MA S L + SFD +V+LW + L+S E
Sbjct: 490 --DILSGHSDLV------MACAFSPSSALLASGSFDKSVRLWDSVKGVALFSIE 627
>27475
Length = 369
Score = 33.5 bits (75), Expect = 0.30, Method: Compositional matrix adjust.
Identities = 25/75 (33%), Positives = 34/75 (45%), Gaps = 1/75 (1%)
Frame = +2
Query: 479 VFEGHQGPVTGINCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKP-LYSFEDNADYVYD 537
F H G VTG++ HLF++ S+D +KLW T+ K LY + D +
Sbjct: 53 AFTSHTGWVTGVDWSPTR-----EHLFLSGSYDNVLKLWDTRSPKATLYDMNWHEDRILA 217
Query: 538 VMWSPVHPALFACVD 552
V WS L VD
Sbjct: 218 VDWSIPELLLSGGVD 262
>01768
Length = 1424
Score = 32.3 bits (72), Expect = 0.63, Method: Compositional matrix adjust.
Identities = 29/120 (24%), Positives = 53/120 (44%), Gaps = 17/120 (14%)
Frame = +3
Query: 461 EGTVYTAC------------RHGSKAGIGEVFEGHQGPVTGINCHMAVGPIDFSHLFVTS 508
EG V+ +C + SKA + V E H + IN + PI+ HL +
Sbjct: 873 EGNVFASCSVDRTLRIWNTQQKPSKANVLTVPEAHSRDINVINWN----PIE-KHLLASG 1037
Query: 509 SFDWTVKLWTTK--HNKPL---YSFEDNADYVYDVMWSPVHPALFACVDGMGRLDLWNLN 563
D +K+W + NKP+ SF+ ++ V + W+P ++ A ++ +W+ +
Sbjct: 1038GDDGIIKIWDLRMFRNKPVSAQASFKLHSQPVTSLEWNPQDSSVLAASGEDDQITIWDFS 1217
Score = 30.8 bits (68), Expect = 1.5, Method: Compositional matrix adjust.
Identities = 26/93 (27%), Positives = 39/93 (41%), Gaps = 2/93 (2%)
Frame = +3
Query: 517 WTTKHNKPLYSFEDNADYVYDVMWSPVHPALFACVDGMGRLDLWNLNNDTEVPTASVAIE 576
WTT+ + S+ + D V DV WSP +FA L +WN E
Sbjct: 804 WTTEKS----SYAAHTDSVEDVQWSPNEGNVFASCSVDRTLRIWNTQQKPSKANVLTVPE 971
Query: 577 GASA-LNRVRWAQAGKE-VAVGDSEGRIWVYDV 607
S +N + W K +A G +G I ++D+
Sbjct: 972 AHSRDINVINWNPIEKHLLASGGDDGIIKIWDL 1070
>05393
Length = 904
Score = 32.0 bits (71), Expect = 0.77, Method: Compositional matrix adjust.
Identities = 24/93 (25%), Positives = 41/93 (44%), Gaps = 7/93 (7%)
Frame = +1
Query: 483 HQGPVTGINCHMA-VGPIDFSH----LFVTSSFDWTVKLWTTKHNKPLYSFEDNADY--V 535
H+ PV + H + V + S L +T+S D T+K+W + +KP + F N +
Sbjct: 187 HEKPVFSVGAHSSCVTGVCLSSQIPGLMITTSEDKTMKVWDIQDDKPTHVFSRNLKMKEL 366
Query: 536 YDVMWSPVHPALFACVDGMGRLDLWNLNNDTEV 568
+ P P +FA G +W++ V
Sbjct: 367 HCTGCCPEAPFVFAVGGGRREPKVWDIRESAAV 465
>27465
Length = 658
Score = 31.6 bits (70), Expect = 1.2, Method: Compositional matrix adjust.
Identities = 29/103 (28%), Positives = 47/103 (45%), Gaps = 2/103 (1%)
Frame = -1
Query: 442 VTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIGEV--FEGHQGPVTGINCHMAVGPI 499
+T +AF ++F+ GS + T C+ A E+ EGH+ V I + P
Sbjct: 352 LTNVAFNKSG-SSFITGSYDRT----CKIWDTASAEELHTLEGHRNVVYAIAFN---NP- 200
Query: 500 DFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMWSP 542
F +T SFD T KLW+T K ++ + + V ++P
Sbjct: 199 -FGDKVITGSFDKTCKLWSTADGKCYHTLRGHTAEIVCVSFNP 74
>00561
Length = 1003
Score = 28.9 bits (63), Expect = 6.8, Method: Compositional matrix adjust.
Identities = 30/89 (33%), Positives = 42/89 (47%), Gaps = 4/89 (4%)
Frame = -3
Query: 480 FEGHQGPVTGINCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFED-NADYVYDV 538
FEGH V ++V + V+ S D T+KLW T ED + D+V V
Sbjct: 752 FEGHTKDV------LSVAFSADNRQIVSGSRDKTIKLWNTLAECKFTIQEDGHTDWVSCV 591
Query: 539 MWSPVH--PALFACVDGMGR-LDLWNLNN 564
+SP H P + +C G R + +WNL N
Sbjct: 590 RFSPNHSNPIIVSC--GWDRTVKVWNLAN 510
>37180
Length = 681
Score = 28.5 bits (62), Expect = 8.3, Method: Compositional matrix adjust.
Identities = 31/112 (27%), Positives = 49/112 (43%), Gaps = 6/112 (5%)
Frame = +1
Query: 478 EVFEGHQGPVTGINCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYD 537
V GH ++ ++ H L VTSS D T +LW + + L + V+
Sbjct: 1 NVLNGHDQELSDVHAHPT------QRLVVTSSKDMTFRLWDFRDSALLVN-------VFQ 141
Query: 538 VMWSPVHPALFACVDGM--GRLD----LWNLNNDTEVPTASVAIEGASALNR 583
PV A+FA D + G D +W++ N P A++ + SA+NR
Sbjct: 142 GHTQPVTSAVFASGDKVVSGSDDRTVRVWDMRN-MRSPIATIRTD--SAVNR 288
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000368982 | hsapiens_gene_ensembl | Katanin p80
WD40-containing subunit B1 (Katanin p80 subunit B1) (p80 katanin).
[Source:Uniprot/SWISSPROT;Acc:Q9BVA0]
(655 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
19949 282 2e-76
30256 113 2e-25
00561 100 2e-21
17598 97 1e-20
12806 92 5e-19
13335 90 3e-18
17602 85 9e-17
02147 82 1e-15
03156 80 2e-15
01327 80 3e-15
27465 79 4e-15
29912 78 1e-14
12574 75 8e-14
19498 67 2e-11
02960 65 7e-11
01805 65 1e-10
03395 65 1e-10
12960 64 1e-10
13278 64 1e-10
16199 54 1e-10
03387 64 2e-10
04088 63 3e-10
17266 63 5e-10
01768 60 3e-09
14555 44 5e-09
11493 59 6e-09
02090 59 6e-09
27270 57 2e-08
15118 56 4e-08
01462 55 6e-08
18981 55 7e-08
15780 55 1e-07
01249 55 1e-07
21105 54 2e-07
26939 54 2e-07
37180 52 1e-06
31864 50 4e-06
19863 50 4e-06
00825 49 6e-06
15337 49 9e-06
27806 49 9e-06
26107 47 2e-05
21921 47 2e-05
11915 47 2e-05
19140 46 4e-05
34005 46 4e-05
01598 46 5e-05
30295 45 7e-05
21960 43 3e-04
04358 42 7e-04
21763 42 9e-04
16105 42 9e-04
31384 41 0.002
10162 41 0.002
15745 41 0.002
14500 40 0.002
10264 40 0.002
31474 40 0.003
17298 40 0.003
15972 40 0.003
31118 40 0.004
25400 40 0.004
16436 39 0.005
02948 39 0.010
06799 37 0.019
37142 37 0.020
05642 37 0.022
20662 37 0.023
38177 37 0.029
04395 37 0.037
39204 36 0.049
07665 35 0.099
13890 35 0.13
05303 34 0.15
35695 34 0.15
04524 34 0.21
36111 33 0.25
25880 33 0.27
30108 33 0.40
27681 33 0.44
13486 33 0.52
30297 32 0.54
27475 32 0.65
07781 32 0.83
22113 31 1.6
12372 31 1.6
30176 31 1.8
20271 31 1.8
13509 30 2.4
31054 30 3.0
25930 29 4.7
30727 29 5.9
>19949
Length = 903
Score = 282 bits (722), Expect = 2e-76, Method: Compositional matrix adjust.
Identities = 136/284 (47%), Positives = 187/284 (65%), Gaps = 4/284 (1%)
Frame = +2
Query: 108 ICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAAD 167
+ SLDFHPYG + ASGS D N+KLWDIRRKGC++ Y+GH+ V CLRFSPDG+W+ASA++
Sbjct: 2 VKSLDFHPYGAYTASGSMDCNVKLWDIRRKGCIYTYKGHTGCVCCLRFSPDGRWIASASE 181
Query: 168 DHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCI 227
D VKLWDLTAGK++++ H VN +EFHP+E+LLASGS+DRT++FWDLE FQ++S
Sbjct: 182 DGLVKLWDLTAGKLLTDLKLHRDAVNTIEFHPHEFLLASGSADRTVKFWDLETFQLISTT 361
Query: 228 EGEPGPVRSVLFNPDGCCLYSGCQDSLRVYGWEPERCFDVVLVNWGKVADLAICNDQLIG 287
E E +RS+LF+PDG CLYSG +D+L+VY WEP +D V V WG+V D++I N QLIG
Sbjct: 362 EPEANSIRSILFHPDGVCLYSGSKDTLKVYHWEPLELYDTVSVPWGQVCDMSISNTQLIG 541
Query: 288 VAFSQSNVSSYVVDLTRVTRTGTVARDPVQDHRPLAQPLPNPSAPLRRIYERPST----T 343
+F ++NV+SYVVD+ +V+ G +++ R + L N I +RP T
Sbjct: 542 ASFYKTNVASYVVDIEKVSHIGKPTPSSLENRRE-STSLSNNRRSF--ITDRPPTQSTQQ 712
Query: 344 CSKPQRVKQNXXXXXXXXXXXXXXXXXXXXAEIQNAEDYNEIFQ 387
S P+R A+I+N +Y E+F+
Sbjct: 713 TSDPKRSDD--------PGEKSDDVEESSGADIRNPAEYRELFK 820
Score = 97.4 bits (241), Expect = 2e-20, Method: Compositional matrix adjust.
Identities = 48/142 (33%), Positives = 77/142 (54%)
Frame = +2
Query: 33 GRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDL 92
G A+G DC V LW I + CI + GHT V +R + I + S+ G +++WDL
Sbjct: 29 GAYTASGSMDCNVKLWDIRRKGCIYTYKGHTGCVCCLRFSPDGRWIASASEDGLVKLWDL 208
Query: 93 EAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRC 152
A K+L L H+ + +++FHP+ +ASGS D +K WD+ + + ++R
Sbjct: 209 TAGKLLTDLKLHRDAVNTIEFHPHEFLLASGSADRTVKFWDLETFQLISTTEPEANSIRS 388
Query: 153 LRFSPDGKWLASAADDHTVKLW 174
+ F PDG L S + D T+K++
Sbjct: 389 ILFHPDGVCLYSGSKD-TLKVY 451
>30256
Length = 961
Score = 113 bits (283), Expect = 2e-25, Method: Compositional matrix adjust.
Identities = 63/221 (28%), Positives = 120/221 (54%)
Frame = +3
Query: 13 LQEIVAHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLN 72
++ ++ H V S + +G + +G D + +W+ + C +L GH+S V + L+
Sbjct: 21 IKNLIGHTGGVWS---SQMTGNTVISGSTDRSLKVWNADTGVCTHTLYGHSSTVRCLSLS 191
Query: 73 TPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLW 132
+ +V+GS+ ++RVWD+E+ L L+GH A + + + G+ V SG+ D +++W
Sbjct: 192 GKK--VVSGSRDATLRVWDIESGHCLNVLLGHMAAVRCVQYD--GKRVVSGAXDYTVRVW 359
Query: 133 DIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPV 192
D C+ +GH+ V L+F DG ++ S + D ++++WD+ GK++ GH
Sbjct: 360 DPDTASCLHTLQGHTNRVYSLQF--DGVYVVSGSLDTSIRVWDVRCGKLVHTLMGHQSLT 533
Query: 193 NVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGP 233
+ +E N LL SG++D T++ WD+ + C++ GP
Sbjct: 534 SGLELKDN--LLVSGNADSTVKVWDVHTGK---CLQTLLGP 641
Score = 107 bits (266), Expect = 2e-23, Method: Compositional matrix adjust.
Identities = 68/209 (32%), Positives = 103/209 (49%), Gaps = 3/209 (1%)
Frame = +3
Query: 14 QEIVAHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNT 73
+ H+S V L L SG+ + +G D + +W I +C+ L GH + V V+ +
Sbjct: 144 HTLYGHSSTVRCLSL---SGKKVVSGSRDATLRVWDIESGHCLNVLLGHMAAVRCVQYDG 314
Query: 74 PEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWD 133
+V+G+ ++RVWD + A L TL GH + SL F G +V SGS DT+I++WD
Sbjct: 315 KR--VVSGAXDYTVRVWDPDTASCLHTLQGHTNRVYSLQFD--GVYVVSGSLDTSIRVWD 482
Query: 134 IRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPG---HTG 190
+R V GH L + L S D TVK+WD+ GK + G H
Sbjct: 483 VRCGKLVHTLMGHQSLTSGLELKDN--LLVSGNADSTVKVWDVHTGKCLQTLLGPNKHRS 656
Query: 191 PVNVVEFHPNEYLLASGSSDRTIRFWDLE 219
V ++F N+ + + S D T++ WDL
Sbjct: 657 AVTCLQF--NKKFVVTCSDDGTVKLWDLN 737
Score = 104 bits (259), Expect = 1e-22, Method: Compositional matrix adjust.
Identities = 67/216 (31%), Positives = 109/216 (50%), Gaps = 1/216 (0%)
Frame = +3
Query: 55 CIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFH 114
CI +L GHT V S ++ +++GS S++VW+ + TL GH + + L
Sbjct: 18 CIKNLIGHTGGVWSSQM--TGNTVISGSTDRSLKVWNADTGVCTHTLYGHSSTVRCLSLS 191
Query: 115 PYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLW 174
G+ V SGS+D +++WDI C+ GH AVRC+++ DGK + S A D+TV++W
Sbjct: 192 --GKKVVSGSRDATLRVWDIESGHCLNVLLGHMAAVRCVQY--DGKRVVSGAXDYTVRVW 359
Query: 175 DLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGPV 234
D + GHT V ++F + + SGS D +IR WD+ ++V + G
Sbjct: 360 DPDTASCLHTLQGHTNRVYSLQF--DGVYVVSGSLDTSIRVWDVRCGKLVHTLMGHQSLT 533
Query: 235 RSVLFNPDGCCLYSGCQDS-LRVYGWEPERCFDVVL 269
+ + L SG DS ++V+ +C +L
Sbjct: 534 SGLELKDN--LLVSGNADSTVKVWDVHTGKCLQTLL 635
Score = 97.8 bits (242), Expect = 1e-20, Method: Compositional matrix adjust.
Identities = 63/208 (30%), Positives = 107/208 (51%), Gaps = 8/208 (3%)
Frame = +3
Query: 13 LQEIVAHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLN 72
L ++ H + V + + G+ + +G D V +W + +C+ +L GHT+ V S++ +
Sbjct: 261 LNVLLGHMAAVRCV---QYDGKRVVSGAXDYTVRVWDPDTASCLHTLQGHTNRVYSLQFD 431
Query: 73 TPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLW 132
+V+GS SIRVWD+ K++ TLMGH++ L+ + SG+ D+ +K+W
Sbjct: 432 GV--YVVSGSLDTSIRVWDVRCGKLVHTLMGHQSLTSGLELKD--NLLVSGNADSTVKVW 599
Query: 133 DIRRKGCVFRYRG---HSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEF---- 185
D+ C+ G H AV CL+F+ K++ + +DD TVKLWDL G +
Sbjct: 600 DVHTGKCLQTLLGPNKHRSAVTCLQFNK--KFVVTCSDDGTVKLWDLNTGDFIRNLITLP 773
Query: 186 -PGHTGPVNVVEFHPNEYLLASGSSDRT 212
G G V + + + + A GS + T
Sbjct: 774 SGGSGGVVWRLRCNNTKMVCAVGSRNGT 857
>00561
Length = 1003
Score = 100 bits (250), Expect = 2e-21, Method: Compositional matrix adjust.
Identities = 62/203 (30%), Positives = 101/203 (49%), Gaps = 4/203 (1%)
Frame = -3
Query: 59 LTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGE 118
L GH+ + V L++ ++GS ++R+WDL A K R GH ++ S+ F
Sbjct: 878 LYGHSHFISDVVLSSDGNYALSGSWDQTLRLWDLAAGKTTRRFEGHTKDVLSVAFSADNR 699
Query: 119 FVASGSQDTNIKLWDIRRKGCVFRYR--GHSQAVRCLRFSPD--GKWLASAADDHTVKLW 174
+ SGS+D IKLW+ + C F + GH+ V C+RFSP+ + S D TVK+W
Sbjct: 698 QIVSGSRDKTIKLWNTLAE-CKFTIQEDGHTDWVSCVRFSPNHSNPIIVSCGWDRTVKVW 522
Query: 175 DLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGPV 234
+L K+ + GH G +N V P+ L SG D WDL + + +E +
Sbjct: 521 NLANCKLKNNHHGHNGYLNTVTVSPDGSLCTSGGKDSKALLWDLNDGKNLYTLEHN-DII 345
Query: 235 RSVLFNPDGCCLYSGCQDSLRVY 257
++ F+P+ L S++++
Sbjct: 344 NALCFSPNRYWLCVAYGPSIKIW 276
Score = 90.1 bits (222), Expect = 2e-18, Method: Compositional matrix adjust.
Identities = 56/187 (29%), Positives = 91/187 (48%), Gaps = 9/187 (4%)
Frame = -3
Query: 76 ELIVAGSQSGSIRVW------DLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNI 129
+ I++ S+ ++ VW D + L GH I + G + SGS D +
Sbjct: 971 DTIISASRDKTLIVWKLTRDEDTNYGYPQKRLYGHSHFISDVVLSSDGNYALSGSWDQTL 792
Query: 130 KLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWD-LTAGKMMSEFPGH 188
+LWD+ R+ GH++ V + FS D + + S + D T+KLW+ L K + GH
Sbjct: 791 RLWDLAAGKTTRRFEGHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTLAECKFTIQEDGH 612
Query: 189 TGPVNVVEFHPNEY--LLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVLFNPDGCCL 246
T V+ V F PN ++ S DRT++ W+L ++ + G G + +V +PDG
Sbjct: 611 TDWVSCVRFSPNHSNPIIVSCGWDRTVKVWNLANCKLKNNHHGHNGYLNTVTVSPDGSLC 432
Query: 247 YSGCQDS 253
SG +DS
Sbjct: 431 TSGGKDS 411
Score = 80.5 bits (197), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 60/217 (27%), Positives = 92/217 (42%), Gaps = 5/217 (2%)
Frame = -3
Query: 7 TKTAWKLQEIVAHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPV 66
T + + + H+ +S +VL + G +G D + LW + GHT V
Sbjct: 905 TNYGYPQKRLYGHSHFISDVVL-SSDGNYALSGSWDQTLRLWDLAAGKTTRRFEGHTKDV 729
Query: 67 ESVRLNTPEELIVAGSQSGSIRVWD-LEAAKILRTLMGHKANICSLDFHP--YGEFVASG 123
SV + IV+GS+ +I++W+ L K GH + + F P + S
Sbjct: 728 LSVAFSADNRQIVSGSRDKTIKLWNTLAECKFTIQEDGHTDWVSCVRFSPNHSNPIIVSC 549
Query: 124 SQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMS 183
D +K+W++ + GH+ + + SPDG S D LWDL GK +
Sbjct: 548 GWDRTVKVWNLANCKLKNNHHGHNGYLNTVTVSPDGSLCTSGGKDSKALLWDLNDGKNLY 369
Query: 184 EFPGHTGPVNVVEFHPNEYLL--ASGSSDRTIRFWDL 218
H +N + F PN Y L A G S I+ WDL
Sbjct: 368 TLE-HNDIINALCFSPNRYWLCVAYGPS---IKIWDL 270
>17598
Length = 875
Score = 97.4 bits (241), Expect = 1e-20, Method: Compositional matrix adjust.
Identities = 54/204 (26%), Positives = 101/204 (49%), Gaps = 4/204 (1%)
Frame = +1
Query: 58 SLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYG 117
+L GH+ V V L+ +++ S ++R+WD++ R + H + ++ F P
Sbjct: 106 TLQGHSHFVSDVSLSADSRYVLSSSWDATLRLWDIKKGNTTRRFISHTRDALAVAFSPDN 285
Query: 118 EFVASGSQDTNIKLWDIRRKGCVFRY--RGHSQAVRCLRFSPDGK--WLASAADDHTVKL 173
+ASG +D +K+W+ + C F H V C++F D K + SA+ D T+K+
Sbjct: 286 RQIASGGRDKALKIWNTVGE-CKFTVDANSHQDWVTCVKFHQDAKSPLVVSASMDKTIKV 462
Query: 174 WDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGP 233
WD + F GH +N ++ Y LASGS D + W+++ + I+ +
Sbjct: 463 WDNQTMTLKHTFVGHKTQINAIDLALKTYYLASGSKDGIVMTWNIQNGTFLGKIDCDC-E 639
Query: 234 VRSVLFNPDGCCLYSGCQDSLRVY 257
V +V F+P+ L+ G + ++++
Sbjct: 640 VNAVKFSPNKYWLFVGTSEGIQIW 711
Score = 78.6 bits (192), Expect = 8e-15, Method: Compositional matrix adjust.
Identities = 52/194 (26%), Positives = 86/194 (44%), Gaps = 14/194 (7%)
Frame = +1
Query: 75 EELIVAGSQSGSIRVWDLEAAKI----------LRTLMGHKANICSLDFHPYGEFVASGS 124
+E ++ G + + VWDL K RTL GH + + +V S S
Sbjct: 1 KEFLIXGGRDKLLIVWDLVPRKDGDEDETWGGPRRTLQGHSHFVSDVSLSADSRYVLSSS 180
Query: 125 QDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAG--KMM 182
D ++LWDI++ R+ H++ + FSPD + +AS D +K+W+ T G K
Sbjct: 181 WDATLRLWDIKKGNTTRRFISHTRDALAVAFSPDNRQIASGGRDKALKIWN-TVGECKFT 357
Query: 183 SEFPGHTGPVNVVEFHPNEY--LLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVLFN 240
+ H V V+FH + L+ S S D+TI+ WD + + G + ++
Sbjct: 358 VDANSHQDWVTCVKFHQDAKSPLVVSASMDKTIKVWDNQTMTLKHTFVGHKTQINAIDLA 537
Query: 241 PDGCCLYSGCQDSL 254
L SG +D +
Sbjct: 538 LKTYYLASGSKDGI 579
Score = 77.8 bits (190), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 55/217 (25%), Positives = 93/217 (42%), Gaps = 3/217 (1%)
Frame = +1
Query: 18 AHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEEL 77
H+ VS + L A R + + D + LW I K N HT +V +
Sbjct: 115 GHSHFVSDVSLS-ADSRYVLSSSWDATLRLWDIKKGNTTRRFISHTRDALAVAFSPDNRQ 291
Query: 78 IVAGSQSGSIRVWD-LEAAKILRTLMGHKANICSLDFHPYGE--FVASGSQDTNIKLWDI 134
I +G + ++++W+ + K H+ + + FH + V S S D IK+WD
Sbjct: 292 IASGGRDKALKIWNTVGECKFTVDANSHQDWVTCVKFHQDAKSPLVVSASMDKTIKVWDN 471
Query: 135 RRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNV 194
+ + GH + + + +LAS + D V W++ G + + VN
Sbjct: 472 QTMTLKHTFVGHKTQINAIDLALKTYYLASGSKDGIVMTWNIQNGTFLGKIDCDC-EVNA 648
Query: 195 VEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEP 231
V+F PN+Y L G+S+ I+ WDL + + I P
Sbjct: 649 VKFSPNKYWLFVGTSE-GIQIWDLPNQKKIKDIRASP 756
>12806
Length = 961
Score = 92.4 bits (228), Expect = 5e-19, Method: Compositional matrix adjust.
Identities = 53/214 (24%), Positives = 106/214 (49%), Gaps = 8/214 (3%)
Frame = +3
Query: 58 SLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYG 117
+LTGH+ + + L+ ++ S ++R+WD++ + H ++ ++ F P
Sbjct: 150 TLTGHSHFISDLALSADSRFALSSSWDATLRLWDIKKGSTTSRFINHTRDVLTVAFSPDN 329
Query: 118 EFVASGSQDTNIKLWDIRRKGCVFRY--RGHSQAVRCLRFSPDGK--WLASAADDHTVKL 173
+ASG +D N+K+W+I + C + H+ V C+RF D K + SA++D T+K+
Sbjct: 330 RQIASGGRDKNLKIWNIMGE-CKYTVDANAHTDWVTCVRFHQDTKNPIVVSASNDKTIKV 506
Query: 174 WDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGP 233
WD + + F GH + ++ N L SGS D W++ + V I+ +
Sbjct: 507 WDNHTMTLKNTFVGHKAQITALDMSTN--YLVSGSKDGIAMTWNVAEGSFVGKIDCDD-Q 677
Query: 234 VRSVLFNPDG----CCLYSGCQDSLRVYGWEPER 263
+ ++ FN + L+ G Q+ ++++ + E+
Sbjct: 678 INAIKFNIENNKKKVWLFIGTQNGIQIWDYSGEK 779
Score = 85.5 bits (210), Expect = 6e-17, Method: Compositional matrix adjust.
Identities = 63/241 (26%), Positives = 106/241 (43%), Gaps = 13/241 (5%)
Frame = +3
Query: 67 ESVRLNTPEELIVAGSQSGSIRVWDLEAAKI----------LRTLMGHKANICSLDFHPY 116
E V + +++G + +I VWDL K +TL GH I L
Sbjct: 21 EQVVDGATKPFLISGGRDNNIIVWDL*PKKDGDEDQTWGVPRKTLTGHSHFISDLALSAD 200
Query: 117 GEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDL 176
F S S D ++LWDI++ R+ H++ V + FSPD + +AS D +K+W++
Sbjct: 201 SRFALSSSWDATLRLWDIKKGSTTSRFINHTRDVLTVAFSPDNRQIASGGRDKNLKIWNI 380
Query: 177 TAG-KMMSEFPGHTGPVNVVEFHPNEY--LLASGSSDRTIRFWDLEKFQVVSCIEGEPGP 233
K + HT V V FH + ++ S S+D+TI+ WD + + G
Sbjct: 381 MGECKYTVDANAHTDWVTCVRFHQDTKNPIVVSASNDKTIKVWDNHTMTLKNTFVGHKAQ 560
Query: 234 VRSVLFNPDGCCLYSGCQDSLRVYGWEPERCFDVVLVNWGKVADLAICNDQLIGVAFSQS 293
+ ++ + + L SG +D + + E F GK+ C+DQ+ + F+
Sbjct: 561 ITALDMSTN--YLVSGSKDGIAMTWNVAEGSFV------GKID----CDDQINAIKFNIE 704
Query: 294 N 294
N
Sbjct: 705 N 707
>13335
Length = 863
Score = 89.7 bits (221), Expect = 3e-18, Method: Compositional matrix adjust.
Identities = 60/215 (27%), Positives = 96/215 (44%), Gaps = 24/215 (11%)
Frame = +1
Query: 64 SPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASG 123
S + + + +V+GS +I +W++ K++R+ +GH+ ++ +L + P G ++ SG
Sbjct: 64 SSIRVCKFSPSSSHLVSGSDDDTICMWEVATQKLVRSYVGHEDSVMALAYSPNGHYLVSG 243
Query: 124 SQDTNIKLWDIRRKGC---VFRYRGHSQAVRCLRFSPD------------GKWLASAADD 168
S + ++ +WD C R H V C FSP LA+ D
Sbjct: 244 SPNGDLYVWDASFGHCRHLTLRVDAHDLGVTCCEFSPTFGTACAENSSTCNLLLATGGKD 423
Query: 169 HTVKLWDLTAGKMMSE--------FPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEK 220
+ +KLW +A E GH+ V F P+ LLASGS D+++R WD K
Sbjct: 424 NLIKLWTFSAQVGSPEVTLQCRDILSGHSDLVMACAFSPSSALLASGSFDKSVRLWDSVK 603
Query: 221 FQVVSCIEG-EPGPVRSVLFNPDGCCLYSGCQDSL 254
+ IE V F+ DG L SG D +
Sbjct: 604 GVALFSIEACHSRFVTCCAFSIDGTLLASGSMDRI 708
Score = 79.0 bits (193), Expect = 5e-15, Method: Compositional matrix adjust.
Identities = 59/207 (28%), Positives = 86/207 (41%), Gaps = 24/207 (11%)
Frame = +1
Query: 36 LATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAA 95
L +G DD + +W + + S GH V ++ + +V+GS +G + VWD
Sbjct: 106 LVSGSDDDTICMWEVATQKLVRSYVGHEDSVMALAYSPNGHYLVSGSPNGDLYVWDASFG 285
Query: 96 KILRTLM---GHKANICSLDFHP-YGE-----------FVASGSQDTNIKLWDIRRK--- 137
+ H + +F P +G +A+G +D IKLW +
Sbjct: 286 HCRHLTLRVDAHDLGVTCCEFSPTFGTACAENSSTCNLLLATGGKDNLIKLWTFSAQVGS 465
Query: 138 -----GCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAG-KMMSEFPGHTGP 191
C GHS V FSP LAS + D +V+LWD G + S H+
Sbjct: 466 PEVTLQCRDILSGHSDLVMACAFSPSSALLASGSFDKSVRLWDSVKGVALFSIEACHSRF 645
Query: 192 VNVVEFHPNEYLLASGSSDRTIRFWDL 218
V F + LLASGS DR I+ W L
Sbjct: 646 VTCCAFSIDGTLLASGSMDRIIKIWKL 726
Score = 65.5 bits (158), Expect = 7e-11, Method: Compositional matrix adjust.
Identities = 51/196 (26%), Positives = 79/196 (40%), Gaps = 25/196 (12%)
Frame = +1
Query: 87 IRVWDLEAAKILRTLM-GHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRG 145
+ VWD++ I K++I F P + SGS D I +W++ + V Y G
Sbjct: 4 VIVWDVKTGSIKGEYQHASKSSIRVCKFSPSSSHLVSGSDDDTICMWEVATQKLVRSYVG 183
Query: 146 HSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAG---KMMSEFPGHTGPVNVVEFHPN-- 200
H +V L +SP+G +L S + + + +WD + G + H V EF P
Sbjct: 184 HEDSVMALAYSPNGHYLVSGSPNGDLYVWDASFGHCRHLTLRVDAHDLGVTCCEFSPTFG 363
Query: 201 ----------EYLLASGSSDRTIRFWDLEK--------FQVVSCIEGEPGPVRSVLFNPD 242
LLA+G D I+ W Q + G V + F+P
Sbjct: 364 TACAENSSTCNLLLATGGKDNLIKLWTFSAQVGSPEVTLQCRDILSGHSDLVMACAFSPS 543
Query: 243 GCCLYSGCQD-SLRVY 257
L SG D S+R++
Sbjct: 544 SALLASGSFDKSVRLW 591
Score = 59.3 bits (142), Expect = 5e-09, Method: Compositional matrix adjust.
Identities = 43/143 (30%), Positives = 65/143 (45%), Gaps = 9/143 (6%)
Frame = +1
Query: 44 RVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAA-------- 95
RV+ + C S T T+ E+ +T L+ G + I++W A
Sbjct: 307 RVDAHDLGVTCCEFSPTFGTACAENS--STCNLLLATGGKDNLIKLWTFSAQVGSPEVTL 480
Query: 96 KILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRG-HSQAVRCLR 154
+ L GH + + F P +ASGS D +++LWD + +F HS+ V C
Sbjct: 481 QCRDILSGHSDLVMACAFSPSSALLASGSFDKSVRLWDSVKGVALFSIEACHSRFVTCCA 660
Query: 155 FSPDGKWLASAADDHTVKLWDLT 177
FS DG LAS + D +K+W LT
Sbjct: 661 FSIDGTLLASGSMDRIIKIWKLT 729
Score = 28.9 bits (63), Expect = 6.0, Method: Compositional matrix adjust.
Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 4/76 (5%)
Frame = +1
Query: 21 SNVSSLVLGKA---SGRLLATGGDDCRVNLWSINKPNCIMSLTG-HTSPVESVRLNTPEE 76
S S LV+ A S LLA+G D V LW K + S+ H+ V +
Sbjct: 499 SGHSDLVMACAFSPSSALLASGSFDKSVRLWDSVKGVALFSIEACHSRFVTCCAFSIDGT 678
Query: 77 LIVAGSQSGSIRVWDL 92
L+ +GS I++W L
Sbjct: 679 LLASGSMDRIIKIWKL 726
>17602
Length = 481
Score = 85.1 bits (209), Expect = 9e-17, Method: Compositional matrix adjust.
Identities = 42/134 (31%), Positives = 70/134 (52%), Gaps = 4/134 (2%)
Frame = +3
Query: 47 LWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLM-GHK 105
+W + C+ +L H+ PV +V N LIV+ S G R+WD + + L TL+
Sbjct: 6 IWDVKTGKCLKTLPAHSDPVTAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLXTLIDDDN 185
Query: 106 ANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCL--RFS-PDGKWL 162
+ + F P G+++ + + D +KLWD + C+ Y GH C+ FS GKW+
Sbjct: 186 PPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYVGHRNEKYCIFANFSVTGGKWI 365
Query: 163 ASAADDHTVKLWDL 176
S ++D+ V +W+L
Sbjct: 366 VSGSEDNMVYIWNL 407
Score = 72.0 bits (175), Expect = 8e-13, Method: Compositional matrix adjust.
Identities = 39/135 (28%), Positives = 68/135 (50%), Gaps = 4/135 (2%)
Frame = +3
Query: 88 RVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRY-RGH 146
R+WD++ K L+TL H + ++ F+ G + S S D ++WD C+
Sbjct: 3 RIWDVKTGKCLKTLPAHSDPVTAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLXTLIDDD 182
Query: 147 SQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFH---PNEYL 203
+ V ++FSP+GK++ +A D+T+KLWD + GK + + GH + +
Sbjct: 183 NPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYVGHRNEKYCIFANFSVTGGKW 362
Query: 204 LASGSSDRTIRFWDL 218
+ SGS D + W+L
Sbjct: 363 IVSGSEDNMVYIWNL 407
Score = 53.5 bits (127), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 28/96 (29%), Positives = 50/96 (52%), Gaps = 2/96 (2%)
Frame = +3
Query: 172 KLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVV-SCIEGE 230
++WD+ GK + P H+ PV V F+ + L+ S S D R WD Q + + I+ +
Sbjct: 3 RIWDVKTGKCLKTLPAHSDPVTAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLXTLIDDD 182
Query: 231 PGPVRSVLFNPDGCCLYSGCQD-SLRVYGWEPERCF 265
PV V F+P+G + + D +L+++ + +C
Sbjct: 183 NPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCL 290
Score = 52.0 bits (123), Expect = 8e-07, Method: Compositional matrix adjust.
Identities = 37/153 (24%), Positives = 74/153 (48%), Gaps = 7/153 (4%)
Frame = +3
Query: 8 KTAWKLQEIVAHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSP-V 66
KT L+ + AH+ V+++ + G L+ + D +W C+ +L +P V
Sbjct: 18 KTGKCLKTLPAHSDPVTAVHFNR-DGSLIVSSSYDGLCRIWDTASGQCLXTLIDDDNPPV 194
Query: 67 ESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPY----GEFVAS 122
V+ + + I+A + ++++WD K L+T +GH+ + F + G+++ S
Sbjct: 195 SFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYVGHRNEKYCI-FANFSVTGGKWIVS 371
Query: 123 GSQDTNIKLWDIRRKGCVFRYRGHSQ--AVRCL 153
GS+D + +W++ +G G + AV CL
Sbjct: 372 GSEDNMVYIWNLLDQGDSTEATGSHRRGAVLCL 470
>02147
Length = 1547
Score = 81.6 bits (200), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 60/245 (24%), Positives = 101/245 (41%), Gaps = 41/245 (16%)
Frame = +2
Query: 54 NCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDF 113
+ I + GH V LN G+ S ++WD E + L+T HK + S+DF
Sbjct: 146 DWIGTFEGHKGAVWGATLNREATRAATGAADFSAKIWDAEKGEELQTF-SHKHIVKSVDF 322
Query: 114 HPYGEFVASGSQDTNIKLWDIRRKGCVFR-YRGHSQAVRCLRFSPDGKWLASAADDHTVK 172
G + +GS + +K++D+ + + GH+ ++ F DGK + SA+DD TV+
Sbjct: 323 SHDGTALLTGSNEKLLKVFDLVNTDAEPKSFAGHTSNIKGALFLSDGKRIISASDDKTVR 502
Query: 173 LWDLTAGKMMSEFPGHT---------------------------------------GPVN 193
LW L + + + T P++
Sbjct: 503 LWSLETCQEVQQLTFDTPPTSLTLSPDKNTIIVTHSQNIAFYQADTLREMKKFEAEAPIS 682
Query: 194 VVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVLFNPDGCCLYSGCQD- 252
H +E +G D + +D E + + +G GPV V F+PDG SG +D
Sbjct: 683 SASLHQSERFFVAGGEDFKMYKFDYETGKEIESFKGHFGPVHCVRFSPDGELYASGSEDG 862
Query: 253 SLRVY 257
+LR++
Sbjct: 863 TLRLW 877
Score = 73.6 bits (179), Expect = 3e-13, Method: Compositional matrix adjust.
Identities = 46/167 (27%), Positives = 81/167 (48%)
Frame = +2
Query: 14 QEIVAHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNT 73
+ H SN+ L + G+ + + DD V LWS+ + LT T P S+ L +
Sbjct: 407 KSFAGHTSNIKG-ALFLSDGKRIISASDDKTVRLWSLETCQEVQQLTFDTPPT-SLTL-S 577
Query: 74 PEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWD 133
P++ + + S +I + + + ++ +A I S H F +G +D + +D
Sbjct: 578 PDKNTIIVTHSQNIAFYQADTLREMKKFEA-EAPISSASLHQSERFFVAGGEDFKMYKFD 754
Query: 134 IRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGK 180
+ ++GH V C+RFSPDG+ AS ++D T++LW T G+
Sbjct: 755 YETGKEIESFKGHFGPVHCVRFSPDGELYASGSEDGTLRLWQTTIGR 895
Score = 65.9 bits (159), Expect = 5e-11, Method: Compositional matrix adjust.
Identities = 57/239 (23%), Positives = 92/239 (38%), Gaps = 40/239 (16%)
Frame = +2
Query: 18 AHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEEL 77
H V L + + R ATG D +W K + + + H V+SV +
Sbjct: 167 GHKGAVWGATLNREATRA-ATGAADFSAKIWDAEKGEELQTFS-HKHIVKSVDFSHDGTA 340
Query: 78 IVAGSQSGSIRVWDLEAAKIL-RTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRR 136
++ GS ++V+DL ++ GH +NI F G+ + S S D ++LW +
Sbjct: 341 LLTGSNEKLLKVFDLVNTDAEPKSFAGHTSNIKGALFLSDGKRIISASDDKTVRLWSLET 520
Query: 137 KGCVFRYR-------------------GHSQAVRCL---------RFSPDG--------- 159
V + HSQ + +F +
Sbjct: 521 CQEVQQLTFDTPPTSLTLSPDKNTIIVTHSQNIAFYQADTLREMKKFEAEAPISSASLHQ 700
Query: 160 --KWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFW 216
++ + +D + +D GK + F GH GPV+ V F P+ L ASGS D T+R W
Sbjct: 701 SERFFVAGGEDFKMYKFDYETGKEIESFKGHFGPVHCVRFSPDGELYASGSEDGTLRLW 877
Score = 45.1 bits (105), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 39/165 (23%), Positives = 70/165 (42%), Gaps = 3/165 (1%)
Frame = +2
Query: 143 YRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEY 202
+ GH AV + + A+ A D + K+WD G+ + F H V V+F +
Sbjct: 161 FEGHKGAVWGATLNREATRAATGAADFSAKIWDAEKGEELQTFS-HKHIVKSVDFSHDGT 337
Query: 203 LLASGSSDRTIRFWDLEKFQVV-SCIEGEPGPVRSVLFNPDGCCLYSGCQD-SLRVYGWE 260
L +GS+++ ++ +DL G ++ LF DG + S D ++R+ W
Sbjct: 338 ALLTGSNEKLLKVFDLVNTDAEPKSFAGHTSNIKGALFLSDGKRIISASDDKTVRL--WS 511
Query: 261 PERCFDVVLVNWGK-VADLAICNDQLIGVAFSQSNVSSYVVDLTR 304
E C +V + + L + D+ + N++ Y D R
Sbjct: 512 LETCQEVQQLTFDTPPTSLTLSPDKNTIIVTHSQNIAFYQADTLR 646
Score = 38.5 bits (88), Expect = 0.008, Method: Compositional matrix adjust.
Identities = 25/90 (27%), Positives = 40/90 (44%)
Frame = +2
Query: 179 GKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVL 238
G + F GH G V + A+G++D + + WD EK + + V+SV
Sbjct: 143 GDWIGTFEGHKGAVWGATLNREATRAATGAADFSAKIWDAEKGEELQTFS-HKHIVKSVD 319
Query: 239 FNPDGCCLYSGCQDSLRVYGWEPERCFDVV 268
F+ DG L +G + L + FD+V
Sbjct: 320 FSHDGTALLTGSNEKLL-------KVFDLV 388
>03156
Length = 1014
Score = 80.5 bits (197), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 56/261 (21%), Positives = 110/261 (42%), Gaps = 10/261 (3%)
Frame = +1
Query: 18 AHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEEL 77
H ++ + G + + + D + +W + I GH V ++ LNT L
Sbjct: 49 GHDREITKVCYGASCNGMFSASRDK-TIKMWQRGNSHSIRDFIGHDMVVTAIHLNTDNTL 225
Query: 78 IVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRK 137
+ +GS+ ++R+WD+E LR + + + + P + +D ++++D R
Sbjct: 226 LCSGSRDNTVRIWDVETGACLRQNNIPQNLVTDVKWLPGSHLIIQAGEDKEVRIYDSRTL 405
Query: 138 GCVFRYRGHSQAVRCLRFSPDGKWLASAADDH-----TVKLWDLTAGKMMSEFPGHTGPV 192
G V + + DG++ + ++ LW L+ G + +EF GH +
Sbjct: 406 GIVRSFTKKQYIQMSCDVTADGQFCLTCSNGFGGNGCEATLWQLSDGSIQNEFKGHREAI 585
Query: 193 NVVEFHPNEY---LLASGSSDRTIRFWDLEKFQVV--SCIEGEPGPVRSVLFNPDGCCLY 247
F P+ L+A+ S D ++R W++ + V EG GP+ S++ DG L
Sbjct: 586 EACLFLPSNQDMTLIATASRDCSVRVWNMFTKECVCEQNFEG-TGPLTSMIAYGDGSVLV 762
Query: 248 SGCQDSLRVYGWEPERCFDVV 268
++V + D+V
Sbjct: 763 GTFNLGVQVMSLNGQSSLDIV 825
Score = 53.5 bits (127), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 24/78 (30%), Positives = 40/78 (51%)
Frame = +1
Query: 142 RYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNE 201
R+ GH + + + + + SA+ D T+K+W + +F GH V + + +
Sbjct: 40 RWTGHDREITKVCYGASCNGMFSASRDKTIKMWQRGNSHSIRDFIGHDMVVTAIHLNTDN 219
Query: 202 YLLASGSSDRTIRFWDLE 219
LL SGS D T+R WD+E
Sbjct: 220 TLLCSGSRDNTVRIWDVE 273
Score = 32.3 bits (72), Expect = 0.62, Method: Compositional matrix adjust.
Identities = 21/88 (23%), Positives = 38/88 (43%), Gaps = 1/88 (1%)
Frame = +1
Query: 179 GKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVL 238
G++ + GH + V + + + S S D+TI+ W + G V ++
Sbjct: 25 GRLEDRWTGHDREITKVCYGASCNGMFSASRDKTIKMWQRGNSHSIRDFIGHDMVVTAIH 204
Query: 239 FNPDGCCLYSGCQD-SLRVYGWEPERCF 265
N D L SG +D ++R++ E C
Sbjct: 205 LNTDNTLLCSGSRDNTVRIWDVETGACL 288
>01327
Length = 2215
Score = 80.1 bits (196), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 56/262 (21%), Positives = 110/262 (41%), Gaps = 10/262 (3%)
Frame = +3
Query: 17 VAHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEE 76
H ++ + G + + + D + +W + I GH V ++ LNT
Sbjct: 156 TGHDREITKVCYGASCNGMFSASRDK-TIKMWQRGNSHSIRDFIGHDMVVTAIHLNTDNT 332
Query: 77 LIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRR 136
L+ +GS+ ++R+WD+E LR + + + + P + +D ++++D R
Sbjct: 333 LLCSGSRDNTVRIWDVETGACLRQNNIPQNLVTDVKWLPGSHLIIQAGEDKEVRIYDSRT 512
Query: 137 KGCVFRYRGHSQAVRCLRFSPDGKWLASAADDH-----TVKLWDLTAGKMMSEFPGHTGP 191
G V + + DG++ + ++ LW L+ G + +EF GH
Sbjct: 513 LGIVRSFTKKQYIQMSCDVTADGQFCLTCSNGFGGNGCEATLWQLSDGSIQNEFKGHREA 692
Query: 192 VNVVEFHPNEY---LLASGSSDRTIRFWDLEKFQVV--SCIEGEPGPVRSVLFNPDGCCL 246
+ F P+ L+A+ S D ++R W++ + V EG GP+ S++ DG L
Sbjct: 693 IEACLFLPSNQDMTLIATASRDCSVRVWNMFTKECVCEQNFEG-TGPLTSMIAYGDGSVL 869
Query: 247 YSGCQDSLRVYGWEPERCFDVV 268
++V + D+V
Sbjct: 870 VGTFNLGVQVMSLNGQSSLDIV 935
Score = 61.6 bits (148), Expect = 9e-10, Method: Compositional matrix adjust.
Identities = 34/148 (22%), Positives = 67/148 (45%)
Frame = +3
Query: 77 LIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRR 136
L ++GS+ S+ ++D + ++ GH I + + + S S+D IK+W
Sbjct: 81 LCLSGSKDKSVVLYDYQNGRLEDRWTGHDREITKVCYGASCNGMFSASRDKTIKMWQRGN 260
Query: 137 KGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVE 196
+ + GH V + + D L S + D+TV++WD+ G + + V V+
Sbjct: 261 SHSIRDFIGHDMVVTAIHLNTDNTLLCSGSRDNTVRIWDVETGACLRQNNIPQNLVTDVK 440
Query: 197 FHPNEYLLASGSSDRTIRFWDLEKFQVV 224
+ P +L+ D+ +R +D +V
Sbjct: 441 WLPGSHLIIQAGEDKEVRIYDSRTLGIV 524
Score = 40.4 bits (93), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 26/103 (25%), Positives = 46/103 (44%), Gaps = 1/103 (0%)
Frame = +3
Query: 164 SAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQV 223
S + D +V L+D G++ + GH + V + + + S S D+TI+ W
Sbjct: 90 SGSKDKSVVLYDYQNGRLEDRWTGHDREITKVCYGASCNGMFSASRDKTIKMWQRGNSHS 269
Query: 224 VSCIEGEPGPVRSVLFNPDGCCLYSGCQD-SLRVYGWEPERCF 265
+ G V ++ N D L SG +D ++R++ E C
Sbjct: 270 IRDFIGHDMVVTAIHLNTDNTLLCSGSRDNTVRIWDVETGACL 398
>27465
Length = 658
Score = 79.3 bits (194), Expect = 4e-15, Method: Compositional matrix adjust.
Identities = 38/119 (31%), Positives = 63/119 (52%), Gaps = 1/119 (0%)
Frame = -1
Query: 59 LTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDF-HPYG 117
L H P+ +V N + GS + ++WD +A+ L TL GH+ + ++ F +P+G
Sbjct: 373 LRAHILPLTNVAFNKSGSSFITGSYDRTCKIWDTASAEELHTLEGHRNVVYAIAFNNPFG 194
Query: 118 EFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDL 176
+ V +GS D KLW C RGH+ + C+ F+P +A+ + D T +LWD+
Sbjct: 193 DKVITGSFDKTCKLWSTADGKCYHTLRGHTAEIVCVSFNPSSTLIATGSMDTTCRLWDV 17
Score = 75.9 bits (185), Expect = 5e-14, Method: Compositional matrix adjust.
Identities = 41/127 (32%), Positives = 61/127 (48%), Gaps = 1/127 (0%)
Frame = -1
Query: 97 ILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFS 156
+ + L H + ++ F+ G +GS D K+WD + GH V + F+
Sbjct: 385 LFKVLRAHILPLTNVAFNKSGSSFITGSYDRTCKIWDTASAEELHTLEGHRNVVYAIAFN 206
Query: 157 -PDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRF 215
P G + + + D T KLW GK GHT + V F+P+ L+A+GS D T R
Sbjct: 205 NPFGDKVITGSFDKTCKLWSTADGKCYHTLRGHTAEIVCVSFNPSSTLIATGSMDTTCRL 26
Query: 216 WDLEKFQ 222
WD+EK Q
Sbjct: 25 WDVEKAQ 5
Score = 66.6 bits (161), Expect = 3e-11, Method: Compositional matrix adjust.
Identities = 35/120 (29%), Positives = 58/120 (48%), Gaps = 1/120 (0%)
Frame = -1
Query: 18 AHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTP-EE 76
AH ++++ K SG TG D +W + +L GH + V ++ N P +
Sbjct: 367 AHILPLTNVAFNK-SGSSFITGSYDRTCKIWDTASAEELHTLEGHRNVVYAIAFNNPFGD 191
Query: 77 LIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRR 136
++ GS + ++W K TL GH A I + F+P +A+GS DT +LWD+ +
Sbjct: 190 KVITGSFDKTCKLWSTADGKCYHTLRGHTAEIVCVSFNPSSTLIATGSMDTTCRLWDVEK 11
Score = 53.1 bits (126), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 28/90 (31%), Positives = 42/90 (46%)
Frame = -1
Query: 7 TKTAWKLQEIVAHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPV 66
T +A +L + H + V ++ G + TG D LWS C +L GHT+ +
Sbjct: 274 TASAEELHTLEGHRNVVYAIAFNNPFGDKVITGSFDKTCKLWSTADGKCYHTLRGHTAEI 95
Query: 67 ESVRLNTPEELIVAGSQSGSIRVWDLEAAK 96
V N LI GS + R+WD+E A+
Sbjct: 94 VCVSFNPSSTLIATGSMDTTCRLWDVEKAQ 5
Score = 48.1 bits (113), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 26/111 (23%), Positives = 47/111 (42%), Gaps = 1/111 (0%)
Frame = -1
Query: 144 RGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFH-PNEY 202
R H + + F+ G + + D T K+WD + + + GH V + F+ P
Sbjct: 370 RAHILPLTNVAFNKSGSSFITGSYDRTCKIWDTASAEELHTLEGHRNVVYAIAFNNPFGD 191
Query: 203 LLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVLFNPDGCCLYSGCQDS 253
+ +GS D+T + W + + G + V FNP + +G D+
Sbjct: 190 KVITGSFDKTCKLWSTADGKCYHTLRGHTAEIVCVSFNPSSTLIATGSMDT 38
Score = 35.4 bits (80), Expect = 0.068, Method: Compositional matrix adjust.
Identities = 25/104 (24%), Positives = 46/104 (44%), Gaps = 2/104 (1%)
Frame = -1
Query: 167 DDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSC 226
DDH L+ + H P+ V F+ + +GS DRT + WD + +
Sbjct: 403 DDHHFYLFKV--------LRAHILPLTNVAFNKSGSSFITGSYDRTCKIWDTASAEELHT 248
Query: 227 IEGEPGPVRSVLF-NPDGCCLYSGCQD-SLRVYGWEPERCFDVV 268
+EG V ++ F NP G + +G D + +++ +C+ +
Sbjct: 247 LEGHRNVVYAIAFNNPFGDKVITGSFDKTCKLWSTADGKCYHTL 116
>29912
Length = 510
Score = 78.2 bits (191), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 58/159 (36%), Positives = 82/159 (51%), Gaps = 19/159 (11%)
Frame = +3
Query: 74 PEELIVA------------GSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVA 121
PEE I A G+ +G ++VWD+ K LRT+ GH A + SL ++ + V+
Sbjct: 6 PEEYIGAVSWIKEGNYLALGTSTGEVQVWDVTQQKKLRTMAGHAARVGSLSWNSF--IVS 179
Query: 122 SGSQDTNIKLWDIR-RKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLW--DLTA 178
SGS+ NI D+R V GHSQ V LR+SPDGK+LAS A+D+ + +W +T
Sbjct: 180 SGSRSGNIHHHDVRVADHHVGTLSGHSQEVCGLRWSPDGKYLASGANDNLLCVWPAQVTG 359
Query: 179 GKM---MSEFPGHTGPVNVVEFHPNE-YLLASGSSDRTI 213
G + F H V + + P + LASG D I
Sbjct: 360 GNSTQPLHTFSQHQAAVKALAWCPWQPSXLASGGGDVLI 476
Score = 59.3 bits (142), Expect = 4e-09, Method: Compositional matrix adjust.
Identities = 37/131 (28%), Positives = 66/131 (50%), Gaps = 6/131 (4%)
Frame = +3
Query: 33 GRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDL 92
G LA G V +W + + + ++ GH + V S+ N+ ++ +GS+SG+I D+
Sbjct: 45 GNYLALGTSTGEVQVWDVTQQKKLRTMAGHAARVGSLSWNS--FIVSSGSRSGNIHHHDV 218
Query: 93 EAA-KILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGC-----VFRYRGH 146
A + TL GH +C L + P G+++ASG+ D + +W + G + + H
Sbjct: 219 RVADHHVGTLSGHSQEVCGLRWSPDGKYLASGANDNLLCVWPAQVTGGNSTQPLHTFSQH 398
Query: 147 SQAVRCLRFSP 157
AV+ L + P
Sbjct: 399 QAAVKALAWCP 431
Score = 43.5 bits (101), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 29/111 (26%), Positives = 51/111 (45%), Gaps = 1/111 (0%)
Frame = +3
Query: 145 GHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLL 204
G + + + + +G +LA V++WD+T K + GH V + + N +++
Sbjct: 3 GPEEYIGAVSWIKEGNYLALGTSTGEVQVWDVTQQKKLRTMAGHAARVGSLSW--NSFIV 176
Query: 205 ASGSSDRTIRFWDLE-KFQVVSCIEGEPGPVRSVLFNPDGCCLYSGCQDSL 254
+SGS I D+ V + G V + ++PDG L SG D+L
Sbjct: 177 SSGSRSGNIHHHDVRVADHHVGTLSGHSQEVCGLRWSPDGKYLASGANDNL 329
>12574
Length = 521
Score = 75.1 bits (183), Expect = 8e-14, Method: Composition-based stats.
Identities = 39/109 (35%), Positives = 57/109 (52%)
Frame = +3
Query: 100 TLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDG 159
TL GH + ++ F P G+++AS S D IK+W GH + + +S D
Sbjct: 171 TLAGHTKALSAVKFSPNGDWLASSSADKLIKIWGAYDGKFEKTIAGHKLGLSDVAWSSDS 350
Query: 160 KWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGS 208
K L SA+DD T+K+W+ + GK M GH+ V F+P L+ SGS
Sbjct: 351 KLLCSASDDKTLKIWEFSTGKCMKTLKGHSNYVFCCNFNPQSNLIVSGS 497
Score = 72.0 bits (175), Expect = 7e-13, Method: Composition-based stats.
Identities = 34/109 (31%), Positives = 57/109 (52%)
Frame = +3
Query: 141 FRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPN 200
F GH++A+ ++FSP+G WLAS++ D +K+W GK GH ++ V + +
Sbjct: 168 FTLAGHTKALSAVKFSPNGDWLASSSADKLIKIWGAYDGKFEKTIAGHKLGLSDVAWSSD 347
Query: 201 EYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVLFNPDGCCLYSG 249
LL S S D+T++ W+ + + ++G V FNP + SG
Sbjct: 348 SKLLCSASDDKTLKIWEFSTGKCMKTLKGHSNYVFCCNFNPQSNLIVSG 494
Score = 60.1 bits (144), Expect = 3e-09, Method: Composition-based stats.
Identities = 27/109 (24%), Positives = 52/109 (47%)
Frame = +3
Query: 58 SLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYG 117
+L GHT + +V+ + + + + S I++W K +T+ GHK + + +
Sbjct: 171 TLAGHTKALSAVKFSPNGDWLASSSADKLIKIWGAYDGKFEKTIAGHKLGLSDVAWSSDS 350
Query: 118 EFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAA 166
+ + S S D +K+W+ C+ +GHS V C F+P + S +
Sbjct: 351 KLLCSASDDKTLKIWEFSTGKCMKTLKGHSNYVFCCNFNPQSNLIVSGS 497
Score = 49.3 bits (116), Expect = 5e-06, Method: Composition-based stats.
Identities = 26/117 (22%), Positives = 53/117 (45%)
Frame = +3
Query: 8 KTAWKLQEIVAHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVE 67
K + L+ +A + S V +G LA+ D + +W ++ GH +
Sbjct: 147 KPTYTLKFTLAGHTKALSAVKFSPNGDWLASSSADKLIKIWGAYDGKFEKTIAGHKLGLS 326
Query: 68 SVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGS 124
V ++ +L+ + S ++++W+ K ++TL GH + +F+P + SGS
Sbjct: 327 DVAWSSDSKLLCSASDDKTLKIWEFSTGKCMKTLKGHSNYVFCCNFNPQSNLIVSGS 497
Score = 38.9 bits (89), Expect = 0.006, Method: Composition-based stats.
Identities = 23/83 (27%), Positives = 40/83 (48%), Gaps = 1/83 (1%)
Frame = +3
Query: 187 GHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVLFNPDGCCL 246
GHT ++ V+F PN LAS S+D+ I+ W + I G + V ++ D L
Sbjct: 180 GHTKALSAVKFSPNGDWLASSSADKLIKIWGAYDGKFEKTIAGHKLGLSDVAWSSDSKLL 359
Query: 247 YSGCQD-SLRVYGWEPERCFDVV 268
S D +L+++ + +C +
Sbjct: 360 CSASDDKTLKIWEFSTGKCMKTL 428
>19498
Length = 903
Score = 67.4 bits (163), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 46/141 (32%), Positives = 69/141 (48%), Gaps = 22/141 (15%)
Frame = -1
Query: 146 HSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAG-----------------KMMSEFPGH 188
H V C+R+S +GK+LAS DD + +W ++ G + ++ GH
Sbjct: 789 HLGCVNCVRWSENGKFLASGGDDKLIMIWQISRGFGSGKSFGSNVTILEHWRSVATLRGH 610
Query: 189 TGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKF-QVVSCIEGEPGPVRSVLFNPDGCCLY 247
G V + + P + LAS S D TI W+ KF + V+ I G G V+ V ++P G L
Sbjct: 609 AGDVLDLAWSPQDLWLASCSVDNTIVVWNALKFSEQVAVIRGHAGMVKGVTWDPVGRYLA 430
Query: 248 SGCQD-SLRVY---GWEPERC 264
S D +LRV+ W+ E C
Sbjct: 429 SQSDDKTLRVWRTSDWKEETC 367
Score = 67.0 bits (162), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 51/177 (28%), Positives = 81/177 (45%), Gaps = 24/177 (13%)
Frame = -1
Query: 91 DLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRK------------- 137
D + ++L + H + + + G+F+ASG D I +W I R
Sbjct: 828 DDDVPRVLCQMDSHLGCVNCVRWSENGKFLASGGDDKLIMIWQISRGFGSGKSFGSNVTI 649
Query: 138 ----GCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWD-LTAGKMMSEFPGHTGPV 192
V RGH+ V L +SP WLAS + D+T+ +W+ L + ++ GH G V
Sbjct: 648 LEHWRSVATLRGHAGDVLDLAWSPQDLWLASCSVDNTIVVWNALKFSEQVAVIRGHAGMV 469
Query: 193 NVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEG---EPGPVRSVL---FNPDG 243
V + P LAS S D+T+R W ++ +C++ E G VL ++PDG
Sbjct: 468 KGVTWDPVGRYLASQSDDKTLRVWRTSDWKEETCVKSCFKECGGTTHVLRLNWSPDG 298
Score = 64.7 bits (156), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 62/250 (24%), Positives = 111/250 (44%), Gaps = 47/250 (18%)
Frame = -1
Query: 32 SGRLLATGGDDCRVNLWSINKP-----------------NCIMSLTGHTSPVESVRLNTP 74
+G+ LA+GGDD + +W I++ + +L GH V + +
Sbjct: 753 NGKFLASGGDDKLIMIWQISRGFGSGKSFGSNVTILEHWRSVATLRGHAGDVLDLAWSPQ 574
Query: 75 EELIVAGSQSGSIRVWD-LEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLW- 132
+ + + S +I VW+ L+ ++ + + GH + + + P G ++AS S D +++W
Sbjct: 573 DLWLASCSVDNTIVVWNALKFSEQVAVIRGHAGMVKGVTWDPVGRYLASQSDDKTLRVWR 394
Query: 133 --DIRRKGCV---FRYRGHSQAVRCLRFSPDGKWLASAADDH----TVKLWDLTAGKMMS 183
D + + CV F+ G + V L +SPDG + SA + T ++ +
Sbjct: 393 TSDWKEETCVKSCFKECGGTTHVLRLNWSPDGNHVVSAHAMNNAXPTAQIIERNGWGTSL 214
Query: 184 EFPGHTGPVNVVEFHP--------------NEY-LLASGSSDRTIRFW--DLEKFQVV-- 224
+F GH + VV F+P +Y A GS DR++ W L + VV
Sbjct: 213 DFVGHRKAITVVRFNPKILSKQIKKSAEKQQQYSCCAIGSKDRSLSIWLTALRRPLVVMH 34
Query: 225 SCIEGEPGPV 234
+C++ PG V
Sbjct: 33 ACLKVHPGCV 4
>02960
Length = 1577
Score = 65.5 bits (158), Expect = 7e-11, Method: Compositional matrix adjust.
Identities = 64/242 (26%), Positives = 103/242 (42%), Gaps = 38/242 (15%)
Frame = +2
Query: 38 TGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEE-----LIVAGSQSGSIRVWDL 92
+G D V LWS K IM++ GHTSPV+ V +E V GS + VW
Sbjct: 530 SGSYDNTVRLWS-TKGEAIMTIPGHTSPVKCVAWIKHDESSGVSTFVTGSHDQTALVWQW 706
Query: 93 E----AAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLW------------DIRR 136
+ + GH A++ + P + + +GS D +KLW D R
Sbjct: 707 QRETNEVDCRLSCRGHAASVDCVAVSPDSQQMCTGSWDKMLKLWSTDCNVDGDQSEDTER 886
Query: 137 KGC--------------VFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMM 182
V GH++AV +R+ D + +++ DH+++LWDL +
Sbjct: 887 PSKKKKSAKSTTQTRVPVLTLSGHAEAVSAVRW-LDPHRVVTSSWDHSLRLWDLHTAQQT 1063
Query: 183 SEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWD--LEKFQVVSC-IEGEPGPVRSVLF 239
S G ++V + P ++L +GS+DR +R D + + V C G V V +
Sbjct: 1064SLIQGSKAVLDVA-YSPLSHMLITGSADRHVRLVDPRCSEGETVKCAFTSHTGWVTGVDW 1240
Query: 240 NP 241
+P
Sbjct: 1241SP 1246
Score = 57.0 bits (136), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 52/210 (24%), Positives = 89/210 (42%), Gaps = 36/210 (17%)
Frame = +2
Query: 79 VAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGE------FVASGSQDTNIKLW 132
++GS ++R+W + I+ T+ GH + + + + + E FV +GS D +W
Sbjct: 527 LSGSYDNTVRLWSTKGEAIM-TIPGHTSPVKCVAWIKHDESSGVSTFV-TGSHDQTALVW 700
Query: 133 DIRRK----GCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLW--DLTAGKMMSE-- 184
+R+ C RGH+ +V C+ SPD + + + + D +KLW D SE
Sbjct: 701 QWQRETNEVDCRLSCRGHAASVDCVAVSPDSQQMCTGSWDKMLKLWSTDCNVDGDQSEDT 880
Query: 185 ----------------------FPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQ 222
GH V+ V + + + + + S D ++R WDL Q
Sbjct: 881 ERPSKKKKSAKSTTQTRVPVLTLSGHAEAVSAVRW-LDPHRVVTSSWDHSLRLWDLHTAQ 1057
Query: 223 VVSCIEGEPGPVRSVLFNPDGCCLYSGCQD 252
S I+G V V ++P L +G D
Sbjct: 1058QTSLIQGSKA-VLDVAYSPLSHMLITGSAD 1144
Score = 50.8 bits (120), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 56/219 (25%), Positives = 92/219 (42%), Gaps = 37/219 (16%)
Frame = +2
Query: 36 LATGGDDCRVNLW----SINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVW- 90
TG D +W N+ +C +S GH + V+ V ++ + + GS +++W
Sbjct: 662 FVTGSHDQTALVWQWQRETNEVDCRLSCRGHAASVDCVAVSPDSQQMCTGSWDKMLKLWS 841
Query: 91 -----------DLEAAKI--------------LRTLMGHKANICS---LDFHPYGEFVAS 122
D E + TL GH + + LD H V +
Sbjct: 842 TDCNVDGDQSEDTERPSKKKKSAKSTTQTRVPVLTLSGHAEAVSAVRWLDPHR----VVT 1009
Query: 123 GSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWD--LTAGK 180
S D +++LWD+ +G S+AV + +SP L + + D V+L D + G+
Sbjct: 1010SSWDHSLRLWDLHTAQQTSLIQG-SKAVLDVAYSPLSHMLITGSADRHVRLVDPRCSEGE 1186
Query: 181 MMS-EFPGHTGPVNVVEFHPN-EYLLASGSSDRTIRFWD 217
+ F HTG V V++ P E+L SGS D ++ WD
Sbjct: 1187TVKCAFTSHTGWVTGVDWSPTREHLFLSGSYDNVLKLWD 1303
Score = 39.7 bits (91), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 29/100 (29%), Positives = 45/100 (45%), Gaps = 9/100 (9%)
Frame = +2
Query: 164 SAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNE-----YLLASGSSDRTIRFWDL 218
S + D+TV+LW T G+ + PGHT PV V + ++ +GS D+T W
Sbjct: 530 SGSYDNTVRLWS-TKGEAIMTIPGHTSPVKCVAWIKHDESSGVSTFVTGSHDQTALVWQW 706
Query: 219 EK-FQVVSC---IEGEPGPVRSVLFNPDGCCLYSGCQDSL 254
++ V C G V V +PD + +G D +
Sbjct: 707 QRETNEVDCRLSCRGHAASVDCVAVSPDSQQMCTGSWDKM 826
Score = 35.8 bits (81), Expect = 0.056, Method: Compositional matrix adjust.
Identities = 35/147 (23%), Positives = 54/147 (36%), Gaps = 46/147 (31%)
Frame = +2
Query: 56 IMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANI------- 108
+++L+GH V +VR P +V S S+R+WDL A+ + G KA +
Sbjct: 938 VLTLSGHAEAVSAVRWLDPHR-VVTSSWDHSLRLWDLHTAQQTSLIQGSKAVLDVAYSPL 1114
Query: 109 -------------------CS------------------LDFHPYGE-FVASGSQDTNIK 130
CS +D+ P E SGS D +K
Sbjct: 1115 SHMLITGSADRHVRLVDPRCSEGETVKCAFTSHTGWVTGVDWSPTREHLFLSGSYDNVLK 1294
Query: 131 LWDIRR-KGCVFRYRGHSQAVRCLRFS 156
LWD R K ++ H + + +S
Sbjct: 1295 LWDTRSPKATLYDMNWHEDRILAVDWS 1375
>01805
Length = 2124
Score = 64.7 bits (156), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 55/183 (30%), Positives = 76/183 (41%), Gaps = 26/183 (14%)
Frame = -1
Query: 111 LDFHPY----GEFVASGSQDTNIKLWDIRRKGCVF--------------------RYRGH 146
L+F Y G FVA GS + I++WD+ V GH
Sbjct: 756 LNFDGYDNAPGNFVAIGSMEPVIEIWDLDIMESVGPTLTLGSKPKKTKKKMKQKESVTGH 577
Query: 147 SQAVRCLRFSPDGKW-LASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPN-EYLL 204
+QAV L ++ + + LASA+ D TV LWDL+ GKM F H+ V +HP E L
Sbjct: 576 TQAVLDLSWNRNARHVLASASADTTVALWDLSEGKMAMNFTQHSREVQCCNWHPQEEQTL 397
Query: 205 ASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVLFNPDGCCLYSGCQDSLRVYGWEPERC 264
+GS D T++ D + G V ++N C D VY C
Sbjct: 396 LTGSFDNTVKVVDCRSAETCHKSWTVEGEVEKAVWNHHNPLQLLACTDKGMVY------C 235
Query: 265 FDV 267
FD+
Sbjct: 234 FDI 226
Score = 43.5 bits (101), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 37/166 (22%), Positives = 71/166 (42%), Gaps = 4/166 (2%)
Frame = -1
Query: 58 SLTGHTSPVESVRLN-TPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPY 116
S+TGHT V + N ++ + S ++ +WDL K+ H + ++HP
Sbjct: 591 SVTGHTQAVLDLSWNRNARHVLASASADTTVALWDLSEGKMAMNFTQHSREVQCCNWHPQ 412
Query: 117 GE-FVASGSQDTNIKLWDIRR-KGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLW 174
E + +GS D +K+ D R + C + + + + + L + D V +
Sbjct: 411 EEQTLLTGSFDNTVKVVDCRSAETCHKSWTVEGEVEKAVWNHHNPLQLLACTDKGMVYCF 232
Query: 175 DLTAGKMMSEFPGHTGPVNVVEFHPN-EYLLASGSSDRTIRFWDLE 219
D+ K + H+ V V L+ + S D+T++ WD++
Sbjct: 231 DIRHEKPVFSVGAHSSCVTGVCLSSQIPGLMITTSEDKTMKVWDIQ 94
>03395
Length = 2795
Score = 64.7 bits (156), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 42/206 (20%), Positives = 85/206 (41%), Gaps = 9/206 (4%)
Frame = +2
Query: 31 ASGRLLATGGDDCRVNLWSI--------NKPNCIMSLTGHTSPVESVRLNTPEELIVAGS 82
+ G L +GG + +V +W I + + + ++ H V +++++T + V+ S
Sbjct: 26 SCGTKLVSGGGEGQVRVWDIVKDMLTGKTRGDLVANMKEHKGKVTAIQIHTNDRCCVSAS 205
Query: 83 QSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFR 142
GS +WDL + ++ + C F + + D I W++ G +
Sbjct: 206 TDGSTIIWDLITNTRSQIVLANTLFKCVC-FGGKDLHILTSGTDHKIGYWEVGDGGLLRE 382
Query: 143 YRG-HSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNE 201
G + A+ + DG+ + + +D +KLW G++ GH+ + PN
Sbjct: 383 LEGSQTGAINTIDIDRDGQTILTGGEDSLLKLWRYNEGEVTHTGIGHSNQITKARICPNR 562
Query: 202 YLLASGSSDRTIRFWDLEKFQVVSCI 227
+ + SG D + W V C+
Sbjct: 563 HYIVSGGEDGALHIWKFPDGC*VDCL 640
>12960
Length = 550
Score = 64.3 bits (155), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 33/105 (31%), Positives = 54/105 (51%)
Frame = +2
Query: 113 FHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVK 172
F + + D ++KLW+ R+ + Y GH V + S D + S D TV
Sbjct: 197 FSVDSRYCMTCGSDKSVKLWNPHRELFLKTYIGHGHEVLDAQGSGDNSQICSGGIDKTVV 376
Query: 173 LWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWD 217
L+D+ +G+ + ++ H G VN V+F+ ++ SGS D T+R WD
Sbjct: 377 LFDVASGQALRKYRDHAGTVNCVKFNEESTVILSGSLDNTVRAWD 511
Score = 56.2 bits (134), Expect = 4e-08, Method: Compositional matrix adjust.
Identities = 38/136 (27%), Positives = 61/136 (44%)
Frame = +2
Query: 125 QDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSE 184
Q+TN+K RK + QAVR +RFS D ++ + D +VKLW+ +
Sbjct: 113 QNTNMKFELPDRKEVTINCK--QQAVRAVRFSVDSRYCMTCGSDKSVKLWNPHRELFLKT 286
Query: 185 FPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVLFNPDGC 244
+ GH V + + + SG D+T+ +D+ Q + G V V FN +
Sbjct: 287 YIGHGHEVLDAQGSGDNSQICSGGIDKTVVLFDVASGQALRKYRDHAGTVNCVKFNEEST 466
Query: 245 CLYSGCQDSLRVYGWE 260
+ SG D+ V W+
Sbjct: 467 VILSGSLDNT-VRAWD 511
Score = 53.5 bits (127), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 29/113 (25%), Positives = 55/113 (48%), Gaps = 2/113 (1%)
Frame = +2
Query: 65 PVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEF--VAS 122
V +VR + + S+++W+ L+T +GH + LD G+ + S
Sbjct: 179 AVRAVRFSVDSRYCMTCGSDKSVKLWNPHRELFLKTYIGHGHEV--LDAQGSGDNSQICS 352
Query: 123 GSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWD 175
G D + L+D+ + +YR H+ V C++F+ + + S + D+TV+ WD
Sbjct: 353 GGIDKTVVLFDVASGQALRKYRDHAGTVNCVKFNEESTVILSGSLDNTVRAWD 511
Score = 45.4 bits (106), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 24/104 (23%), Positives = 46/104 (44%)
Frame = +2
Query: 34 RLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLE 93
R T G D V LW+ ++ + + GH V + + I +G ++ ++D+
Sbjct: 212 RYCMTCGSDKSVKLWNPHRELFLKTYIGHGHEVLDAQGSGDNSQICSGGIDKTVVLFDVA 391
Query: 94 AAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRK 137
+ + LR H + + F+ + SGS D ++ WD R +
Sbjct: 392 SGQALRKYRDHAGTVNCVKFNEESTVILSGSLDNTVRAWDTRSR 523
>13278
Length = 870
Score = 64.3 bits (155), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 34/101 (33%), Positives = 56/101 (55%)
Frame = +1
Query: 120 VASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAG 179
+AS S D+ ++LW++ R C+ H + V + FSPDGK+LAS + D V +W++ G
Sbjct: 121 LASASFDSTVRLWEVERGLCLHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNVQTG 300
Query: 180 KMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEK 220
++ + G G V H + + AS +SD ++ DL K
Sbjct: 301 SLVHSYKGTGGIFEVCWNHRGDKVGAS-ASDGSVFVLDLRK 420
Score = 58.9 bits (141), Expect = 5e-09, Method: Compositional matrix adjust.
Identities = 38/139 (27%), Positives = 73/139 (52%), Gaps = 9/139 (6%)
Frame = +1
Query: 47 LWSINKPNCIMSLTGHTSPVESVRL--------NTPEELIVA-GSQSGSIRVWDLEAAKI 97
+WS+ K +CI L T + +++ N LI+A S ++R+W++E
Sbjct: 1 IWSMGKDSCIHDLQLTTKEIYTIKWSPTGPGTSNPNTSLILASASFDSTVRLWEVERGLC 180
Query: 98 LRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSP 157
L TL H+ + S+ F P G+++ASGS D + +W+++ V Y+G + + + ++
Sbjct: 181 LHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNVQTGSLVHSYKG-TGGIFEVCWNH 357
Query: 158 DGKWLASAADDHTVKLWDL 176
G + ++A D +V + DL
Sbjct: 358 RGDKVGASASDGSVFVLDL 414
Score = 57.8 bits (138), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 34/122 (27%), Positives = 60/122 (49%), Gaps = 9/122 (7%)
Frame = +1
Query: 131 LWDIRRKGCVFRYRGHSQAVRCLRFSPDGKW---------LASAADDHTVKLWDLTAGKM 181
+W + + C+ + ++ + +++SP G LASA+ D TV+LW++ G
Sbjct: 1 IWSMGKDSCIHDLQLTTKEIYTIKWSPTGPGTSNPNTSLILASASFDSTVRLWEVERGLC 180
Query: 182 MSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVLFNP 241
+ H PV V F P+ LASGS D+ + W+++ +V +G G + V +N
Sbjct: 181 LHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNVQTGSLVHSYKGT-GGIFEVCWNH 357
Query: 242 DG 243
G
Sbjct: 358 RG 363
Score = 43.1 bits (100), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 37/109 (33%), Positives = 54/109 (49%), Gaps = 2/109 (1%)
Frame = +1
Query: 198 HPNEYL-LASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVLFNPDGCCLYSGCQDSLRV 256
+PN L LAS S D T+R W++E+ + + PV SV F+PDG L SG D V
Sbjct: 100 NPNTSLILASASFDSTVRLWEVERGLCLHTLTKHQEPVYSVAFSPDGKYLASGSFDKC-V 276
Query: 257 YGWEPERCFDVVLVNWGKVADLAIC-NDQLIGVAFSQSNVSSYVVDLTR 304
+ W + +V G +C N + V S S+ S +V+DL +
Sbjct: 277 HIWNVQTG-SLVHSYKGTGGIFEVCWNHRGDKVGASASDGSVFVLDLRK 420
>16199
Length = 694
Score = 53.5 bits (127), Expect(2) = 1e-10, Method: Compositional matrix adjust.
Identities = 32/104 (30%), Positives = 53/104 (50%), Gaps = 1/104 (0%)
Frame = +1
Query: 117 GEFVASGSQDTNIKLWDIRR-KGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWD 175
G ++A+ ++D+ +KLWD+R+ K G V+ L F G +LA A D V+++
Sbjct: 232 GYYLATSAEDSVVKLWDLRKLKNFKTLQLGDKYEVKALCFDQSGTYLAVAGSD--VRVYL 405
Query: 176 LTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLE 219
++ F HT V F N +AS S DR+++F+ L
Sbjct: 406 CKQWNELAVFNDHTATATGVRFGTNANFIASASMDRSLKFFGLN 537
Score = 30.4 bits (67), Expect(2) = 1e-10, Method: Compositional matrix adjust.
Identities = 13/41 (31%), Positives = 23/41 (56%), Gaps = 1/41 (2%)
Frame = +2
Query: 74 PEELIVA-GSQSGSIRVWDLEAAKILRTLMGHKANICSLDF 113
P+ LI A G++ I++WDL+ + GH+ + S+ F
Sbjct: 101 PDGLIFATGTEDSVIKIWDLKERANVANFQGHQGPVTSISF 223
Score = 44.7 bits (104), Expect(2) = 7e-09, Method: Compositional matrix adjust.
Identities = 19/50 (38%), Positives = 30/50 (60%), Gaps = 1/50 (2%)
Frame = +2
Query: 113 FHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSP-DGKW 161
FHP G A+G++D+ IK+WD++ + V ++GH V + FS D W
Sbjct: 95 FHPDGLIFATGTEDSVIKIWDLKERANVANFQGHQGPVTSISFSETDTTW 244
Score = 33.5 bits (75), Expect(2) = 7e-09, Method: Compositional matrix adjust.
Identities = 26/102 (25%), Positives = 38/102 (37%), Gaps = 41/102 (40%)
Frame = +1
Query: 158 DGKWLASAADDHTVKLWDL------------------------------TAG-------- 179
+G +LA++A+D VKLWDL AG
Sbjct: 229 NGYYLATSAEDSVVKLWDLRKLKNFKTLQLGDKYEVKALCFDQSGTYLAVAGSDVRVYLC 408
Query: 180 ---KMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDL 218
++ F HT V F N +AS S DR+++F+ L
Sbjct: 409 KQWNELAVFNDHTATATGVRFGTNANFIASASMDRSLKFFGL 534
Score = 48.5 bits (114), Expect = 9e-06, Method: Compositional matrix adjust.
Identities = 19/49 (38%), Positives = 28/49 (57%)
Frame = +2
Query: 149 AVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEF 197
A+ C +F PDG A+ +D +K+WDL ++ F GH GPV + F
Sbjct: 77 ALTCAQFHPDGLIFATGTEDSVIKIWDLKERANVANFQGHQGPVTSISF 223
Score = 45.1 bits (105), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 23/78 (29%), Positives = 39/78 (50%), Gaps = 12/78 (15%)
Frame = +2
Query: 195 VEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVLFNPDGC-------CLY 247
+FHP+ + A+G+ D I+ WDL++ V+ +G GPV S+ F+ L+
Sbjct: 89 AQFHPDGLIFATGTEDSVIKIWDLKERANVANFQGHQGPVTSISFSETDTTWPRQQKTLW 268
Query: 248 SGCQD-----SLRVYGWE 260
S C + ++Y WE
Sbjct: 269 SNCGT*GN*RTSKLYSWE 322
Score = 36.6 bits (83), Expect = 0.036, Method: Compositional matrix adjust.
Identities = 29/105 (27%), Positives = 47/105 (44%), Gaps = 2/105 (1%)
Frame = +1
Query: 32 SGRLLATGGDDCRVNLWSINKPNCIMSLT-GHTSPVESVRLN-TPEELIVAGSQSGSIRV 89
+G LAT +D V LW + K +L G V+++ + + L VAGS +RV
Sbjct: 229 NGYYLATSAEDSVVKLWDLRKLKNFKTLQLGDKYEVKALCFDQSGTYLAVAGSD---VRV 399
Query: 90 WDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDI 134
+ + L H A + F F+AS S D ++K + +
Sbjct: 400 YLCKQWNELAVFNDHTATATGVRFGTNANFIASASMDRSLKFFGL 534
Score = 34.7 bits (78), Expect = 0.13, Method: Compositional matrix adjust.
Identities = 21/76 (27%), Positives = 37/76 (48%), Gaps = 1/76 (1%)
Frame = +1
Query: 183 SEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIE-GEPGPVRSVLFNP 241
+ PG G ++ N Y LA+ + D ++ WDL K + ++ G+ V+++ F+
Sbjct: 178 GQLPGPPGTRHLHLLL*NGYYLATSAEDSVVKLWDLRKLKNFKTLQLGDKYEVKALCFDQ 357
Query: 242 DGCCLYSGCQDSLRVY 257
G L D +RVY
Sbjct: 358 SGTYLAVAGSD-VRVY 402
Score = 31.6 bits (70), Expect = 0.94, Method: Compositional matrix adjust.
Identities = 11/40 (27%), Positives = 21/40 (52%)
Frame = +2
Query: 33 GRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLN 72
G + ATG +D + +W + + + + GH PV S+ +
Sbjct: 107 GLIFATGTEDSVIKIWDLKERANVANFQGHQGPVTSISFS 226
>03387
Length = 1891
Score = 63.5 bits (153), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 52/199 (26%), Positives = 86/199 (43%), Gaps = 15/199 (7%)
Frame = +1
Query: 78 IVAGSQSGSIRVWDLEAAK-------ILRTLMGHKANICSLDFHPYGE-FVASGSQDTNI 129
+++ S +I +WD+ + + GH + + + +H E S + D +
Sbjct: 409 LLSASDDHTICLWDINSTQRESRVVDAHTIFTGHTSVVEDVAWHLLHESLFGSVADDQKL 588
Query: 130 KLWDIRRKGCV---FRYRGHSQAVRCLRFSPDGKW-LASAADDHTVKLWDLTAGKM-MSE 184
+WD R H+ V CL F+P ++ LA+ + D TV LWDL K+ +
Sbjct: 589 MIWDTRSNTTSKPSHVVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHS 768
Query: 185 FPGHTGPVNVVEFHP-NEYLLASGSSDRTIRFWDLEKFQVVSCIE-GEPGPVRSVLFNPD 242
F H + V++ P NE +LAS +DR + WDL K E E GP P+
Sbjct: 769 FESHKDEIFQVQWSPHNETILASSGTDRRLHVWDLSKIGEEQLPEDAEDGP-------PE 927
Query: 243 GCCLYSGCQDSLRVYGWEP 261
++ G + + W P
Sbjct: 928 LLFIHGGHTAKISDFSWNP 984
Score = 59.3 bits (142), Expect = 5e-09, Method: Compositional matrix adjust.
Identities = 48/174 (27%), Positives = 81/174 (46%), Gaps = 14/174 (8%)
Frame = +1
Query: 101 LMGHKANICSLDFHP-YGEFVASGSQDTNIKLWDI---RRKGCVFR----YRGHSQAVRC 152
L GH+ L ++P + S S D I LWDI +R+ V + GH+ V
Sbjct: 349 LKGHQKEGYGLSWNPNLNGHLLSASDDHTICLWDINSTQRESRVVDAHTIFTGHTSVVED 528
Query: 153 LRFSPDGKWL-ASAADDHTVKLWDL---TAGKMMSEFPGHTGPVNVVEFHP-NEYLLASG 207
+ + + L S ADD + +WD T K HT VN + F+P +E++LA+G
Sbjct: 529 VAWHLLHESLFGSVADDQKLMIWDTRSNTTSKPSHVVDAHTAEVNCLSFNPYSEFILATG 708
Query: 208 SSDRTIRFWDLEKFQV-VSCIEGEPGPVRSVLFNPDGCCLYSGCQDSLRVYGWE 260
S+D+T+ WDL ++ + E + V ++P + + R++ W+
Sbjct: 709 SADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLHVWD 870
Score = 38.1 bits (87), Expect = 0.010, Method: Compositional matrix adjust.
Identities = 36/136 (26%), Positives = 58/136 (42%), Gaps = 17/136 (12%)
Frame = +1
Query: 16 IVAHASNVSSLVLGKASGRLLATGGDDCRVNLWSI-NKPNCIMSLTGHTSPVESVRLNTP 74
+ AH + V+ L S +LATG D V LW + N + S H + V+ +
Sbjct: 637 VDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPH 816
Query: 75 EELIVAGSQSG-SIRVWDLEA--------------AKILRTLMGHKANICSLDFHPYGEF 119
E I+A S + + VWDL ++L GH A I ++P +
Sbjct: 817 NETILASSGTDRRLHVWDLSKIGEEQLPEDAEDGPPELLFIHGGHTAKISDFSWNPNEPW 996
Query: 120 -VASGSQDTNIKLWDI 134
V S S+D +++W +
Sbjct: 997 IVCSVSEDNIMQVWQM 1044
>04088
Length = 511
Score = 63.2 bits (152), Expect = 3e-10, Method: Compositional matrix adjust.
Identities = 36/119 (30%), Positives = 65/119 (54%), Gaps = 3/119 (2%)
Frame = +3
Query: 148 QAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVE--FHPNEYLLA 205
+AV + F+ DG+ ++ D+TV+L D G+M++EF GH ++ + + L+
Sbjct: 33 KAVTSVTFTRDGQCSLVSSQDNTVRLMDKDTGEMLNEFTGHKHSQYKIDSCLNNEDTLVV 212
Query: 206 SGSSDRTIRFWDLEKFQVVSCIEGEPG-PVRSVLFNPDGCCLYSGCQDSLRVYGWEPER 263
SGS D + FWDL + ++V ++ + PV S+ F+ CL + C D +V+ W +
Sbjct: 213 SGSEDGKVYFWDLVEAKLVDTLDHKTTRPVHSLSFHHAELCLMTACAD--KVFLWRSSQ 383
Score = 36.6 bits (83), Expect = 0.036, Method: Compositional matrix adjust.
Identities = 19/72 (26%), Positives = 33/72 (45%), Gaps = 2/72 (2%)
Frame = +3
Query: 65 PVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLD--FHPYGEFVAS 122
V SV + + SQ ++R+ D + ++L GHK + +D + V S
Sbjct: 36 AVTSVTFTRDGQCSLVSSQDNTVRLMDKDTGEMLNEFTGHKHSQYKIDSCLNNEDTLVVS 215
Query: 123 GSQDTNIKLWDI 134
GS+D + WD+
Sbjct: 216 GSEDGKVYFWDL 251
>17266
Length = 480
Score = 62.8 bits (151), Expect = 5e-10, Method: Composition-based stats.
Identities = 39/147 (26%), Positives = 63/147 (42%), Gaps = 3/147 (2%)
Frame = -1
Query: 111 LDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHT 170
L P SG+ D + KLWD+R C + GH + + + P+G A+ +DD T
Sbjct: 441 LSLAPDMRTFVSGACDASAKLWDVRDGMCKQTFSGHESDINAITYFPNGHAFATGSDDAT 262
Query: 171 VKLWDLTAGKMMSEFPGHTG---PVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCI 227
+L+D+ A + + + H + V F + LL G D WD+ K + +
Sbjct: 261 CRLFDIRADQEIGMY-SHDNIICGITSVAFSKSGRLLLGGYDDFNCNIWDVLKQERTGVL 85
Query: 228 EGEPGPVRSVLFNPDGCCLYSGCQDSL 254
G V + DG + +G DS
Sbjct: 84 AGHDNRVSCLGVTEDGSAVATGSWDSF 4
Score = 62.0 bits (149), Expect = 7e-10, Method: Composition-based stats.
Identities = 36/135 (26%), Positives = 63/135 (46%), Gaps = 3/135 (2%)
Frame = -1
Query: 79 VAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKG 138
V+G+ S ++WD+ +T GH+++I ++ + P G A+GS D +L+DIR
Sbjct: 411 VSGACDASAKLWDVRDGMCKQTFSGHESDINAITYFPNGHAFATGSDDATCRLFDIRADQ 232
Query: 139 CVFRYRGHSQ---AVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVV 195
+ Y H + + FS G+ L DD +WD+ + GH V+ +
Sbjct: 231 EIGMY-SHDNIICGITSVAFSKSGRLLLGGYDDFNCNIWDVLKQERTGVLAGHDNRVSCL 55
Query: 196 EFHPNEYLLASGSSD 210
+ +A+GS D
Sbjct: 54 GVTEDGSAVATGSWD 10
Score = 60.5 bits (145), Expect = 2e-09, Method: Composition-based stats.
Identities = 37/115 (32%), Positives = 52/115 (45%), Gaps = 6/115 (5%)
Frame = -1
Query: 144 RGHSQAVR----CLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHP 199
R HSQA L +PD + S A D + KLWD+ G F GH +N + + P
Sbjct: 480 RRHSQATLGT**VLSLAPDMRTFVSGACDASAKLWDVRDGMCKQTFSGHESDINAITYFP 301
Query: 200 NEYLLASGSSDRTIRFWDLEKFQVVSCIEGEP--GPVRSVLFNPDGCCLYSGCQD 252
N + A+GS D T R +D+ Q + + + SV F+ G L G D
Sbjct: 300 NGHAFATGSDDATCRLFDIRADQEIGMYSHDNIICGITSVAFSKSGRLLLGGYDD 136
Score = 57.8 bits (138), Expect = 1e-08, Method: Composition-based stats.
Identities = 34/138 (24%), Positives = 58/138 (42%), Gaps = 3/138 (2%)
Frame = -1
Query: 34 RLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLE 93
R +G D LW + C + +GH S + ++ GS + R++D+
Sbjct: 420 RTFVSGACDASAKLWDVRDGMCKQTFSGHESDINAITYFPNGHAFATGSDDATCRLFDIR 241
Query: 94 AAKILRTLMGHKANIC---SLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAV 150
A + + + H IC S+ F G + G D N +WD+ ++ GH V
Sbjct: 240 ADQEI-GMYSHDNIICGITSVAFSKSGRLLLGGYDDFNCNIWDVLKQERTGVLAGHDNRV 64
Query: 151 RCLRFSPDGKWLASAADD 168
CL + DG +A+ + D
Sbjct: 63 SCLGVTEDGSAVATGSWD 10
Score = 36.6 bits (83), Expect = 0.034, Method: Composition-based stats.
Identities = 29/117 (24%), Positives = 49/117 (41%), Gaps = 3/117 (2%)
Frame = -1
Query: 14 QEIVAHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTS---PVESVR 70
Q H S+++++ +G ATG DD L+ I I + H + + SV
Sbjct: 351 QTFSGHESDINAITY-FPNGHAFATGSDDATCRLFDIRADQEI-GMYSHDNIICGITSVA 178
Query: 71 LNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDT 127
+ L++ G + +WD+ + L GH + L G VA+GS D+
Sbjct: 177 FSKSGRLLLGGYDDFNCNIWDVLKQERTGVLAGHDNRVSCLGVTEDGSAVATGSWDS 7
Score = 30.4 bits (67), Expect = 2.5, Method: Composition-based stats.
Identities = 12/60 (20%), Positives = 25/60 (41%)
Frame = -1
Query: 194 VVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVLFNPDGCCLYSGCQDS 253
V+ P+ SG+ D + + WD+ G + ++ + P+G +G D+
Sbjct: 444 VLSLAPDMRTFVSGACDASAKLWDVRDGMCKQTFSGHESDINAITYFPNGHAFATGSDDA 265
>01768
Length = 1424
Score = 59.7 bits (143), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 61/249 (24%), Positives = 110/249 (44%), Gaps = 37/249 (14%)
Frame = +3
Query: 52 KPNCIMSLTGHTSPVESVRLNTPEELIVAGSQS--GSIRVWDL----------EAA---- 95
KP + H V +R+ + I GS S GS+ V+D+ EAA
Sbjct: 480 KPELNLVTMQHNGGVNRLRVTDINDKIYTGSWSDKGSVYVYDITXQTAIVDDAEAAGKYD 659
Query: 96 ----KILRTLMGHKANICSLDFHPYGE-FVASGSQDTNIKLWDIRRKGCVFR---YRGHS 147
I+ T+ H ++D+ P + ++ +G I + G Y H+
Sbjct: 660 STQKSIVHTVTHHTTEGFAIDWSPAAKGWLVTGDCTGAIYISQPSSSGWTTEKSSYAAHT 839
Query: 148 QAVRCLRFSP-DGKWLASAADDHTVKLWDL----TAGKMMSEFPGHTGPVNVVEFHPNE- 201
+V +++SP +G AS + D T+++W+ + +++ H+ +NV+ ++P E
Sbjct: 840 DSVEDVQWSPNEGNVFASCSVDRTLRIWNTQQKPSKANVLTVPEAHSRDINVINWNPIEK 1019
Query: 202 YLLASGSSDRTIRFWDLEKFQ-----VVSCIEGEPGPVRSVLFNPDGCCLY--SGCQDSL 254
+LLASG D I+ WDL F+ + + PV S+ +NP + SG D +
Sbjct: 1020HLLASGGDDGIIKIWDLRMFRNKPVSAQASFKLHSQPVTSLEWNPQDSSVLAASGEDDQI 1199
Query: 255 RVYGWEPER 263
++ + ER
Sbjct: 1200TIWDFSVER 1226
Score = 41.2 bits (95), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 34/134 (25%), Positives = 60/134 (44%), Gaps = 22/134 (16%)
Frame = +3
Query: 18 AHASNVSSLVLGKASGRLLATGGDDCRVNLWSI----NKP-NCIMSLTGHTSPVESVRLN 72
AH+ +++ + LLA+GGDD + +W + NKP + S H+ PV S+ N
Sbjct: 972 AHSRDINVINWNPIEKHLLASGGDDGIIKIWDLRMFRNKPVSAQASFKLHSQPVTSLEWN 1151
Query: 73 TPEELIVAGS-QSGSIRVWDLEA--------------AKILRTLMGHKANICSLDFHPY- 116
+ ++A S + I +WD A++L G + +I + +HP
Sbjct: 1152 PQDSSVLAASGEDDQITIWDFSVERDEGEGEEELDVPAQLLFQHCG-QTDIKEVHWHPQL 1328
Query: 117 -GEFVASGSQDTNI 129
G +++ D NI
Sbjct: 1329 PGVLISTAKSDFNI 1370
>14555
Length = 627
Score = 40.0 bits (92), Expect(2) = 5e-09, Method: Composition-based stats.
Identities = 23/62 (37%), Positives = 34/62 (54%), Gaps = 2/62 (3%)
Frame = -2
Query: 103 GHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRC--LRFSPDGK 160
GH+A+I + F+P G+ A+GS D +L+D+R V YR S C + FS G+
Sbjct: 605 GHEADINCVRFYPSGDAFATGSDDATCRLFDLRADREVNCYRKESIIFGCNAVDFSVSGR 426
Query: 161 WL 162
L
Sbjct: 425 LL 420
Score = 38.9 bits (89), Expect(2) = 5e-09, Method: Compositional matrix adjust.
Identities = 18/55 (32%), Positives = 28/55 (50%)
Frame = -3
Query: 166 ADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEK 220
+D+TV +WD G + GH V+ + P+ L +GS D T+R W E+
Sbjct: 409 TNDYTVNVWDALKGMRSTILYGHDNRVSCLRISPDGTSLCTGSWDYTLRIWA*ER 245
Score = 43.5 bits (101), Expect(2) = 1e-07, Method: Composition-based stats.
Identities = 17/42 (40%), Positives = 25/42 (59%)
Frame = -2
Query: 139 CVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGK 180
CV + GH + C+RF P G A+ +DD T +L+DL A +
Sbjct: 623 CVQMFEGHEADINCVRFYPSGDAFATGSDDATCRLFDLRADR 498
Score = 30.4 bits (67), Expect(2) = 1e-07, Method: Compositional matrix adjust.
Identities = 18/57 (31%), Positives = 29/57 (50%), Gaps = 1/57 (1%)
Frame = -3
Query: 208 SSDRTIRFWDLEKFQVVSCIEGEPGPVRSVLFNPDGCCLYSGCQD-SLRVYGWEPER 263
++D T+ WD K + + G V + +PDG L +G D +LR++ E ER
Sbjct: 409 TNDYTVNVWDALKGMRSTILYGHDNRVSCLRISPDGTSLCTGSWDYTLRIWA*ERER 239
Score = 40.0 bits (92), Expect = 0.003, Method: Composition-based stats.
Identities = 22/60 (36%), Positives = 31/60 (51%)
Frame = -2
Query: 185 FPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVLFNPDGC 244
F GH +N V F+P+ A+GS D T R +DL + V+C E S++F GC
Sbjct: 611 FEGHEADINCVRFYPSGDAFATGSDDATCRLFDLRADREVNCYRKE-----SIIF---GC 456
Score = 38.1 bits (87), Expect = 0.012, Method: Compositional matrix adjust.
Identities = 17/51 (33%), Positives = 27/51 (52%)
Frame = -3
Query: 124 SQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLW 174
+ D + +WD + GH V CLR SPDG L + + D+T+++W
Sbjct: 409 TNDYTVNVWDALKGMRSTILYGHDNRVSCLRISPDGTSLCTGSWDYTLRIW 257
Score = 32.3 bits (72), Expect = 0.58, Method: Compositional matrix adjust.
Identities = 21/67 (31%), Positives = 33/67 (49%), Gaps = 2/67 (2%)
Frame = -3
Query: 86 SIRVWDLEAAKILRT--LMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRY 143
++ VWD A K +R+ L GH + L P G + +GS D +++W R+
Sbjct: 397 TVNVWD--ALKGMRSTILYGHDNRVSCLRISPDGTSLCTGSWDYTLRIWA*ERE------ 242
Query: 144 RGHSQAV 150
RGHS +
Sbjct: 241 RGHSSNI 221
Score = 28.5 bits (62), Expect = 9.9, Method: Compositional matrix adjust.
Identities = 19/68 (27%), Positives = 31/68 (45%)
Frame = -3
Query: 41 DDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRT 100
+D VN+W K L GH + V +R++ + GS ++R+W E +
Sbjct: 406 NDYTVNVWDALKGMRSTILYGHDNRVSCLRISPDGTSLCTGSWDYTLRIWA*ERER---- 239
Query: 101 LMGHKANI 108
GH +NI
Sbjct: 238 --GHSSNI 221
>11493
Length = 535
Score = 58.9 bits (141), Expect = 6e-09, Method: Compositional matrix adjust.
Identities = 42/167 (25%), Positives = 71/167 (42%), Gaps = 14/167 (8%)
Frame = -2
Query: 62 HTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLD--------- 112
H V +V ++ P + + G + G ++VWD+ G+K + LD
Sbjct: 480 HGEVVCAVTISNPTKYVYTGGK-GCVKVWDISQP-------GNKNPVSQLDCLQRDNYIR 325
Query: 113 ---FHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRC--LRFSPDGKWLASAAD 167
P G + G + +N+ +WD+ + S A C L SPD K S
Sbjct: 324 SVKLLPDGRTLIVGGEASNLSIWDLASPTPRIKAELTSAAPACYALAISPDSKVCFSCCS 145
Query: 168 DHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIR 214
D + +WDL ++ +F GHT + ++ P+ L +G D T+R
Sbjct: 144 DGNIAVWDLHNEILVRQFQGHTDGASCIDISPDGSRLWTGGLDNTVR 4
Score = 50.1 bits (118), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 36/163 (22%), Positives = 69/163 (42%), Gaps = 11/163 (6%)
Frame = -2
Query: 102 MGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKG---------CVFRYRGHSQAVRC 152
+ H +C++ ++V +G + +K+WDI + G C+ R +R
Sbjct: 486 LSHGEVVCAVTISNPTKYVYTGGKGC-VKVWDISQPGNKNPVSQLDCLQR----DNYIRS 322
Query: 153 LRFSPDGKWLASAADDHTVKLWDLTAG--KMMSEFPGHTGPVNVVEFHPNEYLLASGSSD 210
++ PDG+ L + + +WDL + ++ +E + P+ + S SD
Sbjct: 321 VKLLPDGRTLIVGGEASNLSIWDLASPTPRIKAELTSAAPACYALAISPDSKVCFSCCSD 142
Query: 211 RTIRFWDLEKFQVVSCIEGEPGPVRSVLFNPDGCCLYSGCQDS 253
I WDL +V +G + +PDG L++G D+
Sbjct: 141 GNIAVWDLHNEILVRQFQGHTDGASCIDISPDGSRLWTGGLDN 13
Score = 42.0 bits (97), Expect = 9e-04, Method: Compositional matrix adjust.
Identities = 23/100 (23%), Positives = 43/100 (43%), Gaps = 2/100 (2%)
Frame = -2
Query: 33 GRLLATGGDDCRVNLWSINKPN--CIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVW 90
GR L GG+ +++W + P LT ++ ++ ++ + G+I VW
Sbjct: 303 GRTLIVGGEASNLSIWDLASPTPRIKAELTSAAPACYALAISPDSKVCFSCCSDGNIAVW 124
Query: 91 DLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIK 130
DL ++R GH +D P G + +G D ++
Sbjct: 123 DLHNEILVRQFQGHTDGASCIDISPDGSRLWTGGLDNTVR 4
>02090
Length = 1841
Score = 58.9 bits (141), Expect = 6e-09, Method: Compositional matrix adjust.
Identities = 41/158 (25%), Positives = 70/158 (44%), Gaps = 12/158 (7%)
Frame = -3
Query: 39 GGDDCRVNLWSINKPN----------CIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIR 88
GG C V +W I++P C +++T + P R ++ ++
Sbjct: 1839 GGKGC-VKVWDISQPGTKAPCLNWIACNVTIT--SGPSSCCRTGAR*SW----REASTLS 1681
Query: 89 VWDLEAA--KILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGH 146
+WDL +I L +L P G+ S D NI +WD+ + V +++GH
Sbjct: 1680 IWDLATPTPRIKAELTSSAPACYALAISPDGKVCFSCCSDGNIAVWDLHNQTLVRQFQGH 1501
Query: 147 SQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSE 184
+ C+ SPDG L + D+TV+ WDL G+ + +
Sbjct: 1500 TDGASCIDISPDGTKLWTGGLDNTVRSWDLREGRQLQQ 1387
Score = 55.5 bits (132), Expect = 6e-08, Method: Compositional matrix adjust.
Identities = 37/186 (19%), Positives = 80/186 (43%)
Frame = -3
Query: 33 GRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDL 92
G++ + D + +W ++ + GHT + ++ + G ++R WDL
Sbjct: 1590 GKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISPDGTKLWTGGLDNTVRSWDL 1411
Query: 93 EAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRC 152
+ L+ + I SL + P GE++A G + +N+++ K ++ H V
Sbjct: 1410 REGRQLQQ-HDFSSQIFSLGYCPTGEWLAVGMESSNVEVLH-HSKPDKYQLHLHESCVLS 1237
Query: 153 LRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRT 212
L+F+ GKW S D+ + W G + + + V + ++ + +GS D+
Sbjct: 1236 LKFAYCGKWFVSTGKDNLLNAWRTPYGASIFQ-SKESSSVLSCDIAADDKYIVTGSGDKK 1060
Query: 213 IRFWDL 218
+++
Sbjct: 1059 ATLYEV 1042
Score = 52.4 bits (124), Expect = 5e-07, Method: Compositional matrix adjust.
Identities = 29/96 (30%), Positives = 46/96 (47%), Gaps = 2/96 (2%)
Frame = -3
Query: 127 TNIKLWDIRRKGCVFRYRGHSQAVRC--LRFSPDGKWLASAADDHTVKLWDLTAGKMMSE 184
+ + +WD+ + S A C L SPDGK S D + +WDL ++ +
Sbjct: 1692 STLSIWDLATPTPRIKAELTSSAPACYALAISPDGKVCFSCCSDGNIAVWDLHNQTLVRQ 1513
Query: 185 FPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEK 220
F GHT + ++ P+ L +G D T+R WDL +
Sbjct: 1512 FQGHTDGASCIDISPDGTKLWTGGLDNTVRSWDLRE 1405
Score = 32.0 bits (71), Expect = 0.71, Method: Compositional matrix adjust.
Identities = 31/135 (22%), Positives = 53/135 (39%), Gaps = 10/135 (7%)
Frame = -3
Query: 129 IKLWDIRRKG----CVFRYRGH----SQAVRCLRFSPDGKWLASAADDHTVKLWDLTAG- 179
+K+WDI + G C+ + S C R W ++ T+ +WDL
Sbjct: 1824 VKVWDISQPGTKAPCLNWIACNVTITSGPSSCCRTGAR*SWREAS----TLSIWDLATPT 1657
Query: 180 -KMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVL 238
++ +E + P+ + S SD I WDL +V +G +
Sbjct: 1656 PRIKAELTSSAPACYALAISPDGKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCID 1477
Query: 239 FNPDGCCLYSGCQDS 253
+PDG L++G D+
Sbjct: 1476 ISPDGTKLWTGGLDN 1432
>27270
Length = 1078
Score = 57.0 bits (136), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 40/174 (22%), Positives = 76/174 (43%), Gaps = 20/174 (11%)
Frame = +2
Query: 77 LIVAGSQSGSIRVWDLEAAKILRTL-MGHKANICSLDFHPYGEFVASGSQDTNIKLWDIR 135
++ GS GS+ ++ +E L GH + + + G + S S D ++ W++
Sbjct: 185 VVAVGSADGSVGLYSVETHTYTHMLNKGHSKAVTDMCWRADGRTLYSSSLDGHVIGWNVN 364
Query: 136 RKGCVFRYR---GHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPV 192
+ +++ G V C+ + L + DHT+K+WDLT ++ EF GH+ V
Sbjct: 365 TLHMIEKWKATSGRHHGVHCVCLCSSSRLLTA---DHTIKMWDLTTKNVLQEFSGHSTEV 535
Query: 193 --------------NVVEFHPNEYLLASGSSDRTIRFW--DLEKFQVVSCIEGE 230
++ + + Y+ ++ ++DRTI W D E Q + E
Sbjct: 536 IKLLPVLKPSSEQNDIGDSNLACYVFSAAAADRTINVWRCDSESSQATAVTSFE 697
>15118
Length = 1074
Score = 56.2 bits (134), Expect = 4e-08, Method: Compositional matrix adjust.
Identities = 40/174 (22%), Positives = 69/174 (39%), Gaps = 3/174 (1%)
Frame = +3
Query: 46 NLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDL---EAAKILRTLM 102
NL S H S V V + L++ I+ W + A++L +
Sbjct: 141 NLQSGKHRGSFGDTVAHVSGVRGVAFDAFNCLLITAGGDCDIKFWRFGSRDRARVLLKEL 320
Query: 103 GHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWL 162
I + H +A +D + + D+ V + GHS ++ L FS DG+WL
Sbjct: 321 KMSEGISRILLHRDSNMLAVVLEDFTVSVIDVDTLRVVRVFSGHSNSITDLSFSGDGRWL 500
Query: 163 ASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFW 216
+A+ D TV+ W L G+++ F ++ ++L S D + W
Sbjct: 501 ITASMDCTVRTWSLVHGRLIDCFAVEAAVTSLTMSPSQDFLATSHVGDVGVYLW 662
Score = 55.1 bits (131), Expect = 9e-08, Method: Compositional matrix adjust.
Identities = 42/211 (19%), Positives = 90/211 (42%), Gaps = 6/211 (2%)
Frame = +3
Query: 64 SPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTL---MGHKANICSLDFHPYGEFV 120
+ ++V +++ + G SG + +++L++ K + + H + + + F + +
Sbjct: 60 TTAQAVDISSCGNYVAVGYSSGHLDIYNLQSGKHRGSFGDTVAHVSGVRGVAFDAFNCLL 239
Query: 121 ASGSQDTNIKLWDI---RRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLT 177
+ D +IK W R + + S+ + + D LA +D TV + D+
Sbjct: 240 ITAGGDCDIKFWRFGSRDRARVLLKELKMSEGISRILLHRDSNMLAVVLEDFTVSVIDVD 419
Query: 178 AGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSV 237
+++ F GH+ + + F + L + S D T+R W L +++ C E V S+
Sbjct: 420 TLRVVRVFSGHSNSITDLSFSGDGRWLITASMDCTVRTWSLVHGRLIDCFAVEA-AVTSL 596
Query: 238 LFNPDGCCLYSGCQDSLRVYGWEPERCFDVV 268
+P L + + VY W + + V
Sbjct: 597 TMSPSQDFLATSHVGDVGVYLWANQTLYXFV 689
Score = 49.3 bits (116), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 40/166 (24%), Positives = 70/166 (42%), Gaps = 4/166 (2%)
Frame = +3
Query: 13 LQEIVAHASNVSSLVLGKASGRLLATGGDDCRVNLW---SINKPNCIMSLTGHTSPVESV 69
+ VAH S V + A LL T G DC + W S ++ ++ + + +
Sbjct: 171 FGDTVAHVSGVRGVAF-DAFNCLLITAGGDCDIKFWRFGSRDRARVLLKELKMSEGISRI 347
Query: 70 RLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNI 129
L+ ++ + ++ V D++ +++R GH +I L F G ++ + S D +
Sbjct: 348 LLHRDSNMLAVVLEDFTVSVIDVDTLRVVRVFSGHSNSITDLSFSGDGRWLITASMDCTV 527
Query: 130 KLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLA-SAADDHTVKLW 174
+ W + G + AV L SP +LA S D V LW
Sbjct: 528 RTWSLVH-GRLIDCFAVEAAVTSLTMSPSQDFLATSHVGDVGVYLW 662
>01462
Length = 995
Score = 55.5 bits (132), Expect = 6e-08, Method: Compositional matrix adjust.
Identities = 46/177 (25%), Positives = 76/177 (42%), Gaps = 11/177 (6%)
Frame = +2
Query: 78 IVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRK 137
+ AG+ I VWD+EA + L + GHK I + + S S+D +++WDIR
Sbjct: 242 LYAGAGDRKIHVWDIEAGQYLNAMEGHKDYIHKVVMKNDAQECVSASEDGTVRMWDIRSS 421
Query: 138 G----CVFRYRGH-------SQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFP 186
C+ + + +RCL P+ WL + W L + F
Sbjct: 422 TETVHCLEPSKNELCSRPLLGKWLRCLALDPEEGWLVCGGGP-KLSAWHLRTLAPTTIFD 598
Query: 187 GHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVLFNPDG 243
+ NV FH +E++L++G+S + W L+ + S I P V S+ N +
Sbjct: 599 TPSVSQNVALFH-DEFILSAGTSP-VMNHWRLDG-TLHSSIPCTPSSVFSLAINTNA 760
>18981
Length = 407
Score = 55.5 bits (132), Expect = 7e-08, Method: Composition-based stats.
Identities = 33/130 (25%), Positives = 66/130 (50%), Gaps = 1/130 (0%)
Frame = -2
Query: 114 HPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKL 173
H + S + D +++W ++ + RGH+ V C+ G+ + S + D T+ +
Sbjct: 397 HLLDNMIISAATDRTLRVWCLKNTCLLHTLRGHNDDVECVCIY--GRRVVSGSWDKTLIV 224
Query: 174 WDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQ-VVSCIEGEPG 232
W++ G+ + + GHT + V+F +E SGS+D +R W L+ Q +++ G+
Sbjct: 223 WEVDTGRPVHQLHGHTEAITAVQF--DEGKAVSGSADGDVRTWALDTGQCLLTMTTGQDI 50
Query: 233 PVRSVLFNPD 242
V V++N +
Sbjct: 49 EVYCVVYNQE 20
Score = 54.7 bits (130), Expect = 1e-07, Method: Composition-based stats.
Identities = 31/108 (28%), Positives = 60/108 (55%)
Frame = -2
Query: 75 EELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDI 134
+ +I++ + ++RVW L+ +L TL GH ++ + YG V SGS D + +W++
Sbjct: 388 DNMIISAATDRTLRVWCLKNTCLLHTLRGHNDDVECVCI--YGRRVVSGSWDKTLIVWEV 215
Query: 135 RRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMM 182
V + GH++A+ ++F +GK ++ +AD V+ W L G+ +
Sbjct: 214 DTGRPVHQLHGHTEAITAVQFD-EGKAVSGSADG-DVRTWALDTGQCL 77
Score = 39.7 bits (91), Expect = 0.004, Method: Composition-based stats.
Identities = 20/69 (28%), Positives = 36/69 (52%)
Frame = -2
Query: 33 GRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDL 92
GR + +G D + +W ++ + L GHT + +V+ + E V+GS G +R W L
Sbjct: 268 GRRVVSGSWDKTLIVWEVDTGRPVHQLHGHTEAITAVQFD--EGKAVSGSADGDVRTWAL 95
Query: 93 EAAKILRTL 101
+ + L T+
Sbjct: 94 DTGQCLLTM 68
>15780
Length = 735
Score = 54.7 bits (130), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 24/61 (39%), Positives = 37/61 (60%)
Frame = -1
Query: 160 KWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLE 219
K+L++A DHTV +WD+ +G ++ HT V + F + +LASG D +IR WDL
Sbjct: 735 KYLSTAGADHTVIVWDIASGTAVAHLTAHTDTVYALCFSRDGTVLASGGMDNSIRLWDLA 556
Query: 220 K 220
+
Sbjct: 555 R 553
Score = 46.2 bits (108), Expect = 4e-05, Method: Compositional matrix adjust.
Identities = 22/67 (32%), Positives = 36/67 (53%)
Frame = -1
Query: 118 EFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLT 177
+++++ D + +WDI V H+ V L FS DG LAS D++++LWDL
Sbjct: 735 KYLSTAGADHTVIVWDIASGTAVAHLTAHTDTVYALCFSRDGTVLASGGMDNSIRLWDL- 559
Query: 178 AGKMMSE 184
++M E
Sbjct: 558 -ARVMEE 541
Score = 40.4 bits (93), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 19/59 (32%), Positives = 30/59 (50%)
Frame = -1
Query: 34 RLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDL 92
+ L+T G D V +W I + LT HT V ++ + ++ +G SIR+WDL
Sbjct: 735 KYLSTAGADHTVIVWDIASGTAVAHLTAHTDTVYALCFSRDGTVLASGGMDNSIRLWDL 559
Score = 40.0 bits (92), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 17/51 (33%), Positives = 28/51 (54%)
Frame = -1
Query: 86 SIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRR 136
++ VWD+ + + L H + +L F G +ASG D +I+LWD+ R
Sbjct: 705 TVIVWDIASGTAVAHLTAHTDTVYALCFSRDGTVLASGGMDNSIRLWDLAR 553
>01249
Length = 1743
Score = 54.7 bits (130), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 38/155 (24%), Positives = 74/155 (47%), Gaps = 17/155 (10%)
Frame = -1
Query: 58 SLTGHTSPVESVRLN--TPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHP 115
++ H+ P+ + + P + + S G+ ++WD+ + +LRT++ ++ + L
Sbjct: 1227 TINAHSEPITGLHVGCGGPAARVASSSSDGTCKLWDMLSGALLRTMV-YETGVGCLIMDK 1051
Query: 116 YGEFVASGSQDTNI---KLWDIRRKGCVFRYR-----------GHSQAVRCLRFSPDGKW 161
F+ +G + +I L+ + VF + GHS AV CL FS DG+
Sbjct: 1050 QEHFLLAGLDNGDILCSPLFGQISQSEVFVSKHTTKAGERVLQGHSDAVTCLAFSSDGQR 871
Query: 162 LASAADDHTVKLWDLTAGKMMS-EFPGHTGPVNVV 195
LAS + + V +W++ +G S + G G V ++
Sbjct: 870 LASGSQNGKVIIWNMESGDSTSLDISGAVGNVMII 766
Score = 43.9 bits (102), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 55/240 (22%), Positives = 93/240 (38%), Gaps = 27/240 (11%)
Frame = -1
Query: 68 SVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDT 127
SV + +P+ L S S I +W++ ++ L+ + F G +
Sbjct: 1479 SVLVVSPDGLFCLASISEKIYIWEMTGGSLV-GLLSDFNEATKIQFTDDGSQFVVATSSG 1303
Query: 128 NIKLWDIRR--KGCVFRYRG---------HSQAVRCLRFSPDG--KWLASAADDHTVKLW 174
++ +WD R R RG HS+ + L G +AS++ D T KLW
Sbjct: 1302 HLNIWDFARVVTTTSQRARGLKPGRTINAHSEPITGLHVGCGGPAARVASSSSDGTCKLW 1123
Query: 175 DLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTI----RFWDLEKFQVV------ 224
D+ +G ++ TG V + E+ L +G + I F + + +V
Sbjct: 1122 DMLSGALLRTMVYETG-VGCLIMDKQEHFLLAGLDNGDILCSPLFGQISQSEVFVSKHTT 946
Query: 225 ----SCIEGEPGPVRSVLFNPDGCCLYSGCQDSLRVYGWEPERCFDVVLVNWGKVADLAI 280
++G V + F+ DG L SG Q+ +V W E L G V ++ I
Sbjct: 945 KAGERVLQGHSDAVTCLAFSSDGQRLASGSQNG-KVIIWNMESGDSTSLDISGAVGNVMI 769
>21105
Length = 650
Score = 54.3 bits (129), Expect = 2e-07, Method: Composition-based stats.
Identities = 27/102 (26%), Positives = 51/102 (50%), Gaps = 4/102 (3%)
Frame = +1
Query: 77 LIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRR 136
+ + + IR +D K++ ++ H ++ SL P G ++ SGS D +I+LW++
Sbjct: 106 ITITAHEDRHIRFFDNNTGKLIHAMVAHLDSVTSLAVDPNGLYLLSGSHDCSIRLWNLDS 285
Query: 137 KGCVFRYRGH----SQAVRCLRFSPDGKWLASAADDHTVKLW 174
K CV H +++ + F P ++ASA D K++
Sbjct: 286 KTCVQEITSHRKKFDESIHDVAFHPQKPYIASAGADALAKVF 411
Score = 45.8 bits (107), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 25/101 (24%), Positives = 46/101 (45%), Gaps = 4/101 (3%)
Frame = +1
Query: 114 HPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKL 173
HP + +D +I+ +D + H +V L P+G +L S + D +++L
Sbjct: 91 HPTMPITITAHEDRHIRFFDNNTGKLIHAMVAHLDSVTSLAVDPNGLYLLSGSHDCSIRL 270
Query: 174 WDLTAGKMMSEFPGHTG----PVNVVEFHPNEYLLASGSSD 210
W+L + + E H ++ V FHP + +AS +D
Sbjct: 271 WNLDSKTCVQEITSHRKKFDESIHDVAFHPQKPYIASAGAD 393
Score = 43.5 bits (101), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 23/99 (23%), Positives = 48/99 (48%), Gaps = 4/99 (4%)
Frame = +1
Query: 38 TGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKI 97
T +D + + N I ++ H V S+ ++ +++GS SIR+W+L++
Sbjct: 115 TAHEDRHIRFFDNNTGKLIHAMVAHLDSVTSLAVDPNGLYLLSGSHDCSIRLWNLDSKTC 294
Query: 98 LRTLMGHKA----NICSLDFHPYGEFVASGSQDTNIKLW 132
++ + H+ +I + FHP ++AS D K++
Sbjct: 295 VQEITSHRKKFDESIHDVAFHPQKPYIASAGADALAKVF 411
Score = 41.6 bits (96), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 26/95 (27%), Positives = 41/95 (43%), Gaps = 4/95 (4%)
Frame = +1
Query: 164 SAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQV 223
+A +D ++ +D GK++ H V + PN L SGS D +IR W+L+
Sbjct: 115 TAHEDRHIRFFDNNTGKLIHAMVAHLDSVTSLAVDPNGLYLLSGSHDCSIRLWNLDSKTC 294
Query: 224 VSCIEGE----PGPVRSVLFNPDGCCLYSGCQDSL 254
V I + V F+P + S D+L
Sbjct: 295 VQEITSHRKKFDESIHDVAFHPQKPYIASAGADAL 399
Score = 39.7 bits (91), Expect = 0.004, Method: Composition-based stats.
Identities = 16/50 (32%), Positives = 29/50 (58%)
Frame = +1
Query: 13 LQEIVAHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGH 62
+ +VAH +V+SL + +G L +G DC + LW+++ C+ +T H
Sbjct: 169 IHAMVAHLDSVTSLAV-DPNGLYLLSGSHDCSIRLWNLDSKTCVQEITSH 315
Score = 35.4 bits (80), Expect = 0.068, Method: Composition-based stats.
Identities = 23/88 (26%), Positives = 41/88 (46%), Gaps = 1/88 (1%)
Frame = +1
Query: 178 AGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSV 237
AG+ +S P + HP + + DR IRF+D +++ + V S+
Sbjct: 31 AGRTLSM*YKWQQPDQLHHQHPTMPITITAHEDRHIRFFDNNTGKLIHAMVAHLDSVTSL 210
Query: 238 LFNPDGCCLYSGCQD-SLRVYGWEPERC 264
+P+G L SG D S+R++ + + C
Sbjct: 211 AVDPNGLYLLSGSHDCSIRLWNLDSKTC 294
>26939
Length = 388
Score = 53.9 bits (128), Expect = 2e-07, Method: Composition-based stats.
Identities = 23/58 (39%), Positives = 35/58 (60%)
Frame = +2
Query: 78 IVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIR 135
+V+ S +IRVWDL + ++TL H+ S+DFH +V SGS D +K+W+ R
Sbjct: 11 LVSASDDKTIRVWDLRNKRCMKTLYAHQHFCTSIDFHKAHPYVISGSVDQTVKVWECR 184
Score = 50.8 bits (120), Expect = 2e-06, Method: Composition-based stats.
Identities = 21/59 (35%), Positives = 34/59 (57%)
Frame = +2
Query: 159 GKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWD 217
GK+L SA+DD T+++WDL + M H ++FH + SGS D+T++ W+
Sbjct: 2 GKYLVSASDDKTIRVWDLRNKRCMKTLYAHQHFCTSIDFHKAHPYVISGSVDQTVKVWE 178
Score = 43.5 bits (101), Expect = 3e-04, Method: Composition-based stats.
Identities = 18/59 (30%), Positives = 31/59 (52%)
Frame = +2
Query: 117 GEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWD 175
G+++ S S D I++WD+R K C+ H + F ++ S + D TVK+W+
Sbjct: 2 GKYLVSASDDKTIRVWDLRNKRCMKTLYAHQHFCTSIDFHKAHPYVISGSVDQTVKVWE 178
>37180
Length = 681
Score = 51.6 bits (122), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 25/77 (32%), Positives = 40/77 (51%), Gaps = 1/77 (1%)
Frame = +1
Query: 101 LMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFR-YRGHSQAVRCLRFSPDG 159
L GH + + HP V + S+D +LWD R + ++GH+Q V F+ G
Sbjct: 7 LNGHDQELSDVHAHPTQRLVVTSSKDMTFRLWDFRDSALLVNVFQGHTQPVTSAVFAS-G 183
Query: 160 KWLASAADDHTVKLWDL 176
+ S +DD TV++WD+
Sbjct: 184 DKVVSGSDDRTVRVWDM 234
Score = 50.1 bits (118), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 29/97 (29%), Positives = 50/97 (51%), Gaps = 2/97 (2%)
Frame = +1
Query: 145 GHSQAVRCLRFSPDGKWLASAADDHTVKLWDL-TAGKMMSEFPGHTGPVNVVEFHPNEYL 203
GH Q + + P + + +++ D T +LWD + +++ F GHT PV F + +
Sbjct: 13 GHDQELSDVHAHPTQRLVVTSSKDMTFRLWDFRDSALLVNVFQGHTQPVTSAVFASGDKV 192
Query: 204 LASGSSDRTIRFWDLEKFQV-VSCIEGEPGPVRSVLF 239
+ SGS DRT+R WD+ + ++ I + R V F
Sbjct: 193 V-SGSDDRTVRVWDMRNMRSPIATIRTDSAVNRFV*F 300
Score = 47.4 bits (111), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 24/78 (30%), Positives = 40/78 (51%), Gaps = 1/78 (1%)
Frame = +1
Query: 59 LTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLE-AAKILRTLMGHKANICSLDFHPYG 117
L GH + V + + L+V S+ + R+WD +A ++ GH + S F G
Sbjct: 7 LNGHDQELSDVHAHPTQRLVVTSSKDMTFRLWDFRDSALLVNVFQGHTQPVTSAVF-ASG 183
Query: 118 EFVASGSQDTNIKLWDIR 135
+ V SGS D +++WD+R
Sbjct: 184 DKVVSGSDDRTVRVWDMR 237
Score = 40.8 bits (94), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 24/73 (32%), Positives = 38/73 (52%), Gaps = 2/73 (2%)
Frame = +1
Query: 187 GHTGPVNVVEFHPNEYLLASGSSDRTIRFWDL-EKFQVVSCIEGEPGPVRSVLFNPDGCC 245
GH ++ V HP + L+ + S D T R WD + +V+ +G PV S +F G
Sbjct: 13 GHDQELSDVHAHPTQRLVVTSSKDMTFRLWDFRDSALLVNVFQGHTQPVTSAVF-ASGDK 189
Query: 246 LYSGCQD-SLRVY 257
+ SG D ++RV+
Sbjct: 190 VVSGSDDRTVRVW 228
>31864
Length = 545
Score = 49.7 bits (117), Expect = 4e-06, Method: Composition-based stats.
Identities = 39/140 (27%), Positives = 56/140 (40%), Gaps = 15/140 (10%)
Frame = +2
Query: 90 WDL-EAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQ 148
WD+ + K++ + + H I + G + S+DT KL+D C+ Y+ +
Sbjct: 2 WDVRKGQKVVDSGVDHTGGINDMQLSKDGTMFVTASKDTTAKLFDSESLMCLKTYKTE-R 178
Query: 149 AVRCLRFSP--DGKWLASAADDHTVKLWDLTAGKMMSEF------------PGHTGPVNV 194
V SP D L D V AGK S F GH GP+N
Sbjct: 179 PVNSAAISPILDHVVLGGGQDAMEVTTTSTKAGKFDSRFFHLIYEEEFARLKGHFGPINS 358
Query: 195 VEFHPNEYLLASGSSDRTIR 214
+ FHP+ ASG D +R
Sbjct: 359 LAFHPDGKSYASGGEDGFVR 418
Score = 43.5 bits (101), Expect = 2e-04, Method: Composition-based stats.
Identities = 34/138 (24%), Positives = 59/138 (42%), Gaps = 15/138 (10%)
Frame = +2
Query: 132 WDIRR-KGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTG 190
WD+R+ + V H+ + ++ S DG +A+ D T KL+D + + +
Sbjct: 2 WDVRKGQKVVDSGVDHTGGINDMQLSKDGTMFVTASKDTTAKLFDSESLMCLKTYKTER- 178
Query: 191 PVNVVEFHP--NEYLLASGSSDRTI------------RFWDLEKFQVVSCIEGEPGPVRS 236
PVN P + +L G + RF+ L + + ++G GP+ S
Sbjct: 179 PVNSAAISPILDHVVLGGGQDAMEVTTTSTKAGKFDSRFFHLIYEEEFARLKGHFGPINS 358
Query: 237 VLFNPDGCCLYSGCQDSL 254
+ F+PDG SG +D
Sbjct: 359 LAFHPDGKSYASGGEDGF 412
Score = 36.2 bits (82), Expect = 0.040, Method: Composition-based stats.
Identities = 34/141 (24%), Positives = 59/141 (41%), Gaps = 15/141 (10%)
Frame = +2
Query: 48 WSINKPNCIM-SLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKA 106
W + K ++ S HT + ++L+ + V S+ + +++D E+ L+T +
Sbjct: 2 WDVRKGQKVVDSGVDHTGGINDMQLSKDGTMFVTASKDTTAKLFDSESLMCLKTYKTERP 181
Query: 107 NICSLDFHP-YGEFVASGSQD--------TNIKLWDIRRKGCVF-----RYRGHSQAVRC 152
+ S P V G QD T +D R ++ R +GH +
Sbjct: 182 -VNSAAISPILDHVVLGGGQDAMEVTTTSTKAGKFDSRFFHLIYEEEFARLKGHFGPINS 358
Query: 153 LRFSPDGKWLASAADDHTVKL 173
L F PDGK AS +D V++
Sbjct: 359 LAFHPDGKSYASGGEDGFVRV 421
>19863
Length = 502
Score = 49.7 bits (117), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 23/63 (36%), Positives = 35/63 (55%)
Frame = +1
Query: 158 DGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWD 217
DG L S + D ++ +WD+ G GH G VN V F ++ L S S+D T+R W+
Sbjct: 4 DGLQLVSGSSDMSIVVWDVENGVQKLRLQGHAGWVNDVHFSQDQCWLLSCSNDNTVRIWN 183
Query: 218 LEK 220
+E+
Sbjct: 184 IEE 192
Score = 47.8 bits (112), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 22/60 (36%), Positives = 36/60 (60%)
Frame = +1
Query: 117 GEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDL 176
G + SGS D +I +WD+ R +GH+ V + FS D WL S ++D+TV++W++
Sbjct: 7 GLQLVSGSSDMSIVVWDVENGVQKLRLQGHAGWVNDVHFSQDQCWLLSCSNDNTVRIWNI 186
Score = 37.4 bits (85), Expect = 0.017, Method: Compositional matrix adjust.
Identities = 17/73 (23%), Positives = 35/73 (47%)
Frame = +1
Query: 33 GRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDL 92
G L +G D + +W + + L GH V V + + +++ S ++R+W++
Sbjct: 7 GLQLVSGSSDMSIVVWDVENGVQKLRLQGHAGWVNDVHFSQDQCWLLSCSNDNTVRIWNI 186
Query: 93 EAAKILRTLMGHK 105
E + + +M HK
Sbjct: 187 EESDQIPIVMEHK 225
Score = 36.6 bits (83), Expect = 0.033, Method: Compositional matrix adjust.
Identities = 29/96 (30%), Positives = 45/96 (46%), Gaps = 1/96 (1%)
Frame = +1
Query: 204 LASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVLFNPDGCCLYSGCQD-SLRVYGWEPE 262
L SGSSD +I WD+E ++G G V V F+ D C L S D ++R++ E
Sbjct: 16 LVSGSSDMSIVVWDVENGVQKLRLQGHAGWVNDVHFSQDQCWLLSCSNDNTVRIWNIEES 195
Query: 263 RCFDVVLVNWGKVADLAICNDQLIGVAFSQSNVSSY 298
+V+ + + L + G FS S V ++
Sbjct: 196 DQIPIVMEH-KRAQGLKVTKCSKCGKPFSMSEVENF 300
>00825
Length = 1821
Score = 48.9 bits (115), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 34/142 (23%), Positives = 62/142 (43%), Gaps = 3/142 (2%)
Frame = -2
Query: 80 AGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGC 139
+G+ G + W+L ++ + H + + H G++ S D IK W + +G
Sbjct: 1820 SGACDGELICWNLPKQQMACRVQAHDGIVHGMAAHSSGQYFFSCGSDKTIKQWSLDPEGT 1641
Query: 140 VFRYRGHSQAVRCLRFSPDGKWLAS--AADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEF 197
+ ++ +C+ S D W V +WD + M F V+ V+F
Sbjct: 1640 IAPEPVNTLLAKCIYTSLDHHWKDDIFVTSGSRVDVWDEKRSEPMRSFSWGVESVHHVKF 1461
Query: 198 HPNE-YLLASGSSDRTIRFWDL 218
+P E YLL + + DR+I +D+
Sbjct: 1460 NPVETYLLGAAAHDRSILLYDM 1395
Score = 33.5 bits (75), Expect = 0.24, Method: Compositional matrix adjust.
Identities = 30/120 (25%), Positives = 51/120 (42%), Gaps = 10/120 (8%)
Frame = -2
Query: 164 SAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQV 223
S A D + W+L +M H G V+ + H + S SD+TI+ W L+
Sbjct: 1820 SGACDGELICWNLPKQQMACRVQAHDGIVHGMAAHSSGQYFFSCGSDKTIKQWSLDPEGT 1641
Query: 224 VSCIEGEPGPVRSVLFNPDGCCLYSGC----QDSL------RVYGWEPERCFDVVLVNWG 273
++ P PV ++L C+Y+ +D + RV W+ +R + +WG
Sbjct: 1640 IA-----PEPVNTLL----AKCIYTSLDHHWKDDIFVTSGSRVDVWDEKRSEPMRSFSWG 1488
>15337
Length = 860
Score = 48.5 bits (114), Expect = 9e-06, Method: Compositional matrix adjust.
Identities = 25/101 (24%), Positives = 50/101 (49%)
Frame = -1
Query: 97 ILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFS 156
+ R ++G A I F P ++A QD ++++++ + + + + C+ +S
Sbjct: 350 LYRWVVGTGA-ISEFAFSPCSRYLAVVGQDGHLRVFNYNSMELIGTMKSYFGGLLCVCWS 174
Query: 157 PDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEF 197
PDGK++ + +D V +W +++ GH VNVV F
Sbjct: 173 PDGKYIVTGGEDDLVTVWSFHEKRVVCRGHGHKSWVNVVAF 51
Score = 33.9 bits (76), Expect = 0.24, Method: Compositional matrix adjust.
Identities = 23/104 (22%), Positives = 42/104 (40%), Gaps = 2/104 (1%)
Frame = -1
Query: 13 LQEIVAHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLN 72
L V +S S R LA G D + +++ N I ++ + + V +
Sbjct: 350 LYRWVVGTGAISEFAFSPCS-RYLAVVGQDGHLRVFNYNSMELIGTMKSYFGGLLCVCWS 174
Query: 73 TPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKA--NICSLDFH 114
+ IV G + + VW +++ GHK+ N+ + D H
Sbjct: 173 PDGKYIVTGGEDDLVTVWSFHEKRVVCRGHGHKSWVNVVAFDIH 42
>27806
Length = 419
Score = 48.5 bits (114), Expect = 9e-06, Method: Compositional matrix adjust.
Identities = 19/55 (34%), Positives = 31/55 (56%)
Frame = -1
Query: 162 LASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFW 216
+ +A+ DHT +++ + G + + GH G VN V FHP + L+ + S D T W
Sbjct: 380 IGTASADHTARIYSIETGACVLTYGGHQGSVNAVRFHPGQDLVLTASGDHTAHVW 216
Score = 45.1 bits (105), Expect = 8e-05, Method: Compositional matrix adjust.
Identities = 19/61 (31%), Positives = 30/61 (49%)
Frame = -1
Query: 114 HPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKL 173
HP + + S D +++ I CV Y GH +V +RF P + +A+ DHT +
Sbjct: 389 HP---IIGTASADHTARIYSIETGACVLTYGGHQGSVNAVRFHPGQDLVLTASGDHTAHV 219
Query: 174 W 174
W
Sbjct: 218 W 216
Score = 35.4 bits (80), Expect = 0.068, Method: Compositional matrix adjust.
Identities = 14/56 (25%), Positives = 28/56 (50%)
Frame = -1
Query: 35 LLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVW 90
++ T D ++SI C+++ GH V +VR + ++L++ S + VW
Sbjct: 383 IIGTASADHTARIYSIETGACVLTYGGHQGSVNAVRFHPGQDLVLTASGDHTAHVW 216
Score = 33.9 bits (76), Expect = 0.19, Method: Compositional matrix adjust.
Identities = 14/56 (25%), Positives = 28/56 (50%)
Frame = -1
Query: 77 LIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLW 132
+I S + R++ +E + T GH+ ++ ++ FHP + V + S D +W
Sbjct: 383 IIGTASADHTARIYSIETGACVLTYGGHQGSVNAVRFHPGQDLVLTASGDHTAHVW 216
>26107
Length = 1338
Score = 47.4 bits (111), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 37/151 (24%), Positives = 68/151 (45%), Gaps = 1/151 (0%)
Frame = -3
Query: 72 NTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEF-VASGSQDTNIK 130
N + L +G Q+ + +WD+E + T +GHK ++ S+ P ASG++D +I
Sbjct: 1054 NDSQCLTASGDQT--VALWDVETTTKVTTFIGHKCSVRSVASCPSSPAQCASGARDGHIM 881
Query: 131 LWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTG 190
LWD R V + R H + + P + A + G M ++
Sbjct: 880 LWDSR----VNKKREHQPCSQVHQVCPQSGHQSKPAKHRRIHRAAGPKGVMDTQ-----Q 728
Query: 191 PVNVVEFHPNEYLLASGSSDRTIRFWDLEKF 221
V V + + +++SG++D ++ WD K+
Sbjct: 727 SVTCVLYQTDNLIISSGANDGCVKMWDTRKW 635
Score = 42.0 bits (97), Expect = 8e-04, Method: Compositional matrix adjust.
Identities = 59/268 (22%), Positives = 104/268 (38%), Gaps = 59/268 (22%)
Frame = -3
Query: 8 KTAWKLQEIVAHASNVSSLVLGKASGRLLATGGDDCRVNLWS--INKP---------NCI 56
+T K+ + H +V S+ +S A+G D + LW +NK + +
Sbjct: 997 ETTTKVTTFIGHKCSVRSVASCPSSPAQCASGARDGHIMLWDSRVNKKREHQPCSQVHQV 818
Query: 57 MSLTGHTS-PVESVRLN---------------------TPEELIVAGSQSGSIRVWD--- 91
+GH S P + R++ T +I +G+ G +++WD
Sbjct: 817 CPQSGHQSKPAKHRRIHRAAGPKGVMDTQQSVTCVLYQTDNLIISSGANDGCVKMWDTRK 638
Query: 92 ---------------LEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDI-- 134
+ +R L G I ++ P+ + D + + +
Sbjct: 637 WYTNTTTSLPVPVHTFDYPGHMRRLKG----IVTMCMDPWKSQLFVSYTDNKVYRYQLAG 470
Query: 135 -RRKGCVFRYRGHSQA---VRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEF-PGHT 189
R+ + Y GH VRC SPDGK+L S + +T +W++ F GHT
Sbjct: 469 QYREPQEYVYAGHRNDTFFVRCA-ISPDGKYLLSGSGRNTGVIWEVDKPNKRPLFLIGHT 293
Query: 190 GPVNVVEFHPNEYL-LASGSSDRTIRFW 216
V+ V++ + LA+ S DR++R W
Sbjct: 292 EDVSAVDWCSTDVCKLATVSDDRSLRIW 209
Score = 37.7 bits (86), Expect = 0.014, Method: Compositional matrix adjust.
Identities = 25/79 (31%), Positives = 36/79 (45%), Gaps = 1/79 (1%)
Frame = -3
Query: 140 VFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHP 199
V R+ H+ AV + + +A+ D TV LWD+ ++ F GH V V P
Sbjct: 1108 VHRWXAHNNAVFDYSWISNDSQCLTASGDQTVALWDVETTTKVTTFIGHKCSVRSVASCP 929
Query: 200 NE-YLLASGSSDRTIRFWD 217
+ ASG+ D I WD
Sbjct: 928 SSPAQCASGARDGHIMLWD 872
Score = 36.6 bits (83), Expect = 0.035, Method: Compositional matrix adjust.
Identities = 36/140 (25%), Positives = 55/140 (39%), Gaps = 2/140 (1%)
Frame = -3
Query: 38 TGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRL--NTPEELIVAGSQSGSIRVWDLEAA 95
T D V LW + + + GH V SV ++P + +G++ G I +WD
Sbjct: 1036 TASGDQTVALWDVETTTKVTTFIGHKCSVRSVASCPSSPAQC-ASGARDGHIMLWDSRVN 860
Query: 96 KILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRF 155
K + CS + SG Q K I R Q+V C+ +
Sbjct: 859 K------KREHQPCS---QVHQVCPQSGHQSKPAKHRRIHRAAGPKGVMDTQQSVTCVLY 707
Query: 156 SPDGKWLASAADDHTVKLWD 175
D ++S A+D VK+WD
Sbjct: 706 QTDNLIISSGANDGCVKMWD 647
>21921
Length = 1341
Score = 47.4 bits (111), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 22/61 (36%), Positives = 36/61 (59%)
Frame = -1
Query: 143 YRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEY 202
Y+GH+ VR + P G+WL S +DD T++ W++++G+ M G V V ++PN
Sbjct: 495 YKGHTGIVRSICPDPTGQWLVSGSDDGTIRFWEVSSGRCMKTL-QVGGCVTSVAWNPNPS 319
Query: 203 L 203
L
Sbjct: 318 L 316
Score = 40.4 bits (93), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 34/115 (29%), Positives = 56/115 (48%), Gaps = 2/115 (1%)
Frame = -1
Query: 185 FPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVLFNPD-G 243
+ GHTG V + P L SGS D TIRFW++ + + ++ G V SV +NP+
Sbjct: 495 YKGHTGIVRSICPDPTGQWLVSGSDDGTIRFWEVSSGRCMKTLQVG-GCVTSVAWNPNPS 319
Query: 244 CCLYSGCQDSLRVYGWEPERCFDVVLVNWGKVADLAICN-DQLIGVAFSQSNVSS 297
C+ + ++ V+L+N G L + N D+L+ + Q++ SS
Sbjct: 318 LCVVAATLNTT------------VLLINPGLGDKLVVSNTDKLLLASEDQASSSS 190
Score = 34.3 bits (77), Expect = 0.14, Method: Compositional matrix adjust.
Identities = 14/41 (34%), Positives = 26/41 (63%)
Frame = -1
Query: 61 GHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTL 101
GHT V S+ + + +V+GS G+IR W++ + + ++TL
Sbjct: 489 GHTGIVRSICPDPTGQWLVSGSDDGTIRFWEVSSGRCMKTL 367
Score = 31.6 bits (70), Expect = 0.92, Method: Compositional matrix adjust.
Identities = 16/67 (23%), Positives = 33/67 (49%)
Frame = -1
Query: 74 PEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWD 133
P++L+ + +R + A + + GH + S+ P G+++ SGS D I+ W+
Sbjct: 567 PQDLLPKLPKPKDLRPFPTTQALVYK---GHTGIVRSICPDPTGQWLVSGSDDGTIRFWE 397
Query: 134 IRRKGCV 140
+ C+
Sbjct: 396 VSSGRCM 376
>11915
Length = 737
Score = 47.4 bits (111), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 31/100 (31%), Positives = 51/100 (51%), Gaps = 5/100 (5%)
Frame = +1
Query: 72 NTPEELIVA-GSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEF-VASGSQDTNI 129
N L++A G SG I++W+ E K+L +M HKA + L F + S S D +
Sbjct: 430 NDSSTLVLATGHVSGRIKLWNCETGKLLIEMMDHKATVHDLHFAADNSLCLMSASHDGTV 609
Query: 130 KLWDIRRKGCVFRY---RGHSQAVRCLRFSPDGKWLASAA 166
KLW+ +G Y R +++ R+S D +++A+A
Sbjct: 610 KLWEFDDQGDCNMYLTLRTNAKHAFSCRWSHDRRYVATAG 729
Score = 35.8 bits (81), Expect = 0.061, Method: Compositional matrix adjust.
Identities = 16/50 (32%), Positives = 26/50 (52%), Gaps = 1/50 (2%)
Frame = +1
Query: 171 VKLWDLTAGKMMSEFPGHTGPVNVVEFHP-NEYLLASGSSDRTIRFWDLE 219
+KLW+ GK++ E H V+ + F N L S S D T++ W+ +
Sbjct: 478 IKLWNCETGKLLIEMMDHKATVHDLHFAADNSLCLMSASHDGTVKLWEFD 627
Score = 32.3 bits (72), Expect = 0.59, Method: Compositional matrix adjust.
Identities = 21/94 (22%), Positives = 43/94 (45%), Gaps = 1/94 (1%)
Frame = +1
Query: 1 MATPVVTKTAWKLQEIVAHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLT 60
++T K WK Q+ ++ S+LVL ATG R+ LW+ ++ +
Sbjct: 382 ISTNNCYKQRWKRQQ----QNDSSTLVL--------ATGHVSGRIKLWNCETGKLLIEMM 525
Query: 61 GHTSPVESVRLNTPEEL-IVAGSQSGSIRVWDLE 93
H + V + L +++ S G++++W+ +
Sbjct: 526 DHKATVHDLHFAADNSLCLMSASHDGTVKLWEFD 627
>19140
Length = 573
Score = 46.2 bits (108), Expect = 4e-05, Method: Compositional matrix adjust.
Identities = 34/120 (28%), Positives = 51/120 (42%), Gaps = 1/120 (0%)
Frame = -3
Query: 98 LRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSP 157
L L GH N+ +L + G SGS D I+LW + ++ CV +R H + V L+ +
Sbjct: 508 LMKLKGHTDNVKALVLNRDGTQCLSGSSDGTIRLWSLGQQRCVATFRVHDEGVWALQANE 329
Query: 158 DGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNE-YLLASGSSDRTIRFW 216
L S DH V D+ PV +E P + L ++D I+ W
Sbjct: 328 SFTTLYSGGRDHQVWATDIKNPDNRELICEEKAPVLKLELTPTDPPSLWVATTDSCIKNW 149
Score = 43.1 bits (100), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 23/80 (28%), Positives = 40/80 (50%)
Frame = -3
Query: 56 IMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHP 115
+M L GHT V+++ LN ++GS G+IR+W L + + T H + +L +
Sbjct: 508 LMKLKGHTDNVKALVLNRDGTQCLSGSSDGTIRLWSLGQQRCVATFRVHDEGVWALQANE 329
Query: 116 YGEFVASGSQDTNIKLWDIR 135
+ SG +D + DI+
Sbjct: 328 SFTTLYSGGRDHQVWATDIK 269
Score = 40.4 bits (93), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 25/102 (24%), Positives = 45/102 (44%)
Frame = -3
Query: 140 VFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHP 199
+ + +GH+ V+ L + DG S + D T++LW L + ++ F H V ++ +
Sbjct: 508 LMKLKGHTDNVKALVLNRDGTQCLSGSSDGTIRLWSLGQQRCVATFRVHDEGVWALQANE 329
Query: 200 NEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVLFNP 241
+ L SG D + D++ I E PV + P
Sbjct: 328 SFTTLYSGGRDHQVWATDIKNPDNRELICEEKAPVLKLELTP 203
Score = 36.2 bits (82), Expect = 0.046, Method: Compositional matrix adjust.
Identities = 25/76 (32%), Positives = 36/76 (47%)
Frame = -3
Query: 177 TAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRS 236
T K+M + GHT V + + + SGSSD TIR W L + + V+ V +
Sbjct: 520 TCHKLM-KLKGHTDNVKALVLNRDGTQCLSGSSDGTIRLWSLGQQRCVATFRVHDEGVWA 344
Query: 237 VLFNPDGCCLYSGCQD 252
+ N LYSG +D
Sbjct: 343 LQANESFTTLYSGGRD 296
>34005
Length = 456
Score = 46.2 bits (108), Expect = 4e-05, Method: Compositional matrix adjust.
Identities = 31/98 (31%), Positives = 49/98 (50%), Gaps = 6/98 (6%)
Frame = +1
Query: 148 QAVRCLRFSPDGKWLASAADDHTVKLWDLTAGK---MMSEFPGHTGPVNVVEFHPNEYLL 204
Q V L +SPD +LAS ++D++V +WD T G + H V V + P + +
Sbjct: 115 QEVCGLSWSPDATFLASGSNDNSVNIWDSTLGMDVPPLHTLTSHQAAVKAVAWCPWQTRM 294
Query: 205 ---ASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVLF 239
G++DR IRFW+ V ++ + V SVL+
Sbjct: 295 LATGGGTNDRHIRFWNTNTGACVKAVDTQS-QVCSVLW 405
Score = 33.5 bits (75), Expect = 0.29, Method: Compositional matrix adjust.
Identities = 21/78 (26%), Positives = 36/78 (46%), Gaps = 6/78 (7%)
Frame = +1
Query: 108 ICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCV---FRYRGHSQAVRCLRFSP-DGKWLA 163
+C L + P F+ASGS D ++ +WD V H AV+ + + P + LA
Sbjct: 121 VCGLSWSPDATFLASGSNDNSVNIWDSTLGMDVPPLHTLTSHQAAVKAVAWCPWQTRMLA 300
Query: 164 SAA--DDHTVKLWDLTAG 179
+ +D ++ W+ G
Sbjct: 301 TGGGTNDRHIRFWNTNTG 354
Score = 32.3 bits (72), Expect = 0.66, Method: Compositional matrix adjust.
Identities = 20/83 (24%), Positives = 34/83 (40%), Gaps = 6/83 (7%)
Frame = +1
Query: 77 LIVAGSQSGSIRVWDLEAAKI---LRTLMGHKANICSLDFHPYGE---FVASGSQDTNIK 130
+ +GS S+ +WD L TL H+A + ++ + P+ G+ D +I+
Sbjct: 154 FLASGSNDNSVNIWDSTLGMDVPPLHTLTSHQAAVKAVAWCPWQTRMLATGGGTNDRHIR 333
Query: 131 LWDIRRKGCVFRYRGHSQAVRCL 153
W+ CV SQ L
Sbjct: 334 FWNTNTGACVKAVDTQSQVCSVL 402
>01598
Length = 1545
Score = 45.8 bits (107), Expect = 5e-05, Method: Compositional matrix adjust.
Identities = 56/195 (28%), Positives = 80/195 (41%), Gaps = 30/195 (15%)
Frame = +1
Query: 77 LIVAGSQSGSIRVWDLEAAKIL--------RTLMGHKAN-------ICSLDFHPYGEFVA 121
LI GS+ +IRVW L K + R G + I L +P E +
Sbjct: 106 LIATGSKDRTIRVWTLSQGKQIFMKKLPNQRREAGDTGSRFKVWLAIHWLKSNP--EQLV 279
Query: 122 SGSQDTNIKLWDIR-RKGCVFR------YRGHSQAVRCLRFS-PDGKWLASAADDHTVKL 173
S S ++ LW +R KG ++ YR H + V + S PD K L + A D V L
Sbjct: 280 SSSSGGDLLLWSLRYTKGQAYQTFQTSDYRPHMRPVFNICASGPDSKTLCTFAQDRQVVL 459
Query: 174 WDL---TAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEK----FQVVSC 226
WDL A M+ GH V P +A G D IR W++ + V +
Sbjct: 460 WDLETMEAVASMATLGGHVYCVRTSPIDPGR--VAVGVGDSMIRTWNMSNKTNPYDVTTL 633
Query: 227 IEGEPGPVRSVLFNP 241
+G V +V ++P
Sbjct: 634 WQGIKSKVTAVAWHP 678
Score = 40.8 bits (94), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 28/101 (27%), Positives = 50/101 (49%), Gaps = 3/101 (2%)
Frame = +1
Query: 123 GSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSP--DGKWLASAADDHTVKLWDLTAGK 180
G ++T++ L +R GHSQ V + +SP D + L S D +WD+ G
Sbjct: 1246 GDKETSLILTSLRE------LSGHSQRVTDMSWSPHHDAR-LVSVGYDAEAFVWDVQKGT 1404
Query: 181 MMSEFPGHTGPVNVVEFHP-NEYLLASGSSDRTIRFWDLEK 220
+++F GH G + +F + L+ +G SD ++ W + +
Sbjct: 1405 ALAQFKGHMGRLLTCQFSGLDPDLVMTGGSDASVHVWRVSQ 1527
Score = 33.5 bits (75), Expect = 0.30, Method: Compositional matrix adjust.
Identities = 18/82 (21%), Positives = 40/82 (48%), Gaps = 2/82 (2%)
Frame = +1
Query: 98 LRTLMGHKANICSLDFHPYGEF-VASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFS 156
LR L GH + + + P+ + + S D +WD+++ + +++GH + +FS
Sbjct: 1279 LRELSGHSQRVTDMSWSPHHDARLVSVGYDAEAFVWDVQKGTALAQFKGHMGRLLTCQFS 1458
Query: 157 P-DGKWLASAADDHTVKLWDLT 177
D + + D +V +W ++
Sbjct: 1459 GLDPDLVMTGGSDASVHVWRVS 1524
Score = 32.0 bits (71), Expect = 0.86, Method: Compositional matrix adjust.
Identities = 16/79 (20%), Positives = 34/79 (43%), Gaps = 1/79 (1%)
Frame = +1
Query: 13 LQEIVAHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLN 72
L+E+ H+ V+ + L + G D +W + K + GH + + + +
Sbjct: 1279 LRELSGHSQRVTDMSWSPHHDARLVSVGYDAEAFVWDVQKGTALAQFKGHMGRLLTCQFS 1458
Query: 73 TPE-ELIVAGSQSGSIRVW 90
+ +L++ G S+ VW
Sbjct: 1459 GLDPDLVMTGGSDASVHVW 1515
Score = 28.9 bits (63), Expect = 7.6, Method: Compositional matrix adjust.
Identities = 16/84 (19%), Positives = 36/84 (42%), Gaps = 2/84 (2%)
Frame = +1
Query: 56 IMSLTGHTSPVESVRLNTPEEL-IVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFH 114
+ L+GH+ V + + + +V+ VWD++ L GH + + F
Sbjct: 1279 LRELSGHSQRVTDMSWSPHHDARLVSVGYDAEAFVWDVQKGTALAQFKGHMGRLLTCQFS 1458
Query: 115 PYG-EFVASGSQDTNIKLWDIRRK 137
+ V +G D ++ +W + ++
Sbjct: 1459 GLDPDLVMTGGSDASVHVWRVSQQ 1530
>30295
Length = 593
Score = 45.4 bits (106), Expect = 7e-05, Method: Compositional matrix adjust.
Identities = 33/123 (26%), Positives = 53/123 (43%), Gaps = 4/123 (3%)
Frame = +2
Query: 99 RTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPD 158
RTL H A I ++ + + S SQD + +WD V S V ++P
Sbjct: 227 RTLRXHLAKIYAMHWATDSRNLVSASQDGKLIVWDGYTTNKVHAIPLRSSWVMTCAYAPS 406
Query: 159 GKWLASAADDHTVKLWDLTAG----KMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIR 214
G ++A D+ ++ L ++ E PGHTG ++ F + ++ S S D T
Sbjct: 407 GGYVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFIDDNQIVTS-SGDMTCA 583
Query: 215 FWD 217
WD
Sbjct: 584 LWD 592
>21960
Length = 756
Score = 43.1 bits (100), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 27/75 (36%), Positives = 36/75 (48%), Gaps = 1/75 (1%)
Frame = +1
Query: 113 FHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQA-VRCLRFSPDGKWLASAADDHTV 171
F P+ E + SGS D NI WD + +G V CL P LA++ DH V
Sbjct: 388 FGPHSEHIISGSDDGNIFYWDKNTEAVTNFMKGDDAGVVNCLEQHPTMPVLATSGLDHNV 567
Query: 172 KLWDLTAGKMMSEFP 186
K+W +A K +E P
Sbjct: 568 KIWTPSA-KPETEVP 609
Score = 37.7 bits (86), Expect = 0.015, Method: Compositional matrix adjust.
Identities = 18/58 (31%), Positives = 30/58 (51%), Gaps = 1/58 (1%)
Frame = +1
Query: 76 ELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICS-LDFHPYGEFVASGSQDTNIKLW 132
E I++GS G+I WD + + G A + + L+ HP +A+ D N+K+W
Sbjct: 403 EHIISGSDDGNIFYWDKNTEAVTNFMKGDDAGVVNCLEQHPTMPVLATSGLDHNVKIW 576
Score = 35.0 bits (79), Expect = 0.10, Method: Compositional matrix adjust.
Identities = 19/67 (28%), Positives = 30/67 (44%), Gaps = 1/67 (1%)
Frame = +1
Query: 151 RCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGH-TGPVNVVEFHPNEYLLASGSS 209
R F P + + S +DD + WD + + G G VN +E HP +LA+
Sbjct: 376 RVNFFGPHSEHIISGSDDGNIFYWDKNTEAVTNFMKGDDAGVVNCLEQHPTMPVLATSGL 555
Query: 210 DRTIRFW 216
D ++ W
Sbjct: 556 DHNVKIW 576
Score = 28.5 bits (62), Expect = 8.8, Method: Compositional matrix adjust.
Identities = 38/172 (22%), Positives = 72/172 (41%), Gaps = 16/172 (9%)
Frame = +1
Query: 83 QSGSIRVWDLEA---AKILR--TLMGHKANICSLDFHPYG-EFVASGSQDTNIKLWDIRR 136
+ +++ +DL + +LR T + + S+ HP+ EF SGS D ++++D R+
Sbjct: 1 EDSTVKHFDLRSNCCTTMLRCYTKENRRVRLFSIAHHPFASEFCISGSDD-KLRVYDKRK 177
Query: 137 KGCVFRYRGHSQA----VRCLRFSPDGKWLASAADDHTVKLW--DLTAGKMMSEF--PGH 188
+ C ++ G + ++ D + L G+ +S H
Sbjct: 178 LDKTVHEMSPKDTKVSQITCAVYNHSGSEILASYSDAAIYLL*QPQLQGRRISALLRRPH 357
Query: 189 TGPVN--VVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVL 238
P + V F P+ + SGS D I +WD V + ++G+ V + L
Sbjct: 358 K*PYHQRVNFFGPHSEHIISGSDDGNIFYWDKNTEAVTNFMKGDDAGVVNCL 513
>04358
Length = 2430
Score = 42.0 bits (97), Expect = 7e-04, Method: Compositional matrix adjust.
Identities = 33/134 (24%), Positives = 59/134 (44%), Gaps = 11/134 (8%)
Frame = +1
Query: 119 FVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRF-SPDGKWLASAADDHTVKLWD-- 175
VA+ S + ++L+ R GH + +RF D + +A+ DHTV++WD
Sbjct: 1336 LVAAASSNFMVRLYSRCRLAQTNTLTGHDDVISSIRFLHTDPGLIMTASHDHTVRIWDPR 1515
Query: 176 LTAGKMMSEFPGHTG---PVNVVEFHPNEYLLASGSS----DRTIRFWDLEKFQVVSCIE 228
+ K + F G V + + ++ +L +G+ D + FWD K +++ C E
Sbjct: 1516 ASVSKEVQRFSGEQNTKCSVLSCDVNISDRVLCAGTEMSNDDAYLLFWDRRKDKLLGCYE 1695
Query: 229 -GEPGPVRSVLFNP 241
+ V F P
Sbjct: 1696 DSHHDDITQVHFGP 1737
Score = 38.5 bits (88), Expect = 0.008, Method: Compositional matrix adjust.
Identities = 41/189 (21%), Positives = 79/189 (41%), Gaps = 20/189 (10%)
Frame = +1
Query: 18 AHASNVSSLVLGKASGRLLATGGDDCRVNLWSI---NKPNCIMSLTGHTSPVESVRLNTP 74
+H +++ + G S + L TG D VN++ + + + +MS + VE P
Sbjct: 1699 SHHDDITQVHFGPTSEKTLLTGSTDGLVNVFDVMQTTEDDALMSTYNTEATVERAGWCGP 1878
Query: 75 E-ELIVAGSQSGSIRVWDLEAAKILRTLMGHKANI---CSLDFH----PYGEFVA----- 121
+ + + A + S VWD E + ++ L + + C D+ P + +
Sbjct: 1879 QSQQVYAITHMLSWHVWDTEKDEDVQQLTDLEQKLQGQCQADYLVDCIPANQSTSPPCLV 2058
Query: 122 SGSQDTNIKLWDIRRKGCVFRYR----GHSQAVRCLRFSPDGKWLASAADDHTVKLWDLT 177
+G+ ++ + D+ V R GH+ VRCL + + L + +D + LW
Sbjct: 2059 AGTHTGDLHVLDLSDLEEVKVVRSLSGGHTDTVRCLHWDKQTQTLVTGGEDSMLCLWSSD 2238
Query: 178 AGKMMSEFP 186
A + S P
Sbjct: 2239 ASGIQSPAP 2265
>21763
Length = 923
Score = 42.0 bits (97), Expect = 9e-04, Method: Compositional matrix adjust.
Identities = 39/157 (24%), Positives = 68/157 (43%), Gaps = 4/157 (2%)
Frame = +1
Query: 19 HASNVSSLVLGKASGRLLAT---GGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPE 75
H VS V A G AT GD V ++K + + ++ V+ +
Sbjct: 181 HPKEVSK-VTWHAKGDYFATVMPKGDKMSVLFHLLSKKHSQSPFSQSKGLIQCVKFHPLR 357
Query: 76 ELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIR 135
+ SQ +R+++L + ++ L + I S+D HP G+ V GS D +D+
Sbjct: 358 PIFFVASQR-FVRIYNLLTQQFVKKLQTNCKWISSMDVHPGGDNVIIGSYDCKSCWFDLD 534
Query: 136 RKGCVFR-YRGHSQAVRCLRFSPDGKWLASAADDHTV 171
++ R H +AVR + + ASA+DD ++
Sbjct: 535 LSTKPYKILRHHKRAVRHVSYHHRYPLFASASDDGSI 645
>16105
Length = 960
Score = 42.0 bits (97), Expect = 9e-04, Method: Compositional matrix adjust.
Identities = 33/122 (27%), Positives = 63/122 (51%), Gaps = 10/122 (8%)
Frame = -2
Query: 145 GHSQAVRCLRFSP-DGKWLASAADDHTVKLWDLTAGKMMS-------EFPGHTGPVNVVE 196
GH AV +++ P + +ASA+DD TVK+W + +++ + GH ++
Sbjct: 581 GHKGAVLDIQWCPHNDNVIASASDDCTVKVWQIPDSGLVTNLTDPVVDLVGHQKRCCLIV 402
Query: 197 FHPN-EYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVLFNPDGCCLYSGCQD-SL 254
+HP+ + +L S +D I FW++ + + ++ P + + FN +G L C+D L
Sbjct: 401 WHPSAQNVLVSAGADNKILFWNVGTGEPMLEVD-VPDMIYCMSFNFNGSRLVCTCKDKKL 225
Query: 255 RV 256
R+
Sbjct: 224 RI 219
Score = 40.0 bits (92), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 43/225 (19%), Positives = 85/225 (37%), Gaps = 13/225 (5%)
Frame = -2
Query: 6 VTKTAWKLQEIVAHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSP 65
+T+T+W+ + V+ + G L RV ++ P + GH
Sbjct: 728 ITRTSWESTYCAVNPKFVAVMTEAAGGGAFLVLPLS--RVGRVPVDNP----LVAGHKGA 567
Query: 66 VESVR-LNTPEELIVAGSQSGSIRVWDLEAAKILRTL-------MGHKANICSLDFHPYG 117
V ++ + +I + S +++VW + + ++ L +GH+ C + +HP
Sbjct: 566 VLDIQWCPHNDNVIASASDDCTVKVWQIPDSGLVTNLTDPVVDLVGHQKRCCLIVWHPSA 387
Query: 118 EFV-ASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDL 176
+ V S D I W++ + + C+ F+ +G L D +++ D
Sbjct: 386 QNVLVSAGADNKILFWNVGTGEPMLEVD-VPDMIYCMSFNFNGSRLVCTCKDKKLRIIDS 210
Query: 177 TAGKMMSEFPGHTG--PVNVVEFHPNEYLLASGS--SDRTIRFWD 217
+G ++ E H G P + S S+R WD
Sbjct: 209 HSGAVLKEGKCHDGAKPAQACYLKDGKVFTTGFSRMSERQYAIWD 75
>31384
Length = 474
Score = 40.8 bits (94), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 26/91 (28%), Positives = 45/91 (49%), Gaps = 5/91 (5%)
Frame = -1
Query: 107 NICSLDFHPYG---EFVASGSQDTNIKLWDIRRKGCVF--RYRGHSQAVRCLRFSPDGKW 161
++ L F P F+ SGS D + W++++ G + H+ V + +S DG
Sbjct: 270 SVSCLKFSPGALPSTFLISGSWDNKVSCWEVQQSGQTIPKAQQTHTGPVLDVDWSDDGTK 91
Query: 162 LASAADDHTVKLWDLTAGKMMSEFPGHTGPV 192
+ +A+ D T K+WDL + + M + H PV
Sbjct: 90 VFTASCDKTAKVWDLNSNQCM-QIAQHDAPV 1
Score = 38.9 bits (89), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 25/81 (30%), Positives = 44/81 (54%), Gaps = 5/81 (6%)
Frame = -1
Query: 149 AVRCLRFSPDG---KWLASAADDHTVKLWDLT-AGKMMSEFP-GHTGPVNVVEFHPNEYL 203
+V CL+FSP +L S + D+ V W++ +G+ + + HTGPV V++ +
Sbjct: 270 SVSCLKFSPGALPSTFLISGSWDNKVSCWEVQQSGQTIPKAQQTHTGPVLDVDWSDDGTK 91
Query: 204 LASGSSDRTIRFWDLEKFQVV 224
+ + S D+T + WDL Q +
Sbjct: 90 VFTASCDKTAKVWDLNSNQCM 28
>10162
Length = 1629
Score = 40.8 bits (94), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 37/171 (21%), Positives = 73/171 (42%), Gaps = 12/171 (7%)
Frame = +3
Query: 69 VRLNTPEELIVAGSQSGSIRVWDLEAAKILRTL--------MGHKANICSLDFHPYGEFV 120
V + LI++G + +V+++ + K+ ++ S+ F P +
Sbjct: 387 VDCSADNALIMSGCADATAKVFNVSSGKLXSAFNCAASQDSQDKDNSVESVAFCPVSPYA 566
Query: 121 ASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGK 180
A+ + ++++WD+ ++ H + V L++S L +A D +++WD +G
Sbjct: 567 ATATNSGSVQVWDLPTSVARHSFQ-HPEGVCKLQWSSSTALLYTACLDGVMRVWDARSGA 743
Query: 181 MMSEFPGHTGPVNVVEFH--PNEYLLASGSSDRTIRFW--DLEKFQVVSCI 227
+ GH +++F + L SGS D T R DL VS I
Sbjct: 744 SKAVLTGHARNSCILDFDVTRDGTCLVSGSEDGTARVLT*DLHSRNFVSVI 896
Score = 38.9 bits (89), Expect = 0.007, Method: Compositional matrix adjust.
Identities = 21/76 (27%), Positives = 36/76 (47%), Gaps = 2/76 (2%)
Frame = +3
Query: 106 ANICSLDFHPYGEFVASGSQDTNIKLWDI--RRKGCVFRYRGHSQAVRCLRFSPDGKWLA 163
++I L +H + +G+Q + LW + + + + H Q C + P+GK++
Sbjct: 30 SDITWLQWHGGAHVLLAGTQGGEVWLWQVPSQDYSKMKMLQSHGQPSLCGKILPNGKYVC 209
Query: 164 SAADDHTVKLWDLTAG 179
D VKLWDL G
Sbjct: 210 VGYSDGVVKLWDLKTG 257
Score = 35.8 bits (81), Expect = 0.058, Method: Compositional matrix adjust.
Identities = 21/72 (29%), Positives = 32/72 (44%), Gaps = 2/72 (2%)
Frame = +3
Query: 62 HTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPY--GEF 119
H V ++ ++ L+ G +RVWD + L GH N C LDF G
Sbjct: 639 HPEGVCKLQWSSSTALLYTACLDGVMRVWDARSGASKAVLTGHARNSCILDFDVTRDGTC 818
Query: 120 VASGSQDTNIKL 131
+ SGS+D ++
Sbjct: 819 LVSGSEDGTARV 854
>15745
Length = 1183
Score = 40.8 bits (94), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 22/54 (40%), Positives = 32/54 (59%), Gaps = 2/54 (3%)
Frame = +2
Query: 124 SQDTNIKLWDIRRKGCVFRYRG-HSQAVRCLRFSPDGKW-LASAADDHTVKLWD 175
+ + I+ WD+R K ++ G H Q VR L F+P+ ++ LAS DD VK WD
Sbjct: 638 ANEATIRGWDLRSKQQTYQMEGAHGQLVRDLDFNPNRQYYLASCGDDCRVKFWD 799
Score = 38.9 bits (89), Expect = 0.007, Method: Compositional matrix adjust.
Identities = 31/116 (26%), Positives = 56/116 (48%), Gaps = 11/116 (9%)
Frame = +2
Query: 113 FHPYGEF-VASGSQDTNIKLWDIR------RKGCVFRYRGHSQA-VRCLRFSPDGKWLAS 164
+HP G+ G + + +WD+ ++ + G Q + C R++P
Sbjct: 452 WHPTGDSQTVLGVCEDRVIMWDLNVASSSAQQTDMITLEGKGQPRLTCGRWNPHHNCAQI 631
Query: 165 A-ADDHTVKLWDLTAGKMMSEFPG-HTGPVNVVEFHPN-EYLLASGSSDRTIRFWD 217
A A++ T++ WDL + + + G H V ++F+PN +Y LAS D ++FWD
Sbjct: 632 ATANEATIRGWDLRSKQQTYQMEGAHGQLVRDLDFNPNRQYYLASCGDDCRVKFWD 799
Score = 38.1 bits (87), Expect = 0.011, Method: Compositional matrix adjust.
Identities = 22/64 (34%), Positives = 32/64 (50%), Gaps = 1/64 (1%)
Frame = +2
Query: 208 SSDRTIRFWDLEKFQVVSCIEGEPGP-VRSVLFNPDGCCLYSGCQDSLRVYGWEPERCFD 266
+++ TIR WDL Q +EG G VR + FNP+ + C D RV W+ C +
Sbjct: 638 ANEATIRGWDLRSKQQTYQMEGAHGQLVRDLDFNPNRQYYLASCGDDCRVKFWDTRNCSE 817
Query: 267 VVLV 270
+ V
Sbjct: 818 PLKV 829
>14500
Length = 1238
Score = 40.4 bits (93), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 22/45 (48%), Positives = 28/45 (62%)
Frame = +2
Query: 145 GHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHT 189
GHSQ V LR+SPDGK+LAS A+D+ + +W S P HT
Sbjct: 53 GHSQEVCGLRWSPDGKYLASGANDNLLCVWPAQVTGGNSTQPLHT 187
Score = 35.8 bits (81), Expect = 0.049, Method: Compositional matrix adjust.
Identities = 26/97 (26%), Positives = 45/97 (46%), Gaps = 2/97 (2%)
Frame = +3
Query: 80 AGSQSGSIRVWDLEAAKILRTLMGHKANICSLDF-HPYGEFVAS-GSQDTNIKLWDIRRK 137
G+ I W+ L ++ K+ +C+L + + E ++S G + +W
Sbjct: 261 GGTADRHIHFWNCNTGTNLSSV-DTKSQVCALLWSKEHRELISSHGFAQNQLIIWKYPAM 437
Query: 138 GCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLW 174
V GH+ V + SPDG+ + SAA D T++LW
Sbjct: 438 SRVAELTGHTARVLHMAMSPDGETVVSAAADETLRLW 548
Score = 30.8 bits (68), Expect(2) = 0.13, Method: Compositional matrix adjust.
Identities = 24/96 (25%), Positives = 43/96 (44%), Gaps = 2/96 (2%)
Frame = +3
Query: 123 GSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAAD--DHTVKLWDLTAGK 180
G+ D +I W+ + SQ V L +S + + L S+ + + +W A
Sbjct: 264 GTADRHIHFWNCNTGTNLSSVDTKSQ-VCALLWSKEHRELISSHGFAQNQLIIWKYPAMS 440
Query: 181 MMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFW 216
++E GHT V + P+ + S ++D T+R W
Sbjct: 441 RVAELTGHTARVLHMAMSPDGETVVSAAADETLRLW 548
Score = 22.3 bits (46), Expect(2) = 0.13, Method: Compositional matrix adjust.
Identities = 13/61 (21%), Positives = 30/61 (49%), Gaps = 5/61 (8%)
Frame = +2
Query: 56 IMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLE-----AAKILRTLMGHKANICS 110
+ +L+GH+ V +R + + + +G+ + VW + + + L T H+A + +
Sbjct: 38 VGTLSGHSQEVCGLRWSPDGKYLASGANDNLLCVWPAQVTGGNSTQPLHTFSQHQAAVKA 217
Query: 111 L 111
L
Sbjct: 218 L 220
Score = 34.3 bits (77), Expect = 0.16, Method: Compositional matrix adjust.
Identities = 18/59 (30%), Positives = 30/59 (50%), Gaps = 5/59 (8%)
Frame = +2
Query: 100 TLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGC-----VFRYRGHSQAVRCL 153
TL GH +C L + P G+++ASG+ D + +W + G + + H AV+ L
Sbjct: 44 TLSGHSQEVCGLRWSPDGKYLASGANDNLLCVWPAQVTGGNSTQPLHTFSQHQAAVKAL 220
>10264
Length = 416
Score = 40.4 bits (93), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 31/107 (28%), Positives = 52/107 (48%), Gaps = 6/107 (5%)
Frame = -1
Query: 116 YGEFVAS---GSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSP--DGKWLASAADDHT 170
+GE A+ G ++T + L +R GHSQ V + +SP D + L S D
Sbjct: 329 FGEMGATEREGDKETLLILTSLRE------LSGHSQRVTDMSWSPHHDAR-LVSVGYDAE 171
Query: 171 VKLWDLTAGKMMSEFPGHTGPVNVVEFHP-NEYLLASGSSDRTIRFW 216
+WD+ G +++F GH G + +F + L+ +G SD ++ W
Sbjct: 170 AFVWDVQKGTALAQFKGHMGRLLTCQFSGLDPDLVMTGGSDASVHVW 30
Score = 32.0 bits (71), Expect = 0.91, Method: Compositional matrix adjust.
Identities = 16/79 (20%), Positives = 34/79 (43%), Gaps = 1/79 (1%)
Frame = -1
Query: 13 LQEIVAHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLN 72
L+E+ H+ V+ + L + G D +W + K + GH + + + +
Sbjct: 266 LRELSGHSQRVTDMSWSPHHDARLVSVGYDAEAFVWDVQKGTALAQFKGHMGRLLTCQFS 87
Query: 73 TPE-ELIVAGSQSGSIRVW 90
+ +L++ G S+ VW
Sbjct: 86 GLDPDLVMTGGSDASVHVW 30
>31474
Length = 403
Score = 40.0 bits (92), Expect = 0.003, Method: Composition-based stats.
Identities = 25/98 (25%), Positives = 44/98 (44%), Gaps = 5/98 (5%)
Frame = -3
Query: 145 GHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFP---GHTGPVNVVEFHPNE 201
H + C+ ++P G LAS D +K+W + + HT V + + P
Sbjct: 311 AHDEHAWCVAWNPTGTLLASCGSDKIIKIWGKEGDNWVCKSTLTDAHTRTVRSLGWSPCG 132
Query: 202 YLLASGSSDRTIRFWDLE--KFQVVSCIEGEPGPVRSV 237
L+S S D T W + +F+ ++ +EG V++V
Sbjct: 131 NYLSSASFDATTAVWSRKGGEFECIATLEGHENEVKAV 18
>17298
Length = 476
Score = 40.0 bits (92), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 15/43 (34%), Positives = 27/43 (62%)
Frame = -1
Query: 175 DLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWD 217
++ +G+ + ++ H G VN V+F+ ++ SGS D T+R WD
Sbjct: 254 NVASGQALRKYRDHAGTVNCVKFNEESTVILSGSLDNTVRAWD 126
Score = 35.8 bits (81), Expect = 0.060, Method: Compositional matrix adjust.
Identities = 18/75 (24%), Positives = 37/75 (49%)
Frame = -1
Query: 142 RYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNE 201
+YR H+ V C++F+ + + S + D+TV+ WD + +V ++
Sbjct: 227 KYRDHAGTVNCVKFNEESTVILSGSLDNTVRAWDTRSRSHTPIQVLDEATDSVTSIQVSD 48
Query: 202 YLLASGSSDRTIRFW 216
Y + +GS+D +R +
Sbjct: 47 YEILTGSADGRVRRY 3
>15972
Length = 1069
Score = 40.0 bits (92), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 21/71 (29%), Positives = 33/71 (46%)
Frame = +3
Query: 99 RTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPD 158
RT GHK + L HP G+ + SQD ++LW+ G + +A +R++P
Sbjct: 219 RTFSGHKGPVRHLAVHPSGKLTLTVSQDRTLRLWN-NMNGRIAFISNMKEAAESVRWAPG 395
Query: 159 GKWLASAADDH 169
G + A H
Sbjct: 396 GLYYVVAFRSH 428
Score = 39.7 bits (91), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 24/78 (30%), Positives = 35/78 (44%)
Frame = +3
Query: 185 FPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVLFNPDGC 244
F GH GPV + HP+ L + S DRT+R W+ + ++ I SV + P G
Sbjct: 225 FSGHKGPVRHLAVHPSGKLTLTVSQDRTLRLWNNMNGR-IAFISNMKEAAESVRWAPGGL 401
Query: 245 CLYSGCQDSLRVYGWEPE 262
+ L VY E +
Sbjct: 402 YYVVAFRSHLDVYSVESK 455
Score = 32.0 bits (71), Expect = 0.77, Method: Compositional matrix adjust.
Identities = 13/39 (33%), Positives = 21/39 (53%)
Frame = +3
Query: 143 YRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKM 181
+ GH VR L P GK + + D T++LW+ G++
Sbjct: 225 FSGHKGPVRHLAVHPSGKLTLTVSQDRTLRLWNNMNGRI 341
>31118
Length = 390
Score = 39.7 bits (91), Expect = 0.004, Method: Composition-based stats.
Identities = 20/64 (31%), Positives = 33/64 (51%), Gaps = 5/64 (7%)
Frame = -2
Query: 146 HSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPG-----HTGPVNVVEFHPN 200
HS +RC+RFSP ++ + + D T+KL DL G + ++ H + +HP
Sbjct: 383 HSAEIRCIRFSPSAYYMLTCSYDSTIKLTDLQ-GDLANDIASVVVAKHKDKAITIRWHPT 207
Query: 201 EYLL 204
E+ L
Sbjct: 206 EFPL 195
>25400
Length = 462
Score = 39.7 bits (91), Expect = 0.004, Method: Composition-based stats.
Identities = 17/57 (29%), Positives = 33/57 (57%), Gaps = 1/57 (1%)
Frame = +3
Query: 78 IVAGSQSGSIRVWDLEAAKILRTL-MGHKANICSLDFHPYGEFVASGSQDTNIKLWD 133
+ +G +G+I ++DL +++R L GH++ + + +HPY + S S D + WD
Sbjct: 6 VYSGCATGTILIYDLLTGRVVRKLDGGHRSCVRDVSWHPYTNTLISSSWDGTVGKWD 176
Score = 33.1 bits (74), Expect = 0.36, Method: Composition-based stats.
Identities = 22/70 (31%), Positives = 35/70 (50%), Gaps = 1/70 (1%)
Frame = +3
Query: 170 TVKLWDLTAGKMMSEFPG-HTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIE 228
T+ ++DL G+++ + G H V V +HP L S S D T+ WD + +
Sbjct: 30 TILIYDLLTGRVVRKLDGGHRSCVRDVSWHPYTNTLISSSWDGTVGKWDYFDYWAH---D 200
Query: 229 GEPGPVRSVL 238
GE G V+ V+
Sbjct: 201 GEEGEVKMVV 230
>16436
Length = 1316
Score = 39.3 bits (90), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 27/102 (26%), Positives = 50/102 (49%), Gaps = 4/102 (3%)
Frame = +3
Query: 77 LIVAGSQSGSIRVWDL-EAAKILRTLMGHKANICSLDFHPYGEFVASGSQD-TNIKLWDI 134
L G + G +++ DL + K + H+AN+C + + G +A+ S+ T I+++D
Sbjct: 138 LAFPGRKLGHVQIVDLADTEKAAMDIAAHEANLCCMAMNMGGSRLATASEKGTLIRVFDA 317
Query: 135 RRKGCVFRYR--GHSQAVRCLRFSPDGKWLASAADDHTVKLW 174
+ R +S + C+ FS D L A+D TV ++
Sbjct: 318 VSGAQLHELRRGANSANIYCINFSADSTLLCVASDHGTVHIF 443
>02948
Length = 1207
Score = 38.5 bits (88), Expect = 0.010, Method: Compositional matrix adjust.
Identities = 28/118 (23%), Positives = 48/118 (40%), Gaps = 2/118 (1%)
Frame = -2
Query: 114 HPYGEFVASGSQDTNIKLW-DIRRKGCVFRY-RGHSQAVRCLRFSPDGKWLASAADDHTV 171
HP +A+G I W + + V HS V CL F+P+G L S + T+
Sbjct: 729 HPTDVCIATGHASGKITFWWNFDQDKTVLSVSHWHSLPVTCLAFTPEGSCLLSGGHECTL 550
Query: 172 KLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEG 229
W + + + P P++ + P+ +G SD ++ F ++ I G
Sbjct: 549 VRWQMNS-EHKEFLPRLGAPLHNIVVSPDGVFFVTGHSDNVLQVIT-SSFSIMXAIRG 382
Score = 35.4 bits (80), Expect = 0.072, Method: Compositional matrix adjust.
Identities = 21/58 (36%), Positives = 29/58 (50%), Gaps = 3/58 (5%)
Frame = -2
Query: 195 VEFHPNEYLLASGSSDRTIRFW---DLEKFQVVSCIEGEPGPVRSVLFNPDGCCLYSG 249
V HP + +A+G + I FW D +K V+S PV + F P+G CL SG
Sbjct: 738 VSCHPTDVCIATGHASGKITFWWNFDQDK-TVLSVSHWHSLPVTCLAFTPEGSCLLSG 568
>06799
Length = 616
Score = 37.4 bits (85), Expect = 0.019, Method: Compositional matrix adjust.
Identities = 38/161 (23%), Positives = 69/161 (42%), Gaps = 15/161 (9%)
Frame = +3
Query: 33 GRLLATGGDDCRVNLWSI--NKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVW 90
G L+ DD ++LW+ KP + SL + L + + G++ G++ +
Sbjct: 21 GALVTVCADDT-LHLWNYRQKKPEIVHSLKFQRERITYCHLPFQSKWLYIGTERGNVHIV 197
Query: 91 DLEAAKILRTLMG-HKANICSLDFHPYGEFVA------------SGSQDTNIKLWDIRRK 137
++E+ + ++ +KA S HP G V G + I LWD+R K
Sbjct: 198 NIESFILSGYIINWNKAIELSRKTHP-GPVVHLSDNPVDSNKLLIGFESGAIVLWDLRSK 374
Query: 138 GCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTA 178
RY +A+R + + +GK + D ++ W+L A
Sbjct: 375 AAECRYNS-PEALRSIAWHFEGKQFMCSHSDGSLTTWNLKA 494
>37142
Length = 327
Score = 37.4 bits (85), Expect = 0.020, Method: Compositional matrix adjust.
Identities = 20/67 (29%), Positives = 38/67 (56%), Gaps = 7/67 (10%)
Frame = +2
Query: 77 LIVAGSQSGSIRVW------DLEAAKILRTLMGHKANICSLDFHPY-GEFVASGSQDTNI 129
+IV G+ +GS+ V+ D +A + L H + +LDF+P+ +ASG+ ++ I
Sbjct: 2 VIVGGADNGSVLVYSAQKMIDGDADCSVLQLTKHTGAVKALDFNPFQTNLLASGASESEI 181
Query: 130 KLWDIRR 136
+WD+ +
Sbjct: 182 YIWDLNK 202
Score = 36.6 bits (83), Expect = 0.035, Method: Compositional matrix adjust.
Identities = 20/50 (40%), Positives = 29/50 (58%), Gaps = 1/50 (2%)
Frame = +2
Query: 172 KLWDLTAGKMMSEFPGHTGPVNVVEFHPNEY-LLASGSSDRTIRFWDLEK 220
K+ D A + + HTG V ++F+P + LLASG+S+ I WDL K
Sbjct: 53 KMIDGDADCSVLQLTKHTGAVKALDFNPFQTNLLASGASESEIYIWDLNK 202
Score = 32.0 bits (71), Expect = 0.72, Method: Compositional matrix adjust.
Identities = 20/79 (25%), Positives = 35/79 (44%), Gaps = 3/79 (3%)
Frame = +2
Query: 15 EIVAHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRL--- 71
++ H V +L LLA+G + + +W +NKP+ M+ + P E V
Sbjct: 89 QLTKHTGAVKALDFNPFQTNLLASGASESEIYIWDLNKPDNPMTPGQKSQPPEEVSCVAW 268
Query: 72 NTPEELIVAGSQSGSIRVW 90
N + I+A + + VW
Sbjct: 269 NRQVQHILASNFAARCVVW 325
>05642
Length = 445
Score = 37.0 bits (84), Expect = 0.022, Method: Composition-based stats.
Identities = 20/58 (34%), Positives = 33/58 (56%), Gaps = 1/58 (1%)
Frame = -1
Query: 203 LLASGSSDRTIRFWDLEKFQVVSCIEGEPG-PVRSVLFNPDGCCLYSGCQDSLRVYGW 259
L+ SGS D + FWDL + ++V ++ + PV S+ F+ CL + C D +V+ W
Sbjct: 367 LVVSGSEDGKVYFWDLVEAKLVDTLDHKTTRPVHSLSFHHAELCLMTACAD--KVFLW 200
>20662
Length = 1220
Score = 37.0 bits (84), Expect = 0.023, Method: Compositional matrix adjust.
Identities = 34/140 (24%), Positives = 57/140 (40%), Gaps = 7/140 (5%)
Frame = +2
Query: 36 LATGGDDCRVNLWSINKPNCIMSLTG----HTSPVESVRLNTPEELIVAGSQSGSIRVWD 91
L TGG V LW + + + S+ H SV +N+ ++ S I+VW+
Sbjct: 305 LDTGG----VALWELQDEDKMFSMLSSACEHDDMTASVSINSDXSHYLSASYDHGIKVWN 472
Query: 92 LEAAKILRTLMGHKANICSLDFHPYG-EFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAV 150
+ L T H + + HP S SQD I LWD+R S
Sbjct: 473 TDLTS-LYTYRAHSDIVWDVQCHPTEPALFLSCSQDGKIVLWDVRESKPATCLPKCSSGF 649
Query: 151 R--CLRFSPDGKWLASAADD 168
+ C+++ P+ + + + D+
Sbjct: 650 KPTCVQWQPNARNMYAVGDE 709
>38177
Length = 430
Score = 36.6 bits (83), Expect = 0.029, Method: Compositional matrix adjust.
Identities = 25/95 (26%), Positives = 42/95 (44%), Gaps = 6/95 (6%)
Frame = +3
Query: 111 LDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRY----RGHSQAVRCLRFSPDGKWLASAA 166
L + P G + +G+ LW+ G F + + H +VR +R+S +W+ +A
Sbjct: 6 LAWTPEGRRLVTGASSGEFTLWN----GLTFNFETILQAHDVSVRAMRWSNHDQWMVTAD 173
Query: 167 DDHTVKLW--DLTAGKMMSEFPGHTGPVNVVEFHP 199
+K W ++ KM F GH P+ V P
Sbjct: 174 HSGYIKYWQSNMNNVKM---FQGHKEPIRGVRLAP 269
Score = 35.0 bits (79), Expect = 0.099, Method: Compositional matrix adjust.
Identities = 19/92 (20%), Positives = 36/92 (39%)
Frame = +3
Query: 152 CLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDR 211
CL ++P+G+ L + A LW+ + H V + + ++ + +
Sbjct: 3 CLAWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDVSVRAMRWSNHDQWMVTADHSG 182
Query: 212 TIRFWDLEKFQVVSCIEGEPGPVRSVLFNPDG 243
I++W V +G P+R V P G
Sbjct: 183 YIKYWQ-SNMNNVKMFQGHKEPIRGVRLAPPG 275
>04395
Length = 1145
Score = 36.6 bits (83), Expect = 0.037, Method: Compositional matrix adjust.
Identities = 34/126 (26%), Positives = 58/126 (46%), Gaps = 16/126 (12%)
Frame = +3
Query: 28 LGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPV------ESVRLNT----PEEL 77
L S +L +GG+D R+ L S GH +PV +S +N +
Sbjct: 231 LASYSXDVLMSGGEDGRLALLS----------PGHATPVRLMEKADSCTINALTFLKQSQ 380
Query: 78 IVAGSQSGSIRVWDL-----EAAKILRTLMGHKANICSLDFHPYG-EFVASGSQDTNIKL 131
++ + G ++++D+ E A+I H + +C +D HP VA+GSQD + +
Sbjct: 381 VLTVNSFGQLKLFDVRQNSDEPAQIFSATDDHWSLLC-VDKHPGQLHIVATGSQDGTLTV 557
Query: 132 WDIRRK 137
WD+R
Sbjct: 558 WDLRHH 575
>39204
Length = 1684
Score = 35.8 bits (81), Expect = 0.049, Method: Compositional matrix adjust.
Identities = 19/38 (50%), Positives = 20/38 (52%), Gaps = 6/38 (15%)
Frame = -2
Query: 146 HSQAVRCLRFSP------DGKWLASAADDHTVKLWDLT 177
H +AVRCLRF P L SA DD KLW LT
Sbjct: 1272 HYKAVRCLRFKPVTDSESPAPMLVSAGDDGMFKLWTLT 1159
>07665
Length = 435
Score = 35.0 bits (79), Expect = 0.099, Method: Compositional matrix adjust.
Identities = 32/99 (32%), Positives = 48/99 (48%), Gaps = 11/99 (11%)
Frame = -2
Query: 90 WDLEAAKILRTLMGHKANICSLDFHP--YGEFVASGSQDTNIKLWDIRRKGCVFRYR--- 144
WDL K L TL H I +L F P Y VA G +IK+WD+ K V R
Sbjct: 392 WDLNDGKNLYTLE-HNDIINALCFSPNRYWLCVAYGP---SIKIWDLACKKTVEELRPEV 225
Query: 145 ----GHSQAVRCLR--FSPDGKWLASAADDHTVKLWDLT 177
++ +CL +S DG+ L + D+T+++W ++
Sbjct: 224 VSPTSKAEQPQCLSLAWSTDGQTLFAGYSDNTIRVWQVS 108
>13890
Length = 630
Score = 34.7 bits (78), Expect = 0.13, Method: Compositional matrix adjust.
Identities = 25/82 (30%), Positives = 39/82 (47%), Gaps = 11/82 (13%)
Frame = +1
Query: 113 FHPYG-EFVASGSQDTNIKLWDIRRKGCVFRYRGHSQ---AVRCLRFSPDGKWLASAAD- 167
FHP VA+G+ D I++WD+R R H + V+ + FS DG+ + S D
Sbjct: 4 FHPVTPHLVATGTTDC-IQVWDVRHPEVPVRVLTHKEQLGQVQDVMFSHDGQEVFSCGDV 180
Query: 168 ------DHTVKLWDLTAGKMMS 183
D ++ WD G ++S
Sbjct: 181 VSRESSDRSIMAWDFRTGVILS 246
>05303
Length = 782
Score = 34.3 bits (77), Expect = 0.15, Method: Compositional matrix adjust.
Identities = 29/115 (25%), Positives = 48/115 (41%), Gaps = 16/115 (13%)
Frame = -3
Query: 39 GGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPE------------ELIVAGSQSGS 86
GG D V+LW++NK ++ +T S + + E +L+ GS+ G
Sbjct: 648 GGQDNSVSLWNVNKKKALVCVTSAHSGCSQIEGSKGENWITAVASLQFTDLVATGSKDGC 469
Query: 87 IRVWDLEAAKILRTLMGH---KANICSLDFHPYGEFVASG-SQDTNIKLWDIRRK 137
IR+W A + + SL F G+F+ +G Q+ + W RK
Sbjct: 468 IRLWQCSANFHHLVPLXSVPVPGFVNSLKFSSKGDFLLAGVGQEHRLGRWWSLRK 304
>35695
Length = 1651
Score = 34.3 bits (77), Expect = 0.15, Method: Compositional matrix adjust.
Identities = 24/98 (24%), Positives = 48/98 (48%), Gaps = 2/98 (2%)
Frame = -1
Query: 18 AHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKP-NCIMSLTGHTSPVESVRLNTPEE 76
AH + +L ++ + D +N+W+ +K + L P+E+V +
Sbjct: 1591 AHFGRIIALTSVTVGCNMVISSSIDKTINVWNFDKILEEVHPLDRMERPIETVHMAASSS 1412
Query: 77 LIVAGSQSGSIRVWDLEAAKILRTLMG-HKANICSLDF 113
L VA +++ + VWDLE ++++ L+G ++N S F
Sbjct: 1411 LCVATTRNQT-SVWDLETGRLVKVLVGSSRSNXVSQAF 1301
>04524
Length = 1340
Score = 33.9 bits (76), Expect = 0.21, Method: Compositional matrix adjust.
Identities = 32/165 (19%), Positives = 70/165 (42%), Gaps = 16/165 (9%)
Frame = -1
Query: 33 GRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPV-----ESVRLNTPEELIVAGSQSGSI 87
GR LA D ++++++ + P+ S +S + SV + E ++ ++G +
Sbjct: 1289 GRYLAVCDDXKKLHVFTRDAPHTPQSWALISSRLLARRATSVTFTSDEGQVIVADKTGDV 1110
Query: 88 RVW----------DLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRK 137
+ + E + L+GH + + + V + +D I++
Sbjct: 1109 YTFPTTTQVEVKDEGEVKTHGQLLLGHLSMVLDVCLTGREGHVVTCDRDEKIRVSQFPNA 930
Query: 138 GCVFRY-RGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKM 181
+ Y GH+Q V CL + + + L S + D TV+ W++ ++
Sbjct: 929 YNIHTYCLGHTQFVNCLVYVEEFRVLISGSGDCTVRAWNMEGKQL 795
Score = 31.2 bits (69), Expect = 1.5, Method: Compositional matrix adjust.
Identities = 18/52 (34%), Positives = 27/52 (51%), Gaps = 10/52 (19%)
Frame = -1
Query: 182 MSEFP----------GHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQV 223
+S+FP GHT VN + + +L SGS D T+R W++E Q+
Sbjct: 950 VSQFPNAYNIHTYCLGHTQFVNCLVYVEEFRVLISGSGDCTVRAWNMEGKQL 795
>36111
Length = 687
Score = 33.5 bits (75), Expect = 0.25, Method: Compositional matrix adjust.
Identities = 18/56 (32%), Positives = 25/56 (44%)
Frame = +2
Query: 191 PVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVLFNPDGCCL 246
PVN V FH A+G SD + WD + + P + S+ F+ DG L
Sbjct: 236 PVNAVAFHNVYNTFATGGSDGYVNIWDGFHKKRLCXFHRYPTSIASLAFSHDGNVL 403
>25880
Length = 423
Score = 33.5 bits (75), Expect = 0.27, Method: Composition-based stats.
Identities = 22/71 (30%), Positives = 31/71 (43%)
Frame = +2
Query: 62 HTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVA 121
H V+SV + E IV GS +RV++LE L G + A
Sbjct: 53 HKHIVKSVAFDNSSENIVTGSNEKLVRVFNLEQPDAEPELYGGHTGAIKRALY------A 214
Query: 122 SGSQDTNIKLW 132
SGS+D ++LW
Sbjct: 215 SGSEDGTLRLW 247
Score = 33.5 bits (75), Expect = 0.31, Method: Composition-based stats.
Identities = 21/88 (23%), Positives = 41/88 (46%), Gaps = 1/88 (1%)
Frame = +2
Query: 130 KLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSE-FPGH 188
K+W+ + ++ H V+ + F + + + +++ V++++L E + GH
Sbjct: 8 KVWNAVSGAEIHSFQ-HKHIVKSVAFDNSSENIVTGSNEKLVRVFNLEQPDAEPELYGGH 184
Query: 189 TGPVNVVEFHPNEYLLASGSSDRTIRFW 216
TG + L ASGS D T+R W
Sbjct: 185 TGAIK-------RALYASGSEDGTLRLW 247
>30108
Length = 1032
Score = 33.1 bits (74), Expect = 0.40, Method: Compositional matrix adjust.
Identities = 31/110 (28%), Positives = 43/110 (39%), Gaps = 12/110 (10%)
Frame = +1
Query: 108 ICSLDFHPYGEFVASGSQ-DTNIKLWDIRRKGC-VFRYRGHSQAVRCLRFSPDGKWLASA 165
I L + P + S S DT + W + + C RY G V L SPDG + +A
Sbjct: 388 ITHLAWLPSANILLSASPVDTAVMAWSVGGEACTALRYLG-GGGVSLLACSPDGSKVMAA 564
Query: 166 ADDHTVKLWDLT----------AGKMMSEFPGHTGPVNVVEFHPNEYLLA 205
++WD T +G+ S H G V V +E L A
Sbjct: 565 TPATLFRVWDTTSWHCEVWSQLSGRCTSACWSHDGQVXVFSMEGDEALHA 714
>27681
Length = 465
Score = 32.7 bits (73), Expect = 0.44, Method: Compositional matrix adjust.
Identities = 25/98 (25%), Positives = 49/98 (50%), Gaps = 14/98 (14%)
Frame = +2
Query: 108 ICSLDFHPYGEFVASGSQDTNIKLWDIRRKG------CVFRY---RGHSQA-----VRCL 153
IC+ ++P + +ASGS D+ ++W++ + V R+ +G ++ V L
Sbjct: 8 ICA--WNPTNDLLASGSGDSTARIWNMTSETPNNANQLVLRHCIQKGGTEVPSNKDVTSL 181
Query: 154 RFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGP 191
++ +G LA+ + D +LW T G +++ H GP
Sbjct: 182 DWNSEGTLLATGSYDGYARLW-RTDGHLVNTLGQHKGP 292
Score = 31.6 bits (70), Expect = 1.0, Method: Compositional matrix adjust.
Identities = 19/75 (25%), Positives = 36/75 (48%), Gaps = 14/75 (18%)
Frame = +2
Query: 72 NTPEELIVAGSQSGSIRVWDLEAAK-------ILR-------TLMGHKANICSLDFHPYG 117
N +L+ +GS + R+W++ + +LR T + ++ SLD++ G
Sbjct: 20 NPTNDLLASGSGDSTARIWNMTSETPNNANQLVLRHCIQKGGTEVPSNKDVTSLDWNSEG 199
Query: 118 EFVASGSQDTNIKLW 132
+A+GS D +LW
Sbjct: 200 TLLATGSYDGYARLW 244
Score = 30.4 bits (67), Expect = 2.1, Method: Compositional matrix adjust.
Identities = 23/75 (30%), Positives = 35/75 (46%), Gaps = 14/75 (18%)
Frame = +2
Query: 192 VNVVEFHPNEYLLASGSSDRTIRFWDL--------EKFQVVSCIE--GEPGP----VRSV 237
V + ++P LLASGS D T R W++ + + CI+ G P V S+
Sbjct: 2 VFICAWNPTNDLLASGSGDSTARIWNMTSETPNNANQLVLRHCIQKGGTEVPSNKDVTSL 181
Query: 238 LFNPDGCCLYSGCQD 252
+N +G L +G D
Sbjct: 182 DWNSEGTLLATGSYD 226
>13486
Length = 1509
Score = 32.7 bits (73), Expect = 0.52, Method: Compositional matrix adjust.
Identities = 13/43 (30%), Positives = 22/43 (51%)
Frame = -1
Query: 54 NCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAK 96
+C+ L GH++PV V N E L+ + G + +W E +
Sbjct: 927 SCVNKLLGHSAPVLDVCFNCDESLLASCDAQGMVIIWKREGKQ 799
>30297
Length = 822
Score = 32.3 bits (72), Expect = 0.54, Method: Compositional matrix adjust.
Identities = 20/67 (29%), Positives = 31/67 (46%), Gaps = 10/67 (14%)
Frame = -1
Query: 129 IKLWDIRRK----------GCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTA 178
I +WDI + + +RGH ++V CL K L ++A D TV++W T
Sbjct: 312 IYVWDISQYCLETPETDSPDVIQSWRGHVESVSCLDLVEQNKVLLTSAADCTVRMW-TTD 136
Query: 179 GKMMSEF 185
G + F
Sbjct: 135 GHYIGTF 115
>27475
Length = 369
Score = 32.3 bits (72), Expect = 0.65, Method: Compositional matrix adjust.
Identities = 15/34 (44%), Positives = 20/34 (58%), Gaps = 1/34 (2%)
Frame = +2
Query: 185 FPGHTGPVNVVEFHPN-EYLLASGSSDRTIRFWD 217
F HTG V V++ P E+L SGS D ++ WD
Sbjct: 56 FTSHTGWVTGVDWSPTREHLFLSGSYDNVLKLWD 157
Score = 29.6 bits (65), Expect = 4.2, Method: Compositional matrix adjust.
Identities = 18/68 (26%), Positives = 28/68 (41%), Gaps = 2/68 (2%)
Frame = +2
Query: 91 DLEAAKILRTLMGHKANICSLDFHPYGE-FVASGSQDTNIKLWDIRR-KGCVFRYRGHSQ 148
D E + H + +D+ P E SGS D +KLWD R K ++ H
Sbjct: 26 DTEGETVKCAFTSHTGWVTGVDWSPTREHLFLSGSYDNVLKLWDTRSPKATLYDMNWHED 205
Query: 149 AVRCLRFS 156
+ + +S
Sbjct: 206 RILAVDWS 229
>07781
Length = 1269
Score = 32.0 bits (71), Expect = 0.83, Method: Compositional matrix adjust.
Identities = 17/62 (27%), Positives = 33/62 (53%), Gaps = 4/62 (6%)
Frame = -2
Query: 78 IVAGSQSGSIRVWDLEAAKILRT----LMGHKANICSLDFHPYGEFVASGSQDTNIKLWD 133
++ +G++ V+++E+ + T +A IC+ D E + SGS D +K+WD
Sbjct: 881 VITSDSAGNLTVFEVESTTVRETSQWRAHDFEAWICAFD-QWNTELIYSGSDDCKLKVWD 705
Query: 134 IR 135
+R
Sbjct: 704 LR 699
Score = 32.0 bits (71), Expect = 0.83, Method: Compositional matrix adjust.
Identities = 26/103 (25%), Positives = 46/103 (44%), Gaps = 3/103 (2%)
Frame = -2
Query: 142 RYRGHS-QAVRCLRFSPDGKWLASAADDHTVKLWDLTAGK--MMSEFPGHTGPVNVVEFH 198
++R H +A C + + + S +DD +K+WDL G +++ G ++
Sbjct: 809 QWRAHDFEAWICAFDQWNTELIYSGSDDCKLKVWDLRVGTTPVLTNSRFTMGVTSIQSCP 630
Query: 199 PNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVLFNP 241
E+LLA GS D +R +D + G V V ++P
Sbjct: 629 QREHLLAVGSYDENLRLFDTRHMRQPLSTTALEGGVWRVKWDP 501
Score = 31.6 bits (70), Expect = 1.1, Method: Compositional matrix adjust.
Identities = 23/67 (34%), Positives = 32/67 (47%), Gaps = 6/67 (8%)
Frame = -2
Query: 76 ELIVAGSQSGSIRVWDLEAAKI-----LRTLMGHKANICSLDFHPYGE-FVASGSQDTNI 129
ELI +GS ++VWDL R MG + S+ P E +A GS D N+
Sbjct: 752 ELIYSGSDDCKLKVWDLRVGTTPVLTNSRFTMG----VTSIQSCPQREHLLAVGSYDENL 585
Query: 130 KLWDIRR 136
+L+D R
Sbjct: 584 RLFDTRH 564
>22113
Length = 614
Score = 30.8 bits (68), Expect = 1.6, Method: Compositional matrix adjust.
Identities = 17/78 (21%), Positives = 33/78 (42%)
Frame = +3
Query: 141 FRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPN 200
++ H V LRF+ GKW S D+ + W G + + T V + +
Sbjct: 84 YQLHLHESCVLSLRFATCGKWFVSTGKDNLLNAWRTPYGASIFQ-SKETSSVLSCDISTD 260
Query: 201 EYLLASGSSDRTIRFWDL 218
+ + +GS D+ +++
Sbjct: 261 DKYIVTGSGDKKATVYEV 314
>12372
Length = 1287
Score = 30.8 bits (68), Expect = 1.6, Method: Compositional matrix adjust.
Identities = 16/43 (37%), Positives = 23/43 (53%)
Frame = +3
Query: 479 QAELVDEDAMSQIRKGHDTMCVVLTSRHKNLDTVRAVWTMGDI 521
+E +D++A Q R+ H + V + S KNL A W MG I
Sbjct: 252 HSEFLDKEACKQTRQEH--LPVHVASNDKNLSERGAAWNMGHI 374
>30176
Length = 365
Score = 30.8 bits (68), Expect = 1.8, Method: Composition-based stats.
Identities = 13/31 (41%), Positives = 18/31 (58%)
Frame = +2
Query: 144 RGHSQAVRCLRFSPDGKWLASAADDHTVKLW 174
+ H+ V L F G LAS +DD T+K+W
Sbjct: 11 KSHTSTVWNLTFDKTGTRLASCSDDKTIKIW 103
>20271
Length = 567
Score = 30.8 bits (68), Expect = 1.8, Method: Compositional matrix adjust.
Identities = 16/70 (22%), Positives = 31/70 (44%), Gaps = 6/70 (8%)
Frame = -1
Query: 185 FPGHTGPVNVVEFHPNEY------LLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVL 238
+ GH GP+ ++ H + S D T++ W++++ + V E V V
Sbjct: 297 YEGHQGPITAIDTHHAAGQIDFSPFFLTASFDWTVKLWNIKEQKYVCSFEDNSDYVSDVQ 118
Query: 239 FNPDGCCLYS 248
++P L+S
Sbjct: 117 WSPTNPALFS 88
>13509
Length = 572
Score = 30.4 bits (67), Expect = 2.4, Method: Compositional matrix adjust.
Identities = 16/52 (30%), Positives = 23/52 (44%)
Frame = +2
Query: 192 VNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVLFNPDG 243
VN + FHP L++ SD FWD + + E P+ + FN G
Sbjct: 368 VNDISFHPVHGTLSTVGSDGRFSFWDKDARTKLKTSEQFDQPITTCNFNAQG 523
>31054
Length = 392
Score = 30.0 bits (66), Expect = 3.0, Method: Compositional matrix adjust.
Identities = 19/71 (26%), Positives = 30/71 (42%)
Frame = -2
Query: 147 SQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLAS 206
S+AV SPD VK W G + GH +N + + ++ +L S
Sbjct: 382 SKAVHFAXGSPD-----------XVKQWKFPDGNFIQNLSGHNAIINTLAVN-SDGVLVS 239
Query: 207 GSSDRTIRFWD 217
G+ + T+ WD
Sbjct: 238 GADNGTMHLWD 206
>25930
Length = 419
Score = 29.3 bits (64), Expect = 4.7, Method: Compositional matrix adjust.
Identities = 20/90 (22%), Positives = 42/90 (46%)
Frame = +1
Query: 26 LVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSG 85
+ +G G +L D R+ W + + I G ++++ + +++ S+SG
Sbjct: 103 VAVGSVRGDILIY---DVRLEPWRLAR---IAPSNGQDDSIKNLNWSLDATRLISVSESG 264
Query: 86 SIRVWDLEAAKILRTLMGHKANICSLDFHP 115
+++VWDLE + +K + L+ HP
Sbjct: 265 TLQVWDLEGPAV------NKQDARLLELHP 336
>30727
Length = 402
Score = 29.3 bits (64), Expect = 5.9, Method: Compositional matrix adjust.
Identities = 20/65 (30%), Positives = 28/65 (43%), Gaps = 5/65 (7%)
Frame = +1
Query: 38 TGGDDCRVNLWSINKPNCI-----MSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDL 92
+GG D R+ W +KP C+ L TS + +N P +A + GSI L
Sbjct: 115 SGGMDSRLVHWDFSKPKCLNQFNMQELHSTTSDASAYMINPPFIHHLAKNSDGSIIACAL 294
Query: 93 EAAKI 97
E I
Sbjct: 295 ENGLI 309
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000380938 | hsapiens_gene_ensembl | Centrosomal
protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).
[Source:Uniprot/SWISSPROT;Acc:O15078]
(1906 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
16375 246 1e-75
37943 59 1e-08
>16375
Length = 1791
Score = 246 bits (627), Expect(2) = 1e-75, Method: Compositional matrix adjust.
Identities = 157/413 (38%), Positives = 234/413 (56%), Gaps = 13/413 (3%)
Frame = +3
Query: 768 AQKVINWHMKIEELRLQELKLNRELVKDKEEIKYLNNIISEYERTISSLEEEIVQQNKFH 827
A KV WH K++ LRL+ELK R K ++IKYL II +E +IS LEE+ V+ K
Sbjct: 3 ATKVAEWHSKMDALRLEELKQRRNNAKLHQQIKYLEEIIRSHEVSISELEEDNVRLLKGF 182
Query: 828 EERQMAWDQREVDLERQLDIFDRQQNEILNAAQKFEEATGSIPDPSLPLPNQLEIALRKI 887
EERQM W+QRE +LER + ++Q EI AA +FE+A GS+PD LP+ NQLE A+ I
Sbjct: 183 EERQMRWEQREGELERNILTMEKQTAEITGAAARFEQAIGSLPDAKLPVANQLEQAITTI 362
Query: 888 KENIRIILETRATCXXXXXXXXXXXXXXXXXXQNILSRDKVINELRLRLPATAEREKLI- 946
K N+++IL+T+A + ++ R+K+I+ELRLR+PAT +R+ +I
Sbjct: 363 KTNVKVILDTQAENKAYKSKINEMEKLLKDSERTVIEREKLISELRLRMPATTDRDTIIE 542
Query: 947 ------AELGRKEMEP--KSHHTLKIAHQTIANMQARLNQKEEVLKKYQRLLEKAREEQR 998
+E K EP ++H LKIA T+ ++Q R+ QKEE + KYQ LL++AR++
Sbjct: 543 RATAKVSEAMAKTSEPDYETHQGLKIAQSTVHSLQQRIQQKEETVVKYQELLKQARQDML 722
Query: 999 EIVKKHEEDLHILHHRLELQADSSLNKFKQTAWDLMKQSPT----PVPTNKHFIRLAEME 1054
++ ++HE++L + H++ +D + +KFKQ A +L+ Q T P + K RL E+E
Sbjct: 723 DMNRRHEQELKAMQHKVHQSSDIAFSKFKQAAQELLTQQSTTQRRPF-SEKQLERLTELE 899
Query: 1055 QTVAEXXXXXXXXXXXXXXXXXXXERQREITELKVKEFENIKLQLQENHEDXXXXXXXXX 1114
TVAE R R K + K +L++
Sbjct: 900 DTVAEQENTIAALHEKIKQKEEDVIRLRAEIATSQKHIKTEKHKLKQEQSSLQSQKNTEL 1079
Query: 1115 XDLKYLLDQSQKESQCLKSELQAQKEANSRAPTTTMRNLVERLKSQLALKEKQ 1167
DL+ ++ +KE + L E+ A K++ +R PT +M+NLVERLK QLALKEKQ
Sbjct: 1080 DDLQRVIGDQRKEIRVLNEEIDALKDSQARGPTASMKNLVERLKHQLALKEKQ 1238
Score = 57.8 bits (138), Expect(2) = 1e-75, Method: Compositional matrix adjust.
Identities = 46/172 (26%), Positives = 86/172 (50%), Gaps = 3/172 (1%)
Frame = +1
Query: 1182 MTAAAEERIISATSQKEAHLNVQQIVDRHTRELKTQVEDXXXXXXXXXXXXXTSKNRXXX 1241
M A A+ +++ + + NVQ+++D T++L Q+ED K
Sbjct: 1282 MVAQAQNNVVAQAEEAQQERNVQRLIDASTKDLTEQLEDMQSQLERAKRELKKRKESESL 1461
Query: 1242 XXXXXXXXXXXXQKKQKAYNKILREKEEIDQENDELKRQIKRLTSGLQGKPLTDNKQSLI 1301
+K++A+NK+ K +++ E DEL+++++RL++ K + +
Sbjct: 1462 LQTELEDTKEELSRKERAHNKLRNSKAKLETEVDELEKKVERLSTHKSQKTADFERMQEL 1641
Query: 1302 EELQRKVKKLENQLEGKVEEVDLKPMKEKNAK---EELIRWEEGKKWQAKIE 1350
E+++R+ + LE++L K KP ++K K EE +RWEE KKWQ I+
Sbjct: 1642 EDMRRRNRYLEDEL--KKRHTAEKPYEQKEDKTKTEEAMRWEESKKWQRTID 1791
>37943
Length = 588
Score = 59.3 bits (142), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 43/141 (30%), Positives = 69/141 (48%), Gaps = 3/141 (2%)
Frame = +1
Query: 186 VFKGIDLPDGIAPSSASIINSQNEYLIHXXXXXXXXXXXXXXXXDSLEDYNRKFAVIRHQ 245
V + + LP+G+AP+SA +I S NE+L+ +LE+Y RKF V+RHQ
Sbjct: 160 VTQAMALPEGMAPTSAEVIASLNEHLVIVLQELSQREEKMNKMEKALENYKRKFGVMRHQ 339
Query: 246 QSLLYKEYLSEKETWKTESKTIKEEKRKLEDQVQQDAIK---VKEYNNLLNALQMDSDEM 302
Q LLY+ + + T ++ Q + + + V A
Sbjct: 340 QGLLYQGLPA*QGGVGEGEGTSDQQAEGRSGQQRGGSCED**V**TGGHTEA--RRCRR* 513
Query: 303 KKILAENSRKITVLQVNEKSL 323
++ L+E +R+ITVL+VNEK+L
Sbjct: 514 RRRLSEMTRRITVLRVNEKAL 576
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000308021 | hsapiens_gene_ensembl | Centrosomal
protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).
[Source:Uniprot/SWISSPROT;Acc:O15078]
(2481 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
16375 246 2e-75
37943 59 2e-08
>16375
Length = 1791
Score = 246 bits (628), Expect(2) = 2e-75, Method: Compositional matrix adjust.
Identities = 157/413 (38%), Positives = 234/413 (56%), Gaps = 13/413 (3%)
Frame = +3
Query: 1343 AQKVINWHMKIEELRLQELKLNRELVKDKEEIKYLNNIISEYERTISSLEEEIVQQNKFH 1402
A KV WH K++ LRL+ELK R K ++IKYL II +E +IS LEE+ V+ K
Sbjct: 3 ATKVAEWHSKMDALRLEELKQRRNNAKLHQQIKYLEEIIRSHEVSISELEEDNVRLLKGF 182
Query: 1403 EERQMAWDQREVDLERQLDIFDRQQNEILNAAQKFEEATGSIPDPSLPLPNQLEIALRKI 1462
EERQM W+QRE +LER + ++Q EI AA +FE+A GS+PD LP+ NQLE A+ I
Sbjct: 183 EERQMRWEQREGELERNILTMEKQTAEITGAAARFEQAIGSLPDAKLPVANQLEQAITTI 362
Query: 1463 KENIRIILETRATCXXXXXXXXXXXXXXXXXXQNILSRDKVINELRLRLPATAEREKLI- 1521
K N+++IL+T+A + ++ R+K+I+ELRLR+PAT +R+ +I
Sbjct: 363 KTNVKVILDTQAENKAYKSKINEMEKLLKDSERTVIEREKLISELRLRMPATTDRDTIIE 542
Query: 1522 ------AELGRKEMEP--KSHHTLKIAHQTIANMQARLNQKEEVLKKYQRLLEKAREEQR 1573
+E K EP ++H LKIA T+ ++Q R+ QKEE + KYQ LL++AR++
Sbjct: 543 RATAKVSEAMAKTSEPDYETHQGLKIAQSTVHSLQQRIQQKEETVVKYQELLKQARQDML 722
Query: 1574 EIVKKHEEDLHILHHRLELQADSSLNKFKQTAWDLMKQSPT----PVPTNKHFIRLAEME 1629
++ ++HE++L + H++ +D + +KFKQ A +L+ Q T P + K RL E+E
Sbjct: 723 DMNRRHEQELKAMQHKVHQSSDIAFSKFKQAAQELLTQQSTTQRRPF-SEKQLERLTELE 899
Query: 1630 QTVAEXXXXXXXXXXXXXXXXXXXERQREITELKVKEFENIKLQLQENHEDXXXXXXXXX 1689
TVAE R R K + K +L++
Sbjct: 900 DTVAEQENTIAALHEKIKQKEEDVIRLRAEIATSQKHIKTEKHKLKQEQSSLQSQKNTEL 1079
Query: 1690 XDLKYLLDQSQKESQCLKSELQAQKEANSRAPTTTMRNLVERLKSQLALKEKQ 1742
DL+ ++ +KE + L E+ A K++ +R PT +M+NLVERLK QLALKEKQ
Sbjct: 1080 DDLQRVIGDQRKEIRVLNEEIDALKDSQARGPTASMKNLVERLKHQLALKEKQ 1238
Score = 57.8 bits (138), Expect(2) = 2e-75, Method: Compositional matrix adjust.
Identities = 46/172 (26%), Positives = 86/172 (50%), Gaps = 3/172 (1%)
Frame = +1
Query: 1757 MTAAAEERIISATSQKEAHLNVQQIVDRHTRELKTQVEDXXXXXXXXXXXXXTSKNRXXX 1816
M A A+ +++ + + NVQ+++D T++L Q+ED K
Sbjct: 1282 MVAQAQNNVVAQAEEAQQERNVQRLIDASTKDLTEQLEDMQSQLERAKRELKKRKESESL 1461
Query: 1817 XXXXXXXXXXXXQKKQKAYNKILREKEEIDQENDELKRQIKRLTSGLQGKPLTDNKQSLI 1876
+K++A+NK+ K +++ E DEL+++++RL++ K + +
Sbjct: 1462 LQTELEDTKEELSRKERAHNKLRNSKAKLETEVDELEKKVERLSTHKSQKTADFERMQEL 1641
Query: 1877 EELQRKVKKLENQLEGKVEEVDLKPMKEKNAK---EELIRWEEGKKWQAKIE 1925
E+++R+ + LE++L K KP ++K K EE +RWEE KKWQ I+
Sbjct: 1642 EDMRRRNRYLEDEL--KKRHTAEKPYEQKEDKTKTEEAMRWEESKKWQRTID 1791
>37943
Length = 588
Score = 59.3 bits (142), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 43/141 (30%), Positives = 69/141 (48%), Gaps = 3/141 (2%)
Frame = +1
Query: 761 VFKGIDLPDGIAPSSASIINSQNEYLIHXXXXXXXXXXXXXXXXDSLEDYNRKFAVIRHQ 820
V + + LP+G+AP+SA +I S NE+L+ +LE+Y RKF V+RHQ
Sbjct: 160 VTQAMALPEGMAPTSAEVIASLNEHLVIVLQELSQREEKMNKMEKALENYKRKFGVMRHQ 339
Query: 821 QSLLYKEYLSEKETWKTESKTIKEEKRKLEDQVQQDAIK---VKEYNNLLNALQMDSDEM 877
Q LLY+ + + T ++ Q + + + V A
Sbjct: 340 QGLLYQGLPA*QGGVGEGEGTSDQQAEGRSGQQRGGSCED**V**TGGHTEA--RRCRR* 513
Query: 878 KKILAENSRKITVLQVNEKSL 898
++ L+E +R+ITVL+VNEK+L
Sbjct: 514 RRRLSEMTRRITVLRVNEKAL 576
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000259335 | hsapiens_gene_ensembl |
Proteasome-associated protein ECM29 homolog (Ecm29).
[Source:Uniprot/SWISSPROT;Acc:Q5VYK3]
(1833 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
14383 275 1e-73
15971 270 4e-72
29563 69 2e-11
32022 36 0.13
18026 32 1.6
>14383
Length = 710
Score = 275 bits (702), Expect = 1e-73, Method: Compositional matrix adjust.
Identities = 134/225 (59%), Positives = 171/225 (76%), Gaps = 1/225 (0%)
Frame = +2
Query: 1087 KGAAFGFNVIATRAGEQLAPFLPQLVPRLYRYQFDPNLGIRQAMTSIWNALVTD-KSMVD 1145
KG F+ T + EQLAP++ Q+VPRLYRYQFDPN I+QAM IW+ALVTD K VD
Sbjct: 2 KGQRLDFHDCYT-SREQLAPYMSQIVPRLYRYQFDPNPRIQQAMAGIWSALVTDNKKTVD 178
Query: 1146 KYLKEILQDLVKNLTSNMWRVRESSCLALNDLLRGRPLDDIIDKLPEIWETLFRVQDDIK 1205
YLKEIL DL+KNLT+N WRVRESSC A+ DLLRGR LD I++ LPE+WE RV+DDIK
Sbjct: 179 TYLKEILHDLLKNLTNNQWRVRESSCNAVTDLLRGRTLDTIVEDLPELWEQCLRVRDDIK 358
Query: 1206 ESVRKAAELALKTLSKVCVKMCDPAKGAAGQRTIAALLPCLLDKGMMSTVTEVRALSINT 1265
ESVR +A+ + KTLSKV +++CDP G AG+R +A+LPCLL+ + + V EVRA+ ++T
Sbjct: 359 ESVRLSADQSCKTLSKVSIRICDPENGQAGERATSAVLPCLLNITLNTNVKEVRAIGLST 538
Query: 1266 LVKISKSAGAMLKPHAPKLIPALLESLSVLEPQVLNYLSLRATEQ 1310
+++ISK AG +LKPH L+ ALLE++S LEPQVLNYLS + Q
Sbjct: 539 ILEISKKAGKLLKPHIHTLVVALLEAVSGLEPQVLNYLSFHTSSQ 673
>15971
Length = 742
Score = 270 bits (690), Expect = 4e-72, Method: Compositional matrix adjust.
Identities = 130/247 (52%), Positives = 179/247 (72%), Gaps = 2/247 (0%)
Frame = -1
Query: 1235 GQRTIAALLPCLLDKGMMSTVTEVRALSINTLVKISKSAGAMLKPHAPKLIPALLESLSV 1294
G+R +A+LPCLL+ + + V EVRA+ ++T+++ISK AG +LKPH L+ ALLE++S
Sbjct: 742 GERATSAVLPCLLNITLNTNVKEVRAIGLSTILEISKKAGKLLKPHIHTLVVALLEAVSG 563
Query: 1295 LEPQVLNYLSLRATEQ-EKAAMDSA-RLSAAKSSPMMETINMCLQYLDVSVLGELVPRLC 1352
LEPQVLNYLS + Q + +D A R A+KSSPMMET+N C+QY+D SVL ELVPRL
Sbjct: 562 LEPQVLNYLSFHTSSQVTQDKLDKAHRG*ASKSSPMMETVNRCVQYVDESVLTELVPRLT 383
Query: 1353 ELIRSGVGLGTKGGCASVIVSLTTQCPQDLTPYSGKLMSALLSGLTDRNSVIQKSCAFAM 1412
ELI+ G+G+GTK GC+S +VSL QCP DL P++GKLM A L GL DRNS ++K+ A A+
Sbjct: 382 ELIKRGLGVGTKAGCSSFVVSLVHQCPHDLAPHAGKLMGAFLHGLNDRNSSVRKNYASAL 203
Query: 1413 GHLVRTSRDSSTEKLLQKLNGWYMEKEEPIYKTSCALTIHAIGRYSPDVLKNHAKEVLPL 1472
HLV+ +D STEKL+ KL WY++ E + +C +T+HAI + +PD L+ HA +PL
Sbjct: 202 AHLVKVGKDKSTEKLICKLKTWYLDHENESAQQACGVTLHAISQTAPDHLRRHASLAMPL 23
Query: 1473 AFLGMHE 1479
AF +H+
Sbjct: 22 AFFALHQ 2
>29563
Length = 1310
Score = 68.9 bits (167), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 31/43 (72%), Positives = 38/43 (88%)
Frame = +1
Query: 4 LERVFLRLGHAETDEQLQNIISKFLPPVLLKLSSTQEGVRKKV 46
+ERVFLR G AETDEQL+N++ KFL PVLLKL+S++E VRKKV
Sbjct: 1042 VERVFLRFGSAETDEQLENVLGKFLAPVLLKLNSSEEAVRKKV 1170
>32022
Length = 498
Score = 36.2 bits (82), Expect = 0.13, Method: Composition-based stats.
Identities = 26/79 (32%), Positives = 39/79 (49%)
Frame = -1
Query: 1149 KEILQDLVKNLTSNMWRVRESSCLALNDLLRGRPLDDIIDKLPEIWETLFRVQDDIKESV 1208
K+ + LV L VRES+CL+L L + +D I+D R ++D +V
Sbjct: 342 KDTVPRLVSLLEDEDRLVRESACLSLGFLQATKAVDHIVD----------RWRNDPISTV 193
Query: 1209 RKAAELALKTLSKVCVKMC 1227
R+AAELAL + + C
Sbjct: 192 REAAELALSKMKIAEAQRC 136
>18026
Length = 628
Score = 32.3 bits (72), Expect = 1.6, Method: Composition-based stats.
Identities = 17/40 (42%), Positives = 21/40 (52%)
Frame = -1
Query: 1415 LVRTSRDSSTEKLLQKLNGWYMEKEEPIYKTSCALTIHAI 1454
+ R S +S T K L+ LNG + P YK C LT AI
Sbjct: 181 MARASENSHTNKPLKLLNGSHGPHTMPTYKVFCCLTNQAI 62
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000339889 | hsapiens_gene_ensembl |
Proteasome-associated protein ECM29 homolog (Ecm29).
[Source:Uniprot/SWISSPROT;Acc:Q5VYK3]
(1839 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
14383 275 2e-73
15971 270 4e-72
29563 69 2e-11
32022 36 0.14
18026 32 1.6
>14383
Length = 710
Score = 275 bits (702), Expect = 2e-73, Method: Compositional matrix adjust.
Identities = 134/225 (59%), Positives = 171/225 (76%), Gaps = 1/225 (0%)
Frame = +2
Query: 1093 KGAAFGFNVIATRAGEQLAPFLPQLVPRLYRYQFDPNLGIRQAMTSIWNALVTD-KSMVD 1151
KG F+ T + EQLAP++ Q+VPRLYRYQFDPN I+QAM IW+ALVTD K VD
Sbjct: 2 KGQRLDFHDCYT-SREQLAPYMSQIVPRLYRYQFDPNPRIQQAMAGIWSALVTDNKKTVD 178
Query: 1152 KYLKEILQDLVKNLTSNMWRVRESSCLALNDLLRGRPLDDIIDKLPEIWETLFRVQDDIK 1211
YLKEIL DL+KNLT+N WRVRESSC A+ DLLRGR LD I++ LPE+WE RV+DDIK
Sbjct: 179 TYLKEILHDLLKNLTNNQWRVRESSCNAVTDLLRGRTLDTIVEDLPELWEQCLRVRDDIK 358
Query: 1212 ESVRKAAELALKTLSKVCVKMCDPAKGAAGQRTIAALLPCLLDKGMMSTVTEVRALSINT 1271
ESVR +A+ + KTLSKV +++CDP G AG+R +A+LPCLL+ + + V EVRA+ ++T
Sbjct: 359 ESVRLSADQSCKTLSKVSIRICDPENGQAGERATSAVLPCLLNITLNTNVKEVRAIGLST 538
Query: 1272 LVKISKSAGAMLKPHAPKLIPALLESLSVLEPQVLNYLSLRATEQ 1316
+++ISK AG +LKPH L+ ALLE++S LEPQVLNYLS + Q
Sbjct: 539 ILEISKKAGKLLKPHIHTLVVALLEAVSGLEPQVLNYLSFHTSSQ 673
>15971
Length = 742
Score = 270 bits (690), Expect = 4e-72, Method: Compositional matrix adjust.
Identities = 130/247 (52%), Positives = 179/247 (72%), Gaps = 2/247 (0%)
Frame = -1
Query: 1241 GQRTIAALLPCLLDKGMMSTVTEVRALSINTLVKISKSAGAMLKPHAPKLIPALLESLSV 1300
G+R +A+LPCLL+ + + V EVRA+ ++T+++ISK AG +LKPH L+ ALLE++S
Sbjct: 742 GERATSAVLPCLLNITLNTNVKEVRAIGLSTILEISKKAGKLLKPHIHTLVVALLEAVSG 563
Query: 1301 LEPQVLNYLSLRATEQ-EKAAMDSA-RLSAAKSSPMMETINMCLQYLDVSVLGELVPRLC 1358
LEPQVLNYLS + Q + +D A R A+KSSPMMET+N C+QY+D SVL ELVPRL
Sbjct: 562 LEPQVLNYLSFHTSSQVTQDKLDKAHRG*ASKSSPMMETVNRCVQYVDESVLTELVPRLT 383
Query: 1359 ELIRSGVGLGTKGGCASVIVSLTTQCPQDLTPYSGKLMSALLSGLTDRNSVIQKSCAFAM 1418
ELI+ G+G+GTK GC+S +VSL QCP DL P++GKLM A L GL DRNS ++K+ A A+
Sbjct: 382 ELIKRGLGVGTKAGCSSFVVSLVHQCPHDLAPHAGKLMGAFLHGLNDRNSSVRKNYASAL 203
Query: 1419 GHLVRTSRDSSTEKLLQKLNGWYMEKEEPIYKTSCALTIHAIGRYSPDVLKNHAKEVLPL 1478
HLV+ +D STEKL+ KL WY++ E + +C +T+HAI + +PD L+ HA +PL
Sbjct: 202 AHLVKVGKDKSTEKLICKLKTWYLDHENESAQQACGVTLHAISQTAPDHLRRHASLAMPL 23
Query: 1479 AFLGMHE 1485
AF +H+
Sbjct: 22 AFFALHQ 2
>29563
Length = 1310
Score = 68.9 bits (167), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 31/43 (72%), Positives = 38/43 (88%)
Frame = +1
Query: 10 LERVFLRLGHAETDEQLQNIISKFLPPVLLKLSSTQEGVRKKV 52
+ERVFLR G AETDEQL+N++ KFL PVLLKL+S++E VRKKV
Sbjct: 1042 VERVFLRFGSAETDEQLENVLGKFLAPVLLKLNSSEEAVRKKV 1170
>32022
Length = 498
Score = 36.2 bits (82), Expect = 0.14, Method: Composition-based stats.
Identities = 26/79 (32%), Positives = 39/79 (49%)
Frame = -1
Query: 1155 KEILQDLVKNLTSNMWRVRESSCLALNDLLRGRPLDDIIDKLPEIWETLFRVQDDIKESV 1214
K+ + LV L VRES+CL+L L + +D I+D R ++D +V
Sbjct: 342 KDTVPRLVSLLEDEDRLVRESACLSLGFLQATKAVDHIVD----------RWRNDPISTV 193
Query: 1215 RKAAELALKTLSKVCVKMC 1233
R+AAELAL + + C
Sbjct: 192 REAAELALSKMKIAEAQRC 136
>18026
Length = 628
Score = 32.3 bits (72), Expect = 1.6, Method: Composition-based stats.
Identities = 17/40 (42%), Positives = 21/40 (52%)
Frame = -1
Query: 1421 LVRTSRDSSTEKLLQKLNGWYMEKEEPIYKTSCALTIHAI 1460
+ R S +S T K L+ LNG + P YK C LT AI
Sbjct: 181 MARASENSHTNKPLKLLNGSHGPHTMPTYKVFCCLTNQAI 62
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000272298 | hsapiens_gene_ensembl | Calmodulin
(CaM). [Source:Uniprot/SWISSPROT;Acc:P62158]
(149 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
14594 269 3e-73
14366 140 2e-34
22063 105 9e-34
14945 105 1e-33
38338 134 1e-32
05237 132 4e-32
20251 117 2e-27
01019 115 8e-27
26610 109 5e-25
17484 83 4e-24
18171 100 2e-22
06641 99 6e-22
01491 68 9e-20
11425 91 1e-19
16255 78 1e-15
07385 72 6e-14
19942 64 2e-11
08108 63 4e-11
26019 62 7e-11
01773 59 8e-10
22273 56 6e-09
04067 51 1e-07
07678 51 2e-07
15966 48 1e-06
17892 48 2e-06
04697 48 2e-06
19912 44 2e-05
07198 44 2e-05
04643 44 3e-05
26849 44 4e-05
00167 43 4e-05
32088 43 5e-05
05230 39 0.001
13028 39 0.001
17977 38 0.001
03616 36 0.005
08380 35 0.010
18677 35 0.014
35350 33 0.036
28617 33 0.048
22490 32 0.15
28023 31 0.22
01130 30 0.28
15239 28 1.2
30885 28 1.4
12671 28 2.0
13551 27 2.2
05818 27 3.8
33397 26 5.2
>14594
Length = 1014
Score = 269 bits (688), Expect = 3e-73, Method: Compositional matrix adjust.
Identities = 133/145 (91%), Positives = 138/145 (95%)
Frame = +3
Query: 5 LTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTI 64
LT+EQ+AEFKEAFSLFDKDGDGTITT ELGTVMRSLGQNPTE ELQDMINEVDADGNGTI
Sbjct: 423 LTDEQVAEFKEAFSLFDKDGDGTITTSELGTVMRSLGQNPTENELQDMINEVDADGNGTI 602
Query: 65 DFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDE 124
DF EFL MMARKMKDTD EEE+REAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDE
Sbjct: 603 DFEEFLHMMARKMKDTDCEEELREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDE 782
Query: 125 MIREADIDGDGQVNYEEFVQMMTAK 149
MI+EAD+DGDG VNYEEFV MMTAK
Sbjct: 783 MIKEADLDGDGMVNYEEFVTMMTAK 857
>14366
Length = 499
Score = 140 bits (353), Expect = 2e-34, Method: Compositional matrix adjust.
Identities = 71/143 (49%), Positives = 103/143 (72%)
Frame = -3
Query: 4 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGT 63
QL +E E +EAF + + D TI +LG V+RS+G+ PTE++L+ + E + G T
Sbjct: 479 QLRQE---ELQEAF-IMNCSPDNTIALNKLGIVVRSIGRAPTESQLKTLTMEFENRGKRT 312
Query: 64 IDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVD 123
+ E + ++ + ++ + +REAFR+FDK+GNG I+AAELRHV+T+LGEKL+DEEVD
Sbjct: 311 LTLQEVIAIVTKYEFAPETSDNLREAFRIFDKEGNGMINAAELRHVLTHLGEKLSDEEVD 132
Query: 124 EMIREADIDGDGQVNYEEFVQMM 146
EMIREADI GDGQV+Y +FV++M
Sbjct: 131 EMIREADISGDGQVSYNDFVKVM 63
>22063
Length = 688
Score = 105 bits (263), Expect(2) = 9e-34, Method: Compositional matrix adjust.
Identities = 53/96 (55%), Positives = 69/96 (71%)
Frame = +3
Query: 4 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGT 63
+LTEEQ E +EAF LFD DG GTI KEL MR+LG P + E++ MI E+D +G GT
Sbjct: 150 ELTEEQKQEIREAFDLFDADGSGTIDAKELKVAMRALGFEPKKEEIKKMIAEIDKEGTGT 329
Query: 64 IDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNG 99
IDF +FLT+M +KM + D++EEI +AFR+FD D G
Sbjct: 330 IDFNDFLTIMTQKMSEKDAKEEILKAFRLFDDDETG 437
Score = 53.5 bits (127), Expect(2) = 9e-34, Method: Compositional matrix adjust.
Identities = 27/46 (58%), Positives = 34/46 (73%)
Frame = +1
Query: 101 ISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 146
IS L+ V LGE LTDEE+ EMI EAD DGDG++N EEF+++M
Sbjct: 442 ISFRNLKRVAKELGENLTDEELQEMIDEADRDGDGEINQEEFLRIM 579
Score = 59.7 bits (143), Expect = 5e-10, Method: Compositional matrix adjust.
Identities = 30/69 (43%), Positives = 46/69 (66%)
Frame = +3
Query: 81 DSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYE 140
+ ++EIREAF +FD DG+G I A EL+ M LG + EE+ +MI E D +G G +++
Sbjct: 162 EQKQEIREAFDLFDADGSGTIDAKELKVAMRALGFEPKKEEIKKMIAEIDKEGTGTIDFN 341
Query: 141 EFVQMMTAK 149
+F+ +MT K
Sbjct: 342 DFLTIMTQK 368
Score = 45.8 bits (107), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 22/50 (44%), Positives = 33/50 (66%)
Frame = +1
Query: 26 GTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMAR 75
I+ + L V + LG+N T+ ELQ+MI+E D DG+G I+ EFL +M +
Sbjct: 436 AKISFRNLKRVAKELGENLTDEELQEMIDEADRDGDGEINQEEFLRIMKK 585
>14945
Length = 1337
Score = 105 bits (262), Expect(2) = 1e-33, Method: Compositional matrix adjust.
Identities = 53/96 (55%), Positives = 69/96 (71%)
Frame = +1
Query: 4 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGT 63
+LTEEQ E +EAF LFD DG GTI KEL MR+LG P + E++ MI E+D +G GT
Sbjct: 91 ELTEEQKQEIREAFDLFDADGSGTIDAKELKVAMRALGFEPKKEEIKKMIAEIDKEGTGT 270
Query: 64 IDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNG 99
IDF +FLT+M +KM + D++EEI +AFR+FD D G
Sbjct: 271 IDFNDFLTIMTQKMSEKDAKEEILKAFRLFDDDETG 378
Score = 53.5 bits (127), Expect(2) = 1e-33, Method: Compositional matrix adjust.
Identities = 27/46 (58%), Positives = 34/46 (73%)
Frame = +2
Query: 101 ISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 146
IS L+ V LGE LTDEE+ EMI EAD DGDG++N EEF+++M
Sbjct: 383 ISFRNLKRVAKELGENLTDEELQEMIDEADRDGDGEINQEEFLRIM 520
Score = 60.5 bits (145), Expect = 3e-10, Method: Compositional matrix adjust.
Identities = 30/69 (43%), Positives = 46/69 (66%)
Frame = +1
Query: 81 DSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYE 140
+ ++EIREAF +FD DG+G I A EL+ M LG + EE+ +MI E D +G G +++
Sbjct: 103 EQKQEIREAFDLFDADGSGTIDAKELKVAMRALGFEPKKEEIKKMIAEIDKEGTGTIDFN 282
Query: 141 EFVQMMTAK 149
+F+ +MT K
Sbjct: 283 DFLTIMTQK 309
Score = 45.8 bits (107), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 22/50 (44%), Positives = 33/50 (66%)
Frame = +2
Query: 26 GTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMAR 75
I+ + L V + LG+N T+ ELQ+MI+E D DG+G I+ EFL +M +
Sbjct: 377 AKISFRNLKRVAKELGENLTDEELQEMIDEADRDGDGEINQEEFLRIMKK 526
Score = 37.7 bits (86), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 30/90 (33%), Positives = 46/90 (51%), Gaps = 1/90 (1%)
Frame = +1
Query: 48 ELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELR 107
E+++ + DADG+GTID E M R + +EEI++ DK+G G I +
Sbjct: 115 EIREAFDLFDADGSGTIDAKELKVAM-RALGFEPKKEEIKKMIAEIDKEGTGTIDFNDFL 291
Query: 108 HVMT-NLGEKLTDEEVDEMIREADIDGDGQ 136
+MT + EK EE+ + R D D G+
Sbjct: 292 TIMTQKMSEKDAKEEILKAFRLFDDDETGK 381
>38338
Length = 463
Score = 134 bits (337), Expect = 1e-32, Method: Compositional matrix adjust.
Identities = 66/66 (100%), Positives = 66/66 (100%)
Frame = -2
Query: 1 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADG 60
MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADG
Sbjct: 198 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADG 19
Query: 61 NGTIDF 66
NGTIDF
Sbjct: 18 NGTIDF 1
Score = 58.5 bits (140), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 31/72 (43%), Positives = 46/72 (63%), Gaps = 3/72 (4%)
Frame = -2
Query: 71 TMMARKMKDTDSEEEI---REAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIR 127
T M D +EE+I +EAF +FDKDG+G I+ EL VM +LG+ T+ E+ +MI
Sbjct: 216 THSKSNMADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMIN 37
Query: 128 EADIDGDGQVNY 139
E D DG+G +++
Sbjct: 36 EVDADGNGTIDF 1
>05237
Length = 472
Score = 132 bits (333), Expect = 4e-32, Method: Compositional matrix adjust.
Identities = 63/72 (87%), Positives = 71/72 (98%)
Frame = +3
Query: 78 KDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQV 137
K+TD+++E+REAFRVFDKDGNG+ISA+ELRHVMTNLGEKLTDEEVDEMIREADIDGDGQV
Sbjct: 9 KETDTDDELREAFRVFDKDGNGFISASELRHVMTNLGEKLTDEEVDEMIREADIDGDGQV 188
Query: 138 NYEEFVQMMTAK 149
NYEEFV+MMT K
Sbjct: 189 NYEEFVKMMTTK 224
Score = 66.2 bits (160), Expect = 5e-12, Method: Compositional matrix adjust.
Identities = 31/65 (47%), Positives = 45/65 (69%)
Frame = +3
Query: 12 EFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLT 71
E +EAF +FDKDG+G I+ EL VM +LG+ T+ E+ +MI E D DG+G +++ EF+
Sbjct: 30 ELREAFRVFDKDGNGFISASELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVK 209
Query: 72 MMARK 76
MM K
Sbjct: 210MMTTK 224
>20251
Length = 2203
Score = 117 bits (292), Expect = 2e-27, Method: Compositional matrix adjust.
Identities = 62/140 (44%), Positives = 91/140 (65%)
Frame = +3
Query: 7 EEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDF 66
+ QI EFKEAF++ D++ DG I ++LG ++ SLG+NPTE +L +M+N G I+F
Sbjct: 147 QSQIQEFKEAFNMIDQNRDGFIDKEDLGDMLASLGKNPTEGQLDEMMNXAP----GPINF 314
Query: 67 PEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMI 126
FLTM K+ TD E+ I+ AF FD+DG G I LR ++T +G++ TD+EVDEM
Sbjct: 315 TMFLTMFGDKLNGTDPEDVIKNAFACFDEDGKGVIQEDRLRELLTTMGDRFTDDEVDEMF 494
Query: 127 READIDGDGQVNYEEFVQMM 146
R+A I G +Y EF +++
Sbjct: 495 RDAPIKR-GNFDYLEFTRIL 551
Score = 39.3 bits (90), Expect = 6e-04, Method: Compositional matrix adjust.
Identities = 22/73 (30%), Positives = 41/73 (56%)
Frame = +3
Query: 77 MKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQ 136
M D +E +EAF + D++ +G+I +L ++ +LG+ T+ ++DEM+ A G
Sbjct: 138 MFDQSQIQEFKEAFNMIDQNRDGFIDKEDLGDMLASLGKNPTEGQLDEMMNXA----PGP 305
Query: 137 VNYEEFVQMMTAK 149
+N+ F+ M K
Sbjct: 306 INFTMFLTMFGDK 344
>01019
Length = 1705
Score = 115 bits (288), Expect = 8e-27, Method: Compositional matrix adjust.
Identities = 55/58 (94%), Positives = 57/58 (98%)
Frame = +1
Query: 92 VFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK 149
VFDKDGNG+ISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFV MMT+K
Sbjct: 43 VFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVTMMTSK 216
Score = 59.3 bits (142), Expect = 6e-10, Method: Compositional matrix adjust.
Identities = 28/58 (48%), Positives = 41/58 (70%)
Frame = +1
Query: 19 LFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARK 76
+FDKDG+G I+ EL VM +LG+ T+ E+ +MI E D DG+G +++ EF+TMM K
Sbjct: 43 VFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVTMMTSK 216
>26610
Length = 455
Score = 109 bits (272), Expect = 5e-25, Method: Compositional matrix adjust.
Identities = 48/133 (36%), Positives = 91/133 (68%)
Frame = +3
Query: 15 EAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMA 74
EAF LFD D DG I E+GT +RSLG T+++L+ ++++ + +G +D F +
Sbjct: 54 EAFELFDTDNDGKIAASEVGTAIRSLGHVVTDSDLRRLLSKAGIEPHGKVDMNRF-RQLV 230
Query: 75 RKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGD 134
+ ++ + +++ EAF DK+G+G++ A ELRH++T++G+++TDEE + ++ E ++D +
Sbjct: 231 QPLQGVNYTKQLDEAFNTIDKEGSGFVMATELRHLLTHMGDRITDEEFNALLEELEVDSN 410
Query: 135 GQVNYEEFVQMMT 147
G+V +EFVQ+++
Sbjct: 411 GRVRRKEFVQLLS 449
Score = 46.6 bits (109), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 21/65 (32%), Positives = 42/65 (64%)
Frame = +3
Query: 82 SEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEE 141
S++ + EAF +FD D +G I+A+E+ + +LG +TD ++ ++ +A I+ G+V+
Sbjct: 36 SKDAVSEAFELFDTDNDGKIAASEVGTAIRSLGHVVTDSDLRRLLSKAGIEPHGKVDMNR 215
Query: 142 FVQMM 146
F Q++
Sbjct: 216 FRQLV 230
Score = 42.4 bits (98), Expect = 7e-05, Method: Compositional matrix adjust.
Identities = 19/64 (29%), Positives = 36/64 (56%)
Frame = +3
Query: 12 EFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLT 71
+ EAF+ DK+G G + EL ++ +G T+ E ++ E++ D NG + EF+
Sbjct: 261 QLDEAFNTIDKEGSGFVMATELRHLLTHMGDRITDEEFNALLEELEVDSNGRVRRKEFVQ 440
Query: 72 MMAR 75
+++R
Sbjct: 441 LLSR 452
>17484
Length = 471
Score = 82.8 bits (203), Expect(2) = 4e-24, Method: Compositional matrix adjust.
Identities = 38/83 (45%), Positives = 61/83 (73%), Gaps = 1/83 (1%)
Frame = -3
Query: 68 EFLTMMARKMKD-TDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMI 126
EFL ++ +MK ++ ++E+R+AFR FD++G+G IS +ELR M +G+KL+D +V+ +I
Sbjct: 322 EFLPLIVGRMKGGSEKDKEMRDAFRAFDQNGDGVISISELRQAMAKMGQKLSDADVESII 143
Query: 127 READIDGDGQVNYEEFVQMMTAK 149
R+ D DGDG VNYEEF + + +
Sbjct: 142 RDVDKDGDGFVNYEEFTKFIAGQ 74
Score = 44.7 bits (104), Expect(2) = 4e-24, Method: Compositional matrix adjust.
Identities = 19/47 (40%), Positives = 31/47 (65%)
Frame = -1
Query: 20 FDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDF 66
+D+DG+G IT E +V+R LG + +E EL++M+ D D +G I+
Sbjct: 465 YDQDGNGKITRNEFRSVVRMLGHSLSEKELEEMMQAADTDASGAIEL 325
Score = 55.8 bits (133), Expect = 6e-09, Method: Compositional matrix adjust.
Identities = 25/67 (37%), Positives = 44/67 (65%)
Frame = -3
Query: 8 EQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFP 67
E+ E ++AF FD++GDG I+ EL M +GQ ++A+++ +I +VD DG+G +++
Sbjct: 280 EKDKEMRDAFRAFDQNGDGVISISELRQAMAKMGQKLSDADVESIIRDVDKDGDGFVNYE 101
Query: 68 EFLTMMA 74
EF +A
Sbjct: 100 EFTKFIA 80
Score = 43.9 bits (102), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 19/45 (42%), Positives = 31/45 (68%)
Frame = -1
Query: 93 FDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQV 137
+D+DGNG I+ E R V+ LG L+++E++EM++ AD D G +
Sbjct: 465 YDQDGNGKITRNEFRSVVRMLGHSLSEKELEEMMQAADTDASGAI 331
>18171
Length = 1131
Score = 100 bits (249), Expect = 2e-22, Method: Compositional matrix adjust.
Identities = 49/98 (50%), Positives = 70/98 (71%), Gaps = 3/98 (3%)
Frame = +3
Query: 52 MINEVDADGNGTIDFPEFLTMMARKMKDTDSEEE---IREAFRVFDKDGNGYISAAELRH 108
+I++V G +DFP+FLT+MAR + D +EE + EA + DKD G IS A LRH
Sbjct: 60 LIHDVSNSNQGKVDFPDFLTLMARTVGSKDPQEEDDAMLEALTLLDKDQTGVISTALLRH 239
Query: 109 VMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 146
V+T LG++LT EEV+E+I+EAD + GQV+Y+EF++MM
Sbjct: 240 VLTTLGDQLTSEEVEELIKEADKEETGQVDYKEFIKMM 353
>06641
Length = 726
Score = 99.0 bits (245), Expect = 6e-22, Method: Compositional matrix adjust.
Identities = 52/138 (37%), Positives = 84/138 (60%), Gaps = 5/138 (3%)
Frame = +1
Query: 16 AFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEV-DADGNGTIDFPEFLTMMA 74
AF +FD + + T+ +E+GT++RSLG P+EAEL DM+ E+ + + G I F +FL MM
Sbjct: 208 AFDIFDHEANKTVDVREVGTIIRSLGCCPSEAELHDMLAEIEEEEPTGYIRFEKFLPMMT 387
Query: 75 RKMKDTD----SEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREAD 130
+ + + E++I +AF+V D +G GY+ EL MT GE T EE++EM+ +A
Sbjct: 388 KVLMERRYKAVPEDQIVKAFQVLDVEGRGYLLQEELSKYMTEEGEPFTSEELEEMMSQAL 567
Query: 131 IDGDGQVNYEEFVQMMTA 148
G + Y+++ +M A
Sbjct: 568 DPEKGYIPYKDYASLMAA 621
>01491
Length = 1707
Score = 68.2 bits (165), Expect(2) = 9e-20, Method: Compositional matrix adjust.
Identities = 39/99 (39%), Positives = 62/99 (62%)
Frame = +1
Query: 50 QDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHV 109
++ + VD D G I + +F + K+ + + E E+REAFRV DK G I +LR +
Sbjct: 244 EEWADAVDEDAAGFITWEQFKPVFELKLHEDEDEREMREAFRVLDKGNKGVIPVEDLRWL 423
Query: 110 MTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTA 148
+ +LG+ LT++E+++MI E D DG G V+YEEF +M +
Sbjct: 424 LKSLGDDLTEDEIEDMIVETDTDGSGTVDYEEFRTLMNS 540
Score = 44.3 bits (103), Expect(2) = 9e-20, Method: Compositional matrix adjust.
Identities = 19/38 (50%), Positives = 27/38 (71%)
Frame = +2
Query: 4 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLG 41
Q+TE+ + + F LFDK G+GT++TKEL V +SLG
Sbjct: 107 QITEKMYNDASQTFHLFDKKGNGTVSTKELANVFKSLG 220
Score = 57.0 bits (136), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 27/58 (46%), Positives = 40/58 (68%)
Frame = +1
Query: 16 AFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMM 73
AF + DK G I ++L +++SLG + TE E++DMI E D DG+GT+D+ EF T+M
Sbjct: 361 AFRVLDKGNKGVIPVEDLRWLLKSLGDDLTEDEIEDMIVETDTDGSGTVDYEEFRTLM 534
Score = 35.4 bits (80), Expect = 0.009, Method: Compositional matrix adjust.
Identities = 15/35 (42%), Positives = 24/35 (68%)
Frame = +2
Query: 88 EAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEV 122
+ F +FDK GNG +S EL +V +LG ++ DE++
Sbjct: 140 QTFHLFDKKGNGTVSTKELANVFKSLGLQVEDEKL 244
>11425
Length = 599
Score = 91.3 bits (225), Expect = 1e-19, Method: Compositional matrix adjust.
Identities = 60/150 (40%), Positives = 87/150 (58%), Gaps = 9/150 (6%)
Frame = -2
Query: 4 QLTEEQIAEFKEAFSLFD-KDG-DGTITTKELGTVMRSLGQNPTEAELQDMINEVDAD-- 59
L++ I + E F LFD DG DG + ++G + LG NPT Q++I +
Sbjct: 580 SLSKSDIEDITEVFELFDFWDGRDGDVDAFKVGDMCFCLGLNPT----QEIIRKNGGTTK 413
Query: 60 -GNGTIDFPEFLTMM--ARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEK 116
G EFL + K KDT + + E F+ FD++G G+ISAAELRH++T LGE+
Sbjct: 412 LGEKAYKLEEFLPIYETISKEKDTGTFADFMEGFKTFDREGQGFISAAELRHLLTGLGER 233
Query: 117 LTDEEVDEMIREADI--DGDGQVNYEEFVQ 144
L+D+EVDE+I+ D D +G V YE+F+Q
Sbjct: 232 LSDDEVDELIKATDTREDLEGNVKYEDFIQ 143
>16255
Length = 767
Score = 78.2 bits (191), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 38/40 (95%), Positives = 39/40 (97%)
Frame = -2
Query: 110 MTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK 149
MTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFV MMT+K
Sbjct: 766 MTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVTMMTSK 647
Score = 41.2 bits (95), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 18/40 (45%), Positives = 28/40 (70%)
Frame = -2
Query: 37 MRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARK 76
M +LG+ T+ E+ +MI E D DG+G +++ EF+TMM K
Sbjct: 766 MTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVTMMTSK 647
>07385
Length = 1292
Score = 72.4 bits (176), Expect = 6e-14, Method: Compositional matrix adjust.
Identities = 37/49 (75%), Positives = 40/49 (81%)
Frame = +3
Query: 101 ISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK 149
ISA +LR +KLTDEEVDEMIREADIDGDGQVNYEEFV+MMT K
Sbjct: 114 ISAGQLRGARF---QKLTDEEVDEMIREADIDGDGQVNYEEFVKMMTTK 251
>19942
Length = 367
Score = 64.3 bits (155), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 31/32 (96%), Positives = 32/32 (100%)
Frame = +2
Query: 109 VMTNLGEKLTDEEVDEMIREADIDGDGQVNYE 140
VMTNLGEKLTDEEVDEMIREADIDGDGQVNY+
Sbjct: 2 VMTNLGEKLTDEEVDEMIREADIDGDGQVNYD 97
>08108
Length = 818
Score = 63.2 bits (152), Expect = 4e-11, Method: Compositional matrix adjust.
Identities = 42/139 (30%), Positives = 72/139 (51%), Gaps = 4/139 (2%)
Frame = +2
Query: 11 AEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFL 70
AE + AF++FD DG G+I+ ELG +R+ G + T+ + ++I + D+D NG ID EF
Sbjct: 125 AECQTAFAVFDTDGSGSISAGELGEALRAQGADITDDQTAELIKKYDSDSNGDIDTDEF- 301
Query: 71 TMMARKMKDTDSE----EEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMI 126
RK+ + +S+ + F+ D DG+G I+A+E+ TD + M+
Sbjct: 302 ----RKLVEGESDVARLAQSALMFKSLDADGDGQITASEITEAQGKKTIGATDGQFAAMV 469
Query: 127 READIDGDGQVNYEEFVQM 145
A G + + F++
Sbjct: 470 EAA---AGGVLTFAAFLKC 517
Score = 52.8 bits (125), Expect = 6e-08, Method: Compositional matrix adjust.
Identities = 24/65 (36%), Positives = 42/65 (64%)
Frame = +2
Query: 82 SEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEE 141
++ E + AF VFD DG+G ISA EL + G +TD++ E+I++ D D +G ++ +E
Sbjct: 119 TDAECQTAFAVFDTDGSGSISAGELGEALRAQGADITDDQTAELIKKYDSDSNGDIDTDE 298
Query: 142 FVQMM 146
F +++
Sbjct: 299 FRKLV 313
Score = 38.9 bits (89), Expect = 8e-04, Method: Compositional matrix adjust.
Identities = 28/105 (26%), Positives = 46/105 (43%)
Frame = +2
Query: 45 TEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAA 104
T+AE Q D DG+G+I E + + D ++++ E + +D D NG I
Sbjct: 119 TDAECQTAFAVFDTDGSGSISAGELGEALRAQGADI-TDDQTAELIKKYDSDSNGDIDTD 295
Query: 105 ELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK 149
E R ++ + + M + D DGDGQ+ E + K
Sbjct: 296 EFRKLVEGESDVARLAQSALMFKSLDADGDGQITASEITEAQGKK 430
>26019
Length = 1561
Score = 62.4 bits (150), Expect = 7e-11, Method: Compositional matrix adjust.
Identities = 37/111 (33%), Positives = 63/111 (56%), Gaps = 1/111 (0%)
Frame = +2
Query: 17 FSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARK 76
F D D G+++ E + + L QNP +Q +I+ D DGNG +DF EF+ +++
Sbjct: 116 FRKLDLDNSGSLSIDEFMS-LPELQQNPL---VQRVIDIFDTDGNGEVDFKEFIEGISQF 283
Query: 77 MKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNL-GEKLTDEEVDEMI 126
D E ++R AF+++D D +GYIS EL V+ + G L D ++ +++
Sbjct: 284 SVKGDKESKLRFAFKIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIV 436
Score = 29.3 bits (64), Expect = 0.70, Method: Compositional matrix adjust.
Identities = 18/61 (29%), Positives = 33/61 (54%)
Frame = +2
Query: 84 EEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFV 143
+ + + FR D D +G +S E +L E + V +I D DG+G+V+++EF+
Sbjct: 98 QRLGKRFRKLDLDNSGSLSIDEF----MSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFI 265
Query: 144 Q 144
+
Sbjct: 266 E 268
>01773
Length = 1950
Score = 58.9 bits (141), Expect = 8e-10, Method: Compositional matrix adjust.
Identities = 39/142 (27%), Positives = 71/142 (50%), Gaps = 7/142 (4%)
Frame = +1
Query: 13 FKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDAD-GNGTIDFPEF-- 69
+K+ F DK+ DG + KEL + + G + +++++ D D G+ I F F
Sbjct: 160 YKQLFKEADKNNDGYLEIKELRELFKRNGSSLSDSQIADTFVFFDGPRGDKRITFEXFCK 339
Query: 70 ----LTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEM 125
+ M +K+ E F+ DK G+GY+ EL+ ++ G+K T ++V +
Sbjct: 340 GLDQIVMFVQKLA---------ELFKAKDKSGDGYLDRDELKALLDESGQKFTADDVSAI 492
Query: 126 IREADIDGDGQVNYEEFVQMMT 147
++ AD + D ++ +EEFV T
Sbjct: 493 LKSADKNNDNKICFEEFVDACT 558
Score = 33.1 bits (74), Expect = 0.048, Method: Compositional matrix adjust.
Identities = 21/78 (26%), Positives = 40/78 (51%), Gaps = 2/78 (2%)
Frame = +1
Query: 71 TMMARKMKDT-DSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEV-DEMIRE 128
+ MA K K T + + ++ F+ DK+ +GY+ ELR + G L+D ++ D +
Sbjct: 112 SKMAAKGKGTGPNTDAYKQLFKEADKNNDGYLEIKELRELFKRNGSSLSDSQIADTFVFF 291
Query: 129 ADIDGDGQVNYEEFVQMM 146
GD ++ +E F + +
Sbjct: 292 DGPRGDKRITFEXFCKGL 345
>22273
Length = 297
Score = 55.8 bits (133), Expect = 6e-09, Method: Compositional matrix adjust.
Identities = 26/28 (92%), Positives = 27/28 (96%)
Frame = +1
Query: 122 VDEMIREADIDGDGQVNYEEFVQMMTAK 149
VDEMIREADIDGDGQVNYEEFV+MMT K
Sbjct: 1 VDEMIREADIDGDGQVNYEEFVKMMTTK 84
>04067
Length = 1920
Score = 51.2 bits (121), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 24/55 (43%), Positives = 37/55 (67%)
Frame = -1
Query: 19 LFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMM 73
+ DK G I ++L +++SLG + TE E++DMI E D DG+GT+D+ EF +M
Sbjct: 1920 VLDKGNKGVIPVEDLRWLLKSLGDDLTEDEIEDMILETDTDGSGTVDYEEFYKLM 1756
>07678
Length = 958
Score = 51.2 bits (121), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 42/143 (29%), Positives = 67/143 (46%), Gaps = 10/143 (6%)
Frame = +1
Query: 10 IAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAE-LQDMINEVDADGNGTIDFPE 68
I F + D DG+ ++ KE + G E + +Q+M D D +GTIDF E
Sbjct: 316 IKGLARKFKIMDDDGNRSLDFKEFKKGITEFGLTQFEGDVIQEMFTCFDKDZSGTIDFDE 495
Query: 69 FLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHV--MTNLGEKLTDEEVDEMI 126
FL + M ++ I+ AF+ DK G+G ++ +L+ V +T + L E +E I
Sbjct: 496 FLVKLRPPMSQM-RKDLIQRAFQKLDKTGDGVVTVEDLKGVYNVTKHPKYLNGEWTEERI 672
Query: 127 READIDG-------DGQVNYEEF 142
+D DG++ EEF
Sbjct: 673 LRIFLDSFDSPNDKDGKITKEEF 741
>15966
Length = 362
Score = 48.1 bits (113), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 30/100 (30%), Positives = 51/100 (51%), Gaps = 6/100 (6%)
Frame = +2
Query: 56 VDADGNGTIDFPEF------LTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHV 109
V + G+ I F EF + M +K+ E F+ DK G+GY+ EL+ +
Sbjct: 59 VPSCGDKRITFEEFCKGLDQIVMFVQKLA---------ELFKAKDKSGDGYLDRDELKAL 211
Query: 110 MTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK 149
+ G+K T ++V +++ AD + D ++ +EEFV T K
Sbjct: 212 LDESGQKFTADDVSAILKSADKNNDNKICFEEFVDACT*K 331
>17892
Length = 512
Score = 47.8 bits (112), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 21/60 (35%), Positives = 41/60 (68%), Gaps = 1/60 (1%)
Frame = +1
Query: 90 FRVFDKDGNGYISAAELRHVMTNLGEK-LTDEEVDEMIREADIDGDGQVNYEEFVQMMTA 148
F + DKD GY+S ++R + N G+ ++ E++ ++++E D + +GQV +E++QMM+A
Sbjct: 1 FELIDKDKKGYVSINDIRRALKNFGDGDVSGEQLHDILKEIDTNMNGQVELDEYLQMMSA 180
>04697
Length = 559
Score = 47.8 bits (112), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 21/69 (30%), Positives = 38/69 (55%)
Frame = +1
Query: 5 LTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTI 64
T+++I ++ + F D G +T +L + +G+ TE +L D+++EVD N +
Sbjct: 343 FTKDEINQYVKRFKSLDYQNKGFVTVNDLRRYFKKMGEKVTEDQLHDILSEVDLSRNAQV 522
Query: 65 DFPEFLTMM 73
D EFL +M
Sbjct: 523 DLGEFLQLM 549
>19912
Length = 865
Score = 44.3 bits (103), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 27/75 (36%), Positives = 39/75 (52%), Gaps = 1/75 (1%)
Frame = +2
Query: 70 LTMMARKMKDTDSEE-EIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIRE 128
L M + M DS + + F FDK+G I+ + R +T L +EVD ++ E
Sbjct: 623 LHPMVKLMAYIDSNNLRLVDFFNKFDKEGTMSITRDQFRQGLTEASIPLAGDEVDFLLDE 802
Query: 129 ADIDGDGQVNYEEFV 143
D DGDG++NY E V
Sbjct: 803 LDRDGDGEINYSELV 847
>07198
Length = 1675
Score = 44.3 bits (103), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 35/137 (25%), Positives = 68/137 (49%)
Frame = -3
Query: 8 EQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFP 67
E + E ++ F D + DG++ +KE + + + EL+ + + D + +GTI
Sbjct: 491 ELVDEDRKVFDAADANKDGSLNSKEYFAFF--MPNSFPQLELERFMRQSDKNKDGTISME 318
Query: 68 EFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIR 127
EF+ A T SE E+F+ +DKD +G +S E + ++ D EV+ +
Sbjct: 317 EFMPEGATGDTRTSSE----ESFKNYDKDKDGSLSLEEAMEWINPSSDEHADVEVEHLFT 150
Query: 128 EADIDGDGQVNYEEFVQ 144
D++ DG+++ +E +
Sbjct: 149 IGDVNHDGKLSKDEILN 99
>04643
Length = 1881
Score = 43.9 bits (102), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 18/52 (34%), Positives = 36/52 (69%), Gaps = 1/52 (1%)
Frame = +2
Query: 98 NGYISAAELR-HVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTA 148
+G + A E++ HV G+ +++E +D ++ ++D DG+G++NY+EF+ TA
Sbjct: 2 SGCLCADEIKAHVRALTGDDMSEEALDNLVSKSDADGNGKINYKEFLASWTA 157
Score = 37.4 bits (85), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 17/47 (36%), Positives = 30/47 (63%), Gaps = 1/47 (2%)
Frame = +2
Query: 26 GTITTKELGTVMRSL-GQNPTEAELQDMINEVDADGNGTIDFPEFLT 71
G + E+ +R+L G + +E L +++++ DADGNG I++ EFL
Sbjct: 5 GCLCADEIKAHVRALTGDDMSEEALDNLVSKSDADGNGKINYKEFLA 145
>26849
Length = 649
Score = 43.5 bits (101), Expect = 4e-05, Method: Compositional matrix adjust.
Identities = 23/65 (35%), Positives = 35/65 (53%)
Frame = +2
Query: 10 IAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEF 69
I AF + DKDG ++ +E + + + EA+++DM D DGNGTI+ EF
Sbjct: 164 ILGLARAFRVMDKDGSKVLSLEEFKKGILDMHIDINEADIEDMFYRFDNDGNGTINMTEF 343
Query: 70 LTMMA 74
L +A
Sbjct: 344 LLKVA 358
Score = 38.1 bits (87), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 18/58 (31%), Positives = 34/58 (58%)
Frame = +2
Query: 86 IREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFV 143
+ AFRV DKDG+ +S E + + ++ + + ++++M D DG+G +N EF+
Sbjct: 173 LARAFRVMDKDGSKVLSLEEFKKGILDMHIDINEADIEDMFYRFDNDGNGTINMTEFL 346
>00167
Length = 2176
Score = 43.1 bits (100), Expect = 4e-05, Method: Compositional matrix adjust.
Identities = 24/62 (38%), Positives = 36/62 (58%)
Frame = +3
Query: 45 TEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAA 104
T EL ++ D DG GT+DF EFL + KM + + +++AF DK G+G I+A
Sbjct: 834 TSEELNEVFRRFDKDGTGTLDFEEFLLALRPKMNEF-RRKLVKKAFAKMDKTGDGIITAD 1010
Query: 105 EL 106
+L
Sbjct: 1011DL 1016
>32088
Length = 1928
Score = 43.1 bits (100), Expect = 5e-05, Method: Composition-based stats.
Identities = 22/64 (34%), Positives = 33/64 (51%)
Frame = +1
Query: 79 DTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVN 138
D D E+R F D D NG+IS EL +G + E+ ++ + D GDG++N
Sbjct: 928 DEDQLTELRSVFDSIDDDNNGHISXGELDSAFRAVGLNIPGYELRTIMSKYDASGDGRLN 1107
Query: 139 YEEF 142
+EF
Sbjct: 1108MDEF 1119
>05230
Length = 843
Score = 38.5 bits (88), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 35/124 (28%), Positives = 63/124 (50%), Gaps = 3/124 (2%)
Frame = -2
Query: 25 DGTITTKELGTVMRSLG-QNPTEAE--LQDMINEVDADGNGTIDFPEFLTMMARKMKDTD 81
DG + E +M LG N EA L D +V+ D + E++++M+ D
Sbjct: 815 DGRLNLFEFTRLMTLLGLPNAQEAAKVLFDKQTKVERD---RLRMEEYISIMSDASVDMK 645
Query: 82 SEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEE 141
+ R+ F FD DG+G+ S ++ + N+G +T ++ I+ D + DG++NY +
Sbjct: 644 TNM-WRKLFAQFDTDGSGWASREDVIEGLENIGITIT-PDLRAKIKAMDGNKDGKINYAD 471
Query: 142 FVQM 145
F++M
Sbjct: 470 FLRM 459
>13028
Length = 1273
Score = 38.5 bits (88), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 31/110 (28%), Positives = 51/110 (46%), Gaps = 10/110 (9%)
Frame = -1
Query: 27 TITTKELGTVMRSLGQNPTEAELQDMINEVDAD-----GNGT--IDFPEFLTMMARKMKD 79
TI E+ VMR+LG PTE E++DM+NEV G +D F+ +
Sbjct: 1063 TIPLSEVPFVMRALGFYPTEQEIEDMLNEVKFSRYVETGQYVEELDLGTFIKLYVNHRPA 884
Query: 80 TD-SEEEIREAFRVF--DKDGNGYISAAELRHVMTNLGEKLTDEEVDEMI 126
S ++++ AF G + EL ++ + GE +T+ E+ E +
Sbjct: 883 FGLSPDKLQWAFDTLGMPSPAGGAVDRGELLDILQSKGEHMTEYELAEYL 734
>17977
Length = 445
Score = 38.1 bits (87), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 22/82 (26%), Positives = 40/82 (48%), Gaps = 2/82 (2%)
Frame = +3
Query: 70 LTMMARKMK--DTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIR 127
+ M +++K + S ++ AFR +DKDG G I +LR + ++++
Sbjct: 171 VAAMRQQLKKFNYHSFPDLIRAFRFYDKDGKGKIDIDDLREACRKFDVPIDVWLLEQVFD 350
Query: 128 EADIDGDGQVNYEEFVQMMTAK 149
D + DGQ++Y EF + K
Sbjct: 351 YCDENRDGQIDYLEFANFLNWK 416
>03616
Length = 2372
Score = 36.2 bits (82), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 18/68 (26%), Positives = 39/68 (57%)
Frame = +2
Query: 75 RKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGD 134
+K+ TD + + E F +D+D GYIS +R + L + D+ + ++++ +D +
Sbjct: 857 KKIAITD-KSRVDEMFLRYDRDRTGYISVENMRDLCRRLQLPVDDDVILALVQQCTMDQE 1033
Query: 135 GQVNYEEF 142
G+++ E+F
Sbjct: 1034GRISLEDF 1057
>08380
Length = 1236
Score = 35.4 bits (80), Expect = 0.010, Method: Compositional matrix adjust.
Identities = 43/160 (26%), Positives = 72/160 (45%), Gaps = 28/160 (17%)
Frame = -1
Query: 11 AEFKEAFSLFDKDGDGTITTKEL-GTVMRSLGQNPTEA--ELQDMINEVDADGNGTIDFP 67
++ K+ D D DG ++ EL V + ++ +EA E +++ +D D NG + +
Sbjct: 885 SKLKDIVYKVDSDKDGKLSVAELEAWVKDKMEEHFSEATQENEEIFKHLDPDNNGKVHWK 706
Query: 68 EFLT--MMARKMK----------------DTDSEEEI-REAFRVFDKDG---NGYISAAE 105
E+ ++A+ K D D++EEI R FR D DG + ++ E
Sbjct: 705 EYYVHFLLAKGYKQDVASRHVVDYDZIQLDPDAKEEIIRYKFRWSDADGEPMDNELTREE 526
Query: 106 L---RHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEF 142
RH EK + V+ ++ D +GDG V EEF
Sbjct: 525 FMSFRH--PEQSEKTLNNMVNGILGGIDTNGDGVVTEEEF 412
>18677
Length = 754
Score = 34.7 bits (78), Expect = 0.014, Method: Compositional matrix adjust.
Identities = 22/74 (29%), Positives = 35/74 (47%)
Frame = +2
Query: 2 ADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGN 61
A +L +E I ++E F FDK+ G + T ELG + LG T L ++ D
Sbjct: 482 AKRLWKE-IKAYREVFLQFDKNRSGLVDTYELGNMFSKLGFPVTRPVLTSIVRRY-GDRR 655
Query: 62 GTIDFPEFLTMMAR 75
I +F+ ++ R
Sbjct: 656 NQISLEDFVVVILR 697
>35350
Length = 339
Score = 33.5 bits (75), Expect = 0.036, Method: Compositional matrix adjust.
Identities = 20/45 (44%), Positives = 25/45 (55%)
Frame = +2
Query: 32 ELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARK 76
EL +M LG T L+ MI EVD D + I F EFL ++ RK
Sbjct: 11 ELKYMMEKLGAPQTHLGLKKMIAEVDEDHDSKISFREFL-LIYRK 142
>28617
Length = 348
Score = 33.1 bits (74), Expect = 0.048, Method: Compositional matrix adjust.
Identities = 12/23 (52%), Positives = 20/23 (86%)
Frame = -2
Query: 124 EMIREADIDGDGQVNYEEFVQMM 146
EM+ EAD++GDGQ++ EF+++M
Sbjct: 338 EMVEEADVNGDGQIDQSEFIRIM 270
Score = 26.2 bits (56), Expect = 5.5, Method: Compositional matrix adjust.
Identities = 10/25 (40%), Positives = 17/25 (68%)
Frame = -2
Query: 49 LQDMINEVDADGNGTIDFPEFLTMM 73
++M+ E D +G+G ID EF+ +M
Sbjct: 344 WREMVEEADVNGDGQIDQSEFIRIM 270
>22490
Length = 743
Score = 31.6 bits (70), Expect = 0.15, Method: Compositional matrix adjust.
Identities = 13/23 (56%), Positives = 19/23 (82%)
Frame = -1
Query: 122 VDEMIREADIDGDGQVNYEEFVQ 144
VDE++RE D+D DG V+Y EF++
Sbjct: 467 VDEILREDDLDKDGYVDYTEFMK 399
>28023
Length = 475
Score = 30.8 bits (68), Expect = 0.22, Method: Compositional matrix adjust.
Identities = 14/30 (46%), Positives = 21/30 (70%)
Frame = -1
Query: 118 TDEEVDEMIREADIDGDGQVNYEEFVQMMT 147
TD+EVDE+I D + DG+V++ EF + M
Sbjct: 475 TDQEVDEVIDYIDKNKDGKVDFSEFYKFMV 386
>01130
Length = 1032
Score = 30.4 bits (67), Expect = 0.28, Method: Compositional matrix adjust.
Identities = 15/54 (27%), Positives = 28/54 (51%)
Frame = +3
Query: 90 FRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFV 143
FR D G G++ RHV +LT + + ++ +D+ DG+++ +EF
Sbjct: 549 FRALDVQGKGFLDGDCCRHVFE--ASELTSDVLSDVWNLSDVTRDGKLDVDEFC 704
>15239
Length = 913
Score = 28.5 bits (62), Expect = 1.2, Method: Compositional matrix adjust.
Identities = 17/58 (29%), Positives = 33/58 (56%), Gaps = 1/58 (1%)
Frame = +2
Query: 87 REAFRVF-DKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFV 143
R+ F+ F DK+ +G + A E+R + + E +I ++D D DG+++Y+E +
Sbjct: 20 RDQFQQFRDKNNDGKLDANEVREWIIPDDYDHSSAEAKHLIGDSDGDKDGKLSYDEIL 193
>30885
Length = 1090
Score = 28.1 bits (61), Expect = 1.4, Method: Compositional matrix adjust.
Identities = 16/59 (27%), Positives = 30/59 (50%)
Frame = -1
Query: 86 IREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQ 144
++ F+ FD+ NG+I+ + +T L ++ E+ + EA D VNY F++
Sbjct: 793 LKPVFQDFDRHNNGHITRVQFSQGLTMLEIPISTPELAAL--EARFYNDVGVNYLAFLK 623
>12671
Length = 807
Score = 27.7 bits (60), Expect = 2.0, Method: Compositional matrix adjust.
Identities = 14/60 (23%), Positives = 30/60 (50%)
Frame = -2
Query: 90 FRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK 149
+R DKDG G + +L + L E ++++ D DG+ +++Y F++ + +
Sbjct: 797 YRQLDKDGTGILLQHDLERGLLRFHVDLPPEVLEQVFEIVDPDGERRLDYSFFMRTVLGQ 618
>13551
Length = 529
Score = 27.3 bits (59), Expect = 2.2, Method: Compositional matrix adjust.
Identities = 12/37 (32%), Positives = 23/37 (62%)
Frame = +1
Query: 113 LGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK 149
+GE + + +V + +RE D + DG +++EEF + K
Sbjct: 55 MGEIVNEVKVTQWLREEDKNVDGCLDFEEFCALYKKK 165
>05818
Length = 1203
Score = 26.6 bits (57), Expect = 3.8, Method: Compositional matrix adjust.
Identities = 14/36 (38%), Positives = 18/36 (50%)
Frame = +1
Query: 41 GQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARK 76
G PT Q ++NEV+A D FLT+M K
Sbjct: 712 GMIPTR---QKLVNEVEASARSLTDCRTFLTIMGLK 810
>33397
Length = 1723
Score = 26.2 bits (56), Expect = 5.2, Method: Compositional matrix adjust.
Identities = 18/52 (34%), Positives = 30/52 (57%), Gaps = 1/52 (1%)
Frame = +3
Query: 92 VFDKDG-NGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEF 142
+F K G +G IS ++ ++T L + E+ R DI+GDG+++ EEF
Sbjct: 111 IFYKLGEHGLISFSDYIFLLTVLSTPPRNFEI--AFRMFDINGDGELDLEEF 260
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000308783 | hsapiens_gene_ensembl | X-linked
retinitis pigmentosa GTPase regulator.
[Source:Uniprot/SWISSPROT;Acc:Q92834]
(753 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
02938 272 4e-73
26574 56 6e-08
20162 53 5e-07
12101 49 8e-06
03352 42 0.001
01451 39 0.006
39525 35 0.100
>02938
Length = 1718
Score = 272 bits (695), Expect = 4e-73, Method: Compositional matrix adjust.
Identities = 141/300 (47%), Positives = 195/300 (65%), Gaps = 2/300 (0%)
Frame = +3
Query: 55 KLYMFGSNNWGQLGLGSKSAISKPTCVKALKPEKVKLAACGRNHTLVSTEGGNVYATGGN 114
+++MFG N++GQLG+G++ ++P+CVK+LK EK +L ACGR+HT+V+TE GN+YA G N
Sbjct: 18 RVFMFGPNDYGQLGIGAQKVANRPSCVKSLKHEKARLVACGRSHTIVATESGNIYAFGAN 197
Query: 115 NEGQLGL-GDTEERNTFHVISFFTSEHKIKQLSAGSNTSAALTEDGRLFMWGDNSEGQIG 173
EGQLG+ G TE V S + K+ L+AG + S ALTEDGR+F+WG N EGQ+G
Sbjct: 198 GEGQLGVEGVTETNLPKQVDSLQATPWKM--LAAGCDHSLALTEDGRVFVWGGNGEGQLG 371
Query: 174 LKNVSNVCVPQQVTIGKPVSWISCGYYHSAFVTTDGELYVFGEPENGKLGLPNQLLGNHR 233
+ S++ VP+Q+ +G+ V+ I+ GYYHSA VT GELY FGE + GKLGL N +
Sbjct: 372 MGEDSDIPVPRQLDVGQSVACIASGYYHSALVTESGELYTFGESDGGKLGL-NGDTDECK 548
Query: 234 TPQLVSEIPEKVIQVACGGEHTVVLTENA-VYXXXXXXXXXXXXXXXXXETSEPKVIENI 292
TPQ V I +KV V+CGG HTV LTE VY E+ P +++
Sbjct: 549 TPQQVMAINDKVKSVSCGGSHTVALTEKGEVYAFGEGSSGQLGLGVSTLESESPSLLK-- 722
Query: 293 RDQTISYISCGENHTALITDIGLMYTFGDGRHGKLGLGLENFTNHFIPTLCSNFLRFIVK 352
++ + CGEN T ++++ G +YTFGDGRHGKL LG E+F+N F+ T FL+F VK
Sbjct: 723 LPFKVAQVCCGENFTTVVSERGQLYTFGDGRHGKLALGQESFSNQFVCTKVDRFLKFNVK 902
Score = 66.6 bits (161), Expect = 3e-11, Method: Compositional matrix adjust.
Identities = 47/135 (34%), Positives = 66/135 (48%), Gaps = 11/135 (8%)
Frame = +3
Query: 7 LMPDSGAVFTFGKS---KFAENN-------PGKFWFKNDVPVHLSCGDEHSAVVTGNNKL 56
L+ +SG ++TFG+S K N P + ND +SCG H+ +T ++
Sbjct: 462 LVTESGELYTFGESDGGKLGLNGDTDECKTPQQVMAINDKVKSVSCGGSHTVALTEKGEV 641
Query: 57 YMFGSNNWGQLGLGSKSAISK-PTCVKALKPEKVKLAACGRNHTLVSTEGGNVYATGGNN 115
Y FG + GQLGLG + S+ P+ +K P KV CG N T V +E G +Y G
Sbjct: 642 YAFGEGSSGQLGLGVSTLESESPSLLKL--PFKVAQVCCGENFTTVVSERGQLYTFGDGR 815
Query: 116 EGQLGLGDTEERNTF 130
G+L LG N F
Sbjct: 816 HGKLALGQESFSNQF 860
Score = 47.0 bits (110), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 41/154 (26%), Positives = 71/154 (46%), Gaps = 15/154 (9%)
Frame = +3
Query: 8 MPDSGAVFTFGKSKFAENNPGKFWFKNDVP---------VHLSCGDEHSAVVTGNNKLYM 58
+ + G V+ FG+ + G +++ P + CG+ + VV+ +LY
Sbjct: 621 LTEKGEVYAFGEGSSGQLGLGVSTLESESPSLLKLPFKVAQVCCGENFTTVVSERGQLYT 800
Query: 59 FGSNNWGQLGLGSKSAISKPTCVKALKPEK--VKLAACGRNHTLVST----EGGNVYATG 112
FG G+L LG +S ++ C K + K VK AACG H +V E G+V A+
Sbjct: 801 FGDGRHGKLALGQESFSNQFVCTKVDRFLKFNVKKAACGGCHLIVMASPKLENGDV-ASE 977
Query: 113 GNNEGQLGLGDTEERNTFHVISFFTSEHKIKQLS 146
EGQ+ + T R++ + F++ + + S
Sbjct: 978 DEEEGQIMMNGT-IRDSLSLTRTFSARDRRRNAS 1076
>26574
Length = 441
Score = 55.8 bits (133), Expect = 6e-08, Method: Composition-based stats.
Identities = 32/96 (33%), Positives = 52/96 (54%)
Frame = +3
Query: 59 FGSNNWGQLGLGSKSAISKPTCVKALKPEKVKLAACGRNHTLVSTEGGNVYATGGNNEGQ 118
+G ++ +LG G+ + +P V AL+ +KV ACG H + T+ G V+ G N+EGQ
Sbjct: 6 WGKGDYHRLGHGTDDHVRRPRRVSALQGKKVIDVACGSLHCVACTDSGEVFTWGDNDEGQ 185
Query: 119 LGLGDTEERNTFHVISFFTSEHKIKQLSAGSNTSAA 154
LG G T +++ + KI +++ GS S A
Sbjct: 186 LGDGTTNAIQRPRMVAALQGK-KINRVACGSAHSLA 290
Score = 54.7 bits (130), Expect = 1e-07, Method: Composition-based stats.
Identities = 23/63 (36%), Positives = 39/63 (61%)
Frame = +3
Query: 38 VHLSCGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKSAISKPTCVKALKPEKVKLAACGRN 97
+ ++CG H T + +++ +G N+ GQLG G+ +AI +P V AL+ +K+ ACG
Sbjct: 99 IDVACGSLHCVACTDSGEVFTWGDNDEGQLGDGTTNAIQRPRMVAALQGKKINRVACGSA 278
Query: 98 HTL 100
H+L
Sbjct: 279 HSL 287
Score = 48.1 bits (113), Expect = 1e-05, Method: Composition-based stats.
Identities = 23/64 (35%), Positives = 36/64 (56%), Gaps = 2/64 (3%)
Frame = +3
Query: 141 KIKQLSAGSNTSAALTEDGRLFMWGDNSEGQIGLKNVSNVCVPQQVTI--GKPVSWISCG 198
K+ ++ GS A T+ G +F WGDN EGQ+G + + P+ V GK ++ ++CG
Sbjct: 93 KVIDVACGSLHCVACTDSGEVFTWGDNDEGQLGDGTTNAIQRPRMVAALQGKKINRVACG 272
Query: 199 YYHS 202
HS
Sbjct: 273 SAHS 284
Score = 36.2 bits (82), Expect = 0.047, Method: Composition-based stats.
Identities = 15/48 (31%), Positives = 27/48 (56%)
Frame = +3
Query: 286 PKVIENIRDQTISYISCGENHTALITDIGLMYTFGDGRHGKLGLGLEN 333
P+ + ++ + + ++CG H TD G ++T+GD G+LG G N
Sbjct: 63 PRRVSALQGKKVIDVACGSLHCVACTDSGEVFTWGDNDEGQLGDGTTN 206
Score = 34.7 bits (78), Expect = 0.15, Method: Composition-based stats.
Identities = 19/76 (25%), Positives = 34/76 (44%), Gaps = 1/76 (1%)
Frame = +3
Query: 233 RTPQLVSEIP-EKVIQVACGGEHTVVLTENAVYXXXXXXXXXXXXXXXXXETSEPKVIEN 291
R P+ VS + +KVI VACG H V T++ P+++
Sbjct: 57 RRPRRVSALQGKKVIDVACGSLHCVACTDSGEVFTWGDNDEGQLGDGTTNAIQRPRMVAA 236
Query: 292 IRDQTISYISCGENHT 307
++ + I+ ++CG H+
Sbjct: 237 LQGKKINRVACGSAHS 284
>20162
Length = 1121
Score = 52.8 bits (125), Expect = 5e-07, Method: Compositional matrix adjust.
Identities = 62/246 (25%), Positives = 95/246 (38%), Gaps = 30/246 (12%)
Frame = +1
Query: 45 EHSAVVTGNNKLYMFGSNNWGQLGL---GSKSAISKPTCVKA-LKPEKVKL--------- 91
E S + N LY FG +GQLG G S K + P KV +
Sbjct: 109 EFSTMSDINGNLYSFGCPEYGQLGHNSDGKYFVTSNKMEYKCEMTPRKVSVFIEKTRDGH 288
Query: 92 -----------AACGRNHTLVSTEGGNVYATGGNNEGQLGLGDTEERNTFHVISFFTSEH 140
ACG NHTL+ +++ G G+LG + ++ +I FF
Sbjct: 289 VMPITDVDIREVACGLNHTLIMDSKKRLFSWGFGGYGRLGHAEPKDELVPRLIKFFDGPG 468
Query: 141 K-IKQLSAGSNTSAALTEDGRLFMWGDN---SEGQIGLKNVSNVCVPQQVTIGKPVSWIS 196
+ Q+ GS+ + E G L+ WG + E + K V ++ G V I
Sbjct: 469 RGGSQIQCGSSFCMTVNEHGALYFWGQSKPTGEATMYPKLVQDLS-------GWKVRSIG 627
Query: 197 CGYYHSAFVTTDGELYVFG-EPENGKLGLPNQLLGNHRTPQLVSEIPEKVIQ-VACGGEH 254
C Y S + D + +G P G+LG + + Q V + + VACG H
Sbjct: 628 C-CYRSIVLCADDSVVSWGPSPTYGELGYGENKMKSSTVAQEVKPLDGVYVHDVACGYAH 804
Query: 255 TVVLTE 260
T+++
Sbjct: 805 TLMIAR 822
Score = 31.2 bits (69), Expect = 1.6, Method: Compositional matrix adjust.
Identities = 13/37 (35%), Positives = 23/37 (62%)
Frame = +1
Query: 292 IRDQTISYISCGENHTALITDIGLMYTFGDGRHGKLG 328
I D I ++CG NHT ++ ++++G G +G+LG
Sbjct: 298 ITDVDIREVACGLNHTLIMDSKKRLFSWGFGGYGRLG 408
>12101
Length = 1020
Score = 48.9 bits (115), Expect = 8e-06, Method: Compositional matrix adjust.
Identities = 46/160 (28%), Positives = 69/160 (43%), Gaps = 9/160 (5%)
Frame = -2
Query: 56 LYMFGSNNWGQLGLGSKSAISKPTCVKALKPEK-----VKLAACGRNHTLVSTEGGNVYA 110
++ G NN+ QL ++ + L P K VK A G++HTL+ A
Sbjct: 860 IWAVGLNNYKQLAHPKETE-------RFLTPVKTEIKDVKQIAGGQHHTLILDNNMRCLA 702
Query: 111 TGGNNEGQLGLGDTEERNTFHVISFFTSEHKIKQLSAGSNTSAALTEDGRLFMWGDNSEG 170
G G+LGLG E T + K+ ++ G S +T DG+L+ WG S
Sbjct: 701 VGRPEYGRLGLGKVTEVVT-KPTAITQLNGKVNYVACGEACSFXITNDGKLYSWGMGSLL 525
Query: 171 QIGLKNVSNVCVPQQV----TIGKPVSWISCGYYHSAFVT 206
Q+G+ + + VP +V T K V G HS F+
Sbjct: 524 QLGVGDGDDEVVPVEVSSKNTQNKKVLLADGGGQHSVFLV 405
Score = 48.1 bits (113), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 46/161 (28%), Positives = 75/161 (46%), Gaps = 5/161 (3%)
Frame = -2
Query: 108 VYATGGNNEGQLGLGDTEERNTFHVISFFTSEHKIKQLSAGSNTSAALTEDGRLFMWGDN 167
++A G NN QL ER + T +KQ++ G + + L + R G
Sbjct: 860 IWAVGLNNYKQLAHPKETER---FLTPVKTEIKDVKQIAGGQHHTLILDNNMRCLAVGRP 690
Query: 168 SEGQIGLKNVSNVCV-PQQVT-IGKPVSWISCGYYHSAFVTTDGELYVFGEPENGKLGLP 225
G++GL V+ V P +T + V++++CG S +T DG+LY +G +LG+
Sbjct: 689 EYGRLGLGKVTEVVTKPTAITQLNGKVNYVACGEACSFXITNDGKLYSWGMGSLLQLGVG 510
Query: 226 NQLLGNHRTPQLVSEI---PEKVIQVACGGEHTVVLTENAV 263
+ + P VS +KV+ GG+H+V L E V
Sbjct: 509 DG--DDEVVPVEVSSKNTQNKKVLLADGGGQHSVFLVEADV 393
Score = 36.2 bits (82), Expect = 0.051, Method: Compositional matrix adjust.
Identities = 24/87 (27%), Positives = 42/87 (48%), Gaps = 1/87 (1%)
Frame = -2
Query: 245 VIQVACGGEHTVVLTENAVYXXXXXXXXXXXXXXXXXET-SEPKVIENIRDQTISYISCG 303
V Q+A G HT++L N E ++P I + + ++Y++CG
Sbjct: 767 VKQIAGGQHHTLILDNNMRCLAVGRPEYGRLGLGKVTEVVTKPTAITQLNGK-VNYVACG 591
Query: 304 ENHTALITDIGLMYTFGDGRHGKLGLG 330
E + IT+ G +Y++G G +LG+G
Sbjct: 590 EACSFXITNDGKLYSWGMGSLLQLGVG 510
Score = 32.7 bits (73), Expect = 0.57, Method: Compositional matrix adjust.
Identities = 22/68 (32%), Positives = 35/68 (51%), Gaps = 2/68 (2%)
Frame = -2
Query: 39 HLSCGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKSAISKPTCV--KALKPEKVKLAACGR 96
+++CG+ S +T + KLY +G + QLG+G P V K + +KV LA G
Sbjct: 605 YVACGEACSFXITNDGKLYSWGMGSLLQLGVGDGDDEVVPVEVSSKNTQNKKVLLADGGG 426
Query: 97 NHTLVSTE 104
H++ E
Sbjct: 425 QHSVFLVE 402
>03352
Length = 935
Score = 41.6 bits (96), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 37/130 (28%), Positives = 55/130 (42%), Gaps = 16/130 (12%)
Frame = +2
Query: 7 LMPDSGAVFTFGKSKFAENN---------------PGKFW-FKNDVPVHLSCGDEHSAVV 50
++ D G+VF G +K E+ P K +N V ++C SAVV
Sbjct: 80 MLADDGSVFFVGLAKRGEDGDSGAAKGRRQPKSVKPKKMIRVENKQVVFVACNSGSSAVV 259
Query: 51 TGNNKLYMFGSNNWGQLGLGSKSAISKPTCVKALKPEKVKLAACGRNHTLVSTEGGNVYA 110
T + ++YMFG + + V LK V A G+ HT+ T G ++
Sbjct: 260 TKDGEVYMFGKD--------TSHCDHASGHVTDLKDVVVTQVALGKAHTVALTSKGQLFT 415
Query: 111 TGGNNEGQLG 120
G NN+GQ G
Sbjct: 416 FGINNKGQCG 445
Score = 41.2 bits (95), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 38/134 (28%), Positives = 60/134 (44%), Gaps = 10/134 (7%)
Frame = +2
Query: 136 FTSEHKIKQLSAGSNTSAAL--TEDGRLFMWGDNSEGQ-------IGLKNVSNVCVPQQV 186
T KI+Q++ G + AL +DG +F G G+ G + +V + +
Sbjct: 20 ITKSPKIQQVATGHEGAHALMLADDGSVFFVGLAKRGEDGDSGAAKGRRQPKSVKPKKMI 199
Query: 187 TI-GKPVSWISCGYYHSAFVTTDGELYVFGEPENGKLGLPNQLLGNHRTPQLVSEIPEKV 245
+ K V +++C SA VT DGE+Y+FG+ + +H + + V
Sbjct: 200 RVENKQVVFVACNSGSSAVVTKDGEVYMFGK---------DTSHCDHASGHVTDLKDVVV 352
Query: 246 IQVACGGEHTVVLT 259
QVA G HTV LT
Sbjct: 353 TQVALGKAHTVALT 394
Score = 36.2 bits (82), Expect = 0.050, Method: Compositional matrix adjust.
Identities = 32/137 (23%), Positives = 56/137 (40%), Gaps = 9/137 (6%)
Frame = +2
Query: 201 HSAFVTTDGELYVFGEPENGKLGLPNQLLGNHRTPQLVSEIPEKVIQV--------AC-G 251
H+ + DG ++ G + G+ G G R P+ V P+K+I+V AC
Sbjct: 71 HALMLADDGSVFFVGLAKRGEDGDSGAAKG-RRQPKSVK--PKKMIRVENKQVVFVACNS 241
Query: 252 GEHTVVLTENAVYXXXXXXXXXXXXXXXXXETSEPKVIENIRDQTISYISCGENHTALIT 311
G VV + VY + +++D ++ ++ G+ HT +T
Sbjct: 242 GSSAVVTKDGEVYMFGKDTSHCDHASGH---------VTDLKDVVVTQVALGKAHTVALT 394
Query: 312 DIGLMYTFGDGRHGKLG 328
G ++TFG G+ G
Sbjct: 395 SKGQLFTFGINNKGQCG 445
>01451
Length = 1229
Score = 39.3 bits (90), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 18/49 (36%), Positives = 27/49 (55%)
Frame = -3
Query: 289 IENIRDQTISYISCGENHTALITDIGLMYTFGDGRHGKLGLGLENFTNH 337
IE + D + I+ G +H A +TD+G +YT G G+LG E F+
Sbjct: 1179 IEVLPDAVVVKIASGSDHIACLTDLGELYTLGCAEQGQLGRVAECFSTR 1033
>39525
Length = 450
Score = 35.0 bits (79), Expect = 0.100, Method: Composition-based stats.
Identities = 13/38 (34%), Positives = 27/38 (71%), Gaps = 2/38 (5%)
Frame = -3
Query: 141 KIKQLSAGSNTS--AALTEDGRLFMWGDNSEGQIGLKN 176
K++ +++G N A+T++G+++ WG N +GQ+GL +
Sbjct: 163 KVRTIASGCNACHCVAITDEGKVYTWGRNEKGQLGLSD 50
Score = 30.8 bits (68), Expect = 2.0, Method: Composition-based stats.
Identities = 17/41 (41%), Positives = 24/41 (58%)
Frame = -3
Query: 289 IENIRDQTISYISCGENHTALITDIGLMYTFGDGRHGKLGL 329
+E I+ +TI+ C H ITD G +YT+G G+LGL
Sbjct: 175 LEGIKVRTIAS-GCNACHCVAITDEGKVYTWGRNEKGQLGL 56
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000274026 | hsapiens_gene_ensembl | Cyclin-A2
(Cyclin-A). [Source:Uniprot/SWISSPROT;Acc:P20248]
(432 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
11451 270 1e-72
16444 194 5e-50
25961 134 1e-31
38040 33 0.21
04744 29 2.8
>11451
Length = 1321
Score = 270 bits (689), Expect = 1e-72, Method: Compositional matrix adjust.
Identities = 136/252 (53%), Positives = 180/252 (71%), Gaps = 1/252 (0%)
Frame = +2
Query: 172 VNEVPDYHEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEEYKLQNET 231
+ EVP+Y EDI++YL +E K +P+ G+MK+Q D+T +MRAILVDWLVEV EEYKLQ ET
Sbjct: 476 IEEVPEYAEDIYSYLLSVEHKNRPRPGFMKRQEDVTMAMRAILVDWLVEVAEEYKLQRET 655
Query: 232 LHLAVNYIDRFLSSMSVLRGKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQV 291
L L V +IDRFL+ MSVLR KLQLVG AAM LA+K+EEIYPP+V EFVYITDDT KKQ+
Sbjct: 656 LFLTVTFIDRFLAHMSVLRSKLQLVGAAAMFLAAKYEEIYPPDVNEFVYITDDTXQKKQI 835
Query: 292 LRMEHLVLKVLTFDLAAPTVNQFLTQYFLHQQPANCKVESLAMFLGELSLIDADPYLKYL 351
LRMEHL+LKVL FD++ PTVN F ++ L + A +++L M+L EL L++ + YL +
Sbjct: 836 LRMEHLILKVLKFDISTPTVNWF-SERLLRKVKAEDSLKNLTMYLCELVLVEYEKYLVFP 1012
Query: 352 PSVIAGAAFHLALYTVTGQS-WPESLIRKTGYTLESLKPCLMDLHQTYLKAPQHAQQSIR 410
S++A +A LA YT+ Q W R + Y+L L PC+ L+ + H QQ++R
Sbjct: 1013NSLVAASALCLANYTLHQQHFWSAEHERVSSYSLSQLLPCVQMLYDMHCHIEHHPQQAVR 1192
Query: 411 EKYKNSKYHGVS 422
EKY+ SKY V+
Sbjct: 1193EKYRLSKYDSVA 1228
>16444
Length = 2113
Score = 194 bits (493), Expect = 5e-50, Method: Compositional matrix adjust.
Identities = 103/241 (42%), Positives = 152/241 (63%), Gaps = 2/241 (0%)
Frame = -2
Query: 194 KPKVGYMKKQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLRGKL 253
+P+ G+M QP++T +MR ILVDWLVE+G+E+++ +E L LAV +DR+L+ + V R L
Sbjct: 1260 RPQQGFMGHQPELTLTMRTILVDWLVELGDEFEVCHEGLFLAVKILDRYLAQVKVNRCNL 1081
Query: 254 QLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLKVLTFDLAAPTVNQ 313
QLVG AA LASK+EEIYPP V + Y+TDDT T +QVLRME + L DL P++
Sbjct: 1080 QLVGAAAFFLASKYEEIYPPCVEDIAYMTDDTCTARQVLRMERRIFVKLDHDLNGPSIGW 901
Query: 314 FLTQYF-LHQQPANCKVESLAMFLGELSLIDADPYLKYLPSVIAGAAFHLALYTVTGQS- 371
F + + P N +E L MFL L+ + D +L+Y PS+IA +AF LA YT+ ++
Sbjct: 900 FAQRLCKVTGSPEN--LEQLTMFLCYLAXLHIDXFLEYPPSIIAASAFCLARYTLRDRTP 727
Query: 372 WPESLIRKTGYTLESLKPCLMDLHQTYLKAPQHAQQSIREKYKNSKYHGVSLLNPPETLN 431
W + K+ Y L L C+ +L+ YL++ Q QQ+ + K+ ++ VS + PP+ L
Sbjct: 726 WDRLCVMKSQYYLHELLSCIDELYAAYLESFQSQQQACQNKFGKERFGMVSRIPPPQQLI 547
Query: 432 L 432
L
Sbjct: 546 L 544
>25961
Length = 538
Score = 134 bits (336), Expect = 1e-31, Method: Compositional matrix adjust.
Identities = 66/145 (45%), Positives = 92/145 (63%)
Frame = -1
Query: 175 VPDYHEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEEYKLQNETLHL 234
V +Y DI+ Y+R+ME + + Y++ DIT MR ILVDWL +V + L ETL+L
Sbjct: 520 VSEYVNDIYDYMRQMEQRLCVRASYLEG-TDITGKMRCILVDWLCQVHHRFHLLQETLYL 344
Query: 235 AVNYIDRFLSSMSVLRGKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRM 294
V+ +DRFL V R KLQLVG +ML+ASK+EE++ PEVA+FVYI+D+ Y K + M
Sbjct: 343 TVSIMDRFLQQKPVTRNKLQLVGVTSMLVASKYEELFAPEVADFVYISDNAYAKADIHEM 164
Query: 295 EHLVLKVLTFDLAAPTVNQFLTQYF 319
E +L+ L F P V+ F + F
Sbjct: 163 ERDILRTLNFSFGKPFVSTFSEEEF 89
>38040
Length = 374
Score = 33.1 bits (74), Expect = 0.21, Method: Compositional matrix adjust.
Identities = 16/56 (28%), Positives = 30/56 (53%)
Frame = +2
Query: 371 SWPESLIRKTGYTLESLKPCLMDLHQTYLKAPQHAQQSIREKYKNSKYHGVSLLNP 426
W +L TGY L+ LKP +++L+ ++R+KY++ +H V+ + P
Sbjct: 11 GWTPTLHFYTGYRLKELKPLILELNTMLCSKRYPDLVTVRDKYRHHLFHSVAEIAP 178
>04744
Length = 1778
Score = 29.3 bits (64), Expect = 2.8, Method: Compositional matrix adjust.
Identities = 13/37 (35%), Positives = 22/37 (59%)
Frame = -1
Query: 284 DTYTKKQVLRMEHLVLKVLTFDLAAPTVNQFLTQYFL 320
DT+T +V+ V ++TF L+ P +Q ++ YFL
Sbjct: 290 DTHTHIRVIFAGFFVNVIITFSLSCPQKSQIVSNYFL 180
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000243067 | hsapiens_gene_ensembl | Cell division
protein kinase 2 (EC 2.7.11.22) (p33 protein kinase).
[Source:Uniprot/SWISSPROT;Acc:P24941]
(264 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
01060 263 4e-71
14126 196 7e-51
01966 171 5e-45
01756 165 2e-41
32000 157 4e-39
01707 153 7e-38
20559 112 1e-30
29581 126 7e-30
04591 114 3e-26
24241 104 4e-23
18921 94 6e-20
06405 86 1e-17
04138 86 2e-17
17975 86 2e-17
03294 85 3e-17
23319 84 8e-17
00300 83 1e-16
13592 82 2e-16
03508 59 4e-16
09606 80 9e-16
12721 76 1e-14
19301 75 3e-14
03240 74 7e-14
01718 72 2e-13
11780 70 6e-13
32359 60 1e-12
12453 69 2e-12
14420 69 2e-12
27546 65 3e-11
13066 65 4e-11
21808 64 5e-11
14477 64 9e-11
09007 61 5e-10
01106 60 8e-10
15910 60 8e-10
16003 60 9e-10
21433 46 3e-09
17253 58 3e-09
31885 58 5e-09
19761 57 6e-09
36481 57 7e-09
04852 57 7e-09
00392 57 1e-08
37602 44 3e-08
19094 54 5e-08
30755 54 6e-08
27405 54 9e-08
31489 53 1e-07
14116 52 2e-07
26009 39 2e-07
11404 52 3e-07
22005 52 3e-07
18484 50 8e-07
05084 50 1e-06
29360 49 2e-06
07940 48 5e-06
21079 47 8e-06
21800 47 8e-06
16708 47 9e-06
11185 47 1e-05
13212 46 1e-05
28157 45 4e-05
26560 44 5e-05
26909 44 6e-05
31789 43 1e-04
26711 42 2e-04
00715 42 2e-04
00638 42 2e-04
12786 42 2e-04
18287 40 0.001
15549 39 0.002
28638 39 0.002
00394 39 0.002
06358 39 0.003
07291 39 0.003
07836 36 0.020
17300 35 0.031
20640 35 0.035
01392 34 0.057
18481 34 0.063
35032 33 0.082
17806 33 0.17
12672 31 0.55
17644 30 0.70
20773 30 0.86
15931 29 1.9
16350 28 3.0
20513 28 3.2
13078 28 3.6
26565 28 4.6
>01060
Length = 1800
Score = 263 bits (673), Expect = 4e-71, Method: Compositional matrix adjust.
Identities = 137/295 (46%), Positives = 177/295 (60%), Gaps = 36/295 (12%)
Frame = +1
Query: 1 MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH 60
+ + +KIGEGTYGVVYK R++ TG +A+KKIRL +GVPS+AIREI++L+EL H
Sbjct: 70 LSDLTDFQKIGEGTYGVVYKCRHRATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELRH 249
Query: 61 PNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLP--LIKSYLFQLLQGLAFC 118
NIV L DVI + +L+LVFEFL DLK ++D G+ L L+KSY+FQ++ G+ FC
Sbjct: 250 TNIVCLEDVIMEDERLFLVFEFLSMDLKMYIDKFP-EGVVLDRRLVKSYVFQIVTGIXFC 426
Query: 119 HSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVT-------------- 164
H R++HRDLKPQNLLIN GAIK+ADFG+AR F +PVR YTHEV
Sbjct: 427 HQRRIVHRDLKPQNLLINHTGAIKIADFGMARTFALPVRAYTHEVVTLWYRAPEILMGAS 606
Query: 165 --------------------RRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKP 204
R +F GDSEIDQLF+IFR +GTP E WP +P +
Sbjct: 607 KYSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKLPAFNG 786
Query: 205 SFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPV 259
FP W S+ + LD G L+ + L DP +RIS K L H +F +V V
Sbjct: 787 MFPLWKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYFLNVDTSV 951
>14126
Length = 1265
Score = 196 bits (499), Expect = 7e-51, Method: Compositional matrix adjust.
Identities = 116/294 (39%), Positives = 164/294 (55%), Gaps = 41/294 (13%)
Frame = +3
Query: 2 ENFQKVEKIGEGTYGVVYKARN-KLTGEVVALKKIRLDTETEGVPSTAIREISLLKELN- 59
+ +++V IG G YG VYKAR+ + GE VA+K+IRL+ EG+P AIREIS+LK+L
Sbjct: 189 QKYEEVAVIGNGAYGTVYKARDLRNQGEFVAMKRIRLNNTEEGMPMMAIREISMLKQLEQ 368
Query: 60 --HPNIVKLLDVIHT-----ENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLL 112
HPN+V+LLDV H E +L LVFE++ DL ++ G+ IK + QLL
Sbjct: 369 YEHPNVVRLLDVSHNTITDREIRLNLVFEYIEHDLATYLAKCPSPGLGPDRIKDLMLQLL 548
Query: 113 QGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLAR---------------------- 150
G+ F HS+R++HRDLKPQNLLI+ +G +KLADFGLAR
Sbjct: 549 NGVDFLHSNRIVHRDLKPQNLLISKDGRLKLADFGLARIYSFHMALTTVVVTLWYRSPEV 728
Query: 151 ----AFGVPVRTYTHEV------TRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMP 200
+G V ++ TRRALF G SE DQL +IF +G P WP S+
Sbjct: 729 LMQAEYGTSVDIWSCGCIFAELFTRRALFKGSSEFDQLKKIFEVIGLPPAGDWPEGVSV- 905
Query: 201 DYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQD 254
++ SF +VP +D + L+ +ML + +RIS++ +L HP+ +D
Sbjct: 906 -HRNSFRPTPPVPLQTLVPEMDPQAKDLMEKMLVFKSGRRISSRESLLHPYLRD 1064
>01966
Length = 1735
Score = 171 bits (433), Expect(2) = 5e-45, Method: Compositional matrix adjust.
Identities = 84/145 (57%), Positives = 109/145 (75%), Gaps = 2/145 (1%)
Frame = -1
Query: 21 ARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVF 80
R++ TG +A+KKIRL +GVPS+AIREI++L+EL H NIV L DVI + +L+LVF
Sbjct: 1654 CRHRATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTNIVCLEDVIMEDERLFLVF 1475
Query: 81 EFLHQDLKKFMDASALTGIPLP--LIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTE 138
EFL DLK ++D G+ L L+KSY+FQ++ G+ FCH R++HRDLKPQNLLIN
Sbjct: 1474 EFLSMDLKMYIDKFP-EGVVLDRRLVKSYVFQIVTGINFCHQRRIVHRDLKPQNLLINHT 1298
Query: 139 GAIKLADFGLARAFGVPVRTYTHEV 163
GAIK+ADFG+AR F +PVR YTHEV
Sbjct: 1297 GAIKIADFGMARTFALPVRAYTHEV 1223
Score = 27.3 bits (59), Expect(2) = 5e-45, Method: Compositional matrix adjust.
Identities = 11/14 (78%), Positives = 13/14 (92%)
Frame = -2
Query: 6 KVEKIGEGTYGVVY 19
++ KIGEGTYGVVY
Sbjct: 1698 RLSKIGEGTYGVVY 1657
Score = 85.1 bits (209), Expect = 3e-17, Method: Compositional matrix adjust.
Identities = 46/120 (38%), Positives = 62/120 (51%), Gaps = 9/120 (7%)
Frame = -3
Query: 149 ARAFGVPVRTYT------HEVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDY 202
A + PV ++ + R +F GDSEIDQLF+IFR +GTP E WP +P +
Sbjct: 1184 ASKYSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKLPAF 1005
Query: 203 KPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDV---TKPV 259
FP W S+ + LD G L+ + L DP +RIS K L H +F +V KPV
Sbjct: 1004 NGMFPLWKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYFLNVDTSVKPV 825
>01756
Length = 1858
Score = 165 bits (417), Expect = 2e-41, Method: Compositional matrix adjust.
Identities = 108/305 (35%), Positives = 162/305 (53%), Gaps = 48/305 (15%)
Frame = -3
Query: 4 FQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNI 63
++K+ KIG+GT+G V+KAR K T +VVA+KK+ +D E EG P TA+REI +L+ LNH N+
Sbjct: 1736 YEKLAKIGQGTFGEVFKARCKKTKQVVAMKKVLMDNEKEGFPITALREIKILQLLNHENV 1557
Query: 64 VKLLDVIHT--------ENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGL 115
V L+++ T ++ YLVFEF DL + ++ LP IK + QL+ GL
Sbjct: 1556 VDLIEICSTKATSANRYKSMFYLVFEFCEHDLAGLLSNMSVV-FNLPEIKEVMKQLMNGL 1380
Query: 116 AFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRT---YTHEV--------- 163
+ H +++LHRD+K N+LI +G +KLADFGLARAF V +R YT+ V
Sbjct: 1379 YYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRPPE 1200
Query: 164 -------------------------TRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTS 198
TR + G +E +QL I + G+ VWPGV
Sbjct: 1199 LLLGDRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQNQLTLITQLCGSITPEVWPGVER 1020
Query: 199 MPDYKP-SFPKWARQDFSKVVPPLDEDG--RSLLSQMLHYDPNKRISAKAALAHPFFQDV 255
+ Y P+ ++ + + +D LL ++L DP KR+++ AL+H FF
Sbjct: 1019 LELYNSLDLPQGNKRKVKERLRYYIKDAYALDLLDKLLALDPGKRVNSDEALSHDFFWMD 840
Query: 256 TKPVP 260
+P+P
Sbjct: 839 PEPLP 825
>32000
Length = 644
Score = 157 bits (397), Expect = 4e-39, Method: Compositional matrix adjust.
Identities = 79/153 (51%), Positives = 98/153 (64%), Gaps = 34/153 (22%)
Frame = -1
Query: 139 GAIKLADFGLARAFGVPVRTYTHEV----------------------------------T 164
+K+ADFGLAR FG+PVRTYTHEV T
Sbjct: 578 AKMKIADFGLARVFGLPVRTYTHEVITLWYRAPEILLGCRFYSVPVDIWSLGCIFVEMMT 399
Query: 165 RRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDED 224
RRALFPGDSEIDQL+RIFRTLGTPDE VWPGV+ +PDYKP+FPKW ++ VV L +
Sbjct: 398 RRALFPGDSEIDQLYRIFRTLGTPDEKVWPGVSKLPDYKPTFPKWPLKNLETVV-SLSKV 222
Query: 225 GRSLLSQMLHYDPNKRISAKAALAHPFFQDVTK 257
G LL +ML Y+PN+RISA++A+ HP+F D+ +
Sbjct: 221 GLDLLKRMLTYNPNRRISARSAMRHPYFNDMKR 123
>01707
Length = 757
Score = 153 bits (386), Expect = 7e-38, Method: Compositional matrix adjust.
Identities = 82/220 (37%), Positives = 123/220 (55%), Gaps = 34/220 (15%)
Frame = +1
Query: 1 MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH 60
ME ++K+ KIGEG+YGVV+K RNK T ++VA+KK + + A+REI +LK+L H
Sbjct: 61 MEKYEKIGKIGEGSYGVVFKCRNKETSQLVAIKKFVESEDDPLIKKIAMREIRMLKQLKH 240
Query: 61 PNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHS 120
PN+V+L++V + +L+LVF+++ L +D G+P P++K ++Q L + FCH
Sbjct: 241 PNLVRLIEVFRRKKRLHLVFDYVDHTLLNELDRYP-RGLPEPMVKRIIYQTLLAVNFCHQ 417
Query: 121 HRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVTRR-------------- 166
+ +HRD+KP+N+LI +G +KL DFG AR P YT V R
Sbjct: 418 YNTIHRDVKPENILITRQGQVKLCDFGFARILTGPGDEYTDYVATRWYRAPELLVGDTQY 597
Query: 167 --------------------ALFPGDSEIDQLFRIFRTLG 186
AL+PG S++DQL I +TLG
Sbjct: 598 GPPVDVWAIGCVFAELLTGQALWPGRSDVDQLHLIRKTLG 717
>20559
Length = 430
Score = 112 bits (281), Expect(3) = 1e-30, Method: Compositional matrix adjust.
Identities = 53/83 (63%), Positives = 69/83 (83%)
Frame = -2
Query: 1 MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH 60
M+ ++K+EKIGEGTYG V+KA+N+ T E+VALK++RLD + EGVPS+A+REI LLKEL H
Sbjct: 378 MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKH 199
Query: 61 PNIVKLLDVIHTENKLYLVFEFL 83
NIV+L DV+H+E KL LVF L
Sbjct: 198 RNIVRLHDVLHSERKLTLVF*IL 130
Score = 33.1 bits (74), Expect(3) = 1e-30, Method: Compositional matrix adjust.
Identities = 18/38 (47%), Positives = 23/38 (60%)
Frame = -3
Query: 80 FEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAF 117
FE+ QDLKK+ D P +KS+L QLL+GL F
Sbjct: 140 FEYCDQDLKKYFDTCNGEIDP-DTVKSFLHQLLRGLGF 30
Score = 24.3 bits (51), Expect(3) = 1e-30, Method: Compositional matrix adjust.
Identities = 9/14 (64%), Positives = 11/14 (78%)
Frame = -1
Query: 113 QGLAFCHSHRVLHR 126
+ L FCHS+ VLHR
Sbjct: 43 EDLVFCHSNNVLHR 2
>29581
Length = 1278
Score = 126 bits (317), Expect = 7e-30, Method: Compositional matrix adjust.
Identities = 80/256 (31%), Positives = 122/256 (47%), Gaps = 41/256 (16%)
Frame = -2
Query: 45 PSTAIREISLLKELNHPNIVKLLDVI--HTENKLYLVFEFLHQDLKKFMDASALTGIPLP 102
PS + L L H NIV+L +V+ + + L+LV E+ QDL AS L +P P
Sbjct: 1223 PSVVCVRSTFLLNLRHQNIVQLQEVVVGKSLDSLFLVMEYCEQDL-----ASLLDNMPAP 1059
Query: 103 L----IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRT 158
+K + QLL+GL + H ++HRDLK NLL+ +G +K+ADFGLAR +G P +
Sbjct: 1058 FSESQVKCIVLQLLKGLRYLHEAFIIHRDLKVSNLLMTDKGCVKIADFGLARNYGKPQKP 879
Query: 159 YTHEVT----------------------------------RRALFPGDSEIDQLFRIFRT 184
T +V + L PG S++ Q+ I
Sbjct: 878 MTPKVVTLWYRAPELLFGSKTHSTAIDMWSAGCILGELLGHKPLMPGRSDLQQIELIMEL 699
Query: 185 LGTPDEVVWPGVTSMPDYKP-SFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISA 243
LGTP++ +WPG + +P ++ + K + P L E G LL+ + Y P KR +A
Sbjct: 698 LGTPNDTIWPGFSQLPAFEQFTLKKQPYNNLRHTFPWLSESGIRLLNGLFMYHPQKRATA 519
Query: 244 KAALAHPFFQDVTKPV 259
+ L H +F++ P
Sbjct: 518 EDCLEHSYFKEQPYPC 471
Score = 33.5 bits (75), Expect = 0.094, Method: Compositional matrix adjust.
Identities = 14/34 (41%), Positives = 23/34 (67%)
Frame = -1
Query: 28 EVVALKKIRLDTETEGVPSTAIREISLLKELNHP 61
E+VALKK+R+ E G+P + +REI++ + P
Sbjct: 1275 EIVALKKMRMTGERYGIPISGLREINIFAQSATP 1174
>04591
Length = 1117
Score = 114 bits (286), Expect = 3e-26, Method: Compositional matrix adjust.
Identities = 84/270 (31%), Positives = 124/270 (45%), Gaps = 49/270 (18%)
Frame = -2
Query: 42 EGVPSTAIREISLLKELNHPNIVKLLDVIHTE--------NKLYLVFEFLHQDLKKFMDA 93
EG P TA+REI +L++L H N+V+L ++ HT+ + YL+FE+ DL ++
Sbjct: 1098 EGFPITALREIKILQQLEHENVVQLQEICHTQAGPYNRYKSTFYLIFEYCDYDLAGLLN- 922
Query: 94 SALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFG 153
+ L K+ + QLL GL + H+ ++LHRD+K N+L+ +G +KLADFGL+R +
Sbjct: 921 NLRVKFSLADKKNLMSQLLNGLFYIHTKQILHRDIKAANILLTRDGVLKLADFGLSRPWV 742
Query: 154 VPVRTYTHEVT---------------------------------RRALFPGDSEIDQLFR 180
R VT R+ L G SE QL
Sbjct: 741 KSKRLTNRVVTLWYRPPELLLGEREYGPEIDMWGVGCIMAEMWSRKPLMQGRSEQHQLSL 562
Query: 181 IFRTLGTPDEVVWPGVT--------SMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQM 232
I G+ + VWPGVT +P KP K D K +++G L+
Sbjct: 561 ITDLCGSLNAEVWPGVTKLELYGKLDLPQGKPRKVKERMLDLLK-----NKEGAELIDIF 397
Query: 233 LHYDPNKRISAKAALAHPFFQDVTKPVPHL 262
L DP +R++ AL+H FF P P L
Sbjct: 396 LRLDPGQRMNCDNALSHDFFWVDPLPSPSL 307
>24241
Length = 413
Score = 104 bits (259), Expect = 4e-23, Method: Compositional matrix adjust.
Identities = 56/116 (48%), Positives = 78/116 (67%), Gaps = 1/116 (0%)
Frame = -2
Query: 4 FQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPN- 62
++ KIGEGTYGVVYK R++ TG +A+KKIRL +GVPS+AIREI++L+EL H
Sbjct: 337 LDRLSKIGEGTYGVVYKCRHRATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTQX 158
Query: 63 IVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFC 118
+V L DVI + +L+LVFEFL DLK ++D G+ L L +++ G+ FC
Sbjct: 157 LVCLEDVIMEDERLFLVFEFLSMDLKMYIDKFP-EGVVLD---RRLVKIVTGINFC 2
>18921
Length = 697
Score = 94.0 bits (232), Expect = 6e-20, Method: Compositional matrix adjust.
Identities = 52/150 (34%), Positives = 90/150 (60%), Gaps = 4/150 (2%)
Frame = +2
Query: 4 FQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNI 63
F + K+GEG+YG V+K+ +K TG+V+A+K++ +DT+ + + I+EIS++++ + I
Sbjct: 35 FDILGKLGEGSYGSVFKSLHKETGQVLAIKQVPVDTDLQEI----IKEISIMQQCDSKYI 202
Query: 64 VKLLDVIHTENKLYLVFEFLH----QDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCH 119
VK L++V E+ D+ + + + + I + L+ L+GL + H
Sbjct: 203 VKYYGSYFKNTDLWIVMEYCGAGSVSDIMRLRNKTLVE----REIATILYYTLKGLXYLH 370
Query: 120 SHRVLHRDLKPQNLLINTEGAIKLADFGLA 149
S R +HRD+K N+L+N EG KLADFG+A
Sbjct: 371 SRRKIHRDIKAGNILLNNEGHAKLADFGVA 460
>06405
Length = 1965
Score = 86.3 bits (212), Expect = 1e-17, Method: Compositional matrix adjust.
Identities = 48/143 (33%), Positives = 80/143 (55%), Gaps = 1/143 (0%)
Frame = +1
Query: 9 KIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLD 68
++G G YG VY+A K ++VA+K ++ DT + + E +++KE+ HPN+V+LL
Sbjct: 280 RLGGGQYGDVYEAMWKRYNKIVAVKTLKEDTMAL---NDFLEEAAIMKEMKHPNLVQLLG 450
Query: 69 VIHTENKLYLVFEFL-HQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRD 127
V E Y+V EF+ H +L ++ +S + Q+ G+A+ + +HRD
Sbjct: 451 VCTREPPFYIVTEFMPHGNLLDYLRSSTREENGPTALMYMATQIASGMAYLETKNFIHRD 630
Query: 128 LKPQNLLINTEGAIKLADFGLAR 150
L +N L+ +K+ADFGLAR
Sbjct: 631 LAARNCLVADSNMVKVADFGLAR 699
>04138
Length = 800
Score = 85.5 bits (210), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 61/188 (32%), Positives = 86/188 (45%), Gaps = 44/188 (23%)
Frame = +1
Query: 115 LAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRT---YTHEV-------- 163
L + H +++LHRD+K N+LI +G +KLADFGLARAF V +R YT+ V
Sbjct: 52 LYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRPP 231
Query: 164 --------------------------TRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVT 197
TR + G +E +QL I + G+ VWPGVT
Sbjct: 232 ELLLGDRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQNQLTLITQLCGSITPEVWPGVT 411
Query: 198 SMPDYKPSFPKWA-------RQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHP 250
+ Y A R F++++ D G L ++L DP++RISA AL H
Sbjct: 412 QLSMYHQIKGALAAGRKNIIRDRFARILK--DPYGLDLFERLLKMDPSQRISADEALNHD 585
Query: 251 FFQDVTKP 258
FF +P
Sbjct: 586 FFWVGVEP 609
>17975
Length = 449
Score = 85.5 bits (210), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 50/137 (36%), Positives = 80/137 (58%), Gaps = 2/137 (1%)
Frame = +3
Query: 15 YGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTEN 74
+ VV AR+ TGE VA+K I E S +E+ +K + HPN+V+L +VI T+
Sbjct: 6 FAVVKLARHVFTGEKVAVKVIDKTKLDEVSRSHLFQEVRCMKLVQHPNVVRLYEVIDTQT 185
Query: 75 KLYLVFEFLH-QDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNL 133
KLYL+ E D+ ++ + G+ L K Y Q+++ +++CH V+HRDLKP+N+
Sbjct: 186 KLYLILELGDGGDMYDYIMRHS-GGLEEKLAKRYFRQIVEAISYCHKLHVVHRDLKPENV 362
Query: 134 LINTE-GAIKLADFGLA 149
+ + G +KL DFG +
Sbjct: 363 VFFEKPGLVKLTDFGFS 413
>03294
Length = 1684
Score = 85.1 bits (209), Expect = 3e-17, Method: Compositional matrix adjust.
Identities = 43/104 (41%), Positives = 57/104 (54%), Gaps = 3/104 (2%)
Frame = -1
Query: 159 YTHEVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVV 218
+ + R +F GDSEIDQLF+IFR +GTP E WP +P + FP W S+ +
Sbjct: 1645 FADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKLPAFNGMFPLWKEGKLSETL 1466
Query: 219 PPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDV---TKPV 259
LD G L+ + L DP +RIS K L H +F +V KPV
Sbjct: 1465 TDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYFLNVDTSVKPV 1334
>23319
Length = 2235
Score = 83.6 bits (205), Expect = 8e-17, Method: Compositional matrix adjust.
Identities = 43/91 (47%), Positives = 59/91 (64%), Gaps = 1/91 (1%)
Frame = +3
Query: 166 RALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKW-ARQDFSKVVPPLDED 224
R LFPG+ + DQL RIF+ LGTP E WPG+T +P+Y+ FP + + +VVP L+
Sbjct: 90 RPLFPGNDDDDQLKRIFKLLGTPTEDQWPGMTQLPNYR-MFPMYHVTTTWQQVVPKLNSK 266
Query: 225 GRSLLSQMLHYDPNKRISAKAALAHPFFQDV 255
GR LL +L P+ R+SA AL HP+F D+
Sbjct: 267 GRDLLQCLLVCCPSDRMSADEALQHPYFADL 359
>00300
Length = 2318
Score = 82.8 bits (203), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 43/146 (29%), Positives = 79/146 (54%)
Frame = -1
Query: 4 FQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNI 63
+Q+ KIGEG +G VY A N TGE++ALK+++ EI + + + H N+
Sbjct: 1652 WQRGNKIGEGQFGKVYTAVNMSTGELMALKEMKFQPNDLQQLREMCDEIKIFEGIQHENL 1473
Query: 64 VKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRV 123
VK V ++++ + E+ ++ +A G+P LI+ Y +++ + H + +
Sbjct: 1472 VKYYGVEVHKDEMLMFMEYCDTGT---IEEAAKMGLPEYLIRRYTREIVLAVNHLHENSI 1302
Query: 124 LHRDLKPQNLLINTEGAIKLADFGLA 149
+HRD+K N+ + + G +KL DFG +
Sbjct: 1301 VHRDIKGANIFLTSNGHVKLGDFGCS 1224
>13592
Length = 980
Score = 82.4 bits (202), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 69/266 (25%), Positives = 122/266 (45%), Gaps = 21/266 (7%)
Frame = +2
Query: 9 KIGEGTYGVVYKARNKLTGEVVALKKIRLD-TETEGVPSTAIREISLLKELNHPNIVKLL 67
KIG+G +G VY A N TGE++A+K+I + ET + + A E+ +L+ + H N+V+
Sbjct: 5 KIGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETRALKNVA-EELKILEGIKHKNLVRYY 181
Query: 68 DV-IHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHR 126
+ +H E L + L+ ++ + G+P L + + QLL G+A H H ++HR
Sbjct: 182 GIEVHREELLIFMELCSEGTLESLVELTG--GLPEALSRRFTAQLLSGVAELHKHGIVHR 355
Query: 127 DLKPQNL-LINTEGAIKLADFGLARAF----GVPVRTYTHEVTRRALFPGDSEIDQLFRI 181
D+K N+ L++ ++KL DFG A VP + T+ + P ++F
Sbjct: 356 DIKTANIFLVDGSNSLKLGDFGSAVKIQAHTTVPGELQGYVGTQAYMAP------EVFTK 517
Query: 182 FRTLGTPDEV-VWPGVTSMPDYKPSFPKWARQDFS-------------KVVPPLDEDGRS 227
+ G +W + + WA+ D + + L ++G
Sbjct: 518 TNSDGHGRLADIWSVGCVVVEMASGKRPWAQFDSNFQIMFKVGMGEKPQAPESLSQEGHD 697
Query: 228 LLSQMLHYDPNKRISAKAALAHPFFQ 253
+ L +DP +R+SA L F +
Sbjct: 698 FIDHCLQHDPKQRLSAIELLEQNFCK 775
>03508
Length = 1463
Score = 58.5 bits (140), Expect(2) = 4e-16, Method: Compositional matrix adjust.
Identities = 48/169 (28%), Positives = 78/169 (46%), Gaps = 4/169 (2%)
Frame = +1
Query: 2 ENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHP 61
+++Q V K+G G Y V++A N E K + + L
Sbjct: 589 DDYQIVRKLGRGKYSEVFEAINVTNNE----KCVIKILKPVKKKKIKREIKILENLRGGT 756
Query: 62 NIVKLLDVIH--TENKLYLVFEFLHQ-DLKKFMDASALTGIPLPLIKSYLFQLLQGLAFC 118
N++ LL ++ L+FE ++ D K+ T I+ YL++L++ L FC
Sbjct: 757 NVITLLAIVKDPVSRTPALIFEHVNNTDFKQLY--QTFTDYD---IRFYLYELMKALDFC 921
Query: 119 HSHRVLHRDLKPQNLLINTEG-AIKLADFGLARAFGVPVRTYTHEVTRR 166
HS ++HRD+KP N++I+ E ++L D+GLA F P Y V R
Sbjct: 922 HSMGIMHRDVKPHNVMIDHENKKLRLIDWGLAE-FYHPGMEYNVRVASR 1065
Score = 43.1 bits (100), Expect(2) = 4e-16, Method: Compositional matrix adjust.
Identities = 28/94 (29%), Positives = 43/94 (45%), Gaps = 9/94 (9%)
Frame = +2
Query: 168 LFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSF---------PKWARQDFSKVV 218
F G DQL RI + LGT D + + D P F +W R S+
Sbjct: 1175 FFHGHDNYDQLVRIAKVLGTDDLYGYIEKYQI-DLDPRFNDILGRHSRKRWERFVHSENQ 1351
Query: 219 PPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFF 252
+ + L ++L YD N+R++A+ A+ HP+F
Sbjct: 1352 HLISPEALDFLDKLLRYDHNERLTAREAMDHPYF 1453
>09606
Length = 1300
Score = 80.1 bits (196), Expect = 9e-16, Method: Compositional matrix adjust.
Identities = 49/154 (31%), Positives = 78/154 (50%), Gaps = 1/154 (0%)
Frame = -3
Query: 1 MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH 60
MENF E++G+G + ++YK R K T VA+ I E + + +++H
Sbjct: 1118 MENFVLYEELGKGEHSIIYKGRRKGTINFVAIHCIEKCKRPE-----VTNTVRMTHDISH 954
Query: 61 PNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTG-IPLPLIKSYLFQLLQGLAFCH 119
PN+V+ + T N L+LV E D A +P I+ + L+ GL + H
Sbjct: 953 PNVVQFHEWYETSNHLWLVVELCTGG--SLADILAQDHHLPETSIRDFGIHLVTGLHYIH 780
Query: 120 SHRVLHRDLKPQNLLINTEGAIKLADFGLARAFG 153
S +L DL+P +L++T G +K ADFGL++ G
Sbjct: 779 SLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEG 678
>12721
Length = 821
Score = 76.3 bits (186), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 68/255 (26%), Positives = 117/255 (45%), Gaps = 20/255 (7%)
Frame = +1
Query: 9 KIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLD 68
KIGEG+ G+V A ++ G +A+KK +D + E+ ++++ +HPNIV++ +
Sbjct: 109 KIGEGSTGIVCIATSR-DGRQMAVKK--MDLRKQQRRELLFNEVVVMRDYHHPNIVEMYN 279
Query: 69 VIHTENKLYLVFEFLHQDLKKFMDASALTGIPLP------LIKSYLFQLLQGLAFCHSHR 122
++L++V EF M+ ALT I I + L+ LAF H++
Sbjct: 280 SYLVNDELWVVMEF--------MEGGALTDIVTNNRMDEVQIATVCRACLKALAFLHANG 435
Query: 123 VLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVTRRALFPGDSEIDQLFRIF 182
V+HRD+K ++L++ +G +KL DFG T ++ +R G I
Sbjct: 436 VIHRDIKSDSILLSHDGKVKLXDFGFCAQV-------TQDLQKRKSLVGTPYWMAPEVIS 594
Query: 183 RTLGTPDEVVWP---GVTSMPDYKPSF----PKWARQDFSKVVPP-------LDEDGRSL 228
R P+ +W V M D +P F P A + + PP + +
Sbjct: 595 RLPYGPEVDIWSLGIMVMEMIDAEPPFFNEPPLQAMRRIRDMPPPKLRNTHKISPRLQGF 774
Query: 229 LSQMLHYDPNKRISA 243
+ +ML DP++R +A
Sbjct: 775 IDRMLVRDPHQRATA 819
>19301
Length = 712
Score = 75.1 bits (183), Expect = 3e-14, Method: Compositional matrix adjust.
Identities = 47/150 (31%), Positives = 75/150 (50%), Gaps = 2/150 (1%)
Frame = +2
Query: 2 ENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHP 61
E+ +E +G G G V+ KL E VA+KK+R ET+ I L++LNHP
Sbjct: 305 ESITDLEWLGSGAQGAVF--LGKLCAEEVAVKKVRDIKETD---------IRNLRKLNHP 451
Query: 62 NIVKLLDVIHTENKLYLVFEFL--HQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCH 119
NI+ V ++ E+ Q + D IP L+ + Q+ G+ + H
Sbjct: 452 NIISFKGVCTQAPCYCIIMEYCPYGQLYEVLRDGKE---IPPALVLDWSKQIASGMNYLH 622
Query: 120 SHRVLHRDLKPQNLLINTEGAIKLADFGLA 149
SH+++HRDLK N+L+ +K++DFG +
Sbjct: 623 SHKIIHRDLKSPNVLVAKNDVVKISDFGTS 712
>03240
Length = 1683
Score = 73.9 bits (180), Expect = 7e-14, Method: Compositional matrix adjust.
Identities = 48/151 (31%), Positives = 76/151 (50%), Gaps = 2/151 (1%)
Frame = -3
Query: 4 FQKVEKIGEGTYGVVYKARNKLTGEVVALKKIR-LDTETEGVPSTAIREISLLKELNHPN 62
F+K++ +G G +G V R TG + A+K +R D + E +L E ++
Sbjct: 1285 FEKIKTLGVGAFGEVSLCRKNDTGMLYAMKTLRKSDVLKRNQVAHVKAERDILAEADNEW 1106
Query: 63 IVKLLDVIHTENKLYLVFEFL-HQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSH 121
+VKL N LY V +++ DL + + + PL + Y+ +L+Q + H
Sbjct: 1105 VVKLYYSFQDHNYLYFVMDYVPGGDLMGLLIRMEI--LDEPLARFYVAELVQAIESVHRM 932
Query: 122 RVLHRDLKPQNLLINTEGAIKLADFGLARAF 152
+HRD+KP N+LI+ G IKL DFGL F
Sbjct: 931 GFIHRDIKPDNILIDRNGHIKLTDFGLCTGF 839
>01718
Length = 959
Score = 72.4 bits (176), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 49/148 (33%), Positives = 80/148 (54%), Gaps = 5/148 (3%)
Frame = +3
Query: 7 VEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKL 66
EKIG G + V+K +++TG+V+ALK ++T T +RE+ LL L H NI++
Sbjct: 162 CEKIGAGFFSEVFKVTHRITGQVMALK---MNTMTSN-RHNMLREVQLLNRLQHANILRF 329
Query: 67 LDVIHTENKLYLVFEFL-HQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLH 125
+ V E +L+ + E++ +L++ ++ +P L +GL + HS R +H
Sbjct: 330 MGVCVHEGQLHALTEYIPSGNLEQLLEKKD-EELPWTQRIQLTLGLARGLDYLHSTRFIH 506
Query: 126 RDLKPQNLLINTEGA----IKLADFGLA 149
RDL +N+LI E +ADFGLA
Sbjct: 507 RDLTSKNILIRREDNHGYHAVIADFGLA 590
>11780
Length = 1713
Score = 70.5 bits (171), Expect = 6e-13, Method: Compositional matrix adjust.
Identities = 45/147 (30%), Positives = 86/147 (58%), Gaps = 1/147 (0%)
Frame = +3
Query: 8 EKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLL 67
E IG+G +G VYK + G+ VA+K+++ E + ++E S++ L H N+V+L+
Sbjct: 615 EAIGKGDFGDVYKGMYR--GQPVAIKQLKDKDRGE---QSFLQEASVMTSLRHDNLVRLI 779
Query: 68 DVIHTENKLYLVFEFLHQ-DLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHR 126
V+ E ++LV EF+ + +L +++ + + I ++ + + S R++HR
Sbjct: 780 GVVLGET-IFLVTEFMGKGNLVEYLRSRGRSVITKKDQINFATDTCAAMEYLESKRLVHR 956
Query: 127 DLKPQNLLINTEGAIKLADFGLARAFG 153
DL +N+L++ +G K++DFGLA+ FG
Sbjct: 957 DLAARNVLVHDDGKAKVSDFGLAK-FG 1034
>32359
Length = 928
Score = 60.5 bits (145), Expect(2) = 1e-12, Method: Compositional matrix adjust.
Identities = 39/120 (32%), Positives = 67/120 (55%), Gaps = 8/120 (6%)
Frame = -1
Query: 10 IGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDV 69
IG G++GVVY+A+ T E+VA+KK+ D + RE+ ++++L H NIVKL
Sbjct: 406 IGNGSFGVVYQAKLVDTSELVAIKKVLQDKRFKN------RELQIMRKLEHQNIVKLKFF 245
Query: 70 IHTENK------LYLVFEFLHQDLKKFMD--ASALTGIPLPLIKSYLFQLLQGLAFCHSH 121
++ + L LV E++ + + + + + IP+ IK Y++QL + LA+ HS
Sbjct: 244 FYSSGEKKDEVFLNLVLEYVPETVYRVARHYSKSKQTIPILYIKLYMYQLFRSLAYIHSQ 65
Score = 28.9 bits (63), Expect(2) = 1e-12, Method: Compositional matrix adjust.
Identities = 11/19 (57%), Positives = 15/19 (78%)
Frame = -3
Query: 123 VLHRDLKPQNLLINTEGAI 141
V HRD+KPQNLL++ E +
Sbjct: 62 VCHRDIKPQNLLLDPETGV 6
>12453
Length = 680
Score = 69.3 bits (168), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 35/91 (38%), Positives = 51/91 (56%), Gaps = 1/91 (1%)
Frame = +3
Query: 166 RALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKP-SFPKWARQDFSKVVPPLDED 224
R LFPG + D+L IF+TLGTP E P ++ PD+ + P + + + P LD D
Sbjct: 39 RPLFPGSTVEDELHLIFKTLGTPTEDSLPSISRNPDFLALNLPHYQGEALITIAPRLDSD 218
Query: 225 GRSLLSQMLHYDPNKRISAKAALAHPFFQDV 255
G LL++ L Y+ R+SA +L H FF +
Sbjct: 219 GLDLLAKFLKYNAKIRVSAADSLKHSFFNSL 311
>14420
Length = 528
Score = 68.9 bits (167), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 42/133 (31%), Positives = 62/133 (46%), Gaps = 11/133 (8%)
Frame = +2
Query: 49 IREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYL 108
I EI +++E +PNIV LD +L++V EFL D T + I +
Sbjct: 44 INEILVMRENQNPNIVNYLDSYLVGEELWVVMEFLAGG--SLTDVVTETCMDEGQIAAVC 217
Query: 109 FQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAF-----------GVPVR 157
+ LQ L F H ++V+HRD+K N+L+ +G++KL DFG G P
Sbjct: 218 RECLQALEFLHENQVIHRDIKSDNILLGMDGSVKLTDFGFCAQLSPEQSKRSTMVGTPYW 397
Query: 158 TYTHEVTRRALFP 170
VTR+ P
Sbjct: 398 MAPEVVTRKQYGP 436
>27546
Length = 426
Score = 65.1 bits (157), Expect = 3e-11, Method: Compositional matrix adjust.
Identities = 33/102 (32%), Positives = 58/102 (56%), Gaps = 1/102 (0%)
Frame = -1
Query: 50 REISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTG-IPLPLIKSYL 108
RE+ +L L+HPNI+++ ++ K+++ + + + TG I K +
Sbjct: 333 RELEILTRLDHPNIIQIHSILQRGPKIFIFMRYAEKG--DMLSHIKKTGPIDEAQTKVWF 160
Query: 109 FQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLAR 150
FQ+ + L + HSH + HRDLK +N+L++ +K+ADFG AR
Sbjct: 159 FQMAKALQYLHSHDIAHRDLKCENILLSKRLNVKIADFGFAR 34
>13066
Length = 551
Score = 64.7 bits (156), Expect = 4e-11, Method: Compositional matrix adjust.
Identities = 41/140 (29%), Positives = 73/140 (52%), Gaps = 1/140 (0%)
Frame = +3
Query: 13 GTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHT 72
GT+ Y KL +++ +K +D + P RE+ LL +L+HP I+++ ++
Sbjct: 24 GTFNDGYGRNIKLACKIIDKEKAPVDFVEKFFP----RELDLLTKLDHPYIIQIHSILQR 191
Query: 73 ENKLYLVFEFLHQ-DLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQ 131
K ++ F + DL ++ + K + +Q+ L + HS+ V HRDLK +
Sbjct: 192 XPKNFIFMRFAERGDLLTYIQEVGF--VKEKQAKIWFYQMTTALNYLHSYDVAHRDLKCE 365
Query: 132 NLLINTEGAIKLADFGLARA 151
N+L+++ +KLADFG A A
Sbjct: 366 NILLSSHFNVKLADFGFACA 425
>21808
Length = 1011
Score = 64.3 bits (155), Expect = 5e-11, Method: Compositional matrix adjust.
Identities = 39/142 (27%), Positives = 74/142 (52%), Gaps = 1/142 (0%)
Frame = +1
Query: 30 VALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFL-HQDLK 88
VA+K ++ T P + E ++K+L HP +++L V ++ ++++ E + + L
Sbjct: 28 VAIKTLKSGTMD---PKDFLAEAQIMKKLRHPKLIQLYAVCTQDDPIFIITELMKNGSLL 198
Query: 89 KFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGL 148
+F+ + LP + Q+ G+A+ S +HRDL +N+L++ +K+ADFGL
Sbjct: 199 EFLQGKGRV-LKLPALIDIGAQIACGMAYLESQNYIHRDLAARNILVSDNNTVKIADFGL 375
Query: 149 ARAFGVPVRTYTHEVTRRALFP 170
AR ++ +E A FP
Sbjct: 376 ARV----IKEDEYEARVGARFP 429
>14477
Length = 493
Score = 63.5 bits (153), Expect = 9e-11, Method: Compositional matrix adjust.
Identities = 45/154 (29%), Positives = 83/154 (53%), Gaps = 3/154 (1%)
Frame = -1
Query: 9 KIGEGTYGVVYKARNKLTG-EV-VALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKL 66
K+G G +G V K +L E+ VA+K ++ V S I+E ++K+++H +IV+L
Sbjct: 469 KLGAGNFGSVMKGVCRLDDREIPVAIKVLKNADLDPSVQSELIKEAEVMKKMDHMHIVRL 290
Query: 67 LDVIHTENKLYLVFEFLHQD-LKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLH 125
+ + E + LV E L KF+ + +PL I ++Q+ QG+ + +++ +H
Sbjct: 289 IGLCEGET-MMLVLELAKLGPLNKFLPKN--KHLPLWNILELMWQVSQGMEYLEANKFVH 119
Query: 126 RDLKPQNLLINTEGAIKLADFGLARAFGVPVRTY 159
RDL +N+L+ E K++DFG+++ Y
Sbjct: 118 RDLAARNILLCDEHFAKISDFGMSKTLSRENNYY 17
>09007
Length = 1440
Score = 60.8 bits (146), Expect = 5e-10, Method: Compositional matrix adjust.
Identities = 40/166 (24%), Positives = 84/166 (50%), Gaps = 9/166 (5%)
Frame = -1
Query: 8 EKIGEGTYGVVYKA------RNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHP 61
+ +G+G +G V +A K+ V L K ++ + + ++E ++++ L+H
Sbjct: 861 KSLGQGHFGTVRQAIWTAESGEKVQVAVKCLSKDKIHKDGQEF----LKETAIMQMLDHE 694
Query: 62 NIVKLLDVIHTENK-LYLVFEF--LHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFC 118
NIV++ V+ + LV E + L+ + SA +P + + Q+ G+++
Sbjct: 693 NIVRVYGVVMDNGADIMLVTELAPMRSLLECVKEVSARVDFSVPRLCDFSQQVCDGMSYL 514
Query: 119 HSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVT 164
S R++HRDL +N+L+ ++ +K++D G++ A G Y + T
Sbjct: 513 ESKRLVHRDLAARNILLFSKSKVKISDVGVSGALGAGKEYYQSQQT 376
>01106
Length = 878
Score = 60.5 bits (145), Expect = 8e-10, Method: Compositional matrix adjust.
Identities = 42/148 (28%), Positives = 75/148 (50%), Gaps = 13/148 (8%)
Frame = +3
Query: 4 FQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNI 63
+ + K+G G + V+ + VALK ++ + TA+ E+ LLK + ++
Sbjct: 324 YHVIRKLGWGHFSTVWLCWDLTCKRFVALKVVK---SAQHYTETALDEVKLLKCVRESDV 494
Query: 64 --------VKLLDVIHTEN----KLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQL 111
V+LLD + +VFE L +L K + S GIP+ +K + Q+
Sbjct: 495 ADPARAKCVQLLDDFKISGVNGTHVAMVFEVLGYNLLKLIIRSNYQGIPIHNVKLIIRQV 674
Query: 112 LQGLAFCHSH-RVLHRDLKPQNLLINTE 138
L+GL++ H+ R++H D+KP+N+LI +
Sbjct: 675 LEGLSYMHAKCRIIHTDIKPENILICVD 758
>15910
Length = 1361
Score = 60.1 bits (144), Expect = 8e-10, Method: Compositional matrix adjust.
Identities = 46/172 (26%), Positives = 83/172 (48%), Gaps = 18/172 (10%)
Frame = +2
Query: 111 LLQGLAFCHSHRVLHRDLKPQNLL---INTEGAIKLADFGLARAFGVPVRTYTHEVTRRA 167
+L G+ + H++ V+HRDLKP+NLL + + +KLADFGL+R V+ T T
Sbjct: 491 ILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLADFGLSRIIEPEVQMSTVCGTPGY 670
Query: 168 LFPGDSEIDQLFRIFRTLGTPDEVVWP-GVTS---MPDYKPSFPKWARQDFSKVV----- 218
P + D+ TP +W GV + + Y+P F + + + K++
Sbjct: 671 CAPEVLKGDKY--------TPSVDMWSVGVIAYILLCGYEPFFAENEFEMYRKIIKGEYK 826
Query: 219 ------PPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL 264
+ E+ + ++ ++L DP KR++A AL P+ + V ++ +
Sbjct: 827 FDEEYWSEISENAKDVVRKLLVIDPKKRLTATEALRLPWVKGVATKTTNMEI 982
>16003
Length = 926
Score = 60.1 bits (144), Expect = 9e-10, Method: Compositional matrix adjust.
Identities = 38/98 (38%), Positives = 54/98 (55%)
Frame = -1
Query: 163 VTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLD 222
+ R PGD+++DQL +IF LGTP E WP VTS+PDY F +Q ++
Sbjct: 923 LIRLPFLPGDTDLDQLGKIFNMLGTPTETEWPAVTSLPDYI-QFKHCQKQPLKEIFTAAG 747
Query: 223 EDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP 260
+D LL ++L +P R +A AL P+F + KP P
Sbjct: 746 DDLLELLDKLLAMNPLHRCTATQALKMPYFSN--KPYP 639
>21433
Length = 590
Score = 46.2 bits (108), Expect(2) = 3e-09, Method: Compositional matrix adjust.
Identities = 21/44 (47%), Positives = 33/44 (75%)
Frame = +2
Query: 106 SYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLA 149
Y++QL L +CH +V+HRD+KP+NLL+ +G +K+ADFG +
Sbjct: 179 CYIYQLSSALEYCHYRKVIHRDIKPENLLLGLKGDLKIADFGWS 310
Score = 32.0 bits (71), Expect(2) = 3e-09, Method: Compositional matrix adjust.
Identities = 12/33 (36%), Positives = 20/33 (60%)
Frame = +3
Query: 50 REISLLKELNHPNIVKLLDVIHTENKLYLVFEF 82
REI + L H NI+++ H + ++YL+ EF
Sbjct: 15 REIEIQSHLRHDNILRMFGYFHDKTRVYLILEF 113
>17253
Length = 483
Score = 58.2 bits (139), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 36/128 (28%), Positives = 67/128 (52%), Gaps = 12/128 (9%)
Frame = -1
Query: 38 DTETEGVPSTAIREISLLKEL-NHPNIVKLLDVIHTENKLYLVFEFL-HQDLKKFM---- 91
+ T+ S +RE+S++++L HPN+V + + ++ EF H DL F+
Sbjct: 438 EAATDAEKSEFLRELSIMRKLPRHPNVVSFMGCCTMSDPALILMEFCCHGDLLSFLRKRR 259
Query: 92 -DASA-LTGIPLPLIK----SYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLAD 145
D + LT L S+ + +G+A +++++HRD+ +N+LI+ K++D
Sbjct: 258 PDRTVFLTSTANDLTARDFFSFALHVARGMAHVANNKIVHRDVAARNVLISERNVCKVSD 79
Query: 146 FGLARAFG 153
FGL+R G
Sbjct: 78 FGLSRRVG 55
>31885
Length = 529
Score = 57.8 bits (138), Expect = 5e-09, Method: Compositional matrix adjust.
Identities = 32/99 (32%), Positives = 52/99 (52%), Gaps = 1/99 (1%)
Frame = -2
Query: 52 ISLLKELNHPNIVKLLDVIHTENKLYLVFE-FLHQDLKKFMDASALTGIPLPLIKSYLFQ 110
+ +L L+HP +V L E L++V + FL DL+ M +K YL Q
Sbjct: 519 VDMLTRLDHPFLVNLWYAFQDEEDLFMVVDLFLGGDLRYHMQQEV--SFREDCVKFYLCQ 346
Query: 111 LLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLA 149
L L + S +++HRD+KP N+L++ +G + DF +A
Sbjct: 345 LALVLDYLRSQKIVHRDIKPDNILLDEQGHCHVTDFNIA 229
>19761
Length = 473
Score = 57.4 bits (137), Expect = 6e-09, Method: Compositional matrix adjust.
Identities = 28/68 (41%), Positives = 39/68 (57%), Gaps = 2/68 (2%)
Frame = -3
Query: 98 GIPLPLIKSYLFQLLQGLAFCHSHR--VLHRDLKPQNLLINTEGAIKLADFGLARAFGVP 155
G+P LI +L Q L + H+H +LHRDLKPQN+ + +G ++L D GLAR P
Sbjct: 435 GLPERLIVCWLMQTASALNYMHTHTPVILHRDLKPQNIYVTEKGDVRLGDLGLARKLTGP 256
Query: 156 VRTYTHEV 163
T +V
Sbjct: 255 ADFATSQV 232
>36481
Length = 806
Score = 57.0 bits (136), Expect = 7e-09, Method: Compositional matrix adjust.
Identities = 35/130 (26%), Positives = 66/130 (50%), Gaps = 6/130 (4%)
Frame = +2
Query: 11 GEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPN------IV 64
GEGT+G V + ++ L G+ +ALK I+ + A EI++L++L + V
Sbjct: 389 GEGTFGKVVQCKDLLKGDDIALKIIK---NVDKYREAAKLEINVLEKLREKDPHAKHMCV 559
Query: 65 KLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVL 124
++LD + + F L + F+ ++ P+ ++ +QL + F H +++
Sbjct: 560 QMLDWFDYHGHVCISFHMLGLSVFDFLKDNSYGAYPIEQVRHISYQLCYAVNFLHENQLT 739
Query: 125 HRDLKPQNLL 134
H DLKP+N+L
Sbjct: 740 HTDLKPENIL 769
>04852
Length = 1462
Score = 57.0 bits (136), Expect = 7e-09, Method: Compositional matrix adjust.
Identities = 41/149 (27%), Positives = 72/149 (48%), Gaps = 28/149 (18%)
Frame = +1
Query: 30 VALKKIRLDTETEGVPSTAIREISLLKEL----NHPNIVKLLDVIHTENKLYLVFEFL-H 84
VA+K +R D T ++E+ ++K + +H NIV L L+++ EF +
Sbjct: 28 VAVKMLR-DIVTAVEEQDFVQELQVMKAVKKMGSHINIVNFLGCCTQGGPLWVIVEFAKN 204
Query: 85 QDLKKFMDAS--ALTG---------------------IPLPLIKSYLFQLLQGLAFCHSH 121
+L+ F+++ + G I + SY FQ+ +G+ F S
Sbjct: 205 GNLRDFLESCRDGINGYGKFVSPQDPGWYTKTPGGHVIRRKNLLSYAFQIARGMEFLASR 384
Query: 122 RVLHRDLKPQNLLINTEGAIKLADFGLAR 150
+ +HRDL +N+L+ E +K+ADFGL+R
Sbjct: 385 KCIHRDLAARNVLVTEEHVLKIADFGLSR 471
>00392
Length = 668
Score = 56.6 bits (135), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 39/112 (34%), Positives = 58/112 (51%), Gaps = 13/112 (11%)
Frame = +3
Query: 51 EISLLKELNHPNIVKLLDVIHTENK-----LYLVFEFLHQD-----LKKFMDASALTGIP 100
E +LKEL HPNIV+ D N + LV E + LK+F +
Sbjct: 81 EAEMLKELQHPNIVRFFDYWEEHNHRNRKVIILVTELMTSGTLKTYLKRFKKPN------ 242
Query: 101 LPLIKSYLFQLLQGLAFCHSHR--VLHRDLKPQNLLINT-EGAIKLADFGLA 149
+ ++K++ Q+L+GL F H+ V+HRDLK N+ I G++K+ D GLA
Sbjct: 243 VKILKNWCRQVLKGLYFLHTRTPPVIHRDLKCDNIFITGPTGSVKIGDLGLA 398
>37602
Length = 804
Score = 43.5 bits (101), Expect(2) = 3e-08, Method: Compositional matrix adjust.
Identities = 30/91 (32%), Positives = 43/91 (47%), Gaps = 2/91 (2%)
Frame = -1
Query: 58 LNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPL--PLIKSYLFQLLQGL 115
+N V D KL++ E+ D +TG PL P I + L+GL
Sbjct: 348 VNIQTFVGYFDSYLRREKLWIAMEYCGGG--SMQDIYHVTG-PLTEPQIAFVCRETLKGL 178
Query: 116 AFCHSHRVLHRDLKPQNLLINTEGAIKLADF 146
+ H +HRD+K N+L+ EG +KLADF
Sbjct: 177 HYLHRRGKMHRDIKGANILLTEEGDVKLADF 85
Score = 30.8 bits (68), Expect(2) = 3e-08, Method: Compositional matrix adjust.
Identities = 10/22 (45%), Positives = 19/22 (86%)
Frame = -2
Query: 1 MENFQKVEKIGEGTYGVVYKAR 22
+++F+ ++++G GTYG VYKA+
Sbjct: 512 LDDFELIQRVGSGTYGDVYKAK 447
>19094
Length = 898
Score = 54.3 bits (129), Expect = 5e-08, Method: Compositional matrix adjust.
Identities = 24/46 (52%), Positives = 33/46 (71%)
Frame = +1
Query: 104 IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLA 149
I + L+ L+GL + HS R +HRD+K N+L+N EG KLADFG+A
Sbjct: 64 IATILYYTLKGL*YLHSRRKIHRDIKAGNILLNNEGHAKLADFGVA 201
>30755
Length = 1137
Score = 54.3 bits (129), Expect = 6e-08, Method: Compositional matrix adjust.
Identities = 46/162 (28%), Positives = 75/162 (46%), Gaps = 12/162 (7%)
Frame = +2
Query: 107 YLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLAR---AFGVPVRTYTHEV 163
Y +++ L + HS +++RDLK +NLL++ +G IK+ADFGL + +G +T+
Sbjct: 47 YGAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCKEDITYGRTTKTFCG-- 220
Query: 164 TRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMP----DYKPSFPKWARQDFSKVVP 219
T L P + + R GT + +P D+ F +D K
Sbjct: 221 TPEYLAPEVLDDNDYGRAVDWWGTGVVMYEMICGRLPFYNRDHDVLFTLILVEDV-KFPR 397
Query: 220 PLDEDGRSLLSQMLHYDPNKRISA-----KAALAHPFFQDVT 256
+ ++ +SLLS +L DP R+ K AHPFF +
Sbjct: 398 NITDEAKSLLSGLLAKDPRNRLGGGQDDVKEIQAHPFFASIN 523
>27405
Length = 532
Score = 53.5 bits (127), Expect = 9e-08, Method: Compositional matrix adjust.
Identities = 39/144 (27%), Positives = 73/144 (50%), Gaps = 6/144 (4%)
Frame = -3
Query: 15 YGVVYKARNKLTGEVVALKKI-RLDTETEGVPSTAIREISLLKELN----HPNIVKLLDV 69
+G VY R TG++ A+K + + + +G + A+ E +L ++ P IV +
Sbjct: 527 FGEVYGCRKADTGKMYAMKCLDKKRIKMKGGETLALNERIMLSLVSTGEGSPFIVCMTYA 348
Query: 70 IHTENKLYLVFEFLHQ-DLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDL 128
T KL + + ++ DL + + ++ Y +++ GL HS V++RDL
Sbjct: 347 FQTPEKLCFILDLMNGGDLHYHLSQHGV--FTEKEVRFYAAEVMLGLEHMHSRFVVYRDL 174
Query: 129 KPQNLLINTEGAIKLADFGLARAF 152
KP N+L++ G ++++D GLA F
Sbjct: 173 KPANILLDENGHVRISDLGLACDF 102
>31489
Length = 329
Score = 53.1 bits (126), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 31/91 (34%), Positives = 52/91 (57%), Gaps = 8/91 (8%)
Frame = +3
Query: 52 ISLLKELNHPNIVKLLDVI------HTENKLYLVFEFLHQDLKKFMDASALTGIPL--PL 103
I +LK H NI+ + +++ H +++VF+ + DL + + + PL
Sbjct: 3 IKILKHFKHDNIISIREILKPKDSYHDFKDIHVVFDLMESDLHRIIYSDQ----PLTEEH 170
Query: 104 IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLL 134
I+ +L+Q+L+GL + HS V+HRDLKP NLL
Sbjct: 171 IRYFLYQILRGLKYIHSANVVHRDLKPSNLL 263
>14116
Length = 1017
Score = 52.4 bits (124), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 43/172 (25%), Positives = 88/172 (51%), Gaps = 9/172 (5%)
Frame = -1
Query: 8 EKIGEGTYGVVYKARNKL---TGEV-VALKKIRLDTETEGVPSTAIREISLLKELNHPNI 63
E+IG+G +G V + L G++ VA+K + + E + ++E ++K+ +H N+
Sbjct: 618 EEIGKGNFGCVKRGFLTLPEQKGDILVAVKTLHNNNPREIELQSFLQEALIMKDFHHSNV 439
Query: 64 VKLLDV-IHTENKLYLVFEFL-HQDLKKFMDASALTGIPLPLIKS---YLFQLLQGLAFC 118
+ L+ + ++ ++ +V F+ H DL ++ P IK Y + +G+ +
Sbjct: 438 LTLIGICLNLDDMPLVVLPFMKHGDLLTYIRDDQHQ----PTIKDLIMYGVDIARGMDYL 271
Query: 119 HSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVTRRALFP 170
+ +HRDL +N +++ + +K+ADFGLAR + + Y ++A P
Sbjct: 270 AGLKFVHRDLAARNCMLDEDFHVKVADFGLAR--DIYEKEYYSSENKKAKLP 121
>26009
Length = 886
Score = 38.9 bits (89), Expect(2) = 2e-07, Method: Compositional matrix adjust.
Identities = 17/33 (51%), Positives = 25/33 (75%)
Frame = +3
Query: 105 KSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINT 137
KS + QL+ L F HS +++HRD+KP+N+LI T
Sbjct: 720 KSVMKQLVSALDFMHSKQLVHRDIKPENVLILT 818
Score = 33.1 bits (74), Expect(2) = 2e-07, Method: Compositional matrix adjust.
Identities = 30/97 (30%), Positives = 42/97 (43%), Gaps = 5/97 (5%)
Frame = +2
Query: 2 ENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELN-- 59
E++ +++G GTYG V AR + TG VALK + T +RE +L+
Sbjct: 416 EHYDVCKELGRGTYGKVVLARCRHTGTQVALKLL-------PKSCTKLREFQREFQLSYF 574
Query: 60 ---HPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDA 93
H NI+ +V Y VF H L DA
Sbjct: 575 LSPHANIIDTYNVAFQTRSSY-VFAQEHAVLGDLFDA 682
>11404
Length = 563
Score = 52.0 bits (123), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 41/134 (30%), Positives = 67/134 (50%), Gaps = 8/134 (5%)
Frame = +1
Query: 10 IGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPN------I 63
IG+G++G V KA + E VA+K I+ + + A E+ LL+ +N + I
Sbjct: 163 IGKGSFGQVVKAYDHTDNEQVAIKIIK---NKKPFLNQAQIEVKLLEMMNRHDTDNKYYI 333
Query: 64 VKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHS--H 121
V+L + L LVFE L +L + + G+ L L + + QL L F +
Sbjct: 334 VRLKRHFMFRSHLCLVFELLSYNLYDLLRNTNFRGVSLNLTRKFAQQLCTALLFLATPEM 513
Query: 122 RVLHRDLKPQNLLI 135
++H DLKP+N+L+
Sbjct: 514 SIIHCDLKPENILL 555
>22005
Length = 873
Score = 51.6 bits (122), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 36/108 (33%), Positives = 56/108 (51%), Gaps = 11/108 (10%)
Frame = +1
Query: 10 IGEGTYGVVYKAR----NKLTGEVVALK------KIRLDTETEGVPSTAIREISLLKELN 59
IG+G +G V K + L GE++ K K+ + +E + S RE SL+ + +
Sbjct: 7 IGQGAFGRVSKLKFLGLASLVGELIPEKRP*LL*KMLKEDASEDLQSDFEREASLMADFD 186
Query: 60 HPNIVKLLDVIHTENKLYLVFEFLHQ-DLKKFMDASALTGIPLPLIKS 106
HPNIVKLL V + L+FEF+ + DL F+ + LP+ +S
Sbjct: 187 HPNIVKLLGVCAIGKPMCLLFEFMSKGDLNDFLRLCSPENYNLPVSRS 330
>18484
Length = 635
Score = 50.4 bits (119), Expect = 8e-07, Method: Compositional matrix adjust.
Identities = 38/136 (27%), Positives = 57/136 (41%), Gaps = 5/136 (3%)
Frame = +1
Query: 102 PLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTH 161
P+ Y ++ GL F H +++RDLK N+++++EG IK+ADFG+ + T
Sbjct: 43 PVAAFYAAEIAVGLFFLHDQGIIYRDLKLDNVMLDSEGHIKIADFGMCK------EGMTG 204
Query: 162 EVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQ----DFSKV 217
+ T R GTPD + P + Y S WA +
Sbjct: 205 DATTRTF----------------CGTPDYIA-PEIVLYQPYSKSVDWWAYGVLLFEMLAG 333
Query: 218 VPPLD-EDGRSLLSQM 232
PP D ED L S +
Sbjct: 334 QPPFDGEDEDELFSSI 381
>05084
Length = 1324
Score = 49.7 bits (117), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 34/97 (35%), Positives = 48/97 (49%), Gaps = 3/97 (3%)
Frame = +2
Query: 169 FPGDSEIDQLFRIFRTLGTPDEVVWPGVTSM-PDYKP-SFPKWARQDFSKVVPP-LDEDG 225
PGDS +DQL I + LGTP + M P+Y FP+ ++KV P +
Sbjct: 2 LPGDSGVDQLVEIIKVLGTPTRE---QIREMNPNYSEFKFPQIKAHPWTKVFRPRTPPEA 172
Query: 226 RSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHL 262
L+S++L Y P+ RI A AH FF ++ P L
Sbjct: 173 IQLVSRLLEYTPSARIQPMEACAHAFFDELRDPASRL 283
>29360
Length = 363
Score = 48.9 bits (115), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 37/124 (29%), Positives = 61/124 (49%), Gaps = 8/124 (6%)
Frame = +3
Query: 20 KARNKLTGEVVALKKIRLDTETEGVPSTAIR---EISLLKELNHP-----NIVKLLDVIH 71
K K T E+VA+K ++ PS A + E+S+L+ L+ N V+ +
Sbjct: 6 KCWKKGTSEIVAIKILK------NHPSYARQGQIEVSILQRLSQESADDYNFVRAFECFQ 167
Query: 72 TENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQ 131
+N LVFE L Q+L F+ + +PL I+ Q+L L ++H DLKP+
Sbjct: 168 HKNHTCLVFEMLEQNLYDFLKQNKFQPLPLKYIRPITQQVLTALRKLKQLGLIHADLKPE 347
Query: 132 NLLI 135
N+++
Sbjct: 348 NIML 359
>07940
Length = 1336
Score = 47.8 bits (112), Expect = 5e-06, Method: Compositional matrix adjust.
Identities = 19/45 (42%), Positives = 31/45 (68%)
Frame = -3
Query: 106 SYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLAR 150
SY +Q+ +G+ + S + +HRDL +N+L+ E +K+ADFGL R
Sbjct: 335 SYAYQVARGMEYLASKQCIHRDLAARNVLVAEEYVLKIADFGLTR 201
>21079
Length = 878
Score = 47.0 bits (110), Expect = 8e-06, Method: Compositional matrix adjust.
Identities = 30/98 (30%), Positives = 49/98 (50%), Gaps = 5/98 (5%)
Frame = +1
Query: 60 HPNIVKLLDVIHTENKLYLVFEFLHQDL---KKFMDASALTGIPLPLIKSYLFQLLQGLA 116
HP ++ L D + LV EF+ + D LT ++ Q+ G+
Sbjct: 1 HPKLLMLWDAFEAPRTMVLVMEFVGAGELFERVIRDDFVLTERDC---VHFVRQICSGVG 171
Query: 117 FCHSHRVLHRDLKPQNLLINTEGA--IKLADFGLARAF 152
+ H+ +LH DLKP+N+L ++ + IK+ DFGLAR +
Sbjct: 172 YMHTQSILHLDLKPENVLCVSDNSNQIKIIDFGLARFY 285
>21800
Length = 855
Score = 47.0 bits (110), Expect = 8e-06, Method: Compositional matrix adjust.
Identities = 34/105 (32%), Positives = 56/105 (53%), Gaps = 13/105 (12%)
Frame = +2
Query: 47 TAIREISLLKELNHPN--------IVKLLDVIHTE----NKLYLVFEFLHQDLKKFMDAS 94
TA+ EI LLK + + + V+LLD + +VFE L +L K + S
Sbjct: 431 TALDEIKLLKCVRNSDETDPAREKSVQLLDDFKISGVNGTHVCMVFEVLGYNLLKLIIRS 610
Query: 95 ALTGIPLPLIKSYLFQLLQGLAFCHSH-RVLHRDLKPQNLLINTE 138
GIP+ +K + Q+L+GL + H+ ++H D+KP+N+LI +
Sbjct: 611 NYQGIPVHNVKLIIRQVLEGLNYLHAKCNIIHTDIKPENILICVD 745
>16708
Length = 1397
Score = 47.0 bits (110), Expect = 9e-06, Method: Compositional matrix adjust.
Identities = 42/161 (26%), Positives = 64/161 (39%), Gaps = 21/161 (13%)
Frame = -1
Query: 103 LIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGV---PVRTY 159
++ Q + L H V+H D+K N+L++ G KL D+G+A+ + V P T+
Sbjct: 1091 MVCCIAGQXVCALEHIHELGVVHMDVKADNVLVDAHGNCKLTDYGIAQLYKVYPAPTETH 912
Query: 160 THEVTRRALF----------------PGDSEIDQLFRIFRTLGTPDEVVWPGV-TSMPDY 202
+ T + F GD FR+ + L T V V S P
Sbjct: 911 SSGCTNKRTFYTRPPATMTPSERFSEEGDGIGTDYFRLGQMLWTLTGAVLLHVWVSRP-- 738
Query: 203 KPSFPKWARQDFSKVVPPLDEDGRS-LLSQMLHYDPNKRIS 242
P P W R P + G S + ++ H DPN R+
Sbjct: 737 -PKLPDWCR------TPESELSGMSDFIEKLCHGDPNMRLG 636
>11185
Length = 473
Score = 46.6 bits (109), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 20/50 (40%), Positives = 32/50 (64%)
Frame = +1
Query: 104 IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFG 153
I+ + L+ GL + HS +L DL+P +L++T G +K ADFGL++ G
Sbjct: 7 IRDFGIHLVTGLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEG 156
>13212
Length = 1067
Score = 46.2 bits (108), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 49/166 (29%), Positives = 72/166 (43%), Gaps = 19/166 (11%)
Frame = -1
Query: 110 QLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVTRRALF 169
++ L F H H V+HRD+K N+L+ +G +KLADFG++ T T + +R F
Sbjct: 956 EMCMALDFLHRHHVIHRDIKAGNVLLTIDGEVKLADFGVSAK-----NTQTQQ--KRDTF 798
Query: 170 PGDS-EIDQLFRIFRTL-GTPDEV---VWP-GVTSM------PDYKPSFPKWARQDFSKV 217
G + + TL TP + +W GVT + P K P K
Sbjct: 797 IGTPYWMAPEVVLCETLKDTPYDFKADIWSLGVTLIEFAQIEPPNKEMHPMRVLIKIHKS 618
Query: 218 VPPLDEDGR-------SLLSQMLHYDPNKRISAKAALAHPFFQDVT 256
PP E + +++ L DPN R +A L HPF + T
Sbjct: 617 DPPTLEKPKKWTKLFKDFIAKCLVKDPNLRPTAAELLEHPFMKRAT 480
>28157
Length = 400
Score = 44.7 bits (104), Expect = 4e-05, Method: Compositional matrix adjust.
Identities = 40/130 (30%), Positives = 64/130 (49%), Gaps = 10/130 (7%)
Frame = +3
Query: 30 VALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQ-DLK 88
VA+K+I E+E + ++E+ L ++HPNIV L ++ + LV E+ L
Sbjct: 9 VAVKRI----ESEQEKKSFMQELKQLSRVSHPNIVCLYGAC-RDHPVCLVMEYAEGGSLY 173
Query: 89 KFMDASALTGIPLPLIKS-----YLFQLLQGLAFCHSHR---VLHRDLKPQNLLINTEGA 140
+ S P P + +L Q G+ + H + ++HRDLKP NLL+ G
Sbjct: 174 NVLHGSG----PQPQYTAAHAMNWLLQCALGVEYLHGMKPKALIHRDLKPPNLLLIQCGT 341
Query: 141 -IKLADFGLA 149
+K+ DFG A
Sbjct: 342 KLKICDFGTA 371
>26560
Length = 398
Score = 44.3 bits (103), Expect = 5e-05, Method: Compositional matrix adjust.
Identities = 19/49 (38%), Positives = 33/49 (67%)
Frame = -1
Query: 104 IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAF 152
++ Y +++ GL HS V++RDLKP N+L++ G ++++D GLA F
Sbjct: 350 VRFYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGLACDF 204
>26909
Length = 394
Score = 43.9 bits (102), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 28/94 (29%), Positives = 45/94 (47%), Gaps = 9/94 (9%)
Frame = +2
Query: 176 DQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDF---------SKVVPPLDEDGR 226
DQL RIF +G P E W + MP+++ + R + K D
Sbjct: 83 DQLDRIFNVMGFPQEKDWEDIRRMPEHQQLTKDFKRSSYVNCNLMKYMEKHKVKADSKAF 262
Query: 227 SLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP 260
LL ++L DP KRI+++ A+ P+F + +P+P
Sbjct: 263 HLLQKLLTMDPVKRITSEQAMKDPYF--LEEPLP 358
>31789
Length = 676
Score = 43.1 bits (100), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 33/113 (29%), Positives = 53/113 (46%), Gaps = 6/113 (5%)
Frame = +2
Query: 9 KIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLD 68
+IG G++ VYK + G VA +++ + E +LKEL HPNIV+ D
Sbjct: 341 EIGRGSFKTVYKGLDTELGVAVAWCELQDKKWNKTERQRFKEEAEMLKELQHPNIVRFFD 520
Query: 69 VIHTENK-----LYLVFEFLHQD-LKKFMDASALTGIPLPLIKSYLFQLLQGL 115
N + LV E + LK ++ I L ++K++ Q+L+GL
Sbjct: 521 YWEEHNHRNRKVIILVTELMTSGTLKTYL--KRFKKINLKVLKNWCRQILKGL 673
>26711
Length = 405
Score = 42.4 bits (98), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 23/57 (40%), Positives = 34/57 (59%), Gaps = 2/57 (3%)
Frame = -2
Query: 110 QLLQGLAFCHSHRVLHRDLKPQNLLINTE--GAIKLADFGLARAFGVPVRTYTHEVT 164
Q+L L H+ V+H DLKP NLL++ + +++L DFGLAR P T+ + T
Sbjct: 392 QVLDILQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARKLYPPQETFLNHGT 222
>00715
Length = 1788
Score = 42.4 bits (98), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 28/103 (27%), Positives = 49/103 (47%), Gaps = 11/103 (10%)
Frame = +1
Query: 58 LNHPNIVKLLDVIHT---ENKLYLVFEFLH--------QDLKKFMDASALTGIPLPLIKS 106
L H N+V +L E+ +L E++ D ++ +D+S + L
Sbjct: 97 LRHVNVVSILGATSLHRFEDGAWLAMEYVGPLNLQTILNDHQQDIDSSMRLSLAL----- 261
Query: 107 YLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLA 149
Q+ +GL + HS ++H DLKP N L+ + +++ADFG
Sbjct: 262 ---QMARGLHYLHSINIVHLDLKPANCLLTRDLKLRIADFGCC 381
>00638
Length = 1595
Score = 42.0 bits (97), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 16/33 (48%), Positives = 25/33 (75%)
Frame = +2
Query: 104 IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLIN 136
I+ YL++L++ L FCHS ++HRD+KP L+N
Sbjct: 422 IRFYLYELMKALDFCHSMGIMHRDVKPSPPLVN 520
>12786
Length = 460
Score = 42.0 bits (97), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 20/52 (38%), Positives = 32/52 (61%)
Frame = -3
Query: 98 GIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLA 149
G+ +IK Y ++L+ + H+ V+H DLKP N ++ G +KL DFG+A
Sbjct: 422 GLDRMMIKFYWREMLRAVKALHNEGVIHSDLKPANFML-VAGNLKLIDFGIA 270
>18287
Length = 678
Score = 39.7 bits (91), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 32/113 (28%), Positives = 48/113 (42%), Gaps = 15/113 (13%)
Frame = -3
Query: 163 VTRRALFPGDSEIDQLFRIFRTLGTPD----EVVWPGVTSMPDYKPSFPKWARQDFSKVV 218
++RR LF + QL I +GTP E G + +P F + +
Sbjct: 622 LSRRILFQAQGPVQQLDMIINLVGTPRPEDMERACEGARNHILNQP-FRRQNLLTLYNLS 446
Query: 219 PPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQD-----------VTKPVP 260
P + LL++ML +P RISA+ AL+HP+ + KPVP
Sbjct: 445 PHATHEAVRLLTRMLILNPKNRISAEEALSHPYLDEGRVRFHSCMCSCCKPVP 287
>15549
Length = 470
Score = 39.3 bits (90), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 14/40 (35%), Positives = 30/40 (75%)
Frame = -1
Query: 2 ENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTET 41
+ F+ +E++G+G YG+V++A+NK+ + A+K+I L ++
Sbjct: 218 DEFECIEQMGKGGYGIVFRAKNKVDEQEYAVKRIALPSDA 99
>28638
Length = 1458
Score = 38.9 bits (89), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 23/71 (32%), Positives = 35/71 (49%), Gaps = 4/71 (5%)
Frame = -1
Query: 96 LTGIPLPLIKSYLFQLLQGLAFCHS--HRVLHRDLKPQNLLINT--EGAIKLADFGLARA 151
L G+ L L + + QL L F + ++H DLKP+N+L+ AIK+ DFG +
Sbjct: 855 LEGVSLNLTRKFAQQLCTALLFLATPEMNIIHCDLKPENILLCNPKRSAIKIVDFGSSCQ 676
Query: 152 FGVPVRTYTHE 162
G + Y
Sbjct: 675 LGQRIYQYIQS 643
Score = 29.3 bits (64), Expect = 1.7, Method: Compositional matrix adjust.
Identities = 13/31 (41%), Positives = 19/31 (61%)
Frame = -2
Query: 226 RSLLSQMLHYDPNKRISAKAALAHPFFQDVT 256
+ L+ +ML +DP RIS AL H FF+ +
Sbjct: 260 KDLILRMLDFDPKTRISPYYALQHNFFRKTS 168
>00394
Length = 548
Score = 38.9 bits (89), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 21/66 (31%), Positives = 31/66 (46%)
Frame = -2
Query: 9 KIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLD 68
+IG G++ VYK + G VA +++ + E +LKEL HPNIV+ D
Sbjct: 277 EIGRGSFKTVYKGLDTELGVAVAWCELQDKKWNKAERQRFKEEAEMLKELQHPNIVRFFD 98
Query: 69 VIHTEN 74
N
Sbjct: 97 YWEEHN 80
>06358
Length = 1517
Score = 38.5 bits (88), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 38/162 (23%), Positives = 72/162 (44%), Gaps = 19/162 (11%)
Frame = +3
Query: 4 FQKVEKIGEGTYGVVYKARNKLTGE---VVALKKIRLDT----ETEGVPSTAIREISLLK 56
+ +V G G V+ A K T E V +K +D + E + + L
Sbjct: 12 YNQVASAGPGLLWKVFAASKKSTKEEASVFVFEKKSVDRYSRRDREAIVEVLRVGVQQLT 191
Query: 57 ELNHPNIVKLLDVIH-TENKLYLVFEFLHQDLKKFM-DASALTGIPLPL---------IK 105
+L HP I+ +++ + + L E + L + D S++ +P L IK
Sbjct: 192 KLRHPKILAVINPLEESRETLAFATEPVFASLANVLGDLSSIXTVPKELQDYQLYDVEIK 371
Query: 106 SYLFQLLQGLAFCHSH-RVLHRDLKPQNLLINTEGAIKLADF 146
L Q+ + L F H+ +++HR++ P+ +++ G+ KLA +
Sbjct: 372 HGLLQVTEALGFLHNDAKMMHRNVCPEAIMLTKLGSWKLAGY 497
>07291
Length = 833
Score = 38.5 bits (88), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 15/53 (28%), Positives = 32/53 (60%)
Frame = +1
Query: 110 QLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHE 162
Q+ G+A+ +V+HR+L +N ++ +G ++L+D+G+ + P YT +
Sbjct: 73 QIADGMAYLQEVKVVHRNLAARNCIVTEDGRLQLSDYGVTGSL-FPQSYYTAD 228
>07836
Length = 1478
Score = 35.8 bits (81), Expect = 0.020, Method: Compositional matrix adjust.
Identities = 33/134 (24%), Positives = 61/134 (45%), Gaps = 11/134 (8%)
Frame = -1
Query: 27 GEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLL--DVIHTEN--KLYLVFEF 82
GE VA+K E T + + LL+ H NI+ + D+ T + +L+L+ ++
Sbjct: 1478 GENVAVKIFFTTEEASWFRETELYQTVLLR---HENILGFIAADIKGTGSWTQLFLITDY 1308
Query: 83 LHQD-------LKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI 135
H++ L + +D+S + + I ++ + HRD+K +N+L+
Sbjct: 1307 -HENGSLHDYLLSRVLDSSEMLALAHSAICGLAHLHIEIFGTRGKPAIAHRDIKSKNILV 1131
Query: 136 NTEGAIKLADFGLA 149
G +AD GLA
Sbjct: 1130 KKNGTCCIADLGLA 1089
>17300
Length = 480
Score = 35.0 bits (79), Expect = 0.031, Method: Compositional matrix adjust.
Identities = 15/38 (39%), Positives = 22/38 (57%)
Frame = +1
Query: 113 QGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLAR 150
G+ +HRDL +N+L+N K+ADFGL+R
Sbjct: 7 SGMGXLADMGYVHRDLAARNILVNEILVCKVADFGLSR 120
>20640
Length = 1492
Score = 35.0 bits (79), Expect = 0.035, Method: Compositional matrix adjust.
Identities = 13/28 (46%), Positives = 21/28 (75%)
Frame = +1
Query: 124 LHRDLKPQNLLINTEGAIKLADFGLARA 151
+HRDL +N L+ + +K++DFGLAR+
Sbjct: 10 VHRDLATRNCLVGHDLVVKISDFGLARS 93
>01392
Length = 1806
Score = 34.3 bits (77), Expect = 0.057, Method: Compositional matrix adjust.
Identities = 17/48 (35%), Positives = 26/48 (54%), Gaps = 3/48 (6%)
Frame = -1
Query: 110 QLLQGLAFCHSHRVLHRDLKPQNLL---INTEGAIKLADFGLARAFGV 154
+ + L F HS + HRDLKP+N+L ++ +K+ DF LA
Sbjct: 1767 HIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGISC 1624
>18481
Length = 437
Score = 33.9 bits (76), Expect = 0.063, Method: Compositional matrix adjust.
Identities = 18/46 (39%), Positives = 25/46 (54%), Gaps = 3/46 (6%)
Frame = -1
Query: 110 QLLQGLAFCHSHRVLHRDLKPQNLLINTE---GAIKLADFGLARAF 152
QLL L F H +HRDLKP N L+ + + DFGL++ +
Sbjct: 173 QLLSRLEFIHQKCFIHRDLKPDNFLMGLGRHCHRLYIIDFGLSKRY 36
>35032
Length = 465
Score = 33.5 bits (75), Expect = 0.082, Method: Compositional matrix adjust.
Identities = 13/25 (52%), Positives = 20/25 (80%)
Frame = +3
Query: 228 LLSQMLHYDPNKRISAKAALAHPFF 252
L+ ++L+YDP+KR++ ALAHPF
Sbjct: 150 LVKRLLNYDPSKRLTPXXALAHPFL 224
>17806
Length = 433
Score = 32.7 bits (73), Expect = 0.17, Method: Compositional matrix adjust.
Identities = 31/124 (25%), Positives = 56/124 (45%), Gaps = 9/124 (7%)
Frame = +1
Query: 7 VEKIGEGTYGVVYKARNKLTGEVVALKKIRL----DTETEGVPSTAIREISLLKELNHPN 62
++++G G +G V ++ + V+ K+ + D T+ E++ +EL+HPN
Sbjct: 64 LKELGTGWFGKVIESDAERITTGVSRSKVVVKMLKDDATKDEQLLFFEEVAPFRELDHPN 243
Query: 63 IVKLLDVIHTENKLYLVFEF-----LHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAF 117
IV+LL N + ++ E L Q L+ A+ L+K + + GLA
Sbjct: 244 IVRLLGQCTEMNPMLMLMECAALGNLKQYLRNHRHQQAMLIQKNRLLK-FAMDISSGLAC 420
Query: 118 CHSH 121
H H
Sbjct: 421 LHGH 432
>12672
Length = 773
Score = 30.8 bits (68), Expect = 0.55, Method: Compositional matrix adjust.
Identities = 11/34 (32%), Positives = 22/34 (64%)
Frame = +3
Query: 113 QGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADF 146
G+ + + + +HRD+K N+L+++E K+ DF
Sbjct: 24 SGIQYLNDNGHVHRDIKTANILLDSEYTAKVGDF 125
>17644
Length = 463
Score = 30.4 bits (67), Expect = 0.70, Method: Compositional matrix adjust.
Identities = 11/24 (45%), Positives = 19/24 (79%)
Frame = +3
Query: 228 LLSQMLHYDPNKRISAKAALAHPF 251
L+ ++L YDP++R++ AL+HPF
Sbjct: 90 LVQRLLTYDPSQRLTPDLALSHPF 161
>20773
Length = 391
Score = 30.4 bits (67), Expect = 0.86, Method: Compositional matrix adjust.
Identities = 11/25 (44%), Positives = 20/25 (80%)
Frame = -1
Query: 227 SLLSQMLHYDPNKRISAKAALAHPF 251
+L+ ++L YDP++R++ AL+HPF
Sbjct: 304 NLVQRLLTYDPSQRLTPDLALSHPF 230
>15931
Length = 447
Score = 29.3 bits (64), Expect = 1.9, Method: Compositional matrix adjust.
Identities = 15/40 (37%), Positives = 24/40 (60%), Gaps = 3/40 (7%)
Frame = +1
Query: 217 VVPPLDEDGRSL---LSQMLHYDPNKRISAKAALAHPFFQ 253
V P +ED + L + +ML Y+ + R S + A+ HPFF+
Sbjct: 40 VKDPDNEDHQQLFDLMDKMLSYEVSTRYSLRQAMRHPFFR 159
>16350
Length = 1108
Score = 28.5 bits (62), Expect = 3.0, Method: Compositional matrix adjust.
Identities = 10/27 (37%), Positives = 17/27 (62%)
Frame = +3
Query: 227 SLLSQMLHYDPNKRISAKAALAHPFFQ 253
L+ ML +DP +R +A +L HP+ +
Sbjct: 762 DFLAPMLEFDPEQRATAAQSLQHPWLK 842
>20513
Length = 405
Score = 28.5 bits (62), Expect = 3.2, Method: Compositional matrix adjust.
Identities = 12/34 (35%), Positives = 19/34 (55%)
Frame = -1
Query: 227 SLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP 260
L+ ML +DP +R +A +L HP+ + P P
Sbjct: 282 DFLAPMLEFDPEQRATAAQSLQHPWLKLDA*PEP 181
>13078
Length = 773
Score = 28.1 bits (61), Expect = 3.6, Method: Compositional matrix adjust.
Identities = 14/39 (35%), Positives = 24/39 (61%), Gaps = 3/39 (7%)
Frame = -1
Query: 220 PLDEDGRSL---LSQMLHYDPNKRISAKAALAHPFFQDV 255
P +ED + L + +ML Y+ + R S + A+ HPFF+ +
Sbjct: 485 PDNEDHQQLFDLMDKMLSYEVSTRYSLRQAMRHPFFRKL 369
>26565
Length = 497
Score = 27.7 bits (60), Expect = 4.6, Method: Compositional matrix adjust.
Identities = 16/32 (50%), Positives = 19/32 (59%)
Frame = +3
Query: 58 LNHPNIVKLLDVIHTENKLYLVFEFLHQDLKK 89
L+HPN V L IHT +K Y + LH LKK
Sbjct: 339 LHHPNNVSFLFYIHTISKYYFMH*HLHFKLKK 434
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000272233 | hsapiens_gene_ensembl | Rho-related
GTP-binding protein RhoB precursor (H6).
[Source:Uniprot/SWISSPROT;Acc:P62745]
(196 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
19006 262 6e-71
10708 151 2e-61
11728 201 2e-52
19656 158 1e-39
31291 139 1e-33
17872 122 8e-29
34468 70 8e-13
07580 69 1e-12
08428 65 1e-11
26083 65 2e-11
14456 62 2e-10
00858 62 2e-10
17511 62 2e-10
07465 60 4e-10
11257 60 5e-10
09700 59 1e-09
01972 50 2e-09
27191 58 2e-09
33374 55 1e-08
13750 53 9e-08
34359 49 9e-07
26536 49 1e-06
35581 48 3e-06
33380 47 4e-06
33794 47 5e-06
13901 47 7e-06
00552 44 5e-05
05468 43 9e-05
32770 42 1e-04
28321 37 0.006
08153 36 0.009
09827 35 0.015
14775 34 0.035
29380 34 0.035
14119 34 0.037
18509 33 0.060
36757 33 0.092
36482 33 0.097
06994 32 0.16
25618 31 0.32
13745 30 0.76
12443 29 1.1
12339 28 1.6
19819 27 5.2
04861 27 6.4
>19006
Length = 568
Score = 262 bits (670), Expect = 6e-71, Method: Compositional matrix adjust.
Identities = 125/146 (85%), Positives = 135/146 (92%)
Frame = -2
Query: 5 RKKLVVVGDGACGKTCLLIVFSKDEFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQE 64
++KLV+VGDGACGKTCLLIVFSKD+FPEVYVPTVFENYVADIEVD KQVELALWDTAGQE
Sbjct: 438 KEKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDSKQVELALWDTAGQE 259
Query: 65 DYDRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWVPEVKHFCPNVPIILVANKKDLRSD 124
DYDRLRPLSYPDTDVILMCFS+DSPDSLENIPEKW PEV+HFCPNVPIILV NKKDLR+D
Sbjct: 258 DYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVRHFCPNVPIILVGNKKDLRND 79
Query: 125 EHVRTELARMKQEPVRTDDGRAMAVR 150
E+ + EL +MKQEPVR D RA VR
Sbjct: 78 ENTKRELMKMKQEPVRL-DRRARHVR 4
>10708
Length = 2775
Score = 151 bits (382), Expect(2) = 2e-61, Method: Compositional matrix adjust.
Identities = 69/94 (73%), Positives = 80/94 (85%)
Frame = -3
Query: 97 EKWVPEVKHFCPNVPIILVANKKDLRSDEHVRTELARMKQEPVRTDDGRAMAVRIQAYDY 156
+KW PEV+HFCPNVPIILV NKKDLR+DE+ + EL +MKQEPVR D+GRAM+ +I AY Y
Sbjct: 2590 KKWTPEVRHFCPNVPIILVGNKKDLRNDENTKRELMKMKQEPVRLDEGRAMSEKINAYSY 2411
Query: 157 LECSAKTKEGVREVFETATRAALQKRYGSQNGCI 190
LECSAKTKEGVREVFETATRAALQ + + GCI
Sbjct: 2410 LECSAKTKEGVREVFETATRAALQTKKKKKGGCI 2309
Score = 100 bits (250), Expect(2) = 2e-61, Method: Compositional matrix adjust.
Identities = 46/48 (95%), Positives = 48/48 (100%)
Frame = -2
Query: 51 KQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSVDSPDSLENIPEK 98
+QVELALWDTAGQEDYDRLRPLSYPDTDVILMCFS+DSPDSLENIPEK
Sbjct: 2729 QQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEK 2586
>11728
Length = 635
Score = 201 bits (511), Expect = 2e-52, Method: Compositional matrix adjust.
Identities = 99/167 (59%), Positives = 116/167 (69%)
Frame = -1
Query: 1 MAAIRKKLVVVGDGACGKTCLLIVFSKDEFPEVYVPTVFENYVADIEVDGKQVELALWDT 60
M AI K VVVGDGA GKTCLLI ++ + FP Y+PTVF+NY A++ VD K + L LWDT
Sbjct: 497 MQAI--KCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPINLGLWDT 324
Query: 61 AGQEDYDRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWVPEVKHFCPNVPIILVANKKD 120
AGQEDYDRLRPLSYP TDV L+CFS+ SP S EN+ KW PEV H CPN PIILV K D
Sbjct: 323 AGQEDYDRLRPLSYPQTDVFLICFSLISPASFENVKAKWYPEVSHHCPNTPIILVGTKLD 144
Query: 121 LRSDEHVRTELARMKQEPVRTDDGRAMAVRIQAYDYLECSAKTKEGV 167
LR D+ +L K P+ G AMA I A YLECSA T++G+
Sbjct: 143 LREDKETIEKLKEKKLAPITYPQGLAMAKDIGAGKYLECSALTQKGL 3
>19656
Length = 428
Score = 158 bits (399), Expect = 1e-39, Method: Compositional matrix adjust.
Identities = 73/109 (66%), Positives = 82/109 (75%)
Frame = +3
Query: 1 MAAIRKKLVVVGDGACGKTCLLIVFSKDEFPEVYVPTVFENYVADIEVDGKQVELALWDT 60
MA K VVVGDGA GKTCLLI ++ + FP Y+PTVF+NY A++ VDG+ V L LWDT
Sbjct: 99 MAMQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGRPVNLGLWDT 278
Query: 61 AGQEDYDRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWVPEVKHFCPN 109
AGQEDYDRLRPLSYP TDV L+CFSV SP S ENI KW PEV H CP
Sbjct: 279 AGQEDYDRLRPLSYPQTDVFLLCFSVASPASFENIRAKWYPEVNHHCPG 425
>31291
Length = 446
Score = 139 bits (349), Expect = 1e-33, Method: Compositional matrix adjust.
Identities = 63/125 (50%), Positives = 87/125 (69%)
Frame = -1
Query: 55 LALWDTAGQEDYDRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWVPEVKHFCPNVPIIL 114
L LWDTAGQEDYDRLRPL+YP+TDV ++ FS+ S S++N+ KW PE++H P+VPI+L
Sbjct: 446 LQLWDTAGQEDYDRLRPLAYPNTDVFMLXFSLMSEASMKNVKVKWYPEIRHHDPHVPIVL 267
Query: 115 VANKKDLRSDEHVRTELARMKQEPVRTDDGRAMAVRIQAYDYLECSAKTKEGVREVFETA 174
V K DLR D+ +L +Q+PV ++ G +A I+A Y ECS+KT+E ++ FE
Sbjct: 266 VGTKLDLRQDKEAVRKLRSSRQDPVSSNQGNDLAKAIKAKRYFECSSKTQENLKTAFEET 87
Query: 175 TRAAL 179
R AL
Sbjct: 86 VRVAL 72
>17872
Length = 700
Score = 122 bits (306), Expect = 8e-29, Method: Compositional matrix adjust.
Identities = 56/118 (47%), Positives = 84/118 (71%)
Frame = -1
Query: 63 QEDYDRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWVPEVKHFCPNVPIILVANKKDLR 122
Q+D+D LRPL YP+T+V L+CFSV SP S N+ EKWVPE+++ CP P+++V + DLR
Sbjct: 700 QDDFDSLRPLCYPETNVFLLCFSVVSPTSFHNVMEKWVPELRYHCPGAPLVVVGTQSDLR 521
Query: 123 SDEHVRTELARMKQEPVRTDDGRAMAVRIQAYDYLECSAKTKEGVREVFETATRAALQ 180
+D V ELA+ K++PV ++ MA ++ A Y+ECSA T++ ++EVF+T A+L
Sbjct: 520 NDVKVLIELAKYKEKPVSEEEAVKMADQLGA-QYVECSALTQKNLKEVFDTGILASLN 350
>34468
Length = 1502
Score = 69.7 bits (169), Expect = 8e-13, Method: Compositional matrix adjust.
Identities = 43/131 (32%), Positives = 69/131 (52%), Gaps = 4/131 (3%)
Frame = +1
Query: 7 KLVVVGDGACGKTCLLIVFSKDEFPEVYVPTVFENYV-ADIEVDGKQVELALWDTAGQED 65
K++V+GD GKTCL F +FP+ T+ ++ I+VD + ++L LWDTAGQE
Sbjct: 499 KIIVIGDSNVGKTCLTYRFCLGKFPDKTEATIGVDFREKSIQVDSEHLKLQLWDTAGQER 678
Query: 66 YDR-LRPLSYPDTDVILMCFSVDSPDSLENIPEKWVPEV--KHFCPNVPIILVANKKDLR 122
+ + + Y + ++ + + S EN+P W+ E + +P ILV NK D+
Sbjct: 679 FRKSMVQHYYRNVHAVVFVYDMTKMSSFENMP-AWIEECDRHNLTKYIPRILVGNKCDVV 855
Query: 123 SDEHVRTELAR 133
V T LA+
Sbjct: 856 ERIAVNTNLAQ 888
>07580
Length = 921
Score = 68.9 bits (167), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 54/172 (31%), Positives = 84/172 (48%), Gaps = 5/172 (2%)
Frame = +3
Query: 30 FPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSVDSP 89
F E Y PT+ ++Y +EVDG+Q L + DTAG E + +R L + L+ +S+ +
Sbjct: 135 FVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFLLAYSITAQ 314
Query: 90 DSLENIPE--KWVPEVKHFCPNVPIILVANKKDLRSDEHVRTELARMKQEPVRTDDGRAM 147
+ ++ E + + VK +VP++LV NK DL DE V V D G+ +
Sbjct: 315 STFNDLQELREQILRVKD-TDDVPMLLVGNKCDL-EDERV-----------VGKDQGQGL 455
Query: 148 AVRIQAYDYLECSAKTKEGVREVFETATRAALQK---RYGSQNGCINCCKVL 196
A R + +LE SAK + V E+F R +K + G + C VL
Sbjct: 456 A-RSFSCAFLETSAKARINVNEIFMDLVRQINKKSPEQSGKRTKSKKSCTVL 608
>08428
Length = 1109
Score = 65.5 bits (158), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 46/172 (26%), Positives = 81/172 (47%), Gaps = 2/172 (1%)
Frame = -3
Query: 7 KLVVVGDGACGKTCLLIVFSKDEFPEVYVPTVFENYVA-DIEVDGKQVELALWDTAGQED 65
K+ ++GD GK+ +++ F + T+ ++++ + VDG +WDTAGQE
Sbjct: 1065 KVCLLGDSGVGKSSIVLRFVTGSYRPSQESTIGASFMSKSLVVDGAGYRFQIWDTAGQEK 886
Query: 66 YDRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWVPEVKHFC-PNVPIILVANKKDLRSD 124
+ L P+ Y ++ + V P + +++ + W+ E++ F PN+ + + NK DL
Sbjct: 885 FRALAPMYYRGAAAAVIVYDVTRPRTFKSV-KSWIQELRSFGPPNIVLAIAGNKCDL--- 718
Query: 125 EHVRTELARMKQEPVRTDDGRAMAVRIQAYDYLECSAKTKEGVREVFETATR 176
E +R V D + A I A + E SA T V E+F R
Sbjct: 717 EELRE---------VVEKDAQEYASSISAI-FGETSAMTAVNVEEMFTELAR 592
>26083
Length = 432
Score = 65.1 bits (157), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 38/118 (32%), Positives = 66/118 (55%), Gaps = 3/118 (2%)
Frame = +1
Query: 4 IRK-KLVVVGDGACGKTCLLIVFSKDEFPEVYVPTVFENYVA-DIEVDGKQVELALWDTA 61
+RK KLV +G+ + GKT L+ F D F Y T+ ++++ + ++ + + L LWDTA
Sbjct: 70 LRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTIRLQLWDTA 249
Query: 62 GQEDYDRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWVPEVK-HFCPNVPIILVANK 118
GQE + L P D+ V ++ + + + +S KW+ +V+ +V I+LV NK
Sbjct: 250 GQERFRSLIPSYIRDSSVAVVVYDITNANSFHQ-TSKWIDDVRTERGSDVIIMLVGNK 420
>14456
Length = 1867
Score = 62.0 bits (149), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 45/169 (26%), Positives = 71/169 (42%), Gaps = 6/169 (3%)
Frame = -1
Query: 14 GACGKTCLLIVFSKDEFPEVYVPTVFENYV-ADIEVDGKQVELALWDTAGQEDYDRLRPL 72
G GK+ L+ F ++F T+ ++ D+ VD + + +WDTAGQE + LR
Sbjct: 1114 GGVGKSSLMNRFVSNKFDAQSFHTIGVEFLNKDVVVDDETYTMQIWDTAGQERFKSLRTP 935
Query: 73 SYPDTDVILMCFSVDSPDSLENIPEKWVPEVKHFCP-----NVPIILVANKKDLRSDEHV 127
Y D L+ FSVDS S N+ W E ++ P +++ NK D+ +
Sbjct: 934 FYRGADCCLLTFSVDSMQSFRNLS-MWRKEFLYYADIQDGVTFPFVVLGNKIDVEGRQ-- 764
Query: 128 RTELARMKQEPVRTDDGRAMAVRIQAYDYLECSAKTKEGVREVFETATR 176
V ++ R+ Y E SAK V + F A +
Sbjct: 763 -----------VTNEEARSWCTANSNAPYFETSAKDATNVEKAFLAAVQ 650
>00858
Length = 1658
Score = 61.6 bits (148), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 48/163 (29%), Positives = 76/163 (46%), Gaps = 4/163 (2%)
Frame = -2
Query: 18 KTCLLIVFSKDEFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDT 77
K+ L I ++ F E Y PT ++ + +DG+ L + DTAGQE+ +R
Sbjct: 1552 KSALTIQLXQNHFVEEYDPTXEDSXRKQVVIDGETCLLDILDTAGQEEXSAMRDQCMRTG 1373
Query: 78 DVILMCFSVDSPDSLENIPEKWVPEVKHF--CPNVPIILVANKKDLRSDEHVRTELARMK 135
+ L F+V + S E+I ++ ++K VP++LV NK DL
Sbjct: 1372 EGFLCVFAVXNLKSFEDI-NQYREQIKRVKDADEVPMVLVGNKVDL-------------- 1238
Query: 136 QEPVRTDDGRAMAVRIQAYD--YLECSAKTKEGVREVFETATR 176
P+R + R + Y Y+E SAKT++GV + F T R
Sbjct: 1237 --PIRNVEQRQGKHMAELYHIPYVETSAKTRQGVDDAFYTLVR 1115
>17511
Length = 483
Score = 61.6 bits (148), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 38/130 (29%), Positives = 68/130 (52%), Gaps = 9/130 (6%)
Frame = -3
Query: 1 MAAIRK---KLVVVGDGACGKTCLLIVFSKDEFPEVYVPTVFENYVA-DIEVDGKQVELA 56
MA+ +K K++++GD GKT L+ + +F Y T+ +++ ++ VD + V +
Sbjct: 388 MASRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQ 209
Query: 57 LWDTAGQEDYDRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWVPE-VKHFCP----NVP 111
+WDTAGQE + L Y D ++ F V P++ ++ + W E + P N P
Sbjct: 208 IWDTAGQERFQSLGVAFYRGADCCVLVFDVTMPNTFRSL-DSWRDEFLIQASPRDPENFP 32
Query: 112 IILVANKKDL 121
+++ NK DL
Sbjct: 31 FVVIGNKIDL 2
>07465
Length = 1103
Score = 60.5 bits (145), Expect = 4e-10, Method: Compositional matrix adjust.
Identities = 48/149 (32%), Positives = 71/149 (47%), Gaps = 1/149 (0%)
Frame = +3
Query: 24 VFSKDEFPEVYVPTVFENYVA-DIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILM 82
+F+KD Y T+ +++ IEV G+ V L LWDTAGQE++D + Y ++
Sbjct: 270 IFTKD-----YKKTIGVDFLERQIEVGGEDVRLMLWDTAGQEEFDAITKAYYRGAQACVL 434
Query: 83 CFSVDSPDSLENIPEKWVPEVKHFCPNVPIILVANKKDLRSDEHVRTELARMKQEPVRTD 142
FS DS E + E W +V+ + +++V NK DL D VR E A
Sbjct: 435 AFSTVDRDSFEAL-ETWKRKVEDEVGEIGMVIVQNKIDLIDDAVVRPEEA---------- 581
Query: 143 DGRAMAVRIQAYDYLECSAKTKEGVREVF 171
+ A +R++ Y S K V EVF
Sbjct: 582 ENLAKKLRLRFY---RTSVKENMNVDEVF 659
>11257
Length = 1102
Score = 60.5 bits (145), Expect = 5e-10, Method: Compositional matrix adjust.
Identities = 41/137 (29%), Positives = 62/137 (45%), Gaps = 5/137 (3%)
Frame = -2
Query: 45 DIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWVPEVK 104
D+ VDG+ + +WDTAGQE Y LR Y TD L+ FSVD+ SL+++ + W E
Sbjct: 1050 DVVVDGETFTMQIWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLKSLQSLSD-WYDEFV 874
Query: 105 HFC-----PNVPIILVANKKDLRSDEHVRTELARMKQEPVRTDDGRAMAVRIQAYDYLEC 159
++ + P +++ NK D+ E V ++D Y E
Sbjct: 873 NYADIQDSASFPFVIIGNKADIEERE-------------VSSEDAYNWCRTHGNLPYFET 733
Query: 160 SAKTKEGVREVFETATR 176
SAK V++ F R
Sbjct: 732 SAKDSLNVQQAFLAVVR 682
>09700
Length = 1855
Score = 59.3 bits (142), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 29/73 (39%), Positives = 48/73 (65%)
Frame = -1
Query: 108 PNVPIILVANKKDLRSDEHVRTELARMKQEPVRTDDGRAMAVRIQAYDYLECSAKTKEGV 167
P P++LV + DLR+D V ELA+ K++PV DD +A ++ A Y+ECSA T++ +
Sbjct: 1822 PRTPLVLVGTQSDLRNDVKVLIELAKYKEKPVSEDDASKLAHQLGA-SYVECSALTQKNL 1646
Query: 168 REVFETATRAALQ 180
+E+F++ +LQ
Sbjct: 1645 KEMFDSCILTSLQ 1607
>01972
Length = 2359
Score = 50.1 bits (118), Expect(2) = 2e-09, Method: Compositional matrix adjust.
Identities = 24/71 (33%), Positives = 40/71 (56%)
Frame = +3
Query: 52 QVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWVPEVKHFCPNVP 111
+++ +WDTAGQE + LR Y ++ F V S + +N+P W ++ C N+P
Sbjct: 444 KLKFNVWDTAGQEKFGGLRDGYYIQGQCAVIMFDVTSRVTYKNVPN-WHRDLVRVCENIP 620
Query: 112 IILVANKKDLR 122
I+L NK D++
Sbjct: 621 IVLCGNKVDIK 653
Score = 27.7 bits (60), Expect(2) = 2e-09, Method: Compositional matrix adjust.
Identities = 13/30 (43%), Positives = 17/30 (56%)
Frame = +1
Query: 7 KLVVVGDGACGKTCLLIVFSKDEFPEVYVP 36
KLV+VGDG GKT + EF + +P
Sbjct: 307 KLVLVGDGGVGKTTFVKRHVTGEFEKNMLP 396
>27191
Length = 443
Score = 58.2 bits (139), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 32/103 (31%), Positives = 56/103 (54%), Gaps = 2/103 (1%)
Frame = +1
Query: 18 KTCLLIVFSKDEFPEVYVPTVFENYVADIE-VDGKQVELALWDTAGQEDYDRLRPLSYPD 76
KTCL+ F + +F + Y PTV +Y I+ V+G + + +WD +G +Y +R Y
Sbjct: 1 KTCLIKHFCESKFNQGYQPTVGVDYGFKIQTVNGVDMRVHMWDLSGSNEYLDVRNELYTG 180
Query: 77 TDVILMCFSVDSPDSLENIPEKWVPEVKHFCPNVPI-ILVANK 118
+D I + F V + S E + + W+ E+ F P+ ++V N+
Sbjct: 181 SDAIFIVFDVSNTPSFEAL-DSWLREINRFATGSPLNVIVGNR 306
>33374
Length = 489
Score = 55.5 bits (132), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 35/124 (28%), Positives = 56/124 (45%), Gaps = 1/124 (0%)
Frame = +1
Query: 48 VDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWVPEV-KHF 106
+D V+ +WDTAGQE Y L P+ Y ++ + + + D+ + WV E+ +
Sbjct: 160 LDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQDTFGR-AKTWVKELQRQA 336
Query: 107 CPNVPIILVANKKDLRSDEHVRTELARMKQEPVRTDDGRAMAVRIQAYDYLECSAKTKEG 166
PN+ I L NK DL + V E A+ E + ++E SAKT
Sbjct: 337 SPNIVIALAGNKADLANKRMVEFEEAQAYAEE-------------NSLLFMETSAKTAMN 477
Query: 167 VREV 170
V ++
Sbjct: 478 VNDI 489
>13750
Length = 503
Score = 52.8 bits (125), Expect = 9e-08, Method: Compositional matrix adjust.
Identities = 43/156 (27%), Positives = 61/156 (39%), Gaps = 2/156 (1%)
Frame = -2
Query: 18 KTCLLIVFSKDEFPEVYVPT--VFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYP 75
KTCLL + K F + +PT V + + D V LWDT G E Y L +
Sbjct: 502 KTCLLRRYQKGFFMDRTMPTIAVLCSEFNESRTDPLNVRYTLWDTGGAETYRSLWVSHFR 323
Query: 76 DTDVILMCFSVDSPDSLENIPEKWVPEVKHFCPNVPIILVANKKDLRSDEHVRTELARMK 135
V L+ + V S W + P +I V +K DL + + TE
Sbjct: 322 GAQVALLVYDVTCEWSFLTATTVWRKALMKNIPEAQVIFVGSKTDLEENRVISTE----- 158
Query: 136 QEPVRTDDGRAMAVRIQAYDYLECSAKTKEGVREVF 171
G+A A + Y + E S+ T + V VF
Sbjct: 157 -------RGQAFATQC-GYTFFETSSVTGKNVDAVF 74
>34359
Length = 1042
Score = 49.3 bits (116), Expect = 9e-07, Method: Compositional matrix adjust.
Identities = 24/70 (34%), Positives = 38/70 (54%)
Frame = +3
Query: 53 VELALWDTAGQEDYDRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWVPEVKHFCPNVPI 112
+ +WDTAGQE + LR Y ++ F V S + +N+P W ++ C N+PI
Sbjct: 195 LRFNVWDTAGQEKFGGLRDGYYIQGTCAIIMFDVTSRVTYKNVPN-WHRDLVRVCENIPI 371
Query: 113 ILVANKKDLR 122
+L NK D++
Sbjct: 372 VLCGNKVDIK 401
>26536
Length = 829
Score = 49.3 bits (116), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 37/129 (28%), Positives = 57/129 (44%), Gaps = 2/129 (1%)
Frame = +2
Query: 51 KQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSVDSPDSLENIPE--KWVPEVKHFCP 108
++V DTAGQE+Y +R D ++ +SV S + +W+ +
Sbjct: 122 RRVSWTFLDTAGQEEYSSMREHYTRSGDGFIVVYSVTDVTSFQEAEAVFRWLTRFQD-ET 298
Query: 109 NVPIILVANKKDLRSDEHVRTELARMKQEPVRTDDGRAMAVRIQAYDYLECSAKTKEGVR 168
++ +L NK DL SD V E +GR MA R+ Y E SAKT + V
Sbjct: 299 SIHAVLCGNKTDLTSDRKVTPE------------EGRKMADRLGML-YFETSAKTGDNVS 439
Query: 169 EVFETATRA 177
+V+ R+
Sbjct: 440 QVYHGLLRS 466
Score = 44.3 bits (103), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 19/45 (42%), Positives = 31/45 (68%)
Frame = +2
Query: 7 KLVVVGDGACGKTCLLIVFSKDEFPEVYVPTVFENYVADIEVDGK 51
K+V++G G GK+ L I F++D F +VY PT+ ++Y I+V G+
Sbjct: 491 KIVMLGSGGVGKSSLTIRFTQDTFLDVYDPTIEDSYRKMIQVSGQ 625
>35581
Length = 364
Score = 47.8 bits (112), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 29/94 (30%), Positives = 43/94 (45%), Gaps = 2/94 (2%)
Frame = +2
Query: 7 KLVVVGDGACGKTCLLIVFSKDEFPE--VYVPTVFENYVADIEVDGKQVELALWDTAGQE 64
K V++GD GKTCLL + D+F + + T G + LWDTAGQE
Sbjct: 50 KCVLLGDAGVGKTCLLNRLATDKFLDSPLTSLTTASLLTTVTLTSGVMASVDLWDTAGQE 229
Query: 65 DYDRLRPLSYPDTDVILMCFSVDSPDSLENIPEK 98
Y L Y DT +L+ + + L + ++
Sbjct: 230 RYRSLTSSYYRDTKAVLIVYDAEHKLKLTDWTDR 331
>33380
Length = 282
Score = 47.4 bits (111), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 27/78 (34%), Positives = 42/78 (53%), Gaps = 1/78 (1%)
Frame = +3
Query: 51 KQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWVPEVKHFC-PN 109
K+V+L +WDTAGQE Y + Y ++ + V + +S N + W ++K + N
Sbjct: 54 KRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDVTNEESF-NAVQDWCTQIKTYSWDN 230
Query: 110 VPIILVANKKDLRSDEHV 127
++LV NK DL DE V
Sbjct: 231 AQVVLVGNKCDL-EDERV 281
>33794
Length = 779
Score = 47.0 bits (110), Expect = 5e-06, Method: Compositional matrix adjust.
Identities = 27/88 (30%), Positives = 49/88 (55%), Gaps = 1/88 (1%)
Frame = -1
Query: 46 IEVDGKQVELALWDTAGQEDY-DRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWVPEVK 104
I ++GK+V+L +WDT+GQ + +R S +IL+ + + + S + I ++W+ EV+
Sbjct: 671 ILLEGKRVKLQIWDTSGQGRFCTIIRSYSRGAQGIILV-YDITNKWSFDGI-DRWLKEVE 498
Query: 105 HFCPNVPIILVANKKDLRSDEHVRTELA 132
P +P +LV N+ L V + A
Sbjct: 497 EHAPGIPKVLVGNRLHLAYKRQVAAKQA 414
>13901
Length = 962
Score = 46.6 bits (109), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 23/90 (25%), Positives = 44/90 (48%), Gaps = 2/90 (2%)
Frame = -3
Query: 7 KLVVVGDGACGKTCLLIVFSKDEFPEVYVPTVFENYVADI--EVDGKQVELALWDTAGQE 64
K++++GD GKT + + D F Y T+ ++ + D ++L LWD AGQE
Sbjct: 282 KVIIIGDPTVGKTSFVQRYVNDSFRRDYKMTIGVDFALKVIRWSDKCNIKLQLWDIAGQE 103
Query: 65 DYDRLRPLSYPDTDVILMCFSVDSPDSLEN 94
+ + + Y D ++ F + ++ +N
Sbjct: 102 RFTSMTRVYYKDAHACIVMFDLTQKNTYQN 13
>00552
Length = 455
Score = 43.5 bits (101), Expect = 5e-05, Method: Compositional matrix adjust.
Identities = 22/51 (43%), Positives = 31/51 (60%)
Frame = -3
Query: 56 ALWDTAGQEDYDRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWVPEVKHF 106
+WDTAGQE Y LR Y TD L+ FSVD+ SL+++ + W E ++
Sbjct: 150 GIWDTAGQERYKSLRTPFYRGTDCCLLTFSVDNLKSLQSLSD-WYDEFVNY 1
>05468
Length = 1558
Score = 42.7 bits (99), Expect = 9e-05, Method: Compositional matrix adjust.
Identities = 32/122 (26%), Positives = 56/122 (45%), Gaps = 8/122 (6%)
Frame = -3
Query: 7 KLVVVGDGACGKTCLLIVFSKDEFPEVYVPTV---FENYVADIEVDGKQVELALWDTAGQ 63
K++V+G+ GKT ++ + F + Y T+ F V + + D + L LWD AGQ
Sbjct: 1535 KILVIGELGTGKTSIIKRYVHQFFSQHYRATIGVDFALKVLNWDAD-TLIRLQLWDIAGQ 1359
Query: 64 EDYDRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWVPEVKHFC-----PNVPIILVANK 118
E + + + Y + + F V + + + KW ++ VP +L+ANK
Sbjct: 1358 ERFGNMTRVYYKEAVGAFVVFDVTRASTFDAVT-KWKNDLDSKVQLADGSPVPCVLLANK 1182
Query: 119 KD 120
D
Sbjct: 1181 CD 1176
>32770
Length = 387
Score = 42.4 bits (98), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 26/84 (30%), Positives = 39/84 (46%), Gaps = 2/84 (2%)
Frame = +2
Query: 101 PEVKHFCPNVPIILVANKKDLRSDEHVRTELARMKQEPVRTDDGRAMAVRIQAYDYLECS 160
PE++ + P P ILV + DLR ++ + V G+ +A ++ A Y ECS
Sbjct: 2 PELRDYRPGTPFILVGTQADLRHHSQPASK------DMVPAHKGKKLARKVGALGYFECS 163
Query: 161 AKTKEGVREVFETATRAAL--QKR 182
A G+ VF A+ QKR
Sbjct: 164 ALIGSGLDRVFRQVVTCAVHPQKR 235
>28321
Length = 422
Score = 36.6 bits (83), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 18/31 (58%), Positives = 23/31 (74%)
Frame = +2
Query: 162 KTKEGVREVFETATRAALQKRYGSQNGCINC 192
+ KEGVREVFETATRAALQ + + ++C
Sbjct: 32 QXKEGVREVFETATRAALQTKKKKKVVVLSC 124
>08153
Length = 1703
Score = 36.2 bits (82), Expect = 0.009, Method: Compositional matrix adjust.
Identities = 36/122 (29%), Positives = 57/122 (46%), Gaps = 7/122 (5%)
Frame = +1
Query: 7 KLVVVGDGACGKTCLLIVFSKDEFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDY 66
++++VG A GKT +L E +PT+ N V+ K + +WD GQ
Sbjct: 88 RILMVGLDAAGKTTILYKLKLGEIVTT-IPTIGFNVET---VEYKNISFTVWDVGGQ--- 246
Query: 67 DRLRPL---SYPDTDVILMCFSVDSPDSLENIPEKWVPEVKHF----CPNVPIILVANKK 119
D++RPL + +T ++ F VDS D E I E + + I++ ANK+
Sbjct: 247 DKIRPLWRHYFQNTQGLI--FVVDSNDR-ERINEAKEELARMLNEDDLRDAIILVFANKQ 417
Query: 120 DL 121
DL
Sbjct: 418 DL 423
>09827
Length = 1201
Score = 35.4 bits (80), Expect = 0.015, Method: Compositional matrix adjust.
Identities = 34/122 (27%), Positives = 57/122 (46%), Gaps = 7/122 (5%)
Frame = -3
Query: 7 KLVVVGDGACGKTCLLIVFSKDEFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDY 66
++++VG A GKT +L E +PT+ N V+ K + +WD GQ
Sbjct: 1109 RILMVGLDAAGKTTILYKLKLGEIVTT-IPTIGFNVET---VEYKNISFTVWDVGGQ--- 951
Query: 67 DRLRPL---SYPDTDVILMCFSVDSPDSLENIPEKWVPEVKHF----CPNVPIILVANKK 119
D++RPL + +T ++ F VDS D E + E + + +++ ANK+
Sbjct: 950 DKIRPLWRHYFQNTQGLI--FVVDSNDK-ERVQEAREELTRMLNEDELRDAVLLVFANKQ 780
Query: 120 DL 121
DL
Sbjct: 779 DL 774
>14775
Length = 380
Score = 34.3 bits (77), Expect = 0.035, Method: Compositional matrix adjust.
Identities = 23/71 (32%), Positives = 31/71 (43%), Gaps = 2/71 (2%)
Frame = -2
Query: 18 KTCLLIVFSKDEFPEVYVPT--VFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYP 75
KTCLL + K F + +PT V + + D V LWDT G E Y L +
Sbjct: 379 KTCLLRRYQKGFFMDRTMPTIAVLCSEFNESRTDPLNVRYTLWDTGGAETYRSLWVSHFR 200
Query: 76 DTDVILMCFSV 86
V L+ + V
Sbjct: 199 GAQVALLVYDV 167
>29380
Length = 853
Score = 34.3 bits (77), Expect = 0.035, Method: Compositional matrix adjust.
Identities = 30/109 (27%), Positives = 48/109 (44%), Gaps = 2/109 (1%)
Frame = -2
Query: 81 LMCFSVDSPDSLENIPEKWVPEVKH-FCPNVPIILVANKKDLRSDEHVRTELARMKQEPV 139
++ + V+ D+ WV E++ +V IIL NK DL + + V
Sbjct: 840 IIVYDVNIADTFSR-ALAWVKELRQQNTESVLIILAGNKVDLAT-----------QHRAV 697
Query: 140 RTDDGRAMAVRIQAYDYLECSAKTKEGVREVFETATRAALQKRY-GSQN 187
+D ++ A R + E SAKT V E+F T +Q+ GS+N
Sbjct: 696 SFEDAQSFA-RENGLLFAEVSAKTGMAVNEIFMTLANQLIQQEIDGSRN 553
>14119
Length = 602
Score = 34.3 bits (77), Expect = 0.037, Method: Compositional matrix adjust.
Identities = 28/76 (36%), Positives = 33/76 (43%), Gaps = 1/76 (1%)
Frame = +1
Query: 99 WVPEVKH-FCPNVPIILVANKKDLRSDEHVRTELARMKQEPVRTDDGRAMAVRIQAYDYL 157
WV E++ +V I+L NK DL S EH V DD R A +
Sbjct: 22 WVKELRQQNAGSVLIVLAGNKADLAS-EH----------RAVSADDARTFA-EDNGLIFA 165
Query: 158 ECSAKTKEGVREVFET 173
E SAKT V EVF T
Sbjct: 166 EVSAKTGMAVSEVFMT 213
>18509
Length = 625
Score = 33.5 bits (75), Expect = 0.060, Method: Compositional matrix adjust.
Identities = 23/69 (33%), Positives = 32/69 (46%), Gaps = 2/69 (2%)
Frame = -3
Query: 110 VPIILVANKKDLRSDEHVRTELARMKQEPVRTDDGRAMAVRIQAYD--YLECSAKTKEGV 167
VP++LV NK DL P+R + R + Y Y+E SAKT++GV
Sbjct: 527 VPMVLVGNKVDL----------------PIRNVEQRQGKHMAELYHIPYVETSAKTRQGV 396
Query: 168 REVFETATR 176
+ F T R
Sbjct: 395 DDAFYTLVR 369
>36757
Length = 359
Score = 32.7 bits (73), Expect = 0.092, Method: Compositional matrix adjust.
Identities = 14/24 (58%), Positives = 19/24 (79%)
Frame = +2
Query: 156 YLECSAKTKEGVREVFETATRAAL 179
YLECSA T++G++ VF+ A RA L
Sbjct: 8 YLECSALTQKGLKTVFDEAIRAVL 79
>36482
Length = 686
Score = 32.7 bits (73), Expect = 0.097, Method: Compositional matrix adjust.
Identities = 29/109 (26%), Positives = 46/109 (42%), Gaps = 2/109 (1%)
Frame = +2
Query: 21 LLIVFSKDEFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVI 80
L + F F Y PT+ Y ++ V L + DTAGQ Y + D
Sbjct: 2 LTVRFLTRRFIGEYCPTLESVYKYHTVIEDDDVRLEILDTAGQGTYPWKEGYALW-ADCF 178
Query: 81 LMCFSVDSPDSLENIPE--KWVPEVKHFCPNVPIILVANKKDLRSDEHV 127
+ +S++ S E + + + V V+ ++ +L ANK DL D V
Sbjct: 179 VFVYSINDRQSYEELVQVKRQVESVRK-STSLTAVLAANKTDLLHDRQV 322
>06994
Length = 429
Score = 32.0 bits (71), Expect = 0.16, Method: Compositional matrix adjust.
Identities = 14/29 (48%), Positives = 20/29 (68%)
Frame = +1
Query: 34 YVPTVFENYVADIEVDGKQVELALWDTAG 62
Y PT+ ++Y +EVDG+Q L + DTAG
Sbjct: 142 YDPTIEDSYRKQVEVDGQQCMLEILDTAG 228
>25618
Length = 475
Score = 31.2 bits (69), Expect = 0.32, Method: Compositional matrix adjust.
Identities = 25/67 (37%), Positives = 28/67 (41%)
Frame = +3
Query: 107 CPNVPIILVANKKDLRSDEHVRTELARMKQEPVRTDDGRAMAVRIQAYDYLECSAKTKEG 166
+V I+L NK DL S EH V DD R A + E SAKT
Sbjct: 69 AGSVLIVLAGNKADLAS-EH----------RAVSADDARTFA-EDNGLIFAEVSAKTGMA 212
Query: 167 VREVFET 173
V EVF T
Sbjct: 213 VSEVFMT 233
>13745
Length = 1045
Score = 29.6 bits (65), Expect = 0.76, Method: Compositional matrix adjust.
Identities = 31/128 (24%), Positives = 53/128 (41%), Gaps = 9/128 (7%)
Frame = +2
Query: 63 QEDYDRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWVPEV---------KHFCPNVPII 113
QE + L Y D ++ + V +P+S +N+ + W E +HF P +
Sbjct: 2 QERFQSLGVAFYRGADCCVLVYDVTAPNSFKNL-DSWRDEFLIQASPRDPEHF----PFV 166
Query: 114 LVANKKDLRSDEHVRTELARMKQEPVRTDDGRAMAVRIQAYDYLECSAKTKEGVREVFET 173
++ NK DL + R R Q+ ++ + Y E SAK V F+T
Sbjct: 167 VLGNKVDLDN----RQVSTRRAQQWCQSKND---------IPYYETSAKEGINVEMAFQT 307
Query: 174 ATRAALQK 181
+ AL++
Sbjct: 308 IAKNALEQ 331
>12443
Length = 837
Score = 29.3 bits (64), Expect = 1.1, Method: Compositional matrix adjust.
Identities = 26/104 (25%), Positives = 47/104 (45%), Gaps = 10/104 (9%)
Frame = -3
Query: 4 IRKKLVVVGDGACGKTCLLIVFSKDEFPEVY-----VPTVFENYVADIEVDGKQV--ELA 56
+ K+++VG GKT + + ++ P + + T + I+ GK V ++
Sbjct: 586 VNYKVMLVGKTGVGKTSTVAKLTGNDIPLTHNETPGLQTSHLYWPGKIKHLGKTVLFQIQ 407
Query: 57 LWDTAGQ---EDYDRLRPLSYPDTDVILMCFSVDSPDSLENIPE 97
L+D AG+ + YD + P D I+ FS S + IP+
Sbjct: 406 LFD-AGETALKRYDHILPACQDGVDGIMFLFSFVDKGSFDEIPQ 278
>12339
Length = 578
Score = 28.5 bits (62), Expect = 1.6, Method: Compositional matrix adjust.
Identities = 30/123 (24%), Positives = 51/123 (41%), Gaps = 4/123 (3%)
Frame = -2
Query: 63 QEDYDRLRPLSYPDTDVILMCFSV---DSPDSLENIPEKWVPEVKHFCP-NVPIILVANK 118
QE + L Y D ++ + V + DSL++ +++ + P + P +++ NK
Sbjct: 577 QERFQSLGVAFYRGADCCILVYDVTEXKTFDSLDSWQREFLNQASPRDPEHFPFVVIGNK 398
Query: 119 KDLRSDEHVRTELARMKQEPVRTDDGRAMAVRIQAYDYLECSAKTKEGVREVFETATRAA 178
DL + R A+ Q T G Y E SAK V + F+T + A
Sbjct: 397 IDLDN----RVVTAKRGQGWCSTKGG---------IPYFETSAKEAINVEQAFQTVAKNA 257
Query: 179 LQK 181
L +
Sbjct: 256 LAQ 248
>19819
Length = 717
Score = 26.9 bits (58), Expect = 5.2, Method: Compositional matrix adjust.
Identities = 16/38 (42%), Positives = 19/38 (50%), Gaps = 1/38 (2%)
Frame = +2
Query: 36 PTVFENYVADI-EVDGKQVELALWDTAGQEDYDRLRPL 72
P V N V+ + E G Q LWDTAG E L+ L
Sbjct: 116 PVVHGNVVSPVPEY*GSQESSILWDTAGTEGVPLLKVL 229
>04861
Length = 3205
Score = 26.6 bits (57), Expect = 6.4, Method: Compositional matrix adjust.
Identities = 12/39 (30%), Positives = 21/39 (53%)
Frame = -1
Query: 105 HFCPNVPIILVANKKDLRSDEHVRTELARMKQEPVRTDD 143
H PN+P +L NK+ L + T L ++Q +++ D
Sbjct: 460 HHYPNLPSLLYKNKRKLIPQHNQYTTLVSIEQSVMQSGD 344
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000380987 | hsapiens_gene_ensembl |
Dihydropyrimidinase-related protein 1 (DRP-1) (Collapsin response
mediator protein 1) (CRMP-1). [Source:Uniprot/SWISSPROT;Acc:Q14194]
(572 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
14768 214 6e-71
34622 162 2e-40
29305 37 0.021
>14768
Length = 697
Score = 214 bits (545), Expect(2) = 6e-71, Method: Compositional matrix adjust.
Identities = 95/161 (59%), Positives = 127/161 (78%)
Frame = -1
Query: 322 ACGDLQVTGSGHCPYSTAQKAVGKDNFTLIPEGVNGIEERMTVVWDKAVATGKMDENQFV 381
A DLQVTG+ +C + QKA+GKD+F IP GVNG+E+RM+V+W+K V +GKMD +FV
Sbjct: 487 ANNDLQVTGTDNCTFRADQKALGKDDFRSIPNGVNGVEDRMSVIWEKGVQSGKMDACRFV 308
Query: 382 AVTSTNAAKIFNLYPRKGRIAVGSDADVVIWDPDKLKTITAKSHKSAVEYNIFEGMECHG 441
AVTS+ AAKIFN+YPRKGRIAVGSDADVV+WD ++ +TI+A++H AV++NIFEG++CHG
Sbjct: 307 AVTSSAAAKIFNIYPRKGRIAVGSDADVVVWDGNQTRTISAETHHQAVDFNIFEGLQCHG 128
Query: 442 SPLVVISQGKIVFEDGNINVNKGMGRFIPRKAFPEHLYQRV 482
P+ VI G +V ++G + V KG GRFIP FPE +Y R+
Sbjct: 127 VPVYVIXNGNVVVDNGEVKVTKGSGRFIPSPCFPEAVYGRI 5
Score = 72.0 bits (175), Expect(2) = 6e-71, Method: Compositional matrix adjust.
Identities = 31/51 (60%), Positives = 41/51 (80%)
Frame = -2
Query: 252 ITKVMSKSAADIIALARKKGPLVFGEPIAASLGTDGTHYWSKNWAKAAAFV 302
+ +MSKS+AD+I+ +R+KG +VFGEPIAASLGTDGTH W++ W AA V
Sbjct: 696 VVHIMSKSSADVISASRRKGKVVFGEPIAASLGTDGTHQWNRCWRHAAGHV 544
>34622
Length = 477
Score = 162 bits (411), Expect = 2e-40, Method: Compositional matrix adjust.
Identities = 69/128 (53%), Positives = 100/128 (78%)
Frame = -3
Query: 360 ERMTVVWDKAVATGKMDENQFVAVTSTNAAKIFNLYPRKGRIAVGSDADVVIWDPDKLKT 419
+RM+V+W+K V GKMD +FVA TS NAA+I+N+YPRKGRIAVGSDADVV+WD ++ +T
Sbjct: 475 DRMSVIWEKGVMMGKMDACRFVAATSANAARIYNIYPRKGRIAVGSDADVVVWDGNQTRT 296
Query: 420 ITAKSHKSAVEYNIFEGMECHGSPLVVISQGKIVFEDGNINVNKGMGRFIPRKAFPEHLY 479
I+A++H AV++NIFEG++CHG P+ V+S G++V +DG + V +G+GR + E +Y
Sbjct: 295 ISAETHHQAVDFNIFEGLQCHGVPVYVVSNGQVVVDDGQLKVTQGLGRLVSTPCNAETVY 116
Query: 480 QRVKIRNK 487
RVK R++
Sbjct: 115 GRVKARDQ 92
>29305
Length = 881
Score = 37.0 bits (84), Expect = 0.021, Method: Compositional matrix adjust.
Identities = 16/23 (69%), Positives = 19/23 (82%)
Frame = -3
Query: 86 ADDFFQGTRAALVGGTTMIIDHV 108
DDF+ GT+AAL GGTTMI+D V
Sbjct: 879 CDDFYIGTKAALAGGTTMIMDFV 811
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000321606 | hsapiens_gene_ensembl |
Dihydropyrimidinase-related protein 1 (DRP-1) (Collapsin response
mediator protein 1) (CRMP-1). [Source:Uniprot/SWISSPROT;Acc:Q14194]
(686 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
14768 214 9e-71
34622 163 3e-40
29305 39 0.009
>14768
Length = 697
Score = 214 bits (544), Expect(2) = 9e-71, Method: Compositional matrix adjust.
Identities = 95/161 (59%), Positives = 127/161 (78%)
Frame = -1
Query: 436 ACGDLQVTGSGHCPYSTAQKAVGKDNFTLIPEGVNGIEERMTVVWDKAVATGKMDENQFV 495
A DLQVTG+ +C + QKA+GKD+F IP GVNG+E+RM+V+W+K V +GKMD +FV
Sbjct: 487 ANNDLQVTGTDNCTFRADQKALGKDDFRSIPNGVNGVEDRMSVIWEKGVQSGKMDACRFV 308
Query: 496 AVTSTNAAKIFNLYPRKGRIAVGSDADVVIWDPDKLKTITAKSHKSAVEYNIFEGMECHG 555
AVTS+ AAKIFN+YPRKGRIAVGSDADVV+WD ++ +TI+A++H AV++NIFEG++CHG
Sbjct: 307 AVTSSAAAKIFNIYPRKGRIAVGSDADVVVWDGNQTRTISAETHHQAVDFNIFEGLQCHG 128
Query: 556 SPLVVISQGKIVFEDGNINVNKGMGRFIPRKAFPEHLYQRV 596
P+ VI G +V ++G + V KG GRFIP FPE +Y R+
Sbjct: 127 VPVYVIXNGNVVVDNGEVKVTKGSGRFIPSPCFPEAVYGRI 5
Score = 72.4 bits (176), Expect(2) = 9e-71, Method: Compositional matrix adjust.
Identities = 31/51 (60%), Positives = 41/51 (80%)
Frame = -2
Query: 366 ITKVMSKSAADIIALARKKGPLVFGEPIAASLGTDGTHYWSKNWAKAAAFV 416
+ +MSKS+AD+I+ +R+KG +VFGEPIAASLGTDGTH W++ W AA V
Sbjct: 696 VVHIMSKSSADVISASRRKGKVVFGEPIAASLGTDGTHQWNRCWRHAAGHV 544
>34622
Length = 477
Score = 163 bits (412), Expect = 3e-40, Method: Compositional matrix adjust.
Identities = 69/128 (53%), Positives = 100/128 (78%)
Frame = -3
Query: 474 ERMTVVWDKAVATGKMDENQFVAVTSTNAAKIFNLYPRKGRIAVGSDADVVIWDPDKLKT 533
+RM+V+W+K V GKMD +FVA TS NAA+I+N+YPRKGRIAVGSDADVV+WD ++ +T
Sbjct: 475 DRMSVIWEKGVMMGKMDACRFVAATSANAARIYNIYPRKGRIAVGSDADVVVWDGNQTRT 296
Query: 534 ITAKSHKSAVEYNIFEGMECHGSPLVVISQGKIVFEDGNINVNKGMGRFIPRKAFPEHLY 593
I+A++H AV++NIFEG++CHG P+ V+S G++V +DG + V +G+GR + E +Y
Sbjct: 295 ISAETHHQAVDFNIFEGLQCHGVPVYVVSNGQVVVDDGQLKVTQGLGRLVSTPCNAETVY 116
Query: 594 QRVKIRNK 601
RVK R++
Sbjct: 115 GRVKARDQ 92
>29305
Length = 881
Score = 38.5 bits (88), Expect = 0.009, Method: Composition-based stats.
Identities = 16/22 (72%), Positives = 19/22 (86%)
Frame = -3
Query: 201 DDFFQGTRAALVGGTTMIIDHV 222
DDF+ GT+AAL GGTTMI+D V
Sbjct: 876 DDFYIGTKAALAGGTTMIMDFV 811
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000355759 | hsapiens_gene_ensembl | Poly
[ADP-ribose] polymerase 1 (EC 2.4.2.30) (PARP-1) (ADPRT) (NAD(+)
ADP-ribosyltransferase 1) (Poly[ADP-ribose] synthetase 1).
[Source:Uniprot/SWISSPROT;Acc:P09874]
(1014 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
07234 263 2e-70
06293 239 4e-63
10167 184 1e-46
16273 136 3e-32
04480 120 4e-27
11193 74 3e-13
31070 35 0.15
32072 33 0.52
>07234
Length = 543
Score = 263 bits (673), Expect = 2e-70, Method: Compositional matrix adjust.
Identities = 119/173 (68%), Positives = 148/173 (85%)
Frame = -2
Query: 784 DSSKDPIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDIFKIEREG 843
D +DPID +Y+KLK ++ +D + + + +YV+NTHA TH Y L+V+DIF+++REG
Sbjct: 521 DKGEDPIDAHYKKLKCTMEPLDNKGDMFKRLCEYVQNTHAATHQQYTLDVLDIFEMDREG 342
Query: 844 ECQRYKPFKQLHNRRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSK 903
E Q+++PFK LHNR+LLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSK
Sbjct: 341 ETQQFEPFKALHNRQLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSK 162
Query: 904 SANYCHTSQGDPIGLILLGEVALGNMYELKHASHISKLPKGKHSVKGLGKTTP 956
SANYC TS+ DPIG++LL EVALGNM+EL AS+++KLPKGKHS KG+G+TTP
Sbjct: 161 SANYCRTSKADPIGILLLCEVALGNMHELTSASYVTKLPKGKHSTKGIGRTTP 3
>06293
Length = 2053
Score = 239 bits (610), Expect = 4e-63, Method: Compositional matrix adjust.
Identities = 142/405 (35%), Positives = 218/405 (53%), Gaps = 31/405 (7%)
Frame = +2
Query: 515 GINKSEKRMKLTLKGGAAVDPDSGLEHSAHVLEKGGKVFSATLGLVDIVKGTNSYYKLQL 574
G KS R + KG A VD + L V E ++ L ++ N YY +Q+
Sbjct: 86 GDTKSVVRQVVVNKGSAPVDAECPLAGKCRVYEAASTIWDCMLNQTNVGNNNNKYYIIQV 265
Query: 575 LEDDKENRYWIFRSWGRVGTVIGSNKLEQMPSKEDAIEHFMKLYEEKTGNAWHSKN-FTK 633
LED + Y +++ WGRVG +N + AI+ F K +++KT N W+++N F K
Sbjct: 266 LEDTSKKAYHVWQRWGRVGYKGQTNLVNTGGDLNKAIDVFSKKFQDKTKNHWNNRNNFLK 445
Query: 634 YPKKFYPLEIDYGQDEEAVKKLTVNPGTK----------SKLPKPVQDLIKMIFDVESMK 683
P K+ + +DY EE V+ G SKL + VQDL+KMI DV+SM+
Sbjct: 446 VPGKYDLVHLDYSAKEED----QVDAGEAGDNEDSQAPDSKLHQKVQDLVKMICDVKSME 613
Query: 684 KAMVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQGSSDSQILDLSNRFYTLIPHD 743
+A+VE + D +K PLGKL+K QI A Y L E++ ++ + D + FYT IPHD
Sbjct: 614 EAVVEMKYDAKKAPLGKLTKDQITAGYESLKEIESLINTKDFGRNLTDACSEFYTRIPHD 793
Query: 744 FGMKKPPLLNNADSVQAKVEMLDNLLDIEVAYSLLRGGSDDSSKDPIDVNYEKLKTDIKV 803
FGM+ PP++ V+ K+++L+ L DI+ A +L+ G D S++P+D +Y L +
Sbjct: 794 FGMRTPPVIRTPKEVKEKLQLLEALEDIQYAIKMLKQG--DKSENPVDRHYHSLACALSP 967
Query: 804 VDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDIFKIEREGECQRYKPFKQLHNRRLLWHG 863
+D S++ ++I Y+ THA THN Y +++++++ ++++GE +RY + NR LLWHG
Sbjct: 968 LDHGSDDFKLIESYLLETHAATHNQYKMKLLELYDVDKQGEKERYLDYG---NRMLLWHG 1138
Query: 864 SRTTNFAGILSQG--------------------LRIAPPEAPVTG 888
SR TN+AGIL QG LR P P T
Sbjct: 1139SRLTNWAGILGQG*GSHPQRPRSQDTCLGKVCILRTCPARVPTTA 1273
Score = 142 bits (357), Expect = 8e-34, Method: Compositional matrix adjust.
Identities = 80/162 (49%), Positives = 101/162 (62%), Gaps = 5/162 (3%)
Frame = +1
Query: 841 REGECQRYKPFKQLHNRRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADM 900
REGE R L + + G GLRIAPPEAPVTGYMFGKG+YFADM
Sbjct: 1087 REGEISR------LRQQDVAVARVSADQLGGYPGSGLRIAPPEAPVTGYMFGKGVYFADM 1248
Query: 901 VSKSANYCHTSQGDPIGLILLGEVALGNMYELKHASHIS-KLPKGKHSVKGLGKTTPDPS 959
SKSANYC S+ +G++LL +V+LGN+ E A + + KLP GKHSVKG G PDPS
Sbjct: 1249 SSKSANYCFASKQKNVGMMLLCDVSLGNINEKLDADYYADKLPSGKHSVKGCGSVGPDPS 1428
Query: 960 A-NISLDGVDVPLGTGISSGVNDT---SLLYNEYIVYDIAQV 997
DG+ VP+G G ++GV + +L YNE+IVY+ AQ+
Sbjct: 1429 TFKTQPDGLVVPVGKGTNTGVTNPKGYTLNYNEFIVYNTAQI 1554
>10167
Length = 959
Score = 184 bits (468), Expect = 1e-46, Method: Composition-based stats.
Identities = 126/352 (35%), Positives = 176/352 (50%), Gaps = 32/352 (9%)
Frame = -1
Query: 566 TNSYYKLQLLEDDKENRYWIFRSWGRVGTVIGSNKLE---QMPSKEDAIEHFMKLYEEKT 622
TNS+YKLQ LE D N YW++R+WGRVGT +G+ + Q P + E T
Sbjct: 959 TNSFYKLQALEGDSANSYWLYRAWGRVGTTVGATRWRGAGQRPV*LTSSVSCT*AKREMT 780
Query: 623 GNAWHSKNFTKYPKKFYPLEIDYGQDEEAVKKLTVNPGTKSKLPKPVQDLIKMIFDVESM 682
G+ S N ++ L + P P + + M
Sbjct: 779 GS---SANTSRNNPTSSTLLTLTTDRRTRPSRS*RCPTPTPSWPSQCRT*SVSSLTWDQM 609
Query: 683 KKAMVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQGSSDSQILDLSNRFYTLIPH 742
KKAM+E+EID++KMPLGKLSKRQI++AY +L+E+Q V++ + +Q +D +NRFYTLIPH
Sbjct: 608 KKAMMEFEIDMKKMPLGKLSKRQIESAYKVLTELQDLVTKKGTQTQFVDATNRFYTLIPH 429
Query: 743 DFGMKKPPLLNNADSVQAKVEMLDNLLDIEVAYSLLRGGSDDSSKDPIDVNYEKLKTDIK 802
DFGM K LL+ +++++K EMLDNLL+IEVAYSLLRGG D + P
Sbjct: 428 DFGMGKIKLLDTEEAIKSKTEMLDNLLEIEVAYSLLRGG--DKRRRP------------- 294
Query: 803 VVDRDSEEAEII-------RKYVKNT------HATTHNAY----------------DLEV 833
R +E ++ R++V+ T H+ H + D V
Sbjct: 293 -HRRSLQETQVYHGAFGQ*RRHVQATV*ICTEHSRCHTSTVHTGRSGYL*NGS*GGDTAV 117
Query: 834 IDIFKIEREGECQRYKPFKQLHNRRLLWHGSRTTNFAGILSQGLRIAPPEAP 885
I +G Q ++ + +L AGILSQGLRIAPPEAP
Sbjct: 116 *TI-----QGSAQSSVVVARVSDHQL----------AGILSQGLRIAPPEAP 6
>16273
Length = 967
Score = 136 bits (343), Expect = 3e-32, Method: Compositional matrix adjust.
Identities = 81/244 (33%), Positives = 123/244 (50%), Gaps = 2/244 (0%)
Frame = -3
Query: 241 QNDLIWNIKDELKKVCSTNDLKELLIFNKQQVPSGESAILDRVADGMVFGALLPCEEC-S 299
Q+ +IW +D L K + + +K +L N Q++P GES +LD ++D + FGAL PC EC
Sbjct: 767 QSQMIWKFRDALVKDVANDAMKVMLELNAQKIPPGESKLLDAMSDCLAFGALDPCAECKD 588
Query: 300 GQLVFKSDAYYCTGDVTAWTKCMVKTQTPNRKEWVTPKEFREISYLKKLKVKKQDRIFXX 359
GQLV+ ++ Y CTG+VT WTKCM T+TP R+ + P EF ++ +LK K K+ R F
Sbjct: 587 GQLVYTAEGYKCTGNVTEWTKCMNITKTPTRRAFKVPAEFHDVPFLKSYKYVKRQRAFPT 408
Query: 360 XXXXXXXXXXXXXXXXXXXXXXXXXXXDKPLSNMKILTLGKLSRNKDEVKAMIEKLGGK- 418
KPL +K + + K S++K + IE LGG
Sbjct: 407 ITIAANVGPVSSSMDAVDGPSSS-----KPLDGLKFVLVCK-SKDKARLTKDIEGLGGSV 246
Query: 419 LTGTANKASLCISTXXXXXXXXXXXXXXXXANIRVVSEDFLQDVSASTKSLQELFLAHIL 478
L+ K + C+S+ A+I+VV EDF++ + +L + L
Sbjct: 245 LSKPDAKTAACVSSKEDVEKLGKAMKGVKEADIQVVPEDFVEKAKQGA-VVTDLIKSLNL 69
Query: 479 SPWG 482
+PWG
Sbjct: 68 APWG 57
>04480
Length = 1878
Score = 120 bits (300), Expect = 4e-27, Method: Compositional matrix adjust.
Identities = 76/210 (36%), Positives = 111/210 (52%), Gaps = 3/210 (1%)
Frame = -3
Query: 791 DVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDIFKIEREGECQRYKP 850
D Y + + I+ + + E + + Y+ A+ H +V ++K+ R GE + K
Sbjct: 1828 DYIYRSMGSKIQPLSENEHETQYLLTYIN---ASGHGC---KVNAVYKVSRPGEVEALKD 1667
Query: 851 FKQLHNRRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANYCHT 910
LHN RLLWHG+ N ILS+GL +AP AP G FG+G+YFAD +KS +YC+
Sbjct: 1666 VG-LHNHRLLWHGTSMANIVSILSRGLLVAPANAPRNGNAFGEGVYFADCFTKSRSYCYN 1490
Query: 911 SQGDPIGLILLGEVALGNMYELKHASHISKLPKGKHSVKGLGKTTPDPSANISLD-GVDV 969
+ G ++LL +VALGN E + HS+K LG PDP +I L G +
Sbjct: 1489 AVGS-CKVMLLCQVALGNSLEDLCHDEEDHHDEDVHSLKVLGCMQPDPDFDIVLPYGATL 1313
Query: 970 PLGT--GISSGVNDTSLLYNEYIVYDIAQV 997
PLG ++ SL YNEYIV++ Q+
Sbjct: 1312 PLGQLKKMTYDGKTPSLQYNEYIVHNPQQI 1223
>11193
Length = 1001
Score = 74.3 bits (181), Expect = 3e-13, Method: Compositional matrix adjust.
Identities = 60/218 (27%), Positives = 103/218 (47%), Gaps = 23/218 (10%)
Frame = -2
Query: 547 EKGGKVFSATLGLVDIVKGT---NSYYKLQLLEDDKENRYWIFRSWGRVGTVIGSNKLEQ 603
E K + TL VD+ GT ++YK+Q++ ++ Y +F WGR+G G +
Sbjct: 718 ETKNKTYDITLTKVDVSTGTWGMYNFYKIQIVRQKAKDMYVLFTRWGRIGDR-GQWQHTP 542
Query: 604 MPSKEDAIEHFMKLYEEKTGNAW-HSKNFTKYPKKFYPLEIDYGQDEEAVKKLTVN--PG 660
P+ EDAI+ F K++ +KTGN W H + F ++ KK+ + ++ + K +T N
Sbjct: 541 FPTAEDAIKEFCKVFRQKTGNDWNHLEKFVEHKKKYRLMPT--LEEPKRSKAVTFNFQSP 368
Query: 661 TKSKLPKPVQDLIKMIFDVESMKKAMVEYEIDLQKMPLGKLSKRQIQAAYSI-------- 712
SKL V DL++ + V ++ + +D MP G++ + + A I
Sbjct: 367 VASKLNPSVLDLLQELTSVTMLQASAKSKGLDEDFMPFGRIMQCSLDKAKDILLELEKLL 188
Query: 713 ---------LSEVQQAVSQGSSDSQILDLSNRFYTLIP 741
L+ V Q + + +I L+N FY L+P
Sbjct: 187 XTVNLQEKSLTTVPPEEYQANCE-KIATLTNEFYHLVP 77
>31070
Length = 428
Score = 35.0 bits (79), Expect = 0.15, Method: Composition-based stats.
Identities = 14/16 (87%), Positives = 16/16 (100%)
Frame = +2
Query: 982 TSLLYNEYIVYDIAQV 997
+SLLYNEYIVYD+AQV
Sbjct: 8 SSLLYNEYIVYDVAQV 55
>32072
Length = 272
Score = 33.1 bits (74), Expect = 0.52, Method: Compositional matrix adjust.
Identities = 17/48 (35%), Positives = 26/48 (54%)
Frame = +1
Query: 569 YYKLQLLEDDKENRYWIFRSWGRVGTVIGSNKLEQMPSKEDAIEHFMK 616
YY +Q+LED + Y +++ WGRVG +N + AI+ F K
Sbjct: 58 YYIIQVLEDTSKKAYHVWQRWGRVGYKGQTNLVNTGGDLNKAIDVFSK 201
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000325970 | hsapiens_gene_ensembl | Cell division
control protein 2 homolog (EC 2.7.11.22) (EC 2.7.11.23) (p34 protein
kinase) (Cyclin-dependent kinase 1) (CDK1).
[Source:Uniprot/SWISSPROT;Acc:P06493]
(240 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
01060 260 3e-70
14126 178 2e-45
32000 168 1e-42
24241 143 5e-35
01966 142 1e-34
03294 131 2e-31
01707 130 4e-31
01756 122 1e-28
29581 113 8e-26
04138 105 1e-23
20559 103 2e-23
04591 97 5e-21
23319 96 1e-20
12453 76 1e-14
18287 66 1e-11
26909 62 3e-10
28638 40 1e-09
18401 57 5e-09
01718 54 7e-08
03508 53 1e-07
18921 51 4e-07
15910 49 1e-06
06405 49 2e-06
00300 48 3e-06
11780 48 4e-06
16003 48 4e-06
01392 47 6e-06
13078 47 7e-06
13840 46 1e-05
17975 45 2e-05
22005 45 2e-05
13592 45 3e-05
09606 45 3e-05
19301 44 5e-05
05084 44 6e-05
32359 42 2e-04
26156 42 3e-04
12721 41 5e-04
16350 40 8e-04
02638 40 8e-04
20152 40 8e-04
00394 38 0.005
15549 37 0.010
31789 36 0.015
20773 35 0.037
03240 34 0.042
17644 34 0.054
14420 33 0.092
32357 33 0.12
38560 33 0.13
35032 32 0.20
15931 32 0.27
17253 32 0.28
21433 32 0.29
37602 31 0.56
20513 30 1.0
27546 30 1.2
28157 30 1.2
21210 28 2.7
17516 28 4.1
13305 28 4.5
17806 27 5.8
04852 27 6.2
26052 27 6.5
00392 27 8.5
>01060
Length = 1800
Score = 260 bits (664), Expect = 3e-70, Method: Compositional matrix adjust.
Identities = 138/295 (46%), Positives = 177/295 (60%), Gaps = 57/295 (19%)
Frame = +1
Query: 1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH 60
+ D T +KIGEGTYGVVYK RH+ TG+ +AMKKIRL E+GVPS+AIREI++L+ELRH
Sbjct: 70 LSDLTDFQKIGEGTYGVVYKCRHRATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELRH 249
Query: 61 PNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVK-----VVT------ 109
NIV L+DV+M+D RL+L+FEFLSMDLK Y+D P G +D LVK +VT
Sbjct: 250 TNIVCLEDVIMEDERLFLVFEFLSMDLKMYIDKFPEGVVLDRRLVKSYVFQIVTGIXFCH 429
Query: 110 ---LWYR--SPEVLL------------GSAR----------------------------- 123
+ +R P+ LL G AR
Sbjct: 430 QRRIVHRDLKPQNLLINHTGAIKIADFGMARTFALPVRAYTHEVVTLWYRAPEILMGASK 609
Query: 124 YSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNT 183
YSTPVD+WSIGTIFA++ + P+F GDSEIDQLF+IFR +GTP + WPE L +
Sbjct: 610 YSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKLPAFNGM 789
Query: 184 FPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLDNQIK 238
FP WK G L+ + +LD GLDL+ + L DPA+RIS K L H YF ++D +K
Sbjct: 790 FPLWKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYFLNVDTSVK 954
>14126
Length = 1265
Score = 178 bits (451), Expect = 2e-45, Method: Compositional matrix adjust.
Identities = 115/299 (38%), Positives = 153/299 (51%), Gaps = 65/299 (21%)
Frame = +3
Query: 2 EDYTKIEKIGEGTYGVVYKGRH-KTTGQVVAMKKIRLESEEEGVPSTAIREISLLKEL-- 58
+ Y ++ IG G YG VYK R + G+ VAMK+IRL + EEG+P AIREIS+LK+L
Sbjct: 189 QKYEEVAVIGNGAYGTVYKARDLRNQGEFVAMKRIRLNNTEEGMPMMAIREISMLKQLEQ 368
Query: 59 -RHPNIVSLQDVLM-----QDSRLYLIFEFLSMDLKKYLDSIP-PG-------------- 97
HPN+V L DV ++ RL L+FE++ DL YL P PG
Sbjct: 369 YEHPNVVRLLDVSHNTITDREIRLNLVFEYIEHDLATYLAKCPSPGLGPDRIKDLMLQLL 548
Query: 98 -----------------------------QYMDSSLVKV-----------VTLWYRSPEV 117
+ D L ++ VTLWYRSPEV
Sbjct: 549 NGVDFLHSNRIVHRDLKPQNLLISKDGRLKLADFGLARIYSFHMALTTVVVTLWYRSPEV 728
Query: 118 LLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESL 177
L+ A Y T VDIWS G IFAEL T++ LF G SE DQL +IF +G P WPE S+
Sbjct: 729 LM-QAEYGTSVDIWSCGCIFAELFTRRALFKGSSEFDQLKKIFEVIGLPPAGDWPEGVSV 905
Query: 178 QDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYF-NDLDN 235
++N+F P L + V +D DL+ KML++ +RIS + +L HPY +DLD+
Sbjct: 906 --HRNSFRPTPPVPLQTLVPEMDPQAKDLMEKMLVFKSGRRISSRESLLHPYLRDDLDS 1076
>32000
Length = 644
Score = 168 bits (426), Expect = 1e-42, Method: Compositional matrix adjust.
Identities = 77/128 (60%), Positives = 98/128 (76%)
Frame = -1
Query: 106 KVVTLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGT 165
+V+TLWYR+PE+LLG YS PVDIWS+G IF E+ T++ LF GDSEIDQL+RIFR LGT
Sbjct: 509 EVITLWYRAPEILLGCRFYSVPVDIWSLGCIFVEMMTRRALFPGDSEIDQLYRIFRTLGT 330
Query: 166 PNNEVWPEVESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMAL 225
P+ +VWP V L DYK TFPKW +L + V +L + GLDLL +ML Y+P +RIS + A+
Sbjct: 329 PDEKVWPGVSKLPDYKPTFPKWPLKNLET-VVSLSKVGLDLLKRMLTYNPNRRISARSAM 153
Query: 226 NHPYFNDL 233
HPYFND+
Sbjct: 152 RHPYFNDM 129
>24241
Length = 413
Score = 143 bits (361), Expect = 5e-35, Method: Compositional matrix adjust.
Identities = 66/105 (62%), Positives = 85/105 (80%), Gaps = 1/105 (0%)
Frame = -2
Query: 6 KIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPN-IV 64
++ KIGEGTYGVVYK RH+ TG+ +AMKKIRL E+GVPS+AIREI++L+ELRH +V
Sbjct: 331 RLSKIGEGTYGVVYKCRHRATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTQXLV 152
Query: 65 SLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKVVT 109
L+DV+M+D RL+L+FEFLSMDLK Y+D P G +D LVK+VT
Sbjct: 151 CLEDVIMEDERLFLVFEFLSMDLKMYIDKFPEGVVLDRRLVKIVT 17
>01966
Length = 1735
Score = 142 bits (358), Expect = 1e-34, Method: Compositional matrix adjust.
Identities = 62/119 (52%), Positives = 83/119 (69%)
Frame = -3
Query: 120 GSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQD 179
G+++YSTPVD+WSIGTIFA++ + P+F GDSEIDQLF+IFR +GTP + WPE L
Sbjct: 1187 GASKYSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKLPA 1008
Query: 180 YKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLDNQIK 238
+ FP WK G L+ + +LD GLDL+ + L DPA+RIS K L H YF ++D +K
Sbjct: 1007 FNGMFPLWKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYFLNVDTSVK 831
Score = 119 bits (298), Expect(2) = 1e-29, Method: Compositional matrix adjust.
Identities = 54/85 (63%), Positives = 69/85 (81%)
Frame = -1
Query: 22 RHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQDVLMQDSRLYLIFE 81
RH+ TG+ +AMKKIRL E+GVPS+AIREI++L+ELRH NIV L+DV+M+D RL+L+FE
Sbjct: 1651 RHRATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTNIVCLEDVIMEDERLFLVFE 1472
Query: 82 FLSMDLKKYLDSIPPGQYMDSSLVK 106
FLSMDLK Y+D P G +D LVK
Sbjct: 1471 FLSMDLKMYIDKFPEGVVLDRRLVK 1397
Score = 27.3 bits (59), Expect(2) = 1e-29, Method: Compositional matrix adjust.
Identities = 11/14 (78%), Positives = 13/14 (92%)
Frame = -2
Query: 6 KIEKIGEGTYGVVY 19
++ KIGEGTYGVVY
Sbjct: 1698 RLSKIGEGTYGVVY 1657
Score = 37.0 bits (84), Expect = 0.008, Method: Compositional matrix adjust.
Identities = 25/82 (30%), Positives = 37/82 (45%), Gaps = 3/82 (3%)
Frame = -1
Query: 106 KVVTLWYRSPEVLLGSARYSTPVDIWSIGTI--FAELATKKPL-FHGDSEIDQLFRIFRA 162
+VVTLWYR+PE+L+G STP W+ G + + + + PL ++ R +
Sbjct: 1228 EVVTLWYRAPEILMGPQ--STP-PXWTCGALEPSSPICSSGPLSSRATPKLTSFLRYSGS 1058
Query: 163 LGTPNNEVWPEVESLQDYKNTF 184
L N P S Q F
Sbjct: 1057 LALQRNRRGPSFTSCQHSMACF 992
>03294
Length = 1684
Score = 131 bits (330), Expect = 2e-31, Method: Compositional matrix adjust.
Identities = 58/112 (51%), Positives = 76/112 (67%)
Frame = -1
Query: 127 PVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNTFPK 186
PVD+WSIGTIFA++ + P+F GDSEIDQLF+IFR +GTP + WPE L + FP
Sbjct: 1675 PVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKLPAFNGMFPL 1496
Query: 187 WKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLDNQIK 238
WK G L+ + +LD GLDL+ + L DPA+RIS K L H YF ++D +K
Sbjct: 1495 WKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYFLNVDTSVK 1340
>01707
Length = 757
Score = 130 bits (328), Expect = 4e-31, Method: Compositional matrix adjust.
Identities = 80/220 (36%), Positives = 116/220 (52%), Gaps = 56/220 (25%)
Frame = +1
Query: 1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEG-VPSTAIREISLLKELR 59
ME Y KI KIGEG+YGVV+K R+K T Q+VA+KK +ESE++ + A+REI +LK+L+
Sbjct: 61 MEKYEKIGKIGEGSYGVVFKCRNKETSQLVAIKKF-VESEDDPLIKKIAMREIRMLKQLK 237
Query: 60 HPNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPG---------------------Q 98
HPN+V L +V + RL+L+F+++ L LD P G Q
Sbjct: 238 HPNLVRLIEVFRRKKRLHLVFDYVDHTLLNELDRYPRGLPEPMVKRIIYQTLLAVNFCHQ 417
Query: 99 Y----------------------MDSSLVKVVT------------LWYRSPEVLLGSARY 124
Y D +++T WYR+PE+L+G +Y
Sbjct: 418 YNTIHRDVKPENILITRQGQVKLCDFGFARILTGPGDEYTDYVATRWYRAPELLVGDTQY 597
Query: 125 STPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALG 164
PVD+W+IG +FAEL T + L+ G S++DQL I + LG
Sbjct: 598 GPPVDVWAIGCVFAELLTGQALWPGRSDVDQLHLIRKTLG 717
>01756
Length = 1858
Score = 122 bits (306), Expect = 1e-28, Method: Compositional matrix adjust.
Identities = 95/296 (32%), Positives = 137/296 (46%), Gaps = 69/296 (23%)
Frame = -3
Query: 4 YTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNI 63
Y K+ KIG+GT+G V+K R K T QVVAMKK+ +++E+EG P TA+REI +L+ L H N+
Sbjct: 1736 YEKLAKIGQGTFGEVFKARCKKTKQVVAMKKVLMDNEKEGFPITALREIKILQLLNHENV 1557
Query: 64 VSLQDVLMQ--------DSRLYLIFEFLSMDL----------------KKYLDSIPPGQY 99
V L ++ S YL+FEF DL K+ + + G Y
Sbjct: 1556 VDLIEICSTKATSANRYKSMFYLVFEFCEHDLAGLLSNMSVVFNLPEIKEVMKQLMNGLY 1377
Query: 100 ---------------------------MDSSLVKVVTLWYRSP---------------EV 117
D L + ++ R P E+
Sbjct: 1376 YIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRPPEL 1197
Query: 118 LLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESL 177
LLG YST +D W G I AE+ T+ P+ G +E +QL I + G+ EVWP VE L
Sbjct: 1196 LLGDRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQNQLTLITQLCGSITPEVWPGVERL 1017
Query: 178 QDYKN-TFPKWKPGSLASHVKNL--DENGLDLLSKMLIYDPAKRISGKMALNHPYF 230
+ Y + P+ + ++ D LDLL K+L DP KR++ AL+H +F
Sbjct: 1016 ELYNSLDLPQGNKRKVKERLRYYIKDAYALDLLDKLLALDPGKRVNSDEALSHDFF 849
>29581
Length = 1278
Score = 113 bits (282), Expect = 8e-26, Method: Compositional matrix adjust.
Identities = 76/246 (30%), Positives = 110/246 (44%), Gaps = 58/246 (23%)
Frame = -2
Query: 45 PSTAIREISLLKELRHPNIVSLQDVLMQDS--RLYLIFEFLSMDLKKYLDSIPPG----- 97
PS + L LRH NIV LQ+V++ S L+L+ E+ DL LD++P
Sbjct: 1223 PSVVCVRSTFLLNLRHQNIVQLQEVVVGKSLDSLFLVMEYCEQDLASLLDNMPAPFSESQ 1044
Query: 98 ------------QYM------------------DSSLVKV-------------------- 107
+Y+ D VK+
Sbjct: 1043 VKCIVLQLLKGLRYLHEAFIIHRDLKVSNLLMTDKGCVKIADFGLARNYGKPQKPMTPKV 864
Query: 108 VTLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPN 167
VTLWYR+PE+L GS +ST +D+WS G I EL KPL G S++ Q+ I LGTPN
Sbjct: 863 VTLWYRAPELLFGSKTHSTAIDMWSAGCILGELLGHKPLMPGRSDLQQIELIMELLGTPN 684
Query: 168 NEVWPEVESLQDYKNTFPKWKP-GSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALN 226
+ +WP L ++ K +P +L L E+G+ LL+ + +Y P KR + + L
Sbjct: 683 DTIWPGFSQLPAFEQFTLKKQPYNNLRHTFPWLSESGIRLLNGLFMYHPQKRATAEDCLE 504
Query: 227 HPYFND 232
H YF +
Sbjct: 503 HSYFKE 486
Score = 32.0 bits (71), Expect = 0.26, Method: Compositional matrix adjust.
Identities = 12/34 (35%), Positives = 23/34 (67%)
Frame = -1
Query: 28 QVVAMKKIRLESEEEGVPSTAIREISLLKELRHP 61
++VA+KK+R+ E G+P + +REI++ + P
Sbjct: 1275 EIVALKKMRMTGERYGIPISGLREINIFAQSATP 1174
>04138
Length = 800
Score = 105 bits (263), Expect = 1e-23, Method: Compositional matrix adjust.
Identities = 67/191 (35%), Positives = 101/191 (52%), Gaps = 10/191 (5%)
Frame = +1
Query: 50 REISLLKELRHPNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKVVT 109
R L ++++ NI+ + +++ + L F S++L++ P +Y + +VVT
Sbjct: 67 RNKILHRDMKAANILITKQGVLKLADFGLARAF-SVNLRQ------PNRYTN----RVVT 213
Query: 110 LWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNE 169
LWYR PE+LLG YST +D W G I AE+ T+ P+ G +E +QL I + G+ E
Sbjct: 214 LWYRPPELLLGDRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQNQLTLITQLCGSITPE 393
Query: 170 VWPEVESLQDYKNTFPKWKPGSLASHVKNL----------DENGLDLLSKMLIYDPAKRI 219
VWP V L Y G+LA+ KN+ D GLDL ++L DP++RI
Sbjct: 394 VWPGVTQLSMYHQI-----KGALAAGRKNIIRDRFARILKDPYGLDLFERLLKMDPSQRI 558
Query: 220 SGKMALNHPYF 230
S ALNH +F
Sbjct: 559 SADEALNHDFF 591
>20559
Length = 430
Score = 103 bits (256), Expect(2) = 2e-23, Method: Compositional matrix adjust.
Identities = 45/80 (56%), Positives = 65/80 (81%)
Frame = -2
Query: 1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH 60
M+ Y K+EKIGEGTYG V+K +++ T ++VA+K++RL+ ++EGVPS+A+REI LLKEL+H
Sbjct: 378 MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKH 199
Query: 61 PNIVSLQDVLMQDSRLYLIF 80
NIV L DVL + +L L+F
Sbjct: 198 RNIVRLHDVLHSERKLTLVF 139
Score = 23.1 bits (48), Expect(2) = 2e-23, Method: Compositional matrix adjust.
Identities = 8/15 (53%), Positives = 10/15 (66%)
Frame = -3
Query: 80 FEFLSMDLKKYLDSI 94
FE+ DLKKY D+
Sbjct: 140 FEYCDQDLKKYFDTC 96
>04591
Length = 1117
Score = 97.4 bits (241), Expect = 5e-21, Method: Compositional matrix adjust.
Identities = 53/128 (41%), Positives = 75/128 (58%), Gaps = 3/128 (2%)
Frame = -2
Query: 106 KVVTLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGT 165
+VVTLWYR PE+LLG Y +D+W +G I AE+ ++KPL G SE QL I G+
Sbjct: 720 RVVTLWYRPPELLLGEREYGPEIDMWGVGCIMAEMWSRKPLMQGRSEQHQLSLITDLCGS 541
Query: 166 PNNEVWPEVESLQDY-KNTFPKWKPGSLASHVKNLDEN--GLDLLSKMLIYDPAKRISGK 222
N EVWP V L+ Y K P+ KP + + +L +N G +L+ L DP +R++
Sbjct: 540 LNAEVWPGVTKLELYGKLDLPQGKPRKVKERMLDLLKNKEGAELIDIFLRLDPGQRMNCD 361
Query: 223 MALNHPYF 230
AL+H +F
Sbjct: 360 NALSHDFF 337
Score = 47.4 bits (111), Expect = 5e-06, Method: Compositional matrix adjust.
Identities = 24/62 (38%), Positives = 36/62 (58%), Gaps = 8/62 (12%)
Frame = -2
Query: 41 EEGVPSTAIREISLLKELRHPNIVSLQDVLMQD--------SRLYLIFEFLSMDLKKYLD 92
+EG P TA+REI +L++L H N+V LQ++ S YLIFE+ DL L+
Sbjct: 1101 KEGFPITALREIKILQQLEHENVVQLQEICHTQAGPYNRYKSTFYLIFEYCDYDLAGLLN 922
Query: 93 SI 94
++
Sbjct: 921 NL 916
>23319
Length = 2235
Score = 96.3 bits (238), Expect = 1e-20, Method: Compositional matrix adjust.
Identities = 51/118 (43%), Positives = 71/118 (60%), Gaps = 2/118 (1%)
Frame = +3
Query: 124 YSTPVDIWSIGTIFAELATK-KPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKN 182
YST +D+WS G IFAELA +PLF G+ + DQL RIF+ LGTP + WP + L +Y+
Sbjct: 27 YSTSIDMWSAGCIFAELANAGRPLFPGNDDDDQLKRIFKLLGTPTEDQWPGMTQLPNYR- 203
Query: 183 TFPKWKPGSLASH-VKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLDNQIKK 239
FP + + V L+ G DLL +L+ P+ R+S AL HPYF DL +++
Sbjct: 204 MFPMYHVTTTWQQVVPKLNSKGRDLLQCLLVCCPSDRMSADEALQHPYFADLPPLVRQ 377
>12453
Length = 680
Score = 75.9 bits (185), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 38/102 (37%), Positives = 57/102 (55%), Gaps = 1/102 (0%)
Frame = +3
Query: 133 IGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKN-TFPKWKPGS 191
+G IF E+A +PLF G + D+L IF+ LGTP + P + D+ P ++ +
Sbjct: 6 VGCIFYEMACGRPLFPGSTVEDELHLIFKTLGTPTEDSLPSISRNPDFLALNLPHYQGEA 185
Query: 192 LASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDL 233
L + LD +GLDLL+K L Y+ R+S +L H +FN L
Sbjct: 186 LITIAPRLDSDGLDLLAKFLKYNAKIRVSAADSLKHSFFNSL 311
>18287
Length = 678
Score = 66.2 bits (160), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 37/112 (33%), Positives = 60/112 (53%), Gaps = 3/112 (2%)
Frame = -3
Query: 124 YSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNE-VWPEVESLQDY-- 180
Y +DIWS+G IFAEL +++ LF + QL I +GTP E + E +++
Sbjct: 673 YDYSIDIWSVGCIFAELLSRRILFQAQGPVQQLDMIINLVGTPRPEDMERACEGARNHIL 494
Query: 181 KNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFND 232
F + +L + + + LL++MLI +P RIS + AL+HPY ++
Sbjct: 493 NQPFRRQNLLTLYNLSPHATHEAVRLLTRMLILNPKNRISAEEALSHPYLDE 338
>26909
Length = 394
Score = 61.6 bits (148), Expect = 3e-10, Method: Compositional matrix adjust.
Identities = 36/113 (31%), Positives = 52/113 (46%), Gaps = 18/113 (15%)
Frame = +2
Query: 136 IFAELATKKPLFHGDSE---------IDQLFRIFRALGTPNNEVWPEVESLQDYKNTFPK 186
IFAEL T +P+FH E DQL RIF +G P + W ++ + +++
Sbjct: 2 IFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFPQEKDWEDIRRMPEHQQLTKD 181
Query: 187 WKPGS---------LASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYF 230
+K S + H D LL K+L DP KRI+ + A+ PYF
Sbjct: 182 FKRSSYVNCNLMKYMEKHKVKADSKAFHLLQKLLTMDPVKRITSEQAMKDPYF 340
>28638
Length = 1458
Score = 40.4 bits (93), Expect(2) = 1e-09, Method: Compositional matrix adjust.
Identities = 18/35 (51%), Positives = 24/35 (68%)
Frame = -1
Query: 111 WYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKP 145
+YRSPEVLLG Y +D+WS+G I E+ T +P
Sbjct: 639 FYRSPEVLLG-VPYDLAIDMWSLGCILVEMHTGEP 538
Score = 38.9 bits (89), Expect(2) = 1e-09, Method: Compositional matrix adjust.
Identities = 33/126 (26%), Positives = 50/126 (39%), Gaps = 34/126 (26%)
Frame = -2
Query: 145 PLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNTFP-------------KWK-PG 190
PLF G +E DQ+ +I LG P + + + + Y + P K+K P
Sbjct: 539 PLFAGSNEFDQMMKIVEVLGVPPRHILDQAQKTRKYFDLLPDGTYAPKKPRDNKKYKSPS 360
Query: 191 SLASH-----------VKNLDENG---------LDLLSKMLIYDPAKRISGKMALNHPYF 230
S H + + E G DL+ +ML +DP RIS AL H +F
Sbjct: 359 SRKLHEVLGAEKGGPGGRRMGEPGHTVADYLKFKDLILRMLDFDPKTRISPYYALQHNFF 180
Query: 231 NDLDNQ 236
++
Sbjct: 179 RKTSDE 162
>18401
Length = 463
Score = 57.4 bits (137), Expect = 5e-09, Method: Compositional matrix adjust.
Identities = 50/147 (34%), Positives = 68/147 (46%), Gaps = 22/147 (14%)
Frame = -3
Query: 107 VVTLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALG-- 164
V T YR+PEV+L +S P D+WS+G I EL T LF + L + R LG
Sbjct: 449 VSTRHYRAPEVILELG-WSHPCDVWSVGCIMFELYTGYTLFQTHDNKEHLAMMERILGSL 273
Query: 165 -------TPNNEVW-------PEVESLQDY--KNTFPKWKPGSLASHVK---NLDENGL- 204
T + + PE S+ Y +NT P L +VK N D L
Sbjct: 272 PYRMAKKTKKQKYFHHGRLDVPERSSMARYVRENTKP------LLRYVKDRENKDHQQLF 111
Query: 205 DLLSKMLIYDPAKRISGKMALNHPYFN 231
DL+ K+L Y+ + R S AL HP+F+
Sbjct: 110 DLMKKLLAYEASSRYSLLQALQHPFFS 30
>01718
Length = 959
Score = 53.5 bits (127), Expect = 7e-08, Method: Compositional matrix adjust.
Identities = 30/93 (32%), Positives = 55/93 (59%), Gaps = 1/93 (1%)
Frame = +3
Query: 1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH 60
++D+ EKIG G + V+K H+ TGQV+A+K + S + +RE+ LL L+H
Sbjct: 147 LDDFI-CEKIGAGFFSEVFKVTHRITGQVMALKMNTMTSNRHNM----LREVQLLNRLQH 311
Query: 61 PNIVSLQDVLMQDSRLYLIFEFL-SMDLKKYLD 92
NI+ V + + +L+ + E++ S +L++ L+
Sbjct: 312 ANILRFMGVCVHEGQLHALTEYIPSGNLEQLLE 410
>03508
Length = 1463
Score = 52.8 bits (125), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 35/114 (30%), Positives = 55/114 (48%), Gaps = 14/114 (12%)
Frame = +2
Query: 131 WSIGTIFAEL----ATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQ-DYKNTF- 184
W+ G A L + K P FHG DQL RI + LGT ++++ +E Q D F
Sbjct: 1118 WTCGVWAACLPA*SSGKSPFFHGHDNYDQLVRIAKVLGT--DDLYGYIEKYQIDLDPRFN 1291
Query: 185 --------PKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYF 230
+W+ + + + LD L K+L YD +R++ + A++HPYF
Sbjct: 1292 DILGRHSRKRWERFVHSENQHLISPEALDFLDKLLRYDHNERLTAREAMDHPYF 1453
Score = 38.5 bits (88), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 14/40 (35%), Positives = 26/40 (65%)
Frame = +1
Query: 105 VKVVTLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKK 144
V+V + +++ PE+LL Y +D+WS+G +FA + +K
Sbjct: 1048 VRVASRYFKGPELLLDYQMYDYSLDMWSLGCMFASMIFRK 1167
>18921
Length = 697
Score = 51.2 bits (121), Expect = 4e-07, Method: Compositional matrix adjust.
Identities = 24/76 (31%), Positives = 49/76 (64%)
Frame = +2
Query: 9 KIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQD 68
K+GEG+YG V+K HK TGQV+A+K++ ++++ + + I+EIS++++ IV
Sbjct: 50 KLGEGSYGSVFKSLHKETGQVLAIKQVPVDTDLQEI----IKEISIMQQCDSKYIVKYYG 217
Query: 69 VLMQDSRLYLIFEFLS 84
+++ L+++ E+
Sbjct: 218 SYFKNTDLWIVMEYCG 265
>15910
Length = 1361
Score = 49.3 bits (116), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 33/129 (25%), Positives = 54/129 (41%)
Frame = +2
Query: 112 YRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVW 171
Y +PEVL G +Y+ VD+WS+G I L F ++E + +I + + E W
Sbjct: 668 YCAPEVLKGD-KYTPSVDMWSVGVIAYILLCGYEPFFAENEFEMYRKIIKGEYKFDEEYW 844
Query: 172 PEVESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFN 231
E+ EN D++ K+L+ DP KR++ AL P+
Sbjct: 845 SEI-------------------------SENAKDVVRKLLVIDPKKRLTATEALRLPWVK 949
Query: 232 DLDNQIKKM 240
+ + M
Sbjct: 950 GVATKTTNM 976
>06405
Length = 1965
Score = 48.5 bits (114), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 27/86 (31%), Positives = 50/86 (58%), Gaps = 1/86 (1%)
Frame = +1
Query: 9 KIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQD 68
++G G YG VY+ K ++VA+K ++ E+ + + E +++KE++HPN+V L
Sbjct: 280 RLGGGQYGDVYEAMWKRYNKIVAVKTLK---EDTMALNDFLEEAAIMKEMKHPNLVQLLG 450
Query: 69 VLMQDSRLYLIFEFLSM-DLKKYLDS 93
V ++ Y++ EF+ +L YL S
Sbjct: 451 VCTREPPFYIVTEFMPHGNLLDYLRS 528
>00300
Length = 2318
Score = 48.1 bits (113), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 54/279 (19%), Positives = 100/279 (35%), Gaps = 58/279 (20%)
Frame = -1
Query: 9 KIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQD 68
KIGEG +G VY + +TG+++A+K+++ + + EI + + ++H N+V
Sbjct: 1637 KIGEGQFGKVYTAVNMSTGELMALKEMKFQPNDLQQLREMCDEIKIFEGIQHENLVKYYG 1458
Query: 69 VLMQDSRLYLIFEFL---------SMDLKKYL---------------------------- 91
V + + + E+ M L +YL
Sbjct: 1457 VEVHKDEMLMFMEYCDTGTIEEAAKMGLPEYLIRRYTREIVLAVNHLHENSIVHRDIKGA 1278
Query: 92 -------DSIPPGQYMDSSLVKVVTLWYRSPEVLLGSARYSTP--------------VDI 130
+ G + S +K T L+G+ Y P DI
Sbjct: 1277 NIFLTSNGHVKLGDFGCSVKLKSHTTMPGEFHNLVGTTAYMAPEVFTQNDQGGYGRAADI 1098
Query: 131 WSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNTFPKWKPG 190
WS+G + E+AT K +H ++D ++I +G + P+ S++
Sbjct: 1097 WSLGCVVIEMATGKRPWH---DLDNNYQIMYKVGIGHKPAVPDSLSVE------------ 963
Query: 191 SLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPY 229
G L ++ +DPA+R L+H +
Sbjct: 962 ------------GKHFLDLIMCHDPAQRALASQLLDHTF 882
>11780
Length = 1713
Score = 47.8 bits (112), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 31/87 (35%), Positives = 56/87 (64%), Gaps = 1/87 (1%)
Frame = +3
Query: 8 EKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQ 67
E IG+G +G VYKG ++ GQ VA+K+++ + E + ++E S++ LRH N+V L
Sbjct: 615 EAIGKGDFGDVYKGMYR--GQPVAIKQLKDKDRGE---QSFLQEASVMTSLRHDNLVRLI 779
Query: 68 DVLMQDSRLYLIFEFLSM-DLKKYLDS 93
V++ ++ ++L+ EF+ +L +YL S
Sbjct: 780 GVVLGET-IFLVTEFMGKGNLVEYLRS 857
>16003
Length = 926
Score = 47.8 bits (112), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 33/88 (37%), Positives = 46/88 (52%)
Frame = -1
Query: 145 PLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNTFPKWKPGSLASHVKNLDENGL 204
P GD+++DQL +IF LGTP WP V SL DY F + L ++ L
Sbjct: 911 PFLPGDTDLDQLGKIFNMLGTPTETEWPAVTSLPDYIQ-FKHCQKQPLKEIFTAAGDDLL 735
Query: 205 DLLSKMLIYDPAKRISGKMALNHPYFND 232
+LL K+L +P R + AL PYF++
Sbjct: 734 ELLDKLLAMNPLHRCTATQALKMPYFSN 651
>01392
Length = 1806
Score = 47.4 bits (111), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 42/165 (25%), Positives = 69/165 (41%), Gaps = 21/165 (12%)
Frame = -1
Query: 87 LKKYLDSIPPGQYMDSSLVKVVTL---WYRSPEVL--LGSARYSTP-------------- 127
L ++LD + P + D L ++ ++PE+L +GSA Y P
Sbjct: 1695 LCEHLDDVVPVKICDFDLASGISCDGDGTKTPELLTPVGSAEYMAPEVVDAWVGDSFSYD 1516
Query: 128 --VDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNTFP 185
D+WS+G I + P F+G D + A + ++ S+QD FP
Sbjct: 1515 KRCDLWSLGIILYIMLCGYPPFYGQCGEDCGWNRGEACHDCQDMLF---NSIQDGHYKFP 1345
Query: 186 KWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYF 230
+ S++S K DL+ +L+ +P KR S L HP+
Sbjct: 1344 SQEWTSISSSAK-------DLIRHLLVREPRKRYSAADVLKHPWI 1231
>13078
Length = 773
Score = 47.0 bits (110), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 36/126 (28%), Positives = 56/126 (44%), Gaps = 16/126 (12%)
Frame = -1
Query: 124 YSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNT 183
+S P D+WSIG I EL T LF + L + R LG+ + + + + + +
Sbjct: 746 WSQPCDVWSIGCIMFELYTGYTLFQTHDNKEHLAMMERILGSLPYRMAKKTKKQKYFYHG 567
Query: 184 FPKWKPGSLAS------------HVKNLD----ENGLDLLSKMLIYDPAKRISGKMALNH 227
W S A +VK+ D + DL+ KML Y+ + R S + A+ H
Sbjct: 566 RLDWDEKSSAGRYVRDNVKPLRRYVKDPDNEDHQQLFDLMDKMLSYEVSTRYSLRQAMRH 387
Query: 228 PYFNDL 233
P+F L
Sbjct: 386 PFFRKL 369
>13840
Length = 446
Score = 46.2 bits (108), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 27/89 (30%), Positives = 42/89 (47%)
Frame = -1
Query: 2 EDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHP 61
ED + +IG G YG V K RHK T V+A+K+IR EE + +++ P
Sbjct: 395 EDMQDMGEIGRGNYGTVNKMRHKITSTVMAVKRIRSTVEEREQKQLLMDLDVVMRSNNCP 216
Query: 62 NIVSLQDVLMQDSRLYLIFEFLSMDLKKY 90
IV L ++ ++ E + L K+
Sbjct: 215 FIVQFYGALFKEGDCWICMELMETSLDKF 129
>17975
Length = 449
Score = 45.4 bits (106), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 25/68 (36%), Positives = 39/68 (57%)
Frame = +3
Query: 15 YGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQDVLMQDS 74
+ VV RH TG+ VA+K I +E S +E+ +K ++HPN+V L +V+ +
Sbjct: 6 FAVVKLARHVFTGEKVAVKVIDKTKLDEVSRSHLFQEVRCMKLVQHPNVVRLYEVIDTQT 185
Query: 75 RLYLIFEF 82
+LYLI E
Sbjct: 186KLYLILEL 209
>22005
Length = 873
Score = 45.4 bits (106), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 34/101 (33%), Positives = 47/101 (46%), Gaps = 11/101 (10%)
Frame = +1
Query: 10 IGEGTYGVVYK----GRHKTTGQVVAMK------KIRLESEEEGVPSTAIREISLLKELR 59
IG+G +G V K G G+++ K K+ E E + S RE SL+ +
Sbjct: 7 IGQGAFGRVSKLKFLGLASLVGELIPEKRP*LL*KMLKEDASEDLQSDFEREASLMADFD 186
Query: 60 HPNIVSLQDVLMQDSRLYLIFEFLSM-DLKKYLDSIPPGQY 99
HPNIV L V + L+FEF+S DL +L P Y
Sbjct: 187 HPNIVKLLGVCAIGKPMCLLFEFMSKGDLNDFLRLCSPENY 309
>13592
Length = 980
Score = 45.1 bits (105), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 22/76 (28%), Positives = 40/76 (52%)
Frame = +2
Query: 9 KIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQD 68
KIG+G +G VY + TG+++AMK+I ++ E E+ +L+ ++H N+V
Sbjct: 5 KIGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETRALKNVAEELKILEGIKHKNLVRYYG 184
Query: 69 VLMQDSRLYLIFEFLS 84
+ + L + E S
Sbjct: 185IEVHREELLIFMELCS 232
Score = 36.6 bits (83), Expect = 0.009, Method: Compositional matrix adjust.
Identities = 30/117 (25%), Positives = 47/117 (40%), Gaps = 3/117 (2%)
Frame = +2
Query: 107 VVTLWYRSPEVLL--GSARYSTPVDIWSIGTIFAELAT-KKPLFHGDSEIDQLFRIFRAL 163
V T Y +PEV S + DIWS+G + E+A+ K+P ++ D F+I +
Sbjct: 476 VGTQAYMAPEVFTKTNSDGHGRLADIWSVGCVVVEMASGKRPW----AQFDSNFQIMFKV 643
Query: 164 GTPNNEVWPEVESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRIS 220
G PE +L + G D + L +DP +R+S
Sbjct: 644 GMGEKPQAPE------------------------SLSQEGHDFIDHCLQHDPKQRLS 742
>09606
Length = 1300
Score = 44.7 bits (104), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 22/84 (26%), Positives = 42/84 (50%)
Frame = -3
Query: 1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH 60
ME++ E++G+G + ++YKGR K T VA+ I E+ + + ++ H
Sbjct: 1118 MENFVLYEELGKGEHSIIYKGRRKGTINFVAIHCI-----EKCKRPEVTNTVRMTHDISH 954
Query: 61 PNIVSLQDVLMQDSRLYLIFEFLS 84
PN+V + + L+L+ E +
Sbjct: 953 PNVVQFHEWYETSNHLWLVVELCT 882
>19301
Length = 712
Score = 44.3 bits (103), Expect = 5e-05, Method: Compositional matrix adjust.
Identities = 33/107 (30%), Positives = 50/107 (46%), Gaps = 4/107 (3%)
Frame = +2
Query: 1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH 60
E T +E +G G G V+ G K + VA+KK+R + T IR L++L H
Sbjct: 302 FESITDLEWLGSGAQGAVFLG--KLCAEEVAVKKVR------DIKETDIRN---LRKLNH 448
Query: 61 PNIVSLQDVLMQDSRLYLIFEFLS----MDLKKYLDSIPPGQYMDSS 103
PNI+S + V Q +I E+ ++ + IPP +D S
Sbjct: 449 PNIISFKGVCTQAPCYCIIMEYCPYGQLYEVLRDGKEIPPALVLDWS 589
>05084
Length = 1324
Score = 43.9 bits (102), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 30/95 (31%), Positives = 50/95 (52%), Gaps = 3/95 (3%)
Frame = +2
Query: 149 GDSEIDQLFRIFRALGTPNNEVWPEVE-SLQDYKNTFPKWK--PGSLASHVKNLDENGLD 205
GDS +DQL I + LGTP E E+ + ++K FP+ K P + + E +
Sbjct: 8 GDSGVDQLVEIIKVLGTPTREQIREMNPNYSEFK--FPQIKAHPWTKVFRPRTPPE-AIQ 178
Query: 206 LLSKMLIYDPAKRISGKMALNHPYFNDLDNQIKKM 240
L+S++L Y P+ RI A H +F++L + ++
Sbjct: 179 LVSRLLEYTPSARIQPMEACAHAFFDELRDPASRL 283
>32359
Length = 928
Score = 42.4 bits (98), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 22/64 (34%), Positives = 39/64 (60%)
Frame = -1
Query: 4 YTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNI 63
YT + IG G++GVVY+ + T ++VA+KK+ + + RE+ ++++L H NI
Sbjct: 424 YTDAKVIGNGSFGVVYQAKLVDTSELVAIKKVLQDKRFKN------RELQIMRKLEHQNI 263
Query: 64 VSLQ 67
V L+
Sbjct: 262 VKLK 251
>26156
Length = 479
Score = 41.6 bits (96), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 23/86 (26%), Positives = 43/86 (50%), Gaps = 2/86 (2%)
Frame = -1
Query: 1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLE--SEEEGVPSTAIREISLLKEL 58
+ D+ + IG G+Y V + HK T ++ AMK I+ E +++E + +
Sbjct: 392 LTDFLLLRVIGRGSYAKVLQVEHKRTKRIYAMKVIKKELVNDDEDIDWVQTEKHVFETAT 213
Query: 59 RHPNIVSLQDVLMQDSRLYLIFEFLS 84
+P +V L +SRL+ + EF++
Sbjct: 212 NYPFLVGLHSCFQSESRLFFVIEFVN 135
>12721
Length = 821
Score = 40.8 bits (94), Expect = 5e-04, Method: Compositional matrix adjust.
Identities = 21/75 (28%), Positives = 43/75 (57%)
Frame = +1
Query: 9 KIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQD 68
KIGEG+ G+V + G+ +A+KK+ L ++ E+ ++++ HPNIV + +
Sbjct: 109 KIGEGSTGIVCIATSRD-GRQMAVKKMDLRKQQRR--ELLFNEVVVMRDYHHPNIVEMYN 279
Query: 69 VLMQDSRLYLIFEFL 83
+ + L+++ EF+
Sbjct: 280 SYLVNDELWVVMEFM 324
Score = 32.3 bits (72), Expect = 0.17, Method: Compositional matrix adjust.
Identities = 17/53 (32%), Positives = 28/53 (52%)
Frame = +1
Query: 107 VVTLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRI 159
V T ++ +PEV+ Y VDIWS+G + E+ +P F + + + RI
Sbjct: 556 VGTPYWMAPEVI-SRLPYGPEVDIWSLGIMVMEMIDAEPPFFNEPPLQAMRRI 711
>16350
Length = 1108
Score = 40.0 bits (92), Expect = 8e-04, Method: Compositional matrix adjust.
Identities = 21/41 (51%), Positives = 24/41 (58%)
Frame = +2
Query: 107 VVTLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLF 147
+ T YR EVL+G A Y TP DIWS + ELAT LF
Sbjct: 413 IQTRQYRCLEVLIG-AGYGTPADIWSTACMAFELATGDYLF 532
Score = 30.0 bits (66), Expect = 0.98, Method: Compositional matrix adjust.
Identities = 10/27 (37%), Positives = 16/27 (59%)
Frame = +3
Query: 205 DLLSKMLIYDPAKRISGKMALNHPYFN 231
D L+ ML +DP +R + +L HP+
Sbjct: 762 DFLAPMLEFDPEQRATAAQSLQHPWLK 842
>02638
Length = 1490
Score = 40.0 bits (92), Expect = 8e-04, Method: Compositional matrix adjust.
Identities = 31/123 (25%), Positives = 49/123 (39%)
Frame = +1
Query: 109 TLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNN 168
T+ + +PEVL G + Y D+WS+G + E+ T +P ++ + L IF+ + +
Sbjct: 25 TIAFMAPEVLRGES-YGRACDVWSVGCVMIEMCTCRPPWNSHDISNHLALIFKIASSVDP 201
Query: 169 EVWPEVESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHP 228
PE N+ DL+ + L D R S K L HP
Sbjct: 202 PPIPE------------------------NMSPPVRDLMLRCLEQDSDFRPSAKDLLMHP 309
Query: 229 YFN 231
F
Sbjct: 310 LFT 318
>20152
Length = 445
Score = 40.0 bits (92), Expect = 8e-04, Method: Compositional matrix adjust.
Identities = 31/120 (25%), Positives = 46/120 (38%)
Frame = +1
Query: 115 PEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEV 174
PE+LLG + + VD+WS+G I L + F ++ + L I
Sbjct: 1 PEILLGDSYDAPAVDVWSLGVILYMLVVGEAPFQEANDSETLTMIM-------------- 138
Query: 175 ESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLD 234
D + P ++ DL+ KML +P R S L HP+ ND D
Sbjct: 139 ----DCRYQIP-----------PHISHKCQDLIEKMLQREPVDRASLPHILAHPWLNDGD 273
>00394
Length = 548
Score = 37.7 bits (86), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 21/60 (35%), Positives = 31/60 (51%)
Frame = -2
Query: 9 KIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQD 68
+IG G++ VYKG G VA +++ + + E +LKEL+HPNIV D
Sbjct: 277 EIGRGSFKTVYKGLDTELGVAVAWCELQDKKWNKAERQRFKEEAEMLKELQHPNIVRFFD 98
>15549
Length = 470
Score = 36.6 bits (83), Expect = 0.010, Method: Compositional matrix adjust.
Identities = 14/39 (35%), Positives = 28/39 (71%)
Frame = -1
Query: 2 EDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESE 40
+++ IE++G+G YG+V++ ++K Q A+K+I L S+
Sbjct: 218 DEFECIEQMGKGGYGIVFRAKNKVDEQEYAVKRIALPSD 102
>31789
Length = 676
Score = 35.8 bits (81), Expect = 0.015, Method: Compositional matrix adjust.
Identities = 21/60 (35%), Positives = 31/60 (51%)
Frame = +2
Query: 9 KIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQD 68
+IG G++ VYKG G VA +++ + + E +LKEL+HPNIV D
Sbjct: 341 EIGRGSFKTVYKGLDTELGVAVAWCELQDKKWNKTERQRFKEEAEMLKELQHPNIVRFFD 520
>20773
Length = 391
Score = 34.7 bits (78), Expect = 0.037, Method: Compositional matrix adjust.
Identities = 11/35 (31%), Positives = 25/35 (71%)
Frame = -1
Query: 195 HVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPY 229
H + ++ +L+ ++L YDP++R++ +AL+HP+
Sbjct: 334 HTTVVTQHFYNLVQRLLTYDPSQRLTPDLALSHPF 230
>03240
Length = 1683
Score = 34.3 bits (77), Expect = 0.042, Method: Compositional matrix adjust.
Identities = 14/48 (29%), Positives = 26/48 (54%)
Frame = -3
Query: 112 YRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRI 159
Y +PEVL Y++ D WS+G I E+ P F+ ++ + +++
Sbjct: 661 YIAPEVLSRLGGYTSVCDWWSVGVILFEMLVGHPPFYANTPAETQYKV 518
>17644
Length = 463
Score = 33.9 bits (76), Expect = 0.054, Method: Compositional matrix adjust.
Identities = 11/35 (31%), Positives = 24/35 (68%)
Frame = +3
Query: 195 HVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPY 229
H + ++ BL+ ++L YDP++R++ +AL+HP+
Sbjct: 57 HTTVVTQHFYBLVQRLLTYDPSQRLTPDLALSHPF 161
>14420
Length = 528
Score = 33.1 bits (74), Expect = 0.092, Method: Compositional matrix adjust.
Identities = 29/116 (25%), Positives = 54/116 (46%)
Frame = +2
Query: 41 EEGVPSTAIREISLLKELRHPNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYM 100
+EG + RE E H N V +D+ D+ L + + + + + P Q
Sbjct: 191 DEGQIAAVCRECLQALEFLHENQVIHRDI-KSDNILLGMDGSVKLTDFGFCAQLSPEQSK 367
Query: 101 DSSLVKVVTLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQL 156
S++V T ++ +PEV+ +Y VDIWS+G + E+ +P + ++ + L
Sbjct: 368 RSTMVG--TPYWMAPEVVT-RKQYGPTVDIWSLGVMCIEMIEGEPPYLNENPLRAL 526
Score = 30.0 bits (66), Expect = 0.89, Method: Compositional matrix adjust.
Identities = 13/36 (36%), Positives = 24/36 (66%)
Frame = +2
Query: 49 IREISLLKELRHPNIVSLQDVLMQDSRLYLIFEFLS 84
I EI +++E ++PNIV+ D + L+++ EFL+
Sbjct: 44 INEILVMRENQNPNIVNYLDSYLVGEELWVVMEFLA 151
>32357
Length = 625
Score = 32.7 bits (73), Expect = 0.12, Method: Compositional matrix adjust.
Identities = 14/30 (46%), Positives = 22/30 (73%)
Frame = -2
Query: 4 YTKIEKIGEGTYGVVYKGRHKTTGQVVAMK 33
Y ++KIG G++G +Y G H T+G+ VA+K
Sbjct: 432 YRLMKKIGSGSFGEIYLGVHNTSGEEVAVK 343
>38560
Length = 479
Score = 32.7 bits (73), Expect = 0.13, Method: Compositional matrix adjust.
Identities = 31/121 (25%), Positives = 48/121 (39%), Gaps = 1/121 (0%)
Frame = -3
Query: 112 YRSPEVLLGSARYSTPVDIWSIGT-IFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEV 170
Y +PE++ G + DIWS+G ++A L P D + L
Sbjct: 387 YAAPELISGLEYLGSEADIWSMGVLLYALLCGYLPF--DDEKXSHL-------------- 256
Query: 171 WPEVESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYF 230
+ Q K+ P+W L E+ LL ML DP+ RI+ + L+H +
Sbjct: 255 ---*QKNQKRKDEVPEW-----------LSEDTTKLLEGMLQTDPSHRITIRRLLDHHWL 118
Query: 231 N 231
N
Sbjct: 117 N 115
>35032
Length = 465
Score = 32.0 bits (71), Expect = 0.20, Method: Compositional matrix adjust.
Identities = 12/27 (44%), Positives = 19/27 (70%)
Frame = +3
Query: 204 LDLLSKMLIYDPAKRISGKMALNHPYF 230
DL+ ++L YDP+KR++ AL HP+
Sbjct: 144 FDLVKRLLNYDPSKRLTPXXALAHPFL 224
>15931
Length = 447
Score = 31.6 bits (70), Expect = 0.27, Method: Compositional matrix adjust.
Identities = 13/30 (43%), Positives = 19/30 (63%)
Frame = +1
Query: 204 LDLLSKMLIYDPAKRISGKMALNHPYFNDL 233
DL+ KML Y+ + R S + A+ HP+F L
Sbjct: 76 FDLMDKMLSYEVSTRYSLRQAMRHPFFRKL 165
>17253
Length = 483
Score = 31.6 bits (70), Expect = 0.28, Method: Compositional matrix adjust.
Identities = 18/63 (28%), Positives = 31/63 (49%), Gaps = 2/63 (3%)
Frame = -1
Query: 38 ESEEEGVPSTAIREISLLKEL-RHPNIVSLQDVLMQDSRLYLIFEFLSM-DLKKYLDSIP 95
E+ + S +RE+S++++L RHPN+VS ++ EF DL +L
Sbjct: 438 EAATDAEKSEFLRELSIMRKLPRHPNVVSFMGCCTMSDPALILMEFCCHGDLLSFLRKRR 259
Query: 96 PGQ 98
P +
Sbjct: 258 PDR 250
>21433
Length = 590
Score = 31.6 bits (70), Expect = 0.29, Method: Compositional matrix adjust.
Identities = 26/86 (30%), Positives = 36/86 (41%)
Frame = +3
Query: 50 REISLLKELRHPNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKVVT 109
REI + LRH NI+ + +R+YLI EF P G+ L K +
Sbjct: 15 REIEIQSHLRHDNILRMFGYFHDKTRVYLILEF-----------APKGE-----LYKELQ 146
Query: 110 LWYRSPEVLLGSARYSTPVDIWSIGT 135
++ E + S PV WSI T
Sbjct: 147 RCHKFDENEQHAIYTSCPVP-WSIAT 221
>37602
Length = 804
Score = 30.8 bits (68), Expect = 0.56, Method: Compositional matrix adjust.
Identities = 12/30 (40%), Positives = 19/30 (63%)
Frame = -2
Query: 1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVV 30
++D+ I+++G GTYG VYK + T G
Sbjct: 512 LDDFELIQRVGSGTYGDVYKAKA*TQGACC 423
>20513
Length = 405
Score = 29.6 bits (65), Expect = 1.0, Method: Compositional matrix adjust.
Identities = 10/25 (40%), Positives = 16/25 (64%)
Frame = -1
Query: 205 DLLSKMLIYDPAKRISGKMALNHPY 229
D L+ ML +DP +R + +L HP+
Sbjct: 282 DFLAPMLEFDPEQRATAAQSLQHPW 208
>27546
Length = 426
Score = 29.6 bits (65), Expect = 1.2, Method: Compositional matrix adjust.
Identities = 9/33 (27%), Positives = 20/33 (60%)
Frame = -1
Query: 50 REISLLKELRHPNIVSLQDVLMQDSRLYLIFEF 82
RE+ +L L HPNI+ + +L + ++++ +
Sbjct: 333 RELEILTRLDHPNIIQIHSILQRGPKIFIFMRY 235
>28157
Length = 400
Score = 29.6 bits (65), Expect = 1.2, Method: Compositional matrix adjust.
Identities = 19/53 (35%), Positives = 31/53 (58%)
Frame = +3
Query: 30 VAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQDVLMQDSRLYLIFEF 82
VA+K R+ESE+E + ++E+ L + HPNIV L +D + L+ E+
Sbjct: 9 VAVK--RIESEQE--KKSFMQELKQLSRVSHPNIVCLYGAC-RDHPVCLVMEY 152
>21210
Length = 518
Score = 28.5 bits (62), Expect = 2.7, Method: Compositional matrix adjust.
Identities = 19/57 (33%), Positives = 27/57 (47%), Gaps = 4/57 (7%)
Frame = +3
Query: 112 YRSPEVL---LGSARYSTPVDIWSIGTIFAELATKK-PLFHGDSEIDQLFRIFRALG 164
Y +PE + S Y D+WS+G ELAT + P S DQL ++ R +
Sbjct: 18 YMAPERIDPRASSHGYDVRSDVWSLGITLMELATGRFPYRKWVSIFDQLQQVVRGVA 188
>17516
Length = 453
Score = 27.7 bits (60), Expect = 4.1, Method: Compositional matrix adjust.
Identities = 12/29 (41%), Positives = 17/29 (58%)
Frame = -3
Query: 112 YRSPEVLLGSARYSTPVDIWSIGTIFAEL 140
Y +PEVLL +Y D++S+ I EL
Sbjct: 421 YMAPEVLLQKGQYDMKADVYSLAIILWEL 335
>13305
Length = 549
Score = 27.7 bits (60), Expect = 4.5, Method: Compositional matrix adjust.
Identities = 11/38 (28%), Positives = 19/38 (50%)
Frame = +2
Query: 124 YSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFR 161
Y+T D+WS G + E+ T + ++ QLF +
Sbjct: 56 YTTQSDVWSFGVVLWEIFTLGGTPYSSTDTQQLFAFLK 169
>17806
Length = 433
Score = 27.3 bits (59), Expect = 5.8, Method: Compositional matrix adjust.
Identities = 16/51 (31%), Positives = 29/51 (56%), Gaps = 1/51 (1%)
Frame = +1
Query: 51 EISLLKELRHPNIVSLQDVLMQDSRLYLIFEFLSM-DLKKYLDSIPPGQYM 100
E++ +EL HPNIV L + + + ++ E ++ +LK+YL + Q M
Sbjct: 208 EVAPFRELDHPNIVRLLGQCTEMNPMLMLMECAALGNLKQYLRNHRHQQAM 360
>04852
Length = 1462
Score = 27.3 bits (59), Expect = 6.2, Method: Compositional matrix adjust.
Identities = 11/29 (37%), Positives = 17/29 (58%)
Frame = +1
Query: 112 YRSPEVLLGSARYSTPVDIWSIGTIFAEL 140
+ +PE L RY+T D+WS G + E+
Sbjct: 520 WMAPEALF-DMRYTTKSDVWSFGVVLWEI 603
>26052
Length = 562
Score = 26.9 bits (58), Expect = 6.5, Method: Compositional matrix adjust.
Identities = 11/27 (40%), Positives = 19/27 (70%)
Frame = -1
Query: 10 IGEGTYGVVYKGRHKTTGQVVAMKKIR 36
+G G++G V +HK TG+ +A+K I+
Sbjct: 367 LGVGSFGKVMALQHKDTGETLAVKNIQ 287
>00392
Length = 668
Score = 26.6 bits (57), Expect = 8.5, Method: Compositional matrix adjust.
Identities = 30/113 (26%), Positives = 45/113 (39%), Gaps = 6/113 (5%)
Frame = +3
Query: 51 EISLLKELRHPNIVSLQDVLMQDSR-----LYLIFEFL-SMDLKKYLDSIPPGQYMDSSL 104
E +LKEL+HPNIV D + + + L+ E + S LK YL
Sbjct: 81 EAEMLKELQHPNIVRFFDYWEEHNHRNRKVIILVTELMTSGTLKTYLKRFKKPN------ 242
Query: 105 VKVVTLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLF 157
VK++ W R +VL G ++ P+ H D + D +F
Sbjct: 243 VKILKNWCR--QVLKG---------------LYFLHTRTPPVIHRDLKCDNIF 350
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000362915 | hsapiens_gene_ensembl | Cell division
control protein 2 homolog (EC 2.7.11.22) (EC 2.7.11.23) (p34 protein
kinase) (Cyclin-dependent kinase 1) (CDK1).
[Source:Uniprot/SWISSPROT;Acc:P06493]
(240 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
01060 260 3e-70
14126 178 2e-45
32000 168 1e-42
24241 143 5e-35
01966 142 1e-34
03294 131 2e-31
01707 130 4e-31
01756 122 1e-28
29581 113 8e-26
04138 105 1e-23
20559 103 2e-23
04591 97 5e-21
23319 96 1e-20
12453 76 1e-14
18287 66 1e-11
26909 62 3e-10
28638 40 1e-09
18401 57 5e-09
01718 54 7e-08
03508 53 1e-07
18921 51 4e-07
15910 49 1e-06
06405 49 2e-06
00300 48 3e-06
11780 48 4e-06
16003 48 4e-06
01392 47 6e-06
13078 47 7e-06
13840 46 1e-05
17975 45 2e-05
22005 45 2e-05
13592 45 3e-05
09606 45 3e-05
19301 44 5e-05
05084 44 6e-05
32359 42 2e-04
26156 42 3e-04
12721 41 5e-04
16350 40 8e-04
02638 40 8e-04
20152 40 8e-04
00394 38 0.005
15549 37 0.010
31789 36 0.015
20773 35 0.037
03240 34 0.042
17644 34 0.054
14420 33 0.092
32357 33 0.12
38560 33 0.13
35032 32 0.20
15931 32 0.27
17253 32 0.28
21433 32 0.29
37602 31 0.56
20513 30 1.0
27546 30 1.2
28157 30 1.2
21210 28 2.7
17516 28 4.1
13305 28 4.5
17806 27 5.8
04852 27 6.2
26052 27 6.5
00392 27 8.5
>01060
Length = 1800
Score = 260 bits (664), Expect = 3e-70, Method: Compositional matrix adjust.
Identities = 138/295 (46%), Positives = 177/295 (60%), Gaps = 57/295 (19%)
Frame = +1
Query: 1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH 60
+ D T +KIGEGTYGVVYK RH+ TG+ +AMKKIRL E+GVPS+AIREI++L+ELRH
Sbjct: 70 LSDLTDFQKIGEGTYGVVYKCRHRATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELRH 249
Query: 61 PNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVK-----VVT------ 109
NIV L+DV+M+D RL+L+FEFLSMDLK Y+D P G +D LVK +VT
Sbjct: 250 TNIVCLEDVIMEDERLFLVFEFLSMDLKMYIDKFPEGVVLDRRLVKSYVFQIVTGIXFCH 429
Query: 110 ---LWYR--SPEVLL------------GSAR----------------------------- 123
+ +R P+ LL G AR
Sbjct: 430 QRRIVHRDLKPQNLLINHTGAIKIADFGMARTFALPVRAYTHEVVTLWYRAPEILMGASK 609
Query: 124 YSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNT 183
YSTPVD+WSIGTIFA++ + P+F GDSEIDQLF+IFR +GTP + WPE L +
Sbjct: 610 YSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKLPAFNGM 789
Query: 184 FPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLDNQIK 238
FP WK G L+ + +LD GLDL+ + L DPA+RIS K L H YF ++D +K
Sbjct: 790 FPLWKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYFLNVDTSVK 954
>14126
Length = 1265
Score = 178 bits (451), Expect = 2e-45, Method: Compositional matrix adjust.
Identities = 115/299 (38%), Positives = 153/299 (51%), Gaps = 65/299 (21%)
Frame = +3
Query: 2 EDYTKIEKIGEGTYGVVYKGRH-KTTGQVVAMKKIRLESEEEGVPSTAIREISLLKEL-- 58
+ Y ++ IG G YG VYK R + G+ VAMK+IRL + EEG+P AIREIS+LK+L
Sbjct: 189 QKYEEVAVIGNGAYGTVYKARDLRNQGEFVAMKRIRLNNTEEGMPMMAIREISMLKQLEQ 368
Query: 59 -RHPNIVSLQDVLM-----QDSRLYLIFEFLSMDLKKYLDSIP-PG-------------- 97
HPN+V L DV ++ RL L+FE++ DL YL P PG
Sbjct: 369 YEHPNVVRLLDVSHNTITDREIRLNLVFEYIEHDLATYLAKCPSPGLGPDRIKDLMLQLL 548
Query: 98 -----------------------------QYMDSSLVKV-----------VTLWYRSPEV 117
+ D L ++ VTLWYRSPEV
Sbjct: 549 NGVDFLHSNRIVHRDLKPQNLLISKDGRLKLADFGLARIYSFHMALTTVVVTLWYRSPEV 728
Query: 118 LLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESL 177
L+ A Y T VDIWS G IFAEL T++ LF G SE DQL +IF +G P WPE S+
Sbjct: 729 LM-QAEYGTSVDIWSCGCIFAELFTRRALFKGSSEFDQLKKIFEVIGLPPAGDWPEGVSV 905
Query: 178 QDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYF-NDLDN 235
++N+F P L + V +D DL+ KML++ +RIS + +L HPY +DLD+
Sbjct: 906 --HRNSFRPTPPVPLQTLVPEMDPQAKDLMEKMLVFKSGRRISSRESLLHPYLRDDLDS 1076
>32000
Length = 644
Score = 168 bits (426), Expect = 1e-42, Method: Compositional matrix adjust.
Identities = 77/128 (60%), Positives = 98/128 (76%)
Frame = -1
Query: 106 KVVTLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGT 165
+V+TLWYR+PE+LLG YS PVDIWS+G IF E+ T++ LF GDSEIDQL+RIFR LGT
Sbjct: 509 EVITLWYRAPEILLGCRFYSVPVDIWSLGCIFVEMMTRRALFPGDSEIDQLYRIFRTLGT 330
Query: 166 PNNEVWPEVESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMAL 225
P+ +VWP V L DYK TFPKW +L + V +L + GLDLL +ML Y+P +RIS + A+
Sbjct: 329 PDEKVWPGVSKLPDYKPTFPKWPLKNLET-VVSLSKVGLDLLKRMLTYNPNRRISARSAM 153
Query: 226 NHPYFNDL 233
HPYFND+
Sbjct: 152 RHPYFNDM 129
>24241
Length = 413
Score = 143 bits (361), Expect = 5e-35, Method: Compositional matrix adjust.
Identities = 66/105 (62%), Positives = 85/105 (80%), Gaps = 1/105 (0%)
Frame = -2
Query: 6 KIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPN-IV 64
++ KIGEGTYGVVYK RH+ TG+ +AMKKIRL E+GVPS+AIREI++L+ELRH +V
Sbjct: 331 RLSKIGEGTYGVVYKCRHRATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTQXLV 152
Query: 65 SLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKVVT 109
L+DV+M+D RL+L+FEFLSMDLK Y+D P G +D LVK+VT
Sbjct: 151 CLEDVIMEDERLFLVFEFLSMDLKMYIDKFPEGVVLDRRLVKIVT 17
>01966
Length = 1735
Score = 142 bits (358), Expect = 1e-34, Method: Compositional matrix adjust.
Identities = 62/119 (52%), Positives = 83/119 (69%)
Frame = -3
Query: 120 GSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQD 179
G+++YSTPVD+WSIGTIFA++ + P+F GDSEIDQLF+IFR +GTP + WPE L
Sbjct: 1187 GASKYSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKLPA 1008
Query: 180 YKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLDNQIK 238
+ FP WK G L+ + +LD GLDL+ + L DPA+RIS K L H YF ++D +K
Sbjct: 1007 FNGMFPLWKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYFLNVDTSVK 831
Score = 119 bits (298), Expect(2) = 1e-29, Method: Compositional matrix adjust.
Identities = 54/85 (63%), Positives = 69/85 (81%)
Frame = -1
Query: 22 RHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQDVLMQDSRLYLIFE 81
RH+ TG+ +AMKKIRL E+GVPS+AIREI++L+ELRH NIV L+DV+M+D RL+L+FE
Sbjct: 1651 RHRATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTNIVCLEDVIMEDERLFLVFE 1472
Query: 82 FLSMDLKKYLDSIPPGQYMDSSLVK 106
FLSMDLK Y+D P G +D LVK
Sbjct: 1471 FLSMDLKMYIDKFPEGVVLDRRLVK 1397
Score = 27.3 bits (59), Expect(2) = 1e-29, Method: Compositional matrix adjust.
Identities = 11/14 (78%), Positives = 13/14 (92%)
Frame = -2
Query: 6 KIEKIGEGTYGVVY 19
++ KIGEGTYGVVY
Sbjct: 1698 RLSKIGEGTYGVVY 1657
Score = 37.0 bits (84), Expect = 0.008, Method: Compositional matrix adjust.
Identities = 25/82 (30%), Positives = 37/82 (45%), Gaps = 3/82 (3%)
Frame = -1
Query: 106 KVVTLWYRSPEVLLGSARYSTPVDIWSIGTI--FAELATKKPL-FHGDSEIDQLFRIFRA 162
+VVTLWYR+PE+L+G STP W+ G + + + + PL ++ R +
Sbjct: 1228 EVVTLWYRAPEILMGPQ--STP-PXWTCGALEPSSPICSSGPLSSRATPKLTSFLRYSGS 1058
Query: 163 LGTPNNEVWPEVESLQDYKNTF 184
L N P S Q F
Sbjct: 1057 LALQRNRRGPSFTSCQHSMACF 992
>03294
Length = 1684
Score = 131 bits (330), Expect = 2e-31, Method: Compositional matrix adjust.
Identities = 58/112 (51%), Positives = 76/112 (67%)
Frame = -1
Query: 127 PVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNTFPK 186
PVD+WSIGTIFA++ + P+F GDSEIDQLF+IFR +GTP + WPE L + FP
Sbjct: 1675 PVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKLPAFNGMFPL 1496
Query: 187 WKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLDNQIK 238
WK G L+ + +LD GLDL+ + L DPA+RIS K L H YF ++D +K
Sbjct: 1495 WKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYFLNVDTSVK 1340
>01707
Length = 757
Score = 130 bits (328), Expect = 4e-31, Method: Compositional matrix adjust.
Identities = 80/220 (36%), Positives = 116/220 (52%), Gaps = 56/220 (25%)
Frame = +1
Query: 1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEG-VPSTAIREISLLKELR 59
ME Y KI KIGEG+YGVV+K R+K T Q+VA+KK +ESE++ + A+REI +LK+L+
Sbjct: 61 MEKYEKIGKIGEGSYGVVFKCRNKETSQLVAIKKF-VESEDDPLIKKIAMREIRMLKQLK 237
Query: 60 HPNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPG---------------------Q 98
HPN+V L +V + RL+L+F+++ L LD P G Q
Sbjct: 238 HPNLVRLIEVFRRKKRLHLVFDYVDHTLLNELDRYPRGLPEPMVKRIIYQTLLAVNFCHQ 417
Query: 99 Y----------------------MDSSLVKVVT------------LWYRSPEVLLGSARY 124
Y D +++T WYR+PE+L+G +Y
Sbjct: 418 YNTIHRDVKPENILITRQGQVKLCDFGFARILTGPGDEYTDYVATRWYRAPELLVGDTQY 597
Query: 125 STPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALG 164
PVD+W+IG +FAEL T + L+ G S++DQL I + LG
Sbjct: 598 GPPVDVWAIGCVFAELLTGQALWPGRSDVDQLHLIRKTLG 717
>01756
Length = 1858
Score = 122 bits (306), Expect = 1e-28, Method: Compositional matrix adjust.
Identities = 95/296 (32%), Positives = 137/296 (46%), Gaps = 69/296 (23%)
Frame = -3
Query: 4 YTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNI 63
Y K+ KIG+GT+G V+K R K T QVVAMKK+ +++E+EG P TA+REI +L+ L H N+
Sbjct: 1736 YEKLAKIGQGTFGEVFKARCKKTKQVVAMKKVLMDNEKEGFPITALREIKILQLLNHENV 1557
Query: 64 VSLQDVLMQ--------DSRLYLIFEFLSMDL----------------KKYLDSIPPGQY 99
V L ++ S YL+FEF DL K+ + + G Y
Sbjct: 1556 VDLIEICSTKATSANRYKSMFYLVFEFCEHDLAGLLSNMSVVFNLPEIKEVMKQLMNGLY 1377
Query: 100 ---------------------------MDSSLVKVVTLWYRSP---------------EV 117
D L + ++ R P E+
Sbjct: 1376 YIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRPPEL 1197
Query: 118 LLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESL 177
LLG YST +D W G I AE+ T+ P+ G +E +QL I + G+ EVWP VE L
Sbjct: 1196 LLGDRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQNQLTLITQLCGSITPEVWPGVERL 1017
Query: 178 QDYKN-TFPKWKPGSLASHVKNL--DENGLDLLSKMLIYDPAKRISGKMALNHPYF 230
+ Y + P+ + ++ D LDLL K+L DP KR++ AL+H +F
Sbjct: 1016 ELYNSLDLPQGNKRKVKERLRYYIKDAYALDLLDKLLALDPGKRVNSDEALSHDFF 849
>29581
Length = 1278
Score = 113 bits (282), Expect = 8e-26, Method: Compositional matrix adjust.
Identities = 76/246 (30%), Positives = 110/246 (44%), Gaps = 58/246 (23%)
Frame = -2
Query: 45 PSTAIREISLLKELRHPNIVSLQDVLMQDS--RLYLIFEFLSMDLKKYLDSIPPG----- 97
PS + L LRH NIV LQ+V++ S L+L+ E+ DL LD++P
Sbjct: 1223 PSVVCVRSTFLLNLRHQNIVQLQEVVVGKSLDSLFLVMEYCEQDLASLLDNMPAPFSESQ 1044
Query: 98 ------------QYM------------------DSSLVKV-------------------- 107
+Y+ D VK+
Sbjct: 1043 VKCIVLQLLKGLRYLHEAFIIHRDLKVSNLLMTDKGCVKIADFGLARNYGKPQKPMTPKV 864
Query: 108 VTLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPN 167
VTLWYR+PE+L GS +ST +D+WS G I EL KPL G S++ Q+ I LGTPN
Sbjct: 863 VTLWYRAPELLFGSKTHSTAIDMWSAGCILGELLGHKPLMPGRSDLQQIELIMELLGTPN 684
Query: 168 NEVWPEVESLQDYKNTFPKWKP-GSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALN 226
+ +WP L ++ K +P +L L E+G+ LL+ + +Y P KR + + L
Sbjct: 683 DTIWPGFSQLPAFEQFTLKKQPYNNLRHTFPWLSESGIRLLNGLFMYHPQKRATAEDCLE 504
Query: 227 HPYFND 232
H YF +
Sbjct: 503 HSYFKE 486
Score = 32.0 bits (71), Expect = 0.26, Method: Compositional matrix adjust.
Identities = 12/34 (35%), Positives = 23/34 (67%)
Frame = -1
Query: 28 QVVAMKKIRLESEEEGVPSTAIREISLLKELRHP 61
++VA+KK+R+ E G+P + +REI++ + P
Sbjct: 1275 EIVALKKMRMTGERYGIPISGLREINIFAQSATP 1174
>04138
Length = 800
Score = 105 bits (263), Expect = 1e-23, Method: Compositional matrix adjust.
Identities = 67/191 (35%), Positives = 101/191 (52%), Gaps = 10/191 (5%)
Frame = +1
Query: 50 REISLLKELRHPNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKVVT 109
R L ++++ NI+ + +++ + L F S++L++ P +Y + +VVT
Sbjct: 67 RNKILHRDMKAANILITKQGVLKLADFGLARAF-SVNLRQ------PNRYTN----RVVT 213
Query: 110 LWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNE 169
LWYR PE+LLG YST +D W G I AE+ T+ P+ G +E +QL I + G+ E
Sbjct: 214 LWYRPPELLLGDRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQNQLTLITQLCGSITPE 393
Query: 170 VWPEVESLQDYKNTFPKWKPGSLASHVKNL----------DENGLDLLSKMLIYDPAKRI 219
VWP V L Y G+LA+ KN+ D GLDL ++L DP++RI
Sbjct: 394 VWPGVTQLSMYHQI-----KGALAAGRKNIIRDRFARILKDPYGLDLFERLLKMDPSQRI 558
Query: 220 SGKMALNHPYF 230
S ALNH +F
Sbjct: 559 SADEALNHDFF 591
>20559
Length = 430
Score = 103 bits (256), Expect(2) = 2e-23, Method: Compositional matrix adjust.
Identities = 45/80 (56%), Positives = 65/80 (81%)
Frame = -2
Query: 1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH 60
M+ Y K+EKIGEGTYG V+K +++ T ++VA+K++RL+ ++EGVPS+A+REI LLKEL+H
Sbjct: 378 MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKH 199
Query: 61 PNIVSLQDVLMQDSRLYLIF 80
NIV L DVL + +L L+F
Sbjct: 198 RNIVRLHDVLHSERKLTLVF 139
Score = 23.1 bits (48), Expect(2) = 2e-23, Method: Compositional matrix adjust.
Identities = 8/15 (53%), Positives = 10/15 (66%)
Frame = -3
Query: 80 FEFLSMDLKKYLDSI 94
FE+ DLKKY D+
Sbjct: 140 FEYCDQDLKKYFDTC 96
>04591
Length = 1117
Score = 97.4 bits (241), Expect = 5e-21, Method: Compositional matrix adjust.
Identities = 53/128 (41%), Positives = 75/128 (58%), Gaps = 3/128 (2%)
Frame = -2
Query: 106 KVVTLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGT 165
+VVTLWYR PE+LLG Y +D+W +G I AE+ ++KPL G SE QL I G+
Sbjct: 720 RVVTLWYRPPELLLGEREYGPEIDMWGVGCIMAEMWSRKPLMQGRSEQHQLSLITDLCGS 541
Query: 166 PNNEVWPEVESLQDY-KNTFPKWKPGSLASHVKNLDEN--GLDLLSKMLIYDPAKRISGK 222
N EVWP V L+ Y K P+ KP + + +L +N G +L+ L DP +R++
Sbjct: 540 LNAEVWPGVTKLELYGKLDLPQGKPRKVKERMLDLLKNKEGAELIDIFLRLDPGQRMNCD 361
Query: 223 MALNHPYF 230
AL+H +F
Sbjct: 360 NALSHDFF 337
Score = 47.4 bits (111), Expect = 5e-06, Method: Compositional matrix adjust.
Identities = 24/62 (38%), Positives = 36/62 (58%), Gaps = 8/62 (12%)
Frame = -2
Query: 41 EEGVPSTAIREISLLKELRHPNIVSLQDVLMQD--------SRLYLIFEFLSMDLKKYLD 92
+EG P TA+REI +L++L H N+V LQ++ S YLIFE+ DL L+
Sbjct: 1101 KEGFPITALREIKILQQLEHENVVQLQEICHTQAGPYNRYKSTFYLIFEYCDYDLAGLLN 922
Query: 93 SI 94
++
Sbjct: 921 NL 916
>23319
Length = 2235
Score = 96.3 bits (238), Expect = 1e-20, Method: Compositional matrix adjust.
Identities = 51/118 (43%), Positives = 71/118 (60%), Gaps = 2/118 (1%)
Frame = +3
Query: 124 YSTPVDIWSIGTIFAELATK-KPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKN 182
YST +D+WS G IFAELA +PLF G+ + DQL RIF+ LGTP + WP + L +Y+
Sbjct: 27 YSTSIDMWSAGCIFAELANAGRPLFPGNDDDDQLKRIFKLLGTPTEDQWPGMTQLPNYR- 203
Query: 183 TFPKWKPGSLASH-VKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLDNQIKK 239
FP + + V L+ G DLL +L+ P+ R+S AL HPYF DL +++
Sbjct: 204 MFPMYHVTTTWQQVVPKLNSKGRDLLQCLLVCCPSDRMSADEALQHPYFADLPPLVRQ 377
>12453
Length = 680
Score = 75.9 bits (185), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 38/102 (37%), Positives = 57/102 (55%), Gaps = 1/102 (0%)
Frame = +3
Query: 133 IGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKN-TFPKWKPGS 191
+G IF E+A +PLF G + D+L IF+ LGTP + P + D+ P ++ +
Sbjct: 6 VGCIFYEMACGRPLFPGSTVEDELHLIFKTLGTPTEDSLPSISRNPDFLALNLPHYQGEA 185
Query: 192 LASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDL 233
L + LD +GLDLL+K L Y+ R+S +L H +FN L
Sbjct: 186 LITIAPRLDSDGLDLLAKFLKYNAKIRVSAADSLKHSFFNSL 311
>18287
Length = 678
Score = 66.2 bits (160), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 37/112 (33%), Positives = 60/112 (53%), Gaps = 3/112 (2%)
Frame = -3
Query: 124 YSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNE-VWPEVESLQDY-- 180
Y +DIWS+G IFAEL +++ LF + QL I +GTP E + E +++
Sbjct: 673 YDYSIDIWSVGCIFAELLSRRILFQAQGPVQQLDMIINLVGTPRPEDMERACEGARNHIL 494
Query: 181 KNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFND 232
F + +L + + + LL++MLI +P RIS + AL+HPY ++
Sbjct: 493 NQPFRRQNLLTLYNLSPHATHEAVRLLTRMLILNPKNRISAEEALSHPYLDE 338
>26909
Length = 394
Score = 61.6 bits (148), Expect = 3e-10, Method: Compositional matrix adjust.
Identities = 36/113 (31%), Positives = 52/113 (46%), Gaps = 18/113 (15%)
Frame = +2
Query: 136 IFAELATKKPLFHGDSE---------IDQLFRIFRALGTPNNEVWPEVESLQDYKNTFPK 186
IFAEL T +P+FH E DQL RIF +G P + W ++ + +++
Sbjct: 2 IFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFPQEKDWEDIRRMPEHQQLTKD 181
Query: 187 WKPGS---------LASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYF 230
+K S + H D LL K+L DP KRI+ + A+ PYF
Sbjct: 182 FKRSSYVNCNLMKYMEKHKVKADSKAFHLLQKLLTMDPVKRITSEQAMKDPYF 340
>28638
Length = 1458
Score = 40.4 bits (93), Expect(2) = 1e-09, Method: Compositional matrix adjust.
Identities = 18/35 (51%), Positives = 24/35 (68%)
Frame = -1
Query: 111 WYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKP 145
+YRSPEVLLG Y +D+WS+G I E+ T +P
Sbjct: 639 FYRSPEVLLG-VPYDLAIDMWSLGCILVEMHTGEP 538
Score = 38.9 bits (89), Expect(2) = 1e-09, Method: Compositional matrix adjust.
Identities = 33/126 (26%), Positives = 50/126 (39%), Gaps = 34/126 (26%)
Frame = -2
Query: 145 PLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNTFP-------------KWK-PG 190
PLF G +E DQ+ +I LG P + + + + Y + P K+K P
Sbjct: 539 PLFAGSNEFDQMMKIVEVLGVPPRHILDQAQKTRKYFDLLPDGTYAPKKPRDNKKYKSPS 360
Query: 191 SLASH-----------VKNLDENG---------LDLLSKMLIYDPAKRISGKMALNHPYF 230
S H + + E G DL+ +ML +DP RIS AL H +F
Sbjct: 359 SRKLHEVLGAEKGGPGGRRMGEPGHTVADYLKFKDLILRMLDFDPKTRISPYYALQHNFF 180
Query: 231 NDLDNQ 236
++
Sbjct: 179 RKTSDE 162
>18401
Length = 463
Score = 57.4 bits (137), Expect = 5e-09, Method: Compositional matrix adjust.
Identities = 50/147 (34%), Positives = 68/147 (46%), Gaps = 22/147 (14%)
Frame = -3
Query: 107 VVTLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALG-- 164
V T YR+PEV+L +S P D+WS+G I EL T LF + L + R LG
Sbjct: 449 VSTRHYRAPEVILELG-WSHPCDVWSVGCIMFELYTGYTLFQTHDNKEHLAMMERILGSL 273
Query: 165 -------TPNNEVW-------PEVESLQDY--KNTFPKWKPGSLASHVK---NLDENGL- 204
T + + PE S+ Y +NT P L +VK N D L
Sbjct: 272 PYRMAKKTKKQKYFHHGRLDVPERSSMARYVRENTKP------LLRYVKDRENKDHQQLF 111
Query: 205 DLLSKMLIYDPAKRISGKMALNHPYFN 231
DL+ K+L Y+ + R S AL HP+F+
Sbjct: 110 DLMKKLLAYEASSRYSLLQALQHPFFS 30
>01718
Length = 959
Score = 53.5 bits (127), Expect = 7e-08, Method: Compositional matrix adjust.
Identities = 30/93 (32%), Positives = 55/93 (59%), Gaps = 1/93 (1%)
Frame = +3
Query: 1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH 60
++D+ EKIG G + V+K H+ TGQV+A+K + S + +RE+ LL L+H
Sbjct: 147 LDDFI-CEKIGAGFFSEVFKVTHRITGQVMALKMNTMTSNRHNM----LREVQLLNRLQH 311
Query: 61 PNIVSLQDVLMQDSRLYLIFEFL-SMDLKKYLD 92
NI+ V + + +L+ + E++ S +L++ L+
Sbjct: 312 ANILRFMGVCVHEGQLHALTEYIPSGNLEQLLE 410
>03508
Length = 1463
Score = 52.8 bits (125), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 35/114 (30%), Positives = 55/114 (48%), Gaps = 14/114 (12%)
Frame = +2
Query: 131 WSIGTIFAEL----ATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQ-DYKNTF- 184
W+ G A L + K P FHG DQL RI + LGT ++++ +E Q D F
Sbjct: 1118 WTCGVWAACLPA*SSGKSPFFHGHDNYDQLVRIAKVLGT--DDLYGYIEKYQIDLDPRFN 1291
Query: 185 --------PKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYF 230
+W+ + + + LD L K+L YD +R++ + A++HPYF
Sbjct: 1292 DILGRHSRKRWERFVHSENQHLISPEALDFLDKLLRYDHNERLTAREAMDHPYF 1453
Score = 38.5 bits (88), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 14/40 (35%), Positives = 26/40 (65%)
Frame = +1
Query: 105 VKVVTLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKK 144
V+V + +++ PE+LL Y +D+WS+G +FA + +K
Sbjct: 1048 VRVASRYFKGPELLLDYQMYDYSLDMWSLGCMFASMIFRK 1167
>18921
Length = 697
Score = 51.2 bits (121), Expect = 4e-07, Method: Compositional matrix adjust.
Identities = 24/76 (31%), Positives = 49/76 (64%)
Frame = +2
Query: 9 KIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQD 68
K+GEG+YG V+K HK TGQV+A+K++ ++++ + + I+EIS++++ IV
Sbjct: 50 KLGEGSYGSVFKSLHKETGQVLAIKQVPVDTDLQEI----IKEISIMQQCDSKYIVKYYG 217
Query: 69 VLMQDSRLYLIFEFLS 84
+++ L+++ E+
Sbjct: 218 SYFKNTDLWIVMEYCG 265
>15910
Length = 1361
Score = 49.3 bits (116), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 33/129 (25%), Positives = 54/129 (41%)
Frame = +2
Query: 112 YRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVW 171
Y +PEVL G +Y+ VD+WS+G I L F ++E + +I + + E W
Sbjct: 668 YCAPEVLKGD-KYTPSVDMWSVGVIAYILLCGYEPFFAENEFEMYRKIIKGEYKFDEEYW 844
Query: 172 PEVESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFN 231
E+ EN D++ K+L+ DP KR++ AL P+
Sbjct: 845 SEI-------------------------SENAKDVVRKLLVIDPKKRLTATEALRLPWVK 949
Query: 232 DLDNQIKKM 240
+ + M
Sbjct: 950 GVATKTTNM 976
>06405
Length = 1965
Score = 48.5 bits (114), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 27/86 (31%), Positives = 50/86 (58%), Gaps = 1/86 (1%)
Frame = +1
Query: 9 KIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQD 68
++G G YG VY+ K ++VA+K ++ E+ + + E +++KE++HPN+V L
Sbjct: 280 RLGGGQYGDVYEAMWKRYNKIVAVKTLK---EDTMALNDFLEEAAIMKEMKHPNLVQLLG 450
Query: 69 VLMQDSRLYLIFEFLSM-DLKKYLDS 93
V ++ Y++ EF+ +L YL S
Sbjct: 451 VCTREPPFYIVTEFMPHGNLLDYLRS 528
>00300
Length = 2318
Score = 48.1 bits (113), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 54/279 (19%), Positives = 100/279 (35%), Gaps = 58/279 (20%)
Frame = -1
Query: 9 KIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQD 68
KIGEG +G VY + +TG+++A+K+++ + + EI + + ++H N+V
Sbjct: 1637 KIGEGQFGKVYTAVNMSTGELMALKEMKFQPNDLQQLREMCDEIKIFEGIQHENLVKYYG 1458
Query: 69 VLMQDSRLYLIFEFL---------SMDLKKYL---------------------------- 91
V + + + E+ M L +YL
Sbjct: 1457 VEVHKDEMLMFMEYCDTGTIEEAAKMGLPEYLIRRYTREIVLAVNHLHENSIVHRDIKGA 1278
Query: 92 -------DSIPPGQYMDSSLVKVVTLWYRSPEVLLGSARYSTP--------------VDI 130
+ G + S +K T L+G+ Y P DI
Sbjct: 1277 NIFLTSNGHVKLGDFGCSVKLKSHTTMPGEFHNLVGTTAYMAPEVFTQNDQGGYGRAADI 1098
Query: 131 WSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNTFPKWKPG 190
WS+G + E+AT K +H ++D ++I +G + P+ S++
Sbjct: 1097 WSLGCVVIEMATGKRPWH---DLDNNYQIMYKVGIGHKPAVPDSLSVE------------ 963
Query: 191 SLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPY 229
G L ++ +DPA+R L+H +
Sbjct: 962 ------------GKHFLDLIMCHDPAQRALASQLLDHTF 882
>11780
Length = 1713
Score = 47.8 bits (112), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 31/87 (35%), Positives = 56/87 (64%), Gaps = 1/87 (1%)
Frame = +3
Query: 8 EKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQ 67
E IG+G +G VYKG ++ GQ VA+K+++ + E + ++E S++ LRH N+V L
Sbjct: 615 EAIGKGDFGDVYKGMYR--GQPVAIKQLKDKDRGE---QSFLQEASVMTSLRHDNLVRLI 779
Query: 68 DVLMQDSRLYLIFEFLSM-DLKKYLDS 93
V++ ++ ++L+ EF+ +L +YL S
Sbjct: 780 GVVLGET-IFLVTEFMGKGNLVEYLRS 857
>16003
Length = 926
Score = 47.8 bits (112), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 33/88 (37%), Positives = 46/88 (52%)
Frame = -1
Query: 145 PLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNTFPKWKPGSLASHVKNLDENGL 204
P GD+++DQL +IF LGTP WP V SL DY F + L ++ L
Sbjct: 911 PFLPGDTDLDQLGKIFNMLGTPTETEWPAVTSLPDYIQ-FKHCQKQPLKEIFTAAGDDLL 735
Query: 205 DLLSKMLIYDPAKRISGKMALNHPYFND 232
+LL K+L +P R + AL PYF++
Sbjct: 734 ELLDKLLAMNPLHRCTATQALKMPYFSN 651
>01392
Length = 1806
Score = 47.4 bits (111), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 42/165 (25%), Positives = 69/165 (41%), Gaps = 21/165 (12%)
Frame = -1
Query: 87 LKKYLDSIPPGQYMDSSLVKVVTL---WYRSPEVL--LGSARYSTP-------------- 127
L ++LD + P + D L ++ ++PE+L +GSA Y P
Sbjct: 1695 LCEHLDDVVPVKICDFDLASGISCDGDGTKTPELLTPVGSAEYMAPEVVDAWVGDSFSYD 1516
Query: 128 --VDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNTFP 185
D+WS+G I + P F+G D + A + ++ S+QD FP
Sbjct: 1515 KRCDLWSLGIILYIMLCGYPPFYGQCGEDCGWNRGEACHDCQDMLF---NSIQDGHYKFP 1345
Query: 186 KWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYF 230
+ S++S K DL+ +L+ +P KR S L HP+
Sbjct: 1344 SQEWTSISSSAK-------DLIRHLLVREPRKRYSAADVLKHPWI 1231
>13078
Length = 773
Score = 47.0 bits (110), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 36/126 (28%), Positives = 56/126 (44%), Gaps = 16/126 (12%)
Frame = -1
Query: 124 YSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNT 183
+S P D+WSIG I EL T LF + L + R LG+ + + + + + +
Sbjct: 746 WSQPCDVWSIGCIMFELYTGYTLFQTHDNKEHLAMMERILGSLPYRMAKKTKKQKYFYHG 567
Query: 184 FPKWKPGSLAS------------HVKNLD----ENGLDLLSKMLIYDPAKRISGKMALNH 227
W S A +VK+ D + DL+ KML Y+ + R S + A+ H
Sbjct: 566 RLDWDEKSSAGRYVRDNVKPLRRYVKDPDNEDHQQLFDLMDKMLSYEVSTRYSLRQAMRH 387
Query: 228 PYFNDL 233
P+F L
Sbjct: 386 PFFRKL 369
>13840
Length = 446
Score = 46.2 bits (108), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 27/89 (30%), Positives = 42/89 (47%)
Frame = -1
Query: 2 EDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHP 61
ED + +IG G YG V K RHK T V+A+K+IR EE + +++ P
Sbjct: 395 EDMQDMGEIGRGNYGTVNKMRHKITSTVMAVKRIRSTVEEREQKQLLMDLDVVMRSNNCP 216
Query: 62 NIVSLQDVLMQDSRLYLIFEFLSMDLKKY 90
IV L ++ ++ E + L K+
Sbjct: 215 FIVQFYGALFKEGDCWICMELMETSLDKF 129
>17975
Length = 449
Score = 45.4 bits (106), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 25/68 (36%), Positives = 39/68 (57%)
Frame = +3
Query: 15 YGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQDVLMQDS 74
+ VV RH TG+ VA+K I +E S +E+ +K ++HPN+V L +V+ +
Sbjct: 6 FAVVKLARHVFTGEKVAVKVIDKTKLDEVSRSHLFQEVRCMKLVQHPNVVRLYEVIDTQT 185
Query: 75 RLYLIFEF 82
+LYLI E
Sbjct: 186KLYLILEL 209
>22005
Length = 873
Score = 45.4 bits (106), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 34/101 (33%), Positives = 47/101 (46%), Gaps = 11/101 (10%)
Frame = +1
Query: 10 IGEGTYGVVYK----GRHKTTGQVVAMK------KIRLESEEEGVPSTAIREISLLKELR 59
IG+G +G V K G G+++ K K+ E E + S RE SL+ +
Sbjct: 7 IGQGAFGRVSKLKFLGLASLVGELIPEKRP*LL*KMLKEDASEDLQSDFEREASLMADFD 186
Query: 60 HPNIVSLQDVLMQDSRLYLIFEFLSM-DLKKYLDSIPPGQY 99
HPNIV L V + L+FEF+S DL +L P Y
Sbjct: 187 HPNIVKLLGVCAIGKPMCLLFEFMSKGDLNDFLRLCSPENY 309
>13592
Length = 980
Score = 45.1 bits (105), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 22/76 (28%), Positives = 40/76 (52%)
Frame = +2
Query: 9 KIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQD 68
KIG+G +G VY + TG+++AMK+I ++ E E+ +L+ ++H N+V
Sbjct: 5 KIGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETRALKNVAEELKILEGIKHKNLVRYYG 184
Query: 69 VLMQDSRLYLIFEFLS 84
+ + L + E S
Sbjct: 185IEVHREELLIFMELCS 232
Score = 36.6 bits (83), Expect = 0.009, Method: Compositional matrix adjust.
Identities = 30/117 (25%), Positives = 47/117 (40%), Gaps = 3/117 (2%)
Frame = +2
Query: 107 VVTLWYRSPEVLL--GSARYSTPVDIWSIGTIFAELAT-KKPLFHGDSEIDQLFRIFRAL 163
V T Y +PEV S + DIWS+G + E+A+ K+P ++ D F+I +
Sbjct: 476 VGTQAYMAPEVFTKTNSDGHGRLADIWSVGCVVVEMASGKRPW----AQFDSNFQIMFKV 643
Query: 164 GTPNNEVWPEVESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRIS 220
G PE +L + G D + L +DP +R+S
Sbjct: 644 GMGEKPQAPE------------------------SLSQEGHDFIDHCLQHDPKQRLS 742
>09606
Length = 1300
Score = 44.7 bits (104), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 22/84 (26%), Positives = 42/84 (50%)
Frame = -3
Query: 1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH 60
ME++ E++G+G + ++YKGR K T VA+ I E+ + + ++ H
Sbjct: 1118 MENFVLYEELGKGEHSIIYKGRRKGTINFVAIHCI-----EKCKRPEVTNTVRMTHDISH 954
Query: 61 PNIVSLQDVLMQDSRLYLIFEFLS 84
PN+V + + L+L+ E +
Sbjct: 953 PNVVQFHEWYETSNHLWLVVELCT 882
>19301
Length = 712
Score = 44.3 bits (103), Expect = 5e-05, Method: Compositional matrix adjust.
Identities = 33/107 (30%), Positives = 50/107 (46%), Gaps = 4/107 (3%)
Frame = +2
Query: 1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH 60
E T +E +G G G V+ G K + VA+KK+R + T IR L++L H
Sbjct: 302 FESITDLEWLGSGAQGAVFLG--KLCAEEVAVKKVR------DIKETDIRN---LRKLNH 448
Query: 61 PNIVSLQDVLMQDSRLYLIFEFLS----MDLKKYLDSIPPGQYMDSS 103
PNI+S + V Q +I E+ ++ + IPP +D S
Sbjct: 449 PNIISFKGVCTQAPCYCIIMEYCPYGQLYEVLRDGKEIPPALVLDWS 589
>05084
Length = 1324
Score = 43.9 bits (102), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 30/95 (31%), Positives = 50/95 (52%), Gaps = 3/95 (3%)
Frame = +2
Query: 149 GDSEIDQLFRIFRALGTPNNEVWPEVE-SLQDYKNTFPKWK--PGSLASHVKNLDENGLD 205
GDS +DQL I + LGTP E E+ + ++K FP+ K P + + E +
Sbjct: 8 GDSGVDQLVEIIKVLGTPTREQIREMNPNYSEFK--FPQIKAHPWTKVFRPRTPPE-AIQ 178
Query: 206 LLSKMLIYDPAKRISGKMALNHPYFNDLDNQIKKM 240
L+S++L Y P+ RI A H +F++L + ++
Sbjct: 179 LVSRLLEYTPSARIQPMEACAHAFFDELRDPASRL 283
>32359
Length = 928
Score = 42.4 bits (98), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 22/64 (34%), Positives = 39/64 (60%)
Frame = -1
Query: 4 YTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNI 63
YT + IG G++GVVY+ + T ++VA+KK+ + + RE+ ++++L H NI
Sbjct: 424 YTDAKVIGNGSFGVVYQAKLVDTSELVAIKKVLQDKRFKN------RELQIMRKLEHQNI 263
Query: 64 VSLQ 67
V L+
Sbjct: 262 VKLK 251
>26156
Length = 479
Score = 41.6 bits (96), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 23/86 (26%), Positives = 43/86 (50%), Gaps = 2/86 (2%)
Frame = -1
Query: 1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLE--SEEEGVPSTAIREISLLKEL 58
+ D+ + IG G+Y V + HK T ++ AMK I+ E +++E + +
Sbjct: 392 LTDFLLLRVIGRGSYAKVLQVEHKRTKRIYAMKVIKKELVNDDEDIDWVQTEKHVFETAT 213
Query: 59 RHPNIVSLQDVLMQDSRLYLIFEFLS 84
+P +V L +SRL+ + EF++
Sbjct: 212 NYPFLVGLHSCFQSESRLFFVIEFVN 135
>12721
Length = 821
Score = 40.8 bits (94), Expect = 5e-04, Method: Compositional matrix adjust.
Identities = 21/75 (28%), Positives = 43/75 (57%)
Frame = +1
Query: 9 KIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQD 68
KIGEG+ G+V + G+ +A+KK+ L ++ E+ ++++ HPNIV + +
Sbjct: 109 KIGEGSTGIVCIATSRD-GRQMAVKKMDLRKQQRR--ELLFNEVVVMRDYHHPNIVEMYN 279
Query: 69 VLMQDSRLYLIFEFL 83
+ + L+++ EF+
Sbjct: 280 SYLVNDELWVVMEFM 324
Score = 32.3 bits (72), Expect = 0.17, Method: Compositional matrix adjust.
Identities = 17/53 (32%), Positives = 28/53 (52%)
Frame = +1
Query: 107 VVTLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRI 159
V T ++ +PEV+ Y VDIWS+G + E+ +P F + + + RI
Sbjct: 556 VGTPYWMAPEVI-SRLPYGPEVDIWSLGIMVMEMIDAEPPFFNEPPLQAMRRI 711
>16350
Length = 1108
Score = 40.0 bits (92), Expect = 8e-04, Method: Compositional matrix adjust.
Identities = 21/41 (51%), Positives = 24/41 (58%)
Frame = +2
Query: 107 VVTLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLF 147
+ T YR EVL+G A Y TP DIWS + ELAT LF
Sbjct: 413 IQTRQYRCLEVLIG-AGYGTPADIWSTACMAFELATGDYLF 532
Score = 30.0 bits (66), Expect = 0.98, Method: Compositional matrix adjust.
Identities = 10/27 (37%), Positives = 16/27 (59%)
Frame = +3
Query: 205 DLLSKMLIYDPAKRISGKMALNHPYFN 231
D L+ ML +DP +R + +L HP+
Sbjct: 762 DFLAPMLEFDPEQRATAAQSLQHPWLK 842
>02638
Length = 1490
Score = 40.0 bits (92), Expect = 8e-04, Method: Compositional matrix adjust.
Identities = 31/123 (25%), Positives = 49/123 (39%)
Frame = +1
Query: 109 TLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNN 168
T+ + +PEVL G + Y D+WS+G + E+ T +P ++ + L IF+ + +
Sbjct: 25 TIAFMAPEVLRGES-YGRACDVWSVGCVMIEMCTCRPPWNSHDISNHLALIFKIASSVDP 201
Query: 169 EVWPEVESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHP 228
PE N+ DL+ + L D R S K L HP
Sbjct: 202 PPIPE------------------------NMSPPVRDLMLRCLEQDSDFRPSAKDLLMHP 309
Query: 229 YFN 231
F
Sbjct: 310 LFT 318
>20152
Length = 445
Score = 40.0 bits (92), Expect = 8e-04, Method: Compositional matrix adjust.
Identities = 31/120 (25%), Positives = 46/120 (38%)
Frame = +1
Query: 115 PEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEV 174
PE+LLG + + VD+WS+G I L + F ++ + L I
Sbjct: 1 PEILLGDSYDAPAVDVWSLGVILYMLVVGEAPFQEANDSETLTMIM-------------- 138
Query: 175 ESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLD 234
D + P ++ DL+ KML +P R S L HP+ ND D
Sbjct: 139 ----DCRYQIP-----------PHISHKCQDLIEKMLQREPVDRASLPHILAHPWLNDGD 273
>00394
Length = 548
Score = 37.7 bits (86), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 21/60 (35%), Positives = 31/60 (51%)
Frame = -2
Query: 9 KIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQD 68
+IG G++ VYKG G VA +++ + + E +LKEL+HPNIV D
Sbjct: 277 EIGRGSFKTVYKGLDTELGVAVAWCELQDKKWNKAERQRFKEEAEMLKELQHPNIVRFFD 98
>15549
Length = 470
Score = 36.6 bits (83), Expect = 0.010, Method: Compositional matrix adjust.
Identities = 14/39 (35%), Positives = 28/39 (71%)
Frame = -1
Query: 2 EDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESE 40
+++ IE++G+G YG+V++ ++K Q A+K+I L S+
Sbjct: 218 DEFECIEQMGKGGYGIVFRAKNKVDEQEYAVKRIALPSD 102
>31789
Length = 676
Score = 35.8 bits (81), Expect = 0.015, Method: Compositional matrix adjust.
Identities = 21/60 (35%), Positives = 31/60 (51%)
Frame = +2
Query: 9 KIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQD 68
+IG G++ VYKG G VA +++ + + E +LKEL+HPNIV D
Sbjct: 341 EIGRGSFKTVYKGLDTELGVAVAWCELQDKKWNKTERQRFKEEAEMLKELQHPNIVRFFD 520
>20773
Length = 391
Score = 34.7 bits (78), Expect = 0.037, Method: Compositional matrix adjust.
Identities = 11/35 (31%), Positives = 25/35 (71%)
Frame = -1
Query: 195 HVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPY 229
H + ++ +L+ ++L YDP++R++ +AL+HP+
Sbjct: 334 HTTVVTQHFYNLVQRLLTYDPSQRLTPDLALSHPF 230
>03240
Length = 1683
Score = 34.3 bits (77), Expect = 0.042, Method: Compositional matrix adjust.
Identities = 14/48 (29%), Positives = 26/48 (54%)
Frame = -3
Query: 112 YRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRI 159
Y +PEVL Y++ D WS+G I E+ P F+ ++ + +++
Sbjct: 661 YIAPEVLSRLGGYTSVCDWWSVGVILFEMLVGHPPFYANTPAETQYKV 518
>17644
Length = 463
Score = 33.9 bits (76), Expect = 0.054, Method: Compositional matrix adjust.
Identities = 11/35 (31%), Positives = 24/35 (68%)
Frame = +3
Query: 195 HVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPY 229
H + ++ BL+ ++L YDP++R++ +AL+HP+
Sbjct: 57 HTTVVTQHFYBLVQRLLTYDPSQRLTPDLALSHPF 161
>14420
Length = 528
Score = 33.1 bits (74), Expect = 0.092, Method: Compositional matrix adjust.
Identities = 29/116 (25%), Positives = 54/116 (46%)
Frame = +2
Query: 41 EEGVPSTAIREISLLKELRHPNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYM 100
+EG + RE E H N V +D+ D+ L + + + + + P Q
Sbjct: 191 DEGQIAAVCRECLQALEFLHENQVIHRDI-KSDNILLGMDGSVKLTDFGFCAQLSPEQSK 367
Query: 101 DSSLVKVVTLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQL 156
S++V T ++ +PEV+ +Y VDIWS+G + E+ +P + ++ + L
Sbjct: 368 RSTMVG--TPYWMAPEVVT-RKQYGPTVDIWSLGVMCIEMIEGEPPYLNENPLRAL 526
Score = 30.0 bits (66), Expect = 0.89, Method: Compositional matrix adjust.
Identities = 13/36 (36%), Positives = 24/36 (66%)
Frame = +2
Query: 49 IREISLLKELRHPNIVSLQDVLMQDSRLYLIFEFLS 84
I EI +++E ++PNIV+ D + L+++ EFL+
Sbjct: 44 INEILVMRENQNPNIVNYLDSYLVGEELWVVMEFLA 151
>32357
Length = 625
Score = 32.7 bits (73), Expect = 0.12, Method: Compositional matrix adjust.
Identities = 14/30 (46%), Positives = 22/30 (73%)
Frame = -2
Query: 4 YTKIEKIGEGTYGVVYKGRHKTTGQVVAMK 33
Y ++KIG G++G +Y G H T+G+ VA+K
Sbjct: 432 YRLMKKIGSGSFGEIYLGVHNTSGEEVAVK 343
>38560
Length = 479
Score = 32.7 bits (73), Expect = 0.13, Method: Compositional matrix adjust.
Identities = 31/121 (25%), Positives = 48/121 (39%), Gaps = 1/121 (0%)
Frame = -3
Query: 112 YRSPEVLLGSARYSTPVDIWSIGT-IFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEV 170
Y +PE++ G + DIWS+G ++A L P D + L
Sbjct: 387 YAAPELISGLEYLGSEADIWSMGVLLYALLCGYLPF--DDEKXSHL-------------- 256
Query: 171 WPEVESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYF 230
+ Q K+ P+W L E+ LL ML DP+ RI+ + L+H +
Sbjct: 255 ---*QKNQKRKDEVPEW-----------LSEDTTKLLEGMLQTDPSHRITIRRLLDHHWL 118
Query: 231 N 231
N
Sbjct: 117 N 115
>35032
Length = 465
Score = 32.0 bits (71), Expect = 0.20, Method: Compositional matrix adjust.
Identities = 12/27 (44%), Positives = 19/27 (70%)
Frame = +3
Query: 204 LDLLSKMLIYDPAKRISGKMALNHPYF 230
DL+ ++L YDP+KR++ AL HP+
Sbjct: 144 FDLVKRLLNYDPSKRLTPXXALAHPFL 224
>15931
Length = 447
Score = 31.6 bits (70), Expect = 0.27, Method: Compositional matrix adjust.
Identities = 13/30 (43%), Positives = 19/30 (63%)
Frame = +1
Query: 204 LDLLSKMLIYDPAKRISGKMALNHPYFNDL 233
DL+ KML Y+ + R S + A+ HP+F L
Sbjct: 76 FDLMDKMLSYEVSTRYSLRQAMRHPFFRKL 165
>17253
Length = 483
Score = 31.6 bits (70), Expect = 0.28, Method: Compositional matrix adjust.
Identities = 18/63 (28%), Positives = 31/63 (49%), Gaps = 2/63 (3%)
Frame = -1
Query: 38 ESEEEGVPSTAIREISLLKEL-RHPNIVSLQDVLMQDSRLYLIFEFLSM-DLKKYLDSIP 95
E+ + S +RE+S++++L RHPN+VS ++ EF DL +L
Sbjct: 438 EAATDAEKSEFLRELSIMRKLPRHPNVVSFMGCCTMSDPALILMEFCCHGDLLSFLRKRR 259
Query: 96 PGQ 98
P +
Sbjct: 258 PDR 250
>21433
Length = 590
Score = 31.6 bits (70), Expect = 0.29, Method: Compositional matrix adjust.
Identities = 26/86 (30%), Positives = 36/86 (41%)
Frame = +3
Query: 50 REISLLKELRHPNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKVVT 109
REI + LRH NI+ + +R+YLI EF P G+ L K +
Sbjct: 15 REIEIQSHLRHDNILRMFGYFHDKTRVYLILEF-----------APKGE-----LYKELQ 146
Query: 110 LWYRSPEVLLGSARYSTPVDIWSIGT 135
++ E + S PV WSI T
Sbjct: 147 RCHKFDENEQHAIYTSCPVP-WSIAT 221
>37602
Length = 804
Score = 30.8 bits (68), Expect = 0.56, Method: Compositional matrix adjust.
Identities = 12/30 (40%), Positives = 19/30 (63%)
Frame = -2
Query: 1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVV 30
++D+ I+++G GTYG VYK + T G
Sbjct: 512 LDDFELIQRVGSGTYGDVYKAKA*TQGACC 423
>20513
Length = 405
Score = 29.6 bits (65), Expect = 1.0, Method: Compositional matrix adjust.
Identities = 10/25 (40%), Positives = 16/25 (64%)
Frame = -1
Query: 205 DLLSKMLIYDPAKRISGKMALNHPY 229
D L+ ML +DP +R + +L HP+
Sbjct: 282 DFLAPMLEFDPEQRATAAQSLQHPW 208
>27546
Length = 426
Score = 29.6 bits (65), Expect = 1.2, Method: Compositional matrix adjust.
Identities = 9/33 (27%), Positives = 20/33 (60%)
Frame = -1
Query: 50 REISLLKELRHPNIVSLQDVLMQDSRLYLIFEF 82
RE+ +L L HPNI+ + +L + ++++ +
Sbjct: 333 RELEILTRLDHPNIIQIHSILQRGPKIFIFMRY 235
>28157
Length = 400
Score = 29.6 bits (65), Expect = 1.2, Method: Compositional matrix adjust.
Identities = 19/53 (35%), Positives = 31/53 (58%)
Frame = +3
Query: 30 VAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQDVLMQDSRLYLIFEF 82
VA+K R+ESE+E + ++E+ L + HPNIV L +D + L+ E+
Sbjct: 9 VAVK--RIESEQE--KKSFMQELKQLSRVSHPNIVCLYGAC-RDHPVCLVMEY 152
>21210
Length = 518
Score = 28.5 bits (62), Expect = 2.7, Method: Compositional matrix adjust.
Identities = 19/57 (33%), Positives = 27/57 (47%), Gaps = 4/57 (7%)
Frame = +3
Query: 112 YRSPEVL---LGSARYSTPVDIWSIGTIFAELATKK-PLFHGDSEIDQLFRIFRALG 164
Y +PE + S Y D+WS+G ELAT + P S DQL ++ R +
Sbjct: 18 YMAPERIDPRASSHGYDVRSDVWSLGITLMELATGRFPYRKWVSIFDQLQQVVRGVA 188
>17516
Length = 453
Score = 27.7 bits (60), Expect = 4.1, Method: Compositional matrix adjust.
Identities = 12/29 (41%), Positives = 17/29 (58%)
Frame = -3
Query: 112 YRSPEVLLGSARYSTPVDIWSIGTIFAEL 140
Y +PEVLL +Y D++S+ I EL
Sbjct: 421 YMAPEVLLQKGQYDMKADVYSLAIILWEL 335
>13305
Length = 549
Score = 27.7 bits (60), Expect = 4.5, Method: Compositional matrix adjust.
Identities = 11/38 (28%), Positives = 19/38 (50%)
Frame = +2
Query: 124 YSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFR 161
Y+T D+WS G + E+ T + ++ QLF +
Sbjct: 56 YTTQSDVWSFGVVLWEIFTLGGTPYSSTDTQQLFAFLK 169
>17806
Length = 433
Score = 27.3 bits (59), Expect = 5.8, Method: Compositional matrix adjust.
Identities = 16/51 (31%), Positives = 29/51 (56%), Gaps = 1/51 (1%)
Frame = +1
Query: 51 EISLLKELRHPNIVSLQDVLMQDSRLYLIFEFLSM-DLKKYLDSIPPGQYM 100
E++ +EL HPNIV L + + + ++ E ++ +LK+YL + Q M
Sbjct: 208 EVAPFRELDHPNIVRLLGQCTEMNPMLMLMECAALGNLKQYLRNHRHQQAM 360
>04852
Length = 1462
Score = 27.3 bits (59), Expect = 6.2, Method: Compositional matrix adjust.
Identities = 11/29 (37%), Positives = 17/29 (58%)
Frame = +1
Query: 112 YRSPEVLLGSARYSTPVDIWSIGTIFAEL 140
+ +PE L RY+T D+WS G + E+
Sbjct: 520 WMAPEALF-DMRYTTKSDVWSFGVVLWEI 603
>26052
Length = 562
Score = 26.9 bits (58), Expect = 6.5, Method: Compositional matrix adjust.
Identities = 11/27 (40%), Positives = 19/27 (70%)
Frame = -1
Query: 10 IGEGTYGVVYKGRHKTTGQVVAMKKIR 36
+G G++G V +HK TG+ +A+K I+
Sbjct: 367 LGVGSFGKVMALQHKDTGETLAVKNIQ 287
>00392
Length = 668
Score = 26.6 bits (57), Expect = 8.5, Method: Compositional matrix adjust.
Identities = 30/113 (26%), Positives = 45/113 (39%), Gaps = 6/113 (5%)
Frame = +3
Query: 51 EISLLKELRHPNIVSLQDVLMQDSR-----LYLIFEFL-SMDLKKYLDSIPPGQYMDSSL 104
E +LKEL+HPNIV D + + + L+ E + S LK YL
Sbjct: 81 EAEMLKELQHPNIVRFFDYWEEHNHRNRKVIILVTELMTSGTLKTYLKRFKKPN------ 242
Query: 105 VKVVTLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLF 157
VK++ W R +VL G ++ P+ H D + D +F
Sbjct: 243 VKILKNWCR--QVLKG---------------LYFLHTRTPPVIHRDLKCDNIF 350
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000222330 | hsapiens_gene_ensembl | Glycogen
synthase kinase-3 alpha (EC 2.7.11.26) (GSK-3 alpha).
[Source:Uniprot/SWISSPROT;Acc:P49840]
(483 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
32359 237 2e-69
05084 185 3e-47
01707 155 3e-38
01060 144 8e-35
14126 137 7e-33
01756 127 9e-30
29581 117 7e-27
04591 108 5e-24
28638 73 1e-21
04138 100 2e-21
32000 92 5e-19
03508 89 4e-18
13592 89 6e-18
00300 83 3e-16
23319 80 2e-15
18921 79 3e-15
12721 77 1e-14
09606 76 3e-14
03240 72 4e-13
15910 72 5e-13
18484 71 1e-12
06405 71 1e-12
30755 70 2e-12
13066 70 2e-12
01966 67 1e-11
19301 64 1e-10
26560 64 1e-10
12453 63 3e-10
09007 63 3e-10
31885 62 5e-10
01392 61 8e-10
12786 60 3e-09
01718 59 3e-09
03294 59 3e-09
13212 59 3e-09
14420 59 4e-09
27546 58 7e-09
18401 57 1e-08
18287 57 1e-08
27405 56 3e-08
17975 56 4e-08
07940 56 4e-08
26711 55 6e-08
31489 55 8e-08
21433 52 5e-07
14477 52 5e-07
19094 52 6e-07
19761 52 6e-07
21808 51 1e-06
14116 50 2e-06
04852 50 2e-06
21079 49 5e-06
11185 48 9e-06
16708 46 3e-05
00715 45 5e-05
28157 45 5e-05
11404 44 1e-04
07291 40 0.002
00638 40 0.003
16003 40 0.003
26009 39 0.004
01106 37 0.013
21800 37 0.022
25019 37 0.023
18996 35 0.048
36481 35 0.050
13078 35 0.064
02638 35 0.068
37602 34 0.13
00486 34 0.16
20152 33 0.24
29360 33 0.28
38560 33 0.29
18481 33 0.30
24241 31 1.4
17806 31 1.4
35032 30 2.6
>32359
Length = 928
Score = 237 bits (604), Expect(2) = 2e-69, Method: Compositional matrix adjust.
Identities = 110/132 (83%), Positives = 125/132 (94%)
Frame = -1
Query: 108 GQGPERSQEVAYTDIKVIGNGSFGVVYQARLAETRELVAIKKVLQDKRFKNRELQIMRKL 167
GQGP+R QEV+YTD KVIGNGSFGVVYQA+L +T ELVAIKKVLQDKRFKNRELQIMRKL
Sbjct: 457 GQGPDRPQEVSYTDAKVIGNGSFGVVYQAKLVDTSELVAIKKVLQDKRFKNRELQIMRKL 278
Query: 168 DHCNIVRLRYFFYSSGEKKDELYLNLVLEYVPETVYRVARHFTKAKLTIPILYVKVYMYQ 227
+H NIV+L++FFYSSGEKKDE++LNLVLEYVPETVYRVARH++K+K TIPILY+K+YMYQ
Sbjct: 277 EHQNIVKLKFFFYSSGEKKDEVFLNLVLEYVPETVYRVARHYSKSKQTIPILYIKLYMYQ 98
Query: 228 LFRSLAYIHSQG 239
LFRSLAYIHSQ
Sbjct: 97 LFRSLAYIHSQA 62
Score = 43.9 bits (102), Expect(2) = 2e-69, Method: Compositional matrix adjust.
Identities = 18/21 (85%), Positives = 20/21 (95%)
Frame = -3
Query: 239 GVCHRDIKPQNLLVDPDTAVL 259
GVCHRDIKPQNLL+DP+T VL
Sbjct: 65 GVCHRDIKPQNLLLDPETGVL 3
>05084
Length = 1324
Score = 185 bits (470), Expect = 3e-47, Method: Compositional matrix adjust.
Identities = 90/128 (70%), Positives = 100/128 (78%)
Frame = +2
Query: 320 FPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHPWTKVFKSRTPPEAIAL 379
PGDSGVDQLVEIIKVLGTPTREQIREMNPNY+EFKFPQIKAHPWTKVF+ RTPPEAI L
Sbjct: 2 LPGDSGVDQLVEIIKVLGTPTREQIREMNPNYSEFKFPQIKAHPWTKVFRPRTPPEAIQL 181
Query: 380 CSSLLEYTPSSRLSPLEACAHSFFDELRCLGTQXXXXXXXXXXXXXSAGELSIQPSLNAI 439
S LLEYTPS+R+ P+EACAH+FFDELR ++ + EL+I P LNA
Sbjct: 182 VSRLLEYTPSARIQPMEACAHAFFDELRDPASRLPNGRELPPLFSFTQMELAIAPQLNAS 361
Query: 440 LIPPHLRS 447
LIPPH RS
Sbjct: 362 LIPPHARS 385
>01707
Length = 757
Score = 155 bits (393), Expect = 3e-38, Method: Compositional matrix adjust.
Identities = 91/226 (40%), Positives = 129/226 (57%), Gaps = 7/226 (3%)
Frame = +1
Query: 119 YTDIKVIGNGSFGVVYQARLAETRELVAIKKVLQD------KRFKNRELQIMRKLDHCNI 172
Y I IG GS+GVV++ R ET +LVAIKK ++ K+ RE++++++L H N+
Sbjct: 70 YEKIGKIGEGSYGVVFKCRNKETSQLVAIKKFVESEDDPLIKKIAMREIRMLKQLKHPNL 249
Query: 173 VRLRYFFYSSGEKKDELYLNLVLEYVPETVYRVARHFTKAKLTIPILYVKVYMYQLFRSL 232
VRL F L+LV +YV T+ + + +P VK +YQ ++
Sbjct: 250 VRLIEVFRRKKR------LHLVFDYVDHTLLNELDRYPRG---LPEPMVKRIIYQTLLAV 402
Query: 233 AYIHSQGVCHRDIKPQNLLVDPDTAVLKLCDFGSAKQLVR-GEPNVSYICSRYYRAPELI 291
+ H HRD+KP+N+L+ V KLCDFG A+ L G+ Y+ +R+YRAPEL+
Sbjct: 403 NFCHQYNTIHRDVKPENILITRQGQV-KLCDFGFARILTGPGDEYTDYVATRWYRAPELL 579
Query: 292 FGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLG 337
G T Y +DVW+ GCV AELL GQ ++PG S VDQL I K LG
Sbjct: 580 VGDTQYGPPVDVWAIGCVFAELLTGQALWPGRSDVDQLHLIRKTLG 717
>01060
Length = 1800
Score = 144 bits (363), Expect = 8e-35, Method: Compositional matrix adjust.
Identities = 98/303 (32%), Positives = 161/303 (53%), Gaps = 19/303 (6%)
Frame = +1
Query: 120 TDIKVIGNGSFGVVYQARLAETRELVAIKKVLQDKRFKN----------RELQIMRKLDH 169
TD + IG G++GVVY+ R T +A+KK+ R + RE+ ++R+L H
Sbjct: 82 TDFQKIGEGTYGVVYKCRHRATGRKLAMKKI----RLRGSEDGVPSSAIREIAMLRELRH 249
Query: 170 CNIVRLRYFFYSSGEKKDELYLNLVLEYVPETVYRVARHFTKAKLTIPILYVKVYMYQLF 229
NIV L +DE L LV E++ + F + + + VK Y++Q+
Sbjct: 250 TNIVCLEDVIM-----EDE-RLFLVFEFLSMDLKMYIDKFPEG-VVLDRRLVKSYVFQIV 408
Query: 230 RSLAYIHSQGVCHRDIKPQNLLVDPDTAVLKLCDFGSAKQLVRGEPNVSY---ICSRYYR 286
+ + H + + HRD+KPQNLL++ T +K+ DFG A+ P +Y + + +YR
Sbjct: 409 TGIXFCHQRRIVHRDLKPQNLLIN-HTGAIKIADFGMARTF--ALPVRAYTHEVVTLWYR 579
Query: 287 APELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIRE 346
APE++ GA+ Y++ +DVWS G + A++L+ PIF GDS +DQL +I +++GTPT + E
Sbjct: 580 APEILMGASKYSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPE 759
Query: 347 MN--PNYTEFKFPQIKAHPWTKVFKSRTPPEAIALCSSLLEYT----PSSRLSPLEACAH 400
+ P + FP W + S T + +L L+E T P+ R+S + H
Sbjct: 760 FHKLPAFNGM-FPL-----WKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQH 921
Query: 401 SFF 403
++F
Sbjct: 922 AYF 930
>14126
Length = 1265
Score = 137 bits (346), Expect = 7e-33, Method: Compositional matrix adjust.
Identities = 103/327 (31%), Positives = 163/327 (49%), Gaps = 29/327 (8%)
Frame = +3
Query: 114 SQEVAYTDIKVIGNGSFGVVYQAR-LAETRELVAIKKVLQDKRFKN----------RELQ 162
S E Y ++ VIGNG++G VY+AR L E VA+K++ R N RE+
Sbjct: 180 STEQKYEEVAVIGNGAYGTVYKARDLRNQGEFVAMKRI----RLNNTEEGMPMMAIREIS 347
Query: 163 IMRKLD---HCNIVRLRYFFYSSGEKKDELYLNLVLEYVPETVYRVARHFTKAKLTIPIL 219
++++L+ H N+VRL +++ + E+ LNLV EY+ + +A + AK P L
Sbjct: 348 MLKQLEQYEHPNVVRLLDVSHNTITDR-EIRLNLVFEYIE---HDLATYL--AKCPSPGL 509
Query: 220 ---YVKVYMYQLFRSLAYIHSQGVCHRDIKPQNLLVDPDTAVLKLCDFGSAKQLVRGEPN 276
+K M QL + ++HS + HRD+KPQNLL+ D LKL DFG A+
Sbjct: 510 GPDRIKDLMLQLLNGVDFLHSNRIVHRDLKPQNLLISKD-GRLKLADFGLARIYSFHMAL 686
Query: 277 VSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVL 336
+ + + +YR+PE++ A +Y +S+D+WS GC+ AEL + +F G S DQL +I +V+
Sbjct: 687 TTVVVTLWYRSPEVLMQA-EYGTSVDIWSCGCIFAELFTRRALFKGSSEFDQLKKIFEVI 863
Query: 337 GTP-----------TREQIREMNPNYTEFKFPQIKAHPWTKVFKSRTPPEAIALCSSLLE 385
G P R R P + P++ P+A L +L
Sbjct: 864 GLPPAGDWPEGVSVHRNSFRPTPPVPLQTLVPEMD-------------PQAKDLMEKMLV 1004
Query: 386 YTPSSRLSPLEACAHSFF-DELRCLGT 411
+ R+S E+ H + D+L + T
Sbjct: 1005FKSGRRISSRESLLHPYLRDDLDSIRT 1085
>01756
Length = 1858
Score = 127 bits (320), Expect = 9e-30, Method: Compositional matrix adjust.
Identities = 80/243 (32%), Positives = 129/243 (53%), Gaps = 14/243 (5%)
Frame = -3
Query: 114 SQEVAYTDIKVIGNGSFGVVYQARLAETRELVAIKKVLQDKRFKN------RELQIMRKL 167
++ Y + IG G+FG V++AR +T+++VA+KKVL D + RE++I++ L
Sbjct: 1751 DEDAKYEKLAKIGQGTFGEVFKARCKKTKQVVAMKKVLMDNEKEGFPITALREIKILQLL 1572
Query: 168 DHCNIVRLRYF----FYSSGEKKDELYLNLVLEYVPETVYRVARHFTKAKLTIPILYVKV 223
+H N+V L S+ K YL V E+ + +A + + + +K
Sbjct: 1571 NHENVVDLIEICSTKATSANRYKSMFYL--VFEFCE---HDLAGLLSNMSVVFNLPEIKE 1407
Query: 224 YMYQLFRSLAYIHSQGVCHRDIKPQNLLVDPDTAVLKLCDFGSAKQLVRG--EPN--VSY 279
M QL L YIH + HRD+K N+L+ VLKL DFG A+ +PN +
Sbjct: 1406 VMKQLMNGLYYIHRNKILHRDMKAANILIT-KQGVLKLADFGLARAFSVNLRQPNRYTNR 1230
Query: 280 ICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTP 339
+ + +YR PEL+ G +Y+++ID W AGC++AE+ PI G + +QL I ++ G+
Sbjct: 1229 VVTLWYRPPELLLGDRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQNQLTLITQLCGSI 1050
Query: 340 TRE 342
T E
Sbjct: 1049 TPE 1041
>29581
Length = 1278
Score = 117 bits (294), Expect = 7e-27, Method: Compositional matrix adjust.
Identities = 81/255 (31%), Positives = 135/255 (52%), Gaps = 12/255 (4%)
Frame = -2
Query: 163 IMRKLDHCNIVRLRYFFYSSGEKKDELYLNLVLEYVPETVYRVARH----FTKAKLTIPI 218
+ L H NIV+L+ G+ D L+L V+EY + + + + F++++
Sbjct: 1196 FLLNLRHQNIVQLQEVVV--GKSLDSLFL--VMEYCEQDLASLLDNMPAPFSESQ----- 1044
Query: 219 LYVKVYMYQLFRSLAYIHSQGVCHRDIKPQNLLVDPDTAVLKLCDFGSAKQLVRGE-PNV 277
VK + QL + L Y+H + HRD+K NLL+ D +K+ DFG A+ + + P
Sbjct: 1043 --VKCIVLQLLKGLRYLHEAFIIHRDLKVSNLLMT-DKGCVKIADFGLARNYGKPQKPMT 873
Query: 278 SYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLG 337
+ + +YRAPEL+FG+ ++++ID+WSAGC+L ELL +P+ PG S + Q+ I+++LG
Sbjct: 872 PKVVTLWYRAPELLFGSKTHSTAIDMWSAGCILGELLGHKPLMPGRSDLQQIELIMELLG 693
Query: 338 TPTREQIREMNPNYTEF-KFPQ--IKAHPWTKVFKSRTPP----EAIALCSSLLEYTPSS 390
TP + P +++ F Q +K P+ + T P I L + L Y P
Sbjct: 692 TPN----DTIWPGFSQLPAFEQFTLKKQPYNNL--RHTFPWLSESGIRLLNGLFMYHPQK 531
Query: 391 RLSPLEACAHSFFDE 405
R + + HS+F E
Sbjct: 530 RATAEDCLEHSYFKE 486
>04591
Length = 1117
Score = 108 bits (270), Expect = 5e-24, Method: Compositional matrix adjust.
Identities = 74/252 (29%), Positives = 120/252 (47%), Gaps = 7/252 (2%)
Frame = -2
Query: 159 RELQIMRKLDHCNIVRLRYFFYSSG----EKKDELYLNLVLEYVPETVYRVARHFTKAKL 214
RE++I+++L+H N+V+L+ ++ K YL + EY Y +A ++
Sbjct: 1074 REIKILQQLEHENVVQLQEICHTQAGPYNRYKSTFYL--IFEYCD---YDLAGLLNNLRV 910
Query: 215 TIPILYVKVYMYQLFRSLAYIHSQGVCHRDIKPQNLLVDPDTAVLKLCDFGSAKQLVRGE 274
+ K M QL L YIH++ + HRDIK N+L+ D VLKL DFG ++ V+ +
Sbjct: 909 KFSLADKKNLMSQLLNGLFYIHTKQILHRDIKAANILLTRD-GVLKLADFGLSRPWVKSK 733
Query: 275 PNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIK 334
+ + + +YR PEL+ G +Y ID+W GC++AE+ +P+ G S QL I
Sbjct: 732 RLTNRVVTLWYRPPELLLGEREYGPEIDMWGVGCIMAEMWSRKPLMQGRSEQHQLSLITD 553
Query: 335 VLGTPTREQIREMNP--NYTEFKFPQIKAHPWT-KVFKSRTPPEAIALCSSLLEYTPSSR 391
+ G+ E + Y + PQ K ++ E L L P R
Sbjct: 552 LCGSLNAEVWPGVTKLELYGKLDLPQGKPRKVKERMLDLLKNKEGAELIDIFLRLDPGQR 373
Query: 392 LSPLEACAHSFF 403
++ A +H FF
Sbjct: 372 MNCDNALSHDFF 337
>28638
Length = 1458
Score = 72.8 bits (177), Expect(3) = 1e-21, Method: Compositional matrix adjust.
Identities = 39/98 (39%), Positives = 62/98 (63%), Gaps = 3/98 (3%)
Frame = -1
Query: 224 YMYQLFRSLAYIHS--QGVCHRDIKPQN-LLVDPDTAVLKLCDFGSAKQLVRGEPNVSYI 280
+ QL +L ++ + + H D+KP+N LL +P + +K+ DFGS+ QL G+ YI
Sbjct: 822 FAQQLCTALLFLATPEMNIIHCDLKPENILLCNPKRSAIKIVDFGSSCQL--GQRIYQYI 649
Query: 281 CSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQP 318
SR+YR+PE++ G Y +ID+WS GC+L E+ G+P
Sbjct: 648 QSRFYRSPEVLLGV-PYDLAIDMWSLGCILVEMHTGEP 538
Score = 35.0 bits (79), Expect(3) = 1e-21, Method: Compositional matrix adjust.
Identities = 32/94 (34%), Positives = 47/94 (50%), Gaps = 10/94 (10%)
Frame = -3
Query: 124 VIGNGSFGVVYQARLAETRELVAIKKVLQDKRFKNRE------LQIMRKLDHCN---IVR 174
+IG GSFG V +A +E VAIK + K F N+ L++M + D N IVR
Sbjct: 1126 LIGKGSFGQVVKAYDHGDQEQVAIKIIKNKKPFLNQAQIEVKLLELMNRHDADNXYYIVR 947
Query: 175 L-RYFFYSSGEKKDELYLNLVLEYVPETVYRVAR 207
L R+F + + +L LV E + +Y + R
Sbjct: 946 LKRHFMFRN-------HLCLVFELLSYNLYDLLR 866
Score = 33.5 bits (75), Expect(3) = 1e-21, Method: Compositional matrix adjust.
Identities = 30/122 (24%), Positives = 48/122 (39%), Gaps = 34/122 (27%)
Frame = -2
Query: 316 GQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFK-FPQIKAHPW----TKVFKS 370
G P+F G + DQ+++I++VLG P R + + F P P K +KS
Sbjct: 545 GNPLFAGSNEFDQMMKIVEVLGVPPRHILDQAQKTRKYFDLLPDGTYAPKKPRDNKKYKS 366
Query: 371 RT----------------------PPEAIA-------LCSSLLEYTPSSRLSPLEACAHS 401
+ P +A L +L++ P +R+SP A H+
Sbjct: 365 PSSRKLHEVLGAEKGGPGGRRMGEPGHTVADYLKFKDLILRMLDFDPKTRISPYYALQHN 186
Query: 402 FF 403
FF
Sbjct: 185 FF 180
>04138
Length = 800
Score = 99.8 bits (247), Expect = 2e-21, Method: Compositional matrix adjust.
Identities = 64/185 (34%), Positives = 95/185 (51%), Gaps = 13/185 (7%)
Frame = +1
Query: 232 LAYIHSQGVCHRDIKPQNLLVDPDTAVLKLCDFGSAKQLVRG--EPN--VSYICSRYYRA 287
L YIH + HRD+K N+L+ VLKL DFG A+ +PN + + + +YR
Sbjct: 52 LYYIHRNKILHRDMKAANILITKQ-GVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRP 228
Query: 288 PELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREM 347
PEL+ G +Y+++ID W AGC++AE+ PI G + +QL I ++ G+ T E+
Sbjct: 229 PELLLGDRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQNQLTLITQLCGSIT----PEV 396
Query: 348 NPNYTEFK-FPQIK---AHPWTKVFKSR-----TPPEAIALCSSLLEYTPSSRLSPLEAC 398
P T+ + QIK A + + R P + L LL+ PS R+S EA
Sbjct: 397 WPGVTQLSMYHQIKGALAAGRKNIIRDRFARILKDPYGLDLFERLLKMDPSQRISADEAL 576
Query: 399 AHSFF 403
H FF
Sbjct: 577 NHDFF 591
>32000
Length = 644
Score = 91.7 bits (226), Expect = 5e-19, Method: Compositional matrix adjust.
Identities = 50/161 (31%), Positives = 88/161 (54%), Gaps = 9/161 (5%)
Frame = -1
Query: 256 TAVLKLCDFGSAKQLVRGEPNVSY---ICSRYYRAPELIFGATDYTSSIDVWSAGCVLAE 312
TA +K+ DFG A+ V G P +Y + + +YRAPE++ G Y+ +D+WS GC+ E
Sbjct: 581 TAKMKIADFGLAR--VFGLPVRTYTHEVITLWYRAPEILLGCRFYSVPVDIWSLGCIFVE 408
Query: 313 LLLGQPIFPGDSGVDQLVEIIKVLGTPTRE------QIREMNPNYTEFKFPQIKAHPWTK 366
++ + +FPGDS +DQL I + LGTP + ++ + P + ++ ++ T
Sbjct: 407 MMTRRALFPGDSEIDQLYRIFRTLGTPDEKVWPGVSKLPDYKPTFPKWPLKNLE----TV 240
Query: 367 VFKSRTPPEAIALCSSLLEYTPSSRLSPLEACAHSFFDELR 407
V S+ + L +L Y P+ R+S A H +F++++
Sbjct: 239 VSLSKV---GLDLLKRMLTYNPNRRISARSAMRHPYFNDMK 126
>03508
Length = 1463
Score = 89.0 bits (219), Expect = 4e-18, Method: Compositional matrix adjust.
Identities = 45/131 (34%), Positives = 75/131 (57%), Gaps = 2/131 (1%)
Frame = +1
Query: 193 LVLEYVPETVYRVARHFTKAKLTIPILYVKVYMYQLFRSLAYIHSQGVCHRDIKPQNLLV 252
L+ E+V T F + T ++ Y+Y+L ++L + HS G+ HRD+KP N+++
Sbjct: 811 LIFEHVNNT------DFKQLYQTFTDYDIRFYLYELMKALDFCHSMGIMHRDVKPHNVMI 972
Query: 253 DPDTAVLKLCDFGSAKQLVRG-EPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLA 311
D + L+L D+G A+ G E NV + SRY++ PEL+ Y S+D+WS GC+ A
Sbjct: 973 DHENKKLRLIDWGLAEFYHPGMEYNVR-VASRYFKGPELLLDYQMYDYSLDMWSLGCMFA 1149
Query: 312 ELLL-GQPIFP 321
++ +P+ P
Sbjct: 1150SMIFRKEPLLP 1182
Score = 45.4 bits (106), Expect = 5e-05, Method: Compositional matrix adjust.
Identities = 35/111 (31%), Positives = 49/111 (44%), Gaps = 10/111 (9%)
Frame = +2
Query: 303 VWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPT------REQIREMNPNYTEFKF 356
VW+A C+ A P F G DQLV I KVLGT + QI +++P + +
Sbjct: 1130 VWAA-CLPA*SSGKSPFFHGHDNYDQLVRIAKVLGTDDLYGYIEKYQI-DLDPRFNDI-L 1300
Query: 357 PQIKAHPWTKVFKSRT----PPEAIALCSSLLEYTPSSRLSPLEACAHSFF 403
+ W + S PEA+ LL Y + RL+ EA H +F
Sbjct: 1301 GRHSRKRWERFVHSENQHLISPEALDFLDKLLRYDHNERLTAREAMDHPYF 1453
>13592
Length = 980
Score = 88.6 bits (218), Expect = 6e-18, Method: Compositional matrix adjust.
Identities = 66/207 (31%), Positives = 102/207 (49%), Gaps = 14/207 (6%)
Frame = +2
Query: 125 IGNGSFGVVYQARLAETRELVAIKKVL----QDKRFKN--RELQIMRKLDHCNIVRLRYF 178
IG G FG VY A T EL+A+K++ + + KN EL+I+ + H N+VR
Sbjct: 8 IGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETRALKNVAEELKILEGIKHKNLVR---- 175
Query: 179 FYSSGEKKDELYLNLVLEYVPETVYRVARHFTKAKLTIPILYVKVYMYQLFRSLAYIHSQ 238
+Y ++EL + +E E T +P + + QL +A +H
Sbjct: 176 YYGIEVHREELLI--FMELCSEGTLESLVELTGG---LPEALSRRFTAQLLSGVAELHKH 340
Query: 239 GVCHRDIKPQNLLVDPDTAVLKLCDFGSAKQL-----VRGEPNVSYICSRYYRAPELIFG 293
G+ HRDIK N+ + + LKL DFGSA ++ V GE Y+ ++ Y APE +F
Sbjct: 341 GIVHRDIKTANIFLVDGSNSLKLGDFGSAVKIQAHTTVPGELQ-GYVGTQAYMAPE-VFT 514
Query: 294 ATD---YTSSIDVWSAGCVLAELLLGQ 317
T+ + D+WS GCV+ E+ G+
Sbjct: 515 KTNSDGHGRLADIWSVGCVVVEMASGK 595
>00300
Length = 2318
Score = 82.8 bits (203), Expect = 3e-16, Method: Compositional matrix adjust.
Identities = 63/207 (30%), Positives = 103/207 (49%), Gaps = 14/207 (6%)
Frame = -1
Query: 125 IGNGSFGVVYQARLAETRELVAIKKV------LQDKRFKNRELQIMRKLDHCNIVRLRYF 178
IG G FG VY A T EL+A+K++ LQ R E++I + H N+V+
Sbjct: 1634 IGEGQFGKVYTAVNMSTGELMALKEMKFQPNDLQQLREMCDEIKIFEGIQHENLVK---- 1467
Query: 179 FYSSGEKKDELYLNLVLEYVPETVYRVARHFTKAKLTIPILYVKVYMYQLFRSLAYIHSQ 238
+Y KDE+ + +EY A AK+ +P ++ Y ++ ++ ++H
Sbjct: 1466 YYGVEVHKDEMLM--FMEYCDTGTIEEA-----AKMGLPEYLIRRYTREIVLAVNHLHEN 1308
Query: 239 GVCHRDIKPQNLLVDPDTAVLKLCDFGSAKQL-----VRGEPNVSYICSRYYRAPELIFG 293
+ HRDIK N+ + + V KL DFG + +L + GE + + + + Y APE +F
Sbjct: 1307 SIVHRDIKGANIFLTSNGHV-KLGDFGCSVKLKSHTTMPGEFH-NLVGTTAYMAPE-VFT 1137
Query: 294 ATD---YTSSIDVWSAGCVLAELLLGQ 317
D Y + D+WS GCV+ E+ G+
Sbjct: 1136 QNDQGGYGRAADIWSLGCVVIEMATGK 1056
>23319
Length = 2235
Score = 80.5 bits (197), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 48/119 (40%), Positives = 66/119 (55%), Gaps = 3/119 (2%)
Frame = +3
Query: 291 IFGATDYTSSIDVWSAGCVLAELL-LGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMN- 348
++ A Y++SID+WSAGC+ AEL G+P+FPG+ DQL I K+LGTPT +Q M
Sbjct: 9 VYXAKMYSTSIDMWSAGCIFAELANAGRPLFPGNDDDDQLKRIFKLLGTPTEDQWPGMTQ 188
Query: 349 -PNYTEFKFPQIKAHPWTKVFKSRTPPEAIALCSSLLEYTPSSRLSPLEACAHSFFDEL 406
PNY F + W +V + + L LL PS R+S EA H +F +L
Sbjct: 189 LPNYRMFPMYHVTTT-WQQVV-PKLNSKGRDLLQCLLVCCPSDRMSADEALQHPYFADL 359
>18921
Length = 697
Score = 79.3 bits (194), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 63/198 (31%), Positives = 102/198 (51%), Gaps = 4/198 (2%)
Frame = +2
Query: 125 IGNGSFGVVYQARLAETRELVAIKKVLQDKRFKN--RELQIMRKLDHCNIVRLRYFFYSS 182
+G GS+G V+++ ET +++AIK+V D + +E+ IM++ D IV+ +Y S
Sbjct: 53 LGEGSYGSVFKSLHKETGQVLAIKQVPVDTDLQEIIKEISIMQQCDSKYIVK----YYGS 220
Query: 183 GEKKDELYLNLVLEYV-PETVYRVARHFTKAKLTIPILYVKVYMYQLFRSLAYIHSQGVC 241
K +L++ V+EY +V + R K + I + +Y + L Y+HS+
Sbjct: 221 YFKNTDLWI--VMEYCGAGSVSDIMRLRNKTLVEREIATI---LYYTLKGLXYLHSRRKI 385
Query: 242 HRDIKPQNLLVDPDTAVLKLCDFGSAKQLVRG-EPNVSYICSRYYRAPELIFGATDYTSS 300
HRDIK N+L++ + KL DFG A QL + I + Y+ APE+I Y
Sbjct: 386 HRDIKAGNILLNNEGHA-KLADFGVAGQLTDTMAKRNTVIGTPYWMAPEVI-QEIGYDCV 559
Query: 301 IDVWSAGCVLAELLLGQP 318
D+WS G E+ G+P
Sbjct: 560 ADIWSLGITALEMAEGKP 613
>12721
Length = 821
Score = 77.0 bits (188), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 63/207 (30%), Positives = 106/207 (51%), Gaps = 7/207 (3%)
Frame = +1
Query: 121 DIKVIGNGSFGVVYQARLAETRELVAIKKVLQDKRFKNR------ELQIMRKLDHCNIVR 174
D IG GS G+V A + R++ A+KK+ D R + R E+ +MR H NIV
Sbjct: 100 DFMKIGEGSTGIVCIATSRDGRQM-AVKKM--DLRKQQRRELLFNEVVVMRDYHHPNIVE 270
Query: 175 LRYFFYSSGEKKDELYLNLVLEYVPETVYRVARHFTKAKLTIPILYVKVYMYQLFRSLAY 234
+ Y+S DEL++ V+E++ + T ++ + + ++LA+
Sbjct: 271 M----YNSYLVNDELWV--VMEFMEGGA--LTDIVTNNRMDE--VQIATVCRACLKALAF 420
Query: 235 IHSQGVCHRDIKPQNLLVDPDTAVLKLCDFGSAKQLVRG-EPNVSYICSRYYRAPELIFG 293
+H+ GV HRDIK ++L+ D V KL DFG Q+ + + S + + Y+ APE+I
Sbjct: 421 LHANGVIHRDIKSDSILLSHDGKV-KLXDFGFCAQVTQDLQKRKSLVGTPYWMAPEVI-S 594
Query: 294 ATDYTSSIDVWSAGCVLAELLLGQPIF 320
Y +D+WS G ++ E++ +P F
Sbjct: 595 RLPYGPEVDIWSLGIMVMEMIDAEPPF 675
>09606
Length = 1300
Score = 75.9 bits (185), Expect = 3e-14, Method: Compositional matrix adjust.
Identities = 77/306 (25%), Positives = 132/306 (43%), Gaps = 27/306 (8%)
Frame = -3
Query: 125 IGNGSFGVVYQARLAETRELVAIKKVLQDKRFK-NRELQIMRKLDHCNIVRLRYFFYSSG 183
+G G ++Y+ R T VAI + + KR + +++ + H N+V+ ++ +S
Sbjct: 1091 LGKGEHSIIYKGRRKGTINFVAIHCIEKCKRPEVTNTVRMTHDISHPNVVQFHEWYETSN 912
Query: 184 EKKDELYLNLVLEYVPETVYRVARHFTKAKLTIPILYVKVYMYQLFRSLAYIHSQGVCHR 243
+L LV+E T +A + +P ++ + L L YIHS G+
Sbjct: 911 ------HLWLVVELC--TGGSLADILAQDH-HLPETSIRDFGIHLVTGLHYIHSLGILFH 759
Query: 244 DIKPQNLLVDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRY------------------- 284
D++P +L+D + VLK DFG +K V GE N+ + ++
Sbjct: 758 DLRPSKVLLD-TSGVLKFADFGLSK--VEGE-NLEELFFKFAEAGDQWNIQSAEEMMKQV 591
Query: 285 -------YRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLG 337
Y APE+ GA S D+W+ GCV E+ G P F G++ +I
Sbjct: 590 PTSGSPTYMAPEVFQGAEPSIMS-DLWALGCVFYEMFSGHPPFLGET-----YDI----- 444
Query: 338 TPTREQIREMNPNYTEFKFPQIKAHPWTKVFKSRTPPEAIALCSSLLEYTPSSRLSPLEA 397
T++++ EF P++K ++ PE + L SLL+ + RLS
Sbjct: 443 --TKDKVLN-----KEFPLPKVKG----SRLSAKPSPEFLNLLESLLQKDSTRRLSWASL 297
Query: 398 CAHSFF 403
H+F+
Sbjct: 296 VKHAFW 279
>03240
Length = 1683
Score = 72.4 bits (176), Expect = 4e-13, Method: Compositional matrix adjust.
Identities = 68/270 (25%), Positives = 111/270 (41%), Gaps = 55/270 (20%)
Frame = -3
Query: 119 YTDIKVIGNGSFGVVYQARLAETRELVAIKKVLQDKRFKNR-------ELQIMRKLDHCN 171
+ IK +G G+FG V R +T L A+K + + K E I+ + D+
Sbjct: 1285 FEKIKTLGVGAFGEVSLCRKNDTGMLYAMKTLRKSDVLKRNQVAHVKAERDILAEADNEW 1106
Query: 172 IVRLRYFFYSSGEKKDELYLNLVLEYVPETVYRVARHFTKAKLTIPIL---YVKVYMYQL 228
+V+L Y F +D YL V++YVP + + IL + Y+ +L
Sbjct: 1105 VVKLYYSF------QDHNYLYFVMDYVP------GGDLMGLLIRMEILDEPLARFYVAEL 962
Query: 229 FRSLAYIHSQGVCHRDIKPQNLLVDPDTAVLKLCDFG---------SAKQLVRGEPNV-- 277
+++ +H G HRDIKP N+L+D + + KL DFG ++K R +
Sbjct: 961 VQAIESVHRMGFIHRDIKPDNILIDRNGHI-KLTDFGLCTGFRWTHNSKYYQRDGTHARQ 785
Query: 278 ----------------------------------SYICSRYYRAPELIFGATDYTSSIDV 303
S + + Y APE++ YTS D
Sbjct: 784 DSMEVKCQLDEQCQCEILKPLERRRKREQRCLAHSLVGTPNYIAPEVLSRLGGYTSVCDW 605
Query: 304 WSAGCVLAELLLGQPIFPGDSGVDQLVEII 333
WS G +L E+L+G P F ++ + ++I
Sbjct: 604 WSVGVILFEMLVGHPPFYANTPAETQYKVI 515
>15910
Length = 1361
Score = 72.0 bits (175), Expect = 5e-13, Method: Compositional matrix adjust.
Identities = 54/174 (31%), Positives = 85/174 (48%), Gaps = 3/174 (1%)
Frame = +2
Query: 227 QLFRSLAYIHSQGVCHRDIKPQNLLVD--PDTAVLKLCDFGSAKQLVRGEPNVSYICSR- 283
+ + YIH+ GV HRD+KP+NLL + D + LKL DFG ++ ++ E +S +C
Sbjct: 488 DILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLADFGLSR-IIEPEVQMSTVCGTP 664
Query: 284 YYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQ 343
Y APE++ G YT S+D+WS G + LL G F ++ + +IIK
Sbjct: 665 GYCAPEVLKG-DKYTPSVDMWSVGVIAYILLCGYEPFFAENEFEMYRKIIK--------- 814
Query: 344 IREMNPNYTEFKFPQIKAHPWTKVFKSRTPPEAIALCSSLLEYTPSSRLSPLEA 397
E+KF + W+++ ++ A + LL P RL+ EA
Sbjct: 815 --------GEYKFDE---EYWSEISEN-----AKDVVRKLLVIDPKKRLTATEA 928
>18484
Length = 635
Score = 70.9 bits (172), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 53/195 (27%), Positives = 91/195 (46%), Gaps = 1/195 (0%)
Frame = +1
Query: 200 ETVYRVARHFTKAKLTIPILYVKVYMYQLFRSLAYIHSQGVCHRDIKPQNLLVDPDTAVL 259
+ +YR+ + + K P+ Y ++ L ++H QG+ +RD+K N+++D + +
Sbjct: 1 DLMYRIQQ---EGKFKEPV--AAFYAAEIAVGLFFLHDQGIIYRDLKLDNVMLDSEGHI- 162
Query: 260 KLCDFGSAKQLVRGEPNVSYICSR-YYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQP 318
K+ DFG K+ + G+ C Y APE++ Y+ S+D W+ G +L E+L GQP
Sbjct: 163 KIADFGMCKEGMTGDATTRTFCGTPDYIAPEIVL-YQPYSKSVDWWAYGVLLFEMLAGQP 339
Query: 319 IFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHPWTKVFKSRTPPEAIA 378
F G+ D+L I + N +Y P+ + EA++
Sbjct: 340 PFDGED-EDELF-----------SSITDHNVSY-----PKAMSR------------EAVS 432
Query: 379 LCSSLLEYTPSSRLS 393
LC LL P+ RL
Sbjct: 433 LCKGLLMKNPTKRLG 477
>06405
Length = 1965
Score = 70.9 bits (172), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 65/230 (28%), Positives = 117/230 (50%), Gaps = 14/230 (6%)
Frame = +1
Query: 107 LGQGPERSQ-EVAYTDIKV---IGNGSFGVVYQARLAETRELVAIKKVLQDKRFKN---R 159
G PE + E+ T+I + +G G +G VY+A ++VA+K + +D N
Sbjct: 217 FGVSPEPDRWEIERTEIAMKHRLGGGQYGDVYEAMWKRYNKIVAVKTLKEDTMALNDFLE 396
Query: 160 ELQIMRKLDHCNIVRLRYFFYSSGEKKDELYLNLVLEYVPE-TVYRVARHFTKAKLTIPI 218
E IM+++ H N+V+L G E +V E++P + R T+ +
Sbjct: 397 EAAIMKEMKHPNLVQLL------GVCTREPPFYIVTEFMPHGNLLDYLRSSTREENGPTA 558
Query: 219 LYVKVYMY-QLFRSLAYIHSQGVCHRDIKPQNLLVDPDTAVLKLCDFGSAKQLVRGEPNV 277
L +YM Q+ +AY+ ++ HRD+ +N LV D+ ++K+ DFG A+ L++ +
Sbjct: 559 L---MYMATQIASGMAYLETKNFIHRDLAARNCLVA-DSNMVKVADFGLAR-LMKDDTYT 723
Query: 278 SYICSRY---YRAPE-LIFGATDYTSSIDVWSAGCVLAEL-LLGQPIFPG 322
++I +++ + APE L F +++ D+W+ G +L EL G +PG
Sbjct: 724 AHIGAKFPIKWTAPEGLAFNR--FSTRSDIWAFGVLLWELATYGMSPYPG 867
>30755
Length = 1137
Score = 70.1 bits (170), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 56/189 (29%), Positives = 86/189 (45%), Gaps = 7/189 (3%)
Frame = +2
Query: 222 KVYMYQLFRSLAYIHSQGVCHRDIKPQNLLVDPDTAVLKLCDFGSAKQ-LVRGEPNVSYI 280
+ Y ++ +L Y+HSQG+ +RD+K +NLL+D D + K+ DFG K+ + G ++
Sbjct: 41 RFYGAEIISALGYLHSQGIIYRDLKLENLLLDKDGHI-KVADFGLCKEDITYGRTTKTFC 217
Query: 281 CSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQ-PIFPGDSGVDQLVEIIKVLGTP 339
+ Y APE + DY ++D W G V+ E++ G+ P + D D L +I V
Sbjct: 218 GTPEYLAPE-VLDDNDYGRAVDWWGTGVVMYEMICGRLPFYNRDH--DVLFTLILV---- 376
Query: 340 TREQIREMNPNYTEFKFPQIKAHPWTKVFKSRTPPEAIALCSSLLEYTPSSRLSP----- 394
+ KFP+ EA +L S LL P +RL
Sbjct: 377 ------------EDVKFPR------------NITDEAKSLLSGLLAKDPRNRLGGGQDDV 484
Query: 395 LEACAHSFF 403
E AH FF
Sbjct: 485 KEIQAHPFF 511
>13066
Length = 551
Score = 69.7 bits (169), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 60/199 (30%), Positives = 93/199 (46%), Gaps = 15/199 (7%)
Frame = +3
Query: 124 VIGNGSFGVVYQARLAETRELVAIKKVLQD--KRFKNRELQIMRKLDHCNIVRLR----- 176
V+ +G+F Y + +++ +K D ++F REL ++ KLDH I+++
Sbjct: 12 VVVHGTFNDGYGRNIKLACKIIDKEKAPVDFVEKFFPRELDLLTKLDHPYIIQIHSILQR 191
Query: 177 ----YFFYSSGEKKDELYLNLVLEYVPETVYRVARHFTKAKLTIPILYVKVYMYQLFRSL 232
+ F E+ D +L Y+ E F K K K++ YQ+ +L
Sbjct: 192 XPKNFIFMRFAERGD------LLTYIQEV------GFVKEKQA------KIWFYQMTTAL 317
Query: 233 AYIHSQGVCHRDIKPQNLLVDPDTAVLKLCDFGSAKQLV--RGEPNVS--YICSRYYRAP 288
Y+HS V HRD+K +N+L+ V KL DFG A + GE +S Y S Y AP
Sbjct: 318 NYLHSYDVAHRDLKCENILLSSHFNV-KLADFGFACACITESGEKYMSRTYCGSAAYAAP 494
Query: 289 ELIFGATDYTSSIDVWSAG 307
E+++GA D WS G
Sbjct: 495 EIVYGAPYAPKVADAWSLG 551
>01966
Length = 1735
Score = 67.4 bits (163), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 47/154 (30%), Positives = 80/154 (51%), Gaps = 3/154 (1%)
Frame = -1
Query: 159 RELQIMRKLDHCNIVRLRYFFYSSGEKKDELYLNLVLEYVPETVYRVARHFTKAKLTIPI 218
RE+ ++R+L H NIV L +DE L LV E++ + F + + +
Sbjct: 1567 REIAMLRELRHTNIVCLEDVIM-----EDE-RLFLVFEFLSMDLKMYIDKFPEG-VVLDR 1409
Query: 219 LYVKVYMYQLFRSLAYIHSQGVCHRDIKPQNLLVDPDTAVLKLCDFGSAKQLVRGEPNVS 278
VK Y++Q+ + + H + + HRD+KPQNLL++ T +K+ DFG A+ P +
Sbjct: 1408 RLVKSYVFQIVTGINFCHQRRIVHRDLKPQNLLIN-HTGAIKIADFGMARTF--ALPVRA 1238
Query: 279 Y---ICSRYYRAPELIFGATDYTSSIDVWSAGCV 309
Y + + +YRAPE++ G S+ W+ G +
Sbjct: 1237 YTHEVVTLWYRAPEILMGP---QSTPPXWTCGAL 1145
Score = 67.0 bits (162), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 42/129 (32%), Positives = 67/129 (51%), Gaps = 6/129 (4%)
Frame = -3
Query: 281 CSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPT 340
C P GA+ Y++ +DVWS G + A++L+ PIF GDS +DQL +I +++GTPT
Sbjct: 1223 CDLVVPGPRDPHGASKYSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPT 1044
Query: 341 REQIREMN--PNYTEFKFPQIKAHPWTKVFKSRTPPEAIALCSSLLEYT----PSSRLSP 394
+ E + P + FP W + S T + +L L+E T P+ R+S
Sbjct: 1043 EQTWPEFHKLPAFNGM-FPL-----WKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISC 882
Query: 395 LEACAHSFF 403
+ H++F
Sbjct: 881 KKMLQHAYF 855
>19301
Length = 712
Score = 64.3 bits (155), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 46/149 (30%), Positives = 79/149 (53%), Gaps = 1/149 (0%)
Frame = +2
Query: 120 TDIKVIGNGSFGVVYQARLAETRELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFF 179
TD++ +G+G+ G V+ +L E VA+KKV + K +++ +RKL+H NI+ +
Sbjct: 314 TDLEWLGSGAQGAVFLGKLCA--EEVAVKKV---RDIKETDIRNLRKLNHPNIISFK--- 469
Query: 180 YSSGEKKDELYLNLVLEYVP-ETVYRVARHFTKAKLTIPILYVKVYMYQLFRSLAYIHSQ 238
G +++EY P +Y V R + IP V + Q+ + Y+HS
Sbjct: 470 ---GVCTQAPCYCIIMEYCPYGQLYEVLRDGKE----IPPALVLDWSKQIASGMNYLHSH 628
Query: 239 GVCHRDIKPQNLLVDPDTAVLKLCDFGSA 267
+ HRD+K N+LV + V+K+ DFG++
Sbjct: 629 KIIHRDLKSPNVLVAKND-VVKISDFGTS 712
>26560
Length = 398
Score = 63.9 bits (154), Expect = 1e-10, Method: Composition-based stats.
Identities = 37/113 (32%), Positives = 63/113 (55%), Gaps = 4/113 (3%)
Frame = -1
Query: 221 VKVYMYQLFRSLAYIHSQGVCHRDIKPQNLLVDPDTAVLKLCDFGSAKQLVRGEPNVSYI 280
V+ Y ++ L ++HS+ V +RD+KP N+L+D + V ++ D G A + P+ S +
Sbjct: 350 VRFYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHV-RISDLGLACDFSKKRPHAS-V 177
Query: 281 CSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIF----PGDSGVDQL 329
+ Y APE++ Y SS D +S GC+L +LL G F G + +D++
Sbjct: 176 GTHGYMAPEVLMKGQSYDSSADWFSFGCMLYKLLKGHSPFRQHNQGQARIDRM 18
>12453
Length = 680
Score = 62.8 bits (151), Expect = 3e-10, Method: Compositional matrix adjust.
Identities = 31/102 (30%), Positives = 52/102 (50%), Gaps = 2/102 (1%)
Frame = +3
Query: 307 GCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREM--NPNYTEFKFPQIKAHPW 364
GC+ E+ G+P+FPG + D+L I K LGTPT + + + NP++ P +
Sbjct: 9 GCIFYEMACGRPLFPGSTVEDELHLIFKTLGTPTEDSLPSISRNPDFLALNLPHYQGEAL 188
Query: 365 TKVFKSRTPPEAIALCSSLLEYTPSSRLSPLEACAHSFFDEL 406
+ R + + L + L+Y R+S ++ HSFF+ L
Sbjct: 189 ITI-APRLDSDGLDLLAKFLKYNAKIRVSAADSLKHSFFNSL 311
>09007
Length = 1440
Score = 62.8 bits (151), Expect = 3e-10, Method: Compositional matrix adjust.
Identities = 60/222 (27%), Positives = 103/222 (46%), Gaps = 18/222 (8%)
Frame = -1
Query: 111 PERSQEVAYTDI----KVIGNGSFGVVYQA-RLAETRE--LVAIKKVLQDKRFKN----- 158
P R +++ D K +G G FG V QA AE+ E VA+K + +DK K+
Sbjct: 909 PARGKQLISKDCVALSKSLGQGHFGTVRQAIWTAESGEKVQVAVKCLSKDKIHKDGQEFL 730
Query: 159 RELQIMRKLDHCNIVRLRYFFYSSGEKKDELYLNLVLEYVPETVYRVARHFTKAKLTIPI 218
+E IM+ LDH NIVR+ +G + LV E P A++ +
Sbjct: 729 KETAIMQMLDHENIVRVYGVVMDNGAD-----IMLVTELAPMRSLLECVKEVSARVDFSV 565
Query: 219 LYVKVYMYQLFRSLAYIHSQGVCHRDIKPQNLLVDPDTAVLKLCD------FGSAKQLVR 272
+ + Q+ ++Y+ S+ + HRD+ +N+L+ + V K+ D G+ K+ +
Sbjct: 564 PRLCDFSQQVCDGMSYLESKRLVHRDLAARNILLFSKSKV-KISDVGVSGALGAGKEYYQ 388
Query: 273 GEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELL 314
+ + + + APE F ++S+ DVW+ G +L E
Sbjct: 387 SQQTIHLQNAVAWCAPE-SFRNLCFSSASDVWAFGVLLWEFF 265
>31885
Length = 529
Score = 62.0 bits (149), Expect = 5e-10, Method: Compositional matrix adjust.
Identities = 50/158 (31%), Positives = 79/158 (50%), Gaps = 4/158 (2%)
Frame = -2
Query: 161 LQIMRKLDHCNIVRLRYFFYSSGEKKDELYLNLVLEYVPETVYRVARHFTKAKLTIPILY 220
+ ++ +LDH +V L Y F + +++L++ + L + R+ + +++
Sbjct: 519 VDMLTRLDHPFLVNLWYAF----QDEEDLFMVVDLFLGGDL-----RYHMQQEVSFREDC 367
Query: 221 VKVYMYQLFRSLAYIHSQGVCHRDIKPQNLLVDPDTAVLKLCDFGSAKQLVRGEPNVSYI 280
VK Y+ QL L Y+ SQ + HRDIKP N+L+D + + DF A QL E S
Sbjct: 366 VKFYLCQLALVLDYLRSQKIVHRDIKPDNILLD-EQGHCHVTDFNIATQLEDDELATSTS 190
Query: 281 CSRYYRAPELIFGATD----YTSSIDVWSAGCVLAELL 314
+R Y APE+ A + Y +D WS G L ELL
Sbjct: 189 GTRPYMAPEVYGVAINERRGYGFPVDWWSLGVSLFELL 76
>01392
Length = 1806
Score = 61.2 bits (147), Expect = 8e-10, Method: Compositional matrix adjust.
Identities = 37/113 (32%), Positives = 60/113 (53%), Gaps = 12/113 (10%)
Frame = -1
Query: 227 QLFRSLAYIHSQGVCHRDIKPQNLLVD--PDTAVLKLCDFGSAKQL-VRGEPN-----VS 278
+ R+L ++HS+G+ HRD+KP+N+L + D +K+CDF A + G+ ++
Sbjct: 1767 HIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGISCDGDGTKTPELLT 1588
Query: 279 YICSRYYRAPELIFG----ATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVD 327
+ S Y APE++ + Y D+WS G +L +L G P F G G D
Sbjct: 1587 PVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILYIMLCGYPPFYGQCGED 1429
>12786
Length = 460
Score = 59.7 bits (143), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 36/124 (29%), Positives = 60/124 (48%), Gaps = 22/124 (17%)
Frame = -3
Query: 219 LYVKVYMYQLFRSLAYIHSQGVCHRDIKPQNLLVDPDTAVLKLCDFGSAKQLVRGEPNV- 277
+ +K Y ++ R++ +H++GV H D+KP N ++ LKL DFG A L + + +V
Sbjct: 410 MMIKFYWREMLRAVKALHNEGVIHSDLKPANFMLVAGN--LKLIDFGIANTLQQDKTSVL 237
Query: 278 --SYICSRYYRAPELIFGATDYTSS-------------------IDVWSAGCVLAELLLG 316
S + + Y +PE I A D ++ DVWS GC+L ++ G
Sbjct: 236 KDSRVGTPSYMSPEAIMAACDDSADDSMEEDGHRTKPKYKVGVRSDVWSLGCILYNMVYG 57
Query: 317 QPIF 320
+ F
Sbjct: 56 RTPF 45
>01718
Length = 959
Score = 59.3 bits (142), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 53/204 (25%), Positives = 90/204 (44%), Gaps = 7/204 (3%)
Frame = +3
Query: 125 IGNGSFGVVYQARLAETRELVAIKKVLQDKRFKN--RELQIMRKLDHCNIVRLRYFFYSS 182
IG G F V++ T +++A+K N RE+Q++ +L H NI+R
Sbjct: 171 IGAGFFSEVFKVTHRITGQVMALKMNTMTSNRHNMLREVQLLNRLQHANILRFMGVCVHE 350
Query: 183 GEKKDELYLNLVLEYVPETVYRVARHFTKAKLTIPILYVKVYMYQLFRSLAYIHSQGVCH 242
G+ L+ + EY+P + + K +P L R L Y+HS H
Sbjct: 351 GQ------LHALTEYIPSG--NLEQLLEKKDEELPWTQRIQLTLGLARGLDYLHSTRFIH 506
Query: 243 RDIKPQNLLV---DPDTAVLKLCDFGSAKQLVR--GEPNVSYICSRYYRAPELIFGATDY 297
RD+ +N+L+ D + DFG A ++ + + + S Y+ APE++ G Y
Sbjct: 507 RDLTSKNILIRREDNHGYHAVIADFGLATKIPDPLDKEKLPTVGSPYWMAPEVLNGHF-Y 683
Query: 298 TSSIDVWSAGCVLAELLLGQPIFP 321
D++S G ++ E+ P P
Sbjct: 684 NERADLFSVGIIMCEITARIPADP 755
>03294
Length = 1684
Score = 59.3 bits (142), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 37/109 (33%), Positives = 59/109 (54%), Gaps = 6/109 (5%)
Frame = -1
Query: 301 IDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMN--PNYTEFKFPQ 358
+DVWS G + A++L+ PIF GDS +DQL +I +++GTPT + E + P + FP
Sbjct: 1672 VDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKLPAFNGM-FPL 1496
Query: 359 IKAHPWTKVFKSRTPPEAIALCSSLLEYT----PSSRLSPLEACAHSFF 403
W + S T + +L L+E T P+ R+S + H++F
Sbjct: 1495 -----WKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYF 1364
>13212
Length = 1067
Score = 59.3 bits (142), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 55/183 (30%), Positives = 81/183 (44%), Gaps = 5/183 (2%)
Frame = -1
Query: 226 YQLFRSLAYIHSQGVCHRDIKPQNLLVDPDTAVLKLCDFG-SAKQLVRGEPNVSYICSRY 284
+++ +L ++H V HRDIK N+L+ D V KL DFG SAK + ++I + Y
Sbjct: 959 HEMCMALDFLHRHHVIHRDIKAGNVLLTIDGEV-KLADFGVSAKNTQTQQKRDTFIGTPY 783
Query: 285 YRAPELI----FGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPT 340
+ APE++ T Y D+WS G L E I P + + + +IK
Sbjct: 782 WMAPEVVLCETLKDTPYDFKADIWSLGVTLIEFAQ---IEPPNKEMHPMRVLIK------ 630
Query: 341 REQIREMNPNYTEFKFPQIKAHPWTKVFKSRTPPEAIALCSSLLEYTPSSRLSPLEACAH 400
I + +P E K WTK+FK + IA C L P+ R + E H
Sbjct: 629 ---IHKSDPPTLE------KPKKWTKLFK-----DFIAKC---LVKDPNLRPTAAELLEH 501
Query: 401 SFF 403
F
Sbjct: 500 PFM 492
>14420
Length = 528
Score = 58.9 bits (141), Expect = 4e-09, Method: Compositional matrix adjust.
Identities = 32/93 (34%), Positives = 53/93 (56%), Gaps = 1/93 (1%)
Frame = +2
Query: 227 QLFRSLAYIHSQGVCHRDIKPQNLLVDPDTAVLKLCDFGSAKQLVRGEPNVS-YICSRYY 285
+ ++L ++H V HRDIK N+L+ D +V KL DFG QL + S + + Y+
Sbjct: 221 ECLQALEFLHENQVIHRDIKSDNILLGMDGSV-KLTDFGFCAQLSPEQSKRSTMVGTPYW 397
Query: 286 RAPELIFGATDYTSSIDVWSAGCVLAELLLGQP 318
APE++ Y ++D+WS G + E++ G+P
Sbjct: 398 MAPEVV-TRKQYGPTVDIWSLGVMCIEMIEGEP 493
>27546
Length = 426
Score = 58.2 bits (139), Expect = 7e-09, Method: Composition-based stats.
Identities = 39/126 (30%), Positives = 61/126 (48%), Gaps = 11/126 (8%)
Frame = -1
Query: 154 KRFKNRELQIMRKLDHCNIVRLR---------YFFYSSGEKKDELYLNLVLEYVPETVYR 204
K+F REL+I+ +LDH NI+++ + F EK D L
Sbjct: 348 KKFFPRELEILTRLDHPNIIQIHSILQRGPKIFIFMRYAEKGDML--------------- 214
Query: 205 VARHFTKAKLTIPI--LYVKVYMYQLFRSLAYIHSQGVCHRDIKPQNLLVDPDTAVLKLC 262
+ K T PI KV+ +Q+ ++L Y+HS + HRD+K +N+L+ V K+
Sbjct: 213 -----SHIKKTGPIDEAQTKVWFFQMAKALQYLHSHDIAHRDLKCENILLSKRLNV-KIA 52
Query: 263 DFGSAK 268
DFG A+
Sbjct: 51 DFGFAR 34
>18401
Length = 463
Score = 57.4 bits (137), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 39/140 (27%), Positives = 60/140 (42%), Gaps = 16/140 (11%)
Frame = -3
Query: 280 ICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGT- 338
+ +R+YRAPE+I ++ DVWS GC++ EL G +F + L + ++LG+
Sbjct: 449 VSTRHYRAPEVIL-ELGWSHPCDVWSVGCIMFELYTGYTLFQTHDNKEHLAMMERILGSL 273
Query: 339 PTREQIREMNPNYTEF------------KFPQIKAHPWTKVFKSRTPPEA---IALCSSL 383
P R + Y ++ + P + K R + L L
Sbjct: 272 PYRMAKKTKKQKYFHHGRLDVPERSSMARYVRENTKPLLRYVKDRENKDHQQLFDLMKKL 93
Query: 384 LEYTPSSRLSPLEACAHSFF 403
L Y SSR S L+A H FF
Sbjct: 92 LAYEASSRYSLLQALQHPFF 33
>18287
Length = 678
Score = 57.0 bits (136), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 38/118 (32%), Positives = 54/118 (45%), Gaps = 7/118 (5%)
Frame = -3
Query: 297 YTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKF 356
Y SID+WS GC+ AELL + +F V QL II ++GTP E + E
Sbjct: 673 YDYSIDIWSVGCIFAELLSRRILFQAQGPVQQLDMIINLVGTPRPEDMERA----CEGAR 506
Query: 357 PQIKAHPWTKV-------FKSRTPPEAIALCSSLLEYTPSSRLSPLEACAHSFFDELR 407
I P+ + EA+ L + +L P +R+S EA +H + DE R
Sbjct: 505 NHILNQPFRRQNLLTLYNLSPHATHEAVRLLTRMLILNPKNRISAEEALSHPYLDEGR 332
>27405
Length = 532
Score = 56.2 bits (134), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 55/190 (28%), Positives = 91/190 (47%), Gaps = 14/190 (7%)
Frame = -3
Query: 129 SFGVVYQARLAETRELVAIKKVLQDKRFKNR-------ELQIMRKLDHCN-----IVRLR 176
FG VY R A+T ++ A+K L KR K + +IM L IV +
Sbjct: 530 GFGEVYGCRKADTGKMYAMK-CLDKKRIKMKGGETLALNERIMLSLVSTGEGSPFIVCMT 354
Query: 177 YFFYSSGEKKDELYLNLVLEYVPETVYRVARH--FTKAKLTIPILYVKVYMYQLFRSLAY 234
Y F + ++L L L + Y +++H FT+ + V+ Y ++ L +
Sbjct: 353 YAF----QTPEKLCFILDLMNGGDLHYHLSQHGVFTEKE-------VRFYAAEVMLGLEH 207
Query: 235 IHSQGVCHRDIKPQNLLVDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGA 294
+HS+ V +RD+KP N+L+D + V ++ D G A + +P+ S + + Y APE++
Sbjct: 206 MHSRFVVYRDLKPANILLDENGHV-RISDLGLACDFSKKKPHAS-VGTHGYMAPEVLMKG 33
Query: 295 TDYTSSIDVW 304
Y SS D W
Sbjct: 32 QAYDSSAD-W 6
>17975
Length = 449
Score = 55.8 bits (133), Expect = 4e-08, Method: Composition-based stats.
Identities = 45/151 (29%), Positives = 76/151 (50%), Gaps = 6/151 (3%)
Frame = +3
Query: 130 FGVVYQARLAETRELVAIK---KVLQDKRFKN---RELQIMRKLDHCNIVRLRYFFYSSG 183
F VV AR T E VA+K K D+ ++ +E++ M+ + H N+VRL Y
Sbjct: 6 FAVVKLARHVFTGEKVAVKVIDKTKLDEVSRSHLFQEVRCMKLVQHPNVVRL----YEVI 173
Query: 184 EKKDELYLNLVLEYVPETVYRVARHFTKAKLTIPILYVKVYMYQLFRSLAYIHSQGVCHR 243
+ + +LYL L L + + RH + + K Y Q+ +++Y H V HR
Sbjct: 174 DTQTKLYLILELGDGGDMYDYIMRHSGGLEEKL----AKRYFRQIVEAISYCHKLHVVHR 341
Query: 244 DIKPQNLLVDPDTAVLKLCDFGSAKQLVRGE 274
D+KP+N++ ++KL DFG + L++ +
Sbjct: 342 DLKPENVVFFEKPGLVKLTDFGFSTCLLQAK 434
>07940
Length = 1336
Score = 55.8 bits (133), Expect = 4e-08, Method: Compositional matrix adjust.
Identities = 37/102 (36%), Positives = 54/102 (52%), Gaps = 4/102 (3%)
Frame = -3
Query: 224 YMYQLFRSLAYIHSQGVCHRDIKPQNLLVDPDTAVLKLCDFGSAKQLVRGEPNVSYICSR 283
Y YQ+ R + Y+ S+ HRD+ +N+LV + VLK+ DFG + L + + R
Sbjct: 332 YAYQVARGMEYLASKQCIHRDLAARNVLV-AEEYVLKIADFGLTRNLQQFDYYRKTTDGR 156
Query: 284 Y---YRAPELIFGATDYTSSIDVWSAGCVLAELL-LGQPIFP 321
+ APE +F YTS DVWS G +L E+ LG +P
Sbjct: 155 LPVKWMAPEALFDRK-YTSKSDVWSYGVLLWEIFTLGGNPYP 33
>26711
Length = 405
Score = 55.1 bits (131), Expect = 6e-08, Method: Composition-based stats.
Identities = 34/104 (32%), Positives = 54/104 (51%), Gaps = 1/104 (0%)
Frame = -2
Query: 227 QLFRSLAYIHSQGVCHRDIKPQNLLVDPDTA-VLKLCDFGSAKQLVRGEPNVSYICSRYY 285
Q+ L ++H+QGV H D+KP NLL+ D ++L DFG A++L + + +
Sbjct: 392 QVLDILQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARKLYPPQETFLNHGTPGF 213
Query: 286 RAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQL 329
+PE + +++ DVW G + LL GQ F DS + L
Sbjct: 212 TSPEAL-DVKPISTASDVWGVGVLAYILLSGQSPFQADSATESL 84
>31489
Length = 329
Score = 54.7 bits (130), Expect = 8e-08, Method: Composition-based stats.
Identities = 27/91 (29%), Positives = 50/91 (54%)
Frame = +3
Query: 161 LQIMRKLDHCNIVRLRYFFYSSGEKKDELYLNLVLEYVPETVYRVARHFTKAKLTIPILY 220
++I++ H NI+ +R D +++V + + ++R+ ++ LT +
Sbjct: 3 IKILKHFKHDNIISIREILKPKDSYHDFKDIHVVFDLMESDLHRII--YSDQPLTEE--H 170
Query: 221 VKVYMYQLFRSLAYIHSQGVCHRDIKPQNLL 251
++ ++YQ+ R L YIHS V HRD+KP NLL
Sbjct: 171 IRYFLYQILRGLKYIHSANVVHRDLKPSNLL 263
>21433
Length = 590
Score = 52.0 bits (123), Expect = 5e-07, Method: Compositional matrix adjust.
Identities = 35/95 (36%), Positives = 52/95 (54%)
Frame = +2
Query: 224 YMYQLFRSLAYIHSQGVCHRDIKPQNLLVDPDTAVLKLCDFGSAKQLVRGEPNVSYICSR 283
Y+YQL +L Y H + V HRDIKP+NLL+ LK+ DFG + + +
Sbjct: 182 YIYQLSSALEYCHYRKVIHRDIKPENLLLG-LKGDLKIADFGWSVHAPSSR-RTTMCGTL 355
Query: 284 YYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQP 318
Y PE++ G T + ++D+WS G + E L+G P
Sbjct: 356 DYLPPEMVEGKT-HDENVDLWSLGVLCYEFLVGTP 457
>14477
Length = 493
Score = 52.0 bits (123), Expect = 5e-07, Method: Compositional matrix adjust.
Identities = 51/184 (27%), Positives = 89/184 (48%), Gaps = 9/184 (4%)
Frame = -1
Query: 115 QEVAYTDIKVIGNGSFGVVYQA--RLAETRELVAIKKVLQDKRFK-------NRELQIMR 165
+++ ++K +G G+FG V + RL + RE+ KVL++ +E ++M+
Sbjct: 493 EQIQMDELK-LGAGNFGSVMKGVCRL-DDREIPVAIKVLKNADLDPSVQSELIKEAEVMK 320
Query: 166 KLDHCNIVRLRYFFYSSGEKKDELYLNLVLEYVPETVYRVARHFTKAKLTIPILYVKVYM 225
K+DH +IVRL GE + LVLE + + + K K +P+ + M
Sbjct: 319 KMDHMHIVRL--IGLCEGET-----MMLVLELA--KLGPLNKFLPKNK-HLPLWNILELM 170
Query: 226 YQLFRSLAYIHSQGVCHRDIKPQNLLVDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYY 285
+Q+ + + Y+ + HRD+ +N+L+ D K+ DFG +K L R + YY
Sbjct: 169 WQVSQGMEYLEANKFVHRDLAARNILL-CDEHFAKISDFGMSKTLSRE--------NNYY 17
Query: 286 RAPE 289
A E
Sbjct: 16 MAQE 5
>19094
Length = 898
Score = 51.6 bits (122), Expect = 6e-07, Method: Compositional matrix adjust.
Identities = 34/99 (34%), Positives = 50/99 (50%), Gaps = 2/99 (2%)
Frame = +1
Query: 221 VKVYMYQLFRSLAYIHSQGVCHRDIKPQNLLVDPDTAVLKLCDFGSAKQL--VRGEPNVS 278
+ +Y + L Y+HS+ HRDIK N+L++ + KL DFG A QL + N +
Sbjct: 64 IATILYYTLKGL*YLHSRRKIHRDIKAGNILLNNEGHA-KLADFGVAGQLTDTMAKRN-T 237
Query: 279 YICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQ 317
I + Y+ APE+I Y D+WS G E+ G
Sbjct: 238 VIGTPYWMAPEVIQ-EIGYDCVADIWSLGITALEMAEGN 351
>19761
Length = 473
Score = 51.6 bits (122), Expect = 6e-07, Method: Compositional matrix adjust.
Identities = 37/128 (28%), Positives = 63/128 (49%), Gaps = 6/128 (4%)
Frame = -3
Query: 216 IPILYVKVYMYQLFRSLAYIHSQG--VCHRDIKPQNLLVDPDTAVLKLCDFGSAKQLVR- 272
+P + ++ Q +L Y+H+ + HRD+KPQN+ V V +L D G A++L
Sbjct: 432 LPERLIVCWLMQTASALNYMHTHTPVILHRDLKPQNIYVTEKGDV-RLGDLGLARKLTGP 256
Query: 273 GEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQ---L 329
+ S + + Y +PE I Y S D+WS GCV ++ G G D+ +
Sbjct: 255 ADFATSQVGTIMYLSPE-ILSQQPYNSKSDIWSLGCVFYDI-------TGKKGSDEMGVM 100
Query: 330 VEIIKVLG 337
+++V+G
Sbjct: 99 FLLVQVMG 76
>21808
Length = 1011
Score = 51.2 bits (121), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 47/177 (26%), Positives = 88/177 (49%), Gaps = 4/177 (2%)
Frame = +1
Query: 160 ELQIMRKLDHCNIVRLRYFFYSSGEKKDELYLNLVLEYVPETVYRVARHFTKAKLTIPIL 219
E QIM+KL H +++L Y+ + D +++ + E + L +P L
Sbjct: 82 EAQIMKKLRHPKLIQL----YAVCTQDDPIFI--ITELMKNGSLLEFLQGKGRVLKLPAL 243
Query: 220 YVKVYMYQLFRSLAYIHSQGVCHRDIKPQNLLVDPDTAVLKLCDFGSAKQLVRGEPNVSY 279
+ + Q+ +AY+ SQ HRD+ +N+LV D +K+ DFG A+ +++ + +
Sbjct: 244 -IDIGA-QIACGMAYLESQNYIHRDLAARNILVS-DNNTVKIADFGLAR-VIKEDEYEAR 411
Query: 280 ICSRY---YRAPELIFGATDYTSSIDVWSAGCVLAE-LLLGQPIFPGDSGVDQLVEI 332
+ +R+ + APE +T DVWS G +L E + G+ +PG + + L ++
Sbjct: 412 VGARFPIKWTAPEAA-NYNRFTIKSDVWSFGILLTETVTYGRVPYPGMTNAEVLHQV 579
>14116
Length = 1017
Score = 50.1 bits (118), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 55/213 (25%), Positives = 88/213 (41%), Gaps = 23/213 (10%)
Frame = -1
Query: 125 IGNGSFGVVYQARLA---ETRELVAIKKVLQDKRFKNRELQ-------IMRKLDHCNIVR 174
IG G+FG V + L + +++ K L + + ELQ IM+ H N++
Sbjct: 612 IGKGNFGCVKRGFLTLPEQKGDILVAVKTLHNNNPREIELQSFLQEALIMKDFHHSNVLT 433
Query: 175 LRYFFYSSGEKKDELYLNLVLEYVPETVYRVARH-----FTKAKLTIP-ILYVKVYMYQL 228
L + + L L+ +P V +H + + P I + +Y +
Sbjct: 432 L-------------IGICLNLDDMPLVVLPFMKHGDLLTYIRDDQHQPTIKDLIMYGVDI 292
Query: 229 FRSLAYIHSQGVCHRDIKPQNLLVDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAP 288
R + Y+ HRD+ +N ++D D V K+ DFG A+ + E Y S +A
Sbjct: 291 ARGMDYLAGLKFVHRDLAARNCMLDEDFHV-KVADFGLARDIYEKE----YYSSENKKAK 127
Query: 289 ELI-------FGATDYTSSIDVWSAGCVLAELL 314
+ +Y S DVWS G VL ELL
Sbjct: 126 LPVKWMALESLEKGNYDSKTDVWSYGVVLWELL 28
>04852
Length = 1462
Score = 50.1 bits (118), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 33/97 (34%), Positives = 51/97 (52%), Gaps = 2/97 (2%)
Frame = +1
Query: 224 YMYQLFRSLAYIHSQGVCHRDIKPQNLLVDPDTAVLKLCDFGSAKQLVRGEPNVSYICSR 283
Y +Q+ R + ++ S+ HRD+ +N+LV + VLK+ DFG ++ +
Sbjct: 340 YAFQIARGMEFLASRKCIHRDLAARNVLV-TEEHVLKIADFGLSRTGDYYKKRSGGRLPV 516
Query: 284 YYRAPELIFGATDYTSSIDVWSAGCVLAEL--LLGQP 318
+ APE +F YT+ DVWS G VL E+ L G P
Sbjct: 517 KWMAPEALFDMR-YTTKSDVWSFGVVLWEIFSLGGMP 624
>21079
Length = 878
Score = 48.9 bits (115), Expect = 5e-06, Method: Compositional matrix adjust.
Identities = 28/95 (29%), Positives = 54/95 (56%), Gaps = 2/95 (2%)
Frame = +1
Query: 224 YMYQLFRSLAYIHSQGVCHRDIKPQNLL-VDPDTAVLKLCDFGSAKQLVRGEPNVSYICS 282
++ Q+ + Y+H+Q + H D+KP+N+L V ++ +K+ DFG A+ G+ +
Sbjct: 142 FVRQICSGVGYMHTQSILHLDLKPENVLCVSDNSNQIKIIDFGLARFYKPGDSLQVLFGT 321
Query: 283 RYYRAPELI-FGATDYTSSIDVWSAGCVLAELLLG 316
+ APE++ + ++T+ D+WS G + LL G
Sbjct: 322 PEFIAPEVVNYDEINFTT--DMWSIGVICYILLSG 420
>11185
Length = 473
Score = 47.8 bits (112), Expect = 9e-06, Method: Composition-based stats.
Identities = 35/122 (28%), Positives = 53/122 (43%), Gaps = 26/122 (21%)
Frame = +1
Query: 221 VKVYMYQLFRSLAYIHSQGVCHRDIKPQNLLVDPDTAVLKLCDFG--------------- 265
++ + L L YIHS G+ D++P +L+D + VLK DFG
Sbjct: 7 IRDFGIHLVTGLHYIHSLGILFHDLRPSKVLLD-TSGVLKFADFGLSKVEGENLEELFFK 183
Query: 266 -----------SAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELL 314
SA+++++ P S Y APE+ GA S D+W+ GCV E+
Sbjct: 184 FAEAGDQWNIQSAEEMMKQVPTSG---SPTYMAPEVFQGAEPSIMS-DLWALGCVFYEMF 351
Query: 315 LG 316
G
Sbjct: 352 SG 357
>16708
Length = 1397
Score = 46.2 bits (108), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 43/153 (28%), Positives = 71/153 (46%), Gaps = 6/153 (3%)
Frame = -1
Query: 122 IKVIGNGSFGVVYQARLAETRELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYS 181
++V+G G FG VY+ARL T E A+K + + E++ + +++ L F +
Sbjct: 1388 LQVLGKGVFGKVYEARLLSTHEKAALKTSILCHHSLD-EVEALGRIE--GGFYLAQMFGA 1218
Query: 182 SGEKKDELYLNLVLE-YVPETVYRVARHFTKAKLTIPILYVKVYMY-----QLFRSLAYI 235
+N++L Y + V H+ ++ PI + M Q +L +I
Sbjct: 1217 WVTCLPFPKMNILLHFYEMGPLCNVYAHYKNKEM--PIRWSNPAMVCCIAGQXVCALEHI 1044
Query: 236 HSQGVCHRDIKPQNLLVDPDTAVLKLCDFGSAK 268
H GV H D+K N+LVD KL D+G A+
Sbjct: 1043 HELGVVHMDVKADNVLVDAH-GNCKLTDYGIAQ 948
>00715
Length = 1788
Score = 45.4 bits (106), Expect = 5e-05, Method: Compositional matrix adjust.
Identities = 36/119 (30%), Positives = 50/119 (42%), Gaps = 23/119 (19%)
Frame = +1
Query: 227 QLFRSLAYIHSQGVCHRDIKPQNLLVDPDTAVLKLCDFGSAKQL---------------- 270
Q+ R L Y+HS + H D+KP N L+ D L++ DFG QL
Sbjct: 262 QMARGLHYLHSINIVHLDLKPANCLLTRDLK-LRIADFGCCHQLTPTGLDMGEREGGMAG 438
Query: 271 -------VRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPG 322
V+G + YRAPEL+ G S DV+S G L ++ Q + G
Sbjct: 439 NELELTPVQGAWKNELAGTLAYRAPELLKGLQPSVRS-DVYSLGITLWQMCTRQGPYEG 612
>28157
Length = 400
Score = 45.4 bits (106), Expect = 5e-05, Method: Composition-based stats.
Identities = 37/128 (28%), Positives = 63/128 (49%), Gaps = 5/128 (3%)
Frame = +3
Query: 145 VAIKKVL--QDKRFKNRELQIMRKLDHCNIVRLRYFFYSSGEKKDELYLNLVLEYVPETV 202
VA+K++ Q+K+ +EL+ + ++ H NIV L G +D + LV+EY
Sbjct: 9 VAVKRIESEQEKKSFMQELKQLSRVSHPNIVCLY------GACRDHP-VCLVMEYAEGGS 167
Query: 203 YRVARHFTKAKLTIPILYVKVYMYQLFRSLAYIHS---QGVCHRDIKPQNLLVDPDTAVL 259
H + + + ++ Q + Y+H + + HRD+KP NLL+ L
Sbjct: 168 LYNVLHGSGPQPQYTAAHAMNWLLQCALGVEYLHGMKPKALIHRDLKPPNLLLIQCGTKL 347
Query: 260 KLCDFGSA 267
K+CDFG+A
Sbjct: 348 KICDFGTA 371
>11404
Length = 563
Score = 43.9 bits (102), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 42/141 (29%), Positives = 71/141 (50%), Gaps = 12/141 (8%)
Frame = +1
Query: 124 VIGNGSFGVVYQARLAETRELVAIKKVLQDKRFKNRE------LQIMRKLDHCN---IVR 174
+IG GSFG V +A E VAIK + K F N+ L++M + D N IVR
Sbjct: 160 LIGKGSFGQVVKAYDHTDNEQVAIKIIKNKKPFLNQAQIEVKLLEMMNRHDTDNKYYIVR 339
Query: 175 L-RYFFYSSGEKKDELYLNLVLEYVPETVYRVARHFTKAKLTIPILYVKVYMYQLFRSLA 233
L R+F + S +L LV E + +Y + R+ +++ + + + QL +L
Sbjct: 340 LKRHFMFRS-------HLCLVFELLSYNLYDLLRNTNFRGVSLNL--TRKFAQQLCTALL 492
Query: 234 YIHS--QGVCHRDIKPQNLLV 252
++ + + H D+KP+N+L+
Sbjct: 493 FLATPEMSIIHCDLKPENILL 555
>07291
Length = 833
Score = 39.7 bits (91), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 30/95 (31%), Positives = 43/95 (45%), Gaps = 7/95 (7%)
Frame = +1
Query: 227 QLFRSLAYIHSQGVCHRDIKPQNLLVDPDTAVLKLCDFGSAKQLVRGEPNVSYICSR--- 283
Q+ +AY+ V HR++ +N +V D L+L D+G L P Y
Sbjct: 73 QIADGMAYLQEVKVVHRNLAARNCIVTED-GRLQLSDYGVTGSLF---PQSYYTADDSPA 240
Query: 284 ----YYRAPELIFGATDYTSSIDVWSAGCVLAELL 314
+ APE I ++S DVW+ G VL ELL
Sbjct: 241 RDLVKWMAPETI-DNFHFSSKSDVWAFGVVLWELL 342
>00638
Length = 1595
Score = 39.7 bits (91), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 14/33 (42%), Positives = 24/33 (72%)
Frame = +2
Query: 221 VKVYMYQLFRSLAYIHSQGVCHRDIKPQNLLVD 253
++ Y+Y+L ++L + HS G+ HRD+KP LV+
Sbjct: 422 IRFYLYELMKALDFCHSMGIMHRDVKPSPPLVN 520
>16003
Length = 926
Score = 39.7 bits (91), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 21/60 (35%), Positives = 34/60 (56%), Gaps = 2/60 (3%)
Frame = -1
Query: 313 LLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMN--PNYTEFKFPQIKAHPWTKVFKS 370
LL+ P PGD+ +DQL +I +LGTPT + + P+Y +FK + P ++F +
Sbjct: 926 LLIRLPFLPGDTDLDQLGKIFNMLGTPTETEWPAVTSLPDYIQFK--HCQKQPLKEIFTA 753
>26009
Length = 886
Score = 38.9 bits (89), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 17/36 (47%), Positives = 25/36 (69%), Gaps = 1/36 (2%)
Frame = +3
Query: 221 VKVYMYQLFRSLAYIHSQGVCHRDIKPQNLLV-DPD 255
K M QL +L ++HS+ + HRDIKP+N+L+ PD
Sbjct: 717 AKSVMKQLVSALDFMHSKQLVHRDIKPENVLILTPD 824
>01106
Length = 878
Score = 37.4 bits (85), Expect = 0.013, Method: Compositional matrix adjust.
Identities = 17/46 (36%), Positives = 30/46 (65%), Gaps = 1/46 (2%)
Frame = +3
Query: 216 IPILYVKVYMYQLFRSLAYIHSQG-VCHRDIKPQNLLVDPDTAVLK 260
IPI VK+ + Q+ L+Y+H++ + H DIKP+N+L+ D ++
Sbjct: 636 IPIHNVKLIIRQVLEGLSYMHAKCRIIHTDIKPENILICVDETYIR 773
>21800
Length = 855
Score = 36.6 bits (83), Expect = 0.022, Method: Compositional matrix adjust.
Identities = 16/41 (39%), Positives = 27/41 (65%), Gaps = 1/41 (2%)
Frame = +2
Query: 216 IPILYVKVYMYQLFRSLAYIHSQ-GVCHRDIKPQNLLVDPD 255
IP+ VK+ + Q+ L Y+H++ + H DIKP+N+L+ D
Sbjct: 623 IPVHNVKLIIRQVLEGLNYLHAKCNIIHTDIKPENILICVD 745
>25019
Length = 730
Score = 36.6 bits (83), Expect = 0.023, Method: Compositional matrix adjust.
Identities = 23/61 (37%), Positives = 31/61 (50%), Gaps = 1/61 (1%)
Frame = +3
Query: 248 QNLLVDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRY-YRAPELIFGATDYTSSIDVWSA 306
+N+L+D D V KL DFG K+ + G C Y APE I T + ++D WS
Sbjct: 261 ENVLLDKDGHV-KLTDFGLCKEAITGTRVTHTFCGTIEYMAPE-ILTRTGHGKAVDWWSL 434
Query: 307 G 307
G
Sbjct: 435 G 437
>18996
Length = 491
Score = 35.4 bits (80), Expect = 0.048, Method: Compositional matrix adjust.
Identities = 26/77 (33%), Positives = 38/77 (49%), Gaps = 4/77 (5%)
Frame = +2
Query: 242 HRDIKPQNLLVDPDTAVLKLCDFGSAKQLVRGEPNVSYICSR----YYRAPELIFGATDY 297
HRD+ +N+LV D + +K+ DFG A Q + I R + +PE I +
Sbjct: 5 HRDLAARNILV--DRSCVKISDFGLA-QFANADGYYYGISQRDIPIKWYSPEAI-ETCKF 172
Query: 298 TSSIDVWSAGCVLAELL 314
+S DVWS G L E+
Sbjct: 173 SSYSDVWSYGVTLFEMF 223
>36481
Length = 806
Score = 35.4 bits (80), Expect = 0.050, Method: Compositional matrix adjust.
Identities = 32/137 (23%), Positives = 59/137 (43%), Gaps = 11/137 (8%)
Frame = +2
Query: 126 GNGSFGVVYQARLAETRELVAIKKVLQDKRFKNR---ELQIMRKL-------DHCNIVRL 175
G G+FG V Q + + +A+K + +++ E+ ++ KL H + L
Sbjct: 389 GEGTFGKVVQCKDLLKGDDIALKIIKNVDKYREAAKLEINVLEKLREKDPHAKHMCVQML 568
Query: 176 RYFFYSSGEKKDELYLNL-VLEYVPETVYRVARHFTKAKLTIPILYVKVYMYQLFRSLAY 234
+F Y L L V +++ + Y PI V+ YQL ++ +
Sbjct: 569 DWFDYHGHVCISFHMLGLSVFDFLKDNSYG----------AYPIEQVRHISYQLCYAVNF 718
Query: 235 IHSQGVCHRDIKPQNLL 251
+H + H D+KP+N+L
Sbjct: 719 LHENQLTHTDLKPENIL 769
>13078
Length = 773
Score = 35.0 bits (79), Expect = 0.064, Method: Compositional matrix adjust.
Identities = 13/42 (30%), Positives = 23/42 (54%)
Frame = -1
Query: 297 YTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGT 338
++ DVWS GC++ EL G +F + L + ++LG+
Sbjct: 746 WSQPCDVWSIGCIMFELYTGYTLFQTHDNKEHLAMMERILGS 621
>02638
Length = 1490
Score = 35.0 bits (79), Expect = 0.068, Method: Compositional matrix adjust.
Identities = 17/51 (33%), Positives = 28/51 (54%)
Frame = +1
Query: 285 YRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKV 335
+ APE++ G + Y + DVWS GCV+ E+ +P + + L I K+
Sbjct: 34 FMAPEVLRGES-YGRACDVWSVGCVMIEMCTCRPPWNSHDISNHLALIFKI 183
>37602
Length = 804
Score = 33.9 bits (76), Expect = 0.13, Method: Compositional matrix adjust.
Identities = 16/36 (44%), Positives = 22/36 (61%)
Frame = -1
Query: 229 FRSLAYIHSQGVCHRDIKPQNLLVDPDTAVLKLCDF 264
+ L Y+H +G HRDIK N+L+ + V KL DF
Sbjct: 189 LKGLHYLHRRGKMHRDIKGANILLTEEGDV-KLADF 85
>00486
Length = 797
Score = 33.9 bits (76), Expect = 0.16, Method: Compositional matrix adjust.
Identities = 16/50 (32%), Positives = 28/50 (56%)
Frame = -2
Query: 285 YRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIK 334
Y APE I T + ++D WS G ++ ++L G P F ++ + +I+K
Sbjct: 760 YMAPE-ILTRTGHGKAVDWWSLGALMYDMLTGSPPFTAENRKKTIDKILK 614
>20152
Length = 445
Score = 33.1 bits (74), Expect = 0.24, Method: Composition-based stats.
Identities = 22/86 (25%), Positives = 38/86 (44%), Gaps = 9/86 (10%)
Frame = +1
Query: 288 PELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKV-------LGTPT 340
PE++ G + ++DVWS G +L L++G+ F + + L I+ +
Sbjct: 1 PEILLGDSYDAPAVDVWSLGVILYMLVVGEAPFQEANDSETLTMIMDCRYQIPPHISHKC 180
Query: 341 REQIREM--NPNYTEFKFPQIKAHPW 364
++ I +M P I AHPW
Sbjct: 181 QDLIEKMLQREPVDRASLPHILAHPW 258
>29360
Length = 363
Score = 33.1 bits (74), Expect = 0.28, Method: Composition-based stats.
Identities = 29/120 (24%), Positives = 56/120 (46%), Gaps = 8/120 (6%)
Frame = +3
Query: 141 TRELVAIKKVLQDKRFKNR---ELQIMRKL-----DHCNIVRLRYFFYSSGEKKDELYLN 192
T E+VAIK + + + E+ I+++L D N VR F + + +
Sbjct: 24 TSEIVAIKILKNHPSYARQGQIEVSILQRLSQESADDYNFVRAFECF------QHKNHTC 185
Query: 193 LVLEYVPETVYRVARHFTKAKLTIPILYVKVYMYQLFRSLAYIHSQGVCHRDIKPQNLLV 252
LV E + + +Y + L P+ Y++ Q+ +L + G+ H D+KP+N+++
Sbjct: 186 LVFEMLEQNLYDFLKQNKFQPL--PLKYIRPITQQVLTALRKLKQLGLIHADLKPENIML 359
>38560
Length = 479
Score = 32.7 bits (73), Expect = 0.29, Method: Composition-based stats.
Identities = 16/32 (50%), Positives = 18/32 (56%)
Frame = -3
Query: 285 YRAPELIFGATDYTSSIDVWSAGCVLAELLLG 316
Y APELI G S D+WS G +L LL G
Sbjct: 387 YAAPELISGLEYLGSEADIWSMGVLLYALLCG 292
>18481
Length = 437
Score = 32.7 bits (73), Expect = 0.30, Method: Composition-based stats.
Identities = 17/45 (37%), Positives = 24/45 (53%), Gaps = 2/45 (4%)
Frame = -1
Query: 227 QLFRSLAYIHSQGVCHRDIKPQNLLVDPDTAV--LKLCDFGSAKQ 269
QL L +IH + HRD+KP N L+ L + DFG +K+
Sbjct: 173 QLLSRLEFIHQKCFIHRDLKPDNFLMGLGRHCHRLYIIDFGLSKR 39
>24241
Length = 413
Score = 30.8 bits (68), Expect = 1.4, Method: Composition-based stats.
Identities = 18/55 (32%), Positives = 29/55 (52%), Gaps = 10/55 (18%)
Frame = -2
Query: 125 IGNGSFGVVYQARLAETRELVAIKKVLQDKRFKN----------RELQIMRKLDH 169
IG G++GVVY+ R T +A+KK+ R + RE+ ++R+L H
Sbjct: 319 IGEGTYGVVYKCRHRATGRKLAMKKI----RLRGSEDGVPSSAIREIAMLRELRH 167
>17806
Length = 433
Score = 30.8 bits (68), Expect = 1.4, Method: Composition-based stats.
Identities = 24/78 (30%), Positives = 37/78 (47%), Gaps = 10/78 (12%)
Frame = +1
Query: 108 GQGPERSQEVAYTDIKVIGNGSFGVVYQARLAETRELVA----IKKVLQDKRFKNRELQI 163
G P ++ Y +K +G G FG V ++ V+ + K+L+D K+ +L
Sbjct: 28 GHHPFPRSQIVY--LKELGTGWFGKVIESDAERITTGVSRSKVVVKMLKDDATKDEQLLF 201
Query: 164 M------RKLDHCNIVRL 175
R+LDH NIVRL
Sbjct: 202 FEEVAPFRELDHPNIVRL 255
>35032
Length = 465
Score = 29.6 bits (65), Expect = 2.6, Method: Compositional matrix adjust.
Identities = 16/32 (50%), Positives = 18/32 (56%), Gaps = 1/32 (3%)
Frame = +3
Query: 379 LCSSLLEYTPSSRLSPLEACAHSF-FDELRCL 409
L LL Y PS RL+P A AH F + L CL
Sbjct: 150 LVKRLLNYDPSKRLTPXXALAHPFLYX*LACL 245
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000273130 | hsapiens_gene_ensembl | Cytoplasmic
dynein 1 light intermediate chain 1 (Dynein light intermediate chain
1, cytosolic) (Dynein light chain A) (DLC-A).
[Source:Uniprot/SWISSPROT;Acc:Q9Y6G9]
(523 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
06254 251 2e-69
35964 33 0.41
05468 31 1.4
26083 30 3.3
07465 28 9.1
>06254
Length = 2204
Score = 251 bits (642), Expect(2) = 2e-69, Method: Compositional matrix adjust.
Identities = 119/215 (55%), Positives = 162/215 (75%), Gaps = 7/215 (3%)
Frame = +2
Query: 179 PPEEMKQMEQKLIRDFQEYVEP--GEDFPASPQRRNT----ASQEDKDDSVVLPLGADTL 232
P ++M+ EQ L+R FQ+Y P G+ +P R + + DD VVLPLG + L
Sbjct: 215 PQKKMRDYEQSLVRFFQDYTAPEEGQSSSQAPPRGDANPLHPALMTDDDKVVLPLGDNVL 394
Query: 233 THNLGIPVLVVCTKCDAISVLEKEHDYRDEHFDFIQSHIRKFCLQYGAALIYTSVKENKN 292
THNLGIPV+VV TKCDAIS LEK+HD+R+EHFDFIQ ++RKFCL+YGA L YTSVK+ +N
Sbjct: 395 THNLGIPVVVVLTKCDAISSLEKDHDFREEHFDFIQQYVRKFCLKYGAGLFYTSVKDERN 574
Query: 293 IDLVYKYIVQKLYGFPYKIPAVVVEKDAVFIPAGWDNDKKIGILHENFQTLKAEDNFEDI 352
+L+Y+Y+V ++YGFP+ PA VV++D+VF+P GWDN+KKI IL+EN ++K ED ED+
Sbjct: 575 CELLYRYLVHRIYGFPFTTPAYVVDRDSVFVPCGWDNEKKISILYENMSSVKPEDGLEDV 754
Query: 353 ITKPPVRKFVH-EKEIMAEDDQVFLMKLQSLLAKQ 386
I +P +RK V + E+ AED+QV+LMKLQ++LAKQ
Sbjct: 755 IVRPVLRKPVQRDAEVFAEDEQVYLMKLQAVLAKQ 859
Score = 29.6 bits (65), Expect(2) = 2e-69, Method: Compositional matrix adjust.
Identities = 16/29 (55%), Positives = 19/29 (65%), Gaps = 4/29 (13%)
Frame = +1
Query: 427 SKKIDPNMKAGAT----SEGVLANFFNSL 451
S K + KAG T +EG+LANFFNSL
Sbjct: 964 SPKCGKDPKAGGTPGQATEGMLANFFNSL 1050
Score = 60.5 bits (145), Expect(2) = 3e-15, Method: Compositional matrix adjust.
Identities = 24/51 (47%), Positives = 40/51 (78%)
Frame = +1
Query: 140 SLKDTLVMLVVDMSKPWTALDSLQKWASVVREHVDKLKIPPEEMKQMEQKL 190
+ +D++VMLV M++PW+ DSL KW +V+ +H+DKL+IPPE+ +++ KL
Sbjct: 97 TFEDSMVMLVASMAQPWSIADSLTKWITVLSQHIDKLRIPPEKNERLXTKL 249
Score = 39.3 bits (90), Expect(2) = 3e-15, Method: Compositional matrix adjust.
Identities = 15/26 (57%), Positives = 20/26 (76%)
Frame = +3
Query: 111 RDDQTRCNVWILDGDLYHKGLLKFSL 136
RD+Q R NVW+LDGD H L+K++L
Sbjct: 9 RDEQARLNVWVLDGDQSHTALMKYAL 86
>35964
Length = 863
Score = 32.7 bits (73), Expect = 0.41, Method: Compositional matrix adjust.
Identities = 28/111 (25%), Positives = 49/111 (44%)
Frame = +1
Query: 50 SCILSEVSTRSRSKLPAGKNVLLLGEDGAGKTSLIRKIQGIEEYKKGRGLEYLYLNVHDE 109
+C+ + +S R S P V ++G +T L + + R L + H +
Sbjct: 337 TCVPTHLSYRQES--PLCMYVCMIGVHSHMRTHLHN*LVXLLICXTDRRLHH-----HYK 495
Query: 110 DRDDQTRCNVWILDGDLYHKGLLKFSLDAVSLKDTLVMLVVDMSKPWTALD 160
+ D+ N W L H+ +L+ + SLK TL + ++ +SK WT D
Sbjct: 496 KKFDEKNLNAW--KSRLGHRHMLQVIV*ITSLKVTLPVYMLAVSKXWTQFD 642
>05468
Length = 1558
Score = 30.8 bits (68), Expect = 1.4, Method: Compositional matrix adjust.
Identities = 25/100 (25%), Positives = 50/100 (50%), Gaps = 4/100 (4%)
Frame = -3
Query: 70 VLLLGEDGAGKTSLIRKIQG---IEEYKKGRGLEYLYLNVHDEDRDDQTRCNVWILDGDL 126
+L++GE G GKTS+I++ + Y+ G+++ L V + D D R +W + G
Sbjct: 1532 ILVIGELGTGKTSIIKRYVHQFFSQHYRATIGVDFA-LKVLNWDADTLIRLQLWDIAGQE 1356
Query: 127 YHKGLLKFSLDAVSLKDTL-VMLVVDMSKPWTALDSLQKW 165
+ + V K+ + +V D+++ + D++ KW
Sbjct: 1355 RFGNMTR-----VYYKEAVGAFVVFDVTRA-STFDAVTKW 1254
>26083
Length = 432
Score = 29.6 bits (65), Expect = 3.3, Method: Composition-based stats.
Identities = 27/104 (25%), Positives = 44/104 (42%), Gaps = 3/104 (2%)
Frame = +1
Query: 70 VLLLGEDGAGKTSLIRKI---QGIEEYKKGRGLEYLYLNVHDEDRDDQTRCNVWILDGDL 126
++ LGE GKTSLI + Y+ G+++L ++ EDR R +W G
Sbjct: 85 LVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDR--TIRLQLWDTAGQE 258
Query: 127 YHKGLLKFSLDAVSLKDTLVMLVVDMSKPWTALDSLQKWASVVR 170
+ L+ ++D+ V +VV + KW VR
Sbjct: 259 RFRSLI-----PSYIRDSSVAVVVYDITNANSFHQTSKWIDDVR 375
>07465
Length = 1103
Score = 28.1 bits (61), Expect = 9.1, Method: Compositional matrix adjust.
Identities = 11/19 (57%), Positives = 15/19 (78%)
Frame = +3
Query: 285 TSVKENKNIDLVYKYIVQK 303
TSVKEN N+D V++Y+ K
Sbjct: 621 TSVKENMNVDEVFRYLADK 677
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000216911 | hsapiens_gene_ensembl |
Serine/threonine-protein kinase 6 (EC 2.7.11.1) (Aurora kinase A)
(Aurora-A) (Serine/threonine kinase 15) (Aurora/IPL1-related kinase 1)
(Aurora-related kinase 1) (hARK1) (Breast-tumor-amplified kinase).
[Source:Uniprot/SWISSPROT;Acc:O14965]
(403 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
21433 184 3e-69
15910 120 8e-28
03240 119 2e-27
01060 117 6e-27
00300 114 8e-26
30755 110 1e-24
18484 110 1e-24
18921 107 7e-24
12721 105 4e-23
14420 101 5e-22
01707 99 3e-21
14126 98 5e-21
09606 97 8e-21
06405 97 9e-21
09007 94 8e-20
13592 93 2e-19
13212 92 3e-19
01392 91 1e-18
01756 87 1e-17
13066 87 1e-17
11780 80 2e-17
04591 86 2e-17
01718 86 3e-17
17975 85 4e-17
31885 84 7e-17
27546 83 2e-16
00486 82 3e-16
21079 82 6e-16
00392 80 1e-15
01966 79 3e-15
19761 76 2e-14
19094 70 6e-14
26560 75 7e-14
29581 72 4e-13
20152 69 3e-12
27405 68 7e-12
26711 66 3e-11
19301 65 5e-11
38560 65 6e-11
14477 64 1e-10
04852 64 1e-10
06358 64 1e-10
04138 64 2e-10
21808 63 2e-10
00715 62 5e-10
14116 61 6e-10
28157 61 8e-10
12672 61 9e-10
07940 61 1e-09
03508 61 1e-09
26009 41 3e-09
12786 59 3e-09
18663 58 7e-09
28638 56 3e-08
02638 53 2e-07
11185 52 3e-07
25019 52 4e-07
29590 39 1e-06
27274 50 2e-06
31120 49 4e-06
37602 49 4e-06
07833 48 6e-06
32000 48 6e-06
07291 48 8e-06
01106 47 2e-05
18481 45 6e-05
32957 45 6e-05
31489 44 1e-04
16708 44 1e-04
17253 44 1e-04
20640 44 1e-04
07836 43 3e-04
20559 40 3e-04
17300 42 4e-04
11404 41 0.001
21210 40 0.001
21418 40 0.002
20160 39 0.006
00638 38 0.006
31789 37 0.018
36002 36 0.023
37063 35 0.043
20655 35 0.068
00394 35 0.079
18401 33 0.26
20773 32 0.48
21800 32 0.49
36481 32 0.51
19872 32 0.53
17932 28 0.76
16350 30 2.1
20513 29 2.9
17644 28 8.1
18929 28 9.8
>21433
Length = 590
Score = 184 bits (467), Expect(2) = 3e-69, Method: Compositional matrix adjust.
Identities = 93/136 (68%), Positives = 107/136 (78%)
Frame = +2
Query: 231 QRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLC 290
+RTA YI +L++AL YCH ++VIHRDIKPENLLLG G+LKIADFGWSVHAPSSRRTT+C
Sbjct: 167 KRTACYIYQLSSALEYCHYRKVIHRDIKPENLLLGLKGDLKIADFGWSVHAPSSRRTTMC 346
Query: 291 GTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPD 350
GTLDYLPPEM+EG+ HDE VDLWSLGVLCYEFLVG PP + + R P
Sbjct: 347 GTLDYLPPEMVEGKTHDENVDLWSLGVLCYEFLVGTPPLRPSPTRPPTPASPRWTSGSPS 526
Query: 351 FVTEGARDLISRLLKH 366
VT GARDLIS+LL+H
Sbjct: 527 IVTPGARDLISKLLRH 574
Score = 95.9 bits (237), Expect(2) = 3e-69, Method: Compositional matrix adjust.
Identities = 44/64 (68%), Positives = 54/64 (84%), Gaps = 1/64 (1%)
Frame = +3
Query: 176 HQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDE-QRTA 234
HQLRRE+EIQSHLRH NILR++GYFHD TRVYLILE+AP G +Y+ELQ+ KFDE ++ A
Sbjct: 3 HQLRREIEIQSHLRHDNILRMFGYFHDKTRVYLILEFAPKGELYKELQRCHKFDENEQHA 182
Query: 235 TYIT 238
Y +
Sbjct: 183 IYTS 194
>15910
Length = 1361
Score = 120 bits (302), Expect = 8e-28, Method: Compositional matrix adjust.
Identities = 61/177 (34%), Positives = 104/177 (58%), Gaps = 8/177 (4%)
Frame = +2
Query: 226 SKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLL---LGSAGELKIADFGWS-VHA 281
++ E+ A I+++ + + Y H+ V+HRD+KPENLL + +LK+ADFG S +
Sbjct: 449 GQYTEKDAARAISDILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLADFGLSRIIE 628
Query: 282 PSSRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRI 341
P + +T+CGT Y PE+++G + VD+WS+GV+ Y L G PF A E Y++I
Sbjct: 629 PEVQMSTVCGTPGYCAPEVLKGDKYTPSVDMWSVGVIAYILLCGYEPFFAENEFEMYRKI 808
Query: 342 SRVEFTFPD----FVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQ 394
+ E+ F + ++E A+D++ +LL +P +R E L PW+ ++K +N +
Sbjct: 809 IKGEYKFDEEYWSEISENAKDVVRKLLVIDPKKRLTATEALRLPWVKGVATKTTNME 979
>03240
Length = 1683
Score = 119 bits (298), Expect = 2e-27, Method: Compositional matrix adjust.
Identities = 86/283 (30%), Positives = 133/283 (46%), Gaps = 52/283 (18%)
Frame = -3
Query: 133 FEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPN 192
FE + LG G FG V L R+ + + A+K L K+ + K ++ E +I + +
Sbjct: 1285 FEKIKTLGVGAFGEVSLCRKNDTGMLYAMKTLRKSDVLKRNQVAHVKAERDILAEADNEW 1106
Query: 193 ILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRV 252
+++LY F D +Y +++Y P G + L ++ DE Y+ EL A+ H
Sbjct: 1105 VVKLYYSFQDHNYLYFVMDYVPGGDLMGLLIRMEILDEPLARFYVAELVQAIESVHRMGF 926
Query: 253 IHRDIKPENLLLGSAGELKIADFG------WS----------VHA--------------- 281
IHRDIKP+N+L+ G +K+ DFG W+ HA
Sbjct: 925 IHRDIKPDNILIDRNGHIKLTDFGLCTGFRWTHNSKYYQRDGTHARQDSMEVKCQLDEQC 746
Query: 282 ------PSSRRT---------TLCGTLDYLPPEMIEGRM--HDEKVDLWSLGVLCYEFLV 324
P RR +L GT +Y+ PE++ R+ + D WS+GV+ +E LV
Sbjct: 745 QCEILKPLERRRKREQRCLAHSLVGTPNYIAPEVL-SRLGGYTSVCDWWSVGVILFEMLV 569
Query: 325 GKPPFEANTYQET-YKRIS---RVEFTFPDFVTEGARDLISRL 363
G PPF ANT ET YK I+ ++ +++ A+DLI RL
Sbjct: 568 GHPPFYANTPAETQYKVINWKDMLKIPRESNLSQPAKDLILRL 440
>01060
Length = 1800
Score = 117 bits (294), Expect = 6e-27, Method: Compositional matrix adjust.
Identities = 83/305 (27%), Positives = 145/305 (47%), Gaps = 36/305 (11%)
Frame = +1
Query: 129 ALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHL 188
AL D + +G+G +G VY R + + LA+K + + + + GV RE+ + L
Sbjct: 67 ALSDLTDFQKIGEGTYGVVYKCRHRATGRKLAMKKI-RLRGSEDGVPSSAIREIAMLREL 243
Query: 189 RHPNILRLYGYFHDATRVYLILEY--APLGTVYRELQKLSKFDEQRTATYITELANALSY 246
RH NI+ L + R++L+ E+ L + + D + +Y+ ++ + +
Sbjct: 244 RHTNIVCLEDVIMEDERLFLVFEFLSMDLKMYIDKFPEGVVLDRRLVKSYVFQIVTGIXF 423
Query: 247 CHSKRVIHRDIKPENLLLGSAGELKIADFGW--SVHAPSSRRTTLCGTLDYLPPEMIEG- 303
CH +R++HRD+KP+NLL+ G +KIADFG + P T TL Y PE++ G
Sbjct: 424 CHQRRIVHRDLKPQNLLINHTGAIKIADFGMARTFALPVRAYTHEVVTLWYRAPEILMGA 603
Query: 304 RMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRV-----EFTFPDF------- 351
+ VD+WS+G + + L+ P F+ ++ + +I R+ E T+P+F
Sbjct: 604 SKYSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKLPAFN 783
Query: 352 -----------------VTEGARDLISRLLKHNPSQRPMLREVLEHPWI--TANSSKPSN 392
+ DLI R LK +P+QR +++L+H + S KP +
Sbjct: 784 GMFPLWKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYFLNVDTSVKPVD 963
Query: 393 CQNKE 397
+ E
Sbjct: 964 VPSPE 978
>00300
Length = 2318
Score = 114 bits (285), Expect = 8e-26, Method: Compositional matrix adjust.
Identities = 74/257 (28%), Positives = 125/257 (48%), Gaps = 10/257 (3%)
Frame = -1
Query: 136 GRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILR 195
G +G+G+FG VY A + ++ALK + K Q ++ E++I ++H N+++
Sbjct: 1643 GNKIGEGQFGKVYTAVNMSTGELMALKEM-KFQPNDLQQLREMCDEIKIFEGIQHENLVK 1467
Query: 196 LYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHR 255
YG + + +EY GT+ E K+ E Y E+ A+++ H ++HR
Sbjct: 1466 YYGVEVHKDEMLMFMEYCDTGTI-EEAAKMG-LPEYLIRRYTREIVLAVNHLHENSIVHR 1293
Query: 256 DIKPENLLLGSAGELKIADFGWSVHAPSSRRT-----TLCGTLDYLPPEMI---EGRMHD 307
DIK N+ L S G +K+ DFG SV S L GT Y+ PE+ + +
Sbjct: 1292 DIKGANIFLTSNGHVKLGDFGCSVKLKSHTTMPGEFHNLVGTTAYMAPEVFTQNDQGGYG 1113
Query: 308 EKVDLWSLGVLCYEFLVGKPPFE--ANTYQETYKRISRVEFTFPDFVTEGARDLISRLLK 365
D+WSLG + E GK P+ N YQ YK + PD ++ + + ++
Sbjct: 1112 RAADIWSLGCVVIEMATGKRPWHDLDNNYQIMYKVGIGHKPAVPDSLSVEGKHFLDLIMC 933
Query: 366 HNPSQRPMLREVLEHPW 382
H+P+QR + ++L+H +
Sbjct: 932 HDPAQRALASQLLDHTF 882
>30755
Length = 1137
Score = 110 bits (275), Expect = 1e-24, Method: Compositional matrix adjust.
Identities = 60/165 (36%), Positives = 91/165 (55%), Gaps = 7/165 (4%)
Frame = +2
Query: 228 FDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRT 287
F E+RT Y E+ +AL Y HS+ +I+RD+K ENLLL G +K+ADFG + RT
Sbjct: 23 FTEERTRFYGAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCKEDITYGRT 202
Query: 288 T--LCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVE 345
T CGT +YL PE+++ + VD W GV+ YE + G+ PF + + I +
Sbjct: 203 TKTFCGTPEYLAPEVLDDNDYGRAVDWWGTGVVMYEMICGRLPFYNRDHDVLFTLILVED 382
Query: 346 FTFPDFVTEGARDLISRLLKHNPSQR-----PMLREVLEHPWITA 385
FP +T+ A+ L+S LL +P R ++E+ HP+ +
Sbjct: 383 VKFPRNITDEAKSLLSGLLAKDPRNRLGGGQDDVKEIQAHPFFAS 517
>18484
Length = 635
Score = 110 bits (275), Expect = 1e-24, Method: Compositional matrix adjust.
Identities = 57/156 (36%), Positives = 89/156 (57%), Gaps = 2/156 (1%)
Frame = +1
Query: 218 VYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGW 277
+YR +Q+ KF E A Y E+A L + H + +I+RD+K +N++L S G +KIADFG
Sbjct: 7 MYR-IQQEGKFKEPVAAFYAAEIAVGLFFLHDQGIIYRDLKLDNVMLDSEGHIKIADFGM 183
Query: 278 SVHAPSSRRTT--LCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQ 335
+ TT CGT DY+ PE++ + + + VD W+ GVL +E L G+PPF+
Sbjct: 184 CKEGMTGDATTRTFCGTPDYIAPEIVLYQPYSKSVDWWAYGVLLFEMLAGQPPFDGEDED 363
Query: 336 ETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQR 371
E + I+ ++P ++ A L LL NP++R
Sbjct: 364 ELFSSITDHNVSYPKAMSREAVSLCKGLLMKNPTKR 471
>18921
Length = 697
Score = 107 bits (268), Expect = 7e-24, Method: Compositional matrix adjust.
Identities = 64/199 (32%), Positives = 109/199 (54%), Gaps = 3/199 (1%)
Frame = +2
Query: 133 FEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPN 192
F+I LG+G +G+V+ + K++ +LA+K Q+ ++ +E+ I
Sbjct: 35 FDILGKLGEGSYGSVFKSLHKETGQVLAIK-----QVPVDTDLQEIIKEISIMQQCDSKY 199
Query: 193 ILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSK-FDEQRTATYITELANALSYCHSKR 251
I++ YG + T +++++EY G+V ++ +K E+ AT + L Y HS+R
Sbjct: 200 IVKYYGSYFKNTDLWIVMEYCGAGSVSDIMRLRNKTLVEREIATILYYTLKGLXYLHSRR 379
Query: 252 VIHRDIKPENLLLGSAGELKIADFGWS--VHAPSSRRTTLCGTLDYLPPEMIEGRMHDEK 309
IHRDIK N+LL + G K+ADFG + + ++R T+ GT ++ PE+I+ +D
Sbjct: 380 KIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTPYWMAPEVIQEIGYDCV 559
Query: 310 VDLWSLGVLCYEFLVGKPP 328
D+WSLG+ E GKPP
Sbjct: 560 ADIWSLGITALEMAEGKPP 616
>12721
Length = 821
Score = 105 bits (261), Expect = 4e-23, Method: Compositional matrix adjust.
Identities = 69/247 (27%), Positives = 123/247 (49%), Gaps = 5/247 (2%)
Frame = +1
Query: 130 LEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLR 189
L+DF +G+G G V +A + + +A+K K L K L EV +
Sbjct: 94 LDDF---MKIGEGSTGIVCIATSRDGR-QMAVK---KMDLRKQQRRELLFNEVVVMRDYH 252
Query: 190 HPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHS 249
HPNI+ +Y + +++++E+ G ++ ++ DE + AT AL++ H+
Sbjct: 253 HPNIVEMYNSYLVNDELWVVMEFME-GGALTDIVTNNRMDEVQIATVCRACLKALAFLHA 429
Query: 250 KRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSS--RRTTLCGTLDYLPPEMIEGRMHD 307
VIHRDIK +++LL G++K+ DFG+ +R +L GT ++ PE+I +
Sbjct: 430 NGVIHRDIKSDSILLSHDGKVKLXDFGFCAQVTQDLQKRKSLVGTPYWMAPEVISRLPYG 609
Query: 308 EKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRV---EFTFPDFVTEGARDLISRLL 364
+VD+WSLG++ E + +PPF + +RI + + ++ + I R+L
Sbjct: 610 PEVDIWSLGIMVMEMIDAEPPFFNEPPLQAMRRIRDMPPPKLRNTHKISPRLQGFIDRML 789
Query: 365 KHNPSQR 371
+P QR
Sbjct: 790 VRDPHQR 810
>14420
Length = 528
Score = 101 bits (252), Expect = 5e-22, Method: Compositional matrix adjust.
Identities = 48/151 (31%), Positives = 87/151 (57%), Gaps = 2/151 (1%)
Frame = +2
Query: 181 EVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITEL 240
E+ + ++PNI+ + +++++E+ G++ + + + DE + A E
Sbjct: 50 EILVMRENQNPNIVNYLDSYLVGEELWVVMEFLAGGSLTDVVTE-TCMDEGQIAAVCREC 226
Query: 241 ANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAP--SSRRTTLCGTLDYLPP 298
AL + H +VIHRDIK +N+LLG G +K+ DFG+ S+R+T+ GT ++ P
Sbjct: 227 LQALEFLHENQVIHRDIKSDNILLGMDGSVKLTDFGFCAQLSPEQSKRSTMVGTPYWMAP 406
Query: 299 EMIEGRMHDEKVDLWSLGVLCYEFLVGKPPF 329
E++ + + VD+WSLGV+C E + G+PP+
Sbjct: 407 EVVTRKQYGPTVDIWSLGVMCIEMIEGEPPY 499
>01707
Length = 757
Score = 99.0 bits (245), Expect = 3e-21, Method: Compositional matrix adjust.
Identities = 58/201 (28%), Positives = 108/201 (53%), Gaps = 4/201 (1%)
Frame = +1
Query: 130 LEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLR 189
+E +E +G+G +G V+ R K++ ++A+K +++ + ++ RE+ + L+
Sbjct: 61 MEKYEKIGKIGEGSYGVVFKCRNKETSQLVAIKKFVESE-DDPLIKKIAMREIRMLKQLK 237
Query: 190 HPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSK-FDEQRTATYITELANALSYCH 248
HPN++RL F R++L+ +Y T+ EL + + E I + A+++CH
Sbjct: 238 HPNLVRLIEVFRRKKRLHLVFDYVD-HTLLNELDRYPRGLPEPMVKRIIYQTLLAVNFCH 414
Query: 249 SKRVIHRDIKPENLLLGSAGELKIADFGWS--VHAPSSRRTTLCGTLDYLPPEMIEGRM- 305
IHRD+KPEN+L+ G++K+ DFG++ + P T T Y PE++ G
Sbjct: 415 QYNTIHRDVKPENILITRQGQVKLCDFGFARILTGPGDEYTDYVATRWYRAPELLVGDTQ 594
Query: 306 HDEKVDLWSLGVLCYEFLVGK 326
+ VD+W++G + E L G+
Sbjct: 595 YGPPVDVWAIGCVFAELLTGQ 657
>14126
Length = 1265
Score = 98.2 bits (243), Expect = 5e-21, Method: Compositional matrix adjust.
Identities = 86/332 (25%), Positives = 146/332 (43%), Gaps = 46/332 (13%)
Frame = +3
Query: 116 SKQKNEESKKRQWALEDFEIGRPLGKGKFGNVYLARE--KQSKFILALKVLFKAQLEKAG 173
S+ + S++R + +E +G G +G VY AR+ Q +F+ ++ E G
Sbjct: 144 SESAAKMSRRRDSTEQKYEEVAVIGNGAYGTVYKARDLRNQGEFVAMKRIRLNNTEE--G 317
Query: 174 VEHQLRREVEIQSHLR---HPNILRLYGYFHDAT-----RVYLILEYA--PLGTVYRELQ 223
+ RE+ + L HPN++RL H+ R+ L+ EY L T Y
Sbjct: 318 MPMMAIREISMLKQLEQYEHPNVVRLLDVSHNTITDREIRLNLVFEYIEHDLAT-YLAKC 494
Query: 224 KLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS-VHAP 282
R + +L N + + HS R++HRD+KP+NLL+ G LK+ADFG + +++
Sbjct: 495 PSPGLGPDRIKDLMLQLLNGVDFLHSNRIVHRDLKPQNLLISKDGRLKLADFGLARIYSF 674
Query: 283 SSRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRIS 342
TT+ TL Y PE++ + VD+WS G + E + F+ ++ + K+I
Sbjct: 675 HMALTTVVVTLWYRSPEVLMQAEYGTSVDIWSCGCIFAELFTRRALFKGSSEFDQLKKIF 854
Query: 343 RV-----EFTFPDFVTEG----------------------ARDLISRLLKHNPSQRPMLR 375
V +P+ V+ A+DL+ ++L +R R
Sbjct: 855 EVIGLPPAGDWPEGVSVHRNSFRPTPPVPLQTLVPEMDPQAKDLMEKMLVFKSGRRISSR 1034
Query: 376 EVLEHPWITAN------SSKPSNCQNKESASK 401
E L HP++ + SS S +N S +
Sbjct: 1035ESLLHPYLRDDLDSIRTSSSLSTSENDSSDGR 1130
>09606
Length = 1300
Score = 97.4 bits (241), Expect = 8e-21, Method: Compositional matrix adjust.
Identities = 66/285 (23%), Positives = 126/285 (44%), Gaps = 34/285 (11%)
Frame = -3
Query: 130 LEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLR 189
+E+F + LGKG+ +Y R K + +A+ + K + ++ V + +
Sbjct: 1118 MENFVLYEELGKGEHSIIYKGRRKGTINFVAIHCIEKCK------RPEVTNTVRMTHDIS 957
Query: 190 HPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHS 249
HPN+++ + ++ + ++L++E G++ L + E + L L Y HS
Sbjct: 956 HPNVVQFHEWYETSNHLWLVVELCTGGSLADILAQDHHLPETSIRDFGIHLVTGLHYIHS 777
Query: 250 KRVIHRDIKPENLLLGSAGELKIADFG----------------------WSVHAPSS--R 285
++ D++P +LL ++G LK ADFG W++ + +
Sbjct: 776 LGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQWNIQSAEEMMK 597
Query: 286 RTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVE 345
+ G+ Y+ PE+ +G DLW+LG + YE G PPF TY T ++ E
Sbjct: 596 QVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSGHPPFLGETYDITKDKVLNKE 417
Query: 346 FTFPDFVTEGAR----------DLISRLLKHNPSQRPMLREVLEH 380
F P +G+R +L+ LL+ + ++R +++H
Sbjct: 416 FPLPK--VKGSRLSAKPSPEFLNLLESLLQKDSTRRLSWASLVKH 288
>06405
Length = 1965
Score = 97.4 bits (241), Expect = 9e-21, Method: Compositional matrix adjust.
Identities = 68/260 (26%), Positives = 118/260 (45%), Gaps = 9/260 (3%)
Frame = +1
Query: 127 QWALEDFEIGRP--LGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEI 184
+W +E EI LG G++G+VY A K+ I+A+K L E + E I
Sbjct: 241 RWEIERTEIAMKHRLGGGQYGDVYEAMWKRYNKIVAVKTL----KEDTMALNDFLEEAAI 408
Query: 185 QSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTA-TYI-TELAN 242
++HPN+++L G Y++ E+ P G + L+ ++ + TA Y+ T++A+
Sbjct: 409 MKEMKHPNLVQLLGVCTREPPFYIVTEFMPHGNLLDYLRSSTREENGPTALMYMATQIAS 588
Query: 243 ALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGT---LDYLPPE 299
++Y +K IHRD+ N L+ + +K+ADFG + T G + + PE
Sbjct: 589 GMAYLETKNFIHRDLAARNCLVADSNMVKVADFGLARLMKDDTYTAHIGAKFPIKWTAPE 768
Query: 300 MIEGRMHDEKVDLWSLGVLCYEFLV-GKPPFEANTYQETYKRISR-VEFTFPDFVTEGAR 357
+ + D+W+ GVL +E G P+ E Y + R P
Sbjct: 769 GLAFNRFSTRSDIWAFGVLLWELATYGMSPYPGVELTEVYHLLERGYRMERPPGTPADVY 948
Query: 358 DLISRLLKHNPSQRPMLREV 377
L+ + + +P RP +E+
Sbjct: 949 ILMLKCWQWDPKDRPTFKEI 1008
>09007
Length = 1440
Score = 94.4 bits (233), Expect = 8e-20, Method: Compositional matrix adjust.
Identities = 71/264 (26%), Positives = 122/264 (46%), Gaps = 20/264 (7%)
Frame = -1
Query: 135 IGRPLGKGKFGNVYLA---REKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHP 191
+ + LG+G FG V A E K +A+K L K ++ K G E +E I L H
Sbjct: 867 LSKSLGQGHFGTVRQAIWTAESGEKVQVAVKCLSKDKIHKDGQE--FLKETAIMQMLDHE 694
Query: 192 NILRLYGYFHD-ATRVYLILEYAPLGTVYRELQKLS---KFDEQRTATYITELANALSYC 247
NI+R+YG D + L+ E AP+ ++ ++++S F R + ++ + +SY
Sbjct: 693 NIVRVYGVVMDNGADIMLVTELAPMRSLLECVKEVSARVDFSVPRLCDFSQQVCDGMSYL 514
Query: 248 HSKRVIHRDIKPENLLLGSAGELKIADFGWSV-------HAPSSRRTTLCGTLDYLPPEM 300
SKR++HRD+ N+LL S ++KI+D G S + S + L + + PE
Sbjct: 513 ESKRLVHRDLAARNILLFSKSKVKISDVGVSGALGAGKEYYQSQQTIHLQNAVAWCAPES 334
Query: 301 IEGRMHDEKVDLWSLGVLCYEFLV-GKPPFEANTYQETYKRIS-----RVEFTFPDFVTE 354
D+W+ GVL +EF G P+ Q+ + + R+E PD +
Sbjct: 333 FRNLCFSSASDVWAFGVLLWEFFTHGFQPWAGLNGQQIMEAVDAPQSQRLE--QPDLCPK 160
Query: 355 GARDLISRLLKHNPSQRPMLREVL 378
++ + + P +RP ++
Sbjct: 159 EYYAVMLKCWEQEPQRRPTFSQLF 88
>13592
Length = 980
Score = 93.2 bits (230), Expect = 2e-19, Method: Compositional matrix adjust.
Identities = 68/270 (25%), Positives = 128/270 (47%), Gaps = 14/270 (5%)
Frame = +2
Query: 139 LGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYG 198
+G+G+FG VY A + ++A+K + E +++ + E++I ++H N++R YG
Sbjct: 8 IGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETRALKN-VAEELKILEGIKHKNLVRYYG 184
Query: 199 YFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIK 258
+ + +E GT+ ++ E + + +L + ++ H ++HRDIK
Sbjct: 185 IEVHREELLIFMELCSEGTLESLVELTGGLPEALSRRFTAQLLSGVAELHKHGIVHRDIK 364
Query: 259 PENL-LLGSAGELKIADFGWSVHAPSSRRTTL-------CGTLDYLPPEMI---EGRMHD 307
N+ L+ + LK+ DFG +V + TT+ GT Y+ PE+ H
Sbjct: 365 TANIFLVDGSNSLKLGDFGSAVKIQA--HTTVPGELQGYVGTQAYMAPEVFTKTNSDGHG 538
Query: 308 EKVDLWSLGVLCYEFLVGKPP---FEANTYQETYKRISRVEFTFPDFVTEGARDLISRLL 364
D+WS+G + E GK P F++N +Q +K + P+ +++ D I L
Sbjct: 539 RLADIWSVGCVVVEMASGKRPWAQFDSN-FQIMFKVGMGEKPQAPESLSQEGHDFIDHCL 715
Query: 365 KHNPSQRPMLREVLEHPWITANSSKPSNCQ 394
+H+P QR E+LE + + + N +
Sbjct: 716 QHDPKQRLSAIELLEQNFCKSGRDEECNSE 805
>13212
Length = 1067
Score = 92.4 bits (228), Expect = 3e-19, Method: Compositional matrix adjust.
Identities = 60/188 (31%), Positives = 96/188 (51%), Gaps = 10/188 (5%)
Frame = -1
Query: 206 VYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLG 265
V+ +L + L ++ +L+K E + E+ AL + H VIHRDIK N+LL
Sbjct: 1049 VFRVLWWGALDSIMVDLEK--PMTEAQICYVCHEMCMALDFLHRHHVIHRDIKAGNVLLT 876
Query: 266 SAGELKIADFGWSVHAPSS--RRTTLCGTLDYLPPEMI-----EGRMHDEKVDLWSLGVL 318
GE+K+ADFG S + +R T GT ++ PE++ + +D K D+WSLGV
Sbjct: 875 IDGEVKLADFGVSAKNTQTQQKRDTFIGTPYWMAPEVVLCETLKDTPYDFKADIWSLGVT 696
Query: 319 CYEFLVGKPPFEANTYQETYKRISRVE---FTFPDFVTEGARDLISRLLKHNPSQRPMLR 375
EF +PP + +I + + P T+ +D I++ L +P+ RP
Sbjct: 695 LIEFAQIEPPNKEMHPMRVLIKIHKSDPPTLEKPKKWTKLFKDFIAKCLVKDPNLRPTAA 516
Query: 376 EVLEHPWI 383
E+LEHP++
Sbjct: 515 ELLEHPFM 492
>01392
Length = 1806
Score = 90.5 bits (223), Expect = 1e-18, Method: Compositional matrix adjust.
Identities = 57/189 (30%), Positives = 90/189 (47%), Gaps = 34/189 (17%)
Frame = -1
Query: 230 EQRTATYITELANALSYCHSKRVIHRDIKPENLL---LGSAGELKIADF----GWSVHAP 282
E+ + + +A AL + HSK + HRD+KPEN+L L +KI DF G S
Sbjct: 1794 EREASLVVRHIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGISCDGD 1615
Query: 283 SSRRTTL---CGTLDYLPPEMIEGRM-----HDEKVDLWSLGVLCYEFLVGKPPFEANTY 334
++ L G+ +Y+ PE+++ + +D++ DLWSLG++ Y L G PPF
Sbjct: 1614 GTKTPELLTPVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILYIMLCGYPPFYGQCG 1435
Query: 335 QET---------------YKRISRVEFTFPD----FVTEGARDLISRLLKHNPSQRPMLR 375
++ + I + FP ++ A+DLI LL P +R
Sbjct: 1434 EDCGWNRGEACHDCQDMLFNSIQDGHYKFPSQEWTSISSSAKDLIRHLLVREPRKRYSAA 1255
Query: 376 EVLEHPWIT 384
+VL+HPWI
Sbjct: 1254 DVLKHPWIC 1228
>01756
Length = 1858
Score = 87.0 bits (214), Expect = 1e-17, Method: Compositional matrix adjust.
Identities = 66/222 (29%), Positives = 106/222 (47%), Gaps = 16/222 (7%)
Frame = -3
Query: 139 LGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYG 198
+G+G FG V+ AR K++K ++A+K + EK G RE++I L H N++ L
Sbjct: 1718 IGQGTFGEVFKARCKKTKQVVAMKKVLMDN-EKEGFPITALREIKILQLLNHENVVDLIE 1542
Query: 199 YFH----DATR----VYLILEYA--PLGTVYRELQKLSKFDEQRTATYITELANALSYCH 248
A R YL+ E+ L + + + E + + +L N L Y H
Sbjct: 1541 ICSTKATSANRYKSMFYLVFEFCEHDLAGLLSNMSVVFNLPEIKEV--MKQLMNGLYYIH 1368
Query: 249 SKRVIHRDIKPENLLLGSAGELKIADFG----WSVHAPS-SRRTTLCGTLDYLPPEMIEG 303
+++HRD+K N+L+ G LK+ADFG +SV+ +R T TL Y PPE++ G
Sbjct: 1367 RNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRPPELLLG 1188
Query: 304 -RMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRV 344
R + +D W G + E P + T Q I+++
Sbjct: 1187 DRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQNQLTLITQL 1062
>13066
Length = 551
Score = 87.0 bits (214), Expect = 1e-17, Method: Compositional matrix adjust.
Identities = 50/164 (30%), Positives = 87/164 (53%), Gaps = 6/164 (3%)
Frame = +3
Query: 159 LALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTV 218
LA K++ K + VE RE+++ + L HP I++++ + ++ + +A G +
Sbjct: 60 LACKIIDKEKAPVDFVEKFFPRELDLLTKLDHPYIIQIHSILQRXPKNFIFMRFAERGDL 239
Query: 219 YRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS 278
+Q++ E++ + ++ AL+Y HS V HRD+K EN+LL S +K+ADFG++
Sbjct: 240 LTYIQEVGFVKEKQAKIWFYQMTTALNYLHSYDVAHRDLKCENILLSSHFNVKLADFGFA 419
Query: 279 VHAPSS-----RRTTLCGTLDYLPPEMIEGRMHDEKV-DLWSLG 316
+ T CG+ Y PE++ G + KV D WSLG
Sbjct: 420 CACITESGEKYMSRTYCGSAAYAAPEIVYGAPYAPKVADAWSLG 551
>11780
Length = 1713
Score = 80.1 bits (196), Expect(2) = 2e-17, Method: Compositional matrix adjust.
Identities = 57/202 (28%), Positives = 100/202 (49%), Gaps = 7/202 (3%)
Frame = +3
Query: 121 EESKKRQW--ALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQL 178
+E K W A +D EIG +GKG FG+VY + V K +K E
Sbjct: 561 QEFKSGGWVIAXQDLEIGEAIGKGDFGDVYKGMYRGQP------VAIKQLKDKDRGEQSF 722
Query: 179 RREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSK--FDEQRTATY 236
+E + + LRH N++RL G T ++L+ E+ G + L+ + ++ +
Sbjct: 723 LQEASVMTSLRHDNLVRLIGVVLGET-IFLVTEFMGKGNLVEYLRSRGRSVITKKDQINF 899
Query: 237 ITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYL 296
T+ A+ Y SKR++HRD+ N+L+ G+ K++DFG + S +T++ + +
Sbjct: 900 ATDTCAAMEYLESKRLVHRDLAARNVLVHDDGKAKVSDFGLAKFGDFS-QTSVKFPIKWT 1076
Query: 297 PPEMI-EGRMHDE--KVDLWSL 315
PE + E ++H + V+LW +
Sbjct: 1077APEALRENKIH*QVRHVELWHI 1142
Score = 26.6 bits (57), Expect(2) = 2e-17, Method: Compositional matrix adjust.
Identities = 16/72 (22%), Positives = 33/72 (45%), Gaps = 2/72 (2%)
Frame = +1
Query: 309 KVDLWSLGVLCYE-FLVGKPPFEANTYQETYKRISR-VEFTFPDFVTEGARDLISRLLKH 366
K D+WS G+L +E + G+ P+ + + R P+ ++ + +
Sbjct: 1114 KSDMWSFGILLWEIYSFGRVPYPRIPLTDVVMHVERGYRMEAPEGCPPEIYSIMKQAWEL 1293
Query: 367 NPSQRPMLREVL 378
+P++RP + VL
Sbjct: 1294 DPNERPTFKSVL 1329
>04591
Length = 1117
Score = 86.3 bits (212), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 60/184 (32%), Positives = 88/184 (47%), Gaps = 12/184 (6%)
Frame = -2
Query: 171 KAGVEHQLRREVEIQSHLRHPNILRLYGYFHD--------ATRVYLILEYAP--LGTVYR 220
K G RE++I L H N+++L H + YLI EY L +
Sbjct: 1101 KEGFPITALREIKILQQLEHENVVQLQEICHTQAGPYNRYKSTFYLIFEYCDYDLAGLLN 922
Query: 221 ELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSV- 279
L+ KF +++L N L Y H+K+++HRDIK N+LL G LK+ADFG S
Sbjct: 921 NLR--VKFSLADKKNLMSQLLNGLFYIHTKQILHRDIKAANILLTRDGVLKLADFGLSRP 748
Query: 280 HAPSSRRTTLCGTLDYLPPEMIEG-RMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETY 338
S R T TL Y PPE++ G R + ++D+W +G + E KP + + Q
Sbjct: 747 WVKSKRLTNRVVTLWYRPPELLLGEREYGPEIDMWGVGCIMAEMWSRKPLMQGRSEQHQL 568
Query: 339 KRIS 342
I+
Sbjct: 567 SLIT 556
>01718
Length = 959
Score = 85.9 bits (211), Expect = 3e-17, Method: Compositional matrix adjust.
Identities = 62/209 (29%), Positives = 99/209 (47%), Gaps = 11/209 (5%)
Frame = +3
Query: 130 LEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLR 189
L+DF I +G G F V+ + + ++ALK+ H + REV++ + L+
Sbjct: 147 LDDF-ICEKIGAGFFSEVFKVTHRITGQVMALKMN-----TMTSNRHNMLREVQLLNRLQ 308
Query: 190 HPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTAT----YITELANALS 245
H NILR G +++ + EY P G + Q L K DE+ T LA L
Sbjct: 309 HANILRFMGVCVHEGQLHALTEYIPSGNLE---QLLEKKDEELPWTQRIQLTLGLARGLD 479
Query: 246 YCHSKRVIHRDIKPENLLL----GSAGELKIADFGWSVHAP---SSRRTTLCGTLDYLPP 298
Y HS R IHRD+ +N+L+ IADFG + P + G+ ++ P
Sbjct: 480 YLHSTRFIHRDLTSKNILIRREDNHGYHAVIADFGLATKIPDPLDKEKLPTVGSPYWMAP 659
Query: 299 EMIEGRMHDEKVDLWSLGVLCYEFLVGKP 327
E++ G ++E+ DL+S+G++ E P
Sbjct: 660 EVLNGHFYNERADLFSVGIIMCEITARIP 746
>17975
Length = 449
Score = 85.1 bits (209), Expect = 4e-17, Method: Compositional matrix adjust.
Identities = 51/137 (37%), Positives = 80/137 (58%), Gaps = 2/137 (1%)
Frame = +3
Query: 144 FGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDA 203
F V LAR + +A+KV+ K +L++ H L +EV ++HPN++RLY
Sbjct: 6 FAVVKLARHVFTGEKVAVKVIDKTKLDEVSRSH-LFQEVRCMKLVQHPNVVRLYEVIDTQ 182
Query: 204 TRVYLILEYAPLGTVYRELQKLSKFDEQRTAT-YITELANALSYCHSKRVIHRDIKPENL 262
T++YLILE G +Y + + S E++ A Y ++ A+SYCH V+HRD+KPEN+
Sbjct: 183 TKLYLILELGDGGDMYDYIMRHSGGLEEKLAKRYFRQIVEAISYCHKLHVVHRDLKPENV 362
Query: 263 LLGSA-GELKIADFGWS 278
+ G +K+ DFG+S
Sbjct: 363 VFFEKPGLVKLTDFGFS 413
>31885
Length = 529
Score = 84.3 bits (207), Expect = 7e-17, Method: Compositional matrix adjust.
Identities = 48/158 (30%), Positives = 81/158 (51%), Gaps = 6/158 (3%)
Frame = -2
Query: 182 VEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELA 241
V++ + L HP ++ L+ F D ++++++ G + +Q+ F E Y+ +LA
Sbjct: 519 VDMLTRLDHPFLVNLWYAFQDEEDLFMVVDLFLGGDLRYHMQQEVSFREDCVKFYLCQLA 340
Query: 242 NALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSR-RTTLCGTLDYLPPEM 300
L Y S++++HRDIKP+N+LL G + DF + T+ GT Y+ PE+
Sbjct: 339 LVLDYLRSQKIVHRDIKPDNILLDEQGHCHVTDFNIATQLEDDELATSTSGTRPYMAPEV 160
Query: 301 I-----EGRMHDEKVDLWSLGVLCYEFLVGKPPFEANT 333
E R + VD WSLGV +E L + PF ++
Sbjct: 159 YGVAINERRGYGFPVDWWSLGVSLFELLKKRRPFSVHS 46
>27546
Length = 426
Score = 82.8 bits (203), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 42/120 (35%), Positives = 70/120 (58%)
Frame = -1
Query: 159 LALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTV 218
LA K++ KA+ V+ RE+EI + L HPNI++++ ++++ + YA G +
Sbjct: 396 LACKIIDKAKAPIDFVKKFFPRELEILTRLDHPNIIQIHSILQRGPKIFIFMRYAEKGDM 217
Query: 219 YRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS 278
++K DE +T + ++A AL Y HS + HRD+K EN+LL +KIADFG++
Sbjct: 216 LSHIKKTGPIDEAQTKVWFFQMAKALQYLHSHDIAHRDLKCENILLSKRLNVKIADFGFA 37
>00486
Length = 797
Score = 82.0 bits (201), Expect = 3e-16, Method: Compositional matrix adjust.
Identities = 35/84 (41%), Positives = 53/84 (63%)
Frame = -2
Query: 288 TLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFT 347
T CGT++Y+ PE++ H + VD WSLG L Y+ L G PPF A ++T +I + +
Sbjct: 781 TFCGTIEYMAPEILTRTGHGKAVDWWSLGALMYDMLTGSPPFTAENRKKTIDKILKGKLN 602
Query: 348 FPDFVTEGARDLISRLLKHNPSQR 371
P ++T AR LI +LL+ NP++R
Sbjct: 601 LPPYLTNEARGLIKKLLRKNPAER 530
>21079
Length = 878
Score = 81.6 bits (200), Expect = 6e-16, Method: Compositional matrix adjust.
Identities = 42/148 (28%), Positives = 79/148 (53%), Gaps = 4/148 (2%)
Frame = +1
Query: 190 HPNILRLYGYFHDATRVYLILEYAPLGTVY-RELQKLSKFDEQRTATYITELANALSYCH 248
HP +L L+ F + L++E+ G ++ R ++ E+ ++ ++ + + Y H
Sbjct: 1 HPKLLMLWDAFEAPRTMVLVMEFVGAGELFERVIRDDFVLTERDCVHFVRQICSGVGYMH 180
Query: 249 SKRVIHRDIKPENLLLGS--AGELKIADFGWS-VHAPSSRRTTLCGTLDYLPPEMIEGRM 305
++ ++H D+KPEN+L S + ++KI DFG + + P L GT +++ PE++
Sbjct: 181 TQSILHLDLKPENVLCVSDNSNQIKIIDFGLARFYKPGDSLQVLFGTPEFIAPEVVNYDE 360
Query: 306 HDEKVDLWSLGVLCYEFLVGKPPFEANT 333
+ D+WS+GV+CY L G P T
Sbjct: 361 INFTTDMWSIGVICYILLSGLSPSRVTT 444
>00392
Length = 668
Score = 80.5 bits (197), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 48/175 (27%), Positives = 91/175 (52%), Gaps = 9/175 (5%)
Frame = +3
Query: 177 QLRREVEIQSHLRHPNILRLYGYFHDATR-----VYLILEYAPLGTVYRELQKLSKFDEQ 231
+ + E E+ L+HPNI+R + Y+ + + L+ E GT+ L++ K + +
Sbjct: 69 RFKEEAEMLKELQHPNIVRFFDYWEEHNHRNRKVIILVTELMTSGTLKTYLKRFKKPNVK 248
Query: 232 RTATYITELANALSYCHSKR--VIHRDIKPENLLL-GSAGELKIADFGWSVHAPSSRRTT 288
+ ++ L + H++ VIHRD+K +N+ + G G +KI D G + S +
Sbjct: 249 ILKNWCRQVLKGLYFLHTRTPPVIHRDLKCDNIFITGPTGSVKIGDLGLATLKNQSFAKS 428
Query: 289 LCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPF-EANTYQETYKRIS 342
+ GT +++ PEM E +DE VD+++ G+ E + P+ E + + YKR++
Sbjct: 429 VIGTPEFMAPEMYEEH-YDEAVDVYAFGMCMLEMASSEYPYSECSNAAQIYKRVT 590
>01966
Length = 1735
Score = 79.0 bits (193), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 42/135 (31%), Positives = 70/135 (51%), Gaps = 4/135 (2%)
Frame = -1
Query: 173 GVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEY--APLGTVYRELQKLSKFDE 230
GV RE+ + LRH NI+ L + R++L+ E+ L + + D
Sbjct: 1588 GVPSSAIREIAMLRELRHTNIVCLEDVIMEDERLFLVFEFLSMDLKMYIDKFPEGVVLDR 1409
Query: 231 QRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGW--SVHAPSSRRTT 288
+ +Y+ ++ +++CH +R++HRD+KP+NLL+ G +KIADFG + P T
Sbjct: 1408 RLVKSYVFQIVTGINFCHQRRIVHRDLKPQNLLINHTGAIKIADFGMARTFALPVRAYTH 1229
Query: 289 LCGTLDYLPPEMIEG 303
TL Y PE++ G
Sbjct: 1228 EVVTLWYRAPEILMG 1184
>19761
Length = 473
Score = 76.3 bits (186), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 40/142 (28%), Positives = 77/142 (54%), Gaps = 4/142 (2%)
Frame = -3
Query: 230 EQRTATYITELANALSYCHSKR--VIHRDIKPENLLLGSAGELKIADFGWS--VHAPSSR 285
E+ ++ + A+AL+Y H+ ++HRD+KP+N+ + G++++ D G + + P+
Sbjct: 426 ERLIVCWLMQTASALNYMHTHTPVILHRDLKPQNIYVTEKGDVRLGDLGLARKLTGPADF 247
Query: 286 RTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVE 345
T+ GT+ YL PE++ + ++ K D+WSLG + Y+ K E + + +
Sbjct: 246 ATSQVGTIMYLSPEILSQQPYNSKSDIWSLGCVFYDITGKKGSDEMGVMFLLVQVMGGRK 67
Query: 346 FTFPDFVTEGARDLISRLLKHN 367
PD ++ RD ISR+L +
Sbjct: 66 LPLPDHYSQEFRDTISRMLTKD 1
>19094
Length = 898
Score = 70.1 bits (170), Expect(2) = 6e-14, Method: Compositional matrix adjust.
Identities = 39/103 (37%), Positives = 57/103 (55%), Gaps = 2/103 (1%)
Frame = +1
Query: 230 EQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS--VHAPSSRRT 287
E+ AT + L Y HS+R IHRDIK N+LL + G K+ADFG + + ++R
Sbjct: 55 EREIATILYYTLKGL*YLHSRRKIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRN 234
Query: 288 TLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFE 330
T+ GT ++ PE+I+ +D D+WSLG+ E G E
Sbjct: 235 TVIGTPYWMAPEVIQEIGYDCVADIWSLGITALEMAEGNLHME 363
Score = 24.6 bits (52), Expect(2) = 6e-14, Method: Compositional matrix adjust.
Identities = 12/38 (31%), Positives = 19/38 (50%)
Frame = +3
Query: 346 FTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWI 383
F PD + D +S+ L NP R ++L+H +I
Sbjct: 417 FRQPDKWSTEFIDFVSKCLVKNPENRATAVDLLQHDFI 530
>26560
Length = 398
Score = 74.7 bits (182), Expect = 7e-14, Method: Composition-based stats.
Identities = 40/131 (30%), Positives = 67/131 (51%), Gaps = 1/131 (0%)
Frame = -1
Query: 218 VYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGW 277
++ L + F E+ Y E+ L + HS+ V++RD+KP N+LL G ++I+D G
Sbjct: 395 LHYHLSQHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGL 216
Query: 278 SVHAPSSRRTTLCGTLDYLPPE-MIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQE 336
+ R GT Y+ PE +++G+ +D D +S G + Y+ L G PF + +
Sbjct: 215 ACDFSKKRPHASVGTHGYMAPEVLMKGQSYDSSADWFSFGCMLYKLLKGHSPFR--QHNQ 42
Query: 337 TYKRISRVEFT 347
RI R+ T
Sbjct: 41 GQARIDRMTMT 9
>29581
Length = 1278
Score = 72.0 bits (175), Expect = 4e-13, Method: Compositional matrix adjust.
Identities = 63/235 (26%), Positives = 101/235 (42%), Gaps = 38/235 (16%)
Frame = -2
Query: 187 HLRHPNILRL----YGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELAN 242
+LRH NI++L G D+ ++L++EY + F E + + +L
Sbjct: 1187 NLRHQNIVQLQEVVVGKSLDS--LFLVMEYCEQDLASLLDNMPAPFSESQVKCIVLQLLK 1014
Query: 243 ALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVH--APSSRRTTLCGTLDYLPPEM 300
L Y H +IHRD+K NLL+ G +KIADFG + + P T TL Y PE+
Sbjct: 1013 GLRYLHEAFIIHRDLKVSNLLMTDKGCVKIADFGLARNYGKPQKPMTPKVVTLWYRAPEL 834
Query: 301 IEG-RMHDEKVDLWSLGVLCYEFLVGKPPFEANT-------------------------- 333
+ G + H +D+WS G + E L KP +
Sbjct: 833 LFGSKTHSTAIDMWSAGCILGELLGHKPLMPGRSDLQQIELIMELLGTPNDTIWPGFSQL 654
Query: 334 ---YQETYKR--ISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWI 383
Q T K+ + + TFP +++E L++ L ++P +R + LEH +
Sbjct: 653 PAFEQFTLKKQPYNNLRHTFP-WLSESGIRLLNGLFMYHPQKRATAEDCLEHSYF 492
>20152
Length = 445
Score = 68.9 bits (167), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 32/96 (33%), Positives = 50/96 (52%), Gaps = 1/96 (1%)
Frame = +1
Query: 298 PEMIEGRMHDE-KVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGA 356
PE++ G +D VD+WSLGV+ Y +VG+ PF+ ET I + P ++
Sbjct: 1 PEILLGDSYDAPAVDVWSLGVILYMLVVGEAPFQEANDSETLTMIMDCRYQIPPHISHKC 180
Query: 357 RDLISRLLKHNPSQRPMLREVLEHPWITANSSKPSN 392
+DLI ++L+ P R L +L HPW+ P+
Sbjct: 181 QDLIEKMLQREPVDRASLPHILAHPWLNDGDLTPTT 288
>27405
Length = 532
Score = 67.8 bits (164), Expect = 7e-12, Method: Compositional matrix adjust.
Identities = 47/175 (26%), Positives = 84/175 (48%), Gaps = 5/175 (2%)
Frame = -3
Query: 144 FGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLR----HPNILRLYGY 199
FG VY R+ + + A+K L K +++ G E E + S + P I+ +
Sbjct: 527 FGEVYGCRKADTGKMYAMKCLDKKRIKMKGGETLALNERIMLSLVSTGEGSPFIVCMTYA 348
Query: 200 FHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKP 259
F ++ IL+ G ++ L + F E+ Y E+ L + HS+ V++RD+KP
Sbjct: 347 FQTPEKLCFILDLMNGGDLHYHLSQHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKP 168
Query: 260 ENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPE-MIEGRMHDEKVDLW 313
N+LL G ++I+D G + + GT Y+ PE +++G+ +D D +
Sbjct: 167 ANILLDENGHVRISDLGLACDFSKKKPHASVGTHGYMAPEVLMKGQAYDSSADWF 3
>26711
Length = 405
Score = 65.9 bits (159), Expect = 3e-11, Method: Composition-based stats.
Identities = 39/132 (29%), Positives = 72/132 (54%), Gaps = 8/132 (6%)
Frame = -2
Query: 237 ITELANALSYCHSKRVIHRDIKPENLLLG--SAGELKIADFGWSVHAPSSRRTTLC-GTL 293
+ ++ + L + H++ V+H D+KP NLLL +++ DFG + + T L GT
Sbjct: 398 VKQVLDILQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARKLYPPQETFLNHGTP 219
Query: 294 DYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTF---PD 350
+ PE ++ + D+W +GVL Y L G+ PF+A++ E+ K+ +++F P
Sbjct: 218 GFTSPEALDVKPISTASDVWGVGVLAYILLSGQSPFQADSATESLKKTQTCDWSFDVCPS 39
Query: 351 F--VTEGARDLI 360
F +++ A+D I
Sbjct: 38 FSNMSQDAKDFI 3
>19301
Length = 712
Score = 65.1 bits (157), Expect = 5e-11, Method: Compositional matrix adjust.
Identities = 33/101 (32%), Positives = 56/101 (55%), Gaps = 2/101 (1%)
Frame = +2
Query: 180 REVEIQS--HLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYI 237
+E +I++ L HPNI+ G A +I+EY P G +Y L+ + +
Sbjct: 410 KETDIRNLRKLNHPNIISFKGVCTQAPCYCIIMEYCPYGQLYEVLRDGKEIPPALVLDWS 589
Query: 238 TELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS 278
++A+ ++Y HS ++IHRD+K N+L+ +KI+DFG S
Sbjct: 590 KQIASGMNYLHSHKIIHRDLKSPNVLVAKNDVVKISDFGTS 712
>38560
Length = 479
Score = 64.7 bits (156), Expect = 6e-11, Method: Compositional matrix adjust.
Identities = 33/111 (29%), Positives = 58/111 (52%), Gaps = 1/111 (0%)
Frame = -3
Query: 287 TTLCGTLDYLPPEMIEGRMH-DEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVE 345
TT CG+ Y PE+I G + + D+WS+GVL Y L G PF+ ++ + +
Sbjct: 411 TTCCGSPAYAAPELISGLEYLGSEADIWSMGVLLYALLCGYLPFDDEKXSHL*QKNQKRK 232
Query: 346 FTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQNK 396
P++++E L+ +L+ +PS R +R +L+H W+ + P +K
Sbjct: 231 DEVPEWLSEDTTKLLEGMLQTDPSHRITIRRLLDHHWLNQGFNVPVEWASK 79
>14477
Length = 493
Score = 63.9 bits (154), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 44/142 (30%), Positives = 73/142 (51%), Gaps = 2/142 (1%)
Frame = -1
Query: 139 LGKGKFGNVY--LAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRL 196
LG G FG+V + R + +A+KVL A L+ + V+ +L +E E+ + H +I+RL
Sbjct: 466 LGAGNFGSVMKGVCRLDDREIPVAIKVLKNADLDPS-VQSELIKEAEVMKKMDHMHIVRL 290
Query: 197 YGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRD 256
G T + L+LE A LG + + L K + +++ + Y + + +HRD
Sbjct: 289 IGLCEGET-MMLVLELAKLGPLNKFLPKNKHLPLWNILELMWQVSQGMEYLEANKFVHRD 113
Query: 257 IKPENLLLGSAGELKIADFGWS 278
+ N+LL KI+DFG S
Sbjct: 112 LAARNILLCDEHFAKISDFGMS 47
>04852
Length = 1462
Score = 63.9 bits (154), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 40/151 (26%), Positives = 75/151 (49%), Gaps = 5/151 (3%)
Frame = +1
Query: 235 TYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTL- 293
+Y ++A + + S++ IHRD+ N+L+ LKIADFG S ++ + G L
Sbjct: 337 SYAFQIARGMEFLASRKCIHRDLAARNVLVTEEHVLKIADFGLSRTGDYYKKRS-GGRLP 513
Query: 294 -DYLPPEMIEGRMHDEKVDLWSLGVLCYE-FLVGKPPFEANTYQETYKRISRVEFTF--P 349
++ PE + + K D+WS GV+ +E F +G P+ + +E Y ++ + P
Sbjct: 514 VKWMAPEALFDMRYTTKSDVWSFGVVLWEIFSLGGMPYASIPNEELYSKLLDDAYRMPRP 693
Query: 350 DFVTEGARDLISRLLKHNPSQRPMLREVLEH 380
+ + ++ R + PS RP +++ H
Sbjct: 694 ELASGNLYAIMERCWLNRPSDRPEFSQLVGH 786
>06358
Length = 1517
Score = 63.5 bits (153), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 65/273 (23%), Positives = 121/273 (44%), Gaps = 40/273 (14%)
Frame = +3
Query: 140 GKGKFGNVYLAREKQSK-----FILALKVLFK-AQLEKAGVEHQLRREVEIQSHLRHPNI 193
G G V+ A +K +K F+ K + + ++ ++ + LR V+ + LRHP I
Sbjct: 33 GPGLLWKVFAASKKSTKEEASVFVFEKKSVDRYSRRDREAIVEVLRVGVQQLTKLRHPKI 212
Query: 194 LRLYGYFHD-------------ATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITEL 240
L + + A+ ++ + + + TV +ELQ +D + + ++
Sbjct: 213 LAVINPLEESRETLAFATEPVFASLANVLGDLSSIXTVPKELQDYQLYDVE-IKHGLLQV 389
Query: 241 ANALSYCHSK-RVIHRDIKPENLLLGSAGELKIADFGWSVHA--PSSR---------RTT 288
AL + H+ +++HR++ PE ++L G K+A + + V + P S R+
Sbjct: 390 TEALGFLHNDAKMMHRNVCPEAIMLTKLGSWKLAGYEFCVRSSDPQSTDPSYPFYEWRSD 569
Query: 289 LCGT----LDYLPPEMIEGRMHDEKVDLWSLGVLCYE-FLVGKPPFEAN----TYQETYK 339
+ LD++ PE + D++SLG+L Y F GKP FE N ++ +
Sbjct: 570 IAPVTQPHLDFMAPEYVLTMQCGTGSDMFSLGLLVYSVFAKGKPLFECNGELSAFKSNAE 749
Query: 340 RISRVEFTFPDFVTEGARDLISRLLKHNPSQRP 372
+ + + V E RD + LL P+ RP
Sbjct: 750 ELRHMRVSLLGVVPEDLRDHVKLLLNIEPAVRP 848
>04138
Length = 800
Score = 63.5 bits (153), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 51/177 (28%), Positives = 72/177 (40%), Gaps = 40/177 (22%)
Frame = +1
Query: 244 LSYCHSKRVIHRDIKPENLLLGSAGELKIADFG----WSVHAPS-SRRTTLCGTLDYLPP 298
L Y H +++HRD+K N+L+ G LK+ADFG +SV+ +R T TL Y PP
Sbjct: 52 LYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRPP 231
Query: 299 EMIEG-RMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGAR 357
E++ G R + +D W G + E P + T Q I+++ + V G
Sbjct: 232 ELLLGDRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQNQLTLITQLCGSITPEVWPGVT 411
Query: 358 ----------------------------------DLISRLLKHNPSQRPMLREVLEH 380
DL RLLK +PSQR E L H
Sbjct: 412 QLSMYHQIKGALAAGRKNIIRDRFARILKDPYGLDLFERLLKMDPSQRISADEALNH 582
>21808
Length = 1011
Score = 63.2 bits (152), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 43/166 (25%), Positives = 73/166 (43%), Gaps = 5/166 (3%)
Frame = +1
Query: 181 EVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYI-TE 239
E +I LRHP +++LY +++I E G++ LQ + + I +
Sbjct: 82 EAQIMKKLRHPKLIQLYAVCTQDDPIFIITELMKNGSLLEFLQGKGRVLKLPALIDIGAQ 261
Query: 240 LANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGT---LDYL 296
+A ++Y S+ IHRD+ N+L+ +KIADFG + G + +
Sbjct: 262 IACGMAYLESQNYIHRDLAARNILVSDNNTVKIADFGLARVIKEDEYEARVGARFPIKWT 441
Query: 297 PPEMIEGRMHDEKVDLWSLGVLCYEFLV-GKPPFEANTYQETYKRI 341
PE K D+WS G+L E + G+ P+ T E ++
Sbjct: 442 APEAANYNRFTIKSDVWSFGILLTETVTYGRVPYPGMTNAEVLHQV 579
>00715
Length = 1788
Score = 61.6 bits (148), Expect = 5e-10, Method: Compositional matrix adjust.
Identities = 47/177 (26%), Positives = 76/177 (42%), Gaps = 33/177 (18%)
Frame = +1
Query: 188 LRHPNILRLYGY-----FHDATRVYLILEYAP---LGTVYRELQKLSKFDEQRTATYITE 239
LRH N++ + G F D +L +EY L T+ + Q+ D + +
Sbjct: 97 LRHVNVVSILGATSLHRFEDGA--WLAMEYVGPLNLQTILNDHQQ--DIDSSMRLSLALQ 264
Query: 240 LANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVH------------------- 280
+A L Y HS ++H D+KP N LL +L+IADFG H
Sbjct: 265 MARGLHYLHSINIVHLDLKPANCLLTRDLKLRIADFG-CCHQLTPTGLDMGEREGGMAGN 441
Query: 281 ------APSSRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEA 331
+ + L GTL Y PE+++G + D++SLG+ ++ + P+E
Sbjct: 442 ELELTPVQGAWKNELAGTLAYRAPELLKGLQPSVRSDVYSLGITLWQMCTRQGPYEG 612
>14116
Length = 1017
Score = 61.2 bits (147), Expect = 6e-10, Method: Compositional matrix adjust.
Identities = 56/217 (25%), Positives = 96/217 (44%), Gaps = 24/217 (11%)
Frame = -1
Query: 131 EDFEIGRPLGKGKFGNV---YLAR-EKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQS 186
E +G +GKG FG V +L E++ ++A+K L RE+E+QS
Sbjct: 636 EFLTMGEEIGKGNFGCVKRGFLTLPEQKGDILVAVKTLHNNN----------PREIELQS 487
Query: 187 HLR---------HPNILRLYGY---FHDATRVYL-ILEYAPLGTVYRELQKLSKFDEQRT 233
L+ H N+L L G D V L +++ L T R+ Q +
Sbjct: 486 FLQEALIMKDFHHSNVLTLIGICLNLDDMPLVVLPFMKHGDLLTYIRDDQHQPTIKD--L 313
Query: 234 ATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS-------VHAPSSRR 286
Y ++A + Y + +HRD+ N +L +K+ADFG + ++ +++
Sbjct: 312 IMYGVDIARGMDYLAGLKFVHRDLAARNCMLDEDFHVKVADFGLARDIYEKEYYSSENKK 133
Query: 287 TTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFL 323
L + ++ E +E +D K D+WS GV+ +E L
Sbjct: 132 AKL--PVKWMALESLEKGNYDSKTDVWSYGVVLWELL 28
>28157
Length = 400
Score = 61.2 bits (147), Expect = 8e-10, Method: Compositional matrix adjust.
Identities = 39/104 (37%), Positives = 57/104 (54%), Gaps = 7/104 (6%)
Frame = +3
Query: 180 REVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLS---KFDEQRTATY 236
+E++ S + HPNI+ LYG D V L++EYA G++Y L ++ +
Sbjct: 57 QELKQLSRVSHPNIVCLYGACRDHP-VCLVMEYAEGGSLYNVLHGSGPQPQYTAAHAMNW 233
Query: 237 ITELANALSYCHS---KRVIHRDIKPENLLLGSAG-ELKIADFG 276
+ + A + Y H K +IHRD+KP NLLL G +LKI DFG
Sbjct: 234 LLQCALGVEYLHGMKPKALIHRDLKPPNLLLIQCGTKLKICDFG 365
>12672
Length = 773
Score = 60.8 bits (146), Expect = 9e-10, Method: Compositional matrix adjust.
Identities = 45/161 (27%), Positives = 69/161 (42%), Gaps = 24/161 (14%)
Frame = +3
Query: 241 ANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTT------LCGTLD 294
A+ + Y + +HRDIK N+LL S K+ DF V APS T + GT
Sbjct: 21 ASGIQYLNDNGHVHRDIKTANILLDSEYTAKVGDFATVVSAPSGEGKTVQNASVVIGTAA 200
Query: 295 YLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTY------------------QE 336
YL PE I + K+D +S GV+ E + G A Y +E
Sbjct: 201 YLAPEAIHFDVS-TKLDSYSFGVVLLEVITG---LVAQDYSREERTLSSHIMENVEEPEE 368
Query: 337 TYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREV 377
+ + + T+PD + D+ R L + QRP ++++
Sbjct: 369 IHDFVDQSAGTWPDGAVDKLYDISMRCLNLSKKQRPNVKDI 491
>07940
Length = 1336
Score = 60.8 bits (146), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 36/100 (36%), Positives = 54/100 (54%), Gaps = 5/100 (5%)
Frame = -3
Query: 235 TYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS--VHAPSSRRTTLCGT 292
+Y ++A + Y SK+ IHRD+ N+L+ LKIADFG + + R T G
Sbjct: 335 SYAYQVARGMEYLASKQCIHRDLAARNVLVAEEYVLKIADFGLTRNLQQFDYYRKTTDGR 156
Query: 293 L--DYLPPEMIEGRMHDEKVDLWSLGVLCYE-FLVGKPPF 329
L ++ PE + R + K D+WS GVL +E F +G P+
Sbjct: 155 LPVKWMAPEALFDRKYTSKSDVWSYGVLLWEIFTLGGNPY 36
Score = 34.3 bits (77), Expect = 0.088, Method: Compositional matrix adjust.
Identities = 28/95 (29%), Positives = 49/95 (51%), Gaps = 7/95 (7%)
Frame = -3
Query: 131 EDFEIGRPLGKGKFGNVYLAREKQSKF------ILALKVLFKAQLEKAGVEHQLRREVEI 184
E +G LG+G FG V + E F +A+K+L + ++ ++ L RE+E+
Sbjct: 842 ERLVLGDRLGEGAFGLV-MKGEAMGIFKDNNSVTVAVKMLKEDATDREMMD--LIREMEM 672
Query: 185 QSHL-RHPNILRLYGYFHDATRVYLILEYAPLGTV 218
+ +H NI+ L G +Y+I+E+AP G +
Sbjct: 671 MKVIGKHKNIINLLGCCTQRGALYVIVEFAPHGNL 567
>03508
Length = 1463
Score = 60.8 bits (146), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 31/109 (28%), Positives = 57/109 (52%), Gaps = 3/109 (2%)
Frame = +1
Query: 223 QKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAG-ELKIADFGWS-VH 280
Q F + Y+ EL AL +CHS ++HRD+KP N+++ +L++ D+G + +
Sbjct: 847 QLYQTFTDYDIRFYLYELMKALDFCHSMGIMHRDVKPHNVMIDHENKKLRLIDWGLAEFY 1026
Query: 281 APSSRRTTLCGTLDYLPPE-MIEGRMHDEKVDLWSLGVLCYEFLVGKPP 328
P + + PE +++ +M+D +D+WSLG + + K P
Sbjct: 1027HPGMEYNVRVASRYFKGPELLLDYQMYDYSLDMWSLGCMFASMIFRKEP 1173
>26009
Length = 886
Score = 40.8 bits (94), Expect(2) = 3e-09, Method: Compositional matrix adjust.
Identities = 17/49 (34%), Positives = 30/49 (61%)
Frame = +3
Query: 216 GTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLL 264
GT ++ + + + +L +AL + HSK+++HRDIKPEN+L+
Sbjct: 666 GTCLTPSRRNKACGSREAKSVMKQLVSALDFMHSKQLVHRDIKPENVLI 812
Score = 38.1 bits (87), Expect(2) = 3e-09, Method: Compositional matrix adjust.
Identities = 26/91 (28%), Positives = 47/91 (51%), Gaps = 2/91 (2%)
Frame = +2
Query: 131 EDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLR- 189
E +++ + LG+G +G V LAR + + +ALK+L K+ + + +RE ++ L
Sbjct: 416 EHYDVCKELGRGTYGKVVLARCRHTGTQVALKLLPKSCTKL----REFQREFQLSYFLSP 583
Query: 190 HPNILRLYGY-FHDATRVYLILEYAPLGTVY 219
H NI+ Y F + E+A LG ++
Sbjct: 584 HANIIDTYNVAFQTRSSYVFAQEHAVLGDLF 676
>12786
Length = 460
Score = 58.9 bits (141), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 37/127 (29%), Positives = 54/127 (42%), Gaps = 24/127 (18%)
Frame = -3
Query: 228 FDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRT 287
D Y E+ A+ H++ VIH D+KP N +L AG LK+ DFG + + +
Sbjct: 419 LDRMMIKFYWREMLRAVKALHNEGVIHSDLKPANFML-VAGNLKLIDFGIANTLQQDKTS 243
Query: 288 TL----CGTLDYLPPEMIEGRMHDE--------------------KVDLWSLGVLCYEFL 323
L GT Y+ PE I D + D+WSLG + Y +
Sbjct: 242 VLKDSRVGTPSYMSPEAIMAACDDSADDSMEEDGHRTKPKYKVGVRSDVWSLGCILYNMV 63
Query: 324 VGKPPFE 330
G+ PF+
Sbjct: 62 YGRTPFQ 42
>18663
Length = 600
Score = 57.8 bits (138), Expect = 7e-09, Method: Compositional matrix adjust.
Identities = 32/112 (28%), Positives = 52/112 (46%), Gaps = 15/112 (13%)
Frame = +2
Query: 287 TTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEA---------NTYQET 337
+T CGT +Y+ PE++ G + VD W+LGVL YE L G+ PF+ NT
Sbjct: 2 STFCGTPNYIAPEILRGEDYGFSVDWWALGVLLYEMLAGRSPFDIAGASENPDQNTEDYL 181
Query: 338 YKRISRVEFTFPDFVTEGARDLISRLLKHNPSQR------PMLREVLEHPWI 383
++ I P ++ A ++ L NP+ R +++ HP+
Sbjct: 182 FQVILEKTIRIPRSLSVKAASVLKGFLNKNPADRLGCHRESAFMDIVNHPFF 337
>28638
Length = 1458
Score = 55.8 bits (133), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 41/132 (31%), Positives = 60/132 (45%), Gaps = 5/132 (3%)
Frame = -1
Query: 203 ATRVYLILEYAP-LGTVYRELQKLSKFDEQRTATYITELANALSYCHS--KRVIHRDIKP 259
AT L +P + T Q L T + +L AL + + +IH D+KP
Sbjct: 924 ATTCVWCLSCSPTISTTCYATQTLEGVSLNLTRKFAQQLCTALLFLATPEMNIIHCDLKP 745
Query: 260 ENLLLGSA--GELKIADFGWSVHAPSSRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGV 317
EN+LL + +KI DFG S R + Y PE++ G +D +D+WSLG
Sbjct: 744 ENILLCNPKRSAIKIVDFGSSCQL-GQRIYQYIQSRFYRSPEVLLGVPYDLAIDMWSLGC 568
Query: 318 LCYEFLVGKPPF 329
+ E G+PP
Sbjct: 567 ILVEMHTGEPPL 532
>02638
Length = 1490
Score = 53.1 bits (126), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 27/104 (25%), Positives = 52/104 (50%), Gaps = 5/104 (4%)
Frame = +1
Query: 289 LCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFT- 347
L GT+ ++ PE++ G + D+WS+G + E +PP+ ++ I ++ +
Sbjct: 16 LLGTIAFMAPEVLRGESYGRACDVWSVGCVMIEMCTCRPPWNSHDISNHLALIFKIASSV 195
Query: 348 ----FPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANS 387
P+ ++ RDL+ R L+ + RP +++L HP T S
Sbjct: 196 DPPPIPENMSPPVRDLMLRCLEQDSDFRPSAKDLLMHPLFTKYS 327
>11185
Length = 473
Score = 52.4 bits (124), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 30/110 (27%), Positives = 48/110 (43%), Gaps = 24/110 (21%)
Frame = +1
Query: 240 LANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFG----------------------W 277
L L Y HS ++ D++P +LL ++G LK ADFG W
Sbjct: 28 LVTGLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQW 207
Query: 278 SVHAPSS--RRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVG 325
++ + ++ G+ Y+ PE+ +G DLW+LG + YE G
Sbjct: 208 NIQSAEEMMKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSG 357
>25019
Length = 730
Score = 52.4 bits (124), Expect = 4e-07, Method: Compositional matrix adjust.
Identities = 25/59 (42%), Positives = 35/59 (59%), Gaps = 2/59 (3%)
Frame = +3
Query: 260 ENLLLGSAGELKIADFGWSVHAPSSRRTT--LCGTLDYLPPEMIEGRMHDEKVDLWSLG 316
EN+LL G +K+ DFG A + R T CGT++Y+ PE++ H + VD WSLG
Sbjct: 261 ENVLLDKDGHVKLTDFGLCKEAITGTRVTHTFCGTIEYMAPEILTRTGHGKAVDWWSLG 437
>29590
Length = 320
Score = 38.9 bits (89), Expect(2) = 1e-06, Method: Composition-based stats.
Identities = 17/41 (41%), Positives = 24/41 (58%)
Frame = +3
Query: 289 LCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPF 329
+ GT DY+ PE+++ + D+WSLGVL Y L PF
Sbjct: 54 IIGTPDYVAPEVLDYEPLSIQTDMWSLGVLSYVMLTACSPF 176
Score = 31.2 bits (69), Expect(2) = 1e-06, Method: Composition-based stats.
Identities = 16/41 (39%), Positives = 24/41 (58%), Gaps = 4/41 (9%)
Frame = +2
Query: 335 QETYKRISRVEFTFPD----FVTEGARDLISRLLKHNPSQR 371
QET+ IS+V+ FPD ++ A+D I +LL +P R
Sbjct: 191 QETFCNISQVKLDFPDDLFSHISPHAKDFIKKLLVKDPRHR 313
>27274
Length = 396
Score = 49.7 bits (117), Expect = 2e-06, Method: Composition-based stats.
Identities = 30/97 (30%), Positives = 45/97 (46%), Gaps = 12/97 (12%)
Frame = -1
Query: 299 EMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEAN------------TYQETYKRISRVEF 346
E++ G+ H VD+WSLG+L +E L G PFE Y + + SR
Sbjct: 375 ELLRGQQHGPTVDMWSLGILLHELLSGHVPFEPERGSRQMARNMMAVYAQIIRGSSRDVC 196
Query: 347 TFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWI 383
T GA D + RL++ ++R ++ HPWI
Sbjct: 195 DGLALSTHGA-DFLRRLVQLEDTKRLTSQQAFSHPWI 88
>31120
Length = 439
Score = 48.9 bits (115), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 33/99 (33%), Positives = 53/99 (53%), Gaps = 6/99 (6%)
Frame = +1
Query: 299 EMIEGRMHDEKV-DLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTF----PDFVT 353
E++ G +D K+ D WSLGV+ + L GK PF+ + + + +++F D V+
Sbjct: 1 EVVCGVPYDPKMADAWSLGVILFIMLNGKMPFDDSNLNKLLEDQRSKKYSFRRKLQDLVS 180
Query: 354 EGARDLISRLLKHNPSQRPMLREVLEHPWI-TANSSKPS 391
AR +S LL+ N + R L EVL W+ T + +PS
Sbjct: 181 PNARSTVSVLLEPNSAMRWDLNEVLNCQWLQTIDEPRPS 297
>37602
Length = 804
Score = 48.5 bits (114), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 32/99 (32%), Positives = 46/99 (46%), Gaps = 3/99 (3%)
Frame = -1
Query: 189 RHPNILRLYGYFHDATR---VYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALS 245
R NI GYF R +++ +EY G++ E + A E L
Sbjct: 354 RIVNIQTFVGYFDSYLRREKLWIAMEYCGGGSMQDIYHVTGPLTEPQIAFVCRETLKGLH 175
Query: 246 YCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSS 284
Y H + +HRDIK N+LL G++K+ADF W V + S
Sbjct: 174 YLHRRGKMHRDIKGANILLTEEGDVKLADF-WRVSSNHS 61
>07833
Length = 1504
Score = 48.1 bits (113), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 45/213 (21%), Positives = 88/213 (41%), Gaps = 21/213 (9%)
Frame = -3
Query: 188 LRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKF--DEQRTATYITELANALS 245
HPN+L + + + LI ++ P G++Y L S D+ ++ + ++A +
Sbjct: 1448 FNHPNVLPVLACCNQPPNLVLISQFMPFGSLYNTLHGESGIVVDQNQSLRFAMDIARGME 1269
Query: 246 YCHSKRVIHRDIKPE--NLLLGS---------AGELKIADFGWSVHAPSSRRTTLCGTLD 294
+ HS ++P N LL S + +AD+ +S H +
Sbjct: 1268 FLHS-------MEPTIPNFLLTSKHVMIDEDLTARINMADYCFSFHEKGKVYSP-----A 1125
Query: 295 YLPPEMIEGRMHD---EKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISR--VEFTFP 349
++ PE ++ R D D+WS +L +E + PF + E +++ + + P
Sbjct: 1124 WMAPEALQRRPDDINTRAADMWSFAILMWELETREVPFAELSSMEVGMKVALEGLRISIP 945
Query: 350 DFVTEGARDLISRLLKHNPSQRP---MLREVLE 379
++ LI + P +RP M+ +LE
Sbjct: 944 PGISLHMSRLIKICMNEEPGKRPRFDMIIPILE 846
>32000
Length = 644
Score = 48.1 bits (113), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 39/148 (26%), Positives = 63/148 (42%), Gaps = 31/148 (20%)
Frame = -1
Query: 267 AGELKIADFGWS--VHAPSSRRTTLCGTLDYLPPEMIEG-RMHDEKVDLWSLGVLCYEFL 323
++KIADFG + P T TL Y PE++ G R + VD+WSLG + E +
Sbjct: 581 TAKMKIADFGLARVFGLPVRTYTHEVITLWYRAPEILLGCRFYSVPVDIWSLGCIFVEMM 402
Query: 324 VGKPPFEANTYQETYKRISRVEFT-----------FPDF-----------------VTEG 355
+ F ++ + RI R T PD+ +++
Sbjct: 401 TRRALFPGDSEIDQLYRIFRTLGTPDEKVWPGVSKLPDYKPTFPKWPLKNLETVVSLSKV 222
Query: 356 ARDLISRLLKHNPSQRPMLREVLEHPWI 383
DL+ R+L +NP++R R + HP+
Sbjct: 221 GLDLLKRMLTYNPNRRISARSAMRHPYF 138
>07291
Length = 833
Score = 47.8 bits (112), Expect = 8e-06, Method: Compositional matrix adjust.
Identities = 25/97 (25%), Positives = 50/97 (51%), Gaps = 6/97 (6%)
Frame = +1
Query: 239 ELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHA-PSSRRTT----LCGTL 293
++A+ ++Y +V+HR++ N ++ G L+++D+G + P S T +
Sbjct: 73 QIADGMAYLQEVKVVHRNLAARNCIVTEDGRLQLSDYGVTGSLFPQSYYTADDSPARDLV 252
Query: 294 DYLPPEMIEGRMHDEKVDLWSLGVLCYEFLV-GKPPF 329
++ PE I+ K D+W+ GV+ +E L G P+
Sbjct: 253 KWMAPETIDNFHFSSKSDVWAFGVVLWELLTRGITPY 363
>01106
Length = 878
Score = 46.6 bits (109), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 46/147 (31%), Positives = 70/147 (47%), Gaps = 15/147 (10%)
Frame = +3
Query: 133 FEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQ--LEKAGVEHQLRREVEIQSHLRH 190
+ + R LG G F V+L + K +ALKV+ AQ E A E +L + V +S +
Sbjct: 324 YHVIRKLGWGHFSTVWLCWDLTCKRFVALKVVKSAQHYTETALDEVKLLKCVR-ESDVAD 500
Query: 191 PNILRLYGYFHD-------ATRVYLILEYAPLGTVYRELQKLSKFDEQRTATY-----IT 238
P + D T V ++ E LG Y L+ + + + Q + I
Sbjct: 501 PARAKCVQLLDDFKISGVNGTHVAMVFEV--LG--YNLLKLIIRSNYQGIPIHNVKLIIR 668
Query: 239 ELANALSYCHSK-RVIHRDIKPENLLL 264
++ LSY H+K R+IH DIKPEN+L+
Sbjct: 669 QVLEGLSYMHAKCRIIHTDIKPENILI 749
>18481
Length = 437
Score = 44.7 bits (104), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 38/119 (31%), Positives = 57/119 (47%), Gaps = 7/119 (5%)
Frame = -1
Query: 167 AQLEKAGVEHQL-RREVEIQSHL-RHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQK 224
++E V+HQL E ++ + RHP + +Y Y + L++E LG EL
Sbjct: 395 VKIEAIDVKHQLLHYEAKVYEQIGRHPGLPTMYHYGTEKHFNALVME--LLGPSLEELFV 222
Query: 225 LSK--FDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLG---SAGELKIADFGWS 278
+ K F + +L + L + H K IHRD+KP+N L+G L I DFG S
Sbjct: 221 ICKRRFTLKTILMVSDQLLSRLEFIHQKCFIHRDLKPDNFLMGLGRHCHRLYIIDFGLS 45
>32957
Length = 645
Score = 44.7 bits (104), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 20/60 (33%), Positives = 32/60 (53%)
Frame = +3
Query: 275 FGWSVHAPSSRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTY 334
F V R T CGT +Y+ PE+ E + + ++VD W LG+L +E L + ++ Y
Sbjct: 3 FALCVEKSGGRTRTFCGTREYMAPEVHERKEYGKEVDWWGLGILLHELLAAQIKKHSSCY 182
>31489
Length = 329
Score = 43.9 bits (102), Expect = 1e-04, Method: Composition-based stats.
Identities = 23/88 (26%), Positives = 43/88 (48%), Gaps = 6/88 (6%)
Frame = +3
Query: 182 VEIQSHLRHPNI------LRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTAT 235
++I H +H NI L+ +HD ++++ + ++R + E+
Sbjct: 3 IKILKHFKHDNIISIREILKPKDSYHDFKDIHVVFDLME-SDLHRIIYSDQPLTEEHIRY 179
Query: 236 YITELANALSYCHSKRVIHRDIKPENLL 263
++ ++ L Y HS V+HRD+KP NLL
Sbjct: 180 FLYQILRGLKYIHSANVVHRDLKPSNLL 263
>16708
Length = 1397
Score = 43.9 bits (102), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 64/266 (24%), Positives = 100/266 (37%), Gaps = 33/266 (12%)
Frame = -1
Query: 139 LGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNIL-RLY 197
LGKG FG VY AR L KA L+ + + H EVE + L +++
Sbjct: 1379 LGKGVFGKVYEAR--------LLSTHEKAALKTSILCHHSLDEVEALGRIEGGFYLAQMF 1224
Query: 198 GY------FHDATRVYLILEYAPLGTVYRELQK----LSKFDEQRTATYITELANALSYC 247
G F + E PL VY + + + + AL +
Sbjct: 1223 GAWVTCLPFPKMNILLHFYEMGPLCNVYAHYKNKEMPIRWSNPAMVCCIAGQXVCALEHI 1044
Query: 248 HSKRVIHRDIKPENLLLGSAGELKIADFG----WSVH-APSSRRTTLCG---TLDYLPPE 299
H V+H D+K +N+L+ + G K+ D+G + V+ AP+ ++ C T PP
Sbjct: 1043 HELGVVHMDVKADNVLVDAHGNCKLTDYGIAQLYKVYPAPTETHSSGCTNKRTFYTRPPA 864
Query: 300 -MIEGRMHDEKVD------------LWSL-GVLCYEFLVGKPPFEANTYQETYKRISRVE 345
M E+ D LW+L G + V +PP + + R E
Sbjct: 863 TMTPSERFSEEGDGIGTDYFRLGQMLWTLTGAVLLHVWVSRPPKLPD-----WCRTPESE 699
Query: 346 FTFPDFVTEGARDLISRLLKHNPSQR 371
+ G D I +L +P+ R
Sbjct: 698 LS-------GMSDFIEKLCHGDPNMR 642
>17253
Length = 483
Score = 43.9 bits (102), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 27/112 (24%), Positives = 53/112 (47%), Gaps = 13/112 (11%)
Frame = -1
Query: 180 REVEIQSHL-RHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQK--------LSKFDE 230
RE+ I L RHPN++ G + +++E+ G + L+K L+
Sbjct: 402 RELSIMRKLPRHPNVVSFMGCCTMSDPALILMEFCCHGDLLSFLRKRRPDRTVFLTSTAN 223
Query: 231 QRTA----TYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS 278
TA ++ +A +++ + +++HRD+ N+L+ K++DFG S
Sbjct: 222 DLTARDFFSFALHVARGMAHVANNKIVHRDVAARNVLISERNVCKVSDFGLS 67
>20640
Length = 1492
Score = 43.5 bits (101), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 38/144 (26%), Positives = 65/144 (45%), Gaps = 5/144 (3%)
Frame = +1
Query: 253 IHRDIKPENLLLGSAGELKIADFGW--SVHAPSSRRTTLCGT--LDYLPPEMIEGRMHDE 308
+HRD+ N L+G +KI+DFG SVH+ R + + ++P E I
Sbjct: 10 VHRDLATRNCLVGHDLVVKISDFGLARSVHSVDYYRGSEHDAIPIRWMPLEAILYNKFST 189
Query: 309 KVDLWSLGVLCYE-FLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHN 367
+ D+WS GV+ +E F P+ T++E + FV EG ++L
Sbjct: 190 QSDVWSFGVVLWEIFAFALQPYYGLTHEEVVR-----------FVKEG------KVLACP 318
Query: 368 PSQRPMLREVLEHPWITANSSKPS 391
P + E+++ W +++PS
Sbjct: 319 ERTPPPMYELMKQCWHRRPATRPS 390
>07836
Length = 1478
Score = 42.7 bits (99), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 49/195 (25%), Positives = 85/195 (43%), Gaps = 31/195 (15%)
Frame = -1
Query: 159 LALKVLFKAQLEKAGVEHQLRREVEIQSH--LRHPNILRLYGY----FHDATRVYLILEY 212
+A+K+ F + E RE E+ LRH NIL T+++LI +Y
Sbjct: 1469 VAVKIFFTTE------EASWFRETELYQTVLLRHENILGFIAADIKGTGSWTQLFLITDY 1308
Query: 213 APLGTVYRELQKLSK-FDEQRTATYITELANALSYCHSK--------RVIHRDIKPENLL 263
G+++ L LS+ D L++ H + + HRDIK +N+L
Sbjct: 1307 HENGSLHDYL--LSRVLDSSEMLALAHSAICGLAHLHIEIFGTRGKPAIAHRDIKSKNIL 1134
Query: 264 LGSAGELKIADFGWSVH----------APSSRRTTLCGTLDYLPPEMIEGRMHD------ 307
+ G IAD G +V AP+ R+ GT Y+ PE++E ++
Sbjct: 1133 VKKNGTCCIADLGLAVRYISESNEVDVAPNPRQ----GTKRYMAPEVLEMLLNVKNFDAF 966
Query: 308 EKVDLWSLGVLCYEF 322
++ D+++ G++ +E
Sbjct: 965 KQADMYAFGLVMWEI 921
>20559
Length = 430
Score = 39.7 bits (91), Expect(2) = 3e-04, Method: Compositional matrix adjust.
Identities = 22/81 (27%), Positives = 45/81 (55%)
Frame = -2
Query: 130 LEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLR 189
++ +E +G+G +G V+ A+ +++ I+ALK + + + GV RE+ + L+
Sbjct: 378 MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRV-RLDDDDEGVPSSALREICLLKELK 202
Query: 190 HPNILRLYGYFHDATRVYLIL 210
H NI+RL+ H ++ L+
Sbjct: 201 HRNIVRLHDVLHSERKLTLVF 139
Score = 21.9 bits (45), Expect(2) = 3e-04, Method: Compositional matrix adjust.
Identities = 7/12 (58%), Positives = 9/12 (75%)
Frame = -1
Query: 244 LSYCHSKRVIHR 255
L +CHS V+HR
Sbjct: 37 LVFCHSNNVLHR 2
>17300
Length = 480
Score = 42.0 bits (97), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 29/98 (29%), Positives = 46/98 (46%), Gaps = 7/98 (7%)
Frame = +1
Query: 253 IHRDIKPENLLLGSAGELKIADFGWSVHAPSSRR----TTLCGTL--DYLPPEMIEGRMH 306
+HRD+ N+L+ K+ADFG S S TT G + + PE I R
Sbjct: 40 VHRDLAARNILVNEILVCKVADFGLSREIESDTTEGAYTTKGGKIPVRWTAPEAIAYRKF 219
Query: 307 DEKVDLWSLGVLCYEFL-VGKPPFEANTYQETYKRISR 343
D+WS GV+ +E + G+ P+ + Q+ K + +
Sbjct: 220 TSASDVWSFGVVMWEVMSYGERPYWNWSNQDVIKAVEK 333
>11404
Length = 563
Score = 40.8 bits (94), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 42/150 (28%), Positives = 71/150 (47%), Gaps = 12/150 (8%)
Frame = +1
Query: 127 QWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKV-------LFKAQLEKAGVEHQLR 179
+WA + +EI +GKG FG V A + +A+K+ L +AQ+E +E R
Sbjct: 130 KWA-DRYEIDSLIGKGSFGQVVKAYDHTDNEQVAIKIIKNKKPFLNQAQIEVKLLEMMNR 306
Query: 180 REVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKF---DEQRTATY 236
+ + + + I+RL +F R +L L + L +L + + F T +
Sbjct: 307 HDTDNKYY-----IVRLKRHF--MFRSHLCLVFELLSYNLYDLLRNTNFRGVSLNLTRKF 465
Query: 237 ITELANALSYCHS--KRVIHRDIKPENLLL 264
+L AL + + +IH D+KPEN+LL
Sbjct: 466 AQQLCTALLFLATPEMSIIHCDLKPENILL 555
>21210
Length = 518
Score = 40.4 bits (93), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 27/106 (25%), Positives = 49/106 (46%), Gaps = 13/106 (12%)
Frame = +3
Query: 291 GTLDYLPPEMIEGRM----HDEKVDLWSLGVLCYEFLVGKPPFE--ANTYQETYKRISRV 344
G Y+ PE I+ R +D + D+WSLG+ E G+ P+ + + + + + V
Sbjct: 6 GCRPYMAPERIDPRASSHGYDVRSDVWSLGITLMELATGRFPYRKWVSIFDQLQQVVRGV 185
Query: 345 EFTFP-------DFVTEGARDLISRLLKHNPSQRPMLREVLEHPWI 383
P DFV + +++ L + QRP ++L HP++
Sbjct: 186 APCLPHDGAFSHDFV-----NFVNKCLTKDEKQRPKYNKLLAHPFV 308
>21418
Length = 831
Score = 39.7 bits (91), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 20/56 (35%), Positives = 32/56 (57%), Gaps = 4/56 (7%)
Frame = +2
Query: 339 KRISRVEFTFPD----FVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKP 390
KRI ++ FPD V++ A+DLI +L +PS+R + +VL + WI + P
Sbjct: 8 KRIRSGQYDFPDPEWTNVSQAAKDLIKGMLNVDPSKRLCIEDVLRNKWIAQYDAVP 175
>20160
Length = 1277
Score = 38.5 bits (88), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 15/33 (45%), Positives = 24/33 (72%)
Frame = +2
Query: 354 EGARDLISRLLKHNPSQRPMLREVLEHPWITAN 386
E A DLI+R + +PS RP+L ++L+H W+T +
Sbjct: 332 EDAADLINRCIALDPSTRPVLADILKHKWMTKD 430
>00638
Length = 1595
Score = 38.1 bits (87), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 15/37 (40%), Positives = 21/37 (56%)
Frame = +2
Query: 223 QKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKP 259
Q F + Y+ EL AL +CHS ++HRD+KP
Sbjct: 392 QLYQTFTDYDIRFYLYELMKALDFCHSMGIMHRDVKP 502
>31789
Length = 676
Score = 36.6 bits (83), Expect = 0.018, Method: Compositional matrix adjust.
Identities = 27/103 (26%), Positives = 45/103 (43%), Gaps = 5/103 (4%)
Frame = +2
Query: 132 DFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHP 191
D EIGR G F VY + + +A L + K + + E E+ L+HP
Sbjct: 335 DVEIGR----GSFKTVYKGLDTELGVAVAWCELQDKKWNKT-ERQRFKEEAEMLKELQHP 499
Query: 192 NILRLYGYFHDATR-----VYLILEYAPLGTVYRELQKLSKFD 229
NI+R + Y+ + + L+ E GT+ L++ K +
Sbjct: 500 NIVRFFDYWEEHNHRNRKVIILVTELMTSGTLKTYLKRFKKIN 628
>36002
Length = 253
Score = 36.2 bits (82), Expect = 0.023, Method: Compositional matrix adjust.
Identities = 21/66 (31%), Positives = 31/66 (46%), Gaps = 5/66 (7%)
Frame = +1
Query: 324 VGKPPFEANTYQET-YKRISRVEFTFPDF----VTEGARDLISRLLKHNPSQRPMLREVL 378
V +P QE + RI + FP ++ A+DLI LL P +R +VL
Sbjct: 16 VAEPGEACQDCQELLFNRIQDGNYFFPSMEWSAISSSAKDLIRHLLVREPRKRYSAADVL 195
Query: 379 EHPWIT 384
+HPW+
Sbjct: 196 KHPWVC 213
>37063
Length = 455
Score = 35.4 bits (80), Expect = 0.043, Method: Compositional matrix adjust.
Identities = 23/77 (29%), Positives = 41/77 (53%), Gaps = 15/77 (19%)
Frame = -2
Query: 257 IKPENLLLGSAGE---LKIADF----GWSVHAPSSRRTTL---CGTLDYLPPEMIEGRM- 305
+KPEN+L E LKI DF G + ++ L G+ +Y+ PE+++ +
Sbjct: 454 LKPENILCEHLDEVVPLKICDFDLASGINCDGDGTKTPELLTPVGSAEYMAPEVVDAWVG 275
Query: 306 ----HDEKVDLWSLGVL 318
+D++ D+WSLG++
Sbjct: 274 ESFSYDKRCDMWSLGII 224
>20655
Length = 1181
Score = 34.7 bits (78), Expect = 0.068, Method: Compositional matrix adjust.
Identities = 17/56 (30%), Positives = 31/56 (55%), Gaps = 4/56 (7%)
Frame = +2
Query: 339 KRISRVEFTFP----DFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKP 390
KRI ++ FP V++ A+DLI +L +P +R +++V+ W+ N+ P
Sbjct: 8 KRIRNGQYEFPKPEWSRVSQDAKDLIRGMLCTDPDKRLNIKQVMASKWVADNTMVP 175
>00394
Length = 548
Score = 34.7 bits (78), Expect = 0.079, Method: Compositional matrix adjust.
Identities = 23/94 (24%), Positives = 43/94 (45%), Gaps = 5/94 (5%)
Frame = -2
Query: 137 RPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRL 196
+ +G+G F VY + + +A L + KA + + E E+ L+HPNI+R
Sbjct: 280 KEIGRGSFKTVYKGLDTELGVAVAWCELQDKKWNKAE-RQRFKEEAEMLKELQHPNIVRF 104
Query: 197 YGYFHDATR-----VYLILEYAPLGTVYRELQKL 225
+ Y+ + + L+ E GT+ L++
Sbjct: 103 FDYWEEHNHRNRKVIILVTELMTSGTLKTYLKRF 2
>18401
Length = 463
Score = 32.7 bits (73), Expect = 0.26, Method: Compositional matrix adjust.
Identities = 16/63 (25%), Positives = 29/63 (46%)
Frame = -3
Query: 287 TTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEF 346
+T+ T Y PE+I D+WS+G + +E G F+ + +E + R+
Sbjct: 458 STIVSTRHYRAPEVILELGWSHPCDVWSVGCIMFELYTGYTLFQTHDNKEHLAMMERILG 279
Query: 347 TFP 349
+ P
Sbjct: 278 SLP 270
>20773
Length = 391
Score = 32.0 bits (71), Expect = 0.48, Method: Compositional matrix adjust.
Identities = 17/54 (31%), Positives = 28/54 (51%)
Frame = -1
Query: 330 EANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWI 383
+ + ++R SR F VT+ +L+ RLL ++PSQR L HP++
Sbjct: 388 SGSCWSGLHRRRSRPVFPHTTVVTQHFYNLVQRLLTYDPSQRLTPDLALSHPFV 227
>21800
Length = 855
Score = 32.0 bits (71), Expect = 0.49, Method: Compositional matrix adjust.
Identities = 17/46 (36%), Positives = 26/46 (56%), Gaps = 5/46 (10%)
Frame = +2
Query: 237 ITELANALSYCHSK-RVIHRDIKPENLLLGSAG----ELKIADFGW 277
I ++ L+Y H+K +IH DIKPEN+L+ +L + F W
Sbjct: 650 IRQVLEGLNYLHAKCNIIHTDIKPENILICVDDNYIRKLAVDAFEW 787
>36481
Length = 806
Score = 32.0 bits (71), Expect = 0.51, Method: Compositional matrix adjust.
Identities = 32/141 (22%), Positives = 65/141 (46%), Gaps = 8/141 (5%)
Frame = +2
Query: 132 DFEIGRPLGKGKFGNVYLAREKQSKFILALKVL--FKAQLEKAGVE-HQLRREVEIQSHL 188
D ++ G+G FG V ++ +ALK++ E A +E + L + E H
Sbjct: 365 DMKLCPHWGEGTFGKVVQCKDLLKGDDIALKIIKNVDKYREAAKLEINVLEKLREKDPHA 544
Query: 189 RHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKF-----DEQRTATYITELANA 243
+H + L + + ++ + + LG + K + + ++ R +Y +L A
Sbjct: 545 KHMCVQMLDWFDYHG---HVCISFHMLGLSVFDFLKDNSYGAYPIEQVRHISY--QLCYA 709
Query: 244 LSYCHSKRVIHRDIKPENLLL 264
+++ H ++ H D+KPEN+L
Sbjct: 710 VNFLHENQLTHTDLKPENILF 772
>19872
Length = 446
Score = 31.6 bits (70), Expect = 0.53, Method: Compositional matrix adjust.
Identities = 14/41 (34%), Positives = 25/41 (60%), Gaps = 4/41 (9%)
Frame = +3
Query: 349 PDFVTEGA----RDLISRLLKHNPSQRPMLREVLEHPWITA 385
PDF + L+ ++L H+P+QRP R++L+ P++ A
Sbjct: 99 PDFTKDADLHNQSALLRQMLSHDPTQRPSSRDLLQSPYLPA 221
>17932
Length = 597
Score = 28.1 bits (61), Expect(2) = 0.76, Method: Compositional matrix adjust.
Identities = 14/31 (45%), Positives = 16/31 (51%), Gaps = 2/31 (6%)
Frame = -2
Query: 313 WSLGVLCYEFLVGKPPF--EANTYQETYKRI 341
WSLGV YE L G PF + + TY I
Sbjct: 593 WSLGVCAYEMLFGCTPFTDDDGSMVATYNNI 501
Score = 21.6 bits (44), Expect(2) = 0.76, Method: Compositional matrix adjust.
Identities = 14/32 (43%), Positives = 20/32 (62%)
Frame = -3
Query: 352 VTEGARDLISRLLKHNPSQRPMLREVLEHPWI 383
V++ ARDLIS+LL S R E+ +HP+
Sbjct: 460 VSKEARDLISQLLSDGKS-RLGWPELQQHPFF 368
>16350
Length = 1108
Score = 29.6 bits (65), Expect = 2.1, Method: Compositional matrix adjust.
Identities = 12/39 (30%), Positives = 23/39 (58%), Gaps = 1/39 (2%)
Frame = +3
Query: 358 DLISRLLKHNPSQRPMLREVLEHPWITANS-SKPSNCQN 395
D ++ +L+ +P QR + L+HPW+ ++ +PS Q
Sbjct: 762 DFLAPMLEFDPEQRATAAQSLQHPWLKLDA*PEPSGSQQ 878
>20513
Length = 405
Score = 29.3 bits (64), Expect = 2.9, Method: Compositional matrix adjust.
Identities = 12/39 (30%), Positives = 23/39 (58%), Gaps = 1/39 (2%)
Frame = -1
Query: 358 DLISRLLKHNPSQRPMLREVLEHPWITANS-SKPSNCQN 395
D ++ +L+ +P QR + L+HPW+ ++ +PS Q
Sbjct: 282 DFLAPMLEFDPEQRATAAQSLQHPWLKLDA*PEPSGSQQ 166
>17644
Length = 463
Score = 27.7 bits (60), Expect = 8.1, Method: Compositional matrix adjust.
Identities = 13/32 (40%), Positives = 19/32 (59%)
Frame = +3
Query: 352 VTEGARDLISRLLKHNPSQRPMLREVLEHPWI 383
VT+ BL+ RLL ++PSQR L HP++
Sbjct: 69 VTQHFYBLVQRLLTYDPSQRLTPDLALSHPFV 164
>18929
Length = 440
Score = 27.7 bits (60), Expect = 9.8, Method: Compositional matrix adjust.
Identities = 11/38 (28%), Positives = 22/38 (57%)
Frame = +1
Query: 348 FPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITA 385
F + ++ + +I R++ +P QRP ++L HP + A
Sbjct: 34 FINTISVELQQVIRRMMSPDPRQRPTANQLLAHPTLAA 147
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000321591 | hsapiens_gene_ensembl |
Serine/threonine-protein kinase 6 (EC 2.7.11.1) (Aurora kinase A)
(Aurora-A) (Serine/threonine kinase 15) (Aurora/IPL1-related kinase 1)
(Aurora-related kinase 1) (hARK1) (Breast-tumor-amplified kinase).
[Source:Uniprot/SWISSPROT;Acc:O14965]
(403 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
21433 184 3e-69
15910 120 8e-28
03240 119 2e-27
01060 117 6e-27
00300 114 8e-26
30755 110 1e-24
18484 110 1e-24
18921 107 7e-24
12721 105 4e-23
14420 101 5e-22
01707 99 3e-21
14126 98 5e-21
09606 97 8e-21
06405 97 9e-21
09007 94 8e-20
13592 93 2e-19
13212 92 3e-19
01392 91 1e-18
01756 87 1e-17
13066 87 1e-17
11780 80 2e-17
04591 86 2e-17
01718 86 3e-17
17975 85 4e-17
31885 84 7e-17
27546 83 2e-16
00486 82 3e-16
21079 82 6e-16
00392 80 1e-15
01966 79 3e-15
19761 76 2e-14
19094 70 6e-14
26560 75 7e-14
29581 72 4e-13
20152 69 3e-12
27405 68 7e-12
26711 66 3e-11
19301 65 5e-11
38560 65 6e-11
14477 64 1e-10
04852 64 1e-10
06358 64 1e-10
04138 64 2e-10
21808 63 2e-10
00715 62 5e-10
14116 61 6e-10
28157 61 8e-10
12672 61 9e-10
07940 61 1e-09
03508 61 1e-09
26009 41 3e-09
12786 59 3e-09
18663 58 7e-09
28638 56 3e-08
02638 53 2e-07
11185 52 3e-07
25019 52 4e-07
29590 39 1e-06
27274 50 2e-06
31120 49 4e-06
37602 49 4e-06
07833 48 6e-06
32000 48 6e-06
07291 48 8e-06
01106 47 2e-05
18481 45 6e-05
32957 45 6e-05
31489 44 1e-04
16708 44 1e-04
17253 44 1e-04
20640 44 1e-04
07836 43 3e-04
20559 40 3e-04
17300 42 4e-04
11404 41 0.001
21210 40 0.001
21418 40 0.002
20160 39 0.006
00638 38 0.006
31789 37 0.018
36002 36 0.023
37063 35 0.043
20655 35 0.068
00394 35 0.079
18401 33 0.26
20773 32 0.48
21800 32 0.49
36481 32 0.51
19872 32 0.53
17932 28 0.76
16350 30 2.1
20513 29 2.9
17644 28 8.1
18929 28 9.8
>21433
Length = 590
Score = 184 bits (467), Expect(2) = 3e-69, Method: Compositional matrix adjust.
Identities = 93/136 (68%), Positives = 107/136 (78%)
Frame = +2
Query: 231 QRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLC 290
+RTA YI +L++AL YCH ++VIHRDIKPENLLLG G+LKIADFGWSVHAPSSRRTT+C
Sbjct: 167 KRTACYIYQLSSALEYCHYRKVIHRDIKPENLLLGLKGDLKIADFGWSVHAPSSRRTTMC 346
Query: 291 GTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPD 350
GTLDYLPPEM+EG+ HDE VDLWSLGVLCYEFLVG PP + + R P
Sbjct: 347 GTLDYLPPEMVEGKTHDENVDLWSLGVLCYEFLVGTPPLRPSPTRPPTPASPRWTSGSPS 526
Query: 351 FVTEGARDLISRLLKH 366
VT GARDLIS+LL+H
Sbjct: 527 IVTPGARDLISKLLRH 574
Score = 95.9 bits (237), Expect(2) = 3e-69, Method: Compositional matrix adjust.
Identities = 44/64 (68%), Positives = 54/64 (84%), Gaps = 1/64 (1%)
Frame = +3
Query: 176 HQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDE-QRTA 234
HQLRRE+EIQSHLRH NILR++GYFHD TRVYLILE+AP G +Y+ELQ+ KFDE ++ A
Sbjct: 3 HQLRREIEIQSHLRHDNILRMFGYFHDKTRVYLILEFAPKGELYKELQRCHKFDENEQHA 182
Query: 235 TYIT 238
Y +
Sbjct: 183 IYTS 194
>15910
Length = 1361
Score = 120 bits (302), Expect = 8e-28, Method: Compositional matrix adjust.
Identities = 61/177 (34%), Positives = 104/177 (58%), Gaps = 8/177 (4%)
Frame = +2
Query: 226 SKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLL---LGSAGELKIADFGWS-VHA 281
++ E+ A I+++ + + Y H+ V+HRD+KPENLL + +LK+ADFG S +
Sbjct: 449 GQYTEKDAARAISDILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLADFGLSRIIE 628
Query: 282 PSSRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRI 341
P + +T+CGT Y PE+++G + VD+WS+GV+ Y L G PF A E Y++I
Sbjct: 629 PEVQMSTVCGTPGYCAPEVLKGDKYTPSVDMWSVGVIAYILLCGYEPFFAENEFEMYRKI 808
Query: 342 SRVEFTFPD----FVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQ 394
+ E+ F + ++E A+D++ +LL +P +R E L PW+ ++K +N +
Sbjct: 809 IKGEYKFDEEYWSEISENAKDVVRKLLVIDPKKRLTATEALRLPWVKGVATKTTNME 979
>03240
Length = 1683
Score = 119 bits (298), Expect = 2e-27, Method: Compositional matrix adjust.
Identities = 86/283 (30%), Positives = 133/283 (46%), Gaps = 52/283 (18%)
Frame = -3
Query: 133 FEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPN 192
FE + LG G FG V L R+ + + A+K L K+ + K ++ E +I + +
Sbjct: 1285 FEKIKTLGVGAFGEVSLCRKNDTGMLYAMKTLRKSDVLKRNQVAHVKAERDILAEADNEW 1106
Query: 193 ILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRV 252
+++LY F D +Y +++Y P G + L ++ DE Y+ EL A+ H
Sbjct: 1105 VVKLYYSFQDHNYLYFVMDYVPGGDLMGLLIRMEILDEPLARFYVAELVQAIESVHRMGF 926
Query: 253 IHRDIKPENLLLGSAGELKIADFG------WS----------VHA--------------- 281
IHRDIKP+N+L+ G +K+ DFG W+ HA
Sbjct: 925 IHRDIKPDNILIDRNGHIKLTDFGLCTGFRWTHNSKYYQRDGTHARQDSMEVKCQLDEQC 746
Query: 282 ------PSSRRT---------TLCGTLDYLPPEMIEGRM--HDEKVDLWSLGVLCYEFLV 324
P RR +L GT +Y+ PE++ R+ + D WS+GV+ +E LV
Sbjct: 745 QCEILKPLERRRKREQRCLAHSLVGTPNYIAPEVL-SRLGGYTSVCDWWSVGVILFEMLV 569
Query: 325 GKPPFEANTYQET-YKRIS---RVEFTFPDFVTEGARDLISRL 363
G PPF ANT ET YK I+ ++ +++ A+DLI RL
Sbjct: 568 GHPPFYANTPAETQYKVINWKDMLKIPRESNLSQPAKDLILRL 440
>01060
Length = 1800
Score = 117 bits (294), Expect = 6e-27, Method: Compositional matrix adjust.
Identities = 83/305 (27%), Positives = 145/305 (47%), Gaps = 36/305 (11%)
Frame = +1
Query: 129 ALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHL 188
AL D + +G+G +G VY R + + LA+K + + + + GV RE+ + L
Sbjct: 67 ALSDLTDFQKIGEGTYGVVYKCRHRATGRKLAMKKI-RLRGSEDGVPSSAIREIAMLREL 243
Query: 189 RHPNILRLYGYFHDATRVYLILEY--APLGTVYRELQKLSKFDEQRTATYITELANALSY 246
RH NI+ L + R++L+ E+ L + + D + +Y+ ++ + +
Sbjct: 244 RHTNIVCLEDVIMEDERLFLVFEFLSMDLKMYIDKFPEGVVLDRRLVKSYVFQIVTGIXF 423
Query: 247 CHSKRVIHRDIKPENLLLGSAGELKIADFGW--SVHAPSSRRTTLCGTLDYLPPEMIEG- 303
CH +R++HRD+KP+NLL+ G +KIADFG + P T TL Y PE++ G
Sbjct: 424 CHQRRIVHRDLKPQNLLINHTGAIKIADFGMARTFALPVRAYTHEVVTLWYRAPEILMGA 603
Query: 304 RMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRV-----EFTFPDF------- 351
+ VD+WS+G + + L+ P F+ ++ + +I R+ E T+P+F
Sbjct: 604 SKYSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKLPAFN 783
Query: 352 -----------------VTEGARDLISRLLKHNPSQRPMLREVLEHPWI--TANSSKPSN 392
+ DLI R LK +P+QR +++L+H + S KP +
Sbjct: 784 GMFPLWKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYFLNVDTSVKPVD 963
Query: 393 CQNKE 397
+ E
Sbjct: 964 VPSPE 978
>00300
Length = 2318
Score = 114 bits (285), Expect = 8e-26, Method: Compositional matrix adjust.
Identities = 74/257 (28%), Positives = 125/257 (48%), Gaps = 10/257 (3%)
Frame = -1
Query: 136 GRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILR 195
G +G+G+FG VY A + ++ALK + K Q ++ E++I ++H N+++
Sbjct: 1643 GNKIGEGQFGKVYTAVNMSTGELMALKEM-KFQPNDLQQLREMCDEIKIFEGIQHENLVK 1467
Query: 196 LYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHR 255
YG + + +EY GT+ E K+ E Y E+ A+++ H ++HR
Sbjct: 1466 YYGVEVHKDEMLMFMEYCDTGTI-EEAAKMG-LPEYLIRRYTREIVLAVNHLHENSIVHR 1293
Query: 256 DIKPENLLLGSAGELKIADFGWSVHAPSSRRT-----TLCGTLDYLPPEMI---EGRMHD 307
DIK N+ L S G +K+ DFG SV S L GT Y+ PE+ + +
Sbjct: 1292 DIKGANIFLTSNGHVKLGDFGCSVKLKSHTTMPGEFHNLVGTTAYMAPEVFTQNDQGGYG 1113
Query: 308 EKVDLWSLGVLCYEFLVGKPPFE--ANTYQETYKRISRVEFTFPDFVTEGARDLISRLLK 365
D+WSLG + E GK P+ N YQ YK + PD ++ + + ++
Sbjct: 1112 RAADIWSLGCVVIEMATGKRPWHDLDNNYQIMYKVGIGHKPAVPDSLSVEGKHFLDLIMC 933
Query: 366 HNPSQRPMLREVLEHPW 382
H+P+QR + ++L+H +
Sbjct: 932 HDPAQRALASQLLDHTF 882
>30755
Length = 1137
Score = 110 bits (275), Expect = 1e-24, Method: Compositional matrix adjust.
Identities = 60/165 (36%), Positives = 91/165 (55%), Gaps = 7/165 (4%)
Frame = +2
Query: 228 FDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRT 287
F E+RT Y E+ +AL Y HS+ +I+RD+K ENLLL G +K+ADFG + RT
Sbjct: 23 FTEERTRFYGAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCKEDITYGRT 202
Query: 288 T--LCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVE 345
T CGT +YL PE+++ + VD W GV+ YE + G+ PF + + I +
Sbjct: 203 TKTFCGTPEYLAPEVLDDNDYGRAVDWWGTGVVMYEMICGRLPFYNRDHDVLFTLILVED 382
Query: 346 FTFPDFVTEGARDLISRLLKHNPSQR-----PMLREVLEHPWITA 385
FP +T+ A+ L+S LL +P R ++E+ HP+ +
Sbjct: 383 VKFPRNITDEAKSLLSGLLAKDPRNRLGGGQDDVKEIQAHPFFAS 517
>18484
Length = 635
Score = 110 bits (275), Expect = 1e-24, Method: Compositional matrix adjust.
Identities = 57/156 (36%), Positives = 89/156 (57%), Gaps = 2/156 (1%)
Frame = +1
Query: 218 VYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGW 277
+YR +Q+ KF E A Y E+A L + H + +I+RD+K +N++L S G +KIADFG
Sbjct: 7 MYR-IQQEGKFKEPVAAFYAAEIAVGLFFLHDQGIIYRDLKLDNVMLDSEGHIKIADFGM 183
Query: 278 SVHAPSSRRTT--LCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQ 335
+ TT CGT DY+ PE++ + + + VD W+ GVL +E L G+PPF+
Sbjct: 184 CKEGMTGDATTRTFCGTPDYIAPEIVLYQPYSKSVDWWAYGVLLFEMLAGQPPFDGEDED 363
Query: 336 ETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQR 371
E + I+ ++P ++ A L LL NP++R
Sbjct: 364 ELFSSITDHNVSYPKAMSREAVSLCKGLLMKNPTKR 471
>18921
Length = 697
Score = 107 bits (268), Expect = 7e-24, Method: Compositional matrix adjust.
Identities = 64/199 (32%), Positives = 109/199 (54%), Gaps = 3/199 (1%)
Frame = +2
Query: 133 FEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPN 192
F+I LG+G +G+V+ + K++ +LA+K Q+ ++ +E+ I
Sbjct: 35 FDILGKLGEGSYGSVFKSLHKETGQVLAIK-----QVPVDTDLQEIIKEISIMQQCDSKY 199
Query: 193 ILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSK-FDEQRTATYITELANALSYCHSKR 251
I++ YG + T +++++EY G+V ++ +K E+ AT + L Y HS+R
Sbjct: 200 IVKYYGSYFKNTDLWIVMEYCGAGSVSDIMRLRNKTLVEREIATILYYTLKGLXYLHSRR 379
Query: 252 VIHRDIKPENLLLGSAGELKIADFGWS--VHAPSSRRTTLCGTLDYLPPEMIEGRMHDEK 309
IHRDIK N+LL + G K+ADFG + + ++R T+ GT ++ PE+I+ +D
Sbjct: 380 KIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTPYWMAPEVIQEIGYDCV 559
Query: 310 VDLWSLGVLCYEFLVGKPP 328
D+WSLG+ E GKPP
Sbjct: 560 ADIWSLGITALEMAEGKPP 616
>12721
Length = 821
Score = 105 bits (261), Expect = 4e-23, Method: Compositional matrix adjust.
Identities = 69/247 (27%), Positives = 123/247 (49%), Gaps = 5/247 (2%)
Frame = +1
Query: 130 LEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLR 189
L+DF +G+G G V +A + + +A+K K L K L EV +
Sbjct: 94 LDDF---MKIGEGSTGIVCIATSRDGR-QMAVK---KMDLRKQQRRELLFNEVVVMRDYH 252
Query: 190 HPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHS 249
HPNI+ +Y + +++++E+ G ++ ++ DE + AT AL++ H+
Sbjct: 253 HPNIVEMYNSYLVNDELWVVMEFME-GGALTDIVTNNRMDEVQIATVCRACLKALAFLHA 429
Query: 250 KRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSS--RRTTLCGTLDYLPPEMIEGRMHD 307
VIHRDIK +++LL G++K+ DFG+ +R +L GT ++ PE+I +
Sbjct: 430 NGVIHRDIKSDSILLSHDGKVKLXDFGFCAQVTQDLQKRKSLVGTPYWMAPEVISRLPYG 609
Query: 308 EKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRV---EFTFPDFVTEGARDLISRLL 364
+VD+WSLG++ E + +PPF + +RI + + ++ + I R+L
Sbjct: 610 PEVDIWSLGIMVMEMIDAEPPFFNEPPLQAMRRIRDMPPPKLRNTHKISPRLQGFIDRML 789
Query: 365 KHNPSQR 371
+P QR
Sbjct: 790 VRDPHQR 810
>14420
Length = 528
Score = 101 bits (252), Expect = 5e-22, Method: Compositional matrix adjust.
Identities = 48/151 (31%), Positives = 87/151 (57%), Gaps = 2/151 (1%)
Frame = +2
Query: 181 EVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITEL 240
E+ + ++PNI+ + +++++E+ G++ + + + DE + A E
Sbjct: 50 EILVMRENQNPNIVNYLDSYLVGEELWVVMEFLAGGSLTDVVTE-TCMDEGQIAAVCREC 226
Query: 241 ANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAP--SSRRTTLCGTLDYLPP 298
AL + H +VIHRDIK +N+LLG G +K+ DFG+ S+R+T+ GT ++ P
Sbjct: 227 LQALEFLHENQVIHRDIKSDNILLGMDGSVKLTDFGFCAQLSPEQSKRSTMVGTPYWMAP 406
Query: 299 EMIEGRMHDEKVDLWSLGVLCYEFLVGKPPF 329
E++ + + VD+WSLGV+C E + G+PP+
Sbjct: 407 EVVTRKQYGPTVDIWSLGVMCIEMIEGEPPY 499
>01707
Length = 757
Score = 99.0 bits (245), Expect = 3e-21, Method: Compositional matrix adjust.
Identities = 58/201 (28%), Positives = 108/201 (53%), Gaps = 4/201 (1%)
Frame = +1
Query: 130 LEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLR 189
+E +E +G+G +G V+ R K++ ++A+K +++ + ++ RE+ + L+
Sbjct: 61 MEKYEKIGKIGEGSYGVVFKCRNKETSQLVAIKKFVESE-DDPLIKKIAMREIRMLKQLK 237
Query: 190 HPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSK-FDEQRTATYITELANALSYCH 248
HPN++RL F R++L+ +Y T+ EL + + E I + A+++CH
Sbjct: 238 HPNLVRLIEVFRRKKRLHLVFDYVD-HTLLNELDRYPRGLPEPMVKRIIYQTLLAVNFCH 414
Query: 249 SKRVIHRDIKPENLLLGSAGELKIADFGWS--VHAPSSRRTTLCGTLDYLPPEMIEGRM- 305
IHRD+KPEN+L+ G++K+ DFG++ + P T T Y PE++ G
Sbjct: 415 QYNTIHRDVKPENILITRQGQVKLCDFGFARILTGPGDEYTDYVATRWYRAPELLVGDTQ 594
Query: 306 HDEKVDLWSLGVLCYEFLVGK 326
+ VD+W++G + E L G+
Sbjct: 595 YGPPVDVWAIGCVFAELLTGQ 657
>14126
Length = 1265
Score = 98.2 bits (243), Expect = 5e-21, Method: Compositional matrix adjust.
Identities = 86/332 (25%), Positives = 146/332 (43%), Gaps = 46/332 (13%)
Frame = +3
Query: 116 SKQKNEESKKRQWALEDFEIGRPLGKGKFGNVYLARE--KQSKFILALKVLFKAQLEKAG 173
S+ + S++R + +E +G G +G VY AR+ Q +F+ ++ E G
Sbjct: 144 SESAAKMSRRRDSTEQKYEEVAVIGNGAYGTVYKARDLRNQGEFVAMKRIRLNNTEE--G 317
Query: 174 VEHQLRREVEIQSHLR---HPNILRLYGYFHDAT-----RVYLILEYA--PLGTVYRELQ 223
+ RE+ + L HPN++RL H+ R+ L+ EY L T Y
Sbjct: 318 MPMMAIREISMLKQLEQYEHPNVVRLLDVSHNTITDREIRLNLVFEYIEHDLAT-YLAKC 494
Query: 224 KLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS-VHAP 282
R + +L N + + HS R++HRD+KP+NLL+ G LK+ADFG + +++
Sbjct: 495 PSPGLGPDRIKDLMLQLLNGVDFLHSNRIVHRDLKPQNLLISKDGRLKLADFGLARIYSF 674
Query: 283 SSRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRIS 342
TT+ TL Y PE++ + VD+WS G + E + F+ ++ + K+I
Sbjct: 675 HMALTTVVVTLWYRSPEVLMQAEYGTSVDIWSCGCIFAELFTRRALFKGSSEFDQLKKIF 854
Query: 343 RV-----EFTFPDFVTEG----------------------ARDLISRLLKHNPSQRPMLR 375
V +P+ V+ A+DL+ ++L +R R
Sbjct: 855 EVIGLPPAGDWPEGVSVHRNSFRPTPPVPLQTLVPEMDPQAKDLMEKMLVFKSGRRISSR 1034
Query: 376 EVLEHPWITAN------SSKPSNCQNKESASK 401
E L HP++ + SS S +N S +
Sbjct: 1035ESLLHPYLRDDLDSIRTSSSLSTSENDSSDGR 1130
>09606
Length = 1300
Score = 97.4 bits (241), Expect = 8e-21, Method: Compositional matrix adjust.
Identities = 66/285 (23%), Positives = 126/285 (44%), Gaps = 34/285 (11%)
Frame = -3
Query: 130 LEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLR 189
+E+F + LGKG+ +Y R K + +A+ + K + ++ V + +
Sbjct: 1118 MENFVLYEELGKGEHSIIYKGRRKGTINFVAIHCIEKCK------RPEVTNTVRMTHDIS 957
Query: 190 HPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHS 249
HPN+++ + ++ + ++L++E G++ L + E + L L Y HS
Sbjct: 956 HPNVVQFHEWYETSNHLWLVVELCTGGSLADILAQDHHLPETSIRDFGIHLVTGLHYIHS 777
Query: 250 KRVIHRDIKPENLLLGSAGELKIADFG----------------------WSVHAPSS--R 285
++ D++P +LL ++G LK ADFG W++ + +
Sbjct: 776 LGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQWNIQSAEEMMK 597
Query: 286 RTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVE 345
+ G+ Y+ PE+ +G DLW+LG + YE G PPF TY T ++ E
Sbjct: 596 QVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSGHPPFLGETYDITKDKVLNKE 417
Query: 346 FTFPDFVTEGAR----------DLISRLLKHNPSQRPMLREVLEH 380
F P +G+R +L+ LL+ + ++R +++H
Sbjct: 416 FPLPK--VKGSRLSAKPSPEFLNLLESLLQKDSTRRLSWASLVKH 288
>06405
Length = 1965
Score = 97.4 bits (241), Expect = 9e-21, Method: Compositional matrix adjust.
Identities = 68/260 (26%), Positives = 118/260 (45%), Gaps = 9/260 (3%)
Frame = +1
Query: 127 QWALEDFEIGRP--LGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEI 184
+W +E EI LG G++G+VY A K+ I+A+K L E + E I
Sbjct: 241 RWEIERTEIAMKHRLGGGQYGDVYEAMWKRYNKIVAVKTL----KEDTMALNDFLEEAAI 408
Query: 185 QSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTA-TYI-TELAN 242
++HPN+++L G Y++ E+ P G + L+ ++ + TA Y+ T++A+
Sbjct: 409 MKEMKHPNLVQLLGVCTREPPFYIVTEFMPHGNLLDYLRSSTREENGPTALMYMATQIAS 588
Query: 243 ALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGT---LDYLPPE 299
++Y +K IHRD+ N L+ + +K+ADFG + T G + + PE
Sbjct: 589 GMAYLETKNFIHRDLAARNCLVADSNMVKVADFGLARLMKDDTYTAHIGAKFPIKWTAPE 768
Query: 300 MIEGRMHDEKVDLWSLGVLCYEFLV-GKPPFEANTYQETYKRISR-VEFTFPDFVTEGAR 357
+ + D+W+ GVL +E G P+ E Y + R P
Sbjct: 769 GLAFNRFSTRSDIWAFGVLLWELATYGMSPYPGVELTEVYHLLERGYRMERPPGTPADVY 948
Query: 358 DLISRLLKHNPSQRPMLREV 377
L+ + + +P RP +E+
Sbjct: 949 ILMLKCWQWDPKDRPTFKEI 1008
>09007
Length = 1440
Score = 94.4 bits (233), Expect = 8e-20, Method: Compositional matrix adjust.
Identities = 71/264 (26%), Positives = 122/264 (46%), Gaps = 20/264 (7%)
Frame = -1
Query: 135 IGRPLGKGKFGNVYLA---REKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHP 191
+ + LG+G FG V A E K +A+K L K ++ K G E +E I L H
Sbjct: 867 LSKSLGQGHFGTVRQAIWTAESGEKVQVAVKCLSKDKIHKDGQE--FLKETAIMQMLDHE 694
Query: 192 NILRLYGYFHD-ATRVYLILEYAPLGTVYRELQKLS---KFDEQRTATYITELANALSYC 247
NI+R+YG D + L+ E AP+ ++ ++++S F R + ++ + +SY
Sbjct: 693 NIVRVYGVVMDNGADIMLVTELAPMRSLLECVKEVSARVDFSVPRLCDFSQQVCDGMSYL 514
Query: 248 HSKRVIHRDIKPENLLLGSAGELKIADFGWSV-------HAPSSRRTTLCGTLDYLPPEM 300
SKR++HRD+ N+LL S ++KI+D G S + S + L + + PE
Sbjct: 513 ESKRLVHRDLAARNILLFSKSKVKISDVGVSGALGAGKEYYQSQQTIHLQNAVAWCAPES 334
Query: 301 IEGRMHDEKVDLWSLGVLCYEFLV-GKPPFEANTYQETYKRIS-----RVEFTFPDFVTE 354
D+W+ GVL +EF G P+ Q+ + + R+E PD +
Sbjct: 333 FRNLCFSSASDVWAFGVLLWEFFTHGFQPWAGLNGQQIMEAVDAPQSQRLE--QPDLCPK 160
Query: 355 GARDLISRLLKHNPSQRPMLREVL 378
++ + + P +RP ++
Sbjct: 159 EYYAVMLKCWEQEPQRRPTFSQLF 88
>13592
Length = 980
Score = 93.2 bits (230), Expect = 2e-19, Method: Compositional matrix adjust.
Identities = 68/270 (25%), Positives = 128/270 (47%), Gaps = 14/270 (5%)
Frame = +2
Query: 139 LGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYG 198
+G+G+FG VY A + ++A+K + E +++ + E++I ++H N++R YG
Sbjct: 8 IGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETRALKN-VAEELKILEGIKHKNLVRYYG 184
Query: 199 YFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIK 258
+ + +E GT+ ++ E + + +L + ++ H ++HRDIK
Sbjct: 185 IEVHREELLIFMELCSEGTLESLVELTGGLPEALSRRFTAQLLSGVAELHKHGIVHRDIK 364
Query: 259 PENL-LLGSAGELKIADFGWSVHAPSSRRTTL-------CGTLDYLPPEMI---EGRMHD 307
N+ L+ + LK+ DFG +V + TT+ GT Y+ PE+ H
Sbjct: 365 TANIFLVDGSNSLKLGDFGSAVKIQA--HTTVPGELQGYVGTQAYMAPEVFTKTNSDGHG 538
Query: 308 EKVDLWSLGVLCYEFLVGKPP---FEANTYQETYKRISRVEFTFPDFVTEGARDLISRLL 364
D+WS+G + E GK P F++N +Q +K + P+ +++ D I L
Sbjct: 539 RLADIWSVGCVVVEMASGKRPWAQFDSN-FQIMFKVGMGEKPQAPESLSQEGHDFIDHCL 715
Query: 365 KHNPSQRPMLREVLEHPWITANSSKPSNCQ 394
+H+P QR E+LE + + + N +
Sbjct: 716 QHDPKQRLSAIELLEQNFCKSGRDEECNSE 805
>13212
Length = 1067
Score = 92.4 bits (228), Expect = 3e-19, Method: Compositional matrix adjust.
Identities = 60/188 (31%), Positives = 96/188 (51%), Gaps = 10/188 (5%)
Frame = -1
Query: 206 VYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLG 265
V+ +L + L ++ +L+K E + E+ AL + H VIHRDIK N+LL
Sbjct: 1049 VFRVLWWGALDSIMVDLEK--PMTEAQICYVCHEMCMALDFLHRHHVIHRDIKAGNVLLT 876
Query: 266 SAGELKIADFGWSVHAPSS--RRTTLCGTLDYLPPEMI-----EGRMHDEKVDLWSLGVL 318
GE+K+ADFG S + +R T GT ++ PE++ + +D K D+WSLGV
Sbjct: 875 IDGEVKLADFGVSAKNTQTQQKRDTFIGTPYWMAPEVVLCETLKDTPYDFKADIWSLGVT 696
Query: 319 CYEFLVGKPPFEANTYQETYKRISRVE---FTFPDFVTEGARDLISRLLKHNPSQRPMLR 375
EF +PP + +I + + P T+ +D I++ L +P+ RP
Sbjct: 695 LIEFAQIEPPNKEMHPMRVLIKIHKSDPPTLEKPKKWTKLFKDFIAKCLVKDPNLRPTAA 516
Query: 376 EVLEHPWI 383
E+LEHP++
Sbjct: 515 ELLEHPFM 492
>01392
Length = 1806
Score = 90.5 bits (223), Expect = 1e-18, Method: Compositional matrix adjust.
Identities = 57/189 (30%), Positives = 90/189 (47%), Gaps = 34/189 (17%)
Frame = -1
Query: 230 EQRTATYITELANALSYCHSKRVIHRDIKPENLL---LGSAGELKIADF----GWSVHAP 282
E+ + + +A AL + HSK + HRD+KPEN+L L +KI DF G S
Sbjct: 1794 EREASLVVRHIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGISCDGD 1615
Query: 283 SSRRTTL---CGTLDYLPPEMIEGRM-----HDEKVDLWSLGVLCYEFLVGKPPFEANTY 334
++ L G+ +Y+ PE+++ + +D++ DLWSLG++ Y L G PPF
Sbjct: 1614 GTKTPELLTPVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILYIMLCGYPPFYGQCG 1435
Query: 335 QET---------------YKRISRVEFTFPD----FVTEGARDLISRLLKHNPSQRPMLR 375
++ + I + FP ++ A+DLI LL P +R
Sbjct: 1434 EDCGWNRGEACHDCQDMLFNSIQDGHYKFPSQEWTSISSSAKDLIRHLLVREPRKRYSAA 1255
Query: 376 EVLEHPWIT 384
+VL+HPWI
Sbjct: 1254 DVLKHPWIC 1228
>01756
Length = 1858
Score = 87.0 bits (214), Expect = 1e-17, Method: Compositional matrix adjust.
Identities = 66/222 (29%), Positives = 106/222 (47%), Gaps = 16/222 (7%)
Frame = -3
Query: 139 LGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYG 198
+G+G FG V+ AR K++K ++A+K + EK G RE++I L H N++ L
Sbjct: 1718 IGQGTFGEVFKARCKKTKQVVAMKKVLMDN-EKEGFPITALREIKILQLLNHENVVDLIE 1542
Query: 199 YFH----DATR----VYLILEYA--PLGTVYRELQKLSKFDEQRTATYITELANALSYCH 248
A R YL+ E+ L + + + E + + +L N L Y H
Sbjct: 1541 ICSTKATSANRYKSMFYLVFEFCEHDLAGLLSNMSVVFNLPEIKEV--MKQLMNGLYYIH 1368
Query: 249 SKRVIHRDIKPENLLLGSAGELKIADFG----WSVHAPS-SRRTTLCGTLDYLPPEMIEG 303
+++HRD+K N+L+ G LK+ADFG +SV+ +R T TL Y PPE++ G
Sbjct: 1367 RNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRPPELLLG 1188
Query: 304 -RMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRV 344
R + +D W G + E P + T Q I+++
Sbjct: 1187 DRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQNQLTLITQL 1062
>13066
Length = 551
Score = 87.0 bits (214), Expect = 1e-17, Method: Compositional matrix adjust.
Identities = 50/164 (30%), Positives = 87/164 (53%), Gaps = 6/164 (3%)
Frame = +3
Query: 159 LALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTV 218
LA K++ K + VE RE+++ + L HP I++++ + ++ + +A G +
Sbjct: 60 LACKIIDKEKAPVDFVEKFFPRELDLLTKLDHPYIIQIHSILQRXPKNFIFMRFAERGDL 239
Query: 219 YRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS 278
+Q++ E++ + ++ AL+Y HS V HRD+K EN+LL S +K+ADFG++
Sbjct: 240 LTYIQEVGFVKEKQAKIWFYQMTTALNYLHSYDVAHRDLKCENILLSSHFNVKLADFGFA 419
Query: 279 VHAPSS-----RRTTLCGTLDYLPPEMIEGRMHDEKV-DLWSLG 316
+ T CG+ Y PE++ G + KV D WSLG
Sbjct: 420 CACITESGEKYMSRTYCGSAAYAAPEIVYGAPYAPKVADAWSLG 551
>11780
Length = 1713
Score = 80.1 bits (196), Expect(2) = 2e-17, Method: Compositional matrix adjust.
Identities = 57/202 (28%), Positives = 100/202 (49%), Gaps = 7/202 (3%)
Frame = +3
Query: 121 EESKKRQW--ALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQL 178
+E K W A +D EIG +GKG FG+VY + V K +K E
Sbjct: 561 QEFKSGGWVIAXQDLEIGEAIGKGDFGDVYKGMYRGQP------VAIKQLKDKDRGEQSF 722
Query: 179 RREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSK--FDEQRTATY 236
+E + + LRH N++RL G T ++L+ E+ G + L+ + ++ +
Sbjct: 723 LQEASVMTSLRHDNLVRLIGVVLGET-IFLVTEFMGKGNLVEYLRSRGRSVITKKDQINF 899
Query: 237 ITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYL 296
T+ A+ Y SKR++HRD+ N+L+ G+ K++DFG + S +T++ + +
Sbjct: 900 ATDTCAAMEYLESKRLVHRDLAARNVLVHDDGKAKVSDFGLAKFGDFS-QTSVKFPIKWT 1076
Query: 297 PPEMI-EGRMHDE--KVDLWSL 315
PE + E ++H + V+LW +
Sbjct: 1077APEALRENKIH*QVRHVELWHI 1142
Score = 26.6 bits (57), Expect(2) = 2e-17, Method: Compositional matrix adjust.
Identities = 16/72 (22%), Positives = 33/72 (45%), Gaps = 2/72 (2%)
Frame = +1
Query: 309 KVDLWSLGVLCYE-FLVGKPPFEANTYQETYKRISR-VEFTFPDFVTEGARDLISRLLKH 366
K D+WS G+L +E + G+ P+ + + R P+ ++ + +
Sbjct: 1114 KSDMWSFGILLWEIYSFGRVPYPRIPLTDVVMHVERGYRMEAPEGCPPEIYSIMKQAWEL 1293
Query: 367 NPSQRPMLREVL 378
+P++RP + VL
Sbjct: 1294 DPNERPTFKSVL 1329
>04591
Length = 1117
Score = 86.3 bits (212), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 60/184 (32%), Positives = 88/184 (47%), Gaps = 12/184 (6%)
Frame = -2
Query: 171 KAGVEHQLRREVEIQSHLRHPNILRLYGYFHD--------ATRVYLILEYAP--LGTVYR 220
K G RE++I L H N+++L H + YLI EY L +
Sbjct: 1101 KEGFPITALREIKILQQLEHENVVQLQEICHTQAGPYNRYKSTFYLIFEYCDYDLAGLLN 922
Query: 221 ELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSV- 279
L+ KF +++L N L Y H+K+++HRDIK N+LL G LK+ADFG S
Sbjct: 921 NLR--VKFSLADKKNLMSQLLNGLFYIHTKQILHRDIKAANILLTRDGVLKLADFGLSRP 748
Query: 280 HAPSSRRTTLCGTLDYLPPEMIEG-RMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETY 338
S R T TL Y PPE++ G R + ++D+W +G + E KP + + Q
Sbjct: 747 WVKSKRLTNRVVTLWYRPPELLLGEREYGPEIDMWGVGCIMAEMWSRKPLMQGRSEQHQL 568
Query: 339 KRIS 342
I+
Sbjct: 567 SLIT 556
>01718
Length = 959
Score = 85.9 bits (211), Expect = 3e-17, Method: Compositional matrix adjust.
Identities = 62/209 (29%), Positives = 99/209 (47%), Gaps = 11/209 (5%)
Frame = +3
Query: 130 LEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLR 189
L+DF I +G G F V+ + + ++ALK+ H + REV++ + L+
Sbjct: 147 LDDF-ICEKIGAGFFSEVFKVTHRITGQVMALKMN-----TMTSNRHNMLREVQLLNRLQ 308
Query: 190 HPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTAT----YITELANALS 245
H NILR G +++ + EY P G + Q L K DE+ T LA L
Sbjct: 309 HANILRFMGVCVHEGQLHALTEYIPSGNLE---QLLEKKDEELPWTQRIQLTLGLARGLD 479
Query: 246 YCHSKRVIHRDIKPENLLL----GSAGELKIADFGWSVHAP---SSRRTTLCGTLDYLPP 298
Y HS R IHRD+ +N+L+ IADFG + P + G+ ++ P
Sbjct: 480 YLHSTRFIHRDLTSKNILIRREDNHGYHAVIADFGLATKIPDPLDKEKLPTVGSPYWMAP 659
Query: 299 EMIEGRMHDEKVDLWSLGVLCYEFLVGKP 327
E++ G ++E+ DL+S+G++ E P
Sbjct: 660 EVLNGHFYNERADLFSVGIIMCEITARIP 746
>17975
Length = 449
Score = 85.1 bits (209), Expect = 4e-17, Method: Compositional matrix adjust.
Identities = 51/137 (37%), Positives = 80/137 (58%), Gaps = 2/137 (1%)
Frame = +3
Query: 144 FGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDA 203
F V LAR + +A+KV+ K +L++ H L +EV ++HPN++RLY
Sbjct: 6 FAVVKLARHVFTGEKVAVKVIDKTKLDEVSRSH-LFQEVRCMKLVQHPNVVRLYEVIDTQ 182
Query: 204 TRVYLILEYAPLGTVYRELQKLSKFDEQRTAT-YITELANALSYCHSKRVIHRDIKPENL 262
T++YLILE G +Y + + S E++ A Y ++ A+SYCH V+HRD+KPEN+
Sbjct: 183 TKLYLILELGDGGDMYDYIMRHSGGLEEKLAKRYFRQIVEAISYCHKLHVVHRDLKPENV 362
Query: 263 LLGSA-GELKIADFGWS 278
+ G +K+ DFG+S
Sbjct: 363 VFFEKPGLVKLTDFGFS 413
>31885
Length = 529
Score = 84.3 bits (207), Expect = 7e-17, Method: Compositional matrix adjust.
Identities = 48/158 (30%), Positives = 81/158 (51%), Gaps = 6/158 (3%)
Frame = -2
Query: 182 VEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELA 241
V++ + L HP ++ L+ F D ++++++ G + +Q+ F E Y+ +LA
Sbjct: 519 VDMLTRLDHPFLVNLWYAFQDEEDLFMVVDLFLGGDLRYHMQQEVSFREDCVKFYLCQLA 340
Query: 242 NALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSR-RTTLCGTLDYLPPEM 300
L Y S++++HRDIKP+N+LL G + DF + T+ GT Y+ PE+
Sbjct: 339 LVLDYLRSQKIVHRDIKPDNILLDEQGHCHVTDFNIATQLEDDELATSTSGTRPYMAPEV 160
Query: 301 I-----EGRMHDEKVDLWSLGVLCYEFLVGKPPFEANT 333
E R + VD WSLGV +E L + PF ++
Sbjct: 159 YGVAINERRGYGFPVDWWSLGVSLFELLKKRRPFSVHS 46
>27546
Length = 426
Score = 82.8 bits (203), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 42/120 (35%), Positives = 70/120 (58%)
Frame = -1
Query: 159 LALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTV 218
LA K++ KA+ V+ RE+EI + L HPNI++++ ++++ + YA G +
Sbjct: 396 LACKIIDKAKAPIDFVKKFFPRELEILTRLDHPNIIQIHSILQRGPKIFIFMRYAEKGDM 217
Query: 219 YRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS 278
++K DE +T + ++A AL Y HS + HRD+K EN+LL +KIADFG++
Sbjct: 216 LSHIKKTGPIDEAQTKVWFFQMAKALQYLHSHDIAHRDLKCENILLSKRLNVKIADFGFA 37
>00486
Length = 797
Score = 82.0 bits (201), Expect = 3e-16, Method: Compositional matrix adjust.
Identities = 35/84 (41%), Positives = 53/84 (63%)
Frame = -2
Query: 288 TLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFT 347
T CGT++Y+ PE++ H + VD WSLG L Y+ L G PPF A ++T +I + +
Sbjct: 781 TFCGTIEYMAPEILTRTGHGKAVDWWSLGALMYDMLTGSPPFTAENRKKTIDKILKGKLN 602
Query: 348 FPDFVTEGARDLISRLLKHNPSQR 371
P ++T AR LI +LL+ NP++R
Sbjct: 601 LPPYLTNEARGLIKKLLRKNPAER 530
>21079
Length = 878
Score = 81.6 bits (200), Expect = 6e-16, Method: Compositional matrix adjust.
Identities = 42/148 (28%), Positives = 79/148 (53%), Gaps = 4/148 (2%)
Frame = +1
Query: 190 HPNILRLYGYFHDATRVYLILEYAPLGTVY-RELQKLSKFDEQRTATYITELANALSYCH 248
HP +L L+ F + L++E+ G ++ R ++ E+ ++ ++ + + Y H
Sbjct: 1 HPKLLMLWDAFEAPRTMVLVMEFVGAGELFERVIRDDFVLTERDCVHFVRQICSGVGYMH 180
Query: 249 SKRVIHRDIKPENLLLGS--AGELKIADFGWS-VHAPSSRRTTLCGTLDYLPPEMIEGRM 305
++ ++H D+KPEN+L S + ++KI DFG + + P L GT +++ PE++
Sbjct: 181 TQSILHLDLKPENVLCVSDNSNQIKIIDFGLARFYKPGDSLQVLFGTPEFIAPEVVNYDE 360
Query: 306 HDEKVDLWSLGVLCYEFLVGKPPFEANT 333
+ D+WS+GV+CY L G P T
Sbjct: 361 INFTTDMWSIGVICYILLSGLSPSRVTT 444
>00392
Length = 668
Score = 80.5 bits (197), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 48/175 (27%), Positives = 91/175 (52%), Gaps = 9/175 (5%)
Frame = +3
Query: 177 QLRREVEIQSHLRHPNILRLYGYFHDATR-----VYLILEYAPLGTVYRELQKLSKFDEQ 231
+ + E E+ L+HPNI+R + Y+ + + L+ E GT+ L++ K + +
Sbjct: 69 RFKEEAEMLKELQHPNIVRFFDYWEEHNHRNRKVIILVTELMTSGTLKTYLKRFKKPNVK 248
Query: 232 RTATYITELANALSYCHSKR--VIHRDIKPENLLL-GSAGELKIADFGWSVHAPSSRRTT 288
+ ++ L + H++ VIHRD+K +N+ + G G +KI D G + S +
Sbjct: 249 ILKNWCRQVLKGLYFLHTRTPPVIHRDLKCDNIFITGPTGSVKIGDLGLATLKNQSFAKS 428
Query: 289 LCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPF-EANTYQETYKRIS 342
+ GT +++ PEM E +DE VD+++ G+ E + P+ E + + YKR++
Sbjct: 429 VIGTPEFMAPEMYEEH-YDEAVDVYAFGMCMLEMASSEYPYSECSNAAQIYKRVT 590
>01966
Length = 1735
Score = 79.0 bits (193), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 42/135 (31%), Positives = 70/135 (51%), Gaps = 4/135 (2%)
Frame = -1
Query: 173 GVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEY--APLGTVYRELQKLSKFDE 230
GV RE+ + LRH NI+ L + R++L+ E+ L + + D
Sbjct: 1588 GVPSSAIREIAMLRELRHTNIVCLEDVIMEDERLFLVFEFLSMDLKMYIDKFPEGVVLDR 1409
Query: 231 QRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGW--SVHAPSSRRTT 288
+ +Y+ ++ +++CH +R++HRD+KP+NLL+ G +KIADFG + P T
Sbjct: 1408 RLVKSYVFQIVTGINFCHQRRIVHRDLKPQNLLINHTGAIKIADFGMARTFALPVRAYTH 1229
Query: 289 LCGTLDYLPPEMIEG 303
TL Y PE++ G
Sbjct: 1228 EVVTLWYRAPEILMG 1184
>19761
Length = 473
Score = 76.3 bits (186), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 40/142 (28%), Positives = 77/142 (54%), Gaps = 4/142 (2%)
Frame = -3
Query: 230 EQRTATYITELANALSYCHSKR--VIHRDIKPENLLLGSAGELKIADFGWS--VHAPSSR 285
E+ ++ + A+AL+Y H+ ++HRD+KP+N+ + G++++ D G + + P+
Sbjct: 426 ERLIVCWLMQTASALNYMHTHTPVILHRDLKPQNIYVTEKGDVRLGDLGLARKLTGPADF 247
Query: 286 RTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVE 345
T+ GT+ YL PE++ + ++ K D+WSLG + Y+ K E + + +
Sbjct: 246 ATSQVGTIMYLSPEILSQQPYNSKSDIWSLGCVFYDITGKKGSDEMGVMFLLVQVMGGRK 67
Query: 346 FTFPDFVTEGARDLISRLLKHN 367
PD ++ RD ISR+L +
Sbjct: 66 LPLPDHYSQEFRDTISRMLTKD 1
>19094
Length = 898
Score = 70.1 bits (170), Expect(2) = 6e-14, Method: Compositional matrix adjust.
Identities = 39/103 (37%), Positives = 57/103 (55%), Gaps = 2/103 (1%)
Frame = +1
Query: 230 EQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS--VHAPSSRRT 287
E+ AT + L Y HS+R IHRDIK N+LL + G K+ADFG + + ++R
Sbjct: 55 EREIATILYYTLKGL*YLHSRRKIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRN 234
Query: 288 TLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFE 330
T+ GT ++ PE+I+ +D D+WSLG+ E G E
Sbjct: 235 TVIGTPYWMAPEVIQEIGYDCVADIWSLGITALEMAEGNLHME 363
Score = 24.6 bits (52), Expect(2) = 6e-14, Method: Compositional matrix adjust.
Identities = 12/38 (31%), Positives = 19/38 (50%)
Frame = +3
Query: 346 FTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWI 383
F PD + D +S+ L NP R ++L+H +I
Sbjct: 417 FRQPDKWSTEFIDFVSKCLVKNPENRATAVDLLQHDFI 530
>26560
Length = 398
Score = 74.7 bits (182), Expect = 7e-14, Method: Composition-based stats.
Identities = 40/131 (30%), Positives = 67/131 (51%), Gaps = 1/131 (0%)
Frame = -1
Query: 218 VYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGW 277
++ L + F E+ Y E+ L + HS+ V++RD+KP N+LL G ++I+D G
Sbjct: 395 LHYHLSQHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGL 216
Query: 278 SVHAPSSRRTTLCGTLDYLPPE-MIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQE 336
+ R GT Y+ PE +++G+ +D D +S G + Y+ L G PF + +
Sbjct: 215 ACDFSKKRPHASVGTHGYMAPEVLMKGQSYDSSADWFSFGCMLYKLLKGHSPFR--QHNQ 42
Query: 337 TYKRISRVEFT 347
RI R+ T
Sbjct: 41 GQARIDRMTMT 9
>29581
Length = 1278
Score = 72.0 bits (175), Expect = 4e-13, Method: Compositional matrix adjust.
Identities = 63/235 (26%), Positives = 101/235 (42%), Gaps = 38/235 (16%)
Frame = -2
Query: 187 HLRHPNILRL----YGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELAN 242
+LRH NI++L G D+ ++L++EY + F E + + +L
Sbjct: 1187 NLRHQNIVQLQEVVVGKSLDS--LFLVMEYCEQDLASLLDNMPAPFSESQVKCIVLQLLK 1014
Query: 243 ALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVH--APSSRRTTLCGTLDYLPPEM 300
L Y H +IHRD+K NLL+ G +KIADFG + + P T TL Y PE+
Sbjct: 1013 GLRYLHEAFIIHRDLKVSNLLMTDKGCVKIADFGLARNYGKPQKPMTPKVVTLWYRAPEL 834
Query: 301 IEG-RMHDEKVDLWSLGVLCYEFLVGKPPFEANT-------------------------- 333
+ G + H +D+WS G + E L KP +
Sbjct: 833 LFGSKTHSTAIDMWSAGCILGELLGHKPLMPGRSDLQQIELIMELLGTPNDTIWPGFSQL 654
Query: 334 ---YQETYKR--ISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWI 383
Q T K+ + + TFP +++E L++ L ++P +R + LEH +
Sbjct: 653 PAFEQFTLKKQPYNNLRHTFP-WLSESGIRLLNGLFMYHPQKRATAEDCLEHSYF 492
>20152
Length = 445
Score = 68.9 bits (167), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 32/96 (33%), Positives = 50/96 (52%), Gaps = 1/96 (1%)
Frame = +1
Query: 298 PEMIEGRMHDE-KVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGA 356
PE++ G +D VD+WSLGV+ Y +VG+ PF+ ET I + P ++
Sbjct: 1 PEILLGDSYDAPAVDVWSLGVILYMLVVGEAPFQEANDSETLTMIMDCRYQIPPHISHKC 180
Query: 357 RDLISRLLKHNPSQRPMLREVLEHPWITANSSKPSN 392
+DLI ++L+ P R L +L HPW+ P+
Sbjct: 181 QDLIEKMLQREPVDRASLPHILAHPWLNDGDLTPTT 288
>27405
Length = 532
Score = 67.8 bits (164), Expect = 7e-12, Method: Compositional matrix adjust.
Identities = 47/175 (26%), Positives = 84/175 (48%), Gaps = 5/175 (2%)
Frame = -3
Query: 144 FGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLR----HPNILRLYGY 199
FG VY R+ + + A+K L K +++ G E E + S + P I+ +
Sbjct: 527 FGEVYGCRKADTGKMYAMKCLDKKRIKMKGGETLALNERIMLSLVSTGEGSPFIVCMTYA 348
Query: 200 FHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKP 259
F ++ IL+ G ++ L + F E+ Y E+ L + HS+ V++RD+KP
Sbjct: 347 FQTPEKLCFILDLMNGGDLHYHLSQHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKP 168
Query: 260 ENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPE-MIEGRMHDEKVDLW 313
N+LL G ++I+D G + + GT Y+ PE +++G+ +D D +
Sbjct: 167 ANILLDENGHVRISDLGLACDFSKKKPHASVGTHGYMAPEVLMKGQAYDSSADWF 3
>26711
Length = 405
Score = 65.9 bits (159), Expect = 3e-11, Method: Composition-based stats.
Identities = 39/132 (29%), Positives = 72/132 (54%), Gaps = 8/132 (6%)
Frame = -2
Query: 237 ITELANALSYCHSKRVIHRDIKPENLLLG--SAGELKIADFGWSVHAPSSRRTTLC-GTL 293
+ ++ + L + H++ V+H D+KP NLLL +++ DFG + + T L GT
Sbjct: 398 VKQVLDILQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARKLYPPQETFLNHGTP 219
Query: 294 DYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTF---PD 350
+ PE ++ + D+W +GVL Y L G+ PF+A++ E+ K+ +++F P
Sbjct: 218 GFTSPEALDVKPISTASDVWGVGVLAYILLSGQSPFQADSATESLKKTQTCDWSFDVCPS 39
Query: 351 F--VTEGARDLI 360
F +++ A+D I
Sbjct: 38 FSNMSQDAKDFI 3
>19301
Length = 712
Score = 65.1 bits (157), Expect = 5e-11, Method: Compositional matrix adjust.
Identities = 33/101 (32%), Positives = 56/101 (55%), Gaps = 2/101 (1%)
Frame = +2
Query: 180 REVEIQS--HLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYI 237
+E +I++ L HPNI+ G A +I+EY P G +Y L+ + +
Sbjct: 410 KETDIRNLRKLNHPNIISFKGVCTQAPCYCIIMEYCPYGQLYEVLRDGKEIPPALVLDWS 589
Query: 238 TELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS 278
++A+ ++Y HS ++IHRD+K N+L+ +KI+DFG S
Sbjct: 590 KQIASGMNYLHSHKIIHRDLKSPNVLVAKNDVVKISDFGTS 712
>38560
Length = 479
Score = 64.7 bits (156), Expect = 6e-11, Method: Compositional matrix adjust.
Identities = 33/111 (29%), Positives = 58/111 (52%), Gaps = 1/111 (0%)
Frame = -3
Query: 287 TTLCGTLDYLPPEMIEGRMH-DEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVE 345
TT CG+ Y PE+I G + + D+WS+GVL Y L G PF+ ++ + +
Sbjct: 411 TTCCGSPAYAAPELISGLEYLGSEADIWSMGVLLYALLCGYLPFDDEKXSHL*QKNQKRK 232
Query: 346 FTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQNK 396
P++++E L+ +L+ +PS R +R +L+H W+ + P +K
Sbjct: 231 DEVPEWLSEDTTKLLEGMLQTDPSHRITIRRLLDHHWLNQGFNVPVEWASK 79
>14477
Length = 493
Score = 63.9 bits (154), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 44/142 (30%), Positives = 73/142 (51%), Gaps = 2/142 (1%)
Frame = -1
Query: 139 LGKGKFGNVY--LAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRL 196
LG G FG+V + R + +A+KVL A L+ + V+ +L +E E+ + H +I+RL
Sbjct: 466 LGAGNFGSVMKGVCRLDDREIPVAIKVLKNADLDPS-VQSELIKEAEVMKKMDHMHIVRL 290
Query: 197 YGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRD 256
G T + L+LE A LG + + L K + +++ + Y + + +HRD
Sbjct: 289 IGLCEGET-MMLVLELAKLGPLNKFLPKNKHLPLWNILELMWQVSQGMEYLEANKFVHRD 113
Query: 257 IKPENLLLGSAGELKIADFGWS 278
+ N+LL KI+DFG S
Sbjct: 112 LAARNILLCDEHFAKISDFGMS 47
>04852
Length = 1462
Score = 63.9 bits (154), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 40/151 (26%), Positives = 75/151 (49%), Gaps = 5/151 (3%)
Frame = +1
Query: 235 TYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTL- 293
+Y ++A + + S++ IHRD+ N+L+ LKIADFG S ++ + G L
Sbjct: 337 SYAFQIARGMEFLASRKCIHRDLAARNVLVTEEHVLKIADFGLSRTGDYYKKRS-GGRLP 513
Query: 294 -DYLPPEMIEGRMHDEKVDLWSLGVLCYE-FLVGKPPFEANTYQETYKRISRVEFTF--P 349
++ PE + + K D+WS GV+ +E F +G P+ + +E Y ++ + P
Sbjct: 514 VKWMAPEALFDMRYTTKSDVWSFGVVLWEIFSLGGMPYASIPNEELYSKLLDDAYRMPRP 693
Query: 350 DFVTEGARDLISRLLKHNPSQRPMLREVLEH 380
+ + ++ R + PS RP +++ H
Sbjct: 694 ELASGNLYAIMERCWLNRPSDRPEFSQLVGH 786
>06358
Length = 1517
Score = 63.5 bits (153), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 65/273 (23%), Positives = 121/273 (44%), Gaps = 40/273 (14%)
Frame = +3
Query: 140 GKGKFGNVYLAREKQSK-----FILALKVLFK-AQLEKAGVEHQLRREVEIQSHLRHPNI 193
G G V+ A +K +K F+ K + + ++ ++ + LR V+ + LRHP I
Sbjct: 33 GPGLLWKVFAASKKSTKEEASVFVFEKKSVDRYSRRDREAIVEVLRVGVQQLTKLRHPKI 212
Query: 194 LRLYGYFHD-------------ATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITEL 240
L + + A+ ++ + + + TV +ELQ +D + + ++
Sbjct: 213 LAVINPLEESRETLAFATEPVFASLANVLGDLSSIXTVPKELQDYQLYDVE-IKHGLLQV 389
Query: 241 ANALSYCHSK-RVIHRDIKPENLLLGSAGELKIADFGWSVHA--PSSR---------RTT 288
AL + H+ +++HR++ PE ++L G K+A + + V + P S R+
Sbjct: 390 TEALGFLHNDAKMMHRNVCPEAIMLTKLGSWKLAGYEFCVRSSDPQSTDPSYPFYEWRSD 569
Query: 289 LCGT----LDYLPPEMIEGRMHDEKVDLWSLGVLCYE-FLVGKPPFEAN----TYQETYK 339
+ LD++ PE + D++SLG+L Y F GKP FE N ++ +
Sbjct: 570 IAPVTQPHLDFMAPEYVLTMQCGTGSDMFSLGLLVYSVFAKGKPLFECNGELSAFKSNAE 749
Query: 340 RISRVEFTFPDFVTEGARDLISRLLKHNPSQRP 372
+ + + V E RD + LL P+ RP
Sbjct: 750 ELRHMRVSLLGVVPEDLRDHVKLLLNIEPAVRP 848
>04138
Length = 800
Score = 63.5 bits (153), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 51/177 (28%), Positives = 72/177 (40%), Gaps = 40/177 (22%)
Frame = +1
Query: 244 LSYCHSKRVIHRDIKPENLLLGSAGELKIADFG----WSVHAPS-SRRTTLCGTLDYLPP 298
L Y H +++HRD+K N+L+ G LK+ADFG +SV+ +R T TL Y PP
Sbjct: 52 LYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRPP 231
Query: 299 EMIEG-RMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGAR 357
E++ G R + +D W G + E P + T Q I+++ + V G
Sbjct: 232 ELLLGDRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQNQLTLITQLCGSITPEVWPGVT 411
Query: 358 ----------------------------------DLISRLLKHNPSQRPMLREVLEH 380
DL RLLK +PSQR E L H
Sbjct: 412 QLSMYHQIKGALAAGRKNIIRDRFARILKDPYGLDLFERLLKMDPSQRISADEALNH 582
>21808
Length = 1011
Score = 63.2 bits (152), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 43/166 (25%), Positives = 73/166 (43%), Gaps = 5/166 (3%)
Frame = +1
Query: 181 EVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYI-TE 239
E +I LRHP +++LY +++I E G++ LQ + + I +
Sbjct: 82 EAQIMKKLRHPKLIQLYAVCTQDDPIFIITELMKNGSLLEFLQGKGRVLKLPALIDIGAQ 261
Query: 240 LANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGT---LDYL 296
+A ++Y S+ IHRD+ N+L+ +KIADFG + G + +
Sbjct: 262 IACGMAYLESQNYIHRDLAARNILVSDNNTVKIADFGLARVIKEDEYEARVGARFPIKWT 441
Query: 297 PPEMIEGRMHDEKVDLWSLGVLCYEFLV-GKPPFEANTYQETYKRI 341
PE K D+WS G+L E + G+ P+ T E ++
Sbjct: 442 APEAANYNRFTIKSDVWSFGILLTETVTYGRVPYPGMTNAEVLHQV 579
>00715
Length = 1788
Score = 61.6 bits (148), Expect = 5e-10, Method: Compositional matrix adjust.
Identities = 47/177 (26%), Positives = 76/177 (42%), Gaps = 33/177 (18%)
Frame = +1
Query: 188 LRHPNILRLYGY-----FHDATRVYLILEYAP---LGTVYRELQKLSKFDEQRTATYITE 239
LRH N++ + G F D +L +EY L T+ + Q+ D + +
Sbjct: 97 LRHVNVVSILGATSLHRFEDGA--WLAMEYVGPLNLQTILNDHQQ--DIDSSMRLSLALQ 264
Query: 240 LANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVH------------------- 280
+A L Y HS ++H D+KP N LL +L+IADFG H
Sbjct: 265 MARGLHYLHSINIVHLDLKPANCLLTRDLKLRIADFG-CCHQLTPTGLDMGEREGGMAGN 441
Query: 281 ------APSSRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEA 331
+ + L GTL Y PE+++G + D++SLG+ ++ + P+E
Sbjct: 442 ELELTPVQGAWKNELAGTLAYRAPELLKGLQPSVRSDVYSLGITLWQMCTRQGPYEG 612
>14116
Length = 1017
Score = 61.2 bits (147), Expect = 6e-10, Method: Compositional matrix adjust.
Identities = 56/217 (25%), Positives = 96/217 (44%), Gaps = 24/217 (11%)
Frame = -1
Query: 131 EDFEIGRPLGKGKFGNV---YLAR-EKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQS 186
E +G +GKG FG V +L E++ ++A+K L RE+E+QS
Sbjct: 636 EFLTMGEEIGKGNFGCVKRGFLTLPEQKGDILVAVKTLHNNN----------PREIELQS 487
Query: 187 HLR---------HPNILRLYGY---FHDATRVYL-ILEYAPLGTVYRELQKLSKFDEQRT 233
L+ H N+L L G D V L +++ L T R+ Q +
Sbjct: 486 FLQEALIMKDFHHSNVLTLIGICLNLDDMPLVVLPFMKHGDLLTYIRDDQHQPTIKD--L 313
Query: 234 ATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS-------VHAPSSRR 286
Y ++A + Y + +HRD+ N +L +K+ADFG + ++ +++
Sbjct: 312 IMYGVDIARGMDYLAGLKFVHRDLAARNCMLDEDFHVKVADFGLARDIYEKEYYSSENKK 133
Query: 287 TTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFL 323
L + ++ E +E +D K D+WS GV+ +E L
Sbjct: 132 AKL--PVKWMALESLEKGNYDSKTDVWSYGVVLWELL 28
>28157
Length = 400
Score = 61.2 bits (147), Expect = 8e-10, Method: Compositional matrix adjust.
Identities = 39/104 (37%), Positives = 57/104 (54%), Gaps = 7/104 (6%)
Frame = +3
Query: 180 REVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLS---KFDEQRTATY 236
+E++ S + HPNI+ LYG D V L++EYA G++Y L ++ +
Sbjct: 57 QELKQLSRVSHPNIVCLYGACRDHP-VCLVMEYAEGGSLYNVLHGSGPQPQYTAAHAMNW 233
Query: 237 ITELANALSYCHS---KRVIHRDIKPENLLLGSAG-ELKIADFG 276
+ + A + Y H K +IHRD+KP NLLL G +LKI DFG
Sbjct: 234 LLQCALGVEYLHGMKPKALIHRDLKPPNLLLIQCGTKLKICDFG 365
>12672
Length = 773
Score = 60.8 bits (146), Expect = 9e-10, Method: Compositional matrix adjust.
Identities = 45/161 (27%), Positives = 69/161 (42%), Gaps = 24/161 (14%)
Frame = +3
Query: 241 ANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTT------LCGTLD 294
A+ + Y + +HRDIK N+LL S K+ DF V APS T + GT
Sbjct: 21 ASGIQYLNDNGHVHRDIKTANILLDSEYTAKVGDFATVVSAPSGEGKTVQNASVVIGTAA 200
Query: 295 YLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTY------------------QE 336
YL PE I + K+D +S GV+ E + G A Y +E
Sbjct: 201 YLAPEAIHFDVS-TKLDSYSFGVVLLEVITG---LVAQDYSREERTLSSHIMENVEEPEE 368
Query: 337 TYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREV 377
+ + + T+PD + D+ R L + QRP ++++
Sbjct: 369 IHDFVDQSAGTWPDGAVDKLYDISMRCLNLSKKQRPNVKDI 491
>07940
Length = 1336
Score = 60.8 bits (146), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 36/100 (36%), Positives = 54/100 (54%), Gaps = 5/100 (5%)
Frame = -3
Query: 235 TYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS--VHAPSSRRTTLCGT 292
+Y ++A + Y SK+ IHRD+ N+L+ LKIADFG + + R T G
Sbjct: 335 SYAYQVARGMEYLASKQCIHRDLAARNVLVAEEYVLKIADFGLTRNLQQFDYYRKTTDGR 156
Query: 293 L--DYLPPEMIEGRMHDEKVDLWSLGVLCYE-FLVGKPPF 329
L ++ PE + R + K D+WS GVL +E F +G P+
Sbjct: 155 LPVKWMAPEALFDRKYTSKSDVWSYGVLLWEIFTLGGNPY 36
Score = 34.3 bits (77), Expect = 0.088, Method: Compositional matrix adjust.
Identities = 28/95 (29%), Positives = 49/95 (51%), Gaps = 7/95 (7%)
Frame = -3
Query: 131 EDFEIGRPLGKGKFGNVYLAREKQSKF------ILALKVLFKAQLEKAGVEHQLRREVEI 184
E +G LG+G FG V + E F +A+K+L + ++ ++ L RE+E+
Sbjct: 842 ERLVLGDRLGEGAFGLV-MKGEAMGIFKDNNSVTVAVKMLKEDATDREMMD--LIREMEM 672
Query: 185 QSHL-RHPNILRLYGYFHDATRVYLILEYAPLGTV 218
+ +H NI+ L G +Y+I+E+AP G +
Sbjct: 671 MKVIGKHKNIINLLGCCTQRGALYVIVEFAPHGNL 567
>03508
Length = 1463
Score = 60.8 bits (146), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 31/109 (28%), Positives = 57/109 (52%), Gaps = 3/109 (2%)
Frame = +1
Query: 223 QKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAG-ELKIADFGWS-VH 280
Q F + Y+ EL AL +CHS ++HRD+KP N+++ +L++ D+G + +
Sbjct: 847 QLYQTFTDYDIRFYLYELMKALDFCHSMGIMHRDVKPHNVMIDHENKKLRLIDWGLAEFY 1026
Query: 281 APSSRRTTLCGTLDYLPPE-MIEGRMHDEKVDLWSLGVLCYEFLVGKPP 328
P + + PE +++ +M+D +D+WSLG + + K P
Sbjct: 1027HPGMEYNVRVASRYFKGPELLLDYQMYDYSLDMWSLGCMFASMIFRKEP 1173
>26009
Length = 886
Score = 40.8 bits (94), Expect(2) = 3e-09, Method: Compositional matrix adjust.
Identities = 17/49 (34%), Positives = 30/49 (61%)
Frame = +3
Query: 216 GTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLL 264
GT ++ + + + +L +AL + HSK+++HRDIKPEN+L+
Sbjct: 666 GTCLTPSRRNKACGSREAKSVMKQLVSALDFMHSKQLVHRDIKPENVLI 812
Score = 38.1 bits (87), Expect(2) = 3e-09, Method: Compositional matrix adjust.
Identities = 26/91 (28%), Positives = 47/91 (51%), Gaps = 2/91 (2%)
Frame = +2
Query: 131 EDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLR- 189
E +++ + LG+G +G V LAR + + +ALK+L K+ + + +RE ++ L
Sbjct: 416 EHYDVCKELGRGTYGKVVLARCRHTGTQVALKLLPKSCTKL----REFQREFQLSYFLSP 583
Query: 190 HPNILRLYGY-FHDATRVYLILEYAPLGTVY 219
H NI+ Y F + E+A LG ++
Sbjct: 584 HANIIDTYNVAFQTRSSYVFAQEHAVLGDLF 676
>12786
Length = 460
Score = 58.9 bits (141), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 37/127 (29%), Positives = 54/127 (42%), Gaps = 24/127 (18%)
Frame = -3
Query: 228 FDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRT 287
D Y E+ A+ H++ VIH D+KP N +L AG LK+ DFG + + +
Sbjct: 419 LDRMMIKFYWREMLRAVKALHNEGVIHSDLKPANFML-VAGNLKLIDFGIANTLQQDKTS 243
Query: 288 TL----CGTLDYLPPEMIEGRMHDE--------------------KVDLWSLGVLCYEFL 323
L GT Y+ PE I D + D+WSLG + Y +
Sbjct: 242 VLKDSRVGTPSYMSPEAIMAACDDSADDSMEEDGHRTKPKYKVGVRSDVWSLGCILYNMV 63
Query: 324 VGKPPFE 330
G+ PF+
Sbjct: 62 YGRTPFQ 42
>18663
Length = 600
Score = 57.8 bits (138), Expect = 7e-09, Method: Compositional matrix adjust.
Identities = 32/112 (28%), Positives = 52/112 (46%), Gaps = 15/112 (13%)
Frame = +2
Query: 287 TTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEA---------NTYQET 337
+T CGT +Y+ PE++ G + VD W+LGVL YE L G+ PF+ NT
Sbjct: 2 STFCGTPNYIAPEILRGEDYGFSVDWWALGVLLYEMLAGRSPFDIAGASENPDQNTEDYL 181
Query: 338 YKRISRVEFTFPDFVTEGARDLISRLLKHNPSQR------PMLREVLEHPWI 383
++ I P ++ A ++ L NP+ R +++ HP+
Sbjct: 182 FQVILEKTIRIPRSLSVKAASVLKGFLNKNPADRLGCHRESAFMDIVNHPFF 337
>28638
Length = 1458
Score = 55.8 bits (133), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 41/132 (31%), Positives = 60/132 (45%), Gaps = 5/132 (3%)
Frame = -1
Query: 203 ATRVYLILEYAP-LGTVYRELQKLSKFDEQRTATYITELANALSYCHS--KRVIHRDIKP 259
AT L +P + T Q L T + +L AL + + +IH D+KP
Sbjct: 924 ATTCVWCLSCSPTISTTCYATQTLEGVSLNLTRKFAQQLCTALLFLATPEMNIIHCDLKP 745
Query: 260 ENLLLGSA--GELKIADFGWSVHAPSSRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGV 317
EN+LL + +KI DFG S R + Y PE++ G +D +D+WSLG
Sbjct: 744 ENILLCNPKRSAIKIVDFGSSCQL-GQRIYQYIQSRFYRSPEVLLGVPYDLAIDMWSLGC 568
Query: 318 LCYEFLVGKPPF 329
+ E G+PP
Sbjct: 567 ILVEMHTGEPPL 532
>02638
Length = 1490
Score = 53.1 bits (126), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 27/104 (25%), Positives = 52/104 (50%), Gaps = 5/104 (4%)
Frame = +1
Query: 289 LCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFT- 347
L GT+ ++ PE++ G + D+WS+G + E +PP+ ++ I ++ +
Sbjct: 16 LLGTIAFMAPEVLRGESYGRACDVWSVGCVMIEMCTCRPPWNSHDISNHLALIFKIASSV 195
Query: 348 ----FPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANS 387
P+ ++ RDL+ R L+ + RP +++L HP T S
Sbjct: 196 DPPPIPENMSPPVRDLMLRCLEQDSDFRPSAKDLLMHPLFTKYS 327
>11185
Length = 473
Score = 52.4 bits (124), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 30/110 (27%), Positives = 48/110 (43%), Gaps = 24/110 (21%)
Frame = +1
Query: 240 LANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFG----------------------W 277
L L Y HS ++ D++P +LL ++G LK ADFG W
Sbjct: 28 LVTGLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQW 207
Query: 278 SVHAPSS--RRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVG 325
++ + ++ G+ Y+ PE+ +G DLW+LG + YE G
Sbjct: 208 NIQSAEEMMKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSG 357
>25019
Length = 730
Score = 52.4 bits (124), Expect = 4e-07, Method: Compositional matrix adjust.
Identities = 25/59 (42%), Positives = 35/59 (59%), Gaps = 2/59 (3%)
Frame = +3
Query: 260 ENLLLGSAGELKIADFGWSVHAPSSRRTT--LCGTLDYLPPEMIEGRMHDEKVDLWSLG 316
EN+LL G +K+ DFG A + R T CGT++Y+ PE++ H + VD WSLG
Sbjct: 261 ENVLLDKDGHVKLTDFGLCKEAITGTRVTHTFCGTIEYMAPEILTRTGHGKAVDWWSLG 437
>29590
Length = 320
Score = 38.9 bits (89), Expect(2) = 1e-06, Method: Composition-based stats.
Identities = 17/41 (41%), Positives = 24/41 (58%)
Frame = +3
Query: 289 LCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPF 329
+ GT DY+ PE+++ + D+WSLGVL Y L PF
Sbjct: 54 IIGTPDYVAPEVLDYEPLSIQTDMWSLGVLSYVMLTACSPF 176
Score = 31.2 bits (69), Expect(2) = 1e-06, Method: Composition-based stats.
Identities = 16/41 (39%), Positives = 24/41 (58%), Gaps = 4/41 (9%)
Frame = +2
Query: 335 QETYKRISRVEFTFPD----FVTEGARDLISRLLKHNPSQR 371
QET+ IS+V+ FPD ++ A+D I +LL +P R
Sbjct: 191 QETFCNISQVKLDFPDDLFSHISPHAKDFIKKLLVKDPRHR 313
>27274
Length = 396
Score = 49.7 bits (117), Expect = 2e-06, Method: Composition-based stats.
Identities = 30/97 (30%), Positives = 45/97 (46%), Gaps = 12/97 (12%)
Frame = -1
Query: 299 EMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEAN------------TYQETYKRISRVEF 346
E++ G+ H VD+WSLG+L +E L G PFE Y + + SR
Sbjct: 375 ELLRGQQHGPTVDMWSLGILLHELLSGHVPFEPERGSRQMARNMMAVYAQIIRGSSRDVC 196
Query: 347 TFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWI 383
T GA D + RL++ ++R ++ HPWI
Sbjct: 195 DGLALSTHGA-DFLRRLVQLEDTKRLTSQQAFSHPWI 88
>31120
Length = 439
Score = 48.9 bits (115), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 33/99 (33%), Positives = 53/99 (53%), Gaps = 6/99 (6%)
Frame = +1
Query: 299 EMIEGRMHDEKV-DLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTF----PDFVT 353
E++ G +D K+ D WSLGV+ + L GK PF+ + + + +++F D V+
Sbjct: 1 EVVCGVPYDPKMADAWSLGVILFIMLNGKMPFDDSNLNKLLEDQRSKKYSFRRKLQDLVS 180
Query: 354 EGARDLISRLLKHNPSQRPMLREVLEHPWI-TANSSKPS 391
AR +S LL+ N + R L EVL W+ T + +PS
Sbjct: 181 PNARSTVSVLLEPNSAMRWDLNEVLNCQWLQTIDEPRPS 297
>37602
Length = 804
Score = 48.5 bits (114), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 32/99 (32%), Positives = 46/99 (46%), Gaps = 3/99 (3%)
Frame = -1
Query: 189 RHPNILRLYGYFHDATR---VYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALS 245
R NI GYF R +++ +EY G++ E + A E L
Sbjct: 354 RIVNIQTFVGYFDSYLRREKLWIAMEYCGGGSMQDIYHVTGPLTEPQIAFVCRETLKGLH 175
Query: 246 YCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSS 284
Y H + +HRDIK N+LL G++K+ADF W V + S
Sbjct: 174 YLHRRGKMHRDIKGANILLTEEGDVKLADF-WRVSSNHS 61
>07833
Length = 1504
Score = 48.1 bits (113), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 45/213 (21%), Positives = 88/213 (41%), Gaps = 21/213 (9%)
Frame = -3
Query: 188 LRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKF--DEQRTATYITELANALS 245
HPN+L + + + LI ++ P G++Y L S D+ ++ + ++A +
Sbjct: 1448 FNHPNVLPVLACCNQPPNLVLISQFMPFGSLYNTLHGESGIVVDQNQSLRFAMDIARGME 1269
Query: 246 YCHSKRVIHRDIKPE--NLLLGS---------AGELKIADFGWSVHAPSSRRTTLCGTLD 294
+ HS ++P N LL S + +AD+ +S H +
Sbjct: 1268 FLHS-------MEPTIPNFLLTSKHVMIDEDLTARINMADYCFSFHEKGKVYSP-----A 1125
Query: 295 YLPPEMIEGRMHD---EKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISR--VEFTFP 349
++ PE ++ R D D+WS +L +E + PF + E +++ + + P
Sbjct: 1124 WMAPEALQRRPDDINTRAADMWSFAILMWELETREVPFAELSSMEVGMKVALEGLRISIP 945
Query: 350 DFVTEGARDLISRLLKHNPSQRP---MLREVLE 379
++ LI + P +RP M+ +LE
Sbjct: 944 PGISLHMSRLIKICMNEEPGKRPRFDMIIPILE 846
>32000
Length = 644
Score = 48.1 bits (113), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 39/148 (26%), Positives = 63/148 (42%), Gaps = 31/148 (20%)
Frame = -1
Query: 267 AGELKIADFGWS--VHAPSSRRTTLCGTLDYLPPEMIEG-RMHDEKVDLWSLGVLCYEFL 323
++KIADFG + P T TL Y PE++ G R + VD+WSLG + E +
Sbjct: 581 TAKMKIADFGLARVFGLPVRTYTHEVITLWYRAPEILLGCRFYSVPVDIWSLGCIFVEMM 402
Query: 324 VGKPPFEANTYQETYKRISRVEFT-----------FPDF-----------------VTEG 355
+ F ++ + RI R T PD+ +++
Sbjct: 401 TRRALFPGDSEIDQLYRIFRTLGTPDEKVWPGVSKLPDYKPTFPKWPLKNLETVVSLSKV 222
Query: 356 ARDLISRLLKHNPSQRPMLREVLEHPWI 383
DL+ R+L +NP++R R + HP+
Sbjct: 221 GLDLLKRMLTYNPNRRISARSAMRHPYF 138
>07291
Length = 833
Score = 47.8 bits (112), Expect = 8e-06, Method: Compositional matrix adjust.
Identities = 25/97 (25%), Positives = 50/97 (51%), Gaps = 6/97 (6%)
Frame = +1
Query: 239 ELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHA-PSSRRTT----LCGTL 293
++A+ ++Y +V+HR++ N ++ G L+++D+G + P S T +
Sbjct: 73 QIADGMAYLQEVKVVHRNLAARNCIVTEDGRLQLSDYGVTGSLFPQSYYTADDSPARDLV 252
Query: 294 DYLPPEMIEGRMHDEKVDLWSLGVLCYEFLV-GKPPF 329
++ PE I+ K D+W+ GV+ +E L G P+
Sbjct: 253 KWMAPETIDNFHFSSKSDVWAFGVVLWELLTRGITPY 363
>01106
Length = 878
Score = 46.6 bits (109), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 46/147 (31%), Positives = 70/147 (47%), Gaps = 15/147 (10%)
Frame = +3
Query: 133 FEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQ--LEKAGVEHQLRREVEIQSHLRH 190
+ + R LG G F V+L + K +ALKV+ AQ E A E +L + V +S +
Sbjct: 324 YHVIRKLGWGHFSTVWLCWDLTCKRFVALKVVKSAQHYTETALDEVKLLKCVR-ESDVAD 500
Query: 191 PNILRLYGYFHD-------ATRVYLILEYAPLGTVYRELQKLSKFDEQRTATY-----IT 238
P + D T V ++ E LG Y L+ + + + Q + I
Sbjct: 501 PARAKCVQLLDDFKISGVNGTHVAMVFEV--LG--YNLLKLIIRSNYQGIPIHNVKLIIR 668
Query: 239 ELANALSYCHSK-RVIHRDIKPENLLL 264
++ LSY H+K R+IH DIKPEN+L+
Sbjct: 669 QVLEGLSYMHAKCRIIHTDIKPENILI 749
>18481
Length = 437
Score = 44.7 bits (104), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 38/119 (31%), Positives = 57/119 (47%), Gaps = 7/119 (5%)
Frame = -1
Query: 167 AQLEKAGVEHQL-RREVEIQSHL-RHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQK 224
++E V+HQL E ++ + RHP + +Y Y + L++E LG EL
Sbjct: 395 VKIEAIDVKHQLLHYEAKVYEQIGRHPGLPTMYHYGTEKHFNALVME--LLGPSLEELFV 222
Query: 225 LSK--FDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLG---SAGELKIADFGWS 278
+ K F + +L + L + H K IHRD+KP+N L+G L I DFG S
Sbjct: 221 ICKRRFTLKTILMVSDQLLSRLEFIHQKCFIHRDLKPDNFLMGLGRHCHRLYIIDFGLS 45
>32957
Length = 645
Score = 44.7 bits (104), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 20/60 (33%), Positives = 32/60 (53%)
Frame = +3
Query: 275 FGWSVHAPSSRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTY 334
F V R T CGT +Y+ PE+ E + + ++VD W LG+L +E L + ++ Y
Sbjct: 3 FALCVEKSGGRTRTFCGTREYMAPEVHERKEYGKEVDWWGLGILLHELLAAQIKKHSSCY 182
>31489
Length = 329
Score = 43.9 bits (102), Expect = 1e-04, Method: Composition-based stats.
Identities = 23/88 (26%), Positives = 43/88 (48%), Gaps = 6/88 (6%)
Frame = +3
Query: 182 VEIQSHLRHPNI------LRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTAT 235
++I H +H NI L+ +HD ++++ + ++R + E+
Sbjct: 3 IKILKHFKHDNIISIREILKPKDSYHDFKDIHVVFDLME-SDLHRIIYSDQPLTEEHIRY 179
Query: 236 YITELANALSYCHSKRVIHRDIKPENLL 263
++ ++ L Y HS V+HRD+KP NLL
Sbjct: 180 FLYQILRGLKYIHSANVVHRDLKPSNLL 263
>16708
Length = 1397
Score = 43.9 bits (102), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 64/266 (24%), Positives = 100/266 (37%), Gaps = 33/266 (12%)
Frame = -1
Query: 139 LGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNIL-RLY 197
LGKG FG VY AR L KA L+ + + H EVE + L +++
Sbjct: 1379 LGKGVFGKVYEAR--------LLSTHEKAALKTSILCHHSLDEVEALGRIEGGFYLAQMF 1224
Query: 198 GY------FHDATRVYLILEYAPLGTVYRELQK----LSKFDEQRTATYITELANALSYC 247
G F + E PL VY + + + + AL +
Sbjct: 1223 GAWVTCLPFPKMNILLHFYEMGPLCNVYAHYKNKEMPIRWSNPAMVCCIAGQXVCALEHI 1044
Query: 248 HSKRVIHRDIKPENLLLGSAGELKIADFG----WSVH-APSSRRTTLCG---TLDYLPPE 299
H V+H D+K +N+L+ + G K+ D+G + V+ AP+ ++ C T PP
Sbjct: 1043 HELGVVHMDVKADNVLVDAHGNCKLTDYGIAQLYKVYPAPTETHSSGCTNKRTFYTRPPA 864
Query: 300 -MIEGRMHDEKVD------------LWSL-GVLCYEFLVGKPPFEANTYQETYKRISRVE 345
M E+ D LW+L G + V +PP + + R E
Sbjct: 863 TMTPSERFSEEGDGIGTDYFRLGQMLWTLTGAVLLHVWVSRPPKLPD-----WCRTPESE 699
Query: 346 FTFPDFVTEGARDLISRLLKHNPSQR 371
+ G D I +L +P+ R
Sbjct: 698 LS-------GMSDFIEKLCHGDPNMR 642
>17253
Length = 483
Score = 43.9 bits (102), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 27/112 (24%), Positives = 53/112 (47%), Gaps = 13/112 (11%)
Frame = -1
Query: 180 REVEIQSHL-RHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQK--------LSKFDE 230
RE+ I L RHPN++ G + +++E+ G + L+K L+
Sbjct: 402 RELSIMRKLPRHPNVVSFMGCCTMSDPALILMEFCCHGDLLSFLRKRRPDRTVFLTSTAN 223
Query: 231 QRTA----TYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS 278
TA ++ +A +++ + +++HRD+ N+L+ K++DFG S
Sbjct: 222 DLTARDFFSFALHVARGMAHVANNKIVHRDVAARNVLISERNVCKVSDFGLS 67
>20640
Length = 1492
Score = 43.5 bits (101), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 38/144 (26%), Positives = 65/144 (45%), Gaps = 5/144 (3%)
Frame = +1
Query: 253 IHRDIKPENLLLGSAGELKIADFGW--SVHAPSSRRTTLCGT--LDYLPPEMIEGRMHDE 308
+HRD+ N L+G +KI+DFG SVH+ R + + ++P E I
Sbjct: 10 VHRDLATRNCLVGHDLVVKISDFGLARSVHSVDYYRGSEHDAIPIRWMPLEAILYNKFST 189
Query: 309 KVDLWSLGVLCYE-FLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHN 367
+ D+WS GV+ +E F P+ T++E + FV EG ++L
Sbjct: 190 QSDVWSFGVVLWEIFAFALQPYYGLTHEEVVR-----------FVKEG------KVLACP 318
Query: 368 PSQRPMLREVLEHPWITANSSKPS 391
P + E+++ W +++PS
Sbjct: 319 ERTPPPMYELMKQCWHRRPATRPS 390
>07836
Length = 1478
Score = 42.7 bits (99), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 49/195 (25%), Positives = 85/195 (43%), Gaps = 31/195 (15%)
Frame = -1
Query: 159 LALKVLFKAQLEKAGVEHQLRREVEIQSH--LRHPNILRLYGY----FHDATRVYLILEY 212
+A+K+ F + E RE E+ LRH NIL T+++LI +Y
Sbjct: 1469 VAVKIFFTTE------EASWFRETELYQTVLLRHENILGFIAADIKGTGSWTQLFLITDY 1308
Query: 213 APLGTVYRELQKLSK-FDEQRTATYITELANALSYCHSK--------RVIHRDIKPENLL 263
G+++ L LS+ D L++ H + + HRDIK +N+L
Sbjct: 1307 HENGSLHDYL--LSRVLDSSEMLALAHSAICGLAHLHIEIFGTRGKPAIAHRDIKSKNIL 1134
Query: 264 LGSAGELKIADFGWSVH----------APSSRRTTLCGTLDYLPPEMIEGRMHD------ 307
+ G IAD G +V AP+ R+ GT Y+ PE++E ++
Sbjct: 1133 VKKNGTCCIADLGLAVRYISESNEVDVAPNPRQ----GTKRYMAPEVLEMLLNVKNFDAF 966
Query: 308 EKVDLWSLGVLCYEF 322
++ D+++ G++ +E
Sbjct: 965 KQADMYAFGLVMWEI 921
>20559
Length = 430
Score = 39.7 bits (91), Expect(2) = 3e-04, Method: Compositional matrix adjust.
Identities = 22/81 (27%), Positives = 45/81 (55%)
Frame = -2
Query: 130 LEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLR 189
++ +E +G+G +G V+ A+ +++ I+ALK + + + GV RE+ + L+
Sbjct: 378 MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRV-RLDDDDEGVPSSALREICLLKELK 202
Query: 190 HPNILRLYGYFHDATRVYLIL 210
H NI+RL+ H ++ L+
Sbjct: 201 HRNIVRLHDVLHSERKLTLVF 139
Score = 21.9 bits (45), Expect(2) = 3e-04, Method: Compositional matrix adjust.
Identities = 7/12 (58%), Positives = 9/12 (75%)
Frame = -1
Query: 244 LSYCHSKRVIHR 255
L +CHS V+HR
Sbjct: 37 LVFCHSNNVLHR 2
>17300
Length = 480
Score = 42.0 bits (97), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 29/98 (29%), Positives = 46/98 (46%), Gaps = 7/98 (7%)
Frame = +1
Query: 253 IHRDIKPENLLLGSAGELKIADFGWSVHAPSSRR----TTLCGTL--DYLPPEMIEGRMH 306
+HRD+ N+L+ K+ADFG S S TT G + + PE I R
Sbjct: 40 VHRDLAARNILVNEILVCKVADFGLSREIESDTTEGAYTTKGGKIPVRWTAPEAIAYRKF 219
Query: 307 DEKVDLWSLGVLCYEFL-VGKPPFEANTYQETYKRISR 343
D+WS GV+ +E + G+ P+ + Q+ K + +
Sbjct: 220 TSASDVWSFGVVMWEVMSYGERPYWNWSNQDVIKAVEK 333
>11404
Length = 563
Score = 40.8 bits (94), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 42/150 (28%), Positives = 71/150 (47%), Gaps = 12/150 (8%)
Frame = +1
Query: 127 QWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKV-------LFKAQLEKAGVEHQLR 179
+WA + +EI +GKG FG V A + +A+K+ L +AQ+E +E R
Sbjct: 130 KWA-DRYEIDSLIGKGSFGQVVKAYDHTDNEQVAIKIIKNKKPFLNQAQIEVKLLEMMNR 306
Query: 180 REVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKF---DEQRTATY 236
+ + + + I+RL +F R +L L + L +L + + F T +
Sbjct: 307 HDTDNKYY-----IVRLKRHF--MFRSHLCLVFELLSYNLYDLLRNTNFRGVSLNLTRKF 465
Query: 237 ITELANALSYCHS--KRVIHRDIKPENLLL 264
+L AL + + +IH D+KPEN+LL
Sbjct: 466 AQQLCTALLFLATPEMSIIHCDLKPENILL 555
>21210
Length = 518
Score = 40.4 bits (93), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 27/106 (25%), Positives = 49/106 (46%), Gaps = 13/106 (12%)
Frame = +3
Query: 291 GTLDYLPPEMIEGRM----HDEKVDLWSLGVLCYEFLVGKPPFE--ANTYQETYKRISRV 344
G Y+ PE I+ R +D + D+WSLG+ E G+ P+ + + + + + V
Sbjct: 6 GCRPYMAPERIDPRASSHGYDVRSDVWSLGITLMELATGRFPYRKWVSIFDQLQQVVRGV 185
Query: 345 EFTFP-------DFVTEGARDLISRLLKHNPSQRPMLREVLEHPWI 383
P DFV + +++ L + QRP ++L HP++
Sbjct: 186 APCLPHDGAFSHDFV-----NFVNKCLTKDEKQRPKYNKLLAHPFV 308
>21418
Length = 831
Score = 39.7 bits (91), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 20/56 (35%), Positives = 32/56 (57%), Gaps = 4/56 (7%)
Frame = +2
Query: 339 KRISRVEFTFPD----FVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKP 390
KRI ++ FPD V++ A+DLI +L +PS+R + +VL + WI + P
Sbjct: 8 KRIRSGQYDFPDPEWTNVSQAAKDLIKGMLNVDPSKRLCIEDVLRNKWIAQYDAVP 175
>20160
Length = 1277
Score = 38.5 bits (88), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 15/33 (45%), Positives = 24/33 (72%)
Frame = +2
Query: 354 EGARDLISRLLKHNPSQRPMLREVLEHPWITAN 386
E A DLI+R + +PS RP+L ++L+H W+T +
Sbjct: 332 EDAADLINRCIALDPSTRPVLADILKHKWMTKD 430
>00638
Length = 1595
Score = 38.1 bits (87), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 15/37 (40%), Positives = 21/37 (56%)
Frame = +2
Query: 223 QKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKP 259
Q F + Y+ EL AL +CHS ++HRD+KP
Sbjct: 392 QLYQTFTDYDIRFYLYELMKALDFCHSMGIMHRDVKP 502
>31789
Length = 676
Score = 36.6 bits (83), Expect = 0.018, Method: Compositional matrix adjust.
Identities = 27/103 (26%), Positives = 45/103 (43%), Gaps = 5/103 (4%)
Frame = +2
Query: 132 DFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHP 191
D EIGR G F VY + + +A L + K + + E E+ L+HP
Sbjct: 335 DVEIGR----GSFKTVYKGLDTELGVAVAWCELQDKKWNKT-ERQRFKEEAEMLKELQHP 499
Query: 192 NILRLYGYFHDATR-----VYLILEYAPLGTVYRELQKLSKFD 229
NI+R + Y+ + + L+ E GT+ L++ K +
Sbjct: 500 NIVRFFDYWEEHNHRNRKVIILVTELMTSGTLKTYLKRFKKIN 628
>36002
Length = 253
Score = 36.2 bits (82), Expect = 0.023, Method: Compositional matrix adjust.
Identities = 21/66 (31%), Positives = 31/66 (46%), Gaps = 5/66 (7%)
Frame = +1
Query: 324 VGKPPFEANTYQET-YKRISRVEFTFPDF----VTEGARDLISRLLKHNPSQRPMLREVL 378
V +P QE + RI + FP ++ A+DLI LL P +R +VL
Sbjct: 16 VAEPGEACQDCQELLFNRIQDGNYFFPSMEWSAISSSAKDLIRHLLVREPRKRYSAADVL 195
Query: 379 EHPWIT 384
+HPW+
Sbjct: 196 KHPWVC 213
>37063
Length = 455
Score = 35.4 bits (80), Expect = 0.043, Method: Compositional matrix adjust.
Identities = 23/77 (29%), Positives = 41/77 (53%), Gaps = 15/77 (19%)
Frame = -2
Query: 257 IKPENLLLGSAGE---LKIADF----GWSVHAPSSRRTTL---CGTLDYLPPEMIEGRM- 305
+KPEN+L E LKI DF G + ++ L G+ +Y+ PE+++ +
Sbjct: 454 LKPENILCEHLDEVVPLKICDFDLASGINCDGDGTKTPELLTPVGSAEYMAPEVVDAWVG 275
Query: 306 ----HDEKVDLWSLGVL 318
+D++ D+WSLG++
Sbjct: 274 ESFSYDKRCDMWSLGII 224
>20655
Length = 1181
Score = 34.7 bits (78), Expect = 0.068, Method: Compositional matrix adjust.
Identities = 17/56 (30%), Positives = 31/56 (55%), Gaps = 4/56 (7%)
Frame = +2
Query: 339 KRISRVEFTFP----DFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKP 390
KRI ++ FP V++ A+DLI +L +P +R +++V+ W+ N+ P
Sbjct: 8 KRIRNGQYEFPKPEWSRVSQDAKDLIRGMLCTDPDKRLNIKQVMASKWVADNTMVP 175
>00394
Length = 548
Score = 34.7 bits (78), Expect = 0.079, Method: Compositional matrix adjust.
Identities = 23/94 (24%), Positives = 43/94 (45%), Gaps = 5/94 (5%)
Frame = -2
Query: 137 RPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRL 196
+ +G+G F VY + + +A L + KA + + E E+ L+HPNI+R
Sbjct: 280 KEIGRGSFKTVYKGLDTELGVAVAWCELQDKKWNKAE-RQRFKEEAEMLKELQHPNIVRF 104
Query: 197 YGYFHDATR-----VYLILEYAPLGTVYRELQKL 225
+ Y+ + + L+ E GT+ L++
Sbjct: 103 FDYWEEHNHRNRKVIILVTELMTSGTLKTYLKRF 2
>18401
Length = 463
Score = 32.7 bits (73), Expect = 0.26, Method: Compositional matrix adjust.
Identities = 16/63 (25%), Positives = 29/63 (46%)
Frame = -3
Query: 287 TTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEF 346
+T+ T Y PE+I D+WS+G + +E G F+ + +E + R+
Sbjct: 458 STIVSTRHYRAPEVILELGWSHPCDVWSVGCIMFELYTGYTLFQTHDNKEHLAMMERILG 279
Query: 347 TFP 349
+ P
Sbjct: 278 SLP 270
>20773
Length = 391
Score = 32.0 bits (71), Expect = 0.48, Method: Compositional matrix adjust.
Identities = 17/54 (31%), Positives = 28/54 (51%)
Frame = -1
Query: 330 EANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWI 383
+ + ++R SR F VT+ +L+ RLL ++PSQR L HP++
Sbjct: 388 SGSCWSGLHRRRSRPVFPHTTVVTQHFYNLVQRLLTYDPSQRLTPDLALSHPFV 227
>21800
Length = 855
Score = 32.0 bits (71), Expect = 0.49, Method: Compositional matrix adjust.
Identities = 17/46 (36%), Positives = 26/46 (56%), Gaps = 5/46 (10%)
Frame = +2
Query: 237 ITELANALSYCHSK-RVIHRDIKPENLLLGSAG----ELKIADFGW 277
I ++ L+Y H+K +IH DIKPEN+L+ +L + F W
Sbjct: 650 IRQVLEGLNYLHAKCNIIHTDIKPENILICVDDNYIRKLAVDAFEW 787
>36481
Length = 806
Score = 32.0 bits (71), Expect = 0.51, Method: Compositional matrix adjust.
Identities = 32/141 (22%), Positives = 65/141 (46%), Gaps = 8/141 (5%)
Frame = +2
Query: 132 DFEIGRPLGKGKFGNVYLAREKQSKFILALKVL--FKAQLEKAGVE-HQLRREVEIQSHL 188
D ++ G+G FG V ++ +ALK++ E A +E + L + E H
Sbjct: 365 DMKLCPHWGEGTFGKVVQCKDLLKGDDIALKIIKNVDKYREAAKLEINVLEKLREKDPHA 544
Query: 189 RHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKF-----DEQRTATYITELANA 243
+H + L + + ++ + + LG + K + + ++ R +Y +L A
Sbjct: 545 KHMCVQMLDWFDYHG---HVCISFHMLGLSVFDFLKDNSYGAYPIEQVRHISY--QLCYA 709
Query: 244 LSYCHSKRVIHRDIKPENLLL 264
+++ H ++ H D+KPEN+L
Sbjct: 710 VNFLHENQLTHTDLKPENILF 772
>19872
Length = 446
Score = 31.6 bits (70), Expect = 0.53, Method: Compositional matrix adjust.
Identities = 14/41 (34%), Positives = 25/41 (60%), Gaps = 4/41 (9%)
Frame = +3
Query: 349 PDFVTEGA----RDLISRLLKHNPSQRPMLREVLEHPWITA 385
PDF + L+ ++L H+P+QRP R++L+ P++ A
Sbjct: 99 PDFTKDADLHNQSALLRQMLSHDPTQRPSSRDLLQSPYLPA 221
>17932
Length = 597
Score = 28.1 bits (61), Expect(2) = 0.76, Method: Compositional matrix adjust.
Identities = 14/31 (45%), Positives = 16/31 (51%), Gaps = 2/31 (6%)
Frame = -2
Query: 313 WSLGVLCYEFLVGKPPF--EANTYQETYKRI 341
WSLGV YE L G PF + + TY I
Sbjct: 593 WSLGVCAYEMLFGCTPFTDDDGSMVATYNNI 501
Score = 21.6 bits (44), Expect(2) = 0.76, Method: Compositional matrix adjust.
Identities = 14/32 (43%), Positives = 20/32 (62%)
Frame = -3
Query: 352 VTEGARDLISRLLKHNPSQRPMLREVLEHPWI 383
V++ ARDLIS+LL S R E+ +HP+
Sbjct: 460 VSKEARDLISQLLSDGKS-RLGWPELQQHPFF 368
>16350
Length = 1108
Score = 29.6 bits (65), Expect = 2.1, Method: Compositional matrix adjust.
Identities = 12/39 (30%), Positives = 23/39 (58%), Gaps = 1/39 (2%)
Frame = +3
Query: 358 DLISRLLKHNPSQRPMLREVLEHPWITANS-SKPSNCQN 395
D ++ +L+ +P QR + L+HPW+ ++ +PS Q
Sbjct: 762 DFLAPMLEFDPEQRATAAQSLQHPWLKLDA*PEPSGSQQ 878
>20513
Length = 405
Score = 29.3 bits (64), Expect = 2.9, Method: Compositional matrix adjust.
Identities = 12/39 (30%), Positives = 23/39 (58%), Gaps = 1/39 (2%)
Frame = -1
Query: 358 DLISRLLKHNPSQRPMLREVLEHPWITANS-SKPSNCQN 395
D ++ +L+ +P QR + L+HPW+ ++ +PS Q
Sbjct: 282 DFLAPMLEFDPEQRATAAQSLQHPWLKLDA*PEPSGSQQ 166
>17644
Length = 463
Score = 27.7 bits (60), Expect = 8.1, Method: Compositional matrix adjust.
Identities = 13/32 (40%), Positives = 19/32 (59%)
Frame = +3
Query: 352 VTEGARDLISRLLKHNPSQRPMLREVLEHPWI 383
VT+ BL+ RLL ++PSQR L HP++
Sbjct: 69 VTQHFYBLVQRLLTYDPSQRLTPDLALSHPFV 164
>18929
Length = 440
Score = 27.7 bits (60), Expect = 9.8, Method: Compositional matrix adjust.
Identities = 11/38 (28%), Positives = 22/38 (57%)
Frame = +1
Query: 348 FPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITA 385
F + ++ + +I R++ +P QRP ++L HP + A
Sbjct: 34 FINTISVELQQVIRRMMSPDPRQRPTANQLLAHPTLAA 147
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000360407 | hsapiens_gene_ensembl |
Serine/threonine-protein kinase 6 (EC 2.7.11.1) (Aurora kinase A)
(Aurora-A) (Serine/threonine kinase 15) (Aurora/IPL1-related kinase 1)
(Aurora-related kinase 1) (hARK1) (Breast-tumor-amplified kinase).
[Source:Uniprot/SWISSPROT;Acc:O14965]
(403 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
21433 184 3e-69
15910 120 8e-28
03240 119 2e-27
01060 117 6e-27
00300 114 8e-26
30755 110 1e-24
18484 110 1e-24
18921 107 7e-24
12721 105 4e-23
14420 101 5e-22
01707 99 3e-21
14126 98 5e-21
09606 97 8e-21
06405 97 9e-21
09007 94 8e-20
13592 93 2e-19
13212 92 3e-19
01392 91 1e-18
01756 87 1e-17
13066 87 1e-17
11780 80 2e-17
04591 86 2e-17
01718 86 3e-17
17975 85 4e-17
31885 84 7e-17
27546 83 2e-16
00486 82 3e-16
21079 82 6e-16
00392 80 1e-15
01966 79 3e-15
19761 76 2e-14
19094 70 6e-14
26560 75 7e-14
29581 72 4e-13
20152 69 3e-12
27405 68 7e-12
26711 66 3e-11
19301 65 5e-11
38560 65 6e-11
14477 64 1e-10
04852 64 1e-10
06358 64 1e-10
04138 64 2e-10
21808 63 2e-10
00715 62 5e-10
14116 61 6e-10
28157 61 8e-10
12672 61 9e-10
07940 61 1e-09
03508 61 1e-09
26009 41 3e-09
12786 59 3e-09
18663 58 7e-09
28638 56 3e-08
02638 53 2e-07
11185 52 3e-07
25019 52 4e-07
29590 39 1e-06
27274 50 2e-06
31120 49 4e-06
37602 49 4e-06
07833 48 6e-06
32000 48 6e-06
07291 48 8e-06
01106 47 2e-05
18481 45 6e-05
32957 45 6e-05
31489 44 1e-04
16708 44 1e-04
17253 44 1e-04
20640 44 1e-04
07836 43 3e-04
20559 40 3e-04
17300 42 4e-04
11404 41 0.001
21210 40 0.001
21418 40 0.002
20160 39 0.006
00638 38 0.006
31789 37 0.018
36002 36 0.023
37063 35 0.043
20655 35 0.068
00394 35 0.079
18401 33 0.26
20773 32 0.48
21800 32 0.49
36481 32 0.51
19872 32 0.53
17932 28 0.76
16350 30 2.1
20513 29 2.9
17644 28 8.1
18929 28 9.8
>21433
Length = 590
Score = 184 bits (467), Expect(2) = 3e-69, Method: Compositional matrix adjust.
Identities = 93/136 (68%), Positives = 107/136 (78%)
Frame = +2
Query: 231 QRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLC 290
+RTA YI +L++AL YCH ++VIHRDIKPENLLLG G+LKIADFGWSVHAPSSRRTT+C
Sbjct: 167 KRTACYIYQLSSALEYCHYRKVIHRDIKPENLLLGLKGDLKIADFGWSVHAPSSRRTTMC 346
Query: 291 GTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPD 350
GTLDYLPPEM+EG+ HDE VDLWSLGVLCYEFLVG PP + + R P
Sbjct: 347 GTLDYLPPEMVEGKTHDENVDLWSLGVLCYEFLVGTPPLRPSPTRPPTPASPRWTSGSPS 526
Query: 351 FVTEGARDLISRLLKH 366
VT GARDLIS+LL+H
Sbjct: 527 IVTPGARDLISKLLRH 574
Score = 95.9 bits (237), Expect(2) = 3e-69, Method: Compositional matrix adjust.
Identities = 44/64 (68%), Positives = 54/64 (84%), Gaps = 1/64 (1%)
Frame = +3
Query: 176 HQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDE-QRTA 234
HQLRRE+EIQSHLRH NILR++GYFHD TRVYLILE+AP G +Y+ELQ+ KFDE ++ A
Sbjct: 3 HQLRREIEIQSHLRHDNILRMFGYFHDKTRVYLILEFAPKGELYKELQRCHKFDENEQHA 182
Query: 235 TYIT 238
Y +
Sbjct: 183 IYTS 194
>15910
Length = 1361
Score = 120 bits (302), Expect = 8e-28, Method: Compositional matrix adjust.
Identities = 61/177 (34%), Positives = 104/177 (58%), Gaps = 8/177 (4%)
Frame = +2
Query: 226 SKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLL---LGSAGELKIADFGWS-VHA 281
++ E+ A I+++ + + Y H+ V+HRD+KPENLL + +LK+ADFG S +
Sbjct: 449 GQYTEKDAARAISDILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLADFGLSRIIE 628
Query: 282 PSSRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRI 341
P + +T+CGT Y PE+++G + VD+WS+GV+ Y L G PF A E Y++I
Sbjct: 629 PEVQMSTVCGTPGYCAPEVLKGDKYTPSVDMWSVGVIAYILLCGYEPFFAENEFEMYRKI 808
Query: 342 SRVEFTFPD----FVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQ 394
+ E+ F + ++E A+D++ +LL +P +R E L PW+ ++K +N +
Sbjct: 809 IKGEYKFDEEYWSEISENAKDVVRKLLVIDPKKRLTATEALRLPWVKGVATKTTNME 979
>03240
Length = 1683
Score = 119 bits (298), Expect = 2e-27, Method: Compositional matrix adjust.
Identities = 86/283 (30%), Positives = 133/283 (46%), Gaps = 52/283 (18%)
Frame = -3
Query: 133 FEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPN 192
FE + LG G FG V L R+ + + A+K L K+ + K ++ E +I + +
Sbjct: 1285 FEKIKTLGVGAFGEVSLCRKNDTGMLYAMKTLRKSDVLKRNQVAHVKAERDILAEADNEW 1106
Query: 193 ILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRV 252
+++LY F D +Y +++Y P G + L ++ DE Y+ EL A+ H
Sbjct: 1105 VVKLYYSFQDHNYLYFVMDYVPGGDLMGLLIRMEILDEPLARFYVAELVQAIESVHRMGF 926
Query: 253 IHRDIKPENLLLGSAGELKIADFG------WS----------VHA--------------- 281
IHRDIKP+N+L+ G +K+ DFG W+ HA
Sbjct: 925 IHRDIKPDNILIDRNGHIKLTDFGLCTGFRWTHNSKYYQRDGTHARQDSMEVKCQLDEQC 746
Query: 282 ------PSSRRT---------TLCGTLDYLPPEMIEGRM--HDEKVDLWSLGVLCYEFLV 324
P RR +L GT +Y+ PE++ R+ + D WS+GV+ +E LV
Sbjct: 745 QCEILKPLERRRKREQRCLAHSLVGTPNYIAPEVL-SRLGGYTSVCDWWSVGVILFEMLV 569
Query: 325 GKPPFEANTYQET-YKRIS---RVEFTFPDFVTEGARDLISRL 363
G PPF ANT ET YK I+ ++ +++ A+DLI RL
Sbjct: 568 GHPPFYANTPAETQYKVINWKDMLKIPRESNLSQPAKDLILRL 440
>01060
Length = 1800
Score = 117 bits (294), Expect = 6e-27, Method: Compositional matrix adjust.
Identities = 83/305 (27%), Positives = 145/305 (47%), Gaps = 36/305 (11%)
Frame = +1
Query: 129 ALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHL 188
AL D + +G+G +G VY R + + LA+K + + + + GV RE+ + L
Sbjct: 67 ALSDLTDFQKIGEGTYGVVYKCRHRATGRKLAMKKI-RLRGSEDGVPSSAIREIAMLREL 243
Query: 189 RHPNILRLYGYFHDATRVYLILEY--APLGTVYRELQKLSKFDEQRTATYITELANALSY 246
RH NI+ L + R++L+ E+ L + + D + +Y+ ++ + +
Sbjct: 244 RHTNIVCLEDVIMEDERLFLVFEFLSMDLKMYIDKFPEGVVLDRRLVKSYVFQIVTGIXF 423
Query: 247 CHSKRVIHRDIKPENLLLGSAGELKIADFGW--SVHAPSSRRTTLCGTLDYLPPEMIEG- 303
CH +R++HRD+KP+NLL+ G +KIADFG + P T TL Y PE++ G
Sbjct: 424 CHQRRIVHRDLKPQNLLINHTGAIKIADFGMARTFALPVRAYTHEVVTLWYRAPEILMGA 603
Query: 304 RMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRV-----EFTFPDF------- 351
+ VD+WS+G + + L+ P F+ ++ + +I R+ E T+P+F
Sbjct: 604 SKYSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKLPAFN 783
Query: 352 -----------------VTEGARDLISRLLKHNPSQRPMLREVLEHPWI--TANSSKPSN 392
+ DLI R LK +P+QR +++L+H + S KP +
Sbjct: 784 GMFPLWKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYFLNVDTSVKPVD 963
Query: 393 CQNKE 397
+ E
Sbjct: 964 VPSPE 978
>00300
Length = 2318
Score = 114 bits (285), Expect = 8e-26, Method: Compositional matrix adjust.
Identities = 74/257 (28%), Positives = 125/257 (48%), Gaps = 10/257 (3%)
Frame = -1
Query: 136 GRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILR 195
G +G+G+FG VY A + ++ALK + K Q ++ E++I ++H N+++
Sbjct: 1643 GNKIGEGQFGKVYTAVNMSTGELMALKEM-KFQPNDLQQLREMCDEIKIFEGIQHENLVK 1467
Query: 196 LYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHR 255
YG + + +EY GT+ E K+ E Y E+ A+++ H ++HR
Sbjct: 1466 YYGVEVHKDEMLMFMEYCDTGTI-EEAAKMG-LPEYLIRRYTREIVLAVNHLHENSIVHR 1293
Query: 256 DIKPENLLLGSAGELKIADFGWSVHAPSSRRT-----TLCGTLDYLPPEMI---EGRMHD 307
DIK N+ L S G +K+ DFG SV S L GT Y+ PE+ + +
Sbjct: 1292 DIKGANIFLTSNGHVKLGDFGCSVKLKSHTTMPGEFHNLVGTTAYMAPEVFTQNDQGGYG 1113
Query: 308 EKVDLWSLGVLCYEFLVGKPPFE--ANTYQETYKRISRVEFTFPDFVTEGARDLISRLLK 365
D+WSLG + E GK P+ N YQ YK + PD ++ + + ++
Sbjct: 1112 RAADIWSLGCVVIEMATGKRPWHDLDNNYQIMYKVGIGHKPAVPDSLSVEGKHFLDLIMC 933
Query: 366 HNPSQRPMLREVLEHPW 382
H+P+QR + ++L+H +
Sbjct: 932 HDPAQRALASQLLDHTF 882
>30755
Length = 1137
Score = 110 bits (275), Expect = 1e-24, Method: Compositional matrix adjust.
Identities = 60/165 (36%), Positives = 91/165 (55%), Gaps = 7/165 (4%)
Frame = +2
Query: 228 FDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRT 287
F E+RT Y E+ +AL Y HS+ +I+RD+K ENLLL G +K+ADFG + RT
Sbjct: 23 FTEERTRFYGAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCKEDITYGRT 202
Query: 288 T--LCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVE 345
T CGT +YL PE+++ + VD W GV+ YE + G+ PF + + I +
Sbjct: 203 TKTFCGTPEYLAPEVLDDNDYGRAVDWWGTGVVMYEMICGRLPFYNRDHDVLFTLILVED 382
Query: 346 FTFPDFVTEGARDLISRLLKHNPSQR-----PMLREVLEHPWITA 385
FP +T+ A+ L+S LL +P R ++E+ HP+ +
Sbjct: 383 VKFPRNITDEAKSLLSGLLAKDPRNRLGGGQDDVKEIQAHPFFAS 517
>18484
Length = 635
Score = 110 bits (275), Expect = 1e-24, Method: Compositional matrix adjust.
Identities = 57/156 (36%), Positives = 89/156 (57%), Gaps = 2/156 (1%)
Frame = +1
Query: 218 VYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGW 277
+YR +Q+ KF E A Y E+A L + H + +I+RD+K +N++L S G +KIADFG
Sbjct: 7 MYR-IQQEGKFKEPVAAFYAAEIAVGLFFLHDQGIIYRDLKLDNVMLDSEGHIKIADFGM 183
Query: 278 SVHAPSSRRTT--LCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQ 335
+ TT CGT DY+ PE++ + + + VD W+ GVL +E L G+PPF+
Sbjct: 184 CKEGMTGDATTRTFCGTPDYIAPEIVLYQPYSKSVDWWAYGVLLFEMLAGQPPFDGEDED 363
Query: 336 ETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQR 371
E + I+ ++P ++ A L LL NP++R
Sbjct: 364 ELFSSITDHNVSYPKAMSREAVSLCKGLLMKNPTKR 471
>18921
Length = 697
Score = 107 bits (268), Expect = 7e-24, Method: Compositional matrix adjust.
Identities = 64/199 (32%), Positives = 109/199 (54%), Gaps = 3/199 (1%)
Frame = +2
Query: 133 FEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPN 192
F+I LG+G +G+V+ + K++ +LA+K Q+ ++ +E+ I
Sbjct: 35 FDILGKLGEGSYGSVFKSLHKETGQVLAIK-----QVPVDTDLQEIIKEISIMQQCDSKY 199
Query: 193 ILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSK-FDEQRTATYITELANALSYCHSKR 251
I++ YG + T +++++EY G+V ++ +K E+ AT + L Y HS+R
Sbjct: 200 IVKYYGSYFKNTDLWIVMEYCGAGSVSDIMRLRNKTLVEREIATILYYTLKGLXYLHSRR 379
Query: 252 VIHRDIKPENLLLGSAGELKIADFGWS--VHAPSSRRTTLCGTLDYLPPEMIEGRMHDEK 309
IHRDIK N+LL + G K+ADFG + + ++R T+ GT ++ PE+I+ +D
Sbjct: 380 KIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTPYWMAPEVIQEIGYDCV 559
Query: 310 VDLWSLGVLCYEFLVGKPP 328
D+WSLG+ E GKPP
Sbjct: 560 ADIWSLGITALEMAEGKPP 616
>12721
Length = 821
Score = 105 bits (261), Expect = 4e-23, Method: Compositional matrix adjust.
Identities = 69/247 (27%), Positives = 123/247 (49%), Gaps = 5/247 (2%)
Frame = +1
Query: 130 LEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLR 189
L+DF +G+G G V +A + + +A+K K L K L EV +
Sbjct: 94 LDDF---MKIGEGSTGIVCIATSRDGR-QMAVK---KMDLRKQQRRELLFNEVVVMRDYH 252
Query: 190 HPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHS 249
HPNI+ +Y + +++++E+ G ++ ++ DE + AT AL++ H+
Sbjct: 253 HPNIVEMYNSYLVNDELWVVMEFME-GGALTDIVTNNRMDEVQIATVCRACLKALAFLHA 429
Query: 250 KRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSS--RRTTLCGTLDYLPPEMIEGRMHD 307
VIHRDIK +++LL G++K+ DFG+ +R +L GT ++ PE+I +
Sbjct: 430 NGVIHRDIKSDSILLSHDGKVKLXDFGFCAQVTQDLQKRKSLVGTPYWMAPEVISRLPYG 609
Query: 308 EKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRV---EFTFPDFVTEGARDLISRLL 364
+VD+WSLG++ E + +PPF + +RI + + ++ + I R+L
Sbjct: 610 PEVDIWSLGIMVMEMIDAEPPFFNEPPLQAMRRIRDMPPPKLRNTHKISPRLQGFIDRML 789
Query: 365 KHNPSQR 371
+P QR
Sbjct: 790 VRDPHQR 810
>14420
Length = 528
Score = 101 bits (252), Expect = 5e-22, Method: Compositional matrix adjust.
Identities = 48/151 (31%), Positives = 87/151 (57%), Gaps = 2/151 (1%)
Frame = +2
Query: 181 EVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITEL 240
E+ + ++PNI+ + +++++E+ G++ + + + DE + A E
Sbjct: 50 EILVMRENQNPNIVNYLDSYLVGEELWVVMEFLAGGSLTDVVTE-TCMDEGQIAAVCREC 226
Query: 241 ANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAP--SSRRTTLCGTLDYLPP 298
AL + H +VIHRDIK +N+LLG G +K+ DFG+ S+R+T+ GT ++ P
Sbjct: 227 LQALEFLHENQVIHRDIKSDNILLGMDGSVKLTDFGFCAQLSPEQSKRSTMVGTPYWMAP 406
Query: 299 EMIEGRMHDEKVDLWSLGVLCYEFLVGKPPF 329
E++ + + VD+WSLGV+C E + G+PP+
Sbjct: 407 EVVTRKQYGPTVDIWSLGVMCIEMIEGEPPY 499
>01707
Length = 757
Score = 99.0 bits (245), Expect = 3e-21, Method: Compositional matrix adjust.
Identities = 58/201 (28%), Positives = 108/201 (53%), Gaps = 4/201 (1%)
Frame = +1
Query: 130 LEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLR 189
+E +E +G+G +G V+ R K++ ++A+K +++ + ++ RE+ + L+
Sbjct: 61 MEKYEKIGKIGEGSYGVVFKCRNKETSQLVAIKKFVESE-DDPLIKKIAMREIRMLKQLK 237
Query: 190 HPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSK-FDEQRTATYITELANALSYCH 248
HPN++RL F R++L+ +Y T+ EL + + E I + A+++CH
Sbjct: 238 HPNLVRLIEVFRRKKRLHLVFDYVD-HTLLNELDRYPRGLPEPMVKRIIYQTLLAVNFCH 414
Query: 249 SKRVIHRDIKPENLLLGSAGELKIADFGWS--VHAPSSRRTTLCGTLDYLPPEMIEGRM- 305
IHRD+KPEN+L+ G++K+ DFG++ + P T T Y PE++ G
Sbjct: 415 QYNTIHRDVKPENILITRQGQVKLCDFGFARILTGPGDEYTDYVATRWYRAPELLVGDTQ 594
Query: 306 HDEKVDLWSLGVLCYEFLVGK 326
+ VD+W++G + E L G+
Sbjct: 595 YGPPVDVWAIGCVFAELLTGQ 657
>14126
Length = 1265
Score = 98.2 bits (243), Expect = 5e-21, Method: Compositional matrix adjust.
Identities = 86/332 (25%), Positives = 146/332 (43%), Gaps = 46/332 (13%)
Frame = +3
Query: 116 SKQKNEESKKRQWALEDFEIGRPLGKGKFGNVYLARE--KQSKFILALKVLFKAQLEKAG 173
S+ + S++R + +E +G G +G VY AR+ Q +F+ ++ E G
Sbjct: 144 SESAAKMSRRRDSTEQKYEEVAVIGNGAYGTVYKARDLRNQGEFVAMKRIRLNNTEE--G 317
Query: 174 VEHQLRREVEIQSHLR---HPNILRLYGYFHDAT-----RVYLILEYA--PLGTVYRELQ 223
+ RE+ + L HPN++RL H+ R+ L+ EY L T Y
Sbjct: 318 MPMMAIREISMLKQLEQYEHPNVVRLLDVSHNTITDREIRLNLVFEYIEHDLAT-YLAKC 494
Query: 224 KLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS-VHAP 282
R + +L N + + HS R++HRD+KP+NLL+ G LK+ADFG + +++
Sbjct: 495 PSPGLGPDRIKDLMLQLLNGVDFLHSNRIVHRDLKPQNLLISKDGRLKLADFGLARIYSF 674
Query: 283 SSRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRIS 342
TT+ TL Y PE++ + VD+WS G + E + F+ ++ + K+I
Sbjct: 675 HMALTTVVVTLWYRSPEVLMQAEYGTSVDIWSCGCIFAELFTRRALFKGSSEFDQLKKIF 854
Query: 343 RV-----EFTFPDFVTEG----------------------ARDLISRLLKHNPSQRPMLR 375
V +P+ V+ A+DL+ ++L +R R
Sbjct: 855 EVIGLPPAGDWPEGVSVHRNSFRPTPPVPLQTLVPEMDPQAKDLMEKMLVFKSGRRISSR 1034
Query: 376 EVLEHPWITAN------SSKPSNCQNKESASK 401
E L HP++ + SS S +N S +
Sbjct: 1035ESLLHPYLRDDLDSIRTSSSLSTSENDSSDGR 1130
>09606
Length = 1300
Score = 97.4 bits (241), Expect = 8e-21, Method: Compositional matrix adjust.
Identities = 66/285 (23%), Positives = 126/285 (44%), Gaps = 34/285 (11%)
Frame = -3
Query: 130 LEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLR 189
+E+F + LGKG+ +Y R K + +A+ + K + ++ V + +
Sbjct: 1118 MENFVLYEELGKGEHSIIYKGRRKGTINFVAIHCIEKCK------RPEVTNTVRMTHDIS 957
Query: 190 HPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHS 249
HPN+++ + ++ + ++L++E G++ L + E + L L Y HS
Sbjct: 956 HPNVVQFHEWYETSNHLWLVVELCTGGSLADILAQDHHLPETSIRDFGIHLVTGLHYIHS 777
Query: 250 KRVIHRDIKPENLLLGSAGELKIADFG----------------------WSVHAPSS--R 285
++ D++P +LL ++G LK ADFG W++ + +
Sbjct: 776 LGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQWNIQSAEEMMK 597
Query: 286 RTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVE 345
+ G+ Y+ PE+ +G DLW+LG + YE G PPF TY T ++ E
Sbjct: 596 QVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSGHPPFLGETYDITKDKVLNKE 417
Query: 346 FTFPDFVTEGAR----------DLISRLLKHNPSQRPMLREVLEH 380
F P +G+R +L+ LL+ + ++R +++H
Sbjct: 416 FPLPK--VKGSRLSAKPSPEFLNLLESLLQKDSTRRLSWASLVKH 288
>06405
Length = 1965
Score = 97.4 bits (241), Expect = 9e-21, Method: Compositional matrix adjust.
Identities = 68/260 (26%), Positives = 118/260 (45%), Gaps = 9/260 (3%)
Frame = +1
Query: 127 QWALEDFEIGRP--LGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEI 184
+W +E EI LG G++G+VY A K+ I+A+K L E + E I
Sbjct: 241 RWEIERTEIAMKHRLGGGQYGDVYEAMWKRYNKIVAVKTL----KEDTMALNDFLEEAAI 408
Query: 185 QSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTA-TYI-TELAN 242
++HPN+++L G Y++ E+ P G + L+ ++ + TA Y+ T++A+
Sbjct: 409 MKEMKHPNLVQLLGVCTREPPFYIVTEFMPHGNLLDYLRSSTREENGPTALMYMATQIAS 588
Query: 243 ALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGT---LDYLPPE 299
++Y +K IHRD+ N L+ + +K+ADFG + T G + + PE
Sbjct: 589 GMAYLETKNFIHRDLAARNCLVADSNMVKVADFGLARLMKDDTYTAHIGAKFPIKWTAPE 768
Query: 300 MIEGRMHDEKVDLWSLGVLCYEFLV-GKPPFEANTYQETYKRISR-VEFTFPDFVTEGAR 357
+ + D+W+ GVL +E G P+ E Y + R P
Sbjct: 769 GLAFNRFSTRSDIWAFGVLLWELATYGMSPYPGVELTEVYHLLERGYRMERPPGTPADVY 948
Query: 358 DLISRLLKHNPSQRPMLREV 377
L+ + + +P RP +E+
Sbjct: 949 ILMLKCWQWDPKDRPTFKEI 1008
>09007
Length = 1440
Score = 94.4 bits (233), Expect = 8e-20, Method: Compositional matrix adjust.
Identities = 71/264 (26%), Positives = 122/264 (46%), Gaps = 20/264 (7%)
Frame = -1
Query: 135 IGRPLGKGKFGNVYLA---REKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHP 191
+ + LG+G FG V A E K +A+K L K ++ K G E +E I L H
Sbjct: 867 LSKSLGQGHFGTVRQAIWTAESGEKVQVAVKCLSKDKIHKDGQE--FLKETAIMQMLDHE 694
Query: 192 NILRLYGYFHD-ATRVYLILEYAPLGTVYRELQKLS---KFDEQRTATYITELANALSYC 247
NI+R+YG D + L+ E AP+ ++ ++++S F R + ++ + +SY
Sbjct: 693 NIVRVYGVVMDNGADIMLVTELAPMRSLLECVKEVSARVDFSVPRLCDFSQQVCDGMSYL 514
Query: 248 HSKRVIHRDIKPENLLLGSAGELKIADFGWSV-------HAPSSRRTTLCGTLDYLPPEM 300
SKR++HRD+ N+LL S ++KI+D G S + S + L + + PE
Sbjct: 513 ESKRLVHRDLAARNILLFSKSKVKISDVGVSGALGAGKEYYQSQQTIHLQNAVAWCAPES 334
Query: 301 IEGRMHDEKVDLWSLGVLCYEFLV-GKPPFEANTYQETYKRIS-----RVEFTFPDFVTE 354
D+W+ GVL +EF G P+ Q+ + + R+E PD +
Sbjct: 333 FRNLCFSSASDVWAFGVLLWEFFTHGFQPWAGLNGQQIMEAVDAPQSQRLE--QPDLCPK 160
Query: 355 GARDLISRLLKHNPSQRPMLREVL 378
++ + + P +RP ++
Sbjct: 159 EYYAVMLKCWEQEPQRRPTFSQLF 88
>13592
Length = 980
Score = 93.2 bits (230), Expect = 2e-19, Method: Compositional matrix adjust.
Identities = 68/270 (25%), Positives = 128/270 (47%), Gaps = 14/270 (5%)
Frame = +2
Query: 139 LGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYG 198
+G+G+FG VY A + ++A+K + E +++ + E++I ++H N++R YG
Sbjct: 8 IGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETRALKN-VAEELKILEGIKHKNLVRYYG 184
Query: 199 YFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIK 258
+ + +E GT+ ++ E + + +L + ++ H ++HRDIK
Sbjct: 185 IEVHREELLIFMELCSEGTLESLVELTGGLPEALSRRFTAQLLSGVAELHKHGIVHRDIK 364
Query: 259 PENL-LLGSAGELKIADFGWSVHAPSSRRTTL-------CGTLDYLPPEMI---EGRMHD 307
N+ L+ + LK+ DFG +V + TT+ GT Y+ PE+ H
Sbjct: 365 TANIFLVDGSNSLKLGDFGSAVKIQA--HTTVPGELQGYVGTQAYMAPEVFTKTNSDGHG 538
Query: 308 EKVDLWSLGVLCYEFLVGKPP---FEANTYQETYKRISRVEFTFPDFVTEGARDLISRLL 364
D+WS+G + E GK P F++N +Q +K + P+ +++ D I L
Sbjct: 539 RLADIWSVGCVVVEMASGKRPWAQFDSN-FQIMFKVGMGEKPQAPESLSQEGHDFIDHCL 715
Query: 365 KHNPSQRPMLREVLEHPWITANSSKPSNCQ 394
+H+P QR E+LE + + + N +
Sbjct: 716 QHDPKQRLSAIELLEQNFCKSGRDEECNSE 805
>13212
Length = 1067
Score = 92.4 bits (228), Expect = 3e-19, Method: Compositional matrix adjust.
Identities = 60/188 (31%), Positives = 96/188 (51%), Gaps = 10/188 (5%)
Frame = -1
Query: 206 VYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLG 265
V+ +L + L ++ +L+K E + E+ AL + H VIHRDIK N+LL
Sbjct: 1049 VFRVLWWGALDSIMVDLEK--PMTEAQICYVCHEMCMALDFLHRHHVIHRDIKAGNVLLT 876
Query: 266 SAGELKIADFGWSVHAPSS--RRTTLCGTLDYLPPEMI-----EGRMHDEKVDLWSLGVL 318
GE+K+ADFG S + +R T GT ++ PE++ + +D K D+WSLGV
Sbjct: 875 IDGEVKLADFGVSAKNTQTQQKRDTFIGTPYWMAPEVVLCETLKDTPYDFKADIWSLGVT 696
Query: 319 CYEFLVGKPPFEANTYQETYKRISRVE---FTFPDFVTEGARDLISRLLKHNPSQRPMLR 375
EF +PP + +I + + P T+ +D I++ L +P+ RP
Sbjct: 695 LIEFAQIEPPNKEMHPMRVLIKIHKSDPPTLEKPKKWTKLFKDFIAKCLVKDPNLRPTAA 516
Query: 376 EVLEHPWI 383
E+LEHP++
Sbjct: 515 ELLEHPFM 492
>01392
Length = 1806
Score = 90.5 bits (223), Expect = 1e-18, Method: Compositional matrix adjust.
Identities = 57/189 (30%), Positives = 90/189 (47%), Gaps = 34/189 (17%)
Frame = -1
Query: 230 EQRTATYITELANALSYCHSKRVIHRDIKPENLL---LGSAGELKIADF----GWSVHAP 282
E+ + + +A AL + HSK + HRD+KPEN+L L +KI DF G S
Sbjct: 1794 EREASLVVRHIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGISCDGD 1615
Query: 283 SSRRTTL---CGTLDYLPPEMIEGRM-----HDEKVDLWSLGVLCYEFLVGKPPFEANTY 334
++ L G+ +Y+ PE+++ + +D++ DLWSLG++ Y L G PPF
Sbjct: 1614 GTKTPELLTPVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILYIMLCGYPPFYGQCG 1435
Query: 335 QET---------------YKRISRVEFTFPD----FVTEGARDLISRLLKHNPSQRPMLR 375
++ + I + FP ++ A+DLI LL P +R
Sbjct: 1434 EDCGWNRGEACHDCQDMLFNSIQDGHYKFPSQEWTSISSSAKDLIRHLLVREPRKRYSAA 1255
Query: 376 EVLEHPWIT 384
+VL+HPWI
Sbjct: 1254 DVLKHPWIC 1228
>01756
Length = 1858
Score = 87.0 bits (214), Expect = 1e-17, Method: Compositional matrix adjust.
Identities = 66/222 (29%), Positives = 106/222 (47%), Gaps = 16/222 (7%)
Frame = -3
Query: 139 LGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYG 198
+G+G FG V+ AR K++K ++A+K + EK G RE++I L H N++ L
Sbjct: 1718 IGQGTFGEVFKARCKKTKQVVAMKKVLMDN-EKEGFPITALREIKILQLLNHENVVDLIE 1542
Query: 199 YFH----DATR----VYLILEYA--PLGTVYRELQKLSKFDEQRTATYITELANALSYCH 248
A R YL+ E+ L + + + E + + +L N L Y H
Sbjct: 1541 ICSTKATSANRYKSMFYLVFEFCEHDLAGLLSNMSVVFNLPEIKEV--MKQLMNGLYYIH 1368
Query: 249 SKRVIHRDIKPENLLLGSAGELKIADFG----WSVHAPS-SRRTTLCGTLDYLPPEMIEG 303
+++HRD+K N+L+ G LK+ADFG +SV+ +R T TL Y PPE++ G
Sbjct: 1367 RNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRPPELLLG 1188
Query: 304 -RMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRV 344
R + +D W G + E P + T Q I+++
Sbjct: 1187 DRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQNQLTLITQL 1062
>13066
Length = 551
Score = 87.0 bits (214), Expect = 1e-17, Method: Compositional matrix adjust.
Identities = 50/164 (30%), Positives = 87/164 (53%), Gaps = 6/164 (3%)
Frame = +3
Query: 159 LALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTV 218
LA K++ K + VE RE+++ + L HP I++++ + ++ + +A G +
Sbjct: 60 LACKIIDKEKAPVDFVEKFFPRELDLLTKLDHPYIIQIHSILQRXPKNFIFMRFAERGDL 239
Query: 219 YRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS 278
+Q++ E++ + ++ AL+Y HS V HRD+K EN+LL S +K+ADFG++
Sbjct: 240 LTYIQEVGFVKEKQAKIWFYQMTTALNYLHSYDVAHRDLKCENILLSSHFNVKLADFGFA 419
Query: 279 VHAPSS-----RRTTLCGTLDYLPPEMIEGRMHDEKV-DLWSLG 316
+ T CG+ Y PE++ G + KV D WSLG
Sbjct: 420 CACITESGEKYMSRTYCGSAAYAAPEIVYGAPYAPKVADAWSLG 551
>11780
Length = 1713
Score = 80.1 bits (196), Expect(2) = 2e-17, Method: Compositional matrix adjust.
Identities = 57/202 (28%), Positives = 100/202 (49%), Gaps = 7/202 (3%)
Frame = +3
Query: 121 EESKKRQW--ALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQL 178
+E K W A +D EIG +GKG FG+VY + V K +K E
Sbjct: 561 QEFKSGGWVIAXQDLEIGEAIGKGDFGDVYKGMYRGQP------VAIKQLKDKDRGEQSF 722
Query: 179 RREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSK--FDEQRTATY 236
+E + + LRH N++RL G T ++L+ E+ G + L+ + ++ +
Sbjct: 723 LQEASVMTSLRHDNLVRLIGVVLGET-IFLVTEFMGKGNLVEYLRSRGRSVITKKDQINF 899
Query: 237 ITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYL 296
T+ A+ Y SKR++HRD+ N+L+ G+ K++DFG + S +T++ + +
Sbjct: 900 ATDTCAAMEYLESKRLVHRDLAARNVLVHDDGKAKVSDFGLAKFGDFS-QTSVKFPIKWT 1076
Query: 297 PPEMI-EGRMHDE--KVDLWSL 315
PE + E ++H + V+LW +
Sbjct: 1077APEALRENKIH*QVRHVELWHI 1142
Score = 26.6 bits (57), Expect(2) = 2e-17, Method: Compositional matrix adjust.
Identities = 16/72 (22%), Positives = 33/72 (45%), Gaps = 2/72 (2%)
Frame = +1
Query: 309 KVDLWSLGVLCYE-FLVGKPPFEANTYQETYKRISR-VEFTFPDFVTEGARDLISRLLKH 366
K D+WS G+L +E + G+ P+ + + R P+ ++ + +
Sbjct: 1114 KSDMWSFGILLWEIYSFGRVPYPRIPLTDVVMHVERGYRMEAPEGCPPEIYSIMKQAWEL 1293
Query: 367 NPSQRPMLREVL 378
+P++RP + VL
Sbjct: 1294 DPNERPTFKSVL 1329
>04591
Length = 1117
Score = 86.3 bits (212), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 60/184 (32%), Positives = 88/184 (47%), Gaps = 12/184 (6%)
Frame = -2
Query: 171 KAGVEHQLRREVEIQSHLRHPNILRLYGYFHD--------ATRVYLILEYAP--LGTVYR 220
K G RE++I L H N+++L H + YLI EY L +
Sbjct: 1101 KEGFPITALREIKILQQLEHENVVQLQEICHTQAGPYNRYKSTFYLIFEYCDYDLAGLLN 922
Query: 221 ELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSV- 279
L+ KF +++L N L Y H+K+++HRDIK N+LL G LK+ADFG S
Sbjct: 921 NLR--VKFSLADKKNLMSQLLNGLFYIHTKQILHRDIKAANILLTRDGVLKLADFGLSRP 748
Query: 280 HAPSSRRTTLCGTLDYLPPEMIEG-RMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETY 338
S R T TL Y PPE++ G R + ++D+W +G + E KP + + Q
Sbjct: 747 WVKSKRLTNRVVTLWYRPPELLLGEREYGPEIDMWGVGCIMAEMWSRKPLMQGRSEQHQL 568
Query: 339 KRIS 342
I+
Sbjct: 567 SLIT 556
>01718
Length = 959
Score = 85.9 bits (211), Expect = 3e-17, Method: Compositional matrix adjust.
Identities = 62/209 (29%), Positives = 99/209 (47%), Gaps = 11/209 (5%)
Frame = +3
Query: 130 LEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLR 189
L+DF I +G G F V+ + + ++ALK+ H + REV++ + L+
Sbjct: 147 LDDF-ICEKIGAGFFSEVFKVTHRITGQVMALKMN-----TMTSNRHNMLREVQLLNRLQ 308
Query: 190 HPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTAT----YITELANALS 245
H NILR G +++ + EY P G + Q L K DE+ T LA L
Sbjct: 309 HANILRFMGVCVHEGQLHALTEYIPSGNLE---QLLEKKDEELPWTQRIQLTLGLARGLD 479
Query: 246 YCHSKRVIHRDIKPENLLL----GSAGELKIADFGWSVHAP---SSRRTTLCGTLDYLPP 298
Y HS R IHRD+ +N+L+ IADFG + P + G+ ++ P
Sbjct: 480 YLHSTRFIHRDLTSKNILIRREDNHGYHAVIADFGLATKIPDPLDKEKLPTVGSPYWMAP 659
Query: 299 EMIEGRMHDEKVDLWSLGVLCYEFLVGKP 327
E++ G ++E+ DL+S+G++ E P
Sbjct: 660 EVLNGHFYNERADLFSVGIIMCEITARIP 746
>17975
Length = 449
Score = 85.1 bits (209), Expect = 4e-17, Method: Compositional matrix adjust.
Identities = 51/137 (37%), Positives = 80/137 (58%), Gaps = 2/137 (1%)
Frame = +3
Query: 144 FGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDA 203
F V LAR + +A+KV+ K +L++ H L +EV ++HPN++RLY
Sbjct: 6 FAVVKLARHVFTGEKVAVKVIDKTKLDEVSRSH-LFQEVRCMKLVQHPNVVRLYEVIDTQ 182
Query: 204 TRVYLILEYAPLGTVYRELQKLSKFDEQRTAT-YITELANALSYCHSKRVIHRDIKPENL 262
T++YLILE G +Y + + S E++ A Y ++ A+SYCH V+HRD+KPEN+
Sbjct: 183 TKLYLILELGDGGDMYDYIMRHSGGLEEKLAKRYFRQIVEAISYCHKLHVVHRDLKPENV 362
Query: 263 LLGSA-GELKIADFGWS 278
+ G +K+ DFG+S
Sbjct: 363 VFFEKPGLVKLTDFGFS 413
>31885
Length = 529
Score = 84.3 bits (207), Expect = 7e-17, Method: Compositional matrix adjust.
Identities = 48/158 (30%), Positives = 81/158 (51%), Gaps = 6/158 (3%)
Frame = -2
Query: 182 VEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELA 241
V++ + L HP ++ L+ F D ++++++ G + +Q+ F E Y+ +LA
Sbjct: 519 VDMLTRLDHPFLVNLWYAFQDEEDLFMVVDLFLGGDLRYHMQQEVSFREDCVKFYLCQLA 340
Query: 242 NALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSR-RTTLCGTLDYLPPEM 300
L Y S++++HRDIKP+N+LL G + DF + T+ GT Y+ PE+
Sbjct: 339 LVLDYLRSQKIVHRDIKPDNILLDEQGHCHVTDFNIATQLEDDELATSTSGTRPYMAPEV 160
Query: 301 I-----EGRMHDEKVDLWSLGVLCYEFLVGKPPFEANT 333
E R + VD WSLGV +E L + PF ++
Sbjct: 159 YGVAINERRGYGFPVDWWSLGVSLFELLKKRRPFSVHS 46
>27546
Length = 426
Score = 82.8 bits (203), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 42/120 (35%), Positives = 70/120 (58%)
Frame = -1
Query: 159 LALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTV 218
LA K++ KA+ V+ RE+EI + L HPNI++++ ++++ + YA G +
Sbjct: 396 LACKIIDKAKAPIDFVKKFFPRELEILTRLDHPNIIQIHSILQRGPKIFIFMRYAEKGDM 217
Query: 219 YRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS 278
++K DE +T + ++A AL Y HS + HRD+K EN+LL +KIADFG++
Sbjct: 216 LSHIKKTGPIDEAQTKVWFFQMAKALQYLHSHDIAHRDLKCENILLSKRLNVKIADFGFA 37
>00486
Length = 797
Score = 82.0 bits (201), Expect = 3e-16, Method: Compositional matrix adjust.
Identities = 35/84 (41%), Positives = 53/84 (63%)
Frame = -2
Query: 288 TLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFT 347
T CGT++Y+ PE++ H + VD WSLG L Y+ L G PPF A ++T +I + +
Sbjct: 781 TFCGTIEYMAPEILTRTGHGKAVDWWSLGALMYDMLTGSPPFTAENRKKTIDKILKGKLN 602
Query: 348 FPDFVTEGARDLISRLLKHNPSQR 371
P ++T AR LI +LL+ NP++R
Sbjct: 601 LPPYLTNEARGLIKKLLRKNPAER 530
>21079
Length = 878
Score = 81.6 bits (200), Expect = 6e-16, Method: Compositional matrix adjust.
Identities = 42/148 (28%), Positives = 79/148 (53%), Gaps = 4/148 (2%)
Frame = +1
Query: 190 HPNILRLYGYFHDATRVYLILEYAPLGTVY-RELQKLSKFDEQRTATYITELANALSYCH 248
HP +L L+ F + L++E+ G ++ R ++ E+ ++ ++ + + Y H
Sbjct: 1 HPKLLMLWDAFEAPRTMVLVMEFVGAGELFERVIRDDFVLTERDCVHFVRQICSGVGYMH 180
Query: 249 SKRVIHRDIKPENLLLGS--AGELKIADFGWS-VHAPSSRRTTLCGTLDYLPPEMIEGRM 305
++ ++H D+KPEN+L S + ++KI DFG + + P L GT +++ PE++
Sbjct: 181 TQSILHLDLKPENVLCVSDNSNQIKIIDFGLARFYKPGDSLQVLFGTPEFIAPEVVNYDE 360
Query: 306 HDEKVDLWSLGVLCYEFLVGKPPFEANT 333
+ D+WS+GV+CY L G P T
Sbjct: 361 INFTTDMWSIGVICYILLSGLSPSRVTT 444
>00392
Length = 668
Score = 80.5 bits (197), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 48/175 (27%), Positives = 91/175 (52%), Gaps = 9/175 (5%)
Frame = +3
Query: 177 QLRREVEIQSHLRHPNILRLYGYFHDATR-----VYLILEYAPLGTVYRELQKLSKFDEQ 231
+ + E E+ L+HPNI+R + Y+ + + L+ E GT+ L++ K + +
Sbjct: 69 RFKEEAEMLKELQHPNIVRFFDYWEEHNHRNRKVIILVTELMTSGTLKTYLKRFKKPNVK 248
Query: 232 RTATYITELANALSYCHSKR--VIHRDIKPENLLL-GSAGELKIADFGWSVHAPSSRRTT 288
+ ++ L + H++ VIHRD+K +N+ + G G +KI D G + S +
Sbjct: 249 ILKNWCRQVLKGLYFLHTRTPPVIHRDLKCDNIFITGPTGSVKIGDLGLATLKNQSFAKS 428
Query: 289 LCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPF-EANTYQETYKRIS 342
+ GT +++ PEM E +DE VD+++ G+ E + P+ E + + YKR++
Sbjct: 429 VIGTPEFMAPEMYEEH-YDEAVDVYAFGMCMLEMASSEYPYSECSNAAQIYKRVT 590
>01966
Length = 1735
Score = 79.0 bits (193), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 42/135 (31%), Positives = 70/135 (51%), Gaps = 4/135 (2%)
Frame = -1
Query: 173 GVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEY--APLGTVYRELQKLSKFDE 230
GV RE+ + LRH NI+ L + R++L+ E+ L + + D
Sbjct: 1588 GVPSSAIREIAMLRELRHTNIVCLEDVIMEDERLFLVFEFLSMDLKMYIDKFPEGVVLDR 1409
Query: 231 QRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGW--SVHAPSSRRTT 288
+ +Y+ ++ +++CH +R++HRD+KP+NLL+ G +KIADFG + P T
Sbjct: 1408 RLVKSYVFQIVTGINFCHQRRIVHRDLKPQNLLINHTGAIKIADFGMARTFALPVRAYTH 1229
Query: 289 LCGTLDYLPPEMIEG 303
TL Y PE++ G
Sbjct: 1228 EVVTLWYRAPEILMG 1184
>19761
Length = 473
Score = 76.3 bits (186), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 40/142 (28%), Positives = 77/142 (54%), Gaps = 4/142 (2%)
Frame = -3
Query: 230 EQRTATYITELANALSYCHSKR--VIHRDIKPENLLLGSAGELKIADFGWS--VHAPSSR 285
E+ ++ + A+AL+Y H+ ++HRD+KP+N+ + G++++ D G + + P+
Sbjct: 426 ERLIVCWLMQTASALNYMHTHTPVILHRDLKPQNIYVTEKGDVRLGDLGLARKLTGPADF 247
Query: 286 RTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVE 345
T+ GT+ YL PE++ + ++ K D+WSLG + Y+ K E + + +
Sbjct: 246 ATSQVGTIMYLSPEILSQQPYNSKSDIWSLGCVFYDITGKKGSDEMGVMFLLVQVMGGRK 67
Query: 346 FTFPDFVTEGARDLISRLLKHN 367
PD ++ RD ISR+L +
Sbjct: 66 LPLPDHYSQEFRDTISRMLTKD 1
>19094
Length = 898
Score = 70.1 bits (170), Expect(2) = 6e-14, Method: Compositional matrix adjust.
Identities = 39/103 (37%), Positives = 57/103 (55%), Gaps = 2/103 (1%)
Frame = +1
Query: 230 EQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS--VHAPSSRRT 287
E+ AT + L Y HS+R IHRDIK N+LL + G K+ADFG + + ++R
Sbjct: 55 EREIATILYYTLKGL*YLHSRRKIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRN 234
Query: 288 TLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFE 330
T+ GT ++ PE+I+ +D D+WSLG+ E G E
Sbjct: 235 TVIGTPYWMAPEVIQEIGYDCVADIWSLGITALEMAEGNLHME 363
Score = 24.6 bits (52), Expect(2) = 6e-14, Method: Compositional matrix adjust.
Identities = 12/38 (31%), Positives = 19/38 (50%)
Frame = +3
Query: 346 FTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWI 383
F PD + D +S+ L NP R ++L+H +I
Sbjct: 417 FRQPDKWSTEFIDFVSKCLVKNPENRATAVDLLQHDFI 530
>26560
Length = 398
Score = 74.7 bits (182), Expect = 7e-14, Method: Composition-based stats.
Identities = 40/131 (30%), Positives = 67/131 (51%), Gaps = 1/131 (0%)
Frame = -1
Query: 218 VYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGW 277
++ L + F E+ Y E+ L + HS+ V++RD+KP N+LL G ++I+D G
Sbjct: 395 LHYHLSQHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGL 216
Query: 278 SVHAPSSRRTTLCGTLDYLPPE-MIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQE 336
+ R GT Y+ PE +++G+ +D D +S G + Y+ L G PF + +
Sbjct: 215 ACDFSKKRPHASVGTHGYMAPEVLMKGQSYDSSADWFSFGCMLYKLLKGHSPFR--QHNQ 42
Query: 337 TYKRISRVEFT 347
RI R+ T
Sbjct: 41 GQARIDRMTMT 9
>29581
Length = 1278
Score = 72.0 bits (175), Expect = 4e-13, Method: Compositional matrix adjust.
Identities = 63/235 (26%), Positives = 101/235 (42%), Gaps = 38/235 (16%)
Frame = -2
Query: 187 HLRHPNILRL----YGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELAN 242
+LRH NI++L G D+ ++L++EY + F E + + +L
Sbjct: 1187 NLRHQNIVQLQEVVVGKSLDS--LFLVMEYCEQDLASLLDNMPAPFSESQVKCIVLQLLK 1014
Query: 243 ALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVH--APSSRRTTLCGTLDYLPPEM 300
L Y H +IHRD+K NLL+ G +KIADFG + + P T TL Y PE+
Sbjct: 1013 GLRYLHEAFIIHRDLKVSNLLMTDKGCVKIADFGLARNYGKPQKPMTPKVVTLWYRAPEL 834
Query: 301 IEG-RMHDEKVDLWSLGVLCYEFLVGKPPFEANT-------------------------- 333
+ G + H +D+WS G + E L KP +
Sbjct: 833 LFGSKTHSTAIDMWSAGCILGELLGHKPLMPGRSDLQQIELIMELLGTPNDTIWPGFSQL 654
Query: 334 ---YQETYKR--ISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWI 383
Q T K+ + + TFP +++E L++ L ++P +R + LEH +
Sbjct: 653 PAFEQFTLKKQPYNNLRHTFP-WLSESGIRLLNGLFMYHPQKRATAEDCLEHSYF 492
>20152
Length = 445
Score = 68.9 bits (167), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 32/96 (33%), Positives = 50/96 (52%), Gaps = 1/96 (1%)
Frame = +1
Query: 298 PEMIEGRMHDE-KVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGA 356
PE++ G +D VD+WSLGV+ Y +VG+ PF+ ET I + P ++
Sbjct: 1 PEILLGDSYDAPAVDVWSLGVILYMLVVGEAPFQEANDSETLTMIMDCRYQIPPHISHKC 180
Query: 357 RDLISRLLKHNPSQRPMLREVLEHPWITANSSKPSN 392
+DLI ++L+ P R L +L HPW+ P+
Sbjct: 181 QDLIEKMLQREPVDRASLPHILAHPWLNDGDLTPTT 288
>27405
Length = 532
Score = 67.8 bits (164), Expect = 7e-12, Method: Compositional matrix adjust.
Identities = 47/175 (26%), Positives = 84/175 (48%), Gaps = 5/175 (2%)
Frame = -3
Query: 144 FGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLR----HPNILRLYGY 199
FG VY R+ + + A+K L K +++ G E E + S + P I+ +
Sbjct: 527 FGEVYGCRKADTGKMYAMKCLDKKRIKMKGGETLALNERIMLSLVSTGEGSPFIVCMTYA 348
Query: 200 FHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKP 259
F ++ IL+ G ++ L + F E+ Y E+ L + HS+ V++RD+KP
Sbjct: 347 FQTPEKLCFILDLMNGGDLHYHLSQHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKP 168
Query: 260 ENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPE-MIEGRMHDEKVDLW 313
N+LL G ++I+D G + + GT Y+ PE +++G+ +D D +
Sbjct: 167 ANILLDENGHVRISDLGLACDFSKKKPHASVGTHGYMAPEVLMKGQAYDSSADWF 3
>26711
Length = 405
Score = 65.9 bits (159), Expect = 3e-11, Method: Composition-based stats.
Identities = 39/132 (29%), Positives = 72/132 (54%), Gaps = 8/132 (6%)
Frame = -2
Query: 237 ITELANALSYCHSKRVIHRDIKPENLLLG--SAGELKIADFGWSVHAPSSRRTTLC-GTL 293
+ ++ + L + H++ V+H D+KP NLLL +++ DFG + + T L GT
Sbjct: 398 VKQVLDILQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARKLYPPQETFLNHGTP 219
Query: 294 DYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTF---PD 350
+ PE ++ + D+W +GVL Y L G+ PF+A++ E+ K+ +++F P
Sbjct: 218 GFTSPEALDVKPISTASDVWGVGVLAYILLSGQSPFQADSATESLKKTQTCDWSFDVCPS 39
Query: 351 F--VTEGARDLI 360
F +++ A+D I
Sbjct: 38 FSNMSQDAKDFI 3
>19301
Length = 712
Score = 65.1 bits (157), Expect = 5e-11, Method: Compositional matrix adjust.
Identities = 33/101 (32%), Positives = 56/101 (55%), Gaps = 2/101 (1%)
Frame = +2
Query: 180 REVEIQS--HLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYI 237
+E +I++ L HPNI+ G A +I+EY P G +Y L+ + +
Sbjct: 410 KETDIRNLRKLNHPNIISFKGVCTQAPCYCIIMEYCPYGQLYEVLRDGKEIPPALVLDWS 589
Query: 238 TELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS 278
++A+ ++Y HS ++IHRD+K N+L+ +KI+DFG S
Sbjct: 590 KQIASGMNYLHSHKIIHRDLKSPNVLVAKNDVVKISDFGTS 712
>38560
Length = 479
Score = 64.7 bits (156), Expect = 6e-11, Method: Compositional matrix adjust.
Identities = 33/111 (29%), Positives = 58/111 (52%), Gaps = 1/111 (0%)
Frame = -3
Query: 287 TTLCGTLDYLPPEMIEGRMH-DEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVE 345
TT CG+ Y PE+I G + + D+WS+GVL Y L G PF+ ++ + +
Sbjct: 411 TTCCGSPAYAAPELISGLEYLGSEADIWSMGVLLYALLCGYLPFDDEKXSHL*QKNQKRK 232
Query: 346 FTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQNK 396
P++++E L+ +L+ +PS R +R +L+H W+ + P +K
Sbjct: 231 DEVPEWLSEDTTKLLEGMLQTDPSHRITIRRLLDHHWLNQGFNVPVEWASK 79
>14477
Length = 493
Score = 63.9 bits (154), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 44/142 (30%), Positives = 73/142 (51%), Gaps = 2/142 (1%)
Frame = -1
Query: 139 LGKGKFGNVY--LAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRL 196
LG G FG+V + R + +A+KVL A L+ + V+ +L +E E+ + H +I+RL
Sbjct: 466 LGAGNFGSVMKGVCRLDDREIPVAIKVLKNADLDPS-VQSELIKEAEVMKKMDHMHIVRL 290
Query: 197 YGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRD 256
G T + L+LE A LG + + L K + +++ + Y + + +HRD
Sbjct: 289 IGLCEGET-MMLVLELAKLGPLNKFLPKNKHLPLWNILELMWQVSQGMEYLEANKFVHRD 113
Query: 257 IKPENLLLGSAGELKIADFGWS 278
+ N+LL KI+DFG S
Sbjct: 112 LAARNILLCDEHFAKISDFGMS 47
>04852
Length = 1462
Score = 63.9 bits (154), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 40/151 (26%), Positives = 75/151 (49%), Gaps = 5/151 (3%)
Frame = +1
Query: 235 TYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTL- 293
+Y ++A + + S++ IHRD+ N+L+ LKIADFG S ++ + G L
Sbjct: 337 SYAFQIARGMEFLASRKCIHRDLAARNVLVTEEHVLKIADFGLSRTGDYYKKRS-GGRLP 513
Query: 294 -DYLPPEMIEGRMHDEKVDLWSLGVLCYE-FLVGKPPFEANTYQETYKRISRVEFTF--P 349
++ PE + + K D+WS GV+ +E F +G P+ + +E Y ++ + P
Sbjct: 514 VKWMAPEALFDMRYTTKSDVWSFGVVLWEIFSLGGMPYASIPNEELYSKLLDDAYRMPRP 693
Query: 350 DFVTEGARDLISRLLKHNPSQRPMLREVLEH 380
+ + ++ R + PS RP +++ H
Sbjct: 694 ELASGNLYAIMERCWLNRPSDRPEFSQLVGH 786
>06358
Length = 1517
Score = 63.5 bits (153), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 65/273 (23%), Positives = 121/273 (44%), Gaps = 40/273 (14%)
Frame = +3
Query: 140 GKGKFGNVYLAREKQSK-----FILALKVLFK-AQLEKAGVEHQLRREVEIQSHLRHPNI 193
G G V+ A +K +K F+ K + + ++ ++ + LR V+ + LRHP I
Sbjct: 33 GPGLLWKVFAASKKSTKEEASVFVFEKKSVDRYSRRDREAIVEVLRVGVQQLTKLRHPKI 212
Query: 194 LRLYGYFHD-------------ATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITEL 240
L + + A+ ++ + + + TV +ELQ +D + + ++
Sbjct: 213 LAVINPLEESRETLAFATEPVFASLANVLGDLSSIXTVPKELQDYQLYDVE-IKHGLLQV 389
Query: 241 ANALSYCHSK-RVIHRDIKPENLLLGSAGELKIADFGWSVHA--PSSR---------RTT 288
AL + H+ +++HR++ PE ++L G K+A + + V + P S R+
Sbjct: 390 TEALGFLHNDAKMMHRNVCPEAIMLTKLGSWKLAGYEFCVRSSDPQSTDPSYPFYEWRSD 569
Query: 289 LCGT----LDYLPPEMIEGRMHDEKVDLWSLGVLCYE-FLVGKPPFEAN----TYQETYK 339
+ LD++ PE + D++SLG+L Y F GKP FE N ++ +
Sbjct: 570 IAPVTQPHLDFMAPEYVLTMQCGTGSDMFSLGLLVYSVFAKGKPLFECNGELSAFKSNAE 749
Query: 340 RISRVEFTFPDFVTEGARDLISRLLKHNPSQRP 372
+ + + V E RD + LL P+ RP
Sbjct: 750 ELRHMRVSLLGVVPEDLRDHVKLLLNIEPAVRP 848
>04138
Length = 800
Score = 63.5 bits (153), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 51/177 (28%), Positives = 72/177 (40%), Gaps = 40/177 (22%)
Frame = +1
Query: 244 LSYCHSKRVIHRDIKPENLLLGSAGELKIADFG----WSVHAPS-SRRTTLCGTLDYLPP 298
L Y H +++HRD+K N+L+ G LK+ADFG +SV+ +R T TL Y PP
Sbjct: 52 LYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRPP 231
Query: 299 EMIEG-RMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGAR 357
E++ G R + +D W G + E P + T Q I+++ + V G
Sbjct: 232 ELLLGDRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQNQLTLITQLCGSITPEVWPGVT 411
Query: 358 ----------------------------------DLISRLLKHNPSQRPMLREVLEH 380
DL RLLK +PSQR E L H
Sbjct: 412 QLSMYHQIKGALAAGRKNIIRDRFARILKDPYGLDLFERLLKMDPSQRISADEALNH 582
>21808
Length = 1011
Score = 63.2 bits (152), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 43/166 (25%), Positives = 73/166 (43%), Gaps = 5/166 (3%)
Frame = +1
Query: 181 EVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYI-TE 239
E +I LRHP +++LY +++I E G++ LQ + + I +
Sbjct: 82 EAQIMKKLRHPKLIQLYAVCTQDDPIFIITELMKNGSLLEFLQGKGRVLKLPALIDIGAQ 261
Query: 240 LANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGT---LDYL 296
+A ++Y S+ IHRD+ N+L+ +KIADFG + G + +
Sbjct: 262 IACGMAYLESQNYIHRDLAARNILVSDNNTVKIADFGLARVIKEDEYEARVGARFPIKWT 441
Query: 297 PPEMIEGRMHDEKVDLWSLGVLCYEFLV-GKPPFEANTYQETYKRI 341
PE K D+WS G+L E + G+ P+ T E ++
Sbjct: 442 APEAANYNRFTIKSDVWSFGILLTETVTYGRVPYPGMTNAEVLHQV 579
>00715
Length = 1788
Score = 61.6 bits (148), Expect = 5e-10, Method: Compositional matrix adjust.
Identities = 47/177 (26%), Positives = 76/177 (42%), Gaps = 33/177 (18%)
Frame = +1
Query: 188 LRHPNILRLYGY-----FHDATRVYLILEYAP---LGTVYRELQKLSKFDEQRTATYITE 239
LRH N++ + G F D +L +EY L T+ + Q+ D + +
Sbjct: 97 LRHVNVVSILGATSLHRFEDGA--WLAMEYVGPLNLQTILNDHQQ--DIDSSMRLSLALQ 264
Query: 240 LANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVH------------------- 280
+A L Y HS ++H D+KP N LL +L+IADFG H
Sbjct: 265 MARGLHYLHSINIVHLDLKPANCLLTRDLKLRIADFG-CCHQLTPTGLDMGEREGGMAGN 441
Query: 281 ------APSSRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEA 331
+ + L GTL Y PE+++G + D++SLG+ ++ + P+E
Sbjct: 442 ELELTPVQGAWKNELAGTLAYRAPELLKGLQPSVRSDVYSLGITLWQMCTRQGPYEG 612
>14116
Length = 1017
Score = 61.2 bits (147), Expect = 6e-10, Method: Compositional matrix adjust.
Identities = 56/217 (25%), Positives = 96/217 (44%), Gaps = 24/217 (11%)
Frame = -1
Query: 131 EDFEIGRPLGKGKFGNV---YLAR-EKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQS 186
E +G +GKG FG V +L E++ ++A+K L RE+E+QS
Sbjct: 636 EFLTMGEEIGKGNFGCVKRGFLTLPEQKGDILVAVKTLHNNN----------PREIELQS 487
Query: 187 HLR---------HPNILRLYGY---FHDATRVYL-ILEYAPLGTVYRELQKLSKFDEQRT 233
L+ H N+L L G D V L +++ L T R+ Q +
Sbjct: 486 FLQEALIMKDFHHSNVLTLIGICLNLDDMPLVVLPFMKHGDLLTYIRDDQHQPTIKD--L 313
Query: 234 ATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS-------VHAPSSRR 286
Y ++A + Y + +HRD+ N +L +K+ADFG + ++ +++
Sbjct: 312 IMYGVDIARGMDYLAGLKFVHRDLAARNCMLDEDFHVKVADFGLARDIYEKEYYSSENKK 133
Query: 287 TTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFL 323
L + ++ E +E +D K D+WS GV+ +E L
Sbjct: 132 AKL--PVKWMALESLEKGNYDSKTDVWSYGVVLWELL 28
>28157
Length = 400
Score = 61.2 bits (147), Expect = 8e-10, Method: Compositional matrix adjust.
Identities = 39/104 (37%), Positives = 57/104 (54%), Gaps = 7/104 (6%)
Frame = +3
Query: 180 REVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLS---KFDEQRTATY 236
+E++ S + HPNI+ LYG D V L++EYA G++Y L ++ +
Sbjct: 57 QELKQLSRVSHPNIVCLYGACRDHP-VCLVMEYAEGGSLYNVLHGSGPQPQYTAAHAMNW 233
Query: 237 ITELANALSYCHS---KRVIHRDIKPENLLLGSAG-ELKIADFG 276
+ + A + Y H K +IHRD+KP NLLL G +LKI DFG
Sbjct: 234 LLQCALGVEYLHGMKPKALIHRDLKPPNLLLIQCGTKLKICDFG 365
>12672
Length = 773
Score = 60.8 bits (146), Expect = 9e-10, Method: Compositional matrix adjust.
Identities = 45/161 (27%), Positives = 69/161 (42%), Gaps = 24/161 (14%)
Frame = +3
Query: 241 ANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTT------LCGTLD 294
A+ + Y + +HRDIK N+LL S K+ DF V APS T + GT
Sbjct: 21 ASGIQYLNDNGHVHRDIKTANILLDSEYTAKVGDFATVVSAPSGEGKTVQNASVVIGTAA 200
Query: 295 YLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTY------------------QE 336
YL PE I + K+D +S GV+ E + G A Y +E
Sbjct: 201 YLAPEAIHFDVS-TKLDSYSFGVVLLEVITG---LVAQDYSREERTLSSHIMENVEEPEE 368
Query: 337 TYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREV 377
+ + + T+PD + D+ R L + QRP ++++
Sbjct: 369 IHDFVDQSAGTWPDGAVDKLYDISMRCLNLSKKQRPNVKDI 491
>07940
Length = 1336
Score = 60.8 bits (146), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 36/100 (36%), Positives = 54/100 (54%), Gaps = 5/100 (5%)
Frame = -3
Query: 235 TYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS--VHAPSSRRTTLCGT 292
+Y ++A + Y SK+ IHRD+ N+L+ LKIADFG + + R T G
Sbjct: 335 SYAYQVARGMEYLASKQCIHRDLAARNVLVAEEYVLKIADFGLTRNLQQFDYYRKTTDGR 156
Query: 293 L--DYLPPEMIEGRMHDEKVDLWSLGVLCYE-FLVGKPPF 329
L ++ PE + R + K D+WS GVL +E F +G P+
Sbjct: 155 LPVKWMAPEALFDRKYTSKSDVWSYGVLLWEIFTLGGNPY 36
Score = 34.3 bits (77), Expect = 0.088, Method: Compositional matrix adjust.
Identities = 28/95 (29%), Positives = 49/95 (51%), Gaps = 7/95 (7%)
Frame = -3
Query: 131 EDFEIGRPLGKGKFGNVYLAREKQSKF------ILALKVLFKAQLEKAGVEHQLRREVEI 184
E +G LG+G FG V + E F +A+K+L + ++ ++ L RE+E+
Sbjct: 842 ERLVLGDRLGEGAFGLV-MKGEAMGIFKDNNSVTVAVKMLKEDATDREMMD--LIREMEM 672
Query: 185 QSHL-RHPNILRLYGYFHDATRVYLILEYAPLGTV 218
+ +H NI+ L G +Y+I+E+AP G +
Sbjct: 671 MKVIGKHKNIINLLGCCTQRGALYVIVEFAPHGNL 567
>03508
Length = 1463
Score = 60.8 bits (146), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 31/109 (28%), Positives = 57/109 (52%), Gaps = 3/109 (2%)
Frame = +1
Query: 223 QKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAG-ELKIADFGWS-VH 280
Q F + Y+ EL AL +CHS ++HRD+KP N+++ +L++ D+G + +
Sbjct: 847 QLYQTFTDYDIRFYLYELMKALDFCHSMGIMHRDVKPHNVMIDHENKKLRLIDWGLAEFY 1026
Query: 281 APSSRRTTLCGTLDYLPPE-MIEGRMHDEKVDLWSLGVLCYEFLVGKPP 328
P + + PE +++ +M+D +D+WSLG + + K P
Sbjct: 1027HPGMEYNVRVASRYFKGPELLLDYQMYDYSLDMWSLGCMFASMIFRKEP 1173
>26009
Length = 886
Score = 40.8 bits (94), Expect(2) = 3e-09, Method: Compositional matrix adjust.
Identities = 17/49 (34%), Positives = 30/49 (61%)
Frame = +3
Query: 216 GTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLL 264
GT ++ + + + +L +AL + HSK+++HRDIKPEN+L+
Sbjct: 666 GTCLTPSRRNKACGSREAKSVMKQLVSALDFMHSKQLVHRDIKPENVLI 812
Score = 38.1 bits (87), Expect(2) = 3e-09, Method: Compositional matrix adjust.
Identities = 26/91 (28%), Positives = 47/91 (51%), Gaps = 2/91 (2%)
Frame = +2
Query: 131 EDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLR- 189
E +++ + LG+G +G V LAR + + +ALK+L K+ + + +RE ++ L
Sbjct: 416 EHYDVCKELGRGTYGKVVLARCRHTGTQVALKLLPKSCTKL----REFQREFQLSYFLSP 583
Query: 190 HPNILRLYGY-FHDATRVYLILEYAPLGTVY 219
H NI+ Y F + E+A LG ++
Sbjct: 584 HANIIDTYNVAFQTRSSYVFAQEHAVLGDLF 676
>12786
Length = 460
Score = 58.9 bits (141), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 37/127 (29%), Positives = 54/127 (42%), Gaps = 24/127 (18%)
Frame = -3
Query: 228 FDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRT 287
D Y E+ A+ H++ VIH D+KP N +L AG LK+ DFG + + +
Sbjct: 419 LDRMMIKFYWREMLRAVKALHNEGVIHSDLKPANFML-VAGNLKLIDFGIANTLQQDKTS 243
Query: 288 TL----CGTLDYLPPEMIEGRMHDE--------------------KVDLWSLGVLCYEFL 323
L GT Y+ PE I D + D+WSLG + Y +
Sbjct: 242 VLKDSRVGTPSYMSPEAIMAACDDSADDSMEEDGHRTKPKYKVGVRSDVWSLGCILYNMV 63
Query: 324 VGKPPFE 330
G+ PF+
Sbjct: 62 YGRTPFQ 42
>18663
Length = 600
Score = 57.8 bits (138), Expect = 7e-09, Method: Compositional matrix adjust.
Identities = 32/112 (28%), Positives = 52/112 (46%), Gaps = 15/112 (13%)
Frame = +2
Query: 287 TTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEA---------NTYQET 337
+T CGT +Y+ PE++ G + VD W+LGVL YE L G+ PF+ NT
Sbjct: 2 STFCGTPNYIAPEILRGEDYGFSVDWWALGVLLYEMLAGRSPFDIAGASENPDQNTEDYL 181
Query: 338 YKRISRVEFTFPDFVTEGARDLISRLLKHNPSQR------PMLREVLEHPWI 383
++ I P ++ A ++ L NP+ R +++ HP+
Sbjct: 182 FQVILEKTIRIPRSLSVKAASVLKGFLNKNPADRLGCHRESAFMDIVNHPFF 337
>28638
Length = 1458
Score = 55.8 bits (133), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 41/132 (31%), Positives = 60/132 (45%), Gaps = 5/132 (3%)
Frame = -1
Query: 203 ATRVYLILEYAP-LGTVYRELQKLSKFDEQRTATYITELANALSYCHS--KRVIHRDIKP 259
AT L +P + T Q L T + +L AL + + +IH D+KP
Sbjct: 924 ATTCVWCLSCSPTISTTCYATQTLEGVSLNLTRKFAQQLCTALLFLATPEMNIIHCDLKP 745
Query: 260 ENLLLGSA--GELKIADFGWSVHAPSSRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGV 317
EN+LL + +KI DFG S R + Y PE++ G +D +D+WSLG
Sbjct: 744 ENILLCNPKRSAIKIVDFGSSCQL-GQRIYQYIQSRFYRSPEVLLGVPYDLAIDMWSLGC 568
Query: 318 LCYEFLVGKPPF 329
+ E G+PP
Sbjct: 567 ILVEMHTGEPPL 532
>02638
Length = 1490
Score = 53.1 bits (126), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 27/104 (25%), Positives = 52/104 (50%), Gaps = 5/104 (4%)
Frame = +1
Query: 289 LCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFT- 347
L GT+ ++ PE++ G + D+WS+G + E +PP+ ++ I ++ +
Sbjct: 16 LLGTIAFMAPEVLRGESYGRACDVWSVGCVMIEMCTCRPPWNSHDISNHLALIFKIASSV 195
Query: 348 ----FPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANS 387
P+ ++ RDL+ R L+ + RP +++L HP T S
Sbjct: 196 DPPPIPENMSPPVRDLMLRCLEQDSDFRPSAKDLLMHPLFTKYS 327
>11185
Length = 473
Score = 52.4 bits (124), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 30/110 (27%), Positives = 48/110 (43%), Gaps = 24/110 (21%)
Frame = +1
Query: 240 LANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFG----------------------W 277
L L Y HS ++ D++P +LL ++G LK ADFG W
Sbjct: 28 LVTGLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQW 207
Query: 278 SVHAPSS--RRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVG 325
++ + ++ G+ Y+ PE+ +G DLW+LG + YE G
Sbjct: 208 NIQSAEEMMKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSG 357
>25019
Length = 730
Score = 52.4 bits (124), Expect = 4e-07, Method: Compositional matrix adjust.
Identities = 25/59 (42%), Positives = 35/59 (59%), Gaps = 2/59 (3%)
Frame = +3
Query: 260 ENLLLGSAGELKIADFGWSVHAPSSRRTT--LCGTLDYLPPEMIEGRMHDEKVDLWSLG 316
EN+LL G +K+ DFG A + R T CGT++Y+ PE++ H + VD WSLG
Sbjct: 261 ENVLLDKDGHVKLTDFGLCKEAITGTRVTHTFCGTIEYMAPEILTRTGHGKAVDWWSLG 437
>29590
Length = 320
Score = 38.9 bits (89), Expect(2) = 1e-06, Method: Composition-based stats.
Identities = 17/41 (41%), Positives = 24/41 (58%)
Frame = +3
Query: 289 LCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPF 329
+ GT DY+ PE+++ + D+WSLGVL Y L PF
Sbjct: 54 IIGTPDYVAPEVLDYEPLSIQTDMWSLGVLSYVMLTACSPF 176
Score = 31.2 bits (69), Expect(2) = 1e-06, Method: Composition-based stats.
Identities = 16/41 (39%), Positives = 24/41 (58%), Gaps = 4/41 (9%)
Frame = +2
Query: 335 QETYKRISRVEFTFPD----FVTEGARDLISRLLKHNPSQR 371
QET+ IS+V+ FPD ++ A+D I +LL +P R
Sbjct: 191 QETFCNISQVKLDFPDDLFSHISPHAKDFIKKLLVKDPRHR 313
>27274
Length = 396
Score = 49.7 bits (117), Expect = 2e-06, Method: Composition-based stats.
Identities = 30/97 (30%), Positives = 45/97 (46%), Gaps = 12/97 (12%)
Frame = -1
Query: 299 EMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEAN------------TYQETYKRISRVEF 346
E++ G+ H VD+WSLG+L +E L G PFE Y + + SR
Sbjct: 375 ELLRGQQHGPTVDMWSLGILLHELLSGHVPFEPERGSRQMARNMMAVYAQIIRGSSRDVC 196
Query: 347 TFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWI 383
T GA D + RL++ ++R ++ HPWI
Sbjct: 195 DGLALSTHGA-DFLRRLVQLEDTKRLTSQQAFSHPWI 88
>31120
Length = 439
Score = 48.9 bits (115), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 33/99 (33%), Positives = 53/99 (53%), Gaps = 6/99 (6%)
Frame = +1
Query: 299 EMIEGRMHDEKV-DLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTF----PDFVT 353
E++ G +D K+ D WSLGV+ + L GK PF+ + + + +++F D V+
Sbjct: 1 EVVCGVPYDPKMADAWSLGVILFIMLNGKMPFDDSNLNKLLEDQRSKKYSFRRKLQDLVS 180
Query: 354 EGARDLISRLLKHNPSQRPMLREVLEHPWI-TANSSKPS 391
AR +S LL+ N + R L EVL W+ T + +PS
Sbjct: 181 PNARSTVSVLLEPNSAMRWDLNEVLNCQWLQTIDEPRPS 297
>37602
Length = 804
Score = 48.5 bits (114), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 32/99 (32%), Positives = 46/99 (46%), Gaps = 3/99 (3%)
Frame = -1
Query: 189 RHPNILRLYGYFHDATR---VYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALS 245
R NI GYF R +++ +EY G++ E + A E L
Sbjct: 354 RIVNIQTFVGYFDSYLRREKLWIAMEYCGGGSMQDIYHVTGPLTEPQIAFVCRETLKGLH 175
Query: 246 YCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSS 284
Y H + +HRDIK N+LL G++K+ADF W V + S
Sbjct: 174 YLHRRGKMHRDIKGANILLTEEGDVKLADF-WRVSSNHS 61
>07833
Length = 1504
Score = 48.1 bits (113), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 45/213 (21%), Positives = 88/213 (41%), Gaps = 21/213 (9%)
Frame = -3
Query: 188 LRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKF--DEQRTATYITELANALS 245
HPN+L + + + LI ++ P G++Y L S D+ ++ + ++A +
Sbjct: 1448 FNHPNVLPVLACCNQPPNLVLISQFMPFGSLYNTLHGESGIVVDQNQSLRFAMDIARGME 1269
Query: 246 YCHSKRVIHRDIKPE--NLLLGS---------AGELKIADFGWSVHAPSSRRTTLCGTLD 294
+ HS ++P N LL S + +AD+ +S H +
Sbjct: 1268 FLHS-------MEPTIPNFLLTSKHVMIDEDLTARINMADYCFSFHEKGKVYSP-----A 1125
Query: 295 YLPPEMIEGRMHD---EKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISR--VEFTFP 349
++ PE ++ R D D+WS +L +E + PF + E +++ + + P
Sbjct: 1124 WMAPEALQRRPDDINTRAADMWSFAILMWELETREVPFAELSSMEVGMKVALEGLRISIP 945
Query: 350 DFVTEGARDLISRLLKHNPSQRP---MLREVLE 379
++ LI + P +RP M+ +LE
Sbjct: 944 PGISLHMSRLIKICMNEEPGKRPRFDMIIPILE 846
>32000
Length = 644
Score = 48.1 bits (113), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 39/148 (26%), Positives = 63/148 (42%), Gaps = 31/148 (20%)
Frame = -1
Query: 267 AGELKIADFGWS--VHAPSSRRTTLCGTLDYLPPEMIEG-RMHDEKVDLWSLGVLCYEFL 323
++KIADFG + P T TL Y PE++ G R + VD+WSLG + E +
Sbjct: 581 TAKMKIADFGLARVFGLPVRTYTHEVITLWYRAPEILLGCRFYSVPVDIWSLGCIFVEMM 402
Query: 324 VGKPPFEANTYQETYKRISRVEFT-----------FPDF-----------------VTEG 355
+ F ++ + RI R T PD+ +++
Sbjct: 401 TRRALFPGDSEIDQLYRIFRTLGTPDEKVWPGVSKLPDYKPTFPKWPLKNLETVVSLSKV 222
Query: 356 ARDLISRLLKHNPSQRPMLREVLEHPWI 383
DL+ R+L +NP++R R + HP+
Sbjct: 221 GLDLLKRMLTYNPNRRISARSAMRHPYF 138
>07291
Length = 833
Score = 47.8 bits (112), Expect = 8e-06, Method: Compositional matrix adjust.
Identities = 25/97 (25%), Positives = 50/97 (51%), Gaps = 6/97 (6%)
Frame = +1
Query: 239 ELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHA-PSSRRTT----LCGTL 293
++A+ ++Y +V+HR++ N ++ G L+++D+G + P S T +
Sbjct: 73 QIADGMAYLQEVKVVHRNLAARNCIVTEDGRLQLSDYGVTGSLFPQSYYTADDSPARDLV 252
Query: 294 DYLPPEMIEGRMHDEKVDLWSLGVLCYEFLV-GKPPF 329
++ PE I+ K D+W+ GV+ +E L G P+
Sbjct: 253 KWMAPETIDNFHFSSKSDVWAFGVVLWELLTRGITPY 363
>01106
Length = 878
Score = 46.6 bits (109), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 46/147 (31%), Positives = 70/147 (47%), Gaps = 15/147 (10%)
Frame = +3
Query: 133 FEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQ--LEKAGVEHQLRREVEIQSHLRH 190
+ + R LG G F V+L + K +ALKV+ AQ E A E +L + V +S +
Sbjct: 324 YHVIRKLGWGHFSTVWLCWDLTCKRFVALKVVKSAQHYTETALDEVKLLKCVR-ESDVAD 500
Query: 191 PNILRLYGYFHD-------ATRVYLILEYAPLGTVYRELQKLSKFDEQRTATY-----IT 238
P + D T V ++ E LG Y L+ + + + Q + I
Sbjct: 501 PARAKCVQLLDDFKISGVNGTHVAMVFEV--LG--YNLLKLIIRSNYQGIPIHNVKLIIR 668
Query: 239 ELANALSYCHSK-RVIHRDIKPENLLL 264
++ LSY H+K R+IH DIKPEN+L+
Sbjct: 669 QVLEGLSYMHAKCRIIHTDIKPENILI 749
>18481
Length = 437
Score = 44.7 bits (104), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 38/119 (31%), Positives = 57/119 (47%), Gaps = 7/119 (5%)
Frame = -1
Query: 167 AQLEKAGVEHQL-RREVEIQSHL-RHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQK 224
++E V+HQL E ++ + RHP + +Y Y + L++E LG EL
Sbjct: 395 VKIEAIDVKHQLLHYEAKVYEQIGRHPGLPTMYHYGTEKHFNALVME--LLGPSLEELFV 222
Query: 225 LSK--FDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLG---SAGELKIADFGWS 278
+ K F + +L + L + H K IHRD+KP+N L+G L I DFG S
Sbjct: 221 ICKRRFTLKTILMVSDQLLSRLEFIHQKCFIHRDLKPDNFLMGLGRHCHRLYIIDFGLS 45
>32957
Length = 645
Score = 44.7 bits (104), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 20/60 (33%), Positives = 32/60 (53%)
Frame = +3
Query: 275 FGWSVHAPSSRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTY 334
F V R T CGT +Y+ PE+ E + + ++VD W LG+L +E L + ++ Y
Sbjct: 3 FALCVEKSGGRTRTFCGTREYMAPEVHERKEYGKEVDWWGLGILLHELLAAQIKKHSSCY 182
>31489
Length = 329
Score = 43.9 bits (102), Expect = 1e-04, Method: Composition-based stats.
Identities = 23/88 (26%), Positives = 43/88 (48%), Gaps = 6/88 (6%)
Frame = +3
Query: 182 VEIQSHLRHPNI------LRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTAT 235
++I H +H NI L+ +HD ++++ + ++R + E+
Sbjct: 3 IKILKHFKHDNIISIREILKPKDSYHDFKDIHVVFDLME-SDLHRIIYSDQPLTEEHIRY 179
Query: 236 YITELANALSYCHSKRVIHRDIKPENLL 263
++ ++ L Y HS V+HRD+KP NLL
Sbjct: 180 FLYQILRGLKYIHSANVVHRDLKPSNLL 263
>16708
Length = 1397
Score = 43.9 bits (102), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 64/266 (24%), Positives = 100/266 (37%), Gaps = 33/266 (12%)
Frame = -1
Query: 139 LGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNIL-RLY 197
LGKG FG VY AR L KA L+ + + H EVE + L +++
Sbjct: 1379 LGKGVFGKVYEAR--------LLSTHEKAALKTSILCHHSLDEVEALGRIEGGFYLAQMF 1224
Query: 198 GY------FHDATRVYLILEYAPLGTVYRELQK----LSKFDEQRTATYITELANALSYC 247
G F + E PL VY + + + + AL +
Sbjct: 1223 GAWVTCLPFPKMNILLHFYEMGPLCNVYAHYKNKEMPIRWSNPAMVCCIAGQXVCALEHI 1044
Query: 248 HSKRVIHRDIKPENLLLGSAGELKIADFG----WSVH-APSSRRTTLCG---TLDYLPPE 299
H V+H D+K +N+L+ + G K+ D+G + V+ AP+ ++ C T PP
Sbjct: 1043 HELGVVHMDVKADNVLVDAHGNCKLTDYGIAQLYKVYPAPTETHSSGCTNKRTFYTRPPA 864
Query: 300 -MIEGRMHDEKVD------------LWSL-GVLCYEFLVGKPPFEANTYQETYKRISRVE 345
M E+ D LW+L G + V +PP + + R E
Sbjct: 863 TMTPSERFSEEGDGIGTDYFRLGQMLWTLTGAVLLHVWVSRPPKLPD-----WCRTPESE 699
Query: 346 FTFPDFVTEGARDLISRLLKHNPSQR 371
+ G D I +L +P+ R
Sbjct: 698 LS-------GMSDFIEKLCHGDPNMR 642
>17253
Length = 483
Score = 43.9 bits (102), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 27/112 (24%), Positives = 53/112 (47%), Gaps = 13/112 (11%)
Frame = -1
Query: 180 REVEIQSHL-RHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQK--------LSKFDE 230
RE+ I L RHPN++ G + +++E+ G + L+K L+
Sbjct: 402 RELSIMRKLPRHPNVVSFMGCCTMSDPALILMEFCCHGDLLSFLRKRRPDRTVFLTSTAN 223
Query: 231 QRTA----TYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS 278
TA ++ +A +++ + +++HRD+ N+L+ K++DFG S
Sbjct: 222 DLTARDFFSFALHVARGMAHVANNKIVHRDVAARNVLISERNVCKVSDFGLS 67
>20640
Length = 1492
Score = 43.5 bits (101), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 38/144 (26%), Positives = 65/144 (45%), Gaps = 5/144 (3%)
Frame = +1
Query: 253 IHRDIKPENLLLGSAGELKIADFGW--SVHAPSSRRTTLCGT--LDYLPPEMIEGRMHDE 308
+HRD+ N L+G +KI+DFG SVH+ R + + ++P E I
Sbjct: 10 VHRDLATRNCLVGHDLVVKISDFGLARSVHSVDYYRGSEHDAIPIRWMPLEAILYNKFST 189
Query: 309 KVDLWSLGVLCYE-FLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHN 367
+ D+WS GV+ +E F P+ T++E + FV EG ++L
Sbjct: 190 QSDVWSFGVVLWEIFAFALQPYYGLTHEEVVR-----------FVKEG------KVLACP 318
Query: 368 PSQRPMLREVLEHPWITANSSKPS 391
P + E+++ W +++PS
Sbjct: 319 ERTPPPMYELMKQCWHRRPATRPS 390
>07836
Length = 1478
Score = 42.7 bits (99), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 49/195 (25%), Positives = 85/195 (43%), Gaps = 31/195 (15%)
Frame = -1
Query: 159 LALKVLFKAQLEKAGVEHQLRREVEIQSH--LRHPNILRLYGY----FHDATRVYLILEY 212
+A+K+ F + E RE E+ LRH NIL T+++LI +Y
Sbjct: 1469 VAVKIFFTTE------EASWFRETELYQTVLLRHENILGFIAADIKGTGSWTQLFLITDY 1308
Query: 213 APLGTVYRELQKLSK-FDEQRTATYITELANALSYCHSK--------RVIHRDIKPENLL 263
G+++ L LS+ D L++ H + + HRDIK +N+L
Sbjct: 1307 HENGSLHDYL--LSRVLDSSEMLALAHSAICGLAHLHIEIFGTRGKPAIAHRDIKSKNIL 1134
Query: 264 LGSAGELKIADFGWSVH----------APSSRRTTLCGTLDYLPPEMIEGRMHD------ 307
+ G IAD G +V AP+ R+ GT Y+ PE++E ++
Sbjct: 1133 VKKNGTCCIADLGLAVRYISESNEVDVAPNPRQ----GTKRYMAPEVLEMLLNVKNFDAF 966
Query: 308 EKVDLWSLGVLCYEF 322
++ D+++ G++ +E
Sbjct: 965 KQADMYAFGLVMWEI 921
>20559
Length = 430
Score = 39.7 bits (91), Expect(2) = 3e-04, Method: Compositional matrix adjust.
Identities = 22/81 (27%), Positives = 45/81 (55%)
Frame = -2
Query: 130 LEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLR 189
++ +E +G+G +G V+ A+ +++ I+ALK + + + GV RE+ + L+
Sbjct: 378 MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRV-RLDDDDEGVPSSALREICLLKELK 202
Query: 190 HPNILRLYGYFHDATRVYLIL 210
H NI+RL+ H ++ L+
Sbjct: 201 HRNIVRLHDVLHSERKLTLVF 139
Score = 21.9 bits (45), Expect(2) = 3e-04, Method: Compositional matrix adjust.
Identities = 7/12 (58%), Positives = 9/12 (75%)
Frame = -1
Query: 244 LSYCHSKRVIHR 255
L +CHS V+HR
Sbjct: 37 LVFCHSNNVLHR 2
>17300
Length = 480
Score = 42.0 bits (97), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 29/98 (29%), Positives = 46/98 (46%), Gaps = 7/98 (7%)
Frame = +1
Query: 253 IHRDIKPENLLLGSAGELKIADFGWSVHAPSSRR----TTLCGTL--DYLPPEMIEGRMH 306
+HRD+ N+L+ K+ADFG S S TT G + + PE I R
Sbjct: 40 VHRDLAARNILVNEILVCKVADFGLSREIESDTTEGAYTTKGGKIPVRWTAPEAIAYRKF 219
Query: 307 DEKVDLWSLGVLCYEFL-VGKPPFEANTYQETYKRISR 343
D+WS GV+ +E + G+ P+ + Q+ K + +
Sbjct: 220 TSASDVWSFGVVMWEVMSYGERPYWNWSNQDVIKAVEK 333
>11404
Length = 563
Score = 40.8 bits (94), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 42/150 (28%), Positives = 71/150 (47%), Gaps = 12/150 (8%)
Frame = +1
Query: 127 QWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKV-------LFKAQLEKAGVEHQLR 179
+WA + +EI +GKG FG V A + +A+K+ L +AQ+E +E R
Sbjct: 130 KWA-DRYEIDSLIGKGSFGQVVKAYDHTDNEQVAIKIIKNKKPFLNQAQIEVKLLEMMNR 306
Query: 180 REVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKF---DEQRTATY 236
+ + + + I+RL +F R +L L + L +L + + F T +
Sbjct: 307 HDTDNKYY-----IVRLKRHF--MFRSHLCLVFELLSYNLYDLLRNTNFRGVSLNLTRKF 465
Query: 237 ITELANALSYCHS--KRVIHRDIKPENLLL 264
+L AL + + +IH D+KPEN+LL
Sbjct: 466 AQQLCTALLFLATPEMSIIHCDLKPENILL 555
>21210
Length = 518
Score = 40.4 bits (93), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 27/106 (25%), Positives = 49/106 (46%), Gaps = 13/106 (12%)
Frame = +3
Query: 291 GTLDYLPPEMIEGRM----HDEKVDLWSLGVLCYEFLVGKPPFE--ANTYQETYKRISRV 344
G Y+ PE I+ R +D + D+WSLG+ E G+ P+ + + + + + V
Sbjct: 6 GCRPYMAPERIDPRASSHGYDVRSDVWSLGITLMELATGRFPYRKWVSIFDQLQQVVRGV 185
Query: 345 EFTFP-------DFVTEGARDLISRLLKHNPSQRPMLREVLEHPWI 383
P DFV + +++ L + QRP ++L HP++
Sbjct: 186 APCLPHDGAFSHDFV-----NFVNKCLTKDEKQRPKYNKLLAHPFV 308
>21418
Length = 831
Score = 39.7 bits (91), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 20/56 (35%), Positives = 32/56 (57%), Gaps = 4/56 (7%)
Frame = +2
Query: 339 KRISRVEFTFPD----FVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKP 390
KRI ++ FPD V++ A+DLI +L +PS+R + +VL + WI + P
Sbjct: 8 KRIRSGQYDFPDPEWTNVSQAAKDLIKGMLNVDPSKRLCIEDVLRNKWIAQYDAVP 175
>20160
Length = 1277
Score = 38.5 bits (88), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 15/33 (45%), Positives = 24/33 (72%)
Frame = +2
Query: 354 EGARDLISRLLKHNPSQRPMLREVLEHPWITAN 386
E A DLI+R + +PS RP+L ++L+H W+T +
Sbjct: 332 EDAADLINRCIALDPSTRPVLADILKHKWMTKD 430
>00638
Length = 1595
Score = 38.1 bits (87), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 15/37 (40%), Positives = 21/37 (56%)
Frame = +2
Query: 223 QKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKP 259
Q F + Y+ EL AL +CHS ++HRD+KP
Sbjct: 392 QLYQTFTDYDIRFYLYELMKALDFCHSMGIMHRDVKP 502
>31789
Length = 676
Score = 36.6 bits (83), Expect = 0.018, Method: Compositional matrix adjust.
Identities = 27/103 (26%), Positives = 45/103 (43%), Gaps = 5/103 (4%)
Frame = +2
Query: 132 DFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHP 191
D EIGR G F VY + + +A L + K + + E E+ L+HP
Sbjct: 335 DVEIGR----GSFKTVYKGLDTELGVAVAWCELQDKKWNKT-ERQRFKEEAEMLKELQHP 499
Query: 192 NILRLYGYFHDATR-----VYLILEYAPLGTVYRELQKLSKFD 229
NI+R + Y+ + + L+ E GT+ L++ K +
Sbjct: 500 NIVRFFDYWEEHNHRNRKVIILVTELMTSGTLKTYLKRFKKIN 628
>36002
Length = 253
Score = 36.2 bits (82), Expect = 0.023, Method: Compositional matrix adjust.
Identities = 21/66 (31%), Positives = 31/66 (46%), Gaps = 5/66 (7%)
Frame = +1
Query: 324 VGKPPFEANTYQET-YKRISRVEFTFPDF----VTEGARDLISRLLKHNPSQRPMLREVL 378
V +P QE + RI + FP ++ A+DLI LL P +R +VL
Sbjct: 16 VAEPGEACQDCQELLFNRIQDGNYFFPSMEWSAISSSAKDLIRHLLVREPRKRYSAADVL 195
Query: 379 EHPWIT 384
+HPW+
Sbjct: 196 KHPWVC 213
>37063
Length = 455
Score = 35.4 bits (80), Expect = 0.043, Method: Compositional matrix adjust.
Identities = 23/77 (29%), Positives = 41/77 (53%), Gaps = 15/77 (19%)
Frame = -2
Query: 257 IKPENLLLGSAGE---LKIADF----GWSVHAPSSRRTTL---CGTLDYLPPEMIEGRM- 305
+KPEN+L E LKI DF G + ++ L G+ +Y+ PE+++ +
Sbjct: 454 LKPENILCEHLDEVVPLKICDFDLASGINCDGDGTKTPELLTPVGSAEYMAPEVVDAWVG 275
Query: 306 ----HDEKVDLWSLGVL 318
+D++ D+WSLG++
Sbjct: 274 ESFSYDKRCDMWSLGII 224
>20655
Length = 1181
Score = 34.7 bits (78), Expect = 0.068, Method: Compositional matrix adjust.
Identities = 17/56 (30%), Positives = 31/56 (55%), Gaps = 4/56 (7%)
Frame = +2
Query: 339 KRISRVEFTFP----DFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKP 390
KRI ++ FP V++ A+DLI +L +P +R +++V+ W+ N+ P
Sbjct: 8 KRIRNGQYEFPKPEWSRVSQDAKDLIRGMLCTDPDKRLNIKQVMASKWVADNTMVP 175
>00394
Length = 548
Score = 34.7 bits (78), Expect = 0.079, Method: Compositional matrix adjust.
Identities = 23/94 (24%), Positives = 43/94 (45%), Gaps = 5/94 (5%)
Frame = -2
Query: 137 RPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRL 196
+ +G+G F VY + + +A L + KA + + E E+ L+HPNI+R
Sbjct: 280 KEIGRGSFKTVYKGLDTELGVAVAWCELQDKKWNKAE-RQRFKEEAEMLKELQHPNIVRF 104
Query: 197 YGYFHDATR-----VYLILEYAPLGTVYRELQKL 225
+ Y+ + + L+ E GT+ L++
Sbjct: 103 FDYWEEHNHRNRKVIILVTELMTSGTLKTYLKRF 2
>18401
Length = 463
Score = 32.7 bits (73), Expect = 0.26, Method: Compositional matrix adjust.
Identities = 16/63 (25%), Positives = 29/63 (46%)
Frame = -3
Query: 287 TTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEF 346
+T+ T Y PE+I D+WS+G + +E G F+ + +E + R+
Sbjct: 458 STIVSTRHYRAPEVILELGWSHPCDVWSVGCIMFELYTGYTLFQTHDNKEHLAMMERILG 279
Query: 347 TFP 349
+ P
Sbjct: 278 SLP 270
>20773
Length = 391
Score = 32.0 bits (71), Expect = 0.48, Method: Compositional matrix adjust.
Identities = 17/54 (31%), Positives = 28/54 (51%)
Frame = -1
Query: 330 EANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWI 383
+ + ++R SR F VT+ +L+ RLL ++PSQR L HP++
Sbjct: 388 SGSCWSGLHRRRSRPVFPHTTVVTQHFYNLVQRLLTYDPSQRLTPDLALSHPFV 227
>21800
Length = 855
Score = 32.0 bits (71), Expect = 0.49, Method: Compositional matrix adjust.
Identities = 17/46 (36%), Positives = 26/46 (56%), Gaps = 5/46 (10%)
Frame = +2
Query: 237 ITELANALSYCHSK-RVIHRDIKPENLLLGSAG----ELKIADFGW 277
I ++ L+Y H+K +IH DIKPEN+L+ +L + F W
Sbjct: 650 IRQVLEGLNYLHAKCNIIHTDIKPENILICVDDNYIRKLAVDAFEW 787
>36481
Length = 806
Score = 32.0 bits (71), Expect = 0.51, Method: Compositional matrix adjust.
Identities = 32/141 (22%), Positives = 65/141 (46%), Gaps = 8/141 (5%)
Frame = +2
Query: 132 DFEIGRPLGKGKFGNVYLAREKQSKFILALKVL--FKAQLEKAGVE-HQLRREVEIQSHL 188
D ++ G+G FG V ++ +ALK++ E A +E + L + E H
Sbjct: 365 DMKLCPHWGEGTFGKVVQCKDLLKGDDIALKIIKNVDKYREAAKLEINVLEKLREKDPHA 544
Query: 189 RHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKF-----DEQRTATYITELANA 243
+H + L + + ++ + + LG + K + + ++ R +Y +L A
Sbjct: 545 KHMCVQMLDWFDYHG---HVCISFHMLGLSVFDFLKDNSYGAYPIEQVRHISY--QLCYA 709
Query: 244 LSYCHSKRVIHRDIKPENLLL 264
+++ H ++ H D+KPEN+L
Sbjct: 710 VNFLHENQLTHTDLKPENILF 772
>19872
Length = 446
Score = 31.6 bits (70), Expect = 0.53, Method: Compositional matrix adjust.
Identities = 14/41 (34%), Positives = 25/41 (60%), Gaps = 4/41 (9%)
Frame = +3
Query: 349 PDFVTEGA----RDLISRLLKHNPSQRPMLREVLEHPWITA 385
PDF + L+ ++L H+P+QRP R++L+ P++ A
Sbjct: 99 PDFTKDADLHNQSALLRQMLSHDPTQRPSSRDLLQSPYLPA 221
>17932
Length = 597
Score = 28.1 bits (61), Expect(2) = 0.76, Method: Compositional matrix adjust.
Identities = 14/31 (45%), Positives = 16/31 (51%), Gaps = 2/31 (6%)
Frame = -2
Query: 313 WSLGVLCYEFLVGKPPF--EANTYQETYKRI 341
WSLGV YE L G PF + + TY I
Sbjct: 593 WSLGVCAYEMLFGCTPFTDDDGSMVATYNNI 501
Score = 21.6 bits (44), Expect(2) = 0.76, Method: Compositional matrix adjust.
Identities = 14/32 (43%), Positives = 20/32 (62%)
Frame = -3
Query: 352 VTEGARDLISRLLKHNPSQRPMLREVLEHPWI 383
V++ ARDLIS+LL S R E+ +HP+
Sbjct: 460 VSKEARDLISQLLSDGKS-RLGWPELQQHPFF 368
>16350
Length = 1108
Score = 29.6 bits (65), Expect = 2.1, Method: Compositional matrix adjust.
Identities = 12/39 (30%), Positives = 23/39 (58%), Gaps = 1/39 (2%)
Frame = +3
Query: 358 DLISRLLKHNPSQRPMLREVLEHPWITANS-SKPSNCQN 395
D ++ +L+ +P QR + L+HPW+ ++ +PS Q
Sbjct: 762 DFLAPMLEFDPEQRATAAQSLQHPWLKLDA*PEPSGSQQ 878
>20513
Length = 405
Score = 29.3 bits (64), Expect = 2.9, Method: Compositional matrix adjust.
Identities = 12/39 (30%), Positives = 23/39 (58%), Gaps = 1/39 (2%)
Frame = -1
Query: 358 DLISRLLKHNPSQRPMLREVLEHPWITANS-SKPSNCQN 395
D ++ +L+ +P QR + L+HPW+ ++ +PS Q
Sbjct: 282 DFLAPMLEFDPEQRATAAQSLQHPWLKLDA*PEPSGSQQ 166
>17644
Length = 463
Score = 27.7 bits (60), Expect = 8.1, Method: Compositional matrix adjust.
Identities = 13/32 (40%), Positives = 19/32 (59%)
Frame = +3
Query: 352 VTEGARDLISRLLKHNPSQRPMLREVLEHPWI 383
VT+ BL+ RLL ++PSQR L HP++
Sbjct: 69 VTQHFYBLVQRLLTYDPSQRLTPDLALSHPFV 164
>18929
Length = 440
Score = 27.7 bits (60), Expect = 9.8, Method: Compositional matrix adjust.
Identities = 11/38 (28%), Positives = 22/38 (57%)
Frame = +1
Query: 348 FPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITA 385
F + ++ + +I R++ +P QRP ++L HP + A
Sbjct: 34 FINTISVELQQVIRRMMSPDPRQRPTANQLLAHPTLAA 147
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000379245 | hsapiens_gene_ensembl |
Serine/threonine-protein kinase 6 (EC 2.7.11.1) (Aurora kinase A)
(Aurora-A) (Serine/threonine kinase 15) (Aurora/IPL1-related kinase 1)
(Aurora-related kinase 1) (hARK1) (Breast-tumor-amplified kinase).
[Source:Uniprot/SWISSPROT;Acc:O14965]
(403 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
21433 184 3e-69
15910 120 8e-28
03240 119 2e-27
01060 117 6e-27
00300 114 8e-26
30755 110 1e-24
18484 110 1e-24
18921 107 7e-24
12721 105 4e-23
14420 101 5e-22
01707 99 3e-21
14126 98 5e-21
09606 97 8e-21
06405 97 9e-21
09007 94 8e-20
13592 93 2e-19
13212 92 3e-19
01392 91 1e-18
01756 87 1e-17
13066 87 1e-17
11780 80 2e-17
04591 86 2e-17
01718 86 3e-17
17975 85 4e-17
31885 84 7e-17
27546 83 2e-16
00486 82 3e-16
21079 82 6e-16
00392 80 1e-15
01966 79 3e-15
19761 76 2e-14
19094 70 6e-14
26560 75 7e-14
29581 72 4e-13
20152 69 3e-12
27405 68 7e-12
26711 66 3e-11
19301 65 5e-11
38560 65 6e-11
14477 64 1e-10
04852 64 1e-10
06358 64 1e-10
04138 64 2e-10
21808 63 2e-10
00715 62 5e-10
14116 61 6e-10
28157 61 8e-10
12672 61 9e-10
07940 61 1e-09
03508 61 1e-09
26009 41 3e-09
12786 59 3e-09
18663 58 7e-09
28638 56 3e-08
02638 53 2e-07
11185 52 3e-07
25019 52 4e-07
29590 39 1e-06
27274 50 2e-06
31120 49 4e-06
37602 49 4e-06
07833 48 6e-06
32000 48 6e-06
07291 48 8e-06
01106 47 2e-05
18481 45 6e-05
32957 45 6e-05
31489 44 1e-04
16708 44 1e-04
17253 44 1e-04
20640 44 1e-04
07836 43 3e-04
20559 40 3e-04
17300 42 4e-04
11404 41 0.001
21210 40 0.001
21418 40 0.002
20160 39 0.006
00638 38 0.006
31789 37 0.018
36002 36 0.023
37063 35 0.043
20655 35 0.068
00394 35 0.079
18401 33 0.26
20773 32 0.48
21800 32 0.49
36481 32 0.51
19872 32 0.53
17932 28 0.76
16350 30 2.1
20513 29 2.9
17644 28 8.1
18929 28 9.8
>21433
Length = 590
Score = 184 bits (467), Expect(2) = 3e-69, Method: Compositional matrix adjust.
Identities = 93/136 (68%), Positives = 107/136 (78%)
Frame = +2
Query: 231 QRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLC 290
+RTA YI +L++AL YCH ++VIHRDIKPENLLLG G+LKIADFGWSVHAPSSRRTT+C
Sbjct: 167 KRTACYIYQLSSALEYCHYRKVIHRDIKPENLLLGLKGDLKIADFGWSVHAPSSRRTTMC 346
Query: 291 GTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPD 350
GTLDYLPPEM+EG+ HDE VDLWSLGVLCYEFLVG PP + + R P
Sbjct: 347 GTLDYLPPEMVEGKTHDENVDLWSLGVLCYEFLVGTPPLRPSPTRPPTPASPRWTSGSPS 526
Query: 351 FVTEGARDLISRLLKH 366
VT GARDLIS+LL+H
Sbjct: 527 IVTPGARDLISKLLRH 574
Score = 95.9 bits (237), Expect(2) = 3e-69, Method: Compositional matrix adjust.
Identities = 44/64 (68%), Positives = 54/64 (84%), Gaps = 1/64 (1%)
Frame = +3
Query: 176 HQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDE-QRTA 234
HQLRRE+EIQSHLRH NILR++GYFHD TRVYLILE+AP G +Y+ELQ+ KFDE ++ A
Sbjct: 3 HQLRREIEIQSHLRHDNILRMFGYFHDKTRVYLILEFAPKGELYKELQRCHKFDENEQHA 182
Query: 235 TYIT 238
Y +
Sbjct: 183 IYTS 194
>15910
Length = 1361
Score = 120 bits (302), Expect = 8e-28, Method: Compositional matrix adjust.
Identities = 61/177 (34%), Positives = 104/177 (58%), Gaps = 8/177 (4%)
Frame = +2
Query: 226 SKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLL---LGSAGELKIADFGWS-VHA 281
++ E+ A I+++ + + Y H+ V+HRD+KPENLL + +LK+ADFG S +
Sbjct: 449 GQYTEKDAARAISDILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLADFGLSRIIE 628
Query: 282 PSSRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRI 341
P + +T+CGT Y PE+++G + VD+WS+GV+ Y L G PF A E Y++I
Sbjct: 629 PEVQMSTVCGTPGYCAPEVLKGDKYTPSVDMWSVGVIAYILLCGYEPFFAENEFEMYRKI 808
Query: 342 SRVEFTFPD----FVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQ 394
+ E+ F + ++E A+D++ +LL +P +R E L PW+ ++K +N +
Sbjct: 809 IKGEYKFDEEYWSEISENAKDVVRKLLVIDPKKRLTATEALRLPWVKGVATKTTNME 979
>03240
Length = 1683
Score = 119 bits (298), Expect = 2e-27, Method: Compositional matrix adjust.
Identities = 86/283 (30%), Positives = 133/283 (46%), Gaps = 52/283 (18%)
Frame = -3
Query: 133 FEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPN 192
FE + LG G FG V L R+ + + A+K L K+ + K ++ E +I + +
Sbjct: 1285 FEKIKTLGVGAFGEVSLCRKNDTGMLYAMKTLRKSDVLKRNQVAHVKAERDILAEADNEW 1106
Query: 193 ILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRV 252
+++LY F D +Y +++Y P G + L ++ DE Y+ EL A+ H
Sbjct: 1105 VVKLYYSFQDHNYLYFVMDYVPGGDLMGLLIRMEILDEPLARFYVAELVQAIESVHRMGF 926
Query: 253 IHRDIKPENLLLGSAGELKIADFG------WS----------VHA--------------- 281
IHRDIKP+N+L+ G +K+ DFG W+ HA
Sbjct: 925 IHRDIKPDNILIDRNGHIKLTDFGLCTGFRWTHNSKYYQRDGTHARQDSMEVKCQLDEQC 746
Query: 282 ------PSSRRT---------TLCGTLDYLPPEMIEGRM--HDEKVDLWSLGVLCYEFLV 324
P RR +L GT +Y+ PE++ R+ + D WS+GV+ +E LV
Sbjct: 745 QCEILKPLERRRKREQRCLAHSLVGTPNYIAPEVL-SRLGGYTSVCDWWSVGVILFEMLV 569
Query: 325 GKPPFEANTYQET-YKRIS---RVEFTFPDFVTEGARDLISRL 363
G PPF ANT ET YK I+ ++ +++ A+DLI RL
Sbjct: 568 GHPPFYANTPAETQYKVINWKDMLKIPRESNLSQPAKDLILRL 440
>01060
Length = 1800
Score = 117 bits (294), Expect = 6e-27, Method: Compositional matrix adjust.
Identities = 83/305 (27%), Positives = 145/305 (47%), Gaps = 36/305 (11%)
Frame = +1
Query: 129 ALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHL 188
AL D + +G+G +G VY R + + LA+K + + + + GV RE+ + L
Sbjct: 67 ALSDLTDFQKIGEGTYGVVYKCRHRATGRKLAMKKI-RLRGSEDGVPSSAIREIAMLREL 243
Query: 189 RHPNILRLYGYFHDATRVYLILEY--APLGTVYRELQKLSKFDEQRTATYITELANALSY 246
RH NI+ L + R++L+ E+ L + + D + +Y+ ++ + +
Sbjct: 244 RHTNIVCLEDVIMEDERLFLVFEFLSMDLKMYIDKFPEGVVLDRRLVKSYVFQIVTGIXF 423
Query: 247 CHSKRVIHRDIKPENLLLGSAGELKIADFGW--SVHAPSSRRTTLCGTLDYLPPEMIEG- 303
CH +R++HRD+KP+NLL+ G +KIADFG + P T TL Y PE++ G
Sbjct: 424 CHQRRIVHRDLKPQNLLINHTGAIKIADFGMARTFALPVRAYTHEVVTLWYRAPEILMGA 603
Query: 304 RMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRV-----EFTFPDF------- 351
+ VD+WS+G + + L+ P F+ ++ + +I R+ E T+P+F
Sbjct: 604 SKYSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKLPAFN 783
Query: 352 -----------------VTEGARDLISRLLKHNPSQRPMLREVLEHPWI--TANSSKPSN 392
+ DLI R LK +P+QR +++L+H + S KP +
Sbjct: 784 GMFPLWKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYFLNVDTSVKPVD 963
Query: 393 CQNKE 397
+ E
Sbjct: 964 VPSPE 978
>00300
Length = 2318
Score = 114 bits (285), Expect = 8e-26, Method: Compositional matrix adjust.
Identities = 74/257 (28%), Positives = 125/257 (48%), Gaps = 10/257 (3%)
Frame = -1
Query: 136 GRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILR 195
G +G+G+FG VY A + ++ALK + K Q ++ E++I ++H N+++
Sbjct: 1643 GNKIGEGQFGKVYTAVNMSTGELMALKEM-KFQPNDLQQLREMCDEIKIFEGIQHENLVK 1467
Query: 196 LYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHR 255
YG + + +EY GT+ E K+ E Y E+ A+++ H ++HR
Sbjct: 1466 YYGVEVHKDEMLMFMEYCDTGTI-EEAAKMG-LPEYLIRRYTREIVLAVNHLHENSIVHR 1293
Query: 256 DIKPENLLLGSAGELKIADFGWSVHAPSSRRT-----TLCGTLDYLPPEMI---EGRMHD 307
DIK N+ L S G +K+ DFG SV S L GT Y+ PE+ + +
Sbjct: 1292 DIKGANIFLTSNGHVKLGDFGCSVKLKSHTTMPGEFHNLVGTTAYMAPEVFTQNDQGGYG 1113
Query: 308 EKVDLWSLGVLCYEFLVGKPPFE--ANTYQETYKRISRVEFTFPDFVTEGARDLISRLLK 365
D+WSLG + E GK P+ N YQ YK + PD ++ + + ++
Sbjct: 1112 RAADIWSLGCVVIEMATGKRPWHDLDNNYQIMYKVGIGHKPAVPDSLSVEGKHFLDLIMC 933
Query: 366 HNPSQRPMLREVLEHPW 382
H+P+QR + ++L+H +
Sbjct: 932 HDPAQRALASQLLDHTF 882
>30755
Length = 1137
Score = 110 bits (275), Expect = 1e-24, Method: Compositional matrix adjust.
Identities = 60/165 (36%), Positives = 91/165 (55%), Gaps = 7/165 (4%)
Frame = +2
Query: 228 FDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRT 287
F E+RT Y E+ +AL Y HS+ +I+RD+K ENLLL G +K+ADFG + RT
Sbjct: 23 FTEERTRFYGAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCKEDITYGRT 202
Query: 288 T--LCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVE 345
T CGT +YL PE+++ + VD W GV+ YE + G+ PF + + I +
Sbjct: 203 TKTFCGTPEYLAPEVLDDNDYGRAVDWWGTGVVMYEMICGRLPFYNRDHDVLFTLILVED 382
Query: 346 FTFPDFVTEGARDLISRLLKHNPSQR-----PMLREVLEHPWITA 385
FP +T+ A+ L+S LL +P R ++E+ HP+ +
Sbjct: 383 VKFPRNITDEAKSLLSGLLAKDPRNRLGGGQDDVKEIQAHPFFAS 517
>18484
Length = 635
Score = 110 bits (275), Expect = 1e-24, Method: Compositional matrix adjust.
Identities = 57/156 (36%), Positives = 89/156 (57%), Gaps = 2/156 (1%)
Frame = +1
Query: 218 VYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGW 277
+YR +Q+ KF E A Y E+A L + H + +I+RD+K +N++L S G +KIADFG
Sbjct: 7 MYR-IQQEGKFKEPVAAFYAAEIAVGLFFLHDQGIIYRDLKLDNVMLDSEGHIKIADFGM 183
Query: 278 SVHAPSSRRTT--LCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQ 335
+ TT CGT DY+ PE++ + + + VD W+ GVL +E L G+PPF+
Sbjct: 184 CKEGMTGDATTRTFCGTPDYIAPEIVLYQPYSKSVDWWAYGVLLFEMLAGQPPFDGEDED 363
Query: 336 ETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQR 371
E + I+ ++P ++ A L LL NP++R
Sbjct: 364 ELFSSITDHNVSYPKAMSREAVSLCKGLLMKNPTKR 471
>18921
Length = 697
Score = 107 bits (268), Expect = 7e-24, Method: Compositional matrix adjust.
Identities = 64/199 (32%), Positives = 109/199 (54%), Gaps = 3/199 (1%)
Frame = +2
Query: 133 FEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPN 192
F+I LG+G +G+V+ + K++ +LA+K Q+ ++ +E+ I
Sbjct: 35 FDILGKLGEGSYGSVFKSLHKETGQVLAIK-----QVPVDTDLQEIIKEISIMQQCDSKY 199
Query: 193 ILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSK-FDEQRTATYITELANALSYCHSKR 251
I++ YG + T +++++EY G+V ++ +K E+ AT + L Y HS+R
Sbjct: 200 IVKYYGSYFKNTDLWIVMEYCGAGSVSDIMRLRNKTLVEREIATILYYTLKGLXYLHSRR 379
Query: 252 VIHRDIKPENLLLGSAGELKIADFGWS--VHAPSSRRTTLCGTLDYLPPEMIEGRMHDEK 309
IHRDIK N+LL + G K+ADFG + + ++R T+ GT ++ PE+I+ +D
Sbjct: 380 KIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTPYWMAPEVIQEIGYDCV 559
Query: 310 VDLWSLGVLCYEFLVGKPP 328
D+WSLG+ E GKPP
Sbjct: 560 ADIWSLGITALEMAEGKPP 616
>12721
Length = 821
Score = 105 bits (261), Expect = 4e-23, Method: Compositional matrix adjust.
Identities = 69/247 (27%), Positives = 123/247 (49%), Gaps = 5/247 (2%)
Frame = +1
Query: 130 LEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLR 189
L+DF +G+G G V +A + + +A+K K L K L EV +
Sbjct: 94 LDDF---MKIGEGSTGIVCIATSRDGR-QMAVK---KMDLRKQQRRELLFNEVVVMRDYH 252
Query: 190 HPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHS 249
HPNI+ +Y + +++++E+ G ++ ++ DE + AT AL++ H+
Sbjct: 253 HPNIVEMYNSYLVNDELWVVMEFME-GGALTDIVTNNRMDEVQIATVCRACLKALAFLHA 429
Query: 250 KRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSS--RRTTLCGTLDYLPPEMIEGRMHD 307
VIHRDIK +++LL G++K+ DFG+ +R +L GT ++ PE+I +
Sbjct: 430 NGVIHRDIKSDSILLSHDGKVKLXDFGFCAQVTQDLQKRKSLVGTPYWMAPEVISRLPYG 609
Query: 308 EKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRV---EFTFPDFVTEGARDLISRLL 364
+VD+WSLG++ E + +PPF + +RI + + ++ + I R+L
Sbjct: 610 PEVDIWSLGIMVMEMIDAEPPFFNEPPLQAMRRIRDMPPPKLRNTHKISPRLQGFIDRML 789
Query: 365 KHNPSQR 371
+P QR
Sbjct: 790 VRDPHQR 810
>14420
Length = 528
Score = 101 bits (252), Expect = 5e-22, Method: Compositional matrix adjust.
Identities = 48/151 (31%), Positives = 87/151 (57%), Gaps = 2/151 (1%)
Frame = +2
Query: 181 EVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITEL 240
E+ + ++PNI+ + +++++E+ G++ + + + DE + A E
Sbjct: 50 EILVMRENQNPNIVNYLDSYLVGEELWVVMEFLAGGSLTDVVTE-TCMDEGQIAAVCREC 226
Query: 241 ANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAP--SSRRTTLCGTLDYLPP 298
AL + H +VIHRDIK +N+LLG G +K+ DFG+ S+R+T+ GT ++ P
Sbjct: 227 LQALEFLHENQVIHRDIKSDNILLGMDGSVKLTDFGFCAQLSPEQSKRSTMVGTPYWMAP 406
Query: 299 EMIEGRMHDEKVDLWSLGVLCYEFLVGKPPF 329
E++ + + VD+WSLGV+C E + G+PP+
Sbjct: 407 EVVTRKQYGPTVDIWSLGVMCIEMIEGEPPY 499
>01707
Length = 757
Score = 99.0 bits (245), Expect = 3e-21, Method: Compositional matrix adjust.
Identities = 58/201 (28%), Positives = 108/201 (53%), Gaps = 4/201 (1%)
Frame = +1
Query: 130 LEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLR 189
+E +E +G+G +G V+ R K++ ++A+K +++ + ++ RE+ + L+
Sbjct: 61 MEKYEKIGKIGEGSYGVVFKCRNKETSQLVAIKKFVESE-DDPLIKKIAMREIRMLKQLK 237
Query: 190 HPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSK-FDEQRTATYITELANALSYCH 248
HPN++RL F R++L+ +Y T+ EL + + E I + A+++CH
Sbjct: 238 HPNLVRLIEVFRRKKRLHLVFDYVD-HTLLNELDRYPRGLPEPMVKRIIYQTLLAVNFCH 414
Query: 249 SKRVIHRDIKPENLLLGSAGELKIADFGWS--VHAPSSRRTTLCGTLDYLPPEMIEGRM- 305
IHRD+KPEN+L+ G++K+ DFG++ + P T T Y PE++ G
Sbjct: 415 QYNTIHRDVKPENILITRQGQVKLCDFGFARILTGPGDEYTDYVATRWYRAPELLVGDTQ 594
Query: 306 HDEKVDLWSLGVLCYEFLVGK 326
+ VD+W++G + E L G+
Sbjct: 595 YGPPVDVWAIGCVFAELLTGQ 657
>14126
Length = 1265
Score = 98.2 bits (243), Expect = 5e-21, Method: Compositional matrix adjust.
Identities = 86/332 (25%), Positives = 146/332 (43%), Gaps = 46/332 (13%)
Frame = +3
Query: 116 SKQKNEESKKRQWALEDFEIGRPLGKGKFGNVYLARE--KQSKFILALKVLFKAQLEKAG 173
S+ + S++R + +E +G G +G VY AR+ Q +F+ ++ E G
Sbjct: 144 SESAAKMSRRRDSTEQKYEEVAVIGNGAYGTVYKARDLRNQGEFVAMKRIRLNNTEE--G 317
Query: 174 VEHQLRREVEIQSHLR---HPNILRLYGYFHDAT-----RVYLILEYA--PLGTVYRELQ 223
+ RE+ + L HPN++RL H+ R+ L+ EY L T Y
Sbjct: 318 MPMMAIREISMLKQLEQYEHPNVVRLLDVSHNTITDREIRLNLVFEYIEHDLAT-YLAKC 494
Query: 224 KLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS-VHAP 282
R + +L N + + HS R++HRD+KP+NLL+ G LK+ADFG + +++
Sbjct: 495 PSPGLGPDRIKDLMLQLLNGVDFLHSNRIVHRDLKPQNLLISKDGRLKLADFGLARIYSF 674
Query: 283 SSRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRIS 342
TT+ TL Y PE++ + VD+WS G + E + F+ ++ + K+I
Sbjct: 675 HMALTTVVVTLWYRSPEVLMQAEYGTSVDIWSCGCIFAELFTRRALFKGSSEFDQLKKIF 854
Query: 343 RV-----EFTFPDFVTEG----------------------ARDLISRLLKHNPSQRPMLR 375
V +P+ V+ A+DL+ ++L +R R
Sbjct: 855 EVIGLPPAGDWPEGVSVHRNSFRPTPPVPLQTLVPEMDPQAKDLMEKMLVFKSGRRISSR 1034
Query: 376 EVLEHPWITAN------SSKPSNCQNKESASK 401
E L HP++ + SS S +N S +
Sbjct: 1035ESLLHPYLRDDLDSIRTSSSLSTSENDSSDGR 1130
>09606
Length = 1300
Score = 97.4 bits (241), Expect = 8e-21, Method: Compositional matrix adjust.
Identities = 66/285 (23%), Positives = 126/285 (44%), Gaps = 34/285 (11%)
Frame = -3
Query: 130 LEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLR 189
+E+F + LGKG+ +Y R K + +A+ + K + ++ V + +
Sbjct: 1118 MENFVLYEELGKGEHSIIYKGRRKGTINFVAIHCIEKCK------RPEVTNTVRMTHDIS 957
Query: 190 HPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHS 249
HPN+++ + ++ + ++L++E G++ L + E + L L Y HS
Sbjct: 956 HPNVVQFHEWYETSNHLWLVVELCTGGSLADILAQDHHLPETSIRDFGIHLVTGLHYIHS 777
Query: 250 KRVIHRDIKPENLLLGSAGELKIADFG----------------------WSVHAPSS--R 285
++ D++P +LL ++G LK ADFG W++ + +
Sbjct: 776 LGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQWNIQSAEEMMK 597
Query: 286 RTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVE 345
+ G+ Y+ PE+ +G DLW+LG + YE G PPF TY T ++ E
Sbjct: 596 QVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSGHPPFLGETYDITKDKVLNKE 417
Query: 346 FTFPDFVTEGAR----------DLISRLLKHNPSQRPMLREVLEH 380
F P +G+R +L+ LL+ + ++R +++H
Sbjct: 416 FPLPK--VKGSRLSAKPSPEFLNLLESLLQKDSTRRLSWASLVKH 288
>06405
Length = 1965
Score = 97.4 bits (241), Expect = 9e-21, Method: Compositional matrix adjust.
Identities = 68/260 (26%), Positives = 118/260 (45%), Gaps = 9/260 (3%)
Frame = +1
Query: 127 QWALEDFEIGRP--LGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEI 184
+W +E EI LG G++G+VY A K+ I+A+K L E + E I
Sbjct: 241 RWEIERTEIAMKHRLGGGQYGDVYEAMWKRYNKIVAVKTL----KEDTMALNDFLEEAAI 408
Query: 185 QSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTA-TYI-TELAN 242
++HPN+++L G Y++ E+ P G + L+ ++ + TA Y+ T++A+
Sbjct: 409 MKEMKHPNLVQLLGVCTREPPFYIVTEFMPHGNLLDYLRSSTREENGPTALMYMATQIAS 588
Query: 243 ALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGT---LDYLPPE 299
++Y +K IHRD+ N L+ + +K+ADFG + T G + + PE
Sbjct: 589 GMAYLETKNFIHRDLAARNCLVADSNMVKVADFGLARLMKDDTYTAHIGAKFPIKWTAPE 768
Query: 300 MIEGRMHDEKVDLWSLGVLCYEFLV-GKPPFEANTYQETYKRISR-VEFTFPDFVTEGAR 357
+ + D+W+ GVL +E G P+ E Y + R P
Sbjct: 769 GLAFNRFSTRSDIWAFGVLLWELATYGMSPYPGVELTEVYHLLERGYRMERPPGTPADVY 948
Query: 358 DLISRLLKHNPSQRPMLREV 377
L+ + + +P RP +E+
Sbjct: 949 ILMLKCWQWDPKDRPTFKEI 1008
>09007
Length = 1440
Score = 94.4 bits (233), Expect = 8e-20, Method: Compositional matrix adjust.
Identities = 71/264 (26%), Positives = 122/264 (46%), Gaps = 20/264 (7%)
Frame = -1
Query: 135 IGRPLGKGKFGNVYLA---REKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHP 191
+ + LG+G FG V A E K +A+K L K ++ K G E +E I L H
Sbjct: 867 LSKSLGQGHFGTVRQAIWTAESGEKVQVAVKCLSKDKIHKDGQE--FLKETAIMQMLDHE 694
Query: 192 NILRLYGYFHD-ATRVYLILEYAPLGTVYRELQKLS---KFDEQRTATYITELANALSYC 247
NI+R+YG D + L+ E AP+ ++ ++++S F R + ++ + +SY
Sbjct: 693 NIVRVYGVVMDNGADIMLVTELAPMRSLLECVKEVSARVDFSVPRLCDFSQQVCDGMSYL 514
Query: 248 HSKRVIHRDIKPENLLLGSAGELKIADFGWSV-------HAPSSRRTTLCGTLDYLPPEM 300
SKR++HRD+ N+LL S ++KI+D G S + S + L + + PE
Sbjct: 513 ESKRLVHRDLAARNILLFSKSKVKISDVGVSGALGAGKEYYQSQQTIHLQNAVAWCAPES 334
Query: 301 IEGRMHDEKVDLWSLGVLCYEFLV-GKPPFEANTYQETYKRIS-----RVEFTFPDFVTE 354
D+W+ GVL +EF G P+ Q+ + + R+E PD +
Sbjct: 333 FRNLCFSSASDVWAFGVLLWEFFTHGFQPWAGLNGQQIMEAVDAPQSQRLE--QPDLCPK 160
Query: 355 GARDLISRLLKHNPSQRPMLREVL 378
++ + + P +RP ++
Sbjct: 159 EYYAVMLKCWEQEPQRRPTFSQLF 88
>13592
Length = 980
Score = 93.2 bits (230), Expect = 2e-19, Method: Compositional matrix adjust.
Identities = 68/270 (25%), Positives = 128/270 (47%), Gaps = 14/270 (5%)
Frame = +2
Query: 139 LGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYG 198
+G+G+FG VY A + ++A+K + E +++ + E++I ++H N++R YG
Sbjct: 8 IGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETRALKN-VAEELKILEGIKHKNLVRYYG 184
Query: 199 YFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIK 258
+ + +E GT+ ++ E + + +L + ++ H ++HRDIK
Sbjct: 185 IEVHREELLIFMELCSEGTLESLVELTGGLPEALSRRFTAQLLSGVAELHKHGIVHRDIK 364
Query: 259 PENL-LLGSAGELKIADFGWSVHAPSSRRTTL-------CGTLDYLPPEMI---EGRMHD 307
N+ L+ + LK+ DFG +V + TT+ GT Y+ PE+ H
Sbjct: 365 TANIFLVDGSNSLKLGDFGSAVKIQA--HTTVPGELQGYVGTQAYMAPEVFTKTNSDGHG 538
Query: 308 EKVDLWSLGVLCYEFLVGKPP---FEANTYQETYKRISRVEFTFPDFVTEGARDLISRLL 364
D+WS+G + E GK P F++N +Q +K + P+ +++ D I L
Sbjct: 539 RLADIWSVGCVVVEMASGKRPWAQFDSN-FQIMFKVGMGEKPQAPESLSQEGHDFIDHCL 715
Query: 365 KHNPSQRPMLREVLEHPWITANSSKPSNCQ 394
+H+P QR E+LE + + + N +
Sbjct: 716 QHDPKQRLSAIELLEQNFCKSGRDEECNSE 805
>13212
Length = 1067
Score = 92.4 bits (228), Expect = 3e-19, Method: Compositional matrix adjust.
Identities = 60/188 (31%), Positives = 96/188 (51%), Gaps = 10/188 (5%)
Frame = -1
Query: 206 VYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLG 265
V+ +L + L ++ +L+K E + E+ AL + H VIHRDIK N+LL
Sbjct: 1049 VFRVLWWGALDSIMVDLEK--PMTEAQICYVCHEMCMALDFLHRHHVIHRDIKAGNVLLT 876
Query: 266 SAGELKIADFGWSVHAPSS--RRTTLCGTLDYLPPEMI-----EGRMHDEKVDLWSLGVL 318
GE+K+ADFG S + +R T GT ++ PE++ + +D K D+WSLGV
Sbjct: 875 IDGEVKLADFGVSAKNTQTQQKRDTFIGTPYWMAPEVVLCETLKDTPYDFKADIWSLGVT 696
Query: 319 CYEFLVGKPPFEANTYQETYKRISRVE---FTFPDFVTEGARDLISRLLKHNPSQRPMLR 375
EF +PP + +I + + P T+ +D I++ L +P+ RP
Sbjct: 695 LIEFAQIEPPNKEMHPMRVLIKIHKSDPPTLEKPKKWTKLFKDFIAKCLVKDPNLRPTAA 516
Query: 376 EVLEHPWI 383
E+LEHP++
Sbjct: 515 ELLEHPFM 492
>01392
Length = 1806
Score = 90.5 bits (223), Expect = 1e-18, Method: Compositional matrix adjust.
Identities = 57/189 (30%), Positives = 90/189 (47%), Gaps = 34/189 (17%)
Frame = -1
Query: 230 EQRTATYITELANALSYCHSKRVIHRDIKPENLL---LGSAGELKIADF----GWSVHAP 282
E+ + + +A AL + HSK + HRD+KPEN+L L +KI DF G S
Sbjct: 1794 EREASLVVRHIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGISCDGD 1615
Query: 283 SSRRTTL---CGTLDYLPPEMIEGRM-----HDEKVDLWSLGVLCYEFLVGKPPFEANTY 334
++ L G+ +Y+ PE+++ + +D++ DLWSLG++ Y L G PPF
Sbjct: 1614 GTKTPELLTPVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILYIMLCGYPPFYGQCG 1435
Query: 335 QET---------------YKRISRVEFTFPD----FVTEGARDLISRLLKHNPSQRPMLR 375
++ + I + FP ++ A+DLI LL P +R
Sbjct: 1434 EDCGWNRGEACHDCQDMLFNSIQDGHYKFPSQEWTSISSSAKDLIRHLLVREPRKRYSAA 1255
Query: 376 EVLEHPWIT 384
+VL+HPWI
Sbjct: 1254 DVLKHPWIC 1228
>01756
Length = 1858
Score = 87.0 bits (214), Expect = 1e-17, Method: Compositional matrix adjust.
Identities = 66/222 (29%), Positives = 106/222 (47%), Gaps = 16/222 (7%)
Frame = -3
Query: 139 LGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYG 198
+G+G FG V+ AR K++K ++A+K + EK G RE++I L H N++ L
Sbjct: 1718 IGQGTFGEVFKARCKKTKQVVAMKKVLMDN-EKEGFPITALREIKILQLLNHENVVDLIE 1542
Query: 199 YFH----DATR----VYLILEYA--PLGTVYRELQKLSKFDEQRTATYITELANALSYCH 248
A R YL+ E+ L + + + E + + +L N L Y H
Sbjct: 1541 ICSTKATSANRYKSMFYLVFEFCEHDLAGLLSNMSVVFNLPEIKEV--MKQLMNGLYYIH 1368
Query: 249 SKRVIHRDIKPENLLLGSAGELKIADFG----WSVHAPS-SRRTTLCGTLDYLPPEMIEG 303
+++HRD+K N+L+ G LK+ADFG +SV+ +R T TL Y PPE++ G
Sbjct: 1367 RNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRPPELLLG 1188
Query: 304 -RMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRV 344
R + +D W G + E P + T Q I+++
Sbjct: 1187 DRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQNQLTLITQL 1062
>13066
Length = 551
Score = 87.0 bits (214), Expect = 1e-17, Method: Compositional matrix adjust.
Identities = 50/164 (30%), Positives = 87/164 (53%), Gaps = 6/164 (3%)
Frame = +3
Query: 159 LALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTV 218
LA K++ K + VE RE+++ + L HP I++++ + ++ + +A G +
Sbjct: 60 LACKIIDKEKAPVDFVEKFFPRELDLLTKLDHPYIIQIHSILQRXPKNFIFMRFAERGDL 239
Query: 219 YRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS 278
+Q++ E++ + ++ AL+Y HS V HRD+K EN+LL S +K+ADFG++
Sbjct: 240 LTYIQEVGFVKEKQAKIWFYQMTTALNYLHSYDVAHRDLKCENILLSSHFNVKLADFGFA 419
Query: 279 VHAPSS-----RRTTLCGTLDYLPPEMIEGRMHDEKV-DLWSLG 316
+ T CG+ Y PE++ G + KV D WSLG
Sbjct: 420 CACITESGEKYMSRTYCGSAAYAAPEIVYGAPYAPKVADAWSLG 551
>11780
Length = 1713
Score = 80.1 bits (196), Expect(2) = 2e-17, Method: Compositional matrix adjust.
Identities = 57/202 (28%), Positives = 100/202 (49%), Gaps = 7/202 (3%)
Frame = +3
Query: 121 EESKKRQW--ALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQL 178
+E K W A +D EIG +GKG FG+VY + V K +K E
Sbjct: 561 QEFKSGGWVIAXQDLEIGEAIGKGDFGDVYKGMYRGQP------VAIKQLKDKDRGEQSF 722
Query: 179 RREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSK--FDEQRTATY 236
+E + + LRH N++RL G T ++L+ E+ G + L+ + ++ +
Sbjct: 723 LQEASVMTSLRHDNLVRLIGVVLGET-IFLVTEFMGKGNLVEYLRSRGRSVITKKDQINF 899
Query: 237 ITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYL 296
T+ A+ Y SKR++HRD+ N+L+ G+ K++DFG + S +T++ + +
Sbjct: 900 ATDTCAAMEYLESKRLVHRDLAARNVLVHDDGKAKVSDFGLAKFGDFS-QTSVKFPIKWT 1076
Query: 297 PPEMI-EGRMHDE--KVDLWSL 315
PE + E ++H + V+LW +
Sbjct: 1077APEALRENKIH*QVRHVELWHI 1142
Score = 26.6 bits (57), Expect(2) = 2e-17, Method: Compositional matrix adjust.
Identities = 16/72 (22%), Positives = 33/72 (45%), Gaps = 2/72 (2%)
Frame = +1
Query: 309 KVDLWSLGVLCYE-FLVGKPPFEANTYQETYKRISR-VEFTFPDFVTEGARDLISRLLKH 366
K D+WS G+L +E + G+ P+ + + R P+ ++ + +
Sbjct: 1114 KSDMWSFGILLWEIYSFGRVPYPRIPLTDVVMHVERGYRMEAPEGCPPEIYSIMKQAWEL 1293
Query: 367 NPSQRPMLREVL 378
+P++RP + VL
Sbjct: 1294 DPNERPTFKSVL 1329
>04591
Length = 1117
Score = 86.3 bits (212), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 60/184 (32%), Positives = 88/184 (47%), Gaps = 12/184 (6%)
Frame = -2
Query: 171 KAGVEHQLRREVEIQSHLRHPNILRLYGYFHD--------ATRVYLILEYAP--LGTVYR 220
K G RE++I L H N+++L H + YLI EY L +
Sbjct: 1101 KEGFPITALREIKILQQLEHENVVQLQEICHTQAGPYNRYKSTFYLIFEYCDYDLAGLLN 922
Query: 221 ELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSV- 279
L+ KF +++L N L Y H+K+++HRDIK N+LL G LK+ADFG S
Sbjct: 921 NLR--VKFSLADKKNLMSQLLNGLFYIHTKQILHRDIKAANILLTRDGVLKLADFGLSRP 748
Query: 280 HAPSSRRTTLCGTLDYLPPEMIEG-RMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETY 338
S R T TL Y PPE++ G R + ++D+W +G + E KP + + Q
Sbjct: 747 WVKSKRLTNRVVTLWYRPPELLLGEREYGPEIDMWGVGCIMAEMWSRKPLMQGRSEQHQL 568
Query: 339 KRIS 342
I+
Sbjct: 567 SLIT 556
>01718
Length = 959
Score = 85.9 bits (211), Expect = 3e-17, Method: Compositional matrix adjust.
Identities = 62/209 (29%), Positives = 99/209 (47%), Gaps = 11/209 (5%)
Frame = +3
Query: 130 LEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLR 189
L+DF I +G G F V+ + + ++ALK+ H + REV++ + L+
Sbjct: 147 LDDF-ICEKIGAGFFSEVFKVTHRITGQVMALKMN-----TMTSNRHNMLREVQLLNRLQ 308
Query: 190 HPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTAT----YITELANALS 245
H NILR G +++ + EY P G + Q L K DE+ T LA L
Sbjct: 309 HANILRFMGVCVHEGQLHALTEYIPSGNLE---QLLEKKDEELPWTQRIQLTLGLARGLD 479
Query: 246 YCHSKRVIHRDIKPENLLL----GSAGELKIADFGWSVHAP---SSRRTTLCGTLDYLPP 298
Y HS R IHRD+ +N+L+ IADFG + P + G+ ++ P
Sbjct: 480 YLHSTRFIHRDLTSKNILIRREDNHGYHAVIADFGLATKIPDPLDKEKLPTVGSPYWMAP 659
Query: 299 EMIEGRMHDEKVDLWSLGVLCYEFLVGKP 327
E++ G ++E+ DL+S+G++ E P
Sbjct: 660 EVLNGHFYNERADLFSVGIIMCEITARIP 746
>17975
Length = 449
Score = 85.1 bits (209), Expect = 4e-17, Method: Compositional matrix adjust.
Identities = 51/137 (37%), Positives = 80/137 (58%), Gaps = 2/137 (1%)
Frame = +3
Query: 144 FGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDA 203
F V LAR + +A+KV+ K +L++ H L +EV ++HPN++RLY
Sbjct: 6 FAVVKLARHVFTGEKVAVKVIDKTKLDEVSRSH-LFQEVRCMKLVQHPNVVRLYEVIDTQ 182
Query: 204 TRVYLILEYAPLGTVYRELQKLSKFDEQRTAT-YITELANALSYCHSKRVIHRDIKPENL 262
T++YLILE G +Y + + S E++ A Y ++ A+SYCH V+HRD+KPEN+
Sbjct: 183 TKLYLILELGDGGDMYDYIMRHSGGLEEKLAKRYFRQIVEAISYCHKLHVVHRDLKPENV 362
Query: 263 LLGSA-GELKIADFGWS 278
+ G +K+ DFG+S
Sbjct: 363 VFFEKPGLVKLTDFGFS 413
>31885
Length = 529
Score = 84.3 bits (207), Expect = 7e-17, Method: Compositional matrix adjust.
Identities = 48/158 (30%), Positives = 81/158 (51%), Gaps = 6/158 (3%)
Frame = -2
Query: 182 VEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELA 241
V++ + L HP ++ L+ F D ++++++ G + +Q+ F E Y+ +LA
Sbjct: 519 VDMLTRLDHPFLVNLWYAFQDEEDLFMVVDLFLGGDLRYHMQQEVSFREDCVKFYLCQLA 340
Query: 242 NALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSR-RTTLCGTLDYLPPEM 300
L Y S++++HRDIKP+N+LL G + DF + T+ GT Y+ PE+
Sbjct: 339 LVLDYLRSQKIVHRDIKPDNILLDEQGHCHVTDFNIATQLEDDELATSTSGTRPYMAPEV 160
Query: 301 I-----EGRMHDEKVDLWSLGVLCYEFLVGKPPFEANT 333
E R + VD WSLGV +E L + PF ++
Sbjct: 159 YGVAINERRGYGFPVDWWSLGVSLFELLKKRRPFSVHS 46
>27546
Length = 426
Score = 82.8 bits (203), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 42/120 (35%), Positives = 70/120 (58%)
Frame = -1
Query: 159 LALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTV 218
LA K++ KA+ V+ RE+EI + L HPNI++++ ++++ + YA G +
Sbjct: 396 LACKIIDKAKAPIDFVKKFFPRELEILTRLDHPNIIQIHSILQRGPKIFIFMRYAEKGDM 217
Query: 219 YRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS 278
++K DE +T + ++A AL Y HS + HRD+K EN+LL +KIADFG++
Sbjct: 216 LSHIKKTGPIDEAQTKVWFFQMAKALQYLHSHDIAHRDLKCENILLSKRLNVKIADFGFA 37
>00486
Length = 797
Score = 82.0 bits (201), Expect = 3e-16, Method: Compositional matrix adjust.
Identities = 35/84 (41%), Positives = 53/84 (63%)
Frame = -2
Query: 288 TLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFT 347
T CGT++Y+ PE++ H + VD WSLG L Y+ L G PPF A ++T +I + +
Sbjct: 781 TFCGTIEYMAPEILTRTGHGKAVDWWSLGALMYDMLTGSPPFTAENRKKTIDKILKGKLN 602
Query: 348 FPDFVTEGARDLISRLLKHNPSQR 371
P ++T AR LI +LL+ NP++R
Sbjct: 601 LPPYLTNEARGLIKKLLRKNPAER 530
>21079
Length = 878
Score = 81.6 bits (200), Expect = 6e-16, Method: Compositional matrix adjust.
Identities = 42/148 (28%), Positives = 79/148 (53%), Gaps = 4/148 (2%)
Frame = +1
Query: 190 HPNILRLYGYFHDATRVYLILEYAPLGTVY-RELQKLSKFDEQRTATYITELANALSYCH 248
HP +L L+ F + L++E+ G ++ R ++ E+ ++ ++ + + Y H
Sbjct: 1 HPKLLMLWDAFEAPRTMVLVMEFVGAGELFERVIRDDFVLTERDCVHFVRQICSGVGYMH 180
Query: 249 SKRVIHRDIKPENLLLGS--AGELKIADFGWS-VHAPSSRRTTLCGTLDYLPPEMIEGRM 305
++ ++H D+KPEN+L S + ++KI DFG + + P L GT +++ PE++
Sbjct: 181 TQSILHLDLKPENVLCVSDNSNQIKIIDFGLARFYKPGDSLQVLFGTPEFIAPEVVNYDE 360
Query: 306 HDEKVDLWSLGVLCYEFLVGKPPFEANT 333
+ D+WS+GV+CY L G P T
Sbjct: 361 INFTTDMWSIGVICYILLSGLSPSRVTT 444
>00392
Length = 668
Score = 80.5 bits (197), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 48/175 (27%), Positives = 91/175 (52%), Gaps = 9/175 (5%)
Frame = +3
Query: 177 QLRREVEIQSHLRHPNILRLYGYFHDATR-----VYLILEYAPLGTVYRELQKLSKFDEQ 231
+ + E E+ L+HPNI+R + Y+ + + L+ E GT+ L++ K + +
Sbjct: 69 RFKEEAEMLKELQHPNIVRFFDYWEEHNHRNRKVIILVTELMTSGTLKTYLKRFKKPNVK 248
Query: 232 RTATYITELANALSYCHSKR--VIHRDIKPENLLL-GSAGELKIADFGWSVHAPSSRRTT 288
+ ++ L + H++ VIHRD+K +N+ + G G +KI D G + S +
Sbjct: 249 ILKNWCRQVLKGLYFLHTRTPPVIHRDLKCDNIFITGPTGSVKIGDLGLATLKNQSFAKS 428
Query: 289 LCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPF-EANTYQETYKRIS 342
+ GT +++ PEM E +DE VD+++ G+ E + P+ E + + YKR++
Sbjct: 429 VIGTPEFMAPEMYEEH-YDEAVDVYAFGMCMLEMASSEYPYSECSNAAQIYKRVT 590
>01966
Length = 1735
Score = 79.0 bits (193), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 42/135 (31%), Positives = 70/135 (51%), Gaps = 4/135 (2%)
Frame = -1
Query: 173 GVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEY--APLGTVYRELQKLSKFDE 230
GV RE+ + LRH NI+ L + R++L+ E+ L + + D
Sbjct: 1588 GVPSSAIREIAMLRELRHTNIVCLEDVIMEDERLFLVFEFLSMDLKMYIDKFPEGVVLDR 1409
Query: 231 QRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGW--SVHAPSSRRTT 288
+ +Y+ ++ +++CH +R++HRD+KP+NLL+ G +KIADFG + P T
Sbjct: 1408 RLVKSYVFQIVTGINFCHQRRIVHRDLKPQNLLINHTGAIKIADFGMARTFALPVRAYTH 1229
Query: 289 LCGTLDYLPPEMIEG 303
TL Y PE++ G
Sbjct: 1228 EVVTLWYRAPEILMG 1184
>19761
Length = 473
Score = 76.3 bits (186), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 40/142 (28%), Positives = 77/142 (54%), Gaps = 4/142 (2%)
Frame = -3
Query: 230 EQRTATYITELANALSYCHSKR--VIHRDIKPENLLLGSAGELKIADFGWS--VHAPSSR 285
E+ ++ + A+AL+Y H+ ++HRD+KP+N+ + G++++ D G + + P+
Sbjct: 426 ERLIVCWLMQTASALNYMHTHTPVILHRDLKPQNIYVTEKGDVRLGDLGLARKLTGPADF 247
Query: 286 RTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVE 345
T+ GT+ YL PE++ + ++ K D+WSLG + Y+ K E + + +
Sbjct: 246 ATSQVGTIMYLSPEILSQQPYNSKSDIWSLGCVFYDITGKKGSDEMGVMFLLVQVMGGRK 67
Query: 346 FTFPDFVTEGARDLISRLLKHN 367
PD ++ RD ISR+L +
Sbjct: 66 LPLPDHYSQEFRDTISRMLTKD 1
>19094
Length = 898
Score = 70.1 bits (170), Expect(2) = 6e-14, Method: Compositional matrix adjust.
Identities = 39/103 (37%), Positives = 57/103 (55%), Gaps = 2/103 (1%)
Frame = +1
Query: 230 EQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS--VHAPSSRRT 287
E+ AT + L Y HS+R IHRDIK N+LL + G K+ADFG + + ++R
Sbjct: 55 EREIATILYYTLKGL*YLHSRRKIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRN 234
Query: 288 TLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFE 330
T+ GT ++ PE+I+ +D D+WSLG+ E G E
Sbjct: 235 TVIGTPYWMAPEVIQEIGYDCVADIWSLGITALEMAEGNLHME 363
Score = 24.6 bits (52), Expect(2) = 6e-14, Method: Compositional matrix adjust.
Identities = 12/38 (31%), Positives = 19/38 (50%)
Frame = +3
Query: 346 FTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWI 383
F PD + D +S+ L NP R ++L+H +I
Sbjct: 417 FRQPDKWSTEFIDFVSKCLVKNPENRATAVDLLQHDFI 530
>26560
Length = 398
Score = 74.7 bits (182), Expect = 7e-14, Method: Composition-based stats.
Identities = 40/131 (30%), Positives = 67/131 (51%), Gaps = 1/131 (0%)
Frame = -1
Query: 218 VYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGW 277
++ L + F E+ Y E+ L + HS+ V++RD+KP N+LL G ++I+D G
Sbjct: 395 LHYHLSQHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGL 216
Query: 278 SVHAPSSRRTTLCGTLDYLPPE-MIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQE 336
+ R GT Y+ PE +++G+ +D D +S G + Y+ L G PF + +
Sbjct: 215 ACDFSKKRPHASVGTHGYMAPEVLMKGQSYDSSADWFSFGCMLYKLLKGHSPFR--QHNQ 42
Query: 337 TYKRISRVEFT 347
RI R+ T
Sbjct: 41 GQARIDRMTMT 9
>29581
Length = 1278
Score = 72.0 bits (175), Expect = 4e-13, Method: Compositional matrix adjust.
Identities = 63/235 (26%), Positives = 101/235 (42%), Gaps = 38/235 (16%)
Frame = -2
Query: 187 HLRHPNILRL----YGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELAN 242
+LRH NI++L G D+ ++L++EY + F E + + +L
Sbjct: 1187 NLRHQNIVQLQEVVVGKSLDS--LFLVMEYCEQDLASLLDNMPAPFSESQVKCIVLQLLK 1014
Query: 243 ALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVH--APSSRRTTLCGTLDYLPPEM 300
L Y H +IHRD+K NLL+ G +KIADFG + + P T TL Y PE+
Sbjct: 1013 GLRYLHEAFIIHRDLKVSNLLMTDKGCVKIADFGLARNYGKPQKPMTPKVVTLWYRAPEL 834
Query: 301 IEG-RMHDEKVDLWSLGVLCYEFLVGKPPFEANT-------------------------- 333
+ G + H +D+WS G + E L KP +
Sbjct: 833 LFGSKTHSTAIDMWSAGCILGELLGHKPLMPGRSDLQQIELIMELLGTPNDTIWPGFSQL 654
Query: 334 ---YQETYKR--ISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWI 383
Q T K+ + + TFP +++E L++ L ++P +R + LEH +
Sbjct: 653 PAFEQFTLKKQPYNNLRHTFP-WLSESGIRLLNGLFMYHPQKRATAEDCLEHSYF 492
>20152
Length = 445
Score = 68.9 bits (167), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 32/96 (33%), Positives = 50/96 (52%), Gaps = 1/96 (1%)
Frame = +1
Query: 298 PEMIEGRMHDE-KVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGA 356
PE++ G +D VD+WSLGV+ Y +VG+ PF+ ET I + P ++
Sbjct: 1 PEILLGDSYDAPAVDVWSLGVILYMLVVGEAPFQEANDSETLTMIMDCRYQIPPHISHKC 180
Query: 357 RDLISRLLKHNPSQRPMLREVLEHPWITANSSKPSN 392
+DLI ++L+ P R L +L HPW+ P+
Sbjct: 181 QDLIEKMLQREPVDRASLPHILAHPWLNDGDLTPTT 288
>27405
Length = 532
Score = 67.8 bits (164), Expect = 7e-12, Method: Compositional matrix adjust.
Identities = 47/175 (26%), Positives = 84/175 (48%), Gaps = 5/175 (2%)
Frame = -3
Query: 144 FGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLR----HPNILRLYGY 199
FG VY R+ + + A+K L K +++ G E E + S + P I+ +
Sbjct: 527 FGEVYGCRKADTGKMYAMKCLDKKRIKMKGGETLALNERIMLSLVSTGEGSPFIVCMTYA 348
Query: 200 FHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKP 259
F ++ IL+ G ++ L + F E+ Y E+ L + HS+ V++RD+KP
Sbjct: 347 FQTPEKLCFILDLMNGGDLHYHLSQHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKP 168
Query: 260 ENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPE-MIEGRMHDEKVDLW 313
N+LL G ++I+D G + + GT Y+ PE +++G+ +D D +
Sbjct: 167 ANILLDENGHVRISDLGLACDFSKKKPHASVGTHGYMAPEVLMKGQAYDSSADWF 3
>26711
Length = 405
Score = 65.9 bits (159), Expect = 3e-11, Method: Composition-based stats.
Identities = 39/132 (29%), Positives = 72/132 (54%), Gaps = 8/132 (6%)
Frame = -2
Query: 237 ITELANALSYCHSKRVIHRDIKPENLLLG--SAGELKIADFGWSVHAPSSRRTTLC-GTL 293
+ ++ + L + H++ V+H D+KP NLLL +++ DFG + + T L GT
Sbjct: 398 VKQVLDILQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARKLYPPQETFLNHGTP 219
Query: 294 DYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTF---PD 350
+ PE ++ + D+W +GVL Y L G+ PF+A++ E+ K+ +++F P
Sbjct: 218 GFTSPEALDVKPISTASDVWGVGVLAYILLSGQSPFQADSATESLKKTQTCDWSFDVCPS 39
Query: 351 F--VTEGARDLI 360
F +++ A+D I
Sbjct: 38 FSNMSQDAKDFI 3
>19301
Length = 712
Score = 65.1 bits (157), Expect = 5e-11, Method: Compositional matrix adjust.
Identities = 33/101 (32%), Positives = 56/101 (55%), Gaps = 2/101 (1%)
Frame = +2
Query: 180 REVEIQS--HLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYI 237
+E +I++ L HPNI+ G A +I+EY P G +Y L+ + +
Sbjct: 410 KETDIRNLRKLNHPNIISFKGVCTQAPCYCIIMEYCPYGQLYEVLRDGKEIPPALVLDWS 589
Query: 238 TELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS 278
++A+ ++Y HS ++IHRD+K N+L+ +KI+DFG S
Sbjct: 590 KQIASGMNYLHSHKIIHRDLKSPNVLVAKNDVVKISDFGTS 712
>38560
Length = 479
Score = 64.7 bits (156), Expect = 6e-11, Method: Compositional matrix adjust.
Identities = 33/111 (29%), Positives = 58/111 (52%), Gaps = 1/111 (0%)
Frame = -3
Query: 287 TTLCGTLDYLPPEMIEGRMH-DEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVE 345
TT CG+ Y PE+I G + + D+WS+GVL Y L G PF+ ++ + +
Sbjct: 411 TTCCGSPAYAAPELISGLEYLGSEADIWSMGVLLYALLCGYLPFDDEKXSHL*QKNQKRK 232
Query: 346 FTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQNK 396
P++++E L+ +L+ +PS R +R +L+H W+ + P +K
Sbjct: 231 DEVPEWLSEDTTKLLEGMLQTDPSHRITIRRLLDHHWLNQGFNVPVEWASK 79
>14477
Length = 493
Score = 63.9 bits (154), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 44/142 (30%), Positives = 73/142 (51%), Gaps = 2/142 (1%)
Frame = -1
Query: 139 LGKGKFGNVY--LAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRL 196
LG G FG+V + R + +A+KVL A L+ + V+ +L +E E+ + H +I+RL
Sbjct: 466 LGAGNFGSVMKGVCRLDDREIPVAIKVLKNADLDPS-VQSELIKEAEVMKKMDHMHIVRL 290
Query: 197 YGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRD 256
G T + L+LE A LG + + L K + +++ + Y + + +HRD
Sbjct: 289 IGLCEGET-MMLVLELAKLGPLNKFLPKNKHLPLWNILELMWQVSQGMEYLEANKFVHRD 113
Query: 257 IKPENLLLGSAGELKIADFGWS 278
+ N+LL KI+DFG S
Sbjct: 112 LAARNILLCDEHFAKISDFGMS 47
>04852
Length = 1462
Score = 63.9 bits (154), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 40/151 (26%), Positives = 75/151 (49%), Gaps = 5/151 (3%)
Frame = +1
Query: 235 TYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTL- 293
+Y ++A + + S++ IHRD+ N+L+ LKIADFG S ++ + G L
Sbjct: 337 SYAFQIARGMEFLASRKCIHRDLAARNVLVTEEHVLKIADFGLSRTGDYYKKRS-GGRLP 513
Query: 294 -DYLPPEMIEGRMHDEKVDLWSLGVLCYE-FLVGKPPFEANTYQETYKRISRVEFTF--P 349
++ PE + + K D+WS GV+ +E F +G P+ + +E Y ++ + P
Sbjct: 514 VKWMAPEALFDMRYTTKSDVWSFGVVLWEIFSLGGMPYASIPNEELYSKLLDDAYRMPRP 693
Query: 350 DFVTEGARDLISRLLKHNPSQRPMLREVLEH 380
+ + ++ R + PS RP +++ H
Sbjct: 694 ELASGNLYAIMERCWLNRPSDRPEFSQLVGH 786
>06358
Length = 1517
Score = 63.5 bits (153), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 65/273 (23%), Positives = 121/273 (44%), Gaps = 40/273 (14%)
Frame = +3
Query: 140 GKGKFGNVYLAREKQSK-----FILALKVLFK-AQLEKAGVEHQLRREVEIQSHLRHPNI 193
G G V+ A +K +K F+ K + + ++ ++ + LR V+ + LRHP I
Sbjct: 33 GPGLLWKVFAASKKSTKEEASVFVFEKKSVDRYSRRDREAIVEVLRVGVQQLTKLRHPKI 212
Query: 194 LRLYGYFHD-------------ATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITEL 240
L + + A+ ++ + + + TV +ELQ +D + + ++
Sbjct: 213 LAVINPLEESRETLAFATEPVFASLANVLGDLSSIXTVPKELQDYQLYDVE-IKHGLLQV 389
Query: 241 ANALSYCHSK-RVIHRDIKPENLLLGSAGELKIADFGWSVHA--PSSR---------RTT 288
AL + H+ +++HR++ PE ++L G K+A + + V + P S R+
Sbjct: 390 TEALGFLHNDAKMMHRNVCPEAIMLTKLGSWKLAGYEFCVRSSDPQSTDPSYPFYEWRSD 569
Query: 289 LCGT----LDYLPPEMIEGRMHDEKVDLWSLGVLCYE-FLVGKPPFEAN----TYQETYK 339
+ LD++ PE + D++SLG+L Y F GKP FE N ++ +
Sbjct: 570 IAPVTQPHLDFMAPEYVLTMQCGTGSDMFSLGLLVYSVFAKGKPLFECNGELSAFKSNAE 749
Query: 340 RISRVEFTFPDFVTEGARDLISRLLKHNPSQRP 372
+ + + V E RD + LL P+ RP
Sbjct: 750 ELRHMRVSLLGVVPEDLRDHVKLLLNIEPAVRP 848
>04138
Length = 800
Score = 63.5 bits (153), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 51/177 (28%), Positives = 72/177 (40%), Gaps = 40/177 (22%)
Frame = +1
Query: 244 LSYCHSKRVIHRDIKPENLLLGSAGELKIADFG----WSVHAPS-SRRTTLCGTLDYLPP 298
L Y H +++HRD+K N+L+ G LK+ADFG +SV+ +R T TL Y PP
Sbjct: 52 LYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRPP 231
Query: 299 EMIEG-RMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGAR 357
E++ G R + +D W G + E P + T Q I+++ + V G
Sbjct: 232 ELLLGDRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQNQLTLITQLCGSITPEVWPGVT 411
Query: 358 ----------------------------------DLISRLLKHNPSQRPMLREVLEH 380
DL RLLK +PSQR E L H
Sbjct: 412 QLSMYHQIKGALAAGRKNIIRDRFARILKDPYGLDLFERLLKMDPSQRISADEALNH 582
>21808
Length = 1011
Score = 63.2 bits (152), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 43/166 (25%), Positives = 73/166 (43%), Gaps = 5/166 (3%)
Frame = +1
Query: 181 EVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYI-TE 239
E +I LRHP +++LY +++I E G++ LQ + + I +
Sbjct: 82 EAQIMKKLRHPKLIQLYAVCTQDDPIFIITELMKNGSLLEFLQGKGRVLKLPALIDIGAQ 261
Query: 240 LANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGT---LDYL 296
+A ++Y S+ IHRD+ N+L+ +KIADFG + G + +
Sbjct: 262 IACGMAYLESQNYIHRDLAARNILVSDNNTVKIADFGLARVIKEDEYEARVGARFPIKWT 441
Query: 297 PPEMIEGRMHDEKVDLWSLGVLCYEFLV-GKPPFEANTYQETYKRI 341
PE K D+WS G+L E + G+ P+ T E ++
Sbjct: 442 APEAANYNRFTIKSDVWSFGILLTETVTYGRVPYPGMTNAEVLHQV 579
>00715
Length = 1788
Score = 61.6 bits (148), Expect = 5e-10, Method: Compositional matrix adjust.
Identities = 47/177 (26%), Positives = 76/177 (42%), Gaps = 33/177 (18%)
Frame = +1
Query: 188 LRHPNILRLYGY-----FHDATRVYLILEYAP---LGTVYRELQKLSKFDEQRTATYITE 239
LRH N++ + G F D +L +EY L T+ + Q+ D + +
Sbjct: 97 LRHVNVVSILGATSLHRFEDGA--WLAMEYVGPLNLQTILNDHQQ--DIDSSMRLSLALQ 264
Query: 240 LANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVH------------------- 280
+A L Y HS ++H D+KP N LL +L+IADFG H
Sbjct: 265 MARGLHYLHSINIVHLDLKPANCLLTRDLKLRIADFG-CCHQLTPTGLDMGEREGGMAGN 441
Query: 281 ------APSSRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEA 331
+ + L GTL Y PE+++G + D++SLG+ ++ + P+E
Sbjct: 442 ELELTPVQGAWKNELAGTLAYRAPELLKGLQPSVRSDVYSLGITLWQMCTRQGPYEG 612
>14116
Length = 1017
Score = 61.2 bits (147), Expect = 6e-10, Method: Compositional matrix adjust.
Identities = 56/217 (25%), Positives = 96/217 (44%), Gaps = 24/217 (11%)
Frame = -1
Query: 131 EDFEIGRPLGKGKFGNV---YLAR-EKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQS 186
E +G +GKG FG V +L E++ ++A+K L RE+E+QS
Sbjct: 636 EFLTMGEEIGKGNFGCVKRGFLTLPEQKGDILVAVKTLHNNN----------PREIELQS 487
Query: 187 HLR---------HPNILRLYGY---FHDATRVYL-ILEYAPLGTVYRELQKLSKFDEQRT 233
L+ H N+L L G D V L +++ L T R+ Q +
Sbjct: 486 FLQEALIMKDFHHSNVLTLIGICLNLDDMPLVVLPFMKHGDLLTYIRDDQHQPTIKD--L 313
Query: 234 ATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS-------VHAPSSRR 286
Y ++A + Y + +HRD+ N +L +K+ADFG + ++ +++
Sbjct: 312 IMYGVDIARGMDYLAGLKFVHRDLAARNCMLDEDFHVKVADFGLARDIYEKEYYSSENKK 133
Query: 287 TTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFL 323
L + ++ E +E +D K D+WS GV+ +E L
Sbjct: 132 AKL--PVKWMALESLEKGNYDSKTDVWSYGVVLWELL 28
>28157
Length = 400
Score = 61.2 bits (147), Expect = 8e-10, Method: Compositional matrix adjust.
Identities = 39/104 (37%), Positives = 57/104 (54%), Gaps = 7/104 (6%)
Frame = +3
Query: 180 REVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLS---KFDEQRTATY 236
+E++ S + HPNI+ LYG D V L++EYA G++Y L ++ +
Sbjct: 57 QELKQLSRVSHPNIVCLYGACRDHP-VCLVMEYAEGGSLYNVLHGSGPQPQYTAAHAMNW 233
Query: 237 ITELANALSYCHS---KRVIHRDIKPENLLLGSAG-ELKIADFG 276
+ + A + Y H K +IHRD+KP NLLL G +LKI DFG
Sbjct: 234 LLQCALGVEYLHGMKPKALIHRDLKPPNLLLIQCGTKLKICDFG 365
>12672
Length = 773
Score = 60.8 bits (146), Expect = 9e-10, Method: Compositional matrix adjust.
Identities = 45/161 (27%), Positives = 69/161 (42%), Gaps = 24/161 (14%)
Frame = +3
Query: 241 ANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTT------LCGTLD 294
A+ + Y + +HRDIK N+LL S K+ DF V APS T + GT
Sbjct: 21 ASGIQYLNDNGHVHRDIKTANILLDSEYTAKVGDFATVVSAPSGEGKTVQNASVVIGTAA 200
Query: 295 YLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTY------------------QE 336
YL PE I + K+D +S GV+ E + G A Y +E
Sbjct: 201 YLAPEAIHFDVS-TKLDSYSFGVVLLEVITG---LVAQDYSREERTLSSHIMENVEEPEE 368
Query: 337 TYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREV 377
+ + + T+PD + D+ R L + QRP ++++
Sbjct: 369 IHDFVDQSAGTWPDGAVDKLYDISMRCLNLSKKQRPNVKDI 491
>07940
Length = 1336
Score = 60.8 bits (146), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 36/100 (36%), Positives = 54/100 (54%), Gaps = 5/100 (5%)
Frame = -3
Query: 235 TYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS--VHAPSSRRTTLCGT 292
+Y ++A + Y SK+ IHRD+ N+L+ LKIADFG + + R T G
Sbjct: 335 SYAYQVARGMEYLASKQCIHRDLAARNVLVAEEYVLKIADFGLTRNLQQFDYYRKTTDGR 156
Query: 293 L--DYLPPEMIEGRMHDEKVDLWSLGVLCYE-FLVGKPPF 329
L ++ PE + R + K D+WS GVL +E F +G P+
Sbjct: 155 LPVKWMAPEALFDRKYTSKSDVWSYGVLLWEIFTLGGNPY 36
Score = 34.3 bits (77), Expect = 0.088, Method: Compositional matrix adjust.
Identities = 28/95 (29%), Positives = 49/95 (51%), Gaps = 7/95 (7%)
Frame = -3
Query: 131 EDFEIGRPLGKGKFGNVYLAREKQSKF------ILALKVLFKAQLEKAGVEHQLRREVEI 184
E +G LG+G FG V + E F +A+K+L + ++ ++ L RE+E+
Sbjct: 842 ERLVLGDRLGEGAFGLV-MKGEAMGIFKDNNSVTVAVKMLKEDATDREMMD--LIREMEM 672
Query: 185 QSHL-RHPNILRLYGYFHDATRVYLILEYAPLGTV 218
+ +H NI+ L G +Y+I+E+AP G +
Sbjct: 671 MKVIGKHKNIINLLGCCTQRGALYVIVEFAPHGNL 567
>03508
Length = 1463
Score = 60.8 bits (146), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 31/109 (28%), Positives = 57/109 (52%), Gaps = 3/109 (2%)
Frame = +1
Query: 223 QKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAG-ELKIADFGWS-VH 280
Q F + Y+ EL AL +CHS ++HRD+KP N+++ +L++ D+G + +
Sbjct: 847 QLYQTFTDYDIRFYLYELMKALDFCHSMGIMHRDVKPHNVMIDHENKKLRLIDWGLAEFY 1026
Query: 281 APSSRRTTLCGTLDYLPPE-MIEGRMHDEKVDLWSLGVLCYEFLVGKPP 328
P + + PE +++ +M+D +D+WSLG + + K P
Sbjct: 1027HPGMEYNVRVASRYFKGPELLLDYQMYDYSLDMWSLGCMFASMIFRKEP 1173
>26009
Length = 886
Score = 40.8 bits (94), Expect(2) = 3e-09, Method: Compositional matrix adjust.
Identities = 17/49 (34%), Positives = 30/49 (61%)
Frame = +3
Query: 216 GTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLL 264
GT ++ + + + +L +AL + HSK+++HRDIKPEN+L+
Sbjct: 666 GTCLTPSRRNKACGSREAKSVMKQLVSALDFMHSKQLVHRDIKPENVLI 812
Score = 38.1 bits (87), Expect(2) = 3e-09, Method: Compositional matrix adjust.
Identities = 26/91 (28%), Positives = 47/91 (51%), Gaps = 2/91 (2%)
Frame = +2
Query: 131 EDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLR- 189
E +++ + LG+G +G V LAR + + +ALK+L K+ + + +RE ++ L
Sbjct: 416 EHYDVCKELGRGTYGKVVLARCRHTGTQVALKLLPKSCTKL----REFQREFQLSYFLSP 583
Query: 190 HPNILRLYGY-FHDATRVYLILEYAPLGTVY 219
H NI+ Y F + E+A LG ++
Sbjct: 584 HANIIDTYNVAFQTRSSYVFAQEHAVLGDLF 676
>12786
Length = 460
Score = 58.9 bits (141), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 37/127 (29%), Positives = 54/127 (42%), Gaps = 24/127 (18%)
Frame = -3
Query: 228 FDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRT 287
D Y E+ A+ H++ VIH D+KP N +L AG LK+ DFG + + +
Sbjct: 419 LDRMMIKFYWREMLRAVKALHNEGVIHSDLKPANFML-VAGNLKLIDFGIANTLQQDKTS 243
Query: 288 TL----CGTLDYLPPEMIEGRMHDE--------------------KVDLWSLGVLCYEFL 323
L GT Y+ PE I D + D+WSLG + Y +
Sbjct: 242 VLKDSRVGTPSYMSPEAIMAACDDSADDSMEEDGHRTKPKYKVGVRSDVWSLGCILYNMV 63
Query: 324 VGKPPFE 330
G+ PF+
Sbjct: 62 YGRTPFQ 42
>18663
Length = 600
Score = 57.8 bits (138), Expect = 7e-09, Method: Compositional matrix adjust.
Identities = 32/112 (28%), Positives = 52/112 (46%), Gaps = 15/112 (13%)
Frame = +2
Query: 287 TTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEA---------NTYQET 337
+T CGT +Y+ PE++ G + VD W+LGVL YE L G+ PF+ NT
Sbjct: 2 STFCGTPNYIAPEILRGEDYGFSVDWWALGVLLYEMLAGRSPFDIAGASENPDQNTEDYL 181
Query: 338 YKRISRVEFTFPDFVTEGARDLISRLLKHNPSQR------PMLREVLEHPWI 383
++ I P ++ A ++ L NP+ R +++ HP+
Sbjct: 182 FQVILEKTIRIPRSLSVKAASVLKGFLNKNPADRLGCHRESAFMDIVNHPFF 337
>28638
Length = 1458
Score = 55.8 bits (133), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 41/132 (31%), Positives = 60/132 (45%), Gaps = 5/132 (3%)
Frame = -1
Query: 203 ATRVYLILEYAP-LGTVYRELQKLSKFDEQRTATYITELANALSYCHS--KRVIHRDIKP 259
AT L +P + T Q L T + +L AL + + +IH D+KP
Sbjct: 924 ATTCVWCLSCSPTISTTCYATQTLEGVSLNLTRKFAQQLCTALLFLATPEMNIIHCDLKP 745
Query: 260 ENLLLGSA--GELKIADFGWSVHAPSSRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGV 317
EN+LL + +KI DFG S R + Y PE++ G +D +D+WSLG
Sbjct: 744 ENILLCNPKRSAIKIVDFGSSCQL-GQRIYQYIQSRFYRSPEVLLGVPYDLAIDMWSLGC 568
Query: 318 LCYEFLVGKPPF 329
+ E G+PP
Sbjct: 567 ILVEMHTGEPPL 532
>02638
Length = 1490
Score = 53.1 bits (126), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 27/104 (25%), Positives = 52/104 (50%), Gaps = 5/104 (4%)
Frame = +1
Query: 289 LCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFT- 347
L GT+ ++ PE++ G + D+WS+G + E +PP+ ++ I ++ +
Sbjct: 16 LLGTIAFMAPEVLRGESYGRACDVWSVGCVMIEMCTCRPPWNSHDISNHLALIFKIASSV 195
Query: 348 ----FPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANS 387
P+ ++ RDL+ R L+ + RP +++L HP T S
Sbjct: 196 DPPPIPENMSPPVRDLMLRCLEQDSDFRPSAKDLLMHPLFTKYS 327
>11185
Length = 473
Score = 52.4 bits (124), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 30/110 (27%), Positives = 48/110 (43%), Gaps = 24/110 (21%)
Frame = +1
Query: 240 LANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFG----------------------W 277
L L Y HS ++ D++P +LL ++G LK ADFG W
Sbjct: 28 LVTGLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQW 207
Query: 278 SVHAPSS--RRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVG 325
++ + ++ G+ Y+ PE+ +G DLW+LG + YE G
Sbjct: 208 NIQSAEEMMKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSG 357
>25019
Length = 730
Score = 52.4 bits (124), Expect = 4e-07, Method: Compositional matrix adjust.
Identities = 25/59 (42%), Positives = 35/59 (59%), Gaps = 2/59 (3%)
Frame = +3
Query: 260 ENLLLGSAGELKIADFGWSVHAPSSRRTT--LCGTLDYLPPEMIEGRMHDEKVDLWSLG 316
EN+LL G +K+ DFG A + R T CGT++Y+ PE++ H + VD WSLG
Sbjct: 261 ENVLLDKDGHVKLTDFGLCKEAITGTRVTHTFCGTIEYMAPEILTRTGHGKAVDWWSLG 437
>29590
Length = 320
Score = 38.9 bits (89), Expect(2) = 1e-06, Method: Composition-based stats.
Identities = 17/41 (41%), Positives = 24/41 (58%)
Frame = +3
Query: 289 LCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPF 329
+ GT DY+ PE+++ + D+WSLGVL Y L PF
Sbjct: 54 IIGTPDYVAPEVLDYEPLSIQTDMWSLGVLSYVMLTACSPF 176
Score = 31.2 bits (69), Expect(2) = 1e-06, Method: Composition-based stats.
Identities = 16/41 (39%), Positives = 24/41 (58%), Gaps = 4/41 (9%)
Frame = +2
Query: 335 QETYKRISRVEFTFPD----FVTEGARDLISRLLKHNPSQR 371
QET+ IS+V+ FPD ++ A+D I +LL +P R
Sbjct: 191 QETFCNISQVKLDFPDDLFSHISPHAKDFIKKLLVKDPRHR 313
>27274
Length = 396
Score = 49.7 bits (117), Expect = 2e-06, Method: Composition-based stats.
Identities = 30/97 (30%), Positives = 45/97 (46%), Gaps = 12/97 (12%)
Frame = -1
Query: 299 EMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEAN------------TYQETYKRISRVEF 346
E++ G+ H VD+WSLG+L +E L G PFE Y + + SR
Sbjct: 375 ELLRGQQHGPTVDMWSLGILLHELLSGHVPFEPERGSRQMARNMMAVYAQIIRGSSRDVC 196
Query: 347 TFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWI 383
T GA D + RL++ ++R ++ HPWI
Sbjct: 195 DGLALSTHGA-DFLRRLVQLEDTKRLTSQQAFSHPWI 88
>31120
Length = 439
Score = 48.9 bits (115), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 33/99 (33%), Positives = 53/99 (53%), Gaps = 6/99 (6%)
Frame = +1
Query: 299 EMIEGRMHDEKV-DLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTF----PDFVT 353
E++ G +D K+ D WSLGV+ + L GK PF+ + + + +++F D V+
Sbjct: 1 EVVCGVPYDPKMADAWSLGVILFIMLNGKMPFDDSNLNKLLEDQRSKKYSFRRKLQDLVS 180
Query: 354 EGARDLISRLLKHNPSQRPMLREVLEHPWI-TANSSKPS 391
AR +S LL+ N + R L EVL W+ T + +PS
Sbjct: 181 PNARSTVSVLLEPNSAMRWDLNEVLNCQWLQTIDEPRPS 297
>37602
Length = 804
Score = 48.5 bits (114), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 32/99 (32%), Positives = 46/99 (46%), Gaps = 3/99 (3%)
Frame = -1
Query: 189 RHPNILRLYGYFHDATR---VYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALS 245
R NI GYF R +++ +EY G++ E + A E L
Sbjct: 354 RIVNIQTFVGYFDSYLRREKLWIAMEYCGGGSMQDIYHVTGPLTEPQIAFVCRETLKGLH 175
Query: 246 YCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSS 284
Y H + +HRDIK N+LL G++K+ADF W V + S
Sbjct: 174 YLHRRGKMHRDIKGANILLTEEGDVKLADF-WRVSSNHS 61
>07833
Length = 1504
Score = 48.1 bits (113), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 45/213 (21%), Positives = 88/213 (41%), Gaps = 21/213 (9%)
Frame = -3
Query: 188 LRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKF--DEQRTATYITELANALS 245
HPN+L + + + LI ++ P G++Y L S D+ ++ + ++A +
Sbjct: 1448 FNHPNVLPVLACCNQPPNLVLISQFMPFGSLYNTLHGESGIVVDQNQSLRFAMDIARGME 1269
Query: 246 YCHSKRVIHRDIKPE--NLLLGS---------AGELKIADFGWSVHAPSSRRTTLCGTLD 294
+ HS ++P N LL S + +AD+ +S H +
Sbjct: 1268 FLHS-------MEPTIPNFLLTSKHVMIDEDLTARINMADYCFSFHEKGKVYSP-----A 1125
Query: 295 YLPPEMIEGRMHD---EKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISR--VEFTFP 349
++ PE ++ R D D+WS +L +E + PF + E +++ + + P
Sbjct: 1124 WMAPEALQRRPDDINTRAADMWSFAILMWELETREVPFAELSSMEVGMKVALEGLRISIP 945
Query: 350 DFVTEGARDLISRLLKHNPSQRP---MLREVLE 379
++ LI + P +RP M+ +LE
Sbjct: 944 PGISLHMSRLIKICMNEEPGKRPRFDMIIPILE 846
>32000
Length = 644
Score = 48.1 bits (113), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 39/148 (26%), Positives = 63/148 (42%), Gaps = 31/148 (20%)
Frame = -1
Query: 267 AGELKIADFGWS--VHAPSSRRTTLCGTLDYLPPEMIEG-RMHDEKVDLWSLGVLCYEFL 323
++KIADFG + P T TL Y PE++ G R + VD+WSLG + E +
Sbjct: 581 TAKMKIADFGLARVFGLPVRTYTHEVITLWYRAPEILLGCRFYSVPVDIWSLGCIFVEMM 402
Query: 324 VGKPPFEANTYQETYKRISRVEFT-----------FPDF-----------------VTEG 355
+ F ++ + RI R T PD+ +++
Sbjct: 401 TRRALFPGDSEIDQLYRIFRTLGTPDEKVWPGVSKLPDYKPTFPKWPLKNLETVVSLSKV 222
Query: 356 ARDLISRLLKHNPSQRPMLREVLEHPWI 383
DL+ R+L +NP++R R + HP+
Sbjct: 221 GLDLLKRMLTYNPNRRISARSAMRHPYF 138
>07291
Length = 833
Score = 47.8 bits (112), Expect = 8e-06, Method: Compositional matrix adjust.
Identities = 25/97 (25%), Positives = 50/97 (51%), Gaps = 6/97 (6%)
Frame = +1
Query: 239 ELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHA-PSSRRTT----LCGTL 293
++A+ ++Y +V+HR++ N ++ G L+++D+G + P S T +
Sbjct: 73 QIADGMAYLQEVKVVHRNLAARNCIVTEDGRLQLSDYGVTGSLFPQSYYTADDSPARDLV 252
Query: 294 DYLPPEMIEGRMHDEKVDLWSLGVLCYEFLV-GKPPF 329
++ PE I+ K D+W+ GV+ +E L G P+
Sbjct: 253 KWMAPETIDNFHFSSKSDVWAFGVVLWELLTRGITPY 363
>01106
Length = 878
Score = 46.6 bits (109), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 46/147 (31%), Positives = 70/147 (47%), Gaps = 15/147 (10%)
Frame = +3
Query: 133 FEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQ--LEKAGVEHQLRREVEIQSHLRH 190
+ + R LG G F V+L + K +ALKV+ AQ E A E +L + V +S +
Sbjct: 324 YHVIRKLGWGHFSTVWLCWDLTCKRFVALKVVKSAQHYTETALDEVKLLKCVR-ESDVAD 500
Query: 191 PNILRLYGYFHD-------ATRVYLILEYAPLGTVYRELQKLSKFDEQRTATY-----IT 238
P + D T V ++ E LG Y L+ + + + Q + I
Sbjct: 501 PARAKCVQLLDDFKISGVNGTHVAMVFEV--LG--YNLLKLIIRSNYQGIPIHNVKLIIR 668
Query: 239 ELANALSYCHSK-RVIHRDIKPENLLL 264
++ LSY H+K R+IH DIKPEN+L+
Sbjct: 669 QVLEGLSYMHAKCRIIHTDIKPENILI 749
>18481
Length = 437
Score = 44.7 bits (104), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 38/119 (31%), Positives = 57/119 (47%), Gaps = 7/119 (5%)
Frame = -1
Query: 167 AQLEKAGVEHQL-RREVEIQSHL-RHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQK 224
++E V+HQL E ++ + RHP + +Y Y + L++E LG EL
Sbjct: 395 VKIEAIDVKHQLLHYEAKVYEQIGRHPGLPTMYHYGTEKHFNALVME--LLGPSLEELFV 222
Query: 225 LSK--FDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLG---SAGELKIADFGWS 278
+ K F + +L + L + H K IHRD+KP+N L+G L I DFG S
Sbjct: 221 ICKRRFTLKTILMVSDQLLSRLEFIHQKCFIHRDLKPDNFLMGLGRHCHRLYIIDFGLS 45
>32957
Length = 645
Score = 44.7 bits (104), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 20/60 (33%), Positives = 32/60 (53%)
Frame = +3
Query: 275 FGWSVHAPSSRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTY 334
F V R T CGT +Y+ PE+ E + + ++VD W LG+L +E L + ++ Y
Sbjct: 3 FALCVEKSGGRTRTFCGTREYMAPEVHERKEYGKEVDWWGLGILLHELLAAQIKKHSSCY 182
>31489
Length = 329
Score = 43.9 bits (102), Expect = 1e-04, Method: Composition-based stats.
Identities = 23/88 (26%), Positives = 43/88 (48%), Gaps = 6/88 (6%)
Frame = +3
Query: 182 VEIQSHLRHPNI------LRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTAT 235
++I H +H NI L+ +HD ++++ + ++R + E+
Sbjct: 3 IKILKHFKHDNIISIREILKPKDSYHDFKDIHVVFDLME-SDLHRIIYSDQPLTEEHIRY 179
Query: 236 YITELANALSYCHSKRVIHRDIKPENLL 263
++ ++ L Y HS V+HRD+KP NLL
Sbjct: 180 FLYQILRGLKYIHSANVVHRDLKPSNLL 263
>16708
Length = 1397
Score = 43.9 bits (102), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 64/266 (24%), Positives = 100/266 (37%), Gaps = 33/266 (12%)
Frame = -1
Query: 139 LGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNIL-RLY 197
LGKG FG VY AR L KA L+ + + H EVE + L +++
Sbjct: 1379 LGKGVFGKVYEAR--------LLSTHEKAALKTSILCHHSLDEVEALGRIEGGFYLAQMF 1224
Query: 198 GY------FHDATRVYLILEYAPLGTVYRELQK----LSKFDEQRTATYITELANALSYC 247
G F + E PL VY + + + + AL +
Sbjct: 1223 GAWVTCLPFPKMNILLHFYEMGPLCNVYAHYKNKEMPIRWSNPAMVCCIAGQXVCALEHI 1044
Query: 248 HSKRVIHRDIKPENLLLGSAGELKIADFG----WSVH-APSSRRTTLCG---TLDYLPPE 299
H V+H D+K +N+L+ + G K+ D+G + V+ AP+ ++ C T PP
Sbjct: 1043 HELGVVHMDVKADNVLVDAHGNCKLTDYGIAQLYKVYPAPTETHSSGCTNKRTFYTRPPA 864
Query: 300 -MIEGRMHDEKVD------------LWSL-GVLCYEFLVGKPPFEANTYQETYKRISRVE 345
M E+ D LW+L G + V +PP + + R E
Sbjct: 863 TMTPSERFSEEGDGIGTDYFRLGQMLWTLTGAVLLHVWVSRPPKLPD-----WCRTPESE 699
Query: 346 FTFPDFVTEGARDLISRLLKHNPSQR 371
+ G D I +L +P+ R
Sbjct: 698 LS-------GMSDFIEKLCHGDPNMR 642
>17253
Length = 483
Score = 43.9 bits (102), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 27/112 (24%), Positives = 53/112 (47%), Gaps = 13/112 (11%)
Frame = -1
Query: 180 REVEIQSHL-RHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQK--------LSKFDE 230
RE+ I L RHPN++ G + +++E+ G + L+K L+
Sbjct: 402 RELSIMRKLPRHPNVVSFMGCCTMSDPALILMEFCCHGDLLSFLRKRRPDRTVFLTSTAN 223
Query: 231 QRTA----TYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS 278
TA ++ +A +++ + +++HRD+ N+L+ K++DFG S
Sbjct: 222 DLTARDFFSFALHVARGMAHVANNKIVHRDVAARNVLISERNVCKVSDFGLS 67
>20640
Length = 1492
Score = 43.5 bits (101), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 38/144 (26%), Positives = 65/144 (45%), Gaps = 5/144 (3%)
Frame = +1
Query: 253 IHRDIKPENLLLGSAGELKIADFGW--SVHAPSSRRTTLCGT--LDYLPPEMIEGRMHDE 308
+HRD+ N L+G +KI+DFG SVH+ R + + ++P E I
Sbjct: 10 VHRDLATRNCLVGHDLVVKISDFGLARSVHSVDYYRGSEHDAIPIRWMPLEAILYNKFST 189
Query: 309 KVDLWSLGVLCYE-FLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHN 367
+ D+WS GV+ +E F P+ T++E + FV EG ++L
Sbjct: 190 QSDVWSFGVVLWEIFAFALQPYYGLTHEEVVR-----------FVKEG------KVLACP 318
Query: 368 PSQRPMLREVLEHPWITANSSKPS 391
P + E+++ W +++PS
Sbjct: 319 ERTPPPMYELMKQCWHRRPATRPS 390
>07836
Length = 1478
Score = 42.7 bits (99), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 49/195 (25%), Positives = 85/195 (43%), Gaps = 31/195 (15%)
Frame = -1
Query: 159 LALKVLFKAQLEKAGVEHQLRREVEIQSH--LRHPNILRLYGY----FHDATRVYLILEY 212
+A+K+ F + E RE E+ LRH NIL T+++LI +Y
Sbjct: 1469 VAVKIFFTTE------EASWFRETELYQTVLLRHENILGFIAADIKGTGSWTQLFLITDY 1308
Query: 213 APLGTVYRELQKLSK-FDEQRTATYITELANALSYCHSK--------RVIHRDIKPENLL 263
G+++ L LS+ D L++ H + + HRDIK +N+L
Sbjct: 1307 HENGSLHDYL--LSRVLDSSEMLALAHSAICGLAHLHIEIFGTRGKPAIAHRDIKSKNIL 1134
Query: 264 LGSAGELKIADFGWSVH----------APSSRRTTLCGTLDYLPPEMIEGRMHD------ 307
+ G IAD G +V AP+ R+ GT Y+ PE++E ++
Sbjct: 1133 VKKNGTCCIADLGLAVRYISESNEVDVAPNPRQ----GTKRYMAPEVLEMLLNVKNFDAF 966
Query: 308 EKVDLWSLGVLCYEF 322
++ D+++ G++ +E
Sbjct: 965 KQADMYAFGLVMWEI 921
>20559
Length = 430
Score = 39.7 bits (91), Expect(2) = 3e-04, Method: Compositional matrix adjust.
Identities = 22/81 (27%), Positives = 45/81 (55%)
Frame = -2
Query: 130 LEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLR 189
++ +E +G+G +G V+ A+ +++ I+ALK + + + GV RE+ + L+
Sbjct: 378 MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRV-RLDDDDEGVPSSALREICLLKELK 202
Query: 190 HPNILRLYGYFHDATRVYLIL 210
H NI+RL+ H ++ L+
Sbjct: 201 HRNIVRLHDVLHSERKLTLVF 139
Score = 21.9 bits (45), Expect(2) = 3e-04, Method: Compositional matrix adjust.
Identities = 7/12 (58%), Positives = 9/12 (75%)
Frame = -1
Query: 244 LSYCHSKRVIHR 255
L +CHS V+HR
Sbjct: 37 LVFCHSNNVLHR 2
>17300
Length = 480
Score = 42.0 bits (97), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 29/98 (29%), Positives = 46/98 (46%), Gaps = 7/98 (7%)
Frame = +1
Query: 253 IHRDIKPENLLLGSAGELKIADFGWSVHAPSSRR----TTLCGTL--DYLPPEMIEGRMH 306
+HRD+ N+L+ K+ADFG S S TT G + + PE I R
Sbjct: 40 VHRDLAARNILVNEILVCKVADFGLSREIESDTTEGAYTTKGGKIPVRWTAPEAIAYRKF 219
Query: 307 DEKVDLWSLGVLCYEFL-VGKPPFEANTYQETYKRISR 343
D+WS GV+ +E + G+ P+ + Q+ K + +
Sbjct: 220 TSASDVWSFGVVMWEVMSYGERPYWNWSNQDVIKAVEK 333
>11404
Length = 563
Score = 40.8 bits (94), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 42/150 (28%), Positives = 71/150 (47%), Gaps = 12/150 (8%)
Frame = +1
Query: 127 QWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKV-------LFKAQLEKAGVEHQLR 179
+WA + +EI +GKG FG V A + +A+K+ L +AQ+E +E R
Sbjct: 130 KWA-DRYEIDSLIGKGSFGQVVKAYDHTDNEQVAIKIIKNKKPFLNQAQIEVKLLEMMNR 306
Query: 180 REVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKF---DEQRTATY 236
+ + + + I+RL +F R +L L + L +L + + F T +
Sbjct: 307 HDTDNKYY-----IVRLKRHF--MFRSHLCLVFELLSYNLYDLLRNTNFRGVSLNLTRKF 465
Query: 237 ITELANALSYCHS--KRVIHRDIKPENLLL 264
+L AL + + +IH D+KPEN+LL
Sbjct: 466 AQQLCTALLFLATPEMSIIHCDLKPENILL 555
>21210
Length = 518
Score = 40.4 bits (93), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 27/106 (25%), Positives = 49/106 (46%), Gaps = 13/106 (12%)
Frame = +3
Query: 291 GTLDYLPPEMIEGRM----HDEKVDLWSLGVLCYEFLVGKPPFE--ANTYQETYKRISRV 344
G Y+ PE I+ R +D + D+WSLG+ E G+ P+ + + + + + V
Sbjct: 6 GCRPYMAPERIDPRASSHGYDVRSDVWSLGITLMELATGRFPYRKWVSIFDQLQQVVRGV 185
Query: 345 EFTFP-------DFVTEGARDLISRLLKHNPSQRPMLREVLEHPWI 383
P DFV + +++ L + QRP ++L HP++
Sbjct: 186 APCLPHDGAFSHDFV-----NFVNKCLTKDEKQRPKYNKLLAHPFV 308
>21418
Length = 831
Score = 39.7 bits (91), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 20/56 (35%), Positives = 32/56 (57%), Gaps = 4/56 (7%)
Frame = +2
Query: 339 KRISRVEFTFPD----FVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKP 390
KRI ++ FPD V++ A+DLI +L +PS+R + +VL + WI + P
Sbjct: 8 KRIRSGQYDFPDPEWTNVSQAAKDLIKGMLNVDPSKRLCIEDVLRNKWIAQYDAVP 175
>20160
Length = 1277
Score = 38.5 bits (88), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 15/33 (45%), Positives = 24/33 (72%)
Frame = +2
Query: 354 EGARDLISRLLKHNPSQRPMLREVLEHPWITAN 386
E A DLI+R + +PS RP+L ++L+H W+T +
Sbjct: 332 EDAADLINRCIALDPSTRPVLADILKHKWMTKD 430
>00638
Length = 1595
Score = 38.1 bits (87), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 15/37 (40%), Positives = 21/37 (56%)
Frame = +2
Query: 223 QKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKP 259
Q F + Y+ EL AL +CHS ++HRD+KP
Sbjct: 392 QLYQTFTDYDIRFYLYELMKALDFCHSMGIMHRDVKP 502
>31789
Length = 676
Score = 36.6 bits (83), Expect = 0.018, Method: Compositional matrix adjust.
Identities = 27/103 (26%), Positives = 45/103 (43%), Gaps = 5/103 (4%)
Frame = +2
Query: 132 DFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHP 191
D EIGR G F VY + + +A L + K + + E E+ L+HP
Sbjct: 335 DVEIGR----GSFKTVYKGLDTELGVAVAWCELQDKKWNKT-ERQRFKEEAEMLKELQHP 499
Query: 192 NILRLYGYFHDATR-----VYLILEYAPLGTVYRELQKLSKFD 229
NI+R + Y+ + + L+ E GT+ L++ K +
Sbjct: 500 NIVRFFDYWEEHNHRNRKVIILVTELMTSGTLKTYLKRFKKIN 628
>36002
Length = 253
Score = 36.2 bits (82), Expect = 0.023, Method: Compositional matrix adjust.
Identities = 21/66 (31%), Positives = 31/66 (46%), Gaps = 5/66 (7%)
Frame = +1
Query: 324 VGKPPFEANTYQET-YKRISRVEFTFPDF----VTEGARDLISRLLKHNPSQRPMLREVL 378
V +P QE + RI + FP ++ A+DLI LL P +R +VL
Sbjct: 16 VAEPGEACQDCQELLFNRIQDGNYFFPSMEWSAISSSAKDLIRHLLVREPRKRYSAADVL 195
Query: 379 EHPWIT 384
+HPW+
Sbjct: 196 KHPWVC 213
>37063
Length = 455
Score = 35.4 bits (80), Expect = 0.043, Method: Compositional matrix adjust.
Identities = 23/77 (29%), Positives = 41/77 (53%), Gaps = 15/77 (19%)
Frame = -2
Query: 257 IKPENLLLGSAGE---LKIADF----GWSVHAPSSRRTTL---CGTLDYLPPEMIEGRM- 305
+KPEN+L E LKI DF G + ++ L G+ +Y+ PE+++ +
Sbjct: 454 LKPENILCEHLDEVVPLKICDFDLASGINCDGDGTKTPELLTPVGSAEYMAPEVVDAWVG 275
Query: 306 ----HDEKVDLWSLGVL 318
+D++ D+WSLG++
Sbjct: 274 ESFSYDKRCDMWSLGII 224
>20655
Length = 1181
Score = 34.7 bits (78), Expect = 0.068, Method: Compositional matrix adjust.
Identities = 17/56 (30%), Positives = 31/56 (55%), Gaps = 4/56 (7%)
Frame = +2
Query: 339 KRISRVEFTFP----DFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKP 390
KRI ++ FP V++ A+DLI +L +P +R +++V+ W+ N+ P
Sbjct: 8 KRIRNGQYEFPKPEWSRVSQDAKDLIRGMLCTDPDKRLNIKQVMASKWVADNTMVP 175
>00394
Length = 548
Score = 34.7 bits (78), Expect = 0.079, Method: Compositional matrix adjust.
Identities = 23/94 (24%), Positives = 43/94 (45%), Gaps = 5/94 (5%)
Frame = -2
Query: 137 RPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRL 196
+ +G+G F VY + + +A L + KA + + E E+ L+HPNI+R
Sbjct: 280 KEIGRGSFKTVYKGLDTELGVAVAWCELQDKKWNKAE-RQRFKEEAEMLKELQHPNIVRF 104
Query: 197 YGYFHDATR-----VYLILEYAPLGTVYRELQKL 225
+ Y+ + + L+ E GT+ L++
Sbjct: 103 FDYWEEHNHRNRKVIILVTELMTSGTLKTYLKRF 2
>18401
Length = 463
Score = 32.7 bits (73), Expect = 0.26, Method: Compositional matrix adjust.
Identities = 16/63 (25%), Positives = 29/63 (46%)
Frame = -3
Query: 287 TTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEF 346
+T+ T Y PE+I D+WS+G + +E G F+ + +E + R+
Sbjct: 458 STIVSTRHYRAPEVILELGWSHPCDVWSVGCIMFELYTGYTLFQTHDNKEHLAMMERILG 279
Query: 347 TFP 349
+ P
Sbjct: 278 SLP 270
>20773
Length = 391
Score = 32.0 bits (71), Expect = 0.48, Method: Compositional matrix adjust.
Identities = 17/54 (31%), Positives = 28/54 (51%)
Frame = -1
Query: 330 EANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWI 383
+ + ++R SR F VT+ +L+ RLL ++PSQR L HP++
Sbjct: 388 SGSCWSGLHRRRSRPVFPHTTVVTQHFYNLVQRLLTYDPSQRLTPDLALSHPFV 227
>21800
Length = 855
Score = 32.0 bits (71), Expect = 0.49, Method: Compositional matrix adjust.
Identities = 17/46 (36%), Positives = 26/46 (56%), Gaps = 5/46 (10%)
Frame = +2
Query: 237 ITELANALSYCHSK-RVIHRDIKPENLLLGSAG----ELKIADFGW 277
I ++ L+Y H+K +IH DIKPEN+L+ +L + F W
Sbjct: 650 IRQVLEGLNYLHAKCNIIHTDIKPENILICVDDNYIRKLAVDAFEW 787
>36481
Length = 806
Score = 32.0 bits (71), Expect = 0.51, Method: Compositional matrix adjust.
Identities = 32/141 (22%), Positives = 65/141 (46%), Gaps = 8/141 (5%)
Frame = +2
Query: 132 DFEIGRPLGKGKFGNVYLAREKQSKFILALKVL--FKAQLEKAGVE-HQLRREVEIQSHL 188
D ++ G+G FG V ++ +ALK++ E A +E + L + E H
Sbjct: 365 DMKLCPHWGEGTFGKVVQCKDLLKGDDIALKIIKNVDKYREAAKLEINVLEKLREKDPHA 544
Query: 189 RHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKF-----DEQRTATYITELANA 243
+H + L + + ++ + + LG + K + + ++ R +Y +L A
Sbjct: 545 KHMCVQMLDWFDYHG---HVCISFHMLGLSVFDFLKDNSYGAYPIEQVRHISY--QLCYA 709
Query: 244 LSYCHSKRVIHRDIKPENLLL 264
+++ H ++ H D+KPEN+L
Sbjct: 710 VNFLHENQLTHTDLKPENILF 772
>19872
Length = 446
Score = 31.6 bits (70), Expect = 0.53, Method: Compositional matrix adjust.
Identities = 14/41 (34%), Positives = 25/41 (60%), Gaps = 4/41 (9%)
Frame = +3
Query: 349 PDFVTEGA----RDLISRLLKHNPSQRPMLREVLEHPWITA 385
PDF + L+ ++L H+P+QRP R++L+ P++ A
Sbjct: 99 PDFTKDADLHNQSALLRQMLSHDPTQRPSSRDLLQSPYLPA 221
>17932
Length = 597
Score = 28.1 bits (61), Expect(2) = 0.76, Method: Compositional matrix adjust.
Identities = 14/31 (45%), Positives = 16/31 (51%), Gaps = 2/31 (6%)
Frame = -2
Query: 313 WSLGVLCYEFLVGKPPF--EANTYQETYKRI 341
WSLGV YE L G PF + + TY I
Sbjct: 593 WSLGVCAYEMLFGCTPFTDDDGSMVATYNNI 501
Score = 21.6 bits (44), Expect(2) = 0.76, Method: Compositional matrix adjust.
Identities = 14/32 (43%), Positives = 20/32 (62%)
Frame = -3
Query: 352 VTEGARDLISRLLKHNPSQRPMLREVLEHPWI 383
V++ ARDLIS+LL S R E+ +HP+
Sbjct: 460 VSKEARDLISQLLSDGKS-RLGWPELQQHPFF 368
>16350
Length = 1108
Score = 29.6 bits (65), Expect = 2.1, Method: Compositional matrix adjust.
Identities = 12/39 (30%), Positives = 23/39 (58%), Gaps = 1/39 (2%)
Frame = +3
Query: 358 DLISRLLKHNPSQRPMLREVLEHPWITANS-SKPSNCQN 395
D ++ +L+ +P QR + L+HPW+ ++ +PS Q
Sbjct: 762 DFLAPMLEFDPEQRATAAQSLQHPWLKLDA*PEPSGSQQ 878
>20513
Length = 405
Score = 29.3 bits (64), Expect = 2.9, Method: Compositional matrix adjust.
Identities = 12/39 (30%), Positives = 23/39 (58%), Gaps = 1/39 (2%)
Frame = -1
Query: 358 DLISRLLKHNPSQRPMLREVLEHPWITANS-SKPSNCQN 395
D ++ +L+ +P QR + L+HPW+ ++ +PS Q
Sbjct: 282 DFLAPMLEFDPEQRATAAQSLQHPWLKLDA*PEPSGSQQ 166
>17644
Length = 463
Score = 27.7 bits (60), Expect = 8.1, Method: Compositional matrix adjust.
Identities = 13/32 (40%), Positives = 19/32 (59%)
Frame = +3
Query: 352 VTEGARDLISRLLKHNPSQRPMLREVLEHPWI 383
VT+ BL+ RLL ++PSQR L HP++
Sbjct: 69 VTQHFYBLVQRLLTYDPSQRLTPDLALSHPFV 164
>18929
Length = 440
Score = 27.7 bits (60), Expect = 9.8, Method: Compositional matrix adjust.
Identities = 11/38 (28%), Positives = 22/38 (57%)
Frame = +1
Query: 348 FPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITA 385
F + ++ + +I R++ +P QRP ++L HP + A
Sbjct: 34 FINTISVELQQVIRRMMSPDPRQRPTANQLLAHPTLAA 147
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000379247 | hsapiens_gene_ensembl |
Serine/threonine-protein kinase 6 (EC 2.7.11.1) (Aurora kinase A)
(Aurora-A) (Serine/threonine kinase 15) (Aurora/IPL1-related kinase 1)
(Aurora-related kinase 1) (hARK1) (Breast-tumor-amplified kinase).
[Source:Uniprot/SWISSPROT;Acc:O14965]
(403 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
21433 184 3e-69
15910 120 8e-28
03240 119 2e-27
01060 117 6e-27
00300 114 8e-26
30755 110 1e-24
18484 110 1e-24
18921 107 7e-24
12721 105 4e-23
14420 101 5e-22
01707 99 3e-21
14126 98 5e-21
09606 97 8e-21
06405 97 9e-21
09007 94 8e-20
13592 93 2e-19
13212 92 3e-19
01392 91 1e-18
01756 87 1e-17
13066 87 1e-17
11780 80 2e-17
04591 86 2e-17
01718 86 3e-17
17975 85 4e-17
31885 84 7e-17
27546 83 2e-16
00486 82 3e-16
21079 82 6e-16
00392 80 1e-15
01966 79 3e-15
19761 76 2e-14
19094 70 6e-14
26560 75 7e-14
29581 72 4e-13
20152 69 3e-12
27405 68 7e-12
26711 66 3e-11
19301 65 5e-11
38560 65 6e-11
14477 64 1e-10
04852 64 1e-10
06358 64 1e-10
04138 64 2e-10
21808 63 2e-10
00715 62 5e-10
14116 61 6e-10
28157 61 8e-10
12672 61 9e-10
07940 61 1e-09
03508 61 1e-09
26009 41 3e-09
12786 59 3e-09
18663 58 7e-09
28638 56 3e-08
02638 53 2e-07
11185 52 3e-07
25019 52 4e-07
29590 39 1e-06
27274 50 2e-06
31120 49 4e-06
37602 49 4e-06
07833 48 6e-06
32000 48 6e-06
07291 48 8e-06
01106 47 2e-05
18481 45 6e-05
32957 45 6e-05
31489 44 1e-04
16708 44 1e-04
17253 44 1e-04
20640 44 1e-04
07836 43 3e-04
20559 40 3e-04
17300 42 4e-04
11404 41 0.001
21210 40 0.001
21418 40 0.002
20160 39 0.006
00638 38 0.006
31789 37 0.018
36002 36 0.023
37063 35 0.043
20655 35 0.068
00394 35 0.079
18401 33 0.26
20773 32 0.48
21800 32 0.49
36481 32 0.51
19872 32 0.53
17932 28 0.76
16350 30 2.1
20513 29 2.9
17644 28 8.1
18929 28 9.8
>21433
Length = 590
Score = 184 bits (467), Expect(2) = 3e-69, Method: Compositional matrix adjust.
Identities = 93/136 (68%), Positives = 107/136 (78%)
Frame = +2
Query: 231 QRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLC 290
+RTA YI +L++AL YCH ++VIHRDIKPENLLLG G+LKIADFGWSVHAPSSRRTT+C
Sbjct: 167 KRTACYIYQLSSALEYCHYRKVIHRDIKPENLLLGLKGDLKIADFGWSVHAPSSRRTTMC 346
Query: 291 GTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPD 350
GTLDYLPPEM+EG+ HDE VDLWSLGVLCYEFLVG PP + + R P
Sbjct: 347 GTLDYLPPEMVEGKTHDENVDLWSLGVLCYEFLVGTPPLRPSPTRPPTPASPRWTSGSPS 526
Query: 351 FVTEGARDLISRLLKH 366
VT GARDLIS+LL+H
Sbjct: 527 IVTPGARDLISKLLRH 574
Score = 95.9 bits (237), Expect(2) = 3e-69, Method: Compositional matrix adjust.
Identities = 44/64 (68%), Positives = 54/64 (84%), Gaps = 1/64 (1%)
Frame = +3
Query: 176 HQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDE-QRTA 234
HQLRRE+EIQSHLRH NILR++GYFHD TRVYLILE+AP G +Y+ELQ+ KFDE ++ A
Sbjct: 3 HQLRREIEIQSHLRHDNILRMFGYFHDKTRVYLILEFAPKGELYKELQRCHKFDENEQHA 182
Query: 235 TYIT 238
Y +
Sbjct: 183 IYTS 194
>15910
Length = 1361
Score = 120 bits (302), Expect = 8e-28, Method: Compositional matrix adjust.
Identities = 61/177 (34%), Positives = 104/177 (58%), Gaps = 8/177 (4%)
Frame = +2
Query: 226 SKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLL---LGSAGELKIADFGWS-VHA 281
++ E+ A I+++ + + Y H+ V+HRD+KPENLL + +LK+ADFG S +
Sbjct: 449 GQYTEKDAARAISDILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLADFGLSRIIE 628
Query: 282 PSSRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRI 341
P + +T+CGT Y PE+++G + VD+WS+GV+ Y L G PF A E Y++I
Sbjct: 629 PEVQMSTVCGTPGYCAPEVLKGDKYTPSVDMWSVGVIAYILLCGYEPFFAENEFEMYRKI 808
Query: 342 SRVEFTFPD----FVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQ 394
+ E+ F + ++E A+D++ +LL +P +R E L PW+ ++K +N +
Sbjct: 809 IKGEYKFDEEYWSEISENAKDVVRKLLVIDPKKRLTATEALRLPWVKGVATKTTNME 979
>03240
Length = 1683
Score = 119 bits (298), Expect = 2e-27, Method: Compositional matrix adjust.
Identities = 86/283 (30%), Positives = 133/283 (46%), Gaps = 52/283 (18%)
Frame = -3
Query: 133 FEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPN 192
FE + LG G FG V L R+ + + A+K L K+ + K ++ E +I + +
Sbjct: 1285 FEKIKTLGVGAFGEVSLCRKNDTGMLYAMKTLRKSDVLKRNQVAHVKAERDILAEADNEW 1106
Query: 193 ILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRV 252
+++LY F D +Y +++Y P G + L ++ DE Y+ EL A+ H
Sbjct: 1105 VVKLYYSFQDHNYLYFVMDYVPGGDLMGLLIRMEILDEPLARFYVAELVQAIESVHRMGF 926
Query: 253 IHRDIKPENLLLGSAGELKIADFG------WS----------VHA--------------- 281
IHRDIKP+N+L+ G +K+ DFG W+ HA
Sbjct: 925 IHRDIKPDNILIDRNGHIKLTDFGLCTGFRWTHNSKYYQRDGTHARQDSMEVKCQLDEQC 746
Query: 282 ------PSSRRT---------TLCGTLDYLPPEMIEGRM--HDEKVDLWSLGVLCYEFLV 324
P RR +L GT +Y+ PE++ R+ + D WS+GV+ +E LV
Sbjct: 745 QCEILKPLERRRKREQRCLAHSLVGTPNYIAPEVL-SRLGGYTSVCDWWSVGVILFEMLV 569
Query: 325 GKPPFEANTYQET-YKRIS---RVEFTFPDFVTEGARDLISRL 363
G PPF ANT ET YK I+ ++ +++ A+DLI RL
Sbjct: 568 GHPPFYANTPAETQYKVINWKDMLKIPRESNLSQPAKDLILRL 440
>01060
Length = 1800
Score = 117 bits (294), Expect = 6e-27, Method: Compositional matrix adjust.
Identities = 83/305 (27%), Positives = 145/305 (47%), Gaps = 36/305 (11%)
Frame = +1
Query: 129 ALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHL 188
AL D + +G+G +G VY R + + LA+K + + + + GV RE+ + L
Sbjct: 67 ALSDLTDFQKIGEGTYGVVYKCRHRATGRKLAMKKI-RLRGSEDGVPSSAIREIAMLREL 243
Query: 189 RHPNILRLYGYFHDATRVYLILEY--APLGTVYRELQKLSKFDEQRTATYITELANALSY 246
RH NI+ L + R++L+ E+ L + + D + +Y+ ++ + +
Sbjct: 244 RHTNIVCLEDVIMEDERLFLVFEFLSMDLKMYIDKFPEGVVLDRRLVKSYVFQIVTGIXF 423
Query: 247 CHSKRVIHRDIKPENLLLGSAGELKIADFGW--SVHAPSSRRTTLCGTLDYLPPEMIEG- 303
CH +R++HRD+KP+NLL+ G +KIADFG + P T TL Y PE++ G
Sbjct: 424 CHQRRIVHRDLKPQNLLINHTGAIKIADFGMARTFALPVRAYTHEVVTLWYRAPEILMGA 603
Query: 304 RMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRV-----EFTFPDF------- 351
+ VD+WS+G + + L+ P F+ ++ + +I R+ E T+P+F
Sbjct: 604 SKYSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKLPAFN 783
Query: 352 -----------------VTEGARDLISRLLKHNPSQRPMLREVLEHPWI--TANSSKPSN 392
+ DLI R LK +P+QR +++L+H + S KP +
Sbjct: 784 GMFPLWKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYFLNVDTSVKPVD 963
Query: 393 CQNKE 397
+ E
Sbjct: 964 VPSPE 978
>00300
Length = 2318
Score = 114 bits (285), Expect = 8e-26, Method: Compositional matrix adjust.
Identities = 74/257 (28%), Positives = 125/257 (48%), Gaps = 10/257 (3%)
Frame = -1
Query: 136 GRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILR 195
G +G+G+FG VY A + ++ALK + K Q ++ E++I ++H N+++
Sbjct: 1643 GNKIGEGQFGKVYTAVNMSTGELMALKEM-KFQPNDLQQLREMCDEIKIFEGIQHENLVK 1467
Query: 196 LYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHR 255
YG + + +EY GT+ E K+ E Y E+ A+++ H ++HR
Sbjct: 1466 YYGVEVHKDEMLMFMEYCDTGTI-EEAAKMG-LPEYLIRRYTREIVLAVNHLHENSIVHR 1293
Query: 256 DIKPENLLLGSAGELKIADFGWSVHAPSSRRT-----TLCGTLDYLPPEMI---EGRMHD 307
DIK N+ L S G +K+ DFG SV S L GT Y+ PE+ + +
Sbjct: 1292 DIKGANIFLTSNGHVKLGDFGCSVKLKSHTTMPGEFHNLVGTTAYMAPEVFTQNDQGGYG 1113
Query: 308 EKVDLWSLGVLCYEFLVGKPPFE--ANTYQETYKRISRVEFTFPDFVTEGARDLISRLLK 365
D+WSLG + E GK P+ N YQ YK + PD ++ + + ++
Sbjct: 1112 RAADIWSLGCVVIEMATGKRPWHDLDNNYQIMYKVGIGHKPAVPDSLSVEGKHFLDLIMC 933
Query: 366 HNPSQRPMLREVLEHPW 382
H+P+QR + ++L+H +
Sbjct: 932 HDPAQRALASQLLDHTF 882
>30755
Length = 1137
Score = 110 bits (275), Expect = 1e-24, Method: Compositional matrix adjust.
Identities = 60/165 (36%), Positives = 91/165 (55%), Gaps = 7/165 (4%)
Frame = +2
Query: 228 FDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRT 287
F E+RT Y E+ +AL Y HS+ +I+RD+K ENLLL G +K+ADFG + RT
Sbjct: 23 FTEERTRFYGAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCKEDITYGRT 202
Query: 288 T--LCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVE 345
T CGT +YL PE+++ + VD W GV+ YE + G+ PF + + I +
Sbjct: 203 TKTFCGTPEYLAPEVLDDNDYGRAVDWWGTGVVMYEMICGRLPFYNRDHDVLFTLILVED 382
Query: 346 FTFPDFVTEGARDLISRLLKHNPSQR-----PMLREVLEHPWITA 385
FP +T+ A+ L+S LL +P R ++E+ HP+ +
Sbjct: 383 VKFPRNITDEAKSLLSGLLAKDPRNRLGGGQDDVKEIQAHPFFAS 517
>18484
Length = 635
Score = 110 bits (275), Expect = 1e-24, Method: Compositional matrix adjust.
Identities = 57/156 (36%), Positives = 89/156 (57%), Gaps = 2/156 (1%)
Frame = +1
Query: 218 VYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGW 277
+YR +Q+ KF E A Y E+A L + H + +I+RD+K +N++L S G +KIADFG
Sbjct: 7 MYR-IQQEGKFKEPVAAFYAAEIAVGLFFLHDQGIIYRDLKLDNVMLDSEGHIKIADFGM 183
Query: 278 SVHAPSSRRTT--LCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQ 335
+ TT CGT DY+ PE++ + + + VD W+ GVL +E L G+PPF+
Sbjct: 184 CKEGMTGDATTRTFCGTPDYIAPEIVLYQPYSKSVDWWAYGVLLFEMLAGQPPFDGEDED 363
Query: 336 ETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQR 371
E + I+ ++P ++ A L LL NP++R
Sbjct: 364 ELFSSITDHNVSYPKAMSREAVSLCKGLLMKNPTKR 471
>18921
Length = 697
Score = 107 bits (268), Expect = 7e-24, Method: Compositional matrix adjust.
Identities = 64/199 (32%), Positives = 109/199 (54%), Gaps = 3/199 (1%)
Frame = +2
Query: 133 FEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPN 192
F+I LG+G +G+V+ + K++ +LA+K Q+ ++ +E+ I
Sbjct: 35 FDILGKLGEGSYGSVFKSLHKETGQVLAIK-----QVPVDTDLQEIIKEISIMQQCDSKY 199
Query: 193 ILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSK-FDEQRTATYITELANALSYCHSKR 251
I++ YG + T +++++EY G+V ++ +K E+ AT + L Y HS+R
Sbjct: 200 IVKYYGSYFKNTDLWIVMEYCGAGSVSDIMRLRNKTLVEREIATILYYTLKGLXYLHSRR 379
Query: 252 VIHRDIKPENLLLGSAGELKIADFGWS--VHAPSSRRTTLCGTLDYLPPEMIEGRMHDEK 309
IHRDIK N+LL + G K+ADFG + + ++R T+ GT ++ PE+I+ +D
Sbjct: 380 KIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTPYWMAPEVIQEIGYDCV 559
Query: 310 VDLWSLGVLCYEFLVGKPP 328
D+WSLG+ E GKPP
Sbjct: 560 ADIWSLGITALEMAEGKPP 616
>12721
Length = 821
Score = 105 bits (261), Expect = 4e-23, Method: Compositional matrix adjust.
Identities = 69/247 (27%), Positives = 123/247 (49%), Gaps = 5/247 (2%)
Frame = +1
Query: 130 LEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLR 189
L+DF +G+G G V +A + + +A+K K L K L EV +
Sbjct: 94 LDDF---MKIGEGSTGIVCIATSRDGR-QMAVK---KMDLRKQQRRELLFNEVVVMRDYH 252
Query: 190 HPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHS 249
HPNI+ +Y + +++++E+ G ++ ++ DE + AT AL++ H+
Sbjct: 253 HPNIVEMYNSYLVNDELWVVMEFME-GGALTDIVTNNRMDEVQIATVCRACLKALAFLHA 429
Query: 250 KRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSS--RRTTLCGTLDYLPPEMIEGRMHD 307
VIHRDIK +++LL G++K+ DFG+ +R +L GT ++ PE+I +
Sbjct: 430 NGVIHRDIKSDSILLSHDGKVKLXDFGFCAQVTQDLQKRKSLVGTPYWMAPEVISRLPYG 609
Query: 308 EKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRV---EFTFPDFVTEGARDLISRLL 364
+VD+WSLG++ E + +PPF + +RI + + ++ + I R+L
Sbjct: 610 PEVDIWSLGIMVMEMIDAEPPFFNEPPLQAMRRIRDMPPPKLRNTHKISPRLQGFIDRML 789
Query: 365 KHNPSQR 371
+P QR
Sbjct: 790 VRDPHQR 810
>14420
Length = 528
Score = 101 bits (252), Expect = 5e-22, Method: Compositional matrix adjust.
Identities = 48/151 (31%), Positives = 87/151 (57%), Gaps = 2/151 (1%)
Frame = +2
Query: 181 EVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITEL 240
E+ + ++PNI+ + +++++E+ G++ + + + DE + A E
Sbjct: 50 EILVMRENQNPNIVNYLDSYLVGEELWVVMEFLAGGSLTDVVTE-TCMDEGQIAAVCREC 226
Query: 241 ANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAP--SSRRTTLCGTLDYLPP 298
AL + H +VIHRDIK +N+LLG G +K+ DFG+ S+R+T+ GT ++ P
Sbjct: 227 LQALEFLHENQVIHRDIKSDNILLGMDGSVKLTDFGFCAQLSPEQSKRSTMVGTPYWMAP 406
Query: 299 EMIEGRMHDEKVDLWSLGVLCYEFLVGKPPF 329
E++ + + VD+WSLGV+C E + G+PP+
Sbjct: 407 EVVTRKQYGPTVDIWSLGVMCIEMIEGEPPY 499
>01707
Length = 757
Score = 99.0 bits (245), Expect = 3e-21, Method: Compositional matrix adjust.
Identities = 58/201 (28%), Positives = 108/201 (53%), Gaps = 4/201 (1%)
Frame = +1
Query: 130 LEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLR 189
+E +E +G+G +G V+ R K++ ++A+K +++ + ++ RE+ + L+
Sbjct: 61 MEKYEKIGKIGEGSYGVVFKCRNKETSQLVAIKKFVESE-DDPLIKKIAMREIRMLKQLK 237
Query: 190 HPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSK-FDEQRTATYITELANALSYCH 248
HPN++RL F R++L+ +Y T+ EL + + E I + A+++CH
Sbjct: 238 HPNLVRLIEVFRRKKRLHLVFDYVD-HTLLNELDRYPRGLPEPMVKRIIYQTLLAVNFCH 414
Query: 249 SKRVIHRDIKPENLLLGSAGELKIADFGWS--VHAPSSRRTTLCGTLDYLPPEMIEGRM- 305
IHRD+KPEN+L+ G++K+ DFG++ + P T T Y PE++ G
Sbjct: 415 QYNTIHRDVKPENILITRQGQVKLCDFGFARILTGPGDEYTDYVATRWYRAPELLVGDTQ 594
Query: 306 HDEKVDLWSLGVLCYEFLVGK 326
+ VD+W++G + E L G+
Sbjct: 595 YGPPVDVWAIGCVFAELLTGQ 657
>14126
Length = 1265
Score = 98.2 bits (243), Expect = 5e-21, Method: Compositional matrix adjust.
Identities = 86/332 (25%), Positives = 146/332 (43%), Gaps = 46/332 (13%)
Frame = +3
Query: 116 SKQKNEESKKRQWALEDFEIGRPLGKGKFGNVYLARE--KQSKFILALKVLFKAQLEKAG 173
S+ + S++R + +E +G G +G VY AR+ Q +F+ ++ E G
Sbjct: 144 SESAAKMSRRRDSTEQKYEEVAVIGNGAYGTVYKARDLRNQGEFVAMKRIRLNNTEE--G 317
Query: 174 VEHQLRREVEIQSHLR---HPNILRLYGYFHDAT-----RVYLILEYA--PLGTVYRELQ 223
+ RE+ + L HPN++RL H+ R+ L+ EY L T Y
Sbjct: 318 MPMMAIREISMLKQLEQYEHPNVVRLLDVSHNTITDREIRLNLVFEYIEHDLAT-YLAKC 494
Query: 224 KLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS-VHAP 282
R + +L N + + HS R++HRD+KP+NLL+ G LK+ADFG + +++
Sbjct: 495 PSPGLGPDRIKDLMLQLLNGVDFLHSNRIVHRDLKPQNLLISKDGRLKLADFGLARIYSF 674
Query: 283 SSRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRIS 342
TT+ TL Y PE++ + VD+WS G + E + F+ ++ + K+I
Sbjct: 675 HMALTTVVVTLWYRSPEVLMQAEYGTSVDIWSCGCIFAELFTRRALFKGSSEFDQLKKIF 854
Query: 343 RV-----EFTFPDFVTEG----------------------ARDLISRLLKHNPSQRPMLR 375
V +P+ V+ A+DL+ ++L +R R
Sbjct: 855 EVIGLPPAGDWPEGVSVHRNSFRPTPPVPLQTLVPEMDPQAKDLMEKMLVFKSGRRISSR 1034
Query: 376 EVLEHPWITAN------SSKPSNCQNKESASK 401
E L HP++ + SS S +N S +
Sbjct: 1035ESLLHPYLRDDLDSIRTSSSLSTSENDSSDGR 1130
>09606
Length = 1300
Score = 97.4 bits (241), Expect = 8e-21, Method: Compositional matrix adjust.
Identities = 66/285 (23%), Positives = 126/285 (44%), Gaps = 34/285 (11%)
Frame = -3
Query: 130 LEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLR 189
+E+F + LGKG+ +Y R K + +A+ + K + ++ V + +
Sbjct: 1118 MENFVLYEELGKGEHSIIYKGRRKGTINFVAIHCIEKCK------RPEVTNTVRMTHDIS 957
Query: 190 HPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHS 249
HPN+++ + ++ + ++L++E G++ L + E + L L Y HS
Sbjct: 956 HPNVVQFHEWYETSNHLWLVVELCTGGSLADILAQDHHLPETSIRDFGIHLVTGLHYIHS 777
Query: 250 KRVIHRDIKPENLLLGSAGELKIADFG----------------------WSVHAPSS--R 285
++ D++P +LL ++G LK ADFG W++ + +
Sbjct: 776 LGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQWNIQSAEEMMK 597
Query: 286 RTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVE 345
+ G+ Y+ PE+ +G DLW+LG + YE G PPF TY T ++ E
Sbjct: 596 QVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSGHPPFLGETYDITKDKVLNKE 417
Query: 346 FTFPDFVTEGAR----------DLISRLLKHNPSQRPMLREVLEH 380
F P +G+R +L+ LL+ + ++R +++H
Sbjct: 416 FPLPK--VKGSRLSAKPSPEFLNLLESLLQKDSTRRLSWASLVKH 288
>06405
Length = 1965
Score = 97.4 bits (241), Expect = 9e-21, Method: Compositional matrix adjust.
Identities = 68/260 (26%), Positives = 118/260 (45%), Gaps = 9/260 (3%)
Frame = +1
Query: 127 QWALEDFEIGRP--LGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEI 184
+W +E EI LG G++G+VY A K+ I+A+K L E + E I
Sbjct: 241 RWEIERTEIAMKHRLGGGQYGDVYEAMWKRYNKIVAVKTL----KEDTMALNDFLEEAAI 408
Query: 185 QSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTA-TYI-TELAN 242
++HPN+++L G Y++ E+ P G + L+ ++ + TA Y+ T++A+
Sbjct: 409 MKEMKHPNLVQLLGVCTREPPFYIVTEFMPHGNLLDYLRSSTREENGPTALMYMATQIAS 588
Query: 243 ALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGT---LDYLPPE 299
++Y +K IHRD+ N L+ + +K+ADFG + T G + + PE
Sbjct: 589 GMAYLETKNFIHRDLAARNCLVADSNMVKVADFGLARLMKDDTYTAHIGAKFPIKWTAPE 768
Query: 300 MIEGRMHDEKVDLWSLGVLCYEFLV-GKPPFEANTYQETYKRISR-VEFTFPDFVTEGAR 357
+ + D+W+ GVL +E G P+ E Y + R P
Sbjct: 769 GLAFNRFSTRSDIWAFGVLLWELATYGMSPYPGVELTEVYHLLERGYRMERPPGTPADVY 948
Query: 358 DLISRLLKHNPSQRPMLREV 377
L+ + + +P RP +E+
Sbjct: 949 ILMLKCWQWDPKDRPTFKEI 1008
>09007
Length = 1440
Score = 94.4 bits (233), Expect = 8e-20, Method: Compositional matrix adjust.
Identities = 71/264 (26%), Positives = 122/264 (46%), Gaps = 20/264 (7%)
Frame = -1
Query: 135 IGRPLGKGKFGNVYLA---REKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHP 191
+ + LG+G FG V A E K +A+K L K ++ K G E +E I L H
Sbjct: 867 LSKSLGQGHFGTVRQAIWTAESGEKVQVAVKCLSKDKIHKDGQE--FLKETAIMQMLDHE 694
Query: 192 NILRLYGYFHD-ATRVYLILEYAPLGTVYRELQKLS---KFDEQRTATYITELANALSYC 247
NI+R+YG D + L+ E AP+ ++ ++++S F R + ++ + +SY
Sbjct: 693 NIVRVYGVVMDNGADIMLVTELAPMRSLLECVKEVSARVDFSVPRLCDFSQQVCDGMSYL 514
Query: 248 HSKRVIHRDIKPENLLLGSAGELKIADFGWSV-------HAPSSRRTTLCGTLDYLPPEM 300
SKR++HRD+ N+LL S ++KI+D G S + S + L + + PE
Sbjct: 513 ESKRLVHRDLAARNILLFSKSKVKISDVGVSGALGAGKEYYQSQQTIHLQNAVAWCAPES 334
Query: 301 IEGRMHDEKVDLWSLGVLCYEFLV-GKPPFEANTYQETYKRIS-----RVEFTFPDFVTE 354
D+W+ GVL +EF G P+ Q+ + + R+E PD +
Sbjct: 333 FRNLCFSSASDVWAFGVLLWEFFTHGFQPWAGLNGQQIMEAVDAPQSQRLE--QPDLCPK 160
Query: 355 GARDLISRLLKHNPSQRPMLREVL 378
++ + + P +RP ++
Sbjct: 159 EYYAVMLKCWEQEPQRRPTFSQLF 88
>13592
Length = 980
Score = 93.2 bits (230), Expect = 2e-19, Method: Compositional matrix adjust.
Identities = 68/270 (25%), Positives = 128/270 (47%), Gaps = 14/270 (5%)
Frame = +2
Query: 139 LGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYG 198
+G+G+FG VY A + ++A+K + E +++ + E++I ++H N++R YG
Sbjct: 8 IGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETRALKN-VAEELKILEGIKHKNLVRYYG 184
Query: 199 YFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIK 258
+ + +E GT+ ++ E + + +L + ++ H ++HRDIK
Sbjct: 185 IEVHREELLIFMELCSEGTLESLVELTGGLPEALSRRFTAQLLSGVAELHKHGIVHRDIK 364
Query: 259 PENL-LLGSAGELKIADFGWSVHAPSSRRTTL-------CGTLDYLPPEMI---EGRMHD 307
N+ L+ + LK+ DFG +V + TT+ GT Y+ PE+ H
Sbjct: 365 TANIFLVDGSNSLKLGDFGSAVKIQA--HTTVPGELQGYVGTQAYMAPEVFTKTNSDGHG 538
Query: 308 EKVDLWSLGVLCYEFLVGKPP---FEANTYQETYKRISRVEFTFPDFVTEGARDLISRLL 364
D+WS+G + E GK P F++N +Q +K + P+ +++ D I L
Sbjct: 539 RLADIWSVGCVVVEMASGKRPWAQFDSN-FQIMFKVGMGEKPQAPESLSQEGHDFIDHCL 715
Query: 365 KHNPSQRPMLREVLEHPWITANSSKPSNCQ 394
+H+P QR E+LE + + + N +
Sbjct: 716 QHDPKQRLSAIELLEQNFCKSGRDEECNSE 805
>13212
Length = 1067
Score = 92.4 bits (228), Expect = 3e-19, Method: Compositional matrix adjust.
Identities = 60/188 (31%), Positives = 96/188 (51%), Gaps = 10/188 (5%)
Frame = -1
Query: 206 VYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLG 265
V+ +L + L ++ +L+K E + E+ AL + H VIHRDIK N+LL
Sbjct: 1049 VFRVLWWGALDSIMVDLEK--PMTEAQICYVCHEMCMALDFLHRHHVIHRDIKAGNVLLT 876
Query: 266 SAGELKIADFGWSVHAPSS--RRTTLCGTLDYLPPEMI-----EGRMHDEKVDLWSLGVL 318
GE+K+ADFG S + +R T GT ++ PE++ + +D K D+WSLGV
Sbjct: 875 IDGEVKLADFGVSAKNTQTQQKRDTFIGTPYWMAPEVVLCETLKDTPYDFKADIWSLGVT 696
Query: 319 CYEFLVGKPPFEANTYQETYKRISRVE---FTFPDFVTEGARDLISRLLKHNPSQRPMLR 375
EF +PP + +I + + P T+ +D I++ L +P+ RP
Sbjct: 695 LIEFAQIEPPNKEMHPMRVLIKIHKSDPPTLEKPKKWTKLFKDFIAKCLVKDPNLRPTAA 516
Query: 376 EVLEHPWI 383
E+LEHP++
Sbjct: 515 ELLEHPFM 492
>01392
Length = 1806
Score = 90.5 bits (223), Expect = 1e-18, Method: Compositional matrix adjust.
Identities = 57/189 (30%), Positives = 90/189 (47%), Gaps = 34/189 (17%)
Frame = -1
Query: 230 EQRTATYITELANALSYCHSKRVIHRDIKPENLL---LGSAGELKIADF----GWSVHAP 282
E+ + + +A AL + HSK + HRD+KPEN+L L +KI DF G S
Sbjct: 1794 EREASLVVRHIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGISCDGD 1615
Query: 283 SSRRTTL---CGTLDYLPPEMIEGRM-----HDEKVDLWSLGVLCYEFLVGKPPFEANTY 334
++ L G+ +Y+ PE+++ + +D++ DLWSLG++ Y L G PPF
Sbjct: 1614 GTKTPELLTPVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILYIMLCGYPPFYGQCG 1435
Query: 335 QET---------------YKRISRVEFTFPD----FVTEGARDLISRLLKHNPSQRPMLR 375
++ + I + FP ++ A+DLI LL P +R
Sbjct: 1434 EDCGWNRGEACHDCQDMLFNSIQDGHYKFPSQEWTSISSSAKDLIRHLLVREPRKRYSAA 1255
Query: 376 EVLEHPWIT 384
+VL+HPWI
Sbjct: 1254 DVLKHPWIC 1228
>01756
Length = 1858
Score = 87.0 bits (214), Expect = 1e-17, Method: Compositional matrix adjust.
Identities = 66/222 (29%), Positives = 106/222 (47%), Gaps = 16/222 (7%)
Frame = -3
Query: 139 LGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYG 198
+G+G FG V+ AR K++K ++A+K + EK G RE++I L H N++ L
Sbjct: 1718 IGQGTFGEVFKARCKKTKQVVAMKKVLMDN-EKEGFPITALREIKILQLLNHENVVDLIE 1542
Query: 199 YFH----DATR----VYLILEYA--PLGTVYRELQKLSKFDEQRTATYITELANALSYCH 248
A R YL+ E+ L + + + E + + +L N L Y H
Sbjct: 1541 ICSTKATSANRYKSMFYLVFEFCEHDLAGLLSNMSVVFNLPEIKEV--MKQLMNGLYYIH 1368
Query: 249 SKRVIHRDIKPENLLLGSAGELKIADFG----WSVHAPS-SRRTTLCGTLDYLPPEMIEG 303
+++HRD+K N+L+ G LK+ADFG +SV+ +R T TL Y PPE++ G
Sbjct: 1367 RNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRPPELLLG 1188
Query: 304 -RMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRV 344
R + +D W G + E P + T Q I+++
Sbjct: 1187 DRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQNQLTLITQL 1062
>13066
Length = 551
Score = 87.0 bits (214), Expect = 1e-17, Method: Compositional matrix adjust.
Identities = 50/164 (30%), Positives = 87/164 (53%), Gaps = 6/164 (3%)
Frame = +3
Query: 159 LALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTV 218
LA K++ K + VE RE+++ + L HP I++++ + ++ + +A G +
Sbjct: 60 LACKIIDKEKAPVDFVEKFFPRELDLLTKLDHPYIIQIHSILQRXPKNFIFMRFAERGDL 239
Query: 219 YRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS 278
+Q++ E++ + ++ AL+Y HS V HRD+K EN+LL S +K+ADFG++
Sbjct: 240 LTYIQEVGFVKEKQAKIWFYQMTTALNYLHSYDVAHRDLKCENILLSSHFNVKLADFGFA 419
Query: 279 VHAPSS-----RRTTLCGTLDYLPPEMIEGRMHDEKV-DLWSLG 316
+ T CG+ Y PE++ G + KV D WSLG
Sbjct: 420 CACITESGEKYMSRTYCGSAAYAAPEIVYGAPYAPKVADAWSLG 551
>11780
Length = 1713
Score = 80.1 bits (196), Expect(2) = 2e-17, Method: Compositional matrix adjust.
Identities = 57/202 (28%), Positives = 100/202 (49%), Gaps = 7/202 (3%)
Frame = +3
Query: 121 EESKKRQW--ALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQL 178
+E K W A +D EIG +GKG FG+VY + V K +K E
Sbjct: 561 QEFKSGGWVIAXQDLEIGEAIGKGDFGDVYKGMYRGQP------VAIKQLKDKDRGEQSF 722
Query: 179 RREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSK--FDEQRTATY 236
+E + + LRH N++RL G T ++L+ E+ G + L+ + ++ +
Sbjct: 723 LQEASVMTSLRHDNLVRLIGVVLGET-IFLVTEFMGKGNLVEYLRSRGRSVITKKDQINF 899
Query: 237 ITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYL 296
T+ A+ Y SKR++HRD+ N+L+ G+ K++DFG + S +T++ + +
Sbjct: 900 ATDTCAAMEYLESKRLVHRDLAARNVLVHDDGKAKVSDFGLAKFGDFS-QTSVKFPIKWT 1076
Query: 297 PPEMI-EGRMHDE--KVDLWSL 315
PE + E ++H + V+LW +
Sbjct: 1077APEALRENKIH*QVRHVELWHI 1142
Score = 26.6 bits (57), Expect(2) = 2e-17, Method: Compositional matrix adjust.
Identities = 16/72 (22%), Positives = 33/72 (45%), Gaps = 2/72 (2%)
Frame = +1
Query: 309 KVDLWSLGVLCYE-FLVGKPPFEANTYQETYKRISR-VEFTFPDFVTEGARDLISRLLKH 366
K D+WS G+L +E + G+ P+ + + R P+ ++ + +
Sbjct: 1114 KSDMWSFGILLWEIYSFGRVPYPRIPLTDVVMHVERGYRMEAPEGCPPEIYSIMKQAWEL 1293
Query: 367 NPSQRPMLREVL 378
+P++RP + VL
Sbjct: 1294 DPNERPTFKSVL 1329
>04591
Length = 1117
Score = 86.3 bits (212), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 60/184 (32%), Positives = 88/184 (47%), Gaps = 12/184 (6%)
Frame = -2
Query: 171 KAGVEHQLRREVEIQSHLRHPNILRLYGYFHD--------ATRVYLILEYAP--LGTVYR 220
K G RE++I L H N+++L H + YLI EY L +
Sbjct: 1101 KEGFPITALREIKILQQLEHENVVQLQEICHTQAGPYNRYKSTFYLIFEYCDYDLAGLLN 922
Query: 221 ELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSV- 279
L+ KF +++L N L Y H+K+++HRDIK N+LL G LK+ADFG S
Sbjct: 921 NLR--VKFSLADKKNLMSQLLNGLFYIHTKQILHRDIKAANILLTRDGVLKLADFGLSRP 748
Query: 280 HAPSSRRTTLCGTLDYLPPEMIEG-RMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETY 338
S R T TL Y PPE++ G R + ++D+W +G + E KP + + Q
Sbjct: 747 WVKSKRLTNRVVTLWYRPPELLLGEREYGPEIDMWGVGCIMAEMWSRKPLMQGRSEQHQL 568
Query: 339 KRIS 342
I+
Sbjct: 567 SLIT 556
>01718
Length = 959
Score = 85.9 bits (211), Expect = 3e-17, Method: Compositional matrix adjust.
Identities = 62/209 (29%), Positives = 99/209 (47%), Gaps = 11/209 (5%)
Frame = +3
Query: 130 LEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLR 189
L+DF I +G G F V+ + + ++ALK+ H + REV++ + L+
Sbjct: 147 LDDF-ICEKIGAGFFSEVFKVTHRITGQVMALKMN-----TMTSNRHNMLREVQLLNRLQ 308
Query: 190 HPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTAT----YITELANALS 245
H NILR G +++ + EY P G + Q L K DE+ T LA L
Sbjct: 309 HANILRFMGVCVHEGQLHALTEYIPSGNLE---QLLEKKDEELPWTQRIQLTLGLARGLD 479
Query: 246 YCHSKRVIHRDIKPENLLL----GSAGELKIADFGWSVHAP---SSRRTTLCGTLDYLPP 298
Y HS R IHRD+ +N+L+ IADFG + P + G+ ++ P
Sbjct: 480 YLHSTRFIHRDLTSKNILIRREDNHGYHAVIADFGLATKIPDPLDKEKLPTVGSPYWMAP 659
Query: 299 EMIEGRMHDEKVDLWSLGVLCYEFLVGKP 327
E++ G ++E+ DL+S+G++ E P
Sbjct: 660 EVLNGHFYNERADLFSVGIIMCEITARIP 746
>17975
Length = 449
Score = 85.1 bits (209), Expect = 4e-17, Method: Compositional matrix adjust.
Identities = 51/137 (37%), Positives = 80/137 (58%), Gaps = 2/137 (1%)
Frame = +3
Query: 144 FGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDA 203
F V LAR + +A+KV+ K +L++ H L +EV ++HPN++RLY
Sbjct: 6 FAVVKLARHVFTGEKVAVKVIDKTKLDEVSRSH-LFQEVRCMKLVQHPNVVRLYEVIDTQ 182
Query: 204 TRVYLILEYAPLGTVYRELQKLSKFDEQRTAT-YITELANALSYCHSKRVIHRDIKPENL 262
T++YLILE G +Y + + S E++ A Y ++ A+SYCH V+HRD+KPEN+
Sbjct: 183 TKLYLILELGDGGDMYDYIMRHSGGLEEKLAKRYFRQIVEAISYCHKLHVVHRDLKPENV 362
Query: 263 LLGSA-GELKIADFGWS 278
+ G +K+ DFG+S
Sbjct: 363 VFFEKPGLVKLTDFGFS 413
>31885
Length = 529
Score = 84.3 bits (207), Expect = 7e-17, Method: Compositional matrix adjust.
Identities = 48/158 (30%), Positives = 81/158 (51%), Gaps = 6/158 (3%)
Frame = -2
Query: 182 VEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELA 241
V++ + L HP ++ L+ F D ++++++ G + +Q+ F E Y+ +LA
Sbjct: 519 VDMLTRLDHPFLVNLWYAFQDEEDLFMVVDLFLGGDLRYHMQQEVSFREDCVKFYLCQLA 340
Query: 242 NALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSR-RTTLCGTLDYLPPEM 300
L Y S++++HRDIKP+N+LL G + DF + T+ GT Y+ PE+
Sbjct: 339 LVLDYLRSQKIVHRDIKPDNILLDEQGHCHVTDFNIATQLEDDELATSTSGTRPYMAPEV 160
Query: 301 I-----EGRMHDEKVDLWSLGVLCYEFLVGKPPFEANT 333
E R + VD WSLGV +E L + PF ++
Sbjct: 159 YGVAINERRGYGFPVDWWSLGVSLFELLKKRRPFSVHS 46
>27546
Length = 426
Score = 82.8 bits (203), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 42/120 (35%), Positives = 70/120 (58%)
Frame = -1
Query: 159 LALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTV 218
LA K++ KA+ V+ RE+EI + L HPNI++++ ++++ + YA G +
Sbjct: 396 LACKIIDKAKAPIDFVKKFFPRELEILTRLDHPNIIQIHSILQRGPKIFIFMRYAEKGDM 217
Query: 219 YRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS 278
++K DE +T + ++A AL Y HS + HRD+K EN+LL +KIADFG++
Sbjct: 216 LSHIKKTGPIDEAQTKVWFFQMAKALQYLHSHDIAHRDLKCENILLSKRLNVKIADFGFA 37
>00486
Length = 797
Score = 82.0 bits (201), Expect = 3e-16, Method: Compositional matrix adjust.
Identities = 35/84 (41%), Positives = 53/84 (63%)
Frame = -2
Query: 288 TLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFT 347
T CGT++Y+ PE++ H + VD WSLG L Y+ L G PPF A ++T +I + +
Sbjct: 781 TFCGTIEYMAPEILTRTGHGKAVDWWSLGALMYDMLTGSPPFTAENRKKTIDKILKGKLN 602
Query: 348 FPDFVTEGARDLISRLLKHNPSQR 371
P ++T AR LI +LL+ NP++R
Sbjct: 601 LPPYLTNEARGLIKKLLRKNPAER 530
>21079
Length = 878
Score = 81.6 bits (200), Expect = 6e-16, Method: Compositional matrix adjust.
Identities = 42/148 (28%), Positives = 79/148 (53%), Gaps = 4/148 (2%)
Frame = +1
Query: 190 HPNILRLYGYFHDATRVYLILEYAPLGTVY-RELQKLSKFDEQRTATYITELANALSYCH 248
HP +L L+ F + L++E+ G ++ R ++ E+ ++ ++ + + Y H
Sbjct: 1 HPKLLMLWDAFEAPRTMVLVMEFVGAGELFERVIRDDFVLTERDCVHFVRQICSGVGYMH 180
Query: 249 SKRVIHRDIKPENLLLGS--AGELKIADFGWS-VHAPSSRRTTLCGTLDYLPPEMIEGRM 305
++ ++H D+KPEN+L S + ++KI DFG + + P L GT +++ PE++
Sbjct: 181 TQSILHLDLKPENVLCVSDNSNQIKIIDFGLARFYKPGDSLQVLFGTPEFIAPEVVNYDE 360
Query: 306 HDEKVDLWSLGVLCYEFLVGKPPFEANT 333
+ D+WS+GV+CY L G P T
Sbjct: 361 INFTTDMWSIGVICYILLSGLSPSRVTT 444
>00392
Length = 668
Score = 80.5 bits (197), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 48/175 (27%), Positives = 91/175 (52%), Gaps = 9/175 (5%)
Frame = +3
Query: 177 QLRREVEIQSHLRHPNILRLYGYFHDATR-----VYLILEYAPLGTVYRELQKLSKFDEQ 231
+ + E E+ L+HPNI+R + Y+ + + L+ E GT+ L++ K + +
Sbjct: 69 RFKEEAEMLKELQHPNIVRFFDYWEEHNHRNRKVIILVTELMTSGTLKTYLKRFKKPNVK 248
Query: 232 RTATYITELANALSYCHSKR--VIHRDIKPENLLL-GSAGELKIADFGWSVHAPSSRRTT 288
+ ++ L + H++ VIHRD+K +N+ + G G +KI D G + S +
Sbjct: 249 ILKNWCRQVLKGLYFLHTRTPPVIHRDLKCDNIFITGPTGSVKIGDLGLATLKNQSFAKS 428
Query: 289 LCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPF-EANTYQETYKRIS 342
+ GT +++ PEM E +DE VD+++ G+ E + P+ E + + YKR++
Sbjct: 429 VIGTPEFMAPEMYEEH-YDEAVDVYAFGMCMLEMASSEYPYSECSNAAQIYKRVT 590
>01966
Length = 1735
Score = 79.0 bits (193), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 42/135 (31%), Positives = 70/135 (51%), Gaps = 4/135 (2%)
Frame = -1
Query: 173 GVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEY--APLGTVYRELQKLSKFDE 230
GV RE+ + LRH NI+ L + R++L+ E+ L + + D
Sbjct: 1588 GVPSSAIREIAMLRELRHTNIVCLEDVIMEDERLFLVFEFLSMDLKMYIDKFPEGVVLDR 1409
Query: 231 QRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGW--SVHAPSSRRTT 288
+ +Y+ ++ +++CH +R++HRD+KP+NLL+ G +KIADFG + P T
Sbjct: 1408 RLVKSYVFQIVTGINFCHQRRIVHRDLKPQNLLINHTGAIKIADFGMARTFALPVRAYTH 1229
Query: 289 LCGTLDYLPPEMIEG 303
TL Y PE++ G
Sbjct: 1228 EVVTLWYRAPEILMG 1184
>19761
Length = 473
Score = 76.3 bits (186), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 40/142 (28%), Positives = 77/142 (54%), Gaps = 4/142 (2%)
Frame = -3
Query: 230 EQRTATYITELANALSYCHSKR--VIHRDIKPENLLLGSAGELKIADFGWS--VHAPSSR 285
E+ ++ + A+AL+Y H+ ++HRD+KP+N+ + G++++ D G + + P+
Sbjct: 426 ERLIVCWLMQTASALNYMHTHTPVILHRDLKPQNIYVTEKGDVRLGDLGLARKLTGPADF 247
Query: 286 RTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVE 345
T+ GT+ YL PE++ + ++ K D+WSLG + Y+ K E + + +
Sbjct: 246 ATSQVGTIMYLSPEILSQQPYNSKSDIWSLGCVFYDITGKKGSDEMGVMFLLVQVMGGRK 67
Query: 346 FTFPDFVTEGARDLISRLLKHN 367
PD ++ RD ISR+L +
Sbjct: 66 LPLPDHYSQEFRDTISRMLTKD 1
>19094
Length = 898
Score = 70.1 bits (170), Expect(2) = 6e-14, Method: Compositional matrix adjust.
Identities = 39/103 (37%), Positives = 57/103 (55%), Gaps = 2/103 (1%)
Frame = +1
Query: 230 EQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS--VHAPSSRRT 287
E+ AT + L Y HS+R IHRDIK N+LL + G K+ADFG + + ++R
Sbjct: 55 EREIATILYYTLKGL*YLHSRRKIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRN 234
Query: 288 TLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFE 330
T+ GT ++ PE+I+ +D D+WSLG+ E G E
Sbjct: 235 TVIGTPYWMAPEVIQEIGYDCVADIWSLGITALEMAEGNLHME 363
Score = 24.6 bits (52), Expect(2) = 6e-14, Method: Compositional matrix adjust.
Identities = 12/38 (31%), Positives = 19/38 (50%)
Frame = +3
Query: 346 FTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWI 383
F PD + D +S+ L NP R ++L+H +I
Sbjct: 417 FRQPDKWSTEFIDFVSKCLVKNPENRATAVDLLQHDFI 530
>26560
Length = 398
Score = 74.7 bits (182), Expect = 7e-14, Method: Composition-based stats.
Identities = 40/131 (30%), Positives = 67/131 (51%), Gaps = 1/131 (0%)
Frame = -1
Query: 218 VYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGW 277
++ L + F E+ Y E+ L + HS+ V++RD+KP N+LL G ++I+D G
Sbjct: 395 LHYHLSQHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGL 216
Query: 278 SVHAPSSRRTTLCGTLDYLPPE-MIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQE 336
+ R GT Y+ PE +++G+ +D D +S G + Y+ L G PF + +
Sbjct: 215 ACDFSKKRPHASVGTHGYMAPEVLMKGQSYDSSADWFSFGCMLYKLLKGHSPFR--QHNQ 42
Query: 337 TYKRISRVEFT 347
RI R+ T
Sbjct: 41 GQARIDRMTMT 9
>29581
Length = 1278
Score = 72.0 bits (175), Expect = 4e-13, Method: Compositional matrix adjust.
Identities = 63/235 (26%), Positives = 101/235 (42%), Gaps = 38/235 (16%)
Frame = -2
Query: 187 HLRHPNILRL----YGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELAN 242
+LRH NI++L G D+ ++L++EY + F E + + +L
Sbjct: 1187 NLRHQNIVQLQEVVVGKSLDS--LFLVMEYCEQDLASLLDNMPAPFSESQVKCIVLQLLK 1014
Query: 243 ALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVH--APSSRRTTLCGTLDYLPPEM 300
L Y H +IHRD+K NLL+ G +KIADFG + + P T TL Y PE+
Sbjct: 1013 GLRYLHEAFIIHRDLKVSNLLMTDKGCVKIADFGLARNYGKPQKPMTPKVVTLWYRAPEL 834
Query: 301 IEG-RMHDEKVDLWSLGVLCYEFLVGKPPFEANT-------------------------- 333
+ G + H +D+WS G + E L KP +
Sbjct: 833 LFGSKTHSTAIDMWSAGCILGELLGHKPLMPGRSDLQQIELIMELLGTPNDTIWPGFSQL 654
Query: 334 ---YQETYKR--ISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWI 383
Q T K+ + + TFP +++E L++ L ++P +R + LEH +
Sbjct: 653 PAFEQFTLKKQPYNNLRHTFP-WLSESGIRLLNGLFMYHPQKRATAEDCLEHSYF 492
>20152
Length = 445
Score = 68.9 bits (167), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 32/96 (33%), Positives = 50/96 (52%), Gaps = 1/96 (1%)
Frame = +1
Query: 298 PEMIEGRMHDE-KVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGA 356
PE++ G +D VD+WSLGV+ Y +VG+ PF+ ET I + P ++
Sbjct: 1 PEILLGDSYDAPAVDVWSLGVILYMLVVGEAPFQEANDSETLTMIMDCRYQIPPHISHKC 180
Query: 357 RDLISRLLKHNPSQRPMLREVLEHPWITANSSKPSN 392
+DLI ++L+ P R L +L HPW+ P+
Sbjct: 181 QDLIEKMLQREPVDRASLPHILAHPWLNDGDLTPTT 288
>27405
Length = 532
Score = 67.8 bits (164), Expect = 7e-12, Method: Compositional matrix adjust.
Identities = 47/175 (26%), Positives = 84/175 (48%), Gaps = 5/175 (2%)
Frame = -3
Query: 144 FGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLR----HPNILRLYGY 199
FG VY R+ + + A+K L K +++ G E E + S + P I+ +
Sbjct: 527 FGEVYGCRKADTGKMYAMKCLDKKRIKMKGGETLALNERIMLSLVSTGEGSPFIVCMTYA 348
Query: 200 FHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKP 259
F ++ IL+ G ++ L + F E+ Y E+ L + HS+ V++RD+KP
Sbjct: 347 FQTPEKLCFILDLMNGGDLHYHLSQHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKP 168
Query: 260 ENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPE-MIEGRMHDEKVDLW 313
N+LL G ++I+D G + + GT Y+ PE +++G+ +D D +
Sbjct: 167 ANILLDENGHVRISDLGLACDFSKKKPHASVGTHGYMAPEVLMKGQAYDSSADWF 3
>26711
Length = 405
Score = 65.9 bits (159), Expect = 3e-11, Method: Composition-based stats.
Identities = 39/132 (29%), Positives = 72/132 (54%), Gaps = 8/132 (6%)
Frame = -2
Query: 237 ITELANALSYCHSKRVIHRDIKPENLLLG--SAGELKIADFGWSVHAPSSRRTTLC-GTL 293
+ ++ + L + H++ V+H D+KP NLLL +++ DFG + + T L GT
Sbjct: 398 VKQVLDILQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARKLYPPQETFLNHGTP 219
Query: 294 DYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTF---PD 350
+ PE ++ + D+W +GVL Y L G+ PF+A++ E+ K+ +++F P
Sbjct: 218 GFTSPEALDVKPISTASDVWGVGVLAYILLSGQSPFQADSATESLKKTQTCDWSFDVCPS 39
Query: 351 F--VTEGARDLI 360
F +++ A+D I
Sbjct: 38 FSNMSQDAKDFI 3
>19301
Length = 712
Score = 65.1 bits (157), Expect = 5e-11, Method: Compositional matrix adjust.
Identities = 33/101 (32%), Positives = 56/101 (55%), Gaps = 2/101 (1%)
Frame = +2
Query: 180 REVEIQS--HLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYI 237
+E +I++ L HPNI+ G A +I+EY P G +Y L+ + +
Sbjct: 410 KETDIRNLRKLNHPNIISFKGVCTQAPCYCIIMEYCPYGQLYEVLRDGKEIPPALVLDWS 589
Query: 238 TELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS 278
++A+ ++Y HS ++IHRD+K N+L+ +KI+DFG S
Sbjct: 590 KQIASGMNYLHSHKIIHRDLKSPNVLVAKNDVVKISDFGTS 712
>38560
Length = 479
Score = 64.7 bits (156), Expect = 6e-11, Method: Compositional matrix adjust.
Identities = 33/111 (29%), Positives = 58/111 (52%), Gaps = 1/111 (0%)
Frame = -3
Query: 287 TTLCGTLDYLPPEMIEGRMH-DEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVE 345
TT CG+ Y PE+I G + + D+WS+GVL Y L G PF+ ++ + +
Sbjct: 411 TTCCGSPAYAAPELISGLEYLGSEADIWSMGVLLYALLCGYLPFDDEKXSHL*QKNQKRK 232
Query: 346 FTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQNK 396
P++++E L+ +L+ +PS R +R +L+H W+ + P +K
Sbjct: 231 DEVPEWLSEDTTKLLEGMLQTDPSHRITIRRLLDHHWLNQGFNVPVEWASK 79
>14477
Length = 493
Score = 63.9 bits (154), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 44/142 (30%), Positives = 73/142 (51%), Gaps = 2/142 (1%)
Frame = -1
Query: 139 LGKGKFGNVY--LAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRL 196
LG G FG+V + R + +A+KVL A L+ + V+ +L +E E+ + H +I+RL
Sbjct: 466 LGAGNFGSVMKGVCRLDDREIPVAIKVLKNADLDPS-VQSELIKEAEVMKKMDHMHIVRL 290
Query: 197 YGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRD 256
G T + L+LE A LG + + L K + +++ + Y + + +HRD
Sbjct: 289 IGLCEGET-MMLVLELAKLGPLNKFLPKNKHLPLWNILELMWQVSQGMEYLEANKFVHRD 113
Query: 257 IKPENLLLGSAGELKIADFGWS 278
+ N+LL KI+DFG S
Sbjct: 112 LAARNILLCDEHFAKISDFGMS 47
>04852
Length = 1462
Score = 63.9 bits (154), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 40/151 (26%), Positives = 75/151 (49%), Gaps = 5/151 (3%)
Frame = +1
Query: 235 TYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTL- 293
+Y ++A + + S++ IHRD+ N+L+ LKIADFG S ++ + G L
Sbjct: 337 SYAFQIARGMEFLASRKCIHRDLAARNVLVTEEHVLKIADFGLSRTGDYYKKRS-GGRLP 513
Query: 294 -DYLPPEMIEGRMHDEKVDLWSLGVLCYE-FLVGKPPFEANTYQETYKRISRVEFTF--P 349
++ PE + + K D+WS GV+ +E F +G P+ + +E Y ++ + P
Sbjct: 514 VKWMAPEALFDMRYTTKSDVWSFGVVLWEIFSLGGMPYASIPNEELYSKLLDDAYRMPRP 693
Query: 350 DFVTEGARDLISRLLKHNPSQRPMLREVLEH 380
+ + ++ R + PS RP +++ H
Sbjct: 694 ELASGNLYAIMERCWLNRPSDRPEFSQLVGH 786
>06358
Length = 1517
Score = 63.5 bits (153), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 65/273 (23%), Positives = 121/273 (44%), Gaps = 40/273 (14%)
Frame = +3
Query: 140 GKGKFGNVYLAREKQSK-----FILALKVLFK-AQLEKAGVEHQLRREVEIQSHLRHPNI 193
G G V+ A +K +K F+ K + + ++ ++ + LR V+ + LRHP I
Sbjct: 33 GPGLLWKVFAASKKSTKEEASVFVFEKKSVDRYSRRDREAIVEVLRVGVQQLTKLRHPKI 212
Query: 194 LRLYGYFHD-------------ATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITEL 240
L + + A+ ++ + + + TV +ELQ +D + + ++
Sbjct: 213 LAVINPLEESRETLAFATEPVFASLANVLGDLSSIXTVPKELQDYQLYDVE-IKHGLLQV 389
Query: 241 ANALSYCHSK-RVIHRDIKPENLLLGSAGELKIADFGWSVHA--PSSR---------RTT 288
AL + H+ +++HR++ PE ++L G K+A + + V + P S R+
Sbjct: 390 TEALGFLHNDAKMMHRNVCPEAIMLTKLGSWKLAGYEFCVRSSDPQSTDPSYPFYEWRSD 569
Query: 289 LCGT----LDYLPPEMIEGRMHDEKVDLWSLGVLCYE-FLVGKPPFEAN----TYQETYK 339
+ LD++ PE + D++SLG+L Y F GKP FE N ++ +
Sbjct: 570 IAPVTQPHLDFMAPEYVLTMQCGTGSDMFSLGLLVYSVFAKGKPLFECNGELSAFKSNAE 749
Query: 340 RISRVEFTFPDFVTEGARDLISRLLKHNPSQRP 372
+ + + V E RD + LL P+ RP
Sbjct: 750 ELRHMRVSLLGVVPEDLRDHVKLLLNIEPAVRP 848
>04138
Length = 800
Score = 63.5 bits (153), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 51/177 (28%), Positives = 72/177 (40%), Gaps = 40/177 (22%)
Frame = +1
Query: 244 LSYCHSKRVIHRDIKPENLLLGSAGELKIADFG----WSVHAPS-SRRTTLCGTLDYLPP 298
L Y H +++HRD+K N+L+ G LK+ADFG +SV+ +R T TL Y PP
Sbjct: 52 LYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRPP 231
Query: 299 EMIEG-RMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGAR 357
E++ G R + +D W G + E P + T Q I+++ + V G
Sbjct: 232 ELLLGDRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQNQLTLITQLCGSITPEVWPGVT 411
Query: 358 ----------------------------------DLISRLLKHNPSQRPMLREVLEH 380
DL RLLK +PSQR E L H
Sbjct: 412 QLSMYHQIKGALAAGRKNIIRDRFARILKDPYGLDLFERLLKMDPSQRISADEALNH 582
>21808
Length = 1011
Score = 63.2 bits (152), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 43/166 (25%), Positives = 73/166 (43%), Gaps = 5/166 (3%)
Frame = +1
Query: 181 EVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYI-TE 239
E +I LRHP +++LY +++I E G++ LQ + + I +
Sbjct: 82 EAQIMKKLRHPKLIQLYAVCTQDDPIFIITELMKNGSLLEFLQGKGRVLKLPALIDIGAQ 261
Query: 240 LANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGT---LDYL 296
+A ++Y S+ IHRD+ N+L+ +KIADFG + G + +
Sbjct: 262 IACGMAYLESQNYIHRDLAARNILVSDNNTVKIADFGLARVIKEDEYEARVGARFPIKWT 441
Query: 297 PPEMIEGRMHDEKVDLWSLGVLCYEFLV-GKPPFEANTYQETYKRI 341
PE K D+WS G+L E + G+ P+ T E ++
Sbjct: 442 APEAANYNRFTIKSDVWSFGILLTETVTYGRVPYPGMTNAEVLHQV 579
>00715
Length = 1788
Score = 61.6 bits (148), Expect = 5e-10, Method: Compositional matrix adjust.
Identities = 47/177 (26%), Positives = 76/177 (42%), Gaps = 33/177 (18%)
Frame = +1
Query: 188 LRHPNILRLYGY-----FHDATRVYLILEYAP---LGTVYRELQKLSKFDEQRTATYITE 239
LRH N++ + G F D +L +EY L T+ + Q+ D + +
Sbjct: 97 LRHVNVVSILGATSLHRFEDGA--WLAMEYVGPLNLQTILNDHQQ--DIDSSMRLSLALQ 264
Query: 240 LANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVH------------------- 280
+A L Y HS ++H D+KP N LL +L+IADFG H
Sbjct: 265 MARGLHYLHSINIVHLDLKPANCLLTRDLKLRIADFG-CCHQLTPTGLDMGEREGGMAGN 441
Query: 281 ------APSSRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEA 331
+ + L GTL Y PE+++G + D++SLG+ ++ + P+E
Sbjct: 442 ELELTPVQGAWKNELAGTLAYRAPELLKGLQPSVRSDVYSLGITLWQMCTRQGPYEG 612
>14116
Length = 1017
Score = 61.2 bits (147), Expect = 6e-10, Method: Compositional matrix adjust.
Identities = 56/217 (25%), Positives = 96/217 (44%), Gaps = 24/217 (11%)
Frame = -1
Query: 131 EDFEIGRPLGKGKFGNV---YLAR-EKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQS 186
E +G +GKG FG V +L E++ ++A+K L RE+E+QS
Sbjct: 636 EFLTMGEEIGKGNFGCVKRGFLTLPEQKGDILVAVKTLHNNN----------PREIELQS 487
Query: 187 HLR---------HPNILRLYGY---FHDATRVYL-ILEYAPLGTVYRELQKLSKFDEQRT 233
L+ H N+L L G D V L +++ L T R+ Q +
Sbjct: 486 FLQEALIMKDFHHSNVLTLIGICLNLDDMPLVVLPFMKHGDLLTYIRDDQHQPTIKD--L 313
Query: 234 ATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS-------VHAPSSRR 286
Y ++A + Y + +HRD+ N +L +K+ADFG + ++ +++
Sbjct: 312 IMYGVDIARGMDYLAGLKFVHRDLAARNCMLDEDFHVKVADFGLARDIYEKEYYSSENKK 133
Query: 287 TTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFL 323
L + ++ E +E +D K D+WS GV+ +E L
Sbjct: 132 AKL--PVKWMALESLEKGNYDSKTDVWSYGVVLWELL 28
>28157
Length = 400
Score = 61.2 bits (147), Expect = 8e-10, Method: Compositional matrix adjust.
Identities = 39/104 (37%), Positives = 57/104 (54%), Gaps = 7/104 (6%)
Frame = +3
Query: 180 REVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLS---KFDEQRTATY 236
+E++ S + HPNI+ LYG D V L++EYA G++Y L ++ +
Sbjct: 57 QELKQLSRVSHPNIVCLYGACRDHP-VCLVMEYAEGGSLYNVLHGSGPQPQYTAAHAMNW 233
Query: 237 ITELANALSYCHS---KRVIHRDIKPENLLLGSAG-ELKIADFG 276
+ + A + Y H K +IHRD+KP NLLL G +LKI DFG
Sbjct: 234 LLQCALGVEYLHGMKPKALIHRDLKPPNLLLIQCGTKLKICDFG 365
>12672
Length = 773
Score = 60.8 bits (146), Expect = 9e-10, Method: Compositional matrix adjust.
Identities = 45/161 (27%), Positives = 69/161 (42%), Gaps = 24/161 (14%)
Frame = +3
Query: 241 ANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTT------LCGTLD 294
A+ + Y + +HRDIK N+LL S K+ DF V APS T + GT
Sbjct: 21 ASGIQYLNDNGHVHRDIKTANILLDSEYTAKVGDFATVVSAPSGEGKTVQNASVVIGTAA 200
Query: 295 YLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTY------------------QE 336
YL PE I + K+D +S GV+ E + G A Y +E
Sbjct: 201 YLAPEAIHFDVS-TKLDSYSFGVVLLEVITG---LVAQDYSREERTLSSHIMENVEEPEE 368
Query: 337 TYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREV 377
+ + + T+PD + D+ R L + QRP ++++
Sbjct: 369 IHDFVDQSAGTWPDGAVDKLYDISMRCLNLSKKQRPNVKDI 491
>07940
Length = 1336
Score = 60.8 bits (146), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 36/100 (36%), Positives = 54/100 (54%), Gaps = 5/100 (5%)
Frame = -3
Query: 235 TYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS--VHAPSSRRTTLCGT 292
+Y ++A + Y SK+ IHRD+ N+L+ LKIADFG + + R T G
Sbjct: 335 SYAYQVARGMEYLASKQCIHRDLAARNVLVAEEYVLKIADFGLTRNLQQFDYYRKTTDGR 156
Query: 293 L--DYLPPEMIEGRMHDEKVDLWSLGVLCYE-FLVGKPPF 329
L ++ PE + R + K D+WS GVL +E F +G P+
Sbjct: 155 LPVKWMAPEALFDRKYTSKSDVWSYGVLLWEIFTLGGNPY 36
Score = 34.3 bits (77), Expect = 0.088, Method: Compositional matrix adjust.
Identities = 28/95 (29%), Positives = 49/95 (51%), Gaps = 7/95 (7%)
Frame = -3
Query: 131 EDFEIGRPLGKGKFGNVYLAREKQSKF------ILALKVLFKAQLEKAGVEHQLRREVEI 184
E +G LG+G FG V + E F +A+K+L + ++ ++ L RE+E+
Sbjct: 842 ERLVLGDRLGEGAFGLV-MKGEAMGIFKDNNSVTVAVKMLKEDATDREMMD--LIREMEM 672
Query: 185 QSHL-RHPNILRLYGYFHDATRVYLILEYAPLGTV 218
+ +H NI+ L G +Y+I+E+AP G +
Sbjct: 671 MKVIGKHKNIINLLGCCTQRGALYVIVEFAPHGNL 567
>03508
Length = 1463
Score = 60.8 bits (146), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 31/109 (28%), Positives = 57/109 (52%), Gaps = 3/109 (2%)
Frame = +1
Query: 223 QKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAG-ELKIADFGWS-VH 280
Q F + Y+ EL AL +CHS ++HRD+KP N+++ +L++ D+G + +
Sbjct: 847 QLYQTFTDYDIRFYLYELMKALDFCHSMGIMHRDVKPHNVMIDHENKKLRLIDWGLAEFY 1026
Query: 281 APSSRRTTLCGTLDYLPPE-MIEGRMHDEKVDLWSLGVLCYEFLVGKPP 328
P + + PE +++ +M+D +D+WSLG + + K P
Sbjct: 1027HPGMEYNVRVASRYFKGPELLLDYQMYDYSLDMWSLGCMFASMIFRKEP 1173
>26009
Length = 886
Score = 40.8 bits (94), Expect(2) = 3e-09, Method: Compositional matrix adjust.
Identities = 17/49 (34%), Positives = 30/49 (61%)
Frame = +3
Query: 216 GTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLL 264
GT ++ + + + +L +AL + HSK+++HRDIKPEN+L+
Sbjct: 666 GTCLTPSRRNKACGSREAKSVMKQLVSALDFMHSKQLVHRDIKPENVLI 812
Score = 38.1 bits (87), Expect(2) = 3e-09, Method: Compositional matrix adjust.
Identities = 26/91 (28%), Positives = 47/91 (51%), Gaps = 2/91 (2%)
Frame = +2
Query: 131 EDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLR- 189
E +++ + LG+G +G V LAR + + +ALK+L K+ + + +RE ++ L
Sbjct: 416 EHYDVCKELGRGTYGKVVLARCRHTGTQVALKLLPKSCTKL----REFQREFQLSYFLSP 583
Query: 190 HPNILRLYGY-FHDATRVYLILEYAPLGTVY 219
H NI+ Y F + E+A LG ++
Sbjct: 584 HANIIDTYNVAFQTRSSYVFAQEHAVLGDLF 676
>12786
Length = 460
Score = 58.9 bits (141), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 37/127 (29%), Positives = 54/127 (42%), Gaps = 24/127 (18%)
Frame = -3
Query: 228 FDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRT 287
D Y E+ A+ H++ VIH D+KP N +L AG LK+ DFG + + +
Sbjct: 419 LDRMMIKFYWREMLRAVKALHNEGVIHSDLKPANFML-VAGNLKLIDFGIANTLQQDKTS 243
Query: 288 TL----CGTLDYLPPEMIEGRMHDE--------------------KVDLWSLGVLCYEFL 323
L GT Y+ PE I D + D+WSLG + Y +
Sbjct: 242 VLKDSRVGTPSYMSPEAIMAACDDSADDSMEEDGHRTKPKYKVGVRSDVWSLGCILYNMV 63
Query: 324 VGKPPFE 330
G+ PF+
Sbjct: 62 YGRTPFQ 42
>18663
Length = 600
Score = 57.8 bits (138), Expect = 7e-09, Method: Compositional matrix adjust.
Identities = 32/112 (28%), Positives = 52/112 (46%), Gaps = 15/112 (13%)
Frame = +2
Query: 287 TTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEA---------NTYQET 337
+T CGT +Y+ PE++ G + VD W+LGVL YE L G+ PF+ NT
Sbjct: 2 STFCGTPNYIAPEILRGEDYGFSVDWWALGVLLYEMLAGRSPFDIAGASENPDQNTEDYL 181
Query: 338 YKRISRVEFTFPDFVTEGARDLISRLLKHNPSQR------PMLREVLEHPWI 383
++ I P ++ A ++ L NP+ R +++ HP+
Sbjct: 182 FQVILEKTIRIPRSLSVKAASVLKGFLNKNPADRLGCHRESAFMDIVNHPFF 337
>28638
Length = 1458
Score = 55.8 bits (133), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 41/132 (31%), Positives = 60/132 (45%), Gaps = 5/132 (3%)
Frame = -1
Query: 203 ATRVYLILEYAP-LGTVYRELQKLSKFDEQRTATYITELANALSYCHS--KRVIHRDIKP 259
AT L +P + T Q L T + +L AL + + +IH D+KP
Sbjct: 924 ATTCVWCLSCSPTISTTCYATQTLEGVSLNLTRKFAQQLCTALLFLATPEMNIIHCDLKP 745
Query: 260 ENLLLGSA--GELKIADFGWSVHAPSSRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGV 317
EN+LL + +KI DFG S R + Y PE++ G +D +D+WSLG
Sbjct: 744 ENILLCNPKRSAIKIVDFGSSCQL-GQRIYQYIQSRFYRSPEVLLGVPYDLAIDMWSLGC 568
Query: 318 LCYEFLVGKPPF 329
+ E G+PP
Sbjct: 567 ILVEMHTGEPPL 532
>02638
Length = 1490
Score = 53.1 bits (126), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 27/104 (25%), Positives = 52/104 (50%), Gaps = 5/104 (4%)
Frame = +1
Query: 289 LCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFT- 347
L GT+ ++ PE++ G + D+WS+G + E +PP+ ++ I ++ +
Sbjct: 16 LLGTIAFMAPEVLRGESYGRACDVWSVGCVMIEMCTCRPPWNSHDISNHLALIFKIASSV 195
Query: 348 ----FPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANS 387
P+ ++ RDL+ R L+ + RP +++L HP T S
Sbjct: 196 DPPPIPENMSPPVRDLMLRCLEQDSDFRPSAKDLLMHPLFTKYS 327
>11185
Length = 473
Score = 52.4 bits (124), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 30/110 (27%), Positives = 48/110 (43%), Gaps = 24/110 (21%)
Frame = +1
Query: 240 LANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFG----------------------W 277
L L Y HS ++ D++P +LL ++G LK ADFG W
Sbjct: 28 LVTGLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQW 207
Query: 278 SVHAPSS--RRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVG 325
++ + ++ G+ Y+ PE+ +G DLW+LG + YE G
Sbjct: 208 NIQSAEEMMKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSG 357
>25019
Length = 730
Score = 52.4 bits (124), Expect = 4e-07, Method: Compositional matrix adjust.
Identities = 25/59 (42%), Positives = 35/59 (59%), Gaps = 2/59 (3%)
Frame = +3
Query: 260 ENLLLGSAGELKIADFGWSVHAPSSRRTT--LCGTLDYLPPEMIEGRMHDEKVDLWSLG 316
EN+LL G +K+ DFG A + R T CGT++Y+ PE++ H + VD WSLG
Sbjct: 261 ENVLLDKDGHVKLTDFGLCKEAITGTRVTHTFCGTIEYMAPEILTRTGHGKAVDWWSLG 437
>29590
Length = 320
Score = 38.9 bits (89), Expect(2) = 1e-06, Method: Composition-based stats.
Identities = 17/41 (41%), Positives = 24/41 (58%)
Frame = +3
Query: 289 LCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPF 329
+ GT DY+ PE+++ + D+WSLGVL Y L PF
Sbjct: 54 IIGTPDYVAPEVLDYEPLSIQTDMWSLGVLSYVMLTACSPF 176
Score = 31.2 bits (69), Expect(2) = 1e-06, Method: Composition-based stats.
Identities = 16/41 (39%), Positives = 24/41 (58%), Gaps = 4/41 (9%)
Frame = +2
Query: 335 QETYKRISRVEFTFPD----FVTEGARDLISRLLKHNPSQR 371
QET+ IS+V+ FPD ++ A+D I +LL +P R
Sbjct: 191 QETFCNISQVKLDFPDDLFSHISPHAKDFIKKLLVKDPRHR 313
>27274
Length = 396
Score = 49.7 bits (117), Expect = 2e-06, Method: Composition-based stats.
Identities = 30/97 (30%), Positives = 45/97 (46%), Gaps = 12/97 (12%)
Frame = -1
Query: 299 EMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEAN------------TYQETYKRISRVEF 346
E++ G+ H VD+WSLG+L +E L G PFE Y + + SR
Sbjct: 375 ELLRGQQHGPTVDMWSLGILLHELLSGHVPFEPERGSRQMARNMMAVYAQIIRGSSRDVC 196
Query: 347 TFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWI 383
T GA D + RL++ ++R ++ HPWI
Sbjct: 195 DGLALSTHGA-DFLRRLVQLEDTKRLTSQQAFSHPWI 88
>31120
Length = 439
Score = 48.9 bits (115), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 33/99 (33%), Positives = 53/99 (53%), Gaps = 6/99 (6%)
Frame = +1
Query: 299 EMIEGRMHDEKV-DLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTF----PDFVT 353
E++ G +D K+ D WSLGV+ + L GK PF+ + + + +++F D V+
Sbjct: 1 EVVCGVPYDPKMADAWSLGVILFIMLNGKMPFDDSNLNKLLEDQRSKKYSFRRKLQDLVS 180
Query: 354 EGARDLISRLLKHNPSQRPMLREVLEHPWI-TANSSKPS 391
AR +S LL+ N + R L EVL W+ T + +PS
Sbjct: 181 PNARSTVSVLLEPNSAMRWDLNEVLNCQWLQTIDEPRPS 297
>37602
Length = 804
Score = 48.5 bits (114), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 32/99 (32%), Positives = 46/99 (46%), Gaps = 3/99 (3%)
Frame = -1
Query: 189 RHPNILRLYGYFHDATR---VYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALS 245
R NI GYF R +++ +EY G++ E + A E L
Sbjct: 354 RIVNIQTFVGYFDSYLRREKLWIAMEYCGGGSMQDIYHVTGPLTEPQIAFVCRETLKGLH 175
Query: 246 YCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSS 284
Y H + +HRDIK N+LL G++K+ADF W V + S
Sbjct: 174 YLHRRGKMHRDIKGANILLTEEGDVKLADF-WRVSSNHS 61
>07833
Length = 1504
Score = 48.1 bits (113), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 45/213 (21%), Positives = 88/213 (41%), Gaps = 21/213 (9%)
Frame = -3
Query: 188 LRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKF--DEQRTATYITELANALS 245
HPN+L + + + LI ++ P G++Y L S D+ ++ + ++A +
Sbjct: 1448 FNHPNVLPVLACCNQPPNLVLISQFMPFGSLYNTLHGESGIVVDQNQSLRFAMDIARGME 1269
Query: 246 YCHSKRVIHRDIKPE--NLLLGS---------AGELKIADFGWSVHAPSSRRTTLCGTLD 294
+ HS ++P N LL S + +AD+ +S H +
Sbjct: 1268 FLHS-------MEPTIPNFLLTSKHVMIDEDLTARINMADYCFSFHEKGKVYSP-----A 1125
Query: 295 YLPPEMIEGRMHD---EKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISR--VEFTFP 349
++ PE ++ R D D+WS +L +E + PF + E +++ + + P
Sbjct: 1124 WMAPEALQRRPDDINTRAADMWSFAILMWELETREVPFAELSSMEVGMKVALEGLRISIP 945
Query: 350 DFVTEGARDLISRLLKHNPSQRP---MLREVLE 379
++ LI + P +RP M+ +LE
Sbjct: 944 PGISLHMSRLIKICMNEEPGKRPRFDMIIPILE 846
>32000
Length = 644
Score = 48.1 bits (113), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 39/148 (26%), Positives = 63/148 (42%), Gaps = 31/148 (20%)
Frame = -1
Query: 267 AGELKIADFGWS--VHAPSSRRTTLCGTLDYLPPEMIEG-RMHDEKVDLWSLGVLCYEFL 323
++KIADFG + P T TL Y PE++ G R + VD+WSLG + E +
Sbjct: 581 TAKMKIADFGLARVFGLPVRTYTHEVITLWYRAPEILLGCRFYSVPVDIWSLGCIFVEMM 402
Query: 324 VGKPPFEANTYQETYKRISRVEFT-----------FPDF-----------------VTEG 355
+ F ++ + RI R T PD+ +++
Sbjct: 401 TRRALFPGDSEIDQLYRIFRTLGTPDEKVWPGVSKLPDYKPTFPKWPLKNLETVVSLSKV 222
Query: 356 ARDLISRLLKHNPSQRPMLREVLEHPWI 383
DL+ R+L +NP++R R + HP+
Sbjct: 221 GLDLLKRMLTYNPNRRISARSAMRHPYF 138
>07291
Length = 833
Score = 47.8 bits (112), Expect = 8e-06, Method: Compositional matrix adjust.
Identities = 25/97 (25%), Positives = 50/97 (51%), Gaps = 6/97 (6%)
Frame = +1
Query: 239 ELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHA-PSSRRTT----LCGTL 293
++A+ ++Y +V+HR++ N ++ G L+++D+G + P S T +
Sbjct: 73 QIADGMAYLQEVKVVHRNLAARNCIVTEDGRLQLSDYGVTGSLFPQSYYTADDSPARDLV 252
Query: 294 DYLPPEMIEGRMHDEKVDLWSLGVLCYEFLV-GKPPF 329
++ PE I+ K D+W+ GV+ +E L G P+
Sbjct: 253 KWMAPETIDNFHFSSKSDVWAFGVVLWELLTRGITPY 363
>01106
Length = 878
Score = 46.6 bits (109), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 46/147 (31%), Positives = 70/147 (47%), Gaps = 15/147 (10%)
Frame = +3
Query: 133 FEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQ--LEKAGVEHQLRREVEIQSHLRH 190
+ + R LG G F V+L + K +ALKV+ AQ E A E +L + V +S +
Sbjct: 324 YHVIRKLGWGHFSTVWLCWDLTCKRFVALKVVKSAQHYTETALDEVKLLKCVR-ESDVAD 500
Query: 191 PNILRLYGYFHD-------ATRVYLILEYAPLGTVYRELQKLSKFDEQRTATY-----IT 238
P + D T V ++ E LG Y L+ + + + Q + I
Sbjct: 501 PARAKCVQLLDDFKISGVNGTHVAMVFEV--LG--YNLLKLIIRSNYQGIPIHNVKLIIR 668
Query: 239 ELANALSYCHSK-RVIHRDIKPENLLL 264
++ LSY H+K R+IH DIKPEN+L+
Sbjct: 669 QVLEGLSYMHAKCRIIHTDIKPENILI 749
>18481
Length = 437
Score = 44.7 bits (104), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 38/119 (31%), Positives = 57/119 (47%), Gaps = 7/119 (5%)
Frame = -1
Query: 167 AQLEKAGVEHQL-RREVEIQSHL-RHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQK 224
++E V+HQL E ++ + RHP + +Y Y + L++E LG EL
Sbjct: 395 VKIEAIDVKHQLLHYEAKVYEQIGRHPGLPTMYHYGTEKHFNALVME--LLGPSLEELFV 222
Query: 225 LSK--FDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLG---SAGELKIADFGWS 278
+ K F + +L + L + H K IHRD+KP+N L+G L I DFG S
Sbjct: 221 ICKRRFTLKTILMVSDQLLSRLEFIHQKCFIHRDLKPDNFLMGLGRHCHRLYIIDFGLS 45
>32957
Length = 645
Score = 44.7 bits (104), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 20/60 (33%), Positives = 32/60 (53%)
Frame = +3
Query: 275 FGWSVHAPSSRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTY 334
F V R T CGT +Y+ PE+ E + + ++VD W LG+L +E L + ++ Y
Sbjct: 3 FALCVEKSGGRTRTFCGTREYMAPEVHERKEYGKEVDWWGLGILLHELLAAQIKKHSSCY 182
>31489
Length = 329
Score = 43.9 bits (102), Expect = 1e-04, Method: Composition-based stats.
Identities = 23/88 (26%), Positives = 43/88 (48%), Gaps = 6/88 (6%)
Frame = +3
Query: 182 VEIQSHLRHPNI------LRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTAT 235
++I H +H NI L+ +HD ++++ + ++R + E+
Sbjct: 3 IKILKHFKHDNIISIREILKPKDSYHDFKDIHVVFDLME-SDLHRIIYSDQPLTEEHIRY 179
Query: 236 YITELANALSYCHSKRVIHRDIKPENLL 263
++ ++ L Y HS V+HRD+KP NLL
Sbjct: 180 FLYQILRGLKYIHSANVVHRDLKPSNLL 263
>16708
Length = 1397
Score = 43.9 bits (102), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 64/266 (24%), Positives = 100/266 (37%), Gaps = 33/266 (12%)
Frame = -1
Query: 139 LGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNIL-RLY 197
LGKG FG VY AR L KA L+ + + H EVE + L +++
Sbjct: 1379 LGKGVFGKVYEAR--------LLSTHEKAALKTSILCHHSLDEVEALGRIEGGFYLAQMF 1224
Query: 198 GY------FHDATRVYLILEYAPLGTVYRELQK----LSKFDEQRTATYITELANALSYC 247
G F + E PL VY + + + + AL +
Sbjct: 1223 GAWVTCLPFPKMNILLHFYEMGPLCNVYAHYKNKEMPIRWSNPAMVCCIAGQXVCALEHI 1044
Query: 248 HSKRVIHRDIKPENLLLGSAGELKIADFG----WSVH-APSSRRTTLCG---TLDYLPPE 299
H V+H D+K +N+L+ + G K+ D+G + V+ AP+ ++ C T PP
Sbjct: 1043 HELGVVHMDVKADNVLVDAHGNCKLTDYGIAQLYKVYPAPTETHSSGCTNKRTFYTRPPA 864
Query: 300 -MIEGRMHDEKVD------------LWSL-GVLCYEFLVGKPPFEANTYQETYKRISRVE 345
M E+ D LW+L G + V +PP + + R E
Sbjct: 863 TMTPSERFSEEGDGIGTDYFRLGQMLWTLTGAVLLHVWVSRPPKLPD-----WCRTPESE 699
Query: 346 FTFPDFVTEGARDLISRLLKHNPSQR 371
+ G D I +L +P+ R
Sbjct: 698 LS-------GMSDFIEKLCHGDPNMR 642
>17253
Length = 483
Score = 43.9 bits (102), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 27/112 (24%), Positives = 53/112 (47%), Gaps = 13/112 (11%)
Frame = -1
Query: 180 REVEIQSHL-RHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQK--------LSKFDE 230
RE+ I L RHPN++ G + +++E+ G + L+K L+
Sbjct: 402 RELSIMRKLPRHPNVVSFMGCCTMSDPALILMEFCCHGDLLSFLRKRRPDRTVFLTSTAN 223
Query: 231 QRTA----TYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS 278
TA ++ +A +++ + +++HRD+ N+L+ K++DFG S
Sbjct: 222 DLTARDFFSFALHVARGMAHVANNKIVHRDVAARNVLISERNVCKVSDFGLS 67
>20640
Length = 1492
Score = 43.5 bits (101), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 38/144 (26%), Positives = 65/144 (45%), Gaps = 5/144 (3%)
Frame = +1
Query: 253 IHRDIKPENLLLGSAGELKIADFGW--SVHAPSSRRTTLCGT--LDYLPPEMIEGRMHDE 308
+HRD+ N L+G +KI+DFG SVH+ R + + ++P E I
Sbjct: 10 VHRDLATRNCLVGHDLVVKISDFGLARSVHSVDYYRGSEHDAIPIRWMPLEAILYNKFST 189
Query: 309 KVDLWSLGVLCYE-FLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHN 367
+ D+WS GV+ +E F P+ T++E + FV EG ++L
Sbjct: 190 QSDVWSFGVVLWEIFAFALQPYYGLTHEEVVR-----------FVKEG------KVLACP 318
Query: 368 PSQRPMLREVLEHPWITANSSKPS 391
P + E+++ W +++PS
Sbjct: 319 ERTPPPMYELMKQCWHRRPATRPS 390
>07836
Length = 1478
Score = 42.7 bits (99), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 49/195 (25%), Positives = 85/195 (43%), Gaps = 31/195 (15%)
Frame = -1
Query: 159 LALKVLFKAQLEKAGVEHQLRREVEIQSH--LRHPNILRLYGY----FHDATRVYLILEY 212
+A+K+ F + E RE E+ LRH NIL T+++LI +Y
Sbjct: 1469 VAVKIFFTTE------EASWFRETELYQTVLLRHENILGFIAADIKGTGSWTQLFLITDY 1308
Query: 213 APLGTVYRELQKLSK-FDEQRTATYITELANALSYCHSK--------RVIHRDIKPENLL 263
G+++ L LS+ D L++ H + + HRDIK +N+L
Sbjct: 1307 HENGSLHDYL--LSRVLDSSEMLALAHSAICGLAHLHIEIFGTRGKPAIAHRDIKSKNIL 1134
Query: 264 LGSAGELKIADFGWSVH----------APSSRRTTLCGTLDYLPPEMIEGRMHD------ 307
+ G IAD G +V AP+ R+ GT Y+ PE++E ++
Sbjct: 1133 VKKNGTCCIADLGLAVRYISESNEVDVAPNPRQ----GTKRYMAPEVLEMLLNVKNFDAF 966
Query: 308 EKVDLWSLGVLCYEF 322
++ D+++ G++ +E
Sbjct: 965 KQADMYAFGLVMWEI 921
>20559
Length = 430
Score = 39.7 bits (91), Expect(2) = 3e-04, Method: Compositional matrix adjust.
Identities = 22/81 (27%), Positives = 45/81 (55%)
Frame = -2
Query: 130 LEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLR 189
++ +E +G+G +G V+ A+ +++ I+ALK + + + GV RE+ + L+
Sbjct: 378 MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRV-RLDDDDEGVPSSALREICLLKELK 202
Query: 190 HPNILRLYGYFHDATRVYLIL 210
H NI+RL+ H ++ L+
Sbjct: 201 HRNIVRLHDVLHSERKLTLVF 139
Score = 21.9 bits (45), Expect(2) = 3e-04, Method: Compositional matrix adjust.
Identities = 7/12 (58%), Positives = 9/12 (75%)
Frame = -1
Query: 244 LSYCHSKRVIHR 255
L +CHS V+HR
Sbjct: 37 LVFCHSNNVLHR 2
>17300
Length = 480
Score = 42.0 bits (97), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 29/98 (29%), Positives = 46/98 (46%), Gaps = 7/98 (7%)
Frame = +1
Query: 253 IHRDIKPENLLLGSAGELKIADFGWSVHAPSSRR----TTLCGTL--DYLPPEMIEGRMH 306
+HRD+ N+L+ K+ADFG S S TT G + + PE I R
Sbjct: 40 VHRDLAARNILVNEILVCKVADFGLSREIESDTTEGAYTTKGGKIPVRWTAPEAIAYRKF 219
Query: 307 DEKVDLWSLGVLCYEFL-VGKPPFEANTYQETYKRISR 343
D+WS GV+ +E + G+ P+ + Q+ K + +
Sbjct: 220 TSASDVWSFGVVMWEVMSYGERPYWNWSNQDVIKAVEK 333
>11404
Length = 563
Score = 40.8 bits (94), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 42/150 (28%), Positives = 71/150 (47%), Gaps = 12/150 (8%)
Frame = +1
Query: 127 QWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKV-------LFKAQLEKAGVEHQLR 179
+WA + +EI +GKG FG V A + +A+K+ L +AQ+E +E R
Sbjct: 130 KWA-DRYEIDSLIGKGSFGQVVKAYDHTDNEQVAIKIIKNKKPFLNQAQIEVKLLEMMNR 306
Query: 180 REVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKF---DEQRTATY 236
+ + + + I+RL +F R +L L + L +L + + F T +
Sbjct: 307 HDTDNKYY-----IVRLKRHF--MFRSHLCLVFELLSYNLYDLLRNTNFRGVSLNLTRKF 465
Query: 237 ITELANALSYCHS--KRVIHRDIKPENLLL 264
+L AL + + +IH D+KPEN+LL
Sbjct: 466 AQQLCTALLFLATPEMSIIHCDLKPENILL 555
>21210
Length = 518
Score = 40.4 bits (93), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 27/106 (25%), Positives = 49/106 (46%), Gaps = 13/106 (12%)
Frame = +3
Query: 291 GTLDYLPPEMIEGRM----HDEKVDLWSLGVLCYEFLVGKPPFE--ANTYQETYKRISRV 344
G Y+ PE I+ R +D + D+WSLG+ E G+ P+ + + + + + V
Sbjct: 6 GCRPYMAPERIDPRASSHGYDVRSDVWSLGITLMELATGRFPYRKWVSIFDQLQQVVRGV 185
Query: 345 EFTFP-------DFVTEGARDLISRLLKHNPSQRPMLREVLEHPWI 383
P DFV + +++ L + QRP ++L HP++
Sbjct: 186 APCLPHDGAFSHDFV-----NFVNKCLTKDEKQRPKYNKLLAHPFV 308
>21418
Length = 831
Score = 39.7 bits (91), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 20/56 (35%), Positives = 32/56 (57%), Gaps = 4/56 (7%)
Frame = +2
Query: 339 KRISRVEFTFPD----FVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKP 390
KRI ++ FPD V++ A+DLI +L +PS+R + +VL + WI + P
Sbjct: 8 KRIRSGQYDFPDPEWTNVSQAAKDLIKGMLNVDPSKRLCIEDVLRNKWIAQYDAVP 175
>20160
Length = 1277
Score = 38.5 bits (88), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 15/33 (45%), Positives = 24/33 (72%)
Frame = +2
Query: 354 EGARDLISRLLKHNPSQRPMLREVLEHPWITAN 386
E A DLI+R + +PS RP+L ++L+H W+T +
Sbjct: 332 EDAADLINRCIALDPSTRPVLADILKHKWMTKD 430
>00638
Length = 1595
Score = 38.1 bits (87), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 15/37 (40%), Positives = 21/37 (56%)
Frame = +2
Query: 223 QKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKP 259
Q F + Y+ EL AL +CHS ++HRD+KP
Sbjct: 392 QLYQTFTDYDIRFYLYELMKALDFCHSMGIMHRDVKP 502
>31789
Length = 676
Score = 36.6 bits (83), Expect = 0.018, Method: Compositional matrix adjust.
Identities = 27/103 (26%), Positives = 45/103 (43%), Gaps = 5/103 (4%)
Frame = +2
Query: 132 DFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHP 191
D EIGR G F VY + + +A L + K + + E E+ L+HP
Sbjct: 335 DVEIGR----GSFKTVYKGLDTELGVAVAWCELQDKKWNKT-ERQRFKEEAEMLKELQHP 499
Query: 192 NILRLYGYFHDATR-----VYLILEYAPLGTVYRELQKLSKFD 229
NI+R + Y+ + + L+ E GT+ L++ K +
Sbjct: 500 NIVRFFDYWEEHNHRNRKVIILVTELMTSGTLKTYLKRFKKIN 628
>36002
Length = 253
Score = 36.2 bits (82), Expect = 0.023, Method: Compositional matrix adjust.
Identities = 21/66 (31%), Positives = 31/66 (46%), Gaps = 5/66 (7%)
Frame = +1
Query: 324 VGKPPFEANTYQET-YKRISRVEFTFPDF----VTEGARDLISRLLKHNPSQRPMLREVL 378
V +P QE + RI + FP ++ A+DLI LL P +R +VL
Sbjct: 16 VAEPGEACQDCQELLFNRIQDGNYFFPSMEWSAISSSAKDLIRHLLVREPRKRYSAADVL 195
Query: 379 EHPWIT 384
+HPW+
Sbjct: 196 KHPWVC 213
>37063
Length = 455
Score = 35.4 bits (80), Expect = 0.043, Method: Compositional matrix adjust.
Identities = 23/77 (29%), Positives = 41/77 (53%), Gaps = 15/77 (19%)
Frame = -2
Query: 257 IKPENLLLGSAGE---LKIADF----GWSVHAPSSRRTTL---CGTLDYLPPEMIEGRM- 305
+KPEN+L E LKI DF G + ++ L G+ +Y+ PE+++ +
Sbjct: 454 LKPENILCEHLDEVVPLKICDFDLASGINCDGDGTKTPELLTPVGSAEYMAPEVVDAWVG 275
Query: 306 ----HDEKVDLWSLGVL 318
+D++ D+WSLG++
Sbjct: 274 ESFSYDKRCDMWSLGII 224
>20655
Length = 1181
Score = 34.7 bits (78), Expect = 0.068, Method: Compositional matrix adjust.
Identities = 17/56 (30%), Positives = 31/56 (55%), Gaps = 4/56 (7%)
Frame = +2
Query: 339 KRISRVEFTFP----DFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKP 390
KRI ++ FP V++ A+DLI +L +P +R +++V+ W+ N+ P
Sbjct: 8 KRIRNGQYEFPKPEWSRVSQDAKDLIRGMLCTDPDKRLNIKQVMASKWVADNTMVP 175
>00394
Length = 548
Score = 34.7 bits (78), Expect = 0.079, Method: Compositional matrix adjust.
Identities = 23/94 (24%), Positives = 43/94 (45%), Gaps = 5/94 (5%)
Frame = -2
Query: 137 RPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRL 196
+ +G+G F VY + + +A L + KA + + E E+ L+HPNI+R
Sbjct: 280 KEIGRGSFKTVYKGLDTELGVAVAWCELQDKKWNKAE-RQRFKEEAEMLKELQHPNIVRF 104
Query: 197 YGYFHDATR-----VYLILEYAPLGTVYRELQKL 225
+ Y+ + + L+ E GT+ L++
Sbjct: 103 FDYWEEHNHRNRKVIILVTELMTSGTLKTYLKRF 2
>18401
Length = 463
Score = 32.7 bits (73), Expect = 0.26, Method: Compositional matrix adjust.
Identities = 16/63 (25%), Positives = 29/63 (46%)
Frame = -3
Query: 287 TTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEF 346
+T+ T Y PE+I D+WS+G + +E G F+ + +E + R+
Sbjct: 458 STIVSTRHYRAPEVILELGWSHPCDVWSVGCIMFELYTGYTLFQTHDNKEHLAMMERILG 279
Query: 347 TFP 349
+ P
Sbjct: 278 SLP 270
>20773
Length = 391
Score = 32.0 bits (71), Expect = 0.48, Method: Compositional matrix adjust.
Identities = 17/54 (31%), Positives = 28/54 (51%)
Frame = -1
Query: 330 EANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWI 383
+ + ++R SR F VT+ +L+ RLL ++PSQR L HP++
Sbjct: 388 SGSCWSGLHRRRSRPVFPHTTVVTQHFYNLVQRLLTYDPSQRLTPDLALSHPFV 227
>21800
Length = 855
Score = 32.0 bits (71), Expect = 0.49, Method: Compositional matrix adjust.
Identities = 17/46 (36%), Positives = 26/46 (56%), Gaps = 5/46 (10%)
Frame = +2
Query: 237 ITELANALSYCHSK-RVIHRDIKPENLLLGSAG----ELKIADFGW 277
I ++ L+Y H+K +IH DIKPEN+L+ +L + F W
Sbjct: 650 IRQVLEGLNYLHAKCNIIHTDIKPENILICVDDNYIRKLAVDAFEW 787
>36481
Length = 806
Score = 32.0 bits (71), Expect = 0.51, Method: Compositional matrix adjust.
Identities = 32/141 (22%), Positives = 65/141 (46%), Gaps = 8/141 (5%)
Frame = +2
Query: 132 DFEIGRPLGKGKFGNVYLAREKQSKFILALKVL--FKAQLEKAGVE-HQLRREVEIQSHL 188
D ++ G+G FG V ++ +ALK++ E A +E + L + E H
Sbjct: 365 DMKLCPHWGEGTFGKVVQCKDLLKGDDIALKIIKNVDKYREAAKLEINVLEKLREKDPHA 544
Query: 189 RHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKF-----DEQRTATYITELANA 243
+H + L + + ++ + + LG + K + + ++ R +Y +L A
Sbjct: 545 KHMCVQMLDWFDYHG---HVCISFHMLGLSVFDFLKDNSYGAYPIEQVRHISY--QLCYA 709
Query: 244 LSYCHSKRVIHRDIKPENLLL 264
+++ H ++ H D+KPEN+L
Sbjct: 710 VNFLHENQLTHTDLKPENILF 772
>19872
Length = 446
Score = 31.6 bits (70), Expect = 0.53, Method: Compositional matrix adjust.
Identities = 14/41 (34%), Positives = 25/41 (60%), Gaps = 4/41 (9%)
Frame = +3
Query: 349 PDFVTEGA----RDLISRLLKHNPSQRPMLREVLEHPWITA 385
PDF + L+ ++L H+P+QRP R++L+ P++ A
Sbjct: 99 PDFTKDADLHNQSALLRQMLSHDPTQRPSSRDLLQSPYLPA 221
>17932
Length = 597
Score = 28.1 bits (61), Expect(2) = 0.76, Method: Compositional matrix adjust.
Identities = 14/31 (45%), Positives = 16/31 (51%), Gaps = 2/31 (6%)
Frame = -2
Query: 313 WSLGVLCYEFLVGKPPF--EANTYQETYKRI 341
WSLGV YE L G PF + + TY I
Sbjct: 593 WSLGVCAYEMLFGCTPFTDDDGSMVATYNNI 501
Score = 21.6 bits (44), Expect(2) = 0.76, Method: Compositional matrix adjust.
Identities = 14/32 (43%), Positives = 20/32 (62%)
Frame = -3
Query: 352 VTEGARDLISRLLKHNPSQRPMLREVLEHPWI 383
V++ ARDLIS+LL S R E+ +HP+
Sbjct: 460 VSKEARDLISQLLSDGKS-RLGWPELQQHPFF 368
>16350
Length = 1108
Score = 29.6 bits (65), Expect = 2.1, Method: Compositional matrix adjust.
Identities = 12/39 (30%), Positives = 23/39 (58%), Gaps = 1/39 (2%)
Frame = +3
Query: 358 DLISRLLKHNPSQRPMLREVLEHPWITANS-SKPSNCQN 395
D ++ +L+ +P QR + L+HPW+ ++ +PS Q
Sbjct: 762 DFLAPMLEFDPEQRATAAQSLQHPWLKLDA*PEPSGSQQ 878
>20513
Length = 405
Score = 29.3 bits (64), Expect = 2.9, Method: Compositional matrix adjust.
Identities = 12/39 (30%), Positives = 23/39 (58%), Gaps = 1/39 (2%)
Frame = -1
Query: 358 DLISRLLKHNPSQRPMLREVLEHPWITANS-SKPSNCQN 395
D ++ +L+ +P QR + L+HPW+ ++ +PS Q
Sbjct: 282 DFLAPMLEFDPEQRATAAQSLQHPWLKLDA*PEPSGSQQ 166
>17644
Length = 463
Score = 27.7 bits (60), Expect = 8.1, Method: Compositional matrix adjust.
Identities = 13/32 (40%), Positives = 19/32 (59%)
Frame = +3
Query: 352 VTEGARDLISRLLKHNPSQRPMLREVLEHPWI 383
VT+ BL+ RLL ++PSQR L HP++
Sbjct: 69 VTQHFYBLVQRLLTYDPSQRLTPDLALSHPFV 164
>18929
Length = 440
Score = 27.7 bits (60), Expect = 9.8, Method: Compositional matrix adjust.
Identities = 11/38 (28%), Positives = 22/38 (57%)
Frame = +1
Query: 348 FPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITA 385
F + ++ + +I R++ +P QRP ++L HP + A
Sbjct: 34 FINTISVELQQVIRRMMSPDPRQRPTANQLLAHPTLAA 147
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000379249 | hsapiens_gene_ensembl |
Serine/threonine-protein kinase 6 (EC 2.7.11.1) (Aurora kinase A)
(Aurora-A) (Serine/threonine kinase 15) (Aurora/IPL1-related kinase 1)
(Aurora-related kinase 1) (hARK1) (Breast-tumor-amplified kinase).
[Source:Uniprot/SWISSPROT;Acc:O14965]
(403 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
21433 184 3e-69
15910 120 8e-28
03240 119 2e-27
01060 117 6e-27
00300 114 8e-26
30755 110 1e-24
18484 110 1e-24
18921 107 7e-24
12721 105 4e-23
14420 101 5e-22
01707 99 3e-21
14126 98 5e-21
09606 97 8e-21
06405 97 9e-21
09007 94 8e-20
13592 93 2e-19
13212 92 3e-19
01392 91 1e-18
01756 87 1e-17
13066 87 1e-17
11780 80 2e-17
04591 86 2e-17
01718 86 3e-17
17975 85 4e-17
31885 84 7e-17
27546 83 2e-16
00486 82 3e-16
21079 82 6e-16
00392 80 1e-15
01966 79 3e-15
19761 76 2e-14
19094 70 6e-14
26560 75 7e-14
29581 72 4e-13
20152 69 3e-12
27405 68 7e-12
26711 66 3e-11
19301 65 5e-11
38560 65 6e-11
14477 64 1e-10
04852 64 1e-10
06358 64 1e-10
04138 64 2e-10
21808 63 2e-10
00715 62 5e-10
14116 61 6e-10
28157 61 8e-10
12672 61 9e-10
07940 61 1e-09
03508 61 1e-09
26009 41 3e-09
12786 59 3e-09
18663 58 7e-09
28638 56 3e-08
02638 53 2e-07
11185 52 3e-07
25019 52 4e-07
29590 39 1e-06
27274 50 2e-06
31120 49 4e-06
37602 49 4e-06
07833 48 6e-06
32000 48 6e-06
07291 48 8e-06
01106 47 2e-05
18481 45 6e-05
32957 45 6e-05
31489 44 1e-04
16708 44 1e-04
17253 44 1e-04
20640 44 1e-04
07836 43 3e-04
20559 40 3e-04
17300 42 4e-04
11404 41 0.001
21210 40 0.001
21418 40 0.002
20160 39 0.006
00638 38 0.006
31789 37 0.018
36002 36 0.023
37063 35 0.043
20655 35 0.068
00394 35 0.079
18401 33 0.26
20773 32 0.48
21800 32 0.49
36481 32 0.51
19872 32 0.53
17932 28 0.76
16350 30 2.1
20513 29 2.9
17644 28 8.1
18929 28 9.8
>21433
Length = 590
Score = 184 bits (467), Expect(2) = 3e-69, Method: Compositional matrix adjust.
Identities = 93/136 (68%), Positives = 107/136 (78%)
Frame = +2
Query: 231 QRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLC 290
+RTA YI +L++AL YCH ++VIHRDIKPENLLLG G+LKIADFGWSVHAPSSRRTT+C
Sbjct: 167 KRTACYIYQLSSALEYCHYRKVIHRDIKPENLLLGLKGDLKIADFGWSVHAPSSRRTTMC 346
Query: 291 GTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPD 350
GTLDYLPPEM+EG+ HDE VDLWSLGVLCYEFLVG PP + + R P
Sbjct: 347 GTLDYLPPEMVEGKTHDENVDLWSLGVLCYEFLVGTPPLRPSPTRPPTPASPRWTSGSPS 526
Query: 351 FVTEGARDLISRLLKH 366
VT GARDLIS+LL+H
Sbjct: 527 IVTPGARDLISKLLRH 574
Score = 95.9 bits (237), Expect(2) = 3e-69, Method: Compositional matrix adjust.
Identities = 44/64 (68%), Positives = 54/64 (84%), Gaps = 1/64 (1%)
Frame = +3
Query: 176 HQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDE-QRTA 234
HQLRRE+EIQSHLRH NILR++GYFHD TRVYLILE+AP G +Y+ELQ+ KFDE ++ A
Sbjct: 3 HQLRREIEIQSHLRHDNILRMFGYFHDKTRVYLILEFAPKGELYKELQRCHKFDENEQHA 182
Query: 235 TYIT 238
Y +
Sbjct: 183 IYTS 194
>15910
Length = 1361
Score = 120 bits (302), Expect = 8e-28, Method: Compositional matrix adjust.
Identities = 61/177 (34%), Positives = 104/177 (58%), Gaps = 8/177 (4%)
Frame = +2
Query: 226 SKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLL---LGSAGELKIADFGWS-VHA 281
++ E+ A I+++ + + Y H+ V+HRD+KPENLL + +LK+ADFG S +
Sbjct: 449 GQYTEKDAARAISDILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLADFGLSRIIE 628
Query: 282 PSSRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRI 341
P + +T+CGT Y PE+++G + VD+WS+GV+ Y L G PF A E Y++I
Sbjct: 629 PEVQMSTVCGTPGYCAPEVLKGDKYTPSVDMWSVGVIAYILLCGYEPFFAENEFEMYRKI 808
Query: 342 SRVEFTFPD----FVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQ 394
+ E+ F + ++E A+D++ +LL +P +R E L PW+ ++K +N +
Sbjct: 809 IKGEYKFDEEYWSEISENAKDVVRKLLVIDPKKRLTATEALRLPWVKGVATKTTNME 979
>03240
Length = 1683
Score = 119 bits (298), Expect = 2e-27, Method: Compositional matrix adjust.
Identities = 86/283 (30%), Positives = 133/283 (46%), Gaps = 52/283 (18%)
Frame = -3
Query: 133 FEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPN 192
FE + LG G FG V L R+ + + A+K L K+ + K ++ E +I + +
Sbjct: 1285 FEKIKTLGVGAFGEVSLCRKNDTGMLYAMKTLRKSDVLKRNQVAHVKAERDILAEADNEW 1106
Query: 193 ILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRV 252
+++LY F D +Y +++Y P G + L ++ DE Y+ EL A+ H
Sbjct: 1105 VVKLYYSFQDHNYLYFVMDYVPGGDLMGLLIRMEILDEPLARFYVAELVQAIESVHRMGF 926
Query: 253 IHRDIKPENLLLGSAGELKIADFG------WS----------VHA--------------- 281
IHRDIKP+N+L+ G +K+ DFG W+ HA
Sbjct: 925 IHRDIKPDNILIDRNGHIKLTDFGLCTGFRWTHNSKYYQRDGTHARQDSMEVKCQLDEQC 746
Query: 282 ------PSSRRT---------TLCGTLDYLPPEMIEGRM--HDEKVDLWSLGVLCYEFLV 324
P RR +L GT +Y+ PE++ R+ + D WS+GV+ +E LV
Sbjct: 745 QCEILKPLERRRKREQRCLAHSLVGTPNYIAPEVL-SRLGGYTSVCDWWSVGVILFEMLV 569
Query: 325 GKPPFEANTYQET-YKRIS---RVEFTFPDFVTEGARDLISRL 363
G PPF ANT ET YK I+ ++ +++ A+DLI RL
Sbjct: 568 GHPPFYANTPAETQYKVINWKDMLKIPRESNLSQPAKDLILRL 440
>01060
Length = 1800
Score = 117 bits (294), Expect = 6e-27, Method: Compositional matrix adjust.
Identities = 83/305 (27%), Positives = 145/305 (47%), Gaps = 36/305 (11%)
Frame = +1
Query: 129 ALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHL 188
AL D + +G+G +G VY R + + LA+K + + + + GV RE+ + L
Sbjct: 67 ALSDLTDFQKIGEGTYGVVYKCRHRATGRKLAMKKI-RLRGSEDGVPSSAIREIAMLREL 243
Query: 189 RHPNILRLYGYFHDATRVYLILEY--APLGTVYRELQKLSKFDEQRTATYITELANALSY 246
RH NI+ L + R++L+ E+ L + + D + +Y+ ++ + +
Sbjct: 244 RHTNIVCLEDVIMEDERLFLVFEFLSMDLKMYIDKFPEGVVLDRRLVKSYVFQIVTGIXF 423
Query: 247 CHSKRVIHRDIKPENLLLGSAGELKIADFGW--SVHAPSSRRTTLCGTLDYLPPEMIEG- 303
CH +R++HRD+KP+NLL+ G +KIADFG + P T TL Y PE++ G
Sbjct: 424 CHQRRIVHRDLKPQNLLINHTGAIKIADFGMARTFALPVRAYTHEVVTLWYRAPEILMGA 603
Query: 304 RMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRV-----EFTFPDF------- 351
+ VD+WS+G + + L+ P F+ ++ + +I R+ E T+P+F
Sbjct: 604 SKYSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKLPAFN 783
Query: 352 -----------------VTEGARDLISRLLKHNPSQRPMLREVLEHPWI--TANSSKPSN 392
+ DLI R LK +P+QR +++L+H + S KP +
Sbjct: 784 GMFPLWKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYFLNVDTSVKPVD 963
Query: 393 CQNKE 397
+ E
Sbjct: 964 VPSPE 978
>00300
Length = 2318
Score = 114 bits (285), Expect = 8e-26, Method: Compositional matrix adjust.
Identities = 74/257 (28%), Positives = 125/257 (48%), Gaps = 10/257 (3%)
Frame = -1
Query: 136 GRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILR 195
G +G+G+FG VY A + ++ALK + K Q ++ E++I ++H N+++
Sbjct: 1643 GNKIGEGQFGKVYTAVNMSTGELMALKEM-KFQPNDLQQLREMCDEIKIFEGIQHENLVK 1467
Query: 196 LYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHR 255
YG + + +EY GT+ E K+ E Y E+ A+++ H ++HR
Sbjct: 1466 YYGVEVHKDEMLMFMEYCDTGTI-EEAAKMG-LPEYLIRRYTREIVLAVNHLHENSIVHR 1293
Query: 256 DIKPENLLLGSAGELKIADFGWSVHAPSSRRT-----TLCGTLDYLPPEMI---EGRMHD 307
DIK N+ L S G +K+ DFG SV S L GT Y+ PE+ + +
Sbjct: 1292 DIKGANIFLTSNGHVKLGDFGCSVKLKSHTTMPGEFHNLVGTTAYMAPEVFTQNDQGGYG 1113
Query: 308 EKVDLWSLGVLCYEFLVGKPPFE--ANTYQETYKRISRVEFTFPDFVTEGARDLISRLLK 365
D+WSLG + E GK P+ N YQ YK + PD ++ + + ++
Sbjct: 1112 RAADIWSLGCVVIEMATGKRPWHDLDNNYQIMYKVGIGHKPAVPDSLSVEGKHFLDLIMC 933
Query: 366 HNPSQRPMLREVLEHPW 382
H+P+QR + ++L+H +
Sbjct: 932 HDPAQRALASQLLDHTF 882
>30755
Length = 1137
Score = 110 bits (275), Expect = 1e-24, Method: Compositional matrix adjust.
Identities = 60/165 (36%), Positives = 91/165 (55%), Gaps = 7/165 (4%)
Frame = +2
Query: 228 FDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRT 287
F E+RT Y E+ +AL Y HS+ +I+RD+K ENLLL G +K+ADFG + RT
Sbjct: 23 FTEERTRFYGAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCKEDITYGRT 202
Query: 288 T--LCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVE 345
T CGT +YL PE+++ + VD W GV+ YE + G+ PF + + I +
Sbjct: 203 TKTFCGTPEYLAPEVLDDNDYGRAVDWWGTGVVMYEMICGRLPFYNRDHDVLFTLILVED 382
Query: 346 FTFPDFVTEGARDLISRLLKHNPSQR-----PMLREVLEHPWITA 385
FP +T+ A+ L+S LL +P R ++E+ HP+ +
Sbjct: 383 VKFPRNITDEAKSLLSGLLAKDPRNRLGGGQDDVKEIQAHPFFAS 517
>18484
Length = 635
Score = 110 bits (275), Expect = 1e-24, Method: Compositional matrix adjust.
Identities = 57/156 (36%), Positives = 89/156 (57%), Gaps = 2/156 (1%)
Frame = +1
Query: 218 VYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGW 277
+YR +Q+ KF E A Y E+A L + H + +I+RD+K +N++L S G +KIADFG
Sbjct: 7 MYR-IQQEGKFKEPVAAFYAAEIAVGLFFLHDQGIIYRDLKLDNVMLDSEGHIKIADFGM 183
Query: 278 SVHAPSSRRTT--LCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQ 335
+ TT CGT DY+ PE++ + + + VD W+ GVL +E L G+PPF+
Sbjct: 184 CKEGMTGDATTRTFCGTPDYIAPEIVLYQPYSKSVDWWAYGVLLFEMLAGQPPFDGEDED 363
Query: 336 ETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQR 371
E + I+ ++P ++ A L LL NP++R
Sbjct: 364 ELFSSITDHNVSYPKAMSREAVSLCKGLLMKNPTKR 471
>18921
Length = 697
Score = 107 bits (268), Expect = 7e-24, Method: Compositional matrix adjust.
Identities = 64/199 (32%), Positives = 109/199 (54%), Gaps = 3/199 (1%)
Frame = +2
Query: 133 FEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPN 192
F+I LG+G +G+V+ + K++ +LA+K Q+ ++ +E+ I
Sbjct: 35 FDILGKLGEGSYGSVFKSLHKETGQVLAIK-----QVPVDTDLQEIIKEISIMQQCDSKY 199
Query: 193 ILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSK-FDEQRTATYITELANALSYCHSKR 251
I++ YG + T +++++EY G+V ++ +K E+ AT + L Y HS+R
Sbjct: 200 IVKYYGSYFKNTDLWIVMEYCGAGSVSDIMRLRNKTLVEREIATILYYTLKGLXYLHSRR 379
Query: 252 VIHRDIKPENLLLGSAGELKIADFGWS--VHAPSSRRTTLCGTLDYLPPEMIEGRMHDEK 309
IHRDIK N+LL + G K+ADFG + + ++R T+ GT ++ PE+I+ +D
Sbjct: 380 KIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTPYWMAPEVIQEIGYDCV 559
Query: 310 VDLWSLGVLCYEFLVGKPP 328
D+WSLG+ E GKPP
Sbjct: 560 ADIWSLGITALEMAEGKPP 616
>12721
Length = 821
Score = 105 bits (261), Expect = 4e-23, Method: Compositional matrix adjust.
Identities = 69/247 (27%), Positives = 123/247 (49%), Gaps = 5/247 (2%)
Frame = +1
Query: 130 LEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLR 189
L+DF +G+G G V +A + + +A+K K L K L EV +
Sbjct: 94 LDDF---MKIGEGSTGIVCIATSRDGR-QMAVK---KMDLRKQQRRELLFNEVVVMRDYH 252
Query: 190 HPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHS 249
HPNI+ +Y + +++++E+ G ++ ++ DE + AT AL++ H+
Sbjct: 253 HPNIVEMYNSYLVNDELWVVMEFME-GGALTDIVTNNRMDEVQIATVCRACLKALAFLHA 429
Query: 250 KRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSS--RRTTLCGTLDYLPPEMIEGRMHD 307
VIHRDIK +++LL G++K+ DFG+ +R +L GT ++ PE+I +
Sbjct: 430 NGVIHRDIKSDSILLSHDGKVKLXDFGFCAQVTQDLQKRKSLVGTPYWMAPEVISRLPYG 609
Query: 308 EKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRV---EFTFPDFVTEGARDLISRLL 364
+VD+WSLG++ E + +PPF + +RI + + ++ + I R+L
Sbjct: 610 PEVDIWSLGIMVMEMIDAEPPFFNEPPLQAMRRIRDMPPPKLRNTHKISPRLQGFIDRML 789
Query: 365 KHNPSQR 371
+P QR
Sbjct: 790 VRDPHQR 810
>14420
Length = 528
Score = 101 bits (252), Expect = 5e-22, Method: Compositional matrix adjust.
Identities = 48/151 (31%), Positives = 87/151 (57%), Gaps = 2/151 (1%)
Frame = +2
Query: 181 EVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITEL 240
E+ + ++PNI+ + +++++E+ G++ + + + DE + A E
Sbjct: 50 EILVMRENQNPNIVNYLDSYLVGEELWVVMEFLAGGSLTDVVTE-TCMDEGQIAAVCREC 226
Query: 241 ANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAP--SSRRTTLCGTLDYLPP 298
AL + H +VIHRDIK +N+LLG G +K+ DFG+ S+R+T+ GT ++ P
Sbjct: 227 LQALEFLHENQVIHRDIKSDNILLGMDGSVKLTDFGFCAQLSPEQSKRSTMVGTPYWMAP 406
Query: 299 EMIEGRMHDEKVDLWSLGVLCYEFLVGKPPF 329
E++ + + VD+WSLGV+C E + G+PP+
Sbjct: 407 EVVTRKQYGPTVDIWSLGVMCIEMIEGEPPY 499
>01707
Length = 757
Score = 99.0 bits (245), Expect = 3e-21, Method: Compositional matrix adjust.
Identities = 58/201 (28%), Positives = 108/201 (53%), Gaps = 4/201 (1%)
Frame = +1
Query: 130 LEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLR 189
+E +E +G+G +G V+ R K++ ++A+K +++ + ++ RE+ + L+
Sbjct: 61 MEKYEKIGKIGEGSYGVVFKCRNKETSQLVAIKKFVESE-DDPLIKKIAMREIRMLKQLK 237
Query: 190 HPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSK-FDEQRTATYITELANALSYCH 248
HPN++RL F R++L+ +Y T+ EL + + E I + A+++CH
Sbjct: 238 HPNLVRLIEVFRRKKRLHLVFDYVD-HTLLNELDRYPRGLPEPMVKRIIYQTLLAVNFCH 414
Query: 249 SKRVIHRDIKPENLLLGSAGELKIADFGWS--VHAPSSRRTTLCGTLDYLPPEMIEGRM- 305
IHRD+KPEN+L+ G++K+ DFG++ + P T T Y PE++ G
Sbjct: 415 QYNTIHRDVKPENILITRQGQVKLCDFGFARILTGPGDEYTDYVATRWYRAPELLVGDTQ 594
Query: 306 HDEKVDLWSLGVLCYEFLVGK 326
+ VD+W++G + E L G+
Sbjct: 595 YGPPVDVWAIGCVFAELLTGQ 657
>14126
Length = 1265
Score = 98.2 bits (243), Expect = 5e-21, Method: Compositional matrix adjust.
Identities = 86/332 (25%), Positives = 146/332 (43%), Gaps = 46/332 (13%)
Frame = +3
Query: 116 SKQKNEESKKRQWALEDFEIGRPLGKGKFGNVYLARE--KQSKFILALKVLFKAQLEKAG 173
S+ + S++R + +E +G G +G VY AR+ Q +F+ ++ E G
Sbjct: 144 SESAAKMSRRRDSTEQKYEEVAVIGNGAYGTVYKARDLRNQGEFVAMKRIRLNNTEE--G 317
Query: 174 VEHQLRREVEIQSHLR---HPNILRLYGYFHDAT-----RVYLILEYA--PLGTVYRELQ 223
+ RE+ + L HPN++RL H+ R+ L+ EY L T Y
Sbjct: 318 MPMMAIREISMLKQLEQYEHPNVVRLLDVSHNTITDREIRLNLVFEYIEHDLAT-YLAKC 494
Query: 224 KLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS-VHAP 282
R + +L N + + HS R++HRD+KP+NLL+ G LK+ADFG + +++
Sbjct: 495 PSPGLGPDRIKDLMLQLLNGVDFLHSNRIVHRDLKPQNLLISKDGRLKLADFGLARIYSF 674
Query: 283 SSRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRIS 342
TT+ TL Y PE++ + VD+WS G + E + F+ ++ + K+I
Sbjct: 675 HMALTTVVVTLWYRSPEVLMQAEYGTSVDIWSCGCIFAELFTRRALFKGSSEFDQLKKIF 854
Query: 343 RV-----EFTFPDFVTEG----------------------ARDLISRLLKHNPSQRPMLR 375
V +P+ V+ A+DL+ ++L +R R
Sbjct: 855 EVIGLPPAGDWPEGVSVHRNSFRPTPPVPLQTLVPEMDPQAKDLMEKMLVFKSGRRISSR 1034
Query: 376 EVLEHPWITAN------SSKPSNCQNKESASK 401
E L HP++ + SS S +N S +
Sbjct: 1035ESLLHPYLRDDLDSIRTSSSLSTSENDSSDGR 1130
>09606
Length = 1300
Score = 97.4 bits (241), Expect = 8e-21, Method: Compositional matrix adjust.
Identities = 66/285 (23%), Positives = 126/285 (44%), Gaps = 34/285 (11%)
Frame = -3
Query: 130 LEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLR 189
+E+F + LGKG+ +Y R K + +A+ + K + ++ V + +
Sbjct: 1118 MENFVLYEELGKGEHSIIYKGRRKGTINFVAIHCIEKCK------RPEVTNTVRMTHDIS 957
Query: 190 HPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHS 249
HPN+++ + ++ + ++L++E G++ L + E + L L Y HS
Sbjct: 956 HPNVVQFHEWYETSNHLWLVVELCTGGSLADILAQDHHLPETSIRDFGIHLVTGLHYIHS 777
Query: 250 KRVIHRDIKPENLLLGSAGELKIADFG----------------------WSVHAPSS--R 285
++ D++P +LL ++G LK ADFG W++ + +
Sbjct: 776 LGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQWNIQSAEEMMK 597
Query: 286 RTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVE 345
+ G+ Y+ PE+ +G DLW+LG + YE G PPF TY T ++ E
Sbjct: 596 QVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSGHPPFLGETYDITKDKVLNKE 417
Query: 346 FTFPDFVTEGAR----------DLISRLLKHNPSQRPMLREVLEH 380
F P +G+R +L+ LL+ + ++R +++H
Sbjct: 416 FPLPK--VKGSRLSAKPSPEFLNLLESLLQKDSTRRLSWASLVKH 288
>06405
Length = 1965
Score = 97.4 bits (241), Expect = 9e-21, Method: Compositional matrix adjust.
Identities = 68/260 (26%), Positives = 118/260 (45%), Gaps = 9/260 (3%)
Frame = +1
Query: 127 QWALEDFEIGRP--LGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEI 184
+W +E EI LG G++G+VY A K+ I+A+K L E + E I
Sbjct: 241 RWEIERTEIAMKHRLGGGQYGDVYEAMWKRYNKIVAVKTL----KEDTMALNDFLEEAAI 408
Query: 185 QSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTA-TYI-TELAN 242
++HPN+++L G Y++ E+ P G + L+ ++ + TA Y+ T++A+
Sbjct: 409 MKEMKHPNLVQLLGVCTREPPFYIVTEFMPHGNLLDYLRSSTREENGPTALMYMATQIAS 588
Query: 243 ALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGT---LDYLPPE 299
++Y +K IHRD+ N L+ + +K+ADFG + T G + + PE
Sbjct: 589 GMAYLETKNFIHRDLAARNCLVADSNMVKVADFGLARLMKDDTYTAHIGAKFPIKWTAPE 768
Query: 300 MIEGRMHDEKVDLWSLGVLCYEFLV-GKPPFEANTYQETYKRISR-VEFTFPDFVTEGAR 357
+ + D+W+ GVL +E G P+ E Y + R P
Sbjct: 769 GLAFNRFSTRSDIWAFGVLLWELATYGMSPYPGVELTEVYHLLERGYRMERPPGTPADVY 948
Query: 358 DLISRLLKHNPSQRPMLREV 377
L+ + + +P RP +E+
Sbjct: 949 ILMLKCWQWDPKDRPTFKEI 1008
>09007
Length = 1440
Score = 94.4 bits (233), Expect = 8e-20, Method: Compositional matrix adjust.
Identities = 71/264 (26%), Positives = 122/264 (46%), Gaps = 20/264 (7%)
Frame = -1
Query: 135 IGRPLGKGKFGNVYLA---REKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHP 191
+ + LG+G FG V A E K +A+K L K ++ K G E +E I L H
Sbjct: 867 LSKSLGQGHFGTVRQAIWTAESGEKVQVAVKCLSKDKIHKDGQE--FLKETAIMQMLDHE 694
Query: 192 NILRLYGYFHD-ATRVYLILEYAPLGTVYRELQKLS---KFDEQRTATYITELANALSYC 247
NI+R+YG D + L+ E AP+ ++ ++++S F R + ++ + +SY
Sbjct: 693 NIVRVYGVVMDNGADIMLVTELAPMRSLLECVKEVSARVDFSVPRLCDFSQQVCDGMSYL 514
Query: 248 HSKRVIHRDIKPENLLLGSAGELKIADFGWSV-------HAPSSRRTTLCGTLDYLPPEM 300
SKR++HRD+ N+LL S ++KI+D G S + S + L + + PE
Sbjct: 513 ESKRLVHRDLAARNILLFSKSKVKISDVGVSGALGAGKEYYQSQQTIHLQNAVAWCAPES 334
Query: 301 IEGRMHDEKVDLWSLGVLCYEFLV-GKPPFEANTYQETYKRIS-----RVEFTFPDFVTE 354
D+W+ GVL +EF G P+ Q+ + + R+E PD +
Sbjct: 333 FRNLCFSSASDVWAFGVLLWEFFTHGFQPWAGLNGQQIMEAVDAPQSQRLE--QPDLCPK 160
Query: 355 GARDLISRLLKHNPSQRPMLREVL 378
++ + + P +RP ++
Sbjct: 159 EYYAVMLKCWEQEPQRRPTFSQLF 88
>13592
Length = 980
Score = 93.2 bits (230), Expect = 2e-19, Method: Compositional matrix adjust.
Identities = 68/270 (25%), Positives = 128/270 (47%), Gaps = 14/270 (5%)
Frame = +2
Query: 139 LGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYG 198
+G+G+FG VY A + ++A+K + E +++ + E++I ++H N++R YG
Sbjct: 8 IGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETRALKN-VAEELKILEGIKHKNLVRYYG 184
Query: 199 YFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIK 258
+ + +E GT+ ++ E + + +L + ++ H ++HRDIK
Sbjct: 185 IEVHREELLIFMELCSEGTLESLVELTGGLPEALSRRFTAQLLSGVAELHKHGIVHRDIK 364
Query: 259 PENL-LLGSAGELKIADFGWSVHAPSSRRTTL-------CGTLDYLPPEMI---EGRMHD 307
N+ L+ + LK+ DFG +V + TT+ GT Y+ PE+ H
Sbjct: 365 TANIFLVDGSNSLKLGDFGSAVKIQA--HTTVPGELQGYVGTQAYMAPEVFTKTNSDGHG 538
Query: 308 EKVDLWSLGVLCYEFLVGKPP---FEANTYQETYKRISRVEFTFPDFVTEGARDLISRLL 364
D+WS+G + E GK P F++N +Q +K + P+ +++ D I L
Sbjct: 539 RLADIWSVGCVVVEMASGKRPWAQFDSN-FQIMFKVGMGEKPQAPESLSQEGHDFIDHCL 715
Query: 365 KHNPSQRPMLREVLEHPWITANSSKPSNCQ 394
+H+P QR E+LE + + + N +
Sbjct: 716 QHDPKQRLSAIELLEQNFCKSGRDEECNSE 805
>13212
Length = 1067
Score = 92.4 bits (228), Expect = 3e-19, Method: Compositional matrix adjust.
Identities = 60/188 (31%), Positives = 96/188 (51%), Gaps = 10/188 (5%)
Frame = -1
Query: 206 VYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLG 265
V+ +L + L ++ +L+K E + E+ AL + H VIHRDIK N+LL
Sbjct: 1049 VFRVLWWGALDSIMVDLEK--PMTEAQICYVCHEMCMALDFLHRHHVIHRDIKAGNVLLT 876
Query: 266 SAGELKIADFGWSVHAPSS--RRTTLCGTLDYLPPEMI-----EGRMHDEKVDLWSLGVL 318
GE+K+ADFG S + +R T GT ++ PE++ + +D K D+WSLGV
Sbjct: 875 IDGEVKLADFGVSAKNTQTQQKRDTFIGTPYWMAPEVVLCETLKDTPYDFKADIWSLGVT 696
Query: 319 CYEFLVGKPPFEANTYQETYKRISRVE---FTFPDFVTEGARDLISRLLKHNPSQRPMLR 375
EF +PP + +I + + P T+ +D I++ L +P+ RP
Sbjct: 695 LIEFAQIEPPNKEMHPMRVLIKIHKSDPPTLEKPKKWTKLFKDFIAKCLVKDPNLRPTAA 516
Query: 376 EVLEHPWI 383
E+LEHP++
Sbjct: 515 ELLEHPFM 492
>01392
Length = 1806
Score = 90.5 bits (223), Expect = 1e-18, Method: Compositional matrix adjust.
Identities = 57/189 (30%), Positives = 90/189 (47%), Gaps = 34/189 (17%)
Frame = -1
Query: 230 EQRTATYITELANALSYCHSKRVIHRDIKPENLL---LGSAGELKIADF----GWSVHAP 282
E+ + + +A AL + HSK + HRD+KPEN+L L +KI DF G S
Sbjct: 1794 EREASLVVRHIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGISCDGD 1615
Query: 283 SSRRTTL---CGTLDYLPPEMIEGRM-----HDEKVDLWSLGVLCYEFLVGKPPFEANTY 334
++ L G+ +Y+ PE+++ + +D++ DLWSLG++ Y L G PPF
Sbjct: 1614 GTKTPELLTPVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILYIMLCGYPPFYGQCG 1435
Query: 335 QET---------------YKRISRVEFTFPD----FVTEGARDLISRLLKHNPSQRPMLR 375
++ + I + FP ++ A+DLI LL P +R
Sbjct: 1434 EDCGWNRGEACHDCQDMLFNSIQDGHYKFPSQEWTSISSSAKDLIRHLLVREPRKRYSAA 1255
Query: 376 EVLEHPWIT 384
+VL+HPWI
Sbjct: 1254 DVLKHPWIC 1228
>01756
Length = 1858
Score = 87.0 bits (214), Expect = 1e-17, Method: Compositional matrix adjust.
Identities = 66/222 (29%), Positives = 106/222 (47%), Gaps = 16/222 (7%)
Frame = -3
Query: 139 LGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYG 198
+G+G FG V+ AR K++K ++A+K + EK G RE++I L H N++ L
Sbjct: 1718 IGQGTFGEVFKARCKKTKQVVAMKKVLMDN-EKEGFPITALREIKILQLLNHENVVDLIE 1542
Query: 199 YFH----DATR----VYLILEYA--PLGTVYRELQKLSKFDEQRTATYITELANALSYCH 248
A R YL+ E+ L + + + E + + +L N L Y H
Sbjct: 1541 ICSTKATSANRYKSMFYLVFEFCEHDLAGLLSNMSVVFNLPEIKEV--MKQLMNGLYYIH 1368
Query: 249 SKRVIHRDIKPENLLLGSAGELKIADFG----WSVHAPS-SRRTTLCGTLDYLPPEMIEG 303
+++HRD+K N+L+ G LK+ADFG +SV+ +R T TL Y PPE++ G
Sbjct: 1367 RNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRPPELLLG 1188
Query: 304 -RMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRV 344
R + +D W G + E P + T Q I+++
Sbjct: 1187 DRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQNQLTLITQL 1062
>13066
Length = 551
Score = 87.0 bits (214), Expect = 1e-17, Method: Compositional matrix adjust.
Identities = 50/164 (30%), Positives = 87/164 (53%), Gaps = 6/164 (3%)
Frame = +3
Query: 159 LALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTV 218
LA K++ K + VE RE+++ + L HP I++++ + ++ + +A G +
Sbjct: 60 LACKIIDKEKAPVDFVEKFFPRELDLLTKLDHPYIIQIHSILQRXPKNFIFMRFAERGDL 239
Query: 219 YRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS 278
+Q++ E++ + ++ AL+Y HS V HRD+K EN+LL S +K+ADFG++
Sbjct: 240 LTYIQEVGFVKEKQAKIWFYQMTTALNYLHSYDVAHRDLKCENILLSSHFNVKLADFGFA 419
Query: 279 VHAPSS-----RRTTLCGTLDYLPPEMIEGRMHDEKV-DLWSLG 316
+ T CG+ Y PE++ G + KV D WSLG
Sbjct: 420 CACITESGEKYMSRTYCGSAAYAAPEIVYGAPYAPKVADAWSLG 551
>11780
Length = 1713
Score = 80.1 bits (196), Expect(2) = 2e-17, Method: Compositional matrix adjust.
Identities = 57/202 (28%), Positives = 100/202 (49%), Gaps = 7/202 (3%)
Frame = +3
Query: 121 EESKKRQW--ALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQL 178
+E K W A +D EIG +GKG FG+VY + V K +K E
Sbjct: 561 QEFKSGGWVIAXQDLEIGEAIGKGDFGDVYKGMYRGQP------VAIKQLKDKDRGEQSF 722
Query: 179 RREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSK--FDEQRTATY 236
+E + + LRH N++RL G T ++L+ E+ G + L+ + ++ +
Sbjct: 723 LQEASVMTSLRHDNLVRLIGVVLGET-IFLVTEFMGKGNLVEYLRSRGRSVITKKDQINF 899
Query: 237 ITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYL 296
T+ A+ Y SKR++HRD+ N+L+ G+ K++DFG + S +T++ + +
Sbjct: 900 ATDTCAAMEYLESKRLVHRDLAARNVLVHDDGKAKVSDFGLAKFGDFS-QTSVKFPIKWT 1076
Query: 297 PPEMI-EGRMHDE--KVDLWSL 315
PE + E ++H + V+LW +
Sbjct: 1077APEALRENKIH*QVRHVELWHI 1142
Score = 26.6 bits (57), Expect(2) = 2e-17, Method: Compositional matrix adjust.
Identities = 16/72 (22%), Positives = 33/72 (45%), Gaps = 2/72 (2%)
Frame = +1
Query: 309 KVDLWSLGVLCYE-FLVGKPPFEANTYQETYKRISR-VEFTFPDFVTEGARDLISRLLKH 366
K D+WS G+L +E + G+ P+ + + R P+ ++ + +
Sbjct: 1114 KSDMWSFGILLWEIYSFGRVPYPRIPLTDVVMHVERGYRMEAPEGCPPEIYSIMKQAWEL 1293
Query: 367 NPSQRPMLREVL 378
+P++RP + VL
Sbjct: 1294 DPNERPTFKSVL 1329
>04591
Length = 1117
Score = 86.3 bits (212), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 60/184 (32%), Positives = 88/184 (47%), Gaps = 12/184 (6%)
Frame = -2
Query: 171 KAGVEHQLRREVEIQSHLRHPNILRLYGYFHD--------ATRVYLILEYAP--LGTVYR 220
K G RE++I L H N+++L H + YLI EY L +
Sbjct: 1101 KEGFPITALREIKILQQLEHENVVQLQEICHTQAGPYNRYKSTFYLIFEYCDYDLAGLLN 922
Query: 221 ELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSV- 279
L+ KF +++L N L Y H+K+++HRDIK N+LL G LK+ADFG S
Sbjct: 921 NLR--VKFSLADKKNLMSQLLNGLFYIHTKQILHRDIKAANILLTRDGVLKLADFGLSRP 748
Query: 280 HAPSSRRTTLCGTLDYLPPEMIEG-RMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETY 338
S R T TL Y PPE++ G R + ++D+W +G + E KP + + Q
Sbjct: 747 WVKSKRLTNRVVTLWYRPPELLLGEREYGPEIDMWGVGCIMAEMWSRKPLMQGRSEQHQL 568
Query: 339 KRIS 342
I+
Sbjct: 567 SLIT 556
>01718
Length = 959
Score = 85.9 bits (211), Expect = 3e-17, Method: Compositional matrix adjust.
Identities = 62/209 (29%), Positives = 99/209 (47%), Gaps = 11/209 (5%)
Frame = +3
Query: 130 LEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLR 189
L+DF I +G G F V+ + + ++ALK+ H + REV++ + L+
Sbjct: 147 LDDF-ICEKIGAGFFSEVFKVTHRITGQVMALKMN-----TMTSNRHNMLREVQLLNRLQ 308
Query: 190 HPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTAT----YITELANALS 245
H NILR G +++ + EY P G + Q L K DE+ T LA L
Sbjct: 309 HANILRFMGVCVHEGQLHALTEYIPSGNLE---QLLEKKDEELPWTQRIQLTLGLARGLD 479
Query: 246 YCHSKRVIHRDIKPENLLL----GSAGELKIADFGWSVHAP---SSRRTTLCGTLDYLPP 298
Y HS R IHRD+ +N+L+ IADFG + P + G+ ++ P
Sbjct: 480 YLHSTRFIHRDLTSKNILIRREDNHGYHAVIADFGLATKIPDPLDKEKLPTVGSPYWMAP 659
Query: 299 EMIEGRMHDEKVDLWSLGVLCYEFLVGKP 327
E++ G ++E+ DL+S+G++ E P
Sbjct: 660 EVLNGHFYNERADLFSVGIIMCEITARIP 746
>17975
Length = 449
Score = 85.1 bits (209), Expect = 4e-17, Method: Compositional matrix adjust.
Identities = 51/137 (37%), Positives = 80/137 (58%), Gaps = 2/137 (1%)
Frame = +3
Query: 144 FGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDA 203
F V LAR + +A+KV+ K +L++ H L +EV ++HPN++RLY
Sbjct: 6 FAVVKLARHVFTGEKVAVKVIDKTKLDEVSRSH-LFQEVRCMKLVQHPNVVRLYEVIDTQ 182
Query: 204 TRVYLILEYAPLGTVYRELQKLSKFDEQRTAT-YITELANALSYCHSKRVIHRDIKPENL 262
T++YLILE G +Y + + S E++ A Y ++ A+SYCH V+HRD+KPEN+
Sbjct: 183 TKLYLILELGDGGDMYDYIMRHSGGLEEKLAKRYFRQIVEAISYCHKLHVVHRDLKPENV 362
Query: 263 LLGSA-GELKIADFGWS 278
+ G +K+ DFG+S
Sbjct: 363 VFFEKPGLVKLTDFGFS 413
>31885
Length = 529
Score = 84.3 bits (207), Expect = 7e-17, Method: Compositional matrix adjust.
Identities = 48/158 (30%), Positives = 81/158 (51%), Gaps = 6/158 (3%)
Frame = -2
Query: 182 VEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELA 241
V++ + L HP ++ L+ F D ++++++ G + +Q+ F E Y+ +LA
Sbjct: 519 VDMLTRLDHPFLVNLWYAFQDEEDLFMVVDLFLGGDLRYHMQQEVSFREDCVKFYLCQLA 340
Query: 242 NALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSR-RTTLCGTLDYLPPEM 300
L Y S++++HRDIKP+N+LL G + DF + T+ GT Y+ PE+
Sbjct: 339 LVLDYLRSQKIVHRDIKPDNILLDEQGHCHVTDFNIATQLEDDELATSTSGTRPYMAPEV 160
Query: 301 I-----EGRMHDEKVDLWSLGVLCYEFLVGKPPFEANT 333
E R + VD WSLGV +E L + PF ++
Sbjct: 159 YGVAINERRGYGFPVDWWSLGVSLFELLKKRRPFSVHS 46
>27546
Length = 426
Score = 82.8 bits (203), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 42/120 (35%), Positives = 70/120 (58%)
Frame = -1
Query: 159 LALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTV 218
LA K++ KA+ V+ RE+EI + L HPNI++++ ++++ + YA G +
Sbjct: 396 LACKIIDKAKAPIDFVKKFFPRELEILTRLDHPNIIQIHSILQRGPKIFIFMRYAEKGDM 217
Query: 219 YRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS 278
++K DE +T + ++A AL Y HS + HRD+K EN+LL +KIADFG++
Sbjct: 216 LSHIKKTGPIDEAQTKVWFFQMAKALQYLHSHDIAHRDLKCENILLSKRLNVKIADFGFA 37
>00486
Length = 797
Score = 82.0 bits (201), Expect = 3e-16, Method: Compositional matrix adjust.
Identities = 35/84 (41%), Positives = 53/84 (63%)
Frame = -2
Query: 288 TLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFT 347
T CGT++Y+ PE++ H + VD WSLG L Y+ L G PPF A ++T +I + +
Sbjct: 781 TFCGTIEYMAPEILTRTGHGKAVDWWSLGALMYDMLTGSPPFTAENRKKTIDKILKGKLN 602
Query: 348 FPDFVTEGARDLISRLLKHNPSQR 371
P ++T AR LI +LL+ NP++R
Sbjct: 601 LPPYLTNEARGLIKKLLRKNPAER 530
>21079
Length = 878
Score = 81.6 bits (200), Expect = 6e-16, Method: Compositional matrix adjust.
Identities = 42/148 (28%), Positives = 79/148 (53%), Gaps = 4/148 (2%)
Frame = +1
Query: 190 HPNILRLYGYFHDATRVYLILEYAPLGTVY-RELQKLSKFDEQRTATYITELANALSYCH 248
HP +L L+ F + L++E+ G ++ R ++ E+ ++ ++ + + Y H
Sbjct: 1 HPKLLMLWDAFEAPRTMVLVMEFVGAGELFERVIRDDFVLTERDCVHFVRQICSGVGYMH 180
Query: 249 SKRVIHRDIKPENLLLGS--AGELKIADFGWS-VHAPSSRRTTLCGTLDYLPPEMIEGRM 305
++ ++H D+KPEN+L S + ++KI DFG + + P L GT +++ PE++
Sbjct: 181 TQSILHLDLKPENVLCVSDNSNQIKIIDFGLARFYKPGDSLQVLFGTPEFIAPEVVNYDE 360
Query: 306 HDEKVDLWSLGVLCYEFLVGKPPFEANT 333
+ D+WS+GV+CY L G P T
Sbjct: 361 INFTTDMWSIGVICYILLSGLSPSRVTT 444
>00392
Length = 668
Score = 80.5 bits (197), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 48/175 (27%), Positives = 91/175 (52%), Gaps = 9/175 (5%)
Frame = +3
Query: 177 QLRREVEIQSHLRHPNILRLYGYFHDATR-----VYLILEYAPLGTVYRELQKLSKFDEQ 231
+ + E E+ L+HPNI+R + Y+ + + L+ E GT+ L++ K + +
Sbjct: 69 RFKEEAEMLKELQHPNIVRFFDYWEEHNHRNRKVIILVTELMTSGTLKTYLKRFKKPNVK 248
Query: 232 RTATYITELANALSYCHSKR--VIHRDIKPENLLL-GSAGELKIADFGWSVHAPSSRRTT 288
+ ++ L + H++ VIHRD+K +N+ + G G +KI D G + S +
Sbjct: 249 ILKNWCRQVLKGLYFLHTRTPPVIHRDLKCDNIFITGPTGSVKIGDLGLATLKNQSFAKS 428
Query: 289 LCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPF-EANTYQETYKRIS 342
+ GT +++ PEM E +DE VD+++ G+ E + P+ E + + YKR++
Sbjct: 429 VIGTPEFMAPEMYEEH-YDEAVDVYAFGMCMLEMASSEYPYSECSNAAQIYKRVT 590
>01966
Length = 1735
Score = 79.0 bits (193), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 42/135 (31%), Positives = 70/135 (51%), Gaps = 4/135 (2%)
Frame = -1
Query: 173 GVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEY--APLGTVYRELQKLSKFDE 230
GV RE+ + LRH NI+ L + R++L+ E+ L + + D
Sbjct: 1588 GVPSSAIREIAMLRELRHTNIVCLEDVIMEDERLFLVFEFLSMDLKMYIDKFPEGVVLDR 1409
Query: 231 QRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGW--SVHAPSSRRTT 288
+ +Y+ ++ +++CH +R++HRD+KP+NLL+ G +KIADFG + P T
Sbjct: 1408 RLVKSYVFQIVTGINFCHQRRIVHRDLKPQNLLINHTGAIKIADFGMARTFALPVRAYTH 1229
Query: 289 LCGTLDYLPPEMIEG 303
TL Y PE++ G
Sbjct: 1228 EVVTLWYRAPEILMG 1184
>19761
Length = 473
Score = 76.3 bits (186), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 40/142 (28%), Positives = 77/142 (54%), Gaps = 4/142 (2%)
Frame = -3
Query: 230 EQRTATYITELANALSYCHSKR--VIHRDIKPENLLLGSAGELKIADFGWS--VHAPSSR 285
E+ ++ + A+AL+Y H+ ++HRD+KP+N+ + G++++ D G + + P+
Sbjct: 426 ERLIVCWLMQTASALNYMHTHTPVILHRDLKPQNIYVTEKGDVRLGDLGLARKLTGPADF 247
Query: 286 RTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVE 345
T+ GT+ YL PE++ + ++ K D+WSLG + Y+ K E + + +
Sbjct: 246 ATSQVGTIMYLSPEILSQQPYNSKSDIWSLGCVFYDITGKKGSDEMGVMFLLVQVMGGRK 67
Query: 346 FTFPDFVTEGARDLISRLLKHN 367
PD ++ RD ISR+L +
Sbjct: 66 LPLPDHYSQEFRDTISRMLTKD 1
>19094
Length = 898
Score = 70.1 bits (170), Expect(2) = 6e-14, Method: Compositional matrix adjust.
Identities = 39/103 (37%), Positives = 57/103 (55%), Gaps = 2/103 (1%)
Frame = +1
Query: 230 EQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS--VHAPSSRRT 287
E+ AT + L Y HS+R IHRDIK N+LL + G K+ADFG + + ++R
Sbjct: 55 EREIATILYYTLKGL*YLHSRRKIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRN 234
Query: 288 TLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFE 330
T+ GT ++ PE+I+ +D D+WSLG+ E G E
Sbjct: 235 TVIGTPYWMAPEVIQEIGYDCVADIWSLGITALEMAEGNLHME 363
Score = 24.6 bits (52), Expect(2) = 6e-14, Method: Compositional matrix adjust.
Identities = 12/38 (31%), Positives = 19/38 (50%)
Frame = +3
Query: 346 FTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWI 383
F PD + D +S+ L NP R ++L+H +I
Sbjct: 417 FRQPDKWSTEFIDFVSKCLVKNPENRATAVDLLQHDFI 530
>26560
Length = 398
Score = 74.7 bits (182), Expect = 7e-14, Method: Composition-based stats.
Identities = 40/131 (30%), Positives = 67/131 (51%), Gaps = 1/131 (0%)
Frame = -1
Query: 218 VYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGW 277
++ L + F E+ Y E+ L + HS+ V++RD+KP N+LL G ++I+D G
Sbjct: 395 LHYHLSQHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGL 216
Query: 278 SVHAPSSRRTTLCGTLDYLPPE-MIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQE 336
+ R GT Y+ PE +++G+ +D D +S G + Y+ L G PF + +
Sbjct: 215 ACDFSKKRPHASVGTHGYMAPEVLMKGQSYDSSADWFSFGCMLYKLLKGHSPFR--QHNQ 42
Query: 337 TYKRISRVEFT 347
RI R+ T
Sbjct: 41 GQARIDRMTMT 9
>29581
Length = 1278
Score = 72.0 bits (175), Expect = 4e-13, Method: Compositional matrix adjust.
Identities = 63/235 (26%), Positives = 101/235 (42%), Gaps = 38/235 (16%)
Frame = -2
Query: 187 HLRHPNILRL----YGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELAN 242
+LRH NI++L G D+ ++L++EY + F E + + +L
Sbjct: 1187 NLRHQNIVQLQEVVVGKSLDS--LFLVMEYCEQDLASLLDNMPAPFSESQVKCIVLQLLK 1014
Query: 243 ALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVH--APSSRRTTLCGTLDYLPPEM 300
L Y H +IHRD+K NLL+ G +KIADFG + + P T TL Y PE+
Sbjct: 1013 GLRYLHEAFIIHRDLKVSNLLMTDKGCVKIADFGLARNYGKPQKPMTPKVVTLWYRAPEL 834
Query: 301 IEG-RMHDEKVDLWSLGVLCYEFLVGKPPFEANT-------------------------- 333
+ G + H +D+WS G + E L KP +
Sbjct: 833 LFGSKTHSTAIDMWSAGCILGELLGHKPLMPGRSDLQQIELIMELLGTPNDTIWPGFSQL 654
Query: 334 ---YQETYKR--ISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWI 383
Q T K+ + + TFP +++E L++ L ++P +R + LEH +
Sbjct: 653 PAFEQFTLKKQPYNNLRHTFP-WLSESGIRLLNGLFMYHPQKRATAEDCLEHSYF 492
>20152
Length = 445
Score = 68.9 bits (167), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 32/96 (33%), Positives = 50/96 (52%), Gaps = 1/96 (1%)
Frame = +1
Query: 298 PEMIEGRMHDE-KVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGA 356
PE++ G +D VD+WSLGV+ Y +VG+ PF+ ET I + P ++
Sbjct: 1 PEILLGDSYDAPAVDVWSLGVILYMLVVGEAPFQEANDSETLTMIMDCRYQIPPHISHKC 180
Query: 357 RDLISRLLKHNPSQRPMLREVLEHPWITANSSKPSN 392
+DLI ++L+ P R L +L HPW+ P+
Sbjct: 181 QDLIEKMLQREPVDRASLPHILAHPWLNDGDLTPTT 288
>27405
Length = 532
Score = 67.8 bits (164), Expect = 7e-12, Method: Compositional matrix adjust.
Identities = 47/175 (26%), Positives = 84/175 (48%), Gaps = 5/175 (2%)
Frame = -3
Query: 144 FGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLR----HPNILRLYGY 199
FG VY R+ + + A+K L K +++ G E E + S + P I+ +
Sbjct: 527 FGEVYGCRKADTGKMYAMKCLDKKRIKMKGGETLALNERIMLSLVSTGEGSPFIVCMTYA 348
Query: 200 FHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKP 259
F ++ IL+ G ++ L + F E+ Y E+ L + HS+ V++RD+KP
Sbjct: 347 FQTPEKLCFILDLMNGGDLHYHLSQHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKP 168
Query: 260 ENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPE-MIEGRMHDEKVDLW 313
N+LL G ++I+D G + + GT Y+ PE +++G+ +D D +
Sbjct: 167 ANILLDENGHVRISDLGLACDFSKKKPHASVGTHGYMAPEVLMKGQAYDSSADWF 3
>26711
Length = 405
Score = 65.9 bits (159), Expect = 3e-11, Method: Composition-based stats.
Identities = 39/132 (29%), Positives = 72/132 (54%), Gaps = 8/132 (6%)
Frame = -2
Query: 237 ITELANALSYCHSKRVIHRDIKPENLLLG--SAGELKIADFGWSVHAPSSRRTTLC-GTL 293
+ ++ + L + H++ V+H D+KP NLLL +++ DFG + + T L GT
Sbjct: 398 VKQVLDILQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARKLYPPQETFLNHGTP 219
Query: 294 DYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTF---PD 350
+ PE ++ + D+W +GVL Y L G+ PF+A++ E+ K+ +++F P
Sbjct: 218 GFTSPEALDVKPISTASDVWGVGVLAYILLSGQSPFQADSATESLKKTQTCDWSFDVCPS 39
Query: 351 F--VTEGARDLI 360
F +++ A+D I
Sbjct: 38 FSNMSQDAKDFI 3
>19301
Length = 712
Score = 65.1 bits (157), Expect = 5e-11, Method: Compositional matrix adjust.
Identities = 33/101 (32%), Positives = 56/101 (55%), Gaps = 2/101 (1%)
Frame = +2
Query: 180 REVEIQS--HLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYI 237
+E +I++ L HPNI+ G A +I+EY P G +Y L+ + +
Sbjct: 410 KETDIRNLRKLNHPNIISFKGVCTQAPCYCIIMEYCPYGQLYEVLRDGKEIPPALVLDWS 589
Query: 238 TELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS 278
++A+ ++Y HS ++IHRD+K N+L+ +KI+DFG S
Sbjct: 590 KQIASGMNYLHSHKIIHRDLKSPNVLVAKNDVVKISDFGTS 712
>38560
Length = 479
Score = 64.7 bits (156), Expect = 6e-11, Method: Compositional matrix adjust.
Identities = 33/111 (29%), Positives = 58/111 (52%), Gaps = 1/111 (0%)
Frame = -3
Query: 287 TTLCGTLDYLPPEMIEGRMH-DEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVE 345
TT CG+ Y PE+I G + + D+WS+GVL Y L G PF+ ++ + +
Sbjct: 411 TTCCGSPAYAAPELISGLEYLGSEADIWSMGVLLYALLCGYLPFDDEKXSHL*QKNQKRK 232
Query: 346 FTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQNK 396
P++++E L+ +L+ +PS R +R +L+H W+ + P +K
Sbjct: 231 DEVPEWLSEDTTKLLEGMLQTDPSHRITIRRLLDHHWLNQGFNVPVEWASK 79
>14477
Length = 493
Score = 63.9 bits (154), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 44/142 (30%), Positives = 73/142 (51%), Gaps = 2/142 (1%)
Frame = -1
Query: 139 LGKGKFGNVY--LAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRL 196
LG G FG+V + R + +A+KVL A L+ + V+ +L +E E+ + H +I+RL
Sbjct: 466 LGAGNFGSVMKGVCRLDDREIPVAIKVLKNADLDPS-VQSELIKEAEVMKKMDHMHIVRL 290
Query: 197 YGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRD 256
G T + L+LE A LG + + L K + +++ + Y + + +HRD
Sbjct: 289 IGLCEGET-MMLVLELAKLGPLNKFLPKNKHLPLWNILELMWQVSQGMEYLEANKFVHRD 113
Query: 257 IKPENLLLGSAGELKIADFGWS 278
+ N+LL KI+DFG S
Sbjct: 112 LAARNILLCDEHFAKISDFGMS 47
>04852
Length = 1462
Score = 63.9 bits (154), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 40/151 (26%), Positives = 75/151 (49%), Gaps = 5/151 (3%)
Frame = +1
Query: 235 TYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTL- 293
+Y ++A + + S++ IHRD+ N+L+ LKIADFG S ++ + G L
Sbjct: 337 SYAFQIARGMEFLASRKCIHRDLAARNVLVTEEHVLKIADFGLSRTGDYYKKRS-GGRLP 513
Query: 294 -DYLPPEMIEGRMHDEKVDLWSLGVLCYE-FLVGKPPFEANTYQETYKRISRVEFTF--P 349
++ PE + + K D+WS GV+ +E F +G P+ + +E Y ++ + P
Sbjct: 514 VKWMAPEALFDMRYTTKSDVWSFGVVLWEIFSLGGMPYASIPNEELYSKLLDDAYRMPRP 693
Query: 350 DFVTEGARDLISRLLKHNPSQRPMLREVLEH 380
+ + ++ R + PS RP +++ H
Sbjct: 694 ELASGNLYAIMERCWLNRPSDRPEFSQLVGH 786
>06358
Length = 1517
Score = 63.5 bits (153), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 65/273 (23%), Positives = 121/273 (44%), Gaps = 40/273 (14%)
Frame = +3
Query: 140 GKGKFGNVYLAREKQSK-----FILALKVLFK-AQLEKAGVEHQLRREVEIQSHLRHPNI 193
G G V+ A +K +K F+ K + + ++ ++ + LR V+ + LRHP I
Sbjct: 33 GPGLLWKVFAASKKSTKEEASVFVFEKKSVDRYSRRDREAIVEVLRVGVQQLTKLRHPKI 212
Query: 194 LRLYGYFHD-------------ATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITEL 240
L + + A+ ++ + + + TV +ELQ +D + + ++
Sbjct: 213 LAVINPLEESRETLAFATEPVFASLANVLGDLSSIXTVPKELQDYQLYDVE-IKHGLLQV 389
Query: 241 ANALSYCHSK-RVIHRDIKPENLLLGSAGELKIADFGWSVHA--PSSR---------RTT 288
AL + H+ +++HR++ PE ++L G K+A + + V + P S R+
Sbjct: 390 TEALGFLHNDAKMMHRNVCPEAIMLTKLGSWKLAGYEFCVRSSDPQSTDPSYPFYEWRSD 569
Query: 289 LCGT----LDYLPPEMIEGRMHDEKVDLWSLGVLCYE-FLVGKPPFEAN----TYQETYK 339
+ LD++ PE + D++SLG+L Y F GKP FE N ++ +
Sbjct: 570 IAPVTQPHLDFMAPEYVLTMQCGTGSDMFSLGLLVYSVFAKGKPLFECNGELSAFKSNAE 749
Query: 340 RISRVEFTFPDFVTEGARDLISRLLKHNPSQRP 372
+ + + V E RD + LL P+ RP
Sbjct: 750 ELRHMRVSLLGVVPEDLRDHVKLLLNIEPAVRP 848
>04138
Length = 800
Score = 63.5 bits (153), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 51/177 (28%), Positives = 72/177 (40%), Gaps = 40/177 (22%)
Frame = +1
Query: 244 LSYCHSKRVIHRDIKPENLLLGSAGELKIADFG----WSVHAPS-SRRTTLCGTLDYLPP 298
L Y H +++HRD+K N+L+ G LK+ADFG +SV+ +R T TL Y PP
Sbjct: 52 LYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRPP 231
Query: 299 EMIEG-RMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGAR 357
E++ G R + +D W G + E P + T Q I+++ + V G
Sbjct: 232 ELLLGDRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQNQLTLITQLCGSITPEVWPGVT 411
Query: 358 ----------------------------------DLISRLLKHNPSQRPMLREVLEH 380
DL RLLK +PSQR E L H
Sbjct: 412 QLSMYHQIKGALAAGRKNIIRDRFARILKDPYGLDLFERLLKMDPSQRISADEALNH 582
>21808
Length = 1011
Score = 63.2 bits (152), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 43/166 (25%), Positives = 73/166 (43%), Gaps = 5/166 (3%)
Frame = +1
Query: 181 EVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYI-TE 239
E +I LRHP +++LY +++I E G++ LQ + + I +
Sbjct: 82 EAQIMKKLRHPKLIQLYAVCTQDDPIFIITELMKNGSLLEFLQGKGRVLKLPALIDIGAQ 261
Query: 240 LANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGT---LDYL 296
+A ++Y S+ IHRD+ N+L+ +KIADFG + G + +
Sbjct: 262 IACGMAYLESQNYIHRDLAARNILVSDNNTVKIADFGLARVIKEDEYEARVGARFPIKWT 441
Query: 297 PPEMIEGRMHDEKVDLWSLGVLCYEFLV-GKPPFEANTYQETYKRI 341
PE K D+WS G+L E + G+ P+ T E ++
Sbjct: 442 APEAANYNRFTIKSDVWSFGILLTETVTYGRVPYPGMTNAEVLHQV 579
>00715
Length = 1788
Score = 61.6 bits (148), Expect = 5e-10, Method: Compositional matrix adjust.
Identities = 47/177 (26%), Positives = 76/177 (42%), Gaps = 33/177 (18%)
Frame = +1
Query: 188 LRHPNILRLYGY-----FHDATRVYLILEYAP---LGTVYRELQKLSKFDEQRTATYITE 239
LRH N++ + G F D +L +EY L T+ + Q+ D + +
Sbjct: 97 LRHVNVVSILGATSLHRFEDGA--WLAMEYVGPLNLQTILNDHQQ--DIDSSMRLSLALQ 264
Query: 240 LANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVH------------------- 280
+A L Y HS ++H D+KP N LL +L+IADFG H
Sbjct: 265 MARGLHYLHSINIVHLDLKPANCLLTRDLKLRIADFG-CCHQLTPTGLDMGEREGGMAGN 441
Query: 281 ------APSSRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEA 331
+ + L GTL Y PE+++G + D++SLG+ ++ + P+E
Sbjct: 442 ELELTPVQGAWKNELAGTLAYRAPELLKGLQPSVRSDVYSLGITLWQMCTRQGPYEG 612
>14116
Length = 1017
Score = 61.2 bits (147), Expect = 6e-10, Method: Compositional matrix adjust.
Identities = 56/217 (25%), Positives = 96/217 (44%), Gaps = 24/217 (11%)
Frame = -1
Query: 131 EDFEIGRPLGKGKFGNV---YLAR-EKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQS 186
E +G +GKG FG V +L E++ ++A+K L RE+E+QS
Sbjct: 636 EFLTMGEEIGKGNFGCVKRGFLTLPEQKGDILVAVKTLHNNN----------PREIELQS 487
Query: 187 HLR---------HPNILRLYGY---FHDATRVYL-ILEYAPLGTVYRELQKLSKFDEQRT 233
L+ H N+L L G D V L +++ L T R+ Q +
Sbjct: 486 FLQEALIMKDFHHSNVLTLIGICLNLDDMPLVVLPFMKHGDLLTYIRDDQHQPTIKD--L 313
Query: 234 ATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS-------VHAPSSRR 286
Y ++A + Y + +HRD+ N +L +K+ADFG + ++ +++
Sbjct: 312 IMYGVDIARGMDYLAGLKFVHRDLAARNCMLDEDFHVKVADFGLARDIYEKEYYSSENKK 133
Query: 287 TTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFL 323
L + ++ E +E +D K D+WS GV+ +E L
Sbjct: 132 AKL--PVKWMALESLEKGNYDSKTDVWSYGVVLWELL 28
>28157
Length = 400
Score = 61.2 bits (147), Expect = 8e-10, Method: Compositional matrix adjust.
Identities = 39/104 (37%), Positives = 57/104 (54%), Gaps = 7/104 (6%)
Frame = +3
Query: 180 REVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLS---KFDEQRTATY 236
+E++ S + HPNI+ LYG D V L++EYA G++Y L ++ +
Sbjct: 57 QELKQLSRVSHPNIVCLYGACRDHP-VCLVMEYAEGGSLYNVLHGSGPQPQYTAAHAMNW 233
Query: 237 ITELANALSYCHS---KRVIHRDIKPENLLLGSAG-ELKIADFG 276
+ + A + Y H K +IHRD+KP NLLL G +LKI DFG
Sbjct: 234 LLQCALGVEYLHGMKPKALIHRDLKPPNLLLIQCGTKLKICDFG 365
>12672
Length = 773
Score = 60.8 bits (146), Expect = 9e-10, Method: Compositional matrix adjust.
Identities = 45/161 (27%), Positives = 69/161 (42%), Gaps = 24/161 (14%)
Frame = +3
Query: 241 ANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTT------LCGTLD 294
A+ + Y + +HRDIK N+LL S K+ DF V APS T + GT
Sbjct: 21 ASGIQYLNDNGHVHRDIKTANILLDSEYTAKVGDFATVVSAPSGEGKTVQNASVVIGTAA 200
Query: 295 YLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTY------------------QE 336
YL PE I + K+D +S GV+ E + G A Y +E
Sbjct: 201 YLAPEAIHFDVS-TKLDSYSFGVVLLEVITG---LVAQDYSREERTLSSHIMENVEEPEE 368
Query: 337 TYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREV 377
+ + + T+PD + D+ R L + QRP ++++
Sbjct: 369 IHDFVDQSAGTWPDGAVDKLYDISMRCLNLSKKQRPNVKDI 491
>07940
Length = 1336
Score = 60.8 bits (146), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 36/100 (36%), Positives = 54/100 (54%), Gaps = 5/100 (5%)
Frame = -3
Query: 235 TYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS--VHAPSSRRTTLCGT 292
+Y ++A + Y SK+ IHRD+ N+L+ LKIADFG + + R T G
Sbjct: 335 SYAYQVARGMEYLASKQCIHRDLAARNVLVAEEYVLKIADFGLTRNLQQFDYYRKTTDGR 156
Query: 293 L--DYLPPEMIEGRMHDEKVDLWSLGVLCYE-FLVGKPPF 329
L ++ PE + R + K D+WS GVL +E F +G P+
Sbjct: 155 LPVKWMAPEALFDRKYTSKSDVWSYGVLLWEIFTLGGNPY 36
Score = 34.3 bits (77), Expect = 0.088, Method: Compositional matrix adjust.
Identities = 28/95 (29%), Positives = 49/95 (51%), Gaps = 7/95 (7%)
Frame = -3
Query: 131 EDFEIGRPLGKGKFGNVYLAREKQSKF------ILALKVLFKAQLEKAGVEHQLRREVEI 184
E +G LG+G FG V + E F +A+K+L + ++ ++ L RE+E+
Sbjct: 842 ERLVLGDRLGEGAFGLV-MKGEAMGIFKDNNSVTVAVKMLKEDATDREMMD--LIREMEM 672
Query: 185 QSHL-RHPNILRLYGYFHDATRVYLILEYAPLGTV 218
+ +H NI+ L G +Y+I+E+AP G +
Sbjct: 671 MKVIGKHKNIINLLGCCTQRGALYVIVEFAPHGNL 567
>03508
Length = 1463
Score = 60.8 bits (146), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 31/109 (28%), Positives = 57/109 (52%), Gaps = 3/109 (2%)
Frame = +1
Query: 223 QKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAG-ELKIADFGWS-VH 280
Q F + Y+ EL AL +CHS ++HRD+KP N+++ +L++ D+G + +
Sbjct: 847 QLYQTFTDYDIRFYLYELMKALDFCHSMGIMHRDVKPHNVMIDHENKKLRLIDWGLAEFY 1026
Query: 281 APSSRRTTLCGTLDYLPPE-MIEGRMHDEKVDLWSLGVLCYEFLVGKPP 328
P + + PE +++ +M+D +D+WSLG + + K P
Sbjct: 1027HPGMEYNVRVASRYFKGPELLLDYQMYDYSLDMWSLGCMFASMIFRKEP 1173
>26009
Length = 886
Score = 40.8 bits (94), Expect(2) = 3e-09, Method: Compositional matrix adjust.
Identities = 17/49 (34%), Positives = 30/49 (61%)
Frame = +3
Query: 216 GTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLL 264
GT ++ + + + +L +AL + HSK+++HRDIKPEN+L+
Sbjct: 666 GTCLTPSRRNKACGSREAKSVMKQLVSALDFMHSKQLVHRDIKPENVLI 812
Score = 38.1 bits (87), Expect(2) = 3e-09, Method: Compositional matrix adjust.
Identities = 26/91 (28%), Positives = 47/91 (51%), Gaps = 2/91 (2%)
Frame = +2
Query: 131 EDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLR- 189
E +++ + LG+G +G V LAR + + +ALK+L K+ + + +RE ++ L
Sbjct: 416 EHYDVCKELGRGTYGKVVLARCRHTGTQVALKLLPKSCTKL----REFQREFQLSYFLSP 583
Query: 190 HPNILRLYGY-FHDATRVYLILEYAPLGTVY 219
H NI+ Y F + E+A LG ++
Sbjct: 584 HANIIDTYNVAFQTRSSYVFAQEHAVLGDLF 676
>12786
Length = 460
Score = 58.9 bits (141), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 37/127 (29%), Positives = 54/127 (42%), Gaps = 24/127 (18%)
Frame = -3
Query: 228 FDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRT 287
D Y E+ A+ H++ VIH D+KP N +L AG LK+ DFG + + +
Sbjct: 419 LDRMMIKFYWREMLRAVKALHNEGVIHSDLKPANFML-VAGNLKLIDFGIANTLQQDKTS 243
Query: 288 TL----CGTLDYLPPEMIEGRMHDE--------------------KVDLWSLGVLCYEFL 323
L GT Y+ PE I D + D+WSLG + Y +
Sbjct: 242 VLKDSRVGTPSYMSPEAIMAACDDSADDSMEEDGHRTKPKYKVGVRSDVWSLGCILYNMV 63
Query: 324 VGKPPFE 330
G+ PF+
Sbjct: 62 YGRTPFQ 42
>18663
Length = 600
Score = 57.8 bits (138), Expect = 7e-09, Method: Compositional matrix adjust.
Identities = 32/112 (28%), Positives = 52/112 (46%), Gaps = 15/112 (13%)
Frame = +2
Query: 287 TTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEA---------NTYQET 337
+T CGT +Y+ PE++ G + VD W+LGVL YE L G+ PF+ NT
Sbjct: 2 STFCGTPNYIAPEILRGEDYGFSVDWWALGVLLYEMLAGRSPFDIAGASENPDQNTEDYL 181
Query: 338 YKRISRVEFTFPDFVTEGARDLISRLLKHNPSQR------PMLREVLEHPWI 383
++ I P ++ A ++ L NP+ R +++ HP+
Sbjct: 182 FQVILEKTIRIPRSLSVKAASVLKGFLNKNPADRLGCHRESAFMDIVNHPFF 337
>28638
Length = 1458
Score = 55.8 bits (133), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 41/132 (31%), Positives = 60/132 (45%), Gaps = 5/132 (3%)
Frame = -1
Query: 203 ATRVYLILEYAP-LGTVYRELQKLSKFDEQRTATYITELANALSYCHS--KRVIHRDIKP 259
AT L +P + T Q L T + +L AL + + +IH D+KP
Sbjct: 924 ATTCVWCLSCSPTISTTCYATQTLEGVSLNLTRKFAQQLCTALLFLATPEMNIIHCDLKP 745
Query: 260 ENLLLGSA--GELKIADFGWSVHAPSSRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGV 317
EN+LL + +KI DFG S R + Y PE++ G +D +D+WSLG
Sbjct: 744 ENILLCNPKRSAIKIVDFGSSCQL-GQRIYQYIQSRFYRSPEVLLGVPYDLAIDMWSLGC 568
Query: 318 LCYEFLVGKPPF 329
+ E G+PP
Sbjct: 567 ILVEMHTGEPPL 532
>02638
Length = 1490
Score = 53.1 bits (126), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 27/104 (25%), Positives = 52/104 (50%), Gaps = 5/104 (4%)
Frame = +1
Query: 289 LCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFT- 347
L GT+ ++ PE++ G + D+WS+G + E +PP+ ++ I ++ +
Sbjct: 16 LLGTIAFMAPEVLRGESYGRACDVWSVGCVMIEMCTCRPPWNSHDISNHLALIFKIASSV 195
Query: 348 ----FPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANS 387
P+ ++ RDL+ R L+ + RP +++L HP T S
Sbjct: 196 DPPPIPENMSPPVRDLMLRCLEQDSDFRPSAKDLLMHPLFTKYS 327
>11185
Length = 473
Score = 52.4 bits (124), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 30/110 (27%), Positives = 48/110 (43%), Gaps = 24/110 (21%)
Frame = +1
Query: 240 LANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFG----------------------W 277
L L Y HS ++ D++P +LL ++G LK ADFG W
Sbjct: 28 LVTGLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQW 207
Query: 278 SVHAPSS--RRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVG 325
++ + ++ G+ Y+ PE+ +G DLW+LG + YE G
Sbjct: 208 NIQSAEEMMKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSG 357
>25019
Length = 730
Score = 52.4 bits (124), Expect = 4e-07, Method: Compositional matrix adjust.
Identities = 25/59 (42%), Positives = 35/59 (59%), Gaps = 2/59 (3%)
Frame = +3
Query: 260 ENLLLGSAGELKIADFGWSVHAPSSRRTT--LCGTLDYLPPEMIEGRMHDEKVDLWSLG 316
EN+LL G +K+ DFG A + R T CGT++Y+ PE++ H + VD WSLG
Sbjct: 261 ENVLLDKDGHVKLTDFGLCKEAITGTRVTHTFCGTIEYMAPEILTRTGHGKAVDWWSLG 437
>29590
Length = 320
Score = 38.9 bits (89), Expect(2) = 1e-06, Method: Composition-based stats.
Identities = 17/41 (41%), Positives = 24/41 (58%)
Frame = +3
Query: 289 LCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPF 329
+ GT DY+ PE+++ + D+WSLGVL Y L PF
Sbjct: 54 IIGTPDYVAPEVLDYEPLSIQTDMWSLGVLSYVMLTACSPF 176
Score = 31.2 bits (69), Expect(2) = 1e-06, Method: Composition-based stats.
Identities = 16/41 (39%), Positives = 24/41 (58%), Gaps = 4/41 (9%)
Frame = +2
Query: 335 QETYKRISRVEFTFPD----FVTEGARDLISRLLKHNPSQR 371
QET+ IS+V+ FPD ++ A+D I +LL +P R
Sbjct: 191 QETFCNISQVKLDFPDDLFSHISPHAKDFIKKLLVKDPRHR 313
>27274
Length = 396
Score = 49.7 bits (117), Expect = 2e-06, Method: Composition-based stats.
Identities = 30/97 (30%), Positives = 45/97 (46%), Gaps = 12/97 (12%)
Frame = -1
Query: 299 EMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEAN------------TYQETYKRISRVEF 346
E++ G+ H VD+WSLG+L +E L G PFE Y + + SR
Sbjct: 375 ELLRGQQHGPTVDMWSLGILLHELLSGHVPFEPERGSRQMARNMMAVYAQIIRGSSRDVC 196
Query: 347 TFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWI 383
T GA D + RL++ ++R ++ HPWI
Sbjct: 195 DGLALSTHGA-DFLRRLVQLEDTKRLTSQQAFSHPWI 88
>31120
Length = 439
Score = 48.9 bits (115), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 33/99 (33%), Positives = 53/99 (53%), Gaps = 6/99 (6%)
Frame = +1
Query: 299 EMIEGRMHDEKV-DLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTF----PDFVT 353
E++ G +D K+ D WSLGV+ + L GK PF+ + + + +++F D V+
Sbjct: 1 EVVCGVPYDPKMADAWSLGVILFIMLNGKMPFDDSNLNKLLEDQRSKKYSFRRKLQDLVS 180
Query: 354 EGARDLISRLLKHNPSQRPMLREVLEHPWI-TANSSKPS 391
AR +S LL+ N + R L EVL W+ T + +PS
Sbjct: 181 PNARSTVSVLLEPNSAMRWDLNEVLNCQWLQTIDEPRPS 297
>37602
Length = 804
Score = 48.5 bits (114), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 32/99 (32%), Positives = 46/99 (46%), Gaps = 3/99 (3%)
Frame = -1
Query: 189 RHPNILRLYGYFHDATR---VYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALS 245
R NI GYF R +++ +EY G++ E + A E L
Sbjct: 354 RIVNIQTFVGYFDSYLRREKLWIAMEYCGGGSMQDIYHVTGPLTEPQIAFVCRETLKGLH 175
Query: 246 YCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSS 284
Y H + +HRDIK N+LL G++K+ADF W V + S
Sbjct: 174 YLHRRGKMHRDIKGANILLTEEGDVKLADF-WRVSSNHS 61
>07833
Length = 1504
Score = 48.1 bits (113), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 45/213 (21%), Positives = 88/213 (41%), Gaps = 21/213 (9%)
Frame = -3
Query: 188 LRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKF--DEQRTATYITELANALS 245
HPN+L + + + LI ++ P G++Y L S D+ ++ + ++A +
Sbjct: 1448 FNHPNVLPVLACCNQPPNLVLISQFMPFGSLYNTLHGESGIVVDQNQSLRFAMDIARGME 1269
Query: 246 YCHSKRVIHRDIKPE--NLLLGS---------AGELKIADFGWSVHAPSSRRTTLCGTLD 294
+ HS ++P N LL S + +AD+ +S H +
Sbjct: 1268 FLHS-------MEPTIPNFLLTSKHVMIDEDLTARINMADYCFSFHEKGKVYSP-----A 1125
Query: 295 YLPPEMIEGRMHD---EKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISR--VEFTFP 349
++ PE ++ R D D+WS +L +E + PF + E +++ + + P
Sbjct: 1124 WMAPEALQRRPDDINTRAADMWSFAILMWELETREVPFAELSSMEVGMKVALEGLRISIP 945
Query: 350 DFVTEGARDLISRLLKHNPSQRP---MLREVLE 379
++ LI + P +RP M+ +LE
Sbjct: 944 PGISLHMSRLIKICMNEEPGKRPRFDMIIPILE 846
>32000
Length = 644
Score = 48.1 bits (113), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 39/148 (26%), Positives = 63/148 (42%), Gaps = 31/148 (20%)
Frame = -1
Query: 267 AGELKIADFGWS--VHAPSSRRTTLCGTLDYLPPEMIEG-RMHDEKVDLWSLGVLCYEFL 323
++KIADFG + P T TL Y PE++ G R + VD+WSLG + E +
Sbjct: 581 TAKMKIADFGLARVFGLPVRTYTHEVITLWYRAPEILLGCRFYSVPVDIWSLGCIFVEMM 402
Query: 324 VGKPPFEANTYQETYKRISRVEFT-----------FPDF-----------------VTEG 355
+ F ++ + RI R T PD+ +++
Sbjct: 401 TRRALFPGDSEIDQLYRIFRTLGTPDEKVWPGVSKLPDYKPTFPKWPLKNLETVVSLSKV 222
Query: 356 ARDLISRLLKHNPSQRPMLREVLEHPWI 383
DL+ R+L +NP++R R + HP+
Sbjct: 221 GLDLLKRMLTYNPNRRISARSAMRHPYF 138
>07291
Length = 833
Score = 47.8 bits (112), Expect = 8e-06, Method: Compositional matrix adjust.
Identities = 25/97 (25%), Positives = 50/97 (51%), Gaps = 6/97 (6%)
Frame = +1
Query: 239 ELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHA-PSSRRTT----LCGTL 293
++A+ ++Y +V+HR++ N ++ G L+++D+G + P S T +
Sbjct: 73 QIADGMAYLQEVKVVHRNLAARNCIVTEDGRLQLSDYGVTGSLFPQSYYTADDSPARDLV 252
Query: 294 DYLPPEMIEGRMHDEKVDLWSLGVLCYEFLV-GKPPF 329
++ PE I+ K D+W+ GV+ +E L G P+
Sbjct: 253 KWMAPETIDNFHFSSKSDVWAFGVVLWELLTRGITPY 363
>01106
Length = 878
Score = 46.6 bits (109), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 46/147 (31%), Positives = 70/147 (47%), Gaps = 15/147 (10%)
Frame = +3
Query: 133 FEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQ--LEKAGVEHQLRREVEIQSHLRH 190
+ + R LG G F V+L + K +ALKV+ AQ E A E +L + V +S +
Sbjct: 324 YHVIRKLGWGHFSTVWLCWDLTCKRFVALKVVKSAQHYTETALDEVKLLKCVR-ESDVAD 500
Query: 191 PNILRLYGYFHD-------ATRVYLILEYAPLGTVYRELQKLSKFDEQRTATY-----IT 238
P + D T V ++ E LG Y L+ + + + Q + I
Sbjct: 501 PARAKCVQLLDDFKISGVNGTHVAMVFEV--LG--YNLLKLIIRSNYQGIPIHNVKLIIR 668
Query: 239 ELANALSYCHSK-RVIHRDIKPENLLL 264
++ LSY H+K R+IH DIKPEN+L+
Sbjct: 669 QVLEGLSYMHAKCRIIHTDIKPENILI 749
>18481
Length = 437
Score = 44.7 bits (104), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 38/119 (31%), Positives = 57/119 (47%), Gaps = 7/119 (5%)
Frame = -1
Query: 167 AQLEKAGVEHQL-RREVEIQSHL-RHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQK 224
++E V+HQL E ++ + RHP + +Y Y + L++E LG EL
Sbjct: 395 VKIEAIDVKHQLLHYEAKVYEQIGRHPGLPTMYHYGTEKHFNALVME--LLGPSLEELFV 222
Query: 225 LSK--FDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLG---SAGELKIADFGWS 278
+ K F + +L + L + H K IHRD+KP+N L+G L I DFG S
Sbjct: 221 ICKRRFTLKTILMVSDQLLSRLEFIHQKCFIHRDLKPDNFLMGLGRHCHRLYIIDFGLS 45
>32957
Length = 645
Score = 44.7 bits (104), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 20/60 (33%), Positives = 32/60 (53%)
Frame = +3
Query: 275 FGWSVHAPSSRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTY 334
F V R T CGT +Y+ PE+ E + + ++VD W LG+L +E L + ++ Y
Sbjct: 3 FALCVEKSGGRTRTFCGTREYMAPEVHERKEYGKEVDWWGLGILLHELLAAQIKKHSSCY 182
>31489
Length = 329
Score = 43.9 bits (102), Expect = 1e-04, Method: Composition-based stats.
Identities = 23/88 (26%), Positives = 43/88 (48%), Gaps = 6/88 (6%)
Frame = +3
Query: 182 VEIQSHLRHPNI------LRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTAT 235
++I H +H NI L+ +HD ++++ + ++R + E+
Sbjct: 3 IKILKHFKHDNIISIREILKPKDSYHDFKDIHVVFDLME-SDLHRIIYSDQPLTEEHIRY 179
Query: 236 YITELANALSYCHSKRVIHRDIKPENLL 263
++ ++ L Y HS V+HRD+KP NLL
Sbjct: 180 FLYQILRGLKYIHSANVVHRDLKPSNLL 263
>16708
Length = 1397
Score = 43.9 bits (102), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 64/266 (24%), Positives = 100/266 (37%), Gaps = 33/266 (12%)
Frame = -1
Query: 139 LGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNIL-RLY 197
LGKG FG VY AR L KA L+ + + H EVE + L +++
Sbjct: 1379 LGKGVFGKVYEAR--------LLSTHEKAALKTSILCHHSLDEVEALGRIEGGFYLAQMF 1224
Query: 198 GY------FHDATRVYLILEYAPLGTVYRELQK----LSKFDEQRTATYITELANALSYC 247
G F + E PL VY + + + + AL +
Sbjct: 1223 GAWVTCLPFPKMNILLHFYEMGPLCNVYAHYKNKEMPIRWSNPAMVCCIAGQXVCALEHI 1044
Query: 248 HSKRVIHRDIKPENLLLGSAGELKIADFG----WSVH-APSSRRTTLCG---TLDYLPPE 299
H V+H D+K +N+L+ + G K+ D+G + V+ AP+ ++ C T PP
Sbjct: 1043 HELGVVHMDVKADNVLVDAHGNCKLTDYGIAQLYKVYPAPTETHSSGCTNKRTFYTRPPA 864
Query: 300 -MIEGRMHDEKVD------------LWSL-GVLCYEFLVGKPPFEANTYQETYKRISRVE 345
M E+ D LW+L G + V +PP + + R E
Sbjct: 863 TMTPSERFSEEGDGIGTDYFRLGQMLWTLTGAVLLHVWVSRPPKLPD-----WCRTPESE 699
Query: 346 FTFPDFVTEGARDLISRLLKHNPSQR 371
+ G D I +L +P+ R
Sbjct: 698 LS-------GMSDFIEKLCHGDPNMR 642
>17253
Length = 483
Score = 43.9 bits (102), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 27/112 (24%), Positives = 53/112 (47%), Gaps = 13/112 (11%)
Frame = -1
Query: 180 REVEIQSHL-RHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQK--------LSKFDE 230
RE+ I L RHPN++ G + +++E+ G + L+K L+
Sbjct: 402 RELSIMRKLPRHPNVVSFMGCCTMSDPALILMEFCCHGDLLSFLRKRRPDRTVFLTSTAN 223
Query: 231 QRTA----TYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS 278
TA ++ +A +++ + +++HRD+ N+L+ K++DFG S
Sbjct: 222 DLTARDFFSFALHVARGMAHVANNKIVHRDVAARNVLISERNVCKVSDFGLS 67
>20640
Length = 1492
Score = 43.5 bits (101), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 38/144 (26%), Positives = 65/144 (45%), Gaps = 5/144 (3%)
Frame = +1
Query: 253 IHRDIKPENLLLGSAGELKIADFGW--SVHAPSSRRTTLCGT--LDYLPPEMIEGRMHDE 308
+HRD+ N L+G +KI+DFG SVH+ R + + ++P E I
Sbjct: 10 VHRDLATRNCLVGHDLVVKISDFGLARSVHSVDYYRGSEHDAIPIRWMPLEAILYNKFST 189
Query: 309 KVDLWSLGVLCYE-FLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHN 367
+ D+WS GV+ +E F P+ T++E + FV EG ++L
Sbjct: 190 QSDVWSFGVVLWEIFAFALQPYYGLTHEEVVR-----------FVKEG------KVLACP 318
Query: 368 PSQRPMLREVLEHPWITANSSKPS 391
P + E+++ W +++PS
Sbjct: 319 ERTPPPMYELMKQCWHRRPATRPS 390
>07836
Length = 1478
Score = 42.7 bits (99), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 49/195 (25%), Positives = 85/195 (43%), Gaps = 31/195 (15%)
Frame = -1
Query: 159 LALKVLFKAQLEKAGVEHQLRREVEIQSH--LRHPNILRLYGY----FHDATRVYLILEY 212
+A+K+ F + E RE E+ LRH NIL T+++LI +Y
Sbjct: 1469 VAVKIFFTTE------EASWFRETELYQTVLLRHENILGFIAADIKGTGSWTQLFLITDY 1308
Query: 213 APLGTVYRELQKLSK-FDEQRTATYITELANALSYCHSK--------RVIHRDIKPENLL 263
G+++ L LS+ D L++ H + + HRDIK +N+L
Sbjct: 1307 HENGSLHDYL--LSRVLDSSEMLALAHSAICGLAHLHIEIFGTRGKPAIAHRDIKSKNIL 1134
Query: 264 LGSAGELKIADFGWSVH----------APSSRRTTLCGTLDYLPPEMIEGRMHD------ 307
+ G IAD G +V AP+ R+ GT Y+ PE++E ++
Sbjct: 1133 VKKNGTCCIADLGLAVRYISESNEVDVAPNPRQ----GTKRYMAPEVLEMLLNVKNFDAF 966
Query: 308 EKVDLWSLGVLCYEF 322
++ D+++ G++ +E
Sbjct: 965 KQADMYAFGLVMWEI 921
>20559
Length = 430
Score = 39.7 bits (91), Expect(2) = 3e-04, Method: Compositional matrix adjust.
Identities = 22/81 (27%), Positives = 45/81 (55%)
Frame = -2
Query: 130 LEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLR 189
++ +E +G+G +G V+ A+ +++ I+ALK + + + GV RE+ + L+
Sbjct: 378 MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRV-RLDDDDEGVPSSALREICLLKELK 202
Query: 190 HPNILRLYGYFHDATRVYLIL 210
H NI+RL+ H ++ L+
Sbjct: 201 HRNIVRLHDVLHSERKLTLVF 139
Score = 21.9 bits (45), Expect(2) = 3e-04, Method: Compositional matrix adjust.
Identities = 7/12 (58%), Positives = 9/12 (75%)
Frame = -1
Query: 244 LSYCHSKRVIHR 255
L +CHS V+HR
Sbjct: 37 LVFCHSNNVLHR 2
>17300
Length = 480
Score = 42.0 bits (97), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 29/98 (29%), Positives = 46/98 (46%), Gaps = 7/98 (7%)
Frame = +1
Query: 253 IHRDIKPENLLLGSAGELKIADFGWSVHAPSSRR----TTLCGTL--DYLPPEMIEGRMH 306
+HRD+ N+L+ K+ADFG S S TT G + + PE I R
Sbjct: 40 VHRDLAARNILVNEILVCKVADFGLSREIESDTTEGAYTTKGGKIPVRWTAPEAIAYRKF 219
Query: 307 DEKVDLWSLGVLCYEFL-VGKPPFEANTYQETYKRISR 343
D+WS GV+ +E + G+ P+ + Q+ K + +
Sbjct: 220 TSASDVWSFGVVMWEVMSYGERPYWNWSNQDVIKAVEK 333
>11404
Length = 563
Score = 40.8 bits (94), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 42/150 (28%), Positives = 71/150 (47%), Gaps = 12/150 (8%)
Frame = +1
Query: 127 QWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKV-------LFKAQLEKAGVEHQLR 179
+WA + +EI +GKG FG V A + +A+K+ L +AQ+E +E R
Sbjct: 130 KWA-DRYEIDSLIGKGSFGQVVKAYDHTDNEQVAIKIIKNKKPFLNQAQIEVKLLEMMNR 306
Query: 180 REVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKF---DEQRTATY 236
+ + + + I+RL +F R +L L + L +L + + F T +
Sbjct: 307 HDTDNKYY-----IVRLKRHF--MFRSHLCLVFELLSYNLYDLLRNTNFRGVSLNLTRKF 465
Query: 237 ITELANALSYCHS--KRVIHRDIKPENLLL 264
+L AL + + +IH D+KPEN+LL
Sbjct: 466 AQQLCTALLFLATPEMSIIHCDLKPENILL 555
>21210
Length = 518
Score = 40.4 bits (93), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 27/106 (25%), Positives = 49/106 (46%), Gaps = 13/106 (12%)
Frame = +3
Query: 291 GTLDYLPPEMIEGRM----HDEKVDLWSLGVLCYEFLVGKPPFE--ANTYQETYKRISRV 344
G Y+ PE I+ R +D + D+WSLG+ E G+ P+ + + + + + V
Sbjct: 6 GCRPYMAPERIDPRASSHGYDVRSDVWSLGITLMELATGRFPYRKWVSIFDQLQQVVRGV 185
Query: 345 EFTFP-------DFVTEGARDLISRLLKHNPSQRPMLREVLEHPWI 383
P DFV + +++ L + QRP ++L HP++
Sbjct: 186 APCLPHDGAFSHDFV-----NFVNKCLTKDEKQRPKYNKLLAHPFV 308
>21418
Length = 831
Score = 39.7 bits (91), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 20/56 (35%), Positives = 32/56 (57%), Gaps = 4/56 (7%)
Frame = +2
Query: 339 KRISRVEFTFPD----FVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKP 390
KRI ++ FPD V++ A+DLI +L +PS+R + +VL + WI + P
Sbjct: 8 KRIRSGQYDFPDPEWTNVSQAAKDLIKGMLNVDPSKRLCIEDVLRNKWIAQYDAVP 175
>20160
Length = 1277
Score = 38.5 bits (88), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 15/33 (45%), Positives = 24/33 (72%)
Frame = +2
Query: 354 EGARDLISRLLKHNPSQRPMLREVLEHPWITAN 386
E A DLI+R + +PS RP+L ++L+H W+T +
Sbjct: 332 EDAADLINRCIALDPSTRPVLADILKHKWMTKD 430
>00638
Length = 1595
Score = 38.1 bits (87), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 15/37 (40%), Positives = 21/37 (56%)
Frame = +2
Query: 223 QKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKP 259
Q F + Y+ EL AL +CHS ++HRD+KP
Sbjct: 392 QLYQTFTDYDIRFYLYELMKALDFCHSMGIMHRDVKP 502
>31789
Length = 676
Score = 36.6 bits (83), Expect = 0.018, Method: Compositional matrix adjust.
Identities = 27/103 (26%), Positives = 45/103 (43%), Gaps = 5/103 (4%)
Frame = +2
Query: 132 DFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHP 191
D EIGR G F VY + + +A L + K + + E E+ L+HP
Sbjct: 335 DVEIGR----GSFKTVYKGLDTELGVAVAWCELQDKKWNKT-ERQRFKEEAEMLKELQHP 499
Query: 192 NILRLYGYFHDATR-----VYLILEYAPLGTVYRELQKLSKFD 229
NI+R + Y+ + + L+ E GT+ L++ K +
Sbjct: 500 NIVRFFDYWEEHNHRNRKVIILVTELMTSGTLKTYLKRFKKIN 628
>36002
Length = 253
Score = 36.2 bits (82), Expect = 0.023, Method: Compositional matrix adjust.
Identities = 21/66 (31%), Positives = 31/66 (46%), Gaps = 5/66 (7%)
Frame = +1
Query: 324 VGKPPFEANTYQET-YKRISRVEFTFPDF----VTEGARDLISRLLKHNPSQRPMLREVL 378
V +P QE + RI + FP ++ A+DLI LL P +R +VL
Sbjct: 16 VAEPGEACQDCQELLFNRIQDGNYFFPSMEWSAISSSAKDLIRHLLVREPRKRYSAADVL 195
Query: 379 EHPWIT 384
+HPW+
Sbjct: 196 KHPWVC 213
>37063
Length = 455
Score = 35.4 bits (80), Expect = 0.043, Method: Compositional matrix adjust.
Identities = 23/77 (29%), Positives = 41/77 (53%), Gaps = 15/77 (19%)
Frame = -2
Query: 257 IKPENLLLGSAGE---LKIADF----GWSVHAPSSRRTTL---CGTLDYLPPEMIEGRM- 305
+KPEN+L E LKI DF G + ++ L G+ +Y+ PE+++ +
Sbjct: 454 LKPENILCEHLDEVVPLKICDFDLASGINCDGDGTKTPELLTPVGSAEYMAPEVVDAWVG 275
Query: 306 ----HDEKVDLWSLGVL 318
+D++ D+WSLG++
Sbjct: 274 ESFSYDKRCDMWSLGII 224
>20655
Length = 1181
Score = 34.7 bits (78), Expect = 0.068, Method: Compositional matrix adjust.
Identities = 17/56 (30%), Positives = 31/56 (55%), Gaps = 4/56 (7%)
Frame = +2
Query: 339 KRISRVEFTFP----DFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKP 390
KRI ++ FP V++ A+DLI +L +P +R +++V+ W+ N+ P
Sbjct: 8 KRIRNGQYEFPKPEWSRVSQDAKDLIRGMLCTDPDKRLNIKQVMASKWVADNTMVP 175
>00394
Length = 548
Score = 34.7 bits (78), Expect = 0.079, Method: Compositional matrix adjust.
Identities = 23/94 (24%), Positives = 43/94 (45%), Gaps = 5/94 (5%)
Frame = -2
Query: 137 RPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRL 196
+ +G+G F VY + + +A L + KA + + E E+ L+HPNI+R
Sbjct: 280 KEIGRGSFKTVYKGLDTELGVAVAWCELQDKKWNKAE-RQRFKEEAEMLKELQHPNIVRF 104
Query: 197 YGYFHDATR-----VYLILEYAPLGTVYRELQKL 225
+ Y+ + + L+ E GT+ L++
Sbjct: 103 FDYWEEHNHRNRKVIILVTELMTSGTLKTYLKRF 2
>18401
Length = 463
Score = 32.7 bits (73), Expect = 0.26, Method: Compositional matrix adjust.
Identities = 16/63 (25%), Positives = 29/63 (46%)
Frame = -3
Query: 287 TTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEF 346
+T+ T Y PE+I D+WS+G + +E G F+ + +E + R+
Sbjct: 458 STIVSTRHYRAPEVILELGWSHPCDVWSVGCIMFELYTGYTLFQTHDNKEHLAMMERILG 279
Query: 347 TFP 349
+ P
Sbjct: 278 SLP 270
>20773
Length = 391
Score = 32.0 bits (71), Expect = 0.48, Method: Compositional matrix adjust.
Identities = 17/54 (31%), Positives = 28/54 (51%)
Frame = -1
Query: 330 EANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWI 383
+ + ++R SR F VT+ +L+ RLL ++PSQR L HP++
Sbjct: 388 SGSCWSGLHRRRSRPVFPHTTVVTQHFYNLVQRLLTYDPSQRLTPDLALSHPFV 227
>21800
Length = 855
Score = 32.0 bits (71), Expect = 0.49, Method: Compositional matrix adjust.
Identities = 17/46 (36%), Positives = 26/46 (56%), Gaps = 5/46 (10%)
Frame = +2
Query: 237 ITELANALSYCHSK-RVIHRDIKPENLLLGSAG----ELKIADFGW 277
I ++ L+Y H+K +IH DIKPEN+L+ +L + F W
Sbjct: 650 IRQVLEGLNYLHAKCNIIHTDIKPENILICVDDNYIRKLAVDAFEW 787
>36481
Length = 806
Score = 32.0 bits (71), Expect = 0.51, Method: Compositional matrix adjust.
Identities = 32/141 (22%), Positives = 65/141 (46%), Gaps = 8/141 (5%)
Frame = +2
Query: 132 DFEIGRPLGKGKFGNVYLAREKQSKFILALKVL--FKAQLEKAGVE-HQLRREVEIQSHL 188
D ++ G+G FG V ++ +ALK++ E A +E + L + E H
Sbjct: 365 DMKLCPHWGEGTFGKVVQCKDLLKGDDIALKIIKNVDKYREAAKLEINVLEKLREKDPHA 544
Query: 189 RHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKF-----DEQRTATYITELANA 243
+H + L + + ++ + + LG + K + + ++ R +Y +L A
Sbjct: 545 KHMCVQMLDWFDYHG---HVCISFHMLGLSVFDFLKDNSYGAYPIEQVRHISY--QLCYA 709
Query: 244 LSYCHSKRVIHRDIKPENLLL 264
+++ H ++ H D+KPEN+L
Sbjct: 710 VNFLHENQLTHTDLKPENILF 772
>19872
Length = 446
Score = 31.6 bits (70), Expect = 0.53, Method: Compositional matrix adjust.
Identities = 14/41 (34%), Positives = 25/41 (60%), Gaps = 4/41 (9%)
Frame = +3
Query: 349 PDFVTEGA----RDLISRLLKHNPSQRPMLREVLEHPWITA 385
PDF + L+ ++L H+P+QRP R++L+ P++ A
Sbjct: 99 PDFTKDADLHNQSALLRQMLSHDPTQRPSSRDLLQSPYLPA 221
>17932
Length = 597
Score = 28.1 bits (61), Expect(2) = 0.76, Method: Compositional matrix adjust.
Identities = 14/31 (45%), Positives = 16/31 (51%), Gaps = 2/31 (6%)
Frame = -2
Query: 313 WSLGVLCYEFLVGKPPF--EANTYQETYKRI 341
WSLGV YE L G PF + + TY I
Sbjct: 593 WSLGVCAYEMLFGCTPFTDDDGSMVATYNNI 501
Score = 21.6 bits (44), Expect(2) = 0.76, Method: Compositional matrix adjust.
Identities = 14/32 (43%), Positives = 20/32 (62%)
Frame = -3
Query: 352 VTEGARDLISRLLKHNPSQRPMLREVLEHPWI 383
V++ ARDLIS+LL S R E+ +HP+
Sbjct: 460 VSKEARDLISQLLSDGKS-RLGWPELQQHPFF 368
>16350
Length = 1108
Score = 29.6 bits (65), Expect = 2.1, Method: Compositional matrix adjust.
Identities = 12/39 (30%), Positives = 23/39 (58%), Gaps = 1/39 (2%)
Frame = +3
Query: 358 DLISRLLKHNPSQRPMLREVLEHPWITANS-SKPSNCQN 395
D ++ +L+ +P QR + L+HPW+ ++ +PS Q
Sbjct: 762 DFLAPMLEFDPEQRATAAQSLQHPWLKLDA*PEPSGSQQ 878
>20513
Length = 405
Score = 29.3 bits (64), Expect = 2.9, Method: Compositional matrix adjust.
Identities = 12/39 (30%), Positives = 23/39 (58%), Gaps = 1/39 (2%)
Frame = -1
Query: 358 DLISRLLKHNPSQRPMLREVLEHPWITANS-SKPSNCQN 395
D ++ +L+ +P QR + L+HPW+ ++ +PS Q
Sbjct: 282 DFLAPMLEFDPEQRATAAQSLQHPWLKLDA*PEPSGSQQ 166
>17644
Length = 463
Score = 27.7 bits (60), Expect = 8.1, Method: Compositional matrix adjust.
Identities = 13/32 (40%), Positives = 19/32 (59%)
Frame = +3
Query: 352 VTEGARDLISRLLKHNPSQRPMLREVLEHPWI 383
VT+ BL+ RLL ++PSQR L HP++
Sbjct: 69 VTQHFYBLVQRLLTYDPSQRLTPDLALSHPFV 164
>18929
Length = 440
Score = 27.7 bits (60), Expect = 9.8, Method: Compositional matrix adjust.
Identities = 11/38 (28%), Positives = 22/38 (57%)
Frame = +1
Query: 348 FPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITA 385
F + ++ + +I R++ +P QRP ++L HP + A
Sbjct: 34 FINTISVELQQVIRRMMSPDPRQRPTANQLLAHPTLAA 147
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000379250 | hsapiens_gene_ensembl |
Serine/threonine-protein kinase 6 (EC 2.7.11.1) (Aurora kinase A)
(Aurora-A) (Serine/threonine kinase 15) (Aurora/IPL1-related kinase 1)
(Aurora-related kinase 1) (hARK1) (Breast-tumor-amplified kinase).
[Source:Uniprot/SWISSPROT;Acc:O14965]
(403 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
21433 184 3e-69
15910 120 8e-28
03240 119 2e-27
01060 117 6e-27
00300 114 8e-26
30755 110 1e-24
18484 110 1e-24
18921 107 7e-24
12721 105 4e-23
14420 101 5e-22
01707 99 3e-21
14126 98 5e-21
09606 97 8e-21
06405 97 9e-21
09007 94 8e-20
13592 93 2e-19
13212 92 3e-19
01392 91 1e-18
01756 87 1e-17
13066 87 1e-17
11780 80 2e-17
04591 86 2e-17
01718 86 3e-17
17975 85 4e-17
31885 84 7e-17
27546 83 2e-16
00486 82 3e-16
21079 82 6e-16
00392 80 1e-15
01966 79 3e-15
19761 76 2e-14
19094 70 6e-14
26560 75 7e-14
29581 72 4e-13
20152 69 3e-12
27405 68 7e-12
26711 66 3e-11
19301 65 5e-11
38560 65 6e-11
14477 64 1e-10
04852 64 1e-10
06358 64 1e-10
04138 64 2e-10
21808 63 2e-10
00715 62 5e-10
14116 61 6e-10
28157 61 8e-10
12672 61 9e-10
07940 61 1e-09
03508 61 1e-09
26009 41 3e-09
12786 59 3e-09
18663 58 7e-09
28638 56 3e-08
02638 53 2e-07
11185 52 3e-07
25019 52 4e-07
29590 39 1e-06
27274 50 2e-06
31120 49 4e-06
37602 49 4e-06
07833 48 6e-06
32000 48 6e-06
07291 48 8e-06
01106 47 2e-05
18481 45 6e-05
32957 45 6e-05
31489 44 1e-04
16708 44 1e-04
17253 44 1e-04
20640 44 1e-04
07836 43 3e-04
20559 40 3e-04
17300 42 4e-04
11404 41 0.001
21210 40 0.001
21418 40 0.002
20160 39 0.006
00638 38 0.006
31789 37 0.018
36002 36 0.023
37063 35 0.043
20655 35 0.068
00394 35 0.079
18401 33 0.26
20773 32 0.48
21800 32 0.49
36481 32 0.51
19872 32 0.53
17932 28 0.76
16350 30 2.1
20513 29 2.9
17644 28 8.1
18929 28 9.8
>21433
Length = 590
Score = 184 bits (467), Expect(2) = 3e-69, Method: Compositional matrix adjust.
Identities = 93/136 (68%), Positives = 107/136 (78%)
Frame = +2
Query: 231 QRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLC 290
+RTA YI +L++AL YCH ++VIHRDIKPENLLLG G+LKIADFGWSVHAPSSRRTT+C
Sbjct: 167 KRTACYIYQLSSALEYCHYRKVIHRDIKPENLLLGLKGDLKIADFGWSVHAPSSRRTTMC 346
Query: 291 GTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPD 350
GTLDYLPPEM+EG+ HDE VDLWSLGVLCYEFLVG PP + + R P
Sbjct: 347 GTLDYLPPEMVEGKTHDENVDLWSLGVLCYEFLVGTPPLRPSPTRPPTPASPRWTSGSPS 526
Query: 351 FVTEGARDLISRLLKH 366
VT GARDLIS+LL+H
Sbjct: 527 IVTPGARDLISKLLRH 574
Score = 95.9 bits (237), Expect(2) = 3e-69, Method: Compositional matrix adjust.
Identities = 44/64 (68%), Positives = 54/64 (84%), Gaps = 1/64 (1%)
Frame = +3
Query: 176 HQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDE-QRTA 234
HQLRRE+EIQSHLRH NILR++GYFHD TRVYLILE+AP G +Y+ELQ+ KFDE ++ A
Sbjct: 3 HQLRREIEIQSHLRHDNILRMFGYFHDKTRVYLILEFAPKGELYKELQRCHKFDENEQHA 182
Query: 235 TYIT 238
Y +
Sbjct: 183 IYTS 194
>15910
Length = 1361
Score = 120 bits (302), Expect = 8e-28, Method: Compositional matrix adjust.
Identities = 61/177 (34%), Positives = 104/177 (58%), Gaps = 8/177 (4%)
Frame = +2
Query: 226 SKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLL---LGSAGELKIADFGWS-VHA 281
++ E+ A I+++ + + Y H+ V+HRD+KPENLL + +LK+ADFG S +
Sbjct: 449 GQYTEKDAARAISDILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLADFGLSRIIE 628
Query: 282 PSSRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRI 341
P + +T+CGT Y PE+++G + VD+WS+GV+ Y L G PF A E Y++I
Sbjct: 629 PEVQMSTVCGTPGYCAPEVLKGDKYTPSVDMWSVGVIAYILLCGYEPFFAENEFEMYRKI 808
Query: 342 SRVEFTFPD----FVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQ 394
+ E+ F + ++E A+D++ +LL +P +R E L PW+ ++K +N +
Sbjct: 809 IKGEYKFDEEYWSEISENAKDVVRKLLVIDPKKRLTATEALRLPWVKGVATKTTNME 979
>03240
Length = 1683
Score = 119 bits (298), Expect = 2e-27, Method: Compositional matrix adjust.
Identities = 86/283 (30%), Positives = 133/283 (46%), Gaps = 52/283 (18%)
Frame = -3
Query: 133 FEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPN 192
FE + LG G FG V L R+ + + A+K L K+ + K ++ E +I + +
Sbjct: 1285 FEKIKTLGVGAFGEVSLCRKNDTGMLYAMKTLRKSDVLKRNQVAHVKAERDILAEADNEW 1106
Query: 193 ILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRV 252
+++LY F D +Y +++Y P G + L ++ DE Y+ EL A+ H
Sbjct: 1105 VVKLYYSFQDHNYLYFVMDYVPGGDLMGLLIRMEILDEPLARFYVAELVQAIESVHRMGF 926
Query: 253 IHRDIKPENLLLGSAGELKIADFG------WS----------VHA--------------- 281
IHRDIKP+N+L+ G +K+ DFG W+ HA
Sbjct: 925 IHRDIKPDNILIDRNGHIKLTDFGLCTGFRWTHNSKYYQRDGTHARQDSMEVKCQLDEQC 746
Query: 282 ------PSSRRT---------TLCGTLDYLPPEMIEGRM--HDEKVDLWSLGVLCYEFLV 324
P RR +L GT +Y+ PE++ R+ + D WS+GV+ +E LV
Sbjct: 745 QCEILKPLERRRKREQRCLAHSLVGTPNYIAPEVL-SRLGGYTSVCDWWSVGVILFEMLV 569
Query: 325 GKPPFEANTYQET-YKRIS---RVEFTFPDFVTEGARDLISRL 363
G PPF ANT ET YK I+ ++ +++ A+DLI RL
Sbjct: 568 GHPPFYANTPAETQYKVINWKDMLKIPRESNLSQPAKDLILRL 440
>01060
Length = 1800
Score = 117 bits (294), Expect = 6e-27, Method: Compositional matrix adjust.
Identities = 83/305 (27%), Positives = 145/305 (47%), Gaps = 36/305 (11%)
Frame = +1
Query: 129 ALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHL 188
AL D + +G+G +G VY R + + LA+K + + + + GV RE+ + L
Sbjct: 67 ALSDLTDFQKIGEGTYGVVYKCRHRATGRKLAMKKI-RLRGSEDGVPSSAIREIAMLREL 243
Query: 189 RHPNILRLYGYFHDATRVYLILEY--APLGTVYRELQKLSKFDEQRTATYITELANALSY 246
RH NI+ L + R++L+ E+ L + + D + +Y+ ++ + +
Sbjct: 244 RHTNIVCLEDVIMEDERLFLVFEFLSMDLKMYIDKFPEGVVLDRRLVKSYVFQIVTGIXF 423
Query: 247 CHSKRVIHRDIKPENLLLGSAGELKIADFGW--SVHAPSSRRTTLCGTLDYLPPEMIEG- 303
CH +R++HRD+KP+NLL+ G +KIADFG + P T TL Y PE++ G
Sbjct: 424 CHQRRIVHRDLKPQNLLINHTGAIKIADFGMARTFALPVRAYTHEVVTLWYRAPEILMGA 603
Query: 304 RMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRV-----EFTFPDF------- 351
+ VD+WS+G + + L+ P F+ ++ + +I R+ E T+P+F
Sbjct: 604 SKYSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKLPAFN 783
Query: 352 -----------------VTEGARDLISRLLKHNPSQRPMLREVLEHPWI--TANSSKPSN 392
+ DLI R LK +P+QR +++L+H + S KP +
Sbjct: 784 GMFPLWKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYFLNVDTSVKPVD 963
Query: 393 CQNKE 397
+ E
Sbjct: 964 VPSPE 978
>00300
Length = 2318
Score = 114 bits (285), Expect = 8e-26, Method: Compositional matrix adjust.
Identities = 74/257 (28%), Positives = 125/257 (48%), Gaps = 10/257 (3%)
Frame = -1
Query: 136 GRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILR 195
G +G+G+FG VY A + ++ALK + K Q ++ E++I ++H N+++
Sbjct: 1643 GNKIGEGQFGKVYTAVNMSTGELMALKEM-KFQPNDLQQLREMCDEIKIFEGIQHENLVK 1467
Query: 196 LYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHR 255
YG + + +EY GT+ E K+ E Y E+ A+++ H ++HR
Sbjct: 1466 YYGVEVHKDEMLMFMEYCDTGTI-EEAAKMG-LPEYLIRRYTREIVLAVNHLHENSIVHR 1293
Query: 256 DIKPENLLLGSAGELKIADFGWSVHAPSSRRT-----TLCGTLDYLPPEMI---EGRMHD 307
DIK N+ L S G +K+ DFG SV S L GT Y+ PE+ + +
Sbjct: 1292 DIKGANIFLTSNGHVKLGDFGCSVKLKSHTTMPGEFHNLVGTTAYMAPEVFTQNDQGGYG 1113
Query: 308 EKVDLWSLGVLCYEFLVGKPPFE--ANTYQETYKRISRVEFTFPDFVTEGARDLISRLLK 365
D+WSLG + E GK P+ N YQ YK + PD ++ + + ++
Sbjct: 1112 RAADIWSLGCVVIEMATGKRPWHDLDNNYQIMYKVGIGHKPAVPDSLSVEGKHFLDLIMC 933
Query: 366 HNPSQRPMLREVLEHPW 382
H+P+QR + ++L+H +
Sbjct: 932 HDPAQRALASQLLDHTF 882
>30755
Length = 1137
Score = 110 bits (275), Expect = 1e-24, Method: Compositional matrix adjust.
Identities = 60/165 (36%), Positives = 91/165 (55%), Gaps = 7/165 (4%)
Frame = +2
Query: 228 FDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRT 287
F E+RT Y E+ +AL Y HS+ +I+RD+K ENLLL G +K+ADFG + RT
Sbjct: 23 FTEERTRFYGAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCKEDITYGRT 202
Query: 288 T--LCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVE 345
T CGT +YL PE+++ + VD W GV+ YE + G+ PF + + I +
Sbjct: 203 TKTFCGTPEYLAPEVLDDNDYGRAVDWWGTGVVMYEMICGRLPFYNRDHDVLFTLILVED 382
Query: 346 FTFPDFVTEGARDLISRLLKHNPSQR-----PMLREVLEHPWITA 385
FP +T+ A+ L+S LL +P R ++E+ HP+ +
Sbjct: 383 VKFPRNITDEAKSLLSGLLAKDPRNRLGGGQDDVKEIQAHPFFAS 517
>18484
Length = 635
Score = 110 bits (275), Expect = 1e-24, Method: Compositional matrix adjust.
Identities = 57/156 (36%), Positives = 89/156 (57%), Gaps = 2/156 (1%)
Frame = +1
Query: 218 VYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGW 277
+YR +Q+ KF E A Y E+A L + H + +I+RD+K +N++L S G +KIADFG
Sbjct: 7 MYR-IQQEGKFKEPVAAFYAAEIAVGLFFLHDQGIIYRDLKLDNVMLDSEGHIKIADFGM 183
Query: 278 SVHAPSSRRTT--LCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQ 335
+ TT CGT DY+ PE++ + + + VD W+ GVL +E L G+PPF+
Sbjct: 184 CKEGMTGDATTRTFCGTPDYIAPEIVLYQPYSKSVDWWAYGVLLFEMLAGQPPFDGEDED 363
Query: 336 ETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQR 371
E + I+ ++P ++ A L LL NP++R
Sbjct: 364 ELFSSITDHNVSYPKAMSREAVSLCKGLLMKNPTKR 471
>18921
Length = 697
Score = 107 bits (268), Expect = 7e-24, Method: Compositional matrix adjust.
Identities = 64/199 (32%), Positives = 109/199 (54%), Gaps = 3/199 (1%)
Frame = +2
Query: 133 FEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPN 192
F+I LG+G +G+V+ + K++ +LA+K Q+ ++ +E+ I
Sbjct: 35 FDILGKLGEGSYGSVFKSLHKETGQVLAIK-----QVPVDTDLQEIIKEISIMQQCDSKY 199
Query: 193 ILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSK-FDEQRTATYITELANALSYCHSKR 251
I++ YG + T +++++EY G+V ++ +K E+ AT + L Y HS+R
Sbjct: 200 IVKYYGSYFKNTDLWIVMEYCGAGSVSDIMRLRNKTLVEREIATILYYTLKGLXYLHSRR 379
Query: 252 VIHRDIKPENLLLGSAGELKIADFGWS--VHAPSSRRTTLCGTLDYLPPEMIEGRMHDEK 309
IHRDIK N+LL + G K+ADFG + + ++R T+ GT ++ PE+I+ +D
Sbjct: 380 KIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTPYWMAPEVIQEIGYDCV 559
Query: 310 VDLWSLGVLCYEFLVGKPP 328
D+WSLG+ E GKPP
Sbjct: 560 ADIWSLGITALEMAEGKPP 616
>12721
Length = 821
Score = 105 bits (261), Expect = 4e-23, Method: Compositional matrix adjust.
Identities = 69/247 (27%), Positives = 123/247 (49%), Gaps = 5/247 (2%)
Frame = +1
Query: 130 LEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLR 189
L+DF +G+G G V +A + + +A+K K L K L EV +
Sbjct: 94 LDDF---MKIGEGSTGIVCIATSRDGR-QMAVK---KMDLRKQQRRELLFNEVVVMRDYH 252
Query: 190 HPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHS 249
HPNI+ +Y + +++++E+ G ++ ++ DE + AT AL++ H+
Sbjct: 253 HPNIVEMYNSYLVNDELWVVMEFME-GGALTDIVTNNRMDEVQIATVCRACLKALAFLHA 429
Query: 250 KRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSS--RRTTLCGTLDYLPPEMIEGRMHD 307
VIHRDIK +++LL G++K+ DFG+ +R +L GT ++ PE+I +
Sbjct: 430 NGVIHRDIKSDSILLSHDGKVKLXDFGFCAQVTQDLQKRKSLVGTPYWMAPEVISRLPYG 609
Query: 308 EKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRV---EFTFPDFVTEGARDLISRLL 364
+VD+WSLG++ E + +PPF + +RI + + ++ + I R+L
Sbjct: 610 PEVDIWSLGIMVMEMIDAEPPFFNEPPLQAMRRIRDMPPPKLRNTHKISPRLQGFIDRML 789
Query: 365 KHNPSQR 371
+P QR
Sbjct: 790 VRDPHQR 810
>14420
Length = 528
Score = 101 bits (252), Expect = 5e-22, Method: Compositional matrix adjust.
Identities = 48/151 (31%), Positives = 87/151 (57%), Gaps = 2/151 (1%)
Frame = +2
Query: 181 EVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITEL 240
E+ + ++PNI+ + +++++E+ G++ + + + DE + A E
Sbjct: 50 EILVMRENQNPNIVNYLDSYLVGEELWVVMEFLAGGSLTDVVTE-TCMDEGQIAAVCREC 226
Query: 241 ANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAP--SSRRTTLCGTLDYLPP 298
AL + H +VIHRDIK +N+LLG G +K+ DFG+ S+R+T+ GT ++ P
Sbjct: 227 LQALEFLHENQVIHRDIKSDNILLGMDGSVKLTDFGFCAQLSPEQSKRSTMVGTPYWMAP 406
Query: 299 EMIEGRMHDEKVDLWSLGVLCYEFLVGKPPF 329
E++ + + VD+WSLGV+C E + G+PP+
Sbjct: 407 EVVTRKQYGPTVDIWSLGVMCIEMIEGEPPY 499
>01707
Length = 757
Score = 99.0 bits (245), Expect = 3e-21, Method: Compositional matrix adjust.
Identities = 58/201 (28%), Positives = 108/201 (53%), Gaps = 4/201 (1%)
Frame = +1
Query: 130 LEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLR 189
+E +E +G+G +G V+ R K++ ++A+K +++ + ++ RE+ + L+
Sbjct: 61 MEKYEKIGKIGEGSYGVVFKCRNKETSQLVAIKKFVESE-DDPLIKKIAMREIRMLKQLK 237
Query: 190 HPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSK-FDEQRTATYITELANALSYCH 248
HPN++RL F R++L+ +Y T+ EL + + E I + A+++CH
Sbjct: 238 HPNLVRLIEVFRRKKRLHLVFDYVD-HTLLNELDRYPRGLPEPMVKRIIYQTLLAVNFCH 414
Query: 249 SKRVIHRDIKPENLLLGSAGELKIADFGWS--VHAPSSRRTTLCGTLDYLPPEMIEGRM- 305
IHRD+KPEN+L+ G++K+ DFG++ + P T T Y PE++ G
Sbjct: 415 QYNTIHRDVKPENILITRQGQVKLCDFGFARILTGPGDEYTDYVATRWYRAPELLVGDTQ 594
Query: 306 HDEKVDLWSLGVLCYEFLVGK 326
+ VD+W++G + E L G+
Sbjct: 595 YGPPVDVWAIGCVFAELLTGQ 657
>14126
Length = 1265
Score = 98.2 bits (243), Expect = 5e-21, Method: Compositional matrix adjust.
Identities = 86/332 (25%), Positives = 146/332 (43%), Gaps = 46/332 (13%)
Frame = +3
Query: 116 SKQKNEESKKRQWALEDFEIGRPLGKGKFGNVYLARE--KQSKFILALKVLFKAQLEKAG 173
S+ + S++R + +E +G G +G VY AR+ Q +F+ ++ E G
Sbjct: 144 SESAAKMSRRRDSTEQKYEEVAVIGNGAYGTVYKARDLRNQGEFVAMKRIRLNNTEE--G 317
Query: 174 VEHQLRREVEIQSHLR---HPNILRLYGYFHDAT-----RVYLILEYA--PLGTVYRELQ 223
+ RE+ + L HPN++RL H+ R+ L+ EY L T Y
Sbjct: 318 MPMMAIREISMLKQLEQYEHPNVVRLLDVSHNTITDREIRLNLVFEYIEHDLAT-YLAKC 494
Query: 224 KLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS-VHAP 282
R + +L N + + HS R++HRD+KP+NLL+ G LK+ADFG + +++
Sbjct: 495 PSPGLGPDRIKDLMLQLLNGVDFLHSNRIVHRDLKPQNLLISKDGRLKLADFGLARIYSF 674
Query: 283 SSRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRIS 342
TT+ TL Y PE++ + VD+WS G + E + F+ ++ + K+I
Sbjct: 675 HMALTTVVVTLWYRSPEVLMQAEYGTSVDIWSCGCIFAELFTRRALFKGSSEFDQLKKIF 854
Query: 343 RV-----EFTFPDFVTEG----------------------ARDLISRLLKHNPSQRPMLR 375
V +P+ V+ A+DL+ ++L +R R
Sbjct: 855 EVIGLPPAGDWPEGVSVHRNSFRPTPPVPLQTLVPEMDPQAKDLMEKMLVFKSGRRISSR 1034
Query: 376 EVLEHPWITAN------SSKPSNCQNKESASK 401
E L HP++ + SS S +N S +
Sbjct: 1035ESLLHPYLRDDLDSIRTSSSLSTSENDSSDGR 1130
>09606
Length = 1300
Score = 97.4 bits (241), Expect = 8e-21, Method: Compositional matrix adjust.
Identities = 66/285 (23%), Positives = 126/285 (44%), Gaps = 34/285 (11%)
Frame = -3
Query: 130 LEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLR 189
+E+F + LGKG+ +Y R K + +A+ + K + ++ V + +
Sbjct: 1118 MENFVLYEELGKGEHSIIYKGRRKGTINFVAIHCIEKCK------RPEVTNTVRMTHDIS 957
Query: 190 HPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHS 249
HPN+++ + ++ + ++L++E G++ L + E + L L Y HS
Sbjct: 956 HPNVVQFHEWYETSNHLWLVVELCTGGSLADILAQDHHLPETSIRDFGIHLVTGLHYIHS 777
Query: 250 KRVIHRDIKPENLLLGSAGELKIADFG----------------------WSVHAPSS--R 285
++ D++P +LL ++G LK ADFG W++ + +
Sbjct: 776 LGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQWNIQSAEEMMK 597
Query: 286 RTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVE 345
+ G+ Y+ PE+ +G DLW+LG + YE G PPF TY T ++ E
Sbjct: 596 QVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSGHPPFLGETYDITKDKVLNKE 417
Query: 346 FTFPDFVTEGAR----------DLISRLLKHNPSQRPMLREVLEH 380
F P +G+R +L+ LL+ + ++R +++H
Sbjct: 416 FPLPK--VKGSRLSAKPSPEFLNLLESLLQKDSTRRLSWASLVKH 288
>06405
Length = 1965
Score = 97.4 bits (241), Expect = 9e-21, Method: Compositional matrix adjust.
Identities = 68/260 (26%), Positives = 118/260 (45%), Gaps = 9/260 (3%)
Frame = +1
Query: 127 QWALEDFEIGRP--LGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEI 184
+W +E EI LG G++G+VY A K+ I+A+K L E + E I
Sbjct: 241 RWEIERTEIAMKHRLGGGQYGDVYEAMWKRYNKIVAVKTL----KEDTMALNDFLEEAAI 408
Query: 185 QSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTA-TYI-TELAN 242
++HPN+++L G Y++ E+ P G + L+ ++ + TA Y+ T++A+
Sbjct: 409 MKEMKHPNLVQLLGVCTREPPFYIVTEFMPHGNLLDYLRSSTREENGPTALMYMATQIAS 588
Query: 243 ALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGT---LDYLPPE 299
++Y +K IHRD+ N L+ + +K+ADFG + T G + + PE
Sbjct: 589 GMAYLETKNFIHRDLAARNCLVADSNMVKVADFGLARLMKDDTYTAHIGAKFPIKWTAPE 768
Query: 300 MIEGRMHDEKVDLWSLGVLCYEFLV-GKPPFEANTYQETYKRISR-VEFTFPDFVTEGAR 357
+ + D+W+ GVL +E G P+ E Y + R P
Sbjct: 769 GLAFNRFSTRSDIWAFGVLLWELATYGMSPYPGVELTEVYHLLERGYRMERPPGTPADVY 948
Query: 358 DLISRLLKHNPSQRPMLREV 377
L+ + + +P RP +E+
Sbjct: 949 ILMLKCWQWDPKDRPTFKEI 1008
>09007
Length = 1440
Score = 94.4 bits (233), Expect = 8e-20, Method: Compositional matrix adjust.
Identities = 71/264 (26%), Positives = 122/264 (46%), Gaps = 20/264 (7%)
Frame = -1
Query: 135 IGRPLGKGKFGNVYLA---REKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHP 191
+ + LG+G FG V A E K +A+K L K ++ K G E +E I L H
Sbjct: 867 LSKSLGQGHFGTVRQAIWTAESGEKVQVAVKCLSKDKIHKDGQE--FLKETAIMQMLDHE 694
Query: 192 NILRLYGYFHD-ATRVYLILEYAPLGTVYRELQKLS---KFDEQRTATYITELANALSYC 247
NI+R+YG D + L+ E AP+ ++ ++++S F R + ++ + +SY
Sbjct: 693 NIVRVYGVVMDNGADIMLVTELAPMRSLLECVKEVSARVDFSVPRLCDFSQQVCDGMSYL 514
Query: 248 HSKRVIHRDIKPENLLLGSAGELKIADFGWSV-------HAPSSRRTTLCGTLDYLPPEM 300
SKR++HRD+ N+LL S ++KI+D G S + S + L + + PE
Sbjct: 513 ESKRLVHRDLAARNILLFSKSKVKISDVGVSGALGAGKEYYQSQQTIHLQNAVAWCAPES 334
Query: 301 IEGRMHDEKVDLWSLGVLCYEFLV-GKPPFEANTYQETYKRIS-----RVEFTFPDFVTE 354
D+W+ GVL +EF G P+ Q+ + + R+E PD +
Sbjct: 333 FRNLCFSSASDVWAFGVLLWEFFTHGFQPWAGLNGQQIMEAVDAPQSQRLE--QPDLCPK 160
Query: 355 GARDLISRLLKHNPSQRPMLREVL 378
++ + + P +RP ++
Sbjct: 159 EYYAVMLKCWEQEPQRRPTFSQLF 88
>13592
Length = 980
Score = 93.2 bits (230), Expect = 2e-19, Method: Compositional matrix adjust.
Identities = 68/270 (25%), Positives = 128/270 (47%), Gaps = 14/270 (5%)
Frame = +2
Query: 139 LGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYG 198
+G+G+FG VY A + ++A+K + E +++ + E++I ++H N++R YG
Sbjct: 8 IGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETRALKN-VAEELKILEGIKHKNLVRYYG 184
Query: 199 YFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIK 258
+ + +E GT+ ++ E + + +L + ++ H ++HRDIK
Sbjct: 185 IEVHREELLIFMELCSEGTLESLVELTGGLPEALSRRFTAQLLSGVAELHKHGIVHRDIK 364
Query: 259 PENL-LLGSAGELKIADFGWSVHAPSSRRTTL-------CGTLDYLPPEMI---EGRMHD 307
N+ L+ + LK+ DFG +V + TT+ GT Y+ PE+ H
Sbjct: 365 TANIFLVDGSNSLKLGDFGSAVKIQA--HTTVPGELQGYVGTQAYMAPEVFTKTNSDGHG 538
Query: 308 EKVDLWSLGVLCYEFLVGKPP---FEANTYQETYKRISRVEFTFPDFVTEGARDLISRLL 364
D+WS+G + E GK P F++N +Q +K + P+ +++ D I L
Sbjct: 539 RLADIWSVGCVVVEMASGKRPWAQFDSN-FQIMFKVGMGEKPQAPESLSQEGHDFIDHCL 715
Query: 365 KHNPSQRPMLREVLEHPWITANSSKPSNCQ 394
+H+P QR E+LE + + + N +
Sbjct: 716 QHDPKQRLSAIELLEQNFCKSGRDEECNSE 805
>13212
Length = 1067
Score = 92.4 bits (228), Expect = 3e-19, Method: Compositional matrix adjust.
Identities = 60/188 (31%), Positives = 96/188 (51%), Gaps = 10/188 (5%)
Frame = -1
Query: 206 VYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLG 265
V+ +L + L ++ +L+K E + E+ AL + H VIHRDIK N+LL
Sbjct: 1049 VFRVLWWGALDSIMVDLEK--PMTEAQICYVCHEMCMALDFLHRHHVIHRDIKAGNVLLT 876
Query: 266 SAGELKIADFGWSVHAPSS--RRTTLCGTLDYLPPEMI-----EGRMHDEKVDLWSLGVL 318
GE+K+ADFG S + +R T GT ++ PE++ + +D K D+WSLGV
Sbjct: 875 IDGEVKLADFGVSAKNTQTQQKRDTFIGTPYWMAPEVVLCETLKDTPYDFKADIWSLGVT 696
Query: 319 CYEFLVGKPPFEANTYQETYKRISRVE---FTFPDFVTEGARDLISRLLKHNPSQRPMLR 375
EF +PP + +I + + P T+ +D I++ L +P+ RP
Sbjct: 695 LIEFAQIEPPNKEMHPMRVLIKIHKSDPPTLEKPKKWTKLFKDFIAKCLVKDPNLRPTAA 516
Query: 376 EVLEHPWI 383
E+LEHP++
Sbjct: 515 ELLEHPFM 492
>01392
Length = 1806
Score = 90.5 bits (223), Expect = 1e-18, Method: Compositional matrix adjust.
Identities = 57/189 (30%), Positives = 90/189 (47%), Gaps = 34/189 (17%)
Frame = -1
Query: 230 EQRTATYITELANALSYCHSKRVIHRDIKPENLL---LGSAGELKIADF----GWSVHAP 282
E+ + + +A AL + HSK + HRD+KPEN+L L +KI DF G S
Sbjct: 1794 EREASLVVRHIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGISCDGD 1615
Query: 283 SSRRTTL---CGTLDYLPPEMIEGRM-----HDEKVDLWSLGVLCYEFLVGKPPFEANTY 334
++ L G+ +Y+ PE+++ + +D++ DLWSLG++ Y L G PPF
Sbjct: 1614 GTKTPELLTPVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILYIMLCGYPPFYGQCG 1435
Query: 335 QET---------------YKRISRVEFTFPD----FVTEGARDLISRLLKHNPSQRPMLR 375
++ + I + FP ++ A+DLI LL P +R
Sbjct: 1434 EDCGWNRGEACHDCQDMLFNSIQDGHYKFPSQEWTSISSSAKDLIRHLLVREPRKRYSAA 1255
Query: 376 EVLEHPWIT 384
+VL+HPWI
Sbjct: 1254 DVLKHPWIC 1228
>01756
Length = 1858
Score = 87.0 bits (214), Expect = 1e-17, Method: Compositional matrix adjust.
Identities = 66/222 (29%), Positives = 106/222 (47%), Gaps = 16/222 (7%)
Frame = -3
Query: 139 LGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYG 198
+G+G FG V+ AR K++K ++A+K + EK G RE++I L H N++ L
Sbjct: 1718 IGQGTFGEVFKARCKKTKQVVAMKKVLMDN-EKEGFPITALREIKILQLLNHENVVDLIE 1542
Query: 199 YFH----DATR----VYLILEYA--PLGTVYRELQKLSKFDEQRTATYITELANALSYCH 248
A R YL+ E+ L + + + E + + +L N L Y H
Sbjct: 1541 ICSTKATSANRYKSMFYLVFEFCEHDLAGLLSNMSVVFNLPEIKEV--MKQLMNGLYYIH 1368
Query: 249 SKRVIHRDIKPENLLLGSAGELKIADFG----WSVHAPS-SRRTTLCGTLDYLPPEMIEG 303
+++HRD+K N+L+ G LK+ADFG +SV+ +R T TL Y PPE++ G
Sbjct: 1367 RNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRPPELLLG 1188
Query: 304 -RMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRV 344
R + +D W G + E P + T Q I+++
Sbjct: 1187 DRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQNQLTLITQL 1062
>13066
Length = 551
Score = 87.0 bits (214), Expect = 1e-17, Method: Compositional matrix adjust.
Identities = 50/164 (30%), Positives = 87/164 (53%), Gaps = 6/164 (3%)
Frame = +3
Query: 159 LALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTV 218
LA K++ K + VE RE+++ + L HP I++++ + ++ + +A G +
Sbjct: 60 LACKIIDKEKAPVDFVEKFFPRELDLLTKLDHPYIIQIHSILQRXPKNFIFMRFAERGDL 239
Query: 219 YRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS 278
+Q++ E++ + ++ AL+Y HS V HRD+K EN+LL S +K+ADFG++
Sbjct: 240 LTYIQEVGFVKEKQAKIWFYQMTTALNYLHSYDVAHRDLKCENILLSSHFNVKLADFGFA 419
Query: 279 VHAPSS-----RRTTLCGTLDYLPPEMIEGRMHDEKV-DLWSLG 316
+ T CG+ Y PE++ G + KV D WSLG
Sbjct: 420 CACITESGEKYMSRTYCGSAAYAAPEIVYGAPYAPKVADAWSLG 551
>11780
Length = 1713
Score = 80.1 bits (196), Expect(2) = 2e-17, Method: Compositional matrix adjust.
Identities = 57/202 (28%), Positives = 100/202 (49%), Gaps = 7/202 (3%)
Frame = +3
Query: 121 EESKKRQW--ALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQL 178
+E K W A +D EIG +GKG FG+VY + V K +K E
Sbjct: 561 QEFKSGGWVIAXQDLEIGEAIGKGDFGDVYKGMYRGQP------VAIKQLKDKDRGEQSF 722
Query: 179 RREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSK--FDEQRTATY 236
+E + + LRH N++RL G T ++L+ E+ G + L+ + ++ +
Sbjct: 723 LQEASVMTSLRHDNLVRLIGVVLGET-IFLVTEFMGKGNLVEYLRSRGRSVITKKDQINF 899
Query: 237 ITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYL 296
T+ A+ Y SKR++HRD+ N+L+ G+ K++DFG + S +T++ + +
Sbjct: 900 ATDTCAAMEYLESKRLVHRDLAARNVLVHDDGKAKVSDFGLAKFGDFS-QTSVKFPIKWT 1076
Query: 297 PPEMI-EGRMHDE--KVDLWSL 315
PE + E ++H + V+LW +
Sbjct: 1077APEALRENKIH*QVRHVELWHI 1142
Score = 26.6 bits (57), Expect(2) = 2e-17, Method: Compositional matrix adjust.
Identities = 16/72 (22%), Positives = 33/72 (45%), Gaps = 2/72 (2%)
Frame = +1
Query: 309 KVDLWSLGVLCYE-FLVGKPPFEANTYQETYKRISR-VEFTFPDFVTEGARDLISRLLKH 366
K D+WS G+L +E + G+ P+ + + R P+ ++ + +
Sbjct: 1114 KSDMWSFGILLWEIYSFGRVPYPRIPLTDVVMHVERGYRMEAPEGCPPEIYSIMKQAWEL 1293
Query: 367 NPSQRPMLREVL 378
+P++RP + VL
Sbjct: 1294 DPNERPTFKSVL 1329
>04591
Length = 1117
Score = 86.3 bits (212), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 60/184 (32%), Positives = 88/184 (47%), Gaps = 12/184 (6%)
Frame = -2
Query: 171 KAGVEHQLRREVEIQSHLRHPNILRLYGYFHD--------ATRVYLILEYAP--LGTVYR 220
K G RE++I L H N+++L H + YLI EY L +
Sbjct: 1101 KEGFPITALREIKILQQLEHENVVQLQEICHTQAGPYNRYKSTFYLIFEYCDYDLAGLLN 922
Query: 221 ELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSV- 279
L+ KF +++L N L Y H+K+++HRDIK N+LL G LK+ADFG S
Sbjct: 921 NLR--VKFSLADKKNLMSQLLNGLFYIHTKQILHRDIKAANILLTRDGVLKLADFGLSRP 748
Query: 280 HAPSSRRTTLCGTLDYLPPEMIEG-RMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETY 338
S R T TL Y PPE++ G R + ++D+W +G + E KP + + Q
Sbjct: 747 WVKSKRLTNRVVTLWYRPPELLLGEREYGPEIDMWGVGCIMAEMWSRKPLMQGRSEQHQL 568
Query: 339 KRIS 342
I+
Sbjct: 567 SLIT 556
>01718
Length = 959
Score = 85.9 bits (211), Expect = 3e-17, Method: Compositional matrix adjust.
Identities = 62/209 (29%), Positives = 99/209 (47%), Gaps = 11/209 (5%)
Frame = +3
Query: 130 LEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLR 189
L+DF I +G G F V+ + + ++ALK+ H + REV++ + L+
Sbjct: 147 LDDF-ICEKIGAGFFSEVFKVTHRITGQVMALKMN-----TMTSNRHNMLREVQLLNRLQ 308
Query: 190 HPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTAT----YITELANALS 245
H NILR G +++ + EY P G + Q L K DE+ T LA L
Sbjct: 309 HANILRFMGVCVHEGQLHALTEYIPSGNLE---QLLEKKDEELPWTQRIQLTLGLARGLD 479
Query: 246 YCHSKRVIHRDIKPENLLL----GSAGELKIADFGWSVHAP---SSRRTTLCGTLDYLPP 298
Y HS R IHRD+ +N+L+ IADFG + P + G+ ++ P
Sbjct: 480 YLHSTRFIHRDLTSKNILIRREDNHGYHAVIADFGLATKIPDPLDKEKLPTVGSPYWMAP 659
Query: 299 EMIEGRMHDEKVDLWSLGVLCYEFLVGKP 327
E++ G ++E+ DL+S+G++ E P
Sbjct: 660 EVLNGHFYNERADLFSVGIIMCEITARIP 746
>17975
Length = 449
Score = 85.1 bits (209), Expect = 4e-17, Method: Compositional matrix adjust.
Identities = 51/137 (37%), Positives = 80/137 (58%), Gaps = 2/137 (1%)
Frame = +3
Query: 144 FGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDA 203
F V LAR + +A+KV+ K +L++ H L +EV ++HPN++RLY
Sbjct: 6 FAVVKLARHVFTGEKVAVKVIDKTKLDEVSRSH-LFQEVRCMKLVQHPNVVRLYEVIDTQ 182
Query: 204 TRVYLILEYAPLGTVYRELQKLSKFDEQRTAT-YITELANALSYCHSKRVIHRDIKPENL 262
T++YLILE G +Y + + S E++ A Y ++ A+SYCH V+HRD+KPEN+
Sbjct: 183 TKLYLILELGDGGDMYDYIMRHSGGLEEKLAKRYFRQIVEAISYCHKLHVVHRDLKPENV 362
Query: 263 LLGSA-GELKIADFGWS 278
+ G +K+ DFG+S
Sbjct: 363 VFFEKPGLVKLTDFGFS 413
>31885
Length = 529
Score = 84.3 bits (207), Expect = 7e-17, Method: Compositional matrix adjust.
Identities = 48/158 (30%), Positives = 81/158 (51%), Gaps = 6/158 (3%)
Frame = -2
Query: 182 VEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELA 241
V++ + L HP ++ L+ F D ++++++ G + +Q+ F E Y+ +LA
Sbjct: 519 VDMLTRLDHPFLVNLWYAFQDEEDLFMVVDLFLGGDLRYHMQQEVSFREDCVKFYLCQLA 340
Query: 242 NALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSR-RTTLCGTLDYLPPEM 300
L Y S++++HRDIKP+N+LL G + DF + T+ GT Y+ PE+
Sbjct: 339 LVLDYLRSQKIVHRDIKPDNILLDEQGHCHVTDFNIATQLEDDELATSTSGTRPYMAPEV 160
Query: 301 I-----EGRMHDEKVDLWSLGVLCYEFLVGKPPFEANT 333
E R + VD WSLGV +E L + PF ++
Sbjct: 159 YGVAINERRGYGFPVDWWSLGVSLFELLKKRRPFSVHS 46
>27546
Length = 426
Score = 82.8 bits (203), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 42/120 (35%), Positives = 70/120 (58%)
Frame = -1
Query: 159 LALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTV 218
LA K++ KA+ V+ RE+EI + L HPNI++++ ++++ + YA G +
Sbjct: 396 LACKIIDKAKAPIDFVKKFFPRELEILTRLDHPNIIQIHSILQRGPKIFIFMRYAEKGDM 217
Query: 219 YRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS 278
++K DE +T + ++A AL Y HS + HRD+K EN+LL +KIADFG++
Sbjct: 216 LSHIKKTGPIDEAQTKVWFFQMAKALQYLHSHDIAHRDLKCENILLSKRLNVKIADFGFA 37
>00486
Length = 797
Score = 82.0 bits (201), Expect = 3e-16, Method: Compositional matrix adjust.
Identities = 35/84 (41%), Positives = 53/84 (63%)
Frame = -2
Query: 288 TLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFT 347
T CGT++Y+ PE++ H + VD WSLG L Y+ L G PPF A ++T +I + +
Sbjct: 781 TFCGTIEYMAPEILTRTGHGKAVDWWSLGALMYDMLTGSPPFTAENRKKTIDKILKGKLN 602
Query: 348 FPDFVTEGARDLISRLLKHNPSQR 371
P ++T AR LI +LL+ NP++R
Sbjct: 601 LPPYLTNEARGLIKKLLRKNPAER 530
>21079
Length = 878
Score = 81.6 bits (200), Expect = 6e-16, Method: Compositional matrix adjust.
Identities = 42/148 (28%), Positives = 79/148 (53%), Gaps = 4/148 (2%)
Frame = +1
Query: 190 HPNILRLYGYFHDATRVYLILEYAPLGTVY-RELQKLSKFDEQRTATYITELANALSYCH 248
HP +L L+ F + L++E+ G ++ R ++ E+ ++ ++ + + Y H
Sbjct: 1 HPKLLMLWDAFEAPRTMVLVMEFVGAGELFERVIRDDFVLTERDCVHFVRQICSGVGYMH 180
Query: 249 SKRVIHRDIKPENLLLGS--AGELKIADFGWS-VHAPSSRRTTLCGTLDYLPPEMIEGRM 305
++ ++H D+KPEN+L S + ++KI DFG + + P L GT +++ PE++
Sbjct: 181 TQSILHLDLKPENVLCVSDNSNQIKIIDFGLARFYKPGDSLQVLFGTPEFIAPEVVNYDE 360
Query: 306 HDEKVDLWSLGVLCYEFLVGKPPFEANT 333
+ D+WS+GV+CY L G P T
Sbjct: 361 INFTTDMWSIGVICYILLSGLSPSRVTT 444
>00392
Length = 668
Score = 80.5 bits (197), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 48/175 (27%), Positives = 91/175 (52%), Gaps = 9/175 (5%)
Frame = +3
Query: 177 QLRREVEIQSHLRHPNILRLYGYFHDATR-----VYLILEYAPLGTVYRELQKLSKFDEQ 231
+ + E E+ L+HPNI+R + Y+ + + L+ E GT+ L++ K + +
Sbjct: 69 RFKEEAEMLKELQHPNIVRFFDYWEEHNHRNRKVIILVTELMTSGTLKTYLKRFKKPNVK 248
Query: 232 RTATYITELANALSYCHSKR--VIHRDIKPENLLL-GSAGELKIADFGWSVHAPSSRRTT 288
+ ++ L + H++ VIHRD+K +N+ + G G +KI D G + S +
Sbjct: 249 ILKNWCRQVLKGLYFLHTRTPPVIHRDLKCDNIFITGPTGSVKIGDLGLATLKNQSFAKS 428
Query: 289 LCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPF-EANTYQETYKRIS 342
+ GT +++ PEM E +DE VD+++ G+ E + P+ E + + YKR++
Sbjct: 429 VIGTPEFMAPEMYEEH-YDEAVDVYAFGMCMLEMASSEYPYSECSNAAQIYKRVT 590
>01966
Length = 1735
Score = 79.0 bits (193), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 42/135 (31%), Positives = 70/135 (51%), Gaps = 4/135 (2%)
Frame = -1
Query: 173 GVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEY--APLGTVYRELQKLSKFDE 230
GV RE+ + LRH NI+ L + R++L+ E+ L + + D
Sbjct: 1588 GVPSSAIREIAMLRELRHTNIVCLEDVIMEDERLFLVFEFLSMDLKMYIDKFPEGVVLDR 1409
Query: 231 QRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGW--SVHAPSSRRTT 288
+ +Y+ ++ +++CH +R++HRD+KP+NLL+ G +KIADFG + P T
Sbjct: 1408 RLVKSYVFQIVTGINFCHQRRIVHRDLKPQNLLINHTGAIKIADFGMARTFALPVRAYTH 1229
Query: 289 LCGTLDYLPPEMIEG 303
TL Y PE++ G
Sbjct: 1228 EVVTLWYRAPEILMG 1184
>19761
Length = 473
Score = 76.3 bits (186), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 40/142 (28%), Positives = 77/142 (54%), Gaps = 4/142 (2%)
Frame = -3
Query: 230 EQRTATYITELANALSYCHSKR--VIHRDIKPENLLLGSAGELKIADFGWS--VHAPSSR 285
E+ ++ + A+AL+Y H+ ++HRD+KP+N+ + G++++ D G + + P+
Sbjct: 426 ERLIVCWLMQTASALNYMHTHTPVILHRDLKPQNIYVTEKGDVRLGDLGLARKLTGPADF 247
Query: 286 RTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVE 345
T+ GT+ YL PE++ + ++ K D+WSLG + Y+ K E + + +
Sbjct: 246 ATSQVGTIMYLSPEILSQQPYNSKSDIWSLGCVFYDITGKKGSDEMGVMFLLVQVMGGRK 67
Query: 346 FTFPDFVTEGARDLISRLLKHN 367
PD ++ RD ISR+L +
Sbjct: 66 LPLPDHYSQEFRDTISRMLTKD 1
>19094
Length = 898
Score = 70.1 bits (170), Expect(2) = 6e-14, Method: Compositional matrix adjust.
Identities = 39/103 (37%), Positives = 57/103 (55%), Gaps = 2/103 (1%)
Frame = +1
Query: 230 EQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS--VHAPSSRRT 287
E+ AT + L Y HS+R IHRDIK N+LL + G K+ADFG + + ++R
Sbjct: 55 EREIATILYYTLKGL*YLHSRRKIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRN 234
Query: 288 TLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFE 330
T+ GT ++ PE+I+ +D D+WSLG+ E G E
Sbjct: 235 TVIGTPYWMAPEVIQEIGYDCVADIWSLGITALEMAEGNLHME 363
Score = 24.6 bits (52), Expect(2) = 6e-14, Method: Compositional matrix adjust.
Identities = 12/38 (31%), Positives = 19/38 (50%)
Frame = +3
Query: 346 FTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWI 383
F PD + D +S+ L NP R ++L+H +I
Sbjct: 417 FRQPDKWSTEFIDFVSKCLVKNPENRATAVDLLQHDFI 530
>26560
Length = 398
Score = 74.7 bits (182), Expect = 7e-14, Method: Composition-based stats.
Identities = 40/131 (30%), Positives = 67/131 (51%), Gaps = 1/131 (0%)
Frame = -1
Query: 218 VYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGW 277
++ L + F E+ Y E+ L + HS+ V++RD+KP N+LL G ++I+D G
Sbjct: 395 LHYHLSQHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGL 216
Query: 278 SVHAPSSRRTTLCGTLDYLPPE-MIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQE 336
+ R GT Y+ PE +++G+ +D D +S G + Y+ L G PF + +
Sbjct: 215 ACDFSKKRPHASVGTHGYMAPEVLMKGQSYDSSADWFSFGCMLYKLLKGHSPFR--QHNQ 42
Query: 337 TYKRISRVEFT 347
RI R+ T
Sbjct: 41 GQARIDRMTMT 9
>29581
Length = 1278
Score = 72.0 bits (175), Expect = 4e-13, Method: Compositional matrix adjust.
Identities = 63/235 (26%), Positives = 101/235 (42%), Gaps = 38/235 (16%)
Frame = -2
Query: 187 HLRHPNILRL----YGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELAN 242
+LRH NI++L G D+ ++L++EY + F E + + +L
Sbjct: 1187 NLRHQNIVQLQEVVVGKSLDS--LFLVMEYCEQDLASLLDNMPAPFSESQVKCIVLQLLK 1014
Query: 243 ALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVH--APSSRRTTLCGTLDYLPPEM 300
L Y H +IHRD+K NLL+ G +KIADFG + + P T TL Y PE+
Sbjct: 1013 GLRYLHEAFIIHRDLKVSNLLMTDKGCVKIADFGLARNYGKPQKPMTPKVVTLWYRAPEL 834
Query: 301 IEG-RMHDEKVDLWSLGVLCYEFLVGKPPFEANT-------------------------- 333
+ G + H +D+WS G + E L KP +
Sbjct: 833 LFGSKTHSTAIDMWSAGCILGELLGHKPLMPGRSDLQQIELIMELLGTPNDTIWPGFSQL 654
Query: 334 ---YQETYKR--ISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWI 383
Q T K+ + + TFP +++E L++ L ++P +R + LEH +
Sbjct: 653 PAFEQFTLKKQPYNNLRHTFP-WLSESGIRLLNGLFMYHPQKRATAEDCLEHSYF 492
>20152
Length = 445
Score = 68.9 bits (167), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 32/96 (33%), Positives = 50/96 (52%), Gaps = 1/96 (1%)
Frame = +1
Query: 298 PEMIEGRMHDE-KVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGA 356
PE++ G +D VD+WSLGV+ Y +VG+ PF+ ET I + P ++
Sbjct: 1 PEILLGDSYDAPAVDVWSLGVILYMLVVGEAPFQEANDSETLTMIMDCRYQIPPHISHKC 180
Query: 357 RDLISRLLKHNPSQRPMLREVLEHPWITANSSKPSN 392
+DLI ++L+ P R L +L HPW+ P+
Sbjct: 181 QDLIEKMLQREPVDRASLPHILAHPWLNDGDLTPTT 288
>27405
Length = 532
Score = 67.8 bits (164), Expect = 7e-12, Method: Compositional matrix adjust.
Identities = 47/175 (26%), Positives = 84/175 (48%), Gaps = 5/175 (2%)
Frame = -3
Query: 144 FGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLR----HPNILRLYGY 199
FG VY R+ + + A+K L K +++ G E E + S + P I+ +
Sbjct: 527 FGEVYGCRKADTGKMYAMKCLDKKRIKMKGGETLALNERIMLSLVSTGEGSPFIVCMTYA 348
Query: 200 FHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKP 259
F ++ IL+ G ++ L + F E+ Y E+ L + HS+ V++RD+KP
Sbjct: 347 FQTPEKLCFILDLMNGGDLHYHLSQHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKP 168
Query: 260 ENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPE-MIEGRMHDEKVDLW 313
N+LL G ++I+D G + + GT Y+ PE +++G+ +D D +
Sbjct: 167 ANILLDENGHVRISDLGLACDFSKKKPHASVGTHGYMAPEVLMKGQAYDSSADWF 3
>26711
Length = 405
Score = 65.9 bits (159), Expect = 3e-11, Method: Composition-based stats.
Identities = 39/132 (29%), Positives = 72/132 (54%), Gaps = 8/132 (6%)
Frame = -2
Query: 237 ITELANALSYCHSKRVIHRDIKPENLLLG--SAGELKIADFGWSVHAPSSRRTTLC-GTL 293
+ ++ + L + H++ V+H D+KP NLLL +++ DFG + + T L GT
Sbjct: 398 VKQVLDILQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARKLYPPQETFLNHGTP 219
Query: 294 DYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTF---PD 350
+ PE ++ + D+W +GVL Y L G+ PF+A++ E+ K+ +++F P
Sbjct: 218 GFTSPEALDVKPISTASDVWGVGVLAYILLSGQSPFQADSATESLKKTQTCDWSFDVCPS 39
Query: 351 F--VTEGARDLI 360
F +++ A+D I
Sbjct: 38 FSNMSQDAKDFI 3
>19301
Length = 712
Score = 65.1 bits (157), Expect = 5e-11, Method: Compositional matrix adjust.
Identities = 33/101 (32%), Positives = 56/101 (55%), Gaps = 2/101 (1%)
Frame = +2
Query: 180 REVEIQS--HLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYI 237
+E +I++ L HPNI+ G A +I+EY P G +Y L+ + +
Sbjct: 410 KETDIRNLRKLNHPNIISFKGVCTQAPCYCIIMEYCPYGQLYEVLRDGKEIPPALVLDWS 589
Query: 238 TELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS 278
++A+ ++Y HS ++IHRD+K N+L+ +KI+DFG S
Sbjct: 590 KQIASGMNYLHSHKIIHRDLKSPNVLVAKNDVVKISDFGTS 712
>38560
Length = 479
Score = 64.7 bits (156), Expect = 6e-11, Method: Compositional matrix adjust.
Identities = 33/111 (29%), Positives = 58/111 (52%), Gaps = 1/111 (0%)
Frame = -3
Query: 287 TTLCGTLDYLPPEMIEGRMH-DEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVE 345
TT CG+ Y PE+I G + + D+WS+GVL Y L G PF+ ++ + +
Sbjct: 411 TTCCGSPAYAAPELISGLEYLGSEADIWSMGVLLYALLCGYLPFDDEKXSHL*QKNQKRK 232
Query: 346 FTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQNK 396
P++++E L+ +L+ +PS R +R +L+H W+ + P +K
Sbjct: 231 DEVPEWLSEDTTKLLEGMLQTDPSHRITIRRLLDHHWLNQGFNVPVEWASK 79
>14477
Length = 493
Score = 63.9 bits (154), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 44/142 (30%), Positives = 73/142 (51%), Gaps = 2/142 (1%)
Frame = -1
Query: 139 LGKGKFGNVY--LAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRL 196
LG G FG+V + R + +A+KVL A L+ + V+ +L +E E+ + H +I+RL
Sbjct: 466 LGAGNFGSVMKGVCRLDDREIPVAIKVLKNADLDPS-VQSELIKEAEVMKKMDHMHIVRL 290
Query: 197 YGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRD 256
G T + L+LE A LG + + L K + +++ + Y + + +HRD
Sbjct: 289 IGLCEGET-MMLVLELAKLGPLNKFLPKNKHLPLWNILELMWQVSQGMEYLEANKFVHRD 113
Query: 257 IKPENLLLGSAGELKIADFGWS 278
+ N+LL KI+DFG S
Sbjct: 112 LAARNILLCDEHFAKISDFGMS 47
>04852
Length = 1462
Score = 63.9 bits (154), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 40/151 (26%), Positives = 75/151 (49%), Gaps = 5/151 (3%)
Frame = +1
Query: 235 TYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTL- 293
+Y ++A + + S++ IHRD+ N+L+ LKIADFG S ++ + G L
Sbjct: 337 SYAFQIARGMEFLASRKCIHRDLAARNVLVTEEHVLKIADFGLSRTGDYYKKRS-GGRLP 513
Query: 294 -DYLPPEMIEGRMHDEKVDLWSLGVLCYE-FLVGKPPFEANTYQETYKRISRVEFTF--P 349
++ PE + + K D+WS GV+ +E F +G P+ + +E Y ++ + P
Sbjct: 514 VKWMAPEALFDMRYTTKSDVWSFGVVLWEIFSLGGMPYASIPNEELYSKLLDDAYRMPRP 693
Query: 350 DFVTEGARDLISRLLKHNPSQRPMLREVLEH 380
+ + ++ R + PS RP +++ H
Sbjct: 694 ELASGNLYAIMERCWLNRPSDRPEFSQLVGH 786
>06358
Length = 1517
Score = 63.5 bits (153), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 65/273 (23%), Positives = 121/273 (44%), Gaps = 40/273 (14%)
Frame = +3
Query: 140 GKGKFGNVYLAREKQSK-----FILALKVLFK-AQLEKAGVEHQLRREVEIQSHLRHPNI 193
G G V+ A +K +K F+ K + + ++ ++ + LR V+ + LRHP I
Sbjct: 33 GPGLLWKVFAASKKSTKEEASVFVFEKKSVDRYSRRDREAIVEVLRVGVQQLTKLRHPKI 212
Query: 194 LRLYGYFHD-------------ATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITEL 240
L + + A+ ++ + + + TV +ELQ +D + + ++
Sbjct: 213 LAVINPLEESRETLAFATEPVFASLANVLGDLSSIXTVPKELQDYQLYDVE-IKHGLLQV 389
Query: 241 ANALSYCHSK-RVIHRDIKPENLLLGSAGELKIADFGWSVHA--PSSR---------RTT 288
AL + H+ +++HR++ PE ++L G K+A + + V + P S R+
Sbjct: 390 TEALGFLHNDAKMMHRNVCPEAIMLTKLGSWKLAGYEFCVRSSDPQSTDPSYPFYEWRSD 569
Query: 289 LCGT----LDYLPPEMIEGRMHDEKVDLWSLGVLCYE-FLVGKPPFEAN----TYQETYK 339
+ LD++ PE + D++SLG+L Y F GKP FE N ++ +
Sbjct: 570 IAPVTQPHLDFMAPEYVLTMQCGTGSDMFSLGLLVYSVFAKGKPLFECNGELSAFKSNAE 749
Query: 340 RISRVEFTFPDFVTEGARDLISRLLKHNPSQRP 372
+ + + V E RD + LL P+ RP
Sbjct: 750 ELRHMRVSLLGVVPEDLRDHVKLLLNIEPAVRP 848
>04138
Length = 800
Score = 63.5 bits (153), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 51/177 (28%), Positives = 72/177 (40%), Gaps = 40/177 (22%)
Frame = +1
Query: 244 LSYCHSKRVIHRDIKPENLLLGSAGELKIADFG----WSVHAPS-SRRTTLCGTLDYLPP 298
L Y H +++HRD+K N+L+ G LK+ADFG +SV+ +R T TL Y PP
Sbjct: 52 LYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRPP 231
Query: 299 EMIEG-RMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGAR 357
E++ G R + +D W G + E P + T Q I+++ + V G
Sbjct: 232 ELLLGDRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQNQLTLITQLCGSITPEVWPGVT 411
Query: 358 ----------------------------------DLISRLLKHNPSQRPMLREVLEH 380
DL RLLK +PSQR E L H
Sbjct: 412 QLSMYHQIKGALAAGRKNIIRDRFARILKDPYGLDLFERLLKMDPSQRISADEALNH 582
>21808
Length = 1011
Score = 63.2 bits (152), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 43/166 (25%), Positives = 73/166 (43%), Gaps = 5/166 (3%)
Frame = +1
Query: 181 EVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYI-TE 239
E +I LRHP +++LY +++I E G++ LQ + + I +
Sbjct: 82 EAQIMKKLRHPKLIQLYAVCTQDDPIFIITELMKNGSLLEFLQGKGRVLKLPALIDIGAQ 261
Query: 240 LANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGT---LDYL 296
+A ++Y S+ IHRD+ N+L+ +KIADFG + G + +
Sbjct: 262 IACGMAYLESQNYIHRDLAARNILVSDNNTVKIADFGLARVIKEDEYEARVGARFPIKWT 441
Query: 297 PPEMIEGRMHDEKVDLWSLGVLCYEFLV-GKPPFEANTYQETYKRI 341
PE K D+WS G+L E + G+ P+ T E ++
Sbjct: 442 APEAANYNRFTIKSDVWSFGILLTETVTYGRVPYPGMTNAEVLHQV 579
>00715
Length = 1788
Score = 61.6 bits (148), Expect = 5e-10, Method: Compositional matrix adjust.
Identities = 47/177 (26%), Positives = 76/177 (42%), Gaps = 33/177 (18%)
Frame = +1
Query: 188 LRHPNILRLYGY-----FHDATRVYLILEYAP---LGTVYRELQKLSKFDEQRTATYITE 239
LRH N++ + G F D +L +EY L T+ + Q+ D + +
Sbjct: 97 LRHVNVVSILGATSLHRFEDGA--WLAMEYVGPLNLQTILNDHQQ--DIDSSMRLSLALQ 264
Query: 240 LANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVH------------------- 280
+A L Y HS ++H D+KP N LL +L+IADFG H
Sbjct: 265 MARGLHYLHSINIVHLDLKPANCLLTRDLKLRIADFG-CCHQLTPTGLDMGEREGGMAGN 441
Query: 281 ------APSSRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEA 331
+ + L GTL Y PE+++G + D++SLG+ ++ + P+E
Sbjct: 442 ELELTPVQGAWKNELAGTLAYRAPELLKGLQPSVRSDVYSLGITLWQMCTRQGPYEG 612
>14116
Length = 1017
Score = 61.2 bits (147), Expect = 6e-10, Method: Compositional matrix adjust.
Identities = 56/217 (25%), Positives = 96/217 (44%), Gaps = 24/217 (11%)
Frame = -1
Query: 131 EDFEIGRPLGKGKFGNV---YLAR-EKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQS 186
E +G +GKG FG V +L E++ ++A+K L RE+E+QS
Sbjct: 636 EFLTMGEEIGKGNFGCVKRGFLTLPEQKGDILVAVKTLHNNN----------PREIELQS 487
Query: 187 HLR---------HPNILRLYGY---FHDATRVYL-ILEYAPLGTVYRELQKLSKFDEQRT 233
L+ H N+L L G D V L +++ L T R+ Q +
Sbjct: 486 FLQEALIMKDFHHSNVLTLIGICLNLDDMPLVVLPFMKHGDLLTYIRDDQHQPTIKD--L 313
Query: 234 ATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS-------VHAPSSRR 286
Y ++A + Y + +HRD+ N +L +K+ADFG + ++ +++
Sbjct: 312 IMYGVDIARGMDYLAGLKFVHRDLAARNCMLDEDFHVKVADFGLARDIYEKEYYSSENKK 133
Query: 287 TTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFL 323
L + ++ E +E +D K D+WS GV+ +E L
Sbjct: 132 AKL--PVKWMALESLEKGNYDSKTDVWSYGVVLWELL 28
>28157
Length = 400
Score = 61.2 bits (147), Expect = 8e-10, Method: Compositional matrix adjust.
Identities = 39/104 (37%), Positives = 57/104 (54%), Gaps = 7/104 (6%)
Frame = +3
Query: 180 REVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLS---KFDEQRTATY 236
+E++ S + HPNI+ LYG D V L++EYA G++Y L ++ +
Sbjct: 57 QELKQLSRVSHPNIVCLYGACRDHP-VCLVMEYAEGGSLYNVLHGSGPQPQYTAAHAMNW 233
Query: 237 ITELANALSYCHS---KRVIHRDIKPENLLLGSAG-ELKIADFG 276
+ + A + Y H K +IHRD+KP NLLL G +LKI DFG
Sbjct: 234 LLQCALGVEYLHGMKPKALIHRDLKPPNLLLIQCGTKLKICDFG 365
>12672
Length = 773
Score = 60.8 bits (146), Expect = 9e-10, Method: Compositional matrix adjust.
Identities = 45/161 (27%), Positives = 69/161 (42%), Gaps = 24/161 (14%)
Frame = +3
Query: 241 ANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTT------LCGTLD 294
A+ + Y + +HRDIK N+LL S K+ DF V APS T + GT
Sbjct: 21 ASGIQYLNDNGHVHRDIKTANILLDSEYTAKVGDFATVVSAPSGEGKTVQNASVVIGTAA 200
Query: 295 YLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTY------------------QE 336
YL PE I + K+D +S GV+ E + G A Y +E
Sbjct: 201 YLAPEAIHFDVS-TKLDSYSFGVVLLEVITG---LVAQDYSREERTLSSHIMENVEEPEE 368
Query: 337 TYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREV 377
+ + + T+PD + D+ R L + QRP ++++
Sbjct: 369 IHDFVDQSAGTWPDGAVDKLYDISMRCLNLSKKQRPNVKDI 491
>07940
Length = 1336
Score = 60.8 bits (146), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 36/100 (36%), Positives = 54/100 (54%), Gaps = 5/100 (5%)
Frame = -3
Query: 235 TYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS--VHAPSSRRTTLCGT 292
+Y ++A + Y SK+ IHRD+ N+L+ LKIADFG + + R T G
Sbjct: 335 SYAYQVARGMEYLASKQCIHRDLAARNVLVAEEYVLKIADFGLTRNLQQFDYYRKTTDGR 156
Query: 293 L--DYLPPEMIEGRMHDEKVDLWSLGVLCYE-FLVGKPPF 329
L ++ PE + R + K D+WS GVL +E F +G P+
Sbjct: 155 LPVKWMAPEALFDRKYTSKSDVWSYGVLLWEIFTLGGNPY 36
Score = 34.3 bits (77), Expect = 0.088, Method: Compositional matrix adjust.
Identities = 28/95 (29%), Positives = 49/95 (51%), Gaps = 7/95 (7%)
Frame = -3
Query: 131 EDFEIGRPLGKGKFGNVYLAREKQSKF------ILALKVLFKAQLEKAGVEHQLRREVEI 184
E +G LG+G FG V + E F +A+K+L + ++ ++ L RE+E+
Sbjct: 842 ERLVLGDRLGEGAFGLV-MKGEAMGIFKDNNSVTVAVKMLKEDATDREMMD--LIREMEM 672
Query: 185 QSHL-RHPNILRLYGYFHDATRVYLILEYAPLGTV 218
+ +H NI+ L G +Y+I+E+AP G +
Sbjct: 671 MKVIGKHKNIINLLGCCTQRGALYVIVEFAPHGNL 567
>03508
Length = 1463
Score = 60.8 bits (146), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 31/109 (28%), Positives = 57/109 (52%), Gaps = 3/109 (2%)
Frame = +1
Query: 223 QKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAG-ELKIADFGWS-VH 280
Q F + Y+ EL AL +CHS ++HRD+KP N+++ +L++ D+G + +
Sbjct: 847 QLYQTFTDYDIRFYLYELMKALDFCHSMGIMHRDVKPHNVMIDHENKKLRLIDWGLAEFY 1026
Query: 281 APSSRRTTLCGTLDYLPPE-MIEGRMHDEKVDLWSLGVLCYEFLVGKPP 328
P + + PE +++ +M+D +D+WSLG + + K P
Sbjct: 1027HPGMEYNVRVASRYFKGPELLLDYQMYDYSLDMWSLGCMFASMIFRKEP 1173
>26009
Length = 886
Score = 40.8 bits (94), Expect(2) = 3e-09, Method: Compositional matrix adjust.
Identities = 17/49 (34%), Positives = 30/49 (61%)
Frame = +3
Query: 216 GTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLL 264
GT ++ + + + +L +AL + HSK+++HRDIKPEN+L+
Sbjct: 666 GTCLTPSRRNKACGSREAKSVMKQLVSALDFMHSKQLVHRDIKPENVLI 812
Score = 38.1 bits (87), Expect(2) = 3e-09, Method: Compositional matrix adjust.
Identities = 26/91 (28%), Positives = 47/91 (51%), Gaps = 2/91 (2%)
Frame = +2
Query: 131 EDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLR- 189
E +++ + LG+G +G V LAR + + +ALK+L K+ + + +RE ++ L
Sbjct: 416 EHYDVCKELGRGTYGKVVLARCRHTGTQVALKLLPKSCTKL----REFQREFQLSYFLSP 583
Query: 190 HPNILRLYGY-FHDATRVYLILEYAPLGTVY 219
H NI+ Y F + E+A LG ++
Sbjct: 584 HANIIDTYNVAFQTRSSYVFAQEHAVLGDLF 676
>12786
Length = 460
Score = 58.9 bits (141), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 37/127 (29%), Positives = 54/127 (42%), Gaps = 24/127 (18%)
Frame = -3
Query: 228 FDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRT 287
D Y E+ A+ H++ VIH D+KP N +L AG LK+ DFG + + +
Sbjct: 419 LDRMMIKFYWREMLRAVKALHNEGVIHSDLKPANFML-VAGNLKLIDFGIANTLQQDKTS 243
Query: 288 TL----CGTLDYLPPEMIEGRMHDE--------------------KVDLWSLGVLCYEFL 323
L GT Y+ PE I D + D+WSLG + Y +
Sbjct: 242 VLKDSRVGTPSYMSPEAIMAACDDSADDSMEEDGHRTKPKYKVGVRSDVWSLGCILYNMV 63
Query: 324 VGKPPFE 330
G+ PF+
Sbjct: 62 YGRTPFQ 42
>18663
Length = 600
Score = 57.8 bits (138), Expect = 7e-09, Method: Compositional matrix adjust.
Identities = 32/112 (28%), Positives = 52/112 (46%), Gaps = 15/112 (13%)
Frame = +2
Query: 287 TTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEA---------NTYQET 337
+T CGT +Y+ PE++ G + VD W+LGVL YE L G+ PF+ NT
Sbjct: 2 STFCGTPNYIAPEILRGEDYGFSVDWWALGVLLYEMLAGRSPFDIAGASENPDQNTEDYL 181
Query: 338 YKRISRVEFTFPDFVTEGARDLISRLLKHNPSQR------PMLREVLEHPWI 383
++ I P ++ A ++ L NP+ R +++ HP+
Sbjct: 182 FQVILEKTIRIPRSLSVKAASVLKGFLNKNPADRLGCHRESAFMDIVNHPFF 337
>28638
Length = 1458
Score = 55.8 bits (133), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 41/132 (31%), Positives = 60/132 (45%), Gaps = 5/132 (3%)
Frame = -1
Query: 203 ATRVYLILEYAP-LGTVYRELQKLSKFDEQRTATYITELANALSYCHS--KRVIHRDIKP 259
AT L +P + T Q L T + +L AL + + +IH D+KP
Sbjct: 924 ATTCVWCLSCSPTISTTCYATQTLEGVSLNLTRKFAQQLCTALLFLATPEMNIIHCDLKP 745
Query: 260 ENLLLGSA--GELKIADFGWSVHAPSSRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGV 317
EN+LL + +KI DFG S R + Y PE++ G +D +D+WSLG
Sbjct: 744 ENILLCNPKRSAIKIVDFGSSCQL-GQRIYQYIQSRFYRSPEVLLGVPYDLAIDMWSLGC 568
Query: 318 LCYEFLVGKPPF 329
+ E G+PP
Sbjct: 567 ILVEMHTGEPPL 532
>02638
Length = 1490
Score = 53.1 bits (126), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 27/104 (25%), Positives = 52/104 (50%), Gaps = 5/104 (4%)
Frame = +1
Query: 289 LCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFT- 347
L GT+ ++ PE++ G + D+WS+G + E +PP+ ++ I ++ +
Sbjct: 16 LLGTIAFMAPEVLRGESYGRACDVWSVGCVMIEMCTCRPPWNSHDISNHLALIFKIASSV 195
Query: 348 ----FPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANS 387
P+ ++ RDL+ R L+ + RP +++L HP T S
Sbjct: 196 DPPPIPENMSPPVRDLMLRCLEQDSDFRPSAKDLLMHPLFTKYS 327
>11185
Length = 473
Score = 52.4 bits (124), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 30/110 (27%), Positives = 48/110 (43%), Gaps = 24/110 (21%)
Frame = +1
Query: 240 LANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFG----------------------W 277
L L Y HS ++ D++P +LL ++G LK ADFG W
Sbjct: 28 LVTGLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQW 207
Query: 278 SVHAPSS--RRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVG 325
++ + ++ G+ Y+ PE+ +G DLW+LG + YE G
Sbjct: 208 NIQSAEEMMKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSG 357
>25019
Length = 730
Score = 52.4 bits (124), Expect = 4e-07, Method: Compositional matrix adjust.
Identities = 25/59 (42%), Positives = 35/59 (59%), Gaps = 2/59 (3%)
Frame = +3
Query: 260 ENLLLGSAGELKIADFGWSVHAPSSRRTT--LCGTLDYLPPEMIEGRMHDEKVDLWSLG 316
EN+LL G +K+ DFG A + R T CGT++Y+ PE++ H + VD WSLG
Sbjct: 261 ENVLLDKDGHVKLTDFGLCKEAITGTRVTHTFCGTIEYMAPEILTRTGHGKAVDWWSLG 437
>29590
Length = 320
Score = 38.9 bits (89), Expect(2) = 1e-06, Method: Composition-based stats.
Identities = 17/41 (41%), Positives = 24/41 (58%)
Frame = +3
Query: 289 LCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPF 329
+ GT DY+ PE+++ + D+WSLGVL Y L PF
Sbjct: 54 IIGTPDYVAPEVLDYEPLSIQTDMWSLGVLSYVMLTACSPF 176
Score = 31.2 bits (69), Expect(2) = 1e-06, Method: Composition-based stats.
Identities = 16/41 (39%), Positives = 24/41 (58%), Gaps = 4/41 (9%)
Frame = +2
Query: 335 QETYKRISRVEFTFPD----FVTEGARDLISRLLKHNPSQR 371
QET+ IS+V+ FPD ++ A+D I +LL +P R
Sbjct: 191 QETFCNISQVKLDFPDDLFSHISPHAKDFIKKLLVKDPRHR 313
>27274
Length = 396
Score = 49.7 bits (117), Expect = 2e-06, Method: Composition-based stats.
Identities = 30/97 (30%), Positives = 45/97 (46%), Gaps = 12/97 (12%)
Frame = -1
Query: 299 EMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEAN------------TYQETYKRISRVEF 346
E++ G+ H VD+WSLG+L +E L G PFE Y + + SR
Sbjct: 375 ELLRGQQHGPTVDMWSLGILLHELLSGHVPFEPERGSRQMARNMMAVYAQIIRGSSRDVC 196
Query: 347 TFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWI 383
T GA D + RL++ ++R ++ HPWI
Sbjct: 195 DGLALSTHGA-DFLRRLVQLEDTKRLTSQQAFSHPWI 88
>31120
Length = 439
Score = 48.9 bits (115), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 33/99 (33%), Positives = 53/99 (53%), Gaps = 6/99 (6%)
Frame = +1
Query: 299 EMIEGRMHDEKV-DLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTF----PDFVT 353
E++ G +D K+ D WSLGV+ + L GK PF+ + + + +++F D V+
Sbjct: 1 EVVCGVPYDPKMADAWSLGVILFIMLNGKMPFDDSNLNKLLEDQRSKKYSFRRKLQDLVS 180
Query: 354 EGARDLISRLLKHNPSQRPMLREVLEHPWI-TANSSKPS 391
AR +S LL+ N + R L EVL W+ T + +PS
Sbjct: 181 PNARSTVSVLLEPNSAMRWDLNEVLNCQWLQTIDEPRPS 297
>37602
Length = 804
Score = 48.5 bits (114), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 32/99 (32%), Positives = 46/99 (46%), Gaps = 3/99 (3%)
Frame = -1
Query: 189 RHPNILRLYGYFHDATR---VYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALS 245
R NI GYF R +++ +EY G++ E + A E L
Sbjct: 354 RIVNIQTFVGYFDSYLRREKLWIAMEYCGGGSMQDIYHVTGPLTEPQIAFVCRETLKGLH 175
Query: 246 YCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSS 284
Y H + +HRDIK N+LL G++K+ADF W V + S
Sbjct: 174 YLHRRGKMHRDIKGANILLTEEGDVKLADF-WRVSSNHS 61
>07833
Length = 1504
Score = 48.1 bits (113), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 45/213 (21%), Positives = 88/213 (41%), Gaps = 21/213 (9%)
Frame = -3
Query: 188 LRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKF--DEQRTATYITELANALS 245
HPN+L + + + LI ++ P G++Y L S D+ ++ + ++A +
Sbjct: 1448 FNHPNVLPVLACCNQPPNLVLISQFMPFGSLYNTLHGESGIVVDQNQSLRFAMDIARGME 1269
Query: 246 YCHSKRVIHRDIKPE--NLLLGS---------AGELKIADFGWSVHAPSSRRTTLCGTLD 294
+ HS ++P N LL S + +AD+ +S H +
Sbjct: 1268 FLHS-------MEPTIPNFLLTSKHVMIDEDLTARINMADYCFSFHEKGKVYSP-----A 1125
Query: 295 YLPPEMIEGRMHD---EKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISR--VEFTFP 349
++ PE ++ R D D+WS +L +E + PF + E +++ + + P
Sbjct: 1124 WMAPEALQRRPDDINTRAADMWSFAILMWELETREVPFAELSSMEVGMKVALEGLRISIP 945
Query: 350 DFVTEGARDLISRLLKHNPSQRP---MLREVLE 379
++ LI + P +RP M+ +LE
Sbjct: 944 PGISLHMSRLIKICMNEEPGKRPRFDMIIPILE 846
>32000
Length = 644
Score = 48.1 bits (113), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 39/148 (26%), Positives = 63/148 (42%), Gaps = 31/148 (20%)
Frame = -1
Query: 267 AGELKIADFGWS--VHAPSSRRTTLCGTLDYLPPEMIEG-RMHDEKVDLWSLGVLCYEFL 323
++KIADFG + P T TL Y PE++ G R + VD+WSLG + E +
Sbjct: 581 TAKMKIADFGLARVFGLPVRTYTHEVITLWYRAPEILLGCRFYSVPVDIWSLGCIFVEMM 402
Query: 324 VGKPPFEANTYQETYKRISRVEFT-----------FPDF-----------------VTEG 355
+ F ++ + RI R T PD+ +++
Sbjct: 401 TRRALFPGDSEIDQLYRIFRTLGTPDEKVWPGVSKLPDYKPTFPKWPLKNLETVVSLSKV 222
Query: 356 ARDLISRLLKHNPSQRPMLREVLEHPWI 383
DL+ R+L +NP++R R + HP+
Sbjct: 221 GLDLLKRMLTYNPNRRISARSAMRHPYF 138
>07291
Length = 833
Score = 47.8 bits (112), Expect = 8e-06, Method: Compositional matrix adjust.
Identities = 25/97 (25%), Positives = 50/97 (51%), Gaps = 6/97 (6%)
Frame = +1
Query: 239 ELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHA-PSSRRTT----LCGTL 293
++A+ ++Y +V+HR++ N ++ G L+++D+G + P S T +
Sbjct: 73 QIADGMAYLQEVKVVHRNLAARNCIVTEDGRLQLSDYGVTGSLFPQSYYTADDSPARDLV 252
Query: 294 DYLPPEMIEGRMHDEKVDLWSLGVLCYEFLV-GKPPF 329
++ PE I+ K D+W+ GV+ +E L G P+
Sbjct: 253 KWMAPETIDNFHFSSKSDVWAFGVVLWELLTRGITPY 363
>01106
Length = 878
Score = 46.6 bits (109), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 46/147 (31%), Positives = 70/147 (47%), Gaps = 15/147 (10%)
Frame = +3
Query: 133 FEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQ--LEKAGVEHQLRREVEIQSHLRH 190
+ + R LG G F V+L + K +ALKV+ AQ E A E +L + V +S +
Sbjct: 324 YHVIRKLGWGHFSTVWLCWDLTCKRFVALKVVKSAQHYTETALDEVKLLKCVR-ESDVAD 500
Query: 191 PNILRLYGYFHD-------ATRVYLILEYAPLGTVYRELQKLSKFDEQRTATY-----IT 238
P + D T V ++ E LG Y L+ + + + Q + I
Sbjct: 501 PARAKCVQLLDDFKISGVNGTHVAMVFEV--LG--YNLLKLIIRSNYQGIPIHNVKLIIR 668
Query: 239 ELANALSYCHSK-RVIHRDIKPENLLL 264
++ LSY H+K R+IH DIKPEN+L+
Sbjct: 669 QVLEGLSYMHAKCRIIHTDIKPENILI 749
>18481
Length = 437
Score = 44.7 bits (104), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 38/119 (31%), Positives = 57/119 (47%), Gaps = 7/119 (5%)
Frame = -1
Query: 167 AQLEKAGVEHQL-RREVEIQSHL-RHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQK 224
++E V+HQL E ++ + RHP + +Y Y + L++E LG EL
Sbjct: 395 VKIEAIDVKHQLLHYEAKVYEQIGRHPGLPTMYHYGTEKHFNALVME--LLGPSLEELFV 222
Query: 225 LSK--FDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLG---SAGELKIADFGWS 278
+ K F + +L + L + H K IHRD+KP+N L+G L I DFG S
Sbjct: 221 ICKRRFTLKTILMVSDQLLSRLEFIHQKCFIHRDLKPDNFLMGLGRHCHRLYIIDFGLS 45
>32957
Length = 645
Score = 44.7 bits (104), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 20/60 (33%), Positives = 32/60 (53%)
Frame = +3
Query: 275 FGWSVHAPSSRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTY 334
F V R T CGT +Y+ PE+ E + + ++VD W LG+L +E L + ++ Y
Sbjct: 3 FALCVEKSGGRTRTFCGTREYMAPEVHERKEYGKEVDWWGLGILLHELLAAQIKKHSSCY 182
>31489
Length = 329
Score = 43.9 bits (102), Expect = 1e-04, Method: Composition-based stats.
Identities = 23/88 (26%), Positives = 43/88 (48%), Gaps = 6/88 (6%)
Frame = +3
Query: 182 VEIQSHLRHPNI------LRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTAT 235
++I H +H NI L+ +HD ++++ + ++R + E+
Sbjct: 3 IKILKHFKHDNIISIREILKPKDSYHDFKDIHVVFDLME-SDLHRIIYSDQPLTEEHIRY 179
Query: 236 YITELANALSYCHSKRVIHRDIKPENLL 263
++ ++ L Y HS V+HRD+KP NLL
Sbjct: 180 FLYQILRGLKYIHSANVVHRDLKPSNLL 263
>16708
Length = 1397
Score = 43.9 bits (102), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 64/266 (24%), Positives = 100/266 (37%), Gaps = 33/266 (12%)
Frame = -1
Query: 139 LGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNIL-RLY 197
LGKG FG VY AR L KA L+ + + H EVE + L +++
Sbjct: 1379 LGKGVFGKVYEAR--------LLSTHEKAALKTSILCHHSLDEVEALGRIEGGFYLAQMF 1224
Query: 198 GY------FHDATRVYLILEYAPLGTVYRELQK----LSKFDEQRTATYITELANALSYC 247
G F + E PL VY + + + + AL +
Sbjct: 1223 GAWVTCLPFPKMNILLHFYEMGPLCNVYAHYKNKEMPIRWSNPAMVCCIAGQXVCALEHI 1044
Query: 248 HSKRVIHRDIKPENLLLGSAGELKIADFG----WSVH-APSSRRTTLCG---TLDYLPPE 299
H V+H D+K +N+L+ + G K+ D+G + V+ AP+ ++ C T PP
Sbjct: 1043 HELGVVHMDVKADNVLVDAHGNCKLTDYGIAQLYKVYPAPTETHSSGCTNKRTFYTRPPA 864
Query: 300 -MIEGRMHDEKVD------------LWSL-GVLCYEFLVGKPPFEANTYQETYKRISRVE 345
M E+ D LW+L G + V +PP + + R E
Sbjct: 863 TMTPSERFSEEGDGIGTDYFRLGQMLWTLTGAVLLHVWVSRPPKLPD-----WCRTPESE 699
Query: 346 FTFPDFVTEGARDLISRLLKHNPSQR 371
+ G D I +L +P+ R
Sbjct: 698 LS-------GMSDFIEKLCHGDPNMR 642
>17253
Length = 483
Score = 43.9 bits (102), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 27/112 (24%), Positives = 53/112 (47%), Gaps = 13/112 (11%)
Frame = -1
Query: 180 REVEIQSHL-RHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQK--------LSKFDE 230
RE+ I L RHPN++ G + +++E+ G + L+K L+
Sbjct: 402 RELSIMRKLPRHPNVVSFMGCCTMSDPALILMEFCCHGDLLSFLRKRRPDRTVFLTSTAN 223
Query: 231 QRTA----TYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS 278
TA ++ +A +++ + +++HRD+ N+L+ K++DFG S
Sbjct: 222 DLTARDFFSFALHVARGMAHVANNKIVHRDVAARNVLISERNVCKVSDFGLS 67
>20640
Length = 1492
Score = 43.5 bits (101), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 38/144 (26%), Positives = 65/144 (45%), Gaps = 5/144 (3%)
Frame = +1
Query: 253 IHRDIKPENLLLGSAGELKIADFGW--SVHAPSSRRTTLCGT--LDYLPPEMIEGRMHDE 308
+HRD+ N L+G +KI+DFG SVH+ R + + ++P E I
Sbjct: 10 VHRDLATRNCLVGHDLVVKISDFGLARSVHSVDYYRGSEHDAIPIRWMPLEAILYNKFST 189
Query: 309 KVDLWSLGVLCYE-FLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHN 367
+ D+WS GV+ +E F P+ T++E + FV EG ++L
Sbjct: 190 QSDVWSFGVVLWEIFAFALQPYYGLTHEEVVR-----------FVKEG------KVLACP 318
Query: 368 PSQRPMLREVLEHPWITANSSKPS 391
P + E+++ W +++PS
Sbjct: 319 ERTPPPMYELMKQCWHRRPATRPS 390
>07836
Length = 1478
Score = 42.7 bits (99), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 49/195 (25%), Positives = 85/195 (43%), Gaps = 31/195 (15%)
Frame = -1
Query: 159 LALKVLFKAQLEKAGVEHQLRREVEIQSH--LRHPNILRLYGY----FHDATRVYLILEY 212
+A+K+ F + E RE E+ LRH NIL T+++LI +Y
Sbjct: 1469 VAVKIFFTTE------EASWFRETELYQTVLLRHENILGFIAADIKGTGSWTQLFLITDY 1308
Query: 213 APLGTVYRELQKLSK-FDEQRTATYITELANALSYCHSK--------RVIHRDIKPENLL 263
G+++ L LS+ D L++ H + + HRDIK +N+L
Sbjct: 1307 HENGSLHDYL--LSRVLDSSEMLALAHSAICGLAHLHIEIFGTRGKPAIAHRDIKSKNIL 1134
Query: 264 LGSAGELKIADFGWSVH----------APSSRRTTLCGTLDYLPPEMIEGRMHD------ 307
+ G IAD G +V AP+ R+ GT Y+ PE++E ++
Sbjct: 1133 VKKNGTCCIADLGLAVRYISESNEVDVAPNPRQ----GTKRYMAPEVLEMLLNVKNFDAF 966
Query: 308 EKVDLWSLGVLCYEF 322
++ D+++ G++ +E
Sbjct: 965 KQADMYAFGLVMWEI 921
>20559
Length = 430
Score = 39.7 bits (91), Expect(2) = 3e-04, Method: Compositional matrix adjust.
Identities = 22/81 (27%), Positives = 45/81 (55%)
Frame = -2
Query: 130 LEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLR 189
++ +E +G+G +G V+ A+ +++ I+ALK + + + GV RE+ + L+
Sbjct: 378 MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRV-RLDDDDEGVPSSALREICLLKELK 202
Query: 190 HPNILRLYGYFHDATRVYLIL 210
H NI+RL+ H ++ L+
Sbjct: 201 HRNIVRLHDVLHSERKLTLVF 139
Score = 21.9 bits (45), Expect(2) = 3e-04, Method: Compositional matrix adjust.
Identities = 7/12 (58%), Positives = 9/12 (75%)
Frame = -1
Query: 244 LSYCHSKRVIHR 255
L +CHS V+HR
Sbjct: 37 LVFCHSNNVLHR 2
>17300
Length = 480
Score = 42.0 bits (97), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 29/98 (29%), Positives = 46/98 (46%), Gaps = 7/98 (7%)
Frame = +1
Query: 253 IHRDIKPENLLLGSAGELKIADFGWSVHAPSSRR----TTLCGTL--DYLPPEMIEGRMH 306
+HRD+ N+L+ K+ADFG S S TT G + + PE I R
Sbjct: 40 VHRDLAARNILVNEILVCKVADFGLSREIESDTTEGAYTTKGGKIPVRWTAPEAIAYRKF 219
Query: 307 DEKVDLWSLGVLCYEFL-VGKPPFEANTYQETYKRISR 343
D+WS GV+ +E + G+ P+ + Q+ K + +
Sbjct: 220 TSASDVWSFGVVMWEVMSYGERPYWNWSNQDVIKAVEK 333
>11404
Length = 563
Score = 40.8 bits (94), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 42/150 (28%), Positives = 71/150 (47%), Gaps = 12/150 (8%)
Frame = +1
Query: 127 QWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKV-------LFKAQLEKAGVEHQLR 179
+WA + +EI +GKG FG V A + +A+K+ L +AQ+E +E R
Sbjct: 130 KWA-DRYEIDSLIGKGSFGQVVKAYDHTDNEQVAIKIIKNKKPFLNQAQIEVKLLEMMNR 306
Query: 180 REVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKF---DEQRTATY 236
+ + + + I+RL +F R +L L + L +L + + F T +
Sbjct: 307 HDTDNKYY-----IVRLKRHF--MFRSHLCLVFELLSYNLYDLLRNTNFRGVSLNLTRKF 465
Query: 237 ITELANALSYCHS--KRVIHRDIKPENLLL 264
+L AL + + +IH D+KPEN+LL
Sbjct: 466 AQQLCTALLFLATPEMSIIHCDLKPENILL 555
>21210
Length = 518
Score = 40.4 bits (93), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 27/106 (25%), Positives = 49/106 (46%), Gaps = 13/106 (12%)
Frame = +3
Query: 291 GTLDYLPPEMIEGRM----HDEKVDLWSLGVLCYEFLVGKPPFE--ANTYQETYKRISRV 344
G Y+ PE I+ R +D + D+WSLG+ E G+ P+ + + + + + V
Sbjct: 6 GCRPYMAPERIDPRASSHGYDVRSDVWSLGITLMELATGRFPYRKWVSIFDQLQQVVRGV 185
Query: 345 EFTFP-------DFVTEGARDLISRLLKHNPSQRPMLREVLEHPWI 383
P DFV + +++ L + QRP ++L HP++
Sbjct: 186 APCLPHDGAFSHDFV-----NFVNKCLTKDEKQRPKYNKLLAHPFV 308
>21418
Length = 831
Score = 39.7 bits (91), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 20/56 (35%), Positives = 32/56 (57%), Gaps = 4/56 (7%)
Frame = +2
Query: 339 KRISRVEFTFPD----FVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKP 390
KRI ++ FPD V++ A+DLI +L +PS+R + +VL + WI + P
Sbjct: 8 KRIRSGQYDFPDPEWTNVSQAAKDLIKGMLNVDPSKRLCIEDVLRNKWIAQYDAVP 175
>20160
Length = 1277
Score = 38.5 bits (88), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 15/33 (45%), Positives = 24/33 (72%)
Frame = +2
Query: 354 EGARDLISRLLKHNPSQRPMLREVLEHPWITAN 386
E A DLI+R + +PS RP+L ++L+H W+T +
Sbjct: 332 EDAADLINRCIALDPSTRPVLADILKHKWMTKD 430
>00638
Length = 1595
Score = 38.1 bits (87), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 15/37 (40%), Positives = 21/37 (56%)
Frame = +2
Query: 223 QKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKP 259
Q F + Y+ EL AL +CHS ++HRD+KP
Sbjct: 392 QLYQTFTDYDIRFYLYELMKALDFCHSMGIMHRDVKP 502
>31789
Length = 676
Score = 36.6 bits (83), Expect = 0.018, Method: Compositional matrix adjust.
Identities = 27/103 (26%), Positives = 45/103 (43%), Gaps = 5/103 (4%)
Frame = +2
Query: 132 DFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHP 191
D EIGR G F VY + + +A L + K + + E E+ L+HP
Sbjct: 335 DVEIGR----GSFKTVYKGLDTELGVAVAWCELQDKKWNKT-ERQRFKEEAEMLKELQHP 499
Query: 192 NILRLYGYFHDATR-----VYLILEYAPLGTVYRELQKLSKFD 229
NI+R + Y+ + + L+ E GT+ L++ K +
Sbjct: 500 NIVRFFDYWEEHNHRNRKVIILVTELMTSGTLKTYLKRFKKIN 628
>36002
Length = 253
Score = 36.2 bits (82), Expect = 0.023, Method: Compositional matrix adjust.
Identities = 21/66 (31%), Positives = 31/66 (46%), Gaps = 5/66 (7%)
Frame = +1
Query: 324 VGKPPFEANTYQET-YKRISRVEFTFPDF----VTEGARDLISRLLKHNPSQRPMLREVL 378
V +P QE + RI + FP ++ A+DLI LL P +R +VL
Sbjct: 16 VAEPGEACQDCQELLFNRIQDGNYFFPSMEWSAISSSAKDLIRHLLVREPRKRYSAADVL 195
Query: 379 EHPWIT 384
+HPW+
Sbjct: 196 KHPWVC 213
>37063
Length = 455
Score = 35.4 bits (80), Expect = 0.043, Method: Compositional matrix adjust.
Identities = 23/77 (29%), Positives = 41/77 (53%), Gaps = 15/77 (19%)
Frame = -2
Query: 257 IKPENLLLGSAGE---LKIADF----GWSVHAPSSRRTTL---CGTLDYLPPEMIEGRM- 305
+KPEN+L E LKI DF G + ++ L G+ +Y+ PE+++ +
Sbjct: 454 LKPENILCEHLDEVVPLKICDFDLASGINCDGDGTKTPELLTPVGSAEYMAPEVVDAWVG 275
Query: 306 ----HDEKVDLWSLGVL 318
+D++ D+WSLG++
Sbjct: 274 ESFSYDKRCDMWSLGII 224
>20655
Length = 1181
Score = 34.7 bits (78), Expect = 0.068, Method: Compositional matrix adjust.
Identities = 17/56 (30%), Positives = 31/56 (55%), Gaps = 4/56 (7%)
Frame = +2
Query: 339 KRISRVEFTFP----DFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKP 390
KRI ++ FP V++ A+DLI +L +P +R +++V+ W+ N+ P
Sbjct: 8 KRIRNGQYEFPKPEWSRVSQDAKDLIRGMLCTDPDKRLNIKQVMASKWVADNTMVP 175
>00394
Length = 548
Score = 34.7 bits (78), Expect = 0.079, Method: Compositional matrix adjust.
Identities = 23/94 (24%), Positives = 43/94 (45%), Gaps = 5/94 (5%)
Frame = -2
Query: 137 RPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRL 196
+ +G+G F VY + + +A L + KA + + E E+ L+HPNI+R
Sbjct: 280 KEIGRGSFKTVYKGLDTELGVAVAWCELQDKKWNKAE-RQRFKEEAEMLKELQHPNIVRF 104
Query: 197 YGYFHDATR-----VYLILEYAPLGTVYRELQKL 225
+ Y+ + + L+ E GT+ L++
Sbjct: 103 FDYWEEHNHRNRKVIILVTELMTSGTLKTYLKRF 2
>18401
Length = 463
Score = 32.7 bits (73), Expect = 0.26, Method: Compositional matrix adjust.
Identities = 16/63 (25%), Positives = 29/63 (46%)
Frame = -3
Query: 287 TTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEF 346
+T+ T Y PE+I D+WS+G + +E G F+ + +E + R+
Sbjct: 458 STIVSTRHYRAPEVILELGWSHPCDVWSVGCIMFELYTGYTLFQTHDNKEHLAMMERILG 279
Query: 347 TFP 349
+ P
Sbjct: 278 SLP 270
>20773
Length = 391
Score = 32.0 bits (71), Expect = 0.48, Method: Compositional matrix adjust.
Identities = 17/54 (31%), Positives = 28/54 (51%)
Frame = -1
Query: 330 EANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWI 383
+ + ++R SR F VT+ +L+ RLL ++PSQR L HP++
Sbjct: 388 SGSCWSGLHRRRSRPVFPHTTVVTQHFYNLVQRLLTYDPSQRLTPDLALSHPFV 227
>21800
Length = 855
Score = 32.0 bits (71), Expect = 0.49, Method: Compositional matrix adjust.
Identities = 17/46 (36%), Positives = 26/46 (56%), Gaps = 5/46 (10%)
Frame = +2
Query: 237 ITELANALSYCHSK-RVIHRDIKPENLLLGSAG----ELKIADFGW 277
I ++ L+Y H+K +IH DIKPEN+L+ +L + F W
Sbjct: 650 IRQVLEGLNYLHAKCNIIHTDIKPENILICVDDNYIRKLAVDAFEW 787
>36481
Length = 806
Score = 32.0 bits (71), Expect = 0.51, Method: Compositional matrix adjust.
Identities = 32/141 (22%), Positives = 65/141 (46%), Gaps = 8/141 (5%)
Frame = +2
Query: 132 DFEIGRPLGKGKFGNVYLAREKQSKFILALKVL--FKAQLEKAGVE-HQLRREVEIQSHL 188
D ++ G+G FG V ++ +ALK++ E A +E + L + E H
Sbjct: 365 DMKLCPHWGEGTFGKVVQCKDLLKGDDIALKIIKNVDKYREAAKLEINVLEKLREKDPHA 544
Query: 189 RHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKF-----DEQRTATYITELANA 243
+H + L + + ++ + + LG + K + + ++ R +Y +L A
Sbjct: 545 KHMCVQMLDWFDYHG---HVCISFHMLGLSVFDFLKDNSYGAYPIEQVRHISY--QLCYA 709
Query: 244 LSYCHSKRVIHRDIKPENLLL 264
+++ H ++ H D+KPEN+L
Sbjct: 710 VNFLHENQLTHTDLKPENILF 772
>19872
Length = 446
Score = 31.6 bits (70), Expect = 0.53, Method: Compositional matrix adjust.
Identities = 14/41 (34%), Positives = 25/41 (60%), Gaps = 4/41 (9%)
Frame = +3
Query: 349 PDFVTEGA----RDLISRLLKHNPSQRPMLREVLEHPWITA 385
PDF + L+ ++L H+P+QRP R++L+ P++ A
Sbjct: 99 PDFTKDADLHNQSALLRQMLSHDPTQRPSSRDLLQSPYLPA 221
>17932
Length = 597
Score = 28.1 bits (61), Expect(2) = 0.76, Method: Compositional matrix adjust.
Identities = 14/31 (45%), Positives = 16/31 (51%), Gaps = 2/31 (6%)
Frame = -2
Query: 313 WSLGVLCYEFLVGKPPF--EANTYQETYKRI 341
WSLGV YE L G PF + + TY I
Sbjct: 593 WSLGVCAYEMLFGCTPFTDDDGSMVATYNNI 501
Score = 21.6 bits (44), Expect(2) = 0.76, Method: Compositional matrix adjust.
Identities = 14/32 (43%), Positives = 20/32 (62%)
Frame = -3
Query: 352 VTEGARDLISRLLKHNPSQRPMLREVLEHPWI 383
V++ ARDLIS+LL S R E+ +HP+
Sbjct: 460 VSKEARDLISQLLSDGKS-RLGWPELQQHPFF 368
>16350
Length = 1108
Score = 29.6 bits (65), Expect = 2.1, Method: Compositional matrix adjust.
Identities = 12/39 (30%), Positives = 23/39 (58%), Gaps = 1/39 (2%)
Frame = +3
Query: 358 DLISRLLKHNPSQRPMLREVLEHPWITANS-SKPSNCQN 395
D ++ +L+ +P QR + L+HPW+ ++ +PS Q
Sbjct: 762 DFLAPMLEFDPEQRATAAQSLQHPWLKLDA*PEPSGSQQ 878
>20513
Length = 405
Score = 29.3 bits (64), Expect = 2.9, Method: Compositional matrix adjust.
Identities = 12/39 (30%), Positives = 23/39 (58%), Gaps = 1/39 (2%)
Frame = -1
Query: 358 DLISRLLKHNPSQRPMLREVLEHPWITANS-SKPSNCQN 395
D ++ +L+ +P QR + L+HPW+ ++ +PS Q
Sbjct: 282 DFLAPMLEFDPEQRATAAQSLQHPWLKLDA*PEPSGSQQ 166
>17644
Length = 463
Score = 27.7 bits (60), Expect = 8.1, Method: Compositional matrix adjust.
Identities = 13/32 (40%), Positives = 19/32 (59%)
Frame = +3
Query: 352 VTEGARDLISRLLKHNPSQRPMLREVLEHPWI 383
VT+ BL+ RLL ++PSQR L HP++
Sbjct: 69 VTQHFYBLVQRLLTYDPSQRLTPDLALSHPFV 164
>18929
Length = 440
Score = 27.7 bits (60), Expect = 9.8, Method: Compositional matrix adjust.
Identities = 11/38 (28%), Positives = 22/38 (57%)
Frame = +1
Query: 348 FPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITA 385
F + ++ + +I R++ +P QRP ++L HP + A
Sbjct: 34 FINTISVELQQVIRRMMSPDPRQRPTANQLLAHPTLAA 147
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000379251 | hsapiens_gene_ensembl |
Serine/threonine-protein kinase 6 (EC 2.7.11.1) (Aurora kinase A)
(Aurora-A) (Serine/threonine kinase 15) (Aurora/IPL1-related kinase 1)
(Aurora-related kinase 1) (hARK1) (Breast-tumor-amplified kinase).
[Source:Uniprot/SWISSPROT;Acc:O14965]
(403 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
21433 184 3e-69
15910 120 8e-28
03240 119 2e-27
01060 117 6e-27
00300 114 8e-26
30755 110 1e-24
18484 110 1e-24
18921 107 7e-24
12721 105 4e-23
14420 101 5e-22
01707 99 3e-21
14126 98 5e-21
09606 97 8e-21
06405 97 9e-21
09007 94 8e-20
13592 93 2e-19
13212 92 3e-19
01392 91 1e-18
01756 87 1e-17
13066 87 1e-17
11780 80 2e-17
04591 86 2e-17
01718 86 3e-17
17975 85 4e-17
31885 84 7e-17
27546 83 2e-16
00486 82 3e-16
21079 82 6e-16
00392 80 1e-15
01966 79 3e-15
19761 76 2e-14
19094 70 6e-14
26560 75 7e-14
29581 72 4e-13
20152 69 3e-12
27405 68 7e-12
26711 66 3e-11
19301 65 5e-11
38560 65 6e-11
14477 64 1e-10
04852 64 1e-10
06358 64 1e-10
04138 64 2e-10
21808 63 2e-10
00715 62 5e-10
14116 61 6e-10
28157 61 8e-10
12672 61 9e-10
07940 61 1e-09
03508 61 1e-09
26009 41 3e-09
12786 59 3e-09
18663 58 7e-09
28638 56 3e-08
02638 53 2e-07
11185 52 3e-07
25019 52 4e-07
29590 39 1e-06
27274 50 2e-06
31120 49 4e-06
37602 49 4e-06
07833 48 6e-06
32000 48 6e-06
07291 48 8e-06
01106 47 2e-05
18481 45 6e-05
32957 45 6e-05
31489 44 1e-04
16708 44 1e-04
17253 44 1e-04
20640 44 1e-04
07836 43 3e-04
20559 40 3e-04
17300 42 4e-04
11404 41 0.001
21210 40 0.001
21418 40 0.002
20160 39 0.006
00638 38 0.006
31789 37 0.018
36002 36 0.023
37063 35 0.043
20655 35 0.068
00394 35 0.079
18401 33 0.26
20773 32 0.48
21800 32 0.49
36481 32 0.51
19872 32 0.53
17932 28 0.76
16350 30 2.1
20513 29 2.9
17644 28 8.1
18929 28 9.8
>21433
Length = 590
Score = 184 bits (467), Expect(2) = 3e-69, Method: Compositional matrix adjust.
Identities = 93/136 (68%), Positives = 107/136 (78%)
Frame = +2
Query: 231 QRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLC 290
+RTA YI +L++AL YCH ++VIHRDIKPENLLLG G+LKIADFGWSVHAPSSRRTT+C
Sbjct: 167 KRTACYIYQLSSALEYCHYRKVIHRDIKPENLLLGLKGDLKIADFGWSVHAPSSRRTTMC 346
Query: 291 GTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPD 350
GTLDYLPPEM+EG+ HDE VDLWSLGVLCYEFLVG PP + + R P
Sbjct: 347 GTLDYLPPEMVEGKTHDENVDLWSLGVLCYEFLVGTPPLRPSPTRPPTPASPRWTSGSPS 526
Query: 351 FVTEGARDLISRLLKH 366
VT GARDLIS+LL+H
Sbjct: 527 IVTPGARDLISKLLRH 574
Score = 95.9 bits (237), Expect(2) = 3e-69, Method: Compositional matrix adjust.
Identities = 44/64 (68%), Positives = 54/64 (84%), Gaps = 1/64 (1%)
Frame = +3
Query: 176 HQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDE-QRTA 234
HQLRRE+EIQSHLRH NILR++GYFHD TRVYLILE+AP G +Y+ELQ+ KFDE ++ A
Sbjct: 3 HQLRREIEIQSHLRHDNILRMFGYFHDKTRVYLILEFAPKGELYKELQRCHKFDENEQHA 182
Query: 235 TYIT 238
Y +
Sbjct: 183 IYTS 194
>15910
Length = 1361
Score = 120 bits (302), Expect = 8e-28, Method: Compositional matrix adjust.
Identities = 61/177 (34%), Positives = 104/177 (58%), Gaps = 8/177 (4%)
Frame = +2
Query: 226 SKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLL---LGSAGELKIADFGWS-VHA 281
++ E+ A I+++ + + Y H+ V+HRD+KPENLL + +LK+ADFG S +
Sbjct: 449 GQYTEKDAARAISDILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLADFGLSRIIE 628
Query: 282 PSSRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRI 341
P + +T+CGT Y PE+++G + VD+WS+GV+ Y L G PF A E Y++I
Sbjct: 629 PEVQMSTVCGTPGYCAPEVLKGDKYTPSVDMWSVGVIAYILLCGYEPFFAENEFEMYRKI 808
Query: 342 SRVEFTFPD----FVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQ 394
+ E+ F + ++E A+D++ +LL +P +R E L PW+ ++K +N +
Sbjct: 809 IKGEYKFDEEYWSEISENAKDVVRKLLVIDPKKRLTATEALRLPWVKGVATKTTNME 979
>03240
Length = 1683
Score = 119 bits (298), Expect = 2e-27, Method: Compositional matrix adjust.
Identities = 86/283 (30%), Positives = 133/283 (46%), Gaps = 52/283 (18%)
Frame = -3
Query: 133 FEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPN 192
FE + LG G FG V L R+ + + A+K L K+ + K ++ E +I + +
Sbjct: 1285 FEKIKTLGVGAFGEVSLCRKNDTGMLYAMKTLRKSDVLKRNQVAHVKAERDILAEADNEW 1106
Query: 193 ILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRV 252
+++LY F D +Y +++Y P G + L ++ DE Y+ EL A+ H
Sbjct: 1105 VVKLYYSFQDHNYLYFVMDYVPGGDLMGLLIRMEILDEPLARFYVAELVQAIESVHRMGF 926
Query: 253 IHRDIKPENLLLGSAGELKIADFG------WS----------VHA--------------- 281
IHRDIKP+N+L+ G +K+ DFG W+ HA
Sbjct: 925 IHRDIKPDNILIDRNGHIKLTDFGLCTGFRWTHNSKYYQRDGTHARQDSMEVKCQLDEQC 746
Query: 282 ------PSSRRT---------TLCGTLDYLPPEMIEGRM--HDEKVDLWSLGVLCYEFLV 324
P RR +L GT +Y+ PE++ R+ + D WS+GV+ +E LV
Sbjct: 745 QCEILKPLERRRKREQRCLAHSLVGTPNYIAPEVL-SRLGGYTSVCDWWSVGVILFEMLV 569
Query: 325 GKPPFEANTYQET-YKRIS---RVEFTFPDFVTEGARDLISRL 363
G PPF ANT ET YK I+ ++ +++ A+DLI RL
Sbjct: 568 GHPPFYANTPAETQYKVINWKDMLKIPRESNLSQPAKDLILRL 440
>01060
Length = 1800
Score = 117 bits (294), Expect = 6e-27, Method: Compositional matrix adjust.
Identities = 83/305 (27%), Positives = 145/305 (47%), Gaps = 36/305 (11%)
Frame = +1
Query: 129 ALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHL 188
AL D + +G+G +G VY R + + LA+K + + + + GV RE+ + L
Sbjct: 67 ALSDLTDFQKIGEGTYGVVYKCRHRATGRKLAMKKI-RLRGSEDGVPSSAIREIAMLREL 243
Query: 189 RHPNILRLYGYFHDATRVYLILEY--APLGTVYRELQKLSKFDEQRTATYITELANALSY 246
RH NI+ L + R++L+ E+ L + + D + +Y+ ++ + +
Sbjct: 244 RHTNIVCLEDVIMEDERLFLVFEFLSMDLKMYIDKFPEGVVLDRRLVKSYVFQIVTGIXF 423
Query: 247 CHSKRVIHRDIKPENLLLGSAGELKIADFGW--SVHAPSSRRTTLCGTLDYLPPEMIEG- 303
CH +R++HRD+KP+NLL+ G +KIADFG + P T TL Y PE++ G
Sbjct: 424 CHQRRIVHRDLKPQNLLINHTGAIKIADFGMARTFALPVRAYTHEVVTLWYRAPEILMGA 603
Query: 304 RMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRV-----EFTFPDF------- 351
+ VD+WS+G + + L+ P F+ ++ + +I R+ E T+P+F
Sbjct: 604 SKYSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKLPAFN 783
Query: 352 -----------------VTEGARDLISRLLKHNPSQRPMLREVLEHPWI--TANSSKPSN 392
+ DLI R LK +P+QR +++L+H + S KP +
Sbjct: 784 GMFPLWKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYFLNVDTSVKPVD 963
Query: 393 CQNKE 397
+ E
Sbjct: 964 VPSPE 978
>00300
Length = 2318
Score = 114 bits (285), Expect = 8e-26, Method: Compositional matrix adjust.
Identities = 74/257 (28%), Positives = 125/257 (48%), Gaps = 10/257 (3%)
Frame = -1
Query: 136 GRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILR 195
G +G+G+FG VY A + ++ALK + K Q ++ E++I ++H N+++
Sbjct: 1643 GNKIGEGQFGKVYTAVNMSTGELMALKEM-KFQPNDLQQLREMCDEIKIFEGIQHENLVK 1467
Query: 196 LYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHR 255
YG + + +EY GT+ E K+ E Y E+ A+++ H ++HR
Sbjct: 1466 YYGVEVHKDEMLMFMEYCDTGTI-EEAAKMG-LPEYLIRRYTREIVLAVNHLHENSIVHR 1293
Query: 256 DIKPENLLLGSAGELKIADFGWSVHAPSSRRT-----TLCGTLDYLPPEMI---EGRMHD 307
DIK N+ L S G +K+ DFG SV S L GT Y+ PE+ + +
Sbjct: 1292 DIKGANIFLTSNGHVKLGDFGCSVKLKSHTTMPGEFHNLVGTTAYMAPEVFTQNDQGGYG 1113
Query: 308 EKVDLWSLGVLCYEFLVGKPPFE--ANTYQETYKRISRVEFTFPDFVTEGARDLISRLLK 365
D+WSLG + E GK P+ N YQ YK + PD ++ + + ++
Sbjct: 1112 RAADIWSLGCVVIEMATGKRPWHDLDNNYQIMYKVGIGHKPAVPDSLSVEGKHFLDLIMC 933
Query: 366 HNPSQRPMLREVLEHPW 382
H+P+QR + ++L+H +
Sbjct: 932 HDPAQRALASQLLDHTF 882
>30755
Length = 1137
Score = 110 bits (275), Expect = 1e-24, Method: Compositional matrix adjust.
Identities = 60/165 (36%), Positives = 91/165 (55%), Gaps = 7/165 (4%)
Frame = +2
Query: 228 FDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRT 287
F E+RT Y E+ +AL Y HS+ +I+RD+K ENLLL G +K+ADFG + RT
Sbjct: 23 FTEERTRFYGAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCKEDITYGRT 202
Query: 288 T--LCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVE 345
T CGT +YL PE+++ + VD W GV+ YE + G+ PF + + I +
Sbjct: 203 TKTFCGTPEYLAPEVLDDNDYGRAVDWWGTGVVMYEMICGRLPFYNRDHDVLFTLILVED 382
Query: 346 FTFPDFVTEGARDLISRLLKHNPSQR-----PMLREVLEHPWITA 385
FP +T+ A+ L+S LL +P R ++E+ HP+ +
Sbjct: 383 VKFPRNITDEAKSLLSGLLAKDPRNRLGGGQDDVKEIQAHPFFAS 517
>18484
Length = 635
Score = 110 bits (275), Expect = 1e-24, Method: Compositional matrix adjust.
Identities = 57/156 (36%), Positives = 89/156 (57%), Gaps = 2/156 (1%)
Frame = +1
Query: 218 VYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGW 277
+YR +Q+ KF E A Y E+A L + H + +I+RD+K +N++L S G +KIADFG
Sbjct: 7 MYR-IQQEGKFKEPVAAFYAAEIAVGLFFLHDQGIIYRDLKLDNVMLDSEGHIKIADFGM 183
Query: 278 SVHAPSSRRTT--LCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQ 335
+ TT CGT DY+ PE++ + + + VD W+ GVL +E L G+PPF+
Sbjct: 184 CKEGMTGDATTRTFCGTPDYIAPEIVLYQPYSKSVDWWAYGVLLFEMLAGQPPFDGEDED 363
Query: 336 ETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQR 371
E + I+ ++P ++ A L LL NP++R
Sbjct: 364 ELFSSITDHNVSYPKAMSREAVSLCKGLLMKNPTKR 471
>18921
Length = 697
Score = 107 bits (268), Expect = 7e-24, Method: Compositional matrix adjust.
Identities = 64/199 (32%), Positives = 109/199 (54%), Gaps = 3/199 (1%)
Frame = +2
Query: 133 FEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPN 192
F+I LG+G +G+V+ + K++ +LA+K Q+ ++ +E+ I
Sbjct: 35 FDILGKLGEGSYGSVFKSLHKETGQVLAIK-----QVPVDTDLQEIIKEISIMQQCDSKY 199
Query: 193 ILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSK-FDEQRTATYITELANALSYCHSKR 251
I++ YG + T +++++EY G+V ++ +K E+ AT + L Y HS+R
Sbjct: 200 IVKYYGSYFKNTDLWIVMEYCGAGSVSDIMRLRNKTLVEREIATILYYTLKGLXYLHSRR 379
Query: 252 VIHRDIKPENLLLGSAGELKIADFGWS--VHAPSSRRTTLCGTLDYLPPEMIEGRMHDEK 309
IHRDIK N+LL + G K+ADFG + + ++R T+ GT ++ PE+I+ +D
Sbjct: 380 KIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTPYWMAPEVIQEIGYDCV 559
Query: 310 VDLWSLGVLCYEFLVGKPP 328
D+WSLG+ E GKPP
Sbjct: 560 ADIWSLGITALEMAEGKPP 616
>12721
Length = 821
Score = 105 bits (261), Expect = 4e-23, Method: Compositional matrix adjust.
Identities = 69/247 (27%), Positives = 123/247 (49%), Gaps = 5/247 (2%)
Frame = +1
Query: 130 LEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLR 189
L+DF +G+G G V +A + + +A+K K L K L EV +
Sbjct: 94 LDDF---MKIGEGSTGIVCIATSRDGR-QMAVK---KMDLRKQQRRELLFNEVVVMRDYH 252
Query: 190 HPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHS 249
HPNI+ +Y + +++++E+ G ++ ++ DE + AT AL++ H+
Sbjct: 253 HPNIVEMYNSYLVNDELWVVMEFME-GGALTDIVTNNRMDEVQIATVCRACLKALAFLHA 429
Query: 250 KRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSS--RRTTLCGTLDYLPPEMIEGRMHD 307
VIHRDIK +++LL G++K+ DFG+ +R +L GT ++ PE+I +
Sbjct: 430 NGVIHRDIKSDSILLSHDGKVKLXDFGFCAQVTQDLQKRKSLVGTPYWMAPEVISRLPYG 609
Query: 308 EKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRV---EFTFPDFVTEGARDLISRLL 364
+VD+WSLG++ E + +PPF + +RI + + ++ + I R+L
Sbjct: 610 PEVDIWSLGIMVMEMIDAEPPFFNEPPLQAMRRIRDMPPPKLRNTHKISPRLQGFIDRML 789
Query: 365 KHNPSQR 371
+P QR
Sbjct: 790 VRDPHQR 810
>14420
Length = 528
Score = 101 bits (252), Expect = 5e-22, Method: Compositional matrix adjust.
Identities = 48/151 (31%), Positives = 87/151 (57%), Gaps = 2/151 (1%)
Frame = +2
Query: 181 EVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITEL 240
E+ + ++PNI+ + +++++E+ G++ + + + DE + A E
Sbjct: 50 EILVMRENQNPNIVNYLDSYLVGEELWVVMEFLAGGSLTDVVTE-TCMDEGQIAAVCREC 226
Query: 241 ANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAP--SSRRTTLCGTLDYLPP 298
AL + H +VIHRDIK +N+LLG G +K+ DFG+ S+R+T+ GT ++ P
Sbjct: 227 LQALEFLHENQVIHRDIKSDNILLGMDGSVKLTDFGFCAQLSPEQSKRSTMVGTPYWMAP 406
Query: 299 EMIEGRMHDEKVDLWSLGVLCYEFLVGKPPF 329
E++ + + VD+WSLGV+C E + G+PP+
Sbjct: 407 EVVTRKQYGPTVDIWSLGVMCIEMIEGEPPY 499
>01707
Length = 757
Score = 99.0 bits (245), Expect = 3e-21, Method: Compositional matrix adjust.
Identities = 58/201 (28%), Positives = 108/201 (53%), Gaps = 4/201 (1%)
Frame = +1
Query: 130 LEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLR 189
+E +E +G+G +G V+ R K++ ++A+K +++ + ++ RE+ + L+
Sbjct: 61 MEKYEKIGKIGEGSYGVVFKCRNKETSQLVAIKKFVESE-DDPLIKKIAMREIRMLKQLK 237
Query: 190 HPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSK-FDEQRTATYITELANALSYCH 248
HPN++RL F R++L+ +Y T+ EL + + E I + A+++CH
Sbjct: 238 HPNLVRLIEVFRRKKRLHLVFDYVD-HTLLNELDRYPRGLPEPMVKRIIYQTLLAVNFCH 414
Query: 249 SKRVIHRDIKPENLLLGSAGELKIADFGWS--VHAPSSRRTTLCGTLDYLPPEMIEGRM- 305
IHRD+KPEN+L+ G++K+ DFG++ + P T T Y PE++ G
Sbjct: 415 QYNTIHRDVKPENILITRQGQVKLCDFGFARILTGPGDEYTDYVATRWYRAPELLVGDTQ 594
Query: 306 HDEKVDLWSLGVLCYEFLVGK 326
+ VD+W++G + E L G+
Sbjct: 595 YGPPVDVWAIGCVFAELLTGQ 657
>14126
Length = 1265
Score = 98.2 bits (243), Expect = 5e-21, Method: Compositional matrix adjust.
Identities = 86/332 (25%), Positives = 146/332 (43%), Gaps = 46/332 (13%)
Frame = +3
Query: 116 SKQKNEESKKRQWALEDFEIGRPLGKGKFGNVYLARE--KQSKFILALKVLFKAQLEKAG 173
S+ + S++R + +E +G G +G VY AR+ Q +F+ ++ E G
Sbjct: 144 SESAAKMSRRRDSTEQKYEEVAVIGNGAYGTVYKARDLRNQGEFVAMKRIRLNNTEE--G 317
Query: 174 VEHQLRREVEIQSHLR---HPNILRLYGYFHDAT-----RVYLILEYA--PLGTVYRELQ 223
+ RE+ + L HPN++RL H+ R+ L+ EY L T Y
Sbjct: 318 MPMMAIREISMLKQLEQYEHPNVVRLLDVSHNTITDREIRLNLVFEYIEHDLAT-YLAKC 494
Query: 224 KLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS-VHAP 282
R + +L N + + HS R++HRD+KP+NLL+ G LK+ADFG + +++
Sbjct: 495 PSPGLGPDRIKDLMLQLLNGVDFLHSNRIVHRDLKPQNLLISKDGRLKLADFGLARIYSF 674
Query: 283 SSRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRIS 342
TT+ TL Y PE++ + VD+WS G + E + F+ ++ + K+I
Sbjct: 675 HMALTTVVVTLWYRSPEVLMQAEYGTSVDIWSCGCIFAELFTRRALFKGSSEFDQLKKIF 854
Query: 343 RV-----EFTFPDFVTEG----------------------ARDLISRLLKHNPSQRPMLR 375
V +P+ V+ A+DL+ ++L +R R
Sbjct: 855 EVIGLPPAGDWPEGVSVHRNSFRPTPPVPLQTLVPEMDPQAKDLMEKMLVFKSGRRISSR 1034
Query: 376 EVLEHPWITAN------SSKPSNCQNKESASK 401
E L HP++ + SS S +N S +
Sbjct: 1035ESLLHPYLRDDLDSIRTSSSLSTSENDSSDGR 1130
>09606
Length = 1300
Score = 97.4 bits (241), Expect = 8e-21, Method: Compositional matrix adjust.
Identities = 66/285 (23%), Positives = 126/285 (44%), Gaps = 34/285 (11%)
Frame = -3
Query: 130 LEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLR 189
+E+F + LGKG+ +Y R K + +A+ + K + ++ V + +
Sbjct: 1118 MENFVLYEELGKGEHSIIYKGRRKGTINFVAIHCIEKCK------RPEVTNTVRMTHDIS 957
Query: 190 HPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHS 249
HPN+++ + ++ + ++L++E G++ L + E + L L Y HS
Sbjct: 956 HPNVVQFHEWYETSNHLWLVVELCTGGSLADILAQDHHLPETSIRDFGIHLVTGLHYIHS 777
Query: 250 KRVIHRDIKPENLLLGSAGELKIADFG----------------------WSVHAPSS--R 285
++ D++P +LL ++G LK ADFG W++ + +
Sbjct: 776 LGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQWNIQSAEEMMK 597
Query: 286 RTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVE 345
+ G+ Y+ PE+ +G DLW+LG + YE G PPF TY T ++ E
Sbjct: 596 QVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSGHPPFLGETYDITKDKVLNKE 417
Query: 346 FTFPDFVTEGAR----------DLISRLLKHNPSQRPMLREVLEH 380
F P +G+R +L+ LL+ + ++R +++H
Sbjct: 416 FPLPK--VKGSRLSAKPSPEFLNLLESLLQKDSTRRLSWASLVKH 288
>06405
Length = 1965
Score = 97.4 bits (241), Expect = 9e-21, Method: Compositional matrix adjust.
Identities = 68/260 (26%), Positives = 118/260 (45%), Gaps = 9/260 (3%)
Frame = +1
Query: 127 QWALEDFEIGRP--LGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEI 184
+W +E EI LG G++G+VY A K+ I+A+K L E + E I
Sbjct: 241 RWEIERTEIAMKHRLGGGQYGDVYEAMWKRYNKIVAVKTL----KEDTMALNDFLEEAAI 408
Query: 185 QSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTA-TYI-TELAN 242
++HPN+++L G Y++ E+ P G + L+ ++ + TA Y+ T++A+
Sbjct: 409 MKEMKHPNLVQLLGVCTREPPFYIVTEFMPHGNLLDYLRSSTREENGPTALMYMATQIAS 588
Query: 243 ALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGT---LDYLPPE 299
++Y +K IHRD+ N L+ + +K+ADFG + T G + + PE
Sbjct: 589 GMAYLETKNFIHRDLAARNCLVADSNMVKVADFGLARLMKDDTYTAHIGAKFPIKWTAPE 768
Query: 300 MIEGRMHDEKVDLWSLGVLCYEFLV-GKPPFEANTYQETYKRISR-VEFTFPDFVTEGAR 357
+ + D+W+ GVL +E G P+ E Y + R P
Sbjct: 769 GLAFNRFSTRSDIWAFGVLLWELATYGMSPYPGVELTEVYHLLERGYRMERPPGTPADVY 948
Query: 358 DLISRLLKHNPSQRPMLREV 377
L+ + + +P RP +E+
Sbjct: 949 ILMLKCWQWDPKDRPTFKEI 1008
>09007
Length = 1440
Score = 94.4 bits (233), Expect = 8e-20, Method: Compositional matrix adjust.
Identities = 71/264 (26%), Positives = 122/264 (46%), Gaps = 20/264 (7%)
Frame = -1
Query: 135 IGRPLGKGKFGNVYLA---REKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHP 191
+ + LG+G FG V A E K +A+K L K ++ K G E +E I L H
Sbjct: 867 LSKSLGQGHFGTVRQAIWTAESGEKVQVAVKCLSKDKIHKDGQE--FLKETAIMQMLDHE 694
Query: 192 NILRLYGYFHD-ATRVYLILEYAPLGTVYRELQKLS---KFDEQRTATYITELANALSYC 247
NI+R+YG D + L+ E AP+ ++ ++++S F R + ++ + +SY
Sbjct: 693 NIVRVYGVVMDNGADIMLVTELAPMRSLLECVKEVSARVDFSVPRLCDFSQQVCDGMSYL 514
Query: 248 HSKRVIHRDIKPENLLLGSAGELKIADFGWSV-------HAPSSRRTTLCGTLDYLPPEM 300
SKR++HRD+ N+LL S ++KI+D G S + S + L + + PE
Sbjct: 513 ESKRLVHRDLAARNILLFSKSKVKISDVGVSGALGAGKEYYQSQQTIHLQNAVAWCAPES 334
Query: 301 IEGRMHDEKVDLWSLGVLCYEFLV-GKPPFEANTYQETYKRIS-----RVEFTFPDFVTE 354
D+W+ GVL +EF G P+ Q+ + + R+E PD +
Sbjct: 333 FRNLCFSSASDVWAFGVLLWEFFTHGFQPWAGLNGQQIMEAVDAPQSQRLE--QPDLCPK 160
Query: 355 GARDLISRLLKHNPSQRPMLREVL 378
++ + + P +RP ++
Sbjct: 159 EYYAVMLKCWEQEPQRRPTFSQLF 88
>13592
Length = 980
Score = 93.2 bits (230), Expect = 2e-19, Method: Compositional matrix adjust.
Identities = 68/270 (25%), Positives = 128/270 (47%), Gaps = 14/270 (5%)
Frame = +2
Query: 139 LGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYG 198
+G+G+FG VY A + ++A+K + E +++ + E++I ++H N++R YG
Sbjct: 8 IGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETRALKN-VAEELKILEGIKHKNLVRYYG 184
Query: 199 YFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIK 258
+ + +E GT+ ++ E + + +L + ++ H ++HRDIK
Sbjct: 185 IEVHREELLIFMELCSEGTLESLVELTGGLPEALSRRFTAQLLSGVAELHKHGIVHRDIK 364
Query: 259 PENL-LLGSAGELKIADFGWSVHAPSSRRTTL-------CGTLDYLPPEMI---EGRMHD 307
N+ L+ + LK+ DFG +V + TT+ GT Y+ PE+ H
Sbjct: 365 TANIFLVDGSNSLKLGDFGSAVKIQA--HTTVPGELQGYVGTQAYMAPEVFTKTNSDGHG 538
Query: 308 EKVDLWSLGVLCYEFLVGKPP---FEANTYQETYKRISRVEFTFPDFVTEGARDLISRLL 364
D+WS+G + E GK P F++N +Q +K + P+ +++ D I L
Sbjct: 539 RLADIWSVGCVVVEMASGKRPWAQFDSN-FQIMFKVGMGEKPQAPESLSQEGHDFIDHCL 715
Query: 365 KHNPSQRPMLREVLEHPWITANSSKPSNCQ 394
+H+P QR E+LE + + + N +
Sbjct: 716 QHDPKQRLSAIELLEQNFCKSGRDEECNSE 805
>13212
Length = 1067
Score = 92.4 bits (228), Expect = 3e-19, Method: Compositional matrix adjust.
Identities = 60/188 (31%), Positives = 96/188 (51%), Gaps = 10/188 (5%)
Frame = -1
Query: 206 VYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLG 265
V+ +L + L ++ +L+K E + E+ AL + H VIHRDIK N+LL
Sbjct: 1049 VFRVLWWGALDSIMVDLEK--PMTEAQICYVCHEMCMALDFLHRHHVIHRDIKAGNVLLT 876
Query: 266 SAGELKIADFGWSVHAPSS--RRTTLCGTLDYLPPEMI-----EGRMHDEKVDLWSLGVL 318
GE+K+ADFG S + +R T GT ++ PE++ + +D K D+WSLGV
Sbjct: 875 IDGEVKLADFGVSAKNTQTQQKRDTFIGTPYWMAPEVVLCETLKDTPYDFKADIWSLGVT 696
Query: 319 CYEFLVGKPPFEANTYQETYKRISRVE---FTFPDFVTEGARDLISRLLKHNPSQRPMLR 375
EF +PP + +I + + P T+ +D I++ L +P+ RP
Sbjct: 695 LIEFAQIEPPNKEMHPMRVLIKIHKSDPPTLEKPKKWTKLFKDFIAKCLVKDPNLRPTAA 516
Query: 376 EVLEHPWI 383
E+LEHP++
Sbjct: 515 ELLEHPFM 492
>01392
Length = 1806
Score = 90.5 bits (223), Expect = 1e-18, Method: Compositional matrix adjust.
Identities = 57/189 (30%), Positives = 90/189 (47%), Gaps = 34/189 (17%)
Frame = -1
Query: 230 EQRTATYITELANALSYCHSKRVIHRDIKPENLL---LGSAGELKIADF----GWSVHAP 282
E+ + + +A AL + HSK + HRD+KPEN+L L +KI DF G S
Sbjct: 1794 EREASLVVRHIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGISCDGD 1615
Query: 283 SSRRTTL---CGTLDYLPPEMIEGRM-----HDEKVDLWSLGVLCYEFLVGKPPFEANTY 334
++ L G+ +Y+ PE+++ + +D++ DLWSLG++ Y L G PPF
Sbjct: 1614 GTKTPELLTPVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILYIMLCGYPPFYGQCG 1435
Query: 335 QET---------------YKRISRVEFTFPD----FVTEGARDLISRLLKHNPSQRPMLR 375
++ + I + FP ++ A+DLI LL P +R
Sbjct: 1434 EDCGWNRGEACHDCQDMLFNSIQDGHYKFPSQEWTSISSSAKDLIRHLLVREPRKRYSAA 1255
Query: 376 EVLEHPWIT 384
+VL+HPWI
Sbjct: 1254 DVLKHPWIC 1228
>01756
Length = 1858
Score = 87.0 bits (214), Expect = 1e-17, Method: Compositional matrix adjust.
Identities = 66/222 (29%), Positives = 106/222 (47%), Gaps = 16/222 (7%)
Frame = -3
Query: 139 LGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYG 198
+G+G FG V+ AR K++K ++A+K + EK G RE++I L H N++ L
Sbjct: 1718 IGQGTFGEVFKARCKKTKQVVAMKKVLMDN-EKEGFPITALREIKILQLLNHENVVDLIE 1542
Query: 199 YFH----DATR----VYLILEYA--PLGTVYRELQKLSKFDEQRTATYITELANALSYCH 248
A R YL+ E+ L + + + E + + +L N L Y H
Sbjct: 1541 ICSTKATSANRYKSMFYLVFEFCEHDLAGLLSNMSVVFNLPEIKEV--MKQLMNGLYYIH 1368
Query: 249 SKRVIHRDIKPENLLLGSAGELKIADFG----WSVHAPS-SRRTTLCGTLDYLPPEMIEG 303
+++HRD+K N+L+ G LK+ADFG +SV+ +R T TL Y PPE++ G
Sbjct: 1367 RNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRPPELLLG 1188
Query: 304 -RMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRV 344
R + +D W G + E P + T Q I+++
Sbjct: 1187 DRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQNQLTLITQL 1062
>13066
Length = 551
Score = 87.0 bits (214), Expect = 1e-17, Method: Compositional matrix adjust.
Identities = 50/164 (30%), Positives = 87/164 (53%), Gaps = 6/164 (3%)
Frame = +3
Query: 159 LALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTV 218
LA K++ K + VE RE+++ + L HP I++++ + ++ + +A G +
Sbjct: 60 LACKIIDKEKAPVDFVEKFFPRELDLLTKLDHPYIIQIHSILQRXPKNFIFMRFAERGDL 239
Query: 219 YRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS 278
+Q++ E++ + ++ AL+Y HS V HRD+K EN+LL S +K+ADFG++
Sbjct: 240 LTYIQEVGFVKEKQAKIWFYQMTTALNYLHSYDVAHRDLKCENILLSSHFNVKLADFGFA 419
Query: 279 VHAPSS-----RRTTLCGTLDYLPPEMIEGRMHDEKV-DLWSLG 316
+ T CG+ Y PE++ G + KV D WSLG
Sbjct: 420 CACITESGEKYMSRTYCGSAAYAAPEIVYGAPYAPKVADAWSLG 551
>11780
Length = 1713
Score = 80.1 bits (196), Expect(2) = 2e-17, Method: Compositional matrix adjust.
Identities = 57/202 (28%), Positives = 100/202 (49%), Gaps = 7/202 (3%)
Frame = +3
Query: 121 EESKKRQW--ALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQL 178
+E K W A +D EIG +GKG FG+VY + V K +K E
Sbjct: 561 QEFKSGGWVIAXQDLEIGEAIGKGDFGDVYKGMYRGQP------VAIKQLKDKDRGEQSF 722
Query: 179 RREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSK--FDEQRTATY 236
+E + + LRH N++RL G T ++L+ E+ G + L+ + ++ +
Sbjct: 723 LQEASVMTSLRHDNLVRLIGVVLGET-IFLVTEFMGKGNLVEYLRSRGRSVITKKDQINF 899
Query: 237 ITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYL 296
T+ A+ Y SKR++HRD+ N+L+ G+ K++DFG + S +T++ + +
Sbjct: 900 ATDTCAAMEYLESKRLVHRDLAARNVLVHDDGKAKVSDFGLAKFGDFS-QTSVKFPIKWT 1076
Query: 297 PPEMI-EGRMHDE--KVDLWSL 315
PE + E ++H + V+LW +
Sbjct: 1077APEALRENKIH*QVRHVELWHI 1142
Score = 26.6 bits (57), Expect(2) = 2e-17, Method: Compositional matrix adjust.
Identities = 16/72 (22%), Positives = 33/72 (45%), Gaps = 2/72 (2%)
Frame = +1
Query: 309 KVDLWSLGVLCYE-FLVGKPPFEANTYQETYKRISR-VEFTFPDFVTEGARDLISRLLKH 366
K D+WS G+L +E + G+ P+ + + R P+ ++ + +
Sbjct: 1114 KSDMWSFGILLWEIYSFGRVPYPRIPLTDVVMHVERGYRMEAPEGCPPEIYSIMKQAWEL 1293
Query: 367 NPSQRPMLREVL 378
+P++RP + VL
Sbjct: 1294 DPNERPTFKSVL 1329
>04591
Length = 1117
Score = 86.3 bits (212), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 60/184 (32%), Positives = 88/184 (47%), Gaps = 12/184 (6%)
Frame = -2
Query: 171 KAGVEHQLRREVEIQSHLRHPNILRLYGYFHD--------ATRVYLILEYAP--LGTVYR 220
K G RE++I L H N+++L H + YLI EY L +
Sbjct: 1101 KEGFPITALREIKILQQLEHENVVQLQEICHTQAGPYNRYKSTFYLIFEYCDYDLAGLLN 922
Query: 221 ELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSV- 279
L+ KF +++L N L Y H+K+++HRDIK N+LL G LK+ADFG S
Sbjct: 921 NLR--VKFSLADKKNLMSQLLNGLFYIHTKQILHRDIKAANILLTRDGVLKLADFGLSRP 748
Query: 280 HAPSSRRTTLCGTLDYLPPEMIEG-RMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETY 338
S R T TL Y PPE++ G R + ++D+W +G + E KP + + Q
Sbjct: 747 WVKSKRLTNRVVTLWYRPPELLLGEREYGPEIDMWGVGCIMAEMWSRKPLMQGRSEQHQL 568
Query: 339 KRIS 342
I+
Sbjct: 567 SLIT 556
>01718
Length = 959
Score = 85.9 bits (211), Expect = 3e-17, Method: Compositional matrix adjust.
Identities = 62/209 (29%), Positives = 99/209 (47%), Gaps = 11/209 (5%)
Frame = +3
Query: 130 LEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLR 189
L+DF I +G G F V+ + + ++ALK+ H + REV++ + L+
Sbjct: 147 LDDF-ICEKIGAGFFSEVFKVTHRITGQVMALKMN-----TMTSNRHNMLREVQLLNRLQ 308
Query: 190 HPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTAT----YITELANALS 245
H NILR G +++ + EY P G + Q L K DE+ T LA L
Sbjct: 309 HANILRFMGVCVHEGQLHALTEYIPSGNLE---QLLEKKDEELPWTQRIQLTLGLARGLD 479
Query: 246 YCHSKRVIHRDIKPENLLL----GSAGELKIADFGWSVHAP---SSRRTTLCGTLDYLPP 298
Y HS R IHRD+ +N+L+ IADFG + P + G+ ++ P
Sbjct: 480 YLHSTRFIHRDLTSKNILIRREDNHGYHAVIADFGLATKIPDPLDKEKLPTVGSPYWMAP 659
Query: 299 EMIEGRMHDEKVDLWSLGVLCYEFLVGKP 327
E++ G ++E+ DL+S+G++ E P
Sbjct: 660 EVLNGHFYNERADLFSVGIIMCEITARIP 746
>17975
Length = 449
Score = 85.1 bits (209), Expect = 4e-17, Method: Compositional matrix adjust.
Identities = 51/137 (37%), Positives = 80/137 (58%), Gaps = 2/137 (1%)
Frame = +3
Query: 144 FGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDA 203
F V LAR + +A+KV+ K +L++ H L +EV ++HPN++RLY
Sbjct: 6 FAVVKLARHVFTGEKVAVKVIDKTKLDEVSRSH-LFQEVRCMKLVQHPNVVRLYEVIDTQ 182
Query: 204 TRVYLILEYAPLGTVYRELQKLSKFDEQRTAT-YITELANALSYCHSKRVIHRDIKPENL 262
T++YLILE G +Y + + S E++ A Y ++ A+SYCH V+HRD+KPEN+
Sbjct: 183 TKLYLILELGDGGDMYDYIMRHSGGLEEKLAKRYFRQIVEAISYCHKLHVVHRDLKPENV 362
Query: 263 LLGSA-GELKIADFGWS 278
+ G +K+ DFG+S
Sbjct: 363 VFFEKPGLVKLTDFGFS 413
>31885
Length = 529
Score = 84.3 bits (207), Expect = 7e-17, Method: Compositional matrix adjust.
Identities = 48/158 (30%), Positives = 81/158 (51%), Gaps = 6/158 (3%)
Frame = -2
Query: 182 VEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELA 241
V++ + L HP ++ L+ F D ++++++ G + +Q+ F E Y+ +LA
Sbjct: 519 VDMLTRLDHPFLVNLWYAFQDEEDLFMVVDLFLGGDLRYHMQQEVSFREDCVKFYLCQLA 340
Query: 242 NALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSR-RTTLCGTLDYLPPEM 300
L Y S++++HRDIKP+N+LL G + DF + T+ GT Y+ PE+
Sbjct: 339 LVLDYLRSQKIVHRDIKPDNILLDEQGHCHVTDFNIATQLEDDELATSTSGTRPYMAPEV 160
Query: 301 I-----EGRMHDEKVDLWSLGVLCYEFLVGKPPFEANT 333
E R + VD WSLGV +E L + PF ++
Sbjct: 159 YGVAINERRGYGFPVDWWSLGVSLFELLKKRRPFSVHS 46
>27546
Length = 426
Score = 82.8 bits (203), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 42/120 (35%), Positives = 70/120 (58%)
Frame = -1
Query: 159 LALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTV 218
LA K++ KA+ V+ RE+EI + L HPNI++++ ++++ + YA G +
Sbjct: 396 LACKIIDKAKAPIDFVKKFFPRELEILTRLDHPNIIQIHSILQRGPKIFIFMRYAEKGDM 217
Query: 219 YRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS 278
++K DE +T + ++A AL Y HS + HRD+K EN+LL +KIADFG++
Sbjct: 216 LSHIKKTGPIDEAQTKVWFFQMAKALQYLHSHDIAHRDLKCENILLSKRLNVKIADFGFA 37
>00486
Length = 797
Score = 82.0 bits (201), Expect = 3e-16, Method: Compositional matrix adjust.
Identities = 35/84 (41%), Positives = 53/84 (63%)
Frame = -2
Query: 288 TLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFT 347
T CGT++Y+ PE++ H + VD WSLG L Y+ L G PPF A ++T +I + +
Sbjct: 781 TFCGTIEYMAPEILTRTGHGKAVDWWSLGALMYDMLTGSPPFTAENRKKTIDKILKGKLN 602
Query: 348 FPDFVTEGARDLISRLLKHNPSQR 371
P ++T AR LI +LL+ NP++R
Sbjct: 601 LPPYLTNEARGLIKKLLRKNPAER 530
>21079
Length = 878
Score = 81.6 bits (200), Expect = 6e-16, Method: Compositional matrix adjust.
Identities = 42/148 (28%), Positives = 79/148 (53%), Gaps = 4/148 (2%)
Frame = +1
Query: 190 HPNILRLYGYFHDATRVYLILEYAPLGTVY-RELQKLSKFDEQRTATYITELANALSYCH 248
HP +L L+ F + L++E+ G ++ R ++ E+ ++ ++ + + Y H
Sbjct: 1 HPKLLMLWDAFEAPRTMVLVMEFVGAGELFERVIRDDFVLTERDCVHFVRQICSGVGYMH 180
Query: 249 SKRVIHRDIKPENLLLGS--AGELKIADFGWS-VHAPSSRRTTLCGTLDYLPPEMIEGRM 305
++ ++H D+KPEN+L S + ++KI DFG + + P L GT +++ PE++
Sbjct: 181 TQSILHLDLKPENVLCVSDNSNQIKIIDFGLARFYKPGDSLQVLFGTPEFIAPEVVNYDE 360
Query: 306 HDEKVDLWSLGVLCYEFLVGKPPFEANT 333
+ D+WS+GV+CY L G P T
Sbjct: 361 INFTTDMWSIGVICYILLSGLSPSRVTT 444
>00392
Length = 668
Score = 80.5 bits (197), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 48/175 (27%), Positives = 91/175 (52%), Gaps = 9/175 (5%)
Frame = +3
Query: 177 QLRREVEIQSHLRHPNILRLYGYFHDATR-----VYLILEYAPLGTVYRELQKLSKFDEQ 231
+ + E E+ L+HPNI+R + Y+ + + L+ E GT+ L++ K + +
Sbjct: 69 RFKEEAEMLKELQHPNIVRFFDYWEEHNHRNRKVIILVTELMTSGTLKTYLKRFKKPNVK 248
Query: 232 RTATYITELANALSYCHSKR--VIHRDIKPENLLL-GSAGELKIADFGWSVHAPSSRRTT 288
+ ++ L + H++ VIHRD+K +N+ + G G +KI D G + S +
Sbjct: 249 ILKNWCRQVLKGLYFLHTRTPPVIHRDLKCDNIFITGPTGSVKIGDLGLATLKNQSFAKS 428
Query: 289 LCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPF-EANTYQETYKRIS 342
+ GT +++ PEM E +DE VD+++ G+ E + P+ E + + YKR++
Sbjct: 429 VIGTPEFMAPEMYEEH-YDEAVDVYAFGMCMLEMASSEYPYSECSNAAQIYKRVT 590
>01966
Length = 1735
Score = 79.0 bits (193), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 42/135 (31%), Positives = 70/135 (51%), Gaps = 4/135 (2%)
Frame = -1
Query: 173 GVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEY--APLGTVYRELQKLSKFDE 230
GV RE+ + LRH NI+ L + R++L+ E+ L + + D
Sbjct: 1588 GVPSSAIREIAMLRELRHTNIVCLEDVIMEDERLFLVFEFLSMDLKMYIDKFPEGVVLDR 1409
Query: 231 QRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGW--SVHAPSSRRTT 288
+ +Y+ ++ +++CH +R++HRD+KP+NLL+ G +KIADFG + P T
Sbjct: 1408 RLVKSYVFQIVTGINFCHQRRIVHRDLKPQNLLINHTGAIKIADFGMARTFALPVRAYTH 1229
Query: 289 LCGTLDYLPPEMIEG 303
TL Y PE++ G
Sbjct: 1228 EVVTLWYRAPEILMG 1184
>19761
Length = 473
Score = 76.3 bits (186), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 40/142 (28%), Positives = 77/142 (54%), Gaps = 4/142 (2%)
Frame = -3
Query: 230 EQRTATYITELANALSYCHSKR--VIHRDIKPENLLLGSAGELKIADFGWS--VHAPSSR 285
E+ ++ + A+AL+Y H+ ++HRD+KP+N+ + G++++ D G + + P+
Sbjct: 426 ERLIVCWLMQTASALNYMHTHTPVILHRDLKPQNIYVTEKGDVRLGDLGLARKLTGPADF 247
Query: 286 RTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVE 345
T+ GT+ YL PE++ + ++ K D+WSLG + Y+ K E + + +
Sbjct: 246 ATSQVGTIMYLSPEILSQQPYNSKSDIWSLGCVFYDITGKKGSDEMGVMFLLVQVMGGRK 67
Query: 346 FTFPDFVTEGARDLISRLLKHN 367
PD ++ RD ISR+L +
Sbjct: 66 LPLPDHYSQEFRDTISRMLTKD 1
>19094
Length = 898
Score = 70.1 bits (170), Expect(2) = 6e-14, Method: Compositional matrix adjust.
Identities = 39/103 (37%), Positives = 57/103 (55%), Gaps = 2/103 (1%)
Frame = +1
Query: 230 EQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS--VHAPSSRRT 287
E+ AT + L Y HS+R IHRDIK N+LL + G K+ADFG + + ++R
Sbjct: 55 EREIATILYYTLKGL*YLHSRRKIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRN 234
Query: 288 TLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFE 330
T+ GT ++ PE+I+ +D D+WSLG+ E G E
Sbjct: 235 TVIGTPYWMAPEVIQEIGYDCVADIWSLGITALEMAEGNLHME 363
Score = 24.6 bits (52), Expect(2) = 6e-14, Method: Compositional matrix adjust.
Identities = 12/38 (31%), Positives = 19/38 (50%)
Frame = +3
Query: 346 FTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWI 383
F PD + D +S+ L NP R ++L+H +I
Sbjct: 417 FRQPDKWSTEFIDFVSKCLVKNPENRATAVDLLQHDFI 530
>26560
Length = 398
Score = 74.7 bits (182), Expect = 7e-14, Method: Composition-based stats.
Identities = 40/131 (30%), Positives = 67/131 (51%), Gaps = 1/131 (0%)
Frame = -1
Query: 218 VYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGW 277
++ L + F E+ Y E+ L + HS+ V++RD+KP N+LL G ++I+D G
Sbjct: 395 LHYHLSQHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGL 216
Query: 278 SVHAPSSRRTTLCGTLDYLPPE-MIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQE 336
+ R GT Y+ PE +++G+ +D D +S G + Y+ L G PF + +
Sbjct: 215 ACDFSKKRPHASVGTHGYMAPEVLMKGQSYDSSADWFSFGCMLYKLLKGHSPFR--QHNQ 42
Query: 337 TYKRISRVEFT 347
RI R+ T
Sbjct: 41 GQARIDRMTMT 9
>29581
Length = 1278
Score = 72.0 bits (175), Expect = 4e-13, Method: Compositional matrix adjust.
Identities = 63/235 (26%), Positives = 101/235 (42%), Gaps = 38/235 (16%)
Frame = -2
Query: 187 HLRHPNILRL----YGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELAN 242
+LRH NI++L G D+ ++L++EY + F E + + +L
Sbjct: 1187 NLRHQNIVQLQEVVVGKSLDS--LFLVMEYCEQDLASLLDNMPAPFSESQVKCIVLQLLK 1014
Query: 243 ALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVH--APSSRRTTLCGTLDYLPPEM 300
L Y H +IHRD+K NLL+ G +KIADFG + + P T TL Y PE+
Sbjct: 1013 GLRYLHEAFIIHRDLKVSNLLMTDKGCVKIADFGLARNYGKPQKPMTPKVVTLWYRAPEL 834
Query: 301 IEG-RMHDEKVDLWSLGVLCYEFLVGKPPFEANT-------------------------- 333
+ G + H +D+WS G + E L KP +
Sbjct: 833 LFGSKTHSTAIDMWSAGCILGELLGHKPLMPGRSDLQQIELIMELLGTPNDTIWPGFSQL 654
Query: 334 ---YQETYKR--ISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWI 383
Q T K+ + + TFP +++E L++ L ++P +R + LEH +
Sbjct: 653 PAFEQFTLKKQPYNNLRHTFP-WLSESGIRLLNGLFMYHPQKRATAEDCLEHSYF 492
>20152
Length = 445
Score = 68.9 bits (167), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 32/96 (33%), Positives = 50/96 (52%), Gaps = 1/96 (1%)
Frame = +1
Query: 298 PEMIEGRMHDE-KVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGA 356
PE++ G +D VD+WSLGV+ Y +VG+ PF+ ET I + P ++
Sbjct: 1 PEILLGDSYDAPAVDVWSLGVILYMLVVGEAPFQEANDSETLTMIMDCRYQIPPHISHKC 180
Query: 357 RDLISRLLKHNPSQRPMLREVLEHPWITANSSKPSN 392
+DLI ++L+ P R L +L HPW+ P+
Sbjct: 181 QDLIEKMLQREPVDRASLPHILAHPWLNDGDLTPTT 288
>27405
Length = 532
Score = 67.8 bits (164), Expect = 7e-12, Method: Compositional matrix adjust.
Identities = 47/175 (26%), Positives = 84/175 (48%), Gaps = 5/175 (2%)
Frame = -3
Query: 144 FGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLR----HPNILRLYGY 199
FG VY R+ + + A+K L K +++ G E E + S + P I+ +
Sbjct: 527 FGEVYGCRKADTGKMYAMKCLDKKRIKMKGGETLALNERIMLSLVSTGEGSPFIVCMTYA 348
Query: 200 FHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKP 259
F ++ IL+ G ++ L + F E+ Y E+ L + HS+ V++RD+KP
Sbjct: 347 FQTPEKLCFILDLMNGGDLHYHLSQHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKP 168
Query: 260 ENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPE-MIEGRMHDEKVDLW 313
N+LL G ++I+D G + + GT Y+ PE +++G+ +D D +
Sbjct: 167 ANILLDENGHVRISDLGLACDFSKKKPHASVGTHGYMAPEVLMKGQAYDSSADWF 3
>26711
Length = 405
Score = 65.9 bits (159), Expect = 3e-11, Method: Composition-based stats.
Identities = 39/132 (29%), Positives = 72/132 (54%), Gaps = 8/132 (6%)
Frame = -2
Query: 237 ITELANALSYCHSKRVIHRDIKPENLLLG--SAGELKIADFGWSVHAPSSRRTTLC-GTL 293
+ ++ + L + H++ V+H D+KP NLLL +++ DFG + + T L GT
Sbjct: 398 VKQVLDILQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARKLYPPQETFLNHGTP 219
Query: 294 DYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTF---PD 350
+ PE ++ + D+W +GVL Y L G+ PF+A++ E+ K+ +++F P
Sbjct: 218 GFTSPEALDVKPISTASDVWGVGVLAYILLSGQSPFQADSATESLKKTQTCDWSFDVCPS 39
Query: 351 F--VTEGARDLI 360
F +++ A+D I
Sbjct: 38 FSNMSQDAKDFI 3
>19301
Length = 712
Score = 65.1 bits (157), Expect = 5e-11, Method: Compositional matrix adjust.
Identities = 33/101 (32%), Positives = 56/101 (55%), Gaps = 2/101 (1%)
Frame = +2
Query: 180 REVEIQS--HLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYI 237
+E +I++ L HPNI+ G A +I+EY P G +Y L+ + +
Sbjct: 410 KETDIRNLRKLNHPNIISFKGVCTQAPCYCIIMEYCPYGQLYEVLRDGKEIPPALVLDWS 589
Query: 238 TELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS 278
++A+ ++Y HS ++IHRD+K N+L+ +KI+DFG S
Sbjct: 590 KQIASGMNYLHSHKIIHRDLKSPNVLVAKNDVVKISDFGTS 712
>38560
Length = 479
Score = 64.7 bits (156), Expect = 6e-11, Method: Compositional matrix adjust.
Identities = 33/111 (29%), Positives = 58/111 (52%), Gaps = 1/111 (0%)
Frame = -3
Query: 287 TTLCGTLDYLPPEMIEGRMH-DEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVE 345
TT CG+ Y PE+I G + + D+WS+GVL Y L G PF+ ++ + +
Sbjct: 411 TTCCGSPAYAAPELISGLEYLGSEADIWSMGVLLYALLCGYLPFDDEKXSHL*QKNQKRK 232
Query: 346 FTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQNK 396
P++++E L+ +L+ +PS R +R +L+H W+ + P +K
Sbjct: 231 DEVPEWLSEDTTKLLEGMLQTDPSHRITIRRLLDHHWLNQGFNVPVEWASK 79
>14477
Length = 493
Score = 63.9 bits (154), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 44/142 (30%), Positives = 73/142 (51%), Gaps = 2/142 (1%)
Frame = -1
Query: 139 LGKGKFGNVY--LAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRL 196
LG G FG+V + R + +A+KVL A L+ + V+ +L +E E+ + H +I+RL
Sbjct: 466 LGAGNFGSVMKGVCRLDDREIPVAIKVLKNADLDPS-VQSELIKEAEVMKKMDHMHIVRL 290
Query: 197 YGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRD 256
G T + L+LE A LG + + L K + +++ + Y + + +HRD
Sbjct: 289 IGLCEGET-MMLVLELAKLGPLNKFLPKNKHLPLWNILELMWQVSQGMEYLEANKFVHRD 113
Query: 257 IKPENLLLGSAGELKIADFGWS 278
+ N+LL KI+DFG S
Sbjct: 112 LAARNILLCDEHFAKISDFGMS 47
>04852
Length = 1462
Score = 63.9 bits (154), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 40/151 (26%), Positives = 75/151 (49%), Gaps = 5/151 (3%)
Frame = +1
Query: 235 TYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTL- 293
+Y ++A + + S++ IHRD+ N+L+ LKIADFG S ++ + G L
Sbjct: 337 SYAFQIARGMEFLASRKCIHRDLAARNVLVTEEHVLKIADFGLSRTGDYYKKRS-GGRLP 513
Query: 294 -DYLPPEMIEGRMHDEKVDLWSLGVLCYE-FLVGKPPFEANTYQETYKRISRVEFTF--P 349
++ PE + + K D+WS GV+ +E F +G P+ + +E Y ++ + P
Sbjct: 514 VKWMAPEALFDMRYTTKSDVWSFGVVLWEIFSLGGMPYASIPNEELYSKLLDDAYRMPRP 693
Query: 350 DFVTEGARDLISRLLKHNPSQRPMLREVLEH 380
+ + ++ R + PS RP +++ H
Sbjct: 694 ELASGNLYAIMERCWLNRPSDRPEFSQLVGH 786
>06358
Length = 1517
Score = 63.5 bits (153), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 65/273 (23%), Positives = 121/273 (44%), Gaps = 40/273 (14%)
Frame = +3
Query: 140 GKGKFGNVYLAREKQSK-----FILALKVLFK-AQLEKAGVEHQLRREVEIQSHLRHPNI 193
G G V+ A +K +K F+ K + + ++ ++ + LR V+ + LRHP I
Sbjct: 33 GPGLLWKVFAASKKSTKEEASVFVFEKKSVDRYSRRDREAIVEVLRVGVQQLTKLRHPKI 212
Query: 194 LRLYGYFHD-------------ATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITEL 240
L + + A+ ++ + + + TV +ELQ +D + + ++
Sbjct: 213 LAVINPLEESRETLAFATEPVFASLANVLGDLSSIXTVPKELQDYQLYDVE-IKHGLLQV 389
Query: 241 ANALSYCHSK-RVIHRDIKPENLLLGSAGELKIADFGWSVHA--PSSR---------RTT 288
AL + H+ +++HR++ PE ++L G K+A + + V + P S R+
Sbjct: 390 TEALGFLHNDAKMMHRNVCPEAIMLTKLGSWKLAGYEFCVRSSDPQSTDPSYPFYEWRSD 569
Query: 289 LCGT----LDYLPPEMIEGRMHDEKVDLWSLGVLCYE-FLVGKPPFEAN----TYQETYK 339
+ LD++ PE + D++SLG+L Y F GKP FE N ++ +
Sbjct: 570 IAPVTQPHLDFMAPEYVLTMQCGTGSDMFSLGLLVYSVFAKGKPLFECNGELSAFKSNAE 749
Query: 340 RISRVEFTFPDFVTEGARDLISRLLKHNPSQRP 372
+ + + V E RD + LL P+ RP
Sbjct: 750 ELRHMRVSLLGVVPEDLRDHVKLLLNIEPAVRP 848
>04138
Length = 800
Score = 63.5 bits (153), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 51/177 (28%), Positives = 72/177 (40%), Gaps = 40/177 (22%)
Frame = +1
Query: 244 LSYCHSKRVIHRDIKPENLLLGSAGELKIADFG----WSVHAPS-SRRTTLCGTLDYLPP 298
L Y H +++HRD+K N+L+ G LK+ADFG +SV+ +R T TL Y PP
Sbjct: 52 LYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRPP 231
Query: 299 EMIEG-RMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGAR 357
E++ G R + +D W G + E P + T Q I+++ + V G
Sbjct: 232 ELLLGDRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQNQLTLITQLCGSITPEVWPGVT 411
Query: 358 ----------------------------------DLISRLLKHNPSQRPMLREVLEH 380
DL RLLK +PSQR E L H
Sbjct: 412 QLSMYHQIKGALAAGRKNIIRDRFARILKDPYGLDLFERLLKMDPSQRISADEALNH 582
>21808
Length = 1011
Score = 63.2 bits (152), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 43/166 (25%), Positives = 73/166 (43%), Gaps = 5/166 (3%)
Frame = +1
Query: 181 EVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYI-TE 239
E +I LRHP +++LY +++I E G++ LQ + + I +
Sbjct: 82 EAQIMKKLRHPKLIQLYAVCTQDDPIFIITELMKNGSLLEFLQGKGRVLKLPALIDIGAQ 261
Query: 240 LANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGT---LDYL 296
+A ++Y S+ IHRD+ N+L+ +KIADFG + G + +
Sbjct: 262 IACGMAYLESQNYIHRDLAARNILVSDNNTVKIADFGLARVIKEDEYEARVGARFPIKWT 441
Query: 297 PPEMIEGRMHDEKVDLWSLGVLCYEFLV-GKPPFEANTYQETYKRI 341
PE K D+WS G+L E + G+ P+ T E ++
Sbjct: 442 APEAANYNRFTIKSDVWSFGILLTETVTYGRVPYPGMTNAEVLHQV 579
>00715
Length = 1788
Score = 61.6 bits (148), Expect = 5e-10, Method: Compositional matrix adjust.
Identities = 47/177 (26%), Positives = 76/177 (42%), Gaps = 33/177 (18%)
Frame = +1
Query: 188 LRHPNILRLYGY-----FHDATRVYLILEYAP---LGTVYRELQKLSKFDEQRTATYITE 239
LRH N++ + G F D +L +EY L T+ + Q+ D + +
Sbjct: 97 LRHVNVVSILGATSLHRFEDGA--WLAMEYVGPLNLQTILNDHQQ--DIDSSMRLSLALQ 264
Query: 240 LANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVH------------------- 280
+A L Y HS ++H D+KP N LL +L+IADFG H
Sbjct: 265 MARGLHYLHSINIVHLDLKPANCLLTRDLKLRIADFG-CCHQLTPTGLDMGEREGGMAGN 441
Query: 281 ------APSSRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEA 331
+ + L GTL Y PE+++G + D++SLG+ ++ + P+E
Sbjct: 442 ELELTPVQGAWKNELAGTLAYRAPELLKGLQPSVRSDVYSLGITLWQMCTRQGPYEG 612
>14116
Length = 1017
Score = 61.2 bits (147), Expect = 6e-10, Method: Compositional matrix adjust.
Identities = 56/217 (25%), Positives = 96/217 (44%), Gaps = 24/217 (11%)
Frame = -1
Query: 131 EDFEIGRPLGKGKFGNV---YLAR-EKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQS 186
E +G +GKG FG V +L E++ ++A+K L RE+E+QS
Sbjct: 636 EFLTMGEEIGKGNFGCVKRGFLTLPEQKGDILVAVKTLHNNN----------PREIELQS 487
Query: 187 HLR---------HPNILRLYGY---FHDATRVYL-ILEYAPLGTVYRELQKLSKFDEQRT 233
L+ H N+L L G D V L +++ L T R+ Q +
Sbjct: 486 FLQEALIMKDFHHSNVLTLIGICLNLDDMPLVVLPFMKHGDLLTYIRDDQHQPTIKD--L 313
Query: 234 ATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS-------VHAPSSRR 286
Y ++A + Y + +HRD+ N +L +K+ADFG + ++ +++
Sbjct: 312 IMYGVDIARGMDYLAGLKFVHRDLAARNCMLDEDFHVKVADFGLARDIYEKEYYSSENKK 133
Query: 287 TTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFL 323
L + ++ E +E +D K D+WS GV+ +E L
Sbjct: 132 AKL--PVKWMALESLEKGNYDSKTDVWSYGVVLWELL 28
>28157
Length = 400
Score = 61.2 bits (147), Expect = 8e-10, Method: Compositional matrix adjust.
Identities = 39/104 (37%), Positives = 57/104 (54%), Gaps = 7/104 (6%)
Frame = +3
Query: 180 REVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLS---KFDEQRTATY 236
+E++ S + HPNI+ LYG D V L++EYA G++Y L ++ +
Sbjct: 57 QELKQLSRVSHPNIVCLYGACRDHP-VCLVMEYAEGGSLYNVLHGSGPQPQYTAAHAMNW 233
Query: 237 ITELANALSYCHS---KRVIHRDIKPENLLLGSAG-ELKIADFG 276
+ + A + Y H K +IHRD+KP NLLL G +LKI DFG
Sbjct: 234 LLQCALGVEYLHGMKPKALIHRDLKPPNLLLIQCGTKLKICDFG 365
>12672
Length = 773
Score = 60.8 bits (146), Expect = 9e-10, Method: Compositional matrix adjust.
Identities = 45/161 (27%), Positives = 69/161 (42%), Gaps = 24/161 (14%)
Frame = +3
Query: 241 ANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTT------LCGTLD 294
A+ + Y + +HRDIK N+LL S K+ DF V APS T + GT
Sbjct: 21 ASGIQYLNDNGHVHRDIKTANILLDSEYTAKVGDFATVVSAPSGEGKTVQNASVVIGTAA 200
Query: 295 YLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTY------------------QE 336
YL PE I + K+D +S GV+ E + G A Y +E
Sbjct: 201 YLAPEAIHFDVS-TKLDSYSFGVVLLEVITG---LVAQDYSREERTLSSHIMENVEEPEE 368
Query: 337 TYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREV 377
+ + + T+PD + D+ R L + QRP ++++
Sbjct: 369 IHDFVDQSAGTWPDGAVDKLYDISMRCLNLSKKQRPNVKDI 491
>07940
Length = 1336
Score = 60.8 bits (146), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 36/100 (36%), Positives = 54/100 (54%), Gaps = 5/100 (5%)
Frame = -3
Query: 235 TYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS--VHAPSSRRTTLCGT 292
+Y ++A + Y SK+ IHRD+ N+L+ LKIADFG + + R T G
Sbjct: 335 SYAYQVARGMEYLASKQCIHRDLAARNVLVAEEYVLKIADFGLTRNLQQFDYYRKTTDGR 156
Query: 293 L--DYLPPEMIEGRMHDEKVDLWSLGVLCYE-FLVGKPPF 329
L ++ PE + R + K D+WS GVL +E F +G P+
Sbjct: 155 LPVKWMAPEALFDRKYTSKSDVWSYGVLLWEIFTLGGNPY 36
Score = 34.3 bits (77), Expect = 0.088, Method: Compositional matrix adjust.
Identities = 28/95 (29%), Positives = 49/95 (51%), Gaps = 7/95 (7%)
Frame = -3
Query: 131 EDFEIGRPLGKGKFGNVYLAREKQSKF------ILALKVLFKAQLEKAGVEHQLRREVEI 184
E +G LG+G FG V + E F +A+K+L + ++ ++ L RE+E+
Sbjct: 842 ERLVLGDRLGEGAFGLV-MKGEAMGIFKDNNSVTVAVKMLKEDATDREMMD--LIREMEM 672
Query: 185 QSHL-RHPNILRLYGYFHDATRVYLILEYAPLGTV 218
+ +H NI+ L G +Y+I+E+AP G +
Sbjct: 671 MKVIGKHKNIINLLGCCTQRGALYVIVEFAPHGNL 567
>03508
Length = 1463
Score = 60.8 bits (146), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 31/109 (28%), Positives = 57/109 (52%), Gaps = 3/109 (2%)
Frame = +1
Query: 223 QKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAG-ELKIADFGWS-VH 280
Q F + Y+ EL AL +CHS ++HRD+KP N+++ +L++ D+G + +
Sbjct: 847 QLYQTFTDYDIRFYLYELMKALDFCHSMGIMHRDVKPHNVMIDHENKKLRLIDWGLAEFY 1026
Query: 281 APSSRRTTLCGTLDYLPPE-MIEGRMHDEKVDLWSLGVLCYEFLVGKPP 328
P + + PE +++ +M+D +D+WSLG + + K P
Sbjct: 1027HPGMEYNVRVASRYFKGPELLLDYQMYDYSLDMWSLGCMFASMIFRKEP 1173
>26009
Length = 886
Score = 40.8 bits (94), Expect(2) = 3e-09, Method: Compositional matrix adjust.
Identities = 17/49 (34%), Positives = 30/49 (61%)
Frame = +3
Query: 216 GTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLL 264
GT ++ + + + +L +AL + HSK+++HRDIKPEN+L+
Sbjct: 666 GTCLTPSRRNKACGSREAKSVMKQLVSALDFMHSKQLVHRDIKPENVLI 812
Score = 38.1 bits (87), Expect(2) = 3e-09, Method: Compositional matrix adjust.
Identities = 26/91 (28%), Positives = 47/91 (51%), Gaps = 2/91 (2%)
Frame = +2
Query: 131 EDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLR- 189
E +++ + LG+G +G V LAR + + +ALK+L K+ + + +RE ++ L
Sbjct: 416 EHYDVCKELGRGTYGKVVLARCRHTGTQVALKLLPKSCTKL----REFQREFQLSYFLSP 583
Query: 190 HPNILRLYGY-FHDATRVYLILEYAPLGTVY 219
H NI+ Y F + E+A LG ++
Sbjct: 584 HANIIDTYNVAFQTRSSYVFAQEHAVLGDLF 676
>12786
Length = 460
Score = 58.9 bits (141), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 37/127 (29%), Positives = 54/127 (42%), Gaps = 24/127 (18%)
Frame = -3
Query: 228 FDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRT 287
D Y E+ A+ H++ VIH D+KP N +L AG LK+ DFG + + +
Sbjct: 419 LDRMMIKFYWREMLRAVKALHNEGVIHSDLKPANFML-VAGNLKLIDFGIANTLQQDKTS 243
Query: 288 TL----CGTLDYLPPEMIEGRMHDE--------------------KVDLWSLGVLCYEFL 323
L GT Y+ PE I D + D+WSLG + Y +
Sbjct: 242 VLKDSRVGTPSYMSPEAIMAACDDSADDSMEEDGHRTKPKYKVGVRSDVWSLGCILYNMV 63
Query: 324 VGKPPFE 330
G+ PF+
Sbjct: 62 YGRTPFQ 42
>18663
Length = 600
Score = 57.8 bits (138), Expect = 7e-09, Method: Compositional matrix adjust.
Identities = 32/112 (28%), Positives = 52/112 (46%), Gaps = 15/112 (13%)
Frame = +2
Query: 287 TTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEA---------NTYQET 337
+T CGT +Y+ PE++ G + VD W+LGVL YE L G+ PF+ NT
Sbjct: 2 STFCGTPNYIAPEILRGEDYGFSVDWWALGVLLYEMLAGRSPFDIAGASENPDQNTEDYL 181
Query: 338 YKRISRVEFTFPDFVTEGARDLISRLLKHNPSQR------PMLREVLEHPWI 383
++ I P ++ A ++ L NP+ R +++ HP+
Sbjct: 182 FQVILEKTIRIPRSLSVKAASVLKGFLNKNPADRLGCHRESAFMDIVNHPFF 337
>28638
Length = 1458
Score = 55.8 bits (133), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 41/132 (31%), Positives = 60/132 (45%), Gaps = 5/132 (3%)
Frame = -1
Query: 203 ATRVYLILEYAP-LGTVYRELQKLSKFDEQRTATYITELANALSYCHS--KRVIHRDIKP 259
AT L +P + T Q L T + +L AL + + +IH D+KP
Sbjct: 924 ATTCVWCLSCSPTISTTCYATQTLEGVSLNLTRKFAQQLCTALLFLATPEMNIIHCDLKP 745
Query: 260 ENLLLGSA--GELKIADFGWSVHAPSSRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGV 317
EN+LL + +KI DFG S R + Y PE++ G +D +D+WSLG
Sbjct: 744 ENILLCNPKRSAIKIVDFGSSCQL-GQRIYQYIQSRFYRSPEVLLGVPYDLAIDMWSLGC 568
Query: 318 LCYEFLVGKPPF 329
+ E G+PP
Sbjct: 567 ILVEMHTGEPPL 532
>02638
Length = 1490
Score = 53.1 bits (126), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 27/104 (25%), Positives = 52/104 (50%), Gaps = 5/104 (4%)
Frame = +1
Query: 289 LCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFT- 347
L GT+ ++ PE++ G + D+WS+G + E +PP+ ++ I ++ +
Sbjct: 16 LLGTIAFMAPEVLRGESYGRACDVWSVGCVMIEMCTCRPPWNSHDISNHLALIFKIASSV 195
Query: 348 ----FPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANS 387
P+ ++ RDL+ R L+ + RP +++L HP T S
Sbjct: 196 DPPPIPENMSPPVRDLMLRCLEQDSDFRPSAKDLLMHPLFTKYS 327
>11185
Length = 473
Score = 52.4 bits (124), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 30/110 (27%), Positives = 48/110 (43%), Gaps = 24/110 (21%)
Frame = +1
Query: 240 LANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFG----------------------W 277
L L Y HS ++ D++P +LL ++G LK ADFG W
Sbjct: 28 LVTGLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQW 207
Query: 278 SVHAPSS--RRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVG 325
++ + ++ G+ Y+ PE+ +G DLW+LG + YE G
Sbjct: 208 NIQSAEEMMKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSG 357
>25019
Length = 730
Score = 52.4 bits (124), Expect = 4e-07, Method: Compositional matrix adjust.
Identities = 25/59 (42%), Positives = 35/59 (59%), Gaps = 2/59 (3%)
Frame = +3
Query: 260 ENLLLGSAGELKIADFGWSVHAPSSRRTT--LCGTLDYLPPEMIEGRMHDEKVDLWSLG 316
EN+LL G +K+ DFG A + R T CGT++Y+ PE++ H + VD WSLG
Sbjct: 261 ENVLLDKDGHVKLTDFGLCKEAITGTRVTHTFCGTIEYMAPEILTRTGHGKAVDWWSLG 437
>29590
Length = 320
Score = 38.9 bits (89), Expect(2) = 1e-06, Method: Composition-based stats.
Identities = 17/41 (41%), Positives = 24/41 (58%)
Frame = +3
Query: 289 LCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPF 329
+ GT DY+ PE+++ + D+WSLGVL Y L PF
Sbjct: 54 IIGTPDYVAPEVLDYEPLSIQTDMWSLGVLSYVMLTACSPF 176
Score = 31.2 bits (69), Expect(2) = 1e-06, Method: Composition-based stats.
Identities = 16/41 (39%), Positives = 24/41 (58%), Gaps = 4/41 (9%)
Frame = +2
Query: 335 QETYKRISRVEFTFPD----FVTEGARDLISRLLKHNPSQR 371
QET+ IS+V+ FPD ++ A+D I +LL +P R
Sbjct: 191 QETFCNISQVKLDFPDDLFSHISPHAKDFIKKLLVKDPRHR 313
>27274
Length = 396
Score = 49.7 bits (117), Expect = 2e-06, Method: Composition-based stats.
Identities = 30/97 (30%), Positives = 45/97 (46%), Gaps = 12/97 (12%)
Frame = -1
Query: 299 EMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEAN------------TYQETYKRISRVEF 346
E++ G+ H VD+WSLG+L +E L G PFE Y + + SR
Sbjct: 375 ELLRGQQHGPTVDMWSLGILLHELLSGHVPFEPERGSRQMARNMMAVYAQIIRGSSRDVC 196
Query: 347 TFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWI 383
T GA D + RL++ ++R ++ HPWI
Sbjct: 195 DGLALSTHGA-DFLRRLVQLEDTKRLTSQQAFSHPWI 88
>31120
Length = 439
Score = 48.9 bits (115), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 33/99 (33%), Positives = 53/99 (53%), Gaps = 6/99 (6%)
Frame = +1
Query: 299 EMIEGRMHDEKV-DLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTF----PDFVT 353
E++ G +D K+ D WSLGV+ + L GK PF+ + + + +++F D V+
Sbjct: 1 EVVCGVPYDPKMADAWSLGVILFIMLNGKMPFDDSNLNKLLEDQRSKKYSFRRKLQDLVS 180
Query: 354 EGARDLISRLLKHNPSQRPMLREVLEHPWI-TANSSKPS 391
AR +S LL+ N + R L EVL W+ T + +PS
Sbjct: 181 PNARSTVSVLLEPNSAMRWDLNEVLNCQWLQTIDEPRPS 297
>37602
Length = 804
Score = 48.5 bits (114), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 32/99 (32%), Positives = 46/99 (46%), Gaps = 3/99 (3%)
Frame = -1
Query: 189 RHPNILRLYGYFHDATR---VYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALS 245
R NI GYF R +++ +EY G++ E + A E L
Sbjct: 354 RIVNIQTFVGYFDSYLRREKLWIAMEYCGGGSMQDIYHVTGPLTEPQIAFVCRETLKGLH 175
Query: 246 YCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSS 284
Y H + +HRDIK N+LL G++K+ADF W V + S
Sbjct: 174 YLHRRGKMHRDIKGANILLTEEGDVKLADF-WRVSSNHS 61
>07833
Length = 1504
Score = 48.1 bits (113), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 45/213 (21%), Positives = 88/213 (41%), Gaps = 21/213 (9%)
Frame = -3
Query: 188 LRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKF--DEQRTATYITELANALS 245
HPN+L + + + LI ++ P G++Y L S D+ ++ + ++A +
Sbjct: 1448 FNHPNVLPVLACCNQPPNLVLISQFMPFGSLYNTLHGESGIVVDQNQSLRFAMDIARGME 1269
Query: 246 YCHSKRVIHRDIKPE--NLLLGS---------AGELKIADFGWSVHAPSSRRTTLCGTLD 294
+ HS ++P N LL S + +AD+ +S H +
Sbjct: 1268 FLHS-------MEPTIPNFLLTSKHVMIDEDLTARINMADYCFSFHEKGKVYSP-----A 1125
Query: 295 YLPPEMIEGRMHD---EKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISR--VEFTFP 349
++ PE ++ R D D+WS +L +E + PF + E +++ + + P
Sbjct: 1124 WMAPEALQRRPDDINTRAADMWSFAILMWELETREVPFAELSSMEVGMKVALEGLRISIP 945
Query: 350 DFVTEGARDLISRLLKHNPSQRP---MLREVLE 379
++ LI + P +RP M+ +LE
Sbjct: 944 PGISLHMSRLIKICMNEEPGKRPRFDMIIPILE 846
>32000
Length = 644
Score = 48.1 bits (113), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 39/148 (26%), Positives = 63/148 (42%), Gaps = 31/148 (20%)
Frame = -1
Query: 267 AGELKIADFGWS--VHAPSSRRTTLCGTLDYLPPEMIEG-RMHDEKVDLWSLGVLCYEFL 323
++KIADFG + P T TL Y PE++ G R + VD+WSLG + E +
Sbjct: 581 TAKMKIADFGLARVFGLPVRTYTHEVITLWYRAPEILLGCRFYSVPVDIWSLGCIFVEMM 402
Query: 324 VGKPPFEANTYQETYKRISRVEFT-----------FPDF-----------------VTEG 355
+ F ++ + RI R T PD+ +++
Sbjct: 401 TRRALFPGDSEIDQLYRIFRTLGTPDEKVWPGVSKLPDYKPTFPKWPLKNLETVVSLSKV 222
Query: 356 ARDLISRLLKHNPSQRPMLREVLEHPWI 383
DL+ R+L +NP++R R + HP+
Sbjct: 221 GLDLLKRMLTYNPNRRISARSAMRHPYF 138
>07291
Length = 833
Score = 47.8 bits (112), Expect = 8e-06, Method: Compositional matrix adjust.
Identities = 25/97 (25%), Positives = 50/97 (51%), Gaps = 6/97 (6%)
Frame = +1
Query: 239 ELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHA-PSSRRTT----LCGTL 293
++A+ ++Y +V+HR++ N ++ G L+++D+G + P S T +
Sbjct: 73 QIADGMAYLQEVKVVHRNLAARNCIVTEDGRLQLSDYGVTGSLFPQSYYTADDSPARDLV 252
Query: 294 DYLPPEMIEGRMHDEKVDLWSLGVLCYEFLV-GKPPF 329
++ PE I+ K D+W+ GV+ +E L G P+
Sbjct: 253 KWMAPETIDNFHFSSKSDVWAFGVVLWELLTRGITPY 363
>01106
Length = 878
Score = 46.6 bits (109), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 46/147 (31%), Positives = 70/147 (47%), Gaps = 15/147 (10%)
Frame = +3
Query: 133 FEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQ--LEKAGVEHQLRREVEIQSHLRH 190
+ + R LG G F V+L + K +ALKV+ AQ E A E +L + V +S +
Sbjct: 324 YHVIRKLGWGHFSTVWLCWDLTCKRFVALKVVKSAQHYTETALDEVKLLKCVR-ESDVAD 500
Query: 191 PNILRLYGYFHD-------ATRVYLILEYAPLGTVYRELQKLSKFDEQRTATY-----IT 238
P + D T V ++ E LG Y L+ + + + Q + I
Sbjct: 501 PARAKCVQLLDDFKISGVNGTHVAMVFEV--LG--YNLLKLIIRSNYQGIPIHNVKLIIR 668
Query: 239 ELANALSYCHSK-RVIHRDIKPENLLL 264
++ LSY H+K R+IH DIKPEN+L+
Sbjct: 669 QVLEGLSYMHAKCRIIHTDIKPENILI 749
>18481
Length = 437
Score = 44.7 bits (104), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 38/119 (31%), Positives = 57/119 (47%), Gaps = 7/119 (5%)
Frame = -1
Query: 167 AQLEKAGVEHQL-RREVEIQSHL-RHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQK 224
++E V+HQL E ++ + RHP + +Y Y + L++E LG EL
Sbjct: 395 VKIEAIDVKHQLLHYEAKVYEQIGRHPGLPTMYHYGTEKHFNALVME--LLGPSLEELFV 222
Query: 225 LSK--FDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLG---SAGELKIADFGWS 278
+ K F + +L + L + H K IHRD+KP+N L+G L I DFG S
Sbjct: 221 ICKRRFTLKTILMVSDQLLSRLEFIHQKCFIHRDLKPDNFLMGLGRHCHRLYIIDFGLS 45
>32957
Length = 645
Score = 44.7 bits (104), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 20/60 (33%), Positives = 32/60 (53%)
Frame = +3
Query: 275 FGWSVHAPSSRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTY 334
F V R T CGT +Y+ PE+ E + + ++VD W LG+L +E L + ++ Y
Sbjct: 3 FALCVEKSGGRTRTFCGTREYMAPEVHERKEYGKEVDWWGLGILLHELLAAQIKKHSSCY 182
>31489
Length = 329
Score = 43.9 bits (102), Expect = 1e-04, Method: Composition-based stats.
Identities = 23/88 (26%), Positives = 43/88 (48%), Gaps = 6/88 (6%)
Frame = +3
Query: 182 VEIQSHLRHPNI------LRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTAT 235
++I H +H NI L+ +HD ++++ + ++R + E+
Sbjct: 3 IKILKHFKHDNIISIREILKPKDSYHDFKDIHVVFDLME-SDLHRIIYSDQPLTEEHIRY 179
Query: 236 YITELANALSYCHSKRVIHRDIKPENLL 263
++ ++ L Y HS V+HRD+KP NLL
Sbjct: 180 FLYQILRGLKYIHSANVVHRDLKPSNLL 263
>16708
Length = 1397
Score = 43.9 bits (102), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 64/266 (24%), Positives = 100/266 (37%), Gaps = 33/266 (12%)
Frame = -1
Query: 139 LGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNIL-RLY 197
LGKG FG VY AR L KA L+ + + H EVE + L +++
Sbjct: 1379 LGKGVFGKVYEAR--------LLSTHEKAALKTSILCHHSLDEVEALGRIEGGFYLAQMF 1224
Query: 198 GY------FHDATRVYLILEYAPLGTVYRELQK----LSKFDEQRTATYITELANALSYC 247
G F + E PL VY + + + + AL +
Sbjct: 1223 GAWVTCLPFPKMNILLHFYEMGPLCNVYAHYKNKEMPIRWSNPAMVCCIAGQXVCALEHI 1044
Query: 248 HSKRVIHRDIKPENLLLGSAGELKIADFG----WSVH-APSSRRTTLCG---TLDYLPPE 299
H V+H D+K +N+L+ + G K+ D+G + V+ AP+ ++ C T PP
Sbjct: 1043 HELGVVHMDVKADNVLVDAHGNCKLTDYGIAQLYKVYPAPTETHSSGCTNKRTFYTRPPA 864
Query: 300 -MIEGRMHDEKVD------------LWSL-GVLCYEFLVGKPPFEANTYQETYKRISRVE 345
M E+ D LW+L G + V +PP + + R E
Sbjct: 863 TMTPSERFSEEGDGIGTDYFRLGQMLWTLTGAVLLHVWVSRPPKLPD-----WCRTPESE 699
Query: 346 FTFPDFVTEGARDLISRLLKHNPSQR 371
+ G D I +L +P+ R
Sbjct: 698 LS-------GMSDFIEKLCHGDPNMR 642
>17253
Length = 483
Score = 43.9 bits (102), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 27/112 (24%), Positives = 53/112 (47%), Gaps = 13/112 (11%)
Frame = -1
Query: 180 REVEIQSHL-RHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQK--------LSKFDE 230
RE+ I L RHPN++ G + +++E+ G + L+K L+
Sbjct: 402 RELSIMRKLPRHPNVVSFMGCCTMSDPALILMEFCCHGDLLSFLRKRRPDRTVFLTSTAN 223
Query: 231 QRTA----TYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS 278
TA ++ +A +++ + +++HRD+ N+L+ K++DFG S
Sbjct: 222 DLTARDFFSFALHVARGMAHVANNKIVHRDVAARNVLISERNVCKVSDFGLS 67
>20640
Length = 1492
Score = 43.5 bits (101), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 38/144 (26%), Positives = 65/144 (45%), Gaps = 5/144 (3%)
Frame = +1
Query: 253 IHRDIKPENLLLGSAGELKIADFGW--SVHAPSSRRTTLCGT--LDYLPPEMIEGRMHDE 308
+HRD+ N L+G +KI+DFG SVH+ R + + ++P E I
Sbjct: 10 VHRDLATRNCLVGHDLVVKISDFGLARSVHSVDYYRGSEHDAIPIRWMPLEAILYNKFST 189
Query: 309 KVDLWSLGVLCYE-FLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHN 367
+ D+WS GV+ +E F P+ T++E + FV EG ++L
Sbjct: 190 QSDVWSFGVVLWEIFAFALQPYYGLTHEEVVR-----------FVKEG------KVLACP 318
Query: 368 PSQRPMLREVLEHPWITANSSKPS 391
P + E+++ W +++PS
Sbjct: 319 ERTPPPMYELMKQCWHRRPATRPS 390
>07836
Length = 1478
Score = 42.7 bits (99), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 49/195 (25%), Positives = 85/195 (43%), Gaps = 31/195 (15%)
Frame = -1
Query: 159 LALKVLFKAQLEKAGVEHQLRREVEIQSH--LRHPNILRLYGY----FHDATRVYLILEY 212
+A+K+ F + E RE E+ LRH NIL T+++LI +Y
Sbjct: 1469 VAVKIFFTTE------EASWFRETELYQTVLLRHENILGFIAADIKGTGSWTQLFLITDY 1308
Query: 213 APLGTVYRELQKLSK-FDEQRTATYITELANALSYCHSK--------RVIHRDIKPENLL 263
G+++ L LS+ D L++ H + + HRDIK +N+L
Sbjct: 1307 HENGSLHDYL--LSRVLDSSEMLALAHSAICGLAHLHIEIFGTRGKPAIAHRDIKSKNIL 1134
Query: 264 LGSAGELKIADFGWSVH----------APSSRRTTLCGTLDYLPPEMIEGRMHD------ 307
+ G IAD G +V AP+ R+ GT Y+ PE++E ++
Sbjct: 1133 VKKNGTCCIADLGLAVRYISESNEVDVAPNPRQ----GTKRYMAPEVLEMLLNVKNFDAF 966
Query: 308 EKVDLWSLGVLCYEF 322
++ D+++ G++ +E
Sbjct: 965 KQADMYAFGLVMWEI 921
>20559
Length = 430
Score = 39.7 bits (91), Expect(2) = 3e-04, Method: Compositional matrix adjust.
Identities = 22/81 (27%), Positives = 45/81 (55%)
Frame = -2
Query: 130 LEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLR 189
++ +E +G+G +G V+ A+ +++ I+ALK + + + GV RE+ + L+
Sbjct: 378 MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRV-RLDDDDEGVPSSALREICLLKELK 202
Query: 190 HPNILRLYGYFHDATRVYLIL 210
H NI+RL+ H ++ L+
Sbjct: 201 HRNIVRLHDVLHSERKLTLVF 139
Score = 21.9 bits (45), Expect(2) = 3e-04, Method: Compositional matrix adjust.
Identities = 7/12 (58%), Positives = 9/12 (75%)
Frame = -1
Query: 244 LSYCHSKRVIHR 255
L +CHS V+HR
Sbjct: 37 LVFCHSNNVLHR 2
>17300
Length = 480
Score = 42.0 bits (97), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 29/98 (29%), Positives = 46/98 (46%), Gaps = 7/98 (7%)
Frame = +1
Query: 253 IHRDIKPENLLLGSAGELKIADFGWSVHAPSSRR----TTLCGTL--DYLPPEMIEGRMH 306
+HRD+ N+L+ K+ADFG S S TT G + + PE I R
Sbjct: 40 VHRDLAARNILVNEILVCKVADFGLSREIESDTTEGAYTTKGGKIPVRWTAPEAIAYRKF 219
Query: 307 DEKVDLWSLGVLCYEFL-VGKPPFEANTYQETYKRISR 343
D+WS GV+ +E + G+ P+ + Q+ K + +
Sbjct: 220 TSASDVWSFGVVMWEVMSYGERPYWNWSNQDVIKAVEK 333
>11404
Length = 563
Score = 40.8 bits (94), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 42/150 (28%), Positives = 71/150 (47%), Gaps = 12/150 (8%)
Frame = +1
Query: 127 QWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKV-------LFKAQLEKAGVEHQLR 179
+WA + +EI +GKG FG V A + +A+K+ L +AQ+E +E R
Sbjct: 130 KWA-DRYEIDSLIGKGSFGQVVKAYDHTDNEQVAIKIIKNKKPFLNQAQIEVKLLEMMNR 306
Query: 180 REVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKF---DEQRTATY 236
+ + + + I+RL +F R +L L + L +L + + F T +
Sbjct: 307 HDTDNKYY-----IVRLKRHF--MFRSHLCLVFELLSYNLYDLLRNTNFRGVSLNLTRKF 465
Query: 237 ITELANALSYCHS--KRVIHRDIKPENLLL 264
+L AL + + +IH D+KPEN+LL
Sbjct: 466 AQQLCTALLFLATPEMSIIHCDLKPENILL 555
>21210
Length = 518
Score = 40.4 bits (93), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 27/106 (25%), Positives = 49/106 (46%), Gaps = 13/106 (12%)
Frame = +3
Query: 291 GTLDYLPPEMIEGRM----HDEKVDLWSLGVLCYEFLVGKPPFE--ANTYQETYKRISRV 344
G Y+ PE I+ R +D + D+WSLG+ E G+ P+ + + + + + V
Sbjct: 6 GCRPYMAPERIDPRASSHGYDVRSDVWSLGITLMELATGRFPYRKWVSIFDQLQQVVRGV 185
Query: 345 EFTFP-------DFVTEGARDLISRLLKHNPSQRPMLREVLEHPWI 383
P DFV + +++ L + QRP ++L HP++
Sbjct: 186 APCLPHDGAFSHDFV-----NFVNKCLTKDEKQRPKYNKLLAHPFV 308
>21418
Length = 831
Score = 39.7 bits (91), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 20/56 (35%), Positives = 32/56 (57%), Gaps = 4/56 (7%)
Frame = +2
Query: 339 KRISRVEFTFPD----FVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKP 390
KRI ++ FPD V++ A+DLI +L +PS+R + +VL + WI + P
Sbjct: 8 KRIRSGQYDFPDPEWTNVSQAAKDLIKGMLNVDPSKRLCIEDVLRNKWIAQYDAVP 175
>20160
Length = 1277
Score = 38.5 bits (88), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 15/33 (45%), Positives = 24/33 (72%)
Frame = +2
Query: 354 EGARDLISRLLKHNPSQRPMLREVLEHPWITAN 386
E A DLI+R + +PS RP+L ++L+H W+T +
Sbjct: 332 EDAADLINRCIALDPSTRPVLADILKHKWMTKD 430
>00638
Length = 1595
Score = 38.1 bits (87), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 15/37 (40%), Positives = 21/37 (56%)
Frame = +2
Query: 223 QKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKP 259
Q F + Y+ EL AL +CHS ++HRD+KP
Sbjct: 392 QLYQTFTDYDIRFYLYELMKALDFCHSMGIMHRDVKP 502
>31789
Length = 676
Score = 36.6 bits (83), Expect = 0.018, Method: Compositional matrix adjust.
Identities = 27/103 (26%), Positives = 45/103 (43%), Gaps = 5/103 (4%)
Frame = +2
Query: 132 DFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHP 191
D EIGR G F VY + + +A L + K + + E E+ L+HP
Sbjct: 335 DVEIGR----GSFKTVYKGLDTELGVAVAWCELQDKKWNKT-ERQRFKEEAEMLKELQHP 499
Query: 192 NILRLYGYFHDATR-----VYLILEYAPLGTVYRELQKLSKFD 229
NI+R + Y+ + + L+ E GT+ L++ K +
Sbjct: 500 NIVRFFDYWEEHNHRNRKVIILVTELMTSGTLKTYLKRFKKIN 628
>36002
Length = 253
Score = 36.2 bits (82), Expect = 0.023, Method: Compositional matrix adjust.
Identities = 21/66 (31%), Positives = 31/66 (46%), Gaps = 5/66 (7%)
Frame = +1
Query: 324 VGKPPFEANTYQET-YKRISRVEFTFPDF----VTEGARDLISRLLKHNPSQRPMLREVL 378
V +P QE + RI + FP ++ A+DLI LL P +R +VL
Sbjct: 16 VAEPGEACQDCQELLFNRIQDGNYFFPSMEWSAISSSAKDLIRHLLVREPRKRYSAADVL 195
Query: 379 EHPWIT 384
+HPW+
Sbjct: 196 KHPWVC 213
>37063
Length = 455
Score = 35.4 bits (80), Expect = 0.043, Method: Compositional matrix adjust.
Identities = 23/77 (29%), Positives = 41/77 (53%), Gaps = 15/77 (19%)
Frame = -2
Query: 257 IKPENLLLGSAGE---LKIADF----GWSVHAPSSRRTTL---CGTLDYLPPEMIEGRM- 305
+KPEN+L E LKI DF G + ++ L G+ +Y+ PE+++ +
Sbjct: 454 LKPENILCEHLDEVVPLKICDFDLASGINCDGDGTKTPELLTPVGSAEYMAPEVVDAWVG 275
Query: 306 ----HDEKVDLWSLGVL 318
+D++ D+WSLG++
Sbjct: 274 ESFSYDKRCDMWSLGII 224
>20655
Length = 1181
Score = 34.7 bits (78), Expect = 0.068, Method: Compositional matrix adjust.
Identities = 17/56 (30%), Positives = 31/56 (55%), Gaps = 4/56 (7%)
Frame = +2
Query: 339 KRISRVEFTFP----DFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKP 390
KRI ++ FP V++ A+DLI +L +P +R +++V+ W+ N+ P
Sbjct: 8 KRIRNGQYEFPKPEWSRVSQDAKDLIRGMLCTDPDKRLNIKQVMASKWVADNTMVP 175
>00394
Length = 548
Score = 34.7 bits (78), Expect = 0.079, Method: Compositional matrix adjust.
Identities = 23/94 (24%), Positives = 43/94 (45%), Gaps = 5/94 (5%)
Frame = -2
Query: 137 RPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRL 196
+ +G+G F VY + + +A L + KA + + E E+ L+HPNI+R
Sbjct: 280 KEIGRGSFKTVYKGLDTELGVAVAWCELQDKKWNKAE-RQRFKEEAEMLKELQHPNIVRF 104
Query: 197 YGYFHDATR-----VYLILEYAPLGTVYRELQKL 225
+ Y+ + + L+ E GT+ L++
Sbjct: 103 FDYWEEHNHRNRKVIILVTELMTSGTLKTYLKRF 2
>18401
Length = 463
Score = 32.7 bits (73), Expect = 0.26, Method: Compositional matrix adjust.
Identities = 16/63 (25%), Positives = 29/63 (46%)
Frame = -3
Query: 287 TTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEF 346
+T+ T Y PE+I D+WS+G + +E G F+ + +E + R+
Sbjct: 458 STIVSTRHYRAPEVILELGWSHPCDVWSVGCIMFELYTGYTLFQTHDNKEHLAMMERILG 279
Query: 347 TFP 349
+ P
Sbjct: 278 SLP 270
>20773
Length = 391
Score = 32.0 bits (71), Expect = 0.48, Method: Compositional matrix adjust.
Identities = 17/54 (31%), Positives = 28/54 (51%)
Frame = -1
Query: 330 EANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWI 383
+ + ++R SR F VT+ +L+ RLL ++PSQR L HP++
Sbjct: 388 SGSCWSGLHRRRSRPVFPHTTVVTQHFYNLVQRLLTYDPSQRLTPDLALSHPFV 227
>21800
Length = 855
Score = 32.0 bits (71), Expect = 0.49, Method: Compositional matrix adjust.
Identities = 17/46 (36%), Positives = 26/46 (56%), Gaps = 5/46 (10%)
Frame = +2
Query: 237 ITELANALSYCHSK-RVIHRDIKPENLLLGSAG----ELKIADFGW 277
I ++ L+Y H+K +IH DIKPEN+L+ +L + F W
Sbjct: 650 IRQVLEGLNYLHAKCNIIHTDIKPENILICVDDNYIRKLAVDAFEW 787
>36481
Length = 806
Score = 32.0 bits (71), Expect = 0.51, Method: Compositional matrix adjust.
Identities = 32/141 (22%), Positives = 65/141 (46%), Gaps = 8/141 (5%)
Frame = +2
Query: 132 DFEIGRPLGKGKFGNVYLAREKQSKFILALKVL--FKAQLEKAGVE-HQLRREVEIQSHL 188
D ++ G+G FG V ++ +ALK++ E A +E + L + E H
Sbjct: 365 DMKLCPHWGEGTFGKVVQCKDLLKGDDIALKIIKNVDKYREAAKLEINVLEKLREKDPHA 544
Query: 189 RHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKF-----DEQRTATYITELANA 243
+H + L + + ++ + + LG + K + + ++ R +Y +L A
Sbjct: 545 KHMCVQMLDWFDYHG---HVCISFHMLGLSVFDFLKDNSYGAYPIEQVRHISY--QLCYA 709
Query: 244 LSYCHSKRVIHRDIKPENLLL 264
+++ H ++ H D+KPEN+L
Sbjct: 710 VNFLHENQLTHTDLKPENILF 772
>19872
Length = 446
Score = 31.6 bits (70), Expect = 0.53, Method: Compositional matrix adjust.
Identities = 14/41 (34%), Positives = 25/41 (60%), Gaps = 4/41 (9%)
Frame = +3
Query: 349 PDFVTEGA----RDLISRLLKHNPSQRPMLREVLEHPWITA 385
PDF + L+ ++L H+P+QRP R++L+ P++ A
Sbjct: 99 PDFTKDADLHNQSALLRQMLSHDPTQRPSSRDLLQSPYLPA 221
>17932
Length = 597
Score = 28.1 bits (61), Expect(2) = 0.76, Method: Compositional matrix adjust.
Identities = 14/31 (45%), Positives = 16/31 (51%), Gaps = 2/31 (6%)
Frame = -2
Query: 313 WSLGVLCYEFLVGKPPF--EANTYQETYKRI 341
WSLGV YE L G PF + + TY I
Sbjct: 593 WSLGVCAYEMLFGCTPFTDDDGSMVATYNNI 501
Score = 21.6 bits (44), Expect(2) = 0.76, Method: Compositional matrix adjust.
Identities = 14/32 (43%), Positives = 20/32 (62%)
Frame = -3
Query: 352 VTEGARDLISRLLKHNPSQRPMLREVLEHPWI 383
V++ ARDLIS+LL S R E+ +HP+
Sbjct: 460 VSKEARDLISQLLSDGKS-RLGWPELQQHPFF 368
>16350
Length = 1108
Score = 29.6 bits (65), Expect = 2.1, Method: Compositional matrix adjust.
Identities = 12/39 (30%), Positives = 23/39 (58%), Gaps = 1/39 (2%)
Frame = +3
Query: 358 DLISRLLKHNPSQRPMLREVLEHPWITANS-SKPSNCQN 395
D ++ +L+ +P QR + L+HPW+ ++ +PS Q
Sbjct: 762 DFLAPMLEFDPEQRATAAQSLQHPWLKLDA*PEPSGSQQ 878
>20513
Length = 405
Score = 29.3 bits (64), Expect = 2.9, Method: Compositional matrix adjust.
Identities = 12/39 (30%), Positives = 23/39 (58%), Gaps = 1/39 (2%)
Frame = -1
Query: 358 DLISRLLKHNPSQRPMLREVLEHPWITANS-SKPSNCQN 395
D ++ +L+ +P QR + L+HPW+ ++ +PS Q
Sbjct: 282 DFLAPMLEFDPEQRATAAQSLQHPWLKLDA*PEPSGSQQ 166
>17644
Length = 463
Score = 27.7 bits (60), Expect = 8.1, Method: Compositional matrix adjust.
Identities = 13/32 (40%), Positives = 19/32 (59%)
Frame = +3
Query: 352 VTEGARDLISRLLKHNPSQRPMLREVLEHPWI 383
VT+ BL+ RLL ++PSQR L HP++
Sbjct: 69 VTQHFYBLVQRLLTYDPSQRLTPDLALSHPFV 164
>18929
Length = 440
Score = 27.7 bits (60), Expect = 9.8, Method: Compositional matrix adjust.
Identities = 11/38 (28%), Positives = 22/38 (57%)
Frame = +1
Query: 348 FPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITA 385
F + ++ + +I R++ +P QRP ++L HP + A
Sbjct: 34 FINTISVELQQVIRRMMSPDPRQRPTANQLLAHPTLAA 147
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000255465 | hsapiens_gene_ensembl | Cyclin-A1.
[Source:Uniprot/SWISSPROT;Acc:P78396]
(465 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
11451 256 1e-68
16444 181 4e-46
25961 116 2e-26
38040 30 1.5
19735 28 7.1
>11451
Length = 1321
Score = 256 bits (654), Expect = 1e-68, Method: Compositional matrix adjust.
Identities = 130/256 (50%), Positives = 170/256 (66%), Gaps = 1/256 (0%)
Frame = +2
Query: 202 GTDVINVTEYAEEIYQYLREAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLR 261
T + V EYAE+IY YL E ++RP+ +MK+Q D+T MR ILVDWLVEV EEYKL+
Sbjct: 467 ATIIEEVPEYAEDIYSYLLSVEHKNRPRPGFMKRQEDVTMAMRAILVDWLVEVAEEYKLQ 646
Query: 262 AETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTX 321
ETL+L V F+DRFL+ MSVLR KLQLVG AAM LA+KYEEIYPP+V+EFVYITDDT
Sbjct: 647 RETLFLTVTFIDRFLAHMSVLRSKLQLVGAAAMFLAAKYEEIYPPDVNEFVYITDDTXQK 826
Query: 322 XXXXXXXXXXXXXXAFDLTVPTTNQFLLQYLRRQGVCVRTENLAKYVAELSLLEADPFLK 381
FD++ PT N F + LR+ +NL Y+ EL L+E + +L
Sbjct: 827 KQILRMEHLILKVLKFDISTPTVNWFSERLLRKVKAEDSLKNLTMYLCELVLVEYEKYLV 1006
Query: 382 YLPSLIAAAAFCLANYTVN-KHFWPETLAAFTGYSLSEIVPCLSELHKAYLDIPHRPQQA 440
+ SL+AA+A CLANYT++ +HFW + YSLS+++PC+ L+ + I H PQQA
Sbjct: 1007FPNSLVAASALCLANYTLHQQHFWSAEHERVSSYSLSQLLPCVQMLYDMHCHIEHHPQQA 1186
Query: 441 IREKYKASKYLCVSLM 456
+REKY+ SKY V+ M
Sbjct: 1187VREKYRLSKYDSVADM 1234
>16444
Length = 2113
Score = 181 bits (460), Expect = 4e-46, Method: Compositional matrix adjust.
Identities = 101/242 (41%), Positives = 143/242 (59%), Gaps = 1/242 (0%)
Frame = -2
Query: 224 IRHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLR 283
+R+RP+ +M QP++T MRTILVDWLVE+G+E+++ E L+LAV LDR+L+ + V R
Sbjct: 1269 MRNRPQQGFMGHQPELTLTMRTILVDWLVELGDEFEVCHEGLFLAVKILDRYLAQVKVNR 1090
Query: 284 GKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTXXXXXXXXXXXXXXXAFDLTVPT 343
LQLVG AA LASKYEEIYPP V++ Y+TDDT T DL P+
Sbjct: 1089 CNLQLVGAAAFFLASKYEEIYPPCVEDIAYMTDDTCTARQVLRMERRIFVKLDHDLNGPS 910
Query: 344 TNQFLLQYLRRQGVCVRTENLAKYVAELSLLEADPFLKYLPSLIAAAAFCLANYTV-NKH 402
F + + G E L ++ L+ L D FL+Y PS+IAA+AFCLA YT+ ++
Sbjct: 909 IGWFAQRLCKVTGSPENLEQLTMFLCYLAXLHIDXFLEYPPSIIAASAFCLARYTLRDRT 730
Query: 403 FWPETLAAFTGYSLSEIVPCLSELHKAYLDIPHRPQQAIREKYKASKYLCVSLMEPPAVL 462
W + Y L E++ C+ EL+ AYL+ QQA + K+ ++ VS + PP L
Sbjct: 729 PWDRLCVMKSQYYLHELLSCIDELYAAYLESFQSQQQACQNKFGKERFGMVSRIPPPQQL 550
Query: 463 LL 464
+L
Sbjct: 549 IL 544
>25961
Length = 538
Score = 116 bits (290), Expect = 2e-26, Method: Compositional matrix adjust.
Identities = 59/112 (52%), Positives = 77/112 (68%)
Frame = -1
Query: 208 VTEYAEEIYQYLREAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYL 267
V+EY +IY Y+R+ E R +A Y++ DIT MR ILVDWL +V + L ETLYL
Sbjct: 520 VSEYVNDIYDYMRQMEQRLCVRASYLEG-TDITGKMRCILVDWLCQVHHRFHLLQETLYL 344
Query: 268 AVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTY 319
V+ +DRFL V R KLQLVG +ML+ASKYEE++ PEV +FVYI+D+ Y
Sbjct: 343 TVSIMDRFLQQKPVTRNKLQLVGVTSMLVASKYEELFAPEVADFVYISDNAY 188
>38040
Length = 374
Score = 30.4 bits (67), Expect = 1.5, Method: Compositional matrix adjust.
Identities = 16/55 (29%), Positives = 27/55 (49%)
Frame = +2
Query: 404 WPETLAAFTGYSLSEIVPCLSELHKAYLDIPHRPQQAIREKYKASKYLCVSLMEP 458
W TL +TGY L E+ P + EL+ + +R+KY+ + V+ + P
Sbjct: 14 WTPTLHFYTGYRLKELKPLILELNTMLCSKRYPDLVTVRDKYRHHLFHSVAEIAP 178
>19735
Length = 1559
Score = 28.1 bits (61), Expect = 7.1, Method: Compositional matrix adjust.
Identities = 20/80 (25%), Positives = 38/80 (47%)
Frame = -1
Query: 238 DITEGMRTILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLA 297
+IT+ R W+++ + ET LA++ +DR + + + L+ V + + +A
Sbjct: 1532 EITDMERDKEALWIIQQSRSFDFAPETYALAISIMDRVSTLVKIRPKYLRCVAISCLFIA 1353
Query: 298 SKYEEIYPPEVDEFVYITDD 317
+K E DE + IT D
Sbjct: 1352 AK-----TLEDDETIPITLD 1308
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000365365 | hsapiens_gene_ensembl |
CLIP-associating protein 1 (Cytoplasmic linker-associated protein 1)
(Multiple asters homolog 1) (hOrbit1).
[Source:Uniprot/SWISSPROT;Acc:Q7Z460]
(1273 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
25317 252 4e-68
13482 169 5e-42
27421 59 2e-08
24313 33 0.67
>25317
Length = 1017
Score = 252 bits (644), Expect(2) = 4e-68, Method: Compositional matrix adjust.
Identities = 114/229 (49%), Positives = 165/229 (72%)
Frame = +2
Query: 88 VPVVQIYSSRDLEESINKIREILSDDKHDWEQRVNALKKIRSLLLAGAAEYDNFFQHLRL 147
+ ++Q++SSRD+ + ++K+ LSD DWE+RV+ K R+L++ GA ++D F Q LR
Sbjct: 56 IALLQLFSSRDMMDQMSKVNAALSDANLDWEKRVDNFKIFRALVMNGATDHDEFHQQLRG 235
Query: 148 LDGAFKLSAKDLRSQVVREACITLGHLSSVLGNKFDHGAEAIMPTIFNLIPNSAKIMATS 207
++ AF KDLRSQVVREAC+T+ +++ LG+K D AE + P +FNLIPNSAKIMATS
Sbjct: 236 MEPAFVSGVKDLRSQVVREACVTIAYMAQQLGSKLDRFAEVVFPALFNLIPNSAKIMATS 415
Query: 208 GVVAVRLIIRHTHIPRLIPVITSNCTSKSVAVRRRCFEFLDLLLQEWQTHSLERHISVLA 267
G V +R II++ H RLIP++T N ++KS +RR+ EFL+ LL W TH+LE+HI++L
Sbjct: 416 GCVCIRFIIQYVHTNRLIPILTGNMSTKSNVIRRQSCEFLNQLLHSWGTHTLEKHIALLQ 595
Query: 268 ETIKKGIHDADSEARIEARKCYWGFHSHFSREAEHLYHTLESSYQKALQ 316
++I++GI DADSEAR +RK +WGF HF +A+ L +L+ S QK LQ
Sbjct: 596 DSIRRGISDADSEARAFSRKAFWGFAEHFKSQADALLASLDPSKQKLLQ 742
Score = 26.2 bits (56), Expect(2) = 4e-68, Method: Composition-based stats.
Identities = 11/16 (68%), Positives = 14/16 (87%)
Frame = +1
Query: 77 DEEDFIKAFDDVPVVQ 92
DEE FIK+F+DVP V+
Sbjct: 7 DEELFIKSFEDVPKVK 54
>13482
Length = 530
Score = 169 bits (429), Expect = 5e-42, Method: Compositional matrix adjust.
Identities = 78/150 (52%), Positives = 108/150 (72%)
Frame = +2
Query: 77 DEEDFIKAFDDVPVVQIYSSRDLEESINKIREILSDDKHDWEQRVNALKKIRSLLLAGAA 136
DEE FIK+F+DVP V+++SSRD+ + ++K+ LSD DWE+RV+ K R+L++ GA
Sbjct: 80 DEELFIKSFEDVPKVKLFSSRDMMDQMSKVNAALSDANLDWEKRVDNFKIFRALVMNGAT 259
Query: 137 EYDNFFQHLRLLDGAFKLSAKDLRSQVVREACITLGHLSSVLGNKFDHGAEAIMPTIFNL 196
++D F Q LR ++ AF KDLRSQVVREAC+T+ +++ LG+K D AE + P +FNL
Sbjct: 260 DHDEFHQQLRGMEPAFVSGVKDLRSQVVREACVTIAYMAQQLGSKLDRFAEVVFPALFNL 439
Query: 197 IPNSAKIMATSGVVAVRLIIRHTHIPRLIP 226
IPNSAKIMATSG V +R II++ H R P
Sbjct: 440 IPNSAKIMATSGCVCIRFIIQYVHTNRQTP 529
>27421
Length = 374
Score = 58.5 bits (140), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 40/103 (38%), Positives = 54/103 (52%), Gaps = 2/103 (1%)
Frame = -3
Query: 489 VTPSSEKRSKIPRSQGCSRETSPNR--IGLDRFGLGQPGRIPGSVNAMRVLSTSTDLEAA 546
+TP ++++ IPRSQG SRE SPNR G +R G G G + + RVL +D+E A
Sbjct: 276 MTPKGKRKTGIPRSQGASREASPNRRTYGRERRLSGSKGSHTGPLISQRVLRPGSDVEDA 97
Query: 547 VADALVRGTSTGKKKPVRRRYEPYGMYXXXXXXXXXXXVCSER 589
+ DAL R P R+RY+ +Y VCSER
Sbjct: 96 LHDALSR--------PNRKRYD---VYDSDDAASETSSVCSER 1
>24313
Length = 937
Score = 33.1 bits (74), Expect = 0.67, Method: Composition-based stats.
Identities = 19/43 (44%), Positives = 27/43 (62%), Gaps = 1/43 (2%)
Frame = -3
Query: 639 TLSRVELKRLCEIF-TRMFADPHSKIADSEAECEDKEGNLFPS 680
T V+L LC+ F TR+F+D HS++ DS+A+C FPS
Sbjct: 314 TPCHVQL*LLCQQFHTRVFSDQHSRLHDSDAQC-------FPS 207
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000195419 | hsapiens_gene_ensembl | Exportin-1
(Exp1) (Chromosome region maintenance 1 protein homolog).
[Source:Uniprot/SWISSPROT;Acc:O14980]
(1071 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
09530 255 5e-68
38734 33 0.61
21946 30 3.7
31761 30 4.3
>09530
Length = 971
Score = 255 bits (652), Expect = 5e-68, Method: Compositional matrix adjust.
Identities = 122/179 (68%), Positives = 146/179 (81%), Gaps = 1/179 (0%)
Frame = +2
Query: 894 LQILFTLLQNVAQEEAAAQSFYQTYFCDILQHIFSVVTDTSHTAGLTMHASILAYMFNLV 953
L IL+TLLQN+A EE AAQSFYQTYF DILQH+FSV+TD+SHTAGLTM A+ILA MF +
Sbjct: 2 LDILYTLLQNIAGEEVAAQSFYQTYFTDILQHLFSVITDSSHTAGLTMQATILATMFVAL 181
Query: 954 EEGKISTSLNPGN-PVNNQIFLQEYVANLLKSAFPHLQDAQVKLFVTGLFSLNQDIPAFK 1012
E KI+ L+P + P N ++Q+++ NLLK+AFPHL + Q+KLF+ GLFS +QD AFK
Sbjct: 182 ESNKITAPLSPNHAPAQNVAYIQDFLLNLLKTAFPHLNEPQIKLFIEGLFSFDQDFNAFK 361
Query: 1013 EHLRDFLVQIKEFAGEDTSDLFLEEREIALRQADEEKHKRQMSVPGIFNPHEIPEEMCD 1071
EHLRDFLVQI+EFAGED SDLFLEERE A+RQA +EK K QM+VPGI PHEIPEEM D
Sbjct: 362 EHLRDFLVQIREFAGEDMSDLFLEERETAIRQAQDEKRKVQMAVPGILGPHEIPEEMQD 538
>38734
Length = 605
Score = 33.1 bits (74), Expect = 0.61, Method: Compositional matrix adjust.
Identities = 20/59 (33%), Positives = 34/59 (57%), Gaps = 1/59 (1%)
Frame = +3
Query: 976 EYVANLLKSAFPHLQDAQVKL-FVTGLFSLNQDIPAFKEHLRDFLVQIKEFAGEDTSDL 1033
EY NL K + +Q AQ +L + + +LN ++ A K+HL + L Q+K+ ED ++
Sbjct: 207 EYFRNLYKRSEVAVQQAQEELAMLRSVKALNVELIASKQHLMEELAQVKKLRKEDQEEM 383
>21946
Length = 569
Score = 30.4 bits (67), Expect = 3.7, Method: Composition-based stats.
Identities = 13/42 (30%), Positives = 23/42 (54%), Gaps = 3/42 (7%)
Frame = -2
Query: 559 WKFLKTVV---NKLFEFMHETHDGVQDMACDTFIKIAQKCRR 597
W L T++ ++ F H+TH V+D C + I ++C+R
Sbjct: 196 WCLLSTIIQTCHQRLRFEHDTHCAVRDSCCREWYVIFRRCQR 71
>31761
Length = 1165
Score = 30.4 bits (67), Expect = 4.3, Method: Compositional matrix adjust.
Identities = 14/46 (30%), Positives = 25/46 (54%)
Frame = -2
Query: 588 FIKIAQKCRRHFVQVQVGEVMPFIDEILNNINTIICDLQPQQVHTF 633
+K K ++Q +V + +PFID+ L N+ +IC + VH +
Sbjct: 1128 LLKFINKVDDPYIQCKVSQTLPFIDQHLVNLR*LICYISNLGVHIW 991
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000380717 | hsapiens_gene_ensembl |
CLIP-associating protein 1 (Cytoplasmic linker-associated protein 1)
(Multiple asters homolog 1) (hOrbit1).
[Source:Uniprot/SWISSPROT;Acc:Q7Z460]
(1471 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
25317 252 5e-68
13482 169 5e-42
27718 102 3e-29
27421 59 2e-08
21443 35 0.19
20120 35 0.21
00036 31 4.4
>25317
Length = 1017
Score = 252 bits (643), Expect(2) = 5e-68, Method: Compositional matrix adjust.
Identities = 114/229 (49%), Positives = 165/229 (72%)
Frame = +2
Query: 309 VPVVQIYSSRDLEESINKIREILSDDKHDWEQRVNALKKIRSLLLAGAAEYDNFFQHLRL 368
+ ++Q++SSRD+ + ++K+ LSD DWE+RV+ K R+L++ GA ++D F Q LR
Sbjct: 56 IALLQLFSSRDMMDQMSKVNAALSDANLDWEKRVDNFKIFRALVMNGATDHDEFHQQLRG 235
Query: 369 LDGAFKLSAKDLRSQVVREACITLGHLSSVLGNKFDHGAEAIMPTIFNLIPNSAKIMATS 428
++ AF KDLRSQVVREAC+T+ +++ LG+K D AE + P +FNLIPNSAKIMATS
Sbjct: 236 MEPAFVSGVKDLRSQVVREACVTIAYMAQQLGSKLDRFAEVVFPALFNLIPNSAKIMATS 415
Query: 429 GVVAVRLIIRHTHIPRLIPVITSNCTSKSVAVRRRCFEFLDLLLQEWQTHSLERHISVLA 488
G V +R II++ H RLIP++T N ++KS +RR+ EFL+ LL W TH+LE+HI++L
Sbjct: 416 GCVCIRFIIQYVHTNRLIPILTGNMSTKSNVIRRQSCEFLNQLLHSWGTHTLEKHIALLQ 595
Query: 489 ETIKKGIHDADSEARIEARKCYWGFHSHFSREAEHLYHTLESSYQKALQ 537
++I++GI DADSEAR +RK +WGF HF +A+ L +L+ S QK LQ
Sbjct: 596 DSIRRGISDADSEARAFSRKAFWGFAEHFKSQADALLASLDPSKQKLLQ 742
Score = 26.6 bits (57), Expect(2) = 5e-68, Method: Composition-based stats.
Identities = 11/16 (68%), Positives = 14/16 (87%)
Frame = +1
Query: 298 DEEDFIKAFDDVPVVQ 313
DEE FIK+F+DVP V+
Sbjct: 7 DEELFIKSFEDVPKVK 54
>13482
Length = 530
Score = 169 bits (429), Expect = 5e-42, Method: Compositional matrix adjust.
Identities = 78/150 (52%), Positives = 108/150 (72%)
Frame = +2
Query: 298 DEEDFIKAFDDVPVVQIYSSRDLEESINKIREILSDDKHDWEQRVNALKKIRSLLLAGAA 357
DEE FIK+F+DVP V+++SSRD+ + ++K+ LSD DWE+RV+ K R+L++ GA
Sbjct: 80 DEELFIKSFEDVPKVKLFSSRDMMDQMSKVNAALSDANLDWEKRVDNFKIFRALVMNGAT 259
Query: 358 EYDNFFQHLRLLDGAFKLSAKDLRSQVVREACITLGHLSSVLGNKFDHGAEAIMPTIFNL 417
++D F Q LR ++ AF KDLRSQVVREAC+T+ +++ LG+K D AE + P +FNL
Sbjct: 260 DHDEFHQQLRGMEPAFVSGVKDLRSQVVREACVTIAYMAQQLGSKLDRFAEVVFPALFNL 439
Query: 418 IPNSAKIMATSGVVAVRLIIRHTHIPRLIP 447
IPNSAKIMATSG V +R II++ H R P
Sbjct: 440 IPNSAKIMATSGCVCIRFIIQYVHTNRQTP 529
>27718
Length = 388
Score = 102 bits (254), Expect(2) = 3e-29, Method: Composition-based stats.
Identities = 50/87 (57%), Positives = 64/87 (73%)
Frame = -3
Query: 112 QTLLLKIMDQAANPQYVWDRMLGGFKHKNFRTREGICLCLIATLNASGAQTLTLSKIVPH 171
Q LLLK+M A++PQYV++RM G F HK + REG+ +CL T+N GA++L LSK VP
Sbjct: 263 QQLLLKLMMPASSPQYVFERMSGAFSHKLWHVREGMLVCLQNTINRYGARSLQLSKTVPA 84
Query: 172 ICNLLGDPNSQVRDAAINSLVEIYRHV 198
IC LL D N QVR+AA+ +L EIYRHV
Sbjct: 83 ICKLLEDQNLQVREAAVVTLTEIYRHV 3
Score = 45.8 bits (107), Expect(2) = 3e-29, Method: Compositional matrix adjust.
Identities = 21/28 (75%), Positives = 23/28 (82%)
Frame = -1
Query: 83 DRFKAQIGTVLPSLIDRLGDAKDSVREQ 110
+ FK I TVLPS+IDRLGDAKD VREQ
Sbjct: 349 EEFKPHISTVLPSVIDRLGDAKDQVREQ 266
>27421
Length = 374
Score = 58.5 bits (140), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 40/103 (38%), Positives = 54/103 (52%), Gaps = 2/103 (1%)
Frame = -3
Query: 710 VTPSSEKRSKIPRSQGCSRETSPNR--IGLDRFGLGQPGRIPGSVNAMRVLSTSTDLEAA 767
+TP ++++ IPRSQG SRE SPNR G +R G G G + + RVL +D+E A
Sbjct: 276 MTPKGKRKTGIPRSQGASREASPNRRTYGRERRLSGSKGSHTGPLISQRVLRPGSDVEDA 97
Query: 768 VADALVRGTSTGKKKPVRRRYEPYGMYXXXXXXXXXXXVCSER 810
+ DAL R P R+RY+ +Y VCSER
Sbjct: 96 LHDALSR--------PNRKRYD---VYDSDDAASETSSVCSER 1
>21443
Length = 610
Score = 35.4 bits (80), Expect = 0.19, Method: Compositional matrix adjust.
Identities = 19/59 (32%), Positives = 31/59 (52%)
Frame = -1
Query: 138 HKNFRTREGICLCLIATLNASGAQTLTLSKIVPHICNLLGDPNSQVRDAAINSLVEIYR 196
H N + ICL + L + + LT+SK++ IC++L DPN D + + IY+
Sbjct: 313 HPNINSNGSICLDI---LRSQWSPALTISKVLLSICSMLTDPNPD--DPLVPEIARIYK 152
>20120
Length = 1816
Score = 35.0 bits (79), Expect = 0.21, Method: Compositional matrix adjust.
Identities = 33/117 (28%), Positives = 47/117 (40%), Gaps = 20/117 (17%)
Frame = +3
Query: 108 REQDQTLLLKIMDQAANPQYVWDRMLGGFKHKNFRTREGICLC----------------- 150
R DQ+ L + A V D+ L + K +R E ICLC
Sbjct: 549 RYTDQSHLRTLYTLAEQHVQVSDKAL---QKKAYRILEEICLCESEACREFLMSNLTEIQ 719
Query: 151 --LIATLNASGAQTLTLS-KIVPHICNLLGDPNSQVRDAAINSLVEIYRHVGERVRA 204
L+ +L+AS T + + IC L PN+ A + + R VGE+VRA
Sbjct: 720 QLLLGSLSASAPNTRNPRLRCLTCICQQLTQPNTAFIQAVVPEAIMCTRGVGEKVRA 890
>00036
Length = 1324
Score = 30.8 bits (68), Expect = 4.4, Method: Composition-based stats.
Identities = 14/29 (48%), Positives = 18/29 (62%)
Frame = +3
Query: 64 YKVVLLGMDILSALVTRLQDRFKAQIGTV 92
YK V+ +DI +TRL D FK +GTV
Sbjct: 1185 YKQVMFHLDIFHCGITRLTDYFKFPMGTV 1271
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000263710 | hsapiens_gene_ensembl |
CLIP-associating protein 1 (Cytoplasmic linker-associated protein 1)
(Multiple asters homolog 1) (hOrbit1).
[Source:Uniprot/SWISSPROT;Acc:Q7Z460]
(1538 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
25317 251 6e-68
13482 169 8e-42
27718 102 4e-29
27421 53 9e-07
21443 35 0.24
20120 35 0.25
00036 31 4.6
>25317
Length = 1017
Score = 251 bits (642), Expect(2) = 6e-68, Method: Compositional matrix adjust.
Identities = 114/229 (49%), Positives = 165/229 (72%)
Frame = +2
Query: 309 VPVVQIYSSRDLEESINKIREILSDDKHDWEQRVNALKKIRSLLLAGAAEYDNFFQHLRL 368
+ ++Q++SSRD+ + ++K+ LSD DWE+RV+ K R+L++ GA ++D F Q LR
Sbjct: 56 IALLQLFSSRDMMDQMSKVNAALSDANLDWEKRVDNFKIFRALVMNGATDHDEFHQQLRG 235
Query: 369 LDGAFKLSAKDLRSQVVREACITLGHLSSVLGNKFDHGAEAIMPTIFNLIPNSAKIMATS 428
++ AF KDLRSQVVREAC+T+ +++ LG+K D AE + P +FNLIPNSAKIMATS
Sbjct: 236 MEPAFVSGVKDLRSQVVREACVTIAYMAQQLGSKLDRFAEVVFPALFNLIPNSAKIMATS 415
Query: 429 GVVAVRLIIRHTHIPRLIPVITSNCTSKSVAVRRRCFEFLDLLLQEWQTHSLERHISVLA 488
G V +R II++ H RLIP++T N ++KS +RR+ EFL+ LL W TH+LE+HI++L
Sbjct: 416 GCVCIRFIIQYVHTNRLIPILTGNMSTKSNVIRRQSCEFLNQLLHSWGTHTLEKHIALLQ 595
Query: 489 ETIKKGIHDADSEARIEARKCYWGFHSHFSREAEHLYHTLESSYQKALQ 537
++I++GI DADSEAR +RK +WGF HF +A+ L +L+ S QK LQ
Sbjct: 596 DSIRRGISDADSEARAFSRKAFWGFAEHFKSQADALLASLDPSKQKLLQ 742
Score = 26.6 bits (57), Expect(2) = 6e-68, Method: Composition-based stats.
Identities = 11/16 (68%), Positives = 14/16 (87%)
Frame = +1
Query: 298 DEEDFIKAFDDVPVVQ 313
DEE FIK+F+DVP V+
Sbjct: 7 DEELFIKSFEDVPKVK 54
>13482
Length = 530
Score = 169 bits (428), Expect = 8e-42, Method: Compositional matrix adjust.
Identities = 78/150 (52%), Positives = 108/150 (72%)
Frame = +2
Query: 298 DEEDFIKAFDDVPVVQIYSSRDLEESINKIREILSDDKHDWEQRVNALKKIRSLLLAGAA 357
DEE FIK+F+DVP V+++SSRD+ + ++K+ LSD DWE+RV+ K R+L++ GA
Sbjct: 80 DEELFIKSFEDVPKVKLFSSRDMMDQMSKVNAALSDANLDWEKRVDNFKIFRALVMNGAT 259
Query: 358 EYDNFFQHLRLLDGAFKLSAKDLRSQVVREACITLGHLSSVLGNKFDHGAEAIMPTIFNL 417
++D F Q LR ++ AF KDLRSQVVREAC+T+ +++ LG+K D AE + P +FNL
Sbjct: 260 DHDEFHQQLRGMEPAFVSGVKDLRSQVVREACVTIAYMAQQLGSKLDRFAEVVFPALFNL 439
Query: 418 IPNSAKIMATSGVVAVRLIIRHTHIPRLIP 447
IPNSAKIMATSG V +R II++ H R P
Sbjct: 440 IPNSAKIMATSGCVCIRFIIQYVHTNRQTP 529
>27718
Length = 388
Score = 102 bits (254), Expect(2) = 4e-29, Method: Composition-based stats.
Identities = 50/87 (57%), Positives = 64/87 (73%)
Frame = -3
Query: 112 QTLLLKIMDQAANPQYVWDRMLGGFKHKNFRTREGICLCLIATLNASGAQTLTLSKIVPH 171
Q LLLK+M A++PQYV++RM G F HK + REG+ +CL T+N GA++L LSK VP
Sbjct: 263 QQLLLKLMMPASSPQYVFERMSGAFSHKLWHVREGMLVCLQNTINRYGARSLQLSKTVPA 84
Query: 172 ICNLLGDPNSQVRDAAINSLVEIYRHV 198
IC LL D N QVR+AA+ +L EIYRHV
Sbjct: 83 ICKLLEDQNLQVREAAVVTLTEIYRHV 3
Score = 45.8 bits (107), Expect(2) = 4e-29, Method: Compositional matrix adjust.
Identities = 21/28 (75%), Positives = 23/28 (82%)
Frame = -1
Query: 83 DRFKAQIGTVLPSLIDRLGDAKDSVREQ 110
+ FK I TVLPS+IDRLGDAKD VREQ
Sbjct: 349 EEFKPHISTVLPSVIDRLGDAKDQVREQ 266
>27421
Length = 374
Score = 53.1 bits (126), Expect = 9e-07, Method: Compositional matrix adjust.
Identities = 39/129 (30%), Positives = 54/129 (41%)
Frame = -3
Query: 710 VTPSSEKRSKIPRSQGCSRETSPNRIGLARSSRIPRPSMSQGCXXXXXXXXXXXXXPARG 769
+TP ++++ IPRSQG SRE SPNR R R+
Sbjct: 276 MTPKGKRKTGIPRSQGASREASPNRRTYGRERRL-------------------------- 175
Query: 770 FPPLDRFGLGQPGRIPGSVNAMRVLSTSTDLEAAVADALKKPVRRRYEPYGMYXXXXXXX 829
G G G + + RVL +D+E A+ DAL +P R+RY+ +Y
Sbjct: 174 --------SGSKGSHTGPLISQRVLRPGSDVEDALHDALSRPNRKRYD---VYDSDDAAS 28
Query: 830 XXXXVCSER 838
VCSER
Sbjct: 27 ETSSVCSER 1
>21443
Length = 610
Score = 35.0 bits (79), Expect = 0.24, Method: Compositional matrix adjust.
Identities = 20/64 (31%), Positives = 33/64 (51%)
Frame = -1
Query: 138 HKNFRTREGICLCLIATLNASGAQTLTLSKIVPHICNLLGDPNSQVRDAAINSLVEIYRH 197
H N + ICL + L + + LT+SK++ IC++L DPN D + + IY+
Sbjct: 313 HPNINSNGSICLDI---LRSQWSPALTISKVLLSICSMLTDPNPD--DPLVPEIARIYKT 149
Query: 198 VGER 201
E+
Sbjct: 148 DREK 137
>20120
Length = 1816
Score = 35.0 bits (79), Expect = 0.25, Method: Compositional matrix adjust.
Identities = 33/117 (28%), Positives = 47/117 (40%), Gaps = 20/117 (17%)
Frame = +3
Query: 108 REQDQTLLLKIMDQAANPQYVWDRMLGGFKHKNFRTREGICLC----------------- 150
R DQ+ L + A V D+ L + K +R E ICLC
Sbjct: 549 RYTDQSHLRTLYTLAEQHVQVSDKAL---QKKAYRILEEICLCESEACREFLMSNLTEIQ 719
Query: 151 --LIATLNASGAQTLTLS-KIVPHICNLLGDPNSQVRDAAINSLVEIYRHVGERVRA 204
L+ +L+AS T + + IC L PN+ A + + R VGE+VRA
Sbjct: 720 QLLLGSLSASAPNTRNPRLRCLTCICQQLTQPNTAFIQAVVPEAIMCTRGVGEKVRA 890
>00036
Length = 1324
Score = 30.8 bits (68), Expect = 4.6, Method: Composition-based stats.
Identities = 14/29 (48%), Positives = 18/29 (62%)
Frame = +3
Query: 64 YKVVLLGMDILSALVTRLQDRFKAQIGTV 92
YK V+ +DI +TRL D FK +GTV
Sbjct: 1185 YKQVMFHLDIFHCGITRLTDYFKFPMGTV 1271
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000308450 | hsapiens_gene_ensembl | Cell division
cycle protein 20 homolog (p55CDC).
[Source:Uniprot/SWISSPROT;Acc:Q12834]
(499 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
14500 177 2e-67
29912 209 2e-54
34005 157 5e-42
14884 112 3e-25
03387 62 7e-10
19949 57 2e-08
02147 57 2e-08
13335 55 6e-08
19498 54 2e-07
12574 54 2e-07
17266 52 5e-07
30256 51 8e-07
17598 50 2e-06
00561 49 4e-06
01327 48 1e-05
03156 47 1e-05
12806 47 2e-05
16105 46 4e-05
01768 46 4e-05
01805 45 1e-04
27465 43 2e-04
15780 42 6e-04
13278 42 7e-04
19140 39 0.004
10264 39 0.005
01598 39 0.005
11493 39 0.005
31474 39 0.006
01249 39 0.007
02960 38 0.009
17602 38 0.011
03044 37 0.014
15337 37 0.015
12960 37 0.018
14555 37 0.018
12140 37 0.021
37142 37 0.023
10162 36 0.042
18981 35 0.051
38177 35 0.064
21921 35 0.071
26107 35 0.082
03395 35 0.092
31864 35 0.099
27270 34 0.12
07665 34 0.15
02090 34 0.16
30176 33 0.27
07542 33 0.37
15972 32 0.57
31054 32 0.60
19863 32 0.86
35607 30 1.5
22113 30 1.5
34511 30 2.1
20172 30 2.2
12841 30 2.4
15118 30 2.7
12409 30 2.8
01707 29 3.5
36111 29 4.0
01462 29 4.5
21105 29 5.6
31384 28 7.0
27475 28 9.6
30295 28 9.7
>14500
Length = 1238
Score = 177 bits (449), Expect(2) = 2e-67, Method: Compositional matrix adjust.
Identities = 78/114 (68%), Positives = 95/114 (83%)
Frame = +3
Query: 363 WCPWQSNVLATGGGTSDRHIRIWNVCSGACLSAVDAHSQVCSILWSPHYKELISGHGFAQ 422
WCPWQ ++LA+GGGT+DRHI WN +G LS+VD SQVC++LWS ++ELIS HGFAQ
Sbjct: 225 WCPWQPSLLASGGGTADRHIHFWNCNTGTNLSSVDTKSQVCALLWSKEHRELISSHGFAQ 404
Query: 423 NQLVIWKYPTMAKVAELKGHTSRVLSLTMSPDGATVASAAADETLRLWRCFELD 476
NQL+IWKYP M++VAEL GHT+RVL + MSPDG TV SAAADETLRLW+CF +D
Sbjct: 405 NQLIIWKYPAMSRVAELTGHTARVLHMAMSPDGETVVSAAADETLRLWKCFTVD 566
Score = 97.8 bits (242), Expect(2) = 2e-67, Method: Compositional matrix adjust.
Identities = 47/68 (69%), Positives = 55/68 (80%), Gaps = 1/68 (1%)
Frame = +2
Query: 296 RVAEHHVATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPS-APGEGGWVPLQTFTQH 354
RVA+HHV TLSGHSQEVCGLRW+PDG++LASG NDNL+ VWP+ G PL TF+QH
Sbjct: 20 RVADHHVGTLSGHSQEVCGLRWSPDGKYLASGANDNLLCVWPAQVTGGNSTQPLHTFSQH 199
Query: 355 QGAVKAVA 362
Q AVKA+A
Sbjct: 200 QAAVKALA 223
Score = 33.9 bits (76), Expect = 0.15, Method: Compositional matrix adjust.
Identities = 16/35 (45%), Positives = 19/35 (54%)
Frame = +2
Query: 436 VAELKGHTSRVLSLTMSPDGATVASAAADETLRLW 470
V L GH+ V L SPDG +AS A D L +W
Sbjct: 38 VGTLSGHSQEVCGLRWSPDGKYLASGANDNLLCVW 142
Score = 28.9 bits (63), Expect = 4.6, Method: Compositional matrix adjust.
Identities = 12/35 (34%), Positives = 19/35 (54%)
Frame = +3
Query: 302 VATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVW 336
VA L+GH+ V + +PDG + S D + +W
Sbjct: 444 VAELTGHTARVLHMAMSPDGETVVSAAADETLRLW 548
>29912
Length = 510
Score = 209 bits (532), Expect = 2e-54, Method: Compositional matrix adjust.
Identities = 100/153 (65%), Positives = 119/153 (77%), Gaps = 1/153 (0%)
Frame = +3
Query: 225 PGEYISSVAWIKEGNYLAVGTSSAEVQLWDVQQQKRLRNMTSHSARVGSLSWNSYILXXX 284
P EYI +V+WIKEGNYLA+GTS+ EVQ+WDV QQK+LR M H+ARVGSLSWNS+I+
Sbjct: 6 PEEYIGAVSWIKEGNYLALGTSTGEVQVWDVTQQKKLRTMAGHAARVGSLSWNSFIVSSG 185
Query: 285 XXXXXXXXXDVRVAEHHVATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPS-APGEG 343
DVRVA+HHV TLSGHSQEVCGLRW+PDG++LASG NDNL+ VWP+ G
Sbjct: 186 SRSGNIHHHDVRVADHHVGTLSGHSQEVCGLRWSPDGKYLASGANDNLLCVWPAQVTGGN 365
Query: 344 GWVPLQTFTQHQGAVKAVAWCPWQSNVLATGGG 376
PL TF+QHQ AVKA+AWCPWQ + LA+GGG
Sbjct: 366 STQPLHTFSQHQAAVKALAWCPWQPSXLASGGG 464
Score = 38.5 bits (88), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 35/114 (30%), Positives = 51/114 (44%), Gaps = 1/114 (0%)
Frame = +3
Query: 358 VKAVAWCPWQSNVLATGGGTSDRHIRIWNVCSGACLSAVDAHS-QVCSILWSPHYKELIS 416
+ AV+W + N LA G TS +++W+V L + H+ +V S+ W+ S
Sbjct: 18 IGAVSWIK-EGNYLALG--TSTGEVQVWDVTQQKKLRTMAGHAARVGSLSWNSFIVSSGS 188
Query: 417 GHGFAQNQLVIWKYPTMAKVAELKGHTSRVLSLTMSPDGATVASAAADETLRLW 470
G + V V L GH+ V L SPDG +AS A D L +W
Sbjct: 189 RSGNIHHHDV---RVADHHVGTLSGHSQEVCGLRWSPDGKYLASGANDNLLCVW 341
>34005
Length = 456
Score = 157 bits (398), Expect(2) = 5e-42, Method: Compositional matrix adjust.
Identities = 73/115 (63%), Positives = 85/115 (73%)
Frame = +1
Query: 310 QEVCGLRWAPDGRHLASGGNDNLVNVWPSAPGEGGWVPLQTFTQHQGAVKAVAWCPWQSN 369
QEVCGL W+PD LASG NDN VN+W S G PL T T HQ AVKAVAWCPWQ+
Sbjct: 115 QEVCGLSWSPDATFLASGSNDNSVNIWDSTLGMDV-PPLHTLTSHQAAVKAVAWCPWQTR 291
Query: 370 VLATGGGTSDRHIRIWNVCSGACLSAVDAHSQVCSILWSPHYKELISGHGFAQNQ 424
+LATGGGT+DRHIR WN +GAC+ AVD SQVCS+LW ++EL+SGHG+ NQ
Sbjct: 292 MLATGGGTNDRHIRFWNTNTGACVKAVDTQSQVCSVLWCKEHRELVSGHGYVMNQ 456
Score = 32.0 bits (71), Expect(2) = 5e-42, Method: Compositional matrix adjust.
Identities = 16/36 (44%), Positives = 19/36 (52%)
Frame = +3
Query: 274 LSWNSYILXXXXXXXXXXXXDVRVAEHHVATLSGHS 309
L+WNS+IL DVRVA H V LS H+
Sbjct: 6 LAWNSHILSSGSRSGNIHHHDVRVARHKVGLLSTHT 113
Score = 34.3 bits (77), Expect = 0.11, Method: Compositional matrix adjust.
Identities = 30/131 (22%), Positives = 50/131 (38%), Gaps = 7/131 (5%)
Frame = +1
Query: 204 NSVYLWSASSGDILQLLQMEQPGEYISSVAWIKEGNYLAVGTSSAEVQLWDVQQQKR--- 260
+ Y W A+ L E + ++W + +LA G++ V +WD
Sbjct: 61 TTTYAWRATRWGFCPLTPQE-----VCGLSWSPDATFLASGSNDNSVNIWDSTLGMDVPP 225
Query: 261 LRNMTSHSARVGSLSWNSYILXXXXXXXXXXXXDVRVAEHH----VATLSGHSQEVCGLR 316
L +TSH A V +++W + +R + V + SQ VC +
Sbjct: 226 LHTLTSHQAAVKAVAWCPWQTRMLATGGGTNDRHIRFWNTNTGACVKAVDTQSQ-VCSVL 402
Query: 317 WAPDGRHLASG 327
W + R L SG
Sbjct: 403 WCKEHRELVSG 435
>14884
Length = 632
Score = 112 bits (281), Expect = 3e-25, Method: Compositional matrix adjust.
Identities = 75/215 (34%), Positives = 106/215 (49%), Gaps = 12/215 (5%)
Frame = -1
Query: 44 RAANRSHSAGRTPGRTPGKSSSKVQTTPSKPGGDRYIPHRSAAQMEVASFLLSKENQPEN 103
RA H AG+TP R K+ TP K DR+IP+R +++ F L + E
Sbjct: 599 RATPGKHVAGKTPNR-------KLAVTPGK-QQDRFIPNRMTTDQDMSHFALMHHHSKEE 444
Query: 104 S-----------QTPTKKEHQKAWALNLNGFDVEEAK-ILRLSGKPQNAPEGYQNRLKVL 151
T +++ +A N +G + K I + +P N L VL
Sbjct: 443 EEEEAGMTTHAGNTLYQQQLSEAMLHNQHGAKILSFKNICSVQSQPSN--------LSVL 288
Query: 152 YSQKATPGSSRKTCRYIPSLPDRILDAPEIRNDYYLNLVDWSSGNVLAVALDNSVYLWSA 211
YS P + R+IPS P+ +LDAP + +DYYL+ +DWSS N +A AL VYLW A
Sbjct: 287 YSTGKVPTTKSSNVRHIPSRPEHVLDAPVVLDDYYLHTIDWSSTNTVAAALGPEVYLWHA 108
Query: 212 SSGDILQLLQMEQPGEYISSVAWIKEGNYLAVGTS 246
I QL+++ +YISSV+WI +G L VG S
Sbjct: 107 RDATITQLMRVAD-SDYISSVSWISDGTVLGVGMS 6
>03387
Length = 1891
Score = 61.6 bits (148), Expect = 7e-10, Method: Compositional matrix adjust.
Identities = 50/175 (28%), Positives = 74/175 (42%), Gaps = 9/175 (5%)
Frame = +1
Query: 305 LSGHSQEVCGLRWAPD-GRHLASGGNDNLVNVWP--SAPGEGGWVPLQT-FTQHQGAVKA 360
L GH +E GL W P+ HL S +D+ + +W S E V T FT H V+
Sbjct: 349 LKGHQKEGYGLSWNPNLNGHLLSASDDHTICLWDINSTQRESRVVDAHTIFTGHTSVVED 528
Query: 361 VAWCPWQSNVLATGGGTSDRHIRIWNVCSGACLS---AVDAHSQVCSILWSPHYKELISG 417
VAW ++ G D+ + IW+ S VDAH+ + L Y E I
Sbjct: 529 VAWHLLHESLF--GSVADDQKLMIWDTRSNTTSKPSHVVDAHTAEVNCLSFNPYSEFILA 702
Query: 418 HGFAQNQLVIWKYPTMA-KVAELKGHTSRVLSLTMSPDGATV-ASAAADETLRLW 470
G A + +W + K+ + H + + SP T+ AS+ D L +W
Sbjct: 703 TGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLHVW 867
>19949
Length = 903
Score = 57.0 bits (136), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 35/117 (29%), Positives = 58/117 (49%), Gaps = 1/117 (0%)
Frame = +2
Query: 302 VATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPGEGGWVPLQTFTQHQGAVKAV 361
+ T GH+ VC LR++PDGR +AS D LV +W G+ L H+ AV +
Sbjct: 98 IYTYKGHTGCVCCLRFSPDGRWIASASEDGLVKLWDLTAGK----LLTDLKLHRDAVNTI 265
Query: 362 AWCPWQSNVLATGGGTSDRHIRIWNVCSGACLSAVDAHSQ-VCSILWSPHYKELISG 417
+ P + G++DR ++ W++ + +S + + + SIL+ P L SG
Sbjct: 266 EFHPHE---FLLASGSADRTVKFWDLETFQLISTTEPEANSIRSILFHPDGVCLYSG 427
Score = 36.2 bits (82), Expect = 0.030, Method: Compositional matrix adjust.
Identities = 18/52 (34%), Positives = 25/52 (48%)
Frame = +2
Query: 419 GFAQNQLVIWKYPTMAKVAELKGHTSRVLSLTMSPDGATVASAAADETLRLW 470
G + +W + KGHT V L SPDG +ASA+ D ++LW
Sbjct: 47 GSMDCNVKLWDIRRKGCIYTYKGHTGCVCCLRFSPDGRWIASASEDGLVKLW 202
>02147
Length = 1547
Score = 56.6 bits (135), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 49/243 (20%), Positives = 95/243 (39%), Gaps = 6/243 (2%)
Frame = +2
Query: 236 KEGNYLAVGTSSAEVQLWDVQQQKRLRNMT-SHSARVGSLSWNSYILXXXXXXXXXXXXD 294
+E A G + ++WD ++ + L+ + H + S + L D
Sbjct: 203 REATRAATGAADFSAKIWDAEKGEELQTFSHKHIVKSVDFSHDGTALLTGSNEKLLKVFD 382
Query: 295 VRVAEHHVATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPGEGGWVPLQTFTQH 354
+ + + +GH+ + G + DG+ + S +D V +W L+T +
Sbjct: 383 LVNTDAEPKSFAGHTSNIKGALFLSDGKRIISASDDKTVRLWS----------LETCQEV 532
Query: 355 QGAV-----KAVAWCPWQSNVLATGGGTSDRHIRIWNVCSGACLSAVDAHSQVCSILWSP 409
Q ++ P ++ ++ T ++I + + + +A + + S S
Sbjct: 533 QQLTFDTPPTSLTLSPDKNTIIVT----HSQNIAFYQADTLREMKKFEAEAPISSA--SL 694
Query: 410 HYKELISGHGFAQNQLVIWKYPTMAKVAELKGHTSRVLSLTMSPDGATVASAAADETLRL 469
H E G ++ + Y T ++ KGH V + SPDG AS + D TLRL
Sbjct: 695 HQSERFFVAGGEDFKMYKFDYETGKEIESFKGHFGPVHCVRFSPDGELYASGSEDGTLRL 874
Query: 470 WRC 472
W+
Sbjct: 875 WQT 883
Score = 39.7 bits (91), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 46/182 (25%), Positives = 80/182 (43%), Gaps = 9/182 (4%)
Frame = +2
Query: 302 VATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPGEGGWVPLQTFTQHQGAVKAV 361
+ T GH V G + A+G D +W + GE LQTF+ H+ VK+V
Sbjct: 152 IGTFEGHKGAVWGATLNREATRAATGAADFSAKIWDAEKGE----ELQTFS-HKHIVKSV 316
Query: 362 AWCPWQSNVLATGGGTSDRHIRIWN-VCSGACLSAVDAH-SQVCSILWSPHYKELISGHG 419
+ + +L G++++ +++++ V + A + H S + L+ K +IS
Sbjct: 317 DFSHDGTALLT---GSNEKLLKVFDLVNTDAEPKSFAGHTSNIKGALFLSDGKRIISASD 487
Query: 420 FAQNQLVIWKYPTMAKVAELKGHTSRVLSLTMSPDGATVASAAAD-------ETLRLWRC 472
+ +W T +V +L T SLT+SPD T+ + +TLR +
Sbjct: 488 --DKTVRLWSLETCQEVQQLTFDTPPT-SLTLSPDKNTIIVTHSQNIAFYQADTLREMKK 658
Query: 473 FE 474
FE
Sbjct: 659 FE 664
Score = 37.0 bits (84), Expect = 0.016, Method: Compositional matrix adjust.
Identities = 34/149 (22%), Positives = 58/149 (38%), Gaps = 4/149 (2%)
Frame = +2
Query: 197 VLAVALDNSVYLWSASSGDILQLLQMEQPGEYISSVAWIKEGNYLAVGTSSAEVQLWDVQ 256
+++ + D +V LWS + +Q L + P +S+ + N + V T S + +
Sbjct: 470 IISASDDKTVRLWSLETCQEVQQLTFDTPP---TSLTLSPDKNTIIV-THSQNIAFY--- 628
Query: 257 QQKRLRNMTSHSARV----GSLSWNSYILXXXXXXXXXXXXDVRVAEHHVATLSGHSQEV 312
Q LR M A SL + D + + + GH V
Sbjct: 629 QADTLREMKKFEAEAPISSASLHQSERFFVAGGEDFKMYKFDYETGKE-IESFKGHFGPV 805
Query: 313 CGLRWAPDGRHLASGGNDNLVNVWPSAPG 341
+R++PDG ASG D + +W + G
Sbjct: 806 HCVRFSPDGELYASGSEDGTLRLWQTTIG 892
>13335
Length = 863
Score = 55.1 bits (131), Expect = 6e-08, Method: Compositional matrix adjust.
Identities = 47/184 (25%), Positives = 82/184 (44%), Gaps = 22/184 (11%)
Frame = +1
Query: 309 SQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPGEGGWVPLQTFTQHQGAVKAVAWCPWQS 368
S VC +++P HL SG +D+ + +W A + ++++ H+ +V A+A+ P
Sbjct: 67 SIRVC--KFSPSSSHLVSGSDDDTICMWEVATQK----LVRSYVGHEDSVMALAYSP-NG 225
Query: 369 NVLATGGGTSDRHIRIWNVCSGACLSA---VDAHSQ-VCSILWSPHYK----------EL 414
+ L +G D + +W+ G C VDAH V +SP + L
Sbjct: 226 HYLVSGSPNGD--LYVWDASFGHCRHLTLRVDAHDLGVTCCEFSPTFGTACAENSSTCNL 399
Query: 415 ISGHGFAQNQLVIWKYPTMAKVAE--------LKGHTSRVLSLTMSPDGATVASAAADET 466
+ G N + +W + E L GH+ V++ SP A +AS + D++
Sbjct: 400 LLATGGKDNLIKLWTFSAQVGSPEVTLQCRDILSGHSDLVMACAFSPSSALLASGSFDKS 579
Query: 467 LRLW 470
+RLW
Sbjct: 580 VRLW 591
Score = 42.0 bits (97), Expect = 6e-04, Method: Compositional matrix adjust.
Identities = 44/191 (23%), Positives = 75/191 (39%), Gaps = 21/191 (10%)
Frame = +1
Query: 302 VATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPGEGGWVPLQTFTQHQGAVKAV 361
V + GH V L ++P+G +L SG + + VW ++ G + L+ H V
Sbjct: 166 VRSYVGHEDSVMALAYSPNGHYLVSGSPNGDLYVWDASFGHCRHLTLRV-DAHDLGVTCC 342
Query: 362 AWCPWQSN-----------VLATGGGTSDRHIRIWNVCSGA--------CLSAVDAHSQ- 401
+ P +LATGG D I++W + C + HS
Sbjct: 343 EFSPTFGTACAENSSTCNLLLATGG--KDNLIKLWTFSAQVGSPEVTLQCRDILSGHSDL 516
Query: 402 VCSILWSPHYKELISGHGFAQNQLVIWKYPTMAKVAELKG-HTSRVLSLTMSPDGATVAS 460
V + +SP L SG + +W + ++ H+ V S DG +AS
Sbjct: 517 VMACAFSPSSALLASGS--FDKSVRLWDSVKGVALFSIEACHSRFVTCCAFSIDGTLLAS 690
Query: 461 AAADETLRLWR 471
+ D +++W+
Sbjct: 691 GSMDRIIKIWK 723
Score = 40.0 bits (92), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 25/83 (30%), Positives = 36/83 (43%)
Frame = +1
Query: 305 LSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPGEGGWVPLQTFTQHQGAVKAVAWC 364
LSGHS V ++P LASG D V +W S G + F+ + V C
Sbjct: 496 LSGHSDLVMACAFSPSSALLASGSFDKSVRLWDSVKG------VALFSIEACHSRFVTCC 657
Query: 365 PWQSNVLATGGGTSDRHIRIWNV 387
+ + G+ DR I+IW +
Sbjct: 658 AFSIDGTLLASGSMDRIIKIWKL 726
Score = 40.0 bits (92), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 47/218 (21%), Positives = 95/218 (43%), Gaps = 9/218 (4%)
Frame = +1
Query: 193 SSGNVLAVALDNSVYLWSASSGDILQLLQMEQPGEYISSVAWIKEGNYLAVGTSSAEVQL 252
SS ++++ + D+++ +W ++ +++ + + + ++A+ G+YL G+ + ++ +
Sbjct: 94 SSSHLVSGSDDDTICMWEVATQKLVRSYVGHE--DSVMALAYSPNGHYLVSGSPNGDLYV 267
Query: 253 WDVQQQKRLRNMTSHSARVGSLSWNSYILXXXXXXXXXXXXDVRVAEHHVATLSGHSQEV 312
WD R++T +RV H +
Sbjct: 268 WD-ASFGHCRHLT-----------------------------LRVDAHDLGVTCCEFSPT 357
Query: 313 CGLRWAPDGRH----LASGGNDNLVNVWPSAPGEGG-WVPLQT---FTQHQGAVKAVAWC 364
G A + LA+GG DNL+ +W + G V LQ + H V A A+
Sbjct: 358 FGTACAENSSTCNLLLATGGKDNLIKLWTFSAQVGSPEVTLQCRDILSGHSDLVMACAFS 537
Query: 365 PWQSNVLATGGGTSDRHIRIWNVCSGACLSAVDA-HSQ 401
P S +LA+ G+ D+ +R+W+ G L +++A HS+
Sbjct: 538 P-SSALLAS--GSFDKSVRLWDSVKGVALFSIEACHSR 642
>19498
Length = 903
Score = 53.5 bits (127), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 47/184 (25%), Positives = 72/184 (39%), Gaps = 14/184 (7%)
Frame = -1
Query: 302 VATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPGEGG-------------WVPL 348
+ + H V +RW+ +G+ LASGG+D L+ +W + G G W +
Sbjct: 807 LCQMDSHLGCVNCVRWSENGKFLASGGDDKLIMIWQISRGFGSGKSFGSNVTILEHWRSV 628
Query: 349 QTFTQHQGAVKAVAWCPWQSNVLATGGGTSDRHIRIWNVCSGACLSAVDAHSQVCSILWS 408
T H G V +AW P Q LA+ CS+
Sbjct: 627 ATLRGHAGDVLDLAWSP-QDLWLAS-----------------------------CSV--- 547
Query: 409 PHYKELISGHGFAQNQLVIWKYPTMA-KVAELKGHTSRVLSLTMSPDGATVASAAADETL 467
N +V+W + +VA ++GH V +T P G +AS + D+TL
Sbjct: 546 -------------DNTIVVWNALKFSEQVAVIRGHAGMVKGVTWDPVGRYLASQSDDKTL 406
Query: 468 RLWR 471
R+WR
Sbjct: 405 RVWR 394
Score = 43.5 bits (101), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 31/141 (21%), Positives = 59/141 (41%), Gaps = 20/141 (14%)
Frame = -1
Query: 219 LLQMEQPGEYISSVAWIKEGNYLAVGTSSAEVQLWDV-----------------QQQKRL 261
L QM+ ++ V W + G +LA G + +W + + + +
Sbjct: 807 LCQMDSHLGCVNCVRWSENGKFLASGGDDKLIMIWQISRGFGSGKSFGSNVTILEHWRSV 628
Query: 262 RNMTSHSARVGSLSW---NSYILXXXXXXXXXXXXDVRVAEHHVATLSGHSQEVCGLRWA 318
+ H+ V L+W + ++ ++ +E VA + GH+ V G+ W
Sbjct: 627 ATLRGHAGDVLDLAWSPQDLWLASCSVDNTIVVWNALKFSEQ-VAVIRGHAGMVKGVTWD 451
Query: 319 PDGRHLASGGNDNLVNVWPSA 339
P GR+LAS +D + VW ++
Sbjct: 450 PVGRYLASQSDDKTLRVWRTS 388
Score = 28.5 bits (62), Expect = 5.8, Method: Compositional matrix adjust.
Identities = 26/93 (27%), Positives = 35/93 (37%), Gaps = 14/93 (15%)
Frame = -1
Query: 307 GHSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAP--GEGGWVPLQTFTQHQGAVKAVAWC 364
G + V L W+PDG H+ S N N P+A GW F H+ A+ V +
Sbjct: 342 GGTTHVLRLNWSPDGNHVVSAHAMN--NAXPTAQIIERNGWGTSLDFVGHRKAITVVRFN 169
Query: 365 P------------WQSNVLATGGGTSDRHIRIW 385
P Q G+ DR + IW
Sbjct: 168 PKILSKQIKKSAEKQQQYSCCAIGSKDRSLSIW 70
>12574
Length = 521
Score = 53.5 bits (127), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 31/115 (26%), Positives = 60/115 (52%), Gaps = 1/115 (0%)
Frame = +3
Query: 304 TLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPGEGGWVPLQTFTQHQGAVKAVAW 363
TL+GH++ + ++++P+G LAS D L+ +W + G+ +T H+ + VAW
Sbjct: 171 TLAGHTKALSAVKFSPNGDWLASSSADKLIKIWGAYDGKFE----KTIAGHKLGLSDVAW 338
Query: 364 CPWQSNVLATGGGTSDRHIRIWNVCSGACLSAVDAHSQ-VCSILWSPHYKELISG 417
S +L + + D+ ++IW +G C+ + HS V ++P ++SG
Sbjct: 339 SS-DSKLLCS--ASDDKTLKIWEFSTGKCMKTLKGHSNYVFCCNFNPQSNLIVSG 494
Score = 38.1 bits (87), Expect = 0.009, Method: Compositional matrix adjust.
Identities = 30/114 (26%), Positives = 49/114 (42%), Gaps = 1/114 (0%)
Frame = +3
Query: 350 TFTQHQGAVKAVAWCPWQSNVLATGGGTSDRHIRIWNVCSGACLSAVDAHS-QVCSILWS 408
T H A+ AV + P + LA+ ++D+ I+IW G + H + + WS
Sbjct: 171 TLAGHTKALSAVKFSP-NGDWLASS--SADKLIKIWGAYDGKFEKTIAGHKLGLSDVAWS 341
Query: 409 PHYKELISGHGFAQNQLVIWKYPTMAKVAELKGHTSRVLSLTMSPDGATVASAA 462
K L S L IW++ T + LKGH++ V +P + S +
Sbjct: 342 SDSKLLCSASD--DKTLKIWEFSTGKCMKTLKGHSNYVFCCNFNPQSNLIVSGS 497
Score = 33.1 bits (74), Expect = 0.27, Method: Compositional matrix adjust.
Identities = 14/44 (31%), Positives = 27/44 (61%)
Frame = +3
Query: 431 PTMAKVAELKGHTSRVLSLTMSPDGATVASAAADETLRLWRCFE 474
PT L GHT + ++ SP+G +AS++AD+ +++W ++
Sbjct: 150 PTYTLKFTLAGHTKALSAVKFSPNGDWLASSSADKLIKIWGAYD 281
>17266
Length = 480
Score = 52.0 bits (123), Expect = 5e-07, Method: Composition-based stats.
Identities = 46/168 (27%), Positives = 74/168 (44%), Gaps = 8/168 (4%)
Frame = -1
Query: 308 HSQEVCG----LRWAPDGRHLASGGNDNLVNVWPSAPGEGGWVPLQTFTQHQGAVKAVAW 363
HSQ G L APD R SG D +W G + QTF+ H+ + A+ +
Sbjct: 474 HSQATLGT**VLSLAPDMRTFVSGACDASAKLWDVRDG----MCKQTFSGHESDINAITY 307
Query: 364 CPWQSNVLATGGGTSDRHIRIWNVCSGACLSAVDAHSQVC---SILWSPHYKELISGHG- 419
P N A G+ D R++++ + + + +C S+ +S + L+ G+
Sbjct: 306 FP---NGHAFATGSDDATCRLFDIRADQEIGMYSHDNIICGITSVAFSKSGRLLLGGYDD 136
Query: 420 FAQNQLVIWKYPTMAKVAELKGHTSRVLSLTMSPDGATVASAAADETL 467
F N IW + L GH +RV L ++ DG+ VA+ + D L
Sbjct: 135 FNCN---IWDVLKQERTGVLAGHDNRVSCLGVTEDGSAVATGSWDSFL 1
Score = 34.7 bits (78), Expect = 0.10, Method: Composition-based stats.
Identities = 20/64 (31%), Positives = 29/64 (45%), Gaps = 12/64 (18%)
Frame = -1
Query: 229 ISSVAWIKEGNYLAVGTSSAEVQLWDVQQQKRLRNMTSHSARVGSL------------SW 276
I+SVA+ K G L G +WDV +Q+R + H RV L SW
Sbjct: 192 ITSVAFSKSGRLLLGGYDDFNCNIWDVLKQERTGVLAGHDNRVSCLGVTEDGSAVATGSW 13
Query: 277 NSYI 280
+S++
Sbjct: 12 DSFL 1
>30256
Length = 961
Score = 51.2 bits (121), Expect = 8e-07, Method: Compositional matrix adjust.
Identities = 51/179 (28%), Positives = 83/179 (46%), Gaps = 5/179 (2%)
Frame = +3
Query: 302 VATLSGHSQEVCGLRWAPD--GRHLASGGNDNLVNVWPSAPGEGGWVPLQTFTQHQGAVK 359
+ L GH+ V W+ G + SG D + VW + G V T H V+
Sbjct: 21 IKNLIGHTGGV----WSSQMTGNTVISGSTDRSLKVWNADTG----VCTHTLYGHSSTVR 176
Query: 360 AVAWCPWQSNVLATGGGTSDRHIRIWNVCSGACLSAVDAHSQVCSILWSPHYKELISGHG 419
++ V++ G+ D +R+W++ SG CL+ + H + K ++SG
Sbjct: 177 CLSLSG--KKVVS---GSRDATLRVWDIESGHCLNVLLGHMAAVRCV-QYDGKRVVSG-- 332
Query: 420 FAQNQLV-IWKYPTMAKVAELKGHTSRVLSLTMSPDGATVASAAADETLRLW--RCFEL 475
A + V +W T + + L+GHT+RV SL DG V S + D ++R+W RC +L
Sbjct: 333 -AXDYTVRVWDPDTASCLHTLQGHTNRVYSLQF--DGVYVVSGSLDTSIRVWDVRCGKL 500
Score = 47.8 bits (112), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 51/209 (24%), Positives = 92/209 (44%), Gaps = 4/209 (1%)
Frame = +3
Query: 192 WSS---GN-VLAVALDNSVYLWSASSGDILQLLQMEQPGEYISSVAWIKEGNYLAVGTSS 247
WSS GN V++ + D S+ +W+A +G L S++ G + G+
Sbjct: 54 WSSQMTGNTVISGSTDRSLKVWNADTGVCTHTLYGHSSTVRCLSLS----GKKVVSGSRD 221
Query: 248 AEVQLWDVQQQKRLRNMTSHSARVGSLSWNSYILXXXXXXXXXXXXDVRVAEHHVATLSG 307
A +++WD++ L + H A V + ++ + D A + TL G
Sbjct: 222 ATLRVWDIESGHCLNVLLGHMAAVRCVQYDGKRVVSGAXDYTVRVWDPDTASC-LHTLQG 398
Query: 308 HSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPGEGGWVPLQTFTQHQGAVKAVAWCPWQ 367
H+ V L++ DG ++ SG D + VW G+ + T HQ + +
Sbjct: 399 HTNRVYSLQF--DGVYVVSGSLDTSIRVWDVRCGK----LVHTLMGHQSLTSGL---ELK 551
Query: 368 SNVLATGGGTSDRHIRIWNVCSGACLSAV 396
N+L +G +D +++W+V +G CL +
Sbjct: 552 DNLLVSG--NADSTVKVWDVHTGKCLQTL 632
>17598
Length = 875
Score = 50.1 bits (118), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 42/170 (24%), Positives = 72/170 (42%), Gaps = 3/170 (1%)
Frame = +1
Query: 304 TLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPGEGGWVPLQTFTQHQGAVKAVAW 363
TL GHS V + + D R++ S D + +W G + F H AVA+
Sbjct: 106 TLQGHSHFVSDVSLSADSRYVLSSSWDATLRLWDIKKGN----TTRRFISHTRDALAVAF 273
Query: 364 CPWQSNVLATGGGTSDRHIRIWNVCSGACLSAVDAHSQ---VCSILWSPHYKELISGHGF 420
P + +A+GG D+ ++IWN G C VDA+S V + + K +
Sbjct: 274 SP-DNRQIASGG--RDKALKIWNTV-GECKFTVDANSHQDWVTCVKFHQDAKSPLVVSAS 441
Query: 421 AQNQLVIWKYPTMAKVAELKGHTSRVLSLTMSPDGATVASAAADETLRLW 470
+ +W TM GH +++ ++ ++ +AS + D + W
Sbjct: 442 MDKTIKVWDNQTMTLKHTFVGHKTQINAIDLALKTYYLASGSKDGIVMTW 591
Score = 43.1 bits (100), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 45/220 (20%), Positives = 92/220 (41%), Gaps = 6/220 (2%)
Frame = +1
Query: 228 YISSVAWIKEGNYLAVGTSSAEVQLWDVQQQKRLRNMTSHSARVGSLSW---NSYILXXX 284
++S V+ + Y+ + A ++LWD+++ R SH+ ++++ N I
Sbjct: 127 FVSDVSLSADSRYVLSSSWDATLRLWDIKKGNTTRRFISHTRDALAVAFSPDNRQIASGG 306
Query: 285 XXXXXXXXXDVRVAEHHVATLSGHSQEVCGLRWAPDGRH--LASGGNDNLVNVWPSAPGE 342
V + V S H V +++ D + + S D + VW +
Sbjct: 307 RDKALKIWNTVGECKFTVDANS-HQDWVTCVKFHQDAKSPLVVSASMDKTIKVWDNQT-- 477
Query: 343 GGWVPLQ-TFTQHQGAVKAVAWCPWQSNVLATGGGTSDRHIRIWNVCSGACLSAVDAHSQ 401
+ L+ TF H+ + A+ ++ LA+ G+ D + WN+ +G L +D +
Sbjct: 478 ---MTLKHTFVGHKTQINAID-LALKTYYLAS--GSKDGIVMTWNIQNGTFLGKIDCDCE 639
Query: 402 VCSILWSPHYKELISGHGFAQNQLVIWKYPTMAKVAELKG 441
V ++ +SP+ L G + IW P K+ +++
Sbjct: 640 VNAVKFSPNKYWLFVG---TSEGIQIWDLPNQKKIKDIRA 750
Score = 37.0 bits (84), Expect = 0.019, Method: Compositional matrix adjust.
Identities = 39/157 (24%), Positives = 67/157 (42%), Gaps = 10/157 (6%)
Frame = +1
Query: 324 LASGGNDNLVNVWPSAPGEGG-----W-VPLQTFTQHQGAVKAVAWCPWQSNVLATGGGT 377
L GG D L+ VW P + G W P +T H V V+ VL++ +
Sbjct: 10 LIXGGRDKLLIVWDLVPRKDGDEDETWGGPRRTLQGHSHFVSDVSLSADSRYVLSS---S 180
Query: 378 SDRHIRIWNVCSGACLSAVDAHSQ-VCSILWSPHYKELISGHGFAQNQLVIWKYPTMAKV 436
D +R+W++ G +H++ ++ +SP +++ SG L IW K
Sbjct: 181 WDATLRLWDIKKGNTTRRFISHTRDALAVAFSPDNRQIASGG--RDKALKIWNTVGECKF 354
Query: 437 -AELKGHTSRVLSLTMSPDGAT--VASAAADETLRLW 470
+ H V + D + V SA+ D+T+++W
Sbjct: 355 TVDANSHQDWVTCVKFHQDAKSPLVVSASMDKTIKVW 465
>00561
Length = 1003
Score = 40.8 bits (94), Expect(2) = 4e-06, Method: Compositional matrix adjust.
Identities = 45/198 (22%), Positives = 80/198 (40%), Gaps = 5/198 (2%)
Frame = -3
Query: 227 EYISSVAWIKEGNYLAVGTSSAEVQLWDVQQQKRLRNMTSHSARVGSLSW---NSYILXX 283
+IS V +GNY G+ ++LWD+ K R H+ V S+++ N I+
Sbjct: 863 HFISDVVLSSDGNYALSGSWDQTLRLWDLAAGKTTRRFEGHTKDVLSVAFSADNRQIVSG 684
Query: 284 XXXXXXXXXXDVRVAEHHVATLSGHSQEVCGLRWAPDGRH--LASGGNDNLVNVWPSAPG 341
+ + + GH+ V +R++P+ + + S G D V VW A
Sbjct: 683 SRDKTIKLWNTLAECKFTIQE-DGHTDWVSCVRFSPNHSNPIIVSCGWDRTVKVWNLANC 507
Query: 342 EGGWVPLQTFTQHQGAVKAVAWCPWQSNVLATGGGTSDRHIRIWNVCSGACLSAVDAHSQ 401
+ H G + V P L T GG D +W++ G L ++ +
Sbjct: 506 KLK----NNHHGHNGYLNTVTVSP--DGSLCTSGG-KDSKALLWDLNDGKNLYTLEHNDI 348
Query: 402 VCSILWSPHYKELISGHG 419
+ ++ +SP+ L +G
Sbjct: 347 INALCFSPNRYWLCVAYG 294
Score = 27.7 bits (60), Expect(2) = 4e-06, Method: Compositional matrix adjust.
Identities = 12/32 (37%), Positives = 19/32 (59%)
Frame = -2
Query: 440 KGHTSRVLSLTMSPDGATVASAAADETLRLWR 471
K + LSL S DG T+ + +D T+R+W+
Sbjct: 216 KAEQPQCLSLAWSTDGQTLFAGYSDNTIRVWQ 121
Score = 48.9 bits (115), Expect = 5e-06, Method: Compositional matrix adjust.
Identities = 43/170 (25%), Positives = 75/170 (44%), Gaps = 4/170 (2%)
Frame = -3
Query: 305 LSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPGEGGWVPLQTFTQHQGAVKAVAWC 364
L GHS + + + DG + SG D + +W A G+ + F H V +VA+
Sbjct: 878 LYGHSHFISDVVLSSDGNYALSGSWDQTLRLWDLAAGKT----TRRFEGHTKDVLSVAFS 711
Query: 365 PWQSNVLATGGGTSDRHIRIWNVCSGACLSAV--DAHSQ-VCSILWSP-HYKELISGHGF 420
+++ G+ D+ I++WN + C + D H+ V + +SP H +I G+
Sbjct: 710 ADNRQIVS---GSRDKTIKLWNTLA-ECKFTIQEDGHTDWVSCVRFSPNHSNPIIVSCGW 543
Query: 421 AQNQLVIWKYPTMAKVAELKGHTSRVLSLTMSPDGATVASAAADETLRLW 470
+ + +W GH + ++T+SPDG+ S D LW
Sbjct: 542 DRT-VKVWNLANCKLKNNHHGHNGYLNTVTVSPDGSLCTSGGKDSKALLW 396
Score = 30.4 bits (67), Expect = 1.9, Method: Compositional matrix adjust.
Identities = 18/56 (32%), Positives = 26/56 (46%), Gaps = 10/56 (17%)
Frame = -3
Query: 425 LVIWK----------YPTMAKVAELKGHTSRVLSLTMSPDGATVASAAADETLRLW 470
L++WK YP L GH+ + + +S DG S + D+TLRLW
Sbjct: 938 LIVWKLTRDEDTNYGYPQ----KRLYGHSHFISDVVLSSDGNYALSGSWDQTLRLW 783
>01327
Length = 2215
Score = 47.8 bits (112), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 43/186 (23%), Positives = 72/186 (38%), Gaps = 8/186 (4%)
Frame = +3
Query: 296 RVAEHHVATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPGEGGWVPLQTFTQHQ 355
R H + GH V + D L SG DN V +W G L+ Q
Sbjct: 252 RGNSHSIRDFIGHDMVVTAIHLNTDNTLLCSGSRDNTVRIWDVETG----ACLRQNNIPQ 419
Query: 356 GAVKAVAWCPWQSNVLATGGGTSDRHIRIWNVCSGACLSAVDAHSQV---CSILWSPHYK 412
V V W P ++ G D+ +RI++ + + + + C + +
Sbjct: 420 NLVTDVKWLPGSHLIIQAG---EDKEVRIYDSRTLGIVRSFTKKQYIQMSCDVTADGQFC 590
Query: 413 ELISGHGFAQN--QLVIWKYPTMAKVAELKGHTSRV---LSLTMSPDGATVASAAADETL 467
L +GF N + +W+ + E KGH + L L + D +A+A+ D ++
Sbjct: 591 -LTCSNGFGGNGCEATLWQLSDGSIQNEFKGHREAIEACLFLPSNQDMTLIATASRDCSV 767
Query: 468 RLWRCF 473
R+W F
Sbjct: 768 RVWNMF 785
Score = 29.3 bits (64), Expect = 4.3, Method: Compositional matrix adjust.
Identities = 15/74 (20%), Positives = 33/74 (44%), Gaps = 10/74 (13%)
Frame = +3
Query: 407 WSPHYKELIS-GHGFAQNQLV---------IWKYPTMAKVAELKGHTSRVLSLTMSPDGA 456
W+ H +E+ +G + N + +W+ + + GH V ++ ++ D
Sbjct: 153 WTGHDREITKVCYGASCNGMFSASRDKTIKMWQRGNSHSIRDFIGHDMVVTAIHLNTDNT 332
Query: 457 TVASAAADETLRLW 470
+ S + D T+R+W
Sbjct: 333 LLCSGSRDNTVRIW 374
>03156
Length = 1014
Score = 47.4 bits (111), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 42/186 (22%), Positives = 71/186 (38%), Gaps = 8/186 (4%)
Frame = +1
Query: 296 RVAEHHVATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPGEGGWVPLQTFTQHQ 355
R H + GH V + D L SG DN V +W G L+ Q
Sbjct: 142 RGNSHSIRDFIGHDMVVTAIHLNTDNTLLCSGSRDNTVRIWDVETG----ACLRQNNIPQ 309
Query: 356 GAVKAVAWCPWQSNVLATGGGTSDRHIRIWNVCSGACLSAVDAHSQV---CSILWSPHYK 412
V V W P ++ G D+ +RI++ + + + + C + +
Sbjct: 310 NLVTDVKWLPGSHLIIQAG---EDKEVRIYDSRTLGIVRSFTKKQYIQMSCDVTADGQFC 480
Query: 413 ELISGHGFAQN--QLVIWKYPTMAKVAELKGHTSRVLSLTMSP---DGATVASAAADETL 467
L +GF N + +W+ + E KGH + + P D +A+A+ D ++
Sbjct: 481 -LTCSNGFGGNGCEATLWQLSDGSIQNEFKGHREAIEACLFLPSNQDMTLIATASRDCSV 657
Query: 468 RLWRCF 473
R+W F
Sbjct: 658 RVWNMF 675
Score = 28.9 bits (63), Expect = 5.4, Method: Compositional matrix adjust.
Identities = 15/74 (20%), Positives = 33/74 (44%), Gaps = 10/74 (13%)
Frame = +1
Query: 407 WSPHYKELIS-GHGFAQNQLV---------IWKYPTMAKVAELKGHTSRVLSLTMSPDGA 456
W+ H +E+ +G + N + +W+ + + GH V ++ ++ D
Sbjct: 43 WTGHDREITKVCYGASCNGMFSASRDKTIKMWQRGNSHSIRDFIGHDMVVTAIHLNTDNT 222
Query: 457 TVASAAADETLRLW 470
+ S + D T+R+W
Sbjct: 223 LLCSGSRDNTVRIW 264
>12806
Length = 961
Score = 47.0 bits (110), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 45/157 (28%), Positives = 74/157 (47%), Gaps = 10/157 (6%)
Frame = +3
Query: 324 LASGGNDNLVNVWPSAPGEGG-----W-VPLQTFTQHQGAVKAVAWCPWQSNVLATGGGT 377
L SGG DN + VW P + G W VP +T T H + +A L++ +
Sbjct: 54 LISGGRDNNIIVWDL*PKKDGDEDQTWGVPRKTLTGHSHFISDLALSADSRFALSS---S 224
Query: 378 SDRHIRIWNVCSGACLSAVDAHSQ-VCSILWSPHYKELISGHGFAQNQLVIWKYPTMAK- 435
D +R+W++ G+ S H++ V ++ +SP +++ SG G +N L IW K
Sbjct: 225 WDATLRLWDIKKGSTTSRFINHTRDVLTVAFSPDNRQIASG-GRDKN-LKIWNIMGECKY 398
Query: 436 VAELKGHTSRVLSLTMSPDGAT--VASAAADETLRLW 470
+ HT V + D V SA+ D+T+++W
Sbjct: 399 TVDANAHTDWVTCVRFHQDTKNPIVVSASNDKTIKVW 509
Score = 45.1 bits (105), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 43/219 (19%), Positives = 92/219 (42%), Gaps = 5/219 (2%)
Frame = +3
Query: 228 YISSVAWIKEGNYLAVGTSSAEVQLWDVQQQKRLRNMTSHSARVGSLSW--NSYILXXXX 285
+IS +A + + + A ++LWD+++ +H+ V ++++ ++ +
Sbjct: 171 FISDLALSADSRFALSSSWDATLRLWDIKKGSTTSRFINHTRDVLTVAFSPDNRQIASGG 350
Query: 286 XXXXXXXXDVRVAEHHVATLSGHSQEVCGLRWAPDGRH--LASGGNDNLVNVWPSAPGEG 343
++ + + H+ V +R+ D ++ + S ND + VW +
Sbjct: 351 RDKNLKIWNIMGECKYTVDANAHTDWVTCVRFHQDTKNPIVVSASNDKTIKVWDNHT--- 521
Query: 344 GWVPLQTFTQHQGAVKAVAWCPWQSNVLATGGGTSDRHIRIWNVCSGACLSAVDAHSQVC 403
TF H+ + A+ +N L +G + D WNV G+ + +D Q+
Sbjct: 522 -MTLKNTFVGHKAQITAL---DMSTNYLVSG--SKDGIAMTWNVAEGSFVGKIDCDDQIN 683
Query: 404 SILWS-PHYKELISGHGFAQNQLVIWKYPTMAKVAELKG 441
+I ++ + K+ + QN + IW Y K+ ELK
Sbjct: 684 AIKFNIENNKKKVWLFIGTQNGIQIWDYSGEKKIKELKA 800
>16105
Length = 960
Score = 45.8 bits (107), Expect = 4e-05, Method: Compositional matrix adjust.
Identities = 27/124 (21%), Positives = 57/124 (45%), Gaps = 8/124 (6%)
Frame = -2
Query: 354 HQGAVKAVAWCPWQSNVLATGGGTSDRHIRIWNV--------CSGACLSAVDAHSQVCSI 405
H+GAV + WCP NV+A+ + D +++W + + + V + C I
Sbjct: 578 HKGAVLDIQWCPHNDNVIAS--ASDDCTVKVWQIPDSGLVTNLTDPVVDLVGHQKRCCLI 405
Query: 406 LWSPHYKELISGHGFAQNQLVIWKYPTMAKVAELKGHTSRVLSLTMSPDGATVASAAADE 465
+W P + ++ G A N+++ W T + E+ + ++ + +G+ + D+
Sbjct: 404 VWHPSAQNVLVSAG-ADNKILFWNVGTGEPMLEVD-VPDMIYCMSFNFNGSRLVCTCKDK 231
Query: 466 TLRL 469
LR+
Sbjct: 230 KLRI 219
Score = 40.8 bits (94), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 30/103 (29%), Positives = 44/103 (42%), Gaps = 5/103 (4%)
Frame = -2
Query: 305 LSGHSQEVCGLRWAPDGRH-LASGGNDNLVNVWPSAPGEGGWV----PLQTFTQHQGAVK 359
++GH V ++W P + +AS +D V VW P G P+ HQ
Sbjct: 587 VAGHKGAVLDIQWCPHNDNVIASASDDCTVKVW-QIPDSGLVTNLTDPVVDLVGHQKRCC 411
Query: 360 AVAWCPWQSNVLATGGGTSDRHIRIWNVCSGACLSAVDAHSQV 402
+ W P NVL + G +D I WNV +G + VD +
Sbjct: 410 LIVWHPSAQNVLVSAG--ADNKILFWNVGTGEPMLEVDVPDMI 288
Score = 30.4 bits (67), Expect = 1.5, Method: Compositional matrix adjust.
Identities = 15/42 (35%), Positives = 20/42 (47%), Gaps = 1/42 (2%)
Frame = -2
Query: 302 VATLSGHSQEVCGLRWAPDGRH-LASGGNDNLVNVWPSAPGE 342
V L GH + C + W P ++ L S G DN + W GE
Sbjct: 446 VVDLVGHQKRCCLIVWHPSAQNVLVSAGADNKILFWNVGTGE 321
>01768
Length = 1424
Score = 45.8 bits (107), Expect = 4e-05, Method: Compositional matrix adjust.
Identities = 28/83 (33%), Positives = 42/83 (50%), Gaps = 2/83 (2%)
Frame = +3
Query: 307 GHSQEVCGLRWAPDGRH-LASGGNDNLVNVWPSAPGEGGWVPLQ-TFTQHQGAVKAVAWC 364
HS+++ + W P +H LASGG+D ++ +W V Q +F H V ++ W
Sbjct: 972 AHSRDINVINWNPIEKHLLASGGDDGIIKIWDLRMFRNKPVSAQASFKLHSQPVTSLEWN 1151
Query: 365 PWQSNVLATGGGTSDRHIRIWNV 387
P S+VLA G D I IW+
Sbjct: 1152 PQDSSVLAASG--EDDQITIWDF 1214
>01805
Length = 2124
Score = 44.7 bits (104), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 40/170 (23%), Positives = 74/170 (43%), Gaps = 3/170 (1%)
Frame = -1
Query: 304 TLSGHSQEVCGLRWAPDGRH-LASGGNDNLVNVWPSAPGEGGWVPLQTFTQHQGAVKAVA 362
+++GH+Q V L W + RH LAS D V +W + G+ FTQH V+
Sbjct: 591 SVTGHTQAVLDLSWNRNARHVLASASADTTVALWDLSEGKMA----MNFTQHSREVQCCN 424
Query: 363 WCPWQSNVLATGGGTSDRHIRIWNVCSG-ACLSAVDAHSQVCSILWSPHYKELISGHGFA 421
W P + L T G+ D +++ + S C + +V +W+ H+ L
Sbjct: 423 WHPQEEQTLLT--GSFDNTVKVVDCRSAETCHKSWTVEGEVEKAVWN-HHNPLQLLACTD 253
Query: 422 QNQLVIWKYPTMAKVAELKGHTSRVLSLTMSPD-GATVASAAADETLRLW 470
+ + + V + H+S V + +S + + + D+T+++W
Sbjct: 252 KGMVYCFDIRHEKPVFSVGAHSSCVTGVCLSSQIPGLMITTSEDKTMKVW 103
Score = 29.3 bits (64), Expect = 3.7, Method: Compositional matrix adjust.
Identities = 13/37 (35%), Positives = 19/37 (51%)
Frame = -1
Query: 241 LAVGTSSAEVQLWDVQQQKRLRNMTSHSARVGSLSWN 277
LA ++ V LWD+ + K N T HS V +W+
Sbjct: 528 LASASADTTVALWDLSEGKMAMNFTQHSREVQCCNWH 418
>27465
Length = 658
Score = 43.1 bits (100), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 36/176 (20%), Positives = 63/176 (35%), Gaps = 4/176 (2%)
Frame = -1
Query: 299 EHHV---ATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPGEGGWVPLQTFTQHQ 355
+HH L H + + + G +G D +W +A E L T H+
Sbjct: 400 DHHFYLFKVLRAHILPLTNVAFNKSGSSFITGSYDRTCKIWDTASAE----ELHTLEGHR 233
Query: 356 GAVKAVAWC-PWQSNVLATGGGTSDRHIRIWNVCSGACLSAVDAHSQVCSILWSPHYKEL 414
V A+A+ P+ V+ G+ D+ ++W+ G C
Sbjct: 232 NVVYAIAFNNPFGDKVIT---GSFDKTCKLWSTADGKC---------------------- 128
Query: 415 ISGHGFAQNQLVIWKYPTMAKVAELKGHTSRVLSLTMSPDGATVASAAADETLRLW 470
Y T L+GHT+ ++ ++ +P +A+ + D T RLW
Sbjct: 127 ---------------YHT------LRGHTAEIVCVSFNPSSTLIATGSMDTTCRLW 23
Score = 36.6 bits (83), Expect = 0.021, Method: Compositional matrix adjust.
Identities = 42/183 (22%), Positives = 68/183 (37%), Gaps = 13/183 (7%)
Frame = -1
Query: 91 ASFLLSKENQPENSQTPTKKEHQKAWAL-----------NLNGFDVEEAKILRLSGKPQN 139
A ++ + + E TP+K+EH K W + F V A IL L+ N
Sbjct: 511 ADLVVQEIAEKEQLITPSKQEHVKNWCFACRKTRPKDDHHFYLFKVLRAHILPLTNVAFN 332
Query: 140 APEGYQNRLKVLYSQKATPGSSRKTCRYIPSLPDRILDAPE-IRNDYYLNLVDWSSGN-V 197
GS +TC+ + L E RN Y + G+ V
Sbjct: 331 KS-----------GSSFITGSYDRTCKIWDTASAEELHTLEGHRNVVYAIAFNNPFGDKV 185
Query: 198 LAVALDNSVYLWSASSGDILQLLQMEQPGEYISSVAWIKEGNYLAVGTSSAEVQLWDVQQ 257
+ + D + LWS + G L+ I V++ +A G+ +LWDV++
Sbjct: 184 ITGSFDKTCKLWSTADGKCYHTLRGHTAE--IVCVSFNPSSTLIATGSMDTTCRLWDVEK 11
Query: 258 QKR 260
+R
Sbjct: 10 AQR 2
>15780
Length = 735
Score = 42.0 bits (97), Expect = 6e-04, Method: Compositional matrix adjust.
Identities = 18/50 (36%), Positives = 27/50 (54%)
Frame = -1
Query: 421 AQNQLVIWKYPTMAKVAELKGHTSRVLSLTMSPDGATVASAAADETLRLW 470
A + +++W + VA L HT V +L S DG +AS D ++RLW
Sbjct: 714 ADHTVIVWDIASGTAVAHLTAHTDTVYALCFSRDGTVLASGGMDNSIRLW 565
Score = 28.5 bits (62), Expect = 5.9, Method: Compositional matrix adjust.
Identities = 19/76 (25%), Positives = 37/76 (48%)
Frame = -1
Query: 203 DNSVYLWSASSGDILQLLQMEQPGEYISSVAWIKEGNYLAVGTSSAEVQLWDVQQQKRLR 262
D++V +W +SG + L Y ++ + ++G LA G ++LWD+ + +
Sbjct: 711 DHTVIVWDIASGTAVAHLTAHTDTVY--ALCFSRDGTVLASGGMDNSIRLWDLARVMEEQ 538
Query: 263 NMTSHSARVGSLSWNS 278
+ + S SLS N+
Sbjct: 537 DPETDSNVPSSLSVNT 490
>13278
Length = 870
Score = 41.6 bits (96), Expect = 7e-04, Method: Compositional matrix adjust.
Identities = 30/109 (27%), Positives = 53/109 (48%), Gaps = 9/109 (8%)
Frame = +1
Query: 309 SQEVCGLRWAPDG---------RHLASGGNDNLVNVWPSAPGEGGWVPLQTFTQHQGAVK 359
++E+ ++W+P G LAS D+ V +W G + L T T+HQ V
Sbjct: 49 TKEIYTIKWSPTGPGTSNPNTSLILASASFDSTVRLWEVERG----LCLHTLTKHQEPVY 216
Query: 360 AVAWCPWQSNVLATGGGTSDRHIRIWNVCSGACLSAVDAHSQVCSILWS 408
+VA+ P LA+G + D+ + IWNV +G+ + + + + W+
Sbjct: 217 SVAFSP-DGKYLASG--SFDKCVHIWNVQTGSLVHSYKGTGGIFEVCWN 354
Score = 37.4 bits (85), Expect = 0.013, Method: Compositional matrix adjust.
Identities = 26/82 (31%), Positives = 40/82 (48%), Gaps = 1/82 (1%)
Frame = +1
Query: 197 VLAVA-LDNSVYLWSASSGDILQLLQMEQPGEYISSVAWIKEGNYLAVGTSSAEVQLWDV 255
+LA A D++V LW G L L Q E + SVA+ +G YLA G+ V +W+V
Sbjct: 118 ILASASFDSTVRLWEVERGLCLHTLTKHQ--EPVYSVAFSPDGKYLASGSFDKCVHIWNV 291
Query: 256 QQQKRLRNMTSHSARVGSLSWN 277
Q + + + + + WN
Sbjct: 292 QTGSLVHSYKG-TGGIFEVCWN 354
Score = 35.4 bits (80), Expect = 0.058, Method: Compositional matrix adjust.
Identities = 15/38 (39%), Positives = 24/38 (63%)
Frame = +1
Query: 304 TLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPG 341
TL+ H + V + ++PDG++LASG D V++W G
Sbjct: 187 TLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNVQTG 300
Score = 32.0 bits (71), Expect = 0.61, Method: Compositional matrix adjust.
Identities = 22/95 (23%), Positives = 42/95 (44%), Gaps = 8/95 (8%)
Frame = +1
Query: 384 IWNVCSGACLSAVDAHS-QVCSILWSPH-------YKELISGHGFAQNQLVIWKYPTMAK 435
IW++ +C+ + + ++ +I WSP LI + + +W+
Sbjct: 1 IWSMGKDSCIHDLQLTTKEIYTIKWSPTGPGTSNPNTSLILASASFDSTVRLWEVERGLC 180
Query: 436 VAELKGHTSRVLSLTMSPDGATVASAAADETLRLW 470
+ L H V S+ SPDG +AS + D+ + +W
Sbjct: 181 LHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIW 285
>19140
Length = 573
Score = 38.9 bits (89), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 17/39 (43%), Positives = 25/39 (64%)
Frame = -3
Query: 432 TMAKVAELKGHTSRVLSLTMSPDGATVASAAADETLRLW 470
T K+ +LKGHT V +L ++ DG S ++D T+RLW
Sbjct: 520 TCHKLMKLKGHTDNVKALVLNRDGTQCLSGSSDGTIRLW 404
>10264
Length = 416
Score = 38.9 bits (89), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 23/81 (28%), Positives = 39/81 (48%), Gaps = 2/81 (2%)
Frame = -1
Query: 393 LSAVDAHSQ-VCSILWSPHYKELISGHGFAQNQLVIWKYPTMAKVAELKGHTSRVLSLTM 451
L + HSQ V + WSPH+ + G+ + +W +A+ KGH R+L+
Sbjct: 266 LRELSGHSQRVTDMSWSPHHDARLVSVGY-DAEAFVWDVQKGTALAQFKGHMGRLLTCQF 90
Query: 452 SP-DGATVASAAADETLRLWR 471
S D V + +D ++ +WR
Sbjct: 89 SGLDPDLVMTGGSDASVHVWR 27
Score = 38.5 bits (88), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 29/85 (34%), Positives = 38/85 (44%), Gaps = 2/85 (2%)
Frame = -1
Query: 305 LSGHSQEVCGLRWAP--DGRHLASGGNDNLVNVWPSAPGEGGWVPLQTFTQHQGAVKAVA 362
LSGHSQ V + W+P D R L S G D VW G L F H G +
Sbjct: 257 LSGHSQRVTDMSWSPHHDAR-LVSVGYDAEAFVWDVQKG----TALAQFKGHMGRLLTCQ 93
Query: 363 WCPWQSNVLATGGGTSDRHIRIWNV 387
+ +++ TGG SD + +W V
Sbjct: 92 FSGLDPDLVMTGG--SDASVHVWRV 24
>01598
Length = 1545
Score = 38.9 bits (89), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 24/81 (29%), Positives = 38/81 (46%), Gaps = 2/81 (2%)
Frame = +1
Query: 393 LSAVDAHSQ-VCSILWSPHYKELISGHGFAQNQLVIWKYPTMAKVAELKGHTSRVLSLTM 451
L + HSQ V + WSPH+ + G+ V W +A+ KGH R+L+
Sbjct: 1279 LRELSGHSQRVTDMSWSPHHDARLVSVGYDAEAFV-WDVQKGTALAQFKGHMGRLLTCQF 1455
Query: 452 SP-DGATVASAAADETLRLWR 471
S D V + +D ++ +WR
Sbjct: 1456 SGLDPDLVMTGGSDASVHVWR 1518
Score = 38.5 bits (88), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 29/85 (34%), Positives = 38/85 (44%), Gaps = 2/85 (2%)
Frame = +1
Query: 305 LSGHSQEVCGLRWAP--DGRHLASGGNDNLVNVWPSAPGEGGWVPLQTFTQHQGAVKAVA 362
LSGHSQ V + W+P D R L S G D VW G L F H G +
Sbjct: 1288 LSGHSQRVTDMSWSPHHDAR-LVSVGYDAEAFVWDVQKG----TALAQFKGHMGRLLTCQ 1452
Query: 363 WCPWQSNVLATGGGTSDRHIRIWNV 387
+ +++ TGG SD + +W V
Sbjct: 1453 FSGLDPDLVMTGG--SDASVHVWRV 1521
>11493
Length = 535
Score = 38.9 bits (89), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 43/172 (25%), Positives = 73/172 (42%), Gaps = 4/172 (2%)
Frame = -2
Query: 301 HVATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWP-SAPGEGGWVPLQTFTQHQGAVK 359
+ TLS H + VC + + +++ +GG V VW S PG V Q ++
Sbjct: 498 QINTLS-HGEVVCAVTISNPTKYVYTGGK-GCVKVWDISQPGNKNPVSQLDCLQRDNYIR 325
Query: 360 AVAWCPWQSNVLATGGGTSDRHIRIWNVCSGA--CLSAVDAHSQVCSIL-WSPHYKELIS 416
+V P L GG S+ + IW++ S + + + + C L SP K S
Sbjct: 324 SVKLLP-DGRTLIVGGEASN--LSIWDLASPTPRIKAELTSAAPACYALAISPDSKVCFS 154
Query: 417 GHGFAQNQLVIWKYPTMAKVAELKGHTSRVLSLTMSPDGATVASAAADETLR 468
+ + +W V + +GHT + +SPDG+ + + D T+R
Sbjct: 153 C--CSDGNIAVWDLHNEILVRQFQGHTDGASCIDISPDGSRLWTGGLDNTVR 4
Score = 28.1 bits (61), Expect = 8.9, Method: Compositional matrix adjust.
Identities = 23/69 (33%), Positives = 30/69 (43%), Gaps = 2/69 (2%)
Frame = -2
Query: 404 SILWSPHYKELISGHGFAQNQLVIWKY--PTMAKVAELKGHTSRVLSLTMSPDGATVASA 461
S+ P + LI G G A N L IW PT AEL +L +SPD S
Sbjct: 324 SVKLLPDGRTLIVG-GEASN-LSIWDLASPTPRIKAELTSAAPACYALAISPDSKVCFSC 151
Query: 462 AADETLRLW 470
+D + +W
Sbjct: 150 CSDGNIAVW 124
>31474
Length = 403
Score = 38.5 bits (88), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 32/112 (28%), Positives = 55/112 (49%), Gaps = 5/112 (4%)
Frame = -3
Query: 302 VATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPGEG-GWVPLQTFTQ-HQGAVK 359
V LS H + + W P G LAS G+D ++ +W EG WV T T H V+
Sbjct: 326 VCCLSAHDEHAWCVAWNPTGTLLASCGSDKIIKIWGK---EGDNWVCKSTLTDAHTRTVR 156
Query: 360 AVAWCPWQSNVLATGGGTSDRHIRIWNVCSG--ACLSAVDAH-SQVCSILWS 408
++ W P N L++ + D +W+ G C++ ++ H ++V ++ W+
Sbjct: 155 SLGWSP-CGNYLSS--ASFDATTAVWSRKGGEFECIATLEGHENEVKAVAWA 9
>01249
Length = 1743
Score = 38.5 bits (88), Expect = 0.007, Method: Compositional matrix adjust.
Identities = 57/284 (20%), Positives = 98/284 (34%), Gaps = 2/284 (0%)
Frame = -1
Query: 189 LVDWSSGNVLAVALDNSVYLWSASSGDILQLLQMEQPGEYISSVAWIKEGNYLAVGTSSA 248
LV G ++ +Y+W + G ++ LL + + + +G+ V TSS
Sbjct: 1473 LVVSPDGLFCLASISEKIYIWEMTGGSLVGLLSDFNEA---TKIQFTDDGSQFVVATSSG 1303
Query: 249 EVQLWDVQQQKRLRNMTSHSARVGSLSWNSYILXXXXXXXXXXXXDVRVAEHHVATLSGH 308
+ +WD R +T+ S R L T++ H
Sbjct: 1302 HLNIWDFA-----RVVTTTSQRARGLKPGR-------------------------TINAH 1213
Query: 309 SQEVCGLRWAPDG--RHLASGGNDNLVNVWPSAPGEGGWVPLQTFTQHQGAVKAVAWCPW 366
S+ + GL G +AS +D +W G L+T G
Sbjct: 1212 SEPITGLHVGCGGPAARVASSSSDGTCKLWDMLSG----ALLRTMVYETGV--GCLIMDK 1051
Query: 367 QSNVLATGGGTSDRHIRIWNVCSGACLSAVDAHSQVCSILWSPHYKELISGHGFAQNQLV 426
Q + L G D IL SP + ++ +Q+++
Sbjct: 1050 QEHFLLAGLDNGD-------------------------ILCSPLFGQI------SQSEVF 964
Query: 427 IWKYPTMAKVAELKGHTSRVLSLTMSPDGATVASAAADETLRLW 470
+ K+ T A L+GH+ V L S DG +AS + + + +W
Sbjct: 963 VSKHTTKAGERVLQGHSDAVTCLAFSSDGQRLASGSQNGKVIIW 832
Score = 33.1 bits (74), Expect = 0.27, Method: Compositional matrix adjust.
Identities = 30/117 (25%), Positives = 47/117 (40%), Gaps = 15/117 (12%)
Frame = -1
Query: 241 LAVGTSSAEVQLWDVQQQKRLRNMTSHSARVGSLSWNS---YILXXXXXXX--------X 289
+A +S +LWD+ LR M + VG L + ++L
Sbjct: 1161 VASSSSDGTCKLWDMLSGALLRTMV-YETGVGCLIMDKQEHFLLAGLDNGDILCSPLFGQ 985
Query: 290 XXXXDVRVAEHHVA----TLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPGE 342
+V V++H L GHS V L ++ DG+ LASG + V +W G+
Sbjct: 984 ISQSEVFVSKHTTKAGERVLQGHSDAVTCLAFSSDGQRLASGSQNGKVIIWNMESGD 814
>02960
Length = 1577
Score = 38.1 bits (87), Expect = 0.009, Method: Compositional matrix adjust.
Identities = 44/156 (28%), Positives = 74/156 (47%), Gaps = 5/156 (3%)
Frame = +2
Query: 302 VATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPGEGGWVPLQTFTQHQGAVKAV 361
V TLSGH++ V +RW D + + D+ + +W + + Q AV V
Sbjct: 938 VLTLSGHAEAVSAVRWL-DPHRVVTSSWDHSLRLWDLHTAQQ-----TSLIQGSKAVLDV 1099
Query: 362 AWCPWQSNVLATGGGTSDRHIRIWN-VCS--GACLSAVDAHSQ-VCSILWSPHYKELISG 417
A+ P S++L T G++DRH+R+ + CS A +H+ V + WSP + L
Sbjct: 1100 AYSP-LSHMLIT--GSADRHVRLVDPRCSEGETVKCAFTSHTGWVTGVDWSPTREHLFLS 1270
Query: 418 HGFAQNQLVIWKYPT-MAKVAELKGHTSRVLSLTMS 452
G N L +W + A + ++ H R+L++ S
Sbjct: 1271 -GSYDNVLKLWDTRSPKATLYDMNWHEDRILAVDWS 1375
Score = 37.7 bits (86), Expect = 0.010, Method: Compositional matrix adjust.
Identities = 66/303 (21%), Positives = 107/303 (35%), Gaps = 26/303 (8%)
Frame = +2
Query: 194 SGNVLAVALDNSVYLWSASSGDILQLLQMEQPGEYISSVAWIKEGNYLAVGT--SSAEVQ 251
+G L+ + DN+V LWS I+ + P + VAWIK V T + + Q
Sbjct: 515 TGXXLSGSYDNTVRLWSTKGEAIMTIPGHTSP---VKCVAWIKHDESSGVSTFVTGSHDQ 685
Query: 252 LWDVQQQKRLRNMTSHSARVGSLSWNSYILXXXXXXXXXXXXDVRVAEHHVATLSGHSQE 311
V Q +R N D R++ GH+
Sbjct: 686 TALVWQWQRETN----------------------------EVDCRLS------CRGHAAS 763
Query: 312 VCGLRWAPDGRHLASGGNDNLVNVWPSAPGEGG----------------------WVPLQ 349
V + +PD + + +G D ++ +W + G VP+
Sbjct: 764 VDCVAVSPDSQQMCTGSWDKMLKLWSTDCNVDGDQSEDTERPSKKKKSAKSTTQTRVPVL 943
Query: 350 TFTQHQGAVKAVAWCPWQSNVLATGGGTSDRHIRIWNVCSGACLSAVDAHSQVCSILWSP 409
T + H AV AV W V ++ D +R+W++ + S + V + +SP
Sbjct: 944 TLSGHAEAVSAVRWLDPHRVVTSSW----DHSLRLWDLHTAQQTSLIQGSKAVLDVAYSP 1111
Query: 410 HYKELISGHGFAQNQLVIWKYPTMAKV-AELKGHTSRVLSLTMSPDGATV-ASAAADETL 467
LI+G +LV + V HT V + SP + S + D L
Sbjct: 1112LSHMLITGSADRHVRLVDPRCSEGETVKCAFTSHTGWVTGVDWSPTREHLFLSGSYDNVL 1291
Query: 468 RLW 470
+LW
Sbjct: 1292KLW 1300
>17602
Length = 481
Score = 37.7 bits (86), Expect = 0.011, Method: Composition-based stats.
Identities = 33/159 (20%), Positives = 71/159 (44%), Gaps = 8/159 (5%)
Frame = +3
Query: 251 QLWDVQQQKRLRNMTSHSARVGSLSWN--SYILXXXXXXXXXXXXDVRVAEHHVATLSGH 308
++WDV+ K L+ + +HS V ++ +N ++ D + +
Sbjct: 3 RIWDVKTGKCLKTLPAHSDPVTAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLXTLIDDD 182
Query: 309 SQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPGEGGWVPLQTFTQHQGAVKAVAWCPWQS 368
+ V ++++P+G+++ + DN + +W + G+ L+T+ H+ +C + +
Sbjct: 183 NPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKC----LKTYVGHRNE----KYCIF-A 335
Query: 369 NVLATGG-----GTSDRHIRIWNVC-SGACLSAVDAHSQ 401
N TGG G+ D + IWN+ G A +H +
Sbjct: 336 NFSVTGGKWIVSGSEDNMVYIWNLLDQGDSTEATGSHRR 452
Score = 34.7 bits (78), Expect = 0.083, Method: Composition-based stats.
Identities = 25/89 (28%), Positives = 39/89 (43%), Gaps = 1/89 (1%)
Frame = +3
Query: 383 RIWNVCSGACLSAVDAHSQVCSILWSPHYKELISGHGFAQNQLVIWKYPTMAKVAELKGH 442
RIW+V +G CL + AHS + + LI + IW + + L
Sbjct: 3 RIWDVKTGKCLKTLPAHSDPVTAVHFNRDGSLIVSSSY-DGLCRIWDTASGQCLXTLIDD 179
Query: 443 TSRVLSLT-MSPDGATVASAAADETLRLW 470
+ +S SP+G + +A D TL+LW
Sbjct: 180 DNPPVSFVKFSPNGKYILAATLDNTLKLW 266
Score = 30.8 bits (68), Expect = 1.5, Method: Composition-based stats.
Identities = 17/71 (23%), Positives = 32/71 (45%)
Frame = +3
Query: 197 VLAVALDNSVYLWSASSGDILQLLQMEQPGEYISSVAWIKEGNYLAVGTSSAEVQLWDVQ 256
+++ + D +W +SG L L ++ +S V + G Y+ T ++LWD
Sbjct: 99 IVSSSYDGLCRIWDTASGQCLXTL-IDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYS 275
Query: 257 QQKRLRNMTSH 267
+ K L+ H
Sbjct: 276 KGKCLKTYVGH 308
>03044
Length = 1952
Score = 37.4 bits (85), Expect = 0.014, Method: Compositional matrix adjust.
Identities = 23/71 (32%), Positives = 29/71 (40%)
Frame = -2
Query: 304 TLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPGEGGWVPLQTFTQHQGAVKAVAW 363
TL H Q V G+ WAP + + G D VW +G W P + A V W
Sbjct: 1669 TLGEHGQRVTGIDWAPKSNRIVTCGADRNAYVWTYQ--DGKWQPHLVILRINRAATCVKW 1496
Query: 364 CPWQSNVLATG 374
P + N A G
Sbjct: 1495 SP-EENKFAVG 1466
Score = 28.9 bits (63), Expect = 5.0, Method: Compositional matrix adjust.
Identities = 17/73 (23%), Positives = 34/73 (46%), Gaps = 2/73 (2%)
Frame = -2
Query: 190 VDWS--SGNVLAVALDNSVYLWSASSGDILQLLQMEQPGEYISSVAWIKEGNYLAVGTSS 247
+DW+ S ++ D + Y+W+ G L + + + V W E N AVG+S+
Sbjct: 1636 IDWAPKSNRIVTCGADRNAYVWTYQDGKWQPHLVILRINRAATCVKWSPEENKFAVGSSA 1457
Query: 248 AEVQLWDVQQQKR 260
+ + +++ R
Sbjct: 1456 RLISVSYYEEEHR 1418
>15337
Length = 860
Score = 37.4 bits (85), Expect = 0.015, Method: Compositional matrix adjust.
Identities = 17/61 (27%), Positives = 29/61 (47%), Gaps = 8/61 (13%)
Frame = -1
Query: 302 VATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWP--------SAPGEGGWVPLQTFTQ 353
+ T+ + + + W+PDG+++ +GG D+LV VW G WV + F
Sbjct: 224 IGTMKSYFGGLLCVCWSPDGKYIVTGGEDDLVTVWSFHEKRVVCRGHGHKSWVNVVAFDI 45
Query: 354 H 354
H
Sbjct: 44 H 42
>12960
Length = 550
Score = 37.0 bits (84), Expect = 0.018, Method: Compositional matrix adjust.
Identities = 24/88 (27%), Positives = 40/88 (45%)
Frame = +2
Query: 299 EHHVATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPGEGGWVPLQTFTQHQGAV 358
E + T GH EV + + D + SGG D V ++ A G+ L+ + H G V
Sbjct: 269 ELFLKTYIGHGHEVLDAQGSGDNSQICSGGIDKTVVLFDVASGQA----LRKYRDHAGTV 436
Query: 359 KAVAWCPWQSNVLATGGGTSDRHIRIWN 386
V + + +L+ G+ D +R W+
Sbjct: 437 NCVKFNEESTVILS---GSLDNTVRAWD 511
>14555
Length = 627
Score = 37.0 bits (84), Expect = 0.018, Method: Compositional matrix adjust.
Identities = 16/44 (36%), Positives = 25/44 (56%)
Frame = -3
Query: 427 IWKYPTMAKVAELKGHTSRVLSLTMSPDGATVASAAADETLRLW 470
+W + L GH +RV L +SPDG ++ + + D TLR+W
Sbjct: 388 VWDALKGMRSTILYGHDNRVSCLRISPDGTSLCTGSWDYTLRIW 257
Score = 28.5 bits (62), Expect = 6.2, Method: Compositional matrix adjust.
Identities = 13/32 (40%), Positives = 17/32 (53%)
Frame = -3
Query: 305 LSGHSQEVCGLRWAPDGRHLASGGNDNLVNVW 336
L GH V LR +PDG L +G D + +W
Sbjct: 352 LYGHDNRVSCLRISPDGTSLCTGSWDYTLRIW 257
>12140
Length = 727
Score = 37.0 bits (84), Expect = 0.021, Method: Compositional matrix adjust.
Identities = 19/44 (43%), Positives = 22/44 (50%)
Frame = +2
Query: 322 RHLASGGNDNLVNVWPSAPGEGGWVPLQTFTQHQGAVKAVAWCP 365
+ SGG DNLV +W E GWV Q H V+ VAW P
Sbjct: 263 KRFVSGGCDNLVKIWR--EDETGWVEDQKLEGHSDWVRDVAWAP 388
>37142
Length = 327
Score = 36.6 bits (83), Expect = 0.023, Method: Compositional matrix adjust.
Identities = 17/37 (45%), Positives = 27/37 (72%)
Frame = +2
Query: 351 FTQHQGAVKAVAWCPWQSNVLATGGGTSDRHIRIWNV 387
T+H GAVKA+ + P+Q+N+LA+G S+ I IW++
Sbjct: 92 LTKHTGAVKALDFNPFQTNLLASGA--SESEIYIWDL 196
>10162
Length = 1629
Score = 35.8 bits (81), Expect = 0.042, Method: Compositional matrix adjust.
Identities = 42/159 (26%), Positives = 63/159 (39%), Gaps = 12/159 (7%)
Frame = +3
Query: 189 LVDWSSGNVLAVA--LDNSVYLWSASSGDILQLLQM------EQPGEYISSVAWIKEGNY 240
VD S+ N L ++ D + +++ SSG + + + SVA+ Y
Sbjct: 384 CVDCSADNALIMSGCADATAKVFNVSSGKLXSAFNCAASQDSQDKDNSVESVAFCPVSPY 563
Query: 241 LAVGTSSAEVQLWDVQQQKRLRNMTSHSARVGSLSWNS--YILXXXXXXXXXXXXDVRVA 298
A T+S VQ+WD+ R+ H V L W+S +L D R
Sbjct: 564 AATATNSGSVQVWDLPTSVA-RHSFQHPEGVCKLQWSSSTALLYTACLDGVMRVWDARSG 740
Query: 299 EHHVATLSGHSQEVCGLRW--APDGRHLASGGNDNLVNV 335
A L+GH++ C L + DG L SG D V
Sbjct: 741 ASK-AVLTGHARNSCILDFDVTRDGTCLVSGSEDGTARV 854
Score = 35.0 bits (79), Expect = 0.064, Method: Compositional matrix adjust.
Identities = 57/279 (20%), Positives = 104/279 (37%), Gaps = 6/279 (2%)
Frame = +3
Query: 197 VLAVALDNSVYLWSASSGDILQLLQMEQPGEYISSVAWIKEGNYLAVGTSSAEVQLWDVQ 256
+LA V+LW S D ++ ++ G+ + G Y+ VG S V+LWD++
Sbjct: 72 LLAGTQGGEVWLWQVPSQDYSKMKMLQSHGQPSLCGKILPNGKYVCVGYSDGVVKLWDLK 251
Query: 257 QQKRLRNMTSHSARVGSLSWNSYILXXXXXXXXXXXXDVRVAEHHVATLSGHSQEVCGLR 316
+ +W ++ + E V +C +
Sbjct: 252 TGTAVH------------TWQHSVMPEEEMPERNSSDEEDGEEVEVEREEDTVAILC-VD 392
Query: 317 WAPDGRHLASGGNDNLVNVWPSAPGE----GGWVPLQTFTQHQGAVKAVAWCPWQSNVLA 372
+ D + SG D V+ + G+ Q +V++VA+CP S A
Sbjct: 393 CSADNALIMSGCADATAKVFNVSSGKLXSAFNCAASQDSQDKDNSVESVAFCP-VSPYAA 569
Query: 373 TGGGTSDRHIRIWNVCSGACLSAVDAHSQVCSILWSPHYKELISGHGFAQNQLVIWKYPT 432
T T+ +++W++ + + VC + WS L + + +W +
Sbjct: 570 T--ATNSGSVQVWDLPTSVARHSFQHPEGVCKLQWSSSTALLYT--ACLDGVMRVWDARS 737
Query: 433 MAKVAELKGH--TSRVLSLTMSPDGATVASAAADETLRL 469
A A L GH S +L ++ DG + S + D T R+
Sbjct: 738 GASKAVLTGHARNSCILDFDVTRDGTCLVSGSEDGTARV 854
>18981
Length = 407
Score = 35.4 bits (80), Expect = 0.051, Method: Composition-based stats.
Identities = 23/97 (23%), Positives = 44/97 (45%), Gaps = 2/97 (2%)
Frame = -2
Query: 376 GTSDRHIRIWNVCSGACLSAVDAHSQ--VCSILWSPHYKELISGHGFAQNQLVIWKYPTM 433
+DR +R+W + + L + H+ C ++ + ++SG L++W+ T
Sbjct: 370 AATDRTLRVWCLKNTCLLHTLRGHNDDVECVCIYG---RRVVSGSW--DKTLIVWEVDTG 206
Query: 434 AKVAELKGHTSRVLSLTMSPDGATVASAAADETLRLW 470
V +L GHT + ++ D S +AD +R W
Sbjct: 205 RPVHQLHGHTEAITAVQF--DEGKAVSGSADGDVRTW 101
Score = 33.5 bits (75), Expect = 0.22, Method: Composition-based stats.
Identities = 27/91 (29%), Positives = 40/91 (43%), Gaps = 1/91 (1%)
Frame = -2
Query: 304 TLSGHSQEV-CGLRWAPDGRHLASGGNDNLVNVWPSAPGEGGWVPLQTFTQHQGAVKAVA 362
TL GH+ +V C + GR + SG D + VW G P+ H A+ AV
Sbjct: 313 TLRGHNDDVECVCIY---GRRVVSGSWDKTLIVWEVDTGR----PVHQLHGHTEAITAV- 158
Query: 363 WCPWQSNVLATGGGTSDRHIRIWNVCSGACL 393
Q + G++D +R W + +G CL
Sbjct: 157 ----QFDEGKAVSGSADGDVRTWALDTGQCL 77
>38177
Length = 430
Score = 35.0 bits (79), Expect = 0.064, Method: Compositional matrix adjust.
Identities = 23/91 (25%), Positives = 38/91 (41%)
Frame = +3
Query: 232 VAWIKEGNYLAVGTSSAEVQLWDVQQQKRLRNMTSHSARVGSLSWNSYILXXXXXXXXXX 291
+AW EG L G SS E LW+ + +H V ++ W+++
Sbjct: 6 LAWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDVSVRAMRWSNHDQWMVTADHSGY 185
Query: 292 XXDVRVAEHHVATLSGHSQEVCGLRWAPDGR 322
+ ++V GH + + G+R AP GR
Sbjct: 186 IKYWQSNMNNVKMFQGHKEPIRGVRLAPPGR 278
>21921
Length = 1341
Score = 35.0 bits (79), Expect = 0.071, Method: Compositional matrix adjust.
Identities = 22/82 (26%), Positives = 35/82 (42%), Gaps = 5/82 (6%)
Frame = -1
Query: 334 NVWPSAPGEGGWVPLQT-----FTQHQGAVKAVAWCPWQSNVLATGGGTSDRHIRIWNVC 388
++ P P P T + H G V+++ CP + G + D IR W V
Sbjct: 561 DLLPKLPKPKDLRPFPTTQALVYKGHTGIVRSI--CPDPTGQWLVSG-SDDGTIRFWEVS 391
Query: 389 SGACLSAVDAHSQVCSILWSPH 410
SG C+ + V S+ W+P+
Sbjct: 390 SGRCMKTLQVGGCVTSVAWNPN 325
Score = 29.3 bits (64), Expect = 3.4, Method: Compositional matrix adjust.
Identities = 17/50 (34%), Positives = 24/50 (48%), Gaps = 5/50 (10%)
Frame = -1
Query: 430 YPTMAKVAELKGHTSRVLSLTMSPDGATVASAAADETLRLW-----RCFE 474
+PT + KGHT V S+ P G + S + D T+R W RC +
Sbjct: 519 FPTTQALV-YKGHTGIVRSICPDPTGQWLVSGSDDGTIRFWEVSSGRCMK 373
>26107
Length = 1338
Score = 34.7 bits (78), Expect = 0.082, Method: Compositional matrix adjust.
Identities = 27/83 (32%), Positives = 38/83 (45%), Gaps = 3/83 (3%)
Frame = -3
Query: 306 SGHSQEVCGLRWA--PDGRHLASGGNDNLVNVWP-SAPGEGGWVPLQTFTQHQGAVKAVA 362
+GH + +R A PDG++L SG N +W P + PL H V AV
Sbjct: 439 AGHRNDTFFVRCAISPDGKYLLSGSGRNTGVIWEVDKPNKR---PL-FLIGHTEDVSAVD 272
Query: 363 WCPWQSNVLATGGGTSDRHIRIW 385
WC ++V + DR +RIW
Sbjct: 271 WC--STDVCKLATVSDDRSLRIW 209
Score = 28.5 bits (62), Expect = 6.5, Method: Compositional matrix adjust.
Identities = 16/47 (34%), Positives = 20/47 (42%), Gaps = 1/47 (2%)
Frame = -3
Query: 425 LVIWKYPTMAKVAELKGHTSRVLSLTMSPDG-ATVASAAADETLRLW 470
+ +W T KV GH V S+ P A AS A D + LW
Sbjct: 1015 VALWDVETTTKVTTFIGHKCSVRSVASCPSSPAQCASGARDGHIMLW 875
>03395
Length = 2795
Score = 34.7 bits (78), Expect = 0.092, Method: Compositional matrix adjust.
Identities = 36/157 (22%), Positives = 63/157 (40%), Gaps = 6/157 (3%)
Frame = +2
Query: 321 GRHLASGGNDNLVNVWPSA----PGEGGWVPLQTFTQHQGAVKAVAWCPWQSNVLATGGG 376
G L SGG + V VW G+ + +H+G V A+ +N
Sbjct: 32 GTKLVSGGGEGQVRVWDIVKDMLTGKTRGDLVANMKEHKGKVTAI---QIHTNDRCCVSA 202
Query: 377 TSDRHIRIWNVCSGACLSAVDAHSQV-CSILWSPHYKELISGHGFAQNQLVIWKYPTMAK 435
++D IW++ + V A++ C L SG +++ W+
Sbjct: 203 STDGSTIIWDLITNTRSQIVLANTLFKCVCFGGKDLHILTSG---TDHKIGYWEVGDGGL 373
Query: 436 VAELKG-HTSRVLSLTMSPDGATVASAAADETLRLWR 471
+ EL+G T + ++ + DG T+ + D L+LWR
Sbjct: 374 LRELEGSQTGAINTIDIDRDGQTILTGGEDSLLKLWR 484
Score = 29.6 bits (65), Expect = 3.3, Method: Compositional matrix adjust.
Identities = 28/147 (19%), Positives = 52/147 (35%), Gaps = 1/147 (0%)
Frame = +2
Query: 196 NVLAVALDNSVYLWSASSGDILQLLQMEQPGEYISSVAWIKEGNYLAVGTSSAEVQLWDV 255
++L D+ + W G +L+ L+ Q G I+++ ++G + G + ++LW
Sbjct: 311 HILTSGTDHKIGYWEVGDGGLLRELEGSQTGA-INTIDIDRDGQTILTGGEDSLLKLW-- 481
Query: 256 QQQKRLRNMTSHSARVGSLSWNSYILXXXXXXXXXXXXDVRVAEHHVA-TLSGHSQEVCG 314
R E V T GHS ++
Sbjct: 482 ----------------------------------------RYNEGEVTHTGIGHSNQITK 541
Query: 315 LRWAPDGRHLASGGNDNLVNVWPSAPG 341
R P+ ++ SGG D +++W G
Sbjct: 542 ARICPNRHYIVSGGEDGALHIWKFPDG 622
>31864
Length = 545
Score = 34.7 bits (78), Expect = 0.099, Method: Compositional matrix adjust.
Identities = 16/39 (41%), Positives = 20/39 (51%)
Frame = +2
Query: 297 VAEHHVATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNV 335
+ E A L GH + L + PDG+ ASGG D V V
Sbjct: 305 IYEEEFARLKGHFGPINSLAFHPDGKSYASGGEDGFVRV 421
Score = 31.2 bits (69), Expect = 0.95, Method: Compositional matrix adjust.
Identities = 27/107 (25%), Positives = 42/107 (39%), Gaps = 14/107 (13%)
Frame = +2
Query: 377 TSDRHIRIWNVCSGACLSAVDAHSQVCSILWSPHYKELISGHGFAQNQLVIWKYPTMA-- 434
+ D ++++ S CL V S SP ++ G G Q+ + + T A
Sbjct: 107 SKDTTAKLFDSESLMCLKTYKTERPVNSAAISPILDHVVLGGG--QDAMEVTTTSTKAGK 280
Query: 435 ------------KVAELKGHTSRVLSLTMSPDGATVASAAADETLRL 469
+ A LKGH + SL PDG + AS D +R+
Sbjct: 281 FDSRFFHLIYEEEFARLKGHFGPINSLAFHPDGKSYASGGEDGFVRV 421
>27270
Length = 1078
Score = 34.3 bits (77), Expect = 0.12, Method: Compositional matrix adjust.
Identities = 41/166 (24%), Positives = 67/166 (40%), Gaps = 23/166 (13%)
Frame = +2
Query: 330 DNLVNVWPSAPGEGGWVPLQTFTQ----HQGAVKAVAWCPWQSNVLATGGGTSDRHIRIW 385
D+ V SA G G ++T T ++G KAV W+++ + D H+ W
Sbjct: 176 DSAVVAVGSADGSVGLYSVETHTYTHMLNKGHSKAVTDMCWRADGRTLYSSSLDGHVIGW 355
Query: 386 NVCSGACLSAVDA-----HSQVCSILWSPHYKELISGHGFAQNQLVIWKYPTMAKVAELK 440
NV + + A H C L S L++ A + + +W T + E
Sbjct: 356 NVNTLHMIEKWKATSGRHHGVHCVCLCSS--SRLLT----ADHTIKMWDLTTKNVLQEFS 517
Query: 441 GHTSRVLSL--TMSPDGA------------TVASAAADETLRLWRC 472
GH++ V+ L + P ++AAAD T+ +WRC
Sbjct: 518 GHSTEVIKLLPVLKPSSEQNDIGDSNLACYVFSAAAADRTINVWRC 655
>07665
Length = 435
Score = 33.9 bits (76), Expect = 0.15, Method: Compositional matrix adjust.
Identities = 24/96 (25%), Positives = 44/96 (45%), Gaps = 9/96 (9%)
Frame = -2
Query: 385 WNVCSGACLSAVDAHSQVCSILWSPHYKELISGHGFAQNQLVIWKYPTMAKVAEL----- 439
W++ G L ++ + + ++ +SP+ L +G + + IW V EL
Sbjct: 392 WDLNDGKNLYTLEHNDIINALCFSPNRYWLCVAYGPS---IKIWDLACKKTVEELRPEVV 222
Query: 440 ----KGHTSRVLSLTMSPDGATVASAAADETLRLWR 471
K + LSL S DG T+ + +D T+R+W+
Sbjct: 221 SPTSKAEQPQCLSLAWSTDGQTLFAGYSDNTIRVWQ 114
>02090
Length = 1841
Score = 33.9 bits (76), Expect = 0.16, Method: Compositional matrix adjust.
Identities = 13/50 (26%), Positives = 23/50 (46%)
Frame = -3
Query: 421 AQNQLVIWKYPTMAKVAELKGHTSRVLSLTMSPDGATVASAAADETLRLW 470
+ + +W V + +GHT + +SPDG + + D T+R W
Sbjct: 1566 SDGNIAVWDLHNQTLVRQFQGHTDGASCIDISPDGTKLWTGGLDNTVRSW 1417
Score = 33.1 bits (74), Expect = 0.27, Method: Compositional matrix adjust.
Identities = 41/157 (26%), Positives = 61/157 (38%)
Frame = -3
Query: 315 LRWAPDGRHLASGGNDNLVNVWPSAPGEGGWVPLQTFTQHQGAVKAVAWCPWQSNVLATG 374
L +PDG+ S +D + VW ++ F H + P L TG
Sbjct: 1608 LAISPDGKVCFSCCSDGNIAVWDLHNQ----TLVRQFQGHTDGASCIDISP-DGTKLWTG 1444
Query: 375 GGTSDRHIRIWNVCSGACLSAVDAHSQVCSILWSPHYKELISGHGFAQNQLVIWKYPTMA 434
G D +R W++ G L D SQ+ S+ + P + L G + +++ P
Sbjct: 1443 G--LDNTVRSWDLREGRQLQQHDFSSQIFSLGYCPTGEWLAVGMESSNVEVLHHSKPDKY 1270
Query: 435 KVAELKGHTSRVLSLTMSPDGATVASAAADETLRLWR 471
+L H S VLSL + G S D L WR
Sbjct: 1269 ---QLHLHESCVLSLKFAYCGKWFVSTGKDNLLNAWR 1168
Score = 32.0 bits (71), Expect = 0.57, Method: Compositional matrix adjust.
Identities = 33/148 (22%), Positives = 59/148 (39%), Gaps = 3/148 (2%)
Frame = -3
Query: 197 VLAVALDNSVYLWSASSGDILQLLQMEQPGEYISSVAWIKEGNYLAVGTSSAEVQLWDVQ 256
+ D ++ +W + +++ Q G S + +G L G V+ WD++
Sbjct: 1581 CFSCCSDGNIAVWDLHNQTLVRQFQGHTDGA--SCIDISPDGTKLWTGGLDNTVRSWDLR 1408
Query: 257 QQKRLRNMTSHSARVGSLSWNSYILXXXXXXXXXXXXDVRVAEH---HVATLSGHSQEVC 313
+ ++L+ S+++ SL Y +V V H L H V
Sbjct: 1407 EGRQLQQH-DFSSQIFSLG---YCPTGEWLAVGMESSNVEVLHHSKPDKYQLHLHESCVL 1240
Query: 314 GLRWAPDGRHLASGGNDNLVNVWPSAPG 341
L++A G+ S G DNL+N W + G
Sbjct: 1239 SLKFAYCGKWFVSTGKDNLLNAWRTPYG 1156
>30176
Length = 365
Score = 33.1 bits (74), Expect = 0.27, Method: Composition-based stats.
Identities = 14/33 (42%), Positives = 22/33 (66%)
Frame = +2
Query: 439 LKGHTSRVLSLTMSPDGATVASAAADETLRLWR 471
LK HTS V +LT G +AS + D+T+++W+
Sbjct: 8 LKSHTSTVWNLTFDKTGTRLASCSDDKTIKIWQ 106
>07542
Length = 1027
Score = 32.7 bits (73), Expect = 0.37, Method: Compositional matrix adjust.
Identities = 18/62 (29%), Positives = 34/62 (54%), Gaps = 1/62 (1%)
Frame = +1
Query: 201 ALDNSVYLWSASSGDILQLLQMEQPGEYISSVAWIKEGNYL-AVGTSSAEVQLWDVQQQK 259
A + V ++ G + + + QPG I+ VA+ K+GNYL A G E+ +D++ +
Sbjct: 1 AFNGDVAIYDVPHGGLTAVFE-GQPGG-ITHVAFSKDGNYLFAGGRKDPEINCFDIRNPE 174
Query: 260 RL 261
++
Sbjct: 175 KI 180
>15972
Length = 1069
Score = 32.0 bits (71), Expect = 0.57, Method: Compositional matrix adjust.
Identities = 18/63 (28%), Positives = 30/63 (47%)
Frame = +3
Query: 347 PLQTFTQHQGAVKAVAWCPWQSNVLATGGGTSDRHIRIWNVCSGACLSAVDAHSQVCSIL 406
P +TF+ H+G V+ +A P L + DR +R+WN +G + S+
Sbjct: 213 PERTFSGHKGPVRHLAVHPSGKLTLTV---SQDRTLRLWNNMNGRIAFISNMKEAAESVR 383
Query: 407 WSP 409
W+P
Sbjct: 384 WAP 392
>31054
Length = 392
Score = 32.0 bits (71), Expect = 0.60, Method: Compositional matrix adjust.
Identities = 15/43 (34%), Positives = 24/43 (55%)
Frame = -2
Query: 428 WKYPTMAKVAELKGHTSRVLSLTMSPDGATVASAAADETLRLW 470
WK+P + L GH + + +L ++ DG V S A + T+ LW
Sbjct: 334 WKFPDGNFIQNLSGHNAIINTLAVNSDGVLV-SGADNGTMHLW 209
>19863
Length = 502
Score = 31.6 bits (70), Expect = 0.86, Method: Compositional matrix adjust.
Identities = 18/64 (28%), Positives = 30/64 (46%)
Frame = +1
Query: 413 ELISGHGFAQNQLVIWKYPTMAKVAELKGHTSRVLSLTMSPDGATVASAAADETLRLWRC 472
+L+SG + +V+W + L+GH V + S D + S + D T+R+W
Sbjct: 13 QLVSGS--SDMSIVVWDVENGVQKLRLQGHAGWVNDVHFSQDQCWLLSCSNDNTVRIWNI 186
Query: 473 FELD 476
E D
Sbjct: 187 EESD 198
>35607
Length = 475
Score = 30.4 bits (67), Expect = 1.5, Method: Compositional matrix adjust.
Identities = 30/101 (29%), Positives = 42/101 (41%)
Frame = +2
Query: 371 LATGGGTSDRHIRIWNVCSGACLSAVDAHSQVCSILWSPHYKELISGHGFAQNQLVIWKY 430
L TGG D +R W++ G L D SQ+ S+ + P L G + +++
Sbjct: 23 LWTGG--LDNTVRSWDLREGRQLQQHDFSSQIFSLGYCPTGDWLAVGMESSNVEVLHHSK 196
Query: 431 PTMAKVAELKGHTSRVLSLTMSPDGATVASAAADETLRLWR 471
P +L H S VLSL + G S D L WR
Sbjct: 197 PDKY---QLHLHESCVLSLKFAYCGKWFVSTGKDNLLNAWR 310
Score = 30.4 bits (67), Expect = 1.6, Method: Compositional matrix adjust.
Identities = 28/108 (25%), Positives = 45/108 (41%), Gaps = 3/108 (2%)
Frame = +2
Query: 237 EGNYLAVGTSSAEVQLWDVQQQKRLRNMTSHSARVGSLSWNSYILXXXXXXXXXXXXDVR 296
+G L G V+ WD+++ ++L+ S+++ SL Y +V
Sbjct: 11 DGTKLWTGGLDNTVRSWDLREGRQLQQH-DFSSQIFSLG---YCPTGDWLAVGMESSNVE 178
Query: 297 VAEH---HVATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPG 341
V H L H V L++A G+ S G DNL+N W + G
Sbjct: 179 VLHHSKPDKYQLHLHESCVLSLKFAYCGKWFVSTGKDNLLNAWRTPYG 322
>22113
Length = 614
Score = 30.4 bits (67), Expect = 1.5, Method: Compositional matrix adjust.
Identities = 14/34 (41%), Positives = 18/34 (52%)
Frame = +3
Query: 308 HSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPG 341
H V LR+A G+ S G DNL+N W + G
Sbjct: 99 HESCVLSLRFATCGKWFVSTGKDNLLNAWRTPYG 200
>34511
Length = 1037
Score = 30.0 bits (66), Expect = 2.1, Method: Compositional matrix adjust.
Identities = 13/32 (40%), Positives = 21/32 (65%)
Frame = +3
Query: 439 LKGHTSRVLSLTMSPDGATVASAAADETLRLW 470
L GH +RV L ++ +G +VA+ + D LR+W
Sbjct: 60 LAGHDNRVSCLGVTENGMSVATGSWDSFLRVW 155
>20172
Length = 479
Score = 30.0 bits (66), Expect = 2.2, Method: Composition-based stats.
Identities = 18/48 (37%), Positives = 25/48 (52%), Gaps = 2/48 (4%)
Frame = +2
Query: 169 PSLPDRILDAPEIRNDYYLNLVDWSSG--NVLAVALDNSVYLWSASSG 214
P DR D P R + + DW+ G +V+ ALD + LWS +SG
Sbjct: 233 PKYSDRYGDEP--RRNRMGEITDWNDGKKSVVGEALDKAKDLWSRASG 370
>12841
Length = 1364
Score = 30.0 bits (66), Expect = 2.4, Method: Compositional matrix adjust.
Identities = 22/75 (29%), Positives = 31/75 (41%), Gaps = 1/75 (1%)
Frame = +1
Query: 299 EHHVATLSGHSQEVCGLRWAPDGRHLA-SGGNDNLVNVWPSAPGEGGWVPLQTFTQHQGA 357
E ++ T SGH+ V +RW+P + S D + +W P+ TF
Sbjct: 1018 EQYLETYSGHTAPVYHIRWSPFVSDIFLSCSADWSIRLWHQDRT----TPILTFHSSTKT 1185
Query: 358 VKAVAWCPWQSNVLA 372
V V W P S V A
Sbjct: 1186 VHDVCWSPRSSTVFA 1230
>15118
Length = 1074
Score = 29.6 bits (65), Expect = 2.7, Method: Compositional matrix adjust.
Identities = 48/200 (24%), Positives = 73/200 (36%), Gaps = 16/200 (8%)
Frame = +3
Query: 190 VDWSS-GNVLAVALDNSVYLWSASSGDILQLLQMEQPGEY---------ISSVAWIKEGN 239
VD SS GN +AV +S+ DI L + G + + VA+
Sbjct: 75 VDISSCGNYVAVG-------YSSGHLDIYNLQSGKHRGSFGDTVAHVSGVRGVAFDAFNC 233
Query: 240 YLAVGTSSAEVQLWDVQQQKRLR------NMTSHSARVGSLSWNSYILXXXXXXXXXXXX 293
L +++ W + R R M+ +R+ L +S +L
Sbjct: 234 LLITAGGDCDIKFWRFGSRDRARVLLKELKMSEGISRI-LLHRDSNMLAVVLEDFTVSVI 410
Query: 294 DVRVAEHHVATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPGEGGWVPLQTFTQ 353
DV V SGHS + L ++ DGR L + D V W G + F
Sbjct: 411 DVDTLRV-VRVFSGHSNSITDLSFSGDGRWLITASMDCTVRTWSLVHGR----LIDCFAV 575
Query: 354 HQGAVKAVAWCPWQSNVLAT 373
+ AV ++ P Q + LAT
Sbjct: 576 -EAAVTSLTMSPSQ-DFLAT 629
Score = 28.9 bits (63), Expect = 5.0, Method: Compositional matrix adjust.
Identities = 13/44 (29%), Positives = 23/44 (52%)
Frame = +3
Query: 427 IWKYPTMAKVAELKGHTSRVLSLTMSPDGATVASAAADETLRLW 470
+ T+ V GH++ + L+ S DG + +A+ D T+R W
Sbjct: 405 VIDVDTLRVVRVFSGHSNSITDLSFSGDGRWLITASMDCTVRTW 536
>12409
Length = 674
Score = 29.6 bits (65), Expect = 2.8, Method: Compositional matrix adjust.
Identities = 12/33 (36%), Positives = 19/33 (57%)
Frame = -1
Query: 308 HSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAP 340
H VC R++ G+H+AS D +V +W +P
Sbjct: 338 HQSAVCYSRFSLSGQHIASLDADGIVKIWTWSP 240
>01707
Length = 757
Score = 29.3 bits (64), Expect = 3.5, Method: Compositional matrix adjust.
Identities = 15/47 (31%), Positives = 25/47 (53%)
Frame = +3
Query: 295 VRVAEHHVATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPG 341
V++++ T G+ QE+CG+R P + + GN N + S PG
Sbjct: 114 VQMSQQRDLTACGY-QEICGIRR*PSHQEDCNAGNSNAEAIKTSQPG 251
>36111
Length = 687
Score = 29.3 bits (64), Expect = 4.0, Method: Compositional matrix adjust.
Identities = 14/48 (29%), Positives = 24/48 (50%)
Frame = +2
Query: 229 ISSVAWIKEGNYLAVGTSSAEVQLWDVQQQKRLRNMTSHSARVGSLSW 276
+++VA+ N A G S V +WD +KRL + + SL++
Sbjct: 239 VNAVAFHNVYNTFATGGSDGYVNIWDGFHKKRLCXFHRYPTSIASLAF 382
>01462
Length = 995
Score = 28.9 bits (63), Expect = 4.5, Method: Compositional matrix adjust.
Identities = 12/52 (23%), Positives = 23/52 (44%)
Frame = +2
Query: 419 GFAQNQLVIWKYPTMAKVAELKGHTSRVLSLTMSPDGATVASAAADETLRLW 470
G ++ +W + ++GH + + M D SA+ D T+R+W
Sbjct: 251 GAGDRKIHVWDIEAGQYLNAMEGHKDYIHKVVMKNDAQECVSASEDGTVRMW 406
>21105
Length = 650
Score = 28.9 bits (63), Expect = 5.6, Method: Compositional matrix adjust.
Identities = 14/68 (20%), Positives = 34/68 (50%)
Frame = +1
Query: 203 DNSVYLWSASSGDILQLLQMEQPGEYISSVAWIKEGNYLAVGTSSAEVQLWDVQQQKRLR 262
D + + ++G ++ M + ++S+A G YL G+ ++LW++ + ++
Sbjct: 127 DRHIRFFDNNTGKLIH--AMVAHLDSVTSLAVDPNGLYLLSGSHDCSIRLWNLDSKTCVQ 300
Query: 263 NMTSHSAR 270
+TSH +
Sbjct: 301 EITSHRKK 324
>31384
Length = 474
Score = 28.5 bits (62), Expect = 7.0, Method: Compositional matrix adjust.
Identities = 12/29 (41%), Positives = 18/29 (62%)
Frame = -1
Query: 442 HTSRVLSLTMSPDGATVASAAADETLRLW 470
HT VL + S DG V +A+ D+T ++W
Sbjct: 138 HTGPVLDVDWSDDGTKVFTASCDKTAKVW 52
>27475
Length = 369
Score = 28.1 bits (61), Expect = 9.6, Method: Compositional matrix adjust.
Identities = 23/82 (28%), Positives = 42/82 (51%), Gaps = 2/82 (2%)
Frame = +2
Query: 351 FTQHQGAVKAVAWCPWQSNVLATGGGTSDRHIRIWNVCS-GACLSAVDAH-SQVCSILWS 408
FT H G V V W P + ++ + G+ D +++W+ S A L ++ H ++ ++ WS
Sbjct: 56 FTSHTGWVTGVDWSPTREHLFLS--GSYDNVLKLWDTRSPKATLYDMNWHEDRILAVDWS 229
Query: 409 PHYKELISGHGFAQNQLVIWKY 430
EL+ G N+L ++ Y
Sbjct: 230 --IPELLLSGG-VDNKLHVFSY 286
>30295
Length = 593
Score = 28.1 bits (61), Expect = 9.7, Method: Compositional matrix adjust.
Identities = 12/33 (36%), Positives = 17/33 (51%)
Frame = +2
Query: 304 TLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVW 336
TL H ++ + WA D R+L S D + VW
Sbjct: 230 TLRXHLAKIYAMHWATDSRNLVSASQDGKLIVW 328
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000361540 | hsapiens_gene_ensembl | Cell division
cycle protein 20 homolog (p55CDC).
[Source:Uniprot/SWISSPROT;Acc:Q12834]
(499 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
14500 177 2e-67
29912 209 2e-54
34005 157 5e-42
14884 112 3e-25
03387 62 7e-10
19949 57 2e-08
02147 57 2e-08
13335 55 6e-08
19498 54 2e-07
12574 54 2e-07
17266 52 5e-07
30256 51 8e-07
17598 50 2e-06
00561 49 4e-06
01327 48 1e-05
03156 47 1e-05
12806 47 2e-05
16105 46 4e-05
01768 46 4e-05
01805 45 1e-04
27465 43 2e-04
15780 42 6e-04
13278 42 7e-04
19140 39 0.004
10264 39 0.005
01598 39 0.005
11493 39 0.005
31474 39 0.006
01249 39 0.007
02960 38 0.009
17602 38 0.011
03044 37 0.014
15337 37 0.015
12960 37 0.018
14555 37 0.018
12140 37 0.021
37142 37 0.023
10162 36 0.042
18981 35 0.051
38177 35 0.064
21921 35 0.071
26107 35 0.082
03395 35 0.092
31864 35 0.099
27270 34 0.12
07665 34 0.15
02090 34 0.16
30176 33 0.27
07542 33 0.37
15972 32 0.57
31054 32 0.60
19863 32 0.86
35607 30 1.5
22113 30 1.5
34511 30 2.1
20172 30 2.2
12841 30 2.4
15118 30 2.7
12409 30 2.8
01707 29 3.5
36111 29 4.0
01462 29 4.5
21105 29 5.6
31384 28 7.0
27475 28 9.6
30295 28 9.7
>14500
Length = 1238
Score = 177 bits (449), Expect(2) = 2e-67, Method: Compositional matrix adjust.
Identities = 78/114 (68%), Positives = 95/114 (83%)
Frame = +3
Query: 363 WCPWQSNVLATGGGTSDRHIRIWNVCSGACLSAVDAHSQVCSILWSPHYKELISGHGFAQ 422
WCPWQ ++LA+GGGT+DRHI WN +G LS+VD SQVC++LWS ++ELIS HGFAQ
Sbjct: 225 WCPWQPSLLASGGGTADRHIHFWNCNTGTNLSSVDTKSQVCALLWSKEHRELISSHGFAQ 404
Query: 423 NQLVIWKYPTMAKVAELKGHTSRVLSLTMSPDGATVASAAADETLRLWRCFELD 476
NQL+IWKYP M++VAEL GHT+RVL + MSPDG TV SAAADETLRLW+CF +D
Sbjct: 405 NQLIIWKYPAMSRVAELTGHTARVLHMAMSPDGETVVSAAADETLRLWKCFTVD 566
Score = 97.8 bits (242), Expect(2) = 2e-67, Method: Compositional matrix adjust.
Identities = 47/68 (69%), Positives = 55/68 (80%), Gaps = 1/68 (1%)
Frame = +2
Query: 296 RVAEHHVATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPS-APGEGGWVPLQTFTQH 354
RVA+HHV TLSGHSQEVCGLRW+PDG++LASG NDNL+ VWP+ G PL TF+QH
Sbjct: 20 RVADHHVGTLSGHSQEVCGLRWSPDGKYLASGANDNLLCVWPAQVTGGNSTQPLHTFSQH 199
Query: 355 QGAVKAVA 362
Q AVKA+A
Sbjct: 200 QAAVKALA 223
Score = 33.9 bits (76), Expect = 0.15, Method: Compositional matrix adjust.
Identities = 16/35 (45%), Positives = 19/35 (54%)
Frame = +2
Query: 436 VAELKGHTSRVLSLTMSPDGATVASAAADETLRLW 470
V L GH+ V L SPDG +AS A D L +W
Sbjct: 38 VGTLSGHSQEVCGLRWSPDGKYLASGANDNLLCVW 142
Score = 28.9 bits (63), Expect = 4.6, Method: Compositional matrix adjust.
Identities = 12/35 (34%), Positives = 19/35 (54%)
Frame = +3
Query: 302 VATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVW 336
VA L+GH+ V + +PDG + S D + +W
Sbjct: 444 VAELTGHTARVLHMAMSPDGETVVSAAADETLRLW 548
>29912
Length = 510
Score = 209 bits (532), Expect = 2e-54, Method: Compositional matrix adjust.
Identities = 100/153 (65%), Positives = 119/153 (77%), Gaps = 1/153 (0%)
Frame = +3
Query: 225 PGEYISSVAWIKEGNYLAVGTSSAEVQLWDVQQQKRLRNMTSHSARVGSLSWNSYILXXX 284
P EYI +V+WIKEGNYLA+GTS+ EVQ+WDV QQK+LR M H+ARVGSLSWNS+I+
Sbjct: 6 PEEYIGAVSWIKEGNYLALGTSTGEVQVWDVTQQKKLRTMAGHAARVGSLSWNSFIVSSG 185
Query: 285 XXXXXXXXXDVRVAEHHVATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPS-APGEG 343
DVRVA+HHV TLSGHSQEVCGLRW+PDG++LASG NDNL+ VWP+ G
Sbjct: 186 SRSGNIHHHDVRVADHHVGTLSGHSQEVCGLRWSPDGKYLASGANDNLLCVWPAQVTGGN 365
Query: 344 GWVPLQTFTQHQGAVKAVAWCPWQSNVLATGGG 376
PL TF+QHQ AVKA+AWCPWQ + LA+GGG
Sbjct: 366 STQPLHTFSQHQAAVKALAWCPWQPSXLASGGG 464
Score = 38.5 bits (88), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 35/114 (30%), Positives = 51/114 (44%), Gaps = 1/114 (0%)
Frame = +3
Query: 358 VKAVAWCPWQSNVLATGGGTSDRHIRIWNVCSGACLSAVDAHS-QVCSILWSPHYKELIS 416
+ AV+W + N LA G TS +++W+V L + H+ +V S+ W+ S
Sbjct: 18 IGAVSWIK-EGNYLALG--TSTGEVQVWDVTQQKKLRTMAGHAARVGSLSWNSFIVSSGS 188
Query: 417 GHGFAQNQLVIWKYPTMAKVAELKGHTSRVLSLTMSPDGATVASAAADETLRLW 470
G + V V L GH+ V L SPDG +AS A D L +W
Sbjct: 189 RSGNIHHHDV---RVADHHVGTLSGHSQEVCGLRWSPDGKYLASGANDNLLCVW 341
>34005
Length = 456
Score = 157 bits (398), Expect(2) = 5e-42, Method: Compositional matrix adjust.
Identities = 73/115 (63%), Positives = 85/115 (73%)
Frame = +1
Query: 310 QEVCGLRWAPDGRHLASGGNDNLVNVWPSAPGEGGWVPLQTFTQHQGAVKAVAWCPWQSN 369
QEVCGL W+PD LASG NDN VN+W S G PL T T HQ AVKAVAWCPWQ+
Sbjct: 115 QEVCGLSWSPDATFLASGSNDNSVNIWDSTLGMDV-PPLHTLTSHQAAVKAVAWCPWQTR 291
Query: 370 VLATGGGTSDRHIRIWNVCSGACLSAVDAHSQVCSILWSPHYKELISGHGFAQNQ 424
+LATGGGT+DRHIR WN +GAC+ AVD SQVCS+LW ++EL+SGHG+ NQ
Sbjct: 292 MLATGGGTNDRHIRFWNTNTGACVKAVDTQSQVCSVLWCKEHRELVSGHGYVMNQ 456
Score = 32.0 bits (71), Expect(2) = 5e-42, Method: Compositional matrix adjust.
Identities = 16/36 (44%), Positives = 19/36 (52%)
Frame = +3
Query: 274 LSWNSYILXXXXXXXXXXXXDVRVAEHHVATLSGHS 309
L+WNS+IL DVRVA H V LS H+
Sbjct: 6 LAWNSHILSSGSRSGNIHHHDVRVARHKVGLLSTHT 113
Score = 34.3 bits (77), Expect = 0.11, Method: Compositional matrix adjust.
Identities = 30/131 (22%), Positives = 50/131 (38%), Gaps = 7/131 (5%)
Frame = +1
Query: 204 NSVYLWSASSGDILQLLQMEQPGEYISSVAWIKEGNYLAVGTSSAEVQLWDVQQQKR--- 260
+ Y W A+ L E + ++W + +LA G++ V +WD
Sbjct: 61 TTTYAWRATRWGFCPLTPQE-----VCGLSWSPDATFLASGSNDNSVNIWDSTLGMDVPP 225
Query: 261 LRNMTSHSARVGSLSWNSYILXXXXXXXXXXXXDVRVAEHH----VATLSGHSQEVCGLR 316
L +TSH A V +++W + +R + V + SQ VC +
Sbjct: 226 LHTLTSHQAAVKAVAWCPWQTRMLATGGGTNDRHIRFWNTNTGACVKAVDTQSQ-VCSVL 402
Query: 317 WAPDGRHLASG 327
W + R L SG
Sbjct: 403 WCKEHRELVSG 435
>14884
Length = 632
Score = 112 bits (281), Expect = 3e-25, Method: Compositional matrix adjust.
Identities = 75/215 (34%), Positives = 106/215 (49%), Gaps = 12/215 (5%)
Frame = -1
Query: 44 RAANRSHSAGRTPGRTPGKSSSKVQTTPSKPGGDRYIPHRSAAQMEVASFLLSKENQPEN 103
RA H AG+TP R K+ TP K DR+IP+R +++ F L + E
Sbjct: 599 RATPGKHVAGKTPNR-------KLAVTPGK-QQDRFIPNRMTTDQDMSHFALMHHHSKEE 444
Query: 104 S-----------QTPTKKEHQKAWALNLNGFDVEEAK-ILRLSGKPQNAPEGYQNRLKVL 151
T +++ +A N +G + K I + +P N L VL
Sbjct: 443 EEEEAGMTTHAGNTLYQQQLSEAMLHNQHGAKILSFKNICSVQSQPSN--------LSVL 288
Query: 152 YSQKATPGSSRKTCRYIPSLPDRILDAPEIRNDYYLNLVDWSSGNVLAVALDNSVYLWSA 211
YS P + R+IPS P+ +LDAP + +DYYL+ +DWSS N +A AL VYLW A
Sbjct: 287 YSTGKVPTTKSSNVRHIPSRPEHVLDAPVVLDDYYLHTIDWSSTNTVAAALGPEVYLWHA 108
Query: 212 SSGDILQLLQMEQPGEYISSVAWIKEGNYLAVGTS 246
I QL+++ +YISSV+WI +G L VG S
Sbjct: 107 RDATITQLMRVAD-SDYISSVSWISDGTVLGVGMS 6
>03387
Length = 1891
Score = 61.6 bits (148), Expect = 7e-10, Method: Compositional matrix adjust.
Identities = 50/175 (28%), Positives = 74/175 (42%), Gaps = 9/175 (5%)
Frame = +1
Query: 305 LSGHSQEVCGLRWAPD-GRHLASGGNDNLVNVWP--SAPGEGGWVPLQT-FTQHQGAVKA 360
L GH +E GL W P+ HL S +D+ + +W S E V T FT H V+
Sbjct: 349 LKGHQKEGYGLSWNPNLNGHLLSASDDHTICLWDINSTQRESRVVDAHTIFTGHTSVVED 528
Query: 361 VAWCPWQSNVLATGGGTSDRHIRIWNVCSGACLS---AVDAHSQVCSILWSPHYKELISG 417
VAW ++ G D+ + IW+ S VDAH+ + L Y E I
Sbjct: 529 VAWHLLHESLF--GSVADDQKLMIWDTRSNTTSKPSHVVDAHTAEVNCLSFNPYSEFILA 702
Query: 418 HGFAQNQLVIWKYPTMA-KVAELKGHTSRVLSLTMSPDGATV-ASAAADETLRLW 470
G A + +W + K+ + H + + SP T+ AS+ D L +W
Sbjct: 703 TGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLHVW 867
>19949
Length = 903
Score = 57.0 bits (136), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 35/117 (29%), Positives = 58/117 (49%), Gaps = 1/117 (0%)
Frame = +2
Query: 302 VATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPGEGGWVPLQTFTQHQGAVKAV 361
+ T GH+ VC LR++PDGR +AS D LV +W G+ L H+ AV +
Sbjct: 98 IYTYKGHTGCVCCLRFSPDGRWIASASEDGLVKLWDLTAGK----LLTDLKLHRDAVNTI 265
Query: 362 AWCPWQSNVLATGGGTSDRHIRIWNVCSGACLSAVDAHSQ-VCSILWSPHYKELISG 417
+ P + G++DR ++ W++ + +S + + + SIL+ P L SG
Sbjct: 266 EFHPHE---FLLASGSADRTVKFWDLETFQLISTTEPEANSIRSILFHPDGVCLYSG 427
Score = 36.2 bits (82), Expect = 0.030, Method: Compositional matrix adjust.
Identities = 18/52 (34%), Positives = 25/52 (48%)
Frame = +2
Query: 419 GFAQNQLVIWKYPTMAKVAELKGHTSRVLSLTMSPDGATVASAAADETLRLW 470
G + +W + KGHT V L SPDG +ASA+ D ++LW
Sbjct: 47 GSMDCNVKLWDIRRKGCIYTYKGHTGCVCCLRFSPDGRWIASASEDGLVKLW 202
>02147
Length = 1547
Score = 56.6 bits (135), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 49/243 (20%), Positives = 95/243 (39%), Gaps = 6/243 (2%)
Frame = +2
Query: 236 KEGNYLAVGTSSAEVQLWDVQQQKRLRNMT-SHSARVGSLSWNSYILXXXXXXXXXXXXD 294
+E A G + ++WD ++ + L+ + H + S + L D
Sbjct: 203 REATRAATGAADFSAKIWDAEKGEELQTFSHKHIVKSVDFSHDGTALLTGSNEKLLKVFD 382
Query: 295 VRVAEHHVATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPGEGGWVPLQTFTQH 354
+ + + +GH+ + G + DG+ + S +D V +W L+T +
Sbjct: 383 LVNTDAEPKSFAGHTSNIKGALFLSDGKRIISASDDKTVRLWS----------LETCQEV 532
Query: 355 QGAV-----KAVAWCPWQSNVLATGGGTSDRHIRIWNVCSGACLSAVDAHSQVCSILWSP 409
Q ++ P ++ ++ T ++I + + + +A + + S S
Sbjct: 533 QQLTFDTPPTSLTLSPDKNTIIVT----HSQNIAFYQADTLREMKKFEAEAPISSA--SL 694
Query: 410 HYKELISGHGFAQNQLVIWKYPTMAKVAELKGHTSRVLSLTMSPDGATVASAAADETLRL 469
H E G ++ + Y T ++ KGH V + SPDG AS + D TLRL
Sbjct: 695 HQSERFFVAGGEDFKMYKFDYETGKEIESFKGHFGPVHCVRFSPDGELYASGSEDGTLRL 874
Query: 470 WRC 472
W+
Sbjct: 875 WQT 883
Score = 39.7 bits (91), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 46/182 (25%), Positives = 80/182 (43%), Gaps = 9/182 (4%)
Frame = +2
Query: 302 VATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPGEGGWVPLQTFTQHQGAVKAV 361
+ T GH V G + A+G D +W + GE LQTF+ H+ VK+V
Sbjct: 152 IGTFEGHKGAVWGATLNREATRAATGAADFSAKIWDAEKGE----ELQTFS-HKHIVKSV 316
Query: 362 AWCPWQSNVLATGGGTSDRHIRIWN-VCSGACLSAVDAH-SQVCSILWSPHYKELISGHG 419
+ + +L G++++ +++++ V + A + H S + L+ K +IS
Sbjct: 317 DFSHDGTALLT---GSNEKLLKVFDLVNTDAEPKSFAGHTSNIKGALFLSDGKRIISASD 487
Query: 420 FAQNQLVIWKYPTMAKVAELKGHTSRVLSLTMSPDGATVASAAAD-------ETLRLWRC 472
+ +W T +V +L T SLT+SPD T+ + +TLR +
Sbjct: 488 --DKTVRLWSLETCQEVQQLTFDTPPT-SLTLSPDKNTIIVTHSQNIAFYQADTLREMKK 658
Query: 473 FE 474
FE
Sbjct: 659 FE 664
Score = 37.0 bits (84), Expect = 0.016, Method: Compositional matrix adjust.
Identities = 34/149 (22%), Positives = 58/149 (38%), Gaps = 4/149 (2%)
Frame = +2
Query: 197 VLAVALDNSVYLWSASSGDILQLLQMEQPGEYISSVAWIKEGNYLAVGTSSAEVQLWDVQ 256
+++ + D +V LWS + +Q L + P +S+ + N + V T S + +
Sbjct: 470 IISASDDKTVRLWSLETCQEVQQLTFDTPP---TSLTLSPDKNTIIV-THSQNIAFY--- 628
Query: 257 QQKRLRNMTSHSARV----GSLSWNSYILXXXXXXXXXXXXDVRVAEHHVATLSGHSQEV 312
Q LR M A SL + D + + + GH V
Sbjct: 629 QADTLREMKKFEAEAPISSASLHQSERFFVAGGEDFKMYKFDYETGKE-IESFKGHFGPV 805
Query: 313 CGLRWAPDGRHLASGGNDNLVNVWPSAPG 341
+R++PDG ASG D + +W + G
Sbjct: 806 HCVRFSPDGELYASGSEDGTLRLWQTTIG 892
>13335
Length = 863
Score = 55.1 bits (131), Expect = 6e-08, Method: Compositional matrix adjust.
Identities = 47/184 (25%), Positives = 82/184 (44%), Gaps = 22/184 (11%)
Frame = +1
Query: 309 SQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPGEGGWVPLQTFTQHQGAVKAVAWCPWQS 368
S VC +++P HL SG +D+ + +W A + ++++ H+ +V A+A+ P
Sbjct: 67 SIRVC--KFSPSSSHLVSGSDDDTICMWEVATQK----LVRSYVGHEDSVMALAYSP-NG 225
Query: 369 NVLATGGGTSDRHIRIWNVCSGACLSA---VDAHSQ-VCSILWSPHYK----------EL 414
+ L +G D + +W+ G C VDAH V +SP + L
Sbjct: 226 HYLVSGSPNGD--LYVWDASFGHCRHLTLRVDAHDLGVTCCEFSPTFGTACAENSSTCNL 399
Query: 415 ISGHGFAQNQLVIWKYPTMAKVAE--------LKGHTSRVLSLTMSPDGATVASAAADET 466
+ G N + +W + E L GH+ V++ SP A +AS + D++
Sbjct: 400 LLATGGKDNLIKLWTFSAQVGSPEVTLQCRDILSGHSDLVMACAFSPSSALLASGSFDKS 579
Query: 467 LRLW 470
+RLW
Sbjct: 580 VRLW 591
Score = 42.0 bits (97), Expect = 6e-04, Method: Compositional matrix adjust.
Identities = 44/191 (23%), Positives = 75/191 (39%), Gaps = 21/191 (10%)
Frame = +1
Query: 302 VATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPGEGGWVPLQTFTQHQGAVKAV 361
V + GH V L ++P+G +L SG + + VW ++ G + L+ H V
Sbjct: 166 VRSYVGHEDSVMALAYSPNGHYLVSGSPNGDLYVWDASFGHCRHLTLRV-DAHDLGVTCC 342
Query: 362 AWCPWQSN-----------VLATGGGTSDRHIRIWNVCSGA--------CLSAVDAHSQ- 401
+ P +LATGG D I++W + C + HS
Sbjct: 343 EFSPTFGTACAENSSTCNLLLATGG--KDNLIKLWTFSAQVGSPEVTLQCRDILSGHSDL 516
Query: 402 VCSILWSPHYKELISGHGFAQNQLVIWKYPTMAKVAELKG-HTSRVLSLTMSPDGATVAS 460
V + +SP L SG + +W + ++ H+ V S DG +AS
Sbjct: 517 VMACAFSPSSALLASGS--FDKSVRLWDSVKGVALFSIEACHSRFVTCCAFSIDGTLLAS 690
Query: 461 AAADETLRLWR 471
+ D +++W+
Sbjct: 691 GSMDRIIKIWK 723
Score = 40.0 bits (92), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 25/83 (30%), Positives = 36/83 (43%)
Frame = +1
Query: 305 LSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPGEGGWVPLQTFTQHQGAVKAVAWC 364
LSGHS V ++P LASG D V +W S G + F+ + V C
Sbjct: 496 LSGHSDLVMACAFSPSSALLASGSFDKSVRLWDSVKG------VALFSIEACHSRFVTCC 657
Query: 365 PWQSNVLATGGGTSDRHIRIWNV 387
+ + G+ DR I+IW +
Sbjct: 658 AFSIDGTLLASGSMDRIIKIWKL 726
Score = 40.0 bits (92), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 47/218 (21%), Positives = 95/218 (43%), Gaps = 9/218 (4%)
Frame = +1
Query: 193 SSGNVLAVALDNSVYLWSASSGDILQLLQMEQPGEYISSVAWIKEGNYLAVGTSSAEVQL 252
SS ++++ + D+++ +W ++ +++ + + + ++A+ G+YL G+ + ++ +
Sbjct: 94 SSSHLVSGSDDDTICMWEVATQKLVRSYVGHE--DSVMALAYSPNGHYLVSGSPNGDLYV 267
Query: 253 WDVQQQKRLRNMTSHSARVGSLSWNSYILXXXXXXXXXXXXDVRVAEHHVATLSGHSQEV 312
WD R++T +RV H +
Sbjct: 268 WD-ASFGHCRHLT-----------------------------LRVDAHDLGVTCCEFSPT 357
Query: 313 CGLRWAPDGRH----LASGGNDNLVNVWPSAPGEGG-WVPLQT---FTQHQGAVKAVAWC 364
G A + LA+GG DNL+ +W + G V LQ + H V A A+
Sbjct: 358 FGTACAENSSTCNLLLATGGKDNLIKLWTFSAQVGSPEVTLQCRDILSGHSDLVMACAFS 537
Query: 365 PWQSNVLATGGGTSDRHIRIWNVCSGACLSAVDA-HSQ 401
P S +LA+ G+ D+ +R+W+ G L +++A HS+
Sbjct: 538 P-SSALLAS--GSFDKSVRLWDSVKGVALFSIEACHSR 642
>19498
Length = 903
Score = 53.5 bits (127), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 47/184 (25%), Positives = 72/184 (39%), Gaps = 14/184 (7%)
Frame = -1
Query: 302 VATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPGEGG-------------WVPL 348
+ + H V +RW+ +G+ LASGG+D L+ +W + G G W +
Sbjct: 807 LCQMDSHLGCVNCVRWSENGKFLASGGDDKLIMIWQISRGFGSGKSFGSNVTILEHWRSV 628
Query: 349 QTFTQHQGAVKAVAWCPWQSNVLATGGGTSDRHIRIWNVCSGACLSAVDAHSQVCSILWS 408
T H G V +AW P Q LA+ CS+
Sbjct: 627 ATLRGHAGDVLDLAWSP-QDLWLAS-----------------------------CSV--- 547
Query: 409 PHYKELISGHGFAQNQLVIWKYPTMA-KVAELKGHTSRVLSLTMSPDGATVASAAADETL 467
N +V+W + +VA ++GH V +T P G +AS + D+TL
Sbjct: 546 -------------DNTIVVWNALKFSEQVAVIRGHAGMVKGVTWDPVGRYLASQSDDKTL 406
Query: 468 RLWR 471
R+WR
Sbjct: 405 RVWR 394
Score = 43.5 bits (101), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 31/141 (21%), Positives = 59/141 (41%), Gaps = 20/141 (14%)
Frame = -1
Query: 219 LLQMEQPGEYISSVAWIKEGNYLAVGTSSAEVQLWDV-----------------QQQKRL 261
L QM+ ++ V W + G +LA G + +W + + + +
Sbjct: 807 LCQMDSHLGCVNCVRWSENGKFLASGGDDKLIMIWQISRGFGSGKSFGSNVTILEHWRSV 628
Query: 262 RNMTSHSARVGSLSW---NSYILXXXXXXXXXXXXDVRVAEHHVATLSGHSQEVCGLRWA 318
+ H+ V L+W + ++ ++ +E VA + GH+ V G+ W
Sbjct: 627 ATLRGHAGDVLDLAWSPQDLWLASCSVDNTIVVWNALKFSEQ-VAVIRGHAGMVKGVTWD 451
Query: 319 PDGRHLASGGNDNLVNVWPSA 339
P GR+LAS +D + VW ++
Sbjct: 450 PVGRYLASQSDDKTLRVWRTS 388
Score = 28.5 bits (62), Expect = 5.8, Method: Compositional matrix adjust.
Identities = 26/93 (27%), Positives = 35/93 (37%), Gaps = 14/93 (15%)
Frame = -1
Query: 307 GHSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAP--GEGGWVPLQTFTQHQGAVKAVAWC 364
G + V L W+PDG H+ S N N P+A GW F H+ A+ V +
Sbjct: 342 GGTTHVLRLNWSPDGNHVVSAHAMN--NAXPTAQIIERNGWGTSLDFVGHRKAITVVRFN 169
Query: 365 P------------WQSNVLATGGGTSDRHIRIW 385
P Q G+ DR + IW
Sbjct: 168 PKILSKQIKKSAEKQQQYSCCAIGSKDRSLSIW 70
>12574
Length = 521
Score = 53.5 bits (127), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 31/115 (26%), Positives = 60/115 (52%), Gaps = 1/115 (0%)
Frame = +3
Query: 304 TLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPGEGGWVPLQTFTQHQGAVKAVAW 363
TL+GH++ + ++++P+G LAS D L+ +W + G+ +T H+ + VAW
Sbjct: 171 TLAGHTKALSAVKFSPNGDWLASSSADKLIKIWGAYDGKFE----KTIAGHKLGLSDVAW 338
Query: 364 CPWQSNVLATGGGTSDRHIRIWNVCSGACLSAVDAHSQ-VCSILWSPHYKELISG 417
S +L + + D+ ++IW +G C+ + HS V ++P ++SG
Sbjct: 339 SS-DSKLLCS--ASDDKTLKIWEFSTGKCMKTLKGHSNYVFCCNFNPQSNLIVSG 494
Score = 38.1 bits (87), Expect = 0.009, Method: Compositional matrix adjust.
Identities = 30/114 (26%), Positives = 49/114 (42%), Gaps = 1/114 (0%)
Frame = +3
Query: 350 TFTQHQGAVKAVAWCPWQSNVLATGGGTSDRHIRIWNVCSGACLSAVDAHS-QVCSILWS 408
T H A+ AV + P + LA+ ++D+ I+IW G + H + + WS
Sbjct: 171 TLAGHTKALSAVKFSP-NGDWLASS--SADKLIKIWGAYDGKFEKTIAGHKLGLSDVAWS 341
Query: 409 PHYKELISGHGFAQNQLVIWKYPTMAKVAELKGHTSRVLSLTMSPDGATVASAA 462
K L S L IW++ T + LKGH++ V +P + S +
Sbjct: 342 SDSKLLCSASD--DKTLKIWEFSTGKCMKTLKGHSNYVFCCNFNPQSNLIVSGS 497
Score = 33.1 bits (74), Expect = 0.27, Method: Compositional matrix adjust.
Identities = 14/44 (31%), Positives = 27/44 (61%)
Frame = +3
Query: 431 PTMAKVAELKGHTSRVLSLTMSPDGATVASAAADETLRLWRCFE 474
PT L GHT + ++ SP+G +AS++AD+ +++W ++
Sbjct: 150 PTYTLKFTLAGHTKALSAVKFSPNGDWLASSSADKLIKIWGAYD 281
>17266
Length = 480
Score = 52.0 bits (123), Expect = 5e-07, Method: Composition-based stats.
Identities = 46/168 (27%), Positives = 74/168 (44%), Gaps = 8/168 (4%)
Frame = -1
Query: 308 HSQEVCG----LRWAPDGRHLASGGNDNLVNVWPSAPGEGGWVPLQTFTQHQGAVKAVAW 363
HSQ G L APD R SG D +W G + QTF+ H+ + A+ +
Sbjct: 474 HSQATLGT**VLSLAPDMRTFVSGACDASAKLWDVRDG----MCKQTFSGHESDINAITY 307
Query: 364 CPWQSNVLATGGGTSDRHIRIWNVCSGACLSAVDAHSQVC---SILWSPHYKELISGHG- 419
P N A G+ D R++++ + + + +C S+ +S + L+ G+
Sbjct: 306 FP---NGHAFATGSDDATCRLFDIRADQEIGMYSHDNIICGITSVAFSKSGRLLLGGYDD 136
Query: 420 FAQNQLVIWKYPTMAKVAELKGHTSRVLSLTMSPDGATVASAAADETL 467
F N IW + L GH +RV L ++ DG+ VA+ + D L
Sbjct: 135 FNCN---IWDVLKQERTGVLAGHDNRVSCLGVTEDGSAVATGSWDSFL 1
Score = 34.7 bits (78), Expect = 0.10, Method: Composition-based stats.
Identities = 20/64 (31%), Positives = 29/64 (45%), Gaps = 12/64 (18%)
Frame = -1
Query: 229 ISSVAWIKEGNYLAVGTSSAEVQLWDVQQQKRLRNMTSHSARVGSL------------SW 276
I+SVA+ K G L G +WDV +Q+R + H RV L SW
Sbjct: 192 ITSVAFSKSGRLLLGGYDDFNCNIWDVLKQERTGVLAGHDNRVSCLGVTEDGSAVATGSW 13
Query: 277 NSYI 280
+S++
Sbjct: 12 DSFL 1
>30256
Length = 961
Score = 51.2 bits (121), Expect = 8e-07, Method: Compositional matrix adjust.
Identities = 51/179 (28%), Positives = 83/179 (46%), Gaps = 5/179 (2%)
Frame = +3
Query: 302 VATLSGHSQEVCGLRWAPD--GRHLASGGNDNLVNVWPSAPGEGGWVPLQTFTQHQGAVK 359
+ L GH+ V W+ G + SG D + VW + G V T H V+
Sbjct: 21 IKNLIGHTGGV----WSSQMTGNTVISGSTDRSLKVWNADTG----VCTHTLYGHSSTVR 176
Query: 360 AVAWCPWQSNVLATGGGTSDRHIRIWNVCSGACLSAVDAHSQVCSILWSPHYKELISGHG 419
++ V++ G+ D +R+W++ SG CL+ + H + K ++SG
Sbjct: 177 CLSLSG--KKVVS---GSRDATLRVWDIESGHCLNVLLGHMAAVRCV-QYDGKRVVSG-- 332
Query: 420 FAQNQLV-IWKYPTMAKVAELKGHTSRVLSLTMSPDGATVASAAADETLRLW--RCFEL 475
A + V +W T + + L+GHT+RV SL DG V S + D ++R+W RC +L
Sbjct: 333 -AXDYTVRVWDPDTASCLHTLQGHTNRVYSLQF--DGVYVVSGSLDTSIRVWDVRCGKL 500
Score = 47.8 bits (112), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 51/209 (24%), Positives = 92/209 (44%), Gaps = 4/209 (1%)
Frame = +3
Query: 192 WSS---GN-VLAVALDNSVYLWSASSGDILQLLQMEQPGEYISSVAWIKEGNYLAVGTSS 247
WSS GN V++ + D S+ +W+A +G L S++ G + G+
Sbjct: 54 WSSQMTGNTVISGSTDRSLKVWNADTGVCTHTLYGHSSTVRCLSLS----GKKVVSGSRD 221
Query: 248 AEVQLWDVQQQKRLRNMTSHSARVGSLSWNSYILXXXXXXXXXXXXDVRVAEHHVATLSG 307
A +++WD++ L + H A V + ++ + D A + TL G
Sbjct: 222 ATLRVWDIESGHCLNVLLGHMAAVRCVQYDGKRVVSGAXDYTVRVWDPDTASC-LHTLQG 398
Query: 308 HSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPGEGGWVPLQTFTQHQGAVKAVAWCPWQ 367
H+ V L++ DG ++ SG D + VW G+ + T HQ + +
Sbjct: 399 HTNRVYSLQF--DGVYVVSGSLDTSIRVWDVRCGK----LVHTLMGHQSLTSGL---ELK 551
Query: 368 SNVLATGGGTSDRHIRIWNVCSGACLSAV 396
N+L +G +D +++W+V +G CL +
Sbjct: 552 DNLLVSG--NADSTVKVWDVHTGKCLQTL 632
>17598
Length = 875
Score = 50.1 bits (118), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 42/170 (24%), Positives = 72/170 (42%), Gaps = 3/170 (1%)
Frame = +1
Query: 304 TLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPGEGGWVPLQTFTQHQGAVKAVAW 363
TL GHS V + + D R++ S D + +W G + F H AVA+
Sbjct: 106 TLQGHSHFVSDVSLSADSRYVLSSSWDATLRLWDIKKGN----TTRRFISHTRDALAVAF 273
Query: 364 CPWQSNVLATGGGTSDRHIRIWNVCSGACLSAVDAHSQ---VCSILWSPHYKELISGHGF 420
P + +A+GG D+ ++IWN G C VDA+S V + + K +
Sbjct: 274 SP-DNRQIASGG--RDKALKIWNTV-GECKFTVDANSHQDWVTCVKFHQDAKSPLVVSAS 441
Query: 421 AQNQLVIWKYPTMAKVAELKGHTSRVLSLTMSPDGATVASAAADETLRLW 470
+ +W TM GH +++ ++ ++ +AS + D + W
Sbjct: 442 MDKTIKVWDNQTMTLKHTFVGHKTQINAIDLALKTYYLASGSKDGIVMTW 591
Score = 43.1 bits (100), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 45/220 (20%), Positives = 92/220 (41%), Gaps = 6/220 (2%)
Frame = +1
Query: 228 YISSVAWIKEGNYLAVGTSSAEVQLWDVQQQKRLRNMTSHSARVGSLSW---NSYILXXX 284
++S V+ + Y+ + A ++LWD+++ R SH+ ++++ N I
Sbjct: 127 FVSDVSLSADSRYVLSSSWDATLRLWDIKKGNTTRRFISHTRDALAVAFSPDNRQIASGG 306
Query: 285 XXXXXXXXXDVRVAEHHVATLSGHSQEVCGLRWAPDGRH--LASGGNDNLVNVWPSAPGE 342
V + V S H V +++ D + + S D + VW +
Sbjct: 307 RDKALKIWNTVGECKFTVDANS-HQDWVTCVKFHQDAKSPLVVSASMDKTIKVWDNQT-- 477
Query: 343 GGWVPLQ-TFTQHQGAVKAVAWCPWQSNVLATGGGTSDRHIRIWNVCSGACLSAVDAHSQ 401
+ L+ TF H+ + A+ ++ LA+ G+ D + WN+ +G L +D +
Sbjct: 478 ---MTLKHTFVGHKTQINAID-LALKTYYLAS--GSKDGIVMTWNIQNGTFLGKIDCDCE 639
Query: 402 VCSILWSPHYKELISGHGFAQNQLVIWKYPTMAKVAELKG 441
V ++ +SP+ L G + IW P K+ +++
Sbjct: 640 VNAVKFSPNKYWLFVG---TSEGIQIWDLPNQKKIKDIRA 750
Score = 37.0 bits (84), Expect = 0.019, Method: Compositional matrix adjust.
Identities = 39/157 (24%), Positives = 67/157 (42%), Gaps = 10/157 (6%)
Frame = +1
Query: 324 LASGGNDNLVNVWPSAPGEGG-----W-VPLQTFTQHQGAVKAVAWCPWQSNVLATGGGT 377
L GG D L+ VW P + G W P +T H V V+ VL++ +
Sbjct: 10 LIXGGRDKLLIVWDLVPRKDGDEDETWGGPRRTLQGHSHFVSDVSLSADSRYVLSS---S 180
Query: 378 SDRHIRIWNVCSGACLSAVDAHSQ-VCSILWSPHYKELISGHGFAQNQLVIWKYPTMAKV 436
D +R+W++ G +H++ ++ +SP +++ SG L IW K
Sbjct: 181 WDATLRLWDIKKGNTTRRFISHTRDALAVAFSPDNRQIASGG--RDKALKIWNTVGECKF 354
Query: 437 -AELKGHTSRVLSLTMSPDGAT--VASAAADETLRLW 470
+ H V + D + V SA+ D+T+++W
Sbjct: 355 TVDANSHQDWVTCVKFHQDAKSPLVVSASMDKTIKVW 465
>00561
Length = 1003
Score = 40.8 bits (94), Expect(2) = 4e-06, Method: Compositional matrix adjust.
Identities = 45/198 (22%), Positives = 80/198 (40%), Gaps = 5/198 (2%)
Frame = -3
Query: 227 EYISSVAWIKEGNYLAVGTSSAEVQLWDVQQQKRLRNMTSHSARVGSLSW---NSYILXX 283
+IS V +GNY G+ ++LWD+ K R H+ V S+++ N I+
Sbjct: 863 HFISDVVLSSDGNYALSGSWDQTLRLWDLAAGKTTRRFEGHTKDVLSVAFSADNRQIVSG 684
Query: 284 XXXXXXXXXXDVRVAEHHVATLSGHSQEVCGLRWAPDGRH--LASGGNDNLVNVWPSAPG 341
+ + + GH+ V +R++P+ + + S G D V VW A
Sbjct: 683 SRDKTIKLWNTLAECKFTIQE-DGHTDWVSCVRFSPNHSNPIIVSCGWDRTVKVWNLANC 507
Query: 342 EGGWVPLQTFTQHQGAVKAVAWCPWQSNVLATGGGTSDRHIRIWNVCSGACLSAVDAHSQ 401
+ H G + V P L T GG D +W++ G L ++ +
Sbjct: 506 KLK----NNHHGHNGYLNTVTVSP--DGSLCTSGG-KDSKALLWDLNDGKNLYTLEHNDI 348
Query: 402 VCSILWSPHYKELISGHG 419
+ ++ +SP+ L +G
Sbjct: 347 INALCFSPNRYWLCVAYG 294
Score = 27.7 bits (60), Expect(2) = 4e-06, Method: Compositional matrix adjust.
Identities = 12/32 (37%), Positives = 19/32 (59%)
Frame = -2
Query: 440 KGHTSRVLSLTMSPDGATVASAAADETLRLWR 471
K + LSL S DG T+ + +D T+R+W+
Sbjct: 216 KAEQPQCLSLAWSTDGQTLFAGYSDNTIRVWQ 121
Score = 48.9 bits (115), Expect = 5e-06, Method: Compositional matrix adjust.
Identities = 43/170 (25%), Positives = 75/170 (44%), Gaps = 4/170 (2%)
Frame = -3
Query: 305 LSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPGEGGWVPLQTFTQHQGAVKAVAWC 364
L GHS + + + DG + SG D + +W A G+ + F H V +VA+
Sbjct: 878 LYGHSHFISDVVLSSDGNYALSGSWDQTLRLWDLAAGKT----TRRFEGHTKDVLSVAFS 711
Query: 365 PWQSNVLATGGGTSDRHIRIWNVCSGACLSAV--DAHSQ-VCSILWSP-HYKELISGHGF 420
+++ G+ D+ I++WN + C + D H+ V + +SP H +I G+
Sbjct: 710 ADNRQIVS---GSRDKTIKLWNTLA-ECKFTIQEDGHTDWVSCVRFSPNHSNPIIVSCGW 543
Query: 421 AQNQLVIWKYPTMAKVAELKGHTSRVLSLTMSPDGATVASAAADETLRLW 470
+ + +W GH + ++T+SPDG+ S D LW
Sbjct: 542 DRT-VKVWNLANCKLKNNHHGHNGYLNTVTVSPDGSLCTSGGKDSKALLW 396
Score = 30.4 bits (67), Expect = 1.9, Method: Compositional matrix adjust.
Identities = 18/56 (32%), Positives = 26/56 (46%), Gaps = 10/56 (17%)
Frame = -3
Query: 425 LVIWK----------YPTMAKVAELKGHTSRVLSLTMSPDGATVASAAADETLRLW 470
L++WK YP L GH+ + + +S DG S + D+TLRLW
Sbjct: 938 LIVWKLTRDEDTNYGYPQ----KRLYGHSHFISDVVLSSDGNYALSGSWDQTLRLW 783
>01327
Length = 2215
Score = 47.8 bits (112), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 43/186 (23%), Positives = 72/186 (38%), Gaps = 8/186 (4%)
Frame = +3
Query: 296 RVAEHHVATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPGEGGWVPLQTFTQHQ 355
R H + GH V + D L SG DN V +W G L+ Q
Sbjct: 252 RGNSHSIRDFIGHDMVVTAIHLNTDNTLLCSGSRDNTVRIWDVETG----ACLRQNNIPQ 419
Query: 356 GAVKAVAWCPWQSNVLATGGGTSDRHIRIWNVCSGACLSAVDAHSQV---CSILWSPHYK 412
V V W P ++ G D+ +RI++ + + + + C + +
Sbjct: 420 NLVTDVKWLPGSHLIIQAG---EDKEVRIYDSRTLGIVRSFTKKQYIQMSCDVTADGQFC 590
Query: 413 ELISGHGFAQN--QLVIWKYPTMAKVAELKGHTSRV---LSLTMSPDGATVASAAADETL 467
L +GF N + +W+ + E KGH + L L + D +A+A+ D ++
Sbjct: 591 -LTCSNGFGGNGCEATLWQLSDGSIQNEFKGHREAIEACLFLPSNQDMTLIATASRDCSV 767
Query: 468 RLWRCF 473
R+W F
Sbjct: 768 RVWNMF 785
Score = 29.3 bits (64), Expect = 4.3, Method: Compositional matrix adjust.
Identities = 15/74 (20%), Positives = 33/74 (44%), Gaps = 10/74 (13%)
Frame = +3
Query: 407 WSPHYKELIS-GHGFAQNQLV---------IWKYPTMAKVAELKGHTSRVLSLTMSPDGA 456
W+ H +E+ +G + N + +W+ + + GH V ++ ++ D
Sbjct: 153 WTGHDREITKVCYGASCNGMFSASRDKTIKMWQRGNSHSIRDFIGHDMVVTAIHLNTDNT 332
Query: 457 TVASAAADETLRLW 470
+ S + D T+R+W
Sbjct: 333 LLCSGSRDNTVRIW 374
>03156
Length = 1014
Score = 47.4 bits (111), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 42/186 (22%), Positives = 71/186 (38%), Gaps = 8/186 (4%)
Frame = +1
Query: 296 RVAEHHVATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPGEGGWVPLQTFTQHQ 355
R H + GH V + D L SG DN V +W G L+ Q
Sbjct: 142 RGNSHSIRDFIGHDMVVTAIHLNTDNTLLCSGSRDNTVRIWDVETG----ACLRQNNIPQ 309
Query: 356 GAVKAVAWCPWQSNVLATGGGTSDRHIRIWNVCSGACLSAVDAHSQV---CSILWSPHYK 412
V V W P ++ G D+ +RI++ + + + + C + +
Sbjct: 310 NLVTDVKWLPGSHLIIQAG---EDKEVRIYDSRTLGIVRSFTKKQYIQMSCDVTADGQFC 480
Query: 413 ELISGHGFAQN--QLVIWKYPTMAKVAELKGHTSRVLSLTMSP---DGATVASAAADETL 467
L +GF N + +W+ + E KGH + + P D +A+A+ D ++
Sbjct: 481 -LTCSNGFGGNGCEATLWQLSDGSIQNEFKGHREAIEACLFLPSNQDMTLIATASRDCSV 657
Query: 468 RLWRCF 473
R+W F
Sbjct: 658 RVWNMF 675
Score = 28.9 bits (63), Expect = 5.4, Method: Compositional matrix adjust.
Identities = 15/74 (20%), Positives = 33/74 (44%), Gaps = 10/74 (13%)
Frame = +1
Query: 407 WSPHYKELIS-GHGFAQNQLV---------IWKYPTMAKVAELKGHTSRVLSLTMSPDGA 456
W+ H +E+ +G + N + +W+ + + GH V ++ ++ D
Sbjct: 43 WTGHDREITKVCYGASCNGMFSASRDKTIKMWQRGNSHSIRDFIGHDMVVTAIHLNTDNT 222
Query: 457 TVASAAADETLRLW 470
+ S + D T+R+W
Sbjct: 223 LLCSGSRDNTVRIW 264
>12806
Length = 961
Score = 47.0 bits (110), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 45/157 (28%), Positives = 74/157 (47%), Gaps = 10/157 (6%)
Frame = +3
Query: 324 LASGGNDNLVNVWPSAPGEGG-----W-VPLQTFTQHQGAVKAVAWCPWQSNVLATGGGT 377
L SGG DN + VW P + G W VP +T T H + +A L++ +
Sbjct: 54 LISGGRDNNIIVWDL*PKKDGDEDQTWGVPRKTLTGHSHFISDLALSADSRFALSS---S 224
Query: 378 SDRHIRIWNVCSGACLSAVDAHSQ-VCSILWSPHYKELISGHGFAQNQLVIWKYPTMAK- 435
D +R+W++ G+ S H++ V ++ +SP +++ SG G +N L IW K
Sbjct: 225 WDATLRLWDIKKGSTTSRFINHTRDVLTVAFSPDNRQIASG-GRDKN-LKIWNIMGECKY 398
Query: 436 VAELKGHTSRVLSLTMSPDGAT--VASAAADETLRLW 470
+ HT V + D V SA+ D+T+++W
Sbjct: 399 TVDANAHTDWVTCVRFHQDTKNPIVVSASNDKTIKVW 509
Score = 45.1 bits (105), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 43/219 (19%), Positives = 92/219 (42%), Gaps = 5/219 (2%)
Frame = +3
Query: 228 YISSVAWIKEGNYLAVGTSSAEVQLWDVQQQKRLRNMTSHSARVGSLSW--NSYILXXXX 285
+IS +A + + + A ++LWD+++ +H+ V ++++ ++ +
Sbjct: 171 FISDLALSADSRFALSSSWDATLRLWDIKKGSTTSRFINHTRDVLTVAFSPDNRQIASGG 350
Query: 286 XXXXXXXXDVRVAEHHVATLSGHSQEVCGLRWAPDGRH--LASGGNDNLVNVWPSAPGEG 343
++ + + H+ V +R+ D ++ + S ND + VW +
Sbjct: 351 RDKNLKIWNIMGECKYTVDANAHTDWVTCVRFHQDTKNPIVVSASNDKTIKVWDNHT--- 521
Query: 344 GWVPLQTFTQHQGAVKAVAWCPWQSNVLATGGGTSDRHIRIWNVCSGACLSAVDAHSQVC 403
TF H+ + A+ +N L +G + D WNV G+ + +D Q+
Sbjct: 522 -MTLKNTFVGHKAQITAL---DMSTNYLVSG--SKDGIAMTWNVAEGSFVGKIDCDDQIN 683
Query: 404 SILWS-PHYKELISGHGFAQNQLVIWKYPTMAKVAELKG 441
+I ++ + K+ + QN + IW Y K+ ELK
Sbjct: 684 AIKFNIENNKKKVWLFIGTQNGIQIWDYSGEKKIKELKA 800
>16105
Length = 960
Score = 45.8 bits (107), Expect = 4e-05, Method: Compositional matrix adjust.
Identities = 27/124 (21%), Positives = 57/124 (45%), Gaps = 8/124 (6%)
Frame = -2
Query: 354 HQGAVKAVAWCPWQSNVLATGGGTSDRHIRIWNV--------CSGACLSAVDAHSQVCSI 405
H+GAV + WCP NV+A+ + D +++W + + + V + C I
Sbjct: 578 HKGAVLDIQWCPHNDNVIAS--ASDDCTVKVWQIPDSGLVTNLTDPVVDLVGHQKRCCLI 405
Query: 406 LWSPHYKELISGHGFAQNQLVIWKYPTMAKVAELKGHTSRVLSLTMSPDGATVASAAADE 465
+W P + ++ G A N+++ W T + E+ + ++ + +G+ + D+
Sbjct: 404 VWHPSAQNVLVSAG-ADNKILFWNVGTGEPMLEVD-VPDMIYCMSFNFNGSRLVCTCKDK 231
Query: 466 TLRL 469
LR+
Sbjct: 230 KLRI 219
Score = 40.8 bits (94), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 30/103 (29%), Positives = 44/103 (42%), Gaps = 5/103 (4%)
Frame = -2
Query: 305 LSGHSQEVCGLRWAPDGRH-LASGGNDNLVNVWPSAPGEGGWV----PLQTFTQHQGAVK 359
++GH V ++W P + +AS +D V VW P G P+ HQ
Sbjct: 587 VAGHKGAVLDIQWCPHNDNVIASASDDCTVKVW-QIPDSGLVTNLTDPVVDLVGHQKRCC 411
Query: 360 AVAWCPWQSNVLATGGGTSDRHIRIWNVCSGACLSAVDAHSQV 402
+ W P NVL + G +D I WNV +G + VD +
Sbjct: 410 LIVWHPSAQNVLVSAG--ADNKILFWNVGTGEPMLEVDVPDMI 288
Score = 30.4 bits (67), Expect = 1.5, Method: Compositional matrix adjust.
Identities = 15/42 (35%), Positives = 20/42 (47%), Gaps = 1/42 (2%)
Frame = -2
Query: 302 VATLSGHSQEVCGLRWAPDGRH-LASGGNDNLVNVWPSAPGE 342
V L GH + C + W P ++ L S G DN + W GE
Sbjct: 446 VVDLVGHQKRCCLIVWHPSAQNVLVSAGADNKILFWNVGTGE 321
>01768
Length = 1424
Score = 45.8 bits (107), Expect = 4e-05, Method: Compositional matrix adjust.
Identities = 28/83 (33%), Positives = 42/83 (50%), Gaps = 2/83 (2%)
Frame = +3
Query: 307 GHSQEVCGLRWAPDGRH-LASGGNDNLVNVWPSAPGEGGWVPLQ-TFTQHQGAVKAVAWC 364
HS+++ + W P +H LASGG+D ++ +W V Q +F H V ++ W
Sbjct: 972 AHSRDINVINWNPIEKHLLASGGDDGIIKIWDLRMFRNKPVSAQASFKLHSQPVTSLEWN 1151
Query: 365 PWQSNVLATGGGTSDRHIRIWNV 387
P S+VLA G D I IW+
Sbjct: 1152 PQDSSVLAASG--EDDQITIWDF 1214
>01805
Length = 2124
Score = 44.7 bits (104), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 40/170 (23%), Positives = 74/170 (43%), Gaps = 3/170 (1%)
Frame = -1
Query: 304 TLSGHSQEVCGLRWAPDGRH-LASGGNDNLVNVWPSAPGEGGWVPLQTFTQHQGAVKAVA 362
+++GH+Q V L W + RH LAS D V +W + G+ FTQH V+
Sbjct: 591 SVTGHTQAVLDLSWNRNARHVLASASADTTVALWDLSEGKMA----MNFTQHSREVQCCN 424
Query: 363 WCPWQSNVLATGGGTSDRHIRIWNVCSG-ACLSAVDAHSQVCSILWSPHYKELISGHGFA 421
W P + L T G+ D +++ + S C + +V +W+ H+ L
Sbjct: 423 WHPQEEQTLLT--GSFDNTVKVVDCRSAETCHKSWTVEGEVEKAVWN-HHNPLQLLACTD 253
Query: 422 QNQLVIWKYPTMAKVAELKGHTSRVLSLTMSPD-GATVASAAADETLRLW 470
+ + + V + H+S V + +S + + + D+T+++W
Sbjct: 252 KGMVYCFDIRHEKPVFSVGAHSSCVTGVCLSSQIPGLMITTSEDKTMKVW 103
Score = 29.3 bits (64), Expect = 3.7, Method: Compositional matrix adjust.
Identities = 13/37 (35%), Positives = 19/37 (51%)
Frame = -1
Query: 241 LAVGTSSAEVQLWDVQQQKRLRNMTSHSARVGSLSWN 277
LA ++ V LWD+ + K N T HS V +W+
Sbjct: 528 LASASADTTVALWDLSEGKMAMNFTQHSREVQCCNWH 418
>27465
Length = 658
Score = 43.1 bits (100), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 36/176 (20%), Positives = 63/176 (35%), Gaps = 4/176 (2%)
Frame = -1
Query: 299 EHHV---ATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPGEGGWVPLQTFTQHQ 355
+HH L H + + + G +G D +W +A E L T H+
Sbjct: 400 DHHFYLFKVLRAHILPLTNVAFNKSGSSFITGSYDRTCKIWDTASAE----ELHTLEGHR 233
Query: 356 GAVKAVAWC-PWQSNVLATGGGTSDRHIRIWNVCSGACLSAVDAHSQVCSILWSPHYKEL 414
V A+A+ P+ V+ G+ D+ ++W+ G C
Sbjct: 232 NVVYAIAFNNPFGDKVIT---GSFDKTCKLWSTADGKC---------------------- 128
Query: 415 ISGHGFAQNQLVIWKYPTMAKVAELKGHTSRVLSLTMSPDGATVASAAADETLRLW 470
Y T L+GHT+ ++ ++ +P +A+ + D T RLW
Sbjct: 127 ---------------YHT------LRGHTAEIVCVSFNPSSTLIATGSMDTTCRLW 23
Score = 36.6 bits (83), Expect = 0.021, Method: Compositional matrix adjust.
Identities = 42/183 (22%), Positives = 68/183 (37%), Gaps = 13/183 (7%)
Frame = -1
Query: 91 ASFLLSKENQPENSQTPTKKEHQKAWAL-----------NLNGFDVEEAKILRLSGKPQN 139
A ++ + + E TP+K+EH K W + F V A IL L+ N
Sbjct: 511 ADLVVQEIAEKEQLITPSKQEHVKNWCFACRKTRPKDDHHFYLFKVLRAHILPLTNVAFN 332
Query: 140 APEGYQNRLKVLYSQKATPGSSRKTCRYIPSLPDRILDAPE-IRNDYYLNLVDWSSGN-V 197
GS +TC+ + L E RN Y + G+ V
Sbjct: 331 KS-----------GSSFITGSYDRTCKIWDTASAEELHTLEGHRNVVYAIAFNNPFGDKV 185
Query: 198 LAVALDNSVYLWSASSGDILQLLQMEQPGEYISSVAWIKEGNYLAVGTSSAEVQLWDVQQ 257
+ + D + LWS + G L+ I V++ +A G+ +LWDV++
Sbjct: 184 ITGSFDKTCKLWSTADGKCYHTLRGHTAE--IVCVSFNPSSTLIATGSMDTTCRLWDVEK 11
Query: 258 QKR 260
+R
Sbjct: 10 AQR 2
>15780
Length = 735
Score = 42.0 bits (97), Expect = 6e-04, Method: Compositional matrix adjust.
Identities = 18/50 (36%), Positives = 27/50 (54%)
Frame = -1
Query: 421 AQNQLVIWKYPTMAKVAELKGHTSRVLSLTMSPDGATVASAAADETLRLW 470
A + +++W + VA L HT V +L S DG +AS D ++RLW
Sbjct: 714 ADHTVIVWDIASGTAVAHLTAHTDTVYALCFSRDGTVLASGGMDNSIRLW 565
Score = 28.5 bits (62), Expect = 5.9, Method: Compositional matrix adjust.
Identities = 19/76 (25%), Positives = 37/76 (48%)
Frame = -1
Query: 203 DNSVYLWSASSGDILQLLQMEQPGEYISSVAWIKEGNYLAVGTSSAEVQLWDVQQQKRLR 262
D++V +W +SG + L Y ++ + ++G LA G ++LWD+ + +
Sbjct: 711 DHTVIVWDIASGTAVAHLTAHTDTVY--ALCFSRDGTVLASGGMDNSIRLWDLARVMEEQ 538
Query: 263 NMTSHSARVGSLSWNS 278
+ + S SLS N+
Sbjct: 537 DPETDSNVPSSLSVNT 490
>13278
Length = 870
Score = 41.6 bits (96), Expect = 7e-04, Method: Compositional matrix adjust.
Identities = 30/109 (27%), Positives = 53/109 (48%), Gaps = 9/109 (8%)
Frame = +1
Query: 309 SQEVCGLRWAPDG---------RHLASGGNDNLVNVWPSAPGEGGWVPLQTFTQHQGAVK 359
++E+ ++W+P G LAS D+ V +W G + L T T+HQ V
Sbjct: 49 TKEIYTIKWSPTGPGTSNPNTSLILASASFDSTVRLWEVERG----LCLHTLTKHQEPVY 216
Query: 360 AVAWCPWQSNVLATGGGTSDRHIRIWNVCSGACLSAVDAHSQVCSILWS 408
+VA+ P LA+G + D+ + IWNV +G+ + + + + W+
Sbjct: 217 SVAFSP-DGKYLASG--SFDKCVHIWNVQTGSLVHSYKGTGGIFEVCWN 354
Score = 37.4 bits (85), Expect = 0.013, Method: Compositional matrix adjust.
Identities = 26/82 (31%), Positives = 40/82 (48%), Gaps = 1/82 (1%)
Frame = +1
Query: 197 VLAVA-LDNSVYLWSASSGDILQLLQMEQPGEYISSVAWIKEGNYLAVGTSSAEVQLWDV 255
+LA A D++V LW G L L Q E + SVA+ +G YLA G+ V +W+V
Sbjct: 118 ILASASFDSTVRLWEVERGLCLHTLTKHQ--EPVYSVAFSPDGKYLASGSFDKCVHIWNV 291
Query: 256 QQQKRLRNMTSHSARVGSLSWN 277
Q + + + + + WN
Sbjct: 292 QTGSLVHSYKG-TGGIFEVCWN 354
Score = 35.4 bits (80), Expect = 0.058, Method: Compositional matrix adjust.
Identities = 15/38 (39%), Positives = 24/38 (63%)
Frame = +1
Query: 304 TLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPG 341
TL+ H + V + ++PDG++LASG D V++W G
Sbjct: 187 TLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNVQTG 300
Score = 32.0 bits (71), Expect = 0.61, Method: Compositional matrix adjust.
Identities = 22/95 (23%), Positives = 42/95 (44%), Gaps = 8/95 (8%)
Frame = +1
Query: 384 IWNVCSGACLSAVDAHS-QVCSILWSPH-------YKELISGHGFAQNQLVIWKYPTMAK 435
IW++ +C+ + + ++ +I WSP LI + + +W+
Sbjct: 1 IWSMGKDSCIHDLQLTTKEIYTIKWSPTGPGTSNPNTSLILASASFDSTVRLWEVERGLC 180
Query: 436 VAELKGHTSRVLSLTMSPDGATVASAAADETLRLW 470
+ L H V S+ SPDG +AS + D+ + +W
Sbjct: 181 LHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIW 285
>19140
Length = 573
Score = 38.9 bits (89), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 17/39 (43%), Positives = 25/39 (64%)
Frame = -3
Query: 432 TMAKVAELKGHTSRVLSLTMSPDGATVASAAADETLRLW 470
T K+ +LKGHT V +L ++ DG S ++D T+RLW
Sbjct: 520 TCHKLMKLKGHTDNVKALVLNRDGTQCLSGSSDGTIRLW 404
>10264
Length = 416
Score = 38.9 bits (89), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 23/81 (28%), Positives = 39/81 (48%), Gaps = 2/81 (2%)
Frame = -1
Query: 393 LSAVDAHSQ-VCSILWSPHYKELISGHGFAQNQLVIWKYPTMAKVAELKGHTSRVLSLTM 451
L + HSQ V + WSPH+ + G+ + +W +A+ KGH R+L+
Sbjct: 266 LRELSGHSQRVTDMSWSPHHDARLVSVGY-DAEAFVWDVQKGTALAQFKGHMGRLLTCQF 90
Query: 452 SP-DGATVASAAADETLRLWR 471
S D V + +D ++ +WR
Sbjct: 89 SGLDPDLVMTGGSDASVHVWR 27
Score = 38.5 bits (88), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 29/85 (34%), Positives = 38/85 (44%), Gaps = 2/85 (2%)
Frame = -1
Query: 305 LSGHSQEVCGLRWAP--DGRHLASGGNDNLVNVWPSAPGEGGWVPLQTFTQHQGAVKAVA 362
LSGHSQ V + W+P D R L S G D VW G L F H G +
Sbjct: 257 LSGHSQRVTDMSWSPHHDAR-LVSVGYDAEAFVWDVQKG----TALAQFKGHMGRLLTCQ 93
Query: 363 WCPWQSNVLATGGGTSDRHIRIWNV 387
+ +++ TGG SD + +W V
Sbjct: 92 FSGLDPDLVMTGG--SDASVHVWRV 24
>01598
Length = 1545
Score = 38.9 bits (89), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 24/81 (29%), Positives = 38/81 (46%), Gaps = 2/81 (2%)
Frame = +1
Query: 393 LSAVDAHSQ-VCSILWSPHYKELISGHGFAQNQLVIWKYPTMAKVAELKGHTSRVLSLTM 451
L + HSQ V + WSPH+ + G+ V W +A+ KGH R+L+
Sbjct: 1279 LRELSGHSQRVTDMSWSPHHDARLVSVGYDAEAFV-WDVQKGTALAQFKGHMGRLLTCQF 1455
Query: 452 SP-DGATVASAAADETLRLWR 471
S D V + +D ++ +WR
Sbjct: 1456 SGLDPDLVMTGGSDASVHVWR 1518
Score = 38.5 bits (88), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 29/85 (34%), Positives = 38/85 (44%), Gaps = 2/85 (2%)
Frame = +1
Query: 305 LSGHSQEVCGLRWAP--DGRHLASGGNDNLVNVWPSAPGEGGWVPLQTFTQHQGAVKAVA 362
LSGHSQ V + W+P D R L S G D VW G L F H G +
Sbjct: 1288 LSGHSQRVTDMSWSPHHDAR-LVSVGYDAEAFVWDVQKG----TALAQFKGHMGRLLTCQ 1452
Query: 363 WCPWQSNVLATGGGTSDRHIRIWNV 387
+ +++ TGG SD + +W V
Sbjct: 1453 FSGLDPDLVMTGG--SDASVHVWRV 1521
>11493
Length = 535
Score = 38.9 bits (89), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 43/172 (25%), Positives = 73/172 (42%), Gaps = 4/172 (2%)
Frame = -2
Query: 301 HVATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWP-SAPGEGGWVPLQTFTQHQGAVK 359
+ TLS H + VC + + +++ +GG V VW S PG V Q ++
Sbjct: 498 QINTLS-HGEVVCAVTISNPTKYVYTGGK-GCVKVWDISQPGNKNPVSQLDCLQRDNYIR 325
Query: 360 AVAWCPWQSNVLATGGGTSDRHIRIWNVCSGA--CLSAVDAHSQVCSIL-WSPHYKELIS 416
+V P L GG S+ + IW++ S + + + + C L SP K S
Sbjct: 324 SVKLLP-DGRTLIVGGEASN--LSIWDLASPTPRIKAELTSAAPACYALAISPDSKVCFS 154
Query: 417 GHGFAQNQLVIWKYPTMAKVAELKGHTSRVLSLTMSPDGATVASAAADETLR 468
+ + +W V + +GHT + +SPDG+ + + D T+R
Sbjct: 153 C--CSDGNIAVWDLHNEILVRQFQGHTDGASCIDISPDGSRLWTGGLDNTVR 4
Score = 28.1 bits (61), Expect = 8.9, Method: Compositional matrix adjust.
Identities = 23/69 (33%), Positives = 30/69 (43%), Gaps = 2/69 (2%)
Frame = -2
Query: 404 SILWSPHYKELISGHGFAQNQLVIWKY--PTMAKVAELKGHTSRVLSLTMSPDGATVASA 461
S+ P + LI G G A N L IW PT AEL +L +SPD S
Sbjct: 324 SVKLLPDGRTLIVG-GEASN-LSIWDLASPTPRIKAELTSAAPACYALAISPDSKVCFSC 151
Query: 462 AADETLRLW 470
+D + +W
Sbjct: 150 CSDGNIAVW 124
>31474
Length = 403
Score = 38.5 bits (88), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 32/112 (28%), Positives = 55/112 (49%), Gaps = 5/112 (4%)
Frame = -3
Query: 302 VATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPGEG-GWVPLQTFTQ-HQGAVK 359
V LS H + + W P G LAS G+D ++ +W EG WV T T H V+
Sbjct: 326 VCCLSAHDEHAWCVAWNPTGTLLASCGSDKIIKIWGK---EGDNWVCKSTLTDAHTRTVR 156
Query: 360 AVAWCPWQSNVLATGGGTSDRHIRIWNVCSG--ACLSAVDAH-SQVCSILWS 408
++ W P N L++ + D +W+ G C++ ++ H ++V ++ W+
Sbjct: 155 SLGWSP-CGNYLSS--ASFDATTAVWSRKGGEFECIATLEGHENEVKAVAWA 9
>01249
Length = 1743
Score = 38.5 bits (88), Expect = 0.007, Method: Compositional matrix adjust.
Identities = 57/284 (20%), Positives = 98/284 (34%), Gaps = 2/284 (0%)
Frame = -1
Query: 189 LVDWSSGNVLAVALDNSVYLWSASSGDILQLLQMEQPGEYISSVAWIKEGNYLAVGTSSA 248
LV G ++ +Y+W + G ++ LL + + + +G+ V TSS
Sbjct: 1473 LVVSPDGLFCLASISEKIYIWEMTGGSLVGLLSDFNEA---TKIQFTDDGSQFVVATSSG 1303
Query: 249 EVQLWDVQQQKRLRNMTSHSARVGSLSWNSYILXXXXXXXXXXXXDVRVAEHHVATLSGH 308
+ +WD R +T+ S R L T++ H
Sbjct: 1302 HLNIWDFA-----RVVTTTSQRARGLKPGR-------------------------TINAH 1213
Query: 309 SQEVCGLRWAPDG--RHLASGGNDNLVNVWPSAPGEGGWVPLQTFTQHQGAVKAVAWCPW 366
S+ + GL G +AS +D +W G L+T G
Sbjct: 1212 SEPITGLHVGCGGPAARVASSSSDGTCKLWDMLSG----ALLRTMVYETGV--GCLIMDK 1051
Query: 367 QSNVLATGGGTSDRHIRIWNVCSGACLSAVDAHSQVCSILWSPHYKELISGHGFAQNQLV 426
Q + L G D IL SP + ++ +Q+++
Sbjct: 1050 QEHFLLAGLDNGD-------------------------ILCSPLFGQI------SQSEVF 964
Query: 427 IWKYPTMAKVAELKGHTSRVLSLTMSPDGATVASAAADETLRLW 470
+ K+ T A L+GH+ V L S DG +AS + + + +W
Sbjct: 963 VSKHTTKAGERVLQGHSDAVTCLAFSSDGQRLASGSQNGKVIIW 832
Score = 33.1 bits (74), Expect = 0.27, Method: Compositional matrix adjust.
Identities = 30/117 (25%), Positives = 47/117 (40%), Gaps = 15/117 (12%)
Frame = -1
Query: 241 LAVGTSSAEVQLWDVQQQKRLRNMTSHSARVGSLSWNS---YILXXXXXXX--------X 289
+A +S +LWD+ LR M + VG L + ++L
Sbjct: 1161 VASSSSDGTCKLWDMLSGALLRTMV-YETGVGCLIMDKQEHFLLAGLDNGDILCSPLFGQ 985
Query: 290 XXXXDVRVAEHHVA----TLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPGE 342
+V V++H L GHS V L ++ DG+ LASG + V +W G+
Sbjct: 984 ISQSEVFVSKHTTKAGERVLQGHSDAVTCLAFSSDGQRLASGSQNGKVIIWNMESGD 814
>02960
Length = 1577
Score = 38.1 bits (87), Expect = 0.009, Method: Compositional matrix adjust.
Identities = 44/156 (28%), Positives = 74/156 (47%), Gaps = 5/156 (3%)
Frame = +2
Query: 302 VATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPGEGGWVPLQTFTQHQGAVKAV 361
V TLSGH++ V +RW D + + D+ + +W + + Q AV V
Sbjct: 938 VLTLSGHAEAVSAVRWL-DPHRVVTSSWDHSLRLWDLHTAQQ-----TSLIQGSKAVLDV 1099
Query: 362 AWCPWQSNVLATGGGTSDRHIRIWN-VCS--GACLSAVDAHSQ-VCSILWSPHYKELISG 417
A+ P S++L T G++DRH+R+ + CS A +H+ V + WSP + L
Sbjct: 1100 AYSP-LSHMLIT--GSADRHVRLVDPRCSEGETVKCAFTSHTGWVTGVDWSPTREHLFLS 1270
Query: 418 HGFAQNQLVIWKYPT-MAKVAELKGHTSRVLSLTMS 452
G N L +W + A + ++ H R+L++ S
Sbjct: 1271 -GSYDNVLKLWDTRSPKATLYDMNWHEDRILAVDWS 1375
Score = 37.7 bits (86), Expect = 0.010, Method: Compositional matrix adjust.
Identities = 66/303 (21%), Positives = 107/303 (35%), Gaps = 26/303 (8%)
Frame = +2
Query: 194 SGNVLAVALDNSVYLWSASSGDILQLLQMEQPGEYISSVAWIKEGNYLAVGT--SSAEVQ 251
+G L+ + DN+V LWS I+ + P + VAWIK V T + + Q
Sbjct: 515 TGXXLSGSYDNTVRLWSTKGEAIMTIPGHTSP---VKCVAWIKHDESSGVSTFVTGSHDQ 685
Query: 252 LWDVQQQKRLRNMTSHSARVGSLSWNSYILXXXXXXXXXXXXDVRVAEHHVATLSGHSQE 311
V Q +R N D R++ GH+
Sbjct: 686 TALVWQWQRETN----------------------------EVDCRLS------CRGHAAS 763
Query: 312 VCGLRWAPDGRHLASGGNDNLVNVWPSAPGEGG----------------------WVPLQ 349
V + +PD + + +G D ++ +W + G VP+
Sbjct: 764 VDCVAVSPDSQQMCTGSWDKMLKLWSTDCNVDGDQSEDTERPSKKKKSAKSTTQTRVPVL 943
Query: 350 TFTQHQGAVKAVAWCPWQSNVLATGGGTSDRHIRIWNVCSGACLSAVDAHSQVCSILWSP 409
T + H AV AV W V ++ D +R+W++ + S + V + +SP
Sbjct: 944 TLSGHAEAVSAVRWLDPHRVVTSSW----DHSLRLWDLHTAQQTSLIQGSKAVLDVAYSP 1111
Query: 410 HYKELISGHGFAQNQLVIWKYPTMAKV-AELKGHTSRVLSLTMSPDGATV-ASAAADETL 467
LI+G +LV + V HT V + SP + S + D L
Sbjct: 1112LSHMLITGSADRHVRLVDPRCSEGETVKCAFTSHTGWVTGVDWSPTREHLFLSGSYDNVL 1291
Query: 468 RLW 470
+LW
Sbjct: 1292KLW 1300
>17602
Length = 481
Score = 37.7 bits (86), Expect = 0.011, Method: Composition-based stats.
Identities = 33/159 (20%), Positives = 71/159 (44%), Gaps = 8/159 (5%)
Frame = +3
Query: 251 QLWDVQQQKRLRNMTSHSARVGSLSWN--SYILXXXXXXXXXXXXDVRVAEHHVATLSGH 308
++WDV+ K L+ + +HS V ++ +N ++ D + +
Sbjct: 3 RIWDVKTGKCLKTLPAHSDPVTAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLXTLIDDD 182
Query: 309 SQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPGEGGWVPLQTFTQHQGAVKAVAWCPWQS 368
+ V ++++P+G+++ + DN + +W + G+ L+T+ H+ +C + +
Sbjct: 183 NPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKC----LKTYVGHRNE----KYCIF-A 335
Query: 369 NVLATGG-----GTSDRHIRIWNVC-SGACLSAVDAHSQ 401
N TGG G+ D + IWN+ G A +H +
Sbjct: 336 NFSVTGGKWIVSGSEDNMVYIWNLLDQGDSTEATGSHRR 452
Score = 34.7 bits (78), Expect = 0.083, Method: Composition-based stats.
Identities = 25/89 (28%), Positives = 39/89 (43%), Gaps = 1/89 (1%)
Frame = +3
Query: 383 RIWNVCSGACLSAVDAHSQVCSILWSPHYKELISGHGFAQNQLVIWKYPTMAKVAELKGH 442
RIW+V +G CL + AHS + + LI + IW + + L
Sbjct: 3 RIWDVKTGKCLKTLPAHSDPVTAVHFNRDGSLIVSSSY-DGLCRIWDTASGQCLXTLIDD 179
Query: 443 TSRVLSLT-MSPDGATVASAAADETLRLW 470
+ +S SP+G + +A D TL+LW
Sbjct: 180 DNPPVSFVKFSPNGKYILAATLDNTLKLW 266
Score = 30.8 bits (68), Expect = 1.5, Method: Composition-based stats.
Identities = 17/71 (23%), Positives = 32/71 (45%)
Frame = +3
Query: 197 VLAVALDNSVYLWSASSGDILQLLQMEQPGEYISSVAWIKEGNYLAVGTSSAEVQLWDVQ 256
+++ + D +W +SG L L ++ +S V + G Y+ T ++LWD
Sbjct: 99 IVSSSYDGLCRIWDTASGQCLXTL-IDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYS 275
Query: 257 QQKRLRNMTSH 267
+ K L+ H
Sbjct: 276 KGKCLKTYVGH 308
>03044
Length = 1952
Score = 37.4 bits (85), Expect = 0.014, Method: Compositional matrix adjust.
Identities = 23/71 (32%), Positives = 29/71 (40%)
Frame = -2
Query: 304 TLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPGEGGWVPLQTFTQHQGAVKAVAW 363
TL H Q V G+ WAP + + G D VW +G W P + A V W
Sbjct: 1669 TLGEHGQRVTGIDWAPKSNRIVTCGADRNAYVWTYQ--DGKWQPHLVILRINRAATCVKW 1496
Query: 364 CPWQSNVLATG 374
P + N A G
Sbjct: 1495 SP-EENKFAVG 1466
Score = 28.9 bits (63), Expect = 5.0, Method: Compositional matrix adjust.
Identities = 17/73 (23%), Positives = 34/73 (46%), Gaps = 2/73 (2%)
Frame = -2
Query: 190 VDWS--SGNVLAVALDNSVYLWSASSGDILQLLQMEQPGEYISSVAWIKEGNYLAVGTSS 247
+DW+ S ++ D + Y+W+ G L + + + V W E N AVG+S+
Sbjct: 1636 IDWAPKSNRIVTCGADRNAYVWTYQDGKWQPHLVILRINRAATCVKWSPEENKFAVGSSA 1457
Query: 248 AEVQLWDVQQQKR 260
+ + +++ R
Sbjct: 1456 RLISVSYYEEEHR 1418
>15337
Length = 860
Score = 37.4 bits (85), Expect = 0.015, Method: Compositional matrix adjust.
Identities = 17/61 (27%), Positives = 29/61 (47%), Gaps = 8/61 (13%)
Frame = -1
Query: 302 VATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWP--------SAPGEGGWVPLQTFTQ 353
+ T+ + + + W+PDG+++ +GG D+LV VW G WV + F
Sbjct: 224 IGTMKSYFGGLLCVCWSPDGKYIVTGGEDDLVTVWSFHEKRVVCRGHGHKSWVNVVAFDI 45
Query: 354 H 354
H
Sbjct: 44 H 42
>12960
Length = 550
Score = 37.0 bits (84), Expect = 0.018, Method: Compositional matrix adjust.
Identities = 24/88 (27%), Positives = 40/88 (45%)
Frame = +2
Query: 299 EHHVATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPGEGGWVPLQTFTQHQGAV 358
E + T GH EV + + D + SGG D V ++ A G+ L+ + H G V
Sbjct: 269 ELFLKTYIGHGHEVLDAQGSGDNSQICSGGIDKTVVLFDVASGQA----LRKYRDHAGTV 436
Query: 359 KAVAWCPWQSNVLATGGGTSDRHIRIWN 386
V + + +L+ G+ D +R W+
Sbjct: 437 NCVKFNEESTVILS---GSLDNTVRAWD 511
>14555
Length = 627
Score = 37.0 bits (84), Expect = 0.018, Method: Compositional matrix adjust.
Identities = 16/44 (36%), Positives = 25/44 (56%)
Frame = -3
Query: 427 IWKYPTMAKVAELKGHTSRVLSLTMSPDGATVASAAADETLRLW 470
+W + L GH +RV L +SPDG ++ + + D TLR+W
Sbjct: 388 VWDALKGMRSTILYGHDNRVSCLRISPDGTSLCTGSWDYTLRIW 257
Score = 28.5 bits (62), Expect = 6.2, Method: Compositional matrix adjust.
Identities = 13/32 (40%), Positives = 17/32 (53%)
Frame = -3
Query: 305 LSGHSQEVCGLRWAPDGRHLASGGNDNLVNVW 336
L GH V LR +PDG L +G D + +W
Sbjct: 352 LYGHDNRVSCLRISPDGTSLCTGSWDYTLRIW 257
>12140
Length = 727
Score = 37.0 bits (84), Expect = 0.021, Method: Compositional matrix adjust.
Identities = 19/44 (43%), Positives = 22/44 (50%)
Frame = +2
Query: 322 RHLASGGNDNLVNVWPSAPGEGGWVPLQTFTQHQGAVKAVAWCP 365
+ SGG DNLV +W E GWV Q H V+ VAW P
Sbjct: 263 KRFVSGGCDNLVKIWR--EDETGWVEDQKLEGHSDWVRDVAWAP 388
>37142
Length = 327
Score = 36.6 bits (83), Expect = 0.023, Method: Compositional matrix adjust.
Identities = 17/37 (45%), Positives = 27/37 (72%)
Frame = +2
Query: 351 FTQHQGAVKAVAWCPWQSNVLATGGGTSDRHIRIWNV 387
T+H GAVKA+ + P+Q+N+LA+G S+ I IW++
Sbjct: 92 LTKHTGAVKALDFNPFQTNLLASGA--SESEIYIWDL 196
>10162
Length = 1629
Score = 35.8 bits (81), Expect = 0.042, Method: Compositional matrix adjust.
Identities = 42/159 (26%), Positives = 63/159 (39%), Gaps = 12/159 (7%)
Frame = +3
Query: 189 LVDWSSGNVLAVA--LDNSVYLWSASSGDILQLLQM------EQPGEYISSVAWIKEGNY 240
VD S+ N L ++ D + +++ SSG + + + SVA+ Y
Sbjct: 384 CVDCSADNALIMSGCADATAKVFNVSSGKLXSAFNCAASQDSQDKDNSVESVAFCPVSPY 563
Query: 241 LAVGTSSAEVQLWDVQQQKRLRNMTSHSARVGSLSWNS--YILXXXXXXXXXXXXDVRVA 298
A T+S VQ+WD+ R+ H V L W+S +L D R
Sbjct: 564 AATATNSGSVQVWDLPTSVA-RHSFQHPEGVCKLQWSSSTALLYTACLDGVMRVWDARSG 740
Query: 299 EHHVATLSGHSQEVCGLRW--APDGRHLASGGNDNLVNV 335
A L+GH++ C L + DG L SG D V
Sbjct: 741 ASK-AVLTGHARNSCILDFDVTRDGTCLVSGSEDGTARV 854
Score = 35.0 bits (79), Expect = 0.064, Method: Compositional matrix adjust.
Identities = 57/279 (20%), Positives = 104/279 (37%), Gaps = 6/279 (2%)
Frame = +3
Query: 197 VLAVALDNSVYLWSASSGDILQLLQMEQPGEYISSVAWIKEGNYLAVGTSSAEVQLWDVQ 256
+LA V+LW S D ++ ++ G+ + G Y+ VG S V+LWD++
Sbjct: 72 LLAGTQGGEVWLWQVPSQDYSKMKMLQSHGQPSLCGKILPNGKYVCVGYSDGVVKLWDLK 251
Query: 257 QQKRLRNMTSHSARVGSLSWNSYILXXXXXXXXXXXXDVRVAEHHVATLSGHSQEVCGLR 316
+ +W ++ + E V +C +
Sbjct: 252 TGTAVH------------TWQHSVMPEEEMPERNSSDEEDGEEVEVEREEDTVAILC-VD 392
Query: 317 WAPDGRHLASGGNDNLVNVWPSAPGE----GGWVPLQTFTQHQGAVKAVAWCPWQSNVLA 372
+ D + SG D V+ + G+ Q +V++VA+CP S A
Sbjct: 393 CSADNALIMSGCADATAKVFNVSSGKLXSAFNCAASQDSQDKDNSVESVAFCP-VSPYAA 569
Query: 373 TGGGTSDRHIRIWNVCSGACLSAVDAHSQVCSILWSPHYKELISGHGFAQNQLVIWKYPT 432
T T+ +++W++ + + VC + WS L + + +W +
Sbjct: 570 T--ATNSGSVQVWDLPTSVARHSFQHPEGVCKLQWSSSTALLYT--ACLDGVMRVWDARS 737
Query: 433 MAKVAELKGH--TSRVLSLTMSPDGATVASAAADETLRL 469
A A L GH S +L ++ DG + S + D T R+
Sbjct: 738 GASKAVLTGHARNSCILDFDVTRDGTCLVSGSEDGTARV 854
>18981
Length = 407
Score = 35.4 bits (80), Expect = 0.051, Method: Composition-based stats.
Identities = 23/97 (23%), Positives = 44/97 (45%), Gaps = 2/97 (2%)
Frame = -2
Query: 376 GTSDRHIRIWNVCSGACLSAVDAHSQ--VCSILWSPHYKELISGHGFAQNQLVIWKYPTM 433
+DR +R+W + + L + H+ C ++ + ++SG L++W+ T
Sbjct: 370 AATDRTLRVWCLKNTCLLHTLRGHNDDVECVCIYG---RRVVSGSW--DKTLIVWEVDTG 206
Query: 434 AKVAELKGHTSRVLSLTMSPDGATVASAAADETLRLW 470
V +L GHT + ++ D S +AD +R W
Sbjct: 205 RPVHQLHGHTEAITAVQF--DEGKAVSGSADGDVRTW 101
Score = 33.5 bits (75), Expect = 0.22, Method: Composition-based stats.
Identities = 27/91 (29%), Positives = 40/91 (43%), Gaps = 1/91 (1%)
Frame = -2
Query: 304 TLSGHSQEV-CGLRWAPDGRHLASGGNDNLVNVWPSAPGEGGWVPLQTFTQHQGAVKAVA 362
TL GH+ +V C + GR + SG D + VW G P+ H A+ AV
Sbjct: 313 TLRGHNDDVECVCIY---GRRVVSGSWDKTLIVWEVDTGR----PVHQLHGHTEAITAV- 158
Query: 363 WCPWQSNVLATGGGTSDRHIRIWNVCSGACL 393
Q + G++D +R W + +G CL
Sbjct: 157 ----QFDEGKAVSGSADGDVRTWALDTGQCL 77
>38177
Length = 430
Score = 35.0 bits (79), Expect = 0.064, Method: Compositional matrix adjust.
Identities = 23/91 (25%), Positives = 38/91 (41%)
Frame = +3
Query: 232 VAWIKEGNYLAVGTSSAEVQLWDVQQQKRLRNMTSHSARVGSLSWNSYILXXXXXXXXXX 291
+AW EG L G SS E LW+ + +H V ++ W+++
Sbjct: 6 LAWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDVSVRAMRWSNHDQWMVTADHSGY 185
Query: 292 XXDVRVAEHHVATLSGHSQEVCGLRWAPDGR 322
+ ++V GH + + G+R AP GR
Sbjct: 186 IKYWQSNMNNVKMFQGHKEPIRGVRLAPPGR 278
>21921
Length = 1341
Score = 35.0 bits (79), Expect = 0.071, Method: Compositional matrix adjust.
Identities = 22/82 (26%), Positives = 35/82 (42%), Gaps = 5/82 (6%)
Frame = -1
Query: 334 NVWPSAPGEGGWVPLQT-----FTQHQGAVKAVAWCPWQSNVLATGGGTSDRHIRIWNVC 388
++ P P P T + H G V+++ CP + G + D IR W V
Sbjct: 561 DLLPKLPKPKDLRPFPTTQALVYKGHTGIVRSI--CPDPTGQWLVSG-SDDGTIRFWEVS 391
Query: 389 SGACLSAVDAHSQVCSILWSPH 410
SG C+ + V S+ W+P+
Sbjct: 390 SGRCMKTLQVGGCVTSVAWNPN 325
Score = 29.3 bits (64), Expect = 3.4, Method: Compositional matrix adjust.
Identities = 17/50 (34%), Positives = 24/50 (48%), Gaps = 5/50 (10%)
Frame = -1
Query: 430 YPTMAKVAELKGHTSRVLSLTMSPDGATVASAAADETLRLW-----RCFE 474
+PT + KGHT V S+ P G + S + D T+R W RC +
Sbjct: 519 FPTTQALV-YKGHTGIVRSICPDPTGQWLVSGSDDGTIRFWEVSSGRCMK 373
>26107
Length = 1338
Score = 34.7 bits (78), Expect = 0.082, Method: Compositional matrix adjust.
Identities = 27/83 (32%), Positives = 38/83 (45%), Gaps = 3/83 (3%)
Frame = -3
Query: 306 SGHSQEVCGLRWA--PDGRHLASGGNDNLVNVWP-SAPGEGGWVPLQTFTQHQGAVKAVA 362
+GH + +R A PDG++L SG N +W P + PL H V AV
Sbjct: 439 AGHRNDTFFVRCAISPDGKYLLSGSGRNTGVIWEVDKPNKR---PL-FLIGHTEDVSAVD 272
Query: 363 WCPWQSNVLATGGGTSDRHIRIW 385
WC ++V + DR +RIW
Sbjct: 271 WC--STDVCKLATVSDDRSLRIW 209
Score = 28.5 bits (62), Expect = 6.5, Method: Compositional matrix adjust.
Identities = 16/47 (34%), Positives = 20/47 (42%), Gaps = 1/47 (2%)
Frame = -3
Query: 425 LVIWKYPTMAKVAELKGHTSRVLSLTMSPDG-ATVASAAADETLRLW 470
+ +W T KV GH V S+ P A AS A D + LW
Sbjct: 1015 VALWDVETTTKVTTFIGHKCSVRSVASCPSSPAQCASGARDGHIMLW 875
>03395
Length = 2795
Score = 34.7 bits (78), Expect = 0.092, Method: Compositional matrix adjust.
Identities = 36/157 (22%), Positives = 63/157 (40%), Gaps = 6/157 (3%)
Frame = +2
Query: 321 GRHLASGGNDNLVNVWPSA----PGEGGWVPLQTFTQHQGAVKAVAWCPWQSNVLATGGG 376
G L SGG + V VW G+ + +H+G V A+ +N
Sbjct: 32 GTKLVSGGGEGQVRVWDIVKDMLTGKTRGDLVANMKEHKGKVTAI---QIHTNDRCCVSA 202
Query: 377 TSDRHIRIWNVCSGACLSAVDAHSQV-CSILWSPHYKELISGHGFAQNQLVIWKYPTMAK 435
++D IW++ + V A++ C L SG +++ W+
Sbjct: 203 STDGSTIIWDLITNTRSQIVLANTLFKCVCFGGKDLHILTSG---TDHKIGYWEVGDGGL 373
Query: 436 VAELKG-HTSRVLSLTMSPDGATVASAAADETLRLWR 471
+ EL+G T + ++ + DG T+ + D L+LWR
Sbjct: 374 LRELEGSQTGAINTIDIDRDGQTILTGGEDSLLKLWR 484
Score = 29.6 bits (65), Expect = 3.3, Method: Compositional matrix adjust.
Identities = 28/147 (19%), Positives = 52/147 (35%), Gaps = 1/147 (0%)
Frame = +2
Query: 196 NVLAVALDNSVYLWSASSGDILQLLQMEQPGEYISSVAWIKEGNYLAVGTSSAEVQLWDV 255
++L D+ + W G +L+ L+ Q G I+++ ++G + G + ++LW
Sbjct: 311 HILTSGTDHKIGYWEVGDGGLLRELEGSQTGA-INTIDIDRDGQTILTGGEDSLLKLW-- 481
Query: 256 QQQKRLRNMTSHSARVGSLSWNSYILXXXXXXXXXXXXDVRVAEHHVA-TLSGHSQEVCG 314
R E V T GHS ++
Sbjct: 482 ----------------------------------------RYNEGEVTHTGIGHSNQITK 541
Query: 315 LRWAPDGRHLASGGNDNLVNVWPSAPG 341
R P+ ++ SGG D +++W G
Sbjct: 542 ARICPNRHYIVSGGEDGALHIWKFPDG 622
>31864
Length = 545
Score = 34.7 bits (78), Expect = 0.099, Method: Compositional matrix adjust.
Identities = 16/39 (41%), Positives = 20/39 (51%)
Frame = +2
Query: 297 VAEHHVATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNV 335
+ E A L GH + L + PDG+ ASGG D V V
Sbjct: 305 IYEEEFARLKGHFGPINSLAFHPDGKSYASGGEDGFVRV 421
Score = 31.2 bits (69), Expect = 0.95, Method: Compositional matrix adjust.
Identities = 27/107 (25%), Positives = 42/107 (39%), Gaps = 14/107 (13%)
Frame = +2
Query: 377 TSDRHIRIWNVCSGACLSAVDAHSQVCSILWSPHYKELISGHGFAQNQLVIWKYPTMA-- 434
+ D ++++ S CL V S SP ++ G G Q+ + + T A
Sbjct: 107 SKDTTAKLFDSESLMCLKTYKTERPVNSAAISPILDHVVLGGG--QDAMEVTTTSTKAGK 280
Query: 435 ------------KVAELKGHTSRVLSLTMSPDGATVASAAADETLRL 469
+ A LKGH + SL PDG + AS D +R+
Sbjct: 281 FDSRFFHLIYEEEFARLKGHFGPINSLAFHPDGKSYASGGEDGFVRV 421
>27270
Length = 1078
Score = 34.3 bits (77), Expect = 0.12, Method: Compositional matrix adjust.
Identities = 41/166 (24%), Positives = 67/166 (40%), Gaps = 23/166 (13%)
Frame = +2
Query: 330 DNLVNVWPSAPGEGGWVPLQTFTQ----HQGAVKAVAWCPWQSNVLATGGGTSDRHIRIW 385
D+ V SA G G ++T T ++G KAV W+++ + D H+ W
Sbjct: 176 DSAVVAVGSADGSVGLYSVETHTYTHMLNKGHSKAVTDMCWRADGRTLYSSSLDGHVIGW 355
Query: 386 NVCSGACLSAVDA-----HSQVCSILWSPHYKELISGHGFAQNQLVIWKYPTMAKVAELK 440
NV + + A H C L S L++ A + + +W T + E
Sbjct: 356 NVNTLHMIEKWKATSGRHHGVHCVCLCSS--SRLLT----ADHTIKMWDLTTKNVLQEFS 517
Query: 441 GHTSRVLSL--TMSPDGA------------TVASAAADETLRLWRC 472
GH++ V+ L + P ++AAAD T+ +WRC
Sbjct: 518 GHSTEVIKLLPVLKPSSEQNDIGDSNLACYVFSAAAADRTINVWRC 655
>07665
Length = 435
Score = 33.9 bits (76), Expect = 0.15, Method: Compositional matrix adjust.
Identities = 24/96 (25%), Positives = 44/96 (45%), Gaps = 9/96 (9%)
Frame = -2
Query: 385 WNVCSGACLSAVDAHSQVCSILWSPHYKELISGHGFAQNQLVIWKYPTMAKVAEL----- 439
W++ G L ++ + + ++ +SP+ L +G + + IW V EL
Sbjct: 392 WDLNDGKNLYTLEHNDIINALCFSPNRYWLCVAYGPS---IKIWDLACKKTVEELRPEVV 222
Query: 440 ----KGHTSRVLSLTMSPDGATVASAAADETLRLWR 471
K + LSL S DG T+ + +D T+R+W+
Sbjct: 221 SPTSKAEQPQCLSLAWSTDGQTLFAGYSDNTIRVWQ 114
>02090
Length = 1841
Score = 33.9 bits (76), Expect = 0.16, Method: Compositional matrix adjust.
Identities = 13/50 (26%), Positives = 23/50 (46%)
Frame = -3
Query: 421 AQNQLVIWKYPTMAKVAELKGHTSRVLSLTMSPDGATVASAAADETLRLW 470
+ + +W V + +GHT + +SPDG + + D T+R W
Sbjct: 1566 SDGNIAVWDLHNQTLVRQFQGHTDGASCIDISPDGTKLWTGGLDNTVRSW 1417
Score = 33.1 bits (74), Expect = 0.27, Method: Compositional matrix adjust.
Identities = 41/157 (26%), Positives = 61/157 (38%)
Frame = -3
Query: 315 LRWAPDGRHLASGGNDNLVNVWPSAPGEGGWVPLQTFTQHQGAVKAVAWCPWQSNVLATG 374
L +PDG+ S +D + VW ++ F H + P L TG
Sbjct: 1608 LAISPDGKVCFSCCSDGNIAVWDLHNQ----TLVRQFQGHTDGASCIDISP-DGTKLWTG 1444
Query: 375 GGTSDRHIRIWNVCSGACLSAVDAHSQVCSILWSPHYKELISGHGFAQNQLVIWKYPTMA 434
G D +R W++ G L D SQ+ S+ + P + L G + +++ P
Sbjct: 1443 G--LDNTVRSWDLREGRQLQQHDFSSQIFSLGYCPTGEWLAVGMESSNVEVLHHSKPDKY 1270
Query: 435 KVAELKGHTSRVLSLTMSPDGATVASAAADETLRLWR 471
+L H S VLSL + G S D L WR
Sbjct: 1269 ---QLHLHESCVLSLKFAYCGKWFVSTGKDNLLNAWR 1168
Score = 32.0 bits (71), Expect = 0.57, Method: Compositional matrix adjust.
Identities = 33/148 (22%), Positives = 59/148 (39%), Gaps = 3/148 (2%)
Frame = -3
Query: 197 VLAVALDNSVYLWSASSGDILQLLQMEQPGEYISSVAWIKEGNYLAVGTSSAEVQLWDVQ 256
+ D ++ +W + +++ Q G S + +G L G V+ WD++
Sbjct: 1581 CFSCCSDGNIAVWDLHNQTLVRQFQGHTDGA--SCIDISPDGTKLWTGGLDNTVRSWDLR 1408
Query: 257 QQKRLRNMTSHSARVGSLSWNSYILXXXXXXXXXXXXDVRVAEH---HVATLSGHSQEVC 313
+ ++L+ S+++ SL Y +V V H L H V
Sbjct: 1407 EGRQLQQH-DFSSQIFSLG---YCPTGEWLAVGMESSNVEVLHHSKPDKYQLHLHESCVL 1240
Query: 314 GLRWAPDGRHLASGGNDNLVNVWPSAPG 341
L++A G+ S G DNL+N W + G
Sbjct: 1239 SLKFAYCGKWFVSTGKDNLLNAWRTPYG 1156
>30176
Length = 365
Score = 33.1 bits (74), Expect = 0.27, Method: Composition-based stats.
Identities = 14/33 (42%), Positives = 22/33 (66%)
Frame = +2
Query: 439 LKGHTSRVLSLTMSPDGATVASAAADETLRLWR 471
LK HTS V +LT G +AS + D+T+++W+
Sbjct: 8 LKSHTSTVWNLTFDKTGTRLASCSDDKTIKIWQ 106
>07542
Length = 1027
Score = 32.7 bits (73), Expect = 0.37, Method: Compositional matrix adjust.
Identities = 18/62 (29%), Positives = 34/62 (54%), Gaps = 1/62 (1%)
Frame = +1
Query: 201 ALDNSVYLWSASSGDILQLLQMEQPGEYISSVAWIKEGNYL-AVGTSSAEVQLWDVQQQK 259
A + V ++ G + + + QPG I+ VA+ K+GNYL A G E+ +D++ +
Sbjct: 1 AFNGDVAIYDVPHGGLTAVFE-GQPGG-ITHVAFSKDGNYLFAGGRKDPEINCFDIRNPE 174
Query: 260 RL 261
++
Sbjct: 175 KI 180
>15972
Length = 1069
Score = 32.0 bits (71), Expect = 0.57, Method: Compositional matrix adjust.
Identities = 18/63 (28%), Positives = 30/63 (47%)
Frame = +3
Query: 347 PLQTFTQHQGAVKAVAWCPWQSNVLATGGGTSDRHIRIWNVCSGACLSAVDAHSQVCSIL 406
P +TF+ H+G V+ +A P L + DR +R+WN +G + S+
Sbjct: 213 PERTFSGHKGPVRHLAVHPSGKLTLTV---SQDRTLRLWNNMNGRIAFISNMKEAAESVR 383
Query: 407 WSP 409
W+P
Sbjct: 384 WAP 392
>31054
Length = 392
Score = 32.0 bits (71), Expect = 0.60, Method: Compositional matrix adjust.
Identities = 15/43 (34%), Positives = 24/43 (55%)
Frame = -2
Query: 428 WKYPTMAKVAELKGHTSRVLSLTMSPDGATVASAAADETLRLW 470
WK+P + L GH + + +L ++ DG V S A + T+ LW
Sbjct: 334 WKFPDGNFIQNLSGHNAIINTLAVNSDGVLV-SGADNGTMHLW 209
>19863
Length = 502
Score = 31.6 bits (70), Expect = 0.86, Method: Compositional matrix adjust.
Identities = 18/64 (28%), Positives = 30/64 (46%)
Frame = +1
Query: 413 ELISGHGFAQNQLVIWKYPTMAKVAELKGHTSRVLSLTMSPDGATVASAAADETLRLWRC 472
+L+SG + +V+W + L+GH V + S D + S + D T+R+W
Sbjct: 13 QLVSGS--SDMSIVVWDVENGVQKLRLQGHAGWVNDVHFSQDQCWLLSCSNDNTVRIWNI 186
Query: 473 FELD 476
E D
Sbjct: 187 EESD 198
>35607
Length = 475
Score = 30.4 bits (67), Expect = 1.5, Method: Compositional matrix adjust.
Identities = 30/101 (29%), Positives = 42/101 (41%)
Frame = +2
Query: 371 LATGGGTSDRHIRIWNVCSGACLSAVDAHSQVCSILWSPHYKELISGHGFAQNQLVIWKY 430
L TGG D +R W++ G L D SQ+ S+ + P L G + +++
Sbjct: 23 LWTGG--LDNTVRSWDLREGRQLQQHDFSSQIFSLGYCPTGDWLAVGMESSNVEVLHHSK 196
Query: 431 PTMAKVAELKGHTSRVLSLTMSPDGATVASAAADETLRLWR 471
P +L H S VLSL + G S D L WR
Sbjct: 197 PDKY---QLHLHESCVLSLKFAYCGKWFVSTGKDNLLNAWR 310
Score = 30.4 bits (67), Expect = 1.6, Method: Compositional matrix adjust.
Identities = 28/108 (25%), Positives = 45/108 (41%), Gaps = 3/108 (2%)
Frame = +2
Query: 237 EGNYLAVGTSSAEVQLWDVQQQKRLRNMTSHSARVGSLSWNSYILXXXXXXXXXXXXDVR 296
+G L G V+ WD+++ ++L+ S+++ SL Y +V
Sbjct: 11 DGTKLWTGGLDNTVRSWDLREGRQLQQH-DFSSQIFSLG---YCPTGDWLAVGMESSNVE 178
Query: 297 VAEH---HVATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPG 341
V H L H V L++A G+ S G DNL+N W + G
Sbjct: 179 VLHHSKPDKYQLHLHESCVLSLKFAYCGKWFVSTGKDNLLNAWRTPYG 322
>22113
Length = 614
Score = 30.4 bits (67), Expect = 1.5, Method: Compositional matrix adjust.
Identities = 14/34 (41%), Positives = 18/34 (52%)
Frame = +3
Query: 308 HSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPG 341
H V LR+A G+ S G DNL+N W + G
Sbjct: 99 HESCVLSLRFATCGKWFVSTGKDNLLNAWRTPYG 200
>34511
Length = 1037
Score = 30.0 bits (66), Expect = 2.1, Method: Compositional matrix adjust.
Identities = 13/32 (40%), Positives = 21/32 (65%)
Frame = +3
Query: 439 LKGHTSRVLSLTMSPDGATVASAAADETLRLW 470
L GH +RV L ++ +G +VA+ + D LR+W
Sbjct: 60 LAGHDNRVSCLGVTENGMSVATGSWDSFLRVW 155
>20172
Length = 479
Score = 30.0 bits (66), Expect = 2.2, Method: Composition-based stats.
Identities = 18/48 (37%), Positives = 25/48 (52%), Gaps = 2/48 (4%)
Frame = +2
Query: 169 PSLPDRILDAPEIRNDYYLNLVDWSSG--NVLAVALDNSVYLWSASSG 214
P DR D P R + + DW+ G +V+ ALD + LWS +SG
Sbjct: 233 PKYSDRYGDEP--RRNRMGEITDWNDGKKSVVGEALDKAKDLWSRASG 370
>12841
Length = 1364
Score = 30.0 bits (66), Expect = 2.4, Method: Compositional matrix adjust.
Identities = 22/75 (29%), Positives = 31/75 (41%), Gaps = 1/75 (1%)
Frame = +1
Query: 299 EHHVATLSGHSQEVCGLRWAPDGRHLA-SGGNDNLVNVWPSAPGEGGWVPLQTFTQHQGA 357
E ++ T SGH+ V +RW+P + S D + +W P+ TF
Sbjct: 1018 EQYLETYSGHTAPVYHIRWSPFVSDIFLSCSADWSIRLWHQDRT----TPILTFHSSTKT 1185
Query: 358 VKAVAWCPWQSNVLA 372
V V W P S V A
Sbjct: 1186 VHDVCWSPRSSTVFA 1230
>15118
Length = 1074
Score = 29.6 bits (65), Expect = 2.7, Method: Compositional matrix adjust.
Identities = 48/200 (24%), Positives = 73/200 (36%), Gaps = 16/200 (8%)
Frame = +3
Query: 190 VDWSS-GNVLAVALDNSVYLWSASSGDILQLLQMEQPGEY---------ISSVAWIKEGN 239
VD SS GN +AV +S+ DI L + G + + VA+
Sbjct: 75 VDISSCGNYVAVG-------YSSGHLDIYNLQSGKHRGSFGDTVAHVSGVRGVAFDAFNC 233
Query: 240 YLAVGTSSAEVQLWDVQQQKRLR------NMTSHSARVGSLSWNSYILXXXXXXXXXXXX 293
L +++ W + R R M+ +R+ L +S +L
Sbjct: 234 LLITAGGDCDIKFWRFGSRDRARVLLKELKMSEGISRI-LLHRDSNMLAVVLEDFTVSVI 410
Query: 294 DVRVAEHHVATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPGEGGWVPLQTFTQ 353
DV V SGHS + L ++ DGR L + D V W G + F
Sbjct: 411 DVDTLRV-VRVFSGHSNSITDLSFSGDGRWLITASMDCTVRTWSLVHGR----LIDCFAV 575
Query: 354 HQGAVKAVAWCPWQSNVLAT 373
+ AV ++ P Q + LAT
Sbjct: 576 -EAAVTSLTMSPSQ-DFLAT 629
Score = 28.9 bits (63), Expect = 5.0, Method: Compositional matrix adjust.
Identities = 13/44 (29%), Positives = 23/44 (52%)
Frame = +3
Query: 427 IWKYPTMAKVAELKGHTSRVLSLTMSPDGATVASAAADETLRLW 470
+ T+ V GH++ + L+ S DG + +A+ D T+R W
Sbjct: 405 VIDVDTLRVVRVFSGHSNSITDLSFSGDGRWLITASMDCTVRTW 536
>12409
Length = 674
Score = 29.6 bits (65), Expect = 2.8, Method: Compositional matrix adjust.
Identities = 12/33 (36%), Positives = 19/33 (57%)
Frame = -1
Query: 308 HSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAP 340
H VC R++ G+H+AS D +V +W +P
Sbjct: 338 HQSAVCYSRFSLSGQHIASLDADGIVKIWTWSP 240
>01707
Length = 757
Score = 29.3 bits (64), Expect = 3.5, Method: Compositional matrix adjust.
Identities = 15/47 (31%), Positives = 25/47 (53%)
Frame = +3
Query: 295 VRVAEHHVATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPG 341
V++++ T G+ QE+CG+R P + + GN N + S PG
Sbjct: 114 VQMSQQRDLTACGY-QEICGIRR*PSHQEDCNAGNSNAEAIKTSQPG 251
>36111
Length = 687
Score = 29.3 bits (64), Expect = 4.0, Method: Compositional matrix adjust.
Identities = 14/48 (29%), Positives = 24/48 (50%)
Frame = +2
Query: 229 ISSVAWIKEGNYLAVGTSSAEVQLWDVQQQKRLRNMTSHSARVGSLSW 276
+++VA+ N A G S V +WD +KRL + + SL++
Sbjct: 239 VNAVAFHNVYNTFATGGSDGYVNIWDGFHKKRLCXFHRYPTSIASLAF 382
>01462
Length = 995
Score = 28.9 bits (63), Expect = 4.5, Method: Compositional matrix adjust.
Identities = 12/52 (23%), Positives = 23/52 (44%)
Frame = +2
Query: 419 GFAQNQLVIWKYPTMAKVAELKGHTSRVLSLTMSPDGATVASAAADETLRLW 470
G ++ +W + ++GH + + M D SA+ D T+R+W
Sbjct: 251 GAGDRKIHVWDIEAGQYLNAMEGHKDYIHKVVMKNDAQECVSASEDGTVRMW 406
>21105
Length = 650
Score = 28.9 bits (63), Expect = 5.6, Method: Compositional matrix adjust.
Identities = 14/68 (20%), Positives = 34/68 (50%)
Frame = +1
Query: 203 DNSVYLWSASSGDILQLLQMEQPGEYISSVAWIKEGNYLAVGTSSAEVQLWDVQQQKRLR 262
D + + ++G ++ M + ++S+A G YL G+ ++LW++ + ++
Sbjct: 127 DRHIRFFDNNTGKLIH--AMVAHLDSVTSLAVDPNGLYLLSGSHDCSIRLWNLDSKTCVQ 300
Query: 263 NMTSHSAR 270
+TSH +
Sbjct: 301 EITSHRKK 324
>31384
Length = 474
Score = 28.5 bits (62), Expect = 7.0, Method: Compositional matrix adjust.
Identities = 12/29 (41%), Positives = 18/29 (62%)
Frame = -1
Query: 442 HTSRVLSLTMSPDGATVASAAADETLRLW 470
HT VL + S DG V +A+ D+T ++W
Sbjct: 138 HTGPVLDVDWSDDGTKVFTASCDKTAKVW 52
>27475
Length = 369
Score = 28.1 bits (61), Expect = 9.6, Method: Compositional matrix adjust.
Identities = 23/82 (28%), Positives = 42/82 (51%), Gaps = 2/82 (2%)
Frame = +2
Query: 351 FTQHQGAVKAVAWCPWQSNVLATGGGTSDRHIRIWNVCS-GACLSAVDAH-SQVCSILWS 408
FT H G V V W P + ++ + G+ D +++W+ S A L ++ H ++ ++ WS
Sbjct: 56 FTSHTGWVTGVDWSPTREHLFLS--GSYDNVLKLWDTRSPKATLYDMNWHEDRILAVDWS 229
Query: 409 PHYKELISGHGFAQNQLVIWKY 430
EL+ G N+L ++ Y
Sbjct: 230 --IPELLLSGG-VDNKLHVFSY 286
>30295
Length = 593
Score = 28.1 bits (61), Expect = 9.7, Method: Compositional matrix adjust.
Identities = 12/33 (36%), Positives = 17/33 (51%)
Frame = +2
Query: 304 TLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVW 336
TL H ++ + WA D R+L S D + VW
Sbjct: 230 TLRXHLAKIYAMHWATDSRNLVSASQDGKLIVW 328
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000156825 | hsapiens_gene_ensembl |
Methyl-CpG-binding domain protein 3 (Methyl-CpG-binding protein MBD3).
[Source:Uniprot/SWISSPROT;Acc:O95983]
(291 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
31546 251 3e-67
18721 30 1.6
04994 28 4.0
34009 28 4.1
>31546
Length = 1180
Score = 251 bits (641), Expect = 3e-67, Method: Compositional matrix adjust.
Identities = 126/243 (51%), Positives = 178/243 (73%), Gaps = 5/243 (2%)
Frame = -2
Query: 10 ALPQGWEREEVPRRSGLSAGHRDVFYYSPSGKKFRSKPQLARYLGGSMDLSTFDFRTGKM 69
ALP GW+REEV R+SGLSAG DV+YYSP G+K RSKPQLAR LG + DLS FDFR+G++
Sbjct: 966 ALPPGWKREEVVRQSGLSAGKTDVYYYSPDGRKIRSKPQLARLLGDNFDLSVFDFRSGRV 787
Query: 70 LMSKMNKSRQR--VRYDSSNQVKGKPDLNTALPVRQTASIFKQPVTKITNHPSNKVKSDP 127
+ S + KS+++ +D + V + D + LP+RQTASIFKQPVT I NH +K K+D
Sbjct: 786 IYSAVRKSKRQKGSPFDFARGV--RVDSSLVLPIRQTASIFKQPVTVIRNHLDSKTKTDL 613
Query: 128 QKAV-DQPRQLFWEKKLSGLNAFDIAEELVKTMDLPKGLQGVGPGCTDETLLSAIASALH 186
+ V +QPRQLFWEK+L GL A D EE ++ MDLP+ + GVGP + E++L +I++ALH
Sbjct: 612 KHGVQEQPRQLFWEKRLQGLRACDNTEESIQCMDLPRNMNGVGPELSTESVLQSISAALH 433
Query: 187 TSTMPITGQLS--AAVEKNPGVWLNTTQPLCKAFMVTDEDIRKQEELVQQVRKRLEEALM 244
+T+P+TGQ S + ++KNPGV ++ QP + +V++EDI++QE+ V + RKRL++AL
Sbjct: 432 LNTVPVTGQSSSRSQIQKNPGVNIDANQPHIQHMLVSEEDIQRQEQRVVEARKRLQDALR 253
Query: 245 ADM 247
+M
Sbjct: 252 EEM 244
>18721
Length = 457
Score = 29.6 bits (65), Expect = 1.6, Method: Compositional matrix adjust.
Identities = 25/80 (31%), Positives = 38/80 (47%), Gaps = 4/80 (5%)
Frame = +2
Query: 95 LNTALPVRQTASIFKQPVTKITNHPSNKVKSDPQKAVDQPRQLFWEKKLSGLNAF----D 150
+N +L +R +F+Q V + + S++V + QK VD L W + L F D
Sbjct: 185 VNLSLTLRLDGRVFRQ*VHRPRDGASSRVVTFKQKXVDLITDLLWSQTFVVL-VFGRQQD 361
Query: 151 IAEELVKTMDLPKGLQGVGP 170
+ E V+T GL VGP
Sbjct: 362 VQE--VQTATFTSGL--VGP 409
>04994
Length = 969
Score = 28.1 bits (61), Expect = 4.0, Method: Compositional matrix adjust.
Identities = 21/71 (29%), Positives = 35/71 (49%), Gaps = 2/71 (2%)
Frame = +2
Query: 150 DIAEELVKTMDLPKGLQGVGPGCTDETLLSAIASALHTSTMPITGQLSAAVEKNPGVWLN 209
+I E+V M GL GP + ++ +++ H+ST+P LS +NPG W+
Sbjct: 533 NIGLEVVGLMW--TGLMWTGP----QGVIPYVST--HSSTIPHCLALSMLAHQNPGPWVQ 688
Query: 210 TTQP--LCKAF 218
+ P +C F
Sbjct: 689 GSSPKLVCVVF 721
>34009
Length = 729
Score = 28.1 bits (61), Expect = 4.1, Method: Compositional matrix adjust.
Identities = 17/66 (25%), Positives = 30/66 (45%)
Frame = -3
Query: 113 TKITNHPSNKVKSDPQKAVDQPRQLFWEKKLSGLNAFDIAEELVKTMDLPKGLQGVGPGC 172
T I N NK+KSDP ++ P ++KK + N ++ ++L + C
Sbjct: 589 TNIYNKNKNKIKSDPNVKIEHPYVTKYKKK-TIFNLTNVKNHHFMELNLNXKKKSKSNPC 413
Query: 173 TDETLL 178
++T L
Sbjct: 412 ENQTSL 395
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000265447 | hsapiens_gene_ensembl | Annexin A11
(Annexin-11) (Annexin XI) (Calcyclin-associated annexin 50) (CAP-50)
(56 kDa autoantigen). [Source:Uniprot/SWISSPROT;Acc:P50995]
(505 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
32521 252 3e-67
06659 164 5e-41
36934 133 2e-31
22178 114 7e-26
17882 60 1e-18
12136 87 1e-17
29756 65 8e-11
13827 64 1e-10
07233 28 6.1
>32521
Length = 1241
Score = 252 bits (643), Expect = 3e-67, Method: Compositional matrix adjust.
Identities = 125/270 (46%), Positives = 179/270 (66%)
Frame = +2
Query: 233 KQRQQILLSFKTAYGKDLIKDLKSELSGNFEKTILALMKTPVLFDIYEIKEAIKGVGTDE 292
+QR++I L++KT +GKDL K+L ELSGNF+ + ++ P FD +I +A+KG+GTDE
Sbjct: 2 EQRREINLTYKTMFGKDLGKELSGELSGNFKTLCVEMLLGPAEFDAKQINKAVKGLGTDE 181
Query: 293 ACLIEILASRSNEHIRELNRAYKAEFKKTLEEAIRSDTSGHFQRLLISLSQGNRDESTNV 352
LIEI+ +R+N + + AYK ++K +E I DTSG F+RLLI Q NR E
Sbjct: 182 RALIEIICTRTNAQLTAMKEAYKTMYQKDVETDIEGDTSGPFKRLLIGCLQANRPEGQEF 361
Query: 353 DMSLAQRDAQELYAAGENRLGTDESKFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKSICR 412
D + A++DAQ L AGE + GTDES+FN V+ SRS L A F EY ++ +DIE SI
Sbjct: 362 DRNKAKQDAQALLEAGEKKWGTDESRFNVVIVSRSFPQLRATFQEYAKLANKDIEDSISS 541
Query: 413 EMSGDLEEGMLAVVKCLKNTPAFFAERLNKAMRGAGTKDRTLIRIMVSRSETDLLDIRSE 472
EMSGD + GML VV+ +++ FA L++AM+G GT D TL+R++ SR E D++ I+ E
Sbjct: 542 EMSGDXKNGMLTVVRVIRSKATHFATELHRAMKGLGTDDDTLVRVVASRCEVDMVQIKEE 721
Query: 473 YKRMYGKSLYHDISGDTSGDYRKILLKICG 502
++R + ++LY I DTSGDYR +L + G
Sbjct: 722 FQRNFKQTLYSFIVDDTSGDYRLMLCNLIG 811
Score = 82.8 bits (203), Expect = 3e-16, Method: Compositional matrix adjust.
Identities = 63/225 (28%), Positives = 117/225 (52%), Gaps = 12/225 (5%)
Frame = +2
Query: 205 DAEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILLSFKTAYGKDLIKDLKSELSGNFEK 264
DA+ + KA+KG GTDE+A+I+ + +R+N Q + ++KT Y KD+ D++ + SG F++
Sbjct: 134 DAKQINKAVKGLGTDERALIEIICTRTNAQLTAMKEAYKTMYQKDVETDIEGDTSGPFKR 313
Query: 265 TILALMKTP----VLFDIYEIKEAIKGV--------GTDEACLIEILASRSNEHIRELNR 312
++ ++ FD + K+ + + GTDE+ ++ SRS +R +
Sbjct: 314 LLIGCLQANRPEGQEFDRNKAKQDAQALLEAGEKKWGTDESRFNVVIVSRSFPQLRATFQ 493
Query: 313 AYKAEFKKTLEEAIRSDTSGHFQRLLISLSQGNRDESTNVDMSLAQRDAQELYAAGENRL 372
Y K +E++I S+ SG + ++++ + R ++T+ A EL+ A + L
Sbjct: 494 EYAKLANKDIEDSISSEMSGDXKNGMLTVVRVIRSKATHF--------ATELHRAMKG-L 646
Query: 373 GTDESKFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGD 417
GTD+ V+ SR +V + E+QR + + I + SGD
Sbjct: 647 GTDDDTLVRVVASRCEVDMVQIKEEFQRNFKQTLYSFIVDDTSGD 781
Score = 34.3 bits (77), Expect = 0.13, Method: Compositional matrix adjust.
Identities = 19/68 (27%), Positives = 33/68 (48%)
Frame = +2
Query: 206 AEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILLSFKTAYGKDLIKDLKSELSGNFEKT 265
A L +AMKG GTD+ ++ + SR QI F+ + + L + + SG++
Sbjct: 614 ATELHRAMKGLGTDDDTLVRVVASRCEVDMVQIKEEFQRNFKQTLYSFIVDDTSGDYRLM 793
Query: 266 ILALMKTP 273
+ L+ P
Sbjct: 794 LCNLIGQP 817
>06659
Length = 776
Score = 164 bits (416), Expect = 5e-41, Method: Compositional matrix adjust.
Identities = 98/223 (43%), Positives = 139/223 (62%), Gaps = 3/223 (1%)
Frame = -3
Query: 281 IKEAIKGVGTDEACLIEILASRSNEHIRELNRAYKAEFKKTLEEAIRSDTSGHFQRLLIS 340
+ +AI G GTDE CLI+I+ +R N+ ++E+ YK EF+ LEE +++DT G+F+RL+IS
Sbjct: 774 LHDAISGAGTDEKCLIDIMCTRDNDEMKEIKEKYKEEFESELEEDLQADTGGYFRRLMIS 595
Query: 341 LSQGNRD--ESTNVDMSLAQRDAQELYAAGENRLGTDESKFNAVLCSRSRAHLVAVFNEY 398
L G RD + A DAQ+ AGEN GT+E+ NA+LC S A L +Y
Sbjct: 594 LCVGGRDYDNWWXANEDKAVEDAQKFLEAGENAWGTEEADMNAILCRTSPAQLCKTIEKY 415
Query: 399 QRMT-GRDIEKSICREMSGDLEEGMLAVVKCLKNTPAFFAERLNKAMRGAGTKDRTLIRI 457
+ +T G+ +E+SI E S DL +G LA+V+ ++ P +FA RLN G GT D LIRI
Sbjct: 414 EELTEGKTMEESIRSECSDDLXDGYLAIVESARSMPRYFARRLNDCFSGLGTSDNDLIRI 235
Query: 458 MVSRSETDLLDIRSEYKRMYGKSLYHDISGDTSGDYRKILLKI 500
+VSRSE DL I+ Y+ MY K L + + GDY+++LL I
Sbjct: 234 IVSRSEVDLEAIKQAYEEMYEKPLTEAVESECGGDYKRLLLAI 106
Score = 50.8 bits (120), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 57/233 (24%), Positives = 109/233 (46%), Gaps = 15/233 (6%)
Frame = -3
Query: 209 LRKAMKGFGTDEQAIIDCLGSRSNKQRQQILLSFKTAYGKDLIKDLKSELSGNFEKTILA 268
L A+ G GTDE+ +ID + +R N + ++I +K + +L +DL+++ G F + +++
Sbjct: 774 LHDAISGAGTDEKCLIDIMCTRDNDEMKEIKEKYKEEFESELEEDLQADTGGYFRRLMIS 595
Query: 269 LMKTPVLFDIYEIKEAIKGV--------------GTDEACLIEILASRSNEHIRELNRAY 314
L +D + K V GT+EA + IL S + + Y
Sbjct: 594 LCVGGRDYDNWWXANEDKAVEDAQKFLEAGENAWGTEEADMNAILCRTSPAQLCKTIEKY 415
Query: 315 KAEFK-KTLEEAIRSDTSGHFQRLLISLSQGNRDESTNVDMSLAQRDAQELYAAGENRLG 373
+ + KT+EE+IRS+ S +++ + R S+ + A+ L LG
Sbjct: 414 EELTEGKTMEESIRSECSDDLXDGYLAIVESAR--------SMPRYFARRLNDCFSG-LG 262
Query: 374 TDESKFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDLEEGMLAVV 426
T ++ ++ SRS L A+ Y+ M + + +++ E GD + +LA++
Sbjct: 261 TSDNDLIRIIVSRSEVDLEAIKQAYEEMYEKPLTEAVESECGGDYKRLLLAIL 103
Score = 37.0 bits (84), Expect = 0.019, Method: Compositional matrix adjust.
Identities = 24/67 (35%), Positives = 42/67 (62%), Gaps = 1/67 (1%)
Frame = -3
Query: 440 LNKAMRGAGTKDRTLIRIMVSRSETDLLDIRSEYKRMYGKSLYHDISGDTSGDYRKILLK 499
L+ A+ GAGT ++ LI IM +R ++ +I+ +YK + L D+ DT G +R++++
Sbjct: 774 LHDAISGAGTDEKCLIDIMCTRDNDEMKEIKEKYKEEFESELEEDLQADTGGYFRRLMIS 595
Query: 500 IC-GGND 505
+C GG D
Sbjct: 594 LCVGGRD 574
>36934
Length = 667
Score = 133 bits (335), Expect = 2e-31, Method: Compositional matrix adjust.
Identities = 77/218 (35%), Positives = 129/218 (59%), Gaps = 1/218 (0%)
Frame = +3
Query: 205 DAEVLRKAMKGFG-TDEQAIIDCLGSRSNKQRQQILLSFKTAYGKDLIKDLKSELSGNFE 263
DAE L KAM G G T E +++ + RSN QRQ + +K Y +DL + L+SEL+G+FE
Sbjct: 27 DAERLHKAMSGMGVTHEDTVLEIIIKRSNSQRQTLKKKYKEMYKRDLAEHLQSELTGDFE 206
Query: 264 KTILALMKTPVLFDIYEIKEAIKGVGTDEACLIEILASRSNEHIRELNRAYKAEFKKTLE 323
+ IL L+ PV +D + + +A+ G+GT+E LI IL + + + + + YK + + L+
Sbjct: 207 ELILGLLMPPVEYDAFCLNKAVDGLGTNEDVLIGILCTANPKELSSVKEVYKKTYGEDLD 386
Query: 324 EAIRSDTSGHFQRLLISLSQGNRDESTNVDMSLAQRDAQELYAAGENRLGTDESKFNAVL 383
AI+ DTSG F+ LL++LS+G RD+S +V+ A++DAQ+L + + G F +
Sbjct: 387 SAIKGDTSGGFEDLLLALSRGERDQSKSVNEKEAKQDAQKLCPDKK*KTGHG**NFQYID 566
Query: 384 CSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDLEEG 421
++ + A F EY+++ R C ++S + +G
Sbjct: 567 DKENKQQMKATFVEYEKLRVR-----ACWKLSKNHHQG 665
Score = 70.9 bits (172), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 46/147 (31%), Positives = 75/147 (51%)
Frame = +3
Query: 357 AQRDAQELYAAGENRLGTDESKFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSG 416
A DA+ L+ A T E ++ RS + + +Y+ M RD+ + + E++G
Sbjct: 18 AAEDAERLHKAMSGMGVTHEDTVLEIIIKRSNSQRQTLKKKYKEMYKRDLAEHLQSELTG 197
Query: 417 DLEEGMLAVVKCLKNTPAFFAERLNKAMRGAGTKDRTLIRIMVSRSETDLLDIRSEYKRM 476
D EE +L ++ AF LNKA+ G GT + LI I+ + + +L ++ YK+
Sbjct: 198 DFEELILGLLMPPVEYDAFC---LNKAVDGLGTNEDVLIGILCTANPKELSSVKEVYKKT 368
Query: 477 YGKSLYHDISGDTSGDYRKILLKICGG 503
YG+ L I GDTSG + +LL + G
Sbjct: 369 YGEDLDSAIKGDTSGGFEDLLLALSRG 449
>22178
Length = 655
Score = 114 bits (286), Expect = 7e-26, Method: Compositional matrix adjust.
Identities = 72/157 (45%), Positives = 98/157 (62%), Gaps = 6/157 (3%)
Frame = +1
Query: 352 VDMSLAQRDAQELYAAG---ENRLGTDESKFNAVL--CSRSRAHLVAV-FNEYQRMTGRD 405
VD ++A ++A ELY AG + R G + + ++V + H V N Q GR
Sbjct: 1 VDPTIAMQEAHELYKAG*KGKRRDGRGDVQPHSVPEELRATAGHF*RVQANLRQGHRGRH 180
Query: 406 IEKSICREMSGDLEEGMLAVVKCLKNTPAFFAERLNKAMRGAGTKDRTLIRIMVSRSETD 465
E ++ G L LA+V+ +NTPA+FAERL K+M+GAGT D+ LIR +VSRSE D
Sbjct: 181 QE*DEW-QLGGGL---FLAIVRVARNTPAYFAERLYKSMKGAGTNDKALIRAIVSRSEND 348
Query: 466 LLDIRSEYKRMYGKSLYHDISGDTSGDYRKILLKICG 502
L I+ E++RMYGK+L I GDTSGDY+KILL +CG
Sbjct: 349 LGFIKQEFQRMYGKTLASYIKGDTSGDYKKILLALCG 459
Score = 45.1 bits (105), Expect(2) = 3e-08, Method: Compositional matrix adjust.
Identities = 24/82 (29%), Positives = 45/82 (54%)
Frame = +1
Query: 260 GNFEKTILALMKTPVLFDIYEIKEAIKGVGTDEACLIEILASRSNEHIRELNRAYKAEFK 319
G F + TP F + +++KG GT++ LI + SRS + + + ++ +
Sbjct: 211 GLFLAIVRVARNTPAYFA-ERLYKSMKGAGTNDKALIRAIVSRSENDLGFIKQEFQRMYG 387
Query: 320 KTLEEAIRSDTSGHFQRLLISL 341
KTL I+ DTSG ++++L++L
Sbjct: 388 KTLASYIKGDTSGDYKKILLAL 453
Score = 30.8 bits (68), Expect(2) = 3e-08, Method: Compositional matrix adjust.
Identities = 17/50 (34%), Positives = 27/50 (54%)
Frame = +2
Query: 214 KGFGTDEQAIIDCLGSRSNKQRQQILLSFKTAYGKDLIKDLKSELSGNFE 263
+ GTDE+ L R+ Q + +++ GKD+ +KSE+SGN E
Sbjct: 59 ESVGTDEETFNRILCLRNYGQLRATFDAYRQISGKDIEDAIKSEMSGNLE 208
Score = 48.5 bits (114), Expect = 5e-06, Method: Compositional matrix adjust.
Identities = 28/68 (41%), Positives = 41/68 (60%)
Frame = +1
Query: 202 PLRDAEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILLSFKTAYGKDLIKDLKSELSGN 261
P AE L K+MKG GT+++A+I + SRS I F+ YGK L +K + SG+
Sbjct: 250 PAYFAERLYKSMKGAGTNDKALIRAIVSRSENDLGFIKQEFQRMYGKTLASYIKGDTSGD 429
Query: 262 FEKTILAL 269
++K +LAL
Sbjct: 430 YKKILLAL 453
Score = 31.6 bits (70), Expect = 0.70, Method: Compositional matrix adjust.
Identities = 18/50 (36%), Positives = 28/50 (56%)
Frame = +2
Query: 286 KGVGTDEACLIEILASRSNEHIRELNRAYKAEFKKTLEEAIRSDTSGHFQ 335
+ VGTDE IL R+ +R AY+ K +E+AI+S+ SG+ +
Sbjct: 59 ESVGTDEETFNRILCLRNYGQLRATFDAYRQISGKDIEDAIKSEMSGNLE 208
>17882
Length = 489
Score = 60.1 bits (144), Expect(2) = 1e-18, Method: Compositional matrix adjust.
Identities = 32/64 (50%), Positives = 43/64 (67%)
Frame = -1
Query: 439 RLNKAMRGAGTKDRTLIRIMVSRSETDLLDIRSEYKRMYGKSLYHDISGDTSGDYRKILL 498
RL++ + GT D LIRI+VSRSE DL DI+ Y Y K+L ++ DTSGDY+++LL
Sbjct: 369 RLHQVL---GTNDSRLIRIIVSRSEIDLQDIKDVYLSKYKKTLESAVASDTSGDYKRLLL 199
Query: 499 KICG 502
I G
Sbjct: 198 AIVG 187
Score = 51.2 bits (121), Expect(2) = 1e-18, Method: Compositional matrix adjust.
Identities = 20/44 (45%), Positives = 32/44 (72%)
Frame = -2
Query: 402 TGRDIEKSICREMSGDLEEGMLAVVKCLKNTPAFFAERLNKAMR 445
G+D+ SI EMSGD E G+ A+V+C+KN P +FA++L+ ++
Sbjct: 488 AGKDLLSSISSEMSGDFETGLRAIVRCMKNRPEYFADKLHDCIK 357
Score = 52.8 bits (125), Expect(2) = 7e-10, Method: Compositional matrix adjust.
Identities = 23/54 (42%), Positives = 41/54 (75%)
Frame = -1
Query: 288 VGTDEACLIEILASRSNEHIRELNRAYKAEFKKTLEEAIRSDTSGHFQRLLISL 341
+GT+++ LI I+ SRS ++++ Y +++KKTLE A+ SDTSG ++RLL+++
Sbjct: 354 LGTNDSRLIRIIVSRSEIDLQDIKDVYLSKYKKTLESAVASDTSGDYKRLLLAI 193
Score = 28.5 bits (62), Expect(2) = 7e-10, Method: Compositional matrix adjust.
Identities = 11/25 (44%), Positives = 19/25 (76%)
Frame = -2
Query: 247 GKDLIKDLKSELSGNFEKTILALMK 271
GKDL+ + SE+SG+FE + A+++
Sbjct: 485 GKDLLSSISSEMSGDFETGLRAIVR 411
Score = 32.7 bits (73), Expect = 0.39, Method: Compositional matrix adjust.
Identities = 16/55 (29%), Positives = 31/55 (56%)
Frame = -1
Query: 372 LGTDESKFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDLEEGMLAVV 426
LGT++S+ ++ SRS L + + Y + +E ++ + SGD + +LA+V
Sbjct: 354 LGTNDSRLIRIIVSRSEIDLQDIKDVYLSKYKKTLESAVASDTSGDYKRLLLAIV 190
>12136
Length = 445
Score = 87.4 bits (215), Expect = 1e-17, Method: Compositional matrix adjust.
Identities = 47/106 (44%), Positives = 66/106 (62%), Gaps = 7/106 (6%)
Frame = +3
Query: 250 LIKDLKSELSGNFEKTILALMKTPVLFDIYEIKEAIKGVGTDEACLIEILASRSNEHIRE 309
LI+++K ELSG++++ ++AL P +D + IKEAI G GTDE L+EIL +R+N I+E
Sbjct: 3 LIEEIKGELSGDYKELVMALFVAPAEYDAWCIKEAIYGPGTDEMALMEILMTRTNAQIKE 182
Query: 310 LNRAYKAEFK-------KTLEEAIRSDTSGHFQRLLISLSQGNRDE 348
L Y + +E+ I D SG F+RLLIS SQG R E
Sbjct: 183 LRSIYPSVLNDHYHGRTPKIEQDIEDDCSGDFKRLLISASQGGRFE 320
>29756
Length = 496
Score = 64.7 bits (156), Expect = 8e-11, Method: Compositional matrix adjust.
Identities = 35/74 (47%), Positives = 46/74 (62%), Gaps = 1/74 (1%)
Frame = +3
Query: 198 PGFDPLRDAEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILLSFKTAYGKDLIKDL-KS 256
P F+ D + LRKAMKGFGTDE+AIID LG R++ QRQ + L +K + K +
Sbjct: 258 PRFNAEEDVQKLRKAMKGFGTDEKAIIDILGYRTSDQRQNLKLMYKNLFWKRFGAGF*RV 437
Query: 257 ELSGNFEKTILALM 270
+G FE +LALM
Sbjct: 438 N*AGAFEDAMLALM 479
>13827
Length = 483
Score = 64.3 bits (155), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 28/59 (47%), Positives = 42/59 (71%)
Frame = -1
Query: 445 RGAGTKDRTLIRIMVSRSETDLLDIRSEYKRMYGKSLYHDISGDTSGDYRKILLKICGG 503
RG GT DRTLIR++V+R E D+ I+ E++ YG++L + D SGDYR+++L + GG
Sbjct: 444 RGMGTDDRTLIRVVVTRCEVDMKQIKQEFQNRYGQALEAFVRDDISGDYRRLMLALVGG 268
Score = 45.4 bits (106), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 17/59 (28%), Positives = 38/59 (64%)
Frame = -1
Query: 286 KGVGTDEACLIEILASRSNEHIRELNRAYKAEFKKTLEEAIRSDTSGHFQRLLISLSQG 344
+G+GTD+ LI ++ +R ++++ + ++ + + LE +R D SG ++RL+++L G
Sbjct: 444 RGMGTDDRTLIRVVVTRCEVDMKQIKQEFQNRYGQALEAFVRDDISGDYRRLMLALVGG 268
Score = 37.7 bits (86), Expect = 0.011, Method: Compositional matrix adjust.
Identities = 17/57 (29%), Positives = 35/57 (61%)
Frame = -1
Query: 214 KGFGTDEQAIIDCLGSRSNKQRQQILLSFKTAYGKDLIKDLKSELSGNFEKTILALM 270
+G GTD++ +I + +R +QI F+ YG+ L ++ ++SG++ + +LAL+
Sbjct: 444 RGMGTDDRTLIRVVVTRCEVDMKQIKQEFQNRYGQALEAFVRDDISGDYRRLMLALV 274
Score = 30.8 bits (68), Expect = 1.3, Method: Compositional matrix adjust.
Identities = 16/55 (29%), Positives = 29/55 (52%)
Frame = -1
Query: 372 LGTDESKFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDLEEGMLAVV 426
+GTD+ V+ +R + + E+Q G+ +E + ++SGD MLA+V
Sbjct: 438 MGTDDRTLIRVVVTRCEVDMKQIKQEFQNRYGQALEAFVRDDISGDYRRLMLALV 274
>07233
Length = 1497
Score = 28.5 bits (62), Expect = 6.1, Method: Compositional matrix adjust.
Identities = 11/39 (28%), Positives = 22/39 (56%)
Frame = -3
Query: 378 KFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSG 416
+F AVL + + +V +F EY + T + C++++G
Sbjct: 1027 EFPAVLVNVQQKQIVGMFREYXKPTVNPVLTEFCKQLTG 911
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000347886 | hsapiens_gene_ensembl |
Methyl-CpG-binding domain protein 3 (Methyl-CpG-binding protein MBD3).
[Source:Uniprot/SWISSPROT;Acc:O95983]
(291 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
31546 251 3e-67
18721 30 1.6
04994 28 4.0
34009 28 4.1
>31546
Length = 1180
Score = 251 bits (641), Expect = 3e-67, Method: Compositional matrix adjust.
Identities = 126/243 (51%), Positives = 178/243 (73%), Gaps = 5/243 (2%)
Frame = -2
Query: 10 ALPQGWEREEVPRRSGLSAGHRDVFYYSPSGKKFRSKPQLARYLGGSMDLSTFDFRTGKM 69
ALP GW+REEV R+SGLSAG DV+YYSP G+K RSKPQLAR LG + DLS FDFR+G++
Sbjct: 966 ALPPGWKREEVVRQSGLSAGKTDVYYYSPDGRKIRSKPQLARLLGDNFDLSVFDFRSGRV 787
Query: 70 LMSKMNKSRQR--VRYDSSNQVKGKPDLNTALPVRQTASIFKQPVTKITNHPSNKVKSDP 127
+ S + KS+++ +D + V + D + LP+RQTASIFKQPVT I NH +K K+D
Sbjct: 786 IYSAVRKSKRQKGSPFDFARGV--RVDSSLVLPIRQTASIFKQPVTVIRNHLDSKTKTDL 613
Query: 128 QKAV-DQPRQLFWEKKLSGLNAFDIAEELVKTMDLPKGLQGVGPGCTDETLLSAIASALH 186
+ V +QPRQLFWEK+L GL A D EE ++ MDLP+ + GVGP + E++L +I++ALH
Sbjct: 612 KHGVQEQPRQLFWEKRLQGLRACDNTEESIQCMDLPRNMNGVGPELSTESVLQSISAALH 433
Query: 187 TSTMPITGQLS--AAVEKNPGVWLNTTQPLCKAFMVTDEDIRKQEELVQQVRKRLEEALM 244
+T+P+TGQ S + ++KNPGV ++ QP + +V++EDI++QE+ V + RKRL++AL
Sbjct: 432 LNTVPVTGQSSSRSQIQKNPGVNIDANQPHIQHMLVSEEDIQRQEQRVVEARKRLQDALR 253
Query: 245 ADM 247
+M
Sbjct: 252 EEM 244
>18721
Length = 457
Score = 29.6 bits (65), Expect = 1.6, Method: Compositional matrix adjust.
Identities = 25/80 (31%), Positives = 38/80 (47%), Gaps = 4/80 (5%)
Frame = +2
Query: 95 LNTALPVRQTASIFKQPVTKITNHPSNKVKSDPQKAVDQPRQLFWEKKLSGLNAF----D 150
+N +L +R +F+Q V + + S++V + QK VD L W + L F D
Sbjct: 185 VNLSLTLRLDGRVFRQ*VHRPRDGASSRVVTFKQKXVDLITDLLWSQTFVVL-VFGRQQD 361
Query: 151 IAEELVKTMDLPKGLQGVGP 170
+ E V+T GL VGP
Sbjct: 362 VQE--VQTATFTSGL--VGP 409
>04994
Length = 969
Score = 28.1 bits (61), Expect = 4.0, Method: Compositional matrix adjust.
Identities = 21/71 (29%), Positives = 35/71 (49%), Gaps = 2/71 (2%)
Frame = +2
Query: 150 DIAEELVKTMDLPKGLQGVGPGCTDETLLSAIASALHTSTMPITGQLSAAVEKNPGVWLN 209
+I E+V M GL GP + ++ +++ H+ST+P LS +NPG W+
Sbjct: 533 NIGLEVVGLMW--TGLMWTGP----QGVIPYVST--HSSTIPHCLALSMLAHQNPGPWVQ 688
Query: 210 TTQP--LCKAF 218
+ P +C F
Sbjct: 689 GSSPKLVCVVF 721
>34009
Length = 729
Score = 28.1 bits (61), Expect = 4.1, Method: Compositional matrix adjust.
Identities = 17/66 (25%), Positives = 30/66 (45%)
Frame = -3
Query: 113 TKITNHPSNKVKSDPQKAVDQPRQLFWEKKLSGLNAFDIAEELVKTMDLPKGLQGVGPGC 172
T I N NK+KSDP ++ P ++KK + N ++ ++L + C
Sbjct: 589 TNIYNKNKNKIKSDPNVKIEHPYVTKYKKK-TIFNLTNVKNHHFMELNLNXKKKSKSNPC 413
Query: 173 TDETLL 178
++T L
Sbjct: 412 ENQTSL 395
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000353827 | hsapiens_gene_ensembl | Annexin A11
(Annexin-11) (Annexin XI) (Calcyclin-associated annexin 50) (CAP-50)
(56 kDa autoantigen). [Source:Uniprot/SWISSPROT;Acc:P50995]
(505 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
32521 252 3e-67
06659 164 5e-41
36934 133 2e-31
22178 114 7e-26
17882 60 1e-18
12136 87 1e-17
29756 65 8e-11
13827 64 1e-10
07233 28 6.1
>32521
Length = 1241
Score = 252 bits (643), Expect = 3e-67, Method: Compositional matrix adjust.
Identities = 125/270 (46%), Positives = 179/270 (66%)
Frame = +2
Query: 233 KQRQQILLSFKTAYGKDLIKDLKSELSGNFEKTILALMKTPVLFDIYEIKEAIKGVGTDE 292
+QR++I L++KT +GKDL K+L ELSGNF+ + ++ P FD +I +A+KG+GTDE
Sbjct: 2 EQRREINLTYKTMFGKDLGKELSGELSGNFKTLCVEMLLGPAEFDAKQINKAVKGLGTDE 181
Query: 293 ACLIEILASRSNEHIRELNRAYKAEFKKTLEEAIRSDTSGHFQRLLISLSQGNRDESTNV 352
LIEI+ +R+N + + AYK ++K +E I DTSG F+RLLI Q NR E
Sbjct: 182 RALIEIICTRTNAQLTAMKEAYKTMYQKDVETDIEGDTSGPFKRLLIGCLQANRPEGQEF 361
Query: 353 DMSLAQRDAQELYAAGENRLGTDESKFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKSICR 412
D + A++DAQ L AGE + GTDES+FN V+ SRS L A F EY ++ +DIE SI
Sbjct: 362 DRNKAKQDAQALLEAGEKKWGTDESRFNVVIVSRSFPQLRATFQEYAKLANKDIEDSISS 541
Query: 413 EMSGDLEEGMLAVVKCLKNTPAFFAERLNKAMRGAGTKDRTLIRIMVSRSETDLLDIRSE 472
EMSGD + GML VV+ +++ FA L++AM+G GT D TL+R++ SR E D++ I+ E
Sbjct: 542 EMSGDXKNGMLTVVRVIRSKATHFATELHRAMKGLGTDDDTLVRVVASRCEVDMVQIKEE 721
Query: 473 YKRMYGKSLYHDISGDTSGDYRKILLKICG 502
++R + ++LY I DTSGDYR +L + G
Sbjct: 722 FQRNFKQTLYSFIVDDTSGDYRLMLCNLIG 811
Score = 82.8 bits (203), Expect = 3e-16, Method: Compositional matrix adjust.
Identities = 63/225 (28%), Positives = 117/225 (52%), Gaps = 12/225 (5%)
Frame = +2
Query: 205 DAEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILLSFKTAYGKDLIKDLKSELSGNFEK 264
DA+ + KA+KG GTDE+A+I+ + +R+N Q + ++KT Y KD+ D++ + SG F++
Sbjct: 134 DAKQINKAVKGLGTDERALIEIICTRTNAQLTAMKEAYKTMYQKDVETDIEGDTSGPFKR 313
Query: 265 TILALMKTP----VLFDIYEIKEAIKGV--------GTDEACLIEILASRSNEHIRELNR 312
++ ++ FD + K+ + + GTDE+ ++ SRS +R +
Sbjct: 314 LLIGCLQANRPEGQEFDRNKAKQDAQALLEAGEKKWGTDESRFNVVIVSRSFPQLRATFQ 493
Query: 313 AYKAEFKKTLEEAIRSDTSGHFQRLLISLSQGNRDESTNVDMSLAQRDAQELYAAGENRL 372
Y K +E++I S+ SG + ++++ + R ++T+ A EL+ A + L
Sbjct: 494 EYAKLANKDIEDSISSEMSGDXKNGMLTVVRVIRSKATHF--------ATELHRAMKG-L 646
Query: 373 GTDESKFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGD 417
GTD+ V+ SR +V + E+QR + + I + SGD
Sbjct: 647 GTDDDTLVRVVASRCEVDMVQIKEEFQRNFKQTLYSFIVDDTSGD 781
Score = 34.3 bits (77), Expect = 0.13, Method: Compositional matrix adjust.
Identities = 19/68 (27%), Positives = 33/68 (48%)
Frame = +2
Query: 206 AEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILLSFKTAYGKDLIKDLKSELSGNFEKT 265
A L +AMKG GTD+ ++ + SR QI F+ + + L + + SG++
Sbjct: 614 ATELHRAMKGLGTDDDTLVRVVASRCEVDMVQIKEEFQRNFKQTLYSFIVDDTSGDYRLM 793
Query: 266 ILALMKTP 273
+ L+ P
Sbjct: 794 LCNLIGQP 817
>06659
Length = 776
Score = 164 bits (416), Expect = 5e-41, Method: Compositional matrix adjust.
Identities = 98/223 (43%), Positives = 139/223 (62%), Gaps = 3/223 (1%)
Frame = -3
Query: 281 IKEAIKGVGTDEACLIEILASRSNEHIRELNRAYKAEFKKTLEEAIRSDTSGHFQRLLIS 340
+ +AI G GTDE CLI+I+ +R N+ ++E+ YK EF+ LEE +++DT G+F+RL+IS
Sbjct: 774 LHDAISGAGTDEKCLIDIMCTRDNDEMKEIKEKYKEEFESELEEDLQADTGGYFRRLMIS 595
Query: 341 LSQGNRD--ESTNVDMSLAQRDAQELYAAGENRLGTDESKFNAVLCSRSRAHLVAVFNEY 398
L G RD + A DAQ+ AGEN GT+E+ NA+LC S A L +Y
Sbjct: 594 LCVGGRDYDNWWXANEDKAVEDAQKFLEAGENAWGTEEADMNAILCRTSPAQLCKTIEKY 415
Query: 399 QRMT-GRDIEKSICREMSGDLEEGMLAVVKCLKNTPAFFAERLNKAMRGAGTKDRTLIRI 457
+ +T G+ +E+SI E S DL +G LA+V+ ++ P +FA RLN G GT D LIRI
Sbjct: 414 EELTEGKTMEESIRSECSDDLXDGYLAIVESARSMPRYFARRLNDCFSGLGTSDNDLIRI 235
Query: 458 MVSRSETDLLDIRSEYKRMYGKSLYHDISGDTSGDYRKILLKI 500
+VSRSE DL I+ Y+ MY K L + + GDY+++LL I
Sbjct: 234 IVSRSEVDLEAIKQAYEEMYEKPLTEAVESECGGDYKRLLLAI 106
Score = 50.8 bits (120), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 57/233 (24%), Positives = 109/233 (46%), Gaps = 15/233 (6%)
Frame = -3
Query: 209 LRKAMKGFGTDEQAIIDCLGSRSNKQRQQILLSFKTAYGKDLIKDLKSELSGNFEKTILA 268
L A+ G GTDE+ +ID + +R N + ++I +K + +L +DL+++ G F + +++
Sbjct: 774 LHDAISGAGTDEKCLIDIMCTRDNDEMKEIKEKYKEEFESELEEDLQADTGGYFRRLMIS 595
Query: 269 LMKTPVLFDIYEIKEAIKGV--------------GTDEACLIEILASRSNEHIRELNRAY 314
L +D + K V GT+EA + IL S + + Y
Sbjct: 594 LCVGGRDYDNWWXANEDKAVEDAQKFLEAGENAWGTEEADMNAILCRTSPAQLCKTIEKY 415
Query: 315 KAEFK-KTLEEAIRSDTSGHFQRLLISLSQGNRDESTNVDMSLAQRDAQELYAAGENRLG 373
+ + KT+EE+IRS+ S +++ + R S+ + A+ L LG
Sbjct: 414 EELTEGKTMEESIRSECSDDLXDGYLAIVESAR--------SMPRYFARRLNDCFSG-LG 262
Query: 374 TDESKFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDLEEGMLAVV 426
T ++ ++ SRS L A+ Y+ M + + +++ E GD + +LA++
Sbjct: 261 TSDNDLIRIIVSRSEVDLEAIKQAYEEMYEKPLTEAVESECGGDYKRLLLAIL 103
Score = 37.0 bits (84), Expect = 0.019, Method: Compositional matrix adjust.
Identities = 24/67 (35%), Positives = 42/67 (62%), Gaps = 1/67 (1%)
Frame = -3
Query: 440 LNKAMRGAGTKDRTLIRIMVSRSETDLLDIRSEYKRMYGKSLYHDISGDTSGDYRKILLK 499
L+ A+ GAGT ++ LI IM +R ++ +I+ +YK + L D+ DT G +R++++
Sbjct: 774 LHDAISGAGTDEKCLIDIMCTRDNDEMKEIKEKYKEEFESELEEDLQADTGGYFRRLMIS 595
Query: 500 IC-GGND 505
+C GG D
Sbjct: 594 LCVGGRD 574
>36934
Length = 667
Score = 133 bits (335), Expect = 2e-31, Method: Compositional matrix adjust.
Identities = 77/218 (35%), Positives = 129/218 (59%), Gaps = 1/218 (0%)
Frame = +3
Query: 205 DAEVLRKAMKGFG-TDEQAIIDCLGSRSNKQRQQILLSFKTAYGKDLIKDLKSELSGNFE 263
DAE L KAM G G T E +++ + RSN QRQ + +K Y +DL + L+SEL+G+FE
Sbjct: 27 DAERLHKAMSGMGVTHEDTVLEIIIKRSNSQRQTLKKKYKEMYKRDLAEHLQSELTGDFE 206
Query: 264 KTILALMKTPVLFDIYEIKEAIKGVGTDEACLIEILASRSNEHIRELNRAYKAEFKKTLE 323
+ IL L+ PV +D + + +A+ G+GT+E LI IL + + + + + YK + + L+
Sbjct: 207 ELILGLLMPPVEYDAFCLNKAVDGLGTNEDVLIGILCTANPKELSSVKEVYKKTYGEDLD 386
Query: 324 EAIRSDTSGHFQRLLISLSQGNRDESTNVDMSLAQRDAQELYAAGENRLGTDESKFNAVL 383
AI+ DTSG F+ LL++LS+G RD+S +V+ A++DAQ+L + + G F +
Sbjct: 387 SAIKGDTSGGFEDLLLALSRGERDQSKSVNEKEAKQDAQKLCPDKK*KTGHG**NFQYID 566
Query: 384 CSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDLEEG 421
++ + A F EY+++ R C ++S + +G
Sbjct: 567 DKENKQQMKATFVEYEKLRVR-----ACWKLSKNHHQG 665
Score = 70.9 bits (172), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 46/147 (31%), Positives = 75/147 (51%)
Frame = +3
Query: 357 AQRDAQELYAAGENRLGTDESKFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSG 416
A DA+ L+ A T E ++ RS + + +Y+ M RD+ + + E++G
Sbjct: 18 AAEDAERLHKAMSGMGVTHEDTVLEIIIKRSNSQRQTLKKKYKEMYKRDLAEHLQSELTG 197
Query: 417 DLEEGMLAVVKCLKNTPAFFAERLNKAMRGAGTKDRTLIRIMVSRSETDLLDIRSEYKRM 476
D EE +L ++ AF LNKA+ G GT + LI I+ + + +L ++ YK+
Sbjct: 198 DFEELILGLLMPPVEYDAFC---LNKAVDGLGTNEDVLIGILCTANPKELSSVKEVYKKT 368
Query: 477 YGKSLYHDISGDTSGDYRKILLKICGG 503
YG+ L I GDTSG + +LL + G
Sbjct: 369 YGEDLDSAIKGDTSGGFEDLLLALSRG 449
>22178
Length = 655
Score = 114 bits (286), Expect = 7e-26, Method: Compositional matrix adjust.
Identities = 72/157 (45%), Positives = 98/157 (62%), Gaps = 6/157 (3%)
Frame = +1
Query: 352 VDMSLAQRDAQELYAAG---ENRLGTDESKFNAVL--CSRSRAHLVAV-FNEYQRMTGRD 405
VD ++A ++A ELY AG + R G + + ++V + H V N Q GR
Sbjct: 1 VDPTIAMQEAHELYKAG*KGKRRDGRGDVQPHSVPEELRATAGHF*RVQANLRQGHRGRH 180
Query: 406 IEKSICREMSGDLEEGMLAVVKCLKNTPAFFAERLNKAMRGAGTKDRTLIRIMVSRSETD 465
E ++ G L LA+V+ +NTPA+FAERL K+M+GAGT D+ LIR +VSRSE D
Sbjct: 181 QE*DEW-QLGGGL---FLAIVRVARNTPAYFAERLYKSMKGAGTNDKALIRAIVSRSEND 348
Query: 466 LLDIRSEYKRMYGKSLYHDISGDTSGDYRKILLKICG 502
L I+ E++RMYGK+L I GDTSGDY+KILL +CG
Sbjct: 349 LGFIKQEFQRMYGKTLASYIKGDTSGDYKKILLALCG 459
Score = 45.1 bits (105), Expect(2) = 3e-08, Method: Compositional matrix adjust.
Identities = 24/82 (29%), Positives = 45/82 (54%)
Frame = +1
Query: 260 GNFEKTILALMKTPVLFDIYEIKEAIKGVGTDEACLIEILASRSNEHIRELNRAYKAEFK 319
G F + TP F + +++KG GT++ LI + SRS + + + ++ +
Sbjct: 211 GLFLAIVRVARNTPAYFA-ERLYKSMKGAGTNDKALIRAIVSRSENDLGFIKQEFQRMYG 387
Query: 320 KTLEEAIRSDTSGHFQRLLISL 341
KTL I+ DTSG ++++L++L
Sbjct: 388 KTLASYIKGDTSGDYKKILLAL 453
Score = 30.8 bits (68), Expect(2) = 3e-08, Method: Compositional matrix adjust.
Identities = 17/50 (34%), Positives = 27/50 (54%)
Frame = +2
Query: 214 KGFGTDEQAIIDCLGSRSNKQRQQILLSFKTAYGKDLIKDLKSELSGNFE 263
+ GTDE+ L R+ Q + +++ GKD+ +KSE+SGN E
Sbjct: 59 ESVGTDEETFNRILCLRNYGQLRATFDAYRQISGKDIEDAIKSEMSGNLE 208
Score = 48.5 bits (114), Expect = 5e-06, Method: Compositional matrix adjust.
Identities = 28/68 (41%), Positives = 41/68 (60%)
Frame = +1
Query: 202 PLRDAEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILLSFKTAYGKDLIKDLKSELSGN 261
P AE L K+MKG GT+++A+I + SRS I F+ YGK L +K + SG+
Sbjct: 250 PAYFAERLYKSMKGAGTNDKALIRAIVSRSENDLGFIKQEFQRMYGKTLASYIKGDTSGD 429
Query: 262 FEKTILAL 269
++K +LAL
Sbjct: 430 YKKILLAL 453
Score = 31.6 bits (70), Expect = 0.70, Method: Compositional matrix adjust.
Identities = 18/50 (36%), Positives = 28/50 (56%)
Frame = +2
Query: 286 KGVGTDEACLIEILASRSNEHIRELNRAYKAEFKKTLEEAIRSDTSGHFQ 335
+ VGTDE IL R+ +R AY+ K +E+AI+S+ SG+ +
Sbjct: 59 ESVGTDEETFNRILCLRNYGQLRATFDAYRQISGKDIEDAIKSEMSGNLE 208
>17882
Length = 489
Score = 60.1 bits (144), Expect(2) = 1e-18, Method: Compositional matrix adjust.
Identities = 32/64 (50%), Positives = 43/64 (67%)
Frame = -1
Query: 439 RLNKAMRGAGTKDRTLIRIMVSRSETDLLDIRSEYKRMYGKSLYHDISGDTSGDYRKILL 498
RL++ + GT D LIRI+VSRSE DL DI+ Y Y K+L ++ DTSGDY+++LL
Sbjct: 369 RLHQVL---GTNDSRLIRIIVSRSEIDLQDIKDVYLSKYKKTLESAVASDTSGDYKRLLL 199
Query: 499 KICG 502
I G
Sbjct: 198 AIVG 187
Score = 51.2 bits (121), Expect(2) = 1e-18, Method: Compositional matrix adjust.
Identities = 20/44 (45%), Positives = 32/44 (72%)
Frame = -2
Query: 402 TGRDIEKSICREMSGDLEEGMLAVVKCLKNTPAFFAERLNKAMR 445
G+D+ SI EMSGD E G+ A+V+C+KN P +FA++L+ ++
Sbjct: 488 AGKDLLSSISSEMSGDFETGLRAIVRCMKNRPEYFADKLHDCIK 357
Score = 52.8 bits (125), Expect(2) = 7e-10, Method: Compositional matrix adjust.
Identities = 23/54 (42%), Positives = 41/54 (75%)
Frame = -1
Query: 288 VGTDEACLIEILASRSNEHIRELNRAYKAEFKKTLEEAIRSDTSGHFQRLLISL 341
+GT+++ LI I+ SRS ++++ Y +++KKTLE A+ SDTSG ++RLL+++
Sbjct: 354 LGTNDSRLIRIIVSRSEIDLQDIKDVYLSKYKKTLESAVASDTSGDYKRLLLAI 193
Score = 28.5 bits (62), Expect(2) = 7e-10, Method: Compositional matrix adjust.
Identities = 11/25 (44%), Positives = 19/25 (76%)
Frame = -2
Query: 247 GKDLIKDLKSELSGNFEKTILALMK 271
GKDL+ + SE+SG+FE + A+++
Sbjct: 485 GKDLLSSISSEMSGDFETGLRAIVR 411
Score = 32.7 bits (73), Expect = 0.39, Method: Compositional matrix adjust.
Identities = 16/55 (29%), Positives = 31/55 (56%)
Frame = -1
Query: 372 LGTDESKFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDLEEGMLAVV 426
LGT++S+ ++ SRS L + + Y + +E ++ + SGD + +LA+V
Sbjct: 354 LGTNDSRLIRIIVSRSEIDLQDIKDVYLSKYKKTLESAVASDTSGDYKRLLLAIV 190
>12136
Length = 445
Score = 87.4 bits (215), Expect = 1e-17, Method: Compositional matrix adjust.
Identities = 47/106 (44%), Positives = 66/106 (62%), Gaps = 7/106 (6%)
Frame = +3
Query: 250 LIKDLKSELSGNFEKTILALMKTPVLFDIYEIKEAIKGVGTDEACLIEILASRSNEHIRE 309
LI+++K ELSG++++ ++AL P +D + IKEAI G GTDE L+EIL +R+N I+E
Sbjct: 3 LIEEIKGELSGDYKELVMALFVAPAEYDAWCIKEAIYGPGTDEMALMEILMTRTNAQIKE 182
Query: 310 LNRAYKAEFK-------KTLEEAIRSDTSGHFQRLLISLSQGNRDE 348
L Y + +E+ I D SG F+RLLIS SQG R E
Sbjct: 183 LRSIYPSVLNDHYHGRTPKIEQDIEDDCSGDFKRLLISASQGGRFE 320
>29756
Length = 496
Score = 64.7 bits (156), Expect = 8e-11, Method: Compositional matrix adjust.
Identities = 35/74 (47%), Positives = 46/74 (62%), Gaps = 1/74 (1%)
Frame = +3
Query: 198 PGFDPLRDAEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILLSFKTAYGKDLIKDL-KS 256
P F+ D + LRKAMKGFGTDE+AIID LG R++ QRQ + L +K + K +
Sbjct: 258 PRFNAEEDVQKLRKAMKGFGTDEKAIIDILGYRTSDQRQNLKLMYKNLFWKRFGAGF*RV 437
Query: 257 ELSGNFEKTILALM 270
+G FE +LALM
Sbjct: 438 N*AGAFEDAMLALM 479
>13827
Length = 483
Score = 64.3 bits (155), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 28/59 (47%), Positives = 42/59 (71%)
Frame = -1
Query: 445 RGAGTKDRTLIRIMVSRSETDLLDIRSEYKRMYGKSLYHDISGDTSGDYRKILLKICGG 503
RG GT DRTLIR++V+R E D+ I+ E++ YG++L + D SGDYR+++L + GG
Sbjct: 444 RGMGTDDRTLIRVVVTRCEVDMKQIKQEFQNRYGQALEAFVRDDISGDYRRLMLALVGG 268
Score = 45.4 bits (106), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 17/59 (28%), Positives = 38/59 (64%)
Frame = -1
Query: 286 KGVGTDEACLIEILASRSNEHIRELNRAYKAEFKKTLEEAIRSDTSGHFQRLLISLSQG 344
+G+GTD+ LI ++ +R ++++ + ++ + + LE +R D SG ++RL+++L G
Sbjct: 444 RGMGTDDRTLIRVVVTRCEVDMKQIKQEFQNRYGQALEAFVRDDISGDYRRLMLALVGG 268
Score = 37.7 bits (86), Expect = 0.011, Method: Compositional matrix adjust.
Identities = 17/57 (29%), Positives = 35/57 (61%)
Frame = -1
Query: 214 KGFGTDEQAIIDCLGSRSNKQRQQILLSFKTAYGKDLIKDLKSELSGNFEKTILALM 270
+G GTD++ +I + +R +QI F+ YG+ L ++ ++SG++ + +LAL+
Sbjct: 444 RGMGTDDRTLIRVVVTRCEVDMKQIKQEFQNRYGQALEAFVRDDISGDYRRLMLALV 274
Score = 30.8 bits (68), Expect = 1.3, Method: Compositional matrix adjust.
Identities = 16/55 (29%), Positives = 29/55 (52%)
Frame = -1
Query: 372 LGTDESKFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDLEEGMLAVV 426
+GTD+ V+ +R + + E+Q G+ +E + ++SGD MLA+V
Sbjct: 438 MGTDDRTLIRVVVTRCEVDMKQIKQEFQNRYGQALEAFVRDDISGDYRRLMLALV 274
>07233
Length = 1497
Score = 28.5 bits (62), Expect = 6.1, Method: Compositional matrix adjust.
Identities = 11/39 (28%), Positives = 22/39 (56%)
Frame = -3
Query: 378 KFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSG 416
+F AVL + + +V +F EY + T + C++++G
Sbjct: 1027 EFPAVLVNVQQKQIVGMFREYXKPTVNPVLTEFCKQLTG 911
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000361305 | hsapiens_gene_ensembl | Annexin A11
(Annexin-11) (Annexin XI) (Calcyclin-associated annexin 50) (CAP-50)
(56 kDa autoantigen). [Source:Uniprot/SWISSPROT;Acc:P50995]
(505 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
32521 252 3e-67
06659 164 5e-41
36934 133 2e-31
22178 114 7e-26
17882 60 1e-18
12136 87 1e-17
29756 65 8e-11
13827 64 1e-10
07233 28 6.1
>32521
Length = 1241
Score = 252 bits (643), Expect = 3e-67, Method: Compositional matrix adjust.
Identities = 125/270 (46%), Positives = 179/270 (66%)
Frame = +2
Query: 233 KQRQQILLSFKTAYGKDLIKDLKSELSGNFEKTILALMKTPVLFDIYEIKEAIKGVGTDE 292
+QR++I L++KT +GKDL K+L ELSGNF+ + ++ P FD +I +A+KG+GTDE
Sbjct: 2 EQRREINLTYKTMFGKDLGKELSGELSGNFKTLCVEMLLGPAEFDAKQINKAVKGLGTDE 181
Query: 293 ACLIEILASRSNEHIRELNRAYKAEFKKTLEEAIRSDTSGHFQRLLISLSQGNRDESTNV 352
LIEI+ +R+N + + AYK ++K +E I DTSG F+RLLI Q NR E
Sbjct: 182 RALIEIICTRTNAQLTAMKEAYKTMYQKDVETDIEGDTSGPFKRLLIGCLQANRPEGQEF 361
Query: 353 DMSLAQRDAQELYAAGENRLGTDESKFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKSICR 412
D + A++DAQ L AGE + GTDES+FN V+ SRS L A F EY ++ +DIE SI
Sbjct: 362 DRNKAKQDAQALLEAGEKKWGTDESRFNVVIVSRSFPQLRATFQEYAKLANKDIEDSISS 541
Query: 413 EMSGDLEEGMLAVVKCLKNTPAFFAERLNKAMRGAGTKDRTLIRIMVSRSETDLLDIRSE 472
EMSGD + GML VV+ +++ FA L++AM+G GT D TL+R++ SR E D++ I+ E
Sbjct: 542 EMSGDXKNGMLTVVRVIRSKATHFATELHRAMKGLGTDDDTLVRVVASRCEVDMVQIKEE 721
Query: 473 YKRMYGKSLYHDISGDTSGDYRKILLKICG 502
++R + ++LY I DTSGDYR +L + G
Sbjct: 722 FQRNFKQTLYSFIVDDTSGDYRLMLCNLIG 811
Score = 82.8 bits (203), Expect = 3e-16, Method: Compositional matrix adjust.
Identities = 63/225 (28%), Positives = 117/225 (52%), Gaps = 12/225 (5%)
Frame = +2
Query: 205 DAEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILLSFKTAYGKDLIKDLKSELSGNFEK 264
DA+ + KA+KG GTDE+A+I+ + +R+N Q + ++KT Y KD+ D++ + SG F++
Sbjct: 134 DAKQINKAVKGLGTDERALIEIICTRTNAQLTAMKEAYKTMYQKDVETDIEGDTSGPFKR 313
Query: 265 TILALMKTP----VLFDIYEIKEAIKGV--------GTDEACLIEILASRSNEHIRELNR 312
++ ++ FD + K+ + + GTDE+ ++ SRS +R +
Sbjct: 314 LLIGCLQANRPEGQEFDRNKAKQDAQALLEAGEKKWGTDESRFNVVIVSRSFPQLRATFQ 493
Query: 313 AYKAEFKKTLEEAIRSDTSGHFQRLLISLSQGNRDESTNVDMSLAQRDAQELYAAGENRL 372
Y K +E++I S+ SG + ++++ + R ++T+ A EL+ A + L
Sbjct: 494 EYAKLANKDIEDSISSEMSGDXKNGMLTVVRVIRSKATHF--------ATELHRAMKG-L 646
Query: 373 GTDESKFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGD 417
GTD+ V+ SR +V + E+QR + + I + SGD
Sbjct: 647 GTDDDTLVRVVASRCEVDMVQIKEEFQRNFKQTLYSFIVDDTSGD 781
Score = 34.3 bits (77), Expect = 0.13, Method: Compositional matrix adjust.
Identities = 19/68 (27%), Positives = 33/68 (48%)
Frame = +2
Query: 206 AEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILLSFKTAYGKDLIKDLKSELSGNFEKT 265
A L +AMKG GTD+ ++ + SR QI F+ + + L + + SG++
Sbjct: 614 ATELHRAMKGLGTDDDTLVRVVASRCEVDMVQIKEEFQRNFKQTLYSFIVDDTSGDYRLM 793
Query: 266 ILALMKTP 273
+ L+ P
Sbjct: 794 LCNLIGQP 817
>06659
Length = 776
Score = 164 bits (416), Expect = 5e-41, Method: Compositional matrix adjust.
Identities = 98/223 (43%), Positives = 139/223 (62%), Gaps = 3/223 (1%)
Frame = -3
Query: 281 IKEAIKGVGTDEACLIEILASRSNEHIRELNRAYKAEFKKTLEEAIRSDTSGHFQRLLIS 340
+ +AI G GTDE CLI+I+ +R N+ ++E+ YK EF+ LEE +++DT G+F+RL+IS
Sbjct: 774 LHDAISGAGTDEKCLIDIMCTRDNDEMKEIKEKYKEEFESELEEDLQADTGGYFRRLMIS 595
Query: 341 LSQGNRD--ESTNVDMSLAQRDAQELYAAGENRLGTDESKFNAVLCSRSRAHLVAVFNEY 398
L G RD + A DAQ+ AGEN GT+E+ NA+LC S A L +Y
Sbjct: 594 LCVGGRDYDNWWXANEDKAVEDAQKFLEAGENAWGTEEADMNAILCRTSPAQLCKTIEKY 415
Query: 399 QRMT-GRDIEKSICREMSGDLEEGMLAVVKCLKNTPAFFAERLNKAMRGAGTKDRTLIRI 457
+ +T G+ +E+SI E S DL +G LA+V+ ++ P +FA RLN G GT D LIRI
Sbjct: 414 EELTEGKTMEESIRSECSDDLXDGYLAIVESARSMPRYFARRLNDCFSGLGTSDNDLIRI 235
Query: 458 MVSRSETDLLDIRSEYKRMYGKSLYHDISGDTSGDYRKILLKI 500
+VSRSE DL I+ Y+ MY K L + + GDY+++LL I
Sbjct: 234 IVSRSEVDLEAIKQAYEEMYEKPLTEAVESECGGDYKRLLLAI 106
Score = 50.8 bits (120), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 57/233 (24%), Positives = 109/233 (46%), Gaps = 15/233 (6%)
Frame = -3
Query: 209 LRKAMKGFGTDEQAIIDCLGSRSNKQRQQILLSFKTAYGKDLIKDLKSELSGNFEKTILA 268
L A+ G GTDE+ +ID + +R N + ++I +K + +L +DL+++ G F + +++
Sbjct: 774 LHDAISGAGTDEKCLIDIMCTRDNDEMKEIKEKYKEEFESELEEDLQADTGGYFRRLMIS 595
Query: 269 LMKTPVLFDIYEIKEAIKGV--------------GTDEACLIEILASRSNEHIRELNRAY 314
L +D + K V GT+EA + IL S + + Y
Sbjct: 594 LCVGGRDYDNWWXANEDKAVEDAQKFLEAGENAWGTEEADMNAILCRTSPAQLCKTIEKY 415
Query: 315 KAEFK-KTLEEAIRSDTSGHFQRLLISLSQGNRDESTNVDMSLAQRDAQELYAAGENRLG 373
+ + KT+EE+IRS+ S +++ + R S+ + A+ L LG
Sbjct: 414 EELTEGKTMEESIRSECSDDLXDGYLAIVESAR--------SMPRYFARRLNDCFSG-LG 262
Query: 374 TDESKFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDLEEGMLAVV 426
T ++ ++ SRS L A+ Y+ M + + +++ E GD + +LA++
Sbjct: 261 TSDNDLIRIIVSRSEVDLEAIKQAYEEMYEKPLTEAVESECGGDYKRLLLAIL 103
Score = 37.0 bits (84), Expect = 0.019, Method: Compositional matrix adjust.
Identities = 24/67 (35%), Positives = 42/67 (62%), Gaps = 1/67 (1%)
Frame = -3
Query: 440 LNKAMRGAGTKDRTLIRIMVSRSETDLLDIRSEYKRMYGKSLYHDISGDTSGDYRKILLK 499
L+ A+ GAGT ++ LI IM +R ++ +I+ +YK + L D+ DT G +R++++
Sbjct: 774 LHDAISGAGTDEKCLIDIMCTRDNDEMKEIKEKYKEEFESELEEDLQADTGGYFRRLMIS 595
Query: 500 IC-GGND 505
+C GG D
Sbjct: 594 LCVGGRD 574
>36934
Length = 667
Score = 133 bits (335), Expect = 2e-31, Method: Compositional matrix adjust.
Identities = 77/218 (35%), Positives = 129/218 (59%), Gaps = 1/218 (0%)
Frame = +3
Query: 205 DAEVLRKAMKGFG-TDEQAIIDCLGSRSNKQRQQILLSFKTAYGKDLIKDLKSELSGNFE 263
DAE L KAM G G T E +++ + RSN QRQ + +K Y +DL + L+SEL+G+FE
Sbjct: 27 DAERLHKAMSGMGVTHEDTVLEIIIKRSNSQRQTLKKKYKEMYKRDLAEHLQSELTGDFE 206
Query: 264 KTILALMKTPVLFDIYEIKEAIKGVGTDEACLIEILASRSNEHIRELNRAYKAEFKKTLE 323
+ IL L+ PV +D + + +A+ G+GT+E LI IL + + + + + YK + + L+
Sbjct: 207 ELILGLLMPPVEYDAFCLNKAVDGLGTNEDVLIGILCTANPKELSSVKEVYKKTYGEDLD 386
Query: 324 EAIRSDTSGHFQRLLISLSQGNRDESTNVDMSLAQRDAQELYAAGENRLGTDESKFNAVL 383
AI+ DTSG F+ LL++LS+G RD+S +V+ A++DAQ+L + + G F +
Sbjct: 387 SAIKGDTSGGFEDLLLALSRGERDQSKSVNEKEAKQDAQKLCPDKK*KTGHG**NFQYID 566
Query: 384 CSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDLEEG 421
++ + A F EY+++ R C ++S + +G
Sbjct: 567 DKENKQQMKATFVEYEKLRVR-----ACWKLSKNHHQG 665
Score = 70.9 bits (172), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 46/147 (31%), Positives = 75/147 (51%)
Frame = +3
Query: 357 AQRDAQELYAAGENRLGTDESKFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSG 416
A DA+ L+ A T E ++ RS + + +Y+ M RD+ + + E++G
Sbjct: 18 AAEDAERLHKAMSGMGVTHEDTVLEIIIKRSNSQRQTLKKKYKEMYKRDLAEHLQSELTG 197
Query: 417 DLEEGMLAVVKCLKNTPAFFAERLNKAMRGAGTKDRTLIRIMVSRSETDLLDIRSEYKRM 476
D EE +L ++ AF LNKA+ G GT + LI I+ + + +L ++ YK+
Sbjct: 198 DFEELILGLLMPPVEYDAFC---LNKAVDGLGTNEDVLIGILCTANPKELSSVKEVYKKT 368
Query: 477 YGKSLYHDISGDTSGDYRKILLKICGG 503
YG+ L I GDTSG + +LL + G
Sbjct: 369 YGEDLDSAIKGDTSGGFEDLLLALSRG 449
>22178
Length = 655
Score = 114 bits (286), Expect = 7e-26, Method: Compositional matrix adjust.
Identities = 72/157 (45%), Positives = 98/157 (62%), Gaps = 6/157 (3%)
Frame = +1
Query: 352 VDMSLAQRDAQELYAAG---ENRLGTDESKFNAVL--CSRSRAHLVAV-FNEYQRMTGRD 405
VD ++A ++A ELY AG + R G + + ++V + H V N Q GR
Sbjct: 1 VDPTIAMQEAHELYKAG*KGKRRDGRGDVQPHSVPEELRATAGHF*RVQANLRQGHRGRH 180
Query: 406 IEKSICREMSGDLEEGMLAVVKCLKNTPAFFAERLNKAMRGAGTKDRTLIRIMVSRSETD 465
E ++ G L LA+V+ +NTPA+FAERL K+M+GAGT D+ LIR +VSRSE D
Sbjct: 181 QE*DEW-QLGGGL---FLAIVRVARNTPAYFAERLYKSMKGAGTNDKALIRAIVSRSEND 348
Query: 466 LLDIRSEYKRMYGKSLYHDISGDTSGDYRKILLKICG 502
L I+ E++RMYGK+L I GDTSGDY+KILL +CG
Sbjct: 349 LGFIKQEFQRMYGKTLASYIKGDTSGDYKKILLALCG 459
Score = 45.1 bits (105), Expect(2) = 3e-08, Method: Compositional matrix adjust.
Identities = 24/82 (29%), Positives = 45/82 (54%)
Frame = +1
Query: 260 GNFEKTILALMKTPVLFDIYEIKEAIKGVGTDEACLIEILASRSNEHIRELNRAYKAEFK 319
G F + TP F + +++KG GT++ LI + SRS + + + ++ +
Sbjct: 211 GLFLAIVRVARNTPAYFA-ERLYKSMKGAGTNDKALIRAIVSRSENDLGFIKQEFQRMYG 387
Query: 320 KTLEEAIRSDTSGHFQRLLISL 341
KTL I+ DTSG ++++L++L
Sbjct: 388 KTLASYIKGDTSGDYKKILLAL 453
Score = 30.8 bits (68), Expect(2) = 3e-08, Method: Compositional matrix adjust.
Identities = 17/50 (34%), Positives = 27/50 (54%)
Frame = +2
Query: 214 KGFGTDEQAIIDCLGSRSNKQRQQILLSFKTAYGKDLIKDLKSELSGNFE 263
+ GTDE+ L R+ Q + +++ GKD+ +KSE+SGN E
Sbjct: 59 ESVGTDEETFNRILCLRNYGQLRATFDAYRQISGKDIEDAIKSEMSGNLE 208
Score = 48.5 bits (114), Expect = 5e-06, Method: Compositional matrix adjust.
Identities = 28/68 (41%), Positives = 41/68 (60%)
Frame = +1
Query: 202 PLRDAEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILLSFKTAYGKDLIKDLKSELSGN 261
P AE L K+MKG GT+++A+I + SRS I F+ YGK L +K + SG+
Sbjct: 250 PAYFAERLYKSMKGAGTNDKALIRAIVSRSENDLGFIKQEFQRMYGKTLASYIKGDTSGD 429
Query: 262 FEKTILAL 269
++K +LAL
Sbjct: 430 YKKILLAL 453
Score = 31.6 bits (70), Expect = 0.70, Method: Compositional matrix adjust.
Identities = 18/50 (36%), Positives = 28/50 (56%)
Frame = +2
Query: 286 KGVGTDEACLIEILASRSNEHIRELNRAYKAEFKKTLEEAIRSDTSGHFQ 335
+ VGTDE IL R+ +R AY+ K +E+AI+S+ SG+ +
Sbjct: 59 ESVGTDEETFNRILCLRNYGQLRATFDAYRQISGKDIEDAIKSEMSGNLE 208
>17882
Length = 489
Score = 60.1 bits (144), Expect(2) = 1e-18, Method: Compositional matrix adjust.
Identities = 32/64 (50%), Positives = 43/64 (67%)
Frame = -1
Query: 439 RLNKAMRGAGTKDRTLIRIMVSRSETDLLDIRSEYKRMYGKSLYHDISGDTSGDYRKILL 498
RL++ + GT D LIRI+VSRSE DL DI+ Y Y K+L ++ DTSGDY+++LL
Sbjct: 369 RLHQVL---GTNDSRLIRIIVSRSEIDLQDIKDVYLSKYKKTLESAVASDTSGDYKRLLL 199
Query: 499 KICG 502
I G
Sbjct: 198 AIVG 187
Score = 51.2 bits (121), Expect(2) = 1e-18, Method: Compositional matrix adjust.
Identities = 20/44 (45%), Positives = 32/44 (72%)
Frame = -2
Query: 402 TGRDIEKSICREMSGDLEEGMLAVVKCLKNTPAFFAERLNKAMR 445
G+D+ SI EMSGD E G+ A+V+C+KN P +FA++L+ ++
Sbjct: 488 AGKDLLSSISSEMSGDFETGLRAIVRCMKNRPEYFADKLHDCIK 357
Score = 52.8 bits (125), Expect(2) = 7e-10, Method: Compositional matrix adjust.
Identities = 23/54 (42%), Positives = 41/54 (75%)
Frame = -1
Query: 288 VGTDEACLIEILASRSNEHIRELNRAYKAEFKKTLEEAIRSDTSGHFQRLLISL 341
+GT+++ LI I+ SRS ++++ Y +++KKTLE A+ SDTSG ++RLL+++
Sbjct: 354 LGTNDSRLIRIIVSRSEIDLQDIKDVYLSKYKKTLESAVASDTSGDYKRLLLAI 193
Score = 28.5 bits (62), Expect(2) = 7e-10, Method: Compositional matrix adjust.
Identities = 11/25 (44%), Positives = 19/25 (76%)
Frame = -2
Query: 247 GKDLIKDLKSELSGNFEKTILALMK 271
GKDL+ + SE+SG+FE + A+++
Sbjct: 485 GKDLLSSISSEMSGDFETGLRAIVR 411
Score = 32.7 bits (73), Expect = 0.39, Method: Compositional matrix adjust.
Identities = 16/55 (29%), Positives = 31/55 (56%)
Frame = -1
Query: 372 LGTDESKFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDLEEGMLAVV 426
LGT++S+ ++ SRS L + + Y + +E ++ + SGD + +LA+V
Sbjct: 354 LGTNDSRLIRIIVSRSEIDLQDIKDVYLSKYKKTLESAVASDTSGDYKRLLLAIV 190
>12136
Length = 445
Score = 87.4 bits (215), Expect = 1e-17, Method: Compositional matrix adjust.
Identities = 47/106 (44%), Positives = 66/106 (62%), Gaps = 7/106 (6%)
Frame = +3
Query: 250 LIKDLKSELSGNFEKTILALMKTPVLFDIYEIKEAIKGVGTDEACLIEILASRSNEHIRE 309
LI+++K ELSG++++ ++AL P +D + IKEAI G GTDE L+EIL +R+N I+E
Sbjct: 3 LIEEIKGELSGDYKELVMALFVAPAEYDAWCIKEAIYGPGTDEMALMEILMTRTNAQIKE 182
Query: 310 LNRAYKAEFK-------KTLEEAIRSDTSGHFQRLLISLSQGNRDE 348
L Y + +E+ I D SG F+RLLIS SQG R E
Sbjct: 183 LRSIYPSVLNDHYHGRTPKIEQDIEDDCSGDFKRLLISASQGGRFE 320
>29756
Length = 496
Score = 64.7 bits (156), Expect = 8e-11, Method: Compositional matrix adjust.
Identities = 35/74 (47%), Positives = 46/74 (62%), Gaps = 1/74 (1%)
Frame = +3
Query: 198 PGFDPLRDAEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILLSFKTAYGKDLIKDL-KS 256
P F+ D + LRKAMKGFGTDE+AIID LG R++ QRQ + L +K + K +
Sbjct: 258 PRFNAEEDVQKLRKAMKGFGTDEKAIIDILGYRTSDQRQNLKLMYKNLFWKRFGAGF*RV 437
Query: 257 ELSGNFEKTILALM 270
+G FE +LALM
Sbjct: 438 N*AGAFEDAMLALM 479
>13827
Length = 483
Score = 64.3 bits (155), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 28/59 (47%), Positives = 42/59 (71%)
Frame = -1
Query: 445 RGAGTKDRTLIRIMVSRSETDLLDIRSEYKRMYGKSLYHDISGDTSGDYRKILLKICGG 503
RG GT DRTLIR++V+R E D+ I+ E++ YG++L + D SGDYR+++L + GG
Sbjct: 444 RGMGTDDRTLIRVVVTRCEVDMKQIKQEFQNRYGQALEAFVRDDISGDYRRLMLALVGG 268
Score = 45.4 bits (106), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 17/59 (28%), Positives = 38/59 (64%)
Frame = -1
Query: 286 KGVGTDEACLIEILASRSNEHIRELNRAYKAEFKKTLEEAIRSDTSGHFQRLLISLSQG 344
+G+GTD+ LI ++ +R ++++ + ++ + + LE +R D SG ++RL+++L G
Sbjct: 444 RGMGTDDRTLIRVVVTRCEVDMKQIKQEFQNRYGQALEAFVRDDISGDYRRLMLALVGG 268
Score = 37.7 bits (86), Expect = 0.011, Method: Compositional matrix adjust.
Identities = 17/57 (29%), Positives = 35/57 (61%)
Frame = -1
Query: 214 KGFGTDEQAIIDCLGSRSNKQRQQILLSFKTAYGKDLIKDLKSELSGNFEKTILALM 270
+G GTD++ +I + +R +QI F+ YG+ L ++ ++SG++ + +LAL+
Sbjct: 444 RGMGTDDRTLIRVVVTRCEVDMKQIKQEFQNRYGQALEAFVRDDISGDYRRLMLALV 274
Score = 30.8 bits (68), Expect = 1.3, Method: Compositional matrix adjust.
Identities = 16/55 (29%), Positives = 29/55 (52%)
Frame = -1
Query: 372 LGTDESKFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDLEEGMLAVV 426
+GTD+ V+ +R + + E+Q G+ +E + ++SGD MLA+V
Sbjct: 438 MGTDDRTLIRVVVTRCEVDMKQIKQEFQNRYGQALEAFVRDDISGDYRRLMLALV 274
>07233
Length = 1497
Score = 28.5 bits (62), Expect = 6.1, Method: Compositional matrix adjust.
Identities = 11/39 (28%), Positives = 22/39 (56%)
Frame = -3
Query: 378 KFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSG 416
+F AVL + + +V +F EY + T + C++++G
Sbjct: 1027 EFPAVLVNVQQKQIVGMFREYXKPTVNPVLTEFCKQLTG 911
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000361308 | hsapiens_gene_ensembl | Annexin A11
(Annexin-11) (Annexin XI) (Calcyclin-associated annexin 50) (CAP-50)
(56 kDa autoantigen). [Source:Uniprot/SWISSPROT;Acc:P50995]
(505 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
32521 252 3e-67
06659 164 5e-41
36934 133 2e-31
22178 114 7e-26
17882 60 1e-18
12136 87 1e-17
29756 65 8e-11
13827 64 1e-10
07233 28 6.1
>32521
Length = 1241
Score = 252 bits (643), Expect = 3e-67, Method: Compositional matrix adjust.
Identities = 125/270 (46%), Positives = 179/270 (66%)
Frame = +2
Query: 233 KQRQQILLSFKTAYGKDLIKDLKSELSGNFEKTILALMKTPVLFDIYEIKEAIKGVGTDE 292
+QR++I L++KT +GKDL K+L ELSGNF+ + ++ P FD +I +A+KG+GTDE
Sbjct: 2 EQRREINLTYKTMFGKDLGKELSGELSGNFKTLCVEMLLGPAEFDAKQINKAVKGLGTDE 181
Query: 293 ACLIEILASRSNEHIRELNRAYKAEFKKTLEEAIRSDTSGHFQRLLISLSQGNRDESTNV 352
LIEI+ +R+N + + AYK ++K +E I DTSG F+RLLI Q NR E
Sbjct: 182 RALIEIICTRTNAQLTAMKEAYKTMYQKDVETDIEGDTSGPFKRLLIGCLQANRPEGQEF 361
Query: 353 DMSLAQRDAQELYAAGENRLGTDESKFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKSICR 412
D + A++DAQ L AGE + GTDES+FN V+ SRS L A F EY ++ +DIE SI
Sbjct: 362 DRNKAKQDAQALLEAGEKKWGTDESRFNVVIVSRSFPQLRATFQEYAKLANKDIEDSISS 541
Query: 413 EMSGDLEEGMLAVVKCLKNTPAFFAERLNKAMRGAGTKDRTLIRIMVSRSETDLLDIRSE 472
EMSGD + GML VV+ +++ FA L++AM+G GT D TL+R++ SR E D++ I+ E
Sbjct: 542 EMSGDXKNGMLTVVRVIRSKATHFATELHRAMKGLGTDDDTLVRVVASRCEVDMVQIKEE 721
Query: 473 YKRMYGKSLYHDISGDTSGDYRKILLKICG 502
++R + ++LY I DTSGDYR +L + G
Sbjct: 722 FQRNFKQTLYSFIVDDTSGDYRLMLCNLIG 811
Score = 82.8 bits (203), Expect = 3e-16, Method: Compositional matrix adjust.
Identities = 63/225 (28%), Positives = 117/225 (52%), Gaps = 12/225 (5%)
Frame = +2
Query: 205 DAEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILLSFKTAYGKDLIKDLKSELSGNFEK 264
DA+ + KA+KG GTDE+A+I+ + +R+N Q + ++KT Y KD+ D++ + SG F++
Sbjct: 134 DAKQINKAVKGLGTDERALIEIICTRTNAQLTAMKEAYKTMYQKDVETDIEGDTSGPFKR 313
Query: 265 TILALMKTP----VLFDIYEIKEAIKGV--------GTDEACLIEILASRSNEHIRELNR 312
++ ++ FD + K+ + + GTDE+ ++ SRS +R +
Sbjct: 314 LLIGCLQANRPEGQEFDRNKAKQDAQALLEAGEKKWGTDESRFNVVIVSRSFPQLRATFQ 493
Query: 313 AYKAEFKKTLEEAIRSDTSGHFQRLLISLSQGNRDESTNVDMSLAQRDAQELYAAGENRL 372
Y K +E++I S+ SG + ++++ + R ++T+ A EL+ A + L
Sbjct: 494 EYAKLANKDIEDSISSEMSGDXKNGMLTVVRVIRSKATHF--------ATELHRAMKG-L 646
Query: 373 GTDESKFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGD 417
GTD+ V+ SR +V + E+QR + + I + SGD
Sbjct: 647 GTDDDTLVRVVASRCEVDMVQIKEEFQRNFKQTLYSFIVDDTSGD 781
Score = 34.3 bits (77), Expect = 0.13, Method: Compositional matrix adjust.
Identities = 19/68 (27%), Positives = 33/68 (48%)
Frame = +2
Query: 206 AEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILLSFKTAYGKDLIKDLKSELSGNFEKT 265
A L +AMKG GTD+ ++ + SR QI F+ + + L + + SG++
Sbjct: 614 ATELHRAMKGLGTDDDTLVRVVASRCEVDMVQIKEEFQRNFKQTLYSFIVDDTSGDYRLM 793
Query: 266 ILALMKTP 273
+ L+ P
Sbjct: 794 LCNLIGQP 817
>06659
Length = 776
Score = 164 bits (416), Expect = 5e-41, Method: Compositional matrix adjust.
Identities = 98/223 (43%), Positives = 139/223 (62%), Gaps = 3/223 (1%)
Frame = -3
Query: 281 IKEAIKGVGTDEACLIEILASRSNEHIRELNRAYKAEFKKTLEEAIRSDTSGHFQRLLIS 340
+ +AI G GTDE CLI+I+ +R N+ ++E+ YK EF+ LEE +++DT G+F+RL+IS
Sbjct: 774 LHDAISGAGTDEKCLIDIMCTRDNDEMKEIKEKYKEEFESELEEDLQADTGGYFRRLMIS 595
Query: 341 LSQGNRD--ESTNVDMSLAQRDAQELYAAGENRLGTDESKFNAVLCSRSRAHLVAVFNEY 398
L G RD + A DAQ+ AGEN GT+E+ NA+LC S A L +Y
Sbjct: 594 LCVGGRDYDNWWXANEDKAVEDAQKFLEAGENAWGTEEADMNAILCRTSPAQLCKTIEKY 415
Query: 399 QRMT-GRDIEKSICREMSGDLEEGMLAVVKCLKNTPAFFAERLNKAMRGAGTKDRTLIRI 457
+ +T G+ +E+SI E S DL +G LA+V+ ++ P +FA RLN G GT D LIRI
Sbjct: 414 EELTEGKTMEESIRSECSDDLXDGYLAIVESARSMPRYFARRLNDCFSGLGTSDNDLIRI 235
Query: 458 MVSRSETDLLDIRSEYKRMYGKSLYHDISGDTSGDYRKILLKI 500
+VSRSE DL I+ Y+ MY K L + + GDY+++LL I
Sbjct: 234 IVSRSEVDLEAIKQAYEEMYEKPLTEAVESECGGDYKRLLLAI 106
Score = 50.8 bits (120), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 57/233 (24%), Positives = 109/233 (46%), Gaps = 15/233 (6%)
Frame = -3
Query: 209 LRKAMKGFGTDEQAIIDCLGSRSNKQRQQILLSFKTAYGKDLIKDLKSELSGNFEKTILA 268
L A+ G GTDE+ +ID + +R N + ++I +K + +L +DL+++ G F + +++
Sbjct: 774 LHDAISGAGTDEKCLIDIMCTRDNDEMKEIKEKYKEEFESELEEDLQADTGGYFRRLMIS 595
Query: 269 LMKTPVLFDIYEIKEAIKGV--------------GTDEACLIEILASRSNEHIRELNRAY 314
L +D + K V GT+EA + IL S + + Y
Sbjct: 594 LCVGGRDYDNWWXANEDKAVEDAQKFLEAGENAWGTEEADMNAILCRTSPAQLCKTIEKY 415
Query: 315 KAEFK-KTLEEAIRSDTSGHFQRLLISLSQGNRDESTNVDMSLAQRDAQELYAAGENRLG 373
+ + KT+EE+IRS+ S +++ + R S+ + A+ L LG
Sbjct: 414 EELTEGKTMEESIRSECSDDLXDGYLAIVESAR--------SMPRYFARRLNDCFSG-LG 262
Query: 374 TDESKFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDLEEGMLAVV 426
T ++ ++ SRS L A+ Y+ M + + +++ E GD + +LA++
Sbjct: 261 TSDNDLIRIIVSRSEVDLEAIKQAYEEMYEKPLTEAVESECGGDYKRLLLAIL 103
Score = 37.0 bits (84), Expect = 0.019, Method: Compositional matrix adjust.
Identities = 24/67 (35%), Positives = 42/67 (62%), Gaps = 1/67 (1%)
Frame = -3
Query: 440 LNKAMRGAGTKDRTLIRIMVSRSETDLLDIRSEYKRMYGKSLYHDISGDTSGDYRKILLK 499
L+ A+ GAGT ++ LI IM +R ++ +I+ +YK + L D+ DT G +R++++
Sbjct: 774 LHDAISGAGTDEKCLIDIMCTRDNDEMKEIKEKYKEEFESELEEDLQADTGGYFRRLMIS 595
Query: 500 IC-GGND 505
+C GG D
Sbjct: 594 LCVGGRD 574
>36934
Length = 667
Score = 133 bits (335), Expect = 2e-31, Method: Compositional matrix adjust.
Identities = 77/218 (35%), Positives = 129/218 (59%), Gaps = 1/218 (0%)
Frame = +3
Query: 205 DAEVLRKAMKGFG-TDEQAIIDCLGSRSNKQRQQILLSFKTAYGKDLIKDLKSELSGNFE 263
DAE L KAM G G T E +++ + RSN QRQ + +K Y +DL + L+SEL+G+FE
Sbjct: 27 DAERLHKAMSGMGVTHEDTVLEIIIKRSNSQRQTLKKKYKEMYKRDLAEHLQSELTGDFE 206
Query: 264 KTILALMKTPVLFDIYEIKEAIKGVGTDEACLIEILASRSNEHIRELNRAYKAEFKKTLE 323
+ IL L+ PV +D + + +A+ G+GT+E LI IL + + + + + YK + + L+
Sbjct: 207 ELILGLLMPPVEYDAFCLNKAVDGLGTNEDVLIGILCTANPKELSSVKEVYKKTYGEDLD 386
Query: 324 EAIRSDTSGHFQRLLISLSQGNRDESTNVDMSLAQRDAQELYAAGENRLGTDESKFNAVL 383
AI+ DTSG F+ LL++LS+G RD+S +V+ A++DAQ+L + + G F +
Sbjct: 387 SAIKGDTSGGFEDLLLALSRGERDQSKSVNEKEAKQDAQKLCPDKK*KTGHG**NFQYID 566
Query: 384 CSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDLEEG 421
++ + A F EY+++ R C ++S + +G
Sbjct: 567 DKENKQQMKATFVEYEKLRVR-----ACWKLSKNHHQG 665
Score = 70.9 bits (172), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 46/147 (31%), Positives = 75/147 (51%)
Frame = +3
Query: 357 AQRDAQELYAAGENRLGTDESKFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSG 416
A DA+ L+ A T E ++ RS + + +Y+ M RD+ + + E++G
Sbjct: 18 AAEDAERLHKAMSGMGVTHEDTVLEIIIKRSNSQRQTLKKKYKEMYKRDLAEHLQSELTG 197
Query: 417 DLEEGMLAVVKCLKNTPAFFAERLNKAMRGAGTKDRTLIRIMVSRSETDLLDIRSEYKRM 476
D EE +L ++ AF LNKA+ G GT + LI I+ + + +L ++ YK+
Sbjct: 198 DFEELILGLLMPPVEYDAFC---LNKAVDGLGTNEDVLIGILCTANPKELSSVKEVYKKT 368
Query: 477 YGKSLYHDISGDTSGDYRKILLKICGG 503
YG+ L I GDTSG + +LL + G
Sbjct: 369 YGEDLDSAIKGDTSGGFEDLLLALSRG 449
>22178
Length = 655
Score = 114 bits (286), Expect = 7e-26, Method: Compositional matrix adjust.
Identities = 72/157 (45%), Positives = 98/157 (62%), Gaps = 6/157 (3%)
Frame = +1
Query: 352 VDMSLAQRDAQELYAAG---ENRLGTDESKFNAVL--CSRSRAHLVAV-FNEYQRMTGRD 405
VD ++A ++A ELY AG + R G + + ++V + H V N Q GR
Sbjct: 1 VDPTIAMQEAHELYKAG*KGKRRDGRGDVQPHSVPEELRATAGHF*RVQANLRQGHRGRH 180
Query: 406 IEKSICREMSGDLEEGMLAVVKCLKNTPAFFAERLNKAMRGAGTKDRTLIRIMVSRSETD 465
E ++ G L LA+V+ +NTPA+FAERL K+M+GAGT D+ LIR +VSRSE D
Sbjct: 181 QE*DEW-QLGGGL---FLAIVRVARNTPAYFAERLYKSMKGAGTNDKALIRAIVSRSEND 348
Query: 466 LLDIRSEYKRMYGKSLYHDISGDTSGDYRKILLKICG 502
L I+ E++RMYGK+L I GDTSGDY+KILL +CG
Sbjct: 349 LGFIKQEFQRMYGKTLASYIKGDTSGDYKKILLALCG 459
Score = 45.1 bits (105), Expect(2) = 3e-08, Method: Compositional matrix adjust.
Identities = 24/82 (29%), Positives = 45/82 (54%)
Frame = +1
Query: 260 GNFEKTILALMKTPVLFDIYEIKEAIKGVGTDEACLIEILASRSNEHIRELNRAYKAEFK 319
G F + TP F + +++KG GT++ LI + SRS + + + ++ +
Sbjct: 211 GLFLAIVRVARNTPAYFA-ERLYKSMKGAGTNDKALIRAIVSRSENDLGFIKQEFQRMYG 387
Query: 320 KTLEEAIRSDTSGHFQRLLISL 341
KTL I+ DTSG ++++L++L
Sbjct: 388 KTLASYIKGDTSGDYKKILLAL 453
Score = 30.8 bits (68), Expect(2) = 3e-08, Method: Compositional matrix adjust.
Identities = 17/50 (34%), Positives = 27/50 (54%)
Frame = +2
Query: 214 KGFGTDEQAIIDCLGSRSNKQRQQILLSFKTAYGKDLIKDLKSELSGNFE 263
+ GTDE+ L R+ Q + +++ GKD+ +KSE+SGN E
Sbjct: 59 ESVGTDEETFNRILCLRNYGQLRATFDAYRQISGKDIEDAIKSEMSGNLE 208
Score = 48.5 bits (114), Expect = 5e-06, Method: Compositional matrix adjust.
Identities = 28/68 (41%), Positives = 41/68 (60%)
Frame = +1
Query: 202 PLRDAEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILLSFKTAYGKDLIKDLKSELSGN 261
P AE L K+MKG GT+++A+I + SRS I F+ YGK L +K + SG+
Sbjct: 250 PAYFAERLYKSMKGAGTNDKALIRAIVSRSENDLGFIKQEFQRMYGKTLASYIKGDTSGD 429
Query: 262 FEKTILAL 269
++K +LAL
Sbjct: 430 YKKILLAL 453
Score = 31.6 bits (70), Expect = 0.70, Method: Compositional matrix adjust.
Identities = 18/50 (36%), Positives = 28/50 (56%)
Frame = +2
Query: 286 KGVGTDEACLIEILASRSNEHIRELNRAYKAEFKKTLEEAIRSDTSGHFQ 335
+ VGTDE IL R+ +R AY+ K +E+AI+S+ SG+ +
Sbjct: 59 ESVGTDEETFNRILCLRNYGQLRATFDAYRQISGKDIEDAIKSEMSGNLE 208
>17882
Length = 489
Score = 60.1 bits (144), Expect(2) = 1e-18, Method: Compositional matrix adjust.
Identities = 32/64 (50%), Positives = 43/64 (67%)
Frame = -1
Query: 439 RLNKAMRGAGTKDRTLIRIMVSRSETDLLDIRSEYKRMYGKSLYHDISGDTSGDYRKILL 498
RL++ + GT D LIRI+VSRSE DL DI+ Y Y K+L ++ DTSGDY+++LL
Sbjct: 369 RLHQVL---GTNDSRLIRIIVSRSEIDLQDIKDVYLSKYKKTLESAVASDTSGDYKRLLL 199
Query: 499 KICG 502
I G
Sbjct: 198 AIVG 187
Score = 51.2 bits (121), Expect(2) = 1e-18, Method: Compositional matrix adjust.
Identities = 20/44 (45%), Positives = 32/44 (72%)
Frame = -2
Query: 402 TGRDIEKSICREMSGDLEEGMLAVVKCLKNTPAFFAERLNKAMR 445
G+D+ SI EMSGD E G+ A+V+C+KN P +FA++L+ ++
Sbjct: 488 AGKDLLSSISSEMSGDFETGLRAIVRCMKNRPEYFADKLHDCIK 357
Score = 52.8 bits (125), Expect(2) = 7e-10, Method: Compositional matrix adjust.
Identities = 23/54 (42%), Positives = 41/54 (75%)
Frame = -1
Query: 288 VGTDEACLIEILASRSNEHIRELNRAYKAEFKKTLEEAIRSDTSGHFQRLLISL 341
+GT+++ LI I+ SRS ++++ Y +++KKTLE A+ SDTSG ++RLL+++
Sbjct: 354 LGTNDSRLIRIIVSRSEIDLQDIKDVYLSKYKKTLESAVASDTSGDYKRLLLAI 193
Score = 28.5 bits (62), Expect(2) = 7e-10, Method: Compositional matrix adjust.
Identities = 11/25 (44%), Positives = 19/25 (76%)
Frame = -2
Query: 247 GKDLIKDLKSELSGNFEKTILALMK 271
GKDL+ + SE+SG+FE + A+++
Sbjct: 485 GKDLLSSISSEMSGDFETGLRAIVR 411
Score = 32.7 bits (73), Expect = 0.39, Method: Compositional matrix adjust.
Identities = 16/55 (29%), Positives = 31/55 (56%)
Frame = -1
Query: 372 LGTDESKFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDLEEGMLAVV 426
LGT++S+ ++ SRS L + + Y + +E ++ + SGD + +LA+V
Sbjct: 354 LGTNDSRLIRIIVSRSEIDLQDIKDVYLSKYKKTLESAVASDTSGDYKRLLLAIV 190
>12136
Length = 445
Score = 87.4 bits (215), Expect = 1e-17, Method: Compositional matrix adjust.
Identities = 47/106 (44%), Positives = 66/106 (62%), Gaps = 7/106 (6%)
Frame = +3
Query: 250 LIKDLKSELSGNFEKTILALMKTPVLFDIYEIKEAIKGVGTDEACLIEILASRSNEHIRE 309
LI+++K ELSG++++ ++AL P +D + IKEAI G GTDE L+EIL +R+N I+E
Sbjct: 3 LIEEIKGELSGDYKELVMALFVAPAEYDAWCIKEAIYGPGTDEMALMEILMTRTNAQIKE 182
Query: 310 LNRAYKAEFK-------KTLEEAIRSDTSGHFQRLLISLSQGNRDE 348
L Y + +E+ I D SG F+RLLIS SQG R E
Sbjct: 183 LRSIYPSVLNDHYHGRTPKIEQDIEDDCSGDFKRLLISASQGGRFE 320
>29756
Length = 496
Score = 64.7 bits (156), Expect = 8e-11, Method: Compositional matrix adjust.
Identities = 35/74 (47%), Positives = 46/74 (62%), Gaps = 1/74 (1%)
Frame = +3
Query: 198 PGFDPLRDAEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILLSFKTAYGKDLIKDL-KS 256
P F+ D + LRKAMKGFGTDE+AIID LG R++ QRQ + L +K + K +
Sbjct: 258 PRFNAEEDVQKLRKAMKGFGTDEKAIIDILGYRTSDQRQNLKLMYKNLFWKRFGAGF*RV 437
Query: 257 ELSGNFEKTILALM 270
+G FE +LALM
Sbjct: 438 N*AGAFEDAMLALM 479
>13827
Length = 483
Score = 64.3 bits (155), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 28/59 (47%), Positives = 42/59 (71%)
Frame = -1
Query: 445 RGAGTKDRTLIRIMVSRSETDLLDIRSEYKRMYGKSLYHDISGDTSGDYRKILLKICGG 503
RG GT DRTLIR++V+R E D+ I+ E++ YG++L + D SGDYR+++L + GG
Sbjct: 444 RGMGTDDRTLIRVVVTRCEVDMKQIKQEFQNRYGQALEAFVRDDISGDYRRLMLALVGG 268
Score = 45.4 bits (106), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 17/59 (28%), Positives = 38/59 (64%)
Frame = -1
Query: 286 KGVGTDEACLIEILASRSNEHIRELNRAYKAEFKKTLEEAIRSDTSGHFQRLLISLSQG 344
+G+GTD+ LI ++ +R ++++ + ++ + + LE +R D SG ++RL+++L G
Sbjct: 444 RGMGTDDRTLIRVVVTRCEVDMKQIKQEFQNRYGQALEAFVRDDISGDYRRLMLALVGG 268
Score = 37.7 bits (86), Expect = 0.011, Method: Compositional matrix adjust.
Identities = 17/57 (29%), Positives = 35/57 (61%)
Frame = -1
Query: 214 KGFGTDEQAIIDCLGSRSNKQRQQILLSFKTAYGKDLIKDLKSELSGNFEKTILALM 270
+G GTD++ +I + +R +QI F+ YG+ L ++ ++SG++ + +LAL+
Sbjct: 444 RGMGTDDRTLIRVVVTRCEVDMKQIKQEFQNRYGQALEAFVRDDISGDYRRLMLALV 274
Score = 30.8 bits (68), Expect = 1.3, Method: Compositional matrix adjust.
Identities = 16/55 (29%), Positives = 29/55 (52%)
Frame = -1
Query: 372 LGTDESKFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDLEEGMLAVV 426
+GTD+ V+ +R + + E+Q G+ +E + ++SGD MLA+V
Sbjct: 438 MGTDDRTLIRVVVTRCEVDMKQIKQEFQNRYGQALEAFVRDDISGDYRRLMLALV 274
>07233
Length = 1497
Score = 28.5 bits (62), Expect = 6.1, Method: Compositional matrix adjust.
Identities = 11/39 (28%), Positives = 22/39 (56%)
Frame = -3
Query: 378 KFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSG 416
+F AVL + + +V +F EY + T + C++++G
Sbjct: 1027 EFPAVLVNVQQKQIVGMFREYXKPTVNPVLTEFCKQLTG 911
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000348965 | hsapiens_gene_ensembl | Dynein heavy
chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1)
(Dynein heavy chain 1, cytoplasmic 1).
[Source:Uniprot/SWISSPROT;Acc:Q14204]
(4646 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
28569 253 1e-66
35960 243 1e-63
23257 197 1e-58
20410 132 4e-40
28658 149 3e-35
14519 147 1e-34
37041 107 9e-23
24890 99 3e-20
19780 89 5e-17
12392 86 3e-16
36750 60 2e-15
27572 83 3e-15
20622 79 5e-14
07275 74 1e-12
32781 71 1e-11
35288 58 1e-07
06548 56 4e-07
20268 44 0.002
13559 42 0.008
25583 40 0.021
31256 34 1.5
30327 34 1.6
15303 34 1.7
00810 33 2.9
>28569
Length = 475
Score = 253 bits (646), Expect = 1e-66, Method: Compositional matrix adjust.
Identities = 121/156 (77%), Positives = 135/156 (86%)
Frame = -3
Query: 3436 MIRDLEASIARYKEEYAVLISEAQAIKADLAAVEAKVNRSTALLKSLSAERERWEKTSET 3495
+I+ LE SI +YKEEYAVLIS+AQAIKADLAAVEAKV RS ALL SL E++RWE SET
Sbjct: 470 LIQGLEQSIGKYKEEYAVLISQAQAIKADLAAVEAKVERSVALLNSLGNEKQRWEAGSET 291
Query: 3496 FKNQMSTIAGDCLLSAAFIAYAGYFDQQMRQNLFTTWSHHLQQANIQFRTDIARTEYLSN 3555
FK QM+TI GD LLSAAF+AYAGYFDQQMRQNLF W +HLQ A IQFR D+ARTEYLSN
Sbjct: 290 FKQQMATIIGDVLLSAAFMAYAGYFDQQMRQNLFGNWCNHLQLAMIQFRPDLARTEYLSN 111
Query: 3556 ADERLRWQASSLPADDLCTENAIMLKRFNRYPLIID 3591
ADERL WQA++LP D+LCTENAIMLKRFNRYPLI+D
Sbjct: 110 ADERLNWQANALPTDELCTENAIMLKRFNRYPLIVD 3
>35960
Length = 734
Score = 243 bits (620), Expect = 1e-63, Method: Compositional matrix adjust.
Identities = 129/248 (52%), Positives = 168/248 (67%), Gaps = 4/248 (1%)
Frame = +1
Query: 3868 FNRVARGMLHQDHITFAMLLARIKLKGTVGEPTYDAEFQHFLRGNEIVLSAGSTPRIQGL 3927
+ RV GML++D ITFA+ L RI L+G E TYD EF HFLR E +L STP +
Sbjct: 1 YGRVGCGMLYEDRITFAIQLCRIHLEGMASEGTYDVEFNHFLRSQEGLLMDKSTPLLLAS 180
Query: 3928 TVEQAE-AVVRLSCLPAFKD-LIAKVQADEQFGIWLDSSSPEQ--TVPYLWSEETPATPI 3983
+ + V +SC P+ +++ + G W + P Q P LWSE+ T I
Sbjct: 181 PSNRIQPCCVSVSCQPSETC*TKSRITLSSRLG-W---TVPSQRWDFPPLWSEDKAQTAI 348
Query: 3984 GQAIHRLLLIQAFRPDRLLAMAHMFVSTNLGESFMSIMEQPLDLTHIVGTEVKPNTPVLM 4043
G+++H LL+IQA RPDRL+AMA +FV LG F+ I E+ L+L+ IV TE+K +TPVLM
Sbjct: 349 GKSVHGLLVIQALRPDRLIAMARIFVEKTLGSDFVHITEKELNLSLIVETEIKGSTPVLM 528
Query: 4044 CSVPGYDASGHVEDLAAEQNTQITSIAIGSAEGFNQADKAINTAVKSGRWVMLKNVHLAP 4103
CS PGYD S V+DLAAE + Q+TSIAIGSAEGF+QA+KAIN++ KSGRWV+LKNVHLAP
Sbjct: 529 CSAPGYDPSSRVDDLAAELSKQMTSIAIGSAEGFSQAEKAINSSSKSGRWVLLKNVHLAP 708
Query: 4104 GWLMQLEK 4111
WL+QLE+
Sbjct: 709 QWLVQLER 732
>23257
Length = 1984
Score = 197 bits (502), Expect(2) = 1e-58, Method: Compositional matrix adjust.
Identities = 99/170 (58%), Positives = 127/170 (74%), Gaps = 2/170 (1%)
Frame = -2
Query: 4479 VSDFSERIKQLQNISLAAASGGAKELKNIHVCLGGLFVPEAYITATRQYVAQANSWSLEE 4538
++DFS R+KQLQ I A+ + ++ELKN+++ LGG+F+PEAYITATRQ+VAQAN+WSLEE
Sbjct: 1863 ITDFSLRVKQLQAIVQASQASSSRELKNLNMWLGGMFIPEAYITATRQFVAQANNWSLEE 1684
Query: 4539 LCLEVNVTTSQGATLDACSFGVTGLKLQGATCNNNKLSLSNAISTALPLTQLRWVKQTNT 4598
L L+V V + LD CSFGV GLKLQGA C+NNKL LS IST L LT LRW+K +
Sbjct: 1683 LYLDVLVQDGKPQALDDCSFGVLGLKLQGAACSNNKLQLSTTISTDLKLTVLRWIKVDGS 1504
Query: 4599 EKKASVVTLPVYLNFTRADLIFTVDFEIATKEDPR--SFYERGVAVLCTE 4646
+ + VTLPVYLN TR L+FTVDF+ A K + FYERGVA++C++
Sbjct: 1503 KNMDNRVTLPVYLNATRDQLLFTVDFDCAEKTAGKDHGFYERGVALICSD 1354
Score = 50.8 bits (120), Expect(2) = 1e-58, Method: Composition-based stats.
Identities = 20/38 (52%), Positives = 31/38 (81%)
Frame = -3
Query: 4440 GKKKQTNYLRTLINELVKGILPRSWSHYTVPAGMTVIQ 4477
G+ + ++ R+++ +LVKGI+P+SW YTVPAG+TVIQ
Sbjct: 1979 GENEAHHHHRSMMADLVKGIIPKSWRRYTVPAGLTVIQ 1866
>20410
Length = 754
Score = 132 bits (332), Expect(2) = 4e-40, Method: Composition-based stats.
Identities = 63/141 (44%), Positives = 86/141 (60%)
Frame = -2
Query: 1879 LVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKALGHQLGRFVLVFNCDETFDF 1938
LV TPLTDRCY T+ AL LGG+P GPAGTGKTE+ K L + + +VFNC + D+
Sbjct: 393 LVITPLTDRCYRTLFGALHLHLGGAPEGPAGTGKTETTKDLAKAVAKQCVVFNCSDGLDY 214
Query: 1939 QAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQVQCIQEALREHSNPNYDKTSAPIT 1998
A+G+ F GL GAW CFDEFNR++ +LS V+QQ+ IQ + S+ T
Sbjct: 213 IALGKFFKGLASCGAWSCFDEFNRIDLEVLSVVAQQILTIQRGINSGSD----------T 64
Query: 1999 CELLNKQVKVSPDMAIFITMN 2019
++++ P ++FITMN
Sbjct: 63 LLFEGTEIRLDPTCSVFITMN 1
Score = 54.3 bits (129), Expect(2) = 4e-40, Method: Compositional matrix adjust.
Identities = 28/79 (35%), Positives = 41/79 (51%)
Frame = -1
Query: 1805 RRKLEHLITELVHQRDVTRSLIKSKIDNAKSFEWLSQMRFYFDPKQTDVLQQLSIQMANA 1864
R L+ +I VH RDV L K +I + F WLSQ+R+Y++ Q+ +M N+
Sbjct: 598 RVTLQAMIVLEVHSRDVLAELCKVQISSELDFNWLSQLRYYWEEG------QMITRMINS 437
Query: 1865 KFNYGFEYLGVQDKLVQTP 1883
YG+EYLG + P
Sbjct: 436 MLKYGYEYLGNSGRTXHHP 380
>28658
Length = 552
Score = 149 bits (375), Expect = 3e-35, Method: Compositional matrix adjust.
Identities = 75/149 (50%), Positives = 99/149 (66%)
Frame = +3
Query: 1955 GCFDEFNRLEERMLSAVSQQVQCIQEALREHSNPNYDKTSAPITCELLNKQVKVSPDMAI 2014
CFDEFNR++ +LS V+QQ+ I +A ++ + + ++ + P A+
Sbjct: 3 ACFDEFNRIDIEVLSVVAQQITTIHKAQQQRLDRSI----------FEGVELVLRPSCAV 152
Query: 2015 FITMNPGYAGRSNLPDNLKKLFRSLAMTKPDRQLIAQVMLYSQGFRTAEVLANKIVPFFK 2074
FITMNPGYAGR+ LPDNLK LFR +AM PD LIA++ L+S GF A LA KIV FK
Sbjct: 153 FITMNPGYAGRTELPDNLKALFRPVAMMVPDYALIAEISLFSFGFSDARNLAKKIVTTFK 332
Query: 2075 LCDEQLSSQSHYDFGLRALKSVLVSAGNV 2103
L EQLSSQ HYDFG+RA+KSV+ +AGN+
Sbjct: 333 LSSEQLSSQDHYDFGMRAVKSVISAAGNL 419
>14519
Length = 945
Score = 147 bits (370), Expect = 1e-34, Method: Compositional matrix adjust.
Identities = 72/208 (34%), Positives = 117/208 (56%), Gaps = 1/208 (0%)
Frame = -3
Query: 2909 LVLFNEVLDHVLRIDRIFRQPQGHLLLIGVSGAGKTTLSRFVAWMNGLSVYQIKVHRKYT 2968
LV F + + H+L+I RI R P+GH LL+GV G+GK +L+R +++ G +QI + R Y
Sbjct: 682 LVFFKDAMIHLLKISRIIRTPRGHALLVGVGGSGKQSLTRLSSFIAGYKTFQITLTRSYN 503
Query: 2969 GEDFDEDLRTVLRRSGCKNEKIAFIMDESNVLDSGFLERMNTLLANGEVPGLFEGDEYAT 3028
+ +DL+ + R +G + + I FI + + D GFLE +N +L++G V LF DE
Sbjct: 502 VSNLLDDLKNLYRTAGQEGKGITFIFTDQEIKDEGFLEYLNNMLSSGVVANLFARDEMDE 323
Query: 3029 LMTQCKEGAQKE-GLMLDSHEELYKWFTSQVIRNLHVVFTMNPSSEGLKDRAATSPALFN 3087
++ + + E S+E LY+++ S+V NLHV +P E + RA P L +
Sbjct: 322 ILGELVPVMKXEFPRRPPSNENLYEYYLSRVRNNLHVTLCFSPVGEKFRQRALKFPGLIS 143
Query: 3088 RCVLNWFGDWSTEALYQVGKEFTSKMDL 3115
C ++WF W +AL V F ++ D+
Sbjct: 142 GCTMDWFQRWPKDALIAVADHFLAEFDI 59
>37041
Length = 350
Score = 107 bits (268), Expect = 9e-23, Method: Composition-based stats.
Identities = 52/105 (49%), Positives = 71/105 (67%)
Frame = -2
Query: 2275 WTDGLFTHVLRKIIDSVRGELQKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLS 2334
WTDG+F+ + R+ + +GE W+V DG VD W+ENLNSVLDDNK LTL NG+R+
Sbjct: 310 WTDGIFSTLWRRTHKTKKGE---HVWLVLDGPVDAIWIENLNSVLDDNKTLTLANGDRIP 140
Query: 2335 LPPNVRIMFEVQDLKYATLATVSRCGMVWFSEDVLSTDMIFNNFL 2379
+ PN +I+FEV ++ A+ ATVSR GMV+ S +L D I +L
Sbjct: 139 MAPNCKIIFEVHNIDNASPATVSRNGMVFMSSSILDWDPILQGWL 5
>24890
Length = 425
Score = 99.4 bits (246), Expect = 3e-20, Method: Compositional matrix adjust.
Identities = 48/79 (60%), Positives = 61/79 (77%), Gaps = 2/79 (2%)
Frame = -2
Query: 4277 SFDSEFKLACKVD--GHKDIQMPDGIRREEFVQWVELLPDTQTPSWLGLPNNAERVLLTT 4334
S+DS F L VD K I MPDG+RRE+FVQ+V+ L QTPSWLGLPNNAE+VLLTT
Sbjct: 280 SYDSSFVLVRNVDDISGKHIGMPDGVRREQFVQFVDNLEGPQTPSWLGLPNNAEKVLLTT 101
Query: 4335 QGVDMISKMLKMQMLEDED 4353
G DMI+++++MQ+LE+ D
Sbjct: 100 LGSDMIARLMRMQLLEEAD 44
>19780
Length = 1009
Score = 88.6 bits (218), Expect = 5e-17, Method: Compositional matrix adjust.
Identities = 68/263 (25%), Positives = 117/263 (44%), Gaps = 29/263 (11%)
Frame = +1
Query: 2482 QIEQLERYIQRYLVYAILWSLSGDSRLKMRAELGEYIRRITT---VPLPTAPNIPIIDYE 2538
Q+ ++ I+ + +++ +WS++ R + E++R L + DY
Sbjct: 34 QMGRINELIEPWFIFSFVWSVAATCDNDGRVKFSEWLREKMAEKKCKLKFPEEGLVYDYM 213
Query: 2539 VSISG-------------------EWSPWQAKVPQIEVETHKVAAPDVVVPTLDTVRHEA 2579
+ +G +W W +P EV + D++VPT+DT+R
Sbjct: 214 LDDAGISSTDRDDIEEEEAVHKEVQWRNWMHGLPTYEVAPDTKFS-DILVPTIDTIRSAY 390
Query: 2580 LLYTWLAEHKPLVLCGPPGSGKTMTLFSAL------RALPDMEVVGLNFSSATTPELLLK 2633
++ L+ +K ++ GP G+GKTMT+ L +PD V S+ T +L+
Sbjct: 391 IIGMLLSNNKTVLSVGPTGTGKTMTISDKLTRNMAKEYIPDFIVFSAKTSANQTQDLI-- 564
Query: 2634 TFDHYCEYRRTPNGVVLAPVQLGKWLVLFCDEINLPDMDKYGTQRVISFIRQMVEHGGFY 2693
D + RR GV P LGK+ + F D++N+P + YG Q I IRQ ++ G+Y
Sbjct: 565 --DGKLDKRR--KGVFGPP--LGKYFIFFIDDLNMPAREVYGAQPPIELIRQWMDFNGWY 726
Query: 2694 -RTSDQTWVKLERIQFVGACNPP 2715
R + + L + F A PP
Sbjct: 727 DRKAIGDFRNLVDVNFACAMGPP 795
>12392
Length = 445
Score = 86.3 bits (212), Expect = 3e-16, Method: Compositional matrix adjust.
Identities = 51/144 (35%), Positives = 76/144 (52%)
Frame = +3
Query: 1745 YQAQLVVLSAQIAWSENVETALSSMGGGGDAAPLHSVLSNVEVTLNVLADSVLMEQPPLR 1804
+ +Q+ +L Q+ W+ + E AL++ D + + LN+L D + +
Sbjct: 30 FPSQIGLLGLQMIWTRDSEEALNN--ARVDKKIMTNTNQKFLDLLNMLIDQTTRDLTKIE 203
Query: 1805 RRKLEHLITELVHQRDVTRSLIKSKIDNAKSFEWLSQMRFYFDPKQTDVLQQLSIQMANA 1864
R K E LIT VHQ+D+ L++ I + FEWL Q RFY+ + TD Q I + +
Sbjct: 204 RTKFETLITIHVHQKDIFDDLVRMHIKSVNDFEWLKQSRFYY-KEDTD---QCVISITDV 371
Query: 1865 KFNYGFEYLGVQDKLVQTPLTDRC 1888
F Y E+LG D+LV TPLTDRC
Sbjct: 372 DFLYMNEFLGCTDRLVITPLTDRC 443
>36750
Length = 1066
Score = 60.1 bits (144), Expect(2) = 2e-15, Method: Compositional matrix adjust.
Identities = 46/197 (23%), Positives = 86/197 (43%), Gaps = 17/197 (8%)
Frame = -1
Query: 2659 LVLFCDEINLPDMDKYGTQRVISFIRQMVEHGGFYRTSDQT-WVKLERIQFVGACNPPTD 2717
+ +F D+IN+P ++++G Q +RQ++E+GGFY + + +QF+ A P
Sbjct: 787 MTVFLDDINMPIINEWGDQVANEIVRQLMENGGFYSLEKPGDFTTIADVQFLAAMIQPGG 608
Query: 2718 PGRKPLSHRFLRHVPVVYVDYPGPASLTQIYGTFNRAML---------------RLIPSL 2762
GR + R R + P S+ +I+ + R++P
Sbjct: 607 -GRNDIPQRLKRQFVIFNCTLPSNTSIDKIFSVIGQGHFCKERGFSNKVIEMVKRIVPVT 431
Query: 2763 RTYAEPLTAAMVEFYTMSQERFTQDTQPHYIYSPREMTRWVRGIFEALRPLETLPVEG-L 2821
R + M+ + +F HYI++ R+++R +G+ + T+ E L
Sbjct: 430 RRLWQLTKIKMLP----TPAKF------HYIFNLRDLSRIWQGMLKT--SSSTVNSEKVL 287
Query: 2822 IRIWAHEALRLFQDRLV 2838
+ +W HE R+ DR V
Sbjct: 286 MYLWKHECCRVIADRCV 236
Score = 43.1 bits (100), Expect(2) = 2e-15, Method: Composition-based stats.
Identities = 26/78 (33%), Positives = 45/78 (57%), Gaps = 2/78 (2%)
Frame = -2
Query: 2567 VVVPTLDTVRHEALLYTWLAEHKPLVLCGPPGSGKTMTLFSALRAL-PDMEVV-GLNFSS 2624
++VP +D VR E L+ T ++K ++L G G+ KT+ + + P+ + +NFSS
Sbjct: 1056 ILVPNVDNVRTEFLIDTISKQNKAVLLIGEQGTAKTVMINGYMGLYNPEFHLSETVNFSS 877
Query: 2625 ATTPELLLKTFDHYCEYR 2642
ATTP + +T + Y + R
Sbjct: 876 ATTPLMYQRTIESYVDKR 823
>27572
Length = 403
Score = 82.8 bits (203), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 44/123 (35%), Positives = 69/123 (56%), Gaps = 5/123 (4%)
Frame = +2
Query: 1564 ETQRFQSISTEFLALMKKVSKSPLVMDVLNIQGVQRSLERLADLLGKIQKALGEYLERER 1623
+++RF I T+F L+ +V K+ +D N + LE L L +KAL EYLE +R
Sbjct: 2 DSKRFDGIDTDFKELVGQVEKTKNCVDATNQPKLYERLETLQHNLALCEKALAEYLETKR 181
Query: 1624 SSFPRFYFVGDEDLLEIIGNSKNVAKLQKHFKKMFAGVSSIILNEDNS-----VVLGISS 1678
+FPRFYFV DLL+I+ N N + +H K+F ++ + +D+S V G+ S
Sbjct: 182 LAFPRFYFVSSSDLLDILSNGNNPVSVARHLTKLFDSMAQLKFEKDSSGNEIKVATGMHS 361
Query: 1679 REG 1681
++G
Sbjct: 362 KDG 370
>20622
Length = 448
Score = 78.6 bits (192), Expect = 5e-14, Method: Composition-based stats.
Identities = 49/161 (30%), Positives = 76/161 (47%), Gaps = 4/161 (2%)
Frame = -2
Query: 4159 RTFSSIPVS--RICKSPNERARLYFLLAWFHAIIQERLRYAPLGWSKKYEFGESDLRSAC 4216
RT++ I I P + LY + + H I+QER ++ PLGW+ YEF SD ++
Sbjct: 441 RTYAGITQDYLDISNMPQWKPMLYGV-GFLHTIVQERRKFGPLGWNIPYEFNTSDYNASV 265
Query: 4217 DTVDTWLDDT--AKGRQNISPDKIPWSALKTLMAQSIYGGRVDNEFDQRLLNTFLERLFT 4274
V LDD KG + W ++ + + YGGRV ++FD+RLLNTF F
Sbjct: 264 QFVQNHLDDMDIKKG--------VNWICVRYMFGEIQYGGRVTDDFDKRLLNTFCRVWFG 109
Query: 4275 TRSFDSEFKLACKVDGHKDIQMPDGIRREEFVQWVELLPDT 4315
F F +K +P + E+ +++ LP +
Sbjct: 108 ENMFTPAFNF------YKGYVIPKCAKINEYHEYINSLPSS 4
>07275
Length = 1513
Score = 74.3 bits (181), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 56/208 (26%), Positives = 98/208 (47%), Gaps = 12/208 (5%)
Frame = +2
Query: 4448 LRTLINELVKGILPRSWSHYTVPAGMTVIQWVSDFSERIKQLQ----NISLAAASGGAKE 4503
+ L N L ++P +WS P+ T+ W +D +RIK+L+ + L AA
Sbjct: 2 MEALSNALFLDVVPDNWSKRAYPSLFTLGLWYADLLQRIKELETWTSDFQLPAA------ 163
Query: 4504 LKNIHVCLGGLFVPEAYITATRQYVAQANSWSLEELCLEVNVTTSQ-----GATLDACSF 4558
V LGG F P++++TA Q +A+ N W L+ + L+ +VT G +
Sbjct: 164 -----VWLGGFFNPQSFLTAIMQQMARKNEWPLDRMVLQCDVTKKSRDDMAGPPREGAY- 325
Query: 4559 GVTGLKLQGATCNNNKLSLSNA-ISTALPLTQLRWVKQTNTEKK--ASVVTLPVYLNFTR 4615
V GL ++GA + ++ A + P+ + ++K +++ ++ + PVY +R
Sbjct: 326 -VHGLYMEGARWDTQTGMMAEARLKELAPIMPVLFIKAIPVDRQDVRNIYSCPVYKTKSR 502
Query: 4616 ADLIFTVDFEIATKEDPRSFYERGVAVL 4643
F F + TKE P + GVA+L
Sbjct: 503 GP-TFVWTFNLKTKEKPSKWILGGVAIL 583
>32781
Length = 632
Score = 70.9 bits (172), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 43/137 (31%), Positives = 67/137 (48%), Gaps = 7/137 (5%)
Frame = -3
Query: 3482 LSAERERWEKTSETFKNQMSTIAGDCLLSAAFIAYAGYFDQQMRQNLFTTWSHHLQQANI 3541
L++E RW + + F+ T+ GD L+ AF++Y G F + R LF T HL
Sbjct: 498 LASENVRWADSIQQFRINEQTLPGDVLMITAFVSYVGSFTXRYRTELFET---HLTPFLK 328
Query: 3542 QFRTDIARTEYLS------NADERLRWQASSLPADDLCTENAIMLKRFNRYPLIIDPSGQ 3595
+ + +E L + + W LP+D + TENA +L R+PL+IDP Q
Sbjct: 327 GLKYPVPVSEGLDPLTMLVDDADIAGWNNEGLPSDRMSTENATILTSCERWPLMIDPQLQ 148
Query: 3596 ATEFIMNEY-KDRKITR 3611
++I +Y D K+ R
Sbjct: 147 GIKWIKTKYGADLKVVR 97
>35288
Length = 370
Score = 57.8 bits (138), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 35/128 (27%), Positives = 65/128 (50%)
Frame = +3
Query: 3482 LSAERERWEKTSETFKNQMSTIAGDCLLSAAFIAYAGYFDQQMRQNLFTTWSHHLQQANI 3541
L E +RW + ++ + LL+AAFI Y + +R+ W + A+
Sbjct: 3 LDGEYQRWNEQVGELTKELQELPLRALLAAAFITYLPSAPEDLRREYMKAWMDAIGIAHF 182
Query: 3542 QFRTDIARTEYLSNADERLRWQASSLPADDLCTENAIMLKRFNRYPLIIDPSGQATEFIM 3601
R +LS E+L W+A LP+D+L ENA+++ + ++ P ++DPS +AT ++
Sbjct: 183 DLR------RFLSTESEQLTWKAEGLPSDELSMENALVILQSSQRPFLVDPSSRATXWLK 344
Query: 3602 NEYKDRKI 3609
K+ ++
Sbjct: 345 VHMKNNRL 368
>06548
Length = 1130
Score = 55.8 bits (133), Expect = 4e-07, Method: Compositional matrix adjust.
Identities = 49/195 (25%), Positives = 84/195 (43%), Gaps = 10/195 (5%)
Frame = -2
Query: 4460 LPRSWSHYTVPAGMTVIQWVSDFSERIKQLQNISLAAASGGAKELKNIHVCLGGLFVPEA 4519
+P +W + + T+ W +D +R Q E + + + G F P+
Sbjct: 1048 VPNTWKKISWESA-TLGFWFTDLLDRNTQFNAWLF--------EGRPVSFWMTGFFNPQG 896
Query: 4520 YITATRQYVAQAN-SWSLEELCLEVNVTTSQGATLDAC---SFGVTGLKLQGATCNNNKL 4575
++TA RQ + +A+ W+L+ + L+ +VT + + V GL L GA
Sbjct: 895 FLTAMRQEITRAHKGWALDTVILDNDVTRMMKEDVHSPPGEGVYVHGLFLDGAGWERRNA 716
Query: 4576 SL----SNAISTALPLTQLRWVKQTNTEKKAS--VVTLPVYLNFTRADLIFTVDFEIATK 4629
L + + T LP+ + TN EK+ S + PVY R DL + + T
Sbjct: 715 RLIEPTAKVLYTLLPVVH---ISATNVEKQRSMNLYECPVYKKPKRTDLTYIFPLMLKTN 545
Query: 4630 EDPRSFYERGVAVLC 4644
++P + RGV +LC
Sbjct: 544 KNPDYWTLRGVGLLC 500
>20268
Length = 416
Score = 43.9 bits (102), Expect = 0.002, Method: Composition-based stats.
Identities = 20/68 (29%), Positives = 39/68 (57%)
Frame = -1
Query: 1613 KALGEYLERERSSFPRFYFVGDEDLLEIIGNSKNVAKLQKHFKKMFAGVSSIILNEDNSV 1672
K+L YL+ +R +FPRFYFV D LL ++ ++ ++ H + +F + + L + +
Sbjct: 242 KSLMGYLDNKRRAFPRFYFVSDNILLALLSRPNDLDSVRPHLRSIFMQLHDVKLEKAHEH 63
Query: 1673 VLGISSRE 1680
+L +S +
Sbjct: 62 ILDDNSSD 39
>13559
Length = 1151
Score = 41.6 bits (96), Expect = 0.008, Method: Composition-based stats.
Identities = 23/59 (38%), Positives = 35/59 (59%), Gaps = 4/59 (6%)
Frame = -2
Query: 3585 RYPLIIDPSGQATEFIMNEYKD----RKITRTSFLDDAFRKNLESALRFGNPLLVQDVE 3639
++PLIIDP+GQA+ F+ Y+D I T ++ R + ALRFG PL++ +E
Sbjct: 1078 KWPLIIDPTGQASTFL--RYRDTNYINAIRPTDMEEERARMAILGALRFGKPLVLDMME 908
>25583
Length = 434
Score = 40.0 bits (92), Expect = 0.021, Method: Composition-based stats.
Identities = 16/43 (37%), Positives = 27/43 (62%)
Frame = -1
Query: 3163 KRGGRTMAITPRHYLDFINHYANLFHEKRSELEEQQMHLNVGL 3205
+R R+ +TP+ YL F+N Y N++ +K+ E+ E +N GL
Sbjct: 413 QRYRRSTHVTPKSYLSFLNSYKNVYKQKKDEIGELANRMNTGL 285
>31256
Length = 351
Score = 33.9 bits (76), Expect = 1.5, Method: Composition-based stats.
Identities = 15/39 (38%), Positives = 21/39 (53%)
Frame = -2
Query: 4606 TLPVYLNFTRADLIFTVDFEIATKEDPRSFYERGVAVLC 4644
T P+Y R DL + D + T + P + RGVA+LC
Sbjct: 200 TCPIYKKPRRTDLTYIADVMLRTTQSPDHWILRGVALLC 84
>30327
Length = 563
Score = 33.9 bits (76), Expect = 1.6, Method: Compositional matrix adjust.
Identities = 33/121 (27%), Positives = 57/121 (47%), Gaps = 11/121 (9%)
Frame = +1
Query: 3583 FNRYPLIIDPSGQATEFIMNEYKDRKITRTSFLDDAFRKNLESALRFGNPLLVQ----DV 3638
F RY D + + I + ++D+K+T T+F+D +K + + G P+ +Q
Sbjct: 1 FRRYKSTEDQTTHLAQVIEDAFQDQKVTLTAFID--LQKAFDKVWKDGLPVKLQRSGIHG 174
Query: 3639 ESYDPVLNPVLNREVR-----RTGGRVLITLG-DQDIDLSPS-FVIFLSTRDPTVEFPPD 3691
Y + NR R R G +VL+ G Q LSP+ F++F++ +F P+
Sbjct: 175 NMYRWTKAYLYNRRARVLVNGRYGRKVLLRQGVPQGGVLSPTLFILFMN------DFVPE 336
Query: 3692 L 3692
L
Sbjct: 337 L 339
>15303
Length = 479
Score = 33.9 bits (76), Expect = 1.7, Method: Composition-based stats.
Identities = 19/44 (43%), Positives = 25/44 (56%), Gaps = 1/44 (2%)
Frame = -3
Query: 4368 STSDGRPAWM-RTLHTTASNWLHLIPQTLSHLKRTVENIKDPLF 4410
S SDGR ++ LHT LHL+P + LKR V ++K LF
Sbjct: 360 SWSDGRYIFLIHLLHTVRLQNLHLLPHSPKRLKRVVLHVKHTLF 229
>00810
Length = 1431
Score = 33.1 bits (74), Expect = 2.9, Method: Compositional matrix adjust.
Identities = 48/187 (25%), Positives = 72/187 (38%), Gaps = 11/187 (5%)
Frame = -3
Query: 2573 DTVRHEALLYTWLAEHKPLVLCGPPGSGKTMTLFSALRALPDMEVVGLNFSSATTPELLL 2632
D RH +LL K ++L GPPG GKTM + A + L SS
Sbjct: 1372 DLFRHSSLLQP----PKGVLLHGPPGCGKTM-IAKATAKAAGARFINLQVSSLVD----- 1223
Query: 2633 KTFDHYCEYRRTPNGVVLAPVQLGKWLVLFCDEINLPDMDKYGTQRVISFIRQMV----E 2688
Y E ++ V ++L + ++F DEI+ SF+R E
Sbjct: 1222 ---KWYGESQKRAEAVFSLAIKL-QPTIIFIDEID-------------SFLRSRTSTDHE 1094
Query: 2689 HGGFYRTSDQT-WVKLE-----RIQFVGACNPPTDPGRKPLSHRFLRHVPVVY-VDYPGP 2741
+T + W L R+ +GA N P D + LR +P ++ + PGP
Sbjct: 1093 ATAMIKTQFMSFWDGLMTDPDCRVMVMGATNRPQD-----VDAAILRRMPSMFHIGLPGP 929
Query: 2742 ASLTQIY 2748
A I+
Sbjct: 928 AQRRSIF 908
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000011619 | hsapiens_gene_ensembl | Ran-binding
protein 9 (RanBP9) (RanBP7) (Ran-binding protein M) (RanBPM) (BPM90)
(BPM-L). [Source:Uniprot/SWISSPROT;Acc:Q96S59]
(729 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
28401 248 5e-66
18917 61 2e-09
20279 44 3e-04
>28401
Length = 448
Score = 248 bits (634), Expect = 5e-66, Method: Compositional matrix adjust.
Identities = 109/149 (73%), Positives = 132/149 (88%)
Frame = -2
Query: 282 GCCVNLINNTCFYTKNGHSLGIAFTDLPPNLYPTVGLQTPGEVVDANFGQHPFVFDIEDY 341
GCCVNLI+N+CFYTKNG +LG+AFT LPPNLYPTVGLQTPGEVV+ANFGQ PF+FDI +Y
Sbjct: 447 GCCVNLIDNSCFYTKNGVNLGVAFTALPPNLYPTVGLQTPGEVVEANFGQSPFIFDIREY 268
Query: 342 MREWRTKIQAQIDRFPIGDREGEWQTMIQKMVSSYLVHHGYCATAEAFARSTDQTVLEEL 401
MR+W K + I+RFP+ DR GEWQ ++Q++VS+YLVHHGYCATAE+F ++T Q + E+L
Sbjct: 267 MRDWHMKTKLNIERFPVTDRRGEWQQILQRLVSTYLVHHGYCATAESFCKATSQPIEEDL 88
Query: 402 ASIKNRQRIQKLVLAGRMGEAIETTQQLY 430
ASIK+RQRIQKLVL+GRMGEAIE TQQLY
Sbjct: 87 ASIKHRQRIQKLVLSGRMGEAIEFTQQLY 1
>18917
Length = 698
Score = 60.8 bits (146), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 38/131 (29%), Positives = 64/131 (48%), Gaps = 20/131 (15%)
Frame = -2
Query: 209 PAACGIYYFEVKIVSKGRDGYMGIGLSAQGVNMNRLPGWDKHSYGYHGDDGHSFCSSGTG 268
P + + YFE+++V ++GIG+ N++ GW + S GYH D+G ++ ++ +G
Sbjct: 475 PFSSHLSYFEMEVVKVSAKKHLGIGVVHAHYPANQMIGWRQSSLGYHADNGEAYQNTSSG 296
Query: 269 -QP----YGPTFTTGDVIGCCVNLINN--------------TCFYTKNGHSLGI-AFTDL 308
+P P F GDV+GC +++ T ++TKNGH L I F
Sbjct: 295 FRPTVTGIEPWFGKGDVVGCGIDMSKAKLKPDGSLVPQQTLTVYFTKNGHRLHIREFHYG 116
Query: 309 PPNLYPTVGLQ 319
LYP + +
Sbjct: 115 VEGLYPAINMH 83
>20279
Length = 636
Score = 43.5 bits (101), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 21/65 (32%), Positives = 34/65 (52%), Gaps = 2/65 (3%)
Frame = +2
Query: 219 VKIVSKGRDGYMGIGLSAQGVNMNRLPGWDKHSYGYHGDDGHSFC--SSGTGQPYGPTFT 276
+K++ G+ G + +G+ + R PGW+ +S HGDDG +C SS + F+
Sbjct: 383 IKVLHLGQKGTITLGIGPEKYPTQRQPGWESNSIALHGDDGKLYCQMSSSPSERVTTQFS 562
Query: 277 TGDVI 281
GD I
Sbjct: 563 VGDEI 577
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000362649 | hsapiens_gene_ensembl | Histone
deacetylase 1 (HD1). [Source:Uniprot/SWISSPROT;Acc:Q13547]
(482 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
07455 246 1e-65
11442 99 4e-21
29373 85 6e-17
03696 85 8e-17
27665 68 1e-11
08437 50 3e-06
26221 29 5.1
>07455
Length = 1702
Score = 246 bits (629), Expect = 1e-65, Method: Compositional matrix adjust.
Identities = 120/259 (46%), Positives = 173/259 (66%), Gaps = 1/259 (0%)
Frame = -1
Query: 116 GSVASAVKLNKQQTDIAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDI 175
+V +A L +Q +A+NW GG HHA++SEASGFCY+NDIVL IL L RVLY+D+
Sbjct: 1702 ATVTAAQALCDRQCQVAINWCGGWHHAQRSEASGFCYINDIVLGILTLRNQFSRVLYVDL 1523
Query: 176 DIHHGDGVEEAFYTTDRVMTVSFHKYGE-YFPGTGDLRDIGAGKGKYYAVNYPLRDGIDD 234
D+HHGDGVE AF TT V+TVSFHK+ +FPG+G + D+G+ GK++ VN P++DG+ D
Sbjct: 1522 DLHHGDGVENAFSTTSHVLTVSFHKHAAGFFPGSGGIEDVGSRGGKHFCVNVPMKDGLCD 1343
Query: 235 ESYEAIFKPVMSKVMEMFQPSAVVLQCGSDSLSGDRLGCFNLTIKGHAKCVEFVKSFNLP 294
+ A+FK VMS V E + P VV QCG+D L+GD + FNLT+ C+ + S+ LP
Sbjct: 1342 NEFLAVFKRVMSCVRETYNPEVVVCQCGADGLAGDPMSSFNLTLTSLRHCLYLLMSWKLP 1163
Query: 295 MLMLGGGGYTIRNVARCWTYETAVALDTEIPNELPYNDYFEYFGPDFKLHISPSNMTNQN 354
+L+LGGGGY N ARCW TA+ + ++P ++P + +F +GPD++L + N + N
Sbjct: 1162 LLLLGGGGYHHANTARCWASLTALTVGRKLPQDVPDHKFFMEYGPDYELTVXAGNRKDDN 983
Query: 355 TNEYLEKIKQRLFENLRML 373
T + L + + ENL+ +
Sbjct: 982 TVKNLASTCRVITENLQKI 926
>11442
Length = 783
Score = 99.0 bits (245), Expect = 4e-21, Method: Compositional matrix adjust.
Identities = 49/89 (55%), Positives = 57/89 (64%), Gaps = 1/89 (1%)
Frame = -3
Query: 300 GGGYTIRNVARCWTYETAVALDTEIPNELPYNDYFEYFGPDFKLHISPSN-MTNQNTNEY 358
G G +NVARCWTYETA+ LD +I N+LPYNDY YF PDF LH S N NT +Y
Sbjct: 691 GRGXHQKNVARCWTYETAILLDEQITNDLPYNDYLAYFAPDFSLHPDISTKQENLNTKQY 512
Query: 359 LEKIKQRLFENLRMLPHAPGVQMQAIPED 387
LE I+ ENL+ L AP VQM +P D
Sbjct: 511 LEYIRIATHENLKNLAFAPSVQMHDVPSD 425
Score = 66.6 bits (161), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 31/53 (58%), Positives = 36/53 (67%), Gaps = 8/53 (15%)
Frame = -1
Query: 269 DRLGCFNLTIKGHAKCVEFVKSFNLPMLMLGGGGYTIRNVAR--------CWT 313
DRLGCFNL++KGH +CV+ VK F LPML+LGGGGYT R CWT
Sbjct: 783 DRLGCFNLSVKGHGECVQVVKDFGLPMLVLGGGGYTKRTWLAAGPMRRPYCWT 625
>29373
Length = 589
Score = 85.1 bits (209), Expect = 6e-17, Method: Compositional matrix adjust.
Identities = 56/182 (30%), Positives = 86/182 (47%), Gaps = 2/182 (1%)
Frame = -3
Query: 101 PVFDGLFEFCQLSTGGSVASAVKLNKQQTDIAVNWAGGLHHAKKSEASGFCYVNDIVLAI 160
P GL + C+ TGG+V + + +A + GG HHA SG+C +ND+ +A
Sbjct: 515 PWSQGLVDRCRYETGGTVLTCQM--ALEHGLACSTGGGTHHAFPDHGSGYCLINDMAVAA 342
Query: 161 LELLKYHQ--RVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGK 218
+L+ RVL +D+D+H GDG F RV T S H FP D+ G
Sbjct: 341 AAMLQCCSVSRVLIVDLDVHQGDGTAMMFEADTRVFTFSMHCQNN-FPANKQDSDLDIG- 168
Query: 219 GKYYAVNYPLRDGIDDESYEAIFKPVMSKVMEMFQPSAVVLQCGSDSLSGDRLGCFNLTI 278
L +G++D+ Y + + +S +++ F+P V+ G D D LG LT
Sbjct: 167 ---------LSNGLEDKEYMLLLEGHLSWIVDTFRPDLVLYDAGVDPHVKDELGKLCLTD 15
Query: 279 KG 280
+G
Sbjct: 14 QG 9
>03696
Length = 1593
Score = 84.7 bits (208), Expect = 8e-17, Method: Compositional matrix adjust.
Identities = 63/230 (27%), Positives = 108/230 (46%), Gaps = 7/230 (3%)
Frame = -3
Query: 149 GFCYVNDIVLA-ILELLKYH-QRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGE-YF 205
GFC N+I +A + K+ +RVL +D D+HHG+ + FY V+ +S H+Y + YF
Sbjct: 1588 GFCIFNNIAIAAVYAQSKFGVKRVLILDWDVHHGNATQHMFYNDPSVLYISLHRYEKGYF 1409
Query: 206 PG--TGDLRDIGAGKGKYYAVNYPLRD-GIDDESYEAIFKPVMSKVMEMFQPSAVVLQCG 262
P DL IG G+G + +N P D + D Y A F ++ + F P V++ G
Sbjct: 1408 PDHPEADLHYIGEGEGTGFNINIPWMDETMGDAEYMAAFHRIIMPIAYEFAPELVLVSAG 1229
Query: 263 SDSLSGDRLGCFNLTIKGHAKCVEFVKSF-NLPMLMLGGGGYTIRNVARCWTYETAVALD 321
D+ GD LG F++ + + S N ++++ GGY + ++ T+V L
Sbjct: 1228 YDAAEGDVLGGFHVMPECFGHMTHMLTSLANGRVVLVLEGGYNVLALSLSMATCTSVLLG 1049
Query: 322 TEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTNEYLEKIKQRLFENLR 371
P +P +N + NT + +I+Q +++L+
Sbjct: 1048 DPCPPLVP----------------GTANSSACNTIRKVLEIQQPFWKSLK 947
>27665
Length = 370
Score = 67.8 bits (164), Expect = 1e-11, Method: Composition-based stats.
Identities = 36/113 (31%), Positives = 60/113 (53%), Gaps = 4/113 (3%)
Frame = +1
Query: 169 RVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGE-YFPGTGDLRD--IGAGKGKYYAVN 225
+VL +D D+HHG+ + FY V+ +S H+Y +FPG D +G +G+ + VN
Sbjct: 1 KVLILDWDVHHGNATQRMFYNDPSVLYISLHRYDRGFFPGLPDANSHFVGVDEGRGFNVN 180
Query: 226 YP-LRDGIDDESYEAIFKPVMSKVMEMFQPSAVVLQCGSDSLSGDRLGCFNLT 277
P + + + Y A F+ ++ + F P V++ G D+ GD LG + LT
Sbjct: 181 IPWTMERMGNAEYMAAFERIVMPIAYEFAPELVLVSAGFDAAVGDFLGGYKLT 339
>08437
Length = 1146
Score = 49.7 bits (117), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 21/67 (31%), Positives = 39/67 (58%)
Frame = +2
Query: 307 NVARCWTYETAVALDTEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTNEYLEKIKQRL 366
N ARCW TA+ + ++P ++P + +F +GPD++L + N + NT + L + +
Sbjct: 2 NTARCWASLTALTVGRKLPQDVPDHKFFMEYGPDYELTVQAGNRKDDNTVKNLASTCRVI 181
Query: 367 FENLRML 373
ENL+ +
Sbjct: 182 TENLQKI 202
>26221
Length = 720
Score = 28.9 bits (63), Expect = 5.1, Method: Compositional matrix adjust.
Identities = 12/34 (35%), Positives = 19/34 (55%)
Frame = +3
Query: 72 YIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDG 105
YIK RPD + ++SK + N+ DC ++ G
Sbjct: 102 YIKLPAINRPDGLKQHSKVILIVNIYTDCEIYRG 203
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000300249 | hsapiens_gene_ensembl |
Microtubule-associated protein RP/EB family member 2 (APC-binding
protein EB2) (End-binding protein 2) (EB2).
[Source:Uniprot/SWISSPROT;Acc:Q15555]
(327 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
02149 243 5e-65
06997 62 3e-10
28710 61 5e-10
09949 59 2e-09
11636 28 4.6
>02149
Length = 1269
Score = 243 bits (621), Expect = 5e-65, Method: Compositional matrix adjust.
Identities = 125/255 (49%), Positives = 159/255 (62%)
Frame = +3
Query: 44 MAVNVYSTSITQETMSRHDIIAWVNDIVSLNYTKVEQLCSGAAYCQFMDMLFPGCISLKK 103
MAVNV+STS T + +SRHDIIAWVND + +Y K+E+LC+GAAYCQFMDMLFPG ++LKK
Sbjct: 69 MAVNVHSTSCTSDNLSRHDIIAWVNDSLQTSYGKIEELCTGAAYCQFMDMLFPGTLALKK 248
Query: 104 VKFQAKLEHEYIHNFKLLQASFKRMNVDKVIPVEKLVKGRFQDNLDFIQWFKKFYDANYD 163
KF KLEHEYI NFKLLQ +F ++ VDKVIPVE+LVKGRFQDN +F+QWFK+F+DAN
Sbjct: 249 AKFNTKLEHEYIQNFKLLQNNFGKLGVDKVIPVERLVKGRFQDNFEFVQWFKRFFDANNK 428
Query: 164 GKEYDPVEARQGQDAIPPPDPGEQIFNLPKKSHHANXXXXXXXXXXXXXXXXXXXXXXXX 223
G +YDP+ AR G+ P G L K +
Sbjct: 429 GLDYDPLSARGGE-----PMGGANKGALNKAPSNRTAPPKTRVPPSRTTPARPAANNVRS 593
Query: 224 XXXXXXXXXXXXXDKDLETQVIQLNEQVHSLKLALEGVEKERDFYFGKLREIELLCQEHG 283
+E L ++ L + EG+EKERDFYFGKLR+IE++CQEH
Sbjct: 594 PMSKPTSNHAAGDSPMVE----DLRAELRQLTVEKEGLEKERDFYFGKLRDIEVICQEH- 758
Query: 284 QENDDLVQRLMDILY 298
E+D ++ +MDILY
Sbjct: 759 -EDDVSMKAIMDILY 800
>06997
Length = 583
Score = 62.0 bits (149), Expect = 3e-10, Method: Compositional matrix adjust.
Identities = 32/61 (52%), Positives = 44/61 (72%)
Frame = +1
Query: 238 KDLETQVIQLNEQVHSLKLALEGVEKERDFYFGKLREIELLCQEHGQENDDLVQRLMDIL 297
+DL +V Q+ L + EG+EKERDFYFGKLR+IE++CQEH E+D ++ +MDIL
Sbjct: 76 EDLRAEVCA---QLRQLTVEKEGLEKERDFYFGKLRDIEVICQEH--EDDVSMKAIMDIL 240
Query: 298 Y 298
Y
Sbjct: 241 Y 243
>28710
Length = 525
Score = 61.2 bits (147), Expect = 5e-10, Method: Compositional matrix adjust.
Identities = 30/59 (50%), Positives = 46/59 (77%), Gaps = 1/59 (1%)
Frame = -1
Query: 241 ETQVIQ-LNEQVHSLKLALEGVEKERDFYFGKLREIELLCQEHGQENDDLVQRLMDILY 298
+TQ+++ L ++ + L EG+EKERDFYFGKLR+IE++CQEH E+ D ++ ++DILY
Sbjct: 525 DTQMVEDLRAELRQMNLEKEGLEKERDFYFGKLRDIEIICQEH--EDSDTMKGILDILY 355
>09949
Length = 455
Score = 59.3 bits (142), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 29/52 (55%), Positives = 40/52 (76%)
Frame = -1
Query: 247 LNEQVHSLKLALEGVEKERDFYFGKLREIELLCQEHGQENDDLVQRLMDILY 298
L ++ L + EG+EKERDFYFGKLR+IE++CQEH E+D ++ +MDILY
Sbjct: 440 LRAELRQLTVEKEGLEKERDFYFGKLRDIEVICQEH--EDDVSMKAIMDILY 291
>11636
Length = 819
Score = 28.1 bits (61), Expect = 4.6, Method: Compositional matrix adjust.
Identities = 12/26 (46%), Positives = 19/26 (73%)
Frame = +1
Query: 247 LNEQVHSLKLALEGVEKERDFYFGKL 272
L +++ +LK L+G+EKE DF+ KL
Sbjct: 514 LEKEIXALKKGLQGIEKEVDFFKSKL 591
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000272317 | hsapiens_gene_ensembl | 40S ribosomal
protein S27a. [Source:Uniprot/SWISSPROT;Acc:P62979]
(156 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
00758 238 1e-63
03942 230 1e-61
04649 159 2e-59
04017 158 9e-40
13455 154 2e-38
34270 120 9e-31
08296 95 9e-21
24173 84 3e-17
02863 52 2e-16
25295 49 8e-07
14135 48 1e-06
34268 46 6e-06
13753 43 7e-05
22667 35 0.017
25348 28 2.2
24931 27 3.0
>00758
Length = 1050
Score = 238 bits (606), Expect = 1e-63, Method: Compositional matrix adjust.
Identities = 118/154 (76%), Positives = 122/154 (79%)
Frame = +1
Query: 1 MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYN 60
MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYN
Sbjct: 523 MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYN 702
Query: 61 IQKESTLHLVLRLRGGAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDENGKISRLRRE 120
IQKESTLHLVLRLRGGA DENGKI+RLRRE
Sbjct: 703 IQKESTLHLVLRLRGGAKKRKKKNYTTPKKSKHKKKKVKLAVLKYYKVDENGKITRLRRE 882
Query: 121 CPSDECGAGVFMASHFDRHYCGKCCLTYCFNKPE 154
CP+++CGAGVFMASHFDRHYCGKCCLTY FNKPE
Sbjct: 883 CPNEDCGAGVFMASHFDRHYCGKCCLTYVFNKPE 984
>03942
Length = 912
Score = 230 bits (587), Expect = 1e-61, Method: Compositional matrix adjust.
Identities = 115/154 (74%), Positives = 121/154 (78%)
Frame = +1
Query: 1 MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYN 60
MQIFVKTLTGKTITLEVEPSDTIENVKAK +DKEGIPPDQQRLIFAGKQLEDGRTLSDYN
Sbjct: 406 MQIFVKTLTGKTITLEVEPSDTIENVKAKSKDKEGIPPDQQRLIFAGKQLEDGRTLSDYN 585
Query: 61 IQKESTLHLVLRLRGGAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDENGKISRLRRE 120
IQKESTLHLVLRLRGGA D+NGKI+RLRRE
Sbjct: 586 IQKESTLHLVLRLRGGAKKRKKKNYTTPKKSKHKKKKVKLAVLKYYKVDDNGKITRLRRE 765
Query: 121 CPSDECGAGVFMASHFDRHYCGKCCLTYCFNKPE 154
CP+++CGAGVFMASHFDRHYCGKCCLTY FNKPE
Sbjct: 766 CPNEDCGAGVFMASHFDRHYCGKCCLTYVFNKPE 867
>04649
Length = 1590
Score = 159 bits (402), Expect(2) = 2e-59, Method: Compositional matrix adjust.
Identities = 77/77 (100%), Positives = 77/77 (100%)
Frame = -2
Query: 1 MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYN 60
MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYN
Sbjct: 449 MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYN 270
Query: 61 IQKESTLHLVLRLRGGA 77
IQKESTLHLVLRLRGGA
Sbjct: 269 IQKESTLHLVLRLRGGA 219
Score = 86.3 bits (212), Expect(2) = 2e-59, Method: Compositional matrix adjust.
Identities = 36/40 (90%), Positives = 40/40 (100%)
Frame = -1
Query: 109 DENGKISRLRRECPSDECGAGVFMASHFDRHYCGKCCLTY 148
DENGKI+RLRRECP+++CGAGVFMASHFDRHYCGKCCLTY
Sbjct: 123 DENGKITRLRRECPNEDCGAGVFMASHFDRHYCGKCCLTY 4
>04017
Length = 690
Score = 158 bits (400), Expect = 9e-40, Method: Compositional matrix adjust.
Identities = 77/77 (100%), Positives = 77/77 (100%)
Frame = -1
Query: 1 MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYN 60
MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYN
Sbjct: 342 MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYN 163
Query: 61 IQKESTLHLVLRLRGGA 77
IQKESTLHLVLRLRGGA
Sbjct: 162 IQKESTLHLVLRLRGGA 112
>13455
Length = 809
Score = 154 bits (388), Expect = 2e-38, Method: Compositional matrix adjust.
Identities = 76/76 (100%), Positives = 76/76 (100%)
Frame = +3
Query: 1 MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYN 60
MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYN
Sbjct: 357 MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYN 536
Query: 61 IQKESTLHLVLRLRGG 76
IQKESTLHLVLRLRGG
Sbjct: 537 IQKESTLHLVLRLRGG 584
>34270
Length = 274
Score = 120 bits (300), Expect(2) = 9e-31, Method: Compositional matrix adjust.
Identities = 59/59 (100%), Positives = 59/59 (100%)
Frame = +1
Query: 7 TLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKES 65
TLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKES
Sbjct: 52 TLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKES 228
Score = 29.3 bits (64), Expect(2) = 9e-31, Method: Compositional matrix adjust.
Identities = 13/16 (81%), Positives = 14/16 (87%)
Frame = +2
Query: 62 QKESTLHLVLRLRGGA 77
+K TLHLVLRLRGGA
Sbjct: 218 RKSPTLHLVLRLRGGA 265
>08296
Length = 897
Score = 95.1 bits (235), Expect = 9e-21, Method: Compositional matrix adjust.
Identities = 44/76 (57%), Positives = 58/76 (76%)
Frame = +1
Query: 1 MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYN 60
M I VKTLTGK I +++EP+D +E +K ++++KEGIPP QQRLIF+GKQ+ D +T DY
Sbjct: 127 MLIKVKTLTGKEIEIDIEPTDKVERIKERVEEKEGIPPQQQRLIFSGKQMNDEKTAQDYK 306
Query: 61 IQKESTLHLVLRLRGG 76
+ S LHLVL LRGG
Sbjct: 307 VIGGSVLHLVLALRGG 354
>24173
Length = 413
Score = 83.6 bits (205), Expect = 3e-17, Method: Compositional matrix adjust.
Identities = 44/72 (61%), Positives = 54/72 (75%), Gaps = 1/72 (1%)
Frame = -2
Query: 5 VKTLTGKTIT-LEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQK 63
+KTLT + + L E T+ +K +I DK+GI P+QQRL+FAGKQLEDGR LSDYNI
Sbjct: 337 LKTLTRQERSALTWEGGVTVGELKCQIYDKDGISPEQQRLVFAGKQLEDGRLLSDYNITD 158
Query: 64 ESTLHLVLRLRG 75
+STLHLV RLRG
Sbjct: 157 DSTLHLVFRLRG 122
>02863
Length = 583
Score = 52.4 bits (124), Expect(2) = 2e-16, Method: Compositional matrix adjust.
Identities = 25/46 (54%), Positives = 33/46 (71%)
Frame = +1
Query: 5 VKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQL 50
+KTLTGKT+ L E T+ +K +I DK+GI P+QQRL+FAGK
Sbjct: 325 LKTLTGKTVALTGEGGMTVGELKCQIYDKDGISPEQQRLVFAGKHW 462
Score = 48.5 bits (114), Expect(2) = 2e-16, Method: Compositional matrix adjust.
Identities = 23/28 (82%), Positives = 24/28 (85%)
Frame = +3
Query: 48 KQLEDGRTLSDYNIQKESTLHLVLRLRG 75
K LEDGR LSDYNI +STLHLVLRLRG
Sbjct: 453 KTLEDGRLLSDYNITDDSTLHLVLRLRG 536
>25295
Length = 998
Score = 49.3 bits (116), Expect = 8e-07, Method: Compositional matrix adjust.
Identities = 24/69 (34%), Positives = 42/69 (60%)
Frame = -2
Query: 8 LTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTL 67
L G+T+ + +DTI +KAK+ + G+P +Q+L + G ++D TL+ YN +T+
Sbjct: 964 LNGQTLEFSLPLTDTISVLKAKLNEVLGMPAGKQKLQYEGIFVKDSNTLAFYNFMMGATV 785
Query: 68 HLVLRLRGG 76
L ++ RGG
Sbjct: 784 QLQMKERGG 758
>14135
Length = 567
Score = 48.1 bits (113), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 24/69 (34%), Positives = 42/69 (60%)
Frame = +2
Query: 8 LTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTL 67
L G+T+ + +DTI +KAK+ + G+P +Q+L + G ++D TL+ YN +T+
Sbjct: 185 LNGQTLEFSLPLTDTISVLKAKLNEVLGMPAGKQKLQYEGIFVKDSNTLAFYNFMMGATV 364
Query: 68 HLVLRLRGG 76
L ++ RGG
Sbjct: 365 QLQMKERGG 391
>34268
Length = 463
Score = 46.2 bits (108), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 23/25 (92%), Positives = 23/25 (92%)
Frame = -2
Query: 1 MQIFVKTLTGKTITLEVEPSDTIEN 25
MQIFVKTLT KTITLEVEP DTIEN
Sbjct: 96 MQIFVKTLTCKTITLEVEPMDTIEN 22
>13753
Length = 812
Score = 42.7 bits (99), Expect = 7e-05, Method: Compositional matrix adjust.
Identities = 26/76 (34%), Positives = 44/76 (57%)
Frame = -3
Query: 1 MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYN 60
MQ+FV + T+ VE ++T+E+VKA ++++E + + + F G LED LS
Sbjct: 498 MQLFVHAQ--QIYTIGVEGAETVEDVKALVEERENVSAEDMAVYFGGSPLEDDVCLS--T 331
Query: 61 IQKESTLHLVLRLRGG 76
++ STL + R+ GG
Sbjct: 330 LEDLSTLQVEQRMLGG 283
>22667
Length = 1002
Score = 34.7 bits (78), Expect = 0.017, Method: Compositional matrix adjust.
Identities = 16/16 (100%), Positives = 16/16 (100%)
Frame = +3
Query: 61 IQKESTLHLVLRLRGG 76
IQKESTLHLVLRLRGG
Sbjct: 450 IQKESTLHLVLRLRGG 497
>25348
Length = 686
Score = 27.7 bits (60), Expect = 2.2, Method: Compositional matrix adjust.
Identities = 11/23 (47%), Positives = 15/23 (65%)
Frame = +3
Query: 54 RTLSDYNIQKESTLHLVLRLRGG 76
R L +Y ++ E L VLR+RGG
Sbjct: 456 RKLGNYYVEAEPKLAFVLRIRGG 524
>24931
Length = 786
Score = 27.3 bits (59), Expect = 3.0, Method: Compositional matrix adjust.
Identities = 11/29 (37%), Positives = 17/29 (58%)
Frame = -2
Query: 115 SRLRRECPSDECGAGVFMASHFDRHYCGK 143
+RL R CP+ ECG G+ ++ +H K
Sbjct: 335 ARLHRMCPTQECGTGLVGSAGPAQHALAK 249
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000362751 | hsapiens_gene_ensembl | RAB GTPase
activating protein 1 [Source:RefSeq_peptide;Acc:NP_036329]
(997 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
28977 241 1e-63
18450 97 2e-23
18897 71 3e-12
07199 32 1.3
26632 30 6.0
21010 29 9.6
>28977
Length = 496
Score = 241 bits (614), Expect = 1e-63, Method: Compositional matrix adjust.
Identities = 115/163 (70%), Positives = 140/163 (85%)
Frame = -2
Query: 512 NNDHLVEKYRILITKESPQDSAITRDINRTFPAHDYFKDTGGDGQDSLYKICKAYSVYDE 571
+N L+E YR LI ++SP ++ I RD+NRTFPAHD+FK++GG GQDSLY+I KAYSVYD+
Sbjct: 489 DNQQLLEDYRNLIMQDSPSEAVIQRDVNRTFPAHDFFKESGGMGQDSLYRISKAYSVYDK 310
Query: 572 EIGYCQGQSFLAAVLLLHMPEEQAFSVLVKIMFDYGLRELFKQNFEDLHCKFYQLERLMQ 631
+IGY QG SFLAA LLLHMPEEQAF VL KI+F+YG+R LFKQ FE+LH KFYQLERL+Q
Sbjct: 309 DIGYVQGLSFLAAALLLHMPEEQAFCVLKKILFEYGMRNLFKQGFEELHLKFYQLERLIQ 130
Query: 632 EYIPDLYNHFLDISLEAHMYASQWFLTLFTAKFPLYMVFHIID 674
E + DL+ HFLD+ LE HM+ASQWFLTLFTAKFPL++VFHI+D
Sbjct: 129 EQMSDLHGHFLDMGLEIHMFASQWFLTLFTAKFPLHVVFHILD 1
>18450
Length = 1440
Score = 96.7 bits (239), Expect(2) = 2e-23, Method: Compositional matrix adjust.
Identities = 56/175 (32%), Positives = 84/175 (48%), Gaps = 2/175 (1%)
Frame = +1
Query: 516 LVEKYRILITKESPQDSA--ITRDINRTFPAHDYFKDTGGDGQDSLYKICKAYSVYDEEI 573
++EKY + + Q + ITRD++R FP H+ F GG GQ L+ + KAY++++ +
Sbjct: 307 ILEKYEEYLRQTGDQKNLDEITRDLHRQFPNHEMFTSKGGYGQTDLFCVLKAYTIHNPKD 486
Query: 574 GYCQGQSFLAAVLLLHMPEEQAFSVLVKIMFDYGLRELFKQNFEDLHCKFYQLERLMQEY 633
GYCQ Q+ +AAVLL+HMP EQAF LV I Y + F E + L L++
Sbjct: 487 GYCQAQAPIAAVLLMHMPAEQAFWCLVAICEKY-VTGYFSPGLEAIQLDGEILFGLVKRT 663
Query: 634 IPDLYNHFLDISLEAHMYASQWFLTLFTAKFPLYMVFHIIDLLLCEGISVIFNVA 688
+Y H + V + D+ CEG+ V+F A
Sbjct: 664 STPIYKHLKSTTWTPSCT*PSGSCVFLPRNLSWGCVLRLWDIFFCEGVKVLFRTA 828
Score = 31.6 bits (70), Expect(2) = 2e-23, Method: Composition-based stats.
Identities = 12/41 (29%), Positives = 20/41 (48%)
Frame = +3
Query: 469 WGELLSKWHLNLNVRPKQLSSLVRNGVPEALRGEVWQLLAG 509
W ++ W ++ R K++ R G+P +R WQ L G
Sbjct: 162 WLDMFENWEKWMSKRFKKVKDRCRKGIPPGVRPRAWQYLCG 284
>18897
Length = 845
Score = 70.9 bits (172), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 50/155 (32%), Positives = 83/155 (53%), Gaps = 8/155 (5%)
Frame = +1
Query: 534 ITRDINRTFPAHDYF---KDTGGDGQDSLYKICKAYSVYDEEIGYCQGQSFLAAVLLLHM 590
I DI+RT+P + YF +D G Q L + A+++ D +GYCQG +F+A ++L+ +
Sbjct: 130 ILLDIHRTYPENIYFVHAQDPAG-LQKPLKNVLTAFALNDPHVGYCQGLNFVAGLMLIIL 306
Query: 591 -PEEQAFSVLVKIMFDYGLRELFKQNF--EDLHCKFYQ--LERLMQEYIPDLYNHFLDIS 645
EE+AF ++ D +R+L + + + L K Q L L++ +P L++H +S
Sbjct: 307 RNEEKAFWLM-----DTLIRQLLPEYYAPDMLAVKAEQELLGDLVKWKMPALFSHLDALS 471
Query: 646 LEAHMYASQWFLTLFTAKFPLYMVFHIIDLLLCEG 680
L + +WF+ LF P+ V I D L EG
Sbjct: 472 LHWSLVGMKWFICLFADVLPVETVLRIWDSLFYEG 576
>07199
Length = 1535
Score = 32.0 bits (71), Expect = 1.3, Method: Compositional matrix adjust.
Identities = 22/89 (24%), Positives = 37/89 (41%), Gaps = 1/89 (1%)
Frame = -2
Query: 516 LVEKYRILITKESPQDSAITRDINRTFPAHDYFKDTGGDGQDSLYKICKAYSVYDEEIGY 575
++ RI I + I +D+ RT +Y+K L I ++ Y+ +GY
Sbjct: 1018 FCQQKRIDINELRSYIRVIDKDVPRTDRDVEYYKGHANPHLTQLRDILATFACYNHTLGY 839
Query: 576 CQGQS-FLAAVLLLHMPEEQAFSVLVKIM 603
QG + LA L + E + F + M
Sbjct: 838 AQGMNDILARFLFVFGSEVETFWCFQRYM 752
>26632
Length = 396
Score = 29.6 bits (65), Expect = 6.0, Method: Composition-based stats.
Identities = 21/60 (35%), Positives = 31/60 (51%), Gaps = 4/60 (6%)
Frame = -1
Query: 186 RILYSFAT----AFRRSAKQTPLSATAAPQTPDSDIFTFSVSLEIKEDDGKGYFSAVPKD 241
RI+ SF A R AK+ P+ ATA+ Q S I S + ++DD K + +A +D
Sbjct: 180 RIMCSFQRSTKYAMMRRAKKMPIKATASTQNFASCIDIHSRNFWERDDDSKSHCNATWRD 1
>21010
Length = 1609
Score = 28.9 bits (63), Expect = 9.6, Method: Compositional matrix adjust.
Identities = 16/52 (30%), Positives = 29/52 (55%)
Frame = -2
Query: 593 EQAFSVLVKIMFDYGLRELFKQNFEDLHCKFYQLERLMQEYIPDLYNHFLDI 644
EQ +LV IMF Y + +F+QN+ C F Q+ + Y +++ + +D+
Sbjct: 522 EQLRDLLV*IMFHYLNKGIFRQNYR---CIFPQMHKYHHTYHNEIHTYIIDV 376
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000379243 | hsapiens_gene_ensembl |
Serine/threonine-protein kinase 6 (EC 2.7.11.1) (Aurora kinase A)
(Aurora-A) (Serine/threonine kinase 15) (Aurora/IPL1-related kinase 1)
(Aurora-related kinase 1) (hARK1) (Breast-tumor-amplified kinase).
[Source:Uniprot/SWISSPROT;Acc:O14965]
(347 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
21433 164 3e-63
03240 117 6e-27
18921 107 6e-24
01060 107 7e-24
12721 103 1e-22
14420 101 4e-22
18484 99 2e-21
00300 99 2e-21
01707 99 2e-21
14126 97 1e-20
30755 94 7e-20
06405 94 7e-20
15910 94 1e-19
09007 93 2e-19
09606 92 2e-19
13066 87 9e-18
01756 87 1e-17
04591 86 2e-17
01718 86 2e-17
17975 85 4e-17
31885 85 5e-17
11780 80 9e-17
27546 83 1e-16
21079 82 4e-16
00392 80 9e-16
01966 79 3e-15
13212 77 7e-15
13592 77 7e-15
26560 73 1e-13
29581 72 4e-13
01392 71 6e-13
19094 70 1e-12
27405 68 4e-12
19761 67 8e-12
19301 65 4e-11
14477 64 7e-11
21808 63 2e-10
00715 62 5e-10
14116 62 5e-10
26711 61 6e-10
00486 61 7e-10
28157 61 8e-10
03508 61 8e-10
07940 60 1e-09
04138 60 1e-09
12786 59 3e-09
26009 41 3e-09
04852 57 1e-08
06358 56 2e-08
28638 56 2e-08
12672 55 5e-08
18663 54 1e-07
11185 52 2e-07
25019 52 3e-07
37602 49 3e-06
07291 48 7e-06
01106 47 1e-05
18481 45 4e-05
32957 45 5e-05
07833 45 6e-05
31489 44 9e-05
17253 44 1e-04
16708 44 1e-04
20640 44 1e-04
07836 43 2e-04
17300 43 2e-04
20559 40 2e-04
38560 42 3e-04
27274 42 4e-04
20152 42 5e-04
11404 41 7e-04
29590 39 0.003
32000 39 0.004
00638 38 0.005
02638 38 0.008
31789 37 0.013
37063 35 0.038
00394 35 0.056
18401 32 0.36
36481 32 0.38
21800 32 0.39
21210 32 0.40
31120 31 0.72
17932 30 1.0
17637 27 9.5
>21433
Length = 590
Score = 164 bits (415), Expect(2) = 3e-63, Method: Compositional matrix adjust.
Identities = 79/99 (79%), Positives = 89/99 (89%)
Frame = +2
Query: 231 QRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLC 290
+RTA YI +L++AL YCH ++VIHRDIKPENLLLG G+LKIADFGWSVHAPSSRRTT+C
Sbjct: 167 KRTACYIYQLSSALEYCHYRKVIHRDIKPENLLLGLKGDLKIADFGWSVHAPSSRRTTMC 346
Query: 291 GTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPF 329
GTLDYLPPEM+EG+ HDE VDLWSLGVLCYEFLVG PP
Sbjct: 347 GTLDYLPPEMVEGKTHDENVDLWSLGVLCYEFLVGTPPL 463
Score = 95.9 bits (237), Expect(2) = 3e-63, Method: Compositional matrix adjust.
Identities = 44/64 (68%), Positives = 54/64 (84%), Gaps = 1/64 (1%)
Frame = +3
Query: 176 HQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDE-QRTA 234
HQLRRE+EIQSHLRH NILR++GYFHD TRVYLILE+AP G +Y+ELQ+ KFDE ++ A
Sbjct: 3 HQLRREIEIQSHLRHDNILRMFGYFHDKTRVYLILEFAPKGELYKELQRCHKFDENEQHA 182
Query: 235 TYIT 238
Y +
Sbjct: 183 IYTS 194
>03240
Length = 1683
Score = 117 bits (293), Expect = 6e-27, Method: Compositional matrix adjust.
Identities = 80/259 (30%), Positives = 121/259 (46%), Gaps = 49/259 (18%)
Frame = -3
Query: 133 FEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPN 192
FE + LG G FG V L R+ + + A+K L K+ + K ++ E +I + +
Sbjct: 1285 FEKIKTLGVGAFGEVSLCRKNDTGMLYAMKTLRKSDVLKRNQVAHVKAERDILAEADNEW 1106
Query: 193 ILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRV 252
+++LY F D +Y +++Y P G + L ++ DE Y+ EL A+ H
Sbjct: 1105 VVKLYYSFQDHNYLYFVMDYVPGGDLMGLLIRMEILDEPLARFYVAELVQAIESVHRMGF 926
Query: 253 IHRDIKPENLLLGSAGELKIADFG------WS----------VHA--------------- 281
IHRDIKP+N+L+ G +K+ DFG W+ HA
Sbjct: 925 IHRDIKPDNILIDRNGHIKLTDFGLCTGFRWTHNSKYYQRDGTHARQDSMEVKCQLDEQC 746
Query: 282 ------PSSRRT---------TLCGTLDYLPPEMIEGRM--HDEKVDLWSLGVLCYEFLV 324
P RR +L GT +Y+ PE++ R+ + D WS+GV+ +E LV
Sbjct: 745 QCEILKPLERRRKREQRCLAHSLVGTPNYIAPEVL-SRLGGYTSVCDWWSVGVILFEMLV 569
Query: 325 GKPPFEANTYQET-YKRIS 342
G PPF ANT ET YK I+
Sbjct: 568 GHPPFYANTPAETQYKVIN 512
>18921
Length = 697
Score = 107 bits (268), Expect = 6e-24, Method: Compositional matrix adjust.
Identities = 64/199 (32%), Positives = 109/199 (54%), Gaps = 3/199 (1%)
Frame = +2
Query: 133 FEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPN 192
F+I LG+G +G+V+ + K++ +LA+K Q+ ++ +E+ I
Sbjct: 35 FDILGKLGEGSYGSVFKSLHKETGQVLAIK-----QVPVDTDLQEIIKEISIMQQCDSKY 199
Query: 193 ILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSK-FDEQRTATYITELANALSYCHSKR 251
I++ YG + T +++++EY G+V ++ +K E+ AT + L Y HS+R
Sbjct: 200 IVKYYGSYFKNTDLWIVMEYCGAGSVSDIMRLRNKTLVEREIATILYYTLKGLXYLHSRR 379
Query: 252 VIHRDIKPENLLLGSAGELKIADFGWS--VHAPSSRRTTLCGTLDYLPPEMIEGRMHDEK 309
IHRDIK N+LL + G K+ADFG + + ++R T+ GT ++ PE+I+ +D
Sbjct: 380 KIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTPYWMAPEVIQEIGYDCV 559
Query: 310 VDLWSLGVLCYEFLVGKPP 328
D+WSLG+ E GKPP
Sbjct: 560 ADIWSLGITALEMAEGKPP 616
>01060
Length = 1800
Score = 107 bits (267), Expect = 7e-24, Method: Compositional matrix adjust.
Identities = 64/221 (28%), Positives = 114/221 (51%), Gaps = 5/221 (2%)
Frame = +1
Query: 129 ALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHL 188
AL D + +G+G +G VY R + + LA+K + + + + GV RE+ + L
Sbjct: 67 ALSDLTDFQKIGEGTYGVVYKCRHRATGRKLAMKKI-RLRGSEDGVPSSAIREIAMLREL 243
Query: 189 RHPNILRLYGYFHDATRVYLILEY--APLGTVYRELQKLSKFDEQRTATYITELANALSY 246
RH NI+ L + R++L+ E+ L + + D + +Y+ ++ + +
Sbjct: 244 RHTNIVCLEDVIMEDERLFLVFEFLSMDLKMYIDKFPEGVVLDRRLVKSYVFQIVTGIXF 423
Query: 247 CHSKRVIHRDIKPENLLLGSAGELKIADFGW--SVHAPSSRRTTLCGTLDYLPPEMIEG- 303
CH +R++HRD+KP+NLL+ G +KIADFG + P T TL Y PE++ G
Sbjct: 424 CHQRRIVHRDLKPQNLLINHTGAIKIADFGMARTFALPVRAYTHEVVTLWYRAPEILMGA 603
Query: 304 RMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRV 344
+ VD+WS+G + + L+ P F+ ++ + +I R+
Sbjct: 604 SKYSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRI 726
>12721
Length = 821
Score = 103 bits (256), Expect = 1e-22, Method: Compositional matrix adjust.
Identities = 63/214 (29%), Positives = 110/214 (51%), Gaps = 2/214 (0%)
Frame = +1
Query: 130 LEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLR 189
L+DF +G+G G V +A + + +A+K K L K L EV +
Sbjct: 94 LDDF---MKIGEGSTGIVCIATSRDGR-QMAVK---KMDLRKQQRRELLFNEVVVMRDYH 252
Query: 190 HPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHS 249
HPNI+ +Y + +++++E+ G ++ ++ DE + AT AL++ H+
Sbjct: 253 HPNIVEMYNSYLVNDELWVVMEFME-GGALTDIVTNNRMDEVQIATVCRACLKALAFLHA 429
Query: 250 KRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSS--RRTTLCGTLDYLPPEMIEGRMHD 307
VIHRDIK +++LL G++K+ DFG+ +R +L GT ++ PE+I +
Sbjct: 430 NGVIHRDIKSDSILLSHDGKVKLXDFGFCAQVTQDLQKRKSLVGTPYWMAPEVISRLPYG 609
Query: 308 EKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRI 341
+VD+WSLG++ E + +PPF + +RI
Sbjct: 610 PEVDIWSLGIMVMEMIDAEPPFFNEPPLQAMRRI 711
>14420
Length = 528
Score = 101 bits (252), Expect = 4e-22, Method: Compositional matrix adjust.
Identities = 48/151 (31%), Positives = 87/151 (57%), Gaps = 2/151 (1%)
Frame = +2
Query: 181 EVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITEL 240
E+ + ++PNI+ + +++++E+ G++ + + + DE + A E
Sbjct: 50 EILVMRENQNPNIVNYLDSYLVGEELWVVMEFLAGGSLTDVVTE-TCMDEGQIAAVCREC 226
Query: 241 ANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAP--SSRRTTLCGTLDYLPP 298
AL + H +VIHRDIK +N+LLG G +K+ DFG+ S+R+T+ GT ++ P
Sbjct: 227 LQALEFLHENQVIHRDIKSDNILLGMDGSVKLTDFGFCAQLSPEQSKRSTMVGTPYWMAP 406
Query: 299 EMIEGRMHDEKVDLWSLGVLCYEFLVGKPPF 329
E++ + + VD+WSLGV+C E + G+PP+
Sbjct: 407 EVVTRKQYGPTVDIWSLGVMCIEMIEGEPPY 499
>18484
Length = 635
Score = 99.4 bits (246), Expect = 2e-21, Method: Compositional matrix adjust.
Identities = 49/127 (38%), Positives = 75/127 (59%), Gaps = 2/127 (1%)
Frame = +1
Query: 218 VYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGW 277
+YR +Q+ KF E A Y E+A L + H + +I+RD+K +N++L S G +KIADFG
Sbjct: 7 MYR-IQQEGKFKEPVAAFYAAEIAVGLFFLHDQGIIYRDLKLDNVMLDSEGHIKIADFGM 183
Query: 278 SVHAPSSRRTT--LCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQ 335
+ TT CGT DY+ PE++ + + + VD W+ GVL +E L G+PPF+
Sbjct: 184 CKEGMTGDATTRTFCGTPDYIAPEIVLYQPYSKSVDWWAYGVLLFEMLAGQPPFDGEDED 363
Query: 336 ETYKRIS 342
E + I+
Sbjct: 364 ELFSSIT 384
>00300
Length = 2318
Score = 99.4 bits (246), Expect = 2e-21, Method: Compositional matrix adjust.
Identities = 66/214 (30%), Positives = 103/214 (48%), Gaps = 10/214 (4%)
Frame = -1
Query: 136 GRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILR 195
G +G+G+FG VY A + ++ALK + K Q ++ E++I ++H N+++
Sbjct: 1643 GNKIGEGQFGKVYTAVNMSTGELMALKEM-KFQPNDLQQLREMCDEIKIFEGIQHENLVK 1467
Query: 196 LYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHR 255
YG + + +EY GT+ E K+ E Y E+ A+++ H ++HR
Sbjct: 1466 YYGVEVHKDEMLMFMEYCDTGTI-EEAAKMG-LPEYLIRRYTREIVLAVNHLHENSIVHR 1293
Query: 256 DIKPENLLLGSAGELKIADFGWSVHAPSSRRT-----TLCGTLDYLPPEMI---EGRMHD 307
DIK N+ L S G +K+ DFG SV S L GT Y+ PE+ + +
Sbjct: 1292 DIKGANIFLTSNGHVKLGDFGCSVKLKSHTTMPGEFHNLVGTTAYMAPEVFTQNDQGGYG 1113
Query: 308 EKVDLWSLGVLCYEFLVGKPPFE--ANTYQETYK 339
D+WSLG + E GK P+ N YQ YK
Sbjct: 1112 RAADIWSLGCVVIEMATGKRPWHDLDNNYQIMYK 1011
>01707
Length = 757
Score = 99.0 bits (245), Expect = 2e-21, Method: Compositional matrix adjust.
Identities = 58/201 (28%), Positives = 108/201 (53%), Gaps = 4/201 (1%)
Frame = +1
Query: 130 LEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLR 189
+E +E +G+G +G V+ R K++ ++A+K +++ + ++ RE+ + L+
Sbjct: 61 MEKYEKIGKIGEGSYGVVFKCRNKETSQLVAIKKFVESE-DDPLIKKIAMREIRMLKQLK 237
Query: 190 HPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSK-FDEQRTATYITELANALSYCH 248
HPN++RL F R++L+ +Y T+ EL + + E I + A+++CH
Sbjct: 238 HPNLVRLIEVFRRKKRLHLVFDYVD-HTLLNELDRYPRGLPEPMVKRIIYQTLLAVNFCH 414
Query: 249 SKRVIHRDIKPENLLLGSAGELKIADFGWS--VHAPSSRRTTLCGTLDYLPPEMIEGRM- 305
IHRD+KPEN+L+ G++K+ DFG++ + P T T Y PE++ G
Sbjct: 415 QYNTIHRDVKPENILITRQGQVKLCDFGFARILTGPGDEYTDYVATRWYRAPELLVGDTQ 594
Query: 306 HDEKVDLWSLGVLCYEFLVGK 326
+ VD+W++G + E L G+
Sbjct: 595 YGPPVDVWAIGCVFAELLTGQ 657
>14126
Length = 1265
Score = 96.7 bits (239), Expect = 1e-20, Method: Compositional matrix adjust.
Identities = 69/242 (28%), Positives = 116/242 (47%), Gaps = 13/242 (5%)
Frame = +3
Query: 116 SKQKNEESKKRQWALEDFEIGRPLGKGKFGNVYLARE--KQSKFILALKVLFKAQLEKAG 173
S+ + S++R + +E +G G +G VY AR+ Q +F+ ++ E G
Sbjct: 144 SESAAKMSRRRDSTEQKYEEVAVIGNGAYGTVYKARDLRNQGEFVAMKRIRLNNTEE--G 317
Query: 174 VEHQLRREVEIQSHLR---HPNILRLYGYFHDAT-----RVYLILEYA--PLGTVYRELQ 223
+ RE+ + L HPN++RL H+ R+ L+ EY L T Y
Sbjct: 318 MPMMAIREISMLKQLEQYEHPNVVRLLDVSHNTITDREIRLNLVFEYIEHDLAT-YLAKC 494
Query: 224 KLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS-VHAP 282
R + +L N + + HS R++HRD+KP+NLL+ G LK+ADFG + +++
Sbjct: 495 PSPGLGPDRIKDLMLQLLNGVDFLHSNRIVHRDLKPQNLLISKDGRLKLADFGLARIYSF 674
Query: 283 SSRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRIS 342
TT+ TL Y PE++ + VD+WS G + E + F+ ++ + K+I
Sbjct: 675 HMALTTVVVTLWYRSPEVLMQAEYGTSVDIWSCGCIFAELFTRRALFKGSSEFDQLKKIF 854
Query: 343 RV 344
V
Sbjct: 855 EV 860
>30755
Length = 1137
Score = 94.0 bits (232), Expect = 7e-20, Method: Compositional matrix adjust.
Identities = 46/104 (44%), Positives = 64/104 (61%), Gaps = 2/104 (1%)
Frame = +2
Query: 228 FDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRT 287
F E+RT Y E+ +AL Y HS+ +I+RD+K ENLLL G +K+ADFG + RT
Sbjct: 23 FTEERTRFYGAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCKEDITYGRT 202
Query: 288 --TLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPF 329
T CGT +YL PE+++ + VD W GV+ YE + G+ PF
Sbjct: 203 TKTFCGTPEYLAPEVLDDNDYGRAVDWWGTGVVMYEMICGRLPF 334
>06405
Length = 1965
Score = 94.0 bits (232), Expect = 7e-20, Method: Compositional matrix adjust.
Identities = 63/228 (27%), Positives = 107/228 (46%), Gaps = 8/228 (3%)
Frame = +1
Query: 127 QWALEDFEIGRP--LGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEI 184
+W +E EI LG G++G+VY A K+ I+A+K L E + E I
Sbjct: 241 RWEIERTEIAMKHRLGGGQYGDVYEAMWKRYNKIVAVKTL----KEDTMALNDFLEEAAI 408
Query: 185 QSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTA-TYI-TELAN 242
++HPN+++L G Y++ E+ P G + L+ ++ + TA Y+ T++A+
Sbjct: 409 MKEMKHPNLVQLLGVCTREPPFYIVTEFMPHGNLLDYLRSSTREENGPTALMYMATQIAS 588
Query: 243 ALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGT---LDYLPPE 299
++Y +K IHRD+ N L+ + +K+ADFG + T G + + PE
Sbjct: 589 GMAYLETKNFIHRDLAARNCLVADSNMVKVADFGLARLMKDDTYTAHIGAKFPIKWTAPE 768
Query: 300 MIEGRMHDEKVDLWSLGVLCYEFLV-GKPPFEANTYQETYKRISRVRR 346
+ + D+W+ GVL +E G P+ E Y + R R
Sbjct: 769 GLAFNRFSTRSDIWAFGVLLWELATYGMSPYPGVELTEVYHLLERGYR 912
>15910
Length = 1361
Score = 93.6 bits (231), Expect = 1e-19, Method: Compositional matrix adjust.
Identities = 46/121 (38%), Positives = 74/121 (61%), Gaps = 4/121 (3%)
Frame = +2
Query: 227 KFDEQRTATYITELANALSYCHSKRVIHRDIKPENLL---LGSAGELKIADFGWS-VHAP 282
++ E+ A I+++ + + Y H+ V+HRD+KPENLL + +LK+ADFG S + P
Sbjct: 452 QYTEKDAARAISDILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLADFGLSRIIEP 631
Query: 283 SSRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRIS 342
+ +T+CGT Y PE+++G + VD+WS+GV+ Y L G PF A E Y++I
Sbjct: 632 EVQMSTVCGTPGYCAPEVLKGDKYTPSVDMWSVGVIAYILLCGYEPFFAENEFEMYRKII 811
Query: 343 R 343
+
Sbjct: 812 K 814
>09007
Length = 1440
Score = 92.8 bits (229), Expect = 2e-19, Method: Compositional matrix adjust.
Identities = 64/222 (28%), Positives = 106/222 (47%), Gaps = 15/222 (6%)
Frame = -1
Query: 135 IGRPLGKGKFGNVYLA---REKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHP 191
+ + LG+G FG V A E K +A+K L K ++ K G E +E I L H
Sbjct: 867 LSKSLGQGHFGTVRQAIWTAESGEKVQVAVKCLSKDKIHKDGQE--FLKETAIMQMLDHE 694
Query: 192 NILRLYGYFHD-ATRVYLILEYAPLGTVYRELQKLS---KFDEQRTATYITELANALSYC 247
NI+R+YG D + L+ E AP+ ++ ++++S F R + ++ + +SY
Sbjct: 693 NIVRVYGVVMDNGADIMLVTELAPMRSLLECVKEVSARVDFSVPRLCDFSQQVCDGMSYL 514
Query: 248 HSKRVIHRDIKPENLLLGSAGELKIADFGWSV-------HAPSSRRTTLCGTLDYLPPEM 300
SKR++HRD+ N+LL S ++KI+D G S + S + L + + PE
Sbjct: 513 ESKRLVHRDLAARNILLFSKSKVKISDVGVSGALGAGKEYYQSQQTIHLQNAVAWCAPES 334
Query: 301 IEGRMHDEKVDLWSLGVLCYEFLV-GKPPFEANTYQETYKRI 341
D+W+ GVL +EF G P+ Q+ + +
Sbjct: 333 FRNLCFSSASDVWAFGVLLWEFFTHGFQPWAGLNGQQIMEAV 208
>09606
Length = 1300
Score = 92.4 bits (228), Expect = 2e-19, Method: Compositional matrix adjust.
Identities = 56/236 (23%), Positives = 105/236 (44%), Gaps = 24/236 (10%)
Frame = -3
Query: 130 LEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLR 189
+E+F + LGKG+ +Y R K + +A+ + K + ++ V + +
Sbjct: 1118 MENFVLYEELGKGEHSIIYKGRRKGTINFVAIHCIEKCK------RPEVTNTVRMTHDIS 957
Query: 190 HPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHS 249
HPN+++ + ++ + ++L++E G++ L + E + L L Y HS
Sbjct: 956 HPNVVQFHEWYETSNHLWLVVELCTGGSLADILAQDHHLPETSIRDFGIHLVTGLHYIHS 777
Query: 250 KRVIHRDIKPENLLLGSAGELKIADFG----------------------WSVHAPSS--R 285
++ D++P +LL ++G LK ADFG W++ + +
Sbjct: 776 LGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQWNIQSAEEMMK 597
Query: 286 RTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRI 341
+ G+ Y+ PE+ +G DLW+LG + YE G PPF TY T ++
Sbjct: 596 QVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSGHPPFLGETYDITKDKV 429
>13066
Length = 551
Score = 87.0 bits (214), Expect = 9e-18, Method: Compositional matrix adjust.
Identities = 50/164 (30%), Positives = 87/164 (53%), Gaps = 6/164 (3%)
Frame = +3
Query: 159 LALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTV 218
LA K++ K + VE RE+++ + L HP I++++ + ++ + +A G +
Sbjct: 60 LACKIIDKEKAPVDFVEKFFPRELDLLTKLDHPYIIQIHSILQRXPKNFIFMRFAERGDL 239
Query: 219 YRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS 278
+Q++ E++ + ++ AL+Y HS V HRD+K EN+LL S +K+ADFG++
Sbjct: 240 LTYIQEVGFVKEKQAKIWFYQMTTALNYLHSYDVAHRDLKCENILLSSHFNVKLADFGFA 419
Query: 279 VHAPSSR-----RTTLCGTLDYLPPEMIEGRMHDEKV-DLWSLG 316
+ T CG+ Y PE++ G + KV D WSLG
Sbjct: 420 CACITESGEKYMSRTYCGSAAYAAPEIVYGAPYAPKVADAWSLG 551
>01756
Length = 1858
Score = 87.0 bits (214), Expect = 1e-17, Method: Compositional matrix adjust.
Identities = 66/222 (29%), Positives = 106/222 (47%), Gaps = 16/222 (7%)
Frame = -3
Query: 139 LGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYG 198
+G+G FG V+ AR K++K ++A+K + EK G RE++I L H N++ L
Sbjct: 1718 IGQGTFGEVFKARCKKTKQVVAMKKVLMDN-EKEGFPITALREIKILQLLNHENVVDLIE 1542
Query: 199 YFH----DATR----VYLILEYA--PLGTVYRELQKLSKFDEQRTATYITELANALSYCH 248
A R YL+ E+ L + + + E + + +L N L Y H
Sbjct: 1541 ICSTKATSANRYKSMFYLVFEFCEHDLAGLLSNMSVVFNLPEIKEV--MKQLMNGLYYIH 1368
Query: 249 SKRVIHRDIKPENLLLGSAGELKIADFG----WSVHAPS-SRRTTLCGTLDYLPPEMIEG 303
+++HRD+K N+L+ G LK+ADFG +SV+ +R T TL Y PPE++ G
Sbjct: 1367 RNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRPPELLLG 1188
Query: 304 -RMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRV 344
R + +D W G + E P + T Q I+++
Sbjct: 1187 DRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQNQLTLITQL 1062
>04591
Length = 1117
Score = 86.3 bits (212), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 60/184 (32%), Positives = 88/184 (47%), Gaps = 12/184 (6%)
Frame = -2
Query: 171 KAGVEHQLRREVEIQSHLRHPNILRLYGYFHD--------ATRVYLILEYAP--LGTVYR 220
K G RE++I L H N+++L H + YLI EY L +
Sbjct: 1101 KEGFPITALREIKILQQLEHENVVQLQEICHTQAGPYNRYKSTFYLIFEYCDYDLAGLLN 922
Query: 221 ELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS-V 279
L+ KF +++L N L Y H+K+++HRDIK N+LL G LK+ADFG S
Sbjct: 921 NLR--VKFSLADKKNLMSQLLNGLFYIHTKQILHRDIKAANILLTRDGVLKLADFGLSRP 748
Query: 280 HAPSSRRTTLCGTLDYLPPEMIEG-RMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETY 338
S R T TL Y PPE++ G R + ++D+W +G + E KP + + Q
Sbjct: 747 WVKSKRLTNRVVTLWYRPPELLLGEREYGPEIDMWGVGCIMAEMWSRKPLMQGRSEQHQL 568
Query: 339 KRIS 342
I+
Sbjct: 567 SLIT 556
>01718
Length = 959
Score = 85.9 bits (211), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 62/209 (29%), Positives = 99/209 (47%), Gaps = 11/209 (5%)
Frame = +3
Query: 130 LEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLR 189
L+DF I +G G F V+ + + ++ALK+ H + REV++ + L+
Sbjct: 147 LDDF-ICEKIGAGFFSEVFKVTHRITGQVMALKMN-----TMTSNRHNMLREVQLLNRLQ 308
Query: 190 HPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTAT----YITELANALS 245
H NILR G +++ + EY P G + Q L K DE+ T LA L
Sbjct: 309 HANILRFMGVCVHEGQLHALTEYIPSGNLE---QLLEKKDEELPWTQRIQLTLGLARGLD 479
Query: 246 YCHSKRVIHRDIKPENLLL----GSAGELKIADFGWSVHAP---SSRRTTLCGTLDYLPP 298
Y HS R IHRD+ +N+L+ IADFG + P + G+ ++ P
Sbjct: 480 YLHSTRFIHRDLTSKNILIRREDNHGYHAVIADFGLATKIPDPLDKEKLPTVGSPYWMAP 659
Query: 299 EMIEGRMHDEKVDLWSLGVLCYEFLVGKP 327
E++ G ++E+ DL+S+G++ E P
Sbjct: 660 EVLNGHFYNERADLFSVGIIMCEITARIP 746
>17975
Length = 449
Score = 85.1 bits (209), Expect = 4e-17, Method: Compositional matrix adjust.
Identities = 51/137 (37%), Positives = 80/137 (58%), Gaps = 2/137 (1%)
Frame = +3
Query: 144 FGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDA 203
F V LAR + +A+KV+ K +L++ H L +EV ++HPN++RLY
Sbjct: 6 FAVVKLARHVFTGEKVAVKVIDKTKLDEVSRSH-LFQEVRCMKLVQHPNVVRLYEVIDTQ 182
Query: 204 TRVYLILEYAPLGTVYRELQKLSKFDEQRTAT-YITELANALSYCHSKRVIHRDIKPENL 262
T++YLILE G +Y + + S E++ A Y ++ A+SYCH V+HRD+KPEN+
Sbjct: 183 TKLYLILELGDGGDMYDYIMRHSGGLEEKLAKRYFRQIVEAISYCHKLHVVHRDLKPENV 362
Query: 263 LLGSA-GELKIADFGWS 278
+ G +K+ DFG+S
Sbjct: 363 VFFEKPGLVKLTDFGFS 413
>31885
Length = 529
Score = 84.7 bits (208), Expect = 5e-17, Method: Compositional matrix adjust.
Identities = 48/158 (30%), Positives = 81/158 (51%), Gaps = 6/158 (3%)
Frame = -2
Query: 182 VEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELA 241
V++ + L HP ++ L+ F D ++++++ G + +Q+ F E Y+ +LA
Sbjct: 519 VDMLTRLDHPFLVNLWYAFQDEEDLFMVVDLFLGGDLRYHMQQEVSFREDCVKFYLCQLA 340
Query: 242 NALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSR-RTTLCGTLDYLPPEM 300
L Y S++++HRDIKP+N+LL G + DF + T+ GT Y+ PE+
Sbjct: 339 LVLDYLRSQKIVHRDIKPDNILLDEQGHCHVTDFNIATQLEDDELATSTSGTRPYMAPEV 160
Query: 301 I-----EGRMHDEKVDLWSLGVLCYEFLVGKPPFEANT 333
E R + VD WSLGV +E L + PF ++
Sbjct: 159 YGVAINERRGYGFPVDWWSLGVSLFELLKKRRPFSVHS 46
>11780
Length = 1713
Score = 80.5 bits (197), Expect(2) = 9e-17, Method: Compositional matrix adjust.
Identities = 57/202 (28%), Positives = 100/202 (49%), Gaps = 7/202 (3%)
Frame = +3
Query: 121 EESKKRQW--ALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQL 178
+E K W A +D EIG +GKG FG+VY + V K +K E
Sbjct: 561 QEFKSGGWVIAXQDLEIGEAIGKGDFGDVYKGMYRGQP------VAIKQLKDKDRGEQSF 722
Query: 179 RREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSK--FDEQRTATY 236
+E + + LRH N++RL G T ++L+ E+ G + L+ + ++ +
Sbjct: 723 LQEASVMTSLRHDNLVRLIGVVLGET-IFLVTEFMGKGNLVEYLRSRGRSVITKKDQINF 899
Query: 237 ITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYL 296
T+ A+ Y SKR++HRD+ N+L+ G+ K++DFG + S +T++ + +
Sbjct: 900 ATDTCAAMEYLESKRLVHRDLAARNVLVHDDGKAKVSDFGLAKFGDFS-QTSVKFPIKWT 1076
Query: 297 PPEMI-EGRMHDE--KVDLWSL 315
PE + E ++H + V+LW +
Sbjct: 1077APEALRENKIH*QVRHVELWHI 1142
Score = 23.5 bits (49), Expect(2) = 9e-17, Method: Compositional matrix adjust.
Identities = 9/22 (40%), Positives = 15/22 (68%), Gaps = 1/22 (4%)
Frame = +1
Query: 309 KVDLWSLGVLCYE-FLVGKPPF 329
K D+WS G+L +E + G+ P+
Sbjct: 1114 KSDMWSFGILLWEIYSFGRVPY 1179
>27546
Length = 426
Score = 83.2 bits (204), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 42/120 (35%), Positives = 70/120 (58%)
Frame = -1
Query: 159 LALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTV 218
LA K++ KA+ V+ RE+EI + L HPNI++++ ++++ + YA G +
Sbjct: 396 LACKIIDKAKAPIDFVKKFFPRELEILTRLDHPNIIQIHSILQRGPKIFIFMRYAEKGDM 217
Query: 219 YRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS 278
++K DE +T + ++A AL Y HS + HRD+K EN+LL +KIADFG++
Sbjct: 216 LSHIKKTGPIDEAQTKVWFFQMAKALQYLHSHDIAHRDLKCENILLSKRLNVKIADFGFA 37
>21079
Length = 878
Score = 81.6 bits (200), Expect = 4e-16, Method: Compositional matrix adjust.
Identities = 42/148 (28%), Positives = 79/148 (53%), Gaps = 4/148 (2%)
Frame = +1
Query: 190 HPNILRLYGYFHDATRVYLILEYAPLGTVY-RELQKLSKFDEQRTATYITELANALSYCH 248
HP +L L+ F + L++E+ G ++ R ++ E+ ++ ++ + + Y H
Sbjct: 1 HPKLLMLWDAFEAPRTMVLVMEFVGAGELFERVIRDDFVLTERDCVHFVRQICSGVGYMH 180
Query: 249 SKRVIHRDIKPENLLLGS--AGELKIADFGWS-VHAPSSRRTTLCGTLDYLPPEMIEGRM 305
++ ++H D+KPEN+L S + ++KI DFG + + P L GT +++ PE++
Sbjct: 181 TQSILHLDLKPENVLCVSDNSNQIKIIDFGLARFYKPGDSLQVLFGTPEFIAPEVVNYDE 360
Query: 306 HDEKVDLWSLGVLCYEFLVGKPPFEANT 333
+ D+WS+GV+CY L G P T
Sbjct: 361 INFTTDMWSIGVICYILLSGLSPSRVTT 444
>00392
Length = 668
Score = 80.5 bits (197), Expect = 9e-16, Method: Compositional matrix adjust.
Identities = 48/175 (27%), Positives = 91/175 (52%), Gaps = 9/175 (5%)
Frame = +3
Query: 177 QLRREVEIQSHLRHPNILRLYGYFHDATR-----VYLILEYAPLGTVYRELQKLSKFDEQ 231
+ + E E+ L+HPNI+R + Y+ + + L+ E GT+ L++ K + +
Sbjct: 69 RFKEEAEMLKELQHPNIVRFFDYWEEHNHRNRKVIILVTELMTSGTLKTYLKRFKKPNVK 248
Query: 232 RTATYITELANALSYCHSKR--VIHRDIKPENLLL-GSAGELKIADFGWSVHAPSSRRTT 288
+ ++ L + H++ VIHRD+K +N+ + G G +KI D G + S +
Sbjct: 249 ILKNWCRQVLKGLYFLHTRTPPVIHRDLKCDNIFITGPTGSVKIGDLGLATLKNQSFAKS 428
Query: 289 LCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPF-EANTYQETYKRIS 342
+ GT +++ PEM E +DE VD+++ G+ E + P+ E + + YKR++
Sbjct: 429 VIGTPEFMAPEMYEEH-YDEAVDVYAFGMCMLEMASSEYPYSECSNAAQIYKRVT 590
>01966
Length = 1735
Score = 78.6 bits (192), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 42/135 (31%), Positives = 70/135 (51%), Gaps = 4/135 (2%)
Frame = -1
Query: 173 GVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEY--APLGTVYRELQKLSKFDE 230
GV RE+ + LRH NI+ L + R++L+ E+ L + + D
Sbjct: 1588 GVPSSAIREIAMLRELRHTNIVCLEDVIMEDERLFLVFEFLSMDLKMYIDKFPEGVVLDR 1409
Query: 231 QRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGW--SVHAPSSRRTT 288
+ +Y+ ++ +++CH +R++HRD+KP+NLL+ G +KIADFG + P T
Sbjct: 1408 RLVKSYVFQIVTGINFCHQRRIVHRDLKPQNLLINHTGAIKIADFGMARTFALPVRAYTH 1229
Query: 289 LCGTLDYLPPEMIEG 303
TL Y PE++ G
Sbjct: 1228 EVVTLWYRAPEILMG 1184
>13212
Length = 1067
Score = 77.4 bits (189), Expect = 7e-15, Method: Compositional matrix adjust.
Identities = 46/130 (35%), Positives = 69/130 (53%), Gaps = 7/130 (5%)
Frame = -1
Query: 206 VYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLG 265
V+ +L + L ++ +L+K E + E+ AL + H VIHRDIK N+LL
Sbjct: 1049 VFRVLWWGALDSIMVDLEK--PMTEAQICYVCHEMCMALDFLHRHHVIHRDIKAGNVLLT 876
Query: 266 SAGELKIADFGWSVHAPSS--RRTTLCGTLDYLPPEMI-----EGRMHDEKVDLWSLGVL 318
GE+K+ADFG S + +R T GT ++ PE++ + +D K D+WSLGV
Sbjct: 875 IDGEVKLADFGVSAKNTQTQQKRDTFIGTPYWMAPEVVLCETLKDTPYDFKADIWSLGVT 696
Query: 319 CYEFLVGKPP 328
EF +PP
Sbjct: 695 LIEFAQIEPP 666
>13592
Length = 980
Score = 77.4 bits (189), Expect = 7e-15, Method: Compositional matrix adjust.
Identities = 56/215 (26%), Positives = 104/215 (48%), Gaps = 14/215 (6%)
Frame = +2
Query: 139 LGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYG 198
+G+G+FG VY A + ++A+K + E +++ + E++I ++H N++R YG
Sbjct: 8 IGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETRALKN-VAEELKILEGIKHKNLVRYYG 184
Query: 199 YFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIK 258
+ + +E GT+ ++ E + + +L + ++ H ++HRDIK
Sbjct: 185 IEVHREELLIFMELCSEGTLESLVELTGGLPEALSRRFTAQLLSGVAELHKHGIVHRDIK 364
Query: 259 PENL-LLGSAGELKIADFGWSVHAPSSRRTTL-------CGTLDYLPPEMI---EGRMHD 307
N+ L+ + LK+ DFG +V + TT+ GT Y+ PE+ H
Sbjct: 365 TANIFLVDGSNSLKLGDFGSAVKIQA--HTTVPGELQGYVGTQAYMAPEVFTKTNSDGHG 538
Query: 308 EKVDLWSLGVLCYEFLVGKPP---FEANTYQETYK 339
D+WS+G + E GK P F++N +Q +K
Sbjct: 539 RLADIWSVGCVVVEMASGKRPWAQFDSN-FQIMFK 640
>26560
Length = 398
Score = 73.2 bits (178), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 39/128 (30%), Positives = 66/128 (51%), Gaps = 1/128 (0%)
Frame = -1
Query: 218 VYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGW 277
++ L + F E+ Y E+ L + HS+ V++RD+KP N+LL G ++I+D G
Sbjct: 395 LHYHLSQHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGL 216
Query: 278 SVHAPSSRRTTLCGTLDYLPPE-MIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQE 336
+ R GT Y+ PE +++G+ +D D +S G + Y+ L G PF + +
Sbjct: 215 ACDFSKKRPHASVGTHGYMAPEVLMKGQSYDSSADWFSFGCMLYKLLKGHSPFRQHNQGQ 36
Query: 337 TYKRISRV 344
RI R+
Sbjct: 35 A--RIDRM 18
>29581
Length = 1278
Score = 71.6 bits (174), Expect = 4e-13, Method: Compositional matrix adjust.
Identities = 49/148 (33%), Positives = 73/148 (49%), Gaps = 7/148 (4%)
Frame = -2
Query: 187 HLRHPNILRL----YGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELAN 242
+LRH NI++L G D+ ++L++EY + F E + + +L
Sbjct: 1187 NLRHQNIVQLQEVVVGKSLDS--LFLVMEYCEQDLASLLDNMPAPFSESQVKCIVLQLLK 1014
Query: 243 ALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVH--APSSRRTTLCGTLDYLPPEM 300
L Y H +IHRD+K NLL+ G +KIADFG + + P T TL Y PE+
Sbjct: 1013 GLRYLHEAFIIHRDLKVSNLLMTDKGCVKIADFGLARNYGKPQKPMTPKVVTLWYRAPEL 834
Query: 301 IEG-RMHDEKVDLWSLGVLCYEFLVGKP 327
+ G + H +D+WS G + E L KP
Sbjct: 833 LFGSKTHSTAIDMWSAGCILGELLGHKP 750
>01392
Length = 1806
Score = 71.2 bits (173), Expect = 6e-13, Method: Compositional matrix adjust.
Identities = 40/115 (34%), Positives = 63/115 (54%), Gaps = 15/115 (13%)
Frame = -1
Query: 230 EQRTATYITELANALSYCHSKRVIHRDIKPENLL---LGSAGELKIADF----GWSVHAP 282
E+ + + +A AL + HSK + HRD+KPEN+L L +KI DF G S
Sbjct: 1794 EREASLVVRHIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGISCDGD 1615
Query: 283 SSRRTTL---CGTLDYLPPEMIEGRM-----HDEKVDLWSLGVLCYEFLVGKPPF 329
++ L G+ +Y+ PE+++ + +D++ DLWSLG++ Y L G PPF
Sbjct: 1614 GTKTPELLTPVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILYIMLCGYPPF 1450
>19094
Length = 898
Score = 70.1 bits (170), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 39/105 (37%), Positives = 58/105 (55%), Gaps = 2/105 (1%)
Frame = +1
Query: 230 EQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS--VHAPSSRRT 287
E+ AT + L Y HS+R IHRDIK N+LL + G K+ADFG + + ++R
Sbjct: 55 EREIATILYYTLKGL*YLHSRRKIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRN 234
Query: 288 TLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEAN 332
T+ GT ++ PE+I+ +D D+WSLG+ E G E +
Sbjct: 235 TVIGTPYWMAPEVIQEIGYDCVADIWSLGITALEMAEGNLHMETS 369
>27405
Length = 532
Score = 68.2 bits (165), Expect = 4e-12, Method: Compositional matrix adjust.
Identities = 47/175 (26%), Positives = 84/175 (48%), Gaps = 5/175 (2%)
Frame = -3
Query: 144 FGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLR----HPNILRLYGY 199
FG VY R+ + + A+K L K +++ G E E + S + P I+ +
Sbjct: 527 FGEVYGCRKADTGKMYAMKCLDKKRIKMKGGETLALNERIMLSLVSTGEGSPFIVCMTYA 348
Query: 200 FHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKP 259
F ++ IL+ G ++ L + F E+ Y E+ L + HS+ V++RD+KP
Sbjct: 347 FQTPEKLCFILDLMNGGDLHYHLSQHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKP 168
Query: 260 ENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPE-MIEGRMHDEKVDLW 313
N+LL G ++I+D G + + GT Y+ PE +++G+ +D D +
Sbjct: 167 ANILLDENGHVRISDLGLACDFSKKKPHASVGTHGYMAPEVLMKGQAYDSSADWF 3
>19761
Length = 473
Score = 67.4 bits (163), Expect = 8e-12, Method: Compositional matrix adjust.
Identities = 30/97 (30%), Positives = 60/97 (61%), Gaps = 4/97 (4%)
Frame = -3
Query: 230 EQRTATYITELANALSYCHSKR--VIHRDIKPENLLLGSAGELKIADFGWS--VHAPSSR 285
E+ ++ + A+AL+Y H+ ++HRD+KP+N+ + G++++ D G + + P+
Sbjct: 426 ERLIVCWLMQTASALNYMHTHTPVILHRDLKPQNIYVTEKGDVRLGDLGLARKLTGPADF 247
Query: 286 RTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEF 322
T+ GT+ YL PE++ + ++ K D+WSLG + Y+
Sbjct: 246 ATSQVGTIMYLSPEILSQQPYNSKSDIWSLGCVFYDI 136
>19301
Length = 712
Score = 65.1 bits (157), Expect = 4e-11, Method: Compositional matrix adjust.
Identities = 33/101 (32%), Positives = 56/101 (55%), Gaps = 2/101 (1%)
Frame = +2
Query: 180 REVEIQS--HLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYI 237
+E +I++ L HPNI+ G A +I+EY P G +Y L+ + +
Sbjct: 410 KETDIRNLRKLNHPNIISFKGVCTQAPCYCIIMEYCPYGQLYEVLRDGKEIPPALVLDWS 589
Query: 238 TELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS 278
++A+ ++Y HS ++IHRD+K N+L+ +KI+DFG S
Sbjct: 590 KQIASGMNYLHSHKIIHRDLKSPNVLVAKNDVVKISDFGTS 712
>14477
Length = 493
Score = 64.3 bits (155), Expect = 7e-11, Method: Compositional matrix adjust.
Identities = 44/142 (30%), Positives = 73/142 (51%), Gaps = 2/142 (1%)
Frame = -1
Query: 139 LGKGKFGNVY--LAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRL 196
LG G FG+V + R + +A+KVL A L+ + V+ +L +E E+ + H +I+RL
Sbjct: 466 LGAGNFGSVMKGVCRLDDREIPVAIKVLKNADLDPS-VQSELIKEAEVMKKMDHMHIVRL 290
Query: 197 YGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRD 256
G T + L+LE A LG + + L K + +++ + Y + + +HRD
Sbjct: 289 IGLCEGET-MMLVLELAKLGPLNKFLPKNKHLPLWNILELMWQVSQGMEYLEANKFVHRD 113
Query: 257 IKPENLLLGSAGELKIADFGWS 278
+ N+LL KI+DFG S
Sbjct: 112 LAARNILLCDEHFAKISDFGMS 47
>21808
Length = 1011
Score = 63.2 bits (152), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 44/171 (25%), Positives = 74/171 (43%), Gaps = 5/171 (2%)
Frame = +1
Query: 181 EVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYI-TE 239
E +I LRHP +++LY +++I E G++ LQ + + I +
Sbjct: 82 EAQIMKKLRHPKLIQLYAVCTQDDPIFIITELMKNGSLLEFLQGKGRVLKLPALIDIGAQ 261
Query: 240 LANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGT---LDYL 296
+A ++Y S+ IHRD+ N+L+ +KIADFG + G + +
Sbjct: 262 IACGMAYLESQNYIHRDLAARNILVSDNNTVKIADFGLARVIKEDEYEARVGARFPIKWT 441
Query: 297 PPEMIEGRMHDEKVDLWSLGVLCYEFLV-GKPPFEANTYQETYKRISRVRR 346
PE K D+WS G+L E + G+ P+ T E ++ R
Sbjct: 442 APEAANYNRFTIKSDVWSFGILLTETVTYGRVPYPGMTNAEVLHQVEHGYR 594
>00715
Length = 1788
Score = 61.6 bits (148), Expect = 5e-10, Method: Compositional matrix adjust.
Identities = 48/177 (27%), Positives = 77/177 (43%), Gaps = 33/177 (18%)
Frame = +1
Query: 188 LRHPNILRLYGY-----FHDATRVYLILEY-APLG--TVYRELQKLSKFDEQRTATYITE 239
LRH N++ + G F D +L +EY PL T+ + Q+ D + +
Sbjct: 97 LRHVNVVSILGATSLHRFEDGA--WLAMEYVGPLNLQTILNDHQQ--DIDSSMRLSLALQ 264
Query: 240 LANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVH------------------- 280
+A L Y HS ++H D+KP N LL +L+IADFG H
Sbjct: 265 MARGLHYLHSINIVHLDLKPANCLLTRDLKLRIADFG-CCHQLTPTGLDMGEREGGMAGN 441
Query: 281 ------APSSRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEA 331
+ + L GTL Y PE+++G + D++SLG+ ++ + P+E
Sbjct: 442 ELELTPVQGAWKNELAGTLAYRAPELLKGLQPSVRSDVYSLGITLWQMCTRQGPYEG 612
>14116
Length = 1017
Score = 61.6 bits (148), Expect = 5e-10, Method: Compositional matrix adjust.
Identities = 56/217 (25%), Positives = 96/217 (44%), Gaps = 24/217 (11%)
Frame = -1
Query: 131 EDFEIGRPLGKGKFGNV---YLAR-EKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQS 186
E +G +GKG FG V +L E++ ++A+K L RE+E+QS
Sbjct: 636 EFLTMGEEIGKGNFGCVKRGFLTLPEQKGDILVAVKTLHNNN----------PREIELQS 487
Query: 187 HLR---------HPNILRLYGY---FHDATRVYL-ILEYAPLGTVYRELQKLSKFDEQRT 233
L+ H N+L L G D V L +++ L T R+ Q +
Sbjct: 486 FLQEALIMKDFHHSNVLTLIGICLNLDDMPLVVLPFMKHGDLLTYIRDDQHQPTI--KDL 313
Query: 234 ATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS-------VHAPSSRR 286
Y ++A + Y + +HRD+ N +L +K+ADFG + ++ +++
Sbjct: 312 IMYGVDIARGMDYLAGLKFVHRDLAARNCMLDEDFHVKVADFGLARDIYEKEYYSSENKK 133
Query: 287 TTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFL 323
L + ++ E +E +D K D+WS GV+ +E L
Sbjct: 132 AKL--PVKWMALESLEKGNYDSKTDVWSYGVVLWELL 28
>26711
Length = 405
Score = 61.2 bits (147), Expect = 6e-10, Method: Compositional matrix adjust.
Identities = 33/107 (30%), Positives = 59/107 (55%), Gaps = 3/107 (2%)
Frame = -2
Query: 237 ITELANALSYCHSKRVIHRDIKPENLLLGS--AGELKIADFGWSVHAPSSRRTTLC-GTL 293
+ ++ + L + H++ V+H D+KP NLLL +++ DFG + + T L GT
Sbjct: 398 VKQVLDILQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARKLYPPQETFLNHGTP 219
Query: 294 DYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKR 340
+ PE ++ + D+W +GVL Y L G+ PF+A++ E+ K+
Sbjct: 218 GFTSPEALDVKPISTASDVWGVGVLAYILLSGQSPFQADSATESLKK 78
>00486
Length = 797
Score = 60.8 bits (146), Expect = 7e-10, Method: Compositional matrix adjust.
Identities = 25/60 (41%), Positives = 37/60 (61%)
Frame = -2
Query: 288 TLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVRRN 347
T CGT++Y+ PE++ H + VD WSLG L Y+ L G PPF A ++T +I + + N
Sbjct: 781 TFCGTIEYMAPEILTRTGHGKAVDWWSLGALMYDMLTGSPPFTAENRKKTIDKILKGKLN 602
>28157
Length = 400
Score = 60.8 bits (146), Expect = 8e-10, Method: Compositional matrix adjust.
Identities = 39/106 (36%), Positives = 57/106 (53%), Gaps = 7/106 (6%)
Frame = +3
Query: 178 LRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLS---KFDEQRTA 234
+E++ S + HPNI+ LYG D V L++EYA G++Y L ++
Sbjct: 51 FMQELKQLSRVSHPNIVCLYGACRDHP-VCLVMEYAEGGSLYNVLHGSGPQPQYTAAHAM 227
Query: 235 TYITELANALSYCHS---KRVIHRDIKPENLLLGSAG-ELKIADFG 276
++ + A + Y H K +IHRD+KP NLLL G +LKI DFG
Sbjct: 228 NWLLQCALGVEYLHGMKPKALIHRDLKPPNLLLIQCGTKLKICDFG 365
>03508
Length = 1463
Score = 60.8 bits (146), Expect = 8e-10, Method: Compositional matrix adjust.
Identities = 31/109 (28%), Positives = 57/109 (52%), Gaps = 3/109 (2%)
Frame = +1
Query: 223 QKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAG-ELKIADFGWS-VH 280
Q F + Y+ EL AL +CHS ++HRD+KP N+++ +L++ D+G + +
Sbjct: 847 QLYQTFTDYDIRFYLYELMKALDFCHSMGIMHRDVKPHNVMIDHENKKLRLIDWGLAEFY 1026
Query: 281 APSSRRTTLCGTLDYLPPE-MIEGRMHDEKVDLWSLGVLCYEFLVGKPP 328
P + + PE +++ +M+D +D+WSLG + + K P
Sbjct: 1027HPGMEYNVRVASRYFKGPELLLDYQMYDYSLDMWSLGCMFASMIFRKEP 1173
>07940
Length = 1336
Score = 60.5 bits (145), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 36/100 (36%), Positives = 54/100 (54%), Gaps = 5/100 (5%)
Frame = -3
Query: 235 TYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS--VHAPSSRRTTLCGT 292
+Y ++A + Y SK+ IHRD+ N+L+ LKIADFG + + R T G
Sbjct: 335 SYAYQVARGMEYLASKQCIHRDLAARNVLVAEEYVLKIADFGLTRNLQQFDYYRKTTDGR 156
Query: 293 L--DYLPPEMIEGRMHDEKVDLWSLGVLCYE-FLVGKPPF 329
L ++ PE + R + K D+WS GVL +E F +G P+
Sbjct: 155 LPVKWMAPEALFDRKYTSKSDVWSYGVLLWEIFTLGGNPY 36
Score = 33.9 bits (76), Expect = 0.090, Method: Compositional matrix adjust.
Identities = 28/95 (29%), Positives = 49/95 (51%), Gaps = 7/95 (7%)
Frame = -3
Query: 131 EDFEIGRPLGKGKFGNVYLAREKQSKF------ILALKVLFKAQLEKAGVEHQLRREVEI 184
E +G LG+G FG V + E F +A+K+L + ++ ++ L RE+E+
Sbjct: 842 ERLVLGDRLGEGAFGLV-MKGEAMGIFKDNNSVTVAVKMLKEDATDREMMD--LIREMEM 672
Query: 185 QSHL-RHPNILRLYGYFHDATRVYLILEYAPLGTV 218
+ +H NI+ L G +Y+I+E+AP G +
Sbjct: 671 MKVIGKHKNIINLLGCCTQRGALYVIVEFAPHGNL 567
>04138
Length = 800
Score = 60.5 bits (145), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 36/107 (33%), Positives = 55/107 (51%), Gaps = 6/107 (5%)
Frame = +1
Query: 244 LSYCHSKRVIHRDIKPENLLLGSAGELKIADFG----WSVHAPS-SRRTTLCGTLDYLPP 298
L Y H +++HRD+K N+L+ G LK+ADFG +SV+ +R T TL Y PP
Sbjct: 52 LYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRPP 231
Query: 299 EMIEG-RMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRV 344
E++ G R + +D W G + E P + T Q I+++
Sbjct: 232 ELLLGDRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQNQLTLITQL 372
>12786
Length = 460
Score = 58.9 bits (141), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 37/127 (29%), Positives = 54/127 (42%), Gaps = 24/127 (18%)
Frame = -3
Query: 228 FDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRT 287
D Y E+ A+ H++ VIH D+KP N +L AG LK+ DFG + + +
Sbjct: 419 LDRMMIKFYWREMLRAVKALHNEGVIHSDLKPANFML-VAGNLKLIDFGIANTLQQDKTS 243
Query: 288 TL----CGTLDYLPPEMIEGRMHDE--------------------KVDLWSLGVLCYEFL 323
L GT Y+ PE I D + D+WSLG + Y +
Sbjct: 242 VLKDSRVGTPSYMSPEAIMAACDDSADDSMEEDGHRTKPKYKVGVRSDVWSLGCILYNMV 63
Query: 324 VGKPPFE 330
G+ PF+
Sbjct: 62 YGRTPFQ 42
>26009
Length = 886
Score = 40.8 bits (94), Expect(2) = 3e-09, Method: Compositional matrix adjust.
Identities = 17/49 (34%), Positives = 30/49 (61%)
Frame = +3
Query: 216 GTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLL 264
GT ++ + + + +L +AL + HSK+++HRDIKPEN+L+
Sbjct: 666 GTCLTPSRRNKACGSREAKSVMKQLVSALDFMHSKQLVHRDIKPENVLI 812
Score = 37.7 bits (86), Expect(2) = 3e-09, Method: Compositional matrix adjust.
Identities = 26/91 (28%), Positives = 47/91 (51%), Gaps = 2/91 (2%)
Frame = +2
Query: 131 EDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLR- 189
E +++ + LG+G +G V LAR + + +ALK+L K+ + + +RE ++ L
Sbjct: 416 EHYDVCKELGRGTYGKVVLARCRHTGTQVALKLLPKSCTKL----REFQREFQLSYFLSP 583
Query: 190 HPNILRLYGY-FHDATRVYLILEYAPLGTVY 219
H NI+ Y F + E+A LG ++
Sbjct: 584 HANIIDTYNVAFQTRSSYVFAQEHAVLGDLF 676
>04852
Length = 1462
Score = 57.0 bits (136), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 33/110 (30%), Positives = 59/110 (53%), Gaps = 3/110 (2%)
Frame = +1
Query: 235 TYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTL- 293
+Y ++A + + S++ IHRD+ N+L+ LKIADFG S ++ + G L
Sbjct: 337 SYAFQIARGMEFLASRKCIHRDLAARNVLVTEEHVLKIADFGLSRTGDYYKKRS-GGRLP 513
Query: 294 -DYLPPEMIEGRMHDEKVDLWSLGVLCYE-FLVGKPPFEANTYQETYKRI 341
++ PE + + K D+WS GV+ +E F +G P+ + +E Y ++
Sbjct: 514 VKWMAPEALFDMRYTTKSDVWSFGVVLWEIFSLGGMPYASIPNEELYSKL 663
>06358
Length = 1517
Score = 56.2 bits (134), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 57/236 (24%), Positives = 106/236 (44%), Gaps = 36/236 (15%)
Frame = +3
Query: 140 GKGKFGNVYLAREKQSK-----FILALKVLFK-AQLEKAGVEHQLRREVEIQSHLRHPNI 193
G G V+ A +K +K F+ K + + ++ ++ + LR V+ + LRHP I
Sbjct: 33 GPGLLWKVFAASKKSTKEEASVFVFEKKSVDRYSRRDREAIVEVLRVGVQQLTKLRHPKI 212
Query: 194 LRLYGYFHD-------------ATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITEL 240
L + + A+ ++ + + + TV +ELQ +D + + ++
Sbjct: 213 LAVINPLEESRETLAFATEPVFASLANVLGDLSSIXTVPKELQDYQLYDVE-IKHGLLQV 389
Query: 241 ANALSYCHSK-RVIHRDIKPENLLLGSAGELKIADFGWSVHA--PSSR---------RTT 288
AL + H+ +++HR++ PE ++L G K+A + + V + P S R+
Sbjct: 390 TEALGFLHNDAKMMHRNVCPEAIMLTKLGSWKLAGYEFCVRSSDPQSTDPSYPFYEWRSD 569
Query: 289 LCGT----LDYLPPEMIEGRMHDEKVDLWSLGVLCYE-FLVGKPPFEANTYQETYK 339
+ LD++ PE + D++SLG+L Y F GKP FE N +K
Sbjct: 570 IAPVTQPHLDFMAPEYVLTMQCGTGSDMFSLGLLVYSVFAKGKPLFECNGELSAFK 737
>28638
Length = 1458
Score = 56.2 bits (134), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 41/132 (31%), Positives = 60/132 (45%), Gaps = 5/132 (3%)
Frame = -1
Query: 203 ATRVYLILEYAP-LGTVYRELQKLSKFDEQRTATYITELANALSYCHS--KRVIHRDIKP 259
AT L +P + T Q L T + +L AL + + +IH D+KP
Sbjct: 924 ATTCVWCLSCSPTISTTCYATQTLEGVSLNLTRKFAQQLCTALLFLATPEMNIIHCDLKP 745
Query: 260 ENLLLGSA--GELKIADFGWSVHAPSSRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGV 317
EN+LL + +KI DFG S R + Y PE++ G +D +D+WSLG
Sbjct: 744 ENILLCNPKRSAIKIVDFGSSCQL-GQRIYQYIQSRFYRSPEVLLGVPYDLAIDMWSLGC 568
Query: 318 LCYEFLVGKPPF 329
+ E G+PP
Sbjct: 567 ILVEMHTGEPPL 532
>12672
Length = 773
Score = 54.7 bits (130), Expect = 5e-08, Method: Compositional matrix adjust.
Identities = 33/91 (36%), Positives = 45/91 (49%), Gaps = 6/91 (6%)
Frame = +3
Query: 241 ANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTT------LCGTLD 294
A+ + Y + +HRDIK N+LL S K+ DF V APS T + GT
Sbjct: 21 ASGIQYLNDNGHVHRDIKTANILLDSEYTAKVGDFATVVSAPSGEGKTVQNASVVIGTAA 200
Query: 295 YLPPEMIEGRMHDEKVDLWSLGVLCYEFLVG 325
YL PE I + K+D +S GV+ E + G
Sbjct: 201 YLAPEAIHFDV-STKLDSYSFGVVLLEVITG 290
>18663
Length = 600
Score = 53.5 bits (127), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 21/44 (47%), Positives = 30/44 (68%)
Frame = +2
Query: 287 TTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFE 330
+T CGT +Y+ PE++ G + VD W+LGVL YE L G+ PF+
Sbjct: 2 STFCGTPNYIAPEILRGEDYGFSVDWWALGVLLYEMLAGRSPFD 133
>11185
Length = 473
Score = 52.4 bits (124), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 30/110 (27%), Positives = 48/110 (43%), Gaps = 24/110 (21%)
Frame = +1
Query: 240 LANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFG----------------------W 277
L L Y HS ++ D++P +LL ++G LK ADFG W
Sbjct: 28 LVTGLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQW 207
Query: 278 SVHAPSS--RRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVG 325
++ + ++ G+ Y+ PE+ +G DLW+LG + YE G
Sbjct: 208 NIQSAEEMMKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSG 357
>25019
Length = 730
Score = 52.4 bits (124), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 25/59 (42%), Positives = 35/59 (59%), Gaps = 2/59 (3%)
Frame = +3
Query: 260 ENLLLGSAGELKIADFGWSVHAPSSRRTT--LCGTLDYLPPEMIEGRMHDEKVDLWSLG 316
EN+LL G +K+ DFG A + R T CGT++Y+ PE++ H + VD WSLG
Sbjct: 261 ENVLLDKDGHVKLTDFGLCKEAITGTRVTHTFCGTIEYMAPEILTRTGHGKAVDWWSLG 437
>37602
Length = 804
Score = 48.5 bits (114), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 32/99 (32%), Positives = 46/99 (46%), Gaps = 3/99 (3%)
Frame = -1
Query: 189 RHPNILRLYGYFHDATR---VYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALS 245
R NI GYF R +++ +EY G++ E + A E L
Sbjct: 354 RIVNIQTFVGYFDSYLRREKLWIAMEYCGGGSMQDIYHVTGPLTEPQIAFVCRETLKGLH 175
Query: 246 YCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSS 284
Y H + +HRDIK N+LL G++K+ADF W V + S
Sbjct: 174 YLHRRGKMHRDIKGANILLTEEGDVKLADF-WRVSSNHS 61
>07291
Length = 833
Score = 47.8 bits (112), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 25/97 (25%), Positives = 50/97 (51%), Gaps = 6/97 (6%)
Frame = +1
Query: 239 ELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHA-PSSRRTT----LCGTL 293
++A+ ++Y +V+HR++ N ++ G L+++D+G + P S T +
Sbjct: 73 QIADGMAYLQEVKVVHRNLAARNCIVTEDGRLQLSDYGVTGSLFPQSYYTADDSPARDLV 252
Query: 294 DYLPPEMIEGRMHDEKVDLWSLGVLCYEFLV-GKPPF 329
++ PE I+ K D+W+ GV+ +E L G P+
Sbjct: 253 KWMAPETIDNFHFSSKSDVWAFGVVLWELLTRGITPY 363
>01106
Length = 878
Score = 46.6 bits (109), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 46/147 (31%), Positives = 70/147 (47%), Gaps = 15/147 (10%)
Frame = +3
Query: 133 FEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQ--LEKAGVEHQLRREVEIQSHLRH 190
+ + R LG G F V+L + K +ALKV+ AQ E A E +L + V +S +
Sbjct: 324 YHVIRKLGWGHFSTVWLCWDLTCKRFVALKVVKSAQHYTETALDEVKLLKCVR-ESDVAD 500
Query: 191 PNILRLYGYFHD-------ATRVYLILEYAPLGTVYRELQKLSKFDEQRTATY-----IT 238
P + D T V ++ E LG Y L+ + + + Q + I
Sbjct: 501 PARAKCVQLLDDFKISGVNGTHVAMVFEV--LG--YNLLKLIIRSNYQGIPIHNVKLIIR 668
Query: 239 ELANALSYCHSK-RVIHRDIKPENLLL 264
++ LSY H+K R+IH DIKPEN+L+
Sbjct: 669 QVLEGLSYMHAKCRIIHTDIKPENILI 749
>18481
Length = 437
Score = 45.1 bits (105), Expect = 4e-05, Method: Compositional matrix adjust.
Identities = 38/119 (31%), Positives = 57/119 (47%), Gaps = 7/119 (5%)
Frame = -1
Query: 167 AQLEKAGVEHQL-RREVEIQSHL-RHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQK 224
++E V+HQL E ++ + RHP + +Y Y + L++E LG EL
Sbjct: 395 VKIEAIDVKHQLLHYEAKVYEQIGRHPGLPTMYHYGTEKHFNALVME--LLGPSLEELFV 222
Query: 225 LSK--FDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLG---SAGELKIADFGWS 278
+ K F + +L + L + H K IHRD+KP+N L+G L I DFG S
Sbjct: 221 ICKRRFTLKTILMVSDQLLSRLEFIHQKCFIHRDLKPDNFLMGLGRHCHRLYIIDFGLS 45
>32957
Length = 645
Score = 44.7 bits (104), Expect = 5e-05, Method: Compositional matrix adjust.
Identities = 20/60 (33%), Positives = 32/60 (53%)
Frame = +3
Query: 275 FGWSVHAPSSRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTY 334
F V R T CGT +Y+ PE+ E + + ++VD W LG+L +E L + ++ Y
Sbjct: 3 FALCVEKSGGRTRTFCGTREYMAPEVHERKEYGKEVDWWGLGILLHELLAAQIKKHSSCY 182
>07833
Length = 1504
Score = 44.7 bits (104), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 36/171 (21%), Positives = 71/171 (41%), Gaps = 16/171 (9%)
Frame = -3
Query: 188 LRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKF--DEQRTATYITELANALS 245
HPN+L + + + LI ++ P G++Y L S D+ ++ + ++A +
Sbjct: 1448 FNHPNVLPVLACCNQPPNLVLISQFMPFGSLYNTLHGESGIVVDQNQSLRFAMDIARGME 1269
Query: 246 YCHSKRVIHRDIKPE--NLLLGS---------AGELKIADFGWSVHAPSSRRTTLCGTLD 294
+ HS ++P N LL S + +AD+ +S H +
Sbjct: 1268 FLHS-------MEPTIPNFLLTSKHVMIDEDLTARINMADYCFSFHEKGKVYSP-----A 1125
Query: 295 YLPPEMIEGRMHD---EKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRIS 342
++ PE ++ R D D+WS +L +E + PF + E +++
Sbjct: 1124 WMAPEALQRRPDDINTRAADMWSFAILMWELETREVPFAELSSMEVGMKVA 972
>31489
Length = 329
Score = 43.9 bits (102), Expect = 9e-05, Method: Composition-based stats.
Identities = 23/88 (26%), Positives = 43/88 (48%), Gaps = 6/88 (6%)
Frame = +3
Query: 182 VEIQSHLRHPNI------LRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTAT 235
++I H +H NI L+ +HD ++++ + ++R + E+
Sbjct: 3 IKILKHFKHDNIISIREILKPKDSYHDFKDIHVVFDLME-SDLHRIIYSDQPLTEEHIRY 179
Query: 236 YITELANALSYCHSKRVIHRDIKPENLL 263
++ ++ L Y HS V+HRD+KP NLL
Sbjct: 180 FLYQILRGLKYIHSANVVHRDLKPSNLL 263
>17253
Length = 483
Score = 43.9 bits (102), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 27/115 (23%), Positives = 54/115 (46%), Gaps = 13/115 (11%)
Frame = -1
Query: 177 QLRREVEIQSHL-RHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQK--------LSK 227
+ RE+ I L RHPN++ G + +++E+ G + L+K L+
Sbjct: 411 EFLRELSIMRKLPRHPNVVSFMGCCTMSDPALILMEFCCHGDLLSFLRKRRPDRTVFLTS 232
Query: 228 FDEQRTA----TYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS 278
TA ++ +A +++ + +++HRD+ N+L+ K++DFG S
Sbjct: 231 TANDLTARDFFSFALHVARGMAHVANNKIVHRDVAARNVLISERNVCKVSDFGLS 67
>16708
Length = 1397
Score = 43.5 bits (101), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 39/149 (26%), Positives = 60/149 (40%), Gaps = 11/149 (7%)
Frame = -1
Query: 139 LGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNIL-RLY 197
LGKG FG VY AR L KA L+ + + H EVE + L +++
Sbjct: 1379 LGKGVFGKVYEAR--------LLSTHEKAALKTSILCHHSLDEVEALGRIEGGFYLAQMF 1224
Query: 198 GY------FHDATRVYLILEYAPLGTVYRELQK----LSKFDEQRTATYITELANALSYC 247
G F + E PL VY + + + + AL +
Sbjct: 1223 GAWVTCLPFPKMNILLHFYEMGPLCNVYAHYKNKEMPIRWSNPAMVCCIAGQXVCALEHI 1044
Query: 248 HSKRVIHRDIKPENLLLGSAGELKIADFG 276
H V+H D+K +N+L+ + G K+ D+G
Sbjct: 1043 HELGVVHMDVKADNVLVDAHGNCKLTDYG 957
>20640
Length = 1492
Score = 43.5 bits (101), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 28/94 (29%), Positives = 47/94 (50%), Gaps = 5/94 (5%)
Frame = +1
Query: 253 IHRDIKPENLLLGSAGELKIADFGW--SVHAPSSRRTTLCGT--LDYLPPEMIEGRMHDE 308
+HRD+ N L+G +KI+DFG SVH+ R + + ++P E I
Sbjct: 10 VHRDLATRNCLVGHDLVVKISDFGLARSVHSVDYYRGSEHDAIPIRWMPLEAILYNKFST 189
Query: 309 KVDLWSLGVLCYE-FLVGKPPFEANTYQETYKRI 341
+ D+WS GV+ +E F P+ T++E + +
Sbjct: 190 QSDVWSFGVVLWEIFAFALQPYYGLTHEEVVRFV 291
>07836
Length = 1478
Score = 42.7 bits (99), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 49/195 (25%), Positives = 85/195 (43%), Gaps = 31/195 (15%)
Frame = -1
Query: 159 LALKVLFKAQLEKAGVEHQLRREVEIQSH--LRHPNILRLYGY----FHDATRVYLILEY 212
+A+K+ F + E RE E+ LRH NIL T+++LI +Y
Sbjct: 1469 VAVKIFFTTE------EASWFRETELYQTVLLRHENILGFIAADIKGTGSWTQLFLITDY 1308
Query: 213 APLGTVYRELQKLSK-FDEQRTATYITELANALSYCHSK--------RVIHRDIKPENLL 263
G+++ L LS+ D L++ H + + HRDIK +N+L
Sbjct: 1307 HENGSLHDYL--LSRVLDSSEMLALAHSAICGLAHLHIEIFGTRGKPAIAHRDIKSKNIL 1134
Query: 264 LGSAGELKIADFGWSVH----------APSSRRTTLCGTLDYLPPEMIEGRMHD------ 307
+ G IAD G +V AP+ R+ GT Y+ PE++E ++
Sbjct: 1133 VKKNGTCCIADLGLAVRYISESNEVDVAPNPRQ----GTKRYMAPEVLEMLLNVKNFDAF 966
Query: 308 EKVDLWSLGVLCYEF 322
++ D+++ G++ +E
Sbjct: 965 KQADMYAFGLVMWEI 921
>17300
Length = 480
Score = 42.7 bits (99), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 30/101 (29%), Positives = 47/101 (46%), Gaps = 7/101 (6%)
Frame = +1
Query: 253 IHRDIKPENLLLGSAGELKIADFGWSVHAPSSRR----TTLCGTL--DYLPPEMIEGRMH 306
+HRD+ N+L+ K+ADFG S S TT G + + PE I R
Sbjct: 40 VHRDLAARNILVNEILVCKVADFGLSREIESDTTEGAYTTKGGKIPVRWTAPEAIAYRKF 219
Query: 307 DEKVDLWSLGVLCYEFL-VGKPPFEANTYQETYKRISRVRR 346
D+WS GV+ +E + G+ P+ + Q+ K + + R
Sbjct: 220 TSASDVWSFGVVMWEVMSYGERPYWNWSNQDVIKAVEKGYR 342
>20559
Length = 430
Score = 40.0 bits (92), Expect(2) = 2e-04, Method: Compositional matrix adjust.
Identities = 22/81 (27%), Positives = 45/81 (55%)
Frame = -2
Query: 130 LEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLR 189
++ +E +G+G +G V+ A+ +++ I+ALK + + + GV RE+ + L+
Sbjct: 378 MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRV-RLDDDDEGVPSSALREICLLKELK 202
Query: 190 HPNILRLYGYFHDATRVYLIL 210
H NI+RL+ H ++ L+
Sbjct: 201 HRNIVRLHDVLHSERKLTLVF 139
Score = 21.9 bits (45), Expect(2) = 2e-04, Method: Compositional matrix adjust.
Identities = 7/12 (58%), Positives = 9/12 (75%)
Frame = -1
Query: 244 LSYCHSKRVIHR 255
L +CHS V+HR
Sbjct: 37 LVFCHSNNVLHR 2
>38560
Length = 479
Score = 42.4 bits (98), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 20/45 (44%), Positives = 27/45 (60%), Gaps = 1/45 (2%)
Frame = -3
Query: 287 TTLCGTLDYLPPEMIEGRMH-DEKVDLWSLGVLCYEFLVGKPPFE 330
TT CG+ Y PE+I G + + D+WS+GVL Y L G PF+
Sbjct: 411 TTCCGSPAYAAPELISGLEYLGSEADIWSMGVLLYALLCGYLPFD 277
>27274
Length = 396
Score = 42.0 bits (97), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 16/32 (50%), Positives = 22/32 (68%)
Frame = -1
Query: 299 EMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFE 330
E++ G+ H VD+WSLG+L +E L G PFE
Sbjct: 375 ELLRGQQHGPTVDMWSLGILLHELLSGHVPFE 280
>20152
Length = 445
Score = 41.6 bits (96), Expect = 5e-04, Method: Compositional matrix adjust.
Identities = 20/49 (40%), Positives = 28/49 (57%), Gaps = 1/49 (2%)
Frame = +1
Query: 298 PEMIEGRMHDE-KVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVR 345
PE++ G +D VD+WSLGV+ Y +VG+ PF+ ET I R
Sbjct: 1 PEILLGDSYDAPAVDVWSLGVILYMLVVGEAPFQEANDSETLTMIMDCR 147
>11404
Length = 563
Score = 41.2 bits (95), Expect = 7e-04, Method: Compositional matrix adjust.
Identities = 42/150 (28%), Positives = 71/150 (47%), Gaps = 12/150 (8%)
Frame = +1
Query: 127 QWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKV-------LFKAQLEKAGVEHQLR 179
+WA + +EI +GKG FG V A + +A+K+ L +AQ+E +E R
Sbjct: 130 KWA-DRYEIDSLIGKGSFGQVVKAYDHTDNEQVAIKIIKNKKPFLNQAQIEVKLLEMMNR 306
Query: 180 REVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKF---DEQRTATY 236
+ + + + I+RL +F R +L L + L +L + + F T +
Sbjct: 307 HDTDNKYY-----IVRLKRHF--MFRSHLCLVFELLSYNLYDLLRNTNFRGVSLNLTRKF 465
Query: 237 ITELANALSYCHS--KRVIHRDIKPENLLL 264
+L AL + + +IH D+KPEN+LL
Sbjct: 466 AQQLCTALLFLATPEMSIIHCDLKPENILL 555
>29590
Length = 320
Score = 38.9 bits (89), Expect = 0.003, Method: Composition-based stats.
Identities = 17/41 (41%), Positives = 24/41 (58%)
Frame = +3
Query: 289 LCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPF 329
+ GT DY+ PE+++ + D+WSLGVL Y L PF
Sbjct: 54 IIGTPDYVAPEVLDYEPLSIQTDMWSLGVLSYVMLTACSPF 176
>32000
Length = 644
Score = 38.5 bits (88), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 26/80 (32%), Positives = 39/80 (48%), Gaps = 3/80 (3%)
Frame = -1
Query: 267 AGELKIADFGWS--VHAPSSRRTTLCGTLDYLPPEMIEG-RMHDEKVDLWSLGVLCYEFL 323
++KIADFG + P T TL Y PE++ G R + VD+WSLG + E +
Sbjct: 581 TAKMKIADFGLARVFGLPVRTYTHEVITLWYRAPEILLGCRFYSVPVDIWSLGCIFVEMM 402
Query: 324 VGKPPFEANTYQETYKRISR 343
+ F ++ + RI R
Sbjct: 401 TRRALFPGDSEIDQLYRIFR 342
>00638
Length = 1595
Score = 38.1 bits (87), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 15/37 (40%), Positives = 21/37 (56%)
Frame = +2
Query: 223 QKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKP 259
Q F + Y+ EL AL +CHS ++HRD+KP
Sbjct: 392 QLYQTFTDYDIRFYLYELMKALDFCHSMGIMHRDVKP 502
>02638
Length = 1490
Score = 37.7 bits (86), Expect = 0.008, Method: Compositional matrix adjust.
Identities = 14/56 (25%), Positives = 29/56 (51%)
Frame = +1
Query: 289 LCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRV 344
L GT+ ++ PE++ G + D+WS+G + E +PP+ ++ I ++
Sbjct: 16 LLGTIAFMAPEVLRGESYGRACDVWSVGCVMIEMCTCRPPWNSHDISNHLALIFKI 183
>31789
Length = 676
Score = 36.6 bits (83), Expect = 0.013, Method: Compositional matrix adjust.
Identities = 27/103 (26%), Positives = 45/103 (43%), Gaps = 5/103 (4%)
Frame = +2
Query: 132 DFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHP 191
D EIGR G F VY + + +A L + K + + E E+ L+HP
Sbjct: 335 DVEIGR----GSFKTVYKGLDTELGVAVAWCELQDKKWNKT-ERQRFKEEAEMLKELQHP 499
Query: 192 NILRLYGYFHDATR-----VYLILEYAPLGTVYRELQKLSKFD 229
NI+R + Y+ + + L+ E GT+ L++ K +
Sbjct: 500 NIVRFFDYWEEHNHRNRKVIILVTELMTSGTLKTYLKRFKKIN 628
>37063
Length = 455
Score = 35.4 bits (80), Expect = 0.038, Method: Compositional matrix adjust.
Identities = 23/77 (29%), Positives = 41/77 (53%), Gaps = 15/77 (19%)
Frame = -2
Query: 257 IKPENLLLGSAGE---LKIADF----GWSVHAPSSRRTTL---CGTLDYLPPEMIEGRM- 305
+KPEN+L E LKI DF G + ++ L G+ +Y+ PE+++ +
Sbjct: 454 LKPENILCEHLDEVVPLKICDFDLASGINCDGDGTKTPELLTPVGSAEYMAPEVVDAWVG 275
Query: 306 ----HDEKVDLWSLGVL 318
+D++ D+WSLG++
Sbjct: 274 ESFSYDKRCDMWSLGII 224
>00394
Length = 548
Score = 34.7 bits (78), Expect = 0.056, Method: Compositional matrix adjust.
Identities = 23/96 (23%), Positives = 43/96 (44%), Gaps = 5/96 (5%)
Frame = -2
Query: 135 IGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNIL 194
+ +G+G F VY + + +A L + KA + + E E+ L+HPNI+
Sbjct: 286 FDKEIGRGSFKTVYKGLDTELGVAVAWCELQDKKWNKAE-RQRFKEEAEMLKELQHPNIV 110
Query: 195 RLYGYFHDATR-----VYLILEYAPLGTVYRELQKL 225
R + Y+ + + L+ E GT+ L++
Sbjct: 109 RFFDYWEEHNHRNRKVIILVTELMTSGTLKTYLKRF 2
>18401
Length = 463
Score = 32.0 bits (71), Expect = 0.36, Method: Compositional matrix adjust.
Identities = 15/58 (25%), Positives = 27/58 (46%)
Frame = -3
Query: 287 TTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRV 344
+T+ T Y PE+I D+WS+G + +E G F+ + +E + R+
Sbjct: 458 STIVSTRHYRAPEVILELGWSHPCDVWSVGCIMFELYTGYTLFQTHDNKEHLAMMERI 285
>36481
Length = 806
Score = 32.0 bits (71), Expect = 0.38, Method: Compositional matrix adjust.
Identities = 32/141 (22%), Positives = 65/141 (46%), Gaps = 8/141 (5%)
Frame = +2
Query: 132 DFEIGRPLGKGKFGNVYLAREKQSKFILALKVL--FKAQLEKAGVE-HQLRREVEIQSHL 188
D ++ G+G FG V ++ +ALK++ E A +E + L + E H
Sbjct: 365 DMKLCPHWGEGTFGKVVQCKDLLKGDDIALKIIKNVDKYREAAKLEINVLEKLREKDPHA 544
Query: 189 RHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKF-----DEQRTATYITELANA 243
+H + L + + ++ + + LG + K + + ++ R +Y +L A
Sbjct: 545 KHMCVQMLDWFDYHG---HVCISFHMLGLSVFDFLKDNSYGAYPIEQVRHISY--QLCYA 709
Query: 244 LSYCHSKRVIHRDIKPENLLL 264
+++ H ++ H D+KPEN+L
Sbjct: 710 VNFLHENQLTHTDLKPENILF 772
>21800
Length = 855
Score = 32.0 bits (71), Expect = 0.39, Method: Compositional matrix adjust.
Identities = 17/46 (36%), Positives = 26/46 (56%), Gaps = 5/46 (10%)
Frame = +2
Query: 237 ITELANALSYCHSK-RVIHRDIKPENLLLGSAG----ELKIADFGW 277
I ++ L+Y H+K +IH DIKPEN+L+ +L + F W
Sbjct: 650 IRQVLEGLNYLHAKCNIIHTDIKPENILICVDDNYIRKLAVDAFEW 787
>21210
Length = 518
Score = 32.0 bits (71), Expect = 0.40, Method: Compositional matrix adjust.
Identities = 15/43 (34%), Positives = 23/43 (53%), Gaps = 4/43 (9%)
Frame = +3
Query: 291 GTLDYLPPEMIEGRM----HDEKVDLWSLGVLCYEFLVGKPPF 329
G Y+ PE I+ R +D + D+WSLG+ E G+ P+
Sbjct: 6 GCRPYMAPERIDPRASSHGYDVRSDVWSLGITLMELATGRFPY 134
>31120
Length = 439
Score = 31.2 bits (69), Expect = 0.72, Method: Compositional matrix adjust.
Identities = 15/33 (45%), Positives = 22/33 (66%), Gaps = 1/33 (3%)
Frame = +1
Query: 299 EMIEGRMHDEKV-DLWSLGVLCYEFLVGKPPFE 330
E++ G +D K+ D WSLGV+ + L GK PF+
Sbjct: 1 EVVCGVPYDPKMADAWSLGVILFIMLNGKMPFD 99
>17932
Length = 597
Score = 30.4 bits (67), Expect = 1.0, Method: Compositional matrix adjust.
Identities = 15/37 (40%), Positives = 18/37 (48%), Gaps = 2/37 (5%)
Frame = -2
Query: 313 WSLGVLCYEFLVGKPPF--EANTYQETYKRISRVRRN 347
WSLGV YE L G PF + + TY I + N
Sbjct: 593 WSLGVCAYEMLFGCTPFTDDDGSMVATYNNIMNYKTN 483
>17637
Length = 447
Score = 27.3 bits (59), Expect = 9.5, Method: Compositional matrix adjust.
Identities = 15/43 (34%), Positives = 26/43 (60%), Gaps = 2/43 (4%)
Frame = +1
Query: 295 YLPPEMIEGRMHDEKVDLWSLGVLCYEFL-VGKPPF-EANTYQ 335
+L E ++ ++E D+WS GVL +E +GK P+ E + Y+
Sbjct: 115 WLSLEALQKSHYNEGSDVWSFGVLMWEMCTLGKLPYAEIDPYE 243
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000359685 | hsapiens_gene_ensembl | Protein
tyrosine phosphatase type IVA protein 1 (EC 3.1.3.48)
(Protein-tyrosine phosphatase 4a1) (Protein-tyrosine phosphatase of
regenerating liver 1) (PRL-1) (PTP(CAAXI)).
[Source:Uniprot/SWISSPROT;Acc:Q93096]
(173 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
14057 236 5e-63
25697 212 7e-56
30741 35 0.013
19962 32 0.19
29613 30 0.35
15655 30 0.48
11098 29 0.81
>14057
Length = 1377
Score = 236 bits (601), Expect = 5e-63, Method: Compositional matrix adjust.
Identities = 107/170 (62%), Positives = 137/170 (80%)
Frame = +2
Query: 3 RMNRPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEKEG 62
+ RP P E+ +KNMRFLIT PT++T++K+IEEL+K+G +VRVC+ TY +++K G
Sbjct: 665 KARRPEPAEIEFKNMRFLITDRPTDSTIDKYIEELQKHGAKHVVRVCDPTYSREVLQKAG 844
Query: 63 IHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALIEG 122
I VLDW FDDG+PP N++V +W +L+K +F+EEPGCC+AVHCVAGLGRAPVLVA+AL+E
Sbjct: 845 IDVLDWQFDDGSPPPNEVVGNWFNLLKARFKEEPGCCVAVHCVAGLGRAPVLVAIALMEA 1024
Query: 123 GMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFKDSNGHRNNCCI 172
GMKYEDAV+ IRQKRRGA NSKQL YL+ YRPK RLR + NGH + C I
Sbjct: 1025GMKYEDAVELIRQKRRGAINSKQLSYLQHYRPKSRLR-HNRNGH-SQCLI 1168
>25697
Length = 470
Score = 212 bits (539), Expect = 7e-56, Method: Compositional matrix adjust.
Identities = 96/150 (64%), Positives = 121/150 (80%), Gaps = 1/150 (0%)
Frame = +1
Query: 18 RFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEKEGIHVLDWPFDDGAPPS 77
RFLIT PT++TL+KFIEEL+K+G +VRVC+ TY +E EGI V+DW FDDG+PP
Sbjct: 1 RFLITDRPTDSTLDKFIEELQKHGARHVVRVCDPTYSKEKLETEGIDVMDWQFDDGSPPP 180
Query: 78 NQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALIEGGMKYEDAVQFIRQKR 137
+V +W +L+K F+++PGCC+AVHCVAGLGRAPVLVA+AL+E GMKYEDAV+ IR+KR
Sbjct: 181 KDVVGNWFNLLKASFKDDPGCCVAVHCVAGLGRAPVLVAIALMEAGMKYEDAVELIRRKR 360
Query: 138 RGAFNSKQLLYLEKYRPKMRLRFK-DSNGH 166
RGA NSKQL YL+ YRP+ RLR K + NGH
Sbjct: 361 RGAINSKQLSYLQHYRPRSRLRSKANRNGH 450
>30741
Length = 506
Score = 35.4 bits (80), Expect = 0.013, Method: Compositional matrix adjust.
Identities = 17/54 (31%), Positives = 26/54 (48%)
Frame = -3
Query: 64 HVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVAL 117
H + WP D G P ++ +++S V+ VHC AG+GR +AL
Sbjct: 405 HFMRWP-DHGCPERTSMLLNFVSSVRAHMPHTGAGPTLVHCSAGVGRTGTFIAL 247
>19962
Length = 410
Score = 31.6 bits (70), Expect = 0.19, Method: Compositional matrix adjust.
Identities = 24/80 (30%), Positives = 34/80 (42%)
Frame = +1
Query: 59 EKEGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALA 118
E +H WP D G P +V W S V + + G + VHC AG+GR +AL
Sbjct: 127 EVHLLHFTAWP-DHGVPCPVTLVRFW-SYVTRQPAQLSGPLL-VHCSAGIGRTGTYIALD 297
Query: 119 LIEGGMKYEDAVQFIRQKRR 138
++ + V RR
Sbjct: 298 MLTHQAETTGKVSVFPTVRR 357
>29613
Length = 425
Score = 30.4 bits (67), Expect = 0.35, Method: Compositional matrix adjust.
Identities = 18/55 (32%), Positives = 25/55 (45%), Gaps = 2/55 (3%)
Frame = -2
Query: 82 DDWLSLVKIKFREEPGCC--IAVHCVAGLGRAPVLVALALIEGGMKYEDAVQFIR 134
DD L + E GC + VHC AG+GR +AL + +QF+R
Sbjct: 241 DDVLDFISSVRLESRGCQGPMVVHCSAGVGRTGTFIALDFL---------MQFVR 104
>15655
Length = 467
Score = 30.0 bits (66), Expect = 0.48, Method: Compositional matrix adjust.
Identities = 24/100 (24%), Positives = 41/100 (41%), Gaps = 11/100 (11%)
Frame = +1
Query: 31 NKFIEELKKYGVTTIVRVCEATYDTTLVEKEGIHVLDWPFDDGAPPSNQIVDDWLSLVKI 90
NK ++ K Y T ++ T E + + WP D G PP+ +D + ++
Sbjct: 88 NKSVQTYKNYVETKLI--LRNTETDEWREVTHLQFISWP-DYGIPPATGFLDFLFHVREV 258
Query: 91 K----------FREEP-GCCIAVHCVAGLGRAPVLVALAL 119
+ + P G I VHC AG+GR + + +
Sbjct: 259 QASATTKMGASWAGHPLGPPIVVHCSAGIGRTGTFITIDI 378
>11098
Length = 1151
Score = 29.3 bits (64), Expect = 0.81, Method: Compositional matrix adjust.
Identities = 18/62 (29%), Positives = 35/62 (56%), Gaps = 3/62 (4%)
Frame = -3
Query: 31 NKFIEELKKYGVTTIVRVCEATYDTTL--VEKEGIHVLDWPFDDGAPPSNQI-VDDWLSL 87
N+F+ +K + V I+ C T+D L EK+ ++V + +G+P + VD+ +SL
Sbjct: 948 NEFVPFIKNFDVDEIMNFCTFTFDKQLFGTEKDVLYVCTYVPPEGSPFYSHFGVDNGISL 769
Query: 88 VK 89
++
Sbjct: 768 LE 763
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000317334 | hsapiens_gene_ensembl | T-complex
protein 1 subunit alpha (TCP-1-alpha) (CCT-alpha).
[Source:Uniprot/SWISSPROT;Acc:P17987]
(556 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
05356 137 8e-63
01159 236 2e-62
29631 116 9e-50
09900 154 1e-37
06409 135 5e-32
29864 127 1e-29
12796 119 4e-27
33770 92 4e-19
30661 59 7e-09
25854 57 2e-08
17249 55 1e-07
31574 30 2.7
>05356
Length = 2339
Score = 137 bits (345), Expect(2) = 8e-63, Method: Compositional matrix adjust.
Identities = 89/272 (32%), Positives = 153/272 (56%), Gaps = 1/272 (0%)
Frame = +2
Query: 20 QNVMAAASIANIVKSSLGPVGLDKMLVDDIGDVTITNDGATILKLLEVEHPAAKVLCELA 79
+N+ A +A +S+ GP G +KM+++ + + +TND ATIL+ LEV+HPAAK+L A
Sbjct: 281 RNIEACKELAKTTRSAYGPHGQNKMVINHLEKLFVTNDAATILRELEVQHPAAKMLVLAA 460
Query: 80 DLQDKEVGDGTTSVVIIAAELLKNADELVKQKIHPTSVISGYRLACKEAVRYINENLIVN 139
Q++E GDGT V++ A LL+NA++L++ + T VI GY LA K+A + + +I +
Sbjct: 461 HQQEQECGDGTNFVLVFAGALLENAEQLLRMGLSVTEVIEGYELALKKAHEILPKLVIGH 640
Query: 140 TDEL-GRDCLINAAKTSMSSKIIGINGDFFANMVVDAVLAIKYTDIRGQPRYPVNSVNIL 198
L ++ + A +TS+ SK G N DF A+++ DA +++ + + + V++V +
Sbjct: 641 VKNLRNKEEVKTAIRTSVMSKQYG-NEDFLADLITDACVSV----LPAKISFSVDNVRVC 805
Query: 199 KAHGRSQMESMLISGYALNCVVGSQGMPKRIVNAKIACLDFSLQKTKMKLGVQVVITDPE 258
K G ++S I G V +G ++ AK+A L + + V+I + E
Sbjct: 806 KILGCGLLQSSTIQGMVFKRQV--EGEITKVEKAKVAVFTCPLDSMQTETKGTVLIKNAE 979
Query: 259 KLDQIRQRESDITKERIQKILATGANVILTTG 290
+L + E D+ +E+I+ I G NVI+ G
Sbjct: 980 ELMSFSKGEEDMMEEQIKGIKEAGVNVIVAGG 1075
Score = 122 bits (305), Expect(2) = 8e-63, Method: Compositional matrix adjust.
Identities = 79/250 (31%), Positives = 128/250 (51%), Gaps = 2/250 (0%)
Frame = +1
Query: 288 TTGGIDDMCLKYFVEAGAMAVRRVLKRDLKRIAKASGATILSTLANLEGEETFEAAMLGQ 347
+ G + D+ Y + M +R + K DL+R+ K+ AT L + EE G
Sbjct: 1066 SWGEVGDLAQHYCNKYKVMVIRLLSKWDLRRLCKSICATALPKVTTPRNEEC------GY 1227
Query: 348 AEEVVQERICDDELILIKNTKARTS-ASIILRGANDFMCDEMERSLHDALCVVKRVLESK 406
+ V + I + +++ + K + ++I+RG+ D + D++ER+L D + K + +
Sbjct: 1228 CDLVYVDEIGETPVVIFQQNKDESPITTVIIRGSTDNIMDDIERALDDGVNTFKALTKDD 1407
Query: 407 SVVPGGGAVEAALSIYLENYATSMGSREQLAIAEFARSLLVIPNTLAVNAAQDSTDLVAK 466
+VPG GA E L+ + Y S+ EQ A+ +FA SL VIP LA N +TD+++K
Sbjct: 1408 RLVPGAGATEIELAKQITTYGESLPGLEQYAVKKFAESLEVIPRALAENTGMKATDILSK 1587
Query: 467 LRAFHNEAQVNPERKNLKWIGLDLSN-GKPRDNKQAGVFEPTIVKVKSLKFATEAAITIL 525
L A H E Q N G+D+ + G D KQA + + + + LKFA AA T+L
Sbjct: 1588 LYAAHQEGQQNA--------GVDIDDSGSVLDAKQANLTDLYLNRYWGLKFAAAAACTVL 1743
Query: 526 RIDDLIKLHP 535
R+D +I P
Sbjct: 1744 RVDQIIMAKP 1773
>01159
Length = 2613
Score = 236 bits (601), Expect = 2e-62, Method: Compositional matrix adjust.
Identities = 170/526 (32%), Positives = 287/526 (54%), Gaps = 6/526 (1%)
Frame = +3
Query: 11 RSTGETIRSQNVMAAASIANIVKSSLGPVGLDKMLVDDIGDVTITNDGATILKLLEVEHP 70
R TG +++AA S+A+I+K+SLGP GLDKM+V GDVT+TNDGATIL +++V+H
Sbjct: 171 RLTGIEAHKSHILAAKSVASILKTSLGPKGLDKMMVSGDGDVTVTNDGATILDMMDVDHQ 350
Query: 71 AAKVLCELADLQDKEVGDGTTSVVIIAAELLKNADELVKQKIHPTSVISGYRLACKEAVR 130
AK++ +L+ QD E+GDGTT VV++A LL+ A++L+ + IHP + GY +A K AV
Sbjct: 351 IAKLMVQLSKSQDDEIGDGTTGVVVLAGALLEQAEKLLDRGIHPIRIADGYEIAAKCAVE 530
Query: 131 Y---INENLIVNTDELGRDCLINAAKTSMSSKIIGINGDFFANMVVDAVLAIKYTDIRGQ 187
I++N V D + LI A T++ SKI+ A + VDA++++ D++
Sbjct: 531 TLDKISDNYEV--DLKNAEPLIKLAMTTLGSKIVNRCHRQMAKIAVDAIMSV--ADLK-- 692
Query: 188 PRYPVNSVNILKAHGR--SQME-SMLISGYALNCVVGSQGMPKRIVNAKIACLDFSLQKT 244
R V+ ++K G+ ++E +ML+ G ++ + MPK + +AKIA L +
Sbjct: 693 -RKDVD-FELIKVEGKVGGKLEDTMLVKGVVVDKDMSHPQMPKVVKDAKIAILTCPFEPP 866
Query: 245 KMKLGVQVVITDPEKLDQIRQRESDITKERIQKILATGANVILTTGGIDDMCLKYFVEAG 304
K K ++ IT E ++R+ E + + +Q + GAN+++ G DD ++
Sbjct: 867 KPKTKHKLDITSVEDYKKLREYELNKFESMVQSVKDKGANLVICQWGFDDEANHLLLQRE 1046
Query: 305 AMAVRRVLKRDLKRIAKASGATILSTLANLEGEETFEAAMLGQAEEVVQERICDDELILI 364
AVR V +++ IA A+G I+ L E+ +A ++ + + D +++I
Sbjct: 1047LPAVRWVGGPEIELIAIATGGRIVPRFEELTTEKLGKAGIVRE----LTFGTTKDRMLVI 1214
Query: 365 KNTKARTSASIILRGANDFMCDEMERSLHDALCVVKRVLESKSVVPGGGAVEAALSIYLE 424
+ + +I +RG N + +E +RSLHDALCV++ ++ VV GGGA E A S+ +
Sbjct: 1215EECLNTRAVTIFIRGGNKMIVEEAKRSLHDALCVIRNLVRDNRVVYGGGAPEIAASVAVA 1394
Query: 425 NYATSMGSREQLAIAEFARSLLVIPNTLAVNAAQDSTDLVAKLRAFHNEAQVNPERKNLK 484
A + + EQ A+ F+ +L +P LA N+ +A++++ + + NP
Sbjct: 1395EAADKISTLEQYAVRSFSEALEAVPLALAENSGLAPIQTLAEVKSRQVKEK-NPR----- 1556
Query: 485 WIGLDLSNGKPRDNKQAGVFEPTIVKVKSLKFATEAAITILRIDDL 530
+G+D D K+ V E K + + AT+ IL+IDD+
Sbjct: 1557-LGIDCLLKGTNDMKEQNVIETLTAKKQQILLATQLVRMILKIDDI 1691
>29631
Length = 1257
Score = 116 bits (291), Expect(3) = 9e-50, Method: Compositional matrix adjust.
Identities = 53/140 (37%), Positives = 93/140 (66%)
Frame = +3
Query: 11 RSTGETIRSQNVMAAASIANIVKSSLGPVGLDKMLVDDIGDVTITNDGATILKLLEVEHP 70
R +G ++ N+ A +IA+++++ LGP + KML+D +G + +TNDG IL+ + V+HP
Sbjct: 30 RESGRKVQLGNIAAGKTIADVIRTCLGPKSMLKMLMDPMGGIVMTNDGNAILREINVQHP 209
Query: 71 AAKVLCELADLQDKEVGDGTTSVVIIAAELLKNADELVKQKIHPTSVISGYRLACKEAVR 130
AAK + E+A QD+E GDGT SV+I+A E+L A++ ++Q++HPT +I+ YR A ++ +
Sbjct: 210 AAKSMIEVARTQDEETGDGTKSVIILAGEVLSVAEQFLEQQMHPTVIIAAYRQALEDTLE 389
Query: 131 YINENLIVNTDELGRDCLIN 150
+ + D R+ ++N
Sbjct: 390 VLRTKICTPIDISDRNQMLN 449
Score = 70.1 bits (170), Expect(3) = 9e-50, Method: Compositional matrix adjust.
Identities = 49/189 (25%), Positives = 94/189 (49%), Gaps = 1/189 (0%)
Frame = +1
Query: 151 AAKTSMSSKIIGINGDFFANMVVDAVLAIKYTDIRGQPRYPVNS-VNILKAHGRSQMESM 209
++++ + +K I D + +DA + + + G+ + + K G + ES
Sbjct: 451 SSQSCLGTKFISKWMDLACQIALDATTTV-FMEENGRKEIDIKRYAKVEKIPGGTMEESE 627
Query: 210 LISGYALNCVVGSQGMPKRIVNAKIACLDFSLQKTKMKLGVQVVITDPEKLDQIRQRESD 269
++ G +N V M +RI N +I LD +L+ K + + I+ E +I Q E +
Sbjct: 628 VLKGIXVNKDVVHXKMKRRIENPRIMLLDCNLEYKKGESATNIEISKEEDFAKILQLEEE 807
Query: 270 ITKERIQKILATGANVILTTGGIDDMCLKYFVEAGAMAVRRVLKRDLKRIAKASGATILS 329
++ +I+A ++++T G+ D+ + ++AG +RRV K D RIA+A GATI +
Sbjct: 808 YIRKMCDEIIALKPDLVITEKGVSDLAQHFLLKAGISVLRRVRKTDNNRIARACGATIAN 987
Query: 330 TLANLEGEE 338
L+ E+
Sbjct: 988 RTDELKEED 1014
Score = 50.1 bits (118), Expect(3) = 9e-50, Method: Compositional matrix adjust.
Identities = 29/81 (35%), Positives = 46/81 (56%), Gaps = 1/81 (1%)
Frame = +3
Query: 341 EAAMLGQAEEVVQER-ICDDELILIKNTKARTSASIILRGANDFMCDEMERSLHDALCVV 399
E GQ ++ R I DD + + K+ + +I+LRGA+ + E+ER+L DA+ V
Sbjct: 1002 EGGRYGQWLWALEVRKIGDDYFTFLVDCKSPKACTILLRGASKDILAEVERNLQDAMNVA 1181
Query: 400 KRVLESKSVVPGGGAVEAALS 420
+ V+ + PGGGA E AL+
Sbjct: 1182 RNVMIDPHLCPGGGASEMALA 1244
>09900
Length = 1305
Score = 154 bits (388), Expect = 1e-37, Method: Compositional matrix adjust.
Identities = 95/312 (30%), Positives = 167/312 (53%)
Frame = +3
Query: 233 KIACLDFSLQKTKMKLGVQVVITDPEKLDQIRQRESDITKERIQKILATGANVILTTGGI 292
+IA L+ L+ + +V + + ++ I E I +++ KI +GA V+L+ I
Sbjct: 60 RIALLNIELELKSERDNAEVRVDNVQEYQSIVDAEWKILYDKLDKIHQSGAKVVLSKLPI 239
Query: 293 DDMCLKYFVEAGAMAVRRVLKRDLKRIAKASGATILSTLANLEGEETFEAAMLGQAEEVV 352
D+ +YF + RV + DL+R KA G +I +T+ +L + +LG +
Sbjct: 240 GDVATQYFADRDMFCAGRVPEEDLRRTMKACGGSIQTTVQSLTPD------VLGTCQLFD 401
Query: 353 QERICDDELILIKNTKARTSASIILRGANDFMCDEMERSLHDALCVVKRVLESKSVVPGG 412
+ +I + + K + +IILRG + +E ERSLHDA+ +V+R +++ SVV GG
Sbjct: 402 EIQIGGERFNMFKGCTMARTCTIILRGGAEQFMEETERSLHDAIMIVRRAIKNDSVVAGG 581
Query: 413 GAVEAALSIYLENYATSMGSREQLAIAEFARSLLVIPNTLAVNAAQDSTDLVAKLRAFHN 472
GA+E +S +L ++ ++ +EQL ++ +A++L VIP L NA D+T+++ KLR H
Sbjct: 582 GAIEMEVSYHLREHSHTIAGKEQLLMSAYAKALEVIPRQLCDNAGFDATNILNKLRQKHA 761
Query: 473 EAQVNPERKNLKWIGLDLSNGKPRDNKQAGVFEPTIVKVKSLKFATEAAITILRIDDLIK 532
+ W G+++ DN + V+EP +VK+ +L A+EA IL +D+ IK
Sbjct: 762 QGGT--------WYGVNILREDIADNFEDCVWEPAVVKINALTAASEATALILSVDETIK 917
Query: 533 LHPESKDDKHGS 544
+ D G+
Sbjct: 918 NPRSGQGDAPGA 953
>06409
Length = 1533
Score = 135 bits (339), Expect = 5e-32, Method: Compositional matrix adjust.
Identities = 86/316 (27%), Positives = 162/316 (51%), Gaps = 8/316 (2%)
Frame = -3
Query: 224 GMPKRIVNAKIACLDFSLQKTKMKLGVQVVITDPEKLDQIRQRESDITKERIQKILATGA 283
G P ++ AKI + F + K + QV+++D ++D++ + E + + ++KI G
Sbjct: 1507 GGPSKVEKAKIGFIQFCISPPKTDMENQVIVSDYTQMDRVLREERNYILDIVKKIKKAGC 1328
Query: 284 NVILTTGGI-----DDMCLKYFVEAGAMAVRRVLKRDLKRIAKASGATILSTLANLEGEE 338
NV+L I D+ L + + M V+ + + D++ + K G +++L +
Sbjct: 1327 NVLLIQKSILRDAVSDLALHFLAKMKIMVVKDIEREDVEFVCKTLGCRPVASL------D 1166
Query: 339 TFEAAMLGQAEEVVQERICDDELILIKNT---KARTSASIILRGANDFMCDEMERSLHDA 395
F LG A+ + E + ++K T + ++++RG+N + +E +RSLHDA
Sbjct: 1165 HFLPENLGSADLI--EEVQTGSSKIVKATGIANPGQTVTVLIRGSNKLVLEEADRSLHDA 992
Query: 396 LCVVKRVLESKSVVPGGGAVEAALSIYLENYATSMGSREQLAIAEFARSLLVIPNTLAVN 455
LCV++ +++ K+++ GGGA E +S+ L YA ++ EQ FA +L VIP TLA N
Sbjct: 991 LCVIRCLVKKKALIAGGGAPETEMSMRLAAYANTLAGMEQYCFRAFAEALEVIPFTLAEN 812
Query: 456 AAQDSTDLVAKLRAFHNEAQVNPERKNLKWIGLDLSNGKPRDNKQAGVFEPTIVKVKSLK 515
A + V LR H + + + G+++ G + + V +P +V ++
Sbjct: 811 AGLNPISTVTXLRTRHAQGE--------RTAGINVRKGAITNILEENVLQPLLVSTSAIT 656
Query: 516 FATEAAITILRIDDLI 531
A+E +IL+IDD++
Sbjct: 655 LASETVRSILKIDDIV 608
>29864
Length = 1026
Score = 127 bits (319), Expect = 1e-29, Method: Compositional matrix adjust.
Identities = 77/257 (29%), Positives = 138/257 (53%)
Frame = +1
Query: 21 NVMAAASIANIVKSSLGPVGLDKMLVDDIGDVTITNDGATILKLLEVEHPAAKVLCELAD 80
N+ AA + ++++S+LGP G KMLV GD+ +T DG +L ++++HP A ++ +A
Sbjct: 175 NIAAAKGLQDVLRSNLGPKGTMKMLVSGAGDIKLTKDGNVLLHEMQIQHPTASLIARVAT 354
Query: 81 LQDKEVGDGTTSVVIIAAELLKNADELVKQKIHPTSVISGYRLACKEAVRYINENLIVNT 140
QD GDGTTS V+I ELLK AD + + +HP + G+ LA +A+ + E +
Sbjct: 355 AQDDITGDGTTSNVLIIGELLKQADLYIAEGLHPRLITEGFELARNKALEVLEE--VKVK 528
Query: 141 DELGRDCLINAAKTSMSSKIIGINGDFFANMVVDAVLAIKYTDIRGQPRYPVNSVNILKA 200
E+ R+ L+ A+TS+ +K+ D VVDAVLAI+ G+ ++ V +++
Sbjct: 529 REVDRETLVQVARTSLRTKVHTELADLLTEHVVDAVLAIQXP---GEG-IDLHMVELMEM 696
Query: 201 HGRSQMESMLISGYALNCVVGSQGMPKRIVNAKIACLDFSLQKTKMKLGVQVVITDPEKL 260
++ ++S L+ G ++ M K +A I + SL+ K ++ ++
Sbjct: 697 QHKTDLDSTLVRGLVMDHGARHPDMKKHTKDAFILTCNVSLEYEKTEVNSGFFYKTAQER 876
Query: 261 DQIRQRESDITKERIQK 277
+++ + E ER++K
Sbjct: 877 EKLVEAERTFIDERVRK 927
>12796
Length = 1316
Score = 119 bits (297), Expect = 4e-27, Method: Compositional matrix adjust.
Identities = 91/346 (26%), Positives = 169/346 (48%), Gaps = 5/346 (1%)
Frame = -3
Query: 194 SVNILKAHGRSQMESMLISGYALNCVVGSQGMPKRIVNAKIACLDFSLQKTKMKLGVQVV 253
++ ++++ G + ++ L++G PKRI AKI + F + K + V+
Sbjct: 1296 NIKVIRSLGGTVEDTELVNGLVFTSRSAGTNAPKRIEKAKIGLIQFCISAPKTDMDHNVI 1117
Query: 254 ITDPEKLDQIRQRESDITKERIQKILATGANVILTTGGI-----DDMCLKYFVEAGAMAV 308
++D +D++ + E +++I G NV+L I D+ + + + V
Sbjct: 1116 VSDYAAMDRVLKEERSYILNIVKQIKKAGCNVLLVQKSILRDAVSDLAQHFLDKIKCLVV 937
Query: 309 RRVLKRDLKRIAKASGATILSTLANLEGEETFEAAMLGQAEEVVQERICDDELILIKNTK 368
+ V + D++ + K +++L + E A ++ EEV ++ I+N +
Sbjct: 936 KDVEREDIEFVCKTLHCRPIASLDHFTAENMSSADLV---EEVASGTNKFVKITGIQN-Q 769
Query: 369 ARTSASIILRGANDFMCDEMERSLHDALCVVKRVLESKSVVPGGGAVEAALSIYLENYAT 428
RT SII RG+N + +E RSLHDALCVV+ ++ +++ + GGGA E +++ L A
Sbjct: 768 GRT-VSIICRGSNKLVLEEAARSLHDALCVVRCLVRNRAQIVGGGAPEIEMALQLAAAAQ 592
Query: 429 SMGSREQLAIAEFARSLLVIPNTLAVNAAQDSTDLVAKLRAFHNEAQVNPERKNLKWIGL 488
++ + FA +L VIP+TLA NA + V +LR H + + N G+
Sbjct: 591 TVDGVDAYCYRAFADALEVIPSTLAENAGLNPIATVTELRNRHAQGEKNA--------GI 436
Query: 489 DLSNGKPRDNKQAGVFEPTIVKVKSLKFATEAAITILRIDDLIKLH 534
++ G D V +P +V ++ ATE +IL+IDD++ +
Sbjct: 435 NVRKGAITDIFAENVVQPLLVSTSAITLATETVRSILKIDDIVNTY 298
>33770
Length = 484
Score = 92.4 bits (228), Expect = 4e-19, Method: Compositional matrix adjust.
Identities = 59/131 (45%), Positives = 87/131 (66%), Gaps = 1/131 (0%)
Frame = +1
Query: 50 GDVTITNDGATILKLLEVEHPAAKVLCELADLQDKEVGDGTTSVVIIAAELLKNADELVK 109
GDVTITNDGATILK ++V HPAAK+L EL+ QD E GDGTT+VV++A LL + +L+
Sbjct: 22 GDVTITNDGATILKQMQVLHPAAKMLVELSKAQDIEXGDGTTTVVVLAGSLLDASAKLLA 201
Query: 110 QKIHPTSVISGYRLACKEAVRYINENLIVNTDELG-RDCLINAAKTSMSSKIIGINGDFF 168
+ IHPT + ++ A + V ++ +V EL R+ L+++A TS++SK++
Sbjct: 202 KGIHPTMISEAFQKAASKCVELLDG--MVKPLELSDRESLLSSASTSLNSKVVSQYSSML 375
Query: 169 ANMVVDAVLAI 179
A + VDAVL +
Sbjct: 376 APIAVDAVLKV 408
>30661
Length = 380
Score = 58.5 bits (140), Expect = 7e-09, Method: Composition-based stats.
Identities = 32/98 (32%), Positives = 51/98 (52%)
Frame = +3
Query: 341 EAAMLGQAEEVVQERICDDELILIKNTKARTSASIILRGANDFMCDEMERSLHDALCVVK 400
E LGQ + + + I +D+LI + +I+LRGA + DE RSLHDALCV+
Sbjct: 63 EKTKLGQCDLIEEVMIGEDKLIKFSGVALGEACTIVLRGATQQILDEAXRSLHDALCVLS 242
Query: 401 RVLESKSVVPGGGAVEAALSIYLENYATSMGSREQLAI 438
+ ++ V GGG E ++ + A +E +A+
Sbjct: 243 QTVKETRTVYGGGCSEMLMAEAVSQLAAKTPGKEAIAM 356
>25854
Length = 800
Score = 57.0 bits (136), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 31/45 (68%), Positives = 35/45 (77%)
Frame = +3
Query: 510 KVKSLKFATEAAITILRIDDLIKLHPESKDDKHGSYEDAVHSGAL 554
KVKSLKFATEAAITILRIDD+IKL + + K SY DAV +G L
Sbjct: 3 KVKSLKFATEAAITILRIDDMIKLVSQEQGGK--SYSDAVRAGEL 131
>17249
Length = 909
Score = 54.7 bits (130), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 33/91 (36%), Positives = 49/91 (53%)
Frame = +3
Query: 441 FARSLLVIPNTLAVNAAQDSTDLVAKLRAFHNEAQVNPERKNLKWIGLDLSNGKPRDNKQ 500
+R+L VI TL N ++ + LRA H + Q N W G+D + G D +
Sbjct: 3 ISRALEVISRTLIQNCGANTIRTLTALRAKHAQGQKNT------W-GIDGNTGNIVDMAE 161
Query: 501 AGVFEPTIVKVKSLKFATEAAITILRIDDLI 531
G++EP VK++ K A E AI +LRIDD++
Sbjct: 162 FGIWEPLSVKLQVYKTACETAILLLRIDDIV 254
>31574
Length = 859
Score = 30.0 bits (66), Expect = 2.7, Method: Compositional matrix adjust.
Identities = 39/148 (26%), Positives = 59/148 (39%), Gaps = 1/148 (0%)
Frame = -3
Query: 53 TITNDGATILK-LLEVEHPAAKVLCELADLQDKEVGDGTTSVVIIAAELLKNADELVKQK 111
T ND A L HP AK +C+LA E+ S + + L K D L+
Sbjct: 857 TFDNDFARALPAYTAFRHPDAKAMCDLAVYNYIEMRSSVNSPLFL---LRKKVDYLL-NA 690
Query: 112 IHPTSVISGYRLACKEAVRYINENLIVNTDELGRDCLINAAKTSMSSKIIGINGDFFANM 171
+ P+ I Y +RY C+ N A KI+ + G M
Sbjct: 689 LFPSLWIPLYTSVSFSRMRY-------------HQCIANRA---WQDKILTMIGWGTTGM 558
Query: 172 VVDAVLAIKYTDIRGQPRYPVNSVNILK 199
+ + A+ YT RGQ VN++++L+
Sbjct: 557 LGACLAALLYTQ-RGQ----VNNISVLE 489
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000295240 | hsapiens_gene_ensembl | Bardet-Biedl
syndrome 5 protein. [Source:Uniprot/SWISSPROT;Acc:Q8N3I7]
(341 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
18333 232 2e-61
17934 160 1e-45
16158 28 3.9
05344 28 3.9
05428 27 8.5
>18333
Length = 411
Score = 232 bits (591), Expect = 2e-61, Method: Compositional matrix adjust.
Identities = 104/135 (77%), Positives = 123/135 (91%)
Frame = -1
Query: 30 LIDCLDSIEDTKGNNGDRGRLLVTNLRILWHSLALSRVNVSVGYNCILNITTRTANSKLR 89
LID LD++EDTKGNNGDRGRL+VTNLRI+WHSLA+ R N+S+G+NC++NI+TRTA S LR
Sbjct: 405 LIDRLDAVEDTKGNNGDRGRLIVTNLRIIWHSLAIPRANLSIGFNCVINISTRTAQSNLR 226
Query: 90 GQTEALYILTKCNSTRFEFIFTNLVPGSPRLFTSVMAVHRAYETSKMYRDFKLRSALIQN 149
G EALY+L KCN+TRFEFIFTNL+PGSPRLFTSV++V RAYETSK+YRD KLR AL+QN
Sbjct: 225 GTVEALYVLCKCNNTRFEFIFTNLIPGSPRLFTSVISVLRAYETSKLYRDLKLRGALVQN 46
Query: 150 KQLRLLPQEHVYDKI 164
KQLRLLPQE VYDK+
Sbjct: 45 KQLRLLPQEQVYDKV 1
Score = 36.2 bits (82), Expect = 0.018, Method: Compositional matrix adjust.
Identities = 17/63 (26%), Positives = 35/63 (55%)
Frame = -1
Query: 162 DKINGVWNLSSDQGNLGTFFITNVRIVWHANMNDSFNVSIPYLQIRSIKIRDSKFGLALV 221
D+++ V + + G+ G +TN+RI+WH+ N+SI + + +I R ++ L
Sbjct: 399 DRLDAVEDTKGNNGDRGRLIVTNLRIIWHSLAIPRANLSIGFNCVINISTRTAQSNLRGT 220
Query: 222 IES 224
+E+
Sbjct: 219 VEA 211
>17934
Length = 1008
Score = 160 bits (405), Expect(2) = 1e-45, Method: Compositional matrix adjust.
Identities = 72/105 (68%), Positives = 89/105 (84%)
Frame = +1
Query: 237 IDPVEKLQESVKEINSLHKVYSASPIFGVDYEMEEKPQPLEALTVEQIQDDVEIDSDGHT 296
DP KLQ+ KEI +LH++YS PIFGV++E E+KPQ +E LT E +QDDVEI++D HT
Sbjct: 88 FDPPGKLQQVAKEIQNLHRIYSTCPIFGVEFETEDKPQSMEELTTEAVQDDVEIENDPHT 267
Query: 297 DAFVAYFADGNKQQDREPVFSEELGLAIEKLKDGFTLQGLWEVMS 341
DAF AYFADGNK++DREPVFSEELGLA+EKLKDGFT+ GLWEV++
Sbjct: 268 DAFAAYFADGNKEKDREPVFSEELGLAVEKLKDGFTIAGLWEVLA 402
Score = 40.4 bits (93), Expect(2) = 1e-45, Method: Compositional matrix adjust.
Identities = 17/24 (70%), Positives = 21/24 (87%)
Frame = +3
Query: 216 FGLALVIESSQQSGGYVLGFKIDP 239
FG+ALV+E+S SGGYVLGF+I P
Sbjct: 24 FGVALVVETSVMSGGYVLGFRIRP 95
>16158
Length = 450
Score = 28.5 bits (62), Expect = 3.9, Method: Compositional matrix adjust.
Identities = 17/68 (25%), Positives = 31/68 (45%), Gaps = 8/68 (11%)
Frame = -1
Query: 74 NCILNITTRTANSKLRGQTEALYILTKCNSTRFEFIFT--------NLVPGSPRLFTSVM 125
NC + TR+ ++ R TKC++ T N +PG+PR+ +++
Sbjct: 288 NCEICGATRSGVTRCR*CVPGTST*TKCSAFSLSVAITSE*KSTDSNFMPGTPRMLSTLQ 109
Query: 126 AVHRAYET 133
+ RAY +
Sbjct: 108 RI*RAYAS 85
>05344
Length = 1178
Score = 28.5 bits (62), Expect = 3.9, Method: Compositional matrix adjust.
Identities = 17/68 (25%), Positives = 31/68 (45%), Gaps = 8/68 (11%)
Frame = +3
Query: 74 NCILNITTRTANSKLRGQTEALYILTKCNSTRFEFIFT--------NLVPGSPRLFTSVM 125
NC + TR+ ++ R TKC++ T N +PG+PR+ +++
Sbjct: 177 NCEICGATRSGVTRCR*CVPGTST*TKCSAFSLSVAITSE*KSTDSNFMPGTPRMLSTLQ 356
Query: 126 AVHRAYET 133
+ RAY +
Sbjct: 357 RI*RAYAS 380
>05428
Length = 782
Score = 27.3 bits (59), Expect = 8.5, Method: Compositional matrix adjust.
Identities = 11/38 (28%), Positives = 23/38 (60%)
Frame = +1
Query: 222 IESSQQSGGYVLGFKIDPVEKLQESVKEINSLHKVYSA 259
++ S Q+ G +K+ ++K+ + K+ +LHKVY+
Sbjct: 595 VKESLQT*GICTSYKLSKLQKILFTYKQTKTLHKVYTV 708
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000257287 | hsapiens_gene_ensembl | Centrosomal
protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).
[Source:Uniprot/SWISSPROT;Acc:Q66GS9]
(1140 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
04618 225 3e-61
16755 44 4e-04
17207 32 1.5
12149 32 1.7
15526 31 2.2
33902 30 4.6
21384 30 7.5
02435 30 7.7
>04618
Length = 1663
Score = 225 bits (574), Expect(2) = 3e-61, Method: Compositional matrix adjust.
Identities = 128/342 (37%), Positives = 212/342 (61%)
Frame = -3
Query: 762 KAVAQMKIMISECESSVNQLKETLVNRDREINSLRRQLDAAHKELDEVGRSREIAFKENR 821
+ V+ +K+ + E ++ ++ + L +DREI SLRRQ+++ +++L E R R+I +ENR
Sbjct: 1661 RVVSDLKVRVGELDAQLHHANDNLCLKDREIKSLRRQVESVNEDLGEASRGRDICVQENR 1482
Query: 822 RLQDDLATMARENQEISLELEAAVQEKEEMKSRVHKYITEVSRWESLMAAKEKENQDLLD 881
RLQDDL A+ENQ+++ EL+ A+ E+E +K +V KYI EV R E ++A KE E DLL+
Sbjct: 1481 RLQDDLTVTAKENQKLNAELQDALAEREALKDQVQKYILEVRRVEDMLANKEAERSDLLE 1302
Query: 882 RFQMLHNRAEDWEVKAHQAEGESSSVRLELLSIDTXXXXXXXXXXXXXKEIQEHINAHHA 941
+++ L AE ++ +HQ E E S++RLE+++ ++ +EIQEH+ + A
Sbjct: 1301 QYRKLSLEAEQFQTTSHQLESEGSNMRLEIMTKESELRRAHDKLDNLEREIQEHVQSQQA 1122
Query: 942 YESQISSMAKAMSRLEEELRHQEDEKATVLNDLSSLRELCIKLDSGKDIMTQQLNSKNLE 1001
YE Q+ S+ ++++ LEE LR EDEK+ + D +S RE +LD K+ + ++L + LE
Sbjct: 1121 YEQQVVSLTRSVTTLEESLRQAEDEKSVLRADYTSSRESATQLDGQKEQLQRRLAALQLE 942
Query: 1002 FERVVVELENVKSESDLLKKQLSNERHTVKNLESLLATNRDKEFHSHLTSHEKDTEIXXX 1061
E++ +E+++ ES+ L+ Q+S ER TVKNLE+LL R+KEF + L+S E++TEI
Sbjct: 941 KEQLHSLVEDLRQESECLQDQVSQERSTVKNLEALLQNGREKEFQNQLSSQERNTEIQML 762
Query: 1062 XXXXXXXXXXXXXXXRENTMLRAKVAQLQTDYDALKRQISTE 1103
RE R + +L+ D + L+RQ++ E
Sbjct: 761 KDRLSLNESKLQSQAREVASFRTRNVELEGDIERLRRQLTNE 636
Score = 29.6 bits (65), Expect(2) = 3e-61, Method: Compositional matrix adjust.
Identities = 11/16 (68%), Positives = 16/16 (100%)
Frame = -2
Query: 1104 RYERERAIQEMRRHGL 1119
R+ERERA+QE+RR+G+
Sbjct: 636 RFERERAVQELRRNGI 589
>16755
Length = 426
Score = 43.9 bits (102), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 31/96 (32%), Positives = 60/96 (62%), Gaps = 4/96 (4%)
Frame = +3
Query: 316 CQELTEIDQLAQQLERHKEEVLETADKELGEAKKEIKRKLSEMQDLEETMAKLQLELNLC 375
CQ L +D++A +L+ K+ V+ AD+E+GEAK E+++ E++DL+ +++L+ E
Sbjct: 93 CQ-LQNVDRVAAKLQTDKDVVVRAADREMGEAKTELEKSRHELEDLDNLVSQLRAENKRM 269
Query: 376 QKEKERLSDELLVKS----DLETVVHQLEQEKQRLS 407
+K+ + L V+ LE ++ + ++EK+RLS
Sbjct: 270 EKDFSDMKARLAVREADNRKLEDLLDRXQEEKKRLS 377
>17207
Length = 567
Score = 32.0 bits (71), Expect = 1.5, Method: Compositional matrix adjust.
Identities = 16/35 (45%), Positives = 22/35 (62%)
Frame = +3
Query: 606 LEKTIEHLTCVNHQLESEKYELKSKVLIMKETIES 640
L+K +HL VN + + + L+SKVL KE IES
Sbjct: 246 LQKNYDHLFAVNEKAKGGSFYLQSKVLRAKERIES 350
>12149
Length = 576
Score = 31.6 bits (70), Expect = 1.7, Method: Compositional matrix adjust.
Identities = 16/35 (45%), Positives = 22/35 (62%)
Frame = +3
Query: 606 LEKTIEHLTCVNHQLESEKYELKSKVLIMKETIES 640
L+K +HL VN + + + L+SKVL KE IES
Sbjct: 252 LQKNYDHLFAVNEKAKGGSFYLQSKVLRAKERIES 356
>15526
Length = 869
Score = 31.2 bits (69), Expect = 2.2, Method: Compositional matrix adjust.
Identities = 16/35 (45%), Positives = 22/35 (62%)
Frame = +3
Query: 606 LEKTIEHLTCVNHQLESEKYELKSKVLIMKETIES 640
L+K +HL VN + + + L+SKVL KE IES
Sbjct: 546 LQKNYDHLFAVNEKAKGGSFYLQSKVLRAKERIES 650
>33902
Length = 671
Score = 30.4 bits (67), Expect = 4.6, Method: Compositional matrix adjust.
Identities = 28/78 (35%), Positives = 45/78 (57%), Gaps = 4/78 (5%)
Frame = -2
Query: 575 LSDLRRIMA---EKEALREKLE-HIEEVSLFGKSELEKTIEHLTCVNHQLESEKYELKSK 630
L+ R++MA EK AL KLE H++ V+ K+ +KT+ +CV E+YE +
Sbjct: 385 LASERKMMAQLEEKSALILKLEEHLKSVTAENKALRDKTVSMTSCV------EEYEKTME 224
Query: 631 VLIMKETIESLENKLKVQ 648
VLI+ + S E+K ++Q
Sbjct: 223 VLIVAKEKSSSESKAQIQ 170
>21384
Length = 684
Score = 29.6 bits (65), Expect = 7.5, Method: Compositional matrix adjust.
Identities = 25/64 (39%), Positives = 34/64 (53%)
Frame = +1
Query: 739 LQETVDEKTEKIANLQENLANKEKAVAQMKIMISECESSVNQLKETLVNRDREINSLRRQ 798
LQE + + E+IA L EK V + +S+CE+ QL+E R E+NSLR Q
Sbjct: 454 LQEDGNRRCEEIARL-------EKEVWRKSATVSQCEA---QLEE----RGDEVNSLRSQ 591
Query: 799 LDAA 802
L A
Sbjct: 592 LTQA 603
>02435
Length = 1890
Score = 29.6 bits (65), Expect = 7.7, Method: Compositional matrix adjust.
Identities = 46/177 (25%), Positives = 82/177 (46%), Gaps = 3/177 (1%)
Frame = +2
Query: 319 LTEIDQLAQQLERHKEEVLETADKELGEAKKEIKRKLSEMQDLEETMAKLQLELNLCQKE 378
TEI+ AQQ ++ +EE + ++ + EAK + E QD + MA ++L +
Sbjct: 1001 FTEIENRAQQADKEREEFAK--NQAIQEAKTQ------EEQDKQ--MASMRLAYQDMSVQ 1150
Query: 379 KERLSDELLVKSDLETVVHQLEQEKQRL--SKKVESFAVTERQLTLEVERMRLEHGIKRR 436
+++ D++ SD + QLE+ +K + AV++ Q T++ E R
Sbjct: 1151 RKKQEDKIKA-SDPKKAA-QLERLGMGFISNKGISHSAVSDMQ-TIQQE-------APSR 1300
Query: 437 DRSPSRLDTFLKGIEEERDYYKKELERLQHIIQRRSCS-TSYSAREKSSIFRTPEKG 492
R+ R D F G +RD+++ EL+ L +R +S +R + P KG
Sbjct: 1301 SRNSDR-DLFSSGRNRDRDFFEDELDSLSGFSSKRGGGDSSRGSRVDDFGWGNPNKG 1468
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000376431 | hsapiens_gene_ensembl | Bardet-Biedl
syndrome 5 protein. [Source:Uniprot/SWISSPROT;Acc:Q8N3I7]
(320 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
18333 231 3e-61
17934 160 2e-41
16158 28 3.6
05344 28 3.6
>18333
Length = 411
Score = 231 bits (590), Expect = 3e-61, Method: Compositional matrix adjust.
Identities = 104/135 (77%), Positives = 123/135 (91%)
Frame = -1
Query: 30 LIDCLDSIEDTKGNNGDRGRLLVTNLRILWHSLALSRVNVSVGYNCILNITTRTANSKLR 89
LID LD++EDTKGNNGDRGRL+VTNLRI+WHSLA+ R N+S+G+NC++NI+TRTA S LR
Sbjct: 405 LIDRLDAVEDTKGNNGDRGRLIVTNLRIIWHSLAIPRANLSIGFNCVINISTRTAQSNLR 226
Query: 90 GQTEALYILTKCNSTRFEFIFTNLVPGSPRLFTSVMAVHRAYETSKMYRDFKLRSALIQN 149
G EALY+L KCN+TRFEFIFTNL+PGSPRLFTSV++V RAYETSK+YRD KLR AL+QN
Sbjct: 225 GTVEALYVLCKCNNTRFEFIFTNLIPGSPRLFTSVISVLRAYETSKLYRDLKLRGALVQN 46
Query: 150 KQLRLLPQEHVYDKI 164
KQLRLLPQE VYDK+
Sbjct: 45 KQLRLLPQEQVYDKV 1
Score = 34.3 bits (77), Expect = 0.062, Method: Compositional matrix adjust.
Identities = 15/50 (30%), Positives = 27/50 (54%), Gaps = 6/50 (12%)
Frame = -1
Query: 158 EHVYDKINGVWNLSSDQGNLGTFFITNVRIVWH------ANMNDSFNVSI 201
+ D+++ V + + G+ G +TN+RI+WH AN++ FN I
Sbjct: 411 RKLIDRLDAVEDTKGNNGDRGRLIVTNLRIIWHSLAIPRANLSIGFNCVI 262
>17934
Length = 1008
Score = 160 bits (404), Expect(2) = 2e-41, Method: Compositional matrix adjust.
Identities = 72/105 (68%), Positives = 89/105 (84%)
Frame = +1
Query: 216 IDPVEKLQESVKEINSLHKVYSASPIFGVDYEMEEKPQPLEALTVEQIQDDVEIDSDGHT 275
DP KLQ+ KEI +LH++YS PIFGV++E E+KPQ +E LT E +QDDVEI++D HT
Sbjct: 88 FDPPGKLQQVAKEIQNLHRIYSTCPIFGVEFETEDKPQSMEELTTEAVQDDVEIENDPHT 267
Query: 276 DAFVAYFADGNKQQDREPVFSEELGLAIEKLKDGFTLQGLWEVMS 320
DAF AYFADGNK++DREPVFSEELGLA+EKLKDGFT+ GLWEV++
Sbjct: 268 DAFAAYFADGNKEKDREPVFSEELGLAVEKLKDGFTIAGLWEVLA 402
Score = 26.6 bits (57), Expect(2) = 2e-41, Method: Compositional matrix adjust.
Identities = 10/13 (76%), Positives = 12/13 (92%)
Frame = +3
Query: 206 ISGGYVLGFKIDP 218
+SGGYVLGF+I P
Sbjct: 57 MSGGYVLGFRIRP 95
>16158
Length = 450
Score = 28.5 bits (62), Expect = 3.6, Method: Compositional matrix adjust.
Identities = 17/68 (25%), Positives = 31/68 (45%), Gaps = 8/68 (11%)
Frame = -1
Query: 74 NCILNITTRTANSKLRGQTEALYILTKCNSTRFEFIFT--------NLVPGSPRLFTSVM 125
NC + TR+ ++ R TKC++ T N +PG+PR+ +++
Sbjct: 288 NCEICGATRSGVTRCR*CVPGTST*TKCSAFSLSVAITSE*KSTDSNFMPGTPRMLSTLQ 109
Query: 126 AVHRAYET 133
+ RAY +
Sbjct: 108 RI*RAYAS 85
>05344
Length = 1178
Score = 28.5 bits (62), Expect = 3.6, Method: Compositional matrix adjust.
Identities = 17/68 (25%), Positives = 31/68 (45%), Gaps = 8/68 (11%)
Frame = +3
Query: 74 NCILNITTRTANSKLRGQTEALYILTKCNSTRFEFIFT--------NLVPGSPRLFTSVM 125
NC + TR+ ++ R TKC++ T N +PG+PR+ +++
Sbjct: 177 NCEICGATRSGVTRCR*CVPGTST*TKCSAFSLSVAITSE*KSTDSNFMPGTPRMLSTLQ 356
Query: 126 AVHRAYET 133
+ RAY +
Sbjct: 357 RI*RAYAS 380
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000306124 | hsapiens_gene_ensembl | Protein kinase
C epsilon type (EC 2.7.11.13) (nPKC-epsilon).
[Source:Uniprot/SWISSPROT;Acc:Q02156]
(737 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
18484 219 7e-61
30755 206 2e-53
03240 163 2e-40
18663 149 4e-36
26156 117 2e-32
00486 134 2e-31
25019 83 5e-27
12721 118 8e-27
31885 110 2e-24
14420 108 8e-24
18921 103 2e-22
27405 101 1e-21
01707 100 2e-21
09606 99 7e-21
15910 96 4e-20
00300 94 2e-19
13066 92 1e-18
26560 90 4e-18
13592 89 5e-18
14126 83 5e-16
25445 82 6e-16
06405 82 8e-16
17722 82 9e-16
01060 80 4e-15
13212 78 1e-14
19094 75 1e-13
21079 73 4e-13
21433 72 6e-13
27546 71 2e-12
01756 70 4e-12
04591 70 4e-12
28638 53 4e-12
00392 68 1e-11
29581 68 1e-11
35187 68 2e-11
01392 67 2e-11
32957 65 8e-11
11185 64 2e-10
09007 64 2e-10
21808 63 5e-10
16708 62 1e-09
26711 62 1e-09
38560 62 1e-09
12786 60 3e-09
01966 59 7e-09
04852 59 7e-09
14116 58 1e-08
19761 58 2e-08
11353 57 2e-08
03508 57 3e-08
17975 56 4e-08
03942 56 4e-08
37602 56 4e-08
11780 52 4e-08
17300 56 5e-08
04138 55 9e-08
00715 54 2e-07
30339 54 3e-07
22804 54 3e-07
07940 53 5e-07
32000 51 1e-06
19361 51 2e-06
12672 50 3e-06
12442 50 4e-06
19301 49 1e-05
01718 48 1e-05
29590 45 8e-05
07291 45 8e-05
07836 45 8e-05
20152 45 9e-05
27274 45 1e-04
17932 33 2e-04
11404 44 3e-04
33586 44 3e-04
17253 42 8e-04
18481 42 8e-04
14477 41 0.001
18401 40 0.005
30743 39 0.005
02638 39 0.007
18996 39 0.009
17516 37 0.022
26009 35 0.092
31120 35 0.16
00638 34 0.17
26052 34 0.18
02913 34 0.18
23319 33 0.57
31489 31 1.6
15549 31 1.9
36643 31 2.2
37063 30 3.5
36481 30 3.7
17637 29 8.2
>18484
Length = 635
Score = 219 bits (559), Expect(2) = 7e-61, Method: Compositional matrix adjust.
Identities = 99/160 (61%), Positives = 123/160 (76%)
Frame = +1
Query: 493 DLMFQIQRSRKFDEPRSRFYAAEVTSALMFLHQHGVIYRDLKLDNILLDAEGHCKLADFG 552
DLM++IQ+ KF EP + FYAAE+ L FLH G+IYRDLKLDN++LD+EGH K+ADFG
Sbjct: 1 DLMYRIQQEGKFKEPVAAFYAAEIAVGLFFLHDQGIIYRDLKLDNVMLDSEGHIKIADFG 180
Query: 553 MCKEGILNGVTTTTFCGTPDYIAPEILQELEYGPSVDWWALGVLMYEMMAGQPPFEADNE 612
MCKEG+ TT TFCGTPDYIAPEI+ Y SVDWWA GVL++EM+AGQPPF+ ++E
Sbjct: 181 MCKEGMTGDATTRTFCGTPDYIAPEIVLYQPYSKSVDWWAYGVLLFEMLAGQPPFDGEDE 360
Query: 613 DDLFESILHDDVLYPVWLSKEAVSILKAFMTKNPHKRLGC 652
D+LF SI +V YP +S+EAVS+ K + KNP KRLGC
Sbjct: 361 DELFSSITDHNVSYPKAMSREAVSLCKGLLMKNPTKRLGC 480
Score = 33.5 bits (75), Expect(2) = 7e-61, Method: Compositional matrix adjust.
Identities = 19/55 (34%), Positives = 24/55 (43%)
Frame = +2
Query: 650 LGCVASQNGEDAIKQHPFFKEIDWVLLEQXXXXXXXXXXXXXXXDVNNFDQDFTR 704
LG V QNGE I+ H FF+ I W ++ NFD+ FTR
Sbjct: 473 LGVV--QNGERDIRDHAFFRRIVWDKIKSMEVQPPYKPKITDRRKAENFDKSFTR 631
>30755
Length = 1137
Score = 206 bits (525), Expect = 2e-53, Method: Compositional matrix adjust.
Identities = 109/239 (45%), Positives = 144/239 (60%), Gaps = 2/239 (0%)
Frame = +2
Query: 497 QIQRSRKFDEPRSRFYAAEVTSALMFLHQHGVIYRDLKLDNILLDAEGHCKLADFGMCKE 556
+ R F E R+RFY AE+ SAL +LH G+IYRDLKL+N+LLD +GH K+ADFG+CKE
Sbjct: 2 HLSHERIFTEERTRFYGAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCKE 181
Query: 557 GILNGVTTTTFCGTPDYIAPEILQELEYGPSVDWWALGVLMYEMMAGQPPFEADNEDDLF 616
I G TT TFCGTP+Y+APE+L + +YG +VDWW GV+MYEM+ G+ PF + D LF
Sbjct: 182 DITYGRTTKTFCGTPEYLAPEVLDDNDYGRAVDWWGTGVVMYEMICGRLPFYNRDHDVLF 361
Query: 617 ESILHDDVLYPVWLSKEAVSILKAFMTKNPHKRLGCVASQNGEDAIKQHPFFKEIDWVLL 676
IL +DV +P ++ EA S+L + K+P RLG Q+ I+ HPFF I+W L
Sbjct: 362 TLILVEDVKFPRNITDEAKSLLSGLLAKDPRNRLG--GGQDDVKEIQAHPFFASINWTDL 535
Query: 677 EQXXXXXXXXXXXXXXXDVNNFDQDFTREEPVLTLVD-EAIVKQINQEE-FKGFSYFGE 733
Q D FD++FT E LT D + I +E F FSY G+
Sbjct: 536 VQKKITPPFKPQVTSDTDTRYFDEEFTGESVELTPPDPTGPLXSIAEEPLFPQFSYQGD 712
>03240
Length = 1683
Score = 163 bits (413), Expect = 2e-40, Method: Compositional matrix adjust.
Identities = 112/333 (33%), Positives = 162/333 (48%), Gaps = 55/333 (16%)
Frame = -3
Query: 401 KRLGLDE--FNFIKVLGKGSFGKVMLAELKGKDEVYAVKVLKKDVILQDDDVDCTMTEKR 458
KR +D+ F IK LG G+FG+V L +YA+K L+K +L+ + V E+
Sbjct: 1312 KRAKMDKCMFEKIKTLGVGAFGEVSLCRKNDTGMLYAMKTLRKSDVLKRNQVAHVKAERD 1133
Query: 459 ILALARKHPYLTQLYCCFQTKDRLFFVMEYVNGGDLMFQIQRSRKFDEPRSRFYAAEVTS 518
ILA A + ++ +LY FQ + L+FVM+YV GGDLM + R DEP +RFY AE+
Sbjct: 1132 ILAEA-DNEWVVKLYYSFQDHNYLYFVMDYVPGGDLMGLLIRMEILDEPLARFYVAELVQ 956
Query: 519 ALMFLHQHGVIYRDLKLDNILLDAEGHCKLADFGMC-------------KEG-------- 557
A+ +H+ G I+RD+K DNIL+D GH KL DFG+C ++G
Sbjct: 955 AIESVHRMGFIHRDIKPDNILIDRNGHIKLTDFGLCTGFRWTHNSKYYQRDGTHARQDSM 776
Query: 558 -------------ILNGVT----------TTTFCGTPDYIAPEILQEL-EYGPSVDWWAL 593
IL + + GTP+YIAPE+L L Y DWW++
Sbjct: 775 EVKCQLDEQCQCEILKPLERRRKREQRCLAHSLVGTPNYIAPEVLSRLGGYTSVCDWWSV 596
Query: 594 GVLMYEMMAGQPPFEADNEDDLFESILHDDVLYPVWLSKEAVSILKAFMTKNPHK----R 649
GV+++EM+ G PPF A+ + Y V K+ + I + P K R
Sbjct: 595 GVILFEMLVGHPPFYANTP---------AETQYKVINWKDMLKIPRESNLSQPAKDLILR 443
Query: 650 LGCVASQ----NGEDAIKQHPFFKEIDWVLLEQ 678
L C + NG IK H FF +++ L +
Sbjct: 442 LCCGSDDRLGLNGAGEIKTHMFFAGVNFETLRK 344
>18663
Length = 600
Score = 149 bits (376), Expect = 4e-36, Method: Compositional matrix adjust.
Identities = 83/181 (45%), Positives = 106/181 (58%), Gaps = 9/181 (4%)
Frame = +2
Query: 565 TTFCGTPDYIAPEILQELEYGPSVDWWALGVLMYEMMAGQPPFEA---------DNEDDL 615
+TFCGTP+YIAPEIL+ +YG SVDWWALGVL+YEM+AG+ PF+ + ED L
Sbjct: 2 STFCGTPNYIAPEILRGEDYGFSVDWWALGVLLYEMLAGRSPFDIAGASENPDQNTEDYL 181
Query: 616 FESILHDDVLYPVWLSKEAVSILKAFMTKNPHKRLGCVASQNGEDAIKQHPFFKEIDWVL 675
F+ IL + P LS +A S+LK F+ KNP RLGC D I HPFFK IDW +
Sbjct: 182 FQVILEKTIRIPRSLSVKAASVLKGFLNKNPADRLGCHRESAFMD-IVNHPFFKVIDWEM 358
Query: 676 LEQXXXXXXXXXXXXXXXDVNNFDQDFTREEPVLTLVDEAIVKQINQEEFKGFSYFGEDL 735
LE+ D+ NF +FT E LT D+ ++ I+Q EF+GF Y L
Sbjct: 359 LERKQVSPPFKPRLDSDRDLANFPIEFTGEPVQLTPDDDHVIDSIDQSEFEGFEYVNPLL 538
Query: 736 M 736
M
Sbjct: 539 M 541
>26156
Length = 479
Score = 117 bits (292), Expect(2) = 2e-32, Method: Compositional matrix adjust.
Identities = 51/110 (46%), Positives = 78/110 (70%)
Frame = -1
Query: 402 RLGLDEFNFIKVLGKGSFGKVMLAELKGKDEVYAVKVLKKDVILQDDDVDCTMTEKRILA 461
+LGL +F ++V+G+GS+ KV+ E K +YA+KV+KK+++ D+D+D TEK +
Sbjct: 401 KLGLTDFLLLRVIGRGSYAKVLQVEHKRTKRIYAMKVIKKELVNDDEDIDWVQTEKHVFE 222
Query: 462 LARKHPYLTQLYCCFQTKDRLFFVMEYVNGGDLMFQIQRSRKFDEPRSRF 511
A +P+L L+ CFQ++ RLFFV+E+VNGGDLMF +QR R+ E +RF
Sbjct: 221 TATNYPFLVGLHSCFQSESRLFFVIEFVNGGDLMFHMQRQRRLPEEHARF 72
Score = 40.8 bits (94), Expect(2) = 2e-32, Method: Composition-based stats.
Identities = 16/25 (64%), Positives = 21/25 (84%)
Frame = -3
Query: 511 FYAAEVTSALMFLHQHGVIYRDLKL 535
FY+AE+ AL FLH+ G++YRDLKL
Sbjct: 75 FYSAEICLALNFLHKRGIVYRDLKL 1
>00486
Length = 797
Score = 134 bits (336), Expect = 2e-31, Method: Compositional matrix adjust.
Identities = 68/173 (39%), Positives = 94/173 (54%)
Frame = -2
Query: 564 TTTFCGTPDYIAPEILQELEYGPSVDWWALGVLMYEMMAGQPPFEADNEDDLFESILHDD 623
T TFCGT +Y+APEIL +G +VDWW+LG LMY+M+ G PPF A+N + IL
Sbjct: 787 THTFCGTIEYMAPEILTRTGHGKAVDWWSLGALMYDMLTGSPPFTAENRKKTIDKILKGK 608
Query: 624 VLYPVWLSKEAVSILKAFMTKNPHKRLGCVASQNGEDAIKQHPFFKEIDWVLLEQXXXXX 683
+ P +L+ EA ++K + KNP +RLG +G IK H FF+ +W LL
Sbjct: 607 LNLPPYLTNEARGLIKKLLRKNPAERLGGGHDDSG--PIKDHQFFRNTNWALLALRRAEP 434
Query: 684 XXXXXXXXXXDVNNFDQDFTREEPVLTLVDEAIVKQINQEEFKGFSYFGEDLM 736
D + FD FTR+ PV + D + INQ FKGF+Y ++
Sbjct: 433 PFRPNVTSDEDTSQFDTKFTRQTPVDSPDDTILSDSINQ-VFKGFTYIAPSVL 278
>25019
Length = 730
Score = 83.2 bits (204), Expect(2) = 5e-27, Method: Composition-based stats.
Identities = 34/59 (57%), Positives = 43/59 (72%)
Frame = +3
Query: 536 DNILLDAEGHCKLADFGMCKEGILNGVTTTTFCGTPDYIAPEILQELEYGPSVDWWALG 594
+N+LLD +GH KL DFG+CKE I T TFCGT +Y+APEIL +G +VDWW+LG
Sbjct: 261 ENVLLDKDGHVKLTDFGLCKEAITGTRVTHTFCGTIEYMAPEILTRTGHGKAVDWWSLG 437
Score = 56.6 bits (135), Expect(2) = 5e-27, Method: Composition-based stats.
Identities = 24/58 (41%), Positives = 35/58 (60%)
Frame = +1
Query: 594 GVLMYEMMAGQPPFEADNEDDLFESILHDDVLYPVWLSKEAVSILKAFMTKNPHKRLG 651
G LMY+M+ G PPF A+N + IL + P +L+ EA ++K + KNP +RLG
Sbjct: 436 GALMYDMLTGSPPFTAENRKKTIDKILKGKLNLPPYLTNEARGLIKKLLRKNPAERLG 609
>12721
Length = 821
Score = 118 bits (296), Expect = 8e-27, Method: Compositional matrix adjust.
Identities = 71/206 (34%), Positives = 111/206 (53%)
Frame = +1
Query: 402 RLGLDEFNFIKVLGKGSFGKVMLAELKGKDEVYAVKVLKKDVILQDDDVDCTMTEKRILA 461
R LD+F I G+GS G V +A + ++ AVK + L+ + + ++
Sbjct: 85 RTFLDDFMKI---GEGSTGIVCIATSRDGRQM-AVKKMD----LRKQQRRELLFNEVVVM 240
Query: 462 LARKHPYLTQLYCCFQTKDRLFFVMEYVNGGDLMFQIQRSRKFDEPRSRFYAAEVTSALM 521
HP + ++Y + D L+ VME++ GG L I + + DE + AL
Sbjct: 241 RDYHHPNIVEMYNSYLVNDELWVVMEFMEGGALT-DIVTNNRMDEVQIATVCRACLKALA 417
Query: 522 FLHQHGVIYRDLKLDNILLDAEGHCKLADFGMCKEGILNGVTTTTFCGTPDYIAPEILQE 581
FLH +GVI+RD+K D+ILL +G KL DFG C + + + GTP ++APE++
Sbjct: 418 FLHANGVIHRDIKSDSILLSHDGKVKLXDFGFCAQVTQDLQKRKSLVGTPYWMAPEVISR 597
Query: 582 LEYGPSVDWWALGVLMYEMMAGQPPF 607
L YGP VD W+LG+++ EM+ +PPF
Sbjct: 598 LPYGPEVDIWSLGIMVMEMIDAEPPF 675
>31885
Length = 529
Score = 110 bits (275), Expect = 2e-24, Method: Compositional matrix adjust.
Identities = 56/157 (35%), Positives = 90/157 (57%), Gaps = 5/157 (3%)
Frame = -2
Query: 466 HPYLTQLYCCFQTKDRLFFVMEYVNGGDLMFQIQRSRKFDEPRSRFYAAEVTSALMFLHQ 525
HP+L L+ FQ ++ LF V++ GGDL + +Q+ F E +FY ++ L +L
Sbjct: 495 HPFLVNLWYAFQDEEDLFMVVDLFLGGDLRYHMQQEVSFREDCVKFYLCQLALVLDYLRS 316
Query: 526 HGVIYRDLKLDNILLDAEGHCKLADFGMCKEGILNGVTTTTFCGTPDYIAPEIL-----Q 580
+++RD+K DNILLD +GHC + DF + + + + T+T GT Y+APE+ +
Sbjct: 315 QKIVHRDIKPDNILLDEQGHCHVTDFNIATQLEDDELATST-SGTRPYMAPEVYGVAINE 139
Query: 581 ELEYGPSVDWWALGVLMYEMMAGQPPFEADNEDDLFE 617
YG VDWW+LGV ++E++ + PF + L E
Sbjct: 138 RRGYGFPVDWWSLGVSLFELLKKRRPFSVHSNTSLHE 28
>14420
Length = 528
Score = 108 bits (270), Expect = 8e-24, Method: Compositional matrix adjust.
Identities = 55/147 (37%), Positives = 84/147 (57%)
Frame = +2
Query: 465 KHPYLTQLYCCFQTKDRLFFVMEYVNGGDLMFQIQRSRKFDEPRSRFYAAEVTSALMFLH 524
++P + + + L+ VME++ GG L + DE + E AL FLH
Sbjct: 74 QNPNIVNYLDSYLVGEELWVVMEFLAGGSLT-DVVTETCMDEGQIAAVCRECLQALEFLH 250
Query: 525 QHGVIYRDLKLDNILLDAEGHCKLADFGMCKEGILNGVTTTTFCGTPDYIAPEILQELEY 584
++ VI+RD+K DNILL +G KL DFG C + +T GTP ++APE++ +Y
Sbjct: 251 ENQVIHRDIKSDNILLGMDGSVKLTDFGFCAQLSPEQSKRSTMVGTPYWMAPEVVTRKQY 430
Query: 585 GPSVDWWALGVLMYEMMAGQPPFEADN 611
GP+VD W+LGV+ EM+ G+PP+ +N
Sbjct: 431 GPTVDIWSLGVMCIEMIEGEPPYLNEN 511
>18921
Length = 697
Score = 103 bits (258), Expect = 2e-22, Method: Compositional matrix adjust.
Identities = 64/202 (31%), Positives = 101/202 (50%), Gaps = 1/202 (0%)
Frame = +2
Query: 406 DEFNFIKVLGKGSFGKVMLAELKGKDEVYAVKVLKKDVILQDDDVDCTMTEKRILALARK 465
D F+ + LG+GS+G V + K +V A+K + D LQ+ + ++ ++
Sbjct: 29 DVFDILGKLGEGSYGSVFKSLHKETGQVLAIKQVPVDTDLQEIIKEISIMQQC------D 190
Query: 466 HPYLTQLYCCFQTKDRLFFVMEYVNGGDLMFQIQ-RSRKFDEPRSRFYAAEVTSALMFLH 524
Y+ + Y + L+ VMEY G + ++ R++ E L +LH
Sbjct: 191 SKYIVKYYGSYFKNTDLWIVMEYCGAGSVSDIMRLRNKTLVEREIATILYYTLKGLXYLH 370
Query: 525 QHGVIYRDLKLDNILLDAEGHCKLADFGMCKEGILNGVTTTTFCGTPDYIAPEILQELEY 584
I+RD+K NILL+ EGH KLADFG+ + T GTP ++APE++QE+ Y
Sbjct: 371 SRRKIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTPYWMAPEVIQEIGY 550
Query: 585 GPSVDWWALGVLMYEMMAGQPP 606
D W+LG+ EM G+PP
Sbjct: 551 DCVADIWSLGITALEMAEGKPP 616
>27405
Length = 532
Score = 101 bits (251), Expect = 1e-21, Method: Compositional matrix adjust.
Identities = 60/178 (33%), Positives = 93/178 (52%), Gaps = 4/178 (2%)
Frame = -3
Query: 418 SFGKVMLAELKGKDEVYAVKVLKKDVILQDDDVDCTMTEKRILALARK---HPYLTQLYC 474
FG+V ++YA+K L K I + E+ +L+L P++ +
Sbjct: 530 GFGEVYGCRKADTGKMYAMKCLDKKRIKMKGGETLALNERIMLSLVSTGEGSPFIVCMTY 351
Query: 475 CFQTKDRLFFVMEYVNGGDLMFQIQRSRKFDEPRSRFYAAEVTSALMFLHQHGVIYRDLK 534
FQT ++L F+++ +NGGDL + + + F E RFYAAEV L +H V+YRDLK
Sbjct: 350 AFQTPEKLCFILDLMNGGDLHYHLSQHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLK 171
Query: 535 LDNILLDAEGHCKLADFGMCKEGILNGVTTTTFCGTPDYIAPEILQELE-YGPSVDWW 591
NILLD GH +++D G+ + + GT Y+APE+L + + Y S DW+
Sbjct: 170 PANILLDENGHVRISDLGLACD--FSKKKPHASVGTHGYMAPEVLMKGQAYDSSADWF 3
>01707
Length = 757
Score = 100 bits (248), Expect = 2e-21, Method: Compositional matrix adjust.
Identities = 69/217 (31%), Positives = 110/217 (50%), Gaps = 2/217 (0%)
Frame = +1
Query: 405 LDEFNFIKVLGKGSFGKVMLAELKGKDEVYAVKVLKKDVILQDDDVDCTMTEKRILALAR 464
++++ I +G+GS+G V K ++ A+K K V +DD + + + I L +
Sbjct: 61 MEKYEKIGKIGEGSYGVVFKCRNKETSQLVAIK---KFVESEDDPLIKKIAMREIRMLKQ 231
Query: 465 -KHPYLTQLYCCFQTKDRLFFVMEYVNGGDLMFQIQRSRKFDEPRSRFYAAEVTSALMFL 523
KHP L +L F+ K RL V +YV+ L + R EP + + A+ F
Sbjct: 232 LKHPNLVRLIEVFRRKKRLHLVFDYVDHTLLNELDRYPRGLPEPMVKRIIYQTLLAVNFC 411
Query: 524 HQHGVIYRDLKLDNILLDAEGHCKLADFGMCKEGILNGVTTTTFCGTPDYIAPEIL-QEL 582
HQ+ I+RD+K +NIL+ +G KL DFG + G T + T Y APE+L +
Sbjct: 412 HQYNTIHRDVKPENILITRQGQVKLCDFGFARILTGPGDEYTDYVATRWYRAPELLVGDT 591
Query: 583 EYGPSVDWWALGVLMYEMMAGQPPFEADNEDDLFESI 619
+YGP VD WA+G + E++ GQ + ++ D I
Sbjct: 592 QYGPPVDVWAIGCVFAELLTGQALWPGRSDVDQLHLI 702
>09606
Length = 1300
Score = 98.6 bits (244), Expect = 7e-21, Method: Compositional matrix adjust.
Identities = 70/283 (24%), Positives = 124/283 (43%), Gaps = 33/283 (11%)
Frame = -3
Query: 405 LDEFNFIKVLGKGSFGKVMLAELKGKDEVYAVKVLKKDVILQDDDVDCTMTEKRILALAR 464
++ F + LGKG + KG A+ ++K + +V T+ ++
Sbjct: 1118 MENFVLYEELGKGEHSIIYKGRRKGTINFVAIHCIEK---CKRPEVTNTVRMTHDIS--- 957
Query: 465 KHPYLTQLYCCFQTKDRLFFVMEYVNGGDLMFQIQRSRKFDEPRSRFYAAEVTSALMFLH 524
HP + Q + ++T + L+ V+E GG L + + E R + + + L ++H
Sbjct: 956 -HPNVVQFHEWYETSNHLWLVVELCTGGSLADILAQDHHLPETSIRDFGIHLVTGLHYIH 780
Query: 525 QHGVIYRDLKLDNILLDAEGHCKLADFGMCK-------------------------EGIL 559
G+++ DL+ +LLD G K ADFG+ K E ++
Sbjct: 779 SLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQWNIQSAEEMM 600
Query: 560 NGVTTTTFCGTPDYIAPEILQELEYGPSVDWWALGVLMYEMMAGQPPFEADNEDDLFESI 619
V T+ G+P Y+APE+ Q E D WALG + YEM +G PPF + D + +
Sbjct: 599 KQVPTS---GSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSGHPPFLGETYDITKDKV 429
Query: 620 LHDDVLYP--------VWLSKEAVSILKAFMTKNPHKRLGCVA 654
L+ + P S E +++L++ + K+ +RL +
Sbjct: 428 LNKEFPLPKVKGSRLSAKPSPEFLNLLESLLQKDSTRRLSWAS 300
>15910
Length = 1361
Score = 96.3 bits (238), Expect = 4e-20, Method: Compositional matrix adjust.
Identities = 50/144 (34%), Positives = 88/144 (61%), Gaps = 7/144 (4%)
Frame = +2
Query: 514 AEVTSALMFLHQHGVIYRDLKLDNILLDA---EGHCKLADFGMCKEGILNGVTTTTFCGT 570
+++ + ++H +GV++RDLK +N+L + + KLADFG+ + I V +T CGT
Sbjct: 485 SDILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLADFGLSR-IIEPEVQMSTVCGT 661
Query: 571 PDYIAPEILQELEYGPSVDWWALGVLMYEMMAGQPPFEADNEDDLFESILHDDVLY--PV 628
P Y APE+L+ +Y PSVD W++GV+ Y ++ G PF A+NE +++ I+ + +
Sbjct: 662 PGYCAPEVLKGDKYTPSVDMWSVGVIAYILLCGYEPFFAENEFEMYRKIIKGEYKFDEEY 841
Query: 629 W--LSKEAVSILKAFMTKNPHKRL 650
W +S+ A +++ + +P KRL
Sbjct: 842 WSEISENAKDVVRKLLVIDPKKRL 913
>00300
Length = 2318
Score = 94.0 bits (232), Expect = 2e-19, Method: Compositional matrix adjust.
Identities = 75/256 (29%), Positives = 120/256 (46%), Gaps = 13/256 (5%)
Frame = -1
Query: 414 LGKGSFGKVMLAELKGKDEVYAVKVLKKDVILQDDDVDC--TMTEKRILALARKHPYLTQ 471
+G+G FGKV A E+ A+K +K Q +D+ M ++ + +H L +
Sbjct: 1634 IGEGQFGKVYTAVNMSTGELMALKEMK----FQPNDLQQLREMCDEIKIFEGIQHENLVK 1467
Query: 472 LYCCFQTKDRLFFVMEYVNGGDLMFQIQRSRKFDEPRS--RFYAAEVTSALMFLHQHGVI 529
Y KD + MEY + G I+ + K P R Y E+ A+ LH++ ++
Sbjct: 1466 YYGVEVHKDEMLMFMEYCDTGT----IEEAAKMGLPEYLIRRYTREIVLAVNHLHENSIV 1299
Query: 530 YRDLKLDNILLDAEGHCKLADFGMCKEGILNGVTTT----TFCGTPDYIAPEILQELE-- 583
+RD+K NI L + GH KL DFG C + + T GT Y+APE+ + +
Sbjct: 1298 HRDIKGANIFLTSNGHVKLGDFG-CSVKLKSHTTMPGEFHNLVGTTAYMAPEVFTQNDQG 1122
Query: 584 -YGPSVDWWALGVLMYEMMAGQPPFE--ADNEDDLFESILHDDVLYPVWLSKEAVSILKA 640
YG + D W+LG ++ EM G+ P+ +N +++ + P LS E L
Sbjct: 1121 GYGRAADIWSLGCVVIEMATGKRPWHDLDNNYQIMYKVGIGHKPAVPDSLSVEGKHFLDL 942
Query: 641 FMTKNPHKRLGCVASQ 656
M +P +R +ASQ
Sbjct: 941 IMCHDPAQR--ALASQ 900
>13066
Length = 551
Score = 91.7 bits (226), Expect = 1e-18, Method: Compositional matrix adjust.
Identities = 49/133 (36%), Positives = 73/133 (54%), Gaps = 4/133 (3%)
Frame = +3
Query: 466 HPYLTQLYCCFQTKDRLFFVMEYVNGGDLMFQIQRSRKFDEPRSRFYAAEVTSALMFLHQ 525
HPY+ Q++ Q + F M + GDL+ IQ E +++ + ++T+AL +LH
Sbjct: 153 HPYIIQIHSILQRXPKNFIFMRFAERGDLLTYIQEVGFVKEKQAKIWFYQMTTALNYLHS 332
Query: 526 HGVIYRDLKLDNILLDAEGHCKLADFGMCKEGILNG---VTTTTFCGTPDYIAPEILQEL 582
+ V +RDLK +NILL + + KLADFG I + T+CG+ Y APEI+
Sbjct: 333 YDVAHRDLKCENILLSSHFNVKLADFGFACACITESGEKYMSRTYCGSAAYAAPEIVYGA 512
Query: 583 EYGPSV-DWWALG 594
Y P V D W+LG
Sbjct: 513 PYAPKVADAWSLG 551
>26560
Length = 398
Score = 89.7 bits (221), Expect = 4e-18, Method: Compositional matrix adjust.
Identities = 45/121 (37%), Positives = 68/121 (56%), Gaps = 1/121 (0%)
Frame = -1
Query: 493 DLMFQIQRSRKFDEPRSRFYAAEVTSALMFLHQHGVIYRDLKLDNILLDAEGHCKLADFG 552
DL + + + F E RFYAAEV L +H V+YRDLK NILLD GH +++D G
Sbjct: 398 DLHYHLSQHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLG 219
Query: 553 MCKEGILNGVTTTTFCGTPDYIAPEILQELE-YGPSVDWWALGVLMYEMMAGQPPFEADN 611
+ + + GT Y+APE+L + + Y S DW++ G ++Y+++ G PF N
Sbjct: 218 LACD--FSKKRPHASVGTHGYMAPEVLMKGQSYDSSADWFSFGCMLYKLLKGHSPFRQHN 45
Query: 612 E 612
+
Sbjct: 44 Q 42
>13592
Length = 980
Score = 89.4 bits (220), Expect = 5e-18, Method: Compositional matrix adjust.
Identities = 67/253 (26%), Positives = 119/253 (47%), Gaps = 13/253 (5%)
Frame = +2
Query: 414 LGKGSFGKVMLAELKGKDEVYAVKVLKKDVILQDDDVDC--TMTEKRILALARKHPYLTQ 471
+G+G FGKV A E+ A+K ++ +Q + + E+ + KH L +
Sbjct: 8 IGQGRFGKVYTAVNNNTGELMAMK----EIAIQPGETRALKNVAEELKILEGIKHKNLVR 175
Query: 472 LYCCFQTKDRLFFVMEYVNGGDLMFQIQRSRKFDEPRSRFYAAEVTSALMFLHQHGVIYR 531
Y ++ L ME + G L ++ + E SR + A++ S + LH+HG+++R
Sbjct: 176 YYGIEVHREELLIFMELCSEGTLESLVELTGGLPEALSRRFTAQLLSGVAELHKHGIVHR 355
Query: 532 DLKLDNI-LLDAEGHCKLADFGMCKEGILNGVTTT-----TFCGTPDYIAPEILQELE-- 583
D+K NI L+D KL DFG + + TT + GT Y+APE+ +
Sbjct: 356 DIKTANIFLVDGSNSLKLGDFGSAVK--IQAHTTVPGELQGYVGTQAYMAPEVFTKTNSD 529
Query: 584 -YGPSVDWWALGVLMYEMMAGQPPFEA--DNEDDLFESILHDDVLYPVWLSKEAVSILKA 640
+G D W++G ++ EM +G+ P+ N +F+ + + P LS+E +
Sbjct: 530 GHGRLADIWSVGCVVVEMASGKRPWAQFDSNFQIMFKVGMGEKPQAPESLSQEGHDFIDH 709
Query: 641 FMTKNPHKRLGCV 653
+ +P +RL +
Sbjct: 710 CLQHDPKQRLSAI 748
>14126
Length = 1265
Score = 82.8 bits (203), Expect = 5e-16, Method: Compositional matrix adjust.
Identities = 75/295 (25%), Positives = 134/295 (45%), Gaps = 22/295 (7%)
Frame = +3
Query: 374 EEHRAASSPDGQLMSPGENGEVRQGQAKRLGL---------DEFNFIKVLGKGSFGKVML 424
EE +SP + M + + R GQ++ ++ + V+G G++G V
Sbjct: 66 EESSPKTSPAVRSMKTAISPKGRDGQSESAAKMSRRRDSTEQKYEEVAVIGNGAYGTVYK 245
Query: 425 A-ELKGKDEVYAVKVLKKDVILQDDDVDCTMTEKRILALARK-----HPYLTQLY----- 473
A +L+ + E A+K ++ L + + M R +++ ++ HP + +L
Sbjct: 246 ARDLRNQGEFVAMKRIR----LNNTEEGMPMMAIREISMLKQLEQYEHPNVVRLLDVSHN 413
Query: 474 CCFQTKDRLFFVMEYVNGGDLMFQIQR--SRKFDEPRSRFYAAEVTSALMFLHQHGVIYR 531
+ RL V EY+ DL + + S R + ++ + + FLH + +++R
Sbjct: 414 TITDREIRLNLVFEYIEH-DLATYLAKCPSPGLGPDRIKDLMLQLLNGVDFLHSNRIVHR 590
Query: 532 DLKLDNILLDAEGHCKLADFGMCKEGILNGVTTTTFCGTPDYIAPEILQELEYGPSVDWW 591
DLK N+L+ +G KLADFG+ + + + TT T Y +PE+L + EYG SVD W
Sbjct: 591 DLKPQNLLISKDGRLKLADFGLARIYSFH-MALTTVVVTLWYRSPEVLMQAEYGTSVDIW 767
Query: 592 ALGVLMYEMMAGQPPFEADNEDDLFESILHDDVLYPVWLSKEAVSILKAFMTKNP 646
+ G + E+ + F+ +E D + I L P E VS+ + P
Sbjct: 768 SCGCIFAELFTRRALFKGSSEFDQLKKIFEVIGLPPAGDWPEGVSVHRNSFRPTP 932
>25445
Length = 460
Score = 82.4 bits (202), Expect = 6e-16, Method: Composition-based stats.
Identities = 33/53 (62%), Positives = 39/53 (73%)
Frame = -1
Query: 243 HKFGIHNYKVPTFCDHCGSLLWGLLRQGLQCKVCKMNVHRRCETNVAPNCGVD 295
HKF H Y PTFCDHCGSLL+GL+ QGL+C C MN H+RCE +V CG+D
Sbjct: 397 HKFKAHTYGSPTFCDHCGSLLYGLIHQGLKCDSCDMNCHKRCEKHVPRLCGMD 239
Score = 47.0 bits (110), Expect = 3e-05, Method: Composition-based stats.
Identities = 21/54 (38%), Positives = 28/54 (51%)
Frame = -1
Query: 168 NGHKFMATYLRQPTYCSHCRDFIWGVIGKQGYQCQVCTCVVHKRCHELIITKCA 221
N HKF A PT+C HC ++G+I QG +C C HKRC + + C
Sbjct: 403 NLHKFKAHTYGSPTFCDHCGSLLYGLI-HQGLKCDSCDMNCHKRCEKHVPRLCG 245
>06405
Length = 1965
Score = 82.0 bits (201), Expect = 8e-16, Method: Compositional matrix adjust.
Identities = 59/200 (29%), Positives = 97/200 (48%), Gaps = 6/200 (3%)
Frame = +1
Query: 414 LGKGSFGKVMLAELKGKDEVYAVKVLKKDVILQDDDVDCTMTEKRILALARKHPYLTQLY 473
LG G +G V A K +++ AVK LK+D + +D ++ K + KHP L QL
Sbjct: 283 LGGGQYGDVYEAMWKRYNKIVAVKTLKEDTMALNDFLEEAAIMKEM-----KHPNLVQLL 447
Query: 474 CCFQTKDRLFFVMEYVNGGDLMFQIQRS-RKFDEPRSRFY-AAEVTSALMFLHQHGVIYR 531
+ + V E++ G+L+ ++ S R+ + P + Y A ++ S + +L I+R
Sbjct: 448 GVCTREPPFYIVTEFMPHGNLLDYLRSSTREENGPTALMYMATQIASGMAYLETKNFIHR 627
Query: 532 DLKLDNILLDAEGHCKLADFGMCKEGILNGVTTTTFCGTP---DYIAPEILQELEYGPSV 588
DL N L+ K+ADFG+ + ++ T T G + APE L +
Sbjct: 628 DLAARNCLVADSNMVKVADFGLAR--LMKDDTYTAHIGAKFPIKWTAPEGLAFNRFSTRS 801
Query: 589 DWWALGVLMYEMMA-GQPPF 607
D WA GVL++E+ G P+
Sbjct: 802 DIWAFGVLLWELATYGMSPY 861
>17722
Length = 680
Score = 81.6 bits (200), Expect = 9e-16, Method: Compositional matrix adjust.
Identities = 55/153 (35%), Positives = 75/153 (49%), Gaps = 8/153 (5%)
Frame = -3
Query: 588 VDWWALGVLMYEMMAGQPPFEADNEDDLFESILHDDVLYPVWLSKEAVSILKAFMTKNPH 647
VDWW GV+MYEMM G+ PF + D LFE IL +V +P LS+EA ++L + KNP
Sbjct: 678 VDWWGTGVVMYEMMCGRLPFYNRDHDVLFELILLQNVKFPRNLSEEAKTLLSGLLAKNPK 499
Query: 648 KRLGCVASQNGEDAIKQHPFFKEIDWVLLEQXXXXXXXXXXXXXXXDVNNFDQDFTREEP 707
+RLG S+ IK HPFF+ I+W L D ++F +E
Sbjct: 498 RRLG--GSEADVTEIKTHPFFQCINWDDLAAKKITPPWKPDVKSSWDTKYIPEEFAQESL 325
Query: 708 VLT------LVD--EAIVKQINQEEFKGFSYFG 732
LT L + + I + F+ FSY G
Sbjct: 324 HLTPGHDHPLAERLDPISEDAELPYFEQFSYHG 226
>01060
Length = 1800
Score = 79.7 bits (195), Expect = 4e-15, Method: Compositional matrix adjust.
Identities = 60/220 (27%), Positives = 104/220 (47%), Gaps = 6/220 (2%)
Frame = +1
Query: 404 GLDEFNFIKVLGKGSFGKVMLAELKGKDEVYAVKVLKKDVILQDDDVDCTMTEKRILALA 463
L + + +G+G++G V K + K+ K + L+ + + R +A+
Sbjct: 67 ALSDLTDFQKIGEGTYGVVY----KCRHRATGRKLAMKKIRLRGSEDGVPSSAIREIAML 234
Query: 464 R--KHPYLTQLYCCFQTKDRLFFVMEYVNGGDLMF--QIQRSRKFDEPRSRFYAAEVTSA 519
R +H + L +RLF V E+++ M+ + D + Y ++ +
Sbjct: 235 RELRHTNIVCLEDVIMEDERLFLVFEFLSMDLKMYIDKFPEGVVLDRRLVKSYVFQIVTG 414
Query: 520 LMFLHQHGVIYRDLKLDNILLDAEGHCKLADFGMCKEGILNGVTTTTFCGTPDYIAPEIL 579
+ F HQ +++RDLK N+L++ G K+ADFGM + L T T Y APEIL
Sbjct: 415 IXFCHQRRIVHRDLKPQNLLINHTGAIKIADFGMARTFALPVRAYTHEVVTLWYRAPEIL 594
Query: 580 Q-ELEYGPSVDWWALGVLMYEMMAGQPPFEADNE-DDLFE 617
+Y VD W++G + +M+ P F+ D+E D LF+
Sbjct: 595 MGASKYSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFK 714
>13212
Length = 1067
Score = 77.8 bits (190), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 40/101 (39%), Positives = 57/101 (56%), Gaps = 5/101 (4%)
Frame = -1
Query: 511 FYAAEVTSALMFLHQHGVIYRDLKLDNILLDAEGHCKLADFGMCKEGILNGVTTTTFCGT 570
+ E+ AL FLH+H VI+RD+K N+LL +G KLADFG+ + TF GT
Sbjct: 968 YVCHEMCMALDFLHRHHVIHRDIKAGNVLLTIDGEVKLADFGVSAKNTQTQQKRDTFIGT 789
Query: 571 PDYIAPEI-----LQELEYGPSVDWWALGVLMYEMMAGQPP 606
P ++APE+ L++ Y D W+LGV + E +PP
Sbjct: 788 PYWMAPEVVLCETLKDTPYDFKADIWSLGVTLIEFAQIEPP 666
>19094
Length = 898
Score = 75.1 bits (183), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 38/90 (42%), Positives = 51/90 (56%)
Frame = +1
Query: 519 ALMFLHQHGVIYRDLKLDNILLDAEGHCKLADFGMCKEGILNGVTTTTFCGTPDYIAPEI 578
L +LH I+RD+K NILL+ EGH KLADFG+ + T GTP ++APE+
Sbjct: 94 GL*YLHSRRKIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTPYWMAPEV 273
Query: 579 LQELEYGPSVDWWALGVLMYEMMAGQPPFE 608
+QE+ Y D W+LG+ EM G E
Sbjct: 274 IQEIGYDCVADIWSLGITALEMAEGNLHME 363
>21079
Length = 878
Score = 73.2 bits (178), Expect = 4e-13, Method: Compositional matrix adjust.
Identities = 41/144 (28%), Positives = 74/144 (51%), Gaps = 3/144 (2%)
Frame = +1
Query: 466 HPYLTQLYCCFQTKDRLFFVMEYVNGGDLMFQIQRSR-KFDEPRSRFYAAEVTSALMFLH 524
HP L L+ F+ + VME+V G+L ++ R E + ++ S + ++H
Sbjct: 1 HPKLLMLWDAFEAPRTMVLVMEFVGAGELFERVIRDDFVLTERDCVHFVRQICSGVGYMH 180
Query: 525 QHGVIYRDLKLDNILL--DAEGHCKLADFGMCKEGILNGVTTTTFCGTPDYIAPEILQEL 582
+++ DLK +N+L D K+ DFG+ + G + GTP++IAPE++
Sbjct: 181 TQSILHLDLKPENVLCVSDNSNQIKIIDFGLAR-FYKPGDSLQVLFGTPEFIAPEVVNYD 357
Query: 583 EYGPSVDWWALGVLMYEMMAGQPP 606
E + D W++GV+ Y +++G P
Sbjct: 358 EINFTTDMWSIGVICYILLSGLSP 429
>21433
Length = 590
Score = 72.4 bits (176), Expect = 6e-13, Method: Composition-based stats.
Identities = 41/100 (41%), Positives = 60/100 (60%)
Frame = +2
Query: 508 RSRFYAAEVTSALMFLHQHGVIYRDLKLDNILLDAEGHCKLADFGMCKEGILNGVTTTTF 567
R+ Y +++SAL + H VI+RD+K +N+LL +G K+ADFG TT
Sbjct: 170 RTACYIYQLSSALEYCHYRKVIHRDIKPENLLLGLKGDLKIADFGWSVHA--PSSRRTTM 343
Query: 568 CGTPDYIAPEILQELEYGPSVDWWALGVLMYEMMAGQPPF 607
CGT DY+ PE+++ + +VD W+LGVL YE + G PP
Sbjct: 344 CGTLDYLPPEMVEGKTHDENVDLWSLGVLCYEFLVGTPPL 463
>27546
Length = 426
Score = 70.9 bits (172), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 30/90 (33%), Positives = 53/90 (58%)
Frame = -1
Query: 466 HPYLTQLYCCFQTKDRLFFVMEYVNGGDLMFQIQRSRKFDEPRSRFYAAEVTSALMFLHQ 525
HP + Q++ Q ++F M Y GD++ I+++ DE +++ + ++ AL +LH
Sbjct: 303 HPNIIQIHSILQRGPKIFIFMRYAEKGDMLSHIKKTGPIDEAQTKVWFFQMAKALQYLHS 124
Query: 526 HGVIYRDLKLDNILLDAEGHCKLADFGMCK 555
H + +RDLK +NILL + K+ADFG +
Sbjct: 123 HDIAHRDLKCENILLSKRLNVKIADFGFAR 34
>01756
Length = 1858
Score = 69.7 bits (169), Expect = 4e-12, Method: Compositional matrix adjust.
Identities = 60/253 (23%), Positives = 108/253 (42%), Gaps = 17/253 (6%)
Frame = -3
Query: 414 LGKGSFGKVMLAELKGKDEVYAVKVLKKDVILQDDDVD----CTMTEKRILALARKHPYL 469
+G+G+FG+V A K +V A+K +L D++ + + E +IL L +
Sbjct: 1718 IGQGTFGEVFKARCKKTKQVVAMKK-----VLMDNEKEGFPITALREIKILQLLNHENVV 1554
Query: 470 TQLYCCF-------QTKDRLFFVMEYVNGGDLMFQIQRSRKFDEPRSRFYAAEVTSALMF 522
+ C + K + V E+ S F+ P + ++ + L +
Sbjct: 1553 DLIEICSTKATSANRYKSMFYLVFEFCEHDLAGLLSNMSVVFNLPEIKEVMKQLMNGLYY 1374
Query: 523 LHQHGVIYRDLKLDNILLDAEGHCKLADFGMCKEGILNGVTTTTFCG---TPDYIAPEIL 579
+H++ +++RD+K NIL+ +G KLADFG+ + +N + T Y PE+L
Sbjct: 1373 IHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRPPELL 1194
Query: 580 Q-ELEYGPSVDWWALGVLMYEMMAGQPPFEADNEDDLFESI--LHDDVLYPVWLSKEAVS 636
+ Y ++D W G +M EM P + E + I L + VW E +
Sbjct: 1193 LGDRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQNQLTLITQLCGSITPEVWPGVERLE 1014
Query: 637 ILKAFMTKNPHKR 649
+ + +KR
Sbjct: 1013 LYNSLDLPQGNKR 975
>04591
Length = 1117
Score = 69.7 bits (169), Expect = 4e-12, Method: Compositional matrix adjust.
Identities = 43/136 (31%), Positives = 71/136 (52%), Gaps = 2/136 (1%)
Frame = -2
Query: 479 KDRLFFVMEYVNGGDLMFQIQRSR-KFDEPRSRFYAAEVTSALMFLHQHGVIYRDLKLDN 537
K + + EY + DL + R KF + +++ + L ++H +++RD+K N
Sbjct: 981 KSTFYLIFEYCDY-DLAGLLNNLRVKFSLADKKNLMSQLLNGLFYIHTKQILHRDIKAAN 805
Query: 538 ILLDAEGHCKLADFGMCKEGILNGVTTTTFCGTPDYIAPE-ILQELEYGPSVDWWALGVL 596
ILL +G KLADFG+ + + + T T Y PE +L E EYGP +D W +G +
Sbjct: 804 ILLTRDGVLKLADFGLSRPWVKSKRLTNRVV-TLWYRPPELLLGEREYGPEIDMWGVGCI 628
Query: 597 MYEMMAGQPPFEADNE 612
M EM + +P + +E
Sbjct: 627 MAEMWSRKPLMQGRSE 580
>28638
Length = 1458
Score = 52.8 bits (125), Expect(2) = 4e-12, Method: Compositional matrix adjust.
Identities = 33/103 (32%), Positives = 55/103 (53%), Gaps = 4/103 (3%)
Frame = -1
Query: 509 SRFYAAEVTSALMFLH--QHGVIYRDLKLDNILL--DAEGHCKLADFGMCKEGILNGVTT 564
+R +A ++ +AL+FL + +I+ DLK +NILL K+ DFG G
Sbjct: 831 TRKFAQQLCTALLFLATPEMNIIHCDLKPENILLCNPKRSAIKIVDFG---SSCQLGQRI 661
Query: 565 TTFCGTPDYIAPEILQELEYGPSVDWWALGVLMYEMMAGQPPF 607
+ + Y +PE+L + Y ++D W+LG ++ EM G+PP
Sbjct: 660 YQYIQSRFYRSPEVLLGVPYDLAIDMWSLGCILVEMHTGEPPL 532
Score = 36.6 bits (83), Expect(2) = 4e-12, Method: Compositional matrix adjust.
Identities = 27/105 (25%), Positives = 50/105 (47%), Gaps = 5/105 (4%)
Frame = -3
Query: 405 LDEFNFIKVLGKGSFGKVMLAELKGKDEVYAVKVLKKDVILQDDDVDCTMTEKRILALAR 464
LD + ++GKGSFG+V+ A G E A+K++K ++ E ++L L
Sbjct: 1150 LDRYEIDSLIGKGSFGQVVKAYDHGDQEQVAIKIIKNKKPF----LNQAQIEVKLLELMN 983
Query: 465 KHP-----YLTQLYCCFQTKDRLFFVMEYVNGGDLMFQIQRSRKF 504
+H Y+ +L F ++ L V E ++ ++ + R+ F
Sbjct: 982 RHDADNXYYIVRLKRHFMFRNHLCLVFELLSYN--LYDLLRNTNF 854
>00392
Length = 668
Score = 68.2 bits (165), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 43/142 (30%), Positives = 73/142 (51%), Gaps = 4/142 (2%)
Frame = +3
Query: 482 LFFVMEYVNGGDLMFQIQRSRKFDEPRSRFYAAEVTSALMFLHQHG--VIYRDLKLDNIL 539
+ V E + G L ++R +K + + + +V L FLH VI+RDLK DNI
Sbjct: 171 IILVTELMTSGTLKTYLKRFKKPNVKILKNWCRQVLKGLYFLHTRTPPVIHRDLKCDNIF 350
Query: 540 LDA-EGHCKLADFGMCKEGILNGVTTTTFCGTPDYIAPEILQELEYGPSVDWWALGVLMY 598
+ G K+ D G+ + N + GTP+++APE+ +E Y +VD +A G+ M
Sbjct: 351 ITGPTGSVKIGDLGLA--TLKNQSFAKSVIGTPEFMAPEMYEE-HYDEAVDVYAFGMCML 521
Query: 599 EMMAGQPPF-EADNEDDLFESI 619
EM + + P+ E N +++ +
Sbjct: 522 EMASSEYPYSECSNAAQIYKRV 587
>29581
Length = 1278
Score = 68.2 bits (165), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 54/225 (24%), Positives = 94/225 (41%), Gaps = 31/225 (13%)
Frame = -2
Query: 477 QTKDRLFFVMEYVNGGDLMFQIQRSRKFDEPRSRFYAAEVTSALMFLHQHGVIYRDLKLD 536
++ D LF VMEY F E + + ++ L +LH+ +I+RDLK+
Sbjct: 1139 KSLDSLFLVMEYCEQDLASLLDNMPAPFSESQVKCIVLQLLKGLRYLHEAFIIHRDLKVS 960
Query: 537 NILLDAEGHCKLADFGMCKEGILNGVTTTTFCGTPDYIAPEIL-QELEYGPSVDWWALGV 595
N+L+ +G K+ADFG+ + T T Y APE+L + ++D W+ G
Sbjct: 959 NLLMTDKGCVKIADFGLARNYGKPQKPMTPKVVTLWYRAPELLFGSKTHSTAIDMWSAGC 780
Query: 596 LMYEMMAGQPPFEADNEDDLFESILH-----DDVLYP----------------------- 627
++ E++ +P ++ E I+ +D ++P
Sbjct: 779 ILGELLGHKPLMPGRSDLQQIELIMELLGTPNDTIWPGFSQLPAFEQFTLKKQPYNNLRH 600
Query: 628 --VWLSKEAVSILKAFMTKNPHKRLGCVASQNGEDAIKQHPFFKE 670
WLS+ + +L +P KR ED + +H +FKE
Sbjct: 599 TFPWLSESGIRLLNGLFMYHPQKR------ATAEDCL-EHSYFKE 486
>35187
Length = 593
Score = 67.8 bits (164), Expect = 2e-11, Method: Composition-based stats.
Identities = 35/118 (29%), Positives = 55/118 (46%)
Frame = -3
Query: 168 NGHKFMATYLRQPTYCSHCRDFIWGVIGKQGYQCQVCTCVVHKRCHELIITKCAGLKKQE 227
+GH F +PTYC HC D +WG+IG GY C+VC VVH RC + +++ C+ +
Sbjct: 321 HGHFFTKKTFHKPTYCHHCTDILWGLIG-VGYVCEVCNFVVHDRCMKTVVSPCSSIATYL 145
Query: 228 TPDQVGSQRFSVNMPHKFGIHNYKVPTFCDHCGSLLWGLLRQGLQCKVCKMNVHRRCE 285
+ V H + + FC C L ++C++C+ H C+
Sbjct: 144 IKNPVA---------HCWSEPGHFKRKFCSVCRKRLED--STAIRCEICEYYAHLDCQ 4
Score = 51.6 bits (122), Expect = 1e-06, Method: Composition-based stats.
Identities = 21/50 (42%), Positives = 26/50 (52%)
Frame = -3
Query: 243 HKFGIHNYKVPTFCDHCGSLLWGLLRQGLQCKVCKMNVHRRCETNVAPNC 292
H F + PT+C HC +LWGL+ G C+VC VH RC V C
Sbjct: 315 HFFTKKTFHKPTYCHHCTDILWGLIGVGYVCEVCNFVVHDRCMKTVVSPC 166
>01392
Length = 1806
Score = 67.4 bits (163), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 51/176 (28%), Positives = 77/176 (43%), Gaps = 32/176 (18%)
Frame = -1
Query: 506 EPRSRFYAAEVTSALMFLHQHGVIYRDLKLDNIL---LDAEGHCKLADFGMCKEGILNGV 562
E + + AL FLH G+ +RDLK +NIL LD K+ DF + +G
Sbjct: 1794 EREASLVVRHIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGISCDGD 1615
Query: 563 TTTTF-----CGTPDYIAPEILQ-----ELEYGPSVDWWALGVLMYEMMAGQPPFEA--- 609
T T G+ +Y+APE++ Y D W+LG+++Y M+ G PPF
Sbjct: 1614 GTKTPELLTPVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILYIMLCGYPPFYGQCG 1435
Query: 610 ------------DNEDDLFESILHDDVLYPV--W--LSKEAVSILKAFMTKNPHKR 649
D +D LF SI +P W +S A +++ + + P KR
Sbjct: 1434 EDCGWNRGEACHDCQDMLFNSIQDGHYKFPSQEWTSISSSAKDLIRHLLVREPRKR 1267
>32957
Length = 645
Score = 65.5 bits (158), Expect = 8e-11, Method: Composition-based stats.
Identities = 27/54 (50%), Positives = 38/54 (70%)
Frame = +3
Query: 551 FGMCKEGILNGVTTTTFCGTPDYIAPEILQELEYGPSVDWWALGVLMYEMMAGQ 604
F +C E +G T TFCGT +Y+APE+ + EYG VDWW LG+L++E++A Q
Sbjct: 3 FALCVEK--SGGRTRTFCGTREYMAPEVHERKEYGKEVDWWGLGILLHELLAAQ 158
>11185
Length = 473
Score = 63.9 bits (154), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 44/144 (30%), Positives = 65/144 (45%), Gaps = 30/144 (20%)
Frame = +1
Query: 510 RFYAAEVTSALMFLHQHGVIYRDLKLDNILLDAEGHCKLADFGMCK-------------- 555
R + + + L ++H G+++ DL+ +LLD G K ADFG+ K
Sbjct: 10 RDFGIHLVTGLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFA 189
Query: 556 -----------EGILNGVTTTTFCGTPDYIAPEILQELEYGPSVDWWALGVLMYEMMAG- 603
E ++ V T+ G+P Y+APE+ Q E D WALG + YEM +G
Sbjct: 190 EAGDQWNIQSAEEMMKQVPTS---GSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSGS 360
Query: 604 ----QPPFEADNEDDLFESILHDD 623
+P E N L ES+L D
Sbjct: 361 RLSAKPSPEFLN---LLESLLQKD 423
>09007
Length = 1440
Score = 63.9 bits (154), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 72/285 (25%), Positives = 117/285 (41%), Gaps = 26/285 (9%)
Frame = -1
Query: 361 NNIRKALSFDNRGEEHRAAS-SPDGQLMSPGENGEVRQGQAKRL-GLDEFNFIKVLGKGS 418
+++A+ GE R+ S SP MS + VR + K+L D K LG+G
Sbjct: 1020 GKLKRAIMRSGGGEPGRSLSPSPPEHRMSRPVSAVVRPARGKQLISKDCVALSKSLGQGH 841
Query: 419 FGKVMLA---ELKGKDEVYAVKVLKKDVILQDDDVDCTMTEKRILALARKHPYLTQLYCC 475
FG V A G+ AVK L KD I +D + E I+ + H + ++Y
Sbjct: 840 FGTVRQAIWTAESGEKVQVAVKCLSKDKIHKDGQE--FLKETAIMQML-DHENIVRVYGV 670
Query: 476 FQTKDRLFFVMEYVNGGDLMF---------------QIQRSRKFDEPRSRFYAAEVTSAL 520
VM+ NG D+M ++ F PR ++ +V +
Sbjct: 669 ---------VMD--NGADIMLVTELAPMRSLLECVKEVSARVDFSVPRLCDFSQQVCDGM 523
Query: 521 MFLHQHGVIYRDLKLDNILLDAEGHCKLADFGM-----CKEGILNGVTTTTFCGTPDYIA 575
+L +++RDL NILL ++ K++D G+ + T + A
Sbjct: 522 SYLESKRLVHRDLAARNILLFSKSKVKISDVGVSGALGAGKEYYQSQQTIHLQNAVAWCA 343
Query: 576 PEILQELEYGPSVDWWALGVLMYEMMA-GQPPFEADNEDDLFESI 619
PE + L + + D WA GVL++E G P+ N + E++
Sbjct: 342 PESFRNLCFSSASDVWAFGVLLWEFFTHGFQPWAGLNGQQIMEAV 208
>21808
Length = 1011
Score = 62.8 bits (151), Expect = 5e-10, Method: Compositional matrix adjust.
Identities = 46/177 (25%), Positives = 75/177 (42%), Gaps = 8/177 (4%)
Frame = +1
Query: 453 TMTEKRILALAR-----KHPYLTQLYCCFQTKDRLFFVMEYVNGGDLMFQIQ-RSRKFDE 506
TM K LA A+ +HP L QLY D +F + E + G L+ +Q + R
Sbjct: 55 TMDPKDFLAEAQIMKKLRHPKLIQLYAVCTQDDPIFIITELMKNGSLLEFLQGKGRVLKL 234
Query: 507 PRSRFYAAEVTSALMFLHQHGVIYRDLKLDNILLDAEGHCKLADFGMCKEGILNGVTTTT 566
P A++ + +L I+RDL NIL+ K+ADFG+ + +
Sbjct: 235 PALIDIGAQIACGMAYLESQNYIHRDLAARNILVSDNNTVKIADFGLARVIKEDEYEARV 414
Query: 567 FCGTP-DYIAPEILQELEYGPSVDWWALGVLMYEMMA-GQPPFEADNEDDLFESILH 621
P + APE + D W+ G+L+ E + G+ P+ ++ + H
Sbjct: 415 GARFPIKWTAPEAANYNRFTIKSDVWSFGILLTETVTYGRVPYPGMTNAEVLHQVEH 585
>16708
Length = 1397
Score = 61.6 bits (148), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 77/318 (24%), Positives = 121/318 (38%), Gaps = 63/318 (19%)
Frame = -1
Query: 410 FIKVLGKGSFGKVMLAELKGKDEVYAVKVLKKDVILQDDDVDCTMTEKRILALARKHP-- 467
++VLGKG FGKV A L E A+K + C + + AL R
Sbjct: 1391 ILQVLGKGVFGKVYEARLLSTHEKAALKT----------SILCHHSLDEVEALGRIEGGF 1242
Query: 468 YLTQLYCCFQTK---DRLFFVMEYVNGGDLMFQIQRSRKFDEPRSRF--------YAAEV 516
YL Q++ + T ++ ++ + G L + K E R+ A +
Sbjct: 1241 YLAQMFGAWVTCLPFPKMNILLHFYEMGPLC-NVYAHYKNKEMPIRWSNPAMVCCIAGQX 1065
Query: 517 TSALMFLHQHGVIYRDLKLDNILLDAEGHCKLADFGMCK---------EGILNGVTT--T 565
AL +H+ GV++ D+K DN+L+DA G+CKL D+G+ + E +G T T
Sbjct: 1064 VCALEHIHELGVVHMDVKADNVLVDAHGNCKLTDYGIAQLYKVYPAPTETHSSGCTNKRT 885
Query: 566 TFCGTPDYIAP-EILQELEYGPSVDWWALGVLMYEMMAG------------------QPP 606
+ P + P E E G D++ LG +++ + P
Sbjct: 884 FYTRPPATMTPSERFSEEGDGIGTDYFRLGQMLWTLTGAVLLHVWVSRPPKLPDWCRTPE 705
Query: 607 FEADNEDDLFESILHDD------VLYPVWL--------------SKEAVSILKAFMTKNP 646
E D E + H D V W + I + F + P
Sbjct: 704 SELSGMSDFIEKLCHGDPNMRLGVTLNCWTHMFLCPLXRLGRIPAPFGEPIAEIFGLQGP 525
Query: 647 HKRLGCVASQNGEDAIKQ 664
H+RL AS N + A +Q
Sbjct: 524 HRRL---ASNNTQAATRQ 480
>26711
Length = 405
Score = 61.6 bits (148), Expect = 1e-09, Method: Composition-based stats.
Identities = 37/105 (35%), Positives = 54/105 (51%), Gaps = 8/105 (7%)
Frame = -2
Query: 515 EVTSALMFLHQHGVIYRDLKLDNILL--DAEGHCKLADFGMCK------EGILNGVTTTT 566
+V L +H GV++ DLK N+LL D +L DFG+ + E LN
Sbjct: 392 QVLDILQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARKLYPPQETFLNH----- 228
Query: 567 FCGTPDYIAPEILQELEYGPSVDWWALGVLMYEMMAGQPPFEADN 611
GTP + +PE L + D W +GVL Y +++GQ PF+AD+
Sbjct: 227 --GTPGFTSPEALDVKPISTASDVWGVGVLAYILLSGQSPFQADS 99
>38560
Length = 479
Score = 61.6 bits (148), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 30/87 (34%), Positives = 48/87 (55%), Gaps = 1/87 (1%)
Frame = -3
Query: 565 TTFCGTPDYIAPEILQELEY-GPSVDWWALGVLMYEMMAGQPPFEADNEDDLFESILHDD 623
TT CG+P Y APE++ LEY G D W++GVL+Y ++ G PF+ + L +
Sbjct: 411 TTCCGSPAYAAPELISGLEYLGSEADIWSMGVLLYALLCGYLPFDDEKXSHL*QKNQKRK 232
Query: 624 VLYPVWLSKEAVSILKAFMTKNPHKRL 650
P WLS++ +L+ + +P R+
Sbjct: 231 DEVPEWLSEDTTKLLEGMLQTDPSHRI 151
>12786
Length = 460
Score = 60.1 bits (144), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 39/132 (29%), Positives = 62/132 (46%), Gaps = 22/132 (16%)
Frame = -3
Query: 499 QRSRKFDEPRSRFYAAEVTSALMFLHQHGVIYRDLKLDNILLDAEGHCKLADFGMCK--E 556
++ + D +FY E+ A+ LH GVI+ DLK N +L A G+ KL DFG+ +
Sbjct: 434 KQEQGLDRMMIKFYWREMLRAVKALHNEGVIHSDLKPANFMLVA-GNLKLIDFGIANTLQ 258
Query: 557 GILNGVTTTTFCGTPDYIAPEILQ--------------------ELEYGPSVDWWALGVL 596
V + GTP Y++PE + + + G D W+LG +
Sbjct: 257 QDKTSVLKDSRVGTPSYMSPEAIMAACDDSADDSMEEDGHRTKPKYKVGVRSDVWSLGCI 78
Query: 597 MYEMMAGQPPFE 608
+Y M+ G+ PF+
Sbjct: 77 LYNMVYGRTPFQ 42
>01966
Length = 1735
Score = 58.9 bits (141), Expect = 7e-09, Method: Compositional matrix adjust.
Identities = 45/164 (27%), Positives = 74/164 (45%), Gaps = 4/164 (2%)
Frame = -1
Query: 437 KVLKKDVILQDDDVDCTMTEKRILALAR--KHPYLTQLYCCFQTKDRLFFVMEYVNGGDL 494
K+ K + L+ + + R +A+ R +H + L +RLF V E+++
Sbjct: 1630 KLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTNIVCLEDVIMEDERLFLVFEFLSMDLK 1451
Query: 495 MF--QIQRSRKFDEPRSRFYAAEVTSALMFLHQHGVIYRDLKLDNILLDAEGHCKLADFG 552
M+ + D + Y ++ + + F HQ +++RDLK N+L++ G K+ADFG
Sbjct: 1450 MYIDKFPEGVVLDRRLVKSYVFQIVTGINFCHQRRIVHRDLKPQNLLINHTGAIKIADFG 1271
Query: 553 MCKEGILNGVTTTTFCGTPDYIAPEILQELEYGPSVDWWALGVL 596
M + L T T Y APEIL + P W G L
Sbjct: 1270 MARTFALPVRAYTHEVVTLWYRAPEILMGPQSTPPX--WTCGAL 1145
>04852
Length = 1462
Score = 58.9 bits (141), Expect = 7e-09, Method: Compositional matrix adjust.
Identities = 55/227 (24%), Positives = 97/227 (42%), Gaps = 29/227 (12%)
Frame = +1
Query: 430 KDEVYAVKVLKKDV--ILQDDDVDCTMTEKRILALARKHPYLTQLYCCFQTKDRLFFVME 487
K AVK+L+ V + + D V K + + + L CC Q L+ ++E
Sbjct: 16 KASTVAVKMLRDIVTAVEEQDFVQELQVMKAVKKMGSHINIVNFLGCCTQGGP-LWVIVE 192
Query: 488 YVNGGDLMFQIQRSR-------KFDEPRS------------------RFYAAEVTSALMF 522
+ G+L ++ R KF P+ YA ++ + F
Sbjct: 193 FAKNGNLRDFLESCRDGINGYGKFVSPQDPGWYTKTPGGHVIRRKNLLSYAFQIARGMEF 372
Query: 523 LHQHGVIYRDLKLDNILLDAEGHCKLADFGMCKEGILNGVTTTTFCGTP-DYIAPEILQE 581
L I+RDL N+L+ E K+ADFG+ + G + + P ++APE L +
Sbjct: 373 LASRKCIHRDLAARNVLVTEEHVLKIADFGLSRTG--DYYKKRSGGRLPVKWMAPEALFD 546
Query: 582 LEYGPSVDWWALGVLMYEMMA-GQPPFEADNEDDLFESILHDDVLYP 627
+ Y D W+ GV+++E+ + G P+ + ++L+ +L D P
Sbjct: 547 MRYTTKSDVWSFGVVLWEIFSLGGMPYASIPNEELYSKLLDDAYRMP 687
>14116
Length = 1017
Score = 58.2 bits (139), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 50/205 (24%), Positives = 95/205 (46%), Gaps = 16/205 (7%)
Frame = -1
Query: 414 LGKGSFGKV-----MLAELKGKDEVYAVKVLKKDVILQDDDVDCTMTEKRILALARKHPY 468
+GKG+FG V L E KG D + AVK L + ++ ++ + E I+
Sbjct: 612 IGKGNFGCVKRGFLTLPEQKG-DILVAVKTLHNNNP-REIELQSFLQEALIMKDFHHSNV 439
Query: 469 LTQLYCCFQTKDRLFFVMEYVNGGDLMFQIQRSRKFDEPRSR---FYAAEVTSALMFLHQ 525
LT + C D V+ ++ GDL+ I+ + +P + Y ++ + +L
Sbjct: 438 LTLIGICLNLDDMPLVVLPFMKHGDLLTYIRDDQH--QPTIKDLIMYGVDIARGMDYLAG 265
Query: 526 HGVIYRDLKLDNILLDAEGHCKLADFGMCKEGILNGVTTTTFCGTPD--------YIAPE 577
++RDL N +LD + H K+ADFG+ ++ + + + + ++A E
Sbjct: 264 LKFVHRDLAARNCMLDEDFHVKVADFGLARD-----IYEKEYYSSENKKAKLPVKWMALE 100
Query: 578 ILQELEYGPSVDWWALGVLMYEMMA 602
L++ Y D W+ GV+++E++
Sbjct: 99 SLEKGNYDSKTDVWSYGVVLWELLT 25
>19761
Length = 473
Score = 57.8 bits (138), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 29/91 (31%), Positives = 50/91 (54%), Gaps = 2/91 (2%)
Frame = -3
Query: 512 YAAEVTSALMFLHQHG--VIYRDLKLDNILLDAEGHCKLADFGMCKEGILNGVTTTTFCG 569
+ + SAL ++H H +++RDLK NI + +G +L D G+ ++ T+ G
Sbjct: 408 WLMQTASALNYMHTHTPVILHRDLKPQNIYVTEKGDVRLGDLGLARKLTGPADFATSQVG 229
Query: 570 TPDYIAPEILQELEYGPSVDWWALGVLMYEM 600
T Y++PEIL + Y D W+LG + Y++
Sbjct: 228 TIMYLSPEILSQQPYNSKSDIWSLGCVFYDI 136
>11353
Length = 454
Score = 57.4 bits (137), Expect = 2e-08, Method: Composition-based stats.
Identities = 32/105 (30%), Positives = 48/105 (45%)
Frame = +1
Query: 240 NMPHKFGIHNYKVPTFCDHCGSLLWGLLRQGLQCKVCKMNVHRRCETNVAPNCGVDARGI 299
+ PH+F + Y PT+CD C LLWG + G C C N H +C+ V C + +
Sbjct: 133 SQPHRFEKYTYTTPTYCDFCQQLLWGFSKTGTHCVDCGYNCHDKCQPLVPKTCS-KLKSV 309
Query: 300 AKVLADLGVTPDKITNSGQRRKKLIAGAESPQPASGSSPSEEDRS 344
+ A V +T SG ++ +SG+ PS E+ S
Sbjct: 310 SDTSAQSAVI---VTRSGV--------SDVTAASSGTGPSFENFS 411
Score = 43.9 bits (102), Expect = 2e-04, Method: Composition-based stats.
Identities = 19/55 (34%), Positives = 25/55 (45%)
Frame = +1
Query: 170 HKFMATYLRQPTYCSHCRDFIWGVIGKQGYQCQVCTCVVHKRCHELIITKCAGLK 224
H+F PTYC C+ +WG K G C C H +C L+ C+ LK
Sbjct: 142 HRFEKYTYTTPTYCDFCQQLLWG-FSKTGTHCVDCGYNCHDKCQPLVPKTCSKLK 303
>03508
Length = 1463
Score = 57.0 bits (136), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 37/126 (29%), Positives = 63/126 (50%), Gaps = 2/126 (1%)
Frame = +1
Query: 484 FVMEYVNGGDLMFQIQRSRKFDEPRSRFYAAEVTSALMFLHQHGVIYRDLKLDNILLDAE 543
+ E+VN D Q + F + RFY E+ AL F H G+++RD+K N+++D E
Sbjct: 811 LIFEHVNNTDFK---QLYQTFTDYDIRFYLYELMKALDFCHSMGIMHRDVKPHNVMIDHE 981
Query: 544 G-HCKLADFGMCKEGILNGVTTTTFCGTPDYIAPEILQELE-YGPSVDWWALGVLMYEMM 601
+L D+G+ E G+ + + PE+L + + Y S+D W+LG + M+
Sbjct: 982 NKKLRLIDWGLA-EFYHPGMEYNVRVASRYFKGPELLLDYQMYDYSLDMWSLGCMFASMI 1158
Query: 602 AGQPPF 607
+ P
Sbjct: 1159FRKEPL 1176
>17975
Length = 449
Score = 56.2 bits (134), Expect = 4e-08, Method: Compositional matrix adjust.
Identities = 44/139 (31%), Positives = 73/139 (52%), Gaps = 4/139 (2%)
Frame = +3
Query: 419 FGKVMLAELKGKDEVYAVKVLKKDVILQDDDVDCT--MTEKRILALARKHPYLTQLYCCF 476
F V LA E AVKV+ K + D+V + E R + L +HP + +LY
Sbjct: 6 FAVVKLARHVFTGEKVAVKVIDKTKL---DEVSRSHLFQEVRCMKLV-QHPNVVRLYEVI 173
Query: 477 QTKDRLFFVMEYVNGGDLMFQIQR-SRKFDEPRSRFYAAEVTSALMFLHQHGVIYRDLKL 535
T+ +L+ ++E +GGD+ I R S +E ++ Y ++ A+ + H+ V++RDLK
Sbjct: 174 DTQTKLYLILELGDGGDMYDYIMRHSGGLEEKLAKRYFRQIVEAISYCHKLHVVHRDLKP 353
Query: 536 DNIL-LDAEGHCKLADFGM 553
+N++ + G KL DFG
Sbjct: 354 ENVVFFEKPGLVKLTDFGF 410
>03942
Length = 912
Score = 56.2 bits (134), Expect = 4e-08, Method: Compositional matrix adjust.
Identities = 27/60 (45%), Positives = 38/60 (63%), Gaps = 1/60 (1%)
Frame = +2
Query: 615 LFESILHDDVLYPVWLSKEAVSILKAFMTKNPHKRLGCVASQNGEDAIKQHPFF-KEIDW 673
L+ +L ++ Y V++ ++ + FMTKNP KRLGCV SQ E AI H FF ++IDW
Sbjct: 29 LYMQVLCNEYAYLVYMFSMSLFCIFQFMTKNPAKRLGCVTSQGAEKAIFIHAFFHQKIDW 208
>37602
Length = 804
Score = 56.2 bits (134), Expect = 4e-08, Method: Compositional matrix adjust.
Identities = 28/76 (36%), Positives = 41/76 (53%)
Frame = -1
Query: 476 FQTKDRLFFVMEYVNGGDLMFQIQRSRKFDEPRSRFYAAEVTSALMFLHQHGVIYRDLKL 535
+ +++L+ MEY GG + + EP+ F E L +LH+ G ++RD+K
Sbjct: 312 YLRREKLWIAMEYCGGGSMQDIYHVTGPLTEPQIAFVCRETLKGLHYLHRRGKMHRDIKG 133
Query: 536 DNILLDAEGHCKLADF 551
NILL EG KLADF
Sbjct: 132 ANILLTEEGDVKLADF 85
>11780
Length = 1713
Score = 52.0 bits (123), Expect(2) = 4e-08, Method: Compositional matrix adjust.
Identities = 45/172 (26%), Positives = 82/172 (47%), Gaps = 2/172 (1%)
Frame = +3
Query: 412 KVLGKGSFGKVMLAELKGKDEVYAVKVLKKDVILQDDDVDCTMTEKRILALARKHPYLTQ 471
+ +GKG FG V +G+ A+K LK +D + E ++ R H L +
Sbjct: 615 EAIGKGDFGDVYKGMYRGQP--VAIKQLKD----KDRGEQSFLQEASVMTSLR-HDNLVR 773
Query: 472 LYCCFQTKDRLFFVMEYVNGGDLM-FQIQRSRKFDEPRSRF-YAAEVTSALMFLHQHGVI 529
L + +F V E++ G+L+ + R R + + +A + +A+ +L ++
Sbjct: 774 LIGVV-LGETIFLVTEFMGKGNLVEYLRSRGRSVITKKDQINFATDTCAAMEYLESKRLV 950
Query: 530 YRDLKLDNILLDAEGHCKLADFGMCKEGILNGVTTTTFCGTPDYIAPEILQE 581
+RDL N+L+ +G K++DFG+ K G + T+ + APE L+E
Sbjct: 951 HRDLAARNVLVHDDGKAKVSDFGLAKFG---DFSQTSVKFPIKWTAPEALRE 1097
Score = 23.9 bits (50), Expect(2) = 4e-08, Method: Compositional matrix adjust.
Identities = 17/75 (22%), Positives = 38/75 (50%), Gaps = 5/75 (6%)
Frame = +1
Query: 580 QELEYGPSVDWWALGVLMYEMMA-GQPPFEADNEDDLFESILHDDVLY----PVWLSKEA 634
+++++ D W+ G+L++E+ + G+ P+ D+ ++H + Y P E
Sbjct: 1093 EKIKFTSKSDMWSFGILLWEIYSFGRVPYPRIPLTDV---VMHVERGYRMEAPEGCPPEI 1263
Query: 635 VSILKAFMTKNPHKR 649
SI+K +P++R
Sbjct: 1264 YSIMKQAWELDPNER 1308
>17300
Length = 480
Score = 55.8 bits (133), Expect = 5e-08, Method: Composition-based stats.
Identities = 33/109 (30%), Positives = 60/109 (55%), Gaps = 5/109 (4%)
Frame = +1
Query: 516 VTSALMFLHQHGVIYRDLKLDNILLDAEGHCKLADFGMCKE---GILNGVTTTTFCGTP- 571
++S + L G ++RDL NIL++ CK+ADFG+ +E G TT P
Sbjct: 1 ISSGMGXLADMGYVHRDLAARNILVNEILVCKVADFGLSREIESDTTEGAYTTKGGKIPV 180
Query: 572 DYIAPEILQELEYGPSVDWWALGVLMYEMMA-GQPPFEADNEDDLFESI 619
+ APE + ++ + D W+ GV+M+E+M+ G+ P+ + D+ +++
Sbjct: 181 RWTAPEAIAYRKFTSASDVWSFGVVMWEVMSYGERPYWNWSNQDVIKAV 327
>04138
Length = 800
Score = 55.1 bits (131), Expect = 9e-08, Method: Compositional matrix adjust.
Identities = 30/99 (30%), Positives = 51/99 (51%), Gaps = 4/99 (4%)
Frame = +1
Query: 520 LMFLHQHGVIYRDLKLDNILLDAEGHCKLADFGMCKEGILNGVTTTTFCG---TPDYIAP 576
L ++H++ +++RD+K NIL+ +G KLADFG+ + +N + T Y P
Sbjct: 52 LYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRPP 231
Query: 577 E-ILQELEYGPSVDWWALGVLMYEMMAGQPPFEADNEDD 614
E +L + Y ++D W G +M EM P + E +
Sbjct: 232 ELLLGDRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQN 348
>00715
Length = 1788
Score = 54.3 bits (129), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 41/169 (24%), Positives = 71/169 (42%), Gaps = 23/169 (13%)
Frame = +1
Query: 479 KDRLFFVMEYVNGGDLMFQIQ-RSRKFDEPRSRFYAAEVTSALMFLHQHGVIYRDLKLDN 537
+D + MEYV +L + + D A ++ L +LH +++ DLK N
Sbjct: 151 EDGAWLAMEYVGPLNLQTILNDHQQDIDSSMRLSLALQMARGLHYLHSINIVHLDLKPAN 330
Query: 538 ILLDAEGHCKLADFGMC------------KEGIL----------NGVTTTTFCGTPDYIA 575
LL + ++ADFG C +EG + G GT Y A
Sbjct: 331 CLLTRDLKLRIADFGCCHQLTPTGLDMGEREGGMAGNELELTPVQGAWKNELAGTLAYRA 510
Query: 576 PEILQELEYGPSVDWWALGVLMYEMMAGQPPFEADNEDDLFESILHDDV 624
PE+L+ L+ D ++LG+ +++M Q P+E + ++ D+
Sbjct: 511 PELLKGLQPSVRSDVYSLGITLWQMCTRQGPYEGVPAHAVVYQVVSKDL 657
>30339
Length = 384
Score = 53.5 bits (127), Expect = 3e-07, Method: Composition-based stats.
Identities = 29/63 (46%), Positives = 42/63 (66%), Gaps = 8/63 (12%)
Frame = -2
Query: 375 EHRAASSPDGQLMSPGENGEVR-------QGQAK-RLGLDEFNFIKVLGKGSFGKVMLAE 426
+ + S+ +G L++ ++G +R +G++ R L +FNFIKVLGKGSFGKVMLAE
Sbjct: 191 KRQGVSTGEGGLLAANDHGSLRARSPSSDRGRSSDRFHLHDFNFIKVLGKGSFGKVMLAE 12
Query: 427 LKG 429
KG
Sbjct: 11 RKG 3
>22804
Length = 967
Score = 53.5 bits (127), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 21/54 (38%), Positives = 28/54 (51%)
Frame = -3
Query: 240 NMPHKFGIHNYKVPTFCDHCGSLLWGLLRQGLQCKVCKMNVHRRCETNVAPNCG 293
+ PH+F + Y PT+CD C LLWG + G C C N H +C+ V C
Sbjct: 839 SQPHRFEKYTYTTPTYCDFCQQLLWGFSKTGTHCVDCGYNCHDKCQPLVPKTCS 678
Score = 35.8 bits (81), Expect = 0.058, Method: Compositional matrix adjust.
Identities = 17/52 (32%), Positives = 23/52 (44%)
Frame = -3
Query: 170 HKFMATYLRQPTYCSHCRDFIWGVIGKQGYQCQVCTCVVHKRCHELIITKCA 221
H+F PTYC C+ +WG K G C C H +C L+ C+
Sbjct: 830 HRFEKYTYTTPTYCDFCQQLLWG-FSKTGTHCVDCGYNCHDKCQPLVPKTCS 678
>07940
Length = 1336
Score = 52.8 bits (125), Expect = 5e-07, Method: Compositional matrix adjust.
Identities = 35/108 (32%), Positives = 56/108 (51%), Gaps = 3/108 (2%)
Frame = -3
Query: 512 YAAEVTSALMFLHQHGVIYRDLKLDNILLDAEGHCKLADFGMCKE-GILNGVTTTTFCGT 570
YA +V + +L I+RDL N+L+ E K+ADFG+ + + TT
Sbjct: 332 YAYQVARGMEYLASKQCIHRDLAARNVLVAEEYVLKIADFGLTRNLQQFDYYRKTTDGRL 153
Query: 571 P-DYIAPEILQELEYGPSVDWWALGVLMYEMMA-GQPPFEADNEDDLF 616
P ++APE L + +Y D W+ GVL++E+ G P+ + +DLF
Sbjct: 152 PVKWMAPEALFDRKYTSKSDVWSYGVLLWEIFTLGGNPYPSVPVEDLF 9
Score = 37.7 bits (86), Expect = 0.018, Method: Compositional matrix adjust.
Identities = 27/86 (31%), Positives = 44/86 (51%), Gaps = 5/86 (5%)
Frame = -3
Query: 414 LGKGSFGKVMLAELKG--KDE---VYAVKVLKKDVILQDDDVDCTMTEKRILALARKHPY 468
LG+G+FG VM E G KD AVK+LK+D D ++ + E ++ + KH
Sbjct: 818 LGEGAFGLVMKGEAMGIFKDNNSVTVAVKMLKEDA--TDREMMDLIREMEMMKVIGKHKN 645
Query: 469 LTQLYCCFQTKDRLFFVMEYVNGGDL 494
+ L C + L+ ++E+ G+L
Sbjct: 644 IINLLGCCTQRGALYVIVEFAPHGNL 567
>32000
Length = 644
Score = 51.2 bits (121), Expect = 1e-06, Method: Composition-based stats.
Identities = 44/154 (28%), Positives = 66/154 (42%), Gaps = 29/154 (18%)
Frame = -1
Query: 547 KLADFGMCKEGILNGVTTTTFCGTPDYIAPEILQELE-YGPSVDWWALGVLMYEMMAGQP 605
K+ADFG+ + L T T T Y APEIL Y VD W+LG + EMM +
Sbjct: 569 KIADFGLARVFGLPVRTYTHEVITLWYRAPEILLGCRFYSVPVDIWSLGCIFVEMMTRRA 390
Query: 606 PFEADNEDDLFESILH-----DDVLYP-----------------------VWLSKEAVSI 637
F D+E D I D+ ++P V LSK + +
Sbjct: 389 LFPGDSEIDQLYRIFRTLGTPDEKVWPGVSKLPDYKPTFPKWPLKNLETVVSLSKVGLDL 210
Query: 638 LKAFMTKNPHKRLGCVASQNGEDAIKQHPFFKEI 671
LK +T NP++R+ ++ +HP+F ++
Sbjct: 209 LKRMLTYNPNRRISARSAM-------RHPYFNDM 129
>19361
Length = 685
Score = 51.2 bits (121), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 19/78 (24%), Positives = 42/78 (53%)
Frame = -1
Query: 242 PHKFGIHNYKVPTFCDHCGSLLWGLLRQGLQCKVCKMNVHRRCETNVAPNCGVDARGIAK 301
PH F + N+ +C+ C + +WGL+ QG++C+ C + H++C + C + + + +
Sbjct: 319 PHVFKVQNFNGLNWCELCANFMWGLIAQGVKCQDCGVQTHKKCSERMPNECMPNMKYVKR 140
Query: 302 VLADLGVTPDKITNSGQR 319
+ GV +T + ++
Sbjct: 139 L---YGVDLTTVTKANKQ 95
Score = 41.2 bits (95), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 18/51 (35%), Positives = 26/51 (50%)
Frame = -1
Query: 170 HKFMATYLRQPTYCSHCRDFIWGVIGKQGYQCQVCTCVVHKRCHELIITKC 220
H F +C C +F+WG+I QG +CQ C HK+C E + +C
Sbjct: 316 HVFKVQNFNGLNWCELCANFMWGLIA-QGVKCQDCGVQTHKKCSERMPNEC 167
>12672
Length = 773
Score = 50.4 bits (119), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 31/114 (27%), Positives = 56/114 (49%), Gaps = 4/114 (3%)
Frame = +3
Query: 518 SALMFLHQHGVIYRDLKLDNILLDAEGHCKLADFGMCKEGILNGVTT----TTFCGTPDY 573
S + +L+ +G ++RD+K NILLD+E K+ DF T + GT Y
Sbjct: 24 SGIQYLNDNGHVHRDIKTANILLDSEYTAKVGDFATVVSAPSGEGKTVQNASVVIGTAAY 203
Query: 574 IAPEILQELEYGPSVDWWALGVLMYEMMAGQPPFEADNEDDLFESILHDDVLYP 627
+APE + + +D ++ GV++ E++ G + E+ S + ++V P
Sbjct: 204 LAPEAIH-FDVSTKLDSYSFGVVLLEVITGLVAQDYSREERTLSSHIMENVEEP 362
>12442
Length = 468
Score = 50.1 bits (118), Expect = 4e-06, Method: Composition-based stats.
Identities = 23/34 (67%), Positives = 25/34 (73%), Gaps = 1/34 (2%)
Frame = +3
Query: 641 FMTKNPHKRLGCVASQNGEDAIKQHPFF-KEIDW 673
FMTKNP KRLGCV SQ E AI H FF ++IDW
Sbjct: 105 FMTKNPAKRLGCVTSQGAEKAIFIHAFFHQKIDW 206
>19301
Length = 712
Score = 48.5 bits (114), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 40/171 (23%), Positives = 71/171 (41%)
Frame = +2
Query: 382 PDGQLMSPGENGEVRQGQAKRLGLDEFNFIKVLGKGSFGKVMLAELKGKDEVYAVKVLKK 441
P ++ E++Q + + ++ LG G+ G V L +L E AVK ++
Sbjct: 233 PVWTIIGKAAAAELKQQDDWEIPFESITDLEWLGSGAQGAVFLGKLCA--EEVAVKKVR- 403
Query: 442 DVILQDDDVDCTMTEKRILALARKHPYLTQLYCCFQTKDRLFFVMEYVNGGDLMFQIQRS 501
D T+ R L HP + +MEY G L ++
Sbjct: 404 ---------DIKETDIRNLR-KLNHPNIISFKGVCTQAPCYCIIMEYCPYGQLYEVLRDG 553
Query: 502 RKFDEPRSRFYAAEVTSALMFLHQHGVIYRDLKLDNILLDAEGHCKLADFG 552
++ ++ ++ S + +LH H +I+RDLK N+L+ K++DFG
Sbjct: 554 KEIPPALVLDWSKQIASGMNYLHSHKIIHRDLKSPNVLVAKNDVVKISDFG 706
>01718
Length = 959
Score = 48.1 bits (113), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 59/228 (25%), Positives = 97/228 (42%), Gaps = 17/228 (7%)
Frame = +3
Query: 395 VRQGQAKRLGLDEFNFIKVLGKGSFGKVMLAELKGKDEVYAVKVLKKDVILQDDDVDCTM 454
+R + LD+F + +G G F +V + +V A+K+ TM
Sbjct: 117 LRHAVSALTRLDDF-ICEKIGAGFFSEVFKVTHRITGQVMALKM-------------NTM 254
Query: 455 TEKR------ILALAR-KHPYLTQLYCCFQTKDRLFFVMEYVNGGDLMFQIQRSRKFDEP 507
T R + L R +H + + + +L + EY+ G+L Q K DE
Sbjct: 255 TSNRHNMLREVQLLNRLQHANILRFMGVCVHEGQLHALTEYIPSGNLE---QLLEKKDEE 425
Query: 508 RSRFYAAEVTSALM----FLHQHGVIYRDLKLDNILLDAEG----HCKLADFGMCKE--G 557
++T L +LH I+RDL NIL+ E H +ADFG+ +
Sbjct: 426 LPWTQRIQLTLGLARGLDYLHSTRFIHRDLTSKNILIRREDNHGYHAVIADFGLATKIPD 605
Query: 558 ILNGVTTTTFCGTPDYIAPEILQELEYGPSVDWWALGVLMYEMMAGQP 605
L+ T G+P ++APE+L Y D +++G++M E+ A P
Sbjct: 606 PLDKEKLPT-VGSPYWMAPEVLNGHFYNERADLFSVGIIMCEITARIP 746
>29590
Length = 320
Score = 45.4 bits (106), Expect = 8e-05, Method: Composition-based stats.
Identities = 19/39 (48%), Positives = 23/39 (58%)
Frame = +3
Query: 569 GTPDYIAPEILQELEYGPSVDWWALGVLMYEMMAGQPPF 607
GTPDY+APE+L D W+LGVL Y M+ PF
Sbjct: 60 GTPDYVAPEVLDYEPLSIQTDMWSLGVLSYVMLTACSPF 176
>07291
Length = 833
Score = 45.4 bits (106), Expect = 8e-05, Method: Compositional matrix adjust.
Identities = 24/102 (23%), Positives = 52/102 (50%), Gaps = 6/102 (5%)
Frame = +1
Query: 512 YAAEVTSALMFLHQHGVIYRDLKLDNILLDAEGHCKLADFGMCKEGILNGVTTTTFCGTP 571
+ ++ + +L + V++R+L N ++ +G +L+D+G+ G L + T +P
Sbjct: 64 FGRQIADGMAYLQEVKVVHRNLAARNCIVTEDGRLQLSDYGVT--GSLFPQSYYTADDSP 237
Query: 572 -----DYIAPEILQELEYGPSVDWWALGVLMYEMMA-GQPPF 607
++APE + + D WA GV+++E++ G P+
Sbjct: 238 ARDLVKWMAPETIDNFHFSSKSDVWAFGVVLWELLTRGITPY 363
>07836
Length = 1478
Score = 45.4 bits (106), Expect = 8e-05, Method: Compositional matrix adjust.
Identities = 38/138 (27%), Positives = 57/138 (41%), Gaps = 18/138 (13%)
Frame = -1
Query: 481 RLFFVMEYVNGGDLMFQIQRSRKFDEPRSRFYAAEVTSALMFLH--------QHGVIYRD 532
+LF + +Y G L SR D A L LH + + +RD
Sbjct: 1331 QLFLITDYHENGSL-HDYLLSRVLDSSEMLALAHSAICGLAHLHIEIFGTRGKPAIAHRD 1155
Query: 533 LKLDNILLDAEGHCKLADFGMCKEGILNG----VTTTTFCGTPDYIAPEILQEL------ 582
+K NIL+ G C +AD G+ I V GT Y+APE+L+ L
Sbjct: 1154 IKSKNILVKKNGTCCIADLGLAVRYISESNEVDVAPNPRQGTKRYMAPEVLEMLLNVKNF 975
Query: 583 EYGPSVDWWALGVLMYEM 600
+ D +A G++M+E+
Sbjct: 974 DAFKQADMYAFGLVMWEI 921
>20152
Length = 445
Score = 45.1 bits (105), Expect = 9e-05, Method: Composition-based stats.
Identities = 22/75 (29%), Positives = 40/75 (53%), Gaps = 1/75 (1%)
Frame = +1
Query: 576 PEILQELEY-GPSVDWWALGVLMYEMMAGQPPFEADNEDDLFESILHDDVLYPVWLSKEA 634
PEIL Y P+VD W+LGV++Y ++ G+ PF+ N+ + I+ P +S +
Sbjct: 1 PEILLGDSYDAPAVDVWSLGVILYMLVVGEAPFQEANDSETLTMIMDCRYQIPPHISHKC 180
Query: 635 VSILKAFMTKNPHKR 649
+++ + + P R
Sbjct: 181 QDLIEKMLQREPVDR 225
>27274
Length = 396
Score = 45.1 bits (105), Expect = 1e-04, Method: Composition-based stats.
Identities = 15/34 (44%), Positives = 28/34 (82%)
Frame = -1
Query: 577 EILQELEYGPSVDWWALGVLMYEMMAGQPPFEAD 610
E+L+ ++GP+VD W+LG+L++E+++G PFE +
Sbjct: 375 ELLRGQQHGPTVDMWSLGILLHELLSGHVPFEPE 274
>17932
Length = 597
Score = 33.5 bits (75), Expect(2) = 2e-04, Method: Composition-based stats.
Identities = 12/22 (54%), Positives = 15/22 (68%)
Frame = -2
Query: 590 WWALGVLMYEMMAGQPPFEADN 611
WW+LGV YEM+ G PF D+
Sbjct: 596 WWSLGVCAYEMLFGCTPFTDDD 531
Score = 29.6 bits (65), Expect(2) = 2e-04, Method: Composition-based stats.
Identities = 14/44 (31%), Positives = 23/44 (52%)
Frame = -3
Query: 630 LSKEAVSILKAFMTKNPHKRLGCVASQNGEDAIKQHPFFKEIDW 673
+SKEA ++ ++ S+ G ++QHPFFK +DW
Sbjct: 460 VSKEARDLISQLLSDG--------KSRLGWPELQQHPFFKTVDW 353
>11404
Length = 563
Score = 43.5 bits (101), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 42/165 (25%), Positives = 79/165 (47%), Gaps = 10/165 (6%)
Frame = +1
Query: 386 LMSPGENGEVRQGQAKRLGLDEFNFIKVLGKGSFGKVMLAELKGKDEVYAVKVLKKDVIL 445
++SPGE D + ++GKGSFG+V+ A +E A+K++K
Sbjct: 112 IISPGEKWA-----------DRYEIDSLIGKGSFGQVVKAYDHTDNEQVAIKIIKN---- 246
Query: 446 QDDDVDCTMTEKRILALARKHP-----YLTQLYCCFQTKDRLFFVMEYVNGGDLMFQIQR 500
+ ++ E ++L + +H Y+ +L F + L V E ++ ++ + R
Sbjct: 247 KKPFLNQAQIEVKLLEMMNRHDTDNKYYIVRLKRHFMFRSHLCLVFELLSYN--LYDLLR 420
Query: 501 SRKF---DEPRSRFYAAEVTSALMFLH--QHGVIYRDLKLDNILL 540
+ F +R +A ++ +AL+FL + +I+ DLK +NILL
Sbjct: 421 NTNFRGVSLNLTRKFAQQLCTALLFLATPEMSIIHCDLKPENILL 555
>33586
Length = 551
Score = 43.5 bits (101), Expect = 3e-04, Method: Composition-based stats.
Identities = 16/49 (32%), Positives = 31/49 (63%)
Frame = +2
Query: 468 YLTQLYCCFQTKDRLFFVMEYVNGGDLMFQIQRSRKFDEPRSRFYAAEV 516
++ L+ FQT+ +L+ ++E++ GGDL ++ + F E +FY AE+
Sbjct: 404 FIVHLHYAFQTEGKLYLILEFLRGGDLFTRLSKEVMFTEEDVKFYLAEL 550
>17253
Length = 483
Score = 42.4 bits (98), Expect = 8e-04, Method: Composition-based stats.
Identities = 29/114 (25%), Positives = 50/114 (43%), Gaps = 16/114 (14%)
Frame = -1
Query: 458 RILALARK---HPYLTQLYCCFQTKDRLFFVMEYVNGGDLMFQIQRSRKFDE-------- 506
R L++ RK HP + C D +ME+ GDL+ R R+ D
Sbjct: 402 RELSIMRKLPRHPNVVSFMGCCTMSDPALILMEFCCHGDLL-SFLRKRRPDRTVFLTSTA 226
Query: 507 ----PRSRF-YAAEVTSALMFLHQHGVIYRDLKLDNILLDAEGHCKLADFGMCK 555
R F +A V + + + +++RD+ N+L+ CK++DFG+ +
Sbjct: 225 NDLTARDFFSFALHVARGMAHVANNKIVHRDVAARNVLISERNVCKVSDFGLSR 64
>18481
Length = 437
Score = 42.0 bits (97), Expect = 8e-04, Method: Composition-based stats.
Identities = 35/123 (28%), Positives = 57/123 (46%), Gaps = 8/123 (6%)
Frame = -1
Query: 441 KDVILQDDDVDCTMT----EKRILALARKHPYLTQLYCCFQTKDRLFFVMEYVNGG-DLM 495
KD+ ++ + +D E ++ +HP L +Y K VME + + +
Sbjct: 407 KDIAVKIEAIDVKHQLLHYEAKVYEQIGRHPGLPTMYHYGTEKHFNALVMELLGPSLEEL 228
Query: 496 FQIQRSRKFDEPRSRFYAAEVTSALMFLHQHGVIYRDLKLDNILLDAEGHCK---LADFG 552
F I + R+F + ++ S L F+HQ I+RDLK DN L+ HC + DFG
Sbjct: 227 FVICK-RRFTLKTILMVSDQLLSRLEFIHQKCFIHRDLKPDNFLMGLGRHCHRLYIIDFG 51
Query: 553 MCK 555
+ K
Sbjct: 50 LSK 42
>14477
Length = 493
Score = 41.2 bits (95), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 37/144 (25%), Positives = 67/144 (46%), Gaps = 2/144 (1%)
Frame = -1
Query: 414 LGKGSFGKVM--LAELKGKDEVYAVKVLKKDVILQDDDVDCTMTEKRILALARKHPYLTQ 471
LG G+FG VM + L ++ A+KVLK + D V + ++ + H ++ +
Sbjct: 466 LGAGNFGSVMKGVCRLDDREIPVAIKVLKNADL--DPSVQSELIKEAEVMKKMDHMHIVR 293
Query: 472 LYCCFQTKDRLFFVMEYVNGGDLMFQIQRSRKFDEPRSRFYAAEVTSALMFLHQHGVIYR 531
L + + + V+E G L + +++ +V+ + +L + ++R
Sbjct: 292 LIGLCEG-ETMMLVLELAKLGPLNKFLPKNKHLPLWNILELMWQVSQGMEYLEANKFVHR 116
Query: 532 DLKLDNILLDAEGHCKLADFGMCK 555
DL NILL E K++DFGM K
Sbjct: 115 DLAARNILLCDEHFAKISDFGMSK 44
>18401
Length = 463
Score = 39.7 bits (91), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 21/59 (35%), Positives = 33/59 (55%), Gaps = 3/59 (5%)
Frame = -3
Query: 565 TTFCGTPDYIAPEILQELEYGPSVDWWALGVLMYEMMAGQPPFEA-DNEDDL--FESIL 620
+T T Y APE++ EL + D W++G +M+E+ G F+ DN++ L E IL
Sbjct: 458 STIVSTRHYRAPEVILELGWSHPCDVWSVGCIMFELYTGYTLFQTHDNKEHLAMMERIL 282
>30743
Length = 569
Score = 39.3 bits (90), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 16/38 (42%), Positives = 23/38 (60%)
Frame = +2
Query: 247 IHNYKVPTFCDHCGSLLWGLLRQGLQCKVCKMNVHRRC 284
+H ++ P CD CG LL G+ QG C+ +M VH+ C
Sbjct: 338 MHTFEKPKECDVCGKLLRGIFFQGYLCQDNQMAVHKEC 451
>02638
Length = 1490
Score = 38.9 bits (89), Expect = 0.007, Method: Compositional matrix adjust.
Identities = 16/41 (39%), Positives = 27/41 (65%)
Frame = +1
Query: 569 GTPDYIAPEILQELEYGPSVDWWALGVLMYEMMAGQPPFEA 609
GT ++APE+L+ YG + D W++G +M EM +PP+ +
Sbjct: 22 GTIAFMAPEVLRGESYGRACDVWSVGCVMIEMCTCRPPWNS 144
>18996
Length = 491
Score = 38.5 bits (88), Expect = 0.009, Method: Compositional matrix adjust.
Identities = 22/78 (28%), Positives = 41/78 (52%), Gaps = 4/78 (5%)
Frame = +2
Query: 529 IYRDLKLDNILLDAEGHCKLADFGMCK----EGILNGVTTTTFCGTPDYIAPEILQELEY 584
I+RDL NIL+D K++DFG+ + +G G++ + +PE ++ ++
Sbjct: 2 IHRDLAARNILVD-RSCVKISDFGLAQFANADGYYYGISQRDI--PIKWYSPEAIETCKF 172
Query: 585 GPSVDWWALGVLMYEMMA 602
D W+ GV ++EM +
Sbjct: 173 SSYSDVWSYGVTLFEMFS 226
>17516
Length = 453
Score = 37.4 bits (85), Expect = 0.022, Method: Composition-based stats.
Identities = 16/40 (40%), Positives = 27/40 (67%), Gaps = 1/40 (2%)
Frame = -3
Query: 566 TFCGTPDYIAPEI-LQELEYGPSVDWWALGVLMYEMMAGQ 604
T GTP Y+APE+ LQ+ +Y D ++L ++++E+ GQ
Sbjct: 442 TLAGTPVYMAPEVLLQKGQYDMKADVYSLAIILWELWYGQ 323
>26009
Length = 886
Score = 35.4 bits (80), Expect = 0.092, Method: Compositional matrix adjust.
Identities = 40/163 (24%), Positives = 63/163 (38%), Gaps = 12/163 (7%)
Frame = +2
Query: 406 DEFNFIKVLGKGSFGKVMLAELKGKDEVYAVKVLKKDVILQDDDVDCT-----MTEKRIL 460
+ ++ K LG+G++GKV+LA + A+K+L K CT E ++
Sbjct: 416 EHYDVCKELGRGTYGKVVLARCRHTGTQVALKLLPK---------SCTKLREFQREFQLS 568
Query: 461 ALARKHPYLTQLY-CCFQTKDRLFFVMEYVNGGDLMFQIQRSRKFDEPRSRFYAAEVTSA 519
H + Y FQT+ F E+ GDL I + E R + E
Sbjct: 569 YFLSPHANIIDTYNVAFQTRSSYVFAQEHAVLGDLFDAIPPQQGMRESRGQIR-HETARV 745
Query: 520 LMFLHQHGVIY------RDLKLDNILLDAEGHCKLADFGMCKE 556
LH + R+ + L C+L DFGM ++
Sbjct: 746 RARLHAQQAVSPS*HQARERAYPHAGLFP---CELMDFGMTRK 865
>31120
Length = 439
Score = 34.7 bits (78), Expect = 0.16, Method: Composition-based stats.
Identities = 15/42 (35%), Positives = 27/42 (64%), Gaps = 1/42 (2%)
Frame = +1
Query: 577 EILQELEYGPSV-DWWALGVLMYEMMAGQPPFEADNEDDLFE 617
E++ + Y P + D W+LGV+++ M+ G+ PF+ N + L E
Sbjct: 1 EVVCGVPYDPKMADAWSLGVILFIMLNGKMPFDDSNLNKLLE 126
>00638
Length = 1595
Score = 34.3 bits (77), Expect = 0.17, Method: Compositional matrix adjust.
Identities = 18/51 (35%), Positives = 27/51 (52%)
Frame = +2
Query: 484 FVMEYVNGGDLMFQIQRSRKFDEPRSRFYAAEVTSALMFLHQHGVIYRDLK 534
+ E+VN D Q + F + RFY E+ AL F H G+++RD+K
Sbjct: 356 LIFEHVNNTDFK---QLYQTFTDYDIRFYLYELMKALDFCHSMGIMHRDVK 499
>26052
Length = 562
Score = 34.3 bits (77), Expect = 0.18, Method: Composition-based stats.
Identities = 20/48 (41%), Positives = 27/48 (56%), Gaps = 1/48 (2%)
Frame = -1
Query: 391 ENGEVRQGQAKRLGLD-EFNFIKVLGKGSFGKVMLAELKGKDEVYAVK 437
+N + Q A + L ++ F K+LG GSFGKVM + K E AVK
Sbjct: 439 QNNQYHQKMASSMCLPXQYLFXKLLGVGSFGKVMALQHKDTGETLAVK 296
>02913
Length = 855
Score = 34.3 bits (77), Expect = 0.18, Method: Composition-based stats.
Identities = 17/43 (39%), Positives = 24/43 (55%)
Frame = +3
Query: 694 DVNNFDQDFTREEPVLTLVDEAIVKQINQEEFKGFSYFGEDLM 736
D + FD FTR+ PV + D + INQ FKGF+Y ++
Sbjct: 6 DTSQFDTKFTRQTPVDSPDDTILSDSINQ-VFKGFTYIAPSVL 131
>23319
Length = 2235
Score = 32.7 bits (73), Expect = 0.57, Method: Composition-based stats.
Identities = 14/46 (30%), Positives = 25/46 (54%), Gaps = 1/46 (2%)
Frame = +3
Query: 576 PEILQELEYGPSVDWWALGVLMYEMM-AGQPPFEADNEDDLFESIL 620
P++ Y S+D W+ G + E+ AG+P F +++DD + I
Sbjct: 3 PDVYXAKMYSTSIDMWSAGCIFAELANAGRPLFPGNDDDDQLKRIF 140
>31489
Length = 329
Score = 31.2 bits (69), Expect = 1.6, Method: Composition-based stats.
Identities = 19/67 (28%), Positives = 32/67 (47%)
Frame = +3
Query: 473 YCCFQTKDRLFFVMEYVNGGDLMFQIQRSRKFDEPRSRFYAAEVTSALMFLHQHGVIYRD 532
Y F+ +F +ME DL I + E R++ ++ L ++H V++RD
Sbjct: 75 YHDFKDIHVVFDLME----SDLHRIIYSDQPLTEEHIRYFLYQILRGLKYIHSANVVHRD 242
Query: 533 LKLDNIL 539
LK N+L
Sbjct: 243 LKPSNLL 263
>15549
Length = 470
Score = 30.8 bits (68), Expect = 1.9, Method: Composition-based stats.
Identities = 15/32 (46%), Positives = 21/32 (65%)
Frame = -1
Query: 406 DEFNFIKVLGKGSFGKVMLAELKGKDEVYAVK 437
DEF I+ +GKG +G V A+ K ++ YAVK
Sbjct: 218 DEFECIEQMGKGGYGIVFRAKNKVDEQEYAVK 123
>36643
Length = 601
Score = 30.8 bits (68), Expect = 2.2, Method: Composition-based stats.
Identities = 18/55 (32%), Positives = 28/55 (50%), Gaps = 5/55 (9%)
Frame = +1
Query: 367 LSFDNRGEEHRAASSPDGQLMSPGE-----NGEVRQGQAKRLGLDEFNFIKVLGK 416
SF +GEE + S+ +++P E G + R GL +N+IK+LGK
Sbjct: 208 FSFTGQGEEELSFSAGQQLILAPKEVQPQVRGWLLASVGGRKGLVPYNYIKILGK 372
>37063
Length = 455
Score = 30.0 bits (66), Expect = 3.5, Method: Composition-based stats.
Identities = 23/78 (29%), Positives = 37/78 (47%), Gaps = 13/78 (16%)
Frame = -2
Query: 533 LKLDNIL---LDAEGHCKLADFGMCKEGILNGVTTTTF-----CGTPDYIAPEIL----- 579
LK +NIL LD K+ DF + +G T T G+ +Y+APE++
Sbjct: 454 LKPENILCEHLDEVVPLKICDFDLASGINCDGDGTKTPELLTPVGSAEYMAPEVVDAWVG 275
Query: 580 QELEYGPSVDWWALGVLM 597
+ Y D W+LG+++
Sbjct: 274 ESFSYDKRCDMWSLGIIL 221
>36481
Length = 806
Score = 30.0 bits (66), Expect = 3.7, Method: Compositional matrix adjust.
Identities = 38/140 (27%), Positives = 63/140 (45%), Gaps = 14/140 (10%)
Frame = +2
Query: 415 GKGSFGKVMLAE--LKGKDEVYAVKVLKK-DVILQDDDVDCTMTEKRILALARKHPYLTQ 471
G+G+FGKV+ + LKG D A+K++K D + ++ + EK L K P+
Sbjct: 389 GEGTFGKVVQCKDLLKGDD--IALKIIKNVDKYREAAKLEINVLEK----LREKDPHAKH 550
Query: 472 LYCCFQTKDRLFFVMEYVNGGDLMFQIQRSRKFDEPRSRFYAA-----------EVTSAL 520
+ C Q D +Y + F + FD + Y A ++ A+
Sbjct: 551 M--CVQMLDWF----DYHGHVCISFHMLGLSVFDFLKDNSYGAYPIEQVRHISYQLCYAV 712
Query: 521 MFLHQHGVIYRDLKLDNILL 540
FLH++ + + DLK +NIL
Sbjct: 713 NFLHENQLTHTDLKPENILF 772
>17637
Length = 447
Score = 28.9 bits (63), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/36 (38%), Positives = 22/36 (61%), Gaps = 1/36 (2%)
Frame = +1
Query: 573 YIAPEILQELEYGPSVDWWALGVLMYEMMA-GQPPF 607
+++ E LQ+ Y D W+ GVLM+EM G+ P+
Sbjct: 115 WLSLEALQKSHYNEGSDVWSFGVLMWEMCTLGKLPY 222
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000302898 | hsapiens_gene_ensembl |
Serine/threonine-protein kinase 13 (EC 2.7.11.1) (Aurora/Ipl1/Eg2
protein 2) (Aurora/Ipl1-related kinase 3) (Aurora-C).
[Source:Uniprot/SWISSPROT;Acc:Q9UQB9]
(309 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
21433 159 1e-60
03240 120 7e-28
15910 117 7e-27
12721 115 2e-26
30755 110 5e-25
18484 107 4e-24
14420 107 5e-24
01707 105 2e-23
18921 102 2e-22
14126 101 4e-22
01060 100 1e-21
09606 98 4e-21
00300 94 5e-20
01392 92 2e-19
13066 88 4e-18
06405 88 4e-18
01756 88 4e-18
21079 87 9e-18
09007 85 3e-17
27546 84 9e-17
17975 84 1e-16
01718 83 1e-16
00392 81 4e-16
04591 81 5e-16
13592 80 8e-16
31885 78 5e-15
13212 77 6e-15
00486 74 5e-14
26560 72 3e-13
25019 49 3e-13
20152 71 6e-13
18663 71 7e-13
01966 70 7e-13
19301 70 1e-12
19094 69 2e-12
27405 68 4e-12
11780 65 2e-11
26711 66 2e-11
29581 65 4e-11
14477 63 1e-10
19761 62 2e-10
14116 62 2e-10
21808 62 2e-10
04852 62 3e-10
37602 51 2e-09
04138 57 8e-09
28157 57 1e-08
38560 56 2e-08
00715 56 2e-08
07940 55 3e-08
12672 55 4e-08
27274 54 1e-07
28638 53 1e-07
07291 52 3e-07
20559 49 5e-07
12786 50 9e-07
17722 50 9e-07
03508 50 2e-06
11185 49 4e-06
16708 47 1e-05
26009 47 1e-05
02638 46 2e-05
07833 45 3e-05
20640 45 3e-05
32957 45 4e-05
17253 44 6e-05
07836 44 9e-05
31489 43 1e-04
17300 42 3e-04
31789 41 7e-04
11404 39 0.003
29590 38 0.004
00394 37 0.008
01106 37 0.009
31120 37 0.012
18481 37 0.013
18401 37 0.014
37063 36 0.021
36002 35 0.034
21800 32 0.22
00638 32 0.47
03106 30 1.3
20160 30 1.8
38046 29 1.9
13078 29 2.7
36481 29 2.8
03063 28 3.7
20513 28 3.8
06342 28 4.8
16350 28 5.3
21418 28 6.1
17637 27 7.9
18874 27 9.4
>21433
Length = 590
Score = 159 bits (403), Expect(2) = 1e-60, Method: Compositional matrix adjust.
Identities = 84/137 (61%), Positives = 101/137 (73%)
Frame = +2
Query: 141 QRTATIIEELADALTYCHDKKVIHRDIKPENLLLGFRGEVKIADFGWSVHTPSLRRKTMC 200
+RTA I +L+ AL YCH +KVIHRDIKPENLLLG +G++KIADFGWSVH PS RR TMC
Sbjct: 167 KRTACYIYQLSSALEYCHYRKVIHRDIKPENLLLGLKGDLKIADFGWSVHAPSSRRTTMC 346
Query: 201 GTLDYLPPEMIEGRTYDEKVDLWCIGVLCYELLVGYPPFESASHSETYRRILKVDVRFPL 260
GTLDYLPPEM+EG+T+DE VDLW +GVLCYE LVG PP + + P
Sbjct: 347 GTLDYLPPEMVEGKTHDENVDLWSLGVLCYEFLVGTPPLRPSPTRPPTPASPRWTSGSPS 526
Query: 261 SMPLGARDLISRLLRYQ 277
+ GARDLIS+LLR++
Sbjct: 527 IVTPGARDLISKLLRHR 577
Score = 91.7 bits (226), Expect(2) = 1e-60, Method: Compositional matrix adjust.
Identities = 42/61 (68%), Positives = 49/61 (80%)
Frame = +3
Query: 86 HQLRREIEIQAHLQHPNILRLYNYFHDARRVYLILEYAPRGELYKELQKSEKLDEQRTAT 145
HQLRREIEIQ+HL+H NILR++ YFHD RVYLILE+AP+GELYKELQ+ K DE
Sbjct: 3 HQLRREIEIQSHLRHDNILRMFGYFHDKTRVYLILEFAPKGELYKELQRCHKFDENEQHA 182
Query: 146 I 146
I
Sbjct: 183 I 185
>03240
Length = 1683
Score = 120 bits (301), Expect = 7e-28, Method: Compositional matrix adjust.
Identities = 85/284 (29%), Positives = 134/284 (47%), Gaps = 53/284 (18%)
Frame = -3
Query: 43 FEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLRREIEIQAHLQHPN 102
FE + LG G FG V L R ++ + A+K L KS + K ++ E +I A +
Sbjct: 1285 FEKIKTLGVGAFGEVSLCRKNDTGMLYAMKTLRKSDVLKRNQVAHVKAERDILAEADNEW 1106
Query: 103 ILRLYNYFHDARRVYLILEYAPRGELYKELQKSEKLDEQRTATIIEELADALTYCHDKKV 162
+++LY F D +Y +++Y P G+L L + E LDE + EL A+ H
Sbjct: 1105 VVKLYYSFQDHNYLYFVMDYVPGGDLMGLLIRMEILDEPLARFYVAELVQAIESVHRMGF 926
Query: 163 IHRDIKPENLLLGFRGEVKIADFG------WSVHT------------------------- 191
IHRDIKP+N+L+ G +K+ DFG W+ ++
Sbjct: 925 IHRDIKPDNILIDRNGHIKLTDFGLCTGFRWTHNSKYYQRDGTHARQDSMEVKCQLDEQC 746
Query: 192 ------PSLRRK---------TMCGTLDYLPPEMIEG-RTYDEKVDLWCIGVLCYELLVG 235
P RR+ ++ GT +Y+ PE++ Y D W +GV+ +E+LVG
Sbjct: 745 QCEILKPLERRRKREQRCLAHSLVGTPNYIAPEVLSRLGGYTSVCDWWSVGVILFEMLVG 566
Query: 236 YPPFESASHSET------YRRILKVDVRFPLSMPLGARDLISRL 273
+PPF + + +ET ++ +LK+ LS P A+DLI RL
Sbjct: 565 HPPFYANTPAETQYKVINWKDMLKIPRESNLSQP--AKDLILRL 440
>15910
Length = 1361
Score = 117 bits (292), Expect = 7e-27, Method: Compositional matrix adjust.
Identities = 62/182 (34%), Positives = 102/182 (56%), Gaps = 8/182 (4%)
Frame = +2
Query: 127 ELYKELQKSEKLDEQRTATIIEELADALTYCHDKKVIHRDIKPENLL---LGFRGEVKIA 183
EL+ + + E+ A I ++ + Y H V+HRD+KPENLL + ++K+A
Sbjct: 422 ELFDRIVTRGQYTEKDAARAISDILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLA 601
Query: 184 DFGWS-VHTPSLRRKTMCGTLDYLPPEMIEGRTYDEKVDLWCIGVLCYELLVGYPPFESA 242
DFG S + P ++ T+CGT Y PE+++G Y VD+W +GV+ Y LL GY PF +
Sbjct: 602 DFGLSRIIEPEVQMSTVCGTPGYCAPEVLKGDKYTPSVDMWSVGVIAYILLCGYEPFFAE 781
Query: 243 SHSETYRRILKVDVRFP----LSMPLGARDLISRLLRYQPLERLPLAQILKHPWVQAHSR 298
+ E YR+I+K + +F + A+D++ +LL P +RL + L+ PWV+ +
Sbjct: 782 NEFEMYRKIIKGEYKFDEEYWSEISENAKDVVRKLLVIDPKKRLTATEALRLPWVKGVAT 961
Query: 299 RV 300
+
Sbjct: 962 KT 967
>12721
Length = 821
Score = 115 bits (289), Expect = 2e-26, Method: Compositional matrix adjust.
Identities = 71/236 (30%), Positives = 123/236 (52%), Gaps = 2/236 (0%)
Frame = +1
Query: 18 EELATANQTAQQPSSPAMRRLTVDDFEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKS 77
E+ A Q P P R +DDF +G+G G V +A ++ + K+ +
Sbjct: 37 EQFRAALQMVVTPGDP---RTFLDDF---MKIGEGSTGIVCIATSRDGRQMAVKKMDLRK 198
Query: 78 QIEKEGLEHQLRREIEIQAHLQHPNILRLYNYFHDARRVYLILEYAPRGELYKELQKSEK 137
Q +E L + E+ + HPNI+ +YN + +++++E+ G L ++ + +
Sbjct: 199 QQRRELLFN----EVVVMRDYHHPNIVEMYNSYLVNDELWVVMEFMEGGAL-TDIVTNNR 363
Query: 138 LDEQRTATIIEELADALTYCHDKKVIHRDIKPENLLLGFRGEVKIADFGWSVH-TPSL-R 195
+DE + AT+ AL + H VIHRDIK +++LL G+VK+ DFG+ T L +
Sbjct: 364 MDEVQIATVCRACLKALAFLHANGVIHRDIKSDSILLSHDGKVKLXDFGFCAQVTQDLQK 543
Query: 196 RKTMCGTLDYLPPEMIEGRTYDEKVDLWCIGVLCYELLVGYPPFESASHSETYRRI 251
RK++ GT ++ PE+I Y +VD+W +G++ E++ PPF + + RRI
Sbjct: 544 RKSLVGTPYWMAPEVISRLPYGPEVDIWSLGIMVMEMIDAEPPFFNEPPLQAMRRI 711
>30755
Length = 1137
Score = 110 bits (276), Expect = 5e-25, Method: Compositional matrix adjust.
Identities = 66/177 (37%), Positives = 92/177 (51%), Gaps = 13/177 (7%)
Frame = +2
Query: 140 EQRTATIIEELADALTYCHDKKVIHRDIKPENLLLGFRGEVKIADFGWSVHTPSLRR--K 197
E+RT E+ AL Y H + +I+RD+K ENLLL G +K+ADFG + R K
Sbjct: 29 EERTRFYGAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCKEDITYGRTTK 208
Query: 198 TMCGTLDYLPPEMIEGRTYDEKVDLWCIGVLCYELLVGYPPFESASHSETYRRILKVDVR 257
T CGT +YL PE+++ Y VD W GV+ YE++ G PF + H + IL DV+
Sbjct: 209 TFCGTPEYLAPEVLDDNDYGRAVDWWGTGVVMYEMICGRLPFYNRDHDVLFTLILVEDVK 388
Query: 258 FPLSMPLGARDLISRLLRYQPLERLPLAQ-----ILKHP------WVQAHSRRVLPP 303
FP ++ A+ L+S LL P RL Q I HP W +++ PP
Sbjct: 389 FPRNITDEAKSLLSGLLAKDPRNRLGGGQDDVKEIQAHPFFASINWTDLVQKKITPP 559
>18484
Length = 635
Score = 107 bits (268), Expect = 4e-24, Method: Compositional matrix adjust.
Identities = 63/179 (35%), Positives = 90/179 (50%), Gaps = 3/179 (1%)
Frame = +1
Query: 127 ELYKELQKSEKLDEQRTATIIEELADALTYCHDKKVIHRDIKPENLLLGFRGEVKIADFG 186
+L +Q+ K E A E+A L + HD+ +I+RD+K +N++L G +KIADFG
Sbjct: 1 DLMYRIQQEGKFKEPVAAFYAAEIAVGLFFLHDQGIIYRDLKLDNVMLDSEGHIKIADFG 180
Query: 187 WSVH--TPSLRRKTMCGTLDYLPPEMIEGRTYDEKVDLWCIGVLCYELLVGYPPFESASH 244
T +T CGT DY+ PE++ + Y + VD W GVL +E+L G PPF+
Sbjct: 181 MCKEGMTGDATTRTFCGTPDYIAPEIVLYQPYSKSVDWWAYGVLLFEMLAGQPPFDGEDE 360
Query: 245 SETYRRILKVDVRFPLSMPLGARDLISRLLRYQPLERLPLAQILKHPWVQAHSR-RVLP 302
E + I +V +P +M A L LL P +RL W H R R LP
Sbjct: 361 DELFSSITDHNVSYPKAMSREAVSLCKGLLMKNPTKRLGCGS----KW*TRHQRPRFLP 525
>14420
Length = 528
Score = 107 bits (267), Expect = 5e-24, Method: Compositional matrix adjust.
Identities = 51/152 (33%), Positives = 87/152 (57%), Gaps = 2/152 (1%)
Frame = +2
Query: 90 REIEIQAHLQHPNILRLYNYFHDARRVYLILEYAPRGELYKELQKSEKLDEQRTATIIEE 149
EI + Q+PNI+ + + +++++E+ G L + ++ +DE + A + E
Sbjct: 47 NEILVMRENQNPNIVNYLDSYLVGEELWVVMEFLAGGSLTDVVTET-CMDEGQIAAVCRE 223
Query: 150 LADALTYCHDKKVIHRDIKPENLLLGFRGEVKIADFGWSVHTP--SLRRKTMCGTLDYLP 207
AL + H+ +VIHRDIK +N+LLG G VK+ DFG+ +R TM GT ++
Sbjct: 224 CLQALEFLHENQVIHRDIKSDNILLGMDGSVKLTDFGFCAQLSPEQSKRSTMVGTPYWMA 403
Query: 208 PEMIEGRTYDEKVDLWCIGVLCYELLVGYPPF 239
PE++ + Y VD+W +GV+C E++ G PP+
Sbjct: 404 PEVVTRKQYGPTVDIWSLGVMCIEMIEGEPPY 499
>01707
Length = 757
Score = 105 bits (263), Expect = 2e-23, Method: Compositional matrix adjust.
Identities = 66/195 (33%), Positives = 107/195 (54%), Gaps = 3/195 (1%)
Frame = +1
Query: 44 EIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLRREIEIQAHLQHPNI 103
+IG+ +G+G +G V+ R KE+ +VA+K +S+ + ++ REI + L+HPN+
Sbjct: 76 KIGK-IGEGSYGVVFKCRNKETSQLVAIKKFVESE-DDPLIKKIAMREIRMLKQLKHPNL 249
Query: 104 LRLYNYFHDARRVYLILEYAPRGELYKELQKSEKLDEQRTATIIEELADALTYCHDKKVI 163
+RL F +R++L+ +Y L + + L E II + A+ +CH I
Sbjct: 250 VRLIEVFRRKKRLHLVFDYVDHTLLNELDRYPRGLPEPMVKRIIYQTLLAVNFCHQYNTI 429
Query: 164 HRDIKPENLLLGFRGEVKIADFGWS--VHTPSLRRKTMCGTLDYLPPEMIEGRT-YDEKV 220
HRD+KPEN+L+ +G+VK+ DFG++ + P T Y PE++ G T Y V
Sbjct: 430 HRDVKPENILITRQGQVKLCDFGFARILTGPGDEYTDYVATRWYRAPELLVGDTQYGPPV 609
Query: 221 DLWCIGVLCYELLVG 235
D+W IG + ELL G
Sbjct: 610 DVWAIGCVFAELLTG 654
>18921
Length = 697
Score = 102 bits (253), Expect = 2e-22, Method: Compositional matrix adjust.
Identities = 61/206 (29%), Positives = 108/206 (52%), Gaps = 3/206 (1%)
Frame = +2
Query: 41 DDFEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLRREIEIQAHLQH 100
D F+I LG+G +G+V+ + KE+ ++A+K Q+ + ++ +EI I
Sbjct: 29 DVFDILGKLGEGSYGSVFKSLHKETGQVLAIK-----QVPVDTDLQEIIKEISIMQQCDS 193
Query: 101 PNILRLYNYFHDARRVYLILEYAPRGELYKELQ-KSEKLDEQRTATIIEELADALTYCHD 159
I++ Y + +++++EY G + ++ +++ L E+ ATI+ L Y H
Sbjct: 194 KYIVKYYGSYFKNTDLWIVMEYCGAGSVSDIMRLRNKTLVEREIATILYYTLKGLXYLHS 373
Query: 160 KKVIHRDIKPENLLLGFRGEVKIADFGWS--VHTPSLRRKTMCGTLDYLPPEMIEGRTYD 217
++ IHRDIK N+LL G K+ADFG + + +R T+ GT ++ PE+I+ YD
Sbjct: 374 RRKIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTPYWMAPEVIQEIGYD 553
Query: 218 EKVDLWCIGVLCYELLVGYPPFESAS 243
D+W +G+ E+ G PP S
Sbjct: 554 CVADIWSLGITALEMAEGKPPVMETS 631
>14126
Length = 1265
Score = 101 bits (251), Expect = 4e-22, Method: Compositional matrix adjust.
Identities = 78/262 (29%), Positives = 128/262 (48%), Gaps = 19/262 (7%)
Frame = +3
Query: 12 KAQPAGEELATA----NQTAQQPSSPAMRR---LTVDDFEIGRPLGKGKFGNVYLAR-LK 63
K PA + TA + Q S+ M R T +E +G G +G VY AR L+
Sbjct: 81 KTSPAVRSMKTAISPKGRDGQSESAAKMSRRRDSTEQKYEEVAVIGNGAYGTVYKARDLR 260
Query: 64 ESHFIVALKVLFKSQIEKEGLEHQLRREIEIQAHLQ---HPNILRLYNYFHDAR-----R 115
VA+K + + E EG+ REI + L+ HPN++RL + H+ R
Sbjct: 261 NQGEFVAMKRIRLNNTE-EGMPMMAIREISMLKQLEQYEHPNVVRLLDVSHNTITDREIR 437
Query: 116 VYLILEYAPRGELYKELQK--SEKLDEQRTATIIEELADALTYCHDKKVIHRDIKPENLL 173
+ L+ EY +L L K S L R ++ +L + + + H +++HRD+KP+NLL
Sbjct: 438 LNLVFEYIEH-DLATYLAKCPSPGLGPDRIKDLMLQLLNGVDFLHSNRIVHRDLKPQNLL 614
Query: 174 LGFRGEVKIADFGWS-VHTPSLRRKTMCGTLDYLPPEMIEGRTYDEKVDLWCIGVLCYEL 232
+ G +K+ADFG + +++ + T+ TL Y PE++ Y VD+W G + EL
Sbjct: 615 ISKDGRLKLADFGLARIYSFHMALTTVVVTLWYRSPEVLMQAEYGTSVDIWSCGCIFAEL 794
Query: 233 LVGYPPFESASHSETYRRILKV 254
F+ +S + ++I +V
Sbjct: 795 FTRRALFKGSSEFDQLKKIFEV 860
>01060
Length = 1800
Score = 100 bits (248), Expect = 1e-21, Method: Compositional matrix adjust.
Identities = 76/308 (24%), Positives = 144/308 (46%), Gaps = 40/308 (12%)
Frame = +1
Query: 35 MRRLTVD------DFEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQL 88
++RL +D D + +G+G +G VY R + + +A+K + + + ++G+
Sbjct: 37 IKRLMMDFETALSDLTDFQKIGEGTYGVVYKCRHRATGRKLAMKKI-RLRGSEDGVPSSA 213
Query: 89 RREIEIQAHLQHPNILRLYNYFHDARRVYLILEYAPRG-ELY-KELQKSEKLDEQRTATI 146
REI + L+H NI+ L + + R++L+ E+ ++Y + + LD + +
Sbjct: 214 IREIAMLRELRHTNIVCLEDVIMEDERLFLVFEFLSMDLKMYIDKFPEGVVLDRRLVKSY 393
Query: 147 IEELADALTYCHDKKVIHRDIKPENLLLGFRGEVKIADFGW--SVHTPSLRRKTMCGTLD 204
+ ++ + +CH ++++HRD+KP+NLL+ G +KIADFG + P TL
Sbjct: 394 VFQIVTGIXFCHQRRIVHRDLKPQNLLINHTGAIKIADFGMARTFALPVRAYTHEVVTLW 573
Query: 205 YLPPEMIEGRT-YDEKVDLWCIGVLCYELLVGYPPFESASHSETYRRILKV--------- 254
Y PE++ G + Y VD+W IG + ++L+ P F+ S + +I ++
Sbjct: 574 YRAPEILMGASKYSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTW 753
Query: 255 ---------DVRFPL-----------SMPLGARDLISRLLRYQPLERLPLAQILKHPWVQ 294
+ FPL + DLI R L+ P +R+ ++L+H +
Sbjct: 754 PEFHKLPAFNGMFPLWKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYFL 933
Query: 295 AHSRRVLP 302
V P
Sbjct: 934 NVDTSVKP 957
>09606
Length = 1300
Score = 97.8 bits (242), Expect = 4e-21, Method: Compositional matrix adjust.
Identities = 67/290 (23%), Positives = 126/290 (43%), Gaps = 34/290 (11%)
Frame = -3
Query: 40 VDDFEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLRREIEIQAHLQ 99
+++F + LGKG+ +Y R K + VA+ + K + ++ + + +
Sbjct: 1118 MENFVLYEELGKGEHSIIYKGRRKGTINFVAIHCIEKCK------RPEVTNTVRMTHDIS 957
Query: 100 HPNILRLYNYFHDARRVYLILEYAPRGELYKELQKSEKLDEQRTATIIEELADALTYCHD 159
HPN+++ + ++ + ++L++E G L L + L E L L Y H
Sbjct: 956 HPNVVQFHEWYETSNHLWLVVELCTGGSLADILAQDHHLPETSIRDFGIHLVTGLHYIHS 777
Query: 160 KKVIHRDIKPENLLLGFRGEVKIADFG----------------------WSVHTPS--LR 195
++ D++P +LL G +K ADFG W++ + ++
Sbjct: 776 LGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQWNIQSAEEMMK 597
Query: 196 RKTMCGTLDYLPPEMIEGRTYDEKVDLWCIGVLCYELLVGYPPFESASHSETYRRILKVD 255
+ G+ Y+ PE+ +G DLW +G + YE+ G+PPF ++ T ++L +
Sbjct: 596 QVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSGHPPFLGETYDITKDKVL--N 423
Query: 256 VRFPLSMPLGAR----------DLISRLLRYQPLERLPLAQILKHPWVQA 295
FPL G+R +L+ LL+ RL A ++KH + Q
Sbjct: 422 KEFPLPKVKGSRLSAKPSPEFLNLLESLLQKDSTRRLSWASLVKHAFWQG 273
>00300
Length = 2318
Score = 94.4 bits (233), Expect = 5e-20, Method: Compositional matrix adjust.
Identities = 75/298 (25%), Positives = 136/298 (45%), Gaps = 18/298 (6%)
Frame = -1
Query: 18 EELATANQTAQQPSSPAMR---RLTVDDFEIGRPLGKGKFGNVYLARLKESHFIVALKVL 74
+E + + A +P P R R ++ G +G+G+FG VY A + ++ALK +
Sbjct: 1736 QEKSRIGRVAAKPREPDYRINVRRVNFRWQRGNKIGEGQFGKVYTAVNMSTGELMALKEM 1557
Query: 75 FKSQIEKEGLEHQLRR---EIEIQAHLQHPNILRLYNYFHDARRVYLILEYAPRGELYKE 131
+ + L+ QLR EI+I +QH N+++ Y + + +EY G + E
Sbjct: 1556 ---KFQPNDLQ-QLREMCDEIKIFEGIQHENLVKYYGVEVHKDEMLMFMEYCDTGTI--E 1395
Query: 132 LQKSEKLDEQRTATIIEELADALTYCHDKKVIHRDIKPENLLLGFRGEVKIADFGWSVHT 191
L E E+ A+ + H+ ++HRDIK N+ L G VK+ DFG SV
Sbjct: 1394 EAAKMGLPEYLIRRYTREIVLAVNHLHENSIVHRDIKGANIFLTSNGHVKLGDFGCSVKL 1215
Query: 192 PSLRR-----KTMCGTLDYLPPEMI---EGRTYDEKVDLWCIGVLCYELLVGYPPFESAS 243
S + GT Y+ PE+ + Y D+W +G + E+ G P+
Sbjct: 1214 KSHTTMPGEFHNLVGTTAYMAPEVFTQNDQGGYGRAADIWSLGCVVIEMATGKRPWHDLD 1035
Query: 244 HSETYRRILKVDV----RFPLSMPLGARDLISRLLRYQPLERLPLAQILKHPWVQAHS 297
++ Y+ + KV + P S+ + + + ++ + P +R +Q+L H + + ++
Sbjct: 1034 NN--YQIMYKVGIGHKPAVPDSLSVEGKHFLDLIMCHDPAQRALASQLLDHTFTKVYN 867
>01392
Length = 1806
Score = 92.0 bits (227), Expect = 2e-19, Method: Compositional matrix adjust.
Identities = 65/209 (31%), Positives = 99/209 (47%), Gaps = 37/209 (17%)
Frame = -1
Query: 138 LDEQRTATIIEELADALTYCHDKKVIHRDIKPENLLLGFRGEV---KIADF--------- 185
L E+ + ++ +A AL + H K + HRD+KPEN+L +V KI DF
Sbjct: 1800 LCEREASLVVRHIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGISCD 1621
Query: 186 GWSVHTPSLRRKTMCGTLDYLPPEMIEGR-----TYDEKVDLWCIGVLCYELLVGYPPFE 240
G TP L T G+ +Y+ PE+++ +YD++ DLW +G++ Y +L GYPPF
Sbjct: 1620 GDGTKTPELL--TPVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILYIMLCGYPPFY 1447
Query: 241 SASHSET---------------YRRILKVDVRFP----LSMPLGARDLISRLLRYQPLER 281
+ + I +FP S+ A+DLI LL +P +R
Sbjct: 1446 GQCGEDCGWNRGEACHDCQDMLFNSIQDGHYKFPSQEWTSISSSAKDLIRHLLVREPRKR 1267
Query: 282 LPLAQILKHPWVQAHSRRVLPPCA-QMAS 309
A +LKHPW+ PP A Q+A+
Sbjct: 1266 YSAADVLKHPWI------CTPPAATQLAT 1198
>13066
Length = 551
Score = 88.2 bits (217), Expect = 4e-18, Method: Compositional matrix adjust.
Identities = 52/181 (28%), Positives = 92/181 (50%), Gaps = 6/181 (3%)
Frame = +3
Query: 52 GKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLRREIEIQAHLQHPNILRLYNYFH 111
G F + Y +K +A K++ K + + +E RE+++ L HP I+++++
Sbjct: 24 GTFNDGYGRNIK-----LACKIIDKEKAPVDFVEKFFPRELDLLTKLDHPYIIQIHSILQ 188
Query: 112 DARRVYLILEYAPRGELYKELQKSEKLDEQRTATIIEELADALTYCHDKKVIHRDIKPEN 171
+ ++ + +A RG+L +Q+ + E++ ++ AL Y H V HRD+K EN
Sbjct: 189 RXPKNFIFMRFAERGDLLTYIQEVGFVKEKQAKIWFYQMTTALNYLHSYDVAHRDLKCEN 368
Query: 172 LLLGFRGEVKIADFGWSVHTPS-----LRRKTMCGTLDYLPPEMIEGRTYDEKV-DLWCI 225
+LL VK+ADFG++ + +T CG+ Y PE++ G Y KV D W +
Sbjct: 369 ILLSSHFNVKLADFGFACACITESGEKYMSRTYCGSAAYAAPEIVYGAPYAPKVADAWSL 548
Query: 226 G 226
G
Sbjct: 549 G 551
>06405
Length = 1965
Score = 88.2 bits (217), Expect = 4e-18, Method: Compositional matrix adjust.
Identities = 70/266 (26%), Positives = 116/266 (43%), Gaps = 10/266 (3%)
Frame = +1
Query: 32 SPAMRRLTVDDFEIGRP--LGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLR 89
SP R ++ EI LG G++G+VY A K + IVA+K L + + +
Sbjct: 226 SPEPDRWEIERTEIAMKHRLGGGQYGDVYEAMWKRYNKIVAVKTLKEDTMAL----NDFL 393
Query: 90 REIEIQAHLQHPNILRLYNYFHDARRVYLILEYAPRGELYKELQKSEKLDEQRTATI--I 147
E I ++HPN+++L Y++ E+ P G L L+ S + + TA +
Sbjct: 394 EEAAIMKEMKHPNLVQLLGVCTREPPFYIVTEFMPHGNLLDYLRSSTREENGPTALMYMA 573
Query: 148 EELADALTYCHDKKVIHRDIKPENLLLGFRGEVKIADFGWSVHTPSLRRKTMCGT---LD 204
++A + Y K IHRD+ N L+ VK+ADFG + G +
Sbjct: 574 TQIASGMAYLETKNFIHRDLAARNCLVADSNMVKVADFGLARLMKDDTYTAHIGAKFPIK 753
Query: 205 YLPPEMIEGRTYDEKVDLWCIGVLCYELLV-GYPPFESASHSETYRRILKVDVRF--PLS 261
+ PE + + + D+W GVL +EL G P+ +E Y +L+ R P
Sbjct: 754 WTAPEGLAFNRFSTRSDIWAFGVLLWELATYGMSPYPGVELTEVY-HLLERGYRMERPPG 930
Query: 262 MPLGARDLISRLLRYQPLERLPLAQI 287
P L+ + ++ P +R +I
Sbjct: 931 TPADVYILMLKCWQWDPKDRPTFKEI 1008
>01756
Length = 1858
Score = 88.2 bits (217), Expect = 4e-18, Method: Compositional matrix adjust.
Identities = 71/257 (27%), Positives = 116/257 (45%), Gaps = 29/257 (11%)
Frame = -3
Query: 49 LGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLRREIEIQAHLQHPNILRLYN 108
+G+G FG V+ AR K++ +VA+K + EKEG REI+I L H N++ L
Sbjct: 1718 IGQGTFGEVFKARCKKTKQVVAMKKVLMDN-EKEGFPITALREIKILQLLNHENVVDLIE 1542
Query: 109 YFH----DARR----VYLILEYAPRGELYKELQKSEKLDEQRTATIIEELADALTYCHDK 160
A R YL+ E+ S + ++++L + L Y H
Sbjct: 1541 ICSTKATSANRYKSMFYLVFEFCEHDLAGLLSNMSVVFNLPEIKEVMKQLMNGLYYIHRN 1362
Query: 161 KVIHRDIKPENLLLGFRGEVKIADFG----WSVHTPSLRRKTM-CGTLDYLPPEMIEG-R 214
K++HRD+K N+L+ +G +K+ADFG +SV+ R T TL Y PPE++ G R
Sbjct: 1361 KILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRPPELLLGDR 1182
Query: 215 TYDEKVDLWCIGVLCYELLVGYPPFESASHS---------------ETYRRILKVDVRFP 259
Y +D W G + E+ P + + E + + ++++
Sbjct: 1181 NYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQNQLTLITQLCGSITPEVWPGVERLELYNS 1002
Query: 260 LSMPLGARDLISRLLRY 276
L +P G + + LRY
Sbjct: 1001 LDLPQGNKRKVKERLRY 951
>21079
Length = 878
Score = 87.0 bits (214), Expect = 9e-18, Method: Compositional matrix adjust.
Identities = 43/143 (30%), Positives = 79/143 (55%), Gaps = 4/143 (2%)
Frame = +1
Query: 100 HPNILRLYNYFHDARRVYLILEYAPRGELYKELQKSE-KLDEQRTATIIEELADALTYCH 158
HP +L L++ F R + L++E+ GEL++ + + + L E+ + ++ + Y H
Sbjct: 1 HPKLLMLWDAFEAPRTMVLVMEFVGAGELFERVIRDDFVLTERDCVHFVRQICSGVGYMH 180
Query: 159 DKKVIHRDIKPENLLL--GFRGEVKIADFGWS-VHTPSLRRKTMCGTLDYLPPEMIEGRT 215
+ ++H D+KPEN+L ++KI DFG + + P + + GT +++ PE++
Sbjct: 181 TQSILHLDLKPENVLCVSDNSNQIKIIDFGLARFYKPGDSLQVLFGTPEFIAPEVVNYDE 360
Query: 216 YDEKVDLWCIGVLCYELLVGYPP 238
+ D+W IGV+CY LL G P
Sbjct: 361 INFTTDMWSIGVICYILLSGLSP 429
>09007
Length = 1440
Score = 85.1 bits (209), Expect = 3e-17, Method: Compositional matrix adjust.
Identities = 70/259 (27%), Positives = 116/259 (44%), Gaps = 24/259 (9%)
Frame = -1
Query: 5 RAVVQLGKAQPAGEELATA--NQTAQQPSSPAMR------RLTVDDFEIGRPLGKGKFGN 56
RA+++ G +P G L+ + +P S +R ++ D + + LG+G FG
Sbjct: 1008 RAIMRSGGGEP-GRSLSPSPPEHRMSRPVSAVVRPARGKQLISKDCVALSKSLGQGHFGT 832
Query: 57 V----YLARLKESHFIVALKVLFKSQIEKEGLEHQLRREIEIQAHLQHPNILRLYNYFHD 112
V + A E VA+K L K +I K+G E +E I L H NI+R+Y D
Sbjct: 831 VRQAIWTAESGEK-VQVAVKCLSKDKIHKDGQE--FLKETAIMQMLDHENIVRVYGVVMD 661
Query: 113 -ARRVYLILEYAPRG---ELYKELQKSEKLDEQRTATIIEELADALTYCHDKKVIHRDIK 168
+ L+ E AP E KE+ R +++ D ++Y K+++HRD+
Sbjct: 660 NGADIMLVTELAPMRSLLECVKEVSARVDFSVPRLCDFSQQVCDGMSYLESKRLVHRDLA 481
Query: 169 PENLLLGFRGEVKIADFGWSV-------HTPSLRRKTMCGTLDYLPPEMIEGRTYDEKVD 221
N+LL + +VKI+D G S + S + + + + PE + D
Sbjct: 480 ARNILLFSKSKVKISDVGVSGALGAGKEYYQSQQTIHLQNAVAWCAPESFRNLCFSSASD 301
Query: 222 LWCIGVLCYELLV-GYPPF 239
+W GVL +E G+ P+
Sbjct: 300 VWAFGVLLWEFFTHGFQPW 244
>27546
Length = 426
Score = 83.6 bits (205), Expect = 9e-17, Method: Compositional matrix adjust.
Identities = 40/120 (33%), Positives = 74/120 (61%)
Frame = -1
Query: 69 VALKVLFKSQIEKEGLEHQLRREIEIQAHLQHPNILRLYNYFHDARRVYLILEYAPRGEL 128
+A K++ K++ + ++ RE+EI L HPNI+++++ ++++ + YA +G++
Sbjct: 396 LACKIIDKAKAPIDFVKKFFPRELEILTRLDHPNIIQIHSILQRGPKIFIFMRYAEKGDM 217
Query: 129 YKELQKSEKLDEQRTATIIEELADALTYCHDKKVIHRDIKPENLLLGFRGEVKIADFGWS 188
++K+ +DE +T ++A AL Y H + HRD+K EN+LL R VKIADFG++
Sbjct: 216 LSHIKKTGPIDEAQTKVWFFQMAKALQYLHSHDIAHRDLKCENILLSKRLNVKIADFGFA 37
>17975
Length = 449
Score = 83.6 bits (205), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 49/137 (35%), Positives = 82/137 (59%), Gaps = 2/137 (1%)
Frame = +3
Query: 54 FGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLRREIEIQAHLQHPNILRLYNYFHDA 113
F V LAR + VA+KV+ K+++++ H L +E+ +QHPN++RLY
Sbjct: 6 FAVVKLARHVFTGEKVAVKVIDKTKLDEVSRSH-LFQEVRCMKLVQHPNVVRLYEVIDTQ 182
Query: 114 RRVYLILEYAPRGELYKELQK-SEKLDEQRTATIIEELADALTYCHDKKVIHRDIKPENL 172
++YLILE G++Y + + S L+E+ ++ +A++YCH V+HRD+KPEN+
Sbjct: 183 TKLYLILELGDGGDMYDYIMRHSGGLEEKLAKRYFRQIVEAISYCHKLHVVHRDLKPENV 362
Query: 173 LLGFR-GEVKIADFGWS 188
+ + G VK+ DFG+S
Sbjct: 363 VFFEKPGLVKLTDFGFS 413
>01718
Length = 959
Score = 83.2 bits (204), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 64/214 (29%), Positives = 101/214 (47%), Gaps = 10/214 (4%)
Frame = +3
Query: 34 AMRRLTVDDFEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLRREIE 93
A+ RL DDF I +G G F V+ K +H I + K H + RE++
Sbjct: 135 ALTRL--DDF-ICEKIGAGFFSEVF----KVTHRITGQVMALKMNTMTSN-RHNMLREVQ 290
Query: 94 IQAHLQHPNILRLYNYFHDARRVYLILEYAPRGELYKELQ-KSEKLDEQRTATIIEELAD 152
+ LQH NILR +++ + EY P G L + L+ K E+L + + LA
Sbjct: 291 LLNRLQHANILRFMGVCVHEGQLHALTEYIPSGNLEQLLEKKDEELPWTQRIQLTLGLAR 470
Query: 153 ALTYCHDKKVIHRDIKPENLLL------GFRGEVKIADFGWSVHTPSLRRKT---MCGTL 203
L Y H + IHRD+ +N+L+ G+ IADFG + P K G+
Sbjct: 471 GLDYLHSTRFIHRDLTSKNILIRREDNHGYHA--VIADFGLATKIPDPLDKEKLPTVGSP 644
Query: 204 DYLPPEMIEGRTYDEKVDLWCIGVLCYELLVGYP 237
++ PE++ G Y+E+ DL+ +G++ E+ P
Sbjct: 645 YWMAPEVLNGHFYNERADLFSVGIIMCEITARIP 746
>00392
Length = 668
Score = 81.3 bits (199), Expect = 4e-16, Method: Compositional matrix adjust.
Identities = 54/174 (31%), Positives = 92/174 (52%), Gaps = 9/174 (5%)
Frame = +3
Query: 87 QLRREIEIQAHLQHPNILRLYNYF----HDARRV-YLILEYAPRGELYKELQKSEKLDEQ 141
+ + E E+ LQHPNI+R ++Y+ H R+V L+ E G L L++ +K + +
Sbjct: 69 RFKEEAEMLKELQHPNIVRFFDYWEEHNHRNRKVIILVTELMTSGTLKTYLKRFKKPNVK 248
Query: 142 RTATIIEELADALTYCHDKK--VIHRDIKPENLLL-GFRGEVKIADFGWSVHTPSLRRKT 198
++ L + H + VIHRD+K +N+ + G G VKI D G + K+
Sbjct: 249 ILKNWCRQVLKGLYFLHTRTPPVIHRDLKCDNIFITGPTGSVKIGDLGLATLKNQSFAKS 428
Query: 199 MCGTLDYLPPEMIEGRTYDEKVDLWCIGVLCYELLVG-YPPFESASHSETYRRI 251
+ GT +++ PEM E YDE VD++ G+ E+ YP E ++ ++ Y+R+
Sbjct: 429 VIGTPEFMAPEMYEEH-YDEAVDVYAFGMCMLEMASSEYPYSECSNAAQIYKRV 587
>04591
Length = 1117
Score = 80.9 bits (198), Expect = 5e-16, Method: Compositional matrix adjust.
Identities = 72/261 (27%), Positives = 114/261 (43%), Gaps = 48/261 (18%)
Frame = -2
Query: 81 KEGLEHQLRREIEIQAHLQHPNILRLYNYFHD--------ARRVYLILEYAPR--GELYK 130
KEG REI+I L+H N+++L H YLI EY L
Sbjct: 1101 KEGFPITALREIKILQQLEHENVVQLQEICHTQAGPYNRYKSTFYLIFEYCDYDLAGLLN 922
Query: 131 ELQKSEKLDEQRTATIIEELADALTYCHDKKVIHRDIKPENLLLGFRGEVKIADFGWSVH 190
L+ L +++ ++ +L + L Y H K+++HRDIK N+LL G +K+ADFG S
Sbjct: 921 NLRVKFSLADKKN--LMSQLLNGLFYIHTKQILHRDIKAANILLTRDGVLKLADFGLS-- 754
Query: 191 TPSLRRKTMCG---TLDYLPPEMIEG-RTYDEKVDLWCIGVLCYELLVGYPPFESAS--- 243
P ++ K + TL Y PPE++ G R Y ++D+W +G + E+ P + S
Sbjct: 753 RPWVKSKRLTNRVVTLWYRPPELLLGEREYGPEIDMWGVGCIMAEMWSRKPLMQGRSEQH 574
Query: 244 ------------HSETYRRILKVDVRFPLSMPLG-----------------ARDLISRLL 274
++E + + K+++ L +P G +LI L
Sbjct: 573 QLSLITDLCGSLNAEVWPGVTKLELYGKLDLPQGKPRKVKERMLDLLKNKEGAELIDIFL 394
Query: 275 RYQPLERLPLAQILKHP--WV 293
R P +R+ L H WV
Sbjct: 393 RLDPGQRMNCDNALSHDFFWV 331
>13592
Length = 980
Score = 80.5 bits (197), Expect = 8e-16, Method: Compositional matrix adjust.
Identities = 61/260 (23%), Positives = 117/260 (45%), Gaps = 13/260 (5%)
Frame = +2
Query: 49 LGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLRREIEIQAHLQHPNILRLYN 108
+G+G+FG VY A + ++A+K + E L++ + E++I ++H N++R Y
Sbjct: 8 IGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETRALKN-VAEELKILEGIKHKNLVRYYG 184
Query: 109 YFHDARRVYLILEYAPRGELYKELQKSEKLDEQRTATIIEELADALTYCHDKKVIHRDIK 168
+ + +E G L ++ + L E + +L + H ++HRDIK
Sbjct: 185 IEVHREELLIFMELCSEGTLESLVELTGGLPEALSRRFTAQLLSGVAELHKHGIVHRDIK 364
Query: 169 PENL-LLGFRGEVKIADFGWSVH-----TPSLRRKTMCGTLDYLPPEMIEGRTYDEK--- 219
N+ L+ +K+ DFG +V T + GT Y+ PE+ D
Sbjct: 365 TANIFLVDGSNSLKLGDFGSAVKIQAHTTVPGELQGYVGTQAYMAPEVFTKTNSDGHGRL 544
Query: 220 VDLWCIGVLCYELLVGYPPFESASHSETYRRILKVDV----RFPLSMPLGARDLISRLLR 275
D+W +G + E+ G P+ A ++ + KV + + P S+ D I L+
Sbjct: 545 ADIWSVGCVVVEMASGKRPW--AQFDSNFQIMFKVGMGEKPQAPESLSQEGHDFIDHCLQ 718
Query: 276 YQPLERLPLAQILKHPWVQA 295
+ P +RL ++L+ + ++
Sbjct: 719 HDPKQRLSAIELLEQNFCKS 778
>31885
Length = 529
Score = 77.8 bits (190), Expect = 5e-15, Method: Compositional matrix adjust.
Identities = 49/163 (30%), Positives = 79/163 (48%), Gaps = 6/163 (3%)
Frame = -2
Query: 91 EIEIQAHLQHPNILRLYNYFHDARRVYLILEYAPRGELYKELQKSEKLDEQRTATIIEEL 150
+++ L HP ++ L+ F D ++++++ G+L +Q+ E + +L
Sbjct: 522 NVDMLTRLDHPFLVNLWYAFQDEEDLFMVVDLFLGGDLRYHMQQEVSFREDCVKFYLCQL 343
Query: 151 ADALTYCHDKKVIHRDIKPENLLLGFRGEVKIADFGWSVHTPSLRRKT-MCGTLDYLPPE 209
A L Y +K++HRDIKP+N+LL +G + DF + T GT Y+ PE
Sbjct: 342 ALVLDYLRSQKIVHRDIKPDNILLDEQGHCHVTDFNIATQLEDDELATSTSGTRPYMAPE 163
Query: 210 MI-----EGRTYDEKVDLWCIGVLCYELLVGYPPFESASHSET 247
+ E R Y VD W +GV +ELL PF + HS T
Sbjct: 162 VYGVAINERRGYGFPVDWWSLGVSLFELLKKRRPF--SVHSNT 40
>13212
Length = 1067
Score = 77.4 bits (189), Expect = 6e-15, Method: Compositional matrix adjust.
Identities = 58/189 (30%), Positives = 90/189 (47%), Gaps = 10/189 (5%)
Frame = -1
Query: 116 VYLILEYAPRGELYKELQKSEKLDEQRTATIIEELADALTYCHDKKVIHRDIKPENLLLG 175
V+ +L + + +L+K + E + + E+ AL + H VIHRDIK N+LL
Sbjct: 1049 VFRVLWWGALDSIMVDLEKP--MTEAQICYVCHEMCMALDFLHRHHVIHRDIKAGNVLLT 876
Query: 176 FRGEVKIADFGWSVHTPSL--RRKTMCGTLDYLPPEMIEGRT-----YDEKVDLWCIGVL 228
GEVK+ADFG S +R T GT ++ PE++ T YD K D+W +GV
Sbjct: 875 IDGEVKLADFGVSAKNTQTQQKRDTFIGTPYWMAPEVVLCETLKDTPYDFKADIWSLGVT 696
Query: 229 CYELLVGYPPFESASHSETYRRILKVD---VRFPLSMPLGARDLISRLLRYQPLERLPLA 285
E PP + +I K D + P +D I++ L P R A
Sbjct: 695 LIEFAQIEPPNKEMHPMRVLIKIHKSDPPTLEKPKKWTKLFKDFIAKCLVKDPNLRPTAA 516
Query: 286 QILKHPWVQ 294
++L+HP+++
Sbjct: 515 ELLEHPFMK 489
>00486
Length = 797
Score = 74.3 bits (181), Expect = 5e-14, Method: Compositional matrix adjust.
Identities = 34/85 (40%), Positives = 51/85 (60%)
Frame = -2
Query: 198 TMCGTLDYLPPEMIEGRTYDEKVDLWCIGVLCYELLVGYPPFESASHSETYRRILKVDVR 257
T CGT++Y+ PE++ + + VD W +G L Y++L G PPF + + +T +ILK +
Sbjct: 781 TFCGTIEYMAPEILTRTGHGKAVDWWSLGALMYDMLTGSPPFTAENRKKTIDKILKGKLN 602
Query: 258 FPLSMPLGARDLISRLLRYQPLERL 282
P + AR LI +LLR P ERL
Sbjct: 601 LPPYLTNEARGLIKKLLRKNPAERL 527
>26560
Length = 398
Score = 72.0 bits (175), Expect = 3e-13, Method: Compositional matrix adjust.
Identities = 39/126 (30%), Positives = 65/126 (51%), Gaps = 1/126 (0%)
Frame = -1
Query: 127 ELYKELQKSEKLDEQRTATIIEELADALTYCHDKKVIHRDIKPENLLLGFRGEVKIADFG 186
+L+ L + E+ E+ L + H + V++RD+KP N+LL G V+I+D G
Sbjct: 398 DLHYHLSQHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLG 219
Query: 187 WSVHTPSLRRKTMCGTLDYLPPE-MIEGRTYDEKVDLWCIGVLCYELLVGYPPFESASHS 245
+ R GT Y+ PE +++G++YD D + G + Y+LL G+ PF H+
Sbjct: 218 LACDFSKKRPHASVGTHGYMAPEVLMKGQSYDSSADWFSFGCMLYKLLKGHSPFR--QHN 45
Query: 246 ETYRRI 251
+ RI
Sbjct: 44 QGQARI 27
>25019
Length = 730
Score = 48.5 bits (114), Expect(2) = 3e-13, Method: Compositional matrix adjust.
Identities = 26/63 (41%), Positives = 35/63 (55%), Gaps = 3/63 (4%)
Frame = +1
Query: 223 WCIGV---LCYELLVGYPPFESASHSETYRRILKVDVRFPLSMPLGARDLISRLLRYQPL 279
W GV L Y++L G PPF + + +T +ILK + P + AR LI +LLR P
Sbjct: 418 WTGGVWGALMYDMLTGSPPFTAENRKKTIDKILKGKLNLPPYLTNEARGLIKKLLRKNPA 597
Query: 280 ERL 282
ERL
Sbjct: 598 ERL 606
Score = 43.5 bits (101), Expect(2) = 3e-13, Method: Compositional matrix adjust.
Identities = 22/59 (37%), Positives = 33/59 (55%), Gaps = 2/59 (3%)
Frame = +3
Query: 170 ENLLLGFRGEVKIADFGWSVHTPSLRR--KTMCGTLDYLPPEMIEGRTYDEKVDLWCIG 226
EN+LL G VK+ DFG + R T CGT++Y+ PE++ + + VD W +G
Sbjct: 261 ENVLLDKDGHVKLTDFGLCKEAITGTRVTHTFCGTIEYMAPEILTRTGHGKAVDWWSLG 437
>20152
Length = 445
Score = 70.9 bits (172), Expect = 6e-13, Method: Compositional matrix adjust.
Identities = 34/88 (38%), Positives = 54/88 (61%), Gaps = 1/88 (1%)
Frame = +1
Query: 208 PEMIEGRTYDE-KVDLWCIGVLCYELLVGYPPFESASHSETYRRILKVDVRFPLSMPLGA 266
PE++ G +YD VD+W +GV+ Y L+VG PF+ A+ SET I+ + P +
Sbjct: 1 PEILLGDSYDAPAVDVWSLGVILYMLVVGEAPFQEANDSETLTMIMDCRYQIPPHISHKC 180
Query: 267 RDLISRLLRYQPLERLPLAQILKHPWVQ 294
+DLI ++L+ +P++R L IL HPW+
Sbjct: 181 QDLIEKMLQREPVDRASLPHILAHPWLN 264
>18663
Length = 600
Score = 70.9 bits (172), Expect = 7e-13, Method: Compositional matrix adjust.
Identities = 41/128 (32%), Positives = 60/128 (46%), Gaps = 21/128 (16%)
Frame = +2
Query: 197 KTMCGTLDYLPPEMIEGRTYDEKVDLWCIGVLCYELLVGYPPFESASHSET--------- 247
T CGT +Y+ PE++ G Y VD W +GVL YE+L G PF+ A SE
Sbjct: 2 STFCGTPNYIAPEILRGEDYGFSVDWWALGVLLYEMLAGRSPFDIAGASENPDQNTEDYL 181
Query: 248 YRRILKVDVRFPLSMPLGARDLISRLLRYQPLERL------PLAQILKHP------WVQA 295
++ IL+ +R P S+ + A ++ L P +RL I+ HP W
Sbjct: 182 FQVILEKTIRIPRSLSVKAASVLKGFLNKNPADRLGCHRESAFMDIVNHPFFKVIDWEML 361
Query: 296 HSRRVLPP 303
++V PP
Sbjct: 362 ERKQVSPP 385
>01966
Length = 1735
Score = 70.5 bits (171), Expect = 7e-13, Method: Compositional matrix adjust.
Identities = 39/138 (28%), Positives = 73/138 (52%), Gaps = 4/138 (2%)
Frame = -1
Query: 80 EKEGLEHQLRREIEIQAHLQHPNILRLYNYFHDARRVYLILEYAPRG-ELY-KELQKSEK 137
++G+ REI + L+H NI+ L + + R++L+ E+ ++Y + +
Sbjct: 1597 SEDGVPSSAIREIAMLRELRHTNIVCLEDVIMEDERLFLVFEFLSMDLKMYIDKFPEGVV 1418
Query: 138 LDEQRTATIIEELADALTYCHDKKVIHRDIKPENLLLGFRGEVKIADFGW--SVHTPSLR 195
LD + + + ++ + +CH ++++HRD+KP+NLL+ G +KIADFG + P
Sbjct: 1417 LDRRLVKSYVFQIVTGINFCHQRRIVHRDLKPQNLLINHTGAIKIADFGMARTFALPVRA 1238
Query: 196 RKTMCGTLDYLPPEMIEG 213
TL Y PE++ G
Sbjct: 1237 YTHEVVTLWYRAPEILMG 1184
>19301
Length = 712
Score = 69.7 bits (169), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 47/140 (33%), Positives = 70/140 (50%)
Frame = +2
Query: 49 LGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLRREIEIQAHLQHPNILRLYN 108
LG G G V+L +L VA+K K + KE LR+ L HPNI+
Sbjct: 329 LGSGAQGAVFLGKLCAEE--VAVK---KVRDIKETDIRNLRK-------LNHPNIISFKG 472
Query: 109 YFHDARRVYLILEYAPRGELYKELQKSEKLDEQRTATIIEELADALTYCHDKKVIHRDIK 168
A +I+EY P G+LY+ L+ +++ +++A + Y H K+IHRD+K
Sbjct: 473 VCTQAPCYCIIMEYCPYGQLYEVLRDGKEIPPALVLDWSKQIASGMNYLHSHKIIHRDLK 652
Query: 169 PENLLLGFRGEVKIADFGWS 188
N+L+ VKI+DFG S
Sbjct: 653 SPNVLVAKNDVVKISDFGTS 712
>19094
Length = 898
Score = 69.3 bits (168), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 38/111 (34%), Positives = 61/111 (54%), Gaps = 2/111 (1%)
Frame = +1
Query: 134 KSEKLDEQRTATIIEELADALTYCHDKKVIHRDIKPENLLLGFRGEVKIADFGWS--VHT 191
+++ L E+ ATI+ L Y H ++ IHRDIK N+LL G K+ADFG + +
Sbjct: 37 RNKTLVEREIATILYYTLKGL*YLHSRRKIHRDIKAGNILLNNEGHAKLADFGVAGQLTD 216
Query: 192 PSLRRKTMCGTLDYLPPEMIEGRTYDEKVDLWCIGVLCYELLVGYPPFESA 242
+R T+ GT ++ PE+I+ YD D+W +G+ E+ G E++
Sbjct: 217 TMAKRNTVIGTPYWMAPEVIQEIGYDCVADIWSLGITALEMAEGNLHMETS 369
>27405
Length = 532
Score = 68.2 bits (165), Expect = 4e-12, Method: Compositional matrix adjust.
Identities = 48/175 (27%), Positives = 82/175 (46%), Gaps = 5/175 (2%)
Frame = -3
Query: 54 FGNVYLARLKESHFIVALKVLFKSQIEKEGLEH-QLRREIE---IQAHLQHPNILRLYNY 109
FG VY R ++ + A+K L K +I+ +G E L I + P I+ +
Sbjct: 527 FGEVYGCRKADTGKMYAMKCLDKKRIKMKGGETLALNERIMLSLVSTGEGSPFIVCMTYA 348
Query: 110 FHDARRVYLILEYAPRGELYKELQKSEKLDEQRTATIIEELADALTYCHDKKVIHRDIKP 169
F ++ IL+ G+L+ L + E+ E+ L + H + V++RD+KP
Sbjct: 347 FQTPEKLCFILDLMNGGDLHYHLSQHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKP 168
Query: 170 ENLLLGFRGEVKIADFGWSVHTPSLRRKTMCGTLDYLPPE-MIEGRTYDEKVDLW 223
N+LL G V+I+D G + + GT Y+ PE +++G+ YD D +
Sbjct: 167 ANILLDENGHVRISDLGLACDFSKKKPHASVGTHGYMAPEVLMKGQAYDSSADWF 3
>11780
Length = 1713
Score = 65.5 bits (158), Expect(2) = 2e-11, Method: Compositional matrix adjust.
Identities = 39/147 (26%), Positives = 71/147 (48%), Gaps = 2/147 (1%)
Frame = +3
Query: 42 DFEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLRREIEIQAHLQHP 101
D EIG +GKG FG+VY + V K +K+ E +E + L+H
Sbjct: 600 DLEIGEAIGKGDFGDVYKGMYR------GQPVAIKQLKDKDRGEQSFLQEASVMTSLRHD 761
Query: 102 NILRLYNYFHDARRVYLILEYAPRGELYKELQKSEK--LDEQRTATIIEELADALTYCHD 159
N++RL ++L+ E+ +G L + L+ + + ++ + A+ Y
Sbjct: 762 NLVRLIGVVL-GETIFLVTEFMGKGNLVEYLRSRGRSVITKKDQINFATDTCAAMEYLES 938
Query: 160 KKVIHRDIKPENLLLGFRGEVKIADFG 186
K+++HRD+ N+L+ G+ K++DFG
Sbjct: 939 KRLVHRDLAARNVLVHDDGKAKVSDFG 1019
Score = 20.8 bits (42), Expect(2) = 2e-11, Method: Compositional matrix adjust.
Identities = 6/17 (35%), Positives = 11/17 (64%)
Frame = +1
Query: 216 YDEKVDLWCIGVLCYEL 232
+ K D+W G+L +E+
Sbjct: 1105 FTSKSDMWSFGILLWEI 1155
>26711
Length = 405
Score = 65.9 bits (159), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 40/133 (30%), Positives = 67/133 (50%), Gaps = 8/133 (6%)
Frame = -2
Query: 146 IIEELADALTYCHDKKVIHRDIKPENLLLGFR--GEVKIADFGWSVHT-PSLRRKTMCGT 202
+++++ D L + H + V+H D+KP NLLL V++ DFG + P GT
Sbjct: 401 VVKQVLDILQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARKLYPPQETFLNHGT 222
Query: 203 LDYLPPEMIEGRTYDEKVDLWCIGVLCYELLVGYPPFESASHSETYRRILKVDVRFPL-- 260
+ PE ++ + D+W +GVL Y LL G PF++ S +E+ ++ D F +
Sbjct: 221 PGFTSPEALDVKPISTASDVWGVGVLAYILLSGQSPFQADSATESLKKTQTCDWSFDVCP 42
Query: 261 ---SMPLGARDLI 270
+M A+D I
Sbjct: 41 SFSNMSQDAKDFI 3
>29581
Length = 1278
Score = 65.1 bits (157), Expect = 4e-11, Method: Compositional matrix adjust.
Identities = 46/148 (31%), Positives = 73/148 (49%), Gaps = 5/148 (3%)
Frame = -2
Query: 97 HLQHPNILRLYNYF--HDARRVYLILEYAPRGELYKELQKSEKLDEQRTATIIEELADAL 154
+L+H NI++L ++L++EY + E + I+ +L L
Sbjct: 1187 NLRHQNIVQLQEVVVGKSLDSLFLVMEYCEQDLASLLDNMPAPFSESQVKCIVLQLLKGL 1008
Query: 155 TYCHDKKVIHRDIKPENLLLGFRGEVKIADFGWSVH--TPSLRRKTMCGTLDYLPPEMIE 212
Y H+ +IHRD+K NLL+ +G VKIADFG + + P TL Y PE++
Sbjct: 1007 RYLHEAFIIHRDLKVSNLLMTDKGCVKIADFGLARNYGKPQKPMTPKVVTLWYRAPELLF 828
Query: 213 G-RTYDEKVDLWCIGVLCYELLVGYPPF 239
G +T+ +D+W G + ELL G+ P
Sbjct: 827 GSKTHSTAIDMWSAGCILGELL-GHKPL 747
>14477
Length = 493
Score = 63.2 bits (152), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 44/142 (30%), Positives = 74/142 (52%), Gaps = 2/142 (1%)
Frame = -1
Query: 49 LGKGKFGNVY--LARLKESHFIVALKVLFKSQIEKEGLEHQLRREIEIQAHLQHPNILRL 106
LG G FG+V + RL + VA+KVL + ++ ++ +L +E E+ + H +I+RL
Sbjct: 466 LGAGNFGSVMKGVCRLDDREIPVAIKVLKNADLDP-SVQSELIKEAEVMKKMDHMHIVRL 290
Query: 107 YNYFHDARRVYLILEYAPRGELYKELQKSEKLDEQRTATIIEELADALTYCHDKKVIHRD 166
+ + L+LE A G L K L K++ L ++ +++ + Y K +HRD
Sbjct: 289 IG-LCEGETMMLVLELAKLGPLNKFLPKNKHLPLWNILELMWQVSQGMEYLEANKFVHRD 113
Query: 167 IKPENLLLGFRGEVKIADFGWS 188
+ N+LL KI+DFG S
Sbjct: 112 LAARNILLCDEHFAKISDFGMS 47
>19761
Length = 473
Score = 62.4 bits (150), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 31/110 (28%), Positives = 61/110 (55%), Gaps = 4/110 (3%)
Frame = -3
Query: 127 ELYKELQKSEKLDEQRTATIIEELADALTYCHDKK--VIHRDIKPENLLLGFRGEVKIAD 184
++ L + L E+ + + A AL Y H ++HRD+KP+N+ + +G+V++ D
Sbjct: 465 KIVGHLGFTAGLPERLIVCWLMQTASALNYMHTHTPVILHRDLKPQNIYVTEKGDVRLGD 286
Query: 185 FGWS--VHTPSLRRKTMCGTLDYLPPEMIEGRTYDEKVDLWCIGVLCYEL 232
G + + P+ + GT+ YL PE++ + Y+ K D+W +G + Y++
Sbjct: 285 LGLARKLTGPADFATSQVGTIMYLSPEILSQQPYNSKSDIWSLGCVFYDI 136
>14116
Length = 1017
Score = 62.4 bits (150), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 58/215 (26%), Positives = 93/215 (43%), Gaps = 25/215 (11%)
Frame = -1
Query: 45 IGRPLGKGKFGNVYLARL----KESHFIVALKVLFKSQIEKEGLEHQLRREIEIQAHLQ- 99
+G +GKG FG V L ++ +VA+K L + REIE+Q+ LQ
Sbjct: 624 MGEEIGKGNFGCVKRGFLTLPEQKGDILVAVKTLHNNN----------PREIELQSFLQE 475
Query: 100 --------HPNILRLYNYFHDARRV-YLILEYAPRGELYKELQKSEKLDEQRTATIIE-- 148
H N+L L + + ++L + G+L ++ D+Q TI +
Sbjct: 474 ALIMKDFHHSNVLTLIGICLNLDDMPLVVLPFMKHGDLLTYIR-----DDQHQPTIKDLI 310
Query: 149 ----ELADALTYCHDKKVIHRDIKPENLLLGFRGEVKIADFG-----WSVHTPSLRRKTM 199
++A + Y K +HRD+ N +L VK+ADFG + S K
Sbjct: 309 MYGVDIARGMDYLAGLKFVHRDLAARNCMLDEDFHVKVADFGLARDIYEKEYYSSENKKA 130
Query: 200 CGTLDYLPPEMIEGRTYDEKVDLWCIGVLCYELLV 234
+ ++ E +E YD K D+W GV+ +ELL
Sbjct: 129 KLPVKWMALESLEKGNYDSKTDVWSYGVVLWELLT 25
>21808
Length = 1011
Score = 62.4 bits (150), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 43/166 (25%), Positives = 73/166 (43%), Gaps = 5/166 (3%)
Frame = +1
Query: 91 EIEIQAHLQHPNILRLYNYFHDARRVYLILEYAPRGELYKELQ-KSEKLDEQRTATIIEE 149
E +I L+HP +++LY +++I E G L + LQ K L I +
Sbjct: 82 EAQIMKKLRHPKLIQLYAVCTQDDPIFIITELMKNGSLLEFLQGKGRVLKLPALIDIGAQ 261
Query: 150 LADALTYCHDKKVIHRDIKPENLLLGFRGEVKIADFGWSVHTPSLRRKTMCGT---LDYL 206
+A + Y + IHRD+ N+L+ VKIADFG + + G + +
Sbjct: 262 IACGMAYLESQNYIHRDLAARNILVSDNNTVKIADFGLARVIKEDEYEARVGARFPIKWT 441
Query: 207 PPEMIEGRTYDEKVDLWCIGVLCYELLV-GYPPFESASHSETYRRI 251
PE + K D+W G+L E + G P+ +++E ++
Sbjct: 442 APEAANYNRFTIKSDVWSFGILLTETVTYGRVPYPGMTNAEVLHQV 579
>04852
Length = 1462
Score = 62.0 bits (149), Expect = 3e-10, Method: Compositional matrix adjust.
Identities = 59/256 (23%), Positives = 108/256 (42%), Gaps = 34/256 (13%)
Frame = +1
Query: 69 VALKVL--FKSQIEKEGLEHQLRREIEIQAHLQHPNILRLYNYFHDARRVYLILEYAPRG 126
VA+K+L + +E++ +L+ ++ H NI+ +++I+E+A G
Sbjct: 28 VAVKMLRDIVTAVEEQDFVQELQVMKAVKKMGSHINIVNFLGCCTQGGPLWVIVEFAKNG 207
Query: 127 EL-------------------------YKELQKSEKLDEQRTATIIEELADALTYCHDKK 161
L Y + + + + ++A + + +K
Sbjct: 208 NLRDFLESCRDGINGYGKFVSPQDPGWYTKTPGGHVIRRKNLLSYAFQIARGMEFLASRK 387
Query: 162 VIHRDIKPENLLLGFRGEVKIADFGWSVHTPSLRRKTMCGTL--DYLPPEMIEGRTYDEK 219
IHRD+ N+L+ +KIADFG S T +K G L ++ PE + Y K
Sbjct: 388 CIHRDLAARNVLVTEEHVLKIADFGLS-RTGDYYKKRSGGRLPVKWMAPEALFDMRYTTK 564
Query: 220 VDLWCIGVLCYELL-VGYPPFESASHSETYRRILKVDVRFP----LSMPLGARDLISRLL 274
D+W GV+ +E+ +G P+ S + E Y ++L R P S L A ++ R
Sbjct: 565 SDVWSFGVVLWEIFSLGGMPYASIPNEELYSKLLDDAYRMPRPELASGNLYA--IMERCW 738
Query: 275 RYQPLERLPLAQILKH 290
+P +R +Q++ H
Sbjct: 739 LNRPSDRPEFSQLVGH 786
>37602
Length = 804
Score = 50.8 bits (120), Expect(2) = 2e-09, Method: Compositional matrix adjust.
Identities = 33/104 (31%), Positives = 51/104 (49%), Gaps = 6/104 (5%)
Frame = -1
Query: 102 NILRLYNYFHDARR---VYLILEYAPRGELYKELQKSEKLDEQRTATIIEELADALTYCH 158
NI YF R +++ +EY G + + L E + A + E L Y H
Sbjct: 345 NIQTFVGYFDSYLRREKLWIAMEYCGGGSMQDIYHVTGPLTEPQIAFVCRETLKGLHYLH 166
Query: 159 DKKVIHRDIKPENLLLGFRGEVKIADFGWSV---HTPSLRRKTM 199
+ +HRDIK N+LL G+VK+ADF W V H+ ++++K
Sbjct: 165 RRGKMHRDIKGANILLTEEGDVKLADF-WRVSSNHSHNVQKKVF 37
Score = 28.1 bits (61), Expect(2) = 2e-09, Method: Compositional matrix adjust.
Identities = 12/26 (46%), Positives = 19/26 (73%)
Frame = -2
Query: 36 RRLTVDDFEIGRPLGKGKFGNVYLAR 61
RR +DDFE+ + +G G +G+VY A+
Sbjct: 524 RRNPLDDFELIQRVGSGTYGDVYKAK 447
>04138
Length = 800
Score = 57.0 bits (136), Expect = 8e-09, Method: Compositional matrix adjust.
Identities = 34/96 (35%), Positives = 51/96 (53%), Gaps = 6/96 (6%)
Frame = +1
Query: 154 LTYCHDKKVIHRDIKPENLLLGFRGEVKIADFG----WSVHTPSLRRKTM-CGTLDYLPP 208
L Y H K++HRD+K N+L+ +G +K+ADFG +SV+ R T TL Y PP
Sbjct: 52 LYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRPP 231
Query: 209 EMIEG-RTYDEKVDLWCIGVLCYELLVGYPPFESAS 243
E++ G R Y +D W G + E+ P + +
Sbjct: 232 ELLLGDRNYSTAIDQWGAGCIMAEMWTRNPIMQGTT 339
>28157
Length = 400
Score = 57.0 bits (136), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 44/123 (35%), Positives = 64/123 (52%), Gaps = 9/123 (7%)
Frame = +3
Query: 78 QIEKEGLEHQLRREIEIQAHLQHPNILRLYNYFHDARRVYLILEYAPRGELYKELQKSEK 137
+IE E + +E++ + + HPNI+ LY D V L++EYA G LY L S
Sbjct: 21 RIESEQEKKSFMQELKQLSRVSHPNIVCLYGACRD-HPVCLVMEYAEGGSLYNVLHGSGP 197
Query: 138 LDEQRTATIIE---ELADALTYCHD---KKVIHRDIKPENLLLGFRG-EVKIADFGWS-- 188
+ A + + A + Y H K +IHRD+KP NLLL G ++KI DFG +
Sbjct: 198 QPQYTAAHAMNWLLQCALGVEYLHGMKPKALIHRDLKPPNLLLIQCGTKLKICDFGTACD 377
Query: 189 VHT 191
+HT
Sbjct: 378 IHT 386
>38560
Length = 479
Score = 56.2 bits (134), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 31/98 (31%), Positives = 48/98 (48%), Gaps = 1/98 (1%)
Frame = -3
Query: 198 TMCGTLDYLPPEMIEGRTY-DEKVDLWCIGVLCYELLVGYPPFESASHSETYRRILKVDV 256
T CG+ Y PE+I G Y + D+W +GVL Y LL GY PF+ S ++ K
Sbjct: 408 TCCGSPAYAAPELISGLEYLGSEADIWSMGVLLYALLCGYLPFDDEKXSHL*QKNQKRKD 229
Query: 257 RFPLSMPLGARDLISRLLRYQPLERLPLAQILKHPWVQ 294
P + L+ +L+ P R+ + ++L H W+
Sbjct: 228 EVPEWLSEDTTKLLEGMLQTDPSHRITIRRLLDHHWLN 115
>00715
Length = 1788
Score = 55.8 bits (133), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 48/220 (21%), Positives = 90/220 (40%), Gaps = 31/220 (14%)
Frame = +1
Query: 69 VALKVLFKSQIEKEGLEHQLRREI-EIQAHLQHPNILRLYNY-----FHDARRVYLILEY 122
VA+K+ K L E+ + L+H N++ + F D +L +EY
Sbjct: 7 VAVKIYHKRSSNPRALRQSYSNELLAFRCGLRHVNVVSILGATSLHRFEDG--AWLAMEY 180
Query: 123 APRGELYKELQKSEK-LDEQRTATIIEELADALTYCHDKKVIHRDIKPENLLLGFRGEVK 181
L L ++ +D ++ ++A L Y H ++H D+KP N LL +++
Sbjct: 181 VGPLNLQTILNDHQQDIDSSMRLSLALQMARGLHYLHSINIVHLDLKPANCLLTRDLKLR 360
Query: 182 IADFGWSVH-TPS-----------------------LRRKTMCGTLDYLPPEMIEGRTYD 217
IADFG TP+ + + GTL Y PE+++G
Sbjct: 361 IADFGCCHQLTPTGLDMGEREGGMAGNELELTPVQGAWKNELAGTLAYRAPELLKGLQPS 540
Query: 218 EKVDLWCIGVLCYELLVGYPPFESASHSETYRRILKVDVR 257
+ D++ +G+ +++ P+E +++ D+R
Sbjct: 541 VRSDVYSLGITLWQMCTRQGPYEGVPAHAVVYQVVSKDLR 660
>07940
Length = 1336
Score = 55.5 bits (132), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 34/99 (34%), Positives = 52/99 (52%), Gaps = 5/99 (5%)
Frame = -3
Query: 149 ELADALTYCHDKKVIHRDIKPENLLLGFRGEVKIADFGWSVHTPSLR--RKTMCGTL--D 204
++A + Y K+ IHRD+ N+L+ +KIADFG + + RKT G L
Sbjct: 323 QVARGMEYLASKQCIHRDLAARNVLVAEEYVLKIADFGLTRNLQQFDYYRKTTDGRLPVK 144
Query: 205 YLPPEMIEGRTYDEKVDLWCIGVLCYELL-VGYPPFESA 242
++ PE + R Y K D+W GVL +E+ +G P+ S
Sbjct: 143 WMAPEALFDRKYTSKSDVWSYGVLLWEIFTLGGNPYPSV 27
Score = 38.5 bits (88), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 30/99 (30%), Positives = 56/99 (56%), Gaps = 6/99 (6%)
Frame = -3
Query: 45 IGRPLGKGKFGNVY----LARLKESHFI-VALKVLFKSQIEKEGLEHQLRREIEIQAHL- 98
+G LG+G FG V + K+++ + VA+K+L + ++E ++ L RE+E+ +
Sbjct: 830 LGDRLGEGAFGLVMKGEAMGIFKDNNSVTVAVKMLKEDATDREMMD--LIREMEMMKVIG 657
Query: 99 QHPNILRLYNYFHDARRVYLILEYAPRGELYKELQKSEK 137
+H NI+ L +Y+I+E+AP G L ++ KS +
Sbjct: 656 KHKNIINLLGCCTQRGALYVIVEFAPHGNL-RDFLKSHR 543
>12672
Length = 773
Score = 55.1 bits (131), Expect = 4e-08, Method: Compositional matrix adjust.
Identities = 33/96 (34%), Positives = 46/96 (47%), Gaps = 6/96 (6%)
Frame = +3
Query: 146 IIEELADALTYCHDKKVIHRDIKPENLLLGFRGEVKIADFGWSVHTPSLRRKT------M 199
I++ A + Y +D +HRDIK N+LL K+ DF V PS KT +
Sbjct: 6 IVKGTASGIQYLNDNGHVHRDIKTANILLDSEYTAKVGDFATVVSAPSGEGKTVQNASVV 185
Query: 200 CGTLDYLPPEMIEGRTYDEKVDLWCIGVLCYELLVG 235
GT YL PE I K+D + GV+ E++ G
Sbjct: 186 IGTAAYLAPEAIH-FDVSTKLDSYSFGVVLLEVITG 290
>27274
Length = 396
Score = 53.5 bits (127), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 29/96 (30%), Positives = 49/96 (51%), Gaps = 11/96 (11%)
Frame = -1
Query: 209 EMIEGRTYDEKVDLWCIGVLCYELLVGYPPFESASHS-ETYRRILKV----------DVR 257
E++ G+ + VD+W +G+L +ELL G+ PFE S + R ++ V DV
Sbjct: 375 ELLRGQQHGPTVDMWSLGILLHELLSGHVPFEPERGSRQMARNMMAVYAQIIRGSSRDVC 196
Query: 258 FPLSMPLGARDLISRLLRYQPLERLPLAQILKHPWV 293
L++ D + RL++ + +RL Q HPW+
Sbjct: 195 DGLALSTHGADFLRRLVQLEDTKRLTSQQAFSHPWI 88
>28638
Length = 1458
Score = 53.1 bits (126), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 36/111 (32%), Positives = 53/111 (47%), Gaps = 4/111 (3%)
Frame = -1
Query: 133 QKSEKLDEQRTATIIEELADALTYCH--DKKVIHRDIKPENLLLGF--RGEVKIADFGWS 188
Q E + T ++L AL + + +IH D+KPEN+LL R +KI DFG S
Sbjct: 861 QTLEGVSLNLTRKFAQQLCTALLFLATPEMNIIHCDLKPENILLCNPKRSAIKIVDFGSS 682
Query: 189 VHTPSLRRKTMCGTLDYLPPEMIEGRTYDEKVDLWCIGVLCYELLVGYPPF 239
R + Y PE++ G YD +D+W +G + E+ G PP
Sbjct: 681 CQLGQ-RIYQYIQSRFYRSPEVLLGVPYDLAIDMWSLGCILVEMHTGEPPL 532
>07291
Length = 833
Score = 52.0 bits (123), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 30/107 (28%), Positives = 55/107 (51%), Gaps = 12/107 (11%)
Frame = +1
Query: 149 ELADALTYCHDKKVIHRDIKPENLLLGFRGEVKIADFGWSVHTPSLRRKTMCGTLD---- 204
++AD + Y + KV+HR++ N ++ G ++++D+G T SL ++ D
Sbjct: 73 QIADGMAYLQEVKVVHRNLAARNCIVTEDGRLQLSDYG---VTGSLFPQSYYTADDSPAR 243
Query: 205 ----YLPPEMIEGRTYDEKVDLWCIGVLCYELL----VGYPPFESAS 243
++ PE I+ + K D+W GV+ +ELL YP E++S
Sbjct: 244 DLVKWMAPETIDNFHFSSKSDVWAFGVVLWELLTRGITPYPDVENSS 384
>20559
Length = 430
Score = 49.3 bits (116), Expect(2) = 5e-07, Method: Compositional matrix adjust.
Identities = 27/78 (34%), Positives = 47/78 (60%)
Frame = -2
Query: 43 FEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLRREIEIQAHLQHPN 102
+E +G+G +G V+ A+ +E+H IVALK + + + EG+ REI + L+H N
Sbjct: 369 YEKLEKIGEGTYGTVFKAKNRETHEIVALKRV-RLDDDDEGVPSSALREICLLKELKHRN 193
Query: 103 ILRLYNYFHDARRVYLIL 120
I+RL++ H R++ L+
Sbjct: 192 IVRLHDVLHSERKLTLVF 139
Score = 21.6 bits (44), Expect(2) = 5e-07, Method: Compositional matrix adjust.
Identities = 9/30 (30%), Positives = 15/30 (50%)
Frame = -1
Query: 136 EKLDEQRTATIIEELADALTYCHDKKVIHR 165
EKL + ++ + L +CH V+HR
Sbjct: 91 EKLIQTLSSHFSTSY*EDLVFCHSNNVLHR 2
>12786
Length = 460
Score = 50.4 bits (119), Expect = 9e-07, Method: Compositional matrix adjust.
Identities = 33/132 (25%), Positives = 56/132 (42%), Gaps = 24/132 (18%)
Frame = -3
Query: 133 QKSEKLDEQRTATIIEELADALTYCHDKKVIHRDIKPENLLLGFRGEVKIADFGWSV--- 189
++ + LD E+ A+ H++ VIH D+KP N +L G +K+ DFG +
Sbjct: 434 KQEQGLDRMMIKFYWREMLRAVKALHNEGVIHSDLKPANFML-VAGNLKLIDFGIANTLQ 258
Query: 190 -HTPSLRRKTMCGTLDYLPPEMIEGRTYDE--------------------KVDLWCIGVL 228
S+ + + GT Y+ PE I D + D+W +G +
Sbjct: 257 QDKTSVLKDSRVGTPSYMSPEAIMAACDDSADDSMEEDGHRTKPKYKVGVRSDVWSLGCI 78
Query: 229 CYELLVGYPPFE 240
Y ++ G PF+
Sbjct: 77 LYNMVYGRTPFQ 42
>17722
Length = 680
Score = 50.4 bits (119), Expect = 9e-07, Method: Compositional matrix adjust.
Identities = 30/95 (31%), Positives = 47/95 (49%), Gaps = 11/95 (11%)
Frame = -3
Query: 220 VDLWCIGVLCYELLVGYPPFESASHSETYRRILKVDVRFPLSMPLGARDLISRLLRYQPL 279
VD W GV+ YE++ G PF + H + IL +V+FP ++ A+ L+S LL P
Sbjct: 678 VDWWGTGVVMYEMMCGRLPFYNRDHDVLFELILLQNVKFPRNLSEEAKTLLSGLLAKNPK 499
Query: 280 ERL-----PLAQILKHP------WVQAHSRRVLPP 303
RL + +I HP W ++++ PP
Sbjct: 498 RRLGGSEADVTEIKTHPFFQCINWDDLAAKKITPP 394
>03508
Length = 1463
Score = 49.7 bits (117), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 42/193 (21%), Positives = 91/193 (47%), Gaps = 5/193 (2%)
Frame = +1
Query: 41 DDFEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLRREIEIQAHLQH 100
DD++I R LG+GK+ V+ E+ + + ++ + R ++
Sbjct: 589 DDYQIVRKLGRGKYSEVF-----EAINVTNNEKCVIKILKPVKKKKIKREIKILENLRGG 753
Query: 101 PNILRLYNYFHD--ARRVYLILEYAPRGELYKELQKSEKLDEQRTATIIEELADALTYCH 158
N++ L D +R LI E+ + +K+L ++ + + EL AL +CH
Sbjct: 754 TNVITLLAIVKDPVSRTPALIFEHVNNTD-FKQLYQT--FTDYDIRFYLYELMKALDFCH 924
Query: 159 DKKVIHRDIKPENLLLGFRG-EVKIADFGWS-VHTPSLRRKTMCGTLDYLPPE-MIEGRT 215
++HRD+KP N+++ ++++ D+G + + P + + + PE +++ +
Sbjct: 925 SMGIMHRDVKPHNVMIDHENKKLRLIDWGLAEFYHPGMEYNVRVASRYFKGPELLLDYQM 1104
Query: 216 YDEKVDLWCIGVL 228
YD +D+W +G +
Sbjct: 1105YDYSLDMWSLGCM 1143
>11185
Length = 473
Score = 48.5 bits (114), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 27/110 (24%), Positives = 46/110 (41%), Gaps = 24/110 (21%)
Frame = +1
Query: 150 LADALTYCHDKKVIHRDIKPENLLLGFRGEVKIADFG----------------------W 187
L L Y H ++ D++P +LL G +K ADFG W
Sbjct: 28 LVTGLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQW 207
Query: 188 SVHTPS--LRRKTMCGTLDYLPPEMIEGRTYDEKVDLWCIGVLCYELLVG 235
++ + +++ G+ Y+ PE+ +G DLW +G + YE+ G
Sbjct: 208 NIQSAEEMMKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSG 357
>16708
Length = 1397
Score = 46.6 bits (109), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 39/149 (26%), Positives = 60/149 (40%), Gaps = 11/149 (7%)
Frame = -1
Query: 49 LGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLRREIEIQAHLQHPNIL-RLY 107
LGKG FG VY ARL +H ALK L H E+E ++ L +++
Sbjct: 1379 LGKGVFGKVYEARLLSTHEKAALKTSI--------LCHHSLDEVEALGRIEGGFYLAQMF 1224
Query: 108 NY------FHDARRVYLILEYAPRGELYKELQKSEK----LDEQRTATIIEELADALTYC 157
F + E P +Y + E + I + AL +
Sbjct: 1223 GAWVTCLPFPKMNILLHFYEMGPLCNVYAHYKNKEMPIRWSNPAMVCCIAGQXVCALEHI 1044
Query: 158 HDKKVIHRDIKPENLLLGFRGEVKIADFG 186
H+ V+H D+K +N+L+ G K+ D+G
Sbjct: 1043 HELGVVHMDVKADNVLVDAHGNCKLTDYG 957
>26009
Length = 886
Score = 46.6 bits (109), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 31/102 (30%), Positives = 53/102 (51%), Gaps = 2/102 (1%)
Frame = +2
Query: 43 FEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLRREIEIQAHLQ-HP 101
+++ + LG+G +G V LAR + + VALK+L KS + + +RE ++ L H
Sbjct: 422 YDVCKELGRGTYGKVVLARCRHTGTQVALKLLPKSCTKL----REFQREFQLSYFLSPHA 589
Query: 102 NILRLYNYFHDARRVYLIL-EYAPRGELYKELQKSEKLDEQR 142
NI+ YN R Y+ E+A G+L+ + + + E R
Sbjct: 590 NIIDTYNVAFQTRSSYVFAQEHAVLGDLFDAIPPQQGMRESR 715
Score = 41.6 bits (96), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 15/49 (30%), Positives = 31/49 (63%)
Frame = +3
Query: 126 GELYKELQKSEKLDEQRTATIIEELADALTYCHDKKVIHRDIKPENLLL 174
G ++++ + +++++L AL + H K+++HRDIKPEN+L+
Sbjct: 666 GTCLTPSRRNKACGSREAKSVMKQLVSALDFMHSKQLVHRDIKPENVLI 812
>02638
Length = 1490
Score = 46.2 bits (108), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 28/103 (27%), Positives = 45/103 (43%), Gaps = 5/103 (4%)
Frame = +1
Query: 201 GTLDYLPPEMIEGRTYDEKVDLWCIGVLCYELLVGYPPFESASHSETYRRILKVDVR--- 257
GT+ ++ PE++ G +Y D+W +G + E+ PP+ S S I K+
Sbjct: 22 GTIAFMAPEVLRGESYGRACDVWSVGCVMIEMCTCRPPWNSHDISNHLALIFKIASSVDP 201
Query: 258 --FPLSMPLGARDLISRLLRYQPLERLPLAQILKHPWVQAHSR 298
P +M RDL+ R L R +L HP +S+
Sbjct: 202 PPIPENMSPPVRDLMLRCLEQDSDFRPSAKDLLMHPLFTKYSQ 330
>07833
Length = 1504
Score = 45.4 bits (106), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 39/187 (20%), Positives = 82/187 (43%), Gaps = 9/187 (4%)
Frame = -3
Query: 98 LQHPNILRLYNYFHDARRVYLILEYAPRGELYKELQKSEKL--DEQRTATIIEELADALT 155
HPN+L + + + LI ++ P G LY L + D+ ++ ++A +
Sbjct: 1448 FNHPNVLPVLACCNQPPNLVLISQFMPFGSLYNTLHGESGIVVDQNQSLRFAMDIARGME 1269
Query: 156 YCH--DKKVIHRDIKPENLLL--GFRGEVKIADFGWSVHTPSLRRKTMCGTLDYLPPEMI 211
+ H + + + + +++++ + +AD+ +S H K + ++ PE +
Sbjct: 1268 FLHSMEPTIPNFLLTSKHVMIDEDLTARINMADYCFSFH-----EKGKVYSPAWMAPEAL 1104
Query: 212 EGRTYD---EKVDLWCIGVLCYELLVGYPPFESASHSETYRRILKVDVRFPLSMPLGARD 268
+ R D D+W +L +EL PF S E ++ +R +S+P G
Sbjct: 1103 QRRPDDINTRAADMWSFAILMWELETREVPFAELSSMEVGMKVALEGLR--ISIPPGISL 930
Query: 269 LISRLLR 275
+SRL++
Sbjct: 929 HMSRLIK 909
>20640
Length = 1492
Score = 45.1 bits (105), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 28/94 (29%), Positives = 46/94 (48%), Gaps = 5/94 (5%)
Frame = +1
Query: 163 IHRDIKPENLLLGFRGEVKIADFGW--SVHTPSLRRKTMCGT--LDYLPPEMIEGRTYDE 218
+HRD+ N L+G VKI+DFG SVH+ R + + ++P E I +
Sbjct: 10 VHRDLATRNCLVGHDLVVKISDFGLARSVHSVDYYRGSEHDAIPIRWMPLEAILYNKFST 189
Query: 219 KVDLWCIGVLCYELLV-GYPPFESASHSETYRRI 251
+ D+W GV+ +E+ P+ +H E R +
Sbjct: 190 QSDVWSFGVVLWEIFAFALQPYYGLTHEEVVRFV 291
>32957
Length = 645
Score = 45.1 bits (105), Expect = 4e-05, Method: Compositional matrix adjust.
Identities = 20/50 (40%), Positives = 30/50 (60%)
Frame = +3
Query: 185 FGWSVHTPSLRRKTMCGTLDYLPPEMIEGRTYDEKVDLWCIGVLCYELLV 234
F V R +T CGT +Y+ PE+ E + Y ++VD W +G+L +ELL
Sbjct: 3 FALCVEKSGGRTRTFCGTREYMAPEVHERKEYGKEVDWWGLGILLHELLA 152
>17253
Length = 483
Score = 44.3 bits (103), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 30/133 (22%), Positives = 61/133 (45%), Gaps = 13/133 (9%)
Frame = -1
Query: 69 VALKVLFKSQIEKEGLEHQLRREIEIQAHL-QHPNILRLYNYFHDARRVYLILEYAPRGE 127
VA+K ++ + E + + RE+ I L +HPN++ + +++E+ G+
Sbjct: 459 VAVKTHNEAATDAE--KSEFLRELSIMRKLPRHPNVVSFMGCCTMSDPALILMEFCCHGD 286
Query: 128 LYKELQK------------SEKLDEQRTATIIEELADALTYCHDKKVIHRDIKPENLLLG 175
L L+K + L + + +A + + + K++HRD+ N+L+
Sbjct: 285 LLSFLRKRRPDRTVFLTSTANDLTARDFFSFALHVARGMAHVANNKIVHRDVAARNVLIS 106
Query: 176 FRGEVKIADFGWS 188
R K++DFG S
Sbjct: 105 ERNVCKVSDFGLS 67
>07836
Length = 1478
Score = 43.9 bits (102), Expect = 9e-05, Method: Compositional matrix adjust.
Identities = 48/190 (25%), Positives = 81/190 (42%), Gaps = 26/190 (13%)
Frame = -1
Query: 69 VALKVLFKSQIEKEGLEHQLRREIEI--QAHLQHPNILRLY----NYFHDARRVYLILEY 122
VA+K+ F ++ E RE E+ L+H NIL +++LI +Y
Sbjct: 1469 VAVKIFFTTE------EASWFRETELYQTVLLRHENILGFIAADIKGTGSWTQLFLITDY 1308
Query: 123 APRGELYKELQKSEKLDEQRTATIIEELADALTYCHDK--------KVIHRDIKPENLLL 174
G L+ L S LD + L + H + + HRDIK +N+L+
Sbjct: 1307 HENGSLHDYLL-SRVLDSSEMLALAHSAICGLAHLHIEIFGTRGKPAIAHRDIKSKNILV 1131
Query: 175 GFRGEVKIADFGWSVHTPSLRRKTMC------GTLDYLPPEMIEG----RTYD--EKVDL 222
G IAD G +V S + GT Y+ PE++E + +D ++ D+
Sbjct: 1130 KKNGTCCIADLGLAVRYISESNEVDVAPNPRQGTKRYMAPEVLEMLLNVKNFDAFKQADM 951
Query: 223 WCIGVLCYEL 232
+ G++ +E+
Sbjct: 950 YAFGLVMWEI 921
>31489
Length = 329
Score = 43.1 bits (100), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 23/88 (26%), Positives = 46/88 (52%), Gaps = 6/88 (6%)
Frame = +3
Query: 92 IEIQAHLQHPNILRL------YNYFHDARRVYLILEYAPRGELYKELQKSEKLDEQRTAT 145
I+I H +H NI+ + + +HD + ++++ + +L++ + + L E+
Sbjct: 3 IKILKHFKHDNIISIREILKPKDSYHDFKDIHVVFDLM-ESDLHRIIYSDQPLTEEHIRY 179
Query: 146 IIEELADALTYCHDKKVIHRDIKPENLL 173
+ ++ L Y H V+HRD+KP NLL
Sbjct: 180 FLYQILRGLKYIHSANVVHRDLKPSNLL 263
>17300
Length = 480
Score = 42.0 bits (97), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 30/118 (25%), Positives = 53/118 (44%), Gaps = 7/118 (5%)
Frame = +1
Query: 150 LADALTYCHDKKVIHRDIKPENLLLGFRGEVKIADFGWSVHTPSLRRKTMCGT------L 203
++ + D +HRD+ N+L+ K+ADFG S S + T +
Sbjct: 1 ISSGMGXLADMGYVHRDLAARNILVNEILVCKVADFGLSREIESDTTEGAYTTKGGKIPV 180
Query: 204 DYLPPEMIEGRTYDEKVDLWCIGVLCYELL-VGYPPFESASHSETYRRILKVDVRFPL 260
+ PE I R + D+W GV+ +E++ G P+ + S+ + + + K R PL
Sbjct: 181 RWTAPEAIAYRKFTSASDVWSFGVVMWEVMSYGERPYWNWSNQDVIKAVEK-GYRLPL 351
>31789
Length = 676
Score = 40.8 bits (94), Expect = 7e-04, Method: Compositional matrix adjust.
Identities = 40/116 (34%), Positives = 54/116 (46%), Gaps = 6/116 (5%)
Frame = +2
Query: 30 PSSPAMRRLTVDDFEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQ-L 88
SSP R L D EIGR G F VY E VA L + K E Q
Sbjct: 302 ASSPDNRFLKFD-VEIGR----GSFKTVYKGLDTELGVAVAWCELQDKKWNK--TERQRF 460
Query: 89 RREIEIQAHLQHPNILRLYNYF----HDARRV-YLILEYAPRGELYKELQKSEKLD 139
+ E E+ LQHPNI+R ++Y+ H R+V L+ E G L L++ +K++
Sbjct: 461 KEEAEMLKELQHPNIVRFFDYWEEHNHRNRKVIILVTELMTSGTLKTYLKRFKKIN 628
>11404
Length = 563
Score = 38.9 bits (89), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 42/145 (28%), Positives = 68/145 (46%), Gaps = 11/145 (7%)
Frame = +1
Query: 41 DDFEIGRPLGKGKFGNVYLARLKESHFIVALKV-------LFKSQIEKEGLEHQLRREIE 93
D +EI +GKG FG V A + VA+K+ L ++QIE + LE R + +
Sbjct: 139 DRYEIDSLIGKGSFGQVVKAYDHTDNEQVAIKIIKNKKPFLNQAQIEVKLLEMMNRHDTD 318
Query: 94 IQAHLQHPNILRLYNYFHDARRVYLILEYAPRGELYKELQKSE--KLDEQRTATIIEELA 151
+ + I+RL +F + L+ E LY L+ + + T ++L
Sbjct: 319 NKYY-----IVRLKRHFMFRSHLCLVFELLSYN-LYDLLRNTNFRGVSLNLTRKFAQQLC 480
Query: 152 DALTYCH--DKKVIHRDIKPENLLL 174
AL + + +IH D+KPEN+LL
Sbjct: 481 TALLFLATPEMSIIHCDLKPENILL 555
>29590
Length = 320
Score = 38.1 bits (87), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 20/53 (37%), Positives = 28/53 (52%), Gaps = 3/53 (5%)
Frame = +3
Query: 201 GTLDYLPPEMIEGRTYDEKVDLWCIGVLCYELLVGYPPF---ESASHSETYRR 250
GT DY+ PE+++ + D+W +GVL Y +L PF S HS T R
Sbjct: 60 GTPDYVAPEVLDYEPLSIQTDMWSLGVLSYVMLTACSPFVGITSKKHSATSLR 218
>00394
Length = 548
Score = 37.4 bits (85), Expect = 0.008, Method: Compositional matrix adjust.
Identities = 32/102 (31%), Positives = 45/102 (44%), Gaps = 5/102 (4%)
Frame = -2
Query: 32 SPAMRRLTVDDFEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLRRE 91
SP R L D + +G+G F VY E VA L + K + + E
Sbjct: 310 SPDNRFLKFD-----KEIGRGSFKTVYKGLDTELGVAVAWCELQDKKWNK-AERQRFKEE 149
Query: 92 IEIQAHLQHPNILRLYNYF----HDARRV-YLILEYAPRGEL 128
E+ LQHPNI+R ++Y+ H R+V L+ E G L
Sbjct: 148 AEMLKELQHPNIVRFFDYWEEHNHRNRKVIILVTELMTSGTL 23
>01106
Length = 878
Score = 37.0 bits (84), Expect = 0.009, Method: Compositional matrix adjust.
Identities = 37/143 (25%), Positives = 66/143 (46%), Gaps = 11/143 (7%)
Frame = +3
Query: 43 FEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLR-----REIEIQAH 97
+ + R LG G F V+L VALKV+ +Q E +++ RE ++ A
Sbjct: 324 YHVIRKLGWGHFSTVWLCWDLTCKRFVALKVVKSAQHYTETALDEVKLLKCVRESDV-AD 500
Query: 98 LQHPNILRLYNYFH----DARRVYLILEYAPRGELYKELQKS-EKLDEQRTATIIEELAD 152
++L + F + V ++ E L ++ + + + II ++ +
Sbjct: 501 PARAKCVQLLDDFKISGVNGTHVAMVFEVLGYNLLKLIIRSNYQGIPIHNVKLIIRQVLE 680
Query: 153 ALTYCHDK-KVIHRDIKPENLLL 174
L+Y H K ++IH DIKPEN+L+
Sbjct: 681 GLSYMHAKCRIIHTDIKPENILI 749
>31120
Length = 439
Score = 36.6 bits (83), Expect = 0.012, Method: Compositional matrix adjust.
Identities = 29/98 (29%), Positives = 46/98 (46%), Gaps = 11/98 (11%)
Frame = +1
Query: 209 EMIEGRTYDEKV-DLWCIGVLCYELLVGYPPFESA----------SHSETYRRILKVDVR 257
E++ G YD K+ D W +GV+ + +L G PF+ + S ++RR L+ D+
Sbjct: 1 EVVCGVPYDPKMADAWSLGVILFIMLNGKMPFDDSNLNKLLEDQRSKKYSFRRKLQ-DLV 177
Query: 258 FPLSMPLGARDLISRLLRYQPLERLPLAQILKHPWVQA 295
P AR +S LL R L ++L W+Q
Sbjct: 178 SP-----NARSTVSVLLEPNSAMRWDLNEVLNCQWLQT 276
>18481
Length = 437
Score = 36.6 bits (83), Expect = 0.013, Method: Compositional matrix adjust.
Identities = 33/118 (27%), Positives = 58/118 (49%), Gaps = 7/118 (5%)
Frame = -1
Query: 78 QIEKEGLEHQL-RREIEIQAHL-QHPNILRLYNYFHDARRVYLILEYAPRG--ELYKELQ 133
+IE ++HQL E ++ + +HP + +Y+Y + L++E EL+ +
Sbjct: 392 KIEAIDVKHQLLHYEAKVYEQIGRHPGLPTMYHYGTEKHFNALVMELLGPSLEELFVICK 213
Query: 134 KSEKLDEQRTATIIEELADALTYCHDKKVIHRDIKPENLLLGFR---GEVKIADFGWS 188
+ L + + ++L L + H K IHRD+KP+N L+G + I DFG S
Sbjct: 212 RRFTL--KTILMVSDQLLSRLEFIHQKCFIHRDLKPDNFLMGLGRHCHRLYIIDFGLS 45
>18401
Length = 463
Score = 36.6 bits (83), Expect = 0.014, Method: Compositional matrix adjust.
Identities = 15/49 (30%), Positives = 25/49 (51%)
Frame = -3
Query: 198 TMCGTLDYLPPEMIEGRTYDEKVDLWCIGVLCYELLVGYPPFESASHSE 246
T+ T Y PE+I + D+W +G + +EL GY F++ + E
Sbjct: 455 TIVSTRHYRAPEVILELGWSHPCDVWSVGCIMFELYTGYTLFQTHDNKE 309
>37063
Length = 455
Score = 35.8 bits (81), Expect = 0.021, Method: Compositional matrix adjust.
Identities = 26/79 (32%), Positives = 40/79 (50%), Gaps = 17/79 (21%)
Frame = -2
Query: 167 IKPENLLLGFRGEV---KIADF---------GWSVHTPSLRRKTMCGTLDYLPPEMI--- 211
+KPEN+L EV KI DF G TP L T G+ +Y+ PE++
Sbjct: 454 LKPENILCEHLDEVVPLKICDFDLASGINCDGDGTKTPELL--TPVGSAEYMAPEVVDAW 281
Query: 212 --EGRTYDEKVDLWCIGVL 228
E +YD++ D+W +G++
Sbjct: 280 VGESFSYDKRCDMWSLGII 224
>36002
Length = 253
Score = 35.0 bits (79), Expect = 0.034, Method: Compositional matrix adjust.
Identities = 19/50 (38%), Positives = 27/50 (54%), Gaps = 4/50 (8%)
Frame = +1
Query: 248 YRRILKVDVRFPL----SMPLGARDLISRLLRYQPLERLPLAQILKHPWV 293
+ RI + FP ++ A+DLI LL +P +R A +LKHPWV
Sbjct: 61 FNRIQDGNYFFPSMEWSAISSSAKDLIRHLLVREPRKRYSAADVLKHPWV 210
>21800
Length = 855
Score = 32.3 bits (72), Expect = 0.22, Method: Compositional matrix adjust.
Identities = 15/30 (50%), Positives = 21/30 (70%), Gaps = 1/30 (3%)
Frame = +2
Query: 146 IIEELADALTYCHDK-KVIHRDIKPENLLL 174
II ++ + L Y H K +IH DIKPEN+L+
Sbjct: 647 IIRQVLEGLNYLHAKCNIIHTDIKPENILI 736
>00638
Length = 1595
Score = 31.6 bits (70), Expect = 0.47, Method: Compositional matrix adjust.
Identities = 11/21 (52%), Positives = 15/21 (71%)
Frame = +2
Query: 149 ELADALTYCHDKKVIHRDIKP 169
EL AL +CH ++HRD+KP
Sbjct: 440 ELMKALDFCHSMGIMHRDVKP 502
Score = 28.1 bits (61), Expect = 4.3, Method: Compositional matrix adjust.
Identities = 11/26 (42%), Positives = 17/26 (65%)
Frame = +1
Query: 35 MRRLTVDDFEIGRPLGKGKFGNVYLA 60
+ R DD++I R LG+GK+ V+ A
Sbjct: 115 LSRRNQDDYQIVRKLGRGKYSEVFEA 192
>03106
Length = 2384
Score = 30.0 bits (66), Expect = 1.3, Method: Compositional matrix adjust.
Identities = 19/64 (29%), Positives = 28/64 (43%), Gaps = 1/64 (1%)
Frame = +2
Query: 219 KVDLWCIGVLCYELLVGYPPFESASHSETYRRILKVDV-RFPLSMPLGARDLISRLLRYQ 277
K D+W G + YE+ PF S S Y + D+ P P G L++ +L
Sbjct: 26 KADVWAAGAVAYEIFGASNPFYSRLDSACYS---QHDLPSLPGDTPEGVVRLVTSMLERD 196
Query: 278 PLER 281
P +R
Sbjct: 197 PAQR 208
>20160
Length = 1277
Score = 29.6 bits (65), Expect = 1.8, Method: Compositional matrix adjust.
Identities = 16/39 (41%), Positives = 19/39 (48%)
Frame = +2
Query: 266 ARDLISRLLRYQPLERLPLAQILKHPWVQAHSRRVLPPC 304
A DLI+R + P R LA ILKH W+ L C
Sbjct: 338 AADLINRCIALDPSTRPVLADILKHKWMTKDYEYHLTSC 454
>38046
Length = 446
Score = 29.3 bits (64), Expect = 1.9, Method: Compositional matrix adjust.
Identities = 12/32 (37%), Positives = 19/32 (59%)
Frame = -1
Query: 150 LADALTYCHDKKVIHRDIKPENLLLGFRGEVK 181
+ADA+ Y + IHR++ N+L+G VK
Sbjct: 98 IADAMAYMEKENFIHRNLGDRNILVGPNNRVK 3
>13078
Length = 773
Score = 28.9 bits (63), Expect = 2.7, Method: Compositional matrix adjust.
Identities = 12/40 (30%), Positives = 21/40 (52%)
Frame = -1
Query: 207 PPEMIEGRTYDEKVDLWCIGVLCYELLVGYPPFESASHSE 246
PP+ + + D+W IG + +EL GY F++ + E
Sbjct: 773 PPK*S*SWGWSQPCDVWSIGCIMFELYTGYTLFQTHDNKE 654
>36481
Length = 806
Score = 28.9 bits (63), Expect = 2.8, Method: Compositional matrix adjust.
Identities = 10/26 (38%), Positives = 18/26 (69%)
Frame = +2
Query: 149 ELADALTYCHDKKVIHRDIKPENLLL 174
+L A+ + H+ ++ H D+KPEN+L
Sbjct: 695 QLCYAVNFLHENQLTHTDLKPENILF 772
>03063
Length = 848
Score = 28.5 bits (62), Expect = 3.7, Method: Compositional matrix adjust.
Identities = 15/48 (31%), Positives = 22/48 (45%)
Frame = -3
Query: 163 IHRDIKPENLLLGFRGEVKIADFGWSVHTPSLRRKTMCGTLDYLPPEM 210
I + N LLG R V++ +F S T +R +T C L P+
Sbjct: 789 IRNGLMDHNXLLGERELVRLEEFAASQSTGEVRDRTRCDVLRVCTPDF 646
>20513
Length = 405
Score = 28.5 bits (62), Expect = 3.8, Method: Compositional matrix adjust.
Identities = 10/27 (37%), Positives = 18/27 (66%)
Frame = -1
Query: 268 DLISRLLRYQPLERLPLAQILKHPWVQ 294
D ++ +L + P +R AQ L+HPW++
Sbjct: 282 DFLAPMLEFDPEQRATAAQSLQHPWLK 202
>06342
Length = 2428
Score = 28.1 bits (61), Expect = 4.8, Method: Compositional matrix adjust.
Identities = 16/49 (32%), Positives = 24/49 (48%)
Frame = +2
Query: 122 YAPRGELYKELQKSEKLDEQRTATIIEELADALTYCHDKKVIHRDIKPE 170
YAP GELY+ +K + D +EEL C+D V + + K +
Sbjct: 737 YAPDGELYQNGKKVKASDYPG----LEELCTICGMCNDSSVDYNEAKTQ 871
>16350
Length = 1108
Score = 28.1 bits (61), Expect = 5.3, Method: Compositional matrix adjust.
Identities = 10/27 (37%), Positives = 18/27 (66%)
Frame = +3
Query: 268 DLISRLLRYQPLERLPLAQILKHPWVQ 294
D ++ +L + P +R AQ L+HPW++
Sbjct: 762 DFLAPMLEFDPEQRATAAQSLQHPWLK 842
>21418
Length = 831
Score = 27.7 bits (60), Expect = 6.1, Method: Compositional matrix adjust.
Identities = 10/33 (30%), Positives = 19/33 (57%)
Frame = +2
Query: 265 GARDLISRLLRYQPLERLPLAQILKHPWVQAHS 297
A+DLI +L P +RL + +L++ W+ +
Sbjct: 68 AAKDLIKGMLNVDPSKRLCIEDVLRNKWIAQYD 166
>17637
Length = 447
Score = 27.3 bits (59), Expect = 7.9, Method: Compositional matrix adjust.
Identities = 24/90 (26%), Positives = 40/90 (44%), Gaps = 5/90 (5%)
Frame = +1
Query: 203 LDYLPPEMIEGRTYDEKVDLWCIGVLCYELL-VGYPPFESASHSETYRRILKVDVRFPLS 261
+ +L E ++ Y+E D+W GVL +E+ +G P+ E LK R L+
Sbjct: 109 IKWLSLEALQKSHYNEGSDVWSFGVLMWEMCTLGKLPYAEIDPYEM-EHYLKDGYR--LA 279
Query: 262 MPLGARDLISRLLRY----QPLERLPLAQI 287
P D + ++ Y P ER +Q+
Sbjct: 280 QPFNCPDELFTIMAYCWASMPAERPSFSQL 369
>18874
Length = 1177
Score = 26.9 bits (58), Expect = 9.4, Method: Compositional matrix adjust.
Identities = 14/39 (35%), Positives = 23/39 (58%), Gaps = 3/39 (7%)
Frame = -2
Query: 268 DLISRLL---RYQPLERLPLAQILKHPWVQAHSRRVLPP 303
DL S L+ +PLE++ A + ++ W +A RR+ PP
Sbjct: 852 DLYSHLVPVYDVEPLEKITDAYLDQYLWYEADKRRLFPP 736
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000366262 | hsapiens_gene_ensembl |
6-phosphogluconate dehydrogenase, decarboxylating (EC 1.1.1.44).
[Source:Uniprot/SWISSPROT;Acc:P52209]
(483 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
02744 228 6e-60
00782 30 2.7
34301 30 3.1
>02744
Length = 3030
Score = 228 bits (580), Expect = 6e-60, Method: Compositional matrix adjust.
Identities = 101/146 (69%), Positives = 116/146 (79%)
Frame = -1
Query: 338 GFMLLRQAATEFGWTLNYGGIALMWRGGCIIRSVFLGKIKDAFDRNPELQNLLLDDFFKS 397
GFML+R+ A E GW LN G IALMWRGGCIIRSVFLG IK AFD NP+L NLLLD FFK
Sbjct: 3030 GFMLMRETAKELGWKLNMGAIALMWRGGCIIRSVFLGNIKQAFDNNPDLSNLLLDKFFKE 2851
Query: 398 AVENCQDSWRRAVSTGVQAGIPMPCFTTALSFYDGYRHEMLPASLIQAQRDYFGAHTYEL 457
+ CQ+SWRR ++ V GIP P F+TAL+F+DGYR LPA+LIQAQRDYFGAHTYE
Sbjct: 2850 EIIKCQESWRRVMAQAVTLGIPTPAFSTALAFFDGYRSASLPANLIQAQRDYFGAHTYER 2671
Query: 458 LAKPGQFIHTNWTGHGGTVSSSSYNA 483
L PG+F+HTNWTGHGG VSS++Y A
Sbjct: 2670 LDNPGKFVHTNWTGHGGNVSSTTYQA 2593
>00782
Length = 1035
Score = 29.6 bits (65), Expect = 2.7, Method: Compositional matrix adjust.
Identities = 11/33 (33%), Positives = 21/33 (63%)
Frame = +3
Query: 209 LGMAQDEMAQAFEDWNKTELDSFLIEITANILK 241
+GM ++++ Q +ED ++E+ F EI + I K
Sbjct: 279 MGMNEEDLKQKYEDQLQSEMSGFEYEIVSRIFK 377
>34301
Length = 429
Score = 29.6 bits (65), Expect = 3.1, Method: Composition-based stats.
Identities = 26/113 (23%), Positives = 45/113 (39%), Gaps = 8/113 (7%)
Frame = -1
Query: 343 RQAATEFGWTLNYGGIALMWRGGCIIRSVFLGKIKDAFDRNPELQNLLLDDFFKSAVEN- 401
R + + + +N + L R G + FL I + F R E +++ + + N
Sbjct: 408 RLPSASYHYLVNAFPVILPPRWGTETSAAFLVNIDNQFVRPAEALQFMVERSERQILSNS 229
Query: 402 -------CQDSWRRAVSTGVQAGIPMPCFTTALSFYDGYRHEMLPASLIQAQR 447
C DS R +T V+A PC TT + + + P S+ +R
Sbjct: 228 STPSTPCCLDSSRTTTATCVRATGRSPCLTTRTALWSSTSW-LPPPSMASTRR 73
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000270776 | hsapiens_gene_ensembl |
6-phosphogluconate dehydrogenase, decarboxylating (EC 1.1.1.44).
[Source:Uniprot/SWISSPROT;Acc:P52209]
(514 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
02744 227 7e-60
00782 30 2.7
34301 30 3.4
>02744
Length = 3030
Score = 227 bits (579), Expect = 7e-60, Method: Compositional matrix adjust.
Identities = 101/146 (69%), Positives = 116/146 (79%)
Frame = -1
Query: 369 GFMLLRQAATEFGWTLNYGGIALMWRGGCIIRSVFLGKIKDAFDRNPELQNLLLDDFFKS 428
GFML+R+ A E GW LN G IALMWRGGCIIRSVFLG IK AFD NP+L NLLLD FFK
Sbjct: 3030 GFMLMRETAKELGWKLNMGAIALMWRGGCIIRSVFLGNIKQAFDNNPDLSNLLLDKFFKE 2851
Query: 429 AVENCQDSWRRAVSTGVQAGIPMPCFTTALSFYDGYRHEMLPASLIQAQRDYFGAHTYEL 488
+ CQ+SWRR ++ V GIP P F+TAL+F+DGYR LPA+LIQAQRDYFGAHTYE
Sbjct: 2850 EIIKCQESWRRVMAQAVTLGIPTPAFSTALAFFDGYRSASLPANLIQAQRDYFGAHTYER 2671
Query: 489 LAKPGQFIHTNWTGHGGTVSSSSYNA 514
L PG+F+HTNWTGHGG VSS++Y A
Sbjct: 2670 LDNPGKFVHTNWTGHGGNVSSTTYQA 2593
>00782
Length = 1035
Score = 29.6 bits (65), Expect = 2.7, Method: Compositional matrix adjust.
Identities = 11/33 (33%), Positives = 21/33 (63%)
Frame = +3
Query: 240 LGMAQDEMAQAFEDWNKTELDSFLIEITANILK 272
+GM ++++ Q +ED ++E+ F EI + I K
Sbjct: 279 MGMNEEDLKQKYEDQLQSEMSGFEYEIVSRIFK 377
>34301
Length = 429
Score = 29.6 bits (65), Expect = 3.4, Method: Composition-based stats.
Identities = 26/113 (23%), Positives = 45/113 (39%), Gaps = 8/113 (7%)
Frame = -1
Query: 374 RQAATEFGWTLNYGGIALMWRGGCIIRSVFLGKIKDAFDRNPELQNLLLDDFFKSAVEN- 432
R + + + +N + L R G + FL I + F R E +++ + + N
Sbjct: 408 RLPSASYHYLVNAFPVILPPRWGTETSAAFLVNIDNQFVRPAEALQFMVERSERQILSNS 229
Query: 433 -------CQDSWRRAVSTGVQAGIPMPCFTTALSFYDGYRHEMLPASLIQAQR 478
C DS R +T V+A PC TT + + + P S+ +R
Sbjct: 228 STPSTPCCLDSSRTTTATCVRATGRSPCLTTRTALWSSTSW-LPPPSMASTRR 73
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000313950 | hsapiens_gene_ensembl |
Serine/threonine-protein kinase 12 (EC 2.7.11.1) (Aurora-B) (Aurora-
and Ipl1-like midbody-associated protein 1) (AIM-1) (Aurora/IPL1-
related kinase 2) (Aurora-related kinase 2) (STK-1).
[Source:Uniprot/SWISSPROT;Acc:Q96GD4]
(344 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
21433 158 3e-59
15910 102 2e-22
30755 100 1e-21
12721 99 3e-21
03240 96 2e-20
18484 92 2e-19
14420 87 1e-17
18921 87 1e-17
14126 84 7e-17
00486 82 2e-16
01756 82 3e-16
01707 82 4e-16
01060 81 5e-16
00300 78 5e-15
09606 77 9e-15
06405 77 1e-14
13592 75 4e-14
01718 73 2e-13
09007 72 3e-13
21079 71 7e-13
25019 53 8e-13
04591 70 1e-12
13066 69 3e-12
01392 68 5e-12
20152 68 5e-12
27546 67 9e-12
17975 67 1e-11
18663 66 2e-11
31885 66 2e-11
26009 45 1e-09
14116 58 5e-09
26560 57 8e-09
11780 55 1e-08
13212 57 1e-08
01966 55 3e-08
07940 55 3e-08
19094 55 6e-08
17722 54 7e-08
26711 53 1e-07
29581 53 2e-07
19301 52 3e-07
04852 52 5e-07
38560 51 5e-07
27405 51 6e-07
14477 51 8e-07
27274 50 1e-06
20559 47 3e-06
21808 49 3e-06
19761 48 5e-06
04138 46 2e-05
28157 45 3e-05
12672 45 4e-05
37602 37 6e-05
00715 44 1e-04
32957 43 2e-04
03508 42 5e-04
32359 42 5e-04
07833 40 0.002
11185 39 0.003
03106 39 0.003
07291 39 0.004
29590 39 0.004
12786 38 0.008
02638 36 0.017
31489 34 0.070
00638 34 0.098
28638 33 0.13
20655 33 0.14
36002 32 0.27
31120 32 0.47
18401 31 0.69
33586 30 1.3
16708 30 1.4
18481 30 1.7
21418 29 2.9
00409 29 3.2
14104 28 7.7
20513 27 9.8
16350 27 9.8
>21433
Length = 590
Score = 158 bits (399), Expect(2) = 3e-59, Method: Compositional matrix adjust.
Identities = 77/136 (56%), Positives = 90/136 (66%)
Frame = +2
Query: 175 QRTATIMEELADALMYCHGKKVIHRDIKPXXXXXXXXXXXXIADFGWSVHAPSLRRKTMC 234
+RTA + +L+ AL YCH +KVIHRDIKP IADFGWSVHAPS RR TMC
Sbjct: 167 KRTACYIYQLSSALEYCHYRKVIHRDIKPENLLLGLKGDLKIADFGWSVHAPSSRRTTMC 346
Query: 235 GTLDYLPPEMIEGRMHNEKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPA 294
GTLDYLPPEM+EG+ H+E VDLW +GVLCYE LVG PP + + P+
Sbjct: 347 GTLDYLPPEMVEGKTHDENVDLWSLGVLCYEFLVGTPPLRPSPTRPPTPASPRWTSGSPS 526
Query: 295 SVPMGAQDLISKLLRH 310
V GA+DLISKLLRH
Sbjct: 527 IVTPGARDLISKLLRH 574
Score = 89.0 bits (219), Expect(2) = 3e-59, Method: Compositional matrix adjust.
Identities = 40/61 (65%), Positives = 49/61 (80%)
Frame = +3
Query: 120 HQLRREIEIQAHLHHPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTAT 179
HQLRREIEIQ+HL H NILR++ YF+D+ R+YLILE+AP+GELYKELQ+ FDE
Sbjct: 3 HQLRREIEIQSHLRHDNILRMFGYFHDKTRVYLILEFAPKGELYKELQRCHKFDENEQHA 182
Query: 180 I 180
I
Sbjct: 183 I 185
>15910
Length = 1361
Score = 102 bits (254), Expect = 2e-22, Method: Compositional matrix adjust.
Identities = 55/177 (31%), Positives = 91/177 (51%), Gaps = 8/177 (4%)
Frame = +2
Query: 161 ELYKELQKSCTFDEQRTATIMEELADALMYCHGKKVIHRDIKPXXXX---XXXXXXXXIA 217
EL+ + + E+ A + ++ + Y H V+HRD+KP +A
Sbjct: 422 ELFDRIVTRGQYTEKDAARAISDILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLA 601
Query: 218 DFGWS-VHAPSLRRKTMCGTLDYLPPEMIEGRMHNEKVDLWCIGVLCYELLVGNPPFESA 276
DFG S + P ++ T+CGT Y PE+++G + VD+W +GV+ Y LL G PF +
Sbjct: 602 DFGLSRIIEPEVQMSTVCGTPGYCAPEVLKGDKYTPSVDMWSVGVIAYILLCGYEPFFAE 781
Query: 277 SHNETYRRIVKVDLKFP----ASVPMGAQDLISKLLRHNPSERLPLAQVSAHPWVRA 329
+ E YR+I+K + KF + + A+D++ KLL +P +RL + PWV+
Sbjct: 782 NEFEMYRKIIKGEYKFDEEYWSEISENAKDVVRKLLVIDPKKRLTATEALRLPWVKG 952
>30755
Length = 1137
Score = 100 bits (248), Expect = 1e-21, Method: Compositional matrix adjust.
Identities = 58/179 (32%), Positives = 88/179 (49%), Gaps = 13/179 (7%)
Frame = +2
Query: 172 FDEQRTATIMEELADALMYCHGKKVIHRDIKPXXXXXXXXXXXXIADFGWSVHAPSLRR- 230
F E+RT E+ AL Y H + +I+RD+K +ADFG + R
Sbjct: 23 FTEERTRFYGAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCKEDITYGRT 202
Query: 231 -KTMCGTLDYLPPEMIEGRMHNEKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVD 289
KT CGT +YL PE+++ + VD W GV+ YE++ G PF + H+ + I+ D
Sbjct: 203 TKTFCGTPEYLAPEVLDDNDYGRAVDWWGTGVVMYEMICGRLPFYNRDHDVLFTLILVED 382
Query: 290 LKFPASVPMGAQDLISKLLRHNPSERLPLAQ-----VSAHP------WVRANSRRVLPP 337
+KFP ++ A+ L+S LL +P RL Q + AHP W +++ PP
Sbjct: 383 VKFPRNITDEAKSLLSGLLAKDPRNRLGGGQDDVKEIQAHPFFASINWTDLVQKKITPP 559
>12721
Length = 821
Score = 98.6 bits (244), Expect = 3e-21, Method: Compositional matrix adjust.
Identities = 64/247 (25%), Positives = 115/247 (46%), Gaps = 5/247 (2%)
Frame = +1
Query: 74 IDDFEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLH 133
+DDF +G+G G V +A + + K+ + Q +E L E+ + H
Sbjct: 94 LDDF---MKIGEGSTGIVCIATSRDGRQMAVKKMDLRKQQRRE----LLFNEVVVMRDYH 252
Query: 134 HPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYCHG 193
HPNI+ +YN + +++++E+ G L ++ + DE + AT+ AL + H
Sbjct: 253 HPNIVEMYNSYLVNDELWVVMEFMEGGAL-TDIVTNNRMDEVQIATVCRACLKALAFLHA 429
Query: 194 KKVIHRDIKPXXXXXXXXXXXXIADFGWSVHAPS--LRRKTMCGTLDYLPPEMIEGRMHN 251
VIHRDIK + DFG+ +RK++ GT ++ PE+I +
Sbjct: 430 NGVIHRDIKSDSILLSHDGKVKLXDFGFCAQVTQDLQKRKSLVGTPYWMAPEVISRLPYG 609
Query: 252 EKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKV---DLKFPASVPMGAQDLISKLL 308
+VD+W +G++ E++ PPF + + RRI + L+ + Q I ++L
Sbjct: 610 PEVDIWSLGIMVMEMIDAEPPFFNEPPLQAMRRIRDMPPPKLRNTHKISPRLQGFIDRML 789
Query: 309 RHNPSER 315
+P +R
Sbjct: 790 VRDPHQR 810
>03240
Length = 1683
Score = 95.9 bits (237), Expect = 2e-20, Method: Compositional matrix adjust.
Identities = 79/283 (27%), Positives = 126/283 (44%), Gaps = 52/283 (18%)
Frame = -3
Query: 77 FEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLHHPN 136
FE + LG G FG V L R+ + + A+K L KS + K ++ E +I A +
Sbjct: 1285 FEKIKTLGVGAFGEVSLCRKNDTGMLYAMKTLRKSDVLKRNQVAHVKAERDILAEADNEW 1106
Query: 137 ILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYCHGKKV 196
+++LY F D +Y +++Y P G+L L + DE + EL A+ H
Sbjct: 1105 VVKLYYSFQDHNYLYFVMDYVPGGDLMGLLIRMEILDEPLARFYVAELVQAIESVHRMGF 926
Query: 197 IHRDIKPXXXXXXXXXXXXIADFG------WS----------VHA--------------- 225
IHRDIKP + DFG W+ HA
Sbjct: 925 IHRDIKPDNILIDRNGHIKLTDFGLCTGFRWTHNSKYYQRDGTHARQDSMEVKCQLDEQC 746
Query: 226 ------PSLRRK---------TMCGTLDYLPPEMIEGRM--HNEKVDLWCIGVLCYELLV 268
P RR+ ++ GT +Y+ PE++ R+ + D W +GV+ +E+LV
Sbjct: 745 QCEILKPLERRRKREQRCLAHSLVGTPNYIAPEVL-SRLGGYTSVCDWWSVGVILFEMLV 569
Query: 269 GNPPFESASHNETYRRIV--KVDLKFP--ASVPMGAQDLISKL 307
G+PPF + + ET +++ K LK P +++ A+DLI +L
Sbjct: 568 GHPPFYANTPAETQYKVINWKDMLKIPRESNLSQPAKDLILRL 440
>18484
Length = 635
Score = 92.4 bits (228), Expect = 2e-19, Method: Compositional matrix adjust.
Identities = 55/183 (30%), Positives = 85/183 (46%), Gaps = 3/183 (1%)
Frame = +1
Query: 161 ELYKELQKSCTFDEQRTATIMEELADALMYCHGKKVIHRDIKPXXXXXXXXXXXXIADFG 220
+L +Q+ F E A E+A L + H + +I+RD+K IADFG
Sbjct: 1 DLMYRIQQEGKFKEPVAAFYAAEIAVGLFFLHDQGIIYRDLKLDNVMLDSEGHIKIADFG 180
Query: 221 WSVHAPS--LRRKTMCGTLDYLPPEMIEGRMHNEKVDLWCIGVLCYELLVGNPPFESASH 278
+ +T CGT DY+ PE++ + +++ VD W GVL +E+L G PPF+
Sbjct: 181 MCKEGMTGDATTRTFCGTPDYIAPEIVLYQPYSKSVDWWAYGVLLFEMLAGQPPFDGEDE 360
Query: 279 NETYRRIVKVDLKFPASVPMGAQDLISKLLRHNPSERLPLAQVSAHPW-VRANSRRVLPP 337
+E + I ++ +P ++ A L LL NP++RL W R R LP
Sbjct: 361 DELFSSITDHNVSYPKAMSREAVSLCKGLLMKNPTKRLGCGS----KW*TRHQRPRFLPT 528
Query: 338 SAL 340
L
Sbjct: 529 DCL 537
>14420
Length = 528
Score = 87.0 bits (214), Expect = 1e-17, Method: Compositional matrix adjust.
Identities = 43/152 (28%), Positives = 76/152 (50%), Gaps = 2/152 (1%)
Frame = +2
Query: 124 REIEIQAHLHHPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEE 183
EI + +PNI+ + + +++++E+ G L + ++C DE + A + E
Sbjct: 47 NEILVMRENQNPNIVNYLDSYLVGEELWVVMEFLAGGSLTDVVTETC-MDEGQIAAVCRE 223
Query: 184 LADALMYCHGKKVIHRDIKPXXXXXXXXXXXXIADFGWSVHAP--SLRRKTMCGTLDYLP 241
AL + H +VIHRDIK + DFG+ +R TM GT ++
Sbjct: 224 CLQALEFLHENQVIHRDIKSDNILLGMDGSVKLTDFGFCAQLSPEQSKRSTMVGTPYWMA 403
Query: 242 PEMIEGRMHNEKVDLWCIGVLCYELLVGNPPF 273
PE++ + + VD+W +GV+C E++ G PP+
Sbjct: 404 PEVVTRKQYGPTVDIWSLGVMCIEMIEGEPPY 499
>18921
Length = 697
Score = 86.7 bits (213), Expect = 1e-17, Method: Compositional matrix adjust.
Identities = 53/206 (25%), Positives = 101/206 (49%), Gaps = 3/206 (1%)
Frame = +2
Query: 75 DDFEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLHH 134
D F+I LG+G +G+V+ + K++ ++A+K Q+ + ++ +EI I
Sbjct: 29 DVFDILGKLGEGSYGSVFKSLHKETGQVLAIK-----QVPVDTDLQEIIKEISIMQQCDS 193
Query: 135 PNILRLYNYFYDRRRIYLILEYAPRGELYKELQ-KSCTFDEQRTATIMEELADALMYCHG 193
I++ Y ++ +++++EY G + ++ ++ T E+ ATI+ L Y H
Sbjct: 194 KYIVKYYGSYFKNTDLWIVMEYCGAGSVSDIMRLRNKTLVEREIATILYYTLKGLXYLHS 373
Query: 194 KKVIHRDIKPXXXXXXXXXXXXIADFGWSVHAPSL--RRKTMCGTLDYLPPEMIEGRMHN 251
++ IHRDIK +ADFG + +R T+ GT ++ PE+I+ ++
Sbjct: 374 RRKIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTPYWMAPEVIQEIGYD 553
Query: 252 EKVDLWCIGVLCYELLVGNPPFESAS 277
D+W +G+ E+ G PP S
Sbjct: 554 CVADIWSLGITALEMAEGKPPVMETS 631
>14126
Length = 1265
Score = 84.3 bits (207), Expect = 7e-17, Method: Compositional matrix adjust.
Identities = 77/299 (25%), Positives = 132/299 (44%), Gaps = 39/299 (13%)
Frame = +3
Query: 83 LGKGKFGNVYLAREKKSHF-IVALKVLFKSQIEKEGVEHQLRREIEIQAHLH---HPNIL 138
+G G +G VY AR+ ++ VA+K + + E EG+ REI + L HPN++
Sbjct: 213 IGNGAYGTVYKARDLRNQGEFVAMKRIRLNNTE-EGMPMMAIREISMLKQLEQYEHPNVV 389
Query: 139 RL----YNYFYDRR-RIYLILEYAPRGELYKELQK--SCTFDEQRTATIMEELADALMYC 191
RL +N DR R+ L+ EY +L L K S R +M +L + + +
Sbjct: 390 RLLDVSHNTITDREIRLNLVFEYIEH-DLATYLAKCPSPGLGPDRIKDLMLQLLNGVDFL 566
Query: 192 HGKKVIHRDIKPXXXXXXXXXXXXIADFGWS-VHAPSLRRKTMCGTLDYLPPEMIEGRMH 250
H +++HRD+KP +ADFG + +++ + T+ TL Y PE++ +
Sbjct: 567 HSNRIVHRDLKPQNLLISKDGRLKLADFGLARIYSFHMALTTVVVTLWYRSPEVLMQAEY 746
Query: 251 NEKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPAS--------------- 295
VD+W G + EL F+ +S + ++I +V PA
Sbjct: 747 GTSVDIWSCGCIFAELFTRRALFKGSSEFDQLKKIFEVIGLPPAGDWPEGVSVHRNSFRP 926
Query: 296 ---VPM---------GAQDLISKLLRHNPSERLPLAQVSAHPWVRANSRRVLPPSALQS 342
VP+ A+DL+ K+L R+ + HP++R + + S+L +
Sbjct: 927 TPPVPLQTLVPEMDPQAKDLMEKMLVFKSGRRISSRESLLHPYLRDDLDSIRTSSSLST 1103
>00486
Length = 797
Score = 82.4 bits (202), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 42/117 (35%), Positives = 61/117 (52%), Gaps = 11/117 (9%)
Frame = -2
Query: 232 TMCGTLDYLPPEMIEGRMHNEKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLK 291
T CGT++Y+ PE++ H + VD W +G L Y++L G+PPF + + +T +I+K L
Sbjct: 781 TFCGTIEYMAPEILTRTGHGKAVDWWSLGALMYDMLTGSPPFTAENRKKTIDKILKGKLN 602
Query: 292 FPASVPMGAQDLISKLLRHNPSERLPLAQVSAHP-----------WVRANSRRVLPP 337
P + A+ LI KLLR NP+ERL + P W RR PP
Sbjct: 601 LPPYLTNEARGLIKKLLRKNPAERLGGGHDDSGPIKDHQFFRNTNWALLALRRAEPP 431
>01756
Length = 1858
Score = 82.0 bits (201), Expect = 3e-16, Method: Compositional matrix adjust.
Identities = 62/220 (28%), Positives = 98/220 (44%), Gaps = 14/220 (6%)
Frame = -3
Query: 83 LGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLHHPNILRLYN 142
+G+G FG V+ AR KK+ +VA+K + EKEG REI+I L+H N++ L
Sbjct: 1718 IGQGTFGEVFKARCKKTKQVVAMKKVLMDN-EKEGFPITALREIKILQLLNHENVVDLIE 1542
Query: 143 YFYDR--------RRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYCHGK 194
+ YL+ E+ S F+ +M++L + L Y H
Sbjct: 1541 ICSTKATSANRYKSMFYLVFEFCEHDLAGLLSNMSVVFNLPEIKEVMKQLMNGLYYIHRN 1362
Query: 195 KVIHRDIKPXXXXXXXXXXXXIADFG----WSVHAPSLRRKT-MCGTLDYLPPEMIEG-R 248
K++HRD+K +ADFG +SV+ R T TL Y PPE++ G R
Sbjct: 1361 KILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRPPELLLGDR 1182
Query: 249 MHNEKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKV 288
++ +D W G + E+ NP + + I ++
Sbjct: 1181 NYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQNQLTLITQL 1062
>01707
Length = 757
Score = 81.6 bits (200), Expect = 4e-16, Method: Compositional matrix adjust.
Identities = 55/196 (28%), Positives = 95/196 (48%), Gaps = 3/196 (1%)
Frame = +1
Query: 78 EIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLHHPNI 137
+IG+ +G+G +G V+ R K++ +VA+K +S+ + ++ REI + L HPN+
Sbjct: 76 KIGK-IGEGSYGVVFKCRNKETSQLVAIKKFVESE-DDPLIKKIAMREIRMLKQLKHPNL 249
Query: 138 LRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYCHGKKVI 197
+RL F ++R++L+ +Y L + + E I+ + A+ +CH I
Sbjct: 250 VRLIEVFRRKKRLHLVFDYVDHTLLNELDRYPRGLPEPMVKRIIYQTLLAVNFCHQYNTI 429
Query: 198 HRDIKPXXXXXXXXXXXXIADFGWS--VHAPSLRRKTMCGTLDYLPPEMIEG-RMHNEKV 254
HRD+KP + DFG++ + P T Y PE++ G + V
Sbjct: 430 HRDVKPENILITRQGQVKLCDFGFARILTGPGDEYTDYVATRWYRAPELLVGDTQYGPPV 609
Query: 255 DLWCIGVLCYELLVGN 270
D+W IG + ELL G
Sbjct: 610 DVWAIGCVFAELLTGQ 657
>01060
Length = 1800
Score = 81.3 bits (199), Expect = 5e-16, Method: Compositional matrix adjust.
Identities = 55/220 (25%), Positives = 109/220 (49%), Gaps = 5/220 (2%)
Frame = +1
Query: 74 IDDFEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLH 133
+ D + +G+G +G VY R + + +A+K + + + ++GV REI + L
Sbjct: 70 LSDLTDFQKIGEGTYGVVYKCRHRATGRKLAMKKI-RLRGSEDGVPSSAIREIAMLRELR 246
Query: 134 HPNILRLYNYFYDRRRIYLILEYAPRG-ELY-KELQKSCTFDEQRTATIMEELADALMYC 191
H NI+ L + + R++L+ E+ ++Y + + D + + + ++ + +C
Sbjct: 247 HTNIVCLEDVIMEDERLFLVFEFLSMDLKMYIDKFPEGVVLDRRLVKSYVFQIVTGIXFC 426
Query: 192 HGKKVIHRDIKPXXXXXXXXXXXXIADFGWS-VHAPSLRRKTM-CGTLDYLPPEMIEG-R 248
H ++++HRD+KP IADFG + A +R T TL Y PE++ G
Sbjct: 427 HQRRIVHRDLKPQNLLINHTGAIKIADFGMARTFALPVRAYTHEVVTLWYRAPEILMGAS 606
Query: 249 MHNEKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKV 288
++ VD+W IG + ++L+ P F+ S + +I ++
Sbjct: 607 KYSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRI 726
>00300
Length = 2318
Score = 77.8 bits (190), Expect = 5e-15, Method: Compositional matrix adjust.
Identities = 60/261 (22%), Positives = 112/261 (42%), Gaps = 12/261 (4%)
Frame = -1
Query: 80 GRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLHHPNILR 139
G +G+G+FG VY A + ++ALK + K Q ++ EI+I + H N+++
Sbjct: 1643 GNKIGEGQFGKVYTAVNMSTGELMALKEM-KFQPNDLQQLREMCDEIKIFEGIQHENLVK 1467
Query: 140 LYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYCHGKKVIHR 199
Y + + + +EY G + E E E+ A+ + H ++HR
Sbjct: 1466 YYGVEVHKDEMLMFMEYCDTGTI--EEAAKMGLPEYLIRRYTREIVLAVNHLHENSIVHR 1293
Query: 200 DIKPXXXXXXXXXXXXIADFGWSVHAPSLRR-----KTMCGTLDYLPPEMI---EGRMHN 251
DIK + DFG SV S + GT Y+ PE+ + +
Sbjct: 1292 DIKGANIFLTSNGHVKLGDFGCSVKLKSHTTMPGEFHNLVGTTAYMAPEVFTQNDQGGYG 1113
Query: 252 EKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDL----KFPASVPMGAQDLISKL 307
D+W +G + E+ G P+ +N Y+ + KV + P S+ + + + +
Sbjct: 1112 RAADIWSLGCVVIEMATGKRPWHDLDNN--YQIMYKVGIGHKPAVPDSLSVEGKHFLDLI 939
Query: 308 LRHNPSERLPLAQVSAHPWVR 328
+ H+P++R +Q+ H + +
Sbjct: 938 MCHDPAQRALASQLLDHTFTK 876
>09606
Length = 1300
Score = 77.4 bits (189), Expect = 9e-15, Method: Compositional matrix adjust.
Identities = 59/298 (19%), Positives = 124/298 (41%), Gaps = 34/298 (11%)
Frame = -3
Query: 67 ILTRHFTIDDFEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREI 126
++TR +++F + LGKG+ +Y R K + VA+ + K + ++ +
Sbjct: 1130 LITR---MENFVLYEELGKGEHSIIYKGRRKGTINFVAIHCIEKCK------RPEVTNTV 978
Query: 127 EIQAHLHHPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELAD 186
+ + HPN+++ + ++ ++L++E G L L + E L
Sbjct: 977 RMTHDISHPNVVQFHEWYETSNHLWLVVELCTGGSLADILAQDHHLPETSIRDFGIHLVT 798
Query: 187 ALMYCHGKKVIHRDIKPXXXXXXXXXXXXIADFG----------------------WSVH 224
L Y H ++ D++P ADFG W++
Sbjct: 797 GLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQWNIQ 618
Query: 225 APS--LRRKTMCGTLDYLPPEMIEGRMHNEKVDLWCIGVLCYELLVGNPPFESASHNETY 282
+ +++ G+ Y+ PE+ +G + DLW +G + YE+ G+PPF +++ T
Sbjct: 617 SAEEMMKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSGHPPFLGETYDITK 438
Query: 283 RRIVKVDLKFPASVPMGAQ----------DLISKLLRHNPSERLPLAQVSAHPWVRAN 330
++ ++ +FP G++ +L+ LL+ + + RL A + H + +
Sbjct: 437 DKV--LNKEFPLPKVKGSRLSAKPSPEFLNLLESLLQKDSTRRLSWASLVKHAFWQGG 270
>06405
Length = 1965
Score = 76.6 bits (187), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 59/246 (23%), Positives = 102/246 (41%), Gaps = 7/246 (2%)
Frame = +1
Query: 83 LGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLHHPNILRLYN 142
LG G++G+VY A K+ + IVA+K L + + + E I + HPN+++L
Sbjct: 283 LGGGQYGDVYEAMWKRYNKIVAVKTLKEDTM----ALNDFLEEAAIMKEMKHPNLVQLLG 450
Query: 143 YFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTAT--IMEELADALMYCHGKKVIHRD 200
Y++ E+ P G L L+ S + TA + ++A + Y K IHRD
Sbjct: 451 VCTREPPFYIVTEFMPHGNLLDYLRSSTREENGPTALMYMATQIASGMAYLETKNFIHRD 630
Query: 201 IKPXXXXXXXXXXXXIADFGWSVHAPSLRRKTMCGT---LDYLPPEMIEGRMHNEKVDLW 257
+ +ADFG + G + + PE + + + D+W
Sbjct: 631 LAARNCLVADSNMVKVADFGLARLMKDDTYTAHIGAKFPIKWTAPEGLAFNRFSTRSDIW 810
Query: 258 CIGVLCYELLV-GNPPFESASHNETYRRIVK-VDLKFPASVPMGAQDLISKLLRHNPSER 315
GVL +EL G P+ E Y + + ++ P P L+ K + +P +R
Sbjct: 811 AFGVLLWELATYGMSPYPGVELTEVYHLLERGYRMERPPGTPADVYILMLKCWQWDPKDR 990
Query: 316 LPLAQV 321
++
Sbjct: 991 PTFKEI 1008
>13592
Length = 980
Score = 75.1 bits (183), Expect = 4e-14, Method: Compositional matrix adjust.
Identities = 56/261 (21%), Positives = 110/261 (42%), Gaps = 13/261 (4%)
Frame = +2
Query: 83 LGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLHHPNILRLYN 142
+G+G+FG VY A + ++A+K + E +++ + E++I + H N++R Y
Sbjct: 8 IGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETRALKN-VAEELKILEGIKHKNLVRYYG 184
Query: 143 YFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYCHGKKVIHRDIK 202
R + + +E G L ++ + E + +L + H ++HRDIK
Sbjct: 185 IEVHREELLIFMELCSEGTLESLVELTGGLPEALSRRFTAQLLSGVAELHKHGIVHRDIK 364
Query: 203 PXXX-XXXXXXXXXIADFGWSVHAPSLRR-----KTMCGTLDYLPPEMI---EGRMHNEK 253
+ DFG +V + + GT Y+ PE+ H
Sbjct: 365 TANIFLVDGSNSLKLGDFGSAVKIQAHTTVPGELQGYVGTQAYMAPEVFTKTNSDGHGRL 544
Query: 254 VDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDL----KFPASVPMGAQDLISKLLR 309
D+W +G + E+ G P+ A + ++ + KV + + P S+ D I L+
Sbjct: 545 ADIWSVGCVVVEMASGKRPW--AQFDSNFQIMFKVGMGEKPQAPESLSQEGHDFIDHCLQ 718
Query: 310 HNPSERLPLAQVSAHPWVRAN 330
H+P +RL ++ + ++
Sbjct: 719 HDPKQRLSAIELLEQNFCKSG 781
>01718
Length = 959
Score = 73.2 bits (178), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 59/210 (28%), Positives = 98/210 (46%), Gaps = 11/210 (5%)
Frame = +3
Query: 68 LTRHFTIDDFEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIE 127
LTR +DDF I +G G F V+ + + ++ALK+ + H + RE++
Sbjct: 138 LTR---LDDF-ICEKIGAGFFSEVFKVTHRITGQVMALKMNTMT-----SNRHNMLREVQ 290
Query: 128 IQAHLHHPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTAT----IMEE 183
+ L H NILR +++ + EY P G L + L+K DE+ T +
Sbjct: 291 LLNRLQHANILRFMGVCVHEGQLHALTEYIPSGNLEQLLEKK---DEELPWTQRIQLTLG 461
Query: 184 LADALMYCHGKKVIHRDIKPXXXXXXXXXX----XXIADFGWSVHAPS-LRRKTM--CGT 236
LA L Y H + IHRD+ IADFG + P L ++ + G+
Sbjct: 462 LARGLDYLHSTRFIHRDLTSKNILIRREDNHGYHAVIADFGLATKIPDPLDKEKLPTVGS 641
Query: 237 LDYLPPEMIEGRMHNEKVDLWCIGVLCYEL 266
++ PE++ G +NE+ DL+ +G++ E+
Sbjct: 642 PYWMAPEVLNGHFYNERADLFSVGIIMCEI 731
>09007
Length = 1440
Score = 72.0 bits (175), Expect = 3e-13, Method: Compositional matrix adjust.
Identities = 56/208 (26%), Positives = 84/208 (40%), Gaps = 14/208 (6%)
Frame = -1
Query: 75 DDFEIGRPLGKGKFGNVYLA---REKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAH 131
D + + LG+G FG V A E VA+K L K +I K+G E +E I
Sbjct: 879 DCVALSKSLGQGHFGTVRQAIWTAESGEKVQVAVKCLSKDKIHKDGQE--FLKETAIMQM 706
Query: 132 LHHPNILRLYNYFYDR-RRIYLILEYAPRG---ELYKELQKSCTFDEQRTATIMEELADA 187
L H NI+R+Y D I L+ E AP E KE+ F R +++ D
Sbjct: 705 LDHENIVRVYGVVMDNGADIMLVTELAPMRSLLECVKEVSARVDFSVPRLCDFSQQVCDG 526
Query: 188 LMYCHGKKVIHRDIKPXXXXXXXXXXXXIADFGWS-------VHAPSLRRKTMCGTLDYL 240
+ Y K+++HRD+ I+D G S + S + + + +
Sbjct: 525 MSYLESKRLVHRDLAARNILLFSKSKVKISDVGVSGALGAGKEYYQSQQTIHLQNAVAWC 346
Query: 241 PPEMIEGRMHNEKVDLWCIGVLCYELLV 268
PE + D+W GVL +E
Sbjct: 345 APESFRNLCFSSASDVWAFGVLLWEFFT 262
>21079
Length = 878
Score = 70.9 bits (172), Expect = 7e-13, Method: Compositional matrix adjust.
Identities = 39/143 (27%), Positives = 70/143 (48%), Gaps = 4/143 (2%)
Frame = +1
Query: 134 HPNILRLYNYFYDRRRIYLILEYAPRGELYKE-LQKSCTFDEQRTATIMEELADALMYCH 192
HP +L L++ F R + L++E+ GEL++ ++ E+ + ++ + Y H
Sbjct: 1 HPKLLMLWDAFEAPRTMVLVMEFVGAGELFERVIRDDFVLTERDCVHFVRQICSGVGYMH 180
Query: 193 GKKVIHRDIKPXXXXXXX--XXXXXIADFGWS-VHAPSLRRKTMCGTLDYLPPEMIEGRM 249
+ ++H D+KP I DFG + + P + + GT +++ PE++
Sbjct: 181 TQSILHLDLKPENVLCVSDNSNQIKIIDFGLARFYKPGDSLQVLFGTPEFIAPEVVNYDE 360
Query: 250 HNEKVDLWCIGVLCYELLVGNPP 272
N D+W IGV+CY LL G P
Sbjct: 361 INFTTDMWSIGVICYILLSGLSP 429
>25019
Length = 730
Score = 53.1 bits (126), Expect(2) = 8e-13, Method: Compositional matrix adjust.
Identities = 25/57 (43%), Positives = 36/57 (63%)
Frame = +1
Query: 260 GVLCYELLVGNPPFESASHNETYRRIVKVDLKFPASVPMGAQDLISKLLRHNPSERL 316
G L Y++L G+PPF + + +T +I+K L P + A+ LI KLLR NP+ERL
Sbjct: 436 GALMYDMLTGSPPFTAENRKKTIDKILKGKLNLPPYLTNEARGLIKKLLRKNPAERL 606
Score = 37.7 bits (86), Expect(2) = 8e-13, Method: Compositional matrix adjust.
Identities = 17/47 (36%), Positives = 26/47 (55%), Gaps = 2/47 (4%)
Frame = +3
Query: 216 IADFGWSVHAPSLRR--KTMCGTLDYLPPEMIEGRMHNEKVDLWCIG 260
+ DFG A + R T CGT++Y+ PE++ H + VD W +G
Sbjct: 297 LTDFGLCKEAITGTRVTHTFCGTIEYMAPEILTRTGHGKAVDWWSLG 437
>04591
Length = 1117
Score = 70.1 bits (170), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 68/277 (24%), Positives = 113/277 (40%), Gaps = 48/277 (17%)
Frame = -2
Query: 115 KEGVEHQLRREIEIQAHLHHPNILRL----------YNYFYDRRRIYLILEYAPR--GEL 162
KEG REI+I L H N+++L YN + + YLI EY L
Sbjct: 1101 KEGFPITALREIKILQQLEHENVVQLQEICHTQAGPYNRY--KSTFYLIFEYCDYDLAGL 928
Query: 163 YKELQKSCTFDEQRTATIMEELADALMYCHGKKVIHRDIKPXXXXXXXXXXXXIADFGWS 222
L+ + +++ +M +L + L Y H K+++HRDIK +ADFG S
Sbjct: 927 LNNLRVKFSLADKKN--LMSQLLNGLFYIHTKQILHRDIKAANILLTRDGVLKLADFGLS 754
Query: 223 VHAPSLRRKTMCG---TLDYLPPEMIEG-RMHNEKVDLWCIGVLCYELLVGNPPFESASH 278
P ++ K + TL Y PPE++ G R + ++D+W +G + E+ P + S
Sbjct: 753 --RPWVKSKRLTNRVVTLWYRPPELLLGEREYGPEIDMWGVGCIMAEMWSRKPLMQGRSE 580
Query: 279 N---------------ETYRRIVKVDLKFPASVPMG-----------------AQDLISK 306
E + + K++L +P G +LI
Sbjct: 579 QHQLSLITDLCGSLNAEVWPGVTKLELYGKLDLPQGKPRKVKERMLDLLKNKEGAELIDI 400
Query: 307 LLRHNPSERLPLAQVSAHPWVRANSRRVLPPSALQSV 343
LR +P +R+ +H + + LP +L S+
Sbjct: 399 FLRLDPGQRMNCDNALSHDFFWVDP---LPSPSLTSI 298
>13066
Length = 551
Score = 68.9 bits (167), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 42/164 (25%), Positives = 78/164 (47%), Gaps = 6/164 (3%)
Frame = +3
Query: 103 VALKVLFKSQIEKEGVEHQLRREIEIQAHLHHPNILRLYNYFYDRRRIYLILEYAPRGEL 162
+A K++ K + + VE RE+++ L HP I+++++ + ++ + +A RG+L
Sbjct: 60 LACKIIDKEKAPVDFVEKFFPRELDLLTKLDHPYIIQIHSILQRXPKNFIFMRFAERGDL 239
Query: 163 YKELQKSCTFDEQRTATIMEELADALMYCHGKKVIHRDIKPXXXXXXXXXXXXIADFGWS 222
+Q+ E++ ++ AL Y H V HRD+K +ADFG++
Sbjct: 240 LTYIQEVGFVKEKQAKIWFYQMTTALNYLHSYDVAHRDLKCENILLSSHFNVKLADFGFA 419
Query: 223 VHAPS-----LRRKTMCGTLDYLPPEMIEGRMHNEKV-DLWCIG 260
+ +T CG+ Y PE++ G + KV D W +G
Sbjct: 420 CACITESGEKYMSRTYCGSAAYAAPEIVYGAPYAPKVADAWSLG 551
>01392
Length = 1806
Score = 68.2 bits (165), Expect = 5e-12, Method: Compositional matrix adjust.
Identities = 56/204 (27%), Positives = 87/204 (42%), Gaps = 36/204 (17%)
Frame = -1
Query: 174 EQRTATIMEELADALMYCHGKKVIHRDIKPXXXXXXXXXXX---XIADF---------GW 221
E+ + ++ +A AL + H K + HRD+KP I DF G
Sbjct: 1794 EREASLVVRHIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGISCDGD 1615
Query: 222 SVHAPSLRRKTMCGTLDYLPPEMIEGRM-----HNEKVDLWCIGVLCYELLVGNPPFES- 275
P L T G+ +Y+ PE+++ + ++++ DLW +G++ Y +L G PPF
Sbjct: 1614 GTKTPELL--TPVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILYIMLCGYPPFYGQ 1441
Query: 276 -----------ASH---NETYRRIVKVDLKFPA----SVPMGAQDLISKLLRHNPSERLP 317
A H + + I KFP+ S+ A+DLI LL P +R
Sbjct: 1440 CGEDCGWNRGEACHDCQDMLFNSIQDGHYKFPSQEWTSISSSAKDLIRHLLVREPRKRYS 1261
Query: 318 LAQVSAHPWVRANSRRVLPPSALQ 341
A V HPW+ PP+A Q
Sbjct: 1260 AADVLKHPWI------CTPPAATQ 1207
>20152
Length = 445
Score = 68.2 bits (165), Expect = 5e-12, Method: Compositional matrix adjust.
Identities = 35/99 (35%), Positives = 56/99 (56%), Gaps = 1/99 (1%)
Frame = +1
Query: 242 PEMIEGRMHNE-KVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPASVPMGA 300
PE++ G ++ VD+W +GV+ Y L+VG PF+ A+ +ET I+ + P +
Sbjct: 1 PEILLGDSYDAPAVDVWSLGVILYMLVVGEAPFQEANDSETLTMIMDCRYQIPPHISHKC 180
Query: 301 QDLISKLLRHNPSERLPLAQVSAHPWVRANSRRVLPPSA 339
QDLI K+L+ P +R L + AHPW+ N + P +A
Sbjct: 181 QDLIEKMLQREPVDRASLPHILAHPWL--NDGDLTPTTA 291
>27546
Length = 426
Score = 67.4 bits (163), Expect = 9e-12, Method: Compositional matrix adjust.
Identities = 35/120 (29%), Positives = 65/120 (54%)
Frame = -1
Query: 103 VALKVLFKSQIEKEGVEHQLRREIEIQAHLHHPNILRLYNYFYDRRRIYLILEYAPRGEL 162
+A K++ K++ + V+ RE+EI L HPNI+++++ +I++ + YA +G++
Sbjct: 396 LACKIIDKAKAPIDFVKKFFPRELEILTRLDHPNIIQIHSILQRGPKIFIFMRYAEKGDM 217
Query: 163 YKELQKSCTFDEQRTATIMEELADALMYCHGKKVIHRDIKPXXXXXXXXXXXXIADFGWS 222
++K+ DE +T ++A AL Y H + HRD+K IADFG++
Sbjct: 216 LSHIKKTGPIDEAQTKVWFFQMAKALQYLHSHDIAHRDLKCENILLSKRLNVKIADFGFA 37
>17975
Length = 449
Score = 67.0 bits (162), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 42/137 (30%), Positives = 72/137 (52%), Gaps = 2/137 (1%)
Frame = +3
Query: 88 FGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLHHPNILRLYNYFYDR 147
F V LAR + VA+KV+ K+++++ H L +E+ + HPN++RLY +
Sbjct: 6 FAVVKLARHVFTGEKVAVKVIDKTKLDEVSRSH-LFQEVRCMKLVQHPNVVRLYEVIDTQ 182
Query: 148 RRIYLILEYAPRGELYKELQK-SCTFDEQRTATIMEELADALMYCHGKKVIHRDIKPXXX 206
++YLILE G++Y + + S +E+ ++ +A+ YCH V+HRD+KP
Sbjct: 183 TKLYLILELGDGGDMYDYIMRHSGGLEEKLAKRYFRQIVEAISYCHKLHVVHRDLKPENV 362
Query: 207 XXXXX-XXXXIADFGWS 222
+ DFG+S
Sbjct: 363 VFFEKPGLVKLTDFGFS 413
>18663
Length = 600
Score = 66.2 bits (160), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 39/127 (30%), Positives = 63/127 (49%), Gaps = 21/127 (16%)
Frame = +2
Query: 232 TMCGTLDYLPPEMIEGRMHNEKVDLWCIGVLCYELLVGNPPFESASHNET---------Y 282
T CGT +Y+ PE++ G + VD W +GVL YE+L G PF+ A +E +
Sbjct: 5 TFCGTPNYIAPEILRGEDYGFSVDWWALGVLLYEMLAGRSPFDIAGASENPDQNTEDYLF 184
Query: 283 RRIVKVDLKFPASVPMGAQDLISKLLRHNPSERLPLAQVSA------HP------WVRAN 330
+ I++ ++ P S+ + A ++ L NP++RL + SA HP W
Sbjct: 185 QVILEKTIRIPRSLSVKAASVLKGFLNKNPADRLGCHRESAFMDIVNHPFFKVIDWEMLE 364
Query: 331 SRRVLPP 337
++V PP
Sbjct: 365 RKQVSPP 385
>31885
Length = 529
Score = 66.2 bits (160), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 43/160 (26%), Positives = 72/160 (45%), Gaps = 6/160 (3%)
Frame = -2
Query: 126 IEIQAHLHHPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELA 185
+++ L HP ++ L+ F D ++++++ G+L +Q+ +F E + +LA
Sbjct: 519 VDMLTRLDHPFLVNLWYAFQDEEDLFMVVDLFLGGDLRYHMQQEVSFREDCVKFYLCQLA 340
Query: 186 DALMYCHGKKVIHRDIKPXXXXXXXXXXXXIADFGWSVHAPSLRRKT-MCGTLDYLPPEM 244
L Y +K++HRDIKP + DF + T GT Y+ PE+
Sbjct: 339 LVLDYLRSQKIVHRDIKPDNILLDEQGHCHVTDFNIATQLEDDELATSTSGTRPYMAPEV 160
Query: 245 I-----EGRMHNEKVDLWCIGVLCYELLVGNPPFESASHN 279
E R + VD W +GV +ELL PF S+
Sbjct: 159 YGVAINERRGYGFPVDWWSLGVSLFELLKKRRPFSVHSNT 40
>26009
Length = 886
Score = 44.7 bits (104), Expect(2) = 1e-09, Method: Compositional matrix adjust.
Identities = 29/92 (31%), Positives = 50/92 (54%), Gaps = 2/92 (2%)
Frame = +2
Query: 77 FEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLH-HP 135
+++ + LG+G +G V LAR + + VALK+L KS + + +RE ++ L H
Sbjct: 422 YDVCKELGRGTYGKVVLARCRHTGTQVALKLLPKSCTKL----REFQREFQLSYFLSPHA 589
Query: 136 NILRLYNYFYDRRRIYLIL-EYAPRGELYKEL 166
NI+ YN + R Y+ E+A G+L+ +
Sbjct: 590 NIIDTYNVAFQTRSSYVFAQEHAVLGDLFDAI 685
Score = 35.4 bits (80), Expect(2) = 1e-09, Method: Compositional matrix adjust.
Identities = 15/37 (40%), Positives = 25/37 (67%)
Frame = +3
Query: 167 QKSCTFDEQRTATIMEELADALMYCHGKKVIHRDIKP 203
K+C E ++ +M++L AL + H K+++HRDIKP
Sbjct: 693 NKACGSREAKS--VMKQLVSALDFMHSKQLVHRDIKP 797
>14116
Length = 1017
Score = 58.2 bits (139), Expect = 5e-09, Method: Compositional matrix adjust.
Identities = 73/298 (24%), Positives = 118/298 (39%), Gaps = 33/298 (11%)
Frame = -1
Query: 3 QKENSYPWPYGRQTAPSGLSTLPQRVLRKEPVTPSALVLMSRSNVQPTAA--------PG 54
++E S + G Q G+ + R E +R +VQ A
Sbjct: 846 EQEPSIAYTAGHQVGIDGVDSNGTRTYNLEARENDYF---NRLDVQGAEAMPLLHIDEDM 676
Query: 55 QKVMENSSGTPDILTRHFTIDDFEIGRPLGKGKFGNV---YLAR-EKKSHFIVALKVLFK 110
K++EN S D R F +G +GKG FG V +L E+K +VA+K L
Sbjct: 675 MKLIENESLLID---REF----LTMGEEIGKGNFGCVKRGFLTLPEQKGDILVAVKTLHN 517
Query: 111 SQIEKEGVEHQLRREIEIQAHL---------HHPNILRLYNYFYDRRRI-YLILEYAPRG 160
+ REIE+Q+ L HH N+L L + + ++L + G
Sbjct: 516 NN----------PREIELQSFLQEALIMKDFHHSNVLTLIGICLNLDDMPLVVLPFMKHG 367
Query: 161 ELYKELQKSCTFDEQRTATIME------ELADALMYCHGKKVIHRDIKPXXXXXXXXXXX 214
+L ++ D+Q TI + ++A + Y G K +HRD+
Sbjct: 366 DLLTYIR-----DDQHQPTIKDLIMYGVDIARGMDYLAGLKFVHRDLAARNCMLDEDFHV 202
Query: 215 XIADFG-----WSVHAPSLRRKTMCGTLDYLPPEMIEGRMHNEKVDLWCIGVLCYELL 267
+ADFG + S K + ++ E +E ++ K D+W GV+ +ELL
Sbjct: 201 KVADFGLARDIYEKEYYSSENKKAKLPVKWMALESLEKGNYDSKTDVWSYGVVLWELL 28
>26560
Length = 398
Score = 57.4 bits (137), Expect = 8e-09, Method: Compositional matrix adjust.
Identities = 34/131 (25%), Positives = 61/131 (46%), Gaps = 1/131 (0%)
Frame = -1
Query: 161 ELYKELQKSCTFDEQRTATIMEELADALMYCHGKKVIHRDIKPXXXXXXXXXXXXIADFG 220
+L+ L + F E+ E+ L + H + V++RD+KP I+D G
Sbjct: 398 DLHYHLSQHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLG 219
Query: 221 WSVHAPSLRRKTMCGTLDYLPPE-MIEGRMHNEKVDLWCIGVLCYELLVGNPPFESASHN 279
+ R GT Y+ PE +++G+ ++ D + G + Y+LL G+ PF HN
Sbjct: 218 LACDFSKKRPHASVGTHGYMAPEVLMKGQSYDSSADWFSFGCMLYKLLKGHSPFR--QHN 45
Query: 280 ETYRRIVKVDL 290
+ RI ++ +
Sbjct: 44 QGQARIDRMTM 12
>11780
Length = 1713
Score = 54.7 bits (130), Expect(2) = 1e-08, Method: Compositional matrix adjust.
Identities = 44/189 (23%), Positives = 80/189 (42%), Gaps = 5/189 (2%)
Frame = +3
Query: 76 DFEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLHHP 135
D EIG +GKG FG+VY + V K +K+ E +E + L H
Sbjct: 600 DLEIGEAIGKGDFGDVYKGMYRGQ------PVAIKQLKDKDRGEQSFLQEASVMTSLRHD 761
Query: 136 NILRLYNYFYDRRRIYLILEYAPRGELYKELQK--SCTFDEQRTATIMEELADALMYCHG 193
N++RL I+L+ E+ +G L + L+ ++ + A+ Y
Sbjct: 762 NLVRLIGVVLG-ETIFLVTEFMGKGNLVEYLRSRGRSVITKKDQINFATDTCAAMEYLES 938
Query: 194 KKVIHRDIKPXXXXXXXXXXXXIADFGWSVHAPSLRRKTMCGTLDYLPPEMI-EGRMHNE 252
K+++HRD+ ++DFG + + ++ + + PE + E ++H +
Sbjct: 939 KRLVHRDLAARNVLVHDDGKAKVSDFGLAKFG-DFSQTSVKFPIKWTAPEALRENKIH*Q 1115
Query: 253 --KVDLWCI 259
V+LW I
Sbjct: 1116VRHVELWHI 1142
Score = 21.9 bits (45), Expect(2) = 1e-08, Method: Compositional matrix adjust.
Identities = 20/88 (22%), Positives = 38/88 (43%), Gaps = 5/88 (5%)
Frame = +1
Query: 253 KVDLWCIGVLCYELL-VGNPPFESASHNETYRRIVKVDLKFPASVPMGAQDLISKLLRH- 310
K D+W G+L +E+ G P+ + ++ V+ + P G I +++
Sbjct: 1114 KSDMWSFGILLWEIYSFGRVPYPRIPLTDV---VMHVERGYRMEAPEGCPPEIYSIMKQA 1284
Query: 311 ---NPSERLPLAQVSAHPWVRANSRRVL 335
+P+ER V A R N++R +
Sbjct: 1285 WELDPNERPTFKSVLA----RLNNQRAV 1356
>13212
Length = 1067
Score = 56.6 bits (135), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 49/189 (25%), Positives = 83/189 (43%), Gaps = 10/189 (5%)
Frame = -1
Query: 150 IYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYCHGKKVIHRDIKPXXXXXX 209
++ +L + + +L+K T E + + E+ AL + H VIHRDIK
Sbjct: 1049 VFRVLWWGALDSIMVDLEKPMT--EAQICYVCHEMCMALDFLHRHHVIHRDIKAGNVLLT 876
Query: 210 XXXXXXIADFGWSVHAPSL--RRKTMCGTLDYLPPEMI-----EGRMHNEKVDLWCIGVL 262
+ADFG S +R T GT ++ PE++ + ++ K D+W +GV
Sbjct: 875 IDGEVKLADFGVSAKNTQTQQKRDTFIGTPYWMAPEVVLCETLKDTPYDFKADIWSLGVT 696
Query: 263 CYELLVGNPPFESASHNETYRRIVKVD---LKFPASVPMGAQDLISKLLRHNPSERLPLA 319
E PP + +I K D L+ P +D I+K L +P+ R A
Sbjct: 695 LIEFAQIEPPNKEMHPMRVLIKIHKSDPPTLEKPKKWTKLFKDFIAKCLVKDPNLRPTAA 516
Query: 320 QVSAHPWVR 328
++ HP+++
Sbjct: 515 ELLEHPFMK 489
>01966
Length = 1735
Score = 55.5 bits (132), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 36/137 (26%), Positives = 66/137 (48%), Gaps = 4/137 (2%)
Frame = -1
Query: 115 KEGVEHQLRREIEIQAHLHHPNILRLYNYFYDRRRIYLILEYAPRG-ELY-KELQKSCTF 172
++GV REI + L H NI+ L + + R++L+ E+ ++Y + +
Sbjct: 1594 EDGVPSSAIREIAMLRELRHTNIVCLEDVIMEDERLFLVFEFLSMDLKMYIDKFPEGVVL 1415
Query: 173 DEQRTATIMEELADALMYCHGKKVIHRDIKPXXXXXXXXXXXXIADFGWS-VHAPSLRRK 231
D + + + ++ + +CH ++++HRD+KP IADFG + A +R
Sbjct: 1414 DRRLVKSYVFQIVTGINFCHQRRIVHRDLKPQNLLINHTGAIKIADFGMARTFALPVRAY 1235
Query: 232 TM-CGTLDYLPPEMIEG 247
T TL Y PE++ G
Sbjct: 1234 THEVVTLWYRAPEILMG 1184
>07940
Length = 1336
Score = 55.5 bits (132), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 66/266 (24%), Positives = 103/266 (38%), Gaps = 73/266 (27%)
Frame = -3
Query: 79 IGRPLGKGKFGNVYLAR-----EKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHL- 132
+G LG+G FG V + + VA+K+L + ++E ++ L RE+E+ +
Sbjct: 830 LGDRLGEGAFGLVMKGEAMGIFKDNNSVTVAVKMLKEDATDREMMD--LIREMEMMKVIG 657
Query: 133 HHPNILRLYNYFYDRRRIYLILEYAPRGELYKELQK--------SCTFDEQR-------- 176
H NI+ L R +Y+I+E+AP G L L+ SC D ++
Sbjct: 656 KHKNIINLLGCCTQRGALYVIVEFAPHGNLRDFLKSHRPHGTSYSCIADYEQPVITSSSS 477
Query: 177 ----------------------TATI-------------MEELADALMYCH--------- 192
T+T+ M D + Y +
Sbjct: 476 SFSHPNSASSSAQGTSLGFIPGTSTVSFSTGSHRQDMLKMLTPKDLISYAYQVARGMEYL 297
Query: 193 -GKKVIHRDIKPXXXXXXXXXXXXIADFGWSVHAPSLR--RKTMCGTL--DYLPPEMIEG 247
K+ IHRD+ IADFG + + RKT G L ++ PE +
Sbjct: 296 ASKQCIHRDLAARNVLVAEEYVLKIADFGLTRNLQQFDYYRKTTDGRLPVKWMAPEALFD 117
Query: 248 RMHNEKVDLWCIGVLCYEL--LVGNP 271
R + K D+W GVL +E+ L GNP
Sbjct: 116 RKYTSKSDVWSYGVLLWEIFTLGGNP 39
>19094
Length = 898
Score = 54.7 bits (130), Expect = 6e-08, Method: Compositional matrix adjust.
Identities = 32/108 (29%), Positives = 52/108 (48%), Gaps = 2/108 (1%)
Frame = +1
Query: 171 TFDEQRTATIMEELADALMYCHGKKVIHRDIKPXXXXXXXXXXXXIADFGWSVHAPSL-- 228
T E+ ATI+ L Y H ++ IHRDIK +ADFG +
Sbjct: 46 TLVEREIATILYYTLKGL*YLHSRRKIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMA 225
Query: 229 RRKTMCGTLDYLPPEMIEGRMHNEKVDLWCIGVLCYELLVGNPPFESA 276
+R T+ GT ++ PE+I+ ++ D+W +G+ E+ GN E++
Sbjct: 226 KRNTVIGTPYWMAPEVIQEIGYDCVADIWSLGITALEMAEGNLHMETS 369
>17722
Length = 680
Score = 54.3 bits (129), Expect = 7e-08, Method: Compositional matrix adjust.
Identities = 29/95 (30%), Positives = 49/95 (51%), Gaps = 11/95 (11%)
Frame = -3
Query: 254 VDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPASVPMGAQDLISKLLRHNPS 313
VD W GV+ YE++ G PF + H+ + I+ ++KFP ++ A+ L+S LL NP
Sbjct: 678 VDWWGTGVVMYEMMCGRLPFYNRDHDVLFELILLQNVKFPRNLSEEAKTLLSGLLAKNPK 499
Query: 314 ERL-----PLAQVSAHP------WVRANSRRVLPP 337
RL + ++ HP W ++++ PP
Sbjct: 498 RRLGGSEADVTEIKTHPFFQCINWDDLAAKKITPP 394
>26711
Length = 405
Score = 53.1 bits (126), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 31/116 (26%), Positives = 54/116 (46%), Gaps = 3/116 (2%)
Frame = -2
Query: 180 IMEELADALMYCHGKKVIHRDIKPXXXXXXXXXXXXIA--DFGWSVHA-PSLRRKTMCGT 236
+++++ D L + H + V+H D+KP + DFG + P GT
Sbjct: 401 VVKQVLDILQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARKLYPPQETFLNHGT 222
Query: 237 LDYLPPEMIEGRMHNEKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKF 292
+ PE ++ + + D+W +GVL Y LL G PF++ S E+ ++ D F
Sbjct: 221 PGFTSPEALDVKPISTASDVWGVGVLAYILLSGQSPFQADSATESLKKTQTCDWSF 54
>29581
Length = 1278
Score = 53.1 bits (126), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 40/146 (27%), Positives = 63/146 (43%), Gaps = 5/146 (3%)
Frame = -2
Query: 131 HLHHPNILRLYNYFYDRR--RIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADAL 188
+L H NI++L + ++L++EY + F E + I+ +L L
Sbjct: 1187 NLRHQNIVQLQEVVVGKSLDSLFLVMEYCEQDLASLLDNMPAPFSESQVKCIVLQLLKGL 1008
Query: 189 MYCHGKKVIHRDIKPXXXXXXXXXXXXIADFGWSVH--APSLRRKTMCGTLDYLPPEMIE 246
Y H +IHRD+K IADFG + + P TL Y PE++
Sbjct: 1007 RYLHEAFIIHRDLKVSNLLMTDKGCVKIADFGLARNYGKPQKPMTPKVVTLWYRAPELLF 828
Query: 247 G-RMHNEKVDLWCIGVLCYELLVGNP 271
G + H+ +D+W G + ELL P
Sbjct: 827 GSKTHSTAIDMWSAGCILGELLGHKP 750
>19301
Length = 712
Score = 52.4 bits (124), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 36/140 (25%), Positives = 56/140 (40%)
Frame = +2
Query: 83 LGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLHHPNILRLYN 142
LG G G V+L + L ++ + V +I L+HPNI+
Sbjct: 329 LGSGAQGAVFLGK------------LCAEEVAVKKVRDIKETDIRNLRKLNHPNIISFKG 472
Query: 143 YFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYCHGKKVIHRDIK 202
+I+EY P G+LY+ L+ +++A + Y H K+IHRD+K
Sbjct: 473 VCTQAPCYCIIMEYCPYGQLYEVLRDGKEIPPALVLDWSKQIASGMNYLHSHKIIHRDLK 652
Query: 203 PXXXXXXXXXXXXIADFGWS 222
I+DFG S
Sbjct: 653 SPNVLVAKNDVVKISDFGTS 712
>04852
Length = 1462
Score = 51.6 bits (122), Expect = 5e-07, Method: Compositional matrix adjust.
Identities = 52/257 (20%), Positives = 106/257 (41%), Gaps = 35/257 (13%)
Frame = +1
Query: 103 VALKVL--FKSQIEKEGVEHQLRREIEIQAHLHHPNILRLYNYFYDRRRIYLILEYAPRG 160
VA+K+L + +E++ +L+ ++ H NI+ +++I+E+A G
Sbjct: 28 VAVKMLRDIVTAVEEQDFVQELQVMKAVKKMGSHINIVNFLGCCTQGGPLWVIVEFAKNG 207
Query: 161 ELYKELQKSC--------------------------TFDEQRTATIMEELADALMYCHGK 194
L ++ +SC + + ++A + + +
Sbjct: 208 NL-RDFLESCRDGINGYGKFVSPQDPGWYTKTPGGHVIRRKNLLSYAFQIARGMEFLASR 384
Query: 195 KVIHRDIKPXXXXXXXXXXXXIADFGWSVHAPSLRRKTMCGTL--DYLPPEMIEGRMHNE 252
K IHRD+ IADFG S ++++ G L ++ PE + +
Sbjct: 385 KCIHRDLAARNVLVTEEHVLKIADFGLSRTGDYYKKRS-GGRLPVKWMAPEALFDMRYTT 561
Query: 253 KVDLWCIGVLCYELL-VGNPPFESASHNETYRRIVKVDLKFP----ASVPMGAQDLISKL 307
K D+W GV+ +E+ +G P+ S + E Y +++ + P AS + A ++ +
Sbjct: 562 KSDVWSFGVVLWEIFSLGGMPYASIPNEELYSKLLDDAYRMPRPELASGNLYA--IMERC 735
Query: 308 LRHNPSERLPLAQVSAH 324
+ PS+R +Q+ H
Sbjct: 736 WLNRPSDRPEFSQLVGH 786
>38560
Length = 479
Score = 51.2 bits (121), Expect = 5e-07, Method: Compositional matrix adjust.
Identities = 28/97 (28%), Positives = 49/97 (50%), Gaps = 1/97 (1%)
Frame = -3
Query: 232 TMCGTLDYLPPEMIEGRMH-NEKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDL 290
T CG+ Y PE+I G + + D+W +GVL Y LL G PF+ + ++ K
Sbjct: 408 TCCGSPAYAAPELISGLEYLGSEADIWSMGVLLYALLCGYLPFDDEKXSHL*QKNQKRKD 229
Query: 291 KFPASVPMGAQDLISKLLRHNPSERLPLAQVSAHPWV 327
+ P + L+ +L+ +PS R+ + ++ H W+
Sbjct: 228 EVPEWLSEDTTKLLEGMLQTDPSHRITIRRLLDHHWL 118
>27405
Length = 532
Score = 51.2 bits (121), Expect = 6e-07, Method: Compositional matrix adjust.
Identities = 42/175 (24%), Positives = 76/175 (43%), Gaps = 5/175 (2%)
Frame = -3
Query: 88 FGNVYLAREKKSHFIVALKVLFKSQIEKEGVEH-QLRREIE---IQAHLHHPNILRLYNY 143
FG VY R+ + + A+K L K +I+ +G E L I + P I+ +
Sbjct: 527 FGEVYGCRKADTGKMYAMKCLDKKRIKMKGGETLALNERIMLSLVSTGEGSPFIVCMTYA 348
Query: 144 FYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYCHGKKVIHRDIKP 203
F ++ IL+ G+L+ L + F E+ E+ L + H + V++RD+KP
Sbjct: 347 FQTPEKLCFILDLMNGGDLHYHLSQHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKP 168
Query: 204 XXXXXXXXXXXXIADFGWSVHAPSLRRKTMCGTLDYLPPE-MIEGRMHNEKVDLW 257
I+D G + + GT Y+ PE +++G+ ++ D +
Sbjct: 167 ANILLDENGHVRISDLGLACDFSKKKPHASVGTHGYMAPEVLMKGQAYDSSADWF 3
>14477
Length = 493
Score = 50.8 bits (120), Expect = 8e-07, Method: Compositional matrix adjust.
Identities = 40/142 (28%), Positives = 65/142 (45%), Gaps = 2/142 (1%)
Frame = -1
Query: 83 LGKGKFGNVY--LAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLHHPNILRL 140
LG G FG+V + R VA+KVL + ++ V+ +L +E E+ + H +I+RL
Sbjct: 466 LGAGNFGSVMKGVCRLDDREIPVAIKVLKNADLDP-SVQSELIKEAEVMKKMDHMHIVRL 290
Query: 141 YNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYCHGKKVIHRD 200
+ + L+LE A G L K L K+ +M +++ + Y K +HRD
Sbjct: 289 IG-LCEGETMMLVLELAKLGPLNKFLPKNKHLPLWNILELMWQVSQGMEYLEANKFVHRD 113
Query: 201 IKPXXXXXXXXXXXXIADFGWS 222
+ I+DFG S
Sbjct: 112 LAARNILLCDEHFAKISDFGMS 47
>27274
Length = 396
Score = 50.1 bits (118), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 26/96 (27%), Positives = 50/96 (52%), Gaps = 11/96 (11%)
Frame = -1
Query: 243 EMIEGRMHNEKVDLWCIGVLCYELLVGNPPFE--------SASHNETYRRIVKV---DLK 291
E++ G+ H VD+W +G+L +ELL G+ PFE + + Y +I++ D+
Sbjct: 375 ELLRGQQHGPTVDMWSLGILLHELLSGHVPFEPERGSRQMARNMMAVYAQIIRGSSRDVC 196
Query: 292 FPASVPMGAQDLISKLLRHNPSERLPLAQVSAHPWV 327
++ D + +L++ ++RL Q +HPW+
Sbjct: 195 DGLALSTHGADFLRRLVQLEDTKRLTSQQAFSHPWI 88
>20559
Length = 430
Score = 47.4 bits (111), Expect(2) = 3e-06, Method: Compositional matrix adjust.
Identities = 26/78 (33%), Positives = 46/78 (58%)
Frame = -2
Query: 77 FEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLHHPN 136
+E +G+G +G V+ A+ +++H IVALK + + + EGV REI + L H N
Sbjct: 369 YEKLEKIGEGTYGTVFKAKNRETHEIVALKRV-RLDDDDEGVPSSALREICLLKELKHRN 193
Query: 137 ILRLYNYFYDRRRIYLIL 154
I+RL++ + R++ L+
Sbjct: 192 IVRLHDVLHSERKLTLVF 139
Score = 21.2 bits (43), Expect(2) = 3e-06, Method: Compositional matrix adjust.
Identities = 6/12 (50%), Positives = 9/12 (75%)
Frame = -1
Query: 188 LMYCHGKKVIHR 199
L++CH V+HR
Sbjct: 37 LVFCHSNNVLHR 2
>21808
Length = 1011
Score = 48.9 bits (115), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 45/197 (22%), Positives = 73/197 (37%), Gaps = 6/197 (3%)
Frame = +1
Query: 125 EIEIQAHLHHPNILRLYNYFYDRRRIYLILEYAPRGELYKELQ-KSCTFDEQRTATIMEE 183
E +I L HP +++LY I++I E G L + LQ K I +
Sbjct: 82 EAQIMKKLRHPKLIQLYAVCTQDDPIFIITELMKNGSLLEFLQGKGRVLKLPALIDIGAQ 261
Query: 184 LADALMYCHGKKVIHRDIKPXXXXXXXXXXXXIADFGWSVHAPSLRRKTMCGT---LDYL 240
+A + Y + IHRD+ IADFG + + G + +
Sbjct: 262 IACGMAYLESQNYIHRDLAARNILVSDNNTVKIADFGLARVIKEDEYEARVGARFPIKWT 441
Query: 241 PPEMIEGRMHNEKVDLWCIGVLCYELLV-GNPPFESASHNETYRRIV-KVDLKFPASVPM 298
PE K D+W G+L E + G P+ ++ E ++ + P P
Sbjct: 442 APEAANYNRFTIKSDVWSFGILLTETVTYGRVPYPGMTNAEVLHQVEHGYRMPCPPGCPK 621
Query: 299 GAQDLISKLLRHNPSER 315
D++ + R ER
Sbjct: 622 PLYDIMLECWRKEEMER 672
>19761
Length = 473
Score = 48.1 bits (113), Expect = 5e-06, Method: Compositional matrix adjust.
Identities = 26/97 (26%), Positives = 48/97 (49%), Gaps = 4/97 (4%)
Frame = -3
Query: 174 EQRTATIMEELADAL--MYCHGKKVIHRDIKPXXXXXXXXXXXXIADFGWS--VHAPSLR 229
E+ + + A AL M+ H ++HRD+KP + D G + + P+
Sbjct: 426 ERLIVCWLMQTASALNYMHTHTPVILHRDLKPQNIYVTEKGDVRLGDLGLARKLTGPADF 247
Query: 230 RKTMCGTLDYLPPEMIEGRMHNEKVDLWCIGVLCYEL 266
+ GT+ YL PE++ + +N K D+W +G + Y++
Sbjct: 246 ATSQVGTIMYLSPEILSQQPYNSKSDIWSLGCVFYDI 136
>04138
Length = 800
Score = 46.2 bits (108), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 31/107 (28%), Positives = 48/107 (44%), Gaps = 6/107 (5%)
Frame = +1
Query: 188 LMYCHGKKVIHRDIKPXXXXXXXXXXXXIADFG----WSVHAPSLRRKT-MCGTLDYLPP 242
L Y H K++HRD+K +ADFG +SV+ R T TL Y PP
Sbjct: 52 LYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRPP 231
Query: 243 EMIEG-RMHNEKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKV 288
E++ G R ++ +D W G + E+ NP + + I ++
Sbjct: 232 ELLLGDRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQNQLTLITQL 372
>28157
Length = 400
Score = 45.4 bits (106), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 37/119 (31%), Positives = 54/119 (45%), Gaps = 7/119 (5%)
Frame = +3
Query: 112 QIEKEGVEHQLRREIEIQAHLHHPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCT 171
+IE E + +E++ + + HPNI+ LY D + L++EYA G LY L S
Sbjct: 21 RIESEQEKKSFMQELKQLSRVSHPNIVCLYGACRDHP-VCLVMEYAEGGSLYNVLHGSGP 197
Query: 172 FDEQRTATIME---ELADALMYCHG---KKVIHRDIK-PXXXXXXXXXXXXIADFGWSV 223
+ A M + A + Y HG K +IHRD+K P I DFG +
Sbjct: 198 QPQYTAAHAMNWLLQCALGVEYLHGMKPKALIHRDLKPPNLLLIQCGTKLKICDFGTAC 374
>12672
Length = 773
Score = 45.4 bits (106), Expect = 4e-05, Method: Compositional matrix adjust.
Identities = 29/96 (30%), Positives = 43/96 (44%), Gaps = 6/96 (6%)
Frame = +3
Query: 180 IMEELADALMYCHGKKVIHRDIKPXXXXXXXXXXXXIADFGWSVHAPSLRRKT------M 233
I++ A + Y + +HRDIK + DF V APS KT +
Sbjct: 6 IVKGTASGIQYLNDNGHVHRDIKTANILLDSEYTAKVGDFATVVSAPSGEGKTVQNASVV 185
Query: 234 CGTLDYLPPEMIEGRMHNEKVDLWCIGVLCYELLVG 269
GT YL PE I + + K+D + GV+ E++ G
Sbjct: 186 IGTAAYLAPEAIHFDV-STKLDSYSFGVVLLEVITG 290
>37602
Length = 804
Score = 36.6 bits (83), Expect(2) = 6e-05, Method: Compositional matrix adjust.
Identities = 28/104 (26%), Positives = 45/104 (43%), Gaps = 6/104 (5%)
Frame = -1
Query: 136 NILRLYNYF--YDRR-RIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYCH 192
NI YF Y RR ++++ +EY G + + E + A + E L Y H
Sbjct: 345 NIQTFVGYFDSYLRREKLWIAMEYCGGGSMQDIYHVTGPLTEPQIAFVCRETLKGLHYLH 166
Query: 193 GKKVIHRDIKPXXXXXXXXXXXXIADFGWSV---HAPSLRRKTM 233
+ +HRDIK +ADF W V H+ ++++K
Sbjct: 165 RRGKMHRDIKGANILLTEEGDVKLADF-WRVSSNHSHNVQKKVF 37
Score = 27.3 bits (59), Expect(2) = 6e-05, Method: Compositional matrix adjust.
Identities = 11/28 (39%), Positives = 19/28 (67%)
Frame = -2
Query: 68 LTRHFTIDDFEIGRPLGKGKFGNVYLAR 95
+ R +DDFE+ + +G G +G+VY A+
Sbjct: 530 IQRRNPLDDFELIQRVGSGTYGDVYKAK 447
>00715
Length = 1788
Score = 43.9 bits (102), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 32/162 (19%), Positives = 59/162 (36%), Gaps = 24/162 (14%)
Frame = +1
Query: 172 FDEQRTATIMEELADALMYCHGKKVIHRDIKPXXXXXXXXXXXXIADFGWS--------- 222
D ++ ++A L Y H ++H D+KP IADFG
Sbjct: 229 IDSSMRLSLALQMARGLHYLHSINIVHLDLKPANCLLTRDLKLRIADFGCCHQLTPTGLD 408
Query: 223 ---------------VHAPSLRRKTMCGTLDYLPPEMIEGRMHNEKVDLWCIGVLCYELL 267
+ + GTL Y PE+++G + + D++ +G+ +++
Sbjct: 409 MGEREGGMAGNELELTPVQGAWKNELAGTLAYRAPELLKGLQPSVRSDVYSLGITLWQMC 588
Query: 268 VGNPPFESASHNETYRRIVKVDLKFPASVPMGAQDLISKLLR 309
P+E + ++V DL+ P P D + R
Sbjct: 589 TRQGPYEGVPAHAVVYQVVSKDLR-PCPPPSTEDDPFEVMFR 711
>32957
Length = 645
Score = 42.7 bits (99), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 20/60 (33%), Positives = 33/60 (55%)
Frame = +3
Query: 219 FGWSVHAPSLRRKTMCGTLDYLPPEMIEGRMHNEKVDLWCIGVLCYELLVGNPPFESASH 278
F V R +T CGT +Y+ PE+ E + + ++VD W +G+L +ELL S+ +
Sbjct: 3 FALCVEKSGGRTRTFCGTREYMAPEVHERKEYGKEVDWWGLGILLHELLAAQIKKHSSCY 182
>03508
Length = 1463
Score = 41.6 bits (96), Expect = 5e-04, Method: Compositional matrix adjust.
Identities = 28/124 (22%), Positives = 58/124 (46%), Gaps = 3/124 (2%)
Frame = +1
Query: 152 LILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYCHGKKVIHRDIKP-XXXXXXX 210
LI E+ + +K+L + TF + + EL AL +CH ++HRD+KP
Sbjct: 811 LIFEHVNNTD-FKQLYQ--TFTDYDIRFYLYELMKALDFCHSMGIMHRDVKPHNVMIDHE 981
Query: 211 XXXXXIADFGWS-VHAPSLRRKTMCGTLDYLPPE-MIEGRMHNEKVDLWCIGVLCYELLV 268
+ D+G + + P + + + PE +++ +M++ +D+W +G + ++
Sbjct: 982 NKKLRLIDWGLAEFYHPGMEYNVRVASRYFKGPELLLDYQMYDYSLDMWSLGCMFASMIF 1161
Query: 269 GNPP 272
P
Sbjct: 1162RKEP 1173
>32359
Length = 928
Score = 41.6 bits (96), Expect = 5e-04, Method: Compositional matrix adjust.
Identities = 27/85 (31%), Positives = 43/85 (50%), Gaps = 6/85 (7%)
Frame = -1
Query: 80 GRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLHHPNILR 139
+ +G G FG VY A+ + +VA+K + + + K RE++I L H NI++
Sbjct: 415 AKVIGNGSFGVVYQAKLVDTSELVAIKKVLQDKRFKN-------RELQIMRKLEHQNIVK 257
Query: 140 LYNYFY------DRRRIYLILEYAP 158
L +FY D + L+LEY P
Sbjct: 256 LKFFFYSSGEKKDEVFLNLVLEYVP 182
>07833
Length = 1504
Score = 39.7 bits (91), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 38/187 (20%), Positives = 75/187 (40%), Gaps = 9/187 (4%)
Frame = -3
Query: 132 LHHPNILRLYNYFYDRRRIYLILEYAPRGELYKEL--QKSCTFDEQRTATIMEELADALM 189
+HPN+L + + LI ++ P G LY L + D+ ++ ++A +
Sbjct: 1448 FNHPNVLPVLACCNQPPNLVLISQFMPFGSLYNTLHGESGIVVDQNQSLRFAMDIARGME 1269
Query: 190 YCHGKKVIHRDI----KPXXXXXXXXXXXXIADFGWSVHAPSLRRKTMCGTLDYLPPEMI 245
+ H + + K +AD+ +S H K + ++ PE +
Sbjct: 1268 FLHSMEPTIPNFLLTSKHVMIDEDLTARINMADYCFSFH-----EKGKVYSPAWMAPEAL 1104
Query: 246 EGR---MHNEKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPASVPMGAQD 302
+ R ++ D+W +L +EL PF S E ++ L+ S+P G
Sbjct: 1103 QRRPDDINTRAADMWSFAILMWELETREVPFAELSSMEVGMKVALEGLRI--SIPPGISL 930
Query: 303 LISKLLR 309
+S+L++
Sbjct: 929 HMSRLIK 909
>11185
Length = 473
Score = 38.9 bits (89), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 23/111 (20%), Positives = 42/111 (37%), Gaps = 24/111 (21%)
Frame = +1
Query: 184 LADALMYCHGKKVIHRDIKPXXXXXXXXXXXXIADFG----------------------W 221
L L Y H ++ D++P ADFG W
Sbjct: 28 LVTGLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQW 207
Query: 222 SVHAPS--LRRKTMCGTLDYLPPEMIEGRMHNEKVDLWCIGVLCYELLVGN 270
++ + +++ G+ Y+ PE+ +G + DLW +G + YE+ G+
Sbjct: 208 NIQSAEEMMKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSGS 360
>03106
Length = 2384
Score = 38.9 bits (89), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 24/80 (30%), Positives = 39/80 (48%), Gaps = 1/80 (1%)
Frame = +2
Query: 245 IEGRMHNEKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDL-KFPASVPMGAQDL 303
+E + K D+W G + YE+ + PF S + Y + DL P P G L
Sbjct: 2 LESVLDYSKADVWAAGAVAYEIFGASNPFYSRLDSACYS---QHDLPSLPGDTPEGVVRL 172
Query: 304 ISKLLRHNPSERLPLAQVSA 323
++ +L +P++R P A V+A
Sbjct: 173 VTSMLERDPAQR-PSAVVAA 229
>07291
Length = 833
Score = 38.5 bits (88), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 31/147 (21%), Positives = 63/147 (42%), Gaps = 7/147 (4%)
Frame = +1
Query: 183 ELADALMYCHGKKVIHRDIKPXXXXXXXXXXXXIADFG--WSVHAPSLRRKTMCGTLD-- 238
++AD + Y KV+HR++ ++D+G S+ S D
Sbjct: 73 QIADGMAYLQEVKVVHRNLAARNCIVTEDGRLQLSDYGVTGSLFPQSYYTADDSPARDLV 252
Query: 239 -YLPPEMIEGRMHNEKVDLWCIGVLCYELLV-GNPPFESASHNETYRRIVKVD-LKFPAS 295
++ PE I+ + K D+W GV+ +ELL G P+ ++ + + +K P
Sbjct: 253 KWMAPETIDNFHFSSKSDVWAFGVVLWELLTRGITPYPDVENSSLLPYLKEGHRMKKPKQ 432
Query: 296 VPMGAQDLISKLLRHNPSERLPLAQVS 322
P ++++ +P +R A+++
Sbjct: 433 SPEPVYEMMTACWNESPEQRPDFAELN 513
>29590
Length = 320
Score = 38.5 bits (88), Expect = 0.004, Method: Composition-based stats.
Identities = 19/57 (33%), Positives = 31/57 (54%), Gaps = 3/57 (5%)
Frame = +3
Query: 231 KTMCGTLDYLPPEMIEGRMHNEKVDLWCIGVLCYELLVGNPPF---ESASHNETYRR 284
+ + GT DY+ PE+++ + + D+W +GVL Y +L PF S H+ T R
Sbjct: 48 RDIIGTPDYVAPEVLDYEPLSIQTDMWSLGVLSYVMLTACSPFVGITSKKHSATSLR 218
>12786
Length = 460
Score = 37.7 bits (86), Expect = 0.008, Method: Compositional matrix adjust.
Identities = 31/121 (25%), Positives = 47/121 (38%), Gaps = 24/121 (19%)
Frame = -3
Query: 183 ELADALMYCHGKKVIHRDIKPXXXXXXXXXXXXIADFGWS----VHAPSLRRKTMCGTLD 238
E+ A+ H + VIH D+KP I DFG + S+ + + GT
Sbjct: 386 EMLRAVKALHNEGVIHSDLKPANFMLVAGNLKLI-DFGIANTLQQDKTSVLKDSRVGTPS 210
Query: 239 YLPPEMI------------EGRMHNEK--------VDLWCIGVLCYELLVGNPPFESASH 278
Y+ PE I E H K D+W +G + Y ++ G PF+ +
Sbjct: 209 YMSPEAIMAACDDSADDSMEEDGHRTKPKYKVGVRSDVWSLGCILYNMVYGRTPFQHIKN 30
Query: 279 N 279
N
Sbjct: 29 N 27
>02638
Length = 1490
Score = 36.2 bits (82), Expect = 0.017, Method: Compositional matrix adjust.
Identities = 21/96 (21%), Positives = 41/96 (42%), Gaps = 5/96 (5%)
Frame = +1
Query: 235 GTLDYLPPEMIEGRMHNEKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLK--- 291
GT+ ++ PE++ G + D+W +G + E+ PP+ S + I K+
Sbjct: 22 GTIAFMAPEVLRGESYGRACDVWSVGCVMIEMCTCRPPWNSHDISNHLALIFKIASSVDP 201
Query: 292 --FPASVPMGAQDLISKLLRHNPSERLPLAQVSAHP 325
P ++ +DL+ + L + R + HP
Sbjct: 202 PPIPENMSPPVRDLMLRCLEQDSDFRPSAKDLLMHP 309
>31489
Length = 329
Score = 34.3 bits (77), Expect = 0.070, Method: Composition-based stats.
Identities = 20/84 (23%), Positives = 40/84 (47%), Gaps = 6/84 (7%)
Frame = +3
Query: 126 IEIQAHLHHPNI------LRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTAT 179
I+I H H NI L+ + ++D + I+++ + +L++ + E+
Sbjct: 3 IKILKHFKHDNIISIREILKPKDSYHDFKDIHVVFDLM-ESDLHRIIYSDQPLTEEHIRY 179
Query: 180 IMEELADALMYCHGKKVIHRDIKP 203
+ ++ L Y H V+HRD+KP
Sbjct: 180 FLYQILRGLKYIHSANVVHRDLKP 251
>00638
Length = 1595
Score = 33.9 bits (76), Expect = 0.098, Method: Compositional matrix adjust.
Identities = 18/52 (34%), Positives = 29/52 (55%)
Frame = +2
Query: 152 LILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYCHGKKVIHRDIKP 203
LI E+ + +K+L + TF + + EL AL +CH ++HRD+KP
Sbjct: 356 LIFEHVNNTD-FKQLYQ--TFTDYDIRFYLYELMKALDFCHSMGIMHRDVKP 502
>28638
Length = 1458
Score = 33.5 bits (75), Expect = 0.13, Method: Compositional matrix adjust.
Identities = 25/96 (26%), Positives = 41/96 (42%), Gaps = 4/96 (4%)
Frame = -1
Query: 182 EELADALMYCHG--KKVIHRDIKPXXXXXX--XXXXXXIADFGWSVHAPSLRRKTMCGTL 237
++L AL++ +IH D+KP I DFG S R +
Sbjct: 816 QQLCTALLFLATPEMNIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQ-RIYQYIQSR 640
Query: 238 DYLPPEMIEGRMHNEKVDLWCIGVLCYELLVGNPPF 273
Y PE++ G ++ +D+W +G + E+ G PP
Sbjct: 639 FYRSPEVLLGVPYDLAIDMWSLGCILVEMHTGEPPL 532
>20655
Length = 1181
Score = 33.5 bits (75), Expect = 0.14, Method: Compositional matrix adjust.
Identities = 22/64 (34%), Positives = 34/64 (53%), Gaps = 4/64 (6%)
Frame = +2
Query: 283 RRIVKVDLKFP----ASVPMGAQDLISKLLRHNPSERLPLAQVSAHPWVRANSRRVLPPS 338
+RI +FP + V A+DLI +L +P +RL + QV A WV N+ ++P +
Sbjct: 8 KRIRNGQYEFPKPEWSRVSQDAKDLIRGMLCTDPDKRLNIKQVMASKWVADNT--MVPQT 181
Query: 339 ALQS 342
L S
Sbjct: 182 PLMS 193
>36002
Length = 253
Score = 32.3 bits (72), Expect = 0.27, Method: Compositional matrix adjust.
Identities = 18/50 (36%), Positives = 25/50 (50%), Gaps = 4/50 (8%)
Frame = +1
Query: 282 YRRIVKVDLKFPA----SVPMGAQDLISKLLRHNPSERLPLAQVSAHPWV 327
+ RI + FP+ ++ A+DLI LL P +R A V HPWV
Sbjct: 61 FNRIQDGNYFFPSMEWSAISSSAKDLIRHLLVREPRKRYSAADVLKHPWV 210
>31120
Length = 439
Score = 31.6 bits (70), Expect = 0.47, Method: Compositional matrix adjust.
Identities = 26/98 (26%), Positives = 49/98 (50%), Gaps = 11/98 (11%)
Frame = +1
Query: 243 EMIEGRMHNEKV-DLWCIGVLCYELLVGNPPFESASHNE----------TYRRIVKVDLK 291
E++ G ++ K+ D W +GV+ + +L G PF+ ++ N+ ++RR ++ DL
Sbjct: 1 EVVCGVPYDPKMADAWSLGVILFIMLNGKMPFDDSNLNKLLEDQRSKKYSFRRKLQ-DLV 177
Query: 292 FPASVPMGAQDLISKLLRHNPSERLPLAQVSAHPWVRA 329
P A+ +S LL N + R L +V W++
Sbjct: 178 SP-----NARSTVSVLLEPNSAMRWDLNEVLNCQWLQT 276
>18401
Length = 463
Score = 31.2 bits (69), Expect = 0.69, Method: Compositional matrix adjust.
Identities = 14/49 (28%), Positives = 24/49 (48%)
Frame = -3
Query: 232 TMCGTLDYLPPEMIEGRMHNEKVDLWCIGVLCYELLVGNPPFESASHNE 280
T+ T Y PE+I + D+W +G + +EL G F++ + E
Sbjct: 455 TIVSTRHYRAPEVILELGWSHPCDVWSVGCIMFELYTGYTLFQTHDNKE 309
>33586
Length = 551
Score = 30.0 bits (66), Expect = 1.3, Method: Compositional matrix adjust.
Identities = 16/48 (33%), Positives = 25/48 (52%)
Frame = +2
Query: 137 ILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEEL 184
I+ L+ F ++YLILE+ G+L+ L K F E+ + EL
Sbjct: 407 IVHLHYAFQTEGKLYLILEFLRGGDLFTRLSKEVMFTEEDVKFYLAEL 550
>16708
Length = 1397
Score = 30.0 bits (66), Expect = 1.4, Method: Compositional matrix adjust.
Identities = 33/145 (22%), Positives = 52/145 (35%), Gaps = 7/145 (4%)
Frame = -1
Query: 83 LGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLHHPNILRLYN 142
LGKG FG VY AR +H ALK + VE R I+ + + +
Sbjct: 1379 LGKGVFGKVYEARLLSTHEKAALKTSILCHHSLDEVEALGR----IEGGFYLAQMFGAWV 1212
Query: 143 YFYDRRRIYLILEYAPRGEL------YKELQKSCTFDE-QRTATIMEELADALMYCHGKK 195
++ ++L + G L YK + + I + AL + H
Sbjct: 1211 TCLPFPKMNILLHFYEMGPLCNVYAHYKNKEMPIRWSNPAMVCCIAGQXVCALEHIHELG 1032
Query: 196 VIHRDIKPXXXXXXXXXXXXIADFG 220
V+H D+K + D+G
Sbjct: 1031 VVHMDVKADNVLVDAHGNCKLTDYG 957
>18481
Length = 437
Score = 29.6 bits (65), Expect = 1.7, Method: Compositional matrix adjust.
Identities = 33/118 (27%), Positives = 52/118 (44%), Gaps = 7/118 (5%)
Frame = -1
Query: 112 QIEKEGVEHQL-RREIEIQAHL-HHPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKS 169
+IE V+HQL E ++ + HP + +Y+Y ++ L++E G +EL
Sbjct: 392 KIEAIDVKHQLLHYEAKVYEQIGRHPGLPTMYHYGTEKHFNALVMELL--GPSLEELFVI 219
Query: 170 CT--FDEQRTATIMEELADALMYCHGKKVIHRDIKPXXXXXXXX---XXXXIADFGWS 222
C F + + ++L L + H K IHRD+KP I DFG S
Sbjct: 218 CKRRFTLKTILMVSDQLLSRLEFIHQKCFIHRDLKPDNFLMGLGRHCHRLYIIDFGLS 45
>21418
Length = 831
Score = 28.9 bits (63), Expect = 2.9, Method: Compositional matrix adjust.
Identities = 16/49 (32%), Positives = 25/49 (51%), Gaps = 4/49 (8%)
Frame = +2
Query: 283 RRIVKVDLKFP----ASVPMGAQDLISKLLRHNPSERLPLAQVSAHPWV 327
+RI FP +V A+DLI +L +PS+RL + V + W+
Sbjct: 8 KRIRSGQYDFPDPEWTNVSQAAKDLIKGMLNVDPSKRLCIEDVLRNKWI 154
>00409
Length = 1260
Score = 28.9 bits (63), Expect = 3.2, Method: Compositional matrix adjust.
Identities = 16/29 (55%), Positives = 20/29 (68%)
Frame = -1
Query: 17 APSGLSTLPQRVLRKEPVTPSALVLMSRS 45
APSGLST+ Q RKE + S+ V MS+S
Sbjct: 768 APSGLSTMMQSKPRKEKWSXSSTVHMSKS 682
>14104
Length = 573
Score = 27.7 bits (60), Expect = 7.7, Method: Compositional matrix adjust.
Identities = 15/51 (29%), Positives = 26/51 (50%)
Frame = +1
Query: 284 RIVKVDLKFPASVPMGAQDLISKLLRHNPSERLPLAQVSAHPWVRANSRRV 334
R+ ++ KF + P A + L+ +P+ERL Q+ HP++ N V
Sbjct: 55 RLEPLEEKFSNAAP-QAMSFMQSCLKMDPAERLTCHQLLQHPYMDLNMEMV 204
>20513
Length = 405
Score = 27.3 bits (59), Expect = 9.8, Method: Compositional matrix adjust.
Identities = 9/30 (30%), Positives = 18/30 (60%)
Frame = -1
Query: 302 DLISKLLRHNPSERLPLAQVSAHPWVRANS 331
D ++ +L +P +R AQ HPW++ ++
Sbjct: 282 DFLAPMLEFDPEQRATAAQSLQHPWLKLDA 193
>16350
Length = 1108
Score = 27.3 bits (59), Expect = 9.8, Method: Compositional matrix adjust.
Identities = 9/30 (30%), Positives = 18/30 (60%)
Frame = +3
Query: 302 DLISKLLRHNPSERLPLAQVSAHPWVRANS 331
D ++ +L +P +R AQ HPW++ ++
Sbjct: 762 DFLAPMLEFDPEQRATAAQSLQHPWLKLDA 851
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000370229 | hsapiens_gene_ensembl |
G2/mitotic-specific cyclin-B1. [Source:Uniprot/SWISSPROT;Acc:P14635]
(396 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
25961 179 5e-59
11451 159 3e-39
16444 124 9e-29
19735 37 0.019
31532 35 0.066
>25961
Length = 538
Score = 179 bits (454), Expect(2) = 5e-59, Method: Compositional matrix adjust.
Identities = 78/139 (56%), Positives = 101/139 (72%)
Frame = -1
Query: 163 DPNLCSEYVKDIYAYLRQLEEEQAVRPKYLLGREVTGNMRAILIDWLVQVQMKFRLLQET 222
+P L SEYV DIY Y+RQ+E+ VR YL G ++TG MR IL+DWL QV +F LLQET
Sbjct: 532 NPQLVSEYVNDIYDYMRQMEQRLCVRASYLEGTDITGKMRCILVDWLCQVHHRFHLLQET 353
Query: 223 MYMTVSIIDRFMQNNCVPKKMLQLVGVTAMFIASKYEEMYPPEIGDFAFVTDNTYTKHQI 282
+Y+TVSI+DRF+Q V + LQLVGVT+M +ASKYEE++ PE+ DF +++DN Y K I
Sbjct: 352 LYLTVSIMDRFLQQKPVTRNKLQLVGVTSMLVASKYEELFAPEVADFVYISDNAYAKADI 173
Query: 283 RQMEMKILRALNFGLGRPL 301
+ME ILR LNF G+P
Sbjct: 172 HEMERDILRTLNFSFGKPF 116
Score = 67.0 bits (162), Expect(2) = 5e-59, Method: Compositional matrix adjust.
Identities = 30/43 (69%), Positives = 36/43 (83%)
Frame = -2
Query: 297 LGRPLPLHFLRRASKIGEVDVEQHTLAKYLMELTMLDYDMVHF 339
LG L LHFLRR SK G+VD +HTLAKYLMELT+++YDMVH+
Sbjct: 129 LGNLLCLHFLRRNSKAGQVDAVKHTLAKYLMELTVIEYDMVHY 1
>11451
Length = 1321
Score = 159 bits (401), Expect = 3e-39, Method: Compositional matrix adjust.
Identities = 92/259 (35%), Positives = 149/259 (57%), Gaps = 5/259 (1%)
Frame = +2
Query: 124 TASPSPMETSGCAPAEEDLCQAFSDVILAVNDVDAEDGADPNLCSE---YVKDIYAYLRQ 180
T S ++ SG EE + +V + +V+ E + E Y +DIY+YL
Sbjct: 359 TEDSSYLDMSGVEDEEE----SEDNVSMGSEEVEEEPQDSATIIEEVPEYAEDIYSYLLS 526
Query: 181 LEEEQAVRPKYLLGRE-VTGNMRAILIDWLVQVQMKFRLLQETMYMTVSIIDRFMQNNCV 239
+E + RP ++ +E VT MRAIL+DWLV+V +++L +ET+++TV+ IDRF+ + V
Sbjct: 527 VEHKNRPRPGFMKRQEDVTMAMRAILVDWLVEVAEEYKLQRETLFLTVTFIDRFLAHMSV 706
Query: 240 PKKMLQLVGVTAMFIASKYEEMYPPEIGDFAFVTDNTYTKHQIRQMEMKILRALNFGLGR 299
+ LQLVG AMF+A+KYEE+YPP++ +F ++TD+T K QI +ME IL+ L F +
Sbjct: 707 LRSKLQLVGAAAMFLAAKYEEIYPPDVNEFVYITDDTXQKKQILRMEHLILKVLKFDIST 886
Query: 300 PLPLHFLRRASKIGEVDVEQHTLAKYLMELTMLDYD-MVHFPPSQIAAGAFCLALKILDN 358
P F R + + + L YL EL +++Y+ + FP S +AA A CLA L
Sbjct: 887 PTVNWFSERLLRKVKAEDSLKNLTMYLCELVLVEYEKYLVFPNSLVAASALCLANYTLH- 1063
Query: 359 GEWTVKNKYATSKHAKIST 377
+ + +++H ++S+
Sbjct: 1064-----QQHFWSAEHERVSS 1105
>16444
Length = 2113
Score = 124 bits (310), Expect = 9e-29, Method: Compositional matrix adjust.
Identities = 74/200 (37%), Positives = 111/200 (55%), Gaps = 6/200 (3%)
Frame = -2
Query: 196 EVTGNMRAILIDWLVQVQMKFRLLQETMYMTVSIIDRFMQNNCVPKKMLQLVGVTAMFIA 255
E+T MR IL+DWLV++ +F + E +++ V I+DR++ V + LQLVG A F+A
Sbjct: 1227 ELTLTMRTILVDWLVELGDEFEVCHEGLFLAVKILDRYLAQVKVNRCNLQLVGAAAFFLA 1048
Query: 256 SKYEEMYPPEIGDFAFVTDNTYTKHQIRQMEMKILRALNFGLGRPLPLHFLRRASKIGEV 315
SKYEE+YPP + D A++TD+T T Q+ +ME +I L+ L P F +R K+
Sbjct: 1047 SKYEEIYPPCVEDIAYMTDDTCTARQVLRMERRIFVKLDHDLNGPSIGWFAQRLCKVTGS 868
Query: 316 DVEQHTLAKYLMELTMLDYD-MVHFPPSQIAAGAFCLALKIL-DNGEW----TVKNKYAT 369
L +L L L D + +PPS IAA AFCLA L D W +K++Y
Sbjct: 867 PENLEQLTMFLCYLAXLHIDXFLEYPPSIIAASAFCLARYTLRDRTPWDRLCVMKSQYYL 688
Query: 370 SKHAKISTLPQLNSALVQDL 389
H +S + +L +A ++
Sbjct: 687 --HELLSCIDELYAAYLESF 634
>19735
Length = 1559
Score = 36.6 bits (83), Expect = 0.019, Method: Compositional matrix adjust.
Identities = 26/102 (25%), Positives = 49/102 (48%), Gaps = 3/102 (2%)
Frame = -1
Query: 208 WLVQVQMKFRLLQETMYMTVSIIDRFMQNNCVPKKMLQLVGVTAMFIASKY---EEMYPP 264
W++Q F ET + +SI+DR + K L+ V ++ +FIA+K +E P
Sbjct: 1496 WIIQQSRSFDFAPETYALAISIMDRVSTLVKIRPKYLRCVAISCLFIAAKTLEDDETIPI 1317
Query: 265 EIGDFAFVTDNTYTKHQIRQMEMKILRALNFGLGRPLPLHFL 306
+ D + + ++ +ME+ IL L++ + + FL
Sbjct: 1316 TL-DLVRKSQCGCSVSEVLRMELVILTKLDWNVKTITTIDFL 1194
>31532
Length = 783
Score = 34.7 bits (78), Expect = 0.066, Method: Compositional matrix adjust.
Identities = 17/40 (42%), Positives = 26/40 (65%)
Frame = -1
Query: 351 LALKILDNGEWTVKNKYATSKHAKISTLPQLNSALVQDLA 390
L +K ++ + ++ KY+TSK KIS LP+L S L+ LA
Sbjct: 726 LVIKAQNSKQTAIREKYSTSKLMKISQLPELKSPLIAQLA 607
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000256442 | hsapiens_gene_ensembl |
G2/mitotic-specific cyclin-B1. [Source:Uniprot/SWISSPROT;Acc:P14635]
(433 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
25961 179 6e-59
11451 166 1e-41
16444 127 1e-29
19735 37 0.014
31532 34 0.095
38040 33 0.21
>25961
Length = 538
Score = 179 bits (454), Expect(2) = 6e-59, Method: Compositional matrix adjust.
Identities = 78/139 (56%), Positives = 101/139 (72%)
Frame = -1
Query: 163 DPNLCSEYVKDIYAYLRQLEEEQAVRPKYLLGREVTGNMRAILIDWLVQVQMKFRLLQET 222
+P L SEYV DIY Y+RQ+E+ VR YL G ++TG MR IL+DWL QV +F LLQET
Sbjct: 532 NPQLVSEYVNDIYDYMRQMEQRLCVRASYLEGTDITGKMRCILVDWLCQVHHRFHLLQET 353
Query: 223 MYMTVSIIDRFMQNNCVPKKMLQLVGVTAMFIASKYEEMYPPEIGDFAFVTDNTYTKHQI 282
+Y+TVSI+DRF+Q V + LQLVGVT+M +ASKYEE++ PE+ DF +++DN Y K I
Sbjct: 352 LYLTVSIMDRFLQQKPVTRNKLQLVGVTSMLVASKYEELFAPEVADFVYISDNAYAKADI 173
Query: 283 RQMEMKILRALNFGLGRPL 301
+ME ILR LNF G+P
Sbjct: 172 HEMERDILRTLNFSFGKPF 116
Score = 67.0 bits (162), Expect(2) = 6e-59, Method: Compositional matrix adjust.
Identities = 30/43 (69%), Positives = 36/43 (83%)
Frame = -2
Query: 297 LGRPLPLHFLRRASKIGEVDVEQHTLAKYLMELTMLDYDMVHF 339
LG L LHFLRR SK G+VD +HTLAKYLMELT+++YDMVH+
Sbjct: 129 LGNLLCLHFLRRNSKAGQVDAVKHTLAKYLMELTVIEYDMVHY 1
>11451
Length = 1321
Score = 166 bits (421), Expect = 1e-41, Method: Compositional matrix adjust.
Identities = 103/298 (34%), Positives = 162/298 (54%), Gaps = 6/298 (2%)
Frame = +2
Query: 124 TASPSPMETSGCAPAEEDLCQAFSDVILAVNDVDAEDGADPNLCSE---YVKDIYAYLRQ 180
T S ++ SG EE + +V + +V+ E + E Y +DIY+YL
Sbjct: 359 TEDSSYLDMSGVEDEEE----SEDNVSMGSEEVEEEPQDSATIIEEVPEYAEDIYSYLLS 526
Query: 181 LEEEQAVRPKYLLGRE-VTGNMRAILIDWLVQVQMKFRLLQETMYMTVSIIDRFMQNNCV 239
+E + RP ++ +E VT MRAIL+DWLV+V +++L +ET+++TV+ IDRF+ + V
Sbjct: 527 VEHKNRPRPGFMKRQEDVTMAMRAILVDWLVEVAEEYKLQRETLFLTVTFIDRFLAHMSV 706
Query: 240 PKKMLQLVGVTAMFIASKYEEMYPPEIGDFAFVTDNTYTKHQIRQMEMKILRALNFGLGR 299
+ LQLVG AMF+A+KYEE+YPP++ +F ++TD+T K QI +ME IL+ L F +
Sbjct: 707 LRSKLQLVGAAAMFLAAKYEEIYPPDVNEFVYITDDTXQKKQILRMEHLILKVLKFDIST 886
Query: 300 PLPLHFLRRASKIGEVDVEQHTLAKYLMELTMLDYD-MVHFPPSQIAAGAFCLALKILDN 358
P F R + + + L YL EL +++Y+ + FP S +AA A CLA L
Sbjct: 887 PTVNWFSERLLRKVKAEDSLKNLTMYLCELVLVEYEKYLVFPNSLVAASALCLANYTLHQ 1066
Query: 359 GE-WTPTLQHYLSYTEESLLPVMQHLAKNVVMVNQGLTKHMTVKNKYATSKHAKISTL 415
W+ + SY+ LLP +Q L + V+ KY SK+ ++ +
Sbjct: 1067QHFWSAEHERVSSYSLSQLLPCVQMLYDMHCHIEHH--PQQAVREKYRLSKYDSVADM 1234
>16444
Length = 2113
Score = 127 bits (318), Expect = 1e-29, Method: Compositional matrix adjust.
Identities = 77/223 (34%), Positives = 114/223 (51%), Gaps = 2/223 (0%)
Frame = -2
Query: 196 EVTGNMRAILIDWLVQVQMKFRLLQETMYMTVSIIDRFMQNNCVPKKMLQLVGVTAMFIA 255
E+T MR IL+DWLV++ +F + E +++ V I+DR++ V + LQLVG A F+A
Sbjct: 1227 ELTLTMRTILVDWLVELGDEFEVCHEGLFLAVKILDRYLAQVKVNRCNLQLVGAAAFFLA 1048
Query: 256 SKYEEMYPPEIGDFAFVTDNTYTKHQIRQMEMKILRALNFGLGRPLPLHFLRRASKIGEV 315
SKYEE+YPP + D A++TD+T T Q+ +ME +I L+ L P F +R K+
Sbjct: 1047 SKYEEIYPPCVEDIAYMTDDTCTARQVLRMERRIFVKLDHDLNGPSIGWFAQRLCKVTGS 868
Query: 316 DVEQHTLAKYLMELTMLDYD-MVHFPPSQIAAGAFCLALKIL-DNGEWTPTLQHYLSYTE 373
L +L L L D + +PPS IAA AFCLA L D W Y
Sbjct: 867 PENLEQLTMFLCYLAXLHIDXFLEYPPSIIAASAFCLARYTLRDRTPWDRLCVMKSQYYL 688
Query: 374 ESLLPVMQHLAKNVVMVNQGLTKHMTVKNKYATSKHAKISTLP 416
LL + L + Q ++ +NK+ + +S +P
Sbjct: 687 HELLSCIDELYAAYLESFQ--SQQQACQNKFGKERFGMVSRIP 565
>19735
Length = 1559
Score = 37.0 bits (84), Expect = 0.014, Method: Compositional matrix adjust.
Identities = 26/102 (25%), Positives = 49/102 (48%), Gaps = 3/102 (2%)
Frame = -1
Query: 208 WLVQVQMKFRLLQETMYMTVSIIDRFMQNNCVPKKMLQLVGVTAMFIASKY---EEMYPP 264
W++Q F ET + +SI+DR + K L+ V ++ +FIA+K +E P
Sbjct: 1496 WIIQQSRSFDFAPETYALAISIMDRVSTLVKIRPKYLRCVAISCLFIAAKTLEDDETIPI 1317
Query: 265 EIGDFAFVTDNTYTKHQIRQMEMKILRALNFGLGRPLPLHFL 306
+ D + + ++ +ME+ IL L++ + + FL
Sbjct: 1316 TL-DLVRKSQCGCSVSEVLRMELVILTKLDWNVKTITTIDFL 1194
>31532
Length = 783
Score = 34.3 bits (77), Expect = 0.095, Method: Compositional matrix adjust.
Identities = 16/33 (48%), Positives = 22/33 (66%)
Frame = -1
Query: 395 TKHMTVKNKYATSKHAKISTLPQLNSALVQDLA 427
+K ++ KY+TSK KIS LP+L S L+ LA
Sbjct: 705 SKQTAIREKYSTSKLMKISQLPELKSPLIAQLA 607
>38040
Length = 374
Score = 33.1 bits (74), Expect = 0.21, Method: Composition-based stats.
Identities = 20/73 (27%), Positives = 38/73 (52%)
Frame = +2
Query: 357 DNGEWTPTLQHYLSYTEESLLPVMQHLAKNVVMVNQGLTKHMTVKNKYATSKHAKISTLP 416
+ G WTPTL Y Y + L P++ L N ++ ++ +TV++KY +H ++
Sbjct: 2 EEGGWTPTLHFYTGYRLKELKPLILEL--NTMLCSKRYPDLVTVRDKY---RHHLFHSVA 166
Query: 417 QLNSALVQDLAKA 429
++ ++L KA
Sbjct: 167 EIAPVSNEELFKA 205
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000264126 | hsapiens_gene_ensembl |
G-protein-signaling modulator 2 (Mosaic protein LGN).
[Source:Uniprot/SWISSPROT;Acc:P81274]
(677 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
22872 173 6e-59
30597 109 3e-24
37021 35 0.14
34628 32 1.1
22644 30 3.3
>22872
Length = 459
Score = 173 bits (438), Expect(2) = 6e-59, Method: Compositional matrix adjust.
Identities = 82/110 (74%), Positives = 93/110 (84%)
Frame = +2
Query: 93 GEAKASGNLGNTLKVLGNFDEAIVCCQRHLDISRELNDKVGEARALYNLGNVYHAKGKSF 152
GEAKASGNLGNTLKV+G FDEAIVCC RHL+ISRELNDK+GEARALYNLGNV+H KGK
Sbjct: 128 GEAKASGNLGNTLKVIGKFDEAIVCCMRHLEISRELNDKLGEARALYNLGNVWHTKGKQM 307
Query: 153 GCPGPQDVGEFPEEVRDALQAAVDFYEENLSLVTALGDRAAQGRAFGNLG 202
G G QD GEFP +V++ LQ A FY++NLSLV LGD++AQGRA GNLG
Sbjct: 308 GRTGNQDPGEFPPQVKECLQKAAQFYQDNLSLVKELGDKSAQGRACGNLG 457
Score = 73.9 bits (180), Expect(2) = 6e-59, Method: Compositional matrix adjust.
Identities = 35/46 (76%), Positives = 39/46 (84%)
Frame = +3
Query: 51 LKTLSAIYSQLGNAYFYLHDYAKALEYHHHDLTLARTIGDQLGEAK 96
LKTL AIYSQLGNAYFYL DYAKALEYH HDL LART D++G+ +
Sbjct: 3 LKTLGAIYSQLGNAYFYLQDYAKALEYHKHDLNLARTCQDRVGKPR 140
Score = 58.5 bits (140), Expect(2) = 6e-14, Method: Compositional matrix adjust.
Identities = 36/109 (33%), Positives = 60/109 (55%), Gaps = 20/109 (18%)
Frame = +2
Query: 274 EAQSCYSLGNTYTLLQDYEKAIDYHLKHLAIAQELNDRIGEGRACWSLGNAYTA------ 327
EA++ +LGNT ++ +++AI ++HL I++ELND++GE RA ++LGN +
Sbjct: 131 EAKASGNLGNTLKVIGKFDEAIVCCMRHLEISRELNDKLGEARALYNLGNVWHTKGKQMG 310
Query: 328 -LGNHD-------------QAMHFAEKHLEISREVGDKSGELTARLNLS 362
GN D +A F + +L + +E+GDKS + A NL
Sbjct: 311 RTGNQDPGEFPPQVKECLQKAAQFYQDNLSLVKELGDKSAQGRACGNLG 457
Score = 37.4 bits (85), Expect(2) = 6e-14, Method: Compositional matrix adjust.
Identities = 18/35 (51%), Positives = 23/35 (65%)
Frame = +3
Query: 238 YSNLGNAYIFLGEFETASEYYKKTLLLARQLKDRA 272
YS LGNAY +L ++ A EY+K L LAR +DR
Sbjct: 24 YSQLGNAYFYLQDYAKALEYHKHDLNLARTCQDRV 128
Score = 45.4 bits (106), Expect(2) = 7e-11, Method: Compositional matrix adjust.
Identities = 24/57 (42%), Positives = 33/57 (57%)
Frame = +2
Query: 313 GEGRACWSLGNAYTALGNHDQAMHFAEKHLEISREVGDKSGELTARLNLSDLQMVLG 369
GE +A +LGN +G D+A+ +HLEISRE+ DK GE A NL ++ G
Sbjct: 128 GEAKASGNLGNTLKVIGKFDEAIVCCMRHLEISRELNDKLGEARALYNLGNVWHTKG 298
Score = 40.0 bits (92), Expect(2) = 7e-11, Method: Compositional matrix adjust.
Identities = 18/36 (50%), Positives = 24/36 (66%)
Frame = +3
Query: 281 LGNTYTLLQDYEKAIDYHLKHLAIAQELNDRIGEGR 316
LGN Y LQDY KA++YH L +A+ DR+G+ R
Sbjct: 33 LGNAYFYLQDYAKALEYHKHDLNLARTCQDRVGKPR 140
Score = 59.3 bits (142), Expect = 6e-09, Method: Compositional matrix adjust.
Identities = 32/111 (28%), Positives = 57/111 (51%), Gaps = 20/111 (18%)
Frame = +2
Query: 192 AAQGRAFGNLGNTHYLLGNFRDAVIAHEQRLLIAKEFGDKAAERRAYSNLGNAYIFLGE- 250
+ +A GNLGNT ++G F +A++ + L I++E DK E RA NLGN + G+
Sbjct: 125 GGEAKASGNLGNTLKVIGKFDEAIVCCMRHLEISRELNDKLGEARALYNLGNVWHTKGKQ 304
Query: 251 -------------------FETASEYYKKTLLLARQLKDRAVEAQSCYSLG 282
+ A+++Y+ L L ++L D++ + ++C +LG
Sbjct: 305 MGRTGNQDPGEFPPQVKECLQKAAQFYQDNLSLVKELGDKSAQGRACGNLG 457
Score = 54.7 bits (130), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 35/118 (29%), Positives = 59/118 (50%), Gaps = 20/118 (16%)
Frame = +2
Query: 225 AKEFGDKAAERRAYSNLGNAYIFLGEFETASEYYKKTLLLARQLKDRAVEAQSCYSLGNT 284
K+ E +A NLGN +G+F+ A + L ++R+L D+ EA++ Y+LGN
Sbjct: 104 GKDVSGPGGEAKASGNLGNTLKVIGKFDEAIVCCMRHLEISRELNDKLGEARALYNLGNV 283
Query: 285 Y---------TLLQD-----------YEKAIDYHLKHLAIAQELNDRIGEGRACWSLG 322
+ T QD +KA ++ +L++ +EL D+ +GRAC +LG
Sbjct: 284 WHTKGKQMGRTGNQDPGEFPPQVKECLQKAAQFYQDNLSLVKELGDKSAQGRACGNLG 457
Score = 38.1 bits (87), Expect = 0.011, Method: Compositional matrix adjust.
Identities = 30/102 (29%), Positives = 44/102 (43%), Gaps = 20/102 (19%)
Frame = +2
Query: 61 LGNAYFYLHDYAKALEYHHHDLTLARTIGDQLGEAKASGNLGNTLKVLGN---------- 110
LGN + + +A+ L ++R + D+LGEA+A NLGN G
Sbjct: 152 LGNTLKVIGKFDEAIVCCMRHLEISRELNDKLGEARALYNLGNVWHTKGKQMGRTGNQDP 331
Query: 111 --FDEAIVCC--------QRHLDISRELNDKVGEARALYNLG 142
F + C Q +L + +EL DK + RA NLG
Sbjct: 332 GEFPPQVKECLQKAAQFYQDNLSLVKELGDKSAQGRACGNLG 457
>30597
Length = 734
Score = 109 bits (273), Expect = 3e-24, Method: Compositional matrix adjust.
Identities = 51/96 (53%), Positives = 73/96 (76%)
Frame = +3
Query: 319 WSLGNAYTALGNHDQAMHFAEKHLEISREVGDKSGELTARLNLSDLQMVLGLSYSTNNSI 378
WSLGNA++ALGNH+ A+ FA KHLEIS+E+GD++G++TA++N++D + +LG+ + S
Sbjct: 3 WSLGNAHSALGNHESALEFANKHLEISKEIGDETGQMTAQMNMTDFRAMLGMIPVADKSG 182
Query: 379 MSENTEIDSSLNGVRPKLGRRHSMENMELMKLTPEK 414
SE D +L RP+ RR SMENME+MKLTP+K
Sbjct: 183 RSETDTADVALK--RPERARRFSMENMEIMKLTPDK 284
Score = 66.2 bits (160), Expect = 4e-11, Method: Compositional matrix adjust.
Identities = 41/101 (40%), Positives = 55/101 (54%)
Frame = +1
Query: 480 IGDEGFFDLLSRFQSNRMDDQRCCLQEKNCHXXXXXXXXXPPKMMLKTSSVPVVSPNTDE 539
+ D+GFFD LSRFQS R+DDQRC + K + + V SP +E
Sbjct: 421 LDDDGFFDQLSRFQSRRIDDQRCSFRLLESGATSPTHSSQDCKDL----AALVASPAREE 588
Query: 540 FLDLLASSQSRRLDDQRASFSNLPGLRLTQNSQSVLSHLMT 580
+DL+A Q R++DQRAS + PGL NS V+S L+T
Sbjct: 589 LMDLVAGFQVSRMNDQRASLPSFPGL----NSGDVISQLLT 699
Score = 40.8 bits (94), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 28/104 (26%), Positives = 46/104 (44%), Gaps = 4/104 (3%)
Frame = +3
Query: 100 NLGNTLKVLGNFDEAIVCCQRHLDISRELNDKVGEARALYNLGNVYHAKGKSFGCPGPQD 159
+LGN LGN + A+ +HL+IS+E+ D+ G+ A N+ + G P
Sbjct: 6 SLGNAHSALGNHESALEFANKHLEISKEIGDETGQMTAQMNMTDFRAMLGM---IPVADK 176
Query: 160 VGEFPEEVRDAL----QAAVDFYEENLSLVTALGDRAAQGRAFG 199
G + D + A F EN+ ++ D+ GR +G
Sbjct: 177 SGRSETDTADVALKRPERARRFSMENMEIMKLTPDKKG*GRGWG 308
Score = 35.0 bits (79), Expect = 0.11, Method: Compositional matrix adjust.
Identities = 17/49 (34%), Positives = 30/49 (61%)
Frame = +3
Query: 61 LGNAYFYLHDYAKALEYHHHDLTLARTIGDQLGEAKASGNLGNTLKVLG 109
LGNA+ L ++ ALE+ + L +++ IGD+ G+ A N+ + +LG
Sbjct: 9 LGNAHSALGNHESALEFANKHLEISKEIGDETGQMTAQMNMTDFRAMLG 155
Score = 34.3 bits (77), Expect = 0.18, Method: Compositional matrix adjust.
Identities = 19/55 (34%), Positives = 27/55 (49%)
Frame = +3
Query: 200 NLGNTHYLLGNFRDAVIAHEQRLLIAKEFGDKAAERRAYSNLGNAYIFLGEFETA 254
+LGN H LGN A+ + L I+KE GD+ + A N+ + LG A
Sbjct: 6 SLGNAHSALGNHESALEFANKHLEISKEIGDETGQMTAQMNMTDFRAMLGMIPVA 170
Score = 29.6 bits (65), Expect = 4.0, Method: Compositional matrix adjust.
Identities = 12/22 (54%), Positives = 16/22 (72%)
Frame = +1
Query: 587 DEDFFDILVKCQGSRLDDQRCA 608
D+ FFD L + Q R+DDQRC+
Sbjct: 427 DDGFFDQLSRFQSRRIDDQRCS 492
>37021
Length = 232
Score = 34.7 bits (78), Expect = 0.14, Method: Composition-based stats.
Identities = 13/16 (81%), Positives = 14/16 (87%)
Frame = +1
Query: 24 GERLCKSGDCRAGVSF 39
G RLCK+GDCRAGV F
Sbjct: 184 GGRLCKAGDCRAGVQF 231
>34628
Length = 545
Score = 31.6 bits (70), Expect = 1.1, Method: Composition-based stats.
Identities = 24/88 (27%), Positives = 47/88 (53%), Gaps = 7/88 (7%)
Frame = +1
Query: 246 IFLGEFETASEYYKKTLLLARQLKDRAVE------AQSCYSLGNTYTLLQDYEKAIDYHL 299
I + ++++A Y ++ AR ++D E + + LG +T+ D +KAI+ +
Sbjct: 4 ISMKQYQSAVHYLEQ----ARDIQDVLEEDIKGDLVSTLHQLGQMHTMAGDIDKAIESYR 171
Query: 300 KHLAIAQEL-NDRIGEGRACWSLGNAYT 326
+ L + +E+ ND++G C +LGN T
Sbjct: 172 ESLDVFREMHNDQLGP-EMCVTLGNLAT 252
Score = 28.9 bits (63), Expect = 6.2, Method: Composition-based stats.
Identities = 27/73 (36%), Positives = 38/73 (52%), Gaps = 8/73 (10%)
Frame = +1
Query: 80 HDLTLARTIGDQLGEAKASGNLGNTLKVLG-------NFDEAIVCCQRHLDISREL-NDK 131
H L AR I D L E G+L +TL LG + D+AI + LD+ RE+ ND+
Sbjct: 34 HYLEQARDIQDVL-EEDIKGDLVSTLHQLGQMHTMAGDIDKAIESYRESLDVFREMHNDQ 210
Query: 132 VGEARALYNLGNV 144
+G + LGN+
Sbjct: 211 LGPEMCV-TLGNL 246
>22644
Length = 1600
Score = 30.0 bits (66), Expect = 3.3, Method: Compositional matrix adjust.
Identities = 14/59 (23%), Positives = 35/59 (59%)
Frame = +1
Query: 238 YSNLGNAYIFLGEFETASEYYKKTLLLARQLKDRAVEAQSCYSLGNTYTLLQDYEKAID 296
+S LGNAY+ + + A +++ + + ++ + + +++ +LG T+ +D+ KA+D
Sbjct: 934 HSLLGNAYLEVRDLGNAFKHHSEDFRIGQEKQYPNITSRALANLGRTHVFRKDFTKALD 1110
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000359004 | hsapiens_gene_ensembl |
G-protein-signaling modulator 2 (Mosaic protein LGN).
[Source:Uniprot/SWISSPROT;Acc:P81274]
(684 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
22872 173 6e-59
30597 109 3e-24
37021 35 0.13
34628 32 1.2
22644 30 3.2
>22872
Length = 459
Score = 173 bits (438), Expect(2) = 6e-59, Method: Compositional matrix adjust.
Identities = 82/110 (74%), Positives = 93/110 (84%)
Frame = +2
Query: 100 GEAKASGNLGNTLKVLGNFDEAIVCCQRHLDISRELNDKVGEARALYNLGNVYHAKGKSF 159
GEAKASGNLGNTLKV+G FDEAIVCC RHL+ISRELNDK+GEARALYNLGNV+H KGK
Sbjct: 128 GEAKASGNLGNTLKVIGKFDEAIVCCMRHLEISRELNDKLGEARALYNLGNVWHTKGKQM 307
Query: 160 GCPGPQDVGEFPEEVRDALQAAVDFYEENLSLVTALGDRAAQGRAFGNLG 209
G G QD GEFP +V++ LQ A FY++NLSLV LGD++AQGRA GNLG
Sbjct: 308 GRTGNQDPGEFPPQVKECLQKAAQFYQDNLSLVKELGDKSAQGRACGNLG 457
Score = 73.9 bits (180), Expect(2) = 6e-59, Method: Compositional matrix adjust.
Identities = 35/46 (76%), Positives = 39/46 (84%)
Frame = +3
Query: 58 LKTLSAIYSQLGNAYFYLHDYAKALEYHHHDLTLARTIGDQLGEAK 103
LKTL AIYSQLGNAYFYL DYAKALEYH HDL LART D++G+ +
Sbjct: 3 LKTLGAIYSQLGNAYFYLQDYAKALEYHKHDLNLARTCQDRVGKPR 140
Score = 58.5 bits (140), Expect(2) = 6e-14, Method: Compositional matrix adjust.
Identities = 36/109 (33%), Positives = 60/109 (55%), Gaps = 20/109 (18%)
Frame = +2
Query: 281 EAQSCYSLGNTYTLLQDYEKAIDYHLKHLAIAQELNDRIGEGRACWSLGNAYTA------ 334
EA++ +LGNT ++ +++AI ++HL I++ELND++GE RA ++LGN +
Sbjct: 131 EAKASGNLGNTLKVIGKFDEAIVCCMRHLEISRELNDKLGEARALYNLGNVWHTKGKQMG 310
Query: 335 -LGNHD-------------QAMHFAEKHLEISREVGDKSGELTARLNLS 369
GN D +A F + +L + +E+GDKS + A NL
Sbjct: 311 RTGNQDPGEFPPQVKECLQKAAQFYQDNLSLVKELGDKSAQGRACGNLG 457
Score = 37.4 bits (85), Expect(2) = 6e-14, Method: Compositional matrix adjust.
Identities = 18/35 (51%), Positives = 23/35 (65%)
Frame = +3
Query: 245 YSNLGNAYIFLGEFETASEYYKKTLLLARQLKDRA 279
YS LGNAY +L ++ A EY+K L LAR +DR
Sbjct: 24 YSQLGNAYFYLQDYAKALEYHKHDLNLARTCQDRV 128
Score = 45.1 bits (105), Expect(2) = 8e-11, Method: Compositional matrix adjust.
Identities = 24/57 (42%), Positives = 33/57 (57%)
Frame = +2
Query: 320 GEGRACWSLGNAYTALGNHDQAMHFAEKHLEISREVGDKSGELTARLNLSDLQMVLG 376
GE +A +LGN +G D+A+ +HLEISRE+ DK GE A NL ++ G
Sbjct: 128 GEAKASGNLGNTLKVIGKFDEAIVCCMRHLEISRELNDKLGEARALYNLGNVWHTKG 298
Score = 40.0 bits (92), Expect(2) = 8e-11, Method: Compositional matrix adjust.
Identities = 18/36 (50%), Positives = 24/36 (66%)
Frame = +3
Query: 288 LGNTYTLLQDYEKAIDYHLKHLAIAQELNDRIGEGR 323
LGN Y LQDY KA++YH L +A+ DR+G+ R
Sbjct: 33 LGNAYFYLQDYAKALEYHKHDLNLARTCQDRVGKPR 140
Score = 58.9 bits (141), Expect = 6e-09, Method: Compositional matrix adjust.
Identities = 32/111 (28%), Positives = 57/111 (51%), Gaps = 20/111 (18%)
Frame = +2
Query: 199 AAQGRAFGNLGNTHYLLGNFRDAVIAHEQRLLIAKEFGDKAAERRAYSNLGNAYIFLGE- 257
+ +A GNLGNT ++G F +A++ + L I++E DK E RA NLGN + G+
Sbjct: 125 GGEAKASGNLGNTLKVIGKFDEAIVCCMRHLEISRELNDKLGEARALYNLGNVWHTKGKQ 304
Query: 258 -------------------FETASEYYKKTLLLARQLKDRAVEAQSCYSLG 289
+ A+++Y+ L L ++L D++ + ++C +LG
Sbjct: 305 MGRTGNQDPGEFPPQVKECLQKAAQFYQDNLSLVKELGDKSAQGRACGNLG 457
Score = 54.7 bits (130), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 35/118 (29%), Positives = 59/118 (50%), Gaps = 20/118 (16%)
Frame = +2
Query: 232 AKEFGDKAAERRAYSNLGNAYIFLGEFETASEYYKKTLLLARQLKDRAVEAQSCYSLGNT 291
K+ E +A NLGN +G+F+ A + L ++R+L D+ EA++ Y+LGN
Sbjct: 104 GKDVSGPGGEAKASGNLGNTLKVIGKFDEAIVCCMRHLEISRELNDKLGEARALYNLGNV 283
Query: 292 Y---------TLLQD-----------YEKAIDYHLKHLAIAQELNDRIGEGRACWSLG 329
+ T QD +KA ++ +L++ +EL D+ +GRAC +LG
Sbjct: 284 WHTKGKQMGRTGNQDPGEFPPQVKECLQKAAQFYQDNLSLVKELGDKSAQGRACGNLG 457
Score = 38.1 bits (87), Expect = 0.011, Method: Compositional matrix adjust.
Identities = 30/102 (29%), Positives = 44/102 (43%), Gaps = 20/102 (19%)
Frame = +2
Query: 68 LGNAYFYLHDYAKALEYHHHDLTLARTIGDQLGEAKASGNLGNTLKVLGN---------- 117
LGN + + +A+ L ++R + D+LGEA+A NLGN G
Sbjct: 152 LGNTLKVIGKFDEAIVCCMRHLEISRELNDKLGEARALYNLGNVWHTKGKQMGRTGNQDP 331
Query: 118 --FDEAIVCC--------QRHLDISRELNDKVGEARALYNLG 149
F + C Q +L + +EL DK + RA NLG
Sbjct: 332 GEFPPQVKECLQKAAQFYQDNLSLVKELGDKSAQGRACGNLG 457
>30597
Length = 734
Score = 109 bits (273), Expect = 3e-24, Method: Compositional matrix adjust.
Identities = 51/96 (53%), Positives = 73/96 (76%)
Frame = +3
Query: 326 WSLGNAYTALGNHDQAMHFAEKHLEISREVGDKSGELTARLNLSDLQMVLGLSYSTNNSI 385
WSLGNA++ALGNH+ A+ FA KHLEIS+E+GD++G++TA++N++D + +LG+ + S
Sbjct: 3 WSLGNAHSALGNHESALEFANKHLEISKEIGDETGQMTAQMNMTDFRAMLGMIPVADKSG 182
Query: 386 MSENTEIDSSLNGVRPKLGRRHSMENMELMKLTPEK 421
SE D +L RP+ RR SMENME+MKLTP+K
Sbjct: 183 RSETDTADVALK--RPERARRFSMENMEIMKLTPDK 284
Score = 66.6 bits (161), Expect = 3e-11, Method: Compositional matrix adjust.
Identities = 41/101 (40%), Positives = 55/101 (54%)
Frame = +1
Query: 487 IGDEGFFDLLSRFQSNRMDDQRCCLQEKNCHXXXXXXXXXPPKMMLKTSSVPVVSPNTDE 546
+ D+GFFD LSRFQS R+DDQRC + K + + V SP +E
Sbjct: 421 LDDDGFFDQLSRFQSRRIDDQRCSFRLLESGATSPTHSSQDCKDL----AALVASPAREE 588
Query: 547 FLDLLASSQSRRLDDQRASFSNLPGLRLTQNSQSVLSHLMT 587
+DL+A Q R++DQRAS + PGL NS V+S L+T
Sbjct: 589 LMDLVAGFQVSRMNDQRASLPSFPGL----NSGDVISQLLT 699
Score = 40.8 bits (94), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 28/104 (26%), Positives = 46/104 (44%), Gaps = 4/104 (3%)
Frame = +3
Query: 107 NLGNTLKVLGNFDEAIVCCQRHLDISRELNDKVGEARALYNLGNVYHAKGKSFGCPGPQD 166
+LGN LGN + A+ +HL+IS+E+ D+ G+ A N+ + G P
Sbjct: 6 SLGNAHSALGNHESALEFANKHLEISKEIGDETGQMTAQMNMTDFRAMLGM---IPVADK 176
Query: 167 VGEFPEEVRDAL----QAAVDFYEENLSLVTALGDRAAQGRAFG 206
G + D + A F EN+ ++ D+ GR +G
Sbjct: 177 SGRSETDTADVALKRPERARRFSMENMEIMKLTPDKKG*GRGWG 308
Score = 34.7 bits (78), Expect = 0.12, Method: Compositional matrix adjust.
Identities = 17/49 (34%), Positives = 30/49 (61%)
Frame = +3
Query: 68 LGNAYFYLHDYAKALEYHHHDLTLARTIGDQLGEAKASGNLGNTLKVLG 116
LGNA+ L ++ ALE+ + L +++ IGD+ G+ A N+ + +LG
Sbjct: 9 LGNAHSALGNHESALEFANKHLEISKEIGDETGQMTAQMNMTDFRAMLG 155
Score = 34.3 bits (77), Expect = 0.19, Method: Compositional matrix adjust.
Identities = 19/55 (34%), Positives = 27/55 (49%)
Frame = +3
Query: 207 NLGNTHYLLGNFRDAVIAHEQRLLIAKEFGDKAAERRAYSNLGNAYIFLGEFETA 261
+LGN H LGN A+ + L I+KE GD+ + A N+ + LG A
Sbjct: 6 SLGNAHSALGNHESALEFANKHLEISKEIGDETGQMTAQMNMTDFRAMLGMIPVA 170
Score = 29.6 bits (65), Expect = 3.9, Method: Compositional matrix adjust.
Identities = 12/22 (54%), Positives = 16/22 (72%)
Frame = +1
Query: 594 DEDFFDILVKCQGSRLDDQRCA 615
D+ FFD L + Q R+DDQRC+
Sbjct: 427 DDGFFDQLSRFQSRRIDDQRCS 492
>37021
Length = 232
Score = 34.7 bits (78), Expect = 0.13, Method: Composition-based stats.
Identities = 13/16 (81%), Positives = 14/16 (87%)
Frame = +1
Query: 31 GERLCKSGDCRAGVSF 46
G RLCK+GDCRAGV F
Sbjct: 184 GGRLCKAGDCRAGVQF 231
>34628
Length = 545
Score = 31.6 bits (70), Expect = 1.2, Method: Composition-based stats.
Identities = 24/88 (27%), Positives = 47/88 (53%), Gaps = 7/88 (7%)
Frame = +1
Query: 253 IFLGEFETASEYYKKTLLLARQLKDRAVE------AQSCYSLGNTYTLLQDYEKAIDYHL 306
I + ++++A Y ++ AR ++D E + + LG +T+ D +KAI+ +
Sbjct: 4 ISMKQYQSAVHYLEQ----ARDIQDVLEEDIKGDLVSTLHQLGQMHTMAGDIDKAIESYR 171
Query: 307 KHLAIAQEL-NDRIGEGRACWSLGNAYT 333
+ L + +E+ ND++G C +LGN T
Sbjct: 172 ESLDVFREMHNDQLGP-EMCVTLGNLAT 252
Score = 28.9 bits (63), Expect = 6.9, Method: Composition-based stats.
Identities = 27/73 (36%), Positives = 38/73 (52%), Gaps = 8/73 (10%)
Frame = +1
Query: 87 HDLTLARTIGDQLGEAKASGNLGNTLKVLG-------NFDEAIVCCQRHLDISREL-NDK 138
H L AR I D L E G+L +TL LG + D+AI + LD+ RE+ ND+
Sbjct: 34 HYLEQARDIQDVL-EEDIKGDLVSTLHQLGQMHTMAGDIDKAIESYRESLDVFREMHNDQ 210
Query: 139 VGEARALYNLGNV 151
+G + LGN+
Sbjct: 211 LGPEMCV-TLGNL 246
>22644
Length = 1600
Score = 30.0 bits (66), Expect = 3.2, Method: Compositional matrix adjust.
Identities = 14/59 (23%), Positives = 35/59 (59%)
Frame = +1
Query: 245 YSNLGNAYIFLGEFETASEYYKKTLLLARQLKDRAVEAQSCYSLGNTYTLLQDYEKAID 303
+S LGNAY+ + + A +++ + + ++ + + +++ +LG T+ +D+ KA+D
Sbjct: 934 HSLLGNAYLEVRDLGNAFKHHSEDFRIGQEKQYPNITSRALANLGRTHVFRKDFTKALD 1110
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000335106 | hsapiens_gene_ensembl | Katanin p60
ATPase-containing subunit A1 (EC 3.6.4.3) (Katanin p60 subunit A1)
(p60 katanin). [Source:Uniprot/SWISSPROT;Acc:O75449]
(491 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
25671 187 1e-57
20270 157 4e-47
07243 157 6e-39
03022 145 3e-35
01642 140 1e-33
02582 139 2e-33
00810 134 9e-32
23766 129 7e-31
19129 130 1e-30
07247 124 1e-28
38672 81 1e-21
12235 82 5e-16
06766 65 5e-11
26408 56 4e-08
17843 54 2e-07
15498 49 6e-06
19561 37 0.014
01279 36 0.044
22221 32 0.45
08000 30 2.5
18409 30 3.0
27434 29 3.7
22754 28 5.8
>25671
Length = 441
Score = 187 bits (475), Expect(2) = 1e-57, Method: Composition-based stats.
Identities = 92/110 (83%), Positives = 101/110 (91%)
Frame = +2
Query: 253 TGKTLLAKAVATECKTTFFNVSSSTLTSKYRGESEKLVRLLFEMARFYSPATIFIDEIDS 312
TGKT+LAKAVATEC TTFFNVS+S+L +KYRGESEKLVRLLFEMA FY+P+TIFIDEIDS
Sbjct: 2 TGKTMLAKAVATECGTTFFNVSTSSLANKYRGESEKLVRLLFEMAHFYAPSTIFIDEIDS 181
Query: 313 ICSRRGTSEEHEASRRVKAELLVQMDGVGGTSENDDPSKMVMVLAATNFP 362
ICS+RG+ EHEASRRVK+ELLVQMDGVG T NDDPSK VMVLAATNFP
Sbjct: 182 ICSKRGSDSEHEASRRVKSELLVQMDGVGVT--NDDPSKAVMVLAATNFP 325
Score = 54.3 bits (129), Expect(2) = 1e-57, Method: Compositional matrix adjust.
Identities = 24/25 (96%), Positives = 25/25 (100%)
Frame = +3
Query: 362 PWDIDEALRRRLEKRIYIPLPSAKG 386
PWDIDEALRRRLEKRIYIPLPSA+G
Sbjct: 324 PWDIDEALRRRLEKRIYIPLPSAEG 398
>20270
Length = 542
Score = 157 bits (397), Expect(2) = 4e-47, Method: Compositional matrix adjust.
Identities = 78/136 (57%), Positives = 101/136 (74%), Gaps = 1/136 (0%)
Frame = -3
Query: 240 RPWKGVLMVGPPGTGKTLLAKAVATECK-TTFFNVSSSTLTSKYRGESEKLVRLLFEMAR 298
+PW+G+L+ GPPGTGK+ LAKAVATE +TFF+VSSS L SK+ GESEKLV+ LF++AR
Sbjct: 387 KPWRGILLYGPPGTGKSYLAKAVATEANNSTFFSVSSSDLVSKWLGESEKLVKTLFQLAR 208
Query: 299 FYSPATIFIDEIDSICSRRGTSEEHEASRRVKAELLVQMDGVGGTSENDDPSKMVMVLAA 358
P+ IFIDE+D++C R + E E++RR+K E LVQM GVG ND+ V+VL A
Sbjct: 207 ENQPSIIFIDEVDALCGSR-SENESESARRIKTEFLVQMQGVG----NDNTG--VLVLGA 49
Query: 359 TNFPWDIDEALRRRLE 374
TN PW +D A+RRR E
Sbjct: 48 TNIPWTLDSAIRRRFE 1
Score = 49.7 bits (117), Expect(2) = 4e-47, Method: Compositional matrix adjust.
Identities = 23/43 (53%), Positives = 28/43 (65%)
Frame = -1
Query: 197 RDIISQNPNVRWDDIADLVEAKKLLKEAVVLPMWMPEFFKGIR 239
R + + PNVRWDD+A L AK LKEAV+LP+ P F G R
Sbjct: 515 RSHVVEKPNVRWDDVAGLNGAKDALKEAVILPVKFPHLFTGKR 387
>07243
Length = 1112
Score = 157 bits (398), Expect = 6e-39, Method: Compositional matrix adjust.
Identities = 100/251 (39%), Positives = 142/251 (56%), Gaps = 8/251 (3%)
Frame = +1
Query: 192 VEALERDIISQNP-NVRWDDIADLVEAKKLLKEAVVLPMWMPEFF--KGIRRPWKGVLMV 248
V+ L ++ ++P +V + I L E + L+E + LP+ PE F GI P KG L+
Sbjct: 151 VDPLVYNMSHEDPGDVTYSAIGGLTEQIRELREVIELPLLNPELFLRVGIT-PPKGCLLY 327
Query: 249 GPPGTGKTLLAKAVATECKTTFFNVSSSTLTSKYRGESEKLVRLLFEMARFYSPATIFID 308
GPPGTGKTLLA+AVA++ F V SS + KY GES +L+R +F AR + P IF+D
Sbjct: 328 GPPGTGKTLLARAVASQLDANFLKVVSSAIVDKYIGESARLIREMFNYARDHQPCIIFMD 507
Query: 309 EIDSICSRR---GTSEEHEASRRVKAELLVQMDGVGGTSENDDPSKMVMVLAATNFPWDI 365
EID+I RR GTS + E R + ELL QMDG + KM+M ATN P +
Sbjct: 508 EIDAIGGRRFSEGTSADREIQRTL-MELLNQMDGFDSLGQ----VKMIM---ATNRPDTL 663
Query: 366 DEALRR--RLEKRIYIPLPSAKGXXXXXXXXXXXXXXADDVDLASIAENMEGYSGADITN 423
D AL R RL+++I IPLP+ + ++D +I + + ++GAD+ N
Sbjct: 664 DPALLRPGRLDRKIEIPLPNEQARLEILKIHALIIAKHGEIDYEAIVKLSDNFNGADLRN 843
Query: 424 VCRDASLMAMR 434
VC +A L A+R
Sbjct: 844 VCTEAGLFAIR 876
>03022
Length = 2255
Score = 145 bits (366), Expect = 3e-35, Method: Compositional matrix adjust.
Identities = 98/314 (31%), Positives = 159/314 (50%), Gaps = 5/314 (1%)
Frame = +2
Query: 165 EEKNKSPAAVTEPETNKFDSTGYDKDLVEALERDIISQNPNVRWDDIADLVEAKKLLKEA 224
+E++ + A+TE D G K A +R+ + P W+D+ L + LK++
Sbjct: 1310 QEQDIAAVALTEE-----DFMGALKKAQPAAKREGFATVPTTTWEDVGALSNVRAQLKDS 1474
Query: 225 VVLPMWMPEFFKGIRRPWK-GVLMVGPPGTGKTLLAKAVATECKTTFFNVSSSTLTSKYR 283
++ + PE P G+++VGPPG GKTL+AKA+A E F + L KY
Sbjct: 1475 ILCRIHDPEVSSAFGLPTNSGIILVGPPGCGKTLVAKAMANEAGLNFIYIKGPELLDKYV 1654
Query: 284 GESEKLVRLLFEMARFYSPATIFIDEIDSICSRRGTSEEHEASRRVKAELLVQMDGVGGT 343
GESE+ +R F+ A+ +P IF DE+D++CS R ++ + V +LL MDG G
Sbjct: 1655 GESERNLREKFDKAQACAPCLIFFDEMDTLCSNRQNNDGSNVGKSVTNQLLALMDGCGER 1834
Query: 344 SENDDPSKMVMVLAATNFPWDIDEALRR--RLEKRIYIPLPSAKGXX--XXXXXXXXXXX 399
S+ V V+ ATN ++D AL+R R +++I+I LP G
Sbjct: 1835 SQ-------VYVMGATNIIENVDPALQRPGRFDRKIFIGLPDTDGRLDILRALTKGGSQR 1993
Query: 400 XADDVDLASIAENMEGYSGADITNVCRDASLMAMRRRIEGLTPEEIRNLSKEEMHMPTTM 459
+ D+ +A++ EG+SGAD+ ++ +AS +A++ E + + R S E + T
Sbjct: 1994 KLESCDMQQLAQDTEGFSGADLKHLVNEASTIALK---ESMADQAWREDSHREYVV--TG 2158
Query: 460 EDFEMALKKVSKSV 473
+ F AL+ V SV
Sbjct: 2159 DQFTRALQLVKPSV 2200
>01642
Length = 1406
Score = 140 bits (352), Expect = 1e-33, Method: Compositional matrix adjust.
Identities = 90/241 (37%), Positives = 130/241 (53%), Gaps = 6/241 (2%)
Frame = -1
Query: 200 ISQNPNVRWDDIADLVEAKKLLKEAVVLPMWMPEFFKGIR-RPWKGVLMVGPPGTGKTLL 258
+ ++P + DI + K+ ++EAV LP+ E +K I P +GVLM GPPG GKT+L
Sbjct: 1022 LMRSPT*XYSDIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTML 843
Query: 259 AKAVATECKTTFFNVSSSTLTSKYRGESEKLVRLLFEMARFYSPATIFIDEIDSICSRR- 317
AKAVA F V S KY GE ++VR +F +A+ +PA IFIDEID+I ++R
Sbjct: 842 AKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRF 663
Query: 318 --GTSEEHEASRRVKAELLVQMDGVGGTSENDDPSKMVMVLAATNFPWDIDEALRR--RL 373
T + E +R+ ELL QMDG D + V V+ ATN +D AL R RL
Sbjct: 662 DAQTGADREV-QRILLELLNQMDGF-------DQTVNVKVIMATNRADTLDPALLRPGRL 507
Query: 374 EKRIYIPLPSAKGXXXXXXXXXXXXXXADDVDLASIAENMEGYSGADITNVCRDASLMAM 433
+++I PLP + +++VDL + SGADI +C++A + A+
Sbjct: 506 DRKIEFPLPDRRQKRLIFSTITGKMNISEEVDLEDYVARPDKISGADINAICQEAGMQAV 327
Query: 434 R 434
R
Sbjct: 326 R 324
>02582
Length = 1101
Score = 139 bits (351), Expect = 2e-33, Method: Compositional matrix adjust.
Identities = 92/266 (34%), Positives = 141/266 (53%), Gaps = 29/266 (10%)
Frame = +3
Query: 198 DIISQNPNVRWDDIADLVEAKKLLKEAVVLPMWMPEFFKGIRRPW-KGVLMVGPPGTGKT 256
D I +V W DI L K +++AV P+ P+ F+ + P KGVL+ GPPG GKT
Sbjct: 108 DCIVDARSVPWTDIGGLDLVKLQIRQAVEWPLLYPDTFQALGLPLTKGVLLYGPPGCGKT 287
Query: 257 LLAKAVATECKTTFFNVSSSTLTSKYRGESEKLVRLLFEMARFYSPATIFIDEIDSICSR 316
LA+A AT C TF ++S + L S Y G++EK + F+ AR +P+ +F+DE+D+I +
Sbjct: 288 TLAQAAATACHVTFLSLSCAQLYSPYVGDAEKKISETFQKARALAPSILFLDEMDAIVGK 467
Query: 317 RGTSEEHEA-SRRVKAELLVQMDGVG---------------GTSEN----------DDPS 350
R S S RV + LL +MDG+G G+S++ +
Sbjct: 468 RSDSSLGSGVSERVLSALLNEMDGIGVRLDDKSDSREMEIEGSSDHTPQVRQHAVKEAHD 647
Query: 351 KMVMVLAATNFPWDIDEALRR--RLEKRIYIPLPSAKGXXXXXXXXXXXXXXADDVDLAS 408
+ V+V+AATN P +D AL R R+++ IY+P P +G DVD+
Sbjct: 648 RHVLVVAATNRPDMLDPALLRPGRMDRLIYVPPPDVQGRLQSFTIHTRKMPLGKDVDVKQ 827
Query: 409 IAENMEGYSGADITNVCRDASLMAMR 434
+A+ GY+GADI +C + L+A++
Sbjct: 828 LADLTAGYTGADIKTLCNEVGLLALK 905
>00810
Length = 1431
Score = 134 bits (337), Expect = 9e-32, Method: Compositional matrix adjust.
Identities = 93/264 (35%), Positives = 136/264 (51%), Gaps = 10/264 (3%)
Frame = -3
Query: 221 LKEAVVLPMWMPEFFK--GIRRPWKGVLMVGPPGTGKTLLAKAVATECKTTFFNVSSSTL 278
+KE V+LP + F+ + +P KGVL+ GPPG GKT++AKA A F N+ S+L
Sbjct: 1408 VKETVILPFKRADLFRHSSLLQPPKGVLLHGPPGCGKTMIAKATAKAAGARFINLQVSSL 1229
Query: 279 TSKYRGESEKLVRLLFEMARFYSPATIFIDEIDSICSRRGTSEEHEASRRVKAELLVQMD 338
K+ GES+K +F +A P IFIDEIDS R TS +HEA+ +K + + D
Sbjct: 1228 VDKWYGESQKRAEAVFSLAIKLQPTIIFIDEIDSFLRSR-TSTDHEATAMIKTQFMSFWD 1052
Query: 339 GVGGTSENDDPSKMVMVLAATNFPWDIDEALRRRLEKRIYIPLPSAKGXXXXXXXXXXXX 398
G+ DP VMV+ ATN P D+D A+ RR+ +I LP
Sbjct: 1051 GL-----MTDPDCRVMVMGATNRPQDVDAAILRRMPSMFHIGLP-GPAQRRSIFNLILSK 890
Query: 399 XXADDVDLASIAENMEGYSGADITNVCRDASLMAMRRRIE------GLTPEEIRNLSKEE 452
D ++ +AE +G+SG+DI VCR A++ + I+ PE+ R L
Sbjct: 889 ERIDALNYDELAEMTDGFSGSDIREVCRAAAVATVHEFIQEEVVRGDNNPEDDRGLRN-- 716
Query: 453 MHMPTTMEDFEMALKKV--SKSVS 474
TM D ++++ KV +KS+S
Sbjct: 715 ----LTMRDLQLSITKVQQTKSIS 656
>23766
Length = 1463
Score = 129 bits (325), Expect(2) = 7e-31, Method: Compositional matrix adjust.
Identities = 79/198 (39%), Positives = 108/198 (54%), Gaps = 4/198 (2%)
Frame = +1
Query: 243 KGVLMVGPPGTGKTLLAKAVATECKTTFFNVSSSTLTSKYRGESEKLVRLLFEMARFYSP 302
KGV++ GPPGTGKTLLAKAVA + TF V S L KY G+ KLVR LF +A ++P
Sbjct: 157 KGVILYGPPGTGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAP 336
Query: 303 ATIFIDEIDSICSRR--GTSEEHEASRRVKAELLVQMDGVGGTSENDDPSKMVMVLAATN 360
+ +FIDEID++ ++R S +R ELL Q+DG D V V+ ATN
Sbjct: 337 SIVFIDEIDAVGTKRYESNSGGEREIQRTMLELLNQLDGF-------DSRGDVKVIMATN 495
Query: 361 FPWDIDEALRR--RLEKRIYIPLPSAKGXXXXXXXXXXXXXXADDVDLASIAENMEGYSG 418
+D AL R R++++I PLP K A DV++ + + SG
Sbjct: 496 RIETLDPALIRPGRIDRKIEFPLPDEKTKRRIFTIHTSRMTLAGDVNIDDYVMSKDDLSG 675
Query: 419 ADITNVCRDASLMAMRRR 436
ADI +C +A L+A+R R
Sbjct: 676 ADIKAICTEAGLLALRER 729
Score = 22.3 bits (46), Expect(2) = 7e-31, Method: Compositional matrix adjust.
Identities = 13/39 (33%), Positives = 22/39 (56%), Gaps = 2/39 (5%)
Frame = +2
Query: 204 PNVRWDDIADLVEAKKLLKEAVVLPMWMPEFFK--GIRR 240
P + DI L + +KE+V LP+ PE+++ GI+
Sbjct: 38 PQETYADIGGLDTQIQEIKESVELPLTHPEYYEEMGIKH 154
>19129
Length = 1020
Score = 130 bits (327), Expect = 1e-30, Method: Compositional matrix adjust.
Identities = 80/191 (41%), Positives = 115/191 (60%), Gaps = 6/191 (3%)
Frame = +1
Query: 199 IISQNPNVRWDDIADLVEAKKLLKEAVVLPMWMPEFFK--GIRRPWKGVLMVGPPGTGKT 256
++ + P+ ++ + L + K +KE + LP+ PE F+ GI +P KGVL+ GPPGTGKT
Sbjct: 457 MVEKVPDSTYEMVGGLDKQIKEIKEVIELPVKHPELFEALGIAQP-KGVLLYGPPGTGKT 633
Query: 257 LLAKAVATECKTTFFNVSSSTLTSKYRGESEKLVRLLFEMARFYSPATIFIDEIDSICSR 316
LLA+AVA + TF VS S L K+ GE ++VR LF MAR ++P+ IF+DEIDSI S
Sbjct: 634 LLARAVAHHTECTFIRVSGSELVQKFIGEGSRMVRELFVMAREHAPSIIFMDEIDSIGSS 813
Query: 317 R--GTSEEHEASRRVKAELLVQMDGVGGTSENDDPSKMVMVLAATNFPWDIDEALRR--R 372
R G S +R ELL Q+DG +P + + V+ ATN +D AL R R
Sbjct: 814 RLEGGSGGDSEVQRTMLELLNQLDGF-------EPKQNIKVIMATNRIDILDSALLRPGR 972
Query: 373 LEKRIYIPLPS 383
++++I P P+
Sbjct: 973 IDRKIEFPPPN 1005
>07247
Length = 1753
Score = 124 bits (310), Expect = 1e-28, Method: Compositional matrix adjust.
Identities = 77/192 (40%), Positives = 108/192 (56%), Gaps = 5/192 (2%)
Frame = -2
Query: 248 VGPPGTGKTLLAKAVATECKTTFFNVSSSTLTSKYRGESEKLVRLLFEMARFYSPATIFI 307
V PGTGKTLLA+AVA++ F V SS + KY GES +L+R +F AR + P IF+
Sbjct: 1416 VRTPGTGKTLLARAVASQLDCNFLKVVSSAIVDKYIGESARLIREMFAFARDHEPCIIFM 1237
Query: 308 DEIDSICSRR---GTSEEHEASRRVKAELLVQMDGVGGTSENDDPSKMVMVLAATNFPWD 364
DEID+I RR GTS + E R + ELL QMDG + KM+M ATN P
Sbjct: 1236 DEIDAIGGRRFSEGTSADREIQRTL-MELLNQMDGFDALGQ----VKMIM---ATNRPDT 1081
Query: 365 IDEALRR--RLEKRIYIPLPSAKGXXXXXXXXXXXXXXADDVDLASIAENMEGYSGADIT 422
+D AL R RL+++I I LP+ + ++D ++ + E ++GAD+
Sbjct: 1080 LDPALLRPGRLDRKIEISLPNEQARLEILKIHANPIAKHGEIDWEAVVKLSEDFNGADLR 901
Query: 423 NVCRDASLMAMR 434
NVC +A + A+R
Sbjct: 900 NVCTEAGMFAIR 865
>38672
Length = 730
Score = 81.3 bits (199), Expect(2) = 1e-21, Method: Compositional matrix adjust.
Identities = 54/162 (33%), Positives = 82/162 (50%), Gaps = 3/162 (1%)
Frame = -3
Query: 314 CSRRGTSEEH-EASRRVKAELLVQMDGVGGTSENDDPSKMVMVLAATNFPWDIDEALRR- 371
C R E H E RR+ ++LL MDG+ S V+V+AATN P +D ALRR
Sbjct: 629 CHRPKERETHGEVERRIVSQLLTLMDGLKQRSH-------VIVMAATNRPNSVDAALRRF 471
Query: 372 -RLEKRIYIPLPSAKGXXXXXXXXXXXXXXADDVDLASIAENMEGYSGADITNVCRDASL 430
R ++ + I +P A G ADDVDL +A G+ GAD+ +C +A+L
Sbjct: 470 GRFDREVDIGIPDATGRLEILRIHTKNMKLADDVDLEQVASETHGHVGADVAALCSEAAL 291
Query: 431 MAMRRRIEGLTPEEIRNLSKEEMHMPTTMEDFEMALKKVSKS 472
+R +++ + E+ ++ + TM+DF AL K + S
Sbjct: 290 QQIREKMDLIDLEDDTIDAEVLDSLAVTMDDFRWALGKSNPS 165
Score = 40.4 bits (93), Expect(2) = 1e-21, Method: Compositional matrix adjust.
Identities = 20/40 (50%), Positives = 26/40 (65%)
Frame = -1
Query: 278 LTSKYRGESEKLVRLLFEMARFYSPATIFIDEIDSICSRR 317
+ SK GESE +R FE A +PA IFIDE+D+I +R
Sbjct: 730 IMSKLAGESESNLRKAFEEAEKNAPAIIFIDELDAIAPKR 611
Score = 38.1 bits (87), Expect = 0.009, Method: Compositional matrix adjust.
Identities = 22/52 (42%), Positives = 28/52 (53%), Gaps = 1/52 (1%)
Frame = -3
Query: 197 RDIISQNPNVRWDDIADLVEAKKLLKEAVVLPMWMPE-FFKGIRRPWKGVLM 247
R+ + PNV W+D+ L KK L+E V P+ PE F K P KGVL
Sbjct: 158 RETCVEVPNVSWEDVGGLENVKKELQELVQYPVEHPEKFLKFGMTPSKGVLF 3
>12235
Length = 1749
Score = 82.0 bits (201), Expect = 5e-16, Method: Compositional matrix adjust.
Identities = 61/179 (34%), Positives = 86/179 (48%), Gaps = 9/179 (5%)
Frame = +1
Query: 265 ECKTTFFNVSSSTLTSKYRGESEKLVRLLFEMARFYSPATIFIDEIDSICSRR-----GT 319
E F VS S + G VR +F AR +P +F+DEID++ +R G
Sbjct: 1 EANVPFITVSGSEFLEMFVGVGPSRVRDMFATARKNAPCILFVDEIDAVGRKRSGRNFGG 180
Query: 320 SEEHEASRRVKAELLVQMDGVGGTSENDDPSKMVMVLAATNFPWDIDEALRR--RLEKRI 377
E E + +LLV+MDG + V+VLAATN +D AL R R +++I
Sbjct: 181 QSEQENTLN---QLLVEMDGF-------NTQTGVVVLAATNRVDILDAALLRPGRFDRQI 330
Query: 378 YIPLPSAKGXXXXXXXXXX-XXXXADDVDLA-SIAENMEGYSGADITNVCRDASLMAMR 434
++PLP K + DLA +A G+SGADI NVC +A+L+A R
Sbjct: 331 FVPLPDIKXRASIFKVHLDPLKTEVNKNDLARKMAALTPGFSGADIANVCNEAALIAAR 507
>06766
Length = 976
Score = 65.5 bits (158), Expect = 5e-11, Method: Compositional matrix adjust.
Identities = 42/122 (34%), Positives = 59/122 (48%), Gaps = 9/122 (7%)
Frame = +2
Query: 372 RLEKRIYIPLPSAKGXXXXXXXXXXXXXXADDVDLASIAENMEGYSGADITNVCRDASLM 431
RL++ IYIPLP K A +VDL IA+ +G+SGAD+T +C+ A +
Sbjct: 2 RLDQLIYIPLPDDKSREAILKANLRKSPLAKEVDLTYIAKVTQGFSGADLTEICQRACKL 181
Query: 432 AMRRRIEGLTPEEIRNLSKEEMHMPTTMED---------FEMALKKVSKSVSAADIERYE 482
A+R+ IE E + M ED FE A+K +SVS DI +YE
Sbjct: 182 AIRQAIEAEIRREKDRAENQNSAMDMDEEDPVPEITRAHFEEAMKFARRSVSDNDIRKYE 361
Query: 483 KW 484
+
Sbjct: 362 MF 367
>26408
Length = 463
Score = 55.8 bits (133), Expect = 4e-08, Method: Composition-based stats.
Identities = 29/57 (50%), Positives = 38/57 (66%), Gaps = 2/57 (3%)
Frame = +1
Query: 217 AKKLLKEAVVLPMWMPEFFK--GIRRPWKGVLMVGPPGTGKTLLAKAVATECKTTFF 271
A + +KE + LP+ PE F GI +P KGVL+ GPPGTGKTLLA+AVA + +
Sbjct: 286 ANQRIKEVIELPVKHPELFDALGIAQP-KGVLLYGPPGTGKTLLARAVAHHTRVHIY 453
>17843
Length = 772
Score = 53.5 bits (127), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 48/160 (30%), Positives = 75/160 (46%), Gaps = 20/160 (12%)
Frame = +1
Query: 245 VLMVGPPGTGKTLLAKAVATECKT---------TFFNVSSSTLTSKYRGESEKLVRLLFE 295
+L+ GPPGTGKT L KA+A + ++S +L SK+ ES KLV +F+
Sbjct: 193 ILLHGPPGTGKTTLCKALAHKLCIRLSHRFSCGQLVEINSHSLFSKWFSESGKLVTKMFQ 372
Query: 296 MARFYSP-----ATIFIDEIDSICSRRGT----SEEHEASRRVKAELLVQMDGVGGTSEN 346
Y + IDE++S+ + R + +E +A R V A +L Q+D + +
Sbjct: 373 RLHDYMVDPELLVCVLIDEVESLTAARKSCLNGNEPSDAIRVVNA-VLTQIDQLKKFAN- 546
Query: 347 DDPSKMVMVLAATNFPWDIDEALRRRLEKRIYI--PLPSA 384
++L +N ID A R + + YI P P A
Sbjct: 547 ------CLILTTSNITGAIDLAFVDRADIKQYIGPPTPPA 648
>15498
Length = 769
Score = 48.5 bits (114), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 27/93 (29%), Positives = 51/93 (54%), Gaps = 3/93 (3%)
Frame = -1
Query: 209 DDIADLVEAKKLLKEAVVLPMWMPEFFKGIRRPW-KGVLMVGPPGTGKTLLAKAVATECK 267
+ + L + ++L+ E +LP+ P + + P K +L+ GP G+GK +L A+ E
Sbjct: 283 EPMPSLSDVRRLVTEFGILPLGSPSVHE--QAPLTKSILLAGPRGSGKKMLVHALCNEVG 110
Query: 268 TTFFNVSSSTLTSKYRGES--EKLVRLLFEMAR 298
F++S + L KY G+ + L+ L+F++ R
Sbjct: 109 ANLFDLSPANLAGKYPGKDGLKMLMHLIFKVGR 11
>19561
Length = 474
Score = 37.4 bits (85), Expect = 0.014, Method: Compositional matrix adjust.
Identities = 25/78 (32%), Positives = 33/78 (42%), Gaps = 3/78 (3%)
Frame = -1
Query: 238 IRRPWKGV-LMVGPPGTGKTLLAKAVATECKTTF--FNVSSSTLTSKYRGESEKLVRLLF 294
+RP + V L+ GPPG GKT LA VA N S + + E ++
Sbjct: 396 FKRPVQKVALLCGPPGLGKTTLAHIVAKHAGYNVVEMNASDDRSVEVFSNKIEAATQMRA 217
Query: 295 EMARFYSPATIFIDEIDS 312
M P + IDEID
Sbjct: 216 VMGADPRPNCLIIDEIDG 163
>01279
Length = 2183
Score = 35.8 bits (81), Expect = 0.044, Method: Compositional matrix adjust.
Identities = 16/33 (48%), Positives = 21/33 (63%)
Frame = -3
Query: 233 EFFKGIRRPWKGVLMVGPPGTGKTLLAKAVATE 265
E K + + VL+ GPPGTGKT +A A+A E
Sbjct: 1944 ELIKTKKMAGRAVLLAGPPGTGKTAIALAIAQE 1846
>22221
Length = 490
Score = 32.3 bits (72), Expect = 0.45, Method: Composition-based stats.
Identities = 20/56 (35%), Positives = 24/56 (42%), Gaps = 7/56 (12%)
Frame = -3
Query: 91 PASEGEVWSMPV-------PVERRPSPGPRKRQSSQYSDPKSHGNRPSTTVRVHRS 139
PA G W PV P +R P G R Q +DP S + PS + HRS
Sbjct: 434 PACSGHRWRSPVGQPA*PEPKQRSPGHGSRVP**RQRADPCSRSSTPSPKLGAHRS 267
>08000
Length = 343
Score = 30.0 bits (66), Expect = 2.5, Method: Composition-based stats.
Identities = 11/26 (42%), Positives = 17/26 (65%)
Frame = +3
Query: 403 DVDLASIAENMEGYSGADITNVCRDA 428
DVD+ +A+ GY+GADI +C +
Sbjct: 36 DVDVKQLADLTAGYTGADIKTLCNEG 113
>18409
Length = 465
Score = 29.6 bits (65), Expect = 3.0, Method: Composition-based stats.
Identities = 20/67 (29%), Positives = 28/67 (41%)
Frame = +1
Query: 88 HDLPASEGEVWSMPVPVERRPSPGPRKRQSSQYSDPKSHGNRPSTTVRVHRSSAQNVHND 147
H PA VW P P +R P+P D HG+R ++ +R + VH+
Sbjct: 259 HGPPARS--VWLSPRPRQRTPAP----------RDWSCHGHRRRASL*CYRCTCLPVHHQ 402
Query: 148 RGKAVRC 154
G A C
Sbjct: 403 TGVAGTC 423
>27434
Length = 472
Score = 29.3 bits (64), Expect = 3.7, Method: Composition-based stats.
Identities = 11/27 (40%), Positives = 17/27 (62%)
Frame = +2
Query: 248 VGPPGTGKTLLAKAVATECKTTFFNVS 274
VGPPG GKT + +++AT F ++
Sbjct: 179 VGPPGVGKTSIGRSIATTLGREFHRIA 259
>22754
Length = 1013
Score = 28.5 bits (62), Expect = 5.8, Method: Compositional matrix adjust.
Identities = 13/25 (52%), Positives = 17/25 (68%)
Frame = -3
Query: 137 HRSSAQNVHNDRGKAVRCREKKEQN 161
H S A+ HN+RGK RC ++ EQN
Sbjct: 468 HSSHAEK*HNERGKPTRCCDQLEQN 394
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000356381 | hsapiens_gene_ensembl | Katanin p60
ATPase-containing subunit A1 (EC 3.6.4.3) (Katanin p60 subunit A1)
(p60 katanin). [Source:Uniprot/SWISSPROT;Acc:O75449]
(491 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
25671 187 1e-57
20270 157 4e-47
07243 157 6e-39
03022 145 3e-35
01642 140 1e-33
02582 139 2e-33
00810 134 9e-32
23766 129 7e-31
19129 130 1e-30
07247 124 1e-28
38672 81 1e-21
12235 82 5e-16
06766 65 5e-11
26408 56 4e-08
17843 54 2e-07
15498 49 6e-06
19561 37 0.014
01279 36 0.044
22221 32 0.45
08000 30 2.5
18409 30 3.0
27434 29 3.7
22754 28 5.8
>25671
Length = 441
Score = 187 bits (475), Expect(2) = 1e-57, Method: Composition-based stats.
Identities = 92/110 (83%), Positives = 101/110 (91%)
Frame = +2
Query: 253 TGKTLLAKAVATECKTTFFNVSSSTLTSKYRGESEKLVRLLFEMARFYSPATIFIDEIDS 312
TGKT+LAKAVATEC TTFFNVS+S+L +KYRGESEKLVRLLFEMA FY+P+TIFIDEIDS
Sbjct: 2 TGKTMLAKAVATECGTTFFNVSTSSLANKYRGESEKLVRLLFEMAHFYAPSTIFIDEIDS 181
Query: 313 ICSRRGTSEEHEASRRVKAELLVQMDGVGGTSENDDPSKMVMVLAATNFP 362
ICS+RG+ EHEASRRVK+ELLVQMDGVG T NDDPSK VMVLAATNFP
Sbjct: 182 ICSKRGSDSEHEASRRVKSELLVQMDGVGVT--NDDPSKAVMVLAATNFP 325
Score = 54.3 bits (129), Expect(2) = 1e-57, Method: Compositional matrix adjust.
Identities = 24/25 (96%), Positives = 25/25 (100%)
Frame = +3
Query: 362 PWDIDEALRRRLEKRIYIPLPSAKG 386
PWDIDEALRRRLEKRIYIPLPSA+G
Sbjct: 324 PWDIDEALRRRLEKRIYIPLPSAEG 398
>20270
Length = 542
Score = 157 bits (397), Expect(2) = 4e-47, Method: Compositional matrix adjust.
Identities = 78/136 (57%), Positives = 101/136 (74%), Gaps = 1/136 (0%)
Frame = -3
Query: 240 RPWKGVLMVGPPGTGKTLLAKAVATECK-TTFFNVSSSTLTSKYRGESEKLVRLLFEMAR 298
+PW+G+L+ GPPGTGK+ LAKAVATE +TFF+VSSS L SK+ GESEKLV+ LF++AR
Sbjct: 387 KPWRGILLYGPPGTGKSYLAKAVATEANNSTFFSVSSSDLVSKWLGESEKLVKTLFQLAR 208
Query: 299 FYSPATIFIDEIDSICSRRGTSEEHEASRRVKAELLVQMDGVGGTSENDDPSKMVMVLAA 358
P+ IFIDE+D++C R + E E++RR+K E LVQM GVG ND+ V+VL A
Sbjct: 207 ENQPSIIFIDEVDALCGSR-SENESESARRIKTEFLVQMQGVG----NDNTG--VLVLGA 49
Query: 359 TNFPWDIDEALRRRLE 374
TN PW +D A+RRR E
Sbjct: 48 TNIPWTLDSAIRRRFE 1
Score = 49.7 bits (117), Expect(2) = 4e-47, Method: Compositional matrix adjust.
Identities = 23/43 (53%), Positives = 28/43 (65%)
Frame = -1
Query: 197 RDIISQNPNVRWDDIADLVEAKKLLKEAVVLPMWMPEFFKGIR 239
R + + PNVRWDD+A L AK LKEAV+LP+ P F G R
Sbjct: 515 RSHVVEKPNVRWDDVAGLNGAKDALKEAVILPVKFPHLFTGKR 387
>07243
Length = 1112
Score = 157 bits (398), Expect = 6e-39, Method: Compositional matrix adjust.
Identities = 100/251 (39%), Positives = 142/251 (56%), Gaps = 8/251 (3%)
Frame = +1
Query: 192 VEALERDIISQNP-NVRWDDIADLVEAKKLLKEAVVLPMWMPEFF--KGIRRPWKGVLMV 248
V+ L ++ ++P +V + I L E + L+E + LP+ PE F GI P KG L+
Sbjct: 151 VDPLVYNMSHEDPGDVTYSAIGGLTEQIRELREVIELPLLNPELFLRVGIT-PPKGCLLY 327
Query: 249 GPPGTGKTLLAKAVATECKTTFFNVSSSTLTSKYRGESEKLVRLLFEMARFYSPATIFID 308
GPPGTGKTLLA+AVA++ F V SS + KY GES +L+R +F AR + P IF+D
Sbjct: 328 GPPGTGKTLLARAVASQLDANFLKVVSSAIVDKYIGESARLIREMFNYARDHQPCIIFMD 507
Query: 309 EIDSICSRR---GTSEEHEASRRVKAELLVQMDGVGGTSENDDPSKMVMVLAATNFPWDI 365
EID+I RR GTS + E R + ELL QMDG + KM+M ATN P +
Sbjct: 508 EIDAIGGRRFSEGTSADREIQRTL-MELLNQMDGFDSLGQ----VKMIM---ATNRPDTL 663
Query: 366 DEALRR--RLEKRIYIPLPSAKGXXXXXXXXXXXXXXADDVDLASIAENMEGYSGADITN 423
D AL R RL+++I IPLP+ + ++D +I + + ++GAD+ N
Sbjct: 664 DPALLRPGRLDRKIEIPLPNEQARLEILKIHALIIAKHGEIDYEAIVKLSDNFNGADLRN 843
Query: 424 VCRDASLMAMR 434
VC +A L A+R
Sbjct: 844 VCTEAGLFAIR 876
>03022
Length = 2255
Score = 145 bits (366), Expect = 3e-35, Method: Compositional matrix adjust.
Identities = 98/314 (31%), Positives = 159/314 (50%), Gaps = 5/314 (1%)
Frame = +2
Query: 165 EEKNKSPAAVTEPETNKFDSTGYDKDLVEALERDIISQNPNVRWDDIADLVEAKKLLKEA 224
+E++ + A+TE D G K A +R+ + P W+D+ L + LK++
Sbjct: 1310 QEQDIAAVALTEE-----DFMGALKKAQPAAKREGFATVPTTTWEDVGALSNVRAQLKDS 1474
Query: 225 VVLPMWMPEFFKGIRRPWK-GVLMVGPPGTGKTLLAKAVATECKTTFFNVSSSTLTSKYR 283
++ + PE P G+++VGPPG GKTL+AKA+A E F + L KY
Sbjct: 1475 ILCRIHDPEVSSAFGLPTNSGIILVGPPGCGKTLVAKAMANEAGLNFIYIKGPELLDKYV 1654
Query: 284 GESEKLVRLLFEMARFYSPATIFIDEIDSICSRRGTSEEHEASRRVKAELLVQMDGVGGT 343
GESE+ +R F+ A+ +P IF DE+D++CS R ++ + V +LL MDG G
Sbjct: 1655 GESERNLREKFDKAQACAPCLIFFDEMDTLCSNRQNNDGSNVGKSVTNQLLALMDGCGER 1834
Query: 344 SENDDPSKMVMVLAATNFPWDIDEALRR--RLEKRIYIPLPSAKGXX--XXXXXXXXXXX 399
S+ V V+ ATN ++D AL+R R +++I+I LP G
Sbjct: 1835 SQ-------VYVMGATNIIENVDPALQRPGRFDRKIFIGLPDTDGRLDILRALTKGGSQR 1993
Query: 400 XADDVDLASIAENMEGYSGADITNVCRDASLMAMRRRIEGLTPEEIRNLSKEEMHMPTTM 459
+ D+ +A++ EG+SGAD+ ++ +AS +A++ E + + R S E + T
Sbjct: 1994 KLESCDMQQLAQDTEGFSGADLKHLVNEASTIALK---ESMADQAWREDSHREYVV--TG 2158
Query: 460 EDFEMALKKVSKSV 473
+ F AL+ V SV
Sbjct: 2159 DQFTRALQLVKPSV 2200
>01642
Length = 1406
Score = 140 bits (352), Expect = 1e-33, Method: Compositional matrix adjust.
Identities = 90/241 (37%), Positives = 130/241 (53%), Gaps = 6/241 (2%)
Frame = -1
Query: 200 ISQNPNVRWDDIADLVEAKKLLKEAVVLPMWMPEFFKGIR-RPWKGVLMVGPPGTGKTLL 258
+ ++P + DI + K+ ++EAV LP+ E +K I P +GVLM GPPG GKT+L
Sbjct: 1022 LMRSPT*XYSDIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTML 843
Query: 259 AKAVATECKTTFFNVSSSTLTSKYRGESEKLVRLLFEMARFYSPATIFIDEIDSICSRR- 317
AKAVA F V S KY GE ++VR +F +A+ +PA IFIDEID+I ++R
Sbjct: 842 AKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRF 663
Query: 318 --GTSEEHEASRRVKAELLVQMDGVGGTSENDDPSKMVMVLAATNFPWDIDEALRR--RL 373
T + E +R+ ELL QMDG D + V V+ ATN +D AL R RL
Sbjct: 662 DAQTGADREV-QRILLELLNQMDGF-------DQTVNVKVIMATNRADTLDPALLRPGRL 507
Query: 374 EKRIYIPLPSAKGXXXXXXXXXXXXXXADDVDLASIAENMEGYSGADITNVCRDASLMAM 433
+++I PLP + +++VDL + SGADI +C++A + A+
Sbjct: 506 DRKIEFPLPDRRQKRLIFSTITGKMNISEEVDLEDYVARPDKISGADINAICQEAGMQAV 327
Query: 434 R 434
R
Sbjct: 326 R 324
>02582
Length = 1101
Score = 139 bits (351), Expect = 2e-33, Method: Compositional matrix adjust.
Identities = 92/266 (34%), Positives = 141/266 (53%), Gaps = 29/266 (10%)
Frame = +3
Query: 198 DIISQNPNVRWDDIADLVEAKKLLKEAVVLPMWMPEFFKGIRRPW-KGVLMVGPPGTGKT 256
D I +V W DI L K +++AV P+ P+ F+ + P KGVL+ GPPG GKT
Sbjct: 108 DCIVDARSVPWTDIGGLDLVKLQIRQAVEWPLLYPDTFQALGLPLTKGVLLYGPPGCGKT 287
Query: 257 LLAKAVATECKTTFFNVSSSTLTSKYRGESEKLVRLLFEMARFYSPATIFIDEIDSICSR 316
LA+A AT C TF ++S + L S Y G++EK + F+ AR +P+ +F+DE+D+I +
Sbjct: 288 TLAQAAATACHVTFLSLSCAQLYSPYVGDAEKKISETFQKARALAPSILFLDEMDAIVGK 467
Query: 317 RGTSEEHEA-SRRVKAELLVQMDGVG---------------GTSEN----------DDPS 350
R S S RV + LL +MDG+G G+S++ +
Sbjct: 468 RSDSSLGSGVSERVLSALLNEMDGIGVRLDDKSDSREMEIEGSSDHTPQVRQHAVKEAHD 647
Query: 351 KMVMVLAATNFPWDIDEALRR--RLEKRIYIPLPSAKGXXXXXXXXXXXXXXADDVDLAS 408
+ V+V+AATN P +D AL R R+++ IY+P P +G DVD+
Sbjct: 648 RHVLVVAATNRPDMLDPALLRPGRMDRLIYVPPPDVQGRLQSFTIHTRKMPLGKDVDVKQ 827
Query: 409 IAENMEGYSGADITNVCRDASLMAMR 434
+A+ GY+GADI +C + L+A++
Sbjct: 828 LADLTAGYTGADIKTLCNEVGLLALK 905
>00810
Length = 1431
Score = 134 bits (337), Expect = 9e-32, Method: Compositional matrix adjust.
Identities = 93/264 (35%), Positives = 136/264 (51%), Gaps = 10/264 (3%)
Frame = -3
Query: 221 LKEAVVLPMWMPEFFK--GIRRPWKGVLMVGPPGTGKTLLAKAVATECKTTFFNVSSSTL 278
+KE V+LP + F+ + +P KGVL+ GPPG GKT++AKA A F N+ S+L
Sbjct: 1408 VKETVILPFKRADLFRHSSLLQPPKGVLLHGPPGCGKTMIAKATAKAAGARFINLQVSSL 1229
Query: 279 TSKYRGESEKLVRLLFEMARFYSPATIFIDEIDSICSRRGTSEEHEASRRVKAELLVQMD 338
K+ GES+K +F +A P IFIDEIDS R TS +HEA+ +K + + D
Sbjct: 1228 VDKWYGESQKRAEAVFSLAIKLQPTIIFIDEIDSFLRSR-TSTDHEATAMIKTQFMSFWD 1052
Query: 339 GVGGTSENDDPSKMVMVLAATNFPWDIDEALRRRLEKRIYIPLPSAKGXXXXXXXXXXXX 398
G+ DP VMV+ ATN P D+D A+ RR+ +I LP
Sbjct: 1051 GL-----MTDPDCRVMVMGATNRPQDVDAAILRRMPSMFHIGLP-GPAQRRSIFNLILSK 890
Query: 399 XXADDVDLASIAENMEGYSGADITNVCRDASLMAMRRRIE------GLTPEEIRNLSKEE 452
D ++ +AE +G+SG+DI VCR A++ + I+ PE+ R L
Sbjct: 889 ERIDALNYDELAEMTDGFSGSDIREVCRAAAVATVHEFIQEEVVRGDNNPEDDRGLRN-- 716
Query: 453 MHMPTTMEDFEMALKKV--SKSVS 474
TM D ++++ KV +KS+S
Sbjct: 715 ----LTMRDLQLSITKVQQTKSIS 656
>23766
Length = 1463
Score = 129 bits (325), Expect(2) = 7e-31, Method: Compositional matrix adjust.
Identities = 79/198 (39%), Positives = 108/198 (54%), Gaps = 4/198 (2%)
Frame = +1
Query: 243 KGVLMVGPPGTGKTLLAKAVATECKTTFFNVSSSTLTSKYRGESEKLVRLLFEMARFYSP 302
KGV++ GPPGTGKTLLAKAVA + TF V S L KY G+ KLVR LF +A ++P
Sbjct: 157 KGVILYGPPGTGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAP 336
Query: 303 ATIFIDEIDSICSRR--GTSEEHEASRRVKAELLVQMDGVGGTSENDDPSKMVMVLAATN 360
+ +FIDEID++ ++R S +R ELL Q+DG D V V+ ATN
Sbjct: 337 SIVFIDEIDAVGTKRYESNSGGEREIQRTMLELLNQLDGF-------DSRGDVKVIMATN 495
Query: 361 FPWDIDEALRR--RLEKRIYIPLPSAKGXXXXXXXXXXXXXXADDVDLASIAENMEGYSG 418
+D AL R R++++I PLP K A DV++ + + SG
Sbjct: 496 RIETLDPALIRPGRIDRKIEFPLPDEKTKRRIFTIHTSRMTLAGDVNIDDYVMSKDDLSG 675
Query: 419 ADITNVCRDASLMAMRRR 436
ADI +C +A L+A+R R
Sbjct: 676 ADIKAICTEAGLLALRER 729
Score = 22.3 bits (46), Expect(2) = 7e-31, Method: Compositional matrix adjust.
Identities = 13/39 (33%), Positives = 22/39 (56%), Gaps = 2/39 (5%)
Frame = +2
Query: 204 PNVRWDDIADLVEAKKLLKEAVVLPMWMPEFFK--GIRR 240
P + DI L + +KE+V LP+ PE+++ GI+
Sbjct: 38 PQETYADIGGLDTQIQEIKESVELPLTHPEYYEEMGIKH 154
>19129
Length = 1020
Score = 130 bits (327), Expect = 1e-30, Method: Compositional matrix adjust.
Identities = 80/191 (41%), Positives = 115/191 (60%), Gaps = 6/191 (3%)
Frame = +1
Query: 199 IISQNPNVRWDDIADLVEAKKLLKEAVVLPMWMPEFFK--GIRRPWKGVLMVGPPGTGKT 256
++ + P+ ++ + L + K +KE + LP+ PE F+ GI +P KGVL+ GPPGTGKT
Sbjct: 457 MVEKVPDSTYEMVGGLDKQIKEIKEVIELPVKHPELFEALGIAQP-KGVLLYGPPGTGKT 633
Query: 257 LLAKAVATECKTTFFNVSSSTLTSKYRGESEKLVRLLFEMARFYSPATIFIDEIDSICSR 316
LLA+AVA + TF VS S L K+ GE ++VR LF MAR ++P+ IF+DEIDSI S
Sbjct: 634 LLARAVAHHTECTFIRVSGSELVQKFIGEGSRMVRELFVMAREHAPSIIFMDEIDSIGSS 813
Query: 317 R--GTSEEHEASRRVKAELLVQMDGVGGTSENDDPSKMVMVLAATNFPWDIDEALRR--R 372
R G S +R ELL Q+DG +P + + V+ ATN +D AL R R
Sbjct: 814 RLEGGSGGDSEVQRTMLELLNQLDGF-------EPKQNIKVIMATNRIDILDSALLRPGR 972
Query: 373 LEKRIYIPLPS 383
++++I P P+
Sbjct: 973 IDRKIEFPPPN 1005
>07247
Length = 1753
Score = 124 bits (310), Expect = 1e-28, Method: Compositional matrix adjust.
Identities = 77/192 (40%), Positives = 108/192 (56%), Gaps = 5/192 (2%)
Frame = -2
Query: 248 VGPPGTGKTLLAKAVATECKTTFFNVSSSTLTSKYRGESEKLVRLLFEMARFYSPATIFI 307
V PGTGKTLLA+AVA++ F V SS + KY GES +L+R +F AR + P IF+
Sbjct: 1416 VRTPGTGKTLLARAVASQLDCNFLKVVSSAIVDKYIGESARLIREMFAFARDHEPCIIFM 1237
Query: 308 DEIDSICSRR---GTSEEHEASRRVKAELLVQMDGVGGTSENDDPSKMVMVLAATNFPWD 364
DEID+I RR GTS + E R + ELL QMDG + KM+M ATN P
Sbjct: 1236 DEIDAIGGRRFSEGTSADREIQRTL-MELLNQMDGFDALGQ----VKMIM---ATNRPDT 1081
Query: 365 IDEALRR--RLEKRIYIPLPSAKGXXXXXXXXXXXXXXADDVDLASIAENMEGYSGADIT 422
+D AL R RL+++I I LP+ + ++D ++ + E ++GAD+
Sbjct: 1080 LDPALLRPGRLDRKIEISLPNEQARLEILKIHANPIAKHGEIDWEAVVKLSEDFNGADLR 901
Query: 423 NVCRDASLMAMR 434
NVC +A + A+R
Sbjct: 900 NVCTEAGMFAIR 865
>38672
Length = 730
Score = 81.3 bits (199), Expect(2) = 1e-21, Method: Compositional matrix adjust.
Identities = 54/162 (33%), Positives = 82/162 (50%), Gaps = 3/162 (1%)
Frame = -3
Query: 314 CSRRGTSEEH-EASRRVKAELLVQMDGVGGTSENDDPSKMVMVLAATNFPWDIDEALRR- 371
C R E H E RR+ ++LL MDG+ S V+V+AATN P +D ALRR
Sbjct: 629 CHRPKERETHGEVERRIVSQLLTLMDGLKQRSH-------VIVMAATNRPNSVDAALRRF 471
Query: 372 -RLEKRIYIPLPSAKGXXXXXXXXXXXXXXADDVDLASIAENMEGYSGADITNVCRDASL 430
R ++ + I +P A G ADDVDL +A G+ GAD+ +C +A+L
Sbjct: 470 GRFDREVDIGIPDATGRLEILRIHTKNMKLADDVDLEQVASETHGHVGADVAALCSEAAL 291
Query: 431 MAMRRRIEGLTPEEIRNLSKEEMHMPTTMEDFEMALKKVSKS 472
+R +++ + E+ ++ + TM+DF AL K + S
Sbjct: 290 QQIREKMDLIDLEDDTIDAEVLDSLAVTMDDFRWALGKSNPS 165
Score = 40.4 bits (93), Expect(2) = 1e-21, Method: Compositional matrix adjust.
Identities = 20/40 (50%), Positives = 26/40 (65%)
Frame = -1
Query: 278 LTSKYRGESEKLVRLLFEMARFYSPATIFIDEIDSICSRR 317
+ SK GESE +R FE A +PA IFIDE+D+I +R
Sbjct: 730 IMSKLAGESESNLRKAFEEAEKNAPAIIFIDELDAIAPKR 611
Score = 38.1 bits (87), Expect = 0.009, Method: Compositional matrix adjust.
Identities = 22/52 (42%), Positives = 28/52 (53%), Gaps = 1/52 (1%)
Frame = -3
Query: 197 RDIISQNPNVRWDDIADLVEAKKLLKEAVVLPMWMPE-FFKGIRRPWKGVLM 247
R+ + PNV W+D+ L KK L+E V P+ PE F K P KGVL
Sbjct: 158 RETCVEVPNVSWEDVGGLENVKKELQELVQYPVEHPEKFLKFGMTPSKGVLF 3
>12235
Length = 1749
Score = 82.0 bits (201), Expect = 5e-16, Method: Compositional matrix adjust.
Identities = 61/179 (34%), Positives = 86/179 (48%), Gaps = 9/179 (5%)
Frame = +1
Query: 265 ECKTTFFNVSSSTLTSKYRGESEKLVRLLFEMARFYSPATIFIDEIDSICSRR-----GT 319
E F VS S + G VR +F AR +P +F+DEID++ +R G
Sbjct: 1 EANVPFITVSGSEFLEMFVGVGPSRVRDMFATARKNAPCILFVDEIDAVGRKRSGRNFGG 180
Query: 320 SEEHEASRRVKAELLVQMDGVGGTSENDDPSKMVMVLAATNFPWDIDEALRR--RLEKRI 377
E E + +LLV+MDG + V+VLAATN +D AL R R +++I
Sbjct: 181 QSEQENTLN---QLLVEMDGF-------NTQTGVVVLAATNRVDILDAALLRPGRFDRQI 330
Query: 378 YIPLPSAKGXXXXXXXXXX-XXXXADDVDLA-SIAENMEGYSGADITNVCRDASLMAMR 434
++PLP K + DLA +A G+SGADI NVC +A+L+A R
Sbjct: 331 FVPLPDIKXRASIFKVHLDPLKTEVNKNDLARKMAALTPGFSGADIANVCNEAALIAAR 507
>06766
Length = 976
Score = 65.5 bits (158), Expect = 5e-11, Method: Compositional matrix adjust.
Identities = 42/122 (34%), Positives = 59/122 (48%), Gaps = 9/122 (7%)
Frame = +2
Query: 372 RLEKRIYIPLPSAKGXXXXXXXXXXXXXXADDVDLASIAENMEGYSGADITNVCRDASLM 431
RL++ IYIPLP K A +VDL IA+ +G+SGAD+T +C+ A +
Sbjct: 2 RLDQLIYIPLPDDKSREAILKANLRKSPLAKEVDLTYIAKVTQGFSGADLTEICQRACKL 181
Query: 432 AMRRRIEGLTPEEIRNLSKEEMHMPTTMED---------FEMALKKVSKSVSAADIERYE 482
A+R+ IE E + M ED FE A+K +SVS DI +YE
Sbjct: 182 AIRQAIEAEIRREKDRAENQNSAMDMDEEDPVPEITRAHFEEAMKFARRSVSDNDIRKYE 361
Query: 483 KW 484
+
Sbjct: 362 MF 367
>26408
Length = 463
Score = 55.8 bits (133), Expect = 4e-08, Method: Composition-based stats.
Identities = 29/57 (50%), Positives = 38/57 (66%), Gaps = 2/57 (3%)
Frame = +1
Query: 217 AKKLLKEAVVLPMWMPEFFK--GIRRPWKGVLMVGPPGTGKTLLAKAVATECKTTFF 271
A + +KE + LP+ PE F GI +P KGVL+ GPPGTGKTLLA+AVA + +
Sbjct: 286 ANQRIKEVIELPVKHPELFDALGIAQP-KGVLLYGPPGTGKTLLARAVAHHTRVHIY 453
>17843
Length = 772
Score = 53.5 bits (127), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 48/160 (30%), Positives = 75/160 (46%), Gaps = 20/160 (12%)
Frame = +1
Query: 245 VLMVGPPGTGKTLLAKAVATECKT---------TFFNVSSSTLTSKYRGESEKLVRLLFE 295
+L+ GPPGTGKT L KA+A + ++S +L SK+ ES KLV +F+
Sbjct: 193 ILLHGPPGTGKTTLCKALAHKLCIRLSHRFSCGQLVEINSHSLFSKWFSESGKLVTKMFQ 372
Query: 296 MARFYSP-----ATIFIDEIDSICSRRGT----SEEHEASRRVKAELLVQMDGVGGTSEN 346
Y + IDE++S+ + R + +E +A R V A +L Q+D + +
Sbjct: 373 RLHDYMVDPELLVCVLIDEVESLTAARKSCLNGNEPSDAIRVVNA-VLTQIDQLKKFAN- 546
Query: 347 DDPSKMVMVLAATNFPWDIDEALRRRLEKRIYI--PLPSA 384
++L +N ID A R + + YI P P A
Sbjct: 547 ------CLILTTSNITGAIDLAFVDRADIKQYIGPPTPPA 648
>15498
Length = 769
Score = 48.5 bits (114), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 27/93 (29%), Positives = 51/93 (54%), Gaps = 3/93 (3%)
Frame = -1
Query: 209 DDIADLVEAKKLLKEAVVLPMWMPEFFKGIRRPW-KGVLMVGPPGTGKTLLAKAVATECK 267
+ + L + ++L+ E +LP+ P + + P K +L+ GP G+GK +L A+ E
Sbjct: 283 EPMPSLSDVRRLVTEFGILPLGSPSVHE--QAPLTKSILLAGPRGSGKKMLVHALCNEVG 110
Query: 268 TTFFNVSSSTLTSKYRGES--EKLVRLLFEMAR 298
F++S + L KY G+ + L+ L+F++ R
Sbjct: 109 ANLFDLSPANLAGKYPGKDGLKMLMHLIFKVGR 11
>19561
Length = 474
Score = 37.4 bits (85), Expect = 0.014, Method: Compositional matrix adjust.
Identities = 25/78 (32%), Positives = 33/78 (42%), Gaps = 3/78 (3%)
Frame = -1
Query: 238 IRRPWKGV-LMVGPPGTGKTLLAKAVATECKTTF--FNVSSSTLTSKYRGESEKLVRLLF 294
+RP + V L+ GPPG GKT LA VA N S + + E ++
Sbjct: 396 FKRPVQKVALLCGPPGLGKTTLAHIVAKHAGYNVVEMNASDDRSVEVFSNKIEAATQMRA 217
Query: 295 EMARFYSPATIFIDEIDS 312
M P + IDEID
Sbjct: 216 VMGADPRPNCLIIDEIDG 163
>01279
Length = 2183
Score = 35.8 bits (81), Expect = 0.044, Method: Compositional matrix adjust.
Identities = 16/33 (48%), Positives = 21/33 (63%)
Frame = -3
Query: 233 EFFKGIRRPWKGVLMVGPPGTGKTLLAKAVATE 265
E K + + VL+ GPPGTGKT +A A+A E
Sbjct: 1944 ELIKTKKMAGRAVLLAGPPGTGKTAIALAIAQE 1846
>22221
Length = 490
Score = 32.3 bits (72), Expect = 0.45, Method: Composition-based stats.
Identities = 20/56 (35%), Positives = 24/56 (42%), Gaps = 7/56 (12%)
Frame = -3
Query: 91 PASEGEVWSMPV-------PVERRPSPGPRKRQSSQYSDPKSHGNRPSTTVRVHRS 139
PA G W PV P +R P G R Q +DP S + PS + HRS
Sbjct: 434 PACSGHRWRSPVGQPA*PEPKQRSPGHGSRVP**RQRADPCSRSSTPSPKLGAHRS 267
>08000
Length = 343
Score = 30.0 bits (66), Expect = 2.5, Method: Composition-based stats.
Identities = 11/26 (42%), Positives = 17/26 (65%)
Frame = +3
Query: 403 DVDLASIAENMEGYSGADITNVCRDA 428
DVD+ +A+ GY+GADI +C +
Sbjct: 36 DVDVKQLADLTAGYTGADIKTLCNEG 113
>18409
Length = 465
Score = 29.6 bits (65), Expect = 3.0, Method: Composition-based stats.
Identities = 20/67 (29%), Positives = 28/67 (41%)
Frame = +1
Query: 88 HDLPASEGEVWSMPVPVERRPSPGPRKRQSSQYSDPKSHGNRPSTTVRVHRSSAQNVHND 147
H PA VW P P +R P+P D HG+R ++ +R + VH+
Sbjct: 259 HGPPARS--VWLSPRPRQRTPAP----------RDWSCHGHRRRASL*CYRCTCLPVHHQ 402
Query: 148 RGKAVRC 154
G A C
Sbjct: 403 TGVAGTC 423
>27434
Length = 472
Score = 29.3 bits (64), Expect = 3.7, Method: Composition-based stats.
Identities = 11/27 (40%), Positives = 17/27 (62%)
Frame = +2
Query: 248 VGPPGTGKTLLAKAVATECKTTFFNVS 274
VGPPG GKT + +++AT F ++
Sbjct: 179 VGPPGVGKTSIGRSIATTLGREFHRIA 259
>22754
Length = 1013
Score = 28.5 bits (62), Expect = 5.8, Method: Compositional matrix adjust.
Identities = 13/25 (52%), Positives = 17/25 (68%)
Frame = -3
Query: 137 HRSSAQNVHNDRGKAVRCREKKEQN 161
H S A+ HN+RGK RC ++ EQN
Sbjct: 468 HSSHAEK*HNERGKPTRCCDQLEQN 394
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000378644 | hsapiens_gene_ensembl | Focal adhesion
kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK) (Protein- tyrosine kinase
2). [Source:Uniprot/SWISSPROT;Acc:Q05397]
(1006 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
06405 221 1e-57
21808 199 4e-51
11780 121 2e-44
09007 176 6e-44
04852 162 7e-40
14116 147 3e-35
07291 137 1e-32
17300 124 5e-30
20640 125 9e-29
07940 119 8e-27
08294 117 2e-26
18996 110 2e-24
14477 108 9e-24
17253 96 6e-20
18921 96 8e-20
22005 96 8e-20
17637 90 5e-18
13305 87 2e-17
00300 87 4e-17
01718 87 4e-17
19301 83 6e-16
12721 77 2e-14
14420 75 2e-13
13592 73 5e-13
27546 69 7e-12
30755 69 1e-11
00715 67 2e-11
13066 67 4e-11
31885 67 4e-11
07833 66 8e-11
09606 65 1e-10
14126 64 2e-10
01060 63 7e-10
19094 62 1e-09
13212 61 2e-09
29581 60 5e-09
19761 59 9e-09
01756 59 1e-08
04591 58 2e-08
03240 57 4e-08
21079 57 5e-08
01707 56 8e-08
18484 55 1e-07
07836 54 2e-07
01966 54 4e-07
26711 51 2e-06
15910 51 2e-06
25550 49 9e-06
12672 49 9e-06
32264 49 1e-05
21433 48 2e-05
28157 47 5e-05
26560 44 3e-04
04138 44 4e-04
01392 42 0.001
12786 42 0.002
07933 40 0.005
03508 40 0.005
37602 39 0.014
38046 38 0.017
11185 37 0.032
18481 37 0.033
02638 37 0.056
00486 35 0.19
26009 35 0.20
16708 34 0.28
15741 34 0.34
27287 34 0.35
27405 34 0.38
21210 33 0.74
25019 32 1.8
32359 30 3.8
>06405
Length = 1965
Score = 221 bits (562), Expect = 1e-57, Method: Compositional matrix adjust.
Identities = 109/275 (39%), Positives = 165/275 (60%), Gaps = 2/275 (0%)
Frame = +1
Query: 410 PSTRDYEIQRERIELGRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFL 469
P +EI+R I + +G GQ+GDV++ ++ VA+KT K T FL
Sbjct: 229 PEPDRWEIERTEIAMKHRLGGGQYGDVYEAMWKRYNK---IVAVKTLKEDTM--ALNDFL 393
Query: 470 QEALTMRQFDHPHIVKLIGVIT-ENPVWIIMELCTLGELRSFLQVRKYSLDLASLILY-A 527
+EA M++ HP++V+L+GV T E P +I+ E G L +L+ + + ++Y A
Sbjct: 394 EEAAIMKEMKHPNLVQLLGVCTREPPFYIVTEFMPHGNLLDYLRSSTREENGPTALMYMA 573
Query: 528 YQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIK 587
Q+++ +AYLE+K F+HRD+AARN LV+ ++ VK+ DFGL+R M+D TY K PIK
Sbjct: 574 TQIASGMAYLETKNFIHRDLAARNCLVADSNMVKVADFGLARLMKDDTYTAHIGAKFPIK 753
Query: 588 WMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNC 647
W APE + F RF++ SD+W FGV +WE+ +G+ P+ GV+ +V +E G R+ PP
Sbjct: 754 WTAPEGLAFNRFSTRSDIWAFGVLLWELATYGMSPYPGVELTEVYHLLERGYRMERPPGT 933
Query: 648 PPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEE 682
P +Y LM KCW +DP RP F E+ L + E+
Sbjct: 934 PADVYILMLKCWQWDPKDRPTFKEIHFLLENMFEK 1038
>21808
Length = 1011
Score = 199 bits (507), Expect = 4e-51, Method: Compositional matrix adjust.
Identities = 98/236 (41%), Positives = 144/236 (61%), Gaps = 1/236 (0%)
Frame = +1
Query: 446 NPALAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITEN-PVWIIMELCTL 504
N VAIKT K+ T D + FL EA M++ HP +++L V T++ P++II EL
Sbjct: 13 NNTTPVAIKTLKSGTMDP--KDFLAEAQIMKKLRHPKLIQLYAVCTQDDPIFIITELMKN 186
Query: 505 GELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGD 564
G L FLQ + L L +LI Q++ +AYLES+ ++HRD+AARN+LVS N+ VK+ D
Sbjct: 187 GSLLEFLQGKGRVLKLPALIDIGAQIACGMAYLESQNYIHRDLAARNILVSDNNTVKIAD 366
Query: 565 FGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQ 624
FGL+R +++ Y + PIKW APE+ N+ RFT SDVW FG+ + E + +G P+
Sbjct: 367 FGLARVIKEDEYEARVGARFPIKWTAPEAANYNRFTIKSDVWSFGILLTETVTYGRVPYP 546
Query: 625 GVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTIL 680
G+ N +V+ ++E+G R+P PP CP LY +M +CW + RP + IL
Sbjct: 547 GMTNAEVLHQVEHGYRMPCPPGCPKPLYDIMLECWRKEEMERPHLRNPAMEAGGIL 714
>11780
Length = 1713
Score = 121 bits (303), Expect(2) = 2e-44, Method: Compositional matrix adjust.
Identities = 69/179 (38%), Positives = 102/179 (56%), Gaps = 1/179 (0%)
Frame = +3
Query: 417 IQRERIELGRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTMR 476
I + +E+G IG+G FGDV++G+Y VAIK K+ D + FLQEA M
Sbjct: 588 IAXQDLEIGEAIGKGDFGDVYKGMYRGQ-----PVAIKQLKD--KDRGEQSFLQEASVMT 746
Query: 477 QFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVRKYS-LDLASLILYAYQLSTALA 535
H ++V+LIGV+ ++++ E G L +L+ R S + I +A A+
Sbjct: 747 SLRHDNLVRLIGVVLGETIFLVTEFMGKGNLVEYLRSRGRSVITKKDQINFATDTCAAME 926
Query: 536 YLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESI 594
YLESKR VHRD+AARNVLV + K+ DFGL+++ + + + K PIKW APE++
Sbjct: 927 YLESKRLVHRDLAARNVLVHDDGKAKVSDFGLAKFGD----FSQTSVKFPIKWTAPEAL 1091
Score = 77.8 bits (190), Expect(2) = 2e-44, Method: Compositional matrix adjust.
Identities = 33/81 (40%), Positives = 49/81 (60%)
Frame = +1
Query: 598 RFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTK 657
+FTS SD+W FG+ +WEI G P+ + DV+ +E G R+ P CPP +YS+M +
Sbjct: 1102 KFTSKSDMWSFGILLWEIYSFGRVPYPRIPLTDVVMHVERGYRMEAPEGCPPEIYSIMKQ 1281
Query: 658 CWAYDPSRRPRFTELKAQLST 678
W DP+ RP F + A+L+
Sbjct: 1282 AWELDPNERPTFKSVLARLNN 1344
>09007
Length = 1440
Score = 176 bits (445), Expect = 6e-44, Method: Compositional matrix adjust.
Identities = 94/274 (34%), Positives = 146/274 (53%), Gaps = 11/274 (4%)
Frame = -1
Query: 417 IQRERIELGRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTMR 476
I ++ + L + +G+G FG V Q I+ + + VA+K ++FL+E M+
Sbjct: 888 ISKDCVALSKSLGQGHFGTVRQAIWTAESGEKVQVAVKCLSKDKIHKDGQEFLKETAIMQ 709
Query: 477 QFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVRK-----YSLDLASLILYAYQLS 531
DH +IV++ GV+ +N IM + L +RS L+ K + L ++ Q+
Sbjct: 708 MLDHENIVRVYGVVMDNGA-DIMLVTELAPMRSLLECVKEVSARVDFSVPRLCDFSQQVC 532
Query: 532 TALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKL----PIK 587
++YLESKR VHRD+AARN+L+ S VK+ D G+S + Y S+ + +
Sbjct: 531 DGMSYLESKRLVHRDLAARNILLFSKSKVKISDVGVSGALGAGKEYYQSQQTIHLQNAVA 352
Query: 588 WMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIE--NGERLPMPP 645
W APES F+SASDVW FGV +WE HG +P+ G+ ++ ++ +RL P
Sbjct: 351 WCAPESFRNLCFSSASDVWAFGVLLWEFFTHGFQPWAGLNGQQIMEAVDAPQSQRLEQPD 172
Query: 646 NCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTI 679
CP Y++M KCW +P RRP F++L L I
Sbjct: 171 LCPKEYYAVMLKCWEQEPQRRPTFSQLFLTLPQI 70
>04852
Length = 1462
Score = 162 bits (410), Expect = 7e-40, Method: Compositional matrix adjust.
Identities = 88/263 (33%), Positives = 141/263 (53%), Gaps = 30/263 (11%)
Frame = +1
Query: 448 ALAVAIKTCKNCTSDSVREKFLQEALTMRQF----DHPHIVKLIGVITEN-PVWIIMELC 502
A VA+K ++ + + F+QE M+ H +IV +G T+ P+W+I+E
Sbjct: 19 ASTVAVKMLRDIVTAVEEQDFVQELQVMKAVKKMGSHINIVNFLGCCTQGGPLWVIVEFA 198
Query: 503 TLGELRSFLQ-----VRKYS-------------------LDLASLILYAYQLSTALAYLE 538
G LR FL+ + Y + +L+ YA+Q++ + +L
Sbjct: 199 KNGNLRDFLESCRDGINGYGKFVSPQDPGWYTKTPGGHVIRRKNLLSYAFQIARGMEFLA 378
Query: 539 SKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRR 598
S++ +HRD+AARNVLV+ +K+ DFGLSR Y K S G+LP+KWMAPE++ R
Sbjct: 379 SRKCIHRDLAARNVLVTEEHVLKIADFGLSR--TGDYYKKRSGGRLPVKWMAPEALFDMR 552
Query: 599 FTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGR-IENGERLPMPPNCPPTLYSLMTK 657
+T+ SDVW FGV +WEI G P+ + N ++ + +++ R+P P LY++M +
Sbjct: 553 YTTKSDVWSFGVVLWEIFSLGGMPYASIPNEELYSKLLDDAYRMPRPELASGNLYAIMER 732
Query: 658 CWAYDPSRRPRFTELKAQLSTIL 680
CW PS RP F++L + +L
Sbjct: 733 CWLNRPSDRPEFSQLVGHIDRLL 801
>14116
Length = 1017
Score = 147 bits (370), Expect = 3e-35, Method: Compositional matrix adjust.
Identities = 85/259 (32%), Positives = 140/259 (54%), Gaps = 19/259 (7%)
Frame = -1
Query: 380 EKQGMRTHAVSVSETDDYAEIID------------EEDTYTMPSTRDYEIQRERIELGRC 427
+ G RT+ + E +DY +D +ED + I RE + +G
Sbjct: 789 DSNGTRTYNLEARE-NDYFNRLDVQGAEAMPLLHIDEDMMKLIENESLLIDREFLTMGEE 613
Query: 428 IGEGQFGDVHQGIYMSPENPA-LAVAIKTCKNCTSDSVR-EKFLQEALTMRQFDHPHIVK 485
IG+G FG V +G PE + VA+KT N + + FLQEAL M+ F H +++
Sbjct: 612 IGKGNFGCVKRGFLTLPEQKGDILVAVKTLHNNNPREIELQSFLQEALIMKDFHHSNVLT 433
Query: 486 LIGV---ITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRF 542
LIG+ + + P+ +++ G+L ++++ ++ + LI+Y ++ + YL +F
Sbjct: 432 LIGICLNLDDMPL-VVLPFMKHGDLLTYIRDDQHQPTIKDLIMYGVDIARGMDYLAGLKF 256
Query: 543 VHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKA--SKGKLPIKWMAPESINFRRFT 600
VHRD+AARN ++ + VK+ DFGL+R + + YY + K KLP+KWMA ES+ +
Sbjct: 255 VHRDLAARNCMLDEDFHVKVADFGLARDIYEKEYYSSENKKAKLPVKWMALESLEKGNYD 76
Query: 601 SASDVWMFGVCMWEILMHG 619
S +DVW +GV +WE+L G
Sbjct: 75 SKTDVWSYGVVLWELLTRG 19
>07291
Length = 833
Score = 137 bits (346), Expect = 1e-32, Method: Compositional matrix adjust.
Identities = 62/164 (37%), Positives = 101/164 (61%), Gaps = 2/164 (1%)
Frame = +1
Query: 518 LDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYY 577
L + L+ + Q++ +AYL+ + VHR++AARN +V+ + ++L D+G++ + +YY
Sbjct: 40 LTVVQLLDFGRQIADGMAYLQEVKVVHRNLAARNCIVTEDGRLQLSDYGVTGSLFPQSYY 219
Query: 578 KA--SKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRI 635
A S + +KWMAPE+I+ F+S SDVW FGV +WE+L G+ P+ V+N+ ++ +
Sbjct: 220 TADDSPARDLVKWMAPETIDNFHFSSKSDVWAFGVVLWELLTRGITPYPDVENSSLLPYL 399
Query: 636 ENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTI 679
+ G R+ P P +Y +MT CW P +RP F EL QL T
Sbjct: 400 KEGHRMKKPKQSPEPVYEMMTACWNESPEQRPDFAELNDQLKTF 531
>17300
Length = 480
Score = 124 bits (310), Expect(2) = 5e-30, Method: Compositional matrix adjust.
Identities = 56/117 (47%), Positives = 78/117 (66%), Gaps = 3/117 (2%)
Frame = +1
Query: 530 LSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDST---YYKASKGKLPI 586
+S+ + L +VHRD+AARN+LV+ K+ DFGLSR +E T Y GK+P+
Sbjct: 1 ISSGMGXLADMGYVHRDLAARNILVNEILVCKVADFGLSREIESDTTEGAYTTKGGKIPV 180
Query: 587 KWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPM 643
+W APE+I +R+FTSASDVW FGV MWE++ +G +P+ N DVI +E G RLP+
Sbjct: 181 RWTAPEAIAYRKFTSASDVWSFGVVMWEVMSYGERPYWNWSNQDVIKAVEKGYRLPL 351
Score = 26.6 bits (57), Expect(2) = 5e-30, Method: Compositional matrix adjust.
Identities = 10/35 (28%), Positives = 18/35 (51%)
Frame = +2
Query: 646 NCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTIL 680
+CP L+ LM W + S RP+ + + L ++
Sbjct: 356 DCPEALHQLMLDAWQKERSHRPKMSMVVKTLDKLI 460
>20640
Length = 1492
Score = 125 bits (314), Expect = 9e-29, Method: Compositional matrix adjust.
Identities = 55/139 (39%), Positives = 85/139 (61%), Gaps = 1/139 (0%)
Frame = +1
Query: 542 FVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASK-GKLPIKWMAPESINFRRFT 600
+VHRD+A RN LV + VK+ DFGL+R + YY+ S+ +PI+WM E+I + +F+
Sbjct: 7 YVHRDLATRNCLVGHDLVVKISDFGLARSVHSVDYYRGSEHDAIPIRWMPLEAILYNKFS 186
Query: 601 SASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWA 660
+ SDVW FGV +WEI ++P+ G+ + +V+ ++ G+ L P PP +Y LM +CW
Sbjct: 187 TQSDVWSFGVVLWEIFAFALQPYYGLTHEEVVRFVKEGKVLACPERTPPPMYELMKQCWH 366
Query: 661 YDPSRRPRFTELKAQLSTI 679
P+ RP F L L +
Sbjct: 367 RRPATRPSFHTLHKTLENM 423
>07940
Length = 1336
Score = 119 bits (297), Expect = 8e-27, Method: Compositional matrix adjust.
Identities = 54/111 (48%), Positives = 77/111 (69%), Gaps = 1/111 (0%)
Frame = -3
Query: 523 LILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYY-KASK 581
LI YAYQ++ + YL SK+ +HRD+AARNVLV+ +K+ DFGL+R ++ YY K +
Sbjct: 341 LISYAYQVARGMEYLASKQCIHRDLAARNVLVAEEYVLKIADFGLTRNLQQFDYYRKTTD 162
Query: 582 GKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVI 632
G+LP+KWMAPE++ R++TS SDVW +GV +WEI G P+ V D+
Sbjct: 161 GRLPVKWMAPEALFDRKYTSKSDVWSYGVLLWEIFTLGGNPYPSVPVEDLF 9
Score = 58.2 bits (139), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 37/114 (32%), Positives = 59/114 (51%), Gaps = 4/114 (3%)
Frame = -3
Query: 403 EEDTYTMPSTRDYEIQRERIELGRCIGEGQFGDVHQGIYMS--PENPALAVAIKTCKNCT 460
E Y +P +E RER+ LG +GEG FG V +G M +N ++ VA+K K
Sbjct: 893 EVSEYDLPLDAKWEFPRERLVLGDRLGEGAFGLVMKGEAMGIFKDNNSVTVAVKMLKEDA 714
Query: 461 SDSVREKFLQEALTMRQFD-HPHIVKLIGVITE-NPVWIIMELCTLGELRSFLQ 512
+D ++E M+ H +I+ L+G T+ +++I+E G LR FL+
Sbjct: 713 TDREMMDLIREMEMMKVIGKHKNIINLLGCCTQRGALYVIVEFAPHGNLRDFLK 552
>08294
Length = 1849
Score = 117 bits (293), Expect = 2e-26, Method: Compositional matrix adjust.
Identities = 67/209 (32%), Positives = 113/209 (54%), Gaps = 12/209 (5%)
Frame = +2
Query: 481 PHIVKLIGVITE-NPVWIIMELCTLGELRSFL-----------QVRKYSLDLASLILYAY 528
P+IV +GV E P ++I E C G+L+ FL R +L L+ +
Sbjct: 887 PNIVHFMGVCREAEPHFLITEYCDWGDLKQFLLATRNDNGRGRGTRVPALALSQKLGMGQ 1066
Query: 529 QLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKW 588
Q++ + L ++ VH D+AARNVL++S +K+ LS + S YY + +P++W
Sbjct: 1067 QVAAGMEALSNQGLVHGDLAARNVLLTSRMQLKVARPALSGDVYASEYYPLHQRLVPLRW 1246
Query: 589 MAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCP 648
+ PE + T+ DVW FGV +WE+L P++ + + +V+ +++ + P+ P
Sbjct: 1247 LPPEGVLEDSATTCGDVWAFGVFLWEVLQLADLPYRLMSDEEVLRSLQHSQAALDSPDAP 1426
Query: 649 PTLYSLMTKCWAYDPSRRPRFTELKAQLS 677
P L SL+ +C A PS+RP F+E+ + LS
Sbjct: 1427 PALLSLLQRCTAQQPSQRPPFSEICSVLS 1513
>18996
Length = 491
Score = 110 bits (276), Expect = 2e-24, Method: Compositional matrix adjust.
Identities = 56/136 (41%), Positives = 82/136 (60%), Gaps = 6/136 (4%)
Frame = +2
Query: 543 VHRDIAARNVLVSSNDCVKLGDFGLSRYME-DSTYYKASKGKLPIKWMAPESINFRRFTS 601
+HRD+AARN+LV + CVK+ DFGL+++ D YY S+ +PIKW +PE+I +F+S
Sbjct: 2 IHRDLAARNILVDRS-CVKISDFGLAQFANADGYYYGISQRDIPIKWYSPEAIETCKFSS 178
Query: 602 ASDVWMFGVCMWEILMHG----VKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYS-LMT 656
SDVW +GV ++E+ G + P + + + R+ GERLP P C +YS LM
Sbjct: 179 YSDVWSYGVTLFEMFSRGEIPNLLPGHDLTQEEFLNRLRKGERLPKPELCSDFVYSELMR 358
Query: 657 KCWAYDPSRRPRFTEL 672
CW P RP F ++
Sbjct: 359 PCWHEMPKSRPTFHQI 406
>14477
Length = 493
Score = 108 bits (271), Expect = 9e-24, Method: Compositional matrix adjust.
Identities = 62/169 (36%), Positives = 102/169 (60%), Gaps = 2/169 (1%)
Frame = -1
Query: 416 EIQRERIELGRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSD-SVREKFLQEALT 474
+IQ + ++LG G FG V +G+ ++ + VAIK KN D SV+ + ++EA
Sbjct: 490 QIQMDELKLG----AGNFGSVMKGVC-RLDDREIPVAIKVLKNADLDPSVQSELIKEAEV 326
Query: 475 MRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTAL 534
M++ DH HIV+LIG+ + +++EL LG L FL K+ L L +++ +Q+S +
Sbjct: 325 MKKMDHMHIVRLIGLCEGETMMLVLELAKLGPLNKFLPKNKH-LPLWNILELMWQVSQGM 149
Query: 535 AYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYM-EDSTYYKASKG 582
YLE+ +FVHRD+AARN+L+ K+ DFG+S+ + ++ YY A +
Sbjct: 148 EYLEANKFVHRDLAARNILLCDEHFAKISDFGMSKTLSRENNYYMAQEA 2
>17253
Length = 483
Score = 96.3 bits (238), Expect = 6e-20, Method: Composition-based stats.
Identities = 55/153 (35%), Positives = 88/153 (57%), Gaps = 15/153 (9%)
Frame = -1
Query: 451 VAIKTCKNCTSDSVREKFLQEALTMRQFD-HPHIVKLIGVIT-ENPVWIIMELCTLGELR 508
VA+KT +D+ + +FL+E MR+ HP++V +G T +P I+ME C G+L
Sbjct: 459 VAVKTHNEAATDAEKSEFLRELSIMRKLPRHPNVVSFMGCCTMSDPALILMEFCCHGDLL 280
Query: 509 SFLQVRK---------YSLDLASLILYAYQLSTA--LAYLESKRFVHRDIAARNVLVSSN 557
SFL+ R+ + DL + +++ L A +A++ + + VHRD+AARNVL+S
Sbjct: 279 SFLRKRRPDRTVFLTSTANDLTARDFFSFALHVARGMAHVANNKIVHRDVAARNVLISER 100
Query: 558 DCVKLGDFGLSRYMEDS--TYYKASKGKLPIKW 588
+ K+ DFGLSR + D Y S+ LP++W
Sbjct: 99 NVCKVSDFGLSRRVGDQNDVYEIVSRRPLPLRW 1
>18921
Length = 697
Score = 95.9 bits (237), Expect = 8e-20, Method: Compositional matrix adjust.
Identities = 68/232 (29%), Positives = 114/232 (49%), Gaps = 4/232 (1%)
Frame = +2
Query: 424 LGRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHI 483
LG+ +GEG +G V + ++ LA+ K D+ ++ ++E M+Q D +I
Sbjct: 44 LGK-LGEGSYGSVFKSLHKE-TGQVLAI-----KQVPVDTDLQEIIKEISIMQQCDSKYI 202
Query: 484 VKLIGVITENP-VWIIMELCTLGELRSFLQVRKYSL---DLASLILYAYQLSTALAYLES 539
VK G +N +WI+ME C G + +++R +L ++A+++ Y + L YL S
Sbjct: 203 VKYYGSYFKNTDLWIVMEYCGAGSVSDIMRLRNKTLVEREIATILYYTLK---GLXYLHS 373
Query: 540 KRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRF 599
+R +HRDI A N+L+++ KL DFG++ + D+ + + P WMAPE I +
Sbjct: 374 RRKIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTPY-WMAPEVIQEIGY 550
Query: 600 TSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTL 651
+D+W G+ E + G P I G+ P N PP L
Sbjct: 551 DCVADIWSLGITALE-MAEGKPPVMETS-------IL*GQSS*FPTNAPPPL 682
>22005
Length = 873
Score = 95.9 bits (237), Expect = 8e-20, Method: Compositional matrix adjust.
Identities = 76/249 (30%), Positives = 117/249 (46%), Gaps = 58/249 (23%)
Frame = +1
Query: 426 RCIGEGQFGDVHQGIYMSPENPALAVAI-------------KTCKNCTSDSVREKFLQEA 472
R IG+G FG V + ++ LA + K K S+ ++ F +EA
Sbjct: 1 RDIGQGAFGRVSKLKFL-----GLASLVGELIPEKRP*LL*KMLKEDASEDLQSDFEREA 165
Query: 473 LTMRQFDHPHIVKLIGVIT-ENPVWIIMELCTLGELRSFLQV---RKYSL---------- 518
M FDHP+IVKL+GV P+ ++ E + G+L FL++ Y+L
Sbjct: 166 SLMADFDHPNIVKLLGVCAIGKPMCLLFEFMSKGDLNDFLRLCSPENYNLPVSRSQNLVV 345
Query: 519 ------------------------DLASLI-----LY-AYQLSTALAYLESKRFVHRDIA 548
D + ++ LY + Q+S +AYL K +VHRD+A
Sbjct: 346 DLEDGLRVEVEAEECEKDTQSEDRDCSGMLXTKDQLYISQQISAGMAYLAQKDYVHRDLA 525
Query: 549 ARNVLVSSNDCVKLGDFGLSRYMEDSTYYKAS-KGKLPIKWMAPESINFRRFTSASDVWM 607
R V + + DFGL+R + YY+ S + +PI+WM E+I + +F++ SDVW
Sbjct: 526 TRTVXSRTT*-S*ISDFGLARSVHSVDYYRGSEQDAIPIRWMPLEAILYSKFSTQSDVWS 702
Query: 608 FGVCMWEIL 616
FGV +WEIL
Sbjct: 703 FGVVLWEIL 729
>17637
Length = 447
Score = 89.7 bits (221), Expect = 5e-18, Method: Compositional matrix adjust.
Identities = 46/128 (35%), Positives = 70/128 (54%), Gaps = 1/128 (0%)
Frame = +1
Query: 551 NVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKL-PIKWMAPESINFRRFTSASDVWMFG 609
N ++ VKL D LSR + Y G+ PIKW++ E++ + SDVW FG
Sbjct: 1 NCVIDDQLRVKLTDSALSRDLFSGDYNCLGDGEYRPIKWLSLEALQKSHYNEGSDVWSFG 180
Query: 610 VCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRF 669
V MWE+ G P+ + ++ +++G RL P NCP L+++M CWA P+ RP F
Sbjct: 181 VLMWEMCTLGKLPYAEIDPYEMEHYLKDGYRLAQPFNCPDELFTIMAYCWASMPAERPSF 360
Query: 670 TELKAQLS 677
++L+ LS
Sbjct: 361 SQLQICLS 384
>13305
Length = 549
Score = 87.4 bits (215), Expect = 2e-17, Method: Composition-based stats.
Identities = 37/100 (37%), Positives = 57/100 (57%)
Frame = +2
Query: 583 KLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLP 642
++PI+WMA ES+ +T+ SDVW FGV +WEI G P+ + +++G RL
Sbjct: 8 RVPIRWMAVESLFNNTYTTQSDVWSFGVVLWEIFTLGGTPYSSTDTQQLFAFLKDGYRLK 187
Query: 643 MPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEE 682
P C Y++M +CW + RRP F EL +L +L++
Sbjct: 188 RPKLCDQNTYAMMLQCWNENAQRRPTFPELCGRLQRMLDD 307
>00300
Length = 2318
Score = 87.0 bits (214), Expect = 4e-17, Method: Compositional matrix adjust.
Identities = 74/276 (26%), Positives = 122/276 (44%), Gaps = 13/276 (4%)
Frame = -1
Query: 410 PSTRDYEIQRERIEL----GRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSD--S 463
P DY I R+ G IGEGQFG V+ + MS +A+K K +D
Sbjct: 1700 PREPDYRINVRRVNFRWQRGNKIGEGQFGKVYTAVNMST---GELMALKEMKFQPNDLQQ 1530
Query: 464 VREKFLQEALTMRQFDHPHIVKLIGV-ITENPVWIIMELCTLGELRSFLQVRKYSLDLAS 522
+RE E H ++VK GV + ++ + + ME C G + + K L
Sbjct: 1529 LRE-MCDEIKIFEGIQHENLVKYYGVEVHKDEMLMFMEYCDTGTIE---EAAKMGLPEYL 1362
Query: 523 LILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKG 582
+ Y ++ A+ +L VHRDI N+ ++SN VKLGDFG S ++ T
Sbjct: 1361 IRRYTREIVLAVNHLHENSIVHRDIKGANIFLTSNGHVKLGDFGCSVKLKSHTTMPGEFH 1182
Query: 583 KL--PIKWMAPESINFRR---FTSASDVWMFGVCMWEILMHGVKPFQGVKNN-DVIGRIE 636
L +MAPE + A+D+W G + E+ G +P+ + NN ++ ++
Sbjct: 1181 NLVGTTAYMAPEVFTQNDQGGYGRAADIWSLGCVVIEMAT-GKRPWHDLDNNYQIMYKVG 1005
Query: 637 NGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTEL 672
G + +P + + +DP++R ++L
Sbjct: 1004 IGHKPAVPDSLSVEGKHFLDLIMCHDPAQRALASQL 897
>01718
Length = 959
Score = 86.7 bits (213), Expect = 4e-17, Method: Compositional matrix adjust.
Identities = 73/271 (26%), Positives = 111/271 (40%), Gaps = 14/271 (5%)
Frame = +3
Query: 428 IGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLI 487
IG G F +V + + + + K T S R L+E + + H +I++ +
Sbjct: 171 IGAGFFSEVFKVTH------RITGQVMALKMNTMTSNRHNMLREVQLLNRLQHANILRFM 332
Query: 488 GV-ITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRD 546
GV + E + + E G L L+ + L I L+ L YL S RF+HRD
Sbjct: 333 GVCVHEGQLHALTEYIPSGNLEQLLEKKDEELPWTQRIQLTLGLARGLDYLHSTRFIHRD 512
Query: 547 IAARNVLVSSNDC----VKLGDFGLSRYMEDSTYYKASKGKLPI----KWMAPESINFRR 598
+ ++N+L+ D + DFGL+ + D K KLP WMAPE +N
Sbjct: 513 LTSKNILIRREDNHGYHAVIADFGLATKIPDPL----DKEKLPTVGSPYWMAPEVLNGHF 680
Query: 599 FTSASDVWMFGVCMWEILMH-----GVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYS 653
+ +D++ G+ M EI + P D + E M CP
Sbjct: 681 YNERADLFSVGIIMCEITARIPADPDIMPRMNNFGVDYVALSE------MISYCPLDYLQ 842
Query: 654 LMTKCWAYDPSRRPRFTELKAQLSTILEEEK 684
L KC DP +RPR E+ L I + K
Sbjct: 843 LAFKCCQVDPQKRPRGVEIIEWLEKIFKNLK 935
>19301
Length = 712
Score = 82.8 bits (203), Expect = 6e-16, Method: Compositional matrix adjust.
Identities = 54/170 (31%), Positives = 87/170 (51%), Gaps = 1/170 (0%)
Frame = +2
Query: 400 IIDEEDTYTMPSTRDYEIQRERIELGRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNC 459
II + + D+EI E I +G G G V G + E VA+K ++
Sbjct: 245 IIGKAAAAELKQQDDWEIPFESITDLEWLGSGAQGAVFLGKLCAEE-----VAVKKVRDI 409
Query: 460 TSDSVREKFLQEALTMRQFDHPHIVKLIGVITENPVW-IIMELCTLGELRSFLQVRKYSL 518
+R +R+ +HP+I+ GV T+ P + IIME C G+L L+ K +
Sbjct: 410 KETDIR--------NLRKLNHPNIISFKGVCTQAPCYCIIMEYCPYGQLYEVLRDGK-EI 562
Query: 519 DLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLS 568
A ++ ++ Q+++ + YL S + +HRD+ + NVLV+ ND VK+ DFG S
Sbjct: 563 PPALVLDWSKQIASGMNYLHSHKIIHRDLKSPNVLVAKNDVVKISDFGTS 712
>12721
Length = 821
Score = 77.4 bits (189), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 66/247 (26%), Positives = 103/247 (41%), Gaps = 8/247 (3%)
Frame = +1
Query: 428 IGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLI 487
IGEG G V I S + +AV + RE E + MR + HP+IV++
Sbjct: 112 IGEGSTGIV--CIATSRDGRQMAVKKMDLRK---QQRRELLFNEVVVMRDYHHPNIVEMY 276
Query: 488 G-VITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRD 546
+ + +W++ME G L V +D + ALA+L + +HRD
Sbjct: 277 NSYLVNDELWVVMEFMEGGALTDI--VTNNRMDEVQIATVCRACLKALAFLHANGVIHRD 450
Query: 547 IAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVW 606
I + ++L+S + VKL DFG + + S P WMAPE I+ + D+W
Sbjct: 451 IKSDSILLSHDGKVKLXDFGFCAQVTQDLQKRKSLVGTPY-WMAPEVISRLPYGPEVDIW 627
Query: 607 MFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPP-------NCPPTLYSLMTKCW 659
G+ + E ++ PF + RI + MPP P L + +
Sbjct: 628 SLGIMVME-MIDAEPPFFNEPPLQAMRRIRD-----MPPPKLRNTHKISPRLQGFIDRML 789
Query: 660 AYDPSRR 666
DP +R
Sbjct: 790 VRDPHQR 810
>14420
Length = 528
Score = 74.7 bits (182), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 45/167 (26%), Positives = 78/167 (46%), Gaps = 1/167 (0%)
Frame = +2
Query: 458 NCTSDSVREKFLQEALTMRQFDHPHIVK-LIGVITENPVWIIMELCTLGELRSFLQVRKY 516
N + +E + E L MR+ +P+IV L + +W++ME G L V +
Sbjct: 11 NLSQQPKKELIINEILVMRENQNPNIVNYLDSYLVGEELWVVMEFLAGGSLTDV--VTET 184
Query: 517 SLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTY 576
+D + + AL +L + +HRDI + N+L+ + VKL DFG +
Sbjct: 185 CMDEGQIAAVCRECLQALEFLHENQVIHRDIKSDNILLGMDGSVKLTDFGFCAQLSPEQS 364
Query: 577 YKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPF 623
+++ P WMAPE + +++ D+W GV E ++ G P+
Sbjct: 365 KRSTMVGTP-YWMAPEVVTRKQYGPTVDIWSLGVMCIE-MIEGEPPY 499
>13592
Length = 980
Score = 73.2 bits (178), Expect = 5e-13, Method: Compositional matrix adjust.
Identities = 67/257 (26%), Positives = 118/257 (45%), Gaps = 9/257 (3%)
Frame = +2
Query: 428 IGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEAL-TMRQFDHPHIVKL 486
IG+G+FG V+ + N +A+K ++ K + E L + H ++V+
Sbjct: 8 IGQGRFGKVYTAV---NNNTGELMAMKEIAIQPGETRALKNVAEELKILEGIKHKNLVRY 178
Query: 487 IGV-ITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHR 545
G+ + + I MELC+ G L S +++ L A + QL + +A L VHR
Sbjct: 179 YGIEVHREELLIFMELCSEGTLESLVELTG-GLPEALSRRFTAQLLSGVAELHKHGIVHR 355
Query: 546 DIAARNV-LVSSNDCVKLGDFGLSRYMEDSTYYKAS-KGKLPIK-WMAPE---SINFRRF 599
DI N+ LV ++ +KLGDFG + ++ T +G + + +MAPE N
Sbjct: 356 DIKTANIFLVDGSNSLKLGDFGSAVKIQAHTTVPGELQGYVGTQAYMAPEVFTKTNSDGH 535
Query: 600 TSASDVWMFGVCMWEILMHGVKPFQGVKNN-DVIGRIENGERLPMPPNCPPTLYSLMTKC 658
+D+W G + E + G +P+ +N ++ ++ GE+ P + + + C
Sbjct: 536 GRLADIWSVGCVVVE-MASGKRPWAQFDSNFQIMFKVGMGEKPQAPESLSQEGHDFIDHC 712
Query: 659 WAYDPSRRPRFTELKAQ 675
+DP +R EL Q
Sbjct: 713 LQHDPKQRLSAIELLEQ 763
>27546
Length = 426
Score = 69.3 bits (168), Expect = 7e-12, Method: Composition-based stats.
Identities = 35/114 (30%), Positives = 65/114 (57%), Gaps = 1/114 (0%)
Frame = -1
Query: 462 DSVREKFLQEALTMRQFDHPHIVKLIGVITENP-VWIIMELCTLGELRSFLQVRKYSLDL 520
D V++ F +E + + DHP+I+++ ++ P ++I M G++ S ++ + +D
Sbjct: 357 DFVKKFFPRELEILTRLDHPNIIQIHSILQRGPKIFIFMRYAEKGDMLSHIK-KTGPIDE 181
Query: 521 ASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDS 574
A ++ +Q++ AL YL S HRD+ N+L+S VK+ DFG +RY D+
Sbjct: 180 AQTKVWFFQMAKALQYLHSHDIAHRDLKCENILLSKRLNVKIADFGFARYCRDA 19
>30755
Length = 1137
Score = 68.9 bits (167), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 44/143 (30%), Positives = 76/143 (53%), Gaps = 1/143 (0%)
Frame = +2
Query: 525 LYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKL 584
Y ++ +AL YL S+ ++RD+ N+L+ + +K+ DFGL + ED TY + +K
Sbjct: 44 FYGAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCK--EDITYGRTTKTFC 217
Query: 585 PI-KWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPM 643
+++APE ++ + A D W GV M+E++ G PF +++DV+ + E +
Sbjct: 218 GTPEYLAPEVLDDNDYGRAVDWWGTGVVMYEMIC-GRLPFYN-RDHDVLFTLILVEDVKF 391
Query: 644 PPNCPPTLYSLMTKCWAYDPSRR 666
P N SL++ A DP R
Sbjct: 392 PRNITDEAKSLLSGLLAKDPRNR 460
>00715
Length = 1788
Score = 67.4 bits (163), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 59/253 (23%), Positives = 110/253 (43%), Gaps = 34/253 (13%)
Frame = +1
Query: 449 LAVAIKTCKNCTSDSVREKFLQEALTMR-QFDHPHIVKLIGVIT----ENPVWIIMELCT 503
+AV I ++ ++R+ + E L R H ++V ++G + E+ W+ ME
Sbjct: 7 VAVKIYHKRSSNPRALRQSYSNELLAFRCGLRHVNVVSILGATSLHRFEDGAWLAMEYVG 186
Query: 504 LGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLG 563
L++ L + +D + + A Q++ L YL S VH D+ N L++ + +++
Sbjct: 187 PLNLQTILNDHQQDIDSSMRLSLALQMARGLHYLHSINIVHLDLKPANCLLTRDLKLRIA 366
Query: 564 DFGLSRYM-------------------EDSTYYKASKGKLP--IKWMAPESINFRRFTSA 602
DFG + E + A K +L + + APE + + +
Sbjct: 367 DFGCCHQLTPTGLDMGEREGGMAGNELELTPVQGAWKNELAGTLAYRAPELLKGLQPSVR 546
Query: 603 SDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPT--------LYSL 654
SDV+ G+ +W++ P++GV + V+ ++ + + P PP P T L
Sbjct: 547 SDVYSLGITLWQMCTRQ-GPYEGVPAHAVVYQVVSKDLRPCPP--PSTEDDPFEVMFRDL 717
Query: 655 MTKCWAYDPSRRP 667
T+CWA RP
Sbjct: 718 YTQCWARRVEDRP 756
>13066
Length = 551
Score = 67.0 bits (162), Expect = 4e-11, Method: Compositional matrix adjust.
Identities = 49/174 (28%), Positives = 82/174 (47%), Gaps = 10/174 (5%)
Frame = +3
Query: 446 NPALAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITENPV-WIIMELCTL 504
N LA I + D V + F +E + + DHP+I+++ ++ P +I M
Sbjct: 51 NIKLACKIIDKEKAPVDFVEKFFPRELDLLTKLDHPYIIQIHSILQRXPKNFIFMRFAER 230
Query: 505 GELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGD 564
G+L +++Q + + + I + YQ++TAL YL S HRD+ N+L+SS+ VKL D
Sbjct: 231 GDLLTYIQEVGFVKEKQAKIWF-YQMTTALNYLHSYDVAHRDLKCENILLSSHFNVKLAD 407
Query: 565 FGLS---------RYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFG 609
FG + +YM + A+ I + AP + +D W G
Sbjct: 408 FGFACACITESGEKYMSRTYCGSAAYAAPEIVYGAPYA------PKVADAWSLG 551
>31885
Length = 529
Score = 66.6 bits (161), Expect = 4e-11, Method: Compositional matrix adjust.
Identities = 46/148 (31%), Positives = 77/148 (52%), Gaps = 6/148 (4%)
Frame = -2
Query: 475 MRQFDHPHIVKL-IGVITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTA 533
+ + DHP +V L E ++++++L G+LR +Q ++ S + Y QL+
Sbjct: 510 LTRLDHPFLVNLWYAFQDEEDLFMVVDLFLGGDLRYHMQ-QEVSFREDCVKFYLCQLALV 334
Query: 534 LAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPE- 592
L YL S++ VHRDI N+L+ + DF ++ +ED ++ G P +MAPE
Sbjct: 333 LDYLRSQKIVHRDIKPDNILLDEQGHCHVTDFNIATQLEDDELATSTSGTRP--YMAPEV 160
Query: 593 ---SINFRR-FTSASDVWMFGVCMWEIL 616
+IN RR + D W GV ++E+L
Sbjct: 159 YGVAINERRGYGFPVDWWSLGVSLFELL 76
>07833
Length = 1504
Score = 65.9 bits (159), Expect = 8e-11, Method: Compositional matrix adjust.
Identities = 53/217 (24%), Positives = 99/217 (45%), Gaps = 7/217 (3%)
Frame = -3
Query: 460 TSDSVREKFLQEALTMRQFDHPHIVKLIGVITENP-VWIIMELCTLGELRSFLQVRK-YS 517
+ + F++E +R F+HP+++ ++ + P + +I + G L + L
Sbjct: 1502 VTKRITRDFMEEFPRLRIFNHPNVLPVLACCNQPPNLVLISQFMPFGSLYNTLHGESGIV 1323
Query: 518 LDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYY 577
+D + +A ++ + +L S + N L++S + D M D +
Sbjct: 1322 VDQNQSLRFAMDIARGMEFLHSM-----EPTIPNFLLTSKHVMIDEDLTARINMADYCFS 1158
Query: 578 KASKGKL-PIKWMAPESINFRR---FTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIG 633
KGK+ WMAPE++ R T A+D+W F + MWE+ V PF + + +V
Sbjct: 1157 FHEKGKVYSPAWMAPEALQRRPDDINTRAADMWSFAILMWELETREV-PFAELSSMEVGM 981
Query: 634 RIE-NGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRF 669
++ G R+ +PP + L+ C +P +RPRF
Sbjct: 980 KVALEGLRISIPPGISLHMSRLIKICMNEEPGKRPRF 870
>09606
Length = 1300
Score = 65.1 bits (157), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 68/292 (23%), Positives = 118/292 (40%), Gaps = 37/292 (12%)
Frame = -3
Query: 428 IGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLI 487
+G+G+ +++G N I+ CK R + HP++V+
Sbjct: 1091 LGKGEHSIIYKGRRKGTINFVAIHCIEKCK-------RPEVTNTVRMTHDISHPNVVQFH 933
Query: 488 GVI-TENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRD 546
T N +W+++ELCT G L L + + L S+ + L T L Y+ S + D
Sbjct: 932 EWYETSNHLWLVVELCTGGSLADIL-AQDHHLPETSIRDFGIHLVTGLHYIHSLGILFHD 756
Query: 547 IAARNVLVSSNDCVKLGDFGLSRY----MEDSTYYKASKG-------------KLPIK-- 587
+ VL+ ++ +K DFGLS+ +E+ + A G ++P
Sbjct: 755 LRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQWNIQSAEEMMKQVPTSGS 576
Query: 588 --WMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIEN-------- 637
+MAPE + SD+W G +E + G PF G + ++ N
Sbjct: 575 PTYMAPEVFQGAEPSIMSDLWALGCVFYE-MFSGHPPFLGETYDITKDKVLNKEFPLPKV 399
Query: 638 -GERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTEL------KAQLSTILEE 682
G RL P+ P +L+ D +RR + L + LS++++E
Sbjct: 398 KGSRLSAKPS--PEFLNLLESLLQKDSTRRLSWASLVKHAFWQGGLSSLVKE 249
>14126
Length = 1265
Score = 64.3 bits (155), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 72/296 (24%), Positives = 135/296 (45%), Gaps = 19/296 (6%)
Frame = +3
Query: 369 ALPSIPKLANSEKQGMRTH-AVSVSETDDYAEIIDEEDTYTMPSTRDYEIQRERIELGRC 427
ALP+I ++ +E+ +T AV +T + D + +R + ++ E
Sbjct: 33 ALPTIFRIC*NEESSPKTSPAVRSMKTAISPKGRDGQSESAAKMSRRRDSTEQKYEEVAV 212
Query: 428 IGEGQFGDVHQGIYMSPENPALAVAIKTCK-NCTSDSVREKFLQEALTMRQ---FDHPHI 483
IG G +G V++ + N VA+K + N T + + ++E ++Q ++HP++
Sbjct: 213 IGNGAYGTVYKARDL--RNQGEFVAMKRIRLNNTEEGMPMMAIREISMLKQLEQYEHPNV 386
Query: 484 VKLIGVITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYA--------------YQ 529
V+L+ V + N + T E+R L DLA+ + Q
Sbjct: 387 VRLLDV-SHNTI-------TDREIRLNLVFEYIEHDLATYLAKCPSPGLGPDRIKDLMLQ 542
Query: 530 LSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWM 589
L + +L S R VHRD+ +N+L+S + +KL DFGL+R S + + + + +
Sbjct: 543 LLNGVDFLHSNRIVHRDLKPQNLLISKDGRLKLADFGLARIY--SFHMALTTVVVTLWYR 716
Query: 590 APESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPP 645
+PE + + ++ D+W G C++ L F+G D + +I E + +PP
Sbjct: 717 SPEVLMQAEYGTSVDIWSCG-CIFAELFTRRALFKGSSEFDQLKKI--FEVIGLPP 875
>01060
Length = 1800
Score = 62.8 bits (151), Expect = 7e-10, Method: Compositional matrix adjust.
Identities = 48/196 (24%), Positives = 100/196 (51%), Gaps = 6/196 (3%)
Frame = +1
Query: 428 IGEGQFGDVHQGIYMSPENPALAVAIKTCK-NCTSDSVREKFLQEALTMRQFDHPHIVKL 486
IGEG +G V++ + + +A+K + + D V ++E +R+ H +IV L
Sbjct: 97 IGEGTYGVVYKCRHRATGR---KLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTNIVCL 267
Query: 487 IGVITENP-VWIIMELCTLGELRSFLQV--RKYSLDLASLILYAYQLSTALAYLESKRFV 543
VI E+ ++++ E ++ +L+ ++ LD + Y +Q+ T + + +R V
Sbjct: 268 EDVIMEDERLFLVFEFLSM-DLKMYIDKFPEGVVLDRRLVKSYVFQIVTGIXFCHQRRIV 444
Query: 544 HRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWM-APESI-NFRRFTS 601
HRD+ +N+L++ +K+ DFG++R + +A ++ W APE + ++++
Sbjct: 445 HRDLKPQNLLINHTGAIKIADFGMARTF--ALPVRAYTHEVVTLWYRAPEILMGASKYST 618
Query: 602 ASDVWMFGVCMWEILM 617
DVW G ++L+
Sbjct: 619 PVDVWSIGTIFADMLI 666
>19094
Length = 898
Score = 61.6 bits (148), Expect = 1e-09, Method: Composition-based stats.
Identities = 34/114 (29%), Positives = 62/114 (54%), Gaps = 3/114 (2%)
Frame = +1
Query: 505 GELRSFLQVRKYSL---DLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVK 561
G + +++R +L ++A+++ Y + L YL S+R +HRDI A N+L+++ K
Sbjct: 10 GSVSDIMRLRNKTLVEREIATILYYTLK---GL*YLHSRRKIHRDIKAGNILLNNEGHAK 180
Query: 562 LGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEI 615
L DFG++ + D+ + + P WMAPE I + +D+W G+ E+
Sbjct: 181 LADFGVAGQLTDTMAKRNTVIGTPY-WMAPEVIQEIGYDCVADIWSLGITALEM 339
>13212
Length = 1067
Score = 61.2 bits (147), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 51/196 (26%), Positives = 84/196 (42%), Gaps = 18/196 (9%)
Frame = -1
Query: 495 VWIIMELCTL---GELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARN 551
VW I+++ + G L S + + + A + +++ AL +L +HRDI A N
Sbjct: 1067 VWXIVDVFRVLWWGALDSIMVDLEKPMTEAQICYVCHEMCMALDFLHRHHVIHRDIKAGN 888
Query: 552 VLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAP-----ESINFRRFTSASDVW 606
VL++ + VKL DFG+S + + + P WMAP E++ + +D+W
Sbjct: 887 VLLTIDGEVKLADFGVSAKNTQTQQKRDTFIGTPY-WMAPEVVLCETLKDTPYDFKADIW 711
Query: 607 MFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTL----------YSLMT 656
GV + E P + + V+ +I + PPTL +
Sbjct: 710 SLGVTLIE-FAQIEPPNKEMHPMRVLIKIHKSD--------PPTLEKPKKWTKLFKDFIA 558
Query: 657 KCWAYDPSRRPRFTEL 672
KC DP+ RP EL
Sbjct: 557 KCLVKDPNLRPTAAEL 510
>29581
Length = 1278
Score = 60.1 bits (144), Expect = 5e-09, Method: Compositional matrix adjust.
Identities = 49/163 (30%), Positives = 78/163 (47%), Gaps = 8/163 (4%)
Frame = -2
Query: 464 VREKFLQEALTMRQFDHPHIVKLIGVI---TENPVWIIMELCTLGELRSFLQVRKYSLDL 520
VR FL L +R H +IV+L V+ + + ++++ME C +L S L
Sbjct: 1208 VRSTFL---LNLR---HQNIVQLQEVVVGKSLDSLFLVMEYCE-QDLASLLDNMPAPFSE 1050
Query: 521 ASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKAS 580
+ + QL L YL +HRD+ N+L++ CVK+ DFGL+R Y K
Sbjct: 1049 SQVKCIVLQLLKGLRYLHEAFIIHRDLKVSNLLMTDKGCVKIADFGLAR-----NYGKPQ 885
Query: 581 KGKLP----IKWMAPESI-NFRRFTSASDVWMFGVCMWEILMH 618
K P + + APE + + ++A D+W G + E+L H
Sbjct: 884 KPMTPKVVTLWYRAPELLFGSKTHSTAIDMWSAGCILGELLGH 756
>19761
Length = 473
Score = 58.9 bits (141), Expect = 9e-09, Method: Compositional matrix adjust.
Identities = 34/130 (26%), Positives = 67/130 (51%), Gaps = 8/130 (6%)
Frame = -3
Query: 523 LILYAYQLSTALAYLESKR--FVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKAS 580
++ + Q ++AL Y+ + +HRD+ +N+ V+ V+LGD GL+R + + S
Sbjct: 417 IVCWLMQTASALNYMHTHTPVILHRDLKPQNIYVTEKGDVRLGDLGLARKLTGPADFATS 238
Query: 581 KGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIG------R 634
+ I +++PE ++ + + S SD+W G ++I G K +D +G +
Sbjct: 237 QVG-TIMYLSPEILSQQPYNSKSDIWSLGCVFYDI--------TGKKGSDEMGVMFLLVQ 85
Query: 635 IENGERLPMP 644
+ G +LP+P
Sbjct: 84 VMGGRKLPLP 55
>01756
Length = 1858
Score = 58.9 bits (141), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 49/204 (24%), Positives = 90/204 (44%), Gaps = 16/204 (7%)
Frame = -3
Query: 428 IGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKF----LQEALTMRQFDHPHI 483
IG+G FG+V + + VA+K D+ +E F L+E ++ +H ++
Sbjct: 1718 IGQGTFGEVFKA---RCKKTKQVVAMK---KVLMDNEKEGFPITALREIKILQLLNHENV 1557
Query: 484 VKLIGVIT---------ENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTAL 534
V LI + + ++ +++ E C +L L +L + QL L
Sbjct: 1556 VDLIEICSTKATSANRYKSMFYLVFEFCE-HDLAGLLSNMSVVFNLPEIKEVMKQLMNGL 1380
Query: 535 AYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSR-YMEDSTYYKASKGKLPIKWMAPES 593
Y+ + +HRD+ A N+L++ +KL DFGL+R + + ++ W P
Sbjct: 1379 YYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRPPE 1200
Query: 594 INF--RRFTSASDVWMFGVCMWEI 615
+ R +++A D W G M E+
Sbjct: 1199 LLLGDRNYSTAIDQWGAGCIMAEM 1128
>04591
Length = 1117
Score = 58.2 bits (139), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 46/167 (27%), Positives = 75/167 (44%), Gaps = 16/167 (9%)
Frame = -2
Query: 469 LQEALTMRQFDHPHIVKLIGVI---------TENPVWIIMELCTLGELRSFLQVRKYSLD 519
L+E ++Q +H ++V+L + ++ ++I E C +L L +
Sbjct: 1077 LREIKILQQLEHENVVQLQEICHTQAGPYNRYKSTFYLIFEYCDY-DLAGLLNNLRVKFS 901
Query: 520 LASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKA 579
LA QL L Y+ +K+ +HRDI A N+L++ + +KL DFGLSR S K
Sbjct: 900 LADKKNLMSQLLNGLFYIHTKQILHRDIKAANILLTRDGVLKLADFGLSRPWVKS---KR 730
Query: 580 SKGKLPIKWMAPESINF--RRFTSASDVWMFGVCMWEI-----LMHG 619
++ W P + R + D+W G M E+ LM G
Sbjct: 729 LTNRVVTLWYRPPELLLGEREYGPEIDMWGVGCIMAEMWSRKPLMQG 589
>03240
Length = 1683
Score = 56.6 bits (135), Expect = 4e-08, Method: Compositional matrix adjust.
Identities = 63/263 (23%), Positives = 108/263 (41%), Gaps = 56/263 (21%)
Frame = -3
Query: 417 IQRERIELGRC-------IGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFL 469
I+ +R ++ +C +G G FG+V + + A+KT + SD ++ +
Sbjct: 1321 IRLKRAKMDKCMFEKIKTLGVGAFGEVS---LCRKNDTGMLYAMKTLRK--SDVLKRNQV 1157
Query: 470 QEALTMRQF----DHPHIVKLIGVITE-NPVWIIMELCTLGELRSFLQVRKYSLDLASLI 524
R D+ +VKL + N ++ +M+ G+L L +R LD
Sbjct: 1156 AHVKAERDILAEADNEWVVKLYYSFQDHNYLYFVMDYVPGGDLMGLL-IRMEILDEPLAR 980
Query: 525 LYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLS---RYMEDSTYYK--- 578
Y +L A+ + F+HRDI N+L+ N +KL DFGL R+ +S YY+
Sbjct: 979 FYVAELVQAIESVHRMGFIHRDIKPDNILIDRNGHIKLTDFGLCTGFRWTHNSKYYQRDG 800
Query: 579 --ASKGKLPIK-----------------------------------WMAPESIN-FRRFT 600
A + + +K ++APE ++ +T
Sbjct: 799 THARQDSMEVKCQLDEQCQCEILKPLERRRKREQRCLAHSLVGTPNYIAPEVLSRLGGYT 620
Query: 601 SASDVWMFGVCMWEILMHGVKPF 623
S D W GV ++E+L+ G PF
Sbjct: 619 SVCDWWSVGVILFEMLV-GHPPF 554
>21079
Length = 878
Score = 56.6 bits (135), Expect = 5e-08, Method: Compositional matrix adjust.
Identities = 34/128 (26%), Positives = 66/128 (51%), Gaps = 2/128 (1%)
Frame = +1
Query: 497 IIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSS 556
++ME GEL + + L + + Q+ + + Y+ ++ +H D+ NVL S
Sbjct: 55 LVMEFVGAGELFERVIRDDFVLTERDCVHFVRQICSGVGYMHTQSILHLDLKPENVLCVS 234
Query: 557 NDC--VKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWE 614
++ +K+ DFGL+R+ + + G P +++APE +N+ +D+W GV +
Sbjct: 235 DNSNQIKIIDFGLARFYKPGDSLQVLFGT-P-EFIAPEVVNYDEINFTTDMWSIGVICY- 405
Query: 615 ILMHGVKP 622
IL+ G+ P
Sbjct: 406 ILLSGLSP 429
>01707
Length = 757
Score = 55.8 bits (133), Expect = 8e-08, Method: Compositional matrix adjust.
Identities = 53/199 (26%), Positives = 90/199 (45%), Gaps = 10/199 (5%)
Frame = +1
Query: 428 IGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKF-LQEALTMRQFDHPHIVKL 486
IGEG +G V + + + VAIK D + +K ++E ++Q HP++V+L
Sbjct: 88 IGEGSYGVVFK---CRNKETSQLVAIKKFVESEDDPLIKKIAMREIRMLKQLKHPNLVRL 258
Query: 487 IGVITENP----VWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRF 542
I V V+ ++ L EL + R + I+Y Q A+ +
Sbjct: 259 IEVFRRKKRLHLVFDYVDHTLLNELDRY--PRGLPEPMVKRIIY--QTLLAVNFCHQYNT 426
Query: 543 VHRDIAARNVLVSSNDCVKLGDFGLSRYM----EDSTYYKASKGKLPIKWMAPE-SINFR 597
+HRD+ N+L++ VKL DFG +R + ++ T Y A++ + APE +
Sbjct: 427 IHRDVKPENILITRQGQVKLCDFGFARILTGPGDEYTDYVATRW-----YRAPELLVGDT 591
Query: 598 RFTSASDVWMFGVCMWEIL 616
++ DVW G E+L
Sbjct: 592 QYGPPVDVWAIGCVFAELL 648
>18484
Length = 635
Score = 55.5 bits (132), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 28/113 (24%), Positives = 59/113 (52%)
Frame = +1
Query: 525 LYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKL 584
YA +++ L +L + ++RD+ NV++ S +K+ DFG+ + +
Sbjct: 55 FYAAEIAVGLFFLHDQGIIYRDLKLDNVMLDSEGHIKIADFGMCKEGMTGDATTRTFCGT 234
Query: 585 PIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIEN 637
P ++APE + ++ ++ + D W +GV ++E+L G PF G +++ I +
Sbjct: 235 P-DYIAPEIVLYQPYSKSVDWWAYGVLLFEMLA-GQPPFDGEDEDELFSSITD 387
>07836
Length = 1478
Score = 54.3 bits (129), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 65/260 (25%), Positives = 112/260 (43%), Gaps = 43/260 (16%)
Frame = -1
Query: 465 REKFLQEALTMRQFDHPHIVKLI-----GVITENPVWIIMELCTLGELRSFLQVRKYSLD 519
RE L + + +R H +I+ I G + +++I + G L +L R LD
Sbjct: 1424 RETELYQTVLLR---HENILGFIAADIKGTGSWTQLFLITDYHENGSLHDYLLSR--VLD 1260
Query: 520 LASLILYAYQLSTALAYLESKRF--------VHRDIAARNVLVSSNDCVKLGDFGLS-RY 570
+ ++ A+ LA+L + F HRDI ++N+LV N + D GL+ RY
Sbjct: 1259 SSEMLALAHSAICGLAHLHIEIFGTRGKPAIAHRDIKSKNILVKKNGTCCIADLGLAVRY 1080
Query: 571 MEDSTYYKASKG--KLPIKWMAPESI-------NFRRFTSASDVWMFGVCMWEI----LM 617
+ +S + + ++MAPE + NF F A D++ FG+ MWEI ++
Sbjct: 1079 ISESNEVDVAPNPRQGTKRYMAPEVLEMLLNVKNFDAFKQA-DMYAFGLVMWEIARCCVI 903
Query: 618 HGVK-----PFQGVKNND--------VIGRIENGERLPMPPNCPP---TLYSLMTKCWAY 661
GV PF +D V+ + +P+ P + +M +CW+
Sbjct: 902 GGVAEEYQVPFYNCLPHDPSFEDVRLVVSVDKVRPDIPLRWQEDPIMKVMVKVMCECWSG 723
Query: 662 DPSRRPRFTELKAQLSTILE 681
+P+ R +K L + E
Sbjct: 722 NPAARLTALRVKKTLGKLSE 663
>01966
Length = 1735
Score = 53.5 bits (127), Expect = 4e-07, Method: Compositional matrix adjust.
Identities = 30/113 (26%), Positives = 62/113 (54%), Gaps = 3/113 (2%)
Frame = -1
Query: 460 TSDSVREKFLQEALTMRQFDHPHIVKLIGVITENP-VWIIMELCTLGELRSFLQV--RKY 516
+ D V ++E +R+ H +IV L VI E+ ++++ E ++ +L+ ++
Sbjct: 1597 SEDGVPSSAIREIAMLRELRHTNIVCLEDVIMEDERLFLVFEFLSM-DLKMYIDKFPEGV 1421
Query: 517 SLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSR 569
LD + Y +Q+ T + + +R VHRD+ +N+L++ +K+ DFG++R
Sbjct: 1420 VLDRRLVKSYVFQIVTGINFCHQRRIVHRDLKPQNLLINHTGAIKIADFGMAR 1262
>26711
Length = 405
Score = 50.8 bits (120), Expect = 2e-06, Method: Composition-based stats.
Identities = 32/102 (31%), Positives = 58/102 (56%), Gaps = 5/102 (4%)
Frame = -2
Query: 529 QLSTALAYLESKRFVHRDIAARNVLVSSN--DCVKLGDFGLSRYM---EDSTYYKASKGK 583
Q+ L ++ ++ VH D+ N+L+S + D V+L DFGL+R + +++ + G
Sbjct: 392 QVLDILQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARKLYPPQETFLNHGTPG- 216
Query: 584 LPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQG 625
+ +PE+++ + ++ASDVW GV + IL+ G PFQ
Sbjct: 215 ----FTSPEALDVKPISTASDVWGVGVLAY-ILLSGQSPFQA 105
>15910
Length = 1361
Score = 50.8 bits (120), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 34/110 (30%), Positives = 56/110 (50%), Gaps = 3/110 (2%)
Frame = +2
Query: 533 ALAYLESKRFVHRDIAARNVL---VSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWM 589
+ Y+ + VHRD+ N+L ++ + +KL DFGLSR +E G P +
Sbjct: 500 GVQYIHANGVVHRDLKPENLLYECMTDDSKLKLADFGLSRIIEPEVQMSTVCGT-P-GYC 673
Query: 590 APESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGE 639
APE + ++T + D+W GV + IL+ G +PF ++ +I GE
Sbjct: 674 APEVLKGDKYTPSVDMWSVGVIAY-ILLCGYEPFFAENEFEMYRKIIKGE 820
>25550
Length = 941
Score = 48.9 bits (115), Expect = 9e-06, Method: Compositional matrix adjust.
Identities = 25/76 (32%), Positives = 37/76 (48%), Gaps = 1/76 (1%)
Frame = +3
Query: 608 FGVC-MWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRR 666
G C +W++ + GV +V +E G R+ P P +Y LM KCW +DP R
Sbjct: 12 MGACDIWDVX------YPGVDLTEVYHLLERGYRMERPQGTPADVYILMLKCWQWDPKER 173
Query: 667 PRFTELKAQLSTILEE 682
P F E+ L + E+
Sbjct: 174 PTFKEIHYLLENMFEK 221
>12672
Length = 773
Score = 48.9 bits (115), Expect = 9e-06, Method: Compositional matrix adjust.
Identities = 38/162 (23%), Positives = 66/162 (40%), Gaps = 16/162 (9%)
Frame = +3
Query: 531 STALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGL---SRYMEDSTYYKASKGKLPIK 587
++ + YL VHRDI N+L+ S K+GDF + E T AS
Sbjct: 21 ASGIQYLNDNGHVHRDIKTANILLDSEYTAKVGDFATVVSAPSGEGKTVQNASVVIGTAA 200
Query: 588 WMAPESINFRRFTSASDVWMFGVCMWEILMHGVKP-------------FQGVKNNDVIGR 634
++APE+I+F ++ D + FGV + E++ V + V+ + I
Sbjct: 201 YLAPEAIHF-DVSTKLDSYSFGVVLLEVITGLVAQDYSREERTLSSHIMENVEEPEEIHD 377
Query: 635 IENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQL 676
+ P LY + +C +RP +++ +L
Sbjct: 378 FVDQSAGTWPDGAVDKLYDISMRCLNLSKKQRPNVKDIRPEL 503
>32264
Length = 287
Score = 48.5 bits (114), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 21/48 (43%), Positives = 28/48 (58%)
Frame = +1
Query: 635 IENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEE 682
IE+G RL P P ++Y LM +CW Y P +RP F EL L I+ +
Sbjct: 1 IEDGYRLQQNPQTPDSVYKLMLRCWEYVPEKRPHFKELYTSLKDIVRK 144
>21433
Length = 590
Score = 48.1 bits (113), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 30/98 (30%), Positives = 49/98 (50%)
Frame = +2
Query: 526 YAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLP 585
Y YQLS+AL Y ++ +HRDI N+L+ +K+ DFG S + S + +
Sbjct: 182 YIYQLSSALEYCHYRKVIHRDIKPENLLLGLKGDLKIADFGWSVHAPSS---RRTTMCGT 352
Query: 586 IKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPF 623
+ ++ PE + + D+W GV +E L+ G P
Sbjct: 353 LDYLPPEMVEGKTHDENVDLWSLGVLCYEFLV-GTPPL 463
>28157
Length = 400
Score = 46.6 bits (109), Expect = 5e-05, Method: Compositional matrix adjust.
Identities = 31/112 (27%), Positives = 54/112 (48%), Gaps = 6/112 (5%)
Frame = +3
Query: 461 SDSVREKFLQEALTMRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVR--KYSL 518
S+ ++ F+QE + + HP+IV L G ++PV ++ME G L + L +
Sbjct: 30 SEQEKKSFMQELKQLSRVSHPNIVCLYGACRDHPVCLVMEYAEGGSLYNVLHGSGPQPQY 209
Query: 519 DLASLILYAYQLSTALAYLES---KRFVHRDIAARN-VLVSSNDCVKLGDFG 566
A + + Q + + YL K +HRD+ N +L+ +K+ DFG
Sbjct: 210 TAAHAMNWLLQCALGVEYLHGMKPKALIHRDLKPPNLLLIQCGTKLKICDFG 365
>26560
Length = 398
Score = 44.3 bits (103), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 32/113 (28%), Positives = 58/113 (51%), Gaps = 1/113 (0%)
Frame = -1
Query: 525 LYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKL 584
YA ++ L ++ S+ V+RD+ N+L+ N V++ D GL+ D + +
Sbjct: 344 FYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGLA---CDFSKKRPHASVG 174
Query: 585 PIKWMAPESI-NFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIE 636
+MAPE + + + S++D + FG CM L+ G PF+ ++N RI+
Sbjct: 173 THGYMAPEVLMKGQSYDSSADWFSFG-CMLYKLLKGHSPFR--QHNQGQARID 24
>04138
Length = 800
Score = 43.5 bits (101), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 24/85 (28%), Positives = 42/85 (49%), Gaps = 3/85 (3%)
Frame = +1
Query: 534 LAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSR-YMEDSTYYKASKGKLPIKWMAPE 592
L Y+ + +HRD+ A N+L++ +KL DFGL+R + + ++ W P
Sbjct: 52 LYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRPP 231
Query: 593 SINF--RRFTSASDVWMFGVCMWEI 615
+ R +++A D W G M E+
Sbjct: 232 ELLLGDRNYSTAIDQWGAGCIMAEM 306
>01392
Length = 1806
Score = 42.4 bits (98), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 37/123 (30%), Positives = 59/123 (47%), Gaps = 12/123 (9%)
Frame = -1
Query: 521 ASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSND---CVKLGDFGLSRYME-DSTY 576
ASL++ ++ AL +L SK HRD+ N+L D VK+ DF L+ + D
Sbjct: 1785 ASLVVR--HIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGISCDGDG 1612
Query: 577 YKASKGKLPI---KWMAPESINFRRFTSAS-----DVWMFGVCMWEILMHGVKPFQGVKN 628
K + P+ ++MAPE ++ S S D+W G+ ++ I++ G PF G
Sbjct: 1611 TKTPELLTPVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILY-IMLCGYPPFYGQCG 1435
Query: 629 NDV 631
D
Sbjct: 1434 EDC 1426
>12786
Length = 460
Score = 41.6 bits (96), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 39/143 (27%), Positives = 69/143 (48%), Gaps = 23/143 (16%)
Frame = -3
Query: 517 SLDLASLILYAYQLSTALAYLESKRFVHRDIAARN-VLVSSNDCVKLGDFGLSRYMED-- 573
LD + Y ++ A+ L ++ +H D+ N +LV+ N +KL DFG++ ++
Sbjct: 422 GLDRMMIKFYWREMLRAVKALHNEGVIHSDLKPANFMLVAGN--LKLIDFGIANTLQQDK 249
Query: 574 STYYKASKGKLPIKWMAPESINFRRFTSA--------------------SDVWMFGVCMW 613
++ K S+ P +M+PE+I SA SDVW G C+
Sbjct: 248 TSVLKDSRVGTP-SYMSPEAIMAACDDSADDSMEEDGHRTKPKYKVGVRSDVWSLG-CIL 75
Query: 614 EILMHGVKPFQGVKNNDVIGRIE 636
+++G PFQ +KNN +G+++
Sbjct: 74 YNMVYGRTPFQHIKNN--MGKLQ 12
>07933
Length = 728
Score = 40.0 bits (92), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 15/39 (38%), Positives = 26/39 (66%)
Frame = +3
Query: 644 PPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEE 682
P CP LY++M +CW+ +PS RP F +L+ + ++E+
Sbjct: 3 PNYCPNLLYNIMMQCWSAEPSARPTFHKLEQDIVAMVEQ 119
>03508
Length = 1463
Score = 40.0 bits (92), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 26/100 (26%), Positives = 48/100 (48%), Gaps = 2/100 (2%)
Frame = +1
Query: 525 LYAYQLSTALAYLESKRFVHRDIAARNVLVS-SNDCVKLGDFGLSRYMEDSTYYKASKGK 583
Y Y+L AL + S +HRD+ NV++ N ++L D+GL+ + Y
Sbjct: 883 FYLYELMKALDFCHSMGIMHRDVKPHNVMIDHENKKLRLIDWGLAEFYHPGMEYNVRVAS 1062
Query: 584 LPIKWMAPE-SINFRRFTSASDVWMFGVCMWEILMHGVKP 622
K PE ++++ + + D+W G CM+ ++ +P
Sbjct: 1063RYFK--GPELLLDYQMYDYSLDMWSLG-CMFASMIFRKEP 1173
>37602
Length = 804
Score = 38.5 bits (88), Expect = 0.014, Method: Compositional matrix adjust.
Identities = 22/71 (30%), Positives = 32/71 (45%)
Frame = -1
Query: 495 VWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLV 554
+WI ME C G ++ V L + + L YL + +HRDI N+L+
Sbjct: 294 LWIAMEYCGGGSMQDIYHVTG-PLTEPQIAFVCRETLKGLHYLHRRGKMHRDIKGANILL 118
Query: 555 SSNDCVKLGDF 565
+ VKL DF
Sbjct: 117 TEEGDVKLADF 85
>38046
Length = 446
Score = 38.1 bits (87), Expect = 0.017, Method: Composition-based stats.
Identities = 14/32 (43%), Positives = 24/32 (75%)
Frame = -1
Query: 530 LSTALAYLESKRFVHRDIAARNVLVSSNDCVK 561
++ A+AY+E + F+HR++ RN+LV N+ VK
Sbjct: 98 IADAMAYMEKENFIHRNLGDRNILVGPNNRVK 3
>11185
Length = 473
Score = 37.4 bits (85), Expect = 0.032, Method: Compositional matrix adjust.
Identities = 37/168 (22%), Positives = 62/168 (36%), Gaps = 21/168 (12%)
Frame = +1
Query: 526 YAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRY----MEDSTYYKASK 581
+ L T L Y+ S + D+ VL+ ++ +K DFGLS+ +E+ + A
Sbjct: 16 FGIHLVTGLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEA 195
Query: 582 G-------------KLPIK----WMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQ 624
G ++P +MAPE + SD+W G +E+
Sbjct: 196 GDQWNIQSAEEMMKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMF-------- 351
Query: 625 GVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTEL 672
+G RL P+ P +L+ D +RR + L
Sbjct: 352 ------------SGSRLSAKPS--PEFLNLLESLLQKDSTRRLSWASL 453
>18481
Length = 437
Score = 37.4 bits (85), Expect = 0.033, Method: Composition-based stats.
Identities = 26/82 (31%), Positives = 44/82 (53%), Gaps = 4/82 (4%)
Frame = -1
Query: 497 IIMELCTLG-ELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVS 555
++MEL LG L + K L ++++ + QL + L ++ K F+HRD+ N L+
Sbjct: 266 LVMEL--LGPSLEELFVICKRRFTLKTILMVSDQLLSRLEFIHQKCFIHRDLKPDNFLMG 93
Query: 556 -SNDCVKLG--DFGLSRYMEDS 574
C +L DFGLS+ +D+
Sbjct: 92 LGRHCHRLYIIDFGLSKRYKDT 27
>02638
Length = 1490
Score = 36.6 bits (83), Expect = 0.056, Method: Composition-based stats.
Identities = 28/92 (30%), Positives = 42/92 (45%), Gaps = 5/92 (5%)
Frame = +1
Query: 586 IKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKP---FQGVKNN-DVIGRIENG-ER 640
I +MAPE + + A DVW G M E M +P + N+ +I +I + +
Sbjct: 28 IAFMAPEVLRGESYGRACDVWSVGCVMIE--MCTCRPPWNSHDISNHLALIFKIASSVDP 201
Query: 641 LPMPPNCPPTLYSLMTKCWAYDPSRRPRFTEL 672
P+P N P + LM +C D RP +L
Sbjct: 202 PPIPENMSPPVRDLMLRCLEQDSDFRPSAKDL 297
>00486
Length = 797
Score = 34.7 bits (78), Expect = 0.19, Method: Compositional matrix adjust.
Identities = 24/81 (29%), Positives = 36/81 (44%)
Frame = -2
Query: 586 IKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPP 645
I++MAPE + A D W G M+++L G PF I +I G +L +PP
Sbjct: 766 IEYMAPEILTRTGHGKAVDWWSLGALMYDMLT-GSPPFTAENRKKTIDKILKG-KLNLPP 593
Query: 646 NCPPTLYSLMTKCWAYDPSRR 666
L+ K +P+ R
Sbjct: 592 YLTNEARGLIKKLLRKNPAER 530
>26009
Length = 886
Score = 34.7 bits (78), Expect = 0.20, Method: Compositional matrix adjust.
Identities = 15/30 (50%), Positives = 21/30 (70%)
Frame = +3
Query: 529 QLSTALAYLESKRFVHRDIAARNVLVSSND 558
QL +AL ++ SK+ VHRDI NVL+ + D
Sbjct: 735 QLVSALDFMHSKQLVHRDIKPENVLILTPD 824
>16708
Length = 1397
Score = 34.3 bits (77), Expect = 0.28, Method: Compositional matrix adjust.
Identities = 17/49 (34%), Positives = 27/49 (55%)
Frame = -1
Query: 521 ASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSR 569
A + A Q AL ++ VH D+ A NVLV ++ KL D+G+++
Sbjct: 1094 AMVCCIAGQXVCALEHIHELGVVHMDVKADNVLVDAHGNCKLTDYGIAQ 948
>15741
Length = 402
Score = 33.9 bits (76), Expect = 0.34, Method: Composition-based stats.
Identities = 15/44 (34%), Positives = 24/44 (54%)
Frame = -3
Query: 510 FLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVL 553
FL L +A ++ +A++ + + VHRD+AARNVL
Sbjct: 133 FLTSTANDLTARDFFSFALHVARGMAHVANNKIVHRDVAARNVL 2
>27287
Length = 514
Score = 33.9 bits (76), Expect = 0.35, Method: Compositional matrix adjust.
Identities = 13/37 (35%), Positives = 20/37 (54%)
Frame = -2
Query: 644 PPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTIL 680
PP ++ +M CW DP+ RP F+ L +L +L
Sbjct: 504 PPYASSEMFGIMHSCWQEDPNDRPSFSRLVQELDKML 394
>27405
Length = 532
Score = 33.9 bits (76), Expect = 0.38, Method: Compositional matrix adjust.
Identities = 22/83 (26%), Positives = 39/83 (46%)
Frame = -3
Query: 525 LYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKL 584
YA ++ L ++ S+ V+RD+ N+L+ N V++ D GL+ D + K
Sbjct: 242 FYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGLAC---DFSKKKPHASVG 72
Query: 585 PIKWMAPESINFRRFTSASDVWM 607
+MAPE + + +S W
Sbjct: 71 THGYMAPEVLMKGQAYDSSADWF 3
>21210
Length = 518
Score = 32.7 bits (73), Expect = 0.74, Method: Compositional matrix adjust.
Identities = 30/104 (28%), Positives = 47/104 (45%), Gaps = 7/104 (6%)
Frame = +3
Query: 588 WMAPESINFRR----FTSASDVWMFGVCMWEILMHGVKPFQG-VKNNDVIGRIENGER-- 640
+MAPE I+ R + SDVW G+ + E L G P++ V D + ++ G
Sbjct: 18 YMAPERIDPRASSHGYDVRSDVWSLGITLME-LATGRFPYRKWVSIFDQLQQVVRGVAPC 194
Query: 641 LPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEK 684
LP + + KC D +RP++ +L A L EE+
Sbjct: 195 LPHDGAFSHDFVNFVNKCLTKDEKQRPKYNKLLAHPFVRLYEEQ 326
>25019
Length = 730
Score = 31.6 bits (70), Expect = 1.8, Method: Composition-based stats.
Identities = 22/62 (35%), Positives = 29/62 (46%)
Frame = +3
Query: 548 AARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWM 607
AA NVL+ + VKL DFGL + T + I++MAPE + A D W
Sbjct: 255 AAENVLLDKDGHVKLTDFGLCKEAITGTRVTHTFCG-TIEYMAPEILTRTGHGKAVDWWS 431
Query: 608 FG 609
G
Sbjct: 432 LG 437
>32359
Length = 928
Score = 30.4 bits (67), Expect = 3.8, Method: Compositional matrix adjust.
Identities = 35/128 (27%), Positives = 60/128 (46%), Gaps = 9/128 (7%)
Frame = -1
Query: 425 GRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIV 484
+ IG G FG V+Q + + + VAIK K + + LQ MR+ +H +IV
Sbjct: 415 AKVIGNGSFGVVYQAKLV---DTSELVAIK--KVLQDKRFKNRELQ---IMRKLEHQNIV 260
Query: 485 KLIGVI-----TENPVWI--IMELC--TLGELRSFLQVRKYSLDLASLILYAYQLSTALA 535
KL ++ V++ ++E T+ + K ++ + + LY YQL +LA
Sbjct: 259 KLKFFFYSSGEKKDEVFLNLVLEYVPETVYRVARHYSKSKQTIPILYIKLYMYQLFRSLA 80
Query: 536 YLESKRFV 543
Y+ S+ V
Sbjct: 79 YIHSQACV 56
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000378649 | hsapiens_gene_ensembl | Focal adhesion
kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK) (Protein- tyrosine kinase
2). [Source:Uniprot/SWISSPROT;Acc:Q05397]
(1073 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
06405 221 1e-57
21808 199 4e-51
11780 121 1e-44
09007 176 6e-44
04852 162 7e-40
14116 147 2e-35
07291 137 2e-32
17300 124 6e-30
20640 125 9e-29
07940 119 9e-27
08294 117 2e-26
18996 111 2e-24
14477 108 9e-24
17253 97 5e-20
22005 96 8e-20
18921 96 9e-20
17637 90 5e-18
13305 87 3e-17
00300 87 4e-17
01718 87 4e-17
19301 83 6e-16
12721 78 2e-14
14420 75 2e-13
13592 73 5e-13
27546 70 6e-12
30755 69 1e-11
00715 68 2e-11
13066 67 3e-11
31885 67 4e-11
07833 66 8e-11
09606 65 2e-10
14126 65 2e-10
01060 63 7e-10
19094 62 2e-09
13212 61 2e-09
29581 60 6e-09
01756 59 9e-09
19761 59 1e-08
04591 59 1e-08
03240 57 5e-08
21079 57 5e-08
01707 56 8e-08
18484 55 1e-07
07836 54 3e-07
01966 54 4e-07
26711 51 3e-06
15910 51 3e-06
12672 49 9e-06
25550 49 1e-05
32264 49 1e-05
21433 48 2e-05
28157 46 6e-05
26560 44 3e-04
04138 44 5e-04
01392 42 0.001
12786 41 0.002
07933 40 0.005
03508 40 0.005
37602 39 0.014
38046 38 0.018
18481 37 0.031
11185 37 0.034
02638 36 0.064
00486 35 0.17
26009 35 0.22
16708 34 0.30
15741 34 0.36
27287 34 0.36
27405 34 0.40
21210 33 0.62
25019 32 1.9
32359 31 3.5
22855 30 5.7
>06405
Length = 1965
Score = 221 bits (562), Expect = 1e-57, Method: Compositional matrix adjust.
Identities = 109/275 (39%), Positives = 165/275 (60%), Gaps = 2/275 (0%)
Frame = +1
Query: 431 PSTRDYEIQRERIELGRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFL 490
P +EI+R I + +G GQ+GDV++ ++ VA+KT K T FL
Sbjct: 229 PEPDRWEIERTEIAMKHRLGGGQYGDVYEAMWKRYNK---IVAVKTLKEDTM--ALNDFL 393
Query: 491 QEALTMRQFDHPHIVKLIGVIT-ENPVWIIMELCTLGELRSFLQVRKYSLDLASLILY-A 548
+EA M++ HP++V+L+GV T E P +I+ E G L +L+ + + ++Y A
Sbjct: 394 EEAAIMKEMKHPNLVQLLGVCTREPPFYIVTEFMPHGNLLDYLRSSTREENGPTALMYMA 573
Query: 549 YQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIK 608
Q+++ +AYLE+K F+HRD+AARN LV+ ++ VK+ DFGL+R M+D TY K PIK
Sbjct: 574 TQIASGMAYLETKNFIHRDLAARNCLVADSNMVKVADFGLARLMKDDTYTAHIGAKFPIK 753
Query: 609 WMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNC 668
W APE + F RF++ SD+W FGV +WE+ +G+ P+ GV+ +V +E G R+ PP
Sbjct: 754 WTAPEGLAFNRFSTRSDIWAFGVLLWELATYGMSPYPGVELTEVYHLLERGYRMERPPGT 933
Query: 669 PPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEE 703
P +Y LM KCW +DP RP F E+ L + E+
Sbjct: 934 PADVYILMLKCWQWDPKDRPTFKEIHFLLENMFEK 1038
>21808
Length = 1011
Score = 199 bits (507), Expect = 4e-51, Method: Compositional matrix adjust.
Identities = 98/236 (41%), Positives = 144/236 (61%), Gaps = 1/236 (0%)
Frame = +1
Query: 467 NPALAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITEN-PVWIIMELCTL 525
N VAIKT K+ T D + FL EA M++ HP +++L V T++ P++II EL
Sbjct: 13 NNTTPVAIKTLKSGTMDP--KDFLAEAQIMKKLRHPKLIQLYAVCTQDDPIFIITELMKN 186
Query: 526 GELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGD 585
G L FLQ + L L +LI Q++ +AYLES+ ++HRD+AARN+LVS N+ VK+ D
Sbjct: 187 GSLLEFLQGKGRVLKLPALIDIGAQIACGMAYLESQNYIHRDLAARNILVSDNNTVKIAD 366
Query: 586 FGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQ 645
FGL+R +++ Y + PIKW APE+ N+ RFT SDVW FG+ + E + +G P+
Sbjct: 367 FGLARVIKEDEYEARVGARFPIKWTAPEAANYNRFTIKSDVWSFGILLTETVTYGRVPYP 546
Query: 646 GVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTIL 701
G+ N +V+ ++E+G R+P PP CP LY +M +CW + RP + IL
Sbjct: 547 GMTNAEVLHQVEHGYRMPCPPGCPKPLYDIMLECWRKEEMERPHLRNPAMEAGGIL 714
>11780
Length = 1713
Score = 121 bits (304), Expect(2) = 1e-44, Method: Compositional matrix adjust.
Identities = 69/179 (38%), Positives = 102/179 (56%), Gaps = 1/179 (0%)
Frame = +3
Query: 438 IQRERIELGRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTMR 497
I + +E+G IG+G FGDV++G+Y VAIK K+ D + FLQEA M
Sbjct: 588 IAXQDLEIGEAIGKGDFGDVYKGMYRGQ-----PVAIKQLKD--KDRGEQSFLQEASVMT 746
Query: 498 QFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVRKYS-LDLASLILYAYQLSTALA 556
H ++V+LIGV+ ++++ E G L +L+ R S + I +A A+
Sbjct: 747 SLRHDNLVRLIGVVLGETIFLVTEFMGKGNLVEYLRSRGRSVITKKDQINFATDTCAAME 926
Query: 557 YLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESI 615
YLESKR VHRD+AARNVLV + K+ DFGL+++ + + + K PIKW APE++
Sbjct: 927 YLESKRLVHRDLAARNVLVHDDGKAKVSDFGLAKFGD----FSQTSVKFPIKWTAPEAL 1091
Score = 77.8 bits (190), Expect(2) = 1e-44, Method: Compositional matrix adjust.
Identities = 33/81 (40%), Positives = 49/81 (60%)
Frame = +1
Query: 619 RFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTK 678
+FTS SD+W FG+ +WEI G P+ + DV+ +E G R+ P CPP +YS+M +
Sbjct: 1102 KFTSKSDMWSFGILLWEIYSFGRVPYPRIPLTDVVMHVERGYRMEAPEGCPPEIYSIMKQ 1281
Query: 679 CWAYDPSRRPRFTELKAQLST 699
W DP+ RP F + A+L+
Sbjct: 1282 AWELDPNERPTFKSVLARLNN 1344
>09007
Length = 1440
Score = 176 bits (445), Expect = 6e-44, Method: Compositional matrix adjust.
Identities = 94/274 (34%), Positives = 146/274 (53%), Gaps = 11/274 (4%)
Frame = -1
Query: 438 IQRERIELGRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTMR 497
I ++ + L + +G+G FG V Q I+ + + VA+K ++FL+E M+
Sbjct: 888 ISKDCVALSKSLGQGHFGTVRQAIWTAESGEKVQVAVKCLSKDKIHKDGQEFLKETAIMQ 709
Query: 498 QFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVRK-----YSLDLASLILYAYQLS 552
DH +IV++ GV+ +N IM + L +RS L+ K + L ++ Q+
Sbjct: 708 MLDHENIVRVYGVVMDNGA-DIMLVTELAPMRSLLECVKEVSARVDFSVPRLCDFSQQVC 532
Query: 553 TALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKL----PIK 608
++YLESKR VHRD+AARN+L+ S VK+ D G+S + Y S+ + +
Sbjct: 531 DGMSYLESKRLVHRDLAARNILLFSKSKVKISDVGVSGALGAGKEYYQSQQTIHLQNAVA 352
Query: 609 WMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIE--NGERLPMPP 666
W APES F+SASDVW FGV +WE HG +P+ G+ ++ ++ +RL P
Sbjct: 351 WCAPESFRNLCFSSASDVWAFGVLLWEFFTHGFQPWAGLNGQQIMEAVDAPQSQRLEQPD 172
Query: 667 NCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTI 700
CP Y++M KCW +P RRP F++L L I
Sbjct: 171 LCPKEYYAVMLKCWEQEPQRRPTFSQLFLTLPQI 70
>04852
Length = 1462
Score = 162 bits (410), Expect = 7e-40, Method: Compositional matrix adjust.
Identities = 88/263 (33%), Positives = 141/263 (53%), Gaps = 30/263 (11%)
Frame = +1
Query: 469 ALAVAIKTCKNCTSDSVREKFLQEALTMRQF----DHPHIVKLIGVITEN-PVWIIMELC 523
A VA+K ++ + + F+QE M+ H +IV +G T+ P+W+I+E
Sbjct: 19 ASTVAVKMLRDIVTAVEEQDFVQELQVMKAVKKMGSHINIVNFLGCCTQGGPLWVIVEFA 198
Query: 524 TLGELRSFLQ-----VRKYS-------------------LDLASLILYAYQLSTALAYLE 559
G LR FL+ + Y + +L+ YA+Q++ + +L
Sbjct: 199 KNGNLRDFLESCRDGINGYGKFVSPQDPGWYTKTPGGHVIRRKNLLSYAFQIARGMEFLA 378
Query: 560 SKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRR 619
S++ +HRD+AARNVLV+ +K+ DFGLSR Y K S G+LP+KWMAPE++ R
Sbjct: 379 SRKCIHRDLAARNVLVTEEHVLKIADFGLSR--TGDYYKKRSGGRLPVKWMAPEALFDMR 552
Query: 620 FTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGR-IENGERLPMPPNCPPTLYSLMTK 678
+T+ SDVW FGV +WEI G P+ + N ++ + +++ R+P P LY++M +
Sbjct: 553 YTTKSDVWSFGVVLWEIFSLGGMPYASIPNEELYSKLLDDAYRMPRPELASGNLYAIMER 732
Query: 679 CWAYDPSRRPRFTELKAQLSTIL 701
CW PS RP F++L + +L
Sbjct: 733 CWLNRPSDRPEFSQLVGHIDRLL 801
>14116
Length = 1017
Score = 147 bits (371), Expect = 2e-35, Method: Compositional matrix adjust.
Identities = 85/259 (32%), Positives = 140/259 (54%), Gaps = 19/259 (7%)
Frame = -1
Query: 401 EKQGMRTHAVSVSETDDYAEIID------------EEDTYTMPSTRDYEIQRERIELGRC 448
+ G RT+ + E +DY +D +ED + I RE + +G
Sbjct: 789 DSNGTRTYNLEARE-NDYFNRLDVQGAEAMPLLHIDEDMMKLIENESLLIDREFLTMGEE 613
Query: 449 IGEGQFGDVHQGIYMSPENPA-LAVAIKTCKNCTSDSVR-EKFLQEALTMRQFDHPHIVK 506
IG+G FG V +G PE + VA+KT N + + FLQEAL M+ F H +++
Sbjct: 612 IGKGNFGCVKRGFLTLPEQKGDILVAVKTLHNNNPREIELQSFLQEALIMKDFHHSNVLT 433
Query: 507 LIGV---ITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRF 563
LIG+ + + P+ +++ G+L ++++ ++ + LI+Y ++ + YL +F
Sbjct: 432 LIGICLNLDDMPL-VVLPFMKHGDLLTYIRDDQHQPTIKDLIMYGVDIARGMDYLAGLKF 256
Query: 564 VHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKA--SKGKLPIKWMAPESINFRRFT 621
VHRD+AARN ++ + VK+ DFGL+R + + YY + K KLP+KWMA ES+ +
Sbjct: 255 VHRDLAARNCMLDEDFHVKVADFGLARDIYEKEYYSSENKKAKLPVKWMALESLEKGNYD 76
Query: 622 SASDVWMFGVCMWEILMHG 640
S +DVW +GV +WE+L G
Sbjct: 75 SKTDVWSYGVVLWELLTRG 19
>07291
Length = 833
Score = 137 bits (346), Expect = 2e-32, Method: Compositional matrix adjust.
Identities = 62/164 (37%), Positives = 101/164 (61%), Gaps = 2/164 (1%)
Frame = +1
Query: 539 LDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYY 598
L + L+ + Q++ +AYL+ + VHR++AARN +V+ + ++L D+G++ + +YY
Sbjct: 40 LTVVQLLDFGRQIADGMAYLQEVKVVHRNLAARNCIVTEDGRLQLSDYGVTGSLFPQSYY 219
Query: 599 KA--SKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRI 656
A S + +KWMAPE+I+ F+S SDVW FGV +WE+L G+ P+ V+N+ ++ +
Sbjct: 220 TADDSPARDLVKWMAPETIDNFHFSSKSDVWAFGVVLWELLTRGITPYPDVENSSLLPYL 399
Query: 657 ENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTI 700
+ G R+ P P +Y +MT CW P +RP F EL QL T
Sbjct: 400 KEGHRMKKPKQSPEPVYEMMTACWNESPEQRPDFAELNDQLKTF 531
>17300
Length = 480
Score = 124 bits (310), Expect(2) = 6e-30, Method: Compositional matrix adjust.
Identities = 56/117 (47%), Positives = 78/117 (66%), Gaps = 3/117 (2%)
Frame = +1
Query: 551 LSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTY---YKASKGKLPI 607
+S+ + L +VHRD+AARN+LV+ K+ DFGLSR +E T Y GK+P+
Sbjct: 1 ISSGMGXLADMGYVHRDLAARNILVNEILVCKVADFGLSREIESDTTEGAYTTKGGKIPV 180
Query: 608 KWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPM 664
+W APE+I +R+FTSASDVW FGV MWE++ +G +P+ N DVI +E G RLP+
Sbjct: 181 RWTAPEAIAYRKFTSASDVWSFGVVMWEVMSYGERPYWNWSNQDVIKAVEKGYRLPL 351
Score = 26.6 bits (57), Expect(2) = 6e-30, Method: Compositional matrix adjust.
Identities = 10/35 (28%), Positives = 18/35 (51%)
Frame = +2
Query: 667 NCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTIL 701
+CP L+ LM W + S RP+ + + L ++
Sbjct: 356 DCPEALHQLMLDAWQKERSHRPKMSMVVKTLDKLI 460
>20640
Length = 1492
Score = 125 bits (314), Expect = 9e-29, Method: Compositional matrix adjust.
Identities = 55/139 (39%), Positives = 85/139 (61%), Gaps = 1/139 (0%)
Frame = +1
Query: 563 FVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASK-GKLPIKWMAPESINFRRFT 621
+VHRD+A RN LV + VK+ DFGL+R + YY+ S+ +PI+WM E+I + +F+
Sbjct: 7 YVHRDLATRNCLVGHDLVVKISDFGLARSVHSVDYYRGSEHDAIPIRWMPLEAILYNKFS 186
Query: 622 SASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWA 681
+ SDVW FGV +WEI ++P+ G+ + +V+ ++ G+ L P PP +Y LM +CW
Sbjct: 187 TQSDVWSFGVVLWEIFAFALQPYYGLTHEEVVRFVKEGKVLACPERTPPPMYELMKQCWH 366
Query: 682 YDPSRRPRFTELKAQLSTI 700
P+ RP F L L +
Sbjct: 367 RRPATRPSFHTLHKTLENM 423
>07940
Length = 1336
Score = 119 bits (297), Expect = 9e-27, Method: Compositional matrix adjust.
Identities = 54/111 (48%), Positives = 77/111 (69%), Gaps = 1/111 (0%)
Frame = -3
Query: 544 LILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYY-KASK 602
LI YAYQ++ + YL SK+ +HRD+AARNVLV+ +K+ DFGL+R ++ YY K +
Sbjct: 341 LISYAYQVARGMEYLASKQCIHRDLAARNVLVAEEYVLKIADFGLTRNLQQFDYYRKTTD 162
Query: 603 GKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVI 653
G+LP+KWMAPE++ R++TS SDVW +GV +WEI G P+ V D+
Sbjct: 161 GRLPVKWMAPEALFDRKYTSKSDVWSYGVLLWEIFTLGGNPYPSVPVEDLF 9
Score = 58.5 bits (140), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 37/114 (32%), Positives = 59/114 (51%), Gaps = 4/114 (3%)
Frame = -3
Query: 424 EEDTYTMPSTRDYEIQRERIELGRCIGEGQFGDVHQGIYMS--PENPALAVAIKTCKNCT 481
E Y +P +E RER+ LG +GEG FG V +G M +N ++ VA+K K
Sbjct: 893 EVSEYDLPLDAKWEFPRERLVLGDRLGEGAFGLVMKGEAMGIFKDNNSVTVAVKMLKEDA 714
Query: 482 SDSVREKFLQEALTMRQF-DHPHIVKLIGVITE-NPVWIIMELCTLGELRSFLQ 533
+D ++E M+ H +I+ L+G T+ +++I+E G LR FL+
Sbjct: 713 TDREMMDLIREMEMMKVIGKHKNIINLLGCCTQRGALYVIVEFAPHGNLRDFLK 552
>08294
Length = 1849
Score = 117 bits (294), Expect = 2e-26, Method: Compositional matrix adjust.
Identities = 67/209 (32%), Positives = 113/209 (54%), Gaps = 12/209 (5%)
Frame = +2
Query: 502 PHIVKLIGVITE-NPVWIIMELCTLGELRSFL-----------QVRKYSLDLASLILYAY 549
P+IV +GV E P ++I E C G+L+ FL R +L L+ +
Sbjct: 887 PNIVHFMGVCREAEPHFLITEYCDWGDLKQFLLATRNDNGRGRGTRVPALALSQKLGMGQ 1066
Query: 550 QLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKW 609
Q++ + L ++ VH D+AARNVL++S +K+ LS + S YY + +P++W
Sbjct: 1067 QVAAGMEALSNQGLVHGDLAARNVLLTSRMQLKVARPALSGDVYASEYYPLHQRLVPLRW 1246
Query: 610 MAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCP 669
+ PE + T+ DVW FGV +WE+L P++ + + +V+ +++ + P+ P
Sbjct: 1247 LPPEGVLEDSATTCGDVWAFGVFLWEVLQLADLPYRLMSDEEVLRSLQHSQAALDSPDAP 1426
Query: 670 PTLYSLMTKCWAYDPSRRPRFTELKAQLS 698
P L SL+ +C A PS+RP F+E+ + LS
Sbjct: 1427 PALLSLLQRCTAQQPSQRPPFSEICSVLS 1513
>18996
Length = 491
Score = 111 bits (277), Expect = 2e-24, Method: Compositional matrix adjust.
Identities = 56/136 (41%), Positives = 82/136 (60%), Gaps = 6/136 (4%)
Frame = +2
Query: 564 VHRDIAARNVLVSSNDCVKLGDFGLSRYME-DSTYYKASKGKLPIKWMAPESINFRRFTS 622
+HRD+AARN+LV + CVK+ DFGL+++ D YY S+ +PIKW +PE+I +F+S
Sbjct: 2 IHRDLAARNILVDRS-CVKISDFGLAQFANADGYYYGISQRDIPIKWYSPEAIETCKFSS 178
Query: 623 ASDVWMFGVCMWEILMHG----VKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYS-LMT 677
SDVW +GV ++E+ G + P + + + R+ GERLP P C +YS LM
Sbjct: 179 YSDVWSYGVTLFEMFSRGEIPNLLPGHDLTQEEFLNRLRKGERLPKPELCSDFVYSELMR 358
Query: 678 KCWAYDPSRRPRFTEL 693
CW P RP F ++
Sbjct: 359 PCWHEMPKSRPTFHQI 406
>14477
Length = 493
Score = 108 bits (271), Expect = 9e-24, Method: Compositional matrix adjust.
Identities = 62/169 (36%), Positives = 102/169 (60%), Gaps = 2/169 (1%)
Frame = -1
Query: 437 EIQRERIELGRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSD-SVREKFLQEALT 495
+IQ + ++LG G FG V +G+ ++ + VAIK KN D SV+ + ++EA
Sbjct: 490 QIQMDELKLG----AGNFGSVMKGVC-RLDDREIPVAIKVLKNADLDPSVQSELIKEAEV 326
Query: 496 MRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTAL 555
M++ DH HIV+LIG+ + +++EL LG L FL K+ L L +++ +Q+S +
Sbjct: 325 MKKMDHMHIVRLIGLCEGETMMLVLELAKLGPLNKFLPKNKH-LPLWNILELMWQVSQGM 149
Query: 556 AYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYM-EDSTYYKASKG 603
YLE+ +FVHRD+AARN+L+ K+ DFG+S+ + ++ YY A +
Sbjct: 148 EYLEANKFVHRDLAARNILLCDEHFAKISDFGMSKTLSRENNYYMAQEA 2
>17253
Length = 483
Score = 96.7 bits (239), Expect = 5e-20, Method: Composition-based stats.
Identities = 55/153 (35%), Positives = 88/153 (57%), Gaps = 15/153 (9%)
Frame = -1
Query: 472 VAIKTCKNCTSDSVREKFLQEALTMRQFD-HPHIVKLIGVIT-ENPVWIIMELCTLGELR 529
VA+KT +D+ + +FL+E MR+ HP++V +G T +P I+ME C G+L
Sbjct: 459 VAVKTHNEAATDAEKSEFLRELSIMRKLPRHPNVVSFMGCCTMSDPALILMEFCCHGDLL 280
Query: 530 SFLQVRK---------YSLDLASLILYAYQLSTA--LAYLESKRFVHRDIAARNVLVSSN 578
SFL+ R+ + DL + +++ L A +A++ + + VHRD+AARNVL+S
Sbjct: 279 SFLRKRRPDRTVFLTSTANDLTARDFFSFALHVARGMAHVANNKIVHRDVAARNVLISER 100
Query: 579 DCVKLGDFGLSRYMEDS--TYYKASKGKLPIKW 609
+ K+ DFGLSR + D Y S+ LP++W
Sbjct: 99 NVCKVSDFGLSRRVGDQNDVYEIVSRRPLPLRW 1
>22005
Length = 873
Score = 95.9 bits (237), Expect = 8e-20, Method: Compositional matrix adjust.
Identities = 78/246 (31%), Positives = 118/246 (47%), Gaps = 55/246 (22%)
Frame = +1
Query: 447 RCIGEGQFGDVHQGIYMS---------PEN-PALAVAIKTCKNCTSDSVREKFLQEALTM 496
R IG+G FG V + ++ PE P L K K S+ ++ F +EA M
Sbjct: 1 RDIGQGAFGRVSKLKFLGLASLVGELIPEKRP*LL*--KMLKEDASEDLQSDFEREASLM 174
Query: 497 RQFDHPHIVKLIGVIT-ENPVWIIMELCTLGELRSFLQV---RKYSL------------- 539
FDHP+IVKL+GV P+ ++ E + G+L FL++ Y+L
Sbjct: 175 ADFDHPNIVKLLGVCAIGKPMCLLFEFMSKGDLNDFLRLCSPENYNLPVSRSQNLVVDLE 354
Query: 540 ---------------------DLASLI-----LY-AYQLSTALAYLESKRFVHRDIAARN 572
D + ++ LY + Q+S +AYL K +VHRD+A R
Sbjct: 355 DGLRVEVEAEECEKDTQSEDRDCSGMLXTKDQLYISQQISAGMAYLAQKDYVHRDLATRT 534
Query: 573 VLVSSNDCVKLGDFGLSRYMEDSTYYKAS-KGKLPIKWMAPESINFRRFTSASDVWMFGV 631
V + + DFGL+R + YY+ S + +PI+WM E+I + +F++ SDVW FGV
Sbjct: 535 VXSRTT*-S*ISDFGLARSVHSVDYYRGSEQDAIPIRWMPLEAILYSKFSTQSDVWSFGV 711
Query: 632 CMWEIL 637
+WEIL
Sbjct: 712 VLWEIL 729
>18921
Length = 697
Score = 95.5 bits (236), Expect = 9e-20, Method: Compositional matrix adjust.
Identities = 68/232 (29%), Positives = 114/232 (49%), Gaps = 4/232 (1%)
Frame = +2
Query: 445 LGRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHI 504
LG+ +GEG +G V + ++ LA+ K D+ ++ ++E M+Q D +I
Sbjct: 44 LGK-LGEGSYGSVFKSLHKE-TGQVLAI-----KQVPVDTDLQEIIKEISIMQQCDSKYI 202
Query: 505 VKLIGVITENP-VWIIMELCTLGELRSFLQVRKYSL---DLASLILYAYQLSTALAYLES 560
VK G +N +WI+ME C G + +++R +L ++A+++ Y + L YL S
Sbjct: 203 VKYYGSYFKNTDLWIVMEYCGAGSVSDIMRLRNKTLVEREIATILYYTLK---GLXYLHS 373
Query: 561 KRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRF 620
+R +HRDI A N+L+++ KL DFG++ + D+ + + P WMAPE I +
Sbjct: 374 RRKIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTPY-WMAPEVIQEIGY 550
Query: 621 TSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTL 672
+D+W G+ E + G P I G+ P N PP L
Sbjct: 551 DCVADIWSLGITALE-MAEGKPPVMETS-------IL*GQSS*FPTNAPPPL 682
>17637
Length = 447
Score = 89.7 bits (221), Expect = 5e-18, Method: Compositional matrix adjust.
Identities = 46/128 (35%), Positives = 70/128 (54%), Gaps = 1/128 (0%)
Frame = +1
Query: 572 NVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKL-PIKWMAPESINFRRFTSASDVWMFG 630
N ++ VKL D LSR + Y G+ PIKW++ E++ + SDVW FG
Sbjct: 1 NCVIDDQLRVKLTDSALSRDLFSGDYNCLGDGEYRPIKWLSLEALQKSHYNEGSDVWSFG 180
Query: 631 VCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRF 690
V MWE+ G P+ + ++ +++G RL P NCP L+++M CWA P+ RP F
Sbjct: 181 VLMWEMCTLGKLPYAEIDPYEMEHYLKDGYRLAQPFNCPDELFTIMAYCWASMPAERPSF 360
Query: 691 TELKAQLS 698
++L+ LS
Sbjct: 361 SQLQICLS 384
>13305
Length = 549
Score = 87.4 bits (215), Expect = 3e-17, Method: Composition-based stats.
Identities = 37/100 (37%), Positives = 57/100 (57%)
Frame = +2
Query: 604 KLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLP 663
++PI+WMA ES+ +T+ SDVW FGV +WEI G P+ + +++G RL
Sbjct: 8 RVPIRWMAVESLFNNTYTTQSDVWSFGVVLWEIFTLGGTPYSSTDTQQLFAFLKDGYRLK 187
Query: 664 MPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEE 703
P C Y++M +CW + RRP F EL +L +L++
Sbjct: 188 RPKLCDQNTYAMMLQCWNENAQRRPTFPELCGRLQRMLDD 307
>00300
Length = 2318
Score = 87.0 bits (214), Expect = 4e-17, Method: Compositional matrix adjust.
Identities = 74/276 (26%), Positives = 122/276 (44%), Gaps = 13/276 (4%)
Frame = -1
Query: 431 PSTRDYEIQRERIEL----GRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSD--S 484
P DY I R+ G IGEGQFG V+ + MS +A+K K +D
Sbjct: 1700 PREPDYRINVRRVNFRWQRGNKIGEGQFGKVYTAVNMST---GELMALKEMKFQPNDLQQ 1530
Query: 485 VREKFLQEALTMRQFDHPHIVKLIGV-ITENPVWIIMELCTLGELRSFLQVRKYSLDLAS 543
+RE E H ++VK GV + ++ + + ME C G + + K L
Sbjct: 1529 LRE-MCDEIKIFEGIQHENLVKYYGVEVHKDEMLMFMEYCDTGTIE---EAAKMGLPEYL 1362
Query: 544 LILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKG 603
+ Y ++ A+ +L VHRDI N+ ++SN VKLGDFG S ++ T
Sbjct: 1361 IRRYTREIVLAVNHLHENSIVHRDIKGANIFLTSNGHVKLGDFGCSVKLKSHTTMPGEFH 1182
Query: 604 KL--PIKWMAPESINFRR---FTSASDVWMFGVCMWEILMHGVKPFQGVKNN-DVIGRIE 657
L +MAPE + A+D+W G + E+ G +P+ + NN ++ ++
Sbjct: 1181 NLVGTTAYMAPEVFTQNDQGGYGRAADIWSLGCVVIEMAT-GKRPWHDLDNNYQIMYKVG 1005
Query: 658 NGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTEL 693
G + +P + + +DP++R ++L
Sbjct: 1004 IGHKPAVPDSLSVEGKHFLDLIMCHDPAQRALASQL 897
>01718
Length = 959
Score = 87.0 bits (214), Expect = 4e-17, Method: Compositional matrix adjust.
Identities = 73/271 (26%), Positives = 111/271 (40%), Gaps = 14/271 (5%)
Frame = +3
Query: 449 IGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLI 508
IG G F +V + + + + K T S R L+E + + H +I++ +
Sbjct: 171 IGAGFFSEVFKVTH------RITGQVMALKMNTMTSNRHNMLREVQLLNRLQHANILRFM 332
Query: 509 GV-ITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRD 567
GV + E + + E G L L+ + L I L+ L YL S RF+HRD
Sbjct: 333 GVCVHEGQLHALTEYIPSGNLEQLLEKKDEELPWTQRIQLTLGLARGLDYLHSTRFIHRD 512
Query: 568 IAARNVLVSSNDC----VKLGDFGLSRYMEDSTYYKASKGKLPI----KWMAPESINFRR 619
+ ++N+L+ D + DFGL+ + D K KLP WMAPE +N
Sbjct: 513 LTSKNILIRREDNHGYHAVIADFGLATKIPDPL----DKEKLPTVGSPYWMAPEVLNGHF 680
Query: 620 FTSASDVWMFGVCMWEILMH-----GVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYS 674
+ +D++ G+ M EI + P D + E M CP
Sbjct: 681 YNERADLFSVGIIMCEITARIPADPDIMPRMNNFGVDYVALSE------MISYCPLDYLQ 842
Query: 675 LMTKCWAYDPSRRPRFTELKAQLSTILEEEK 705
L KC DP +RPR E+ L I + K
Sbjct: 843 LAFKCCQVDPQKRPRGVEIIEWLEKIFKNLK 935
>19301
Length = 712
Score = 82.8 bits (203), Expect = 6e-16, Method: Compositional matrix adjust.
Identities = 54/170 (31%), Positives = 87/170 (51%), Gaps = 1/170 (0%)
Frame = +2
Query: 421 IIDEEDTYTMPSTRDYEIQRERIELGRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNC 480
II + + D+EI E I +G G G V G + E VA+K ++
Sbjct: 245 IIGKAAAAELKQQDDWEIPFESITDLEWLGSGAQGAVFLGKLCAEE-----VAVKKVRDI 409
Query: 481 TSDSVREKFLQEALTMRQFDHPHIVKLIGVITENPVW-IIMELCTLGELRSFLQVRKYSL 539
+R +R+ +HP+I+ GV T+ P + IIME C G+L L+ K +
Sbjct: 410 KETDIR--------NLRKLNHPNIISFKGVCTQAPCYCIIMEYCPYGQLYEVLRDGK-EI 562
Query: 540 DLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLS 589
A ++ ++ Q+++ + YL S + +HRD+ + NVLV+ ND VK+ DFG S
Sbjct: 563 PPALVLDWSKQIASGMNYLHSHKIIHRDLKSPNVLVAKNDVVKISDFGTS 712
>12721
Length = 821
Score = 77.8 bits (190), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 66/247 (26%), Positives = 103/247 (41%), Gaps = 8/247 (3%)
Frame = +1
Query: 449 IGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLI 508
IGEG G V I S + +AV + RE E + MR + HP+IV++
Sbjct: 112 IGEGSTGIV--CIATSRDGRQMAVKKMDLRK---QQRRELLFNEVVVMRDYHHPNIVEMY 276
Query: 509 G-VITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRD 567
+ + +W++ME G L V +D + ALA+L + +HRD
Sbjct: 277 NSYLVNDELWVVMEFMEGGALTDI--VTNNRMDEVQIATVCRACLKALAFLHANGVIHRD 450
Query: 568 IAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVW 627
I + ++L+S + VKL DFG + + S P WMAPE I+ + D+W
Sbjct: 451 IKSDSILLSHDGKVKLXDFGFCAQVTQDLQKRKSLVGTPY-WMAPEVISRLPYGPEVDIW 627
Query: 628 MFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPP-------NCPPTLYSLMTKCW 680
G+ + E ++ PF + RI + MPP P L + +
Sbjct: 628 SLGIMVME-MIDAEPPFFNEPPLQAMRRIRD-----MPPPKLRNTHKISPRLQGFIDRML 789
Query: 681 AYDPSRR 687
DP +R
Sbjct: 790 VRDPHQR 810
>14420
Length = 528
Score = 74.7 bits (182), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 45/167 (26%), Positives = 78/167 (46%), Gaps = 1/167 (0%)
Frame = +2
Query: 479 NCTSDSVREKFLQEALTMRQFDHPHIVK-LIGVITENPVWIIMELCTLGELRSFLQVRKY 537
N + +E + E L MR+ +P+IV L + +W++ME G L V +
Sbjct: 11 NLSQQPKKELIINEILVMRENQNPNIVNYLDSYLVGEELWVVMEFLAGGSLTDV--VTET 184
Query: 538 SLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTY 597
+D + + AL +L + +HRDI + N+L+ + VKL DFG +
Sbjct: 185 CMDEGQIAAVCRECLQALEFLHENQVIHRDIKSDNILLGMDGSVKLTDFGFCAQLSPEQS 364
Query: 598 YKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPF 644
+++ P WMAPE + +++ D+W GV E ++ G P+
Sbjct: 365 KRSTMVGTP-YWMAPEVVTRKQYGPTVDIWSLGVMCIE-MIEGEPPY 499
>13592
Length = 980
Score = 73.2 bits (178), Expect = 5e-13, Method: Compositional matrix adjust.
Identities = 67/257 (26%), Positives = 119/257 (46%), Gaps = 9/257 (3%)
Frame = +2
Query: 449 IGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTMRQ-FDHPHIVKL 507
IG+G+FG V+ + N +A+K ++ K + E L + + H ++V+
Sbjct: 8 IGQGRFGKVYTAV---NNNTGELMAMKEIAIQPGETRALKNVAEELKILEGIKHKNLVRY 178
Query: 508 IGV-ITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHR 566
G+ + + I MELC+ G L S +++ L A + QL + +A L VHR
Sbjct: 179 YGIEVHREELLIFMELCSEGTLESLVELTG-GLPEALSRRFTAQLLSGVAELHKHGIVHR 355
Query: 567 DIAARNV-LVSSNDCVKLGDFGLSRYMEDSTYYKAS-KGKLPIK-WMAPE---SINFRRF 620
DI N+ LV ++ +KLGDFG + ++ T +G + + +MAPE N
Sbjct: 356 DIKTANIFLVDGSNSLKLGDFGSAVKIQAHTTVPGELQGYVGTQAYMAPEVFTKTNSDGH 535
Query: 621 TSASDVWMFGVCMWEILMHGVKPFQGVKNN-DVIGRIENGERLPMPPNCPPTLYSLMTKC 679
+D+W G + E + G +P+ +N ++ ++ GE+ P + + + C
Sbjct: 536 GRLADIWSVGCVVVE-MASGKRPWAQFDSNFQIMFKVGMGEKPQAPESLSQEGHDFIDHC 712
Query: 680 WAYDPSRRPRFTELKAQ 696
+DP +R EL Q
Sbjct: 713 LQHDPKQRLSAIELLEQ 763
>27546
Length = 426
Score = 69.7 bits (169), Expect = 6e-12, Method: Composition-based stats.
Identities = 35/114 (30%), Positives = 65/114 (57%), Gaps = 1/114 (0%)
Frame = -1
Query: 483 DSVREKFLQEALTMRQFDHPHIVKLIGVITENP-VWIIMELCTLGELRSFLQVRKYSLDL 541
D V++ F +E + + DHP+I+++ ++ P ++I M G++ S ++ + +D
Sbjct: 357 DFVKKFFPRELEILTRLDHPNIIQIHSILQRGPKIFIFMRYAEKGDMLSHIK-KTGPIDE 181
Query: 542 ASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDS 595
A ++ +Q++ AL YL S HRD+ N+L+S VK+ DFG +RY D+
Sbjct: 180 AQTKVWFFQMAKALQYLHSHDIAHRDLKCENILLSKRLNVKIADFGFARYCRDA 19
>30755
Length = 1137
Score = 68.9 bits (167), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 44/143 (30%), Positives = 76/143 (53%), Gaps = 1/143 (0%)
Frame = +2
Query: 546 LYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKL 605
Y ++ +AL YL S+ ++RD+ N+L+ + +K+ DFGL + ED TY + +K
Sbjct: 44 FYGAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCK--EDITYGRTTKTFC 217
Query: 606 PI-KWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPM 664
+++APE ++ + A D W GV M+E++ G PF +++DV+ + E +
Sbjct: 218 GTPEYLAPEVLDDNDYGRAVDWWGTGVVMYEMIC-GRLPFYN-RDHDVLFTLILVEDVKF 391
Query: 665 PPNCPPTLYSLMTKCWAYDPSRR 687
P N SL++ A DP R
Sbjct: 392 PRNITDEAKSLLSGLLAKDPRNR 460
>00715
Length = 1788
Score = 67.8 bits (164), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 59/253 (23%), Positives = 110/253 (43%), Gaps = 34/253 (13%)
Frame = +1
Query: 470 LAVAIKTCKNCTSDSVREKFLQEALTMR-QFDHPHIVKLIGVIT----ENPVWIIMELCT 524
+AV I ++ ++R+ + E L R H ++V ++G + E+ W+ ME
Sbjct: 7 VAVKIYHKRSSNPRALRQSYSNELLAFRCGLRHVNVVSILGATSLHRFEDGAWLAMEYVG 186
Query: 525 LGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLG 584
L++ L + +D + + A Q++ L YL S VH D+ N L++ + +++
Sbjct: 187 PLNLQTILNDHQQDIDSSMRLSLALQMARGLHYLHSINIVHLDLKPANCLLTRDLKLRIA 366
Query: 585 DFGLSRYM-------------------EDSTYYKASKGKLP--IKWMAPESINFRRFTSA 623
DFG + E + A K +L + + APE + + +
Sbjct: 367 DFGCCHQLTPTGLDMGEREGGMAGNELELTPVQGAWKNELAGTLAYRAPELLKGLQPSVR 546
Query: 624 SDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPT--------LYSL 675
SDV+ G+ +W++ P++GV + V+ ++ + + P PP P T L
Sbjct: 547 SDVYSLGITLWQMCTRQ-GPYEGVPAHAVVYQVVSKDLRPCPP--PSTEDDPFEVMFRDL 717
Query: 676 MTKCWAYDPSRRP 688
T+CWA RP
Sbjct: 718 YTQCWARRVEDRP 756
>13066
Length = 551
Score = 67.0 bits (162), Expect = 3e-11, Method: Compositional matrix adjust.
Identities = 49/174 (28%), Positives = 82/174 (47%), Gaps = 10/174 (5%)
Frame = +3
Query: 467 NPALAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITENPV-WIIMELCTL 525
N LA I + D V + F +E + + DHP+I+++ ++ P +I M
Sbjct: 51 NIKLACKIIDKEKAPVDFVEKFFPRELDLLTKLDHPYIIQIHSILQRXPKNFIFMRFAER 230
Query: 526 GELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGD 585
G+L +++Q + + + I + YQ++TAL YL S HRD+ N+L+SS+ VKL D
Sbjct: 231 GDLLTYIQEVGFVKEKQAKIWF-YQMTTALNYLHSYDVAHRDLKCENILLSSHFNVKLAD 407
Query: 586 FGLS---------RYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFG 630
FG + +YM + A+ I + AP + +D W G
Sbjct: 408 FGFACACITESGEKYMSRTYCGSAAYAAPEIVYGAPYA------PKVADAWSLG 551
>31885
Length = 529
Score = 67.0 bits (162), Expect = 4e-11, Method: Compositional matrix adjust.
Identities = 46/148 (31%), Positives = 77/148 (52%), Gaps = 6/148 (4%)
Frame = -2
Query: 496 MRQFDHPHIVKL-IGVITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTA 554
+ + DHP +V L E ++++++L G+LR +Q ++ S + Y QL+
Sbjct: 510 LTRLDHPFLVNLWYAFQDEEDLFMVVDLFLGGDLRYHMQ-QEVSFREDCVKFYLCQLALV 334
Query: 555 LAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPE- 613
L YL S++ VHRDI N+L+ + DF ++ +ED ++ G P +MAPE
Sbjct: 333 LDYLRSQKIVHRDIKPDNILLDEQGHCHVTDFNIATQLEDDELATSTSGTRP--YMAPEV 160
Query: 614 ---SINFRR-FTSASDVWMFGVCMWEIL 637
+IN RR + D W GV ++E+L
Sbjct: 159 YGVAINERRGYGFPVDWWSLGVSLFELL 76
>07833
Length = 1504
Score = 65.9 bits (159), Expect = 8e-11, Method: Compositional matrix adjust.
Identities = 53/217 (24%), Positives = 99/217 (45%), Gaps = 7/217 (3%)
Frame = -3
Query: 481 TSDSVREKFLQEALTMRQFDHPHIVKLIGVITENP-VWIIMELCTLGELRSFLQVRK-YS 538
+ + F++E +R F+HP+++ ++ + P + +I + G L + L
Sbjct: 1502 VTKRITRDFMEEFPRLRIFNHPNVLPVLACCNQPPNLVLISQFMPFGSLYNTLHGESGIV 1323
Query: 539 LDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYY 598
+D + +A ++ + +L S + N L++S + D M D +
Sbjct: 1322 VDQNQSLRFAMDIARGMEFLHSM-----EPTIPNFLLTSKHVMIDEDLTARINMADYCFS 1158
Query: 599 KASKGKL-PIKWMAPESINFRR---FTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIG 654
KGK+ WMAPE++ R T A+D+W F + MWE+ V PF + + +V
Sbjct: 1157 FHEKGKVYSPAWMAPEALQRRPDDINTRAADMWSFAILMWELETREV-PFAELSSMEVGM 981
Query: 655 RIE-NGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRF 690
++ G R+ +PP + L+ C +P +RPRF
Sbjct: 980 KVALEGLRISIPPGISLHMSRLIKICMNEEPGKRPRF 870
>09606
Length = 1300
Score = 65.1 bits (157), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 68/292 (23%), Positives = 118/292 (40%), Gaps = 37/292 (12%)
Frame = -3
Query: 449 IGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLI 508
+G+G+ +++G N I+ CK R + HP++V+
Sbjct: 1091 LGKGEHSIIYKGRRKGTINFVAIHCIEKCK-------RPEVTNTVRMTHDISHPNVVQFH 933
Query: 509 GVI-TENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRD 567
T N +W+++ELCT G L L + + L S+ + L T L Y+ S + D
Sbjct: 932 EWYETSNHLWLVVELCTGGSLADIL-AQDHHLPETSIRDFGIHLVTGLHYIHSLGILFHD 756
Query: 568 IAARNVLVSSNDCVKLGDFGLSRY----MEDSTYYKASKG-------------KLPIK-- 608
+ VL+ ++ +K DFGLS+ +E+ + A G ++P
Sbjct: 755 LRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQWNIQSAEEMMKQVPTSGS 576
Query: 609 --WMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIEN-------- 658
+MAPE + SD+W G +E + G PF G + ++ N
Sbjct: 575 PTYMAPEVFQGAEPSIMSDLWALGCVFYE-MFSGHPPFLGETYDITKDKVLNKEFPLPKV 399
Query: 659 -GERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTEL------KAQLSTILEE 703
G RL P+ P +L+ D +RR + L + LS++++E
Sbjct: 398 KGSRLSAKPS--PEFLNLLESLLQKDSTRRLSWASLVKHAFWQGGLSSLVKE 249
>14126
Length = 1265
Score = 64.7 bits (156), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 72/296 (24%), Positives = 135/296 (45%), Gaps = 19/296 (6%)
Frame = +3
Query: 390 ALPSIPKLANSEKQGMRTH-AVSVSETDDYAEIIDEEDTYTMPSTRDYEIQRERIELGRC 448
ALP+I ++ +E+ +T AV +T + D + +R + ++ E
Sbjct: 33 ALPTIFRIC*NEESSPKTSPAVRSMKTAISPKGRDGQSESAAKMSRRRDSTEQKYEEVAV 212
Query: 449 IGEGQFGDVHQGIYMSPENPALAVAIKTCK-NCTSDSVREKFLQEALTMRQ---FDHPHI 504
IG G +G V++ + N VA+K + N T + + ++E ++Q ++HP++
Sbjct: 213 IGNGAYGTVYKARDL--RNQGEFVAMKRIRLNNTEEGMPMMAIREISMLKQLEQYEHPNV 386
Query: 505 VKLIGVITENPVWIIMELCTLGELRSFLQVRKYSLDLASLIL--------------YAYQ 550
V+L+ V + N + T E+R L DLA+ + Q
Sbjct: 387 VRLLDV-SHNTI-------TDREIRLNLVFEYIEHDLATYLAKCPSPGLGPDRIKDLMLQ 542
Query: 551 LSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWM 610
L + +L S R VHRD+ +N+L+S + +KL DFGL+R S + + + + +
Sbjct: 543 LLNGVDFLHSNRIVHRDLKPQNLLISKDGRLKLADFGLARIY--SFHMALTTVVVTLWYR 716
Query: 611 APESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPP 666
+PE + + ++ D+W G C++ L F+G D + +I E + +PP
Sbjct: 717 SPEVLMQAEYGTSVDIWSCG-CIFAELFTRRALFKGSSEFDQLKKI--FEVIGLPP 875
>01060
Length = 1800
Score = 62.8 bits (151), Expect = 7e-10, Method: Compositional matrix adjust.
Identities = 48/196 (24%), Positives = 100/196 (51%), Gaps = 6/196 (3%)
Frame = +1
Query: 449 IGEGQFGDVHQGIYMSPENPALAVAIKTCK-NCTSDSVREKFLQEALTMRQFDHPHIVKL 507
IGEG +G V++ + + +A+K + + D V ++E +R+ H +IV L
Sbjct: 97 IGEGTYGVVYKCRHRATGR---KLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTNIVCL 267
Query: 508 IGVITENP-VWIIMELCTLGELRSFLQV--RKYSLDLASLILYAYQLSTALAYLESKRFV 564
VI E+ ++++ E ++ +L+ ++ LD + Y +Q+ T + + +R V
Sbjct: 268 EDVIMEDERLFLVFEFLSM-DLKMYIDKFPEGVVLDRRLVKSYVFQIVTGIXFCHQRRIV 444
Query: 565 HRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWM-APESI-NFRRFTS 622
HRD+ +N+L++ +K+ DFG++R + +A ++ W APE + ++++
Sbjct: 445 HRDLKPQNLLINHTGAIKIADFGMARTF--ALPVRAYTHEVVTLWYRAPEILMGASKYST 618
Query: 623 ASDVWMFGVCMWEILM 638
DVW G ++L+
Sbjct: 619 PVDVWSIGTIFADMLI 666
>19094
Length = 898
Score = 61.6 bits (148), Expect = 2e-09, Method: Composition-based stats.
Identities = 34/114 (29%), Positives = 62/114 (54%), Gaps = 3/114 (2%)
Frame = +1
Query: 526 GELRSFLQVRKYSL---DLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVK 582
G + +++R +L ++A+++ Y + L YL S+R +HRDI A N+L+++ K
Sbjct: 10 GSVSDIMRLRNKTLVEREIATILYYTLK---GL*YLHSRRKIHRDIKAGNILLNNEGHAK 180
Query: 583 LGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEI 636
L DFG++ + D+ + + P WMAPE I + +D+W G+ E+
Sbjct: 181 LADFGVAGQLTDTMAKRNTVIGTPY-WMAPEVIQEIGYDCVADIWSLGITALEM 339
>13212
Length = 1067
Score = 61.2 bits (147), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 51/196 (26%), Positives = 84/196 (42%), Gaps = 18/196 (9%)
Frame = -1
Query: 516 VWIIMELCTL---GELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARN 572
VW I+++ + G L S + + + A + +++ AL +L +HRDI A N
Sbjct: 1067 VWXIVDVFRVLWWGALDSIMVDLEKPMTEAQICYVCHEMCMALDFLHRHHVIHRDIKAGN 888
Query: 573 VLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAP-----ESINFRRFTSASDVW 627
VL++ + VKL DFG+S + + + P WMAP E++ + +D+W
Sbjct: 887 VLLTIDGEVKLADFGVSAKNTQTQQKRDTFIGTPY-WMAPEVVLCETLKDTPYDFKADIW 711
Query: 628 MFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTL----------YSLMT 677
GV + E P + + V+ +I + PPTL +
Sbjct: 710 SLGVTLIE-FAQIEPPNKEMHPMRVLIKIHKSD--------PPTLEKPKKWTKLFKDFIA 558
Query: 678 KCWAYDPSRRPRFTEL 693
KC DP+ RP EL
Sbjct: 557 KCLVKDPNLRPTAAEL 510
>29581
Length = 1278
Score = 59.7 bits (143), Expect = 6e-09, Method: Compositional matrix adjust.
Identities = 49/163 (30%), Positives = 78/163 (47%), Gaps = 8/163 (4%)
Frame = -2
Query: 485 VREKFLQEALTMRQFDHPHIVKLIGVI---TENPVWIIMELCTLGELRSFLQVRKYSLDL 541
VR FL L +R H +IV+L V+ + + ++++ME C +L S L
Sbjct: 1208 VRSTFL---LNLR---HQNIVQLQEVVVGKSLDSLFLVMEYCE-QDLASLLDNMPAPFSE 1050
Query: 542 ASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKAS 601
+ + QL L YL +HRD+ N+L++ CVK+ DFGL+R Y K
Sbjct: 1049 SQVKCIVLQLLKGLRYLHEAFIIHRDLKVSNLLMTDKGCVKIADFGLAR-----NYGKPQ 885
Query: 602 KGKLP----IKWMAPESI-NFRRFTSASDVWMFGVCMWEILMH 639
K P + + APE + + ++A D+W G + E+L H
Sbjct: 884 KPMTPKVVTLWYRAPELLFGSKTHSTAIDMWSAGCILGELLGH 756
>01756
Length = 1858
Score = 59.3 bits (142), Expect = 9e-09, Method: Compositional matrix adjust.
Identities = 49/204 (24%), Positives = 90/204 (44%), Gaps = 16/204 (7%)
Frame = -3
Query: 449 IGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKF----LQEALTMRQFDHPHI 504
IG+G FG+V + + VA+K D+ +E F L+E ++ +H ++
Sbjct: 1718 IGQGTFGEVFKA---RCKKTKQVVAMK---KVLMDNEKEGFPITALREIKILQLLNHENV 1557
Query: 505 VKLIGVIT---------ENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTAL 555
V LI + + ++ +++ E C +L L +L + QL L
Sbjct: 1556 VDLIEICSTKATSANRYKSMFYLVFEFCE-HDLAGLLSNMSVVFNLPEIKEVMKQLMNGL 1380
Query: 556 AYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSR-YMEDSTYYKASKGKLPIKWMAPES 614
Y+ + +HRD+ A N+L++ +KL DFGL+R + + ++ W P
Sbjct: 1379 YYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRPPE 1200
Query: 615 INF--RRFTSASDVWMFGVCMWEI 636
+ R +++A D W G M E+
Sbjct: 1199 LLLGDRNYSTAIDQWGAGCIMAEM 1128
>19761
Length = 473
Score = 58.9 bits (141), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 34/130 (26%), Positives = 67/130 (51%), Gaps = 8/130 (6%)
Frame = -3
Query: 544 LILYAYQLSTALAYLESKR--FVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKAS 601
++ + Q ++AL Y+ + +HRD+ +N+ V+ V+LGD GL+R + + S
Sbjct: 417 IVCWLMQTASALNYMHTHTPVILHRDLKPQNIYVTEKGDVRLGDLGLARKLTGPADFATS 238
Query: 602 KGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIG------R 655
+ I +++PE ++ + + S SD+W G ++I G K +D +G +
Sbjct: 237 QVG-TIMYLSPEILSQQPYNSKSDIWSLGCVFYDI--------TGKKGSDEMGVMFLLVQ 85
Query: 656 IENGERLPMP 665
+ G +LP+P
Sbjct: 84 VMGGRKLPLP 55
>04591
Length = 1117
Score = 58.5 bits (140), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 46/167 (27%), Positives = 75/167 (44%), Gaps = 16/167 (9%)
Frame = -2
Query: 490 LQEALTMRQFDHPHIVKLIGVI---------TENPVWIIMELCTLGELRSFLQVRKYSLD 540
L+E ++Q +H ++V+L + ++ ++I E C +L L +
Sbjct: 1077 LREIKILQQLEHENVVQLQEICHTQAGPYNRYKSTFYLIFEYCDY-DLAGLLNNLRVKFS 901
Query: 541 LASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKA 600
LA QL L Y+ +K+ +HRDI A N+L++ + +KL DFGLSR S K
Sbjct: 900 LADKKNLMSQLLNGLFYIHTKQILHRDIKAANILLTRDGVLKLADFGLSRPWVKS---KR 730
Query: 601 SKGKLPIKWMAPESINF--RRFTSASDVWMFGVCMWEI-----LMHG 640
++ W P + R + D+W G M E+ LM G
Sbjct: 729 LTNRVVTLWYRPPELLLGEREYGPEIDMWGVGCIMAEMWSRKPLMQG 589
>03240
Length = 1683
Score = 56.6 bits (135), Expect = 5e-08, Method: Compositional matrix adjust.
Identities = 63/263 (23%), Positives = 108/263 (41%), Gaps = 56/263 (21%)
Frame = -3
Query: 438 IQRERIELGRC-------IGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFL 490
I+ +R ++ +C +G G FG+V + + A+KT + SD ++ +
Sbjct: 1321 IRLKRAKMDKCMFEKIKTLGVGAFGEVS---LCRKNDTGMLYAMKTLRK--SDVLKRNQV 1157
Query: 491 QEALTMRQF----DHPHIVKLIGVITE-NPVWIIMELCTLGELRSFLQVRKYSLDLASLI 545
R D+ +VKL + N ++ +M+ G+L L +R LD
Sbjct: 1156 AHVKAERDILAEADNEWVVKLYYSFQDHNYLYFVMDYVPGGDLMGLL-IRMEILDEPLAR 980
Query: 546 LYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLS---RYMEDSTYYK--- 599
Y +L A+ + F+HRDI N+L+ N +KL DFGL R+ +S YY+
Sbjct: 979 FYVAELVQAIESVHRMGFIHRDIKPDNILIDRNGHIKLTDFGLCTGFRWTHNSKYYQRDG 800
Query: 600 --ASKGKLPIK-----------------------------------WMAPESIN-FRRFT 621
A + + +K ++APE ++ +T
Sbjct: 799 THARQDSMEVKCQLDEQCQCEILKPLERRRKREQRCLAHSLVGTPNYIAPEVLSRLGGYT 620
Query: 622 SASDVWMFGVCMWEILMHGVKPF 644
S D W GV ++E+L+ G PF
Sbjct: 619 SVCDWWSVGVILFEMLV-GHPPF 554
>21079
Length = 878
Score = 56.6 bits (135), Expect = 5e-08, Method: Compositional matrix adjust.
Identities = 34/128 (26%), Positives = 66/128 (51%), Gaps = 2/128 (1%)
Frame = +1
Query: 518 IIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSS 577
++ME GEL + + L + + Q+ + + Y+ ++ +H D+ NVL S
Sbjct: 55 LVMEFVGAGELFERVIRDDFVLTERDCVHFVRQICSGVGYMHTQSILHLDLKPENVLCVS 234
Query: 578 NDC--VKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWE 635
++ +K+ DFGL+R+ + + G P +++APE +N+ +D+W GV +
Sbjct: 235 DNSNQIKIIDFGLARFYKPGDSLQVLFGT-P-EFIAPEVVNYDEINFTTDMWSIGVICY- 405
Query: 636 ILMHGVKP 643
IL+ G+ P
Sbjct: 406 ILLSGLSP 429
>01707
Length = 757
Score = 55.8 bits (133), Expect = 8e-08, Method: Compositional matrix adjust.
Identities = 53/199 (26%), Positives = 90/199 (45%), Gaps = 10/199 (5%)
Frame = +1
Query: 449 IGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKF-LQEALTMRQFDHPHIVKL 507
IGEG +G V + + + VAIK D + +K ++E ++Q HP++V+L
Sbjct: 88 IGEGSYGVVFK---CRNKETSQLVAIKKFVESEDDPLIKKIAMREIRMLKQLKHPNLVRL 258
Query: 508 IGVITENP----VWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRF 563
I V V+ ++ L EL + R + I+Y Q A+ +
Sbjct: 259 IEVFRRKKRLHLVFDYVDHTLLNELDRY--PRGLPEPMVKRIIY--QTLLAVNFCHQYNT 426
Query: 564 VHRDIAARNVLVSSNDCVKLGDFGLSRYM----EDSTYYKASKGKLPIKWMAPE-SINFR 618
+HRD+ N+L++ VKL DFG +R + ++ T Y A++ + APE +
Sbjct: 427 IHRDVKPENILITRQGQVKLCDFGFARILTGPGDEYTDYVATRW-----YRAPELLVGDT 591
Query: 619 RFTSASDVWMFGVCMWEIL 637
++ DVW G E+L
Sbjct: 592 QYGPPVDVWAIGCVFAELL 648
>18484
Length = 635
Score = 55.5 bits (132), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 28/113 (24%), Positives = 59/113 (52%)
Frame = +1
Query: 546 LYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKL 605
YA +++ L +L + ++RD+ NV++ S +K+ DFG+ + +
Sbjct: 55 FYAAEIAVGLFFLHDQGIIYRDLKLDNVMLDSEGHIKIADFGMCKEGMTGDATTRTFCGT 234
Query: 606 PIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIEN 658
P ++APE + ++ ++ + D W +GV ++E+L G PF G +++ I +
Sbjct: 235 P-DYIAPEIVLYQPYSKSVDWWAYGVLLFEMLA-GQPPFDGEDEDELFSSITD 387
>07836
Length = 1478
Score = 54.3 bits (129), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 65/260 (25%), Positives = 112/260 (43%), Gaps = 43/260 (16%)
Frame = -1
Query: 486 REKFLQEALTMRQFDHPHIVKLI-----GVITENPVWIIMELCTLGELRSFLQVRKYSLD 540
RE L + + +R H +I+ I G + +++I + G L +L R LD
Sbjct: 1424 RETELYQTVLLR---HENILGFIAADIKGTGSWTQLFLITDYHENGSLHDYLLSR--VLD 1260
Query: 541 LASLILYAYQLSTALAYLESKRF--------VHRDIAARNVLVSSNDCVKLGDFGLS-RY 591
+ ++ A+ LA+L + F HRDI ++N+LV N + D GL+ RY
Sbjct: 1259 SSEMLALAHSAICGLAHLHIEIFGTRGKPAIAHRDIKSKNILVKKNGTCCIADLGLAVRY 1080
Query: 592 MEDSTYYKASKG--KLPIKWMAPESI-------NFRRFTSASDVWMFGVCMWEI----LM 638
+ +S + + ++MAPE + NF F A D++ FG+ MWEI ++
Sbjct: 1079 ISESNEVDVAPNPRQGTKRYMAPEVLEMLLNVKNFDAFKQA-DMYAFGLVMWEIARCCVI 903
Query: 639 HGVK-----PFQGVKNND--------VIGRIENGERLPMPPNCPP---TLYSLMTKCWAY 682
GV PF +D V+ + +P+ P + +M +CW+
Sbjct: 902 GGVAEEYQVPFYNCLPHDPSFEDVRLVVSVDKVRPDIPLRWQEDPIMKVMVKVMCECWSG 723
Query: 683 DPSRRPRFTELKAQLSTILE 702
+P+ R +K L + E
Sbjct: 722 NPAARLTALRVKKTLGKLSE 663
>01966
Length = 1735
Score = 53.9 bits (128), Expect = 4e-07, Method: Compositional matrix adjust.
Identities = 30/113 (26%), Positives = 62/113 (54%), Gaps = 3/113 (2%)
Frame = -1
Query: 481 TSDSVREKFLQEALTMRQFDHPHIVKLIGVITENP-VWIIMELCTLGELRSFLQV--RKY 537
+ D V ++E +R+ H +IV L VI E+ ++++ E ++ +L+ ++
Sbjct: 1597 SEDGVPSSAIREIAMLRELRHTNIVCLEDVIMEDERLFLVFEFLSM-DLKMYIDKFPEGV 1421
Query: 538 SLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSR 590
LD + Y +Q+ T + + +R VHRD+ +N+L++ +K+ DFG++R
Sbjct: 1420 VLDRRLVKSYVFQIVTGINFCHQRRIVHRDLKPQNLLINHTGAIKIADFGMAR 1262
>26711
Length = 405
Score = 50.8 bits (120), Expect = 3e-06, Method: Composition-based stats.
Identities = 32/102 (31%), Positives = 58/102 (56%), Gaps = 5/102 (4%)
Frame = -2
Query: 550 QLSTALAYLESKRFVHRDIAARNVLVSSN--DCVKLGDFGLSRYM---EDSTYYKASKGK 604
Q+ L ++ ++ VH D+ N+L+S + D V+L DFGL+R + +++ + G
Sbjct: 392 QVLDILQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARKLYPPQETFLNHGTPG- 216
Query: 605 LPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQG 646
+ +PE+++ + ++ASDVW GV + IL+ G PFQ
Sbjct: 215 ----FTSPEALDVKPISTASDVWGVGVLAY-ILLSGQSPFQA 105
>15910
Length = 1361
Score = 50.8 bits (120), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 34/107 (31%), Positives = 55/107 (51%), Gaps = 3/107 (2%)
Frame = +2
Query: 557 YLESKRFVHRDIAARNVL---VSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPE 613
Y+ + VHRD+ N+L ++ + +KL DFGLSR +E G P + APE
Sbjct: 509 YIHANGVVHRDLKPENLLYECMTDDSKLKLADFGLSRIIEPEVQMSTVCGT-P-GYCAPE 682
Query: 614 SINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGE 660
+ ++T + D+W GV + IL+ G +PF ++ +I GE
Sbjct: 683 VLKGDKYTPSVDMWSVGVIAY-ILLCGYEPFFAENEFEMYRKIIKGE 820
>12672
Length = 773
Score = 49.3 bits (116), Expect = 9e-06, Method: Compositional matrix adjust.
Identities = 38/162 (23%), Positives = 66/162 (40%), Gaps = 16/162 (9%)
Frame = +3
Query: 552 STALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGL---SRYMEDSTYYKASKGKLPIK 608
++ + YL VHRDI N+L+ S K+GDF + E T AS
Sbjct: 21 ASGIQYLNDNGHVHRDIKTANILLDSEYTAKVGDFATVVSAPSGEGKTVQNASVVIGTAA 200
Query: 609 WMAPESINFRRFTSASDVWMFGVCMWEILMHGVKP-------------FQGVKNNDVIGR 655
++APE+I+F ++ D + FGV + E++ V + V+ + I
Sbjct: 201 YLAPEAIHF-DVSTKLDSYSFGVVLLEVITGLVAQDYSREERTLSSHIMENVEEPEEIHD 377
Query: 656 IENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQL 697
+ P LY + +C +RP +++ +L
Sbjct: 378 FVDQSAGTWPDGAVDKLYDISMRCLNLSKKQRPNVKDIRPEL 503
>25550
Length = 941
Score = 48.9 bits (115), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 25/76 (32%), Positives = 37/76 (48%), Gaps = 1/76 (1%)
Frame = +3
Query: 629 FGVC-MWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRR 687
G C +W++ + GV +V +E G R+ P P +Y LM KCW +DP R
Sbjct: 12 MGACDIWDVX------YPGVDLTEVYHLLERGYRMERPQGTPADVYILMLKCWQWDPKER 173
Query: 688 PRFTELKAQLSTILEE 703
P F E+ L + E+
Sbjct: 174 PTFKEIHYLLENMFEK 221
>32264
Length = 287
Score = 48.5 bits (114), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 21/48 (43%), Positives = 28/48 (58%)
Frame = +1
Query: 656 IENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEE 703
IE+G RL P P ++Y LM +CW Y P +RP F EL L I+ +
Sbjct: 1 IEDGYRLQQNPQTPDSVYKLMLRCWEYVPEKRPHFKELYTSLKDIVRK 144
>21433
Length = 590
Score = 48.1 bits (113), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 30/98 (30%), Positives = 49/98 (50%)
Frame = +2
Query: 547 YAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLP 606
Y YQLS+AL Y ++ +HRDI N+L+ +K+ DFG S + S + +
Sbjct: 182 YIYQLSSALEYCHYRKVIHRDIKPENLLLGLKGDLKIADFGWSVHAPSS---RRTTMCGT 352
Query: 607 IKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPF 644
+ ++ PE + + D+W GV +E L+ G P
Sbjct: 353 LDYLPPEMVEGKTHDENVDLWSLGVLCYEFLV-GTPPL 463
>28157
Length = 400
Score = 46.2 bits (108), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 31/112 (27%), Positives = 54/112 (48%), Gaps = 6/112 (5%)
Frame = +3
Query: 482 SDSVREKFLQEALTMRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVR--KYSL 539
S+ ++ F+QE + + HP+IV L G ++PV ++ME G L + L +
Sbjct: 30 SEQEKKSFMQELKQLSRVSHPNIVCLYGACRDHPVCLVMEYAEGGSLYNVLHGSGPQPQY 209
Query: 540 DLASLILYAYQLSTALAYLES---KRFVHRDIAARN-VLVSSNDCVKLGDFG 587
A + + Q + + YL K +HRD+ N +L+ +K+ DFG
Sbjct: 210 TAAHAMNWLLQCALGVEYLHGMKPKALIHRDLKPPNLLLIQCGTKLKICDFG 365
>26560
Length = 398
Score = 43.9 bits (102), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 32/113 (28%), Positives = 58/113 (51%), Gaps = 1/113 (0%)
Frame = -1
Query: 546 LYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKL 605
YA ++ L ++ S+ V+RD+ N+L+ N V++ D GL+ D + +
Sbjct: 344 FYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGLA---CDFSKKRPHASVG 174
Query: 606 PIKWMAPESI-NFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIE 657
+MAPE + + + S++D + FG CM L+ G PF+ ++N RI+
Sbjct: 173 THGYMAPEVLMKGQSYDSSADWFSFG-CMLYKLLKGHSPFR--QHNQGQARID 24
>04138
Length = 800
Score = 43.5 bits (101), Expect = 5e-04, Method: Compositional matrix adjust.
Identities = 24/85 (28%), Positives = 42/85 (49%), Gaps = 3/85 (3%)
Frame = +1
Query: 555 LAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSR-YMEDSTYYKASKGKLPIKWMAPE 613
L Y+ + +HRD+ A N+L++ +KL DFGL+R + + ++ W P
Sbjct: 52 LYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRPP 231
Query: 614 SINF--RRFTSASDVWMFGVCMWEI 636
+ R +++A D W G M E+
Sbjct: 232 ELLLGDRNYSTAIDQWGAGCIMAEM 306
>01392
Length = 1806
Score = 42.4 bits (98), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 37/123 (30%), Positives = 59/123 (47%), Gaps = 12/123 (9%)
Frame = -1
Query: 542 ASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSND---CVKLGDFGLSRYME-DSTY 597
ASL++ ++ AL +L SK HRD+ N+L D VK+ DF L+ + D
Sbjct: 1785 ASLVVR--HIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGISCDGDG 1612
Query: 598 YKASKGKLPI---KWMAPESINFRRFTSAS-----DVWMFGVCMWEILMHGVKPFQGVKN 649
K + P+ ++MAPE ++ S S D+W G+ ++ I++ G PF G
Sbjct: 1611 TKTPELLTPVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILY-IMLCGYPPFYGQCG 1435
Query: 650 NDV 652
D
Sbjct: 1434 EDC 1426
>12786
Length = 460
Score = 41.2 bits (95), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 39/143 (27%), Positives = 69/143 (48%), Gaps = 23/143 (16%)
Frame = -3
Query: 538 SLDLASLILYAYQLSTALAYLESKRFVHRDIAARN-VLVSSNDCVKLGDFGLSRYMED-- 594
LD + Y ++ A+ L ++ +H D+ N +LV+ N +KL DFG++ ++
Sbjct: 422 GLDRMMIKFYWREMLRAVKALHNEGVIHSDLKPANFMLVAGN--LKLIDFGIANTLQQDK 249
Query: 595 STYYKASKGKLPIKWMAPESINFRRFTSA--------------------SDVWMFGVCMW 634
++ K S+ P +M+PE+I SA SDVW G C+
Sbjct: 248 TSVLKDSRVGTP-SYMSPEAIMAACDDSADDSMEEDGHRTKPKYKVGVRSDVWSLG-CIL 75
Query: 635 EILMHGVKPFQGVKNNDVIGRIE 657
+++G PFQ +KNN +G+++
Sbjct: 74 YNMVYGRTPFQHIKNN--MGKLQ 12
>07933
Length = 728
Score = 40.0 bits (92), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 15/39 (38%), Positives = 26/39 (66%)
Frame = +3
Query: 665 PPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEE 703
P CP LY++M +CW+ +PS RP F +L+ + ++E+
Sbjct: 3 PNYCPNLLYNIMMQCWSAEPSARPTFHKLEQDIVAMVEQ 119
>03508
Length = 1463
Score = 40.0 bits (92), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 26/100 (26%), Positives = 48/100 (48%), Gaps = 2/100 (2%)
Frame = +1
Query: 546 LYAYQLSTALAYLESKRFVHRDIAARNVLVS-SNDCVKLGDFGLSRYMEDSTYYKASKGK 604
Y Y+L AL + S +HRD+ NV++ N ++L D+GL+ + Y
Sbjct: 883 FYLYELMKALDFCHSMGIMHRDVKPHNVMIDHENKKLRLIDWGLAEFYHPGMEYNVRVAS 1062
Query: 605 LPIKWMAPE-SINFRRFTSASDVWMFGVCMWEILMHGVKP 643
K PE ++++ + + D+W G CM+ ++ +P
Sbjct: 1063RYFK--GPELLLDYQMYDYSLDMWSLG-CMFASMIFRKEP 1173
>37602
Length = 804
Score = 38.5 bits (88), Expect = 0.014, Method: Compositional matrix adjust.
Identities = 22/71 (30%), Positives = 32/71 (45%)
Frame = -1
Query: 516 VWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLV 575
+WI ME C G ++ V L + + L YL + +HRDI N+L+
Sbjct: 294 LWIAMEYCGGGSMQDIYHVTG-PLTEPQIAFVCRETLKGLHYLHRRGKMHRDIKGANILL 118
Query: 576 SSNDCVKLGDF 586
+ VKL DF
Sbjct: 117 TEEGDVKLADF 85
>38046
Length = 446
Score = 38.1 bits (87), Expect = 0.018, Method: Composition-based stats.
Identities = 14/32 (43%), Positives = 24/32 (75%)
Frame = -1
Query: 551 LSTALAYLESKRFVHRDIAARNVLVSSNDCVK 582
++ A+AY+E + F+HR++ RN+LV N+ VK
Sbjct: 98 IADAMAYMEKENFIHRNLGDRNILVGPNNRVK 3
>18481
Length = 437
Score = 37.4 bits (85), Expect = 0.031, Method: Composition-based stats.
Identities = 26/82 (31%), Positives = 44/82 (53%), Gaps = 4/82 (4%)
Frame = -1
Query: 518 IIMELCTLG-ELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVS 576
++MEL LG L + K L ++++ + QL + L ++ K F+HRD+ N L+
Sbjct: 266 LVMEL--LGPSLEELFVICKRRFTLKTILMVSDQLLSRLEFIHQKCFIHRDLKPDNFLMG 93
Query: 577 -SNDCVKLG--DFGLSRYMEDS 595
C +L DFGLS+ +D+
Sbjct: 92 LGRHCHRLYIIDFGLSKRYKDT 27
>11185
Length = 473
Score = 37.4 bits (85), Expect = 0.034, Method: Compositional matrix adjust.
Identities = 37/168 (22%), Positives = 62/168 (36%), Gaps = 21/168 (12%)
Frame = +1
Query: 547 YAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRY----MEDSTYYKASK 602
+ L T L Y+ S + D+ VL+ ++ +K DFGLS+ +E+ + A
Sbjct: 16 FGIHLVTGLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEA 195
Query: 603 G-------------KLPIK----WMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQ 645
G ++P +MAPE + SD+W G +E+
Sbjct: 196 GDQWNIQSAEEMMKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMF-------- 351
Query: 646 GVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTEL 693
+G RL P+ P +L+ D +RR + L
Sbjct: 352 ------------SGSRLSAKPS--PEFLNLLESLLQKDSTRRLSWASL 453
>02638
Length = 1490
Score = 36.2 bits (82), Expect = 0.064, Method: Composition-based stats.
Identities = 28/92 (30%), Positives = 42/92 (45%), Gaps = 5/92 (5%)
Frame = +1
Query: 607 IKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKP---FQGVKNN-DVIGRIENG-ER 661
I +MAPE + + A DVW G M E M +P + N+ +I +I + +
Sbjct: 28 IAFMAPEVLRGESYGRACDVWSVGCVMIE--MCTCRPPWNSHDISNHLALIFKIASSVDP 201
Query: 662 LPMPPNCPPTLYSLMTKCWAYDPSRRPRFTEL 693
P+P N P + LM +C D RP +L
Sbjct: 202 PPIPENMSPPVRDLMLRCLEQDSDFRPSAKDL 297
>00486
Length = 797
Score = 35.0 bits (79), Expect = 0.17, Method: Compositional matrix adjust.
Identities = 24/81 (29%), Positives = 36/81 (44%)
Frame = -2
Query: 607 IKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPP 666
I++MAPE + A D W G M+++L G PF I +I G +L +PP
Sbjct: 766 IEYMAPEILTRTGHGKAVDWWSLGALMYDMLT-GSPPFTAENRKKTIDKILKG-KLNLPP 593
Query: 667 NCPPTLYSLMTKCWAYDPSRR 687
L+ K +P+ R
Sbjct: 592 YLTNEARGLIKKLLRKNPAER 530
>26009
Length = 886
Score = 34.7 bits (78), Expect = 0.22, Method: Compositional matrix adjust.
Identities = 15/30 (50%), Positives = 21/30 (70%)
Frame = +3
Query: 550 QLSTALAYLESKRFVHRDIAARNVLVSSND 579
QL +AL ++ SK+ VHRDI NVL+ + D
Sbjct: 735 QLVSALDFMHSKQLVHRDIKPENVLILTPD 824
>16708
Length = 1397
Score = 34.3 bits (77), Expect = 0.30, Method: Compositional matrix adjust.
Identities = 17/49 (34%), Positives = 27/49 (55%)
Frame = -1
Query: 542 ASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSR 590
A + A Q AL ++ VH D+ A NVLV ++ KL D+G+++
Sbjct: 1094 AMVCCIAGQXVCALEHIHELGVVHMDVKADNVLVDAHGNCKLTDYGIAQ 948
>15741
Length = 402
Score = 33.9 bits (76), Expect = 0.36, Method: Composition-based stats.
Identities = 15/44 (34%), Positives = 24/44 (54%)
Frame = -3
Query: 531 FLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVL 574
FL L +A ++ +A++ + + VHRD+AARNVL
Sbjct: 133 FLTSTANDLTARDFFSFALHVARGMAHVANNKIVHRDVAARNVL 2
>27287
Length = 514
Score = 33.9 bits (76), Expect = 0.36, Method: Compositional matrix adjust.
Identities = 13/37 (35%), Positives = 20/37 (54%)
Frame = -2
Query: 665 PPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTIL 701
PP ++ +M CW DP+ RP F+ L +L +L
Sbjct: 504 PPYASSEMFGIMHSCWQEDPNDRPSFSRLVQELDKML 394
>27405
Length = 532
Score = 33.9 bits (76), Expect = 0.40, Method: Compositional matrix adjust.
Identities = 14/44 (31%), Positives = 26/44 (59%)
Frame = -3
Query: 546 LYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLS 589
YA ++ L ++ S+ V+RD+ N+L+ N V++ D GL+
Sbjct: 242 FYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGLA 111
>21210
Length = 518
Score = 33.1 bits (74), Expect = 0.62, Method: Compositional matrix adjust.
Identities = 30/104 (28%), Positives = 47/104 (45%), Gaps = 7/104 (6%)
Frame = +3
Query: 609 WMAPESINFRR----FTSASDVWMFGVCMWEILMHGVKPFQG-VKNNDVIGRIENGER-- 661
+MAPE I+ R + SDVW G+ + E L G P++ V D + ++ G
Sbjct: 18 YMAPERIDPRASSHGYDVRSDVWSLGITLME-LATGRFPYRKWVSIFDQLQQVVRGVAPC 194
Query: 662 LPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEK 705
LP + + KC D +RP++ +L A L EE+
Sbjct: 195 LPHDGAFSHDFVNFVNKCLTKDEKQRPKYNKLLAHPFVRLYEEQ 326
>25019
Length = 730
Score = 31.6 bits (70), Expect = 1.9, Method: Composition-based stats.
Identities = 22/62 (35%), Positives = 29/62 (46%)
Frame = +3
Query: 569 AARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWM 628
AA NVL+ + VKL DFGL + T + I++MAPE + A D W
Sbjct: 255 AAENVLLDKDGHVKLTDFGLCKEAITGTRVTHTFCG-TIEYMAPEILTRTGHGKAVDWWS 431
Query: 629 FG 630
G
Sbjct: 432 LG 437
>32359
Length = 928
Score = 30.8 bits (68), Expect = 3.5, Method: Compositional matrix adjust.
Identities = 35/128 (27%), Positives = 60/128 (46%), Gaps = 9/128 (7%)
Frame = -1
Query: 446 GRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIV 505
+ IG G FG V+Q + + + VAIK K + + LQ MR+ +H +IV
Sbjct: 415 AKVIGNGSFGVVYQAKLV---DTSELVAIK--KVLQDKRFKNRELQ---IMRKLEHQNIV 260
Query: 506 KLIGVI-----TENPVWI--IMELC--TLGELRSFLQVRKYSLDLASLILYAYQLSTALA 556
KL ++ V++ ++E T+ + K ++ + + LY YQL +LA
Sbjct: 259 KLKFFFYSSGEKKDEVFLNLVLEYVPETVYRVARHYSKSKQTIPILYIKLYMYQLFRSLA 80
Query: 557 YLESKRFV 564
Y+ S+ V
Sbjct: 79 YIHSQACV 56
>22855
Length = 540
Score = 30.0 bits (66), Expect = 5.7, Method: Composition-based stats.
Identities = 21/60 (35%), Positives = 31/60 (51%), Gaps = 1/60 (1%)
Frame = -2
Query: 18 SSKIMAAAYLDPNL-NHTPNSSTKTHLGTGMERSPGAMERVLKVFHYFESNSEPTTWASI 76
SSK++ P+L + + ST +H GM PG+ V HY +N +P TWAS+
Sbjct: 329 SSKMVHGGLGSPSLADSMGHHSTSSH---GMAYFPGSA--VTPGSHYLTANRQPLTWASM 165
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000264255 | hsapiens_gene_ensembl | Thioredoxin
domain-containing protein 9 (Protein 1-4) (ATP-binding protein
associated with cell differentiation).
[Source:Uniprot/SWISSPROT;Acc:O14530]
(226 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
39480 217 2e-57
04576 105 2e-23
06852 27 4.8
>39480
Length = 1229
Score = 217 bits (553), Expect = 2e-57, Method: Compositional matrix adjust.
Identities = 99/205 (48%), Positives = 140/205 (68%), Gaps = 2/205 (0%)
Frame = +1
Query: 13 VLEHQLLQTTKLVEEHLDSEIQKLDQMXXXXXXXXXXXXXXXXXXXXXXXXEWLSKGHGE 72
++E LLQ T+++E+ +D EI KL+ M EW++ GHG+
Sbjct: 130 LVEQTLLQATQMIEQQVDQEIAKLENMEEDDFEAVRRRRMIALKKQQQQKQEWMNNGHGD 309
Query: 73 YREIPSERDFFQEVKESENVVCHFYRDSTFRCKILDRHLAILSKKHLETKFLKLNVEKAP 132
Y EI SE++FF++ K+S+N+VCHFYRD+TFRCKI+D+HL +L+ KH+E KF+++NVEK P
Sbjct: 310 YTEISSEKEFFEQSKKSKNLVCHFYRDTTFRCKIVDKHLGLLAPKHMEAKFIRINVEKCP 489
Query: 133 FLCERLHIKVIPTLALLKDGKTQDYVVGFTDLGNTDDFTTETLEWRLGSSDILNYSGNLM 192
FL ERL IKV+PT+ + K+GKT DY+VGF DLG D+F TE +EWRLG +D+++YSG+LM
Sbjct: 490 FLVERLRIKVLPTICIAKEGKTTDYIVGFDDLGGKDEFPTEMMEWRLGRTDVISYSGDLM 669
Query: 193 EPPF--QNQKKFGTNFTKLEKKTIR 215
PP+ + K K KTIR
Sbjct: 670 TPPWDPNSGGKSILGHAKRSNKTIR 744
>04576
Length = 1310
Score = 105 bits (261), Expect = 2e-23, Method: Compositional matrix adjust.
Identities = 49/122 (40%), Positives = 72/122 (59%)
Frame = +2
Query: 67 SKGHGEYREIPSERDFFQEVKESENVVCHFYRDSTFRCKILDRHLAILSKKHLETKFLKL 126
K HGEY + +E+ F +E V HF+ RC ++D HL LS+++ ETKF ++
Sbjct: 173 GKQHGEYSLLETEKGFLDMTTGTERCVVHFFHPDFRRCAVVDTHLQTLSQRYFETKFARI 352
Query: 127 NVEKAPFLCERLHIKVIPTLALLKDGKTQDYVVGFTDLGNTDDFTTETLEWRLGSSDILN 186
+VE A FL +L ++++P + K G D +VGF +LGNTDDF TE LE RL S +
Sbjct: 353 SVESAKFLVSKLKVQILPAIFCFKKGIVVDKIVGFEELGNTDDFRTEILEHRLARSGCIQ 532
Query: 187 YS 188
+
Sbjct: 533 MA 538
>06852
Length = 1632
Score = 27.3 bits (59), Expect = 4.8, Method: Compositional matrix adjust.
Identities = 22/72 (30%), Positives = 34/72 (47%), Gaps = 2/72 (2%)
Frame = +3
Query: 86 VKESEN--VVCHFYRDSTFRCKILDRHLAILSKKHLETKFLKLNVEKAPFLCERLHIKVI 143
V E EN ++ HF ++S F+C H I+ ++++ L LN K P L I
Sbjct: 1359 VSERENPIILTHFVKESGFQC--CXXHXKIVLNSXVKSQNLXLNSAKLPSL--------I 1508
Query: 144 PTLALLKDGKTQ 155
P+LA + Q
Sbjct: 1509 PSLAXMAIFVAQ 1544
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000309591 | hsapiens_gene_ensembl | cAMP-dependent
protein kinase, alpha-catalytic subunit (EC 2.7.11.11) (PKA C-alpha).
[Source:Uniprot/SWISSPROT;Acc:P17612]
(351 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
03240 219 2e-57
30755 170 8e-43
18484 142 2e-34
27405 124 7e-29
00486 120 8e-28
31885 115 3e-26
15910 114 6e-26
18921 110 7e-25
12721 110 1e-24
09606 102 3e-22
26560 101 4e-22
01707 100 1e-21
00300 99 3e-21
14420 99 3e-21
18663 97 8e-21
13592 93 2e-19
26156 82 2e-19
01392 92 3e-19
17975 86 3e-17
13066 84 9e-17
06405 84 1e-16
01060 81 6e-16
21079 80 8e-16
21433 78 5e-15
17722 75 3e-14
01756 74 9e-14
00392 72 2e-13
27546 71 6e-13
09007 71 7e-13
19094 69 2e-12
25019 69 2e-12
01718 69 3e-12
19761 68 4e-12
26711 68 6e-12
11185 66 3e-11
38560 65 4e-11
13212 64 8e-11
29581 64 8e-11
28638 64 9e-11
28157 63 2e-10
14126 62 3e-10
19301 61 7e-10
01966 61 8e-10
21808 59 3e-09
04852 59 4e-09
04591 57 1e-08
32957 56 2e-08
12786 55 5e-08
07940 55 5e-08
04138 54 1e-07
11780 54 1e-07
16708 52 3e-07
03508 52 4e-07
20152 51 8e-07
37602 50 1e-06
00715 50 1e-06
14116 48 7e-06
27274 47 1e-05
07291 46 2e-05
17300 46 2e-05
02638 45 6e-05
17932 44 8e-05
33586 44 1e-04
18401 43 2e-04
12672 41 7e-04
31489 41 0.001
29590 40 0.001
26009 40 0.001
11404 40 0.001
14477 40 0.001
37063 39 0.005
17516 38 0.005
20640 38 0.006
18481 37 0.008
18996 37 0.010
17637 37 0.011
17253 37 0.012
21800 37 0.014
01106 37 0.017
06358 36 0.021
26052 36 0.024
36481 36 0.029
25360 35 0.040
11089 35 0.054
21210 34 0.068
28865 33 0.14
17591 33 0.20
30339 32 0.34
31120 32 0.52
00638 31 0.84
16350 30 1.3
32357 30 1.4
06167 29 3.1
36002 29 3.6
23319 28 4.3
29360 28 7.9
>03240
Length = 1683
Score = 219 bits (557), Expect = 2e-57, Method: Compositional matrix adjust.
Identities = 128/356 (35%), Positives = 192/356 (53%), Gaps = 56/356 (15%)
Frame = -3
Query: 44 FERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPF 103
FE+IKTLG G+FG V L + +TG YAMK L K V+K Q+ H E+ IL + +
Sbjct: 1285 FEKIKTLGVGAFGEVSLCRKNDTGMLYAMKTLRKSDVLKRNQVAHVKAERDILAEADNEW 1106
Query: 104 LVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDL 163
+VKL +SF+D++ LY VM+YVPGG++ L R+ EP ARFY A++V E +H +
Sbjct: 1105 VVKLYYSFQDHNYLYFVMDYVPGGDLMGLLIRMEILDEPLARFYVAELVQAIESVHRMGF 926
Query: 164 IYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWT------------------------- 198
I+RD+KP+N+LID+ G+I++TDFG G WT
Sbjct: 925 IHRDIKPDNILIDRNGHIKLTDFGLC---TGFRWTHNSKYYQRDGTHARQDSMEVKCQLD 755
Query: 199 -------------------------LCGTPEYLAPEIILSK--GYNKAVDWWALGVLIYE 231
L GTP Y+APE +LS+ GY DWW++GV+++E
Sbjct: 754 EQCQCEILKPLERRRKREQRCLAHSLVGTPNYIAPE-VLSRLGGYTSVCDWWSVGVILFE 578
Query: 232 MAAGYPPFFADQPIQIYEKIVSGK--VRFP--SHFSSDLKDLLRNLLQVDLTKRFGNLKN 287
M G+PPF+A+ P + K+++ K ++ P S+ S KDL+ L R G N
Sbjct: 577 MLVGHPPFYANTPAETQYKVINWKDMLKIPRESNLSQPAKDLILRLC-CGSDDRLG--LN 407
Query: 288 GVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEK 343
G +IK H +FA ++ + RK + P++P + DTSNFD + +++R S +E+
Sbjct: 406 GAGEIKTHMFFAGVNFETL--RKQQPPYVPNIRYATDTSNFDPVDPDKLRNSDSEE 245
>30755
Length = 1137
Score = 170 bits (430), Expect = 8e-43, Method: Compositional matrix adjust.
Identities = 88/218 (40%), Positives = 126/218 (57%), Gaps = 4/218 (1%)
Frame = +2
Query: 132 HLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKR 191
HL F+E RFY A+I+ YLHS +IYRDLK ENLL+D+ G+I+V DFG K
Sbjct: 2 HLSHERIFTEERTRFYGAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCKE 181
Query: 192 --VKGRTW-TLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIY 248
GRT T CGTPEYLAPE++ Y +AVDWW GV++YEM G PF+ ++
Sbjct: 182 DITYGRTTKTFCGTPEYLAPEVLDDNDYGRAVDWWGTGVVMYEMICGRLPFYNRDHDVLF 361
Query: 249 EKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQ 308
I+ V+FP + + + K LL LL D R G ++ V +I+ H +FA+ +W + Q
Sbjct: 362 TLILVEDVKFPRNITDEAKSLLSGLLAKDPRNRLGGGQDDVKEIQAHPFFASINWTDLVQ 541
Query: 309 RKVEAPFIPKFKGPGDTSNFD-DYEEEEIRVSINEKCG 345
+K+ PF P+ DT FD ++ E + ++ + G
Sbjct: 542 KKITPPFKPQVTSDTDTRYFDEEFTGESVELTPPDPTG 655
>18484
Length = 635
Score = 142 bits (358), Expect = 2e-34, Method: Compositional matrix adjust.
Identities = 66/159 (41%), Positives = 100/159 (62%), Gaps = 3/159 (1%)
Frame = +1
Query: 128 EMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFG 187
++ +++ G+F EP A FYAA+I + +LH +IYRDLK +N+++D +G+I++ DFG
Sbjct: 1 DLMYRIQQEGKFKEPVAAFYAAEIAVGLFFLHDQGIIYRDLKLDNVMLDSEGHIKIADFG 180
Query: 188 FAKRV---KGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQP 244
K T T CGTP+Y+APEI+L + Y+K+VDWWA GVL++EM AG PPF +
Sbjct: 181 MCKEGMTGDATTRTFCGTPDYIAPEIVLYQPYSKSVDWWAYGVLLFEMLAGQPPFDGEDE 360
Query: 245 IQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFG 283
+++ I V +P S + L + LL + TKR G
Sbjct: 361 DELFSSITDHNVSYPKAMSREAVSLCKGLLMKNPTKRLG 477
>27405
Length = 532
Score = 124 bits (310), Expect = 7e-29, Method: Compositional matrix adjust.
Identities = 64/177 (36%), Positives = 110/177 (62%), Gaps = 7/177 (3%)
Frame = -3
Query: 54 SFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEH-TLNEKRILQAVNF----PFLVKLE 108
FG V + +TG YAMK LDK+++ K+K E LNE+ +L V+ PF+V +
Sbjct: 530 GFGEVYGCRKADTGKMYAMKCLDKKRI-KMKGGETLALNERIMLSLVSTGEGSPFIVCMT 354
Query: 109 FSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDL 168
++F+ L +++ + GG++ HL + G F+E RFYAA+++L E++HS ++YRDL
Sbjct: 353 YAFQTPEKLCFILDLMNGGDLHYHLSQHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDL 174
Query: 169 KPENLLIDQQGYIQVTDFGFAKRV-KGRTWTLCGTPEYLAPEIIL-SKGYNKAVDWW 223
KP N+L+D+ G+++++D G A K + GT Y+APE+++ + Y+ + DW+
Sbjct: 173 KPANILLDENGHVRISDLGLACDFSKKKPHASVGTHGYMAPEVLMKGQAYDSSADWF 3
>00486
Length = 797
Score = 120 bits (301), Expect = 8e-28, Method: Compositional matrix adjust.
Identities = 54/134 (40%), Positives = 82/134 (61%)
Frame = -2
Query: 196 TWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGK 255
T T CGT EY+APEI+ G+ KAVDWW+LG L+Y+M G PPF A+ + +KI+ GK
Sbjct: 787 THTFCGTIEYMAPEILTRTGHGKAVDWWSLGALMYDMLTGSPPFTAENRKKTIDKILKGK 608
Query: 256 VRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPF 315
+ P + +++ + L++ LL+ + +R G + IK+H++F T+W + R+ E PF
Sbjct: 607 LNLPPYLTNEARGLIKKLLRKNPAERLGGGHDDSGPIKDHQFFRNTNWALLALRRAEPPF 428
Query: 316 IPKFKGPGDTSNFD 329
P DTS FD
Sbjct: 427 RPNVTSDEDTSQFD 386
>31885
Length = 529
Score = 115 bits (287), Expect = 3e-26, Method: Compositional matrix adjust.
Identities = 56/162 (34%), Positives = 96/162 (59%), Gaps = 7/162 (4%)
Frame = -2
Query: 95 ILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLT 154
+L ++ PFLV L ++F+D +L+MV++ GG++ H+++ F E +FY Q+ L
Sbjct: 513 MLTRLDHPFLVNLWYAFQDEEDLFMVVDLFLGGDLRYHMQQEVSFREDCVKFYLCQLALV 334
Query: 155 FEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGR--TWTLCGTPEYLAPEII- 211
+YL S +++RD+KP+N+L+D+QG+ VTDF A +++ + GT Y+APE+
Sbjct: 333 LDYLRSQKIVHRDIKPDNILLDEQGHCHVTDFNIATQLEDDELATSTSGTRPYMAPEVYG 154
Query: 212 ----LSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYE 249
+GY VDWW+LGV ++E+ PF ++E
Sbjct: 153 VAINERRGYGFPVDWWSLGVSLFELLKKRRPFSVHSNTSLHE 28
>15910
Length = 1361
Score = 114 bits (285), Expect = 6e-26, Method: Compositional matrix adjust.
Identities = 57/164 (34%), Positives = 96/164 (58%), Gaps = 9/164 (5%)
Frame = +2
Query: 128 EMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLL---IDQQGYIQVT 184
E+F + G+++E A + I+ +Y+H+ +++RDLKPENLL + +++
Sbjct: 422 ELFDRIVTRGQYTEKDAARAISDILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLA 601
Query: 185 DFGFAKRVKGRTW--TLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFAD 242
DFG ++ ++ T+CGTP Y APE++ Y +VD W++GV+ Y + GY PFFA+
Sbjct: 602 DFGLSRIIEPEVQMSTVCGTPGYCAPEVLKGDKYTPSVDMWSVGVIAYILLCGYEPFFAE 781
Query: 243 QPIQIYEKIVSGKVRFP----SHFSSDLKDLLRNLLQVDLTKRF 282
++Y KI+ G+ +F S S + KD++R LL +D KR
Sbjct: 782 NEFEMYRKIIKGEYKFDEEYWSEISENAKDVVRKLLVIDPKKRL 913
>18921
Length = 697
Score = 110 bits (276), Expect = 7e-25, Method: Compositional matrix adjust.
Identities = 67/203 (33%), Positives = 106/203 (52%), Gaps = 4/203 (1%)
Frame = +2
Query: 42 DQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNF 101
D F+ + LG GS+G V HKETG A+K +V ++ + E I+Q +
Sbjct: 29 DVFDILGKLGEGSYGSVFKSLHKETGQVLAIK-----QVPVDTDLQEIIKEISIMQQCDS 193
Query: 102 PFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLR-RIGRFSEPHARFYAAQIVLTFEYLHS 160
++VK S+ N++L++VMEY G + +R R E + YLHS
Sbjct: 194 KYIVKYYGSYFKNTDLWIVMEYCGAGSVSDIMRLRNKTLVEREIATILYYTLKGLXYLHS 373
Query: 161 LDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVK---GRTWTLCGTPEYLAPEIILSKGYN 217
I+RD+K N+L++ +G+ ++ DFG A ++ + T+ GTP ++APE+I GY+
Sbjct: 374 RRKIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTPYWMAPEVIQEIGYD 553
Query: 218 KAVDWWALGVLIYEMAAGYPPFF 240
D W+LG+ EMA G PP
Sbjct: 554 CVADIWSLGITALEMAEGKPPVM 622
>12721
Length = 821
Score = 110 bits (274), Expect = 1e-24, Method: Compositional matrix adjust.
Identities = 73/255 (28%), Positives = 129/255 (50%), Gaps = 6/255 (2%)
Frame = +1
Query: 33 SPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNE 92
+P LD F +I G GS G V + ++ G A+K +D +K ++ E NE
Sbjct: 70 TPGDPRTFLDDFMKI---GEGSTGIVCIATSRD-GRQMAVKKMDLRK---QQRRELLFNE 228
Query: 93 KRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIV 152
+++ + P +V++ S+ N L++VME++ GG + + + R E +
Sbjct: 229 VVVMRDYHHPNIVEMYNSYLVNDELWVVMEFMEGGAL-TDIVTNNRMDEVQIATVCRACL 405
Query: 153 LTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKG---RTWTLCGTPEYLAPE 209
+LH+ +I+RD+K +++L+ G +++ DFGF +V + +L GTP ++APE
Sbjct: 406 KALAFLHANGVIHRDIKSDSILLSHDGKVKLXDFGFCAQVTQDLQKRKSLVGTPYWMAPE 585
Query: 210 IILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKI---VSGKVRFPSHFSSDL 266
+I Y VD W+LG+++ EM PPFF + P+Q +I K+R S L
Sbjct: 586 VISRLPYGPEVDIWSLGIMVMEMIDAEPPFFNEPPLQAMRRIRDMPPPKLRNTHKISPRL 765
Query: 267 KDLLRNLLQVDLTKR 281
+ + +L D +R
Sbjct: 766 QGFIDRMLVRDPHQR 810
>09606
Length = 1300
Score = 102 bits (253), Expect = 3e-22, Method: Compositional matrix adjust.
Identities = 69/275 (25%), Positives = 123/275 (44%), Gaps = 33/275 (12%)
Frame = -3
Query: 41 LDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVN 100
++ F + LG G + + K T N A+ ++K K ++ N R+ ++
Sbjct: 1118 MENFVLYEELGKGEHSIIYKGRRKGTINFVAIHCIEKCKRPEVT------NTVRMTHDIS 957
Query: 101 FPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHS 160
P +V+ ++ +++L++V+E GG + L + E R + +V Y+HS
Sbjct: 956 HPNVVQFHEWYETSNHLWLVVELCTGGSLADILAQDHHLPETSIRDFGIHLVTGLHYIHS 777
Query: 161 LDLIYRDLKPENLLIDQQGYIQVTDFGFAK-------------RVKGRTWTL-------- 199
L +++ DL+P +L+D G ++ DFG +K G W +
Sbjct: 776 LGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQWNIQSAEEMMK 597
Query: 200 ----CGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGK 255
G+P Y+APE+ + D WALG + YEM +G+PPF + +K+++ +
Sbjct: 596 QVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSGHPPFLGETYDITKDKVLNKE 417
Query: 256 VRFPSHFSSDLK--------DLLRNLLQVDLTKRF 282
P S L +LL +LLQ D T+R
Sbjct: 416 FPLPKVKGSRLSAKPSPEFLNLLESLLQKDSTRRL 312
>26560
Length = 398
Score = 101 bits (252), Expect = 4e-22, Method: Compositional matrix adjust.
Identities = 43/114 (37%), Positives = 76/114 (66%), Gaps = 2/114 (1%)
Frame = -1
Query: 128 EMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFG 187
++ HL + G F+E RFYAA+++L E++HS ++YRDLKP N+L+D+ G+++++D G
Sbjct: 398 DLHYHLSQHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLG 219
Query: 188 FAKRV-KGRTWTLCGTPEYLAPEIIL-SKGYNKAVDWWALGVLIYEMAAGYPPF 239
A K R GT Y+APE+++ + Y+ + DW++ G ++Y++ G+ PF
Sbjct: 218 LACDFSKKRPHASVGTHGYMAPEVLMKGQSYDSSADWFSFGCMLYKLLKGHSPF 57
>01707
Length = 757
Score = 100 bits (248), Expect = 1e-21, Method: Compositional matrix adjust.
Identities = 64/201 (31%), Positives = 109/201 (54%), Gaps = 6/201 (2%)
Frame = +1
Query: 41 LDQFERIKTLGTGSFGRVMLVKHKETGNHYAMK-ILDKQKVVKLKQIEHTLNEKRILQAV 99
++++E+I +G GS+G V ++KET A+K ++ + +K+I + E R+L+ +
Sbjct: 61 MEKYEKIGKIGEGSYGVVFKCRNKETSQLVAIKKFVESEDDPLIKKI--AMREIRMLKQL 234
Query: 100 NFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGR-FSEPHARFYAAQIVLTFEYL 158
P LV+L F+ L++V +YV + + L R R EP + Q +L +
Sbjct: 235 KHPNLVRLIEVFRRKKRLHLVFDYV-DHTLLNELDRYPRGLPEPMVKRIIYQTLLAVNFC 411
Query: 159 HSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKG---RTWTLCGTPEYLAPEIILSKG 215
H + I+RD+KPEN+LI +QG +++ DFGFA+ + G T Y APE+++
Sbjct: 412 HQYNTIHRDVKPENILITRQGQVKLCDFGFARILTGPGDEYTDYVATRWYRAPELLVGDT 591
Query: 216 -YNKAVDWWALGVLIYEMAAG 235
Y VD WA+G + E+ G
Sbjct: 592 QYGPPVDVWAIGCVFAELLTG 654
>00300
Length = 2318
Score = 99.0 bits (245), Expect = 3e-21, Method: Compositional matrix adjust.
Identities = 72/250 (28%), Positives = 118/250 (47%), Gaps = 11/250 (4%)
Frame = -1
Query: 43 QFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFP 102
+++R +G G FG+V + TG A+K + Q L+Q+ +E +I + +
Sbjct: 1655 RWQRGNKIGEGQFGKVYTAVNMSTGELMALKEMKFQPN-DLQQLREMCDEIKIFEGIQHE 1479
Query: 103 FLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLD 162
LVK + M MEY G + ++G E R Y +IVL +LH
Sbjct: 1478 NLVKYYGVEVHKDEMLMFMEYCDTGTI-EEAAKMG-LPEYLIRRYTREIVLAVNHLHENS 1305
Query: 163 LIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRT------WTLCGTPEYLAPEIILSK-- 214
+++RD+K N+ + G++++ DFG + ++K T L GT Y+APE+
Sbjct: 1304 IVHRDIKGANIFLTSNGHVKLGDFGCSVKLKSHTTMPGEFHNLVGTTAYMAPEVFTQNDQ 1125
Query: 215 -GYNKAVDWWALGVLIYEMAAGYPPFF-ADQPIQIYEKI-VSGKVRFPSHFSSDLKDLLR 271
GY +A D W+LG ++ EMA G P+ D QI K+ + K P S + K L
Sbjct: 1124 GGYGRAADIWSLGCVVIEMATGKRPWHDLDNNYQIMYKVGIGHKPAVPDSLSVEGKHFLD 945
Query: 272 NLLQVDLTKR 281
++ D +R
Sbjct: 944 LIMCHDPAQR 915
>14420
Length = 528
Score = 98.6 bits (244), Expect = 3e-21, Method: Compositional matrix adjust.
Identities = 49/163 (30%), Positives = 88/163 (53%), Gaps = 3/163 (1%)
Frame = +2
Query: 87 EHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARF 146
E +NE +++ P +V S+ L++VME++ GG + + E
Sbjct: 35 ELIINEILVMRENQNPNIVNYLDSYLVGEELWVVMEFLAGGSLTDVVTETC-MDEGQIAA 211
Query: 147 YAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRV---KGRTWTLCGTP 203
+ + E+LH +I+RD+K +N+L+ G +++TDFGF ++ + + T+ GTP
Sbjct: 212 VCRECLQALEFLHENQVIHRDIKSDNILLGMDGSVKLTDFGFCAQLSPEQSKRSTMVGTP 391
Query: 204 EYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQ 246
++APE++ K Y VD W+LGV+ EM G PP+ + P++
Sbjct: 392 YWMAPEVVTRKQYGPTVDIWSLGVMCIEMIEGEPPYLNENPLR 520
>18663
Length = 600
Score = 97.4 bits (241), Expect = 8e-21, Method: Compositional matrix adjust.
Identities = 51/141 (36%), Positives = 76/141 (53%), Gaps = 10/141 (7%)
Frame = +2
Query: 198 TLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPF----FADQPIQ-----IY 248
T CGTP Y+APEI+ + Y +VDWWALGVL+YEM AG PF ++ P Q ++
Sbjct: 5 TFCGTPNYIAPEILRGEDYGFSVDWWALGVLLYEMLAGRSPFDIAGASENPDQNTEDYLF 184
Query: 249 EKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFG-NLKNGVNDIKNHKWFATTDWIAIY 307
+ I+ +R P S +L+ L + R G + ++ DI NH +F DW +
Sbjct: 185 QVILEKTIRIPRSLSVKAASVLKGFLNKNPADRLGCHRESAFMDIVNHPFFKVIDWEMLE 364
Query: 308 QRKVEAPFIPKFKGPGDTSNF 328
+++V PF P+ D +NF
Sbjct: 365 RKQVSPPFKPRLDSDRDLANF 427
>13592
Length = 980
Score = 93.2 bits (230), Expect = 2e-19, Method: Compositional matrix adjust.
Identities = 68/249 (27%), Positives = 118/249 (47%), Gaps = 12/249 (4%)
Frame = +2
Query: 50 LGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEF 109
+G G FG+V + TG AMK + Q + + +++ E +IL+ + LV+
Sbjct: 8 IGQGRFGKVYTAVNNNTGELMAMKEIAIQPG-ETRALKNVAEELKILEGIKHKNLVRYYG 184
Query: 110 SFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLK 169
L + ME G + S + G E +R + AQ++ LH +++RD+K
Sbjct: 185 IEVHREELLIFMELCSEGTLESLVELTGGLPEALSRRFTAQLLSGVAELHKHGIVHRDIK 364
Query: 170 PENL-LIDQQGYIQVTDFGFAKRVKGRTWT------LCGTPEYLAPEIIL---SKGYNKA 219
N+ L+D +++ DFG A +++ T GT Y+APE+ S G+ +
Sbjct: 365 TANIFLVDGSNSLKLGDFGSAVKIQAHTTVPGELQGYVGTQAYMAPEVFTKTNSDGHGRL 544
Query: 220 VDWWALGVLIYEMAAGYPPFFA-DQPIQIYEKIVSG-KVRFPSHFSSDLKDLLRNLLQVD 277
D W++G ++ EMA+G P+ D QI K+ G K + P S + D + + LQ D
Sbjct: 545 ADIWSVGCVVVEMASGKRPWAQFDSNFQIMFKVGMGEKPQAPESLSQEGHDFIDHCLQHD 724
Query: 278 LTKRFGNLK 286
+R ++
Sbjct: 725 PKQRLSAIE 751
>26156
Length = 479
Score = 82.4 bits (202), Expect(2) = 2e-19, Method: Compositional matrix adjust.
Identities = 43/112 (38%), Positives = 67/112 (59%), Gaps = 1/112 (0%)
Frame = -1
Query: 36 QNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRI 95
+N L F ++ +G GS+ +V+ V+HK T YAMK++ K+ V + I+ EK +
Sbjct: 407 RNKLGLTDFLLLRVIGRGSYAKVLQVEHKRTKRIYAMKVIKKELVNDDEDIDWVQTEKHV 228
Query: 96 LQ-AVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARF 146
+ A N+PFLV L F+ S L+ V+E+V GG++ H++R R E HARF
Sbjct: 227 FETATNYPFLVGLHSCFQSESRLFFVIEFVNGGDLMFHMQRQRRLPEEHARF 72
Score = 30.8 bits (68), Expect(2) = 2e-19, Method: Compositional matrix adjust.
Identities = 12/24 (50%), Positives = 17/24 (70%)
Frame = -3
Query: 146 FYAAQIVLTFEYLHSLDLIYRDLK 169
FY+A+I L +LH ++YRDLK
Sbjct: 75 FYSAEICLALNFLHKRGIVYRDLK 4
>01392
Length = 1806
Score = 92.0 bits (227), Expect = 3e-19, Method: Compositional matrix adjust.
Identities = 60/199 (30%), Positives = 88/199 (44%), Gaps = 35/199 (17%)
Frame = -1
Query: 137 GRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLL---IDQQGYIQVTDFGFAKRVK 193
G E A I ++LHS + +RDLKPEN+L +D +++ DF A +
Sbjct: 1806 GHLCEREASLVVRHIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGIS 1627
Query: 194 G--------RTWTLCGTPEYLAPEIIL-----SKGYNKAVDWWALGVLIYEMAAGYPPFF 240
T G+ EY+APE++ S Y+K D W+LG+++Y M GYPPF+
Sbjct: 1626 CDGDGTKTPELLTPVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILYIMLCGYPPFY 1447
Query: 241 A---------------DQPIQIYEKIVSGKVRFPSH----FSSDLKDLLRNLLQVDLTKR 281
D ++ I G +FPS SS KDL+R+LL + KR
Sbjct: 1446 GQCGEDCGWNRGEACHDCQDMLFNSIQDGHYKFPSQEWTSISSSAKDLIRHLLVREPRKR 1267
Query: 282 FGNLKNGVNDIKNHKWFAT 300
+ D+ H W T
Sbjct: 1266 Y-----SAADVLKHPWICT 1225
>17975
Length = 449
Score = 85.5 bits (210), Expect = 3e-17, Method: Compositional matrix adjust.
Identities = 48/137 (35%), Positives = 80/137 (58%), Gaps = 2/137 (1%)
Frame = +3
Query: 55 FGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDN 114
F V L +H TG A+K++DK K+ ++ + H E R ++ V P +V+L
Sbjct: 6 FAVVKLARHVFTGEKVAVKVIDKTKLDEVSR-SHLFQEVRCMKLVQHPNVVRLYEVIDTQ 182
Query: 115 SNLYMVMEYVPGGEMFSH-LRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENL 173
+ LY+++E GG+M+ + +R G E A+ Y QIV Y H L +++RDLKPEN+
Sbjct: 183 TKLYLILELGDGGDMYDYIMRHSGGLEEKLAKRYFRQIVEAISYCHKLHVVHRDLKPENV 362
Query: 174 L-IDQQGYIQVTDFGFA 189
+ ++ G +++TDFGF+
Sbjct: 363 VFFEKPGLVKLTDFGFS 413
>13066
Length = 551
Score = 84.0 bits (206), Expect = 9e-17, Method: Compositional matrix adjust.
Identities = 48/164 (29%), Positives = 85/164 (51%), Gaps = 8/164 (4%)
Frame = +3
Query: 71 AMKILDKQKVVKLKQIEHTL-NEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEM 129
A KI+DK+K + +E E +L ++ P+++++ + ++ M + G++
Sbjct: 63 ACKIIDKEKA-PVDFVEKFFPRELDLLTKLDHPYIIQIHSILQRXPKNFIFMRFAERGDL 239
Query: 130 FSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFA 189
++++ +G E A+ + Q+ YLHS D+ +RDLK EN+L+ +++ DFGFA
Sbjct: 240 LTYIQEVGFVKEKQAKIWFYQMTTALNYLHSYDVAHRDLKCENILLSSHFNVKLADFGFA 419
Query: 190 KRV------KGRTWTLCGTPEYLAPEIILSKGYN-KAVDWWALG 226
K + T CG+ Y APEI+ Y K D W+LG
Sbjct: 420 CACITESGEKYMSRTYCGSAAYAAPEIVYGAPYAPKVADAWSLG 551
>06405
Length = 1965
Score = 83.6 bits (205), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 70/240 (29%), Positives = 110/240 (45%), Gaps = 8/240 (3%)
Frame = +1
Query: 50 LGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEF 109
LG G +G V K A+K L K+ + L L E I++ + P LV+L
Sbjct: 283 LGGGQYGDVYEAMWKRYNKIVAVKTL-KEDTMALNDF---LEEAAIMKEMKHPNLVQLLG 450
Query: 110 SFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSE-PHARFY-AAQIVLTFEYLHSLDLIYRD 167
Y+V E++P G + +LR R P A Y A QI YL + + I+RD
Sbjct: 451 VCTREPPFYIVTEFMPHGNLLDYLRSSTREENGPTALMYMATQIASGMAYLETKNFIHRD 630
Query: 168 LKPENLLIDQQGYIQVTDFGFAKRVKGRTWTL-CGTP---EYLAPEIILSKGYNKAVDWW 223
L N L+ ++V DFG A+ +K T+T G ++ APE + ++ D W
Sbjct: 631 LAARNCLVADSNMVKVADFGLARLMKDDTYTAHIGAKFPIKWTAPEGLAFNRFSTRSDIW 810
Query: 224 ALGVLIYEMAA-GYPPFFADQPIQIYEKIVSG-KVRFPSHFSSDLKDLLRNLLQVDLTKR 281
A GVL++E+A G P+ + ++Y + G ++ P +D+ L+ Q D R
Sbjct: 811 AFGVLLWELATYGMSPYPGVELTEVYHLLERGYRMERPPGTPADVYILMLKCWQWDPKDR 990
>01060
Length = 1800
Score = 81.3 bits (199), Expect = 6e-16, Method: Compositional matrix adjust.
Identities = 67/234 (28%), Positives = 110/234 (47%), Gaps = 21/234 (8%)
Frame = +1
Query: 39 AHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIE-----HTLNEK 93
+ L F++I G G++G V +H+ TG AMK ++L+ E + E
Sbjct: 73 SDLTDFQKI---GEGTYGVVYKCRHRATGRKLAMK------KIRLRGSEDGVPSSAIREI 225
Query: 94 RILQAVNFPFLVKLEFSFKDNSNLYMVMEYV-----------PGGEMFSHLRRIGRFSEP 142
+L+ + +V LE ++ L++V E++ P G + RR+
Sbjct: 226 AMLRELRHTNIVCLEDVIMEDERLFLVFEFLSMDLKMYIDKFPEGVVLD--RRL------ 381
Query: 143 HARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKR----VKGRTWT 198
+ Y QIV + H +++RDLKP+NLLI+ G I++ DFG A+ V+ T
Sbjct: 382 -VKSYVFQIVTGIXFCHQRRIVHRDLKPQNLLINHTGAIKIADFGMARTFALPVRAYTHE 558
Query: 199 LCGTPEYLAPEIIL-SKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKI 251
+ T Y APEI++ + Y+ VD W++G + +M P F D I KI
Sbjct: 559 VV-TLWYRAPEILMGASKYSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKI 717
>21079
Length = 878
Score = 80.5 bits (197), Expect = 8e-16, Method: Compositional matrix adjust.
Identities = 47/142 (33%), Positives = 75/142 (52%), Gaps = 5/142 (3%)
Frame = +1
Query: 102 PFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIG-RFSEPHARFYAAQIVLTFEYLHS 160
P L+ L +F+ + +VME+V GE+F + R +E + QI Y+H+
Sbjct: 4 PKLLMLWDAFEAPRTMVLVMEFVGAGELFERVIRDDFVLTERDCVHFVRQICSGVGYMHT 183
Query: 161 LDLIYRDLKPENLLI--DQQGYIQVTDFGFAKRVK--GRTWTLCGTPEYLAPEIILSKGY 216
+++ DLKPEN+L D I++ DFG A+ K L GTPE++APE++
Sbjct: 184 QSILHLDLKPENVLCVSDNSNQIKIIDFGLARFYKPGDSLQVLFGTPEFIAPEVVNYDEI 363
Query: 217 NKAVDWWALGVLIYEMAAGYPP 238
N D W++GV+ Y + +G P
Sbjct: 364 NFTTDMWSIGVICYILLSGLSP 429
>21433
Length = 590
Score = 78.2 bits (191), Expect = 5e-15, Method: Compositional matrix adjust.
Identities = 46/130 (35%), Positives = 69/130 (53%), Gaps = 1/130 (0%)
Frame = +2
Query: 147 YAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRV-KGRTWTLCGTPEY 205
Y Q+ EY H +I+RD+KPENLL+ +G +++ DFG++ R T+CGT +Y
Sbjct: 182 YIYQLSSALEYCHYRKVIHRDIKPENLLLGLKGDLKIADFGWSVHAPSSRRTTMCGTLDY 361
Query: 206 LAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSD 265
L PE++ K +++ VD W+LGVL YE G PP PS +
Sbjct: 362 LPPEMVEGKTHDENVDLWSLGVLCYEFLVGTPPLRPSPTRPPTPASPRWTSGSPSIVTPG 541
Query: 266 LKDLLRNLLQ 275
+DL+ LL+
Sbjct: 542 ARDLISKLLR 571
>17722
Length = 680
Score = 75.5 bits (184), Expect = 3e-14, Method: Compositional matrix adjust.
Identities = 37/106 (34%), Positives = 56/106 (52%)
Frame = -3
Query: 220 VDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLT 279
VDWW GV++YEM G PF+ ++E I+ V+FP + S + K LL LL +
Sbjct: 678 VDWWGTGVVMYEMMCGRLPFYNRDHDVLFELILLQNVKFPRNLSEEAKTLLSGLLAKNPK 499
Query: 280 KRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDT 325
+R G + V +IK H +F +W + +K+ P+ P K DT
Sbjct: 498 RRLGGSEADVTEIKTHPFFQCINWDDLAAKKITPPWKPDVKSSWDT 361
>01756
Length = 1858
Score = 73.9 bits (180), Expect = 9e-14, Method: Compositional matrix adjust.
Identities = 55/212 (25%), Positives = 104/212 (49%), Gaps = 17/212 (8%)
Frame = -3
Query: 43 QFERIKTLGTGSFGRVMLVKHKETGNHYAMK--ILDKQK----VVKLKQIE--HTLNEKR 94
++E++ +G G+FG V + K+T AMK ++D +K + L++I+ LN +
Sbjct: 1739 KYEKLAKIGQGTFGEVFKARCKKTKQVVAMKKVLMDNEKEGFPITALREIKILQLLNHEN 1560
Query: 95 ILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPG--GEMFSHLRRIGRFSEPHARFYAAQIV 152
++ + K + + S Y+V E+ + S++ + F+ P + Q++
Sbjct: 1559 VVDLIEI-CSTKATSANRYKSMFYLVFEFCEHDLAGLLSNMSVV--FNLPEIKEVMKQLM 1389
Query: 153 LTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAK------RVKGRTWTLCGTPEYL 206
Y+H +++RD+K N+LI +QG +++ DFG A+ R R T Y
Sbjct: 1388 NGLYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYR 1209
Query: 207 APEIILS-KGYNKAVDWWALGVLIYEMAAGYP 237
PE++L + Y+ A+D W G ++ EM P
Sbjct: 1208 PPELLLGDRNYSTAIDQWGAGCIMAEMWTRNP 1113
>00392
Length = 668
Score = 72.4 bits (176), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 50/177 (28%), Positives = 99/177 (55%), Gaps = 14/177 (7%)
Frame = +3
Query: 92 EKRILQAVNFPFLVKL-----EFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARF 146
E +L+ + P +V+ E + ++ + +V E + G + ++L+R F +P+ +
Sbjct: 81 EAEMLKELQHPNIVRFFDYWEEHNHRNRKVIILVTELMTSGTLKTYLKR---FKKPNVKI 251
Query: 147 ---YAAQIVLTFEYLHSLD--LIYRDLKPENLLID-QQGYIQVTDFGFAKRVKGRTW--T 198
+ Q++ +LH+ +I+RDLK +N+ I G +++ D G A +K +++ +
Sbjct: 252 LKNWCRQVLKGLYFLHTRTPPVIHRDLKCDNIFITGPTGSVKIGDLGLAT-LKNQSFAKS 428
Query: 199 LCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAG-YPPFFADQPIQIYEKIVSG 254
+ GTPE++APE+ + Y++AVD +A G+ + EMA+ YP QIY+++ SG
Sbjct: 429 VIGTPEFMAPEM-YEEHYDEAVDVYAFGMCMLEMASSEYPYSECSNAAQIYKRVTSG 596
>27546
Length = 426
Score = 71.2 bits (173), Expect = 6e-13, Method: Compositional matrix adjust.
Identities = 30/102 (29%), Positives = 59/102 (57%)
Frame = -1
Query: 92 EKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQI 151
E IL ++ P ++++ + +++ M Y G+M SH+++ G E + + Q+
Sbjct: 330 ELEILTRLDHPNIIQIHSILQRGPKIFIFMRYAEKGDMLSHIKKTGPIDEAQTKVWFFQM 151
Query: 152 VLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVK 193
+YLHS D+ +RDLK EN+L+ ++ +++ DFGFA+ +
Sbjct: 150 AKALQYLHSHDIAHRDLKCENILLSKRLNVKIADFGFARYCR 25
>09007
Length = 1440
Score = 70.9 bits (172), Expect = 7e-13, Method: Compositional matrix adjust.
Identities = 59/220 (26%), Positives = 102/220 (46%), Gaps = 16/220 (7%)
Frame = -1
Query: 48 KTLGTGSFGRV-MLVKHKETGN--HYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFL 104
K+LG G FG V + E+G A+K L K K+ K Q L E I+Q ++ +
Sbjct: 861 KSLGQGHFGTVRQAIWTAESGEKVQVAVKCLSKDKIHKDGQ--EFLKETAIMQMLDHENI 688
Query: 105 VKLEFSFKDN-SNLYMVMEYVPGGEMFSHLRRIGR---FSEPHARFYAAQIVLTFEYLHS 160
V++ DN +++ +V E P + ++ + FS P ++ Q+ YL S
Sbjct: 687 VRVYGVVMDNGADIMLVTELAPMRSLLECVKEVSARVDFSVPRLCDFSQQVCDGMSYLES 508
Query: 161 LDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKG--------RTWTLCGTPEYLAPEIIL 212
L++RDL N+L+ + ++++D G + + +T L + APE
Sbjct: 507 KRLVHRDLAARNILLFSKSKVKISDVGVSGALGAGKEYYQSQQTIHLQNAVAWCAPESFR 328
Query: 213 SKGYNKAVDWWALGVLIYE-MAAGYPPFFADQPIQIYEKI 251
+ ++ A D WA GVL++E G+ P+ QI E +
Sbjct: 327 NLCFSSASDVWAFGVLLWEFFTHGFQPWAGLNGQQIMEAV 208
>19094
Length = 898
Score = 69.3 bits (168), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 33/82 (40%), Positives = 52/82 (63%), Gaps = 3/82 (3%)
Frame = +1
Query: 157 YLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVK---GRTWTLCGTPEYLAPEIILS 213
YLHS I+RD+K N+L++ +G+ ++ DFG A ++ + T+ GTP ++APE+I
Sbjct: 103 YLHSRRKIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTPYWMAPEVIQE 282
Query: 214 KGYNKAVDWWALGVLIYEMAAG 235
GY+ D W+LG+ EMA G
Sbjct: 283 IGYDCVADIWSLGITALEMAEG 348
>25019
Length = 730
Score = 69.3 bits (168), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 31/59 (52%), Positives = 43/59 (72%), Gaps = 3/59 (5%)
Frame = +3
Query: 171 ENLLIDQQGYIQVTDFGFAKR-VKGR--TWTLCGTPEYLAPEIILSKGYNKAVDWWALG 226
EN+L+D+ G++++TDFG K + G T T CGT EY+APEI+ G+ KAVDWW+LG
Sbjct: 261 ENVLLDKDGHVKLTDFGLCKEAITGTRVTHTFCGTIEYMAPEILTRTGHGKAVDWWSLG 437
Score = 47.8 bits (112), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 23/74 (31%), Positives = 41/74 (55%), Gaps = 4/74 (5%)
Frame = +1
Query: 214 KGYNKAVDW----WALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDL 269
+G A W W G L+Y+M G PPF A+ + +KI+ GK+ P + +++ + L
Sbjct: 394 RGQGTARRWTGGVW--GALMYDMLTGSPPFTAENRKKTIDKILKGKLNLPPYLTNEARGL 567
Query: 270 LRNLLQVDLTKRFG 283
++ LL+ + +R G
Sbjct: 568 IKKLLRKNPAERLG 609
>01718
Length = 959
Score = 68.6 bits (166), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 58/212 (27%), Positives = 99/212 (46%), Gaps = 15/212 (7%)
Frame = +3
Query: 41 LDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVN 100
LD F + +G G F V V H+ TG A+K+ + L E ++L +
Sbjct: 147 LDDF-ICEKIGAGFFSEVFKVTHRITGQVMALKM-----NTMTSNRHNMLREVQLLNRLQ 308
Query: 101 FPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTF----- 155
+++ L+ + EY+P G + L + + + +I LT
Sbjct: 309 HANILRFMGVCVHEGQLHALTEYIPSGNLEQLLEK-----KDEELPWTQRIQLTLGLARG 473
Query: 156 -EYLHSLDLIYRDLKPENLLI---DQQGYIQV-TDFGFAKRV-----KGRTWTLCGTPEY 205
+YLHS I+RDL +N+LI D GY V DFG A ++ K + T+ G+P +
Sbjct: 474 LDYLHSTRFIHRDLTSKNILIRREDNHGYHAVIADFGLATKIPDPLDKEKLPTV-GSPYW 650
Query: 206 LAPEIILSKGYNKAVDWWALGVLIYEMAAGYP 237
+APE++ YN+ D +++G+++ E+ A P
Sbjct: 651 MAPEVLNGHFYNERADLFSVGIIMCEITARIP 746
>19761
Length = 473
Score = 68.2 bits (165), Expect = 4e-12, Method: Compositional matrix adjust.
Identities = 34/128 (26%), Positives = 68/128 (53%), Gaps = 3/128 (2%)
Frame = -3
Query: 153 LTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGR---TWTLCGTPEYLAPE 209
L + + H+ +++RDLKP+N+ + ++G +++ D G A+++ G + GT YL+PE
Sbjct: 384 LNYMHTHTPVILHRDLKPQNIYVTEKGDVRLGDLGLARKLTGPADFATSQVGTIMYLSPE 205
Query: 210 IILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDL 269
I+ + YN D W+LG + Y++ + + + K+ P H+S + +D
Sbjct: 204 ILSQQPYNSKSDIWSLGCVFYDITGKKGSDEMGVMFLLVQVMGGRKLPLPDHYSQEFRDT 25
Query: 270 LRNLLQVD 277
+ +L D
Sbjct: 24 ISRMLTKD 1
>26711
Length = 405
Score = 67.8 bits (164), Expect = 6e-12, Method: Compositional matrix adjust.
Identities = 41/130 (31%), Positives = 70/130 (53%), Gaps = 9/130 (6%)
Frame = -2
Query: 150 QIVLTFEYLHSLDLIYRDLKPENLLI--DQQGYIQVTDFGFAKRV--KGRTWTLCGTPEY 205
Q++ +++H+ +++ DLKP NLL+ D+ +Q+ DFG A+++ T+ GTP +
Sbjct: 392 QVLDILQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARKLYPPQETFLNHGTPGF 213
Query: 206 LAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFP-----S 260
+PE + K + A D W +GVL Y + +G PF AD + +K + F S
Sbjct: 212 TSPEALDVKPISTASDVWGVGVLAYILLSGQSPFQADSATESLKKTQTCDWSFDVCPSFS 33
Query: 261 HFSSDLKDLL 270
+ S D KD +
Sbjct: 32 NMSQDAKDFI 3
>11185
Length = 473
Score = 65.9 bits (159), Expect = 3e-11, Method: Compositional matrix adjust.
Identities = 43/163 (26%), Positives = 67/163 (41%), Gaps = 25/163 (15%)
Frame = +1
Query: 145 RFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAK-------------R 191
R + +V Y+HSL +++ DL+P +L+D G ++ DFG +K
Sbjct: 10 RDFGIHLVTGLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFA 189
Query: 192 VKGRTWTL------------CGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPF 239
G W + G+P Y+APE+ + D WALG + YEM +G
Sbjct: 190 EAGDQWNIQSAEEMMKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSG---- 357
Query: 240 FADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRF 282
R + S + +LL +LLQ D T+R
Sbjct: 358 ----------------SRLSAKPSPEFLNLLESLLQKDSTRRL 438
>38560
Length = 479
Score = 65.1 bits (157), Expect = 4e-11, Method: Compositional matrix adjust.
Identities = 38/131 (29%), Positives = 60/131 (45%), Gaps = 6/131 (4%)
Frame = -3
Query: 198 TLCGTPEYLAPEIILSKGY-NKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKV 256
T CG+P Y APE+I Y D W++GVL+Y + GY PF ++ + +K K
Sbjct: 408 TCCGSPAYAAPELISGLEYLGSEADIWSMGVLLYALLCGYLPFDDEKXSHL*QKNQKRKD 229
Query: 257 RFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWF-----ATTDWIAIYQRKV 311
P S D LL +LQ D + R + + +H W +W + Y+R +
Sbjct: 228 EVPEWLSEDTTKLLEGMLQTDPSHRI-----TIRRLLDHHWLNQGFNVPVEWASKYKRTL 64
Query: 312 EAPFIPKFKGP 322
+ + + GP
Sbjct: 63 DEDCLTEAGGP 31
>13212
Length = 1067
Score = 64.3 bits (155), Expect = 8e-11, Method: Compositional matrix adjust.
Identities = 34/121 (28%), Positives = 64/121 (52%), Gaps = 8/121 (6%)
Frame = -1
Query: 139 FSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKR---VKGR 195
+E + ++ + ++LH +I+RD+K N+L+ G +++ DFG + + + +
Sbjct: 989 MTEAQICYVCHEMCMALDFLHRHHVIHRDIKAGNVLLTIDGEVKLADFGVSAKNTQTQQK 810
Query: 196 TWTLCGTPEYLAPEIILSKG-----YNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEK 250
T GTP ++APE++L + Y+ D W+LGV + E A PP P+++ K
Sbjct: 809 RDTFIGTPYWMAPEVVLCETLKDTPYDFKADIWSLGVTLIEFAQIEPPNKEMHPMRVLIK 630
Query: 251 I 251
I
Sbjct: 629 I 627
>29581
Length = 1278
Score = 63.9 bits (154), Expect = 8e-11, Method: Compositional matrix adjust.
Identities = 45/148 (30%), Positives = 75/148 (50%), Gaps = 7/148 (4%)
Frame = -2
Query: 112 KDNSNLYMVMEYVPGGEMFSHLRRI-GRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKP 170
K +L++VMEY ++ S L + FSE + Q++ YLH +I+RDLK
Sbjct: 1139 KSLDSLFLVMEYC-EQDLASLLDNMPAPFSESQVKCIVLQLLKGLRYLHEAFIIHRDLKV 963
Query: 171 ENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPE-----YLAPEIIL-SKGYNKAVDWWA 224
NLL+ +G +++ DFG A+ + TP+ Y APE++ SK ++ A+D W+
Sbjct: 962 SNLLMTDKGCVKIADFGLARNYGKPQKPM--TPKVVTLWYRAPELLFGSKTHSTAIDMWS 789
Query: 225 LGVLIYEMAAGYPPFFADQPIQIYEKIV 252
G ++ E+ P +Q E I+
Sbjct: 788 AGCILGELLGHKPLMPGRSDLQQIELIM 705
>28638
Length = 1458
Score = 63.9 bits (154), Expect = 9e-11, Method: Compositional matrix adjust.
Identities = 32/100 (32%), Positives = 59/100 (59%), Gaps = 4/100 (4%)
Frame = -1
Query: 144 ARFYAAQIVLTFEYLHS--LDLIYRDLKPENLLI--DQQGYIQVTDFGFAKRVKGRTWTL 199
R +A Q+ +L + +++I+ DLKPEN+L+ ++ I++ DFG + ++ R +
Sbjct: 831 TRKFAQQLCTALLFLATPEMNIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQY 652
Query: 200 CGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPF 239
+ Y +PE++L Y+ A+D W+LG ++ EM G PP
Sbjct: 651 IQSRFYRSPEVLLGVPYDLAIDMWSLGCILVEMHTGEPPL 532
>28157
Length = 400
Score = 63.2 bits (152), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 44/124 (35%), Positives = 68/124 (54%), Gaps = 13/124 (10%)
Frame = +3
Query: 79 KVVKLKQIEHTLNEKRILQA------VNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSH 132
K V +K+IE +K +Q V+ P +V L + +D+ + +VMEY GG +++
Sbjct: 3 KDVAVKRIESEQEKKSFMQELKQLSRVSHPNIVCLYGACRDHP-VCLVMEYAEGGSLYNV 179
Query: 133 LRRIG---RFSEPHARFYAAQIVLTFEYLHSLD---LIYRDLKPENLLIDQQGY-IQVTD 185
L G +++ HA + Q L EYLH + LI+RDLKP NLL+ Q G +++ D
Sbjct: 180 LHGSGPQPQYTAAHAMNWLLQCALGVEYLHGMKPKALIHRDLKPPNLLLIQCGTKLKICD 359
Query: 186 FGFA 189
FG A
Sbjct: 360 FGTA 371
>14126
Length = 1265
Score = 62.0 bits (149), Expect = 3e-10, Method: Compositional matrix adjust.
Identities = 50/204 (24%), Positives = 99/204 (48%), Gaps = 14/204 (6%)
Frame = +3
Query: 43 QFERIKTLGTGSFGRVMLVKH-KETGNHYAMKIL---DKQKVVKLKQIEHTLNEKRILQA 98
++E + +G G++G V + + G AMK + + ++ + + I K+ L+
Sbjct: 192 KYEEVAVIGNGAYGTVYKARDLRNQGEFVAMKRIRLNNTEEGMPMMAIREISMLKQ-LEQ 368
Query: 99 VNFPFLVKLEFSFKDNS------NLYMVMEYVPGGEMFSHLRRIGR--FSEPHARFYAAQ 150
P +V+L N+ L +V EY+ ++ ++L + + Q
Sbjct: 369 YEHPNVVRL-LDVSHNTITDREIRLNLVFEYIEH-DLATYLAKCPSPGLGPDRIKDLMLQ 542
Query: 151 IVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAK--RVKGRTWTLCGTPEYLAP 208
++ ++LHS +++RDLKP+NLLI + G +++ DFG A+ T+ T Y +P
Sbjct: 543 LLNGVDFLHSNRIVHRDLKPQNLLISKDGRLKLADFGLARIYSFHMALTTVVVTLWYRSP 722
Query: 209 EIILSKGYNKAVDWWALGVLIYEM 232
E+++ Y +VD W+ G + E+
Sbjct: 723 EVLMQAEYGTSVDIWSCGCIFAEL 794
>19301
Length = 712
Score = 60.8 bits (146), Expect = 7e-10, Method: Compositional matrix adjust.
Identities = 46/172 (26%), Positives = 80/172 (46%), Gaps = 3/172 (1%)
Frame = +2
Query: 19 FLAKAKEDFLKK---WESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKIL 75
+ KA LK+ WE P ++ L+ LG+G+ G V L K
Sbjct: 245 IIGKAAAAELKQQDDWEIPFESITDLEW------LGSGAQGAVFLGK----------LCA 376
Query: 76 DKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRR 135
++ V K++ I+ T + R L+ +N P ++ + ++MEY P G+++ LR
Sbjct: 377 EEVAVKKVRDIKET--DIRNLRKLNHPNIISFKGVCTQAPCYCIIMEYCPYGQLYEVLRD 550
Query: 136 IGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFG 187
++ QI YLHS +I+RDLK N+L+ + ++++DFG
Sbjct: 551 GKEIPPALVLDWSKQIASGMNYLHSHKIIHRDLKSPNVLVAKNDVVKISDFG 706
>01966
Length = 1735
Score = 60.8 bits (146), Expect = 8e-10, Method: Compositional matrix adjust.
Identities = 52/188 (27%), Positives = 84/188 (44%), Gaps = 20/188 (10%)
Frame = -1
Query: 61 VKHKETGNHYAMKILDKQKVVKLKQIE-----HTLNEKRILQAVNFPFLVKLEFSFKDNS 115
+H+ TG AMK ++L+ E + E +L+ + +V LE ++
Sbjct: 1654 CRHRATGRKLAMK------KIRLRGSEDGVPSSAIREIAMLRELRHTNIVCLEDVIMEDE 1493
Query: 116 NLYMVMEYV-----------PGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLI 164
L++V E++ P G + RR+ + Y QIV + H ++
Sbjct: 1492 RLFLVFEFLSMDLKMYIDKFPEGVVLD--RRL-------VKSYVFQIVTGINFCHQRRIV 1340
Query: 165 YRDLKPENLLIDQQGYIQVTDFGFAKR----VKGRTWTLCGTPEYLAPEIILSKGYNKAV 220
+RDLKP+NLLI+ G I++ DFG A+ V+ T + T Y APEI++ G
Sbjct: 1339 HRDLKPQNLLINHTGAIKIADFGMARTFALPVRAYTHEVV-TLWYRAPEILM--GPQSTP 1169
Query: 221 DWWALGVL 228
W G L
Sbjct: 1168 PXWTCGAL 1145
>21808
Length = 1011
Score = 58.9 bits (141), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 44/192 (22%), Positives = 85/192 (44%), Gaps = 11/192 (5%)
Frame = +1
Query: 90 LNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSE-PHARFYA 148
L E +I++ + P L++L + ++++ E + G + L+ GR + P
Sbjct: 76 LAEAQIMKKLRHPKLIQLYAVCTQDDPIFIITELMKNGSLLEFLQGKGRVLKLPALIDIG 255
Query: 149 AQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVK--------GRTWTLC 200
AQI YL S + I+RDL N+L+ +++ DFG A+ +K G + +
Sbjct: 256 AQIACGMAYLESQNYIHRDLAARNILVSDNNTVKIADFGLARVIKEDEYEARVGARFPI- 432
Query: 201 GTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAA-GYPPFFADQPIQIYEKIVSG-KVRF 258
++ APE + D W+ G+L+ E G P+ ++ ++ G ++
Sbjct: 433 ---KWTAPEAANYNRFTIKSDVWSFGILLTETVTYGRVPYPGMTNAEVLHQVEHGYRMPC 603
Query: 259 PSHFSSDLKDLL 270
P L D++
Sbjct: 604 PPGCPKPLYDIM 639
>04852
Length = 1462
Score = 58.5 bits (140), Expect = 4e-09, Method: Compositional matrix adjust.
Identities = 41/144 (28%), Positives = 69/144 (47%), Gaps = 8/144 (5%)
Frame = +1
Query: 124 VPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQV 183
PGG + +RR S YA QI E+L S I+RDL N+L+ ++ +++
Sbjct: 298 TPGGHV---IRRKNLLS------YAFQIARGMEFLASRKCIHRDLAARNVLVTEEHVLKI 450
Query: 184 TDFGFA-------KRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEM-AAG 235
DFG + KR GR +++APE + Y D W+ GV+++E+ + G
Sbjct: 451 ADFGLSRTGDYYKKRSGGRL-----PVKWMAPEALFDMRYTTKSDVWSFGVVLWEIFSLG 615
Query: 236 YPPFFADQPIQIYEKIVSGKVRFP 259
P+ + ++Y K++ R P
Sbjct: 616 GMPYASIPNEELYSKLLDDAYRMP 687
>04591
Length = 1117
Score = 56.6 bits (135), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 45/175 (25%), Positives = 86/175 (49%), Gaps = 9/175 (5%)
Frame = -2
Query: 72 MKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVP--GGEM 129
++ L+ + VV+L++I HT QA + + S Y++ EY +
Sbjct: 1059 LQQLEHENVVQLQEICHT-------QAGPY---------NRYKSTFYLIFEYCDYDLAGL 928
Query: 130 FSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGF- 188
++LR +FS + +Q++ Y+H+ +++RD+K N+L+ + G +++ DFG
Sbjct: 927 LNNLRV--KFSLADKKNLMSQLLNGLFYIHTKQILHRDIKAANILLTRDGVLKLADFGLS 754
Query: 189 -----AKRVKGRTWTLCGTPEYLAPEIILS-KGYNKAVDWWALGVLIYEMAAGYP 237
+KR+ R TL Y PE++L + Y +D W +G ++ EM + P
Sbjct: 753 RPWVKSKRLTNRVVTLW----YRPPELLLGEREYGPEIDMWGVGCIMAEMWSRKP 601
>32957
Length = 645
Score = 56.2 bits (134), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 24/41 (58%), Positives = 30/41 (73%)
Frame = +3
Query: 194 GRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAA 234
GRT T CGT EY+APE+ K Y K VDWW LG+L++E+ A
Sbjct: 30 GRTRTFCGTREYMAPEVHERKEYGKEVDWWGLGILLHELLA 152
>12786
Length = 460
Score = 54.7 bits (130), Expect = 5e-08, Method: Compositional matrix adjust.
Identities = 34/120 (28%), Positives = 58/120 (48%), Gaps = 25/120 (20%)
Frame = -3
Query: 145 RFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRV-KGRTWTL---- 199
+FY +++ + LH+ +I+ DLKP N ++ G +++ DFG A + + +T L
Sbjct: 401 KFYWREMLRAVKALHNEGVIHSDLKPANFML-VAGNLKLIDFGIANTLQQDKTSVLKDSR 225
Query: 200 CGTPEYLAPEIILSKGYNKA--------------------VDWWALGVLIYEMAAGYPPF 239
GTP Y++PE I++ + A D W+LG ++Y M G PF
Sbjct: 224 VGTPSYMSPEAIMAACDDSADDSMEEDGHRTKPKYKVGVRSDVWSLGCILYNMVYGRTPF 45
>07940
Length = 1336
Score = 54.7 bits (130), Expect = 5e-08, Method: Compositional matrix adjust.
Identities = 29/91 (31%), Positives = 50/91 (54%), Gaps = 5/91 (5%)
Frame = -3
Query: 147 YAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKG----RTWTLCGT 202
YA Q+ EYL S I+RDL N+L+ ++ +++ DFG + ++ R T
Sbjct: 332 YAYQVARGMEYLASKQCIHRDLAARNVLVAEEYVLKIADFGLTRNLQQFDYYRKTTDGRL 153
Query: 203 P-EYLAPEIILSKGYNKAVDWWALGVLIYEM 232
P +++APE + + Y D W+ GVL++E+
Sbjct: 152 PVKWMAPEALFDRKYTSKSDVWSYGVLLWEI 60
>04138
Length = 800
Score = 53.5 bits (127), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 29/88 (32%), Positives = 47/88 (53%), Gaps = 7/88 (7%)
Frame = +1
Query: 157 YLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAK------RVKGRTWTLCGTPEYLAPEI 210
Y+H +++RD+K N+LI +QG +++ DFG A+ R R T Y PE+
Sbjct: 58 YIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRPPEL 237
Query: 211 ILS-KGYNKAVDWWALGVLIYEMAAGYP 237
+L + Y+ A+D W G ++ EM P
Sbjct: 238 LLGDRNYSTAIDQWGAGCIMAEMWTRNP 321
>11780
Length = 1713
Score = 53.5 bits (127), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 39/145 (26%), Positives = 66/145 (45%), Gaps = 2/145 (1%)
Frame = +3
Query: 48 KTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKL 107
+ +G G FG V G + + KQ K + + L E ++ ++ LV+L
Sbjct: 615 EAIGKGDFGDVY------KGMYRGQPVAIKQLKDKDRGEQSFLQEASVMTSLRHDNLVRL 776
Query: 108 EFSFKDNSNLYMVMEYVPGGEMFSHLRRIGR--FSEPHARFYAAQIVLTFEYLHSLDLIY 165
+++V E++ G + +LR GR ++ +A EYL S L++
Sbjct: 777 -IGVVLGETIFLVTEFMGKGNLVEYLRSRGRSVITKKDQINFATDTCAAMEYLESKRLVH 953
Query: 166 RDLKPENLLIDQQGYIQVTDFGFAK 190
RDL N+L+ G +V+DFG AK
Sbjct: 954 RDLAARNVLVHDDGKAKVSDFGLAK 1028
>16708
Length = 1397
Score = 52.0 bits (123), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 41/161 (25%), Positives = 70/161 (43%), Gaps = 14/161 (8%)
Frame = -1
Query: 47 IKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQ---IEHTLNEKRILQAVNFPF 103
++ LG G FG+V Y ++L + LK H+L+E L + F
Sbjct: 1388 LQVLGKGVFGKV-----------YEARLLSTHEKAALKTSILCHHSLDEVEALGRIEGGF 1242
Query: 104 LVKLEFS-------FKDNSNLYMVMEYVPGGEMFSHLRRIG---RFSEPH-ARFYAAQIV 152
+ F F + L E P +++H + R+S P A Q V
Sbjct: 1241 YLAQMFGAWVTCLPFPKMNILLHFYEMGPLCNVYAHYKNKEMPIRWSNPAMVCCIAGQXV 1062
Query: 153 LTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVK 193
E++H L +++ D+K +N+L+D G ++TD+G A+ K
Sbjct: 1061 CALEHIHELGVVHMDVKADNVLVDAHGNCKLTDYGIAQLYK 939
>03508
Length = 1463
Score = 52.0 bits (123), Expect = 4e-07, Method: Compositional matrix adjust.
Identities = 30/113 (26%), Positives = 62/113 (54%), Gaps = 4/113 (3%)
Frame = +1
Query: 139 FSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQG-YIQVTDFGFAKRVK-GRT 196
F++ RFY +++ ++ HS+ +++RD+KP N++ID + +++ D+G A+ G
Sbjct: 862 FTDYDIRFYLYELMKALDFCHSMGIMHRDVKPHNVMIDHENKKLRLIDWGLAEFYHPGME 1041
Query: 197 WTLCGTPEYL-APEIILS-KGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQI 247
+ + Y PE++L + Y+ ++D W+LG + M P +P Q+
Sbjct: 1042YNVRVASRYFKGPELLLDYQMYDYSLDMWSLGCMFASMIFRKEPLLP-RPRQL 1197
>20152
Length = 445
Score = 50.8 bits (120), Expect = 8e-07, Method: Compositional matrix adjust.
Identities = 29/96 (30%), Positives = 44/96 (45%), Gaps = 1/96 (1%)
Frame = +1
Query: 208 PEIILSKGYN-KAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDL 266
PEI+L Y+ AVD W+LGV++Y + G PF + I+ + + P H S
Sbjct: 1 PEILLGDSYDAPAVDVWSLGVILYMLVVGEAPFQEANDSETLTMIMDCRYQIPPHISHKC 180
Query: 267 KDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTD 302
+DL+ +LQ + R + I H W D
Sbjct: 181 QDLIEKMLQREPVDR-----ASLPHILAHPWLNDGD 273
>37602
Length = 804
Score = 50.4 bits (119), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 26/90 (28%), Positives = 43/90 (47%)
Frame = -1
Query: 97 QAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFE 156
+ VN V S+ L++ MEY GG M G +EP F + +
Sbjct: 354 RIVNIQTFVGYFDSYLRREKLWIAMEYCGGGSMQDIYHVTGPLTEPQIAFVCRETLKGLH 175
Query: 157 YLHSLDLIYRDLKPENLLIDQQGYIQVTDF 186
YLH ++RD+K N+L+ ++G +++ DF
Sbjct: 174 YLHRRGKMHRDIKGANILLTEEGDVKLADF 85
>00715
Length = 1788
Score = 50.1 bits (118), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 52/226 (23%), Positives = 97/226 (42%), Gaps = 29/226 (12%)
Frame = +1
Query: 61 VKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMV 120
+ HK + N A++ +++ + +N IL A + F+D + ++
Sbjct: 19 IYHKRSSNPRALRQSYSNELLAFRCGLRHVNVVSILGATSL-------HRFEDGA--WLA 171
Query: 121 MEYVPGGEMFSHLRRIGRFSEPHARF-YAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQG 179
MEYV + + L + + R A Q+ YLHS+++++ DLKP N L+ +
Sbjct: 172 MEYVGPLNLQTILNDHQQDIDSSMRLSLALQMARGLHYLHSINIVHLDLKPANCLLTRDL 351
Query: 180 YIQVTDFGFAKR------------------------VKGRTWT--LCGTPEYLAPEIILS 213
+++ DFG + V+G W L GT Y APE++
Sbjct: 352 KLRIADFGCCHQLTPTGLDMGEREGGMAGNELELTPVQG-AWKNELAGTLAYRAPELL-- 522
Query: 214 KGYNKAV--DWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVR 257
KG +V D ++LG+ +++M P+ + ++VS +R
Sbjct: 523 KGLQPSVRSDVYSLGITLWQMCTRQGPYEGVPAHAVVYQVVSKDLR 660
>14116
Length = 1017
Score = 47.8 bits (112), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 27/123 (21%), Positives = 61/123 (49%), Gaps = 9/123 (7%)
Frame = -1
Query: 119 MVMEYVPGGEMFSHLRRIGRFSEPHAR---FYAAQIVLTFEYLHSLDLIYRDLKPENLLI 175
+V+ ++ G++ +++R +P + Y I +YL L ++RDL N ++
Sbjct: 393 VVLPFMKHGDLLTYIR--DDQHQPTIKDLIMYGVDIARGMDYLAGLKFVHRDLAARNCML 220
Query: 176 DQQGYIQVTDFGFAKRVKGRTWTLCGTP------EYLAPEIILSKGYNKAVDWWALGVLI 229
D+ +++V DFG A+ + + + +++A E + Y+ D W+ GV++
Sbjct: 219 DEDFHVKVADFGLARDIYEKEYYSSENKKAKLPVKWMALESLEKGNYDSKTDVWSYGVVL 40
Query: 230 YEM 232
+E+
Sbjct: 39 WEL 31
>27274
Length = 396
Score = 46.6 bits (109), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 28/102 (27%), Positives = 49/102 (48%), Gaps = 11/102 (10%)
Frame = -1
Query: 209 EIILSKGYNKAVDWWALGVLIYEMAAGYPPF--------FADQPIQIYEKIVSGKVRFPS 260
E++ + + VD W+LG+L++E+ +G+ PF A + +Y +I+ G R
Sbjct: 375 ELLRGQQHGPTVDMWSLGILLHELLSGHVPFEPERGSRQMARNMMAVYAQIIRGSSRDVC 196
Query: 261 H---FSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFA 299
S+ D LR L+Q++ TKR + +H W A
Sbjct: 195 DGLALSTHGADFLRRLVQLEDTKRLTS-----QQAFSHPWIA 85
>07291
Length = 833
Score = 45.8 bits (107), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 25/100 (25%), Positives = 54/100 (54%), Gaps = 7/100 (7%)
Frame = +1
Query: 147 YAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTW-TLCGTP-- 203
+ QI YL + +++R+L N ++ + G +Q++D+G + +++ T +P
Sbjct: 64 FGRQIADGMAYLQEVKVVHRNLAARNCIVTEDGRLQLSDYGVTGSLFPQSYYTADDSPAR 243
Query: 204 ---EYLAPEIILSKGYNKAVDWWALGVLIYEMAA-GYPPF 239
+++APE I + ++ D WA GV+++E+ G P+
Sbjct: 244 DLVKWMAPETIDNFHFSSKSDVWAFGVVLWELLTRGITPY 363
>17300
Length = 480
Score = 45.8 bits (107), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 41/152 (26%), Positives = 71/152 (46%), Gaps = 14/152 (9%)
Frame = +1
Query: 158 LHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRT----WTLCGTP---EYLAPEI 210
L + ++RDL N+L+++ +V DFG ++ ++ T +T G + APE
Sbjct: 22 LADMGYVHRDLAARNILVNEILVCKVADFGLSREIESDTTEGAYTTKGGKIPVRWTAPEA 201
Query: 211 ILSKGYNKAVDWWALGVLIYE-MAAGYPPFFADQPIQIYEKIVSGKVRFPSH------FS 263
I + + A D W+ GV+++E M+ G P++ + Q K V R P H S
Sbjct: 202 IAYRKFTSASDVWSFGVVMWEVMSYGERPYW-NWSNQDVIKAVEKGYRLPLHGLSGSPSS 378
Query: 264 SDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNH 295
+D + L ++ TK N+ G N + H
Sbjct: 379 TDARRLAEG--EISQTK---NVHGG*NTRQTH 459
>02638
Length = 1490
Score = 44.7 bits (104), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 27/106 (25%), Positives = 49/106 (46%), Gaps = 5/106 (4%)
Frame = +1
Query: 199 LCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFA---DQPIQIYEKIVSG- 254
L GT ++APE++ + Y +A D W++G ++ EM PP+ + + + KI S
Sbjct: 16 LLGTIAFMAPEVLRGESYGRACDVWSVGCVMIEMCTCRPPWNSHDISNHLALIFKIASSV 195
Query: 255 -KVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFA 299
P + S ++DL+ L+ D + + D+ H F
Sbjct: 196 DPPPIPENMSPPVRDLMLRCLEQD-----SDFRPSAKDLLMHPLFT 318
>17932
Length = 597
Score = 44.3 bits (103), Expect = 8e-05, Method: Compositional matrix adjust.
Identities = 30/100 (30%), Positives = 46/100 (46%)
Frame = -3
Query: 243 QPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTD 302
QPI I I +V S S + +DL+ LL G + G +++ H +F T D
Sbjct: 517 QPITIS*TIRQTQVPPHSSVSKEARDLISQLLSD------GKSRLGWPELQQHPFFKTVD 356
Query: 303 WIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINE 342
W I R P++P DTS+FD+ E+ +I+
Sbjct: 355 WANI--RNAMPPYVPSISSLDDTSHFDEVEKARPAPNIDS 242
Score = 32.3 bits (72), Expect = 0.28, Method: Compositional matrix adjust.
Identities = 16/41 (39%), Positives = 20/41 (48%), Gaps = 2/41 (4%)
Frame = -2
Query: 222 WWALGVLIYEMAAGYPPFFADQP--IQIYEKIVSGKVRFPS 260
WW+LGV YEM G PF D + Y I++ K S
Sbjct: 596 WWSLGVCAYEMLFGCTPFTDDDGSMVATYNNIMNYKTNSSS 474
>33586
Length = 551
Score = 43.5 bits (101), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 16/49 (32%), Positives = 33/49 (67%)
Frame = +2
Query: 103 FLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQI 151
F+V L ++F+ LY+++E++ GG++F+ L + F+E +FY A++
Sbjct: 404 FIVHLHYAFQTEGKLYLILEFLRGGDLFTRLSKEVMFTEEDVKFYLAEL 550
Score = 29.3 bits (64), Expect = 2.5, Method: Compositional matrix adjust.
Identities = 13/20 (65%), Positives = 14/20 (70%)
Frame = +1
Query: 39 AHLDQFERIKTLGTGSFGRV 58
A QFE +K LG GSFGRV
Sbjct: 205 ADPSQFELLKVLGQGSFGRV 264
>18401
Length = 463
Score = 42.7 bits (99), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 16/42 (38%), Positives = 26/42 (61%)
Frame = -3
Query: 198 TLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPF 239
T+ T Y APE+IL G++ D W++G +++E+ GY F
Sbjct: 455 TIVSTRHYRAPEVILELGWSHPCDVWSVGCIMFELYTGYTLF 330
>12672
Length = 773
Score = 41.2 bits (95), Expect = 7e-04, Method: Compositional matrix adjust.
Identities = 28/88 (31%), Positives = 46/88 (52%), Gaps = 7/88 (7%)
Frame = +3
Query: 155 FEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGF---AKRVKGRTW----TLCGTPEYLA 207
+YL+ ++RD+K N+L+D + +V DF A +G+T + GT YLA
Sbjct: 30 IQYLNDNGHVHRDIKTANILLDSEYTAKVGDFATVVSAPSGEGKTVQNASVVIGTAAYLA 209
Query: 208 PEIILSKGYNKAVDWWALGVLIYEMAAG 235
PE I K +D ++ GV++ E+ G
Sbjct: 210 PEAIHFDVSTK-LDSYSFGVVLLEVITG 290
>31489
Length = 329
Score = 40.8 bits (94), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 24/69 (34%), Positives = 40/69 (57%), Gaps = 4/69 (5%)
Frame = +3
Query: 110 SFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEP----HARFYAAQIVLTFEYLHSLDLIY 165
S+ D ++++V + M S L RI +P H R++ QI+ +Y+HS ++++
Sbjct: 72 SYHDFKDIHVVFDL-----MESDLHRIIYSDQPLTEEHIRYFLYQILRGLKYIHSANVVH 236
Query: 166 RDLKPENLL 174
RDLKP NLL
Sbjct: 237 RDLKPSNLL 263
>29590
Length = 320
Score = 40.4 bits (93), Expect = 0.001, Method: Composition-based stats.
Identities = 17/41 (41%), Positives = 25/41 (60%)
Frame = +3
Query: 199 LCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPF 239
+ GTP+Y+APE++ + + D W+LGVL Y M PF
Sbjct: 54 IIGTPDYVAPEVLDYEPLSIQTDMWSLGVLSYVMLTACSPF 176
>26009
Length = 886
Score = 40.0 bits (92), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 23/72 (31%), Positives = 35/72 (48%), Gaps = 3/72 (4%)
Frame = +3
Query: 127 GEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQV--- 183
G + RR A+ Q+V +++HS L++RD+KPEN+LI + +V
Sbjct: 666 GTCLTPSRRNKACGSREAKSVMKQLVSALDFMHSKQLVHRDIKPENVLILTPDFSRVS*W 845
Query: 184 TDFGFAKRVKGR 195
T A RV R
Sbjct: 846 TSA*LANRVHRR 881
>11404
Length = 563
Score = 40.0 bits (92), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 43/149 (28%), Positives = 72/149 (48%), Gaps = 6/149 (4%)
Frame = +1
Query: 33 SPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKIL-DKQKVVKLKQIEHTLN 91
SP + A D++E +G GSFG+V+ A+KI+ +K+ + QIE L
Sbjct: 118 SPGEKWA--DRYEIDSLIGKGSFGQVVKAYDHTDNEQVAIKIIKNKKPFLNQAQIEVKLL 291
Query: 92 EKRILQAV-NFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIG--RFSEPHARFYA 148
E N ++V+L+ F S+L +V E + ++ LR S R +A
Sbjct: 292 EMMNRHDTDNKYYIVRLKRHFMFRSHLCLVFELLSYN-LYDLLRNTNFRGVSLNLTRKFA 468
Query: 149 AQIVLTFEYLHS--LDLIYRDLKPENLLI 175
Q+ +L + + +I+ DLKPEN+L+
Sbjct: 469 QQLCTALLFLATPEMSIIHCDLKPENILL 555
>14477
Length = 493
Score = 40.0 bits (92), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 34/152 (22%), Positives = 71/152 (46%), Gaps = 2/152 (1%)
Frame = -1
Query: 43 QFERIKTLGTGSFGRVM--LVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVN 100
Q + +K LG G+FG VM + + + A+K+L + Q E + E +++ ++
Sbjct: 484 QMDELK-LGAGNFGSVMKGVCRLDDREIPVAIKVLKNADLDPSVQSE-LIKEAEVMKKMD 311
Query: 101 FPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHS 160
+V+L + + +V+E G + L + + Q+ EYL +
Sbjct: 310 HMHIVRL-IGLCEGETMMLVLELAKLGPLNKFLPKNKHLPLWNILELMWQVSQGMEYLEA 134
Query: 161 LDLIYRDLKPENLLIDQQGYIQVTDFGFAKRV 192
++RDL N+L+ + + +++DFG +K +
Sbjct: 133 NKFVHRDLAARNILLCDEHFAKISDFGMSKTL 38
>37063
Length = 455
Score = 38.5 bits (88), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 24/78 (30%), Positives = 40/78 (51%), Gaps = 16/78 (20%)
Frame = -2
Query: 168 LKPENLL---IDQQGYIQVTDFGFAKRVKG--------RTWTLCGTPEYLAPEII----- 211
LKPEN+L +D+ +++ DF A + T G+ EY+APE++
Sbjct: 454 LKPENILCEHLDEVVPLKICDFDLASGINCDGDGTKTPELLTPVGSAEYMAPEVVDAWVG 275
Query: 212 LSKGYNKAVDWWALGVLI 229
S Y+K D W+LG+++
Sbjct: 274 ESFSYDKRCDMWSLGIIL 221
>17516
Length = 453
Score = 38.1 bits (87), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 17/39 (43%), Positives = 28/39 (71%), Gaps = 1/39 (2%)
Frame = -3
Query: 198 TLCGTPEYLAPEIILSKG-YNKAVDWWALGVLIYEMAAG 235
TL GTP Y+APE++L KG Y+ D ++L ++++E+ G
Sbjct: 442 TLAGTPVYMAPEVLLQKGQYDMKADVYSLAIILWELWYG 326
>20640
Length = 1492
Score = 38.1 bits (87), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 25/86 (29%), Positives = 42/86 (48%), Gaps = 5/86 (5%)
Frame = +1
Query: 164 IYRDLKPENLLIDQQGYIQVTDFGFAKRVKG----RTWTLCGTP-EYLAPEIILSKGYNK 218
++RDL N L+ ++++DFG A+ V R P ++ E IL ++
Sbjct: 10 VHRDLATRNCLVGHDLVVKISDFGLARSVHSVDYYRGSEHDAIPIRWMPLEAILYNKFST 189
Query: 219 AVDWWALGVLIYEMAAGYPPFFADQP 244
D W+ GV+++E+ A FA QP
Sbjct: 190 QSDVWSFGVVLWEIFA-----FALQP 252
>18481
Length = 437
Score = 37.4 bits (85), Expect = 0.008, Method: Compositional matrix adjust.
Identities = 23/75 (30%), Positives = 38/75 (50%), Gaps = 3/75 (4%)
Frame = -1
Query: 128 EMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQ---VT 184
E+F +R RF+ + Q++ E++H I+RDLKP+N L+ + +
Sbjct: 233 ELFVICKR--RFTLKTILMVSDQLLSRLEFIHQKCFIHRDLKPDNFLMGLGRHCHRLYII 60
Query: 185 DFGFAKRVKGRTWTL 199
DFG +KR K T+
Sbjct: 59 DFGLSKRYKDTQGTM 15
>18996
Length = 491
Score = 37.4 bits (85), Expect = 0.010, Method: Compositional matrix adjust.
Identities = 21/74 (28%), Positives = 41/74 (55%), Gaps = 5/74 (6%)
Frame = +2
Query: 164 IYRDLKPENLLIDQQGYIQVTDFGFAK--RVKGRTWTLCGTP---EYLAPEIILSKGYNK 218
I+RDL N+L+D+ ++++DFG A+ G + + ++ +PE I + ++
Sbjct: 2 IHRDLAARNILVDR-SCVKISDFGLAQFANADGYYYGISQRDIPIKWYSPEAIETCKFSS 178
Query: 219 AVDWWALGVLIYEM 232
D W+ GV ++EM
Sbjct: 179 YSDVWSYGVTLFEM 220
>17637
Length = 447
Score = 37.0 bits (84), Expect = 0.011, Method: Compositional matrix adjust.
Identities = 24/89 (26%), Positives = 42/89 (47%), Gaps = 6/89 (6%)
Frame = +1
Query: 172 NLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEY-----LAPEIILSKGYNKAVDWWALG 226
N +ID Q +++TD ++ + + G EY L+ E + YN+ D W+ G
Sbjct: 1 NCVIDDQLRVKLTDSALSRDLFSGDYNCLGDGEYRPIKWLSLEALQKSHYNEGSDVWSFG 180
Query: 227 VLIYEMAA-GYPPFFADQPIQIYEKIVSG 254
VL++EM G P+ P ++ + G
Sbjct: 181 VLMWEMCTLGKLPYAEIDPYEMEHYLKDG 267
>17253
Length = 483
Score = 37.0 bits (84), Expect = 0.012, Method: Compositional matrix adjust.
Identities = 20/86 (23%), Positives = 44/86 (51%), Gaps = 12/86 (13%)
Frame = -1
Query: 119 MVMEYVPGGEMFSHLRR---------IGRFSEPHAR---FYAAQIVLTFEYLHSLDLIYR 166
++ME+ G++ S LR+ ++ AR +A + ++ + +++R
Sbjct: 315 ILMEFCCHGDLLSFLRKRRPDRTVFLTSTANDLTARDFFSFALHVARGMAHVANNKIVHR 136
Query: 167 DLKPENLLIDQQGYIQVTDFGFAKRV 192
D+ N+LI ++ +V+DFG ++RV
Sbjct: 135 DVAARNVLISERNVCKVSDFGLSRRV 58
>21800
Length = 855
Score = 36.6 bits (83), Expect = 0.014, Method: Compositional matrix adjust.
Identities = 35/148 (23%), Positives = 61/148 (41%), Gaps = 3/148 (2%)
Frame = +2
Query: 31 WESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTL 90
W P + A L L V + E+ HY LD+ K++K +
Sbjct: 305 WTVPCRQKAGLGSLLHCLALLGSQL*AVCRFEGCESAQHYTETALDEIKLLKCVRNSDET 484
Query: 91 NEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEP--HARFYA 148
+ R + L + S + +++ MV E V G + + R P + +
Sbjct: 485 DPAR---EKSVQLLDDFKISGVNGTHVCMVFE-VLGYNLLKLIIRSNYQGIPVHNVKLII 652
Query: 149 AQIVLTFEYLHS-LDLIYRDLKPENLLI 175
Q++ YLH+ ++I+ D+KPEN+LI
Sbjct: 653 RQVLEGLNYLHAKCNIIHTDIKPENILI 736
>01106
Length = 878
Score = 36.6 bits (83), Expect = 0.017, Method: Compositional matrix adjust.
Identities = 40/166 (24%), Positives = 71/166 (42%), Gaps = 15/166 (9%)
Frame = +3
Query: 25 EDFLKKWESPAQNTAHLD-QFERIKTLGTGSFGRVML-----------VKHKETGNHYAM 72
D+ K P +N + ++ I+ LG G F V L +K ++ HY
Sbjct: 264 RDYCKGGYHPVKNGDLFNGRYHVIRKLGWGHFSTVWLCWDLTCKRFVALKVVKSAQHYTE 443
Query: 73 KILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSH 132
LD+ K++K + + R A L + S + +++ MV E V G +
Sbjct: 444 TALDEVKLLKCVRESDVADPAR---AKCVQLLDDFKISGVNGTHVAMVFE-VLGYNLLKL 611
Query: 133 LRRIGRFSEP--HARFYAAQIVLTFEYLHS-LDLIYRDLKPENLLI 175
+ R P + + Q++ Y+H+ +I+ D+KPEN+LI
Sbjct: 612 IIRSNYQGIPIHNVKLIIRQVLEGLSYMHAKCRIIHTDIKPENILI 749
>06358
Length = 1517
Score = 36.2 bits (82), Expect = 0.021, Method: Compositional matrix adjust.
Identities = 32/154 (20%), Positives = 68/154 (44%), Gaps = 22/154 (14%)
Frame = +3
Query: 150 QIVLTFEYLHS-LDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTP----- 203
Q+ +LH+ +++R++ PE +++ + G ++ + F R T P
Sbjct: 384 QVTEALGFLHNDAKMMHRNVCPEAIMLTKLGSWKLAGYEFCVRSSDPQSTDPSYPFYEWR 563
Query: 204 -----------EYLAPEIILSKGYNKAVDWWALGVLIYEM-AAGYPPFFADQPIQIY--- 248
+++APE +L+ D ++LG+L+Y + A G P F + + +
Sbjct: 564 SDIAPVTQPHLDFMAPEYVLTMQCGTGSDMFSLGLLVYSVFAKGKPLFECNGELSAFKSN 743
Query: 249 -EKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKR 281
E++ +V DL+D ++ LL ++ R
Sbjct: 744 AEELRHMRVSLLGVVPEDLRDHVKLLLNIEPAVR 845
>26052
Length = 562
Score = 35.8 bits (81), Expect = 0.024, Method: Compositional matrix adjust.
Identities = 16/31 (51%), Positives = 22/31 (70%)
Frame = -1
Query: 43 QFERIKTLGTGSFGRVMLVKHKETGNHYAMK 73
Q+ K LG GSFG+VM ++HK+TG A+K
Sbjct: 388 QYLFXKLLGVGSFGKVMALQHKDTGETLAVK 296
>36481
Length = 806
Score = 35.8 bits (81), Expect = 0.029, Method: Compositional matrix adjust.
Identities = 33/132 (25%), Positives = 60/132 (45%), Gaps = 4/132 (3%)
Frame = +2
Query: 51 GTGSFGRVMLVKHKETGNHYAMKIL-DKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEF 109
G G+FG+V+ K G+ A+KI+ + K + ++E + EK + + +
Sbjct: 389 GEGTFGKVVQCKDLLKGDDIALKIIKNVDKYREAAKLEINVLEKLREKDPHAKHMCVQML 568
Query: 110 SFKDNSNLYMVMEYVPGGEMFSHLR--RIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRD 167
+ D + ++ G +F L+ G + R + Q+ +LH L + D
Sbjct: 569 DWFDYHGHVCISFHMLGLSVFDFLKDNSYGAYPIEQVRHISYQLCYAVNFLHENQLTHTD 748
Query: 168 LKPENLL-IDQQ 178
LKPEN+L +D Q
Sbjct: 749 LKPENILFVDSQ 784
>25360
Length = 751
Score = 35.0 bits (79), Expect = 0.040, Method: Compositional matrix adjust.
Identities = 21/54 (38%), Positives = 28/54 (51%), Gaps = 5/54 (9%)
Frame = -3
Query: 166 RDLKPENLLIDQQGYI-QVTDFGFAKRVKGRTWT--LCGTPEYL--APEIILSK 214
R L P L QG +V D G+A V G+TWT +CGTP + P + S+
Sbjct: 422 RSLTPGGLEALFQGQCPRVQDLGWASHVNGKTWTHYVCGTPHWQHDCPRRVRSR 261
>11089
Length = 1213
Score = 34.7 bits (78), Expect = 0.054, Method: Compositional matrix adjust.
Identities = 21/54 (38%), Positives = 28/54 (51%), Gaps = 5/54 (9%)
Frame = +2
Query: 166 RDLKPENLLIDQQGYI-QVTDFGFAKRVKGRTWT--LCGTPEYL--APEIILSK 214
R L P L QG +V D G+A V G+TWT +CGTP + P + S+
Sbjct: 974 RSLTPGGLEALFQGQCPRVQDLGWASHVNGKTWTHYVCGTPHWQHDCPRRVRSR 1135
>21210
Length = 518
Score = 34.3 bits (77), Expect = 0.068, Method: Compositional matrix adjust.
Identities = 27/91 (29%), Positives = 43/91 (47%), Gaps = 10/91 (10%)
Frame = +3
Query: 201 GTPEYLAPEII----LSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIY---EKIVS 253
G Y+APE I S GY+ D W+LG+ + E+A G P+ + + I+ +++V
Sbjct: 6 GCRPYMAPERIDPRASSHGYDVRSDVWSLGITLMELATGRFPY--RKWVSIFDQLQQVVR 179
Query: 254 GKVRFPSH---FSSDLKDLLRNLLQVDLTKR 281
G H FS D + + L D +R
Sbjct: 180 GVAPCLPHDGAFSHDFVNFVNKCLTKDEKQR 272
>28865
Length = 342
Score = 33.5 bits (75), Expect = 0.14, Method: Compositional matrix adjust.
Identities = 19/60 (31%), Positives = 29/60 (48%), Gaps = 3/60 (5%)
Frame = -3
Query: 21 AKAKEDFLKKWESPAQNTAHLDQFERI---KTLGTGSFGRVMLVKHKETGNHYAMKILDK 77
AK E+ ++PA + Q +I LG+G FG V H+ T A+K++DK
Sbjct: 274 AKDNENVTANEDTPADKQVDISQLYQIFPEDVLGSGQFGIVYGGCHRRTNREVAIKVIDK 95
>17591
Length = 474
Score = 32.7 bits (73), Expect = 0.20, Method: Compositional matrix adjust.
Identities = 14/46 (30%), Positives = 28/46 (60%)
Frame = +2
Query: 230 YEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQ 275
+EM G PPF++ ++YE I+ +R ++ S+ +++L LL+
Sbjct: 2 FEMLYGLPPFYSRDTSEMYENILYKPLRLRTNVSAAGRNILEELLK 139
>30339
Length = 384
Score = 32.0 bits (71), Expect = 0.34, Method: Compositional matrix adjust.
Identities = 15/25 (60%), Positives = 17/25 (68%)
Frame = -2
Query: 40 HLDQFERIKTLGTGSFGRVMLVKHK 64
HL F IK LG GSFG+VML + K
Sbjct: 80 HLHDFNFIKVLGKGSFGKVMLAERK 6
>31120
Length = 439
Score = 31.6 bits (70), Expect = 0.52, Method: Compositional matrix adjust.
Identities = 24/95 (25%), Positives = 43/95 (45%), Gaps = 1/95 (1%)
Frame = +1
Query: 209 EIILSKGYN-KAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLK 267
E++ Y+ K D W+LGV+++ M G PF ++ E S K F +
Sbjct: 1 EVVCGVPYDPKMADAWSLGVILFIMLNGKMPFDDSNLNKLLEDQRSKKYSFRRKLQDLVS 180
Query: 268 DLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTD 302
R+ + V L + ++ +N++ N +W T D
Sbjct: 181 PNARSTVSV-LLEPNSAMRWDLNEVLNCQWLQTID 282
>00638
Length = 1595
Score = 30.8 bits (68), Expect = 0.84, Method: Compositional matrix adjust.
Identities = 11/38 (28%), Positives = 25/38 (65%)
Frame = +2
Query: 139 FSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLID 176
F++ RFY +++ ++ HS+ +++RD+KP L++
Sbjct: 407 FTDYDIRFYLYELMKALDFCHSMGIMHRDVKPSPPLVN 520
>16350
Length = 1108
Score = 30.4 bits (67), Expect = 1.3, Method: Compositional matrix adjust.
Identities = 10/34 (29%), Positives = 18/34 (52%)
Frame = +2
Query: 202 TPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAG 235
T +Y E+++ GY D W+ + +E+A G
Sbjct: 419 TRQYRCLEVLIGAGYGTPADIWSTACMAFELATG 520
>32357
Length = 625
Score = 30.0 bits (66), Expect = 1.4, Method: Compositional matrix adjust.
Identities = 19/63 (30%), Positives = 33/63 (52%), Gaps = 1/63 (1%)
Frame = -2
Query: 42 DQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQ-AVN 100
++ +K +G+GSFG + L H +G A+K+ + K K Q+ + R+LQ V
Sbjct: 438 GKYRLMKKIGSGSFGEIYLGVHNTSGEEVAVKL--ELKNAKHPQLYYESKLYRVLQGGVG 265
Query: 101 FPF 103
P+
Sbjct: 264 IPY 256
>06167
Length = 1470
Score = 28.9 bits (63), Expect = 3.1, Method: Compositional matrix adjust.
Identities = 12/42 (28%), Positives = 22/42 (52%)
Frame = -2
Query: 183 VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWA 224
+ D FA R +CG+ + P ++L+ NK+V +W+
Sbjct: 128 IIDESFACRFCM*YCVVCGSKYLILPSVLLNLNINKSVSFWS 3
>36002
Length = 253
Score = 28.9 bits (63), Expect = 3.6, Method: Composition-based stats.
Identities = 18/55 (32%), Positives = 26/55 (47%), Gaps = 4/55 (7%)
Frame = +1
Query: 247 IYEKIVSGKVRFPSH----FSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKW 297
++ +I G FPS SS KDL+R+LL + KR+ D+ H W
Sbjct: 58 LFNRIQDGNYFFPSMEWSAISSSAKDLIRHLLVREPRKRY-----SAADVLKHPW 207
>23319
Length = 2235
Score = 28.5 bits (62), Expect = 4.3, Method: Compositional matrix adjust.
Identities = 10/33 (30%), Positives = 19/33 (57%)
Frame = +3
Query: 208 PEIILSKGYNKAVDWWALGVLIYEMAAGYPPFF 240
P++ +K Y+ ++D W+ G + E+A P F
Sbjct: 3 PDVYXAKMYSTSIDMWSAGCIFAELANAGRPLF 101
>29360
Length = 363
Score = 27.7 bits (60), Expect = 7.9, Method: Compositional matrix adjust.
Identities = 12/33 (36%), Positives = 19/33 (57%)
Frame = +3
Query: 143 HARFYAAQIVLTFEYLHSLDLIYRDLKPENLLI 175
+ R Q++ L L LI+ DLKPEN+++
Sbjct: 261 YIRPITQQVLTALRKLKQLGLIHADLKPENIML 359
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000341189 | hsapiens_gene_ensembl | Focal adhesion
kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK) (Protein- tyrosine kinase
2). [Source:Uniprot/SWISSPROT;Acc:Q05397]
(1052 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
06405 221 2e-57
21808 199 4e-51
11780 121 2e-44
09007 176 6e-44
04852 162 7e-40
14116 147 3e-35
07291 137 2e-32
17300 124 6e-30
20640 125 9e-29
07940 119 9e-27
08294 117 2e-26
18996 111 2e-24
14477 108 1e-23
17253 97 5e-20
22005 96 8e-20
18921 96 9e-20
17637 90 5e-18
13305 87 3e-17
00300 87 4e-17
01718 87 4e-17
19301 83 7e-16
12721 78 2e-14
14420 75 2e-13
13592 73 7e-13
27546 70 6e-12
30755 69 9e-12
00715 68 2e-11
13066 67 4e-11
31885 67 4e-11
07833 66 7e-11
09606 65 1e-10
14126 65 2e-10
01060 63 7e-10
19094 62 1e-09
13212 61 2e-09
29581 60 5e-09
01756 59 9e-09
19761 59 1e-08
04591 59 2e-08
03240 57 4e-08
21079 57 5e-08
01707 56 8e-08
18484 55 1e-07
07836 54 3e-07
01966 54 4e-07
26711 51 3e-06
15910 51 3e-06
12672 49 9e-06
25550 49 1e-05
32264 49 1e-05
21433 48 2e-05
28157 46 6e-05
26560 44 3e-04
04138 44 4e-04
01392 42 0.001
12786 41 0.002
07933 40 0.005
03508 40 0.005
37602 39 0.014
38046 38 0.018
18481 37 0.030
11185 37 0.032
02638 36 0.063
00486 35 0.18
26009 35 0.21
16708 34 0.29
15741 34 0.35
27287 34 0.36
27405 33 0.40
21210 33 0.63
25019 32 1.8
32359 30 3.5
>06405
Length = 1965
Score = 221 bits (562), Expect = 2e-57, Method: Compositional matrix adjust.
Identities = 109/275 (39%), Positives = 165/275 (60%), Gaps = 2/275 (0%)
Frame = +1
Query: 410 PSTRDYEIQRERIELGRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFL 469
P +EI+R I + +G GQ+GDV++ ++ VA+KT K T FL
Sbjct: 229 PEPDRWEIERTEIAMKHRLGGGQYGDVYEAMWKRYNK---IVAVKTLKEDTM--ALNDFL 393
Query: 470 QEALTMRQFDHPHIVKLIGVIT-ENPVWIIMELCTLGELRSFLQVRKYSLDLASLILY-A 527
+EA M++ HP++V+L+GV T E P +I+ E G L +L+ + + ++Y A
Sbjct: 394 EEAAIMKEMKHPNLVQLLGVCTREPPFYIVTEFMPHGNLLDYLRSSTREENGPTALMYMA 573
Query: 528 YQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIK 587
Q+++ +AYLE+K F+HRD+AARN LV+ ++ VK+ DFGL+R M+D TY K PIK
Sbjct: 574 TQIASGMAYLETKNFIHRDLAARNCLVADSNMVKVADFGLARLMKDDTYTAHIGAKFPIK 753
Query: 588 WMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNC 647
W APE + F RF++ SD+W FGV +WE+ +G+ P+ GV+ +V +E G R+ PP
Sbjct: 754 WTAPEGLAFNRFSTRSDIWAFGVLLWELATYGMSPYPGVELTEVYHLLERGYRMERPPGT 933
Query: 648 PPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEE 682
P +Y LM KCW +DP RP F E+ L + E+
Sbjct: 934 PADVYILMLKCWQWDPKDRPTFKEIHFLLENMFEK 1038
>21808
Length = 1011
Score = 199 bits (507), Expect = 4e-51, Method: Compositional matrix adjust.
Identities = 98/236 (41%), Positives = 144/236 (61%), Gaps = 1/236 (0%)
Frame = +1
Query: 446 NPALAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITEN-PVWIIMELCTL 504
N VAIKT K+ T D + FL EA M++ HP +++L V T++ P++II EL
Sbjct: 13 NNTTPVAIKTLKSGTMDP--KDFLAEAQIMKKLRHPKLIQLYAVCTQDDPIFIITELMKN 186
Query: 505 GELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGD 564
G L FLQ + L L +LI Q++ +AYLES+ ++HRD+AARN+LVS N+ VK+ D
Sbjct: 187 GSLLEFLQGKGRVLKLPALIDIGAQIACGMAYLESQNYIHRDLAARNILVSDNNTVKIAD 366
Query: 565 FGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQ 624
FGL+R +++ Y + PIKW APE+ N+ RFT SDVW FG+ + E + +G P+
Sbjct: 367 FGLARVIKEDEYEARVGARFPIKWTAPEAANYNRFTIKSDVWSFGILLTETVTYGRVPYP 546
Query: 625 GVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTIL 680
G+ N +V+ ++E+G R+P PP CP LY +M +CW + RP + IL
Sbjct: 547 GMTNAEVLHQVEHGYRMPCPPGCPKPLYDIMLECWRKEEMERPHLRNPAMEAGGIL 714
>11780
Length = 1713
Score = 121 bits (303), Expect(2) = 2e-44, Method: Compositional matrix adjust.
Identities = 69/179 (38%), Positives = 102/179 (56%), Gaps = 1/179 (0%)
Frame = +3
Query: 417 IQRERIELGRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTMR 476
I + +E+G IG+G FGDV++G+Y VAIK K+ D + FLQEA M
Sbjct: 588 IAXQDLEIGEAIGKGDFGDVYKGMYRGQ-----PVAIKQLKD--KDRGEQSFLQEASVMT 746
Query: 477 QFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVRKYS-LDLASLILYAYQLSTALA 535
H ++V+LIGV+ ++++ E G L +L+ R S + I +A A+
Sbjct: 747 SLRHDNLVRLIGVVLGETIFLVTEFMGKGNLVEYLRSRGRSVITKKDQINFATDTCAAME 926
Query: 536 YLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESI 594
YLESKR VHRD+AARNVLV + K+ DFGL+++ + + + K PIKW APE++
Sbjct: 927 YLESKRLVHRDLAARNVLVHDDGKAKVSDFGLAKFGD----FSQTSVKFPIKWTAPEAL 1091
Score = 77.8 bits (190), Expect(2) = 2e-44, Method: Compositional matrix adjust.
Identities = 33/81 (40%), Positives = 49/81 (60%)
Frame = +1
Query: 598 RFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTK 657
+FTS SD+W FG+ +WEI G P+ + DV+ +E G R+ P CPP +YS+M +
Sbjct: 1102 KFTSKSDMWSFGILLWEIYSFGRVPYPRIPLTDVVMHVERGYRMEAPEGCPPEIYSIMKQ 1281
Query: 658 CWAYDPSRRPRFTELKAQLST 678
W DP+ RP F + A+L+
Sbjct: 1282 AWELDPNERPTFKSVLARLNN 1344
>09007
Length = 1440
Score = 176 bits (445), Expect = 6e-44, Method: Compositional matrix adjust.
Identities = 94/274 (34%), Positives = 146/274 (53%), Gaps = 11/274 (4%)
Frame = -1
Query: 417 IQRERIELGRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTMR 476
I ++ + L + +G+G FG V Q I+ + + VA+K ++FL+E M+
Sbjct: 888 ISKDCVALSKSLGQGHFGTVRQAIWTAESGEKVQVAVKCLSKDKIHKDGQEFLKETAIMQ 709
Query: 477 QFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVRK-----YSLDLASLILYAYQLS 531
DH +IV++ GV+ +N IM + L +RS L+ K + L ++ Q+
Sbjct: 708 MLDHENIVRVYGVVMDNGA-DIMLVTELAPMRSLLECVKEVSARVDFSVPRLCDFSQQVC 532
Query: 532 TALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKL----PIK 587
++YLESKR VHRD+AARN+L+ S VK+ D G+S + Y S+ + +
Sbjct: 531 DGMSYLESKRLVHRDLAARNILLFSKSKVKISDVGVSGALGAGKEYYQSQQTIHLQNAVA 352
Query: 588 WMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIE--NGERLPMPP 645
W APES F+SASDVW FGV +WE HG +P+ G+ ++ ++ +RL P
Sbjct: 351 WCAPESFRNLCFSSASDVWAFGVLLWEFFTHGFQPWAGLNGQQIMEAVDAPQSQRLEQPD 172
Query: 646 NCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTI 679
CP Y++M KCW +P RRP F++L L I
Sbjct: 171 LCPKEYYAVMLKCWEQEPQRRPTFSQLFLTLPQI 70
>04852
Length = 1462
Score = 162 bits (410), Expect = 7e-40, Method: Compositional matrix adjust.
Identities = 88/263 (33%), Positives = 141/263 (53%), Gaps = 30/263 (11%)
Frame = +1
Query: 448 ALAVAIKTCKNCTSDSVREKFLQEALTMRQF----DHPHIVKLIGVITEN-PVWIIMELC 502
A VA+K ++ + + F+QE M+ H +IV +G T+ P+W+I+E
Sbjct: 19 ASTVAVKMLRDIVTAVEEQDFVQELQVMKAVKKMGSHINIVNFLGCCTQGGPLWVIVEFA 198
Query: 503 TLGELRSFLQ-----VRKYS-------------------LDLASLILYAYQLSTALAYLE 538
G LR FL+ + Y + +L+ YA+Q++ + +L
Sbjct: 199 KNGNLRDFLESCRDGINGYGKFVSPQDPGWYTKTPGGHVIRRKNLLSYAFQIARGMEFLA 378
Query: 539 SKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRR 598
S++ +HRD+AARNVLV+ +K+ DFGLSR Y K S G+LP+KWMAPE++ R
Sbjct: 379 SRKCIHRDLAARNVLVTEEHVLKIADFGLSR--TGDYYKKRSGGRLPVKWMAPEALFDMR 552
Query: 599 FTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGR-IENGERLPMPPNCPPTLYSLMTK 657
+T+ SDVW FGV +WEI G P+ + N ++ + +++ R+P P LY++M +
Sbjct: 553 YTTKSDVWSFGVVLWEIFSLGGMPYASIPNEELYSKLLDDAYRMPRPELASGNLYAIMER 732
Query: 658 CWAYDPSRRPRFTELKAQLSTIL 680
CW PS RP F++L + +L
Sbjct: 733 CWLNRPSDRPEFSQLVGHIDRLL 801
>14116
Length = 1017
Score = 147 bits (370), Expect = 3e-35, Method: Compositional matrix adjust.
Identities = 85/259 (32%), Positives = 140/259 (54%), Gaps = 19/259 (7%)
Frame = -1
Query: 380 EKQGMRTHAVSVSETDDYAEIID------------EEDTYTMPSTRDYEIQRERIELGRC 427
+ G RT+ + E +DY +D +ED + I RE + +G
Sbjct: 789 DSNGTRTYNLEARE-NDYFNRLDVQGAEAMPLLHIDEDMMKLIENESLLIDREFLTMGEE 613
Query: 428 IGEGQFGDVHQGIYMSPENPA-LAVAIKTCKNCTSDSVR-EKFLQEALTMRQFDHPHIVK 485
IG+G FG V +G PE + VA+KT N + + FLQEAL M+ F H +++
Sbjct: 612 IGKGNFGCVKRGFLTLPEQKGDILVAVKTLHNNNPREIELQSFLQEALIMKDFHHSNVLT 433
Query: 486 LIGV---ITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRF 542
LIG+ + + P+ +++ G+L ++++ ++ + LI+Y ++ + YL +F
Sbjct: 432 LIGICLNLDDMPL-VVLPFMKHGDLLTYIRDDQHQPTIKDLIMYGVDIARGMDYLAGLKF 256
Query: 543 VHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKA--SKGKLPIKWMAPESINFRRFT 600
VHRD+AARN ++ + VK+ DFGL+R + + YY + K KLP+KWMA ES+ +
Sbjct: 255 VHRDLAARNCMLDEDFHVKVADFGLARDIYEKEYYSSENKKAKLPVKWMALESLEKGNYD 76
Query: 601 SASDVWMFGVCMWEILMHG 619
S +DVW +GV +WE+L G
Sbjct: 75 SKTDVWSYGVVLWELLTRG 19
>07291
Length = 833
Score = 137 bits (346), Expect = 2e-32, Method: Compositional matrix adjust.
Identities = 62/164 (37%), Positives = 101/164 (61%), Gaps = 2/164 (1%)
Frame = +1
Query: 518 LDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYY 577
L + L+ + Q++ +AYL+ + VHR++AARN +V+ + ++L D+G++ + +YY
Sbjct: 40 LTVVQLLDFGRQIADGMAYLQEVKVVHRNLAARNCIVTEDGRLQLSDYGVTGSLFPQSYY 219
Query: 578 KA--SKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRI 635
A S + +KWMAPE+I+ F+S SDVW FGV +WE+L G+ P+ V+N+ ++ +
Sbjct: 220 TADDSPARDLVKWMAPETIDNFHFSSKSDVWAFGVVLWELLTRGITPYPDVENSSLLPYL 399
Query: 636 ENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTI 679
+ G R+ P P +Y +MT CW P +RP F EL QL T
Sbjct: 400 KEGHRMKKPKQSPEPVYEMMTACWNESPEQRPDFAELNDQLKTF 531
>17300
Length = 480
Score = 124 bits (310), Expect(2) = 6e-30, Method: Compositional matrix adjust.
Identities = 56/117 (47%), Positives = 78/117 (66%), Gaps = 3/117 (2%)
Frame = +1
Query: 530 LSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTY---YKASKGKLPI 586
+S+ + L +VHRD+AARN+LV+ K+ DFGLSR +E T Y GK+P+
Sbjct: 1 ISSGMGXLADMGYVHRDLAARNILVNEILVCKVADFGLSREIESDTTEGAYTTKGGKIPV 180
Query: 587 KWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPM 643
+W APE+I +R+FTSASDVW FGV MWE++ +G +P+ N DVI +E G RLP+
Sbjct: 181 RWTAPEAIAYRKFTSASDVWSFGVVMWEVMSYGERPYWNWSNQDVIKAVEKGYRLPL 351
Score = 26.6 bits (57), Expect(2) = 6e-30, Method: Compositional matrix adjust.
Identities = 10/35 (28%), Positives = 18/35 (51%)
Frame = +2
Query: 646 NCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTIL 680
+CP L+ LM W + S RP+ + + L ++
Sbjct: 356 DCPEALHQLMLDAWQKERSHRPKMSMVVKTLDKLI 460
>20640
Length = 1492
Score = 125 bits (314), Expect = 9e-29, Method: Compositional matrix adjust.
Identities = 55/139 (39%), Positives = 85/139 (61%), Gaps = 1/139 (0%)
Frame = +1
Query: 542 FVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASK-GKLPIKWMAPESINFRRFT 600
+VHRD+A RN LV + VK+ DFGL+R + YY+ S+ +PI+WM E+I + +F+
Sbjct: 7 YVHRDLATRNCLVGHDLVVKISDFGLARSVHSVDYYRGSEHDAIPIRWMPLEAILYNKFS 186
Query: 601 SASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWA 660
+ SDVW FGV +WEI ++P+ G+ + +V+ ++ G+ L P PP +Y LM +CW
Sbjct: 187 TQSDVWSFGVVLWEIFAFALQPYYGLTHEEVVRFVKEGKVLACPERTPPPMYELMKQCWH 366
Query: 661 YDPSRRPRFTELKAQLSTI 679
P+ RP F L L +
Sbjct: 367 RRPATRPSFHTLHKTLENM 423
>07940
Length = 1336
Score = 119 bits (297), Expect = 9e-27, Method: Compositional matrix adjust.
Identities = 54/111 (48%), Positives = 77/111 (69%), Gaps = 1/111 (0%)
Frame = -3
Query: 523 LILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYY-KASK 581
LI YAYQ++ + YL SK+ +HRD+AARNVLV+ +K+ DFGL+R ++ YY K +
Sbjct: 341 LISYAYQVARGMEYLASKQCIHRDLAARNVLVAEEYVLKIADFGLTRNLQQFDYYRKTTD 162
Query: 582 GKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVI 632
G+LP+KWMAPE++ R++TS SDVW +GV +WEI G P+ V D+
Sbjct: 161 GRLPVKWMAPEALFDRKYTSKSDVWSYGVLLWEIFTLGGNPYPSVPVEDLF 9
Score = 58.5 bits (140), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 37/114 (32%), Positives = 59/114 (51%), Gaps = 4/114 (3%)
Frame = -3
Query: 403 EEDTYTMPSTRDYEIQRERIELGRCIGEGQFGDVHQGIYMS--PENPALAVAIKTCKNCT 460
E Y +P +E RER+ LG +GEG FG V +G M +N ++ VA+K K
Sbjct: 893 EVSEYDLPLDAKWEFPRERLVLGDRLGEGAFGLVMKGEAMGIFKDNNSVTVAVKMLKEDA 714
Query: 461 SDSVREKFLQEALTMRQF-DHPHIVKLIGVITE-NPVWIIMELCTLGELRSFLQ 512
+D ++E M+ H +I+ L+G T+ +++I+E G LR FL+
Sbjct: 713 TDREMMDLIREMEMMKVIGKHKNIINLLGCCTQRGALYVIVEFAPHGNLRDFLK 552
>08294
Length = 1849
Score = 117 bits (293), Expect = 2e-26, Method: Compositional matrix adjust.
Identities = 67/209 (32%), Positives = 113/209 (54%), Gaps = 12/209 (5%)
Frame = +2
Query: 481 PHIVKLIGVITE-NPVWIIMELCTLGELRSFL-----------QVRKYSLDLASLILYAY 528
P+IV +GV E P ++I E C G+L+ FL R +L L+ +
Sbjct: 887 PNIVHFMGVCREAEPHFLITEYCDWGDLKQFLLATRNDNGRGRGTRVPALALSQKLGMGQ 1066
Query: 529 QLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKW 588
Q++ + L ++ VH D+AARNVL++S +K+ LS + S YY + +P++W
Sbjct: 1067 QVAAGMEALSNQGLVHGDLAARNVLLTSRMQLKVARPALSGDVYASEYYPLHQRLVPLRW 1246
Query: 589 MAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCP 648
+ PE + T+ DVW FGV +WE+L P++ + + +V+ +++ + P+ P
Sbjct: 1247 LPPEGVLEDSATTCGDVWAFGVFLWEVLQLADLPYRLMSDEEVLRSLQHSQAALDSPDAP 1426
Query: 649 PTLYSLMTKCWAYDPSRRPRFTELKAQLS 677
P L SL+ +C A PS+RP F+E+ + LS
Sbjct: 1427 PALLSLLQRCTAQQPSQRPPFSEICSVLS 1513
>18996
Length = 491
Score = 111 bits (277), Expect = 2e-24, Method: Compositional matrix adjust.
Identities = 56/136 (41%), Positives = 82/136 (60%), Gaps = 6/136 (4%)
Frame = +2
Query: 543 VHRDIAARNVLVSSNDCVKLGDFGLSRYME-DSTYYKASKGKLPIKWMAPESINFRRFTS 601
+HRD+AARN+LV + CVK+ DFGL+++ D YY S+ +PIKW +PE+I +F+S
Sbjct: 2 IHRDLAARNILVDRS-CVKISDFGLAQFANADGYYYGISQRDIPIKWYSPEAIETCKFSS 178
Query: 602 ASDVWMFGVCMWEILMHG----VKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYS-LMT 656
SDVW +GV ++E+ G + P + + + R+ GERLP P C +YS LM
Sbjct: 179 YSDVWSYGVTLFEMFSRGEIPNLLPGHDLTQEEFLNRLRKGERLPKPELCSDFVYSELMR 358
Query: 657 KCWAYDPSRRPRFTEL 672
CW P RP F ++
Sbjct: 359 PCWHEMPKSRPTFHQI 406
>14477
Length = 493
Score = 108 bits (271), Expect = 1e-23, Method: Compositional matrix adjust.
Identities = 62/169 (36%), Positives = 102/169 (60%), Gaps = 2/169 (1%)
Frame = -1
Query: 416 EIQRERIELGRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSD-SVREKFLQEALT 474
+IQ + ++LG G FG V +G+ ++ + VAIK KN D SV+ + ++EA
Sbjct: 490 QIQMDELKLG----AGNFGSVMKGVC-RLDDREIPVAIKVLKNADLDPSVQSELIKEAEV 326
Query: 475 MRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTAL 534
M++ DH HIV+LIG+ + +++EL LG L FL K+ L L +++ +Q+S +
Sbjct: 325 MKKMDHMHIVRLIGLCEGETMMLVLELAKLGPLNKFLPKNKH-LPLWNILELMWQVSQGM 149
Query: 535 AYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYM-EDSTYYKASKG 582
YLE+ +FVHRD+AARN+L+ K+ DFG+S+ + ++ YY A +
Sbjct: 148 EYLEANKFVHRDLAARNILLCDEHFAKISDFGMSKTLSRENNYYMAQEA 2
>17253
Length = 483
Score = 96.7 bits (239), Expect = 5e-20, Method: Composition-based stats.
Identities = 55/153 (35%), Positives = 88/153 (57%), Gaps = 15/153 (9%)
Frame = -1
Query: 451 VAIKTCKNCTSDSVREKFLQEALTMRQFD-HPHIVKLIGVIT-ENPVWIIMELCTLGELR 508
VA+KT +D+ + +FL+E MR+ HP++V +G T +P I+ME C G+L
Sbjct: 459 VAVKTHNEAATDAEKSEFLRELSIMRKLPRHPNVVSFMGCCTMSDPALILMEFCCHGDLL 280
Query: 509 SFLQVRK---------YSLDLASLILYAYQLSTA--LAYLESKRFVHRDIAARNVLVSSN 557
SFL+ R+ + DL + +++ L A +A++ + + VHRD+AARNVL+S
Sbjct: 279 SFLRKRRPDRTVFLTSTANDLTARDFFSFALHVARGMAHVANNKIVHRDVAARNVLISER 100
Query: 558 DCVKLGDFGLSRYMEDS--TYYKASKGKLPIKW 588
+ K+ DFGLSR + D Y S+ LP++W
Sbjct: 99 NVCKVSDFGLSRRVGDQNDVYEIVSRRPLPLRW 1
>22005
Length = 873
Score = 95.9 bits (237), Expect = 8e-20, Method: Compositional matrix adjust.
Identities = 78/246 (31%), Positives = 118/246 (47%), Gaps = 55/246 (22%)
Frame = +1
Query: 426 RCIGEGQFGDVHQGIYMS---------PEN-PALAVAIKTCKNCTSDSVREKFLQEALTM 475
R IG+G FG V + ++ PE P L K K S+ ++ F +EA M
Sbjct: 1 RDIGQGAFGRVSKLKFLGLASLVGELIPEKRP*LL*--KMLKEDASEDLQSDFEREASLM 174
Query: 476 RQFDHPHIVKLIGVIT-ENPVWIIMELCTLGELRSFLQV---RKYSL------------- 518
FDHP+IVKL+GV P+ ++ E + G+L FL++ Y+L
Sbjct: 175 ADFDHPNIVKLLGVCAIGKPMCLLFEFMSKGDLNDFLRLCSPENYNLPVSRSQNLVVDLE 354
Query: 519 ---------------------DLASLI-----LY-AYQLSTALAYLESKRFVHRDIAARN 551
D + ++ LY + Q+S +AYL K +VHRD+A R
Sbjct: 355 DGLRVEVEAEECEKDTQSEDRDCSGMLXTKDQLYISQQISAGMAYLAQKDYVHRDLATRT 534
Query: 552 VLVSSNDCVKLGDFGLSRYMEDSTYYKAS-KGKLPIKWMAPESINFRRFTSASDVWMFGV 610
V + + DFGL+R + YY+ S + +PI+WM E+I + +F++ SDVW FGV
Sbjct: 535 VXSRTT*-S*ISDFGLARSVHSVDYYRGSEQDAIPIRWMPLEAILYSKFSTQSDVWSFGV 711
Query: 611 CMWEIL 616
+WEIL
Sbjct: 712 VLWEIL 729
>18921
Length = 697
Score = 95.5 bits (236), Expect = 9e-20, Method: Compositional matrix adjust.
Identities = 68/232 (29%), Positives = 114/232 (49%), Gaps = 4/232 (1%)
Frame = +2
Query: 424 LGRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHI 483
LG+ +GEG +G V + ++ LA+ K D+ ++ ++E M+Q D +I
Sbjct: 44 LGK-LGEGSYGSVFKSLHKE-TGQVLAI-----KQVPVDTDLQEIIKEISIMQQCDSKYI 202
Query: 484 VKLIGVITENP-VWIIMELCTLGELRSFLQVRKYSL---DLASLILYAYQLSTALAYLES 539
VK G +N +WI+ME C G + +++R +L ++A+++ Y + L YL S
Sbjct: 203 VKYYGSYFKNTDLWIVMEYCGAGSVSDIMRLRNKTLVEREIATILYYTLK---GLXYLHS 373
Query: 540 KRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRF 599
+R +HRDI A N+L+++ KL DFG++ + D+ + + P WMAPE I +
Sbjct: 374 RRKIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTPY-WMAPEVIQEIGY 550
Query: 600 TSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTL 651
+D+W G+ E + G P I G+ P N PP L
Sbjct: 551 DCVADIWSLGITALE-MAEGKPPVMETS-------IL*GQSS*FPTNAPPPL 682
>17637
Length = 447
Score = 90.1 bits (222), Expect = 5e-18, Method: Compositional matrix adjust.
Identities = 46/128 (35%), Positives = 70/128 (54%), Gaps = 1/128 (0%)
Frame = +1
Query: 551 NVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKL-PIKWMAPESINFRRFTSASDVWMFG 609
N ++ VKL D LSR + Y G+ PIKW++ E++ + SDVW FG
Sbjct: 1 NCVIDDQLRVKLTDSALSRDLFSGDYNCLGDGEYRPIKWLSLEALQKSHYNEGSDVWSFG 180
Query: 610 VCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRF 669
V MWE+ G P+ + ++ +++G RL P NCP L+++M CWA P+ RP F
Sbjct: 181 VLMWEMCTLGKLPYAEIDPYEMEHYLKDGYRLAQPFNCPDELFTIMAYCWASMPAERPSF 360
Query: 670 TELKAQLS 677
++L+ LS
Sbjct: 361 SQLQICLS 384
>13305
Length = 549
Score = 87.4 bits (215), Expect = 3e-17, Method: Composition-based stats.
Identities = 37/100 (37%), Positives = 57/100 (57%)
Frame = +2
Query: 583 KLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLP 642
++PI+WMA ES+ +T+ SDVW FGV +WEI G P+ + +++G RL
Sbjct: 8 RVPIRWMAVESLFNNTYTTQSDVWSFGVVLWEIFTLGGTPYSSTDTQQLFAFLKDGYRLK 187
Query: 643 MPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEE 682
P C Y++M +CW + RRP F EL +L +L++
Sbjct: 188 RPKLCDQNTYAMMLQCWNENAQRRPTFPELCGRLQRMLDD 307
>00300
Length = 2318
Score = 87.0 bits (214), Expect = 4e-17, Method: Compositional matrix adjust.
Identities = 74/276 (26%), Positives = 122/276 (44%), Gaps = 13/276 (4%)
Frame = -1
Query: 410 PSTRDYEIQRERIEL----GRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSD--S 463
P DY I R+ G IGEGQFG V+ + MS +A+K K +D
Sbjct: 1700 PREPDYRINVRRVNFRWQRGNKIGEGQFGKVYTAVNMST---GELMALKEMKFQPNDLQQ 1530
Query: 464 VREKFLQEALTMRQFDHPHIVKLIGV-ITENPVWIIMELCTLGELRSFLQVRKYSLDLAS 522
+RE E H ++VK GV + ++ + + ME C G + + K L
Sbjct: 1529 LRE-MCDEIKIFEGIQHENLVKYYGVEVHKDEMLMFMEYCDTGTIE---EAAKMGLPEYL 1362
Query: 523 LILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKG 582
+ Y ++ A+ +L VHRDI N+ ++SN VKLGDFG S ++ T
Sbjct: 1361 IRRYTREIVLAVNHLHENSIVHRDIKGANIFLTSNGHVKLGDFGCSVKLKSHTTMPGEFH 1182
Query: 583 KL--PIKWMAPESINFRR---FTSASDVWMFGVCMWEILMHGVKPFQGVKNN-DVIGRIE 636
L +MAPE + A+D+W G + E+ G +P+ + NN ++ ++
Sbjct: 1181 NLVGTTAYMAPEVFTQNDQGGYGRAADIWSLGCVVIEMAT-GKRPWHDLDNNYQIMYKVG 1005
Query: 637 NGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTEL 672
G + +P + + +DP++R ++L
Sbjct: 1004 IGHKPAVPDSLSVEGKHFLDLIMCHDPAQRALASQL 897
>01718
Length = 959
Score = 86.7 bits (213), Expect = 4e-17, Method: Compositional matrix adjust.
Identities = 73/271 (26%), Positives = 111/271 (40%), Gaps = 14/271 (5%)
Frame = +3
Query: 428 IGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLI 487
IG G F +V + + + + K T S R L+E + + H +I++ +
Sbjct: 171 IGAGFFSEVFKVTH------RITGQVMALKMNTMTSNRHNMLREVQLLNRLQHANILRFM 332
Query: 488 GV-ITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRD 546
GV + E + + E G L L+ + L I L+ L YL S RF+HRD
Sbjct: 333 GVCVHEGQLHALTEYIPSGNLEQLLEKKDEELPWTQRIQLTLGLARGLDYLHSTRFIHRD 512
Query: 547 IAARNVLVSSNDC----VKLGDFGLSRYMEDSTYYKASKGKLPI----KWMAPESINFRR 598
+ ++N+L+ D + DFGL+ + D K KLP WMAPE +N
Sbjct: 513 LTSKNILIRREDNHGYHAVIADFGLATKIPDPL----DKEKLPTVGSPYWMAPEVLNGHF 680
Query: 599 FTSASDVWMFGVCMWEILMH-----GVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYS 653
+ +D++ G+ M EI + P D + E M CP
Sbjct: 681 YNERADLFSVGIIMCEITARIPADPDIMPRMNNFGVDYVALSE------MISYCPLDYLQ 842
Query: 654 LMTKCWAYDPSRRPRFTELKAQLSTILEEEK 684
L KC DP +RPR E+ L I + K
Sbjct: 843 LAFKCCQVDPQKRPRGVEIIEWLEKIFKNLK 935
>19301
Length = 712
Score = 82.8 bits (203), Expect = 7e-16, Method: Compositional matrix adjust.
Identities = 54/170 (31%), Positives = 87/170 (51%), Gaps = 1/170 (0%)
Frame = +2
Query: 400 IIDEEDTYTMPSTRDYEIQRERIELGRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNC 459
II + + D+EI E I +G G G V G + E VA+K ++
Sbjct: 245 IIGKAAAAELKQQDDWEIPFESITDLEWLGSGAQGAVFLGKLCAEE-----VAVKKVRDI 409
Query: 460 TSDSVREKFLQEALTMRQFDHPHIVKLIGVITENPVW-IIMELCTLGELRSFLQVRKYSL 518
+R +R+ +HP+I+ GV T+ P + IIME C G+L L+ K +
Sbjct: 410 KETDIR--------NLRKLNHPNIISFKGVCTQAPCYCIIMEYCPYGQLYEVLRDGK-EI 562
Query: 519 DLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLS 568
A ++ ++ Q+++ + YL S + +HRD+ + NVLV+ ND VK+ DFG S
Sbjct: 563 PPALVLDWSKQIASGMNYLHSHKIIHRDLKSPNVLVAKNDVVKISDFGTS 712
>12721
Length = 821
Score = 77.8 bits (190), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 66/247 (26%), Positives = 103/247 (41%), Gaps = 8/247 (3%)
Frame = +1
Query: 428 IGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLI 487
IGEG G V I S + +AV + RE E + MR + HP+IV++
Sbjct: 112 IGEGSTGIV--CIATSRDGRQMAVKKMDLRK---QQRRELLFNEVVVMRDYHHPNIVEMY 276
Query: 488 G-VITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRD 546
+ + +W++ME G L V +D + ALA+L + +HRD
Sbjct: 277 NSYLVNDELWVVMEFMEGGALTDI--VTNNRMDEVQIATVCRACLKALAFLHANGVIHRD 450
Query: 547 IAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVW 606
I + ++L+S + VKL DFG + + S P WMAPE I+ + D+W
Sbjct: 451 IKSDSILLSHDGKVKLXDFGFCAQVTQDLQKRKSLVGTPY-WMAPEVISRLPYGPEVDIW 627
Query: 607 MFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPP-------NCPPTLYSLMTKCW 659
G+ + E ++ PF + RI + MPP P L + +
Sbjct: 628 SLGIMVME-MIDAEPPFFNEPPLQAMRRIRD-----MPPPKLRNTHKISPRLQGFIDRML 789
Query: 660 AYDPSRR 666
DP +R
Sbjct: 790 VRDPHQR 810
>14420
Length = 528
Score = 74.7 bits (182), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 45/167 (26%), Positives = 78/167 (46%), Gaps = 1/167 (0%)
Frame = +2
Query: 458 NCTSDSVREKFLQEALTMRQFDHPHIVK-LIGVITENPVWIIMELCTLGELRSFLQVRKY 516
N + +E + E L MR+ +P+IV L + +W++ME G L V +
Sbjct: 11 NLSQQPKKELIINEILVMRENQNPNIVNYLDSYLVGEELWVVMEFLAGGSLTDV--VTET 184
Query: 517 SLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTY 576
+D + + AL +L + +HRDI + N+L+ + VKL DFG +
Sbjct: 185 CMDEGQIAAVCRECLQALEFLHENQVIHRDIKSDNILLGMDGSVKLTDFGFCAQLSPEQS 364
Query: 577 YKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPF 623
+++ P WMAPE + +++ D+W GV E ++ G P+
Sbjct: 365 KRSTMVGTP-YWMAPEVVTRKQYGPTVDIWSLGVMCIE-MIEGEPPY 499
>13592
Length = 980
Score = 72.8 bits (177), Expect = 7e-13, Method: Compositional matrix adjust.
Identities = 67/257 (26%), Positives = 119/257 (46%), Gaps = 9/257 (3%)
Frame = +2
Query: 428 IGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTMRQ-FDHPHIVKL 486
IG+G+FG V+ + N +A+K ++ K + E L + + H ++V+
Sbjct: 8 IGQGRFGKVYTAV---NNNTGELMAMKEIAIQPGETRALKNVAEELKILEGIKHKNLVRY 178
Query: 487 IGV-ITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHR 545
G+ + + I MELC+ G L S +++ L A + QL + +A L VHR
Sbjct: 179 YGIEVHREELLIFMELCSEGTLESLVELTG-GLPEALSRRFTAQLLSGVAELHKHGIVHR 355
Query: 546 DIAARNV-LVSSNDCVKLGDFGLSRYMEDSTYYKAS-KGKLPIK-WMAPE---SINFRRF 599
DI N+ LV ++ +KLGDFG + ++ T +G + + +MAPE N
Sbjct: 356 DIKTANIFLVDGSNSLKLGDFGSAVKIQAHTTVPGELQGYVGTQAYMAPEVFTKTNSDGH 535
Query: 600 TSASDVWMFGVCMWEILMHGVKPFQGVKNN-DVIGRIENGERLPMPPNCPPTLYSLMTKC 658
+D+W G + E + G +P+ +N ++ ++ GE+ P + + + C
Sbjct: 536 GRLADIWSVGCVVVE-MASGKRPWAQFDSNFQIMFKVGMGEKPQAPESLSQEGHDFIDHC 712
Query: 659 WAYDPSRRPRFTELKAQ 675
+DP +R EL Q
Sbjct: 713 LQHDPKQRLSAIELLEQ 763
>27546
Length = 426
Score = 69.7 bits (169), Expect = 6e-12, Method: Composition-based stats.
Identities = 35/114 (30%), Positives = 65/114 (57%), Gaps = 1/114 (0%)
Frame = -1
Query: 462 DSVREKFLQEALTMRQFDHPHIVKLIGVITENP-VWIIMELCTLGELRSFLQVRKYSLDL 520
D V++ F +E + + DHP+I+++ ++ P ++I M G++ S ++ + +D
Sbjct: 357 DFVKKFFPRELEILTRLDHPNIIQIHSILQRGPKIFIFMRYAEKGDMLSHIK-KTGPIDE 181
Query: 521 ASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDS 574
A ++ +Q++ AL YL S HRD+ N+L+S VK+ DFG +RY D+
Sbjct: 180 AQTKVWFFQMAKALQYLHSHDIAHRDLKCENILLSKRLNVKIADFGFARYCRDA 19
>30755
Length = 1137
Score = 68.9 bits (167), Expect = 9e-12, Method: Compositional matrix adjust.
Identities = 44/143 (30%), Positives = 76/143 (53%), Gaps = 1/143 (0%)
Frame = +2
Query: 525 LYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKL 584
Y ++ +AL YL S+ ++RD+ N+L+ + +K+ DFGL + ED TY + +K
Sbjct: 44 FYGAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCK--EDITYGRTTKTFC 217
Query: 585 PI-KWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPM 643
+++APE ++ + A D W GV M+E++ G PF +++DV+ + E +
Sbjct: 218 GTPEYLAPEVLDDNDYGRAVDWWGTGVVMYEMIC-GRLPFYN-RDHDVLFTLILVEDVKF 391
Query: 644 PPNCPPTLYSLMTKCWAYDPSRR 666
P N SL++ A DP R
Sbjct: 392 PRNITDEAKSLLSGLLAKDPRNR 460
>00715
Length = 1788
Score = 67.8 bits (164), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 59/253 (23%), Positives = 110/253 (43%), Gaps = 34/253 (13%)
Frame = +1
Query: 449 LAVAIKTCKNCTSDSVREKFLQEALTMR-QFDHPHIVKLIGVIT----ENPVWIIMELCT 503
+AV I ++ ++R+ + E L R H ++V ++G + E+ W+ ME
Sbjct: 7 VAVKIYHKRSSNPRALRQSYSNELLAFRCGLRHVNVVSILGATSLHRFEDGAWLAMEYVG 186
Query: 504 LGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLG 563
L++ L + +D + + A Q++ L YL S VH D+ N L++ + +++
Sbjct: 187 PLNLQTILNDHQQDIDSSMRLSLALQMARGLHYLHSINIVHLDLKPANCLLTRDLKLRIA 366
Query: 564 DFGLSRYM-------------------EDSTYYKASKGKLP--IKWMAPESINFRRFTSA 602
DFG + E + A K +L + + APE + + +
Sbjct: 367 DFGCCHQLTPTGLDMGEREGGMAGNELELTPVQGAWKNELAGTLAYRAPELLKGLQPSVR 546
Query: 603 SDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPT--------LYSL 654
SDV+ G+ +W++ P++GV + V+ ++ + + P PP P T L
Sbjct: 547 SDVYSLGITLWQMCTRQ-GPYEGVPAHAVVYQVVSKDLRPCPP--PSTEDDPFEVMFRDL 717
Query: 655 MTKCWAYDPSRRP 667
T+CWA RP
Sbjct: 718 YTQCWARRVEDRP 756
>13066
Length = 551
Score = 67.0 bits (162), Expect = 4e-11, Method: Compositional matrix adjust.
Identities = 49/174 (28%), Positives = 82/174 (47%), Gaps = 10/174 (5%)
Frame = +3
Query: 446 NPALAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITENPV-WIIMELCTL 504
N LA I + D V + F +E + + DHP+I+++ ++ P +I M
Sbjct: 51 NIKLACKIIDKEKAPVDFVEKFFPRELDLLTKLDHPYIIQIHSILQRXPKNFIFMRFAER 230
Query: 505 GELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGD 564
G+L +++Q + + + I + YQ++TAL YL S HRD+ N+L+SS+ VKL D
Sbjct: 231 GDLLTYIQEVGFVKEKQAKIWF-YQMTTALNYLHSYDVAHRDLKCENILLSSHFNVKLAD 407
Query: 565 FGLS---------RYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFG 609
FG + +YM + A+ I + AP + +D W G
Sbjct: 408 FGFACACITESGEKYMSRTYCGSAAYAAPEIVYGAPYA------PKVADAWSLG 551
>31885
Length = 529
Score = 67.0 bits (162), Expect = 4e-11, Method: Compositional matrix adjust.
Identities = 46/148 (31%), Positives = 77/148 (52%), Gaps = 6/148 (4%)
Frame = -2
Query: 475 MRQFDHPHIVKL-IGVITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTA 533
+ + DHP +V L E ++++++L G+LR +Q ++ S + Y QL+
Sbjct: 510 LTRLDHPFLVNLWYAFQDEEDLFMVVDLFLGGDLRYHMQ-QEVSFREDCVKFYLCQLALV 334
Query: 534 LAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPE- 592
L YL S++ VHRDI N+L+ + DF ++ +ED ++ G P +MAPE
Sbjct: 333 LDYLRSQKIVHRDIKPDNILLDEQGHCHVTDFNIATQLEDDELATSTSGTRP--YMAPEV 160
Query: 593 ---SINFRR-FTSASDVWMFGVCMWEIL 616
+IN RR + D W GV ++E+L
Sbjct: 159 YGVAINERRGYGFPVDWWSLGVSLFELL 76
>07833
Length = 1504
Score = 66.2 bits (160), Expect = 7e-11, Method: Compositional matrix adjust.
Identities = 53/217 (24%), Positives = 99/217 (45%), Gaps = 7/217 (3%)
Frame = -3
Query: 460 TSDSVREKFLQEALTMRQFDHPHIVKLIGVITENP-VWIIMELCTLGELRSFLQVRK-YS 517
+ + F++E +R F+HP+++ ++ + P + +I + G L + L
Sbjct: 1502 VTKRITRDFMEEFPRLRIFNHPNVLPVLACCNQPPNLVLISQFMPFGSLYNTLHGESGIV 1323
Query: 518 LDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYY 577
+D + +A ++ + +L S + N L++S + D M D +
Sbjct: 1322 VDQNQSLRFAMDIARGMEFLHSM-----EPTIPNFLLTSKHVMIDEDLTARINMADYCFS 1158
Query: 578 KASKGKL-PIKWMAPESINFRR---FTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIG 633
KGK+ WMAPE++ R T A+D+W F + MWE+ V PF + + +V
Sbjct: 1157 FHEKGKVYSPAWMAPEALQRRPDDINTRAADMWSFAILMWELETREV-PFAELSSMEVGM 981
Query: 634 RIE-NGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRF 669
++ G R+ +PP + L+ C +P +RPRF
Sbjct: 980 KVALEGLRISIPPGISLHMSRLIKICMNEEPGKRPRF 870
>09606
Length = 1300
Score = 65.1 bits (157), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 68/292 (23%), Positives = 118/292 (40%), Gaps = 37/292 (12%)
Frame = -3
Query: 428 IGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLI 487
+G+G+ +++G N I+ CK R + HP++V+
Sbjct: 1091 LGKGEHSIIYKGRRKGTINFVAIHCIEKCK-------RPEVTNTVRMTHDISHPNVVQFH 933
Query: 488 GVI-TENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRD 546
T N +W+++ELCT G L L + + L S+ + L T L Y+ S + D
Sbjct: 932 EWYETSNHLWLVVELCTGGSLADIL-AQDHHLPETSIRDFGIHLVTGLHYIHSLGILFHD 756
Query: 547 IAARNVLVSSNDCVKLGDFGLSRY----MEDSTYYKASKG-------------KLPIK-- 587
+ VL+ ++ +K DFGLS+ +E+ + A G ++P
Sbjct: 755 LRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQWNIQSAEEMMKQVPTSGS 576
Query: 588 --WMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIEN-------- 637
+MAPE + SD+W G +E + G PF G + ++ N
Sbjct: 575 PTYMAPEVFQGAEPSIMSDLWALGCVFYE-MFSGHPPFLGETYDITKDKVLNKEFPLPKV 399
Query: 638 -GERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTEL------KAQLSTILEE 682
G RL P+ P +L+ D +RR + L + LS++++E
Sbjct: 398 KGSRLSAKPS--PEFLNLLESLLQKDSTRRLSWASLVKHAFWQGGLSSLVKE 249
>14126
Length = 1265
Score = 64.7 bits (156), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 72/296 (24%), Positives = 135/296 (45%), Gaps = 19/296 (6%)
Frame = +3
Query: 369 ALPSIPKLANSEKQGMRTH-AVSVSETDDYAEIIDEEDTYTMPSTRDYEIQRERIELGRC 427
ALP+I ++ +E+ +T AV +T + D + +R + ++ E
Sbjct: 33 ALPTIFRIC*NEESSPKTSPAVRSMKTAISPKGRDGQSESAAKMSRRRDSTEQKYEEVAV 212
Query: 428 IGEGQFGDVHQGIYMSPENPALAVAIKTCK-NCTSDSVREKFLQEALTMRQ---FDHPHI 483
IG G +G V++ + N VA+K + N T + + ++E ++Q ++HP++
Sbjct: 213 IGNGAYGTVYKARDL--RNQGEFVAMKRIRLNNTEEGMPMMAIREISMLKQLEQYEHPNV 386
Query: 484 VKLIGVITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYA--------------YQ 529
V+L+ V + N + T E+R L DLA+ + Q
Sbjct: 387 VRLLDV-SHNTI-------TDREIRLNLVFEYIEHDLATYLAKCPSPGLGPDRIKDLMLQ 542
Query: 530 LSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWM 589
L + +L S R VHRD+ +N+L+S + +KL DFGL+R S + + + + +
Sbjct: 543 LLNGVDFLHSNRIVHRDLKPQNLLISKDGRLKLADFGLARIY--SFHMALTTVVVTLWYR 716
Query: 590 APESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPP 645
+PE + + ++ D+W G C++ L F+G D + +I E + +PP
Sbjct: 717 SPEVLMQAEYGTSVDIWSCG-CIFAELFTRRALFKGSSEFDQLKKI--FEVIGLPP 875
>01060
Length = 1800
Score = 62.8 bits (151), Expect = 7e-10, Method: Compositional matrix adjust.
Identities = 48/196 (24%), Positives = 100/196 (51%), Gaps = 6/196 (3%)
Frame = +1
Query: 428 IGEGQFGDVHQGIYMSPENPALAVAIKTCK-NCTSDSVREKFLQEALTMRQFDHPHIVKL 486
IGEG +G V++ + + +A+K + + D V ++E +R+ H +IV L
Sbjct: 97 IGEGTYGVVYKCRHRATGR---KLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTNIVCL 267
Query: 487 IGVITENP-VWIIMELCTLGELRSFLQV--RKYSLDLASLILYAYQLSTALAYLESKRFV 543
VI E+ ++++ E ++ +L+ ++ LD + Y +Q+ T + + +R V
Sbjct: 268 EDVIMEDERLFLVFEFLSM-DLKMYIDKFPEGVVLDRRLVKSYVFQIVTGIXFCHQRRIV 444
Query: 544 HRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWM-APESI-NFRRFTS 601
HRD+ +N+L++ +K+ DFG++R + +A ++ W APE + ++++
Sbjct: 445 HRDLKPQNLLINHTGAIKIADFGMARTF--ALPVRAYTHEVVTLWYRAPEILMGASKYST 618
Query: 602 ASDVWMFGVCMWEILM 617
DVW G ++L+
Sbjct: 619 PVDVWSIGTIFADMLI 666
>19094
Length = 898
Score = 61.6 bits (148), Expect = 1e-09, Method: Composition-based stats.
Identities = 34/114 (29%), Positives = 62/114 (54%), Gaps = 3/114 (2%)
Frame = +1
Query: 505 GELRSFLQVRKYSL---DLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVK 561
G + +++R +L ++A+++ Y + L YL S+R +HRDI A N+L+++ K
Sbjct: 10 GSVSDIMRLRNKTLVEREIATILYYTLK---GL*YLHSRRKIHRDIKAGNILLNNEGHAK 180
Query: 562 LGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEI 615
L DFG++ + D+ + + P WMAPE I + +D+W G+ E+
Sbjct: 181 LADFGVAGQLTDTMAKRNTVIGTPY-WMAPEVIQEIGYDCVADIWSLGITALEM 339
>13212
Length = 1067
Score = 61.2 bits (147), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 51/196 (26%), Positives = 84/196 (42%), Gaps = 18/196 (9%)
Frame = -1
Query: 495 VWIIMELCTL---GELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARN 551
VW I+++ + G L S + + + A + +++ AL +L +HRDI A N
Sbjct: 1067 VWXIVDVFRVLWWGALDSIMVDLEKPMTEAQICYVCHEMCMALDFLHRHHVIHRDIKAGN 888
Query: 552 VLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAP-----ESINFRRFTSASDVW 606
VL++ + VKL DFG+S + + + P WMAP E++ + +D+W
Sbjct: 887 VLLTIDGEVKLADFGVSAKNTQTQQKRDTFIGTPY-WMAPEVVLCETLKDTPYDFKADIW 711
Query: 607 MFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTL----------YSLMT 656
GV + E P + + V+ +I + PPTL +
Sbjct: 710 SLGVTLIE-FAQIEPPNKEMHPMRVLIKIHKSD--------PPTLEKPKKWTKLFKDFIA 558
Query: 657 KCWAYDPSRRPRFTEL 672
KC DP+ RP EL
Sbjct: 557 KCLVKDPNLRPTAAEL 510
>29581
Length = 1278
Score = 60.1 bits (144), Expect = 5e-09, Method: Compositional matrix adjust.
Identities = 49/164 (29%), Positives = 78/164 (47%), Gaps = 8/164 (4%)
Frame = -2
Query: 463 SVREKFLQEALTMRQFDHPHIVKLIGVI---TENPVWIIMELCTLGELRSFLQVRKYSLD 519
VR FL L +R H +IV+L V+ + + ++++ME C +L S L
Sbjct: 1211 CVRSTFL---LNLR---HQNIVQLQEVVVGKSLDSLFLVMEYCE-QDLASLLDNMPAPFS 1053
Query: 520 LASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKA 579
+ + QL L YL +HRD+ N+L++ CVK+ DFGL+R Y K
Sbjct: 1052 ESQVKCIVLQLLKGLRYLHEAFIIHRDLKVSNLLMTDKGCVKIADFGLAR-----NYGKP 888
Query: 580 SKGKLP----IKWMAPESI-NFRRFTSASDVWMFGVCMWEILMH 618
K P + + APE + + ++A D+W G + E+L H
Sbjct: 887 QKPMTPKVVTLWYRAPELLFGSKTHSTAIDMWSAGCILGELLGH 756
>01756
Length = 1858
Score = 58.9 bits (141), Expect = 9e-09, Method: Compositional matrix adjust.
Identities = 49/204 (24%), Positives = 90/204 (44%), Gaps = 16/204 (7%)
Frame = -3
Query: 428 IGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKF----LQEALTMRQFDHPHI 483
IG+G FG+V + + VA+K D+ +E F L+E ++ +H ++
Sbjct: 1718 IGQGTFGEVFKA---RCKKTKQVVAMK---KVLMDNEKEGFPITALREIKILQLLNHENV 1557
Query: 484 VKLIGVIT---------ENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTAL 534
V LI + + ++ +++ E C +L L +L + QL L
Sbjct: 1556 VDLIEICSTKATSANRYKSMFYLVFEFCE-HDLAGLLSNMSVVFNLPEIKEVMKQLMNGL 1380
Query: 535 AYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSR-YMEDSTYYKASKGKLPIKWMAPES 593
Y+ + +HRD+ A N+L++ +KL DFGL+R + + ++ W P
Sbjct: 1379 YYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRPPE 1200
Query: 594 INF--RRFTSASDVWMFGVCMWEI 615
+ R +++A D W G M E+
Sbjct: 1199 LLLGDRNYSTAIDQWGAGCIMAEM 1128
>19761
Length = 473
Score = 58.9 bits (141), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 34/130 (26%), Positives = 67/130 (51%), Gaps = 8/130 (6%)
Frame = -3
Query: 523 LILYAYQLSTALAYLESKR--FVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKAS 580
++ + Q ++AL Y+ + +HRD+ +N+ V+ V+LGD GL+R + + S
Sbjct: 417 IVCWLMQTASALNYMHTHTPVILHRDLKPQNIYVTEKGDVRLGDLGLARKLTGPADFATS 238
Query: 581 KGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIG------R 634
+ I +++PE ++ + + S SD+W G ++I G K +D +G +
Sbjct: 237 QVG-TIMYLSPEILSQQPYNSKSDIWSLGCVFYDI--------TGKKGSDEMGVMFLLVQ 85
Query: 635 IENGERLPMP 644
+ G +LP+P
Sbjct: 84 VMGGRKLPLP 55
>04591
Length = 1117
Score = 58.5 bits (140), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 43/158 (27%), Positives = 72/158 (45%), Gaps = 11/158 (6%)
Frame = -2
Query: 469 LQEALTMRQFDHPHIVKLIGVI---------TENPVWIIMELCTLGELRSFLQVRKYSLD 519
L+E ++Q +H ++V+L + ++ ++I E C +L L +
Sbjct: 1077 LREIKILQQLEHENVVQLQEICHTQAGPYNRYKSTFYLIFEYCDY-DLAGLLNNLRVKFS 901
Query: 520 LASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKA 579
LA QL L Y+ +K+ +HRDI A N+L++ + +KL DFGLSR S K
Sbjct: 900 LADKKNLMSQLLNGLFYIHTKQILHRDIKAANILLTRDGVLKLADFGLSRPWVKS---KR 730
Query: 580 SKGKLPIKWMAPESINF--RRFTSASDVWMFGVCMWEI 615
++ W P + R + D+W G M E+
Sbjct: 729 LTNRVVTLWYRPPELLLGEREYGPEIDMWGVGCIMAEM 616
>03240
Length = 1683
Score = 57.0 bits (136), Expect = 4e-08, Method: Compositional matrix adjust.
Identities = 63/263 (23%), Positives = 108/263 (41%), Gaps = 56/263 (21%)
Frame = -3
Query: 417 IQRERIELGRC-------IGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFL 469
I+ +R ++ +C +G G FG+V + + A+KT + SD ++ +
Sbjct: 1321 IRLKRAKMDKCMFEKIKTLGVGAFGEVS---LCRKNDTGMLYAMKTLRK--SDVLKRNQV 1157
Query: 470 QEALTMRQF----DHPHIVKLIGVITE-NPVWIIMELCTLGELRSFLQVRKYSLDLASLI 524
R D+ +VKL + N ++ +M+ G+L L +R LD
Sbjct: 1156 AHVKAERDILAEADNEWVVKLYYSFQDHNYLYFVMDYVPGGDLMGLL-IRMEILDEPLAR 980
Query: 525 LYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLS---RYMEDSTYYK--- 578
Y +L A+ + F+HRDI N+L+ N +KL DFGL R+ +S YY+
Sbjct: 979 FYVAELVQAIESVHRMGFIHRDIKPDNILIDRNGHIKLTDFGLCTGFRWTHNSKYYQRDG 800
Query: 579 --ASKGKLPIK-----------------------------------WMAPESIN-FRRFT 600
A + + +K ++APE ++ +T
Sbjct: 799 THARQDSMEVKCQLDEQCQCEILKPLERRRKREQRCLAHSLVGTPNYIAPEVLSRLGGYT 620
Query: 601 SASDVWMFGVCMWEILMHGVKPF 623
S D W GV ++E+L+ G PF
Sbjct: 619 SVCDWWSVGVILFEMLV-GHPPF 554
>21079
Length = 878
Score = 56.6 bits (135), Expect = 5e-08, Method: Compositional matrix adjust.
Identities = 34/128 (26%), Positives = 66/128 (51%), Gaps = 2/128 (1%)
Frame = +1
Query: 497 IIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSS 556
++ME GEL + + L + + Q+ + + Y+ ++ +H D+ NVL S
Sbjct: 55 LVMEFVGAGELFERVIRDDFVLTERDCVHFVRQICSGVGYMHTQSILHLDLKPENVLCVS 234
Query: 557 NDC--VKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWE 614
++ +K+ DFGL+R+ + + G P +++APE +N+ +D+W GV +
Sbjct: 235 DNSNQIKIIDFGLARFYKPGDSLQVLFGT-P-EFIAPEVVNYDEINFTTDMWSIGVICY- 405
Query: 615 ILMHGVKP 622
IL+ G+ P
Sbjct: 406 ILLSGLSP 429
>01707
Length = 757
Score = 55.8 bits (133), Expect = 8e-08, Method: Compositional matrix adjust.
Identities = 53/199 (26%), Positives = 90/199 (45%), Gaps = 10/199 (5%)
Frame = +1
Query: 428 IGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKF-LQEALTMRQFDHPHIVKL 486
IGEG +G V + + + VAIK D + +K ++E ++Q HP++V+L
Sbjct: 88 IGEGSYGVVFK---CRNKETSQLVAIKKFVESEDDPLIKKIAMREIRMLKQLKHPNLVRL 258
Query: 487 IGVITENP----VWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRF 542
I V V+ ++ L EL + R + I+Y Q A+ +
Sbjct: 259 IEVFRRKKRLHLVFDYVDHTLLNELDRY--PRGLPEPMVKRIIY--QTLLAVNFCHQYNT 426
Query: 543 VHRDIAARNVLVSSNDCVKLGDFGLSRYM----EDSTYYKASKGKLPIKWMAPE-SINFR 597
+HRD+ N+L++ VKL DFG +R + ++ T Y A++ + APE +
Sbjct: 427 IHRDVKPENILITRQGQVKLCDFGFARILTGPGDEYTDYVATRW-----YRAPELLVGDT 591
Query: 598 RFTSASDVWMFGVCMWEIL 616
++ DVW G E+L
Sbjct: 592 QYGPPVDVWAIGCVFAELL 648
>18484
Length = 635
Score = 55.5 bits (132), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 28/113 (24%), Positives = 59/113 (52%)
Frame = +1
Query: 525 LYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKL 584
YA +++ L +L + ++RD+ NV++ S +K+ DFG+ + +
Sbjct: 55 FYAAEIAVGLFFLHDQGIIYRDLKLDNVMLDSEGHIKIADFGMCKEGMTGDATTRTFCGT 234
Query: 585 PIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIEN 637
P ++APE + ++ ++ + D W +GV ++E+L G PF G +++ I +
Sbjct: 235 P-DYIAPEIVLYQPYSKSVDWWAYGVLLFEMLA-GQPPFDGEDEDELFSSITD 387
>07836
Length = 1478
Score = 54.3 bits (129), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 65/260 (25%), Positives = 112/260 (43%), Gaps = 43/260 (16%)
Frame = -1
Query: 465 REKFLQEALTMRQFDHPHIVKLI-----GVITENPVWIIMELCTLGELRSFLQVRKYSLD 519
RE L + + +R H +I+ I G + +++I + G L +L R LD
Sbjct: 1424 RETELYQTVLLR---HENILGFIAADIKGTGSWTQLFLITDYHENGSLHDYLLSR--VLD 1260
Query: 520 LASLILYAYQLSTALAYLESKRF--------VHRDIAARNVLVSSNDCVKLGDFGLS-RY 570
+ ++ A+ LA+L + F HRDI ++N+LV N + D GL+ RY
Sbjct: 1259 SSEMLALAHSAICGLAHLHIEIFGTRGKPAIAHRDIKSKNILVKKNGTCCIADLGLAVRY 1080
Query: 571 MEDSTYYKASKG--KLPIKWMAPESI-------NFRRFTSASDVWMFGVCMWEI----LM 617
+ +S + + ++MAPE + NF F A D++ FG+ MWEI ++
Sbjct: 1079 ISESNEVDVAPNPRQGTKRYMAPEVLEMLLNVKNFDAFKQA-DMYAFGLVMWEIARCCVI 903
Query: 618 HGVK-----PFQGVKNND--------VIGRIENGERLPMPPNCPP---TLYSLMTKCWAY 661
GV PF +D V+ + +P+ P + +M +CW+
Sbjct: 902 GGVAEEYQVPFYNCLPHDPSFEDVRLVVSVDKVRPDIPLRWQEDPIMKVMVKVMCECWSG 723
Query: 662 DPSRRPRFTELKAQLSTILE 681
+P+ R +K L + E
Sbjct: 722 NPAARLTALRVKKTLGKLSE 663
>01966
Length = 1735
Score = 53.9 bits (128), Expect = 4e-07, Method: Compositional matrix adjust.
Identities = 30/113 (26%), Positives = 62/113 (54%), Gaps = 3/113 (2%)
Frame = -1
Query: 460 TSDSVREKFLQEALTMRQFDHPHIVKLIGVITENP-VWIIMELCTLGELRSFLQV--RKY 516
+ D V ++E +R+ H +IV L VI E+ ++++ E ++ +L+ ++
Sbjct: 1597 SEDGVPSSAIREIAMLRELRHTNIVCLEDVIMEDERLFLVFEFLSM-DLKMYIDKFPEGV 1421
Query: 517 SLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSR 569
LD + Y +Q+ T + + +R VHRD+ +N+L++ +K+ DFG++R
Sbjct: 1420 VLDRRLVKSYVFQIVTGINFCHQRRIVHRDLKPQNLLINHTGAIKIADFGMAR 1262
>26711
Length = 405
Score = 50.8 bits (120), Expect = 3e-06, Method: Composition-based stats.
Identities = 32/102 (31%), Positives = 58/102 (56%), Gaps = 5/102 (4%)
Frame = -2
Query: 529 QLSTALAYLESKRFVHRDIAARNVLVSSN--DCVKLGDFGLSRYM---EDSTYYKASKGK 583
Q+ L ++ ++ VH D+ N+L+S + D V+L DFGL+R + +++ + G
Sbjct: 392 QVLDILQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARKLYPPQETFLNHGTPG- 216
Query: 584 LPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQG 625
+ +PE+++ + ++ASDVW GV + IL+ G PFQ
Sbjct: 215 ----FTSPEALDVKPISTASDVWGVGVLAY-ILLSGQSPFQA 105
>15910
Length = 1361
Score = 50.8 bits (120), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 34/107 (31%), Positives = 55/107 (51%), Gaps = 3/107 (2%)
Frame = +2
Query: 536 YLESKRFVHRDIAARNVL---VSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPE 592
Y+ + VHRD+ N+L ++ + +KL DFGLSR +E G P + APE
Sbjct: 509 YIHANGVVHRDLKPENLLYECMTDDSKLKLADFGLSRIIEPEVQMSTVCGT-P-GYCAPE 682
Query: 593 SINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGE 639
+ ++T + D+W GV + IL+ G +PF ++ +I GE
Sbjct: 683 VLKGDKYTPSVDMWSVGVIAY-ILLCGYEPFFAENEFEMYRKIIKGE 820
>12672
Length = 773
Score = 48.9 bits (115), Expect = 9e-06, Method: Compositional matrix adjust.
Identities = 38/162 (23%), Positives = 69/162 (42%), Gaps = 16/162 (9%)
Frame = +3
Query: 531 STALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGL---SRYMEDSTYYKASKGKLPIK 587
++ + YL VHRDI N+L+ S K+GDF + E T AS
Sbjct: 21 ASGIQYLNDNGHVHRDIKTANILLDSEYTAKVGDFATVVSAPSGEGKTVQNASVVIGTAA 200
Query: 588 WMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPF----QGVKNNDVIGRIENGERL-- 641
++APE+I+F ++ D + FGV + E++ V + ++ ++ +E E +
Sbjct: 201 YLAPEAIHF-DVSTKLDSYSFGVVLLEVITGLVAQDYSREERTLSSHIMENVEEPEEIHD 377
Query: 642 -------PMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQL 676
P LY + +C +RP +++ +L
Sbjct: 378 FVDQSAGTWPDGAVDKLYDISMRCLNLSKKQRPNVKDIRPEL 503
>25550
Length = 941
Score = 48.9 bits (115), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 25/76 (32%), Positives = 37/76 (48%), Gaps = 1/76 (1%)
Frame = +3
Query: 608 FGVC-MWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRR 666
G C +W++ + GV +V +E G R+ P P +Y LM KCW +DP R
Sbjct: 12 MGACDIWDVX------YPGVDLTEVYHLLERGYRMERPQGTPADVYILMLKCWQWDPKER 173
Query: 667 PRFTELKAQLSTILEE 682
P F E+ L + E+
Sbjct: 174 PTFKEIHYLLENMFEK 221
>32264
Length = 287
Score = 48.5 bits (114), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 21/48 (43%), Positives = 28/48 (58%)
Frame = +1
Query: 635 IENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEE 682
IE+G RL P P ++Y LM +CW Y P +RP F EL L I+ +
Sbjct: 1 IEDGYRLQQNPQTPDSVYKLMLRCWEYVPEKRPHFKELYTSLKDIVRK 144
>21433
Length = 590
Score = 48.1 bits (113), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 30/98 (30%), Positives = 49/98 (50%)
Frame = +2
Query: 526 YAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLP 585
Y YQLS+AL Y ++ +HRDI N+L+ +K+ DFG S + S + +
Sbjct: 182 YIYQLSSALEYCHYRKVIHRDIKPENLLLGLKGDLKIADFGWSVHAPSS---RRTTMCGT 352
Query: 586 IKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPF 623
+ ++ PE + + D+W GV +E L+ G P
Sbjct: 353 LDYLPPEMVEGKTHDENVDLWSLGVLCYEFLV-GTPPL 463
>28157
Length = 400
Score = 46.2 bits (108), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 31/112 (27%), Positives = 54/112 (48%), Gaps = 6/112 (5%)
Frame = +3
Query: 461 SDSVREKFLQEALTMRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVR--KYSL 518
S+ ++ F+QE + + HP+IV L G ++PV ++ME G L + L +
Sbjct: 30 SEQEKKSFMQELKQLSRVSHPNIVCLYGACRDHPVCLVMEYAEGGSLYNVLHGSGPQPQY 209
Query: 519 DLASLILYAYQLSTALAYLES---KRFVHRDIAARN-VLVSSNDCVKLGDFG 566
A + + Q + + YL K +HRD+ N +L+ +K+ DFG
Sbjct: 210 TAAHAMNWLLQCALGVEYLHGMKPKALIHRDLKPPNLLLIQCGTKLKICDFG 365
>26560
Length = 398
Score = 43.9 bits (102), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 32/113 (28%), Positives = 58/113 (51%), Gaps = 1/113 (0%)
Frame = -1
Query: 525 LYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKL 584
YA ++ L ++ S+ V+RD+ N+L+ N V++ D GL+ D + +
Sbjct: 344 FYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGLA---CDFSKKRPHASVG 174
Query: 585 PIKWMAPESI-NFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIE 636
+MAPE + + + S++D + FG CM L+ G PF+ ++N RI+
Sbjct: 173 THGYMAPEVLMKGQSYDSSADWFSFG-CMLYKLLKGHSPFR--QHNQGQARID 24
>04138
Length = 800
Score = 43.5 bits (101), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 24/85 (28%), Positives = 42/85 (49%), Gaps = 3/85 (3%)
Frame = +1
Query: 534 LAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSR-YMEDSTYYKASKGKLPIKWMAPE 592
L Y+ + +HRD+ A N+L++ +KL DFGL+R + + ++ W P
Sbjct: 52 LYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRPP 231
Query: 593 SINF--RRFTSASDVWMFGVCMWEI 615
+ R +++A D W G M E+
Sbjct: 232 ELLLGDRNYSTAIDQWGAGCIMAEM 306
>01392
Length = 1806
Score = 42.4 bits (98), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 37/123 (30%), Positives = 59/123 (47%), Gaps = 12/123 (9%)
Frame = -1
Query: 521 ASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSND---CVKLGDFGLSRYME-DSTY 576
ASL++ ++ AL +L SK HRD+ N+L D VK+ DF L+ + D
Sbjct: 1785 ASLVVR--HIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGISCDGDG 1612
Query: 577 YKASKGKLPI---KWMAPESINFRRFTSAS-----DVWMFGVCMWEILMHGVKPFQGVKN 628
K + P+ ++MAPE ++ S S D+W G+ ++ I++ G PF G
Sbjct: 1611 TKTPELLTPVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILY-IMLCGYPPFYGQCG 1435
Query: 629 NDV 631
D
Sbjct: 1434 EDC 1426
>12786
Length = 460
Score = 41.2 bits (95), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 39/143 (27%), Positives = 69/143 (48%), Gaps = 23/143 (16%)
Frame = -3
Query: 517 SLDLASLILYAYQLSTALAYLESKRFVHRDIAARN-VLVSSNDCVKLGDFGLSRYMED-- 573
LD + Y ++ A+ L ++ +H D+ N +LV+ N +KL DFG++ ++
Sbjct: 422 GLDRMMIKFYWREMLRAVKALHNEGVIHSDLKPANFMLVAGN--LKLIDFGIANTLQQDK 249
Query: 574 STYYKASKGKLPIKWMAPESINFRRFTSA--------------------SDVWMFGVCMW 613
++ K S+ P +M+PE+I SA SDVW G C+
Sbjct: 248 TSVLKDSRVGTP-SYMSPEAIMAACDDSADDSMEEDGHRTKPKYKVGVRSDVWSLG-CIL 75
Query: 614 EILMHGVKPFQGVKNNDVIGRIE 636
+++G PFQ +KNN +G+++
Sbjct: 74 YNMVYGRTPFQHIKNN--MGKLQ 12
>07933
Length = 728
Score = 40.0 bits (92), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 15/39 (38%), Positives = 26/39 (66%)
Frame = +3
Query: 644 PPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEE 682
P CP LY++M +CW+ +PS RP F +L+ + ++E+
Sbjct: 3 PNYCPNLLYNIMMQCWSAEPSARPTFHKLEQDIVAMVEQ 119
>03508
Length = 1463
Score = 40.0 bits (92), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 26/100 (26%), Positives = 48/100 (48%), Gaps = 2/100 (2%)
Frame = +1
Query: 525 LYAYQLSTALAYLESKRFVHRDIAARNVLVS-SNDCVKLGDFGLSRYMEDSTYYKASKGK 583
Y Y+L AL + S +HRD+ NV++ N ++L D+GL+ + Y
Sbjct: 883 FYLYELMKALDFCHSMGIMHRDVKPHNVMIDHENKKLRLIDWGLAEFYHPGMEYNVRVAS 1062
Query: 584 LPIKWMAPE-SINFRRFTSASDVWMFGVCMWEILMHGVKP 622
K PE ++++ + + D+W G CM+ ++ +P
Sbjct: 1063RYFK--GPELLLDYQMYDYSLDMWSLG-CMFASMIFRKEP 1173
>37602
Length = 804
Score = 38.5 bits (88), Expect = 0.014, Method: Compositional matrix adjust.
Identities = 22/71 (30%), Positives = 32/71 (45%)
Frame = -1
Query: 495 VWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLV 554
+WI ME C G ++ V L + + L YL + +HRDI N+L+
Sbjct: 294 LWIAMEYCGGGSMQDIYHVTG-PLTEPQIAFVCRETLKGLHYLHRRGKMHRDIKGANILL 118
Query: 555 SSNDCVKLGDF 565
+ VKL DF
Sbjct: 117 TEEGDVKLADF 85
>38046
Length = 446
Score = 38.1 bits (87), Expect = 0.018, Method: Composition-based stats.
Identities = 14/32 (43%), Positives = 24/32 (75%)
Frame = -1
Query: 530 LSTALAYLESKRFVHRDIAARNVLVSSNDCVK 561
++ A+AY+E + F+HR++ RN+LV N+ VK
Sbjct: 98 IADAMAYMEKENFIHRNLGDRNILVGPNNRVK 3
>18481
Length = 437
Score = 37.4 bits (85), Expect = 0.030, Method: Composition-based stats.
Identities = 26/82 (31%), Positives = 44/82 (53%), Gaps = 4/82 (4%)
Frame = -1
Query: 497 IIMELCTLG-ELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVS 555
++MEL LG L + K L ++++ + QL + L ++ K F+HRD+ N L+
Sbjct: 266 LVMEL--LGPSLEELFVICKRRFTLKTILMVSDQLLSRLEFIHQKCFIHRDLKPDNFLMG 93
Query: 556 -SNDCVKLG--DFGLSRYMEDS 574
C +L DFGLS+ +D+
Sbjct: 92 LGRHCHRLYIIDFGLSKRYKDT 27
>11185
Length = 473
Score = 37.4 bits (85), Expect = 0.032, Method: Compositional matrix adjust.
Identities = 37/168 (22%), Positives = 62/168 (36%), Gaps = 21/168 (12%)
Frame = +1
Query: 526 YAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRY----MEDSTYYKASK 581
+ L T L Y+ S + D+ VL+ ++ +K DFGLS+ +E+ + A
Sbjct: 16 FGIHLVTGLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEA 195
Query: 582 G-------------KLPIK----WMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQ 624
G ++P +MAPE + SD+W G +E+
Sbjct: 196 GDQWNIQSAEEMMKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMF-------- 351
Query: 625 GVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTEL 672
+G RL P+ P +L+ D +RR + L
Sbjct: 352 ------------SGSRLSAKPS--PEFLNLLESLLQKDSTRRLSWASL 453
>02638
Length = 1490
Score = 36.2 bits (82), Expect = 0.063, Method: Composition-based stats.
Identities = 28/92 (30%), Positives = 42/92 (45%), Gaps = 5/92 (5%)
Frame = +1
Query: 586 IKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKP---FQGVKNN-DVIGRIENG-ER 640
I +MAPE + + A DVW G M E M +P + N+ +I +I + +
Sbjct: 28 IAFMAPEVLRGESYGRACDVWSVGCVMIE--MCTCRPPWNSHDISNHLALIFKIASSVDP 201
Query: 641 LPMPPNCPPTLYSLMTKCWAYDPSRRPRFTEL 672
P+P N P + LM +C D RP +L
Sbjct: 202 PPIPENMSPPVRDLMLRCLEQDSDFRPSAKDL 297
>00486
Length = 797
Score = 35.0 bits (79), Expect = 0.18, Method: Compositional matrix adjust.
Identities = 24/81 (29%), Positives = 36/81 (44%)
Frame = -2
Query: 586 IKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPP 645
I++MAPE + A D W G M+++L G PF I +I G +L +PP
Sbjct: 766 IEYMAPEILTRTGHGKAVDWWSLGALMYDMLT-GSPPFTAENRKKTIDKILKG-KLNLPP 593
Query: 646 NCPPTLYSLMTKCWAYDPSRR 666
L+ K +P+ R
Sbjct: 592 YLTNEARGLIKKLLRKNPAER 530
>26009
Length = 886
Score = 34.7 bits (78), Expect = 0.21, Method: Compositional matrix adjust.
Identities = 15/30 (50%), Positives = 21/30 (70%)
Frame = +3
Query: 529 QLSTALAYLESKRFVHRDIAARNVLVSSND 558
QL +AL ++ SK+ VHRDI NVL+ + D
Sbjct: 735 QLVSALDFMHSKQLVHRDIKPENVLILTPD 824
>16708
Length = 1397
Score = 34.3 bits (77), Expect = 0.29, Method: Compositional matrix adjust.
Identities = 17/49 (34%), Positives = 27/49 (55%)
Frame = -1
Query: 521 ASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSR 569
A + A Q AL ++ VH D+ A NVLV ++ KL D+G+++
Sbjct: 1094 AMVCCIAGQXVCALEHIHELGVVHMDVKADNVLVDAHGNCKLTDYGIAQ 948
>15741
Length = 402
Score = 33.9 bits (76), Expect = 0.35, Method: Composition-based stats.
Identities = 15/44 (34%), Positives = 24/44 (54%)
Frame = -3
Query: 510 FLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVL 553
FL L +A ++ +A++ + + VHRD+AARNVL
Sbjct: 133 FLTSTANDLTARDFFSFALHVARGMAHVANNKIVHRDVAARNVL 2
>27287
Length = 514
Score = 33.9 bits (76), Expect = 0.36, Method: Compositional matrix adjust.
Identities = 13/37 (35%), Positives = 20/37 (54%)
Frame = -2
Query: 644 PPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTIL 680
PP ++ +M CW DP+ RP F+ L +L +L
Sbjct: 504 PPYASSEMFGIMHSCWQEDPNDRPSFSRLVQELDKML 394
>27405
Length = 532
Score = 33.5 bits (75), Expect = 0.40, Method: Compositional matrix adjust.
Identities = 14/44 (31%), Positives = 26/44 (59%)
Frame = -3
Query: 525 LYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLS 568
YA ++ L ++ S+ V+RD+ N+L+ N V++ D GL+
Sbjct: 242 FYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGLA 111
>21210
Length = 518
Score = 33.1 bits (74), Expect = 0.63, Method: Compositional matrix adjust.
Identities = 30/104 (28%), Positives = 47/104 (45%), Gaps = 7/104 (6%)
Frame = +3
Query: 588 WMAPESINFRR----FTSASDVWMFGVCMWEILMHGVKPFQG-VKNNDVIGRIENGER-- 640
+MAPE I+ R + SDVW G+ + E L G P++ V D + ++ G
Sbjct: 18 YMAPERIDPRASSHGYDVRSDVWSLGITLME-LATGRFPYRKWVSIFDQLQQVVRGVAPC 194
Query: 641 LPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEK 684
LP + + KC D +RP++ +L A L EE+
Sbjct: 195 LPHDGAFSHDFVNFVNKCLTKDEKQRPKYNKLLAHPFVRLYEEQ 326
>25019
Length = 730
Score = 31.6 bits (70), Expect = 1.8, Method: Composition-based stats.
Identities = 22/62 (35%), Positives = 29/62 (46%)
Frame = +3
Query: 548 AARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWM 607
AA NVL+ + VKL DFGL + T + I++MAPE + A D W
Sbjct: 255 AAENVLLDKDGHVKLTDFGLCKEAITGTRVTHTFCG-TIEYMAPEILTRTGHGKAVDWWS 431
Query: 608 FG 609
G
Sbjct: 432 LG 437
>32359
Length = 928
Score = 30.4 bits (67), Expect = 3.5, Method: Compositional matrix adjust.
Identities = 35/128 (27%), Positives = 60/128 (46%), Gaps = 9/128 (7%)
Frame = -1
Query: 425 GRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIV 484
+ IG G FG V+Q + + + VAIK K + + LQ MR+ +H +IV
Sbjct: 415 AKVIGNGSFGVVYQAKLV---DTSELVAIK--KVLQDKRFKNRELQ---IMRKLEHQNIV 260
Query: 485 KLIGVI-----TENPVWI--IMELC--TLGELRSFLQVRKYSLDLASLILYAYQLSTALA 535
KL ++ V++ ++E T+ + K ++ + + LY YQL +LA
Sbjct: 259 KLKFFFYSSGEKKDEVFLNLVLEYVPETVYRVARHYSKSKQTIPILYIKLYMYQLFRSLA 80
Query: 536 YLESKRFV 543
Y+ S+ V
Sbjct: 79 YIHSQACV 56
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000378647 | hsapiens_gene_ensembl | Focal adhesion
kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK) (Protein- tyrosine kinase
2). [Source:Uniprot/SWISSPROT;Acc:Q05397]
(1007 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
06405 221 2e-57
21808 199 4e-51
11780 121 2e-44
09007 175 7e-44
04852 162 6e-40
14116 144 2e-34
07291 137 2e-32
17300 124 5e-30
20640 125 8e-29
07940 118 1e-26
08294 117 2e-26
18996 110 2e-24
14477 108 1e-23
17253 97 4e-20
18921 96 9e-20
22005 96 9e-20
17637 90 5e-18
13305 87 3e-17
01718 87 3e-17
00300 86 5e-17
19301 82 8e-16
12721 78 2e-14
14420 75 2e-13
13592 74 4e-13
27546 69 7e-12
30755 69 9e-12
00715 68 2e-11
13066 67 4e-11
31885 67 4e-11
07833 66 7e-11
01060 66 9e-11
09606 65 1e-10
14126 63 7e-10
19094 62 1e-09
13212 62 2e-09
29581 60 5e-09
01756 59 7e-09
19761 59 1e-08
04591 59 1e-08
03240 57 4e-08
21079 57 5e-08
01707 55 1e-07
18484 55 1e-07
07836 55 2e-07
01966 54 3e-07
26711 51 3e-06
15910 51 3e-06
25550 49 8e-06
12672 49 9e-06
32264 49 1e-05
21433 48 2e-05
28157 46 6e-05
26560 44 3e-04
04138 44 4e-04
01392 42 0.001
12786 41 0.002
07933 40 0.005
03508 40 0.005
37602 39 0.014
38046 38 0.017
18481 38 0.026
11185 37 0.031
00486 35 0.16
26009 35 0.21
16708 34 0.28
27287 34 0.31
15741 34 0.34
27405 34 0.34
02638 33 0.50
21210 33 0.55
25019 32 1.8
32359 30 3.5
>06405
Length = 1965
Score = 221 bits (562), Expect = 2e-57, Method: Compositional matrix adjust.
Identities = 108/270 (40%), Positives = 164/270 (60%), Gaps = 2/270 (0%)
Frame = +1
Query: 367 YEIQRERIELGRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEALT 426
+EI+R I + +G GQ+GDV++ ++ VA+KT K T FL+EA
Sbjct: 244 WEIERTEIAMKHRLGGGQYGDVYEAMWKRYNK---IVAVKTLKEDTM--ALNDFLEEAAI 408
Query: 427 MRQFDHPHIVKLIGVIT-ENPVWIIMELCTLGELRSFLQVRKYSLDLASLILY-AYQLST 484
M++ HP++V+L+GV T E P +I+ E G L +L+ + + ++Y A Q+++
Sbjct: 409 MKEMKHPNLVQLLGVCTREPPFYIVTEFMPHGNLLDYLRSSTREENGPTALMYMATQIAS 588
Query: 485 ALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPE 544
+AYLE+K F+HRD+AARN LV+ ++ VK+ DFGL+R M+D TY K PIKW APE
Sbjct: 589 GMAYLETKNFIHRDLAARNCLVADSNMVKVADFGLARLMKDDTYTAHIGAKFPIKWTAPE 768
Query: 545 SINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLY 604
+ F RF++ SD+W FGV +WE+ +G+ P+ GV+ +V +E G R+ PP P +Y
Sbjct: 769 GLAFNRFSTRSDIWAFGVLLWELATYGMSPYPGVELTEVYHLLERGYRMERPPGTPADVY 948
Query: 605 SLMTKCWAYDPSRRPRFTELKAQLSTILEE 634
LM KCW +DP RP F E+ L + E+
Sbjct: 949 ILMLKCWQWDPKDRPTFKEIHFLLENMFEK 1038
>21808
Length = 1011
Score = 199 bits (506), Expect = 4e-51, Method: Compositional matrix adjust.
Identities = 98/236 (41%), Positives = 144/236 (61%), Gaps = 1/236 (0%)
Frame = +1
Query: 398 NPALAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITEN-PVWIIMELCTL 456
N VAIKT K+ T D + FL EA M++ HP +++L V T++ P++II EL
Sbjct: 13 NNTTPVAIKTLKSGTMDP--KDFLAEAQIMKKLRHPKLIQLYAVCTQDDPIFIITELMKN 186
Query: 457 GELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGD 516
G L FLQ + L L +LI Q++ +AYLES+ ++HRD+AARN+LVS N+ VK+ D
Sbjct: 187 GSLLEFLQGKGRVLKLPALIDIGAQIACGMAYLESQNYIHRDLAARNILVSDNNTVKIAD 366
Query: 517 FGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQ 576
FGL+R +++ Y + PIKW APE+ N+ RFT SDVW FG+ + E + +G P+
Sbjct: 367 FGLARVIKEDEYEARVGARFPIKWTAPEAANYNRFTIKSDVWSFGILLTETVTYGRVPYP 546
Query: 577 GVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTIL 632
G+ N +V+ ++E+G R+P PP CP LY +M +CW + RP + IL
Sbjct: 547 GMTNAEVLHQVEHGYRMPCPPGCPKPLYDIMLECWRKEEMERPHLRNPAMEAGGIL 714
>11780
Length = 1713
Score = 121 bits (303), Expect(2) = 2e-44, Method: Compositional matrix adjust.
Identities = 69/179 (38%), Positives = 102/179 (56%), Gaps = 1/179 (0%)
Frame = +3
Query: 369 IQRERIELGRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTMR 428
I + +E+G IG+G FGDV++G+Y VAIK K+ D + FLQEA M
Sbjct: 588 IAXQDLEIGEAIGKGDFGDVYKGMYRGQ-----PVAIKQLKD--KDRGEQSFLQEASVMT 746
Query: 429 QFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVRKYS-LDLASLILYAYQLSTALA 487
H ++V+LIGV+ ++++ E G L +L+ R S + I +A A+
Sbjct: 747 SLRHDNLVRLIGVVLGETIFLVTEFMGKGNLVEYLRSRGRSVITKKDQINFATDTCAAME 926
Query: 488 YLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESI 546
YLESKR VHRD+AARNVLV + K+ DFGL+++ + + + K PIKW APE++
Sbjct: 927 YLESKRLVHRDLAARNVLVHDDGKAKVSDFGLAKFGD----FSQTSVKFPIKWTAPEAL 1091
Score = 77.8 bits (190), Expect(2) = 2e-44, Method: Compositional matrix adjust.
Identities = 33/81 (40%), Positives = 49/81 (60%)
Frame = +1
Query: 550 RFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTK 609
+FTS SD+W FG+ +WEI G P+ + DV+ +E G R+ P CPP +YS+M +
Sbjct: 1102 KFTSKSDMWSFGILLWEIYSFGRVPYPRIPLTDVVMHVERGYRMEAPEGCPPEIYSIMKQ 1281
Query: 610 CWAYDPSRRPRFTELKAQLST 630
W DP+ RP F + A+L+
Sbjct: 1282 AWELDPNERPTFKSVLARLNN 1344
>09007
Length = 1440
Score = 175 bits (444), Expect = 7e-44, Method: Compositional matrix adjust.
Identities = 94/274 (34%), Positives = 146/274 (53%), Gaps = 11/274 (4%)
Frame = -1
Query: 369 IQRERIELGRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTMR 428
I ++ + L + +G+G FG V Q I+ + + VA+K ++FL+E M+
Sbjct: 888 ISKDCVALSKSLGQGHFGTVRQAIWTAESGEKVQVAVKCLSKDKIHKDGQEFLKETAIMQ 709
Query: 429 QFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVRK-----YSLDLASLILYAYQLS 483
DH +IV++ GV+ +N IM + L +RS L+ K + L ++ Q+
Sbjct: 708 MLDHENIVRVYGVVMDNGA-DIMLVTELAPMRSLLECVKEVSARVDFSVPRLCDFSQQVC 532
Query: 484 TALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKL----PIK 539
++YLESKR VHRD+AARN+L+ S VK+ D G+S + Y S+ + +
Sbjct: 531 DGMSYLESKRLVHRDLAARNILLFSKSKVKISDVGVSGALGAGKEYYQSQQTIHLQNAVA 352
Query: 540 WMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIE--NGERLPMPP 597
W APES F+SASDVW FGV +WE HG +P+ G+ ++ ++ +RL P
Sbjct: 351 WCAPESFRNLCFSSASDVWAFGVLLWEFFTHGFQPWAGLNGQQIMEAVDAPQSQRLEQPD 172
Query: 598 NCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTI 631
CP Y++M KCW +P RRP F++L L I
Sbjct: 171 LCPKEYYAVMLKCWEQEPQRRPTFSQLFLTLPQI 70
>04852
Length = 1462
Score = 162 bits (410), Expect = 6e-40, Method: Compositional matrix adjust.
Identities = 88/263 (33%), Positives = 141/263 (53%), Gaps = 30/263 (11%)
Frame = +1
Query: 400 ALAVAIKTCKNCTSDSVREKFLQEALTMRQF----DHPHIVKLIGVITEN-PVWIIMELC 454
A VA+K ++ + + F+QE M+ H +IV +G T+ P+W+I+E
Sbjct: 19 ASTVAVKMLRDIVTAVEEQDFVQELQVMKAVKKMGSHINIVNFLGCCTQGGPLWVIVEFA 198
Query: 455 TLGELRSFLQ-----VRKYS-------------------LDLASLILYAYQLSTALAYLE 490
G LR FL+ + Y + +L+ YA+Q++ + +L
Sbjct: 199 KNGNLRDFLESCRDGINGYGKFVSPQDPGWYTKTPGGHVIRRKNLLSYAFQIARGMEFLA 378
Query: 491 SKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRR 550
S++ +HRD+AARNVLV+ +K+ DFGLSR Y K S G+LP+KWMAPE++ R
Sbjct: 379 SRKCIHRDLAARNVLVTEEHVLKIADFGLSR--TGDYYKKRSGGRLPVKWMAPEALFDMR 552
Query: 551 FTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGR-IENGERLPMPPNCPPTLYSLMTK 609
+T+ SDVW FGV +WEI G P+ + N ++ + +++ R+P P LY++M +
Sbjct: 553 YTTKSDVWSFGVVLWEIFSLGGMPYASIPNEELYSKLLDDAYRMPRPELASGNLYAIMER 732
Query: 610 CWAYDPSRRPRFTELKAQLSTIL 632
CW PS RP F++L + +L
Sbjct: 733 CWLNRPSDRPEFSQLVGHIDRLL 801
>14116
Length = 1017
Score = 144 bits (363), Expect = 2e-34, Method: Compositional matrix adjust.
Identities = 76/210 (36%), Positives = 124/210 (59%), Gaps = 7/210 (3%)
Frame = -1
Query: 369 IQRERIELGRCIGEGQFGDVHQGIYMSPENPA-LAVAIKTCKNCTSDSVR-EKFLQEALT 426
I RE + +G IG+G FG V +G PE + VA+KT N + + FLQEAL
Sbjct: 645 IDREFLTMGEEIGKGNFGCVKRGFLTLPEQKGDILVAVKTLHNNNPREIELQSFLQEALI 466
Query: 427 MRQFDHPHIVKLIGV---ITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLS 483
M+ F H +++ LIG+ + + P+ +++ G+L ++++ ++ + LI+Y ++
Sbjct: 465 MKDFHHSNVLTLIGICLNLDDMPL-VVLPFMKHGDLLTYIRDDQHQPTIKDLIMYGVDIA 289
Query: 484 TALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKA--SKGKLPIKWM 541
+ YL +FVHRD+AARN ++ + VK+ DFGL+R + + YY + K KLP+KWM
Sbjct: 288 RGMDYLAGLKFVHRDLAARNCMLDEDFHVKVADFGLARDIYEKEYYSSENKKAKLPVKWM 109
Query: 542 APESINFRRFTSASDVWMFGVCMWEILMHG 571
A ES+ + S +DVW +GV +WE+L G
Sbjct: 108 ALESLEKGNYDSKTDVWSYGVVLWELLTRG 19
>07291
Length = 833
Score = 137 bits (346), Expect = 2e-32, Method: Compositional matrix adjust.
Identities = 62/164 (37%), Positives = 101/164 (61%), Gaps = 2/164 (1%)
Frame = +1
Query: 470 LDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYY 529
L + L+ + Q++ +AYL+ + VHR++AARN +V+ + ++L D+G++ + +YY
Sbjct: 40 LTVVQLLDFGRQIADGMAYLQEVKVVHRNLAARNCIVTEDGRLQLSDYGVTGSLFPQSYY 219
Query: 530 KA--SKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRI 587
A S + +KWMAPE+I+ F+S SDVW FGV +WE+L G+ P+ V+N+ ++ +
Sbjct: 220 TADDSPARDLVKWMAPETIDNFHFSSKSDVWAFGVVLWELLTRGITPYPDVENSSLLPYL 399
Query: 588 ENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTI 631
+ G R+ P P +Y +MT CW P +RP F EL QL T
Sbjct: 400 KEGHRMKKPKQSPEPVYEMMTACWNESPEQRPDFAELNDQLKTF 531
>17300
Length = 480
Score = 124 bits (310), Expect(2) = 5e-30, Method: Compositional matrix adjust.
Identities = 56/117 (47%), Positives = 78/117 (66%), Gaps = 3/117 (2%)
Frame = +1
Query: 482 LSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTY---YKASKGKLPI 538
+S+ + L +VHRD+AARN+LV+ K+ DFGLSR +E T Y GK+P+
Sbjct: 1 ISSGMGXLADMGYVHRDLAARNILVNEILVCKVADFGLSREIESDTTEGAYTTKGGKIPV 180
Query: 539 KWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPM 595
+W APE+I +R+FTSASDVW FGV MWE++ +G +P+ N DVI +E G RLP+
Sbjct: 181 RWTAPEAIAYRKFTSASDVWSFGVVMWEVMSYGERPYWNWSNQDVIKAVEKGYRLPL 351
Score = 26.6 bits (57), Expect(2) = 5e-30, Method: Compositional matrix adjust.
Identities = 10/35 (28%), Positives = 18/35 (51%)
Frame = +2
Query: 598 NCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTIL 632
+CP L+ LM W + S RP+ + + L ++
Sbjct: 356 DCPEALHQLMLDAWQKERSHRPKMSMVVKTLDKLI 460
>20640
Length = 1492
Score = 125 bits (314), Expect = 8e-29, Method: Compositional matrix adjust.
Identities = 55/139 (39%), Positives = 85/139 (61%), Gaps = 1/139 (0%)
Frame = +1
Query: 494 FVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASK-GKLPIKWMAPESINFRRFT 552
+VHRD+A RN LV + VK+ DFGL+R + YY+ S+ +PI+WM E+I + +F+
Sbjct: 7 YVHRDLATRNCLVGHDLVVKISDFGLARSVHSVDYYRGSEHDAIPIRWMPLEAILYNKFS 186
Query: 553 SASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWA 612
+ SDVW FGV +WEI ++P+ G+ + +V+ ++ G+ L P PP +Y LM +CW
Sbjct: 187 TQSDVWSFGVVLWEIFAFALQPYYGLTHEEVVRFVKEGKVLACPERTPPPMYELMKQCWH 366
Query: 613 YDPSRRPRFTELKAQLSTI 631
P+ RP F L L +
Sbjct: 367 RRPATRPSFHTLHKTLENM 423
>07940
Length = 1336
Score = 118 bits (296), Expect = 1e-26, Method: Compositional matrix adjust.
Identities = 54/111 (48%), Positives = 77/111 (69%), Gaps = 1/111 (0%)
Frame = -3
Query: 475 LILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYY-KASK 533
LI YAYQ++ + YL SK+ +HRD+AARNVLV+ +K+ DFGL+R ++ YY K +
Sbjct: 341 LISYAYQVARGMEYLASKQCIHRDLAARNVLVAEEYVLKIADFGLTRNLQQFDYYRKTTD 162
Query: 534 GKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVI 584
G+LP+KWMAPE++ R++TS SDVW +GV +WEI G P+ V D+
Sbjct: 161 GRLPVKWMAPEALFDRKYTSKSDVWSYGVLLWEIFTLGGNPYPSVPVEDLF 9
Score = 55.5 bits (132), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 35/116 (30%), Positives = 60/116 (51%), Gaps = 4/116 (3%)
Frame = -3
Query: 356 IKSYCIDVARDYEIQRERIELGRCIGEGQFGDVHQGIYMS--PENPALAVAIKTCKNCTS 413
+ Y + + +E RER+ LG +GEG FG V +G M +N ++ VA+K K +
Sbjct: 890 VSEYDLPLDAKWEFPRERLVLGDRLGEGAFGLVMKGEAMGIFKDNNSVTVAVKMLKEDAT 711
Query: 414 DSVREKFLQEALTMRQFD-HPHIVKLIGVITE-NPVWIIMELCTLGELRSFLQVRK 467
D ++E M+ H +I+ L+G T+ +++I+E G LR FL+ +
Sbjct: 710 DREMMDLIREMEMMKVIGKHKNIINLLGCCTQRGALYVIVEFAPHGNLRDFLKSHR 543
>08294
Length = 1849
Score = 117 bits (293), Expect = 2e-26, Method: Compositional matrix adjust.
Identities = 67/209 (32%), Positives = 113/209 (54%), Gaps = 12/209 (5%)
Frame = +2
Query: 433 PHIVKLIGVITE-NPVWIIMELCTLGELRSFL-----------QVRKYSLDLASLILYAY 480
P+IV +GV E P ++I E C G+L+ FL R +L L+ +
Sbjct: 887 PNIVHFMGVCREAEPHFLITEYCDWGDLKQFLLATRNDNGRGRGTRVPALALSQKLGMGQ 1066
Query: 481 QLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKW 540
Q++ + L ++ VH D+AARNVL++S +K+ LS + S YY + +P++W
Sbjct: 1067 QVAAGMEALSNQGLVHGDLAARNVLLTSRMQLKVARPALSGDVYASEYYPLHQRLVPLRW 1246
Query: 541 MAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCP 600
+ PE + T+ DVW FGV +WE+L P++ + + +V+ +++ + P+ P
Sbjct: 1247 LPPEGVLEDSATTCGDVWAFGVFLWEVLQLADLPYRLMSDEEVLRSLQHSQAALDSPDAP 1426
Query: 601 PTLYSLMTKCWAYDPSRRPRFTELKAQLS 629
P L SL+ +C A PS+RP F+E+ + LS
Sbjct: 1427 PALLSLLQRCTAQQPSQRPPFSEICSVLS 1513
>18996
Length = 491
Score = 110 bits (276), Expect = 2e-24, Method: Compositional matrix adjust.
Identities = 56/136 (41%), Positives = 82/136 (60%), Gaps = 6/136 (4%)
Frame = +2
Query: 495 VHRDIAARNVLVSSNDCVKLGDFGLSRYME-DSTYYKASKGKLPIKWMAPESINFRRFTS 553
+HRD+AARN+LV + CVK+ DFGL+++ D YY S+ +PIKW +PE+I +F+S
Sbjct: 2 IHRDLAARNILVDRS-CVKISDFGLAQFANADGYYYGISQRDIPIKWYSPEAIETCKFSS 178
Query: 554 ASDVWMFGVCMWEILMHG----VKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYS-LMT 608
SDVW +GV ++E+ G + P + + + R+ GERLP P C +YS LM
Sbjct: 179 YSDVWSYGVTLFEMFSRGEIPNLLPGHDLTQEEFLNRLRKGERLPKPELCSDFVYSELMR 358
Query: 609 KCWAYDPSRRPRFTEL 624
CW P RP F ++
Sbjct: 359 PCWHEMPKSRPTFHQI 406
>14477
Length = 493
Score = 108 bits (270), Expect = 1e-23, Method: Compositional matrix adjust.
Identities = 59/157 (37%), Positives = 96/157 (61%), Gaps = 2/157 (1%)
Frame = -1
Query: 380 IGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSD-SVREKFLQEALTMRQFDHPHIVKL 438
+G G FG V +G+ ++ + VAIK KN D SV+ + ++EA M++ DH HIV+L
Sbjct: 466 LGAGNFGSVMKGVC-RLDDREIPVAIKVLKNADLDPSVQSELIKEAEVMKKMDHMHIVRL 290
Query: 439 IGVITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRD 498
IG+ + +++EL LG L FL K+ L L +++ +Q+S + YLE+ +FVHRD
Sbjct: 289 IGLCEGETMMLVLELAKLGPLNKFLPKNKH-LPLWNILELMWQVSQGMEYLEANKFVHRD 113
Query: 499 IAARNVLVSSNDCVKLGDFGLSRYM-EDSTYYKASKG 534
+AARN+L+ K+ DFG+S+ + ++ YY A +
Sbjct: 112 LAARNILLCDEHFAKISDFGMSKTLSRENNYYMAQEA 2
>17253
Length = 483
Score = 96.7 bits (239), Expect = 4e-20, Method: Composition-based stats.
Identities = 55/153 (35%), Positives = 88/153 (57%), Gaps = 15/153 (9%)
Frame = -1
Query: 403 VAIKTCKNCTSDSVREKFLQEALTMRQFD-HPHIVKLIGVIT-ENPVWIIMELCTLGELR 460
VA+KT +D+ + +FL+E MR+ HP++V +G T +P I+ME C G+L
Sbjct: 459 VAVKTHNEAATDAEKSEFLRELSIMRKLPRHPNVVSFMGCCTMSDPALILMEFCCHGDLL 280
Query: 461 SFLQVRK---------YSLDLASLILYAYQLSTA--LAYLESKRFVHRDIAARNVLVSSN 509
SFL+ R+ + DL + +++ L A +A++ + + VHRD+AARNVL+S
Sbjct: 279 SFLRKRRPDRTVFLTSTANDLTARDFFSFALHVARGMAHVANNKIVHRDVAARNVLISER 100
Query: 510 DCVKLGDFGLSRYMEDS--TYYKASKGKLPIKW 540
+ K+ DFGLSR + D Y S+ LP++W
Sbjct: 99 NVCKVSDFGLSRRVGDQNDVYEIVSRRPLPLRW 1
>18921
Length = 697
Score = 95.5 bits (236), Expect = 9e-20, Method: Compositional matrix adjust.
Identities = 68/232 (29%), Positives = 114/232 (49%), Gaps = 4/232 (1%)
Frame = +2
Query: 376 LGRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHI 435
LG+ +GEG +G V + ++ LA+ K D+ ++ ++E M+Q D +I
Sbjct: 44 LGK-LGEGSYGSVFKSLHKE-TGQVLAI-----KQVPVDTDLQEIIKEISIMQQCDSKYI 202
Query: 436 VKLIGVITENP-VWIIMELCTLGELRSFLQVRKYSL---DLASLILYAYQLSTALAYLES 491
VK G +N +WI+ME C G + +++R +L ++A+++ Y + L YL S
Sbjct: 203 VKYYGSYFKNTDLWIVMEYCGAGSVSDIMRLRNKTLVEREIATILYYTLK---GLXYLHS 373
Query: 492 KRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRF 551
+R +HRDI A N+L+++ KL DFG++ + D+ + + P WMAPE I +
Sbjct: 374 RRKIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTPY-WMAPEVIQEIGY 550
Query: 552 TSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTL 603
+D+W G+ E + G P I G+ P N PP L
Sbjct: 551 DCVADIWSLGITALE-MAEGKPPVMETS-------IL*GQSS*FPTNAPPPL 682
>22005
Length = 873
Score = 95.5 bits (236), Expect = 9e-20, Method: Compositional matrix adjust.
Identities = 76/249 (30%), Positives = 117/249 (46%), Gaps = 58/249 (23%)
Frame = +1
Query: 378 RCIGEGQFGDVHQGIYMSPENPALAVAI-------------KTCKNCTSDSVREKFLQEA 424
R IG+G FG V + ++ LA + K K S+ ++ F +EA
Sbjct: 1 RDIGQGAFGRVSKLKFL-----GLASLVGELIPEKRP*LL*KMLKEDASEDLQSDFEREA 165
Query: 425 LTMRQFDHPHIVKLIGVIT-ENPVWIIMELCTLGELRSFLQV---RKYSL---------- 470
M FDHP+IVKL+GV P+ ++ E + G+L FL++ Y+L
Sbjct: 166 SLMADFDHPNIVKLLGVCAIGKPMCLLFEFMSKGDLNDFLRLCSPENYNLPVSRSQNLVV 345
Query: 471 ------------------------DLASLI-----LY-AYQLSTALAYLESKRFVHRDIA 500
D + ++ LY + Q+S +AYL K +VHRD+A
Sbjct: 346 DLEDGLRVEVEAEECEKDTQSEDRDCSGMLXTKDQLYISQQISAGMAYLAQKDYVHRDLA 525
Query: 501 ARNVLVSSNDCVKLGDFGLSRYMEDSTYYKAS-KGKLPIKWMAPESINFRRFTSASDVWM 559
R V + + DFGL+R + YY+ S + +PI+WM E+I + +F++ SDVW
Sbjct: 526 TRTVXSRTT*-S*ISDFGLARSVHSVDYYRGSEQDAIPIRWMPLEAILYSKFSTQSDVWS 702
Query: 560 FGVCMWEIL 568
FGV +WEIL
Sbjct: 703 FGVVLWEIL 729
>17637
Length = 447
Score = 89.7 bits (221), Expect = 5e-18, Method: Compositional matrix adjust.
Identities = 46/128 (35%), Positives = 70/128 (54%), Gaps = 1/128 (0%)
Frame = +1
Query: 503 NVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKL-PIKWMAPESINFRRFTSASDVWMFG 561
N ++ VKL D LSR + Y G+ PIKW++ E++ + SDVW FG
Sbjct: 1 NCVIDDQLRVKLTDSALSRDLFSGDYNCLGDGEYRPIKWLSLEALQKSHYNEGSDVWSFG 180
Query: 562 VCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRF 621
V MWE+ G P+ + ++ +++G RL P NCP L+++M CWA P+ RP F
Sbjct: 181 VLMWEMCTLGKLPYAEIDPYEMEHYLKDGYRLAQPFNCPDELFTIMAYCWASMPAERPSF 360
Query: 622 TELKAQLS 629
++L+ LS
Sbjct: 361 SQLQICLS 384
>13305
Length = 549
Score = 87.4 bits (215), Expect = 3e-17, Method: Composition-based stats.
Identities = 37/100 (37%), Positives = 57/100 (57%)
Frame = +2
Query: 535 KLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLP 594
++PI+WMA ES+ +T+ SDVW FGV +WEI G P+ + +++G RL
Sbjct: 8 RVPIRWMAVESLFNNTYTTQSDVWSFGVVLWEIFTLGGTPYSSTDTQQLFAFLKDGYRLK 187
Query: 595 MPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEE 634
P C Y++M +CW + RRP F EL +L +L++
Sbjct: 188 RPKLCDQNTYAMMLQCWNENAQRRPTFPELCGRLQRMLDD 307
>01718
Length = 959
Score = 87.0 bits (214), Expect = 3e-17, Method: Compositional matrix adjust.
Identities = 73/271 (26%), Positives = 111/271 (40%), Gaps = 14/271 (5%)
Frame = +3
Query: 380 IGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLI 439
IG G F +V + + + + K T S R L+E + + H +I++ +
Sbjct: 171 IGAGFFSEVFKVTH------RITGQVMALKMNTMTSNRHNMLREVQLLNRLQHANILRFM 332
Query: 440 GV-ITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRD 498
GV + E + + E G L L+ + L I L+ L YL S RF+HRD
Sbjct: 333 GVCVHEGQLHALTEYIPSGNLEQLLEKKDEELPWTQRIQLTLGLARGLDYLHSTRFIHRD 512
Query: 499 IAARNVLVSSNDC----VKLGDFGLSRYMEDSTYYKASKGKLPI----KWMAPESINFRR 550
+ ++N+L+ D + DFGL+ + D K KLP WMAPE +N
Sbjct: 513 LTSKNILIRREDNHGYHAVIADFGLATKIPDPL----DKEKLPTVGSPYWMAPEVLNGHF 680
Query: 551 FTSASDVWMFGVCMWEILMH-----GVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYS 605
+ +D++ G+ M EI + P D + E M CP
Sbjct: 681 YNERADLFSVGIIMCEITARIPADPDIMPRMNNFGVDYVALSE------MISYCPLDYLQ 842
Query: 606 LMTKCWAYDPSRRPRFTELKAQLSTILEEEK 636
L KC DP +RPR E+ L I + K
Sbjct: 843 LAFKCCQVDPQKRPRGVEIIEWLEKIFKNLK 935
>00300
Length = 2318
Score = 86.3 bits (212), Expect = 5e-17, Method: Compositional matrix adjust.
Identities = 73/272 (26%), Positives = 121/272 (44%), Gaps = 13/272 (4%)
Frame = -1
Query: 366 DYEIQRERIEL----GRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSD--SVREK 419
DY I R+ G IGEGQFG V+ + MS +A+K K +D +RE
Sbjct: 1688 DYRINVRRVNFRWQRGNKIGEGQFGKVYTAVNMST---GELMALKEMKFQPNDLQQLRE- 1521
Query: 420 FLQEALTMRQFDHPHIVKLIGV-ITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILY 478
E H ++VK GV + ++ + + ME C G + + K L + Y
Sbjct: 1520 MCDEIKIFEGIQHENLVKYYGVEVHKDEMLMFMEYCDTGTIE---EAAKMGLPEYLIRRY 1350
Query: 479 AYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKL-- 536
++ A+ +L VHRDI N+ ++SN VKLGDFG S ++ T L
Sbjct: 1349 TREIVLAVNHLHENSIVHRDIKGANIFLTSNGHVKLGDFGCSVKLKSHTTMPGEFHNLVG 1170
Query: 537 PIKWMAPESINFRR---FTSASDVWMFGVCMWEILMHGVKPFQGVKNN-DVIGRIENGER 592
+MAPE + A+D+W G + E+ G +P+ + NN ++ ++ G +
Sbjct: 1169 TTAYMAPEVFTQNDQGGYGRAADIWSLGCVVIEMAT-GKRPWHDLDNNYQIMYKVGIGHK 993
Query: 593 LPMPPNCPPTLYSLMTKCWAYDPSRRPRFTEL 624
+P + + +DP++R ++L
Sbjct: 992 PAVPDSLSVEGKHFLDLIMCHDPAQRALASQL 897
>19301
Length = 712
Score = 82.4 bits (202), Expect = 8e-16, Method: Compositional matrix adjust.
Identities = 52/156 (33%), Positives = 83/156 (53%), Gaps = 1/156 (0%)
Frame = +2
Query: 366 DYEIQRERIELGRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEAL 425
D+EI E I +G G G V G + E VA+K ++ +R
Sbjct: 287 DWEIPFESITDLEWLGSGAQGAVFLGKLCAEE-----VAVKKVRDIKETDIR-------- 427
Query: 426 TMRQFDHPHIVKLIGVITENPVW-IIMELCTLGELRSFLQVRKYSLDLASLILYAYQLST 484
+R+ +HP+I+ GV T+ P + IIME C G+L L+ K + A ++ ++ Q+++
Sbjct: 428 NLRKLNHPNIISFKGVCTQAPCYCIIMEYCPYGQLYEVLRDGK-EIPPALVLDWSKQIAS 604
Query: 485 ALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLS 520
+ YL S + +HRD+ + NVLV+ ND VK+ DFG S
Sbjct: 605 GMNYLHSHKIIHRDLKSPNVLVAKNDVVKISDFGTS 712
>12721
Length = 821
Score = 77.8 bits (190), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 66/247 (26%), Positives = 103/247 (41%), Gaps = 8/247 (3%)
Frame = +1
Query: 380 IGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLI 439
IGEG G V I S + +AV + RE E + MR + HP+IV++
Sbjct: 112 IGEGSTGIV--CIATSRDGRQMAVKKMDLRK---QQRRELLFNEVVVMRDYHHPNIVEMY 276
Query: 440 G-VITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRD 498
+ + +W++ME G L V +D + ALA+L + +HRD
Sbjct: 277 NSYLVNDELWVVMEFMEGGALTDI--VTNNRMDEVQIATVCRACLKALAFLHANGVIHRD 450
Query: 499 IAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVW 558
I + ++L+S + VKL DFG + + S P WMAPE I+ + D+W
Sbjct: 451 IKSDSILLSHDGKVKLXDFGFCAQVTQDLQKRKSLVGTPY-WMAPEVISRLPYGPEVDIW 627
Query: 559 MFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPP-------NCPPTLYSLMTKCW 611
G+ + E ++ PF + RI + MPP P L + +
Sbjct: 628 SLGIMVME-MIDAEPPFFNEPPLQAMRRIRD-----MPPPKLRNTHKISPRLQGFIDRML 789
Query: 612 AYDPSRR 618
DP +R
Sbjct: 790 VRDPHQR 810
>14420
Length = 528
Score = 74.7 bits (182), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 45/167 (26%), Positives = 78/167 (46%), Gaps = 1/167 (0%)
Frame = +2
Query: 410 NCTSDSVREKFLQEALTMRQFDHPHIVK-LIGVITENPVWIIMELCTLGELRSFLQVRKY 468
N + +E + E L MR+ +P+IV L + +W++ME G L V +
Sbjct: 11 NLSQQPKKELIINEILVMRENQNPNIVNYLDSYLVGEELWVVMEFLAGGSLTDV--VTET 184
Query: 469 SLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTY 528
+D + + AL +L + +HRDI + N+L+ + VKL DFG +
Sbjct: 185 CMDEGQIAAVCRECLQALEFLHENQVIHRDIKSDNILLGMDGSVKLTDFGFCAQLSPEQS 364
Query: 529 YKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPF 575
+++ P WMAPE + +++ D+W GV E ++ G P+
Sbjct: 365 KRSTMVGTP-YWMAPEVVTRKQYGPTVDIWSLGVMCIE-MIEGEPPY 499
>13592
Length = 980
Score = 73.6 bits (179), Expect = 4e-13, Method: Compositional matrix adjust.
Identities = 67/257 (26%), Positives = 118/257 (45%), Gaps = 9/257 (3%)
Frame = +2
Query: 380 IGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEAL-TMRQFDHPHIVKL 438
IG+G+FG V+ + N +A+K ++ K + E L + H ++V+
Sbjct: 8 IGQGRFGKVYTAV---NNNTGELMAMKEIAIQPGETRALKNVAEELKILEGIKHKNLVRY 178
Query: 439 IGV-ITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHR 497
G+ + + I MELC+ G L S +++ L A + QL + +A L VHR
Sbjct: 179 YGIEVHREELLIFMELCSEGTLESLVELTG-GLPEALSRRFTAQLLSGVAELHKHGIVHR 355
Query: 498 DIAARNV-LVSSNDCVKLGDFGLSRYMEDSTYYKAS-KGKLPIK-WMAPE---SINFRRF 551
DI N+ LV ++ +KLGDFG + ++ T +G + + +MAPE N
Sbjct: 356 DIKTANIFLVDGSNSLKLGDFGSAVKIQAHTTVPGELQGYVGTQAYMAPEVFTKTNSDGH 535
Query: 552 TSASDVWMFGVCMWEILMHGVKPFQGVKNN-DVIGRIENGERLPMPPNCPPTLYSLMTKC 610
+D+W G + E + G +P+ +N ++ ++ GE+ P + + + C
Sbjct: 536 GRLADIWSVGCVVVE-MASGKRPWAQFDSNFQIMFKVGMGEKPQAPESLSQEGHDFIDHC 712
Query: 611 WAYDPSRRPRFTELKAQ 627
+DP +R EL Q
Sbjct: 713 LQHDPKQRLSAIELLEQ 763
>27546
Length = 426
Score = 69.3 bits (168), Expect = 7e-12, Method: Composition-based stats.
Identities = 35/114 (30%), Positives = 65/114 (57%), Gaps = 1/114 (0%)
Frame = -1
Query: 414 DSVREKFLQEALTMRQFDHPHIVKLIGVITENP-VWIIMELCTLGELRSFLQVRKYSLDL 472
D V++ F +E + + DHP+I+++ ++ P ++I M G++ S ++ + +D
Sbjct: 357 DFVKKFFPRELEILTRLDHPNIIQIHSILQRGPKIFIFMRYAEKGDMLSHIK-KTGPIDE 181
Query: 473 ASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDS 526
A ++ +Q++ AL YL S HRD+ N+L+S VK+ DFG +RY D+
Sbjct: 180 AQTKVWFFQMAKALQYLHSHDIAHRDLKCENILLSKRLNVKIADFGFARYCRDA 19
>30755
Length = 1137
Score = 68.9 bits (167), Expect = 9e-12, Method: Compositional matrix adjust.
Identities = 44/143 (30%), Positives = 76/143 (53%), Gaps = 1/143 (0%)
Frame = +2
Query: 477 LYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKL 536
Y ++ +AL YL S+ ++RD+ N+L+ + +K+ DFGL + ED TY + +K
Sbjct: 44 FYGAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCK--EDITYGRTTKTFC 217
Query: 537 PI-KWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPM 595
+++APE ++ + A D W GV M+E++ G PF +++DV+ + E +
Sbjct: 218 GTPEYLAPEVLDDNDYGRAVDWWGTGVVMYEMIC-GRLPFYN-RDHDVLFTLILVEDVKF 391
Query: 596 PPNCPPTLYSLMTKCWAYDPSRR 618
P N SL++ A DP R
Sbjct: 392 PRNITDEAKSLLSGLLAKDPRNR 460
>00715
Length = 1788
Score = 67.8 bits (164), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 59/253 (23%), Positives = 110/253 (43%), Gaps = 34/253 (13%)
Frame = +1
Query: 401 LAVAIKTCKNCTSDSVREKFLQEALTMR-QFDHPHIVKLIGVIT----ENPVWIIMELCT 455
+AV I ++ ++R+ + E L R H ++V ++G + E+ W+ ME
Sbjct: 7 VAVKIYHKRSSNPRALRQSYSNELLAFRCGLRHVNVVSILGATSLHRFEDGAWLAMEYVG 186
Query: 456 LGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLG 515
L++ L + +D + + A Q++ L YL S VH D+ N L++ + +++
Sbjct: 187 PLNLQTILNDHQQDIDSSMRLSLALQMARGLHYLHSINIVHLDLKPANCLLTRDLKLRIA 366
Query: 516 DFGLSRYM-------------------EDSTYYKASKGKLP--IKWMAPESINFRRFTSA 554
DFG + E + A K +L + + APE + + +
Sbjct: 367 DFGCCHQLTPTGLDMGEREGGMAGNELELTPVQGAWKNELAGTLAYRAPELLKGLQPSVR 546
Query: 555 SDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPT--------LYSL 606
SDV+ G+ +W++ P++GV + V+ ++ + + P PP P T L
Sbjct: 547 SDVYSLGITLWQMCTRQ-GPYEGVPAHAVVYQVVSKDLRPCPP--PSTEDDPFEVMFRDL 717
Query: 607 MTKCWAYDPSRRP 619
T+CWA RP
Sbjct: 718 YTQCWARRVEDRP 756
>13066
Length = 551
Score = 67.0 bits (162), Expect = 4e-11, Method: Compositional matrix adjust.
Identities = 49/174 (28%), Positives = 82/174 (47%), Gaps = 10/174 (5%)
Frame = +3
Query: 398 NPALAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITENPV-WIIMELCTL 456
N LA I + D V + F +E + + DHP+I+++ ++ P +I M
Sbjct: 51 NIKLACKIIDKEKAPVDFVEKFFPRELDLLTKLDHPYIIQIHSILQRXPKNFIFMRFAER 230
Query: 457 GELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGD 516
G+L +++Q + + + I + YQ++TAL YL S HRD+ N+L+SS+ VKL D
Sbjct: 231 GDLLTYIQEVGFVKEKQAKIWF-YQMTTALNYLHSYDVAHRDLKCENILLSSHFNVKLAD 407
Query: 517 FGLS---------RYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFG 561
FG + +YM + A+ I + AP + +D W G
Sbjct: 408 FGFACACITESGEKYMSRTYCGSAAYAAPEIVYGAPYA------PKVADAWSLG 551
>31885
Length = 529
Score = 66.6 bits (161), Expect = 4e-11, Method: Compositional matrix adjust.
Identities = 46/148 (31%), Positives = 77/148 (52%), Gaps = 6/148 (4%)
Frame = -2
Query: 427 MRQFDHPHIVKL-IGVITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTA 485
+ + DHP +V L E ++++++L G+LR +Q ++ S + Y QL+
Sbjct: 510 LTRLDHPFLVNLWYAFQDEEDLFMVVDLFLGGDLRYHMQ-QEVSFREDCVKFYLCQLALV 334
Query: 486 LAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPE- 544
L YL S++ VHRDI N+L+ + DF ++ +ED ++ G P +MAPE
Sbjct: 333 LDYLRSQKIVHRDIKPDNILLDEQGHCHVTDFNIATQLEDDELATSTSGTRP--YMAPEV 160
Query: 545 ---SINFRR-FTSASDVWMFGVCMWEIL 568
+IN RR + D W GV ++E+L
Sbjct: 159 YGVAINERRGYGFPVDWWSLGVSLFELL 76
>07833
Length = 1504
Score = 66.2 bits (160), Expect = 7e-11, Method: Compositional matrix adjust.
Identities = 53/217 (24%), Positives = 99/217 (45%), Gaps = 7/217 (3%)
Frame = -3
Query: 412 TSDSVREKFLQEALTMRQFDHPHIVKLIGVITENP-VWIIMELCTLGELRSFLQVRK-YS 469
+ + F++E +R F+HP+++ ++ + P + +I + G L + L
Sbjct: 1502 VTKRITRDFMEEFPRLRIFNHPNVLPVLACCNQPPNLVLISQFMPFGSLYNTLHGESGIV 1323
Query: 470 LDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYY 529
+D + +A ++ + +L S + N L++S + D M D +
Sbjct: 1322 VDQNQSLRFAMDIARGMEFLHSM-----EPTIPNFLLTSKHVMIDEDLTARINMADYCFS 1158
Query: 530 KASKGKL-PIKWMAPESINFRR---FTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIG 585
KGK+ WMAPE++ R T A+D+W F + MWE+ V PF + + +V
Sbjct: 1157 FHEKGKVYSPAWMAPEALQRRPDDINTRAADMWSFAILMWELETREV-PFAELSSMEVGM 981
Query: 586 RIE-NGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRF 621
++ G R+ +PP + L+ C +P +RPRF
Sbjct: 980 KVALEGLRISIPPGISLHMSRLIKICMNEEPGKRPRF 870
>01060
Length = 1800
Score = 65.9 bits (159), Expect = 9e-11, Method: Compositional matrix adjust.
Identities = 55/228 (24%), Positives = 112/228 (49%), Gaps = 6/228 (2%)
Frame = +1
Query: 348 EDTYTMPSIKSYCIDVARDYEIQRERIELGRCIGEGQFGDVHQGIYMSPENPALAVAIKT 407
EDT T +K + D+E + + IGEG +G V++ + + +A+K
Sbjct: 1 EDTLTCLLLKLNIKRLMMDFETALSDLTDFQKIGEGTYGVVYKCRHRATGR---KLAMKK 171
Query: 408 CK-NCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITENP-VWIIMELCTLGELRSFLQV 465
+ + D V ++E +R+ H +IV L VI E+ ++++ E ++ +L+ ++
Sbjct: 172 IRLRGSEDGVPSSAIREIAMLRELRHTNIVCLEDVIMEDERLFLVFEFLSM-DLKMYIDK 348
Query: 466 --RKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYM 523
LD + Y +Q+ T + + +R VHRD+ +N+L++ +K+ DFG++R
Sbjct: 349 FPEGVVLDRRLVKSYVFQIVTGIXFCHQRRIVHRDLKPQNLLINHTGAIKIADFGMARTF 528
Query: 524 EDSTYYKASKGKLPIKWM-APESI-NFRRFTSASDVWMFGVCMWEILM 569
+ +A ++ W APE + ++++ DVW G ++L+
Sbjct: 529 --ALPVRAYTHEVVTLWYRAPEILMGASKYSTPVDVWSIGTIFADMLI 666
>09606
Length = 1300
Score = 65.1 bits (157), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 68/292 (23%), Positives = 118/292 (40%), Gaps = 37/292 (12%)
Frame = -3
Query: 380 IGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLI 439
+G+G+ +++G N I+ CK R + HP++V+
Sbjct: 1091 LGKGEHSIIYKGRRKGTINFVAIHCIEKCK-------RPEVTNTVRMTHDISHPNVVQFH 933
Query: 440 GVI-TENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRD 498
T N +W+++ELCT G L L + + L S+ + L T L Y+ S + D
Sbjct: 932 EWYETSNHLWLVVELCTGGSLADIL-AQDHHLPETSIRDFGIHLVTGLHYIHSLGILFHD 756
Query: 499 IAARNVLVSSNDCVKLGDFGLSRY----MEDSTYYKASKG-------------KLPIK-- 539
+ VL+ ++ +K DFGLS+ +E+ + A G ++P
Sbjct: 755 LRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQWNIQSAEEMMKQVPTSGS 576
Query: 540 --WMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIEN-------- 589
+MAPE + SD+W G +E + G PF G + ++ N
Sbjct: 575 PTYMAPEVFQGAEPSIMSDLWALGCVFYE-MFSGHPPFLGETYDITKDKVLNKEFPLPKV 399
Query: 590 -GERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTEL------KAQLSTILEE 634
G RL P+ P +L+ D +RR + L + LS++++E
Sbjct: 398 KGSRLSAKPS--PEFLNLLESLLQKDSTRRLSWASLVKHAFWQGGLSSLVKE 249
>14126
Length = 1265
Score = 62.8 bits (151), Expect = 7e-10, Method: Compositional matrix adjust.
Identities = 60/237 (25%), Positives = 110/237 (46%), Gaps = 18/237 (7%)
Frame = +3
Query: 379 CIGEGQFGDVHQGIYMSPENPALAVAIKTCK-NCTSDSVREKFLQEALTMRQ---FDHPH 434
IG G +G V++ + N VA+K + N T + + ++E ++Q ++HP+
Sbjct: 210 VIGNGAYGTVYKARDL--RNQGEFVAMKRIRLNNTEEGMPMMAIREISMLKQLEQYEHPN 383
Query: 435 IVKLIGVITENPVWIIMELCTLGELRSFLQVRKYSLDLASLIL--------------YAY 480
+V+L+ V + N + T E+R L DLA+ +
Sbjct: 384 VVRLLDV-SHNTI-------TDREIRLNLVFEYIEHDLATYLAKCPSPGLGPDRIKDLML 539
Query: 481 QLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKW 540
QL + +L S R VHRD+ +N+L+S + +KL DFGL+R S + + + + +
Sbjct: 540 QLLNGVDFLHSNRIVHRDLKPQNLLISKDGRLKLADFGLARIY--SFHMALTTVVVTLWY 713
Query: 541 MAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPP 597
+PE + + ++ D+W G C++ L F+G D + +I E + +PP
Sbjct: 714 RSPEVLMQAEYGTSVDIWSCG-CIFAELFTRRALFKGSSEFDQLKKI--FEVIGLPP 875
>19094
Length = 898
Score = 61.6 bits (148), Expect = 1e-09, Method: Composition-based stats.
Identities = 34/114 (29%), Positives = 62/114 (54%), Gaps = 3/114 (2%)
Frame = +1
Query: 457 GELRSFLQVRKYSL---DLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVK 513
G + +++R +L ++A+++ Y + L YL S+R +HRDI A N+L+++ K
Sbjct: 10 GSVSDIMRLRNKTLVEREIATILYYTLK---GL*YLHSRRKIHRDIKAGNILLNNEGHAK 180
Query: 514 LGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEI 567
L DFG++ + D+ + + P WMAPE I + +D+W G+ E+
Sbjct: 181 LADFGVAGQLTDTMAKRNTVIGTPY-WMAPEVIQEIGYDCVADIWSLGITALEM 339
>13212
Length = 1067
Score = 61.6 bits (148), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 51/196 (26%), Positives = 84/196 (42%), Gaps = 18/196 (9%)
Frame = -1
Query: 447 VWIIMELCTL---GELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARN 503
VW I+++ + G L S + + + A + +++ AL +L +HRDI A N
Sbjct: 1067 VWXIVDVFRVLWWGALDSIMVDLEKPMTEAQICYVCHEMCMALDFLHRHHVIHRDIKAGN 888
Query: 504 VLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAP-----ESINFRRFTSASDVW 558
VL++ + VKL DFG+S + + + P WMAP E++ + +D+W
Sbjct: 887 VLLTIDGEVKLADFGVSAKNTQTQQKRDTFIGTPY-WMAPEVVLCETLKDTPYDFKADIW 711
Query: 559 MFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTL----------YSLMT 608
GV + E P + + V+ +I + PPTL +
Sbjct: 710 SLGVTLIE-FAQIEPPNKEMHPMRVLIKIHKSD--------PPTLEKPKKWTKLFKDFIA 558
Query: 609 KCWAYDPSRRPRFTEL 624
KC DP+ RP EL
Sbjct: 557 KCLVKDPNLRPTAAEL 510
>29581
Length = 1278
Score = 59.7 bits (143), Expect = 5e-09, Method: Compositional matrix adjust.
Identities = 49/163 (30%), Positives = 78/163 (47%), Gaps = 8/163 (4%)
Frame = -2
Query: 416 VREKFLQEALTMRQFDHPHIVKLIGVI---TENPVWIIMELCTLGELRSFLQVRKYSLDL 472
VR FL L +R H +IV+L V+ + + ++++ME C +L S L
Sbjct: 1208 VRSTFL---LNLR---HQNIVQLQEVVVGKSLDSLFLVMEYCE-QDLASLLDNMPAPFSE 1050
Query: 473 ASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKAS 532
+ + QL L YL +HRD+ N+L++ CVK+ DFGL+R Y K
Sbjct: 1049 SQVKCIVLQLLKGLRYLHEAFIIHRDLKVSNLLMTDKGCVKIADFGLAR-----NYGKPQ 885
Query: 533 KGKLP----IKWMAPESI-NFRRFTSASDVWMFGVCMWEILMH 570
K P + + APE + + ++A D+W G + E+L H
Sbjct: 884 KPMTPKVVTLWYRAPELLFGSKTHSTAIDMWSAGCILGELLGH 756
>01756
Length = 1858
Score = 59.3 bits (142), Expect = 7e-09, Method: Compositional matrix adjust.
Identities = 49/204 (24%), Positives = 90/204 (44%), Gaps = 16/204 (7%)
Frame = -3
Query: 380 IGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKF----LQEALTMRQFDHPHI 435
IG+G FG+V + + VA+K D+ +E F L+E ++ +H ++
Sbjct: 1718 IGQGTFGEVFKA---RCKKTKQVVAMK---KVLMDNEKEGFPITALREIKILQLLNHENV 1557
Query: 436 VKLIGVIT---------ENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTAL 486
V LI + + ++ +++ E C +L L +L + QL L
Sbjct: 1556 VDLIEICSTKATSANRYKSMFYLVFEFCE-HDLAGLLSNMSVVFNLPEIKEVMKQLMNGL 1380
Query: 487 AYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSR-YMEDSTYYKASKGKLPIKWMAPES 545
Y+ + +HRD+ A N+L++ +KL DFGL+R + + ++ W P
Sbjct: 1379 YYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRPPE 1200
Query: 546 INF--RRFTSASDVWMFGVCMWEI 567
+ R +++A D W G M E+
Sbjct: 1199 LLLGDRNYSTAIDQWGAGCIMAEM 1128
>19761
Length = 473
Score = 58.9 bits (141), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 34/130 (26%), Positives = 67/130 (51%), Gaps = 8/130 (6%)
Frame = -3
Query: 475 LILYAYQLSTALAYLESKR--FVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKAS 532
++ + Q ++AL Y+ + +HRD+ +N+ V+ V+LGD GL+R + + S
Sbjct: 417 IVCWLMQTASALNYMHTHTPVILHRDLKPQNIYVTEKGDVRLGDLGLARKLTGPADFATS 238
Query: 533 KGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIG------R 586
+ I +++PE ++ + + S SD+W G ++I G K +D +G +
Sbjct: 237 QVG-TIMYLSPEILSQQPYNSKSDIWSLGCVFYDI--------TGKKGSDEMGVMFLLVQ 85
Query: 587 IENGERLPMP 596
+ G +LP+P
Sbjct: 84 VMGGRKLPLP 55
>04591
Length = 1117
Score = 58.5 bits (140), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 43/158 (27%), Positives = 72/158 (45%), Gaps = 11/158 (6%)
Frame = -2
Query: 421 LQEALTMRQFDHPHIVKLIGVIT---------ENPVWIIMELCTLGELRSFLQVRKYSLD 471
L+E ++Q +H ++V+L + ++ ++I E C +L L +
Sbjct: 1077 LREIKILQQLEHENVVQLQEICHTQAGPYNRYKSTFYLIFEYCDY-DLAGLLNNLRVKFS 901
Query: 472 LASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKA 531
LA QL L Y+ +K+ +HRDI A N+L++ + +KL DFGLSR S K
Sbjct: 900 LADKKNLMSQLLNGLFYIHTKQILHRDIKAANILLTRDGVLKLADFGLSRPWVKS---KR 730
Query: 532 SKGKLPIKWMAPESINF--RRFTSASDVWMFGVCMWEI 567
++ W P + R + D+W G M E+
Sbjct: 729 LTNRVVTLWYRPPELLLGEREYGPEIDMWGVGCIMAEM 616
>03240
Length = 1683
Score = 57.0 bits (136), Expect = 4e-08, Method: Compositional matrix adjust.
Identities = 63/263 (23%), Positives = 108/263 (41%), Gaps = 56/263 (21%)
Frame = -3
Query: 369 IQRERIELGRC-------IGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFL 421
I+ +R ++ +C +G G FG+V + + A+KT + SD ++ +
Sbjct: 1321 IRLKRAKMDKCMFEKIKTLGVGAFGEVS---LCRKNDTGMLYAMKTLRK--SDVLKRNQV 1157
Query: 422 QEALTMRQF----DHPHIVKLIGVITE-NPVWIIMELCTLGELRSFLQVRKYSLDLASLI 476
R D+ +VKL + N ++ +M+ G+L L +R LD
Sbjct: 1156 AHVKAERDILAEADNEWVVKLYYSFQDHNYLYFVMDYVPGGDLMGLL-IRMEILDEPLAR 980
Query: 477 LYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLS---RYMEDSTYYK--- 530
Y +L A+ + F+HRDI N+L+ N +KL DFGL R+ +S YY+
Sbjct: 979 FYVAELVQAIESVHRMGFIHRDIKPDNILIDRNGHIKLTDFGLCTGFRWTHNSKYYQRDG 800
Query: 531 --ASKGKLPIK-----------------------------------WMAPESIN-FRRFT 552
A + + +K ++APE ++ +T
Sbjct: 799 THARQDSMEVKCQLDEQCQCEILKPLERRRKREQRCLAHSLVGTPNYIAPEVLSRLGGYT 620
Query: 553 SASDVWMFGVCMWEILMHGVKPF 575
S D W GV ++E+L+ G PF
Sbjct: 619 SVCDWWSVGVILFEMLV-GHPPF 554
>21079
Length = 878
Score = 56.6 bits (135), Expect = 5e-08, Method: Compositional matrix adjust.
Identities = 34/128 (26%), Positives = 66/128 (51%), Gaps = 2/128 (1%)
Frame = +1
Query: 449 IIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSS 508
++ME GEL + + L + + Q+ + + Y+ ++ +H D+ NVL S
Sbjct: 55 LVMEFVGAGELFERVIRDDFVLTERDCVHFVRQICSGVGYMHTQSILHLDLKPENVLCVS 234
Query: 509 NDC--VKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWE 566
++ +K+ DFGL+R+ + + G P +++APE +N+ +D+W GV +
Sbjct: 235 DNSNQIKIIDFGLARFYKPGDSLQVLFGT-P-EFIAPEVVNYDEINFTTDMWSIGVICY- 405
Query: 567 ILMHGVKP 574
IL+ G+ P
Sbjct: 406 ILLSGLSP 429
>01707
Length = 757
Score = 55.5 bits (132), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 53/199 (26%), Positives = 90/199 (45%), Gaps = 10/199 (5%)
Frame = +1
Query: 380 IGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKF-LQEALTMRQFDHPHIVKL 438
IGEG +G V + + + VAIK D + +K ++E ++Q HP++V+L
Sbjct: 88 IGEGSYGVVFK---CRNKETSQLVAIKKFVESEDDPLIKKIAMREIRMLKQLKHPNLVRL 258
Query: 439 IGVITENP----VWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRF 494
I V V+ ++ L EL + R + I+Y Q A+ +
Sbjct: 259 IEVFRRKKRLHLVFDYVDHTLLNELDRY--PRGLPEPMVKRIIY--QTLLAVNFCHQYNT 426
Query: 495 VHRDIAARNVLVSSNDCVKLGDFGLSRYM----EDSTYYKASKGKLPIKWMAPE-SINFR 549
+HRD+ N+L++ VKL DFG +R + ++ T Y A++ + APE +
Sbjct: 427 IHRDVKPENILITRQGQVKLCDFGFARILTGPGDEYTDYVATRW-----YRAPELLVGDT 591
Query: 550 RFTSASDVWMFGVCMWEIL 568
++ DVW G E+L
Sbjct: 592 QYGPPVDVWAIGCVFAELL 648
>18484
Length = 635
Score = 55.5 bits (132), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 28/113 (24%), Positives = 59/113 (52%)
Frame = +1
Query: 477 LYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKL 536
YA +++ L +L + ++RD+ NV++ S +K+ DFG+ + +
Sbjct: 55 FYAAEIAVGLFFLHDQGIIYRDLKLDNVMLDSEGHIKIADFGMCKEGMTGDATTRTFCGT 234
Query: 537 PIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIEN 589
P ++APE + ++ ++ + D W +GV ++E+L G PF G +++ I +
Sbjct: 235 P-DYIAPEIVLYQPYSKSVDWWAYGVLLFEMLA-GQPPFDGEDEDELFSSITD 387
>07836
Length = 1478
Score = 54.7 bits (130), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 65/260 (25%), Positives = 112/260 (43%), Gaps = 43/260 (16%)
Frame = -1
Query: 417 REKFLQEALTMRQFDHPHIVKLI-----GVITENPVWIIMELCTLGELRSFLQVRKYSLD 471
RE L + + +R H +I+ I G + +++I + G L +L R LD
Sbjct: 1424 RETELYQTVLLR---HENILGFIAADIKGTGSWTQLFLITDYHENGSLHDYLLSR--VLD 1260
Query: 472 LASLILYAYQLSTALAYLESKRF--------VHRDIAARNVLVSSNDCVKLGDFGLS-RY 522
+ ++ A+ LA+L + F HRDI ++N+LV N + D GL+ RY
Sbjct: 1259 SSEMLALAHSAICGLAHLHIEIFGTRGKPAIAHRDIKSKNILVKKNGTCCIADLGLAVRY 1080
Query: 523 MEDSTYYKASKG--KLPIKWMAPESI-------NFRRFTSASDVWMFGVCMWEI----LM 569
+ +S + + ++MAPE + NF F A D++ FG+ MWEI ++
Sbjct: 1079 ISESNEVDVAPNPRQGTKRYMAPEVLEMLLNVKNFDAFKQA-DMYAFGLVMWEIARCCVI 903
Query: 570 HGVK-----PFQGVKNND--------VIGRIENGERLPMPPNCPP---TLYSLMTKCWAY 613
GV PF +D V+ + +P+ P + +M +CW+
Sbjct: 902 GGVAEEYQVPFYNCLPHDPSFEDVRLVVSVDKVRPDIPLRWQEDPIMKVMVKVMCECWSG 723
Query: 614 DPSRRPRFTELKAQLSTILE 633
+P+ R +K L + E
Sbjct: 722 NPAARLTALRVKKTLGKLSE 663
>01966
Length = 1735
Score = 53.9 bits (128), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 30/113 (26%), Positives = 62/113 (54%), Gaps = 3/113 (2%)
Frame = -1
Query: 412 TSDSVREKFLQEALTMRQFDHPHIVKLIGVITENP-VWIIMELCTLGELRSFLQV--RKY 468
+ D V ++E +R+ H +IV L VI E+ ++++ E ++ +L+ ++
Sbjct: 1597 SEDGVPSSAIREIAMLRELRHTNIVCLEDVIMEDERLFLVFEFLSM-DLKMYIDKFPEGV 1421
Query: 469 SLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSR 521
LD + Y +Q+ T + + +R VHRD+ +N+L++ +K+ DFG++R
Sbjct: 1420 VLDRRLVKSYVFQIVTGINFCHQRRIVHRDLKPQNLLINHTGAIKIADFGMAR 1262
>26711
Length = 405
Score = 50.8 bits (120), Expect = 3e-06, Method: Composition-based stats.
Identities = 32/102 (31%), Positives = 58/102 (56%), Gaps = 5/102 (4%)
Frame = -2
Query: 481 QLSTALAYLESKRFVHRDIAARNVLVSSN--DCVKLGDFGLSRYM---EDSTYYKASKGK 535
Q+ L ++ ++ VH D+ N+L+S + D V+L DFGL+R + +++ + G
Sbjct: 392 QVLDILQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARKLYPPQETFLNHGTPG- 216
Query: 536 LPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQG 577
+ +PE+++ + ++ASDVW GV + IL+ G PFQ
Sbjct: 215 ----FTSPEALDVKPISTASDVWGVGVLAY-ILLSGQSPFQA 105
>15910
Length = 1361
Score = 50.8 bits (120), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 34/110 (30%), Positives = 56/110 (50%), Gaps = 3/110 (2%)
Frame = +2
Query: 485 ALAYLESKRFVHRDIAARNVL---VSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWM 541
+ Y+ + VHRD+ N+L ++ + +KL DFGLSR +E G P +
Sbjct: 500 GVQYIHANGVVHRDLKPENLLYECMTDDSKLKLADFGLSRIIEPEVQMSTVCGT-P-GYC 673
Query: 542 APESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGE 591
APE + ++T + D+W GV + IL+ G +PF ++ +I GE
Sbjct: 674 APEVLKGDKYTPSVDMWSVGVIAY-ILLCGYEPFFAENEFEMYRKIIKGE 820
>25550
Length = 941
Score = 49.3 bits (116), Expect = 8e-06, Method: Compositional matrix adjust.
Identities = 25/76 (32%), Positives = 37/76 (48%), Gaps = 1/76 (1%)
Frame = +3
Query: 560 FGVC-MWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRR 618
G C +W++ + GV +V +E G R+ P P +Y LM KCW +DP R
Sbjct: 12 MGACDIWDVX------YPGVDLTEVYHLLERGYRMERPQGTPADVYILMLKCWQWDPKER 173
Query: 619 PRFTELKAQLSTILEE 634
P F E+ L + E+
Sbjct: 174 PTFKEIHYLLENMFEK 221
>12672
Length = 773
Score = 48.9 bits (115), Expect = 9e-06, Method: Compositional matrix adjust.
Identities = 38/162 (23%), Positives = 69/162 (42%), Gaps = 16/162 (9%)
Frame = +3
Query: 483 STALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGL---SRYMEDSTYYKASKGKLPIK 539
++ + YL VHRDI N+L+ S K+GDF + E T AS
Sbjct: 21 ASGIQYLNDNGHVHRDIKTANILLDSEYTAKVGDFATVVSAPSGEGKTVQNASVVIGTAA 200
Query: 540 WMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPF----QGVKNNDVIGRIENGERL-- 593
++APE+I+F ++ D + FGV + E++ V + ++ ++ +E E +
Sbjct: 201 YLAPEAIHF-DVSTKLDSYSFGVVLLEVITGLVAQDYSREERTLSSHIMENVEEPEEIHD 377
Query: 594 -------PMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQL 628
P LY + +C +RP +++ +L
Sbjct: 378 FVDQSAGTWPDGAVDKLYDISMRCLNLSKKQRPNVKDIRPEL 503
>32264
Length = 287
Score = 48.5 bits (114), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 21/48 (43%), Positives = 28/48 (58%)
Frame = +1
Query: 587 IENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEE 634
IE+G RL P P ++Y LM +CW Y P +RP F EL L I+ +
Sbjct: 1 IEDGYRLQQNPQTPDSVYKLMLRCWEYVPEKRPHFKELYTSLKDIVRK 144
>21433
Length = 590
Score = 48.1 bits (113), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 30/98 (30%), Positives = 49/98 (50%)
Frame = +2
Query: 478 YAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLP 537
Y YQLS+AL Y ++ +HRDI N+L+ +K+ DFG S + S + +
Sbjct: 182 YIYQLSSALEYCHYRKVIHRDIKPENLLLGLKGDLKIADFGWSVHAPSS---RRTTMCGT 352
Query: 538 IKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPF 575
+ ++ PE + + D+W GV +E L+ G P
Sbjct: 353 LDYLPPEMVEGKTHDENVDLWSLGVLCYEFLV-GTPPL 463
>28157
Length = 400
Score = 46.2 bits (108), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 31/112 (27%), Positives = 54/112 (48%), Gaps = 6/112 (5%)
Frame = +3
Query: 413 SDSVREKFLQEALTMRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVR--KYSL 470
S+ ++ F+QE + + HP+IV L G ++PV ++ME G L + L +
Sbjct: 30 SEQEKKSFMQELKQLSRVSHPNIVCLYGACRDHPVCLVMEYAEGGSLYNVLHGSGPQPQY 209
Query: 471 DLASLILYAYQLSTALAYLES---KRFVHRDIAARN-VLVSSNDCVKLGDFG 518
A + + Q + + YL K +HRD+ N +L+ +K+ DFG
Sbjct: 210 TAAHAMNWLLQCALGVEYLHGMKPKALIHRDLKPPNLLLIQCGTKLKICDFG 365
>26560
Length = 398
Score = 43.9 bits (102), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 32/113 (28%), Positives = 58/113 (51%), Gaps = 1/113 (0%)
Frame = -1
Query: 477 LYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKL 536
YA ++ L ++ S+ V+RD+ N+L+ N V++ D GL+ D + +
Sbjct: 344 FYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGLA---CDFSKKRPHASVG 174
Query: 537 PIKWMAPESI-NFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIE 588
+MAPE + + + S++D + FG CM L+ G PF+ ++N RI+
Sbjct: 173 THGYMAPEVLMKGQSYDSSADWFSFG-CMLYKLLKGHSPFR--QHNQGQARID 24
>04138
Length = 800
Score = 43.5 bits (101), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 24/85 (28%), Positives = 42/85 (49%), Gaps = 3/85 (3%)
Frame = +1
Query: 486 LAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSR-YMEDSTYYKASKGKLPIKWMAPE 544
L Y+ + +HRD+ A N+L++ +KL DFGL+R + + ++ W P
Sbjct: 52 LYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRPP 231
Query: 545 SINF--RRFTSASDVWMFGVCMWEI 567
+ R +++A D W G M E+
Sbjct: 232 ELLLGDRNYSTAIDQWGAGCIMAEM 306
>01392
Length = 1806
Score = 42.0 bits (97), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 37/123 (30%), Positives = 59/123 (47%), Gaps = 12/123 (9%)
Frame = -1
Query: 473 ASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSND---CVKLGDFGLSRYME-DSTY 528
ASL++ ++ AL +L SK HRD+ N+L D VK+ DF L+ + D
Sbjct: 1785 ASLVVR--HIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGISCDGDG 1612
Query: 529 YKASKGKLPI---KWMAPESINFRRFTSAS-----DVWMFGVCMWEILMHGVKPFQGVKN 580
K + P+ ++MAPE ++ S S D+W G+ ++ I++ G PF G
Sbjct: 1611 TKTPELLTPVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILY-IMLCGYPPFYGQCG 1435
Query: 581 NDV 583
D
Sbjct: 1434 EDC 1426
>12786
Length = 460
Score = 41.2 bits (95), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 39/143 (27%), Positives = 69/143 (48%), Gaps = 23/143 (16%)
Frame = -3
Query: 469 SLDLASLILYAYQLSTALAYLESKRFVHRDIAARN-VLVSSNDCVKLGDFGLSRYMED-- 525
LD + Y ++ A+ L ++ +H D+ N +LV+ N +KL DFG++ ++
Sbjct: 422 GLDRMMIKFYWREMLRAVKALHNEGVIHSDLKPANFMLVAGN--LKLIDFGIANTLQQDK 249
Query: 526 STYYKASKGKLPIKWMAPESINFRRFTSA--------------------SDVWMFGVCMW 565
++ K S+ P +M+PE+I SA SDVW G C+
Sbjct: 248 TSVLKDSRVGTP-SYMSPEAIMAACDDSADDSMEEDGHRTKPKYKVGVRSDVWSLG-CIL 75
Query: 566 EILMHGVKPFQGVKNNDVIGRIE 588
+++G PFQ +KNN +G+++
Sbjct: 74 YNMVYGRTPFQHIKNN--MGKLQ 12
>07933
Length = 728
Score = 40.0 bits (92), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 15/39 (38%), Positives = 26/39 (66%)
Frame = +3
Query: 596 PPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEE 634
P CP LY++M +CW+ +PS RP F +L+ + ++E+
Sbjct: 3 PNYCPNLLYNIMMQCWSAEPSARPTFHKLEQDIVAMVEQ 119
>03508
Length = 1463
Score = 39.7 bits (91), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 26/100 (26%), Positives = 48/100 (48%), Gaps = 2/100 (2%)
Frame = +1
Query: 477 LYAYQLSTALAYLESKRFVHRDIAARNVLVS-SNDCVKLGDFGLSRYMEDSTYYKASKGK 535
Y Y+L AL + S +HRD+ NV++ N ++L D+GL+ + Y
Sbjct: 883 FYLYELMKALDFCHSMGIMHRDVKPHNVMIDHENKKLRLIDWGLAEFYHPGMEYNVRVAS 1062
Query: 536 LPIKWMAPE-SINFRRFTSASDVWMFGVCMWEILMHGVKP 574
K PE ++++ + + D+W G CM+ ++ +P
Sbjct: 1063RYFK--GPELLLDYQMYDYSLDMWSLG-CMFASMIFRKEP 1173
>37602
Length = 804
Score = 38.5 bits (88), Expect = 0.014, Method: Compositional matrix adjust.
Identities = 22/71 (30%), Positives = 32/71 (45%)
Frame = -1
Query: 447 VWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLV 506
+WI ME C G ++ V L + + L YL + +HRDI N+L+
Sbjct: 294 LWIAMEYCGGGSMQDIYHVTG-PLTEPQIAFVCRETLKGLHYLHRRGKMHRDIKGANILL 118
Query: 507 SSNDCVKLGDF 517
+ VKL DF
Sbjct: 117 TEEGDVKLADF 85
>38046
Length = 446
Score = 38.1 bits (87), Expect = 0.017, Method: Composition-based stats.
Identities = 14/32 (43%), Positives = 24/32 (75%)
Frame = -1
Query: 482 LSTALAYLESKRFVHRDIAARNVLVSSNDCVK 513
++ A+AY+E + F+HR++ RN+LV N+ VK
Sbjct: 98 IADAMAYMEKENFIHRNLGDRNILVGPNNRVK 3
>18481
Length = 437
Score = 37.7 bits (86), Expect = 0.026, Method: Composition-based stats.
Identities = 26/82 (31%), Positives = 44/82 (53%), Gaps = 4/82 (4%)
Frame = -1
Query: 449 IIMELCTLG-ELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVS 507
++MEL LG L + K L ++++ + QL + L ++ K F+HRD+ N L+
Sbjct: 266 LVMEL--LGPSLEELFVICKRRFTLKTILMVSDQLLSRLEFIHQKCFIHRDLKPDNFLMG 93
Query: 508 -SNDCVKLG--DFGLSRYMEDS 526
C +L DFGLS+ +D+
Sbjct: 92 LGRHCHRLYIIDFGLSKRYKDT 27
>11185
Length = 473
Score = 37.4 bits (85), Expect = 0.031, Method: Compositional matrix adjust.
Identities = 37/168 (22%), Positives = 62/168 (36%), Gaps = 21/168 (12%)
Frame = +1
Query: 478 YAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRY----MEDSTYYKASK 533
+ L T L Y+ S + D+ VL+ ++ +K DFGLS+ +E+ + A
Sbjct: 16 FGIHLVTGLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEA 195
Query: 534 G-------------KLPIK----WMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQ 576
G ++P +MAPE + SD+W G +E+
Sbjct: 196 GDQWNIQSAEEMMKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMF-------- 351
Query: 577 GVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTEL 624
+G RL P+ P +L+ D +RR + L
Sbjct: 352 ------------SGSRLSAKPS--PEFLNLLESLLQKDSTRRLSWASL 453
>00486
Length = 797
Score = 35.0 bits (79), Expect = 0.16, Method: Compositional matrix adjust.
Identities = 24/81 (29%), Positives = 36/81 (44%)
Frame = -2
Query: 538 IKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPP 597
I++MAPE + A D W G M+++L G PF I +I G +L +PP
Sbjct: 766 IEYMAPEILTRTGHGKAVDWWSLGALMYDMLT-GSPPFTAENRKKTIDKILKG-KLNLPP 593
Query: 598 NCPPTLYSLMTKCWAYDPSRR 618
L+ K +P+ R
Sbjct: 592 YLTNEARGLIKKLLRKNPAER 530
>26009
Length = 886
Score = 34.7 bits (78), Expect = 0.21, Method: Compositional matrix adjust.
Identities = 15/30 (50%), Positives = 21/30 (70%)
Frame = +3
Query: 481 QLSTALAYLESKRFVHRDIAARNVLVSSND 510
QL +AL ++ SK+ VHRDI NVL+ + D
Sbjct: 735 QLVSALDFMHSKQLVHRDIKPENVLILTPD 824
>16708
Length = 1397
Score = 34.3 bits (77), Expect = 0.28, Method: Compositional matrix adjust.
Identities = 17/49 (34%), Positives = 27/49 (55%)
Frame = -1
Query: 473 ASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSR 521
A + A Q AL ++ VH D+ A NVLV ++ KL D+G+++
Sbjct: 1094 AMVCCIAGQXVCALEHIHELGVVHMDVKADNVLVDAHGNCKLTDYGIAQ 948
>27287
Length = 514
Score = 33.9 bits (76), Expect = 0.31, Method: Compositional matrix adjust.
Identities = 13/37 (35%), Positives = 20/37 (54%)
Frame = -2
Query: 596 PPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTIL 632
PP ++ +M CW DP+ RP F+ L +L +L
Sbjct: 504 PPYASSEMFGIMHSCWQEDPNDRPSFSRLVQELDKML 394
>15741
Length = 402
Score = 33.9 bits (76), Expect = 0.34, Method: Composition-based stats.
Identities = 15/44 (34%), Positives = 24/44 (54%)
Frame = -3
Query: 462 FLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVL 505
FL L +A ++ +A++ + + VHRD+AARNVL
Sbjct: 133 FLTSTANDLTARDFFSFALHVARGMAHVANNKIVHRDVAARNVL 2
>27405
Length = 532
Score = 33.9 bits (76), Expect = 0.34, Method: Compositional matrix adjust.
Identities = 14/44 (31%), Positives = 26/44 (59%)
Frame = -3
Query: 477 LYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLS 520
YA ++ L ++ S+ V+RD+ N+L+ N V++ D GL+
Sbjct: 242 FYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGLA 111
>02638
Length = 1490
Score = 33.5 bits (75), Expect = 0.50, Method: Compositional matrix adjust.
Identities = 28/92 (30%), Positives = 42/92 (45%), Gaps = 5/92 (5%)
Frame = +1
Query: 538 IKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKP---FQGVKNN-DVIGRIENG-ER 592
I +MAPE + + A DVW G M E M +P + N+ +I +I + +
Sbjct: 28 IAFMAPEVLRGESYGRACDVWSVGCVMIE--MCTCRPPWNSHDISNHLALIFKIASSVDP 201
Query: 593 LPMPPNCPPTLYSLMTKCWAYDPSRRPRFTEL 624
P+P N P + LM +C D RP +L
Sbjct: 202 PPIPENMSPPVRDLMLRCLEQDSDFRPSAKDL 297
>21210
Length = 518
Score = 33.1 bits (74), Expect = 0.55, Method: Compositional matrix adjust.
Identities = 30/104 (28%), Positives = 47/104 (45%), Gaps = 7/104 (6%)
Frame = +3
Query: 540 WMAPESINFRR----FTSASDVWMFGVCMWEILMHGVKPFQG-VKNNDVIGRIENGER-- 592
+MAPE I+ R + SDVW G+ + E L G P++ V D + ++ G
Sbjct: 18 YMAPERIDPRASSHGYDVRSDVWSLGITLME-LATGRFPYRKWVSIFDQLQQVVRGVAPC 194
Query: 593 LPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEK 636
LP + + KC D +RP++ +L A L EE+
Sbjct: 195 LPHDGAFSHDFVNFVNKCLTKDEKQRPKYNKLLAHPFVRLYEEQ 326
>25019
Length = 730
Score = 31.6 bits (70), Expect = 1.8, Method: Composition-based stats.
Identities = 22/62 (35%), Positives = 29/62 (46%)
Frame = +3
Query: 500 AARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWM 559
AA NVL+ + VKL DFGL + T + I++MAPE + A D W
Sbjct: 255 AAENVLLDKDGHVKLTDFGLCKEAITGTRVTHTFCG-TIEYMAPEILTRTGHGKAVDWWS 431
Query: 560 FG 561
G
Sbjct: 432 LG 437
>32359
Length = 928
Score = 30.4 bits (67), Expect = 3.5, Method: Compositional matrix adjust.
Identities = 35/128 (27%), Positives = 60/128 (46%), Gaps = 9/128 (7%)
Frame = -1
Query: 377 GRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIV 436
+ IG G FG V+Q + + + VAIK K + + LQ MR+ +H +IV
Sbjct: 415 AKVIGNGSFGVVYQAKLV---DTSELVAIK--KVLQDKRFKNRELQ---IMRKLEHQNIV 260
Query: 437 KLIGVI-----TENPVWI--IMELC--TLGELRSFLQVRKYSLDLASLILYAYQLSTALA 487
KL ++ V++ ++E T+ + K ++ + + LY YQL +LA
Sbjct: 259 KLKFFFYSSGEKKDEVFLNLVLEYVPETVYRVARHYSKSKQTIPILYIKLYMYQLFRSLA 80
Query: 488 YLESKRFV 495
Y+ S+ V
Sbjct: 79 YIHSQACV 56
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000229277 | hsapiens_gene_ensembl | Gamma-enolase
(EC 4.2.1.11) (2-phospho-D-glycerate hydro-lyase) (Neural enolase)
(Neuron-specific enolase) (NSE) (Enolase 2).
[Source:Uniprot/SWISSPROT;Acc:P09104]
(434 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
09637 218 3e-57
26158 133 1e-31
33905 58 7e-09
13259 30 2.7
36511 28 4.9
>09637
Length = 1627
Score = 218 bits (556), Expect = 3e-57, Method: Compositional matrix adjust.
Identities = 101/126 (80%), Positives = 113/126 (89%)
Frame = +1
Query: 306 KFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACKLAQENGW 365
K T+ QIVGDDL VTNPKR++ +E+KACN LLLKVNQIGSVTEAI ACK++Q+ GW
Sbjct: 1 KMTSATDCQIVGDDLLVTNPKRVQTGIEKKACNALLLKVNQIGSVTEAIDACKMSQKEGW 180
Query: 366 GVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEELGDEARFAG 425
GVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQL+RIEEELG +A++AG
Sbjct: 181 GVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLLRIEEELGGKAKYAG 360
Query: 426 HNFRNP 431
NFRNP
Sbjct: 361 ENFRNP 378
>26158
Length = 431
Score = 133 bits (335), Expect = 1e-31, Method: Compositional matrix adjust.
Identities = 66/98 (67%), Positives = 78/98 (79%)
Frame = -2
Query: 3 IEKIWAREILDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGKGV 62
I+KI AR+I DSRGNPTVEVDL T KGLFRAAVPSGASTGIYEA+ELRDGD + Y KGV
Sbjct: 295 IKKIHARQIFDSRGNPTVEVDLTTDKGLFRAAVPSGASTGIYEAVELRDGDPKCYHKKGV 116
Query: 63 LKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGT 100
L AV ++N IA ALI SG+ V Q ++D +++LDGT
Sbjct: 115 LTAVSNVNDKIAQALIESGIPVQNQREVDEFLMKLDGT 2
>33905
Length = 560
Score = 58.2 bits (139), Expect = 7e-09, Method: Compositional matrix adjust.
Identities = 29/73 (39%), Positives = 48/73 (65%), Gaps = 3/73 (4%)
Frame = +2
Query: 361 QENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEELGDE 420
+E G ++++ +GE++D FIADL V + IK GAP R ER++K+N+L++IE EL
Sbjct: 263 EEAGNQIILNACAGESQDDFIADLAVAMNVRFIKIGAPNRGERISKFNRLLQIEAELEAS 442
Query: 421 ARFAG---HNFRN 430
++ A H F++
Sbjct: 443 SKLAPQVDHEFKH 481
>13259
Length = 1751
Score = 29.6 bits (65), Expect = 2.7, Method: Compositional matrix adjust.
Identities = 16/67 (23%), Positives = 33/67 (49%), Gaps = 1/67 (1%)
Frame = +2
Query: 5 KIWAREILDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGKGV-L 63
K+W + ++ PT E++ G+F A + + + ++ D D+ RY +G+
Sbjct: 392 KVWIQACINEDLPPTTELEEGLRNGVFLAKLGHFFAAXVVSLKKIYDKDQTRYKSRGLHF 571
Query: 64 KAVDHIN 70
+ D+IN
Sbjct: 572 RHTDNIN 592
>36511
Length = 169
Score = 28.5 bits (62), Expect = 4.9, Method: Composition-based stats.
Identities = 13/34 (38%), Positives = 22/34 (64%)
Frame = -2
Query: 137 LAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMI 170
L N ++ILP+ A NV N G++ +L+ +FM+
Sbjct: 114 LKDNINIILPITAHNVANIGNNPMKELS*TQFMV 13
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000340940 | hsapiens_gene_ensembl | cAMP-dependent
protein kinase, alpha-catalytic subunit (EC 2.7.11.11) (PKA C-alpha).
[Source:Uniprot/SWISSPROT;Acc:P17612]
(343 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
03240 218 3e-57
30755 170 8e-43
18484 142 2e-34
27405 124 5e-29
00486 120 7e-28
31885 114 4e-26
15910 114 5e-26
18921 110 6e-25
12721 110 1e-24
09606 102 3e-22
26560 101 4e-22
01707 100 1e-21
00300 99 3e-21
14420 99 3e-21
18663 97 8e-21
13592 93 2e-19
26156 82 2e-19
01392 92 4e-19
17975 86 2e-17
13066 84 9e-17
06405 84 1e-16
01060 82 4e-16
21079 80 9e-16
21433 78 5e-15
17722 75 3e-14
01756 74 7e-14
00392 72 2e-13
27546 71 6e-13
09007 70 9e-13
19094 70 2e-12
25019 69 3e-12
01718 69 3e-12
19761 68 4e-12
26711 68 6e-12
11185 65 3e-11
38560 65 3e-11
29581 64 7e-11
13212 64 8e-11
28638 64 9e-11
28157 63 1e-10
14126 62 3e-10
19301 61 7e-10
01966 61 7e-10
21808 59 3e-09
04852 59 4e-09
04591 57 1e-08
32957 57 2e-08
07940 55 5e-08
12786 55 6e-08
04138 54 1e-07
11780 54 1e-07
16708 52 3e-07
03508 52 5e-07
20152 51 8e-07
37602 50 1e-06
00715 50 1e-06
14116 47 8e-06
27274 47 2e-05
17300 46 2e-05
07291 46 2e-05
02638 45 6e-05
17932 44 8e-05
33586 43 1e-04
18401 42 2e-04
12672 41 6e-04
31489 41 0.001
29590 40 0.001
26009 40 0.001
14477 40 0.001
11404 40 0.002
37063 38 0.005
17516 38 0.005
20640 38 0.006
18481 37 0.008
17637 37 0.010
18996 37 0.010
17253 37 0.011
21800 37 0.014
06358 37 0.015
01106 36 0.019
36481 36 0.024
26052 36 0.024
25360 35 0.038
11089 35 0.050
21210 35 0.065
28865 33 0.13
17591 33 0.20
30339 32 0.33
31120 32 0.47
00638 31 0.91
16350 30 1.2
32357 30 1.3
06167 29 3.2
36002 29 3.4
23319 28 4.0
29360 28 7.7
>03240
Length = 1683
Score = 218 bits (555), Expect = 3e-57, Method: Compositional matrix adjust.
Identities = 128/356 (35%), Positives = 192/356 (53%), Gaps = 56/356 (15%)
Frame = -3
Query: 36 FERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPF 95
FE+IKTLG G+FG V L + +TG YAMK L K V+K Q+ H E+ IL + +
Sbjct: 1285 FEKIKTLGVGAFGEVSLCRKNDTGMLYAMKTLRKSDVLKRNQVAHVKAERDILAEADNEW 1106
Query: 96 LVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDL 155
+VKL +SF+D++ LY VM+YVPGG++ L R+ EP ARFY A++V E +H +
Sbjct: 1105 VVKLYYSFQDHNYLYFVMDYVPGGDLMGLLIRMEILDEPLARFYVAELVQAIESVHRMGF 926
Query: 156 IYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWT------------------------- 190
I+RD+KP+N+LID+ G+I++TDFG G WT
Sbjct: 925 IHRDIKPDNILIDRNGHIKLTDFGLC---TGFRWTHNSKYYQRDGTHARQDSMEVKCQLD 755
Query: 191 -------------------------LCGTPEYLAPEIILSK--GYNKAVDWWALGVLIYE 223
L GTP Y+APE +LS+ GY DWW++GV+++E
Sbjct: 754 EQCQCEILKPLERRRKREQRCLAHSLVGTPNYIAPE-VLSRLGGYTSVCDWWSVGVILFE 578
Query: 224 MAAGYPPFFADQPIQIYEKIVSGK--VRFP--SHFSSDLKDLLRNLLQVDLTKRFGNLKN 279
M G+PPF+A+ P + K+++ K ++ P S+ S KDL+ L R G N
Sbjct: 577 MLVGHPPFYANTPAETQYKVINWKDMLKIPRESNLSQPAKDLILRLC-CGSDDRLG--LN 407
Query: 280 GVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEK 335
G +IK H +FA ++ + RK + P++P + DTSNFD + +++R S +E+
Sbjct: 406 GAGEIKTHMFFAGVNFETL--RKQQPPYVPNIRYATDTSNFDPVDPDKLRNSDSEE 245
>30755
Length = 1137
Score = 170 bits (430), Expect = 8e-43, Method: Compositional matrix adjust.
Identities = 88/218 (40%), Positives = 126/218 (57%), Gaps = 4/218 (1%)
Frame = +2
Query: 124 HLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKR 183
HL F+E RFY A+I+ YLHS +IYRDLK ENLL+D+ G+I+V DFG K
Sbjct: 2 HLSHERIFTEERTRFYGAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCKE 181
Query: 184 --VKGRTW-TLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIY 240
GRT T CGTPEYLAPE++ Y +AVDWW GV++YEM G PF+ ++
Sbjct: 182 DITYGRTTKTFCGTPEYLAPEVLDDNDYGRAVDWWGTGVVMYEMICGRLPFYNRDHDVLF 361
Query: 241 EKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQ 300
I+ V+FP + + + K LL LL D R G ++ V +I+ H +FA+ +W + Q
Sbjct: 362 TLILVEDVKFPRNITDEAKSLLSGLLAKDPRNRLGGGQDDVKEIQAHPFFASINWTDLVQ 541
Query: 301 RKVEAPFIPKFKGPGDTSNFD-DYEEEEIRVSINEKCG 337
+K+ PF P+ DT FD ++ E + ++ + G
Sbjct: 542 KKITPPFKPQVTSDTDTRYFDEEFTGESVELTPPDPTG 655
>18484
Length = 635
Score = 142 bits (359), Expect = 2e-34, Method: Compositional matrix adjust.
Identities = 66/159 (41%), Positives = 100/159 (62%), Gaps = 3/159 (1%)
Frame = +1
Query: 120 EMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFG 179
++ +++ G+F EP A FYAA+I + +LH +IYRDLK +N+++D +G+I++ DFG
Sbjct: 1 DLMYRIQQEGKFKEPVAAFYAAEIAVGLFFLHDQGIIYRDLKLDNVMLDSEGHIKIADFG 180
Query: 180 FAKRV---KGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQP 236
K T T CGTP+Y+APEI+L + Y+K+VDWWA GVL++EM AG PPF +
Sbjct: 181 MCKEGMTGDATTRTFCGTPDYIAPEIVLYQPYSKSVDWWAYGVLLFEMLAGQPPFDGEDE 360
Query: 237 IQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFG 275
+++ I V +P S + L + LL + TKR G
Sbjct: 361 DELFSSITDHNVSYPKAMSREAVSLCKGLLMKNPTKRLG 477
>27405
Length = 532
Score = 124 bits (311), Expect = 5e-29, Method: Compositional matrix adjust.
Identities = 64/177 (36%), Positives = 110/177 (62%), Gaps = 7/177 (3%)
Frame = -3
Query: 46 SFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEH-TLNEKRILQAVNF----PFLVKLE 100
FG V + +TG YAMK LDK+++ K+K E LNE+ +L V+ PF+V +
Sbjct: 530 GFGEVYGCRKADTGKMYAMKCLDKKRI-KMKGGETLALNERIMLSLVSTGEGSPFIVCMT 354
Query: 101 FSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDL 160
++F+ L +++ + GG++ HL + G F+E RFYAA+++L E++HS ++YRDL
Sbjct: 353 YAFQTPEKLCFILDLMNGGDLHYHLSQHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDL 174
Query: 161 KPENLLIDQQGYIQVTDFGFAKRV-KGRTWTLCGTPEYLAPEIIL-SKGYNKAVDWW 215
KP N+L+D+ G+++++D G A K + GT Y+APE+++ + Y+ + DW+
Sbjct: 173 KPANILLDENGHVRISDLGLACDFSKKKPHASVGTHGYMAPEVLMKGQAYDSSADWF 3
>00486
Length = 797
Score = 120 bits (301), Expect = 7e-28, Method: Compositional matrix adjust.
Identities = 54/134 (40%), Positives = 82/134 (61%)
Frame = -2
Query: 188 TWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGK 247
T T CGT EY+APEI+ G+ KAVDWW+LG L+Y+M G PPF A+ + +KI+ GK
Sbjct: 787 THTFCGTIEYMAPEILTRTGHGKAVDWWSLGALMYDMLTGSPPFTAENRKKTIDKILKGK 608
Query: 248 VRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPF 307
+ P + +++ + L++ LL+ + +R G + IK+H++F T+W + R+ E PF
Sbjct: 607 LNLPPYLTNEARGLIKKLLRKNPAERLGGGHDDSGPIKDHQFFRNTNWALLALRRAEPPF 428
Query: 308 IPKFKGPGDTSNFD 321
P DTS FD
Sbjct: 427 RPNVTSDEDTSQFD 386
>31885
Length = 529
Score = 114 bits (286), Expect = 4e-26, Method: Compositional matrix adjust.
Identities = 56/162 (34%), Positives = 96/162 (59%), Gaps = 7/162 (4%)
Frame = -2
Query: 87 ILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLT 146
+L ++ PFLV L ++F+D +L+MV++ GG++ H+++ F E +FY Q+ L
Sbjct: 513 MLTRLDHPFLVNLWYAFQDEEDLFMVVDLFLGGDLRYHMQQEVSFREDCVKFYLCQLALV 334
Query: 147 FEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGR--TWTLCGTPEYLAPEII- 203
+YL S +++RD+KP+N+L+D+QG+ VTDF A +++ + GT Y+APE+
Sbjct: 333 LDYLRSQKIVHRDIKPDNILLDEQGHCHVTDFNIATQLEDDELATSTSGTRPYMAPEVYG 154
Query: 204 ----LSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYE 241
+GY VDWW+LGV ++E+ PF ++E
Sbjct: 153 VAINERRGYGFPVDWWSLGVSLFELLKKRRPFSVHSNTSLHE 28
>15910
Length = 1361
Score = 114 bits (285), Expect = 5e-26, Method: Compositional matrix adjust.
Identities = 57/164 (34%), Positives = 96/164 (58%), Gaps = 9/164 (5%)
Frame = +2
Query: 120 EMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLL---IDQQGYIQVT 176
E+F + G+++E A + I+ +Y+H+ +++RDLKPENLL + +++
Sbjct: 422 ELFDRIVTRGQYTEKDAARAISDILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLA 601
Query: 177 DFGFAKRVKGRTW--TLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFAD 234
DFG ++ ++ T+CGTP Y APE++ Y +VD W++GV+ Y + GY PFFA+
Sbjct: 602 DFGLSRIIEPEVQMSTVCGTPGYCAPEVLKGDKYTPSVDMWSVGVIAYILLCGYEPFFAE 781
Query: 235 QPIQIYEKIVSGKVRFP----SHFSSDLKDLLRNLLQVDLTKRF 274
++Y KI+ G+ +F S S + KD++R LL +D KR
Sbjct: 782 NEFEMYRKIIKGEYKFDEEYWSEISENAKDVVRKLLVIDPKKRL 913
>18921
Length = 697
Score = 110 bits (276), Expect = 6e-25, Method: Compositional matrix adjust.
Identities = 67/203 (33%), Positives = 106/203 (52%), Gaps = 4/203 (1%)
Frame = +2
Query: 34 DQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNF 93
D F+ + LG GS+G V HKETG A+K +V ++ + E I+Q +
Sbjct: 29 DVFDILGKLGEGSYGSVFKSLHKETGQVLAIK-----QVPVDTDLQEIIKEISIMQQCDS 193
Query: 94 PFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLR-RIGRFSEPHARFYAAQIVLTFEYLHS 152
++VK S+ N++L++VMEY G + +R R E + YLHS
Sbjct: 194 KYIVKYYGSYFKNTDLWIVMEYCGAGSVSDIMRLRNKTLVEREIATILYYTLKGLXYLHS 373
Query: 153 LDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVK---GRTWTLCGTPEYLAPEIILSKGYN 209
I+RD+K N+L++ +G+ ++ DFG A ++ + T+ GTP ++APE+I GY+
Sbjct: 374 RRKIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTPYWMAPEVIQEIGYD 553
Query: 210 KAVDWWALGVLIYEMAAGYPPFF 232
D W+LG+ EMA G PP
Sbjct: 554 CVADIWSLGITALEMAEGKPPVM 622
>12721
Length = 821
Score = 110 bits (274), Expect = 1e-24, Method: Compositional matrix adjust.
Identities = 73/255 (28%), Positives = 129/255 (50%), Gaps = 6/255 (2%)
Frame = +1
Query: 25 SPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNE 84
+P LD F +I G GS G V + ++ G A+K +D +K ++ E NE
Sbjct: 70 TPGDPRTFLDDFMKI---GEGSTGIVCIATSRD-GRQMAVKKMDLRK---QQRRELLFNE 228
Query: 85 KRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIV 144
+++ + P +V++ S+ N L++VME++ GG + + + R E +
Sbjct: 229 VVVMRDYHHPNIVEMYNSYLVNDELWVVMEFMEGGAL-TDIVTNNRMDEVQIATVCRACL 405
Query: 145 LTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKG---RTWTLCGTPEYLAPE 201
+LH+ +I+RD+K +++L+ G +++ DFGF +V + +L GTP ++APE
Sbjct: 406 KALAFLHANGVIHRDIKSDSILLSHDGKVKLXDFGFCAQVTQDLQKRKSLVGTPYWMAPE 585
Query: 202 IILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKI---VSGKVRFPSHFSSDL 258
+I Y VD W+LG+++ EM PPFF + P+Q +I K+R S L
Sbjct: 586 VISRLPYGPEVDIWSLGIMVMEMIDAEPPFFNEPPLQAMRRIRDMPPPKLRNTHKISPRL 765
Query: 259 KDLLRNLLQVDLTKR 273
+ + +L D +R
Sbjct: 766 QGFIDRMLVRDPHQR 810
>09606
Length = 1300
Score = 102 bits (253), Expect = 3e-22, Method: Compositional matrix adjust.
Identities = 69/275 (25%), Positives = 123/275 (44%), Gaps = 33/275 (12%)
Frame = -3
Query: 33 LDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVN 92
++ F + LG G + + K T N A+ ++K K ++ N R+ ++
Sbjct: 1118 MENFVLYEELGKGEHSIIYKGRRKGTINFVAIHCIEKCKRPEVT------NTVRMTHDIS 957
Query: 93 FPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHS 152
P +V+ ++ +++L++V+E GG + L + E R + +V Y+HS
Sbjct: 956 HPNVVQFHEWYETSNHLWLVVELCTGGSLADILAQDHHLPETSIRDFGIHLVTGLHYIHS 777
Query: 153 LDLIYRDLKPENLLIDQQGYIQVTDFGFAK-------------RVKGRTWTL-------- 191
L +++ DL+P +L+D G ++ DFG +K G W +
Sbjct: 776 LGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQWNIQSAEEMMK 597
Query: 192 ----CGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGK 247
G+P Y+APE+ + D WALG + YEM +G+PPF + +K+++ +
Sbjct: 596 QVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSGHPPFLGETYDITKDKVLNKE 417
Query: 248 VRFPSHFSSDLK--------DLLRNLLQVDLTKRF 274
P S L +LL +LLQ D T+R
Sbjct: 416 FPLPKVKGSRLSAKPSPEFLNLLESLLQKDSTRRL 312
>26560
Length = 398
Score = 101 bits (252), Expect = 4e-22, Method: Compositional matrix adjust.
Identities = 43/114 (37%), Positives = 76/114 (66%), Gaps = 2/114 (1%)
Frame = -1
Query: 120 EMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFG 179
++ HL + G F+E RFYAA+++L E++HS ++YRDLKP N+L+D+ G+++++D G
Sbjct: 398 DLHYHLSQHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLG 219
Query: 180 FAKRV-KGRTWTLCGTPEYLAPEIIL-SKGYNKAVDWWALGVLIYEMAAGYPPF 231
A K R GT Y+APE+++ + Y+ + DW++ G ++Y++ G+ PF
Sbjct: 218 LACDFSKKRPHASVGTHGYMAPEVLMKGQSYDSSADWFSFGCMLYKLLKGHSPF 57
>01707
Length = 757
Score = 100 bits (248), Expect = 1e-21, Method: Compositional matrix adjust.
Identities = 64/201 (31%), Positives = 109/201 (54%), Gaps = 6/201 (2%)
Frame = +1
Query: 33 LDQFERIKTLGTGSFGRVMLVKHKETGNHYAMK-ILDKQKVVKLKQIEHTLNEKRILQAV 91
++++E+I +G GS+G V ++KET A+K ++ + +K+I + E R+L+ +
Sbjct: 61 MEKYEKIGKIGEGSYGVVFKCRNKETSQLVAIKKFVESEDDPLIKKI--AMREIRMLKQL 234
Query: 92 NFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGR-FSEPHARFYAAQIVLTFEYL 150
P LV+L F+ L++V +YV + + L R R EP + Q +L +
Sbjct: 235 KHPNLVRLIEVFRRKKRLHLVFDYV-DHTLLNELDRYPRGLPEPMVKRIIYQTLLAVNFC 411
Query: 151 HSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKG---RTWTLCGTPEYLAPEIILSKG 207
H + I+RD+KPEN+LI +QG +++ DFGFA+ + G T Y APE+++
Sbjct: 412 HQYNTIHRDVKPENILITRQGQVKLCDFGFARILTGPGDEYTDYVATRWYRAPELLVGDT 591
Query: 208 -YNKAVDWWALGVLIYEMAAG 227
Y VD WA+G + E+ G
Sbjct: 592 QYGPPVDVWAIGCVFAELLTG 654
>00300
Length = 2318
Score = 99.0 bits (245), Expect = 3e-21, Method: Compositional matrix adjust.
Identities = 73/250 (29%), Positives = 118/250 (47%), Gaps = 11/250 (4%)
Frame = -1
Query: 35 QFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFP 94
+++R +G G FG+V + TG A+K + Q L+Q+ +E +I + +
Sbjct: 1655 RWQRGNKIGEGQFGKVYTAVNMSTGELMALKEMKFQPN-DLQQLREMCDEIKIFEGIQHE 1479
Query: 95 FLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLD 154
LVK + M MEY G + ++G E R Y +IVL +LH
Sbjct: 1478 NLVKYYGVEVHKDEMLMFMEYCDTGTI-EEAAKMG-LPEYLIRRYTREIVLAVNHLHENS 1305
Query: 155 LIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRT------WTLCGTPEYLAPEIILSK-- 206
+++RD+K N+ + G++++ DFG + ++K T L GT Y+APE+
Sbjct: 1304 IVHRDIKGANIFLTSNGHVKLGDFGCSVKLKSHTTMPGEFHNLVGTTAYMAPEVFTQNDQ 1125
Query: 207 -GYNKAVDWWALGVLIYEMAAGYPPFF-ADQPIQIYEKIVSG-KVRFPSHFSSDLKDLLR 263
GY +A D W+LG ++ EMA G P+ D QI K+ G K P S + K L
Sbjct: 1124 GGYGRAADIWSLGCVVIEMATGKRPWHDLDNNYQIMYKVGIGHKPAVPDSLSVEGKHFLD 945
Query: 264 NLLQVDLTKR 273
++ D +R
Sbjct: 944 LIMCHDPAQR 915
>14420
Length = 528
Score = 98.6 bits (244), Expect = 3e-21, Method: Compositional matrix adjust.
Identities = 49/163 (30%), Positives = 88/163 (53%), Gaps = 3/163 (1%)
Frame = +2
Query: 79 EHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARF 138
E +NE +++ P +V S+ L++VME++ GG + + E
Sbjct: 35 ELIINEILVMRENQNPNIVNYLDSYLVGEELWVVMEFLAGGSLTDVVTETC-MDEGQIAA 211
Query: 139 YAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRV---KGRTWTLCGTP 195
+ + E+LH +I+RD+K +N+L+ G +++TDFGF ++ + + T+ GTP
Sbjct: 212 VCRECLQALEFLHENQVIHRDIKSDNILLGMDGSVKLTDFGFCAQLSPEQSKRSTMVGTP 391
Query: 196 EYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQ 238
++APE++ K Y VD W+LGV+ EM G PP+ + P++
Sbjct: 392 YWMAPEVVTRKQYGPTVDIWSLGVMCIEMIEGEPPYLNENPLR 520
>18663
Length = 600
Score = 97.4 bits (241), Expect = 8e-21, Method: Compositional matrix adjust.
Identities = 51/141 (36%), Positives = 76/141 (53%), Gaps = 10/141 (7%)
Frame = +2
Query: 190 TLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPF----FADQPIQ-----IY 240
T CGTP Y+APEI+ + Y +VDWWALGVL+YEM AG PF ++ P Q ++
Sbjct: 5 TFCGTPNYIAPEILRGEDYGFSVDWWALGVLLYEMLAGRSPFDIAGASENPDQNTEDYLF 184
Query: 241 EKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFG-NLKNGVNDIKNHKWFATTDWIAIY 299
+ I+ +R P S +L+ L + R G + ++ DI NH +F DW +
Sbjct: 185 QVILEKTIRIPRSLSVKAASVLKGFLNKNPADRLGCHRESAFMDIVNHPFFKVIDWEMLE 364
Query: 300 QRKVEAPFIPKFKGPGDTSNF 320
+++V PF P+ D +NF
Sbjct: 365 RKQVSPPFKPRLDSDRDLANF 427
>13592
Length = 980
Score = 92.8 bits (229), Expect = 2e-19, Method: Compositional matrix adjust.
Identities = 68/249 (27%), Positives = 118/249 (47%), Gaps = 12/249 (4%)
Frame = +2
Query: 42 LGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEF 101
+G G FG+V + TG AMK + Q + + +++ E +IL+ + LV+
Sbjct: 8 IGQGRFGKVYTAVNNNTGELMAMKEIAIQPG-ETRALKNVAEELKILEGIKHKNLVRYYG 184
Query: 102 SFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLK 161
L + ME G + S + G E +R + AQ++ LH +++RD+K
Sbjct: 185 IEVHREELLIFMELCSEGTLESLVELTGGLPEALSRRFTAQLLSGVAELHKHGIVHRDIK 364
Query: 162 PENL-LIDQQGYIQVTDFGFAKRVKGRTWT------LCGTPEYLAPEIIL---SKGYNKA 211
N+ L+D +++ DFG A +++ T GT Y+APE+ S G+ +
Sbjct: 365 TANIFLVDGSNSLKLGDFGSAVKIQAHTTVPGELQGYVGTQAYMAPEVFTKTNSDGHGRL 544
Query: 212 VDWWALGVLIYEMAAGYPPFFA-DQPIQIYEKIVSG-KVRFPSHFSSDLKDLLRNLLQVD 269
D W++G ++ EMA+G P+ D QI K+ G K + P S + D + + LQ D
Sbjct: 545 ADIWSVGCVVVEMASGKRPWAQFDSNFQIMFKVGMGEKPQAPESLSQEGHDFIDHCLQHD 724
Query: 270 LTKRFGNLK 278
+R ++
Sbjct: 725 PKQRLSAIE 751
>26156
Length = 479
Score = 82.0 bits (201), Expect(2) = 2e-19, Method: Compositional matrix adjust.
Identities = 43/112 (38%), Positives = 67/112 (59%), Gaps = 1/112 (0%)
Frame = -1
Query: 28 QNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRI 87
+N L F ++ +G GS+ +V+ V+HK T YAMK++ K+ V + I+ EK +
Sbjct: 407 RNKLGLTDFLLLRVIGRGSYAKVLQVEHKRTKRIYAMKVIKKELVNDDEDIDWVQTEKHV 228
Query: 88 LQ-AVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARF 138
+ A N+PFLV L F+ S L+ V+E+V GG++ H++R R E HARF
Sbjct: 227 FETATNYPFLVGLHSCFQSESRLFFVIEFVNGGDLMFHMQRQRRLPEEHARF 72
Score = 31.2 bits (69), Expect(2) = 2e-19, Method: Compositional matrix adjust.
Identities = 12/24 (50%), Positives = 17/24 (70%)
Frame = -3
Query: 138 FYAAQIVLTFEYLHSLDLIYRDLK 161
FY+A+I L +LH ++YRDLK
Sbjct: 75 FYSAEICLALNFLHKRGIVYRDLK 4
>01392
Length = 1806
Score = 91.7 bits (226), Expect = 4e-19, Method: Compositional matrix adjust.
Identities = 60/199 (30%), Positives = 88/199 (44%), Gaps = 35/199 (17%)
Frame = -1
Query: 129 GRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLL---IDQQGYIQVTDFGFAKRVK 185
G E A I ++LHS + +RDLKPEN+L +D +++ DF A +
Sbjct: 1806 GHLCEREASLVVRHIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGIS 1627
Query: 186 G--------RTWTLCGTPEYLAPEIIL-----SKGYNKAVDWWALGVLIYEMAAGYPPFF 232
T G+ EY+APE++ S Y+K D W+LG+++Y M GYPPF+
Sbjct: 1626 CDGDGTKTPELLTPVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILYIMLCGYPPFY 1447
Query: 233 A---------------DQPIQIYEKIVSGKVRFPSH----FSSDLKDLLRNLLQVDLTKR 273
D ++ I G +FPS SS KDL+R+LL + KR
Sbjct: 1446 GQCGEDCGWNRGEACHDCQDMLFNSIQDGHYKFPSQEWTSISSSAKDLIRHLLVREPRKR 1267
Query: 274 FGNLKNGVNDIKNHKWFAT 292
+ D+ H W T
Sbjct: 1266 Y-----SAADVLKHPWICT 1225
>17975
Length = 449
Score = 85.9 bits (211), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 48/137 (35%), Positives = 80/137 (58%), Gaps = 2/137 (1%)
Frame = +3
Query: 47 FGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDN 106
F V L +H TG A+K++DK K+ ++ + H E R ++ V P +V+L
Sbjct: 6 FAVVKLARHVFTGEKVAVKVIDKTKLDEVSR-SHLFQEVRCMKLVQHPNVVRLYEVIDTQ 182
Query: 107 SNLYMVMEYVPGGEMFSH-LRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENL 165
+ LY+++E GG+M+ + +R G E A+ Y QIV Y H L +++RDLKPEN+
Sbjct: 183 TKLYLILELGDGGDMYDYIMRHSGGLEEKLAKRYFRQIVEAISYCHKLHVVHRDLKPENV 362
Query: 166 L-IDQQGYIQVTDFGFA 181
+ ++ G +++TDFGF+
Sbjct: 363 VFFEKPGLVKLTDFGFS 413
>13066
Length = 551
Score = 84.0 bits (206), Expect = 9e-17, Method: Compositional matrix adjust.
Identities = 48/164 (29%), Positives = 85/164 (51%), Gaps = 8/164 (4%)
Frame = +3
Query: 63 AMKILDKQKVVKLKQIEHTL-NEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEM 121
A KI+DK+K + +E E +L ++ P+++++ + ++ M + G++
Sbjct: 63 ACKIIDKEKA-PVDFVEKFFPRELDLLTKLDHPYIIQIHSILQRXPKNFIFMRFAERGDL 239
Query: 122 FSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFA 181
++++ +G E A+ + Q+ YLHS D+ +RDLK EN+L+ +++ DFGFA
Sbjct: 240 LTYIQEVGFVKEKQAKIWFYQMTTALNYLHSYDVAHRDLKCENILLSSHFNVKLADFGFA 419
Query: 182 KRV------KGRTWTLCGTPEYLAPEIILSKGYN-KAVDWWALG 218
K + T CG+ Y APEI+ Y K D W+LG
Sbjct: 420 CACITESGEKYMSRTYCGSAAYAAPEIVYGAPYAPKVADAWSLG 551
>06405
Length = 1965
Score = 83.6 bits (205), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 70/240 (29%), Positives = 110/240 (45%), Gaps = 8/240 (3%)
Frame = +1
Query: 42 LGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEF 101
LG G +G V K A+K L K+ + L L E I++ + P LV+L
Sbjct: 283 LGGGQYGDVYEAMWKRYNKIVAVKTL-KEDTMALNDF---LEEAAIMKEMKHPNLVQLLG 450
Query: 102 SFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSE-PHARFY-AAQIVLTFEYLHSLDLIYRD 159
Y+V E++P G + +LR R P A Y A QI YL + + I+RD
Sbjct: 451 VCTREPPFYIVTEFMPHGNLLDYLRSSTREENGPTALMYMATQIASGMAYLETKNFIHRD 630
Query: 160 LKPENLLIDQQGYIQVTDFGFAKRVKGRTWTL-CGTP---EYLAPEIILSKGYNKAVDWW 215
L N L+ ++V DFG A+ +K T+T G ++ APE + ++ D W
Sbjct: 631 LAARNCLVADSNMVKVADFGLARLMKDDTYTAHIGAKFPIKWTAPEGLAFNRFSTRSDIW 810
Query: 216 ALGVLIYEMAA-GYPPFFADQPIQIYEKIVSG-KVRFPSHFSSDLKDLLRNLLQVDLTKR 273
A GVL++E+A G P+ + ++Y + G ++ P +D+ L+ Q D R
Sbjct: 811 AFGVLLWELATYGMSPYPGVELTEVYHLLERGYRMERPPGTPADVYILMLKCWQWDPKDR 990
>01060
Length = 1800
Score = 81.6 bits (200), Expect = 4e-16, Method: Compositional matrix adjust.
Identities = 67/234 (28%), Positives = 110/234 (47%), Gaps = 21/234 (8%)
Frame = +1
Query: 31 AHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIE-----HTLNEK 85
+ L F++I G G++G V +H+ TG AMK ++L+ E + E
Sbjct: 73 SDLTDFQKI---GEGTYGVVYKCRHRATGRKLAMK------KIRLRGSEDGVPSSAIREI 225
Query: 86 RILQAVNFPFLVKLEFSFKDNSNLYMVMEYV-----------PGGEMFSHLRRIGRFSEP 134
+L+ + +V LE ++ L++V E++ P G + RR+
Sbjct: 226 AMLRELRHTNIVCLEDVIMEDERLFLVFEFLSMDLKMYIDKFPEGVVLD--RRL------ 381
Query: 135 HARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKR----VKGRTWT 190
+ Y QIV + H +++RDLKP+NLLI+ G I++ DFG A+ V+ T
Sbjct: 382 -VKSYVFQIVTGIXFCHQRRIVHRDLKPQNLLINHTGAIKIADFGMARTFALPVRAYTHE 558
Query: 191 LCGTPEYLAPEIIL-SKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKI 243
+ T Y APEI++ + Y+ VD W++G + +M P F D I KI
Sbjct: 559 VV-TLWYRAPEILMGASKYSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKI 717
>21079
Length = 878
Score = 80.5 bits (197), Expect = 9e-16, Method: Compositional matrix adjust.
Identities = 47/142 (33%), Positives = 75/142 (52%), Gaps = 5/142 (3%)
Frame = +1
Query: 94 PFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIG-RFSEPHARFYAAQIVLTFEYLHS 152
P L+ L +F+ + +VME+V GE+F + R +E + QI Y+H+
Sbjct: 4 PKLLMLWDAFEAPRTMVLVMEFVGAGELFERVIRDDFVLTERDCVHFVRQICSGVGYMHT 183
Query: 153 LDLIYRDLKPENLLI--DQQGYIQVTDFGFAKRVK--GRTWTLCGTPEYLAPEIILSKGY 208
+++ DLKPEN+L D I++ DFG A+ K L GTPE++APE++
Sbjct: 184 QSILHLDLKPENVLCVSDNSNQIKIIDFGLARFYKPGDSLQVLFGTPEFIAPEVVNYDEI 363
Query: 209 NKAVDWWALGVLIYEMAAGYPP 230
N D W++GV+ Y + +G P
Sbjct: 364 NFTTDMWSIGVICYILLSGLSP 429
>21433
Length = 590
Score = 78.2 bits (191), Expect = 5e-15, Method: Compositional matrix adjust.
Identities = 46/130 (35%), Positives = 69/130 (53%), Gaps = 1/130 (0%)
Frame = +2
Query: 139 YAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRV-KGRTWTLCGTPEY 197
Y Q+ EY H +I+RD+KPENLL+ +G +++ DFG++ R T+CGT +Y
Sbjct: 182 YIYQLSSALEYCHYRKVIHRDIKPENLLLGLKGDLKIADFGWSVHAPSSRRTTMCGTLDY 361
Query: 198 LAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSD 257
L PE++ K +++ VD W+LGVL YE G PP PS +
Sbjct: 362 LPPEMVEGKTHDENVDLWSLGVLCYEFLVGTPPLRPSPTRPPTPASPRWTSGSPSIVTPG 541
Query: 258 LKDLLRNLLQ 267
+DL+ LL+
Sbjct: 542 ARDLISKLLR 571
>17722
Length = 680
Score = 75.5 bits (184), Expect = 3e-14, Method: Compositional matrix adjust.
Identities = 37/106 (34%), Positives = 56/106 (52%)
Frame = -3
Query: 212 VDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLT 271
VDWW GV++YEM G PF+ ++E I+ V+FP + S + K LL LL +
Sbjct: 678 VDWWGTGVVMYEMMCGRLPFYNRDHDVLFELILLQNVKFPRNLSEEAKTLLSGLLAKNPK 499
Query: 272 KRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDT 317
+R G + V +IK H +F +W + +K+ P+ P K DT
Sbjct: 498 RRLGGSEADVTEIKTHPFFQCINWDDLAAKKITPPWKPDVKSSWDT 361
>01756
Length = 1858
Score = 74.3 bits (181), Expect = 7e-14, Method: Compositional matrix adjust.
Identities = 55/212 (25%), Positives = 104/212 (49%), Gaps = 17/212 (8%)
Frame = -3
Query: 35 QFERIKTLGTGSFGRVMLVKHKETGNHYAMK--ILDKQK----VVKLKQIE--HTLNEKR 86
++E++ +G G+FG V + K+T AMK ++D +K + L++I+ LN +
Sbjct: 1739 KYEKLAKIGQGTFGEVFKARCKKTKQVVAMKKVLMDNEKEGFPITALREIKILQLLNHEN 1560
Query: 87 ILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPG--GEMFSHLRRIGRFSEPHARFYAAQIV 144
++ + K + + S Y+V E+ + S++ + F+ P + Q++
Sbjct: 1559 VVDLIEI-CSTKATSANRYKSMFYLVFEFCEHDLAGLLSNMSVV--FNLPEIKEVMKQLM 1389
Query: 145 LTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAK------RVKGRTWTLCGTPEYL 198
Y+H +++RD+K N+LI +QG +++ DFG A+ R R T Y
Sbjct: 1388 NGLYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYR 1209
Query: 199 APEIILS-KGYNKAVDWWALGVLIYEMAAGYP 229
PE++L + Y+ A+D W G ++ EM P
Sbjct: 1208 PPELLLGDRNYSTAIDQWGAGCIMAEMWTRNP 1113
>00392
Length = 668
Score = 72.4 bits (176), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 50/177 (28%), Positives = 99/177 (55%), Gaps = 14/177 (7%)
Frame = +3
Query: 84 EKRILQAVNFPFLVKL-----EFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARF 138
E +L+ + P +V+ E + ++ + +V E + G + ++L+R F +P+ +
Sbjct: 81 EAEMLKELQHPNIVRFFDYWEEHNHRNRKVIILVTELMTSGTLKTYLKR---FKKPNVKI 251
Query: 139 ---YAAQIVLTFEYLHSLD--LIYRDLKPENLLID-QQGYIQVTDFGFAKRVKGRTW--T 190
+ Q++ +LH+ +I+RDLK +N+ I G +++ D G A +K +++ +
Sbjct: 252 LKNWCRQVLKGLYFLHTRTPPVIHRDLKCDNIFITGPTGSVKIGDLGLAT-LKNQSFAKS 428
Query: 191 LCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAG-YPPFFADQPIQIYEKIVSG 246
+ GTPE++APE+ + Y++AVD +A G+ + EMA+ YP QIY+++ SG
Sbjct: 429 VIGTPEFMAPEM-YEEHYDEAVDVYAFGMCMLEMASSEYPYSECSNAAQIYKRVTSG 596
>27546
Length = 426
Score = 70.9 bits (172), Expect = 6e-13, Method: Compositional matrix adjust.
Identities = 30/102 (29%), Positives = 59/102 (57%)
Frame = -1
Query: 84 EKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQI 143
E IL ++ P ++++ + +++ M Y G+M SH+++ G E + + Q+
Sbjct: 330 ELEILTRLDHPNIIQIHSILQRGPKIFIFMRYAEKGDMLSHIKKTGPIDEAQTKVWFFQM 151
Query: 144 VLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVK 185
+YLHS D+ +RDLK EN+L+ ++ +++ DFGFA+ +
Sbjct: 150 AKALQYLHSHDIAHRDLKCENILLSKRLNVKIADFGFARYCR 25
>09007
Length = 1440
Score = 70.5 bits (171), Expect = 9e-13, Method: Compositional matrix adjust.
Identities = 59/220 (26%), Positives = 102/220 (46%), Gaps = 16/220 (7%)
Frame = -1
Query: 40 KTLGTGSFGRV-MLVKHKETGN--HYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFL 96
K+LG G FG V + E+G A+K L K K+ K Q L E I+Q ++ +
Sbjct: 861 KSLGQGHFGTVRQAIWTAESGEKVQVAVKCLSKDKIHKDGQ--EFLKETAIMQMLDHENI 688
Query: 97 VKLEFSFKDN-SNLYMVMEYVPGGEMFSHLRRIGR---FSEPHARFYAAQIVLTFEYLHS 152
V++ DN +++ +V E P + ++ + FS P ++ Q+ YL S
Sbjct: 687 VRVYGVVMDNGADIMLVTELAPMRSLLECVKEVSARVDFSVPRLCDFSQQVCDGMSYLES 508
Query: 153 LDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKG--------RTWTLCGTPEYLAPEIIL 204
L++RDL N+L+ + ++++D G + + +T L + APE
Sbjct: 507 KRLVHRDLAARNILLFSKSKVKISDVGVSGALGAGKEYYQSQQTIHLQNAVAWCAPESFR 328
Query: 205 SKGYNKAVDWWALGVLIYE-MAAGYPPFFADQPIQIYEKI 243
+ ++ A D WA GVL++E G+ P+ QI E +
Sbjct: 327 NLCFSSASDVWAFGVLLWEFFTHGFQPWAGLNGQQIMEAV 208
>19094
Length = 898
Score = 69.7 bits (169), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 33/82 (40%), Positives = 52/82 (63%), Gaps = 3/82 (3%)
Frame = +1
Query: 149 YLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVK---GRTWTLCGTPEYLAPEIILS 205
YLHS I+RD+K N+L++ +G+ ++ DFG A ++ + T+ GTP ++APE+I
Sbjct: 103 YLHSRRKIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTPYWMAPEVIQE 282
Query: 206 KGYNKAVDWWALGVLIYEMAAG 227
GY+ D W+LG+ EMA G
Sbjct: 283 IGYDCVADIWSLGITALEMAEG 348
>25019
Length = 730
Score = 68.9 bits (167), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 31/59 (52%), Positives = 43/59 (72%), Gaps = 3/59 (5%)
Frame = +3
Query: 163 ENLLIDQQGYIQVTDFGFAKR-VKGR--TWTLCGTPEYLAPEIILSKGYNKAVDWWALG 218
EN+L+D+ G++++TDFG K + G T T CGT EY+APEI+ G+ KAVDWW+LG
Sbjct: 261 ENVLLDKDGHVKLTDFGLCKEAITGTRVTHTFCGTIEYMAPEILTRTGHGKAVDWWSLG 437
Score = 48.1 bits (113), Expect = 5e-06, Method: Compositional matrix adjust.
Identities = 23/74 (31%), Positives = 41/74 (55%), Gaps = 4/74 (5%)
Frame = +1
Query: 206 KGYNKAVDW----WALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDL 261
+G A W W G L+Y+M G PPF A+ + +KI+ GK+ P + +++ + L
Sbjct: 394 RGQGTARRWTGGVW--GALMYDMLTGSPPFTAENRKKTIDKILKGKLNLPPYLTNEARGL 567
Query: 262 LRNLLQVDLTKRFG 275
++ LL+ + +R G
Sbjct: 568 IKKLLRKNPAERLG 609
>01718
Length = 959
Score = 68.6 bits (166), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 58/212 (27%), Positives = 99/212 (46%), Gaps = 15/212 (7%)
Frame = +3
Query: 33 LDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVN 92
LD F + +G G F V V H+ TG A+K+ + L E ++L +
Sbjct: 147 LDDF-ICEKIGAGFFSEVFKVTHRITGQVMALKM-----NTMTSNRHNMLREVQLLNRLQ 308
Query: 93 FPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTF----- 147
+++ L+ + EY+P G + L + + + +I LT
Sbjct: 309 HANILRFMGVCVHEGQLHALTEYIPSGNLEQLLEK-----KDEELPWTQRIQLTLGLARG 473
Query: 148 -EYLHSLDLIYRDLKPENLLI---DQQGYIQV-TDFGFAKRV-----KGRTWTLCGTPEY 197
+YLHS I+RDL +N+LI D GY V DFG A ++ K + T+ G+P +
Sbjct: 474 LDYLHSTRFIHRDLTSKNILIRREDNHGYHAVIADFGLATKIPDPLDKEKLPTV-GSPYW 650
Query: 198 LAPEIILSKGYNKAVDWWALGVLIYEMAAGYP 229
+APE++ YN+ D +++G+++ E+ A P
Sbjct: 651 MAPEVLNGHFYNERADLFSVGIIMCEITARIP 746
>19761
Length = 473
Score = 68.2 bits (165), Expect = 4e-12, Method: Compositional matrix adjust.
Identities = 34/128 (26%), Positives = 68/128 (53%), Gaps = 3/128 (2%)
Frame = -3
Query: 145 LTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGR---TWTLCGTPEYLAPE 201
L + + H+ +++RDLKP+N+ + ++G +++ D G A+++ G + GT YL+PE
Sbjct: 384 LNYMHTHTPVILHRDLKPQNIYVTEKGDVRLGDLGLARKLTGPADFATSQVGTIMYLSPE 205
Query: 202 IILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDL 261
I+ + YN D W+LG + Y++ + + + K+ P H+S + +D
Sbjct: 204 ILSQQPYNSKSDIWSLGCVFYDITGKKGSDEMGVMFLLVQVMGGRKLPLPDHYSQEFRDT 25
Query: 262 LRNLLQVD 269
+ +L D
Sbjct: 24 ISRMLTKD 1
>26711
Length = 405
Score = 67.8 bits (164), Expect = 6e-12, Method: Compositional matrix adjust.
Identities = 41/130 (31%), Positives = 70/130 (53%), Gaps = 9/130 (6%)
Frame = -2
Query: 142 QIVLTFEYLHSLDLIYRDLKPENLLI--DQQGYIQVTDFGFAKRV--KGRTWTLCGTPEY 197
Q++ +++H+ +++ DLKP NLL+ D+ +Q+ DFG A+++ T+ GTP +
Sbjct: 392 QVLDILQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARKLYPPQETFLNHGTPGF 213
Query: 198 LAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFP-----S 252
+PE + K + A D W +GVL Y + +G PF AD + +K + F S
Sbjct: 212 TSPEALDVKPISTASDVWGVGVLAYILLSGQSPFQADSATESLKKTQTCDWSFDVCPSFS 33
Query: 253 HFSSDLKDLL 262
+ S D KD +
Sbjct: 32 NMSQDAKDFI 3
>11185
Length = 473
Score = 65.5 bits (158), Expect = 3e-11, Method: Compositional matrix adjust.
Identities = 43/163 (26%), Positives = 67/163 (41%), Gaps = 25/163 (15%)
Frame = +1
Query: 137 RFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAK-------------R 183
R + +V Y+HSL +++ DL+P +L+D G ++ DFG +K
Sbjct: 10 RDFGIHLVTGLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFA 189
Query: 184 VKGRTWTL------------CGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPF 231
G W + G+P Y+APE+ + D WALG + YEM +G
Sbjct: 190 EAGDQWNIQSAEEMMKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSG---- 357
Query: 232 FADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRF 274
R + S + +LL +LLQ D T+R
Sbjct: 358 ----------------SRLSAKPSPEFLNLLESLLQKDSTRRL 438
>38560
Length = 479
Score = 65.1 bits (157), Expect = 3e-11, Method: Compositional matrix adjust.
Identities = 38/131 (29%), Positives = 60/131 (45%), Gaps = 6/131 (4%)
Frame = -3
Query: 190 TLCGTPEYLAPEIILSKGY-NKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKV 248
T CG+P Y APE+I Y D W++GVL+Y + GY PF ++ + +K K
Sbjct: 408 TCCGSPAYAAPELISGLEYLGSEADIWSMGVLLYALLCGYLPFDDEKXSHL*QKNQKRKD 229
Query: 249 RFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWF-----ATTDWIAIYQRKV 303
P S D LL +LQ D + R + + +H W +W + Y+R +
Sbjct: 228 EVPEWLSEDTTKLLEGMLQTDPSHRI-----TIRRLLDHHWLNQGFNVPVEWASKYKRTL 64
Query: 304 EAPFIPKFKGP 314
+ + + GP
Sbjct: 63 DEDCLTEAGGP 31
>29581
Length = 1278
Score = 64.3 bits (155), Expect = 7e-11, Method: Compositional matrix adjust.
Identities = 45/148 (30%), Positives = 75/148 (50%), Gaps = 7/148 (4%)
Frame = -2
Query: 104 KDNSNLYMVMEYVPGGEMFSHLRRI-GRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKP 162
K +L++VMEY ++ S L + FSE + Q++ YLH +I+RDLK
Sbjct: 1139 KSLDSLFLVMEYC-EQDLASLLDNMPAPFSESQVKCIVLQLLKGLRYLHEAFIIHRDLKV 963
Query: 163 ENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPE-----YLAPEIIL-SKGYNKAVDWWA 216
NLL+ +G +++ DFG A+ + TP+ Y APE++ SK ++ A+D W+
Sbjct: 962 SNLLMTDKGCVKIADFGLARNYGKPQKPM--TPKVVTLWYRAPELLFGSKTHSTAIDMWS 789
Query: 217 LGVLIYEMAAGYPPFFADQPIQIYEKIV 244
G ++ E+ P +Q E I+
Sbjct: 788 AGCILGELLGHKPLMPGRSDLQQIELIM 705
>13212
Length = 1067
Score = 63.9 bits (154), Expect = 8e-11, Method: Compositional matrix adjust.
Identities = 34/121 (28%), Positives = 64/121 (52%), Gaps = 8/121 (6%)
Frame = -1
Query: 131 FSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKR---VKGR 187
+E + ++ + ++LH +I+RD+K N+L+ G +++ DFG + + + +
Sbjct: 989 MTEAQICYVCHEMCMALDFLHRHHVIHRDIKAGNVLLTIDGEVKLADFGVSAKNTQTQQK 810
Query: 188 TWTLCGTPEYLAPEIILSKG-----YNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEK 242
T GTP ++APE++L + Y+ D W+LGV + E A PP P+++ K
Sbjct: 809 RDTFIGTPYWMAPEVVLCETLKDTPYDFKADIWSLGVTLIEFAQIEPPNKEMHPMRVLIK 630
Query: 243 I 243
I
Sbjct: 629 I 627
>28638
Length = 1458
Score = 63.9 bits (154), Expect = 9e-11, Method: Compositional matrix adjust.
Identities = 32/100 (32%), Positives = 59/100 (59%), Gaps = 4/100 (4%)
Frame = -1
Query: 136 ARFYAAQIVLTFEYLHS--LDLIYRDLKPENLLI--DQQGYIQVTDFGFAKRVKGRTWTL 191
R +A Q+ +L + +++I+ DLKPEN+L+ ++ I++ DFG + ++ R +
Sbjct: 831 TRKFAQQLCTALLFLATPEMNIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQY 652
Query: 192 CGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPF 231
+ Y +PE++L Y+ A+D W+LG ++ EM G PP
Sbjct: 651 IQSRFYRSPEVLLGVPYDLAIDMWSLGCILVEMHTGEPPL 532
>28157
Length = 400
Score = 63.2 bits (152), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 44/124 (35%), Positives = 68/124 (54%), Gaps = 13/124 (10%)
Frame = +3
Query: 71 KVVKLKQIEHTLNEKRILQA------VNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSH 124
K V +K+IE +K +Q V+ P +V L + +D+ + +VMEY GG +++
Sbjct: 3 KDVAVKRIESEQEKKSFMQELKQLSRVSHPNIVCLYGACRDHP-VCLVMEYAEGGSLYNV 179
Query: 125 LRRIG---RFSEPHARFYAAQIVLTFEYLHSLD---LIYRDLKPENLLIDQQGY-IQVTD 177
L G +++ HA + Q L EYLH + LI+RDLKP NLL+ Q G +++ D
Sbjct: 180 LHGSGPQPQYTAAHAMNWLLQCALGVEYLHGMKPKALIHRDLKPPNLLLIQCGTKLKICD 359
Query: 178 FGFA 181
FG A
Sbjct: 360 FGTA 371
>14126
Length = 1265
Score = 62.0 bits (149), Expect = 3e-10, Method: Compositional matrix adjust.
Identities = 50/204 (24%), Positives = 99/204 (48%), Gaps = 14/204 (6%)
Frame = +3
Query: 35 QFERIKTLGTGSFGRVMLVKH-KETGNHYAMKIL---DKQKVVKLKQIEHTLNEKRILQA 90
++E + +G G++G V + + G AMK + + ++ + + I K+ L+
Sbjct: 192 KYEEVAVIGNGAYGTVYKARDLRNQGEFVAMKRIRLNNTEEGMPMMAIREISMLKQ-LEQ 368
Query: 91 VNFPFLVKLEFSFKDNS------NLYMVMEYVPGGEMFSHLRRIGR--FSEPHARFYAAQ 142
P +V+L N+ L +V EY+ ++ ++L + + Q
Sbjct: 369 YEHPNVVRL-LDVSHNTITDREIRLNLVFEYIEH-DLATYLAKCPSPGLGPDRIKDLMLQ 542
Query: 143 IVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAK--RVKGRTWTLCGTPEYLAP 200
++ ++LHS +++RDLKP+NLLI + G +++ DFG A+ T+ T Y +P
Sbjct: 543 LLNGVDFLHSNRIVHRDLKPQNLLISKDGRLKLADFGLARIYSFHMALTTVVVTLWYRSP 722
Query: 201 EIILSKGYNKAVDWWALGVLIYEM 224
E+++ Y +VD W+ G + E+
Sbjct: 723 EVLMQAEYGTSVDIWSCGCIFAEL 794
>19301
Length = 712
Score = 60.8 bits (146), Expect = 7e-10, Method: Compositional matrix adjust.
Identities = 46/172 (26%), Positives = 80/172 (46%), Gaps = 3/172 (1%)
Frame = +2
Query: 11 FLAKAKEDFLKK---WESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKIL 67
+ KA LK+ WE P ++ L+ LG+G+ G V L K
Sbjct: 245 IIGKAAAAELKQQDDWEIPFESITDLEW------LGSGAQGAVFLGK----------LCA 376
Query: 68 DKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRR 127
++ V K++ I+ T + R L+ +N P ++ + ++MEY P G+++ LR
Sbjct: 377 EEVAVKKVRDIKET--DIRNLRKLNHPNIISFKGVCTQAPCYCIIMEYCPYGQLYEVLRD 550
Query: 128 IGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFG 179
++ QI YLHS +I+RDLK N+L+ + ++++DFG
Sbjct: 551 GKEIPPALVLDWSKQIASGMNYLHSHKIIHRDLKSPNVLVAKNDVVKISDFG 706
>01966
Length = 1735
Score = 60.8 bits (146), Expect = 7e-10, Method: Compositional matrix adjust.
Identities = 52/188 (27%), Positives = 84/188 (44%), Gaps = 20/188 (10%)
Frame = -1
Query: 53 VKHKETGNHYAMKILDKQKVVKLKQIE-----HTLNEKRILQAVNFPFLVKLEFSFKDNS 107
+H+ TG AMK ++L+ E + E +L+ + +V LE ++
Sbjct: 1654 CRHRATGRKLAMK------KIRLRGSEDGVPSSAIREIAMLRELRHTNIVCLEDVIMEDE 1493
Query: 108 NLYMVMEYV-----------PGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLI 156
L++V E++ P G + RR+ + Y QIV + H ++
Sbjct: 1492 RLFLVFEFLSMDLKMYIDKFPEGVVLD--RRL-------VKSYVFQIVTGINFCHQRRIV 1340
Query: 157 YRDLKPENLLIDQQGYIQVTDFGFAKR----VKGRTWTLCGTPEYLAPEIILSKGYNKAV 212
+RDLKP+NLLI+ G I++ DFG A+ V+ T + T Y APEI++ G
Sbjct: 1339 HRDLKPQNLLINHTGAIKIADFGMARTFALPVRAYTHEVV-TLWYRAPEILM--GPQSTP 1169
Query: 213 DWWALGVL 220
W G L
Sbjct: 1168 PXWTCGAL 1145
>21808
Length = 1011
Score = 58.9 bits (141), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 44/192 (22%), Positives = 85/192 (44%), Gaps = 11/192 (5%)
Frame = +1
Query: 82 LNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSE-PHARFYA 140
L E +I++ + P L++L + ++++ E + G + L+ GR + P
Sbjct: 76 LAEAQIMKKLRHPKLIQLYAVCTQDDPIFIITELMKNGSLLEFLQGKGRVLKLPALIDIG 255
Query: 141 AQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVK--------GRTWTLC 192
AQI YL S + I+RDL N+L+ +++ DFG A+ +K G + +
Sbjct: 256 AQIACGMAYLESQNYIHRDLAARNILVSDNNTVKIADFGLARVIKEDEYEARVGARFPI- 432
Query: 193 GTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAA-GYPPFFADQPIQIYEKIVSG-KVRF 250
++ APE + D W+ G+L+ E G P+ ++ ++ G ++
Sbjct: 433 ---KWTAPEAANYNRFTIKSDVWSFGILLTETVTYGRVPYPGMTNAEVLHQVEHGYRMPC 603
Query: 251 PSHFSSDLKDLL 262
P L D++
Sbjct: 604 PPGCPKPLYDIM 639
>04852
Length = 1462
Score = 58.5 bits (140), Expect = 4e-09, Method: Compositional matrix adjust.
Identities = 41/144 (28%), Positives = 69/144 (47%), Gaps = 8/144 (5%)
Frame = +1
Query: 116 VPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQV 175
PGG + +RR S YA QI E+L S I+RDL N+L+ ++ +++
Sbjct: 298 TPGGHV---IRRKNLLS------YAFQIARGMEFLASRKCIHRDLAARNVLVTEEHVLKI 450
Query: 176 TDFGFA-------KRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEM-AAG 227
DFG + KR GR +++APE + Y D W+ GV+++E+ + G
Sbjct: 451 ADFGLSRTGDYYKKRSGGRL-----PVKWMAPEALFDMRYTTKSDVWSFGVVLWEIFSLG 615
Query: 228 YPPFFADQPIQIYEKIVSGKVRFP 251
P+ + ++Y K++ R P
Sbjct: 616 GMPYASIPNEELYSKLLDDAYRMP 687
>04591
Length = 1117
Score = 57.0 bits (136), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 45/175 (25%), Positives = 86/175 (49%), Gaps = 9/175 (5%)
Frame = -2
Query: 64 MKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPG--GEM 121
++ L+ + VV+L++I HT QA + + S Y++ EY +
Sbjct: 1059 LQQLEHENVVQLQEICHT-------QAGPY---------NRYKSTFYLIFEYCDYDLAGL 928
Query: 122 FSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGF- 180
++LR +FS + +Q++ Y+H+ +++RD+K N+L+ + G +++ DFG
Sbjct: 927 LNNLRV--KFSLADKKNLMSQLLNGLFYIHTKQILHRDIKAANILLTRDGVLKLADFGLS 754
Query: 181 -----AKRVKGRTWTLCGTPEYLAPEIILS-KGYNKAVDWWALGVLIYEMAAGYP 229
+KR+ R TL Y PE++L + Y +D W +G ++ EM + P
Sbjct: 753 RPWVKSKRLTNRVVTLW----YRPPELLLGEREYGPEIDMWGVGCIMAEMWSRKP 601
>32957
Length = 645
Score = 56.6 bits (135), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 24/41 (58%), Positives = 30/41 (73%)
Frame = +3
Query: 186 GRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAA 226
GRT T CGT EY+APE+ K Y K VDWW LG+L++E+ A
Sbjct: 30 GRTRTFCGTREYMAPEVHERKEYGKEVDWWGLGILLHELLA 152
>07940
Length = 1336
Score = 55.1 bits (131), Expect = 5e-08, Method: Compositional matrix adjust.
Identities = 29/91 (31%), Positives = 50/91 (54%), Gaps = 5/91 (5%)
Frame = -3
Query: 139 YAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKG----RTWTLCGT 194
YA Q+ EYL S I+RDL N+L+ ++ +++ DFG + ++ R T
Sbjct: 332 YAYQVARGMEYLASKQCIHRDLAARNVLVAEEYVLKIADFGLTRNLQQFDYYRKTTDGRL 153
Query: 195 P-EYLAPEIILSKGYNKAVDWWALGVLIYEM 224
P +++APE + + Y D W+ GVL++E+
Sbjct: 152 PVKWMAPEALFDRKYTSKSDVWSYGVLLWEI 60
>12786
Length = 460
Score = 54.7 bits (130), Expect = 6e-08, Method: Compositional matrix adjust.
Identities = 34/120 (28%), Positives = 58/120 (48%), Gaps = 25/120 (20%)
Frame = -3
Query: 137 RFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRV-KGRTWTL---- 191
+FY +++ + LH+ +I+ DLKP N ++ G +++ DFG A + + +T L
Sbjct: 401 KFYWREMLRAVKALHNEGVIHSDLKPANFML-VAGNLKLIDFGIANTLQQDKTSVLKDSR 225
Query: 192 CGTPEYLAPEIILSKGYNKA--------------------VDWWALGVLIYEMAAGYPPF 231
GTP Y++PE I++ + A D W+LG ++Y M G PF
Sbjct: 224 VGTPSYMSPEAIMAACDDSADDSMEEDGHRTKPKYKVGVRSDVWSLGCILYNMVYGRTPF 45
>04138
Length = 800
Score = 53.9 bits (128), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 29/88 (32%), Positives = 47/88 (53%), Gaps = 7/88 (7%)
Frame = +1
Query: 149 YLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAK------RVKGRTWTLCGTPEYLAPEI 202
Y+H +++RD+K N+LI +QG +++ DFG A+ R R T Y PE+
Sbjct: 58 YIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRPPEL 237
Query: 203 ILS-KGYNKAVDWWALGVLIYEMAAGYP 229
+L + Y+ A+D W G ++ EM P
Sbjct: 238 LLGDRNYSTAIDQWGAGCIMAEMWTRNP 321
>11780
Length = 1713
Score = 53.5 bits (127), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 39/145 (26%), Positives = 66/145 (45%), Gaps = 2/145 (1%)
Frame = +3
Query: 40 KTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKL 99
+ +G G FG V G + + KQ K + + L E ++ ++ LV+L
Sbjct: 615 EAIGKGDFGDVY------KGMYRGQPVAIKQLKDKDRGEQSFLQEASVMTSLRHDNLVRL 776
Query: 100 EFSFKDNSNLYMVMEYVPGGEMFSHLRRIGR--FSEPHARFYAAQIVLTFEYLHSLDLIY 157
+++V E++ G + +LR GR ++ +A EYL S L++
Sbjct: 777 -IGVVLGETIFLVTEFMGKGNLVEYLRSRGRSVITKKDQINFATDTCAAMEYLESKRLVH 953
Query: 158 RDLKPENLLIDQQGYIQVTDFGFAK 182
RDL N+L+ G +V+DFG AK
Sbjct: 954 RDLAARNVLVHDDGKAKVSDFGLAK 1028
>16708
Length = 1397
Score = 52.0 bits (123), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 41/161 (25%), Positives = 70/161 (43%), Gaps = 14/161 (8%)
Frame = -1
Query: 39 IKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQ---IEHTLNEKRILQAVNFPF 95
++ LG G FG+V Y ++L + LK H+L+E L + F
Sbjct: 1388 LQVLGKGVFGKV-----------YEARLLSTHEKAALKTSILCHHSLDEVEALGRIEGGF 1242
Query: 96 LVKLEFS-------FKDNSNLYMVMEYVPGGEMFSHLRRIG---RFSEPH-ARFYAAQIV 144
+ F F + L E P +++H + R+S P A Q V
Sbjct: 1241 YLAQMFGAWVTCLPFPKMNILLHFYEMGPLCNVYAHYKNKEMPIRWSNPAMVCCIAGQXV 1062
Query: 145 LTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVK 185
E++H L +++ D+K +N+L+D G ++TD+G A+ K
Sbjct: 1061 CALEHIHELGVVHMDVKADNVLVDAHGNCKLTDYGIAQLYK 939
>03508
Length = 1463
Score = 51.6 bits (122), Expect = 5e-07, Method: Compositional matrix adjust.
Identities = 30/113 (26%), Positives = 62/113 (54%), Gaps = 4/113 (3%)
Frame = +1
Query: 131 FSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQG-YIQVTDFGFAKRVK-GRT 188
F++ RFY +++ ++ HS+ +++RD+KP N++ID + +++ D+G A+ G
Sbjct: 862 FTDYDIRFYLYELMKALDFCHSMGIMHRDVKPHNVMIDHENKKLRLIDWGLAEFYHPGME 1041
Query: 189 WTLCGTPEYL-APEIILS-KGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQI 239
+ + Y PE++L + Y+ ++D W+LG + M P +P Q+
Sbjct: 1042YNVRVASRYFKGPELLLDYQMYDYSLDMWSLGCMFASMIFRKEPLLP-RPRQL 1197
>20152
Length = 445
Score = 50.8 bits (120), Expect = 8e-07, Method: Compositional matrix adjust.
Identities = 29/96 (30%), Positives = 44/96 (45%), Gaps = 1/96 (1%)
Frame = +1
Query: 200 PEIILSKGYN-KAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDL 258
PEI+L Y+ AVD W+LGV++Y + G PF + I+ + + P H S
Sbjct: 1 PEILLGDSYDAPAVDVWSLGVILYMLVVGEAPFQEANDSETLTMIMDCRYQIPPHISHKC 180
Query: 259 KDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTD 294
+DL+ +LQ + R + I H W D
Sbjct: 181 QDLIEKMLQREPVDR-----ASLPHILAHPWLNDGD 273
>37602
Length = 804
Score = 50.4 bits (119), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 26/90 (28%), Positives = 43/90 (47%)
Frame = -1
Query: 89 QAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFE 148
+ VN V S+ L++ MEY GG M G +EP F + +
Sbjct: 354 RIVNIQTFVGYFDSYLRREKLWIAMEYCGGGSMQDIYHVTGPLTEPQIAFVCRETLKGLH 175
Query: 149 YLHSLDLIYRDLKPENLLIDQQGYIQVTDF 178
YLH ++RD+K N+L+ ++G +++ DF
Sbjct: 174 YLHRRGKMHRDIKGANILLTEEGDVKLADF 85
>00715
Length = 1788
Score = 50.1 bits (118), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 55/232 (23%), Positives = 100/232 (43%), Gaps = 31/232 (13%)
Frame = +1
Query: 49 RVMLVK--HKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDN 106
R + VK HK + N A++ +++ + +N IL A + F+D
Sbjct: 1 RTVAVKIYHKRSSNPRALRQSYSNELLAFRCGLRHVNVVSILGATSL-------HRFEDG 159
Query: 107 SNLYMVMEYVPGGEMFSHLRRIGRFSEPHARF-YAAQIVLTFEYLHSLDLIYRDLKPENL 165
+ ++ MEYV + + L + + R A Q+ YLHS+++++ DLKP N
Sbjct: 160 A--WLAMEYVGPLNLQTILNDHQQDIDSSMRLSLALQMARGLHYLHSINIVHLDLKPANC 333
Query: 166 LIDQQGYIQVTDFGFAKR------------------------VKGRTWT--LCGTPEYLA 199
L+ + +++ DFG + V+G W L GT Y A
Sbjct: 334 LLTRDLKLRIADFGCCHQLTPTGLDMGEREGGMAGNELELTPVQG-AWKNELAGTLAYRA 510
Query: 200 PEIILSKGYNKAV--DWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVR 249
PE++ KG +V D ++LG+ +++M P+ + ++VS +R
Sbjct: 511 PELL--KGLQPSVRSDVYSLGITLWQMCTRQGPYEGVPAHAVVYQVVSKDLR 660
>14116
Length = 1017
Score = 47.4 bits (111), Expect = 8e-06, Method: Compositional matrix adjust.
Identities = 27/123 (21%), Positives = 61/123 (49%), Gaps = 9/123 (7%)
Frame = -1
Query: 111 MVMEYVPGGEMFSHLRRIGRFSEPHAR---FYAAQIVLTFEYLHSLDLIYRDLKPENLLI 167
+V+ ++ G++ +++R +P + Y I +YL L ++RDL N ++
Sbjct: 393 VVLPFMKHGDLLTYIR--DDQHQPTIKDLIMYGVDIARGMDYLAGLKFVHRDLAARNCML 220
Query: 168 DQQGYIQVTDFGFAKRVKGRTWTLCGTP------EYLAPEIILSKGYNKAVDWWALGVLI 221
D+ +++V DFG A+ + + + +++A E + Y+ D W+ GV++
Sbjct: 219 DEDFHVKVADFGLARDIYEKEYYSSENKKAKLPVKWMALESLEKGNYDSKTDVWSYGVVL 40
Query: 222 YEM 224
+E+
Sbjct: 39 WEL 31
>27274
Length = 396
Score = 46.6 bits (109), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 28/102 (27%), Positives = 49/102 (48%), Gaps = 11/102 (10%)
Frame = -1
Query: 201 EIILSKGYNKAVDWWALGVLIYEMAAGYPPF--------FADQPIQIYEKIVSGKVRFPS 252
E++ + + VD W+LG+L++E+ +G+ PF A + +Y +I+ G R
Sbjct: 375 ELLRGQQHGPTVDMWSLGILLHELLSGHVPFEPERGSRQMARNMMAVYAQIIRGSSRDVC 196
Query: 253 H---FSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFA 291
S+ D LR L+Q++ TKR + +H W A
Sbjct: 195 DGLALSTHGADFLRRLVQLEDTKRLTS-----QQAFSHPWIA 85
>17300
Length = 480
Score = 46.2 bits (108), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 41/152 (26%), Positives = 71/152 (46%), Gaps = 14/152 (9%)
Frame = +1
Query: 150 LHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRT----WTLCGTP---EYLAPEI 202
L + ++RDL N+L+++ +V DFG ++ ++ T +T G + APE
Sbjct: 22 LADMGYVHRDLAARNILVNEILVCKVADFGLSREIESDTTEGAYTTKGGKIPVRWTAPEA 201
Query: 203 ILSKGYNKAVDWWALGVLIYE-MAAGYPPFFADQPIQIYEKIVSGKVRFPSH------FS 255
I + + A D W+ GV+++E M+ G P++ + Q K V R P H S
Sbjct: 202 IAYRKFTSASDVWSFGVVMWEVMSYGERPYW-NWSNQDVIKAVEKGYRLPLHGLSGSPSS 378
Query: 256 SDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNH 287
+D + L ++ TK N+ G N + H
Sbjct: 379 TDARRLAEG--EISQTK---NVHGG*NTRQTH 459
>07291
Length = 833
Score = 45.8 bits (107), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 25/100 (25%), Positives = 54/100 (54%), Gaps = 7/100 (7%)
Frame = +1
Query: 139 YAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTW-TLCGTP-- 195
+ QI YL + +++R+L N ++ + G +Q++D+G + +++ T +P
Sbjct: 64 FGRQIADGMAYLQEVKVVHRNLAARNCIVTEDGRLQLSDYGVTGSLFPQSYYTADDSPAR 243
Query: 196 ---EYLAPEIILSKGYNKAVDWWALGVLIYE-MAAGYPPF 231
+++APE I + ++ D WA GV+++E + G P+
Sbjct: 244 DLVKWMAPETIDNFHFSSKSDVWAFGVVLWELLTRGITPY 363
>02638
Length = 1490
Score = 44.7 bits (104), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 27/105 (25%), Positives = 49/105 (46%), Gaps = 5/105 (4%)
Frame = +1
Query: 191 LCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFA---DQPIQIYEKIVSG- 246
L GT ++APE++ + Y +A D W++G ++ EM PP+ + + + KI S
Sbjct: 16 LLGTIAFMAPEVLRGESYGRACDVWSVGCVMIEMCTCRPPWNSHDISNHLALIFKIASSV 195
Query: 247 -KVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWF 290
P + S ++DL+ L+ D + + D+ H F
Sbjct: 196 DPPPIPENMSPPVRDLMLRCLEQD-----SDFRPSAKDLLMHPLF 315
>17932
Length = 597
Score = 44.3 bits (103), Expect = 8e-05, Method: Compositional matrix adjust.
Identities = 30/100 (30%), Positives = 46/100 (46%)
Frame = -3
Query: 235 QPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTD 294
QPI I I +V S S + +DL+ LL G + G +++ H +F T D
Sbjct: 517 QPITIS*TIRQTQVPPHSSVSKEARDLISQLLSD------GKSRLGWPELQQHPFFKTVD 356
Query: 295 WIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINE 334
W I R P++P DTS+FD+ E+ +I+
Sbjct: 355 WANI--RNAMPPYVPSISSLDDTSHFDEVEKARPAPNIDS 242
Score = 32.3 bits (72), Expect = 0.28, Method: Compositional matrix adjust.
Identities = 16/41 (39%), Positives = 20/41 (48%), Gaps = 2/41 (4%)
Frame = -2
Query: 214 WWALGVLIYEMAAGYPPFFADQP--IQIYEKIVSGKVRFPS 252
WW+LGV YEM G PF D + Y I++ K S
Sbjct: 596 WWSLGVCAYEMLFGCTPFTDDDGSMVATYNNIMNYKTNSSS 474
>33586
Length = 551
Score = 43.1 bits (100), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 16/49 (32%), Positives = 33/49 (67%)
Frame = +2
Query: 95 FLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQI 143
F+V L ++F+ LY+++E++ GG++F+ L + F+E +FY A++
Sbjct: 404 FIVHLHYAFQTEGKLYLILEFLRGGDLFTRLSKEVMFTEEDVKFYLAEL 550
Score = 29.3 bits (64), Expect = 2.3, Method: Compositional matrix adjust.
Identities = 13/20 (65%), Positives = 14/20 (70%)
Frame = +1
Query: 31 AHLDQFERIKTLGTGSFGRV 50
A QFE +K LG GSFGRV
Sbjct: 205 ADPSQFELLKVLGQGSFGRV 264
>18401
Length = 463
Score = 42.4 bits (98), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 16/42 (38%), Positives = 26/42 (61%)
Frame = -3
Query: 190 TLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPF 231
T+ T Y APE+IL G++ D W++G +++E+ GY F
Sbjct: 455 TIVSTRHYRAPEVILELGWSHPCDVWSVGCIMFELYTGYTLF 330
>12672
Length = 773
Score = 41.2 bits (95), Expect = 6e-04, Method: Compositional matrix adjust.
Identities = 28/88 (31%), Positives = 46/88 (52%), Gaps = 7/88 (7%)
Frame = +3
Query: 147 FEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGF---AKRVKGRTW----TLCGTPEYLA 199
+YL+ ++RD+K N+L+D + +V DF A +G+T + GT YLA
Sbjct: 30 IQYLNDNGHVHRDIKTANILLDSEYTAKVGDFATVVSAPSGEGKTVQNASVVIGTAAYLA 209
Query: 200 PEIILSKGYNKAVDWWALGVLIYEMAAG 227
PE I K +D ++ GV++ E+ G
Sbjct: 210 PEAIHFDVSTK-LDSYSFGVVLLEVITG 290
>31489
Length = 329
Score = 40.8 bits (94), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 24/69 (34%), Positives = 40/69 (57%), Gaps = 4/69 (5%)
Frame = +3
Query: 102 SFKDNSNLYMVMEYVPGGEMFSHLRRI----GRFSEPHARFYAAQIVLTFEYLHSLDLIY 157
S+ D ++++V + M S L RI +E H R++ QI+ +Y+HS ++++
Sbjct: 72 SYHDFKDIHVVFDL-----MESDLHRIIYSDQPLTEEHIRYFLYQILRGLKYIHSANVVH 236
Query: 158 RDLKPENLL 166
RDLKP NLL
Sbjct: 237 RDLKPSNLL 263
>29590
Length = 320
Score = 40.4 bits (93), Expect = 0.001, Method: Composition-based stats.
Identities = 17/41 (41%), Positives = 25/41 (60%)
Frame = +3
Query: 191 LCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPF 231
+ GTP+Y+APE++ + + D W+LGVL Y M PF
Sbjct: 54 IIGTPDYVAPEVLDYEPLSIQTDMWSLGVLSYVMLTACSPF 176
>26009
Length = 886
Score = 40.0 bits (92), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 23/72 (31%), Positives = 35/72 (48%), Gaps = 3/72 (4%)
Frame = +3
Query: 119 GEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQV--- 175
G + RR A+ Q+V +++HS L++RD+KPEN+LI + +V
Sbjct: 666 GTCLTPSRRNKACGSREAKSVMKQLVSALDFMHSKQLVHRDIKPENVLILTPDFSRVS*W 845
Query: 176 TDFGFAKRVKGR 187
T A RV R
Sbjct: 846 TSA*LANRVHRR 881
>14477
Length = 493
Score = 40.0 bits (92), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 34/152 (22%), Positives = 71/152 (46%), Gaps = 2/152 (1%)
Frame = -1
Query: 35 QFERIKTLGTGSFGRVM--LVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVN 92
Q + +K LG G+FG VM + + + A+K+L + Q E + E +++ ++
Sbjct: 484 QMDELK-LGAGNFGSVMKGVCRLDDREIPVAIKVLKNADLDPSVQSE-LIKEAEVMKKMD 311
Query: 93 FPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHS 152
+V+L + + +V+E G + L + + Q+ EYL +
Sbjct: 310 HMHIVRL-IGLCEGETMMLVLELAKLGPLNKFLPKNKHLPLWNILELMWQVSQGMEYLEA 134
Query: 153 LDLIYRDLKPENLLIDQQGYIQVTDFGFAKRV 184
++RDL N+L+ + + +++DFG +K +
Sbjct: 133 NKFVHRDLAARNILLCDEHFAKISDFGMSKTL 38
>11404
Length = 563
Score = 39.7 bits (91), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 43/149 (28%), Positives = 72/149 (48%), Gaps = 6/149 (4%)
Frame = +1
Query: 25 SPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKIL-DKQKVVKLKQIEHTLN 83
SP + A D++E +G GSFG+V+ A+KI+ +K+ + QIE L
Sbjct: 118 SPGEKWA--DRYEIDSLIGKGSFGQVVKAYDHTDNEQVAIKIIKNKKPFLNQAQIEVKLL 291
Query: 84 EKRILQAV-NFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIG--RFSEPHARFYA 140
E N ++V+L+ F S+L +V E + ++ LR S R +A
Sbjct: 292 EMMNRHDTDNKYYIVRLKRHFMFRSHLCLVFELLSYN-LYDLLRNTNFRGVSLNLTRKFA 468
Query: 141 AQIVLTFEYLHS--LDLIYRDLKPENLLI 167
Q+ +L + + +I+ DLKPEN+L+
Sbjct: 469 QQLCTALLFLATPEMSIIHCDLKPENILL 555
>37063
Length = 455
Score = 38.1 bits (87), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 24/78 (30%), Positives = 40/78 (51%), Gaps = 16/78 (20%)
Frame = -2
Query: 160 LKPENLL---IDQQGYIQVTDFGFAKRVKG--------RTWTLCGTPEYLAPEII----- 203
LKPEN+L +D+ +++ DF A + T G+ EY+APE++
Sbjct: 454 LKPENILCEHLDEVVPLKICDFDLASGINCDGDGTKTPELLTPVGSAEYMAPEVVDAWVG 275
Query: 204 LSKGYNKAVDWWALGVLI 221
S Y+K D W+LG+++
Sbjct: 274 ESFSYDKRCDMWSLGIIL 221
>17516
Length = 453
Score = 38.1 bits (87), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 17/39 (43%), Positives = 28/39 (71%), Gaps = 1/39 (2%)
Frame = -3
Query: 190 TLCGTPEYLAPEIILSKG-YNKAVDWWALGVLIYEMAAG 227
TL GTP Y+APE++L KG Y+ D ++L ++++E+ G
Sbjct: 442 TLAGTPVYMAPEVLLQKGQYDMKADVYSLAIILWELWYG 326
>20640
Length = 1492
Score = 38.1 bits (87), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 25/99 (25%), Positives = 47/99 (47%), Gaps = 6/99 (6%)
Frame = +1
Query: 156 IYRDLKPENLLIDQQGYIQVTDFGFAKRVKG----RTWTLCGTP-EYLAPEIILSKGYNK 210
++RDL N L+ ++++DFG A+ V R P ++ E IL ++
Sbjct: 10 VHRDLATRNCLVGHDLVVKISDFGLARSVHSVDYYRGSEHDAIPIRWMPLEAILYNKFST 189
Query: 211 AVDWWALGVLIYEM-AAGYPPFFADQPIQIYEKIVSGKV 248
D W+ GV+++E+ A P++ ++ + GKV
Sbjct: 190 QSDVWSFGVVLWEIFAFALQPYYGLTHEEVVRFVKEGKV 306
>18481
Length = 437
Score = 37.4 bits (85), Expect = 0.008, Method: Compositional matrix adjust.
Identities = 23/75 (30%), Positives = 38/75 (50%), Gaps = 3/75 (4%)
Frame = -1
Query: 120 EMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQ---VT 176
E+F +R RF+ + Q++ E++H I+RDLKP+N L+ + +
Sbjct: 233 ELFVICKR--RFTLKTILMVSDQLLSRLEFIHQKCFIHRDLKPDNFLMGLGRHCHRLYII 60
Query: 177 DFGFAKRVKGRTWTL 191
DFG +KR K T+
Sbjct: 59 DFGLSKRYKDTQGTM 15
>17637
Length = 447
Score = 37.4 bits (85), Expect = 0.010, Method: Compositional matrix adjust.
Identities = 24/89 (26%), Positives = 42/89 (47%), Gaps = 6/89 (6%)
Frame = +1
Query: 164 NLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEY-----LAPEIILSKGYNKAVDWWALG 218
N +ID Q +++TD ++ + + G EY L+ E + YN+ D W+ G
Sbjct: 1 NCVIDDQLRVKLTDSALSRDLFSGDYNCLGDGEYRPIKWLSLEALQKSHYNEGSDVWSFG 180
Query: 219 VLIYEMAA-GYPPFFADQPIQIYEKIVSG 246
VL++EM G P+ P ++ + G
Sbjct: 181 VLMWEMCTLGKLPYAEIDPYEMEHYLKDG 267
>18996
Length = 491
Score = 37.0 bits (84), Expect = 0.010, Method: Compositional matrix adjust.
Identities = 21/74 (28%), Positives = 41/74 (55%), Gaps = 5/74 (6%)
Frame = +2
Query: 156 IYRDLKPENLLIDQQGYIQVTDFGFAK--RVKGRTWTLCGTP---EYLAPEIILSKGYNK 210
I+RDL N+L+D+ ++++DFG A+ G + + ++ +PE I + ++
Sbjct: 2 IHRDLAARNILVDR-SCVKISDFGLAQFANADGYYYGISQRDIPIKWYSPEAIETCKFSS 178
Query: 211 AVDWWALGVLIYEM 224
D W+ GV ++EM
Sbjct: 179 YSDVWSYGVTLFEM 220
>17253
Length = 483
Score = 37.0 bits (84), Expect = 0.011, Method: Compositional matrix adjust.
Identities = 20/86 (23%), Positives = 44/86 (51%), Gaps = 12/86 (13%)
Frame = -1
Query: 111 MVMEYVPGGEMFSHLRR---------IGRFSEPHAR---FYAAQIVLTFEYLHSLDLIYR 158
++ME+ G++ S LR+ ++ AR +A + ++ + +++R
Sbjct: 315 ILMEFCCHGDLLSFLRKRRPDRTVFLTSTANDLTARDFFSFALHVARGMAHVANNKIVHR 136
Query: 159 DLKPENLLIDQQGYIQVTDFGFAKRV 184
D+ N+LI ++ +V+DFG ++RV
Sbjct: 135 DVAARNVLISERNVCKVSDFGLSRRV 58
>21800
Length = 855
Score = 36.6 bits (83), Expect = 0.014, Method: Compositional matrix adjust.
Identities = 35/148 (23%), Positives = 61/148 (41%), Gaps = 3/148 (2%)
Frame = +2
Query: 23 WESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTL 82
W P + A L L V + E+ HY LD+ K++K +
Sbjct: 305 WTVPCRQKAGLGSLLHCLALLGSQL*AVCRFEGCESAQHYTETALDEIKLLKCVRNSDET 484
Query: 83 NEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEP--HARFYA 140
+ R + L + S + +++ MV E V G + + R P + +
Sbjct: 485 DPAR---EKSVQLLDDFKISGVNGTHVCMVFE-VLGYNLLKLIIRSNYQGIPVHNVKLII 652
Query: 141 AQIVLTFEYLHS-LDLIYRDLKPENLLI 167
Q++ YLH+ ++I+ D+KPEN+LI
Sbjct: 653 RQVLEGLNYLHAKCNIIHTDIKPENILI 736
>06358
Length = 1517
Score = 36.6 bits (83), Expect = 0.015, Method: Compositional matrix adjust.
Identities = 32/154 (20%), Positives = 68/154 (44%), Gaps = 22/154 (14%)
Frame = +3
Query: 142 QIVLTFEYLHS-LDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTP----- 195
Q+ +LH+ +++R++ PE +++ + G ++ + F R T P
Sbjct: 384 QVTEALGFLHNDAKMMHRNVCPEAIMLTKLGSWKLAGYEFCVRSSDPQSTDPSYPFYEWR 563
Query: 196 -----------EYLAPEIILSKGYNKAVDWWALGVLIYEM-AAGYPPFFADQPIQIY--- 240
+++APE +L+ D ++LG+L+Y + A G P F + + +
Sbjct: 564 SDIAPVTQPHLDFMAPEYVLTMQCGTGSDMFSLGLLVYSVFAKGKPLFECNGELSAFKSN 743
Query: 241 -EKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKR 273
E++ +V DL+D ++ LL ++ R
Sbjct: 744 AEELRHMRVSLLGVVPEDLRDHVKLLLNIEPAVR 845
>01106
Length = 878
Score = 36.2 bits (82), Expect = 0.019, Method: Compositional matrix adjust.
Identities = 40/166 (24%), Positives = 71/166 (42%), Gaps = 15/166 (9%)
Frame = +3
Query: 17 EDFLKKWESPAQNTAHLD-QFERIKTLGTGSFGRVML-----------VKHKETGNHYAM 64
D+ K P +N + ++ I+ LG G F V L +K ++ HY
Sbjct: 264 RDYCKGGYHPVKNGDLFNGRYHVIRKLGWGHFSTVWLCWDLTCKRFVALKVVKSAQHYTE 443
Query: 65 KILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSH 124
LD+ K++K + + R A L + S + +++ MV E V G +
Sbjct: 444 TALDEVKLLKCVRESDVADPAR---AKCVQLLDDFKISGVNGTHVAMVFE-VLGYNLLKL 611
Query: 125 LRRIGRFSEP--HARFYAAQIVLTFEYLHS-LDLIYRDLKPENLLI 167
+ R P + + Q++ Y+H+ +I+ D+KPEN+LI
Sbjct: 612 IIRSNYQGIPIHNVKLIIRQVLEGLSYMHAKCRIIHTDIKPENILI 749
>36481
Length = 806
Score = 35.8 bits (81), Expect = 0.024, Method: Compositional matrix adjust.
Identities = 33/132 (25%), Positives = 60/132 (45%), Gaps = 4/132 (3%)
Frame = +2
Query: 43 GTGSFGRVMLVKHKETGNHYAMKIL-DKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEF 101
G G+FG+V+ K G+ A+KI+ + K + ++E + EK + + +
Sbjct: 389 GEGTFGKVVQCKDLLKGDDIALKIIKNVDKYREAAKLEINVLEKLREKDPHAKHMCVQML 568
Query: 102 SFKDNSNLYMVMEYVPGGEMFSHLR--RIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRD 159
+ D + ++ G +F L+ G + R + Q+ +LH L + D
Sbjct: 569 DWFDYHGHVCISFHMLGLSVFDFLKDNSYGAYPIEQVRHISYQLCYAVNFLHENQLTHTD 748
Query: 160 LKPENLL-IDQQ 170
LKPEN+L +D Q
Sbjct: 749 LKPENILFVDSQ 784
>26052
Length = 562
Score = 35.8 bits (81), Expect = 0.024, Method: Compositional matrix adjust.
Identities = 16/31 (51%), Positives = 22/31 (70%)
Frame = -1
Query: 35 QFERIKTLGTGSFGRVMLVKHKETGNHYAMK 65
Q+ K LG GSFG+VM ++HK+TG A+K
Sbjct: 388 QYLFXKLLGVGSFGKVMALQHKDTGETLAVK 296
>25360
Length = 751
Score = 35.4 bits (80), Expect = 0.038, Method: Compositional matrix adjust.
Identities = 21/54 (38%), Positives = 28/54 (51%), Gaps = 5/54 (9%)
Frame = -3
Query: 158 RDLKPENLLIDQQGYI-QVTDFGFAKRVKGRTWT--LCGTPEYL--APEIILSK 206
R L P L QG +V D G+A V G+TWT +CGTP + P + S+
Sbjct: 422 RSLTPGGLEALFQGQCPRVQDLGWASHVNGKTWTHYVCGTPHWQHDCPRRVRSR 261
>11089
Length = 1213
Score = 34.7 bits (78), Expect = 0.050, Method: Compositional matrix adjust.
Identities = 21/54 (38%), Positives = 28/54 (51%), Gaps = 5/54 (9%)
Frame = +2
Query: 158 RDLKPENLLIDQQGYI-QVTDFGFAKRVKGRTWT--LCGTPEYL--APEIILSK 206
R L P L QG +V D G+A V G+TWT +CGTP + P + S+
Sbjct: 974 RSLTPGGLEALFQGQCPRVQDLGWASHVNGKTWTHYVCGTPHWQHDCPRRVRSR 1135
>21210
Length = 518
Score = 34.7 bits (78), Expect = 0.065, Method: Compositional matrix adjust.
Identities = 27/91 (29%), Positives = 43/91 (47%), Gaps = 10/91 (10%)
Frame = +3
Query: 193 GTPEYLAPEII----LSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIY---EKIVS 245
G Y+APE I S GY+ D W+LG+ + E+A G P+ + + I+ +++V
Sbjct: 6 GCRPYMAPERIDPRASSHGYDVRSDVWSLGITLMELATGRFPY--RKWVSIFDQLQQVVR 179
Query: 246 GKVRFPSH---FSSDLKDLLRNLLQVDLTKR 273
G H FS D + + L D +R
Sbjct: 180 GVAPCLPHDGAFSHDFVNFVNKCLTKDEKQR 272
>28865
Length = 342
Score = 33.5 bits (75), Expect = 0.13, Method: Compositional matrix adjust.
Identities = 19/60 (31%), Positives = 29/60 (48%), Gaps = 3/60 (5%)
Frame = -3
Query: 13 AKAKEDFLKKWESPAQNTAHLDQFERI---KTLGTGSFGRVMLVKHKETGNHYAMKILDK 69
AK E+ ++PA + Q +I LG+G FG V H+ T A+K++DK
Sbjct: 274 AKDNENVTANEDTPADKQVDISQLYQIFPEDVLGSGQFGIVYGGCHRRTNREVAIKVIDK 95
>17591
Length = 474
Score = 32.7 bits (73), Expect = 0.20, Method: Compositional matrix adjust.
Identities = 14/46 (30%), Positives = 28/46 (60%)
Frame = +2
Query: 222 YEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQ 267
+EM G PPF++ ++YE I+ +R ++ S+ +++L LL+
Sbjct: 2 FEMLYGLPPFYSRDTSEMYENILYKPLRLRTNVSAAGRNILEELLK 139
>30339
Length = 384
Score = 32.0 bits (71), Expect = 0.33, Method: Compositional matrix adjust.
Identities = 15/25 (60%), Positives = 17/25 (68%)
Frame = -2
Query: 32 HLDQFERIKTLGTGSFGRVMLVKHK 56
HL F IK LG GSFG+VML + K
Sbjct: 80 HLHDFNFIKVLGKGSFGKVMLAERK 6
>31120
Length = 439
Score = 31.6 bits (70), Expect = 0.47, Method: Compositional matrix adjust.
Identities = 24/95 (25%), Positives = 43/95 (45%), Gaps = 1/95 (1%)
Frame = +1
Query: 201 EIILSKGYN-KAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLK 259
E++ Y+ K D W+LGV+++ M G PF ++ E S K F +
Sbjct: 1 EVVCGVPYDPKMADAWSLGVILFIMLNGKMPFDDSNLNKLLEDQRSKKYSFRRKLQDLVS 180
Query: 260 DLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTD 294
R+ + V L + ++ +N++ N +W T D
Sbjct: 181 PNARSTVSV-LLEPNSAMRWDLNEVLNCQWLQTID 282
>00638
Length = 1595
Score = 30.8 bits (68), Expect = 0.91, Method: Compositional matrix adjust.
Identities = 11/38 (28%), Positives = 25/38 (65%)
Frame = +2
Query: 131 FSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLID 168
F++ RFY +++ ++ HS+ +++RD+KP L++
Sbjct: 407 FTDYDIRFYLYELMKALDFCHSMGIMHRDVKPSPPLVN 520
>16350
Length = 1108
Score = 30.0 bits (66), Expect = 1.2, Method: Compositional matrix adjust.
Identities = 10/34 (29%), Positives = 18/34 (52%)
Frame = +2
Query: 194 TPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAG 227
T +Y E+++ GY D W+ + +E+A G
Sbjct: 419 TRQYRCLEVLIGAGYGTPADIWSTACMAFELATG 520
>32357
Length = 625
Score = 30.0 bits (66), Expect = 1.3, Method: Compositional matrix adjust.
Identities = 19/63 (30%), Positives = 33/63 (52%), Gaps = 1/63 (1%)
Frame = -2
Query: 34 DQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQ-AVN 92
++ +K +G+GSFG + L H +G A+K+ + K K Q+ + R+LQ V
Sbjct: 438 GKYRLMKKIGSGSFGEIYLGVHNTSGEEVAVKL--ELKNAKHPQLYYESKLYRVLQGGVG 265
Query: 93 FPF 95
P+
Sbjct: 264 IPY 256
>06167
Length = 1470
Score = 28.9 bits (63), Expect = 3.2, Method: Compositional matrix adjust.
Identities = 12/43 (27%), Positives = 22/43 (51%)
Frame = -2
Query: 174 QVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWA 216
+ D FA R +CG+ + P ++L+ NK+V +W+
Sbjct: 131 AIIDESFACRFCM*YCVVCGSKYLILPSVLLNLNINKSVSFWS 3
>36002
Length = 253
Score = 28.9 bits (63), Expect = 3.4, Method: Composition-based stats.
Identities = 18/55 (32%), Positives = 26/55 (47%), Gaps = 4/55 (7%)
Frame = +1
Query: 239 IYEKIVSGKVRFPSH----FSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKW 289
++ +I G FPS SS KDL+R+LL + KR+ D+ H W
Sbjct: 58 LFNRIQDGNYFFPSMEWSAISSSAKDLIRHLLVREPRKRY-----SAADVLKHPW 207
>23319
Length = 2235
Score = 28.5 bits (62), Expect = 4.0, Method: Compositional matrix adjust.
Identities = 10/33 (30%), Positives = 19/33 (57%)
Frame = +3
Query: 200 PEIILSKGYNKAVDWWALGVLIYEMAAGYPPFF 232
P++ +K Y+ ++D W+ G + E+A P F
Sbjct: 3 PDVYXAKMYSTSIDMWSAGCIFAELANAGRPLF 101
>29360
Length = 363
Score = 27.7 bits (60), Expect = 7.7, Method: Compositional matrix adjust.
Identities = 12/33 (36%), Positives = 19/33 (57%)
Frame = +3
Query: 135 HARFYAAQIVLTFEYLHSLDLIYRDLKPENLLI 167
+ R Q++ L L LI+ DLKPEN+++
Sbjct: 261 YIRPITQQVLTALRKLKQLGLIHADLKPENIML 359
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000263125 | hsapiens_gene_ensembl | Protein kinase
C theta type (EC 2.7.11.13) (nPKC-theta).
[Source:Uniprot/SWISSPROT;Acc:Q04759]
(706 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
18484 192 4e-57
30755 193 2e-49
18663 145 7e-35
03240 138 6e-33
00486 128 7e-30
27405 102 5e-22
17722 101 1e-21
26156 80 6e-21
12721 96 4e-20
15910 96 4e-20
26560 95 1e-19
31885 91 2e-18
14420 86 6e-17
18921 84 1e-16
25445 83 3e-16
06405 82 5e-16
00300 82 5e-16
09606 79 8e-15
01060 77 2e-14
21433 62 6e-14
01707 74 2e-13
01392 74 3e-13
13212 72 9e-13
14126 70 2e-12
25019 70 2e-12
11353 67 2e-11
21079 65 7e-11
38560 64 3e-10
13592 63 3e-10
22804 63 4e-10
21808 62 6e-10
13066 62 1e-09
19361 60 2e-09
01756 59 6e-09
17591 52 6e-09
17932 43 9e-09
32957 58 1e-08
04852 58 2e-08
07940 58 2e-08
19094 57 3e-08
01718 57 3e-08
20152 56 6e-08
35187 55 7e-08
29581 55 9e-08
04591 55 1e-07
00392 52 8e-07
02638 51 1e-06
12786 50 2e-06
01966 50 2e-06
11185 50 4e-06
29590 49 8e-06
14116 49 8e-06
27546 48 1e-05
09007 48 1e-05
08294 42 4e-05
26711 46 6e-05
28638 44 2e-04
04138 44 3e-04
19761 44 3e-04
37602 43 4e-04
12672 42 8e-04
27274 41 0.001
18401 41 0.002
17300 40 0.003
17516 40 0.005
07291 39 0.006
33586 39 0.006
17637 39 0.010
13305 38 0.012
30743 38 0.017
20640 37 0.019
36002 37 0.026
30339 35 0.13
17975 34 0.17
18996 32 0.60
23319 32 1.1
26009 32 1.1
26052 31 1.5
03294 30 3.8
13477 29 6.1
12041 29 7.0
>18484
Length = 635
Score = 192 bits (488), Expect(2) = 4e-57, Method: Compositional matrix adjust.
Identities = 94/159 (59%), Positives = 109/159 (68%)
Frame = +1
Query: 465 DLMYHIQSCHKFDLSRATFYAAEIILGLQFLHSKGIVYRXXXXXXXXXXXXGHIKIADFG 524
DLMY IQ KF A FYAAEI +GL FLH +GI+YR GHIKIADFG
Sbjct: 1 DLMYRIQQEGKFKEPVAAFYAAEIAVGLFFLHDQGIIYRDLKLDNVMLDSEGHIKIADFG 180
Query: 525 MCKENMLGDAKTNTFCGTPDYIAPEILLGQKYNHSVDWWSFGVLLYEMLIGQSPFHGQDE 584
MCKE M GDA T TFCGTPDYIAPEI+L Q Y+ SVDWW++GVLL+EML GQ PF G+DE
Sbjct: 181 MCKEGMTGDATTRTFCGTPDYIAPEIVLYQPYSKSVDWWAYGVLLFEMLAGQPPFDGEDE 360
Query: 585 EELFHSIRMDNPFYPRWLEKEAKDLLVKLFVREPEKRLG 623
+ELF SI N YP+ + +EA L L ++ P KRLG
Sbjct: 361 DELFSSITDHNVSYPKAMSREAVSLCKGLLMKNPTKRLG 477
Score = 48.1 bits (113), Expect(2) = 4e-57, Method: Composition-based stats.
Identities = 18/42 (42%), Positives = 26/42 (61%)
Frame = +2
Query: 627 DIRQHPLFREINWEELERKEIDPPFRPKVKSPFDCSNFDKEF 668
DIR H FR I W++++ E+ PP++PK+ NFDK F
Sbjct: 500 DIRDHAFFRRIVWDKIKSMEVQPPYKPKITDRRKAENFDKSF 625
>30755
Length = 1137
Score = 193 bits (490), Expect = 2e-49, Method: Compositional matrix adjust.
Identities = 98/234 (41%), Positives = 137/234 (58%), Gaps = 6/234 (2%)
Frame = +2
Query: 469 HIQSCHKFDLSRATFYAAEIILGLQFLHSKGIVYRXXXXXXXXXXXXGHIKIADFGMCKE 528
H+ F R FY AEII L +LHS+GI+YR GHIK+ADFG+CKE
Sbjct: 2 HLSHERIFTEERTRFYGAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCKE 181
Query: 529 NMLGDAKTNTFCGTPDYIAPEILLGQKYNHSVDWWSFGVLLYEMLIGQSPFHGQDEEELF 588
++ T TFCGTP+Y+APE+L Y +VDWW GV++YEM+ G+ PF+ +D + LF
Sbjct: 182 DITYGRTTKTFCGTPEYLAPEVLDDNDYGRAVDWWGTGVVMYEMICGRLPFYNRDHDVLF 361
Query: 589 HSIRMDNPFYPRWLEKEAKDLLVKLFVREPEKRLGVRGD----IRQHPLFREINWEELER 644
I +++ +PR + EAK LL L ++P RLG D I+ HP F INW +L +
Sbjct: 362 TLILVEDVKFPRNITDEAKSLLSGLLAKDPRNRLGGGQDDVKEIQAHPFFASINWTDLVQ 541
Query: 645 KEIDPPFRPKVKSPFDCSNFDKEFLNEKPRLSFADRA--LINSMDQNMFRNFSF 696
K+I PPF+P+V S D FD+EF E L+ D L + ++ +F FS+
Sbjct: 542 KKITPPFKPQVTSDTDTRYFDEEFTGESVELTPPDPTGPLXSIAEEPLFPQFSY 703
>18663
Length = 600
Score = 145 bits (365), Expect = 7e-35, Method: Compositional matrix adjust.
Identities = 79/182 (43%), Positives = 105/182 (57%), Gaps = 14/182 (7%)
Frame = +2
Query: 537 NTFCGTPDYIAPEILLGQKYNHSVDWWSFGVLLYEMLIGQSPF---------HGQDEEEL 587
+TFCGTP+YIAPEIL G+ Y SVDWW+ GVLLYEML G+SPF E+ L
Sbjct: 2 STFCGTPNYIAPEILRGEDYGFSVDWWALGVLLYEMLAGRSPFDIAGASENPDQNTEDYL 181
Query: 588 FHSIRMDNPFYPRWLEKEAKDLLVKLFVREPEKRLGVRG-----DIRQHPLFREINWEEL 642
F I PR L +A +L + P RLG DI HP F+ I+WE L
Sbjct: 182 FQVILEKTIRIPRSLSVKAASVLKGFLNKNPADRLGCHRESAFMDIVNHPFFKVIDWEML 361
Query: 643 ERKEIDPPFRPKVKSPFDCSNFDKEFLNEKPRLSFADRALINSMDQNMFRNFSFMNPGME 702
ERK++ PPF+P++ S D +NF EF E +L+ D +I+S+DQ+ F F ++NP +
Sbjct: 362 ERKQVSPPFKPRLDSDRDLANFPIEFTGEPVQLTPDDDHVIDSIDQSEFEGFEYVNPLLM 541
Query: 703 RL 704
L
Sbjct: 542 SL 547
>03240
Length = 1683
Score = 138 bits (348), Expect = 6e-33, Method: Compositional matrix adjust.
Identities = 98/334 (29%), Positives = 154/334 (46%), Gaps = 52/334 (15%)
Frame = -3
Query: 384 KMLGKGSFGKVFLAEFKKTNQFFAIKAXXXXXXXXXXXXECTMVEKRVLSLAWEHPFLTH 443
K LG G+FG+V L T +A+K E+ +L+ A ++ ++
Sbjct: 1273 KTLGVGAFGEVSLCRKNDTGMLYAMKTLRKSDVLKRNQVAHVKAERDILAEA-DNEWVVK 1097
Query: 444 MFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEIILGLQFLHSKGIVYR 503
++ +FQ L+FVM+Y+ GGDLM + D A FY AE++ ++ +H G ++R
Sbjct: 1096 LYYSFQDHNYLYFVMDYVPGGDLMGLLIRMEILDEPLARFYVAELVQAIESVHRMGFIHR 917
Query: 504 XXXXXXXXXXXXGHIKIADFGMC--------------------KENMLGDAKTNTFC--- 540
GHIK+ DFG+C +++M + + C
Sbjct: 916 DIKPDNILIDRNGHIKLTDFGLCTGFRWTHNSKYYQRDGTHARQDSMEVKCQLDEQCQCE 737
Query: 541 ---------------------GTPDYIAPEIL--LGQKYNHSVDWWSFGVLLYEMLIGQS 577
GTP+YIAPE+L LG Y DWWS GV+L+EML+G
Sbjct: 736 ILKPLERRRKREQRCLAHSLVGTPNYIAPEVLSRLG-GYTSVCDWWSVGVILFEMLVGHP 560
Query: 578 PFHGQDEEELFHSIR--MDNPFYPRW--LEKEAKDLLVKLFVREPEKRLGVR--GDIRQH 631
PF+ E + + D PR L + AKDL+++L + RLG+ G+I+ H
Sbjct: 559 PFYANTPAETQYKVINWKDMLKIPRESNLSQPAKDLILRLCC-GSDDRLGLNGAGEIKTH 383
Query: 632 PLFREINWEELERKEIDPPFRPKVKSPFDCSNFD 665
F +N+E L +++ PP+ P ++ D SNFD
Sbjct: 382 MFFAGVNFETLRKQQ--PPYVPNIRYATDTSNFD 287
>00486
Length = 797
Score = 128 bits (322), Expect = 7e-30, Method: Compositional matrix adjust.
Identities = 66/170 (38%), Positives = 96/170 (56%), Gaps = 4/170 (2%)
Frame = -2
Query: 536 TNTFCGTPDYIAPEILLGQKYNHSVDWWSFGVLLYEMLIGQSPFHGQDEEELFHSIRMDN 595
T+TFCGT +Y+APEIL + +VDWWS G L+Y+ML G PF ++ ++ I
Sbjct: 787 THTFCGTIEYMAPEILTRTGHGKAVDWWSLGALMYDMLTGSPPFTAENRKKTIDKILKGK 608
Query: 596 PFYPRWLEKEAKDLLVKLFVREPEKRLGV----RGDIRQHPLFREINWEELERKEIDPPF 651
P +L EA+ L+ KL + P +RLG G I+ H FR NW L + +PPF
Sbjct: 607 LNLPPYLTNEARGLIKKLLRKNPAERLGGGHDDSGPIKDHQFFRNTNWALLALRRAEPPF 428
Query: 652 RPKVKSPFDCSNFDKEFLNEKPRLSFADRALINSMDQNMFRNFSFMNPGM 701
RP V S D S FD +F + P S D L +S++Q +F+ F+++ P +
Sbjct: 427 RPNVTSDEDTSQFDTKFTRQTPVDSPDDTILSDSINQ-VFKGFTYIAPSV 281
>27405
Length = 532
Score = 102 bits (254), Expect = 5e-22, Method: Compositional matrix adjust.
Identities = 59/178 (33%), Positives = 90/178 (50%), Gaps = 4/178 (2%)
Frame = -3
Query: 390 SFGKVFLAEFKKTNQFFAIKAXXXXXXXXXXXXECTMVEKRVLSLAWE---HPFLTHMFC 446
FG+V+ T + +A+K + E+ +LSL PF+ M
Sbjct: 530 GFGEVYGCRKADTGKMYAMKCLDKKRIKMKGGETLALNERIMLSLVSTGEGSPFIVCMTY 351
Query: 447 TFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEIILGLQFLHSKGIVYRXXX 506
FQT E L F+++ +NGGDL YH+ F FYAAE++LGL+ +HS+ +VYR
Sbjct: 350 AFQTPEKLCFILDLMNGGDLHYHLSQHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLK 171
Query: 507 XXXXXXXXXGHIKIADFGMCKENMLGDAKTNTFCGTPDYIAPEILL-GQKYNHSVDWW 563
GH++I+D G+ + K + GT Y+APE+L+ GQ Y+ S DW+
Sbjct: 170 PANILLDENGHVRISDLGLACD--FSKKKPHASVGTHGYMAPEVLMKGQAYDSSADWF 3
>17722
Length = 680
Score = 101 bits (251), Expect = 1e-21, Method: Compositional matrix adjust.
Identities = 54/133 (40%), Positives = 79/133 (59%), Gaps = 5/133 (3%)
Frame = -3
Query: 560 VDWWSFGVLLYEMLIGQSPFHGQDEEELFHSIRMDNPFYPRWLEKEAKDLLVKLFVREPE 619
VDWW GV++YEM+ G+ PF+ +D + LF I + N +PR L +EAK LL L + P+
Sbjct: 678 VDWWGTGVVMYEMMCGRLPFYNRDHDVLFELILLQNVKFPRNLSEEAKTLLSGLLAKNPK 499
Query: 620 KRLGVR----GDIRQHPLFREINWEELERKEIDPPFRPKVKSPFDCSNFDKEFLNEKPRL 675
+RLG +I+ HP F+ INW++L K+I PP++P VKS +D +EF E L
Sbjct: 498 RRLGGSEADVTEIKTHPFFQCINWDDLAAKKITPPWKPDVKSSWDTKYIPEEFAQESLHL 319
Query: 676 SFA-DRALINSMD 687
+ D L +D
Sbjct: 318 TPGHDHPLAERLD 280
>26156
Length = 479
Score = 80.5 bits (197), Expect(2) = 6e-21, Method: Compositional matrix adjust.
Identities = 39/110 (35%), Positives = 61/110 (55%)
Frame = -1
Query: 374 KLKIEDFILHKMLGKGSFGKVFLAEFKKTNQFFAIKAXXXXXXXXXXXXECTMVEKRVLS 433
KL + DF+L +++G+GS+ KV E K+T + +A+K + EK V
Sbjct: 401 KLGLTDFLLLRVIGRGSYAKVLQVEHKRTKRIYAMKVIKKELVNDDEDIDWVQTEKHVFE 222
Query: 434 LAWEHPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATF 483
A +PFL + FQ++ LFFV+E++NGGDLM+H+Q + A F
Sbjct: 221 TATNYPFLVGLHSCFQSESRLFFVIEFVNGGDLMFHMQRQRRLPEEHARF 72
Score = 39.3 bits (90), Expect(2) = 6e-21, Method: Composition-based stats.
Identities = 16/22 (72%), Positives = 18/22 (81%)
Frame = -3
Query: 482 TFYAAEIILGLQFLHSKGIVYR 503
TFY+AEI L L FLH +GIVYR
Sbjct: 78 TFYSAEICLALNFLHKRGIVYR 13
>12721
Length = 821
Score = 96.3 bits (238), Expect = 4e-20, Method: Compositional matrix adjust.
Identities = 71/276 (25%), Positives = 127/276 (46%), Gaps = 13/276 (4%)
Frame = +1
Query: 359 LPEPE-LNKE--RPSLQIKLK-------IEDFILHKMLGKGSFGKVFLAEFKKTNQFFAI 408
+PEP+ L+ E R +LQ+ + ++DF+ +G+GS G V +A + Q A+
Sbjct: 10 MPEPQRLSHEQFRAALQMVVTPGDPRTFLDDFM---KIGEGSTGIVCIATSRDGRQM-AV 177
Query: 409 KAXXXXXXXXXXXXECTMVEKRVLSLAWEHPFLTHMFCTFQTKENLFFVMEYLNGGDLMY 468
K + + V+ + HP + M+ ++ + L+ VME++ GG L
Sbjct: 178 KKMDLRKQQRRE----LLFNEVVVMRDYHHPNIVEMYNSYLVNDELWVVMEFMEGGAL-T 342
Query: 469 HIQSCHKFDLSRATFYAAEIILGLQFLHSKGIVYRXXXXXXXXXXXXGHIKIADFGMCKE 528
I + ++ D + + L FLH+ G+++R G +K+ DFG C +
Sbjct: 343 DIVTNNRMDEVQIATVCRACLKALAFLHANGVIHRDIKSDSILLSHDGKVKLXDFGFCAQ 522
Query: 529 NMLGDAKTNTFCGTPDYIAPEILLGQKYNHSVDWWSFGVLLYEMLIGQSPFHGQDEEELF 588
K + GTP ++APE++ Y VD WS G+++ EM+ + PF + +
Sbjct: 523 VTQDLQKRKSLVGTPYWMAPEVISRLPYGPEVDIWSLGIMVMEMIDAEPPFFNEPPLQAM 702
Query: 589 HSIRMDNPFYPRWLEKEAKDL---LVKLFVREPEKR 621
IR P R K + L + ++ VR+P +R
Sbjct: 703 RRIRDMPPPKLRNTHKISPRLQGFIDRMLVRDPHQR 810
>15910
Length = 1361
Score = 96.3 bits (238), Expect = 4e-20, Method: Compositional matrix adjust.
Identities = 55/161 (34%), Positives = 90/161 (55%), Gaps = 8/161 (4%)
Frame = +2
Query: 477 DLSRATFYAAEIILGLQFLHSKGIVYRXXXXXXXX---XXXXGHIKIADFGMCKENMLGD 533
D +RA ++I+ G+Q++H+ G+V+R +K+ADFG+ + + +
Sbjct: 467 DAARAI---SDILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLADFGLSR-IIEPE 634
Query: 534 AKTNTFCGTPDYIAPEILLGQKYNHSVDWWSFGVLLYEMLIGQSPFHGQDEEELFHSI-- 591
+ +T CGTP Y APE+L G KY SVD WS GV+ Y +L G PF ++E E++ I
Sbjct: 635 VQMSTVCGTPGYCAPEVLKGDKYTPSVDMWSVGVIAYILLCGYEPFFAENEFEMYRKIIK 814
Query: 592 ---RMDNPFYPRWLEKEAKDLLVKLFVREPEKRLGVRGDIR 629
+ D ++ + + AKD++ KL V +P+KRL +R
Sbjct: 815 GEYKFDEEYWSE-ISENAKDVVRKLLVIDPKKRLTATEALR 934
>26560
Length = 398
Score = 94.7 bits (234), Expect = 1e-19, Method: Composition-based stats.
Identities = 46/121 (38%), Positives = 70/121 (57%), Gaps = 1/121 (0%)
Frame = -1
Query: 465 DLMYHIQSCHKFDLSRATFYAAEIILGLQFLHSKGIVYRXXXXXXXXXXXXGHIKIADFG 524
DL YH+ F FYAAE++LGL+ +HS+ +VYR GH++I+D G
Sbjct: 398 DLHYHLSQHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLG 219
Query: 525 MCKENMLGDAKTNTFCGTPDYIAPEILL-GQKYNHSVDWWSFGVLLYEMLIGQSPFHGQD 583
+ + + + GT Y+APE+L+ GQ Y+ S DW+SFG +LY++L G SPF +
Sbjct: 218 LACD--FSKKRPHASVGTHGYMAPEVLMKGQSYDSSADWFSFGCMLYKLLKGHSPFRQHN 45
Query: 584 E 584
+
Sbjct: 44 Q 42
>31885
Length = 529
Score = 90.9 bits (224), Expect = 2e-18, Method: Compositional matrix adjust.
Identities = 51/148 (34%), Positives = 78/148 (52%), Gaps = 5/148 (3%)
Frame = -2
Query: 437 EHPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEIILGLQFLH 496
+HPFL +++ FQ +E+LF V++ GGDL YH+Q F FY ++ L L +L
Sbjct: 498 DHPFLVNLWYAFQDEEDLFMVVDLFLGGDLRYHMQQEVSFREDCVKFYLCQLALVLDYLR 319
Query: 497 SKGIVYRXXXXXXXXXXXXGHIKIADFGMCKENMLGDAKTNTFCGTPDYIAPEIL---LG 553
S+ IV+R GH + DF + + + D + GT Y+APE+ +
Sbjct: 318 SQKIVHRDIKPDNILLDEQGHCHVTDFNIATQ-LEDDELATSTSGTRPYMAPEVYGVAIN 142
Query: 554 QK--YNHSVDWWSFGVLLYEMLIGQSPF 579
++ Y VDWWS GV L+E+L + PF
Sbjct: 141 ERRGYGFPVDWWSLGVSLFELLKKRRPF 58
>14420
Length = 528
Score = 85.5 bits (210), Expect = 6e-17, Method: Compositional matrix adjust.
Identities = 43/148 (29%), Positives = 78/148 (52%), Gaps = 1/148 (0%)
Frame = +2
Query: 437 EHPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHI-QSCHKFDLSRATFYAAEIILGLQFL 495
++P + + ++ E L+ VME+L GG L + ++C D + E + L+FL
Sbjct: 74 QNPNIVNYLDSYLVGEELWVVMEFLAGGSLTDVVTETC--MDEGQIAAVCRECLQALEFL 247
Query: 496 HSKGIVYRXXXXXXXXXXXXGHIKIADFGMCKENMLGDAKTNTFCGTPDYIAPEILLGQK 555
H +++R G +K+ DFG C + +K +T GTP ++APE++ ++
Sbjct: 248 HENQVIHRDIKSDNILLGMDGSVKLTDFGFCAQLSPEQSKRSTMVGTPYWMAPEVVTRKQ 427
Query: 556 YNHSVDWWSFGVLLYEMLIGQSPFHGQD 583
Y +VD WS GV+ EM+ G+ P+ ++
Sbjct: 428 YGPTVDIWSLGVMCIEMIEGEPPYLNEN 511
>18921
Length = 697
Score = 84.3 bits (207), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 55/198 (27%), Positives = 95/198 (47%), Gaps = 4/198 (2%)
Frame = +2
Query: 386 LGKGSFGKVFLAEFKKTNQFFAIKAXXXXXXXXXXXXECTMVEKRVLSLAWEHPFLTHMF 445
LG+GS+G VF + K+T Q AIK E +++++ + ++ +
Sbjct: 53 LGEGSYGSVFKSLHKETGQVLAIKQVPVDTDLQEIIKEISIMQQ------CDSKYIVKYY 214
Query: 446 CTFQTKENLFFVMEYLNGG---DLM-YHIQSCHKFDLSRATFYAAEIILGLQFLHSKGIV 501
++ +L+ VMEY G D+M ++ + +++ +Y + GL +LHS+ +
Sbjct: 215 GSYFKNTDLWIVMEYCGAGSVSDIMRLRNKTLVEREIATILYYTLK---GLXYLHSRRKI 385
Query: 502 YRXXXXXXXXXXXXGHIKIADFGMCKENMLGDAKTNTFCGTPDYIAPEILLGQKYNHSVD 561
+R GH K+ADFG+ + AK NT GTP ++APE++ Y+ D
Sbjct: 386 HRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTPYWMAPEVIQEIGYDCVAD 565
Query: 562 WWSFGVLLYEMLIGQSPF 579
WS G+ EM G+ P
Sbjct: 566 IWSLGITALEMAEGKPPV 619
>25445
Length = 460
Score = 83.2 bits (204), Expect = 3e-16, Method: Composition-based stats.
Identities = 32/54 (59%), Positives = 41/54 (75%)
Frame = -1
Query: 232 HRFKVYNYKSPTFCEHCGTLLWGLARQGLKCDACGMNVHHRCQTKVANLCGINQ 285
H+FK + Y SPTFC+HCG+LL+GL QGLKCD+C MN H RC+ V LCG++
Sbjct: 397 HKFKAHTYGSPTFCDHCGSLLYGLIHQGLKCDSCDMNCHKRCEKHVPRLCGMDH 236
Score = 45.1 bits (105), Expect = 1e-04, Method: Composition-based stats.
Identities = 19/50 (38%), Positives = 26/50 (52%)
Frame = -1
Query: 160 HEFTATFFPQPTFCSVCHEFVWGLNKQGYQCRQCNAAIHKKCIDKVIAKC 209
H+F A + PTFC C ++GL QG +C C+ HK+C V C
Sbjct: 397 HKFKAHTYGSPTFCDHCGSLLYGLIHQGLKCDSCDMNCHKRCEKHVPRLC 248
>06405
Length = 1965
Score = 82.4 bits (202), Expect = 5e-16, Method: Compositional matrix adjust.
Identities = 54/228 (23%), Positives = 104/228 (45%), Gaps = 10/228 (4%)
Frame = +1
Query: 379 DFILHKMLGKGSFGKVFLAEFKKTNQFFAIKAXXXXXXXXXXXXECTMVEKRVLSLAWEH 438
+ + LG G +G V+ A +K+ N+ A+K E + K + +H
Sbjct: 262 EIAMKHRLGGGQYGDVYEAMWKRYNKIVAVKTLKEDTMALNDFLEEAAIMKEM-----KH 426
Query: 439 PFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFD--LSRATFYAAEIILGLQFLH 496
P L + + + V E++ G+L+ +++S + + + + A +I G+ +L
Sbjct: 427 PNLVQLLGVCTREPPFYIVTEFMPHGNLLDYLRSSTREENGPTALMYMATQIASGMAYLE 606
Query: 497 SKGIVYRXXXXXXXXXXXXGHIKIADFGMCKENMLGDAKTNTFCGTP---DYIAPEILLG 553
+K ++R +K+ADFG+ + ++ D G + APE L
Sbjct: 607 TKNFIHRDLAARNCLVADSNMVKVADFGLAR--LMKDDTYTAHIGAKFPIKWTAPEGLAF 780
Query: 554 QKYNHSVDWWSFGVLLYEMLI-GQSPFHGQDEEELFHSI----RMDNP 596
+++ D W+FGVLL+E+ G SP+ G + E++H + RM+ P
Sbjct: 781 NRFSTRSDIWAFGVLLWELATYGMSPYPGVELTEVYHLLERGYRMERP 924
>00300
Length = 2318
Score = 82.4 bits (202), Expect = 5e-16, Method: Compositional matrix adjust.
Identities = 63/246 (25%), Positives = 101/246 (41%), Gaps = 10/246 (4%)
Frame = -1
Query: 386 LGKGSFGKVFLAEFKKTNQFFAIKAXXXXXXXXXXXXECTMVEKRVLSLAWEHPFLTHMF 445
+G+G FGKV+ A T + A+K E M ++ + +H L +
Sbjct: 1634 IGEGQFGKVYTAVNMSTGELMALKEMKFQPNDLQQLRE--MCDEIKIFEGIQHENLVKYY 1461
Query: 446 CTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATF--YAAEIILGLQFLHSKGIVYR 503
K+ + MEY + G I+ K L Y EI+L + LH IV+R
Sbjct: 1460 GVEVHKDEMLMFMEYCDTGT----IEEAAKMGLPEYLIRRYTREIVLAVNHLHENSIVHR 1293
Query: 504 XXXXXXXXXXXXGHIKIADFG---MCKENMLGDAKTNTFCGTPDYIAPEILLGQK---YN 557
GH+K+ DFG K + + + GT Y+APE+ Y
Sbjct: 1292 DIKGANIFLTSNGHVKLGDFGCSVKLKSHTTMPGEFHNLVGTTAYMAPEVFTQNDQGGYG 1113
Query: 558 HSVDWWSFGVLLYEMLIGQSPFHGQDEE-ELFHSIRMDN-PFYPRWLEKEAKDLLVKLFV 615
+ D WS G ++ EM G+ P+H D ++ + + + + P P L E K L +
Sbjct: 1112 RAADIWSLGCVVIEMATGKRPWHDLDNNYQIMYKVGIGHKPAVPDSLSVEGKHFLDLIMC 933
Query: 616 REPEKR 621
+P +R
Sbjct: 932 HDPAQR 915
>09606
Length = 1300
Score = 78.6 bits (192), Expect = 8e-15, Method: Compositional matrix adjust.
Identities = 59/229 (25%), Positives = 96/229 (41%), Gaps = 22/229 (9%)
Frame = -3
Query: 376 KIEDFILHKMLGKGSFGKVFLAEFKKTNQFFAIKAXXXXXXXXXXXXECTMVEKRVLSLA 435
++E+F+L++ LGKG ++ K T F AI E T + ++
Sbjct: 1121 RMENFVLYEELGKGEHSIIYKGRRKGTINFVAIHCIEKCKRP-----EVTNTVRMTHDIS 957
Query: 436 WEHPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEIILGLQFL 495
HP + ++T +L+ V+E GG L + H + + ++ GL ++
Sbjct: 956 --HPNVVQFHEWYETSNHLWLVVELCTGGSLADILAQDHHLPETSIRDFGIHLVTGLHYI 783
Query: 496 HSKGIVYRXXXXXXXXXXXXGHIKIADFGMCK---ENM---------LGD---------- 533
HS GI++ G +K ADFG+ K EN+ GD
Sbjct: 782 HSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQWNIQSAEEM 603
Query: 534 AKTNTFCGTPDYIAPEILLGQKYNHSVDWWSFGVLLYEMLIGQSPFHGQ 582
K G+P Y+APE+ G + + D W+ G + YEM G PF G+
Sbjct: 602 MKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSGHPPFLGE 456
>01060
Length = 1800
Score = 77.4 bits (189), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 64/235 (27%), Positives = 100/235 (42%), Gaps = 4/235 (1%)
Frame = +1
Query: 363 ELNKERPSLQIKLKIEDFILHKMLGKGSFGKVFLAEFKKTNQFFAIKAXXXXXXXXXXXX 422
+LN +R + + + D + +G+G++G V+ + T + A+K
Sbjct: 28 KLNIKRLMMDFETALSDLTDFQKIGEGTYGVVYKCRHRATGRKLAMKKIRLRGSEDGV-- 201
Query: 423 ECTMVEKRVLSLAWEHPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRAT 482
+ + + + H + + E LF V E+L+ MY + L R
Sbjct: 202 PSSAIREIAMLRELRHTNIVCLEDVIMEDERLFLVFEFLSMDLKMYIDKFPEGVVLDRRL 381
Query: 483 F--YAAEIILGLQFLHSKGIVYRXXXXXXXXXXXXGHIKIADFGMCKENMLGDAKTNTFC 540
Y +I+ G+ F H + IV+R G IKIADFGM + L
Sbjct: 382 VKSYVFQIVTGIXFCHQRRIVHRDLKPQNLLINHTGAIKIADFGMARTFALPVRAYTHEV 561
Query: 541 GTPDYIAPEILLG-QKYNHSVDWWSFGVLLYEMLIGQSPFHGQDE-EELFHSIRM 593
T Y APEIL+G KY+ VD WS G + +MLI F G E ++LF R+
Sbjct: 562 VTLWYRAPEILMGASKYSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRI 726
>21433
Length = 590
Score = 62.4 bits (150), Expect(2) = 6e-14, Method: Composition-based stats.
Identities = 33/100 (33%), Positives = 52/100 (52%)
Frame = +2
Query: 480 RATFYAAEIILGLQFLHSKGIVYRXXXXXXXXXXXXGHIKIADFGMCKENMLGDAKTNTF 539
R Y ++ L++ H + +++R G +KIADFG ++ T
Sbjct: 170 RTACYIYQLSSALEYCHYRKVIHRDIKPENLLLGLKGDLKIADFGWSVH--APSSRRTTM 343
Query: 540 CGTPDYIAPEILLGQKYNHSVDWWSFGVLLYEMLIGQSPF 579
CGT DY+ PE++ G+ ++ +VD WS GVL YE L+G P
Sbjct: 344 CGTLDYLPPEMVEGKTHDENVDLWSLGVLCYEFLVGTPPL 463
Score = 33.9 bits (76), Expect(2) = 6e-14, Method: Compositional matrix adjust.
Identities = 14/40 (35%), Positives = 22/40 (55%)
Frame = +3
Query: 438 HPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFD 477
H + MF F K ++ ++E+ G+L +Q CHKFD
Sbjct: 45 HDNILRMFGYFHDKTRVYLILEFAPKGELYKELQRCHKFD 164
>01707
Length = 757
Score = 74.3 bits (181), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 61/224 (27%), Positives = 103/224 (45%), Gaps = 6/224 (2%)
Frame = +1
Query: 386 LGKGSFGKVFLAEFKKTNQFFAIKAXXXXXXXXXXXXECTMVEKRVLSLAWEHPFLTHMF 445
+G+GS+G VF K+T+Q AIK + M E R+L +HP L +
Sbjct: 88 IGEGSYGVVFKCRNKETSQLVAIKK-FVESEDDPLIKKIAMREIRMLK-QLKHPNLVRLI 261
Query: 446 CTFQTKENLFFVMEYLNG---GDLMYHIQSCHKFDLSRATFYAAEIILGLQFLHSKGIVY 502
F+ K+ L V +Y++ +L + + + + R + + +L + F H ++
Sbjct: 262 EVFRRKKRLHLVFDYVDHTLLNELDRYPRGLPEPMVKRIIY---QTLLAVNFCHQYNTIH 432
Query: 503 RXXXXXXXXXXXXGHIKIADFGMCK-ENMLGDAKTNTFCGTPDYIAPEILLGQ-KYNHSV 560
R G +K+ DFG + GD T+ + T Y APE+L+G +Y V
Sbjct: 433 RDVKPENILITRQGQVKLCDFGFARILTGPGDEYTD-YVATRWYRAPELLVGDTQYGPPV 609
Query: 561 DWWSFGVLLYEMLIGQSPFHGQDEEELFHSIRMD-NPFYPRWLE 603
D W+ G + E+L GQ+ + G+ + + H IR PR +E
Sbjct: 610 DVWAIGCVFAELLTGQALWPGRSDVDQLHLIRKTLGDLIPRHIE 741
>01392
Length = 1806
Score = 73.6 bits (179), Expect = 3e-13, Method: Compositional matrix adjust.
Identities = 58/184 (31%), Positives = 83/184 (45%), Gaps = 32/184 (17%)
Frame = -1
Query: 481 ATFYAAEIILGLQFLHSKGIVYRXXXXXXXXXXXXGHI---KIADFGM-----CKENMLG 532
A+ I L FLHSKGI +R + KI DF + C +
Sbjct: 1785 ASLVVRHIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGISCDGDGTK 1606
Query: 533 DAKTNTFCGTPDYIAPEIL---LGQK--YNHSVDWWSFGVLLYEMLIGQSPFHGQDEEE- 586
+ T G+ +Y+APE++ +G Y+ D WS G++LY ML G PF+GQ E+
Sbjct: 1605 TPELLTPVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILYIMLCGYPPFYGQCGEDC 1426
Query: 587 --------------LFHSIRMDNPFYP--RW--LEKEAKDLLVKLFVREPEKRLGVRGDI 628
LF+SI+ + +P W + AKDL+ L VREP KR D+
Sbjct: 1425 GWNRGEACHDCQDMLFNSIQDGHYKFPSQEWTSISSSAKDLIRHLLVREPRKRYSA-ADV 1249
Query: 629 RQHP 632
+HP
Sbjct: 1248 LKHP 1237
>13212
Length = 1067
Score = 72.0 bits (175), Expect = 9e-13, Method: Compositional matrix adjust.
Identities = 44/157 (28%), Positives = 70/157 (44%), Gaps = 8/157 (5%)
Frame = -1
Query: 487 EIILGLQFLHSKGIVYRXXXXXXXXXXXXGHIKIADFGMCKENMLGDAKTNTFCGTPDYI 546
E+ + L FLH +++R G +K+ADFG+ +N K +TF GTP ++
Sbjct: 956 EMCMALDFLHRHHVIHRDIKAGNVLLTIDGEVKLADFGVSAKNTQTQQKRDTFIGTPYWM 777
Query: 547 APEILL-----GQKYNHSVDWWSFGVLLYEMLIGQSPFHGQDEEELFHSIRMDNPFY--- 598
APE++L Y+ D WS GV L E + P + I +P
Sbjct: 776 APEVVLCETLKDTPYDFKADIWSLGVTLIEFAQIEPPNKEMHPMRVLIKIHKSDPPTLEK 597
Query: 599 PRWLEKEAKDLLVKLFVREPEKRLGVRGDIRQHPLFR 635
P+ K KD + K V++P R ++ +HP +
Sbjct: 596 PKKWTKLFKDFIAKCLVKDPNLR-PTAAELLEHPFMK 489
>14126
Length = 1265
Score = 70.5 bits (171), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 74/292 (25%), Positives = 124/292 (42%), Gaps = 40/292 (13%)
Frame = +3
Query: 385 MLGKGSFGKVFLA-EFKKTNQFFAIKAXXXXXXXXXXXXECTMVEKRVLSL-----AWEH 438
++G G++G V+ A + + +F A+K M+ R +S+ +EH
Sbjct: 210 VIGNGAYGTVYKARDLRNQGEFVAMKRIRLNNTEEG----MPMMAIREISMLKQLEQYEH 377
Query: 439 PFLTHMF----CTFQTKE-NLFFVMEYLNGGDLMYHIQSCHKFDLS--RATFYAAEIILG 491
P + + T +E L V EY+ DL ++ C L R +++ G
Sbjct: 378 PNVVRLLDVSHNTITDREIRLNLVFEYIEH-DLATYLAKCPSPGLGPDRIKDLMLQLLNG 554
Query: 492 LQFLHSKGIVYRXXXXXXXXXXXXGHIKIADFGMCKENMLGDAKTNTFCGTPDYIAPEIL 551
+ FLHS IV+R G +K+ADFG+ + A T T T Y +PE+L
Sbjct: 555 VDFLHSNRIVHRDLKPQNLLISKDGRLKLADFGLARIYSFHMALT-TVVVTLWYRSPEVL 731
Query: 552 LGQKYNHSVDWWSFGVLLYEMLIGQSPFHGQDE----EELFHSIRM-------------D 594
+ +Y SVD WS G + E+ ++ F G E +++F I +
Sbjct: 732 MQAEYGTSVDIWSCGCIFAELFTRRALFKGSSEFDQLKKIFEVIGLPPAGDWPEGVSVHR 911
Query: 595 NPFYPR----------WLEKEAKDLLVKLFVREPEKRLGVRGDIRQHPLFRE 636
N F P ++ +AKDL+ K+ V + +R+ R + HP R+
Sbjct: 912 NSFRPTPPVPLQTLVPEMDPQAKDLMEKMLVFKSGRRISSRESL-LHPYLRD 1064
>25019
Length = 730
Score = 70.5 bits (171), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 28/51 (54%), Positives = 37/51 (72%)
Frame = +3
Query: 516 GHIKIADFGMCKENMLGDAKTNTFCGTPDYIAPEILLGQKYNHSVDWWSFG 566
GH+K+ DFG+CKE + G T+TFCGT +Y+APEIL + +VDWWS G
Sbjct: 285 GHVKLTDFGLCKEAITGTRVTHTFCGTIEYMAPEILTRTGHGKAVDWWSLG 437
>11353
Length = 454
Score = 67.0 bits (162), Expect = 2e-11, Method: Composition-based stats.
Identities = 30/91 (32%), Positives = 46/91 (50%)
Frame = +1
Query: 191 RQCNAAIHKKCIDKVIAKCTGSAINSRETMFHKERFKIDMPHRFKVYNYKSPTFCEHCGT 250
R ++HK+ +++ + G + MF + PHRF+ Y Y +PT+C+ C
Sbjct: 46 RSHGRSVHKRSTLEILVR--GKMLGEAARMFSQ-------PHRFEKYTYTTPTYCDFCQQ 198
Query: 251 LLWGLARQGLKCDACGMNVHHRCQTKVANLC 281
LLWG ++ G C CG N H +CQ V C
Sbjct: 199 LLWGFSKTGTHCVDCGYNCHDKCQPLVPKTC 291
Score = 45.8 bits (107), Expect = 6e-05, Method: Composition-based stats.
Identities = 17/51 (33%), Positives = 23/51 (45%)
Frame = +1
Query: 160 HEFTATFFPQPTFCSVCHEFVWGLNKQGYQCRQCNAAIHKKCIDKVIAKCT 210
H F + PT+C C + +WG +K G C C H KC V C+
Sbjct: 142 HRFEKYTYTTPTYCDFCQQLLWGFSKTGTHCVDCGYNCHDKCQPLVPKTCS 294
>21079
Length = 878
Score = 65.5 bits (158), Expect = 7e-11, Method: Compositional matrix adjust.
Identities = 42/145 (28%), Positives = 71/145 (48%), Gaps = 4/145 (2%)
Frame = +1
Query: 438 HPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSR--ATFYAAEIILGLQFL 495
HP L ++ F+ + VME++ G+L + F L+ + +I G+ ++
Sbjct: 1 HPKLLMLWDAFEAPRTMVLVMEFVGAGELFERVIR-DDFVLTERDCVHFVRQICSGVGYM 177
Query: 496 HSKGIVYRXXXXXXX--XXXXXGHIKIADFGMCKENMLGDAKTNTFCGTPDYIAPEILLG 553
H++ I++ IKI DFG+ + GD+ F GTP++IAPE++
Sbjct: 178 HTQSILHLDLKPENVLCVSDNSNQIKIIDFGLARFYKPGDSLQVLF-GTPEFIAPEVVNY 354
Query: 554 QKYNHSVDWWSFGVLLYEMLIGQSP 578
+ N + D WS GV+ Y +L G SP
Sbjct: 355 DEINFTTDMWSIGVICYILLSGLSP 429
>38560
Length = 479
Score = 63.5 bits (153), Expect = 3e-10, Method: Composition-based stats.
Identities = 37/121 (30%), Positives = 55/121 (45%), Gaps = 5/121 (4%)
Frame = -3
Query: 533 DAKTNTFCGTPDYIAPEILLGQKY-NHSVDWWSFGVLLYEMLIGQSPFHGQDEEELFHSI 591
D T CG+P Y APE++ G +Y D WS GVLLY +L G PF + L
Sbjct: 423 DHHLTTCCGSPAYAAPELISGLEYLGSEADIWSMGVLLYALLCGYLPFDDEKXSHL*QKN 244
Query: 592 RMDNPFYPRWLEKEAKDLLVKLFVREPEKRLGVRGDIRQHPLFREIN----WEELERKEI 647
+ P WL ++ LL + +P R+ +R + H L + N W ++ +
Sbjct: 243 QKRKDEVPEWLSEDTTKLLEGMLQTDPSHRITIRRLLDHHWLNQGFNVPVEWASKYKRTL 64
Query: 648 D 648
D
Sbjct: 63 D 61
>13592
Length = 980
Score = 63.2 bits (152), Expect = 3e-10, Method: Compositional matrix adjust.
Identities = 55/246 (22%), Positives = 99/246 (40%), Gaps = 9/246 (3%)
Frame = +2
Query: 386 LGKGSFGKVFLAEFKKTNQFFAIKAXXXXXXXXXXXXECTMVEKRVLSLAWEHPFLTHMF 445
+G+G FGKV+ A T + A+K + E+ + +H L +
Sbjct: 8 IGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETRALK--NVAEELKILEGIKHKNLVRYY 181
Query: 446 CTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEIILGLQFLHSKGIVYRXX 505
+E L ME + G L ++ + + + A+++ G+ LH GIV+R
Sbjct: 182 GIEVHREELLIFMELCSEGTLESLVELTGGLPEALSRRFTAQLLSGVAELHKHGIVHRDI 361
Query: 506 XXXXXXXXXXGH-IKIADFGMC---KENMLGDAKTNTFCGTPDYIAPEILL---GQKYNH 558
+ +K+ DFG + + + + GT Y+APE+ +
Sbjct: 362 KTANIFLVDGSNSLKLGDFGSAVKIQAHTTVPGELQGYVGTQAYMAPEVFTKTNSDGHGR 541
Query: 559 SVDWWSFGVLLYEMLIGQSPFHGQDE--EELFHSIRMDNPFYPRWLEKEAKDLLVKLFVR 616
D WS G ++ EM G+ P+ D + +F + P P L +E D +
Sbjct: 542 LADIWSVGCVVVEMASGKRPWAQFDSNFQIMFKVGMGEKPQAPESLSQEGHDFIDHCLQH 721
Query: 617 EPEKRL 622
+P++RL
Sbjct: 722 DPKQRL 739
>22804
Length = 967
Score = 62.8 bits (151), Expect = 4e-10, Method: Compositional matrix adjust.
Identities = 29/87 (33%), Positives = 44/87 (50%)
Frame = -3
Query: 196 AIHKKCIDKVIAKCTGSAINSRETMFHKERFKIDMPHRFKVYNYKSPTFCEHCGTLLWGL 255
++HK+ +++ + G + MF PHRF+ Y Y +PT+C+ C LLWG
Sbjct: 911 SVHKRSTLEILVR--GKMLGEAARMF-------SQPHRFEKYTYTTPTYCDFCQQLLWGF 759
Query: 256 ARQGLKCDACGMNVHHRCQTKVANLCG 282
++ G C CG N H +CQ V C
Sbjct: 758 SKTGTHCVDCGYNCHDKCQPLVPKTCS 678
Score = 43.5 bits (101), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 18/53 (33%), Positives = 24/53 (45%)
Frame = -3
Query: 160 HEFTATFFPQPTFCSVCHEFVWGLNKQGYQCRQCNAAIHKKCIDKVIAKCTGS 212
H F + PT+C C + +WG +K G C C H KC V C+ S
Sbjct: 830 HRFEKYTYTTPTYCDFCQQLLWGFSKTGTHCVDCGYNCHDKCQPLVPKTCSKS 672
>21808
Length = 1011
Score = 62.4 bits (150), Expect = 6e-10, Method: Compositional matrix adjust.
Identities = 48/199 (24%), Positives = 81/199 (40%), Gaps = 13/199 (6%)
Frame = +1
Query: 438 HPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHK-FDLSRATFYAAEIILGLQFLH 496
HP L ++ + +F + E + G L+ +Q + L A+I G+ +L
Sbjct: 109 HPKLIQLYAVCTQDDPIFIITELMKNGSLLEFLQGKGRVLKLPALIDIGAQIACGMAYLE 288
Query: 497 SKGIVYRXXXXXXXXXXXXGHIKIADFGMCKENMLGDAKTNTFCGTP-DYIAPEILLGQK 555
S+ ++R +KIADFG+ + + + P + APE +
Sbjct: 289 SQNYIHRDLAARNILVSDNNTVKIADFGLARVIKEDEYEARVGARFPIKWTAPEAANYNR 468
Query: 556 YNHSVDWWSFGVLLYEMLI-GQSPFHGQDEEELFHSI----RM------DNPFYPRWLEK 604
+ D WSFG+LL E + G+ P+ G E+ H + RM P Y LE
Sbjct: 469 FTIKSDVWSFGILLTETVTYGRVPYPGMTNAEVLHQVEHGYRMPCPPGCPKPLYDIMLEC 648
Query: 605 EAKDLLVKLFVREPEKRLG 623
K+ + + +R P G
Sbjct: 649 WRKEEMERPHLRNPAMEAG 705
>13066
Length = 551
Score = 61.6 bits (148), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 37/134 (27%), Positives = 58/134 (43%), Gaps = 4/134 (2%)
Frame = +3
Query: 437 EHPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEIILGLQFLH 496
+HP++ + Q F M + GDL+ +IQ +A + ++ L +LH
Sbjct: 150 DHPYIIQIHSILQRXPKNFIFMRFAERGDLLTYIQEVGFVKEKQAKIWFYQMTTALNYLH 329
Query: 497 SKGIVYRXXXXXXXXXXXXGHIKIADFGM---CKENMLGDAKTNTFCGTPDYIAPEILLG 553
S + +R ++K+ADFG C + T+CG+ Y APEI+ G
Sbjct: 330 SYDVAHRDLKCENILLSSHFNVKLADFGFACACITESGEKYMSRTYCGSAAYAAPEIVYG 509
Query: 554 QKYNHSV-DWWSFG 566
Y V D WS G
Sbjct: 510 APYAPKVADAWSLG 551
>19361
Length = 685
Score = 60.5 bits (145), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 24/58 (41%), Positives = 33/58 (56%)
Frame = -1
Query: 231 PHRFKVYNYKSPTFCEHCGTLLWGLARQGLKCDACGMNVHHRCQTKVANLCGINQKLM 288
PH FKV N+ +CE C +WGL QG+KC CG+ H +C ++ N C N K +
Sbjct: 319 PHVFKVQNFNGLNWCELCANFMWGLIAQGVKCQDCGVQTHKKCSERMPNECMPNMKYV 146
Score = 46.2 bits (108), Expect = 4e-05, Method: Compositional matrix adjust.
Identities = 25/95 (26%), Positives = 40/95 (42%)
Frame = -1
Query: 154 VHHVKCHEFTATFFPQPTFCSVCHEFVWGLNKQGYQCRQCNAAIHKKCIDKVIAKCTGSA 213
+ K H F F +C +C F+WGL QG +C+ C HKKC +++ +C +
Sbjct: 334 TQYEKPHVFKVQNFNGLNWCELCANFMWGLIAQGVKCQDCGVQTHKKCSERMPNECMPNM 155
Query: 214 INSRETMFHKERFKIDMPHRFKVYNYKSPTFCEHC 248
+ K + +D+ K P E C
Sbjct: 154 ------KYVKRLYGVDLTTVTKANKQILPIVVEXC 68
>01756
Length = 1858
Score = 59.3 bits (142), Expect = 6e-09, Method: Compositional matrix adjust.
Identities = 53/213 (24%), Positives = 90/213 (42%), Gaps = 13/213 (6%)
Frame = -3
Query: 386 LGKGSFGKVFLAEFKKTNQFFAIKAXXXXXXXXXXXXECTMVEKRVLSLAWEHPF--LTH 443
+G+G+FG+VF A KKT Q A+K + E ++L L L
Sbjct: 1718 IGQGTFGEVFKARCKKTKQVVAMKKVLMDNEKEGFPI-TALREIKILQLLNHENVVDLIE 1542
Query: 444 MFCTFQTKENLFFVMEYL-------NGGDLMYHIQSCHKFDLSRATFYAAEIILGLQFLH 496
+ T T N + M YL + L+ ++ F+L +++ GL ++H
Sbjct: 1541 ICSTKATSANRYKSMFYLVFEFCEHDLAGLLSNMSVV--FNLPEIKEVMKQLMNGLYYIH 1368
Query: 497 SKGIVYRXXXXXXXXXXXXGHIKIADFGMCKENMLGDAKTNTFCG---TPDYIAPEILLG 553
I++R G +K+ADFG+ + + + N + T Y PE+LLG
Sbjct: 1367 RNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRPPELLLG 1188
Query: 554 QK-YNHSVDWWSFGVLLYEMLIGQSPFHGQDEE 585
+ Y+ ++D W G ++ EM G E+
Sbjct: 1187 DRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQ 1089
>17591
Length = 474
Score = 52.4 bits (124), Expect(2) = 6e-09, Method: Composition-based stats.
Identities = 23/59 (38%), Positives = 35/59 (59%), Gaps = 3/59 (5%)
Frame = +3
Query: 616 REPEKRLGVRGD---IRQHPLFREINWEELERKEIDPPFRPKVKSPFDCSNFDKEFLNE 671
R E+RLG + D I++ F +INW++L K++ PP+ P V D +FD EF+ E
Sbjct: 141 RRKEERLGAKRDFEEIQEKAFFADINWDDLYNKKVQPPYNPNVSGQLDLRHFDPEFVRE 317
Score = 26.6 bits (57), Expect(2) = 6e-09, Method: Composition-based stats.
Identities = 9/22 (40%), Positives = 15/22 (68%)
Frame = +2
Query: 570 YEMLIGQSPFHGQDEEELFHSI 591
+EML G PF+ +D E++ +I
Sbjct: 2 FEMLYGLPPFYSRDTSEMYENI 67
>17932
Length = 597
Score = 43.1 bits (100), Expect(2) = 9e-09, Method: Composition-based stats.
Identities = 30/94 (31%), Positives = 53/94 (56%)
Frame = -3
Query: 602 LEKEAKDLLVKLFVREPEKRLGVRGDIRQHPLFREINWEELERKEIDPPFRPKVKSPFDC 661
+ KEA+DL+ +L + + + RLG +++QHP F+ ++W + + PP+ P + S D
Sbjct: 460 VSKEARDLISQL-LSDGKSRLG-WPELQQHPFFKTVDWANI--RNAMPPYVPSISSLDDT 293
Query: 662 SNFDKEFLNEKPRLSFADRALINSMDQNMFRNFS 695
S+FD+ EK R + I+S Q R+F+
Sbjct: 292 SHFDEV---EKARPA----PNIDSFHQPSSRDFT 212
Score = 35.0 bits (79), Expect(2) = 9e-09, Method: Composition-based stats.
Identities = 13/22 (59%), Positives = 14/22 (63%)
Frame = -2
Query: 562 WWSFGVLLYEMLIGQSPFHGQD 583
WWS GV YEML G +PF D
Sbjct: 596 WWSLGVCAYEMLFGCTPFTDDD 531
>32957
Length = 645
Score = 58.2 bits (139), Expect = 1e-08, Method: Composition-based stats.
Identities = 26/58 (44%), Positives = 36/58 (62%)
Frame = +3
Query: 523 FGMCKENMLGDAKTNTFCGTPDYIAPEILLGQKYNHSVDWWSFGVLLYEMLIGQSPFH 580
F +C E G +T TFCGT +Y+APE+ ++Y VDWW G+LL+E+L Q H
Sbjct: 3 FALCVEKSGG--RTRTFCGTREYMAPEVHERKEYGKEVDWWGLGILLHELLAAQIKKH 170
>04852
Length = 1462
Score = 57.8 bits (138), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 38/120 (31%), Positives = 57/120 (47%), Gaps = 3/120 (2%)
Frame = +1
Query: 484 YAAEIILGLQFLHSKGIVYRXXXXXXXXXXXXGHIKIADFGMCKENMLGDAKTNTFCGT- 542
YA +I G++FL S+ ++R +KIADFG+ + GD G
Sbjct: 340 YAFQIARGMEFLASRKCIHRDLAARNVLVTEEHVLKIADFGLSRT---GDYYKKRSGGRL 510
Query: 543 -PDYIAPEILLGQKYNHSVDWWSFGVLLYEML-IGQSPFHGQDEEELFHSIRMDNPFYPR 600
++APE L +Y D WSFGV+L+E+ +G P+ EEL+ + D PR
Sbjct: 511 PVKWMAPEALFDMRYTTKSDVWSFGVVLWEIFSLGGMPYASIPNEELYSKLLDDAYRMPR 690
>07940
Length = 1336
Score = 57.8 bits (138), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 35/109 (32%), Positives = 56/109 (51%), Gaps = 3/109 (2%)
Frame = -3
Query: 484 YAAEIILGLQFLHSKGIVYRXXXXXXXXXXXXGHIKIADFGMCKENMLGDAKTNTFCGT- 542
YA ++ G+++L SK ++R +KIADFG+ + D T G
Sbjct: 332 YAYQVARGMEYLASKQCIHRDLAARNVLVAEEYVLKIADFGLTRNLQQFDYYRKTTDGRL 153
Query: 543 -PDYIAPEILLGQKYNHSVDWWSFGVLLYEML-IGQSPFHGQDEEELFH 589
++APE L +KY D WS+GVLL+E+ +G +P+ E+LF+
Sbjct: 152 PVKWMAPEALFDRKYTSKSDVWSYGVLLWEIFTLGGNPYPSVPVEDLFN 6
>19094
Length = 898
Score = 57.0 bits (136), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 31/86 (36%), Positives = 44/86 (51%)
Frame = +1
Query: 491 GLQFLHSKGIVYRXXXXXXXXXXXXGHIKIADFGMCKENMLGDAKTNTFCGTPDYIAPEI 550
GL +LHS+ ++R GH K+ADFG+ + AK NT GTP ++APE+
Sbjct: 94 GL*YLHSRRKIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTPYWMAPEV 273
Query: 551 LLGQKYNHSVDWWSFGVLLYEMLIGQ 576
+ Y+ D WS G+ EM G
Sbjct: 274 IQEIGYDCVADIWSLGITALEMAEGN 351
>01718
Length = 959
Score = 56.6 bits (135), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 51/221 (23%), Positives = 91/221 (41%), Gaps = 7/221 (3%)
Frame = +3
Query: 359 LPEPELNKERPSLQIKLKIEDFILHKMLGKGSFGKVFLAEFKKTNQFFAIKAXXXXXXXX 418
LP+ R ++ +++DFI K +G G F +VF + T Q A+K
Sbjct: 93 LPKSSCQALRHAVSALTRLDDFICEK-IGAGFFSEVFKVTHRITGQVMALKMNTMTSNRH 269
Query: 419 XXXXECTMVEKRVLSLAWEHPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQS-CHKFD 477
E ++ + +H + + L + EY+ G+L ++ +
Sbjct: 270 NMLREVQLLNR------LQHANILRFMGVCVHEGQLHALTEYIPSGNLEQLLEKKDEELP 431
Query: 478 LSRATFYAAEIILGLQFLHSKGIVYRXXXXXXXXXXXXG----HIKIADFGMCKE--NML 531
++ + GL +LHS ++R H IADFG+ + + L
Sbjct: 432 WTQRIQLTLGLARGLDYLHSTRFIHRDLTSKNILIRREDNHGYHAVIADFGLATKIPDPL 611
Query: 532 GDAKTNTFCGTPDYIAPEILLGQKYNHSVDWWSFGVLLYEM 572
K T G+P ++APE+L G YN D +S G+++ E+
Sbjct: 612 DKEKLPT-VGSPYWMAPEVLNGHFYNERADLFSVGIIMCEI 731
>20152
Length = 445
Score = 55.8 bits (133), Expect = 6e-08, Method: Composition-based stats.
Identities = 33/87 (37%), Positives = 50/87 (57%), Gaps = 2/87 (2%)
Frame = +1
Query: 548 PEILLGQKYNH-SVDWWSFGVLLYEMLIGQSPFHGQDEEELFHSIRMDNPF-YPRWLEKE 605
PEILLG Y+ +VD WS GV+LY +++G++PF ++ E I MD + P + +
Sbjct: 1 PEILLGDSYDAPAVDVWSLGVILYMLVVGEAPFQEANDSETLTMI-MDCRYQIPPHISHK 177
Query: 606 AKDLLVKLFVREPEKRLGVRGDIRQHP 632
+DL+ K+ REP R + I HP
Sbjct: 178 CQDLIEKMLQREPVDRASLP-HILAHP 255
>35187
Length = 593
Score = 55.5 bits (132), Expect = 7e-08, Method: Composition-based stats.
Identities = 33/119 (27%), Positives = 49/119 (41%)
Frame = -3
Query: 156 HVKCHEFTATFFPQPTFCSVCHEFVWGLNKQGYQCRQCNAAIHKKCIDKVIAKCTGSAIN 215
H H FT F +PT+C C + +WGL GY C CN +H +C+ V++ C+ A
Sbjct: 327 HGHGHFFTKKTFHKPTYCHHCTDILWGLIGVGYVCEVCNFVVHDRCMKTVVSPCSSIA-- 154
Query: 216 SRETMFHKERFKIDMPHRFKVYNYKSPTFCEHCGTLLWGLARQGLKCDACGMNVHHRCQ 274
K + H + + FC C L ++C+ C H CQ
Sbjct: 153 -------TYLIKNPVAHCWSEPGHFKRKFCSVCRKRLED--STAIRCEICEYYAHLDCQ 4
Score = 50.1 bits (118), Expect = 3e-06, Method: Composition-based stats.
Identities = 20/50 (40%), Positives = 25/50 (50%)
Frame = -3
Query: 232 HRFKVYNYKSPTFCEHCGTLLWGLARQGLKCDACGMNVHHRCQTKVANLC 281
H F + PT+C HC +LWGL G C+ C VH RC V + C
Sbjct: 315 HFFTKKTFHKPTYCHHCTDILWGLIGVGYVCEVCNFVVHDRCMKTVVSPC 166
>29581
Length = 1278
Score = 55.1 bits (131), Expect = 9e-08, Method: Compositional matrix adjust.
Identities = 38/132 (28%), Positives = 60/132 (45%), Gaps = 1/132 (0%)
Frame = -2
Query: 449 QTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEIILGLQFLHSKGIVYRXXXXX 508
++ ++LF VMEY F S+ +++ GL++LH I++R
Sbjct: 1139 KSLDSLFLVMEYCEQDLASLLDNMPAPFSESQVKCIVLQLLKGLRYLHEAFIIHRDLKVS 960
Query: 509 XXXXXXXGHIKIADFGMCKENMLGDAKTNTFCGTPDYIAPEILLGQK-YNHSVDWWSFGV 567
G +KIADFG+ + T Y APE+L G K ++ ++D WS G
Sbjct: 959 NLLMTDKGCVKIADFGLARNYGKPQKPMTPKVVTLWYRAPELLFGSKTHSTAIDMWSAGC 780
Query: 568 LLYEMLIGQSPF 579
+L E+L G P
Sbjct: 779 ILGELL-GHKPL 747
>04591
Length = 1117
Score = 54.7 bits (130), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 37/137 (27%), Positives = 66/137 (48%), Gaps = 2/137 (1%)
Frame = -2
Query: 451 KENLFFVMEYLNGGDLMYHIQSCH-KFDLSRATFYAAEIILGLQFLHSKGIVYRXXXXXX 509
K + + EY + DL + + KF L+ ++++ GL ++H+K I++R
Sbjct: 981 KSTFYLIFEYCDY-DLAGLLNNLRVKFSLADKKNLMSQLLNGLFYIHTKQILHRDIKAAN 805
Query: 510 XXXXXXGHIKIADFGMCKENMLGDAKTNTFCGTPDYIAPEILLGQK-YNHSVDWWSFGVL 568
G +K+ADFG+ + + TN T Y PE+LLG++ Y +D W G +
Sbjct: 804 ILLTRDGVLKLADFGLSRPWVKSKRLTNRVV-TLWYRPPELLLGEREYGPEIDMWGVGCI 628
Query: 569 LYEMLIGQSPFHGQDEE 585
+ EM + G+ E+
Sbjct: 627 MAEMWSRKPLMQGRSEQ 577
>00392
Length = 668
Score = 52.0 bits (123), Expect = 8e-07, Method: Compositional matrix adjust.
Identities = 33/151 (21%), Positives = 73/151 (48%), Gaps = 8/151 (5%)
Frame = +3
Query: 437 EHPFLTHMFCTFQ-----TKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEIILG 491
+HP + F ++ ++ + V E + G L +++ K ++ + +++ G
Sbjct: 105 QHPNIVRFFDYWEEHNHRNRKVIILVTELMTSGTLKTYLKRFKKPNVKILKNWCRQVLKG 284
Query: 492 LQFLHSKG--IVYRXXX-XXXXXXXXXGHIKIADFGMCKENMLGDAKTNTFCGTPDYIAP 548
L FLH++ +++R G +KI D G+ + + + GTP+++AP
Sbjct: 285 LYFLHTRTPPVIHRDLKCDNIFITGPTGSVKIGDLGLA--TLKNQSFAKSVIGTPEFMAP 458
Query: 549 EILLGQKYNHSVDWWSFGVLLYEMLIGQSPF 579
E + + Y+ +VD ++FG+ + EM + P+
Sbjct: 459 E-MYEEHYDEAVDVYAFGMCMLEMASSEYPY 548
>02638
Length = 1490
Score = 51.2 bits (121), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 28/99 (28%), Positives = 49/99 (49%), Gaps = 5/99 (5%)
Frame = +1
Query: 541 GTPDYIAPEILLGQKYNHSVDWWSFGVLLYEMLIGQSPFHGQDEEELFHSI-----RMDN 595
GT ++APE+L G+ Y + D WS G ++ EM + P++ D I +D
Sbjct: 22 GTIAFMAPEVLRGESYGRACDVWSVGCVMIEMCTCRPPWNSHDISNHLALIFKIASSVDP 201
Query: 596 PFYPRWLEKEAKDLLVKLFVREPEKRLGVRGDIRQHPLF 634
P P + +DL+++ ++ + R + D+ HPLF
Sbjct: 202 PPIPENMSPPVRDLMLRCLEQDSDFRPSAK-DLLMHPLF 315
>12786
Length = 460
Score = 50.4 bits (119), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 34/122 (27%), Positives = 56/122 (45%), Gaps = 24/122 (19%)
Frame = -3
Query: 483 FYAAEIILGLQFLHSKGIVYRXXXXXXXXXXXXGHIKIADFGMCKENMLGDAKTNTF--- 539
FY E++ ++ LH++G+++ G++K+ DFG+ N L KT+
Sbjct: 398 FYWREMLRAVKALHNEGVIH-SDLKPANFMLVAGNLKLIDFGIA--NTLQQDKTSVLKDS 228
Query: 540 -CGTPDYIAPEILLGQ------------------KYNHSV--DWWSFGVLLYEMLIGQSP 578
GTP Y++PE ++ KY V D WS G +LY M+ G++P
Sbjct: 227 RVGTPSYMSPEAIMAACDDSADDSMEEDGHRTKPKYKVGVRSDVWSLGCILYNMVYGRTP 48
Query: 579 FH 580
F
Sbjct: 47 FQ 42
>01966
Length = 1735
Score = 50.4 bits (119), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 39/119 (32%), Positives = 52/119 (43%), Gaps = 2/119 (1%)
Frame = -1
Query: 452 ENLFFVMEYLNGGDLMYHIQSCHKFDLSRATF--YAAEIILGLQFLHSKGIVYRXXXXXX 509
E LF V E+L+ MY + L R Y +I+ G+ F H + IV+R
Sbjct: 1495 ERLFLVFEFLSMDLKMYIDKFPEGVVLDRRLVKSYVFQIVTGINFCHQRRIVHRDLKPQN 1316
Query: 510 XXXXXXGHIKIADFGMCKENMLGDAKTNTFCGTPDYIAPEILLGQKYNHSVDWWSFGVL 568
G IKIADFGM + L T Y APEIL+G + + W+ G L
Sbjct: 1315 LLINHTGAIKIADFGMARTFALPVRAYTHEVVTLWYRAPEILMGPQ--STPPXWTCGAL 1145
Score = 32.0 bits (71), Expect = 0.79, Method: Compositional matrix adjust.
Identities = 16/42 (38%), Positives = 22/42 (52%), Gaps = 1/42 (2%)
Frame = -3
Query: 553 GQKYNHSVDWWSFGVLLYEMLIGQSPFHGQDE-EELFHSIRM 593
KY+ VD WS G + +MLI F G E ++LF R+
Sbjct: 1184 ASKYSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRI 1059
>11185
Length = 473
Score = 49.7 bits (117), Expect = 4e-06, Method: Composition-based stats.
Identities = 30/117 (25%), Positives = 48/117 (41%), Gaps = 25/117 (21%)
Frame = +1
Query: 484 YAAEIILGLQFLHSKGIVYRXXXXXXXXXXXXGHIKIADFGMCK---------------- 527
+ ++ GL ++HS GI++ G +K ADFG+ K
Sbjct: 16 FGIHLVTGLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEA 195
Query: 528 ---------ENMLGDAKTNTFCGTPDYIAPEILLGQKYNHSVDWWSFGVLLYEMLIG 575
E M+ T+ G+P Y+APE+ G + + D W+ G + YEM G
Sbjct: 196 GDQWNIQSAEEMMKQVPTS---GSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSG 357
>29590
Length = 320
Score = 48.5 bits (114), Expect = 8e-06, Method: Composition-based stats.
Identities = 22/41 (53%), Positives = 26/41 (63%)
Frame = +3
Query: 541 GTPDYIAPEILLGQKYNHSVDWWSFGVLLYEMLIGQSPFHG 581
GTPDY+APE+L + + D WS GVL Y ML SPF G
Sbjct: 60 GTPDYVAPEVLDYEPLSIQTDMWSLGVLSYVMLTACSPFVG 182
>14116
Length = 1017
Score = 48.5 bits (114), Expect = 8e-06, Method: Compositional matrix adjust.
Identities = 32/123 (26%), Positives = 58/123 (47%), Gaps = 4/123 (3%)
Frame = -1
Query: 455 FFVMEYLNGGDLMYHIQSC-HKFDLSRATFYAAEIILGLQFLHSKGIVYRXXXXXXXXXX 513
V+ ++ GDL+ +I+ H+ + Y +I G+ +L V+R
Sbjct: 396 LVVLPFMKHGDLLTYIRDDQHQPTIKDLIMYGVDIARGMDYLAGLKFVHRDLAARNCMLD 217
Query: 514 XXGHIKIADFGMCKENMLGD--AKTNTFCGTP-DYIAPEILLGQKYNHSVDWWSFGVLLY 570
H+K+ADFG+ ++ + + N P ++A E L Y+ D WS+GV+L+
Sbjct: 216 EDFHVKVADFGLARDIYEKEYYSSENKKAKLPVKWMALESLEKGNYDSKTDVWSYGVVLW 37
Query: 571 EML 573
E+L
Sbjct: 36 ELL 28
>27546
Length = 426
Score = 48.1 bits (113), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 24/91 (26%), Positives = 41/91 (45%)
Frame = -1
Query: 437 EHPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEIILGLQFLH 496
+HP + + Q +F M Y GD++ HI+ D ++ + ++ LQ+LH
Sbjct: 306 DHPNIIQIHSILQRGPKIFIFMRYAEKGDMLSHIKKTGPIDEAQTKVWFFQMAKALQYLH 127
Query: 497 SKGIVYRXXXXXXXXXXXXGHIKIADFGMCK 527
S I +R ++KIADFG +
Sbjct: 126 SHDIAHRDLKCENILLSKRLNVKIADFGFAR 34
>09007
Length = 1440
Score = 47.8 bits (112), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 39/159 (24%), Positives = 72/159 (45%), Gaps = 13/159 (8%)
Frame = -1
Query: 476 FDLSRATFYAAEIILGLQFLHSKGIVYRXXXXXXXXXXXXGHIKIADFGMCKENMLGDAK 535
F + R ++ ++ G+ +L SK +V+R +KI+D G+ LG K
Sbjct: 573 FSVPRLCDFSQQVCDGMSYLESKRLVHRDLAARNILLFSKSKVKISDVGV--SGALGAGK 400
Query: 536 -------TNTFCGTPDYIAPEILLGQKYNHSVDWWSFGVLLYEMLI-GQSPFHGQDEEEL 587
T + APE ++ + D W+FGVLL+E G P+ G + +++
Sbjct: 399 EYYQSQQTIHLQNAVAWCAPESFRNLCFSSASDVWAFGVLLWEFFTHGFQPWAGLNGQQI 220
Query: 588 FHSIRMDNPFYPRWLE-----KEAKDLLVKLFVREPEKR 621
++ D P R + KE +++K + +EP++R
Sbjct: 219 MEAV--DAPQSQRLEQPDLCPKEYYAVMLKCWEQEPQRR 109
>08294
Length = 1849
Score = 41.6 bits (96), Expect(2) = 4e-05, Method: Compositional matrix adjust.
Identities = 42/207 (20%), Positives = 81/207 (39%), Gaps = 24/207 (11%)
Frame = +2
Query: 439 PFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHK------------FDLSRATFYAA 486
P + H + E F + EY + GDL + + LS+
Sbjct: 887 PNIVHFMGVCREAEPHFLITEYCDWGDLKQFLLATRNDNGRGRGTRVPALALSQKLGMGQ 1066
Query: 487 EIILGLQFLHSKGIVYRXXXXXXXXXXXXGHIKIADFGMCKENMLGDAKTNTFCGTPD-- 544
++ G++ L ++G+V+ +K+A + + GD + +
Sbjct: 1067 QVAAGMEALSNQGLVHGDLAARNVLLTSRMQLKVA-----RPALSGDVYASEYYPLHQRL 1231
Query: 545 ----YIAPEILLGQKYNHSVDWWSFGVLLYEML-IGQSPFHGQDEEELFHSIR-----MD 594
++ PE +L D W+FGV L+E+L + P+ +EE+ S++ +D
Sbjct: 1232 VPLRWLPPEGVLEDSATTCGDVWAFGVFLWEVLQLADLPYRLMSDEEVLRSLQHSQAALD 1411
Query: 595 NPFYPRWLEKEAKDLLVKLFVREPEKR 621
+P P L LL + ++P +R
Sbjct: 1412 SPDAPPAL----LSLLQRCTAQQPSQR 1480
Score = 24.3 bits (51), Expect(2) = 4e-05, Method: Compositional matrix adjust.
Identities = 9/17 (52%), Positives = 12/17 (70%)
Frame = +1
Query: 385 MLGKGSFGKVFLAEFKK 401
++GKG +G VFLA K
Sbjct: 721 IMGKGCYGDVFLARAKS 771
>26711
Length = 405
Score = 45.8 bits (107), Expect = 6e-05, Method: Composition-based stats.
Identities = 28/97 (28%), Positives = 47/97 (48%), Gaps = 2/97 (2%)
Frame = -2
Query: 492 LQFLHSKGIVYRXXXXXXXXXX--XXGHIKIADFGMCKENMLGDAKTNTFCGTPDYIAPE 549
LQ +H++G+V+ +++ DFG+ ++ + +T GTP + +PE
Sbjct: 377 LQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARK-LYPPQETFLNHGTPGFTSPE 201
Query: 550 ILLGQKYNHSVDWWSFGVLLYEMLIGQSPFHGQDEEE 586
L + + + D W GVL Y +L GQSPF E
Sbjct: 200 ALDVKPISTASDVWGVGVLAYILLSGQSPFQADSATE 90
>28638
Length = 1458
Score = 43.9 bits (102), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 24/62 (38%), Positives = 34/62 (54%)
Frame = -1
Query: 518 IKIADFGMCKENMLGDAKTNTFCGTPDYIAPEILLGQKYNHSVDWWSFGVLLYEMLIGQS 577
IKI DFG LG + + + Y +PE+LLG Y+ ++D WS G +L EM G+
Sbjct: 708 IKIVDFG--SSCQLGQ-RIYQYIQSRFYRSPEVLLGVPYDLAIDMWSLGCILVEMHTGEP 538
Query: 578 PF 579
P
Sbjct: 537 PL 532
>04138
Length = 800
Score = 43.5 bits (101), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 26/98 (26%), Positives = 45/98 (45%), Gaps = 4/98 (4%)
Frame = +1
Query: 492 LQFLHSKGIVYRXXXXXXXXXXXXGHIKIADFGMCKENMLGDAKTNTFCG---TPDYIAP 548
L ++H I++R G +K+ADFG+ + + + N + T Y P
Sbjct: 52 LYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRPP 231
Query: 549 EILLGQK-YNHSVDWWSFGVLLYEMLIGQSPFHGQDEE 585
E+LLG + Y+ ++D W G ++ EM G E+
Sbjct: 232 ELLLGDRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQ 345
>19761
Length = 473
Score = 43.5 bits (101), Expect = 3e-04, Method: Composition-based stats.
Identities = 24/78 (30%), Positives = 39/78 (50%), Gaps = 1/78 (1%)
Frame = -3
Query: 496 HSKGIVYRXXXXXXXXXXXXGHIKIADFGMCKENMLGDAKTNTF-CGTPDYIAPEILLGQ 554
H+ I++R G +++ D G+ ++ + G A T GT Y++PEIL Q
Sbjct: 366 HTPVILHRDLKPQNIYVTEKGDVRLGDLGLARK-LTGPADFATSQVGTIMYLSPEILSQQ 190
Query: 555 KYNHSVDWWSFGVLLYEM 572
YN D WS G + Y++
Sbjct: 189 PYNSKSDIWSLGCVFYDI 136
>37602
Length = 804
Score = 43.1 bits (100), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 28/106 (26%), Positives = 45/106 (42%), Gaps = 7/106 (6%)
Frame = -1
Query: 445 FCTFQTKENLFFVMEYLNGGDL--MYHIQSCHKFDLSRATFYAAEIILGLQFLHSKGIVY 502
F ++ +E L+ MEY GG + +YH+ + F E + GL +LH +G ++
Sbjct: 321 FDSYLRREKLWIAMEYCGGGSMQDIYHVTG--PLTEPQIAFVCRETLKGLHYLHRRGKMH 148
Query: 503 RXXXXXXXXXXXXGHIKIADFGMCKENMLGDAKT-----NTFCGTP 543
R G +K+ADF N + + N F G P
Sbjct: 147 RDIKGANILLTEEGDVKLADFWRVSSNHSHNVQKKVFHWNAFIGWP 10
>12672
Length = 773
Score = 42.0 bits (97), Expect = 8e-04, Method: Compositional matrix adjust.
Identities = 32/114 (28%), Positives = 48/114 (42%), Gaps = 4/114 (3%)
Frame = +3
Query: 491 GLQFLHSKGIVYRXXXXXXXXXXXXGHIKIADFGMCKENMLGDAKT----NTFCGTPDYI 546
G+Q+L+ G V+R K+ DF G+ KT + GT Y+
Sbjct: 27 GIQYLNDNGHVHRDIKTANILLDSEYTAKVGDFATVVSAPSGEGKTVQNASVVIGTAAYL 206
Query: 547 APEILLGQKYNHSVDWWSFGVLLYEMLIGQSPFHGQDEEELFHSIRMDNPFYPR 600
APE + + +D +SFGV+L E++ G EE S M+N P
Sbjct: 207 APE-AIHFDVSTKLDSYSFGVVLLEVITGLVAQDYSREERTLSSHIMENVEEPE 365
>27274
Length = 396
Score = 41.2 bits (95), Expect = 0.001, Method: Composition-based stats.
Identities = 16/31 (51%), Positives = 23/31 (74%)
Frame = -1
Query: 549 EILLGQKYNHSVDWWSFGVLLYEMLIGQSPF 579
E+L GQ++ +VD WS G+LL+E+L G PF
Sbjct: 375 ELLRGQQHGPTVDMWSLGILLHELLSGHVPF 283
>18401
Length = 463
Score = 40.8 bits (94), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 17/50 (34%), Positives = 28/50 (56%)
Frame = -3
Query: 537 NTFCGTPDYIAPEILLGQKYNHSVDWWSFGVLLYEMLIGQSPFHGQDEEE 586
+T T Y APE++L ++H D WS G +++E+ G + F D +E
Sbjct: 458 STIVSTRHYRAPEVILELGWSHPCDVWSVGCIMFELYTGYTLFQTHDNKE 309
>17300
Length = 480
Score = 40.0 bits (92), Expect = 0.003, Method: Composition-based stats.
Identities = 23/78 (29%), Positives = 42/78 (53%), Gaps = 5/78 (6%)
Frame = +1
Query: 519 KIADFGMCKE---NMLGDAKTNTFCGTP-DYIAPEILLGQKYNHSVDWWSFGVLLYE-ML 573
K+ADFG+ +E + A T P + APE + +K+ + D WSFGV+++E M
Sbjct: 94 KVADFGLSREIESDTTEGAYTTKGGKIPVRWTAPEAIAYRKFTSASDVWSFGVVMWEVMS 273
Query: 574 IGQSPFHGQDEEELFHSI 591
G+ P+ +++ ++
Sbjct: 274 YGERPYWNWSNQDVIKAV 327
>17516
Length = 453
Score = 39.7 bits (91), Expect = 0.005, Method: Composition-based stats.
Identities = 17/40 (42%), Positives = 27/40 (67%), Gaps = 1/40 (2%)
Frame = -3
Query: 538 TFCGTPDYIAPEILLGQ-KYNHSVDWWSFGVLLYEMLIGQ 576
T GTP Y+APE+LL + +Y+ D +S ++L+E+ GQ
Sbjct: 442 TLAGTPVYMAPEVLLQKGQYDMKADVYSLAIILWELWYGQ 323
>07291
Length = 833
Score = 39.3 bits (90), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 24/113 (21%), Positives = 50/113 (44%), Gaps = 4/113 (3%)
Frame = +1
Query: 484 YAAEIILGLQFLHSKGIVYRXXXXXXXXXXXXGHIKIADFGMCKENMLGDAKTNTFCGTP 543
+ +I G+ +L +V+R G ++++D+G+ T
Sbjct: 64 FGRQIADGMAYLQEVKVVHRNLAARNCIVTEDGRLQLSDYGVTGSLFPQSYYTADDSPAR 243
Query: 544 D---YIAPEILLGQKYNHSVDWWSFGVLLYEMLI-GQSPFHGQDEEELFHSIR 592
D ++APE + ++ D W+FGV+L+E+L G +P+ + L ++
Sbjct: 244 DLVKWMAPETIDNFHFSSKSDVWAFGVVLWELLTRGITPYPDVENSSLLPYLK 402
>33586
Length = 551
Score = 39.3 bits (90), Expect = 0.006, Method: Composition-based stats.
Identities = 17/49 (34%), Positives = 26/49 (53%)
Frame = +2
Query: 440 FLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEI 488
F+ H+ FQT+ L+ ++E+L GGDL + F FY AE+
Sbjct: 404 FIVHLHYAFQTEGKLYLILEFLRGGDLFTRLSKEVMFTEEDVKFYLAEL 550
>17637
Length = 447
Score = 38.5 bits (88), Expect = 0.010, Method: Compositional matrix adjust.
Identities = 27/91 (29%), Positives = 44/91 (48%), Gaps = 11/91 (12%)
Frame = +1
Query: 518 IKIADFGMCKE------NMLGDAKTNTFCGTPDYIAPEILLGQKYNHSVDWWSFGVLLYE 571
+K+ D + ++ N LGD + +++ E L YN D WSFGVL++E
Sbjct: 28 VKLTDSALSRDLFSGDYNCLGDGEYRPI----KWLSLEALQKSHYNEGSDVWSFGVLMWE 195
Query: 572 M-LIGQSPFHGQDEEELFHSI----RMDNPF 597
M +G+ P+ D E+ H + R+ PF
Sbjct: 196 MCTLGKLPYAEIDPYEMEHYLKDGYRLAQPF 288
>13305
Length = 549
Score = 38.1 bits (87), Expect = 0.012, Method: Composition-based stats.
Identities = 17/45 (37%), Positives = 27/45 (60%), Gaps = 1/45 (2%)
Frame = +2
Query: 545 YIAPEILLGQKYNHSVDWWSFGVLLYEML-IGQSPFHGQDEEELF 588
++A E L Y D WSFGV+L+E+ +G +P+ D ++LF
Sbjct: 23 WMAVESLFNNTYTTQSDVWSFGVVLWEIFTLGGTPYSSTDTQQLF 157
>30743
Length = 569
Score = 37.7 bits (86), Expect = 0.017, Method: Compositional matrix adjust.
Identities = 16/38 (42%), Positives = 23/38 (60%)
Frame = +2
Query: 167 FPQPTFCSVCHEFVWGLNKQGYQCRQCNAAIHKKCIDK 204
F +P C VC + + G+ QGY C+ A+HK+CI K
Sbjct: 347 FEKPKECDVCGKLLRGIFFQGYLCQDNQMAVHKECIGK 460
>20640
Length = 1492
Score = 37.4 bits (85), Expect = 0.019, Method: Compositional matrix adjust.
Identities = 23/78 (29%), Positives = 40/78 (51%), Gaps = 3/78 (3%)
Frame = +1
Query: 518 IKIADFGMCKENMLGDA-KTNTFCGTPDYIAP-EILLGQKYNHSVDWWSFGVLLYEML-I 574
+KI+DFG+ + D + + P P E +L K++ D WSFGV+L+E+
Sbjct: 61 VKISDFGLARSVHSVDYYRGSEHDAIPIRWMPLEAILYNKFSTQSDVWSFGVVLWEIFAF 240
Query: 575 GQSPFHGQDEEELFHSIR 592
P++G EE+ ++
Sbjct: 241 ALQPYYGLTHEEVVRFVK 294
>36002
Length = 253
Score = 37.0 bits (84), Expect = 0.026, Method: Compositional matrix adjust.
Identities = 22/53 (41%), Positives = 30/53 (56%), Gaps = 4/53 (7%)
Frame = +1
Query: 584 EEELFHSIRMDNPFYP--RW--LEKEAKDLLVKLFVREPEKRLGVRGDIRQHP 632
+E LF+ I+ N F+P W + AKDL+ L VREP KR D+ +HP
Sbjct: 49 QELLFNRIQDGNYFFPSMEWSAISSSAKDLIRHLLVREPRKRYSA-ADVLKHP 204
>30339
Length = 384
Score = 34.7 bits (78), Expect = 0.13, Method: Composition-based stats.
Identities = 16/27 (59%), Positives = 19/27 (70%)
Frame = -2
Query: 374 KLKIEDFILHKMLGKGSFGKVFLAEFK 400
+ + DF K+LGKGSFGKV LAE K
Sbjct: 86 RFHLHDFNFIKVLGKGSFGKVMLAERK 6
>17975
Length = 449
Score = 34.3 bits (77), Expect = 0.17, Method: Composition-based stats.
Identities = 23/99 (23%), Positives = 45/99 (45%), Gaps = 2/99 (2%)
Frame = +3
Query: 428 EKRVLSLAWEHPFLTHMFCTFQTKENLFFVMEYLNGGDLM-YHIQSCHKFDLSRATFYAA 486
E R + L +HP + ++ T+ L+ ++E +GGD+ Y ++ + A Y
Sbjct: 114 EVRCMKLV-QHPNVVRLYEVIDTQTKLYLILELGDGGDMYDYIMRHSGGLEEKLAKRYFR 290
Query: 487 EIILGLQFLHSKGIVYRXXX-XXXXXXXXXGHIKIADFG 524
+I+ + + H +V+R G +K+ DFG
Sbjct: 291 QIVEAISYCHKLHVVHRDLKPENVVFFEKPGLVKLTDFG 407
>18996
Length = 491
Score = 32.3 bits (72), Expect = 0.60, Method: Compositional matrix adjust.
Identities = 24/82 (29%), Positives = 40/82 (48%), Gaps = 7/82 (8%)
Frame = +2
Query: 518 IKIADFGMCK-ENMLGDAKTNTFCGTP-DYIAPEILLGQKYNHSVDWWSFGVLLYEM--- 572
+KI+DFG+ + N G + P + +PE + K++ D WS+GV L+EM
Sbjct: 50 VKISDFGLAQFANADGYYYGISQRDIPIKWYSPEAIETCKFSSYSDVWSYGVTLFEMFSR 229
Query: 573 --LIGQSPFHGQDEEELFHSIR 592
+ P H +EE + +R
Sbjct: 230 GEIPNLLPGHDLTQEEFLNRLR 295
>23319
Length = 2235
Score = 31.6 bits (70), Expect = 1.1, Method: Compositional matrix adjust.
Identities = 27/120 (22%), Positives = 46/120 (38%), Gaps = 30/120 (25%)
Frame = +3
Query: 548 PEILLGQKYNHSVDWWSFGVLLYEML-IGQSPFHGQDEEELFHSI--RMDNPFYPRW--- 601
P++ + Y+ S+D WS G + E+ G+ F G D+++ I + P +W
Sbjct: 3 PDVYXAKMYSTSIDMWSAGCIFAELANAGRPLFPGNDDDDQLKRIFKLLGTPTEDQWPGM 182
Query: 602 ------------------------LEKEAKDLLVKLFVREPEKRLGVRGDIRQHPLFREI 637
L + +DLL L V P R+ + QHP F ++
Sbjct: 183 TQLPNYRMFPMYHVTTTWQQVVPKLNSKGRDLLQCLLVCCPSDRMSA-DEALQHPYFADL 359
>26009
Length = 886
Score = 31.6 bits (70), Expect = 1.1, Method: Compositional matrix adjust.
Identities = 27/99 (27%), Positives = 43/99 (43%), Gaps = 6/99 (6%)
Frame = +2
Query: 378 EDFILHKMLGKGSFGKVFLAEFKKTNQFFAIKAXXXXXXXXXXXXECTMVE--KRVLSLA 435
E + + K LG+G++GKV LA + T A+K CT + +R L+
Sbjct: 416 EHYDVCKELGRGTYGKVVLARCRHTGTQVALK---------LLPKSCTKLREFQREFQLS 568
Query: 436 W---EHPFLTHMF-CTFQTKENLFFVMEYLNGGDLMYHI 470
+ H + + FQT+ + F E+ GDL I
Sbjct: 569 YFLSPHANIIDTYNVAFQTRSSYVFAQEHAVLGDLFDAI 685
>26052
Length = 562
Score = 31.2 bits (69), Expect = 1.5, Method: Composition-based stats.
Identities = 13/30 (43%), Positives = 19/30 (63%)
Frame = -1
Query: 380 FILHKMLGKGSFGKVFLAEFKKTNQFFAIK 409
++ K+LG GSFGKV + K T + A+K
Sbjct: 385 YLFXKLLGVGSFGKVMALQHKDTGETLAVK 296
>03294
Length = 1684
Score = 30.0 bits (66), Expect = 3.8, Method: Compositional matrix adjust.
Identities = 15/37 (40%), Positives = 20/37 (54%), Gaps = 1/37 (2%)
Frame = -1
Query: 558 HSVDWWSFGVLLYEMLIGQSPFHGQDE-EELFHSIRM 593
H VD WS G + +MLI F G E ++LF R+
Sbjct: 1678 HPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRI 1568
>13477
Length = 568
Score = 29.3 bits (64), Expect = 6.1, Method: Composition-based stats.
Identities = 12/31 (38%), Positives = 19/31 (61%)
Frame = +3
Query: 455 FFVMEYLNGGDLMYHIQSCHKFDLSRATFYA 485
F V ++L +++ H+QS HKF S T +A
Sbjct: 297 FLVTKWLCTSNILIHLQSAHKFYFSMYTLHA 389
>12041
Length = 575
Score = 28.9 bits (63), Expect = 7.0, Method: Composition-based stats.
Identities = 13/32 (40%), Positives = 18/32 (56%), Gaps = 1/32 (3%)
Frame = -1
Query: 245 CEHCG-TLLWGLARQGLKCDACGMNVHHRCQT 275
C C T+ W +G+ CD CG+ H RCQ+
Sbjct: 278 CGTCDITISW--TEKGVVCDTCGLWFHARCQS 189
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000380363 | hsapiens_gene_ensembl | Protein kinase
C theta type (EC 2.7.11.13) (nPKC-theta).
[Source:Uniprot/SWISSPROT;Acc:Q04759]
(706 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
18484 192 4e-57
30755 193 2e-49
18663 145 7e-35
03240 138 6e-33
00486 128 7e-30
27405 102 5e-22
17722 101 1e-21
26156 80 6e-21
12721 96 4e-20
15910 96 4e-20
26560 95 1e-19
31885 91 2e-18
14420 86 6e-17
18921 84 1e-16
25445 83 3e-16
06405 82 5e-16
00300 82 5e-16
09606 79 8e-15
01060 77 2e-14
21433 62 6e-14
01707 74 2e-13
01392 74 3e-13
13212 72 9e-13
14126 70 2e-12
25019 70 2e-12
11353 67 2e-11
21079 65 7e-11
38560 64 3e-10
13592 63 3e-10
22804 63 4e-10
21808 62 6e-10
13066 62 1e-09
19361 60 2e-09
01756 59 6e-09
17591 52 6e-09
17932 43 9e-09
32957 58 1e-08
04852 58 2e-08
07940 58 2e-08
19094 57 3e-08
01718 57 3e-08
20152 56 6e-08
35187 55 7e-08
29581 55 9e-08
04591 55 1e-07
00392 52 8e-07
02638 51 1e-06
12786 50 2e-06
01966 50 2e-06
11185 50 4e-06
29590 49 8e-06
14116 49 8e-06
27546 48 1e-05
09007 48 1e-05
08294 42 4e-05
26711 46 6e-05
28638 44 2e-04
04138 44 3e-04
19761 44 3e-04
37602 43 4e-04
12672 42 8e-04
27274 41 0.001
18401 41 0.002
17300 40 0.003
17516 40 0.005
07291 39 0.006
33586 39 0.006
17637 39 0.010
13305 38 0.012
30743 38 0.017
20640 37 0.019
36002 37 0.026
30339 35 0.13
17975 34 0.17
18996 32 0.60
23319 32 1.1
26009 32 1.1
26052 31 1.5
03294 30 3.8
13477 29 6.1
12041 29 7.0
>18484
Length = 635
Score = 192 bits (488), Expect(2) = 4e-57, Method: Compositional matrix adjust.
Identities = 94/159 (59%), Positives = 109/159 (68%)
Frame = +1
Query: 465 DLMYHIQSCHKFDLSRATFYAAEIILGLQFLHSKGIVYRXXXXXXXXXXXXGHIKIADFG 524
DLMY IQ KF A FYAAEI +GL FLH +GI+YR GHIKIADFG
Sbjct: 1 DLMYRIQQEGKFKEPVAAFYAAEIAVGLFFLHDQGIIYRDLKLDNVMLDSEGHIKIADFG 180
Query: 525 MCKENMLGDAKTNTFCGTPDYIAPEILLGQKYNHSVDWWSFGVLLYEMLIGQSPFHGQDE 584
MCKE M GDA T TFCGTPDYIAPEI+L Q Y+ SVDWW++GVLL+EML GQ PF G+DE
Sbjct: 181 MCKEGMTGDATTRTFCGTPDYIAPEIVLYQPYSKSVDWWAYGVLLFEMLAGQPPFDGEDE 360
Query: 585 EELFHSIRMDNPFYPRWLEKEAKDLLVKLFVREPEKRLG 623
+ELF SI N YP+ + +EA L L ++ P KRLG
Sbjct: 361 DELFSSITDHNVSYPKAMSREAVSLCKGLLMKNPTKRLG 477
Score = 48.1 bits (113), Expect(2) = 4e-57, Method: Composition-based stats.
Identities = 18/42 (42%), Positives = 26/42 (61%)
Frame = +2
Query: 627 DIRQHPLFREINWEELERKEIDPPFRPKVKSPFDCSNFDKEF 668
DIR H FR I W++++ E+ PP++PK+ NFDK F
Sbjct: 500 DIRDHAFFRRIVWDKIKSMEVQPPYKPKITDRRKAENFDKSF 625
>30755
Length = 1137
Score = 193 bits (490), Expect = 2e-49, Method: Compositional matrix adjust.
Identities = 98/234 (41%), Positives = 137/234 (58%), Gaps = 6/234 (2%)
Frame = +2
Query: 469 HIQSCHKFDLSRATFYAAEIILGLQFLHSKGIVYRXXXXXXXXXXXXGHIKIADFGMCKE 528
H+ F R FY AEII L +LHS+GI+YR GHIK+ADFG+CKE
Sbjct: 2 HLSHERIFTEERTRFYGAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCKE 181
Query: 529 NMLGDAKTNTFCGTPDYIAPEILLGQKYNHSVDWWSFGVLLYEMLIGQSPFHGQDEEELF 588
++ T TFCGTP+Y+APE+L Y +VDWW GV++YEM+ G+ PF+ +D + LF
Sbjct: 182 DITYGRTTKTFCGTPEYLAPEVLDDNDYGRAVDWWGTGVVMYEMICGRLPFYNRDHDVLF 361
Query: 589 HSIRMDNPFYPRWLEKEAKDLLVKLFVREPEKRLGVRGD----IRQHPLFREINWEELER 644
I +++ +PR + EAK LL L ++P RLG D I+ HP F INW +L +
Sbjct: 362 TLILVEDVKFPRNITDEAKSLLSGLLAKDPRNRLGGGQDDVKEIQAHPFFASINWTDLVQ 541
Query: 645 KEIDPPFRPKVKSPFDCSNFDKEFLNEKPRLSFADRA--LINSMDQNMFRNFSF 696
K+I PPF+P+V S D FD+EF E L+ D L + ++ +F FS+
Sbjct: 542 KKITPPFKPQVTSDTDTRYFDEEFTGESVELTPPDPTGPLXSIAEEPLFPQFSY 703
>18663
Length = 600
Score = 145 bits (365), Expect = 7e-35, Method: Compositional matrix adjust.
Identities = 79/182 (43%), Positives = 105/182 (57%), Gaps = 14/182 (7%)
Frame = +2
Query: 537 NTFCGTPDYIAPEILLGQKYNHSVDWWSFGVLLYEMLIGQSPF---------HGQDEEEL 587
+TFCGTP+YIAPEIL G+ Y SVDWW+ GVLLYEML G+SPF E+ L
Sbjct: 2 STFCGTPNYIAPEILRGEDYGFSVDWWALGVLLYEMLAGRSPFDIAGASENPDQNTEDYL 181
Query: 588 FHSIRMDNPFYPRWLEKEAKDLLVKLFVREPEKRLGVRG-----DIRQHPLFREINWEEL 642
F I PR L +A +L + P RLG DI HP F+ I+WE L
Sbjct: 182 FQVILEKTIRIPRSLSVKAASVLKGFLNKNPADRLGCHRESAFMDIVNHPFFKVIDWEML 361
Query: 643 ERKEIDPPFRPKVKSPFDCSNFDKEFLNEKPRLSFADRALINSMDQNMFRNFSFMNPGME 702
ERK++ PPF+P++ S D +NF EF E +L+ D +I+S+DQ+ F F ++NP +
Sbjct: 362 ERKQVSPPFKPRLDSDRDLANFPIEFTGEPVQLTPDDDHVIDSIDQSEFEGFEYVNPLLM 541
Query: 703 RL 704
L
Sbjct: 542 SL 547
>03240
Length = 1683
Score = 138 bits (348), Expect = 6e-33, Method: Compositional matrix adjust.
Identities = 98/334 (29%), Positives = 154/334 (46%), Gaps = 52/334 (15%)
Frame = -3
Query: 384 KMLGKGSFGKVFLAEFKKTNQFFAIKAXXXXXXXXXXXXECTMVEKRVLSLAWEHPFLTH 443
K LG G+FG+V L T +A+K E+ +L+ A ++ ++
Sbjct: 1273 KTLGVGAFGEVSLCRKNDTGMLYAMKTLRKSDVLKRNQVAHVKAERDILAEA-DNEWVVK 1097
Query: 444 MFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEIILGLQFLHSKGIVYR 503
++ +FQ L+FVM+Y+ GGDLM + D A FY AE++ ++ +H G ++R
Sbjct: 1096 LYYSFQDHNYLYFVMDYVPGGDLMGLLIRMEILDEPLARFYVAELVQAIESVHRMGFIHR 917
Query: 504 XXXXXXXXXXXXGHIKIADFGMC--------------------KENMLGDAKTNTFC--- 540
GHIK+ DFG+C +++M + + C
Sbjct: 916 DIKPDNILIDRNGHIKLTDFGLCTGFRWTHNSKYYQRDGTHARQDSMEVKCQLDEQCQCE 737
Query: 541 ---------------------GTPDYIAPEIL--LGQKYNHSVDWWSFGVLLYEMLIGQS 577
GTP+YIAPE+L LG Y DWWS GV+L+EML+G
Sbjct: 736 ILKPLERRRKREQRCLAHSLVGTPNYIAPEVLSRLG-GYTSVCDWWSVGVILFEMLVGHP 560
Query: 578 PFHGQDEEELFHSIR--MDNPFYPRW--LEKEAKDLLVKLFVREPEKRLGVR--GDIRQH 631
PF+ E + + D PR L + AKDL+++L + RLG+ G+I+ H
Sbjct: 559 PFYANTPAETQYKVINWKDMLKIPRESNLSQPAKDLILRLCC-GSDDRLGLNGAGEIKTH 383
Query: 632 PLFREINWEELERKEIDPPFRPKVKSPFDCSNFD 665
F +N+E L +++ PP+ P ++ D SNFD
Sbjct: 382 MFFAGVNFETLRKQQ--PPYVPNIRYATDTSNFD 287
>00486
Length = 797
Score = 128 bits (322), Expect = 7e-30, Method: Compositional matrix adjust.
Identities = 66/170 (38%), Positives = 96/170 (56%), Gaps = 4/170 (2%)
Frame = -2
Query: 536 TNTFCGTPDYIAPEILLGQKYNHSVDWWSFGVLLYEMLIGQSPFHGQDEEELFHSIRMDN 595
T+TFCGT +Y+APEIL + +VDWWS G L+Y+ML G PF ++ ++ I
Sbjct: 787 THTFCGTIEYMAPEILTRTGHGKAVDWWSLGALMYDMLTGSPPFTAENRKKTIDKILKGK 608
Query: 596 PFYPRWLEKEAKDLLVKLFVREPEKRLGV----RGDIRQHPLFREINWEELERKEIDPPF 651
P +L EA+ L+ KL + P +RLG G I+ H FR NW L + +PPF
Sbjct: 607 LNLPPYLTNEARGLIKKLLRKNPAERLGGGHDDSGPIKDHQFFRNTNWALLALRRAEPPF 428
Query: 652 RPKVKSPFDCSNFDKEFLNEKPRLSFADRALINSMDQNMFRNFSFMNPGM 701
RP V S D S FD +F + P S D L +S++Q +F+ F+++ P +
Sbjct: 427 RPNVTSDEDTSQFDTKFTRQTPVDSPDDTILSDSINQ-VFKGFTYIAPSV 281
>27405
Length = 532
Score = 102 bits (254), Expect = 5e-22, Method: Compositional matrix adjust.
Identities = 59/178 (33%), Positives = 90/178 (50%), Gaps = 4/178 (2%)
Frame = -3
Query: 390 SFGKVFLAEFKKTNQFFAIKAXXXXXXXXXXXXECTMVEKRVLSLAWE---HPFLTHMFC 446
FG+V+ T + +A+K + E+ +LSL PF+ M
Sbjct: 530 GFGEVYGCRKADTGKMYAMKCLDKKRIKMKGGETLALNERIMLSLVSTGEGSPFIVCMTY 351
Query: 447 TFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEIILGLQFLHSKGIVYRXXX 506
FQT E L F+++ +NGGDL YH+ F FYAAE++LGL+ +HS+ +VYR
Sbjct: 350 AFQTPEKLCFILDLMNGGDLHYHLSQHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLK 171
Query: 507 XXXXXXXXXGHIKIADFGMCKENMLGDAKTNTFCGTPDYIAPEILL-GQKYNHSVDWW 563
GH++I+D G+ + K + GT Y+APE+L+ GQ Y+ S DW+
Sbjct: 170 PANILLDENGHVRISDLGLACD--FSKKKPHASVGTHGYMAPEVLMKGQAYDSSADWF 3
>17722
Length = 680
Score = 101 bits (251), Expect = 1e-21, Method: Compositional matrix adjust.
Identities = 54/133 (40%), Positives = 79/133 (59%), Gaps = 5/133 (3%)
Frame = -3
Query: 560 VDWWSFGVLLYEMLIGQSPFHGQDEEELFHSIRMDNPFYPRWLEKEAKDLLVKLFVREPE 619
VDWW GV++YEM+ G+ PF+ +D + LF I + N +PR L +EAK LL L + P+
Sbjct: 678 VDWWGTGVVMYEMMCGRLPFYNRDHDVLFELILLQNVKFPRNLSEEAKTLLSGLLAKNPK 499
Query: 620 KRLGVR----GDIRQHPLFREINWEELERKEIDPPFRPKVKSPFDCSNFDKEFLNEKPRL 675
+RLG +I+ HP F+ INW++L K+I PP++P VKS +D +EF E L
Sbjct: 498 RRLGGSEADVTEIKTHPFFQCINWDDLAAKKITPPWKPDVKSSWDTKYIPEEFAQESLHL 319
Query: 676 SFA-DRALINSMD 687
+ D L +D
Sbjct: 318 TPGHDHPLAERLD 280
>26156
Length = 479
Score = 80.5 bits (197), Expect(2) = 6e-21, Method: Compositional matrix adjust.
Identities = 39/110 (35%), Positives = 61/110 (55%)
Frame = -1
Query: 374 KLKIEDFILHKMLGKGSFGKVFLAEFKKTNQFFAIKAXXXXXXXXXXXXECTMVEKRVLS 433
KL + DF+L +++G+GS+ KV E K+T + +A+K + EK V
Sbjct: 401 KLGLTDFLLLRVIGRGSYAKVLQVEHKRTKRIYAMKVIKKELVNDDEDIDWVQTEKHVFE 222
Query: 434 LAWEHPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATF 483
A +PFL + FQ++ LFFV+E++NGGDLM+H+Q + A F
Sbjct: 221 TATNYPFLVGLHSCFQSESRLFFVIEFVNGGDLMFHMQRQRRLPEEHARF 72
Score = 39.3 bits (90), Expect(2) = 6e-21, Method: Composition-based stats.
Identities = 16/22 (72%), Positives = 18/22 (81%)
Frame = -3
Query: 482 TFYAAEIILGLQFLHSKGIVYR 503
TFY+AEI L L FLH +GIVYR
Sbjct: 78 TFYSAEICLALNFLHKRGIVYR 13
>12721
Length = 821
Score = 96.3 bits (238), Expect = 4e-20, Method: Compositional matrix adjust.
Identities = 71/276 (25%), Positives = 127/276 (46%), Gaps = 13/276 (4%)
Frame = +1
Query: 359 LPEPE-LNKE--RPSLQIKLK-------IEDFILHKMLGKGSFGKVFLAEFKKTNQFFAI 408
+PEP+ L+ E R +LQ+ + ++DF+ +G+GS G V +A + Q A+
Sbjct: 10 MPEPQRLSHEQFRAALQMVVTPGDPRTFLDDFM---KIGEGSTGIVCIATSRDGRQM-AV 177
Query: 409 KAXXXXXXXXXXXXECTMVEKRVLSLAWEHPFLTHMFCTFQTKENLFFVMEYLNGGDLMY 468
K + + V+ + HP + M+ ++ + L+ VME++ GG L
Sbjct: 178 KKMDLRKQQRRE----LLFNEVVVMRDYHHPNIVEMYNSYLVNDELWVVMEFMEGGAL-T 342
Query: 469 HIQSCHKFDLSRATFYAAEIILGLQFLHSKGIVYRXXXXXXXXXXXXGHIKIADFGMCKE 528
I + ++ D + + L FLH+ G+++R G +K+ DFG C +
Sbjct: 343 DIVTNNRMDEVQIATVCRACLKALAFLHANGVIHRDIKSDSILLSHDGKVKLXDFGFCAQ 522
Query: 529 NMLGDAKTNTFCGTPDYIAPEILLGQKYNHSVDWWSFGVLLYEMLIGQSPFHGQDEEELF 588
K + GTP ++APE++ Y VD WS G+++ EM+ + PF + +
Sbjct: 523 VTQDLQKRKSLVGTPYWMAPEVISRLPYGPEVDIWSLGIMVMEMIDAEPPFFNEPPLQAM 702
Query: 589 HSIRMDNPFYPRWLEKEAKDL---LVKLFVREPEKR 621
IR P R K + L + ++ VR+P +R
Sbjct: 703 RRIRDMPPPKLRNTHKISPRLQGFIDRMLVRDPHQR 810
>15910
Length = 1361
Score = 96.3 bits (238), Expect = 4e-20, Method: Compositional matrix adjust.
Identities = 55/161 (34%), Positives = 90/161 (55%), Gaps = 8/161 (4%)
Frame = +2
Query: 477 DLSRATFYAAEIILGLQFLHSKGIVYRXXXXXXXX---XXXXGHIKIADFGMCKENMLGD 533
D +RA ++I+ G+Q++H+ G+V+R +K+ADFG+ + + +
Sbjct: 467 DAARAI---SDILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLADFGLSR-IIEPE 634
Query: 534 AKTNTFCGTPDYIAPEILLGQKYNHSVDWWSFGVLLYEMLIGQSPFHGQDEEELFHSI-- 591
+ +T CGTP Y APE+L G KY SVD WS GV+ Y +L G PF ++E E++ I
Sbjct: 635 VQMSTVCGTPGYCAPEVLKGDKYTPSVDMWSVGVIAYILLCGYEPFFAENEFEMYRKIIK 814
Query: 592 ---RMDNPFYPRWLEKEAKDLLVKLFVREPEKRLGVRGDIR 629
+ D ++ + + AKD++ KL V +P+KRL +R
Sbjct: 815 GEYKFDEEYWSE-ISENAKDVVRKLLVIDPKKRLTATEALR 934
>26560
Length = 398
Score = 94.7 bits (234), Expect = 1e-19, Method: Composition-based stats.
Identities = 46/121 (38%), Positives = 70/121 (57%), Gaps = 1/121 (0%)
Frame = -1
Query: 465 DLMYHIQSCHKFDLSRATFYAAEIILGLQFLHSKGIVYRXXXXXXXXXXXXGHIKIADFG 524
DL YH+ F FYAAE++LGL+ +HS+ +VYR GH++I+D G
Sbjct: 398 DLHYHLSQHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLG 219
Query: 525 MCKENMLGDAKTNTFCGTPDYIAPEILL-GQKYNHSVDWWSFGVLLYEMLIGQSPFHGQD 583
+ + + + GT Y+APE+L+ GQ Y+ S DW+SFG +LY++L G SPF +
Sbjct: 218 LACD--FSKKRPHASVGTHGYMAPEVLMKGQSYDSSADWFSFGCMLYKLLKGHSPFRQHN 45
Query: 584 E 584
+
Sbjct: 44 Q 42
>31885
Length = 529
Score = 90.9 bits (224), Expect = 2e-18, Method: Compositional matrix adjust.
Identities = 51/148 (34%), Positives = 78/148 (52%), Gaps = 5/148 (3%)
Frame = -2
Query: 437 EHPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEIILGLQFLH 496
+HPFL +++ FQ +E+LF V++ GGDL YH+Q F FY ++ L L +L
Sbjct: 498 DHPFLVNLWYAFQDEEDLFMVVDLFLGGDLRYHMQQEVSFREDCVKFYLCQLALVLDYLR 319
Query: 497 SKGIVYRXXXXXXXXXXXXGHIKIADFGMCKENMLGDAKTNTFCGTPDYIAPEIL---LG 553
S+ IV+R GH + DF + + + D + GT Y+APE+ +
Sbjct: 318 SQKIVHRDIKPDNILLDEQGHCHVTDFNIATQ-LEDDELATSTSGTRPYMAPEVYGVAIN 142
Query: 554 QK--YNHSVDWWSFGVLLYEMLIGQSPF 579
++ Y VDWWS GV L+E+L + PF
Sbjct: 141 ERRGYGFPVDWWSLGVSLFELLKKRRPF 58
>14420
Length = 528
Score = 85.5 bits (210), Expect = 6e-17, Method: Compositional matrix adjust.
Identities = 43/148 (29%), Positives = 78/148 (52%), Gaps = 1/148 (0%)
Frame = +2
Query: 437 EHPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHI-QSCHKFDLSRATFYAAEIILGLQFL 495
++P + + ++ E L+ VME+L GG L + ++C D + E + L+FL
Sbjct: 74 QNPNIVNYLDSYLVGEELWVVMEFLAGGSLTDVVTETC--MDEGQIAAVCRECLQALEFL 247
Query: 496 HSKGIVYRXXXXXXXXXXXXGHIKIADFGMCKENMLGDAKTNTFCGTPDYIAPEILLGQK 555
H +++R G +K+ DFG C + +K +T GTP ++APE++ ++
Sbjct: 248 HENQVIHRDIKSDNILLGMDGSVKLTDFGFCAQLSPEQSKRSTMVGTPYWMAPEVVTRKQ 427
Query: 556 YNHSVDWWSFGVLLYEMLIGQSPFHGQD 583
Y +VD WS GV+ EM+ G+ P+ ++
Sbjct: 428 YGPTVDIWSLGVMCIEMIEGEPPYLNEN 511
>18921
Length = 697
Score = 84.3 bits (207), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 55/198 (27%), Positives = 95/198 (47%), Gaps = 4/198 (2%)
Frame = +2
Query: 386 LGKGSFGKVFLAEFKKTNQFFAIKAXXXXXXXXXXXXECTMVEKRVLSLAWEHPFLTHMF 445
LG+GS+G VF + K+T Q AIK E +++++ + ++ +
Sbjct: 53 LGEGSYGSVFKSLHKETGQVLAIKQVPVDTDLQEIIKEISIMQQ------CDSKYIVKYY 214
Query: 446 CTFQTKENLFFVMEYLNGG---DLM-YHIQSCHKFDLSRATFYAAEIILGLQFLHSKGIV 501
++ +L+ VMEY G D+M ++ + +++ +Y + GL +LHS+ +
Sbjct: 215 GSYFKNTDLWIVMEYCGAGSVSDIMRLRNKTLVEREIATILYYTLK---GLXYLHSRRKI 385
Query: 502 YRXXXXXXXXXXXXGHIKIADFGMCKENMLGDAKTNTFCGTPDYIAPEILLGQKYNHSVD 561
+R GH K+ADFG+ + AK NT GTP ++APE++ Y+ D
Sbjct: 386 HRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTPYWMAPEVIQEIGYDCVAD 565
Query: 562 WWSFGVLLYEMLIGQSPF 579
WS G+ EM G+ P
Sbjct: 566 IWSLGITALEMAEGKPPV 619
>25445
Length = 460
Score = 83.2 bits (204), Expect = 3e-16, Method: Composition-based stats.
Identities = 32/54 (59%), Positives = 41/54 (75%)
Frame = -1
Query: 232 HRFKVYNYKSPTFCEHCGTLLWGLARQGLKCDACGMNVHHRCQTKVANLCGINQ 285
H+FK + Y SPTFC+HCG+LL+GL QGLKCD+C MN H RC+ V LCG++
Sbjct: 397 HKFKAHTYGSPTFCDHCGSLLYGLIHQGLKCDSCDMNCHKRCEKHVPRLCGMDH 236
Score = 45.1 bits (105), Expect = 1e-04, Method: Composition-based stats.
Identities = 19/50 (38%), Positives = 26/50 (52%)
Frame = -1
Query: 160 HEFTATFFPQPTFCSVCHEFVWGLNKQGYQCRQCNAAIHKKCIDKVIAKC 209
H+F A + PTFC C ++GL QG +C C+ HK+C V C
Sbjct: 397 HKFKAHTYGSPTFCDHCGSLLYGLIHQGLKCDSCDMNCHKRCEKHVPRLC 248
>06405
Length = 1965
Score = 82.4 bits (202), Expect = 5e-16, Method: Compositional matrix adjust.
Identities = 54/228 (23%), Positives = 104/228 (45%), Gaps = 10/228 (4%)
Frame = +1
Query: 379 DFILHKMLGKGSFGKVFLAEFKKTNQFFAIKAXXXXXXXXXXXXECTMVEKRVLSLAWEH 438
+ + LG G +G V+ A +K+ N+ A+K E + K + +H
Sbjct: 262 EIAMKHRLGGGQYGDVYEAMWKRYNKIVAVKTLKEDTMALNDFLEEAAIMKEM-----KH 426
Query: 439 PFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFD--LSRATFYAAEIILGLQFLH 496
P L + + + V E++ G+L+ +++S + + + + A +I G+ +L
Sbjct: 427 PNLVQLLGVCTREPPFYIVTEFMPHGNLLDYLRSSTREENGPTALMYMATQIASGMAYLE 606
Query: 497 SKGIVYRXXXXXXXXXXXXGHIKIADFGMCKENMLGDAKTNTFCGTP---DYIAPEILLG 553
+K ++R +K+ADFG+ + ++ D G + APE L
Sbjct: 607 TKNFIHRDLAARNCLVADSNMVKVADFGLAR--LMKDDTYTAHIGAKFPIKWTAPEGLAF 780
Query: 554 QKYNHSVDWWSFGVLLYEMLI-GQSPFHGQDEEELFHSI----RMDNP 596
+++ D W+FGVLL+E+ G SP+ G + E++H + RM+ P
Sbjct: 781 NRFSTRSDIWAFGVLLWELATYGMSPYPGVELTEVYHLLERGYRMERP 924
>00300
Length = 2318
Score = 82.4 bits (202), Expect = 5e-16, Method: Compositional matrix adjust.
Identities = 63/246 (25%), Positives = 101/246 (41%), Gaps = 10/246 (4%)
Frame = -1
Query: 386 LGKGSFGKVFLAEFKKTNQFFAIKAXXXXXXXXXXXXECTMVEKRVLSLAWEHPFLTHMF 445
+G+G FGKV+ A T + A+K E M ++ + +H L +
Sbjct: 1634 IGEGQFGKVYTAVNMSTGELMALKEMKFQPNDLQQLRE--MCDEIKIFEGIQHENLVKYY 1461
Query: 446 CTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATF--YAAEIILGLQFLHSKGIVYR 503
K+ + MEY + G I+ K L Y EI+L + LH IV+R
Sbjct: 1460 GVEVHKDEMLMFMEYCDTGT----IEEAAKMGLPEYLIRRYTREIVLAVNHLHENSIVHR 1293
Query: 504 XXXXXXXXXXXXGHIKIADFG---MCKENMLGDAKTNTFCGTPDYIAPEILLGQK---YN 557
GH+K+ DFG K + + + GT Y+APE+ Y
Sbjct: 1292 DIKGANIFLTSNGHVKLGDFGCSVKLKSHTTMPGEFHNLVGTTAYMAPEVFTQNDQGGYG 1113
Query: 558 HSVDWWSFGVLLYEMLIGQSPFHGQDEE-ELFHSIRMDN-PFYPRWLEKEAKDLLVKLFV 615
+ D WS G ++ EM G+ P+H D ++ + + + + P P L E K L +
Sbjct: 1112 RAADIWSLGCVVIEMATGKRPWHDLDNNYQIMYKVGIGHKPAVPDSLSVEGKHFLDLIMC 933
Query: 616 REPEKR 621
+P +R
Sbjct: 932 HDPAQR 915
>09606
Length = 1300
Score = 78.6 bits (192), Expect = 8e-15, Method: Compositional matrix adjust.
Identities = 59/229 (25%), Positives = 96/229 (41%), Gaps = 22/229 (9%)
Frame = -3
Query: 376 KIEDFILHKMLGKGSFGKVFLAEFKKTNQFFAIKAXXXXXXXXXXXXECTMVEKRVLSLA 435
++E+F+L++ LGKG ++ K T F AI E T + ++
Sbjct: 1121 RMENFVLYEELGKGEHSIIYKGRRKGTINFVAIHCIEKCKRP-----EVTNTVRMTHDIS 957
Query: 436 WEHPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEIILGLQFL 495
HP + ++T +L+ V+E GG L + H + + ++ GL ++
Sbjct: 956 --HPNVVQFHEWYETSNHLWLVVELCTGGSLADILAQDHHLPETSIRDFGIHLVTGLHYI 783
Query: 496 HSKGIVYRXXXXXXXXXXXXGHIKIADFGMCK---ENM---------LGD---------- 533
HS GI++ G +K ADFG+ K EN+ GD
Sbjct: 782 HSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQWNIQSAEEM 603
Query: 534 AKTNTFCGTPDYIAPEILLGQKYNHSVDWWSFGVLLYEMLIGQSPFHGQ 582
K G+P Y+APE+ G + + D W+ G + YEM G PF G+
Sbjct: 602 MKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSGHPPFLGE 456
>01060
Length = 1800
Score = 77.4 bits (189), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 64/235 (27%), Positives = 100/235 (42%), Gaps = 4/235 (1%)
Frame = +1
Query: 363 ELNKERPSLQIKLKIEDFILHKMLGKGSFGKVFLAEFKKTNQFFAIKAXXXXXXXXXXXX 422
+LN +R + + + D + +G+G++G V+ + T + A+K
Sbjct: 28 KLNIKRLMMDFETALSDLTDFQKIGEGTYGVVYKCRHRATGRKLAMKKIRLRGSEDGV-- 201
Query: 423 ECTMVEKRVLSLAWEHPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRAT 482
+ + + + H + + E LF V E+L+ MY + L R
Sbjct: 202 PSSAIREIAMLRELRHTNIVCLEDVIMEDERLFLVFEFLSMDLKMYIDKFPEGVVLDRRL 381
Query: 483 F--YAAEIILGLQFLHSKGIVYRXXXXXXXXXXXXGHIKIADFGMCKENMLGDAKTNTFC 540
Y +I+ G+ F H + IV+R G IKIADFGM + L
Sbjct: 382 VKSYVFQIVTGIXFCHQRRIVHRDLKPQNLLINHTGAIKIADFGMARTFALPVRAYTHEV 561
Query: 541 GTPDYIAPEILLG-QKYNHSVDWWSFGVLLYEMLIGQSPFHGQDE-EELFHSIRM 593
T Y APEIL+G KY+ VD WS G + +MLI F G E ++LF R+
Sbjct: 562 VTLWYRAPEILMGASKYSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRI 726
>21433
Length = 590
Score = 62.4 bits (150), Expect(2) = 6e-14, Method: Composition-based stats.
Identities = 33/100 (33%), Positives = 52/100 (52%)
Frame = +2
Query: 480 RATFYAAEIILGLQFLHSKGIVYRXXXXXXXXXXXXGHIKIADFGMCKENMLGDAKTNTF 539
R Y ++ L++ H + +++R G +KIADFG ++ T
Sbjct: 170 RTACYIYQLSSALEYCHYRKVIHRDIKPENLLLGLKGDLKIADFGWSVH--APSSRRTTM 343
Query: 540 CGTPDYIAPEILLGQKYNHSVDWWSFGVLLYEMLIGQSPF 579
CGT DY+ PE++ G+ ++ +VD WS GVL YE L+G P
Sbjct: 344 CGTLDYLPPEMVEGKTHDENVDLWSLGVLCYEFLVGTPPL 463
Score = 33.9 bits (76), Expect(2) = 6e-14, Method: Compositional matrix adjust.
Identities = 14/40 (35%), Positives = 22/40 (55%)
Frame = +3
Query: 438 HPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFD 477
H + MF F K ++ ++E+ G+L +Q CHKFD
Sbjct: 45 HDNILRMFGYFHDKTRVYLILEFAPKGELYKELQRCHKFD 164
>01707
Length = 757
Score = 74.3 bits (181), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 61/224 (27%), Positives = 103/224 (45%), Gaps = 6/224 (2%)
Frame = +1
Query: 386 LGKGSFGKVFLAEFKKTNQFFAIKAXXXXXXXXXXXXECTMVEKRVLSLAWEHPFLTHMF 445
+G+GS+G VF K+T+Q AIK + M E R+L +HP L +
Sbjct: 88 IGEGSYGVVFKCRNKETSQLVAIKK-FVESEDDPLIKKIAMREIRMLK-QLKHPNLVRLI 261
Query: 446 CTFQTKENLFFVMEYLNG---GDLMYHIQSCHKFDLSRATFYAAEIILGLQFLHSKGIVY 502
F+ K+ L V +Y++ +L + + + + R + + +L + F H ++
Sbjct: 262 EVFRRKKRLHLVFDYVDHTLLNELDRYPRGLPEPMVKRIIY---QTLLAVNFCHQYNTIH 432
Query: 503 RXXXXXXXXXXXXGHIKIADFGMCK-ENMLGDAKTNTFCGTPDYIAPEILLGQ-KYNHSV 560
R G +K+ DFG + GD T+ + T Y APE+L+G +Y V
Sbjct: 433 RDVKPENILITRQGQVKLCDFGFARILTGPGDEYTD-YVATRWYRAPELLVGDTQYGPPV 609
Query: 561 DWWSFGVLLYEMLIGQSPFHGQDEEELFHSIRMD-NPFYPRWLE 603
D W+ G + E+L GQ+ + G+ + + H IR PR +E
Sbjct: 610 DVWAIGCVFAELLTGQALWPGRSDVDQLHLIRKTLGDLIPRHIE 741
>01392
Length = 1806
Score = 73.6 bits (179), Expect = 3e-13, Method: Compositional matrix adjust.
Identities = 58/184 (31%), Positives = 83/184 (45%), Gaps = 32/184 (17%)
Frame = -1
Query: 481 ATFYAAEIILGLQFLHSKGIVYRXXXXXXXXXXXXGHI---KIADFGM-----CKENMLG 532
A+ I L FLHSKGI +R + KI DF + C +
Sbjct: 1785 ASLVVRHIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGISCDGDGTK 1606
Query: 533 DAKTNTFCGTPDYIAPEIL---LGQK--YNHSVDWWSFGVLLYEMLIGQSPFHGQDEEE- 586
+ T G+ +Y+APE++ +G Y+ D WS G++LY ML G PF+GQ E+
Sbjct: 1605 TPELLTPVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILYIMLCGYPPFYGQCGEDC 1426
Query: 587 --------------LFHSIRMDNPFYP--RW--LEKEAKDLLVKLFVREPEKRLGVRGDI 628
LF+SI+ + +P W + AKDL+ L VREP KR D+
Sbjct: 1425 GWNRGEACHDCQDMLFNSIQDGHYKFPSQEWTSISSSAKDLIRHLLVREPRKRYSA-ADV 1249
Query: 629 RQHP 632
+HP
Sbjct: 1248 LKHP 1237
>13212
Length = 1067
Score = 72.0 bits (175), Expect = 9e-13, Method: Compositional matrix adjust.
Identities = 44/157 (28%), Positives = 70/157 (44%), Gaps = 8/157 (5%)
Frame = -1
Query: 487 EIILGLQFLHSKGIVYRXXXXXXXXXXXXGHIKIADFGMCKENMLGDAKTNTFCGTPDYI 546
E+ + L FLH +++R G +K+ADFG+ +N K +TF GTP ++
Sbjct: 956 EMCMALDFLHRHHVIHRDIKAGNVLLTIDGEVKLADFGVSAKNTQTQQKRDTFIGTPYWM 777
Query: 547 APEILL-----GQKYNHSVDWWSFGVLLYEMLIGQSPFHGQDEEELFHSIRMDNPFY--- 598
APE++L Y+ D WS GV L E + P + I +P
Sbjct: 776 APEVVLCETLKDTPYDFKADIWSLGVTLIEFAQIEPPNKEMHPMRVLIKIHKSDPPTLEK 597
Query: 599 PRWLEKEAKDLLVKLFVREPEKRLGVRGDIRQHPLFR 635
P+ K KD + K V++P R ++ +HP +
Sbjct: 596 PKKWTKLFKDFIAKCLVKDPNLR-PTAAELLEHPFMK 489
>14126
Length = 1265
Score = 70.5 bits (171), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 74/292 (25%), Positives = 124/292 (42%), Gaps = 40/292 (13%)
Frame = +3
Query: 385 MLGKGSFGKVFLA-EFKKTNQFFAIKAXXXXXXXXXXXXECTMVEKRVLSL-----AWEH 438
++G G++G V+ A + + +F A+K M+ R +S+ +EH
Sbjct: 210 VIGNGAYGTVYKARDLRNQGEFVAMKRIRLNNTEEG----MPMMAIREISMLKQLEQYEH 377
Query: 439 PFLTHMF----CTFQTKE-NLFFVMEYLNGGDLMYHIQSCHKFDLS--RATFYAAEIILG 491
P + + T +E L V EY+ DL ++ C L R +++ G
Sbjct: 378 PNVVRLLDVSHNTITDREIRLNLVFEYIEH-DLATYLAKCPSPGLGPDRIKDLMLQLLNG 554
Query: 492 LQFLHSKGIVYRXXXXXXXXXXXXGHIKIADFGMCKENMLGDAKTNTFCGTPDYIAPEIL 551
+ FLHS IV+R G +K+ADFG+ + A T T T Y +PE+L
Sbjct: 555 VDFLHSNRIVHRDLKPQNLLISKDGRLKLADFGLARIYSFHMALT-TVVVTLWYRSPEVL 731
Query: 552 LGQKYNHSVDWWSFGVLLYEMLIGQSPFHGQDE----EELFHSIRM-------------D 594
+ +Y SVD WS G + E+ ++ F G E +++F I +
Sbjct: 732 MQAEYGTSVDIWSCGCIFAELFTRRALFKGSSEFDQLKKIFEVIGLPPAGDWPEGVSVHR 911
Query: 595 NPFYPR----------WLEKEAKDLLVKLFVREPEKRLGVRGDIRQHPLFRE 636
N F P ++ +AKDL+ K+ V + +R+ R + HP R+
Sbjct: 912 NSFRPTPPVPLQTLVPEMDPQAKDLMEKMLVFKSGRRISSRESL-LHPYLRD 1064
>25019
Length = 730
Score = 70.5 bits (171), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 28/51 (54%), Positives = 37/51 (72%)
Frame = +3
Query: 516 GHIKIADFGMCKENMLGDAKTNTFCGTPDYIAPEILLGQKYNHSVDWWSFG 566
GH+K+ DFG+CKE + G T+TFCGT +Y+APEIL + +VDWWS G
Sbjct: 285 GHVKLTDFGLCKEAITGTRVTHTFCGTIEYMAPEILTRTGHGKAVDWWSLG 437
>11353
Length = 454
Score = 67.0 bits (162), Expect = 2e-11, Method: Composition-based stats.
Identities = 30/91 (32%), Positives = 46/91 (50%)
Frame = +1
Query: 191 RQCNAAIHKKCIDKVIAKCTGSAINSRETMFHKERFKIDMPHRFKVYNYKSPTFCEHCGT 250
R ++HK+ +++ + G + MF + PHRF+ Y Y +PT+C+ C
Sbjct: 46 RSHGRSVHKRSTLEILVR--GKMLGEAARMFSQ-------PHRFEKYTYTTPTYCDFCQQ 198
Query: 251 LLWGLARQGLKCDACGMNVHHRCQTKVANLC 281
LLWG ++ G C CG N H +CQ V C
Sbjct: 199 LLWGFSKTGTHCVDCGYNCHDKCQPLVPKTC 291
Score = 45.8 bits (107), Expect = 6e-05, Method: Composition-based stats.
Identities = 17/51 (33%), Positives = 23/51 (45%)
Frame = +1
Query: 160 HEFTATFFPQPTFCSVCHEFVWGLNKQGYQCRQCNAAIHKKCIDKVIAKCT 210
H F + PT+C C + +WG +K G C C H KC V C+
Sbjct: 142 HRFEKYTYTTPTYCDFCQQLLWGFSKTGTHCVDCGYNCHDKCQPLVPKTCS 294
>21079
Length = 878
Score = 65.5 bits (158), Expect = 7e-11, Method: Compositional matrix adjust.
Identities = 42/145 (28%), Positives = 71/145 (48%), Gaps = 4/145 (2%)
Frame = +1
Query: 438 HPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSR--ATFYAAEIILGLQFL 495
HP L ++ F+ + VME++ G+L + F L+ + +I G+ ++
Sbjct: 1 HPKLLMLWDAFEAPRTMVLVMEFVGAGELFERVIR-DDFVLTERDCVHFVRQICSGVGYM 177
Query: 496 HSKGIVYRXXXXXXX--XXXXXGHIKIADFGMCKENMLGDAKTNTFCGTPDYIAPEILLG 553
H++ I++ IKI DFG+ + GD+ F GTP++IAPE++
Sbjct: 178 HTQSILHLDLKPENVLCVSDNSNQIKIIDFGLARFYKPGDSLQVLF-GTPEFIAPEVVNY 354
Query: 554 QKYNHSVDWWSFGVLLYEMLIGQSP 578
+ N + D WS GV+ Y +L G SP
Sbjct: 355 DEINFTTDMWSIGVICYILLSGLSP 429
>38560
Length = 479
Score = 63.5 bits (153), Expect = 3e-10, Method: Composition-based stats.
Identities = 37/121 (30%), Positives = 55/121 (45%), Gaps = 5/121 (4%)
Frame = -3
Query: 533 DAKTNTFCGTPDYIAPEILLGQKY-NHSVDWWSFGVLLYEMLIGQSPFHGQDEEELFHSI 591
D T CG+P Y APE++ G +Y D WS GVLLY +L G PF + L
Sbjct: 423 DHHLTTCCGSPAYAAPELISGLEYLGSEADIWSMGVLLYALLCGYLPFDDEKXSHL*QKN 244
Query: 592 RMDNPFYPRWLEKEAKDLLVKLFVREPEKRLGVRGDIRQHPLFREIN----WEELERKEI 647
+ P WL ++ LL + +P R+ +R + H L + N W ++ +
Sbjct: 243 QKRKDEVPEWLSEDTTKLLEGMLQTDPSHRITIRRLLDHHWLNQGFNVPVEWASKYKRTL 64
Query: 648 D 648
D
Sbjct: 63 D 61
>13592
Length = 980
Score = 63.2 bits (152), Expect = 3e-10, Method: Compositional matrix adjust.
Identities = 55/246 (22%), Positives = 99/246 (40%), Gaps = 9/246 (3%)
Frame = +2
Query: 386 LGKGSFGKVFLAEFKKTNQFFAIKAXXXXXXXXXXXXECTMVEKRVLSLAWEHPFLTHMF 445
+G+G FGKV+ A T + A+K + E+ + +H L +
Sbjct: 8 IGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETRALK--NVAEELKILEGIKHKNLVRYY 181
Query: 446 CTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEIILGLQFLHSKGIVYRXX 505
+E L ME + G L ++ + + + A+++ G+ LH GIV+R
Sbjct: 182 GIEVHREELLIFMELCSEGTLESLVELTGGLPEALSRRFTAQLLSGVAELHKHGIVHRDI 361
Query: 506 XXXXXXXXXXGH-IKIADFGMC---KENMLGDAKTNTFCGTPDYIAPEILL---GQKYNH 558
+ +K+ DFG + + + + GT Y+APE+ +
Sbjct: 362 KTANIFLVDGSNSLKLGDFGSAVKIQAHTTVPGELQGYVGTQAYMAPEVFTKTNSDGHGR 541
Query: 559 SVDWWSFGVLLYEMLIGQSPFHGQDE--EELFHSIRMDNPFYPRWLEKEAKDLLVKLFVR 616
D WS G ++ EM G+ P+ D + +F + P P L +E D +
Sbjct: 542 LADIWSVGCVVVEMASGKRPWAQFDSNFQIMFKVGMGEKPQAPESLSQEGHDFIDHCLQH 721
Query: 617 EPEKRL 622
+P++RL
Sbjct: 722 DPKQRL 739
>22804
Length = 967
Score = 62.8 bits (151), Expect = 4e-10, Method: Compositional matrix adjust.
Identities = 29/87 (33%), Positives = 44/87 (50%)
Frame = -3
Query: 196 AIHKKCIDKVIAKCTGSAINSRETMFHKERFKIDMPHRFKVYNYKSPTFCEHCGTLLWGL 255
++HK+ +++ + G + MF PHRF+ Y Y +PT+C+ C LLWG
Sbjct: 911 SVHKRSTLEILVR--GKMLGEAARMF-------SQPHRFEKYTYTTPTYCDFCQQLLWGF 759
Query: 256 ARQGLKCDACGMNVHHRCQTKVANLCG 282
++ G C CG N H +CQ V C
Sbjct: 758 SKTGTHCVDCGYNCHDKCQPLVPKTCS 678
Score = 43.5 bits (101), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 18/53 (33%), Positives = 24/53 (45%)
Frame = -3
Query: 160 HEFTATFFPQPTFCSVCHEFVWGLNKQGYQCRQCNAAIHKKCIDKVIAKCTGS 212
H F + PT+C C + +WG +K G C C H KC V C+ S
Sbjct: 830 HRFEKYTYTTPTYCDFCQQLLWGFSKTGTHCVDCGYNCHDKCQPLVPKTCSKS 672
>21808
Length = 1011
Score = 62.4 bits (150), Expect = 6e-10, Method: Compositional matrix adjust.
Identities = 48/199 (24%), Positives = 81/199 (40%), Gaps = 13/199 (6%)
Frame = +1
Query: 438 HPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHK-FDLSRATFYAAEIILGLQFLH 496
HP L ++ + +F + E + G L+ +Q + L A+I G+ +L
Sbjct: 109 HPKLIQLYAVCTQDDPIFIITELMKNGSLLEFLQGKGRVLKLPALIDIGAQIACGMAYLE 288
Query: 497 SKGIVYRXXXXXXXXXXXXGHIKIADFGMCKENMLGDAKTNTFCGTP-DYIAPEILLGQK 555
S+ ++R +KIADFG+ + + + P + APE +
Sbjct: 289 SQNYIHRDLAARNILVSDNNTVKIADFGLARVIKEDEYEARVGARFPIKWTAPEAANYNR 468
Query: 556 YNHSVDWWSFGVLLYEMLI-GQSPFHGQDEEELFHSI----RM------DNPFYPRWLEK 604
+ D WSFG+LL E + G+ P+ G E+ H + RM P Y LE
Sbjct: 469 FTIKSDVWSFGILLTETVTYGRVPYPGMTNAEVLHQVEHGYRMPCPPGCPKPLYDIMLEC 648
Query: 605 EAKDLLVKLFVREPEKRLG 623
K+ + + +R P G
Sbjct: 649 WRKEEMERPHLRNPAMEAG 705
>13066
Length = 551
Score = 61.6 bits (148), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 37/134 (27%), Positives = 58/134 (43%), Gaps = 4/134 (2%)
Frame = +3
Query: 437 EHPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEIILGLQFLH 496
+HP++ + Q F M + GDL+ +IQ +A + ++ L +LH
Sbjct: 150 DHPYIIQIHSILQRXPKNFIFMRFAERGDLLTYIQEVGFVKEKQAKIWFYQMTTALNYLH 329
Query: 497 SKGIVYRXXXXXXXXXXXXGHIKIADFGM---CKENMLGDAKTNTFCGTPDYIAPEILLG 553
S + +R ++K+ADFG C + T+CG+ Y APEI+ G
Sbjct: 330 SYDVAHRDLKCENILLSSHFNVKLADFGFACACITESGEKYMSRTYCGSAAYAAPEIVYG 509
Query: 554 QKYNHSV-DWWSFG 566
Y V D WS G
Sbjct: 510 APYAPKVADAWSLG 551
>19361
Length = 685
Score = 60.5 bits (145), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 24/58 (41%), Positives = 33/58 (56%)
Frame = -1
Query: 231 PHRFKVYNYKSPTFCEHCGTLLWGLARQGLKCDACGMNVHHRCQTKVANLCGINQKLM 288
PH FKV N+ +CE C +WGL QG+KC CG+ H +C ++ N C N K +
Sbjct: 319 PHVFKVQNFNGLNWCELCANFMWGLIAQGVKCQDCGVQTHKKCSERMPNECMPNMKYV 146
Score = 46.2 bits (108), Expect = 4e-05, Method: Compositional matrix adjust.
Identities = 25/95 (26%), Positives = 40/95 (42%)
Frame = -1
Query: 154 VHHVKCHEFTATFFPQPTFCSVCHEFVWGLNKQGYQCRQCNAAIHKKCIDKVIAKCTGSA 213
+ K H F F +C +C F+WGL QG +C+ C HKKC +++ +C +
Sbjct: 334 TQYEKPHVFKVQNFNGLNWCELCANFMWGLIAQGVKCQDCGVQTHKKCSERMPNECMPNM 155
Query: 214 INSRETMFHKERFKIDMPHRFKVYNYKSPTFCEHC 248
+ K + +D+ K P E C
Sbjct: 154 ------KYVKRLYGVDLTTVTKANKQILPIVVEXC 68
>01756
Length = 1858
Score = 59.3 bits (142), Expect = 6e-09, Method: Compositional matrix adjust.
Identities = 53/213 (24%), Positives = 90/213 (42%), Gaps = 13/213 (6%)
Frame = -3
Query: 386 LGKGSFGKVFLAEFKKTNQFFAIKAXXXXXXXXXXXXECTMVEKRVLSLAWEHPF--LTH 443
+G+G+FG+VF A KKT Q A+K + E ++L L L
Sbjct: 1718 IGQGTFGEVFKARCKKTKQVVAMKKVLMDNEKEGFPI-TALREIKILQLLNHENVVDLIE 1542
Query: 444 MFCTFQTKENLFFVMEYL-------NGGDLMYHIQSCHKFDLSRATFYAAEIILGLQFLH 496
+ T T N + M YL + L+ ++ F+L +++ GL ++H
Sbjct: 1541 ICSTKATSANRYKSMFYLVFEFCEHDLAGLLSNMSVV--FNLPEIKEVMKQLMNGLYYIH 1368
Query: 497 SKGIVYRXXXXXXXXXXXXGHIKIADFGMCKENMLGDAKTNTFCG---TPDYIAPEILLG 553
I++R G +K+ADFG+ + + + N + T Y PE+LLG
Sbjct: 1367 RNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRPPELLLG 1188
Query: 554 QK-YNHSVDWWSFGVLLYEMLIGQSPFHGQDEE 585
+ Y+ ++D W G ++ EM G E+
Sbjct: 1187 DRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQ 1089
>17591
Length = 474
Score = 52.4 bits (124), Expect(2) = 6e-09, Method: Composition-based stats.
Identities = 23/59 (38%), Positives = 35/59 (59%), Gaps = 3/59 (5%)
Frame = +3
Query: 616 REPEKRLGVRGD---IRQHPLFREINWEELERKEIDPPFRPKVKSPFDCSNFDKEFLNE 671
R E+RLG + D I++ F +INW++L K++ PP+ P V D +FD EF+ E
Sbjct: 141 RRKEERLGAKRDFEEIQEKAFFADINWDDLYNKKVQPPYNPNVSGQLDLRHFDPEFVRE 317
Score = 26.6 bits (57), Expect(2) = 6e-09, Method: Composition-based stats.
Identities = 9/22 (40%), Positives = 15/22 (68%)
Frame = +2
Query: 570 YEMLIGQSPFHGQDEEELFHSI 591
+EML G PF+ +D E++ +I
Sbjct: 2 FEMLYGLPPFYSRDTSEMYENI 67
>17932
Length = 597
Score = 43.1 bits (100), Expect(2) = 9e-09, Method: Composition-based stats.
Identities = 30/94 (31%), Positives = 53/94 (56%)
Frame = -3
Query: 602 LEKEAKDLLVKLFVREPEKRLGVRGDIRQHPLFREINWEELERKEIDPPFRPKVKSPFDC 661
+ KEA+DL+ +L + + + RLG +++QHP F+ ++W + + PP+ P + S D
Sbjct: 460 VSKEARDLISQL-LSDGKSRLG-WPELQQHPFFKTVDWANI--RNAMPPYVPSISSLDDT 293
Query: 662 SNFDKEFLNEKPRLSFADRALINSMDQNMFRNFS 695
S+FD+ EK R + I+S Q R+F+
Sbjct: 292 SHFDEV---EKARPA----PNIDSFHQPSSRDFT 212
Score = 35.0 bits (79), Expect(2) = 9e-09, Method: Composition-based stats.
Identities = 13/22 (59%), Positives = 14/22 (63%)
Frame = -2
Query: 562 WWSFGVLLYEMLIGQSPFHGQD 583
WWS GV YEML G +PF D
Sbjct: 596 WWSLGVCAYEMLFGCTPFTDDD 531
>32957
Length = 645
Score = 58.2 bits (139), Expect = 1e-08, Method: Composition-based stats.
Identities = 26/58 (44%), Positives = 36/58 (62%)
Frame = +3
Query: 523 FGMCKENMLGDAKTNTFCGTPDYIAPEILLGQKYNHSVDWWSFGVLLYEMLIGQSPFH 580
F +C E G +T TFCGT +Y+APE+ ++Y VDWW G+LL+E+L Q H
Sbjct: 3 FALCVEKSGG--RTRTFCGTREYMAPEVHERKEYGKEVDWWGLGILLHELLAAQIKKH 170
>04852
Length = 1462
Score = 57.8 bits (138), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 38/120 (31%), Positives = 57/120 (47%), Gaps = 3/120 (2%)
Frame = +1
Query: 484 YAAEIILGLQFLHSKGIVYRXXXXXXXXXXXXGHIKIADFGMCKENMLGDAKTNTFCGT- 542
YA +I G++FL S+ ++R +KIADFG+ + GD G
Sbjct: 340 YAFQIARGMEFLASRKCIHRDLAARNVLVTEEHVLKIADFGLSRT---GDYYKKRSGGRL 510
Query: 543 -PDYIAPEILLGQKYNHSVDWWSFGVLLYEML-IGQSPFHGQDEEELFHSIRMDNPFYPR 600
++APE L +Y D WSFGV+L+E+ +G P+ EEL+ + D PR
Sbjct: 511 PVKWMAPEALFDMRYTTKSDVWSFGVVLWEIFSLGGMPYASIPNEELYSKLLDDAYRMPR 690
>07940
Length = 1336
Score = 57.8 bits (138), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 35/109 (32%), Positives = 56/109 (51%), Gaps = 3/109 (2%)
Frame = -3
Query: 484 YAAEIILGLQFLHSKGIVYRXXXXXXXXXXXXGHIKIADFGMCKENMLGDAKTNTFCGT- 542
YA ++ G+++L SK ++R +KIADFG+ + D T G
Sbjct: 332 YAYQVARGMEYLASKQCIHRDLAARNVLVAEEYVLKIADFGLTRNLQQFDYYRKTTDGRL 153
Query: 543 -PDYIAPEILLGQKYNHSVDWWSFGVLLYEML-IGQSPFHGQDEEELFH 589
++APE L +KY D WS+GVLL+E+ +G +P+ E+LF+
Sbjct: 152 PVKWMAPEALFDRKYTSKSDVWSYGVLLWEIFTLGGNPYPSVPVEDLFN 6
>19094
Length = 898
Score = 57.0 bits (136), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 31/86 (36%), Positives = 44/86 (51%)
Frame = +1
Query: 491 GLQFLHSKGIVYRXXXXXXXXXXXXGHIKIADFGMCKENMLGDAKTNTFCGTPDYIAPEI 550
GL +LHS+ ++R GH K+ADFG+ + AK NT GTP ++APE+
Sbjct: 94 GL*YLHSRRKIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTPYWMAPEV 273
Query: 551 LLGQKYNHSVDWWSFGVLLYEMLIGQ 576
+ Y+ D WS G+ EM G
Sbjct: 274 IQEIGYDCVADIWSLGITALEMAEGN 351
>01718
Length = 959
Score = 56.6 bits (135), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 51/221 (23%), Positives = 91/221 (41%), Gaps = 7/221 (3%)
Frame = +3
Query: 359 LPEPELNKERPSLQIKLKIEDFILHKMLGKGSFGKVFLAEFKKTNQFFAIKAXXXXXXXX 418
LP+ R ++ +++DFI K +G G F +VF + T Q A+K
Sbjct: 93 LPKSSCQALRHAVSALTRLDDFICEK-IGAGFFSEVFKVTHRITGQVMALKMNTMTSNRH 269
Query: 419 XXXXECTMVEKRVLSLAWEHPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQS-CHKFD 477
E ++ + +H + + L + EY+ G+L ++ +
Sbjct: 270 NMLREVQLLNR------LQHANILRFMGVCVHEGQLHALTEYIPSGNLEQLLEKKDEELP 431
Query: 478 LSRATFYAAEIILGLQFLHSKGIVYRXXXXXXXXXXXXG----HIKIADFGMCKE--NML 531
++ + GL +LHS ++R H IADFG+ + + L
Sbjct: 432 WTQRIQLTLGLARGLDYLHSTRFIHRDLTSKNILIRREDNHGYHAVIADFGLATKIPDPL 611
Query: 532 GDAKTNTFCGTPDYIAPEILLGQKYNHSVDWWSFGVLLYEM 572
K T G+P ++APE+L G YN D +S G+++ E+
Sbjct: 612 DKEKLPT-VGSPYWMAPEVLNGHFYNERADLFSVGIIMCEI 731
>20152
Length = 445
Score = 55.8 bits (133), Expect = 6e-08, Method: Composition-based stats.
Identities = 33/87 (37%), Positives = 50/87 (57%), Gaps = 2/87 (2%)
Frame = +1
Query: 548 PEILLGQKYNH-SVDWWSFGVLLYEMLIGQSPFHGQDEEELFHSIRMDNPF-YPRWLEKE 605
PEILLG Y+ +VD WS GV+LY +++G++PF ++ E I MD + P + +
Sbjct: 1 PEILLGDSYDAPAVDVWSLGVILYMLVVGEAPFQEANDSETLTMI-MDCRYQIPPHISHK 177
Query: 606 AKDLLVKLFVREPEKRLGVRGDIRQHP 632
+DL+ K+ REP R + I HP
Sbjct: 178 CQDLIEKMLQREPVDRASLP-HILAHP 255
>35187
Length = 593
Score = 55.5 bits (132), Expect = 7e-08, Method: Composition-based stats.
Identities = 33/119 (27%), Positives = 49/119 (41%)
Frame = -3
Query: 156 HVKCHEFTATFFPQPTFCSVCHEFVWGLNKQGYQCRQCNAAIHKKCIDKVIAKCTGSAIN 215
H H FT F +PT+C C + +WGL GY C CN +H +C+ V++ C+ A
Sbjct: 327 HGHGHFFTKKTFHKPTYCHHCTDILWGLIGVGYVCEVCNFVVHDRCMKTVVSPCSSIA-- 154
Query: 216 SRETMFHKERFKIDMPHRFKVYNYKSPTFCEHCGTLLWGLARQGLKCDACGMNVHHRCQ 274
K + H + + FC C L ++C+ C H CQ
Sbjct: 153 -------TYLIKNPVAHCWSEPGHFKRKFCSVCRKRLED--STAIRCEICEYYAHLDCQ 4
Score = 50.1 bits (118), Expect = 3e-06, Method: Composition-based stats.
Identities = 20/50 (40%), Positives = 25/50 (50%)
Frame = -3
Query: 232 HRFKVYNYKSPTFCEHCGTLLWGLARQGLKCDACGMNVHHRCQTKVANLC 281
H F + PT+C HC +LWGL G C+ C VH RC V + C
Sbjct: 315 HFFTKKTFHKPTYCHHCTDILWGLIGVGYVCEVCNFVVHDRCMKTVVSPC 166
>29581
Length = 1278
Score = 55.1 bits (131), Expect = 9e-08, Method: Compositional matrix adjust.
Identities = 38/132 (28%), Positives = 60/132 (45%), Gaps = 1/132 (0%)
Frame = -2
Query: 449 QTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEIILGLQFLHSKGIVYRXXXXX 508
++ ++LF VMEY F S+ +++ GL++LH I++R
Sbjct: 1139 KSLDSLFLVMEYCEQDLASLLDNMPAPFSESQVKCIVLQLLKGLRYLHEAFIIHRDLKVS 960
Query: 509 XXXXXXXGHIKIADFGMCKENMLGDAKTNTFCGTPDYIAPEILLGQK-YNHSVDWWSFGV 567
G +KIADFG+ + T Y APE+L G K ++ ++D WS G
Sbjct: 959 NLLMTDKGCVKIADFGLARNYGKPQKPMTPKVVTLWYRAPELLFGSKTHSTAIDMWSAGC 780
Query: 568 LLYEMLIGQSPF 579
+L E+L G P
Sbjct: 779 ILGELL-GHKPL 747
>04591
Length = 1117
Score = 54.7 bits (130), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 37/137 (27%), Positives = 66/137 (48%), Gaps = 2/137 (1%)
Frame = -2
Query: 451 KENLFFVMEYLNGGDLMYHIQSCH-KFDLSRATFYAAEIILGLQFLHSKGIVYRXXXXXX 509
K + + EY + DL + + KF L+ ++++ GL ++H+K I++R
Sbjct: 981 KSTFYLIFEYCDY-DLAGLLNNLRVKFSLADKKNLMSQLLNGLFYIHTKQILHRDIKAAN 805
Query: 510 XXXXXXGHIKIADFGMCKENMLGDAKTNTFCGTPDYIAPEILLGQK-YNHSVDWWSFGVL 568
G +K+ADFG+ + + TN T Y PE+LLG++ Y +D W G +
Sbjct: 804 ILLTRDGVLKLADFGLSRPWVKSKRLTNRVV-TLWYRPPELLLGEREYGPEIDMWGVGCI 628
Query: 569 LYEMLIGQSPFHGQDEE 585
+ EM + G+ E+
Sbjct: 627 MAEMWSRKPLMQGRSEQ 577
>00392
Length = 668
Score = 52.0 bits (123), Expect = 8e-07, Method: Compositional matrix adjust.
Identities = 33/151 (21%), Positives = 73/151 (48%), Gaps = 8/151 (5%)
Frame = +3
Query: 437 EHPFLTHMFCTFQ-----TKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEIILG 491
+HP + F ++ ++ + V E + G L +++ K ++ + +++ G
Sbjct: 105 QHPNIVRFFDYWEEHNHRNRKVIILVTELMTSGTLKTYLKRFKKPNVKILKNWCRQVLKG 284
Query: 492 LQFLHSKG--IVYRXXX-XXXXXXXXXGHIKIADFGMCKENMLGDAKTNTFCGTPDYIAP 548
L FLH++ +++R G +KI D G+ + + + GTP+++AP
Sbjct: 285 LYFLHTRTPPVIHRDLKCDNIFITGPTGSVKIGDLGLA--TLKNQSFAKSVIGTPEFMAP 458
Query: 549 EILLGQKYNHSVDWWSFGVLLYEMLIGQSPF 579
E + + Y+ +VD ++FG+ + EM + P+
Sbjct: 459 E-MYEEHYDEAVDVYAFGMCMLEMASSEYPY 548
>02638
Length = 1490
Score = 51.2 bits (121), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 28/99 (28%), Positives = 49/99 (49%), Gaps = 5/99 (5%)
Frame = +1
Query: 541 GTPDYIAPEILLGQKYNHSVDWWSFGVLLYEMLIGQSPFHGQDEEELFHSI-----RMDN 595
GT ++APE+L G+ Y + D WS G ++ EM + P++ D I +D
Sbjct: 22 GTIAFMAPEVLRGESYGRACDVWSVGCVMIEMCTCRPPWNSHDISNHLALIFKIASSVDP 201
Query: 596 PFYPRWLEKEAKDLLVKLFVREPEKRLGVRGDIRQHPLF 634
P P + +DL+++ ++ + R + D+ HPLF
Sbjct: 202 PPIPENMSPPVRDLMLRCLEQDSDFRPSAK-DLLMHPLF 315
>12786
Length = 460
Score = 50.4 bits (119), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 34/122 (27%), Positives = 56/122 (45%), Gaps = 24/122 (19%)
Frame = -3
Query: 483 FYAAEIILGLQFLHSKGIVYRXXXXXXXXXXXXGHIKIADFGMCKENMLGDAKTNTF--- 539
FY E++ ++ LH++G+++ G++K+ DFG+ N L KT+
Sbjct: 398 FYWREMLRAVKALHNEGVIH-SDLKPANFMLVAGNLKLIDFGIA--NTLQQDKTSVLKDS 228
Query: 540 -CGTPDYIAPEILLGQ------------------KYNHSV--DWWSFGVLLYEMLIGQSP 578
GTP Y++PE ++ KY V D WS G +LY M+ G++P
Sbjct: 227 RVGTPSYMSPEAIMAACDDSADDSMEEDGHRTKPKYKVGVRSDVWSLGCILYNMVYGRTP 48
Query: 579 FH 580
F
Sbjct: 47 FQ 42
>01966
Length = 1735
Score = 50.4 bits (119), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 39/119 (32%), Positives = 52/119 (43%), Gaps = 2/119 (1%)
Frame = -1
Query: 452 ENLFFVMEYLNGGDLMYHIQSCHKFDLSRATF--YAAEIILGLQFLHSKGIVYRXXXXXX 509
E LF V E+L+ MY + L R Y +I+ G+ F H + IV+R
Sbjct: 1495 ERLFLVFEFLSMDLKMYIDKFPEGVVLDRRLVKSYVFQIVTGINFCHQRRIVHRDLKPQN 1316
Query: 510 XXXXXXGHIKIADFGMCKENMLGDAKTNTFCGTPDYIAPEILLGQKYNHSVDWWSFGVL 568
G IKIADFGM + L T Y APEIL+G + + W+ G L
Sbjct: 1315 LLINHTGAIKIADFGMARTFALPVRAYTHEVVTLWYRAPEILMGPQ--STPPXWTCGAL 1145
Score = 32.0 bits (71), Expect = 0.79, Method: Compositional matrix adjust.
Identities = 16/42 (38%), Positives = 22/42 (52%), Gaps = 1/42 (2%)
Frame = -3
Query: 553 GQKYNHSVDWWSFGVLLYEMLIGQSPFHGQDE-EELFHSIRM 593
KY+ VD WS G + +MLI F G E ++LF R+
Sbjct: 1184 ASKYSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRI 1059
>11185
Length = 473
Score = 49.7 bits (117), Expect = 4e-06, Method: Composition-based stats.
Identities = 30/117 (25%), Positives = 48/117 (41%), Gaps = 25/117 (21%)
Frame = +1
Query: 484 YAAEIILGLQFLHSKGIVYRXXXXXXXXXXXXGHIKIADFGMCK---------------- 527
+ ++ GL ++HS GI++ G +K ADFG+ K
Sbjct: 16 FGIHLVTGLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEA 195
Query: 528 ---------ENMLGDAKTNTFCGTPDYIAPEILLGQKYNHSVDWWSFGVLLYEMLIG 575
E M+ T+ G+P Y+APE+ G + + D W+ G + YEM G
Sbjct: 196 GDQWNIQSAEEMMKQVPTS---GSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSG 357
>29590
Length = 320
Score = 48.5 bits (114), Expect = 8e-06, Method: Composition-based stats.
Identities = 22/41 (53%), Positives = 26/41 (63%)
Frame = +3
Query: 541 GTPDYIAPEILLGQKYNHSVDWWSFGVLLYEMLIGQSPFHG 581
GTPDY+APE+L + + D WS GVL Y ML SPF G
Sbjct: 60 GTPDYVAPEVLDYEPLSIQTDMWSLGVLSYVMLTACSPFVG 182
>14116
Length = 1017
Score = 48.5 bits (114), Expect = 8e-06, Method: Compositional matrix adjust.
Identities = 32/123 (26%), Positives = 58/123 (47%), Gaps = 4/123 (3%)
Frame = -1
Query: 455 FFVMEYLNGGDLMYHIQSC-HKFDLSRATFYAAEIILGLQFLHSKGIVYRXXXXXXXXXX 513
V+ ++ GDL+ +I+ H+ + Y +I G+ +L V+R
Sbjct: 396 LVVLPFMKHGDLLTYIRDDQHQPTIKDLIMYGVDIARGMDYLAGLKFVHRDLAARNCMLD 217
Query: 514 XXGHIKIADFGMCKENMLGD--AKTNTFCGTP-DYIAPEILLGQKYNHSVDWWSFGVLLY 570
H+K+ADFG+ ++ + + N P ++A E L Y+ D WS+GV+L+
Sbjct: 216 EDFHVKVADFGLARDIYEKEYYSSENKKAKLPVKWMALESLEKGNYDSKTDVWSYGVVLW 37
Query: 571 EML 573
E+L
Sbjct: 36 ELL 28
>27546
Length = 426
Score = 48.1 bits (113), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 24/91 (26%), Positives = 41/91 (45%)
Frame = -1
Query: 437 EHPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEIILGLQFLH 496
+HP + + Q +F M Y GD++ HI+ D ++ + ++ LQ+LH
Sbjct: 306 DHPNIIQIHSILQRGPKIFIFMRYAEKGDMLSHIKKTGPIDEAQTKVWFFQMAKALQYLH 127
Query: 497 SKGIVYRXXXXXXXXXXXXGHIKIADFGMCK 527
S I +R ++KIADFG +
Sbjct: 126 SHDIAHRDLKCENILLSKRLNVKIADFGFAR 34
>09007
Length = 1440
Score = 47.8 bits (112), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 39/159 (24%), Positives = 72/159 (45%), Gaps = 13/159 (8%)
Frame = -1
Query: 476 FDLSRATFYAAEIILGLQFLHSKGIVYRXXXXXXXXXXXXGHIKIADFGMCKENMLGDAK 535
F + R ++ ++ G+ +L SK +V+R +KI+D G+ LG K
Sbjct: 573 FSVPRLCDFSQQVCDGMSYLESKRLVHRDLAARNILLFSKSKVKISDVGV--SGALGAGK 400
Query: 536 -------TNTFCGTPDYIAPEILLGQKYNHSVDWWSFGVLLYEMLI-GQSPFHGQDEEEL 587
T + APE ++ + D W+FGVLL+E G P+ G + +++
Sbjct: 399 EYYQSQQTIHLQNAVAWCAPESFRNLCFSSASDVWAFGVLLWEFFTHGFQPWAGLNGQQI 220
Query: 588 FHSIRMDNPFYPRWLE-----KEAKDLLVKLFVREPEKR 621
++ D P R + KE +++K + +EP++R
Sbjct: 219 MEAV--DAPQSQRLEQPDLCPKEYYAVMLKCWEQEPQRR 109
>08294
Length = 1849
Score = 41.6 bits (96), Expect(2) = 4e-05, Method: Compositional matrix adjust.
Identities = 42/207 (20%), Positives = 81/207 (39%), Gaps = 24/207 (11%)
Frame = +2
Query: 439 PFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHK------------FDLSRATFYAA 486
P + H + E F + EY + GDL + + LS+
Sbjct: 887 PNIVHFMGVCREAEPHFLITEYCDWGDLKQFLLATRNDNGRGRGTRVPALALSQKLGMGQ 1066
Query: 487 EIILGLQFLHSKGIVYRXXXXXXXXXXXXGHIKIADFGMCKENMLGDAKTNTFCGTPD-- 544
++ G++ L ++G+V+ +K+A + + GD + +
Sbjct: 1067 QVAAGMEALSNQGLVHGDLAARNVLLTSRMQLKVA-----RPALSGDVYASEYYPLHQRL 1231
Query: 545 ----YIAPEILLGQKYNHSVDWWSFGVLLYEML-IGQSPFHGQDEEELFHSIR-----MD 594
++ PE +L D W+FGV L+E+L + P+ +EE+ S++ +D
Sbjct: 1232 VPLRWLPPEGVLEDSATTCGDVWAFGVFLWEVLQLADLPYRLMSDEEVLRSLQHSQAALD 1411
Query: 595 NPFYPRWLEKEAKDLLVKLFVREPEKR 621
+P P L LL + ++P +R
Sbjct: 1412 SPDAPPAL----LSLLQRCTAQQPSQR 1480
Score = 24.3 bits (51), Expect(2) = 4e-05, Method: Compositional matrix adjust.
Identities = 9/17 (52%), Positives = 12/17 (70%)
Frame = +1
Query: 385 MLGKGSFGKVFLAEFKK 401
++GKG +G VFLA K
Sbjct: 721 IMGKGCYGDVFLARAKS 771
>26711
Length = 405
Score = 45.8 bits (107), Expect = 6e-05, Method: Composition-based stats.
Identities = 28/97 (28%), Positives = 47/97 (48%), Gaps = 2/97 (2%)
Frame = -2
Query: 492 LQFLHSKGIVYRXXXXXXXXXX--XXGHIKIADFGMCKENMLGDAKTNTFCGTPDYIAPE 549
LQ +H++G+V+ +++ DFG+ ++ + +T GTP + +PE
Sbjct: 377 LQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARK-LYPPQETFLNHGTPGFTSPE 201
Query: 550 ILLGQKYNHSVDWWSFGVLLYEMLIGQSPFHGQDEEE 586
L + + + D W GVL Y +L GQSPF E
Sbjct: 200 ALDVKPISTASDVWGVGVLAYILLSGQSPFQADSATE 90
>28638
Length = 1458
Score = 43.9 bits (102), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 24/62 (38%), Positives = 34/62 (54%)
Frame = -1
Query: 518 IKIADFGMCKENMLGDAKTNTFCGTPDYIAPEILLGQKYNHSVDWWSFGVLLYEMLIGQS 577
IKI DFG LG + + + Y +PE+LLG Y+ ++D WS G +L EM G+
Sbjct: 708 IKIVDFG--SSCQLGQ-RIYQYIQSRFYRSPEVLLGVPYDLAIDMWSLGCILVEMHTGEP 538
Query: 578 PF 579
P
Sbjct: 537 PL 532
>04138
Length = 800
Score = 43.5 bits (101), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 26/98 (26%), Positives = 45/98 (45%), Gaps = 4/98 (4%)
Frame = +1
Query: 492 LQFLHSKGIVYRXXXXXXXXXXXXGHIKIADFGMCKENMLGDAKTNTFCG---TPDYIAP 548
L ++H I++R G +K+ADFG+ + + + N + T Y P
Sbjct: 52 LYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRPP 231
Query: 549 EILLGQK-YNHSVDWWSFGVLLYEMLIGQSPFHGQDEE 585
E+LLG + Y+ ++D W G ++ EM G E+
Sbjct: 232 ELLLGDRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQ 345
>19761
Length = 473
Score = 43.5 bits (101), Expect = 3e-04, Method: Composition-based stats.
Identities = 24/78 (30%), Positives = 39/78 (50%), Gaps = 1/78 (1%)
Frame = -3
Query: 496 HSKGIVYRXXXXXXXXXXXXGHIKIADFGMCKENMLGDAKTNTF-CGTPDYIAPEILLGQ 554
H+ I++R G +++ D G+ ++ + G A T GT Y++PEIL Q
Sbjct: 366 HTPVILHRDLKPQNIYVTEKGDVRLGDLGLARK-LTGPADFATSQVGTIMYLSPEILSQQ 190
Query: 555 KYNHSVDWWSFGVLLYEM 572
YN D WS G + Y++
Sbjct: 189 PYNSKSDIWSLGCVFYDI 136
>37602
Length = 804
Score = 43.1 bits (100), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 28/106 (26%), Positives = 45/106 (42%), Gaps = 7/106 (6%)
Frame = -1
Query: 445 FCTFQTKENLFFVMEYLNGGDL--MYHIQSCHKFDLSRATFYAAEIILGLQFLHSKGIVY 502
F ++ +E L+ MEY GG + +YH+ + F E + GL +LH +G ++
Sbjct: 321 FDSYLRREKLWIAMEYCGGGSMQDIYHVTG--PLTEPQIAFVCRETLKGLHYLHRRGKMH 148
Query: 503 RXXXXXXXXXXXXGHIKIADFGMCKENMLGDAKT-----NTFCGTP 543
R G +K+ADF N + + N F G P
Sbjct: 147 RDIKGANILLTEEGDVKLADFWRVSSNHSHNVQKKVFHWNAFIGWP 10
>12672
Length = 773
Score = 42.0 bits (97), Expect = 8e-04, Method: Compositional matrix adjust.
Identities = 32/114 (28%), Positives = 48/114 (42%), Gaps = 4/114 (3%)
Frame = +3
Query: 491 GLQFLHSKGIVYRXXXXXXXXXXXXGHIKIADFGMCKENMLGDAKT----NTFCGTPDYI 546
G+Q+L+ G V+R K+ DF G+ KT + GT Y+
Sbjct: 27 GIQYLNDNGHVHRDIKTANILLDSEYTAKVGDFATVVSAPSGEGKTVQNASVVIGTAAYL 206
Query: 547 APEILLGQKYNHSVDWWSFGVLLYEMLIGQSPFHGQDEEELFHSIRMDNPFYPR 600
APE + + +D +SFGV+L E++ G EE S M+N P
Sbjct: 207 APE-AIHFDVSTKLDSYSFGVVLLEVITGLVAQDYSREERTLSSHIMENVEEPE 365
>27274
Length = 396
Score = 41.2 bits (95), Expect = 0.001, Method: Composition-based stats.
Identities = 16/31 (51%), Positives = 23/31 (74%)
Frame = -1
Query: 549 EILLGQKYNHSVDWWSFGVLLYEMLIGQSPF 579
E+L GQ++ +VD WS G+LL+E+L G PF
Sbjct: 375 ELLRGQQHGPTVDMWSLGILLHELLSGHVPF 283
>18401
Length = 463
Score = 40.8 bits (94), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 17/50 (34%), Positives = 28/50 (56%)
Frame = -3
Query: 537 NTFCGTPDYIAPEILLGQKYNHSVDWWSFGVLLYEMLIGQSPFHGQDEEE 586
+T T Y APE++L ++H D WS G +++E+ G + F D +E
Sbjct: 458 STIVSTRHYRAPEVILELGWSHPCDVWSVGCIMFELYTGYTLFQTHDNKE 309
>17300
Length = 480
Score = 40.0 bits (92), Expect = 0.003, Method: Composition-based stats.
Identities = 23/78 (29%), Positives = 42/78 (53%), Gaps = 5/78 (6%)
Frame = +1
Query: 519 KIADFGMCKE---NMLGDAKTNTFCGTP-DYIAPEILLGQKYNHSVDWWSFGVLLYE-ML 573
K+ADFG+ +E + A T P + APE + +K+ + D WSFGV+++E M
Sbjct: 94 KVADFGLSREIESDTTEGAYTTKGGKIPVRWTAPEAIAYRKFTSASDVWSFGVVMWEVMS 273
Query: 574 IGQSPFHGQDEEELFHSI 591
G+ P+ +++ ++
Sbjct: 274 YGERPYWNWSNQDVIKAV 327
>17516
Length = 453
Score = 39.7 bits (91), Expect = 0.005, Method: Composition-based stats.
Identities = 17/40 (42%), Positives = 27/40 (67%), Gaps = 1/40 (2%)
Frame = -3
Query: 538 TFCGTPDYIAPEILLGQ-KYNHSVDWWSFGVLLYEMLIGQ 576
T GTP Y+APE+LL + +Y+ D +S ++L+E+ GQ
Sbjct: 442 TLAGTPVYMAPEVLLQKGQYDMKADVYSLAIILWELWYGQ 323
>07291
Length = 833
Score = 39.3 bits (90), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 24/113 (21%), Positives = 50/113 (44%), Gaps = 4/113 (3%)
Frame = +1
Query: 484 YAAEIILGLQFLHSKGIVYRXXXXXXXXXXXXGHIKIADFGMCKENMLGDAKTNTFCGTP 543
+ +I G+ +L +V+R G ++++D+G+ T
Sbjct: 64 FGRQIADGMAYLQEVKVVHRNLAARNCIVTEDGRLQLSDYGVTGSLFPQSYYTADDSPAR 243
Query: 544 D---YIAPEILLGQKYNHSVDWWSFGVLLYEMLI-GQSPFHGQDEEELFHSIR 592
D ++APE + ++ D W+FGV+L+E+L G +P+ + L ++
Sbjct: 244 DLVKWMAPETIDNFHFSSKSDVWAFGVVLWELLTRGITPYPDVENSSLLPYLK 402
>33586
Length = 551
Score = 39.3 bits (90), Expect = 0.006, Method: Composition-based stats.
Identities = 17/49 (34%), Positives = 26/49 (53%)
Frame = +2
Query: 440 FLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEI 488
F+ H+ FQT+ L+ ++E+L GGDL + F FY AE+
Sbjct: 404 FIVHLHYAFQTEGKLYLILEFLRGGDLFTRLSKEVMFTEEDVKFYLAEL 550
>17637
Length = 447
Score = 38.5 bits (88), Expect = 0.010, Method: Compositional matrix adjust.
Identities = 27/91 (29%), Positives = 44/91 (48%), Gaps = 11/91 (12%)
Frame = +1
Query: 518 IKIADFGMCKE------NMLGDAKTNTFCGTPDYIAPEILLGQKYNHSVDWWSFGVLLYE 571
+K+ D + ++ N LGD + +++ E L YN D WSFGVL++E
Sbjct: 28 VKLTDSALSRDLFSGDYNCLGDGEYRPI----KWLSLEALQKSHYNEGSDVWSFGVLMWE 195
Query: 572 M-LIGQSPFHGQDEEELFHSI----RMDNPF 597
M +G+ P+ D E+ H + R+ PF
Sbjct: 196 MCTLGKLPYAEIDPYEMEHYLKDGYRLAQPF 288
>13305
Length = 549
Score = 38.1 bits (87), Expect = 0.012, Method: Composition-based stats.
Identities = 17/45 (37%), Positives = 27/45 (60%), Gaps = 1/45 (2%)
Frame = +2
Query: 545 YIAPEILLGQKYNHSVDWWSFGVLLYEML-IGQSPFHGQDEEELF 588
++A E L Y D WSFGV+L+E+ +G +P+ D ++LF
Sbjct: 23 WMAVESLFNNTYTTQSDVWSFGVVLWEIFTLGGTPYSSTDTQQLF 157
>30743
Length = 569
Score = 37.7 bits (86), Expect = 0.017, Method: Compositional matrix adjust.
Identities = 16/38 (42%), Positives = 23/38 (60%)
Frame = +2
Query: 167 FPQPTFCSVCHEFVWGLNKQGYQCRQCNAAIHKKCIDK 204
F +P C VC + + G+ QGY C+ A+HK+CI K
Sbjct: 347 FEKPKECDVCGKLLRGIFFQGYLCQDNQMAVHKECIGK 460
>20640
Length = 1492
Score = 37.4 bits (85), Expect = 0.019, Method: Compositional matrix adjust.
Identities = 23/78 (29%), Positives = 40/78 (51%), Gaps = 3/78 (3%)
Frame = +1
Query: 518 IKIADFGMCKENMLGDA-KTNTFCGTPDYIAP-EILLGQKYNHSVDWWSFGVLLYEML-I 574
+KI+DFG+ + D + + P P E +L K++ D WSFGV+L+E+
Sbjct: 61 VKISDFGLARSVHSVDYYRGSEHDAIPIRWMPLEAILYNKFSTQSDVWSFGVVLWEIFAF 240
Query: 575 GQSPFHGQDEEELFHSIR 592
P++G EE+ ++
Sbjct: 241 ALQPYYGLTHEEVVRFVK 294
>36002
Length = 253
Score = 37.0 bits (84), Expect = 0.026, Method: Compositional matrix adjust.
Identities = 22/53 (41%), Positives = 30/53 (56%), Gaps = 4/53 (7%)
Frame = +1
Query: 584 EEELFHSIRMDNPFYP--RW--LEKEAKDLLVKLFVREPEKRLGVRGDIRQHP 632
+E LF+ I+ N F+P W + AKDL+ L VREP KR D+ +HP
Sbjct: 49 QELLFNRIQDGNYFFPSMEWSAISSSAKDLIRHLLVREPRKRYSA-ADVLKHP 204
>30339
Length = 384
Score = 34.7 bits (78), Expect = 0.13, Method: Composition-based stats.
Identities = 16/27 (59%), Positives = 19/27 (70%)
Frame = -2
Query: 374 KLKIEDFILHKMLGKGSFGKVFLAEFK 400
+ + DF K+LGKGSFGKV LAE K
Sbjct: 86 RFHLHDFNFIKVLGKGSFGKVMLAERK 6
>17975
Length = 449
Score = 34.3 bits (77), Expect = 0.17, Method: Composition-based stats.
Identities = 23/99 (23%), Positives = 45/99 (45%), Gaps = 2/99 (2%)
Frame = +3
Query: 428 EKRVLSLAWEHPFLTHMFCTFQTKENLFFVMEYLNGGDLM-YHIQSCHKFDLSRATFYAA 486
E R + L +HP + ++ T+ L+ ++E +GGD+ Y ++ + A Y
Sbjct: 114 EVRCMKLV-QHPNVVRLYEVIDTQTKLYLILELGDGGDMYDYIMRHSGGLEEKLAKRYFR 290
Query: 487 EIILGLQFLHSKGIVYRXXX-XXXXXXXXXGHIKIADFG 524
+I+ + + H +V+R G +K+ DFG
Sbjct: 291 QIVEAISYCHKLHVVHRDLKPENVVFFEKPGLVKLTDFG 407
>18996
Length = 491
Score = 32.3 bits (72), Expect = 0.60, Method: Compositional matrix adjust.
Identities = 24/82 (29%), Positives = 40/82 (48%), Gaps = 7/82 (8%)
Frame = +2
Query: 518 IKIADFGMCK-ENMLGDAKTNTFCGTP-DYIAPEILLGQKYNHSVDWWSFGVLLYEM--- 572
+KI+DFG+ + N G + P + +PE + K++ D WS+GV L+EM
Sbjct: 50 VKISDFGLAQFANADGYYYGISQRDIPIKWYSPEAIETCKFSSYSDVWSYGVTLFEMFSR 229
Query: 573 --LIGQSPFHGQDEEELFHSIR 592
+ P H +EE + +R
Sbjct: 230 GEIPNLLPGHDLTQEEFLNRLR 295
>23319
Length = 2235
Score = 31.6 bits (70), Expect = 1.1, Method: Compositional matrix adjust.
Identities = 27/120 (22%), Positives = 46/120 (38%), Gaps = 30/120 (25%)
Frame = +3
Query: 548 PEILLGQKYNHSVDWWSFGVLLYEML-IGQSPFHGQDEEELFHSI--RMDNPFYPRW--- 601
P++ + Y+ S+D WS G + E+ G+ F G D+++ I + P +W
Sbjct: 3 PDVYXAKMYSTSIDMWSAGCIFAELANAGRPLFPGNDDDDQLKRIFKLLGTPTEDQWPGM 182
Query: 602 ------------------------LEKEAKDLLVKLFVREPEKRLGVRGDIRQHPLFREI 637
L + +DLL L V P R+ + QHP F ++
Sbjct: 183 TQLPNYRMFPMYHVTTTWQQVVPKLNSKGRDLLQCLLVCCPSDRMSA-DEALQHPYFADL 359
>26009
Length = 886
Score = 31.6 bits (70), Expect = 1.1, Method: Compositional matrix adjust.
Identities = 27/99 (27%), Positives = 43/99 (43%), Gaps = 6/99 (6%)
Frame = +2
Query: 378 EDFILHKMLGKGSFGKVFLAEFKKTNQFFAIKAXXXXXXXXXXXXECTMVE--KRVLSLA 435
E + + K LG+G++GKV LA + T A+K CT + +R L+
Sbjct: 416 EHYDVCKELGRGTYGKVVLARCRHTGTQVALK---------LLPKSCTKLREFQREFQLS 568
Query: 436 W---EHPFLTHMF-CTFQTKENLFFVMEYLNGGDLMYHI 470
+ H + + FQT+ + F E+ GDL I
Sbjct: 569 YFLSPHANIIDTYNVAFQTRSSYVFAQEHAVLGDLFDAI 685
>26052
Length = 562
Score = 31.2 bits (69), Expect = 1.5, Method: Composition-based stats.
Identities = 13/30 (43%), Positives = 19/30 (63%)
Frame = -1
Query: 380 FILHKMLGKGSFGKVFLAEFKKTNQFFAIK 409
++ K+LG GSFGKV + K T + A+K
Sbjct: 385 YLFXKLLGVGSFGKVMALQHKDTGETLAVK 296
>03294
Length = 1684
Score = 30.0 bits (66), Expect = 3.8, Method: Compositional matrix adjust.
Identities = 15/37 (40%), Positives = 20/37 (54%), Gaps = 1/37 (2%)
Frame = -1
Query: 558 HSVDWWSFGVLLYEMLIGQSPFHGQDE-EELFHSIRM 593
H VD WS G + +MLI F G E ++LF R+
Sbjct: 1678 HPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRI 1568
>13477
Length = 568
Score = 29.3 bits (64), Expect = 6.1, Method: Composition-based stats.
Identities = 12/31 (38%), Positives = 19/31 (61%)
Frame = +3
Query: 455 FFVMEYLNGGDLMYHIQSCHKFDLSRATFYA 485
F V ++L +++ H+QS HKF S T +A
Sbjct: 297 FLVTKWLCTSNILIHLQSAHKFYFSMYTLHA 389
>12041
Length = 575
Score = 28.9 bits (63), Expect = 7.0, Method: Composition-based stats.
Identities = 13/32 (40%), Positives = 18/32 (56%), Gaps = 1/32 (3%)
Frame = -1
Query: 245 CEHCG-TLLWGLARQGLKCDACGMNVHHRCQT 275
C C T+ W +G+ CD CG+ H RCQ+
Sbjct: 278 CGTCDITISW--TEKGVVCDTCGLWFHARCQS 189
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000045065 | hsapiens_gene_ensembl | Poly
[ADP-ribose] polymerase 3 (EC 2.4.2.30) (PARP-3) (NAD(+) ADP-
ribosyltransferase 3) (Poly[ADP-ribose] synthetase 3) (pADPRT-3)
(hPARP-3) (IRT1). [Source:Uniprot/SWISSPROT;Acc:Q9Y6F1]
(533 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
06293 180 9e-57
07234 97 2e-20
10167 60 1e-18
04480 67 1e-11
11193 67 2e-11
32072 41 0.002
05693 28 7.7
>06293
Length = 2053
Score = 180 bits (457), Expect(2) = 9e-57, Method: Compositional matrix adjust.
Identities = 122/384 (31%), Positives = 187/384 (48%), Gaps = 9/384 (2%)
Frame = +2
Query: 24 REEDPFRSTAEALKAIPAEKRIIRVDPTCPLSSNPGTQVYED----YXXXXXXXXXXXXX 79
REE+ T ++ + K VD CPL+ +VYE +
Sbjct: 68 REENGSGDTKSVVRQVVVNKGSAPVDAECPLAGK--CRVYEAASTIWDCMLNQTNVGNNN 241
Query: 80 XKFYIIQLLQD-SNRFFTCWNHWGRVGEVGQSK-INHFTRLEDAKKDFEKKFREKTKNNW 137
K+YIIQ+L+D S + + W WGRVG GQ+ +N L A F KKF++KTKN+W
Sbjct: 242 NKYYIIQVLEDTSKKAYHVWQRWGRVGYKGQTNLVNTGGDLNKAIDVFSKKFQDKTKNHW 421
Query: 138 AERDHFVSHPGKYTLIXXXXXXXXXXXXXXXXRGPVRTVTKRVQPCSLDPATQKLITNIF 197
R++F+ PGKY L+ G + L Q L+ I
Sbjct: 422 NNRNNFLKVPGKYDLVHLDYSAKEEDQVDAGEAGD--NEDSQAPDSKLHQKVQDLVKMIC 595
Query: 198 SKEMFKNTMALMDLDVKKMPLGKLSKQQIARGFXXXXXXXXXXKGPTDGGQSLEELSSHF 257
+ + + M D KK PLGKL+K QI G+ D G++L + S F
Sbjct: 596 DVKSMEEAVVEMKYDAKKAPLGKLTKDQITAGYESLKEIESLI-NTKDFGRNLTDACSEF 772
Query: 258 YTVIPHNFGHSQPPPINSPELLQAKKDMLLVLADIELAQALQAVSEQEKTVEEVPHPLDR 317
YT IPH+FG PP I +P+ ++ K +L L DI+ A++ + + +K+ +P+DR
Sbjct: 773 YTRIPHDFGMRTPPVIRTPKEVKEKLQLLEALEDIQY--AIKMLKQGDKS----ENPVDR 934
Query: 318 DYQLLKCQLQLLDSGAPEYKVIQTYLEQTGS---NHRCPTLQHIWKVNQEGEEDRFQAHS 374
Y L C L LD G+ ++K+I++YL +T + N L ++ V+++GE++R+ +
Sbjct: 935 HYHSLACALSPLDHGSDDFKLIESYLLETHAATHNQYKMKLLELYDVDKQGEKERYLDY- 1111
Query: 375 KLGNRKLLWHGTNMAVVAAILTSG 398
GNR LLWHG+ + A IL G
Sbjct: 1112--GNRMLLWHGSRLTNWAGILGQG 1177
Score = 58.5 bits (140), Expect(2) = 9e-57, Method: Compositional matrix adjust.
Identities = 46/142 (32%), Positives = 67/142 (47%), Gaps = 5/142 (3%)
Frame = +1
Query: 397 SGLRIMPH----SGGRVGKGIYFASENSKSAGYVIGMKCGAHHVGYMFLGEVALGR-EHH 451
SGLRI P +G GKG+YFA +SKSA Y K +VG M L +V+LG
Sbjct: 1171 SGLRIAPPEAPVTGYMFGKGVYFADMSSKSANYCFASK--QKNVGMMLLCDVSLGNINEK 1344
Query: 452 INTDNPSLKSPPPGFDSVIARGHTEPDPTQDTELELDXXXXXXXXXXXXXXXEFSSSTFS 511
++ D + K P G SV G PDP+ + + D T +
Sbjct: 1345 LDADYYADKL-PSGKHSVKGCGSVGPDPST-FKTQPDGLVVPVGKGTNTGVTNPKGYTLN 1518
Query: 512 QSEYLIYQESQCRLRYLLEVHL 533
+E+++Y +Q R++YLL+V
Sbjct: 1519 YNEFIVYNTAQIRMKYLLKVQF 1584
>07234
Length = 543
Score = 97.1 bits (240), Expect = 2e-20, Method: Compositional matrix adjust.
Identities = 65/171 (38%), Positives = 91/171 (53%), Gaps = 7/171 (4%)
Frame = -2
Query: 314 PLDRDYQLLKCQLQLLDSGAPEYKVIQTYLEQT-GSNHRCPTLQ--HIWKVNQEGEEDRF 370
P+D Y+ LKC ++ LD+ +K + Y++ T + H+ TL I+++++EGE +F
Sbjct: 506 PIDAHYKKLKCTMEPLDNKGDMFKRLCEYVQNTHAATHQQYTLDVLDIFEMDREGETQQF 327
Query: 371 QAHSKLGNRKLLWHGTNMAVVAAILTSGLRI----MPHSGGRVGKGIYFASENSKSAGYV 426
+ L NR+LLWHG+ A IL+ GLRI P +G GKGIYFA SKSA Y
Sbjct: 326 EPFKALHNRQLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANYC 147
Query: 427 IGMKCGAHHVGYMFLGEVALGREHHINTDNPSLKSPPPGFDSVIARGHTEP 477
K A +G + L EVALG H + T + P G S G T P
Sbjct: 146 RTSK--ADPIGILLLCEVALGNMHEL-TSASYVTKLPKGKHSTKGIGRTTP 3
>10167
Length = 959
Score = 59.7 bits (143), Expect(2) = 1e-18, Method: Compositional matrix adjust.
Identities = 33/97 (34%), Positives = 55/97 (56%)
Frame = -1
Query: 202 FKNTMALMDLDVKKMPLGKLSKQQIARGFXXXXXXXXXXKGPTDGGQSLEELSSHFYTVI 261
K M ++D+KKMPLGKLSK+QI + Q ++ ++ FYT+I
Sbjct: 611 MKKAMMEFEIDMKKMPLGKLSKRQIESAYKVLTELQDLVTKKGTQTQFVDA-TNRFYTLI 435
Query: 262 PHNFGHSQPPPINSPELLQAKKDMLLVLADIELAQAL 298
PH+FG + +++ E +++K +ML L +IE+A +L
Sbjct: 434 PHDFGMGKIKLLDTEEAIKSKTEMLDNLLEIEVAYSL 324
Score = 51.2 bits (121), Expect(2) = 1e-18, Method: Compositional matrix adjust.
Identities = 31/96 (32%), Positives = 54/96 (56%), Gaps = 6/96 (6%)
Frame = -2
Query: 314 PLDRDYQLLKCQLQLLDSGAPEYKVIQTYLEQT-GSNHRCPTLQ--HIWKVNQEGEEDRF 370
P+D Y+ LKC ++ LD+ +K + Y++ T + H+ TL I+++++EGE +F
Sbjct: 295 PIDAHYKKLKCTMEPLDNKGDMFKRLCEYVQNTHAATHQQYTLDVLDIFEMDREGETQQF 116
Query: 371 QAHSKLGNRKLLWHG---TNMAVVAAILTSGLRIMP 403
+ L NR+LLWHG TN+ + + L + P
Sbjct: 115 EPFKALHNRQLLWHGSRTTNLLASCHRVCASLLLRP 8
Score = 28.9 bits (63), Expect = 5.7, Method: Compositional matrix adjust.
Identities = 13/27 (48%), Positives = 16/27 (59%), Gaps = 4/27 (14%)
Frame = -3
Query: 128 KFRE----KTKNNWAERDHFVSHPGKY 150
KFRE KT N+W +R HF P K+
Sbjct: 819 KFRELYLSKTGNDWEQRKHFKKQPNKF 739
>04480
Length = 1878
Score = 67.4 bits (163), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 58/218 (26%), Positives = 101/218 (46%), Gaps = 4/218 (1%)
Frame = -3
Query: 316 DRDYQLLKCQLQLLDSGAPEYKVIQTYLEQTGSNHRCPTLQHIWKVNQEGEEDRFQAHSK 375
D Y+ + ++Q L E + + TY+ +G H C + ++KV++ GE + +
Sbjct: 1828 DYIYRSMGSKIQPLSENEHETQYLLTYINASG--HGC-KVNAVYKVSRPGEVEALK-DVG 1661
Query: 376 LGNRKLLWHGTNMAVVAAILTSGLRI----MPHSGGRVGKGIYFASENSKSAGYVIGMKC 431
L N +LLWHGT+MA + +IL+ GL + P +G G+G+YFA +KS Y
Sbjct: 1660 LHNHRLLWHGTSMANIVSILSRGLLVAPANAPRNGNAFGEGVYFADCFTKSRSYCYN-AV 1484
Query: 432 GAHHVGYMFLGEVALGREHHINTDNPSLKSPPPGFDSVIARGHTEPDPTQDTELELDXXX 491
G+ V M L +VALG + + S+ G +PDP D ++ L
Sbjct: 1483 GSCKV--MLLCQVALGNSLE-DLCHDEEDHHDEDVHSLKVLGCMQPDP--DFDIVLPYGA 1319
Query: 492 XXXXXXXXXXXXEFSSSTFSQSEYLIYQESQCRLRYLL 529
+ + + +EY+++ Q +RY++
Sbjct: 1318 TLPLGQLKKMTYDGKTPSLQYNEYIVHNPQQICIRYII 1205
>11193
Length = 1001
Score = 67.0 bits (162), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 42/141 (29%), Positives = 65/141 (46%), Gaps = 1/141 (0%)
Frame = -2
Query: 82 FYIIQLL-QDSNRFFTCWNHWGRVGEVGQSKINHFTRLEDAKKDFEKKFREKTKNNWAER 140
FY IQ++ Q + + + WGR+G+ GQ + F EDA K+F K FR+KT N+W
Sbjct: 643 FYKIQIVRQKAKDMYVLFTRWGRIGDRGQWQHTPFPTAEDAIKEFCKVFRQKTGNDWNHL 464
Query: 141 DHFVSHPGKYTLIXXXXXXXXXXXXXXXXRGPVRTVTKRVQPCSLDPATQKLITNIFSKE 200
+ FV H KY L+ + PV + L+P+ L+ + S
Sbjct: 463 EKFVEHKKKYRLMPTLEEPKRSKAVTFNFQSPVAS--------KLNPSVLDLLQELTSVT 308
Query: 201 MFKNTMALMDLDVKKMPLGKL 221
M + + LD MP G++
Sbjct: 307 MLQASAKSKGLDEDFMPFGRI 245
>32072
Length = 272
Score = 40.8 bits (94), Expect = 0.002, Method: Composition-based stats.
Identities = 22/50 (44%), Positives = 29/50 (58%), Gaps = 2/50 (4%)
Frame = +1
Query: 81 KFYIIQLLQD-SNRFFTCWNHWGRVGEVGQSK-INHFTRLEDAKKDFEKK 128
K+YIIQ+L+D S + + W WGRVG GQ+ +N L A F KK
Sbjct: 55 KYYIIQVLEDTSKKAYHVWQRWGRVGYKGQTNLVNTGGDLNKAIDVFSKK 204
>05693
Length = 671
Score = 28.5 bits (62), Expect = 7.7, Method: Compositional matrix adjust.
Identities = 15/46 (32%), Positives = 21/46 (45%), Gaps = 2/46 (4%)
Frame = -2
Query: 373 HSKLGNRKLLWHGTNMAVVAAILTSGLR--IMPHSGGRVGKGIYFA 416
+S + N K LWHGT + I G + G+G+YFA
Sbjct: 574 NSGIQNEKTLWHGTGADAIENINNYGFNRSYCGKNATAFGQGVYFA 437
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000364899 | hsapiens_gene_ensembl |
Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase).
[Source:Uniprot/SWISSPROT;Acc:P43405]
(612 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
06405 217 9e-57
11780 152 1e-56
21808 194 1e-49
14477 182 3e-46
09007 173 2e-43
04852 139 4e-33
07291 129 3e-30
14116 129 5e-30
20640 125 4e-29
17300 115 9e-27
07940 117 2e-26
22005 93 1e-24
18996 103 2e-22
08294 97 1e-20
17637 84 2e-16
18921 82 7e-16
01707 80 3e-15
00715 79 7e-15
13305 79 8e-15
17253 77 3e-14
01718 75 8e-14
13066 69 8e-12
19301 67 2e-11
01756 66 4e-11
12721 66 4e-11
14420 65 6e-11
09606 64 1e-10
21079 63 4e-10
18484 62 9e-10
00300 61 1e-09
01060 61 1e-09
14126 60 2e-09
13212 60 3e-09
31885 58 9e-09
19094 57 3e-08
04591 56 5e-08
29581 55 6e-08
12672 54 1e-07
17806 54 2e-07
27546 50 2e-06
25550 49 2e-06
19761 50 4e-06
07833 50 4e-06
26560 49 6e-06
30755 49 7e-06
27405 47 2e-05
03240 47 3e-05
01966 47 3e-05
15910 46 5e-05
07836 46 5e-05
26711 46 5e-05
28157 45 7e-05
04138 45 1e-04
01392 44 2e-04
11228 43 4e-04
12786 42 6e-04
11185 42 8e-04
10546 41 0.001
30231 40 0.003
13840 39 0.007
21433 38 0.010
04627 38 0.013
35671 38 0.014
00394 37 0.022
18881 36 0.038
18481 36 0.048
31489 35 0.064
31789 35 0.10
14257 34 0.20
26009 33 0.24
16708 33 0.35
38046 33 0.39
21210 32 0.52
15741 32 0.56
36481 32 0.60
18401 32 0.77
00191 32 1.00
29590 31 1.3
25019 30 1.9
02638 30 2.3
37602 30 2.6
07933 30 3.8
14799 30 4.0
30740 28 9.1
>06405
Length = 1965
Score = 217 bits (553), Expect = 9e-57, Method: Compositional matrix adjust.
Identities = 136/412 (33%), Positives = 212/412 (51%), Gaps = 5/412 (1%)
Frame = +1
Query: 201 GSYALCLLHEGKVLHYRIDKDKTGKLSIPEGKKFDTLWQLVEHYSYKADGLLRVLTVPCQ 260
G ++ + EG+V HYRI +D GK+ + + +F+TL +LV H+S ADGL+ L P
Sbjct: 19 GQRSISVRFEGRVYHYRITEDD-GKVFVTQEHRFNTLAELVHHHSIHADGLVTTLLYPAP 195
Query: 261 KIGTQGNVNFGGRPQLPGSHPASSPAQGNRQESTVSFNPYEPELAPWAADKGPQREALPM 320
K RQ+ TV
Sbjct: 196 K----------------------------RQKPTV------------------------- 216
Query: 321 DTEVYESPYADPEEIRPKEVYLDRKLLTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKI 380
SP D EI E+ + +L G G +G V + + K+ K VAVK
Sbjct: 217 ---FGVSPEPDRWEIERTEIAMKHRL--------GGGQYGDVYEAMW--KRYNKIVAVKT 357
Query: 381 LKNEANDPALKDELLAEANVMQQLDNPYIVRMIGICEAES-WMLVMEMAELGPLNKYLQQ 439
LK + AL D L EA +M+++ +P +V+++G+C E + +V E G L YL+
Sbjct: 358 LKEDTM--ALND-FLEEAAIMKEMKHPNLVQLLGVCTREPPFYIVTEFMPHGNLLDYLRS 528
Query: 440 NRHVKDKN----IIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKA 495
+ +++N ++ + Q++ GM YLE NF+HRDLAARN L+ + K++DFGL++
Sbjct: 529 S--TREENGPTALMYMATQIASGMAYLETKNFIHRDLAARNCLVADSNMVKVADFGLARL 702
Query: 496 LRADENYYKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKG 555
++ D Y A K+P+KW APE + + +FS++SD+W+FGVL+WE +YG PY G++
Sbjct: 703 MKDDT--YTAHIGAKFPIKWTAPEGLAFNRFSTRSDIWAFGVLLWELATYGMSPYPGVEL 876
Query: 556 SEVTAMLEKGERMGCPAGCPREMYDLMNLCWTYDVENRPGFAAVELRLRNYY 607
+EV +LE+G RM P G P ++Y LM CW +D ++RP F + L N +
Sbjct: 877 TEVYHLLERGYRMERPPGTPADVYILMLKCWQWDPKDRPTFKEIHFLLENMF 1032
Score = 31.6 bits (70), Expect = 0.86, Method: Compositional matrix adjust.
Identities = 25/84 (29%), Positives = 40/84 (47%), Gaps = 5/84 (5%)
Frame = +1
Query: 43 QSRNYLGGFALSVAHGRKAHHYTIERELNGTYAIAGGRTHASPADLCHYHSQESDGLVCL 102
+S + G ++SV + +HY I E +G + + A+L H+HS +DGLV
Sbjct: 1 ESESSPGQRSISVRFEGRVYHYRIT-EDDGKVFVTQEHRFNTLAELVHHHSIHADGLVTT 177
Query: 103 LKKPFNRPQ-----GVQPKTGPFE 121
L P + Q GV P+ +E
Sbjct: 178 LLYPAPKRQKPTVFGVSPEPDRWE 249
>11780
Length = 1713
Score = 152 bits (384), Expect(2) = 1e-56, Method: Compositional matrix adjust.
Identities = 122/359 (33%), Positives = 166/359 (46%), Gaps = 3/359 (0%)
Frame = +3
Query: 166 MPWFHGKISREESEQIVLIGSKTNGKFLIRARDNN-GSYALCLLHEGKVLHYRIDKDKTG 224
MPWFHGKI+R+++E+ L+ + +G FLIR N G Y LC+ H GKV HYRI +
Sbjct: 249 MPWFHGKITRQQAEE--LLKPREDGLFLIRESSNYPGDYTLCVCHLGKVEHYRILY-REN 419
Query: 225 KLSIPEGKKFDTLWQLVEHYSYKADGLLRVLTVPCQKIGTQGNVNFGGRPQLPGSHPASS 284
+L+I E F L +LV+HY ADGL LT P K G NFG
Sbjct: 420 QLTIDEEGFFRNLDELVKHYLADADGLCTQLTRPVTKQGG----NFG------------- 548
Query: 285 PAQGNRQESTVSFNPYEPELAPWAADKGPQREALPMDTEVYESPYADPEEIRPKEVYLDR 344
TVS ++ W D E+ E+
Sbjct: 549 ---------TVSLQEFKS--GGWVI--------AXQDLEIGEA----------------- 620
Query: 345 KLLTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQL 404
+G G+FG V KG Y+ + VA+K LK++ + L EA+VM L
Sbjct: 621 ---------IGKGDFGDVYKGMYRGQ----PVAIKQLKDKDRG---EQSFLQEASVMTSL 752
Query: 405 DNPYIVRMIGICEAESWMLVMEMAELGPLNKYLQQNRH--VKDKNIIELVHQVSMGMKYL 462
+ +VR+IG+ E+ LV E G L +YL+ + K+ I M+YL
Sbjct: 753 RHDNLVRLIGVVLGETIFLVTEFMGKGNLVEYLRSRGRSVITKKDQINFATDTCAAMEYL 932
Query: 463 EESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECI 521
E VHRDLAARNVL+ AK+SDFGL+K +QT K+P+KW APE +
Sbjct: 933 ESKRLVHRDLAARNVLVHDDGKAKVSDFGLAKFGDF------SQTSVKFPIKWTAPEAL 1091
Score = 87.0 bits (214), Expect(2) = 1e-56, Method: Compositional matrix adjust.
Identities = 38/81 (46%), Positives = 53/81 (65%)
Frame = +1
Query: 525 KFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAGCPREMYDLMNL 584
KF+SKSD+WSFG+L+WE +S+G+ PY + ++V +E+G RM P GCP E+Y +M
Sbjct: 1102 KFTSKSDMWSFGILLWEIYSFGRVPYPRIPLTDVVMHVERGYRMEAPEGCPPEIYSIMKQ 1281
Query: 585 CWTYDVENRPGFAAVELRLRN 605
W D RP F +V RL N
Sbjct: 1282 AWELDPNERPTFKSVLARLNN 1344
Score = 53.5 bits (127), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 43/133 (32%), Positives = 65/133 (48%), Gaps = 1/133 (0%)
Frame = +3
Query: 13 LPFFFGNITREEAEDYLVQGGMSDGLYLLRQSRNYLGGFALSVAHGRKAHHYTI-ERELN 71
+P+F G ITR++AE+ L DGL+L+R+S NY G + L V H K HY I RE
Sbjct: 249 MPWFHGKITRQQAEELLKP--REDGLFLIRESSNYPGDYTLCVCHLGKVEHYRILYRENQ 422
Query: 72 GTYAIAGGRTHASPADLCHYHSQESDGLVCLLKKPFNRPQGVQPKTGPFEDLKENLIREY 131
T G + +L ++ ++DGL L +P V + G F + ++E+
Sbjct: 423 LTIDEEG--FFRNLDELVKHYLADADGLCTQLTRP------VTKQGGNFGTVS---LQEF 569
Query: 132 VKQTWNLQGQALE 144
W + Q LE
Sbjct: 570 KSGGWVIAXQDLE 608
>21808
Length = 1011
Score = 194 bits (492), Expect = 1e-49, Method: Compositional matrix adjust.
Identities = 92/221 (41%), Positives = 146/221 (66%), Gaps = 2/221 (0%)
Frame = +1
Query: 376 VAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRMIGIC-EAESWMLVMEMAELGPLN 434
VA+K LK+ DP + LAEA +M++L +P ++++ +C + + ++ E+ + G L
Sbjct: 28 VAIKTLKSGTMDP---KDFLAEAQIMKKLRHPKLIQLYAVCTQDDPIFIITELMKNGSLL 198
Query: 435 KYLQ-QNRHVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLS 493
++LQ + R +K +I++ Q++ GM YLE N++HRDLAARN+L+ + KI+DFGL+
Sbjct: 199 EFLQGKGRVLKLPALIDIGAQIACGMAYLESQNYIHRDLAARNILVSDNNTVKIADFGLA 378
Query: 494 KALRADENYYKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGM 553
+ ++ DE Y+A+ ++P+KW APE NY +F+ KSDVWSFG+L+ E +YG+ PY GM
Sbjct: 379 RVIKEDE--YEARVGARFPIKWTAPEAANYNRFTIKSDVWSFGILLTETVTYGRVPYPGM 552
Query: 554 KGSEVTAMLEKGERMGCPAGCPREMYDLMNLCWTYDVENRP 594
+EV +E G RM CP GCP+ +YD+M CW + RP
Sbjct: 553 TNAEVLHQVEHGYRMPCPPGCPKPLYDIMLECWRKEEMERP 675
>14477
Length = 493
Score = 182 bits (462), Expect = 3e-46, Method: Compositional matrix adjust.
Identities = 86/160 (53%), Positives = 125/160 (78%)
Frame = -1
Query: 347 LTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQLDN 406
+ +++ +LG+GNFG+V KG ++ VA+K+LKN DP+++ EL+ EA VM+++D+
Sbjct: 487 IQMDELKLGAGNFGSVMKGVCRLDDREIPVAIKVLKNADLDPSVQSELIKEAEVMKKMDH 308
Query: 407 PYIVRMIGICEAESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSMGMKYLEESN 466
+IVR+IG+CE E+ MLV+E+A+LGPLNK+L +N+H+ NI+EL+ QVS GM+YLE +
Sbjct: 307 MHIVRLIGLCEGETMMLVLELAKLGPLNKFLPKNKHLPLWNILELMWQVSQGMEYLEANK 128
Query: 467 FVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQ 506
FVHRDLAARN+LL +H+AKISDFG+SK L + NYY AQ
Sbjct: 127 FVHRDLAARNILLCDEHFAKISDFGMSKTLSRENNYYMAQ 8
>09007
Length = 1440
Score = 173 bits (438), Expect = 2e-43, Method: Compositional matrix adjust.
Identities = 102/265 (38%), Positives = 150/265 (56%), Gaps = 13/265 (4%)
Frame = -1
Query: 352 KELGSGNFGTVKKGYYQMKKVVKT-VAVKILKNEANDPALKD--ELLAEANVMQQLDNPY 408
K LG G+FGTV++ + + K VAVK L + D KD E L E +MQ LD+
Sbjct: 861 KSLGQGHFGTVRQAIWTAESGEKVQVAVKCL---SKDKIHKDGQEFLKETAIMQMLDHEN 691
Query: 409 IVRMIGICEAESWMLVMEMAELGPLNKYLQQNRHVKDK------NIIELVHQVSMGMKYL 462
IVR+ G+ ++ +M + EL P+ L+ + V + + + QV GM YL
Sbjct: 690 IVRVYGVV-MDNGADIMLVTELAPMRSLLECVKEVSARVDFSVPRLCDFSQQVCDGMSYL 514
Query: 463 EESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQ--THGKWPVKWYAPEC 520
E VHRDLAARN+LL ++ KISD G+S AL A + YY++Q H + V W APE
Sbjct: 513 ESKRLVHRDLAARNILLFSKSKVKISDVGVSGALGAGKEYYQSQQTIHLQNAVAWCAPES 334
Query: 521 INYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLE--KGERMGCPAGCPREM 578
FSS SDVW+FGVL+WE F++G +P+ G+ G ++ ++ + +R+ P CP+E
Sbjct: 333 FRNLCFSSASDVWAFGVLLWEFFTHGFQPWAGLNGQQIMEAVDAPQSQRLEQPDLCPKEY 154
Query: 579 YDLMNLCWTYDVENRPGFAAVELRL 603
Y +M CW + + RP F+ + L L
Sbjct: 153 YAVMLKCWEQEPQRRPTFSQLFLTL 79
>04852
Length = 1462
Score = 139 bits (349), Expect = 4e-33, Method: Compositional matrix adjust.
Identities = 85/255 (33%), Positives = 132/255 (51%), Gaps = 32/255 (12%)
Frame = +1
Query: 375 TVAVKILKNEANDPALKDELLAEANVMQQL----DNPYIVRMIGICE--AESWMLVMEMA 428
TVAVK+L++ +D + E VM+ + + IV +G C W++V E A
Sbjct: 25 TVAVKMLRDIVTAVEEQD-FVQELQVMKAVKKMGSHINIVNFLGCCTQGGPLWVIV-EFA 198
Query: 429 ELGPLNKYLQQNRH-------------------------VKDKNIIELVHQVSMGMKYLE 463
+ G L +L+ R ++ KN++ Q++ GM++L
Sbjct: 199 KNGNLRDFLESCRDGINGYGKFVSPQDPGWYTKTPGGHVIRRKNLLSYAFQIARGMEFLA 378
Query: 464 ESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINY 523
+HRDLAARNVL+ +H KI+DFGLS+ +YYK ++ G+ PVKW APE +
Sbjct: 379 SRKCIHRDLAARNVLVTEEHVLKIADFGLSRT----GDYYKKRSGGRLPVKWMAPEALFD 546
Query: 524 YKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEV-TAMLEKGERMGCPAGCPREMYDLM 582
++++KSDVWSFGV++WE FS G PY + E+ + +L+ RM P +Y +M
Sbjct: 547 MRYTTKSDVWSFGVVLWEIFSLGGMPYASIPNEELYSKLLDDAYRMPRPELASGNLYAIM 726
Query: 583 NLCWTYDVENRPGFA 597
CW +RP F+
Sbjct: 727 ERCWLNRPSDRPEFS 771
>07291
Length = 833
Score = 129 bits (324), Expect = 3e-30, Method: Compositional matrix adjust.
Identities = 59/159 (37%), Positives = 94/159 (59%)
Frame = +1
Query: 448 IIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQT 507
+++ Q++ GM YL+E VHR+LAARN ++ ++SD+G++ +L Y +
Sbjct: 55 LLDFGRQIADGMAYLQEVKVVHRNLAARNCIVTEDGRLQLSDYGVTGSLFPQSYYTADDS 234
Query: 508 HGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGER 567
+ VKW APE I+ + FSSKSDVW+FGV++WE + G PY ++ S + L++G R
Sbjct: 235 PARDLVKWMAPETIDNFHFSSKSDVWAFGVVLWELLTRGITPYPDVENSSLLPYLKEGHR 414
Query: 568 MGCPAGCPREMYDLMNLCWTYDVENRPGFAAVELRLRNY 606
M P P +Y++M CW E RP FA + +L+ +
Sbjct: 415 MKKPKQSPEPVYEMMTACWNESPEQRPDFAELNDQLKTF 531
>14116
Length = 1017
Score = 129 bits (323), Expect = 5e-30, Method: Compositional matrix adjust.
Identities = 77/217 (35%), Positives = 119/217 (54%), Gaps = 5/217 (2%)
Frame = -1
Query: 335 IRPKEVYLDRKLLTLEDKELGSGNFGTVKKGYYQM--KKVVKTVAVKILKNEANDPALKD 392
I + + +DR+ LT+ +E+G GNFG VK+G+ + +K VAVK L N
Sbjct: 666 IENESLLIDREFLTM-GEEIGKGNFGCVKRGFLTLPEQKGDILVAVKTLHNNNPREIELQ 490
Query: 393 ELLAEANVMQQLDNPYIVRMIGICEAESWM--LVMEMAELGPLNKYLQQNRHVKD-KNII 449
L EA +M+ + ++ +IGIC M +V+ + G L Y++ ++H K++I
Sbjct: 489 SFLQEALIMKDFHHSNVLTLIGICLNLDDMPLVVLPFMKHGDLLTYIRDDQHQPTIKDLI 310
Query: 450 ELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHG 509
++ GM YL FVHRDLAARN +L + K++DFGL++ + E Y
Sbjct: 309 MYGVDIARGMDYLAGLKFVHRDLAARNCMLDEDFHVKVADFGLARDIYEKEYYSSENKKA 130
Query: 510 KWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYG 546
K PVKW A E + + SK+DVWS+GV++WE + G
Sbjct: 129 KLPVKWMALESLEKGNYDSKTDVWSYGVVLWELLTRG 19
>20640
Length = 1492
Score = 125 bits (315), Expect = 4e-29, Method: Compositional matrix adjust.
Identities = 58/139 (41%), Positives = 84/139 (60%)
Frame = +1
Query: 467 FVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINYYKF 526
+VHRDLA RN L+ KISDFGL++++ + +YY+ H P++W E I Y KF
Sbjct: 7 YVHRDLATRNCLVGHDLVVKISDFGLARSVHS-VDYYRGSEHDAIPIRWMPLEAILYNKF 183
Query: 527 SSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAGCPREMYDLMNLCW 586
S++SDVWSFGV++WE F++ +PY G+ EV +++G+ + CP P MY+LM CW
Sbjct: 184 STQSDVWSFGVVLWEIFAFALQPYYGLTHEEVVRFVKEGKVLACPERTPPPMYELMKQCW 363
Query: 587 TYDVENRPGFAAVELRLRN 605
RP F + L N
Sbjct: 364 HRRPATRPSFHTLHKTLEN 420
>17300
Length = 480
Score = 115 bits (287), Expect(2) = 9e-27, Method: Compositional matrix adjust.
Identities = 57/116 (49%), Positives = 76/116 (65%), Gaps = 2/116 (1%)
Frame = +1
Query: 455 VSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRAD--ENYYKAQTHGKWP 512
+S GM L + +VHRDLAARN+L+ K++DFGLS+ + +D E Y + GK P
Sbjct: 1 ISSGMGXLADMGYVHRDLAARNILVNEILVCKVADFGLSREIESDTTEGAYTTK-GGKIP 177
Query: 513 VKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERM 568
V+W APE I Y KF+S SDVWSFGV+MWE SYG++PY +V +EKG R+
Sbjct: 178 VRWTAPEAIAYRKFTSASDVWSFGVVMWEVMSYGERPYWNWSNQDVIKAVEKGYRL 345
Score = 23.9 bits (50), Expect(2) = 9e-27, Method: Composition-based stats.
Identities = 10/32 (31%), Positives = 16/32 (50%), Gaps = 1/32 (3%)
Frame = +2
Query: 569 GCPA-GCPREMYDLMNLCWTYDVENRPGFAAV 599
CP+ CP ++ LM W + +RP + V
Sbjct: 341 ACPSMDCPEALHQLMLDAWQKERSHRPKMSMV 436
>07940
Length = 1336
Score = 117 bits (292), Expect = 2e-26, Method: Compositional matrix adjust.
Identities = 53/105 (50%), Positives = 75/105 (71%)
Frame = -3
Query: 446 KNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKA 505
K++I +QV+ GM+YL +HRDLAARNVL+ ++ KI+DFGL++ L+ +YY+
Sbjct: 347 KDLISYAYQVARGMEYLASKQCIHRDLAARNVLVAEEYVLKIADFGLTRNLQ-QFDYYRK 171
Query: 506 QTHGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPY 550
T G+ PVKW APE + K++SKSDVWS+GVL+WE F+ G PY
Sbjct: 170 TTDGRLPVKWMAPEALFDRKYTSKSDVWSYGVLLWEIFTLGGNPY 36
>22005
Length = 873
Score = 93.2 bits (230), Expect(2) = 1e-24, Method: Compositional matrix adjust.
Identities = 74/244 (30%), Positives = 118/244 (48%), Gaps = 54/244 (22%)
Frame = +1
Query: 352 KELGSGNFGTVKK-GYYQMKKVVKTVAV--------KILKNEANDPALKDELLAEANVMQ 402
+++G G FG V K + + +V + K+LK +A++ L+ + EA++M
Sbjct: 1 RDIGQGAFGRVSKLKFLGLASLVGELIPEKRP*LL*KMLKEDASED-LQSDFEREASLMA 177
Query: 403 QLDNPYIVRMIGICEAESWM-LVMEMAELGPLNKYLQ--------------QNRHV---- 443
D+P IV+++G+C M L+ E G LN +L+ QN V
Sbjct: 178 DFDHPNIVKLLGVCAIGKPMCLLFEFMSKGDLNDFLRLCSPENYNLPVSRSQNLVVDLED 357
Query: 444 ------------KD--------------KNIIELVHQVSMGMKYLEESNFVHRDLAARNV 477
KD K+ + + Q+S GM YL + ++VHRDLA R V
Sbjct: 358 GLRVEVEAEECEKDTQSEDRDCSGMLXTKDQLYISQQISAGMAYLAQKDYVHRDLATRTV 537
Query: 478 LLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFGV 537
+ ISDFGL++++ + +YY+ P++W E I Y KFS++SDVWSFGV
Sbjct: 538 X-SRTT*S*ISDFGLARSVHS-VDYYRGSEQDAIPIRWMPLEAILYSKFSTQSDVWSFGV 711
Query: 538 LMWE 541
++WE
Sbjct: 712 VLWE 723
Score = 38.5 bits (88), Expect(2) = 1e-24, Method: Compositional matrix adjust.
Identities = 16/53 (30%), Positives = 28/53 (52%)
Frame = +3
Query: 543 FSYGQKPYRGMKGSEVTAMLEKGERMGCPAGCPREMYDLMNLCWTYDVENRPG 595
F++ +PY G+ EV ++ G+ + P P ++Y+LM CW + RP
Sbjct: 726 FAFALQPYYGLTHEEVVNYVKAGKILEQPTKTPHQVYELMKQCW----QRRPA 872
>18996
Length = 491
Score = 103 bits (257), Expect = 2e-22, Method: Compositional matrix adjust.
Identities = 60/137 (43%), Positives = 79/137 (57%), Gaps = 5/137 (3%)
Frame = +2
Query: 468 VHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINYYKFS 527
+HRDLAARN+L V + KISDFGL++ AD YY + P+KWY+PE I KFS
Sbjct: 2 IHRDLAARNIL-VDRSCVKISDFGLAQFANAD-GYYYGISQRDIPIKWYSPEAIETCKFS 175
Query: 528 SKSDVWSFGVLMWEAFSYGQKPY----RGMKGSEVTAMLEKGERMGCPAGCPREMY-DLM 582
S SDVWS+GV ++E FS G+ P + E L KGER+ P C +Y +LM
Sbjct: 176 SYSDVWSYGVTLFEMFSRGEIPNLLPGHDLTQEEFLNRLRKGERLPKPELCSDFVYSELM 355
Query: 583 NLCWTYDVENRPGFAAV 599
CW ++RP F +
Sbjct: 356 RPCWHEMPKSRPTFHQI 406
>08294
Length = 1849
Score = 97.4 bits (241), Expect = 1e-20, Method: Compositional matrix adjust.
Identities = 66/218 (30%), Positives = 96/218 (44%), Gaps = 13/218 (5%)
Frame = +2
Query: 407 PYIVRMIGIC-EAESWMLVMEMAELGPLNKYLQQNRHVKDK------------NIIELVH 453
P IV +G+C EAE L+ E + G L ++L R+ + + +
Sbjct: 887 PNIVHFMGVCREAEPHFLITEYCDWGDLKQFLLATRNDNGRGRGTRVPALALSQKLGMGQ 1066
Query: 454 QVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPV 513
QV+ GM+ L VH DLAARNVLL ++ K++ LS + A E Y Q P+
Sbjct: 1067 QVAAGMEALSNQGLVHGDLAARNVLLTSRMQLKVARPALSGDVYASEYYPLHQR--LVPL 1240
Query: 514 KWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAG 573
+W PE + ++ DVW+FGV +WE PYR M EV L+ +
Sbjct: 1241 RWLPPEGVLEDSATTCGDVWAFGVFLWEVLQLADLPYRLMSDEEVLRSLQHSQAALDSPD 1420
Query: 574 CPREMYDLMNLCWTYDVENRPGFAAVELRLRNYYYDVV 611
P + L+ C RP F+ + L DVV
Sbjct: 1421 APPALLSLLQRCTAQQPSQRPPFSEICSVLSLASTDVV 1534
>17637
Length = 447
Score = 84.0 bits (206), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 43/137 (31%), Positives = 73/137 (53%), Gaps = 1/137 (0%)
Frame = +1
Query: 476 NVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKW-PVKWYAPECINYYKFSSKSDVWS 534
N ++ Q K++D LS+ L + + Y G++ P+KW + E + ++ SDVWS
Sbjct: 1 NCVIDDQLRVKLTDSALSRDLFSGD--YNCLGDGEYRPIKWLSLEALQKSHYNEGSDVWS 174
Query: 535 FGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAGCPREMYDLMNLCWTYDVENRP 594
FGVLMWE + G+ PY + E+ L+ G R+ P CP E++ +M CW RP
Sbjct: 175 FGVLMWEMCTLGKLPYAEIDPYEMEHYLKDGYRLAQPFNCPDELFTIMAYCWASMPAERP 354
Query: 595 GFAAVELRLRNYYYDVV 611
F+ +++ L ++ +
Sbjct: 355 SFSQLQICLSEFHTQIT 405
>18921
Length = 697
Score = 82.0 bits (201), Expect = 7e-16, Method: Compositional matrix adjust.
Identities = 57/192 (29%), Positives = 101/192 (52%), Gaps = 3/192 (1%)
Frame = +2
Query: 353 ELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRM 412
+LG G++G+V K ++ +T V +K D L+ E++ E ++MQQ D+ YIV+
Sbjct: 50 KLGEGSYGSVFKSLHK-----ETGQVLAIKQVPVDTDLQ-EIIKEISIMQQCDSKYIVKY 211
Query: 413 IG--ICEAESWMLVMEMAELGPLNKYLQ-QNRHVKDKNIIELVHQVSMGMKYLEESNFVH 469
G + W +VME G ++ ++ +N+ + ++ I +++ G+ YL +H
Sbjct: 212 YGSYFKNTDLW-IVMEYCGAGSVSDIMRLRNKTLVEREIATILYYTLKGLXYLHSRRKIH 388
Query: 470 RDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINYYKFSSK 529
RD+ A N+LL + +AK++DFG++ L + K T P W APE I +
Sbjct: 389 RDIKAGNILLNNEGHAKLADFGVAGQLT--DTMAKRNTVIGTPY-WMAPEVIQEIGYDCV 559
Query: 530 SDVWSFGVLMWE 541
+D+WS G+ E
Sbjct: 560 ADIWSLGITALE 595
>01707
Length = 757
Score = 80.1 bits (196), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 51/214 (23%), Positives = 105/214 (49%), Gaps = 2/214 (0%)
Frame = +1
Query: 353 ELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRM 412
++G G++G V K + K+ + VA+K +DP +K + E +++QL +P +VR+
Sbjct: 85 KIGEGSYGVVFKC--RNKETSQLVAIKKFVESEDDPLIKKIAMREIRMLKQLKHPNLVRL 258
Query: 413 IGICEAESWM-LVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSMGMKYLEESNFVHRD 471
I + + + LV + + LN+ + R + + + +++Q + + + + N +HRD
Sbjct: 259 IEVFRRKKRLHLVFDYVDHTLLNELDRYPRGLPEPMVKRIIYQTLLAVNFCHQYNTIHRD 438
Query: 472 LAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPE-CINYYKFSSKS 530
+ N+L+ Q K+ DFG ++ L + Y +W + APE + ++
Sbjct: 439 VKPENILITRQGQVKLCDFGFARILTGPGDEYTDYVATRW---YRAPELLVGDTQYGPPV 609
Query: 531 DVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEK 564
DVW+ G + E + GQ + G + ++ K
Sbjct: 610 DVWAIGCVFAELLT-GQALWPGRSDVDQLHLIRK 708
>00715
Length = 1788
Score = 78.6 bits (192), Expect = 7e-15, Method: Compositional matrix adjust.
Identities = 73/259 (28%), Positives = 112/259 (43%), Gaps = 38/259 (14%)
Frame = +1
Query: 374 KTVAVKILKNEANDP-ALK----DELLAEANVMQQLDNPYIVRMIGIC-----EAESWML 423
+TVAVKI +++P AL+ +ELLA ++ ++ +V ++G E +W+
Sbjct: 1 RTVAVKIYHKRSSNPRALRQSYSNELLAFRCGLRHVN---VVSILGATSLHRFEDGAWL- 168
Query: 424 VMEMAELGPLNKYLQQNRHVKDKNI---IELVHQVSMGMKYLEESNFVHRDLAARNVLLV 480
M +GPLN N H +D + + L Q++ G+ YL N VH DL N LL
Sbjct: 169 --AMEYVGPLNLQTILNDHQQDIDSSMRLSLALQMARGLHYLHSINIVHLDLKPANCLLT 342
Query: 481 TQHYAKISDFGLSKALR-------------ADENYYKAQTHGKW------PVKWYAPECI 521
+I+DFG L A G W + + APE +
Sbjct: 343 RDLKLRIADFGCCHQLTPTGLDMGEREGGMAGNELELTPVQGAWKNELAGTLAYRAPELL 522
Query: 522 NYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAGC----PRE 577
+ S +SDV+S G+ +W+ + Q PY G+ V + + CP P E
Sbjct: 523 KGLQPSVRSDVYSLGITLWQMCTR-QGPYEGVPAHAVVYQVVSKDLRPCPPPSTEDDPFE 699
Query: 578 MY--DLMNLCWTYDVENRP 594
+ DL CW VE+RP
Sbjct: 700 VMFRDLYTQCWARRVEDRP 756
>13305
Length = 549
Score = 78.6 bits (192), Expect = 8e-15, Method: Composition-based stats.
Identities = 34/98 (34%), Positives = 54/98 (55%)
Frame = +2
Query: 512 PVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCP 571
P++W A E + ++++SDVWSFGV++WE F+ G PY ++ A L+ G R+ P
Sbjct: 14 PIRWMAVESLFNNTYTTQSDVWSFGVVLWEIFTLGGTPYSSTDTQQLFAFLKDGYRLKRP 193
Query: 572 AGCPREMYDLMNLCWTYDVENRPGFAAVELRLRNYYYD 609
C + Y +M CW + + RP F + RL+ D
Sbjct: 194 KLCDQNTYAMMLQCWNENAQRRPTFPELCGRLQRMLDD 307
>17253
Length = 483
Score = 76.6 bits (187), Expect = 3e-14, Method: Composition-based stats.
Identities = 48/155 (30%), Positives = 82/155 (52%), Gaps = 14/155 (9%)
Frame = -1
Query: 375 TVAVKILKNEANDPALKDELLAEANVMQQLD-NPYIVRMIGICE-AESWMLVMEMAELGP 432
TVAVK NEA A K E L E ++M++L +P +V +G C ++ +++ME G
Sbjct: 462 TVAVKT-HNEAATDAEKSEFLRELSIMRKLPRHPNVVSFMGCCTMSDPALILMEFCCHGD 286
Query: 433 LNKYLQQNR------------HVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLV 480
L +L++ R + ++ V+ GM ++ + VHRD+AARNVL+
Sbjct: 285 LLSFLRKRRPDRTVFLTSTANDLTARDFFSFALHVARGMAHVANNKIVHRDVAARNVLIS 106
Query: 481 TQHYAKISDFGLSKALRADENYYKAQTHGKWPVKW 515
++ K+SDFGLS+ + + Y+ + P++W
Sbjct: 105 ERNVCKVSDFGLSRRVGDQNDVYEIVSRRPLPLRW 1
>01718
Length = 959
Score = 75.1 bits (183), Expect = 8e-14, Method: Compositional matrix adjust.
Identities = 67/265 (25%), Positives = 128/265 (48%), Gaps = 16/265 (6%)
Frame = +3
Query: 352 KELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVR 411
+++G+G F V K +++ V +A+K+ +N + +L E ++ +L + I+R
Sbjct: 165 EKIGAGFFSEVFKVTHRITGQV--MALKMNTMTSN----RHNMLREVQLLNRLQHANILR 326
Query: 412 MIGICEAESWMLVM-EMAELGPLNKYLQQNRHVKDKNI-----IELVHQVSMGMKYLEES 465
+G+C E + + E G L + L++ KD+ + I+L ++ G+ YL +
Sbjct: 327 FMGVCVHEGQLHALTEYIPSGNLEQLLEK----KDEELPWTQRIQLTLGLARGLDYLHST 494
Query: 466 NFVHRDLAARNVLLVTQ----HYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECI 521
F+HRDL ++N+L+ + ++A I+DFGL+ + + K T G W APE +
Sbjct: 495 RFIHRDLTSKNILIRREDNHGYHAVIADFGLATKIPDPLDKEKLPTVGS--PYWMAPEVL 668
Query: 522 NYYKFSSKSDVWSFGVLMWEAFSY-----GQKPYRGMKGSEVTAMLEKGERMGCPAGCPR 576
N + ++ ++D++S G++M E + P G + A+ E + CP
Sbjct: 669 NGHFYNERADLFSVGIIMCEITARIPADPDIMPRMNNFGVDYVALSEM------ISYCPL 830
Query: 577 EMYDLMNLCWTYDVENRP-GFAAVE 600
+ L C D + RP G +E
Sbjct: 831 DYLQLAFKCCQVDPQKRPRGVEIIE 905
>13066
Length = 551
Score = 68.6 bits (166), Expect = 8e-12, Method: Compositional matrix adjust.
Identities = 52/182 (28%), Positives = 86/182 (47%), Gaps = 5/182 (2%)
Frame = +3
Query: 360 GTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLA-EANVMQQLDNPYIVRMIGICE- 417
GT GY + K+ A KI+ E ++ E +++ +LD+PYI+++ I +
Sbjct: 24 GTFNDGYGRNIKL----ACKIIDKEKAPVDFVEKFFPRELDLLTKLDHPYIIQIHSILQR 191
Query: 418 AESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNV 477
+ M AE G L Y+Q+ VK+K +Q++ + YL + HRDL N+
Sbjct: 192 XPKNFIFMRFAERGDLLTYIQEVGFVKEKQAKIWFYQMTTALNYLHSYDVAHRDLKCENI 371
Query: 478 LLVTQHYAKISDFGLSKAL--RADENYYKAQTHGKWPVKWYAPECINYYKFSSK-SDVWS 534
LL + K++DFG + A + E Y G + APE + ++ K +D WS
Sbjct: 372 LLSSHFNVKLADFGFACACITESGEKYMSRTYCGS--AAYAAPEIVYGAPYAPKVADAWS 545
Query: 535 FG 536
G
Sbjct: 546 LG 551
>19301
Length = 712
Score = 67.0 bits (162), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 43/143 (30%), Positives = 73/143 (51%), Gaps = 3/143 (2%)
Frame = +2
Query: 354 LGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANV--MQQLDNPYIVR 411
LGSG G V G K + VAVK +++ + E ++ +++L++P I+
Sbjct: 329 LGSGAQGAVFLG----KLCAEEVAVKKVRD-----------IKETDIRNLRKLNHPNIIS 463
Query: 412 MIGIC-EAESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSMGMKYLEESNFVHR 470
G+C +A + ++ME G L + L+ + + +++ Q++ GM YL +HR
Sbjct: 464 FKGVCTQAPCYCIIMEYCPYGQLYEVLRDGKEIPPALVLDWSKQIASGMNYLHSHKIIHR 643
Query: 471 DLAARNVLLVTQHYAKISDFGLS 493
DL + NVL+ KISDFG S
Sbjct: 644 DLKSPNVLVAKNDVVKISDFGTS 712
>01756
Length = 1858
Score = 66.2 bits (160), Expect = 4e-11, Method: Compositional matrix adjust.
Identities = 51/203 (25%), Positives = 91/203 (44%), Gaps = 11/203 (5%)
Frame = -3
Query: 353 ELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRM 412
++G G FG V K + KK + VA+K + + L E ++Q L++ +V +
Sbjct: 1721 KIGQGTFGEVFKA--RCKKTKQVVAMKKVLMDNEKEGFPITALREIKILQLLNHENVVDL 1548
Query: 413 IGICEAES---------WMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSMGMKYLE 463
I IC ++ + LV E E + I E++ Q+ G+ Y+
Sbjct: 1547 IEICSTKATSANRYKSMFYLVFEFCEHDLAGLLSNMSVVFNLPEIKEVMKQLMNGLYYIH 1368
Query: 464 ESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPE--CI 521
+ +HRD+ A N+L+ Q K++DFGL++A + T+ + WY P +
Sbjct: 1367 RNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTN-RVVTLWYRPPELLL 1191
Query: 522 NYYKFSSKSDVWSFGVLMWEAFS 544
+S+ D W G +M E ++
Sbjct: 1190 GDRNYSTAIDQWGAGCIMAEMWT 1122
>12721
Length = 821
Score = 66.2 bits (160), Expect = 4e-11, Method: Compositional matrix adjust.
Identities = 43/171 (25%), Positives = 76/171 (44%), Gaps = 7/171 (4%)
Frame = +1
Query: 391 KDELLAEANVMQQLDNPYIVRMIG--ICEAESWMLVMEMAELGPLNKYLQQNRHVKDKNI 448
++ L E VM+ +P IV M + E W +VME E G L + NR + + I
Sbjct: 208 RELLFNEVVVMRDYHHPNIVEMYNSYLVNDELW-VVMEFMEGGALTDIVTNNR-MDEVQI 381
Query: 449 IELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTH 508
+ + +L + +HRD+ + ++LL K+ DFG + D K+
Sbjct: 382 ATVCRACLKALAFLHANGVIHRDIKSDSILLSHDGKVKLXDFGFCAQVTQDLQKRKSLVG 561
Query: 509 GKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFS-----YGQKPYRGMK 554
+ W APE I+ + + D+WS G+++ E + + P + M+
Sbjct: 562 TPY---WMAPEVISRLPYGPEVDIWSLGIMVMEMIDAEPPFFNEPPLQAMR 705
>14420
Length = 528
Score = 65.5 bits (158), Expect = 6e-11, Method: Compositional matrix adjust.
Identities = 45/162 (27%), Positives = 78/162 (48%), Gaps = 2/162 (1%)
Frame = +2
Query: 391 KDELLAEANVMQQLDNPYIVRMIG--ICEAESWMLVMEMAELGPLNKYLQQNRHVKDKNI 448
K+ ++ E VM++ NP IV + + E W +VME G L + + + + I
Sbjct: 32 KELIINEILVMRENQNPNIVNYLDSYLVGEELW-VVMEFLAGGSLTDVVTET-CMDEGQI 205
Query: 449 IELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTH 508
+ + +++L E+ +HRD+ + N+LL K++DFG L +++ K T
Sbjct: 206 AAVCRECLQALEFLHENQVIHRDIKSDNILLGMDGSVKLTDFGFCAQLSPEQS--KRSTM 379
Query: 509 GKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPY 550
P W APE + ++ D+WS GV+ E G+ PY
Sbjct: 380 VGTP-YWMAPEVVTRKQYGPTVDIWSLGVMCIEMIE-GEPPY 499
>09606
Length = 1300
Score = 64.3 bits (155), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 55/221 (24%), Positives = 97/221 (43%), Gaps = 20/221 (9%)
Frame = -3
Query: 352 KELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVR 411
+ELG G + KG + K + VA+ ++ + E+ + + +P +V+
Sbjct: 1097 EELGKGEHSIIYKG--RRKGTINFVAIHCIEK-----CKRPEVTNTVRMTHDISHPNVVQ 939
Query: 412 MIGICEAESWM-LVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSMGMKYLEESNFVHR 470
E + + LV+E+ G L L Q+ H+ + +I + + G+ Y+ +
Sbjct: 938 FHEWYETSNHLWLVVELCTGGSLADILAQDHHLPETSIRDFGIHLVTGLHYIHSLGILFH 759
Query: 471 DLAARNVLLVTQHYAKISDFGLSKA--LRADENYYK-AQTHGKWPVK------------- 514
DL VLL T K +DFGLSK +E ++K A+ +W ++
Sbjct: 758 DLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQWNIQSAEEMMKQVPTSG 579
Query: 515 ---WYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRG 552
+ APE + S SD+W+ G + +E FS G P+ G
Sbjct: 578 SPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFS-GHPPFLG 459
>21079
Length = 878
Score = 62.8 bits (151), Expect = 4e-10, Method: Compositional matrix adjust.
Identities = 42/146 (28%), Positives = 75/146 (51%), Gaps = 3/146 (2%)
Frame = +1
Query: 420 SWMLVMEMAELGPL-NKYLQQNRHVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVL 478
+ +LVME G L + ++ + + +++ + V Q+ G+ Y+ + +H DL NVL
Sbjct: 46 TMVLVMEFVGAGELFERVIRDDFVLTERDCVHFVRQICSGVGYMHTQSILHLDLKPENVL 225
Query: 479 LVT--QHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFG 536
V+ + KI DFGL++ + ++ Q P ++ APE +NY + + +D+WS G
Sbjct: 226 CVSDNSNQIKIIDFGLARFYKPGDSL---QVLFGTP-EFIAPEVVNYDEINFTTDMWSIG 393
Query: 537 VLMWEAFSYGQKPYRGMKGSEVTAML 562
V+ + S G+ S VT ML
Sbjct: 394 VICYILLS-------GLSPSRVTTML 450
>18484
Length = 635
Score = 61.6 bits (148), Expect = 9e-10, Method: Compositional matrix adjust.
Identities = 41/150 (27%), Positives = 75/150 (50%), Gaps = 1/150 (0%)
Frame = +1
Query: 437 LQQNRHVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSK-A 495
+QQ K+ ++++G+ +L + ++RDL NV+L ++ + KI+DFG+ K
Sbjct: 16 IQQEGKFKEPVAAFYAAEIAVGLFFLHDQGIIYRDLKLDNVMLDSEGHIKIADFGMCKEG 195
Query: 496 LRADENYYKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKG 555
+ D +T P + APE + Y +S D W++GVL++E + GQ P+ G
Sbjct: 196 MTGDAT---TRTFCGTP-DYIAPEIVLYQPYSKSVDWWAYGVLLFEMLA-GQPPFDGEDE 360
Query: 556 SEVTAMLEKGERMGCPAGCPREMYDLMNLC 585
E+ + + + P RE ++LC
Sbjct: 361 DELFSSITD-HNVSYPKAMSREA---VSLC 438
>00300
Length = 2318
Score = 61.2 bits (147), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 48/246 (19%), Positives = 106/246 (43%), Gaps = 5/246 (2%)
Frame = -1
Query: 353 ELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRM 412
++G G FG V + +A+K +K + ND E+ E + + + + +V+
Sbjct: 1637 KIGEGQFGKVYTAVNM--STGELMALKEMKFQPNDLQQLREMCDEIKIFEGIQHENLVKY 1464
Query: 413 IGI-CEAESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSMGMKYLEESNFVHRD 471
G+ + ++ ME + G + + + + + I ++ + + +L E++ VHRD
Sbjct: 1463 YGVEVHKDEMLMFMEYCDTGTIEEAAKMG--LPEYLIRRYTREIVLAVNHLHENSIVHRD 1290
Query: 472 LAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINYYK---FSS 528
+ N+ L + + K+ DFG S L++ + + APE +
Sbjct: 1289 IKGANIFLTSNGHVKLGDFGCSVKLKSHTTMPGEFHNLVGTTAYMAPEVFTQNDQGGYGR 1110
Query: 529 KSDVWSFGVLMWEAFSYGQKPYRGMKGS-EVTAMLEKGERMGCPAGCPREMYDLMNLCWT 587
+D+WS G ++ E + G++P+ + + ++ + G + P E ++L
Sbjct: 1109 AADIWSLGCVVIE-MATGKRPWHDLDNNYQIMYKVGIGHKPAVPDSLSVEGKHFLDLIMC 933
Query: 588 YDVENR 593
+D R
Sbjct: 932 HDPAQR 915
>01060
Length = 1800
Score = 60.8 bits (146), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 48/192 (25%), Positives = 93/192 (48%), Gaps = 5/192 (2%)
Frame = +1
Query: 352 KELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVR 411
+++G G +G V K + + + +A+K ++ ++ + + E ++++L + IV
Sbjct: 91 QKIGEGTYGVVYKCRH--RATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTNIVC 264
Query: 412 MIG-ICEAESWMLVMEMAELGPLNKYLQQNRH--VKDKNIIE-LVHQVSMGMKYLEESNF 467
+ I E E LV E + L Y+ + V D+ +++ V Q+ G+ + +
Sbjct: 265 LEDVIMEDERLFLVFEFLSMD-LKMYIDKFPEGVVLDRRLVKSYVFQIVTGIXFCHQRRI 441
Query: 468 VHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECI-NYYKF 526
VHRDL +N+L+ KI+DFG+++ Y + W + APE + K+
Sbjct: 442 VHRDLKPQNLLINHTGAIKIADFGMARTFALPVRAYTHEVVTLW---YRAPEILMGASKY 612
Query: 527 SSKSDVWSFGVL 538
S+ DVWS G +
Sbjct: 613 STPVDVWSIGTI 648
>14126
Length = 1265
Score = 60.1 bits (144), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 51/202 (25%), Positives = 103/202 (50%), Gaps = 11/202 (5%)
Frame = +3
Query: 354 LGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQLD---NPYIV 410
+G+G +GTV K ++ + VA+K ++ + + + E ++++QL+ +P +V
Sbjct: 213 IGNGAYGTVYKAR-DLRNQGEFVAMKRIRLNNTEEGMPMMAIREISMLKQLEQYEHPNVV 389
Query: 411 RMIG-----ICEAESWM-LVMEMAELGPLNKYLQQ--NRHVKDKNIIELVHQVSMGMKYL 462
R++ I + E + LV E E L YL + + + I +L+ Q+ G+ +L
Sbjct: 390 RLLDVSHNTITDREIRLNLVFEYIE-HDLATYLAKCPSPGLGPDRIKDLMLQLLNGVDFL 566
Query: 463 EESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECIN 522
+ VHRDL +N+L+ K++DFGL++ +++ A T + + +PE +
Sbjct: 567 HSNRIVHRDLKPQNLLISKDGRLKLADFGLARIY----SFHMALTTVVVTLWYRSPEVLM 734
Query: 523 YYKFSSKSDVWSFGVLMWEAFS 544
++ + D+WS G + E F+
Sbjct: 735 QAEYGTSVDIWSCGCIFAELFT 800
>13212
Length = 1067
Score = 60.1 bits (144), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 45/160 (28%), Positives = 70/160 (43%), Gaps = 9/160 (5%)
Frame = -1
Query: 447 NIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQ 506
I + H++ M + +L + +HRD+ A NVLL K++DFG+S + + K
Sbjct: 977 QICYVCHEMCMALDFLHRHHVIHRDIKAGNVLLTIDGEVKLADFGVSA--KNTQTQQKRD 804
Query: 507 THGKWPVKWYAPECI-------NYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVT 559
T P W APE + Y F K+D+WS GV + E F+ + P + M V
Sbjct: 803 TFIGTPY-WMAPEVVLCETLKDTPYDF--KADIWSLGVTLIE-FAQIEPPNKEMHPMRVL 636
Query: 560 AMLEKGE--RMGCPAGCPREMYDLMNLCWTYDVENRPGFA 597
+ K + + P + D + C D RP A
Sbjct: 635 IKIHKSDPPTLEKPKKWTKLFKDFIAKCLVKDPNLRPTAA 516
>31885
Length = 529
Score = 58.2 bits (139), Expect = 9e-09, Method: Compositional matrix adjust.
Identities = 42/170 (24%), Positives = 82/170 (48%), Gaps = 6/170 (3%)
Frame = -2
Query: 398 ANVMQQLDNPYIVRM-IGICEAESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVS 456
+++ +LD+P++V + + E +V+++ G L ++QQ ++ + + Q++
Sbjct: 519 VDMLTRLDHPFLVNLWYAFQDEEDLFMVVDLFLGGDLRYHMQQEVSFREDCVKFYLCQLA 340
Query: 457 MGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWY 516
+ + YL VHRD+ N+LL Q + ++DF ++ L DE T G P +
Sbjct: 339 LVLDYLRSQKIVHRDIKPDNILLDEQGHCHVTDFNIATQLEDDE--LATSTSGTRP--YM 172
Query: 517 APEC----INYYK-FSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAM 561
APE IN + + D WS GV ++E ++P+ + + M
Sbjct: 171 APEVYGVAINERRGYGFPVDWWSLGVSLFELLK-KRRPFSVHSNTSLHEM 25
>19094
Length = 898
Score = 56.6 bits (135), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 31/103 (30%), Positives = 54/103 (52%)
Frame = +1
Query: 439 QNRHVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRA 498
+N+ + ++ I +++ G+ YL +HRD+ A N+LL + +AK++DFG++ L
Sbjct: 37 RNKTLVEREIATILYYTLKGL*YLHSRRKIHRDIKAGNILLNNEGHAKLADFGVAGQL-- 210
Query: 499 DENYYKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWE 541
+ K T P W APE I + +D+WS G+ E
Sbjct: 211 TDTMAKRNTVIGTPY-WMAPEVIQEIGYDCVADIWSLGITALE 336
>04591
Length = 1117
Score = 55.8 bits (133), Expect = 5e-08, Method: Compositional matrix adjust.
Identities = 55/221 (24%), Positives = 96/221 (43%), Gaps = 14/221 (6%)
Frame = -2
Query: 395 LAEANVMQQLDNPYIVRMIGICEAE---------SWMLVMEMAE--LGPLNKYLQQNRHV 443
L E ++QQL++ +V++ IC + ++ L+ E + L L L+ +
Sbjct: 1077 LREIKILQQLEHENVVQLQEICHTQAGPYNRYKSTFYLIFEYCDYDLAGLLNNLRVKFSL 898
Query: 444 KDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYY 503
DK L+ Q+ G+ Y+ +HRD+ A N+LL K++DFGLS+ +
Sbjct: 897 ADKK--NLMSQLLNGLFYIHTKQILHRDIKAANILLTRDGVLKLADFGLSRP------WV 742
Query: 504 KAQTHGKWPVK-WYAPE--CINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTA 560
K++ V WY P + ++ + D+W G +M E +S +KP M+G
Sbjct: 741 KSKRLTNRVVTLWYRPPELLLGEREYGPEIDMWGVGCIMAEMWS--RKPL--MQGRSEQH 574
Query: 561 MLEKGERMGCPAGCPREMYDLMNLCWTYDVENRPGFAAVEL 601
L + +LC + + E PG +EL
Sbjct: 573 QLSL----------------ITDLCGSLNAEVWPGVTKLEL 499
>29581
Length = 1278
Score = 55.5 bits (132), Expect = 6e-08, Method: Compositional matrix adjust.
Identities = 44/135 (32%), Positives = 65/135 (48%), Gaps = 4/135 (2%)
Frame = -2
Query: 419 ESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVL 478
+S LVME E + + + +V Q+ G++YL E+ +HRDL N+L
Sbjct: 1130 DSLFLVMEYCEQDLASLLDNMPAPFSESQVKCIVLQLLKGLRYLHEAFIIHRDLKVSNLL 951
Query: 479 LVTQHYAKISDFGLSKALRADENYYKAQ--THGKWPVKWY-APECINYYKFSSKS-DVWS 534
+ + KI+DFGL++ NY K Q K WY APE + K S + D+WS
Sbjct: 950 MTDKGCVKIADFGLAR------NYGKPQKPMTPKVVTLWYRAPELLFGSKTHSTAIDMWS 789
Query: 535 FGVLMWEAFSYGQKP 549
G ++ E G KP
Sbjct: 788 AGCILGELL--GHKP 750
>12672
Length = 773
Score = 54.3 bits (129), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 40/159 (25%), Positives = 74/159 (46%), Gaps = 14/159 (8%)
Frame = +3
Query: 450 ELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFG-LSKALRADENYYKAQTH 508
++V + G++YL ++ VHRD+ N+LL +++ AK+ DF + A + + +
Sbjct: 3 KIVKGTASGIQYLNDNGHVHRDIKTANILLDSEYTAKVGDFATVVSAPSGEGKTVQNASV 182
Query: 509 GKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFS--YGQKPYRGMK--GSEVTAMLEK 564
+ APE I ++ S+K D +SFGV++ E + Q R + S + +E+
Sbjct: 183 VIGTAAYLAPEAI-HFDVSTKLDSYSFGVVLLEVITGLVAQDYSREERTLSSHIMENVEE 359
Query: 565 GERM---------GCPAGCPREMYDLMNLCWTYDVENRP 594
E + P G ++YD+ C + RP
Sbjct: 360 PEEIHDFVDQSAGTWPDGAVDKLYDISMRCLNLSKKQRP 476
>17806
Length = 433
Score = 53.9 bits (128), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 43/123 (34%), Positives = 67/123 (54%), Gaps = 12/123 (9%)
Frame = +1
Query: 352 KELGSGNFGTVKKGYYQ--MKKVVKT-VAVKILKNEANDPALKDELLA---EANVMQQLD 405
KELG+G FG V + + V ++ V VK+LK D A KDE L E ++LD
Sbjct: 67 KELGTGWFGKVIESDAERITTGVSRSKVVVKMLK----DDATKDEQLLFFEEVAPFRELD 234
Query: 406 NPYIVRMIGIC-EAESWMLVMEMAELGPLNKYLQQNRH-----VKDKNIIELVHQVSMGM 459
+P IVR++G C E +++ME A LG L +YL+ +RH ++ +++ +S G+
Sbjct: 235 HPNIVRLLGQCTEMNPMLMLMECAALGNLKQYLRNHRHQQAMLIQKNRLLKFAMDISSGL 414
Query: 460 KYL 462
L
Sbjct: 415 ACL 423
>27546
Length = 426
Score = 50.4 bits (119), Expect = 2e-06, Method: Composition-based stats.
Identities = 26/102 (25%), Positives = 52/102 (50%), Gaps = 1/102 (0%)
Frame = -1
Query: 397 EANVMQQLDNPYIVRMIGICE-AESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQV 455
E ++ +LD+P I+++ I + + M AE G + ++++ + + Q+
Sbjct: 330 ELEILTRLDHPNIIQIHSILQRGPKIFIFMRYAEKGDMLSHIKKTGPIDEAQTKVWFFQM 151
Query: 456 SMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALR 497
+ ++YL + HRDL N+LL + KI+DFG ++ R
Sbjct: 150 AKALQYLHSHDIAHRDLKCENILLSKRLNVKIADFGFARYCR 25
>25550
Length = 941
Score = 49.3 bits (116), Expect(2) = 2e-06, Method: Compositional matrix adjust.
Identities = 23/58 (39%), Positives = 33/58 (56%)
Frame = +3
Query: 550 YRGMKGSEVTAMLEKGERMGCPAGCPREMYDLMNLCWTYDVENRPGFAAVELRLRNYY 607
Y G+ +EV +LE+G RM P G P ++Y LM CW +D + RP F + L N +
Sbjct: 42 YPGVDLTEVYHLLERGYRMERPQGTPADVYILMLKCWQWDPKERPTFKEIHYLLENMF 215
Score = 20.4 bits (41), Expect(2) = 2e-06, Method: Compositional matrix adjust.
Identities = 8/17 (47%), Positives = 10/17 (58%)
Frame = +1
Query: 536 GVLMWEAFSYGQKPYRG 552
GVL+WE +YG G
Sbjct: 1 GVLLWELATYGMSLTLG 51
>19761
Length = 473
Score = 49.7 bits (117), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 31/147 (21%), Positives = 69/147 (46%), Gaps = 2/147 (1%)
Frame = -3
Query: 445 DKNIIELVHQVSMGMKYLEESN--FVHRDLAARNVLLVTQHYAKISDFGLSKALRADENY 502
++ I+ + Q + + Y+ +HRDL +N+ + + ++ D GL++ L ++
Sbjct: 426 ERLIVCWLMQTASALNYMHTHTPVILHRDLKPQNIYVTEKGDVRLGDLGLARKLTGPADF 247
Query: 503 YKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAML 562
+Q + + +PE ++ ++SKSD+WS G + ++ G+K M + +
Sbjct: 246 ATSQVG---TIMYLSPEILSQQPYNSKSDIWSLGCVFYDI--TGKKGSDEMGVMFLLVQV 82
Query: 563 EKGERMGCPAGCPREMYDLMNLCWTYD 589
G ++ P +E D ++ T D
Sbjct: 81 MGGRKLPLPDHYSQEFRDTISRMLTKD 1
>07833
Length = 1504
Score = 49.7 bits (117), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 46/218 (21%), Positives = 94/218 (43%), Gaps = 8/218 (3%)
Frame = -3
Query: 390 LKDELLAEANVMQQLDNPYIVRMIGIC-EAESWMLVMEMAELGPLNKYLQ-QNRHVKDKN 447
+ + + E ++ ++P ++ ++ C + + +L+ + G L L ++ V D+N
Sbjct: 1490 ITRDFMEEFPRLRIFNHPNVLPVLACCNQPPNLVLISQFMPFGSLYNTLHGESGIVVDQN 1311
Query: 448 -IIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQ 506
+ ++ GM++L + N LL ++H + D L+ + + +
Sbjct: 1310 QSLRFAMDIARGMEFLHSM-----EPTIPNFLLTSKHV--MIDEDLTARINMADYCFSFH 1152
Query: 507 THGK-WPVKWYAPECINYYK---FSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAML 562
GK + W APE + + +D+WSF +LMWE + P+ + EV +
Sbjct: 1151 EKGKVYSPAWMAPEALQRRPDDINTRAADMWSFAILMWE-LETREVPFAELSSMEVGMKV 975
Query: 563 E-KGERMGCPAGCPREMYDLMNLCWTYDVENRPGFAAV 599
+G R+ P G M L+ +C + RP F +
Sbjct: 974 ALEGLRISIPPGISLHMSRLIKICMNEEPGKRPRFDMI 861
>26560
Length = 398
Score = 48.9 bits (115), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 32/120 (26%), Positives = 59/120 (49%), Gaps = 1/120 (0%)
Frame = -1
Query: 433 LNKYLQQNRHVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGL 492
L+ +L Q+ +K + +V +G++++ V+RDL N+LL + +ISD GL
Sbjct: 395 LHYHLSQHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGL 216
Query: 493 SKALRADENYYKAQTHGKWPVKWYAPECI-NYYKFSSKSDVWSFGVLMWEAFSYGQKPYR 551
+ + THG + APE + + S +D +SFG ++++ G P+R
Sbjct: 215 ACDFSKKRPHASVGTHG-----YMAPEVLMKGQSYDSSADWFSFGCMLYKLLK-GHSPFR 54
>30755
Length = 1137
Score = 48.9 bits (115), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 37/142 (26%), Positives = 61/142 (42%)
Frame = +2
Query: 454 QVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPV 513
++ + YL ++RDL N+LL + K++DFGL K D Y +
Sbjct: 56 EIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCK---EDITYGRTTKTFCGTP 226
Query: 514 KWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAG 573
++ APE ++ + D W GV+M+E G+ P+ + +V L E + P
Sbjct: 227 EYLAPEVLDDNDYGRAVDWWGTGVVMYEMIC-GRLPFYN-RDHDVLFTLILVEDVKFPRN 400
Query: 574 CPREMYDLMNLCWTYDVENRPG 595
E L++ D NR G
Sbjct: 401 ITDEAKSLLSGLLAKDPRNRLG 466
>27405
Length = 532
Score = 47.0 bits (110), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 35/150 (23%), Positives = 70/150 (46%), Gaps = 1/150 (0%)
Frame = -3
Query: 373 VKTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRMIGICEA-ESWMLVMEMAELG 431
+K + K +K + + +E + + V +P+IV M + E ++++ G
Sbjct: 476 MKCLDKKRIKMKGGETLALNERIMLSLVSTGEGSPFIVCMTYAFQTPEKLCFILDLMNGG 297
Query: 432 PLNKYLQQNRHVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFG 491
L+ +L Q+ +K + +V +G++++ V+RDL N+LL + +ISD G
Sbjct: 296 DLHYHLSQHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLG 117
Query: 492 LSKALRADENYYKAQTHGKWPVKWYAPECI 521
L+ + + THG + APE +
Sbjct: 116 LACDFSKKKPHASVGTHG-----YMAPEVL 42
>03240
Length = 1683
Score = 47.0 bits (110), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 48/187 (25%), Positives = 86/187 (45%), Gaps = 11/187 (5%)
Frame = -3
Query: 335 IRPKEVYLDRKLLTLEDKELGSGNFGTV---KKG----YYQMKKVVKTVAVKILKNEAND 387
IR K +D K + + K LG G FG V +K Y MK + K+ +K +N+
Sbjct: 1321 IRLKRAKMD-KCMFEKIKTLGVGAFGEVSLCRKNDTGMLYAMKTLRKSDVLK--RNQVAH 1151
Query: 388 PALKDELLAEANVMQQLDNPYIVRMIGICEAESWM-LVMEMAELGPLNKYLQQNRHVKDK 446
+ ++LAEA DN ++V++ + +++ VM+ G L L + + +
Sbjct: 1150 VKAERDILAEA------DNEWVVKLYYSFQDHNYLYFVMDYVPGGDLMGLLIRMEILDEP 989
Query: 447 NIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADEN---YY 503
V ++ ++ + F+HRD+ N+L+ + K++DFGL R N Y
Sbjct: 988 LARFYVAELVQAIESVHRMGFIHRDIKPDNILIDRNGHIKLTDFGLCTGFRWTHNSKYYQ 809
Query: 504 KAQTHGK 510
+ TH +
Sbjct: 808 RDGTHAR 788
>01966
Length = 1735
Score = 46.6 bits (109), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 40/169 (23%), Positives = 78/169 (46%), Gaps = 4/169 (2%)
Frame = -1
Query: 374 KTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRMIG-ICEAESWMLVMEMAELGP 432
+ +A+K ++ ++ + + E ++++L + IV + I E E LV E +
Sbjct: 1633 RKLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTNIVCLEDVIMEDERLFLVFEFLSMD- 1457
Query: 433 LNKYLQQNRH--VKDKNIIE-LVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISD 489
L Y+ + V D+ +++ V Q+ G+ + + VHRDL +N+L+ KI+D
Sbjct: 1456 LKMYIDKFPEGVVLDRRLVKSYVFQIVTGINFCHQRRIVHRDLKPQNLLINHTGAIKIAD 1277
Query: 490 FGLSKALRADENYYKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFGVL 538
FG+++ Y + W + APE + + S W+ G L
Sbjct: 1276 FGMARTFALPVRAYTHEVVTLW---YRAPEILMGPQ--STPPXWTCGAL 1145
>15910
Length = 1361
Score = 45.8 bits (107), Expect = 5e-05, Method: Compositional matrix adjust.
Identities = 34/125 (27%), Positives = 60/125 (48%), Gaps = 3/125 (2%)
Frame = +2
Query: 445 DKNIIELVHQVSMGMKYLEESNFVHRDLAARNVL---LVTQHYAKISDFGLSKALRADEN 501
+K+ + + G++Y+ + VHRDL N+L + K++DFGLS+ + E
Sbjct: 461 EKDAARAISDILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLADFGLSRII---EP 631
Query: 502 YYKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAM 561
+ T P + APE + K++ D+WS GV+ + G +P+ E+
Sbjct: 632 EVQMSTVCGTP-GYCAPEVLKGDKYTPSVDMWSVGVIAYILLC-GYEPFFAENEFEMYRK 805
Query: 562 LEKGE 566
+ KGE
Sbjct: 806 IIKGE 820
>07836
Length = 1478
Score = 45.8 bits (107), Expect = 5e-05, Method: Compositional matrix adjust.
Identities = 37/140 (26%), Positives = 66/140 (47%), Gaps = 18/140 (12%)
Frame = -1
Query: 420 SW---MLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSMGMKYLEESNF--------V 468
SW L+ + E G L+ YL +R + ++ L H G+ +L F
Sbjct: 1340 SWTQLFLITDYHENGSLHDYLL-SRVLDSSEMLALAHSAICGLAHLHIEIFGTRGKPAIA 1164
Query: 469 HRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWY-APEC----INY 523
HRD+ ++N+L+ I+D GL+ ++ N + + K Y APE +N
Sbjct: 1163 HRDIKSKNILVKKNGTCCIADLGLAVRYISESNEVDVAPNPRQGTKRYMAPEVLEMLLNV 984
Query: 524 YKFSS--KSDVWSFGVLMWE 541
F + ++D+++FG++MWE
Sbjct: 983 KNFDAFKQADMYAFGLVMWE 924
>26711
Length = 405
Score = 45.8 bits (107), Expect = 5e-05, Method: Composition-based stats.
Identities = 33/110 (30%), Positives = 52/110 (47%), Gaps = 3/110 (2%)
Frame = -2
Query: 451 LVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKIS--DFGLSKALRA-DENYYKAQT 507
+V QV ++++ VH DL N+LL + DFGL++ L E + T
Sbjct: 401 VVKQVLDILQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARKLYPPQETFLNHGT 222
Query: 508 HGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSE 557
G + +PE ++ S+ SDVW GVL + S GQ P++ +E
Sbjct: 221 PG-----FTSPEALDVKPISTASDVWGVGVLAYILLS-GQSPFQADSATE 90
>28157
Length = 400
Score = 45.4 bits (106), Expect = 7e-05, Method: Compositional matrix adjust.
Identities = 40/126 (31%), Positives = 61/126 (48%), Gaps = 8/126 (6%)
Frame = +3
Query: 374 KTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRMIGICEAESWMLVMEMAELGPL 433
K VAVK +++E K + E + ++ +P IV + G C LVME AE G L
Sbjct: 3 KDVAVKRIESEQE----KKSFMQELKQLSRVSHPNIVCLYGACRDHPVCLVMEYAEGGSL 170
Query: 434 NKYLQ----QNRHVKDKNIIELVHQVSMGMKYL---EESNFVHRDLAARNVLLV-TQHYA 485
L Q ++ + L+ Q ++G++YL + +HRDL N+LL+
Sbjct: 171 YNVLHGSGPQPQYTAAHAMNWLL-QCALGVEYLHGMKPKALIHRDLKPPNLLLIQCGTKL 347
Query: 486 KISDFG 491
KI DFG
Sbjct: 348 KICDFG 365
>04138
Length = 800
Score = 45.1 bits (105), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 24/86 (27%), Positives = 43/86 (50%), Gaps = 2/86 (2%)
Frame = +1
Query: 461 YLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPE- 519
Y+ + +HRD+ A N+L+ Q K++DFGL++A + T+ + WY P
Sbjct: 58 YIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTN-RVVTLWYRPPE 234
Query: 520 -CINYYKFSSKSDVWSFGVLMWEAFS 544
+ +S+ D W G +M E ++
Sbjct: 235 LLLGDRNYSTAIDQWGAGCIMAEMWT 312
>01392
Length = 1806
Score = 43.9 bits (102), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 30/130 (23%), Positives = 57/130 (43%), Gaps = 13/130 (10%)
Frame = -1
Query: 442 HVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHY-----AKISDFGLSKAL 496
H+ ++ +V ++ + +L HRDL N+L +H KI DF L+ +
Sbjct: 1803 HLCEREASLVVRHIARALDFLHSKGIAHRDLKPENIL--CEHLDDVVPVKICDFDLASGI 1630
Query: 497 RADENYYKAQTHGKWPV---KWYAPECI-----NYYKFSSKSDVWSFGVLMWEAFSYGQK 548
D + K PV ++ APE + + + + + D+WS G++++ G
Sbjct: 1629 SCDGDGTKTPELLT-PVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILYIMLC-GYP 1456
Query: 549 PYRGMKGSEV 558
P+ G G +
Sbjct: 1455 PFYGQCGEDC 1426
>11228
Length = 2155
Score = 42.7 bits (99), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 26/80 (32%), Positives = 41/80 (51%)
Frame = -2
Query: 5 GMADSANHLPFFFGNITREEAEDYLVQGGMSDGLYLLRQSRNYLGGFALSVAHGRKAHHY 64
G + LP+F +++EEA + L+ G +G +L+RQS NY G ++L + +
Sbjct: 1494 GDYEPVESLPYFHSCLSKEEAVEKLMLAG--EGSFLVRQSENYPGDYSLFFLCEKDVRRF 1321
Query: 65 TIERELNGTYAIAGGRTHAS 84
IER G + GGR S
Sbjct: 1320 RIERR--GNQFLVGGRLFDS 1267
>12786
Length = 460
Score = 42.4 bits (98), Expect = 6e-04, Method: Compositional matrix adjust.
Identities = 30/117 (25%), Positives = 50/117 (42%), Gaps = 20/117 (17%)
Frame = -3
Query: 458 GMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYA 517
+K L +H DL N +LV + K+ DFG++ L+ D+ + P + +
Sbjct: 374 AVKALHNEGVIHSDLKPANFMLVAGNL-KLIDFGIANTLQQDKTSVLKDSRVGTP-SYMS 201
Query: 518 PECINY--------------------YKFSSKSDVWSFGVLMWEAFSYGQKPYRGMK 554
PE I YK +SDVWS G +++ YG+ P++ +K
Sbjct: 200 PEAIMAACDDSADDSMEEDGHRTKPKYKVGVRSDVWSLGCILYN-MVYGRTPFQHIK 33
>11185
Length = 473
Score = 42.0 bits (97), Expect = 8e-04, Method: Compositional matrix adjust.
Identities = 32/112 (28%), Positives = 51/112 (45%), Gaps = 19/112 (16%)
Frame = +1
Query: 452 VHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKA--LRADENYYK-AQTH 508
+H V+ G+ Y+ + DL VLL T K +DFGLSK +E ++K A+
Sbjct: 22 IHLVT-GLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAG 198
Query: 509 GKWPVK----------------WYAPECINYYKFSSKSDVWSFGVLMWEAFS 544
+W ++ + APE + S SD+W+ G + +E FS
Sbjct: 199 DQWNIQSAEEMMKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFS 354
>10546
Length = 790
Score = 41.2 bits (95), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 27/86 (31%), Positives = 44/86 (51%), Gaps = 6/86 (6%)
Frame = +2
Query: 165 KMPWFHGKISREESEQIVLIGSKTNGKFLIRARDNNGS--YALCLLHEGKVLHYRIDKDK 222
K W+HG I R + E +V K +G FL+R D + Y L + H+G V + RI
Sbjct: 317 KYEWYHGHIERSKGENLVKHVGK-DGTFLVRVSDKDPKFPYTLVVYHKGSVNNLRIRLRP 493
Query: 223 TGKLSIPEGKK----FDTLWQLVEHY 244
K+++ + KK F + ++EH+
Sbjct: 494 DDKVALGDEKKGEIAFQDVAAMIEHH 571
>30231
Length = 340
Score = 39.7 bits (91), Expect = 0.003, Method: Composition-based stats.
Identities = 30/78 (38%), Positives = 43/78 (55%), Gaps = 8/78 (10%)
Frame = -2
Query: 189 NGKFLIRARDN-NGSYALCLLHEGKVLHYRIDKDKTGKLSI-PEGK----KFDTLWQLVE 242
+G FL+R ++ + +Y LCLL + +V YRI DK G+LS+ EG F L L++
Sbjct: 252 DGSFLVRDSESVSNAYVLCLLFQLRVHQYRILPDKDGRLSVQSEGDMQPLSFIDLPSLIQ 73
Query: 243 HYSYKAD--GLLRVLTVP 258
Y K D GL+ L P
Sbjct: 72 VYISKGDKNGLICPLRRP 19
>13840
Length = 446
Score = 38.9 bits (89), Expect = 0.007, Method: Compositional matrix adjust.
Identities = 36/128 (28%), Positives = 67/128 (52%), Gaps = 8/128 (6%)
Frame = -1
Query: 353 ELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRM 412
E+G GN+GTV K +++ V +AVK +++ + K L+ VM+ + P+IV+
Sbjct: 374 EIGRGNYGTVNKMRHKITSTV--MAVKRIRSTVEEREQKQLLMDLDVVMRSNNCPFIVQF 201
Query: 413 IGIC--EAESWMLVMEMAELGPLNKYLQ----QNRHVKDKNIIELVHQVSM-GMKYL-EE 464
G E + W + ME+ E L+K+ + + + +NI+ + ++ + YL EE
Sbjct: 200 YGALFKEGDCW-ICMELME-TSLDKFYKFVYGEMQSSIPENILGKITVATLKALNYLKEE 27
Query: 465 SNFVHRDL 472
+HRD+
Sbjct: 26 LRIIHRDV 3
>21433
Length = 590
Score = 38.1 bits (87), Expect = 0.010, Method: Composition-based stats.
Identities = 28/98 (28%), Positives = 44/98 (44%)
Frame = +2
Query: 452 VHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKW 511
++Q+S ++Y +HRD+ N+LL + KI+DFG S + T
Sbjct: 185 IYQLSSALEYCHYRKVIHRDIKPENLLLGLKGDLKIADFGWSVHAPSSRRTTMCGT---- 352
Query: 512 PVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKP 549
+ + PE + D+WS GVL +E F G P
Sbjct: 353 -LDYLPPEMVEGKTHDENVDLWSLGVLCYE-FLVGTPP 460
>04627
Length = 572
Score = 37.7 bits (86), Expect = 0.013, Method: Compositional matrix adjust.
Identities = 21/56 (37%), Positives = 30/56 (53%), Gaps = 2/56 (3%)
Frame = +3
Query: 165 KMPWFHGKISREESEQIVLIGSKTNGKFLIRARDNNGS--YALCLLHEGKVLHYRI 218
K W+HG I R + E +V K +G FL+R D + Y L + H+G V + RI
Sbjct: 348 KYEWYHGHIERSKGENLVKHVGK-DGTFLVRVSDKDPKFPYTLVVYHKGSVNNLRI 512
>35671
Length = 567
Score = 37.7 bits (86), Expect = 0.014, Method: Compositional matrix adjust.
Identities = 17/45 (37%), Positives = 22/45 (48%)
Frame = -3
Query: 563 EKGERMGCPAGCPREMYDLMNLCWTYDVENRPGFAAVELRLRNYY 607
+KG R+ P C E Y +M CWT E RP F + + N Y
Sbjct: 565 QKGNRLAKPISCTDEAYKVMLQCWTESREERPTFKKLVPVMENLY 431
>00394
Length = 548
Score = 37.0 bits (84), Expect = 0.022, Method: Compositional matrix adjust.
Identities = 32/103 (31%), Positives = 50/103 (48%), Gaps = 6/103 (5%)
Frame = -2
Query: 343 DRKLLTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQ 402
D + L DKE+G G+F TV KG V VA L+++ + A + EA +++
Sbjct: 304 DNRFLKF-DKEIGRGSFKTVYKGLDTELGV--AVAWCELQDKKWNKAERQRFKEEAEMLK 134
Query: 403 QLDNPYIVRMIGICEAES------WMLVMEMAELGPLNKYLQQ 439
+L +P IVR E + +LV E+ G L YL++
Sbjct: 133 ELQHPNIVRFFDYWEEHNHRNRKVIILVTELMTSGTLKTYLKR 5
>18881
Length = 762
Score = 36.2 bits (82), Expect = 0.038, Method: Compositional matrix adjust.
Identities = 19/58 (32%), Positives = 32/58 (55%), Gaps = 2/58 (3%)
Frame = -3
Query: 189 NGKFLIRARDNNGSYALCLLH--EGKVLHYRIDKDKTGKLSIPEGKKFDTLWQLVEHY 244
+G FLIR N + C + V H +++++ G+ + +G FD++ QLVEHY
Sbjct: 745 DGTFLIRVT-NTSARESCPQY*YANAVRHIKVNRNPQGRFYLADGHYFDSVQQLVEHY 575
>18481
Length = 437
Score = 35.8 bits (81), Expect = 0.048, Method: Composition-based stats.
Identities = 44/129 (34%), Positives = 65/129 (50%), Gaps = 8/129 (6%)
Frame = -1
Query: 374 KTVAVKILKNEANDPALKDELLA-EANVMQQLD-NPYIVRMIGI-CEAESWMLVMEMAEL 430
K +AVKI EA D +K +LL EA V +Q+ +P + M E LVME+ L
Sbjct: 407 KDIAVKI---EAID--VKHQLLHYEAKVYEQIGRHPGLPTMYHYGTEKHFNALVMEL--L 249
Query: 431 GPLNK--YLQQNRHVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQ---HYA 485
GP + ++ R K I+ + Q+ ++++ + F+HRDL N L+ H
Sbjct: 248 GPSLEELFVICKRRFTLKTILMVSDQLLSRLEFIHQKCFIHRDLKPDNFLMGLGRHCHRL 69
Query: 486 KISDFGLSK 494
I DFGLSK
Sbjct: 68 YIIDFGLSK 42
>31489
Length = 329
Score = 35.4 bits (80), Expect = 0.064, Method: Composition-based stats.
Identities = 14/46 (30%), Positives = 30/46 (65%)
Frame = +3
Query: 433 LNKYLQQNRHVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVL 478
L++ + ++ + +++I ++Q+ G+KY+ +N VHRDL N+L
Sbjct: 126 LHRIIYSDQPLTEEHIRYFLYQILRGLKYIHSANVVHRDLKPSNLL 263
>31789
Length = 676
Score = 34.7 bits (78), Expect = 0.10, Method: Compositional matrix adjust.
Identities = 40/151 (26%), Positives = 68/151 (45%), Gaps = 9/151 (5%)
Frame = +2
Query: 318 LPMDTEVYESPYADP-EEIRPKEVYL--DRKLLTLEDKELGSGNFGTVKKGYYQMKKVVK 374
L ++ E+ + A +EI K V D + L D E+G G+F TV KG V
Sbjct: 230 LQLEGEIKDIQQAQKVQEIEEKAVASSPDNRFLKF-DVEIGRGSFKTVYKGLDTELGVA- 403
Query: 375 TVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRMIGICEAES------WMLVMEMA 428
VA L+++ + + EA ++++L +P IVR E + +LV E+
Sbjct: 404 -VAWCELQDKKWNKTERQRFKEEAEMLKELQHPNIVRFFDYWEEHNHRNRKVIILVTELM 580
Query: 429 ELGPLNKYLQQNRHVKDKNIIELVHQVSMGM 459
G L YL++ + + K + Q+ G+
Sbjct: 581 TSGTLKTYLKRFKKINLKVLKNWCRQILKGL 673
>14257
Length = 919
Score = 33.9 bits (76), Expect = 0.20, Method: Compositional matrix adjust.
Identities = 23/83 (27%), Positives = 43/83 (51%), Gaps = 2/83 (2%)
Frame = -3
Query: 168 WFHGKISREESEQIVLIGSKTNGKFLIRARDNNGS-YALCLLHEGKVLH-YRIDKDKTGK 225
W+HGKI R+E+E+++ + +G FL+R N+ + + L G V H +D D +
Sbjct: 890 WYHGKIGRKEAEKLL----ELDGDFLVREASNSAAQFVLSGRQNGNVRHLLLVDPDGIVR 723
Query: 226 LSIPEGKKFDTLWQLVEHYSYKA 248
+ FD++ L+ ++ A
Sbjct: 722 ---TKDFIFDSVSHLINYHRQNA 663
>26009
Length = 886
Score = 33.5 bits (75), Expect = 0.24, Method: Compositional matrix adjust.
Identities = 11/51 (21%), Positives = 28/51 (54%)
Frame = +3
Query: 438 QQNRHVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKIS 488
++N+ + ++ Q+ + ++ VHRD+ NVL++T ++++S
Sbjct: 687 RRNKACGSREAKSVMKQLVSALDFMHSKQLVHRDIKPENVLILTPDFSRVS 839
>16708
Length = 1397
Score = 33.1 bits (74), Expect = 0.35, Method: Compositional matrix adjust.
Identities = 27/118 (22%), Positives = 52/118 (44%), Gaps = 11/118 (9%)
Frame = -1
Query: 423 LVMEMAELGPL-NKYLQQNRHVKDKN----------IIELVHQVSMGMKYLEESNFVHRD 471
+++ E+GPL N Y H K+K + + Q ++++ E VH D
Sbjct: 1184 ILLHFYEMGPLCNVY----AHYKNKEMPIRWSNPAMVCCIAGQXVCALEHIHELGVVHMD 1017
Query: 472 LAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINYYKFSSK 529
+ A NVL+ K++D+G+++ + Y A P + ++ C N F ++
Sbjct: 1016 VKADNVLVDAHGNCKLTDYGIAQLYKV----YPA------PTETHSSGCTNKRTFYTR 873
>38046
Length = 446
Score = 32.7 bits (73), Expect = 0.39, Method: Composition-based stats.
Identities = 11/25 (44%), Positives = 19/25 (76%)
Frame = -1
Query: 455 VSMGMKYLEESNFVHRDLAARNVLL 479
++ M Y+E+ NF+HR+L RN+L+
Sbjct: 98 IADAMAYMEKENFIHRNLGDRNILV 24
>21210
Length = 518
Score = 32.3 bits (72), Expect = 0.52, Method: Compositional matrix adjust.
Identities = 25/91 (27%), Positives = 42/91 (46%), Gaps = 9/91 (9%)
Frame = +3
Query: 515 WYAPECIN----YYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGC 570
+ APE I+ + + +SDVWS G+ + E + G+ PYR K + L++ R
Sbjct: 18 YMAPERIDPRASSHGYDVRSDVWSLGITLME-LATGRFPYR--KWVSIFDQLQQVVRGVA 188
Query: 571 PA-----GCPREMYDLMNLCWTYDVENRPGF 596
P + + +N C T D + RP +
Sbjct: 189 PCLPHDGAFSHDFVNFVNKCLTKDEKQRPKY 281
>15741
Length = 402
Score = 32.3 bits (72), Expect = 0.56, Method: Composition-based stats.
Identities = 13/33 (39%), Positives = 20/33 (60%)
Frame = -3
Query: 446 KNIIELVHQVSMGMKYLEESNFVHRDLAARNVL 478
++ V+ GM ++ + VHRD+AARNVL
Sbjct: 100 RDFFSFALHVARGMAHVANNKIVHRDVAARNVL 2
>36481
Length = 806
Score = 32.3 bits (72), Expect = 0.60, Method: Compositional matrix adjust.
Identities = 38/152 (25%), Positives = 67/152 (44%), Gaps = 19/152 (12%)
Frame = +2
Query: 355 GSGNFGTVKKGYYQMKKVVK--TVAVKILKNEANDPALKDELLAEANVMQQL--DNPY-- 408
G G FG V Q K ++K +A+KI+KN ++ E NV+++L +P+
Sbjct: 389 GEGTFGKV----VQCKDLLKGDDIALKIIKNV---DKYREAAKLEINVLEKLREKDPHAK 547
Query: 409 --IVRMIG-------ICEAESWMLVMEMAELGPLNKY----LQQNRHVKDKNIIELVHQV 455
V+M+ +C + ML + + + N Y ++Q RH+ +Q+
Sbjct: 548 HMCVQMLDWFDYHGHVCISFH-MLGLSVFDFLKDNSYGAYPIEQVRHIS--------YQL 700
Query: 456 SMGMKYLEESNFVHRDLAARNVLLVTQHYAKI 487
+ +L E+ H DL N+L V Y +
Sbjct: 701 CYAVNFLHENQLTHTDLKPENILFVDSQYENV 796
>18401
Length = 463
Score = 32.0 bits (71), Expect = 0.77, Method: Compositional matrix adjust.
Identities = 17/48 (35%), Positives = 26/48 (54%)
Frame = -3
Query: 517 APECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEK 564
APE I +S DVWS G +M+E ++ G ++ E AM+E+
Sbjct: 428 APEVILELGWSHPCDVWSVGCIMFELYT-GYTLFQTHDNKEHLAMMER 288
>00191
Length = 1400
Score = 31.6 bits (70), Expect = 1.00, Method: Compositional matrix adjust.
Identities = 16/39 (41%), Positives = 21/39 (53%)
Frame = -1
Query: 346 LLTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKNE 384
L L D LG NF K G+ +KKV+KT+ KN+
Sbjct: 1130 LXCLADPCLGVRNFRDTKSGFPPLKKVMKTITKPYXKNK 1014
>29590
Length = 320
Score = 31.2 bits (69), Expect = 1.3, Method: Composition-based stats.
Identities = 14/46 (30%), Positives = 26/46 (56%)
Frame = +3
Query: 515 WYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTA 560
+ APE ++Y S ++D+WS GVL + + P+ G+ + +A
Sbjct: 72 YVAPEVLDYEPLSIQTDMWSLGVLSYVMLT-ACSPFVGITSKKHSA 206
>25019
Length = 730
Score = 30.4 bits (67), Expect = 1.9, Method: Compositional matrix adjust.
Identities = 20/68 (29%), Positives = 28/68 (41%), Gaps = 4/68 (5%)
Frame = +3
Query: 473 AARNVLLVTQHYAKISDFGLSK----ALRADENYYKAQTHGKWPVKWYAPECINYYKFSS 528
AA NVLL + K++DFGL K R + +++ APE +
Sbjct: 255 AAENVLLDKDGHVKLTDFGLCKEAITGTRVTHTFCGT-------IEYMAPEILTRTGHGK 413
Query: 529 KSDVWSFG 536
D WS G
Sbjct: 414 AVDWWSLG 437
>02638
Length = 1490
Score = 30.4 bits (67), Expect = 2.3, Method: Compositional matrix adjust.
Identities = 26/97 (26%), Positives = 39/97 (40%), Gaps = 4/97 (4%)
Frame = +1
Query: 503 YKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAML 562
++ Q G + + APE + + DVWS G +M E + + P+ S A++
Sbjct: 4 FQGQLLGT--IAFMAPEVLRGESYGRACDVWSVGCVMIEMCTC-RPPWNSHDISNHLALI 174
Query: 563 EKGERMGCPAGCPREMY----DLMNLCWTYDVENRPG 595
K P P M DLM C D + RP
Sbjct: 175 FKIASSVDPPPIPENMSPPVRDLMLRCLEQDSDFRPS 285
>37602
Length = 804
Score = 30.0 bits (66), Expect = 2.6, Method: Compositional matrix adjust.
Identities = 17/72 (23%), Positives = 30/72 (41%)
Frame = -1
Query: 419 ESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVL 478
E + ME G + + + I + + G+ YL +HRD+ N+L
Sbjct: 300 EKLWIAMEYCGGGSMQDIYHVTGPLTEPQIAFVCRETLKGLHYLHRRGKMHRDIKGANIL 121
Query: 479 LVTQHYAKISDF 490
L + K++DF
Sbjct: 120 LTEEGDVKLADF 85
>07933
Length = 728
Score = 29.6 bits (65), Expect = 3.8, Method: Compositional matrix adjust.
Identities = 11/30 (36%), Positives = 17/30 (56%)
Frame = +3
Query: 571 PAGCPREMYDLMNLCWTYDVENRPGFAAVE 600
P CP +Y++M CW+ + RP F +E
Sbjct: 3 PNYCPNLLYNIMMQCWSAEPSARPTFHKLE 92
>14799
Length = 565
Score = 29.6 bits (65), Expect = 4.0, Method: Composition-based stats.
Identities = 17/43 (39%), Positives = 21/43 (48%)
Frame = -3
Query: 346 LLTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDP 388
L L D LG NF K G+ +KKV+KT+ K N P
Sbjct: 302 LRCLADPCLGVRNFRDTKSGFPPLKKVMKTITKPYNKKXKNRP 174
>30740
Length = 488
Score = 28.5 bits (62), Expect = 9.1, Method: Composition-based stats.
Identities = 21/74 (28%), Positives = 38/74 (51%), Gaps = 3/74 (4%)
Frame = +2
Query: 203 YALCLLHEGKVLHYRIDKDKTGKLSIPE--GKKFDTLWQLVEHY-SYKADGLLRVLTVPC 259
+ LC+ + KV HY I++ + G L+ + K+F+ + L+ Y S+ D + P
Sbjct: 5 FVLCVKEDSKVSHYIINRIQVGGLTRFKIGDKEFNDIPSLLNFYKSHYLDTTTLIRPAPR 184
Query: 260 QKIGTQGNVNFGGR 273
+K+ G +F GR
Sbjct: 185 EKL--MGKYDFSGR 220
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000364904 | hsapiens_gene_ensembl |
Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase).
[Source:Uniprot/SWISSPROT;Acc:P43405]
(612 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
06405 217 9e-57
11780 152 1e-56
21808 194 1e-49
14477 182 3e-46
09007 173 2e-43
04852 139 4e-33
07291 129 3e-30
14116 129 5e-30
20640 125 4e-29
17300 115 9e-27
07940 117 2e-26
22005 93 1e-24
18996 103 2e-22
08294 97 1e-20
17637 84 2e-16
18921 82 7e-16
01707 80 3e-15
00715 79 7e-15
13305 79 8e-15
17253 77 3e-14
01718 75 8e-14
13066 69 8e-12
19301 67 2e-11
01756 66 4e-11
12721 66 4e-11
14420 65 6e-11
09606 64 1e-10
21079 63 4e-10
18484 62 9e-10
00300 61 1e-09
01060 61 1e-09
14126 60 2e-09
13212 60 3e-09
31885 58 9e-09
19094 57 3e-08
04591 56 5e-08
29581 55 6e-08
12672 54 1e-07
17806 54 2e-07
27546 50 2e-06
25550 49 2e-06
19761 50 4e-06
07833 50 4e-06
26560 49 6e-06
30755 49 7e-06
27405 47 2e-05
03240 47 3e-05
01966 47 3e-05
15910 46 5e-05
07836 46 5e-05
26711 46 5e-05
28157 45 7e-05
04138 45 1e-04
01392 44 2e-04
11228 43 4e-04
12786 42 6e-04
11185 42 8e-04
10546 41 0.001
30231 40 0.003
13840 39 0.007
21433 38 0.010
04627 38 0.013
35671 38 0.014
00394 37 0.022
18881 36 0.038
18481 36 0.048
31489 35 0.064
31789 35 0.10
14257 34 0.20
26009 33 0.24
16708 33 0.35
38046 33 0.39
21210 32 0.52
15741 32 0.56
36481 32 0.60
18401 32 0.77
00191 32 1.00
29590 31 1.3
25019 30 1.9
02638 30 2.3
37602 30 2.6
07933 30 3.8
14799 30 4.0
30740 28 9.1
>06405
Length = 1965
Score = 217 bits (553), Expect = 9e-57, Method: Compositional matrix adjust.
Identities = 136/412 (33%), Positives = 212/412 (51%), Gaps = 5/412 (1%)
Frame = +1
Query: 201 GSYALCLLHEGKVLHYRIDKDKTGKLSIPEGKKFDTLWQLVEHYSYKADGLLRVLTVPCQ 260
G ++ + EG+V HYRI +D GK+ + + +F+TL +LV H+S ADGL+ L P
Sbjct: 19 GQRSISVRFEGRVYHYRITEDD-GKVFVTQEHRFNTLAELVHHHSIHADGLVTTLLYPAP 195
Query: 261 KIGTQGNVNFGGRPQLPGSHPASSPAQGNRQESTVSFNPYEPELAPWAADKGPQREALPM 320
K RQ+ TV
Sbjct: 196 K----------------------------RQKPTV------------------------- 216
Query: 321 DTEVYESPYADPEEIRPKEVYLDRKLLTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKI 380
SP D EI E+ + +L G G +G V + + K+ K VAVK
Sbjct: 217 ---FGVSPEPDRWEIERTEIAMKHRL--------GGGQYGDVYEAMW--KRYNKIVAVKT 357
Query: 381 LKNEANDPALKDELLAEANVMQQLDNPYIVRMIGICEAES-WMLVMEMAELGPLNKYLQQ 439
LK + AL D L EA +M+++ +P +V+++G+C E + +V E G L YL+
Sbjct: 358 LKEDTM--ALND-FLEEAAIMKEMKHPNLVQLLGVCTREPPFYIVTEFMPHGNLLDYLRS 528
Query: 440 NRHVKDKN----IIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKA 495
+ +++N ++ + Q++ GM YLE NF+HRDLAARN L+ + K++DFGL++
Sbjct: 529 S--TREENGPTALMYMATQIASGMAYLETKNFIHRDLAARNCLVADSNMVKVADFGLARL 702
Query: 496 LRADENYYKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKG 555
++ D Y A K+P+KW APE + + +FS++SD+W+FGVL+WE +YG PY G++
Sbjct: 703 MKDDT--YTAHIGAKFPIKWTAPEGLAFNRFSTRSDIWAFGVLLWELATYGMSPYPGVEL 876
Query: 556 SEVTAMLEKGERMGCPAGCPREMYDLMNLCWTYDVENRPGFAAVELRLRNYY 607
+EV +LE+G RM P G P ++Y LM CW +D ++RP F + L N +
Sbjct: 877 TEVYHLLERGYRMERPPGTPADVYILMLKCWQWDPKDRPTFKEIHFLLENMF 1032
Score = 31.6 bits (70), Expect = 0.86, Method: Compositional matrix adjust.
Identities = 25/84 (29%), Positives = 40/84 (47%), Gaps = 5/84 (5%)
Frame = +1
Query: 43 QSRNYLGGFALSVAHGRKAHHYTIERELNGTYAIAGGRTHASPADLCHYHSQESDGLVCL 102
+S + G ++SV + +HY I E +G + + A+L H+HS +DGLV
Sbjct: 1 ESESSPGQRSISVRFEGRVYHYRIT-EDDGKVFVTQEHRFNTLAELVHHHSIHADGLVTT 177
Query: 103 LKKPFNRPQ-----GVQPKTGPFE 121
L P + Q GV P+ +E
Sbjct: 178 LLYPAPKRQKPTVFGVSPEPDRWE 249
>11780
Length = 1713
Score = 152 bits (384), Expect(2) = 1e-56, Method: Compositional matrix adjust.
Identities = 122/359 (33%), Positives = 166/359 (46%), Gaps = 3/359 (0%)
Frame = +3
Query: 166 MPWFHGKISREESEQIVLIGSKTNGKFLIRARDNN-GSYALCLLHEGKVLHYRIDKDKTG 224
MPWFHGKI+R+++E+ L+ + +G FLIR N G Y LC+ H GKV HYRI +
Sbjct: 249 MPWFHGKITRQQAEE--LLKPREDGLFLIRESSNYPGDYTLCVCHLGKVEHYRILY-REN 419
Query: 225 KLSIPEGKKFDTLWQLVEHYSYKADGLLRVLTVPCQKIGTQGNVNFGGRPQLPGSHPASS 284
+L+I E F L +LV+HY ADGL LT P K G NFG
Sbjct: 420 QLTIDEEGFFRNLDELVKHYLADADGLCTQLTRPVTKQGG----NFG------------- 548
Query: 285 PAQGNRQESTVSFNPYEPELAPWAADKGPQREALPMDTEVYESPYADPEEIRPKEVYLDR 344
TVS ++ W D E+ E+
Sbjct: 549 ---------TVSLQEFKS--GGWVI--------AXQDLEIGEA----------------- 620
Query: 345 KLLTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQL 404
+G G+FG V KG Y+ + VA+K LK++ + L EA+VM L
Sbjct: 621 ---------IGKGDFGDVYKGMYRGQ----PVAIKQLKDKDRG---EQSFLQEASVMTSL 752
Query: 405 DNPYIVRMIGICEAESWMLVMEMAELGPLNKYLQQNRH--VKDKNIIELVHQVSMGMKYL 462
+ +VR+IG+ E+ LV E G L +YL+ + K+ I M+YL
Sbjct: 753 RHDNLVRLIGVVLGETIFLVTEFMGKGNLVEYLRSRGRSVITKKDQINFATDTCAAMEYL 932
Query: 463 EESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECI 521
E VHRDLAARNVL+ AK+SDFGL+K +QT K+P+KW APE +
Sbjct: 933 ESKRLVHRDLAARNVLVHDDGKAKVSDFGLAKFGDF------SQTSVKFPIKWTAPEAL 1091
Score = 87.0 bits (214), Expect(2) = 1e-56, Method: Compositional matrix adjust.
Identities = 38/81 (46%), Positives = 53/81 (65%)
Frame = +1
Query: 525 KFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAGCPREMYDLMNL 584
KF+SKSD+WSFG+L+WE +S+G+ PY + ++V +E+G RM P GCP E+Y +M
Sbjct: 1102 KFTSKSDMWSFGILLWEIYSFGRVPYPRIPLTDVVMHVERGYRMEAPEGCPPEIYSIMKQ 1281
Query: 585 CWTYDVENRPGFAAVELRLRN 605
W D RP F +V RL N
Sbjct: 1282 AWELDPNERPTFKSVLARLNN 1344
Score = 53.5 bits (127), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 43/133 (32%), Positives = 65/133 (48%), Gaps = 1/133 (0%)
Frame = +3
Query: 13 LPFFFGNITREEAEDYLVQGGMSDGLYLLRQSRNYLGGFALSVAHGRKAHHYTI-ERELN 71
+P+F G ITR++AE+ L DGL+L+R+S NY G + L V H K HY I RE
Sbjct: 249 MPWFHGKITRQQAEELLKP--REDGLFLIRESSNYPGDYTLCVCHLGKVEHYRILYRENQ 422
Query: 72 GTYAIAGGRTHASPADLCHYHSQESDGLVCLLKKPFNRPQGVQPKTGPFEDLKENLIREY 131
T G + +L ++ ++DGL L +P V + G F + ++E+
Sbjct: 423 LTIDEEG--FFRNLDELVKHYLADADGLCTQLTRP------VTKQGGNFGTVS---LQEF 569
Query: 132 VKQTWNLQGQALE 144
W + Q LE
Sbjct: 570 KSGGWVIAXQDLE 608
>21808
Length = 1011
Score = 194 bits (492), Expect = 1e-49, Method: Compositional matrix adjust.
Identities = 92/221 (41%), Positives = 146/221 (66%), Gaps = 2/221 (0%)
Frame = +1
Query: 376 VAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRMIGIC-EAESWMLVMEMAELGPLN 434
VA+K LK+ DP + LAEA +M++L +P ++++ +C + + ++ E+ + G L
Sbjct: 28 VAIKTLKSGTMDP---KDFLAEAQIMKKLRHPKLIQLYAVCTQDDPIFIITELMKNGSLL 198
Query: 435 KYLQ-QNRHVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLS 493
++LQ + R +K +I++ Q++ GM YLE N++HRDLAARN+L+ + KI+DFGL+
Sbjct: 199 EFLQGKGRVLKLPALIDIGAQIACGMAYLESQNYIHRDLAARNILVSDNNTVKIADFGLA 378
Query: 494 KALRADENYYKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGM 553
+ ++ DE Y+A+ ++P+KW APE NY +F+ KSDVWSFG+L+ E +YG+ PY GM
Sbjct: 379 RVIKEDE--YEARVGARFPIKWTAPEAANYNRFTIKSDVWSFGILLTETVTYGRVPYPGM 552
Query: 554 KGSEVTAMLEKGERMGCPAGCPREMYDLMNLCWTYDVENRP 594
+EV +E G RM CP GCP+ +YD+M CW + RP
Sbjct: 553 TNAEVLHQVEHGYRMPCPPGCPKPLYDIMLECWRKEEMERP 675
>14477
Length = 493
Score = 182 bits (462), Expect = 3e-46, Method: Compositional matrix adjust.
Identities = 86/160 (53%), Positives = 125/160 (78%)
Frame = -1
Query: 347 LTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQLDN 406
+ +++ +LG+GNFG+V KG ++ VA+K+LKN DP+++ EL+ EA VM+++D+
Sbjct: 487 IQMDELKLGAGNFGSVMKGVCRLDDREIPVAIKVLKNADLDPSVQSELIKEAEVMKKMDH 308
Query: 407 PYIVRMIGICEAESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSMGMKYLEESN 466
+IVR+IG+CE E+ MLV+E+A+LGPLNK+L +N+H+ NI+EL+ QVS GM+YLE +
Sbjct: 307 MHIVRLIGLCEGETMMLVLELAKLGPLNKFLPKNKHLPLWNILELMWQVSQGMEYLEANK 128
Query: 467 FVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQ 506
FVHRDLAARN+LL +H+AKISDFG+SK L + NYY AQ
Sbjct: 127 FVHRDLAARNILLCDEHFAKISDFGMSKTLSRENNYYMAQ 8
>09007
Length = 1440
Score = 173 bits (438), Expect = 2e-43, Method: Compositional matrix adjust.
Identities = 102/265 (38%), Positives = 150/265 (56%), Gaps = 13/265 (4%)
Frame = -1
Query: 352 KELGSGNFGTVKKGYYQMKKVVKT-VAVKILKNEANDPALKD--ELLAEANVMQQLDNPY 408
K LG G+FGTV++ + + K VAVK L + D KD E L E +MQ LD+
Sbjct: 861 KSLGQGHFGTVRQAIWTAESGEKVQVAVKCL---SKDKIHKDGQEFLKETAIMQMLDHEN 691
Query: 409 IVRMIGICEAESWMLVMEMAELGPLNKYLQQNRHVKDK------NIIELVHQVSMGMKYL 462
IVR+ G+ ++ +M + EL P+ L+ + V + + + QV GM YL
Sbjct: 690 IVRVYGVV-MDNGADIMLVTELAPMRSLLECVKEVSARVDFSVPRLCDFSQQVCDGMSYL 514
Query: 463 EESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQ--THGKWPVKWYAPEC 520
E VHRDLAARN+LL ++ KISD G+S AL A + YY++Q H + V W APE
Sbjct: 513 ESKRLVHRDLAARNILLFSKSKVKISDVGVSGALGAGKEYYQSQQTIHLQNAVAWCAPES 334
Query: 521 INYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLE--KGERMGCPAGCPREM 578
FSS SDVW+FGVL+WE F++G +P+ G+ G ++ ++ + +R+ P CP+E
Sbjct: 333 FRNLCFSSASDVWAFGVLLWEFFTHGFQPWAGLNGQQIMEAVDAPQSQRLEQPDLCPKEY 154
Query: 579 YDLMNLCWTYDVENRPGFAAVELRL 603
Y +M CW + + RP F+ + L L
Sbjct: 153 YAVMLKCWEQEPQRRPTFSQLFLTL 79
>04852
Length = 1462
Score = 139 bits (349), Expect = 4e-33, Method: Compositional matrix adjust.
Identities = 85/255 (33%), Positives = 132/255 (51%), Gaps = 32/255 (12%)
Frame = +1
Query: 375 TVAVKILKNEANDPALKDELLAEANVMQQL----DNPYIVRMIGICE--AESWMLVMEMA 428
TVAVK+L++ +D + E VM+ + + IV +G C W++V E A
Sbjct: 25 TVAVKMLRDIVTAVEEQD-FVQELQVMKAVKKMGSHINIVNFLGCCTQGGPLWVIV-EFA 198
Query: 429 ELGPLNKYLQQNRH-------------------------VKDKNIIELVHQVSMGMKYLE 463
+ G L +L+ R ++ KN++ Q++ GM++L
Sbjct: 199 KNGNLRDFLESCRDGINGYGKFVSPQDPGWYTKTPGGHVIRRKNLLSYAFQIARGMEFLA 378
Query: 464 ESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINY 523
+HRDLAARNVL+ +H KI+DFGLS+ +YYK ++ G+ PVKW APE +
Sbjct: 379 SRKCIHRDLAARNVLVTEEHVLKIADFGLSRT----GDYYKKRSGGRLPVKWMAPEALFD 546
Query: 524 YKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEV-TAMLEKGERMGCPAGCPREMYDLM 582
++++KSDVWSFGV++WE FS G PY + E+ + +L+ RM P +Y +M
Sbjct: 547 MRYTTKSDVWSFGVVLWEIFSLGGMPYASIPNEELYSKLLDDAYRMPRPELASGNLYAIM 726
Query: 583 NLCWTYDVENRPGFA 597
CW +RP F+
Sbjct: 727 ERCWLNRPSDRPEFS 771
>07291
Length = 833
Score = 129 bits (324), Expect = 3e-30, Method: Compositional matrix adjust.
Identities = 59/159 (37%), Positives = 94/159 (59%)
Frame = +1
Query: 448 IIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQT 507
+++ Q++ GM YL+E VHR+LAARN ++ ++SD+G++ +L Y +
Sbjct: 55 LLDFGRQIADGMAYLQEVKVVHRNLAARNCIVTEDGRLQLSDYGVTGSLFPQSYYTADDS 234
Query: 508 HGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGER 567
+ VKW APE I+ + FSSKSDVW+FGV++WE + G PY ++ S + L++G R
Sbjct: 235 PARDLVKWMAPETIDNFHFSSKSDVWAFGVVLWELLTRGITPYPDVENSSLLPYLKEGHR 414
Query: 568 MGCPAGCPREMYDLMNLCWTYDVENRPGFAAVELRLRNY 606
M P P +Y++M CW E RP FA + +L+ +
Sbjct: 415 MKKPKQSPEPVYEMMTACWNESPEQRPDFAELNDQLKTF 531
>14116
Length = 1017
Score = 129 bits (323), Expect = 5e-30, Method: Compositional matrix adjust.
Identities = 77/217 (35%), Positives = 119/217 (54%), Gaps = 5/217 (2%)
Frame = -1
Query: 335 IRPKEVYLDRKLLTLEDKELGSGNFGTVKKGYYQM--KKVVKTVAVKILKNEANDPALKD 392
I + + +DR+ LT+ +E+G GNFG VK+G+ + +K VAVK L N
Sbjct: 666 IENESLLIDREFLTM-GEEIGKGNFGCVKRGFLTLPEQKGDILVAVKTLHNNNPREIELQ 490
Query: 393 ELLAEANVMQQLDNPYIVRMIGICEAESWM--LVMEMAELGPLNKYLQQNRHVKD-KNII 449
L EA +M+ + ++ +IGIC M +V+ + G L Y++ ++H K++I
Sbjct: 489 SFLQEALIMKDFHHSNVLTLIGICLNLDDMPLVVLPFMKHGDLLTYIRDDQHQPTIKDLI 310
Query: 450 ELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHG 509
++ GM YL FVHRDLAARN +L + K++DFGL++ + E Y
Sbjct: 309 MYGVDIARGMDYLAGLKFVHRDLAARNCMLDEDFHVKVADFGLARDIYEKEYYSSENKKA 130
Query: 510 KWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYG 546
K PVKW A E + + SK+DVWS+GV++WE + G
Sbjct: 129 KLPVKWMALESLEKGNYDSKTDVWSYGVVLWELLTRG 19
>20640
Length = 1492
Score = 125 bits (315), Expect = 4e-29, Method: Compositional matrix adjust.
Identities = 58/139 (41%), Positives = 84/139 (60%)
Frame = +1
Query: 467 FVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINYYKF 526
+VHRDLA RN L+ KISDFGL++++ + +YY+ H P++W E I Y KF
Sbjct: 7 YVHRDLATRNCLVGHDLVVKISDFGLARSVHS-VDYYRGSEHDAIPIRWMPLEAILYNKF 183
Query: 527 SSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAGCPREMYDLMNLCW 586
S++SDVWSFGV++WE F++ +PY G+ EV +++G+ + CP P MY+LM CW
Sbjct: 184 STQSDVWSFGVVLWEIFAFALQPYYGLTHEEVVRFVKEGKVLACPERTPPPMYELMKQCW 363
Query: 587 TYDVENRPGFAAVELRLRN 605
RP F + L N
Sbjct: 364 HRRPATRPSFHTLHKTLEN 420
>17300
Length = 480
Score = 115 bits (287), Expect(2) = 9e-27, Method: Compositional matrix adjust.
Identities = 57/116 (49%), Positives = 76/116 (65%), Gaps = 2/116 (1%)
Frame = +1
Query: 455 VSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRAD--ENYYKAQTHGKWP 512
+S GM L + +VHRDLAARN+L+ K++DFGLS+ + +D E Y + GK P
Sbjct: 1 ISSGMGXLADMGYVHRDLAARNILVNEILVCKVADFGLSREIESDTTEGAYTTK-GGKIP 177
Query: 513 VKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERM 568
V+W APE I Y KF+S SDVWSFGV+MWE SYG++PY +V +EKG R+
Sbjct: 178 VRWTAPEAIAYRKFTSASDVWSFGVVMWEVMSYGERPYWNWSNQDVIKAVEKGYRL 345
Score = 23.9 bits (50), Expect(2) = 9e-27, Method: Composition-based stats.
Identities = 10/32 (31%), Positives = 16/32 (50%), Gaps = 1/32 (3%)
Frame = +2
Query: 569 GCPA-GCPREMYDLMNLCWTYDVENRPGFAAV 599
CP+ CP ++ LM W + +RP + V
Sbjct: 341 ACPSMDCPEALHQLMLDAWQKERSHRPKMSMV 436
>07940
Length = 1336
Score = 117 bits (292), Expect = 2e-26, Method: Compositional matrix adjust.
Identities = 53/105 (50%), Positives = 75/105 (71%)
Frame = -3
Query: 446 KNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKA 505
K++I +QV+ GM+YL +HRDLAARNVL+ ++ KI+DFGL++ L+ +YY+
Sbjct: 347 KDLISYAYQVARGMEYLASKQCIHRDLAARNVLVAEEYVLKIADFGLTRNLQ-QFDYYRK 171
Query: 506 QTHGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPY 550
T G+ PVKW APE + K++SKSDVWS+GVL+WE F+ G PY
Sbjct: 170 TTDGRLPVKWMAPEALFDRKYTSKSDVWSYGVLLWEIFTLGGNPY 36
>22005
Length = 873
Score = 93.2 bits (230), Expect(2) = 1e-24, Method: Compositional matrix adjust.
Identities = 74/244 (30%), Positives = 118/244 (48%), Gaps = 54/244 (22%)
Frame = +1
Query: 352 KELGSGNFGTVKK-GYYQMKKVVKTVAV--------KILKNEANDPALKDELLAEANVMQ 402
+++G G FG V K + + +V + K+LK +A++ L+ + EA++M
Sbjct: 1 RDIGQGAFGRVSKLKFLGLASLVGELIPEKRP*LL*KMLKEDASED-LQSDFEREASLMA 177
Query: 403 QLDNPYIVRMIGICEAESWM-LVMEMAELGPLNKYLQ--------------QNRHV---- 443
D+P IV+++G+C M L+ E G LN +L+ QN V
Sbjct: 178 DFDHPNIVKLLGVCAIGKPMCLLFEFMSKGDLNDFLRLCSPENYNLPVSRSQNLVVDLED 357
Query: 444 ------------KD--------------KNIIELVHQVSMGMKYLEESNFVHRDLAARNV 477
KD K+ + + Q+S GM YL + ++VHRDLA R V
Sbjct: 358 GLRVEVEAEECEKDTQSEDRDCSGMLXTKDQLYISQQISAGMAYLAQKDYVHRDLATRTV 537
Query: 478 LLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFGV 537
+ ISDFGL++++ + +YY+ P++W E I Y KFS++SDVWSFGV
Sbjct: 538 X-SRTT*S*ISDFGLARSVHS-VDYYRGSEQDAIPIRWMPLEAILYSKFSTQSDVWSFGV 711
Query: 538 LMWE 541
++WE
Sbjct: 712 VLWE 723
Score = 38.5 bits (88), Expect(2) = 1e-24, Method: Compositional matrix adjust.
Identities = 16/53 (30%), Positives = 28/53 (52%)
Frame = +3
Query: 543 FSYGQKPYRGMKGSEVTAMLEKGERMGCPAGCPREMYDLMNLCWTYDVENRPG 595
F++ +PY G+ EV ++ G+ + P P ++Y+LM CW + RP
Sbjct: 726 FAFALQPYYGLTHEEVVNYVKAGKILEQPTKTPHQVYELMKQCW----QRRPA 872
>18996
Length = 491
Score = 103 bits (257), Expect = 2e-22, Method: Compositional matrix adjust.
Identities = 60/137 (43%), Positives = 79/137 (57%), Gaps = 5/137 (3%)
Frame = +2
Query: 468 VHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINYYKFS 527
+HRDLAARN+L V + KISDFGL++ AD YY + P+KWY+PE I KFS
Sbjct: 2 IHRDLAARNIL-VDRSCVKISDFGLAQFANAD-GYYYGISQRDIPIKWYSPEAIETCKFS 175
Query: 528 SKSDVWSFGVLMWEAFSYGQKPY----RGMKGSEVTAMLEKGERMGCPAGCPREMY-DLM 582
S SDVWS+GV ++E FS G+ P + E L KGER+ P C +Y +LM
Sbjct: 176 SYSDVWSYGVTLFEMFSRGEIPNLLPGHDLTQEEFLNRLRKGERLPKPELCSDFVYSELM 355
Query: 583 NLCWTYDVENRPGFAAV 599
CW ++RP F +
Sbjct: 356 RPCWHEMPKSRPTFHQI 406
>08294
Length = 1849
Score = 97.4 bits (241), Expect = 1e-20, Method: Compositional matrix adjust.
Identities = 66/218 (30%), Positives = 96/218 (44%), Gaps = 13/218 (5%)
Frame = +2
Query: 407 PYIVRMIGIC-EAESWMLVMEMAELGPLNKYLQQNRHVKDK------------NIIELVH 453
P IV +G+C EAE L+ E + G L ++L R+ + + +
Sbjct: 887 PNIVHFMGVCREAEPHFLITEYCDWGDLKQFLLATRNDNGRGRGTRVPALALSQKLGMGQ 1066
Query: 454 QVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPV 513
QV+ GM+ L VH DLAARNVLL ++ K++ LS + A E Y Q P+
Sbjct: 1067 QVAAGMEALSNQGLVHGDLAARNVLLTSRMQLKVARPALSGDVYASEYYPLHQR--LVPL 1240
Query: 514 KWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAG 573
+W PE + ++ DVW+FGV +WE PYR M EV L+ +
Sbjct: 1241 RWLPPEGVLEDSATTCGDVWAFGVFLWEVLQLADLPYRLMSDEEVLRSLQHSQAALDSPD 1420
Query: 574 CPREMYDLMNLCWTYDVENRPGFAAVELRLRNYYYDVV 611
P + L+ C RP F+ + L DVV
Sbjct: 1421 APPALLSLLQRCTAQQPSQRPPFSEICSVLSLASTDVV 1534
>17637
Length = 447
Score = 84.0 bits (206), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 43/137 (31%), Positives = 73/137 (53%), Gaps = 1/137 (0%)
Frame = +1
Query: 476 NVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKW-PVKWYAPECINYYKFSSKSDVWS 534
N ++ Q K++D LS+ L + + Y G++ P+KW + E + ++ SDVWS
Sbjct: 1 NCVIDDQLRVKLTDSALSRDLFSGD--YNCLGDGEYRPIKWLSLEALQKSHYNEGSDVWS 174
Query: 535 FGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAGCPREMYDLMNLCWTYDVENRP 594
FGVLMWE + G+ PY + E+ L+ G R+ P CP E++ +M CW RP
Sbjct: 175 FGVLMWEMCTLGKLPYAEIDPYEMEHYLKDGYRLAQPFNCPDELFTIMAYCWASMPAERP 354
Query: 595 GFAAVELRLRNYYYDVV 611
F+ +++ L ++ +
Sbjct: 355 SFSQLQICLSEFHTQIT 405
>18921
Length = 697
Score = 82.0 bits (201), Expect = 7e-16, Method: Compositional matrix adjust.
Identities = 57/192 (29%), Positives = 101/192 (52%), Gaps = 3/192 (1%)
Frame = +2
Query: 353 ELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRM 412
+LG G++G+V K ++ +T V +K D L+ E++ E ++MQQ D+ YIV+
Sbjct: 50 KLGEGSYGSVFKSLHK-----ETGQVLAIKQVPVDTDLQ-EIIKEISIMQQCDSKYIVKY 211
Query: 413 IG--ICEAESWMLVMEMAELGPLNKYLQ-QNRHVKDKNIIELVHQVSMGMKYLEESNFVH 469
G + W +VME G ++ ++ +N+ + ++ I +++ G+ YL +H
Sbjct: 212 YGSYFKNTDLW-IVMEYCGAGSVSDIMRLRNKTLVEREIATILYYTLKGLXYLHSRRKIH 388
Query: 470 RDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINYYKFSSK 529
RD+ A N+LL + +AK++DFG++ L + K T P W APE I +
Sbjct: 389 RDIKAGNILLNNEGHAKLADFGVAGQLT--DTMAKRNTVIGTPY-WMAPEVIQEIGYDCV 559
Query: 530 SDVWSFGVLMWE 541
+D+WS G+ E
Sbjct: 560 ADIWSLGITALE 595
>01707
Length = 757
Score = 80.1 bits (196), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 51/214 (23%), Positives = 105/214 (49%), Gaps = 2/214 (0%)
Frame = +1
Query: 353 ELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRM 412
++G G++G V K + K+ + VA+K +DP +K + E +++QL +P +VR+
Sbjct: 85 KIGEGSYGVVFKC--RNKETSQLVAIKKFVESEDDPLIKKIAMREIRMLKQLKHPNLVRL 258
Query: 413 IGICEAESWM-LVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSMGMKYLEESNFVHRD 471
I + + + LV + + LN+ + R + + + +++Q + + + + N +HRD
Sbjct: 259 IEVFRRKKRLHLVFDYVDHTLLNELDRYPRGLPEPMVKRIIYQTLLAVNFCHQYNTIHRD 438
Query: 472 LAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPE-CINYYKFSSKS 530
+ N+L+ Q K+ DFG ++ L + Y +W + APE + ++
Sbjct: 439 VKPENILITRQGQVKLCDFGFARILTGPGDEYTDYVATRW---YRAPELLVGDTQYGPPV 609
Query: 531 DVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEK 564
DVW+ G + E + GQ + G + ++ K
Sbjct: 610 DVWAIGCVFAELLT-GQALWPGRSDVDQLHLIRK 708
>00715
Length = 1788
Score = 78.6 bits (192), Expect = 7e-15, Method: Compositional matrix adjust.
Identities = 73/259 (28%), Positives = 112/259 (43%), Gaps = 38/259 (14%)
Frame = +1
Query: 374 KTVAVKILKNEANDP-ALK----DELLAEANVMQQLDNPYIVRMIGIC-----EAESWML 423
+TVAVKI +++P AL+ +ELLA ++ ++ +V ++G E +W+
Sbjct: 1 RTVAVKIYHKRSSNPRALRQSYSNELLAFRCGLRHVN---VVSILGATSLHRFEDGAWL- 168
Query: 424 VMEMAELGPLNKYLQQNRHVKDKNI---IELVHQVSMGMKYLEESNFVHRDLAARNVLLV 480
M +GPLN N H +D + + L Q++ G+ YL N VH DL N LL
Sbjct: 169 --AMEYVGPLNLQTILNDHQQDIDSSMRLSLALQMARGLHYLHSINIVHLDLKPANCLLT 342
Query: 481 TQHYAKISDFGLSKALR-------------ADENYYKAQTHGKW------PVKWYAPECI 521
+I+DFG L A G W + + APE +
Sbjct: 343 RDLKLRIADFGCCHQLTPTGLDMGEREGGMAGNELELTPVQGAWKNELAGTLAYRAPELL 522
Query: 522 NYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAGC----PRE 577
+ S +SDV+S G+ +W+ + Q PY G+ V + + CP P E
Sbjct: 523 KGLQPSVRSDVYSLGITLWQMCTR-QGPYEGVPAHAVVYQVVSKDLRPCPPPSTEDDPFE 699
Query: 578 MY--DLMNLCWTYDVENRP 594
+ DL CW VE+RP
Sbjct: 700 VMFRDLYTQCWARRVEDRP 756
>13305
Length = 549
Score = 78.6 bits (192), Expect = 8e-15, Method: Composition-based stats.
Identities = 34/98 (34%), Positives = 54/98 (55%)
Frame = +2
Query: 512 PVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCP 571
P++W A E + ++++SDVWSFGV++WE F+ G PY ++ A L+ G R+ P
Sbjct: 14 PIRWMAVESLFNNTYTTQSDVWSFGVVLWEIFTLGGTPYSSTDTQQLFAFLKDGYRLKRP 193
Query: 572 AGCPREMYDLMNLCWTYDVENRPGFAAVELRLRNYYYD 609
C + Y +M CW + + RP F + RL+ D
Sbjct: 194 KLCDQNTYAMMLQCWNENAQRRPTFPELCGRLQRMLDD 307
>17253
Length = 483
Score = 76.6 bits (187), Expect = 3e-14, Method: Composition-based stats.
Identities = 48/155 (30%), Positives = 82/155 (52%), Gaps = 14/155 (9%)
Frame = -1
Query: 375 TVAVKILKNEANDPALKDELLAEANVMQQLD-NPYIVRMIGICE-AESWMLVMEMAELGP 432
TVAVK NEA A K E L E ++M++L +P +V +G C ++ +++ME G
Sbjct: 462 TVAVKT-HNEAATDAEKSEFLRELSIMRKLPRHPNVVSFMGCCTMSDPALILMEFCCHGD 286
Query: 433 LNKYLQQNR------------HVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLV 480
L +L++ R + ++ V+ GM ++ + VHRD+AARNVL+
Sbjct: 285 LLSFLRKRRPDRTVFLTSTANDLTARDFFSFALHVARGMAHVANNKIVHRDVAARNVLIS 106
Query: 481 TQHYAKISDFGLSKALRADENYYKAQTHGKWPVKW 515
++ K+SDFGLS+ + + Y+ + P++W
Sbjct: 105 ERNVCKVSDFGLSRRVGDQNDVYEIVSRRPLPLRW 1
>01718
Length = 959
Score = 75.1 bits (183), Expect = 8e-14, Method: Compositional matrix adjust.
Identities = 67/265 (25%), Positives = 128/265 (48%), Gaps = 16/265 (6%)
Frame = +3
Query: 352 KELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVR 411
+++G+G F V K +++ V +A+K+ +N + +L E ++ +L + I+R
Sbjct: 165 EKIGAGFFSEVFKVTHRITGQV--MALKMNTMTSN----RHNMLREVQLLNRLQHANILR 326
Query: 412 MIGICEAESWMLVM-EMAELGPLNKYLQQNRHVKDKNI-----IELVHQVSMGMKYLEES 465
+G+C E + + E G L + L++ KD+ + I+L ++ G+ YL +
Sbjct: 327 FMGVCVHEGQLHALTEYIPSGNLEQLLEK----KDEELPWTQRIQLTLGLARGLDYLHST 494
Query: 466 NFVHRDLAARNVLLVTQ----HYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECI 521
F+HRDL ++N+L+ + ++A I+DFGL+ + + K T G W APE +
Sbjct: 495 RFIHRDLTSKNILIRREDNHGYHAVIADFGLATKIPDPLDKEKLPTVGS--PYWMAPEVL 668
Query: 522 NYYKFSSKSDVWSFGVLMWEAFSY-----GQKPYRGMKGSEVTAMLEKGERMGCPAGCPR 576
N + ++ ++D++S G++M E + P G + A+ E + CP
Sbjct: 669 NGHFYNERADLFSVGIIMCEITARIPADPDIMPRMNNFGVDYVALSEM------ISYCPL 830
Query: 577 EMYDLMNLCWTYDVENRP-GFAAVE 600
+ L C D + RP G +E
Sbjct: 831 DYLQLAFKCCQVDPQKRPRGVEIIE 905
>13066
Length = 551
Score = 68.6 bits (166), Expect = 8e-12, Method: Compositional matrix adjust.
Identities = 52/182 (28%), Positives = 86/182 (47%), Gaps = 5/182 (2%)
Frame = +3
Query: 360 GTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLA-EANVMQQLDNPYIVRMIGICE- 417
GT GY + K+ A KI+ E ++ E +++ +LD+PYI+++ I +
Sbjct: 24 GTFNDGYGRNIKL----ACKIIDKEKAPVDFVEKFFPRELDLLTKLDHPYIIQIHSILQR 191
Query: 418 AESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNV 477
+ M AE G L Y+Q+ VK+K +Q++ + YL + HRDL N+
Sbjct: 192 XPKNFIFMRFAERGDLLTYIQEVGFVKEKQAKIWFYQMTTALNYLHSYDVAHRDLKCENI 371
Query: 478 LLVTQHYAKISDFGLSKAL--RADENYYKAQTHGKWPVKWYAPECINYYKFSSK-SDVWS 534
LL + K++DFG + A + E Y G + APE + ++ K +D WS
Sbjct: 372 LLSSHFNVKLADFGFACACITESGEKYMSRTYCGS--AAYAAPEIVYGAPYAPKVADAWS 545
Query: 535 FG 536
G
Sbjct: 546 LG 551
>19301
Length = 712
Score = 67.0 bits (162), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 43/143 (30%), Positives = 73/143 (51%), Gaps = 3/143 (2%)
Frame = +2
Query: 354 LGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANV--MQQLDNPYIVR 411
LGSG G V G K + VAVK +++ + E ++ +++L++P I+
Sbjct: 329 LGSGAQGAVFLG----KLCAEEVAVKKVRD-----------IKETDIRNLRKLNHPNIIS 463
Query: 412 MIGIC-EAESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSMGMKYLEESNFVHR 470
G+C +A + ++ME G L + L+ + + +++ Q++ GM YL +HR
Sbjct: 464 FKGVCTQAPCYCIIMEYCPYGQLYEVLRDGKEIPPALVLDWSKQIASGMNYLHSHKIIHR 643
Query: 471 DLAARNVLLVTQHYAKISDFGLS 493
DL + NVL+ KISDFG S
Sbjct: 644 DLKSPNVLVAKNDVVKISDFGTS 712
>01756
Length = 1858
Score = 66.2 bits (160), Expect = 4e-11, Method: Compositional matrix adjust.
Identities = 51/203 (25%), Positives = 91/203 (44%), Gaps = 11/203 (5%)
Frame = -3
Query: 353 ELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRM 412
++G G FG V K + KK + VA+K + + L E ++Q L++ +V +
Sbjct: 1721 KIGQGTFGEVFKA--RCKKTKQVVAMKKVLMDNEKEGFPITALREIKILQLLNHENVVDL 1548
Query: 413 IGICEAES---------WMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSMGMKYLE 463
I IC ++ + LV E E + I E++ Q+ G+ Y+
Sbjct: 1547 IEICSTKATSANRYKSMFYLVFEFCEHDLAGLLSNMSVVFNLPEIKEVMKQLMNGLYYIH 1368
Query: 464 ESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPE--CI 521
+ +HRD+ A N+L+ Q K++DFGL++A + T+ + WY P +
Sbjct: 1367 RNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTN-RVVTLWYRPPELLL 1191
Query: 522 NYYKFSSKSDVWSFGVLMWEAFS 544
+S+ D W G +M E ++
Sbjct: 1190 GDRNYSTAIDQWGAGCIMAEMWT 1122
>12721
Length = 821
Score = 66.2 bits (160), Expect = 4e-11, Method: Compositional matrix adjust.
Identities = 43/171 (25%), Positives = 76/171 (44%), Gaps = 7/171 (4%)
Frame = +1
Query: 391 KDELLAEANVMQQLDNPYIVRMIG--ICEAESWMLVMEMAELGPLNKYLQQNRHVKDKNI 448
++ L E VM+ +P IV M + E W +VME E G L + NR + + I
Sbjct: 208 RELLFNEVVVMRDYHHPNIVEMYNSYLVNDELW-VVMEFMEGGALTDIVTNNR-MDEVQI 381
Query: 449 IELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTH 508
+ + +L + +HRD+ + ++LL K+ DFG + D K+
Sbjct: 382 ATVCRACLKALAFLHANGVIHRDIKSDSILLSHDGKVKLXDFGFCAQVTQDLQKRKSLVG 561
Query: 509 GKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFS-----YGQKPYRGMK 554
+ W APE I+ + + D+WS G+++ E + + P + M+
Sbjct: 562 TPY---WMAPEVISRLPYGPEVDIWSLGIMVMEMIDAEPPFFNEPPLQAMR 705
>14420
Length = 528
Score = 65.5 bits (158), Expect = 6e-11, Method: Compositional matrix adjust.
Identities = 45/162 (27%), Positives = 78/162 (48%), Gaps = 2/162 (1%)
Frame = +2
Query: 391 KDELLAEANVMQQLDNPYIVRMIG--ICEAESWMLVMEMAELGPLNKYLQQNRHVKDKNI 448
K+ ++ E VM++ NP IV + + E W +VME G L + + + + I
Sbjct: 32 KELIINEILVMRENQNPNIVNYLDSYLVGEELW-VVMEFLAGGSLTDVVTET-CMDEGQI 205
Query: 449 IELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTH 508
+ + +++L E+ +HRD+ + N+LL K++DFG L +++ K T
Sbjct: 206 AAVCRECLQALEFLHENQVIHRDIKSDNILLGMDGSVKLTDFGFCAQLSPEQS--KRSTM 379
Query: 509 GKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPY 550
P W APE + ++ D+WS GV+ E G+ PY
Sbjct: 380 VGTP-YWMAPEVVTRKQYGPTVDIWSLGVMCIEMIE-GEPPY 499
>09606
Length = 1300
Score = 64.3 bits (155), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 55/221 (24%), Positives = 97/221 (43%), Gaps = 20/221 (9%)
Frame = -3
Query: 352 KELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVR 411
+ELG G + KG + K + VA+ ++ + E+ + + +P +V+
Sbjct: 1097 EELGKGEHSIIYKG--RRKGTINFVAIHCIEK-----CKRPEVTNTVRMTHDISHPNVVQ 939
Query: 412 MIGICEAESWM-LVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSMGMKYLEESNFVHR 470
E + + LV+E+ G L L Q+ H+ + +I + + G+ Y+ +
Sbjct: 938 FHEWYETSNHLWLVVELCTGGSLADILAQDHHLPETSIRDFGIHLVTGLHYIHSLGILFH 759
Query: 471 DLAARNVLLVTQHYAKISDFGLSKA--LRADENYYK-AQTHGKWPVK------------- 514
DL VLL T K +DFGLSK +E ++K A+ +W ++
Sbjct: 758 DLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQWNIQSAEEMMKQVPTSG 579
Query: 515 ---WYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRG 552
+ APE + S SD+W+ G + +E FS G P+ G
Sbjct: 578 SPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFS-GHPPFLG 459
>21079
Length = 878
Score = 62.8 bits (151), Expect = 4e-10, Method: Compositional matrix adjust.
Identities = 42/146 (28%), Positives = 75/146 (51%), Gaps = 3/146 (2%)
Frame = +1
Query: 420 SWMLVMEMAELGPL-NKYLQQNRHVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVL 478
+ +LVME G L + ++ + + +++ + V Q+ G+ Y+ + +H DL NVL
Sbjct: 46 TMVLVMEFVGAGELFERVIRDDFVLTERDCVHFVRQICSGVGYMHTQSILHLDLKPENVL 225
Query: 479 LVT--QHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFG 536
V+ + KI DFGL++ + ++ Q P ++ APE +NY + + +D+WS G
Sbjct: 226 CVSDNSNQIKIIDFGLARFYKPGDSL---QVLFGTP-EFIAPEVVNYDEINFTTDMWSIG 393
Query: 537 VLMWEAFSYGQKPYRGMKGSEVTAML 562
V+ + S G+ S VT ML
Sbjct: 394 VICYILLS-------GLSPSRVTTML 450
>18484
Length = 635
Score = 61.6 bits (148), Expect = 9e-10, Method: Compositional matrix adjust.
Identities = 41/150 (27%), Positives = 75/150 (50%), Gaps = 1/150 (0%)
Frame = +1
Query: 437 LQQNRHVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSK-A 495
+QQ K+ ++++G+ +L + ++RDL NV+L ++ + KI+DFG+ K
Sbjct: 16 IQQEGKFKEPVAAFYAAEIAVGLFFLHDQGIIYRDLKLDNVMLDSEGHIKIADFGMCKEG 195
Query: 496 LRADENYYKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKG 555
+ D +T P + APE + Y +S D W++GVL++E + GQ P+ G
Sbjct: 196 MTGDAT---TRTFCGTP-DYIAPEIVLYQPYSKSVDWWAYGVLLFEMLA-GQPPFDGEDE 360
Query: 556 SEVTAMLEKGERMGCPAGCPREMYDLMNLC 585
E+ + + + P RE ++LC
Sbjct: 361 DELFSSITD-HNVSYPKAMSREA---VSLC 438
>00300
Length = 2318
Score = 61.2 bits (147), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 48/246 (19%), Positives = 106/246 (43%), Gaps = 5/246 (2%)
Frame = -1
Query: 353 ELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRM 412
++G G FG V + +A+K +K + ND E+ E + + + + +V+
Sbjct: 1637 KIGEGQFGKVYTAVNM--STGELMALKEMKFQPNDLQQLREMCDEIKIFEGIQHENLVKY 1464
Query: 413 IGI-CEAESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSMGMKYLEESNFVHRD 471
G+ + ++ ME + G + + + + + I ++ + + +L E++ VHRD
Sbjct: 1463 YGVEVHKDEMLMFMEYCDTGTIEEAAKMG--LPEYLIRRYTREIVLAVNHLHENSIVHRD 1290
Query: 472 LAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINYYK---FSS 528
+ N+ L + + K+ DFG S L++ + + APE +
Sbjct: 1289 IKGANIFLTSNGHVKLGDFGCSVKLKSHTTMPGEFHNLVGTTAYMAPEVFTQNDQGGYGR 1110
Query: 529 KSDVWSFGVLMWEAFSYGQKPYRGMKGS-EVTAMLEKGERMGCPAGCPREMYDLMNLCWT 587
+D+WS G ++ E + G++P+ + + ++ + G + P E ++L
Sbjct: 1109 AADIWSLGCVVIE-MATGKRPWHDLDNNYQIMYKVGIGHKPAVPDSLSVEGKHFLDLIMC 933
Query: 588 YDVENR 593
+D R
Sbjct: 932 HDPAQR 915
>01060
Length = 1800
Score = 60.8 bits (146), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 48/192 (25%), Positives = 93/192 (48%), Gaps = 5/192 (2%)
Frame = +1
Query: 352 KELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVR 411
+++G G +G V K + + + +A+K ++ ++ + + E ++++L + IV
Sbjct: 91 QKIGEGTYGVVYKCRH--RATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTNIVC 264
Query: 412 MIG-ICEAESWMLVMEMAELGPLNKYLQQNRH--VKDKNIIE-LVHQVSMGMKYLEESNF 467
+ I E E LV E + L Y+ + V D+ +++ V Q+ G+ + +
Sbjct: 265 LEDVIMEDERLFLVFEFLSMD-LKMYIDKFPEGVVLDRRLVKSYVFQIVTGIXFCHQRRI 441
Query: 468 VHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECI-NYYKF 526
VHRDL +N+L+ KI+DFG+++ Y + W + APE + K+
Sbjct: 442 VHRDLKPQNLLINHTGAIKIADFGMARTFALPVRAYTHEVVTLW---YRAPEILMGASKY 612
Query: 527 SSKSDVWSFGVL 538
S+ DVWS G +
Sbjct: 613 STPVDVWSIGTI 648
>14126
Length = 1265
Score = 60.1 bits (144), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 51/202 (25%), Positives = 103/202 (50%), Gaps = 11/202 (5%)
Frame = +3
Query: 354 LGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQLD---NPYIV 410
+G+G +GTV K ++ + VA+K ++ + + + E ++++QL+ +P +V
Sbjct: 213 IGNGAYGTVYKAR-DLRNQGEFVAMKRIRLNNTEEGMPMMAIREISMLKQLEQYEHPNVV 389
Query: 411 RMIG-----ICEAESWM-LVMEMAELGPLNKYLQQ--NRHVKDKNIIELVHQVSMGMKYL 462
R++ I + E + LV E E L YL + + + I +L+ Q+ G+ +L
Sbjct: 390 RLLDVSHNTITDREIRLNLVFEYIE-HDLATYLAKCPSPGLGPDRIKDLMLQLLNGVDFL 566
Query: 463 EESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECIN 522
+ VHRDL +N+L+ K++DFGL++ +++ A T + + +PE +
Sbjct: 567 HSNRIVHRDLKPQNLLISKDGRLKLADFGLARIY----SFHMALTTVVVTLWYRSPEVLM 734
Query: 523 YYKFSSKSDVWSFGVLMWEAFS 544
++ + D+WS G + E F+
Sbjct: 735 QAEYGTSVDIWSCGCIFAELFT 800
>13212
Length = 1067
Score = 60.1 bits (144), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 45/160 (28%), Positives = 70/160 (43%), Gaps = 9/160 (5%)
Frame = -1
Query: 447 NIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQ 506
I + H++ M + +L + +HRD+ A NVLL K++DFG+S + + K
Sbjct: 977 QICYVCHEMCMALDFLHRHHVIHRDIKAGNVLLTIDGEVKLADFGVSA--KNTQTQQKRD 804
Query: 507 THGKWPVKWYAPECI-------NYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVT 559
T P W APE + Y F K+D+WS GV + E F+ + P + M V
Sbjct: 803 TFIGTPY-WMAPEVVLCETLKDTPYDF--KADIWSLGVTLIE-FAQIEPPNKEMHPMRVL 636
Query: 560 AMLEKGE--RMGCPAGCPREMYDLMNLCWTYDVENRPGFA 597
+ K + + P + D + C D RP A
Sbjct: 635 IKIHKSDPPTLEKPKKWTKLFKDFIAKCLVKDPNLRPTAA 516
>31885
Length = 529
Score = 58.2 bits (139), Expect = 9e-09, Method: Compositional matrix adjust.
Identities = 42/170 (24%), Positives = 82/170 (48%), Gaps = 6/170 (3%)
Frame = -2
Query: 398 ANVMQQLDNPYIVRM-IGICEAESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVS 456
+++ +LD+P++V + + E +V+++ G L ++QQ ++ + + Q++
Sbjct: 519 VDMLTRLDHPFLVNLWYAFQDEEDLFMVVDLFLGGDLRYHMQQEVSFREDCVKFYLCQLA 340
Query: 457 MGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWY 516
+ + YL VHRD+ N+LL Q + ++DF ++ L DE T G P +
Sbjct: 339 LVLDYLRSQKIVHRDIKPDNILLDEQGHCHVTDFNIATQLEDDE--LATSTSGTRP--YM 172
Query: 517 APEC----INYYK-FSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAM 561
APE IN + + D WS GV ++E ++P+ + + M
Sbjct: 171 APEVYGVAINERRGYGFPVDWWSLGVSLFELLK-KRRPFSVHSNTSLHEM 25
>19094
Length = 898
Score = 56.6 bits (135), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 31/103 (30%), Positives = 54/103 (52%)
Frame = +1
Query: 439 QNRHVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRA 498
+N+ + ++ I +++ G+ YL +HRD+ A N+LL + +AK++DFG++ L
Sbjct: 37 RNKTLVEREIATILYYTLKGL*YLHSRRKIHRDIKAGNILLNNEGHAKLADFGVAGQL-- 210
Query: 499 DENYYKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWE 541
+ K T P W APE I + +D+WS G+ E
Sbjct: 211 TDTMAKRNTVIGTPY-WMAPEVIQEIGYDCVADIWSLGITALE 336
>04591
Length = 1117
Score = 55.8 bits (133), Expect = 5e-08, Method: Compositional matrix adjust.
Identities = 55/221 (24%), Positives = 96/221 (43%), Gaps = 14/221 (6%)
Frame = -2
Query: 395 LAEANVMQQLDNPYIVRMIGICEAE---------SWMLVMEMAE--LGPLNKYLQQNRHV 443
L E ++QQL++ +V++ IC + ++ L+ E + L L L+ +
Sbjct: 1077 LREIKILQQLEHENVVQLQEICHTQAGPYNRYKSTFYLIFEYCDYDLAGLLNNLRVKFSL 898
Query: 444 KDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYY 503
DK L+ Q+ G+ Y+ +HRD+ A N+LL K++DFGLS+ +
Sbjct: 897 ADKK--NLMSQLLNGLFYIHTKQILHRDIKAANILLTRDGVLKLADFGLSRP------WV 742
Query: 504 KAQTHGKWPVK-WYAPE--CINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTA 560
K++ V WY P + ++ + D+W G +M E +S +KP M+G
Sbjct: 741 KSKRLTNRVVTLWYRPPELLLGEREYGPEIDMWGVGCIMAEMWS--RKPL--MQGRSEQH 574
Query: 561 MLEKGERMGCPAGCPREMYDLMNLCWTYDVENRPGFAAVEL 601
L + +LC + + E PG +EL
Sbjct: 573 QLSL----------------ITDLCGSLNAEVWPGVTKLEL 499
>29581
Length = 1278
Score = 55.5 bits (132), Expect = 6e-08, Method: Compositional matrix adjust.
Identities = 44/135 (32%), Positives = 65/135 (48%), Gaps = 4/135 (2%)
Frame = -2
Query: 419 ESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVL 478
+S LVME E + + + +V Q+ G++YL E+ +HRDL N+L
Sbjct: 1130 DSLFLVMEYCEQDLASLLDNMPAPFSESQVKCIVLQLLKGLRYLHEAFIIHRDLKVSNLL 951
Query: 479 LVTQHYAKISDFGLSKALRADENYYKAQ--THGKWPVKWY-APECINYYKFSSKS-DVWS 534
+ + KI+DFGL++ NY K Q K WY APE + K S + D+WS
Sbjct: 950 MTDKGCVKIADFGLAR------NYGKPQKPMTPKVVTLWYRAPELLFGSKTHSTAIDMWS 789
Query: 535 FGVLMWEAFSYGQKP 549
G ++ E G KP
Sbjct: 788 AGCILGELL--GHKP 750
>12672
Length = 773
Score = 54.3 bits (129), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 40/159 (25%), Positives = 74/159 (46%), Gaps = 14/159 (8%)
Frame = +3
Query: 450 ELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFG-LSKALRADENYYKAQTH 508
++V + G++YL ++ VHRD+ N+LL +++ AK+ DF + A + + +
Sbjct: 3 KIVKGTASGIQYLNDNGHVHRDIKTANILLDSEYTAKVGDFATVVSAPSGEGKTVQNASV 182
Query: 509 GKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFS--YGQKPYRGMK--GSEVTAMLEK 564
+ APE I ++ S+K D +SFGV++ E + Q R + S + +E+
Sbjct: 183 VIGTAAYLAPEAI-HFDVSTKLDSYSFGVVLLEVITGLVAQDYSREERTLSSHIMENVEE 359
Query: 565 GERM---------GCPAGCPREMYDLMNLCWTYDVENRP 594
E + P G ++YD+ C + RP
Sbjct: 360 PEEIHDFVDQSAGTWPDGAVDKLYDISMRCLNLSKKQRP 476
>17806
Length = 433
Score = 53.9 bits (128), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 43/123 (34%), Positives = 67/123 (54%), Gaps = 12/123 (9%)
Frame = +1
Query: 352 KELGSGNFGTVKKGYYQ--MKKVVKT-VAVKILKNEANDPALKDELLA---EANVMQQLD 405
KELG+G FG V + + V ++ V VK+LK D A KDE L E ++LD
Sbjct: 67 KELGTGWFGKVIESDAERITTGVSRSKVVVKMLK----DDATKDEQLLFFEEVAPFRELD 234
Query: 406 NPYIVRMIGIC-EAESWMLVMEMAELGPLNKYLQQNRH-----VKDKNIIELVHQVSMGM 459
+P IVR++G C E +++ME A LG L +YL+ +RH ++ +++ +S G+
Sbjct: 235 HPNIVRLLGQCTEMNPMLMLMECAALGNLKQYLRNHRHQQAMLIQKNRLLKFAMDISSGL 414
Query: 460 KYL 462
L
Sbjct: 415 ACL 423
>27546
Length = 426
Score = 50.4 bits (119), Expect = 2e-06, Method: Composition-based stats.
Identities = 26/102 (25%), Positives = 52/102 (50%), Gaps = 1/102 (0%)
Frame = -1
Query: 397 EANVMQQLDNPYIVRMIGICE-AESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQV 455
E ++ +LD+P I+++ I + + M AE G + ++++ + + Q+
Sbjct: 330 ELEILTRLDHPNIIQIHSILQRGPKIFIFMRYAEKGDMLSHIKKTGPIDEAQTKVWFFQM 151
Query: 456 SMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALR 497
+ ++YL + HRDL N+LL + KI+DFG ++ R
Sbjct: 150 AKALQYLHSHDIAHRDLKCENILLSKRLNVKIADFGFARYCR 25
>25550
Length = 941
Score = 49.3 bits (116), Expect(2) = 2e-06, Method: Compositional matrix adjust.
Identities = 23/58 (39%), Positives = 33/58 (56%)
Frame = +3
Query: 550 YRGMKGSEVTAMLEKGERMGCPAGCPREMYDLMNLCWTYDVENRPGFAAVELRLRNYY 607
Y G+ +EV +LE+G RM P G P ++Y LM CW +D + RP F + L N +
Sbjct: 42 YPGVDLTEVYHLLERGYRMERPQGTPADVYILMLKCWQWDPKERPTFKEIHYLLENMF 215
Score = 20.4 bits (41), Expect(2) = 2e-06, Method: Compositional matrix adjust.
Identities = 8/17 (47%), Positives = 10/17 (58%)
Frame = +1
Query: 536 GVLMWEAFSYGQKPYRG 552
GVL+WE +YG G
Sbjct: 1 GVLLWELATYGMSLTLG 51
>19761
Length = 473
Score = 49.7 bits (117), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 31/147 (21%), Positives = 69/147 (46%), Gaps = 2/147 (1%)
Frame = -3
Query: 445 DKNIIELVHQVSMGMKYLEESN--FVHRDLAARNVLLVTQHYAKISDFGLSKALRADENY 502
++ I+ + Q + + Y+ +HRDL +N+ + + ++ D GL++ L ++
Sbjct: 426 ERLIVCWLMQTASALNYMHTHTPVILHRDLKPQNIYVTEKGDVRLGDLGLARKLTGPADF 247
Query: 503 YKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAML 562
+Q + + +PE ++ ++SKSD+WS G + ++ G+K M + +
Sbjct: 246 ATSQVG---TIMYLSPEILSQQPYNSKSDIWSLGCVFYDI--TGKKGSDEMGVMFLLVQV 82
Query: 563 EKGERMGCPAGCPREMYDLMNLCWTYD 589
G ++ P +E D ++ T D
Sbjct: 81 MGGRKLPLPDHYSQEFRDTISRMLTKD 1
>07833
Length = 1504
Score = 49.7 bits (117), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 46/218 (21%), Positives = 94/218 (43%), Gaps = 8/218 (3%)
Frame = -3
Query: 390 LKDELLAEANVMQQLDNPYIVRMIGIC-EAESWMLVMEMAELGPLNKYLQ-QNRHVKDKN 447
+ + + E ++ ++P ++ ++ C + + +L+ + G L L ++ V D+N
Sbjct: 1490 ITRDFMEEFPRLRIFNHPNVLPVLACCNQPPNLVLISQFMPFGSLYNTLHGESGIVVDQN 1311
Query: 448 -IIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQ 506
+ ++ GM++L + N LL ++H + D L+ + + +
Sbjct: 1310 QSLRFAMDIARGMEFLHSM-----EPTIPNFLLTSKHV--MIDEDLTARINMADYCFSFH 1152
Query: 507 THGK-WPVKWYAPECINYYK---FSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAML 562
GK + W APE + + +D+WSF +LMWE + P+ + EV +
Sbjct: 1151 EKGKVYSPAWMAPEALQRRPDDINTRAADMWSFAILMWE-LETREVPFAELSSMEVGMKV 975
Query: 563 E-KGERMGCPAGCPREMYDLMNLCWTYDVENRPGFAAV 599
+G R+ P G M L+ +C + RP F +
Sbjct: 974 ALEGLRISIPPGISLHMSRLIKICMNEEPGKRPRFDMI 861
>26560
Length = 398
Score = 48.9 bits (115), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 32/120 (26%), Positives = 59/120 (49%), Gaps = 1/120 (0%)
Frame = -1
Query: 433 LNKYLQQNRHVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGL 492
L+ +L Q+ +K + +V +G++++ V+RDL N+LL + +ISD GL
Sbjct: 395 LHYHLSQHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGL 216
Query: 493 SKALRADENYYKAQTHGKWPVKWYAPECI-NYYKFSSKSDVWSFGVLMWEAFSYGQKPYR 551
+ + THG + APE + + S +D +SFG ++++ G P+R
Sbjct: 215 ACDFSKKRPHASVGTHG-----YMAPEVLMKGQSYDSSADWFSFGCMLYKLLK-GHSPFR 54
>30755
Length = 1137
Score = 48.9 bits (115), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 37/142 (26%), Positives = 61/142 (42%)
Frame = +2
Query: 454 QVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPV 513
++ + YL ++RDL N+LL + K++DFGL K D Y +
Sbjct: 56 EIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCK---EDITYGRTTKTFCGTP 226
Query: 514 KWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAG 573
++ APE ++ + D W GV+M+E G+ P+ + +V L E + P
Sbjct: 227 EYLAPEVLDDNDYGRAVDWWGTGVVMYEMIC-GRLPFYN-RDHDVLFTLILVEDVKFPRN 400
Query: 574 CPREMYDLMNLCWTYDVENRPG 595
E L++ D NR G
Sbjct: 401 ITDEAKSLLSGLLAKDPRNRLG 466
>27405
Length = 532
Score = 47.0 bits (110), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 35/150 (23%), Positives = 70/150 (46%), Gaps = 1/150 (0%)
Frame = -3
Query: 373 VKTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRMIGICEA-ESWMLVMEMAELG 431
+K + K +K + + +E + + V +P+IV M + E ++++ G
Sbjct: 476 MKCLDKKRIKMKGGETLALNERIMLSLVSTGEGSPFIVCMTYAFQTPEKLCFILDLMNGG 297
Query: 432 PLNKYLQQNRHVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFG 491
L+ +L Q+ +K + +V +G++++ V+RDL N+LL + +ISD G
Sbjct: 296 DLHYHLSQHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLG 117
Query: 492 LSKALRADENYYKAQTHGKWPVKWYAPECI 521
L+ + + THG + APE +
Sbjct: 116 LACDFSKKKPHASVGTHG-----YMAPEVL 42
>03240
Length = 1683
Score = 47.0 bits (110), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 48/187 (25%), Positives = 86/187 (45%), Gaps = 11/187 (5%)
Frame = -3
Query: 335 IRPKEVYLDRKLLTLEDKELGSGNFGTV---KKG----YYQMKKVVKTVAVKILKNEAND 387
IR K +D K + + K LG G FG V +K Y MK + K+ +K +N+
Sbjct: 1321 IRLKRAKMD-KCMFEKIKTLGVGAFGEVSLCRKNDTGMLYAMKTLRKSDVLK--RNQVAH 1151
Query: 388 PALKDELLAEANVMQQLDNPYIVRMIGICEAESWM-LVMEMAELGPLNKYLQQNRHVKDK 446
+ ++LAEA DN ++V++ + +++ VM+ G L L + + +
Sbjct: 1150 VKAERDILAEA------DNEWVVKLYYSFQDHNYLYFVMDYVPGGDLMGLLIRMEILDEP 989
Query: 447 NIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADEN---YY 503
V ++ ++ + F+HRD+ N+L+ + K++DFGL R N Y
Sbjct: 988 LARFYVAELVQAIESVHRMGFIHRDIKPDNILIDRNGHIKLTDFGLCTGFRWTHNSKYYQ 809
Query: 504 KAQTHGK 510
+ TH +
Sbjct: 808 RDGTHAR 788
>01966
Length = 1735
Score = 46.6 bits (109), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 40/169 (23%), Positives = 78/169 (46%), Gaps = 4/169 (2%)
Frame = -1
Query: 374 KTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRMIG-ICEAESWMLVMEMAELGP 432
+ +A+K ++ ++ + + E ++++L + IV + I E E LV E +
Sbjct: 1633 RKLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTNIVCLEDVIMEDERLFLVFEFLSMD- 1457
Query: 433 LNKYLQQNRH--VKDKNIIE-LVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISD 489
L Y+ + V D+ +++ V Q+ G+ + + VHRDL +N+L+ KI+D
Sbjct: 1456 LKMYIDKFPEGVVLDRRLVKSYVFQIVTGINFCHQRRIVHRDLKPQNLLINHTGAIKIAD 1277
Query: 490 FGLSKALRADENYYKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFGVL 538
FG+++ Y + W + APE + + S W+ G L
Sbjct: 1276 FGMARTFALPVRAYTHEVVTLW---YRAPEILMGPQ--STPPXWTCGAL 1145
>15910
Length = 1361
Score = 45.8 bits (107), Expect = 5e-05, Method: Compositional matrix adjust.
Identities = 34/125 (27%), Positives = 60/125 (48%), Gaps = 3/125 (2%)
Frame = +2
Query: 445 DKNIIELVHQVSMGMKYLEESNFVHRDLAARNVL---LVTQHYAKISDFGLSKALRADEN 501
+K+ + + G++Y+ + VHRDL N+L + K++DFGLS+ + E
Sbjct: 461 EKDAARAISDILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLADFGLSRII---EP 631
Query: 502 YYKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAM 561
+ T P + APE + K++ D+WS GV+ + G +P+ E+
Sbjct: 632 EVQMSTVCGTP-GYCAPEVLKGDKYTPSVDMWSVGVIAYILLC-GYEPFFAENEFEMYRK 805
Query: 562 LEKGE 566
+ KGE
Sbjct: 806 IIKGE 820
>07836
Length = 1478
Score = 45.8 bits (107), Expect = 5e-05, Method: Compositional matrix adjust.
Identities = 37/140 (26%), Positives = 66/140 (47%), Gaps = 18/140 (12%)
Frame = -1
Query: 420 SW---MLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSMGMKYLEESNF--------V 468
SW L+ + E G L+ YL +R + ++ L H G+ +L F
Sbjct: 1340 SWTQLFLITDYHENGSLHDYLL-SRVLDSSEMLALAHSAICGLAHLHIEIFGTRGKPAIA 1164
Query: 469 HRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWY-APEC----INY 523
HRD+ ++N+L+ I+D GL+ ++ N + + K Y APE +N
Sbjct: 1163 HRDIKSKNILVKKNGTCCIADLGLAVRYISESNEVDVAPNPRQGTKRYMAPEVLEMLLNV 984
Query: 524 YKFSS--KSDVWSFGVLMWE 541
F + ++D+++FG++MWE
Sbjct: 983 KNFDAFKQADMYAFGLVMWE 924
>26711
Length = 405
Score = 45.8 bits (107), Expect = 5e-05, Method: Composition-based stats.
Identities = 33/110 (30%), Positives = 52/110 (47%), Gaps = 3/110 (2%)
Frame = -2
Query: 451 LVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKIS--DFGLSKALRA-DENYYKAQT 507
+V QV ++++ VH DL N+LL + DFGL++ L E + T
Sbjct: 401 VVKQVLDILQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARKLYPPQETFLNHGT 222
Query: 508 HGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSE 557
G + +PE ++ S+ SDVW GVL + S GQ P++ +E
Sbjct: 221 PG-----FTSPEALDVKPISTASDVWGVGVLAYILLS-GQSPFQADSATE 90
>28157
Length = 400
Score = 45.4 bits (106), Expect = 7e-05, Method: Compositional matrix adjust.
Identities = 40/126 (31%), Positives = 61/126 (48%), Gaps = 8/126 (6%)
Frame = +3
Query: 374 KTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRMIGICEAESWMLVMEMAELGPL 433
K VAVK +++E K + E + ++ +P IV + G C LVME AE G L
Sbjct: 3 KDVAVKRIESEQE----KKSFMQELKQLSRVSHPNIVCLYGACRDHPVCLVMEYAEGGSL 170
Query: 434 NKYLQ----QNRHVKDKNIIELVHQVSMGMKYL---EESNFVHRDLAARNVLLV-TQHYA 485
L Q ++ + L+ Q ++G++YL + +HRDL N+LL+
Sbjct: 171 YNVLHGSGPQPQYTAAHAMNWLL-QCALGVEYLHGMKPKALIHRDLKPPNLLLIQCGTKL 347
Query: 486 KISDFG 491
KI DFG
Sbjct: 348 KICDFG 365
>04138
Length = 800
Score = 45.1 bits (105), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 24/86 (27%), Positives = 43/86 (50%), Gaps = 2/86 (2%)
Frame = +1
Query: 461 YLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPE- 519
Y+ + +HRD+ A N+L+ Q K++DFGL++A + T+ + WY P
Sbjct: 58 YIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTN-RVVTLWYRPPE 234
Query: 520 -CINYYKFSSKSDVWSFGVLMWEAFS 544
+ +S+ D W G +M E ++
Sbjct: 235 LLLGDRNYSTAIDQWGAGCIMAEMWT 312
>01392
Length = 1806
Score = 43.9 bits (102), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 30/130 (23%), Positives = 57/130 (43%), Gaps = 13/130 (10%)
Frame = -1
Query: 442 HVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHY-----AKISDFGLSKAL 496
H+ ++ +V ++ + +L HRDL N+L +H KI DF L+ +
Sbjct: 1803 HLCEREASLVVRHIARALDFLHSKGIAHRDLKPENIL--CEHLDDVVPVKICDFDLASGI 1630
Query: 497 RADENYYKAQTHGKWPV---KWYAPECI-----NYYKFSSKSDVWSFGVLMWEAFSYGQK 548
D + K PV ++ APE + + + + + D+WS G++++ G
Sbjct: 1629 SCDGDGTKTPELLT-PVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILYIMLC-GYP 1456
Query: 549 PYRGMKGSEV 558
P+ G G +
Sbjct: 1455 PFYGQCGEDC 1426
>11228
Length = 2155
Score = 42.7 bits (99), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 26/80 (32%), Positives = 41/80 (51%)
Frame = -2
Query: 5 GMADSANHLPFFFGNITREEAEDYLVQGGMSDGLYLLRQSRNYLGGFALSVAHGRKAHHY 64
G + LP+F +++EEA + L+ G +G +L+RQS NY G ++L + +
Sbjct: 1494 GDYEPVESLPYFHSCLSKEEAVEKLMLAG--EGSFLVRQSENYPGDYSLFFLCEKDVRRF 1321
Query: 65 TIERELNGTYAIAGGRTHAS 84
IER G + GGR S
Sbjct: 1320 RIERR--GNQFLVGGRLFDS 1267
>12786
Length = 460
Score = 42.4 bits (98), Expect = 6e-04, Method: Compositional matrix adjust.
Identities = 30/117 (25%), Positives = 50/117 (42%), Gaps = 20/117 (17%)
Frame = -3
Query: 458 GMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYA 517
+K L +H DL N +LV + K+ DFG++ L+ D+ + P + +
Sbjct: 374 AVKALHNEGVIHSDLKPANFMLVAGNL-KLIDFGIANTLQQDKTSVLKDSRVGTP-SYMS 201
Query: 518 PECINY--------------------YKFSSKSDVWSFGVLMWEAFSYGQKPYRGMK 554
PE I YK +SDVWS G +++ YG+ P++ +K
Sbjct: 200 PEAIMAACDDSADDSMEEDGHRTKPKYKVGVRSDVWSLGCILYN-MVYGRTPFQHIK 33
>11185
Length = 473
Score = 42.0 bits (97), Expect = 8e-04, Method: Compositional matrix adjust.
Identities = 32/112 (28%), Positives = 51/112 (45%), Gaps = 19/112 (16%)
Frame = +1
Query: 452 VHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKA--LRADENYYK-AQTH 508
+H V+ G+ Y+ + DL VLL T K +DFGLSK +E ++K A+
Sbjct: 22 IHLVT-GLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAG 198
Query: 509 GKWPVK----------------WYAPECINYYKFSSKSDVWSFGVLMWEAFS 544
+W ++ + APE + S SD+W+ G + +E FS
Sbjct: 199 DQWNIQSAEEMMKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFS 354
>10546
Length = 790
Score = 41.2 bits (95), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 27/86 (31%), Positives = 44/86 (51%), Gaps = 6/86 (6%)
Frame = +2
Query: 165 KMPWFHGKISREESEQIVLIGSKTNGKFLIRARDNNGS--YALCLLHEGKVLHYRIDKDK 222
K W+HG I R + E +V K +G FL+R D + Y L + H+G V + RI
Sbjct: 317 KYEWYHGHIERSKGENLVKHVGK-DGTFLVRVSDKDPKFPYTLVVYHKGSVNNLRIRLRP 493
Query: 223 TGKLSIPEGKK----FDTLWQLVEHY 244
K+++ + KK F + ++EH+
Sbjct: 494 DDKVALGDEKKGEIAFQDVAAMIEHH 571
>30231
Length = 340
Score = 39.7 bits (91), Expect = 0.003, Method: Composition-based stats.
Identities = 30/78 (38%), Positives = 43/78 (55%), Gaps = 8/78 (10%)
Frame = -2
Query: 189 NGKFLIRARDN-NGSYALCLLHEGKVLHYRIDKDKTGKLSI-PEGK----KFDTLWQLVE 242
+G FL+R ++ + +Y LCLL + +V YRI DK G+LS+ EG F L L++
Sbjct: 252 DGSFLVRDSESVSNAYVLCLLFQLRVHQYRILPDKDGRLSVQSEGDMQPLSFIDLPSLIQ 73
Query: 243 HYSYKAD--GLLRVLTVP 258
Y K D GL+ L P
Sbjct: 72 VYISKGDKNGLICPLRRP 19
>13840
Length = 446
Score = 38.9 bits (89), Expect = 0.007, Method: Compositional matrix adjust.
Identities = 36/128 (28%), Positives = 67/128 (52%), Gaps = 8/128 (6%)
Frame = -1
Query: 353 ELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRM 412
E+G GN+GTV K +++ V +AVK +++ + K L+ VM+ + P+IV+
Sbjct: 374 EIGRGNYGTVNKMRHKITSTV--MAVKRIRSTVEEREQKQLLMDLDVVMRSNNCPFIVQF 201
Query: 413 IGIC--EAESWMLVMEMAELGPLNKYLQ----QNRHVKDKNIIELVHQVSM-GMKYL-EE 464
G E + W + ME+ E L+K+ + + + +NI+ + ++ + YL EE
Sbjct: 200 YGALFKEGDCW-ICMELME-TSLDKFYKFVYGEMQSSIPENILGKITVATLKALNYLKEE 27
Query: 465 SNFVHRDL 472
+HRD+
Sbjct: 26 LRIIHRDV 3
>21433
Length = 590
Score = 38.1 bits (87), Expect = 0.010, Method: Composition-based stats.
Identities = 28/98 (28%), Positives = 44/98 (44%)
Frame = +2
Query: 452 VHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKW 511
++Q+S ++Y +HRD+ N+LL + KI+DFG S + T
Sbjct: 185 IYQLSSALEYCHYRKVIHRDIKPENLLLGLKGDLKIADFGWSVHAPSSRRTTMCGT---- 352
Query: 512 PVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKP 549
+ + PE + D+WS GVL +E F G P
Sbjct: 353 -LDYLPPEMVEGKTHDENVDLWSLGVLCYE-FLVGTPP 460
>04627
Length = 572
Score = 37.7 bits (86), Expect = 0.013, Method: Compositional matrix adjust.
Identities = 21/56 (37%), Positives = 30/56 (53%), Gaps = 2/56 (3%)
Frame = +3
Query: 165 KMPWFHGKISREESEQIVLIGSKTNGKFLIRARDNNGS--YALCLLHEGKVLHYRI 218
K W+HG I R + E +V K +G FL+R D + Y L + H+G V + RI
Sbjct: 348 KYEWYHGHIERSKGENLVKHVGK-DGTFLVRVSDKDPKFPYTLVVYHKGSVNNLRI 512
>35671
Length = 567
Score = 37.7 bits (86), Expect = 0.014, Method: Compositional matrix adjust.
Identities = 17/45 (37%), Positives = 22/45 (48%)
Frame = -3
Query: 563 EKGERMGCPAGCPREMYDLMNLCWTYDVENRPGFAAVELRLRNYY 607
+KG R+ P C E Y +M CWT E RP F + + N Y
Sbjct: 565 QKGNRLAKPISCTDEAYKVMLQCWTESREERPTFKKLVPVMENLY 431
>00394
Length = 548
Score = 37.0 bits (84), Expect = 0.022, Method: Compositional matrix adjust.
Identities = 32/103 (31%), Positives = 50/103 (48%), Gaps = 6/103 (5%)
Frame = -2
Query: 343 DRKLLTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQ 402
D + L DKE+G G+F TV KG V VA L+++ + A + EA +++
Sbjct: 304 DNRFLKF-DKEIGRGSFKTVYKGLDTELGV--AVAWCELQDKKWNKAERQRFKEEAEMLK 134
Query: 403 QLDNPYIVRMIGICEAES------WMLVMEMAELGPLNKYLQQ 439
+L +P IVR E + +LV E+ G L YL++
Sbjct: 133 ELQHPNIVRFFDYWEEHNHRNRKVIILVTELMTSGTLKTYLKR 5
>18881
Length = 762
Score = 36.2 bits (82), Expect = 0.038, Method: Compositional matrix adjust.
Identities = 19/58 (32%), Positives = 32/58 (55%), Gaps = 2/58 (3%)
Frame = -3
Query: 189 NGKFLIRARDNNGSYALCLLH--EGKVLHYRIDKDKTGKLSIPEGKKFDTLWQLVEHY 244
+G FLIR N + C + V H +++++ G+ + +G FD++ QLVEHY
Sbjct: 745 DGTFLIRVT-NTSARESCPQY*YANAVRHIKVNRNPQGRFYLADGHYFDSVQQLVEHY 575
>18481
Length = 437
Score = 35.8 bits (81), Expect = 0.048, Method: Composition-based stats.
Identities = 44/129 (34%), Positives = 65/129 (50%), Gaps = 8/129 (6%)
Frame = -1
Query: 374 KTVAVKILKNEANDPALKDELLA-EANVMQQLD-NPYIVRMIGI-CEAESWMLVMEMAEL 430
K +AVKI EA D +K +LL EA V +Q+ +P + M E LVME+ L
Sbjct: 407 KDIAVKI---EAID--VKHQLLHYEAKVYEQIGRHPGLPTMYHYGTEKHFNALVMEL--L 249
Query: 431 GPLNK--YLQQNRHVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQ---HYA 485
GP + ++ R K I+ + Q+ ++++ + F+HRDL N L+ H
Sbjct: 248 GPSLEELFVICKRRFTLKTILMVSDQLLSRLEFIHQKCFIHRDLKPDNFLMGLGRHCHRL 69
Query: 486 KISDFGLSK 494
I DFGLSK
Sbjct: 68 YIIDFGLSK 42
>31489
Length = 329
Score = 35.4 bits (80), Expect = 0.064, Method: Composition-based stats.
Identities = 14/46 (30%), Positives = 30/46 (65%)
Frame = +3
Query: 433 LNKYLQQNRHVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVL 478
L++ + ++ + +++I ++Q+ G+KY+ +N VHRDL N+L
Sbjct: 126 LHRIIYSDQPLTEEHIRYFLYQILRGLKYIHSANVVHRDLKPSNLL 263
>31789
Length = 676
Score = 34.7 bits (78), Expect = 0.10, Method: Compositional matrix adjust.
Identities = 40/151 (26%), Positives = 68/151 (45%), Gaps = 9/151 (5%)
Frame = +2
Query: 318 LPMDTEVYESPYADP-EEIRPKEVYL--DRKLLTLEDKELGSGNFGTVKKGYYQMKKVVK 374
L ++ E+ + A +EI K V D + L D E+G G+F TV KG V
Sbjct: 230 LQLEGEIKDIQQAQKVQEIEEKAVASSPDNRFLKF-DVEIGRGSFKTVYKGLDTELGVA- 403
Query: 375 TVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRMIGICEAES------WMLVMEMA 428
VA L+++ + + EA ++++L +P IVR E + +LV E+
Sbjct: 404 -VAWCELQDKKWNKTERQRFKEEAEMLKELQHPNIVRFFDYWEEHNHRNRKVIILVTELM 580
Query: 429 ELGPLNKYLQQNRHVKDKNIIELVHQVSMGM 459
G L YL++ + + K + Q+ G+
Sbjct: 581 TSGTLKTYLKRFKKINLKVLKNWCRQILKGL 673
>14257
Length = 919
Score = 33.9 bits (76), Expect = 0.20, Method: Compositional matrix adjust.
Identities = 23/83 (27%), Positives = 43/83 (51%), Gaps = 2/83 (2%)
Frame = -3
Query: 168 WFHGKISREESEQIVLIGSKTNGKFLIRARDNNGS-YALCLLHEGKVLH-YRIDKDKTGK 225
W+HGKI R+E+E+++ + +G FL+R N+ + + L G V H +D D +
Sbjct: 890 WYHGKIGRKEAEKLL----ELDGDFLVREASNSAAQFVLSGRQNGNVRHLLLVDPDGIVR 723
Query: 226 LSIPEGKKFDTLWQLVEHYSYKA 248
+ FD++ L+ ++ A
Sbjct: 722 ---TKDFIFDSVSHLINYHRQNA 663
>26009
Length = 886
Score = 33.5 bits (75), Expect = 0.24, Method: Compositional matrix adjust.
Identities = 11/51 (21%), Positives = 28/51 (54%)
Frame = +3
Query: 438 QQNRHVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKIS 488
++N+ + ++ Q+ + ++ VHRD+ NVL++T ++++S
Sbjct: 687 RRNKACGSREAKSVMKQLVSALDFMHSKQLVHRDIKPENVLILTPDFSRVS 839
>16708
Length = 1397
Score = 33.1 bits (74), Expect = 0.35, Method: Compositional matrix adjust.
Identities = 27/118 (22%), Positives = 52/118 (44%), Gaps = 11/118 (9%)
Frame = -1
Query: 423 LVMEMAELGPL-NKYLQQNRHVKDKN----------IIELVHQVSMGMKYLEESNFVHRD 471
+++ E+GPL N Y H K+K + + Q ++++ E VH D
Sbjct: 1184 ILLHFYEMGPLCNVY----AHYKNKEMPIRWSNPAMVCCIAGQXVCALEHIHELGVVHMD 1017
Query: 472 LAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINYYKFSSK 529
+ A NVL+ K++D+G+++ + Y A P + ++ C N F ++
Sbjct: 1016 VKADNVLVDAHGNCKLTDYGIAQLYKV----YPA------PTETHSSGCTNKRTFYTR 873
>38046
Length = 446
Score = 32.7 bits (73), Expect = 0.39, Method: Composition-based stats.
Identities = 11/25 (44%), Positives = 19/25 (76%)
Frame = -1
Query: 455 VSMGMKYLEESNFVHRDLAARNVLL 479
++ M Y+E+ NF+HR+L RN+L+
Sbjct: 98 IADAMAYMEKENFIHRNLGDRNILV 24
>21210
Length = 518
Score = 32.3 bits (72), Expect = 0.52, Method: Compositional matrix adjust.
Identities = 25/91 (27%), Positives = 42/91 (46%), Gaps = 9/91 (9%)
Frame = +3
Query: 515 WYAPECIN----YYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGC 570
+ APE I+ + + +SDVWS G+ + E + G+ PYR K + L++ R
Sbjct: 18 YMAPERIDPRASSHGYDVRSDVWSLGITLME-LATGRFPYR--KWVSIFDQLQQVVRGVA 188
Query: 571 PA-----GCPREMYDLMNLCWTYDVENRPGF 596
P + + +N C T D + RP +
Sbjct: 189 PCLPHDGAFSHDFVNFVNKCLTKDEKQRPKY 281
>15741
Length = 402
Score = 32.3 bits (72), Expect = 0.56, Method: Composition-based stats.
Identities = 13/33 (39%), Positives = 20/33 (60%)
Frame = -3
Query: 446 KNIIELVHQVSMGMKYLEESNFVHRDLAARNVL 478
++ V+ GM ++ + VHRD+AARNVL
Sbjct: 100 RDFFSFALHVARGMAHVANNKIVHRDVAARNVL 2
>36481
Length = 806
Score = 32.3 bits (72), Expect = 0.60, Method: Compositional matrix adjust.
Identities = 38/152 (25%), Positives = 67/152 (44%), Gaps = 19/152 (12%)
Frame = +2
Query: 355 GSGNFGTVKKGYYQMKKVVK--TVAVKILKNEANDPALKDELLAEANVMQQL--DNPY-- 408
G G FG V Q K ++K +A+KI+KN ++ E NV+++L +P+
Sbjct: 389 GEGTFGKV----VQCKDLLKGDDIALKIIKNV---DKYREAAKLEINVLEKLREKDPHAK 547
Query: 409 --IVRMIG-------ICEAESWMLVMEMAELGPLNKY----LQQNRHVKDKNIIELVHQV 455
V+M+ +C + ML + + + N Y ++Q RH+ +Q+
Sbjct: 548 HMCVQMLDWFDYHGHVCISFH-MLGLSVFDFLKDNSYGAYPIEQVRHIS--------YQL 700
Query: 456 SMGMKYLEESNFVHRDLAARNVLLVTQHYAKI 487
+ +L E+ H DL N+L V Y +
Sbjct: 701 CYAVNFLHENQLTHTDLKPENILFVDSQYENV 796
>18401
Length = 463
Score = 32.0 bits (71), Expect = 0.77, Method: Compositional matrix adjust.
Identities = 17/48 (35%), Positives = 26/48 (54%)
Frame = -3
Query: 517 APECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEK 564
APE I +S DVWS G +M+E ++ G ++ E AM+E+
Sbjct: 428 APEVILELGWSHPCDVWSVGCIMFELYT-GYTLFQTHDNKEHLAMMER 288
>00191
Length = 1400
Score = 31.6 bits (70), Expect = 1.00, Method: Compositional matrix adjust.
Identities = 16/39 (41%), Positives = 21/39 (53%)
Frame = -1
Query: 346 LLTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKNE 384
L L D LG NF K G+ +KKV+KT+ KN+
Sbjct: 1130 LXCLADPCLGVRNFRDTKSGFPPLKKVMKTITKPYXKNK 1014
>29590
Length = 320
Score = 31.2 bits (69), Expect = 1.3, Method: Composition-based stats.
Identities = 14/46 (30%), Positives = 26/46 (56%)
Frame = +3
Query: 515 WYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTA 560
+ APE ++Y S ++D+WS GVL + + P+ G+ + +A
Sbjct: 72 YVAPEVLDYEPLSIQTDMWSLGVLSYVMLT-ACSPFVGITSKKHSA 206
>25019
Length = 730
Score = 30.4 bits (67), Expect = 1.9, Method: Compositional matrix adjust.
Identities = 20/68 (29%), Positives = 28/68 (41%), Gaps = 4/68 (5%)
Frame = +3
Query: 473 AARNVLLVTQHYAKISDFGLSK----ALRADENYYKAQTHGKWPVKWYAPECINYYKFSS 528
AA NVLL + K++DFGL K R + +++ APE +
Sbjct: 255 AAENVLLDKDGHVKLTDFGLCKEAITGTRVTHTFCGT-------IEYMAPEILTRTGHGK 413
Query: 529 KSDVWSFG 536
D WS G
Sbjct: 414 AVDWWSLG 437
>02638
Length = 1490
Score = 30.4 bits (67), Expect = 2.3, Method: Compositional matrix adjust.
Identities = 26/97 (26%), Positives = 39/97 (40%), Gaps = 4/97 (4%)
Frame = +1
Query: 503 YKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAML 562
++ Q G + + APE + + DVWS G +M E + + P+ S A++
Sbjct: 4 FQGQLLGT--IAFMAPEVLRGESYGRACDVWSVGCVMIEMCTC-RPPWNSHDISNHLALI 174
Query: 563 EKGERMGCPAGCPREMY----DLMNLCWTYDVENRPG 595
K P P M DLM C D + RP
Sbjct: 175 FKIASSVDPPPIPENMSPPVRDLMLRCLEQDSDFRPS 285
>37602
Length = 804
Score = 30.0 bits (66), Expect = 2.6, Method: Compositional matrix adjust.
Identities = 17/72 (23%), Positives = 30/72 (41%)
Frame = -1
Query: 419 ESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVL 478
E + ME G + + + I + + G+ YL +HRD+ N+L
Sbjct: 300 EKLWIAMEYCGGGSMQDIYHVTGPLTEPQIAFVCRETLKGLHYLHRRGKMHRDIKGANIL 121
Query: 479 LVTQHYAKISDF 490
L + K++DF
Sbjct: 120 LTEEGDVKLADF 85
>07933
Length = 728
Score = 29.6 bits (65), Expect = 3.8, Method: Compositional matrix adjust.
Identities = 11/30 (36%), Positives = 17/30 (56%)
Frame = +3
Query: 571 PAGCPREMYDLMNLCWTYDVENRPGFAAVE 600
P CP +Y++M CW+ + RP F +E
Sbjct: 3 PNYCPNLLYNIMMQCWSAEPSARPTFHKLE 92
>14799
Length = 565
Score = 29.6 bits (65), Expect = 4.0, Method: Composition-based stats.
Identities = 17/43 (39%), Positives = 21/43 (48%)
Frame = -3
Query: 346 LLTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDP 388
L L D LG NF K G+ +KKV+KT+ K N P
Sbjct: 302 LRCLADPCLGVRNFRDTKSGFPPLKKVMKTITKPYNKKXKNRP 174
>30740
Length = 488
Score = 28.5 bits (62), Expect = 9.1, Method: Composition-based stats.
Identities = 21/74 (28%), Positives = 38/74 (51%), Gaps = 3/74 (4%)
Frame = +2
Query: 203 YALCLLHEGKVLHYRIDKDKTGKLSIPE--GKKFDTLWQLVEHY-SYKADGLLRVLTVPC 259
+ LC+ + KV HY I++ + G L+ + K+F+ + L+ Y S+ D + P
Sbjct: 5 FVLCVKEDSKVSHYIINRIQVGGLTRFKIGDKEFNDIPSLLNFYKSHYLDTTTLIRPAPR 184
Query: 260 QKIGTQGNVNFGGR 273
+K+ G +F GR
Sbjct: 185 EKL--MGKYDFSGR 220
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000381740 | hsapiens_gene_ensembl | Poly
[ADP-ribose] polymerase 3 (EC 2.4.2.30) (PARP-3) (NAD(+) ADP-
ribosyltransferase 3) (Poly[ADP-ribose] synthetase 3) (pADPRT-3)
(hPARP-3) (IRT1). [Source:Uniprot/SWISSPROT;Acc:Q9Y6F1]
(533 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
06293 180 9e-57
07234 97 2e-20
10167 60 1e-18
04480 67 1e-11
11193 67 2e-11
32072 41 0.002
05693 28 7.7
>06293
Length = 2053
Score = 180 bits (457), Expect(2) = 9e-57, Method: Compositional matrix adjust.
Identities = 122/384 (31%), Positives = 187/384 (48%), Gaps = 9/384 (2%)
Frame = +2
Query: 24 REEDPFRSTAEALKAIPAEKRIIRVDPTCPLSSNPGTQVYED----YXXXXXXXXXXXXX 79
REE+ T ++ + K VD CPL+ +VYE +
Sbjct: 68 REENGSGDTKSVVRQVVVNKGSAPVDAECPLAGK--CRVYEAASTIWDCMLNQTNVGNNN 241
Query: 80 XKFYIIQLLQD-SNRFFTCWNHWGRVGEVGQSK-INHFTRLEDAKKDFEKKFREKTKNNW 137
K+YIIQ+L+D S + + W WGRVG GQ+ +N L A F KKF++KTKN+W
Sbjct: 242 NKYYIIQVLEDTSKKAYHVWQRWGRVGYKGQTNLVNTGGDLNKAIDVFSKKFQDKTKNHW 421
Query: 138 AERDHFVSHPGKYTLIXXXXXXXXXXXXXXXXRGPVRTVTKRVQPCSLDPATQKLITNIF 197
R++F+ PGKY L+ G + L Q L+ I
Sbjct: 422 NNRNNFLKVPGKYDLVHLDYSAKEEDQVDAGEAGD--NEDSQAPDSKLHQKVQDLVKMIC 595
Query: 198 SKEMFKNTMALMDLDVKKMPLGKLSKQQIARGFXXXXXXXXXXKGPTDGGQSLEELSSHF 257
+ + + M D KK PLGKL+K QI G+ D G++L + S F
Sbjct: 596 DVKSMEEAVVEMKYDAKKAPLGKLTKDQITAGYESLKEIESLI-NTKDFGRNLTDACSEF 772
Query: 258 YTVIPHNFGHSQPPPINSPELLQAKKDMLLVLADIELAQALQAVSEQEKTVEEVPHPLDR 317
YT IPH+FG PP I +P+ ++ K +L L DI+ A++ + + +K+ +P+DR
Sbjct: 773 YTRIPHDFGMRTPPVIRTPKEVKEKLQLLEALEDIQY--AIKMLKQGDKS----ENPVDR 934
Query: 318 DYQLLKCQLQLLDSGAPEYKVIQTYLEQTGS---NHRCPTLQHIWKVNQEGEEDRFQAHS 374
Y L C L LD G+ ++K+I++YL +T + N L ++ V+++GE++R+ +
Sbjct: 935 HYHSLACALSPLDHGSDDFKLIESYLLETHAATHNQYKMKLLELYDVDKQGEKERYLDY- 1111
Query: 375 KLGNRKLLWHGTNMAVVAAILTSG 398
GNR LLWHG+ + A IL G
Sbjct: 1112--GNRMLLWHGSRLTNWAGILGQG 1177
Score = 58.5 bits (140), Expect(2) = 9e-57, Method: Compositional matrix adjust.
Identities = 46/142 (32%), Positives = 67/142 (47%), Gaps = 5/142 (3%)
Frame = +1
Query: 397 SGLRIMPH----SGGRVGKGIYFASENSKSAGYVIGMKCGAHHVGYMFLGEVALGR-EHH 451
SGLRI P +G GKG+YFA +SKSA Y K +VG M L +V+LG
Sbjct: 1171 SGLRIAPPEAPVTGYMFGKGVYFADMSSKSANYCFASK--QKNVGMMLLCDVSLGNINEK 1344
Query: 452 INTDNPSLKSPPPGFDSVIARGHTEPDPTQDTELELDXXXXXXXXXXXXXXXEFSSSTFS 511
++ D + K P G SV G PDP+ + + D T +
Sbjct: 1345 LDADYYADKL-PSGKHSVKGCGSVGPDPST-FKTQPDGLVVPVGKGTNTGVTNPKGYTLN 1518
Query: 512 QSEYLIYQESQCRLRYLLEVHL 533
+E+++Y +Q R++YLL+V
Sbjct: 1519 YNEFIVYNTAQIRMKYLLKVQF 1584
>07234
Length = 543
Score = 97.1 bits (240), Expect = 2e-20, Method: Compositional matrix adjust.
Identities = 65/171 (38%), Positives = 91/171 (53%), Gaps = 7/171 (4%)
Frame = -2
Query: 314 PLDRDYQLLKCQLQLLDSGAPEYKVIQTYLEQT-GSNHRCPTLQ--HIWKVNQEGEEDRF 370
P+D Y+ LKC ++ LD+ +K + Y++ T + H+ TL I+++++EGE +F
Sbjct: 506 PIDAHYKKLKCTMEPLDNKGDMFKRLCEYVQNTHAATHQQYTLDVLDIFEMDREGETQQF 327
Query: 371 QAHSKLGNRKLLWHGTNMAVVAAILTSGLRI----MPHSGGRVGKGIYFASENSKSAGYV 426
+ L NR+LLWHG+ A IL+ GLRI P +G GKGIYFA SKSA Y
Sbjct: 326 EPFKALHNRQLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANYC 147
Query: 427 IGMKCGAHHVGYMFLGEVALGREHHINTDNPSLKSPPPGFDSVIARGHTEP 477
K A +G + L EVALG H + T + P G S G T P
Sbjct: 146 RTSK--ADPIGILLLCEVALGNMHEL-TSASYVTKLPKGKHSTKGIGRTTP 3
>10167
Length = 959
Score = 59.7 bits (143), Expect(2) = 1e-18, Method: Compositional matrix adjust.
Identities = 33/97 (34%), Positives = 55/97 (56%)
Frame = -1
Query: 202 FKNTMALMDLDVKKMPLGKLSKQQIARGFXXXXXXXXXXKGPTDGGQSLEELSSHFYTVI 261
K M ++D+KKMPLGKLSK+QI + Q ++ ++ FYT+I
Sbjct: 611 MKKAMMEFEIDMKKMPLGKLSKRQIESAYKVLTELQDLVTKKGTQTQFVDA-TNRFYTLI 435
Query: 262 PHNFGHSQPPPINSPELLQAKKDMLLVLADIELAQAL 298
PH+FG + +++ E +++K +ML L +IE+A +L
Sbjct: 434 PHDFGMGKIKLLDTEEAIKSKTEMLDNLLEIEVAYSL 324
Score = 51.2 bits (121), Expect(2) = 1e-18, Method: Compositional matrix adjust.
Identities = 31/96 (32%), Positives = 54/96 (56%), Gaps = 6/96 (6%)
Frame = -2
Query: 314 PLDRDYQLLKCQLQLLDSGAPEYKVIQTYLEQT-GSNHRCPTLQ--HIWKVNQEGEEDRF 370
P+D Y+ LKC ++ LD+ +K + Y++ T + H+ TL I+++++EGE +F
Sbjct: 295 PIDAHYKKLKCTMEPLDNKGDMFKRLCEYVQNTHAATHQQYTLDVLDIFEMDREGETQQF 116
Query: 371 QAHSKLGNRKLLWHG---TNMAVVAAILTSGLRIMP 403
+ L NR+LLWHG TN+ + + L + P
Sbjct: 115 EPFKALHNRQLLWHGSRTTNLLASCHRVCASLLLRP 8
Score = 28.9 bits (63), Expect = 5.7, Method: Compositional matrix adjust.
Identities = 13/27 (48%), Positives = 16/27 (59%), Gaps = 4/27 (14%)
Frame = -3
Query: 128 KFRE----KTKNNWAERDHFVSHPGKY 150
KFRE KT N+W +R HF P K+
Sbjct: 819 KFRELYLSKTGNDWEQRKHFKKQPNKF 739
>04480
Length = 1878
Score = 67.4 bits (163), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 58/218 (26%), Positives = 101/218 (46%), Gaps = 4/218 (1%)
Frame = -3
Query: 316 DRDYQLLKCQLQLLDSGAPEYKVIQTYLEQTGSNHRCPTLQHIWKVNQEGEEDRFQAHSK 375
D Y+ + ++Q L E + + TY+ +G H C + ++KV++ GE + +
Sbjct: 1828 DYIYRSMGSKIQPLSENEHETQYLLTYINASG--HGC-KVNAVYKVSRPGEVEALK-DVG 1661
Query: 376 LGNRKLLWHGTNMAVVAAILTSGLRI----MPHSGGRVGKGIYFASENSKSAGYVIGMKC 431
L N +LLWHGT+MA + +IL+ GL + P +G G+G+YFA +KS Y
Sbjct: 1660 LHNHRLLWHGTSMANIVSILSRGLLVAPANAPRNGNAFGEGVYFADCFTKSRSYCYN-AV 1484
Query: 432 GAHHVGYMFLGEVALGREHHINTDNPSLKSPPPGFDSVIARGHTEPDPTQDTELELDXXX 491
G+ V M L +VALG + + S+ G +PDP D ++ L
Sbjct: 1483 GSCKV--MLLCQVALGNSLE-DLCHDEEDHHDEDVHSLKVLGCMQPDP--DFDIVLPYGA 1319
Query: 492 XXXXXXXXXXXXEFSSSTFSQSEYLIYQESQCRLRYLL 529
+ + + +EY+++ Q +RY++
Sbjct: 1318 TLPLGQLKKMTYDGKTPSLQYNEYIVHNPQQICIRYII 1205
>11193
Length = 1001
Score = 67.0 bits (162), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 42/141 (29%), Positives = 65/141 (46%), Gaps = 1/141 (0%)
Frame = -2
Query: 82 FYIIQLL-QDSNRFFTCWNHWGRVGEVGQSKINHFTRLEDAKKDFEKKFREKTKNNWAER 140
FY IQ++ Q + + + WGR+G+ GQ + F EDA K+F K FR+KT N+W
Sbjct: 643 FYKIQIVRQKAKDMYVLFTRWGRIGDRGQWQHTPFPTAEDAIKEFCKVFRQKTGNDWNHL 464
Query: 141 DHFVSHPGKYTLIXXXXXXXXXXXXXXXXRGPVRTVTKRVQPCSLDPATQKLITNIFSKE 200
+ FV H KY L+ + PV + L+P+ L+ + S
Sbjct: 463 EKFVEHKKKYRLMPTLEEPKRSKAVTFNFQSPVAS--------KLNPSVLDLLQELTSVT 308
Query: 201 MFKNTMALMDLDVKKMPLGKL 221
M + + LD MP G++
Sbjct: 307 MLQASAKSKGLDEDFMPFGRI 245
>32072
Length = 272
Score = 40.8 bits (94), Expect = 0.002, Method: Composition-based stats.
Identities = 22/50 (44%), Positives = 29/50 (58%), Gaps = 2/50 (4%)
Frame = +1
Query: 81 KFYIIQLLQD-SNRFFTCWNHWGRVGEVGQSK-INHFTRLEDAKKDFEKK 128
K+YIIQ+L+D S + + W WGRVG GQ+ +N L A F KK
Sbjct: 55 KYYIIQVLEDTSKKAYHVWQRWGRVGYKGQTNLVNTGGDLNKAIDVFSKK 204
>05693
Length = 671
Score = 28.5 bits (62), Expect = 7.7, Method: Compositional matrix adjust.
Identities = 15/46 (32%), Positives = 21/46 (45%), Gaps = 2/46 (4%)
Frame = -2
Query: 373 HSKLGNRKLLWHGTNMAVVAAILTSGLR--IMPHSGGRVGKGIYFA 416
+S + N K LWHGT + I G + G+G+YFA
Sbjct: 574 NSGIQNEKTLWHGTGADAIENINNYGFNRSYCGKNATAFGQGVYFA 437
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000378643 | hsapiens_gene_ensembl | Focal adhesion
kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK) (Protein- tyrosine kinase
2). [Source:Uniprot/SWISSPROT;Acc:Q05397]
(927 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
06405 216 3e-56
21808 199 4e-51
11780 122 8e-45
09007 174 2e-43
04852 160 2e-39
14116 147 2e-35
07291 139 6e-33
17300 122 2e-29
20640 125 7e-29
07940 117 2e-26
08294 117 3e-26
18996 109 4e-24
14477 108 9e-24
22005 96 7e-20
18921 96 8e-20
17253 95 1e-19
17637 89 9e-18
00300 89 1e-17
01718 86 5e-17
13305 82 8e-16
19301 82 9e-16
12721 78 2e-14
14420 75 8e-14
13592 75 2e-13
27546 70 4e-12
30755 70 4e-12
31885 69 1e-11
09606 68 1e-11
00715 68 2e-11
07833 67 2e-11
13066 67 3e-11
14126 64 2e-10
01060 64 3e-10
13212 62 1e-09
19094 62 1e-09
29581 61 2e-09
01756 60 5e-09
19761 59 9e-09
04591 59 1e-08
21079 58 2e-08
01707 56 8e-08
18484 56 8e-08
03240 55 9e-08
01966 55 1e-07
07836 55 1e-07
12672 53 6e-07
15910 52 1e-06
26711 52 1e-06
21433 49 1e-05
32264 47 2e-05
25550 47 5e-05
28157 46 6e-05
26560 44 3e-04
04138 44 4e-04
01392 43 5e-04
12786 41 0.002
03508 40 0.005
37602 40 0.006
11185 39 0.010
38046 38 0.016
18481 38 0.018
07933 37 0.030
00486 36 0.065
16708 35 0.13
26009 35 0.14
02638 35 0.16
27405 34 0.24
15741 34 0.31
21210 32 0.89
27287 32 1.1
25019 31 2.6
32359 30 3.2
06601 30 5.8
>06405
Length = 1965
Score = 216 bits (550), Expect = 3e-56, Method: Compositional matrix adjust.
Identities = 111/297 (37%), Positives = 173/297 (58%), Gaps = 2/297 (0%)
Frame = +1
Query: 410 PSTRDYEIQRERIELGRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFL 469
P +EI+R I + +G GQ+GDV++ ++ VA+KT K T FL
Sbjct: 229 PEPDRWEIERTEIAMKHRLGGGQYGDVYEAMWKRYNK---IVAVKTLKEDTM--ALNDFL 393
Query: 470 QEALTMRQFDHPHIVKLIGVIT-ENPVWIIMELCTLGELRSFLQVRKYSLDLASLILY-A 527
+EA M++ HP++V+L+GV T E P +I+ E G L +L+ + + ++Y A
Sbjct: 394 EEAAIMKEMKHPNLVQLLGVCTREPPFYIVTEFMPHGNLLDYLRSSTREENGPTALMYMA 573
Query: 528 YQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIK 587
Q+++ +AYLE+K F+HRD+AARN LV+ ++ VK+ DFGL+R M+D TY K PIK
Sbjct: 574 TQIASGMAYLETKNFIHRDLAARNCLVADSNMVKVADFGLARLMKDDTYTAHIGAKFPIK 753
Query: 588 WMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNC 647
W APE + F RF++ SD+W FGV +WE+ +G+ P+ GV+ +V +E G R+ PP
Sbjct: 754 WTAPEGLAFNRFSTRSDIWAFGVLLWELATYGMSPYPGVELTEVYHLLERGYRMERPPGT 933
Query: 648 PPTLYSLMTKCWAYDPSRRPRFTELKAQLRTLQYWTCEGLGKCCQPIWKSVSDSNRK 704
P +Y LM KCW +DP RP F E+ L + + C+ + K + +++K
Sbjct: 934 PADVYILMLKCWQWDPKDRPTFKEIHFLLENMFEKSS-----ICEEVEKELEKNDKK 1089
>21808
Length = 1011
Score = 199 bits (507), Expect = 4e-51, Method: Compositional matrix adjust.
Identities = 96/225 (42%), Positives = 141/225 (62%), Gaps = 1/225 (0%)
Frame = +1
Query: 446 NPALAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITEN-PVWIIMELCTL 504
N VAIKT K+ T D + FL EA M++ HP +++L V T++ P++II EL
Sbjct: 13 NNTTPVAIKTLKSGTMDP--KDFLAEAQIMKKLRHPKLIQLYAVCTQDDPIFIITELMKN 186
Query: 505 GELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGD 564
G L FLQ + L L +LI Q++ +AYLES+ ++HRD+AARN+LVS N+ VK+ D
Sbjct: 187 GSLLEFLQGKGRVLKLPALIDIGAQIACGMAYLESQNYIHRDLAARNILVSDNNTVKIAD 366
Query: 565 FGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQ 624
FGL+R +++ Y + PIKW APE+ N+ RFT SDVW FG+ + E + +G P+
Sbjct: 367 FGLARVIKEDEYEARVGARFPIKWTAPEAANYNRFTIKSDVWSFGILLTETVTYGRVPYP 546
Query: 625 GVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRF 669
G+ N +V+ ++E+G R+P PP CP LY +M +CW + RP
Sbjct: 547 GMTNAEVLHQVEHGYRMPCPPGCPKPLYDIMLECWRKEEMERPHL 681
>11780
Length = 1713
Score = 122 bits (307), Expect(2) = 8e-45, Method: Compositional matrix adjust.
Identities = 69/179 (38%), Positives = 102/179 (56%), Gaps = 1/179 (0%)
Frame = +3
Query: 417 IQRERIELGRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTMR 476
I + +E+G IG+G FGDV++G+Y VAIK K+ D + FLQEA M
Sbjct: 588 IAXQDLEIGEAIGKGDFGDVYKGMYRGQ-----PVAIKQLKD--KDRGEQSFLQEASVMT 746
Query: 477 QFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVRKYS-LDLASLILYAYQLSTALA 535
H ++V+LIGV+ ++++ E G L +L+ R S + I +A A+
Sbjct: 747 SLRHDNLVRLIGVVLGETIFLVTEFMGKGNLVEYLRSRGRSVITKKDQINFATDTCAAME 926
Query: 536 YLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESI 594
YLESKR VHRD+AARNVLV + K+ DFGL+++ + + + K PIKW APE++
Sbjct: 927 YLESKRLVHRDLAARNVLVHDDGKAKVSDFGLAKFGD----FSQTSVKFPIKWTAPEAL 1091
Score = 77.4 bits (189), Expect(2) = 8e-45, Method: Compositional matrix adjust.
Identities = 33/79 (41%), Positives = 48/79 (60%)
Frame = +1
Query: 598 RFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTK 657
+FTS SD+W FG+ +WEI G P+ + DV+ +E G R+ P CPP +YS+M +
Sbjct: 1102 KFTSKSDMWSFGILLWEIYSFGRVPYPRIPLTDVVMHVERGYRMEAPEGCPPEIYSIMKQ 1281
Query: 658 CWAYDPSRRPRFTELKAQL 676
W DP+ RP F + A+L
Sbjct: 1282 AWELDPNERPTFKSVLARL 1338
>09007
Length = 1440
Score = 174 bits (440), Expect = 2e-43, Method: Compositional matrix adjust.
Identities = 91/267 (34%), Positives = 145/267 (54%), Gaps = 11/267 (4%)
Frame = -1
Query: 417 IQRERIELGRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTMR 476
I ++ + L + +G+G FG V Q I+ + + VA+K ++FL+E M+
Sbjct: 888 ISKDCVALSKSLGQGHFGTVRQAIWTAESGEKVQVAVKCLSKDKIHKDGQEFLKETAIMQ 709
Query: 477 QFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVRK-----YSLDLASLILYAYQLS 531
DH +IV++ GV+ +N I++ + L +RS L+ K + L ++ Q+
Sbjct: 708 MLDHENIVRVYGVVMDNGADIML-VTELAPMRSLLECVKEVSARVDFSVPRLCDFSQQVC 532
Query: 532 TALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKL----PIK 587
++YLESKR VHRD+AARN+L+ S VK+ D G+S + Y S+ + +
Sbjct: 531 DGMSYLESKRLVHRDLAARNILLFSKSKVKISDVGVSGALGAGKEYYQSQQTIHLQNAVA 352
Query: 588 WMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIE--NGERLPMPP 645
W APES F+SASDVW FGV +WE HG +P+ G+ ++ ++ +RL P
Sbjct: 351 WCAPESFRNLCFSSASDVWAFGVLLWEFFTHGFQPWAGLNGQQIMEAVDAPQSQRLEQPD 172
Query: 646 NCPPTLYSLMTKCWAYDPSRRPRFTEL 672
CP Y++M KCW +P RRP F++L
Sbjct: 171 LCPKEYYAVMLKCWEQEPQRRPTFSQL 91
>04852
Length = 1462
Score = 160 bits (406), Expect = 2e-39, Method: Compositional matrix adjust.
Identities = 88/262 (33%), Positives = 140/262 (53%), Gaps = 30/262 (11%)
Frame = +1
Query: 448 ALAVAIKTCKNCTSDSVREKFLQEALTMRQF----DHPHIVKLIGVITEN-PVWIIMELC 502
A VA+K ++ + + F+QE M+ H +IV +G T+ P+W+I+E
Sbjct: 19 ASTVAVKMLRDIVTAVEEQDFVQELQVMKAVKKMGSHINIVNFLGCCTQGGPLWVIVEFA 198
Query: 503 TLGELRSFLQ-----VRKYS-------------------LDLASLILYAYQLSTALAYLE 538
G LR FL+ + Y + +L+ YA+Q++ + +L
Sbjct: 199 KNGNLRDFLESCRDGINGYGKFVSPQDPGWYTKTPGGHVIRRKNLLSYAFQIARGMEFLA 378
Query: 539 SKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRR 598
S++ +HRD+AARNVLV+ +K+ DFGLSR Y K S G+LP+KWMAPE++ R
Sbjct: 379 SRKCIHRDLAARNVLVTEEHVLKIADFGLSR--TGDYYKKRSGGRLPVKWMAPEALFDMR 552
Query: 599 FTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGR-IENGERLPMPPNCPPTLYSLMTK 657
+T+ SDVW FGV +WEI G P+ + N ++ + +++ R+P P LY++M +
Sbjct: 553 YTTKSDVWSFGVVLWEIFSLGGMPYASIPNEELYSKLLDDAYRMPRPELASGNLYAIMER 732
Query: 658 CWAYDPSRRPRFTELKAQLRTL 679
CW PS RP F++L + L
Sbjct: 733 CWLNRPSDRPEFSQLVGHIDRL 798
>14116
Length = 1017
Score = 147 bits (371), Expect = 2e-35, Method: Compositional matrix adjust.
Identities = 85/259 (32%), Positives = 140/259 (54%), Gaps = 19/259 (7%)
Frame = -1
Query: 380 EKQGMRTHAVSVSETDDYAEIID------------EEDTYTMPSTRDYEIQRERIELGRC 427
+ G RT+ + E +DY +D +ED + I RE + +G
Sbjct: 789 DSNGTRTYNLEARE-NDYFNRLDVQGAEAMPLLHIDEDMMKLIENESLLIDREFLTMGEE 613
Query: 428 IGEGQFGDVHQGIYMSPENPA-LAVAIKTCKNCTSDSVR-EKFLQEALTMRQFDHPHIVK 485
IG+G FG V +G PE + VA+KT N + + FLQEAL M+ F H +++
Sbjct: 612 IGKGNFGCVKRGFLTLPEQKGDILVAVKTLHNNNPREIELQSFLQEALIMKDFHHSNVLT 433
Query: 486 LIGV---ITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRF 542
LIG+ + + P+ +++ G+L ++++ ++ + LI+Y ++ + YL +F
Sbjct: 432 LIGICLNLDDMPL-VVLPFMKHGDLLTYIRDDQHQPTIKDLIMYGVDIARGMDYLAGLKF 256
Query: 543 VHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKAS--KGKLPIKWMAPESINFRRFT 600
VHRD+AARN ++ + VK+ DFGL+R + + YY + K KLP+KWMA ES+ +
Sbjct: 255 VHRDLAARNCMLDEDFHVKVADFGLARDIYEKEYYSSENKKAKLPVKWMALESLEKGNYD 76
Query: 601 SASDVWMFGVCMWEILMHG 619
S +DVW +GV +WE+L G
Sbjct: 75 SKTDVWSYGVVLWELLTRG 19
>07291
Length = 833
Score = 139 bits (349), Expect = 6e-33, Method: Compositional matrix adjust.
Identities = 62/164 (37%), Positives = 102/164 (62%), Gaps = 2/164 (1%)
Frame = +1
Query: 518 LDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYY 577
L + L+ + Q++ +AYL+ + VHR++AARN +V+ + ++L D+G++ + +YY
Sbjct: 40 LTVVQLLDFGRQIADGMAYLQEVKVVHRNLAARNCIVTEDGRLQLSDYGVTGSLFPQSYY 219
Query: 578 KA--SKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRI 635
A S + +KWMAPE+I+ F+S SDVW FGV +WE+L G+ P+ V+N+ ++ +
Sbjct: 220 TADDSPARDLVKWMAPETIDNFHFSSKSDVWAFGVVLWELLTRGITPYPDVENSSLLPYL 399
Query: 636 ENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLRTL 679
+ G R+ P P +Y +MT CW P +RP F EL QL+T
Sbjct: 400 KEGHRMKKPKQSPEPVYEMMTACWNESPEQRPDFAELNDQLKTF 531
>17300
Length = 480
Score = 122 bits (305), Expect(2) = 2e-29, Method: Compositional matrix adjust.
Identities = 56/117 (47%), Positives = 78/117 (66%), Gaps = 3/117 (2%)
Frame = +1
Query: 530 LSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDST---YYKASKGKLPI 586
+S+ + L +VHRD+AARN+LV+ K+ DFGLSR +E T Y GK+P+
Sbjct: 1 ISSGMGXLADMGYVHRDLAARNILVNEILVCKVADFGLSREIESDTTEGAYTTKGGKIPV 180
Query: 587 KWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPM 643
+W APE+I +R+FTSASDVW FGV MWE++ +G +P+ N DVI +E G RLP+
Sbjct: 181 RWTAPEAIAYRKFTSASDVWSFGVVMWEVMSYGERPYWNWSNQDVIKAVEKGYRLPL 351
Score = 26.6 bits (57), Expect(2) = 2e-29, Method: Compositional matrix adjust.
Identities = 9/25 (36%), Positives = 14/25 (56%)
Frame = +2
Query: 646 NCPPTLYSLMTKCWAYDPSRRPRFT 670
+CP L+ LM W + S RP+ +
Sbjct: 356 DCPEALHQLMLDAWQKERSHRPKMS 430
>20640
Length = 1492
Score = 125 bits (314), Expect = 7e-29, Method: Compositional matrix adjust.
Identities = 55/140 (39%), Positives = 85/140 (60%), Gaps = 1/140 (0%)
Frame = +1
Query: 542 FVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASK-GKLPIKWMAPESINFRRFT 600
+VHRD+A RN LV + VK+ DFGL+R + YY+ S+ +PI+WM E+I + +F+
Sbjct: 7 YVHRDLATRNCLVGHDLVVKISDFGLARSVHSVDYYRGSEHDAIPIRWMPLEAILYNKFS 186
Query: 601 SASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWA 660
+ SDVW FGV +WEI ++P+ G+ + +V+ ++ G+ L P PP +Y LM +CW
Sbjct: 187 TQSDVWSFGVVLWEIFAFALQPYYGLTHEEVVRFVKEGKVLACPERTPPPMYELMKQCWH 366
Query: 661 YDPSRRPRFTELKAQLRTLQ 680
P+ RP F L L +
Sbjct: 367 RRPATRPSFHTLHKTLENMH 426
>07940
Length = 1336
Score = 117 bits (294), Expect = 2e-26, Method: Compositional matrix adjust.
Identities = 54/111 (48%), Positives = 77/111 (69%), Gaps = 1/111 (0%)
Frame = -3
Query: 523 LILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYY-KASK 581
LI YAYQ++ + YL SK+ +HRD+AARNVLV+ +K+ DFGL+R ++ YY K +
Sbjct: 341 LISYAYQVARGMEYLASKQCIHRDLAARNVLVAEEYVLKIADFGLTRNLQQFDYYRKTTD 162
Query: 582 GKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVI 632
G+LP+KWMAPE++ R++TS SDVW +GV +WEI G P+ V D+
Sbjct: 161 GRLPVKWMAPEALFDRKYTSKSDVWSYGVLLWEIFTLGGNPYPSVPVEDLF 9
Score = 59.3 bits (142), Expect = 7e-09, Method: Compositional matrix adjust.
Identities = 37/114 (32%), Positives = 59/114 (51%), Gaps = 4/114 (3%)
Frame = -3
Query: 403 EEDTYTMPSTRDYEIQRERIELGRCIGEGQFGDVHQGIYMS--PENPALAVAIKTCKNCT 460
E Y +P +E RER+ LG +GEG FG V +G M +N ++ VA+K K
Sbjct: 893 EVSEYDLPLDAKWEFPRERLVLGDRLGEGAFGLVMKGEAMGIFKDNNSVTVAVKMLKEDA 714
Query: 461 SDSVREKFLQEALTMRQFD-HPHIVKLIGVITE-NPVWIIMELCTLGELRSFLQ 512
+D ++E M+ H +I+ L+G T+ +++I+E G LR FL+
Sbjct: 713 TDREMMDLIREMEMMKVIGKHKNIINLLGCCTQRGALYVIVEFAPHGNLRDFLK 552
>08294
Length = 1849
Score = 117 bits (292), Expect = 3e-26, Method: Compositional matrix adjust.
Identities = 65/204 (31%), Positives = 110/204 (53%), Gaps = 12/204 (5%)
Frame = +2
Query: 481 PHIVKLIGVITE-NPVWIIMELCTLGELRSFL-----------QVRKYSLDLASLILYAY 528
P+IV +GV E P ++I E C G+L+ FL R +L L+ +
Sbjct: 887 PNIVHFMGVCREAEPHFLITEYCDWGDLKQFLLATRNDNGRGRGTRVPALALSQKLGMGQ 1066
Query: 529 QLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKW 588
Q++ + L ++ VH D+AARNVL++S +K+ LS + S YY + +P++W
Sbjct: 1067 QVAAGMEALSNQGLVHGDLAARNVLLTSRMQLKVARPALSGDVYASEYYPLHQRLVPLRW 1246
Query: 589 MAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCP 648
+ PE + T+ DVW FGV +WE+L P++ + + +V+ +++ + P+ P
Sbjct: 1247 LPPEGVLEDSATTCGDVWAFGVFLWEVLQLADLPYRLMSDEEVLRSLQHSQAALDSPDAP 1426
Query: 649 PTLYSLMTKCWAYDPSRRPRFTEL 672
P L SL+ +C A PS+RP F+E+
Sbjct: 1427 PALLSLLQRCTAQQPSQRPPFSEI 1498
>18996
Length = 491
Score = 109 bits (273), Expect = 4e-24, Method: Compositional matrix adjust.
Identities = 56/136 (41%), Positives = 82/136 (60%), Gaps = 6/136 (4%)
Frame = +2
Query: 543 VHRDIAARNVLVSSNDCVKLGDFGLSRYME-DSTYYKASKGKLPIKWMAPESINFRRFTS 601
+HRD+AARN+LV + CVK+ DFGL+++ D YY S+ +PIKW +PE+I +F+S
Sbjct: 2 IHRDLAARNILVDRS-CVKISDFGLAQFANADGYYYGISQRDIPIKWYSPEAIETCKFSS 178
Query: 602 ASDVWMFGVCMWEILMHG----VKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYS-LMT 656
SDVW +GV ++E+ G + P + + + R+ GERLP P C +YS LM
Sbjct: 179 YSDVWSYGVTLFEMFSRGEIPNLLPGHDLTQEEFLNRLRKGERLPKPELCSDFVYSELMR 358
Query: 657 KCWAYDPSRRPRFTEL 672
CW P RP F ++
Sbjct: 359 PCWHEMPKSRPTFHQI 406
>14477
Length = 493
Score = 108 bits (270), Expect = 9e-24, Method: Composition-based stats.
Identities = 62/169 (36%), Positives = 102/169 (60%), Gaps = 2/169 (1%)
Frame = -1
Query: 416 EIQRERIELGRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSD-SVREKFLQEALT 474
+IQ + ++LG G FG V +G+ ++ + VAIK KN D SV+ + ++EA
Sbjct: 490 QIQMDELKLG----AGNFGSVMKGV-CRLDDREIPVAIKVLKNADLDPSVQSELIKEAEV 326
Query: 475 MRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTAL 534
M++ DH HIV+LIG+ + +++EL LG L FL K+ L L +++ +Q+S +
Sbjct: 325 MKKMDHMHIVRLIGLCEGETMMLVLELAKLGPLNKFLPKNKH-LPLWNILELMWQVSQGM 149
Query: 535 AYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYM-EDSTYYKASKG 582
YLE+ +FVHRD+AARN+L+ K+ DFG+S+ + ++ YY A +
Sbjct: 148 EYLEANKFVHRDLAARNILLCDEHFAKISDFGMSKTLSRENNYYMAQEA 2
>22005
Length = 873
Score = 95.9 bits (237), Expect = 7e-20, Method: Compositional matrix adjust.
Identities = 77/246 (31%), Positives = 117/246 (47%), Gaps = 55/246 (22%)
Frame = +1
Query: 426 RCIGEGQFGDVHQ----------GIYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTM 475
R IG+G FG V + G + + P L K K S+ ++ F +EA M
Sbjct: 1 RDIGQGAFGRVSKLKFLGLASLVGELIPEKRP*LL*--KMLKEDASEDLQSDFEREASLM 174
Query: 476 RQFDHPHIVKLIGVIT-ENPVWIIMELCTLGELRSFLQV---RKYSL------------- 518
FDHP+IVKL+GV P+ ++ E + G+L FL++ Y+L
Sbjct: 175 ADFDHPNIVKLLGVCAIGKPMCLLFEFMSKGDLNDFLRLCSPENYNLPVSRSQNLVVDLE 354
Query: 519 ---------------------DLASLI-----LY-AYQLSTALAYLESKRFVHRDIAARN 551
D + ++ LY + Q+S +AYL K +VHRD+A R
Sbjct: 355 DGLRVEVEAEECEKDTQSEDRDCSGMLXTKDQLYISQQISAGMAYLAQKDYVHRDLATRT 534
Query: 552 VLVSSNDCVKLGDFGLSRYMEDSTYYKAS-KGKLPIKWMAPESINFRRFTSASDVWMFGV 610
V + + DFGL+R + YY+ S + +PI+WM E+I + +F++ SDVW FGV
Sbjct: 535 VXSRTT*-S*ISDFGLARSVHSVDYYRGSEQDAIPIRWMPLEAILYSKFSTQSDVWSFGV 711
Query: 611 CMWEIL 616
+WEIL
Sbjct: 712 VLWEIL 729
>18921
Length = 697
Score = 95.5 bits (236), Expect = 8e-20, Method: Compositional matrix adjust.
Identities = 68/232 (29%), Positives = 114/232 (49%), Gaps = 4/232 (1%)
Frame = +2
Query: 424 LGRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHI 483
LG+ +GEG +G V + ++ LA+ K D+ ++ ++E M+Q D +I
Sbjct: 44 LGK-LGEGSYGSVFKSLHKE-TGQVLAI-----KQVPVDTDLQEIIKEISIMQQCDSKYI 202
Query: 484 VKLIGVITENP-VWIIMELCTLGELRSFLQVRKYSL---DLASLILYAYQLSTALAYLES 539
VK G +N +WI+ME C G + +++R +L ++A+++ Y + L YL S
Sbjct: 203 VKYYGSYFKNTDLWIVMEYCGAGSVSDIMRLRNKTLVEREIATILYYTLK---GLXYLHS 373
Query: 540 KRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRF 599
+R +HRDI A N+L+++ KL DFG++ + D+ + + P WMAPE I +
Sbjct: 374 RRKIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTPY-WMAPEVIQEIGY 550
Query: 600 TSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTL 651
+D+W G+ E + G P I G+ P N PP L
Sbjct: 551 DCVADIWSLGITALE-MAEGKPPVMETS-------IL*GQSS*FPTNAPPPL 682
>17253
Length = 483
Score = 94.7 bits (234), Expect = 1e-19, Method: Composition-based stats.
Identities = 55/153 (35%), Positives = 88/153 (57%), Gaps = 15/153 (9%)
Frame = -1
Query: 451 VAIKTCKNCTSDSVREKFLQEALTMRQFD-HPHIVKLIGVIT-ENPVWIIMELCTLGELR 508
VA+KT +D+ + +FL+E MR+ HP++V +G T +P I+ME C G+L
Sbjct: 459 VAVKTHNEAATDAEKSEFLRELSIMRKLPRHPNVVSFMGCCTMSDPALILMEFCCHGDLL 280
Query: 509 SFLQVRK---------YSLDLASLILYAYQLSTA--LAYLESKRFVHRDIAARNVLVSSN 557
SFL+ R+ + DL + +++ L A +A++ + + VHRD+AARNVL+S
Sbjct: 279 SFLRKRRPDRTVFLTSTANDLTARDFFSFALHVARGMAHVANNKIVHRDVAARNVLISER 100
Query: 558 DCVKLGDFGLSRYMEDS--TYYKASKGKLPIKW 588
+ K+ DFGLSR + D Y S+ LP++W
Sbjct: 99 NVCKVSDFGLSRRVGDQNDVYEIVSRRPLPLRW 1
>17637
Length = 447
Score = 89.0 bits (219), Expect = 9e-18, Method: Compositional matrix adjust.
Identities = 45/127 (35%), Positives = 69/127 (54%), Gaps = 1/127 (0%)
Frame = +1
Query: 551 NVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKL-PIKWMAPESINFRRFTSASDVWMFG 609
N ++ VKL D LSR + Y G+ PIKW++ E++ + SDVW FG
Sbjct: 1 NCVIDDQLRVKLTDSALSRDLFSGDYNCLGDGEYRPIKWLSLEALQKSHYNEGSDVWSFG 180
Query: 610 VCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRF 669
V MWE+ G P+ + ++ +++G RL P NCP L+++M CWA P+ RP F
Sbjct: 181 VLMWEMCTLGKLPYAEIDPYEMEHYLKDGYRLAQPFNCPDELFTIMAYCWASMPAERPSF 360
Query: 670 TELKAQL 676
++L+ L
Sbjct: 361 SQLQICL 381
>00300
Length = 2318
Score = 88.6 bits (218), Expect = 1e-17, Method: Compositional matrix adjust.
Identities = 74/276 (26%), Positives = 122/276 (44%), Gaps = 13/276 (4%)
Frame = -1
Query: 410 PSTRDYEIQRERIEL----GRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSD--S 463
P DY I R+ G IGEGQFG V+ + MS +A+K K +D
Sbjct: 1700 PREPDYRINVRRVNFRWQRGNKIGEGQFGKVYTAVNMST---GELMALKEMKFQPNDLQQ 1530
Query: 464 VREKFLQEALTMRQFDHPHIVKLIGV-ITENPVWIIMELCTLGELRSFLQVRKYSLDLAS 522
+RE E H ++VK GV + ++ + + ME C G + + K L
Sbjct: 1529 LRE-MCDEIKIFEGIQHENLVKYYGVEVHKDEMLMFMEYCDTGTIE---EAAKMGLPEYL 1362
Query: 523 LILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKG 582
+ Y ++ A+ +L VHRDI N+ ++SN VKLGDFG S ++ T
Sbjct: 1361 IRRYTREIVLAVNHLHENSIVHRDIKGANIFLTSNGHVKLGDFGCSVKLKSHTTMPGEFH 1182
Query: 583 KL--PIKWMAPESINFRR---FTSASDVWMFGVCMWEILMHGVKPFQGVKNN-DVIGRIE 636
L +MAPE + A+D+W G + E+ G +P+ + NN ++ ++
Sbjct: 1181 NLVGTTAYMAPEVFTQNDQGGYGRAADIWSLGCVVIEMAT-GKRPWHDLDNNYQIMYKVG 1005
Query: 637 NGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTEL 672
G + +P + + +DP++R ++L
Sbjct: 1004 IGHKPAVPDSLSVEGKHFLDLIMCHDPAQRALASQL 897
>01718
Length = 959
Score = 86.3 bits (212), Expect = 5e-17, Method: Compositional matrix adjust.
Identities = 70/259 (27%), Positives = 107/259 (41%), Gaps = 14/259 (5%)
Frame = +3
Query: 428 IGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLI 487
IG G F +V + + + + K T S R L+E + + H +I++ +
Sbjct: 171 IGAGFFSEVFKVTH------RITGQVMALKMNTMTSNRHNMLREVQLLNRLQHANILRFM 332
Query: 488 GV-ITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRD 546
GV + E + + E G L L+ + L I L+ L YL S RF+HRD
Sbjct: 333 GVCVHEGQLHALTEYIPSGNLEQLLEKKDEELPWTQRIQLTLGLARGLDYLHSTRFIHRD 512
Query: 547 IAARNVLVSSNDC----VKLGDFGLSRYMEDSTYYKASKGKLPIK----WMAPESINFRR 598
+ ++N+L+ D + DFGL+ + D K KLP WMAPE +N
Sbjct: 513 LTSKNILIRREDNHGYHAVIADFGLATKIPDPL----DKEKLPTVGSPYWMAPEVLNGHF 680
Query: 599 FTSASDVWMFGVCMWEILMH-----GVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYS 653
+ +D++ G+ M EI + P D + E M CP
Sbjct: 681 YNERADLFSVGIIMCEITARIPADPDIMPRMNNFGVDYVALSE------MISYCPLDYLQ 842
Query: 654 LMTKCWAYDPSRRPRFTEL 672
L KC DP +RPR E+
Sbjct: 843 LAFKCCQVDPQKRPRGVEI 899
>13305
Length = 549
Score = 82.4 bits (202), Expect = 8e-16, Method: Compositional matrix adjust.
Identities = 36/97 (37%), Positives = 55/97 (56%)
Frame = +2
Query: 583 KLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLP 642
++PI+WMA ES+ +T+ SDVW FGV +WEI G P+ + +++G RL
Sbjct: 8 RVPIRWMAVESLFNNTYTTQSDVWSFGVVLWEIFTLGGTPYSSTDTQQLFAFLKDGYRLK 187
Query: 643 MPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLRTL 679
P C Y++M +CW + RRP F EL +L+ +
Sbjct: 188 RPKLCDQNTYAMMLQCWNENAQRRPTFPELCGRLQRM 298
>19301
Length = 712
Score = 82.0 bits (201), Expect = 9e-16, Method: Compositional matrix adjust.
Identities = 54/170 (31%), Positives = 87/170 (51%), Gaps = 1/170 (0%)
Frame = +2
Query: 400 IIDEEDTYTMPSTRDYEIQRERIELGRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNC 459
II + + D+EI E I +G G G V G + E VA+K ++
Sbjct: 245 IIGKAAAAELKQQDDWEIPFESITDLEWLGSGAQGAVFLGKLCAEE-----VAVKKVRDI 409
Query: 460 TSDSVREKFLQEALTMRQFDHPHIVKLIGVITENPVW-IIMELCTLGELRSFLQVRKYSL 518
+R +R+ +HP+I+ GV T+ P + IIME C G+L L+ K +
Sbjct: 410 KETDIR--------NLRKLNHPNIISFKGVCTQAPCYCIIMEYCPYGQLYEVLRDGK-EI 562
Query: 519 DLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLS 568
A ++ ++ Q+++ + YL S + +HRD+ + NVLV+ ND VK+ DFG S
Sbjct: 563 PPALVLDWSKQIASGMNYLHSHKIIHRDLKSPNVLVAKNDVVKISDFGTS 712
>12721
Length = 821
Score = 78.2 bits (191), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 66/247 (26%), Positives = 103/247 (41%), Gaps = 8/247 (3%)
Frame = +1
Query: 428 IGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLI 487
IGEG G V I S + +AV + RE E + MR + HP+IV++
Sbjct: 112 IGEGSTGIV--CIATSRDGRQMAVKKMDLRK---QQRRELLFNEVVVMRDYHHPNIVEMY 276
Query: 488 G-VITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRD 546
+ + +W++ME G L V +D + ALA+L + +HRD
Sbjct: 277 NSYLVNDELWVVMEFMEGGALTDI--VTNNRMDEVQIATVCRACLKALAFLHANGVIHRD 450
Query: 547 IAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVW 606
I + ++L+S + VKL DFG + + S P WMAPE I+ + D+W
Sbjct: 451 IKSDSILLSHDGKVKLXDFGFCAQVTQDLQKRKSLVGTPY-WMAPEVISRLPYGPEVDIW 627
Query: 607 MFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPP-------NCPPTLYSLMTKCW 659
G+ + E ++ PF + RI + MPP P L + +
Sbjct: 628 SLGIMVME-MIDAEPPFFNEPPLQAMRRIRD-----MPPPKLRNTHKISPRLQGFIDRML 789
Query: 660 AYDPSRR 666
DP +R
Sbjct: 790 VRDPHQR 810
>14420
Length = 528
Score = 75.5 bits (184), Expect = 8e-14, Method: Compositional matrix adjust.
Identities = 45/167 (26%), Positives = 78/167 (46%), Gaps = 1/167 (0%)
Frame = +2
Query: 458 NCTSDSVREKFLQEALTMRQFDHPHIVK-LIGVITENPVWIIMELCTLGELRSFLQVRKY 516
N + +E + E L MR+ +P+IV L + +W++ME G L V +
Sbjct: 11 NLSQQPKKELIINEILVMRENQNPNIVNYLDSYLVGEELWVVMEFLAGGSLTDV--VTET 184
Query: 517 SLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTY 576
+D + + AL +L + +HRDI + N+L+ + VKL DFG +
Sbjct: 185 CMDEGQIAAVCRECLQALEFLHENQVIHRDIKSDNILLGMDGSVKLTDFGFCAQLSPEQS 364
Query: 577 YKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPF 623
+++ P WMAPE + +++ D+W GV E ++ G P+
Sbjct: 365 KRSTMVGTP-YWMAPEVVTRKQYGPTVDIWSLGVMCIE-MIEGEPPY 499
>13592
Length = 980
Score = 74.7 bits (182), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 67/257 (26%), Positives = 118/257 (45%), Gaps = 9/257 (3%)
Frame = +2
Query: 428 IGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEAL-TMRQFDHPHIVKL 486
IG+G+FG V+ + N +A+K ++ K + E L + H ++V+
Sbjct: 8 IGQGRFGKVYTAV---NNNTGELMAMKEIAIQPGETRALKNVAEELKILEGIKHKNLVRY 178
Query: 487 IGV-ITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHR 545
G+ + + I MELC+ G L S +++ L A + QL + +A L VHR
Sbjct: 179 YGIEVHREELLIFMELCSEGTLESLVELTG-GLPEALSRRFTAQLLSGVAELHKHGIVHR 355
Query: 546 DIAARNV-LVSSNDCVKLGDFGLSRYMEDSTYYKAS-KGKLPIK-WMAPE---SINFRRF 599
DI N+ LV ++ +KLGDFG + ++ T +G + + +MAPE N
Sbjct: 356 DIKTANIFLVDGSNSLKLGDFGSAVKIQAHTTVPGELQGYVGTQAYMAPEVFTKTNSDGH 535
Query: 600 TSASDVWMFGVCMWEILMHGVKPFQGVKNN-DVIGRIENGERLPMPPNCPPTLYSLMTKC 658
+D+W G + E + G +P+ +N ++ ++ GE+ P + + + C
Sbjct: 536 GRLADIWSVGCVVVE-MASGKRPWAQFDSNFQIMFKVGMGEKPQAPESLSQEGHDFIDHC 712
Query: 659 WAYDPSRRPRFTELKAQ 675
+DP +R EL Q
Sbjct: 713 LQHDPKQRLSAIELLEQ 763
>27546
Length = 426
Score = 70.1 bits (170), Expect = 4e-12, Method: Composition-based stats.
Identities = 35/114 (30%), Positives = 65/114 (57%), Gaps = 1/114 (0%)
Frame = -1
Query: 462 DSVREKFLQEALTMRQFDHPHIVKLIGVITENP-VWIIMELCTLGELRSFLQVRKYSLDL 520
D V++ F +E + + DHP+I+++ ++ P ++I M G++ S ++ + +D
Sbjct: 357 DFVKKFFPRELEILTRLDHPNIIQIHSILQRGPKIFIFMRYAEKGDMLSHIK-KTGPIDE 181
Query: 521 ASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDS 574
A ++ +Q++ AL YL S HRD+ N+L+S VK+ DFG +RY D+
Sbjct: 180 AQTKVWFFQMAKALQYLHSHDIAHRDLKCENILLSKRLNVKIADFGFARYCRDA 19
>30755
Length = 1137
Score = 70.1 bits (170), Expect = 4e-12, Method: Compositional matrix adjust.
Identities = 52/190 (27%), Positives = 95/190 (50%), Gaps = 1/190 (0%)
Frame = +2
Query: 525 LYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKL 584
Y ++ +AL YL S+ ++RD+ N+L+ + +K+ DFGL + ED TY + +K
Sbjct: 44 FYGAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCK--EDITYGRTTKTFC 217
Query: 585 PI-KWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPM 643
+++APE ++ + A D W GV M+E++ G PF +++DV+ + E +
Sbjct: 218 GTPEYLAPEVLDDNDYGRAVDWWGTGVVMYEMIC-GRLPFYN-RDHDVLFTLILVEDVKF 391
Query: 644 PPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLRTLQYWTCEGLGKCCQPIWKSVSDSNR 703
P N SL++ A DP R R + ++ +Q P + S++ ++
Sbjct: 392 PRNITDEAKSLLSGLLAKDP--RNRLGGGQDDVKEIQ----------AHPFFASINWTDL 535
Query: 704 KWKKISAGWK 713
KKI+ +K
Sbjct: 536 VQKKITPPFK 565
>31885
Length = 529
Score = 68.6 bits (166), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 46/148 (31%), Positives = 77/148 (52%), Gaps = 6/148 (4%)
Frame = -2
Query: 475 MRQFDHPHIVKL-IGVITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTA 533
+ + DHP +V L E ++++++L G+LR +Q ++ S + Y QL+
Sbjct: 510 LTRLDHPFLVNLWYAFQDEEDLFMVVDLFLGGDLRYHMQ-QEVSFREDCVKFYLCQLALV 334
Query: 534 LAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPE- 592
L YL S++ VHRDI N+L+ + DF ++ +ED ++ G P +MAPE
Sbjct: 333 LDYLRSQKIVHRDIKPDNILLDEQGHCHVTDFNIATQLEDDELATSTSGTRP--YMAPEV 160
Query: 593 ---SINFRR-FTSASDVWMFGVCMWEIL 616
+IN RR + D W GV ++E+L
Sbjct: 159 YGVAINERRGYGFPVDWWSLGVSLFELL 76
>09606
Length = 1300
Score = 68.2 bits (165), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 71/305 (23%), Positives = 121/305 (39%), Gaps = 39/305 (12%)
Frame = -3
Query: 428 IGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLI 487
+G+G+ +++G N I+ CK R + HP++V+
Sbjct: 1091 LGKGEHSIIYKGRRKGTINFVAIHCIEKCK-------RPEVTNTVRMTHDISHPNVVQFH 933
Query: 488 G-VITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRD 546
T N +W+++ELCT G L L + + L S+ + L T L Y+ S + D
Sbjct: 932 EWYETSNHLWLVVELCTGGSLADIL-AQDHHLPETSIRDFGIHLVTGLHYIHSLGILFHD 756
Query: 547 IAARNVLVSSNDCVKLGDFGLSRY----MEDSTYYKASKG-------------KLPIK-- 587
+ VL+ ++ +K DFGLS+ +E+ + A G ++P
Sbjct: 755 LRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQWNIQSAEEMMKQVPTSGS 576
Query: 588 --WMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIEN-------- 637
+MAPE + SD+W G +E + G PF G + ++ N
Sbjct: 575 PTYMAPEVFQGAEPSIMSDLWALGCVFYE-MFSGHPPFLGETYDITKDKVLNKEFPLPKV 399
Query: 638 -GERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTEL------KAQLRTL--QYWTCEGLG 688
G RL P+ P +L+ D +RR + L + L +L ++ E +G
Sbjct: 398 KGSRLSAKPS--PEFLNLLESLLQKDSTRRLSWASLVKHAFWQGGLSSLVKEFTMSEEIG 225
Query: 689 KCCQP 693
C P
Sbjct: 224 GHCHP 210
>00715
Length = 1788
Score = 67.8 bits (164), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 59/253 (23%), Positives = 110/253 (43%), Gaps = 34/253 (13%)
Frame = +1
Query: 449 LAVAIKTCKNCTSDSVREKFLQEALTMR-QFDHPHIVKLIGVIT----ENPVWIIMELCT 503
+AV I ++ ++R+ + E L R H ++V ++G + E+ W+ ME
Sbjct: 7 VAVKIYHKRSSNPRALRQSYSNELLAFRCGLRHVNVVSILGATSLHRFEDGAWLAMEYVG 186
Query: 504 LGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLG 563
L++ L + +D + + A Q++ L YL S VH D+ N L++ + +++
Sbjct: 187 PLNLQTILNDHQQDIDSSMRLSLALQMARGLHYLHSINIVHLDLKPANCLLTRDLKLRIA 366
Query: 564 DFGL-------------------SRYMEDSTYYKASKGKLP--IKWMAPESINFRRFTSA 602
DFG +E + A K +L + + APE + + +
Sbjct: 367 DFGCCHQLTPTGLDMGEREGGMAGNELELTPVQGAWKNELAGTLAYRAPELLKGLQPSVR 546
Query: 603 SDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPT--------LYSL 654
SDV+ G+ +W++ P++GV + V+ ++ + + P PP P T L
Sbjct: 547 SDVYSLGITLWQMCTRQ-GPYEGVPAHAVVYQVVSKDLRPCPP--PSTEDDPFEVMFRDL 717
Query: 655 MTKCWAYDPSRRP 667
T+CWA RP
Sbjct: 718 YTQCWARRVEDRP 756
>07833
Length = 1504
Score = 67.4 bits (163), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 54/225 (24%), Positives = 103/225 (45%), Gaps = 7/225 (3%)
Frame = -3
Query: 464 VREKFLQEALTMRQFDHPHIVKLIGVITENP-VWIIMELCTLGELRSFLQVRK-YSLDLA 521
+ F++E +R F+HP+++ ++ + P + +I + G L + L +D
Sbjct: 1490 ITRDFMEEFPRLRIFNHPNVLPVLACCNQPPNLVLISQFMPFGSLYNTLHGESGIVVDQN 1311
Query: 522 SLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASK 581
+ +A ++ + +L S + N L++S + D M D + K
Sbjct: 1310 QSLRFAMDIARGMEFLHSM-----EPTIPNFLLTSKHVMIDEDLTARINMADYCFSFHEK 1146
Query: 582 GKL-PIKWMAPESINFRR---FTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIE- 636
GK+ WMAPE++ R T A+D+W F + MWE+ V PF + + +V ++
Sbjct: 1145 GKVYSPAWMAPEALQRRPDDINTRAADMWSFAILMWELETREV-PFAELSSMEVGMKVAL 969
Query: 637 NGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLRTLQY 681
G R+ +PP + L+ C +P +RPRF + L +++
Sbjct: 968 EGLRISIPPGISLHMSRLIKICMNEEPGKRPRFDMIIPILEKMKH 834
>13066
Length = 551
Score = 67.0 bits (162), Expect = 3e-11, Method: Compositional matrix adjust.
Identities = 49/174 (28%), Positives = 82/174 (47%), Gaps = 10/174 (5%)
Frame = +3
Query: 446 NPALAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITENPV-WIIMELCTL 504
N LA I + D V + F +E + + DHP+I+++ ++ P +I M
Sbjct: 51 NIKLACKIIDKEKAPVDFVEKFFPRELDLLTKLDHPYIIQIHSILQRXPKNFIFMRFAER 230
Query: 505 GELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGD 564
G+L +++Q + + + I + YQ++TAL YL S HRD+ N+L+SS+ VKL D
Sbjct: 231 GDLLTYIQEVGFVKEKQAKIWF-YQMTTALNYLHSYDVAHRDLKCENILLSSHFNVKLAD 407
Query: 565 FGLS---------RYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFG 609
FG + +YM + A+ I + AP + +D W G
Sbjct: 408 FGFACACITESGEKYMSRTYCGSAAYAAPEIVYGAPYA------PKVADAWSLG 551
>14126
Length = 1265
Score = 64.3 bits (155), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 72/296 (24%), Positives = 135/296 (45%), Gaps = 19/296 (6%)
Frame = +3
Query: 369 ALPSIPKLANSEKQGMRTH-AVSVSETDDYAEIIDEEDTYTMPSTRDYEIQRERIELGRC 427
ALP+I ++ +E+ +T AV +T + D + +R + ++ E
Sbjct: 33 ALPTIFRIC*NEESSPKTSPAVRSMKTAISPKGRDGQSESAAKMSRRRDSTEQKYEEVAV 212
Query: 428 IGEGQFGDVHQGIYMSPENPALAVAIKTCK-NCTSDSVREKFLQEALTMRQ---FDHPHI 483
IG G +G V++ + N VA+K + N T + + ++E ++Q ++HP++
Sbjct: 213 IGNGAYGTVYKARDL--RNQGEFVAMKRIRLNNTEEGMPMMAIREISMLKQLEQYEHPNV 386
Query: 484 VKLIGVITENPVWIIMELCTLGELRSFLQVRKYSLDLASLIL--------------YAYQ 529
V+L+ V + N + T E+R L DLA+ + Q
Sbjct: 387 VRLLDV-SHNTI-------TDREIRLNLVFEYIEHDLATYLAKCPSPGLGPDRIKDLMLQ 542
Query: 530 LSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWM 589
L + +L S R VHRD+ +N+L+S + +KL DFGL+R S + + + + +
Sbjct: 543 LLNGVDFLHSNRIVHRDLKPQNLLISKDGRLKLADFGLARIY--SFHMALTTVVVTLWYR 716
Query: 590 APESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPP 645
+PE + + ++ D+W G C++ L F+G D + +I E + +PP
Sbjct: 717 SPEVLMQAEYGTSVDIWSCG-CIFAELFTRRALFKGSSEFDQLKKI--FEVIGLPP 875
>01060
Length = 1800
Score = 63.9 bits (154), Expect = 3e-10, Method: Compositional matrix adjust.
Identities = 54/228 (23%), Positives = 112/228 (49%), Gaps = 6/228 (2%)
Frame = +1
Query: 414 DYEIQRERIELGRCIGEGQFGDVHQGIYMSPENPALAVAIKTCK-NCTSDSVREKFLQEA 472
D+E + + IGEG +G V++ + + +A+K + + D V ++E
Sbjct: 55 DFETALSDLTDFQKIGEGTYGVVYKCRHRATGR---KLAMKKIRLRGSEDGVPSSAIREI 225
Query: 473 LTMRQFDHPHIVKLIGVITENP-VWIIMELCTLGELRSFLQV--RKYSLDLASLILYAYQ 529
+R+ H +IV L VI E+ ++++ E ++ +L+ ++ LD + Y +Q
Sbjct: 226 AMLRELRHTNIVCLEDVIMEDERLFLVFEFLSM-DLKMYIDKFPEGVVLDRRLVKSYVFQ 402
Query: 530 LSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWM 589
+ T + + +R VHRD+ +N+L++ +K+ DFG++R + +A ++ W
Sbjct: 403 IVTGIXFCHQRRIVHRDLKPQNLLINHTGAIKIADFGMARTF--ALPVRAYTHEVVTLWY 576
Query: 590 -APESI-NFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRI 635
APE + ++++ DVW G ++L+ F+G D + +I
Sbjct: 577 RAPEILMGASKYSTPVDVWSIGTIFADMLIR-TPIFKGDSEIDQLFKI 717
>13212
Length = 1067
Score = 61.6 bits (148), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 51/196 (26%), Positives = 84/196 (42%), Gaps = 18/196 (9%)
Frame = -1
Query: 495 VWIIMELCTL---GELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARN 551
VW I+++ + G L S + + + A + +++ AL +L +HRDI A N
Sbjct: 1067 VWXIVDVFRVLWWGALDSIMVDLEKPMTEAQICYVCHEMCMALDFLHRHHVIHRDIKAGN 888
Query: 552 VLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAP-----ESINFRRFTSASDVW 606
VL++ + VKL DFG+S + + + P WMAP E++ + +D+W
Sbjct: 887 VLLTIDGEVKLADFGVSAKNTQTQQKRDTFIGTPY-WMAPEVVLCETLKDTPYDFKADIW 711
Query: 607 MFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTL----------YSLMT 656
GV + E P + + V+ +I + PPTL +
Sbjct: 710 SLGVTLIE-FAQIEPPNKEMHPMRVLIKIHKSD--------PPTLEKPKKWTKLFKDFIA 558
Query: 657 KCWAYDPSRRPRFTEL 672
KC DP+ RP EL
Sbjct: 557 KCLVKDPNLRPTAAEL 510
>19094
Length = 898
Score = 61.6 bits (148), Expect = 1e-09, Method: Composition-based stats.
Identities = 34/114 (29%), Positives = 62/114 (54%), Gaps = 3/114 (2%)
Frame = +1
Query: 505 GELRSFLQVRKYSL---DLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVK 561
G + +++R +L ++A+++ Y + L YL S+R +HRDI A N+L+++ K
Sbjct: 10 GSVSDIMRLRNKTLVEREIATILYYTLK---GL*YLHSRRKIHRDIKAGNILLNNEGHAK 180
Query: 562 LGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEI 615
L DFG++ + D+ + + P WMAPE I + +D+W G+ E+
Sbjct: 181 LADFGVAGQLTDTMAKRNTVIGTPY-WMAPEVIQEIGYDCVADIWSLGITALEM 339
>29581
Length = 1278
Score = 60.8 bits (146), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 49/163 (30%), Positives = 78/163 (47%), Gaps = 8/163 (4%)
Frame = -2
Query: 464 VREKFLQEALTMRQFDHPHIVKLIGVI---TENPVWIIMELCTLGELRSFLQVRKYSLDL 520
VR FL L +R H +IV+L V+ + + ++++ME C +L S L
Sbjct: 1208 VRSTFL---LNLR---HQNIVQLQEVVVGKSLDSLFLVMEYCE-QDLASLLDNMPAPFSE 1050
Query: 521 ASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKAS 580
+ + QL L YL +HRD+ N+L++ CVK+ DFGL+R Y K
Sbjct: 1049 SQVKCIVLQLLKGLRYLHEAFIIHRDLKVSNLLMTDKGCVKIADFGLAR-----NYGKPQ 885
Query: 581 KGKLP----IKWMAPESI-NFRRFTSASDVWMFGVCMWEILMH 618
K P + + APE + + ++A D+W G + E+L H
Sbjct: 884 KPMTPKVVTLWYRAPELLFGSKTHSTAIDMWSAGCILGELLGH 756
>01756
Length = 1858
Score = 59.7 bits (143), Expect = 5e-09, Method: Compositional matrix adjust.
Identities = 47/204 (23%), Positives = 86/204 (42%), Gaps = 16/204 (7%)
Frame = -3
Query: 428 IGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKF----LQEALTMRQFDHPHI 483
IG+G FG+V + + + K D+ +E F L+E ++ +H ++
Sbjct: 1718 IGQGTFGEVFKARCKKTKQ------VVAMKKVLMDNEKEGFPITALREIKILQLLNHENV 1557
Query: 484 VKLIGVITENPV---------WIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTAL 534
V LI + + +++ E C +L L +L + QL L
Sbjct: 1556 VDLIEICSTKATSANRYKSMFYLVFEFCE-HDLAGLLSNMSVVFNLPEIKEVMKQLMNGL 1380
Query: 535 AYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSR-YMEDSTYYKASKGKLPIKWMAPES 593
Y+ + +HRD+ A N+L++ +KL DFGL+R + + ++ W P
Sbjct: 1379 YYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRPPE 1200
Query: 594 INF--RRFTSASDVWMFGVCMWEI 615
+ R +++A D W G M E+
Sbjct: 1199 LLLGDRNYSTAIDQWGAGCIMAEM 1128
>19761
Length = 473
Score = 58.9 bits (141), Expect = 9e-09, Method: Compositional matrix adjust.
Identities = 34/130 (26%), Positives = 67/130 (51%), Gaps = 8/130 (6%)
Frame = -3
Query: 523 LILYAYQLSTALAYLESKR--FVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKAS 580
++ + Q ++AL Y+ + +HRD+ +N+ V+ V+LGD GL+R + + S
Sbjct: 417 IVCWLMQTASALNYMHTHTPVILHRDLKPQNIYVTEKGDVRLGDLGLARKLTGPADFATS 238
Query: 581 KGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIG------R 634
+ I +++PE ++ + + S SD+W G ++I G K +D +G +
Sbjct: 237 QVG-TIMYLSPEILSQQPYNSKSDIWSLGCVFYDI--------TGKKGSDEMGVMFLLVQ 85
Query: 635 IENGERLPMP 644
+ G +LP+P
Sbjct: 84 VMGGRKLPLP 55
>04591
Length = 1117
Score = 58.5 bits (140), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 46/167 (27%), Positives = 75/167 (44%), Gaps = 16/167 (9%)
Frame = -2
Query: 469 LQEALTMRQFDHPHIVKLIGVIT---------ENPVWIIMELCTLGELRSFLQVRKYSLD 519
L+E ++Q +H ++V+L + ++ ++I E C +L L +
Sbjct: 1077 LREIKILQQLEHENVVQLQEICHTQAGPYNRYKSTFYLIFEYCDY-DLAGLLNNLRVKFS 901
Query: 520 LASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKA 579
LA QL L Y+ +K+ +HRDI A N+L++ + +KL DFGLSR S K
Sbjct: 900 LADKKNLMSQLLNGLFYIHTKQILHRDIKAANILLTRDGVLKLADFGLSRPWVKS---KR 730
Query: 580 SKGKLPIKWMAPESINF--RRFTSASDVWMFGVCMWEI-----LMHG 619
++ W P + R + D+W G M E+ LM G
Sbjct: 729 LTNRVVTLWYRPPELLLGEREYGPEIDMWGVGCIMAEMWSRKPLMQG 589
>21079
Length = 878
Score = 57.8 bits (138), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 34/128 (26%), Positives = 66/128 (51%), Gaps = 2/128 (1%)
Frame = +1
Query: 497 IIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSS 556
++ME GEL + + L + + Q+ + + Y+ ++ +H D+ NVL S
Sbjct: 55 LVMEFVGAGELFERVIRDDFVLTERDCVHFVRQICSGVGYMHTQSILHLDLKPENVLCVS 234
Query: 557 NDC--VKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWE 614
++ +K+ DFGL+R+ + + G P +++APE +N+ +D+W GV +
Sbjct: 235 DNSNQIKIIDFGLARFYKPGDSLQVLFGT-P-EFIAPEVVNYDEINFTTDMWSIGVICY- 405
Query: 615 ILMHGVKP 622
IL+ G+ P
Sbjct: 406 ILLSGLSP 429
>01707
Length = 757
Score = 55.8 bits (133), Expect = 8e-08, Method: Compositional matrix adjust.
Identities = 53/199 (26%), Positives = 90/199 (45%), Gaps = 10/199 (5%)
Frame = +1
Query: 428 IGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKF-LQEALTMRQFDHPHIVKL 486
IGEG +G V + + + VAIK D + +K ++E ++Q HP++V+L
Sbjct: 88 IGEGSYGVVFK---CRNKETSQLVAIKKFVESEDDPLIKKIAMREIRMLKQLKHPNLVRL 258
Query: 487 IGVITENP----VWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRF 542
I V V+ ++ L EL + R + I+Y Q A+ +
Sbjct: 259 IEVFRRKKRLHLVFDYVDHTLLNELDRY--PRGLPEPMVKRIIY--QTLLAVNFCHQYNT 426
Query: 543 VHRDIAARNVLVSSNDCVKLGDFGLSRYM----EDSTYYKASKGKLPIKWMAPE-SINFR 597
+HRD+ N+L++ VKL DFG +R + ++ T Y A++ + APE +
Sbjct: 427 IHRDVKPENILITRQGQVKLCDFGFARILTGPGDEYTDYVATRW-----YRAPELLVGDT 591
Query: 598 RFTSASDVWMFGVCMWEIL 616
++ DVW G E+L
Sbjct: 592 QYGPPVDVWAIGCVFAELL 648
>18484
Length = 635
Score = 55.8 bits (133), Expect = 8e-08, Method: Compositional matrix adjust.
Identities = 28/113 (24%), Positives = 59/113 (52%)
Frame = +1
Query: 525 LYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKL 584
YA +++ L +L + ++RD+ NV++ S +K+ DFG+ + +
Sbjct: 55 FYAAEIAVGLFFLHDQGIIYRDLKLDNVMLDSEGHIKIADFGMCKEGMTGDATTRTFCGT 234
Query: 585 PIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIEN 637
P ++APE + ++ ++ + D W +GV ++E+L G PF G +++ I +
Sbjct: 235 P-DYIAPEIVLYQPYSKSVDWWAYGVLLFEMLA-GQPPFDGEDEDELFSSITD 387
>03240
Length = 1683
Score = 55.5 bits (132), Expect = 9e-08, Method: Compositional matrix adjust.
Identities = 63/263 (23%), Positives = 108/263 (41%), Gaps = 56/263 (21%)
Frame = -3
Query: 417 IQRERIELGRC-------IGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFL 469
I+ +R ++ +C +G G FG+V + + A+KT + SD ++ +
Sbjct: 1321 IRLKRAKMDKCMFEKIKTLGVGAFGEVS---LCRKNDTGMLYAMKTLRK--SDVLKRNQV 1157
Query: 470 QEALTMRQF----DHPHIVKLIGVITE-NPVWIIMELCTLGELRSFLQVRKYSLDLASLI 524
R D+ +VKL + N ++ +M+ G+L L +R LD
Sbjct: 1156 AHVKAERDILAEADNEWVVKLYYSFQDHNYLYFVMDYVPGGDLMGLL-IRMEILDEPLAR 980
Query: 525 LYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLS---RYMEDSTYYK--- 578
Y +L A+ + F+HRDI N+L+ N +KL DFGL R+ +S YY+
Sbjct: 979 FYVAELVQAIESVHRMGFIHRDIKPDNILIDRNGHIKLTDFGLCTGFRWTHNSKYYQRDG 800
Query: 579 --ASKGKLPIK-----------------------------------WMAPESIN-FRRFT 600
A + + +K ++APE ++ +T
Sbjct: 799 THARQDSMEVKCQLDEQCQCEILKPLERRRKREQRCLAHSLVGTPNYIAPEVLSRLGGYT 620
Query: 601 SASDVWMFGVCMWEILMHGVKPF 623
S D W GV ++E+L+ G PF
Sbjct: 619 SVCDWWSVGVILFEMLV-GHPPF 554
>01966
Length = 1735
Score = 55.5 bits (132), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 30/113 (26%), Positives = 62/113 (54%), Gaps = 3/113 (2%)
Frame = -1
Query: 460 TSDSVREKFLQEALTMRQFDHPHIVKLIGVITENP-VWIIMELCTLGELRSFLQV--RKY 516
+ D V ++E +R+ H +IV L VI E+ ++++ E ++ +L+ ++
Sbjct: 1597 SEDGVPSSAIREIAMLRELRHTNIVCLEDVIMEDERLFLVFEFLSM-DLKMYIDKFPEGV 1421
Query: 517 SLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSR 569
LD + Y +Q+ T + + +R VHRD+ +N+L++ +K+ DFG++R
Sbjct: 1420 VLDRRLVKSYVFQIVTGINFCHQRRIVHRDLKPQNLLINHTGAIKIADFGMAR 1262
>07836
Length = 1478
Score = 55.1 bits (131), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 70/283 (24%), Positives = 119/283 (42%), Gaps = 55/283 (19%)
Frame = -1
Query: 465 REKFLQEALTMRQFDHPHIVKLI-----GVITENPVWIIMELCTLGELRSFLQVRKYSLD 519
RE L + + +R H +I+ I G + +++I + G L +L R LD
Sbjct: 1424 RETELYQTVLLR---HENILGFIAADIKGTGSWTQLFLITDYHENGSLHDYLLSR--VLD 1260
Query: 520 LASLILYAYQLSTALAYLESKRF--------VHRDIAARNVLVSSNDCVKLGDFGLS-RY 570
+ ++ A+ LA+L + F HRDI ++N+LV N + D GL+ RY
Sbjct: 1259 SSEMLALAHSAICGLAHLHIEIFGTRGKPAIAHRDIKSKNILVKKNGTCCIADLGLAVRY 1080
Query: 571 MEDSTYYKASKG--KLPIKWMAPESI-------NFRRFTSASDVWMFGVCMWEI----LM 617
+ +S + + ++MAPE + NF F A D++ FG+ MWEI ++
Sbjct: 1079 ISESNEVDVAPNPRQGTKRYMAPEVLEMLLNVKNFDAFKQA-DMYAFGLVMWEIARCCVI 903
Query: 618 HGVK-----PFQGVKNND--------VIGRIENGERLPMPPNCPP---TLYSLMTKCWAY 661
GV PF +D V+ + +P+ P + +M +CW+
Sbjct: 902 GGVAEEYQVPFYNCLPHDPSFEDVRLVVSVDKVRPDIPLRWQEDPIMKVMVKVMCECWSG 723
Query: 662 DPSRR---PRFTELKAQLRTLQYWTCEGLG---------KCCQ 692
+P+ R R + +L LQ G+ +CCQ
Sbjct: 722 NPAARLTALRVKKTLGKLSELQATKLSGIKS*SSTSTDHQCCQ 594
>12672
Length = 773
Score = 52.8 bits (125), Expect = 6e-07, Method: Compositional matrix adjust.
Identities = 44/190 (23%), Positives = 74/190 (38%), Gaps = 16/190 (8%)
Frame = +3
Query: 531 STALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGL---SRYMEDSTYYKASKGKLPIK 587
++ + YL VHRDI N+L+ S K+GDF + E T AS
Sbjct: 21 ASGIQYLNDNGHVHRDIKTANILLDSEYTAKVGDFATVVSAPSGEGKTVQNASVVIGTAA 200
Query: 588 WMAPESINFRRFTSASDVWMFGVCMWEILMHGVKP-------------FQGVKNNDVIGR 634
++APE+I+F ++ D + FGV + E++ V + V+ + I
Sbjct: 201 YLAPEAIHF-DVSTKLDSYSFGVVLLEVITGLVAQDYSREERTLSSHIMENVEEPEEIHD 377
Query: 635 IENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLRTLQYWTCEGLGKCCQPI 694
+ P LY + +C +RP +++ +L L + C I
Sbjct: 378 FVDQSAGTWPDGAVDKLYDISMRCLNLSKKQRPNVKDIRPELEEL*GCIVNRVRVIC*NI 557
Query: 695 WKSVSDSNRK 704
W S + K
Sbjct: 558 WDPFSQNGAK 587
>15910
Length = 1361
Score = 52.0 bits (123), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 34/110 (30%), Positives = 56/110 (50%), Gaps = 3/110 (2%)
Frame = +2
Query: 533 ALAYLESKRFVHRDIAARNVL---VSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWM 589
+ Y+ + VHRD+ N+L ++ + +KL DFGLSR +E G P +
Sbjct: 500 GVQYIHANGVVHRDLKPENLLYECMTDDSKLKLADFGLSRIIEPEVQMSTVCGT-P-GYC 673
Query: 590 APESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGE 639
APE + ++T + D+W GV + IL+ G +PF ++ +I GE
Sbjct: 674 APEVLKGDKYTPSVDMWSVGVIAY-ILLCGYEPFFAENEFEMYRKIIKGE 820
>26711
Length = 405
Score = 52.0 bits (123), Expect = 1e-06, Method: Composition-based stats.
Identities = 32/102 (31%), Positives = 58/102 (56%), Gaps = 5/102 (4%)
Frame = -2
Query: 529 QLSTALAYLESKRFVHRDIAARNVLVSSN--DCVKLGDFGLSRYM---EDSTYYKASKGK 583
Q+ L ++ ++ VH D+ N+L+S + D V+L DFGL+R + +++ + G
Sbjct: 392 QVLDILQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARKLYPPQETFLNHGTPG- 216
Query: 584 LPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQG 625
+ +PE+++ + ++ASDVW GV + IL+ G PFQ
Sbjct: 215 ----FTSPEALDVKPISTASDVWGVGVLAY-ILLSGQSPFQA 105
>21433
Length = 590
Score = 48.5 bits (114), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 30/98 (30%), Positives = 49/98 (50%)
Frame = +2
Query: 526 YAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLP 585
Y YQLS+AL Y ++ +HRDI N+L+ +K+ DFG S + S + +
Sbjct: 182 YIYQLSSALEYCHYRKVIHRDIKPENLLLGLKGDLKIADFGWSVHAPSS---RRTTMCGT 352
Query: 586 IKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPF 623
+ ++ PE + + D+W GV +E L+ G P
Sbjct: 353 LDYLPPEMVEGKTHDENVDLWSLGVLCYEFLV-GTPPL 463
>32264
Length = 287
Score = 47.4 bits (111), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 20/45 (44%), Positives = 27/45 (60%)
Frame = +1
Query: 635 IENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLRTL 679
IE+G RL P P ++Y LM +CW Y P +RP F EL L+ +
Sbjct: 1 IEDGYRLQQNPQTPDSVYKLMLRCWEYVPEKRPHFKELYTSLKDI 135
>25550
Length = 941
Score = 46.6 bits (109), Expect = 5e-05, Method: Compositional matrix adjust.
Identities = 24/73 (32%), Positives = 35/73 (47%), Gaps = 1/73 (1%)
Frame = +3
Query: 608 FGVC-MWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRR 666
G C +W++ + GV +V +E G R+ P P +Y LM KCW +DP R
Sbjct: 12 MGACDIWDVX------YPGVDLTEVYHLLERGYRMERPQGTPADVYILMLKCWQWDPKER 173
Query: 667 PRFTELKAQLRTL 679
P F E+ L +
Sbjct: 174 PTFKEIHYLLENM 212
>28157
Length = 400
Score = 46.2 bits (108), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 31/112 (27%), Positives = 54/112 (48%), Gaps = 6/112 (5%)
Frame = +3
Query: 461 SDSVREKFLQEALTMRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVR--KYSL 518
S+ ++ F+QE + + HP+IV L G ++PV ++ME G L + L +
Sbjct: 30 SEQEKKSFMQELKQLSRVSHPNIVCLYGACRDHPVCLVMEYAEGGSLYNVLHGSGPQPQY 209
Query: 519 DLASLILYAYQLSTALAYLES---KRFVHRDIAARN-VLVSSNDCVKLGDFG 566
A + + Q + + YL K +HRD+ N +L+ +K+ DFG
Sbjct: 210 TAAHAMNWLLQCALGVEYLHGMKPKALIHRDLKPPNLLLIQCGTKLKICDFG 365
>26560
Length = 398
Score = 44.3 bits (103), Expect = 3e-04, Method: Composition-based stats.
Identities = 34/113 (30%), Positives = 59/113 (52%), Gaps = 1/113 (0%)
Frame = -1
Query: 525 LYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKL 584
YA ++ L ++ S+ V+RD+ N+L+ N V++ D GL+ + AS G
Sbjct: 344 FYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGLACDFSKKRPH-ASVGTH 168
Query: 585 PIKWMAPESI-NFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIE 636
+MAPE + + + S++D + FG CM L+ G PF+ ++N RI+
Sbjct: 167 --GYMAPEVLMKGQSYDSSADWFSFG-CMLYKLLKGHSPFR--QHNQGQARID 24
>04138
Length = 800
Score = 43.5 bits (101), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 24/85 (28%), Positives = 42/85 (49%), Gaps = 3/85 (3%)
Frame = +1
Query: 534 LAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSR-YMEDSTYYKASKGKLPIKWMAPE 592
L Y+ + +HRD+ A N+L++ +KL DFGL+R + + ++ W P
Sbjct: 52 LYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRPP 231
Query: 593 SINF--RRFTSASDVWMFGVCMWEI 615
+ R +++A D W G M E+
Sbjct: 232 ELLLGDRNYSTAIDQWGAGCIMAEM 306
>01392
Length = 1806
Score = 43.1 bits (100), Expect = 5e-04, Method: Compositional matrix adjust.
Identities = 35/123 (28%), Positives = 58/123 (47%), Gaps = 12/123 (9%)
Frame = -1
Query: 521 ASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDC---VKLGDFGLSRYME-DSTY 576
ASL++ ++ AL +L SK HRD+ N+L D VK+ DF L+ + D
Sbjct: 1785 ASLVVR--HIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGISCDGDG 1612
Query: 577 YKASKGKLPI---KWMAPESINF-----RRFTSASDVWMFGVCMWEILMHGVKPFQGVKN 628
K + P+ ++MAPE ++ + D+W G+ ++ I++ G PF G
Sbjct: 1611 TKTPELLTPVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILY-IMLCGYPPFYGQCG 1435
Query: 629 NDV 631
D
Sbjct: 1434 EDC 1426
>12786
Length = 460
Score = 41.2 bits (95), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 39/143 (27%), Positives = 69/143 (48%), Gaps = 23/143 (16%)
Frame = -3
Query: 517 SLDLASLILYAYQLSTALAYLESKRFVHRDIAARN-VLVSSNDCVKLGDFGLSRYMED-- 573
LD + Y ++ A+ L ++ +H D+ N +LV+ N +KL DFG++ ++
Sbjct: 422 GLDRMMIKFYWREMLRAVKALHNEGVIHSDLKPANFMLVAGN--LKLIDFGIANTLQQDK 249
Query: 574 STYYKASKGKLPIKWMAPESINFRRFTSA--------------------SDVWMFGVCMW 613
++ K S+ P +M+PE+I SA SDVW G C+
Sbjct: 248 TSVLKDSRVGTP-SYMSPEAIMAACDDSADDSMEEDGHRTKPKYKVGVRSDVWSLG-CIL 75
Query: 614 EILMHGVKPFQGVKNNDVIGRIE 636
+++G PFQ +KNN +G+++
Sbjct: 74 YNMVYGRTPFQHIKNN--MGKLQ 12
>03508
Length = 1463
Score = 39.7 bits (91), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 26/101 (25%), Positives = 48/101 (47%), Gaps = 2/101 (1%)
Frame = +1
Query: 525 LYAYQLSTALAYLESKRFVHRDIAARNVLVS-SNDCVKLGDFGLSRYMEDSTYYKASKGK 583
Y Y+L AL + S +HRD+ NV++ N ++L D+GL+ + Y
Sbjct: 883 FYLYELMKALDFCHSMGIMHRDVKPHNVMIDHENKKLRLIDWGLAEFYHPGMEYNVRVAS 1062
Query: 584 LPIKWMAPE-SINFRRFTSASDVWMFGVCMWEILMHGVKPF 623
K PE ++++ + + D+W G CM+ ++ +P
Sbjct: 1063RYFK--GPELLLDYQMYDYSLDMWSLG-CMFASMIFRKEPL 1176
>37602
Length = 804
Score = 39.7 bits (91), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 22/71 (30%), Positives = 32/71 (45%)
Frame = -1
Query: 495 VWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLV 554
+WI ME C G ++ V L + + L YL + +HRDI N+L+
Sbjct: 294 LWIAMEYCGGGSMQDIYHVTG-PLTEPQIAFVCRETLKGLHYLHRRGKMHRDIKGANILL 118
Query: 555 SSNDCVKLGDF 565
+ VKL DF
Sbjct: 117 TEEGDVKLADF 85
>11185
Length = 473
Score = 38.9 bits (89), Expect = 0.010, Method: Compositional matrix adjust.
Identities = 36/162 (22%), Positives = 60/162 (37%), Gaps = 21/162 (12%)
Frame = +1
Query: 526 YAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRY----MEDSTYYKASK 581
+ L T L Y+ S + D+ VL+ ++ +K DFGLS+ +E+ + A
Sbjct: 16 FGIHLVTGLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEA 195
Query: 582 G-------------KLPIK----WMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQ 624
G ++P +MAPE + SD+W G +E+
Sbjct: 196 GDQWNIQSAEEMMKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMF-------- 351
Query: 625 GVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRR 666
+G RL P+ P +L+ D +RR
Sbjct: 352 ------------SGSRLSAKPS--PEFLNLLESLLQKDSTRR 435
>38046
Length = 446
Score = 38.1 bits (87), Expect = 0.016, Method: Composition-based stats.
Identities = 14/32 (43%), Positives = 24/32 (75%)
Frame = -1
Query: 530 LSTALAYLESKRFVHRDIAARNVLVSSNDCVK 561
++ A+AY+E + F+HR++ RN+LV N+ VK
Sbjct: 98 IADAMAYMEKENFIHRNLGDRNILVGPNNRVK 3
>18481
Length = 437
Score = 38.1 bits (87), Expect = 0.018, Method: Composition-based stats.
Identities = 26/82 (31%), Positives = 44/82 (53%), Gaps = 4/82 (4%)
Frame = -1
Query: 497 IIMELCTLG-ELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVS 555
++MEL LG L + K L ++++ + QL + L ++ K F+HRD+ N L+
Sbjct: 266 LVMEL--LGPSLEELFVICKRRFTLKTILMVSDQLLSRLEFIHQKCFIHRDLKPDNFLMG 93
Query: 556 -SNDCVKLG--DFGLSRYMEDS 574
C +L DFGLS+ +D+
Sbjct: 92 LGRHCHRLYIIDFGLSKRYKDT 27
>07933
Length = 728
Score = 37.4 bits (85), Expect = 0.030, Method: Compositional matrix adjust.
Identities = 14/36 (38%), Positives = 23/36 (63%)
Frame = +3
Query: 644 PPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLRTL 679
P CP LY++M +CW+ +PS RP F +L+ + +
Sbjct: 3 PNYCPNLLYNIMMQCWSAEPSARPTFHKLEQDIVAM 110
>00486
Length = 797
Score = 36.2 bits (82), Expect = 0.065, Method: Compositional matrix adjust.
Identities = 24/81 (29%), Positives = 36/81 (44%)
Frame = -2
Query: 586 IKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPP 645
I++MAPE + A D W G M+++L G PF I +I G +L +PP
Sbjct: 766 IEYMAPEILTRTGHGKAVDWWSLGALMYDMLT-GSPPFTAENRKKTIDKILKG-KLNLPP 593
Query: 646 NCPPTLYSLMTKCWAYDPSRR 666
L+ K +P+ R
Sbjct: 592 YLTNEARGLIKKLLRKNPAER 530
>16708
Length = 1397
Score = 35.0 bits (79), Expect = 0.13, Method: Compositional matrix adjust.
Identities = 17/49 (34%), Positives = 27/49 (55%)
Frame = -1
Query: 521 ASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSR 569
A + A Q AL ++ VH D+ A NVLV ++ KL D+G+++
Sbjct: 1094 AMVCCIAGQXVCALEHIHELGVVHMDVKADNVLVDAHGNCKLTDYGIAQ 948
>26009
Length = 886
Score = 35.0 bits (79), Expect = 0.14, Method: Compositional matrix adjust.
Identities = 15/30 (50%), Positives = 21/30 (70%)
Frame = +3
Query: 529 QLSTALAYLESKRFVHRDIAARNVLVSSND 558
QL +AL ++ SK+ VHRDI NVL+ + D
Sbjct: 735 QLVSALDFMHSKQLVHRDIKPENVLILTPD 824
>02638
Length = 1490
Score = 34.7 bits (78), Expect = 0.16, Method: Compositional matrix adjust.
Identities = 28/92 (30%), Positives = 42/92 (45%), Gaps = 5/92 (5%)
Frame = +1
Query: 586 IKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKP---FQGVKNN-DVIGRIENG-ER 640
I +MAPE + + A DVW G M E M +P + N+ +I +I + +
Sbjct: 28 IAFMAPEVLRGESYGRACDVWSVGCVMIE--MCTCRPPWNSHDISNHLALIFKIASSVDP 201
Query: 641 LPMPPNCPPTLYSLMTKCWAYDPSRRPRFTEL 672
P+P N P + LM +C D RP +L
Sbjct: 202 PPIPENMSPPVRDLMLRCLEQDSDFRPSAKDL 297
>27405
Length = 532
Score = 34.3 bits (77), Expect = 0.24, Method: Compositional matrix adjust.
Identities = 14/44 (31%), Positives = 26/44 (59%)
Frame = -3
Query: 525 LYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLS 568
YA ++ L ++ S+ V+RD+ N+L+ N V++ D GL+
Sbjct: 242 FYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGLA 111
>15741
Length = 402
Score = 33.9 bits (76), Expect = 0.31, Method: Composition-based stats.
Identities = 15/44 (34%), Positives = 24/44 (54%)
Frame = -3
Query: 510 FLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVL 553
FL L +A ++ +A++ + + VHRD+AARNVL
Sbjct: 133 FLTSTANDLTARDFFSFALHVARGMAHVANNKIVHRDVAARNVL 2
>21210
Length = 518
Score = 32.3 bits (72), Expect = 0.89, Method: Compositional matrix adjust.
Identities = 27/95 (28%), Positives = 43/95 (45%), Gaps = 7/95 (7%)
Frame = +3
Query: 588 WMAPESINFRR----FTSASDVWMFGVCMWEILMHGVKPFQG-VKNNDVIGRIENGER-- 640
+MAPE I+ R + SDVW G+ + E L G P++ V D + ++ G
Sbjct: 18 YMAPERIDPRASSHGYDVRSDVWSLGITLME-LATGRFPYRKWVSIFDQLQQVVRGVAPC 194
Query: 641 LPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQ 675
LP + + KC D +RP++ +L A
Sbjct: 195 LPHDGAFSHDFVNFVNKCLTKDEKQRPKYNKLLAH 299
>27287
Length = 514
Score = 32.0 bits (71), Expect = 1.1, Method: Compositional matrix adjust.
Identities = 12/36 (33%), Positives = 19/36 (52%)
Frame = -2
Query: 644 PPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLRTL 679
PP ++ +M CW DP+ RP F+ L +L +
Sbjct: 504 PPYASSEMFGIMHSCWQEDPNDRPSFSRLVQELDKM 397
>25019
Length = 730
Score = 30.8 bits (68), Expect = 2.6, Method: Composition-based stats.
Identities = 22/62 (35%), Positives = 29/62 (46%)
Frame = +3
Query: 548 AARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWM 607
AA NVL+ + VKL DFGL + T + I++MAPE + A D W
Sbjct: 255 AAENVLLDKDGHVKLTDFGLCKEAITGTRVTHTFCG-TIEYMAPEILTRTGHGKAVDWWS 431
Query: 608 FG 609
G
Sbjct: 432 LG 437
>32359
Length = 928
Score = 30.4 bits (67), Expect = 3.2, Method: Compositional matrix adjust.
Identities = 35/128 (27%), Positives = 58/128 (45%), Gaps = 9/128 (7%)
Frame = -1
Query: 425 GRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIV 484
+ IG G FG V+Q + + + VAIK K + + LQ MR+ +H +IV
Sbjct: 415 AKVIGNGSFGVVYQAKLV---DTSELVAIK--KVLQDKRFKNRELQ---IMRKLEHQNIV 260
Query: 485 KLIGVI-------TENPVWIIMELC--TLGELRSFLQVRKYSLDLASLILYAYQLSTALA 535
KL E + +++E T+ + K ++ + + LY YQL +LA
Sbjct: 259 KLKFFFYSSGEKKDEVFLNLVLEYVPETVYRVARHYSKSKQTIPILYIKLYMYQLFRSLA 80
Query: 536 YLESKRFV 543
Y+ S+ V
Sbjct: 79 YIHSQACV 56
>06601
Length = 737
Score = 29.6 bits (65), Expect = 5.8, Method: Composition-based stats.
Identities = 19/51 (37%), Positives = 24/51 (47%)
Frame = +1
Query: 212 LDSVKAKTLRKLIQQTFRQFANLNREESILKFFEILSPVYRFDKECFKCAL 262
L S K KT L+ T+ LNR K F++ V+RF K C C L
Sbjct: 139 LRSAKTKTCESLVVSTYFY---LNRNA---KHFQLGKSVFRFHKMCLICVL 273
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000380360 | hsapiens_gene_ensembl | Protein kinase
C theta type (EC 2.7.11.13) (nPKC-theta).
[Source:Uniprot/SWISSPROT;Acc:Q04759]
(478 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
18484 192 3e-56
30755 192 2e-49
18663 145 5e-35
03240 138 5e-33
00486 128 5e-30
27405 102 3e-22
17722 101 5e-22
26156 80 4e-21
12721 96 2e-20
15910 96 3e-20
26560 95 5e-20
31885 91 1e-18
14420 86 4e-17
18921 84 9e-17
00300 83 3e-16
06405 82 3e-16
09606 79 5e-15
21433 65 7e-15
01060 77 2e-14
01707 74 1e-13
01392 73 3e-13
13212 72 4e-13
25019 71 1e-12
14126 71 1e-12
21079 65 5e-11
38560 64 2e-10
13592 63 3e-10
21808 62 5e-10
13066 61 9e-10
01756 59 4e-09
32957 59 5e-09
07940 58 1e-08
04852 58 1e-08
19094 57 2e-08
01718 57 2e-08
17932 42 4e-08
29581 55 5e-08
17591 48 8e-08
04591 55 9e-08
20152 54 1e-07
02638 52 6e-07
00392 52 8e-07
12786 50 2e-06
01966 50 2e-06
11185 50 2e-06
09007 49 4e-06
29590 49 5e-06
14116 48 9e-06
27546 47 1e-05
08294 42 2e-05
26711 46 4e-05
28638 44 2e-04
04138 44 2e-04
19761 44 2e-04
37602 43 3e-04
12672 42 6e-04
17300 41 9e-04
27274 41 9e-04
18401 41 9e-04
13305 40 0.002
17516 40 0.003
07291 39 0.004
17637 38 0.008
36002 38 0.009
20640 37 0.017
33586 36 0.029
30339 35 0.096
17975 34 0.12
25445 33 0.35
18996 33 0.37
26009 32 0.40
23319 32 0.45
19301 31 0.86
26052 30 1.9
03294 30 3.1
32359 29 4.2
13477 28 7.3
22005 28 8.5
>18484
Length = 635
Score = 192 bits (487), Expect(2) = 3e-56, Method: Compositional matrix adjust.
Identities = 94/159 (59%), Positives = 109/159 (68%)
Frame = +1
Query: 237 DLMYHIQSCHKFDLSRATFYAAEIILGLQFLHSKGIVYRXXXXXXXXXXXXGHIKIADFG 296
DLMY IQ KF A FYAAEI +GL FLH +GI+YR GHIKIADFG
Sbjct: 1 DLMYRIQQEGKFKEPVAAFYAAEIAVGLFFLHDQGIIYRDLKLDNVMLDSEGHIKIADFG 180
Query: 297 MCKENMLGDAKTNTFCGTPDYIAPEILLGQKYNHSVDWWSFGVLLYEMLIGQSPFHGQDE 356
MCKE M GDA T TFCGTPDYIAPEI+L Q Y+ SVDWW++GVLL+EML GQ PF G+DE
Sbjct: 181 MCKEGMTGDATTRTFCGTPDYIAPEIVLYQPYSKSVDWWAYGVLLFEMLAGQPPFDGEDE 360
Query: 357 EELFHSIRMDNPFYPRWLEKEAKDLLVKLFVREPEKRLG 395
+ELF SI N YP+ + +EA L L ++ P KRLG
Sbjct: 361 DELFSSITDHNVSYPKAMSREAVSLCKGLLMKNPTKRLG 477
Score = 45.4 bits (106), Expect(2) = 3e-56, Method: Compositional matrix adjust.
Identities = 18/42 (42%), Positives = 26/42 (61%)
Frame = +2
Query: 399 DIRQHPLFREINWEELERKEIDPPFRPKVKSPFDCSNFDKEF 440
DIR H FR I W++++ E+ PP++PK+ NFDK F
Sbjct: 500 DIRDHAFFRRIVWDKIKSMEVQPPYKPKITDRRKAENFDKSF 625
>30755
Length = 1137
Score = 192 bits (489), Expect = 2e-49, Method: Compositional matrix adjust.
Identities = 98/234 (41%), Positives = 137/234 (58%), Gaps = 6/234 (2%)
Frame = +2
Query: 241 HIQSCHKFDLSRATFYAAEIILGLQFLHSKGIVYRXXXXXXXXXXXXGHIKIADFGMCKE 300
H+ F R FY AEII L +LHS+GI+YR GHIK+ADFG+CKE
Sbjct: 2 HLSHERIFTEERTRFYGAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCKE 181
Query: 301 NMLGDAKTNTFCGTPDYIAPEILLGQKYNHSVDWWSFGVLLYEMLIGQSPFHGQDEEELF 360
++ T TFCGTP+Y+APE+L Y +VDWW GV++YEM+ G+ PF+ +D + LF
Sbjct: 182 DITYGRTTKTFCGTPEYLAPEVLDDNDYGRAVDWWGTGVVMYEMICGRLPFYNRDHDVLF 361
Query: 361 HSIRMDNPFYPRWLEKEAKDLLVKLFVREPEKRLGVRGD----IRQHPLFREINWEELER 416
I +++ +PR + EAK LL L ++P RLG D I+ HP F INW +L +
Sbjct: 362 TLILVEDVKFPRNITDEAKSLLSGLLAKDPRNRLGGGQDDVKEIQAHPFFASINWTDLVQ 541
Query: 417 KEIDPPFRPKVKSPFDCSNFDKEFLNEKPRLSFADRA--LINSMDQNMFRNFSF 468
K+I PPF+P+V S D FD+EF E L+ D L + ++ +F FS+
Sbjct: 542 KKITPPFKPQVTSDTDTRYFDEEFTGESVELTPPDPTGPLXSIAEEPLFPQFSY 703
>18663
Length = 600
Score = 145 bits (365), Expect = 5e-35, Method: Compositional matrix adjust.
Identities = 78/177 (44%), Positives = 103/177 (58%), Gaps = 14/177 (7%)
Frame = +2
Query: 309 NTFCGTPDYIAPEILLGQKYNHSVDWWSFGVLLYEMLIGQSPF---------HGQDEEEL 359
+TFCGTP+YIAPEIL G+ Y SVDWW+ GVLLYEML G+SPF E+ L
Sbjct: 2 STFCGTPNYIAPEILRGEDYGFSVDWWALGVLLYEMLAGRSPFDIAGASENPDQNTEDYL 181
Query: 360 FHSIRMDNPFYPRWLEKEAKDLLVKLFVREPEKRLGVRG-----DIRQHPLFREINWEEL 414
F I PR L +A +L + P RLG DI HP F+ I+WE L
Sbjct: 182 FQVILEKTIRIPRSLSVKAASVLKGFLNKNPADRLGCHRESAFMDIVNHPFFKVIDWEML 361
Query: 415 ERKEIDPPFRPKVKSPFDCSNFDKEFLNEKPRLSFADRALINSMDQNMFRNFSFMNP 471
ERK++ PPF+P++ S D +NF EF E +L+ D +I+S+DQ+ F F ++NP
Sbjct: 362 ERKQVSPPFKPRLDSDRDLANFPIEFTGEPVQLTPDDDHVIDSIDQSEFEGFEYVNP 532
>03240
Length = 1683
Score = 138 bits (348), Expect = 5e-33, Method: Compositional matrix adjust.
Identities = 98/334 (29%), Positives = 154/334 (46%), Gaps = 52/334 (15%)
Frame = -3
Query: 156 KMLGKGSFGKVFLAEFKKTNQFFAIKAXXXXXXXXXXXXECTMVEKRVLSLAWEHPFLTH 215
K LG G+FG+V L T +A+K E+ +L+ A ++ ++
Sbjct: 1273 KTLGVGAFGEVSLCRKNDTGMLYAMKTLRKSDVLKRNQVAHVKAERDILAEA-DNEWVVK 1097
Query: 216 MFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEIILGLQFLHSKGIVYR 275
++ +FQ L+FVM+Y+ GGDLM + D A FY AE++ ++ +H G ++R
Sbjct: 1096 LYYSFQDHNYLYFVMDYVPGGDLMGLLIRMEILDEPLARFYVAELVQAIESVHRMGFIHR 917
Query: 276 XXXXXXXXXXXXGHIKIADFGMC--------------------KENMLGDAKTNTFC--- 312
GHIK+ DFG+C +++M + + C
Sbjct: 916 DIKPDNILIDRNGHIKLTDFGLCTGFRWTHNSKYYQRDGTHARQDSMEVKCQLDEQCQCE 737
Query: 313 ---------------------GTPDYIAPEIL--LGQKYNHSVDWWSFGVLLYEMLIGQS 349
GTP+YIAPE+L LG Y DWWS GV+L+EML+G
Sbjct: 736 ILKPLERRRKREQRCLAHSLVGTPNYIAPEVLSRLG-GYTSVCDWWSVGVILFEMLVGHP 560
Query: 350 PFHGQDEEELFHSI--RMDNPFYPRW--LEKEAKDLLVKLFVREPEKRLGVR--GDIRQH 403
PF+ E + + D PR L + AKDL+++L + RLG+ G+I+ H
Sbjct: 559 PFYANTPAETQYKVINWKDMLKIPRESNLSQPAKDLILRLCC-GSDDRLGLNGAGEIKTH 383
Query: 404 PLFREINWEELERKEIDPPFRPKVKSPFDCSNFD 437
F +N+E L +++ PP+ P ++ D SNFD
Sbjct: 382 MFFAGVNFETLRKQQ--PPYVPNIRYATDTSNFD 287
>00486
Length = 797
Score = 128 bits (322), Expect = 5e-30, Method: Compositional matrix adjust.
Identities = 66/170 (38%), Positives = 96/170 (56%), Gaps = 4/170 (2%)
Frame = -2
Query: 308 TNTFCGTPDYIAPEILLGQKYNHSVDWWSFGVLLYEMLIGQSPFHGQDEEELFHSIRMDN 367
T+TFCGT +Y+APEIL + +VDWWS G L+Y+ML G PF ++ ++ I
Sbjct: 787 THTFCGTIEYMAPEILTRTGHGKAVDWWSLGALMYDMLTGSPPFTAENRKKTIDKILKGK 608
Query: 368 PFYPRWLEKEAKDLLVKLFVREPEKRLGV----RGDIRQHPLFREINWEELERKEIDPPF 423
P +L EA+ L+ KL + P +RLG G I+ H FR NW L + +PPF
Sbjct: 607 LNLPPYLTNEARGLIKKLLRKNPAERLGGGHDDSGPIKDHQFFRNTNWALLALRRAEPPF 428
Query: 424 RPKVKSPFDCSNFDKEFLNEKPRLSFADRALINSMDQNMFRNFSFMNPGM 473
RP V S D S FD +F + P S D L +S++Q +F+ F+++ P +
Sbjct: 427 RPNVTSDEDTSQFDTKFTRQTPVDSPDDTILSDSINQ-VFKGFTYIAPSV 281
>27405
Length = 532
Score = 102 bits (254), Expect = 3e-22, Method: Compositional matrix adjust.
Identities = 59/178 (33%), Positives = 90/178 (50%), Gaps = 4/178 (2%)
Frame = -3
Query: 162 SFGKVFLAEFKKTNQFFAIKAXXXXXXXXXXXXECTMVEKRVLSLAWE---HPFLTHMFC 218
FG+V+ T + +A+K + E+ +LSL PF+ M
Sbjct: 530 GFGEVYGCRKADTGKMYAMKCLDKKRIKMKGGETLALNERIMLSLVSTGEGSPFIVCMTY 351
Query: 219 TFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEIILGLQFLHSKGIVYRXXX 278
FQT E L F+++ +NGGDL YH+ F FYAAE++LGL+ +HS+ +VYR
Sbjct: 350 AFQTPEKLCFILDLMNGGDLHYHLSQHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLK 171
Query: 279 XXXXXXXXXGHIKIADFGMCKENMLGDAKTNTFCGTPDYIAPEILL-GQKYNHSVDWW 335
GH++I+D G+ + K + GT Y+APE+L+ GQ Y+ S DW+
Sbjct: 170 PANILLDENGHVRISDLGLACD--FSKKKPHASVGTHGYMAPEVLMKGQAYDSSADWF 3
>17722
Length = 680
Score = 101 bits (252), Expect = 5e-22, Method: Compositional matrix adjust.
Identities = 54/133 (40%), Positives = 79/133 (59%), Gaps = 5/133 (3%)
Frame = -3
Query: 332 VDWWSFGVLLYEMLIGQSPFHGQDEEELFHSIRMDNPFYPRWLEKEAKDLLVKLFVREPE 391
VDWW GV++YEM+ G+ PF+ +D + LF I + N +PR L +EAK LL L + P+
Sbjct: 678 VDWWGTGVVMYEMMCGRLPFYNRDHDVLFELILLQNVKFPRNLSEEAKTLLSGLLAKNPK 499
Query: 392 KRLGVR----GDIRQHPLFREINWEELERKEIDPPFRPKVKSPFDCSNFDKEFLNEKPRL 447
+RLG +I+ HP F+ INW++L K+I PP++P VKS +D +EF E L
Sbjct: 498 RRLGGSEADVTEIKTHPFFQCINWDDLAAKKITPPWKPDVKSSWDTKYIPEEFAQESLHL 319
Query: 448 SFA-DRALINSMD 459
+ D L +D
Sbjct: 318 TPGHDHPLAERLD 280
>26156
Length = 479
Score = 80.1 bits (196), Expect(2) = 4e-21, Method: Compositional matrix adjust.
Identities = 39/110 (35%), Positives = 61/110 (55%)
Frame = -1
Query: 146 KLKIEDFILHKMLGKGSFGKVFLAEFKKTNQFFAIKAXXXXXXXXXXXXECTMVEKRVLS 205
KL + DF+L +++G+GS+ KV E K+T + +A+K + EK V
Sbjct: 401 KLGLTDFLLLRVIGRGSYAKVLQVEHKRTKRIYAMKVIKKELVNDDEDIDWVQTEKHVFE 222
Query: 206 LAWEHPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATF 255
A +PFL + FQ++ LFFV+E++NGGDLM+H+Q + A F
Sbjct: 221 TATNYPFLVGLHSCFQSESRLFFVIEFVNGGDLMFHMQRQRRLPEEHARF 72
Score = 39.3 bits (90), Expect(2) = 4e-21, Method: Composition-based stats.
Identities = 16/22 (72%), Positives = 18/22 (81%)
Frame = -3
Query: 254 TFYAAEIILGLQFLHSKGIVYR 275
TFY+AEI L L FLH +GIVYR
Sbjct: 78 TFYSAEICLALNFLHKRGIVYR 13
>12721
Length = 821
Score = 96.3 bits (238), Expect = 2e-20, Method: Compositional matrix adjust.
Identities = 71/276 (25%), Positives = 127/276 (46%), Gaps = 13/276 (4%)
Frame = +1
Query: 131 LPEPE-LNKE--RPSLQIKLK-------IEDFILHKMLGKGSFGKVFLAEFKKTNQFFAI 180
+PEP+ L+ E R +LQ+ + ++DF+ +G+GS G V +A + Q A+
Sbjct: 10 MPEPQRLSHEQFRAALQMVVTPGDPRTFLDDFM---KIGEGSTGIVCIATSRDGRQM-AV 177
Query: 181 KAXXXXXXXXXXXXECTMVEKRVLSLAWEHPFLTHMFCTFQTKENLFFVMEYLNGGDLMY 240
K + + V+ + HP + M+ ++ + L+ VME++ GG L
Sbjct: 178 KKMDLRKQQRREL----LFNEVVVMRDYHHPNIVEMYNSYLVNDELWVVMEFMEGGALT- 342
Query: 241 HIQSCHKFDLSRATFYAAEIILGLQFLHSKGIVYRXXXXXXXXXXXXGHIKIADFGMCKE 300
I + ++ D + + L FLH+ G+++R G +K+ DFG C +
Sbjct: 343 DIVTNNRMDEVQIATVCRACLKALAFLHANGVIHRDIKSDSILLSHDGKVKLXDFGFCAQ 522
Query: 301 NMLGDAKTNTFCGTPDYIAPEILLGQKYNHSVDWWSFGVLLYEMLIGQSPFHGQDEEELF 360
K + GTP ++APE++ Y VD WS G+++ EM+ + PF + +
Sbjct: 523 VTQDLQKRKSLVGTPYWMAPEVISRLPYGPEVDIWSLGIMVMEMIDAEPPFFNEPPLQAM 702
Query: 361 HSIRMDNPFYPRWLEKEAKDL---LVKLFVREPEKR 393
IR P R K + L + ++ VR+P +R
Sbjct: 703 RRIRDMPPPKLRNTHKISPRLQGFIDRMLVRDPHQR 810
>15910
Length = 1361
Score = 95.9 bits (237), Expect = 3e-20, Method: Compositional matrix adjust.
Identities = 55/161 (34%), Positives = 90/161 (55%), Gaps = 8/161 (4%)
Frame = +2
Query: 249 DLSRATFYAAEIILGLQFLHSKGIVYRXXX---XXXXXXXXXGHIKIADFGMCKENMLGD 305
D +RA ++I+ G+Q++H+ G+V+R +K+ADFG+ + + +
Sbjct: 467 DAARAI---SDILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLADFGLSR-IIEPE 634
Query: 306 AKTNTFCGTPDYIAPEILLGQKYNHSVDWWSFGVLLYEMLIGQSPFHGQDEEELFHSI-- 363
+ +T CGTP Y APE+L G KY SVD WS GV+ Y +L G PF ++E E++ I
Sbjct: 635 VQMSTVCGTPGYCAPEVLKGDKYTPSVDMWSVGVIAYILLCGYEPFFAENEFEMYRKIIK 814
Query: 364 ---RMDNPFYPRWLEKEAKDLLVKLFVREPEKRLGVRGDIR 401
+ D ++ + + AKD++ KL V +P+KRL +R
Sbjct: 815 GEYKFDEEYWSE-ISENAKDVVRKLLVIDPKKRLTATEALR 934
>26560
Length = 398
Score = 95.1 bits (235), Expect = 5e-20, Method: Composition-based stats.
Identities = 46/121 (38%), Positives = 70/121 (57%), Gaps = 1/121 (0%)
Frame = -1
Query: 237 DLMYHIQSCHKFDLSRATFYAAEIILGLQFLHSKGIVYRXXXXXXXXXXXXGHIKIADFG 296
DL YH+ F FYAAE++LGL+ +HS+ +VYR GH++I+D G
Sbjct: 398 DLHYHLSQHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLG 219
Query: 297 MCKENMLGDAKTNTFCGTPDYIAPEILL-GQKYNHSVDWWSFGVLLYEMLIGQSPFHGQD 355
+ + + + GT Y+APE+L+ GQ Y+ S DW+SFG +LY++L G SPF +
Sbjct: 218 LACD--FSKKRPHASVGTHGYMAPEVLMKGQSYDSSADWFSFGCMLYKLLKGHSPFRQHN 45
Query: 356 E 356
+
Sbjct: 44 Q 42
>31885
Length = 529
Score = 90.5 bits (223), Expect = 1e-18, Method: Compositional matrix adjust.
Identities = 51/148 (34%), Positives = 78/148 (52%), Gaps = 5/148 (3%)
Frame = -2
Query: 209 EHPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEIILGLQFLH 268
+HPFL +++ FQ +E+LF V++ GGDL YH+Q F FY ++ L L +L
Sbjct: 498 DHPFLVNLWYAFQDEEDLFMVVDLFLGGDLRYHMQQEVSFREDCVKFYLCQLALVLDYLR 319
Query: 269 SKGIVYRXXXXXXXXXXXXGHIKIADFGMCKENMLGDAKTNTFCGTPDYIAPEIL---LG 325
S+ IV+R GH + DF + + + D + GT Y+APE+ +
Sbjct: 318 SQKIVHRDIKPDNILLDEQGHCHVTDFNIATQ-LEDDELATSTSGTRPYMAPEVYGVAIN 142
Query: 326 QK--YNHSVDWWSFGVLLYEMLIGQSPF 351
++ Y VDWWS GV L+E+L + PF
Sbjct: 141 ERRGYGFPVDWWSLGVSLFELLKKRRPF 58
>14420
Length = 528
Score = 85.9 bits (211), Expect = 4e-17, Method: Compositional matrix adjust.
Identities = 43/148 (29%), Positives = 78/148 (52%), Gaps = 1/148 (0%)
Frame = +2
Query: 209 EHPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHI-QSCHKFDLSRATFYAAEIILGLQFL 267
++P + + ++ E L+ VME+L GG L + ++C D + E + L+FL
Sbjct: 74 QNPNIVNYLDSYLVGEELWVVMEFLAGGSLTDVVTETC--MDEGQIAAVCRECLQALEFL 247
Query: 268 HSKGIVYRXXXXXXXXXXXXGHIKIADFGMCKENMLGDAKTNTFCGTPDYIAPEILLGQK 327
H +++R G +K+ DFG C + +K +T GTP ++APE++ ++
Sbjct: 248 HENQVIHRDIKSDNILLGMDGSVKLTDFGFCAQLSPEQSKRSTMVGTPYWMAPEVVTRKQ 427
Query: 328 YNHSVDWWSFGVLLYEMLIGQSPFHGQD 355
Y +VD WS GV+ EM+ G+ P+ ++
Sbjct: 428 YGPTVDIWSLGVMCIEMIEGEPPYLNEN 511
>18921
Length = 697
Score = 84.3 bits (207), Expect = 9e-17, Method: Compositional matrix adjust.
Identities = 55/198 (27%), Positives = 95/198 (47%), Gaps = 4/198 (2%)
Frame = +2
Query: 158 LGKGSFGKVFLAEFKKTNQFFAIKAXXXXXXXXXXXXECTMVEKRVLSLAWEHPFLTHMF 217
LG+GS+G VF + K+T Q AIK E +++++ + ++ +
Sbjct: 53 LGEGSYGSVFKSLHKETGQVLAIKQVPVDTDLQEIIKEISIMQQ------CDSKYIVKYY 214
Query: 218 CTFQTKENLFFVMEYLNGG---DLM-YHIQSCHKFDLSRATFYAAEIILGLQFLHSKGIV 273
++ +L+ VMEY G D+M ++ + +++ +Y + GL +LHS+ +
Sbjct: 215 GSYFKNTDLWIVMEYCGAGSVSDIMRLRNKTLVEREIATILYYTLK---GLXYLHSRRKI 385
Query: 274 YRXXXXXXXXXXXXGHIKIADFGMCKENMLGDAKTNTFCGTPDYIAPEILLGQKYNHSVD 333
+R GH K+ADFG+ + AK NT GTP ++APE++ Y+ D
Sbjct: 386 HRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTPYWMAPEVIQEIGYDCVAD 565
Query: 334 WWSFGVLLYEMLIGQSPF 351
WS G+ EM G+ P
Sbjct: 566 IWSLGITALEMAEGKPPV 619
>00300
Length = 2318
Score = 82.8 bits (203), Expect = 3e-16, Method: Compositional matrix adjust.
Identities = 63/246 (25%), Positives = 101/246 (41%), Gaps = 10/246 (4%)
Frame = -1
Query: 158 LGKGSFGKVFLAEFKKTNQFFAIKAXXXXXXXXXXXXECTMVEKRVLSLAWEHPFLTHMF 217
+G+G FGKV+ A T + A+K E M ++ + +H L +
Sbjct: 1634 IGEGQFGKVYTAVNMSTGELMALKEMKFQPNDLQQLRE--MCDEIKIFEGIQHENLVKYY 1461
Query: 218 CTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATF--YAAEIILGLQFLHSKGIVYR 275
K+ + MEY + G I+ K L Y EI+L + LH IV+R
Sbjct: 1460 GVEVHKDEMLMFMEYCDTGT----IEEAAKMGLPEYLIRRYTREIVLAVNHLHENSIVHR 1293
Query: 276 XXXXXXXXXXXXGHIKIADFGMC---KENMLGDAKTNTFCGTPDYIAPEILLGQK---YN 329
GH+K+ DFG K + + + GT Y+APE+ Y
Sbjct: 1292 DIKGANIFLTSNGHVKLGDFGCSVKLKSHTTMPGEFHNLVGTTAYMAPEVFTQNDQGGYG 1113
Query: 330 HSVDWWSFGVLLYEMLIGQSPFHGQDEE-ELFHSIRMDN-PFYPRWLEKEAKDLLVKLFV 387
+ D WS G ++ EM G+ P+H D ++ + + + + P P L E K L +
Sbjct: 1112 RAADIWSLGCVVIEMATGKRPWHDLDNNYQIMYKVGIGHKPAVPDSLSVEGKHFLDLIMC 933
Query: 388 REPEKR 393
+P +R
Sbjct: 932 HDPAQR 915
>06405
Length = 1965
Score = 82.4 bits (202), Expect = 3e-16, Method: Compositional matrix adjust.
Identities = 54/228 (23%), Positives = 102/228 (44%), Gaps = 10/228 (4%)
Frame = +1
Query: 151 DFILHKMLGKGSFGKVFLAEFKKTNQFFAIKAXXXXXXXXXXXXECTMVEKRVLSLAWEH 210
+ + LG G +G V+ A +K+ N+ A+K E + K + +H
Sbjct: 262 EIAMKHRLGGGQYGDVYEAMWKRYNKIVAVKTLKEDTMALNDFLEEAAIMKEM-----KH 426
Query: 211 PFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRAT--FYAAEIILGLQFLH 268
P L + + + V E++ G+L+ +++S + + + A +I G+ +L
Sbjct: 427 PNLVQLLGVCTREPPFYIVTEFMPHGNLLDYLRSSTREENGPTALMYMATQIASGMAYLE 606
Query: 269 SKGIVYRXXXXXXXXXXXXGHIKIADFGMCKENMLGDAKTNTFCGTP---DYIAPEILLG 325
+K ++R +K+ADFG+ + ++ D G + APE L
Sbjct: 607 TKNFIHRDLAARNCLVADSNMVKVADFGLAR--LMKDDTYTAHIGAKFPIKWTAPEGLAF 780
Query: 326 QKYNHSVDWWSFGVLLYEMLI-GQSPFHGQDEEELFH----SIRMDNP 368
+++ D W+FGVLL+E+ G SP+ G + E++H RM+ P
Sbjct: 781 NRFSTRSDIWAFGVLLWELATYGMSPYPGVELTEVYHLLERGYRMERP 924
>09606
Length = 1300
Score = 78.6 bits (192), Expect = 5e-15, Method: Compositional matrix adjust.
Identities = 59/229 (25%), Positives = 96/229 (41%), Gaps = 22/229 (9%)
Frame = -3
Query: 148 KIEDFILHKMLGKGSFGKVFLAEFKKTNQFFAIKAXXXXXXXXXXXXECTMVEKRVLSLA 207
++E+F+L++ LGKG ++ K T F AI E T + ++
Sbjct: 1121 RMENFVLYEELGKGEHSIIYKGRRKGTINFVAIHCIEKCKRP-----EVTNTVRMTHDIS 957
Query: 208 WEHPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEIILGLQFL 267
HP + ++T +L+ V+E GG L + H + + ++ GL ++
Sbjct: 956 --HPNVVQFHEWYETSNHLWLVVELCTGGSLADILAQDHHLPETSIRDFGIHLVTGLHYI 783
Query: 268 HSKGIVYRXXXXXXXXXXXXGHIKIADFGMCK---ENM---------LGDA--------- 306
HS GI++ G +K ADFG+ K EN+ GD
Sbjct: 782 HSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQWNIQSAEEM 603
Query: 307 -KTNTFCGTPDYIAPEILLGQKYNHSVDWWSFGVLLYEMLIGQSPFHGQ 354
K G+P Y+APE+ G + + D W+ G + YEM G PF G+
Sbjct: 602 MKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSGHPPFLGE 456
>21433
Length = 590
Score = 64.7 bits (156), Expect(2) = 7e-15, Method: Compositional matrix adjust.
Identities = 39/135 (28%), Positives = 62/135 (45%)
Frame = +2
Query: 252 RATFYAAEIILGLQFLHSKGIVYRXXXXXXXXXXXXGHIKIADFGMCKENMLGDAKTNTF 311
R Y ++ L++ H + +++R G +KIADFG ++ T
Sbjct: 170 RTACYIYQLSSALEYCHYRKVIHRDIKPENLLLGLKGDLKIADFGWSVHA--PSSRRTTM 343
Query: 312 CGTPDYIAPEILLGQKYNHSVDWWSFGVLLYEMLIGQSPFHGQDEEELFHSIRMDNPFYP 371
CGT DY+ PE++ G+ ++ +VD WS GVL YE L+G P + P
Sbjct: 344 CGTLDYLPPEMVEGKTHDENVDLWSLGVLCYEFLVGTPPLRPSPTRPPTPASPRWTSGSP 523
Query: 372 RWLEKEAKDLLVKLF 386
+ A+DL+ KL
Sbjct: 524 SIVTPGARDLISKLL 568
Score = 33.5 bits (75), Expect(2) = 7e-15, Method: Compositional matrix adjust.
Identities = 14/40 (35%), Positives = 22/40 (55%)
Frame = +3
Query: 210 HPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFD 249
H + MF F K ++ ++E+ G+L +Q CHKFD
Sbjct: 45 HDNILRMFGYFHDKTRVYLILEFAPKGELYKELQRCHKFD 164
>01060
Length = 1800
Score = 77.0 bits (188), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 67/246 (27%), Positives = 103/246 (41%), Gaps = 5/246 (2%)
Frame = +1
Query: 135 ELNKERPSLQIKLKIEDFILHKMLGKGSFGKVFLAEFKKTNQFFAIKAXXXXXXXXXXXX 194
+LN +R + + + D + +G+G++G V+ + T + A+K
Sbjct: 28 KLNIKRLMMDFETALSDLTDFQKIGEGTYGVVYKCRHRATGRKLAMKKIRLRGSEDGV-- 201
Query: 195 ECTMVEKRVLSLAWEHPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRAT 254
+ + + + H + + E LF V E+L+ MY + L R
Sbjct: 202 PSSAIREIAMLRELRHTNIVCLEDVIMEDERLFLVFEFLSMDLKMYIDKFPEGVVLDRRL 381
Query: 255 F--YAAEIILGLQFLHSKGIVYRXXXXXXXXXXXXGHIKIADFGMCKENMLGDAKTNTFC 312
Y +I+ G+ F H + IV+R G IKIADFGM + L
Sbjct: 382 VKSYVFQIVTGIXFCHQRRIVHRDLKPQNLLINHTGAIKIADFGMARTFALPVRAYTHEV 561
Query: 313 GTPDYIAPEILLG-QKYNHSVDWWSFGVLLYEMLIGQSPFHGQDE-EELFHSIR-MDNPF 369
T Y APEIL+G KY+ VD WS G + +MLI F G E ++LF R + P
Sbjct: 562 VTLWYRAPEILMGASKYSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPT 741
Query: 370 YPRWLE 375
W E
Sbjct: 742 EQTWPE 759
>01707
Length = 757
Score = 73.9 bits (180), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 61/224 (27%), Positives = 103/224 (45%), Gaps = 6/224 (2%)
Frame = +1
Query: 158 LGKGSFGKVFLAEFKKTNQFFAIKAXXXXXXXXXXXXECTMVEKRVLSLAWEHPFLTHMF 217
+G+GS+G VF K+T+Q AIK + M E R+L +HP L +
Sbjct: 88 IGEGSYGVVFKCRNKETSQLVAIKK-FVESEDDPLIKKIAMREIRMLK-QLKHPNLVRLI 261
Query: 218 CTFQTKENLFFVMEYLNG---GDLMYHIQSCHKFDLSRATFYAAEIILGLQFLHSKGIVY 274
F+ K+ L V +Y++ +L + + + + R + + +L + F H ++
Sbjct: 262 EVFRRKKRLHLVFDYVDHTLLNELDRYPRGLPEPMVKRIIY---QTLLAVNFCHQYNTIH 432
Query: 275 RXXXXXXXXXXXXGHIKIADFGMCK-ENMLGDAKTNTFCGTPDYIAPEILLGQ-KYNHSV 332
R G +K+ DFG + GD T+ + T Y APE+L+G +Y V
Sbjct: 433 RDVKPENILITRQGQVKLCDFGFARILTGPGDEYTD-YVATRWYRAPELLVGDTQYGPPV 609
Query: 333 DWWSFGVLLYEMLIGQSPFHGQDEEELFHSIRMD-NPFYPRWLE 375
D W+ G + E+L GQ+ + G+ + + H IR PR +E
Sbjct: 610 DVWAIGCVFAELLTGQALWPGRSDVDQLHLIRKTLGDLIPRHIE 741
>01392
Length = 1806
Score = 72.8 bits (177), Expect = 3e-13, Method: Compositional matrix adjust.
Identities = 58/184 (31%), Positives = 83/184 (45%), Gaps = 32/184 (17%)
Frame = -1
Query: 253 ATFYAAEIILGLQFLHSKGIVYRXXXXXXXXXXXXGHI---KIADFGM-----CKENMLG 304
A+ I L FLHSKGI +R + KI DF + C +
Sbjct: 1785 ASLVVRHIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGISCDGDGTK 1606
Query: 305 DAKTNTFCGTPDYIAPEIL---LGQK--YNHSVDWWSFGVLLYEMLIGQSPFHGQDEEE- 358
+ T G+ +Y+APE++ +G Y+ D WS G++LY ML G PF+GQ E+
Sbjct: 1605 TPELLTPVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILYIMLCGYPPFYGQCGEDC 1426
Query: 359 --------------LFHSIRMDNPFYP--RW--LEKEAKDLLVKLFVREPEKRLGVRGDI 400
LF+SI+ + +P W + AKDL+ L VREP KR D+
Sbjct: 1425 GWNRGEACHDCQDMLFNSIQDGHYKFPSQEWTSISSSAKDLIRHLLVREPRKRYSA-ADV 1249
Query: 401 RQHP 404
+HP
Sbjct: 1248 LKHP 1237
>13212
Length = 1067
Score = 72.0 bits (175), Expect = 4e-13, Method: Compositional matrix adjust.
Identities = 44/161 (27%), Positives = 72/161 (44%), Gaps = 8/161 (4%)
Frame = -1
Query: 255 FYAAEIILGLQFLHSKGIVYRXXXXXXXXXXXXGHIKIADFGMCKENMLGDAKTNTFCGT 314
+ E+ + L FLH +++R G +K+ADFG+ +N K +TF GT
Sbjct: 968 YVCHEMCMALDFLHRHHVIHRDIKAGNVLLTIDGEVKLADFGVSAKNTQTQQKRDTFIGT 789
Query: 315 PDYIAPEILLGQK-----YNHSVDWWSFGVLLYEMLIGQSPFHGQDEEELFHSIRMDNPF 369
P ++APE++L + Y+ D WS GV L E + P + I +P
Sbjct: 788 PYWMAPEVVLCETLKDTPYDFKADIWSLGVTLIEFAQIEPPNKEMHPMRVLIKIHKSDPP 609
Query: 370 Y---PRWLEKEAKDLLVKLFVREPEKRLGVRGDIRQHPLFR 407
P+ K KD + K V++P R ++ +HP +
Sbjct: 608 TLEKPKKWTKLFKDFIAKCLVKDPNLR-PTAAELLEHPFMK 489
>25019
Length = 730
Score = 71.2 bits (173), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 28/51 (54%), Positives = 37/51 (72%)
Frame = +3
Query: 288 GHIKIADFGMCKENMLGDAKTNTFCGTPDYIAPEILLGQKYNHSVDWWSFG 338
GH+K+ DFG+CKE + G T+TFCGT +Y+APEIL + +VDWWS G
Sbjct: 285 GHVKLTDFGLCKEAITGTRVTHTFCGTIEYMAPEILTRTGHGKAVDWWSLG 437
>14126
Length = 1265
Score = 70.9 bits (172), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 74/292 (25%), Positives = 124/292 (42%), Gaps = 40/292 (13%)
Frame = +3
Query: 157 MLGKGSFGKVFLA-EFKKTNQFFAIKAXXXXXXXXXXXXECTMVEKRVLSL-----AWEH 210
++G G++G V+ A + + +F A+K M+ R +S+ +EH
Sbjct: 210 VIGNGAYGTVYKARDLRNQGEFVAMKRIRLNNTEEG----MPMMAIREISMLKQLEQYEH 377
Query: 211 PFLTHMF----CTFQTKE-NLFFVMEYLNGGDLMYHIQSCHKFDLS--RATFYAAEIILG 263
P + + T +E L V EY+ DL ++ C L R +++ G
Sbjct: 378 PNVVRLLDVSHNTITDREIRLNLVFEYIEH-DLATYLAKCPSPGLGPDRIKDLMLQLLNG 554
Query: 264 LQFLHSKGIVYRXXXXXXXXXXXXGHIKIADFGMCKENMLGDAKTNTFCGTPDYIAPEIL 323
+ FLHS IV+R G +K+ADFG+ + A T T T Y +PE+L
Sbjct: 555 VDFLHSNRIVHRDLKPQNLLISKDGRLKLADFGLARIYSFHMALT-TVVVTLWYRSPEVL 731
Query: 324 LGQKYNHSVDWWSFGVLLYEMLIGQSPFHGQDE----EELFHSIRM-------------D 366
+ +Y SVD WS G + E+ ++ F G E +++F I +
Sbjct: 732 MQAEYGTSVDIWSCGCIFAELFTRRALFKGSSEFDQLKKIFEVIGLPPAGDWPEGVSVHR 911
Query: 367 NPFYPR----------WLEKEAKDLLVKLFVREPEKRLGVRGDIRQHPLFRE 408
N F P ++ +AKDL+ K+ V + +R+ R + HP R+
Sbjct: 912 NSFRPTPPVPLQTLVPEMDPQAKDLMEKMLVFKSGRRISSRESL-LHPYLRD 1064
>21079
Length = 878
Score = 65.5 bits (158), Expect = 5e-11, Method: Compositional matrix adjust.
Identities = 42/145 (28%), Positives = 71/145 (48%), Gaps = 4/145 (2%)
Frame = +1
Query: 210 HPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSR--ATFYAAEIILGLQFL 267
HP L ++ F+ + VME++ G+L + F L+ + +I G+ ++
Sbjct: 1 HPKLLMLWDAFEAPRTMVLVMEFVGAGELFERVIR-DDFVLTERDCVHFVRQICSGVGYM 177
Query: 268 HSKGIVYRXXX--XXXXXXXXXGHIKIADFGMCKENMLGDAKTNTFCGTPDYIAPEILLG 325
H++ I++ IKI DFG+ + GD+ F GTP++IAPE++
Sbjct: 178 HTQSILHLDLKPENVLCVSDNSNQIKIIDFGLARFYKPGDSLQVLF-GTPEFIAPEVVNY 354
Query: 326 QKYNHSVDWWSFGVLLYEMLIGQSP 350
+ N + D WS GV+ Y +L G SP
Sbjct: 355 DEINFTTDMWSIGVICYILLSGLSP 429
>38560
Length = 479
Score = 63.5 bits (153), Expect = 2e-10, Method: Composition-based stats.
Identities = 37/121 (30%), Positives = 55/121 (45%), Gaps = 5/121 (4%)
Frame = -3
Query: 305 DAKTNTFCGTPDYIAPEILLGQKY-NHSVDWWSFGVLLYEMLIGQSPFHGQDEEELFHSI 363
D T CG+P Y APE++ G +Y D WS GVLLY +L G PF + L
Sbjct: 423 DHHLTTCCGSPAYAAPELISGLEYLGSEADIWSMGVLLYALLCGYLPFDDEKXSHL*QKN 244
Query: 364 RMDNPFYPRWLEKEAKDLLVKLFVREPEKRLGVRGDIRQHPLFREIN----WEELERKEI 419
+ P WL ++ LL + +P R+ +R + H L + N W ++ +
Sbjct: 243 QKRKDEVPEWLSEDTTKLLEGMLQTDPSHRITIRRLLDHHWLNQGFNVPVEWASKYKRTL 64
Query: 420 D 420
D
Sbjct: 63 D 61
>13592
Length = 980
Score = 63.2 bits (152), Expect = 3e-10, Method: Compositional matrix adjust.
Identities = 55/246 (22%), Positives = 99/246 (40%), Gaps = 9/246 (3%)
Frame = +2
Query: 158 LGKGSFGKVFLAEFKKTNQFFAIKAXXXXXXXXXXXXECTMVEKRVLSLAWEHPFLTHMF 217
+G+G FGKV+ A T + A+K + E+ + +H L +
Sbjct: 8 IGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETRALK--NVAEELKILEGIKHKNLVRYY 181
Query: 218 CTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEIILGLQFLHSKGIVYRXX 277
+E L ME + G L ++ + + + A+++ G+ LH GIV+R
Sbjct: 182 GIEVHREELLIFMELCSEGTLESLVELTGGLPEALSRRFTAQLLSGVAELHKHGIVHRDI 361
Query: 278 XXXXXXXXXXGH-IKIADFGMC---KENMLGDAKTNTFCGTPDYIAPEILL---GQKYNH 330
+ +K+ DFG + + + + GT Y+APE+ +
Sbjct: 362 KTANIFLVDGSNSLKLGDFGSAVKIQAHTTVPGELQGYVGTQAYMAPEVFTKTNSDGHGR 541
Query: 331 SVDWWSFGVLLYEMLIGQSPFHGQDE--EELFHSIRMDNPFYPRWLEKEAKDLLVKLFVR 388
D WS G ++ EM G+ P+ D + +F + P P L +E D +
Sbjct: 542 LADIWSVGCVVVEMASGKRPWAQFDSNFQIMFKVGMGEKPQAPESLSQEGHDFIDHCLQH 721
Query: 389 EPEKRL 394
+P++RL
Sbjct: 722 DPKQRL 739
>21808
Length = 1011
Score = 62.0 bits (149), Expect = 5e-10, Method: Compositional matrix adjust.
Identities = 48/199 (24%), Positives = 81/199 (40%), Gaps = 13/199 (6%)
Frame = +1
Query: 210 HPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHK-FDLSRATFYAAEIILGLQFLH 268
HP L ++ + +F + E + G L+ +Q + L A+I G+ +L
Sbjct: 109 HPKLIQLYAVCTQDDPIFIITELMKNGSLLEFLQGKGRVLKLPALIDIGAQIACGMAYLE 288
Query: 269 SKGIVYRXXXXXXXXXXXXGHIKIADFGMCKENMLGDAKTNTFCGTP-DYIAPEILLGQK 327
S+ ++R +KIADFG+ + + + P + APE +
Sbjct: 289 SQNYIHRDLAARNILVSDNNTVKIADFGLARVIKEDEYEARVGARFPIKWTAPEAANYNR 468
Query: 328 YNHSVDWWSFGVLLYEMLI-GQSPFHGQDEEELFHSI----RM------DNPFYPRWLEK 376
+ D WSFG+LL E + G+ P+ G E+ H + RM P Y LE
Sbjct: 469 FTIKSDVWSFGILLTETVTYGRVPYPGMTNAEVLHQVEHGYRMPCPPGCPKPLYDIMLEC 648
Query: 377 EAKDLLVKLFVREPEKRLG 395
K+ + + +R P G
Sbjct: 649 WRKEEMERPHLRNPAMEAG 705
>13066
Length = 551
Score = 61.2 bits (147), Expect = 9e-10, Method: Compositional matrix adjust.
Identities = 37/134 (27%), Positives = 58/134 (43%), Gaps = 4/134 (2%)
Frame = +3
Query: 209 EHPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEIILGLQFLH 268
+HP++ + Q F M + GDL+ +IQ +A + ++ L +LH
Sbjct: 150 DHPYIIQIHSILQRXPKNFIFMRFAERGDLLTYIQEVGFVKEKQAKIWFYQMTTALNYLH 329
Query: 269 SKGIVYRXXXXXXXXXXXXGHIKIADFGM---CKENMLGDAKTNTFCGTPDYIAPEILLG 325
S + +R ++K+ADFG C + T+CG+ Y APEI+ G
Sbjct: 330 SYDVAHRDLKCENILLSSHFNVKLADFGFACACITESGEKYMSRTYCGSAAYAAPEIVYG 509
Query: 326 QKYNHSV-DWWSFG 338
Y V D WS G
Sbjct: 510 APYAPKVADAWSLG 551
>01756
Length = 1858
Score = 58.9 bits (141), Expect = 4e-09, Method: Compositional matrix adjust.
Identities = 53/213 (24%), Positives = 90/213 (42%), Gaps = 13/213 (6%)
Frame = -3
Query: 158 LGKGSFGKVFLAEFKKTNQFFAIKAXXXXXXXXXXXXECTMVEKRVLSLAWEHPF--LTH 215
+G+G+FG+VF A KKT Q A+K + E ++L L L
Sbjct: 1718 IGQGTFGEVFKARCKKTKQVVAMKKVLMDNEKEGFPI-TALREIKILQLLNHENVVDLIE 1542
Query: 216 MFCTFQTKENLFFVMEYL-------NGGDLMYHIQSCHKFDLSRATFYAAEIILGLQFLH 268
+ T T N + M YL + L+ ++ F+L +++ GL ++H
Sbjct: 1541 ICSTKATSANRYKSMFYLVFEFCEHDLAGLLSNMSVV--FNLPEIKEVMKQLMNGLYYIH 1368
Query: 269 SKGIVYRXXXXXXXXXXXXGHIKIADFGMCKENMLGDAKTNTFCG---TPDYIAPEILLG 325
I++R G +K+ADFG+ + + + N + T Y PE+LLG
Sbjct: 1367 RNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRPPELLLG 1188
Query: 326 QK-YNHSVDWWSFGVLLYEMLIGQSPFHGQDEE 357
+ Y+ ++D W G ++ EM G E+
Sbjct: 1187 DRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQ 1089
>32957
Length = 645
Score = 58.9 bits (141), Expect = 5e-09, Method: Compositional matrix adjust.
Identities = 26/58 (44%), Positives = 36/58 (62%)
Frame = +3
Query: 295 FGMCKENMLGDAKTNTFCGTPDYIAPEILLGQKYNHSVDWWSFGVLLYEMLIGQSPFH 352
F +C E G +T TFCGT +Y+APE+ ++Y VDWW G+LL+E+L Q H
Sbjct: 3 FALCVEKSGG--RTRTFCGTREYMAPEVHERKEYGKEVDWWGLGILLHELLAAQIKKH 170
>07940
Length = 1336
Score = 57.8 bits (138), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 35/109 (32%), Positives = 56/109 (51%), Gaps = 3/109 (2%)
Frame = -3
Query: 256 YAAEIILGLQFLHSKGIVYRXXXXXXXXXXXXGHIKIADFGMCKENMLGDAKTNTFCGT- 314
YA ++ G+++L SK ++R +KIADFG+ + D T G
Sbjct: 332 YAYQVARGMEYLASKQCIHRDLAARNVLVAEEYVLKIADFGLTRNLQQFDYYRKTTDGRL 153
Query: 315 -PDYIAPEILLGQKYNHSVDWWSFGVLLYEML-IGQSPFHGQDEEELFH 361
++APE L +KY D WS+GVLL+E+ +G +P+ E+LF+
Sbjct: 152 PVKWMAPEALFDRKYTSKSDVWSYGVLLWEIFTLGGNPYPSVPVEDLFN 6
>04852
Length = 1462
Score = 57.8 bits (138), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 38/120 (31%), Positives = 57/120 (47%), Gaps = 3/120 (2%)
Frame = +1
Query: 256 YAAEIILGLQFLHSKGIVYRXXXXXXXXXXXXGHIKIADFGMCKENMLGDAKTNTFCGT- 314
YA +I G++FL S+ ++R +KIADFG+ + GD G
Sbjct: 340 YAFQIARGMEFLASRKCIHRDLAARNVLVTEEHVLKIADFGLSRT---GDYYKKRSGGRL 510
Query: 315 -PDYIAPEILLGQKYNHSVDWWSFGVLLYEML-IGQSPFHGQDEEELFHSIRMDNPFYPR 372
++APE L +Y D WSFGV+L+E+ +G P+ EEL+ + D PR
Sbjct: 511 PVKWMAPEALFDMRYTTKSDVWSFGVVLWEIFSLGGMPYASIPNEELYSKLLDDAYRMPR 690
>19094
Length = 898
Score = 57.0 bits (136), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 31/86 (36%), Positives = 44/86 (51%)
Frame = +1
Query: 263 GLQFLHSKGIVYRXXXXXXXXXXXXGHIKIADFGMCKENMLGDAKTNTFCGTPDYIAPEI 322
GL +LHS+ ++R GH K+ADFG+ + AK NT GTP ++APE+
Sbjct: 94 GL*YLHSRRKIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTPYWMAPEV 273
Query: 323 LLGQKYNHSVDWWSFGVLLYEMLIGQ 348
+ Y+ D WS G+ EM G
Sbjct: 274 IQEIGYDCVADIWSLGITALEMAEGN 351
>01718
Length = 959
Score = 56.6 bits (135), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 51/221 (23%), Positives = 91/221 (41%), Gaps = 7/221 (3%)
Frame = +3
Query: 131 LPEPELNKERPSLQIKLKIEDFILHKMLGKGSFGKVFLAEFKKTNQFFAIKAXXXXXXXX 190
LP+ R ++ +++DFI K +G G F +VF + T Q A+K
Sbjct: 93 LPKSSCQALRHAVSALTRLDDFICEK-IGAGFFSEVFKVTHRITGQVMALKMNTMTSNRH 269
Query: 191 XXXXECTMVEKRVLSLAWEHPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSC-HKFD 249
E ++ + +H + + L + EY+ G+L ++ +
Sbjct: 270 NMLREVQLLNR------LQHANILRFMGVCVHEGQLHALTEYIPSGNLEQLLEKKDEELP 431
Query: 250 LSRATFYAAEIILGLQFLHSKGIVYRXXXXXXXXXXXXG----HIKIADFGMCKE--NML 303
++ + GL +LHS ++R H IADFG+ + + L
Sbjct: 432 WTQRIQLTLGLARGLDYLHSTRFIHRDLTSKNILIRREDNHGYHAVIADFGLATKIPDPL 611
Query: 304 GDAKTNTFCGTPDYIAPEILLGQKYNHSVDWWSFGVLLYEM 344
K T G+P ++APE+L G YN D +S G+++ E+
Sbjct: 612 DKEKLPTV-GSPYWMAPEVLNGHFYNERADLFSVGIIMCEI 731
>17932
Length = 597
Score = 41.6 bits (96), Expect(2) = 4e-08, Method: Compositional matrix adjust.
Identities = 22/65 (33%), Positives = 41/65 (63%)
Frame = -3
Query: 374 LEKEAKDLLVKLFVREPEKRLGVRGDIRQHPLFREINWEELERKEIDPPFRPKVKSPFDC 433
+ KEA+DL+ +L + + + RLG +++QHP F+ ++W + + PP+ P + S D
Sbjct: 460 VSKEARDLISQL-LSDGKSRLGW-PELQQHPFFKTVDWANI--RNAMPPYVPSISSLDDT 293
Query: 434 SNFDK 438
S+FD+
Sbjct: 292 SHFDE 278
Score = 33.9 bits (76), Expect(2) = 4e-08, Method: Compositional matrix adjust.
Identities = 13/22 (59%), Positives = 14/22 (63%)
Frame = -2
Query: 334 WWSFGVLLYEMLIGQSPFHGQD 355
WWS GV YEML G +PF D
Sbjct: 596 WWSLGVCAYEMLFGCTPFTDDD 531
>29581
Length = 1278
Score = 55.5 bits (132), Expect = 5e-08, Method: Compositional matrix adjust.
Identities = 40/130 (30%), Positives = 62/130 (47%), Gaps = 2/130 (1%)
Frame = -2
Query: 224 ENLFFVMEYLNGGDLMYHIQSC-HKFDLSRATFYAAEIILGLQFLHSKGIVYRXXXXXXX 282
++LF VMEY DL + + F S+ +++ GL++LH I++R
Sbjct: 1130 DSLFLVMEYCEQ-DLASLLDNMPAPFSESQVKCIVLQLLKGLRYLHEAFIIHRDLKVSNL 954
Query: 283 XXXXXGHIKIADFGMCKENMLGDAKTNTFCGTPDYIAPEILLGQK-YNHSVDWWSFGVLL 341
G +KIADFG+ + T Y APE+L G K ++ ++D WS G +L
Sbjct: 953 LMTDKGCVKIADFGLARNYGKPQKPMTPKVVTLWYRAPELLFGSKTHSTAIDMWSAGCIL 774
Query: 342 YEMLIGQSPF 351
E+L G P
Sbjct: 773 GELL-GHKPL 747
>17591
Length = 474
Score = 48.1 bits (113), Expect(2) = 8e-08, Method: Compositional matrix adjust.
Identities = 23/59 (38%), Positives = 35/59 (59%), Gaps = 3/59 (5%)
Frame = +3
Query: 388 REPEKRLGVRGD---IRQHPLFREINWEELERKEIDPPFRPKVKSPFDCSNFDKEFLNE 443
R E+RLG + D I++ F +INW++L K++ PP+ P V D +FD EF+ E
Sbjct: 141 RRKEERLGAKRDFEEIQEKAFFADINWDDLYNKKVQPPYNPNVSGQLDLRHFDPEFVRE 317
Score = 26.2 bits (56), Expect(2) = 8e-08, Method: Composition-based stats.
Identities = 9/22 (40%), Positives = 15/22 (68%)
Frame = +2
Query: 342 YEMLIGQSPFHGQDEEELFHSI 363
+EML G PF+ +D E++ +I
Sbjct: 2 FEMLYGLPPFYSRDTSEMYENI 67
>04591
Length = 1117
Score = 54.7 bits (130), Expect = 9e-08, Method: Compositional matrix adjust.
Identities = 37/137 (27%), Positives = 66/137 (48%), Gaps = 2/137 (1%)
Frame = -2
Query: 223 KENLFFVMEYLNGGDLMYHIQSCH-KFDLSRATFYAAEIILGLQFLHSKGIVYRXXXXXX 281
K + + EY + DL + + KF L+ ++++ GL ++H+K I++R
Sbjct: 981 KSTFYLIFEYCDY-DLAGLLNNLRVKFSLADKKNLMSQLLNGLFYIHTKQILHRDIKAAN 805
Query: 282 XXXXXXGHIKIADFGMCKENMLGDAKTNTFCGTPDYIAPEILLGQK-YNHSVDWWSFGVL 340
G +K+ADFG+ + + TN T Y PE+LLG++ Y +D W G +
Sbjct: 804 ILLTRDGVLKLADFGLSRPWVKSKRLTNRVV-TLWYRPPELLLGEREYGPEIDMWGVGCI 628
Query: 341 LYEMLIGQSPFHGQDEE 357
+ EM + G+ E+
Sbjct: 627 MAEMWSRKPLMQGRSEQ 577
>20152
Length = 445
Score = 54.3 bits (129), Expect = 1e-07, Method: Composition-based stats.
Identities = 33/87 (37%), Positives = 50/87 (57%), Gaps = 2/87 (2%)
Frame = +1
Query: 320 PEILLGQKYNH-SVDWWSFGVLLYEMLIGQSPFHGQDEEELFHSIRMDNPF-YPRWLEKE 377
PEILLG Y+ +VD WS GV+LY +++G++PF ++ E I MD + P + +
Sbjct: 1 PEILLGDSYDAPAVDVWSLGVILYMLVVGEAPFQEANDSETLTMI-MDCRYQIPPHISHK 177
Query: 378 AKDLLVKLFVREPEKRLGVRGDIRQHP 404
+DL+ K+ REP R + I HP
Sbjct: 178 CQDLIEKMLQREPVDRASLP-HILAHP 255
>02638
Length = 1490
Score = 51.6 bits (122), Expect = 6e-07, Method: Compositional matrix adjust.
Identities = 28/99 (28%), Positives = 49/99 (49%), Gaps = 5/99 (5%)
Frame = +1
Query: 313 GTPDYIAPEILLGQKYNHSVDWWSFGVLLYEMLIGQSPFHGQDEEELFHSI-----RMDN 367
GT ++APE+L G+ Y + D WS G ++ EM + P++ D I +D
Sbjct: 22 GTIAFMAPEVLRGESYGRACDVWSVGCVMIEMCTCRPPWNSHDISNHLALIFKIASSVDP 201
Query: 368 PFYPRWLEKEAKDLLVKLFVREPEKRLGVRGDIRQHPLF 406
P P + +DL+++ ++ + R + D+ HPLF
Sbjct: 202 PPIPENMSPPVRDLMLRCLEQDSDFRPSAK-DLLMHPLF 315
>00392
Length = 668
Score = 51.6 bits (122), Expect = 8e-07, Method: Compositional matrix adjust.
Identities = 33/151 (21%), Positives = 73/151 (48%), Gaps = 8/151 (5%)
Frame = +3
Query: 209 EHPFLTHMFCTFQ-----TKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEIILG 263
+HP + F ++ ++ + V E + G L +++ K ++ + +++ G
Sbjct: 105 QHPNIVRFFDYWEEHNHRNRKVIILVTELMTSGTLKTYLKRFKKPNVKILKNWCRQVLKG 284
Query: 264 LQFLHSKG--IVYRXXXXXXXXXXX-XGHIKIADFGMCKENMLGDAKTNTFCGTPDYIAP 320
L FLH++ +++R G +KI D G+ + + + GTP+++AP
Sbjct: 285 LYFLHTRTPPVIHRDLKCDNIFITGPTGSVKIGDLGLA--TLKNQSFAKSVIGTPEFMAP 458
Query: 321 EILLGQKYNHSVDWWSFGVLLYEMLIGQSPF 351
E + + Y+ +VD ++FG+ + EM + P+
Sbjct: 459 E-MYEEHYDEAVDVYAFGMCMLEMASSEYPY 548
>12786
Length = 460
Score = 50.1 bits (118), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 34/122 (27%), Positives = 56/122 (45%), Gaps = 24/122 (19%)
Frame = -3
Query: 255 FYAAEIILGLQFLHSKGIVYRXXXXXXXXXXXXGHIKIADFGMCKENMLGDAKTNTF--- 311
FY E++ ++ LH++G+++ G++K+ DFG+ N L KT+
Sbjct: 398 FYWREMLRAVKALHNEGVIH-SDLKPANFMLVAGNLKLIDFGIA--NTLQQDKTSVLKDS 228
Query: 312 -CGTPDYIAPEILLGQ------------------KYNHSV--DWWSFGVLLYEMLIGQSP 350
GTP Y++PE ++ KY V D WS G +LY M+ G++P
Sbjct: 227 RVGTPSYMSPEAIMAACDDSADDSMEEDGHRTKPKYKVGVRSDVWSLGCILYNMVYGRTP 48
Query: 351 FH 352
F
Sbjct: 47 FQ 42
>01966
Length = 1735
Score = 50.1 bits (118), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 39/119 (32%), Positives = 52/119 (43%), Gaps = 2/119 (1%)
Frame = -1
Query: 224 ENLFFVMEYLNGGDLMYHIQSCHKFDLSRATF--YAAEIILGLQFLHSKGIVYRXXXXXX 281
E LF V E+L+ MY + L R Y +I+ G+ F H + IV+R
Sbjct: 1495 ERLFLVFEFLSMDLKMYIDKFPEGVVLDRRLVKSYVFQIVTGINFCHQRRIVHRDLKPQN 1316
Query: 282 XXXXXXGHIKIADFGMCKENMLGDAKTNTFCGTPDYIAPEILLGQKYNHSVDWWSFGVL 340
G IKIADFGM + L T Y APEIL+G + + W+ G L
Sbjct: 1315 LLINHTGAIKIADFGMARTFALPVRAYTHEVVTLWYRAPEILMGPQ--STPPXWTCGAL 1145
Score = 31.6 bits (70), Expect = 0.66, Method: Compositional matrix adjust.
Identities = 16/42 (38%), Positives = 22/42 (52%), Gaps = 1/42 (2%)
Frame = -3
Query: 325 GQKYNHSVDWWSFGVLLYEMLIGQSPFHGQDE-EELFHSIRM 365
KY+ VD WS G + +MLI F G E ++LF R+
Sbjct: 1184 ASKYSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRI 1059
>11185
Length = 473
Score = 50.1 bits (118), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 32/115 (27%), Positives = 49/115 (42%), Gaps = 22/115 (19%)
Frame = +1
Query: 256 YAAEIILGLQFLHSKGIVYRXXXXXXXXXXXXGHIKIADFGMCK---ENM---------L 303
+ ++ GL ++HS GI++ G +K ADFG+ K EN+
Sbjct: 16 FGIHLVTGLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEA 195
Query: 304 GD----------AKTNTFCGTPDYIAPEILLGQKYNHSVDWWSFGVLLYEMLIGQ 348
GD K G+P Y+APE+ G + + D W+ G + YEM G
Sbjct: 196 GDQWNIQSAEEMMKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSGS 360
>09007
Length = 1440
Score = 49.3 bits (116), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 39/159 (24%), Positives = 72/159 (45%), Gaps = 13/159 (8%)
Frame = -1
Query: 248 FDLSRATFYAAEIILGLQFLHSKGIVYRXXXXXXXXXXXXGHIKIADFGMCKENMLGDAK 307
F + R ++ ++ G+ +L SK +V+R +KI+D G+ LG K
Sbjct: 573 FSVPRLCDFSQQVCDGMSYLESKRLVHRDLAARNILLFSKSKVKISDVGV--SGALGAGK 400
Query: 308 -------TNTFCGTPDYIAPEILLGQKYNHSVDWWSFGVLLYEMLI-GQSPFHGQDEEEL 359
T + APE ++ + D W+FGVLL+E G P+ G + +++
Sbjct: 399 EYYQSQQTIHLQNAVAWCAPESFRNLCFSSASDVWAFGVLLWEFFTHGFQPWAGLNGQQI 220
Query: 360 FHSIRMDNPFYPRWLE-----KEAKDLLVKLFVREPEKR 393
++ D P R + KE +++K + +EP++R
Sbjct: 219 MEAV--DAPQSQRLEQPDLCPKEYYAVMLKCWEQEPQRR 109
>29590
Length = 320
Score = 48.5 bits (114), Expect = 5e-06, Method: Composition-based stats.
Identities = 22/41 (53%), Positives = 26/41 (63%)
Frame = +3
Query: 313 GTPDYIAPEILLGQKYNHSVDWWSFGVLLYEMLIGQSPFHG 353
GTPDY+APE+L + + D WS GVL Y ML SPF G
Sbjct: 60 GTPDYVAPEVLDYEPLSIQTDMWSLGVLSYVMLTACSPFVG 182
>14116
Length = 1017
Score = 47.8 bits (112), Expect = 9e-06, Method: Compositional matrix adjust.
Identities = 32/123 (26%), Positives = 58/123 (47%), Gaps = 4/123 (3%)
Frame = -1
Query: 227 FFVMEYLNGGDLMYHIQS-CHKFDLSRATFYAAEIILGLQFLHSKGIVYRXXXXXXXXXX 285
V+ ++ GDL+ +I+ H+ + Y +I G+ +L V+R
Sbjct: 396 LVVLPFMKHGDLLTYIRDDQHQPTIKDLIMYGVDIARGMDYLAGLKFVHRDLAARNCMLD 217
Query: 286 XXGHIKIADFGMCKENMLGD--AKTNTFCGTP-DYIAPEILLGQKYNHSVDWWSFGVLLY 342
H+K+ADFG+ ++ + + N P ++A E L Y+ D WS+GV+L+
Sbjct: 216 EDFHVKVADFGLARDIYEKEYYSSENKKAKLPVKWMALESLEKGNYDSKTDVWSYGVVLW 37
Query: 343 EML 345
E+L
Sbjct: 36 ELL 28
>27546
Length = 426
Score = 47.4 bits (111), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 24/91 (26%), Positives = 41/91 (45%)
Frame = -1
Query: 209 EHPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEIILGLQFLH 268
+HP + + Q +F M Y GD++ HI+ D ++ + ++ LQ+LH
Sbjct: 306 DHPNIIQIHSILQRGPKIFIFMRYAEKGDMLSHIKKTGPIDEAQTKVWFFQMAKALQYLH 127
Query: 269 SKGIVYRXXXXXXXXXXXXGHIKIADFGMCK 299
S I +R ++KIADFG +
Sbjct: 126 SHDIAHRDLKCENILLSKRLNVKIADFGFAR 34
>08294
Length = 1849
Score = 41.6 bits (96), Expect(2) = 2e-05, Method: Compositional matrix adjust.
Identities = 42/207 (20%), Positives = 81/207 (39%), Gaps = 24/207 (11%)
Frame = +2
Query: 211 PFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHK------------FDLSRATFYAA 258
P + H + E F + EY + GDL + + LS+
Sbjct: 887 PNIVHFMGVCREAEPHFLITEYCDWGDLKQFLLATRNDNGRGRGTRVPALALSQKLGMGQ 1066
Query: 259 EIILGLQFLHSKGIVYRXXXXXXXXXXXXGHIKIADFGMCKENMLGDAKTNTFCGTPD-- 316
++ G++ L ++G+V+ +K+A + + GD + +
Sbjct: 1067 QVAAGMEALSNQGLVHGDLAARNVLLTSRMQLKVA-----RPALSGDVYASEYYPLHQRL 1231
Query: 317 ----YIAPEILLGQKYNHSVDWWSFGVLLYEML-IGQSPFHGQDEEELFHSIR-----MD 366
++ PE +L D W+FGV L+E+L + P+ +EE+ S++ +D
Sbjct: 1232 VPLRWLPPEGVLEDSATTCGDVWAFGVFLWEVLQLADLPYRLMSDEEVLRSLQHSQAALD 1411
Query: 367 NPFYPRWLEKEAKDLLVKLFVREPEKR 393
+P P L LL + ++P +R
Sbjct: 1412 SPDAPPAL----LSLLQRCTAQQPSQR 1480
Score = 24.3 bits (51), Expect(2) = 2e-05, Method: Compositional matrix adjust.
Identities = 9/17 (52%), Positives = 12/17 (70%)
Frame = +1
Query: 157 MLGKGSFGKVFLAEFKK 173
++GKG +G VFLA K
Sbjct: 721 IMGKGCYGDVFLARAKS 771
>26711
Length = 405
Score = 45.8 bits (107), Expect = 4e-05, Method: Composition-based stats.
Identities = 28/97 (28%), Positives = 47/97 (48%), Gaps = 2/97 (2%)
Frame = -2
Query: 264 LQFLHSKGIVYRXXXXXXXXXX--XXGHIKIADFGMCKENMLGDAKTNTFCGTPDYIAPE 321
LQ +H++G+V+ +++ DFG+ ++ + +T GTP + +PE
Sbjct: 377 LQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARK-LYPPQETFLNHGTPGFTSPE 201
Query: 322 ILLGQKYNHSVDWWSFGVLLYEMLIGQSPFHGQDEEE 358
L + + + D W GVL Y +L GQSPF E
Sbjct: 200 ALDVKPISTASDVWGVGVLAYILLSGQSPFQADSATE 90
>28638
Length = 1458
Score = 43.5 bits (101), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 24/62 (38%), Positives = 34/62 (54%)
Frame = -1
Query: 290 IKIADFGMCKENMLGDAKTNTFCGTPDYIAPEILLGQKYNHSVDWWSFGVLLYEMLIGQS 349
IKI DFG LG + + + Y +PE+LLG Y+ ++D WS G +L EM G+
Sbjct: 708 IKIVDFG--SSCQLGQ-RIYQYIQSRFYRSPEVLLGVPYDLAIDMWSLGCILVEMHTGEP 538
Query: 350 PF 351
P
Sbjct: 537 PL 532
>04138
Length = 800
Score = 43.5 bits (101), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 26/99 (26%), Positives = 45/99 (45%), Gaps = 4/99 (4%)
Frame = +1
Query: 264 LQFLHSKGIVYRXXXXXXXXXXXXGHIKIADFGMCKENMLGDAKTNTFCG---TPDYIAP 320
L ++H I++R G +K+ADFG+ + + + N + T Y P
Sbjct: 52 LYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRPP 231
Query: 321 EILLGQK-YNHSVDWWSFGVLLYEMLIGQSPFHGQDEEE 358
E+LLG + Y+ ++D W G ++ EM G E+
Sbjct: 232 ELLLGDRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQN 348
>19761
Length = 473
Score = 43.5 bits (101), Expect = 2e-04, Method: Composition-based stats.
Identities = 24/78 (30%), Positives = 39/78 (50%), Gaps = 1/78 (1%)
Frame = -3
Query: 268 HSKGIVYRXXXXXXXXXXXXGHIKIADFGMCKENMLGDAKTNTF-CGTPDYIAPEILLGQ 326
H+ I++R G +++ D G+ ++ + G A T GT Y++PEIL Q
Sbjct: 366 HTPVILHRDLKPQNIYVTEKGDVRLGDLGLARK-LTGPADFATSQVGTIMYLSPEILSQQ 190
Query: 327 KYNHSVDWWSFGVLLYEM 344
YN D WS G + Y++
Sbjct: 189 PYNSKSDIWSLGCVFYDI 136
>37602
Length = 804
Score = 43.1 bits (100), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 28/106 (26%), Positives = 45/106 (42%), Gaps = 7/106 (6%)
Frame = -1
Query: 217 FCTFQTKENLFFVMEYLNGGDL--MYHIQSCHKFDLSRATFYAAEIILGLQFLHSKGIVY 274
F ++ +E L+ MEY GG + +YH+ + F E + GL +LH +G ++
Sbjct: 321 FDSYLRREKLWIAMEYCGGGSMQDIYHVTG--PLTEPQIAFVCRETLKGLHYLHRRGKMH 148
Query: 275 RXXXXXXXXXXXXGHIKIADFGMCKENMLGDAKT-----NTFCGTP 315
R G +K+ADF N + + N F G P
Sbjct: 147 RDIKGANILLTEEGDVKLADFWRVSSNHSHNVQKKVFHWNAFIGWP 10
>12672
Length = 773
Score = 42.0 bits (97), Expect = 6e-04, Method: Compositional matrix adjust.
Identities = 32/114 (28%), Positives = 48/114 (42%), Gaps = 4/114 (3%)
Frame = +3
Query: 263 GLQFLHSKGIVYRXXXXXXXXXXXXGHIKIADFGMCKENMLGDAKT----NTFCGTPDYI 318
G+Q+L+ G V+R K+ DF G+ KT + GT Y+
Sbjct: 27 GIQYLNDNGHVHRDIKTANILLDSEYTAKVGDFATVVSAPSGEGKTVQNASVVIGTAAYL 206
Query: 319 APEILLGQKYNHSVDWWSFGVLLYEMLIGQSPFHGQDEEELFHSIRMDNPFYPR 372
APE + + +D +SFGV+L E++ G EE S M+N P
Sbjct: 207 APE-AIHFDVSTKLDSYSFGVVLLEVITGLVAQDYSREERTLSSHIMENVEEPE 365
>17300
Length = 480
Score = 41.2 bits (95), Expect = 9e-04, Method: Compositional matrix adjust.
Identities = 29/109 (26%), Positives = 50/109 (45%), Gaps = 5/109 (4%)
Frame = +1
Query: 260 IILGLQFLHSKGIVYRXXXXXXXXXXXXGHIKIADFGMCKE---NMLGDAKTNTFCGTP- 315
I G+ L G V+R K+ADFG+ +E + A T P
Sbjct: 1 ISSGMGXLADMGYVHRDLAARNILVNEILVCKVADFGLSREIESDTTEGAYTTKGGKIPV 180
Query: 316 DYIAPEILLGQKYNHSVDWWSFGVLLYE-MLIGQSPFHGQDEEELFHSI 363
+ APE + +K+ + D WSFGV+++E M G+ P+ +++ ++
Sbjct: 181 RWTAPEAIAYRKFTSASDVWSFGVVMWEVMSYGERPYWNWSNQDVIKAV 327
>27274
Length = 396
Score = 41.2 bits (95), Expect = 9e-04, Method: Composition-based stats.
Identities = 16/31 (51%), Positives = 23/31 (74%)
Frame = -1
Query: 321 EILLGQKYNHSVDWWSFGVLLYEMLIGQSPF 351
E+L GQ++ +VD WS G+LL+E+L G PF
Sbjct: 375 ELLRGQQHGPTVDMWSLGILLHELLSGHVPF 283
>18401
Length = 463
Score = 41.2 bits (95), Expect = 9e-04, Method: Compositional matrix adjust.
Identities = 17/50 (34%), Positives = 28/50 (56%)
Frame = -3
Query: 309 NTFCGTPDYIAPEILLGQKYNHSVDWWSFGVLLYEMLIGQSPFHGQDEEE 358
+T T Y APE++L ++H D WS G +++E+ G + F D +E
Sbjct: 458 STIVSTRHYRAPEVILELGWSHPCDVWSVGCIMFELYTGYTLFQTHDNKE 309
>13305
Length = 549
Score = 39.7 bits (91), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 17/49 (34%), Positives = 29/49 (59%), Gaps = 1/49 (2%)
Frame = +2
Query: 317 YIAPEILLGQKYNHSVDWWSFGVLLYEML-IGQSPFHGQDEEELFHSIR 364
++A E L Y D WSFGV+L+E+ +G +P+ D ++LF ++
Sbjct: 23 WMAVESLFNNTYTTQSDVWSFGVVLWEIFTLGGTPYSSTDTQQLFAFLK 169
>17516
Length = 453
Score = 39.7 bits (91), Expect = 0.003, Method: Composition-based stats.
Identities = 17/40 (42%), Positives = 27/40 (67%), Gaps = 1/40 (2%)
Frame = -3
Query: 310 TFCGTPDYIAPEILLGQ-KYNHSVDWWSFGVLLYEMLIGQ 348
T GTP Y+APE+LL + +Y+ D +S ++L+E+ GQ
Sbjct: 442 TLAGTPVYMAPEVLLQKGQYDMKADVYSLAIILWELWYGQ 323
>07291
Length = 833
Score = 39.3 bits (90), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 24/109 (22%), Positives = 48/109 (44%), Gaps = 4/109 (3%)
Frame = +1
Query: 256 YAAEIILGLQFLHSKGIVYRXXXXXXXXXXXXGHIKIADFGMCKENMLGDAKTNTFCGTP 315
+ +I G+ +L +V+R G ++++D+G+ T
Sbjct: 64 FGRQIADGMAYLQEVKVVHRNLAARNCIVTEDGRLQLSDYGVTGSLFPQSYYTADDSPAR 243
Query: 316 D---YIAPEILLGQKYNHSVDWWSFGVLLYEMLI-GQSPFHGQDEEELF 360
D ++APE + ++ D W+FGV+L+E+L G +P+ + L
Sbjct: 244 DLVKWMAPETIDNFHFSSKSDVWAFGVVLWELLTRGITPYPDVENSSLL 390
>17637
Length = 447
Score = 38.1 bits (87), Expect = 0.008, Method: Compositional matrix adjust.
Identities = 27/91 (29%), Positives = 44/91 (48%), Gaps = 11/91 (12%)
Frame = +1
Query: 290 IKIADFGMCKE------NMLGDAKTNTFCGTPDYIAPEILLGQKYNHSVDWWSFGVLLYE 343
+K+ D + ++ N LGD + +++ E L YN D WSFGVL++E
Sbjct: 28 VKLTDSALSRDLFSGDYNCLGDGEYRPI----KWLSLEALQKSHYNEGSDVWSFGVLMWE 195
Query: 344 ML-IGQSPFHGQDEEELFHSI----RMDNPF 369
M +G+ P+ D E+ H + R+ PF
Sbjct: 196 MCTLGKLPYAEIDPYEMEHYLKDGYRLAQPF 288
>36002
Length = 253
Score = 38.1 bits (87), Expect = 0.009, Method: Composition-based stats.
Identities = 22/53 (41%), Positives = 30/53 (56%), Gaps = 4/53 (7%)
Frame = +1
Query: 356 EEELFHSIRMDNPFYP--RW--LEKEAKDLLVKLFVREPEKRLGVRGDIRQHP 404
+E LF+ I+ N F+P W + AKDL+ L VREP KR D+ +HP
Sbjct: 49 QELLFNRIQDGNYFFPSMEWSAISSSAKDLIRHLLVREPRKRYSA-ADVLKHP 204
>20640
Length = 1492
Score = 37.0 bits (84), Expect = 0.017, Method: Compositional matrix adjust.
Identities = 23/78 (29%), Positives = 40/78 (51%), Gaps = 3/78 (3%)
Frame = +1
Query: 290 IKIADFGMCKENMLGDA-KTNTFCGTPDYIAP-EILLGQKYNHSVDWWSFGVLLYEML-I 346
+KI+DFG+ + D + + P P E +L K++ D WSFGV+L+E+
Sbjct: 61 VKISDFGLARSVHSVDYYRGSEHDAIPIRWMPLEAILYNKFSTQSDVWSFGVVLWEIFAF 240
Query: 347 GQSPFHGQDEEELFHSIR 364
P++G EE+ ++
Sbjct: 241 ALQPYYGLTHEEVVRFVK 294
>33586
Length = 551
Score = 36.2 bits (82), Expect = 0.029, Method: Compositional matrix adjust.
Identities = 17/49 (34%), Positives = 26/49 (53%)
Frame = +2
Query: 212 FLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEI 260
F+ H+ FQT+ L+ ++E+L GGDL + F FY AE+
Sbjct: 404 FIVHLHYAFQTEGKLYLILEFLRGGDLFTRLSKEVMFTEEDVKFYLAEL 550
>30339
Length = 384
Score = 34.7 bits (78), Expect = 0.096, Method: Composition-based stats.
Identities = 16/27 (59%), Positives = 19/27 (70%)
Frame = -2
Query: 146 KLKIEDFILHKMLGKGSFGKVFLAEFK 172
+ + DF K+LGKGSFGKV LAE K
Sbjct: 86 RFHLHDFNFIKVLGKGSFGKVMLAERK 6
>17975
Length = 449
Score = 34.3 bits (77), Expect = 0.12, Method: Composition-based stats.
Identities = 23/99 (23%), Positives = 45/99 (45%), Gaps = 2/99 (2%)
Frame = +3
Query: 200 EKRVLSLAWEHPFLTHMFCTFQTKENLFFVMEYLNGGDLM-YHIQSCHKFDLSRATFYAA 258
E R + L +HP + ++ T+ L+ ++E +GGD+ Y ++ + A Y
Sbjct: 114 EVRCMKLV-QHPNVVRLYEVIDTQTKLYLILELGDGGDMYDYIMRHSGGLEEKLAKRYFR 290
Query: 259 EIILGLQFLHSKGIVYRXXX-XXXXXXXXXGHIKIADFG 296
+I+ + + H +V+R G +K+ DFG
Sbjct: 291 QIVEAISYCHKLHVVHRDLKPENVVFFEKPGLVKLTDFG 407
>25445
Length = 460
Score = 32.7 bits (73), Expect = 0.35, Method: Composition-based stats.
Identities = 25/84 (29%), Positives = 36/84 (42%), Gaps = 7/84 (8%)
Frame = -1
Query: 30 LSYGLI-------ACGMNVHHRCQTKVANLCGINQKLMAEALAMIESTQQARCLRDTEQI 82
L YGLI +C MN H RC+ V LCG++ + ++ R
Sbjct: 340 LLYGLIHQGLKCDSCDMNCHKRCEKHVPRLCGMDH-----------TERRGRIY------ 212
Query: 83 FREGPVEIGLPCSIKNEARPPCLP 106
R P L ++K EA+ PC+P
Sbjct: 211 LRISPHGSKLLVNVK-EAKKPCVP 143
>18996
Length = 491
Score = 32.7 bits (73), Expect = 0.37, Method: Compositional matrix adjust.
Identities = 24/82 (29%), Positives = 39/82 (47%), Gaps = 7/82 (8%)
Frame = +2
Query: 290 IKIADFGMCK-ENMLGDAKTNTFCGTP-DYIAPEILLGQKYNHSVDWWSFGVLLYEMLIG 347
+KI+DFG+ + N G + P + +PE + K++ D WS+GV L+EM
Sbjct: 50 VKISDFGLAQFANADGYYYGISQRDIPIKWYSPEAIETCKFSSYSDVWSYGVTLFEMFSR 229
Query: 348 QS-----PFHGQDEEELFHSIR 364
P H +EE + +R
Sbjct: 230 GEIPNLLPGHDLTQEEFLNRLR 295
>26009
Length = 886
Score = 32.3 bits (72), Expect = 0.40, Method: Compositional matrix adjust.
Identities = 27/99 (27%), Positives = 43/99 (43%), Gaps = 6/99 (6%)
Frame = +2
Query: 150 EDFILHKMLGKGSFGKVFLAEFKKTNQFFAIKAXXXXXXXXXXXXECTMVE--KRVLSLA 207
E + + K LG+G++GKV LA + T A+K CT + +R L+
Sbjct: 416 EHYDVCKELGRGTYGKVVLARCRHTGTQVALK---------LLPKSCTKLREFQREFQLS 568
Query: 208 W---EHPFLTHMF-CTFQTKENLFFVMEYLNGGDLMYHI 242
+ H + + FQT+ + F E+ GDL I
Sbjct: 569 YFLSPHANIIDTYNVAFQTRSSYVFAQEHAVLGDLFDAI 685
>23319
Length = 2235
Score = 32.3 bits (72), Expect = 0.45, Method: Compositional matrix adjust.
Identities = 27/120 (22%), Positives = 45/120 (37%), Gaps = 30/120 (25%)
Frame = +3
Query: 320 PEILLGQKYNHSVDWWSFGVLLYEMLIGQSP-FHGQDEEELFHSI--RMDNPFYPRW--- 373
P++ + Y+ S+D WS G + E+ P F G D+++ I + P +W
Sbjct: 3 PDVYXAKMYSTSIDMWSAGCIFAELANAGRPLFPGNDDDDQLKRIFKLLGTPTEDQWPGM 182
Query: 374 ------------------------LEKEAKDLLVKLFVREPEKRLGVRGDIRQHPLFREI 409
L + +DLL L V P R+ + QHP F ++
Sbjct: 183 TQLPNYRMFPMYHVTTTWQQVVPKLNSKGRDLLQCLLVCCPSDRMSA-DEALQHPYFADL 359
>19301
Length = 712
Score = 31.2 bits (69), Expect = 0.86, Method: Compositional matrix adjust.
Identities = 17/69 (24%), Positives = 31/69 (44%)
Frame = +2
Query: 228 FVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEIILGLQFLHSKGIVYRXXXXXXXXXXXX 287
+MEY G L ++ + + ++ +I G+ +LHS I++R
Sbjct: 500 IIMEYCPYGQLYEVLRDGKEIPPALVLDWSKQIASGMNYLHSHKIIHRDLKSPNVLVAKN 679
Query: 288 GHIKIADFG 296
+KI+DFG
Sbjct: 680 DVVKISDFG 706
>26052
Length = 562
Score = 30.0 bits (66), Expect = 1.9, Method: Compositional matrix adjust.
Identities = 13/30 (43%), Positives = 19/30 (63%)
Frame = -1
Query: 152 FILHKMLGKGSFGKVFLAEFKKTNQFFAIK 181
++ K+LG GSFGKV + K T + A+K
Sbjct: 385 YLFXKLLGVGSFGKVMALQHKDTGETLAVK 296
>03294
Length = 1684
Score = 29.6 bits (65), Expect = 3.1, Method: Compositional matrix adjust.
Identities = 21/74 (28%), Positives = 29/74 (39%), Gaps = 18/74 (24%)
Frame = -1
Query: 330 HSVDWWSFGVLLYEMLIGQSPFHGQDE-EEL-----------------FHSIRMDNPFYP 371
H VD WS G + +MLI F G E ++L FH + N +P
Sbjct: 1678 HPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKLPAFNGMFP 1499
Query: 372 RWLEKEAKDLLVKL 385
W E + + L L
Sbjct: 1498 LWKEGKLSETLTDL 1457
>32359
Length = 928
Score = 28.9 bits (63), Expect = 4.2, Method: Compositional matrix adjust.
Identities = 12/26 (46%), Positives = 18/26 (69%)
Frame = -1
Query: 156 KMLGKGSFGKVFLAEFKKTNQFFAIK 181
K++G GSFG V+ A+ T++ AIK
Sbjct: 412 KVIGNGSFGVVYQAKLVDTSELVAIK 335
>13477
Length = 568
Score = 28.1 bits (61), Expect = 7.3, Method: Compositional matrix adjust.
Identities = 12/31 (38%), Positives = 19/31 (61%)
Frame = +3
Query: 227 FFVMEYLNGGDLMYHIQSCHKFDLSRATFYA 257
F V ++L +++ H+QS HKF S T +A
Sbjct: 297 FLVTKWLCTSNILIHLQSAHKFYFSMYTLHA 389
>22005
Length = 873
Score = 28.1 bits (61), Expect = 8.5, Method: Compositional matrix adjust.
Identities = 18/60 (30%), Positives = 30/60 (50%), Gaps = 6/60 (10%)
Frame = +1
Query: 292 IADFGMCKENMLGDAKTNTFCGTPDYIAP------EILLGQKYNHSVDWWSFGVLLYEML 345
I+DFG+ + + + G+ P E +L K++ D WSFGV+L+E+L
Sbjct: 562 ISDFGLARSV----HSVDYYRGSEQDAIPIRWMPLEAILYSKFSTQSDVWSFGVVLWEIL 729
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000262887 | hsapiens_gene_ensembl | DNA-repair
protein XRCC1 (X-ray repair cross-complementing protein 1).
[Source:Uniprot/SWISSPROT;Acc:P18887]
(633 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
00813 215 4e-56
00429 120 2e-27
02279 114 1e-25
07818 64 2e-10
>00813
Length = 2775
Score = 215 bits (548), Expect = 4e-56, Method: Compositional matrix adjust.
Identities = 118/333 (35%), Positives = 177/333 (53%), Gaps = 17/333 (5%)
Frame = +1
Query: 316 LGKILQGVVVVLSGFQNPFRSELRDKALELGAKYRPDWTRDSTHLICAFANTPKYSQVLG 375
+I++ V V+SGFQNP+R ELR+KA+E+GA Y+PDW + THL+CAF NTPKYSQV G
Sbjct: 862 FSRIMEKVTFVISGFQNPYRGELREKAMEMGAVYKPDWGKGCTHLVCAFPNTPKYSQVKG 1041
Query: 376 LGGRIVRKEWVLDCHRMRRRLPSQRYLMAGPGSSSEEDEASHSGGSGDEXXXXXXXXXXX 435
G +IV K+W+ DC++ ++ LP ++Y + G + DE+S +
Sbjct: 1042 RG-KIVSKQWISDCYKQKKXLPWKKYRL---GDAESPDESSEEEEVIRKKTPPLNKSSTS 1209
Query: 436 XXXXXXXXGPSSPQKPPTPEETKAASPVLQEDIDIEGVQSEGQDNGAEDSGDTEDELRRV 495
P+ +K Q +I ++ + G + A+D T++E+RR
Sbjct: 1210 SNKASTGSSPAVSKK--------------QVNIQLDDAKYGGDTDSADD---TDEEIRRA 1338
Query: 496 AEQKE-------HRLPPGQEENGEDPYAGSTDENTDSEEHQXXXXXXXXXXXXXXQG--- 545
E+ + ++ P + DP ++TD +E G
Sbjct: 1339 TEKPKVTKEPSPAKVKPEVKVTKPDPXLDLFADSTDEDEPPQNSAVAMDTDDSADSGLPD 1518
Query: 546 -------KHFFLYGEFPGDERRKLIRYVTAFNGELEDNMSDRVQFVITAQEWDPSFEEAL 598
KHFF YGEFP ERR L RY+ A++G LED M+DRV+FV+T WD +FEEAL
Sbjct: 1519 LPDFFADKHFFFYGEFPAAERRLLTRYIAAYDGVLEDYMTDRVKFVVTLSTWDDNFEEAL 1698
Query: 599 MDNPSLAFVRPRWIYSCNEKQKLLPHQLYGVVP 631
+NP L FV+P+W+ +C+ K ++ +Q Y VVP
Sbjct: 1699 GENPRLVFVKPQWVRTCHNKSTMVAYQPYIVVP 1797
Score = 157 bits (398), Expect = 9e-39, Method: Compositional matrix adjust.
Identities = 83/167 (49%), Positives = 118/167 (70%), Gaps = 1/167 (0%)
Frame = +1
Query: 39 GEKTISVVLQLEKEEQIHSVDIGNDGSAFVEVLVGSSAGGAGEQDYEVLLVTSSFMSPSE 98
GEK +VVLQ EK QI +DIGN+GSAFVEVLVG A + + DY+V+LV+SSFMSP++
Sbjct: 4 GEKNATVVLQFEKASQITGIDIGNEGSAFVEVLVGK-ATSSTDSDYQVILVSSSFMSPAD 180
Query: 99 SRSGSNPNRVRMFGPDKLVRAAAEKRWDRVKIVCSQPYSKDSPFGLSFVRFHSPPDKDEA 158
SRSG+N VRMF DKL + ++WDRVKIVC+QP++K + +GLSF++FH+ D +++
Sbjct: 181 SRSGNNRTSVRMFTADKLSKTVTSEKWDRVKIVCTQPFNKSTTYGLSFIKFHTGADGNKS 360
Query: 159 EAPSQKVTVTKLGQFRVKE-EDESANSLRPGALFFSRINKTSPVTAS 204
+QK V KLG F +K +DE + ++ G+LF ++ K + V S
Sbjct: 361 ---AQKEGVKKLGAFTIKRDDDEDDDDIKVGSLFANKGKKETTVAPS 492
>00429
Length = 946
Score = 120 bits (300), Expect = 2e-27, Method: Compositional matrix adjust.
Identities = 65/184 (35%), Positives = 98/184 (53%), Gaps = 17/184 (9%)
Frame = +2
Query: 465 QEDIDIEGVQSEGQDNGAEDSGDTEDELRRVAEQKE-------HRLPPGQEENGEDPYAG 517
Q +I ++ + G + A+D T++E+RR E+ + ++ P + DP
Sbjct: 227 QVNIQLDDAKYGGDTDSADD---TDEEIRRATEKPKVTKEPSPAKVKPEVKVTKPDPXLD 397
Query: 518 STDENTDSEEHQXXXXXXXXXXXXXXQG----------KHFFLYGEFPGDERRKLIRYVT 567
++TD +E G KHFF YGEFP ERR L RY+
Sbjct: 398 LFADSTDEDEPPQNSAVAMDTDDSADSGLPDLPDFFADKHFFFYGEFPAAERRLLTRYIA 577
Query: 568 AFNGELEDNMSDRVQFVITAQEWDPSFEEALMDNPSLAFVRPRWIYSCNEKQKLLPHQLY 627
A++G LED M+DRV+FV+T WD +FEEAL +NP L FV+P+W+ +C+ K ++ +Q Y
Sbjct: 578 AYDGVLEDYMTDRVKFVVTLSTWDDNFEEALGENPRLVFVKPQWVRTCHNKSTMVAYQPY 757
Query: 628 GVVP 631
VVP
Sbjct: 758 IVVP 769
>02279
Length = 781
Score = 114 bits (284), Expect = 1e-25, Method: Compositional matrix adjust.
Identities = 47/86 (54%), Positives = 64/86 (74%)
Frame = +1
Query: 546 KHFFLYGEFPGDERRKLIRYVTAFNGELEDNMSDRVQFVITAQEWDPSFEEALMDNPSLA 605
KHFF YGEFP ERR L RY+ A++G LED M+DRV+FV+T WD +FEEAL +NP L
Sbjct: 370 KHFFFYGEFPAAERRLLTRYIAAYDGVLEDYMTDRVKFVVTLSTWDDNFEEALGENPRLV 549
Query: 606 FVRPRWIYSCNEKQKLLPHQLYGVVP 631
FV+P+W+ +C+ K ++ +Q Y V+P
Sbjct: 550 FVKPQWVRTCHNKSTMVAYQPYIVIP 627
>07818
Length = 979
Score = 63.5 bits (153), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 38/109 (34%), Positives = 55/109 (50%), Gaps = 2/109 (1%)
Frame = +3
Query: 43 ISVVLQLEKEEQIHSVDIGNDGSAFVEVLVGSSAGGAGEQDYEVLLVTSSFMSPSESRSG 102
I V QL++ + +D+G A VEV VG S G Y L+ T MSP +SR G
Sbjct: 9 IEAVFQLDRPCHLAYIDVGVIWCASVEVRVGKSDWAQGTC-YVTLVPTQVLMSPLDSRLG 185
Query: 103 SNPNRVRMFGPDKLVR--AAAEKRWDRVKIVCSQPYSKDSPFGLSFVRF 149
+ NR+ MF + + WDR++++ QP+ KD GLS +R
Sbjct: 186 RHSNRMCMFSKAHFTQEGTSFSTAWDRIQVIGRQPWRKDVQMGLSSLRI 332
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000363647 | hsapiens_gene_ensembl | Kinesin-like
protein KIFC1 (Kinesin-like protein 2) (Kinesin-related protein HSET).
[Source:Uniprot/SWISSPROT;Acc:Q9BW19]
(673 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
14618 214 1e-55
12048 127 1e-29
33215 127 1e-29
11818 75 2e-20
13148 74 9e-20
36593 90 2e-18
02896 89 7e-18
28434 80 2e-15
15043 63 4e-10
34899 62 1e-09
17748 57 2e-08
34477 55 1e-07
38050 53 3e-07
19589 31 1.8
00046 29 6.8
>14618
Length = 724
Score = 214 bits (545), Expect = 1e-55, Method: Compositional matrix adjust.
Identities = 116/242 (47%), Positives = 144/242 (59%)
Frame = -2
Query: 294 EMERRRLHNQLQELKGNIRVFCRVRXXXXXXXXXXXXXXXXXXXXXXXXXXXTRLSLSRS 353
E RR+LHN +QELKGNIRVFCRVR L+
Sbjct: 717 ETVRRQLHNTIQELKGNIRVFCRVRPLLGEEAATNDGVIHHINFPDSDNKVLELDRLTEM 538
Query: 354 DERRGTLSGAPAPPTRHDFSFDRVFPPGSGQDEVFEEIAMLVQSALDGYPVCIFAYGQTG 413
TL +++FSFDRVF P + Q +VFEEI+ LVQSALDGY VCIFAYGQTG
Sbjct: 537 SMNESTLYNNRRGNNKYEFSFDRVFHPDNTQQDVFEEISQLVQSALDGYNVCIFAYGQTG 358
Query: 414 SGKTFTMEGGPGGDPQLEGLIPRALRHLFSVAQELSGQGWTYSFVASYVEIYNETVRDLL 473
SGKT+TMEGG GD +G+IPRA+ +FS A+EL +GW Y F S+VEIYNE + DLL
Sbjct: 357 SGKTYTMEGGLVGDEDTKGMIPRAVSQIFSTARELQDKGWQYKFTTSFVEIYNEMIGDLL 178
Query: 474 ATGTRKGQGGECEIRRAGPGSEELTVTNARYVPVSCEKEVDALLHLARQNRAVARTAQNE 533
++ K + + EIR AG + + VTN V V+ + E+ LL A +NRAVA T NE
Sbjct: 177 SSN--KXKNVKHEIRMAGRDN-NVAVTNLTTVDVTSQHEIAKLLRQASENRAVAATKCNE 7
Query: 534 RS 535
RS
Sbjct: 6 RS 1
>12048
Length = 1162
Score = 127 bits (320), Expect = 1e-29, Method: Compositional matrix adjust.
Identities = 92/254 (36%), Positives = 135/254 (53%), Gaps = 6/254 (2%)
Frame = +2
Query: 413 GSGKTFTMEGGPGGDPQLE-GLIPRALRHLFSVAQELSGQGWTYSFVASYVEIYNETVRD 471
G GKTFT+ GG + ++ GLIPR+L +++ Q +++ SY+EIYN++ D
Sbjct: 410 GGGKTFTITGG--AERYMDRGLIPRSLSYIYE--QTEKNPELSFTVHISYLEIYNDSGYD 577
Query: 472 LLATGTRKGQGGECE----IRRAGPGSEELTVTNARYVPVSCEKEVDALLHLARQNRAVA 527
LL K + + E + + + + N + E+E LL L NR +A
Sbjct: 578 LLDP---KHEAAKLEDLPKVNLLEDSDQNIHLRNLSVHQANSEEEALNLLFLGDTNRMIA 748
Query: 528 RTAQNERSSRSHSVFQLQISGEHSSRGLQCGAPLSLVDLAGSERLDPGLALGPGERERLR 587
T N+ SSRSH +F + I+ + A LVDLAGSER+ G + L
Sbjct: 749 ETPMNQASSRSHCIFTIHITTRETGSATIRRAKYHLVDLAGSERVAKTNVNG----QLLT 916
Query: 588 ETQAINSSLSTLGLVIMALSNKE-SHVPYRNSKLTYLLQNSLGGSAKMLMFVNISPLEEN 646
E + INSSL L LVI+ALS K HVPYRNS +T +L++SLGG+ M S + N
Sbjct: 917 EARYINSSLHFLELVIIALSEKSRQHVPYRNSMMTSVLRDSLGGNCMTTMIATCSMEKRN 1096
Query: 647 VSESLNSLRFASKV 660
+ ES+++ RFA +V
Sbjct: 1097MDESISTCRFAQRV 1138
Score = 41.2 bits (95), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 20/50 (40%), Positives = 29/50 (58%), Gaps = 1/50 (2%)
Frame = +1
Query: 377 VFPPGSGQDEVFEEIAM-LVQSALDGYPVCIFAYGQTGSGKTFTMEGGPG 425
+F P + QDEVF+ +A ++ + L GY +FAYGQTG + G G
Sbjct: 298 MF*PKTNQDEVFQNVAKPVIDNVLQGYNGTVFAYGQTGRWQDLHHHWGSG 447
>33215
Length = 696
Score = 127 bits (319), Expect = 1e-29, Method: Compositional matrix adjust.
Identities = 82/205 (40%), Positives = 119/205 (58%), Gaps = 6/205 (2%)
Frame = +1
Query: 461 YVEIYNETVRDLLATGTRKGQGGECEIR-RAGPGSEELTVTNARYVPVSCEKEVDALLHL 519
Y+EIY E +RDLL+ K Q E++ R G + V + +E++ ++++
Sbjct: 1 YLEIYQEEIRDLLS----KDQSKRLELKXRPDTG---VYVKDLSSFVTKSVREIEHVMNV 159
Query: 520 ARQNRAVARTAQNERSSRSHSVFQLQIS----GEHSSRGLQCGAPLSLVDLAGSERLDPG 575
QNR+V T NE SSRSH++F + + G ++ G L++VDLAGSER
Sbjct: 160 GNQNRSVGATNMNEHSSRSHAIFIITVECSEIGADGENHIRVG-KLNMVDLAGSERQAKT 336
Query: 576 LALGPGERERLRETQAINSSLSTLGLVIMALSN-KESHVPYRNSKLTYLLQNSLGGSAKM 634
A G +RL+E IN SLS L VI AL + K +H+PYR+SKLT LLQ+SLGG++K
Sbjct: 337 GATG----DRLKEATKINLSLSALSNVISALVDAKTTHIPYRDSKLTRLLQDSLGGNSKT 504
Query: 635 LMFVNISPLEENVSESLNSLRFASK 659
M NI P N E+L +LR+A++
Sbjct: 505 TMVANIGPASYNFDETLTTLRYANR 579
>11818
Length = 657
Score = 75.5 bits (184), Expect(2) = 2e-20, Method: Composition-based stats.
Identities = 63/183 (34%), Positives = 87/183 (47%), Gaps = 5/183 (2%)
Frame = -1
Query: 414 SGKTFTMEG----GPGGDPQLEGLIPRALRHLFSVAQELSGQGWTYSFVASYVEIYNETV 469
SGKT+TM G D L G+IPR L LF+ E S +T+ SY+EIYNE +
Sbjct: 657 SGKTYTMGGCYDAALSHDDDLVGIIPRILGDLFNGIAERSD--YTFKVTVSYLEIYNEDL 484
Query: 470 RDLLATGTRKGQGGECEIRRAGPGSEELTVTNARYVPVSCEKEVDALLHLARQNRAVART 529
DLL +++ IR G E+ + + V V ++ L ++R T
Sbjct: 483 LDLLCLPSQRQ---PLSIREEMNG--EIKIKGLKEVEVGSLEDTLMCLSQGARSRTTGAT 319
Query: 530 AQNERSSRSHSVFQLQIS-GEHSSRGLQCGAPLSLVDLAGSERLDPGLALGPGERERLRE 588
A N+ SSRSH++F + I + C A LVDLAGSER A G +E +
Sbjct: 318 AMNDTSSRSHAIFTVHIEKSKKEDMNDHCIAKFHLVDLAGSERAKKTRAEGDRFKEGVNI 139
Query: 589 TQA 591
T A
Sbjct: 138 TVA 130
Score = 42.0 bits (97), Expect(2) = 2e-20, Method: Compositional matrix adjust.
Identities = 24/43 (55%), Positives = 29/43 (67%), Gaps = 3/43 (6%)
Frame = -3
Query: 596 LSTLGLVIMALS---NKESHVPYRNSKLTYLLQNSLGGSAKML 635
L LG VI AL K H+PYR+SKLT LLQ+SLGG++ L
Sbjct: 130 LLALGNVISALGEDVQKRGHIPYRDSKLTRLLQDSLGGNSHTL 2
>13148
Length = 653
Score = 73.9 bits (180), Expect(2) = 9e-20, Method: Composition-based stats.
Identities = 63/180 (35%), Positives = 89/180 (49%)
Frame = -3
Query: 416 KTFTMEGGPGGDPQLEGLIPRALRHLFSVAQELSGQGWTYSFVASYVEIYNETVRDLLAT 475
KT TMEG G + L+G+IPR ++ +F+ + + + SY EIY + +RDLL
Sbjct: 501 KTHTMEGVLGNE-SLQGIIPRIVQDIFNYIYGMD-ENLEFHIKVSYFEIYMDKIRDLL-- 334
Query: 476 GTRKGQGGECEIRRAGPGSEELTVTNARYVPVSCEKEVDALLHLARQNRAVARTAQNERS 535
K E + P + T R+V S +EV ++ + NR VA T NE S
Sbjct: 333 DVTKTNLSVHEDKNRVPYVKGCT---ERFV--SSPEEVMEVVDEGKSNRHVAVTNMNEHS 169
Query: 536 SRSHSVFQLQISGEHSSRGLQCGAPLSLVDLAGSERLDPGLALGPGERERLRETQAINSS 595
SRSHSVF + + E+ + L LVDLAGSE++ A G L E + IN S
Sbjct: 168 SRSHSVFLIHVKQENVDSEKKLHGKLYLVDLAGSEKVSKTGAEGA----VLDEAKNINRS 1
Score = 41.6 bits (96), Expect(2) = 9e-20, Method: Composition-based stats.
Identities = 22/46 (47%), Positives = 26/46 (56%), Gaps = 1/46 (2%)
Frame = -1
Query: 372 FSFDRVFPPGSGQDEVFEEIAM-LVQSALDGYPVCIFAYGQTGSGK 416
F FD+V P Q+ V+ A +V L GY IFAYGQT SGK
Sbjct: 635 FMFDKVLKPNVTQEYVYTVTAKPIVADVLSGYNGTIFAYGQTSSGK 498
>36593
Length = 466
Score = 90.1 bits (222), Expect = 2e-18, Method: Compositional matrix adjust.
Identities = 42/51 (82%), Positives = 47/51 (92%)
Frame = +1
Query: 619 KLTYLLQNSLGGSAKMLMFVNISPLEENVSESLNSLRFASKVNQCVIGTAQ 669
KLTYLLQNSLGG++K LMFVN+SP EEN SE+LNSLRFA+KVNQC IGTAQ
Sbjct: 1 KLTYLLQNSLGGNSKTLMFVNVSPKEENFSETLNSLRFATKVNQCNIGTAQ 153
>02896
Length = 2076
Score = 88.6 bits (218), Expect = 7e-18, Method: Compositional matrix adjust.
Identities = 59/161 (36%), Positives = 94/161 (58%), Gaps = 6/161 (3%)
Frame = +1
Query: 510 EKEVDALLHLARQNRAVARTAQNERSSRSHSVFQLQISGEHSSRGLQCGAP-----LSLV 564
E+E LL NR++A + N SSRSH +F + + E SR +Q A L+ V
Sbjct: 49 EEEALNLLFEGETNRSIAAHSLNRMSSRSHCIFTVYL--ESRSR-VQSSAKYTVSKLNFV 219
Query: 565 DLAGSERLDPGLALGPGERERLRETQAINSSLSTLGLVIMALSNKE-SHVPYRNSKLTYL 623
DLAGSER+ + G + + E IN SLS L V++AL++K H+P+R SKLT+
Sbjct: 220 DLAGSERIGKSKSEG----KMVTEAMYINKSLSFLEQVVIALADKNRDHIPFRQSKLTHY 387
Query: 624 LQNSLGGSAKMLMFVNISPLEENVSESLNSLRFASKVNQCV 664
L++S+GG+ ++ N+ + E++++LRFA+++ CV
Sbjct: 388 LKDSIGGNCNTVLIANVWGERAQLEETVSTLRFATRM-MCV 507
>28434
Length = 777
Score = 80.5 bits (197), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 47/98 (47%), Positives = 61/98 (62%), Gaps = 3/98 (3%)
Frame = +2
Query: 565 DLAGSERLDPGLALGPGERERLRETQAINSSLSTLGLVIMALS---NKESHVPYRNSKLT 621
DLAGSER A G +R +E IN L LG VI AL K H+PYR+SKLT
Sbjct: 62 DLAGSERAKRTRAEG----DRFKEGVNINRGLLALGNVISALGEDVQKRGHIPYRDSKLT 229
Query: 622 YLLQNSLGGSAKMLMFVNISPLEENVSESLNSLRFASK 659
LLQ+SLGG++ LM +SP + N+ E+LN+LR+A +
Sbjct: 230 RLLQDSLGGNSHTLMVACVSPADSNMEETLNTLRYADR 343
>15043
Length = 973
Score = 63.2 bits (152), Expect = 4e-10, Method: Compositional matrix adjust.
Identities = 47/139 (33%), Positives = 75/139 (53%), Gaps = 3/139 (2%)
Frame = +2
Query: 521 RQNRAVARTAQNERSSRSHSVFQLQI-SGEHSSRGLQCGAPLSLVDLAGSERLDPGLALG 579
R+ R + T +R+H+VF + + E S + A + LV+LAG E D A
Sbjct: 29 RRARRMGATDIKAHRARAHAVFTITVEQKERQSSKVGVRANIMLVELAGCEAAD---ATD 199
Query: 580 PGERERLRETQAINSSLSTLGLVIMALSNKE--SHVPYRNSKLTYLLQNSLGGSAKMLMF 637
P + L TQ + + L LG +K+ HVPYR S +T LLQ++LGG+A LM
Sbjct: 200 P---KILAGTQGVVNVLKALG------DSKQIGGHVPYRESLVTRLLQDTLGGNAMTLML 352
Query: 638 VNISPLEENVSESLNSLRF 656
V +SPL+++ + ++L++
Sbjct: 353 VTVSPLDKSYQTTQSALQY 409
>34899
Length = 564
Score = 61.6 bits (148), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 40/103 (38%), Positives = 58/103 (56%), Gaps = 2/103 (1%)
Frame = +3
Query: 373 SFDRVFPPGSGQDEVFEE-IAMLVQSALDGYPVCIFAYGQTGSGKTFTMEGGPGGDPQLE 431
S D + P + ++++E +VQ AL+GY V I A+G TGSGK+F M G+ Q
Sbjct: 3 SLDGAYGPDAKNGQIYQEKCDSMVQRALEGYNVTIMAFGATGSGKSFLMN----GNDQEI 170
Query: 432 GLIPRALRHLFSVAQELSGQGWTYSFV-ASYVEIYNETVRDLL 473
G+ P ++ LF Q L + S V AS+VEI +E + DLL
Sbjct: 171 GVAPMVIQQLF---QHLRQRSNKESMVTASFVEILDEKMTDLL 290
>17748
Length = 621
Score = 57.0 bits (136), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 31/72 (43%), Positives = 41/72 (56%), Gaps = 4/72 (5%)
Frame = -3
Query: 399 LDGYPVCIFAYGQTGSGKTFTMEGGPGGDPQLE----GLIPRALRHLFSVAQELSGQGWT 454
GY + AYGQTGSGKTF+M G +L+ G+IPR ++ LF+ QE T
Sbjct: 373 FKGYNATVLAYGQTGSGKTFSMGGCYEASLKLDEEAMGIIPRIIKDLFNGIQERPDH--T 200
Query: 455 YSFVASYVEIYN 466
+ SY+EIYN
Sbjct: 199 FKVTVSYLEIYN 164
>34477
Length = 811
Score = 55.1 bits (131), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 43/133 (32%), Positives = 71/133 (53%), Gaps = 10/133 (7%)
Frame = +1
Query: 512 EVDALLHLARQNRAVARTAQNERSSRSHSVFQLQISGEHSSRGLQCGAPLSLVDLAGSER 571
++D ++ L +NR+V T N SSRSH++F + + E S +G G+ + +
Sbjct: 46 DMDRIMTLGNKNRSVGSTNMNMHSSRSHAIFTVTV--ECSEKGAT-GSSMYV-------W 195
Query: 572 LDPGLALGPGERERLR-ETQAI-------NSSLSTLGLVIM--ALSNKESHVPYRNSKLT 621
+ G+R++ R E QA ++ L L + + K +H+PYRNSKLT
Sbjct: 196 ANCTWWTWXGQRDKPRQEPQASA*RKRPRSTCLCQLWAM*YRSLVDGKSTHIPYRNSKLT 375
Query: 622 YLLQNSLGGSAKM 634
LLQ+SLGG++K+
Sbjct: 376 RLLQDSLGGNSKL 414
Score = 52.0 bits (123), Expect = 8e-07, Method: Compositional matrix adjust.
Identities = 36/100 (36%), Positives = 53/100 (53%), Gaps = 1/100 (1%)
Frame = +3
Query: 561 LSLVDLAGSERLDPGLALGPGERERLRETQAINSSLSTLGLVIMALSNKESHV-PYRNSK 619
L LVDLAGSER A G +RL+E IN SLSTLG VI ++ H P + +
Sbjct: 201 LHLVDLAGSERQAKTGATG----QRLKEATKINLSLSTLGNVISVPGGRQEHTHPLQELQ 368
Query: 620 LTYLLQNSLGGSAKMLMFVNISPLEENVSESLNSLRFASK 659
G + +M N+ P + N E++++LR+A++
Sbjct: 369 AHSPAAGLPGRQLQTVMVANMGPADYNYDETISTLRYANR 488
>38050
Length = 809
Score = 53.1 bits (126), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 28/58 (48%), Positives = 40/58 (68%), Gaps = 4/58 (6%)
Frame = -1
Query: 584 ERLRETQAINSSLSTLGLVIMALSNKES----HVPYRNSKLTYLLQNSLGGSAKMLMF 637
+RL+E AIN SLS LG I AL++K VP+R+S LT LL+N+LGG+A++ +
Sbjct: 446 DRLKEGAAINQSLSCLGNCISALADKAGGKNVKVPFRDSALTKLLKNALGGTARLSWW 273
Score = 45.4 bits (106), Expect = 8e-05, Method: Compositional matrix adjust.
Identities = 34/110 (30%), Positives = 56/110 (50%), Gaps = 9/110 (8%)
Frame = -2
Query: 505 VPVSCEKEVDALLHLARQNRAVARTAQNERSSRSHSVFQLQI-------SGEHSSRGLQC 557
VPV ++++ + NR VA T N SSR+H++ + +GE +++
Sbjct: 679 VPVVSYEDIEKKMEAGTTNRTVAATNMNATSSRAHTIVGITFMQKFKNAAGEETTK---- 512
Query: 558 GAPLSLVDLAGSERLDPGLALGPGERERLRETQ--AINSSLSTLGLVIMA 605
A ++LVDLAGSER D A G R+ + T + ++S L L+ +A
Sbjct: 511 SALINLVDLAGSERADSTGATGTD*RKGRQSTNRSPVWGTVSPLWLIRLA 362
>19589
Length = 1142
Score = 30.8 bits (68), Expect = 1.8, Method: Compositional matrix adjust.
Identities = 15/35 (42%), Positives = 22/35 (62%), Gaps = 1/35 (2%)
Frame = +2
Query: 388 FEEIAMLVQS-ALDGYPVCIFAYGQTGSGKTFTME 421
FE+I V+S LDG C++ G G+GKT T++
Sbjct: 563 FEDIYRFVESKVLDGTGGCMYISGVPGTGKTATVK 667
>00046
Length = 1969
Score = 28.9 bits (63), Expect = 6.8, Method: Compositional matrix adjust.
Identities = 13/37 (35%), Positives = 21/37 (56%)
Frame = -1
Query: 453 WTYSFVASYVEIYNETVRDLLATGTRKGQGGECEIRR 489
+TY +++ V Y + +R +L+T K GGEC R
Sbjct: 1783 YTYVYISVCVCNYIQIIRSILSTVALKYFGGECYYPR 1673
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000248846 | hsapiens_gene_ensembl | Gamma-tubulin
complex component 6 (GCP-6). [Source:Uniprot/SWISSPROT;Acc:Q96RT7]
(1819 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
32473 215 2e-55
28481 77 8e-14
35557 75 2e-13
24313 33 1.3
14986 32 1.8
15801 32 2.3
01284 30 7.6
>32473
Length = 1077
Score = 215 bits (547), Expect = 2e-55, Method: Composition-based stats.
Identities = 102/196 (52%), Positives = 135/196 (68%), Gaps = 1/196 (0%)
Frame = +2
Query: 1622 SKYSGVFSFLLQLKLMMWALKDVCFHLKRTALLSHMAGSVQFRQLQLFKHEMQHFVKVIQ 1681
+ Y VFSF+LQLK + W L D + LKR A++ + S QFRQLQL + EM HFV+V+Q
Sbjct: 8 ASYGQVFSFMLQLKRVAWTLTDCWYRLKRDAMVKNAKDSRQFRQLQLHRQEMLHFVRVLQ 187
Query: 1682 GYIANQILHVTWCEFRARL-ATVGDLEEIQRAHAEYLHKAVFRGLLTEKAAPVMNVIHSI 1740
GY+ NQI+ VTW E + L +V L++++R HA+YL+KA+FR LL +KAAP+M+ I +I
Sbjct: 188 GYMGNQIIQVTWRELQQSLDHSVHSLDDLKRVHADYLNKALFRCLLNKKAAPIMSKIQNI 367
Query: 1741 FSLVLKFRSQLISQAWGPPGGPRGAEHPNFALMQQSYNTFKYYSHFLFKVVTKLVNRGYQ 1800
F L+LKF + L S W G HPNFA M ++ FK Y FLFKVV+KL RGYQ
Sbjct: 368 FCLILKFCAHLASATWEQDEGTGEVIHPNFAAMVSAFKAFKEYFVFLFKVVSKLAERGYQ 547
Query: 1801 PHLEDFLLRINFNNYY 1816
PHL + LLR+NFN+YY
Sbjct: 548 PHLHELLLRLNFNHYY 595
>28481
Length = 869
Score = 76.6 bits (187), Expect = 8e-14, Method: Compositional matrix adjust.
Identities = 51/183 (27%), Positives = 90/183 (49%), Gaps = 15/183 (8%)
Frame = -2
Query: 1565 ALQCSLHGD-TPHASNLSLALKYLPEVFAPNAPDVLSCLELRYKVDWPLNIVITEGCVSK 1623
ALQ +L HAS LS+ ++ + + +A + CL L + V WP+++V+ C++
Sbjct: 781 ALQEALQSHHAQHASLLSITMETMSKTRERSAVNATDCLRLHFAVPWPVDVVVNSRCLNL 602
Query: 1624 YSGVFSFLLQLKLMMWALKDVCFH-LKRTALLS-------------HMAGSVQFRQLQLF 1669
Y+ VF FLLQ+K + L + F L +T+L + ++ S + +L +
Sbjct: 601 YNQVFRFLLQIKRAKYGLDQLRFSGLDKTSLQTVSSVSDSGSRSEETVSRSERLHRLHVR 422
Query: 1670 KHEMQHFVKVIQGYIANQILHVTWCEFRARLATVGDLEEIQRAHAEYLHKAVFRGLLTEK 1729
+ + +FV + YI +ILH T EF + DLE++ H Y+ + + L K
Sbjct: 421 RFRLAYFVNSLHNYIMTRILHSTGLEFAGEVKRATDLEQVIEIHGRYV-RTIHERCLLHK 245
Query: 1730 AAP 1732
+P
Sbjct: 244 NSP 236
>35557
Length = 306
Score = 75.5 bits (184), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 34/70 (48%), Positives = 50/70 (71%)
Frame = +3
Query: 1480 LPVLMKRSITAPLAAHISLVNKAAVDYFFVELHLEAHYEALRHFLLMEDGEFAQSLSDLL 1539
L VL+++S+TAPL A ISLV++ V+YF EL ++ H +AL +L M DG+FAQ+L+D+L
Sbjct: 93 LSVLLQQSLTAPLTAQISLVDEMVVNYFLGELRIDGHLQALHSYLFMADGDFAQNLTDIL 272
Query: 1540 FEKLGAGQTP 1549
+KL P
Sbjct: 273 LDKLSTSHLP 302
>24313
Length = 937
Score = 32.7 bits (73), Expect = 1.3, Method: Compositional matrix adjust.
Identities = 15/42 (35%), Positives = 25/42 (59%)
Frame = -1
Query: 947 RPQEYDFSTVLRPAVATSPAPGPLQAAECSLGSSGLQLWEDS 988
RP +D+S+ + P+V S LQ+ +CS+ SS + W +S
Sbjct: 919 RPMTFDYSSQVLPSVDQSQLQHGLQSDDCSVSSSNSKCWPNS 794
>14986
Length = 914
Score = 32.3 bits (72), Expect = 1.8, Method: Composition-based stats.
Identities = 15/38 (39%), Positives = 18/38 (47%)
Frame = +3
Query: 294 RRCWERVGCPPGHREEPYLTEAGRDAFDKFCRLHQGEL 331
R+ W VGC R E GRD F K +H GE+
Sbjct: 123 RQSWAVVGCGNETRSGKVAEERGRDVF*KLTTMHWGEI 236
>15801
Length = 854
Score = 32.0 bits (71), Expect = 2.3, Method: Composition-based stats.
Identities = 14/40 (35%), Positives = 23/40 (57%)
Frame = -1
Query: 1474 LSELLTLPVLMKRSITAPLAAHISLVNKAAVDYFFVELHL 1513
L LLT P++ + P A++S +NKA V + F+ +L
Sbjct: 848 LKHLLTGPIVYRLQFIIPYPAYVSNINKAFVKHLFLAFYL 729
>01284
Length = 1603
Score = 30.4 bits (67), Expect = 7.6, Method: Composition-based stats.
Identities = 37/195 (18%), Positives = 81/195 (41%), Gaps = 20/195 (10%)
Frame = +2
Query: 631 EELKEIEKDCAVYVGRMERVARHSSVSKEEKELRMEIAKQELIAHAREAASRVLSALSDR 690
+++KE+E Y+ ++ R +++S+EE M +L+ + + S + L +
Sbjct: 698 KQVKELEAALTAYIHKI----RTTNISREE----MSRTTNQLMTNMDTSLSDLKKQLEKQ 853
Query: 691 QMSERMALDARKREQFQR--------------------LKEQFVKDQERRQAARQEELDD 730
+++E + +E+ +R LK + +++ + AR+++ ++
Sbjct: 854 KVAEEQQRLRKIQEEMERERKRKEDEERKRREEEEQRRLKAEMESKRKKEEEARKKQEEE 1033
Query: 731 DFSYAXXXXXXXXXXXXXXXXXXXKARQALVDHYSKLSAEAARREQKALWRIQRHRLESA 790
D KA QAL +K S E A+R+ + Q HR
Sbjct: 1034D----------------------KKAAQALQVELAKQSKEQAQRQAQL---DQEHRDREL 1138
Query: 791 RLRFLLEDEKHIQEM 805
LR +ED+ ++++
Sbjct: 1139ALRLAMEDQNAVEDV 1183
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000336740 | hsapiens_gene_ensembl | LIM domain
kinase 1 (EC 2.7.11.1) (LIMK-1). [Source:Uniprot/SWISSPROT;Acc:P53667]
(647 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
01718 213 2e-55
06405 127 1e-29
21808 109 4e-24
18921 107 1e-23
14116 104 1e-22
12721 99 7e-21
14420 92 7e-19
09007 89 6e-18
04852 87 2e-17
01060 87 2e-17
11780 87 2e-17
00300 86 4e-17
01707 82 8e-16
07291 81 1e-15
13592 81 1e-15
01756 80 3e-15
14126 75 1e-13
00715 73 5e-13
19301 72 1e-12
07940 71 1e-12
19094 69 7e-12
00392 69 7e-12
03240 68 1e-11
13212 65 8e-11
01966 65 9e-11
09606 64 1e-10
27546 64 1e-10
04591 64 1e-10
07836 63 5e-10
17300 62 5e-10
08294 62 7e-10
12672 62 9e-10
17975 61 1e-09
20640 61 1e-09
11928 61 2e-09
30755 61 2e-09
13066 60 2e-09
29581 60 2e-09
07833 60 3e-09
21079 60 4e-09
14477 60 4e-09
18484 59 8e-09
26560 58 1e-08
17253 58 1e-08
15910 57 2e-08
19761 56 6e-08
27405 54 3e-07
09680 53 3e-07
21433 53 3e-07
22005 52 6e-07
31885 52 6e-07
01392 50 4e-06
04138 47 2e-05
17806 46 4e-05
11185 46 6e-05
17637 45 1e-04
20559 44 1e-04
03508 44 2e-04
14307 44 3e-04
16708 43 5e-04
05726 42 6e-04
18996 42 8e-04
32359 41 0.002
07437 39 0.009
13305 39 0.009
37602 37 0.023
30169 37 0.025
00394 37 0.030
17516 36 0.045
31789 35 0.096
31489 34 0.17
02638 34 0.20
18663 33 0.32
17982 33 0.36
38046 33 0.39
08228 32 0.65
26052 32 0.73
04349 32 0.74
01106 32 0.87
15741 32 1.0
38751 32 1.2
37063 31 1.3
21800 31 1.3
03831 31 1.3
03731 31 1.5
05103 31 1.6
26009 31 1.8
32264 31 1.9
35055 30 2.1
38560 30 2.4
05111 30 2.9
18481 30 3.0
25550 30 4.4
26762 29 6.0
07933 29 6.6
>01718
Length = 959
Score = 213 bits (542), Expect = 2e-55, Method: Compositional matrix adjust.
Identities = 106/277 (38%), Positives = 161/277 (58%), Gaps = 4/277 (1%)
Frame = +3
Query: 343 EVLGKGCFGQAIKVTHRETGEVMVMKELIRFDEETQRTFLKEVKVMRCLEHPNVLKFIGV 402
E +G G F + KVTHR TG+VM +K + + L+EV+++ L+H N+L+F+GV
Sbjct: 165 EKIGAGFFSEVFKVTHRITGQVMALK--MNTMTSNRHNMLREVQLLNRLQHANILRFMGV 338
Query: 403 LYKDKRLNFITEYIKGGTLRGIIKSMDSQYPWSQRVSFAKDIASGMAYLHSMNIIHRDLN 462
+ +L+ +TEYI G L +++ D + PW+QR+ +A G+ YLHS IHRDL
Sbjct: 339 CVHEGQLHALTEYIPSGNLEQLLEKKDEELPWTQRIQLTLGLARGLDYLHSTRFIHRDLT 518
Query: 463 SHNCLVRENKN----VVVADFGLARLMVDEKTQPEGLRSLKKPDRKKRYTVVGNPYWMAP 518
S N L+R N V+ADFGLA + D P K++ VG+PYWMAP
Sbjct: 519 SKNILIRREDNHGYHAVIADFGLATKIPD-------------PLDKEKLPTVGSPYWMAP 659
Query: 519 EMINGRSYDEKVDVFSFGIVLCEIIGRVNADPDYLPRTMDFGLNVRGFLDRYCPPNCPPS 578
E++NG Y+E+ D+FS GI++CEI R+ ADPD +PR +FG++ + CP
Sbjct: 660 EVLNGHFYNERADLFSVGIIMCEITARIPADPDIMPRMNNFGVDYVALSEMIS--YCPLD 833
Query: 579 FFPITVRCCDLDPEKRPSFVKLEHWLETLRMHLAGHL 615
+ + +CC +DP+KRP V++ WLE + +L +
Sbjct: 834 YLQLAFKCCQVDPQKRPRGVEIIEWLEKIFKNLKNDI 944
>06405
Length = 1965
Score = 127 bits (319), Expect = 1e-29, Method: Compositional matrix adjust.
Identities = 80/269 (29%), Positives = 138/269 (51%), Gaps = 6/269 (2%)
Frame = +1
Query: 345 LGKGCFGQAIKVTHRETGEVMVMKELIRFDEETQRTFLKEVKVMRCLEHPNVLKFIGVLY 404
LG G +G + + +++ +K L + D FL+E +M+ ++HPN+++ +GV
Sbjct: 283 LGGGQYGDVYEAMWKRYNKIVAVKTL-KEDTMALNDFLEEAAIMKEMKHPNLVQLLGVCT 459
Query: 405 KDKRLNFITEYIKGGTLRGIIKSMDSQYPWSQRVSF-AKDIASGMAYLHSMNIIHRDLNS 463
++ +TE++ G L ++S + + + A IASGMAYL + N IHRDL +
Sbjct: 460 REPPFYIVTEFMPHGNLLDYLRSSTREENGPTALMYMATQIASGMAYLETKNFIHRDLAA 639
Query: 464 HNCLVRENKNVVVADFGLARLMVDEKTQPEGLRSLKKPDRKKRYTV-VGNPY---WMAPE 519
NCLV ++ V VADFGLARLM D+ YT +G + W APE
Sbjct: 640 RNCLVADSNMVKVADFGLARLMKDDT-----------------YTAHIGAKFPIKWTAPE 768
Query: 520 MINGRSYDEKVDVFSFGIVLCEIIGRVNADPDYLPRTMDFGLNVRGF-LDRYCPPNCPPS 578
+ + + D+++FG++L E+ + + T + L RG+ ++R PP P
Sbjct: 769 GLAFNRFSTRSDIWAFGVLLWELATYGMSPYPGVELTEVYHLLERGYRMER--PPGTPAD 942
Query: 579 FFPITVRCCDLDPEKRPSFVKLEHWLETL 607
+ + ++C DP+ RP+F ++ LE +
Sbjct: 943 VYILMLKCWQWDPKDRPTFKEIHFLLENM 1029
>21808
Length = 1011
Score = 109 bits (272), Expect = 4e-24, Method: Compositional matrix adjust.
Identities = 79/258 (30%), Positives = 116/258 (44%), Gaps = 8/258 (3%)
Frame = +1
Query: 379 RTFLKEVKVMRCLEHPNVLKFIGVLYKDKRLNFITEYIKGGTLRGIIKSMDSQYPWSQRV 438
+ FL E ++M+ L HP +++ V +D + ITE +K G+L ++ +
Sbjct: 67 KDFLAEAQIMKKLRHPKLIQLYAVCTQDDPIFIITELMKNGSLLEFLQGKGRVLKLPALI 246
Query: 439 SFAKDIASGMAYLHSMNIIHRDLNSHNCLVRENKNVVVADFGLARLMVDEKTQPEGLRSL 498
IA GMAYL S N IHRDL + N LV +N V +ADFGLAR+ +
Sbjct: 247 DIGAQIACGMAYLESQNYIHRDLAARNILVSDNNTVKIADFGLARV-------------I 387
Query: 499 KKPDRKKRYTVVGNPYWMAPEMINGRSYDEKVDVFSFGIVLCEII--------GRVNADP 550
K+ + + R W APE N + K DV+SFGI+L E + G NA+
Sbjct: 388 KEDEYEARVGARFPIKWTAPEAANYNRFTIKSDVWSFGILLTETVTYGRVPYPGMTNAE- 564
Query: 551 DYLPRTMDFGLNVRGFLDRYCPPNCPPSFFPITVRCCDLDPEKRPSFVKLEHWLETLRMH 610
+ ++ G + CPP CP + I + C + +RP L M
Sbjct: 565 --VLHQVEHGYRMP------CPPGCPKPLYDIMLECWRKEEMERPH-------LRNPAME 699
Query: 611 LAGHLPLGPQLEQLDRGF 628
G L G L++L R F
Sbjct: 700 AGGILYHG--LQRLQRSF 747
>18921
Length = 697
Score = 107 bits (268), Expect = 1e-23, Method: Compositional matrix adjust.
Identities = 61/198 (30%), Positives = 101/198 (51%)
Frame = +2
Query: 345 LGKGCFGQAIKVTHRETGEVMVMKELIRFDEETQRTFLKEVKVMRCLEHPNVLKFIGVLY 404
LG+G +G K H+ETG+V+ +K+ + D + Q +KE+ +M+ + ++K+ G +
Sbjct: 53 LGEGSYGSVFKSLHKETGQVLAIKQ-VPVDTDLQE-IIKEISIMQQCDSKYIVKYYGSYF 226
Query: 405 KDKRLNFITEYIKGGTLRGIIKSMDSQYPWSQRVSFAKDIASGMAYLHSMNIIHRDLNSH 464
K+ L + EY G++ I++ + + + G+ YLHS IHRD+ +
Sbjct: 227 KNTDLWIVMEYCGAGSVSDIMRLRNKTLVEREIATILYYTLKGLXYLHSRRKIHRDIKAG 406
Query: 465 NCLVRENKNVVVADFGLARLMVDEKTQPEGLRSLKKPDRKKRYTVVGNPYWMAPEMINGR 524
N L+ + +ADFG+A + D KR TV+G PYWMAPE+I
Sbjct: 407 NILLNNEGHAKLADFGVAGQLTDTMA--------------KRNTVIGTPYWMAPEVIQEI 544
Query: 525 SYDEKVDVFSFGIVLCEI 542
YD D++S GI E+
Sbjct: 545 GYDCVADIWSLGITALEM 598
>14116
Length = 1017
Score = 104 bits (259), Expect = 1e-22, Method: Compositional matrix adjust.
Identities = 68/214 (31%), Positives = 109/214 (50%), Gaps = 7/214 (3%)
Frame = -1
Query: 339 LIHGEVLGKGCFG---QAIKVTHRETGEVMVMKELIRFD---EETQRTFLKEVKVMRCLE 392
L GE +GKG FG + + G+++V + + + E ++FL+E +M+
Sbjct: 630 LTMGEEIGKGNFGCVKRGFLTLPEQKGDILVAVKTLHNNNPREIELQSFLQEALIMKDFH 451
Query: 393 HPNVLKFIGV-LYKDKRLNFITEYIKGGTLRGIIKSMDSQYPWSQRVSFAKDIASGMAYL 451
H NVL IG+ L D + ++K G L I+ Q + + DIA GM YL
Sbjct: 450 HSNVLTLIGICLNLDDMPLVVLPFMKHGDLLTYIRDDQHQPTIKDLIMYGVDIARGMDYL 271
Query: 452 HSMNIIHRDLNSHNCLVRENKNVVVADFGLARLMVDEKTQPEGLRSLKKPDRKKRYTVVG 511
+ +HRDL + NC++ E+ +V VADFGLAR + +++ + K P +
Sbjct: 270 AGLKFVHRDLAARNCMLDEDFHVKVADFGLARDIYEKEYYSSENKKAKLPVK-------- 115
Query: 512 NPYWMAPEMINGRSYDEKVDVFSFGIVLCEIIGR 545
WMA E + +YD K DV+S+G+VL E++ R
Sbjct: 114 ---WMALESLEKGNYDSKTDVWSYGVVLWELLTR 22
>12721
Length = 821
Score = 98.6 bits (244), Expect = 7e-21, Method: Compositional matrix adjust.
Identities = 61/209 (29%), Positives = 108/209 (51%)
Frame = +1
Query: 345 LGKGCFGQAIKVTHRETGEVMVMKELIRFDEETQRTFLKEVKVMRCLEHPNVLKFIGVLY 404
+G+G G T R+ G M +K++ ++ + EV VMR HPN+++
Sbjct: 112 IGEGSTGIVCIATSRD-GRQMAVKKMDLRKQQRRELLFNEVVVMRDYHHPNIVEMYNSYL 288
Query: 405 KDKRLNFITEYIKGGTLRGIIKSMDSQYPWSQRVSFAKDIASGMAYLHSMNIIHRDLNSH 464
+ L + E+++GG L I+ +++ Q + + +A+LH+ +IHRD+ S
Sbjct: 289 VNDELWVVMEFMEGGALTDIVT--NNRMDEVQIATVCRACLKALAFLHANGVIHRDIKSD 462
Query: 465 NCLVRENKNVVVADFGLARLMVDEKTQPEGLRSLKKPDRKKRYTVVGNPYWMAPEMINGR 524
+ L+ + V + DFG + TQ D +KR ++VG PYWMAPE+I+
Sbjct: 463 SILLSHDGKVKLXDFGFCA----QVTQ----------DLQKRKSLVGTPYWMAPEVISRL 600
Query: 525 SYDEKVDVFSFGIVLCEIIGRVNADPDYL 553
Y +VD++S GI++ E+I +A+P +
Sbjct: 601 PYGPEVDIWSLGIMVMEMI---DAEPPFF 678
>14420
Length = 528
Score = 92.0 bits (227), Expect = 7e-19, Method: Compositional matrix adjust.
Identities = 50/178 (28%), Positives = 90/178 (50%), Gaps = 2/178 (1%)
Frame = +2
Query: 378 QRTFLKEVKVMRCLEHPNVLKFIGVLYKDKRLNFITEYIKGGTLRGIIKS--MDSQYPWS 435
+ + E+ VMR ++PN++ ++ + L + E++ GG+L ++ MD
Sbjct: 32 KELIINEILVMRENQNPNIVNYLDSYLVGEELWVVMEFLAGGSLTDVVTETCMDE----G 199
Query: 436 QRVSFAKDIASGMAYLHSMNIIHRDLNSHNCLVRENKNVVVADFGLARLMVDEKTQPEGL 495
Q + ++ + +LH +IHRD+ S N L+ + +V + DFG +
Sbjct: 200 QIAAVCRECLQALEFLHENQVIHRDIKSDNILLGMDGSVKLTDFGFCAQL---------- 349
Query: 496 RSLKKPDRKKRYTVVGNPYWMAPEMINGRSYDEKVDVFSFGIVLCEIIGRVNADPDYL 553
P++ KR T+VG PYWMAPE++ + Y VD++S G++ E+I +P YL
Sbjct: 350 ----SPEQSKRSTMVGTPYWMAPEVVTRKQYGPTVDIWSLGVMCIEMI---EGEPPYL 502
>09007
Length = 1440
Score = 89.0 bits (219), Expect = 6e-18, Method: Compositional matrix adjust.
Identities = 75/309 (24%), Positives = 142/309 (45%), Gaps = 21/309 (6%)
Frame = -1
Query: 321 SESLRVVCRPHR---IFRPSDLIHGEVLGKGCFG---QAIKVTHRETGE-VMVMKELIRF 373
S + V RP R + + + LG+G FG QAI E+GE V V + +
Sbjct: 936 SRPVSAVVRPARGKQLISKDCVALSKSLGQGHFGTVRQAIWTA--ESGEKVQVAVKCLSK 763
Query: 374 DE--ETQRTFLKEVKVMRCLEHPNVLKFIGVLYKD-KRLNFITEYIKGGTLRGIIKSMDS 430
D+ + + FLKE +M+ L+H N+++ GV+ + + +TE +L +K + +
Sbjct: 762 DKIHKDGQEFLKETAIMQMLDHENIVRVYGVVMDNGADIMLVTELAPMRSLLECVKEVSA 583
Query: 431 QYPWS--QRVSFAKDIASGMAYLHSMNIIHRDLNSHNCLVRENKNVVVADFGLARLMVDE 488
+ +S + F++ + GM+YL S ++HRDL + N L+ V ++D G++ +
Sbjct: 582 RVDFSVPRLCDFSQQVCDGMSYLESKRLVHRDLAARNILLFSKSKVKISDVGVSGALGAG 403
Query: 489 KTQPEGLRSLKKPDRKKRYTVVGNPYWMAPEMINGRSYDEKVDVFSFGIVLCEIIGRVNA 548
K + +++ + W APE + DV++FG++L E
Sbjct: 402 KEYYQSQQTIH---------LQNAVAWCAPESFRNLCFSSASDVWAFGVLLWEFFTH--- 259
Query: 549 DPDYLPRTMDFGLNVRGFLDRYCPPN---------CPPSFFPITVRCCDLDPEKRPSFVK 599
+ P GLN + ++ P CP ++ + ++C + +P++RP+F +
Sbjct: 258 --GFQPWA---GLNGQQIMEAVDAPQSQRLEQPDLCPKEYYAVMLKCWEQEPQRRPTFSQ 94
Query: 600 LEHWLETLR 608
L L +R
Sbjct: 93 LFLTLPQIR 67
>04852
Length = 1462
Score = 87.0 bits (214), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 78/283 (27%), Positives = 122/283 (43%), Gaps = 28/283 (9%)
Frame = +1
Query: 355 KVTHRETGEVMVMKELIRFDEETQRTFLKEVKVMRCLE----HPNVLKFIGVLYKDKRLN 410
+V T V ++++++ EE + F++E++VM+ ++ H N++ F+G + L
Sbjct: 7 RVPKASTVAVKMLRDIVTAVEE--QDFVQELQVMKAVKKMGSHINIVNFLGCCTQGGPLW 180
Query: 411 FITEYIKGGTLRGIIKS-----------MDSQYP-WSQR------------VSFAKDIAS 446
I E+ K G LR ++S + Q P W + +S+A IA
Sbjct: 181 VIVEFAKNGNLRDFLESCRDGINGYGKFVSPQDPGWYTKTPGGHVIRRKNLLSYAFQIAR 360
Query: 447 GMAYLHSMNIIHRDLNSHNCLVRENKNVVVADFGLARLMVDEKTQPEGLRSLKKPDRKKR 506
GM +L S IHRDL + N LV E + +ADFGL+R K + G +K
Sbjct: 361 GMEFLASRKCIHRDLAARNVLVTEEHVLKIADFGLSRTGDYYKKRSGGRLPVK------- 519
Query: 507 YTVVGNPYWMAPEMINGRSYDEKVDVFSFGIVLCEIIGRVNADPDYLPRTMDFGLNVRGF 566
WMAPE + Y K DV+SFG+VL EI +P + +
Sbjct: 520 --------WMAPEALFDMRYTTKSDVWSFGVVLWEIFSLGGMPYASIPNEELYSKLLDDA 675
Query: 567 LDRYCPPNCPPSFFPITVRCCDLDPEKRPSFVKLEHWLETLRM 609
P + + I RC P RP F +L ++ L M
Sbjct: 676 YRMPRPELASGNLYAIMERCWLNRPSDRPEFSQLVGHIDRLLM 804
>01060
Length = 1800
Score = 87.0 bits (214), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 61/214 (28%), Positives = 107/214 (50%), Gaps = 5/214 (2%)
Frame = +1
Query: 337 SDLIHGEVLGKGCFGQAIKVTHRETGEVMVMKEL-IRFDEE-TQRTFLKEVKVMRCLEHP 394
SDL + +G+G +G K HR TG + MK++ +R E+ + ++E+ ++R L H
Sbjct: 73 SDLTDFQKIGEGTYGVVYKCRHRATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELRHT 252
Query: 395 NVLKFIGVLYKDKRLNFITEYIKGGTLRGIIKSMDSQYPWSQRV--SFAKDIASGMAYLH 452
N++ V+ +D+RL + E++ L+ I +R+ S+ I +G+ + H
Sbjct: 253 NIVCLEDVIMEDERLFLVFEFL-SMDLKMYIDKFPEGVVLDRRLVKSYVFQIVTGIXFCH 429
Query: 453 SMNIIHRDLNSHNCLVRENKNVVVADFGLARLMVDEKTQPEGLRSLKKPDRKKRYTVVGN 512
I+HRDL N L+ + +ADFG+A R+ P R + VV
Sbjct: 430 QRRIVHRDLKPQNLLINHTGAIKIADFGMA-------------RTFALPVRAYTHEVV-T 567
Query: 513 PYWMAPEMINGRS-YDEKVDVFSFGIVLCEIIGR 545
++ APE++ G S Y VDV+S G + +++ R
Sbjct: 568 LWYRAPEILMGASKYSTPVDVWSIGTIFADMLIR 669
>11780
Length = 1713
Score = 86.7 bits (213), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 53/153 (34%), Positives = 84/153 (54%), Gaps = 1/153 (0%)
Frame = +3
Query: 333 IFRPSDLIHGEVLGKGCFGQAIKVTHRETGEVMVMKELIRFDEETQRTFLKEVKVMRCLE 392
+ DL GE +GKG FG K +R G+ + +K+L D Q +FL+E VM L
Sbjct: 585 VIAXQDLEIGEAIGKGDFGDVYKGMYR--GQPVAIKQLKDKDRGEQ-SFLQEASVMTSLR 755
Query: 393 HPNVLKFIGVLYKDKRLNFITEYIKGGTLRGIIKSMD-SQYPWSQRVSFAKDIASGMAYL 451
H N+++ IGV+ + + +TE++ G L ++S S +++FA D + M YL
Sbjct: 756 HDNLVRLIGVVLGET-IFLVTEFMGKGNLVEYLRSRGRSVITKKDQINFATDTCAAMEYL 932
Query: 452 HSMNIIHRDLNSHNCLVRENKNVVVADFGLARL 484
S ++HRDL + N LV ++ V+DFGLA+
Sbjct: 933 ESKRLVHRDLAARNVLVHDDGKAKVSDFGLAKF 1031
Score = 41.2 bits (95), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 24/72 (33%), Positives = 36/72 (50%)
Frame = +1
Query: 526 YDEKVDVFSFGIVLCEIIGRVNADPDYLPRTMDFGLNVRGFLDRYCPPNCPPSFFPITVR 585
+ K D++SFGI+L EI +P T D ++V P CPP + I +
Sbjct: 1105 FTSKSDMWSFGILLWEIYSFGRVPYPRIPLT-DVVMHVERGYRMEAPEGCPPEIYSIMKQ 1281
Query: 586 CCDLDPEKRPSF 597
+LDP +RP+F
Sbjct: 1282 AWELDPNERPTF 1317
>00300
Length = 2318
Score = 86.3 bits (212), Expect = 4e-17, Method: Compositional matrix adjust.
Identities = 59/208 (28%), Positives = 102/208 (49%), Gaps = 7/208 (3%)
Frame = -1
Query: 342 GEVLGKGCFGQAIKVTHRETGEVMVMKELIRF---DEETQRTFLKEVKVMRCLEHPNVLK 398
G +G+G FG+ + TGE+M +KE+ +F D + R E+K+ ++H N++K
Sbjct: 1643 GNKIGEGQFGKVYTAVNMSTGELMALKEM-KFQPNDLQQLREMCDEIKIFEGIQHENLVK 1467
Query: 399 FIGV-LYKDKRLNFITEYIKGGTLRGIIKSMDSQYPWSQRVSFAKDIASGMAYLHSMNII 457
+ GV ++KD+ L F+ EY GT+ K +Y + + ++I + +LH +I+
Sbjct: 1466 YYGVEVHKDEMLMFM-EYCDTGTIEEAAKMGLPEYLIRR---YTREIVLAVNHLHENSIV 1299
Query: 458 HRDLNSHNCLVRENKNVVVADFGLARLMVDEKTQPEGLRSLKKPDRKKRYTVVGNPYWMA 517
HRD+ N + N +V + DFG + + T P +L VG +MA
Sbjct: 1298 HRDIKGANIFLTSNGHVKLGDFGCSVKLKSHTTMPGEFHNL-----------VGTTAYMA 1152
Query: 518 PEMINGRS---YDEKVDVFSFGIVLCEI 542
PE+ Y D++S G V+ E+
Sbjct: 1151 PEVFTQNDQGGYGRAADIWSLGCVVIEM 1068
>01707
Length = 757
Score = 81.6 bits (200), Expect = 8e-16, Method: Compositional matrix adjust.
Identities = 56/225 (24%), Positives = 112/225 (49%), Gaps = 14/225 (6%)
Frame = +1
Query: 345 LGKGCFGQAIKVTHRETGEVMVMKELIRFDEE--TQRTFLKEVKVMRCLEHPNVLKFIGV 402
+G+G +G K ++ET +++ +K+ + +++ ++ ++E+++++ L+HPN+++ I V
Sbjct: 88 IGEGSYGVVFKCRNKETSQLVAIKKFVESEDDPLIKKIAMREIRMLKQLKHPNLVRLIEV 267
Query: 403 LYKDKRLNFITEYIKGGTLRGIIKS-MDSQYPWSQRVSFAKDIASGMAYLHSMNIIHRDL 461
+ KRL+ + +Y+ L + + P +R+ + +A + + H N IHRD+
Sbjct: 268 FRRKKRLHLVFDYVDHTLLNELDRYPRGLPEPMVKRIIYQTLLA--VNFCHQYNTIHRDV 441
Query: 462 NSHNCLVRENKNVVVADFGLARLMV---DEKTQPEGLRSLKKPDRKKRYTVVGNPYWMAP 518
N L+ V + DFG AR++ DE T V ++ AP
Sbjct: 442 KPENILITRQGQVKLCDFGFARILTGPGDEYTD-----------------YVATRWYRAP 570
Query: 519 EMINGRS-YDEKVDVFSFGIVLCEII-------GRVNADPDYLPR 555
E++ G + Y VDV++ G V E++ GR + D +L R
Sbjct: 571 ELLVGDTQYGPPVDVWAIGCVFAELLTGQALWPGRSDVDQLHLIR 705
>07291
Length = 833
Score = 81.3 bits (199), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 50/178 (28%), Positives = 85/178 (47%), Gaps = 6/178 (3%)
Frame = +1
Query: 436 QRVSFAKDIASGMAYLHSMNIIHRDLNSHNCLVRENKNVVVADFGLARLMVDEKTQPEGL 495
Q + F + IA GMAYL + ++HR+L + NC+V E+ + ++D+G+ + +
Sbjct: 52 QLLDFGRQIADGMAYLQEVKVVHRNLAARNCIVTEDGRLQLSDYGVTGSLFPQ------- 210
Query: 496 RSLKKPDRKKRYTVVGNPY-----WMAPEMINGRSYDEKVDVFSFGIVLCEIIGR-VNAD 549
YT +P WMAPE I+ + K DV++FG+VL E++ R +
Sbjct: 211 ---------SYYTADDSPARDLVKWMAPETIDNFHFSSKSDVWAFGVVLWELLTRGITPY 363
Query: 550 PDYLPRTMDFGLNVRGFLDRYCPPNCPPSFFPITVRCCDLDPEKRPSFVKLEHWLETL 607
PD ++ L + + P P + + C + PE+RP F +L L+T
Sbjct: 364 PDVENSSLLPYLKEGHRMKK--PKQSPEPVYEMMTACWNESPEQRPDFAELNDQLKTF 531
>13592
Length = 980
Score = 80.9 bits (198), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 66/266 (24%), Positives = 115/266 (43%), Gaps = 10/266 (3%)
Frame = +2
Query: 345 LGKGCFGQAIKVTHRETGEVMVMKELIRFDEETQ--RTFLKEVKVMRCLEHPNVLKFIGV 402
+G+G FG+ + TGE+M MKE+ ET+ + +E+K++ ++H N++++ G+
Sbjct: 8 IGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETRALKNVAEELKILEGIKHKNLVRYYGI 187
Query: 403 LYKDKRLNFITEYIKGGTLRGIIKSMDSQYPWSQRVSFAKDIASGMAYLHSMNIIHRDLN 462
+ L E GTL +++ + P + F + SG+A LH I+HRD+
Sbjct: 188 EVHREELLIFMELCSEGTLESLVE-LTGGLPEALSRRFTAQLLSGVAELHKHGIVHRDIK 364
Query: 463 SHNCLVRENKNVV-VADFGLARLMVDEKTQPEGLRSLKKPDRKKRYTVVGNPYWMAPEMI 521
+ N + + N + + DFG A + T P L+ VG +MAPE+
Sbjct: 365 TANIFLVDGSNSLKLGDFGSAVKIQAHTTVPGELQGY-----------VGTQAYMAPEVF 511
Query: 522 ---NGRSYDEKVDVFSFGIVLCEIIGRVNADPDYLPRTMDFGLNVRGFLDRYCPPNCPPS 578
N + D++S G V+ E+ A D + + P P S
Sbjct: 512 TKTNSDGHGRLADIWSVGCVVVEM-----ASGKRPWAQFDSNFQIMFKVGMGEKPQAPES 676
Query: 579 F----FPITVRCCDLDPEKRPSFVKL 600
C DP++R S ++L
Sbjct: 677 LSQEGHDFIDHCLQHDPKQRLSAIEL 754
>01756
Length = 1858
Score = 79.7 bits (195), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 56/213 (26%), Positives = 104/213 (48%), Gaps = 12/213 (5%)
Frame = -3
Query: 345 LGKGCFGQAIKVTHRETGEVMVMKELIRFDEETQR---TFLKEVKVMRCLEHPNVLKFIG 401
+G+G FG+ K ++T +V+ MK+++ D E + T L+E+K+++ L H NV+ I
Sbjct: 1718 IGQGTFGEVFKARCKKTKQVVAMKKVL-MDNEKEGFPITALREIKILQLLNHENVVDLIE 1542
Query: 402 V-------LYKDKRLNFITEYIKGGTLRGIIKSMDSQYPWSQRVSFAKDIASGMAYLHSM 454
+ + K + ++ L G++ +M + + K + +G+ Y+H
Sbjct: 1541 ICSTKATSANRYKSMFYLVFEFCEHDLAGLLSNMSVVFNLPEIKEVMKQLMNGLYYIHRN 1362
Query: 455 NIIHRDLNSHNCLVRENKNVVVADFGLARLMVDEKTQPEGLRSLKKPDRKKRYT-VVGNP 513
I+HRD+ + N L+ + + +ADFGLAR QP RYT V
Sbjct: 1361 KILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQP------------NRYTNRVVTL 1218
Query: 514 YWMAPEMING-RSYDEKVDVFSFGIVLCEIIGR 545
++ PE++ G R+Y +D + G ++ E+ R
Sbjct: 1217 WYRPPELLLGDRNYSTAIDQWGAGCIMAEMWTR 1119
>14126
Length = 1265
Score = 74.7 bits (182), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 57/213 (26%), Positives = 97/213 (45%), Gaps = 11/213 (5%)
Frame = +3
Query: 344 VLGKGCFGQAIKVTH-RETGEVMVMKE--LIRFDEETQRTFLKEVKVMRCLE---HPNVL 397
V+G G +G K R GE + MK L +E ++E+ +++ LE HPNV+
Sbjct: 210 VIGNGAYGTVYKARDLRNQGEFVAMKRIRLNNTEEGMPMMAIREISMLKQLEQYEHPNVV 389
Query: 398 KFIGVLY-----KDKRLNFITEYIKGGTLRGIIKSMDSQYPWSQRVSFAKDIASGMAYLH 452
+ + V + ++ RLN + EYI+ + K + + +G+ +LH
Sbjct: 390 RLLDVSHNTITDREIRLNLVFEYIEHDLATYLAKCPSPGLGPDRIKDLMLQLLNGVDFLH 569
Query: 453 SMNIIHRDLNSHNCLVRENKNVVVADFGLARLMVDEKTQPEGLRSLKKPDRKKRYTVVGN 512
S I+HRDL N L+ ++ + +ADFGLAR+ TVV
Sbjct: 570 SNRIVHRDLKPQNLLISKDGRLKLADFGLARIYSFHMALT---------------TVVVT 704
Query: 513 PYWMAPEMINGRSYDEKVDVFSFGIVLCEIIGR 545
++ +PE++ Y VD++S G + E+ R
Sbjct: 705 LWYRSPEVLMQAEYGTSVDIWSCGCIFAELFTR 803
>00715
Length = 1788
Score = 72.8 bits (177), Expect = 5e-13, Method: Compositional matrix adjust.
Identities = 54/205 (26%), Positives = 95/205 (46%), Gaps = 12/205 (5%)
Frame = +1
Query: 353 AIKVTHRETGEVMVMKELIRFDEETQRTFLKEVKVMRC-LEHPNVLKFIGV--LYKDKRL 409
A+K+ H+ + +++ ++ E+ RC L H NV+ +G L++ +
Sbjct: 10 AVKIYHKRSSNPRALRQ----------SYSNELLAFRCGLRHVNVVSILGATSLHRFEDG 159
Query: 410 NFIT-EYIKGGTLRGIIKSMDSQYPWSQRVSFAKDIASGMAYLHSMNIIHRDLNSHNCLV 468
++ EY+ L+ I+ S R+S A +A G+ YLHS+NI+H DL NCL+
Sbjct: 160 AWLAMEYVGPLNLQTILNDHQQDIDSSMRLSLALQMARGLHYLHSINIVHLDLKPANCLL 339
Query: 469 RENKNVVVADFG----LARLMVDEKTQPEGLR----SLKKPDRKKRYTVVGNPYWMAPEM 520
+ + +ADFG L +D + G+ L + + G + APE+
Sbjct: 340 TRDLKLRIADFGCCHQLTPTGLDMGEREGGMAGNELELTPVQGAWKNELAGTLAYRAPEL 519
Query: 521 INGRSYDEKVDVFSFGIVLCEIIGR 545
+ G + DV+S GI L ++ R
Sbjct: 520 LKGLQPSVRSDVYSLGITLWQMCTR 594
>19301
Length = 712
Score = 71.6 bits (174), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 52/140 (37%), Positives = 75/140 (53%)
Frame = +2
Query: 343 EVLGKGCFGQAIKVTHRETGEVMVMKELIRFDEETQRTFLKEVKVMRCLEHPNVLKFIGV 402
E LG G G A+ + EV V K +R +ET +++ +R L HPN++ F GV
Sbjct: 323 EWLGSGAQG-AVFLGKLCAEEVAVKK--VRDIKET------DIRNLRKLNHPNIISFKGV 475
Query: 403 LYKDKRLNFITEYIKGGTLRGIIKSMDSQYPWSQRVSFAKDIASGMAYLHSMNIIHRDLN 462
+ I EY G L +++ + P + + ++K IASGM YLHS IIHRDL
Sbjct: 476 CTQAPCYCIIMEYCPYGQLYEVLRD-GKEIPPALVLDWSKQIASGMNYLHSHKIIHRDLK 652
Query: 463 SHNCLVRENKNVVVADFGLA 482
S N LV +N V ++DFG +
Sbjct: 653 SPNVLVAKNDVVKISDFGTS 712
>07940
Length = 1336
Score = 71.2 bits (173), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 42/107 (39%), Positives = 58/107 (54%), Gaps = 1/107 (0%)
Frame = -3
Query: 438 VSFAKDIASGMAYLHSMNIIHRDLNSHNCLVRENKNVVVADFGLARLMVDEKTQPEGLRS 497
+S+A +A GM YL S IHRDL + N LV E + +ADFGL R+
Sbjct: 338 ISYAYQVARGMEYLASKQCIHRDLAARNVLVAEEYVLKIADFGLT-------------RN 198
Query: 498 LKKPDRKKRYTVVGNPY-WMAPEMINGRSYDEKVDVFSFGIVLCEII 543
L++ D ++ T P WMAPE + R Y K DV+S+G++L EI
Sbjct: 197 LQQFDYYRKTTDGRLPVKWMAPEALFDRKYTSKSDVWSYGVLLWEIF 57
>19094
Length = 898
Score = 68.9 bits (167), Expect = 7e-12, Method: Compositional matrix adjust.
Identities = 37/96 (38%), Positives = 50/96 (52%)
Frame = +1
Query: 447 GMAYLHSMNIIHRDLNSHNCLVRENKNVVVADFGLARLMVDEKTQPEGLRSLKKPDRKKR 506
G+ YLHS IHRD+ + N L+ + +ADFG+A + D KR
Sbjct: 94 GL*YLHSRRKIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMA--------------KR 231
Query: 507 YTVVGNPYWMAPEMINGRSYDEKVDVFSFGIVLCEI 542
TV+G PYWMAPE+I YD D++S GI E+
Sbjct: 232 NTVIGTPYWMAPEVIQEIGYDCVADIWSLGITALEM 339
>00392
Length = 668
Score = 68.6 bits (166), Expect = 7e-12, Method: Compositional matrix adjust.
Identities = 50/179 (27%), Positives = 90/179 (50%), Gaps = 8/179 (4%)
Frame = +3
Query: 372 RFDEETQRTFLKEVKVMRCLEHPNVLKFIGVLYKDKRLN-----FITEYIKGGTLRGIIK 426
++++ ++ F +E ++++ L+HPN+++F + N +TE + GTL+ +K
Sbjct: 45 KWNKAERQRFKEEAEMLKELQHPNIVRFFDYWEEHNHRNRKVIILVTELMTSGTLKTYLK 224
Query: 427 SMDSQYPWSQRVSFAKDIASGMAYLHSMN--IIHRDLNSHNCLVR-ENKNVVVADFGLAR 483
+ ++ + + G+ +LH+ +IHRDL N + +V + D GLA
Sbjct: 225 RFKKPNVKILK-NWCRQVLKGLYFLHTRTPPVIHRDLKCDNIFITGPTGSVKIGDLGLAT 401
Query: 484 LMVDEKTQPEGLRSLKKPDRKKRYTVVGNPYWMAPEMINGRSYDEKVDVFSFGIVLCEI 542
L K Q S K +V+G P +MAPEM YDE VDV++FG+ + E+
Sbjct: 402 L----KNQ-----SFAK-------SVIGTPEFMAPEMYE-EHYDEAVDVYAFGMCMLEM 527
>03240
Length = 1683
Score = 67.8 bits (164), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 60/238 (25%), Positives = 107/238 (44%), Gaps = 37/238 (15%)
Frame = -3
Query: 343 EVLGKGCFGQAIKVTHRETGEVMVMKELIRFDEETQRTFLKEVKVMRCL----EHPNVLK 398
+ LG G FG+ +TG + MK L R + +R + VK R + ++ V+K
Sbjct: 1273 KTLGVGAFGEVSLCRKNDTGMLYAMKTL-RKSDVLKRNQVAHVKAERDILAEADNEWVVK 1097
Query: 399 FIGVLYKDKRLNFITEYIKGGTLRGIIKSMDSQYPWSQRVSFAKDIASGMAYLHSMNIIH 458
L F+ +Y+ GG L G++ M+ R + ++ + +H M IH
Sbjct: 1096 LYYSFQDHNYLYFVMDYVPGGDLMGLLIRMEILDEPLARF-YVAELVQAIESVHRMGFIH 920
Query: 459 RDLNSHNCLVRENKNVVVADFGL--------------------------ARLMVDEKTQP 492
RD+ N L+ N ++ + DFGL + +DE+ Q
Sbjct: 919 RDIKPDNILIDRNGHIKLTDFGLCTGFRWTHNSKYYQRDGTHARQDSMEVKCQLDEQCQC 740
Query: 493 EGLRSLKKPDRKKR------YTVVGNPYWMAPEMINGR-SYDEKVDVFSFGIVLCEII 543
E L+ L++ R+KR +++VG P ++APE+++ Y D +S G++L E++
Sbjct: 739 EILKPLER--RRKREQRCLAHSLVGTPNYIAPEVLSRLGGYTSVCDWWSVGVILFEML 572
>13212
Length = 1067
Score = 65.1 bits (157), Expect = 8e-11, Method: Compositional matrix adjust.
Identities = 38/129 (29%), Positives = 64/129 (49%), Gaps = 5/129 (3%)
Frame = -1
Query: 419 GTLRGIIKSMDSQYPWSQRVSFAKDIASGMAYLHSMNIIHRDLNSHNCLVRENKNVVVAD 478
G L I+ ++ +Q ++ + +LH ++IHRD+ + N L+ + V +AD
Sbjct: 1028 GALDSIMVDLEKPMTEAQICYVCHEMCMALDFLHRHHVIHRDIKAGNVLLTIDGEVKLAD 849
Query: 479 FGLARLMVDEKTQPEGLRSLKKPDRKKRYTVVGNPYWMAPEMI-----NGRSYDEKVDVF 533
FG++ + TQ ++KR T +G PYWMAPE++ YD K D++
Sbjct: 848 FGVSA----KNTQ----------TQQKRDTFIGTPYWMAPEVVLCETLKDTPYDFKADIW 711
Query: 534 SFGIVLCEI 542
S G+ L E
Sbjct: 710 SLGVTLIEF 684
>01966
Length = 1735
Score = 65.1 bits (157), Expect = 9e-11, Method: Compositional matrix adjust.
Identities = 46/170 (27%), Positives = 83/170 (48%), Gaps = 4/170 (2%)
Frame = -1
Query: 358 HRETGEVMVMKEL-IRFDEE-TQRTFLKEVKVMRCLEHPNVLKFIGVLYKDKRLNFITEY 415
HR TG + MK++ +R E+ + ++E+ ++R L H N++ V+ +D+RL + E+
Sbjct: 1648 HRATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTNIVCLEDVIMEDERLFLVFEF 1469
Query: 416 IKGGTLRGIIKSMDSQYPWSQRV--SFAKDIASGMAYLHSMNIIHRDLNSHNCLVRENKN 473
+ L+ I +R+ S+ I +G+ + H I+HRDL N L+
Sbjct: 1468 L-SMDLKMYIDKFPEGVVLDRRLVKSYVFQIVTGINFCHQRRIVHRDLKPQNLLINHTGA 1292
Query: 474 VVVADFGLARLMVDEKTQPEGLRSLKKPDRKKRYTVVGNPYWMAPEMING 523
+ +ADFG+A R+ P R + VV ++ APE++ G
Sbjct: 1291 IKIADFGMA-------------RTFALPVRAYTHEVV-TLWYRAPEILMG 1184
>09606
Length = 1300
Score = 64.3 bits (155), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 61/241 (25%), Positives = 100/241 (41%), Gaps = 15/241 (6%)
Frame = -3
Query: 333 IFRPSDLIHGEVLGKGCFGQAIKVTHRETGEVMVMKELIRFDEETQR-TFLKEVKVMRCL 391
I R + + E LGKG +I R G + + I E+ +R V++ +
Sbjct: 1127 ITRMENFVLYEELGKG--EHSIIYKGRRKGTINFVA--IHCIEKCKRPEVTNTVRMTHDI 960
Query: 392 EHPNVLKFIGVLYKDKRLNFITEYIKGGTLRGIIKSMDSQYPWSQRVSFAKDIASGMAYL 451
HPNV++F L + E GG+L I+ + D P + F + +G+ Y+
Sbjct: 959 SHPNVVQFHEWYETSNHLWLVVELCTGGSLADIL-AQDHHLPETSIRDFGIHLVTGLHYI 783
Query: 452 HSMNIIHRDLNSHNCLVRENKNVVVADFGLARLMVDEKTQPEGLRSL------------- 498
HS+ I+ DL L+ + + ADFGL+ K + E L L
Sbjct: 782 HSLGILFHDLRPSKVLLDTSGVLKFADFGLS------KVEGENLEELFFKFAEAGDQWNI 621
Query: 499 -KKPDRKKRYTVVGNPYWMAPEMINGRSYDEKVDVFSFGIVLCEIIGRVNADPDYLPRTM 557
+ K+ G+P +MAPE+ G D+++ G V E+ + P +L T
Sbjct: 620 QSAEEMMKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMF---SGHPPFLGETY 450
Query: 558 D 558
D
Sbjct: 449 D 447
>27546
Length = 426
Score = 64.3 bits (155), Expect = 1e-10, Method: Composition-based stats.
Identities = 34/110 (30%), Positives = 59/110 (53%)
Frame = -1
Query: 378 QRTFLKEVKVMRCLEHPNVLKFIGVLYKDKRLNFITEYIKGGTLRGIIKSMDSQYPWSQR 437
++ F +E++++ L+HPN+++ +L + ++ Y + G + IK +
Sbjct: 348 KKFFPRELEILTRLDHPNIIQIHSILQRGPKIFIFMRYAEKGDMLSHIKKTGPIDEAQTK 169
Query: 438 VSFAKDIASGMAYLHSMNIIHRDLNSHNCLVRENKNVVVADFGLARLMVD 487
V F + +A + YLHS +I HRDL N L+ + NV +ADFG AR D
Sbjct: 168 VWFFQ-MAKALQYLHSHDIAHRDLKCENILLSKRLNVKIADFGFARYCRD 22
>04591
Length = 1117
Score = 64.3 bits (155), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 43/175 (24%), Positives = 87/175 (49%), Gaps = 9/175 (5%)
Frame = -2
Query: 380 TFLKEVKVMRCLEHPNVLKFIGVL------YKDKRLNF--ITEYIKGGTLRGIIKSMDSQ 431
T L+E+K+++ LEH NV++ + Y + F I EY L G++ ++ +
Sbjct: 1083 TALREIKILQQLEHENVVQLQEICHTQAGPYNRYKSTFYLIFEYCDY-DLAGLLNNLRVK 907
Query: 432 YPWSQRVSFAKDIASGMAYLHSMNIIHRDLNSHNCLVRENKNVVVADFGLARLMVDEKTQ 491
+ + + + + +G+ Y+H+ I+HRD+ + N L+ + + +ADFGL+R V K
Sbjct: 906 FSLADKKNLMSQLLNGLFYIHTKQILHRDIKAANILLTRDGVLKLADFGLSRPWVKSKRL 727
Query: 492 PEGLRSLKKPDRKKRYTVVGNPYWMAPEMING-RSYDEKVDVFSFGIVLCEIIGR 545
+ +L ++ PE++ G R Y ++D++ G ++ E+ R
Sbjct: 726 TNRVVTL---------------WYRPPELLLGEREYGPEIDMWGVGCIMAEMWSR 607
>07836
Length = 1478
Score = 62.8 bits (151), Expect = 5e-10, Method: Compositional matrix adjust.
Identities = 53/192 (27%), Positives = 95/192 (49%), Gaps = 22/192 (11%)
Frame = -1
Query: 373 FDEETQRTFLKEVKVMRC--LEHPNVLKFIGVLYKDK----RLNFITEYIKGGTLRGIIK 426
F + ++ +E ++ + L H N+L FI K +L IT+Y + G+L +
Sbjct: 1454 FFTTEEASWFRETELYQTVLLRHENILGFIAADIKGTGSWTQLFLITDYHENGSLHDYLL 1275
Query: 427 S--MDSQYPWSQRVSFAKDIASGMAYLH--------SMNIIHRDLNSHNCLVRENKNVVV 476
S +DS S+ ++ A G+A+LH I HRD+ S N LV++N +
Sbjct: 1274 SRVLDS----SEMLALAHSAICGLAHLHIEIFGTRGKPAIAHRDIKSKNILVKKNGTCCI 1107
Query: 477 ADFGLARLMVDEKTQPEGLRSLKKPDRKKRYTVVGNPYWMAPE----MINGRSYD--EKV 530
AD GLA + E + + P+ ++ G +MAPE ++N +++D ++
Sbjct: 1106 ADLGLAVRYISESNEVD-----VAPNPRQ-----GTKRYMAPEVLEMLLNVKNFDAFKQA 957
Query: 531 DVFSFGIVLCEI 542
D+++FG+V+ EI
Sbjct: 956 DMYAFGLVMWEI 921
>17300
Length = 480
Score = 62.4 bits (150), Expect = 5e-10, Method: Composition-based stats.
Identities = 39/100 (39%), Positives = 52/100 (52%)
Frame = +1
Query: 444 IASGMAYLHSMNIIHRDLNSHNCLVRENKNVVVADFGLARLMVDEKTQPEGLRSLKKPDR 503
I+SGM L M +HRDL + N LV E VADFGL+R + + T EG + K
Sbjct: 1 ISSGMGXLADMGYVHRDLAARNILVNEILVCKVADFGLSREIESDTT--EGAYTTKGGKI 174
Query: 504 KKRYTVVGNPYWMAPEMINGRSYDEKVDVFSFGIVLCEII 543
R W APE I R + DV+SFG+V+ E++
Sbjct: 175 PVR--------WTAPEAIAYRKFTSASDVWSFGVVMWEVM 270
>08294
Length = 1849
Score = 62.0 bits (149), Expect = 7e-10, Method: Compositional matrix adjust.
Identities = 55/224 (24%), Positives = 99/224 (44%), Gaps = 17/224 (7%)
Frame = +2
Query: 394 PNVLKFIGVLYKDKRLNFITEYIKGGTLRGII--------KSMDSQYP---WSQRVSFAK 442
PN++ F+GV + + ITEY G L+ + + ++ P SQ++ +
Sbjct: 887 PNIVHFMGVCREAEPHFLITEYCDWGDLKQFLLATRNDNGRGRGTRVPALALSQKLGMGQ 1066
Query: 443 DIASGMAYLHSMNIIHRDLNSHNCLVRENKNVVVADFGLARLMVDEKTQPEGLRSLKKPD 502
+A+GM L + ++H DL + N L+ + VA L+ + + P L P
Sbjct: 1067 QVAAGMEALSNQGLVHGDLAARNVLLTSRMQLKVARPALSGDVYASEYYP--LHQRLVPL 1240
Query: 503 RKKRYTVVGNPYWMAPEMINGRSYDEKVDVFSFGIVLCEIIG------RVNADPDYLPRT 556
R W+ PE + S DV++FG+ L E++ R+ +D + L R+
Sbjct: 1241 R-----------WLPPEGVLEDSATTCGDVWAFGVFLWEVLQLADLPYRLMSDEEVL-RS 1384
Query: 557 MDFGLNVRGFLDRYCPPNCPPSFFPITVRCCDLDPEKRPSFVKL 600
+ + + LD P+ PP+ + RC P +RP F ++
Sbjct: 1385 LQ---HSQAALDS---PDAPPALLSLLQRCTAQQPSQRPPFSEI 1498
>12672
Length = 773
Score = 61.6 bits (148), Expect = 9e-10, Method: Compositional matrix adjust.
Identities = 48/180 (26%), Positives = 78/180 (43%), Gaps = 12/180 (6%)
Frame = +3
Query: 440 FAKDIASGMAYLHSMNIIHRDLNSHNCLVRENKNVVVADFGLARLMVDEKTQPEGLRSLK 499
K ASG+ YL+ +HRD+ + N L+ V DF + P G +
Sbjct: 6 IVKGTASGIQYLNDNGHVHRDIKTANILLDSEYTAKVGDFATVV------SAPSG----E 155
Query: 500 KPDRKKRYTVVGNPYWMAPEMINGRSYDEKVDVFSFGIVLCEII-GRVNADPDYLPRTMD 558
+ V+G ++APE I+ K+D +SFG+VL E+I G V D RT+
Sbjct: 156 GKTVQNASVVIGTAAYLAPEAIH-FDVSTKLDSYSFGVVLLEVITGLVAQDYSREERTLS 332
Query: 559 FGL--------NVRGFLDRYC---PPNCPPSFFPITVRCCDLDPEKRPSFVKLEHWLETL 607
+ + F+D+ P + I++RC +L ++RP+ + LE L
Sbjct: 333 SHIMENVEEPEEIHDFVDQSAGTWPDGAVDKLYDISMRCLNLSKKQRPNVKDIRPELEEL 512
>17975
Length = 449
Score = 61.2 bits (147), Expect = 1e-09, Method: Composition-based stats.
Identities = 35/135 (25%), Positives = 65/135 (48%), Gaps = 3/135 (2%)
Frame = +3
Query: 358 HRETGEVMVMKEL--IRFDEETQRTFLKEVKVMRCLEHPNVLKFIGVLYKDKRLNFITEY 415
H TGE + +K + + DE ++ +EV+ M+ ++HPNV++ V+ +L I E
Sbjct: 30 HVFTGEKVAVKVIDKTKLDEVSRSHLFQEVRCMKLVQHPNVVRLYEVIDTQTKLYLILEL 209
Query: 416 IKGGTLRGIIKSMDSQYPWSQRVSFAKDIASGMAYLHSMNIIHRDLNSHNCLVRENKNVV 475
GG + I + + I ++Y H ++++HRDL N + E +V
Sbjct: 210 GDGGDMYDYIMRHSGGLEEKLAKRYFRQIVEAISYCHKLHVVHRDLKPENVVFFEKPGLV 389
Query: 476 -VADFGLARLMVDEK 489
+ DFG + ++ K
Sbjct: 390 KLTDFGFSTCLLQAK 434
>20640
Length = 1492
Score = 60.8 bits (146), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 48/151 (31%), Positives = 63/151 (41%)
Frame = +1
Query: 457 IHRDLNSHNCLVRENKNVVVADFGLARLMVDEKTQPEGLRSLKKPDRKKRYTVVGNPYWM 516
+HRDL + NCLV + V ++DFGLAR V G P R WM
Sbjct: 10 VHRDLATRNCLVGHDLVVKISDFGLAR-SVHSVDYYRGSEHDAIPIR-----------WM 153
Query: 517 APEMINGRSYDEKVDVFSFGIVLCEIIGRVNADPDYLPRTMDFGLNVRGFLDRYCPPNCP 576
E I + + DV+SFG+VL EI P Y + V+ CP P
Sbjct: 154 PLEAILYNKFSTQSDVWSFGVVLWEIFA-FALQPYYGLTHEEVVRFVKEGKVLACPERTP 330
Query: 577 PSFFPITVRCCDLDPEKRPSFVKLEHWLETL 607
P + + +C P RPSF L LE +
Sbjct: 331 PPMYELMKQCWHRRPATRPSFHTLHKTLENM 423
>11928
Length = 1623
Score = 60.8 bits (146), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 41/121 (33%), Positives = 58/121 (47%), Gaps = 1/121 (0%)
Frame = -2
Query: 24 VCASCGQRIYDGQYLQALNADWHADCFRCCDCSASL-SHQYYEKDGQLFCKKDYWARYGE 82
VCA+C + I GQ + AL WH + F C C L + +YE+D +C+ DY +
Sbjct: 1601 VCAACNKPIV-GQVIAALGRTWHVEHFVCAHCEQPLGTSNFYERDSVAYCEVDYHNLFAP 1425
Query: 83 SCHGCSEQITKGLVMVAGELKYHPECFICLTCGTFIGDGDTYTLVEHSKLYCGHCYYQTV 142
C C+ I + A E +HPE F C CG GD D + ++ K YC Y+Q
Sbjct: 1424 RCAYCNGPIVDKCI-TALEKMWHPEHFFCAQCGRQFGDEDFHE--KNGKAYCRDDYFQMF 1254
Query: 143 V 143
Sbjct: 1253 A 1251
Score = 58.9 bits (141), Expect = 6e-09, Method: Compositional matrix adjust.
Identities = 33/103 (32%), Positives = 50/103 (48%), Gaps = 1/103 (0%)
Frame = -2
Query: 23 PVCASCGQRIYDGQYLQALNADWHADCFRCCDCSASLSHQ-YYEKDGQLFCKKDYWARYG 81
P CA C I D + + AL WH + F C C + ++EK+G+ +C+ DY+ +
Sbjct: 1427 PRCAYCNGPIVD-KCITALEKMWHPEHFFCAQCGRQFGDEDFHEKNGKAYCRDDYFQMFA 1251
Query: 82 ESCHGCSEQITKGLVMVAGELKYHPECFICLTCGTFIGDGDTY 124
C GC I + + A ++HP+CF C C G G Y
Sbjct: 1250 PKCGGCGMPIMENYI-SALNRQWHPQCFCCWECQAPFGTGSFY 1125
>30755
Length = 1137
Score = 60.8 bits (146), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 40/118 (33%), Positives = 62/118 (52%), Gaps = 4/118 (3%)
Frame = +2
Query: 440 FAKDIASGMAYLHSMNIIHRDLNSHNCLVRENKNVVVADFGLARLMVDEKTQPEGLRSLK 499
+ +I S + YLHS II+RDL N L+ ++ ++ VADFGL + + R+ K
Sbjct: 47 YGAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCKEDITYG------RTTK 208
Query: 500 KPDRKKRYTVVGNPYWMAPEMINGRSYDEKVDVFSFGIVLCEII-GRV---NADPDYL 553
T G P ++APE+++ Y VD + G+V+ E+I GR+ N D D L
Sbjct: 209 --------TFCGTPEYLAPEVLDDNDYGRAVDWWGTGVVMYEMICGRLPFYNRDHDVL 358
>13066
Length = 551
Score = 60.5 bits (145), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 41/161 (25%), Positives = 76/161 (47%), Gaps = 1/161 (0%)
Frame = +3
Query: 377 TQRTFLKEVKVMRCLEHPNVLKFIGVLYKDKRLNFITEYIKGGTLRGIIKSMDSQYPWSQ 436
++ F +E+ ++ L+HP +++ +L + + + + G L I+ +
Sbjct: 105 VEKFFPRELDLLTKLDHPYIIQIHSILQRXPKNFIFMRFAERGDLLTYIQEVGFVKEKQA 284
Query: 437 RVSFAKDIASGMAYLHSMNIIHRDLNSHNCLVRENKNVVVADFGLARLMVDEKTQPEGLR 496
++ F + + + + YLHS ++ HRDL N L+ + NV +ADFG A + E + R
Sbjct: 285 KIWFYQ-MTTALNYLHSYDVAHRDLKCENILLSSHFNVKLADFGFACACITESGEKYMSR 461
Query: 497 SLKKPDRKKRYTVVGNPYWMAPEMINGRSYDEKV-DVFSFG 536
T G+ + APE++ G Y KV D +S G
Sbjct: 462 -----------TYCGSAAYAAPEIVYGAPYAPKVADAWSLG 551
>29581
Length = 1278
Score = 60.1 bits (144), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 45/157 (28%), Positives = 76/157 (48%), Gaps = 3/157 (1%)
Frame = -2
Query: 391 LEHPNVLKFIGVLYKDK--RLNFITEYIKGGTLRGIIKSMDSQYPWSQRVSFAKDIASGM 448
L H N+++ V+ L + EY + L ++ +M + + SQ + G+
Sbjct: 1184 LRHQNIVQLQEVVVGKSLDSLFLVMEYCEQD-LASLLDNMPAPFSESQVKCIVLQLLKGL 1008
Query: 449 AYLHSMNIIHRDLNSHNCLVRENKNVVVADFGLARLMVDEKTQPEGLRSLKKPDRKKRYT 508
YLH IIHRDL N L+ + V +ADFGLA R+ KP +
Sbjct: 1007 RYLHEAFIIHRDLKVSNLLMTDKGCVKIADFGLA-------------RNYGKPQKPMTPK 867
Query: 509 VVGNPYWMAPEMING-RSYDEKVDVFSFGIVLCEIIG 544
VV ++ APE++ G +++ +D++S G +L E++G
Sbjct: 866 VV-TLWYRAPELLFGSKTHSTAIDMWSAGCILGELLG 759
>07833
Length = 1504
Score = 60.1 bits (144), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 63/239 (26%), Positives = 103/239 (43%), Gaps = 9/239 (3%)
Frame = -3
Query: 379 RTFLKEVKVMRCLEHPNVLKFIGVLYKDKRLNFITEYIKGGTLRGIIKSMDS-QYPWSQR 437
R F++E +R HPNVL + + L I++++ G+L + +Q
Sbjct: 1484 RDFMEEFPRLRIFNHPNVLPVLACCNQPPNLVLISQFMPFGSLYNTLHGESGIVVDQNQS 1305
Query: 438 VSFAKDIASGMAYLHSM--NIIHRDLNSHNCLVREN--KNVVVADFGLARLMVDEKTQPE 493
+ FA DIA GM +LHSM I + L S + ++ E+ + +AD+ + EK +
Sbjct: 1304 LRFAMDIARGMEFLHSMEPTIPNFLLTSKHVMIDEDLTARINMADYCFS---FHEKGK-- 1140
Query: 494 GLRSLKKPDRKKRYTVVGNPYWMAPEMINGRSYD---EKVDVFSFGIVLCEIIGRVNADP 550
V +P WMAPE + R D D++SF I++ E+ R P
Sbjct: 1139 ----------------VYSPAWMAPEALQRRPDDINTRAADMWSFAILMWELETR--EVP 1014
Query: 551 DYLPRTMDFGLNVR-GFLDRYCPPNCPPSFFPITVRCCDLDPEKRPSFVKLEHWLETLR 608
+M+ G+ V L PP + C + +P KRP F + LE ++
Sbjct: 1013 FAELSSMEVGMKVALEGLRISIPPGISLHMSRLIKICMNEEPGKRPRFDMIIPILEKMK 837
>21079
Length = 878
Score = 59.7 bits (143), Expect = 4e-09, Method: Compositional matrix adjust.
Identities = 43/153 (28%), Positives = 70/153 (45%), Gaps = 2/153 (1%)
Frame = +1
Query: 393 HPNVLKFIGVLYKDKRLNFITEYIKGGTLRGIIKSMDSQYPWSQRVSFAKDIASGMAYLH 452
HP +L + + + E++ G L + D V F + I SG+ Y+H
Sbjct: 1 HPKLLMLWDAFEAPRTMVLVMEFVGAGELFERVIRDDFVLTERDCVHFVRQICSGVGYMH 180
Query: 453 SMNIIHRDLNSHNCL-VRENKNVV-VADFGLARLMVDEKTQPEGLRSLKKPDRKKRYTVV 510
+ +I+H DL N L V +N N + + DFGLAR KP + +
Sbjct: 181 TQSILHLDLKPENVLCVSDNSNQIKIIDFGLAR--------------FYKPGDSLQ-VLF 315
Query: 511 GNPYWMAPEMINGRSYDEKVDVFSFGIVLCEII 543
G P ++APE++N + D++S G V+C I+
Sbjct: 316 GTPEFIAPEVVNYDEINFTTDMWSIG-VICYIL 411
>14477
Length = 493
Score = 59.7 bits (143), Expect = 4e-09, Method: Composition-based stats.
Identities = 38/148 (25%), Positives = 74/148 (50%), Gaps = 4/148 (2%)
Frame = -1
Query: 345 LGKGCFGQAIK-VTHRETGEVMVMKELIR---FDEETQRTFLKEVKVMRCLEHPNVLKFI 400
LG G FG +K V + E+ V ++++ D Q +KE +VM+ ++H ++++ I
Sbjct: 466 LGAGNFGSVMKGVCRLDDREIPVAIKVLKNADLDPSVQSELIKEAEVMKKMDHMHIVRLI 287
Query: 401 GVLYKDKRLNFITEYIKGGTLRGIIKSMDSQYPWSQRVSFAKDIASGMAYLHSMNIIHRD 460
G L + + + + E K G L + + P + ++ GM YL + +HRD
Sbjct: 286 G-LCEGETMMLVLELAKLGPLNKFLPK-NKHLPLWNILELMWQVSQGMEYLEANKFVHRD 113
Query: 461 LNSHNCLVRENKNVVVADFGLARLMVDE 488
L + N L+ + ++DFG+++ + E
Sbjct: 112 LAARNILLCDEHFAKISDFGMSKTLSRE 29
>18484
Length = 635
Score = 58.5 bits (140), Expect = 8e-09, Method: Composition-based stats.
Identities = 32/105 (30%), Positives = 58/105 (55%)
Frame = +1
Query: 440 FAKDIASGMAYLHSMNIIHRDLNSHNCLVRENKNVVVADFGLARLMVDEKTQPEGLRSLK 499
+A +IA G+ +LH II+RDL N ++ ++ +ADFG+ + EG+
Sbjct: 58 YAAEIAVGLFFLHDQGIIYRDLKLDNVMLDSEGHIKIADFGMCK---------EGMTG-- 204
Query: 500 KPDRKKRYTVVGNPYWMAPEMINGRSYDEKVDVFSFGIVLCEIIG 544
D R T G P ++APE++ + Y + VD +++G++L E++
Sbjct: 205 --DATTR-TFCGTPDYIAPEIVLYQPYSKSVDWWAYGVLLFEMLA 330
>26560
Length = 398
Score = 58.2 bits (139), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 33/105 (31%), Positives = 57/105 (54%), Gaps = 1/105 (0%)
Frame = -1
Query: 440 FAKDIASGMAYLHSMNIIHRDLNSHNCLVRENKNVVVADFGLARLMVDEKTQPEGLRSLK 499
+A ++ G+ ++HS +++RDL N L+ EN +V ++D GLA
Sbjct: 341 YAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGLA----------------C 210
Query: 500 KPDRKKRYTVVGNPYWMAPE-MINGRSYDEKVDVFSFGIVLCEII 543
+K+ + VG +MAPE ++ G+SYD D FSFG +L +++
Sbjct: 209 DFSKKRPHASVGTHGYMAPEVLMKGQSYDSSADWFSFGCMLYKLL 75
>17253
Length = 483
Score = 57.8 bits (138), Expect = 1e-08, Method: Composition-based stats.
Identities = 37/120 (30%), Positives = 59/120 (49%), Gaps = 12/120 (10%)
Frame = -1
Query: 381 FLKEVKVMRCL-EHPNVLKFIGVLYKDKRLNFITEYIKGGTLRGIIK-----------SM 428
FL+E+ +MR L HPNV+ F+G + E+ G L ++ S
Sbjct: 408 FLRELSIMRKLPRHPNVVSFMGCCTMSDPALILMEFCCHGDLLSFLRKRRPDRTVFLTST 229
Query: 429 DSQYPWSQRVSFAKDIASGMAYLHSMNIIHRDLNSHNCLVRENKNVVVADFGLARLMVDE 488
+ SFA +A GMA++ + I+HRD+ + N L+ E V+DFGL+R + D+
Sbjct: 228 ANDLTARDFFSFALHVARGMAHVANNKIVHRDVAARNVLISERNVCKVSDFGLSRRVGDQ 49
>15910
Length = 1361
Score = 57.4 bits (137), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 35/111 (31%), Positives = 56/111 (50%), Gaps = 3/111 (2%)
Frame = +2
Query: 431 QYPWSQRVSFAKDIASGMAYLHSMNIIHRDLNSHNCL---VRENKNVVVADFGLARLMVD 487
QY DI G+ Y+H+ ++HRDL N L + ++ + +ADFGL+R++
Sbjct: 452 QYTEKDAARAISDILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLADFGLSRII-- 625
Query: 488 EKTQPEGLRSLKKPDRKKRYTVVGNPYWMAPEMINGRSYDEKVDVFSFGIV 538
+PE S TV G P + APE++ G Y VD++S G++
Sbjct: 626 ---EPEVQMS----------TVCGTPGYCAPEVLKGDKYTPSVDMWSVGVI 739
>19761
Length = 473
Score = 55.8 bits (133), Expect = 6e-08, Method: Compositional matrix adjust.
Identities = 34/114 (29%), Positives = 57/114 (50%), Gaps = 2/114 (1%)
Frame = -3
Query: 438 VSFAKDIASGMAYLHSMN--IIHRDLNSHNCLVRENKNVVVADFGLARLMVDEKTQPEGL 495
V + AS + Y+H+ I+HRDL N V E +V + D GLAR + T P
Sbjct: 414 VCWLMQTASALNYMHTHTPVILHRDLKPQNIYVTEKGDVRLGDLGLARKL----TGPADF 247
Query: 496 RSLKKPDRKKRYTVVGNPYWMAPEMINGRSYDEKVDVFSFGIVLCEIIGRVNAD 549
+ + VG +++PE+++ + Y+ K D++S G V +I G+ +D
Sbjct: 246 AT----------SQVGTIMYLSPEILSQQPYNSKSDIWSLGCVFYDITGKKGSD 115
>27405
Length = 532
Score = 53.5 bits (127), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 48/192 (25%), Positives = 84/192 (43%), Gaps = 8/192 (4%)
Frame = -3
Query: 350 FGQAIKVTHRETGEVMVMKEL--IRFDEETQRTFLKEVKVMRCL-----EHPNVLKFIGV 402
FG+ +TG++ MK L R + T ++M L P ++
Sbjct: 527 FGEVYGCRKADTGKMYAMKCLDKKRIKMKGGETLALNERIMLSLVSTGEGSPFIVCMTYA 348
Query: 403 LYKDKRLNFITEYIKGGTLRGIIKSMDSQYPWSQRVSFAKDIASGMAYLHSMNIIHRDLN 462
++L FI + + GG L + S + + +A ++ G+ ++HS +++RDL
Sbjct: 347 FQTPEKLCFILDLMNGGDLHYHL-SQHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLK 171
Query: 463 SHNCLVRENKNVVVADFGLARLMVDEKTQPEGLRSLKKPDRKKRYTVVGNPYWMAPE-MI 521
N L+ EN +V ++D GLA +KK + VG +MAPE ++
Sbjct: 170 PANILLDENGHVRISDLGLA----------------CDFSKKKPHASVGTHGYMAPEVLM 39
Query: 522 NGRSYDEKVDVF 533
G++YD D F
Sbjct: 38 KGQAYDSSADWF 3
>09680
Length = 878
Score = 53.1 bits (126), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 35/108 (32%), Positives = 55/108 (50%), Gaps = 9/108 (8%)
Frame = -2
Query: 24 VCASCGQRIYDGQYLQALNADWHADCFRCCD--CSASLS-HQYYEKDGQLFCKKDYWARY 80
CA C + I+ G + A+ +WH CF C D C L ++E++G+ +C++DY +
Sbjct: 541 TCAGCKEPIH-GTTISAMGNNWHEHCFVC-DGACKQPLKDSSFFEREGKAYCRQDYEDLF 368
Query: 81 GESCHGCSEQITKGLVMVAGELKYHPECFICLTCG------TFIGDGD 122
C C + IT+ + VA K+H +CF C C TF +GD
Sbjct: 367 AVRCAKCEKPITENAI-VAMNAKWHSDCFCCNRCDNPIKTKTFTIEGD 227
Score = 37.7 bits (86), Expect = 0.015, Method: Compositional matrix adjust.
Identities = 26/88 (29%), Positives = 40/88 (45%), Gaps = 1/88 (1%)
Frame = -2
Query: 25 CASCGQRIYDGQYLQALNADWHADCFRCCDCSASLSHQYYE-KDGQLFCKKDYWARYGES 83
C C + I + + AL ++H + F C DC + + + G+ C Y RY +
Sbjct: 715 CHKCNEAI-TSRVVFALGKNYHPEHFLCRDCDKQIKDDIFNIQQGEPVCNACYLERYTST 539
Query: 84 CHGCSEQITKGLVMVAGELKYHPECFIC 111
C GC E I G + A +H CF+C
Sbjct: 538 CAGCKEPI-HGTTISAMGNNWHEHCFVC 458
Score = 35.8 bits (81), Expect = 0.057, Method: Compositional matrix adjust.
Identities = 22/67 (32%), Positives = 33/67 (49%)
Frame = -2
Query: 78 ARYGESCHGCSEQITKGLVMVAGELKYHPECFICLTCGTFIGDGDTYTLVEHSKLYCGHC 137
A+ CH C+E IT +V G+ YHPE F+C C I D D + ++ + C C
Sbjct: 733 AKQQYQCHKCNEAITSRVVFALGK-NYHPEHFLCRDCDKQIKD-DIFN-IQQGEPVCNAC 563
Query: 138 YYQTVVT 144
Y + +
Sbjct: 562 YLERYTS 542
>21433
Length = 590
Score = 53.1 bits (126), Expect(2) = 3e-07, Method: Compositional matrix adjust.
Identities = 29/104 (27%), Positives = 53/104 (50%)
Frame = +2
Query: 440 FAKDIASGMAYLHSMNIIHRDLNSHNCLVRENKNVVVADFGLARLMVDEKTQPEGLRSLK 499
+ ++S + Y H +IHRD+ N L+ ++ +ADFG S+
Sbjct: 182 YIYQLSSALEYCHYRKVIHRDIKPENLLLGLKGDLKIADFGW---------------SVH 316
Query: 500 KPDRKKRYTVVGNPYWMAPEMINGRSYDEKVDVFSFGIVLCEII 543
P +R T+ G ++ PEM+ G+++DE VD++S G++ E +
Sbjct: 317 APS-SRRTTMCGTLDYLPPEMVEGKTHDENVDLWSLGVLCYEFL 445
Score = 19.6 bits (39), Expect(2) = 3e-07, Method: Compositional matrix adjust.
Identities = 6/12 (50%), Positives = 9/12 (75%)
Frame = +3
Query: 583 TVRCCDLDPEKR 594
++ CC +DP KR
Sbjct: 555 SLSCCAIDPRKR 590
>22005
Length = 873
Score = 52.4 bits (124), Expect = 6e-07, Method: Compositional matrix adjust.
Identities = 58/254 (22%), Positives = 101/254 (39%), Gaps = 55/254 (21%)
Frame = +1
Query: 345 LGKGCFGQAIKVTH----RETGEVM------VMKELIRFD--EETQRTFLKEVKVMRCLE 392
+G+G FG+ K+ GE++ ++ ++++ D E+ Q F +E +M +
Sbjct: 7 IGQGAFGRVSKLKFLGLASLVGELIPEKRP*LL*KMLKEDASEDLQSDFEREASLMADFD 186
Query: 393 HPNVLKFIGVLYKDKRLNFITEYIKGGTLRGIIK-------------------------- 426
HPN++K +GV K + + E++ G L ++
Sbjct: 187 HPNIVKLLGVCAIGKPMCLLFEFMSKGDLNDFLRLCSPENYNLPVSRSQNLVVDLEDGLR 366
Query: 427 --------SMDSQ---------YPWSQRVSFAKDIASGMAYLHSMNIIHRDLNSHNCLVR 469
D+Q ++ ++ I++GMAYL + +HRDL + +
Sbjct: 367 VEVEAEECEKDTQSEDRDCSGMLXTKDQLYISQQISAGMAYLAQKDYVHRDL-ATRTVXS 543
Query: 470 ENKNVVVADFGLARLMVDEKTQPEGLRSLKKPDRKKRYTVVGNPYWMAPEMINGRSYDEK 529
++DFGLAR V G P R WM E I + +
Sbjct: 544 RTT*S*ISDFGLAR-SVHSVDYYRGSEQDAIPIR-----------WMPLEAILYSKFSTQ 687
Query: 530 VDVFSFGIVLCEII 543
DV+SFG+VL EI+
Sbjct: 688 SDVWSFGVVLWEIL 729
>31885
Length = 529
Score = 52.4 bits (124), Expect = 6e-07, Method: Compositional matrix adjust.
Identities = 50/176 (28%), Positives = 76/176 (43%), Gaps = 15/176 (8%)
Frame = -2
Query: 385 VKVMRCLEHPNVLKFIGVLYKDKRLNFITEYIKGGTLRGIIKSMDSQYPWSQRVSFAKD- 443
V ++ L+HP ++ ++ L + + GG LR Y Q VSF +D
Sbjct: 519 VDMLTRLDHPFLVNLWYAFQDEEDLFMVVDLFLGGDLR---------YHMQQEVSFREDC 367
Query: 444 -------IASGMAYLHSMNIIHRDLNSHNCLVRENKNVVVADFGLARLMVDEK--TQPEG 494
+A + YL S I+HRD+ N L+ E + V DF +A + D++ T G
Sbjct: 366 VKFYLCQLALVLDYLRSQKIVHRDIKPDNILLDEQGHCHVTDFNIATQLEDDELATSTSG 187
Query: 495 LRSLKKPDRKKRYTVVGNPYWMAPEM----ING-RSYDEKVDVFSFGIVLCEIIGR 545
R PY MAPE+ IN R Y VD +S G+ L E++ +
Sbjct: 186 TR----------------PY-MAPEVYGVAINERRGYGFPVDWWSLGVSLFELLKK 70
>01392
Length = 1806
Score = 49.7 bits (117), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 37/109 (33%), Positives = 53/109 (48%), Gaps = 11/109 (10%)
Frame = -1
Query: 442 KDIASGMAYLHSMNIIHRDLNSHNCLVRENKNVV---VADFGLARLMV---DEKTQPEGL 495
+ IA + +LHS I HRDL N L +VV + DF LA + D PE L
Sbjct: 1770 RHIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGISCDGDGTKTPELL 1591
Query: 496 RSLKKPDRKKRYTVVGNPYWMAPEMINGR-----SYDEKVDVFSFGIVL 539
T VG+ +MAPE+++ SYD++ D++S GI+L
Sbjct: 1590 ------------TPVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIIL 1480
>04138
Length = 800
Score = 47.0 bits (110), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 30/100 (30%), Positives = 49/100 (49%), Gaps = 2/100 (2%)
Frame = +1
Query: 448 MAYLHSMNIIHRDLNSHNCLVRENKNVVVADFGLARLMVDEKTQPEGLRSLKKPDRKKRY 507
+ Y+H I+HRD+ + N L+ + + +ADFGLAR QP RY
Sbjct: 52 LYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPN------------RY 195
Query: 508 T-VVGNPYWMAPEMING-RSYDEKVDVFSFGIVLCEIIGR 545
T V ++ PE++ G R+Y +D + G ++ E+ R
Sbjct: 196 TNRVVTLWYRPPELLLGDRNYSTAIDQWGAGCIMAEMWTR 315
>17806
Length = 433
Score = 46.2 bits (108), Expect = 4e-05, Method: Compositional matrix adjust.
Identities = 40/140 (28%), Positives = 71/140 (50%), Gaps = 10/140 (7%)
Frame = +1
Query: 323 SLRVVCRPHRIFRPSDLIHGEVLGKGCFGQAIKV-THRETGEVMVMKELIRF--DEET-- 377
SL+++ H F S +++ + LG G FG+ I+ R T V K +++ D+ T
Sbjct: 10 SLKMIA-GHHPFPRSQIVYLKELGTGWFGKVIESDAERITTGVSRSKVVVKMLKDDATKD 186
Query: 378 -QRTFLKEVKVMRCLEHPNVLKFIGVLYKDKRLNFITEYIKGGTLRGIIKSMDSQYPW-- 434
Q F +EV R L+HPN+++ +G + + + E G L+ +++ Q
Sbjct: 187 EQLLFFEEVAPFRELDHPNIVRLLGQCTEMNPMLMLMECAALGNLKQYLRNHRHQQAMLI 366
Query: 435 --SQRVSFAKDIASGMAYLH 452
++ + FA DI+SG+A LH
Sbjct: 367 QKNRLLKFAMDISSGLACLH 426
>11185
Length = 473
Score = 45.8 bits (107), Expect = 6e-05, Method: Composition-based stats.
Identities = 33/127 (25%), Positives = 55/127 (43%), Gaps = 16/127 (12%)
Frame = +1
Query: 440 FAKDIASGMAYLHSMNIIHRDLNSHNCLVRENKNVVVADFGLARLMVDEKTQPEGLRSL- 498
F + +G+ Y+HS+ I+ DL L+ + + ADFGL+ K + E L L
Sbjct: 16 FGIHLVTGLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLS------KVEGENLEELF 177
Query: 499 -------------KKPDRKKRYTVVGNPYWMAPEMINGRSYDEKVDVFSFGIVLCEII-- 543
+ K+ G+P +MAPE+ G D+++ G V E+
Sbjct: 178 FKFAEAGDQWNIQSAEEMMKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSG 357
Query: 544 GRVNADP 550
R++A P
Sbjct: 358 SRLSAKP 378
>17637
Length = 447
Score = 45.1 bits (105), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 27/92 (29%), Positives = 45/92 (48%), Gaps = 5/92 (5%)
Frame = +1
Query: 515 WMAPEMINGRSYDEKVDVFSFGIVLCEI--IGRV---NADPDYLPRTMDFGLNVRGFLDR 569
W++ E + Y+E DV+SFG+++ E+ +G++ DP + + G +
Sbjct: 115 WLSLEALQKSHYNEGSDVWSFGVLMWEMCTLGKLPYAEIDPYEMEHYLKDGYRLAQ---- 282
Query: 570 YCPPNCPPSFFPITVRCCDLDPEKRPSFVKLE 601
P NCP F I C P +RPSF +L+
Sbjct: 283 --PFNCPDELFTIMAYCWASMPAERPSFSQLQ 372
>20559
Length = 430
Score = 44.3 bits (103), Expect = 1e-04, Method: Composition-based stats.
Identities = 20/73 (27%), Positives = 46/73 (63%), Gaps = 3/73 (4%)
Frame = -2
Query: 343 EVLGKGCFGQAIKVTHRETGEVMVMKELIRFDEETQ---RTFLKEVKVMRCLEHPNVLKF 399
E +G+G +G K +RET E++ +K +R D++ + + L+E+ +++ L+H N+++
Sbjct: 357 EKIGEGTYGTVFKAKNRETHEIVALKR-VRLDDDDEGVPSSALREICLLKELKHRNIVRL 181
Query: 400 IGVLYKDKRLNFI 412
VL+ +++L +
Sbjct: 180 HDVLHSERKLTLV 142
>03508
Length = 1463
Score = 43.9 bits (102), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 32/109 (29%), Positives = 56/109 (51%), Gaps = 3/109 (2%)
Frame = +1
Query: 440 FAKDIASGMAYLHSMNIIHRDLNSHNCLV-RENKNVVVADFGLARLMVDEKTQPEGLRSL 498
+ ++ + + HSM I+HRD+ HN ++ ENK + + D+GLA E P G+
Sbjct: 886 YLYELMKALDFCHSMGIMHRDVKPHNVMIDHENKKLRLIDWGLA-----EFYHP-GM--- 1038
Query: 499 KKPDRKKRYTV-VGNPYWMAPE-MINGRSYDEKVDVFSFGIVLCEIIGR 545
Y V V + Y+ PE +++ + YD +D++S G + +I R
Sbjct: 1039-------EYNVRVASRYFKGPELLLDYQMYDYSLDMWSLGCMFASMIFR 1164
>14307
Length = 816
Score = 43.5 bits (101), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 32/118 (27%), Positives = 51/118 (43%), Gaps = 2/118 (1%)
Frame = +2
Query: 23 PVCASCGQRIYDGQYLQALNADWHADCFRCCDCSASL-SHQYYEKDGQLFCKKDYWARYG 81
P C C + I+ G+Y +A+ +H D C C L S +Y +D C Y A +
Sbjct: 368 PRCPGCDELIFSGEYTKAMEECYHKDHLACWQCDKQLVSCRYIMRDDHPHCVPCYQALFA 547
Query: 82 ESCHGCSEQITKGLVMVAGELK-YHPECFICLTCGTFIGDGDTYTLVEHSKLYCGHCY 138
C C + I ++ + K +H CF C C + D ++ K++C CY
Sbjct: 548 NKCEDCDKPIGPDYKDLSYKDKHWHEFCFKCTMCDKSLVDQP--FAPKNEKIFCSECY 715
Score = 36.6 bits (83), Expect = 0.030, Method: Compositional matrix adjust.
Identities = 24/71 (33%), Positives = 29/71 (40%), Gaps = 1/71 (1%)
Frame = +2
Query: 45 WHADCFRCCDCSASLSHQYY-EKDGQLFCKKDYWARYGESCHGCSEQITKGLVMVAGELK 103
WH CF C C L Y + D L+C++ Y C GC E I G A E
Sbjct: 254 WHPACFVCSTCEELLVDLVYCQHDKHLYCQRHYAELIRPRCPGCDELIFSGEYTKAMEEC 433
Query: 104 YHPECFICLTC 114
YH + C C
Sbjct: 434 YHKDHLACWQC 466
Score = 35.4 bits (80), Expect = 0.069, Method: Compositional matrix adjust.
Identities = 23/77 (29%), Positives = 35/77 (45%), Gaps = 2/77 (2%)
Frame = +2
Query: 34 DGQYLQALNADWHADCFRCCDCSASLSHQ-YYEKDGQLFCKKDYWARYGESCHGCSEQIT 92
D + L + WH CF+C C SL Q + K+ ++FC + Y + C GC
Sbjct: 584 DYKDLSYKDKHWHEFCFKCTMCDKSLVDQPFAPKNEKIFCSECYDNSFAARCDGCGNPFK 763
Query: 93 KGLVMVAGELK-YHPEC 108
G+ + K +H EC
Sbjct: 764 GGMKKFEYKGKQWHDEC 814
Score = 31.6 bits (70), Expect = 1.0, Method: Compositional matrix adjust.
Identities = 23/69 (33%), Positives = 35/69 (50%), Gaps = 6/69 (8%)
Frame = +2
Query: 83 SCHGCSEQITK-GLVMVAGELK----YHPECFICLTCGTFIGDGDTYTLVEHSK-LYCGH 136
+CH C +I K LV+ A ++ +HP CF+C TC + D +H K LYC
Sbjct: 176 TCHCCKGEIDKLELVVTAPKVGEGTVWHPACFVCSTCEELLVD---LVYCQHDKHLYCQR 346
Query: 137 CYYQTVVTP 145
+Y ++ P
Sbjct: 347 -HYAELIRP 370
>16708
Length = 1397
Score = 42.7 bits (99), Expect = 5e-04, Method: Compositional matrix adjust.
Identities = 49/215 (22%), Positives = 82/215 (38%), Gaps = 11/215 (5%)
Frame = -1
Query: 343 EVLGKGCFGQAIKVTHRETGEVMVMKELIRFDEETQRTFLKEVKVMRCLEHPNVL-KFIG 401
+VLGKG FG+ + T E +K I L EV+ + +E L + G
Sbjct: 1385 QVLGKGVFGKVYEARLLSTHEKAALKTSILCHHS-----LDEVEALGRIEGGFYLAQMFG 1221
Query: 402 VLYK---DKRLNFITEYIKGGTLRGII---KSMDSQYPWSQRVS---FAKDIASGMAYLH 452
++N + + + G L + K+ + WS A + ++H
Sbjct: 1220 AWVTCLPFPKMNILLHFYEMGPLCNVYAHYKNKEMPIRWSNPAMVCCIAGQXVCALEHIH 1041
Query: 453 SMNIIHRDLNSHNCLVRENKNVVVADFGLARLMVDEKTQPEGLRSLKKPDRKKRYTVVGN 512
+ ++H D+ + N LV + N + D+G+A+L K P + KR
Sbjct: 1040 ELGVVHMDVKADNVLVDAHGNCKLTDYGIAQLY---KVYPAPTETHSSGCTNKRTFYTRP 870
Query: 513 PYWMAP-EMINGRSYDEKVDVFSFGIVLCEIIGRV 546
P M P E + D F G +L + G V
Sbjct: 869 PATMTPSERFSEEGDGIGTDYFRLGQMLWTLTGAV 765
>05726
Length = 733
Score = 42.4 bits (98), Expect = 6e-04, Method: Compositional matrix adjust.
Identities = 31/109 (28%), Positives = 49/109 (44%), Gaps = 5/109 (4%)
Frame = +1
Query: 18 EGSELPVCASCGQRIYDGQYLQALNADWHADCFRCCDCSASLS-HQYYEKDGQLFCKKDY 76
E + C C Q I G + N WH +CF C C L+ ++ KD Q +C +
Sbjct: 52 ENNYAQRCFKCSQVINKGG-ISYKNTPWHRECFTCTHCDKMLAGEKFTSKDDQPYCGDCF 228
Query: 77 WARYGESCHGCSEQIT--KGLVMVAGELK-YHPECFICLTC-GTFIGDG 121
+ + C C + IT G ++ E + +H +CF C C + +G G
Sbjct: 229 GDLFAKKCCRCQKAITGIGGTKFISFEERHWHSDCFTCFKCQASMVGRG 375
>18996
Length = 491
Score = 42.0 bits (97), Expect = 8e-04, Method: Compositional matrix adjust.
Identities = 42/152 (27%), Positives = 65/152 (42%), Gaps = 8/152 (5%)
Frame = +2
Query: 457 IHRDLNSHNCLVRENKNVVVADFGLARLMVDEKTQPEGLRSLKKPDRKKRYTVVGNPYWM 516
IHRDL + N LV + V ++DFGLA+ + G+ P + W
Sbjct: 2 IHRDLAARNILV-DRSCVKISDFGLAQF-ANADGYYYGISQRDIPIK-----------WY 142
Query: 517 APEMINGRSYDEKVDVFSFGIVLCEIIGRVNADPDYLPRTMDFGLNVRGFLDRY------ 570
+PE I + DV+S+G+ L E+ R P+ LP L FL+R
Sbjct: 143 SPEAIETCKFSSYSDVWSYGVTLFEMFSRGEI-PNLLP---GHDLTQEEFLNRLRKGERL 310
Query: 571 -CPPNCPPSFFPITVRCCDLD-PEKRPSFVKL 600
P C + +R C + P+ RP+F ++
Sbjct: 311 PKPELCSDFVYSELMRPCWHEMPKSRPTFHQI 406
>32359
Length = 928
Score = 40.8 bits (94), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 26/90 (28%), Positives = 50/90 (55%), Gaps = 8/90 (8%)
Frame = -1
Query: 335 RPSDLIH--GEVLGKGCFGQAIKVTHRETGEVMVMKELIRFDEETQRTFLKEVKVMRCLE 392
RP ++ + +V+G G FG + +T E++ +K+++ + +R +E+++MR LE
Sbjct: 442 RPQEVSYTDAKVIGNGSFGVVYQAKLVDTSELVAIKKVL----QDKRFKNRELQIMRKLE 275
Query: 393 HPNVLKFIGVLY-----KDK-RLNFITEYI 416
H N++K Y KD+ LN + EY+
Sbjct: 274 HQNIVKLKFFFYSSGEKKDEVFLNLVLEYV 185
>07437
Length = 951
Score = 38.5 bits (88), Expect = 0.009, Method: Compositional matrix adjust.
Identities = 28/94 (29%), Positives = 43/94 (45%), Gaps = 1/94 (1%)
Frame = +3
Query: 22 LPVCASCGQRIYDGQYLQALNADWHADCFRCCDCSA-SLSHQYYEKDGQLFCKKDYWARY 80
+P+C +C +R + + + AL WH + F C C L ++YEK G +C+ Y +
Sbjct: 327 IPICGAC-RRPIEERVVHALGKAWHVEHFVCAKCEKPFLGTRHYEKKGLAYCEIHYHQLF 503
Query: 81 GESCHGCSEQITKGLVMVAGELKYHPECFICLTC 114
G C C+ I G V A + F C C
Sbjct: 504 GNICFVCN-NIINGDVFSAFNKAWCVHHFACSIC 602
Score = 36.2 bits (82), Expect = 0.038, Method: Compositional matrix adjust.
Identities = 31/108 (28%), Positives = 50/108 (46%), Gaps = 7/108 (6%)
Frame = +3
Query: 38 LQALNADWHADCFRCCDCSASLSHQYYEKD-GQLFCKKDYWARYGES-----CHGCSEQI 91
++A+N+ WH CF C C ++ + K+ G+ C++ CH C + I
Sbjct: 3 IKAMNSAWHPQCFLCQLCGTCMADSGFVKNAGRALCRECNAKEKARGTGKYVCHKCHDVI 182
Query: 92 -TKGLVMVAGELKYHPECFICLTCGTFIGDGDTYTLVEHSKLYCGHCY 138
G + GE YHP F C +CG + +T + S+LYC C+
Sbjct: 183 EMNGHIKFRGEA-YHPYHFNCHSCGV---ELNTEAREKDSELYCLRCH 314
Score = 30.0 bits (66), Expect = 3.4, Method: Compositional matrix adjust.
Identities = 30/122 (24%), Positives = 51/122 (41%), Gaps = 7/122 (5%)
Frame = +3
Query: 19 GSELPVCASCGQRIYDGQYLQALNADWHADCFRCCDCSASLSHQYYEKDGQLFCKKDYWA 78
G+ VC C I +++ +H F C C L+ + EKD +L+C + +
Sbjct: 141 GTGKYVCHKCHDVIEMNGHIKFRGEAYHPYHFNCHSCGVELNTEAREKDSELYCLRCHDK 320
Query: 79 RYGESCHGCSEQITKGLVMVAGELKYHPECFICLTCGT-FIG------DGDTYTLVEHSK 131
C C I + +V G+ +H E F+C C F+G G Y + + +
Sbjct: 321 MGIPICGACRRPIEERVVHALGKA-WHVEHFVCAKCEKPFLGTRHYEKKGLAYCEIHYHQ 497
Query: 132 LY 133
L+
Sbjct: 498 LF 503
>13305
Length = 549
Score = 38.5 bits (88), Expect = 0.009, Method: Composition-based stats.
Identities = 25/87 (28%), Positives = 42/87 (48%), Gaps = 1/87 (1%)
Frame = +2
Query: 515 WMAPEMINGRSYDEKVDVFSFGIVLCEIIGRVNADPDYLPRTMDFGLNVRGF-LDRYCPP 573
WMA E + +Y + DV+SFG+VL EI F G+ L R P
Sbjct: 23 WMAVESLFNNTYTTQSDVWSFGVVLWEIFTLGGTPYSSTDTQQLFAFLKDGYRLKR--PK 196
Query: 574 NCPPSFFPITVRCCDLDPEKRPSFVKL 600
C + + + ++C + + ++RP+F +L
Sbjct: 197 LCDQNTYAMMLQCWNENAQRRPTFPEL 277
>37602
Length = 804
Score = 37.0 bits (84), Expect = 0.023, Method: Compositional matrix adjust.
Identities = 25/90 (27%), Positives = 46/90 (51%), Gaps = 5/90 (5%)
Frame = -1
Query: 395 NVLKFIGVL---YKDKRLNFITEYIKGGTLRGIIKSMDSQYPWSQ-RVSFA-KDIASGMA 449
N+ F+G + ++L EY GG+++ I P ++ +++F ++ G+
Sbjct: 345 NIQTFVGYFDSYLRREKLWIAMEYCGGGSMQDIYHVTG---PLTEPQIAFVCRETLKGLH 175
Query: 450 YLHSMNIIHRDLNSHNCLVRENKNVVVADF 479
YLH +HRD+ N L+ E +V +ADF
Sbjct: 174 YLHRRGKMHRDIKGANILLTEEGDVKLADF 85
>30169
Length = 426
Score = 37.0 bits (84), Expect = 0.025, Method: Composition-based stats.
Identities = 17/64 (26%), Positives = 29/64 (45%), Gaps = 1/64 (1%)
Frame = -1
Query: 24 VCASCGQRIYDGQYLQALNADWHADCFRCCDCSASL-SHQYYEKDGQLFCKKDYWARYGE 82
+CA CG+ +Y + + + +H CF+C C L S + ++CK Y +G
Sbjct: 408 MCAVCGKAVYFAERVAGMGKVYHKACFKCTSCRKILDSTLLTQHQDNIYCKACYGKNFGP 229
Query: 83 SCHG 86
G
Sbjct: 228 KGFG 217
Score = 29.3 bits (64), Expect = 4.6, Method: Composition-based stats.
Identities = 17/43 (39%), Positives = 22/43 (51%), Gaps = 2/43 (4%)
Frame = -1
Query: 98 VAGELK-YHPECFICLTCGTFIGDGDTYTLVEHS-KLYCGHCY 138
VAG K YH CF C +C + D+ L +H +YC CY
Sbjct: 366 VAGMGKVYHKACFKCTSCRKIL---DSTLLTQHQDNIYCKACY 247
>00394
Length = 548
Score = 36.6 bits (83), Expect = 0.030, Method: Composition-based stats.
Identities = 22/89 (24%), Positives = 45/89 (50%), Gaps = 7/89 (7%)
Frame = -2
Query: 345 LGKGCFGQAIKVTHRETGEVMVMKEL--IRFDEETQRTFLKEVKVMRCLEHPNVLKFIGV 402
+G+G F K E G + EL ++++ ++ F +E ++++ L+HPN+++F
Sbjct: 274 IGRGSFKTVYKGLDTELGVAVAWCELQDKKWNKAERQRFKEEAEMLKELQHPNIVRFFDY 95
Query: 403 LYKDKRLN-----FITEYIKGGTLRGIIK 426
+ N +TE + GTL+ +K
Sbjct: 94 WEEHNHRNRKVIILVTELMTSGTLKTYLK 8
>17516
Length = 453
Score = 36.2 bits (82), Expect = 0.045, Method: Composition-based stats.
Identities = 16/36 (44%), Positives = 23/36 (63%), Gaps = 1/36 (2%)
Frame = -3
Query: 508 TVVGNPYWMAPE-MINGRSYDEKVDVFSFGIVLCEI 542
T+ G P +MAPE ++ YD K DV+S I+L E+
Sbjct: 442 TLAGTPVYMAPEVLLQKGQYDMKADVYSLAIILWEL 335
>31789
Length = 676
Score = 35.0 bits (79), Expect = 0.096, Method: Compositional matrix adjust.
Identities = 35/156 (22%), Positives = 65/156 (41%), Gaps = 9/156 (5%)
Frame = +2
Query: 280 PSGEAGSSARQKPVLRSCSIDR--XXXXXXXXXXXXQRKDLGRSESLRVVCRPHRIFRPS 337
P G+ GS+ R+ + S D Q + + E V P F
Sbjct: 155 PPGQFGSTERKTITIDSALSDTGIKLQLEGEIKDIQQAQKVQEIEEKAVASSPDNRFLKF 334
Query: 338 DLIHGEVLGKGCFGQAIKVTHRETGEVMVMKEL--IRFDEETQRTFLKEVKVMRCLEHPN 395
D+ +G+G F K E G + EL ++++ ++ F +E ++++ L+HPN
Sbjct: 335 DV----EIGRGSFKTVYKGLDTELGVAVAWCELQDKKWNKTERQRFKEEAEMLKELQHPN 502
Query: 396 VLKFIGVLYKDKRLN-----FITEYIKGGTLRGIIK 426
+++F + N +TE + GTL+ +K
Sbjct: 503 IVRFFDYWEEHNHRNRKVIILVTELMTSGTLKTYLK 610
>31489
Length = 329
Score = 34.3 bits (77), Expect = 0.17, Method: Composition-based stats.
Identities = 24/88 (27%), Positives = 39/88 (44%), Gaps = 5/88 (5%)
Frame = +3
Query: 385 VKVMRCLEHPNVLKFIGVL-----YKDKRLNFITEYIKGGTLRGIIKSMDSQYPWSQRVS 439
+K+++ +H N++ +L Y D + + + L II S D
Sbjct: 3 IKILKHFKHDNIISIREILKPKDSYHDFKDIHVVFDLMESDLHRIIYS-DQPLTEEHIRY 179
Query: 440 FAKDIASGMAYLHSMNIIHRDLNSHNCL 467
F I G+ Y+HS N++HRDL N L
Sbjct: 180 FLYQILRGLKYIHSANVVHRDLKPSNLL 263
>02638
Length = 1490
Score = 33.9 bits (76), Expect = 0.20, Method: Compositional matrix adjust.
Identities = 26/93 (27%), Positives = 44/93 (47%), Gaps = 5/93 (5%)
Frame = +1
Query: 509 VVGNPYWMAPEMINGRSYDEKVDVFSFGIVLCEIIG-RVNADPDYLPRTMDFGLNVRGFL 567
++G +MAPE++ G SY DV+S G V+ E+ R + + + + +
Sbjct: 16 LLGTIAFMAPEVLRGESYGRACDVWSVGCVMIEMCTCRPPWNSHDISNHLALIFKIASSV 195
Query: 568 DRYCPPNCPPSFFP----ITVRCCDLDPEKRPS 596
D PP P + P + +RC + D + RPS
Sbjct: 196 D---PPPIPENMSPPVRDLMLRCLEQDSDFRPS 285
>18663
Length = 600
Score = 33.1 bits (74), Expect = 0.32, Method: Compositional matrix adjust.
Identities = 13/37 (35%), Positives = 23/37 (62%)
Frame = +2
Query: 508 TVVGNPYWMAPEMINGRSYDEKVDVFSFGIVLCEIIG 544
T G P ++APE++ G Y VD ++ G++L E++
Sbjct: 5 TFCGTPNYIAPEILRGEDYGFSVDWWALGVLLYEMLA 115
>17982
Length = 477
Score = 33.1 bits (74), Expect = 0.36, Method: Composition-based stats.
Identities = 22/87 (25%), Positives = 41/87 (47%), Gaps = 9/87 (10%)
Frame = -1
Query: 344 VLGKGCFGQAIKVTHRETGEVMVMKELIRFDEETQRTFLKEVKVMRCLE-HPNVLKFI-- 400
++ +G F +G+ +K L+ DEE + + E+K ++ L HP++++FI
Sbjct: 264 LIAEGGFAFVFVAQDVNSGKDYALKRLLANDEENSKAIMDEIKYLKKLSGHPHIIQFITA 85
Query: 401 GVLYKDK------RLNFITEYIKGGTL 421
+ KD+ +TE GG L
Sbjct: 84 ASIGKDQSDHGQSEFLLLTELCSGGQL 4
>38046
Length = 446
Score = 33.1 bits (74), Expect = 0.39, Method: Composition-based stats.
Identities = 15/31 (48%), Positives = 17/31 (54%)
Frame = -1
Query: 444 IASGMAYLHSMNIIHRDLNSHNCLVRENKNV 474
IA MAY+ N IHR+L N LV N V
Sbjct: 98 IADAMAYMEKENFIHRNLGDRNILVGPNNRV 6
>08228
Length = 746
Score = 32.3 bits (72), Expect = 0.65, Method: Compositional matrix adjust.
Identities = 19/53 (35%), Positives = 27/53 (50%), Gaps = 7/53 (13%)
Frame = +3
Query: 579 FFPI-TVRCCDLDPEKR------PSFVKLEHWLETLRMHLAGHLPLGPQLEQL 624
+FPI T + D E++ PSF K++H L T+ H HLP QL +
Sbjct: 60 YFPI*TTKTIFSDFERKSFVIFKPSFYKIKHKLFTIPRHTYSHLPTATQLNSI 218
>26052
Length = 562
Score = 32.0 bits (71), Expect = 0.73, Method: Composition-based stats.
Identities = 11/35 (31%), Positives = 22/35 (62%)
Frame = -1
Query: 336 PSDLIHGEVLGKGCFGQAIKVTHRETGEVMVMKEL 370
P + ++LG G FG+ + + H++TGE + +K +
Sbjct: 394 PXQYLFXKLLGVGSFGKVMALQHKDTGETLAVKNI 290
>04349
Length = 1161
Score = 32.0 bits (71), Expect = 0.74, Method: Compositional matrix adjust.
Identities = 14/57 (24%), Positives = 27/57 (47%), Gaps = 1/57 (1%)
Frame = +3
Query: 21 ELPVCASCGQRIYDGQYLQALNADWHADCFRCCDCSASLSHQYYEKDGQ-LFCKKDY 76
+L C +C + +Y + ++ +H CFRC C L+ + + + +FC Y
Sbjct: 219 QLEKCGACHKTVYAMEKIEIEKNAYHKSCFRCSHCHCVLTPKTFAINKNVMFCTNHY 389
>01106
Length = 878
Score = 32.0 bits (71), Expect = 0.87, Method: Compositional matrix adjust.
Identities = 27/123 (21%), Positives = 51/123 (41%), Gaps = 15/123 (12%)
Frame = +3
Query: 361 TGEVMVMKELIRFDEETQRTFLKEVKVMRCLEHPNV--------------LKFIGVLYKD 406
T + V ++++ + T L EVK+++C+ +V K GV
Sbjct: 387 TCKRFVALKVVKSAQHYTETALDEVKLLKCVRESDVADPARAKCVQLLDDFKISGV--NG 560
Query: 407 KRLNFITEYIKGGTLRGIIKSMDSQYPWSQRVSFAKDIASGMAYLHSM-NIIHRDLNSHN 465
+ + E + L+ II+S P + + G++Y+H+ IIH D+ N
Sbjct: 561 THVAMVFEVLGYNLLKLIIRSNYQGIPIHNVKLIIRQVLEGLSYMHAKCRIIHTDIKPEN 740
Query: 466 CLV 468
L+
Sbjct: 741 ILI 749
>15741
Length = 402
Score = 31.6 bits (70), Expect = 1.0, Method: Composition-based stats.
Identities = 13/29 (44%), Positives = 20/29 (68%)
Frame = -3
Query: 439 SFAKDIASGMAYLHSMNIIHRDLNSHNCL 467
SFA +A GMA++ + I+HRD+ + N L
Sbjct: 88 SFALHVARGMAHVANNKIVHRDVAARNVL 2
>38751
Length = 329
Score = 31.6 bits (70), Expect = 1.2, Method: Composition-based stats.
Identities = 18/74 (24%), Positives = 39/74 (52%)
Frame = +3
Query: 192 GTEHSHTVRVQGVDPGCMSPDVKNSIHVGDRILEINGTPIRNVPLDEIDLLIQETSRLLQ 251
G E+ + V ++ GC + + +++GDRIL++NGT ++ E +++ ++
Sbjct: 18 GKEYGTPIVVYVIEEGCQAE--QQGLNIGDRILDVNGTDFTHLTHAEAVTIMRNAWNVI- 188
Query: 252 LTLEHDPHDTLGHG 265
+T++ P G G
Sbjct: 189 MTVQPCPESDSGQG 230
>37063
Length = 455
Score = 31.2 bits (69), Expect = 1.3, Method: Composition-based stats.
Identities = 15/37 (40%), Positives = 25/37 (67%), Gaps = 5/37 (13%)
Frame = -2
Query: 508 TVVGNPYWMAPEMINGR-----SYDEKVDVFSFGIVL 539
T VG+ +MAPE+++ SYD++ D++S GI+L
Sbjct: 331 TPVGSAEYMAPEVVDAWVGESFSYDKRCDMWSLGIIL 221
>21800
Length = 855
Score = 31.2 bits (69), Expect = 1.3, Method: Compositional matrix adjust.
Identities = 28/109 (25%), Positives = 50/109 (45%), Gaps = 13/109 (11%)
Frame = +2
Query: 380 TFLKEVKVMRCLEH-----PNVLKFIGVL--YKDKRLN-----FITEYIKGGTLRGIIKS 427
T L E+K+++C+ + P K + +L +K +N + E + L+ II+S
Sbjct: 431 TALDEIKLLKCVRNSDETDPAREKSVQLLDDFKISGVNGTHVCMVFEVLGYNLLKLIIRS 610
Query: 428 MDSQYPWSQRVSFAKDIASGMAYLHSM-NIIHRDLNSHNCLVRENKNVV 475
P + + G+ YLH+ NIIH D+ N L+ + N +
Sbjct: 611 NYQGIPVHNVKLIIRQVLEGLNYLHAKCNIIHTDIKPENILICVDDNYI 757
>03831
Length = 1143
Score = 31.2 bits (69), Expect = 1.3, Method: Compositional matrix adjust.
Identities = 22/59 (37%), Positives = 31/59 (52%), Gaps = 3/59 (5%)
Frame = +3
Query: 204 VDPGCMSPDVKNSIHVGDRILEINGTPIRNVPLDEIDLLIQ---ETSRLLQLTLEHDPH 259
VD G SP + GDRI+E+NGT I N ++ I+ + +RLL + E D H
Sbjct: 225 VDEG--SPAEAAGLKAGDRIVEVNGTNIGNENHQQVVGRIKAGGDETRLLVVDQETDQH 395
>03731
Length = 728
Score = 31.2 bits (69), Expect = 1.5, Method: Compositional matrix adjust.
Identities = 11/44 (25%), Positives = 22/44 (50%)
Frame = +2
Query: 21 ELPVCASCGQRIYDGQYLQALNADWHADCFRCCDCSASLSHQYY 64
+L C +C + +Y + ++ +H CFRC C L+ + +
Sbjct: 575 QLEKCGACHKTVYAMEKIEIEKNAYHKSCFRCSHCHCVLTPKTF 706
>05103
Length = 1504
Score = 30.8 bits (68), Expect = 1.6, Method: Compositional matrix adjust.
Identities = 17/61 (27%), Positives = 31/61 (50%), Gaps = 3/61 (4%)
Frame = +2
Query: 16 GEEGSELPV--CASCGQRIYDGQYLQALNADWHADCFRCCDCSASLSHQ-YYEKDGQLFC 72
GE+ + P C C + G ++A +H CF+C CS +L + ++ D +L+C
Sbjct: 611 GEQKQQQPSMRCGGC-DMLATGVIVKANGVPYHVACFKCESCSMNLKQKGFFVVDDKLYC 787
Query: 73 K 73
+
Sbjct: 788 E 790
Score = 30.8 bits (68), Expect = 1.7, Method: Compositional matrix adjust.
Identities = 16/51 (31%), Positives = 25/51 (49%)
Frame = +2
Query: 84 CHGCSEQITKGLVMVAGELKYHPECFICLTCGTFIGDGDTYTLVEHSKLYC 134
C GC + + G+++ A + YH CF C +C + + V KLYC
Sbjct: 644 CGGC-DMLATGVIVKANGVPYHVACFKCESCSMNLKQKGFF--VVDDKLYC 787
>26009
Length = 886
Score = 30.8 bits (68), Expect = 1.8, Method: Compositional matrix adjust.
Identities = 10/30 (33%), Positives = 18/30 (60%)
Frame = +3
Query: 439 SFAKDIASGMAYLHSMNIIHRDLNSHNCLV 468
S K + S + ++HS ++HRD+ N L+
Sbjct: 723 SVMKQLVSALDFMHSKQLVHRDIKPENVLI 812
>32264
Length = 287
Score = 30.8 bits (68), Expect = 1.9, Method: Compositional matrix adjust.
Identities = 15/43 (34%), Positives = 23/43 (53%)
Frame = +1
Query: 573 PNCPPSFFPITVRCCDLDPEKRPSFVKLEHWLETLRMHLAGHL 615
P P S + + +RC + PEKRP F +L L+ + L H+
Sbjct: 31 PQTPDSVYKLMLRCWEYVPEKRPHFKELYTSLKDIVRKL*THI 159
>35055
Length = 641
Score = 30.4 bits (67), Expect = 2.1, Method: Composition-based stats.
Identities = 12/27 (44%), Positives = 18/27 (66%)
Frame = -2
Query: 450 YLHSMNIIHRDLNSHNCLVRENKNVVV 476
+LHS NI+ + LNS C R+N N+ +
Sbjct: 388 FLHSFNILQKTLNSKFCHHRKNTNLTL 308
>38560
Length = 479
Score = 30.4 bits (67), Expect = 2.4, Method: Composition-based stats.
Identities = 13/33 (39%), Positives = 22/33 (66%), Gaps = 1/33 (3%)
Frame = -3
Query: 508 TVVGNPYWMAPEMINGRSY-DEKVDVFSFGIVL 539
T G+P + APE+I+G Y + D++S G++L
Sbjct: 408 TCCGSPAYAAPELISGLEYLGSEADIWSMGVLL 310
>05111
Length = 1909
Score = 30.0 bits (66), Expect = 2.9, Method: Compositional matrix adjust.
Identities = 15/43 (34%), Positives = 22/43 (51%)
Frame = +2
Query: 41 LNADWHADCFRCCDCSASLSHQYYEKDGQLFCKKDYWARYGES 83
+N W CFR CD +LS+ Y+ K + C Y A + E+
Sbjct: 398 VNQRWLDFCFRKCDIVITLSYIYFGKVDLILCLLKYGAVHTEN 526
>18481
Length = 437
Score = 30.0 bits (66), Expect = 3.0, Method: Compositional matrix adjust.
Identities = 19/87 (21%), Positives = 38/87 (43%), Gaps = 3/87 (3%)
Frame = -1
Query: 406 DKRLNFITEYIKGGTLRGIIKSMDSQYPWSQRVSFAKDIASGMAYLHSMNIIHRDLNSHN 465
+K N + + G +L + ++ + + + S + ++H IHRDL N
Sbjct: 284 EKHFNALVMELLGPSLEELFVICKRRFTLKTILMVSDQLLSRLEFIHQKCFIHRDLKPDN 105
Query: 466 CLV---RENKNVVVADFGLARLMVDEK 489
L+ R + + DFGL++ D +
Sbjct: 104 FLMGLGRHCHRLYIIDFGLSKRYKDTQ 24
>25550
Length = 941
Score = 29.6 bits (65), Expect = 4.4, Method: Compositional matrix adjust.
Identities = 13/57 (22%), Positives = 29/57 (50%)
Frame = +3
Query: 572 PPNCPPSFFPITVRCCDLDPEKRPSFVKLEHWLETLRMHLAGHLPLGPQLEQLDRGF 628
P P + + ++C DP++RP+F ++ + LE + + + +LE+ D+
Sbjct: 105 PQGTPADVYILMLKCWQWDPKERPTFKEIHYLLENMFEKSSISEEVEKELEKNDKKL 275
>26762
Length = 399
Score = 28.9 bits (63), Expect = 6.0, Method: Compositional matrix adjust.
Identities = 12/33 (36%), Positives = 17/33 (51%)
Frame = +1
Query: 36 QYLQALNADWHADCFRCCDCSASLSHQYYEKDG 68
+++ WH DCF C C ASL + + DG
Sbjct: 112 RFISFEERHWHHDCFVCASCKASLVGRGFITDG 210
>07933
Length = 728
Score = 28.9 bits (63), Expect = 6.6, Method: Compositional matrix adjust.
Identities = 12/31 (38%), Positives = 17/31 (54%)
Frame = +3
Query: 572 PPNCPPSFFPITVRCCDLDPEKRPSFVKLEH 602
P CP + I ++C +P RP+F KLE
Sbjct: 3 PNYCPNLLYNIMMQCWSAEPSARPTFHKLEQ 95
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000376526 | hsapiens_gene_ensembl | Heat shock
cognate 71 kDa protein (Heat shock 70 kDa protein 8).
[Source:Uniprot/SWISSPROT;Acc:P11142]
(494 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
37715 152 2e-55
27378 199 2e-51
21024 189 2e-48
30255 178 3e-45
31218 95 6e-20
09881 91 1e-18
20979 84 1e-16
26390 68 1e-11
12271 63 3e-10
13684 55 5e-08
03996 51 1e-06
24750 50 1e-06
13300 45 4e-05
>37715
Length = 468
Score = 152 bits (384), Expect(2) = 2e-55, Method: Compositional matrix adjust.
Identities = 71/97 (73%), Positives = 84/97 (86%)
Frame = -2
Query: 94 VVNDAGRPKVQVEYKGETKSFYPEEVSSMVLTKMKEIAEAYLGKTVTNAVVTVPAYFNDS 153
V+N + +P +Q G TK+F PEE+S+MVL KM++IAEAYLGK + NAVVTVPAYFND+
Sbjct: 452 VINKSNKPHIQALVSGATKTFAPEEISAMVLGKMRDIAEAYLGKKIDNAVVTVPAYFNDA 273
Query: 154 QRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKVG 190
QRQATKDAGTIAGLNV+RIINEPTAAAIAYGLDK+ G
Sbjct: 272 QRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKRDG 162
Score = 82.4 bits (202), Expect(2) = 2e-55, Method: Compositional matrix adjust.
Identities = 36/50 (72%), Positives = 46/50 (92%)
Frame = -1
Query: 193 RNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNHFI 242
N+L+FDLGGGTFDVS+LTI++G+FEV +T GDTHLGGEDFD R+++HFI
Sbjct: 159 ENILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMDHFI 10
>27378
Length = 410
Score = 199 bits (507), Expect = 2e-51, Method: Compositional matrix adjust.
Identities = 96/124 (77%), Positives = 107/124 (86%)
Frame = -1
Query: 244 EFKRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITRARFE 303
EFKRK+KKD+ N RA+RRLRTA ERAKRTLSSST+A+IE+D+L+EG DFYT I+RARFE
Sbjct: 410 EFKRKYKKDLRSNPRALRRLRTAAERAKRTLSSSTEATIEVDALFEGHDFYTKISRARFE 231
Query: 304 ELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELNKSI 363
EL ADLFR TL PVEKAL DAK+DK IHDIVLVGGSTRIPK+Q LLQ FF GK LN SI
Sbjct: 230 ELCADLFRQTLAPVEKALNDAKMDKQMIHDIVLVGGSTRIPKVQNLLQQFFGGKSLNLSI 51
Query: 364 NPDE 367
NPDE
Sbjct: 50 NPDE 39
>21024
Length = 3220
Score = 189 bits (481), Expect = 2e-48, Method: Compositional matrix adjust.
Identities = 115/269 (42%), Positives = 158/269 (58%), Gaps = 2/269 (0%)
Frame = +3
Query: 3 KGPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQVAM 61
KG +GIDLGTT SCV + + + +++ N +G+RTTPS +AFT D ER+ G AK Q
Sbjct: 243 KGHVIGIDLGTTNSCVALMEGKQAKVLENSEGSRTTPSVIAFTKDGERISGMPAKRQAVT 422
Query: 62 NPTNTVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPEEVSS 121
N NT+ KRLIGRRF+D VQ DMK+ + +V A VE +G K + P +V +
Sbjct: 423 NAENTLSATKRLIGRRFEDPEVQKDMKNVSYKIVK-ASNGDAWVEAQG--KMYSPSQVGA 593
Query: 122 MVLTKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAI 181
VL KMKE AE+YLG V NAVVTVPAYFNDSQRQATKDAG I+GL + + +
Sbjct: 594 FVLMKMKETAESYLGSKVNNAVVTVPAYFNDSQRQATKDAGQISGLKCVACDQRTHSCSS 773
Query: 182 AYGLDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGE-DFDNRMVNH 240
+ + + + G +S + + + + T +TH E FDN MVN
Sbjct: 774 CFMAWTSLKIK**RCLI*AEGRLTSLSWRSRRECLKSNQPT--ETHSWEERTFDNYMVNF 947
Query: 241 FIAEFKRKHKKDISENKRAVRRLRTACER 269
+EFK++ DI+++ AV+RLR A E+
Sbjct: 948 LASEFKKEQGLDITKDPMAVQRLREAAEK 1034
Score = 124 bits (310), Expect = 1e-28, Method: Compositional matrix adjust.
Identities = 103/313 (32%), Positives = 150/313 (47%), Gaps = 17/313 (5%)
Frame = +1
Query: 166 GLNVLRIINEPTAAAIA--YGL-----DKKVGAER----NVLIFDLGGGTFDVSILTIED 214
G NVLR+INEPTAAA+A +G D V R ++ + D G ++
Sbjct: 727 G*NVLRVINEPTAAALALWHGQV*R*SDSGV*FRRRDV*HLYLGDPEG--------SV*S 882
Query: 215 GIFEVKSTAGDTHLGGEDFDNRMVNHFIAEFKRKHKKDISENKRAVRRLRTACERAKRTL 274
I + + G L + + RK K S+ + + R +++K L
Sbjct: 883 QINQRRHIPGRRGLLTTTWSTSWHQNL-----RKSKD*TSQRIQWLCRDYVRQQKSKIEL 1047
Query: 275 SSSTQASIEIDSLYEGID------FYTSITRARFEELNADLFRGTLDPVEKALRDAKLDK 328
SSS Q I + Y +D ++R++FE L L + T+ P +KAL+DA++ K
Sbjct: 1048 SSSLQTDINLP--YLTMDASGPKHMNLKLSRSKFESLVESLVKRTVGPCQKALQDAEVKK 1221
Query: 329 SQIHDIVLVGGSTRIPKIQKLLQDFFNGKELNKSINPDEXXXXXXXXXXXILSGDKSENV 388
S I +++LVGG +R+PK+Q +QD F G+ +KS+NPDE +L+GD V
Sbjct: 1222 SDIGEVILVGGMSRMPKVQSTVQDLF-GRTPSKSVNPDEAVAIGAAIQGGVLAGD----V 1386
Query: 389 QDXXXXXXXXXXXGIETAGGVMTVLIKRNXXXXXXXXXXXXXYSDNQPGVLIQVYEGERA 448
D GIET GGV T LI RN +D Q V I+V++GER
Sbjct: 1387 TDVLLLDVTPLSLGIETLGGVFTKLINRNTTIPTKKSQVFSTAADGQTQVEIKVHQGERE 1566
Query: 449 MTKDNNLLGKFEL 461
M DN LLG+F L
Sbjct: 1567 MANDNKLLGQFTL 1605
>30255
Length = 1761
Score = 178 bits (452), Expect = 3e-45, Method: Compositional matrix adjust.
Identities = 92/135 (68%), Positives = 94/135 (69%)
Frame = -1
Query: 328 KSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELNKSINPDEXXXXXXXXXXXILSGDKSEN 387
K IH+IVLVGGSTRIPKIQKLLQDFFNGKEL KSINPDE IL GDKSE
Sbjct: 1644 KPGIHEIVLVGGSTRIPKIQKLLQDFFNGKELCKSINPDEAVAYGACVQAAILHGDKSEE 1465
Query: 388 VQDXXXXXXXXXXXGIETAGGVMTVLIKRNXXXXXXXXXXXXXYSDNQPGVLIQVYEGER 447
VQD GIETAGGVMT LIKRN YSDNQPGVLIQVYEGER
Sbjct: 1464 VQDLLLLDVAPLSMGIETAGGVMTALIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGER 1285
Query: 448 AMTKDNNLLGKFELT 462
AMT+DNNLLGKFELT
Sbjct: 1284 AMTRDNNLLGKFELT 1240
>31218
Length = 322
Score = 95.1 bits (235), Expect = 6e-20, Method: Compositional matrix adjust.
Identities = 47/100 (47%), Positives = 68/100 (68%)
Frame = +2
Query: 225 DTHLGGEDFDNRMVNHFIAEFKRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEI 284
DTHLGGEDFD R+V++ + K+K +D+ + RA+ RLR + E+AKR LSS +++
Sbjct: 2 DTHLGGEDFDQRLVDYLVKLIKQKTGRDVRHDTRAMSRLRRSAEKAKRALSSQHSTKVDL 181
Query: 285 DSLYEGIDFYTSITRARFEELNADLFRGTLDPVEKALRDA 324
D + + T +TRA+FEELN DLFR TL V++AL D+
Sbjct: 182 DGVTSDLADLT-LTRAKFEELNTDLFRSTLTTVKRALEDS 298
>09881
Length = 600
Score = 90.9 bits (224), Expect = 1e-18, Method: Compositional matrix adjust.
Identities = 44/109 (40%), Positives = 64/109 (58%)
Frame = +3
Query: 3 KGPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMN 62
K A G+ LGT +C+ V++ GK + AND G+R+TP VAFT + +G +AK + N
Sbjct: 177 KMAAYGVHLGTCSACLAVYKDGKTSVAANDAGDRSTPCVVAFTACDAEVGASAKQGIVSN 356
Query: 63 PTNTVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGET 111
NTV + KR++G F+D V Q + P VVN +P +VE+K T
Sbjct: 357 VKNTVCNVKRILGLTFEDPVTQEYLASSPVKVVNQKNQPMFEVEFKERT 503
Score = 49.7 bits (117), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 27/54 (50%), Positives = 37/54 (68%)
Frame = +2
Query: 136 GKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKV 189
GK + +AV+ VP+ F+D QR A A + AG VLR+INE +AAA+AY L + V
Sbjct: 2 GKGIQDAVLAVPSDFSDKQRAAASAAASKAGFKVLRLINECSAAALAYDLGQTV 163
>20979
Length = 976
Score = 84.0 bits (206), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 45/140 (32%), Positives = 79/140 (56%), Gaps = 2/140 (1%)
Frame = +1
Query: 230 GEDFDNRMVNHFIAEFKRKHKKD--ISENKRAVRRLRTACERAKRTLSSSTQASIEIDSL 287
G + R+ +H F + K+ + +N RA+ +L ER K+ LS+++ +++ L
Sbjct: 70 GVEMTLRLRDHLAKVFNGQKKRSFKLEDNPRAMAKLLKEAERVKKVLSANSDHKAQVEGL 249
Query: 288 YEGIDFYTSITRARFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQ 347
EG DF ++R + EL DL P+E AL+ +++ +I +I+L+GG +R+P++Q
Sbjct: 250 VEGEDFAAKVSREDYLELIKDLLARVTKPMEDALKVSEITMPEITEIILMGGGSRVPRVQ 429
Query: 348 KLLQDFFNGKELNKSINPDE 367
+ L F +L KSIN DE
Sbjct: 430 EELLKFSGKSDLGKSINTDE 489
>26390
Length = 665
Score = 67.8 bits (164), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 34/61 (55%), Positives = 38/61 (62%)
Frame = +2
Query: 402 GIETAGGVMTVLIKRNXXXXXXXXXXXXXYSDNQPGVLIQVYEGERAMTKDNNLLGKFEL 461
GIET GGVMT LI R DNQ V IQVYEGER+ TKDN+LLG+F+L
Sbjct: 50 GIETVGGVMTTLIARGTTIPARKAKVFSTAQDNQDSVTIQVYEGERSRTKDNHLLGRFDL 229
Query: 462 T 462
T
Sbjct: 230 T 232
>12271
Length = 1762
Score = 62.8 bits (151), Expect = 3e-10, Method: Compositional matrix adjust.
Identities = 29/76 (38%), Positives = 48/76 (63%)
Frame = +2
Query: 292 DFYTSITRARFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQ 351
DF +TR ++ L DL PV++ L +++ ++I +I+L+GG +R+PKI ++L
Sbjct: 41 DFSCKVTRDKYLHLIQDLLDRVTLPVQQVLTASQITWAEITEIILMGGGSRLPKIHEILL 220
Query: 352 DFFNGKELNKSINPDE 367
D+ KEL KS+N DE
Sbjct: 221 DYSGKKELGKSLNTDE 268
>13684
Length = 438
Score = 55.5 bits (132), Expect = 5e-08, Method: Composition-based stats.
Identities = 25/60 (41%), Positives = 37/60 (61%)
Frame = -3
Query: 3 KGPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMN 62
K A G+ LGT +C+ V++ GK + AND G+R+TP VAFT + +G +AK + N
Sbjct: 181 KMAAYGVHLGTCSACLAVYKDGKTSVAANDAGDRSTPCVVAFTACDAEVGASAKQGIVSN 2
>03996
Length = 1105
Score = 50.8 bits (120), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 25/64 (39%), Positives = 40/64 (62%)
Frame = -2
Query: 304 ELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELNKSI 363
EL DL P+E AL+ +++ +I +I+L+GG +R+P++Q+ L F +L KSI
Sbjct: 1056 ELIKDLLARVTKPMEDALKVSEITMPEITEIILMGGGSRVPRVQEELLKFSGKSDLGKSI 877
Query: 364 NPDE 367
N DE
Sbjct: 876 NTDE 865
>24750
Length = 552
Score = 50.4 bits (119), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 21/24 (87%), Positives = 24/24 (100%)
Frame = +1
Query: 439 LIQVYEGERAMTKDNNLLGKFELT 462
++QVYEGERAMT+DNNLLGKFELT
Sbjct: 154 MLQVYEGERAMTRDNNLLGKFELT 225
>13300
Length = 453
Score = 45.4 bits (106), Expect = 4e-05, Method: Compositional matrix adjust.
Identities = 32/149 (21%), Positives = 70/149 (46%), Gaps = 17/149 (11%)
Frame = +3
Query: 154 QRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKVG---AERNVLIFDLGGGT-----F 205
+R+A A G+NVL+++ + A A+ YG+ ++ + + +D+G +
Sbjct: 3 ERRAIMTAADXVGINVLQLMTDSAAVALNYGVFRRKNFNTTAQYYMFYDMGATSTVATVV 182
Query: 206 DVSILTIEDGI-------FEVKSTAGDTHLGGEDFDNRMVNHFIAEFKRKHKKD--ISEN 256
++ +++G +K D LGG + R+ +H F + K+ + +N
Sbjct: 183 SYQVVKVKEGTRVESNPQLTIKGVGFDRTLGGLEMTLRLRDHLAKVFNGQKKRSFKLEDN 362
Query: 257 KRAVRRLRTACERAKRTLSSSTQASIEID 285
RA+ +L ER K+ LS+++ +++
Sbjct: 363 PRAMAKLLKEAERVKKVLSANSDHKAQVE 449
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000346424 | hsapiens_gene_ensembl | Focal adhesion
kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK) (Protein- tyrosine kinase
2). [Source:Uniprot/SWISSPROT;Acc:Q05397]
(877 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
06405 206 2e-53
21808 185 8e-47
11780 109 3e-41
09007 161 1e-39
04852 155 9e-38
07291 138 1e-32
14116 131 1e-30
17300 124 4e-30
20640 125 7e-29
07940 119 7e-27
08294 117 2e-26
18996 111 1e-24
14477 95 1e-19
17637 90 4e-18
22005 88 2e-17
13305 87 3e-17
18921 86 5e-17
17253 84 4e-16
01718 80 4e-15
00300 78 2e-14
19301 75 1e-13
12721 74 2e-13
14420 70 5e-12
27546 69 6e-12
30755 69 7e-12
13592 67 2e-11
31885 67 4e-11
09606 64 2e-10
13066 64 4e-10
00715 62 8e-10
07833 62 9e-10
13212 62 1e-09
19094 62 1e-09
29581 59 9e-09
19761 59 1e-08
14126 58 2e-08
21079 57 4e-08
04591 57 4e-08
01060 55 9e-08
18484 55 1e-07
07836 54 3e-07
03240 54 4e-07
15910 51 2e-06
01756 51 2e-06
26711 51 2e-06
01966 50 3e-06
25550 49 7e-06
12672 49 8e-06
32264 49 9e-06
21433 48 2e-05
01707 48 2e-05
26560 44 2e-04
04138 44 3e-04
01392 42 8e-04
12786 41 0.002
07933 40 0.004
03508 40 0.004
28157 39 0.008
37602 39 0.011
38046 38 0.015
18481 38 0.018
11185 38 0.022
00486 35 0.12
26009 35 0.17
27287 34 0.26
16708 34 0.27
15741 34 0.29
27405 34 0.30
02638 33 0.35
21210 33 0.39
25019 32 1.5
06601 30 5.5
>06405
Length = 1965
Score = 206 bits (525), Expect = 2e-53, Method: Compositional matrix adjust.
Identities = 109/303 (35%), Positives = 165/303 (54%), Gaps = 2/303 (0%)
Frame = +1
Query: 228 PSTRDYEIQRERIELGRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFL 287
P +EI+R I + +G GQ+GDV++ ++ VA+KT K T FL
Sbjct: 229 PEPDRWEIERTEIAMKHRLGGGQYGDVYEAMWKRYNK---IVAVKTLKEDTM--ALNDFL 393
Query: 288 QEACHYTSLHWNWCRYISDPNVDCPDPRNAEVTMRQFDHPHIVKLIGVIT-ENPVWIIME 346
+EA M++ HP++V+L+GV T E P +I+ E
Sbjct: 394 EEAA----------------------------IMKEMKHPNLVQLLGVCTREPPFYIVTE 489
Query: 347 LCTLGELRSFLQVRKYSLDLASLILY-AYQLSTALAYLESKRFVHRDIAARNVLVSSNDC 405
G L +L+ + + ++Y A Q+++ +AYLE+K F+HRD+AARN LV+ ++
Sbjct: 490 FMPHGNLLDYLRSSTREENGPTALMYMATQIASGMAYLETKNFIHRDLAARNCLVADSNM 669
Query: 406 VKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHG 465
VK+ DFGL+R M+D TY K PIKW APE + F RF++ SD+W FGV +WE+ +G
Sbjct: 670 VKVADFGLARLMKDDTYTAHIGAKFPIKWTAPEGLAFNRFSTRSDIWAFGVLLWELATYG 849
Query: 466 VKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTI 525
+ P+ GV+ +V +E G R+ PP P +Y LM KCW +DP RP F E+ L +
Sbjct: 850 MSPYPGVELTEVYHLLERGYRMERPPGTPADVYILMLKCWQWDPKDRPTFKEIHFLLENM 1029
Query: 526 LEE 528
E+
Sbjct: 1030FEK 1038
>21808
Length = 1011
Score = 185 bits (469), Expect = 8e-47, Method: Compositional matrix adjust.
Identities = 85/207 (41%), Positives = 129/207 (62%), Gaps = 1/207 (0%)
Frame = +1
Query: 321 MRQFDHPHIVKLIGVITEN-PVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTA 379
M++ HP +++L V T++ P++II EL G L FLQ + L L +LI Q++
Sbjct: 94 MKKLRHPKLIQLYAVCTQDDPIFIITELMKNGSLLEFLQGKGRVLKLPALIDIGAQIACG 273
Query: 380 LAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPES 439
+AYLES+ ++HRD+AARN+LVS N+ VK+ DFGL+R +++ Y + PIKW APE+
Sbjct: 274 MAYLESQNYIHRDLAARNILVSDNNTVKIADFGLARVIKEDEYEARVGARFPIKWTAPEA 453
Query: 440 INFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYS 499
N+ RFT SDVW FG+ + E + +G P+ G+ N +V+ ++E+G R+P PP CP LY
Sbjct: 454 ANYNRFTIKSDVWSFGILLTETVTYGRVPYPGMTNAEVLHQVEHGYRMPCPPGCPKPLYD 633
Query: 500 LMTKCWAYDPSRRPRFTELKAQLSTIL 526
+M +CW + RP + IL
Sbjct: 634 IMLECWRKEEMERPHLRNPAMEAGGIL 714
>11780
Length = 1713
Score = 109 bits (273), Expect(2) = 3e-41, Method: Compositional matrix adjust.
Identities = 71/207 (34%), Positives = 104/207 (50%), Gaps = 1/207 (0%)
Frame = +3
Query: 235 IQRERIELGRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEACHYT 294
I + +E+G IG+G FGDV++G+Y VAIK K+ D + FLQEA T
Sbjct: 588 IAXQDLEIGEAIGKGDFGDVYKGMYRGQ-----PVAIKQLKD--KDRGEQSFLQEASVMT 746
Query: 295 SLHWNWCRYISDPNVDCPDPRNAEVTMRQFDHPHIVKLIGVITENPVWIIMELCTLGELR 354
SL H ++V+LIGV+ ++++ E G L
Sbjct: 747 SLR----------------------------HDNLVRLIGVVLGETIFLVTEFMGKGNLV 842
Query: 355 SFLQVRKYS-LDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGL 413
+L+ R S + I +A A+ YLESKR VHRD+AARNVLV + K+ DFGL
Sbjct: 843 EYLRSRGRSVITKKDQINFATDTCAAMEYLESKRLVHRDLAARNVLVHDDGKAKVSDFGL 1022
Query: 414 SRYMEDSTYYKASKGKLPIKWMAPESI 440
+++ + + + K PIKW APE++
Sbjct: 1023AKFGD----FSQTSVKFPIKWTAPEAL 1091
Score = 78.2 bits (191), Expect(2) = 3e-41, Method: Compositional matrix adjust.
Identities = 33/81 (40%), Positives = 49/81 (60%)
Frame = +1
Query: 444 RFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTK 503
+FTS SD+W FG+ +WEI G P+ + DV+ +E G R+ P CPP +YS+M +
Sbjct: 1102 KFTSKSDMWSFGILLWEIYSFGRVPYPRIPLTDVVMHVERGYRMEAPEGCPPEIYSIMKQ 1281
Query: 504 CWAYDPSRRPRFTELKAQLST 524
W DP+ RP F + A+L+
Sbjct: 1282 AWELDPNERPTFKSVLARLNN 1344
>09007
Length = 1440
Score = 161 bits (407), Expect = 1e-39, Method: Compositional matrix adjust.
Identities = 97/302 (32%), Positives = 148/302 (49%), Gaps = 11/302 (3%)
Frame = -1
Query: 235 IQRERIELGRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEACHYT 294
I ++ + L + +G+G FG V Q I+ + + VA+K C S K QE T
Sbjct: 888 ISKDCVALSKSLGQGHFGTVRQAIWTAESGEKVQVAVK----CLSKDKIHKDGQEFLKET 721
Query: 295 SLHWNWCRYISDPNVDCPDPRNAEVTMRQFDHPHIVKLIGVITENPVWIIMELCTLGELR 354
++ M+ DH +IV++ GV+ +N IM + L +R
Sbjct: 720 AI------------------------MQMLDHENIVRVYGVVMDNGA-DIMLVTELAPMR 616
Query: 355 SFLQVRK-----YSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLG 409
S L+ K + L ++ Q+ ++YLESKR VHRD+AARN+L+ S VK+
Sbjct: 615 SLLECVKEVSARVDFSVPRLCDFSQQVCDGMSYLESKRLVHRDLAARNILLFSKSKVKIS 436
Query: 410 DFGLSRYMEDSTYYKASKGKL----PIKWMAPESINFRRFTSASDVWMFGVCMWEILMHG 465
D G+S + Y S+ + + W APES F+SASDVW FGV +WE HG
Sbjct: 435 DVGVSGALGAGKEYYQSQQTIHLQNAVAWCAPESFRNLCFSSASDVWAFGVLLWEFFTHG 256
Query: 466 VKPFQGVKNNDVIGRIE--NGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLS 523
+P+ G+ ++ ++ +RL P CP Y++M KCW +P RRP F++L L
Sbjct: 255 FQPWAGLNGQQIMEAVDAPQSQRLEQPDLCPKEYYAVMLKCWEQEPQRRPTFSQLFLTLP 76
Query: 524 TI 525
I
Sbjct: 75 QI 70
>04852
Length = 1462
Score = 155 bits (391), Expect = 9e-38, Method: Compositional matrix adjust.
Identities = 80/227 (35%), Positives = 126/227 (55%), Gaps = 26/227 (11%)
Frame = +1
Query: 326 HPHIVKLIGVITEN-PVWIIMELCTLGELRSFLQ-----VRKYS---------------- 363
H +IV +G T+ P+W+I+E G LR FL+ + Y
Sbjct: 127 HINIVNFLGCCTQGGPLWVIVEFAKNGNLRDFLESCRDGINGYGKFVSPQDPGWYTKTPG 306
Query: 364 ---LDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDS 420
+ +L+ YA+Q++ + +L S++ +HRD+AARNVLV+ +K+ DFGLSR
Sbjct: 307 GHVIRRKNLLSYAFQIARGMEFLASRKCIHRDLAARNVLVTEEHVLKIADFGLSR--TGD 480
Query: 421 TYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGR 480
Y K S G+LP+KWMAPE++ R+T+ SDVW FGV +WEI G P+ + N ++ +
Sbjct: 481 YYKKRSGGRLPVKWMAPEALFDMRYTTKSDVWSFGVVLWEIFSLGGMPYASIPNEELYSK 660
Query: 481 -IENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTIL 526
+++ R+P P LY++M +CW PS RP F++L + +L
Sbjct: 661 LLDDAYRMPRPELASGNLYAIMERCWLNRPSDRPEFSQLVGHIDRLL 801
>07291
Length = 833
Score = 138 bits (347), Expect = 1e-32, Method: Compositional matrix adjust.
Identities = 62/164 (37%), Positives = 101/164 (61%), Gaps = 2/164 (1%)
Frame = +1
Query: 364 LDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYY 423
L + L+ + Q++ +AYL+ + VHR++AARN +V+ + ++L D+G++ + +YY
Sbjct: 40 LTVVQLLDFGRQIADGMAYLQEVKVVHRNLAARNCIVTEDGRLQLSDYGVTGSLFPQSYY 219
Query: 424 KA--SKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRI 481
A S + +KWMAPE+I+ F+S SDVW FGV +WE+L G+ P+ V+N+ ++ +
Sbjct: 220 TADDSPARDLVKWMAPETIDNFHFSSKSDVWAFGVVLWELLTRGITPYPDVENSSLLPYL 399
Query: 482 ENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTI 525
+ G R+ P P +Y +MT CW P +RP F EL QL T
Sbjct: 400 KEGHRMKKPKQSPEPVYEMMTACWNESPEQRPDFAELNDQLKTF 531
>14116
Length = 1017
Score = 131 bits (329), Expect = 1e-30, Method: Compositional matrix adjust.
Identities = 84/287 (29%), Positives = 140/287 (48%), Gaps = 19/287 (6%)
Frame = -1
Query: 198 EKQGMRTHAVSVSETDDYAEIID------------EEDTYTMPSTRDYEIQRERIELGRC 245
+ G RT+ + E +DY +D +ED + I RE + +G
Sbjct: 789 DSNGTRTYNLEARE-NDYFNRLDVQGAEAMPLLHIDEDMMKLIENESLLIDREFLTMGEE 613
Query: 246 IGEGQFGDVHQGIYMSPENPA-LAVAIKTCKNCTSDSVR-EKFLQEACHYTSLHWNWCRY 303
IG+G FG V +G PE + VA+KT N + + FLQEA
Sbjct: 612 IGKGNFGCVKRGFLTLPEQKGDILVAVKTLHNNNPREIELQSFLQEA------------- 472
Query: 304 ISDPNVDCPDPRNAEVTMRQFDHPHIVKLIGV---ITENPVWIIMELCTLGELRSFLQVR 360
+ M+ F H +++ LIG+ + + P+ +++ G+L ++++
Sbjct: 471 ---------------LIMKDFHHSNVLTLIGICLNLDDMPL-VVLPFMKHGDLLTYIRDD 340
Query: 361 KYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDS 420
++ + LI+Y ++ + YL +FVHRD+AARN ++ + VK+ DFGL+R + +
Sbjct: 339 QHQPTIKDLIMYGVDIARGMDYLAGLKFVHRDLAARNCMLDEDFHVKVADFGLARDIYEK 160
Query: 421 TYYKA--SKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHG 465
YY + K KLP+KWMA ES+ + S +DVW +GV +WE+L G
Sbjct: 159 EYYSSENKKAKLPVKWMALESLEKGNYDSKTDVWSYGVVLWELLTRG 19
>17300
Length = 480
Score = 124 bits (310), Expect(2) = 4e-30, Method: Compositional matrix adjust.
Identities = 56/117 (47%), Positives = 78/117 (66%), Gaps = 3/117 (2%)
Frame = +1
Query: 376 LSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTY---YKASKGKLPI 432
+S+ + L +VHRD+AARN+LV+ K+ DFGLSR +E T Y GK+P+
Sbjct: 1 ISSGMGXLADMGYVHRDLAARNILVNEILVCKVADFGLSREIESDTTEGAYTTKGGKIPV 180
Query: 433 KWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPM 489
+W APE+I +R+FTSASDVW FGV MWE++ +G +P+ N DVI +E G RLP+
Sbjct: 181 RWTAPEAIAYRKFTSASDVWSFGVVMWEVMSYGERPYWNWSNQDVIKAVEKGYRLPL 351
Score = 26.9 bits (58), Expect(2) = 4e-30, Method: Compositional matrix adjust.
Identities = 10/35 (28%), Positives = 18/35 (51%)
Frame = +2
Query: 492 NCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTIL 526
+CP L+ LM W + S RP+ + + L ++
Sbjct: 356 DCPEALHQLMLDAWQKERSHRPKMSMVVKTLDKLI 460
>20640
Length = 1492
Score = 125 bits (314), Expect = 7e-29, Method: Compositional matrix adjust.
Identities = 55/139 (39%), Positives = 85/139 (61%), Gaps = 1/139 (0%)
Frame = +1
Query: 388 FVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASK-GKLPIKWMAPESINFRRFT 446
+VHRD+A RN LV + VK+ DFGL+R + YY+ S+ +PI+WM E+I + +F+
Sbjct: 7 YVHRDLATRNCLVGHDLVVKISDFGLARSVHSVDYYRGSEHDAIPIRWMPLEAILYNKFS 186
Query: 447 SASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWA 506
+ SDVW FGV +WEI ++P+ G+ + +V+ ++ G+ L P PP +Y LM +CW
Sbjct: 187 TQSDVWSFGVVLWEIFAFALQPYYGLTHEEVVRFVKEGKVLACPERTPPPMYELMKQCWH 366
Query: 507 YDPSRRPRFTELKAQLSTI 525
P+ RP F L L +
Sbjct: 367 RRPATRPSFHTLHKTLENM 423
>07940
Length = 1336
Score = 119 bits (297), Expect = 7e-27, Method: Compositional matrix adjust.
Identities = 54/111 (48%), Positives = 77/111 (69%), Gaps = 1/111 (0%)
Frame = -3
Query: 369 LILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYY-KASK 427
LI YAYQ++ + YL SK+ +HRD+AARNVLV+ +K+ DFGL+R ++ YY K +
Sbjct: 341 LISYAYQVARGMEYLASKQCIHRDLAARNVLVAEEYVLKIADFGLTRNLQQFDYYRKTTD 162
Query: 428 GKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVI 478
G+LP+KWMAPE++ R++TS SDVW +GV +WEI G P+ V D+
Sbjct: 161 GRLPVKWMAPEALFDRKYTSKSDVWSYGVLLWEIFTLGGNPYPSVPVEDLF 9
Score = 46.2 bits (108), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 37/141 (26%), Positives = 59/141 (41%), Gaps = 3/141 (2%)
Frame = -3
Query: 221 EEDTYTMPSTRDYEIQRERIELGRCIGEGQFGDVHQGIYMS--PENPALAVAIKTCKNCT 278
E Y +P +E RER+ LG +GEG FG V +G M +N ++ VA+K K
Sbjct: 893 EVSEYDLPLDAKWEFPRERLVLGDRLGEGAFGLVMKGEAMGIFKDNNSVTVAVKMLKEDA 714
Query: 279 SDSVREKFLQEACHYTSLHWNWCRYISDPNVDCPDPRNAEVTMRQFDHPHIVKLIGVITE 338
+D ++E E+ H +I+ L+G T+
Sbjct: 713 TDREMMDLIRE---------------------------MEMMKVIGKHKNIINLLGCCTQ 615
Query: 339 -NPVWIIMELCTLGELRSFLQ 358
+++I+E G LR FL+
Sbjct: 614 RGALYVIVEFAPHGNLRDFLK 552
>08294
Length = 1849
Score = 117 bits (293), Expect = 2e-26, Method: Compositional matrix adjust.
Identities = 67/209 (32%), Positives = 113/209 (54%), Gaps = 12/209 (5%)
Frame = +2
Query: 327 PHIVKLIGVITE-NPVWIIMELCTLGELRSFL-----------QVRKYSLDLASLILYAY 374
P+IV +GV E P ++I E C G+L+ FL R +L L+ +
Sbjct: 887 PNIVHFMGVCREAEPHFLITEYCDWGDLKQFLLATRNDNGRGRGTRVPALALSQKLGMGQ 1066
Query: 375 QLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKW 434
Q++ + L ++ VH D+AARNVL++S +K+ LS + S YY + +P++W
Sbjct: 1067 QVAAGMEALSNQGLVHGDLAARNVLLTSRMQLKVARPALSGDVYASEYYPLHQRLVPLRW 1246
Query: 435 MAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCP 494
+ PE + T+ DVW FGV +WE+L P++ + + +V+ +++ + P+ P
Sbjct: 1247 LPPEGVLEDSATTCGDVWAFGVFLWEVLQLADLPYRLMSDEEVLRSLQHSQAALDSPDAP 1426
Query: 495 PTLYSLMTKCWAYDPSRRPRFTELKAQLS 523
P L SL+ +C A PS+RP F+E+ + LS
Sbjct: 1427 PALLSLLQRCTAQQPSQRPPFSEICSVLS 1513
>18996
Length = 491
Score = 111 bits (277), Expect = 1e-24, Method: Compositional matrix adjust.
Identities = 56/136 (41%), Positives = 82/136 (60%), Gaps = 6/136 (4%)
Frame = +2
Query: 389 VHRDIAARNVLVSSNDCVKLGDFGLSRYME-DSTYYKASKGKLPIKWMAPESINFRRFTS 447
+HRD+AARN+LV + CVK+ DFGL+++ D YY S+ +PIKW +PE+I +F+S
Sbjct: 2 IHRDLAARNILVDRS-CVKISDFGLAQFANADGYYYGISQRDIPIKWYSPEAIETCKFSS 178
Query: 448 ASDVWMFGVCMWEILMHG----VKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYS-LMT 502
SDVW +GV ++E+ G + P + + + R+ GERLP P C +YS LM
Sbjct: 179 YSDVWSYGVTLFEMFSRGEIPNLLPGHDLTQEEFLNRLRKGERLPKPELCSDFVYSELMR 358
Query: 503 KCWAYDPSRRPRFTEL 518
CW P RP F ++
Sbjct: 359 PCWHEMPKSRPTFHQI 406
>14477
Length = 493
Score = 94.7 bits (234), Expect = 1e-19, Method: Compositional matrix adjust.
Identities = 63/196 (32%), Positives = 101/196 (51%), Gaps = 1/196 (0%)
Frame = -1
Query: 234 EIQRERIELGRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEACHY 293
+IQ + ++LG G FG V +G+ ++ + VAIK KN D
Sbjct: 490 QIQMDELKLG----AGNFGSVMKGVC-RLDDREIPVAIKVLKNADLD------------- 365
Query: 294 TSLHWNWCRYISDPNVDCPDPRNAEVTMRQFDHPHIVKLIGVITENPVWIIMELCTLGEL 353
P+V + AEV M++ DH HIV+LIG+ + +++EL LG L
Sbjct: 364 -------------PSVQSELIKEAEV-MKKMDHMHIVRLIGLCEGETMMLVLELAKLGPL 227
Query: 354 RSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGL 413
FL K+ L L +++ +Q+S + YLE+ +FVHRD+AARN+L+ K+ DFG+
Sbjct: 226 NKFLPKNKH-LPLWNILELMWQVSQGMEYLEANKFVHRDLAARNILLCDEHFAKISDFGM 50
Query: 414 SRYM-EDSTYYKASKG 428
S+ + ++ YY A +
Sbjct: 49 SKTLSRENNYYMAQEA 2
>17637
Length = 447
Score = 90.1 bits (222), Expect = 4e-18, Method: Compositional matrix adjust.
Identities = 46/128 (35%), Positives = 70/128 (54%), Gaps = 1/128 (0%)
Frame = +1
Query: 397 NVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKL-PIKWMAPESINFRRFTSASDVWMFG 455
N ++ VKL D LSR + Y G+ PIKW++ E++ + SDVW FG
Sbjct: 1 NCVIDDQLRVKLTDSALSRDLFSGDYNCLGDGEYRPIKWLSLEALQKSHYNEGSDVWSFG 180
Query: 456 VCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRF 515
V MWE+ G P+ + ++ +++G RL P NCP L+++M CWA P+ RP F
Sbjct: 181 VLMWEMCTLGKLPYAEIDPYEMEHYLKDGYRLAQPFNCPDELFTIMAYCWASMPAERPSF 360
Query: 516 TELKAQLS 523
++L+ LS
Sbjct: 361 SQLQICLS 384
>22005
Length = 873
Score = 87.8 bits (216), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 61/187 (32%), Positives = 93/187 (49%), Gaps = 45/187 (24%)
Frame = +1
Query: 321 MRQFDHPHIVKLIGVIT-ENPVWIIMELCTLGELRSFLQV---RKYSL------------ 364
M FDHP+IVKL+GV P+ ++ E + G+L FL++ Y+L
Sbjct: 172 MADFDHPNIVKLLGVCAIGKPMCLLFEFMSKGDLNDFLRLCSPENYNLPVSRSQNLVVDL 351
Query: 365 ----------------------DLASLI-----LY-AYQLSTALAYLESKRFVHRDIAAR 396
D + ++ LY + Q+S +AYL K +VHRD+A R
Sbjct: 352 EDGLRVEVEAEECEKDTQSEDRDCSGMLXTKDQLYISQQISAGMAYLAQKDYVHRDLATR 531
Query: 397 NVLVSSNDCVKLGDFGLSRYMEDSTYYKAS-KGKLPIKWMAPESINFRRFTSASDVWMFG 455
V + + DFGL+R + YY+ S + +PI+WM E+I + +F++ SDVW FG
Sbjct: 532 TVXSRTT*-S*ISDFGLARSVHSVDYYRGSEQDAIPIRWMPLEAILYSKFSTQSDVWSFG 708
Query: 456 VCMWEIL 462
V +WEIL
Sbjct: 709 VVLWEIL 729
>13305
Length = 549
Score = 87.0 bits (214), Expect = 3e-17, Method: Composition-based stats.
Identities = 37/100 (37%), Positives = 57/100 (57%)
Frame = +2
Query: 429 KLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLP 488
++PI+WMA ES+ +T+ SDVW FGV +WEI G P+ + +++G RL
Sbjct: 8 RVPIRWMAVESLFNNTYTTQSDVWSFGVVLWEIFTLGGTPYSSTDTQQLFAFLKDGYRLK 187
Query: 489 MPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEE 528
P C Y++M +CW + RRP F EL +L +L++
Sbjct: 188 RPKLCDQNTYAMMLQCWNENAQRRPTFPELCGRLQRMLDD 307
>18921
Length = 697
Score = 86.3 bits (212), Expect = 5e-17, Method: Compositional matrix adjust.
Identities = 56/181 (30%), Positives = 90/181 (49%), Gaps = 4/181 (2%)
Frame = +2
Query: 321 MRQFDHPHIVKLIGVITENP-VWIIMELCTLGELRSFLQVRKYSL---DLASLILYAYQL 376
M+Q D +IVK G +N +WI+ME C G + +++R +L ++A+++ Y +
Sbjct: 176 MQQCDSKYIVKYYGSYFKNTDLWIVMEYCGAGSVSDIMRLRNKTLVEREIATILYYTLK- 352
Query: 377 STALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMA 436
L YL S+R +HRDI A N+L+++ KL DFG++ + D+ + + P WMA
Sbjct: 353 --GLXYLHSRRKIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTPY-WMA 523
Query: 437 PESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPT 496
PE I + +D+W G+ E + G P I G+ P N PP
Sbjct: 524 PEVIQEIGYDCVADIWSLGITALE-MAEGKPPVMETS-------IL*GQSS*FPTNAPPP 679
Query: 497 L 497
L
Sbjct: 680 L 682
>17253
Length = 483
Score = 83.6 bits (205), Expect = 4e-16, Method: Composition-based stats.
Identities = 56/180 (31%), Positives = 88/180 (48%), Gaps = 14/180 (7%)
Frame = -1
Query: 269 VAIKTCKNCTSDSVREKFLQEACHYTSLHWNWCRYISDPNVDCPDPRNAEVTMRQFDHPH 328
VA+KT +D+ + +FL+E L PR HP+
Sbjct: 459 VAVKTHNEAATDAEKSEFLRELSIMRKL-----------------PR----------HPN 361
Query: 329 IVKLIGVIT-ENPVWIIMELCTLGELRSFLQVRK---------YSLDLASLILYAYQLST 378
+V +G T +P I+ME C G+L SFL+ R+ + DL + +++ L
Sbjct: 360 VVSFMGCCTMSDPALILMEFCCHGDLLSFLRKRRPDRTVFLTSTANDLTARDFFSFALHV 181
Query: 379 A--LAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDS--TYYKASKGKLPIKW 434
A +A++ + + VHRD+AARNVL+S + K+ DFGLSR + D Y S+ LP++W
Sbjct: 180 ARGMAHVANNKIVHRDVAARNVLISERNVCKVSDFGLSRRVGDQNDVYEIVSRRPLPLRW 1
>01718
Length = 959
Score = 80.1 bits (196), Expect = 4e-15, Method: Compositional matrix adjust.
Identities = 62/224 (27%), Positives = 94/224 (41%), Gaps = 14/224 (6%)
Frame = +3
Query: 321 MRQFDHPHIVKLIGV-ITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTA 379
+ + H +I++ +GV + E + + E G L L+ + L I L+
Sbjct: 294 LNRLQHANILRFMGVCVHEGQLHALTEYIPSGNLEQLLEKKDEELPWTQRIQLTLGLARG 473
Query: 380 LAYLESKRFVHRDIAARNVLVSSNDC----VKLGDFGLSRYMEDSTYYKASKGKLPI--- 432
L YL S RF+HRD+ ++N+L+ D + DFGL+ + D K KLP
Sbjct: 474 LDYLHSTRFIHRDLTSKNILIRREDNHGYHAVIADFGLATKIPDPL----DKEKLPTVGS 641
Query: 433 -KWMAPESINFRRFTSASDVWMFGVCMWEILMH-----GVKPFQGVKNNDVIGRIENGER 486
WMAPE +N + +D++ G+ M EI + P D + E
Sbjct: 642 PYWMAPEVLNGHFYNERADLFSVGIIMCEITARIPADPDIMPRMNNFGVDYVALSE---- 809
Query: 487 LPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEK 530
M CP L KC DP +RPR E+ L I + K
Sbjct: 810 --MISYCPLDYLQLAFKCCQVDPQKRPRGVEIIEWLEKIFKNLK 935
>00300
Length = 2318
Score = 77.8 bits (190), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 74/302 (24%), Positives = 124/302 (41%), Gaps = 11/302 (3%)
Frame = -1
Query: 228 PSTRDYEIQRERIEL----GRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVR 283
P DY I R+ G IGEGQFG V+ + MS +A+K K +D +
Sbjct: 1700 PREPDYRINVRRVNFRWQRGNKIGEGQFGKVYTAVNMST---GELMALKEMKFQPNDLQQ 1530
Query: 284 EKFLQEACHYTSLHWNWCRYISDPNVDCPDPRNAEVTMRQFDHPHIVKLIGV-ITENPVW 342
L+E C + H ++VK GV + ++ +
Sbjct: 1529 ---LREMCDEIKI------------------------FEGIQHENLVKYYGVEVHKDEML 1431
Query: 343 IIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSS 402
+ ME C G + + K L + Y ++ A+ +L VHRDI N+ ++S
Sbjct: 1430 MFMEYCDTGTIE---EAAKMGLPEYLIRRYTREIVLAVNHLHENSIVHRDIKGANIFLTS 1260
Query: 403 NDCVKLGDFGLSRYMEDSTYYKASKGKL--PIKWMAPESINFRR---FTSASDVWMFGVC 457
N VKLGDFG S ++ T L +MAPE + A+D+W G
Sbjct: 1259 NGHVKLGDFGCSVKLKSHTTMPGEFHNLVGTTAYMAPEVFTQNDQGGYGRAADIWSLGCV 1080
Query: 458 MWEILMHGVKPFQGVKNN-DVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFT 516
+ E+ G +P+ + NN ++ ++ G + +P + + +DP++R +
Sbjct: 1079 VIEMAT-GKRPWHDLDNNYQIMYKVGIGHKPAVPDSLSVEGKHFLDLIMCHDPAQRALAS 903
Query: 517 EL 518
+L
Sbjct: 902 QL 897
>19301
Length = 712
Score = 75.1 bits (183), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 37/95 (38%), Positives = 61/95 (64%), Gaps = 1/95 (1%)
Frame = +2
Query: 321 MRQFDHPHIVKLIGVITENPVW-IIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTA 379
+R+ +HP+I+ GV T+ P + IIME C G+L L+ K + A ++ ++ Q+++
Sbjct: 431 LRKLNHPNIISFKGVCTQAPCYCIIMEYCPYGQLYEVLRDGK-EIPPALVLDWSKQIASG 607
Query: 380 LAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLS 414
+ YL S + +HRD+ + NVLV+ ND VK+ DFG S
Sbjct: 608 MNYLHSHKIIHRDLKSPNVLVAKNDVVKISDFGTS 712
>12721
Length = 821
Score = 73.9 bits (180), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 55/205 (26%), Positives = 88/205 (42%), Gaps = 8/205 (3%)
Frame = +1
Query: 316 NAEVTMRQFDHPHIVKLIG-VITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAY 374
N V MR + HP+IV++ + + +W++ME G L V +D +
Sbjct: 223 NEVVVMRDYHHPNIVEMYNSYLVNDELWVVMEFMEGGALTDI--VTNNRMDEVQIATVCR 396
Query: 375 QLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKW 434
ALA+L + +HRDI + ++L+S + VKL DFG + + S P W
Sbjct: 397 ACLKALAFLHANGVIHRDIKSDSILLSHDGKVKLXDFGFCAQVTQDLQKRKSLVGTPY-W 573
Query: 435 MAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPP--- 491
MAPE I+ + D+W G+ + E ++ PF + RI + MPP
Sbjct: 574 MAPEVISRLPYGPEVDIWSLGIMVME-MIDAEPPFFNEPPLQAMRRIRD-----MPPPKL 735
Query: 492 ----NCPPTLYSLMTKCWAYDPSRR 512
P L + + DP +R
Sbjct: 736 RNTHKISPRLQGFIDRMLVRDPHQR 810
>14420
Length = 528
Score = 69.7 bits (169), Expect = 5e-12, Method: Compositional matrix adjust.
Identities = 42/155 (27%), Positives = 73/155 (47%), Gaps = 1/155 (0%)
Frame = +2
Query: 316 NAEVTMRQFDHPHIVK-LIGVITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAY 374
N + MR+ +P+IV L + +W++ME G L V + +D +
Sbjct: 47 NEILVMRENQNPNIVNYLDSYLVGEELWVVMEFLAGGSLTDV--VTETCMDEGQIAAVCR 220
Query: 375 QLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKW 434
+ AL +L + +HRDI + N+L+ + VKL DFG + +++ P W
Sbjct: 221 ECLQALEFLHENQVIHRDIKSDNILLGMDGSVKLTDFGFCAQLSPEQSKRSTMVGTP-YW 397
Query: 435 MAPESINFRRFTSASDVWMFGVCMWEILMHGVKPF 469
MAPE + +++ D+W GV E ++ G P+
Sbjct: 398 MAPEVVTRKQYGPTVDIWSLGVMCIE-MIEGEPPY 499
>27546
Length = 426
Score = 69.3 bits (168), Expect = 6e-12, Method: Composition-based stats.
Identities = 35/108 (32%), Positives = 61/108 (56%), Gaps = 1/108 (0%)
Frame = -1
Query: 314 PRNAEVTMRQFDHPHIVKLIGVITENP-VWIIMELCTLGELRSFLQVRKYSLDLASLILY 372
PR E+ R DHP+I+++ ++ P ++I M G++ S ++ + +D A ++
Sbjct: 336 PRELEILTR-LDHPNIIQIHSILQRGPKIFIFMRYAEKGDMLSHIK-KTGPIDEAQTKVW 163
Query: 373 AYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDS 420
+Q++ AL YL S HRD+ N+L+S VK+ DFG +RY D+
Sbjct: 162 FFQMAKALQYLHSHDIAHRDLKCENILLSKRLNVKIADFGFARYCRDA 19
>30755
Length = 1137
Score = 69.3 bits (168), Expect = 7e-12, Method: Compositional matrix adjust.
Identities = 44/143 (30%), Positives = 76/143 (53%), Gaps = 1/143 (0%)
Frame = +2
Query: 371 LYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKL 430
Y ++ +AL YL S+ ++RD+ N+L+ + +K+ DFGL + ED TY + +K
Sbjct: 44 FYGAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCK--EDITYGRTTKTFC 217
Query: 431 PI-KWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPM 489
+++APE ++ + A D W GV M+E++ G PF +++DV+ + E +
Sbjct: 218 GTPEYLAPEVLDDNDYGRAVDWWGTGVVMYEMIC-GRLPFYN-RDHDVLFTLILVEDVKF 391
Query: 490 PPNCPPTLYSLMTKCWAYDPSRR 512
P N SL++ A DP R
Sbjct: 392 PRNITDEAKSLLSGLLAKDPRNR 460
>13592
Length = 980
Score = 67.4 bits (163), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 55/204 (26%), Positives = 96/204 (47%), Gaps = 8/204 (3%)
Frame = +2
Query: 326 HPHIVKLIGV-ITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLE 384
H ++V+ G+ + + I MELC+ G L S +++ L A + QL + +A L
Sbjct: 158 HKNLVRYYGIEVHREELLIFMELCSEGTLESLVELTG-GLPEALSRRFTAQLLSGVAELH 334
Query: 385 SKRFVHRDIAARNV-LVSSNDCVKLGDFGLSRYMEDSTYYKAS-KGKLPIK-WMAPE--- 438
VHRDI N+ LV ++ +KLGDFG + ++ T +G + + +MAPE
Sbjct: 335 KHGIVHRDIKTANIFLVDGSNSLKLGDFGSAVKIQAHTTVPGELQGYVGTQAYMAPEVFT 514
Query: 439 SINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNN-DVIGRIENGERLPMPPNCPPTL 497
N +D+W G + E + G +P+ +N ++ ++ GE+ P +
Sbjct: 515 KTNSDGHGRLADIWSVGCVVVE-MASGKRPWAQFDSNFQIMFKVGMGEKPQAPESLSQEG 691
Query: 498 YSLMTKCWAYDPSRRPRFTELKAQ 521
+ + C +DP +R EL Q
Sbjct: 692 HDFIDHCLQHDPKQRLSAIELLEQ 763
>31885
Length = 529
Score = 66.6 bits (161), Expect = 4e-11, Method: Compositional matrix adjust.
Identities = 46/148 (31%), Positives = 77/148 (52%), Gaps = 6/148 (4%)
Frame = -2
Query: 321 MRQFDHPHIVKL-IGVITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTA 379
+ + DHP +V L E ++++++L G+LR +Q ++ S + Y QL+
Sbjct: 510 LTRLDHPFLVNLWYAFQDEEDLFMVVDLFLGGDLRYHMQ-QEVSFREDCVKFYLCQLALV 334
Query: 380 LAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPE- 438
L YL S++ VHRDI N+L+ + DF ++ +ED ++ G P +MAPE
Sbjct: 333 LDYLRSQKIVHRDIKPDNILLDEQGHCHVTDFNIATQLEDDELATSTSGTRP--YMAPEV 160
Query: 439 ---SINFRR-FTSASDVWMFGVCMWEIL 462
+IN RR + D W GV ++E+L
Sbjct: 159 YGVAINERRGYGFPVDWWSLGVSLFELL 76
>09606
Length = 1300
Score = 63.9 bits (154), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 62/254 (24%), Positives = 105/254 (41%), Gaps = 37/254 (14%)
Frame = -3
Query: 312 PDPRNAEVTMRQFDHPHIVKLIGVI-TENPVWIIMELCTLGELRSFLQVRKYSLDLASLI 370
P+ N HP++V+ T N +W+++ELCT G L L + + L S+
Sbjct: 998 PEVTNTVRMTHDISHPNVVQFHEWYETSNHLWLVVELCTGGSLADIL-AQDHHLPETSIR 822
Query: 371 LYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRY----MEDSTYYKAS 426
+ L T L Y+ S + D+ VL+ ++ +K DFGLS+ +E+ + A
Sbjct: 821 DFGIHLVTGLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAE 642
Query: 427 KG-------------KLPIK----WMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPF 469
G ++P +MAPE + SD+W G +E + G PF
Sbjct: 641 AGDQWNIQSAEEMMKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYE-MFSGHPPF 465
Query: 470 QGVKNNDVIGRIEN---------GERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTEL-- 518
G + ++ N G RL P+ P +L+ D +RR + L
Sbjct: 464 LGETYDITKDKVLNKEFPLPKVKGSRLSAKPS--PEFLNLLESLLQKDSTRRLSWASLVK 291
Query: 519 ----KAQLSTILEE 528
+ LS++++E
Sbjct: 290 HAFWQGGLSSLVKE 249
>13066
Length = 551
Score = 63.5 bits (153), Expect = 4e-10, Method: Compositional matrix adjust.
Identities = 43/152 (28%), Positives = 75/152 (49%), Gaps = 10/152 (6%)
Frame = +3
Query: 314 PRNAEVTMRQFDHPHIVKLIGVITENPV-WIIMELCTLGELRSFLQVRKYSLDLASLILY 372
PR ++ + + DHP+I+++ ++ P +I M G+L +++Q + + + I +
Sbjct: 120 PRELDL-LTKLDHPYIIQIHSILQRXPKNFIFMRFAERGDLLTYIQEVGFVKEKQAKIWF 296
Query: 373 AYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLS---------RYMEDSTYY 423
YQ++TAL YL S HRD+ N+L+SS+ VKL DFG + +YM +
Sbjct: 297 -YQMTTALNYLHSYDVAHRDLKCENILLSSHFNVKLADFGFACACITESGEKYMSRTYCG 473
Query: 424 KASKGKLPIKWMAPESINFRRFTSASDVWMFG 455
A+ I + AP + +D W G
Sbjct: 474 SAAYAAPEIVYGAPYA------PKVADAWSLG 551
>00715
Length = 1788
Score = 62.4 bits (150), Expect = 8e-10, Method: Compositional matrix adjust.
Identities = 52/221 (23%), Positives = 96/221 (43%), Gaps = 33/221 (14%)
Frame = +1
Query: 326 HPHIVKLIGVIT----ENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALA 381
H ++V ++G + E+ W+ ME L++ L + +D + + A Q++ L
Sbjct: 103 HVNVVSILGATSLHRFEDGAWLAMEYVGPLNLQTILNDHQQDIDSSMRLSLALQMARGLH 282
Query: 382 YLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYM-------------------EDSTY 422
YL S VH D+ N L++ + +++ DFG + E +
Sbjct: 283 YLHSINIVHLDLKPANCLLTRDLKLRIADFGCCHQLTPTGLDMGEREGGMAGNELELTPV 462
Query: 423 YKASKGKLP--IKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGR 480
A K +L + + APE + + + SDV+ G+ +W++ P++GV + V+ +
Sbjct: 463 QGAWKNELAGTLAYRAPELLKGLQPSVRSDVYSLGITLWQMCTRQ-GPYEGVPAHAVVYQ 639
Query: 481 IENGERLPMPPNCPPT--------LYSLMTKCWAYDPSRRP 513
+ + + P PP P T L T+CWA RP
Sbjct: 640 VVSKDLRPCPP--PSTEDDPFEVMFRDLYTQCWARRVEDRP 756
>07833
Length = 1504
Score = 62.0 bits (149), Expect = 9e-10, Method: Compositional matrix adjust.
Identities = 51/202 (25%), Positives = 93/202 (46%), Gaps = 7/202 (3%)
Frame = -3
Query: 321 MRQFDHPHIVKLIGVITENP-VWIIMELCTLGELRSFLQVRK-YSLDLASLILYAYQLST 378
+R F+HP+++ ++ + P + +I + G L + L +D + +A ++
Sbjct: 1457 LRIFNHPNVLPVLACCNQPPNLVLISQFMPFGSLYNTLHGESGIVVDQNQSLRFAMDIAR 1278
Query: 379 ALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKL-PIKWMAP 437
+ +L S + N L++S + D M D + KGK+ WMAP
Sbjct: 1277 GMEFLHSM-----EPTIPNFLLTSKHVMIDEDLTARINMADYCFSFHEKGKVYSPAWMAP 1113
Query: 438 ESINFRR---FTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIE-NGERLPMPPNC 493
E++ R T A+D+W F + MWE+ V PF + + +V ++ G R+ +PP
Sbjct: 1112 EALQRRPDDINTRAADMWSFAILMWELETREV-PFAELSSMEVGMKVALEGLRISIPPGI 936
Query: 494 PPTLYSLMTKCWAYDPSRRPRF 515
+ L+ C +P +RPRF
Sbjct: 935 SLHMSRLIKICMNEEPGKRPRF 870
>13212
Length = 1067
Score = 61.6 bits (148), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 51/196 (26%), Positives = 84/196 (42%), Gaps = 18/196 (9%)
Frame = -1
Query: 341 VWIIMELCTL---GELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARN 397
VW I+++ + G L S + + + A + +++ AL +L +HRDI A N
Sbjct: 1067 VWXIVDVFRVLWWGALDSIMVDLEKPMTEAQICYVCHEMCMALDFLHRHHVIHRDIKAGN 888
Query: 398 VLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAP-----ESINFRRFTSASDVW 452
VL++ + VKL DFG+S + + + P WMAP E++ + +D+W
Sbjct: 887 VLLTIDGEVKLADFGVSAKNTQTQQKRDTFIGTPY-WMAPEVVLCETLKDTPYDFKADIW 711
Query: 453 MFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTL----------YSLMT 502
GV + E P + + V+ +I + PPTL +
Sbjct: 710 SLGVTLIE-FAQIEPPNKEMHPMRVLIKIHKSD--------PPTLEKPKKWTKLFKDFIA 558
Query: 503 KCWAYDPSRRPRFTEL 518
KC DP+ RP EL
Sbjct: 557 KCLVKDPNLRPTAAEL 510
>19094
Length = 898
Score = 61.6 bits (148), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 34/114 (29%), Positives = 62/114 (54%), Gaps = 3/114 (2%)
Frame = +1
Query: 351 GELRSFLQVRKYSL---DLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVK 407
G + +++R +L ++A+++ Y + L YL S+R +HRDI A N+L+++ K
Sbjct: 10 GSVSDIMRLRNKTLVEREIATILYYTLK---GL*YLHSRRKIHRDIKAGNILLNNEGHAK 180
Query: 408 LGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEI 461
L DFG++ + D+ + + P WMAPE I + +D+W G+ E+
Sbjct: 181 LADFGVAGQLTDTMAKRNTVIGTP-YWMAPEVIQEIGYDCVADIWSLGITALEM 339
>29581
Length = 1278
Score = 58.9 bits (141), Expect = 9e-09, Method: Compositional matrix adjust.
Identities = 43/147 (29%), Positives = 71/147 (48%), Gaps = 8/147 (5%)
Frame = -2
Query: 326 HPHIVKLIGVI---TENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAY 382
H +IV+L V+ + + ++++ME C +L S L + + QL L Y
Sbjct: 1178 HQNIVQLQEVVVGKSLDSLFLVMEYCE-QDLASLLDNMPAPFSESQVKCIVLQLLKGLRY 1002
Query: 383 LESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLP----IKWMAPE 438
L +HRD+ N+L++ CVK+ DFGL+R Y K K P + + APE
Sbjct: 1001 LHEAFIIHRDLKVSNLLMTDKGCVKIADFGLAR-----NYGKPQKPMTPKVVTLWYRAPE 837
Query: 439 SI-NFRRFTSASDVWMFGVCMWEILMH 464
+ + ++A D+W G + E+L H
Sbjct: 836 LLFGSKTHSTAIDMWSAGCILGELLGH 756
>19761
Length = 473
Score = 58.5 bits (140), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 34/130 (26%), Positives = 67/130 (51%), Gaps = 8/130 (6%)
Frame = -3
Query: 369 LILYAYQLSTALAYLESKR--FVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKAS 426
++ + Q ++AL Y+ + +HRD+ +N+ V+ V+LGD GL+R + + S
Sbjct: 417 IVCWLMQTASALNYMHTHTPVILHRDLKPQNIYVTEKGDVRLGDLGLARKLTGPADFATS 238
Query: 427 KGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIG------R 480
+ I +++PE ++ + + S SD+W G ++I G K +D +G +
Sbjct: 237 QVG-TIMYLSPEILSQQPYNSKSDIWSLGCVFYDI--------TGKKGSDEMGVMFLLVQ 85
Query: 481 IENGERLPMP 490
+ G +LP+P
Sbjct: 84 VMGGRKLPLP 55
>14126
Length = 1265
Score = 57.8 bits (138), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 48/185 (25%), Positives = 87/185 (47%), Gaps = 14/185 (7%)
Frame = +3
Query: 321 MRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVRKYSLDLASLIL--------- 371
+ Q++HP++V+L+ V + N + T E+R L DLA+ +
Sbjct: 360 LEQYEHPNVVRLLDV-SHNTI-------TDREIRLNLVFEYIEHDLATYLAKCPSPGLGP 515
Query: 372 -----YAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKAS 426
QL + +L S R VHRD+ +N+L+S + +KL DFGL+R S + +
Sbjct: 516 DRIKDLMLQLLNGVDFLHSNRIVHRDLKPQNLLISKDGRLKLADFGLARIY--SFHMALT 689
Query: 427 KGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGER 486
+ + + +PE + + ++ D+W G C++ L F+G D + +I E
Sbjct: 690 TVVVTLWYRSPEVLMQAEYGTSVDIWSCG-CIFAELFTRRALFKGSSEFDQLKKI--FEV 860
Query: 487 LPMPP 491
+ +PP
Sbjct: 861 IGLPP 875
>21079
Length = 878
Score = 56.6 bits (135), Expect = 4e-08, Method: Compositional matrix adjust.
Identities = 34/128 (26%), Positives = 66/128 (51%), Gaps = 2/128 (1%)
Frame = +1
Query: 343 IIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSS 402
++ME GEL + + L + + Q+ + + Y+ ++ +H D+ NVL S
Sbjct: 55 LVMEFVGAGELFERVIRDDFVLTERDCVHFVRQICSGVGYMHTQSILHLDLKPENVLCVS 234
Query: 403 NDC--VKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWE 460
++ +K+ DFGL+R+ + + G P +++APE +N+ +D+W GV +
Sbjct: 235 DNSNQIKIIDFGLARFYKPGDSLQVLFGT-P-EFIAPEVVNYDEINFTTDMWSIGVICY- 405
Query: 461 ILMHGVKP 468
IL+ G+ P
Sbjct: 406 ILLSGLSP 429
>04591
Length = 1117
Score = 56.6 bits (135), Expect = 4e-08, Method: Compositional matrix adjust.
Identities = 41/152 (26%), Positives = 69/152 (45%), Gaps = 11/152 (7%)
Frame = -2
Query: 321 MRQFDHPHIVKLIGVI---------TENPVWIIMELCTLGELRSFLQVRKYSLDLASLIL 371
++Q +H ++V+L + ++ ++I E C +L L + LA
Sbjct: 1059 LQQLEHENVVQLQEICHTQAGPYNRYKSTFYLIFEYCDY-DLAGLLNNLRVKFSLADKKN 883
Query: 372 YAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLP 431
QL L Y+ +K+ +HRDI A N+L++ + +KL DFGLSR S K ++
Sbjct: 882 LMSQLLNGLFYIHTKQILHRDIKAANILLTRDGVLKLADFGLSRPWVKS---KRLTNRVV 712
Query: 432 IKWMAPESINF--RRFTSASDVWMFGVCMWEI 461
W P + R + D+W G M E+
Sbjct: 711 TLWYRPPELLLGEREYGPEIDMWGVGCIMAEM 616
>01060
Length = 1800
Score = 55.5 bits (132), Expect = 9e-08, Method: Compositional matrix adjust.
Identities = 37/148 (25%), Positives = 78/148 (52%), Gaps = 5/148 (3%)
Frame = +1
Query: 321 MRQFDHPHIVKLIGVITENP-VWIIMELCTLGELRSFLQV--RKYSLDLASLILYAYQLS 377
+R+ H +IV L VI E+ ++++ E ++ +L+ ++ LD + Y +Q+
Sbjct: 232 LRELRHTNIVCLEDVIMEDERLFLVFEFLSM-DLKMYIDKFPEGVVLDRRLVKSYVFQIV 408
Query: 378 TALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWM-A 436
T + + +R VHRD+ +N+L++ +K+ DFG++R + +A ++ W A
Sbjct: 409 TGIXFCHQRRIVHRDLKPQNLLINHTGAIKIADFGMARTF--ALPVRAYTHEVVTLWYRA 582
Query: 437 PESI-NFRRFTSASDVWMFGVCMWEILM 463
PE + ++++ DVW G ++L+
Sbjct: 583 PEILMGASKYSTPVDVWSIGTIFADMLI 666
>18484
Length = 635
Score = 55.5 bits (132), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 28/113 (24%), Positives = 59/113 (52%)
Frame = +1
Query: 371 LYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKL 430
YA +++ L +L + ++RD+ NV++ S +K+ DFG+ + +
Sbjct: 55 FYAAEIAVGLFFLHDQGIIYRDLKLDNVMLDSEGHIKIADFGMCKEGMTGDATTRTFCGT 234
Query: 431 PIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIEN 483
P ++APE + ++ ++ + D W +GV ++E+L G PF G +++ I +
Sbjct: 235 P-DYIAPEIVLYQPYSKSVDWWAYGVLLFEMLA-GQPPFDGEDEDELFSSITD 387
>07836
Length = 1478
Score = 53.9 bits (128), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 56/215 (26%), Positives = 93/215 (43%), Gaps = 38/215 (17%)
Frame = -1
Query: 351 GELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRF--------VHRDIAARNVLVSS 402
G L +L R LD + ++ A+ LA+L + F HRDI ++N+LV
Sbjct: 1298 GSLHDYLLSR--VLDSSEMLALAHSAICGLAHLHIEIFGTRGKPAIAHRDIKSKNILVKK 1125
Query: 403 NDCVKLGDFGLS-RYMEDSTYYKASKG--KLPIKWMAPESI-------NFRRFTSASDVW 452
N + D GL+ RY+ +S + + ++MAPE + NF F A D++
Sbjct: 1124 NGTCCIADLGLAVRYISESNEVDVAPNPRQGTKRYMAPEVLEMLLNVKNFDAFKQA-DMY 948
Query: 453 MFGVCMWEI----LMHGVK-----PFQGVKNND--------VIGRIENGERLPMPPNCPP 495
FG+ MWEI ++ GV PF +D V+ + +P+ P
Sbjct: 947 AFGLVMWEIARCCVIGGVAEEYQVPFYNCLPHDPSFEDVRLVVSVDKVRPDIPLRWQEDP 768
Query: 496 ---TLYSLMTKCWAYDPSRRPRFTELKAQLSTILE 527
+ +M +CW+ +P+ R +K L + E
Sbjct: 767 IMKVMVKVMCECWSGNPAARLTALRVKKTLGKLSE 663
>03240
Length = 1683
Score = 53.5 bits (127), Expect = 4e-07, Method: Compositional matrix adjust.
Identities = 49/190 (25%), Positives = 80/190 (42%), Gaps = 45/190 (23%)
Frame = -3
Query: 325 DHPHIVKLIGVITE-NPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYL 383
D+ +VKL + N ++ +M+ G+L L +R LD Y +L A+ +
Sbjct: 1117 DNEWVVKLYYSFQDHNYLYFVMDYVPGGDLMGLL-IRMEILDEPLARFYVAELVQAIESV 941
Query: 384 ESKRFVHRDIAARNVLVSSNDCVKLGDFGLS---RYMEDSTYYK-----ASKGKLPIK-- 433
F+HRDI N+L+ N +KL DFGL R+ +S YY+ A + + +K
Sbjct: 940 HRMGFIHRDIKPDNILIDRNGHIKLTDFGLCTGFRWTHNSKYYQRDGTHARQDSMEVKCQ 761
Query: 434 ---------------------------------WMAPESIN-FRRFTSASDVWMFGVCMW 459
++APE ++ +TS D W GV ++
Sbjct: 760 LDEQCQCEILKPLERRRKREQRCLAHSLVGTPNYIAPEVLSRLGGYTSVCDWWSVGVILF 581
Query: 460 EILMHGVKPF 469
E+L+ G PF
Sbjct: 580 EMLV-GHPPF 554
>15910
Length = 1361
Score = 50.8 bits (120), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 34/110 (30%), Positives = 56/110 (50%), Gaps = 3/110 (2%)
Frame = +2
Query: 379 ALAYLESKRFVHRDIAARNVL---VSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWM 435
+ Y+ + VHRD+ N+L ++ + +KL DFGLSR +E G P +
Sbjct: 500 GVQYIHANGVVHRDLKPENLLYECMTDDSKLKLADFGLSRIIEPEVQMSTVCGT-P-GYC 673
Query: 436 APESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGE 485
APE + ++T + D+W GV + IL+ G +PF ++ +I GE
Sbjct: 674 APEVLKGDKYTPSVDMWSVGVIAY-ILLCGYEPFFAENEFEMYRKIIKGE 820
>01756
Length = 1858
Score = 50.8 bits (120), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 35/153 (22%), Positives = 68/153 (44%), Gaps = 12/153 (7%)
Frame = -3
Query: 321 MRQFDHPHIVKLIGVIT---------ENPVWIIMELCTLGELRSFLQVRKYSLDLASLIL 371
++ +H ++V LI + + ++ +++ E C +L L +L +
Sbjct: 1583 LQLLNHENVVDLIEICSTKATSANRYKSMFYLVFEFCE-HDLAGLLSNMSVVFNLPEIKE 1407
Query: 372 YAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSR-YMEDSTYYKASKGKL 430
QL L Y+ + +HRD+ A N+L++ +KL DFGL+R + + ++
Sbjct: 1406 VMKQLMNGLYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRV 1227
Query: 431 PIKWMAPESINF--RRFTSASDVWMFGVCMWEI 461
W P + R +++A D W G M E+
Sbjct: 1226 VTLWYRPPELLLGDRNYSTAIDQWGAGCIMAEM 1128
>26711
Length = 405
Score = 50.8 bits (120), Expect = 2e-06, Method: Composition-based stats.
Identities = 32/102 (31%), Positives = 58/102 (56%), Gaps = 5/102 (4%)
Frame = -2
Query: 375 QLSTALAYLESKRFVHRDIAARNVLVSSN--DCVKLGDFGLSRYM---EDSTYYKASKGK 429
Q+ L ++ ++ VH D+ N+L+S + D V+L DFGL+R + +++ + G
Sbjct: 392 QVLDILQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARKLYPPQETFLNHGTPG- 216
Query: 430 LPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQG 471
+ +PE+++ + ++ASDVW GV + IL+ G PFQ
Sbjct: 215 ----FTSPEALDVKPISTASDVWGVGVLAY-ILLSGQSPFQA 105
>01966
Length = 1735
Score = 50.4 bits (119), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 27/98 (27%), Positives = 56/98 (57%), Gaps = 3/98 (3%)
Frame = -1
Query: 321 MRQFDHPHIVKLIGVITENP-VWIIMELCTLGELRSFLQV--RKYSLDLASLILYAYQLS 377
+R+ H +IV L VI E+ ++++ E ++ +L+ ++ LD + Y +Q+
Sbjct: 1552 LRELRHTNIVCLEDVIMEDERLFLVFEFLSM-DLKMYIDKFPEGVVLDRRLVKSYVFQIV 1376
Query: 378 TALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSR 415
T + + +R VHRD+ +N+L++ +K+ DFG++R
Sbjct: 1375 TGINFCHQRRIVHRDLKPQNLLINHTGAIKIADFGMAR 1262
>25550
Length = 941
Score = 49.3 bits (116), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 25/76 (32%), Positives = 37/76 (48%), Gaps = 1/76 (1%)
Frame = +3
Query: 454 FGVC-MWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRR 512
G C +W++ + GV +V +E G R+ P P +Y LM KCW +DP R
Sbjct: 12 MGACDIWDVX------YPGVDLTEVYHLLERGYRMERPQGTPADVYILMLKCWQWDPKER 173
Query: 513 PRFTELKAQLSTILEE 528
P F E+ L + E+
Sbjct: 174 PTFKEIHYLLENMFEK 221
>12672
Length = 773
Score = 48.9 bits (115), Expect = 8e-06, Method: Compositional matrix adjust.
Identities = 38/162 (23%), Positives = 69/162 (42%), Gaps = 16/162 (9%)
Frame = +3
Query: 377 STALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGL---SRYMEDSTYYKASKGKLPIK 433
++ + YL VHRDI N+L+ S K+GDF + E T AS
Sbjct: 21 ASGIQYLNDNGHVHRDIKTANILLDSEYTAKVGDFATVVSAPSGEGKTVQNASVVIGTAA 200
Query: 434 WMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPF----QGVKNNDVIGRIENGERL-- 487
++APE+I+F ++ D + FGV + E++ V + ++ ++ +E E +
Sbjct: 201 YLAPEAIHF-DVSTKLDSYSFGVVLLEVITGLVAQDYSREERTLSSHIMENVEEPEEIHD 377
Query: 488 -------PMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQL 522
P LY + +C +RP +++ +L
Sbjct: 378 FVDQSAGTWPDGAVDKLYDISMRCLNLSKKQRPNVKDIRPEL 503
>32264
Length = 287
Score = 48.9 bits (115), Expect = 9e-06, Method: Compositional matrix adjust.
Identities = 21/48 (43%), Positives = 28/48 (58%)
Frame = +1
Query: 481 IENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEE 528
IE+G RL P P ++Y LM +CW Y P +RP F EL L I+ +
Sbjct: 1 IEDGYRLQQNPQTPDSVYKLMLRCWEYVPEKRPHFKELYTSLKDIVRK 144
>21433
Length = 590
Score = 48.1 bits (113), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 30/98 (30%), Positives = 49/98 (50%)
Frame = +2
Query: 372 YAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLP 431
Y YQLS+AL Y ++ +HRDI N+L+ +K+ DFG S + S + +
Sbjct: 182 YIYQLSSALEYCHYRKVIHRDIKPENLLLGLKGDLKIADFGWSVHAPSS---RRTTMCGT 352
Query: 432 IKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPF 469
+ ++ PE + + D+W GV +E L+ G P
Sbjct: 353 LDYLPPEMVEGKTHDENVDLWSLGVLCYEFLV-GTPPL 463
>01707
Length = 757
Score = 47.8 bits (112), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 44/165 (26%), Positives = 73/165 (44%), Gaps = 15/165 (9%)
Frame = +1
Query: 313 DPRNAEVTMR------QFDHPHIVKLIGVITENP----VWIIMELCTLGELRSFLQVRKY 362
DP ++ MR Q HP++V+LI V V+ ++ L EL + R
Sbjct: 181 DPLIKKIAMREIRMLKQLKHPNLVRLIEVFRRKKRLHLVFDYVDHTLLNELDRY--PRGL 354
Query: 363 SLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYM----E 418
+ I+Y Q A+ + +HRD+ N+L++ VKL DFG +R + +
Sbjct: 355 PEPMVKRIIY--QTLLAVNFCHQYNTIHRDVKPENILITRQGQVKLCDFGFARILTGPGD 528
Query: 419 DSTYYKASKGKLPIKWMAPE-SINFRRFTSASDVWMFGVCMWEIL 462
+ T Y A++ + APE + ++ DVW G E+L
Sbjct: 529 EYTDYVATRW-----YRAPELLVGDTQYGPPVDVWAIGCVFAELL 648
>26560
Length = 398
Score = 44.3 bits (103), Expect = 2e-04, Method: Composition-based stats.
Identities = 34/113 (30%), Positives = 59/113 (52%), Gaps = 1/113 (0%)
Frame = -1
Query: 371 LYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKL 430
YA ++ L ++ S+ V+RD+ N+L+ N V++ D GL+ + AS G
Sbjct: 344 FYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGLACDFSKKRPH-ASVGTH 168
Query: 431 PIKWMAPESI-NFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIE 482
+MAPE + + + S++D + FG CM L+ G PF+ ++N RI+
Sbjct: 167 --GYMAPEVLMKGQSYDSSADWFSFG-CMLYKLLKGHSPFR--QHNQGQARID 24
>04138
Length = 800
Score = 43.5 bits (101), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 24/85 (28%), Positives = 42/85 (49%), Gaps = 3/85 (3%)
Frame = +1
Query: 380 LAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSR-YMEDSTYYKASKGKLPIKWMAPE 438
L Y+ + +HRD+ A N+L++ +KL DFGL+R + + ++ W P
Sbjct: 52 LYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRPP 231
Query: 439 SINF--RRFTSASDVWMFGVCMWEI 461
+ R +++A D W G M E+
Sbjct: 232 ELLLGDRNYSTAIDQWGAGCIMAEM 306
>01392
Length = 1806
Score = 42.4 bits (98), Expect = 8e-04, Method: Compositional matrix adjust.
Identities = 37/123 (30%), Positives = 59/123 (47%), Gaps = 12/123 (9%)
Frame = -1
Query: 367 ASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSND---CVKLGDFGLSRYME-DSTY 422
ASL++ ++ AL +L SK HRD+ N+L D VK+ DF L+ + D
Sbjct: 1785 ASLVVR--HIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGISCDGDG 1612
Query: 423 YKASKGKLPI---KWMAPESINFRRFTSAS-----DVWMFGVCMWEILMHGVKPFQGVKN 474
K + P+ ++MAPE ++ S S D+W G+ ++ I++ G PF G
Sbjct: 1611 TKTPELLTPVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILY-IMLCGYPPFYGQCG 1435
Query: 475 NDV 477
D
Sbjct: 1434 EDC 1426
>12786
Length = 460
Score = 40.8 bits (94), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 39/143 (27%), Positives = 69/143 (48%), Gaps = 23/143 (16%)
Frame = -3
Query: 363 SLDLASLILYAYQLSTALAYLESKRFVHRDIAARN-VLVSSNDCVKLGDFGLSRYMED-- 419
LD + Y ++ A+ L ++ +H D+ N +LV+ N +KL DFG++ ++
Sbjct: 422 GLDRMMIKFYWREMLRAVKALHNEGVIHSDLKPANFMLVAGN--LKLIDFGIANTLQQDK 249
Query: 420 STYYKASKGKLPIKWMAPESINFRRFTSA--------------------SDVWMFGVCMW 459
++ K S+ P +M+PE+I SA SDVW G C+
Sbjct: 248 TSVLKDSRVGTP-SYMSPEAIMAACDDSADDSMEEDGHRTKPKYKVGVRSDVWSLG-CIL 75
Query: 460 EILMHGVKPFQGVKNNDVIGRIE 482
+++G PFQ +KNN +G+++
Sbjct: 74 YNMVYGRTPFQHIKNN--MGKLQ 12
>07933
Length = 728
Score = 40.0 bits (92), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 15/39 (38%), Positives = 26/39 (66%)
Frame = +3
Query: 490 PPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEE 528
P CP LY++M +CW+ +PS RP F +L+ + ++E+
Sbjct: 3 PNYCPNLLYNIMMQCWSAEPSARPTFHKLEQDIVAMVEQ 119
>03508
Length = 1463
Score = 40.0 bits (92), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 26/100 (26%), Positives = 48/100 (48%), Gaps = 2/100 (2%)
Frame = +1
Query: 371 LYAYQLSTALAYLESKRFVHRDIAARNVLVS-SNDCVKLGDFGLSRYMEDSTYYKASKGK 429
Y Y+L AL + S +HRD+ NV++ N ++L D+GL+ + Y
Sbjct: 883 FYLYELMKALDFCHSMGIMHRDVKPHNVMIDHENKKLRLIDWGLAEFYHPGMEYNVRVAS 1062
Query: 430 LPIKWMAPE-SINFRRFTSASDVWMFGVCMWEILMHGVKP 468
K PE ++++ + + D+W G CM+ ++ +P
Sbjct: 1063RYFK--GPELLLDYQMYDYSLDMWSLG-CMFASMIFRKEP 1173
>28157
Length = 400
Score = 38.9 bits (89), Expect = 0.008, Method: Compositional matrix adjust.
Identities = 27/98 (27%), Positives = 46/98 (46%), Gaps = 6/98 (6%)
Frame = +3
Query: 321 MRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVR--KYSLDLASLILYAYQLST 378
+ + HP+IV L G ++PV ++ME G L + L + A + + Q +
Sbjct: 72 LSRVSHPNIVCLYGACRDHPVCLVMEYAEGGSLYNVLHGSGPQPQYTAAHAMNWLLQCAL 251
Query: 379 ALAYLES---KRFVHRDIAARN-VLVSSNDCVKLGDFG 412
+ YL K +HRD+ N +L+ +K+ DFG
Sbjct: 252 GVEYLHGMKPKALIHRDLKPPNLLLIQCGTKLKICDFG 365
>37602
Length = 804
Score = 38.5 bits (88), Expect = 0.011, Method: Compositional matrix adjust.
Identities = 22/71 (30%), Positives = 32/71 (45%)
Frame = -1
Query: 341 VWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLV 400
+WI ME C G ++ V L + + L YL + +HRDI N+L+
Sbjct: 294 LWIAMEYCGGGSMQDIYHVTG-PLTEPQIAFVCRETLKGLHYLHRRGKMHRDIKGANILL 118
Query: 401 SSNDCVKLGDF 411
+ VKL DF
Sbjct: 117 TEEGDVKLADF 85
>38046
Length = 446
Score = 38.1 bits (87), Expect = 0.015, Method: Composition-based stats.
Identities = 14/32 (43%), Positives = 24/32 (75%)
Frame = -1
Query: 376 LSTALAYLESKRFVHRDIAARNVLVSSNDCVK 407
++ A+AY+E + F+HR++ RN+LV N+ VK
Sbjct: 98 IADAMAYMEKENFIHRNLGDRNILVGPNNRVK 3
>18481
Length = 437
Score = 37.7 bits (86), Expect = 0.018, Method: Composition-based stats.
Identities = 26/82 (31%), Positives = 44/82 (53%), Gaps = 4/82 (4%)
Frame = -1
Query: 343 IIMELCTLG-ELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVS 401
++MEL LG L + K L ++++ + QL + L ++ K F+HRD+ N L+
Sbjct: 266 LVMEL--LGPSLEELFVICKRRFTLKTILMVSDQLLSRLEFIHQKCFIHRDLKPDNFLMG 93
Query: 402 -SNDCVKLG--DFGLSRYMEDS 420
C +L DFGLS+ +D+
Sbjct: 92 LGRHCHRLYIIDFGLSKRYKDT 27
>11185
Length = 473
Score = 37.7 bits (86), Expect = 0.022, Method: Compositional matrix adjust.
Identities = 37/168 (22%), Positives = 62/168 (36%), Gaps = 21/168 (12%)
Frame = +1
Query: 372 YAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRY----MEDSTYYKASK 427
+ L T L Y+ S + D+ VL+ ++ +K DFGLS+ +E+ + A
Sbjct: 16 FGIHLVTGLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEA 195
Query: 428 G-------------KLPIK----WMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQ 470
G ++P +MAPE + SD+W G +E+
Sbjct: 196 GDQWNIQSAEEMMKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMF-------- 351
Query: 471 GVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTEL 518
+G RL P+ P +L+ D +RR + L
Sbjct: 352 ------------SGSRLSAKPS--PEFLNLLESLLQKDSTRRLSWASL 453
>00486
Length = 797
Score = 35.0 bits (79), Expect = 0.12, Method: Compositional matrix adjust.
Identities = 24/81 (29%), Positives = 36/81 (44%)
Frame = -2
Query: 432 IKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPP 491
I++MAPE + A D W G M+++L G PF I +I G +L +PP
Sbjct: 766 IEYMAPEILTRTGHGKAVDWWSLGALMYDMLT-GSPPFTAENRKKTIDKILKG-KLNLPP 593
Query: 492 NCPPTLYSLMTKCWAYDPSRR 512
L+ K +P+ R
Sbjct: 592 YLTNEARGLIKKLLRKNPAER 530
>26009
Length = 886
Score = 34.7 bits (78), Expect = 0.17, Method: Compositional matrix adjust.
Identities = 15/30 (50%), Positives = 21/30 (70%)
Frame = +3
Query: 375 QLSTALAYLESKRFVHRDIAARNVLVSSND 404
QL +AL ++ SK+ VHRDI NVL+ + D
Sbjct: 735 QLVSALDFMHSKQLVHRDIKPENVLILTPD 824
>27287
Length = 514
Score = 33.9 bits (76), Expect = 0.26, Method: Compositional matrix adjust.
Identities = 13/37 (35%), Positives = 20/37 (54%)
Frame = -2
Query: 490 PPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTIL 526
PP ++ +M CW DP+ RP F+ L +L +L
Sbjct: 504 PPYASSEMFGIMHSCWQEDPNDRPSFSRLVQELDKML 394
>16708
Length = 1397
Score = 33.9 bits (76), Expect = 0.27, Method: Compositional matrix adjust.
Identities = 17/49 (34%), Positives = 27/49 (55%)
Frame = -1
Query: 367 ASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSR 415
A + A Q AL ++ VH D+ A NVLV ++ KL D+G+++
Sbjct: 1094 AMVCCIAGQXVCALEHIHELGVVHMDVKADNVLVDAHGNCKLTDYGIAQ 948
>15741
Length = 402
Score = 33.9 bits (76), Expect = 0.29, Method: Composition-based stats.
Identities = 15/44 (34%), Positives = 24/44 (54%)
Frame = -3
Query: 356 FLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVL 399
FL L +A ++ +A++ + + VHRD+AARNVL
Sbjct: 133 FLTSTANDLTARDFFSFALHVARGMAHVANNKIVHRDVAARNVL 2
>27405
Length = 532
Score = 33.9 bits (76), Expect = 0.30, Method: Compositional matrix adjust.
Identities = 14/44 (31%), Positives = 26/44 (59%)
Frame = -3
Query: 371 LYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLS 414
YA ++ L ++ S+ V+RD+ N+L+ N V++ D GL+
Sbjct: 242 FYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGLA 111
>02638
Length = 1490
Score = 33.5 bits (75), Expect = 0.35, Method: Compositional matrix adjust.
Identities = 28/92 (30%), Positives = 42/92 (45%), Gaps = 5/92 (5%)
Frame = +1
Query: 432 IKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKP---FQGVKNN-DVIGRIENG-ER 486
I +MAPE + + A DVW G M E M +P + N+ +I +I + +
Sbjct: 28 IAFMAPEVLRGESYGRACDVWSVGCVMIE--MCTCRPPWNSHDISNHLALIFKIASSVDP 201
Query: 487 LPMPPNCPPTLYSLMTKCWAYDPSRRPRFTEL 518
P+P N P + LM +C D RP +L
Sbjct: 202 PPIPENMSPPVRDLMLRCLEQDSDFRPSAKDL 297
>21210
Length = 518
Score = 33.5 bits (75), Expect = 0.39, Method: Compositional matrix adjust.
Identities = 30/104 (28%), Positives = 47/104 (45%), Gaps = 7/104 (6%)
Frame = +3
Query: 434 WMAPESINFRR----FTSASDVWMFGVCMWEILMHGVKPFQG-VKNNDVIGRIENGER-- 486
+MAPE I+ R + SDVW G+ + E L G P++ V D + ++ G
Sbjct: 18 YMAPERIDPRASSHGYDVRSDVWSLGITLME-LATGRFPYRKWVSIFDQLQQVVRGVAPC 194
Query: 487 LPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEK 530
LP + + KC D +RP++ +L A L EE+
Sbjct: 195 LPHDGAFSHDFVNFVNKCLTKDEKQRPKYNKLLAHPFVRLYEEQ 326
>25019
Length = 730
Score = 31.6 bits (70), Expect = 1.5, Method: Composition-based stats.
Identities = 22/62 (35%), Positives = 29/62 (46%)
Frame = +3
Query: 394 AARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWM 453
AA NVL+ + VKL DFGL + T + I++MAPE + A D W
Sbjct: 255 AAENVLLDKDGHVKLTDFGLCKEAITGTRVTHTFCG-TIEYMAPEILTRTGHGKAVDWWS 431
Query: 454 FG 455
G
Sbjct: 432 LG 437
>06601
Length = 737
Score = 29.6 bits (65), Expect = 5.5, Method: Composition-based stats.
Identities = 19/51 (37%), Positives = 24/51 (47%)
Frame = +1
Query: 30 LDSVKAKTLRKLIQQTFRQFANLNREESILKFFEILSPVYRFDKECFKCAL 80
L S K KT L+ T+ LNR K F++ V+RF K C C L
Sbjct: 139 LRSAKTKTCESLVVSTYFY---LNRNA---KHFQLGKSVFRFHKMCLICVL 273
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000378640 | hsapiens_gene_ensembl | Focal adhesion
kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK) (Protein- tyrosine kinase
2). [Source:Uniprot/SWISSPROT;Acc:Q05397]
(894 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
06405 207 2e-53
21808 185 8e-47
11780 109 4e-41
09007 161 1e-39
04852 155 9e-38
07291 137 1e-32
14116 131 1e-30
17300 124 4e-30
20640 125 7e-29
07940 119 7e-27
08294 117 2e-26
18996 111 1e-24
14477 95 1e-19
17637 90 4e-18
22005 87 2e-17
13305 87 3e-17
18921 86 5e-17
17253 84 4e-16
01718 80 4e-15
00300 78 1e-14
19301 75 1e-13
12721 74 2e-13
30755 69 6e-12
14420 69 6e-12
27546 69 6e-12
13592 67 3e-11
31885 67 4e-11
09606 64 3e-10
13066 64 4e-10
00715 62 9e-10
07833 62 1e-09
13212 62 1e-09
19094 61 2e-09
29581 59 1e-08
19761 59 1e-08
14126 58 1e-08
04591 57 4e-08
21079 56 5e-08
01060 55 1e-07
18484 55 1e-07
03240 54 3e-07
07836 54 4e-07
01756 51 2e-06
15910 51 3e-06
01966 50 3e-06
26711 50 3e-06
25550 49 6e-06
12672 49 8e-06
32264 49 9e-06
21433 48 2e-05
01707 47 2e-05
26560 44 2e-04
04138 44 4e-04
01392 42 0.001
12786 41 0.002
07933 40 0.004
03508 40 0.005
28157 39 0.009
37602 39 0.013
38046 38 0.015
18481 38 0.018
11185 37 0.024
00486 35 0.12
26009 35 0.17
16708 34 0.26
27287 34 0.28
15741 34 0.30
27405 34 0.30
02638 33 0.36
21210 33 0.37
25019 32 1.6
06601 30 5.6
>06405
Length = 1965
Score = 207 bits (527), Expect = 2e-53, Method: Compositional matrix adjust.
Identities = 109/303 (35%), Positives = 165/303 (54%), Gaps = 2/303 (0%)
Frame = +1
Query: 224 PSTRDYEIQRERIELGRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFL 283
P +EI+R I + +G GQ+GDV++ ++ VA+KT K T FL
Sbjct: 229 PEPDRWEIERTEIAMKHRLGGGQYGDVYEAMWKRYNK---IVAVKTLKEDTM--ALNDFL 393
Query: 284 QEACHYTSLHWNWCRYISDPNVDCPDPRNAEVTMRQFDHPHIVKLIGVIT-ENPVWIIME 342
+EA M++ HP++V+L+GV T E P +I+ E
Sbjct: 394 EEAA----------------------------IMKEMKHPNLVQLLGVCTREPPFYIVTE 489
Query: 343 LCTLGELRSFLQVRKYSLDLASLILY-AYQLSTALAYLESKRFVHRDIAARNVLVSSNDC 401
G L +L+ + + ++Y A Q+++ +AYLE+K F+HRD+AARN LV+ ++
Sbjct: 490 FMPHGNLLDYLRSSTREENGPTALMYMATQIASGMAYLETKNFIHRDLAARNCLVADSNM 669
Query: 402 VKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHG 461
VK+ DFGL+R M+D TY K PIKW APE + F RF++ SD+W FGV +WE+ +G
Sbjct: 670 VKVADFGLARLMKDDTYTAHIGAKFPIKWTAPEGLAFNRFSTRSDIWAFGVLLWELATYG 849
Query: 462 VKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTI 521
+ P+ GV+ +V +E G R+ PP P +Y LM KCW +DP RP F E+ L +
Sbjct: 850 MSPYPGVELTEVYHLLERGYRMERPPGTPADVYILMLKCWQWDPKDRPTFKEIHFLLENM 1029
Query: 522 LEE 524
E+
Sbjct: 1030FEK 1038
>21808
Length = 1011
Score = 185 bits (469), Expect = 8e-47, Method: Compositional matrix adjust.
Identities = 85/207 (41%), Positives = 129/207 (62%), Gaps = 1/207 (0%)
Frame = +1
Query: 317 MRQFDHPHIVKLIGVITEN-PVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTA 375
M++ HP +++L V T++ P++II EL G L FLQ + L L +LI Q++
Sbjct: 94 MKKLRHPKLIQLYAVCTQDDPIFIITELMKNGSLLEFLQGKGRVLKLPALIDIGAQIACG 273
Query: 376 LAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPES 435
+AYLES+ ++HRD+AARN+LVS N+ VK+ DFGL+R +++ Y + PIKW APE+
Sbjct: 274 MAYLESQNYIHRDLAARNILVSDNNTVKIADFGLARVIKEDEYEARVGARFPIKWTAPEA 453
Query: 436 INFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYS 495
N+ RFT SDVW FG+ + E + +G P+ G+ N +V+ ++E+G R+P PP CP LY
Sbjct: 454 ANYNRFTIKSDVWSFGILLTETVTYGRVPYPGMTNAEVLHQVEHGYRMPCPPGCPKPLYD 633
Query: 496 LMTKCWAYDPSRRPRFTELKAQLSTIL 522
+M +CW + RP + IL
Sbjct: 634 IMLECWRKEEMERPHLRNPAMEAGGIL 714
>11780
Length = 1713
Score = 109 bits (273), Expect(2) = 4e-41, Method: Compositional matrix adjust.
Identities = 71/207 (34%), Positives = 104/207 (50%), Gaps = 1/207 (0%)
Frame = +3
Query: 231 IQRERIELGRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEACHYT 290
I + +E+G IG+G FGDV++G+Y VAIK K+ D + FLQEA T
Sbjct: 588 IAXQDLEIGEAIGKGDFGDVYKGMYRGQ-----PVAIKQLKD--KDRGEQSFLQEASVMT 746
Query: 291 SLHWNWCRYISDPNVDCPDPRNAEVTMRQFDHPHIVKLIGVITENPVWIIMELCTLGELR 350
SL H ++V+LIGV+ ++++ E G L
Sbjct: 747 SLR----------------------------HDNLVRLIGVVLGETIFLVTEFMGKGNLV 842
Query: 351 SFLQVRKYS-LDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGL 409
+L+ R S + I +A A+ YLESKR VHRD+AARNVLV + K+ DFGL
Sbjct: 843 EYLRSRGRSVITKKDQINFATDTCAAMEYLESKRLVHRDLAARNVLVHDDGKAKVSDFGL 1022
Query: 410 SRYMEDSTYYKASKGKLPIKWMAPESI 436
+++ + + + K PIKW APE++
Sbjct: 1023AKFGD----FSQTSVKFPIKWTAPEAL 1091
Score = 77.8 bits (190), Expect(2) = 4e-41, Method: Compositional matrix adjust.
Identities = 33/81 (40%), Positives = 49/81 (60%)
Frame = +1
Query: 440 RFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTK 499
+FTS SD+W FG+ +WEI G P+ + DV+ +E G R+ P CPP +YS+M +
Sbjct: 1102 KFTSKSDMWSFGILLWEIYSFGRVPYPRIPLTDVVMHVERGYRMEAPEGCPPEIYSIMKQ 1281
Query: 500 CWAYDPSRRPRFTELKAQLST 520
W DP+ RP F + A+L+
Sbjct: 1282 AWELDPNERPTFKSVLARLNN 1344
>09007
Length = 1440
Score = 161 bits (407), Expect = 1e-39, Method: Compositional matrix adjust.
Identities = 97/302 (32%), Positives = 148/302 (49%), Gaps = 11/302 (3%)
Frame = -1
Query: 231 IQRERIELGRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEACHYT 290
I ++ + L + +G+G FG V Q I+ + + VA+K C S K QE T
Sbjct: 888 ISKDCVALSKSLGQGHFGTVRQAIWTAESGEKVQVAVK----CLSKDKIHKDGQEFLKET 721
Query: 291 SLHWNWCRYISDPNVDCPDPRNAEVTMRQFDHPHIVKLIGVITENPVWIIMELCTLGELR 350
++ M+ DH +IV++ GV+ +N IM + L +R
Sbjct: 720 AI------------------------MQMLDHENIVRVYGVVMDNGA-DIMLVTELAPMR 616
Query: 351 SFLQVRK-----YSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLG 405
S L+ K + L ++ Q+ ++YLESKR VHRD+AARN+L+ S VK+
Sbjct: 615 SLLECVKEVSARVDFSVPRLCDFSQQVCDGMSYLESKRLVHRDLAARNILLFSKSKVKIS 436
Query: 406 DFGLSRYMEDSTYYKASKGKL----PIKWMAPESINFRRFTSASDVWMFGVCMWEILMHG 461
D G+S + Y S+ + + W APES F+SASDVW FGV +WE HG
Sbjct: 435 DVGVSGALGAGKEYYQSQQTIHLQNAVAWCAPESFRNLCFSSASDVWAFGVLLWEFFTHG 256
Query: 462 VKPFQGVKNNDVIGRIE--NGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLS 519
+P+ G+ ++ ++ +RL P CP Y++M KCW +P RRP F++L L
Sbjct: 255 FQPWAGLNGQQIMEAVDAPQSQRLEQPDLCPKEYYAVMLKCWEQEPQRRPTFSQLFLTLP 76
Query: 520 TI 521
I
Sbjct: 75 QI 70
>04852
Length = 1462
Score = 155 bits (391), Expect = 9e-38, Method: Compositional matrix adjust.
Identities = 80/227 (35%), Positives = 126/227 (55%), Gaps = 26/227 (11%)
Frame = +1
Query: 322 HPHIVKLIGVITEN-PVWIIMELCTLGELRSFLQ-----VRKYS---------------- 359
H +IV +G T+ P+W+I+E G LR FL+ + Y
Sbjct: 127 HINIVNFLGCCTQGGPLWVIVEFAKNGNLRDFLESCRDGINGYGKFVSPQDPGWYTKTPG 306
Query: 360 ---LDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDS 416
+ +L+ YA+Q++ + +L S++ +HRD+AARNVLV+ +K+ DFGLSR
Sbjct: 307 GHVIRRKNLLSYAFQIARGMEFLASRKCIHRDLAARNVLVTEEHVLKIADFGLSR--TGD 480
Query: 417 TYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGR 476
Y K S G+LP+KWMAPE++ R+T+ SDVW FGV +WEI G P+ + N ++ +
Sbjct: 481 YYKKRSGGRLPVKWMAPEALFDMRYTTKSDVWSFGVVLWEIFSLGGMPYASIPNEELYSK 660
Query: 477 -IENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTIL 522
+++ R+P P LY++M +CW PS RP F++L + +L
Sbjct: 661 LLDDAYRMPRPELASGNLYAIMERCWLNRPSDRPEFSQLVGHIDRLL 801
>07291
Length = 833
Score = 137 bits (346), Expect = 1e-32, Method: Compositional matrix adjust.
Identities = 62/164 (37%), Positives = 101/164 (61%), Gaps = 2/164 (1%)
Frame = +1
Query: 360 LDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYY 419
L + L+ + Q++ +AYL+ + VHR++AARN +V+ + ++L D+G++ + +YY
Sbjct: 40 LTVVQLLDFGRQIADGMAYLQEVKVVHRNLAARNCIVTEDGRLQLSDYGVTGSLFPQSYY 219
Query: 420 KA--SKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRI 477
A S + +KWMAPE+I+ F+S SDVW FGV +WE+L G+ P+ V+N+ ++ +
Sbjct: 220 TADDSPARDLVKWMAPETIDNFHFSSKSDVWAFGVVLWELLTRGITPYPDVENSSLLPYL 399
Query: 478 ENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTI 521
+ G R+ P P +Y +MT CW P +RP F EL QL T
Sbjct: 400 KEGHRMKKPKQSPEPVYEMMTACWNESPEQRPDFAELNDQLKTF 531
>14116
Length = 1017
Score = 131 bits (329), Expect = 1e-30, Method: Compositional matrix adjust.
Identities = 84/287 (29%), Positives = 140/287 (48%), Gaps = 19/287 (6%)
Frame = -1
Query: 194 EKQGMRTHAVSVSETDDYAEIID------------EEDTYTMPSTRDYEIQRERIELGRC 241
+ G RT+ + E +DY +D +ED + I RE + +G
Sbjct: 789 DSNGTRTYNLEARE-NDYFNRLDVQGAEAMPLLHIDEDMMKLIENESLLIDREFLTMGEE 613
Query: 242 IGEGQFGDVHQGIYMSPENPA-LAVAIKTCKNCTSDSVR-EKFLQEACHYTSLHWNWCRY 299
IG+G FG V +G PE + VA+KT N + + FLQEA
Sbjct: 612 IGKGNFGCVKRGFLTLPEQKGDILVAVKTLHNNNPREIELQSFLQEA------------- 472
Query: 300 ISDPNVDCPDPRNAEVTMRQFDHPHIVKLIGV---ITENPVWIIMELCTLGELRSFLQVR 356
+ M+ F H +++ LIG+ + + P+ +++ G+L ++++
Sbjct: 471 ---------------LIMKDFHHSNVLTLIGICLNLDDMPL-VVLPFMKHGDLLTYIRDD 340
Query: 357 KYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDS 416
++ + LI+Y ++ + YL +FVHRD+AARN ++ + VK+ DFGL+R + +
Sbjct: 339 QHQPTIKDLIMYGVDIARGMDYLAGLKFVHRDLAARNCMLDEDFHVKVADFGLARDIYEK 160
Query: 417 TYYKA--SKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHG 461
YY + K KLP+KWMA ES+ + S +DVW +GV +WE+L G
Sbjct: 159 EYYSSENKKAKLPVKWMALESLEKGNYDSKTDVWSYGVVLWELLTRG 19
>17300
Length = 480
Score = 124 bits (310), Expect(2) = 4e-30, Method: Compositional matrix adjust.
Identities = 56/117 (47%), Positives = 78/117 (66%), Gaps = 3/117 (2%)
Frame = +1
Query: 372 LSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTY---YKASKGKLPI 428
+S+ + L +VHRD+AARN+LV+ K+ DFGLSR +E T Y GK+P+
Sbjct: 1 ISSGMGXLADMGYVHRDLAARNILVNEILVCKVADFGLSREIESDTTEGAYTTKGGKIPV 180
Query: 429 KWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPM 485
+W APE+I +R+FTSASDVW FGV MWE++ +G +P+ N DVI +E G RLP+
Sbjct: 181 RWTAPEAIAYRKFTSASDVWSFGVVMWEVMSYGERPYWNWSNQDVIKAVEKGYRLPL 351
Score = 26.9 bits (58), Expect(2) = 4e-30, Method: Compositional matrix adjust.
Identities = 10/35 (28%), Positives = 18/35 (51%)
Frame = +2
Query: 488 NCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTIL 522
+CP L+ LM W + S RP+ + + L ++
Sbjct: 356 DCPEALHQLMLDAWQKERSHRPKMSMVVKTLDKLI 460
>20640
Length = 1492
Score = 125 bits (314), Expect = 7e-29, Method: Compositional matrix adjust.
Identities = 55/139 (39%), Positives = 85/139 (61%), Gaps = 1/139 (0%)
Frame = +1
Query: 384 FVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASK-GKLPIKWMAPESINFRRFT 442
+VHRD+A RN LV + VK+ DFGL+R + YY+ S+ +PI+WM E+I + +F+
Sbjct: 7 YVHRDLATRNCLVGHDLVVKISDFGLARSVHSVDYYRGSEHDAIPIRWMPLEAILYNKFS 186
Query: 443 SASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWA 502
+ SDVW FGV +WEI ++P+ G+ + +V+ ++ G+ L P PP +Y LM +CW
Sbjct: 187 TQSDVWSFGVVLWEIFAFALQPYYGLTHEEVVRFVKEGKVLACPERTPPPMYELMKQCWH 366
Query: 503 YDPSRRPRFTELKAQLSTI 521
P+ RP F L L +
Sbjct: 367 RRPATRPSFHTLHKTLENM 423
>07940
Length = 1336
Score = 119 bits (297), Expect = 7e-27, Method: Compositional matrix adjust.
Identities = 54/111 (48%), Positives = 77/111 (69%), Gaps = 1/111 (0%)
Frame = -3
Query: 365 LILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYY-KASK 423
LI YAYQ++ + YL SK+ +HRD+AARNVLV+ +K+ DFGL+R ++ YY K +
Sbjct: 341 LISYAYQVARGMEYLASKQCIHRDLAARNVLVAEEYVLKIADFGLTRNLQQFDYYRKTTD 162
Query: 424 GKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVI 474
G+LP+KWMAPE++ R++TS SDVW +GV +WEI G P+ V D+
Sbjct: 161 GRLPVKWMAPEALFDRKYTSKSDVWSYGVLLWEIFTLGGNPYPSVPVEDLF 9
Score = 46.2 bits (108), Expect = 5e-05, Method: Compositional matrix adjust.
Identities = 37/141 (26%), Positives = 59/141 (41%), Gaps = 3/141 (2%)
Frame = -3
Query: 217 EEDTYTMPSTRDYEIQRERIELGRCIGEGQFGDVHQGIYMS--PENPALAVAIKTCKNCT 274
E Y +P +E RER+ LG +GEG FG V +G M +N ++ VA+K K
Sbjct: 893 EVSEYDLPLDAKWEFPRERLVLGDRLGEGAFGLVMKGEAMGIFKDNNSVTVAVKMLKEDA 714
Query: 275 SDSVREKFLQEACHYTSLHWNWCRYISDPNVDCPDPRNAEVTMRQFDHPHIVKLIGVITE 334
+D ++E E+ H +I+ L+G T+
Sbjct: 713 TDREMMDLIRE---------------------------MEMMKVIGKHKNIINLLGCCTQ 615
Query: 335 -NPVWIIMELCTLGELRSFLQ 354
+++I+E G LR FL+
Sbjct: 614 RGALYVIVEFAPHGNLRDFLK 552
>08294
Length = 1849
Score = 117 bits (293), Expect = 2e-26, Method: Compositional matrix adjust.
Identities = 67/209 (32%), Positives = 113/209 (54%), Gaps = 12/209 (5%)
Frame = +2
Query: 323 PHIVKLIGVITE-NPVWIIMELCTLGELRSFL-----------QVRKYSLDLASLILYAY 370
P+IV +GV E P ++I E C G+L+ FL R +L L+ +
Sbjct: 887 PNIVHFMGVCREAEPHFLITEYCDWGDLKQFLLATRNDNGRGRGTRVPALALSQKLGMGQ 1066
Query: 371 QLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKW 430
Q++ + L ++ VH D+AARNVL++S +K+ LS + S YY + +P++W
Sbjct: 1067 QVAAGMEALSNQGLVHGDLAARNVLLTSRMQLKVARPALSGDVYASEYYPLHQRLVPLRW 1246
Query: 431 MAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCP 490
+ PE + T+ DVW FGV +WE+L P++ + + +V+ +++ + P+ P
Sbjct: 1247 LPPEGVLEDSATTCGDVWAFGVFLWEVLQLADLPYRLMSDEEVLRSLQHSQAALDSPDAP 1426
Query: 491 PTLYSLMTKCWAYDPSRRPRFTELKAQLS 519
P L SL+ +C A PS+RP F+E+ + LS
Sbjct: 1427 PALLSLLQRCTAQQPSQRPPFSEICSVLS 1513
>18996
Length = 491
Score = 111 bits (277), Expect = 1e-24, Method: Compositional matrix adjust.
Identities = 56/136 (41%), Positives = 82/136 (60%), Gaps = 6/136 (4%)
Frame = +2
Query: 385 VHRDIAARNVLVSSNDCVKLGDFGLSRYME-DSTYYKASKGKLPIKWMAPESINFRRFTS 443
+HRD+AARN+LV + CVK+ DFGL+++ D YY S+ +PIKW +PE+I +F+S
Sbjct: 2 IHRDLAARNILVDRS-CVKISDFGLAQFANADGYYYGISQRDIPIKWYSPEAIETCKFSS 178
Query: 444 ASDVWMFGVCMWEILMHG----VKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYS-LMT 498
SDVW +GV ++E+ G + P + + + R+ GERLP P C +YS LM
Sbjct: 179 YSDVWSYGVTLFEMFSRGEIPNLLPGHDLTQEEFLNRLRKGERLPKPELCSDFVYSELMR 358
Query: 499 KCWAYDPSRRPRFTEL 514
CW P RP F ++
Sbjct: 359 PCWHEMPKSRPTFHQI 406
>14477
Length = 493
Score = 94.7 bits (234), Expect = 1e-19, Method: Compositional matrix adjust.
Identities = 63/196 (32%), Positives = 101/196 (51%), Gaps = 1/196 (0%)
Frame = -1
Query: 230 EIQRERIELGRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEACHY 289
+IQ + ++LG G FG V +G+ ++ + VAIK KN D
Sbjct: 490 QIQMDELKLG----AGNFGSVMKGVC-RLDDREIPVAIKVLKNADLD------------- 365
Query: 290 TSLHWNWCRYISDPNVDCPDPRNAEVTMRQFDHPHIVKLIGVITENPVWIIMELCTLGEL 349
P+V + AEV M++ DH HIV+LIG+ + +++EL LG L
Sbjct: 364 -------------PSVQSELIKEAEV-MKKMDHMHIVRLIGLCEGETMMLVLELAKLGPL 227
Query: 350 RSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGL 409
FL K+ L L +++ +Q+S + YLE+ +FVHRD+AARN+L+ K+ DFG+
Sbjct: 226 NKFLPKNKH-LPLWNILELMWQVSQGMEYLEANKFVHRDLAARNILLCDEHFAKISDFGM 50
Query: 410 SRYM-EDSTYYKASKG 424
S+ + ++ YY A +
Sbjct: 49 SKTLSRENNYYMAQEA 2
>17637
Length = 447
Score = 89.7 bits (221), Expect = 4e-18, Method: Compositional matrix adjust.
Identities = 46/128 (35%), Positives = 70/128 (54%), Gaps = 1/128 (0%)
Frame = +1
Query: 393 NVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKL-PIKWMAPESINFRRFTSASDVWMFG 451
N ++ VKL D LSR + Y G+ PIKW++ E++ + SDVW FG
Sbjct: 1 NCVIDDQLRVKLTDSALSRDLFSGDYNCLGDGEYRPIKWLSLEALQKSHYNEGSDVWSFG 180
Query: 452 VCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRF 511
V MWE+ G P+ + ++ +++G RL P NCP L+++M CWA P+ RP F
Sbjct: 181 VLMWEMCTLGKLPYAEIDPYEMEHYLKDGYRLAQPFNCPDELFTIMAYCWASMPAERPSF 360
Query: 512 TELKAQLS 519
++L+ LS
Sbjct: 361 SQLQICLS 384
>22005
Length = 873
Score = 87.4 bits (215), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 61/187 (32%), Positives = 93/187 (49%), Gaps = 45/187 (24%)
Frame = +1
Query: 317 MRQFDHPHIVKLIGVIT-ENPVWIIMELCTLGELRSFLQV---RKYSL------------ 360
M FDHP+IVKL+GV P+ ++ E + G+L FL++ Y+L
Sbjct: 172 MADFDHPNIVKLLGVCAIGKPMCLLFEFMSKGDLNDFLRLCSPENYNLPVSRSQNLVVDL 351
Query: 361 ----------------------DLASLI-----LY-AYQLSTALAYLESKRFVHRDIAAR 392
D + ++ LY + Q+S +AYL K +VHRD+A R
Sbjct: 352 EDGLRVEVEAEECEKDTQSEDRDCSGMLXTKDQLYISQQISAGMAYLAQKDYVHRDLATR 531
Query: 393 NVLVSSNDCVKLGDFGLSRYMEDSTYYKAS-KGKLPIKWMAPESINFRRFTSASDVWMFG 451
V + + DFGL+R + YY+ S + +PI+WM E+I + +F++ SDVW FG
Sbjct: 532 TVXSRTT*-S*ISDFGLARSVHSVDYYRGSEQDAIPIRWMPLEAILYSKFSTQSDVWSFG 708
Query: 452 VCMWEIL 458
V +WEIL
Sbjct: 709 VVLWEIL 729
>13305
Length = 549
Score = 87.0 bits (214), Expect = 3e-17, Method: Composition-based stats.
Identities = 37/100 (37%), Positives = 57/100 (57%)
Frame = +2
Query: 425 KLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLP 484
++PI+WMA ES+ +T+ SDVW FGV +WEI G P+ + +++G RL
Sbjct: 8 RVPIRWMAVESLFNNTYTTQSDVWSFGVVLWEIFTLGGTPYSSTDTQQLFAFLKDGYRLK 187
Query: 485 MPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEE 524
P C Y++M +CW + RRP F EL +L +L++
Sbjct: 188 RPKLCDQNTYAMMLQCWNENAQRRPTFPELCGRLQRMLDD 307
>18921
Length = 697
Score = 86.3 bits (212), Expect = 5e-17, Method: Compositional matrix adjust.
Identities = 56/181 (30%), Positives = 90/181 (49%), Gaps = 4/181 (2%)
Frame = +2
Query: 317 MRQFDHPHIVKLIGVITENP-VWIIMELCTLGELRSFLQVRKYSL---DLASLILYAYQL 372
M+Q D +IVK G +N +WI+ME C G + +++R +L ++A+++ Y +
Sbjct: 176 MQQCDSKYIVKYYGSYFKNTDLWIVMEYCGAGSVSDIMRLRNKTLVEREIATILYYTLK- 352
Query: 373 STALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMA 432
L YL S+R +HRDI A N+L+++ KL DFG++ + D+ + + P WMA
Sbjct: 353 --GLXYLHSRRKIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTPY-WMA 523
Query: 433 PESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPT 492
PE I + +D+W G+ E + G P I G+ P N PP
Sbjct: 524 PEVIQEIGYDCVADIWSLGITALE-MAEGKPPVMETS-------IL*GQSS*FPTNAPPP 679
Query: 493 L 493
L
Sbjct: 680 L 682
>17253
Length = 483
Score = 83.6 bits (205), Expect = 4e-16, Method: Composition-based stats.
Identities = 56/180 (31%), Positives = 88/180 (48%), Gaps = 14/180 (7%)
Frame = -1
Query: 265 VAIKTCKNCTSDSVREKFLQEACHYTSLHWNWCRYISDPNVDCPDPRNAEVTMRQFDHPH 324
VA+KT +D+ + +FL+E L PR HP+
Sbjct: 459 VAVKTHNEAATDAEKSEFLRELSIMRKL-----------------PR----------HPN 361
Query: 325 IVKLIGVIT-ENPVWIIMELCTLGELRSFLQVRK---------YSLDLASLILYAYQLST 374
+V +G T +P I+ME C G+L SFL+ R+ + DL + +++ L
Sbjct: 360 VVSFMGCCTMSDPALILMEFCCHGDLLSFLRKRRPDRTVFLTSTANDLTARDFFSFALHV 181
Query: 375 A--LAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDS--TYYKASKGKLPIKW 430
A +A++ + + VHRD+AARNVL+S + K+ DFGLSR + D Y S+ LP++W
Sbjct: 180 ARGMAHVANNKIVHRDVAARNVLISERNVCKVSDFGLSRRVGDQNDVYEIVSRRPLPLRW 1
>01718
Length = 959
Score = 79.7 bits (195), Expect = 4e-15, Method: Compositional matrix adjust.
Identities = 62/224 (27%), Positives = 94/224 (41%), Gaps = 14/224 (6%)
Frame = +3
Query: 317 MRQFDHPHIVKLIGV-ITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTA 375
+ + H +I++ +GV + E + + E G L L+ + L I L+
Sbjct: 294 LNRLQHANILRFMGVCVHEGQLHALTEYIPSGNLEQLLEKKDEELPWTQRIQLTLGLARG 473
Query: 376 LAYLESKRFVHRDIAARNVLVSSNDC----VKLGDFGLSRYMEDSTYYKASKGKLPI--- 428
L YL S RF+HRD+ ++N+L+ D + DFGL+ + D K KLP
Sbjct: 474 LDYLHSTRFIHRDLTSKNILIRREDNHGYHAVIADFGLATKIPDPL----DKEKLPTVGS 641
Query: 429 -KWMAPESINFRRFTSASDVWMFGVCMWEILMH-----GVKPFQGVKNNDVIGRIENGER 482
WMAPE +N + +D++ G+ M EI + P D + E
Sbjct: 642 PYWMAPEVLNGHFYNERADLFSVGIIMCEITARIPADPDIMPRMNNFGVDYVALSE---- 809
Query: 483 LPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEK 526
M CP L KC DP +RPR E+ L I + K
Sbjct: 810 --MISYCPLDYLQLAFKCCQVDPQKRPRGVEIIEWLEKIFKNLK 935
>00300
Length = 2318
Score = 78.2 bits (191), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 74/302 (24%), Positives = 124/302 (41%), Gaps = 11/302 (3%)
Frame = -1
Query: 224 PSTRDYEIQRERIEL----GRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVR 279
P DY I R+ G IGEGQFG V+ + MS +A+K K +D +
Sbjct: 1700 PREPDYRINVRRVNFRWQRGNKIGEGQFGKVYTAVNMST---GELMALKEMKFQPNDLQQ 1530
Query: 280 EKFLQEACHYTSLHWNWCRYISDPNVDCPDPRNAEVTMRQFDHPHIVKLIGV-ITENPVW 338
L+E C + H ++VK GV + ++ +
Sbjct: 1529 ---LREMCDEIKI------------------------FEGIQHENLVKYYGVEVHKDEML 1431
Query: 339 IIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSS 398
+ ME C G + + K L + Y ++ A+ +L VHRDI N+ ++S
Sbjct: 1430 MFMEYCDTGTIE---EAAKMGLPEYLIRRYTREIVLAVNHLHENSIVHRDIKGANIFLTS 1260
Query: 399 NDCVKLGDFGLSRYMEDSTYYKASKGKL--PIKWMAPESINFRR---FTSASDVWMFGVC 453
N VKLGDFG S ++ T L +MAPE + A+D+W G
Sbjct: 1259 NGHVKLGDFGCSVKLKSHTTMPGEFHNLVGTTAYMAPEVFTQNDQGGYGRAADIWSLGCV 1080
Query: 454 MWEILMHGVKPFQGVKNN-DVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFT 512
+ E+ G +P+ + NN ++ ++ G + +P + + +DP++R +
Sbjct: 1079 VIEMAT-GKRPWHDLDNNYQIMYKVGIGHKPAVPDSLSVEGKHFLDLIMCHDPAQRALAS 903
Query: 513 EL 514
+L
Sbjct: 902 QL 897
>19301
Length = 712
Score = 75.1 bits (183), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 37/95 (38%), Positives = 61/95 (64%), Gaps = 1/95 (1%)
Frame = +2
Query: 317 MRQFDHPHIVKLIGVITENPVW-IIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTA 375
+R+ +HP+I+ GV T+ P + IIME C G+L L+ K + A ++ ++ Q+++
Sbjct: 431 LRKLNHPNIISFKGVCTQAPCYCIIMEYCPYGQLYEVLRDGK-EIPPALVLDWSKQIASG 607
Query: 376 LAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLS 410
+ YL S + +HRD+ + NVLV+ ND VK+ DFG S
Sbjct: 608 MNYLHSHKIIHRDLKSPNVLVAKNDVVKISDFGTS 712
>12721
Length = 821
Score = 74.3 bits (181), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 55/205 (26%), Positives = 88/205 (42%), Gaps = 8/205 (3%)
Frame = +1
Query: 312 NAEVTMRQFDHPHIVKLIG-VITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAY 370
N V MR + HP+IV++ + + +W++ME G L V +D +
Sbjct: 223 NEVVVMRDYHHPNIVEMYNSYLVNDELWVVMEFMEGGALTDI--VTNNRMDEVQIATVCR 396
Query: 371 QLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKW 430
ALA+L + +HRDI + ++L+S + VKL DFG + + S P W
Sbjct: 397 ACLKALAFLHANGVIHRDIKSDSILLSHDGKVKLXDFGFCAQVTQDLQKRKSLVGTPY-W 573
Query: 431 MAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPP--- 487
MAPE I+ + D+W G+ + E ++ PF + RI + MPP
Sbjct: 574 MAPEVISRLPYGPEVDIWSLGIMVME-MIDAEPPFFNEPPLQAMRRIRD-----MPPPKL 735
Query: 488 ----NCPPTLYSLMTKCWAYDPSRR 508
P L + + DP +R
Sbjct: 736 RNTHKISPRLQGFIDRMLVRDPHQR 810
>30755
Length = 1137
Score = 69.3 bits (168), Expect = 6e-12, Method: Compositional matrix adjust.
Identities = 44/143 (30%), Positives = 76/143 (53%), Gaps = 1/143 (0%)
Frame = +2
Query: 367 LYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKL 426
Y ++ +AL YL S+ ++RD+ N+L+ + +K+ DFGL + ED TY + +K
Sbjct: 44 FYGAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCK--EDITYGRTTKTFC 217
Query: 427 PI-KWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPM 485
+++APE ++ + A D W GV M+E++ G PF +++DV+ + E +
Sbjct: 218 GTPEYLAPEVLDDNDYGRAVDWWGTGVVMYEMIC-GRLPFYN-RDHDVLFTLILVEDVKF 391
Query: 486 PPNCPPTLYSLMTKCWAYDPSRR 508
P N SL++ A DP R
Sbjct: 392 PRNITDEAKSLLSGLLAKDPRNR 460
>14420
Length = 528
Score = 69.3 bits (168), Expect = 6e-12, Method: Compositional matrix adjust.
Identities = 42/155 (27%), Positives = 73/155 (47%), Gaps = 1/155 (0%)
Frame = +2
Query: 312 NAEVTMRQFDHPHIVK-LIGVITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAY 370
N + MR+ +P+IV L + +W++ME G L V + +D +
Sbjct: 47 NEILVMRENQNPNIVNYLDSYLVGEELWVVMEFLAGGSLTDV--VTETCMDEGQIAAVCR 220
Query: 371 QLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKW 430
+ AL +L + +HRDI + N+L+ + VKL DFG + +++ P W
Sbjct: 221 ECLQALEFLHENQVIHRDIKSDNILLGMDGSVKLTDFGFCAQLSPEQSKRSTMVGTP-YW 397
Query: 431 MAPESINFRRFTSASDVWMFGVCMWEILMHGVKPF 465
MAPE + +++ D+W GV E ++ G P+
Sbjct: 398 MAPEVVTRKQYGPTVDIWSLGVMCIE-MIEGEPPY 499
>27546
Length = 426
Score = 69.3 bits (168), Expect = 6e-12, Method: Composition-based stats.
Identities = 35/108 (32%), Positives = 61/108 (56%), Gaps = 1/108 (0%)
Frame = -1
Query: 310 PRNAEVTMRQFDHPHIVKLIGVITENP-VWIIMELCTLGELRSFLQVRKYSLDLASLILY 368
PR E+ R DHP+I+++ ++ P ++I M G++ S ++ + +D A ++
Sbjct: 336 PRELEILTR-LDHPNIIQIHSILQRGPKIFIFMRYAEKGDMLSHIK-KTGPIDEAQTKVW 163
Query: 369 AYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDS 416
+Q++ AL YL S HRD+ N+L+S VK+ DFG +RY D+
Sbjct: 162 FFQMAKALQYLHSHDIAHRDLKCENILLSKRLNVKIADFGFARYCRDA 19
>13592
Length = 980
Score = 67.4 bits (163), Expect = 3e-11, Method: Compositional matrix adjust.
Identities = 55/204 (26%), Positives = 96/204 (47%), Gaps = 8/204 (3%)
Frame = +2
Query: 322 HPHIVKLIGV-ITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLE 380
H ++V+ G+ + + I MELC+ G L S +++ L A + QL + +A L
Sbjct: 158 HKNLVRYYGIEVHREELLIFMELCSEGTLESLVELTG-GLPEALSRRFTAQLLSGVAELH 334
Query: 381 SKRFVHRDIAARNV-LVSSNDCVKLGDFGLSRYMEDSTYYKAS-KGKLPIK-WMAPE--- 434
VHRDI N+ LV ++ +KLGDFG + ++ T +G + + +MAPE
Sbjct: 335 KHGIVHRDIKTANIFLVDGSNSLKLGDFGSAVKIQAHTTVPGELQGYVGTQAYMAPEVFT 514
Query: 435 SINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNN-DVIGRIENGERLPMPPNCPPTL 493
N +D+W G + E + G +P+ +N ++ ++ GE+ P +
Sbjct: 515 KTNSDGHGRLADIWSVGCVVVE-MASGKRPWAQFDSNFQIMFKVGMGEKPQAPESLSQEG 691
Query: 494 YSLMTKCWAYDPSRRPRFTELKAQ 517
+ + C +DP +R EL Q
Sbjct: 692 HDFIDHCLQHDPKQRLSAIELLEQ 763
>31885
Length = 529
Score = 66.6 bits (161), Expect = 4e-11, Method: Compositional matrix adjust.
Identities = 46/148 (31%), Positives = 77/148 (52%), Gaps = 6/148 (4%)
Frame = -2
Query: 317 MRQFDHPHIVKL-IGVITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTA 375
+ + DHP +V L E ++++++L G+LR +Q ++ S + Y QL+
Sbjct: 510 LTRLDHPFLVNLWYAFQDEEDLFMVVDLFLGGDLRYHMQ-QEVSFREDCVKFYLCQLALV 334
Query: 376 LAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPE- 434
L YL S++ VHRDI N+L+ + DF ++ +ED ++ G P +MAPE
Sbjct: 333 LDYLRSQKIVHRDIKPDNILLDEQGHCHVTDFNIATQLEDDELATSTSGTRP--YMAPEV 160
Query: 435 ---SINFRR-FTSASDVWMFGVCMWEIL 458
+IN RR + D W GV ++E+L
Sbjct: 159 YGVAINERRGYGFPVDWWSLGVSLFELL 76
>09606
Length = 1300
Score = 63.5 bits (153), Expect = 3e-10, Method: Compositional matrix adjust.
Identities = 62/254 (24%), Positives = 105/254 (41%), Gaps = 37/254 (14%)
Frame = -3
Query: 308 PDPRNAEVTMRQFDHPHIVKLIGVI-TENPVWIIMELCTLGELRSFLQVRKYSLDLASLI 366
P+ N HP++V+ T N +W+++ELCT G L L + + L S+
Sbjct: 998 PEVTNTVRMTHDISHPNVVQFHEWYETSNHLWLVVELCTGGSLADIL-AQDHHLPETSIR 822
Query: 367 LYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRY----MEDSTYYKAS 422
+ L T L Y+ S + D+ VL+ ++ +K DFGLS+ +E+ + A
Sbjct: 821 DFGIHLVTGLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAE 642
Query: 423 KG-------------KLPIK----WMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPF 465
G ++P +MAPE + SD+W G +E + G PF
Sbjct: 641 AGDQWNIQSAEEMMKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYE-MFSGHPPF 465
Query: 466 QGVKNNDVIGRIEN---------GERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTEL-- 514
G + ++ N G RL P+ P +L+ D +RR + L
Sbjct: 464 LGETYDITKDKVLNKEFPLPKVKGSRLSAKPS--PEFLNLLESLLQKDSTRRLSWASLVK 291
Query: 515 ----KAQLSTILEE 524
+ LS++++E
Sbjct: 290 HAFWQGGLSSLVKE 249
>13066
Length = 551
Score = 63.5 bits (153), Expect = 4e-10, Method: Compositional matrix adjust.
Identities = 43/152 (28%), Positives = 75/152 (49%), Gaps = 10/152 (6%)
Frame = +3
Query: 310 PRNAEVTMRQFDHPHIVKLIGVITENPV-WIIMELCTLGELRSFLQVRKYSLDLASLILY 368
PR ++ + + DHP+I+++ ++ P +I M G+L +++Q + + + I +
Sbjct: 120 PRELDL-LTKLDHPYIIQIHSILQRXPKNFIFMRFAERGDLLTYIQEVGFVKEKQAKIWF 296
Query: 369 AYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLS---------RYMEDSTYY 419
YQ++TAL YL S HRD+ N+L+SS+ VKL DFG + +YM +
Sbjct: 297 -YQMTTALNYLHSYDVAHRDLKCENILLSSHFNVKLADFGFACACITESGEKYMSRTYCG 473
Query: 420 KASKGKLPIKWMAPESINFRRFTSASDVWMFG 451
A+ I + AP + +D W G
Sbjct: 474 SAAYAAPEIVYGAPYA------PKVADAWSLG 551
>00715
Length = 1788
Score = 62.0 bits (149), Expect = 9e-10, Method: Compositional matrix adjust.
Identities = 52/221 (23%), Positives = 96/221 (43%), Gaps = 33/221 (14%)
Frame = +1
Query: 322 HPHIVKLIGVIT----ENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALA 377
H ++V ++G + E+ W+ ME L++ L + +D + + A Q++ L
Sbjct: 103 HVNVVSILGATSLHRFEDGAWLAMEYVGPLNLQTILNDHQQDIDSSMRLSLALQMARGLH 282
Query: 378 YLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYM-------------------EDSTY 418
YL S VH D+ N L++ + +++ DFG + E +
Sbjct: 283 YLHSINIVHLDLKPANCLLTRDLKLRIADFGCCHQLTPTGLDMGEREGGMAGNELELTPV 462
Query: 419 YKASKGKLP--IKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGR 476
A K +L + + APE + + + SDV+ G+ +W++ P++GV + V+ +
Sbjct: 463 QGAWKNELAGTLAYRAPELLKGLQPSVRSDVYSLGITLWQMCTRQ-GPYEGVPAHAVVYQ 639
Query: 477 IENGERLPMPPNCPPT--------LYSLMTKCWAYDPSRRP 509
+ + + P PP P T L T+CWA RP
Sbjct: 640 VVSKDLRPCPP--PSTEDDPFEVMFRDLYTQCWARRVEDRP 756
>07833
Length = 1504
Score = 62.0 bits (149), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 51/202 (25%), Positives = 93/202 (46%), Gaps = 7/202 (3%)
Frame = -3
Query: 317 MRQFDHPHIVKLIGVITENP-VWIIMELCTLGELRSFLQVRK-YSLDLASLILYAYQLST 374
+R F+HP+++ ++ + P + +I + G L + L +D + +A ++
Sbjct: 1457 LRIFNHPNVLPVLACCNQPPNLVLISQFMPFGSLYNTLHGESGIVVDQNQSLRFAMDIAR 1278
Query: 375 ALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKL-PIKWMAP 433
+ +L S + N L++S + D M D + KGK+ WMAP
Sbjct: 1277 GMEFLHSM-----EPTIPNFLLTSKHVMIDEDLTARINMADYCFSFHEKGKVYSPAWMAP 1113
Query: 434 ESINFRR---FTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIE-NGERLPMPPNC 489
E++ R T A+D+W F + MWE+ V PF + + +V ++ G R+ +PP
Sbjct: 1112 EALQRRPDDINTRAADMWSFAILMWELETREV-PFAELSSMEVGMKVALEGLRISIPPGI 936
Query: 490 PPTLYSLMTKCWAYDPSRRPRF 511
+ L+ C +P +RPRF
Sbjct: 935 SLHMSRLIKICMNEEPGKRPRF 870
>13212
Length = 1067
Score = 61.6 bits (148), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 51/196 (26%), Positives = 84/196 (42%), Gaps = 18/196 (9%)
Frame = -1
Query: 337 VWIIMELCTL---GELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARN 393
VW I+++ + G L S + + + A + +++ AL +L +HRDI A N
Sbjct: 1067 VWXIVDVFRVLWWGALDSIMVDLEKPMTEAQICYVCHEMCMALDFLHRHHVIHRDIKAGN 888
Query: 394 VLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAP-----ESINFRRFTSASDVW 448
VL++ + VKL DFG+S + + + P WMAP E++ + +D+W
Sbjct: 887 VLLTIDGEVKLADFGVSAKNTQTQQKRDTFIGTPY-WMAPEVVLCETLKDTPYDFKADIW 711
Query: 449 MFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTL----------YSLMT 498
GV + E P + + V+ +I + PPTL +
Sbjct: 710 SLGVTLIE-FAQIEPPNKEMHPMRVLIKIHKSD--------PPTLEKPKKWTKLFKDFIA 558
Query: 499 KCWAYDPSRRPRFTEL 514
KC DP+ RP EL
Sbjct: 557 KCLVKDPNLRPTAAEL 510
>19094
Length = 898
Score = 61.2 bits (147), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 34/114 (29%), Positives = 62/114 (54%), Gaps = 3/114 (2%)
Frame = +1
Query: 347 GELRSFLQVRKYSL---DLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVK 403
G + +++R +L ++A+++ Y + L YL S+R +HRDI A N+L+++ K
Sbjct: 10 GSVSDIMRLRNKTLVEREIATILYYTLK---GL*YLHSRRKIHRDIKAGNILLNNEGHAK 180
Query: 404 LGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEI 457
L DFG++ + D+ + + P WMAPE I + +D+W G+ E+
Sbjct: 181 LADFGVAGQLTDTMAKRNTVIGTP-YWMAPEVIQEIGYDCVADIWSLGITALEM 339
>29581
Length = 1278
Score = 58.5 bits (140), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 43/147 (29%), Positives = 71/147 (48%), Gaps = 8/147 (5%)
Frame = -2
Query: 322 HPHIVKLIGVI---TENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAY 378
H +IV+L V+ + + ++++ME C +L S L + + QL L Y
Sbjct: 1178 HQNIVQLQEVVVGKSLDSLFLVMEYCE-QDLASLLDNMPAPFSESQVKCIVLQLLKGLRY 1002
Query: 379 LESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLP----IKWMAPE 434
L +HRD+ N+L++ CVK+ DFGL+R Y K K P + + APE
Sbjct: 1001 LHEAFIIHRDLKVSNLLMTDKGCVKIADFGLAR-----NYGKPQKPMTPKVVTLWYRAPE 837
Query: 435 SI-NFRRFTSASDVWMFGVCMWEILMH 460
+ + ++A D+W G + E+L H
Sbjct: 836 LLFGSKTHSTAIDMWSAGCILGELLGH 756
>19761
Length = 473
Score = 58.5 bits (140), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 34/130 (26%), Positives = 67/130 (51%), Gaps = 8/130 (6%)
Frame = -3
Query: 365 LILYAYQLSTALAYLESKR--FVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKAS 422
++ + Q ++AL Y+ + +HRD+ +N+ V+ V+LGD GL+R + + S
Sbjct: 417 IVCWLMQTASALNYMHTHTPVILHRDLKPQNIYVTEKGDVRLGDLGLARKLTGPADFATS 238
Query: 423 KGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIG------R 476
+ I +++PE ++ + + S SD+W G ++I G K +D +G +
Sbjct: 237 QVG-TIMYLSPEILSQQPYNSKSDIWSLGCVFYDI--------TGKKGSDEMGVMFLLVQ 85
Query: 477 IENGERLPMP 486
+ G +LP+P
Sbjct: 84 VMGGRKLPLP 55
>14126
Length = 1265
Score = 58.2 bits (139), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 48/185 (25%), Positives = 87/185 (47%), Gaps = 14/185 (7%)
Frame = +3
Query: 317 MRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVRKYSLDLASLIL--------- 367
+ Q++HP++V+L+ V + N + T E+R L DLA+ +
Sbjct: 360 LEQYEHPNVVRLLDV-SHNTI-------TDREIRLNLVFEYIEHDLATYLAKCPSPGLGP 515
Query: 368 -----YAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKAS 422
QL + +L S R VHRD+ +N+L+S + +KL DFGL+R S + +
Sbjct: 516 DRIKDLMLQLLNGVDFLHSNRIVHRDLKPQNLLISKDGRLKLADFGLARIY--SFHMALT 689
Query: 423 KGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGER 482
+ + + +PE + + ++ D+W G C++ L F+G D + +I E
Sbjct: 690 TVVVTLWYRSPEVLMQAEYGTSVDIWSCG-CIFAELFTRRALFKGSSEFDQLKKI--FEV 860
Query: 483 LPMPP 487
+ +PP
Sbjct: 861 IGLPP 875
>04591
Length = 1117
Score = 57.0 bits (136), Expect = 4e-08, Method: Compositional matrix adjust.
Identities = 41/152 (26%), Positives = 69/152 (45%), Gaps = 11/152 (7%)
Frame = -2
Query: 317 MRQFDHPHIVKLIGVI---------TENPVWIIMELCTLGELRSFLQVRKYSLDLASLIL 367
++Q +H ++V+L + ++ ++I E C +L L + LA
Sbjct: 1059 LQQLEHENVVQLQEICHTQAGPYNRYKSTFYLIFEYCDY-DLAGLLNNLRVKFSLADKKN 883
Query: 368 YAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLP 427
QL L Y+ +K+ +HRDI A N+L++ + +KL DFGLSR S K ++
Sbjct: 882 LMSQLLNGLFYIHTKQILHRDIKAANILLTRDGVLKLADFGLSRPWVKS---KRLTNRVV 712
Query: 428 IKWMAPESINF--RRFTSASDVWMFGVCMWEI 457
W P + R + D+W G M E+
Sbjct: 711 TLWYRPPELLLGEREYGPEIDMWGVGCIMAEM 616
>21079
Length = 878
Score = 56.2 bits (134), Expect = 5e-08, Method: Compositional matrix adjust.
Identities = 34/128 (26%), Positives = 66/128 (51%), Gaps = 2/128 (1%)
Frame = +1
Query: 339 IIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSS 398
++ME GEL + + L + + Q+ + + Y+ ++ +H D+ NVL S
Sbjct: 55 LVMEFVGAGELFERVIRDDFVLTERDCVHFVRQICSGVGYMHTQSILHLDLKPENVLCVS 234
Query: 399 NDC--VKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWE 456
++ +K+ DFGL+R+ + + G P +++APE +N+ +D+W GV +
Sbjct: 235 DNSNQIKIIDFGLARFYKPGDSLQVLFGT-P-EFIAPEVVNYDEINFTTDMWSIGVICY- 405
Query: 457 ILMHGVKP 464
IL+ G+ P
Sbjct: 406 ILLSGLSP 429
>01060
Length = 1800
Score = 55.5 bits (132), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 37/148 (25%), Positives = 78/148 (52%), Gaps = 5/148 (3%)
Frame = +1
Query: 317 MRQFDHPHIVKLIGVITENP-VWIIMELCTLGELRSFLQV--RKYSLDLASLILYAYQLS 373
+R+ H +IV L VI E+ ++++ E ++ +L+ ++ LD + Y +Q+
Sbjct: 232 LRELRHTNIVCLEDVIMEDERLFLVFEFLSM-DLKMYIDKFPEGVVLDRRLVKSYVFQIV 408
Query: 374 TALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWM-A 432
T + + +R VHRD+ +N+L++ +K+ DFG++R + +A ++ W A
Sbjct: 409 TGIXFCHQRRIVHRDLKPQNLLINHTGAIKIADFGMARTF--ALPVRAYTHEVVTLWYRA 582
Query: 433 PESI-NFRRFTSASDVWMFGVCMWEILM 459
PE + ++++ DVW G ++L+
Sbjct: 583 PEILMGASKYSTPVDVWSIGTIFADMLI 666
>18484
Length = 635
Score = 55.1 bits (131), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 28/113 (24%), Positives = 59/113 (52%)
Frame = +1
Query: 367 LYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKL 426
YA +++ L +L + ++RD+ NV++ S +K+ DFG+ + +
Sbjct: 55 FYAAEIAVGLFFLHDQGIIYRDLKLDNVMLDSEGHIKIADFGMCKEGMTGDATTRTFCGT 234
Query: 427 PIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIEN 479
P ++APE + ++ ++ + D W +GV ++E+L G PF G +++ I +
Sbjct: 235 P-DYIAPEIVLYQPYSKSVDWWAYGVLLFEMLA-GQPPFDGEDEDELFSSITD 387
>03240
Length = 1683
Score = 53.5 bits (127), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 49/190 (25%), Positives = 80/190 (42%), Gaps = 45/190 (23%)
Frame = -3
Query: 321 DHPHIVKLIGVITE-NPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYL 379
D+ +VKL + N ++ +M+ G+L L +R LD Y +L A+ +
Sbjct: 1117 DNEWVVKLYYSFQDHNYLYFVMDYVPGGDLMGLL-IRMEILDEPLARFYVAELVQAIESV 941
Query: 380 ESKRFVHRDIAARNVLVSSNDCVKLGDFGLS---RYMEDSTYYK-----ASKGKLPIK-- 429
F+HRDI N+L+ N +KL DFGL R+ +S YY+ A + + +K
Sbjct: 940 HRMGFIHRDIKPDNILIDRNGHIKLTDFGLCTGFRWTHNSKYYQRDGTHARQDSMEVKCQ 761
Query: 430 ---------------------------------WMAPESIN-FRRFTSASDVWMFGVCMW 455
++APE ++ +TS D W GV ++
Sbjct: 760 LDEQCQCEILKPLERRRKREQRCLAHSLVGTPNYIAPEVLSRLGGYTSVCDWWSVGVILF 581
Query: 456 EILMHGVKPF 465
E+L+ G PF
Sbjct: 580 EMLV-GHPPF 554
>07836
Length = 1478
Score = 53.5 bits (127), Expect = 4e-07, Method: Compositional matrix adjust.
Identities = 56/215 (26%), Positives = 93/215 (43%), Gaps = 38/215 (17%)
Frame = -1
Query: 347 GELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRF--------VHRDIAARNVLVSS 398
G L +L R LD + ++ A+ LA+L + F HRDI ++N+LV
Sbjct: 1298 GSLHDYLLSR--VLDSSEMLALAHSAICGLAHLHIEIFGTRGKPAIAHRDIKSKNILVKK 1125
Query: 399 NDCVKLGDFGLS-RYMEDSTYYKASKG--KLPIKWMAPESI-------NFRRFTSASDVW 448
N + D GL+ RY+ +S + + ++MAPE + NF F A D++
Sbjct: 1124 NGTCCIADLGLAVRYISESNEVDVAPNPRQGTKRYMAPEVLEMLLNVKNFDAFKQA-DMY 948
Query: 449 MFGVCMWEI----LMHGVK-----PFQGVKNND--------VIGRIENGERLPMPPNCPP 491
FG+ MWEI ++ GV PF +D V+ + +P+ P
Sbjct: 947 AFGLVMWEIARCCVIGGVAEEYQVPFYNCLPHDPSFEDVRLVVSVDKVRPDIPLRWQEDP 768
Query: 492 ---TLYSLMTKCWAYDPSRRPRFTELKAQLSTILE 523
+ +M +CW+ +P+ R +K L + E
Sbjct: 767 IMKVMVKVMCECWSGNPAARLTALRVKKTLGKLSE 663
>01756
Length = 1858
Score = 50.8 bits (120), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 35/153 (22%), Positives = 68/153 (44%), Gaps = 12/153 (7%)
Frame = -3
Query: 317 MRQFDHPHIVKLIGVIT---------ENPVWIIMELCTLGELRSFLQVRKYSLDLASLIL 367
++ +H ++V LI + + ++ +++ E C +L L +L +
Sbjct: 1583 LQLLNHENVVDLIEICSTKATSANRYKSMFYLVFEFCE-HDLAGLLSNMSVVFNLPEIKE 1407
Query: 368 YAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSR-YMEDSTYYKASKGKL 426
QL L Y+ + +HRD+ A N+L++ +KL DFGL+R + + ++
Sbjct: 1406 VMKQLMNGLYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRV 1227
Query: 427 PIKWMAPESINF--RRFTSASDVWMFGVCMWEI 457
W P + R +++A D W G M E+
Sbjct: 1226 VTLWYRPPELLLGDRNYSTAIDQWGAGCIMAEM 1128
>15910
Length = 1361
Score = 50.8 bits (120), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 34/107 (31%), Positives = 55/107 (51%), Gaps = 3/107 (2%)
Frame = +2
Query: 378 YLESKRFVHRDIAARNVL---VSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPE 434
Y+ + VHRD+ N+L ++ + +KL DFGLSR +E G P + APE
Sbjct: 509 YIHANGVVHRDLKPENLLYECMTDDSKLKLADFGLSRIIEPEVQMSTVCGT-P-GYCAPE 682
Query: 435 SINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGE 481
+ ++T + D+W GV + IL+ G +PF ++ +I GE
Sbjct: 683 VLKGDKYTPSVDMWSVGVIAY-ILLCGYEPFFAENEFEMYRKIIKGE 820
>01966
Length = 1735
Score = 50.4 bits (119), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 27/98 (27%), Positives = 56/98 (57%), Gaps = 3/98 (3%)
Frame = -1
Query: 317 MRQFDHPHIVKLIGVITENP-VWIIMELCTLGELRSFLQV--RKYSLDLASLILYAYQLS 373
+R+ H +IV L VI E+ ++++ E ++ +L+ ++ LD + Y +Q+
Sbjct: 1552 LRELRHTNIVCLEDVIMEDERLFLVFEFLSM-DLKMYIDKFPEGVVLDRRLVKSYVFQIV 1376
Query: 374 TALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSR 411
T + + +R VHRD+ +N+L++ +K+ DFG++R
Sbjct: 1375 TGINFCHQRRIVHRDLKPQNLLINHTGAIKIADFGMAR 1262
>26711
Length = 405
Score = 50.4 bits (119), Expect = 3e-06, Method: Composition-based stats.
Identities = 32/102 (31%), Positives = 58/102 (56%), Gaps = 5/102 (4%)
Frame = -2
Query: 371 QLSTALAYLESKRFVHRDIAARNVLVSSN--DCVKLGDFGLSRYM---EDSTYYKASKGK 425
Q+ L ++ ++ VH D+ N+L+S + D V+L DFGL+R + +++ + G
Sbjct: 392 QVLDILQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARKLYPPQETFLNHGTPG- 216
Query: 426 LPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQG 467
+ +PE+++ + ++ASDVW GV + IL+ G PFQ
Sbjct: 215 ----FTSPEALDVKPISTASDVWGVGVLAY-ILLSGQSPFQA 105
>25550
Length = 941
Score = 49.3 bits (116), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 25/76 (32%), Positives = 37/76 (48%), Gaps = 1/76 (1%)
Frame = +3
Query: 450 FGVC-MWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRR 508
G C +W++ + GV +V +E G R+ P P +Y LM KCW +DP R
Sbjct: 12 MGACDIWDVX------YPGVDLTEVYHLLERGYRMERPQGTPADVYILMLKCWQWDPKER 173
Query: 509 PRFTELKAQLSTILEE 524
P F E+ L + E+
Sbjct: 174 PTFKEIHYLLENMFEK 221
>12672
Length = 773
Score = 49.3 bits (116), Expect = 8e-06, Method: Compositional matrix adjust.
Identities = 38/162 (23%), Positives = 69/162 (42%), Gaps = 16/162 (9%)
Frame = +3
Query: 373 STALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGL---SRYMEDSTYYKASKGKLPIK 429
++ + YL VHRDI N+L+ S K+GDF + E T AS
Sbjct: 21 ASGIQYLNDNGHVHRDIKTANILLDSEYTAKVGDFATVVSAPSGEGKTVQNASVVIGTAA 200
Query: 430 WMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPF----QGVKNNDVIGRIENGERL-- 483
++APE+I+F ++ D + FGV + E++ V + ++ ++ +E E +
Sbjct: 201 YLAPEAIHF-DVSTKLDSYSFGVVLLEVITGLVAQDYSREERTLSSHIMENVEEPEEIHD 377
Query: 484 -------PMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQL 518
P LY + +C +RP +++ +L
Sbjct: 378 FVDQSAGTWPDGAVDKLYDISMRCLNLSKKQRPNVKDIRPEL 503
>32264
Length = 287
Score = 48.9 bits (115), Expect = 9e-06, Method: Compositional matrix adjust.
Identities = 21/48 (43%), Positives = 28/48 (58%)
Frame = +1
Query: 477 IENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEE 524
IE+G RL P P ++Y LM +CW Y P +RP F EL L I+ +
Sbjct: 1 IEDGYRLQQNPQTPDSVYKLMLRCWEYVPEKRPHFKELYTSLKDIVRK 144
>21433
Length = 590
Score = 48.1 bits (113), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 30/98 (30%), Positives = 49/98 (50%)
Frame = +2
Query: 368 YAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLP 427
Y YQLS+AL Y ++ +HRDI N+L+ +K+ DFG S + S + +
Sbjct: 182 YIYQLSSALEYCHYRKVIHRDIKPENLLLGLKGDLKIADFGWSVHAPSS---RRTTMCGT 352
Query: 428 IKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPF 465
+ ++ PE + + D+W GV +E L+ G P
Sbjct: 353 LDYLPPEMVEGKTHDENVDLWSLGVLCYEFLV-GTPPL 463
>01707
Length = 757
Score = 47.4 bits (111), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 44/165 (26%), Positives = 73/165 (44%), Gaps = 15/165 (9%)
Frame = +1
Query: 309 DPRNAEVTMR------QFDHPHIVKLIGVITENP----VWIIMELCTLGELRSFLQVRKY 358
DP ++ MR Q HP++V+LI V V+ ++ L EL + R
Sbjct: 181 DPLIKKIAMREIRMLKQLKHPNLVRLIEVFRRKKRLHLVFDYVDHTLLNELDRY--PRGL 354
Query: 359 SLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYM----E 414
+ I+Y Q A+ + +HRD+ N+L++ VKL DFG +R + +
Sbjct: 355 PEPMVKRIIY--QTLLAVNFCHQYNTIHRDVKPENILITRQGQVKLCDFGFARILTGPGD 528
Query: 415 DSTYYKASKGKLPIKWMAPE-SINFRRFTSASDVWMFGVCMWEIL 458
+ T Y A++ + APE + ++ DVW G E+L
Sbjct: 529 EYTDYVATRW-----YRAPELLVGDTQYGPPVDVWAIGCVFAELL 648
>26560
Length = 398
Score = 44.3 bits (103), Expect = 2e-04, Method: Composition-based stats.
Identities = 34/113 (30%), Positives = 59/113 (52%), Gaps = 1/113 (0%)
Frame = -1
Query: 367 LYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKL 426
YA ++ L ++ S+ V+RD+ N+L+ N V++ D GL+ + AS G
Sbjct: 344 FYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGLACDFSKKRPH-ASVGTH 168
Query: 427 PIKWMAPESI-NFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIE 478
+MAPE + + + S++D + FG CM L+ G PF+ ++N RI+
Sbjct: 167 --GYMAPEVLMKGQSYDSSADWFSFG-CMLYKLLKGHSPFR--QHNQGQARID 24
>04138
Length = 800
Score = 43.5 bits (101), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 24/85 (28%), Positives = 42/85 (49%), Gaps = 3/85 (3%)
Frame = +1
Query: 376 LAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSR-YMEDSTYYKASKGKLPIKWMAPE 434
L Y+ + +HRD+ A N+L++ +KL DFGL+R + + ++ W P
Sbjct: 52 LYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRPP 231
Query: 435 SINF--RRFTSASDVWMFGVCMWEI 457
+ R +++A D W G M E+
Sbjct: 232 ELLLGDRNYSTAIDQWGAGCIMAEM 306
>01392
Length = 1806
Score = 42.4 bits (98), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 37/123 (30%), Positives = 59/123 (47%), Gaps = 12/123 (9%)
Frame = -1
Query: 363 ASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSND---CVKLGDFGLSRYME-DSTY 418
ASL++ ++ AL +L SK HRD+ N+L D VK+ DF L+ + D
Sbjct: 1785 ASLVVR--HIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGISCDGDG 1612
Query: 419 YKASKGKLPI---KWMAPESINFRRFTSAS-----DVWMFGVCMWEILMHGVKPFQGVKN 470
K + P+ ++MAPE ++ S S D+W G+ ++ I++ G PF G
Sbjct: 1611 TKTPELLTPVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILY-IMLCGYPPFYGQCG 1435
Query: 471 NDV 473
D
Sbjct: 1434 EDC 1426
>12786
Length = 460
Score = 41.2 bits (95), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 39/143 (27%), Positives = 69/143 (48%), Gaps = 23/143 (16%)
Frame = -3
Query: 359 SLDLASLILYAYQLSTALAYLESKRFVHRDIAARN-VLVSSNDCVKLGDFGLSRYMED-- 415
LD + Y ++ A+ L ++ +H D+ N +LV+ N +KL DFG++ ++
Sbjct: 422 GLDRMMIKFYWREMLRAVKALHNEGVIHSDLKPANFMLVAGN--LKLIDFGIANTLQQDK 249
Query: 416 STYYKASKGKLPIKWMAPESINFRRFTSA--------------------SDVWMFGVCMW 455
++ K S+ P +M+PE+I SA SDVW G C+
Sbjct: 248 TSVLKDSRVGTP-SYMSPEAIMAACDDSADDSMEEDGHRTKPKYKVGVRSDVWSLG-CIL 75
Query: 456 EILMHGVKPFQGVKNNDVIGRIE 478
+++G PFQ +KNN +G+++
Sbjct: 74 YNMVYGRTPFQHIKNN--MGKLQ 12
>07933
Length = 728
Score = 40.0 bits (92), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 15/39 (38%), Positives = 26/39 (66%)
Frame = +3
Query: 486 PPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEE 524
P CP LY++M +CW+ +PS RP F +L+ + ++E+
Sbjct: 3 PNYCPNLLYNIMMQCWSAEPSARPTFHKLEQDIVAMVEQ 119
>03508
Length = 1463
Score = 40.0 bits (92), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 26/100 (26%), Positives = 48/100 (48%), Gaps = 2/100 (2%)
Frame = +1
Query: 367 LYAYQLSTALAYLESKRFVHRDIAARNVLVS-SNDCVKLGDFGLSRYMEDSTYYKASKGK 425
Y Y+L AL + S +HRD+ NV++ N ++L D+GL+ + Y
Sbjct: 883 FYLYELMKALDFCHSMGIMHRDVKPHNVMIDHENKKLRLIDWGLAEFYHPGMEYNVRVAS 1062
Query: 426 LPIKWMAPE-SINFRRFTSASDVWMFGVCMWEILMHGVKP 464
K PE ++++ + + D+W G CM+ ++ +P
Sbjct: 1063RYFK--GPELLLDYQMYDYSLDMWSLG-CMFASMIFRKEP 1173
>28157
Length = 400
Score = 38.9 bits (89), Expect = 0.009, Method: Compositional matrix adjust.
Identities = 27/98 (27%), Positives = 46/98 (46%), Gaps = 6/98 (6%)
Frame = +3
Query: 317 MRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVR--KYSLDLASLILYAYQLST 374
+ + HP+IV L G ++PV ++ME G L + L + A + + Q +
Sbjct: 72 LSRVSHPNIVCLYGACRDHPVCLVMEYAEGGSLYNVLHGSGPQPQYTAAHAMNWLLQCAL 251
Query: 375 ALAYLES---KRFVHRDIAARN-VLVSSNDCVKLGDFG 408
+ YL K +HRD+ N +L+ +K+ DFG
Sbjct: 252 GVEYLHGMKPKALIHRDLKPPNLLLIQCGTKLKICDFG 365
>37602
Length = 804
Score = 38.5 bits (88), Expect = 0.013, Method: Compositional matrix adjust.
Identities = 22/71 (30%), Positives = 32/71 (45%)
Frame = -1
Query: 337 VWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLV 396
+WI ME C G ++ V L + + L YL + +HRDI N+L+
Sbjct: 294 LWIAMEYCGGGSMQDIYHVTG-PLTEPQIAFVCRETLKGLHYLHRRGKMHRDIKGANILL 118
Query: 397 SSNDCVKLGDF 407
+ VKL DF
Sbjct: 117 TEEGDVKLADF 85
>38046
Length = 446
Score = 38.1 bits (87), Expect = 0.015, Method: Composition-based stats.
Identities = 14/32 (43%), Positives = 24/32 (75%)
Frame = -1
Query: 372 LSTALAYLESKRFVHRDIAARNVLVSSNDCVK 403
++ A+AY+E + F+HR++ RN+LV N+ VK
Sbjct: 98 IADAMAYMEKENFIHRNLGDRNILVGPNNRVK 3
>18481
Length = 437
Score = 37.7 bits (86), Expect = 0.018, Method: Composition-based stats.
Identities = 26/82 (31%), Positives = 44/82 (53%), Gaps = 4/82 (4%)
Frame = -1
Query: 339 IIMELCTLG-ELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVS 397
++MEL LG L + K L ++++ + QL + L ++ K F+HRD+ N L+
Sbjct: 266 LVMEL--LGPSLEELFVICKRRFTLKTILMVSDQLLSRLEFIHQKCFIHRDLKPDNFLMG 93
Query: 398 -SNDCVKLG--DFGLSRYMEDS 416
C +L DFGLS+ +D+
Sbjct: 92 LGRHCHRLYIIDFGLSKRYKDT 27
>11185
Length = 473
Score = 37.4 bits (85), Expect = 0.024, Method: Compositional matrix adjust.
Identities = 37/168 (22%), Positives = 62/168 (36%), Gaps = 21/168 (12%)
Frame = +1
Query: 368 YAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRY----MEDSTYYKASK 423
+ L T L Y+ S + D+ VL+ ++ +K DFGLS+ +E+ + A
Sbjct: 16 FGIHLVTGLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEA 195
Query: 424 G-------------KLPIK----WMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQ 466
G ++P +MAPE + SD+W G +E+
Sbjct: 196 GDQWNIQSAEEMMKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMF-------- 351
Query: 467 GVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTEL 514
+G RL P+ P +L+ D +RR + L
Sbjct: 352 ------------SGSRLSAKPS--PEFLNLLESLLQKDSTRRLSWASL 453
>00486
Length = 797
Score = 35.4 bits (80), Expect = 0.12, Method: Compositional matrix adjust.
Identities = 24/81 (29%), Positives = 36/81 (44%)
Frame = -2
Query: 428 IKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPP 487
I++MAPE + A D W G M+++L G PF I +I G +L +PP
Sbjct: 766 IEYMAPEILTRTGHGKAVDWWSLGALMYDMLT-GSPPFTAENRKKTIDKILKG-KLNLPP 593
Query: 488 NCPPTLYSLMTKCWAYDPSRR 508
L+ K +P+ R
Sbjct: 592 YLTNEARGLIKKLLRKNPAER 530
>26009
Length = 886
Score = 34.7 bits (78), Expect = 0.17, Method: Compositional matrix adjust.
Identities = 15/30 (50%), Positives = 21/30 (70%)
Frame = +3
Query: 371 QLSTALAYLESKRFVHRDIAARNVLVSSND 400
QL +AL ++ SK+ VHRDI NVL+ + D
Sbjct: 735 QLVSALDFMHSKQLVHRDIKPENVLILTPD 824
>16708
Length = 1397
Score = 33.9 bits (76), Expect = 0.26, Method: Compositional matrix adjust.
Identities = 17/49 (34%), Positives = 27/49 (55%)
Frame = -1
Query: 363 ASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSR 411
A + A Q AL ++ VH D+ A NVLV ++ KL D+G+++
Sbjct: 1094 AMVCCIAGQXVCALEHIHELGVVHMDVKADNVLVDAHGNCKLTDYGIAQ 948
>27287
Length = 514
Score = 33.9 bits (76), Expect = 0.28, Method: Compositional matrix adjust.
Identities = 13/37 (35%), Positives = 20/37 (54%)
Frame = -2
Query: 486 PPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTIL 522
PP ++ +M CW DP+ RP F+ L +L +L
Sbjct: 504 PPYASSEMFGIMHSCWQEDPNDRPSFSRLVQELDKML 394
>15741
Length = 402
Score = 33.9 bits (76), Expect = 0.30, Method: Composition-based stats.
Identities = 15/44 (34%), Positives = 24/44 (54%)
Frame = -3
Query: 352 FLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVL 395
FL L +A ++ +A++ + + VHRD+AARNVL
Sbjct: 133 FLTSTANDLTARDFFSFALHVARGMAHVANNKIVHRDVAARNVL 2
>27405
Length = 532
Score = 33.9 bits (76), Expect = 0.30, Method: Compositional matrix adjust.
Identities = 14/44 (31%), Positives = 26/44 (59%)
Frame = -3
Query: 367 LYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLS 410
YA ++ L ++ S+ V+RD+ N+L+ N V++ D GL+
Sbjct: 242 FYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGLA 111
>02638
Length = 1490
Score = 33.5 bits (75), Expect = 0.36, Method: Compositional matrix adjust.
Identities = 28/92 (30%), Positives = 42/92 (45%), Gaps = 5/92 (5%)
Frame = +1
Query: 428 IKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKP---FQGVKNN-DVIGRIENG-ER 482
I +MAPE + + A DVW G M E M +P + N+ +I +I + +
Sbjct: 28 IAFMAPEVLRGESYGRACDVWSVGCVMIE--MCTCRPPWNSHDISNHLALIFKIASSVDP 201
Query: 483 LPMPPNCPPTLYSLMTKCWAYDPSRRPRFTEL 514
P+P N P + LM +C D RP +L
Sbjct: 202 PPIPENMSPPVRDLMLRCLEQDSDFRPSAKDL 297
>21210
Length = 518
Score = 33.5 bits (75), Expect = 0.37, Method: Compositional matrix adjust.
Identities = 30/104 (28%), Positives = 47/104 (45%), Gaps = 7/104 (6%)
Frame = +3
Query: 430 WMAPESINFRR----FTSASDVWMFGVCMWEILMHGVKPFQG-VKNNDVIGRIENGER-- 482
+MAPE I+ R + SDVW G+ + E L G P++ V D + ++ G
Sbjct: 18 YMAPERIDPRASSHGYDVRSDVWSLGITLME-LATGRFPYRKWVSIFDQLQQVVRGVAPC 194
Query: 483 LPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEK 526
LP + + KC D +RP++ +L A L EE+
Sbjct: 195 LPHDGAFSHDFVNFVNKCLTKDEKQRPKYNKLLAHPFVRLYEEQ 326
>25019
Length = 730
Score = 31.6 bits (70), Expect = 1.6, Method: Composition-based stats.
Identities = 22/62 (35%), Positives = 29/62 (46%)
Frame = +3
Query: 390 AARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWM 449
AA NVL+ + VKL DFGL + T + I++MAPE + A D W
Sbjct: 255 AAENVLLDKDGHVKLTDFGLCKEAITGTRVTHTFCG-TIEYMAPEILTRTGHGKAVDWWS 431
Query: 450 FG 451
G
Sbjct: 432 LG 437
>06601
Length = 737
Score = 29.6 bits (65), Expect = 5.6, Method: Composition-based stats.
Identities = 19/51 (37%), Positives = 24/51 (47%)
Frame = +1
Query: 26 LDSVKAKTLRKLIQQTFRQFANLNREESILKFFEILSPVYRFDKECFKCAL 76
L S K KT L+ T+ LNR K F++ V+RF K C C L
Sbjct: 139 LRSAKTKTCESLVVSTYFY---LNRNA---KHFQLGKSVFRFHKMCLICVL 273
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000342839 | hsapiens_gene_ensembl | Focal adhesion
kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK) (Protein- tyrosine kinase
2). [Source:Uniprot/SWISSPROT;Acc:Q05397]
(553 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
06405 204 1e-52
21808 184 8e-47
11780 110 7e-42
09007 160 9e-40
04852 152 3e-37
07291 136 3e-32
14116 131 6e-31
17300 123 3e-30
20640 125 6e-29
08294 118 6e-27
07940 118 6e-27
18996 110 2e-24
14477 95 6e-20
17637 90 2e-18
22005 87 2e-17
18921 86 3e-17
17253 82 4e-16
13305 82 5e-16
01718 79 4e-15
00300 78 8e-15
19301 75 1e-13
12721 74 1e-13
14420 70 3e-12
30755 69 4e-12
27546 69 4e-12
13592 69 4e-12
31885 67 2e-11
09606 65 8e-11
13066 64 2e-10
07833 63 3e-10
00715 63 4e-10
19094 62 6e-10
13212 61 9e-10
29581 59 4e-09
19761 59 5e-09
14126 58 1e-08
04591 57 3e-08
21079 57 3e-08
01060 56 4e-08
07836 55 5e-08
18484 55 6e-08
03240 54 2e-07
26711 52 9e-07
15910 51 1e-06
01756 51 1e-06
01966 51 1e-06
12672 49 4e-06
25550 48 9e-06
21433 48 9e-06
01707 47 2e-05
32264 46 3e-05
26560 45 1e-04
04138 44 2e-04
01392 42 5e-04
12786 41 0.001
03508 40 0.003
37602 39 0.006
28157 39 0.006
38046 38 0.009
18481 38 0.010
11185 38 0.011
07933 37 0.018
00486 37 0.029
26009 35 0.089
27405 34 0.13
16708 34 0.13
02638 34 0.17
15741 34 0.17
21210 32 0.57
27287 32 0.60
25019 32 0.79
30593 28 7.2
06601 28 8.1
>06405
Length = 1965
Score = 204 bits (518), Expect = 1e-52, Method: Compositional matrix adjust.
Identities = 107/293 (36%), Positives = 161/293 (54%), Gaps = 2/293 (0%)
Frame = +1
Query: 228 PSTRDYEIQRERIELGRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFL 287
P +EI+R I + +G GQ+GDV++ ++ VA+KT K T FL
Sbjct: 229 PEPDRWEIERTEIAMKHRLGGGQYGDVYEAMWKRYNK---IVAVKTLKEDTM--ALNDFL 393
Query: 288 QEACHYTSLHWNWCRYISDPNVDCPDPRNAEVTMRQFDHPHIVKLIGVIT-ENPVWIIME 346
+EA M++ HP++V+L+GV T E P +I+ E
Sbjct: 394 EEAA----------------------------IMKEMKHPNLVQLLGVCTREPPFYIVTE 489
Query: 347 LCTLGELRSFLQVRKYSLDLASLILY-AYQLSTALAYLESKRFVHRDIAARNVLVSSNDC 405
G L +L+ + + ++Y A Q+++ +AYLE+K F+HRD+AARN LV+ ++
Sbjct: 490 FMPHGNLLDYLRSSTREENGPTALMYMATQIASGMAYLETKNFIHRDLAARNCLVADSNM 669
Query: 406 VKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHG 465
VK+ DFGL+R M+D TY K PIKW APE + F RF++ SD+W FGV +WE+ +G
Sbjct: 670 VKVADFGLARLMKDDTYTAHIGAKFPIKWTAPEGLAFNRFSTRSDIWAFGVLLWELATYG 849
Query: 466 VKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTEL 518
+ P+ GV+ +V +E G R+ PP P +Y LM KCW +DP RP F E+
Sbjct: 850 MSPYPGVELTEVYHLLERGYRMERPPGTPADVYILMLKCWQWDPKDRPTFKEI 1008
>21808
Length = 1011
Score = 184 bits (467), Expect = 8e-47, Method: Compositional matrix adjust.
Identities = 87/207 (42%), Positives = 132/207 (63%), Gaps = 4/207 (1%)
Frame = +1
Query: 313 DPRN--AEV-TMRQFDHPHIVKLIGVITEN-PVWIIMELCTLGELRSFLQVRKYSLDLAS 368
DP++ AE M++ HP +++L V T++ P++II EL G L FLQ + L L +
Sbjct: 61 DPKDFLAEAQIMKKLRHPKLIQLYAVCTQDDPIFIITELMKNGSLLEFLQGKGRVLKLPA 240
Query: 369 LILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKG 428
LI Q++ +AYLES+ ++HRD+AARN+LVS N+ VK+ DFGL+R +++ Y
Sbjct: 241 LIDIGAQIACGMAYLESQNYIHRDLAARNILVSDNNTVKIADFGLARVIKEDEYEARVGA 420
Query: 429 KLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLP 488
+ PIKW APE+ N+ RFT SDVW FG+ + E + +G P+ G+ N +V+ ++E+G R+P
Sbjct: 421 RFPIKWTAPEAANYNRFTIKSDVWSFGILLTETVTYGRVPYPGMTNAEVLHQVEHGYRMP 600
Query: 489 MPPNCPPTLYSLMTKCWAYDPSRRPRF 515
PP CP LY +M +CW + RP
Sbjct: 601 CPPGCPKPLYDIMLECWRKEEMERPHL 681
>11780
Length = 1713
Score = 110 bits (274), Expect(2) = 7e-42, Method: Compositional matrix adjust.
Identities = 71/207 (34%), Positives = 104/207 (50%), Gaps = 1/207 (0%)
Frame = +3
Query: 235 IQRERIELGRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEACHYT 294
I + +E+G IG+G FGDV++G+Y VAIK K+ D + FLQEA T
Sbjct: 588 IAXQDLEIGEAIGKGDFGDVYKGMYRGQ-----PVAIKQLKD--KDRGEQSFLQEASVMT 746
Query: 295 SLHWNWCRYISDPNVDCPDPRNAEVTMRQFDHPHIVKLIGVITENPVWIIMELCTLGELR 354
SL H ++V+LIGV+ ++++ E G L
Sbjct: 747 SLR----------------------------HDNLVRLIGVVLGETIFLVTEFMGKGNLV 842
Query: 355 SFLQVRKYS-LDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGL 413
+L+ R S + I +A A+ YLESKR VHRD+AARNVLV + K+ DFGL
Sbjct: 843 EYLRSRGRSVITKKDQINFATDTCAAMEYLESKRLVHRDLAARNVLVHDDGKAKVSDFGL 1022
Query: 414 SRYMEDSTYYKASKGKLPIKWMAPESI 440
+++ + + + K PIKW APE++
Sbjct: 1023AKFGD----FSQTSVKFPIKWTAPEAL 1091
Score = 79.0 bits (193), Expect(2) = 7e-42, Method: Compositional matrix adjust.
Identities = 34/82 (41%), Positives = 50/82 (60%)
Frame = +1
Query: 444 RFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTK 503
+FTS SD+W FG+ +WEI G P+ + DV+ +E G R+ P CPP +YS+M +
Sbjct: 1102 KFTSKSDMWSFGILLWEIYSFGRVPYPRIPLTDVVMHVERGYRMEAPEGCPPEIYSIMKQ 1281
Query: 504 CWAYDPSRRPRFTELKAQLSFQ 525
W DP+ RP F + A+L+ Q
Sbjct: 1282 AWELDPNERPTFKSVLARLNNQ 1347
>09007
Length = 1440
Score = 160 bits (406), Expect = 9e-40, Method: Compositional matrix adjust.
Identities = 99/314 (31%), Positives = 152/314 (48%), Gaps = 11/314 (3%)
Frame = -1
Query: 228 PSTRDYEIQRERIELGRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFL 287
P+ I ++ + L + +G+G FG V Q I+ + + VA+K C S K
Sbjct: 909 PARGKQLISKDCVALSKSLGQGHFGTVRQAIWTAESGEKVQVAVK----CLSKDKIHKDG 742
Query: 288 QEACHYTSLHWNWCRYISDPNVDCPDPRNAEVTMRQFDHPHIVKLIGVITENPVWIIMEL 347
QE T++ M+ DH +IV++ GV+ +N IM +
Sbjct: 741 QEFLKETAI------------------------MQMLDHENIVRVYGVVMDNGA-DIMLV 637
Query: 348 CTLGELRSFLQVRK-----YSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSS 402
L +RS L+ K + L ++ Q+ ++YLESKR VHRD+AARN+L+ S
Sbjct: 636 TELAPMRSLLECVKEVSARVDFSVPRLCDFSQQVCDGMSYLESKRLVHRDLAARNILLFS 457
Query: 403 NDCVKLGDFGLSRYMEDSTYYKASKGKL----PIKWMAPESINFRRFTSASDVWMFGVCM 458
VK+ D G+S + Y S+ + + W APES F+SASDVW FGV +
Sbjct: 456 KSKVKISDVGVSGALGAGKEYYQSQQTIHLQNAVAWCAPESFRNLCFSSASDVWAFGVLL 277
Query: 459 WEILMHGVKPFQGVKNNDVIGRIE--NGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFT 516
WE HG +P+ G+ ++ ++ +RL P CP Y++M KCW +P RRP F+
Sbjct: 276 WEFFTHGFQPWAGLNGQQIMEAVDAPQSQRLEQPDLCPKEYYAVMLKCWEQEPQRRPTFS 97
Query: 517 ELKAQLSFQNPAQM 530
+L L P Q+
Sbjct: 96 QLFLTLPQIRPIQV 55
>04852
Length = 1462
Score = 152 bits (384), Expect = 3e-37, Method: Compositional matrix adjust.
Identities = 79/223 (35%), Positives = 124/223 (55%), Gaps = 26/223 (11%)
Frame = +1
Query: 326 HPHIVKLIGVITEN-PVWIIMELCTLGELRSFLQ-----VRKYS---------------- 363
H +IV +G T+ P+W+I+E G LR FL+ + Y
Sbjct: 127 HINIVNFLGCCTQGGPLWVIVEFAKNGNLRDFLESCRDGINGYGKFVSPQDPGWYTKTPG 306
Query: 364 ---LDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDS 420
+ +L+ YA+Q++ + +L S++ +HRD+AARNVLV+ +K+ DFGLSR
Sbjct: 307 GHVIRRKNLLSYAFQIARGMEFLASRKCIHRDLAARNVLVTEEHVLKIADFGLSR--TGD 480
Query: 421 TYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGR 480
Y K S G+LP+KWMAPE++ R+T+ SDVW FGV +WEI G P+ + N ++ +
Sbjct: 481 YYKKRSGGRLPVKWMAPEALFDMRYTTKSDVWSFGVVLWEIFSLGGMPYASIPNEELYSK 660
Query: 481 -IENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQL 522
+++ R+P P LY++M +CW PS RP F++L +
Sbjct: 661 LLDDAYRMPRPELASGNLYAIMERCWLNRPSDRPEFSQLVGHI 789
>07291
Length = 833
Score = 136 bits (342), Expect = 3e-32, Method: Compositional matrix adjust.
Identities = 61/161 (37%), Positives = 100/161 (62%), Gaps = 2/161 (1%)
Frame = +1
Query: 364 LDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYY 423
L + L+ + Q++ +AYL+ + VHR++AARN +V+ + ++L D+G++ + +YY
Sbjct: 40 LTVVQLLDFGRQIADGMAYLQEVKVVHRNLAARNCIVTEDGRLQLSDYGVTGSLFPQSYY 219
Query: 424 KA--SKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRI 481
A S + +KWMAPE+I+ F+S SDVW FGV +WE+L G+ P+ V+N+ ++ +
Sbjct: 220 TADDSPARDLVKWMAPETIDNFHFSSKSDVWAFGVVLWELLTRGITPYPDVENSSLLPYL 399
Query: 482 ENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQL 522
+ G R+ P P +Y +MT CW P +RP F EL QL
Sbjct: 400 KEGHRMKKPKQSPEPVYEMMTACWNESPEQRPDFAELNDQL 522
>14116
Length = 1017
Score = 131 bits (330), Expect = 6e-31, Method: Compositional matrix adjust.
Identities = 84/287 (29%), Positives = 140/287 (48%), Gaps = 19/287 (6%)
Frame = -1
Query: 198 EKQGMRTHAVSVSETDDYAEIID------------EEDTYTMPSTRDYEIQRERIELGRC 245
+ G RT+ + E +DY +D +ED + I RE + +G
Sbjct: 789 DSNGTRTYNLEARE-NDYFNRLDVQGAEAMPLLHIDEDMMKLIENESLLIDREFLTMGEE 613
Query: 246 IGEGQFGDVHQGIYMSPENPA-LAVAIKTCKNCTSDSVR-EKFLQEACHYTSLHWNWCRY 303
IG+G FG V +G PE + VA+KT N + + FLQEA
Sbjct: 612 IGKGNFGCVKRGFLTLPEQKGDILVAVKTLHNNNPREIELQSFLQEA------------- 472
Query: 304 ISDPNVDCPDPRNAEVTMRQFDHPHIVKLIGV---ITENPVWIIMELCTLGELRSFLQVR 360
+ M+ F H +++ LIG+ + + P+ +++ G+L ++++
Sbjct: 471 ---------------LIMKDFHHSNVLTLIGICLNLDDMPL-VVLPFMKHGDLLTYIRDD 340
Query: 361 KYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDS 420
++ + LI+Y ++ + YL +FVHRD+AARN ++ + VK+ DFGL+R + +
Sbjct: 339 QHQPTIKDLIMYGVDIARGMDYLAGLKFVHRDLAARNCMLDEDFHVKVADFGLARDIYEK 160
Query: 421 TYYKA--SKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHG 465
YY + K KLP+KWMA ES+ + S +DVW +GV +WE+L G
Sbjct: 159 EYYSSENKKAKLPVKWMALESLEKGNYDSKTDVWSYGVVLWELLTRG 19
>17300
Length = 480
Score = 123 bits (309), Expect(2) = 3e-30, Method: Compositional matrix adjust.
Identities = 56/117 (47%), Positives = 78/117 (66%), Gaps = 3/117 (2%)
Frame = +1
Query: 376 LSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDST---YYKASKGKLPI 432
+S+ + L +VHRD+AARN+LV+ K+ DFGLSR +E T Y GK+P+
Sbjct: 1 ISSGMGXLADMGYVHRDLAARNILVNEILVCKVADFGLSREIESDTTEGAYTTKGGKIPV 180
Query: 433 KWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPM 489
+W APE+I +R+FTSASDVW FGV MWE++ +G +P+ N DVI +E G RLP+
Sbjct: 181 RWTAPEAIAYRKFTSASDVWSFGVVMWEVMSYGERPYWNWSNQDVIKAVEKGYRLPL 351
Score = 26.9 bits (58), Expect(2) = 3e-30, Method: Composition-based stats.
Identities = 9/25 (36%), Positives = 14/25 (56%)
Frame = +2
Query: 492 NCPPTLYSLMTKCWAYDPSRRPRFT 516
+CP L+ LM W + S RP+ +
Sbjct: 356 DCPEALHQLMLDAWQKERSHRPKMS 430
>20640
Length = 1492
Score = 125 bits (313), Expect = 6e-29, Method: Compositional matrix adjust.
Identities = 55/136 (40%), Positives = 84/136 (61%), Gaps = 1/136 (0%)
Frame = +1
Query: 388 FVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASK-GKLPIKWMAPESINFRRFT 446
+VHRD+A RN LV + VK+ DFGL+R + YY+ S+ +PI+WM E+I + +F+
Sbjct: 7 YVHRDLATRNCLVGHDLVVKISDFGLARSVHSVDYYRGSEHDAIPIRWMPLEAILYNKFS 186
Query: 447 SASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWA 506
+ SDVW FGV +WEI ++P+ G+ + +V+ ++ G+ L P PP +Y LM +CW
Sbjct: 187 TQSDVWSFGVVLWEIFAFALQPYYGLTHEEVVRFVKEGKVLACPERTPPPMYELMKQCWH 366
Query: 507 YDPSRRPRFTELKAQL 522
P+ RP F L L
Sbjct: 367 RRPATRPSFHTLHKTL 414
>08294
Length = 1849
Score = 118 bits (296), Expect = 6e-27, Method: Compositional matrix adjust.
Identities = 67/210 (31%), Positives = 113/210 (53%), Gaps = 12/210 (5%)
Frame = +2
Query: 327 PHIVKLIGVITE-NPVWIIMELCTLGELRSFL-----------QVRKYSLDLASLILYAY 374
P+IV +GV E P ++I E C G+L+ FL R +L L+ +
Sbjct: 887 PNIVHFMGVCREAEPHFLITEYCDWGDLKQFLLATRNDNGRGRGTRVPALALSQKLGMGQ 1066
Query: 375 QLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKW 434
Q++ + L ++ VH D+AARNVL++S +K+ LS + S YY + +P++W
Sbjct: 1067 QVAAGMEALSNQGLVHGDLAARNVLLTSRMQLKVARPALSGDVYASEYYPLHQRLVPLRW 1246
Query: 435 MAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCP 494
+ PE + T+ DVW FGV +WE+L P++ + + +V+ +++ + P+ P
Sbjct: 1247 LPPEGVLEDSATTCGDVWAFGVFLWEVLQLADLPYRLMSDEEVLRSLQHSQAALDSPDAP 1426
Query: 495 PTLYSLMTKCWAYDPSRRPRFTELKAQLSF 524
P L SL+ +C A PS+RP F+E+ + LS
Sbjct: 1427 PALLSLLQRCTAQQPSQRPPFSEICSVLSL 1516
>07940
Length = 1336
Score = 118 bits (296), Expect = 6e-27, Method: Compositional matrix adjust.
Identities = 54/111 (48%), Positives = 77/111 (69%), Gaps = 1/111 (0%)
Frame = -3
Query: 369 LILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYY-KASK 427
LI YAYQ++ + YL SK+ +HRD+AARNVLV+ +K+ DFGL+R ++ YY K +
Sbjct: 341 LISYAYQVARGMEYLASKQCIHRDLAARNVLVAEEYVLKIADFGLTRNLQQFDYYRKTTD 162
Query: 428 GKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVI 478
G+LP+KWMAPE++ R++TS SDVW +GV +WEI G P+ V D+
Sbjct: 161 GRLPVKWMAPEALFDRKYTSKSDVWSYGVLLWEIFTLGGNPYPSVPVEDLF 9
Score = 46.6 bits (109), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 37/144 (25%), Positives = 60/144 (41%), Gaps = 3/144 (2%)
Frame = -3
Query: 221 EEDTYTMPSTRDYEIQRERIELGRCIGEGQFGDVHQGIYMS--PENPALAVAIKTCKNCT 278
E Y +P +E RER+ LG +GEG FG V +G M +N ++ VA+K K
Sbjct: 893 EVSEYDLPLDAKWEFPRERLVLGDRLGEGAFGLVMKGEAMGIFKDNNSVTVAVKMLKEDA 714
Query: 279 SDSVREKFLQEACHYTSLHWNWCRYISDPNVDCPDPRNAEVTMRQFDHPHIVKLIGVITE 338
+D ++E E+ H +I+ L+G T+
Sbjct: 713 TDREMMDLIRE---------------------------MEMMKVIGKHKNIINLLGCCTQ 615
Query: 339 -NPVWIIMELCTLGELRSFLQVRK 361
+++I+E G LR FL+ +
Sbjct: 614 RGALYVIVEFAPHGNLRDFLKSHR 543
>18996
Length = 491
Score = 110 bits (275), Expect = 2e-24, Method: Compositional matrix adjust.
Identities = 56/136 (41%), Positives = 82/136 (60%), Gaps = 6/136 (4%)
Frame = +2
Query: 389 VHRDIAARNVLVSSNDCVKLGDFGLSRYME-DSTYYKASKGKLPIKWMAPESINFRRFTS 447
+HRD+AARN+LV + CVK+ DFGL+++ D YY S+ +PIKW +PE+I +F+S
Sbjct: 2 IHRDLAARNILVDRS-CVKISDFGLAQFANADGYYYGISQRDIPIKWYSPEAIETCKFSS 178
Query: 448 ASDVWMFGVCMWEILMHG----VKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYS-LMT 502
SDVW +GV ++E+ G + P + + + R+ GERLP P C +YS LM
Sbjct: 179 YSDVWSYGVTLFEMFSRGEIPNLLPGHDLTQEEFLNRLRKGERLPKPELCSDFVYSELMR 358
Query: 503 KCWAYDPSRRPRFTEL 518
CW P RP F ++
Sbjct: 359 PCWHEMPKSRPTFHQI 406
>14477
Length = 493
Score = 95.1 bits (235), Expect = 6e-20, Method: Composition-based stats.
Identities = 64/197 (32%), Positives = 104/197 (52%), Gaps = 2/197 (1%)
Frame = -1
Query: 234 EIQRERIELGRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSD-SVREKFLQEACH 292
+IQ + ++LG G FG V +G+ ++ + VAIK KN D SV+ + ++EA
Sbjct: 490 QIQMDELKLG----AGNFGSVMKGV-CRLDDREIPVAIKVLKNADLDPSVQSELIKEA-- 332
Query: 293 YTSLHWNWCRYISDPNVDCPDPRNAEVTMRQFDHPHIVKLIGVITENPVWIIMELCTLGE 352
EV M++ DH HIV+LIG+ + +++EL LG
Sbjct: 331 -------------------------EV-MKKMDHMHIVRLIGLCEGETMMLVLELAKLGP 230
Query: 353 LRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFG 412
L FL K+ L L +++ +Q+S + YLE+ +FVHRD+AARN+L+ K+ DFG
Sbjct: 229 LNKFLPKNKH-LPLWNILELMWQVSQGMEYLEANKFVHRDLAARNILLCDEHFAKISDFG 53
Query: 413 LSRYM-EDSTYYKASKG 428
+S+ + ++ YY A +
Sbjct: 52 MSKTLSRENNYYMAQEA 2
>17637
Length = 447
Score = 90.1 bits (222), Expect = 2e-18, Method: Compositional matrix adjust.
Identities = 46/128 (35%), Positives = 70/128 (54%), Gaps = 1/128 (0%)
Frame = +1
Query: 397 NVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKL-PIKWMAPESINFRRFTSASDVWMFG 455
N ++ VKL D LSR + Y G+ PIKW++ E++ + SDVW FG
Sbjct: 1 NCVIDDQLRVKLTDSALSRDLFSGDYNCLGDGEYRPIKWLSLEALQKSHYNEGSDVWSFG 180
Query: 456 VCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRF 515
V MWE+ G P+ + ++ +++G RL P NCP L+++M CWA P+ RP F
Sbjct: 181 VLMWEMCTLGKLPYAEIDPYEMEHYLKDGYRLAQPFNCPDELFTIMAYCWASMPAERPSF 360
Query: 516 TELKAQLS 523
++L+ LS
Sbjct: 361 SQLQICLS 384
>22005
Length = 873
Score = 87.0 bits (214), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 61/187 (32%), Positives = 93/187 (49%), Gaps = 45/187 (24%)
Frame = +1
Query: 321 MRQFDHPHIVKLIGVIT-ENPVWIIMELCTLGELRSFLQV---RKYSL------------ 364
M FDHP+IVKL+GV P+ ++ E + G+L FL++ Y+L
Sbjct: 172 MADFDHPNIVKLLGVCAIGKPMCLLFEFMSKGDLNDFLRLCSPENYNLPVSRSQNLVVDL 351
Query: 365 ----------------------DLASLI-----LY-AYQLSTALAYLESKRFVHRDIAAR 396
D + ++ LY + Q+S +AYL K +VHRD+A R
Sbjct: 352 EDGLRVEVEAEECEKDTQSEDRDCSGMLXTKDQLYISQQISAGMAYLAQKDYVHRDLATR 531
Query: 397 NVLVSSNDCVKLGDFGLSRYMEDSTYYKAS-KGKLPIKWMAPESINFRRFTSASDVWMFG 455
V + + DFGL+R + YY+ S + +PI+WM E+I + +F++ SDVW FG
Sbjct: 532 TVXSRTT*-S*ISDFGLARSVHSVDYYRGSEQDAIPIRWMPLEAILYSKFSTQSDVWSFG 708
Query: 456 VCMWEIL 462
V +WEIL
Sbjct: 709 VVLWEIL 729
>18921
Length = 697
Score = 86.3 bits (212), Expect = 3e-17, Method: Compositional matrix adjust.
Identities = 56/181 (30%), Positives = 90/181 (49%), Gaps = 4/181 (2%)
Frame = +2
Query: 321 MRQFDHPHIVKLIGVITENP-VWIIMELCTLGELRSFLQVRKYSL---DLASLILYAYQL 376
M+Q D +IVK G +N +WI+ME C G + +++R +L ++A+++ Y +
Sbjct: 176 MQQCDSKYIVKYYGSYFKNTDLWIVMEYCGAGSVSDIMRLRNKTLVEREIATILYYTLK- 352
Query: 377 STALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMA 436
L YL S+R +HRDI A N+L+++ KL DFG++ + D+ + + P WMA
Sbjct: 353 --GLXYLHSRRKIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTPY-WMA 523
Query: 437 PESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPT 496
PE I + +D+W G+ E + G P I G+ P N PP
Sbjct: 524 PEVIQEIGYDCVADIWSLGITALE-MAEGKPPVMETS-------IL*GQSS*FPTNAPPP 679
Query: 497 L 497
L
Sbjct: 680 L 682
>17253
Length = 483
Score = 82.4 bits (202), Expect = 4e-16, Method: Composition-based stats.
Identities = 56/180 (31%), Positives = 88/180 (48%), Gaps = 14/180 (7%)
Frame = -1
Query: 269 VAIKTCKNCTSDSVREKFLQEACHYTSLHWNWCRYISDPNVDCPDPRNAEVTMRQFDHPH 328
VA+KT +D+ + +FL+E L PR HP+
Sbjct: 459 VAVKTHNEAATDAEKSEFLRELSIMRKL-----------------PR----------HPN 361
Query: 329 IVKLIGVIT-ENPVWIIMELCTLGELRSFLQVRK---------YSLDLASLILYAYQLST 378
+V +G T +P I+ME C G+L SFL+ R+ + DL + +++ L
Sbjct: 360 VVSFMGCCTMSDPALILMEFCCHGDLLSFLRKRRPDRTVFLTSTANDLTARDFFSFALHV 181
Query: 379 A--LAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDS--TYYKASKGKLPIKW 434
A +A++ + + VHRD+AARNVL+S + K+ DFGLSR + D Y S+ LP++W
Sbjct: 180 ARGMAHVANNKIVHRDVAARNVLISERNVCKVSDFGLSRRVGDQNDVYEIVSRRPLPLRW 1
>13305
Length = 549
Score = 82.0 bits (201), Expect = 5e-16, Method: Compositional matrix adjust.
Identities = 36/94 (38%), Positives = 53/94 (56%)
Frame = +2
Query: 429 KLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLP 488
++PI+WMA ES+ +T+ SDVW FGV +WEI G P+ + +++G RL
Sbjct: 8 RVPIRWMAVESLFNNTYTTQSDVWSFGVVLWEIFTLGGTPYSSTDTQQLFAFLKDGYRLK 187
Query: 489 MPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQL 522
P C Y++M +CW + RRP F EL +L
Sbjct: 188 RPKLCDQNTYAMMLQCWNENAQRRPTFPELCGRL 289
>01718
Length = 959
Score = 79.3 bits (194), Expect = 4e-15, Method: Compositional matrix adjust.
Identities = 59/212 (27%), Positives = 90/212 (42%), Gaps = 14/212 (6%)
Frame = +3
Query: 321 MRQFDHPHIVKLIGV-ITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTA 379
+ + H +I++ +GV + E + + E G L L+ + L I L+
Sbjct: 294 LNRLQHANILRFMGVCVHEGQLHALTEYIPSGNLEQLLEKKDEELPWTQRIQLTLGLARG 473
Query: 380 LAYLESKRFVHRDIAARNVLVSSND----CVKLGDFGLSRYMEDSTYYKASKGKLPI--- 432
L YL S RF+HRD+ ++N+L+ D + DFGL+ + D K KLP
Sbjct: 474 LDYLHSTRFIHRDLTSKNILIRREDNHGYHAVIADFGLATKIPDPL----DKEKLPTVGS 641
Query: 433 -KWMAPESINFRRFTSASDVWMFGVCMWEILMH-----GVKPFQGVKNNDVIGRIENGER 486
WMAPE +N + +D++ G+ M EI + P D + E
Sbjct: 642 PYWMAPEVLNGHFYNERADLFSVGIIMCEITARIPADPDIMPRMNNFGVDYVALSE---- 809
Query: 487 LPMPPNCPPTLYSLMTKCWAYDPSRRPRFTEL 518
M CP L KC DP +RPR E+
Sbjct: 810 --MISYCPLDYLQLAFKCCQVDPQKRPRGVEI 899
>00300
Length = 2318
Score = 78.2 bits (191), Expect = 8e-15, Method: Compositional matrix adjust.
Identities = 74/302 (24%), Positives = 124/302 (41%), Gaps = 11/302 (3%)
Frame = -1
Query: 228 PSTRDYEIQRERIEL----GRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVR 283
P DY I R+ G IGEGQFG V+ + MS +A+K K +D +
Sbjct: 1700 PREPDYRINVRRVNFRWQRGNKIGEGQFGKVYTAVNMST---GELMALKEMKFQPNDLQQ 1530
Query: 284 EKFLQEACHYTSLHWNWCRYISDPNVDCPDPRNAEVTMRQFDHPHIVKLIGV-ITENPVW 342
L+E C + H ++VK GV + ++ +
Sbjct: 1529 ---LREMCDEIKI------------------------FEGIQHENLVKYYGVEVHKDEML 1431
Query: 343 IIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSS 402
+ ME C G + + K L + Y ++ A+ +L VHRDI N+ ++S
Sbjct: 1430 MFMEYCDTGTIE---EAAKMGLPEYLIRRYTREIVLAVNHLHENSIVHRDIKGANIFLTS 1260
Query: 403 NDCVKLGDFGLSRYMEDSTYYKASKGKL--PIKWMAPESINFRR---FTSASDVWMFGVC 457
N VKLGDFG S ++ T L +MAPE + A+D+W G
Sbjct: 1259 NGHVKLGDFGCSVKLKSHTTMPGEFHNLVGTTAYMAPEVFTQNDQGGYGRAADIWSLGCV 1080
Query: 458 MWEILMHGVKPFQGVKNN-DVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFT 516
+ E+ G +P+ + NN ++ ++ G + +P + + +DP++R +
Sbjct: 1079 VIEMAT-GKRPWHDLDNNYQIMYKVGIGHKPAVPDSLSVEGKHFLDLIMCHDPAQRALAS 903
Query: 517 EL 518
+L
Sbjct: 902 QL 897
>19301
Length = 712
Score = 74.7 bits (182), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 37/95 (38%), Positives = 61/95 (64%), Gaps = 1/95 (1%)
Frame = +2
Query: 321 MRQFDHPHIVKLIGVITENPVW-IIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTA 379
+R+ +HP+I+ GV T+ P + IIME C G+L L+ K + A ++ ++ Q+++
Sbjct: 431 LRKLNHPNIISFKGVCTQAPCYCIIMEYCPYGQLYEVLRDGK-EIPPALVLDWSKQIASG 607
Query: 380 LAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLS 414
+ YL S + +HRD+ + NVLV+ ND VK+ DFG S
Sbjct: 608 MNYLHSHKIIHRDLKSPNVLVAKNDVVKISDFGTS 712
>12721
Length = 821
Score = 74.3 bits (181), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 55/205 (26%), Positives = 88/205 (42%), Gaps = 8/205 (3%)
Frame = +1
Query: 316 NAEVTMRQFDHPHIVKLIG-VITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAY 374
N V MR + HP+IV++ + + +W++ME G L V +D +
Sbjct: 223 NEVVVMRDYHHPNIVEMYNSYLVNDELWVVMEFMEGGALTDI--VTNNRMDEVQIATVCR 396
Query: 375 QLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKW 434
ALA+L + +HRDI + ++L+S + VKL DFG + + S P W
Sbjct: 397 ACLKALAFLHANGVIHRDIKSDSILLSHDGKVKLXDFGFCAQVTQDLQKRKSLVGTPY-W 573
Query: 435 MAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPP--- 491
MAPE I+ + D+W G+ + E ++ PF + RI + MPP
Sbjct: 574 MAPEVISRLPYGPEVDIWSLGIMVME-MIDAEPPFFNEPPLQAMRRIRD-----MPPPKL 735
Query: 492 ----NCPPTLYSLMTKCWAYDPSRR 512
P L + + DP +R
Sbjct: 736 RNTHKISPRLQGFIDRMLVRDPHQR 810
>14420
Length = 528
Score = 69.7 bits (169), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 42/155 (27%), Positives = 73/155 (47%), Gaps = 1/155 (0%)
Frame = +2
Query: 316 NAEVTMRQFDHPHIVK-LIGVITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAY 374
N + MR+ +P+IV L + +W++ME G L V + +D +
Sbjct: 47 NEILVMRENQNPNIVNYLDSYLVGEELWVVMEFLAGGSLTDV--VTETCMDEGQIAAVCR 220
Query: 375 QLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKW 434
+ AL +L + +HRDI + N+L+ + VKL DFG + +++ P W
Sbjct: 221 ECLQALEFLHENQVIHRDIKSDNILLGMDGSVKLTDFGFCAQLSPEQSKRSTMVGTP-YW 397
Query: 435 MAPESINFRRFTSASDVWMFGVCMWEILMHGVKPF 469
MAPE + +++ D+W GV E ++ G P+
Sbjct: 398 MAPEVVTRKQYGPTVDIWSLGVMCIE-MIEGEPPY 499
>30755
Length = 1137
Score = 69.3 bits (168), Expect = 4e-12, Method: Compositional matrix adjust.
Identities = 44/143 (30%), Positives = 76/143 (53%), Gaps = 1/143 (0%)
Frame = +2
Query: 371 LYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKL 430
Y ++ +AL YL S+ ++RD+ N+L+ + +K+ DFGL + ED TY + +K
Sbjct: 44 FYGAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCK--EDITYGRTTKTFC 217
Query: 431 PI-KWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPM 489
+++APE ++ + A D W GV M+E++ G PF +++DV+ + E +
Sbjct: 218 GTPEYLAPEVLDDNDYGRAVDWWGTGVVMYEMIC-GRLPFYN-RDHDVLFTLILVEDVKF 391
Query: 490 PPNCPPTLYSLMTKCWAYDPSRR 512
P N SL++ A DP R
Sbjct: 392 PRNITDEAKSLLSGLLAKDPRNR 460
>27546
Length = 426
Score = 69.3 bits (168), Expect = 4e-12, Method: Composition-based stats.
Identities = 35/108 (32%), Positives = 61/108 (56%), Gaps = 1/108 (0%)
Frame = -1
Query: 314 PRNAEVTMRQFDHPHIVKLIGVITENP-VWIIMELCTLGELRSFLQVRKYSLDLASLILY 372
PR E+ R DHP+I+++ ++ P ++I M G++ S ++ + +D A ++
Sbjct: 336 PRELEILTR-LDHPNIIQIHSILQRGPKIFIFMRYAEKGDMLSHIK-KTGPIDEAQTKVW 163
Query: 373 AYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDS 420
+Q++ AL YL S HRD+ N+L+S VK+ DFG +RY D+
Sbjct: 162 FFQMAKALQYLHSHDIAHRDLKCENILLSKRLNVKIADFGFARYCRDA 19
>13592
Length = 980
Score = 69.3 bits (168), Expect = 4e-12, Method: Compositional matrix adjust.
Identities = 55/209 (26%), Positives = 97/209 (46%), Gaps = 8/209 (3%)
Frame = +2
Query: 321 MRQFDHPHIVKLIGV-ITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTA 379
+ H ++V+ G+ + + I MELC+ G L S +++ L A + QL +
Sbjct: 143 LEGIKHKNLVRYYGIEVHREELLIFMELCSEGTLESLVELTG-GLPEALSRRFTAQLLSG 319
Query: 380 LAYLESKRFVHRDIAARNV-LVSSNDCVKLGDFGLSRYMEDSTYYKAS-KGKLPIK-WMA 436
+A L VHRDI N+ LV ++ +KLGDFG + ++ T +G + + +MA
Sbjct: 320 VAELHKHGIVHRDIKTANIFLVDGSNSLKLGDFGSAVKIQAHTTVPGELQGYVGTQAYMA 499
Query: 437 PE---SINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNN-DVIGRIENGERLPMPPN 492
PE N +D+W G + E + G +P+ +N ++ ++ GE+ P +
Sbjct: 500 PEVFTKTNSDGHGRLADIWSVGCVVVE-MASGKRPWAQFDSNFQIMFKVGMGEKPQAPES 676
Query: 493 CPPTLYSLMTKCWAYDPSRRPRFTELKAQ 521
+ + C +DP +R EL Q
Sbjct: 677 LSQEGHDFIDHCLQHDPKQRLSAIELLEQ 763
>31885
Length = 529
Score = 67.0 bits (162), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 46/148 (31%), Positives = 77/148 (52%), Gaps = 6/148 (4%)
Frame = -2
Query: 321 MRQFDHPHIVKL-IGVITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTA 379
+ + DHP +V L E ++++++L G+LR +Q ++ S + Y QL+
Sbjct: 510 LTRLDHPFLVNLWYAFQDEEDLFMVVDLFLGGDLRYHMQ-QEVSFREDCVKFYLCQLALV 334
Query: 380 LAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPE- 438
L YL S++ VHRDI N+L+ + DF ++ +ED ++ G P +MAPE
Sbjct: 333 LDYLRSQKIVHRDIKPDNILLDEQGHCHVTDFNIATQLEDDELATSTSGTRP--YMAPEV 160
Query: 439 ---SINFRR-FTSASDVWMFGVCMWEIL 462
+IN RR + D W GV ++E+L
Sbjct: 159 YGVAINERRGYGFPVDWWSLGVSLFELL 76
>09606
Length = 1300
Score = 65.1 bits (157), Expect = 8e-11, Method: Compositional matrix adjust.
Identities = 60/246 (24%), Positives = 99/246 (40%), Gaps = 31/246 (12%)
Frame = -3
Query: 312 PDPRNAEVTMRQFDHPHIVKLIGVI-TENPVWIIMELCTLGELRSFLQVRKYSLDLASLI 370
P+ N HP++V+ T N +W+++ELCT G L L + + L S+
Sbjct: 998 PEVTNTVRMTHDISHPNVVQFHEWYETSNHLWLVVELCTGGSLADIL-AQDHHLPETSIR 822
Query: 371 LYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRY----MEDSTYYKAS 426
+ L T L Y+ S + D+ VL+ ++ +K DFGLS+ +E+ + A
Sbjct: 821 DFGIHLVTGLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAE 642
Query: 427 KG-------------KLPIK----WMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPF 469
G ++P +MAPE + SD+W G +E + G PF
Sbjct: 641 AGDQWNIQSAEEMMKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYE-MFSGHPPF 465
Query: 470 QGVKNNDVIGRIEN---------GERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKA 520
G + ++ N G RL P+ P +L+ D +RR + L
Sbjct: 464 LGETYDITKDKVLNKEFPLPKVKGSRLSAKPS--PEFLNLLESLLQKDSTRRLSWASLVK 291
Query: 521 QLSFQN 526
+Q
Sbjct: 290 HAFWQG 273
>13066
Length = 551
Score = 63.9 bits (154), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 43/152 (28%), Positives = 75/152 (49%), Gaps = 10/152 (6%)
Frame = +3
Query: 314 PRNAEVTMRQFDHPHIVKLIGVITENPV-WIIMELCTLGELRSFLQVRKYSLDLASLILY 372
PR ++ + + DHP+I+++ ++ P +I M G+L +++Q + + + I +
Sbjct: 120 PRELDL-LTKLDHPYIIQIHSILQRXPKNFIFMRFAERGDLLTYIQEVGFVKEKQAKIWF 296
Query: 373 AYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLS---------RYMEDSTYY 423
YQ++TAL YL S HRD+ N+L+SS+ VKL DFG + +YM +
Sbjct: 297 -YQMTTALNYLHSYDVAHRDLKCENILLSSHFNVKLADFGFACACITESGEKYMSRTYCG 473
Query: 424 KASKGKLPIKWMAPESINFRRFTSASDVWMFG 455
A+ I + AP + +D W G
Sbjct: 474 SAAYAAPEIVYGAPYA------PKVADAWSLG 551
>07833
Length = 1504
Score = 63.2 bits (152), Expect = 3e-10, Method: Compositional matrix adjust.
Identities = 51/202 (25%), Positives = 93/202 (46%), Gaps = 7/202 (3%)
Frame = -3
Query: 321 MRQFDHPHIVKLIGVITENP-VWIIMELCTLGELRSFLQVRK-YSLDLASLILYAYQLST 378
+R F+HP+++ ++ + P + +I + G L + L +D + +A ++
Sbjct: 1457 LRIFNHPNVLPVLACCNQPPNLVLISQFMPFGSLYNTLHGESGIVVDQNQSLRFAMDIAR 1278
Query: 379 ALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKL-PIKWMAP 437
+ +L S + N L++S + D M D + KGK+ WMAP
Sbjct: 1277 GMEFLHSM-----EPTIPNFLLTSKHVMIDEDLTARINMADYCFSFHEKGKVYSPAWMAP 1113
Query: 438 ESINFRR---FTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIE-NGERLPMPPNC 493
E++ R T A+D+W F + MWE+ V PF + + +V ++ G R+ +PP
Sbjct: 1112 EALQRRPDDINTRAADMWSFAILMWELETREV-PFAELSSMEVGMKVALEGLRISIPPGI 936
Query: 494 PPTLYSLMTKCWAYDPSRRPRF 515
+ L+ C +P +RPRF
Sbjct: 935 SLHMSRLIKICMNEEPGKRPRF 870
>00715
Length = 1788
Score = 62.8 bits (151), Expect = 4e-10, Method: Compositional matrix adjust.
Identities = 52/221 (23%), Positives = 96/221 (43%), Gaps = 33/221 (14%)
Frame = +1
Query: 326 HPHIVKLIGVIT----ENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALA 381
H ++V ++G + E+ W+ ME L++ L + +D + + A Q++ L
Sbjct: 103 HVNVVSILGATSLHRFEDGAWLAMEYVGPLNLQTILNDHQQDIDSSMRLSLALQMARGLH 282
Query: 382 YLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYM-------------------EDSTY 422
YL S VH D+ N L++ + +++ DFG + E +
Sbjct: 283 YLHSINIVHLDLKPANCLLTRDLKLRIADFGCCHQLTPTGLDMGEREGGMAGNELELTPV 462
Query: 423 YKASKGKLP--IKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGR 480
A K +L + + APE + + + SDV+ G+ +W++ P++GV + V+ +
Sbjct: 463 QGAWKNELAGTLAYRAPELLKGLQPSVRSDVYSLGITLWQMCTRQ-GPYEGVPAHAVVYQ 639
Query: 481 IENGERLPMPPNCPPT--------LYSLMTKCWAYDPSRRP 513
+ + + P PP P T L T+CWA RP
Sbjct: 640 VVSKDLRPCPP--PSTEDDPFEVMFRDLYTQCWARRVEDRP 756
>19094
Length = 898
Score = 62.0 bits (149), Expect = 6e-10, Method: Compositional matrix adjust.
Identities = 34/114 (29%), Positives = 62/114 (54%), Gaps = 3/114 (2%)
Frame = +1
Query: 351 GELRSFLQVRKYSL---DLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVK 407
G + +++R +L ++A+++ Y + L YL S+R +HRDI A N+L+++ K
Sbjct: 10 GSVSDIMRLRNKTLVEREIATILYYTLK---GL*YLHSRRKIHRDIKAGNILLNNEGHAK 180
Query: 408 LGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEI 461
L DFG++ + D+ + + P WMAPE I + +D+W G+ E+
Sbjct: 181 LADFGVAGQLTDTMAKRNTVIGTPY-WMAPEVIQEIGYDCVADIWSLGITALEM 339
>13212
Length = 1067
Score = 61.2 bits (147), Expect = 9e-10, Method: Compositional matrix adjust.
Identities = 51/196 (26%), Positives = 84/196 (42%), Gaps = 18/196 (9%)
Frame = -1
Query: 341 VWIIMELCTL---GELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARN 397
VW I+++ + G L S + + + A + +++ AL +L +HRDI A N
Sbjct: 1067 VWXIVDVFRVLWWGALDSIMVDLEKPMTEAQICYVCHEMCMALDFLHRHHVIHRDIKAGN 888
Query: 398 VLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAP-----ESINFRRFTSASDVW 452
VL++ + VKL DFG+S + + + P WMAP E++ + +D+W
Sbjct: 887 VLLTIDGEVKLADFGVSAKNTQTQQKRDTFIGTPY-WMAPEVVLCETLKDTPYDFKADIW 711
Query: 453 MFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTL----------YSLMT 502
GV + E P + + V+ +I + PPTL +
Sbjct: 710 SLGVTLIE-FAQIEPPNKEMHPMRVLIKIHKSD--------PPTLEKPKKWTKLFKDFIA 558
Query: 503 KCWAYDPSRRPRFTEL 518
KC DP+ RP EL
Sbjct: 557 KCLVKDPNLRPTAAEL 510
>29581
Length = 1278
Score = 59.3 bits (142), Expect = 4e-09, Method: Compositional matrix adjust.
Identities = 43/147 (29%), Positives = 71/147 (48%), Gaps = 8/147 (5%)
Frame = -2
Query: 326 HPHIVKLIGVI---TENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAY 382
H +IV+L V+ + + ++++ME C +L S L + + QL L Y
Sbjct: 1178 HQNIVQLQEVVVGKSLDSLFLVMEYCE-QDLASLLDNMPAPFSESQVKCIVLQLLKGLRY 1002
Query: 383 LESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLP----IKWMAPE 438
L +HRD+ N+L++ CVK+ DFGL+R Y K K P + + APE
Sbjct: 1001 LHEAFIIHRDLKVSNLLMTDKGCVKIADFGLAR-----NYGKPQKPMTPKVVTLWYRAPE 837
Query: 439 SI-NFRRFTSASDVWMFGVCMWEILMH 464
+ + ++A D+W G + E+L H
Sbjct: 836 LLFGSKTHSTAIDMWSAGCILGELLGH 756
>19761
Length = 473
Score = 58.9 bits (141), Expect = 5e-09, Method: Compositional matrix adjust.
Identities = 34/130 (26%), Positives = 67/130 (51%), Gaps = 8/130 (6%)
Frame = -3
Query: 369 LILYAYQLSTALAYLESKR--FVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKAS 426
++ + Q ++AL Y+ + +HRD+ +N+ V+ V+LGD GL+R + + S
Sbjct: 417 IVCWLMQTASALNYMHTHTPVILHRDLKPQNIYVTEKGDVRLGDLGLARKLTGPADFATS 238
Query: 427 KGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIG------R 480
+ I +++PE ++ + + S SD+W G ++I G K +D +G +
Sbjct: 237 QVG-TIMYLSPEILSQQPYNSKSDIWSLGCVFYDI--------TGKKGSDEMGVMFLLVQ 85
Query: 481 IENGERLPMP 490
+ G +LP+P
Sbjct: 84 VMGGRKLPLP 55
>14126
Length = 1265
Score = 57.8 bits (138), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 48/185 (25%), Positives = 87/185 (47%), Gaps = 14/185 (7%)
Frame = +3
Query: 321 MRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVRKYSLDLASLIL--------- 371
+ Q++HP++V+L+ V + N + T E+R L DLA+ +
Sbjct: 360 LEQYEHPNVVRLLDV-SHNTI-------TDREIRLNLVFEYIEHDLATYLAKCPSPGLGP 515
Query: 372 -----YAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKAS 426
QL + +L S R VHRD+ +N+L+S + +KL DFGL+R S + +
Sbjct: 516 DRIKDLMLQLLNGVDFLHSNRIVHRDLKPQNLLISKDGRLKLADFGLARIY--SFHMALT 689
Query: 427 KGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGER 486
+ + + +PE + + ++ D+W G C++ L F+G D + +I E
Sbjct: 690 TVVVTLWYRSPEVLMQAEYGTSVDIWSCG-CIFAELFTRRALFKGSSEFDQLKKI--FEV 860
Query: 487 LPMPP 491
+ +PP
Sbjct: 861 IGLPP 875
>04591
Length = 1117
Score = 56.6 bits (135), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 44/161 (27%), Positives = 72/161 (44%), Gaps = 16/161 (9%)
Frame = -2
Query: 321 MRQFDHPHIVKLIGVIT---------ENPVWIIMELCTLGELRSFLQVRKYSLDLASLIL 371
++Q +H ++V+L + ++ ++I E C +L L + LA
Sbjct: 1059 LQQLEHENVVQLQEICHTQAGPYNRYKSTFYLIFEYCDY-DLAGLLNNLRVKFSLADKKN 883
Query: 372 YAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLP 431
QL L Y+ +K+ +HRDI A N+L++ + +KL DFGLSR S K ++
Sbjct: 882 LMSQLLNGLFYIHTKQILHRDIKAANILLTRDGVLKLADFGLSRPWVKS---KRLTNRVV 712
Query: 432 IKWMAPESINF--RRFTSASDVWMFGVCMWEI-----LMHG 465
W P + R + D+W G M E+ LM G
Sbjct: 711 TLWYRPPELLLGEREYGPEIDMWGVGCIMAEMWSRKPLMQG 589
>21079
Length = 878
Score = 56.6 bits (135), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 34/128 (26%), Positives = 66/128 (51%), Gaps = 2/128 (1%)
Frame = +1
Query: 343 IIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSS 402
++ME GEL + + L + + Q+ + + Y+ ++ +H D+ NVL S
Sbjct: 55 LVMEFVGAGELFERVIRDDFVLTERDCVHFVRQICSGVGYMHTQSILHLDLKPENVLCVS 234
Query: 403 NDC--VKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWE 460
++ +K+ DFGL+R+ + + G P +++APE +N+ +D+W GV +
Sbjct: 235 DNSNQIKIIDFGLARFYKPGDSLQVLFGT-P-EFIAPEVVNYDEINFTTDMWSIGVICY- 405
Query: 461 ILMHGVKP 468
IL+ G+ P
Sbjct: 406 ILLSGLSP 429
>01060
Length = 1800
Score = 55.8 bits (133), Expect = 4e-08, Method: Compositional matrix adjust.
Identities = 37/148 (25%), Positives = 78/148 (52%), Gaps = 5/148 (3%)
Frame = +1
Query: 321 MRQFDHPHIVKLIGVITENP-VWIIMELCTLGELRSFLQV--RKYSLDLASLILYAYQLS 377
+R+ H +IV L VI E+ ++++ E ++ +L+ ++ LD + Y +Q+
Sbjct: 232 LRELRHTNIVCLEDVIMEDERLFLVFEFLSM-DLKMYIDKFPEGVVLDRRLVKSYVFQIV 408
Query: 378 TALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWM-A 436
T + + +R VHRD+ +N+L++ +K+ DFG++R + +A ++ W A
Sbjct: 409 TGIXFCHQRRIVHRDLKPQNLLINHTGAIKIADFGMARTF--ALPVRAYTHEVVTLWYRA 582
Query: 437 PESI-NFRRFTSASDVWMFGVCMWEILM 463
PE + ++++ DVW G ++L+
Sbjct: 583 PEILMGASKYSTPVDVWSIGTIFADMLI 666
>07836
Length = 1478
Score = 55.5 bits (132), Expect = 5e-08, Method: Compositional matrix adjust.
Identities = 62/243 (25%), Positives = 102/243 (41%), Gaps = 45/243 (18%)
Frame = -1
Query: 351 GELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRF--------VHRDIAARNVLVSS 402
G L +L R LD + ++ A+ LA+L + F HRDI ++N+LV
Sbjct: 1298 GSLHDYLLSR--VLDSSEMLALAHSAICGLAHLHIEIFGTRGKPAIAHRDIKSKNILVKK 1125
Query: 403 NDCVKLGDFGLS-RYMEDSTYYKASKG--KLPIKWMAPESI-------NFRRFTSASDVW 452
N + D GL+ RY+ +S + + ++MAPE + NF F A D++
Sbjct: 1124 NGTCCIADLGLAVRYISESNEVDVAPNPRQGTKRYMAPEVLEMLLNVKNFDAFKQA-DMY 948
Query: 453 MFGVCMWEI----LMHGVK-----PFQGVKNND--------VIGRIENGERLPMPPNCPP 495
FG+ MWEI ++ GV PF +D V+ + +P+ P
Sbjct: 947 AFGLVMWEIARCCVIGGVAEEYQVPFYNCLPHDPSFEDVRLVVSVDKVRPDIPLRWQEDP 768
Query: 496 ---TLYSLMTKCWAYDPSRRPRFTELKAQLSFQNPAQMLPASG-------RLPNQPCPER 545
+ +M +CW+ +P+ R +K L + Q SG +Q C E+
Sbjct: 767 IMKVMVKVMCECWSGNPAARLTALRVKKTLGKLSELQATKLSGIKS*SSTSTDHQCCQEK 588
Query: 546 ENY 548
+ Y
Sbjct: 587 KFY 579
>18484
Length = 635
Score = 55.5 bits (132), Expect = 6e-08, Method: Compositional matrix adjust.
Identities = 33/142 (23%), Positives = 68/142 (47%)
Frame = +1
Query: 371 LYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKL 430
YA +++ L +L + ++RD+ NV++ S +K+ DFG+ + +
Sbjct: 55 FYAAEIAVGLFFLHDQGIIYRDLKLDNVMLDSEGHIKIADFGMCKEGMTGDATTRTFCGT 234
Query: 431 PIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMP 490
P ++APE + ++ ++ + D W +GV ++E+L G PF G +++ I + + P
Sbjct: 235 P-DYIAPEIVLYQPYSKSVDWWAYGVLLFEMLA-GQPPFDGEDEDELFSSITD-HNVSYP 405
Query: 491 PNCPPTLYSLMTKCWAYDPSRR 512
SL +P++R
Sbjct: 406 KAMSREAVSLCKGLLMKNPTKR 471
>03240
Length = 1683
Score = 53.5 bits (127), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 49/190 (25%), Positives = 80/190 (42%), Gaps = 45/190 (23%)
Frame = -3
Query: 325 DHPHIVKLIGVITE-NPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYL 383
D+ +VKL + N ++ +M+ G+L L +R LD Y +L A+ +
Sbjct: 1117 DNEWVVKLYYSFQDHNYLYFVMDYVPGGDLMGLL-IRMEILDEPLARFYVAELVQAIESV 941
Query: 384 ESKRFVHRDIAARNVLVSSNDCVKLGDFGLS---RYMEDSTYYK-----ASKGKLPIK-- 433
F+HRDI N+L+ N +KL DFGL R+ +S YY+ A + + +K
Sbjct: 940 HRMGFIHRDIKPDNILIDRNGHIKLTDFGLCTGFRWTHNSKYYQRDGTHARQDSMEVKCQ 761
Query: 434 ---------------------------------WMAPESIN-FRRFTSASDVWMFGVCMW 459
++APE ++ +TS D W GV ++
Sbjct: 760 LDEQCQCEILKPLERRRKREQRCLAHSLVGTPNYIAPEVLSRLGGYTSVCDWWSVGVILF 581
Query: 460 EILMHGVKPF 469
E+L+ G PF
Sbjct: 580 EMLV-GHPPF 554
>26711
Length = 405
Score = 51.6 bits (122), Expect = 9e-07, Method: Composition-based stats.
Identities = 32/102 (31%), Positives = 58/102 (56%), Gaps = 5/102 (4%)
Frame = -2
Query: 375 QLSTALAYLESKRFVHRDIAARNVLVSSN--DCVKLGDFGLSRYM---EDSTYYKASKGK 429
Q+ L ++ ++ VH D+ N+L+S + D V+L DFGL+R + +++ + G
Sbjct: 392 QVLDILQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARKLYPPQETFLNHGTPG- 216
Query: 430 LPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQG 471
+ +PE+++ + ++ASDVW GV + IL+ G PFQ
Sbjct: 215 ----FTSPEALDVKPISTASDVWGVGVLAY-ILLSGQSPFQA 105
>15910
Length = 1361
Score = 50.8 bits (120), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 34/110 (30%), Positives = 56/110 (50%), Gaps = 3/110 (2%)
Frame = +2
Query: 379 ALAYLESKRFVHRDIAARNVL---VSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWM 435
+ Y+ + VHRD+ N+L ++ + +KL DFGLSR +E G P +
Sbjct: 500 GVQYIHANGVVHRDLKPENLLYECMTDDSKLKLADFGLSRIIEPEVQMSTVCGT-P-GYC 673
Query: 436 APESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGE 485
APE + ++T + D+W GV + IL+ G +PF ++ +I GE
Sbjct: 674 APEVLKGDKYTPSVDMWSVGVIAY-ILLCGYEPFFAENEFEMYRKIIKGE 820
>01756
Length = 1858
Score = 50.8 bits (120), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 35/153 (22%), Positives = 68/153 (44%), Gaps = 12/153 (7%)
Frame = -3
Query: 321 MRQFDHPHIVKLIGVIT---------ENPVWIIMELCTLGELRSFLQVRKYSLDLASLIL 371
++ +H ++V LI + + ++ +++ E C +L L +L +
Sbjct: 1583 LQLLNHENVVDLIEICSTKATSANRYKSMFYLVFEFCE-HDLAGLLSNMSVVFNLPEIKE 1407
Query: 372 YAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSR-YMEDSTYYKASKGKL 430
QL L Y+ + +HRD+ A N+L++ +KL DFGL+R + + ++
Sbjct: 1406 VMKQLMNGLYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRV 1227
Query: 431 PIKWMAPESINF--RRFTSASDVWMFGVCMWEI 461
W P + R +++A D W G M E+
Sbjct: 1226 VTLWYRPPELLLGDRNYSTAIDQWGAGCIMAEM 1128
>01966
Length = 1735
Score = 50.8 bits (120), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 27/98 (27%), Positives = 56/98 (57%), Gaps = 3/98 (3%)
Frame = -1
Query: 321 MRQFDHPHIVKLIGVITENP-VWIIMELCTLGELRSFLQV--RKYSLDLASLILYAYQLS 377
+R+ H +IV L VI E+ ++++ E ++ +L+ ++ LD + Y +Q+
Sbjct: 1552 LRELRHTNIVCLEDVIMEDERLFLVFEFLSM-DLKMYIDKFPEGVVLDRRLVKSYVFQIV 1376
Query: 378 TALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSR 415
T + + +R VHRD+ +N+L++ +K+ DFG++R
Sbjct: 1375 TGINFCHQRRIVHRDLKPQNLLINHTGAIKIADFGMAR 1262
>12672
Length = 773
Score = 49.3 bits (116), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 38/162 (23%), Positives = 69/162 (42%), Gaps = 16/162 (9%)
Frame = +3
Query: 377 STALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGL---SRYMEDSTYYKASKGKLPIK 433
++ + YL VHRDI N+L+ S K+GDF + E T AS
Sbjct: 21 ASGIQYLNDNGHVHRDIKTANILLDSEYTAKVGDFATVVSAPSGEGKTVQNASVVIGTAA 200
Query: 434 WMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPF----QGVKNNDVIGRIENGERL-- 487
++APE+I+F ++ D + FGV + E++ V + ++ ++ +E E +
Sbjct: 201 YLAPEAIHF-DVSTKLDSYSFGVVLLEVITGLVAQDYSREERTLSSHIMENVEEPEEIHD 377
Query: 488 -------PMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQL 522
P LY + +C +RP +++ +L
Sbjct: 378 FVDQSAGTWPDGAVDKLYDISMRCLNLSKKQRPNVKDIRPEL 503
>25550
Length = 941
Score = 48.1 bits (113), Expect = 9e-06, Method: Compositional matrix adjust.
Identities = 33/120 (27%), Positives = 54/120 (45%), Gaps = 21/120 (17%)
Frame = +3
Query: 454 FGVC-MWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRR 512
G C +W++ + GV +V +E G R+ P P +Y LM KCW +DP R
Sbjct: 12 MGACDIWDVX------YPGVDLTEVYHLLERGYRMERPQGTPADVYILMLKCWQWDPKER 173
Query: 513 PRFTEL---------KAQLSFQ-------NPAQMLPA----SGRLPNQPCPERENYSFAT 552
P F E+ K+ +S + N +++P GR+PN P+ ++ A+
Sbjct: 174 PTFKEIHYLLENMFEKSSISEEVEKELEKNDKKLIPTLPSKKGRVPNTDSPDFQSEGRAS 353
>21433
Length = 590
Score = 48.1 bits (113), Expect = 9e-06, Method: Compositional matrix adjust.
Identities = 30/98 (30%), Positives = 49/98 (50%)
Frame = +2
Query: 372 YAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLP 431
Y YQLS+AL Y ++ +HRDI N+L+ +K+ DFG S + S + +
Sbjct: 182 YIYQLSSALEYCHYRKVIHRDIKPENLLLGLKGDLKIADFGWSVHAPSS---RRTTMCGT 352
Query: 432 IKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPF 469
+ ++ PE + + D+W GV +E L+ G P
Sbjct: 353 LDYLPPEMVEGKTHDENVDLWSLGVLCYEFLV-GTPPL 463
>01707
Length = 757
Score = 47.0 bits (110), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 44/165 (26%), Positives = 73/165 (44%), Gaps = 15/165 (9%)
Frame = +1
Query: 313 DPRNAEVTMR------QFDHPHIVKLIGVITENP----VWIIMELCTLGELRSFLQVRKY 362
DP ++ MR Q HP++V+LI V V+ ++ L EL + R
Sbjct: 181 DPLIKKIAMREIRMLKQLKHPNLVRLIEVFRRKKRLHLVFDYVDHTLLNELDRY--PRGL 354
Query: 363 SLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYM----E 418
+ I+Y Q A+ + +HRD+ N+L++ VKL DFG +R + +
Sbjct: 355 PEPMVKRIIY--QTLLAVNFCHQYNTIHRDVKPENILITRQGQVKLCDFGFARILTGPGD 528
Query: 419 DSTYYKASKGKLPIKWMAPE-SINFRRFTSASDVWMFGVCMWEIL 462
+ T Y A++ + APE + ++ DVW G E+L
Sbjct: 529 EYTDYVATRW-----YRAPELLVGDTQYGPPVDVWAIGCVFAELL 648
>32264
Length = 287
Score = 46.2 bits (108), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 20/43 (46%), Positives = 25/43 (58%)
Frame = +1
Query: 481 IENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLS 523
IE+G RL P P ++Y LM +CW Y P +RP F EL L
Sbjct: 1 IEDGYRLQQNPQTPDSVYKLMLRCWEYVPEKRPHFKELYTSLK 129
>26560
Length = 398
Score = 44.7 bits (104), Expect = 1e-04, Method: Composition-based stats.
Identities = 34/113 (30%), Positives = 59/113 (52%), Gaps = 1/113 (0%)
Frame = -1
Query: 371 LYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKL 430
YA ++ L ++ S+ V+RD+ N+L+ N V++ D GL+ + AS G
Sbjct: 344 FYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGLACDFSKKRPH-ASVGTH 168
Query: 431 PIKWMAPESI-NFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIE 482
+MAPE + + + S++D + FG CM L+ G PF+ ++N RI+
Sbjct: 167 --GYMAPEVLMKGQSYDSSADWFSFG-CMLYKLLKGHSPFR--QHNQGQARID 24
>04138
Length = 800
Score = 43.5 bits (101), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 24/85 (28%), Positives = 42/85 (49%), Gaps = 3/85 (3%)
Frame = +1
Query: 380 LAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSR-YMEDSTYYKASKGKLPIKWMAPE 438
L Y+ + +HRD+ A N+L++ +KL DFGL+R + + ++ W P
Sbjct: 52 LYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRPP 231
Query: 439 SINF--RRFTSASDVWMFGVCMWEI 461
+ R +++A D W G M E+
Sbjct: 232 ELLLGDRNYSTAIDQWGAGCIMAEM 306
>01392
Length = 1806
Score = 42.4 bits (98), Expect = 5e-04, Method: Compositional matrix adjust.
Identities = 37/122 (30%), Positives = 59/122 (48%), Gaps = 12/122 (9%)
Frame = -1
Query: 367 ASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDC---VKLGDFGLSRYME-DSTY 422
ASL++ ++ AL +L SK HRD+ N+L D VK+ DF L+ + D
Sbjct: 1785 ASLVVR--HIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGISCDGDG 1612
Query: 423 YKASKGKLPI---KWMAPESINFRRFTSAS-----DVWMFGVCMWEILMHGVKPFQGVKN 474
K + P+ ++MAPE ++ S S D+W G+ ++ I++ G PF G
Sbjct: 1611 TKTPELLTPVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILY-IMLCGYPPFYGQCG 1435
Query: 475 ND 476
D
Sbjct: 1434 ED 1429
>12786
Length = 460
Score = 41.2 bits (95), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 39/143 (27%), Positives = 69/143 (48%), Gaps = 23/143 (16%)
Frame = -3
Query: 363 SLDLASLILYAYQLSTALAYLESKRFVHRDIAARN-VLVSSNDCVKLGDFGLSRYMED-- 419
LD + Y ++ A+ L ++ +H D+ N +LV+ N +KL DFG++ ++
Sbjct: 422 GLDRMMIKFYWREMLRAVKALHNEGVIHSDLKPANFMLVAGN--LKLIDFGIANTLQQDK 249
Query: 420 STYYKASKGKLPIKWMAPESINFRRFTSA--------------------SDVWMFGVCMW 459
++ K S+ P +M+PE+I SA SDVW G C+
Sbjct: 248 TSVLKDSRVGTP-SYMSPEAIMAACDDSADDSMEEDGHRTKPKYKVGVRSDVWSLG-CIL 75
Query: 460 EILMHGVKPFQGVKNNDVIGRIE 482
+++G PFQ +KNN +G+++
Sbjct: 74 YNMVYGRTPFQHIKNN--MGKLQ 12
>03508
Length = 1463
Score = 40.0 bits (92), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 26/101 (25%), Positives = 48/101 (47%), Gaps = 2/101 (1%)
Frame = +1
Query: 371 LYAYQLSTALAYLESKRFVHRDIAARNVLVS-SNDCVKLGDFGLSRYMEDSTYYKASKGK 429
Y Y+L AL + S +HRD+ NV++ N ++L D+GL+ + Y
Sbjct: 883 FYLYELMKALDFCHSMGIMHRDVKPHNVMIDHENKKLRLIDWGLAEFYHPGMEYNVRVAS 1062
Query: 430 LPIKWMAPE-SINFRRFTSASDVWMFGVCMWEILMHGVKPF 469
K PE ++++ + + D+W G CM+ ++ +P
Sbjct: 1063RYFK--GPELLLDYQMYDYSLDMWSLG-CMFASMIFRKEPL 1176
>37602
Length = 804
Score = 38.9 bits (89), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 22/71 (30%), Positives = 32/71 (45%)
Frame = -1
Query: 341 VWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLV 400
+WI ME C G ++ V L + + L YL + +HRDI N+L+
Sbjct: 294 LWIAMEYCGGGSMQDIYHVTG-PLTEPQIAFVCRETLKGLHYLHRRGKMHRDIKGANILL 118
Query: 401 SSNDCVKLGDF 411
+ VKL DF
Sbjct: 117 TEEGDVKLADF 85
>28157
Length = 400
Score = 38.5 bits (88), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 27/98 (27%), Positives = 46/98 (46%), Gaps = 6/98 (6%)
Frame = +3
Query: 321 MRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVR--KYSLDLASLILYAYQLST 378
+ + HP+IV L G ++PV ++ME G L + L + A + + Q +
Sbjct: 72 LSRVSHPNIVCLYGACRDHPVCLVMEYAEGGSLYNVLHGSGPQPQYTAAHAMNWLLQCAL 251
Query: 379 ALAYLES---KRFVHRDIAARN-VLVSSNDCVKLGDFG 412
+ YL K +HRD+ N +L+ +K+ DFG
Sbjct: 252 GVEYLHGMKPKALIHRDLKPPNLLLIQCGTKLKICDFG 365
>38046
Length = 446
Score = 38.1 bits (87), Expect = 0.009, Method: Composition-based stats.
Identities = 14/32 (43%), Positives = 24/32 (75%)
Frame = -1
Query: 376 LSTALAYLESKRFVHRDIAARNVLVSSNDCVK 407
++ A+AY+E + F+HR++ RN+LV N+ VK
Sbjct: 98 IADAMAYMEKENFIHRNLGDRNILVGPNNRVK 3
>18481
Length = 437
Score = 38.1 bits (87), Expect = 0.010, Method: Composition-based stats.
Identities = 26/82 (31%), Positives = 44/82 (53%), Gaps = 4/82 (4%)
Frame = -1
Query: 343 IIMELCTLG-ELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVS 401
++MEL LG L + K L ++++ + QL + L ++ K F+HRD+ N L+
Sbjct: 266 LVMEL--LGPSLEELFVICKRRFTLKTILMVSDQLLSRLEFIHQKCFIHRDLKPDNFLMG 93
Query: 402 -SNDCVKLG--DFGLSRYMEDS 420
C +L DFGLS+ +D+
Sbjct: 92 LGRHCHRLYIIDFGLSKRYKDT 27
>11185
Length = 473
Score = 37.7 bits (86), Expect = 0.011, Method: Compositional matrix adjust.
Identities = 37/168 (22%), Positives = 62/168 (36%), Gaps = 21/168 (12%)
Frame = +1
Query: 372 YAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRY----MEDSTYYKASK 427
+ L T L Y+ S + D+ VL+ ++ +K DFGLS+ +E+ + A
Sbjct: 16 FGIHLVTGLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEA 195
Query: 428 G-------------KLPIK----WMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQ 470
G ++P +MAPE + SD+W G +E+
Sbjct: 196 GDQWNIQSAEEMMKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMF-------- 351
Query: 471 GVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTEL 518
+G RL P+ P +L+ D +RR + L
Sbjct: 352 ------------SGSRLSAKPS--PEFLNLLESLLQKDSTRRLSWASL 453
>07933
Length = 728
Score = 37.0 bits (84), Expect = 0.018, Method: Compositional matrix adjust.
Identities = 14/33 (42%), Positives = 22/33 (66%)
Frame = +3
Query: 490 PPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQL 522
P CP LY++M +CW+ +PS RP F +L+ +
Sbjct: 3 PNYCPNLLYNIMMQCWSAEPSARPTFHKLEQDI 101
>00486
Length = 797
Score = 36.6 bits (83), Expect = 0.029, Method: Compositional matrix adjust.
Identities = 24/81 (29%), Positives = 36/81 (44%)
Frame = -2
Query: 432 IKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPP 491
I++MAPE + A D W G M+++L G PF I +I G +L +PP
Sbjct: 766 IEYMAPEILTRTGHGKAVDWWSLGALMYDMLT-GSPPFTAENRKKTIDKILKG-KLNLPP 593
Query: 492 NCPPTLYSLMTKCWAYDPSRR 512
L+ K +P+ R
Sbjct: 592 YLTNEARGLIKKLLRKNPAER 530
>26009
Length = 886
Score = 35.0 bits (79), Expect = 0.089, Method: Compositional matrix adjust.
Identities = 15/30 (50%), Positives = 21/30 (70%)
Frame = +3
Query: 375 QLSTALAYLESKRFVHRDIAARNVLVSSND 404
QL +AL ++ SK+ VHRDI NVL+ + D
Sbjct: 735 QLVSALDFMHSKQLVHRDIKPENVLILTPD 824
>27405
Length = 532
Score = 34.3 bits (77), Expect = 0.13, Method: Compositional matrix adjust.
Identities = 20/78 (25%), Positives = 38/78 (48%)
Frame = -3
Query: 337 TENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAAR 396
T + I++L G+L L + + YA ++ L ++ S+ V+RD+
Sbjct: 341 TPEKLCFILDLMNGGDLHYHLSQHGVFTE-KEVRFYAAEVMLGLEHMHSRFVVYRDLKPA 165
Query: 397 NVLVSSNDCVKLGDFGLS 414
N+L+ N V++ D GL+
Sbjct: 164 NILLDENGHVRISDLGLA 111
>16708
Length = 1397
Score = 34.3 bits (77), Expect = 0.13, Method: Compositional matrix adjust.
Identities = 17/49 (34%), Positives = 27/49 (55%)
Frame = -1
Query: 367 ASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSR 415
A + A Q AL ++ VH D+ A NVLV ++ KL D+G+++
Sbjct: 1094 AMVCCIAGQXVCALEHIHELGVVHMDVKADNVLVDAHGNCKLTDYGIAQ 948
>02638
Length = 1490
Score = 33.9 bits (76), Expect = 0.17, Method: Compositional matrix adjust.
Identities = 30/103 (29%), Positives = 45/103 (43%), Gaps = 5/103 (4%)
Frame = +1
Query: 432 IKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKP---FQGVKNN-DVIGRIENG-ER 486
I +MAPE + + A DVW G M E M +P + N+ +I +I + +
Sbjct: 28 IAFMAPEVLRGESYGRACDVWSVGCVMIE--MCTCRPPWNSHDISNHLALIFKIASSVDP 201
Query: 487 LPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSFQNPAQ 529
P+P N P + LM +C D RP +L F +Q
Sbjct: 202 PPIPENMSPPVRDLMLRCLEQDSDFRPSAKDLLMHPLFTKYSQ 330
>15741
Length = 402
Score = 33.9 bits (76), Expect = 0.17, Method: Composition-based stats.
Identities = 15/44 (34%), Positives = 24/44 (54%)
Frame = -3
Query: 356 FLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVL 399
FL L +A ++ +A++ + + VHRD+AARNVL
Sbjct: 133 FLTSTANDLTARDFFSFALHVARGMAHVANNKIVHRDVAARNVL 2
>21210
Length = 518
Score = 32.3 bits (72), Expect = 0.57, Method: Compositional matrix adjust.
Identities = 27/95 (28%), Positives = 43/95 (45%), Gaps = 7/95 (7%)
Frame = +3
Query: 434 WMAPESINFRR----FTSASDVWMFGVCMWEILMHGVKPFQG-VKNNDVIGRIENGER-- 486
+MAPE I+ R + SDVW G+ + E L G P++ V D + ++ G
Sbjct: 18 YMAPERIDPRASSHGYDVRSDVWSLGITLME-LATGRFPYRKWVSIFDQLQQVVRGVAPC 194
Query: 487 LPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQ 521
LP + + KC D +RP++ +L A
Sbjct: 195 LPHDGAFSHDFVNFVNKCLTKDEKQRPKYNKLLAH 299
>27287
Length = 514
Score = 32.0 bits (71), Expect = 0.60, Method: Compositional matrix adjust.
Identities = 12/33 (36%), Positives = 18/33 (54%)
Frame = -2
Query: 490 PPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQL 522
PP ++ +M CW DP+ RP F+ L +L
Sbjct: 504 PPYASSEMFGIMHSCWQEDPNDRPSFSRLVQEL 406
>25019
Length = 730
Score = 31.6 bits (70), Expect = 0.79, Method: Compositional matrix adjust.
Identities = 22/62 (35%), Positives = 29/62 (46%)
Frame = +3
Query: 394 AARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWM 453
AA NVL+ + VKL DFGL + T + I++MAPE + A D W
Sbjct: 255 AAENVLLDKDGHVKLTDFGLCKEAITGTRVTHTFCG-TIEYMAPEILTRTGHGKAVDWWS 431
Query: 454 FG 455
G
Sbjct: 432 LG 437
>30593
Length = 399
Score = 28.5 bits (62), Expect = 7.2, Method: Compositional matrix adjust.
Identities = 18/72 (25%), Positives = 34/72 (47%)
Frame = +2
Query: 187 ALPSIPKLANSEKQGMRTHAVSVSETDDYAEIIDEEDTYTMPSTRDYEIQRERIELGRCI 246
++P + A S + M T +TDD+ I D+ED +PS++D + +C+
Sbjct: 221 SIPVVSSAATSVNRPMWTTI----KTDDFENITDDEDEEVIPSSQD---------IHKCL 361
Query: 247 GEGQFGDVHQGI 258
+F + Q +
Sbjct: 362 QISRFQETEQHL 397
>06601
Length = 737
Score = 28.5 bits (62), Expect = 8.1, Method: Compositional matrix adjust.
Identities = 19/51 (37%), Positives = 24/51 (47%)
Frame = +1
Query: 30 LDSVKAKTLRKLIQQTFRQFANLNREESILKFFEILSPVYRFDKECFKCAL 80
L S K KT L+ T+ LNR K F++ V+RF K C C L
Sbjct: 139 LRSAKTKTCESLVVSTY---FYLNRNA---KHFQLGKSVFRFHKMCLICVL 273
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000380634 | hsapiens_gene_ensembl | Protein
tyrosine kinase 2 beta (EC 2.7.10.2) (Focal adhesion kinase 2) (FADK
2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK
beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion
focal tyrosine kinase) (RAFTK). [Source:Uniprot/SWISSPROT;Acc:Q14289]
(596 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
06405 202 2e-52
21808 179 4e-45
09007 165 4e-41
04852 162 4e-40
11780 94 3e-36
07291 127 2e-29
17300 120 2e-29
20640 126 3e-29
07940 116 2e-26
14116 113 2e-25
18996 112 6e-25
22005 89 7e-24
08294 106 2e-23
14477 88 1e-17
13305 86 5e-17
17637 85 1e-16
17253 84 2e-16
12721 78 1e-14
01718 77 2e-14
18921 72 7e-13
19301 69 7e-12
27546 66 4e-11
14420 65 9e-11
13066 61 1e-09
00300 61 2e-09
31885 60 3e-09
07833 58 1e-08
30755 56 4e-08
21079 55 1e-07
29581 54 2e-07
19094 54 2e-07
15910 52 9e-07
19761 51 1e-06
13212 51 2e-06
01707 51 2e-06
14126 50 2e-06
25550 50 3e-06
18484 49 4e-06
00715 49 6e-06
01756 49 6e-06
12672 47 2e-05
32264 45 6e-05
26711 45 1e-04
01060 45 1e-04
04591 44 1e-04
03240 44 2e-04
01966 42 7e-04
04138 42 7e-04
35671 42 0.001
07933 39 0.004
07836 39 0.008
32359 37 0.015
28157 37 0.024
15741 35 0.079
01392 35 0.095
38046 34 0.20
27287 33 0.26
16708 32 0.76
26560 32 0.92
21433 31 1.1
37602 30 2.2
26009 30 3.2
33319 30 3.3
02638 30 3.4
00302 29 5.3
>06405
Length = 1965
Score = 202 bits (515), Expect = 2e-52, Method: Compositional matrix adjust.
Identities = 100/254 (39%), Positives = 153/254 (60%), Gaps = 5/254 (1%)
Frame = +1
Query: 200 VAVKTCKKDCTLDNKEKFMSEAVIMKNLDHPHIVKLIGI-IEEEPTWIIMELYPYGELGH 258
VAVKT K+D N F+ EA IMK + HP++V+L+G+ E P +I+ E P+G L
Sbjct: 343 VAVKTLKEDTMALND--FLEEAAIMKEMKHPNLVQLLGVCTREPPFYIVTEFMPHGNLLD 516
Query: 259 YLERNKNSLKVLTLVLY-SLQICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLS 317
YL + T ++Y + QI MAYLE+ N +HRD+A RN LVA VK+ DFGL+
Sbjct: 517 YLRSSTREENGPTALMYMATQIASGMAYLETKNFIHRDLAARNCLVADSNMVKVADFGLA 696
Query: 318 RYIEDEDYYKASVTRLPIKWMSPESINFRRFTTASDVWMFAVCMWEILSFGKQPFFWLEN 377
R ++D+ Y + PIKW +PE + F RF+T SD+W F V +WE+ ++G P+ +E
Sbjct: 697 RLMKDDTYTAHIGAKFPIKWTAPEGLAFNRFSTRSDIWAFGVLLWELATYGMSPYPGVEL 876
Query: 378 KDVIGVLEKGDRLPKPDLCPPVLYTLMTRCWDYDPSDRPRFTELVCSLSDVYQME---KD 434
+V +LE+G R+ +P P +Y LM +CW +DP DRP F E+ L ++++ ++
Sbjct: 877 TEVYHLLERGYRMERPPGTPADVYILMLKCWQWDPKDRPTFKEIHFLLENMFEKSSICEE 1056
Query: 435 IAMEQERNARYRTP 448
+ E E+N + + P
Sbjct: 1057VEKELEKNDKKQMP 1098
>21808
Length = 1011
Score = 179 bits (453), Expect = 4e-45, Method: Compositional matrix adjust.
Identities = 91/220 (41%), Positives = 135/220 (61%), Gaps = 1/220 (0%)
Frame = +1
Query: 200 VAVKTCKKDCTLDNKEKFMSEAVIMKNLDHPHIVKLIGI-IEEEPTWIIMELYPYGELGH 258
VA+KT K T+D K+ F++EA IMK L HP +++L + +++P +II EL G L
Sbjct: 28 VAIKTLKSG-TMDPKD-FLAEAQIMKKLRHPKLIQLYAVCTQDDPIFIITELMKNGSLLE 201
Query: 259 YLERNKNSLKVLTLVLYSLQICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSR 318
+L+ LK+ L+ QI MAYLES N +HRD+A RNILV+ VK+ DFGL+R
Sbjct: 202 FLQGKGRVLKLPALIDIGAQIACGMAYLESQNYIHRDLAARNILVSDNNTVKIADFGLAR 381
Query: 319 YIEDEDYYKASVTRLPIKWMSPESINFRRFTTASDVWMFAVCMWEILSFGKQPFFWLENK 378
I++++Y R PIKW +PE+ N+ RFT SDVW F + + E +++G+ P+ + N
Sbjct: 382 VIKEDEYEARVGARFPIKWTAPEAANYNRFTIKSDVWSFGILLTETVTYGRVPYPGMTNA 561
Query: 379 DVIGVLEKGDRLPKPDLCPPVLYTLMTRCWDYDPSDRPRF 418
+V+ +E G R+P P CP LY +M CW + +RP
Sbjct: 562 EVLHQVEHGYRMPCPPGCPKPLYDIMLECWRKEEMERPHL 681
>09007
Length = 1440
Score = 165 bits (418), Expect = 4e-41, Method: Compositional matrix adjust.
Identities = 99/307 (32%), Positives = 163/307 (53%), Gaps = 10/307 (3%)
Frame = -1
Query: 152 PDETLRRPGGPQYGIAREDVVLNRILXXXXXXXXXXXXXTNHKGEKINVAVKTCKKDCTL 211
P + RP + I+++ V L++ L T GEK+ VAVK KD
Sbjct: 930 PVSAVVRPARGKQLISKDCVALSKSLGQGHFGTVRQAIWTAESGEKVQVAVKCLSKDKIH 751
Query: 212 DNKEKFMSEAVIMKNLDHPHIVKLIGIIEEEPTWIIM--ELYPYGELGHYLER--NKNSL 267
+ ++F+ E IM+ LDH +IV++ G++ + I++ EL P L ++ +
Sbjct: 750 KDGQEFLKETAIMQMLDHENIVRVYGVVMDNGADIMLVTELAPMRSLLECVKEVSARVDF 571
Query: 268 KVLTLVLYSLQICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSRYI-EDEDYY 326
V L +S Q+C M+YLES VHRD+A RNIL+ S VK+ D G+S + ++YY
Sbjct: 570 SVPRLCDFSQQVCDGMSYLESKRLVHRDLAARNILLFSKSKVKISDVGVSGALGAGKEYY 391
Query: 327 KASVT---RLPIKWMSPESINFRRFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGV 383
++ T + + W +PES F++ASDVW F V +WE + G QP+ L + ++
Sbjct: 390 QSQQTIHLQNAVAWCAPESFRNLCFSSASDVWAFGVLLWEFFTHGFQPWAGLNGQQIMEA 211
Query: 384 LE--KGDRLPKPDLCPPVLYTLMTRCWDYDPSDRPRFTELVCSLSDVYQMEKDIAMEQER 441
++ + RL +PDLCP Y +M +CW+ +P RP F++L +L + + I ++ +
Sbjct: 210 VDAPQSQRLEQPDLCPKEYYAVMLKCWEQEPQRRPTFSQLFLTLPQI----RPIQVKAVK 43
Query: 442 NARYRTP 448
+A TP
Sbjct: 42 DAPSSTP 22
>04852
Length = 1462
Score = 162 bits (409), Expect = 4e-40, Method: Compositional matrix adjust.
Identities = 92/255 (36%), Positives = 135/255 (52%), Gaps = 31/255 (12%)
Frame = +1
Query: 199 NVAVKTCKKDCTLDNKEKFMSEAVIMKNL----DHPHIVKLIGI-IEEEPTWIIMELYPY 253
VAVK + T ++ F+ E +MK + H +IV +G + P W+I+E
Sbjct: 25 TVAVKMLRDIVTAVEEQDFVQELQVMKAVKKMGSHINIVNFLGCCTQGGPLWVIVEFAKN 204
Query: 254 GELGHYLERNKNSLKVL------------------------TLVLYSLQICKAMAYLESI 289
G L +LE ++ + L+ Y+ QI + M +L S
Sbjct: 205 GNLRDFLESCRDGINGYGKFVSPQDPGWYTKTPGGHVIRRKNLLSYAFQIARGMEFLASR 384
Query: 290 NCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKA-SVTRLPIKWMSPESINFRRF 348
C+HRD+A RN+LV +K+ DFGLSR DYYK S RLP+KWM+PE++ R+
Sbjct: 385 KCIHRDLAARNVLVTEEHVLKIADFGLSR---TGDYYKKRSGGRLPVKWMAPEALFDMRY 555
Query: 349 TTASDVWMFAVCMWEILSFGKQPFFWLENKDVIG-VLEKGDRLPKPDLCPPVLYTLMTRC 407
TT SDVW F V +WEI S G P+ + N+++ +L+ R+P+P+L LY +M RC
Sbjct: 556 TTKSDVWSFGVVLWEIFSLGGMPYASIPNEELYSKLLDDAYRMPRPELASGNLYAIMERC 735
Query: 408 WDYDPSDRPRFTELV 422
W PSDRP F++LV
Sbjct: 736 WLNRPSDRPEFSQLV 780
>11780
Length = 1713
Score = 94.0 bits (232), Expect(2) = 3e-36, Method: Compositional matrix adjust.
Identities = 53/146 (36%), Positives = 85/146 (58%), Gaps = 2/146 (1%)
Frame = +3
Query: 200 VAVKTCK-KDCTLDNKEKFMSEAVIMKNLDHPHIVKLIGIIEEEPTWIIMELYPYGELGH 258
VA+K K KD ++ F+ EA +M +L H ++V+LIG++ E +++ E G L
Sbjct: 675 VAIKQLKDKD---RGEQSFLQEASVMTSLRHDNLVRLIGVVLGETIFLVTEFMGKGNLVE 845
Query: 259 YLE-RNKNSLKVLTLVLYSLQICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLS 317
YL R ++ + + ++ C AM YLES VHRD+A RN+LV K+ DFGL+
Sbjct: 846 YLRSRGRSVITKKDQINFATDTCAAMEYLESKRLVHRDLAARNVLVHDDGKAKVSDFGLA 1025
Query: 318 RYIEDEDYYKASVTRLPIKWMSPESI 343
++ D+ + SV + PIKW +PE++
Sbjct: 1026KF---GDFSQTSV-KFPIKWTAPEAL 1091
Score = 76.6 bits (187), Expect(2) = 3e-36, Method: Compositional matrix adjust.
Identities = 31/81 (38%), Positives = 55/81 (67%)
Frame = +1
Query: 347 RFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTR 406
+FT+ SD+W F + +WEI SFG+ P+ + DV+ +E+G R+ P+ CPP +Y++M +
Sbjct: 1102 KFTSKSDMWSFGILLWEIYSFGRVPYPRIPLTDVVMHVERGYRMEAPEGCPPEIYSIMKQ 1281
Query: 407 CWDYDPSDRPRFTELVCSLSD 427
W+ DP++RP F ++ L++
Sbjct: 1282 AWELDPNERPTFKSVLARLNN 1344
>07291
Length = 833
Score = 127 bits (318), Expect = 2e-29, Method: Compositional matrix adjust.
Identities = 61/157 (38%), Positives = 95/157 (60%), Gaps = 2/157 (1%)
Frame = +1
Query: 267 LKVLTLVLYSLQICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYY 326
L V+ L+ + QI MAYL+ + VHR++A RN +V ++L D+G++ + + YY
Sbjct: 40 LTVVQLLDFGRQIADGMAYLQEVKVVHRNLAARNCIVTEDGRLQLSDYGVTGSLFPQSYY 219
Query: 327 KA--SVTRLPIKWMSPESINFRRFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVL 384
A S R +KWM+PE+I+ F++ SDVW F V +WE+L+ G P+ +EN ++ L
Sbjct: 220 TADDSPARDLVKWMAPETIDNFHFSSKSDVWAFGVVLWELLTRGITPYPDVENSSLLPYL 399
Query: 385 EKGDRLPKPDLCPPVLYTLMTRCWDYDPSDRPRFTEL 421
++G R+ KP P +Y +MT CW+ P RP F EL
Sbjct: 400 KEGHRMKKPKQSPEPVYEMMTACWNESPEQRPDFAEL 510
>17300
Length = 480
Score = 120 bits (301), Expect(2) = 2e-29, Method: Composition-based stats.
Identities = 55/116 (47%), Positives = 76/116 (65%), Gaps = 3/116 (2%)
Frame = +1
Query: 279 ICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSRYIED---EDYYKASVTRLPI 335
I M L + VHRD+A RNILV K+ DFGLSR IE E Y ++P+
Sbjct: 1 ISSGMGXLADMGYVHRDLAARNILVNEILVCKVADFGLSREIESDTTEGAYTTKGGKIPV 180
Query: 336 KWMSPESINFRRFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLP 391
+W +PE+I +R+FT+ASDVW F V MWE++S+G++P++ N+DVI +EKG RLP
Sbjct: 181 RWTAPEAIAYRKFTSASDVWSFGVVMWEVMSYGERPYWNWSNQDVIKAVEKGYRLP 348
Score = 27.3 bits (59), Expect(2) = 2e-29, Method: Compositional matrix adjust.
Identities = 11/35 (31%), Positives = 19/35 (54%)
Frame = +2
Query: 396 CPPVLYTLMTRCWDYDPSDRPRFTELVCSLSDVYQ 430
CP L+ LM W + S RP+ + +V +L + +
Sbjct: 359 CPEALHQLMLDAWQKERSHRPKMSMVVKTLDKLIR 463
>20640
Length = 1492
Score = 126 bits (316), Expect = 3e-29, Method: Compositional matrix adjust.
Identities = 58/139 (41%), Positives = 88/139 (63%), Gaps = 1/139 (0%)
Frame = +1
Query: 292 VHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKAS-VTRLPIKWMSPESINFRRFTT 350
VHRD+A RN LV VK+ DFGL+R + DYY+ S +PI+WM E+I + +F+T
Sbjct: 10 VHRDLATRNCLVGHDLVVKISDFGLARSVHSVDYYRGSEHDAIPIRWMPLEAILYNKFST 189
Query: 351 ASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTRCWDY 410
SDVW F V +WEI +F QP++ L +++V+ +++G L P+ PP +Y LM +CW
Sbjct: 190 QSDVWSFGVVLWEIFAFALQPYYGLTHEEVVRFVKEGKVLACPERTPPPMYELMKQCWHR 369
Query: 411 DPSDRPRFTELVCSLSDVY 429
P+ RP F L +L +++
Sbjct: 370 RPATRPSFHTLHKTLENMH 426
>07940
Length = 1336
Score = 116 bits (291), Expect = 2e-26, Method: Compositional matrix adjust.
Identities = 51/113 (45%), Positives = 78/113 (69%), Gaps = 4/113 (3%)
Frame = -3
Query: 264 KNSLKVLT---LVLYSLQICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSRYI 320
++ LK+LT L+ Y+ Q+ + M YL S C+HRD+A RN+LVA +K+ DFGL+R +
Sbjct: 374 QDMLKMLTPKDLISYAYQVARGMEYLASKQCIHRDLAARNVLVAEEYVLKIADFGLTRNL 195
Query: 321 EDEDYY-KASVTRLPIKWMSPESINFRRFTTASDVWMFAVCMWEILSFGKQPF 372
+ DYY K + RLP+KWM+PE++ R++T+ SDVW + V +WEI + G P+
Sbjct: 194 QQFDYYRKTTDGRLPVKWMAPEALFDRKYTSKSDVWSYGVLLWEIFTLGGNPY 36
>14116
Length = 1017
Score = 113 bits (283), Expect = 2e-25, Method: Compositional matrix adjust.
Identities = 61/185 (32%), Positives = 110/185 (59%), Gaps = 6/185 (3%)
Frame = -1
Query: 194 KGEKINVAVKTCKKDCTLDNK-EKFMSEAVIMKNLDHPHIVKLIGI---IEEEPTWIIME 249
KG+ I VAVKT + + + + F+ EA+IMK+ H +++ LIGI +++ P +++
Sbjct: 555 KGD-ILVAVKTLHNNNPREIELQSFLQEALIMKDFHHSNVLTLIGICLNLDDMPL-VVLP 382
Query: 250 LYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYLESINCVHRDIAVRNILVASPECV 309
+G+L Y+ +++ + L++Y + I + M YL + VHRD+A RN ++ V
Sbjct: 381 FMKHGDLLTYIRDDQHQPTIKDLIMYGVDIARGMDYLAGLKFVHRDLAARNCMLDEDFHV 202
Query: 310 KLGDFGLSRYIEDEDYYKA--SVTRLPIKWMSPESINFRRFTTASDVWMFAVCMWEILSF 367
K+ DFGL+R I +++YY + +LP+KWM+ ES+ + + +DVW + V +WE+L+
Sbjct: 201 KVADFGLARDIYEKEYYSSENKKAKLPVKWMALESLEKGNYDSKTDVWSYGVVLWELLTR 22
Query: 368 GKQPF 372
G
Sbjct: 21 GSDAL 7
>18996
Length = 491
Score = 112 bits (279), Expect = 6e-25, Method: Compositional matrix adjust.
Identities = 57/137 (41%), Positives = 84/137 (61%), Gaps = 6/137 (4%)
Frame = +2
Query: 292 VHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVTR-LPIKWMSPESINFRRFTT 350
+HRD+A RNILV CVK+ DFGL+++ + YY R +PIKW SPE+I +F++
Sbjct: 2 IHRDLAARNILVDR-SCVKISDFGLAQFANADGYYYGISQRDIPIKWYSPEAIETCKFSS 178
Query: 351 ASDVWMFAVCMWEILSFGKQPFFW----LENKDVIGVLEKGDRLPKPDLCPPVLYT-LMT 405
SDVW + V ++E+ S G+ P L ++ + L KG+RLPKP+LC +Y+ LM
Sbjct: 179 YSDVWSYGVTLFEMFSRGEIPNLLPGHDLTQEEFLNRLRKGERLPKPELCSDFVYSELMR 358
Query: 406 RCWDYDPSDRPRFTELV 422
CW P RP F +++
Sbjct: 359 PCWHEMPKSRPTFHQII 409
>22005
Length = 873
Score = 89.4 bits (220), Expect(2) = 7e-24, Method: Compositional matrix adjust.
Identities = 64/208 (30%), Positives = 96/208 (46%), Gaps = 45/208 (21%)
Frame = +1
Query: 203 KTCKKDCTLDNKEKFMSEAVIMKNLDHPHIVKLIGIIE-EEPTWIIMELYPYGELGHYL- 260
K K+D + D + F EA +M + DHP+IVKL+G+ +P ++ E G+L +L
Sbjct: 109 KMLKEDASEDLQSDFEREASLMADFDHPNIVKLLGVCAIGKPMCLLFEFMSKGDLNDFLR 288
Query: 261 -----------------------------------------ERNKNSLKVLTLVLY-SLQ 278
+R+ + + LY S Q
Sbjct: 289 LCSPENYNLPVSRSQNLVVDLEDGLRVEVEAEECEKDTQSEDRDCSGMLXTKDQLYISQQ 468
Query: 279 ICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKAS-VTRLPIKW 337
I MAYL + VHRD+A R + + + DFGL+R + DYY+ S +PI+W
Sbjct: 469 ISAGMAYLAQKDYVHRDLATRTVXSRTT*-S*ISDFGLARSVHSVDYYRGSEQDAIPIRW 645
Query: 338 MSPESINFRRFTTASDVWMFAVCMWEIL 365
M E+I + +F+T SDVW F V +WEIL
Sbjct: 646 MPLEAILYSKFSTQSDVWSFGVVLWEIL 729
Score = 39.7 bits (91), Expect(2) = 7e-24, Method: Compositional matrix adjust.
Identities = 15/49 (30%), Positives = 28/49 (57%)
Frame = +3
Query: 365 LSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTRCWDYDPS 413
+F QP++ L +++V+ ++ G L +P P +Y LM +CW P+
Sbjct: 726 FAFALQPYYGLTHEEVVNYVKAGKILEQPTKTPHQVYELMKQCWQRRPA 872
>08294
Length = 1849
Score = 106 bits (265), Expect = 2e-23, Method: Compositional matrix adjust.
Identities = 68/210 (32%), Positives = 104/210 (49%), Gaps = 13/210 (6%)
Frame = +2
Query: 230 PHIVKLIGIIEE-EPTWIIMELYPYGELGHYL--ERNKNS----LKVLTLVL-----YSL 277
P+IV +G+ E EP ++I E +G+L +L RN N +V L L
Sbjct: 887 PNIVHFMGVCREAEPHFLITEYCDWGDLKQFLLATRNDNGRGRGTRVPALALSQKLGMGQ 1066
Query: 278 QICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVTRLPIKW 337
Q+ M L + VH D+A RN+L+ S +K+ LS + +YY +P++W
Sbjct: 1067 QVAAGMEALSNQGLVHGDLAARNVLLTSRMQLKVARPALSGDVYASEYYPLHQRLVPLRW 1246
Query: 338 MSPESINFRRFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGD-RLPKPDLC 396
+ PE + TT DVW F V +WE+L P+ + +++V+ L+ L PD
Sbjct: 1247 LPPEGVLEDSATTCGDVWAFGVFLWEVLQLADLPYRLMSDEEVLRSLQHSQAALDSPD-A 1423
Query: 397 PPVLYTLMTRCWDYDPSDRPRFTELVCSLS 426
PP L +L+ RC PS RP F+E+ LS
Sbjct: 1424 PPALLSLLQRCTAQQPSQRPPFSEICSVLS 1513
>14477
Length = 493
Score = 87.8 bits (216), Expect = 1e-17, Method: Compositional matrix adjust.
Identities = 51/134 (38%), Positives = 79/134 (58%), Gaps = 2/134 (1%)
Frame = -1
Query: 197 KINVAVKTCKK-DCTLDNKEKFMSEAVIMKNLDHPHIVKLIGIIEEEPTWIIMELYPYGE 255
+I VA+K K D + + + EA +MK +DH HIV+LIG+ E E +++EL G
Sbjct: 409 EIPVAIKVLKNADLDPSVQSELIKEAEVMKKMDHMHIVRLIGLCEGETMMLVLELAKLGP 230
Query: 256 LGHYLERNKNSLKVLTLVLYSLQICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFG 315
L +L +NK+ L + ++ Q+ + M YLE+ VHRD+A RNIL+ K+ DFG
Sbjct: 229 LNKFLPKNKH-LPLWNILELMWQVSQGMEYLEANKFVHRDLAARNILLCDEHFAKISDFG 53
Query: 316 LSRYIEDE-DYYKA 328
+S+ + E +YY A
Sbjct: 52 MSKTLSRENNYYMA 11
>13305
Length = 549
Score = 85.9 bits (211), Expect = 5e-17, Method: Compositional matrix adjust.
Identities = 42/113 (37%), Positives = 64/113 (56%), Gaps = 3/113 (2%)
Frame = +2
Query: 331 TRLPIKWMSPESINFRRFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRL 390
TR+PI+WM+ ES+ +TT SDVW F V +WEI + G P+ + + + L+ G RL
Sbjct: 5 TRVPIRWMAVESLFNNTYTTQSDVWSFGVVLWEIFTLGGTPYSSTDTQQLFAFLKDGYRL 184
Query: 391 PKPDLCPPVLYTLMTRCWDYDPSDRPRFTELVCSLS---DVYQMEKDIAMEQE 440
+P LC Y +M +CW+ + RP F EL L D Q+ +++ E+E
Sbjct: 185 KRPKLCDQNTYAMMLQCWNENAQRRPTFPELCGRLQRMLDDCQVYMNLSTEEE 343
>17637
Length = 447
Score = 84.7 bits (208), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 46/122 (37%), Positives = 68/122 (55%), Gaps = 1/122 (0%)
Frame = +1
Query: 309 VKLGDFGLSRYIEDEDYYKASVTRL-PIKWMSPESINFRRFTTASDVWMFAVCMWEILSF 367
VKL D LSR + DY PIKW+S E++ + SDVW F V MWE+ +
Sbjct: 28 VKLTDSALSRDLFSGDYNCLGDGEYRPIKWLSLEALQKSHYNEGSDVWSFGVLMWEMCTL 207
Query: 368 GKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTRCWDYDPSDRPRFTELVCSLSD 427
GK P+ ++ ++ L+ G RL +P CP L+T+M CW P++RP F++L LS+
Sbjct: 208 GKLPYAEIDPYEMEHYLKDGYRLAQPFNCPDELFTIMAYCWASMPAERPSFSQLQICLSE 387
Query: 428 VY 429
+
Sbjct: 388 FH 393
>17253
Length = 483
Score = 83.6 bits (205), Expect = 2e-16, Method: Composition-based stats.
Identities = 50/160 (31%), Positives = 83/160 (51%), Gaps = 15/160 (9%)
Frame = -1
Query: 193 HKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKNLD-HPHIVKLIGIIE-EEPTWIIMEL 250
H + VAVKT + T K +F+ E IM+ L HP++V +G +P I+ME
Sbjct: 480 HARQWDTVAVKTHNEAATDAEKSEFLRELSIMRKLPRHPNVVSFMGCCTMSDPALILMEF 301
Query: 251 YPYGELGHYLERNK-----------NSLKVLTLVLYSLQICKAMAYLESINCVHRDIAVR 299
+G+L +L + + N L ++L + + MA++ + VHRD+A R
Sbjct: 300 CCHGDLLSFLRKRRPDRTVFLTSTANDLTARDFFSFALHVARGMAHVANNKIVHRDVAAR 121
Query: 300 NILVASPECVKLGDFGLSRYIEDEDYYKASVTR--LPIKW 337
N+L++ K+ DFGLSR + D++ V+R LP++W
Sbjct: 120 NVLISERNVCKVSDFGLSRRVGDQNDVYEIVSRRPLPLRW 1
>12721
Length = 821
Score = 77.8 bits (190), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 60/233 (25%), Positives = 110/233 (47%), Gaps = 8/233 (3%)
Frame = +1
Query: 191 TNHKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKNLDHPHIVKLIG--IIEEEPTWIIM 248
T+ G ++ V +K +E +E V+M++ HP+IV++ ++ +E W++M
Sbjct: 148 TSRDGRQMAVKKMDLRKQ---QRRELLFNEVVVMRDYHHPNIVEMYNSYLVNDE-LWVVM 315
Query: 249 ELYPYGELGHYLERNK-NSLKVLTLVLYSLQICKAMAYLESINCVHRDIAVRNILVASPE 307
E G L + N+ + +++ T+ L KA+A+L + +HRDI +IL++
Sbjct: 316 EFMEGGALTDIVTNNRMDEVQIATVCRACL---KALAFLHANGVIHRDIKSDSILLSHDG 486
Query: 308 CVKLGDFGLSRYIEDEDYYKASVTRLPIKWMSPESINFRRFTTASDVWMFAVCMWEILSF 367
VKL DFG + + + S+ P WM+PE I+ + D+W + + E++
Sbjct: 487 KVKLXDFGFCAQVTQDLQKRKSLVGTPY-WMAPEVISRLPYGPEVDIWSLGIMVMEMID- 660
Query: 368 GKQPFFWLENKDVIGVLEKGDRLPKPDL-----CPPVLYTLMTRCWDYDPSDR 415
+ PFF N+ + + + +P P L P L + R DP R
Sbjct: 661 AEPPFF---NEPPLQAMRRIRDMPPPKLRNTHKISPRLQGFIDRMLVRDPHQR 810
>01718
Length = 959
Score = 76.6 bits (187), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 62/255 (24%), Positives = 110/255 (43%), Gaps = 10/255 (3%)
Frame = +3
Query: 196 EKINVAVKTCKKDCTLDNKEKFMSEAVIMKNLDHPHIVKLIGI-IEEEPTWIIMELYPYG 254
+I V K + N+ + E ++ L H +I++ +G+ + E + E P G
Sbjct: 210 HRITGQVMALKMNTMTSNRHNMLREVQLLNRLQHANILRFMGVCVHEGQLHALTEYIPSG 389
Query: 255 ELGHYLERNKNSLKVLTLVLYSLQICKAMAYLESINCVHRDIAVRNILVASPEC----VK 310
L LE+ L + +L + + + YL S +HRD+ +NIL+ +
Sbjct: 390 NLEQLLEKKDEELPWTQRIQLTLGLARGLDYLHSTRFIHRDLTSKNILIRREDNHGYHAV 569
Query: 311 LGDFGLSRYIEDE-DYYKASVTRLPIKWMSPESINFRRFTTASDVWMFAVCMWEILSFGK 369
+ DFGL+ I D D K P WM+PE +N + +D++ + M EI +
Sbjct: 570 IADFGLATKIPDPLDKEKLPTVGSPY-WMAPEVLNGHFYNERADLFSVGIIMCEITARIP 746
Query: 370 QPFFWLENKDVIGVLEKGDRLPKPDL---CPPVLYTLMTRCWDYDPSDRPRFTELVCSLS 426
+ + GV D + ++ CP L +C DP RPR E++ L
Sbjct: 747 ADPDIMPRMNNFGV----DYVALSEMISYCPLDYLQLAFKCCQVDPQKRPRGVEIIEWLE 914
Query: 427 DVYQ-MEKDIAMEQE 440
+++ ++ DI Q+
Sbjct: 915 KIFKNLKNDIFTRQQ 959
>18921
Length = 697
Score = 71.6 bits (174), Expect = 7e-13, Method: Compositional matrix adjust.
Identities = 55/183 (30%), Positives = 88/183 (48%), Gaps = 4/183 (2%)
Frame = +2
Query: 193 HKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKNLDHPHIVKLIG-IIEEEPTWIIMELY 251
HK +A+K D L ++ + E IM+ D +IVK G + WI+ME
Sbjct: 92 HKETGQVLAIKQVPVDTDL---QEIIKEISIMQQCDSKYIVKYYGSYFKNTDLWIVMEYC 262
Query: 252 PYGELGHYLE-RNKNSLK--VLTLVLYSLQICKAMAYLESINCVHRDIAVRNILVASPEC 308
G + + RNK ++ + T++ Y+L K + YL S +HRDI NIL+ +
Sbjct: 263 GAGSVSDIMRLRNKTLVEREIATILYYTL---KGLXYLHSRRKIHRDIKAGNILLNNEGH 433
Query: 309 VKLGDFGLSRYIEDEDYYKASVTRLPIKWMSPESINFRRFTTASDVWMFAVCMWEILSFG 368
KL DFG++ + D + +V P WM+PE I + +D+W + E ++ G
Sbjct: 434 AKLADFGVAGQLTDTMAKRNTVIGTPY-WMAPEVIQEIGYDCVADIWSLGITALE-MAEG 607
Query: 369 KQP 371
K P
Sbjct: 608 KPP 616
>19301
Length = 712
Score = 68.6 bits (166), Expect = 7e-12, Method: Compositional matrix adjust.
Identities = 38/95 (40%), Positives = 53/95 (55%), Gaps = 1/95 (1%)
Frame = +2
Query: 224 MKNLDHPHIVKLIGIIEEEPTW-IIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKA 282
++ L+HP+I+ G+ + P + IIME PYG+L L K L L +S QI
Sbjct: 431 LRKLNHPNIISFKGVCTQAPCYCIIMEYCPYGQLYEVLRDGKEIPPALVLD-WSKQIASG 607
Query: 283 MAYLESINCVHRDIAVRNILVASPECVKLGDFGLS 317
M YL S +HRD+ N+LVA + VK+ DFG S
Sbjct: 608 MNYLHSHKIIHRDLKSPNVLVAKNDVVKISDFGTS 712
>27546
Length = 426
Score = 66.2 bits (160), Expect = 4e-11, Method: Composition-based stats.
Identities = 42/134 (31%), Positives = 71/134 (52%), Gaps = 3/134 (2%)
Frame = -1
Query: 192 NHKGEKINVAVKTCKK-DCTLDNKEKFM-SEAVIMKNLDHPHIVKLIGIIEEEPT-WIIM 248
+ G +N+A K K +D +KF E I+ LDHP+I+++ I++ P +I M
Sbjct: 420 DESGHGVNLACKIIDKAKAPIDFVKKFFPRELEILTRLDHPNIIQIHSILQRGPKIFIFM 241
Query: 249 ELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYLESINCVHRDIAVRNILVASPEC 308
G++ ++++ + T V + Q+ KA+ YL S + HRD+ NIL++
Sbjct: 240 RYAEKGDMLSHIKKTGPIDEAQTKVWF-FQMAKALQYLHSHDIAHRDLKCENILLSKRLN 64
Query: 309 VKLGDFGLSRYIED 322
VK+ DFG +RY D
Sbjct: 63 VKIADFGFARYCRD 22
>14420
Length = 528
Score = 64.7 bits (156), Expect = 9e-11, Method: Compositional matrix adjust.
Identities = 44/162 (27%), Positives = 78/162 (48%), Gaps = 2/162 (1%)
Frame = +2
Query: 214 KEKFMSEAVIMKNLDHPHIVK-LIGIIEEEPTWIIMELYPYGELGHYL-ERNKNSLKVLT 271
KE ++E ++M+ +P+IV L + E W++ME G L + E + ++
Sbjct: 32 KELIINEILVMRENQNPNIVNYLDSYLVGEELWVVMEFLAGGSLTDVVTETCMDEGQIAA 211
Query: 272 LVLYSLQICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVT 331
+ LQ A+ +L +HRDI NIL+ VKL DFG + E ++++
Sbjct: 212 VCRECLQ---ALEFLHENQVIHRDIKSDNILLGMDGSVKLTDFGFCAQLSPEQSKRSTMV 382
Query: 332 RLPIKWMSPESINFRRFTTASDVWMFAVCMWEILSFGKQPFF 373
P WM+PE + +++ D+W V E++ G+ P+
Sbjct: 383 GTP-YWMAPEVVTRKQYGPTVDIWSLGVMCIEMIE-GEPPYL 502
>13066
Length = 551
Score = 61.2 bits (147), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 41/126 (32%), Positives = 66/126 (52%), Gaps = 3/126 (2%)
Frame = +3
Query: 195 GEKINVAVKTCKKD-CTLDNKEKFM-SEAVIMKNLDHPHIVKLIGIIEEEP-TWIIMELY 251
G I +A K K+ +D EKF E ++ LDHP+I+++ I++ P +I M
Sbjct: 45 GRNIKLACKIIDKEKAPVDFVEKFFPRELDLLTKLDHPYIIQIHSILQRXPKNFIFMRFA 224
Query: 252 PYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYLESINCVHRDIAVRNILVASPECVKL 311
G+L Y++ +K ++ Q+ A+ YL S + HRD+ NIL++S VKL
Sbjct: 225 ERGDLLTYIQE-VGFVKEKQAKIWFYQMTTALNYLHSYDVAHRDLKCENILLSSHFNVKL 401
Query: 312 GDFGLS 317
DFG +
Sbjct: 402 ADFGFA 419
>00300
Length = 2318
Score = 60.8 bits (146), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 55/218 (25%), Positives = 97/218 (44%), Gaps = 8/218 (3%)
Frame = -1
Query: 220 EAVIMKNLDHPHIVKLIGI-IEEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQ 278
E I + + H ++VK G+ + ++ + ME Y + G E K L + Y+ +
Sbjct: 1511 EIKIFEGIQHENLVKYYGVEVHKDEMLMFME---YCDTGTIEEAAKMGLPEYLIRRYTRE 1341
Query: 279 ICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVTRL--PIK 336
I A+ +L + VHRDI NI + S VKLGDFG S ++ L
Sbjct: 1340 IVLAVNHLHENSIVHRDIKGANIFLTSNGHVKLGDFGCSVKLKSHTTMPGEFHNLVGTTA 1161
Query: 337 WMSPESINFRR---FTTASDVWMFAVCMWEILSFGKQPFFWLENK-DVIGVLEKGDRLPK 392
+M+PE + A+D+W + E ++ GK+P+ L+N ++ + G +
Sbjct: 1160 YMAPEVFTQNDQGGYGRAADIWSLGCVVIE-MATGKRPWHDLDNNYQIMYKVGIGHKPAV 984
Query: 393 PDLCPPVLYTLMTRCWDYDPSDRPRFTELV-CSLSDVY 429
PD + +DP+ R ++L+ + + VY
Sbjct: 983 PDSLSVEGKHFLDLIMCHDPAQRALASQLLDHTFTKVY 870
>31885
Length = 529
Score = 59.7 bits (143), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 44/156 (28%), Positives = 83/156 (53%), Gaps = 6/156 (3%)
Frame = -2
Query: 223 IMKNLDHPHIVKL-IGIIEEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICK 281
++ LDHP +V L +EE +++++L+ G+L +++++ + S + + Y Q+
Sbjct: 513 MLTRLDHPFLVNLWYAFQDEEDLFMVVDLFLGGDLRYHMQQ-EVSFREDCVKFYLCQLAL 337
Query: 282 AMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVTRLPIKWMSPE 341
+ YL S VHRDI NIL+ + DF ++ +ED++ ++ P +M+PE
Sbjct: 336 VLDYLRSQKIVHRDIKPDNILLDEQGHCHVTDFNIATQLEDDELATSTSGTRP--YMAPE 163
Query: 342 ----SINFRR-FTTASDVWMFAVCMWEILSFGKQPF 372
+IN RR + D W V ++E+L ++PF
Sbjct: 162 VYGVAINERRGYGFPVDWWSLGVSLFELLK-KRRPF 58
>07833
Length = 1504
Score = 58.2 bits (139), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 52/221 (23%), Positives = 101/221 (45%), Gaps = 15/221 (6%)
Frame = -3
Query: 217 FMSEAVIMKNLDHPHIVKLIGIIEEEPTWIIM-ELYPYGELGHYLERNKNSLKVLTLVL- 274
FM E ++ +HP+++ ++ + P +++ + P+G L + L + L
Sbjct: 1478 FMEEFPRLRIFNHPNVLPVLACCNQPPNLVLISQFMPFGSLYNTLHGESGIVVDQNQSLR 1299
Query: 275 YSLQICKAMAYLESINCVHRDIAVRNILVASPEC---------VKLGDFGLSRYIEDEDY 325
+++ I + M +L S+ + + N L+ S + + D+ S + + + Y
Sbjct: 1298 FAMDIARGMEFLHSM-----EPTIPNFLLTSKHVMIDEDLTARINMADYCFSFHEKGKVY 1134
Query: 326 YKASVTRLPIKWMSPESINFRR---FTTASDVWMFAVCMWEILSFGKQPFFWLENKDV-I 381
A WM+PE++ R T A+D+W FA+ MWE L + PF L + +V +
Sbjct: 1133 SPA--------WMAPEALQRRPDDINTRAADMWSFAILMWE-LETREVPFAELSSMEVGM 981
Query: 382 GVLEKGDRLPKPDLCPPVLYTLMTRCWDYDPSDRPRFTELV 422
V +G R+ P + L+ C + +P RPRF ++
Sbjct: 980 KVALEGLRISIPPGISLHMSRLIKICMNEEPGKRPRFDMII 858
>30755
Length = 1137
Score = 55.8 bits (133), Expect = 4e-08, Method: Compositional matrix adjust.
Identities = 32/107 (29%), Positives = 58/107 (54%), Gaps = 1/107 (0%)
Frame = +2
Query: 274 LYSLQICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVTRL 333
Y +I A+ YL S ++RD+ + N+L+ +K+ DFGL + ED Y + + T
Sbjct: 44 FYGAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCK--EDITYGRTTKTFC 217
Query: 334 PI-KWMSPESINFRRFTTASDVWMFAVCMWEILSFGKQPFFWLENKD 379
++++PE ++ + A D W V M+E++ G+ PF+ N+D
Sbjct: 218 GTPEYLAPEVLDDNDYGRAVDWWGTGVVMYEMIC-GRLPFY---NRD 346
>21079
Length = 878
Score = 54.7 bits (130), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 40/146 (27%), Positives = 69/146 (47%), Gaps = 3/146 (2%)
Frame = +1
Query: 229 HPHIVKLIGIIEEEPTWI-IMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYLE 287
HP ++ L E T + +ME GEL + R+ L V + QIC + Y+
Sbjct: 1 HPKLLMLWDAFEAPRTMVLVMEFVGAGELFERVIRDDFVLTERDCVHFVRQICSGVGYMH 180
Query: 288 SINCVHRDIAVRNILVASPEC--VKLGDFGLSRYIEDEDYYKASVTRLPIKWMSPESINF 345
+ + +H D+ N+L S +K+ DFGL+R+ + D V ++++PE +N+
Sbjct: 181 TQSILHLDLKPENVLCVSDNSNQIKIIDFGLARFYKPGD--SLQVLFGTPEFIAPEVVNY 354
Query: 346 RRFTTASDVWMFAVCMWEILSFGKQP 371
+D+W V + +LS G P
Sbjct: 355 DEINFTTDMWSIGVICYILLS-GLSP 429
>29581
Length = 1278
Score = 54.3 bits (129), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 43/158 (27%), Positives = 73/158 (46%), Gaps = 6/158 (3%)
Frame = -2
Query: 221 AVIMKNLDHPHIVKLIGII---EEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSL 277
+ + NL H +IV+L ++ + +++ME Y +L L+ + L
Sbjct: 1202 STFLLNLRHQNIVQLQEVVVGKSLDSLFLVME-YCEQDLASLLDNMPAPFSESQVKCIVL 1026
Query: 278 QICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSR-YIEDEDYYKASVTRLPIK 336
Q+ K + YL +HRD+ V N+L+ CVK+ DFGL+R Y + + V L
Sbjct: 1025 QLLKGLRYLHEAFIIHRDLKVSNLLMTDKGCVKIADFGLARNYGKPQKPMTPKVVTL--- 855
Query: 337 WMSPESINF--RRFTTASDVWMFAVCMWEILSFGKQPF 372
W + F + +TA D+W + E+L G +P
Sbjct: 854 WYRAPELLFGSKTHSTAIDMWSAGCILGELL--GHKPL 747
>19094
Length = 898
Score = 53.9 bits (128), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 33/105 (31%), Positives = 54/105 (51%), Gaps = 2/105 (1%)
Frame = +1
Query: 262 RNKNSLK--VLTLVLYSLQICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSRY 319
RNK ++ + T++ Y+L K + YL S +HRDI NIL+ + KL DFG++
Sbjct: 37 RNKTLVEREIATILYYTL---KGL*YLHSRRKIHRDIKAGNILLNNEGHAKLADFGVAGQ 207
Query: 320 IEDEDYYKASVTRLPIKWMSPESINFRRFTTASDVWMFAVCMWEI 364
+ D + +V P WM+PE I + +D+W + E+
Sbjct: 208 LTDTMAKRNTVIGTP-YWMAPEVIQEIGYDCVADIWSLGITALEM 339
>15910
Length = 1361
Score = 51.6 bits (122), Expect = 9e-07, Method: Compositional matrix adjust.
Identities = 40/123 (32%), Positives = 64/123 (52%), Gaps = 6/123 (4%)
Frame = +2
Query: 257 GHYLERNKNSLKVLTLVLYSLQICKAMAYLESINCVHRDIAVRNILVASPEC------VK 310
G Y E K++ + ++ +L+ +Q Y+ + VHRD+ N+L EC +K
Sbjct: 449 GQYTE--KDAARAISDILHGVQ------YIHANGVVHRDLKPENLLY---ECMTDDSKLK 595
Query: 311 LGDFGLSRYIEDEDYYKASVTRLPIKWMSPESINFRRFTTASDVWMFAVCMWEILSFGKQ 370
L DFGLSR IE E ++V P + +PE + ++T + D+W V + IL G +
Sbjct: 596 LADFGLSRIIEPE-VQMSTVCGTP-GYCAPEVLKGDKYTPSVDMWSVGVIAY-ILLCGYE 766
Query: 371 PFF 373
PFF
Sbjct: 767 PFF 775
>19761
Length = 473
Score = 51.2 bits (121), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 38/132 (28%), Positives = 65/132 (49%), Gaps = 9/132 (6%)
Frame = -3
Query: 272 LVLYSLQICKAMAYLESINCV--HRDIAVRNILVASPECVKLGDFGLSRYIED-EDYYKA 328
+V + +Q A+ Y+ + V HRD+ +NI V V+LGD GL+R + D+ +
Sbjct: 417 IVCWLMQTASALNYMHTHTPVILHRDLKPQNIYVTEKGDVRLGDLGLARKLTGPADFATS 238
Query: 329 SVTRLPIKWMSPESINFRRFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVL---- 384
V I ++SPE ++ + + + SD+W ++I GK+ D +GV+
Sbjct: 237 QVGT--IMYLSPEILSQQPYNSKSDIWSLGCVFYDIT--GKK------GSDEMGVMFLLV 88
Query: 385 --EKGDRLPKPD 394
G +LP PD
Sbjct: 87 QVMGGRKLPLPD 52
>13212
Length = 1067
Score = 50.8 bits (120), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 43/188 (22%), Positives = 79/188 (42%), Gaps = 10/188 (5%)
Frame = -1
Query: 245 WIIMELYP---YGELGHYLERNKNSLKVLTLVLYSLQICKAMAYLESINCVHRDIAVRNI 301
W I++++ +G L + + + + ++C A+ +L + +HRDI N+
Sbjct: 1064 WXIVDVFRVLWWGALDSIMVDLEKPMTEAQICYVCHEMCMALDFLHRHHVIHRDIKAGNV 885
Query: 302 LVASPECVKLGDFGLSRYIEDEDYYKASVTRLPIKWMSP-----ESINFRRFTTASDVWM 356
L+ VKL DFG+S + + P WM+P E++ + +D+W
Sbjct: 884 LLTIDGEVKLADFGVSAKNTQTQQKRDTFIGTPY-WMAPEVVLCETLKDTPYDFKADIWS 708
Query: 357 FAVCMWEILSFGKQPFFWLENKDVIGVLEKGD--RLPKPDLCPPVLYTLMTRCWDYDPSD 414
V + E + P + V+ + K D L KP + + +C DP+
Sbjct: 707 LGVTLIEFAQI-EPPNKEMHPMRVLIKIHKSDPPTLEKPKKWTKLFKDFIAKCLVKDPNL 531
Query: 415 RPRFTELV 422
RP EL+
Sbjct: 530 RPTAAELL 507
>01707
Length = 757
Score = 50.8 bits (120), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 41/156 (26%), Positives = 70/156 (44%), Gaps = 3/156 (1%)
Frame = +1
Query: 214 KEKFMSEAVIMKNLDHPHIVKLIGIIEEEPTWIIMELYPYGELGHYLERNKNSLKVLTLV 273
K+ M E ++K L HP++V+LI + + ++ Y L + L+R L +
Sbjct: 193 KKIAMREIRMLKQLKHPNLVRLIEVFRRKKRLHLVFDYVDHTLLNELDRYPRGLPEPMVK 372
Query: 274 LYSLQICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSRYIE--DEDYYKASVT 331
Q A+ + N +HRD+ NIL+ VKL DFG +R + ++Y T
Sbjct: 373 RIIYQTLLAVNFCHQYNTIHRDVKPENILITRQGQVKLCDFGFARILTGPGDEYTDYVAT 552
Query: 332 RLPIKWMSPE-SINFRRFTTASDVWMFAVCMWEILS 366
R + +PE + ++ DVW E+L+
Sbjct: 553 RW---YRAPELLVGDTQYGPPVDVWAIGCVFAELLT 651
>14126
Length = 1265
Score = 50.4 bits (119), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 55/208 (26%), Positives = 93/208 (44%), Gaps = 26/208 (12%)
Frame = +3
Query: 207 KDCTLDNKEKFM-----SEAVIMKNLD---HPHIVKLIG-----IIEEEPTWIIMELYPY 253
K L+N E+ M E ++K L+ HP++V+L+ I + E ++ Y
Sbjct: 285 KRIRLNNTEEGMPMMAIREISMLKQLEQYEHPNVVRLLDVSHNTITDREIRLNLVFEYIE 464
Query: 254 GELGHYLER------NKNSLKVLTLVLYSLQICKAMAYLESINCVHRDIAVRNILVASPE 307
+L YL + + +K L L Q+ + +L S VHRD+ +N+L++
Sbjct: 465 HDLATYLAKCPSPGLGPDRIKDLML-----QLLNGVDFLHSNRIVHRDLKPQNLLISKDG 629
Query: 308 CVKLGDFGLSRYIEDEDYYKASVTRLPIKWM-SPESINFRRFTTASDVWMFAVCMWEILS 366
+KL DFGL+R ++ A T + W SPE + + T+ D+W E+ +
Sbjct: 630 RLKLADFGLARIYS---FHMALTTVVVTLWYRSPEVLMQAEYGTSVDIWSCGCIFAELFT 800
Query: 367 F-----GKQPFFWLENK-DVIGVLEKGD 388
G F L+ +VIG+ GD
Sbjct: 801 RRALFKGSSEFDQLKKIFEVIGLPPAGD 884
>25550
Length = 941
Score = 49.7 bits (117), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 27/98 (27%), Positives = 53/98 (54%), Gaps = 3/98 (3%)
Frame = +3
Query: 356 MFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTRCWDYDPSDR 415
M A +W++ G ++ +V +LE+G R+ +P P +Y LM +CW +DP +R
Sbjct: 12 MGACDIWDVXYPG------VDLTEVYHLLERGYRMERPQGTPADVYILMLKCWQWDPKER 173
Query: 416 PRFTELVCSLSDVYQ---MEKDIAMEQERNARYRTPKI 450
P F E+ L ++++ + +++ E E+N + P +
Sbjct: 174 PTFKEIHYLLENMFEKSSISEEVEKELEKNDKKLIPTL 287
>18484
Length = 635
Score = 49.3 bits (116), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 25/114 (21%), Positives = 58/114 (50%)
Frame = +1
Query: 259 YLERNKNSLKVLTLVLYSLQICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSR 318
Y + + K Y+ +I + +L ++RD+ + N+++ S +K+ DFG+ +
Sbjct: 10 YRIQQEGKFKEPVAAFYAAEIAVGLFFLHDQGIIYRDLKLDNVMLDSEGHIKIADFGMCK 189
Query: 319 YIEDEDYYKASVTRLPIKWMSPESINFRRFTTASDVWMFAVCMWEILSFGKQPF 372
D + P +++PE + ++ ++ + D W + V ++E+L+ G+ PF
Sbjct: 190 EGMTGDATTRTFCGTP-DYIAPEIVLYQPYSKSVDWWAYGVLLFEMLA-GQPPF 345
>00715
Length = 1788
Score = 48.9 bits (115), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 50/249 (20%), Positives = 100/249 (40%), Gaps = 36/249 (14%)
Frame = +1
Query: 214 KEKFMSEAVIMK-NLDHPHIVKLIGIIE----EEPTWIIMELYPYGELGHYLERNKNSLK 268
++ + +E + + L H ++V ++G E+ W+ ME L L ++ +
Sbjct: 55 RQSYSNELLAFRCGLRHVNVVSILGATSLHRFEDGAWLAMEYVGPLNLQTILNDHQQDID 234
Query: 269 VLTLVLYSLQICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSRYI-------- 320
+ +LQ+ + + YL SIN VH D+ N L+ +++ DFG +
Sbjct: 235 SSMRLSLALQMARGLHYLHSINIVHLDLKPANCLLTRDLKLRIADFGCCHQLTPTGLDMG 414
Query: 321 EDEDYYKASVTRL-------------PIKWMSPESINFRRFTTASDVWMFAVCMWEILSF 367
E E + L + + +PE + + + SDV+ + +W++ +
Sbjct: 415 EREGGMAGNELELTPVQGAWKNELAGTLAYRAPELLKGLQPSVRSDVYSLGITLWQMCTR 594
Query: 368 GKQPFFWLENKDVIGVLEKGDRLPKPDLCPP----------VLYTLMTRCWDYDPSDRPR 417
+ P+ + V+ + D P CPP + L T+CW DRP
Sbjct: 595 -QGPYEGVPAHAVVYQVVSKDLRP----CPPPSTEDDPFEVMFRDLYTQCWARRVEDRPT 759
Query: 418 FTELVCSLS 426
++V ++
Sbjct: 760 SLDVVHAIG 786
>01756
Length = 1858
Score = 48.9 bits (115), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 57/233 (24%), Positives = 93/233 (39%), Gaps = 22/233 (9%)
Frame = -3
Query: 207 KDCTLDN-KEKF----MSEAVIMKNLDHPHIVKLIGIIEEEPTWIIMELYPYGELGHYLE 261
K +DN KE F + E I++ L+H ++V LI I + T + + + E
Sbjct: 1649 KKVLMDNEKEGFPITALREIKILQLLNHENVVDLIEICSTKATSANRYKSMFYLVFEFCE 1470
Query: 262 RNKNSLKVLTLVLYSL--------QICKAMAYLESINCVHRDIAVRNILVASPECVKLGD 313
+ L V+++L Q+ + Y+ +HRD+ NIL+ +KL D
Sbjct: 1469 HDLAGLLSNMSVVFNLPEIKEVMKQLMNGLYYIHRNKILHRDMKAANILITKQGVLKLAD 1290
Query: 314 FGLSRY----IEDEDYYKASVTRLPIKWMSPESINF--RRFTTASDVWMFAVCMWEILSF 367
FGL+R + + Y V L W P + R ++TA D W M E+
Sbjct: 1289 FGLARAFSVNLRQPNRYTNRVVTL---WYRPPELLLGDRNYSTAIDQWGAGCIMAEM--- 1128
Query: 368 GKQPFFWLENKDVIGVLEKGDRLPKPDLC---PPVLYTLMTRCWDYDPSDRPR 417
W N + G E+ LC P ++ + R Y+ D P+
Sbjct: 1127 ------WTRNPIMQGTTEQNQLTLITQLCGSITPEVWPGVERLELYNSLDLPQ 987
>12672
Length = 773
Score = 47.0 bits (110), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 38/158 (24%), Positives = 63/158 (39%), Gaps = 16/158 (10%)
Frame = +3
Query: 280 CKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSRYI---EDEDYYKASVTRLPIK 336
+ YL VHRDI NIL+ S K+GDF E + ASV
Sbjct: 21 ASGIQYLNDNGHVHRDIKTANILLDSEYTAKVGDFATVVSAPSGEGKTVQNASVVIGTAA 200
Query: 337 WMSPESINFRRFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPK---- 392
+++PE+I+F +T D + F V + E+++ + E + + + + P+
Sbjct: 201 YLAPEAIHF-DVSTKLDSYSFGVVLLEVITGLVAQDYSREERTLSSHIMENVEEPEEIHD 377
Query: 393 ---------PDLCPPVLYTLMTRCWDYDPSDRPRFTEL 421
PD LY + RC + RP ++
Sbjct: 378 FVDQSAGTWPDGAVDKLYDISMRCLNLSKKQRPNVKDI 491
>32264
Length = 287
Score = 45.4 bits (106), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 21/45 (46%), Positives = 26/45 (57%)
Frame = +1
Query: 384 LEKGDRLPKPDLCPPVLYTLMTRCWDYDPSDRPRFTELVCSLSDV 428
+E G RL + P +Y LM RCW+Y P RP F EL SL D+
Sbjct: 1 IEDGYRLQQNPQTPDSVYKLMLRCWEYVPEKRPHFKELYTSLKDI 135
>26711
Length = 405
Score = 44.7 bits (104), Expect = 1e-04, Method: Composition-based stats.
Identities = 30/99 (30%), Positives = 52/99 (52%), Gaps = 4/99 (4%)
Frame = -2
Query: 278 QICKAMAYLESINCVHRDIAVRNILVASP--ECVKLGDFGLSR--YIEDEDYYKASVTRL 333
Q+ + ++ + VH D+ N+L++ + V+L DFGL+R Y E +
Sbjct: 392 QVLDILQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARKLYPPQETFLNHGTP-- 219
Query: 334 PIKWMSPESINFRRFTTASDVWMFAVCMWEILSFGKQPF 372
+ SPE+++ + +TASDVW V + +LS G+ PF
Sbjct: 218 --GFTSPEALDVKPISTASDVWGVGVLAYILLS-GQSPF 111
>01060
Length = 1800
Score = 44.7 bits (104), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 41/163 (25%), Positives = 76/163 (46%), Gaps = 7/163 (4%)
Frame = +1
Query: 218 MSEAVIMKNLDHPHIVKLIGII-EEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVL-- 274
+ E +++ L H +IV L +I E+E +++ E +L Y+++ + VL L
Sbjct: 214 IREIAMLRELRHTNIVCLEDVIMEDERLFLVFEFLSM-DLKMYIDKFPEGV-VLDRRLVK 387
Query: 275 -YSLQICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSRYIE--DEDYYKASVT 331
Y QI + + VHRD+ +N+L+ +K+ DFG++R Y VT
Sbjct: 388 SYVFQIVTGIXFCHQRRIVHRDLKPQNLLINHTGAIKIADFGMARTFALPVRAYTHEVVT 567
Query: 332 RLPIKWMSPESI-NFRRFTTASDVWMFAVCMWEILSFGKQPFF 373
+ + +PE + +++T DVW ++L + P F
Sbjct: 568 ---LWYRAPEILMGASKYSTPVDVWSIGTIFADMLI--RTPIF 681
>04591
Length = 1117
Score = 44.3 bits (103), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 27/92 (29%), Positives = 42/92 (45%), Gaps = 3/92 (3%)
Frame = -2
Query: 278 QICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSR-YIEDEDYYKASVTRLPIK 336
Q+ + Y+ + +HRDI NIL+ +KL DFGLSR +++ K R+
Sbjct: 873 QLLNGLFYIHTKQILHRDIKAANILLTRDGVLKLADFGLSRPWVKS----KRLTNRVVTL 706
Query: 337 WMSPESINF--RRFTTASDVWMFAVCMWEILS 366
W P + R + D+W M E+ S
Sbjct: 705 WYRPPELLLGEREYGPEIDMWGVGCIMAEMWS 610
>03240
Length = 1683
Score = 43.5 bits (101), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 38/140 (27%), Positives = 66/140 (47%), Gaps = 9/140 (6%)
Frame = -3
Query: 201 AVKTCKKDCTLDNKE--KFMSEAVIMKNLDHPHIVKLIGIIEEEP-TWIIMELYPYGELG 257
A+KT +K L + +E I+ D+ +VKL ++ + +M+ P G+L
Sbjct: 1204 AMKTLRKSDVLKRNQVAHVKAERDILAEADNEWVVKLYYSFQDHNYLYFVMDYVPGGDLM 1025
Query: 258 HYLERNKNSLKVLTLVL---YSLQICKAMAYLESINCVHRDIAVRNILVASPECVKLGDF 314
L R +++L L Y ++ +A+ + + +HRDI NIL+ +KL DF
Sbjct: 1024 GLLIR----MEILDEPLARFYVAELVQAIESVHRMGFIHRDIKPDNILIDRNGHIKLTDF 857
Query: 315 GLS---RYIEDEDYYKASVT 331
GL R+ + YY+ T
Sbjct: 856 GLCTGFRWTHNSKYYQRDGT 797
>01966
Length = 1735
Score = 42.0 bits (97), Expect = 7e-04, Method: Compositional matrix adjust.
Identities = 38/159 (23%), Positives = 73/159 (45%), Gaps = 9/159 (5%)
Frame = -1
Query: 193 HKGEKINVAVKTCKKDCTLDN-KEKFMSEAVIMKNLDHPHIVKLIGII-EEEPTWIIMEL 250
H+ +A+K + + D + E +++ L H +IV L +I E+E +++ E
Sbjct: 1648 HRATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTNIVCLEDVIMEDERLFLVFEF 1469
Query: 251 YPYGELGHYLERNKNSLKVLTLVL--YSLQICKAMAYLESINCVHRDIAVRNILVASPEC 308
+L Y+++ + + ++ Y QI + + VHRD+ +N+L+
Sbjct: 1468 LSM-DLKMYIDKFPEGVVLDRRLVKSYVFQIVTGINFCHQRRIVHRDLKPQNLLINHTGA 1292
Query: 309 VKLGDFGLSRY--IEDEDYYKASVT---RLPIKWMSPES 342
+K+ DFG++R + Y VT R P M P+S
Sbjct: 1291 IKIADFGMARTFALPVRAYTHEVVTLWYRAPEILMGPQS 1175
>04138
Length = 800
Score = 42.0 bits (97), Expect = 7e-04, Method: Compositional matrix adjust.
Identities = 45/177 (25%), Positives = 71/177 (40%), Gaps = 7/177 (3%)
Frame = +1
Query: 283 MAYLESINCVHRDIAVRNILVASPECVKLGDFGLSRY----IEDEDYYKASVTRLPIKWM 338
+ Y+ +HRD+ NIL+ +KL DFGL+R + + Y V L W
Sbjct: 52 LYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTL---WY 222
Query: 339 SPESINF--RRFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLC 396
P + R ++TA D W M E+ W N + G E+
Sbjct: 223 RPPELLLGDRNYSTAIDQWGAGCIMAEM---------WTRNPIMQGTTEQNQ-------- 351
Query: 397 PPVLYTLMTR-CWDYDPSDRPRFTELVCSLSDVYQMEKDIAMEQERNARYRTPKILE 452
TL+T+ C P P T+ LS +Q++ +A ++ R R +IL+
Sbjct: 352 ----LTLITQLCGSITPEVWPGVTQ----LSMYHQIKGALAAGRKNIIRDRFARILK 498
>35671
Length = 567
Score = 41.6 bits (96), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 18/50 (36%), Positives = 29/50 (58%)
Frame = -3
Query: 385 EKGDRLPKPDLCPPVLYTLMTRCWDYDPSDRPRFTELVCSLSDVYQMEKD 434
+KG+RL KP C Y +M +CW +RP F +LV + ++Y+ +D
Sbjct: 565 QKGNRLAKPISCTDEAYKVMLQCWTESREERPTFKKLVPVMENLYRSHRD 416
>07933
Length = 728
Score = 39.3 bits (90), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 14/29 (48%), Positives = 20/29 (68%)
Frame = +3
Query: 393 PDLCPPVLYTLMTRCWDYDPSDRPRFTEL 421
P+ CP +LY +M +CW +PS RP F +L
Sbjct: 3 PNYCPNLLYNIMMQCWSAEPSARPTFHKL 89
>07836
Length = 1478
Score = 38.5 bits (88), Expect = 0.008, Method: Compositional matrix adjust.
Identities = 47/162 (29%), Positives = 73/162 (45%), Gaps = 24/162 (14%)
Frame = -1
Query: 227 LDHPHIVKLIGI-IEEEPTW----IIMELYPYGELGHYL-ERNKNSLKVLTLVLYSLQIC 280
L H +I+ I I+ +W +I + + G L YL R +S ++L L +S
Sbjct: 1394 LRHENILGFIAADIKGTGSWTQLFLITDYHENGSLHDYLLSRVLDSSEMLALA-HSAICG 1218
Query: 281 KAMAYLESINC------VHRDIAVRNILVASPECVKLGDFGLS-RYIEDEDYYKASVTRL 333
A ++E HRDI +NILV + D GL+ RYI + + + V
Sbjct: 1217 LAHLHIEIFGTRGKPAIAHRDIKSKNILVKKNGTCCIADLGLAVRYISESN--EVDVAPN 1044
Query: 334 P----IKWMSPESI-------NFRRFTTASDVWMFAVCMWEI 364
P ++M+PE + NF F A D++ F + MWEI
Sbjct: 1043 PRQGTKRYMAPEVLEMLLNVKNFDAFKQA-DMYAFGLVMWEI 921
>32359
Length = 928
Score = 37.4 bits (85), Expect = 0.015, Method: Compositional matrix adjust.
Identities = 30/103 (29%), Positives = 51/103 (49%), Gaps = 10/103 (9%)
Frame = -1
Query: 200 VAVKTCKKDCTLDNKEKFMSEAVIMKNLDHPHIVKLIGII-------EEEPTWIIMELYP 252
VA+K +D N+E IM+ L+H +IVKL +E +++E P
Sbjct: 346 VAIKKVLQDKRFKNRE-----LQIMRKLEHQNIVKLKFFFYSSGEKKDEVFLNLVLEYVP 182
Query: 253 ---YGELGHYLERNKNSLKVLTLVLYSLQICKAMAYLESINCV 292
Y HY ++K ++ +L + LY Q+ +++AY+ S CV
Sbjct: 181 ETVYRVARHY-SKSKQTIPILYIKLYMYQLFRSLAYIHSQACV 56
>28157
Length = 400
Score = 37.0 bits (84), Expect = 0.024, Method: Compositional matrix adjust.
Identities = 34/127 (26%), Positives = 59/127 (46%), Gaps = 8/127 (6%)
Frame = +3
Query: 199 NVAVKTCKKDCTLDNKEKFMSEAVIMKNLDHPHIVKLIGIIEEEPTWIIMELYPYGELGH 258
+VAVK + + K+ FM E + + HP+IV L G + P ++ME G L +
Sbjct: 6 DVAVKRIESE---QEKKSFMQELKQLSRVSHPNIVCLYGACRDHPVCLVMEYAEGGSLYN 176
Query: 259 YLERN--KNSLKVLTLVLYSLQICKAMAYLESIN---CVHRDIAVRNILVASPEC---VK 310
L + + + + LQ + YL + +HRD+ N+L+ +C +K
Sbjct: 177 VLHGSGPQPQYTAAHAMNWLLQCALGVEYLHGMKPKALIHRDLKPPNLLLI--QCGTKLK 350
Query: 311 LGDFGLS 317
+ DFG +
Sbjct: 351 ICDFGTA 371
>15741
Length = 402
Score = 35.0 bits (79), Expect = 0.079, Method: Composition-based stats.
Identities = 14/44 (31%), Positives = 24/44 (54%)
Frame = -3
Query: 259 YLERNKNSLKVLTLVLYSLQICKAMAYLESINCVHRDIAVRNIL 302
+L N L ++L + + MA++ + VHRD+A RN+L
Sbjct: 133 FLTSTANDLTARDFFSFALHVARGMAHVANNKIVHRDVAARNVL 2
>01392
Length = 1806
Score = 35.0 bits (79), Expect = 0.095, Method: Compositional matrix adjust.
Identities = 34/129 (26%), Positives = 55/129 (42%), Gaps = 12/129 (9%)
Frame = -1
Query: 257 GHYLERNKNSLKVLTLVLYSLQICKAMAYLESINCVHRDIAVRNILVASPEC---VKLGD 313
GH ER + L I +A+ +L S HRD+ NIL + VK+ D
Sbjct: 1806 GHLCEREAS--------LVVRHIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICD 1651
Query: 314 FGLSRYIE-DEDYYKASVTRLPI---KWMSPESINF-----RRFTTASDVWMFAVCMWEI 364
F L+ I D D K P+ ++M+PE ++ + D+W + ++ I
Sbjct: 1650 FDLASGISCDGDGTKTPELLTPVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILY-I 1474
Query: 365 LSFGKQPFF 373
+ G PF+
Sbjct: 1473 MLCGYPPFY 1447
>38046
Length = 446
Score = 33.9 bits (76), Expect = 0.20, Method: Composition-based stats.
Identities = 16/32 (50%), Positives = 20/32 (62%)
Frame = -1
Query: 279 ICKAMAYLESINCVHRDIAVRNILVASPECVK 310
I AMAY+E N +HR++ RNILV VK
Sbjct: 98 IADAMAYMEKENFIHRNLGDRNILVGPNNRVK 3
>27287
Length = 514
Score = 33.5 bits (75), Expect = 0.26, Method: Compositional matrix adjust.
Identities = 14/34 (41%), Positives = 19/34 (55%)
Frame = -2
Query: 392 KPDLCPPVLYTLMTRCWDYDPSDRPRFTELVCSL 425
KP ++ +M CW DP+DRP F+ LV L
Sbjct: 507 KPPYASSEMFGIMHSCWQEDPNDRPSFSRLVQEL 406
>16708
Length = 1397
Score = 32.0 bits (71), Expect = 0.76, Method: Compositional matrix adjust.
Identities = 28/112 (25%), Positives = 46/112 (41%), Gaps = 7/112 (6%)
Frame = -1
Query: 246 IIMELYPYGELGHYLERNKN-------SLKVLTLVLYSLQICKAMAYLESINCVHRDIAV 298
I++ Y G L + KN S + + +C A+ ++ + VH D+
Sbjct: 1184 ILLHFYEMGPLCNVYAHYKNKEMPIRWSNPAMVCCIAGQXVC-ALEHIHELGVVHMDVKA 1008
Query: 299 RNILVASPECVKLGDFGLSRYIEDEDYYKASVTRLPIKWMSPESINFRRFTT 350
N+LV + KL D+G+++ YK V P + S N R F T
Sbjct: 1007 DNVLVDAHGNCKLTDYGIAQ------LYK--VYPAPTETHSSGCTNKRTFYT 876
>26560
Length = 398
Score = 31.6 bits (70), Expect = 0.92, Method: Composition-based stats.
Identities = 24/99 (24%), Positives = 44/99 (44%)
Frame = -1
Query: 274 LYSLQICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVTRL 333
Y+ ++ + ++ S V+RD+ NIL+ V++ D GL+ + + + T
Sbjct: 344 FYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGLACDFSKKRPHASVGTH- 168
Query: 334 PIKWMSPESINFRRFTTASDVWMFAVCMWEILSFGKQPF 372
+M+PE + + +S W CM L G PF
Sbjct: 167 --GYMAPEVLMKGQSYDSSADWFSFGCMLYKLLKGHSPF 57
>21433
Length = 590
Score = 31.2 bits (69), Expect = 1.1, Method: Composition-based stats.
Identities = 23/91 (25%), Positives = 38/91 (41%)
Frame = +2
Query: 275 YSLQICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVTRLP 334
Y Q+ A+ Y +HRDI N+L+ +K+ DFG S + T
Sbjct: 182 YIYQLSSALEYCHYRKVIHRDIKPENLLLGLKGDLKIADFGWSVHAPSSRRTTMCGT--- 352
Query: 335 IKWMSPESINFRRFTTASDVWMFAVCMWEIL 365
+ ++ PE + + D+W V +E L
Sbjct: 353 LDYLPPEMVEGKTHDENVDLWSLGVLCYEFL 445
>37602
Length = 804
Score = 30.4 bits (67), Expect = 2.2, Method: Compositional matrix adjust.
Identities = 15/34 (44%), Positives = 18/34 (52%)
Frame = -1
Query: 281 KAMAYLESINCVHRDIAVRNILVASPECVKLGDF 314
K + YL +HRDI NIL+ VKL DF
Sbjct: 186 KGLHYLHRRGKMHRDIKGANILLTEEGDVKLADF 85
>26009
Length = 886
Score = 29.6 bits (65), Expect = 3.2, Method: Compositional matrix adjust.
Identities = 11/30 (36%), Positives = 19/30 (63%)
Frame = +3
Query: 278 QICKAMAYLESINCVHRDIAVRNILVASPE 307
Q+ A+ ++ S VHRDI N+L+ +P+
Sbjct: 735 QLVSALDFMHSKQLVHRDIKPENVLILTPD 824
>33319
Length = 382
Score = 29.6 bits (65), Expect = 3.3, Method: Composition-based stats.
Identities = 20/74 (27%), Positives = 30/74 (40%), Gaps = 2/74 (2%)
Frame = +2
Query: 525 WLRQEEKSLDPMVYMNDKSPLTPEK--EVGYRECSRPSSGGFLLAPCAEPPSLPTAQGRE 582
W +L P K P PE + G R+ P SGG A + PP+ P+ G
Sbjct: 26 WPSAPNPNLSPSWPAQIKVPPAPELPLQAGARDSPHPKSGGKKRATASAPPAQPSGPGPG 205
Query: 583 QRSLSAFPAASAMI 596
A P+ + ++
Sbjct: 206 AAVDGAAPSGTGLV 247
>02638
Length = 1490
Score = 29.6 bits (65), Expect = 3.4, Method: Compositional matrix adjust.
Identities = 24/92 (26%), Positives = 42/92 (45%), Gaps = 4/92 (4%)
Frame = +1
Query: 335 IKWMSPESINFRRFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEK----GDRL 390
I +M+PE + + A DVW M E+ + + P+ + + + ++ K D
Sbjct: 28 IAFMAPEVLRGESYGRACDVWSVGCVMIEMCT-CRPPWNSHDISNHLALIFKIASSVDPP 204
Query: 391 PKPDLCPPVLYTLMTRCWDYDPSDRPRFTELV 422
P P+ P + LM RC + D RP +L+
Sbjct: 205 PIPENMSPPVRDLMLRCLEQDSDFRPSAKDLL 300
>00302
Length = 927
Score = 29.3 bits (64), Expect = 5.3, Method: Compositional matrix adjust.
Identities = 14/43 (32%), Positives = 24/43 (55%)
Frame = -2
Query: 282 AMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDED 324
+ YL+S+ C+H+ + LVA+ VK F ++R + ED
Sbjct: 461 VLVYLDSV-CIHKSVVYEKCLVATDISVKYRLFTIARLVAPED 336
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000332816 | hsapiens_gene_ensembl | Protein
tyrosine kinase 2 beta (EC 2.7.10.2) (Focal adhesion kinase 2) (FADK
2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK
beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion
focal tyrosine kinase) (RAFTK). [Source:Uniprot/SWISSPROT;Acc:Q14289]
(1009 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
06405 202 5e-52
21808 179 6e-45
09007 166 3e-41
04852 162 8e-40
11780 94 6e-36
07291 127 2e-29
17300 120 3e-29
20640 125 7e-29
07940 117 3e-26
14116 113 4e-25
18996 111 1e-24
22005 90 1e-23
08294 106 4e-23
14477 88 2e-17
13305 86 1e-16
17637 85 2e-16
17253 83 6e-16
12721 77 3e-14
01718 77 4e-14
18921 72 1e-12
19301 69 1e-11
27546 66 9e-11
14420 65 1e-10
13066 60 3e-09
00300 59 7e-09
31885 59 9e-09
07833 58 2e-08
30755 56 8e-08
21079 55 2e-07
29581 54 3e-07
19094 53 5e-07
15910 52 1e-06
19761 52 2e-06
01707 51 3e-06
14126 50 5e-06
18484 50 6e-06
13212 50 6e-06
25550 49 8e-06
00715 49 1e-05
01756 48 2e-05
12672 46 6e-05
32264 45 1e-04
26711 45 1e-04
01060 44 2e-04
04591 44 2e-04
03240 43 5e-04
04138 42 0.001
35671 42 0.002
01966 41 0.002
07933 39 0.008
07836 38 0.018
28157 37 0.035
32359 37 0.050
15741 35 0.14
01392 35 0.19
38046 34 0.39
27287 33 0.44
21433 32 1.5
26560 32 1.7
16708 31 2.2
37602 30 4.8
00302 30 5.4
26009 29 7.7
02638 29 8.6
>06405
Length = 1965
Score = 202 bits (514), Expect = 5e-52, Method: Compositional matrix adjust.
Identities = 100/254 (39%), Positives = 153/254 (60%), Gaps = 5/254 (1%)
Frame = +1
Query: 454 VAVKTCKKDCTLDNKEKFMSEAVIMKNLDHPHIVKLIGIIEEEPT-WIIMELYPYGELGH 512
VAVKT K+D N F+ EA IMK + HP++V+L+G+ EP +I+ E P+G L
Sbjct: 343 VAVKTLKEDTMALND--FLEEAAIMKEMKHPNLVQLLGVCTREPPFYIVTEFMPHGNLLD 516
Query: 513 YLERNKNSLKVLTLVLY-SLQICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLS 571
YL + T ++Y + QI MAYLE+ N +HRD+A RN LVA VK+ DFGL+
Sbjct: 517 YLRSSTREENGPTALMYMATQIASGMAYLETKNFIHRDLAARNCLVADSNMVKVADFGLA 696
Query: 572 RYIEDEDYYKASVTRLPIKWMSPESINFRRFTTASDVWMFAVCMWEILSFGKQPFFWLEN 631
R ++D+ Y + PIKW +PE + F RF+T SD+W F V +WE+ ++G P+ +E
Sbjct: 697 RLMKDDTYTAHIGAKFPIKWTAPEGLAFNRFSTRSDIWAFGVLLWELATYGMSPYPGVEL 876
Query: 632 KDVIGVLEKGDRLPKPDLCPPVLYTLMTRCWDYDPSDRPRFTELVCSLSDVYQME---KD 688
+V +LE+G R+ +P P +Y LM +CW +DP DRP F E+ L ++++ ++
Sbjct: 877 TEVYHLLERGYRMERPPGTPADVYILMLKCWQWDPKDRPTFKEIHFLLENMFEKSSICEE 1056
Query: 689 IAMEQERNARYRTP 702
+ E E+N + + P
Sbjct: 1057VEKELEKNDKKQMP 1098
>21808
Length = 1011
Score = 179 bits (454), Expect = 6e-45, Method: Compositional matrix adjust.
Identities = 91/220 (41%), Positives = 135/220 (61%), Gaps = 1/220 (0%)
Frame = +1
Query: 454 VAVKTCKKDCTLDNKEKFMSEAVIMKNLDHPHIVKLIGI-IEEEPTWIIMELYPYGELGH 512
VA+KT K T+D K+ F++EA IMK L HP +++L + +++P +II EL G L
Sbjct: 28 VAIKTLKSG-TMDPKD-FLAEAQIMKKLRHPKLIQLYAVCTQDDPIFIITELMKNGSLLE 201
Query: 513 YLERNKNSLKVLTLVLYSLQICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSR 572
+L+ LK+ L+ QI MAYLES N +HRD+A RNILV+ VK+ DFGL+R
Sbjct: 202 FLQGKGRVLKLPALIDIGAQIACGMAYLESQNYIHRDLAARNILVSDNNTVKIADFGLAR 381
Query: 573 YIEDEDYYKASVTRLPIKWMSPESINFRRFTTASDVWMFAVCMWEILSFGKQPFFWLENK 632
I++++Y R PIKW +PE+ N+ RFT SDVW F + + E +++G+ P+ + N
Sbjct: 382 VIKEDEYEARVGARFPIKWTAPEAANYNRFTIKSDVWSFGILLTETVTYGRVPYPGMTNA 561
Query: 633 DVIGVLEKGDRLPKPDLCPPVLYTLMTRCWDYDPSDRPRF 672
+V+ +E G R+P P CP LY +M CW + +RP
Sbjct: 562 EVLHQVEHGYRMPCPPGCPKPLYDIMLECWRKEEMERPHL 681
>09007
Length = 1440
Score = 166 bits (421), Expect = 3e-41, Method: Compositional matrix adjust.
Identities = 99/307 (32%), Positives = 163/307 (53%), Gaps = 10/307 (3%)
Frame = -1
Query: 406 PDETLRRPGGPQYGIAREDVVLNRILXXXXXXXXXXXXXTNHKGEKINVAVKTCKKDCTL 465
P + RP + I+++ V L++ L T GEK+ VAVK KD
Sbjct: 930 PVSAVVRPARGKQLISKDCVALSKSLGQGHFGTVRQAIWTAESGEKVQVAVKCLSKDKIH 751
Query: 466 DNKEKFMSEAVIMKNLDHPHIVKLIGIIEEEPTWIIM--ELYPYGELGHYLER--NKNSL 521
+ ++F+ E IM+ LDH +IV++ G++ + I++ EL P L ++ +
Sbjct: 750 KDGQEFLKETAIMQMLDHENIVRVYGVVMDNGADIMLVTELAPMRSLLECVKEVSARVDF 571
Query: 522 KVLTLVLYSLQICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSRYI-EDEDYY 580
V L +S Q+C M+YLES VHRD+A RNIL+ S VK+ D G+S + ++YY
Sbjct: 570 SVPRLCDFSQQVCDGMSYLESKRLVHRDLAARNILLFSKSKVKISDVGVSGALGAGKEYY 391
Query: 581 KASVT---RLPIKWMSPESINFRRFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGV 637
++ T + + W +PES F++ASDVW F V +WE + G QP+ L + ++
Sbjct: 390 QSQQTIHLQNAVAWCAPESFRNLCFSSASDVWAFGVLLWEFFTHGFQPWAGLNGQQIMEA 211
Query: 638 LE--KGDRLPKPDLCPPVLYTLMTRCWDYDPSDRPRFTELVCSLSDVYQMEKDIAMEQER 695
++ + RL +PDLCP Y +M +CW+ +P RP F++L +L + + I ++ +
Sbjct: 210 VDAPQSQRLEQPDLCPKEYYAVMLKCWEQEPQRRPTFSQLFLTLPQI----RPIQVKAVK 43
Query: 696 NARYRTP 702
+A TP
Sbjct: 42 DAPSSTP 22
>04852
Length = 1462
Score = 162 bits (409), Expect = 8e-40, Method: Compositional matrix adjust.
Identities = 92/255 (36%), Positives = 135/255 (52%), Gaps = 31/255 (12%)
Frame = +1
Query: 453 NVAVKTCKKDCTLDNKEKFMSEAVIMKNL----DHPHIVKLIGI-IEEEPTWIIMELYPY 507
VAVK + T ++ F+ E +MK + H +IV +G + P W+I+E
Sbjct: 25 TVAVKMLRDIVTAVEEQDFVQELQVMKAVKKMGSHINIVNFLGCCTQGGPLWVIVEFAKN 204
Query: 508 GELGHYLERNKNSLKVL------------------------TLVLYSLQICKAMAYLESI 543
G L +LE ++ + L+ Y+ QI + M +L S
Sbjct: 205 GNLRDFLESCRDGINGYGKFVSPQDPGWYTKTPGGHVIRRKNLLSYAFQIARGMEFLASR 384
Query: 544 NCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKA-SVTRLPIKWMSPESINFRRF 602
C+HRD+A RN+LV +K+ DFGLSR DYYK S RLP+KWM+PE++ R+
Sbjct: 385 KCIHRDLAARNVLVTEEHVLKIADFGLSR---TGDYYKKRSGGRLPVKWMAPEALFDMRY 555
Query: 603 TTASDVWMFAVCMWEILSFGKQPFFWLENKDVIG-VLEKGDRLPKPDLCPPVLYTLMTRC 661
TT SDVW F V +WEI S G P+ + N+++ +L+ R+P+P+L LY +M RC
Sbjct: 556 TTKSDVWSFGVVLWEIFSLGGMPYASIPNEELYSKLLDDAYRMPRPELASGNLYAIMERC 735
Query: 662 WDYDPSDRPRFTELV 676
W PSDRP F++LV
Sbjct: 736 WLNRPSDRPEFSQLV 780
>11780
Length = 1713
Score = 94.0 bits (232), Expect(2) = 6e-36, Method: Compositional matrix adjust.
Identities = 53/146 (36%), Positives = 85/146 (58%), Gaps = 2/146 (1%)
Frame = +3
Query: 454 VAVKTCK-KDCTLDNKEKFMSEAVIMKNLDHPHIVKLIGIIEEEPTWIIMELYPYGELGH 512
VA+K K KD ++ F+ EA +M +L H ++V+LIG++ E +++ E G L
Sbjct: 675 VAIKQLKDKD---RGEQSFLQEASVMTSLRHDNLVRLIGVVLGETIFLVTEFMGKGNLVE 845
Query: 513 YL-ERNKNSLKVLTLVLYSLQICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLS 571
YL R ++ + + ++ C AM YLES VHRD+A RN+LV K+ DFGL+
Sbjct: 846 YLRSRGRSVITKKDQINFATDTCAAMEYLESKRLVHRDLAARNVLVHDDGKAKVSDFGLA 1025
Query: 572 RYIEDEDYYKASVTRLPIKWMSPESI 597
++ D+ + SV + PIKW +PE++
Sbjct: 1026KF---GDFSQTSV-KFPIKWTAPEAL 1091
Score = 76.6 bits (187), Expect(2) = 6e-36, Method: Compositional matrix adjust.
Identities = 31/81 (38%), Positives = 55/81 (67%)
Frame = +1
Query: 601 RFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTR 660
+FT+ SD+W F + +WEI SFG+ P+ + DV+ +E+G R+ P+ CPP +Y++M +
Sbjct: 1102 KFTSKSDMWSFGILLWEIYSFGRVPYPRIPLTDVVMHVERGYRMEAPEGCPPEIYSIMKQ 1281
Query: 661 CWDYDPSDRPRFTELVCSLSD 681
W+ DP++RP F ++ L++
Sbjct: 1282 AWELDPNERPTFKSVLARLNN 1344
>07291
Length = 833
Score = 127 bits (319), Expect = 2e-29, Method: Compositional matrix adjust.
Identities = 61/157 (38%), Positives = 95/157 (60%), Gaps = 2/157 (1%)
Frame = +1
Query: 521 LKVLTLVLYSLQICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYY 580
L V+ L+ + QI MAYL+ + VHR++A RN +V ++L D+G++ + + YY
Sbjct: 40 LTVVQLLDFGRQIADGMAYLQEVKVVHRNLAARNCIVTEDGRLQLSDYGVTGSLFPQSYY 219
Query: 581 KA--SVTRLPIKWMSPESINFRRFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVL 638
A S R +KWM+PE+I+ F++ SDVW F V +WE+L+ G P+ +EN ++ L
Sbjct: 220 TADDSPARDLVKWMAPETIDNFHFSSKSDVWAFGVVLWELLTRGITPYPDVENSSLLPYL 399
Query: 639 EKGDRLPKPDLCPPVLYTLMTRCWDYDPSDRPRFTEL 675
++G R+ KP P +Y +MT CW+ P RP F EL
Sbjct: 400 KEGHRMKKPKQSPEPVYEMMTACWNESPEQRPDFAEL 510
>17300
Length = 480
Score = 120 bits (302), Expect(2) = 3e-29, Method: Composition-based stats.
Identities = 55/116 (47%), Positives = 76/116 (65%), Gaps = 3/116 (2%)
Frame = +1
Query: 533 ICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSRYIED---EDYYKASVTRLPI 589
I M L + VHRD+A RNILV K+ DFGLSR IE E Y ++P+
Sbjct: 1 ISSGMGXLADMGYVHRDLAARNILVNEILVCKVADFGLSREIESDTTEGAYTTKGGKIPV 180
Query: 590 KWMSPESINFRRFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLP 645
+W +PE+I +R+FT+ASDVW F V MWE++S+G++P++ N+DVI +EKG RLP
Sbjct: 181 RWTAPEAIAYRKFTSASDVWSFGVVMWEVMSYGERPYWNWSNQDVIKAVEKGYRLP 348
Score = 26.9 bits (58), Expect(2) = 3e-29, Method: Compositional matrix adjust.
Identities = 11/35 (31%), Positives = 19/35 (54%)
Frame = +2
Query: 650 CPPVLYTLMTRCWDYDPSDRPRFTELVCSLSDVYQ 684
CP L+ LM W + S RP+ + +V +L + +
Sbjct: 359 CPEALHQLMLDAWQKERSHRPKMSMVVKTLDKLIR 463
>20640
Length = 1492
Score = 125 bits (315), Expect = 7e-29, Method: Compositional matrix adjust.
Identities = 58/140 (41%), Positives = 88/140 (62%), Gaps = 1/140 (0%)
Frame = +1
Query: 546 VHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKAS-VTRLPIKWMSPESINFRRFTT 604
VHRD+A RN LV VK+ DFGL+R + DYY+ S +PI+WM E+I + +F+T
Sbjct: 10 VHRDLATRNCLVGHDLVVKISDFGLARSVHSVDYYRGSEHDAIPIRWMPLEAILYNKFST 189
Query: 605 ASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTRCWDY 664
SDVW F V +WEI +F QP++ L +++V+ +++G L P+ PP +Y LM +CW
Sbjct: 190 QSDVWSFGVVLWEIFAFALQPYYGLTHEEVVRFVKEGKVLACPERTPPPMYELMKQCWHR 369
Query: 665 DPSDRPRFTELVCSLSDVYQ 684
P+ RP F L +L +++
Sbjct: 370 RPATRPSFHTLHKTLENMHS 429
>07940
Length = 1336
Score = 117 bits (292), Expect = 3e-26, Method: Compositional matrix adjust.
Identities = 51/113 (45%), Positives = 78/113 (69%), Gaps = 4/113 (3%)
Frame = -3
Query: 518 KNSLKVLT---LVLYSLQICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSRYI 574
++ LK+LT L+ Y+ Q+ + M YL S C+HRD+A RN+LVA +K+ DFGL+R +
Sbjct: 374 QDMLKMLTPKDLISYAYQVARGMEYLASKQCIHRDLAARNVLVAEEYVLKIADFGLTRNL 195
Query: 575 EDEDYY-KASVTRLPIKWMSPESINFRRFTTASDVWMFAVCMWEILSFGKQPF 626
+ DYY K + RLP+KWM+PE++ R++T+ SDVW + V +WEI + G P+
Sbjct: 194 QQFDYYRKTTDGRLPVKWMAPEALFDRKYTSKSDVWSYGVLLWEIFTLGGNPY 36
>14116
Length = 1017
Score = 113 bits (283), Expect = 4e-25, Method: Compositional matrix adjust.
Identities = 61/185 (32%), Positives = 110/185 (59%), Gaps = 6/185 (3%)
Frame = -1
Query: 448 KGEKINVAVKTCKKDCTLDNK-EKFMSEAVIMKNLDHPHIVKLIGI---IEEEPTWIIME 503
KG+ I VAVKT + + + + F+ EA+IMK+ H +++ LIGI +++ P +++
Sbjct: 555 KGD-ILVAVKTLHNNNPREIELQSFLQEALIMKDFHHSNVLTLIGICLNLDDMPL-VVLP 382
Query: 504 LYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYLESINCVHRDIAVRNILVASPECV 563
+G+L Y+ +++ + L++Y + I + M YL + VHRD+A RN ++ V
Sbjct: 381 FMKHGDLLTYIRDDQHQPTIKDLIMYGVDIARGMDYLAGLKFVHRDLAARNCMLDEDFHV 202
Query: 564 KLGDFGLSRYIEDEDYYKA--SVTRLPIKWMSPESINFRRFTTASDVWMFAVCMWEILSF 621
K+ DFGL+R I +++YY + +LP+KWM+ ES+ + + +DVW + V +WE+L+
Sbjct: 201 KVADFGLARDIYEKEYYSSENKKAKLPVKWMALESLEKGNYDSKTDVWSYGVVLWELLTR 22
Query: 622 GKQPF 626
G
Sbjct: 21 GSDAL 7
>18996
Length = 491
Score = 111 bits (278), Expect = 1e-24, Method: Compositional matrix adjust.
Identities = 57/137 (41%), Positives = 84/137 (61%), Gaps = 6/137 (4%)
Frame = +2
Query: 546 VHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVTR-LPIKWMSPESINFRRFTT 604
+HRD+A RNILV CVK+ DFGL+++ + YY R +PIKW SPE+I +F++
Sbjct: 2 IHRDLAARNILVDR-SCVKISDFGLAQFANADGYYYGISQRDIPIKWYSPEAIETCKFSS 178
Query: 605 ASDVWMFAVCMWEILSFGKQPFFW----LENKDVIGVLEKGDRLPKPDLCPPVLYT-LMT 659
SDVW + V ++E+ S G+ P L ++ + L KG+RLPKP+LC +Y+ LM
Sbjct: 179 YSDVWSYGVTLFEMFSRGEIPNLLPGHDLTQEEFLNRLRKGERLPKPELCSDFVYSELMR 358
Query: 660 RCWDYDPSDRPRFTELV 676
CW P RP F +++
Sbjct: 359 PCWHEMPKSRPTFHQII 409
>22005
Length = 873
Score = 89.7 bits (221), Expect(2) = 1e-23, Method: Compositional matrix adjust.
Identities = 64/208 (30%), Positives = 96/208 (46%), Gaps = 45/208 (21%)
Frame = +1
Query: 457 KTCKKDCTLDNKEKFMSEAVIMKNLDHPHIVKLIGIIE-EEPTWIIMELYPYGELGHYL- 514
K K+D + D + F EA +M + DHP+IVKL+G+ +P ++ E G+L +L
Sbjct: 109 KMLKEDASEDLQSDFEREASLMADFDHPNIVKLLGVCAIGKPMCLLFEFMSKGDLNDFLR 288
Query: 515 -----------------------------------------ERNKNSLKVLTLVLY-SLQ 532
+R+ + + LY S Q
Sbjct: 289 LCSPENYNLPVSRSQNLVVDLEDGLRVEVEAEECEKDTQSEDRDCSGMLXTKDQLYISQQ 468
Query: 533 ICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKAS-VTRLPIKW 591
I MAYL + VHRD+A R + + + DFGL+R + DYY+ S +PI+W
Sbjct: 469 ISAGMAYLAQKDYVHRDLATRTVXSRTT*-S*ISDFGLARSVHSVDYYRGSEQDAIPIRW 645
Query: 592 MSPESINFRRFTTASDVWMFAVCMWEIL 619
M E+I + +F+T SDVW F V +WEIL
Sbjct: 646 MPLEAILYSKFSTQSDVWSFGVVLWEIL 729
Score = 39.3 bits (90), Expect(2) = 1e-23, Method: Compositional matrix adjust.
Identities = 15/49 (30%), Positives = 28/49 (57%)
Frame = +3
Query: 619 LSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTRCWDYDPS 667
+F QP++ L +++V+ ++ G L +P P +Y LM +CW P+
Sbjct: 726 FAFALQPYYGLTHEEVVNYVKAGKILEQPTKTPHQVYELMKQCWQRRPA 872
>08294
Length = 1849
Score = 106 bits (265), Expect = 4e-23, Method: Compositional matrix adjust.
Identities = 68/210 (32%), Positives = 104/210 (49%), Gaps = 13/210 (6%)
Frame = +2
Query: 484 PHIVKLIGIIEE-EPTWIIMELYPYGELGHYL--ERNKNS----LKVLTLVL-----YSL 531
P+IV +G+ E EP ++I E +G+L +L RN N +V L L
Sbjct: 887 PNIVHFMGVCREAEPHFLITEYCDWGDLKQFLLATRNDNGRGRGTRVPALALSQKLGMGQ 1066
Query: 532 QICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVTRLPIKW 591
Q+ M L + VH D+A RN+L+ S +K+ LS + +YY +P++W
Sbjct: 1067 QVAAGMEALSNQGLVHGDLAARNVLLTSRMQLKVARPALSGDVYASEYYPLHQRLVPLRW 1246
Query: 592 MSPESINFRRFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGD-RLPKPDLC 650
+ PE + TT DVW F V +WE+L P+ + +++V+ L+ L PD
Sbjct: 1247 LPPEGVLEDSATTCGDVWAFGVFLWEVLQLADLPYRLMSDEEVLRSLQHSQAALDSPD-A 1423
Query: 651 PPVLYTLMTRCWDYDPSDRPRFTELVCSLS 680
PP L +L+ RC PS RP F+E+ LS
Sbjct: 1424 PPALLSLLQRCTAQQPSQRPPFSEICSVLS 1513
>14477
Length = 493
Score = 87.8 bits (216), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 51/134 (38%), Positives = 79/134 (58%), Gaps = 2/134 (1%)
Frame = -1
Query: 451 KINVAVKTCKK-DCTLDNKEKFMSEAVIMKNLDHPHIVKLIGIIEEEPTWIIMELYPYGE 509
+I VA+K K D + + + EA +MK +DH HIV+LIG+ E E +++EL G
Sbjct: 409 EIPVAIKVLKNADLDPSVQSELIKEAEVMKKMDHMHIVRLIGLCEGETMMLVLELAKLGP 230
Query: 510 LGHYLERNKNSLKVLTLVLYSLQICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFG 569
L +L +NK+ L + ++ Q+ + M YLE+ VHRD+A RNIL+ K+ DFG
Sbjct: 229 LNKFLPKNKH-LPLWNILELMWQVSQGMEYLEANKFVHRDLAARNILLCDEHFAKISDFG 53
Query: 570 LSRYIEDE-DYYKA 582
+S+ + E +YY A
Sbjct: 52 MSKTLSRENNYYMA 11
>13305
Length = 549
Score = 85.5 bits (210), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 42/113 (37%), Positives = 64/113 (56%), Gaps = 3/113 (2%)
Frame = +2
Query: 585 TRLPIKWMSPESINFRRFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRL 644
TR+PI+WM+ ES+ +TT SDVW F V +WEI + G P+ + + + L+ G RL
Sbjct: 5 TRVPIRWMAVESLFNNTYTTQSDVWSFGVVLWEIFTLGGTPYSSTDTQQLFAFLKDGYRL 184
Query: 645 PKPDLCPPVLYTLMTRCWDYDPSDRPRFTELVCSLS---DVYQMEKDIAMEQE 694
+P LC Y +M +CW+ + RP F EL L D Q+ +++ E+E
Sbjct: 185 KRPKLCDQNTYAMMLQCWNENAQRRPTFPELCGRLQRMLDDCQVYMNLSTEEE 343
>17637
Length = 447
Score = 84.7 bits (208), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 46/122 (37%), Positives = 68/122 (55%), Gaps = 1/122 (0%)
Frame = +1
Query: 563 VKLGDFGLSRYIEDEDYYKASVTRL-PIKWMSPESINFRRFTTASDVWMFAVCMWEILSF 621
VKL D LSR + DY PIKW+S E++ + SDVW F V MWE+ +
Sbjct: 28 VKLTDSALSRDLFSGDYNCLGDGEYRPIKWLSLEALQKSHYNEGSDVWSFGVLMWEMCTL 207
Query: 622 GKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTRCWDYDPSDRPRFTELVCSLSD 681
GK P+ ++ ++ L+ G RL +P CP L+T+M CW P++RP F++L LS+
Sbjct: 208 GKLPYAEIDPYEMEHYLKDGYRLAQPFNCPDELFTIMAYCWASMPAERPSFSQLQICLSE 387
Query: 682 VY 683
+
Sbjct: 388 FH 393
>17253
Length = 483
Score = 82.8 bits (203), Expect = 6e-16, Method: Composition-based stats.
Identities = 50/160 (31%), Positives = 83/160 (51%), Gaps = 15/160 (9%)
Frame = -1
Query: 447 HKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKNLD-HPHIVKLIGIIE-EEPTWIIMEL 504
H + VAVKT + T K +F+ E IM+ L HP++V +G +P I+ME
Sbjct: 480 HARQWDTVAVKTHNEAATDAEKSEFLRELSIMRKLPRHPNVVSFMGCCTMSDPALILMEF 301
Query: 505 YPYGELGHYLERNK-----------NSLKVLTLVLYSLQICKAMAYLESINCVHRDIAVR 553
+G+L +L + + N L ++L + + MA++ + VHRD+A R
Sbjct: 300 CCHGDLLSFLRKRRPDRTVFLTSTANDLTARDFFSFALHVARGMAHVANNKIVHRDVAAR 121
Query: 554 NILVASPECVKLGDFGLSRYIEDEDYYKASVTR--LPIKW 591
N+L++ K+ DFGLSR + D++ V+R LP++W
Sbjct: 120 NVLISERNVCKVSDFGLSRRVGDQNDVYEIVSRRPLPLRW 1
>12721
Length = 821
Score = 77.4 bits (189), Expect = 3e-14, Method: Compositional matrix adjust.
Identities = 60/233 (25%), Positives = 110/233 (47%), Gaps = 8/233 (3%)
Frame = +1
Query: 445 TNHKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKNLDHPHIVKLIG--IIEEEPTWIIM 502
T+ G ++ V +K +E +E V+M++ HP+IV++ ++ +E W++M
Sbjct: 148 TSRDGRQMAVKKMDLRKQ---QRRELLFNEVVVMRDYHHPNIVEMYNSYLVNDE-LWVVM 315
Query: 503 ELYPYGELGHYLERNK-NSLKVLTLVLYSLQICKAMAYLESINCVHRDIAVRNILVASPE 561
E G L + N+ + +++ T+ L KA+A+L + +HRDI +IL++
Sbjct: 316 EFMEGGALTDIVTNNRMDEVQIATVCRACL---KALAFLHANGVIHRDIKSDSILLSHDG 486
Query: 562 CVKLGDFGLSRYIEDEDYYKASVTRLPIKWMSPESINFRRFTTASDVWMFAVCMWEILSF 621
VKL DFG + + + S+ P WM+PE I+ + D+W + + E++
Sbjct: 487 KVKLXDFGFCAQVTQDLQKRKSLVGTPY-WMAPEVISRLPYGPEVDIWSLGIMVMEMID- 660
Query: 622 GKQPFFWLENKDVIGVLEKGDRLPKPDL-----CPPVLYTLMTRCWDYDPSDR 669
+ PFF N+ + + + +P P L P L + R DP R
Sbjct: 661 AEPPFF---NEPPLQAMRRIRDMPPPKLRNTHKISPRLQGFIDRMLVRDPHQR 810
>01718
Length = 959
Score = 77.0 bits (188), Expect = 4e-14, Method: Compositional matrix adjust.
Identities = 62/255 (24%), Positives = 110/255 (43%), Gaps = 10/255 (3%)
Frame = +3
Query: 450 EKINVAVKTCKKDCTLDNKEKFMSEAVIMKNLDHPHIVKLIGI-IEEEPTWIIMELYPYG 508
+I V K + N+ + E ++ L H +I++ +G+ + E + E P G
Sbjct: 210 HRITGQVMALKMNTMTSNRHNMLREVQLLNRLQHANILRFMGVCVHEGQLHALTEYIPSG 389
Query: 509 ELGHYLERNKNSLKVLTLVLYSLQICKAMAYLESINCVHRDIAVRNILVASPEC----VK 564
L LE+ L + +L + + + YL S +HRD+ +NIL+ +
Sbjct: 390 NLEQLLEKKDEELPWTQRIQLTLGLARGLDYLHSTRFIHRDLTSKNILIRREDNHGYHAV 569
Query: 565 LGDFGLSRYIEDE-DYYKASVTRLPIKWMSPESINFRRFTTASDVWMFAVCMWEILSFGK 623
+ DFGL+ I D D K P WM+PE +N + +D++ + M EI +
Sbjct: 570 IADFGLATKIPDPLDKEKLPTVGSPY-WMAPEVLNGHFYNERADLFSVGIIMCEITARIP 746
Query: 624 QPFFWLENKDVIGVLEKGDRLPKPDL---CPPVLYTLMTRCWDYDPSDRPRFTELVCSLS 680
+ + GV D + ++ CP L +C DP RPR E++ L
Sbjct: 747 ADPDIMPRMNNFGV----DYVALSEMISYCPLDYLQLAFKCCQVDPQKRPRGVEIIEWLE 914
Query: 681 DVYQ-MEKDIAMEQE 694
+++ ++ DI Q+
Sbjct: 915 KIFKNLKNDIFTRQQ 959
>18921
Length = 697
Score = 72.0 bits (175), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 55/183 (30%), Positives = 88/183 (48%), Gaps = 4/183 (2%)
Frame = +2
Query: 447 HKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKNLDHPHIVKLIG-IIEEEPTWIIMELY 505
HK +A+K D L ++ + E IM+ D +IVK G + WI+ME
Sbjct: 92 HKETGQVLAIKQVPVDTDL---QEIIKEISIMQQCDSKYIVKYYGSYFKNTDLWIVMEYC 262
Query: 506 PYGELGHYLE-RNKNSLK--VLTLVLYSLQICKAMAYLESINCVHRDIAVRNILVASPEC 562
G + + RNK ++ + T++ Y+L K + YL S +HRDI NIL+ +
Sbjct: 263 GAGSVSDIMRLRNKTLVEREIATILYYTL---KGLXYLHSRRKIHRDIKAGNILLNNEGH 433
Query: 563 VKLGDFGLSRYIEDEDYYKASVTRLPIKWMSPESINFRRFTTASDVWMFAVCMWEILSFG 622
KL DFG++ + D + +V P WM+PE I + +D+W + E ++ G
Sbjct: 434 AKLADFGVAGQLTDTMAKRNTVIGTPY-WMAPEVIQEIGYDCVADIWSLGITALE-MAEG 607
Query: 623 KQP 625
K P
Sbjct: 608 KPP 616
>19301
Length = 712
Score = 68.6 bits (166), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 38/95 (40%), Positives = 53/95 (55%), Gaps = 1/95 (1%)
Frame = +2
Query: 478 MKNLDHPHIVKLIGIIEEEPTW-IIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKA 536
++ L+HP+I+ G+ + P + IIME PYG+L L K L L +S QI
Sbjct: 431 LRKLNHPNIISFKGVCTQAPCYCIIMEYCPYGQLYEVLRDGKEIPPALVLD-WSKQIASG 607
Query: 537 MAYLESINCVHRDIAVRNILVASPECVKLGDFGLS 571
M YL S +HRD+ N+LVA + VK+ DFG S
Sbjct: 608 MNYLHSHKIIHRDLKSPNVLVAKNDVVKISDFGTS 712
>27546
Length = 426
Score = 65.9 bits (159), Expect = 9e-11, Method: Composition-based stats.
Identities = 42/134 (31%), Positives = 71/134 (52%), Gaps = 3/134 (2%)
Frame = -1
Query: 446 NHKGEKINVAVKTCKK-DCTLDNKEKFM-SEAVIMKNLDHPHIVKLIGIIEEEPT-WIIM 502
+ G +N+A K K +D +KF E I+ LDHP+I+++ I++ P +I M
Sbjct: 420 DESGHGVNLACKIIDKAKAPIDFVKKFFPRELEILTRLDHPNIIQIHSILQRGPKIFIFM 241
Query: 503 ELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYLESINCVHRDIAVRNILVASPEC 562
G++ ++++ + T V + Q+ KA+ YL S + HRD+ NIL++
Sbjct: 240 RYAEKGDMLSHIKKTGPIDEAQTKVWF-FQMAKALQYLHSHDIAHRDLKCENILLSKRLN 64
Query: 563 VKLGDFGLSRYIED 576
VK+ DFG +RY D
Sbjct: 63 VKIADFGFARYCRD 22
>14420
Length = 528
Score = 65.5 bits (158), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 44/162 (27%), Positives = 78/162 (48%), Gaps = 2/162 (1%)
Frame = +2
Query: 468 KEKFMSEAVIMKNLDHPHIVK-LIGIIEEEPTWIIMELYPYGELGHYL-ERNKNSLKVLT 525
KE ++E ++M+ +P+IV L + E W++ME G L + E + ++
Sbjct: 32 KELIINEILVMRENQNPNIVNYLDSYLVGEELWVVMEFLAGGSLTDVVTETCMDEGQIAA 211
Query: 526 LVLYSLQICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVT 585
+ LQ A+ +L +HRDI NIL+ VKL DFG + E ++++
Sbjct: 212 VCRECLQ---ALEFLHENQVIHRDIKSDNILLGMDGSVKLTDFGFCAQLSPEQSKRSTMV 382
Query: 586 RLPIKWMSPESINFRRFTTASDVWMFAVCMWEILSFGKQPFF 627
P WM+PE + +++ D+W V E++ G+ P+
Sbjct: 383 GTP-YWMAPEVVTRKQYGPTVDIWSLGVMCIEMIE-GEPPYL 502
>13066
Length = 551
Score = 60.5 bits (145), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 41/126 (32%), Positives = 66/126 (52%), Gaps = 3/126 (2%)
Frame = +3
Query: 449 GEKINVAVKTCKKD-CTLDNKEKFM-SEAVIMKNLDHPHIVKLIGIIEEEP-TWIIMELY 505
G I +A K K+ +D EKF E ++ LDHP+I+++ I++ P +I M
Sbjct: 45 GRNIKLACKIIDKEKAPVDFVEKFFPRELDLLTKLDHPYIIQIHSILQRXPKNFIFMRFA 224
Query: 506 PYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYLESINCVHRDIAVRNILVASPECVKL 565
G+L Y++ +K ++ Q+ A+ YL S + HRD+ NIL++S VKL
Sbjct: 225 ERGDLLTYIQE-VGFVKEKQAKIWFYQMTTALNYLHSYDVAHRDLKCENILLSSHFNVKL 401
Query: 566 GDFGLS 571
DFG +
Sbjct: 402 ADFGFA 419
>00300
Length = 2318
Score = 59.3 bits (142), Expect = 7e-09, Method: Compositional matrix adjust.
Identities = 55/218 (25%), Positives = 98/218 (44%), Gaps = 8/218 (3%)
Frame = -1
Query: 474 EAVIMKNLDHPHIVKLIGI-IEEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQ 532
E I + + H ++VK G+ + ++ + ME Y + G E K L + Y+ +
Sbjct: 1511 EIKIFEGIQHENLVKYYGVEVHKDEMLMFME---YCDTGTIEEAAKMGLPEYLIRRYTRE 1341
Query: 533 ICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVTRL--PIK 590
I A+ +L + VHRDI NI + S VKLGDFG S ++ L
Sbjct: 1340 IVLAVNHLHENSIVHRDIKGANIFLTSNGHVKLGDFGCSVKLKSHTTMPGEFHNLVGTTA 1161
Query: 591 WMSPESI---NFRRFTTASDVWMFAVCMWEILSFGKQPFFWLENK-DVIGVLEKGDRLPK 646
+M+PE + + A+D+W + E ++ GK+P+ L+N ++ + G +
Sbjct: 1160 YMAPEVFTQNDQGGYGRAADIWSLGCVVIE-MATGKRPWHDLDNNYQIMYKVGIGHKPAV 984
Query: 647 PDLCPPVLYTLMTRCWDYDPSDRPRFTELV-CSLSDVY 683
PD + +DP+ R ++L+ + + VY
Sbjct: 983 PDSLSVEGKHFLDLIMCHDPAQRALASQLLDHTFTKVY 870
>31885
Length = 529
Score = 58.9 bits (141), Expect = 9e-09, Method: Compositional matrix adjust.
Identities = 44/156 (28%), Positives = 83/156 (53%), Gaps = 6/156 (3%)
Frame = -2
Query: 477 IMKNLDHPHIVKL-IGIIEEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICK 535
++ LDHP +V L +EE +++++L+ G+L +++++ + S + + Y Q+
Sbjct: 513 MLTRLDHPFLVNLWYAFQDEEDLFMVVDLFLGGDLRYHMQQ-EVSFREDCVKFYLCQLAL 337
Query: 536 AMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVTRLPIKWMSPE 595
+ YL S VHRDI NIL+ + DF ++ +ED++ ++ P +M+PE
Sbjct: 336 VLDYLRSQKIVHRDIKPDNILLDEQGHCHVTDFNIATQLEDDELATSTSGTRP--YMAPE 163
Query: 596 ----SINFRR-FTTASDVWMFAVCMWEILSFGKQPF 626
+IN RR + D W V ++E+L ++PF
Sbjct: 162 VYGVAINERRGYGFPVDWWSLGVSLFELLK-KRRPF 58
>07833
Length = 1504
Score = 58.2 bits (139), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 52/221 (23%), Positives = 101/221 (45%), Gaps = 15/221 (6%)
Frame = -3
Query: 471 FMSEAVIMKNLDHPHIVKLIGIIEEEPTWIIM-ELYPYGELGHYLERNKNSLKVLTLVL- 528
FM E ++ +HP+++ ++ + P +++ + P+G L + L + L
Sbjct: 1478 FMEEFPRLRIFNHPNVLPVLACCNQPPNLVLISQFMPFGSLYNTLHGESGIVVDQNQSLR 1299
Query: 529 YSLQICKAMAYLESINCVHRDIAVRNILVASPEC---------VKLGDFGLSRYIEDEDY 579
+++ I + M +L S+ + + N L+ S + + D+ S + + + Y
Sbjct: 1298 FAMDIARGMEFLHSM-----EPTIPNFLLTSKHVMIDEDLTARINMADYCFSFHEKGKVY 1134
Query: 580 YKASVTRLPIKWMSPESINFRR---FTTASDVWMFAVCMWEILSFGKQPFFWLENKDV-I 635
A WM+PE++ R T A+D+W FA+ MWE L + PF L + +V +
Sbjct: 1133 SPA--------WMAPEALQRRPDDINTRAADMWSFAILMWE-LETREVPFAELSSMEVGM 981
Query: 636 GVLEKGDRLPKPDLCPPVLYTLMTRCWDYDPSDRPRFTELV 676
V +G R+ P + L+ C + +P RPRF ++
Sbjct: 980 KVALEGLRISIPPGISLHMSRLIKICMNEEPGKRPRFDMII 858
>30755
Length = 1137
Score = 55.8 bits (133), Expect = 8e-08, Method: Compositional matrix adjust.
Identities = 30/101 (29%), Positives = 55/101 (54%), Gaps = 1/101 (0%)
Frame = +2
Query: 528 LYSLQICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVTRL 587
Y +I A+ YL S ++RD+ + N+L+ +K+ DFGL + ED Y + + T
Sbjct: 44 FYGAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCK--EDITYGRTTKTFC 217
Query: 588 PI-KWMSPESINFRRFTTASDVWMFAVCMWEILSFGKQPFF 627
++++PE ++ + A D W V M+E++ G+ PF+
Sbjct: 218 GTPEYLAPEVLDDNDYGRAVDWWGTGVVMYEMIC-GRLPFY 337
>21079
Length = 878
Score = 54.7 bits (130), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 40/146 (27%), Positives = 69/146 (47%), Gaps = 3/146 (2%)
Frame = +1
Query: 483 HPHIVKLIGIIEEEPTWI-IMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYLE 541
HP ++ L E T + +ME GEL + R+ L V + QIC + Y+
Sbjct: 1 HPKLLMLWDAFEAPRTMVLVMEFVGAGELFERVIRDDFVLTERDCVHFVRQICSGVGYMH 180
Query: 542 SINCVHRDIAVRNILVASPEC--VKLGDFGLSRYIEDEDYYKASVTRLPIKWMSPESINF 599
+ + +H D+ N+L S +K+ DFGL+R+ + D V ++++PE +N+
Sbjct: 181 TQSILHLDLKPENVLCVSDNSNQIKIIDFGLARFYKPGD--SLQVLFGTPEFIAPEVVNY 354
Query: 600 RRFTTASDVWMFAVCMWEILSFGKQP 625
+D+W V + +LS G P
Sbjct: 355 DEINFTTDMWSIGVICYILLS-GLSP 429
>29581
Length = 1278
Score = 53.9 bits (128), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 43/158 (27%), Positives = 73/158 (46%), Gaps = 6/158 (3%)
Frame = -2
Query: 475 AVIMKNLDHPHIVKLIGII---EEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSL 531
+ + NL H +IV+L ++ + +++ME Y +L L+ + L
Sbjct: 1202 STFLLNLRHQNIVQLQEVVVGKSLDSLFLVME-YCEQDLASLLDNMPAPFSESQVKCIVL 1026
Query: 532 QICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSR-YIEDEDYYKASVTRLPIK 590
Q+ K + YL +HRD+ V N+L+ CVK+ DFGL+R Y + + V L
Sbjct: 1025 QLLKGLRYLHEAFIIHRDLKVSNLLMTDKGCVKIADFGLARNYGKPQKPMTPKVVTL--- 855
Query: 591 WMSPESINF--RRFTTASDVWMFAVCMWEILSFGKQPF 626
W + F + +TA D+W + E+L G +P
Sbjct: 854 WYRAPELLFGSKTHSTAIDMWSAGCILGELL--GHKPL 747
>19094
Length = 898
Score = 53.1 bits (126), Expect = 5e-07, Method: Composition-based stats.
Identities = 33/105 (31%), Positives = 54/105 (51%), Gaps = 2/105 (1%)
Frame = +1
Query: 516 RNKNSLK--VLTLVLYSLQICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSRY 573
RNK ++ + T++ Y+L K + YL S +HRDI NIL+ + KL DFG++
Sbjct: 37 RNKTLVEREIATILYYTL---KGL*YLHSRRKIHRDIKAGNILLNNEGHAKLADFGVAGQ 207
Query: 574 IEDEDYYKASVTRLPIKWMSPESINFRRFTTASDVWMFAVCMWEI 618
+ D + +V P WM+PE I + +D+W + E+
Sbjct: 208 LTDTMAKRNTVIGTPY-WMAPEVIQEIGYDCVADIWSLGITALEM 339
>15910
Length = 1361
Score = 52.0 bits (123), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 40/123 (32%), Positives = 64/123 (52%), Gaps = 6/123 (4%)
Frame = +2
Query: 511 GHYLERNKNSLKVLTLVLYSLQICKAMAYLESINCVHRDIAVRNILVASPEC------VK 564
G Y E K++ + ++ +L+ +Q Y+ + VHRD+ N+L EC +K
Sbjct: 449 GQYTE--KDAARAISDILHGVQ------YIHANGVVHRDLKPENLLY---ECMTDDSKLK 595
Query: 565 LGDFGLSRYIEDEDYYKASVTRLPIKWMSPESINFRRFTTASDVWMFAVCMWEILSFGKQ 624
L DFGLSR IE E ++V P + +PE + ++T + D+W V + IL G +
Sbjct: 596 LADFGLSRIIEPE-VQMSTVCGTP-GYCAPEVLKGDKYTPSVDMWSVGVIAY-ILLCGYE 766
Query: 625 PFF 627
PFF
Sbjct: 767 PFF 775
>19761
Length = 473
Score = 51.6 bits (122), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 38/132 (28%), Positives = 65/132 (49%), Gaps = 9/132 (6%)
Frame = -3
Query: 526 LVLYSLQICKAMAYLESINCV--HRDIAVRNILVASPECVKLGDFGLSRYIED-EDYYKA 582
+V + +Q A+ Y+ + V HRD+ +NI V V+LGD GL+R + D+ +
Sbjct: 417 IVCWLMQTASALNYMHTHTPVILHRDLKPQNIYVTEKGDVRLGDLGLARKLTGPADFATS 238
Query: 583 SVTRLPIKWMSPESINFRRFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVL---- 638
V I ++SPE ++ + + + SD+W ++I GK+ D +GV+
Sbjct: 237 QVGT--IMYLSPEILSQQPYNSKSDIWSLGCVFYDIT--GKK------GSDEMGVMFLLV 88
Query: 639 --EKGDRLPKPD 648
G +LP PD
Sbjct: 87 QVMGGRKLPLPD 52
>01707
Length = 757
Score = 50.8 bits (120), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 47/184 (25%), Positives = 84/184 (45%), Gaps = 5/184 (2%)
Frame = +1
Query: 468 KEKFMSEAVIMKNLDHPHIVKLIGIIEEEPTWIIMELYPYGELGHYLERNKNSLKVLTLV 527
K+ M E ++K L HP++V+LI + + ++ Y L + L+R L +
Sbjct: 193 KKIAMREIRMLKQLKHPNLVRLIEVFRRKKRLHLVFDYVDHTLLNELDRYPRGLPEPMVK 372
Query: 528 LYSLQICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSRYIE--DEDYYKASVT 585
Q A+ + N +HRD+ NIL+ VKL DFG +R + ++Y T
Sbjct: 373 RIIYQTLLAVNFCHQYNTIHRDVKPENILITRQGQVKLCDFGFARILTGPGDEYTDYVAT 552
Query: 586 RLPIKWMSPE-SINFRRFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEK--GD 642
R + +PE + ++ DVW E+L+ G+ + + D + ++ K GD
Sbjct: 553 RW---YRAPELLVGDTQYGPPVDVWAIGCVFAELLT-GQALWPGRSDVDQLHLIRKTLGD 720
Query: 643 RLPK 646
+P+
Sbjct: 721 LIPR 732
>14126
Length = 1265
Score = 50.1 bits (118), Expect = 5e-06, Method: Compositional matrix adjust.
Identities = 55/208 (26%), Positives = 93/208 (44%), Gaps = 26/208 (12%)
Frame = +3
Query: 461 KDCTLDNKEKFM-----SEAVIMKNLD---HPHIVKLIG-----IIEEEPTWIIMELYPY 507
K L+N E+ M E ++K L+ HP++V+L+ I + E ++ Y
Sbjct: 285 KRIRLNNTEEGMPMMAIREISMLKQLEQYEHPNVVRLLDVSHNTITDREIRLNLVFEYIE 464
Query: 508 GELGHYLER------NKNSLKVLTLVLYSLQICKAMAYLESINCVHRDIAVRNILVASPE 561
+L YL + + +K L L Q+ + +L S VHRD+ +N+L++
Sbjct: 465 HDLATYLAKCPSPGLGPDRIKDLML-----QLLNGVDFLHSNRIVHRDLKPQNLLISKDG 629
Query: 562 CVKLGDFGLSRYIEDEDYYKASVTRLPIKWM-SPESINFRRFTTASDVWMFAVCMWEILS 620
+KL DFGL+R ++ A T + W SPE + + T+ D+W E+ +
Sbjct: 630 RLKLADFGLARIYS---FHMALTTVVVTLWYRSPEVLMQAEYGTSVDIWSCGCIFAELFT 800
Query: 621 F-----GKQPFFWLENK-DVIGVLEKGD 642
G F L+ +VIG+ GD
Sbjct: 801 RRALFKGSSEFDQLKKIFEVIGLPPAGD 884
>18484
Length = 635
Score = 49.7 bits (117), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 25/114 (21%), Positives = 58/114 (50%)
Frame = +1
Query: 513 YLERNKNSLKVLTLVLYSLQICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSR 572
Y + + K Y+ +I + +L ++RD+ + N+++ S +K+ DFG+ +
Sbjct: 10 YRIQQEGKFKEPVAAFYAAEIAVGLFFLHDQGIIYRDLKLDNVMLDSEGHIKIADFGMCK 189
Query: 573 YIEDEDYYKASVTRLPIKWMSPESINFRRFTTASDVWMFAVCMWEILSFGKQPF 626
D + P +++PE + ++ ++ + D W + V ++E+L+ G+ PF
Sbjct: 190 EGMTGDATTRTFCGTP-DYIAPEIVLYQPYSKSVDWWAYGVLLFEMLA-GQPPF 345
>13212
Length = 1067
Score = 49.7 bits (117), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 43/188 (22%), Positives = 79/188 (42%), Gaps = 10/188 (5%)
Frame = -1
Query: 499 WIIMELYP---YGELGHYLERNKNSLKVLTLVLYSLQICKAMAYLESINCVHRDIAVRNI 555
W I++++ +G L + + + + ++C A+ +L + +HRDI N+
Sbjct: 1064 WXIVDVFRVLWWGALDSIMVDLEKPMTEAQICYVCHEMCMALDFLHRHHVIHRDIKAGNV 885
Query: 556 LVASPECVKLGDFGLSRYIEDEDYYKASVTRLPIKWMSP-----ESINFRRFTTASDVWM 610
L+ VKL DFG+S + + P WM+P E++ + +D+W
Sbjct: 884 LLTIDGEVKLADFGVSAKNTQTQQKRDTFIGTPY-WMAPEVVLCETLKDTPYDFKADIWS 708
Query: 611 FAVCMWEILSFGKQPFFWLENKDVIGVLEKGD--RLPKPDLCPPVLYTLMTRCWDYDPSD 668
V + E + P + V+ + K D L KP + + +C DP+
Sbjct: 707 LGVTLIEFAQI-EPPNKEMHPMRVLIKIHKSDPPTLEKPKKWTKLFKDFIAKCLVKDPNL 531
Query: 669 RPRFTELV 676
RP EL+
Sbjct: 530 RPTAAELL 507
>25550
Length = 941
Score = 49.3 bits (116), Expect = 8e-06, Method: Compositional matrix adjust.
Identities = 27/98 (27%), Positives = 53/98 (54%), Gaps = 3/98 (3%)
Frame = +3
Query: 610 MFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTRCWDYDPSDR 669
M A +W++ G ++ +V +LE+G R+ +P P +Y LM +CW +DP +R
Sbjct: 12 MGACDIWDVXYPG------VDLTEVYHLLERGYRMERPQGTPADVYILMLKCWQWDPKER 173
Query: 670 PRFTELVCSLSDVYQ---MEKDIAMEQERNARYRTPKI 704
P F E+ L ++++ + +++ E E+N + P +
Sbjct: 174 PTFKEIHYLLENMFEKSSISEEVEKELEKNDKKLIPTL 287
>00715
Length = 1788
Score = 48.5 bits (114), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 50/249 (20%), Positives = 100/249 (40%), Gaps = 36/249 (14%)
Frame = +1
Query: 468 KEKFMSEAVIMK-NLDHPHIVKLIGIIE----EEPTWIIMELYPYGELGHYLERNKNSLK 522
++ + +E + + L H ++V ++G E+ W+ ME L L ++ +
Sbjct: 55 RQSYSNELLAFRCGLRHVNVVSILGATSLHRFEDGAWLAMEYVGPLNLQTILNDHQQDID 234
Query: 523 VLTLVLYSLQICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSRYI-------- 574
+ +LQ+ + + YL SIN VH D+ N L+ +++ DFG +
Sbjct: 235 SSMRLSLALQMARGLHYLHSINIVHLDLKPANCLLTRDLKLRIADFGCCHQLTPTGLDMG 414
Query: 575 EDEDYYKASVTRL-------------PIKWMSPESINFRRFTTASDVWMFAVCMWEILSF 621
E E + L + + +PE + + + SDV+ + +W++ +
Sbjct: 415 EREGGMAGNELELTPVQGAWKNELAGTLAYRAPELLKGLQPSVRSDVYSLGITLWQMCTR 594
Query: 622 GKQPFFWLENKDVIGVLEKGDRLPKPDLCPP----------VLYTLMTRCWDYDPSDRPR 671
+ P+ + V+ + D P CPP + L T+CW DRP
Sbjct: 595 -QGPYEGVPAHAVVYQVVSKDLRP----CPPPSTEDDPFEVMFRDLYTQCWARRVEDRPT 759
Query: 672 FTELVCSLS 680
++V ++
Sbjct: 760 SLDVVHAIG 786
>01756
Length = 1858
Score = 48.1 bits (113), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 57/233 (24%), Positives = 93/233 (39%), Gaps = 22/233 (9%)
Frame = -3
Query: 461 KDCTLDN-KEKF----MSEAVIMKNLDHPHIVKLIGIIEEEPTWIIMELYPYGELGHYLE 515
K +DN KE F + E I++ L+H ++V LI I + T + + + E
Sbjct: 1649 KKVLMDNEKEGFPITALREIKILQLLNHENVVDLIEICSTKATSANRYKSMFYLVFEFCE 1470
Query: 516 RNKNSLKVLTLVLYSL--------QICKAMAYLESINCVHRDIAVRNILVASPECVKLGD 567
+ L V+++L Q+ + Y+ +HRD+ NIL+ +KL D
Sbjct: 1469 HDLAGLLSNMSVVFNLPEIKEVMKQLMNGLYYIHRNKILHRDMKAANILITKQGVLKLAD 1290
Query: 568 FGLSRY----IEDEDYYKASVTRLPIKWMSPESINF--RRFTTASDVWMFAVCMWEILSF 621
FGL+R + + Y V L W P + R ++TA D W M E+
Sbjct: 1289 FGLARAFSVNLRQPNRYTNRVVTL---WYRPPELLLGDRNYSTAIDQWGAGCIMAEM--- 1128
Query: 622 GKQPFFWLENKDVIGVLEKGDRLPKPDLC---PPVLYTLMTRCWDYDPSDRPR 671
W N + G E+ LC P ++ + R Y+ D P+
Sbjct: 1127 ------WTRNPIMQGTTEQNQLTLITQLCGSITPEVWPGVERLELYNSLDLPQ 987
>12672
Length = 773
Score = 46.2 bits (108), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 38/158 (24%), Positives = 64/158 (40%), Gaps = 16/158 (10%)
Frame = +3
Query: 534 CKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGL---SRYIEDEDYYKASVTRLPIK 590
+ YL VHRDI NIL+ S K+GDF + E + ASV
Sbjct: 21 ASGIQYLNDNGHVHRDIKTANILLDSEYTAKVGDFATVVSAPSGEGKTVQNASVVIGTAA 200
Query: 591 WMSPESINFRRFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPK---- 646
+++PE+I+F +T D + F V + E+++ + E + + + + P+
Sbjct: 201 YLAPEAIHF-DVSTKLDSYSFGVVLLEVITGLVAQDYSREERTLSSHIMENVEEPEEIHD 377
Query: 647 ---------PDLCPPVLYTLMTRCWDYDPSDRPRFTEL 675
PD LY + RC + RP ++
Sbjct: 378 FVDQSAGTWPDGAVDKLYDISMRCLNLSKKQRPNVKDI 491
>32264
Length = 287
Score = 45.1 bits (105), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 21/45 (46%), Positives = 26/45 (57%)
Frame = +1
Query: 638 LEKGDRLPKPDLCPPVLYTLMTRCWDYDPSDRPRFTELVCSLSDV 682
+E G RL + P +Y LM RCW+Y P RP F EL SL D+
Sbjct: 1 IEDGYRLQQNPQTPDSVYKLMLRCWEYVPEKRPHFKELYTSLKDI 135
>26711
Length = 405
Score = 45.1 bits (105), Expect = 1e-04, Method: Composition-based stats.
Identities = 30/99 (30%), Positives = 52/99 (52%), Gaps = 4/99 (4%)
Frame = -2
Query: 532 QICKAMAYLESINCVHRDIAVRNILVASP--ECVKLGDFGLSR--YIEDEDYYKASVTRL 587
Q+ + ++ + VH D+ N+L++ + V+L DFGL+R Y E +
Sbjct: 392 QVLDILQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARKLYPPQETFLNHGTP-- 219
Query: 588 PIKWMSPESINFRRFTTASDVWMFAVCMWEILSFGKQPF 626
+ SPE+++ + +TASDVW V + +LS G+ PF
Sbjct: 218 --GFTSPEALDVKPISTASDVWGVGVLAYILLS-GQSPF 111
>01060
Length = 1800
Score = 44.3 bits (103), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 41/163 (25%), Positives = 76/163 (46%), Gaps = 7/163 (4%)
Frame = +1
Query: 472 MSEAVIMKNLDHPHIVKLIGII-EEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVL-- 528
+ E +++ L H +IV L +I E+E +++ E +L Y+++ + VL L
Sbjct: 214 IREIAMLRELRHTNIVCLEDVIMEDERLFLVFEFLSM-DLKMYIDKFPEGV-VLDRRLVK 387
Query: 529 -YSLQICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSRYIE--DEDYYKASVT 585
Y QI + + VHRD+ +N+L+ +K+ DFG++R Y VT
Sbjct: 388 SYVFQIVTGIXFCHQRRIVHRDLKPQNLLINHTGAIKIADFGMARTFALPVRAYTHEVVT 567
Query: 586 RLPIKWMSPESI-NFRRFTTASDVWMFAVCMWEILSFGKQPFF 627
+ + +PE + +++T DVW ++L + P F
Sbjct: 568 ---LWYRAPEILMGASKYSTPVDVWSIGTIFADMLI--RTPIF 681
>04591
Length = 1117
Score = 44.3 bits (103), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 27/92 (29%), Positives = 42/92 (45%), Gaps = 3/92 (3%)
Frame = -2
Query: 532 QICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSR-YIEDEDYYKASVTRLPIK 590
Q+ + Y+ + +HRDI NIL+ +KL DFGLSR +++ K R+
Sbjct: 873 QLLNGLFYIHTKQILHRDIKAANILLTRDGVLKLADFGLSRPWVKS----KRLTNRVVTL 706
Query: 591 WMSPESINF--RRFTTASDVWMFAVCMWEILS 620
W P + R + D+W M E+ S
Sbjct: 705 WYRPPELLLGEREYGPEIDMWGVGCIMAEMWS 610
>03240
Length = 1683
Score = 43.1 bits (100), Expect = 5e-04, Method: Compositional matrix adjust.
Identities = 38/140 (27%), Positives = 66/140 (47%), Gaps = 9/140 (6%)
Frame = -3
Query: 455 AVKTCKKDCTLDNKE--KFMSEAVIMKNLDHPHIVKLIGIIEEEP-TWIIMELYPYGELG 511
A+KT +K L + +E I+ D+ +VKL ++ + +M+ P G+L
Sbjct: 1204 AMKTLRKSDVLKRNQVAHVKAERDILAEADNEWVVKLYYSFQDHNYLYFVMDYVPGGDLM 1025
Query: 512 HYLERNKNSLKVLTLVL---YSLQICKAMAYLESINCVHRDIAVRNILVASPECVKLGDF 568
L R +++L L Y ++ +A+ + + +HRDI NIL+ +KL DF
Sbjct: 1024 GLLIR----MEILDEPLARFYVAELVQAIESVHRMGFIHRDIKPDNILIDRNGHIKLTDF 857
Query: 569 GLS---RYIEDEDYYKASVT 585
GL R+ + YY+ T
Sbjct: 856 GLCTGFRWTHNSKYYQRDGT 797
>04138
Length = 800
Score = 41.6 bits (96), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 45/177 (25%), Positives = 71/177 (40%), Gaps = 7/177 (3%)
Frame = +1
Query: 537 MAYLESINCVHRDIAVRNILVASPECVKLGDFGLSRY----IEDEDYYKASVTRLPIKWM 592
+ Y+ +HRD+ NIL+ +KL DFGL+R + + Y V L W
Sbjct: 52 LYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTL---WY 222
Query: 593 SPESINF--RRFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLC 650
P + R ++TA D W M E+ W N + G E+
Sbjct: 223 RPPELLLGDRNYSTAIDQWGAGCIMAEM---------WTRNPIMQGTTEQNQ-------- 351
Query: 651 PPVLYTLMTR-CWDYDPSDRPRFTELVCSLSDVYQMEKDIAMEQERNARYRTPKILE 706
TL+T+ C P P T+ LS +Q++ +A ++ R R +IL+
Sbjct: 352 ----LTLITQLCGSITPEVWPGVTQ----LSMYHQIKGALAAGRKNIIRDRFARILK 498
>35671
Length = 567
Score = 41.6 bits (96), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 18/50 (36%), Positives = 29/50 (58%)
Frame = -3
Query: 639 EKGDRLPKPDLCPPVLYTLMTRCWDYDPSDRPRFTELVCSLSDVYQMEKD 688
+KG+RL KP C Y +M +CW +RP F +LV + ++Y+ +D
Sbjct: 565 QKGNRLAKPISCTDEAYKVMLQCWTESREERPTFKKLVPVMENLYRSHRD 416
>01966
Length = 1735
Score = 41.2 bits (95), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 38/159 (23%), Positives = 73/159 (45%), Gaps = 9/159 (5%)
Frame = -1
Query: 447 HKGEKINVAVKTCKKDCTLDN-KEKFMSEAVIMKNLDHPHIVKLIGII-EEEPTWIIMEL 504
H+ +A+K + + D + E +++ L H +IV L +I E+E +++ E
Sbjct: 1648 HRATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTNIVCLEDVIMEDERLFLVFEF 1469
Query: 505 YPYGELGHYLERNKNSLKVLTLVL--YSLQICKAMAYLESINCVHRDIAVRNILVASPEC 562
+L Y+++ + + ++ Y QI + + VHRD+ +N+L+
Sbjct: 1468 LSM-DLKMYIDKFPEGVVLDRRLVKSYVFQIVTGINFCHQRRIVHRDLKPQNLLINHTGA 1292
Query: 563 VKLGDFGLSRY--IEDEDYYKASVT---RLPIKWMSPES 596
+K+ DFG++R + Y VT R P M P+S
Sbjct: 1291 IKIADFGMARTFALPVRAYTHEVVTLWYRAPEILMGPQS 1175
>07933
Length = 728
Score = 39.3 bits (90), Expect = 0.008, Method: Compositional matrix adjust.
Identities = 14/29 (48%), Positives = 20/29 (68%)
Frame = +3
Query: 647 PDLCPPVLYTLMTRCWDYDPSDRPRFTEL 675
P+ CP +LY +M +CW +PS RP F +L
Sbjct: 3 PNYCPNLLYNIMMQCWSAEPSARPTFHKL 89
>07836
Length = 1478
Score = 38.1 bits (87), Expect = 0.018, Method: Compositional matrix adjust.
Identities = 47/162 (29%), Positives = 73/162 (45%), Gaps = 24/162 (14%)
Frame = -1
Query: 481 LDHPHIVKLIGI-IEEEPTW----IIMELYPYGELGHYL-ERNKNSLKVLTLVLYSLQIC 534
L H +I+ I I+ +W +I + + G L YL R +S ++L L +S
Sbjct: 1394 LRHENILGFIAADIKGTGSWTQLFLITDYHENGSLHDYLLSRVLDSSEMLALA-HSAICG 1218
Query: 535 KAMAYLESINC------VHRDIAVRNILVASPECVKLGDFGLS-RYIEDEDYYKASVTRL 587
A ++E HRDI +NILV + D GL+ RYI + + + V
Sbjct: 1217 LAHLHIEIFGTRGKPAIAHRDIKSKNILVKKNGTCCIADLGLAVRYISESN--EVDVAPN 1044
Query: 588 P----IKWMSPESI-------NFRRFTTASDVWMFAVCMWEI 618
P ++M+PE + NF F A D++ F + MWEI
Sbjct: 1043 PRQGTKRYMAPEVLEMLLNVKNFDAFKQA-DMYAFGLVMWEI 921
>28157
Length = 400
Score = 37.4 bits (85), Expect = 0.035, Method: Compositional matrix adjust.
Identities = 34/127 (26%), Positives = 59/127 (46%), Gaps = 8/127 (6%)
Frame = +3
Query: 453 NVAVKTCKKDCTLDNKEKFMSEAVIMKNLDHPHIVKLIGIIEEEPTWIIMELYPYGELGH 512
+VAVK + + K+ FM E + + HP+IV L G + P ++ME G L +
Sbjct: 6 DVAVKRIESE---QEKKSFMQELKQLSRVSHPNIVCLYGACRDHPVCLVMEYAEGGSLYN 176
Query: 513 YLERN--KNSLKVLTLVLYSLQICKAMAYLESIN---CVHRDIAVRNILVASPEC---VK 564
L + + + + LQ + YL + +HRD+ N+L+ +C +K
Sbjct: 177 VLHGSGPQPQYTAAHAMNWLLQCALGVEYLHGMKPKALIHRDLKPPNLLLI--QCGTKLK 350
Query: 565 LGDFGLS 571
+ DFG +
Sbjct: 351 ICDFGTA 371
>32359
Length = 928
Score = 36.6 bits (83), Expect = 0.050, Method: Compositional matrix adjust.
Identities = 30/103 (29%), Positives = 51/103 (49%), Gaps = 10/103 (9%)
Frame = -1
Query: 454 VAVKTCKKDCTLDNKEKFMSEAVIMKNLDHPHIVKLIGII-------EEEPTWIIMELYP 506
VA+K +D N+E IM+ L+H +IVKL +E +++E P
Sbjct: 346 VAIKKVLQDKRFKNRE-----LQIMRKLEHQNIVKLKFFFYSSGEKKDEVFLNLVLEYVP 182
Query: 507 ---YGELGHYLERNKNSLKVLTLVLYSLQICKAMAYLESINCV 546
Y HY ++K ++ +L + LY Q+ +++AY+ S CV
Sbjct: 181 ETVYRVARHY-SKSKQTIPILYIKLYMYQLFRSLAYIHSQACV 56
>15741
Length = 402
Score = 35.0 bits (79), Expect = 0.14, Method: Composition-based stats.
Identities = 14/44 (31%), Positives = 24/44 (54%)
Frame = -3
Query: 513 YLERNKNSLKVLTLVLYSLQICKAMAYLESINCVHRDIAVRNIL 556
+L N L ++L + + MA++ + VHRD+A RN+L
Sbjct: 133 FLTSTANDLTARDFFSFALHVARGMAHVANNKIVHRDVAARNVL 2
>01392
Length = 1806
Score = 34.7 bits (78), Expect = 0.19, Method: Compositional matrix adjust.
Identities = 34/129 (26%), Positives = 55/129 (42%), Gaps = 12/129 (9%)
Frame = -1
Query: 511 GHYLERNKNSLKVLTLVLYSLQICKAMAYLESINCVHRDIAVRNILVASPE---CVKLGD 567
GH ER + L I +A+ +L S HRD+ NIL + VK+ D
Sbjct: 1806 GHLCEREAS--------LVVRHIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICD 1651
Query: 568 FGLSRYIE-DEDYYKASVTRLPI---KWMSPESINFR-----RFTTASDVWMFAVCMWEI 618
F L+ I D D K P+ ++M+PE ++ + D+W + ++ I
Sbjct: 1650 FDLASGISCDGDGTKTPELLTPVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILY-I 1474
Query: 619 LSFGKQPFF 627
+ G PF+
Sbjct: 1473 MLCGYPPFY 1447
>38046
Length = 446
Score = 33.9 bits (76), Expect = 0.39, Method: Composition-based stats.
Identities = 16/32 (50%), Positives = 20/32 (62%)
Frame = -1
Query: 533 ICKAMAYLESINCVHRDIAVRNILVASPECVK 564
I AMAY+E N +HR++ RNILV VK
Sbjct: 98 IADAMAYMEKENFIHRNLGDRNILVGPNNRVK 3
>27287
Length = 514
Score = 33.5 bits (75), Expect = 0.44, Method: Compositional matrix adjust.
Identities = 14/34 (41%), Positives = 19/34 (55%)
Frame = -2
Query: 646 KPDLCPPVLYTLMTRCWDYDPSDRPRFTELVCSL 679
KP ++ +M CW DP+DRP F+ LV L
Sbjct: 507 KPPYASSEMFGIMHSCWQEDPNDRPSFSRLVQEL 406
>21433
Length = 590
Score = 31.6 bits (70), Expect = 1.5, Method: Composition-based stats.
Identities = 23/91 (25%), Positives = 38/91 (41%)
Frame = +2
Query: 529 YSLQICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVTRLP 588
Y Q+ A+ Y +HRDI N+L+ +K+ DFG S + T
Sbjct: 182 YIYQLSSALEYCHYRKVIHRDIKPENLLLGLKGDLKIADFGWSVHAPSSRRTTMCGT--- 352
Query: 589 IKWMSPESINFRRFTTASDVWMFAVCMWEIL 619
+ ++ PE + + D+W V +E L
Sbjct: 353 LDYLPPEMVEGKTHDENVDLWSLGVLCYEFL 445
>26560
Length = 398
Score = 31.6 bits (70), Expect = 1.7, Method: Composition-based stats.
Identities = 24/99 (24%), Positives = 44/99 (44%)
Frame = -1
Query: 528 LYSLQICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVTRL 587
Y+ ++ + ++ S V+RD+ NIL+ V++ D GL+ + + + T
Sbjct: 344 FYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGLACDFSKKRPHASVGTH- 168
Query: 588 PIKWMSPESINFRRFTTASDVWMFAVCMWEILSFGKQPF 626
+M+PE + + +S W CM L G PF
Sbjct: 167 --GYMAPEVLMKGQSYDSSADWFSFGCMLYKLLKGHSPF 57
>16708
Length = 1397
Score = 31.2 bits (69), Expect = 2.2, Method: Compositional matrix adjust.
Identities = 28/112 (25%), Positives = 46/112 (41%), Gaps = 7/112 (6%)
Frame = -1
Query: 500 IIMELYPYGELGHYLERNKN-------SLKVLTLVLYSLQICKAMAYLESINCVHRDIAV 552
I++ Y G L + KN S + + +C A+ ++ + VH D+
Sbjct: 1184 ILLHFYEMGPLCNVYAHYKNKEMPIRWSNPAMVCCIAGQXVC-ALEHIHELGVVHMDVKA 1008
Query: 553 RNILVASPECVKLGDFGLSRYIEDEDYYKASVTRLPIKWMSPESINFRRFTT 604
N+LV + KL D+G+++ YK V P + S N R F T
Sbjct: 1007 DNVLVDAHGNCKLTDYGIAQ------LYK--VYPAPTETHSSGCTNKRTFYT 876
>37602
Length = 804
Score = 30.0 bits (66), Expect = 4.8, Method: Compositional matrix adjust.
Identities = 15/34 (44%), Positives = 18/34 (52%)
Frame = -1
Query: 535 KAMAYLESINCVHRDIAVRNILVASPECVKLGDF 568
K + YL +HRDI NIL+ VKL DF
Sbjct: 186 KGLHYLHRRGKMHRDIKGANILLTEEGDVKLADF 85
>00302
Length = 927
Score = 30.0 bits (66), Expect = 5.4, Method: Composition-based stats.
Identities = 14/42 (33%), Positives = 24/42 (57%)
Frame = -2
Query: 537 MAYLESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDED 578
+ YL+S+ C+H+ + LVA+ VK F ++R + ED
Sbjct: 458 LVYLDSV-CIHKSVVYEKCLVATDISVKYRLFTIARLVAPED 336
>26009
Length = 886
Score = 29.3 bits (64), Expect = 7.7, Method: Compositional matrix adjust.
Identities = 11/30 (36%), Positives = 19/30 (63%)
Frame = +3
Query: 532 QICKAMAYLESINCVHRDIAVRNILVASPE 561
Q+ A+ ++ S VHRDI N+L+ +P+
Sbjct: 735 QLVSALDFMHSKQLVHRDIKPENVLILTPD 824
>02638
Length = 1490
Score = 29.3 bits (64), Expect = 8.6, Method: Compositional matrix adjust.
Identities = 24/92 (26%), Positives = 42/92 (45%), Gaps = 4/92 (4%)
Frame = +1
Query: 589 IKWMSPESINFRRFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEK----GDRL 644
I +M+PE + + A DVW M E+ + + P+ + + + ++ K D
Sbjct: 28 IAFMAPEVLRGESYGRACDVWSVGCVMIEMCTC-RPPWNSHDISNHLALIFKIASSVDPP 204
Query: 645 PKPDLCPPVLYTLMTRCWDYDPSDRPRFTELV 676
P P+ P + LM RC + D RP +L+
Sbjct: 205 PIPENMSPPVRDLMLRCLEQDSDFRPSAKDLL 300
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000366483 | hsapiens_gene_ensembl |
Ubiquitin-activating enzyme E1 (A1S9 protein).
[Source:Uniprot/SWISSPROT;Acc:P22314]
(284 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
21876 200 5e-52
21008 117 6e-27
06604 117 7e-27
19711 75 2e-14
20367 75 4e-14
00369 51 4e-07
18902 28 3.9
15198 28 5.2
>21876
Length = 894
Score = 200 bits (509), Expect = 5e-52, Method: Compositional matrix adjust.
Identities = 113/236 (47%), Positives = 149/236 (63%), Gaps = 9/236 (3%)
Frame = -1
Query: 58 NGSEADIDEGLYSRQLYVLGHEAMKR---LQTSSVLVSGLRGLGVEIAKNIILGGVKAVT 114
NG+ DIDEGL GHEAM++ LQ S + G GLG+EIAKN++LGGVK+V+
Sbjct: 894 NGAADDIDEGLVXSPAVCAGHEAMRKMAKLQCSDLWAMG--GLGIEIAKNVVLGGVKSVS 721
Query: 115 LHDQGTAQWADLSSQFYLREEDIGKNRAEVSQPRLAELNSYVPVTAYTGPLVEDFLSGFQ 174
+HD G + DLSSQF+LR+ED+GKNRAEVSQPRLAELNSYVP+++ TG DF G
Sbjct: 720 IHDPGKVVFGDLSSQFFLRDEDVGKNRAEVSQPRLAELNSYVPISSSTG----DFG*GLL 553
Query: 175 VVVLTNTPLEDQLRV------GEFCHNRGIKLVVADTRGLFGQLFCDFGEEMILTDSNGE 228
V V + DQL V G ++ + DFG ++TD +GE
Sbjct: 552 VQVSGGS--TDQLFVR*TDPCGRVLSLSQHQVHCGRNAWTVWENLLDFGSNFVITDGDGE 379
Query: 229 QPLSAMVSMVTKDNPGVVTCLDEARHGFESGDFVSFSEVQGMVELNGNQPMEIKVL 284
QP+S M++ + K + VV +DE +HG E GD+V+F EVQGM ELNG +P++IKVL
Sbjct: 378 QPISCMIADIEKGDNSVVATVDETKHGLEDGDYVTFKEVQGMTELNGCKPVKIKVL 211
>21008
Length = 408
Score = 117 bits (293), Expect = 6e-27, Method: Compositional matrix adjust.
Identities = 63/128 (49%), Positives = 84/128 (65%), Gaps = 2/128 (1%)
Frame = +3
Query: 33 PGSNCSPAQSVLSEVPSVPTNGMAKNGSEADIDEGLYSRQLYVLGHEAMKRLQTSSVLVS 92
PG NC ++ T MA S+ +ID+ LYSRQ YVLG AMKR+ SSVL+
Sbjct: 54 PGFNCF-------KINLCNTETMA---SDMEIDDSLYSRQRYVLGDSAMKRMAQSSVLIH 203
Query: 93 GLRGLGVEIAKNIILGGVKAVTLHDQGTAQWADLSSQFYLREEDI--GKNRAEVSQPRLA 150
GL GLG+EIAKNI+L GVK++T+ D T+ +DL +QF++R+ D+ KNRAE +LA
Sbjct: 204 GLGGLGIEIAKNIVLAGVKSLTVQDSKTSCTSDLGTQFFVRQADVDAAKNRAEACAGKLA 383
Query: 151 ELNSYVPV 158
ELN YV +
Sbjct: 384 ELNPYVKI 407
>06604
Length = 1748
Score = 117 bits (292), Expect = 7e-27, Method: Compositional matrix adjust.
Identities = 62/154 (40%), Positives = 89/154 (57%), Gaps = 3/154 (1%)
Frame = -2
Query: 67 GLYSRQLYVLGHEAMKRLQTSSVLVSGLRGLGVEIAKNIILGGVKAVTLHDQGTAQWADL 126
LY RQ+ + G +A +RL+ +SVL+ G+RGLG E+AKNI+L G+K++TL D A D
Sbjct: 1735 ALYDRQIRLWGLDAQRRLRAASVLLVGVRGLGAEVAKNIVLAGIKSLTLLDPSLADEEDT 1556
Query: 127 SSQFYLREEDIGKNRAEVSQPRLAELNSYVPVTAYTGPL---VEDFLSGFQVVVLTNTPL 183
++QF + +IGKNRAE S R LN V VTA T + +DF++ F VV T +
Sbjct: 1555 AAQFLIPRSEIGKNRAEASLERTQLLNPMVTVTADTCSIDDKDDDFVTSFDVVCATGCGV 1376
Query: 184 EDQLRVGEFCHNRGIKLVVADTRGLFGQLFCDFG 217
R+ C + G+ D G +G +F D G
Sbjct: 1375 STLRRLDRVCRDAGVMFYAGDVFGFYGYMFADLG 1274
>19711
Length = 1114
Score = 75.5 bits (184), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 36/71 (50%), Positives = 46/71 (64%)
Frame = +3
Query: 214 CDFGEEMILTDSNGEQPLSAMVSMVTKDNPGVVTCLDEARHGFESGDFVSFSEVQGMVEL 273
CDFG+ + D GE+ ++ +TK NPGVVTCLD HG E+GD V+F EV+GM +L
Sbjct: 3 CDFGDTFEVMDPTGEEAKEVFIANITKANPGVVTCLDNLLHGLETGDLVTFKEVKGMEQL 182
Query: 274 NGNQPMEIKVL 284
N Q IKVL
Sbjct: 183 NSQQ-CAIKVL 212
>20367
Length = 859
Score = 74.7 bits (182), Expect = 4e-14, Method: Compositional matrix adjust.
Identities = 52/165 (31%), Positives = 76/165 (46%), Gaps = 11/165 (6%)
Frame = -1
Query: 69 YSRQLYVLGHEAMKRLQTSSVLVSGLRGLGVEIAKNIILGGVKAVTLHDQGTAQWADLSS 128
Y RQL + G L+T+ V + G EI KN+IL G+ + T+ D Q D+ +
Sbjct: 814 YDRQLRLWGDHGQSALETARVCLINATATGTEILKNVILPGIGSFTIVDGNKVQGEDVGN 635
Query: 129 QFYLREEDIGKNRAEVSQPRLAELNSYVPVTAYTGPLVE-----------DFLSGFQVVV 177
F+L+ + IGK+RA+V+ L ELN V TG VE DF + F +V+
Sbjct: 634 NFFLQVDSIGKSRAQVATELLGELNDDV-----TGNFVEENVENLLESNADFFTTFSIVI 470
Query: 178 LTNTPLEDQLRVGEFCHNRGIKLVVADTRGLFGQLFCDFGEEMIL 222
TN + L++ I L+V G G L E I+
Sbjct: 469 ATNLHEKTLLQLAGVLWENNIPLLVCRCYGFIGYLRLVLKEHTII 335
>00369
Length = 1082
Score = 51.2 bits (121), Expect = 4e-07, Method: Compositional matrix adjust.
Identities = 35/99 (35%), Positives = 53/99 (53%), Gaps = 6/99 (6%)
Frame = +3
Query: 85 QTSSVLVSGLRGLGVEIAKNIILGGVKAVTLHDQGTAQWADLSSQFYLREEDIGKNRAEV 144
+T +LV G GLG E+ K++ L G + + D T ++L+ QF R +D+G +AEV
Sbjct: 213 ETCKLLVIGAGGLGCELLKDLALMGFFDIHVIDMDTIDVSNLNRQFLFRPKDVGSPKAEV 392
Query: 145 SQPRLAELNSYVP---VTAYTGPLV---EDFLSGFQVVV 177
+ A +NS VP VT + + E F GF V+V
Sbjct: 393 AA---AFINSRVPGCKVTPHFAKIQDYDESFYRGFHVIV 500
>18902
Length = 1423
Score = 28.1 bits (61), Expect = 3.9, Method: Compositional matrix adjust.
Identities = 23/72 (31%), Positives = 32/72 (44%), Gaps = 5/72 (6%)
Frame = +1
Query: 94 LRGLGVEIAKNIILGGVKAVTLHDQGTAQWADLSSQFYLR-----EEDIGKNRAEVSQPR 148
L G I I LGG+ AV L+ A W + L+ + +N A ++ PR
Sbjct: 670 LVAFGAAIDLLIDLGGIAAVNLN---AADWVAIVMTDVLKLCCEHQRRR*RNTASLATPR 840
Query: 149 LAELNSYVPVTA 160
LA L P+TA
Sbjct: 841 LAHLKRGQPMTA 876
>15198
Length = 1075
Score = 27.7 bits (60), Expect = 5.2, Method: Compositional matrix adjust.
Identities = 25/101 (24%), Positives = 42/101 (41%)
Frame = +3
Query: 70 SRQLYVLGHEAMKRLQTSSVLVSGLRGLGVEIAKNIILGGVKAVTLHDQGTAQWADLSSQ 129
S +Y+L + R +++ +G N+ILG L QGT+ +SS
Sbjct: 144 SAPIYML-EPSFDRSFFFNLITQSFNNIGESCMTNVILGFTAMDKLAQQGTSGLKQISSA 320
Query: 130 FYLREEDIGKNRAEVSQPRLAELNSYVPVTAYTGPLVEDFL 170
F L + N ++ Q +L N++ + P DFL
Sbjct: 321 FNLCSP-LMDNGSDYRQLQLWIRNAFTFLAMLDYPYPTDFL 440
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000380638 | hsapiens_gene_ensembl | Protein
tyrosine kinase 2 beta (EC 2.7.10.2) (Focal adhesion kinase 2) (FADK
2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK
beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion
focal tyrosine kinase) (RAFTK). [Source:Uniprot/SWISSPROT;Acc:Q14289]
(1009 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
06405 202 5e-52
21808 179 6e-45
09007 166 3e-41
04852 162 8e-40
11780 94 6e-36
07291 127 2e-29
17300 120 3e-29
20640 125 7e-29
07940 117 3e-26
14116 113 4e-25
18996 111 1e-24
22005 90 1e-23
08294 106 4e-23
14477 88 2e-17
13305 86 1e-16
17637 85 2e-16
17253 83 6e-16
12721 77 3e-14
01718 77 4e-14
18921 72 1e-12
19301 69 1e-11
27546 66 9e-11
14420 65 1e-10
13066 60 3e-09
00300 59 7e-09
31885 59 9e-09
07833 58 2e-08
30755 56 8e-08
21079 55 2e-07
29581 54 3e-07
19094 53 5e-07
15910 52 1e-06
19761 52 2e-06
01707 51 3e-06
14126 50 5e-06
18484 50 6e-06
13212 50 6e-06
25550 49 8e-06
00715 49 1e-05
01756 48 2e-05
12672 46 6e-05
32264 45 1e-04
26711 45 1e-04
01060 44 2e-04
04591 44 2e-04
03240 43 5e-04
04138 42 0.001
35671 42 0.002
01966 41 0.002
07933 39 0.008
07836 38 0.018
28157 37 0.035
32359 37 0.050
15741 35 0.14
01392 35 0.19
38046 34 0.39
27287 33 0.44
21433 32 1.5
26560 32 1.7
16708 31 2.2
37602 30 4.8
00302 30 5.4
26009 29 7.7
02638 29 8.6
>06405
Length = 1965
Score = 202 bits (514), Expect = 5e-52, Method: Compositional matrix adjust.
Identities = 100/254 (39%), Positives = 153/254 (60%), Gaps = 5/254 (1%)
Frame = +1
Query: 454 VAVKTCKKDCTLDNKEKFMSEAVIMKNLDHPHIVKLIGIIEEEPT-WIIMELYPYGELGH 512
VAVKT K+D N F+ EA IMK + HP++V+L+G+ EP +I+ E P+G L
Sbjct: 343 VAVKTLKEDTMALND--FLEEAAIMKEMKHPNLVQLLGVCTREPPFYIVTEFMPHGNLLD 516
Query: 513 YLERNKNSLKVLTLVLY-SLQICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLS 571
YL + T ++Y + QI MAYLE+ N +HRD+A RN LVA VK+ DFGL+
Sbjct: 517 YLRSSTREENGPTALMYMATQIASGMAYLETKNFIHRDLAARNCLVADSNMVKVADFGLA 696
Query: 572 RYIEDEDYYKASVTRLPIKWMSPESINFRRFTTASDVWMFAVCMWEILSFGKQPFFWLEN 631
R ++D+ Y + PIKW +PE + F RF+T SD+W F V +WE+ ++G P+ +E
Sbjct: 697 RLMKDDTYTAHIGAKFPIKWTAPEGLAFNRFSTRSDIWAFGVLLWELATYGMSPYPGVEL 876
Query: 632 KDVIGVLEKGDRLPKPDLCPPVLYTLMTRCWDYDPSDRPRFTELVCSLSDVYQME---KD 688
+V +LE+G R+ +P P +Y LM +CW +DP DRP F E+ L ++++ ++
Sbjct: 877 TEVYHLLERGYRMERPPGTPADVYILMLKCWQWDPKDRPTFKEIHFLLENMFEKSSICEE 1056
Query: 689 IAMEQERNARYRTP 702
+ E E+N + + P
Sbjct: 1057VEKELEKNDKKQMP 1098
>21808
Length = 1011
Score = 179 bits (454), Expect = 6e-45, Method: Compositional matrix adjust.
Identities = 91/220 (41%), Positives = 135/220 (61%), Gaps = 1/220 (0%)
Frame = +1
Query: 454 VAVKTCKKDCTLDNKEKFMSEAVIMKNLDHPHIVKLIGI-IEEEPTWIIMELYPYGELGH 512
VA+KT K T+D K+ F++EA IMK L HP +++L + +++P +II EL G L
Sbjct: 28 VAIKTLKSG-TMDPKD-FLAEAQIMKKLRHPKLIQLYAVCTQDDPIFIITELMKNGSLLE 201
Query: 513 YLERNKNSLKVLTLVLYSLQICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSR 572
+L+ LK+ L+ QI MAYLES N +HRD+A RNILV+ VK+ DFGL+R
Sbjct: 202 FLQGKGRVLKLPALIDIGAQIACGMAYLESQNYIHRDLAARNILVSDNNTVKIADFGLAR 381
Query: 573 YIEDEDYYKASVTRLPIKWMSPESINFRRFTTASDVWMFAVCMWEILSFGKQPFFWLENK 632
I++++Y R PIKW +PE+ N+ RFT SDVW F + + E +++G+ P+ + N
Sbjct: 382 VIKEDEYEARVGARFPIKWTAPEAANYNRFTIKSDVWSFGILLTETVTYGRVPYPGMTNA 561
Query: 633 DVIGVLEKGDRLPKPDLCPPVLYTLMTRCWDYDPSDRPRF 672
+V+ +E G R+P P CP LY +M CW + +RP
Sbjct: 562 EVLHQVEHGYRMPCPPGCPKPLYDIMLECWRKEEMERPHL 681
>09007
Length = 1440
Score = 166 bits (421), Expect = 3e-41, Method: Compositional matrix adjust.
Identities = 99/307 (32%), Positives = 163/307 (53%), Gaps = 10/307 (3%)
Frame = -1
Query: 406 PDETLRRPGGPQYGIAREDVVLNRILXXXXXXXXXXXXXTNHKGEKINVAVKTCKKDCTL 465
P + RP + I+++ V L++ L T GEK+ VAVK KD
Sbjct: 930 PVSAVVRPARGKQLISKDCVALSKSLGQGHFGTVRQAIWTAESGEKVQVAVKCLSKDKIH 751
Query: 466 DNKEKFMSEAVIMKNLDHPHIVKLIGIIEEEPTWIIM--ELYPYGELGHYLER--NKNSL 521
+ ++F+ E IM+ LDH +IV++ G++ + I++ EL P L ++ +
Sbjct: 750 KDGQEFLKETAIMQMLDHENIVRVYGVVMDNGADIMLVTELAPMRSLLECVKEVSARVDF 571
Query: 522 KVLTLVLYSLQICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSRYI-EDEDYY 580
V L +S Q+C M+YLES VHRD+A RNIL+ S VK+ D G+S + ++YY
Sbjct: 570 SVPRLCDFSQQVCDGMSYLESKRLVHRDLAARNILLFSKSKVKISDVGVSGALGAGKEYY 391
Query: 581 KASVT---RLPIKWMSPESINFRRFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGV 637
++ T + + W +PES F++ASDVW F V +WE + G QP+ L + ++
Sbjct: 390 QSQQTIHLQNAVAWCAPESFRNLCFSSASDVWAFGVLLWEFFTHGFQPWAGLNGQQIMEA 211
Query: 638 LE--KGDRLPKPDLCPPVLYTLMTRCWDYDPSDRPRFTELVCSLSDVYQMEKDIAMEQER 695
++ + RL +PDLCP Y +M +CW+ +P RP F++L +L + + I ++ +
Sbjct: 210 VDAPQSQRLEQPDLCPKEYYAVMLKCWEQEPQRRPTFSQLFLTLPQI----RPIQVKAVK 43
Query: 696 NARYRTP 702
+A TP
Sbjct: 42 DAPSSTP 22
>04852
Length = 1462
Score = 162 bits (409), Expect = 8e-40, Method: Compositional matrix adjust.
Identities = 92/255 (36%), Positives = 135/255 (52%), Gaps = 31/255 (12%)
Frame = +1
Query: 453 NVAVKTCKKDCTLDNKEKFMSEAVIMKNL----DHPHIVKLIGI-IEEEPTWIIMELYPY 507
VAVK + T ++ F+ E +MK + H +IV +G + P W+I+E
Sbjct: 25 TVAVKMLRDIVTAVEEQDFVQELQVMKAVKKMGSHINIVNFLGCCTQGGPLWVIVEFAKN 204
Query: 508 GELGHYLERNKNSLKVL------------------------TLVLYSLQICKAMAYLESI 543
G L +LE ++ + L+ Y+ QI + M +L S
Sbjct: 205 GNLRDFLESCRDGINGYGKFVSPQDPGWYTKTPGGHVIRRKNLLSYAFQIARGMEFLASR 384
Query: 544 NCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKA-SVTRLPIKWMSPESINFRRF 602
C+HRD+A RN+LV +K+ DFGLSR DYYK S RLP+KWM+PE++ R+
Sbjct: 385 KCIHRDLAARNVLVTEEHVLKIADFGLSR---TGDYYKKRSGGRLPVKWMAPEALFDMRY 555
Query: 603 TTASDVWMFAVCMWEILSFGKQPFFWLENKDVIG-VLEKGDRLPKPDLCPPVLYTLMTRC 661
TT SDVW F V +WEI S G P+ + N+++ +L+ R+P+P+L LY +M RC
Sbjct: 556 TTKSDVWSFGVVLWEIFSLGGMPYASIPNEELYSKLLDDAYRMPRPELASGNLYAIMERC 735
Query: 662 WDYDPSDRPRFTELV 676
W PSDRP F++LV
Sbjct: 736 WLNRPSDRPEFSQLV 780
>11780
Length = 1713
Score = 94.0 bits (232), Expect(2) = 6e-36, Method: Compositional matrix adjust.
Identities = 53/146 (36%), Positives = 85/146 (58%), Gaps = 2/146 (1%)
Frame = +3
Query: 454 VAVKTCK-KDCTLDNKEKFMSEAVIMKNLDHPHIVKLIGIIEEEPTWIIMELYPYGELGH 512
VA+K K KD ++ F+ EA +M +L H ++V+LIG++ E +++ E G L
Sbjct: 675 VAIKQLKDKD---RGEQSFLQEASVMTSLRHDNLVRLIGVVLGETIFLVTEFMGKGNLVE 845
Query: 513 YL-ERNKNSLKVLTLVLYSLQICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLS 571
YL R ++ + + ++ C AM YLES VHRD+A RN+LV K+ DFGL+
Sbjct: 846 YLRSRGRSVITKKDQINFATDTCAAMEYLESKRLVHRDLAARNVLVHDDGKAKVSDFGLA 1025
Query: 572 RYIEDEDYYKASVTRLPIKWMSPESI 597
++ D+ + SV + PIKW +PE++
Sbjct: 1026KF---GDFSQTSV-KFPIKWTAPEAL 1091
Score = 76.6 bits (187), Expect(2) = 6e-36, Method: Compositional matrix adjust.
Identities = 31/81 (38%), Positives = 55/81 (67%)
Frame = +1
Query: 601 RFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTR 660
+FT+ SD+W F + +WEI SFG+ P+ + DV+ +E+G R+ P+ CPP +Y++M +
Sbjct: 1102 KFTSKSDMWSFGILLWEIYSFGRVPYPRIPLTDVVMHVERGYRMEAPEGCPPEIYSIMKQ 1281
Query: 661 CWDYDPSDRPRFTELVCSLSD 681
W+ DP++RP F ++ L++
Sbjct: 1282 AWELDPNERPTFKSVLARLNN 1344
>07291
Length = 833
Score = 127 bits (319), Expect = 2e-29, Method: Compositional matrix adjust.
Identities = 61/157 (38%), Positives = 95/157 (60%), Gaps = 2/157 (1%)
Frame = +1
Query: 521 LKVLTLVLYSLQICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYY 580
L V+ L+ + QI MAYL+ + VHR++A RN +V ++L D+G++ + + YY
Sbjct: 40 LTVVQLLDFGRQIADGMAYLQEVKVVHRNLAARNCIVTEDGRLQLSDYGVTGSLFPQSYY 219
Query: 581 KA--SVTRLPIKWMSPESINFRRFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVL 638
A S R +KWM+PE+I+ F++ SDVW F V +WE+L+ G P+ +EN ++ L
Sbjct: 220 TADDSPARDLVKWMAPETIDNFHFSSKSDVWAFGVVLWELLTRGITPYPDVENSSLLPYL 399
Query: 639 EKGDRLPKPDLCPPVLYTLMTRCWDYDPSDRPRFTEL 675
++G R+ KP P +Y +MT CW+ P RP F EL
Sbjct: 400 KEGHRMKKPKQSPEPVYEMMTACWNESPEQRPDFAEL 510
>17300
Length = 480
Score = 120 bits (302), Expect(2) = 3e-29, Method: Composition-based stats.
Identities = 55/116 (47%), Positives = 76/116 (65%), Gaps = 3/116 (2%)
Frame = +1
Query: 533 ICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSRYIED---EDYYKASVTRLPI 589
I M L + VHRD+A RNILV K+ DFGLSR IE E Y ++P+
Sbjct: 1 ISSGMGXLADMGYVHRDLAARNILVNEILVCKVADFGLSREIESDTTEGAYTTKGGKIPV 180
Query: 590 KWMSPESINFRRFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLP 645
+W +PE+I +R+FT+ASDVW F V MWE++S+G++P++ N+DVI +EKG RLP
Sbjct: 181 RWTAPEAIAYRKFTSASDVWSFGVVMWEVMSYGERPYWNWSNQDVIKAVEKGYRLP 348
Score = 26.9 bits (58), Expect(2) = 3e-29, Method: Compositional matrix adjust.
Identities = 11/35 (31%), Positives = 19/35 (54%)
Frame = +2
Query: 650 CPPVLYTLMTRCWDYDPSDRPRFTELVCSLSDVYQ 684
CP L+ LM W + S RP+ + +V +L + +
Sbjct: 359 CPEALHQLMLDAWQKERSHRPKMSMVVKTLDKLIR 463
>20640
Length = 1492
Score = 125 bits (315), Expect = 7e-29, Method: Compositional matrix adjust.
Identities = 58/140 (41%), Positives = 88/140 (62%), Gaps = 1/140 (0%)
Frame = +1
Query: 546 VHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKAS-VTRLPIKWMSPESINFRRFTT 604
VHRD+A RN LV VK+ DFGL+R + DYY+ S +PI+WM E+I + +F+T
Sbjct: 10 VHRDLATRNCLVGHDLVVKISDFGLARSVHSVDYYRGSEHDAIPIRWMPLEAILYNKFST 189
Query: 605 ASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTRCWDY 664
SDVW F V +WEI +F QP++ L +++V+ +++G L P+ PP +Y LM +CW
Sbjct: 190 QSDVWSFGVVLWEIFAFALQPYYGLTHEEVVRFVKEGKVLACPERTPPPMYELMKQCWHR 369
Query: 665 DPSDRPRFTELVCSLSDVYQ 684
P+ RP F L +L +++
Sbjct: 370 RPATRPSFHTLHKTLENMHS 429
>07940
Length = 1336
Score = 117 bits (292), Expect = 3e-26, Method: Compositional matrix adjust.
Identities = 51/113 (45%), Positives = 78/113 (69%), Gaps = 4/113 (3%)
Frame = -3
Query: 518 KNSLKVLT---LVLYSLQICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSRYI 574
++ LK+LT L+ Y+ Q+ + M YL S C+HRD+A RN+LVA +K+ DFGL+R +
Sbjct: 374 QDMLKMLTPKDLISYAYQVARGMEYLASKQCIHRDLAARNVLVAEEYVLKIADFGLTRNL 195
Query: 575 EDEDYY-KASVTRLPIKWMSPESINFRRFTTASDVWMFAVCMWEILSFGKQPF 626
+ DYY K + RLP+KWM+PE++ R++T+ SDVW + V +WEI + G P+
Sbjct: 194 QQFDYYRKTTDGRLPVKWMAPEALFDRKYTSKSDVWSYGVLLWEIFTLGGNPY 36
>14116
Length = 1017
Score = 113 bits (283), Expect = 4e-25, Method: Compositional matrix adjust.
Identities = 61/185 (32%), Positives = 110/185 (59%), Gaps = 6/185 (3%)
Frame = -1
Query: 448 KGEKINVAVKTCKKDCTLDNK-EKFMSEAVIMKNLDHPHIVKLIGI---IEEEPTWIIME 503
KG+ I VAVKT + + + + F+ EA+IMK+ H +++ LIGI +++ P +++
Sbjct: 555 KGD-ILVAVKTLHNNNPREIELQSFLQEALIMKDFHHSNVLTLIGICLNLDDMPL-VVLP 382
Query: 504 LYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYLESINCVHRDIAVRNILVASPECV 563
+G+L Y+ +++ + L++Y + I + M YL + VHRD+A RN ++ V
Sbjct: 381 FMKHGDLLTYIRDDQHQPTIKDLIMYGVDIARGMDYLAGLKFVHRDLAARNCMLDEDFHV 202
Query: 564 KLGDFGLSRYIEDEDYYKA--SVTRLPIKWMSPESINFRRFTTASDVWMFAVCMWEILSF 621
K+ DFGL+R I +++YY + +LP+KWM+ ES+ + + +DVW + V +WE+L+
Sbjct: 201 KVADFGLARDIYEKEYYSSENKKAKLPVKWMALESLEKGNYDSKTDVWSYGVVLWELLTR 22
Query: 622 GKQPF 626
G
Sbjct: 21 GSDAL 7
>18996
Length = 491
Score = 111 bits (278), Expect = 1e-24, Method: Compositional matrix adjust.
Identities = 57/137 (41%), Positives = 84/137 (61%), Gaps = 6/137 (4%)
Frame = +2
Query: 546 VHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVTR-LPIKWMSPESINFRRFTT 604
+HRD+A RNILV CVK+ DFGL+++ + YY R +PIKW SPE+I +F++
Sbjct: 2 IHRDLAARNILVDR-SCVKISDFGLAQFANADGYYYGISQRDIPIKWYSPEAIETCKFSS 178
Query: 605 ASDVWMFAVCMWEILSFGKQPFFW----LENKDVIGVLEKGDRLPKPDLCPPVLYT-LMT 659
SDVW + V ++E+ S G+ P L ++ + L KG+RLPKP+LC +Y+ LM
Sbjct: 179 YSDVWSYGVTLFEMFSRGEIPNLLPGHDLTQEEFLNRLRKGERLPKPELCSDFVYSELMR 358
Query: 660 RCWDYDPSDRPRFTELV 676
CW P RP F +++
Sbjct: 359 PCWHEMPKSRPTFHQII 409
>22005
Length = 873
Score = 89.7 bits (221), Expect(2) = 1e-23, Method: Compositional matrix adjust.
Identities = 64/208 (30%), Positives = 96/208 (46%), Gaps = 45/208 (21%)
Frame = +1
Query: 457 KTCKKDCTLDNKEKFMSEAVIMKNLDHPHIVKLIGIIE-EEPTWIIMELYPYGELGHYL- 514
K K+D + D + F EA +M + DHP+IVKL+G+ +P ++ E G+L +L
Sbjct: 109 KMLKEDASEDLQSDFEREASLMADFDHPNIVKLLGVCAIGKPMCLLFEFMSKGDLNDFLR 288
Query: 515 -----------------------------------------ERNKNSLKVLTLVLY-SLQ 532
+R+ + + LY S Q
Sbjct: 289 LCSPENYNLPVSRSQNLVVDLEDGLRVEVEAEECEKDTQSEDRDCSGMLXTKDQLYISQQ 468
Query: 533 ICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKAS-VTRLPIKW 591
I MAYL + VHRD+A R + + + DFGL+R + DYY+ S +PI+W
Sbjct: 469 ISAGMAYLAQKDYVHRDLATRTVXSRTT*-S*ISDFGLARSVHSVDYYRGSEQDAIPIRW 645
Query: 592 MSPESINFRRFTTASDVWMFAVCMWEIL 619
M E+I + +F+T SDVW F V +WEIL
Sbjct: 646 MPLEAILYSKFSTQSDVWSFGVVLWEIL 729
Score = 39.3 bits (90), Expect(2) = 1e-23, Method: Compositional matrix adjust.
Identities = 15/49 (30%), Positives = 28/49 (57%)
Frame = +3
Query: 619 LSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTRCWDYDPS 667
+F QP++ L +++V+ ++ G L +P P +Y LM +CW P+
Sbjct: 726 FAFALQPYYGLTHEEVVNYVKAGKILEQPTKTPHQVYELMKQCWQRRPA 872
>08294
Length = 1849
Score = 106 bits (265), Expect = 4e-23, Method: Compositional matrix adjust.
Identities = 68/210 (32%), Positives = 104/210 (49%), Gaps = 13/210 (6%)
Frame = +2
Query: 484 PHIVKLIGIIEE-EPTWIIMELYPYGELGHYL--ERNKNS----LKVLTLVL-----YSL 531
P+IV +G+ E EP ++I E +G+L +L RN N +V L L
Sbjct: 887 PNIVHFMGVCREAEPHFLITEYCDWGDLKQFLLATRNDNGRGRGTRVPALALSQKLGMGQ 1066
Query: 532 QICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVTRLPIKW 591
Q+ M L + VH D+A RN+L+ S +K+ LS + +YY +P++W
Sbjct: 1067 QVAAGMEALSNQGLVHGDLAARNVLLTSRMQLKVARPALSGDVYASEYYPLHQRLVPLRW 1246
Query: 592 MSPESINFRRFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGD-RLPKPDLC 650
+ PE + TT DVW F V +WE+L P+ + +++V+ L+ L PD
Sbjct: 1247 LPPEGVLEDSATTCGDVWAFGVFLWEVLQLADLPYRLMSDEEVLRSLQHSQAALDSPD-A 1423
Query: 651 PPVLYTLMTRCWDYDPSDRPRFTELVCSLS 680
PP L +L+ RC PS RP F+E+ LS
Sbjct: 1424 PPALLSLLQRCTAQQPSQRPPFSEICSVLS 1513
>14477
Length = 493
Score = 87.8 bits (216), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 51/134 (38%), Positives = 79/134 (58%), Gaps = 2/134 (1%)
Frame = -1
Query: 451 KINVAVKTCKK-DCTLDNKEKFMSEAVIMKNLDHPHIVKLIGIIEEEPTWIIMELYPYGE 509
+I VA+K K D + + + EA +MK +DH HIV+LIG+ E E +++EL G
Sbjct: 409 EIPVAIKVLKNADLDPSVQSELIKEAEVMKKMDHMHIVRLIGLCEGETMMLVLELAKLGP 230
Query: 510 LGHYLERNKNSLKVLTLVLYSLQICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFG 569
L +L +NK+ L + ++ Q+ + M YLE+ VHRD+A RNIL+ K+ DFG
Sbjct: 229 LNKFLPKNKH-LPLWNILELMWQVSQGMEYLEANKFVHRDLAARNILLCDEHFAKISDFG 53
Query: 570 LSRYIEDE-DYYKA 582
+S+ + E +YY A
Sbjct: 52 MSKTLSRENNYYMA 11
>13305
Length = 549
Score = 85.5 bits (210), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 42/113 (37%), Positives = 64/113 (56%), Gaps = 3/113 (2%)
Frame = +2
Query: 585 TRLPIKWMSPESINFRRFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRL 644
TR+PI+WM+ ES+ +TT SDVW F V +WEI + G P+ + + + L+ G RL
Sbjct: 5 TRVPIRWMAVESLFNNTYTTQSDVWSFGVVLWEIFTLGGTPYSSTDTQQLFAFLKDGYRL 184
Query: 645 PKPDLCPPVLYTLMTRCWDYDPSDRPRFTELVCSLS---DVYQMEKDIAMEQE 694
+P LC Y +M +CW+ + RP F EL L D Q+ +++ E+E
Sbjct: 185 KRPKLCDQNTYAMMLQCWNENAQRRPTFPELCGRLQRMLDDCQVYMNLSTEEE 343
>17637
Length = 447
Score = 84.7 bits (208), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 46/122 (37%), Positives = 68/122 (55%), Gaps = 1/122 (0%)
Frame = +1
Query: 563 VKLGDFGLSRYIEDEDYYKASVTRL-PIKWMSPESINFRRFTTASDVWMFAVCMWEILSF 621
VKL D LSR + DY PIKW+S E++ + SDVW F V MWE+ +
Sbjct: 28 VKLTDSALSRDLFSGDYNCLGDGEYRPIKWLSLEALQKSHYNEGSDVWSFGVLMWEMCTL 207
Query: 622 GKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTRCWDYDPSDRPRFTELVCSLSD 681
GK P+ ++ ++ L+ G RL +P CP L+T+M CW P++RP F++L LS+
Sbjct: 208 GKLPYAEIDPYEMEHYLKDGYRLAQPFNCPDELFTIMAYCWASMPAERPSFSQLQICLSE 387
Query: 682 VY 683
+
Sbjct: 388 FH 393
>17253
Length = 483
Score = 82.8 bits (203), Expect = 6e-16, Method: Composition-based stats.
Identities = 50/160 (31%), Positives = 83/160 (51%), Gaps = 15/160 (9%)
Frame = -1
Query: 447 HKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKNLD-HPHIVKLIGIIE-EEPTWIIMEL 504
H + VAVKT + T K +F+ E IM+ L HP++V +G +P I+ME
Sbjct: 480 HARQWDTVAVKTHNEAATDAEKSEFLRELSIMRKLPRHPNVVSFMGCCTMSDPALILMEF 301
Query: 505 YPYGELGHYLERNK-----------NSLKVLTLVLYSLQICKAMAYLESINCVHRDIAVR 553
+G+L +L + + N L ++L + + MA++ + VHRD+A R
Sbjct: 300 CCHGDLLSFLRKRRPDRTVFLTSTANDLTARDFFSFALHVARGMAHVANNKIVHRDVAAR 121
Query: 554 NILVASPECVKLGDFGLSRYIEDEDYYKASVTR--LPIKW 591
N+L++ K+ DFGLSR + D++ V+R LP++W
Sbjct: 120 NVLISERNVCKVSDFGLSRRVGDQNDVYEIVSRRPLPLRW 1
>12721
Length = 821
Score = 77.4 bits (189), Expect = 3e-14, Method: Compositional matrix adjust.
Identities = 60/233 (25%), Positives = 110/233 (47%), Gaps = 8/233 (3%)
Frame = +1
Query: 445 TNHKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKNLDHPHIVKLIG--IIEEEPTWIIM 502
T+ G ++ V +K +E +E V+M++ HP+IV++ ++ +E W++M
Sbjct: 148 TSRDGRQMAVKKMDLRKQ---QRRELLFNEVVVMRDYHHPNIVEMYNSYLVNDE-LWVVM 315
Query: 503 ELYPYGELGHYLERNK-NSLKVLTLVLYSLQICKAMAYLESINCVHRDIAVRNILVASPE 561
E G L + N+ + +++ T+ L KA+A+L + +HRDI +IL++
Sbjct: 316 EFMEGGALTDIVTNNRMDEVQIATVCRACL---KALAFLHANGVIHRDIKSDSILLSHDG 486
Query: 562 CVKLGDFGLSRYIEDEDYYKASVTRLPIKWMSPESINFRRFTTASDVWMFAVCMWEILSF 621
VKL DFG + + + S+ P WM+PE I+ + D+W + + E++
Sbjct: 487 KVKLXDFGFCAQVTQDLQKRKSLVGTPY-WMAPEVISRLPYGPEVDIWSLGIMVMEMID- 660
Query: 622 GKQPFFWLENKDVIGVLEKGDRLPKPDL-----CPPVLYTLMTRCWDYDPSDR 669
+ PFF N+ + + + +P P L P L + R DP R
Sbjct: 661 AEPPFF---NEPPLQAMRRIRDMPPPKLRNTHKISPRLQGFIDRMLVRDPHQR 810
>01718
Length = 959
Score = 77.0 bits (188), Expect = 4e-14, Method: Compositional matrix adjust.
Identities = 62/255 (24%), Positives = 110/255 (43%), Gaps = 10/255 (3%)
Frame = +3
Query: 450 EKINVAVKTCKKDCTLDNKEKFMSEAVIMKNLDHPHIVKLIGI-IEEEPTWIIMELYPYG 508
+I V K + N+ + E ++ L H +I++ +G+ + E + E P G
Sbjct: 210 HRITGQVMALKMNTMTSNRHNMLREVQLLNRLQHANILRFMGVCVHEGQLHALTEYIPSG 389
Query: 509 ELGHYLERNKNSLKVLTLVLYSLQICKAMAYLESINCVHRDIAVRNILVASPEC----VK 564
L LE+ L + +L + + + YL S +HRD+ +NIL+ +
Sbjct: 390 NLEQLLEKKDEELPWTQRIQLTLGLARGLDYLHSTRFIHRDLTSKNILIRREDNHGYHAV 569
Query: 565 LGDFGLSRYIEDE-DYYKASVTRLPIKWMSPESINFRRFTTASDVWMFAVCMWEILSFGK 623
+ DFGL+ I D D K P WM+PE +N + +D++ + M EI +
Sbjct: 570 IADFGLATKIPDPLDKEKLPTVGSPY-WMAPEVLNGHFYNERADLFSVGIIMCEITARIP 746
Query: 624 QPFFWLENKDVIGVLEKGDRLPKPDL---CPPVLYTLMTRCWDYDPSDRPRFTELVCSLS 680
+ + GV D + ++ CP L +C DP RPR E++ L
Sbjct: 747 ADPDIMPRMNNFGV----DYVALSEMISYCPLDYLQLAFKCCQVDPQKRPRGVEIIEWLE 914
Query: 681 DVYQ-MEKDIAMEQE 694
+++ ++ DI Q+
Sbjct: 915 KIFKNLKNDIFTRQQ 959
>18921
Length = 697
Score = 72.0 bits (175), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 55/183 (30%), Positives = 88/183 (48%), Gaps = 4/183 (2%)
Frame = +2
Query: 447 HKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKNLDHPHIVKLIG-IIEEEPTWIIMELY 505
HK +A+K D L ++ + E IM+ D +IVK G + WI+ME
Sbjct: 92 HKETGQVLAIKQVPVDTDL---QEIIKEISIMQQCDSKYIVKYYGSYFKNTDLWIVMEYC 262
Query: 506 PYGELGHYLE-RNKNSLK--VLTLVLYSLQICKAMAYLESINCVHRDIAVRNILVASPEC 562
G + + RNK ++ + T++ Y+L K + YL S +HRDI NIL+ +
Sbjct: 263 GAGSVSDIMRLRNKTLVEREIATILYYTL---KGLXYLHSRRKIHRDIKAGNILLNNEGH 433
Query: 563 VKLGDFGLSRYIEDEDYYKASVTRLPIKWMSPESINFRRFTTASDVWMFAVCMWEILSFG 622
KL DFG++ + D + +V P WM+PE I + +D+W + E ++ G
Sbjct: 434 AKLADFGVAGQLTDTMAKRNTVIGTPY-WMAPEVIQEIGYDCVADIWSLGITALE-MAEG 607
Query: 623 KQP 625
K P
Sbjct: 608 KPP 616
>19301
Length = 712
Score = 68.6 bits (166), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 38/95 (40%), Positives = 53/95 (55%), Gaps = 1/95 (1%)
Frame = +2
Query: 478 MKNLDHPHIVKLIGIIEEEPTW-IIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKA 536
++ L+HP+I+ G+ + P + IIME PYG+L L K L L +S QI
Sbjct: 431 LRKLNHPNIISFKGVCTQAPCYCIIMEYCPYGQLYEVLRDGKEIPPALVLD-WSKQIASG 607
Query: 537 MAYLESINCVHRDIAVRNILVASPECVKLGDFGLS 571
M YL S +HRD+ N+LVA + VK+ DFG S
Sbjct: 608 MNYLHSHKIIHRDLKSPNVLVAKNDVVKISDFGTS 712
>27546
Length = 426
Score = 65.9 bits (159), Expect = 9e-11, Method: Composition-based stats.
Identities = 42/134 (31%), Positives = 71/134 (52%), Gaps = 3/134 (2%)
Frame = -1
Query: 446 NHKGEKINVAVKTCKK-DCTLDNKEKFM-SEAVIMKNLDHPHIVKLIGIIEEEPT-WIIM 502
+ G +N+A K K +D +KF E I+ LDHP+I+++ I++ P +I M
Sbjct: 420 DESGHGVNLACKIIDKAKAPIDFVKKFFPRELEILTRLDHPNIIQIHSILQRGPKIFIFM 241
Query: 503 ELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYLESINCVHRDIAVRNILVASPEC 562
G++ ++++ + T V + Q+ KA+ YL S + HRD+ NIL++
Sbjct: 240 RYAEKGDMLSHIKKTGPIDEAQTKVWF-FQMAKALQYLHSHDIAHRDLKCENILLSKRLN 64
Query: 563 VKLGDFGLSRYIED 576
VK+ DFG +RY D
Sbjct: 63 VKIADFGFARYCRD 22
>14420
Length = 528
Score = 65.5 bits (158), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 44/162 (27%), Positives = 78/162 (48%), Gaps = 2/162 (1%)
Frame = +2
Query: 468 KEKFMSEAVIMKNLDHPHIVK-LIGIIEEEPTWIIMELYPYGELGHYL-ERNKNSLKVLT 525
KE ++E ++M+ +P+IV L + E W++ME G L + E + ++
Sbjct: 32 KELIINEILVMRENQNPNIVNYLDSYLVGEELWVVMEFLAGGSLTDVVTETCMDEGQIAA 211
Query: 526 LVLYSLQICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVT 585
+ LQ A+ +L +HRDI NIL+ VKL DFG + E ++++
Sbjct: 212 VCRECLQ---ALEFLHENQVIHRDIKSDNILLGMDGSVKLTDFGFCAQLSPEQSKRSTMV 382
Query: 586 RLPIKWMSPESINFRRFTTASDVWMFAVCMWEILSFGKQPFF 627
P WM+PE + +++ D+W V E++ G+ P+
Sbjct: 383 GTP-YWMAPEVVTRKQYGPTVDIWSLGVMCIEMIE-GEPPYL 502
>13066
Length = 551
Score = 60.5 bits (145), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 41/126 (32%), Positives = 66/126 (52%), Gaps = 3/126 (2%)
Frame = +3
Query: 449 GEKINVAVKTCKKD-CTLDNKEKFM-SEAVIMKNLDHPHIVKLIGIIEEEP-TWIIMELY 505
G I +A K K+ +D EKF E ++ LDHP+I+++ I++ P +I M
Sbjct: 45 GRNIKLACKIIDKEKAPVDFVEKFFPRELDLLTKLDHPYIIQIHSILQRXPKNFIFMRFA 224
Query: 506 PYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYLESINCVHRDIAVRNILVASPECVKL 565
G+L Y++ +K ++ Q+ A+ YL S + HRD+ NIL++S VKL
Sbjct: 225 ERGDLLTYIQE-VGFVKEKQAKIWFYQMTTALNYLHSYDVAHRDLKCENILLSSHFNVKL 401
Query: 566 GDFGLS 571
DFG +
Sbjct: 402 ADFGFA 419
>00300
Length = 2318
Score = 59.3 bits (142), Expect = 7e-09, Method: Compositional matrix adjust.
Identities = 55/218 (25%), Positives = 98/218 (44%), Gaps = 8/218 (3%)
Frame = -1
Query: 474 EAVIMKNLDHPHIVKLIGI-IEEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQ 532
E I + + H ++VK G+ + ++ + ME Y + G E K L + Y+ +
Sbjct: 1511 EIKIFEGIQHENLVKYYGVEVHKDEMLMFME---YCDTGTIEEAAKMGLPEYLIRRYTRE 1341
Query: 533 ICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVTRL--PIK 590
I A+ +L + VHRDI NI + S VKLGDFG S ++ L
Sbjct: 1340 IVLAVNHLHENSIVHRDIKGANIFLTSNGHVKLGDFGCSVKLKSHTTMPGEFHNLVGTTA 1161
Query: 591 WMSPESI---NFRRFTTASDVWMFAVCMWEILSFGKQPFFWLENK-DVIGVLEKGDRLPK 646
+M+PE + + A+D+W + E ++ GK+P+ L+N ++ + G +
Sbjct: 1160 YMAPEVFTQNDQGGYGRAADIWSLGCVVIE-MATGKRPWHDLDNNYQIMYKVGIGHKPAV 984
Query: 647 PDLCPPVLYTLMTRCWDYDPSDRPRFTELV-CSLSDVY 683
PD + +DP+ R ++L+ + + VY
Sbjct: 983 PDSLSVEGKHFLDLIMCHDPAQRALASQLLDHTFTKVY 870
>31885
Length = 529
Score = 58.9 bits (141), Expect = 9e-09, Method: Compositional matrix adjust.
Identities = 44/156 (28%), Positives = 83/156 (53%), Gaps = 6/156 (3%)
Frame = -2
Query: 477 IMKNLDHPHIVKL-IGIIEEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICK 535
++ LDHP +V L +EE +++++L+ G+L +++++ + S + + Y Q+
Sbjct: 513 MLTRLDHPFLVNLWYAFQDEEDLFMVVDLFLGGDLRYHMQQ-EVSFREDCVKFYLCQLAL 337
Query: 536 AMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVTRLPIKWMSPE 595
+ YL S VHRDI NIL+ + DF ++ +ED++ ++ P +M+PE
Sbjct: 336 VLDYLRSQKIVHRDIKPDNILLDEQGHCHVTDFNIATQLEDDELATSTSGTRP--YMAPE 163
Query: 596 ----SINFRR-FTTASDVWMFAVCMWEILSFGKQPF 626
+IN RR + D W V ++E+L ++PF
Sbjct: 162 VYGVAINERRGYGFPVDWWSLGVSLFELLK-KRRPF 58
>07833
Length = 1504
Score = 58.2 bits (139), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 52/221 (23%), Positives = 101/221 (45%), Gaps = 15/221 (6%)
Frame = -3
Query: 471 FMSEAVIMKNLDHPHIVKLIGIIEEEPTWIIM-ELYPYGELGHYLERNKNSLKVLTLVL- 528
FM E ++ +HP+++ ++ + P +++ + P+G L + L + L
Sbjct: 1478 FMEEFPRLRIFNHPNVLPVLACCNQPPNLVLISQFMPFGSLYNTLHGESGIVVDQNQSLR 1299
Query: 529 YSLQICKAMAYLESINCVHRDIAVRNILVASPEC---------VKLGDFGLSRYIEDEDY 579
+++ I + M +L S+ + + N L+ S + + D+ S + + + Y
Sbjct: 1298 FAMDIARGMEFLHSM-----EPTIPNFLLTSKHVMIDEDLTARINMADYCFSFHEKGKVY 1134
Query: 580 YKASVTRLPIKWMSPESINFRR---FTTASDVWMFAVCMWEILSFGKQPFFWLENKDV-I 635
A WM+PE++ R T A+D+W FA+ MWE L + PF L + +V +
Sbjct: 1133 SPA--------WMAPEALQRRPDDINTRAADMWSFAILMWE-LETREVPFAELSSMEVGM 981
Query: 636 GVLEKGDRLPKPDLCPPVLYTLMTRCWDYDPSDRPRFTELV 676
V +G R+ P + L+ C + +P RPRF ++
Sbjct: 980 KVALEGLRISIPPGISLHMSRLIKICMNEEPGKRPRFDMII 858
>30755
Length = 1137
Score = 55.8 bits (133), Expect = 8e-08, Method: Compositional matrix adjust.
Identities = 30/101 (29%), Positives = 55/101 (54%), Gaps = 1/101 (0%)
Frame = +2
Query: 528 LYSLQICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVTRL 587
Y +I A+ YL S ++RD+ + N+L+ +K+ DFGL + ED Y + + T
Sbjct: 44 FYGAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCK--EDITYGRTTKTFC 217
Query: 588 PI-KWMSPESINFRRFTTASDVWMFAVCMWEILSFGKQPFF 627
++++PE ++ + A D W V M+E++ G+ PF+
Sbjct: 218 GTPEYLAPEVLDDNDYGRAVDWWGTGVVMYEMIC-GRLPFY 337
>21079
Length = 878
Score = 54.7 bits (130), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 40/146 (27%), Positives = 69/146 (47%), Gaps = 3/146 (2%)
Frame = +1
Query: 483 HPHIVKLIGIIEEEPTWI-IMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYLE 541
HP ++ L E T + +ME GEL + R+ L V + QIC + Y+
Sbjct: 1 HPKLLMLWDAFEAPRTMVLVMEFVGAGELFERVIRDDFVLTERDCVHFVRQICSGVGYMH 180
Query: 542 SINCVHRDIAVRNILVASPEC--VKLGDFGLSRYIEDEDYYKASVTRLPIKWMSPESINF 599
+ + +H D+ N+L S +K+ DFGL+R+ + D V ++++PE +N+
Sbjct: 181 TQSILHLDLKPENVLCVSDNSNQIKIIDFGLARFYKPGD--SLQVLFGTPEFIAPEVVNY 354
Query: 600 RRFTTASDVWMFAVCMWEILSFGKQP 625
+D+W V + +LS G P
Sbjct: 355 DEINFTTDMWSIGVICYILLS-GLSP 429
>29581
Length = 1278
Score = 53.9 bits (128), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 43/158 (27%), Positives = 73/158 (46%), Gaps = 6/158 (3%)
Frame = -2
Query: 475 AVIMKNLDHPHIVKLIGII---EEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSL 531
+ + NL H +IV+L ++ + +++ME Y +L L+ + L
Sbjct: 1202 STFLLNLRHQNIVQLQEVVVGKSLDSLFLVME-YCEQDLASLLDNMPAPFSESQVKCIVL 1026
Query: 532 QICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSR-YIEDEDYYKASVTRLPIK 590
Q+ K + YL +HRD+ V N+L+ CVK+ DFGL+R Y + + V L
Sbjct: 1025 QLLKGLRYLHEAFIIHRDLKVSNLLMTDKGCVKIADFGLARNYGKPQKPMTPKVVTL--- 855
Query: 591 WMSPESINF--RRFTTASDVWMFAVCMWEILSFGKQPF 626
W + F + +TA D+W + E+L G +P
Sbjct: 854 WYRAPELLFGSKTHSTAIDMWSAGCILGELL--GHKPL 747
>19094
Length = 898
Score = 53.1 bits (126), Expect = 5e-07, Method: Composition-based stats.
Identities = 33/105 (31%), Positives = 54/105 (51%), Gaps = 2/105 (1%)
Frame = +1
Query: 516 RNKNSLK--VLTLVLYSLQICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSRY 573
RNK ++ + T++ Y+L K + YL S +HRDI NIL+ + KL DFG++
Sbjct: 37 RNKTLVEREIATILYYTL---KGL*YLHSRRKIHRDIKAGNILLNNEGHAKLADFGVAGQ 207
Query: 574 IEDEDYYKASVTRLPIKWMSPESINFRRFTTASDVWMFAVCMWEI 618
+ D + +V P WM+PE I + +D+W + E+
Sbjct: 208 LTDTMAKRNTVIGTPY-WMAPEVIQEIGYDCVADIWSLGITALEM 339
>15910
Length = 1361
Score = 52.0 bits (123), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 40/123 (32%), Positives = 64/123 (52%), Gaps = 6/123 (4%)
Frame = +2
Query: 511 GHYLERNKNSLKVLTLVLYSLQICKAMAYLESINCVHRDIAVRNILVASPEC------VK 564
G Y E K++ + ++ +L+ +Q Y+ + VHRD+ N+L EC +K
Sbjct: 449 GQYTE--KDAARAISDILHGVQ------YIHANGVVHRDLKPENLLY---ECMTDDSKLK 595
Query: 565 LGDFGLSRYIEDEDYYKASVTRLPIKWMSPESINFRRFTTASDVWMFAVCMWEILSFGKQ 624
L DFGLSR IE E ++V P + +PE + ++T + D+W V + IL G +
Sbjct: 596 LADFGLSRIIEPE-VQMSTVCGTP-GYCAPEVLKGDKYTPSVDMWSVGVIAY-ILLCGYE 766
Query: 625 PFF 627
PFF
Sbjct: 767 PFF 775
>19761
Length = 473
Score = 51.6 bits (122), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 38/132 (28%), Positives = 65/132 (49%), Gaps = 9/132 (6%)
Frame = -3
Query: 526 LVLYSLQICKAMAYLESINCV--HRDIAVRNILVASPECVKLGDFGLSRYIED-EDYYKA 582
+V + +Q A+ Y+ + V HRD+ +NI V V+LGD GL+R + D+ +
Sbjct: 417 IVCWLMQTASALNYMHTHTPVILHRDLKPQNIYVTEKGDVRLGDLGLARKLTGPADFATS 238
Query: 583 SVTRLPIKWMSPESINFRRFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVL---- 638
V I ++SPE ++ + + + SD+W ++I GK+ D +GV+
Sbjct: 237 QVGT--IMYLSPEILSQQPYNSKSDIWSLGCVFYDIT--GKK------GSDEMGVMFLLV 88
Query: 639 --EKGDRLPKPD 648
G +LP PD
Sbjct: 87 QVMGGRKLPLPD 52
>01707
Length = 757
Score = 50.8 bits (120), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 47/184 (25%), Positives = 84/184 (45%), Gaps = 5/184 (2%)
Frame = +1
Query: 468 KEKFMSEAVIMKNLDHPHIVKLIGIIEEEPTWIIMELYPYGELGHYLERNKNSLKVLTLV 527
K+ M E ++K L HP++V+LI + + ++ Y L + L+R L +
Sbjct: 193 KKIAMREIRMLKQLKHPNLVRLIEVFRRKKRLHLVFDYVDHTLLNELDRYPRGLPEPMVK 372
Query: 528 LYSLQICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSRYIE--DEDYYKASVT 585
Q A+ + N +HRD+ NIL+ VKL DFG +R + ++Y T
Sbjct: 373 RIIYQTLLAVNFCHQYNTIHRDVKPENILITRQGQVKLCDFGFARILTGPGDEYTDYVAT 552
Query: 586 RLPIKWMSPE-SINFRRFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEK--GD 642
R + +PE + ++ DVW E+L+ G+ + + D + ++ K GD
Sbjct: 553 RW---YRAPELLVGDTQYGPPVDVWAIGCVFAELLT-GQALWPGRSDVDQLHLIRKTLGD 720
Query: 643 RLPK 646
+P+
Sbjct: 721 LIPR 732
>14126
Length = 1265
Score = 50.1 bits (118), Expect = 5e-06, Method: Compositional matrix adjust.
Identities = 55/208 (26%), Positives = 93/208 (44%), Gaps = 26/208 (12%)
Frame = +3
Query: 461 KDCTLDNKEKFM-----SEAVIMKNLD---HPHIVKLIG-----IIEEEPTWIIMELYPY 507
K L+N E+ M E ++K L+ HP++V+L+ I + E ++ Y
Sbjct: 285 KRIRLNNTEEGMPMMAIREISMLKQLEQYEHPNVVRLLDVSHNTITDREIRLNLVFEYIE 464
Query: 508 GELGHYLER------NKNSLKVLTLVLYSLQICKAMAYLESINCVHRDIAVRNILVASPE 561
+L YL + + +K L L Q+ + +L S VHRD+ +N+L++
Sbjct: 465 HDLATYLAKCPSPGLGPDRIKDLML-----QLLNGVDFLHSNRIVHRDLKPQNLLISKDG 629
Query: 562 CVKLGDFGLSRYIEDEDYYKASVTRLPIKWM-SPESINFRRFTTASDVWMFAVCMWEILS 620
+KL DFGL+R ++ A T + W SPE + + T+ D+W E+ +
Sbjct: 630 RLKLADFGLARIYS---FHMALTTVVVTLWYRSPEVLMQAEYGTSVDIWSCGCIFAELFT 800
Query: 621 F-----GKQPFFWLENK-DVIGVLEKGD 642
G F L+ +VIG+ GD
Sbjct: 801 RRALFKGSSEFDQLKKIFEVIGLPPAGD 884
>18484
Length = 635
Score = 49.7 bits (117), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 25/114 (21%), Positives = 58/114 (50%)
Frame = +1
Query: 513 YLERNKNSLKVLTLVLYSLQICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSR 572
Y + + K Y+ +I + +L ++RD+ + N+++ S +K+ DFG+ +
Sbjct: 10 YRIQQEGKFKEPVAAFYAAEIAVGLFFLHDQGIIYRDLKLDNVMLDSEGHIKIADFGMCK 189
Query: 573 YIEDEDYYKASVTRLPIKWMSPESINFRRFTTASDVWMFAVCMWEILSFGKQPF 626
D + P +++PE + ++ ++ + D W + V ++E+L+ G+ PF
Sbjct: 190 EGMTGDATTRTFCGTP-DYIAPEIVLYQPYSKSVDWWAYGVLLFEMLA-GQPPF 345
>13212
Length = 1067
Score = 49.7 bits (117), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 43/188 (22%), Positives = 79/188 (42%), Gaps = 10/188 (5%)
Frame = -1
Query: 499 WIIMELYP---YGELGHYLERNKNSLKVLTLVLYSLQICKAMAYLESINCVHRDIAVRNI 555
W I++++ +G L + + + + ++C A+ +L + +HRDI N+
Sbjct: 1064 WXIVDVFRVLWWGALDSIMVDLEKPMTEAQICYVCHEMCMALDFLHRHHVIHRDIKAGNV 885
Query: 556 LVASPECVKLGDFGLSRYIEDEDYYKASVTRLPIKWMSP-----ESINFRRFTTASDVWM 610
L+ VKL DFG+S + + P WM+P E++ + +D+W
Sbjct: 884 LLTIDGEVKLADFGVSAKNTQTQQKRDTFIGTPY-WMAPEVVLCETLKDTPYDFKADIWS 708
Query: 611 FAVCMWEILSFGKQPFFWLENKDVIGVLEKGD--RLPKPDLCPPVLYTLMTRCWDYDPSD 668
V + E + P + V+ + K D L KP + + +C DP+
Sbjct: 707 LGVTLIEFAQI-EPPNKEMHPMRVLIKIHKSDPPTLEKPKKWTKLFKDFIAKCLVKDPNL 531
Query: 669 RPRFTELV 676
RP EL+
Sbjct: 530 RPTAAELL 507
>25550
Length = 941
Score = 49.3 bits (116), Expect = 8e-06, Method: Compositional matrix adjust.
Identities = 27/98 (27%), Positives = 53/98 (54%), Gaps = 3/98 (3%)
Frame = +3
Query: 610 MFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTRCWDYDPSDR 669
M A +W++ G ++ +V +LE+G R+ +P P +Y LM +CW +DP +R
Sbjct: 12 MGACDIWDVXYPG------VDLTEVYHLLERGYRMERPQGTPADVYILMLKCWQWDPKER 173
Query: 670 PRFTELVCSLSDVYQ---MEKDIAMEQERNARYRTPKI 704
P F E+ L ++++ + +++ E E+N + P +
Sbjct: 174 PTFKEIHYLLENMFEKSSISEEVEKELEKNDKKLIPTL 287
>00715
Length = 1788
Score = 48.5 bits (114), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 50/249 (20%), Positives = 100/249 (40%), Gaps = 36/249 (14%)
Frame = +1
Query: 468 KEKFMSEAVIMK-NLDHPHIVKLIGIIE----EEPTWIIMELYPYGELGHYLERNKNSLK 522
++ + +E + + L H ++V ++G E+ W+ ME L L ++ +
Sbjct: 55 RQSYSNELLAFRCGLRHVNVVSILGATSLHRFEDGAWLAMEYVGPLNLQTILNDHQQDID 234
Query: 523 VLTLVLYSLQICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSRYI-------- 574
+ +LQ+ + + YL SIN VH D+ N L+ +++ DFG +
Sbjct: 235 SSMRLSLALQMARGLHYLHSINIVHLDLKPANCLLTRDLKLRIADFGCCHQLTPTGLDMG 414
Query: 575 EDEDYYKASVTRL-------------PIKWMSPESINFRRFTTASDVWMFAVCMWEILSF 621
E E + L + + +PE + + + SDV+ + +W++ +
Sbjct: 415 EREGGMAGNELELTPVQGAWKNELAGTLAYRAPELLKGLQPSVRSDVYSLGITLWQMCTR 594
Query: 622 GKQPFFWLENKDVIGVLEKGDRLPKPDLCPP----------VLYTLMTRCWDYDPSDRPR 671
+ P+ + V+ + D P CPP + L T+CW DRP
Sbjct: 595 -QGPYEGVPAHAVVYQVVSKDLRP----CPPPSTEDDPFEVMFRDLYTQCWARRVEDRPT 759
Query: 672 FTELVCSLS 680
++V ++
Sbjct: 760 SLDVVHAIG 786
>01756
Length = 1858
Score = 48.1 bits (113), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 57/233 (24%), Positives = 93/233 (39%), Gaps = 22/233 (9%)
Frame = -3
Query: 461 KDCTLDN-KEKF----MSEAVIMKNLDHPHIVKLIGIIEEEPTWIIMELYPYGELGHYLE 515
K +DN KE F + E I++ L+H ++V LI I + T + + + E
Sbjct: 1649 KKVLMDNEKEGFPITALREIKILQLLNHENVVDLIEICSTKATSANRYKSMFYLVFEFCE 1470
Query: 516 RNKNSLKVLTLVLYSL--------QICKAMAYLESINCVHRDIAVRNILVASPECVKLGD 567
+ L V+++L Q+ + Y+ +HRD+ NIL+ +KL D
Sbjct: 1469 HDLAGLLSNMSVVFNLPEIKEVMKQLMNGLYYIHRNKILHRDMKAANILITKQGVLKLAD 1290
Query: 568 FGLSRY----IEDEDYYKASVTRLPIKWMSPESINF--RRFTTASDVWMFAVCMWEILSF 621
FGL+R + + Y V L W P + R ++TA D W M E+
Sbjct: 1289 FGLARAFSVNLRQPNRYTNRVVTL---WYRPPELLLGDRNYSTAIDQWGAGCIMAEM--- 1128
Query: 622 GKQPFFWLENKDVIGVLEKGDRLPKPDLC---PPVLYTLMTRCWDYDPSDRPR 671
W N + G E+ LC P ++ + R Y+ D P+
Sbjct: 1127 ------WTRNPIMQGTTEQNQLTLITQLCGSITPEVWPGVERLELYNSLDLPQ 987
>12672
Length = 773
Score = 46.2 bits (108), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 38/158 (24%), Positives = 64/158 (40%), Gaps = 16/158 (10%)
Frame = +3
Query: 534 CKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGL---SRYIEDEDYYKASVTRLPIK 590
+ YL VHRDI NIL+ S K+GDF + E + ASV
Sbjct: 21 ASGIQYLNDNGHVHRDIKTANILLDSEYTAKVGDFATVVSAPSGEGKTVQNASVVIGTAA 200
Query: 591 WMSPESINFRRFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPK---- 646
+++PE+I+F +T D + F V + E+++ + E + + + + P+
Sbjct: 201 YLAPEAIHF-DVSTKLDSYSFGVVLLEVITGLVAQDYSREERTLSSHIMENVEEPEEIHD 377
Query: 647 ---------PDLCPPVLYTLMTRCWDYDPSDRPRFTEL 675
PD LY + RC + RP ++
Sbjct: 378 FVDQSAGTWPDGAVDKLYDISMRCLNLSKKQRPNVKDI 491
>32264
Length = 287
Score = 45.1 bits (105), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 21/45 (46%), Positives = 26/45 (57%)
Frame = +1
Query: 638 LEKGDRLPKPDLCPPVLYTLMTRCWDYDPSDRPRFTELVCSLSDV 682
+E G RL + P +Y LM RCW+Y P RP F EL SL D+
Sbjct: 1 IEDGYRLQQNPQTPDSVYKLMLRCWEYVPEKRPHFKELYTSLKDI 135
>26711
Length = 405
Score = 45.1 bits (105), Expect = 1e-04, Method: Composition-based stats.
Identities = 30/99 (30%), Positives = 52/99 (52%), Gaps = 4/99 (4%)
Frame = -2
Query: 532 QICKAMAYLESINCVHRDIAVRNILVASP--ECVKLGDFGLSR--YIEDEDYYKASVTRL 587
Q+ + ++ + VH D+ N+L++ + V+L DFGL+R Y E +
Sbjct: 392 QVLDILQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARKLYPPQETFLNHGTP-- 219
Query: 588 PIKWMSPESINFRRFTTASDVWMFAVCMWEILSFGKQPF 626
+ SPE+++ + +TASDVW V + +LS G+ PF
Sbjct: 218 --GFTSPEALDVKPISTASDVWGVGVLAYILLS-GQSPF 111
>01060
Length = 1800
Score = 44.3 bits (103), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 41/163 (25%), Positives = 76/163 (46%), Gaps = 7/163 (4%)
Frame = +1
Query: 472 MSEAVIMKNLDHPHIVKLIGII-EEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVL-- 528
+ E +++ L H +IV L +I E+E +++ E +L Y+++ + VL L
Sbjct: 214 IREIAMLRELRHTNIVCLEDVIMEDERLFLVFEFLSM-DLKMYIDKFPEGV-VLDRRLVK 387
Query: 529 -YSLQICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSRYIE--DEDYYKASVT 585
Y QI + + VHRD+ +N+L+ +K+ DFG++R Y VT
Sbjct: 388 SYVFQIVTGIXFCHQRRIVHRDLKPQNLLINHTGAIKIADFGMARTFALPVRAYTHEVVT 567
Query: 586 RLPIKWMSPESI-NFRRFTTASDVWMFAVCMWEILSFGKQPFF 627
+ + +PE + +++T DVW ++L + P F
Sbjct: 568 ---LWYRAPEILMGASKYSTPVDVWSIGTIFADMLI--RTPIF 681
>04591
Length = 1117
Score = 44.3 bits (103), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 27/92 (29%), Positives = 42/92 (45%), Gaps = 3/92 (3%)
Frame = -2
Query: 532 QICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSR-YIEDEDYYKASVTRLPIK 590
Q+ + Y+ + +HRDI NIL+ +KL DFGLSR +++ K R+
Sbjct: 873 QLLNGLFYIHTKQILHRDIKAANILLTRDGVLKLADFGLSRPWVKS----KRLTNRVVTL 706
Query: 591 WMSPESINF--RRFTTASDVWMFAVCMWEILS 620
W P + R + D+W M E+ S
Sbjct: 705 WYRPPELLLGEREYGPEIDMWGVGCIMAEMWS 610
>03240
Length = 1683
Score = 43.1 bits (100), Expect = 5e-04, Method: Compositional matrix adjust.
Identities = 38/140 (27%), Positives = 66/140 (47%), Gaps = 9/140 (6%)
Frame = -3
Query: 455 AVKTCKKDCTLDNKE--KFMSEAVIMKNLDHPHIVKLIGIIEEEP-TWIIMELYPYGELG 511
A+KT +K L + +E I+ D+ +VKL ++ + +M+ P G+L
Sbjct: 1204 AMKTLRKSDVLKRNQVAHVKAERDILAEADNEWVVKLYYSFQDHNYLYFVMDYVPGGDLM 1025
Query: 512 HYLERNKNSLKVLTLVL---YSLQICKAMAYLESINCVHRDIAVRNILVASPECVKLGDF 568
L R +++L L Y ++ +A+ + + +HRDI NIL+ +KL DF
Sbjct: 1024 GLLIR----MEILDEPLARFYVAELVQAIESVHRMGFIHRDIKPDNILIDRNGHIKLTDF 857
Query: 569 GLS---RYIEDEDYYKASVT 585
GL R+ + YY+ T
Sbjct: 856 GLCTGFRWTHNSKYYQRDGT 797
>04138
Length = 800
Score = 41.6 bits (96), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 45/177 (25%), Positives = 71/177 (40%), Gaps = 7/177 (3%)
Frame = +1
Query: 537 MAYLESINCVHRDIAVRNILVASPECVKLGDFGLSRY----IEDEDYYKASVTRLPIKWM 592
+ Y+ +HRD+ NIL+ +KL DFGL+R + + Y V L W
Sbjct: 52 LYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTL---WY 222
Query: 593 SPESINF--RRFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLC 650
P + R ++TA D W M E+ W N + G E+
Sbjct: 223 RPPELLLGDRNYSTAIDQWGAGCIMAEM---------WTRNPIMQGTTEQNQ-------- 351
Query: 651 PPVLYTLMTR-CWDYDPSDRPRFTELVCSLSDVYQMEKDIAMEQERNARYRTPKILE 706
TL+T+ C P P T+ LS +Q++ +A ++ R R +IL+
Sbjct: 352 ----LTLITQLCGSITPEVWPGVTQ----LSMYHQIKGALAAGRKNIIRDRFARILK 498
>35671
Length = 567
Score = 41.6 bits (96), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 18/50 (36%), Positives = 29/50 (58%)
Frame = -3
Query: 639 EKGDRLPKPDLCPPVLYTLMTRCWDYDPSDRPRFTELVCSLSDVYQMEKD 688
+KG+RL KP C Y +M +CW +RP F +LV + ++Y+ +D
Sbjct: 565 QKGNRLAKPISCTDEAYKVMLQCWTESREERPTFKKLVPVMENLYRSHRD 416
>01966
Length = 1735
Score = 41.2 bits (95), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 38/159 (23%), Positives = 73/159 (45%), Gaps = 9/159 (5%)
Frame = -1
Query: 447 HKGEKINVAVKTCKKDCTLDN-KEKFMSEAVIMKNLDHPHIVKLIGII-EEEPTWIIMEL 504
H+ +A+K + + D + E +++ L H +IV L +I E+E +++ E
Sbjct: 1648 HRATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTNIVCLEDVIMEDERLFLVFEF 1469
Query: 505 YPYGELGHYLERNKNSLKVLTLVL--YSLQICKAMAYLESINCVHRDIAVRNILVASPEC 562
+L Y+++ + + ++ Y QI + + VHRD+ +N+L+
Sbjct: 1468 LSM-DLKMYIDKFPEGVVLDRRLVKSYVFQIVTGINFCHQRRIVHRDLKPQNLLINHTGA 1292
Query: 563 VKLGDFGLSRY--IEDEDYYKASVT---RLPIKWMSPES 596
+K+ DFG++R + Y VT R P M P+S
Sbjct: 1291 IKIADFGMARTFALPVRAYTHEVVTLWYRAPEILMGPQS 1175
>07933
Length = 728
Score = 39.3 bits (90), Expect = 0.008, Method: Compositional matrix adjust.
Identities = 14/29 (48%), Positives = 20/29 (68%)
Frame = +3
Query: 647 PDLCPPVLYTLMTRCWDYDPSDRPRFTEL 675
P+ CP +LY +M +CW +PS RP F +L
Sbjct: 3 PNYCPNLLYNIMMQCWSAEPSARPTFHKL 89
>07836
Length = 1478
Score = 38.1 bits (87), Expect = 0.018, Method: Compositional matrix adjust.
Identities = 47/162 (29%), Positives = 73/162 (45%), Gaps = 24/162 (14%)
Frame = -1
Query: 481 LDHPHIVKLIGI-IEEEPTW----IIMELYPYGELGHYL-ERNKNSLKVLTLVLYSLQIC 534
L H +I+ I I+ +W +I + + G L YL R +S ++L L +S
Sbjct: 1394 LRHENILGFIAADIKGTGSWTQLFLITDYHENGSLHDYLLSRVLDSSEMLALA-HSAICG 1218
Query: 535 KAMAYLESINC------VHRDIAVRNILVASPECVKLGDFGLS-RYIEDEDYYKASVTRL 587
A ++E HRDI +NILV + D GL+ RYI + + + V
Sbjct: 1217 LAHLHIEIFGTRGKPAIAHRDIKSKNILVKKNGTCCIADLGLAVRYISESN--EVDVAPN 1044
Query: 588 P----IKWMSPESI-------NFRRFTTASDVWMFAVCMWEI 618
P ++M+PE + NF F A D++ F + MWEI
Sbjct: 1043 PRQGTKRYMAPEVLEMLLNVKNFDAFKQA-DMYAFGLVMWEI 921
>28157
Length = 400
Score = 37.4 bits (85), Expect = 0.035, Method: Compositional matrix adjust.
Identities = 34/127 (26%), Positives = 59/127 (46%), Gaps = 8/127 (6%)
Frame = +3
Query: 453 NVAVKTCKKDCTLDNKEKFMSEAVIMKNLDHPHIVKLIGIIEEEPTWIIMELYPYGELGH 512
+VAVK + + K+ FM E + + HP+IV L G + P ++ME G L +
Sbjct: 6 DVAVKRIESE---QEKKSFMQELKQLSRVSHPNIVCLYGACRDHPVCLVMEYAEGGSLYN 176
Query: 513 YLERN--KNSLKVLTLVLYSLQICKAMAYLESIN---CVHRDIAVRNILVASPEC---VK 564
L + + + + LQ + YL + +HRD+ N+L+ +C +K
Sbjct: 177 VLHGSGPQPQYTAAHAMNWLLQCALGVEYLHGMKPKALIHRDLKPPNLLLI--QCGTKLK 350
Query: 565 LGDFGLS 571
+ DFG +
Sbjct: 351 ICDFGTA 371
>32359
Length = 928
Score = 36.6 bits (83), Expect = 0.050, Method: Compositional matrix adjust.
Identities = 30/103 (29%), Positives = 51/103 (49%), Gaps = 10/103 (9%)
Frame = -1
Query: 454 VAVKTCKKDCTLDNKEKFMSEAVIMKNLDHPHIVKLIGII-------EEEPTWIIMELYP 506
VA+K +D N+E IM+ L+H +IVKL +E +++E P
Sbjct: 346 VAIKKVLQDKRFKNRE-----LQIMRKLEHQNIVKLKFFFYSSGEKKDEVFLNLVLEYVP 182
Query: 507 ---YGELGHYLERNKNSLKVLTLVLYSLQICKAMAYLESINCV 546
Y HY ++K ++ +L + LY Q+ +++AY+ S CV
Sbjct: 181 ETVYRVARHY-SKSKQTIPILYIKLYMYQLFRSLAYIHSQACV 56
>15741
Length = 402
Score = 35.0 bits (79), Expect = 0.14, Method: Composition-based stats.
Identities = 14/44 (31%), Positives = 24/44 (54%)
Frame = -3
Query: 513 YLERNKNSLKVLTLVLYSLQICKAMAYLESINCVHRDIAVRNIL 556
+L N L ++L + + MA++ + VHRD+A RN+L
Sbjct: 133 FLTSTANDLTARDFFSFALHVARGMAHVANNKIVHRDVAARNVL 2
>01392
Length = 1806
Score = 34.7 bits (78), Expect = 0.19, Method: Compositional matrix adjust.
Identities = 34/129 (26%), Positives = 55/129 (42%), Gaps = 12/129 (9%)
Frame = -1
Query: 511 GHYLERNKNSLKVLTLVLYSLQICKAMAYLESINCVHRDIAVRNILVASPE---CVKLGD 567
GH ER + L I +A+ +L S HRD+ NIL + VK+ D
Sbjct: 1806 GHLCEREAS--------LVVRHIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICD 1651
Query: 568 FGLSRYIE-DEDYYKASVTRLPI---KWMSPESINFR-----RFTTASDVWMFAVCMWEI 618
F L+ I D D K P+ ++M+PE ++ + D+W + ++ I
Sbjct: 1650 FDLASGISCDGDGTKTPELLTPVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILY-I 1474
Query: 619 LSFGKQPFF 627
+ G PF+
Sbjct: 1473 MLCGYPPFY 1447
>38046
Length = 446
Score = 33.9 bits (76), Expect = 0.39, Method: Composition-based stats.
Identities = 16/32 (50%), Positives = 20/32 (62%)
Frame = -1
Query: 533 ICKAMAYLESINCVHRDIAVRNILVASPECVK 564
I AMAY+E N +HR++ RNILV VK
Sbjct: 98 IADAMAYMEKENFIHRNLGDRNILVGPNNRVK 3
>27287
Length = 514
Score = 33.5 bits (75), Expect = 0.44, Method: Compositional matrix adjust.
Identities = 14/34 (41%), Positives = 19/34 (55%)
Frame = -2
Query: 646 KPDLCPPVLYTLMTRCWDYDPSDRPRFTELVCSL 679
KP ++ +M CW DP+DRP F+ LV L
Sbjct: 507 KPPYASSEMFGIMHSCWQEDPNDRPSFSRLVQEL 406
>21433
Length = 590
Score = 31.6 bits (70), Expect = 1.5, Method: Composition-based stats.
Identities = 23/91 (25%), Positives = 38/91 (41%)
Frame = +2
Query: 529 YSLQICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVTRLP 588
Y Q+ A+ Y +HRDI N+L+ +K+ DFG S + T
Sbjct: 182 YIYQLSSALEYCHYRKVIHRDIKPENLLLGLKGDLKIADFGWSVHAPSSRRTTMCGT--- 352
Query: 589 IKWMSPESINFRRFTTASDVWMFAVCMWEIL 619
+ ++ PE + + D+W V +E L
Sbjct: 353 LDYLPPEMVEGKTHDENVDLWSLGVLCYEFL 445
>26560
Length = 398
Score = 31.6 bits (70), Expect = 1.7, Method: Composition-based stats.
Identities = 24/99 (24%), Positives = 44/99 (44%)
Frame = -1
Query: 528 LYSLQICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVTRL 587
Y+ ++ + ++ S V+RD+ NIL+ V++ D GL+ + + + T
Sbjct: 344 FYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGLACDFSKKRPHASVGTH- 168
Query: 588 PIKWMSPESINFRRFTTASDVWMFAVCMWEILSFGKQPF 626
+M+PE + + +S W CM L G PF
Sbjct: 167 --GYMAPEVLMKGQSYDSSADWFSFGCMLYKLLKGHSPF 57
>16708
Length = 1397
Score = 31.2 bits (69), Expect = 2.2, Method: Compositional matrix adjust.
Identities = 28/112 (25%), Positives = 46/112 (41%), Gaps = 7/112 (6%)
Frame = -1
Query: 500 IIMELYPYGELGHYLERNKN-------SLKVLTLVLYSLQICKAMAYLESINCVHRDIAV 552
I++ Y G L + KN S + + +C A+ ++ + VH D+
Sbjct: 1184 ILLHFYEMGPLCNVYAHYKNKEMPIRWSNPAMVCCIAGQXVC-ALEHIHELGVVHMDVKA 1008
Query: 553 RNILVASPECVKLGDFGLSRYIEDEDYYKASVTRLPIKWMSPESINFRRFTT 604
N+LV + KL D+G+++ YK V P + S N R F T
Sbjct: 1007 DNVLVDAHGNCKLTDYGIAQ------LYK--VYPAPTETHSSGCTNKRTFYT 876
>37602
Length = 804
Score = 30.0 bits (66), Expect = 4.8, Method: Compositional matrix adjust.
Identities = 15/34 (44%), Positives = 18/34 (52%)
Frame = -1
Query: 535 KAMAYLESINCVHRDIAVRNILVASPECVKLGDF 568
K + YL +HRDI NIL+ VKL DF
Sbjct: 186 KGLHYLHRRGKMHRDIKGANILLTEEGDVKLADF 85
>00302
Length = 927
Score = 30.0 bits (66), Expect = 5.4, Method: Composition-based stats.
Identities = 14/42 (33%), Positives = 24/42 (57%)
Frame = -2
Query: 537 MAYLESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDED 578
+ YL+S+ C+H+ + LVA+ VK F ++R + ED
Sbjct: 458 LVYLDSV-CIHKSVVYEKCLVATDISVKYRLFTIARLVAPED 336
>26009
Length = 886
Score = 29.3 bits (64), Expect = 7.7, Method: Compositional matrix adjust.
Identities = 11/30 (36%), Positives = 19/30 (63%)
Frame = +3
Query: 532 QICKAMAYLESINCVHRDIAVRNILVASPE 561
Q+ A+ ++ S VHRDI N+L+ +P+
Sbjct: 735 QLVSALDFMHSKQLVHRDIKPENVLILTPD 824
>02638
Length = 1490
Score = 29.3 bits (64), Expect = 8.6, Method: Compositional matrix adjust.
Identities = 24/92 (26%), Positives = 42/92 (45%), Gaps = 4/92 (4%)
Frame = +1
Query: 589 IKWMSPESINFRRFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEK----GDRL 644
I +M+PE + + A DVW M E+ + + P+ + + + ++ K D
Sbjct: 28 IAFMAPEVLRGESYGRACDVWSVGCVMIEMCTC-RPPWNSHDISNHLALIFKIASSVDPP 204
Query: 645 PKPDLCPPVLYTLMTRCWDYDPSDRPRFTELV 676
P P+ P + LM RC + D RP +L+
Sbjct: 205 PIPENMSPPVRDLMLRCLEQDSDFRPSAKDLL 300
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000342242 | hsapiens_gene_ensembl | Protein
tyrosine kinase 2 beta (EC 2.7.10.2) (Focal adhesion kinase 2) (FADK
2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK
beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion
focal tyrosine kinase) (RAFTK). [Source:Uniprot/SWISSPROT;Acc:Q14289]
(967 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
06405 201 8e-52
21808 179 6e-45
09007 166 3e-41
04852 162 8e-40
11780 94 6e-36
07291 127 2e-29
17300 120 3e-29
20640 126 5e-29
07940 116 3e-26
14116 113 4e-25
18996 111 1e-24
22005 90 1e-23
08294 106 4e-23
14477 88 2e-17
13305 86 1e-16
17637 85 2e-16
17253 83 4e-16
12721 77 3e-14
01718 77 4e-14
18921 72 1e-12
19301 69 1e-11
27546 66 9e-11
14420 65 1e-10
13066 60 4e-09
00300 59 7e-09
31885 59 8e-09
07833 58 1e-08
30755 56 9e-08
21079 55 2e-07
29581 54 4e-07
19094 53 5e-07
15910 52 9e-07
19761 52 1e-06
01707 51 2e-06
14126 50 5e-06
18484 50 6e-06
13212 49 7e-06
25550 49 9e-06
00715 49 1e-05
01756 48 2e-05
12672 46 6e-05
26711 45 1e-04
32264 45 1e-04
01060 44 2e-04
04591 44 3e-04
03240 43 6e-04
04138 42 0.001
35671 41 0.002
01966 41 0.003
07933 39 0.007
07836 39 0.015
28157 37 0.033
32359 37 0.050
15741 35 0.13
01392 35 0.16
38046 34 0.37
27287 33 0.40
21433 32 1.2
02638 32 1.4
26560 32 1.6
16708 31 1.9
37602 30 5.0
00302 30 5.5
26009 29 8.3
>06405
Length = 1965
Score = 201 bits (512), Expect = 8e-52, Method: Compositional matrix adjust.
Identities = 100/254 (39%), Positives = 153/254 (60%), Gaps = 5/254 (1%)
Frame = +1
Query: 454 VAVKTCKKDCTLDNKEKFMSEAVIMKNLDHPHIVKLIGIIEEEPT-WIIMELYPYGELGH 512
VAVKT K+D N F+ EA IMK + HP++V+L+G+ EP +I+ E P+G L
Sbjct: 343 VAVKTLKEDTMALND--FLEEAAIMKEMKHPNLVQLLGVCTREPPFYIVTEFMPHGNLLD 516
Query: 513 YLERNKNSLKVLTLVLY-SLQICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLS 571
YL + T ++Y + QI MAYLE+ N +HRD+A RN LVA VK+ DFGL+
Sbjct: 517 YLRSSTREENGPTALMYMATQIASGMAYLETKNFIHRDLAARNCLVADSNMVKVADFGLA 696
Query: 572 RYIEDEDYYKASVTRLPIKWMSPESINFRRFTTASDVWMFAVCMWEILSFGKQPFFWLEN 631
R ++D+ Y + PIKW +PE + F RF+T SD+W F V +WE+ ++G P+ +E
Sbjct: 697 RLMKDDTYTAHIGAKFPIKWTAPEGLAFNRFSTRSDIWAFGVLLWELATYGMSPYPGVEL 876
Query: 632 KDVIGVLEKGDRLPKPDLCPPVLYTLMTRCWDYDPSDRPRFTELVCSLSDVYQME---KD 688
+V +LE+G R+ +P P +Y LM +CW +DP DRP F E+ L ++++ ++
Sbjct: 877 TEVYHLLERGYRMERPPGTPADVYILMLKCWQWDPKDRPTFKEIHFLLENMFEKSSICEE 1056
Query: 689 IAMEQERNARYRTP 702
+ E E+N + + P
Sbjct: 1057VEKELEKNDKKQMP 1098
>21808
Length = 1011
Score = 179 bits (453), Expect = 6e-45, Method: Compositional matrix adjust.
Identities = 91/220 (41%), Positives = 135/220 (61%), Gaps = 1/220 (0%)
Frame = +1
Query: 454 VAVKTCKKDCTLDNKEKFMSEAVIMKNLDHPHIVKLIGI-IEEEPTWIIMELYPYGELGH 512
VA+KT K T+D K+ F++EA IMK L HP +++L + +++P +II EL G L
Sbjct: 28 VAIKTLKSG-TMDPKD-FLAEAQIMKKLRHPKLIQLYAVCTQDDPIFIITELMKNGSLLE 201
Query: 513 YLERNKNSLKVLTLVLYSLQICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSR 572
+L+ LK+ L+ QI MAYLES N +HRD+A RNILV+ VK+ DFGL+R
Sbjct: 202 FLQGKGRVLKLPALIDIGAQIACGMAYLESQNYIHRDLAARNILVSDNNTVKIADFGLAR 381
Query: 573 YIEDEDYYKASVTRLPIKWMSPESINFRRFTTASDVWMFAVCMWEILSFGKQPFFWLENK 632
I++++Y R PIKW +PE+ N+ RFT SDVW F + + E +++G+ P+ + N
Sbjct: 382 VIKEDEYEARVGARFPIKWTAPEAANYNRFTIKSDVWSFGILLTETVTYGRVPYPGMTNA 561
Query: 633 DVIGVLEKGDRLPKPDLCPPVLYTLMTRCWDYDPSDRPRF 672
+V+ +E G R+P P CP LY +M CW + +RP
Sbjct: 562 EVLHQVEHGYRMPCPPGCPKPLYDIMLECWRKEEMERPHL 681
>09007
Length = 1440
Score = 166 bits (421), Expect = 3e-41, Method: Compositional matrix adjust.
Identities = 99/307 (32%), Positives = 163/307 (53%), Gaps = 10/307 (3%)
Frame = -1
Query: 406 PDETLRRPGGPQYGIAREDVVLNRILXXXXXXXXXXXXXTNHKGEKINVAVKTCKKDCTL 465
P + RP + I+++ V L++ L T GEK+ VAVK KD
Sbjct: 930 PVSAVVRPARGKQLISKDCVALSKSLGQGHFGTVRQAIWTAESGEKVQVAVKCLSKDKIH 751
Query: 466 DNKEKFMSEAVIMKNLDHPHIVKLIGIIEEEPTWIIM--ELYPYGELGHYLER--NKNSL 521
+ ++F+ E IM+ LDH +IV++ G++ + I++ EL P L ++ +
Sbjct: 750 KDGQEFLKETAIMQMLDHENIVRVYGVVMDNGADIMLVTELAPMRSLLECVKEVSARVDF 571
Query: 522 KVLTLVLYSLQICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSRYI-EDEDYY 580
V L +S Q+C M+YLES VHRD+A RNIL+ S VK+ D G+S + ++YY
Sbjct: 570 SVPRLCDFSQQVCDGMSYLESKRLVHRDLAARNILLFSKSKVKISDVGVSGALGAGKEYY 391
Query: 581 KASVT---RLPIKWMSPESINFRRFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGV 637
++ T + + W +PES F++ASDVW F V +WE + G QP+ L + ++
Sbjct: 390 QSQQTIHLQNAVAWCAPESFRNLCFSSASDVWAFGVLLWEFFTHGFQPWAGLNGQQIMEA 211
Query: 638 LE--KGDRLPKPDLCPPVLYTLMTRCWDYDPSDRPRFTELVCSLSDVYQMEKDIAMEQER 695
++ + RL +PDLCP Y +M +CW+ +P RP F++L +L + + I ++ +
Sbjct: 210 VDAPQSQRLEQPDLCPKEYYAVMLKCWEQEPQRRPTFSQLFLTLPQI----RPIQVKAVK 43
Query: 696 NARYRTP 702
+A TP
Sbjct: 42 DAPSSTP 22
>04852
Length = 1462
Score = 162 bits (409), Expect = 8e-40, Method: Compositional matrix adjust.
Identities = 92/255 (36%), Positives = 135/255 (52%), Gaps = 31/255 (12%)
Frame = +1
Query: 453 NVAVKTCKKDCTLDNKEKFMSEAVIMKNL----DHPHIVKLIGI-IEEEPTWIIMELYPY 507
VAVK + T ++ F+ E +MK + H +IV +G + P W+I+E
Sbjct: 25 TVAVKMLRDIVTAVEEQDFVQELQVMKAVKKMGSHINIVNFLGCCTQGGPLWVIVEFAKN 204
Query: 508 GELGHYLERNKNSLKVL------------------------TLVLYSLQICKAMAYLESI 543
G L +LE ++ + L+ Y+ QI + M +L S
Sbjct: 205 GNLRDFLESCRDGINGYGKFVSPQDPGWYTKTPGGHVIRRKNLLSYAFQIARGMEFLASR 384
Query: 544 NCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKA-SVTRLPIKWMSPESINFRRF 602
C+HRD+A RN+LV +K+ DFGLSR DYYK S RLP+KWM+PE++ R+
Sbjct: 385 KCIHRDLAARNVLVTEEHVLKIADFGLSR---TGDYYKKRSGGRLPVKWMAPEALFDMRY 555
Query: 603 TTASDVWMFAVCMWEILSFGKQPFFWLENKDVIG-VLEKGDRLPKPDLCPPVLYTLMTRC 661
TT SDVW F V +WEI S G P+ + N+++ +L+ R+P+P+L LY +M RC
Sbjct: 556 TTKSDVWSFGVVLWEIFSLGGMPYASIPNEELYSKLLDDAYRMPRPELASGNLYAIMERC 735
Query: 662 WDYDPSDRPRFTELV 676
W PSDRP F++LV
Sbjct: 736 WLNRPSDRPEFSQLV 780
>11780
Length = 1713
Score = 94.0 bits (232), Expect(2) = 6e-36, Method: Compositional matrix adjust.
Identities = 53/146 (36%), Positives = 85/146 (58%), Gaps = 2/146 (1%)
Frame = +3
Query: 454 VAVKTCK-KDCTLDNKEKFMSEAVIMKNLDHPHIVKLIGIIEEEPTWIIMELYPYGELGH 512
VA+K K KD ++ F+ EA +M +L H ++V+LIG++ E +++ E G L
Sbjct: 675 VAIKQLKDKD---RGEQSFLQEASVMTSLRHDNLVRLIGVVLGETIFLVTEFMGKGNLVE 845
Query: 513 YL-ERNKNSLKVLTLVLYSLQICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLS 571
YL R ++ + + ++ C AM YLES VHRD+A RN+LV K+ DFGL+
Sbjct: 846 YLRSRGRSVITKKDQINFATDTCAAMEYLESKRLVHRDLAARNVLVHDDGKAKVSDFGLA 1025
Query: 572 RYIEDEDYYKASVTRLPIKWMSPESI 597
++ D+ + SV + PIKW +PE++
Sbjct: 1026KF---GDFSQTSV-KFPIKWTAPEAL 1091
Score = 76.6 bits (187), Expect(2) = 6e-36, Method: Compositional matrix adjust.
Identities = 31/81 (38%), Positives = 55/81 (67%)
Frame = +1
Query: 601 RFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTR 660
+FT+ SD+W F + +WEI SFG+ P+ + DV+ +E+G R+ P+ CPP +Y++M +
Sbjct: 1102 KFTSKSDMWSFGILLWEIYSFGRVPYPRIPLTDVVMHVERGYRMEAPEGCPPEIYSIMKQ 1281
Query: 661 CWDYDPSDRPRFTELVCSLSD 681
W+ DP++RP F ++ L++
Sbjct: 1282 AWELDPNERPTFKSVLARLNN 1344
>07291
Length = 833
Score = 127 bits (319), Expect = 2e-29, Method: Compositional matrix adjust.
Identities = 61/157 (38%), Positives = 95/157 (60%), Gaps = 2/157 (1%)
Frame = +1
Query: 521 LKVLTLVLYSLQICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYY 580
L V+ L+ + QI MAYL+ + VHR++A RN +V ++L D+G++ + + YY
Sbjct: 40 LTVVQLLDFGRQIADGMAYLQEVKVVHRNLAARNCIVTEDGRLQLSDYGVTGSLFPQSYY 219
Query: 581 KA--SVTRLPIKWMSPESINFRRFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVL 638
A S R +KWM+PE+I+ F++ SDVW F V +WE+L+ G P+ +EN ++ L
Sbjct: 220 TADDSPARDLVKWMAPETIDNFHFSSKSDVWAFGVVLWELLTRGITPYPDVENSSLLPYL 399
Query: 639 EKGDRLPKPDLCPPVLYTLMTRCWDYDPSDRPRFTEL 675
++G R+ KP P +Y +MT CW+ P RP F EL
Sbjct: 400 KEGHRMKKPKQSPEPVYEMMTACWNESPEQRPDFAEL 510
>17300
Length = 480
Score = 120 bits (302), Expect(2) = 3e-29, Method: Composition-based stats.
Identities = 55/116 (47%), Positives = 76/116 (65%), Gaps = 3/116 (2%)
Frame = +1
Query: 533 ICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSRYIED---EDYYKASVTRLPI 589
I M L + VHRD+A RNILV K+ DFGLSR IE E Y ++P+
Sbjct: 1 ISSGMGXLADMGYVHRDLAARNILVNEILVCKVADFGLSREIESDTTEGAYTTKGGKIPV 180
Query: 590 KWMSPESINFRRFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLP 645
+W +PE+I +R+FT+ASDVW F V MWE++S+G++P++ N+DVI +EKG RLP
Sbjct: 181 RWTAPEAIAYRKFTSASDVWSFGVVMWEVMSYGERPYWNWSNQDVIKAVEKGYRLP 348
Score = 26.9 bits (58), Expect(2) = 3e-29, Method: Compositional matrix adjust.
Identities = 11/35 (31%), Positives = 19/35 (54%)
Frame = +2
Query: 650 CPPVLYTLMTRCWDYDPSDRPRFTELVCSLSDVYQ 684
CP L+ LM W + S RP+ + +V +L + +
Sbjct: 359 CPEALHQLMLDAWQKERSHRPKMSMVVKTLDKLIR 463
>20640
Length = 1492
Score = 126 bits (316), Expect = 5e-29, Method: Compositional matrix adjust.
Identities = 58/140 (41%), Positives = 88/140 (62%), Gaps = 1/140 (0%)
Frame = +1
Query: 546 VHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKAS-VTRLPIKWMSPESINFRRFTT 604
VHRD+A RN LV VK+ DFGL+R + DYY+ S +PI+WM E+I + +F+T
Sbjct: 10 VHRDLATRNCLVGHDLVVKISDFGLARSVHSVDYYRGSEHDAIPIRWMPLEAILYNKFST 189
Query: 605 ASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTRCWDY 664
SDVW F V +WEI +F QP++ L +++V+ +++G L P+ PP +Y LM +CW
Sbjct: 190 QSDVWSFGVVLWEIFAFALQPYYGLTHEEVVRFVKEGKVLACPERTPPPMYELMKQCWHR 369
Query: 665 DPSDRPRFTELVCSLSDVYQ 684
P+ RP F L +L +++
Sbjct: 370 RPATRPSFHTLHKTLENMHS 429
>07940
Length = 1336
Score = 116 bits (291), Expect = 3e-26, Method: Compositional matrix adjust.
Identities = 51/113 (45%), Positives = 78/113 (69%), Gaps = 4/113 (3%)
Frame = -3
Query: 518 KNSLKVLT---LVLYSLQICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSRYI 574
++ LK+LT L+ Y+ Q+ + M YL S C+HRD+A RN+LVA +K+ DFGL+R +
Sbjct: 374 QDMLKMLTPKDLISYAYQVARGMEYLASKQCIHRDLAARNVLVAEEYVLKIADFGLTRNL 195
Query: 575 EDEDYY-KASVTRLPIKWMSPESINFRRFTTASDVWMFAVCMWEILSFGKQPF 626
+ DYY K + RLP+KWM+PE++ R++T+ SDVW + V +WEI + G P+
Sbjct: 194 QQFDYYRKTTDGRLPVKWMAPEALFDRKYTSKSDVWSYGVLLWEIFTLGGNPY 36
>14116
Length = 1017
Score = 113 bits (283), Expect = 4e-25, Method: Compositional matrix adjust.
Identities = 61/185 (32%), Positives = 110/185 (59%), Gaps = 6/185 (3%)
Frame = -1
Query: 448 KGEKINVAVKTCKKDCTLDNK-EKFMSEAVIMKNLDHPHIVKLIGI---IEEEPTWIIME 503
KG+ I VAVKT + + + + F+ EA+IMK+ H +++ LIGI +++ P +++
Sbjct: 555 KGD-ILVAVKTLHNNNPREIELQSFLQEALIMKDFHHSNVLTLIGICLNLDDMPL-VVLP 382
Query: 504 LYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYLESINCVHRDIAVRNILVASPECV 563
+G+L Y+ +++ + L++Y + I + M YL + VHRD+A RN ++ V
Sbjct: 381 FMKHGDLLTYIRDDQHQPTIKDLIMYGVDIARGMDYLAGLKFVHRDLAARNCMLDEDFHV 202
Query: 564 KLGDFGLSRYIEDEDYYKA--SVTRLPIKWMSPESINFRRFTTASDVWMFAVCMWEILSF 621
K+ DFGL+R I +++YY + +LP+KWM+ ES+ + + +DVW + V +WE+L+
Sbjct: 201 KVADFGLARDIYEKEYYSSENKKAKLPVKWMALESLEKGNYDSKTDVWSYGVVLWELLTR 22
Query: 622 GKQPF 626
G
Sbjct: 21 GSDAL 7
>18996
Length = 491
Score = 111 bits (278), Expect = 1e-24, Method: Compositional matrix adjust.
Identities = 57/137 (41%), Positives = 84/137 (61%), Gaps = 6/137 (4%)
Frame = +2
Query: 546 VHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVTR-LPIKWMSPESINFRRFTT 604
+HRD+A RNILV CVK+ DFGL+++ + YY R +PIKW SPE+I +F++
Sbjct: 2 IHRDLAARNILVDR-SCVKISDFGLAQFANADGYYYGISQRDIPIKWYSPEAIETCKFSS 178
Query: 605 ASDVWMFAVCMWEILSFGKQPFFW----LENKDVIGVLEKGDRLPKPDLCPPVLYT-LMT 659
SDVW + V ++E+ S G+ P L ++ + L KG+RLPKP+LC +Y+ LM
Sbjct: 179 YSDVWSYGVTLFEMFSRGEIPNLLPGHDLTQEEFLNRLRKGERLPKPELCSDFVYSELMR 358
Query: 660 RCWDYDPSDRPRFTELV 676
CW P RP F +++
Sbjct: 359 PCWHEMPKSRPTFHQII 409
>22005
Length = 873
Score = 89.7 bits (221), Expect(2) = 1e-23, Method: Compositional matrix adjust.
Identities = 64/208 (30%), Positives = 96/208 (46%), Gaps = 45/208 (21%)
Frame = +1
Query: 457 KTCKKDCTLDNKEKFMSEAVIMKNLDHPHIVKLIGIIE-EEPTWIIMELYPYGELGHYL- 514
K K+D + D + F EA +M + DHP+IVKL+G+ +P ++ E G+L +L
Sbjct: 109 KMLKEDASEDLQSDFEREASLMADFDHPNIVKLLGVCAIGKPMCLLFEFMSKGDLNDFLR 288
Query: 515 -----------------------------------------ERNKNSLKVLTLVLY-SLQ 532
+R+ + + LY S Q
Sbjct: 289 LCSPENYNLPVSRSQNLVVDLEDGLRVEVEAEECEKDTQSEDRDCSGMLXTKDQLYISQQ 468
Query: 533 ICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKAS-VTRLPIKW 591
I MAYL + VHRD+A R + + + DFGL+R + DYY+ S +PI+W
Sbjct: 469 ISAGMAYLAQKDYVHRDLATRTVXSRTT*-S*ISDFGLARSVHSVDYYRGSEQDAIPIRW 645
Query: 592 MSPESINFRRFTTASDVWMFAVCMWEIL 619
M E+I + +F+T SDVW F V +WEIL
Sbjct: 646 MPLEAILYSKFSTQSDVWSFGVVLWEIL 729
Score = 39.3 bits (90), Expect(2) = 1e-23, Method: Compositional matrix adjust.
Identities = 15/49 (30%), Positives = 28/49 (57%)
Frame = +3
Query: 619 LSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTRCWDYDPS 667
+F QP++ L +++V+ ++ G L +P P +Y LM +CW P+
Sbjct: 726 FAFALQPYYGLTHEEVVNYVKAGKILEQPTKTPHQVYELMKQCWQRRPA 872
>08294
Length = 1849
Score = 106 bits (265), Expect = 4e-23, Method: Compositional matrix adjust.
Identities = 68/210 (32%), Positives = 104/210 (49%), Gaps = 13/210 (6%)
Frame = +2
Query: 484 PHIVKLIGIIEE-EPTWIIMELYPYGELGHYL--ERNKNS----LKVLTLVL-----YSL 531
P+IV +G+ E EP ++I E +G+L +L RN N +V L L
Sbjct: 887 PNIVHFMGVCREAEPHFLITEYCDWGDLKQFLLATRNDNGRGRGTRVPALALSQKLGMGQ 1066
Query: 532 QICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVTRLPIKW 591
Q+ M L + VH D+A RN+L+ S +K+ LS + +YY +P++W
Sbjct: 1067 QVAAGMEALSNQGLVHGDLAARNVLLTSRMQLKVARPALSGDVYASEYYPLHQRLVPLRW 1246
Query: 592 MSPESINFRRFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGD-RLPKPDLC 650
+ PE + TT DVW F V +WE+L P+ + +++V+ L+ L PD
Sbjct: 1247 LPPEGVLEDSATTCGDVWAFGVFLWEVLQLADLPYRLMSDEEVLRSLQHSQAALDSPD-A 1423
Query: 651 PPVLYTLMTRCWDYDPSDRPRFTELVCSLS 680
PP L +L+ RC PS RP F+E+ LS
Sbjct: 1424 PPALLSLLQRCTAQQPSQRPPFSEICSVLS 1513
>14477
Length = 493
Score = 88.2 bits (217), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 51/134 (38%), Positives = 79/134 (58%), Gaps = 2/134 (1%)
Frame = -1
Query: 451 KINVAVKTCKK-DCTLDNKEKFMSEAVIMKNLDHPHIVKLIGIIEEEPTWIIMELYPYGE 509
+I VA+K K D + + + EA +MK +DH HIV+LIG+ E E +++EL G
Sbjct: 409 EIPVAIKVLKNADLDPSVQSELIKEAEVMKKMDHMHIVRLIGLCEGETMMLVLELAKLGP 230
Query: 510 LGHYLERNKNSLKVLTLVLYSLQICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFG 569
L +L +NK+ L + ++ Q+ + M YLE+ VHRD+A RNIL+ K+ DFG
Sbjct: 229 LNKFLPKNKH-LPLWNILELMWQVSQGMEYLEANKFVHRDLAARNILLCDEHFAKISDFG 53
Query: 570 LSRYIEDE-DYYKA 582
+S+ + E +YY A
Sbjct: 52 MSKTLSRENNYYMA 11
>13305
Length = 549
Score = 85.5 bits (210), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 42/113 (37%), Positives = 64/113 (56%), Gaps = 3/113 (2%)
Frame = +2
Query: 585 TRLPIKWMSPESINFRRFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRL 644
TR+PI+WM+ ES+ +TT SDVW F V +WEI + G P+ + + + L+ G RL
Sbjct: 5 TRVPIRWMAVESLFNNTYTTQSDVWSFGVVLWEIFTLGGTPYSSTDTQQLFAFLKDGYRL 184
Query: 645 PKPDLCPPVLYTLMTRCWDYDPSDRPRFTELVCSLS---DVYQMEKDIAMEQE 694
+P LC Y +M +CW+ + RP F EL L D Q+ +++ E+E
Sbjct: 185 KRPKLCDQNTYAMMLQCWNENAQRRPTFPELCGRLQRMLDDCQVYMNLSTEEE 343
>17637
Length = 447
Score = 84.7 bits (208), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 46/122 (37%), Positives = 68/122 (55%), Gaps = 1/122 (0%)
Frame = +1
Query: 563 VKLGDFGLSRYIEDEDYYKASVTRL-PIKWMSPESINFRRFTTASDVWMFAVCMWEILSF 621
VKL D LSR + DY PIKW+S E++ + SDVW F V MWE+ +
Sbjct: 28 VKLTDSALSRDLFSGDYNCLGDGEYRPIKWLSLEALQKSHYNEGSDVWSFGVLMWEMCTL 207
Query: 622 GKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTRCWDYDPSDRPRFTELVCSLSD 681
GK P+ ++ ++ L+ G RL +P CP L+T+M CW P++RP F++L LS+
Sbjct: 208 GKLPYAEIDPYEMEHYLKDGYRLAQPFNCPDELFTIMAYCWASMPAERPSFSQLQICLSE 387
Query: 682 VY 683
+
Sbjct: 388 FH 393
>17253
Length = 483
Score = 83.2 bits (204), Expect = 4e-16, Method: Composition-based stats.
Identities = 50/160 (31%), Positives = 83/160 (51%), Gaps = 15/160 (9%)
Frame = -1
Query: 447 HKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKNLD-HPHIVKLIGIIE-EEPTWIIMEL 504
H + VAVKT + T K +F+ E IM+ L HP++V +G +P I+ME
Sbjct: 480 HARQWDTVAVKTHNEAATDAEKSEFLRELSIMRKLPRHPNVVSFMGCCTMSDPALILMEF 301
Query: 505 YPYGELGHYLERNK-----------NSLKVLTLVLYSLQICKAMAYLESINCVHRDIAVR 553
+G+L +L + + N L ++L + + MA++ + VHRD+A R
Sbjct: 300 CCHGDLLSFLRKRRPDRTVFLTSTANDLTARDFFSFALHVARGMAHVANNKIVHRDVAAR 121
Query: 554 NILVASPECVKLGDFGLSRYIEDEDYYKASVTR--LPIKW 591
N+L++ K+ DFGLSR + D++ V+R LP++W
Sbjct: 120 NVLISERNVCKVSDFGLSRRVGDQNDVYEIVSRRPLPLRW 1
>12721
Length = 821
Score = 77.4 bits (189), Expect = 3e-14, Method: Compositional matrix adjust.
Identities = 56/210 (26%), Positives = 102/210 (48%), Gaps = 8/210 (3%)
Frame = +1
Query: 468 KEKFMSEAVIMKNLDHPHIVKLIG--IIEEEPTWIIMELYPYGELGHYLERNK-NSLKVL 524
+E +E V+M++ HP+IV++ ++ +E W++ME G L + N+ + +++
Sbjct: 208 RELLFNEVVVMRDYHHPNIVEMYNSYLVNDE-LWVVMEFMEGGALTDIVTNNRMDEVQIA 384
Query: 525 TLVLYSLQICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASV 584
T+ L KA+A+L + +HRDI +IL++ VKL DFG + + + S+
Sbjct: 385 TVCRACL---KALAFLHANGVIHRDIKSDSILLSHDGKVKLXDFGFCAQVTQDLQKRKSL 555
Query: 585 TRLPIKWMSPESINFRRFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRL 644
P WM+PE I+ + D+W + + E++ + PFF N+ + + + +
Sbjct: 556 VGTPY-WMAPEVISRLPYGPEVDIWSLGIMVMEMID-AEPPFF---NEPPLQAMRRIRDM 720
Query: 645 PKPDL-----CPPVLYTLMTRCWDYDPSDR 669
P P L P L + R DP R
Sbjct: 721 PPPKLRNTHKISPRLQGFIDRMLVRDPHQR 810
>01718
Length = 959
Score = 77.0 bits (188), Expect = 4e-14, Method: Compositional matrix adjust.
Identities = 62/255 (24%), Positives = 110/255 (43%), Gaps = 10/255 (3%)
Frame = +3
Query: 450 EKINVAVKTCKKDCTLDNKEKFMSEAVIMKNLDHPHIVKLIGI-IEEEPTWIIMELYPYG 508
+I V K + N+ + E ++ L H +I++ +G+ + E + E P G
Sbjct: 210 HRITGQVMALKMNTMTSNRHNMLREVQLLNRLQHANILRFMGVCVHEGQLHALTEYIPSG 389
Query: 509 ELGHYLERNKNSLKVLTLVLYSLQICKAMAYLESINCVHRDIAVRNILVASPEC----VK 564
L LE+ L + +L + + + YL S +HRD+ +NIL+ +
Sbjct: 390 NLEQLLEKKDEELPWTQRIQLTLGLARGLDYLHSTRFIHRDLTSKNILIRREDNHGYHAV 569
Query: 565 LGDFGLSRYIEDE-DYYKASVTRLPIKWMSPESINFRRFTTASDVWMFAVCMWEILSFGK 623
+ DFGL+ I D D K P WM+PE +N + +D++ + M EI +
Sbjct: 570 IADFGLATKIPDPLDKEKLPTVGSPY-WMAPEVLNGHFYNERADLFSVGIIMCEITARIP 746
Query: 624 QPFFWLENKDVIGVLEKGDRLPKPDL---CPPVLYTLMTRCWDYDPSDRPRFTELVCSLS 680
+ + GV D + ++ CP L +C DP RPR E++ L
Sbjct: 747 ADPDIMPRMNNFGV----DYVALSEMISYCPLDYLQLAFKCCQVDPQKRPRGVEIIEWLE 914
Query: 681 DVYQ-MEKDIAMEQE 694
+++ ++ DI Q+
Sbjct: 915 KIFKNLKNDIFTRQQ 959
>18921
Length = 697
Score = 72.0 bits (175), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 55/183 (30%), Positives = 88/183 (48%), Gaps = 4/183 (2%)
Frame = +2
Query: 447 HKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKNLDHPHIVKLIG-IIEEEPTWIIMELY 505
HK +A+K D L ++ + E IM+ D +IVK G + WI+ME
Sbjct: 92 HKETGQVLAIKQVPVDTDL---QEIIKEISIMQQCDSKYIVKYYGSYFKNTDLWIVMEYC 262
Query: 506 PYGELGHYLE-RNKNSLK--VLTLVLYSLQICKAMAYLESINCVHRDIAVRNILVASPEC 562
G + + RNK ++ + T++ Y+L K + YL S +HRDI NIL+ +
Sbjct: 263 GAGSVSDIMRLRNKTLVEREIATILYYTL---KGLXYLHSRRKIHRDIKAGNILLNNEGH 433
Query: 563 VKLGDFGLSRYIEDEDYYKASVTRLPIKWMSPESINFRRFTTASDVWMFAVCMWEILSFG 622
KL DFG++ + D + +V P WM+PE I + +D+W + E ++ G
Sbjct: 434 AKLADFGVAGQLTDTMAKRNTVIGTPY-WMAPEVIQEIGYDCVADIWSLGITALE-MAEG 607
Query: 623 KQP 625
K P
Sbjct: 608 KPP 616
>19301
Length = 712
Score = 68.6 bits (166), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 38/95 (40%), Positives = 53/95 (55%), Gaps = 1/95 (1%)
Frame = +2
Query: 478 MKNLDHPHIVKLIGIIEEEPTW-IIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKA 536
++ L+HP+I+ G+ + P + IIME PYG+L L K L L +S QI
Sbjct: 431 LRKLNHPNIISFKGVCTQAPCYCIIMEYCPYGQLYEVLRDGKEIPPALVLD-WSKQIASG 607
Query: 537 MAYLESINCVHRDIAVRNILVASPECVKLGDFGLS 571
M YL S +HRD+ N+LVA + VK+ DFG S
Sbjct: 608 MNYLHSHKIIHRDLKSPNVLVAKNDVVKISDFGTS 712
>27546
Length = 426
Score = 65.9 bits (159), Expect = 9e-11, Method: Composition-based stats.
Identities = 42/134 (31%), Positives = 71/134 (52%), Gaps = 3/134 (2%)
Frame = -1
Query: 446 NHKGEKINVAVKTCKK-DCTLDNKEKFM-SEAVIMKNLDHPHIVKLIGIIEEEPT-WIIM 502
+ G +N+A K K +D +KF E I+ LDHP+I+++ I++ P +I M
Sbjct: 420 DESGHGVNLACKIIDKAKAPIDFVKKFFPRELEILTRLDHPNIIQIHSILQRGPKIFIFM 241
Query: 503 ELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYLESINCVHRDIAVRNILVASPEC 562
G++ ++++ + T V + Q+ KA+ YL S + HRD+ NIL++
Sbjct: 240 RYAEKGDMLSHIKKTGPIDEAQTKVWF-FQMAKALQYLHSHDIAHRDLKCENILLSKRLN 64
Query: 563 VKLGDFGLSRYIED 576
VK+ DFG +RY D
Sbjct: 63 VKIADFGFARYCRD 22
>14420
Length = 528
Score = 65.5 bits (158), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 44/162 (27%), Positives = 78/162 (48%), Gaps = 2/162 (1%)
Frame = +2
Query: 468 KEKFMSEAVIMKNLDHPHIVK-LIGIIEEEPTWIIMELYPYGELGHYL-ERNKNSLKVLT 525
KE ++E ++M+ +P+IV L + E W++ME G L + E + ++
Sbjct: 32 KELIINEILVMRENQNPNIVNYLDSYLVGEELWVVMEFLAGGSLTDVVTETCMDEGQIAA 211
Query: 526 LVLYSLQICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVT 585
+ LQ A+ +L +HRDI NIL+ VKL DFG + E ++++
Sbjct: 212 VCRECLQ---ALEFLHENQVIHRDIKSDNILLGMDGSVKLTDFGFCAQLSPEQSKRSTMV 382
Query: 586 RLPIKWMSPESINFRRFTTASDVWMFAVCMWEILSFGKQPFF 627
P WM+PE + +++ D+W V E++ G+ P+
Sbjct: 383 GTP-YWMAPEVVTRKQYGPTVDIWSLGVMCIEMIE-GEPPYL 502
>13066
Length = 551
Score = 60.1 bits (144), Expect = 4e-09, Method: Compositional matrix adjust.
Identities = 41/126 (32%), Positives = 66/126 (52%), Gaps = 3/126 (2%)
Frame = +3
Query: 449 GEKINVAVKTCKKD-CTLDNKEKFM-SEAVIMKNLDHPHIVKLIGIIEEEP-TWIIMELY 505
G I +A K K+ +D EKF E ++ LDHP+I+++ I++ P +I M
Sbjct: 45 GRNIKLACKIIDKEKAPVDFVEKFFPRELDLLTKLDHPYIIQIHSILQRXPKNFIFMRFA 224
Query: 506 PYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYLESINCVHRDIAVRNILVASPECVKL 565
G+L Y++ +K ++ Q+ A+ YL S + HRD+ NIL++S VKL
Sbjct: 225 ERGDLLTYIQE-VGFVKEKQAKIWFYQMTTALNYLHSYDVAHRDLKCENILLSSHFNVKL 401
Query: 566 GDFGLS 571
DFG +
Sbjct: 402 ADFGFA 419
>00300
Length = 2318
Score = 59.3 bits (142), Expect = 7e-09, Method: Compositional matrix adjust.
Identities = 55/218 (25%), Positives = 97/218 (44%), Gaps = 8/218 (3%)
Frame = -1
Query: 474 EAVIMKNLDHPHIVKLIGI-IEEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQ 532
E I + + H ++VK G+ + ++ + ME Y + G E K L + Y+ +
Sbjct: 1511 EIKIFEGIQHENLVKYYGVEVHKDEMLMFME---YCDTGTIEEAAKMGLPEYLIRRYTRE 1341
Query: 533 ICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVTRL--PIK 590
I A+ +L + VHRDI NI + S VKLGDFG S ++ L
Sbjct: 1340 IVLAVNHLHENSIVHRDIKGANIFLTSNGHVKLGDFGCSVKLKSHTTMPGEFHNLVGTTA 1161
Query: 591 WMSPESINFR---RFTTASDVWMFAVCMWEILSFGKQPFFWLENK-DVIGVLEKGDRLPK 646
+M+PE + A+D+W + E ++ GK+P+ L+N ++ + G +
Sbjct: 1160 YMAPEVFTQNDQGGYGRAADIWSLGCVVIE-MATGKRPWHDLDNNYQIMYKVGIGHKPAV 984
Query: 647 PDLCPPVLYTLMTRCWDYDPSDRPRFTELV-CSLSDVY 683
PD + +DP+ R ++L+ + + VY
Sbjct: 983 PDSLSVEGKHFLDLIMCHDPAQRALASQLLDHTFTKVY 870
>31885
Length = 529
Score = 59.3 bits (142), Expect = 8e-09, Method: Compositional matrix adjust.
Identities = 44/156 (28%), Positives = 83/156 (53%), Gaps = 6/156 (3%)
Frame = -2
Query: 477 IMKNLDHPHIVKL-IGIIEEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICK 535
++ LDHP +V L +EE +++++L+ G+L +++++ + S + + Y Q+
Sbjct: 513 MLTRLDHPFLVNLWYAFQDEEDLFMVVDLFLGGDLRYHMQQ-EVSFREDCVKFYLCQLAL 337
Query: 536 AMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVTRLPIKWMSPE 595
+ YL S VHRDI NIL+ + DF ++ +ED++ ++ P +M+PE
Sbjct: 336 VLDYLRSQKIVHRDIKPDNILLDEQGHCHVTDFNIATQLEDDELATSTSGTRP--YMAPE 163
Query: 596 ----SINFRR-FTTASDVWMFAVCMWEILSFGKQPF 626
+IN RR + D W V ++E+L ++PF
Sbjct: 162 VYGVAINERRGYGFPVDWWSLGVSLFELLK-KRRPF 58
>07833
Length = 1504
Score = 58.2 bits (139), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 52/221 (23%), Positives = 101/221 (45%), Gaps = 15/221 (6%)
Frame = -3
Query: 471 FMSEAVIMKNLDHPHIVKLIGIIEEEPTWIIM-ELYPYGELGHYLERNKNSLKVLTLVL- 528
FM E ++ +HP+++ ++ + P +++ + P+G L + L + L
Sbjct: 1478 FMEEFPRLRIFNHPNVLPVLACCNQPPNLVLISQFMPFGSLYNTLHGESGIVVDQNQSLR 1299
Query: 529 YSLQICKAMAYLESINCVHRDIAVRNILVASPEC---------VKLGDFGLSRYIEDEDY 579
+++ I + M +L S+ + + N L+ S + + D+ S + + + Y
Sbjct: 1298 FAMDIARGMEFLHSM-----EPTIPNFLLTSKHVMIDEDLTARINMADYCFSFHEKGKVY 1134
Query: 580 YKASVTRLPIKWMSPESINFRR---FTTASDVWMFAVCMWEILSFGKQPFFWLENKDV-I 635
A WM+PE++ R T A+D+W FA+ MWE L + PF L + +V +
Sbjct: 1133 SPA--------WMAPEALQRRPDDINTRAADMWSFAILMWE-LETREVPFAELSSMEVGM 981
Query: 636 GVLEKGDRLPKPDLCPPVLYTLMTRCWDYDPSDRPRFTELV 676
V +G R+ P + L+ C + +P RPRF ++
Sbjct: 980 KVALEGLRISIPPGISLHMSRLIKICMNEEPGKRPRFDMII 858
>30755
Length = 1137
Score = 55.8 bits (133), Expect = 9e-08, Method: Compositional matrix adjust.
Identities = 30/101 (29%), Positives = 55/101 (54%), Gaps = 1/101 (0%)
Frame = +2
Query: 528 LYSLQICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVTRL 587
Y +I A+ YL S ++RD+ + N+L+ +K+ DFGL + ED Y + + T
Sbjct: 44 FYGAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCK--EDITYGRTTKTFC 217
Query: 588 PI-KWMSPESINFRRFTTASDVWMFAVCMWEILSFGKQPFF 627
++++PE ++ + A D W V M+E++ G+ PF+
Sbjct: 218 GTPEYLAPEVLDDNDYGRAVDWWGTGVVMYEMIC-GRLPFY 337
>21079
Length = 878
Score = 54.7 bits (130), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 40/146 (27%), Positives = 69/146 (47%), Gaps = 3/146 (2%)
Frame = +1
Query: 483 HPHIVKLIGIIEEEPTWI-IMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYLE 541
HP ++ L E T + +ME GEL + R+ L V + QIC + Y+
Sbjct: 1 HPKLLMLWDAFEAPRTMVLVMEFVGAGELFERVIRDDFVLTERDCVHFVRQICSGVGYMH 180
Query: 542 SINCVHRDIAVRNILVASPEC--VKLGDFGLSRYIEDEDYYKASVTRLPIKWMSPESINF 599
+ + +H D+ N+L S +K+ DFGL+R+ + D V ++++PE +N+
Sbjct: 181 TQSILHLDLKPENVLCVSDNSNQIKIIDFGLARFYKPGD--SLQVLFGTPEFIAPEVVNY 354
Query: 600 RRFTTASDVWMFAVCMWEILSFGKQP 625
+D+W V + +LS G P
Sbjct: 355 DEINFTTDMWSIGVICYILLS-GLSP 429
>29581
Length = 1278
Score = 53.5 bits (127), Expect = 4e-07, Method: Compositional matrix adjust.
Identities = 43/158 (27%), Positives = 73/158 (46%), Gaps = 6/158 (3%)
Frame = -2
Query: 475 AVIMKNLDHPHIVKLIGII---EEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSL 531
+ + NL H +IV+L ++ + +++ME Y +L L+ + L
Sbjct: 1202 STFLLNLRHQNIVQLQEVVVGKSLDSLFLVME-YCEQDLASLLDNMPAPFSESQVKCIVL 1026
Query: 532 QICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSR-YIEDEDYYKASVTRLPIK 590
Q+ K + YL +HRD+ V N+L+ CVK+ DFGL+R Y + + V L
Sbjct: 1025 QLLKGLRYLHEAFIIHRDLKVSNLLMTDKGCVKIADFGLARNYGKPQKPMTPKVVTL--- 855
Query: 591 WMSPESINF--RRFTTASDVWMFAVCMWEILSFGKQPF 626
W + F + +TA D+W + E+L G +P
Sbjct: 854 WYRAPELLFGSKTHSTAIDMWSAGCILGELL--GHKPL 747
>19094
Length = 898
Score = 53.1 bits (126), Expect = 5e-07, Method: Composition-based stats.
Identities = 33/105 (31%), Positives = 54/105 (51%), Gaps = 2/105 (1%)
Frame = +1
Query: 516 RNKNSLK--VLTLVLYSLQICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSRY 573
RNK ++ + T++ Y+L K + YL S +HRDI NIL+ + KL DFG++
Sbjct: 37 RNKTLVEREIATILYYTL---KGL*YLHSRRKIHRDIKAGNILLNNEGHAKLADFGVAGQ 207
Query: 574 IEDEDYYKASVTRLPIKWMSPESINFRRFTTASDVWMFAVCMWEI 618
+ D + +V P WM+PE I + +D+W + E+
Sbjct: 208 LTDTMAKRNTVIGTPY-WMAPEVIQEIGYDCVADIWSLGITALEM 339
>15910
Length = 1361
Score = 52.4 bits (124), Expect = 9e-07, Method: Compositional matrix adjust.
Identities = 40/123 (32%), Positives = 64/123 (52%), Gaps = 6/123 (4%)
Frame = +2
Query: 511 GHYLERNKNSLKVLTLVLYSLQICKAMAYLESINCVHRDIAVRNILVASPEC------VK 564
G Y E K++ + ++ +L+ +Q Y+ + VHRD+ N+L EC +K
Sbjct: 449 GQYTE--KDAARAISDILHGVQ------YIHANGVVHRDLKPENLLY---ECMTDDSKLK 595
Query: 565 LGDFGLSRYIEDEDYYKASVTRLPIKWMSPESINFRRFTTASDVWMFAVCMWEILSFGKQ 624
L DFGLSR IE E ++V P + +PE + ++T + D+W V + IL G +
Sbjct: 596 LADFGLSRIIEPE-VQMSTVCGTP-GYCAPEVLKGDKYTPSVDMWSVGVIAY-ILLCGYE 766
Query: 625 PFF 627
PFF
Sbjct: 767 PFF 775
>19761
Length = 473
Score = 51.6 bits (122), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 38/132 (28%), Positives = 65/132 (49%), Gaps = 9/132 (6%)
Frame = -3
Query: 526 LVLYSLQICKAMAYLESINCV--HRDIAVRNILVASPECVKLGDFGLSRYIED-EDYYKA 582
+V + +Q A+ Y+ + V HRD+ +NI V V+LGD GL+R + D+ +
Sbjct: 417 IVCWLMQTASALNYMHTHTPVILHRDLKPQNIYVTEKGDVRLGDLGLARKLTGPADFATS 238
Query: 583 SVTRLPIKWMSPESINFRRFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVL---- 638
V I ++SPE ++ + + + SD+W ++I GK+ D +GV+
Sbjct: 237 QVGT--IMYLSPEILSQQPYNSKSDIWSLGCVFYDIT--GKK------GSDEMGVMFLLV 88
Query: 639 --EKGDRLPKPD 648
G +LP PD
Sbjct: 87 QVMGGRKLPLPD 52
>01707
Length = 757
Score = 51.2 bits (121), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 47/184 (25%), Positives = 84/184 (45%), Gaps = 5/184 (2%)
Frame = +1
Query: 468 KEKFMSEAVIMKNLDHPHIVKLIGIIEEEPTWIIMELYPYGELGHYLERNKNSLKVLTLV 527
K+ M E ++K L HP++V+LI + + ++ Y L + L+R L +
Sbjct: 193 KKIAMREIRMLKQLKHPNLVRLIEVFRRKKRLHLVFDYVDHTLLNELDRYPRGLPEPMVK 372
Query: 528 LYSLQICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSRYIE--DEDYYKASVT 585
Q A+ + N +HRD+ NIL+ VKL DFG +R + ++Y T
Sbjct: 373 RIIYQTLLAVNFCHQYNTIHRDVKPENILITRQGQVKLCDFGFARILTGPGDEYTDYVAT 552
Query: 586 RLPIKWMSPE-SINFRRFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEK--GD 642
R + +PE + ++ DVW E+L+ G+ + + D + ++ K GD
Sbjct: 553 RW---YRAPELLVGDTQYGPPVDVWAIGCVFAELLT-GQALWPGRSDVDQLHLIRKTLGD 720
Query: 643 RLPK 646
+P+
Sbjct: 721 LIPR 732
>14126
Length = 1265
Score = 49.7 bits (117), Expect = 5e-06, Method: Compositional matrix adjust.
Identities = 55/208 (26%), Positives = 93/208 (44%), Gaps = 26/208 (12%)
Frame = +3
Query: 461 KDCTLDNKEKFM-----SEAVIMKNLD---HPHIVKLIG-----IIEEEPTWIIMELYPY 507
K L+N E+ M E ++K L+ HP++V+L+ I + E ++ Y
Sbjct: 285 KRIRLNNTEEGMPMMAIREISMLKQLEQYEHPNVVRLLDVSHNTITDREIRLNLVFEYIE 464
Query: 508 GELGHYLER------NKNSLKVLTLVLYSLQICKAMAYLESINCVHRDIAVRNILVASPE 561
+L YL + + +K L L Q+ + +L S VHRD+ +N+L++
Sbjct: 465 HDLATYLAKCPSPGLGPDRIKDLML-----QLLNGVDFLHSNRIVHRDLKPQNLLISKDG 629
Query: 562 CVKLGDFGLSRYIEDEDYYKASVTRLPIKWM-SPESINFRRFTTASDVWMFAVCMWEILS 620
+KL DFGL+R ++ A T + W SPE + + T+ D+W E+ +
Sbjct: 630 RLKLADFGLARIYS---FHMALTTVVVTLWYRSPEVLMQAEYGTSVDIWSCGCIFAELFT 800
Query: 621 F-----GKQPFFWLENK-DVIGVLEKGD 642
G F L+ +VIG+ GD
Sbjct: 801 RRALFKGSSEFDQLKKIFEVIGLPPAGD 884
>18484
Length = 635
Score = 49.7 bits (117), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 25/114 (21%), Positives = 58/114 (50%)
Frame = +1
Query: 513 YLERNKNSLKVLTLVLYSLQICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSR 572
Y + + K Y+ +I + +L ++RD+ + N+++ S +K+ DFG+ +
Sbjct: 10 YRIQQEGKFKEPVAAFYAAEIAVGLFFLHDQGIIYRDLKLDNVMLDSEGHIKIADFGMCK 189
Query: 573 YIEDEDYYKASVTRLPIKWMSPESINFRRFTTASDVWMFAVCMWEILSFGKQPF 626
D + P +++PE + ++ ++ + D W + V ++E+L+ G+ PF
Sbjct: 190 EGMTGDATTRTFCGTP-DYIAPEIVLYQPYSKSVDWWAYGVLLFEMLA-GQPPF 345
>13212
Length = 1067
Score = 49.3 bits (116), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 43/188 (22%), Positives = 79/188 (42%), Gaps = 10/188 (5%)
Frame = -1
Query: 499 WIIMELYP---YGELGHYLERNKNSLKVLTLVLYSLQICKAMAYLESINCVHRDIAVRNI 555
W I++++ +G L + + + + ++C A+ +L + +HRDI N+
Sbjct: 1064 WXIVDVFRVLWWGALDSIMVDLEKPMTEAQICYVCHEMCMALDFLHRHHVIHRDIKAGNV 885
Query: 556 LVASPECVKLGDFGLSRYIEDEDYYKASVTRLPIKWMSP-----ESINFRRFTTASDVWM 610
L+ VKL DFG+S + + P WM+P E++ + +D+W
Sbjct: 884 LLTIDGEVKLADFGVSAKNTQTQQKRDTFIGTPY-WMAPEVVLCETLKDTPYDFKADIWS 708
Query: 611 FAVCMWEILSFGKQPFFWLENKDVIGVLEKGD--RLPKPDLCPPVLYTLMTRCWDYDPSD 668
V + E + P + V+ + K D L KP + + +C DP+
Sbjct: 707 LGVTLIEFAQI-EPPNKEMHPMRVLIKIHKSDPPTLEKPKKWTKLFKDFIAKCLVKDPNL 531
Query: 669 RPRFTELV 676
RP EL+
Sbjct: 530 RPTAAELL 507
>25550
Length = 941
Score = 48.9 bits (115), Expect = 9e-06, Method: Compositional matrix adjust.
Identities = 27/98 (27%), Positives = 53/98 (54%), Gaps = 3/98 (3%)
Frame = +3
Query: 610 MFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTRCWDYDPSDR 669
M A +W++ G ++ +V +LE+G R+ +P P +Y LM +CW +DP +R
Sbjct: 12 MGACDIWDVXYPG------VDLTEVYHLLERGYRMERPQGTPADVYILMLKCWQWDPKER 173
Query: 670 PRFTELVCSLSDVYQ---MEKDIAMEQERNARYRTPKI 704
P F E+ L ++++ + +++ E E+N + P +
Sbjct: 174 PTFKEIHYLLENMFEKSSISEEVEKELEKNDKKLIPTL 287
>00715
Length = 1788
Score = 48.5 bits (114), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 51/249 (20%), Positives = 102/249 (40%), Gaps = 36/249 (14%)
Frame = +1
Query: 468 KEKFMSEAVIMK-NLDHPHIVKLIGIIE----EEPTWIIMELYPYGELGHYLERNKNSLK 522
++ + +E + + L H ++V ++G E+ W+ ME L L ++ +
Sbjct: 55 RQSYSNELLAFRCGLRHVNVVSILGATSLHRFEDGAWLAMEYVGPLNLQTILNDHQQDID 234
Query: 523 VLTLVLYSLQICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSRYI-------- 574
+ +LQ+ + + YL SIN VH D+ N L+ +++ DFG +
Sbjct: 235 SSMRLSLALQMARGLHYLHSINIVHLDLKPANCLLTRDLKLRIADFGCCHQLTPTGLDMG 414
Query: 575 EDEDYYKASVTRL-PIK------------WMSPESINFRRFTTASDVWMFAVCMWEILSF 621
E E + L P++ + +PE + + + SDV+ + +W++ +
Sbjct: 415 EREGGMAGNELELTPVQGAWKNELAGTLAYRAPELLKGLQPSVRSDVYSLGITLWQMCTR 594
Query: 622 GKQPFFWLENKDVIGVLEKGDRLPKPDLCPP----------VLYTLMTRCWDYDPSDRPR 671
+ P+ + V+ + D P CPP + L T+CW DRP
Sbjct: 595 -QGPYEGVPAHAVVYQVVSKDLRP----CPPPSTEDDPFEVMFRDLYTQCWARRVEDRPT 759
Query: 672 FTELVCSLS 680
++V ++
Sbjct: 760 SLDVVHAIG 786
>01756
Length = 1858
Score = 47.8 bits (112), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 57/233 (24%), Positives = 93/233 (39%), Gaps = 22/233 (9%)
Frame = -3
Query: 461 KDCTLDN-KEKF----MSEAVIMKNLDHPHIVKLIGIIEEEPTWIIMELYPYGELGHYLE 515
K +DN KE F + E I++ L+H ++V LI I + T + + + E
Sbjct: 1649 KKVLMDNEKEGFPITALREIKILQLLNHENVVDLIEICSTKATSANRYKSMFYLVFEFCE 1470
Query: 516 RNKNSLKVLTLVLYSL--------QICKAMAYLESINCVHRDIAVRNILVASPECVKLGD 567
+ L V+++L Q+ + Y+ +HRD+ NIL+ +KL D
Sbjct: 1469 HDLAGLLSNMSVVFNLPEIKEVMKQLMNGLYYIHRNKILHRDMKAANILITKQGVLKLAD 1290
Query: 568 FGLSRY----IEDEDYYKASVTRLPIKWMSPESINF--RRFTTASDVWMFAVCMWEILSF 621
FGL+R + + Y V L W P + R ++TA D W M E+
Sbjct: 1289 FGLARAFSVNLRQPNRYTNRVVTL---WYRPPELLLGDRNYSTAIDQWGAGCIMAEM--- 1128
Query: 622 GKQPFFWLENKDVIGVLEKGDRLPKPDLC---PPVLYTLMTRCWDYDPSDRPR 671
W N + G E+ LC P ++ + R Y+ D P+
Sbjct: 1127 ------WTRNPIMQGTTEQNQLTLITQLCGSITPEVWPGVERLELYNSLDLPQ 987
>12672
Length = 773
Score = 46.2 bits (108), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 38/158 (24%), Positives = 64/158 (40%), Gaps = 16/158 (10%)
Frame = +3
Query: 534 CKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGL---SRYIEDEDYYKASVTRLPIK 590
+ YL VHRDI NIL+ S K+GDF + E + ASV
Sbjct: 21 ASGIQYLNDNGHVHRDIKTANILLDSEYTAKVGDFATVVSAPSGEGKTVQNASVVIGTAA 200
Query: 591 WMSPESINFRRFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPK---- 646
+++PE+I+F +T D + F V + E+++ + E + + + + P+
Sbjct: 201 YLAPEAIHF-DVSTKLDSYSFGVVLLEVITGLVAQDYSREERTLSSHIMENVEEPEEIHD 377
Query: 647 ---------PDLCPPVLYTLMTRCWDYDPSDRPRFTEL 675
PD LY + RC + RP ++
Sbjct: 378 FVDQSAGTWPDGAVDKLYDISMRCLNLSKKQRPNVKDI 491
>26711
Length = 405
Score = 45.4 bits (106), Expect = 1e-04, Method: Composition-based stats.
Identities = 30/99 (30%), Positives = 52/99 (52%), Gaps = 4/99 (4%)
Frame = -2
Query: 532 QICKAMAYLESINCVHRDIAVRNILVASP--ECVKLGDFGLSR--YIEDEDYYKASVTRL 587
Q+ + ++ + VH D+ N+L++ + V+L DFGL+R Y E +
Sbjct: 392 QVLDILQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARKLYPPQETFLNHGTP-- 219
Query: 588 PIKWMSPESINFRRFTTASDVWMFAVCMWEILSFGKQPF 626
+ SPE+++ + +TASDVW V + +LS G+ PF
Sbjct: 218 --GFTSPEALDVKPISTASDVWGVGVLAYILLS-GQSPF 111
>32264
Length = 287
Score = 45.1 bits (105), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 21/45 (46%), Positives = 26/45 (57%)
Frame = +1
Query: 638 LEKGDRLPKPDLCPPVLYTLMTRCWDYDPSDRPRFTELVCSLSDV 682
+E G RL + P +Y LM RCW+Y P RP F EL SL D+
Sbjct: 1 IEDGYRLQQNPQTPDSVYKLMLRCWEYVPEKRPHFKELYTSLKDI 135
>01060
Length = 1800
Score = 44.3 bits (103), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 41/163 (25%), Positives = 77/163 (47%), Gaps = 7/163 (4%)
Frame = +1
Query: 472 MSEAVIMKNLDHPHIVKLIGII-EEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVL-- 528
+ E +++ L H +IV L +I E+E +++ E +L Y+++ + VL L
Sbjct: 214 IREIAMLRELRHTNIVCLEDVIMEDERLFLVFEFLSM-DLKMYIDKFPEGV-VLDRRLVK 387
Query: 529 -YSLQICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSRY--IEDEDYYKASVT 585
Y QI + + VHRD+ +N+L+ +K+ DFG++R + Y VT
Sbjct: 388 SYVFQIVTGIXFCHQRRIVHRDLKPQNLLINHTGAIKIADFGMARTFALPVRAYTHEVVT 567
Query: 586 RLPIKWMSPESI-NFRRFTTASDVWMFAVCMWEILSFGKQPFF 627
+ + +PE + +++T DVW ++L + P F
Sbjct: 568 ---LWYRAPEILMGASKYSTPVDVWSIGTIFADMLI--RTPIF 681
>04591
Length = 1117
Score = 43.9 bits (102), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 27/92 (29%), Positives = 42/92 (45%), Gaps = 3/92 (3%)
Frame = -2
Query: 532 QICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSR-YIEDEDYYKASVTRLPIK 590
Q+ + Y+ + +HRDI NIL+ +KL DFGLSR +++ K R+
Sbjct: 873 QLLNGLFYIHTKQILHRDIKAANILLTRDGVLKLADFGLSRPWVKS----KRLTNRVVTL 706
Query: 591 WMSPESINF--RRFTTASDVWMFAVCMWEILS 620
W P + R + D+W M E+ S
Sbjct: 705 WYRPPELLLGEREYGPEIDMWGVGCIMAEMWS 610
>03240
Length = 1683
Score = 43.1 bits (100), Expect = 6e-04, Method: Compositional matrix adjust.
Identities = 38/140 (27%), Positives = 66/140 (47%), Gaps = 9/140 (6%)
Frame = -3
Query: 455 AVKTCKKDCTLDNKE--KFMSEAVIMKNLDHPHIVKLIGIIEEEP-TWIIMELYPYGELG 511
A+KT +K L + +E I+ D+ +VKL ++ + +M+ P G+L
Sbjct: 1204 AMKTLRKSDVLKRNQVAHVKAERDILAEADNEWVVKLYYSFQDHNYLYFVMDYVPGGDLM 1025
Query: 512 HYLERNKNSLKVLTLVL---YSLQICKAMAYLESINCVHRDIAVRNILVASPECVKLGDF 568
L R +++L L Y ++ +A+ + + +HRDI NIL+ +KL DF
Sbjct: 1024 GLLIR----MEILDEPLARFYVAELVQAIESVHRMGFIHRDIKPDNILIDRNGHIKLTDF 857
Query: 569 GLS---RYIEDEDYYKASVT 585
GL R+ + YY+ T
Sbjct: 856 GLCTGFRWTHNSKYYQRDGT 797
>04138
Length = 800
Score = 42.0 bits (97), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 45/177 (25%), Positives = 71/177 (40%), Gaps = 7/177 (3%)
Frame = +1
Query: 537 MAYLESINCVHRDIAVRNILVASPECVKLGDFGLSRY----IEDEDYYKASVTRLPIKWM 592
+ Y+ +HRD+ NIL+ +KL DFGL+R + + Y V L W
Sbjct: 52 LYYIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTNRVVTL---WY 222
Query: 593 SPESINF--RRFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLC 650
P + R ++TA D W M E+ W N + G E+
Sbjct: 223 RPPELLLGDRNYSTAIDQWGAGCIMAEM---------WTRNPIMQGTTEQNQ-------- 351
Query: 651 PPVLYTLMTR-CWDYDPSDRPRFTELVCSLSDVYQMEKDIAMEQERNARYRTPKILE 706
TL+T+ C P P T+ LS +Q++ +A ++ R R +IL+
Sbjct: 352 ----LTLITQLCGSITPEVWPGVTQ----LSMYHQIKGALAAGRKNIIRDRFARILK 498
>35671
Length = 567
Score = 41.2 bits (95), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 18/50 (36%), Positives = 29/50 (58%)
Frame = -3
Query: 639 EKGDRLPKPDLCPPVLYTLMTRCWDYDPSDRPRFTELVCSLSDVYQMEKD 688
+KG+RL KP C Y +M +CW +RP F +LV + ++Y+ +D
Sbjct: 565 QKGNRLAKPISCTDEAYKVMLQCWTESREERPTFKKLVPVMENLYRSHRD 416
>01966
Length = 1735
Score = 40.8 bits (94), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 38/159 (23%), Positives = 73/159 (45%), Gaps = 9/159 (5%)
Frame = -1
Query: 447 HKGEKINVAVKTCKKDCTLDN-KEKFMSEAVIMKNLDHPHIVKLIGII-EEEPTWIIMEL 504
H+ +A+K + + D + E +++ L H +IV L +I E+E +++ E
Sbjct: 1648 HRATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTNIVCLEDVIMEDERLFLVFEF 1469
Query: 505 YPYGELGHYLERNKNSLKVLTLVL--YSLQICKAMAYLESINCVHRDIAVRNILVASPEC 562
+L Y+++ + + ++ Y QI + + VHRD+ +N+L+
Sbjct: 1468 LSM-DLKMYIDKFPEGVVLDRRLVKSYVFQIVTGINFCHQRRIVHRDLKPQNLLINHTGA 1292
Query: 563 VKLGDFGLSRY--IEDEDYYKASVT---RLPIKWMSPES 596
+K+ DFG++R + Y VT R P M P+S
Sbjct: 1291 IKIADFGMARTFALPVRAYTHEVVTLWYRAPEILMGPQS 1175
>07933
Length = 728
Score = 39.3 bits (90), Expect = 0.007, Method: Compositional matrix adjust.
Identities = 14/29 (48%), Positives = 20/29 (68%)
Frame = +3
Query: 647 PDLCPPVLYTLMTRCWDYDPSDRPRFTEL 675
P+ CP +LY +M +CW +PS RP F +L
Sbjct: 3 PNYCPNLLYNIMMQCWSAEPSARPTFHKL 89
>07836
Length = 1478
Score = 38.5 bits (88), Expect = 0.015, Method: Compositional matrix adjust.
Identities = 48/163 (29%), Positives = 74/163 (45%), Gaps = 25/163 (15%)
Frame = -1
Query: 481 LDHPHIVKLIGI-IEEEPTW----IIMELYPYGELGHYL-ERNKNSLKVLTLVLYSLQIC 534
L H +I+ I I+ +W +I + + G L YL R +S ++L L + IC
Sbjct: 1394 LRHENILGFIAADIKGTGSWTQLFLITDYHENGSLHDYLLSRVLDSSEMLALAHSA--IC 1221
Query: 535 K-AMAYLESINC------VHRDIAVRNILVASPECVKLGDFGLS-RYIEDEDYYKASVTR 586
A ++E HRDI +NILV + D GL+ RYI + + + V
Sbjct: 1220 GLAHLHIEIFGTRGKPAIAHRDIKSKNILVKKNGTCCIADLGLAVRYISESN--EVDVAP 1047
Query: 587 LP----IKWMSPESI-------NFRRFTTASDVWMFAVCMWEI 618
P ++M+PE + NF F A D++ F + MWEI
Sbjct: 1046 NPRQGTKRYMAPEVLEMLLNVKNFDAFKQA-DMYAFGLVMWEI 921
>28157
Length = 400
Score = 37.0 bits (84), Expect = 0.033, Method: Compositional matrix adjust.
Identities = 34/127 (26%), Positives = 59/127 (46%), Gaps = 8/127 (6%)
Frame = +3
Query: 453 NVAVKTCKKDCTLDNKEKFMSEAVIMKNLDHPHIVKLIGIIEEEPTWIIMELYPYGELGH 512
+VAVK + + K+ FM E + + HP+IV L G + P ++ME G L +
Sbjct: 6 DVAVKRIESE---QEKKSFMQELKQLSRVSHPNIVCLYGACRDHPVCLVMEYAEGGSLYN 176
Query: 513 YLERN--KNSLKVLTLVLYSLQICKAMAYLESIN---CVHRDIAVRNILVASPEC---VK 564
L + + + + LQ + YL + +HRD+ N+L+ +C +K
Sbjct: 177 VLHGSGPQPQYTAAHAMNWLLQCALGVEYLHGMKPKALIHRDLKPPNLLLI--QCGTKLK 350
Query: 565 LGDFGLS 571
+ DFG +
Sbjct: 351 ICDFGTA 371
>32359
Length = 928
Score = 36.6 bits (83), Expect = 0.050, Method: Compositional matrix adjust.
Identities = 30/103 (29%), Positives = 51/103 (49%), Gaps = 10/103 (9%)
Frame = -1
Query: 454 VAVKTCKKDCTLDNKEKFMSEAVIMKNLDHPHIVKLIGII-------EEEPTWIIMELYP 506
VA+K +D N+E IM+ L+H +IVKL +E +++E P
Sbjct: 346 VAIKKVLQDKRFKNRE-----LQIMRKLEHQNIVKLKFFFYSSGEKKDEVFLNLVLEYVP 182
Query: 507 ---YGELGHYLERNKNSLKVLTLVLYSLQICKAMAYLESINCV 546
Y HY ++K ++ +L + LY Q+ +++AY+ S CV
Sbjct: 181 ETVYRVARHY-SKSKQTIPILYIKLYMYQLFRSLAYIHSQACV 56
>15741
Length = 402
Score = 35.0 bits (79), Expect = 0.13, Method: Composition-based stats.
Identities = 14/44 (31%), Positives = 24/44 (54%)
Frame = -3
Query: 513 YLERNKNSLKVLTLVLYSLQICKAMAYLESINCVHRDIAVRNIL 556
+L N L ++L + + MA++ + VHRD+A RN+L
Sbjct: 133 FLTSTANDLTARDFFSFALHVARGMAHVANNKIVHRDVAARNVL 2
>01392
Length = 1806
Score = 35.0 bits (79), Expect = 0.16, Method: Compositional matrix adjust.
Identities = 34/129 (26%), Positives = 55/129 (42%), Gaps = 12/129 (9%)
Frame = -1
Query: 511 GHYLERNKNSLKVLTLVLYSLQICKAMAYLESINCVHRDIAVRNILVASPE---CVKLGD 567
GH ER + L I +A+ +L S HRD+ NIL + VK+ D
Sbjct: 1806 GHLCEREAS--------LVVRHIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICD 1651
Query: 568 FGLSRYIE-DEDYYKASVTRLPI---KWMSPESINFR-----RFTTASDVWMFAVCMWEI 618
F L+ I D D K P+ ++M+PE ++ + D+W + ++ I
Sbjct: 1650 FDLASGISCDGDGTKTPELLTPVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILY-I 1474
Query: 619 LSFGKQPFF 627
+ G PF+
Sbjct: 1473 MLCGYPPFY 1447
>38046
Length = 446
Score = 33.9 bits (76), Expect = 0.37, Method: Composition-based stats.
Identities = 16/32 (50%), Positives = 20/32 (62%)
Frame = -1
Query: 533 ICKAMAYLESINCVHRDIAVRNILVASPECVK 564
I AMAY+E N +HR++ RNILV VK
Sbjct: 98 IADAMAYMEKENFIHRNLGDRNILVGPNNRVK 3
>27287
Length = 514
Score = 33.5 bits (75), Expect = 0.40, Method: Compositional matrix adjust.
Identities = 14/34 (41%), Positives = 19/34 (55%)
Frame = -2
Query: 646 KPDLCPPVLYTLMTRCWDYDPSDRPRFTELVCSL 679
KP ++ +M CW DP+DRP F+ LV L
Sbjct: 507 KPPYASSEMFGIMHSCWQEDPNDRPSFSRLVQEL 406
>21433
Length = 590
Score = 32.0 bits (71), Expect = 1.2, Method: Composition-based stats.
Identities = 23/91 (25%), Positives = 38/91 (41%)
Frame = +2
Query: 529 YSLQICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVTRLP 588
Y Q+ A+ Y +HRDI N+L+ +K+ DFG S + T
Sbjct: 182 YIYQLSSALEYCHYRKVIHRDIKPENLLLGLKGDLKIADFGWSVHAPSSRRTTMCGT--- 352
Query: 589 IKWMSPESINFRRFTTASDVWMFAVCMWEIL 619
+ ++ PE + + D+W V +E L
Sbjct: 353 LDYLPPEMVEGKTHDENVDLWSLGVLCYEFL 445
>02638
Length = 1490
Score = 31.6 bits (70), Expect = 1.4, Method: Composition-based stats.
Identities = 24/92 (26%), Positives = 42/92 (45%), Gaps = 4/92 (4%)
Frame = +1
Query: 589 IKWMSPESINFRRFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEK----GDRL 644
I +M+PE + + A DVW M E+ + + P+ + + + ++ K D
Sbjct: 28 IAFMAPEVLRGESYGRACDVWSVGCVMIEMCTC-RPPWNSHDISNHLALIFKIASSVDPP 204
Query: 645 PKPDLCPPVLYTLMTRCWDYDPSDRPRFTELV 676
P P+ P + LM RC + D RP +L+
Sbjct: 205 PIPENMSPPVRDLMLRCLEQDSDFRPSAKDLL 300
>26560
Length = 398
Score = 31.6 bits (70), Expect = 1.6, Method: Composition-based stats.
Identities = 24/99 (24%), Positives = 44/99 (44%)
Frame = -1
Query: 528 LYSLQICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVTRL 587
Y+ ++ + ++ S V+RD+ NIL+ V++ D GL+ + + + T
Sbjct: 344 FYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGLACDFSKKRPHASVGTH- 168
Query: 588 PIKWMSPESINFRRFTTASDVWMFAVCMWEILSFGKQPF 626
+M+PE + + +S W CM L G PF
Sbjct: 167 --GYMAPEVLMKGQSYDSSADWFSFGCMLYKLLKGHSPF 57
>16708
Length = 1397
Score = 31.2 bits (69), Expect = 1.9, Method: Compositional matrix adjust.
Identities = 28/112 (25%), Positives = 46/112 (41%), Gaps = 7/112 (6%)
Frame = -1
Query: 500 IIMELYPYGELGHYLERNKN-------SLKVLTLVLYSLQICKAMAYLESINCVHRDIAV 552
I++ Y G L + KN S + + +C A+ ++ + VH D+
Sbjct: 1184 ILLHFYEMGPLCNVYAHYKNKEMPIRWSNPAMVCCIAGQXVC-ALEHIHELGVVHMDVKA 1008
Query: 553 RNILVASPECVKLGDFGLSRYIEDEDYYKASVTRLPIKWMSPESINFRRFTT 604
N+LV + KL D+G+++ YK V P + S N R F T
Sbjct: 1007 DNVLVDAHGNCKLTDYGIAQ------LYK--VYPAPTETHSSGCTNKRTFYT 876
>37602
Length = 804
Score = 30.0 bits (66), Expect = 5.0, Method: Compositional matrix adjust.
Identities = 15/34 (44%), Positives = 18/34 (52%)
Frame = -1
Query: 535 KAMAYLESINCVHRDIAVRNILVASPECVKLGDF 568
K + YL +HRDI NIL+ VKL DF
Sbjct: 186 KGLHYLHRRGKMHRDIKGANILLTEEGDVKLADF 85
>00302
Length = 927
Score = 29.6 bits (65), Expect = 5.5, Method: Composition-based stats.
Identities = 14/42 (33%), Positives = 24/42 (57%)
Frame = -2
Query: 537 MAYLESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDED 578
+ YL+S+ C+H+ + LVA+ VK F ++R + ED
Sbjct: 458 LVYLDSV-CIHKSVVYEKCLVATDISVKYRLFTIARLVAPED 336
>26009
Length = 886
Score = 29.3 bits (64), Expect = 8.3, Method: Composition-based stats.
Identities = 11/30 (36%), Positives = 19/30 (63%)
Frame = +3
Query: 532 QICKAMAYLESINCVHRDIAVRNILVASPE 561
Q+ A+ ++ S VHRDI N+L+ +P+
Sbjct: 735 QLVSALDFMHSKQLVHRDIKPENVLILTPD 824
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000291041 | hsapiens_gene_ensembl |
Serine/threonine-protein kinase H1 (EC 2.7.11.1) (PSK-H1).
[Source:Uniprot/SWISSPROT;Acc:P11801]
(424 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
15910 200 9e-52
12721 124 6e-29
01392 119 3e-27
21079 114 4e-27
14420 99 4e-21
01060 99 4e-21
18484 96 2e-20
13592 94 7e-20
26711 94 8e-20
09606 94 1e-19
17975 90 2e-18
00300 88 7e-18
30755 88 8e-18
03240 87 1e-17
01718 84 1e-16
01707 83 2e-16
18921 83 2e-16
01966 67 3e-16
13066 81 7e-16
14126 81 7e-16
31885 81 8e-16
21433 61 8e-15
01756 73 2e-13
29581 73 2e-13
00486 73 2e-13
04591 73 3e-13
29590 60 3e-13
00392 70 2e-12
06405 69 3e-12
25019 49 5e-12
27405 68 6e-12
13212 67 1e-11
19094 61 2e-11
26560 65 3e-11
21808 64 9e-11
28157 63 3e-10
38560 62 3e-10
09007 62 4e-10
27274 61 1e-09
20152 60 2e-09
27546 58 6e-09
18663 57 1e-08
26009 39 2e-08
19761 56 2e-08
04852 55 6e-08
11185 54 1e-07
03508 54 2e-07
12786 54 2e-07
19301 51 8e-07
31489 50 2e-06
28638 49 3e-06
36481 49 3e-06
26156 47 4e-06
00715 49 5e-06
31120 48 7e-06
32957 47 1e-05
36002 47 2e-05
07940 47 2e-05
04138 46 3e-05
37602 46 3e-05
07291 45 5e-05
07833 45 8e-05
01106 44 9e-05
11404 44 1e-04
21418 44 2e-04
17300 43 3e-04
37063 42 4e-04
18401 42 5e-04
23319 41 0.001
14116 41 0.001
07836 40 0.002
02638 40 0.002
18481 40 0.002
29360 39 0.004
20655 37 0.011
21800 37 0.011
12672 37 0.013
33586 36 0.027
16350 36 0.031
17722 36 0.035
20513 35 0.058
17516 33 0.16
03294 33 0.19
17932 33 0.23
00638 32 0.61
18996 32 0.62
13305 30 1.6
35032 30 1.7
22005 30 1.9
20773 30 2.0
14104 30 2.1
17644 30 2.2
16708 30 2.5
12517 29 3.5
15549 29 4.7
21210 28 5.2
26909 28 5.6
>15910
Length = 1361
Score = 200 bits (509), Expect = 9e-52, Method: Compositional matrix adjust.
Identities = 100/204 (49%), Positives = 133/204 (65%)
Frame = +2
Query: 179 ELFDRIIAKGSFTERDATRVLQMVLDGVRYLHALGITHRDLKPENLLYYHPGTDSKIIIT 238
ELFDRI+ +G +TE+DA R + +L GV+Y+HA G+ HRDLKPENLLY DSK+ +
Sbjct: 422 ELFDRIVTRGQYTEKDAARAISDILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLA 601
Query: 239 DFGLASARKKGDDCLMKTTCGTPEYIAPEVLVRKPYTNSVDMWALGVIAYILLSGTMPFE 298
DFGL+ R + M T CGTP Y APEVL YT SVDMW++GVIAYILL G PF
Sbjct: 602 DFGLS--RIIEPEVQMSTVCGTPGYCAPEVLKGDKYTPSVDMWSVGVIAYILLCGYEPFF 775
Query: 299 DDNRTRLYRQILRGKYSYSGEPWPSVSNLAKDFIDRLLTVDPGARMTALQALRHPWVVSM 358
+N +YR+I++G+Y + E W +S AKD + +LL +DP R+TA +ALR PWV +
Sbjct: 776 AENEFEMYRKIIKGEYKFDEEYWSEISENAKDVVRKLLVIDPKKRLTATEALRLPWVKGV 955
Query: 359 AASSSMKNLHRSISQNLLKRASSR 382
A K + I+ N LK ++R
Sbjct: 956 AT----KTTNMEITMNKLKEFNAR 1015
>12721
Length = 821
Score = 124 bits (312), Expect = 6e-29, Method: Compositional matrix adjust.
Identities = 89/286 (31%), Positives = 139/286 (48%), Gaps = 13/286 (4%)
Frame = +1
Query: 74 PSEPPRRARVAKYRAKF-------DPRVTAKYDIKALIGRGSFSRVVRVEHRATRQPYAI 126
P P+R ++RA DPR +K IG GS V R RQ A+
Sbjct: 7 PMPEPQRLSHEQFRAALQMVVTPGDPRTFLDDFMK--IGEGSTGIVCIATSRDGRQ-MAV 177
Query: 127 KMIETKYREGREVCESELRVLRRVRHANIIQLVEVFETQERVYMVMELATGGELFDRIIA 186
K ++ + ++ RE+ +E+ V+R H NI+++ + + +++VME GG L D I+
Sbjct: 178 KKMDLRKQQRRELLFNEVVVMRDYHHPNIVEMYNSYLVNDELWVVMEFMEGGALTD-IVT 354
Query: 187 KGSFTERDATRVLQMVLDGVRYLHALGITHRDLKPENLLYYHPGTDSKIIITDFGLASAR 246
E V + L + +LHA G+ HRD+K +++L H D K+ + DFG A+
Sbjct: 355 NNRMDEVQIATVCRACLKALAFLHANGVIHRDIKSDSILLSH---DGKVKLXDFGFC-AQ 522
Query: 247 KKGDDCLMKTTCGTPEYIAPEVLVRKPYTNSVDMWALGVIAYILLSGTMPFEDDNRTRLY 306
D K+ GTP ++APEV+ R PY VD+W+LG++ ++ PF ++ +
Sbjct: 523 VTQDLQKRKSLVGTPYWMAPEVISRLPYGPEVDIWSLGIMVMEMIDAEPPFFNEPPLQAM 702
Query: 307 RQILRGKYSYSGEPWPSVSNLAK------DFIDRLLTVDPGARMTA 346
R+I P P + N K FIDR+L DP R TA
Sbjct: 703 RRI-------RDMPPPKLRNTHKISPRLQGFIDRMLVRDPHQRATA 819
>01392
Length = 1806
Score = 119 bits (298), Expect = 3e-27, Method: Compositional matrix adjust.
Identities = 73/214 (34%), Positives = 106/214 (49%), Gaps = 24/214 (11%)
Frame = -1
Query: 188 GSFTERDATRVLQMVLDGVRYLHALGITHRDLKPENLLYYHPGTDSKIIITDFGLASARK 247
G ER+A+ V++ + + +LH+ GI HRDLKPEN+L H + I DF LAS
Sbjct: 1806 GHLCEREASLVVRHIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGIS 1627
Query: 248 KGDDCL----MKTTCGTPEYIAPEVLV-----RKPYTNSVDMWALGVIAYILLSGTMPF- 297
D + T G+ EY+APEV+ Y D+W+LG+I YI+L G PF
Sbjct: 1626 CDGDGTKTPELLTPVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILYIMLCGYPPFY 1447
Query: 298 ----ED----------DNRTRLYRQILRGKYSYSGEPWPSVSNLAKDFIDRLLTVDPGAR 343
ED D + L+ I G Y + + W S+S+ AKD I LL +P R
Sbjct: 1446 GQCGEDCGWNRGEACHDCQDMLFNSIQDGHYKFPSQEWTSISSSAKDLIRHLLVREPRKR 1267
Query: 344 MTALQALRHPWVVSMAASSSMKNLHRSISQNLLK 377
+A L+HPW+ + A++ + H N +K
Sbjct: 1266 YSAADVLKHPWICTPPAATQLATPHVLTRNNSMK 1165
>21079
Length = 878
Score = 114 bits (285), Expect(2) = 4e-27, Method: Compositional matrix adjust.
Identities = 62/146 (42%), Positives = 84/146 (57%), Gaps = 1/146 (0%)
Frame = +1
Query: 152 HANIIQLVEVFETQERVYMVMELATGGELFDRIIAKG-SFTERDATRVLQMVLDGVRYLH 210
H ++ L + FE + +VME GELF+R+I TERD ++ + GV Y+H
Sbjct: 1 HPKLLMLWDAFEAPRTMVLVMEFVGAGELFERVIRDDFVLTERDCVHFVRQICSGVGYMH 180
Query: 211 ALGITHRDLKPENLLYYHPGTDSKIIITDFGLASARKKGDDCLMKTTCGTPEYIAPEVLV 270
I H DLKPEN+L ++ +I I DFGLA K GD ++ GTPE+IAPEV+
Sbjct: 181 TQSILHLDLKPENVLCVSDNSN-QIKIIDFGLARFYKPGDS--LQVLFGTPEFIAPEVVN 351
Query: 271 RKPYTNSVDMWALGVIAYILLSGTMP 296
+ DMW++GVI YILLSG P
Sbjct: 352 YDEINFTTDMWSIGVICYILLSGLSP 429
Score = 25.0 bits (53), Expect(2) = 4e-27, Method: Compositional matrix adjust.
Identities = 12/32 (37%), Positives = 17/32 (53%)
Frame = +2
Query: 325 SNLAKDFIDRLLTVDPGARMTALQALRHPWVV 356
S+ AKDFI + + RMT Q +H W+
Sbjct: 512 SDNAKDFIGNC*SREKEKRMTIEQCDKHSWLA 607
>14420
Length = 528
Score = 98.6 bits (244), Expect = 4e-21, Method: Compositional matrix adjust.
Identities = 53/168 (31%), Positives = 93/168 (55%)
Frame = +2
Query: 137 REVCESELRVLRRVRHANIIQLVEVFETQERVYMVMELATGGELFDRIIAKGSFTERDAT 196
+E+ +E+ V+R ++ NI+ ++ + E +++VME GG L D ++ + E
Sbjct: 32 KELIINEILVMRENQNPNIVNYLDSYLVGEELWVVMEFLAGGSLTD-VVTETCMDEGQIA 208
Query: 197 RVLQMVLDGVRYLHALGITHRDLKPENLLYYHPGTDSKIIITDFGLASARKKGDDCLMKT 256
V + L + +LH + HRD+K +N+L G D + +TDFG A+ + T
Sbjct: 209 AVCRECLQALEFLHENQVIHRDIKSDNILL---GMDGSVKLTDFGFC-AQLSPEQSKRST 376
Query: 257 TCGTPEYIAPEVLVRKPYTNSVDMWALGVIAYILLSGTMPFEDDNRTR 304
GTP ++APEV+ RK Y +VD+W+LGV+ ++ G P+ ++N R
Sbjct: 377 MVGTPYWMAPEVVTRKQYGPTVDIWSLGVMCIEMIEGEPPYLNENPLR 520
>01060
Length = 1800
Score = 98.6 bits (244), Expect = 4e-21, Method: Compositional matrix adjust.
Identities = 83/294 (28%), Positives = 136/294 (46%), Gaps = 36/294 (12%)
Frame = +1
Query: 104 IGRGSFSRVVRVEHRATRQPYAIKMIETKYREGREVCES--ELRVLRRVRHANIIQLVEV 161
IG G++ V + HRAT + A+K I + E + E+ +LR +RH NI+ L +V
Sbjct: 97 IGEGTYGVVYKCRHRATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTNIVCLEDV 276
Query: 162 FETQERVYMVME-LATGGELFDRIIAKGSFTERDATR--VLQMVLDGVRYLHALGITHRD 218
ER+++V E L+ +++ +G +R + V Q+V G+ + H I HRD
Sbjct: 277 IMEDERLFLVFEFLSMDLKMYIDKFPEGVVLDRRLVKSYVFQIV-TGIXFCHQRRIVHRD 453
Query: 219 LKPENLLYYHPGTDSKIIITDFGLAS-----ARKKGDDCLMKTTCGTPEYIAPEVLV-RK 272
LKP+NLL H G I I DFG+A R + + T Y APE+L+
Sbjct: 454 LKPQNLLINHTGA---IKIADFGMARTFALPVRAYTHEVV------TLWYRAPEILMGAS 606
Query: 273 PYTNSVDMWALGVIAYILLSGTMPFEDDNRTRLYRQILRGKYSYSGEPWP---------- 322
Y+ VD+W++G I +L T F+ D+ +I R + + + WP
Sbjct: 607 KYSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKLPAFNG 786
Query: 323 ---------------SVSNLAKDFIDRLLTVDPGARMTALQALRHPWVVSMAAS 361
+ +L D I+R L DP R++ + L+H + +++ S
Sbjct: 787 MFPLWKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYFLNVDTS 948
>18484
Length = 635
Score = 96.3 bits (238), Expect = 2e-20, Method: Compositional matrix adjust.
Identities = 57/166 (34%), Positives = 88/166 (53%)
Frame = +1
Query: 179 ELFDRIIAKGSFTERDATRVLQMVLDGVRYLHALGITHRDLKPENLLYYHPGTDSKIIIT 238
+L RI +G F E A + G+ +LH GI +RDLK +N++ ++ I I
Sbjct: 1 DLMYRIQQEGKFKEPVAAFYAAEIAVGLFFLHDQGIIYRDLKLDNVML---DSEGHIKIA 171
Query: 239 DFGLASARKKGDDCLMKTTCGTPEYIAPEVLVRKPYTNSVDMWALGVIAYILLSGTMPFE 298
DFG+ GD +T CGTP+YIAPE+++ +PY+ SVD WA GV+ + +L+G PF+
Sbjct: 172 DFGMCKEGMTGD-ATTRTFCGTPDYIAPEIVLYQPYSKSVDWWAYGVLLFEMLAGQPPFD 348
Query: 299 DDNRTRLYRQILRGKYSYSGEPWPSVSNLAKDFIDRLLTVDPGARM 344
++ L+ I SY ++S A LL +P R+
Sbjct: 349 GEDEDELFSSITDHNVSYP----KAMSREAVSLCKGLLMKNPTKRL 474
>13592
Length = 980
Score = 94.4 bits (233), Expect = 7e-20, Method: Compositional matrix adjust.
Identities = 75/265 (28%), Positives = 128/265 (48%), Gaps = 11/265 (4%)
Frame = +2
Query: 104 IGRGSFSRVVRVEHRATRQPYAIKMIETKYREGREV--CESELRVLRRVRHANIIQLVEV 161
IG+G F +V + T + A+K I + E R + EL++L ++H N+++ +
Sbjct: 8 IGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETRALKNVAEELKILEGIKHKNLVRYYGI 187
Query: 162 FETQERVYMVMELATGGELFDRIIAKGSFTERDATRVLQMVLDGVRYLHALGITHRDLKP 221
+E + + MEL + G L + G E + R +L GV LH GI HRD+K
Sbjct: 188 EVHREELLIFMELCSEGTLESLVELTGGLPEALSRRFTAQLLSGVAELHKHGIVHRDIKT 367
Query: 222 ENLLYYHPGTDSKIIITDFGLASARKKGDDC--LMKTTCGTPEYIAPEVLVRKPYTNS-- 277
N ++ G++S + + DFG A + ++ GT Y+APEV + TNS
Sbjct: 368 AN-IFLVDGSNS-LKLGDFGSAVKIQAHTTVPGELQGYVGTQAYMAPEVFTK---TNSDG 532
Query: 278 ----VDMWALGVIAYILLSGTMPFED-DNRTRLYRQILRGKYSYSGEPWPSVSNLAKDFI 332
D+W++G + + SG P+ D+ ++ ++ G+ + E S+S DFI
Sbjct: 533 HGRLADIWSVGCVVVEMASGKRPWAQFDSNFQIMFKVGMGEKPQAPE---SLSQEGHDFI 703
Query: 333 DRLLTVDPGARMTALQALRHPWVVS 357
D L DP R++A++ L + S
Sbjct: 704 DHCLQHDPKQRLSAIELLEQNFCKS 778
>26711
Length = 405
Score = 94.4 bits (233), Expect = 8e-20, Method: Composition-based stats.
Identities = 55/138 (39%), Positives = 81/138 (58%), Gaps = 3/138 (2%)
Frame = -2
Query: 198 VLQMVLDGVRYLHALGITHRDLKPENLLYYHPGTDSKIIITDFGLASARKKGDDCLMKTT 257
V++ VLD ++++HA G+ H DLKP NLL DS + + DFGLA + +
Sbjct: 401 VVKQVLDILQHVHAQGVVHMDLKPSNLLLSGDKLDS-VQLIDFGLARKLYPPQETFLNH- 228
Query: 258 CGTPEYIAPEVLVRKPYTNSVDMWALGVIAYILLSGTMPFEDDNRTRLYRQILRGKYSYS 317
GTP + +PE L KP + + D+W +GV+AYILLSG PF+ D+ T ++ +S+
Sbjct: 227 -GTPGFTSPEALDVKPISTASDVWGVGVLAYILLSGQSPFQADSATESLKKTQTCDWSF- 54
Query: 318 GEPWPSVSNL---AKDFI 332
+ PS SN+ AKDFI
Sbjct: 53 -DVCPSFSNMSQDAKDFI 3
>09606
Length = 1300
Score = 93.6 bits (231), Expect = 1e-19, Method: Compositional matrix adjust.
Identities = 75/279 (26%), Positives = 126/279 (45%), Gaps = 30/279 (10%)
Frame = -3
Query: 104 IGRGSFSRVVRVEHRATRQPYAIKMIETKYREGREVCESELRVLRRVRHANIIQLVEVFE 163
+G+G S + + + T AI IE R EV + +R+ + H N++Q E +E
Sbjct: 1091 LGKGEHSIIYKGRRKGTINFVAIHCIEKCKRP--EVTNT-VRMTHDISHPNVVQFHEWYE 921
Query: 164 TQERVYMVMELATGGELFDRIIAKGSFTERDATRVLQM-VLDGVRYLHALGITHRDLKPE 222
T +++V+EL TGG L D I+A+ + R + ++ G+ Y+H+LGI DL+P
Sbjct: 920 TSNHLWLVVELCTGGSLAD-ILAQDHHLPETSIRDFGIHLVTGLHYIHSLGILFHDLRPS 744
Query: 223 NLLYYHPGTDSKIIITDFGLASAR------------KKGDDCLMKT---------TCGTP 261
+L T + DFGL+ + GD +++ T G+P
Sbjct: 743 KVLL---DTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQWNIQSAEEMMKQVPTSGSP 573
Query: 262 EYIAPEVLVRKPYTNSVDMWALGVIAYILLSGTMPFEDDNRTRLYRQILRGKY------- 314
Y+APEV + D+WALG + Y + SG PF + ++L ++
Sbjct: 572 TYMAPEVFQGAEPSIMSDLWALGCVFYEMFSGHPPFLGETYDITKDKVLNKEFPLPKVKG 393
Query: 315 -SYSGEPWPSVSNLAKDFIDRLLTVDPGARMTALQALRH 352
S +P P NL ++ LL D R++ ++H
Sbjct: 392 SRLSAKPSPEFLNL----LESLLQKDSTRRLSWASLVKH 288
>17975
Length = 449
Score = 90.1 bits (222), Expect = 2e-18, Method: Compositional matrix adjust.
Identities = 49/141 (34%), Positives = 86/141 (60%), Gaps = 4/141 (2%)
Frame = +3
Query: 109 FSRVVRVEHRATRQPYAIKMIE-TKYRE-GREVCESELRVLRRVRHANIIQLVEVFETQE 166
F+ V H T + A+K+I+ TK E R E+R ++ V+H N+++L EV +TQ
Sbjct: 6 FAVVKLARHVFTGEKVAVKVIDKTKLDEVSRSHLFQEVRCMKLVQHPNVVRLYEVIDTQT 185
Query: 167 RVYMVMELATGGELFDRII-AKGSFTERDATRVLQMVLDGVRYLHALGITHRDLKPENLL 225
++Y+++EL GG+++D I+ G E+ A R + +++ + Y H L + HRDLKPEN++
Sbjct: 186 KLYLILELGDGGDMYDYIMRHSGGLEEKLAKRYFRQIVEAISYCHKLHVVHRDLKPENVV 365
Query: 226 YYH-PGTDSKIIITDFGLASA 245
++ PG + +TDFG ++
Sbjct: 366 FFEKPGL---VKLTDFGFSTC 419
>00300
Length = 2318
Score = 87.8 bits (216), Expect = 7e-18, Method: Compositional matrix adjust.
Identities = 74/292 (25%), Positives = 131/292 (44%), Gaps = 10/292 (3%)
Frame = -1
Query: 74 PSEPPRRARVAKYRAKFDPRVTAKYDIKALIGRGSFSRVVRVEHRATRQPYAIKMIE--- 130
P EP R V RV ++ IG G F +V + +T + A+K ++
Sbjct: 1700 PREPDYRINVR--------RVNFRWQRGNKIGEGQFGKVYTAVNMSTGELMALKEMKFQP 1545
Query: 131 TKYREGREVCESELRVLRRVRHANIIQLVEVFETQERVYMVMELATGGELFDRIIAKGSF 190
++ RE+C+ E+++ ++H N+++ V ++ + M ME G + + AK
Sbjct: 1544 NDLQQLREMCD-EIKIFEGIQHENLVKYYGVEVHKDEMLMFMEYCDTGTIEE--AAKMGL 1374
Query: 191 TERDATRVLQMVLDGVRYLHALGITHRDLKPENLLYYHPGTDSKIIITDFGLASARKKGD 250
E R + ++ V +LH I HRD+K N+ ++ + + DFG S + K
Sbjct: 1373 PEYLIRRYTREIVLAVNHLHENSIVHRDIKGANIFLT---SNGHVKLGDFG-CSVKLKSH 1206
Query: 251 DCL---MKTTCGTPEYIAPEVLVRKP---YTNSVDMWALGVIAYILLSGTMPFED-DNRT 303
+ GT Y+APEV + Y + D+W+LG + + +G P+ D DN
Sbjct: 1205 TTMPGEFHNLVGTTAYMAPEVFTQNDQGGYGRAADIWSLGCVVIEMATGKRPWHDLDNNY 1026
Query: 304 RLYRQILRGKYSYSGEPWPSVSNLAKDFIDRLLTVDPGARMTALQALRHPWV 355
++ ++ G + S+S K F+D ++ DP R A Q L H +
Sbjct: 1025 QIMYKVGIGHKPAVPD---SLSVEGKHFLDLIMCHDPAQRALASQLLDHTFT 879
>30755
Length = 1137
Score = 87.8 bits (216), Expect = 8e-18, Method: Compositional matrix adjust.
Identities = 61/177 (34%), Positives = 86/177 (48%), Gaps = 8/177 (4%)
Frame = +2
Query: 190 FTERDATRVLQMVLDGVRYLHALGITHRDLKPENLLYYHPGTDSKIIITDFGLASARKKG 249
FTE ++ + YLH+ GI +RDLK ENLL D I + DFGL K
Sbjct: 23 FTEERTRFYGAEIISALGYLHSQGIIYRDLKLENLLL---DKDGHIKVADFGLC----KE 181
Query: 250 DDCLMKTT---CGTPEYIAPEVLVRKPYTNSVDMWALGVIAYILLSGTMPFEDDNRTRLY 306
D +TT CGTPEY+APEVL Y +VD W GV+ Y ++ G +PF + + L+
Sbjct: 182 DITYGRTTKTFCGTPEYLAPEVLDDNDYGRAVDWWGTGVVMYEMICGRLPFYNRDHDVLF 361
Query: 307 RQILRGKYSYSGEPWPSVSNLAKDFIDRLLTVDPGARMTALQ-----ALRHPWVVSM 358
IL + ++++ AK + LL DP R+ Q HP+ S+
Sbjct: 362 TLILVEDVKFPR----NITDEAKSLLSGLLAKDPRNRLGGGQDDVKEIQAHPFFASI 520
>03240
Length = 1683
Score = 87.4 bits (215), Expect = 1e-17, Method: Compositional matrix adjust.
Identities = 80/296 (27%), Positives = 121/296 (40%), Gaps = 47/296 (15%)
Frame = -3
Query: 87 RAKFDPRVTAKYDIKALIGRGSFSRVVRVEHRATRQPYAIKMI---ETKYREGREVCESE 143
RAK D + K IK L G G+F V T YA+K + + R ++E
Sbjct: 1309 RAKMDKCMFEK--IKTL-GVGAFGEVSLCRKNDTGMLYAMKTLRKSDVLKRNQVAHVKAE 1139
Query: 144 LRVLRRVRHANIIQLVEVFETQERVYMVMELATGGELFDRIIAKGSFTERDATRVLQMVL 203
+L + +++L F+ +Y VM+ GG+L +I E A + ++
Sbjct: 1138 RDILAEADNEWVVKLYYSFQDHNYLYFVMDYVPGGDLMGLLIRMEILDEPLARFYVAELV 959
Query: 204 DGVRYLHALGITHRDLKPENLLYYHPGTDSKIIITDFGLASA------------------ 245
+ +H +G HRD+KP+N+L G I +TDFGL +
Sbjct: 958 QAIESVHRMGFIHRDIKPDNILIDRNG---HIKLTDFGLCTGFRWTHNSKYYQRDGTHAR 788
Query: 246 -------------------------RKKGDDCLMKTTCGTPEYIAPEVLVR-KPYTNSVD 279
RK+ CL + GTP YIAPEVL R YT+ D
Sbjct: 787 QDSMEVKCQLDEQCQCEILKPLERRRKREQRCLAHSLVGTPNYIAPEVLSRLGGYTSVCD 608
Query: 280 MWALGVIAYILLSGTMPFEDDNRTRLYRQILRGKYSYSGEPWPSVSNLAKDFIDRL 335
W++GVI + +L G PF + +++ K ++S AKD I RL
Sbjct: 607 WWSVGVILFEMLVGHPPFYANTPAETQYKVINWKDMLKIPRESNLSQPAKDLILRL 440
>01718
Length = 959
Score = 83.6 bits (205), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 60/187 (32%), Positives = 96/187 (51%), Gaps = 4/187 (2%)
Frame = +3
Query: 104 IGRGSFSRVVRVEHRATRQPYAIKMIETKYREGREVCESELRVLRRVRHANIIQLVEVFE 163
IG G FS V +V HR T Q A+KM R E+++L R++HANI++ + V
Sbjct: 171 IGAGFFSEVFKVTHRITGQVMALKM--NTMTSNRHNMLREVQLLNRLQHANILRFMGVCV 344
Query: 164 TQERVYMVMELATGGELFDRIIAKGSFTERDATRVLQMVLD---GVRYLHALGITHRDLK 220
+ +++ + E G L ++++ K E T+ +Q+ L G+ YLH+ HRDL
Sbjct: 345 HEGQLHALTEYIPSGNL-EQLLEKKD-EELPWTQRIQLTLGLARGLDYLHSTRFIHRDLT 518
Query: 221 PENLLYYHPGTDS-KIIITDFGLASARKKGDDCLMKTTCGTPEYIAPEVLVRKPYTNSVD 279
+N+L +I DFGLA+ D T G+P ++APEVL Y D
Sbjct: 519 SKNILIRREDNHGYHAVIADFGLATKIPDPLDKEKLPTVGSPYWMAPEVLNGHFYNERAD 698
Query: 280 MWALGVI 286
++++G+I
Sbjct: 699 LFSVGII 719
>01707
Length = 757
Score = 83.2 bits (204), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 62/205 (30%), Positives = 102/205 (49%), Gaps = 8/205 (3%)
Frame = +1
Query: 97 KYDIKALIGRGSFSRVVRVEHRATRQPYAIKMIETKYREG------REVCESELRVLRRV 150
KY+ IG GS+ V + ++ T Q AIK K+ E +++ E+R+L+++
Sbjct: 67 KYEKIGKIGEGSYGVVFKCRNKETSQLVAIK----KFVESEDDPLIKKIAMREIRMLKQL 234
Query: 151 RHANIIQLVEVFETQERVYMVMELATGGELFDRIIAKGSFTERDATRVLQMVLDGVRYLH 210
+H N+++L+EVF ++R+++V + L + E R++ L V + H
Sbjct: 235 KHPNLVRLIEVFRRKKRLHLVFDYVDHTLLNELDRYPRGLPEPMVKRIIYQTLLAVNFCH 414
Query: 211 ALGITHRDLKPENLLYYHPGTDSKIIITDFGLASARKK-GDDCLMKTTCGTPEYIAPEVL 269
HRD+KPEN+L G ++ + DFG A GD+ T Y APE+L
Sbjct: 415 QYNTIHRDVKPENILITRQG---QVKLCDFGFARILTGPGDE--YTDYVATRWYRAPELL 579
Query: 270 V-RKPYTNSVDMWALGVIAYILLSG 293
V Y VD+WA+G + LL+G
Sbjct: 580 VGDTQYGPPVDVWAIGCVFAELLTG 654
>18921
Length = 697
Score = 82.8 bits (203), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 57/202 (28%), Positives = 99/202 (49%), Gaps = 3/202 (1%)
Frame = +2
Query: 98 YDIKALIGRGSFSRVVRVEHRATRQPYAIKMIETKYREGREVCESELRVLRRVRHANIIQ 157
+DI +G GS+ V + H+ T Q AIK + + +E+ + E+ ++++ I++
Sbjct: 35 FDILGKLGEGSYGSVFKSLHKETGQVLAIKQVPVD-TDLQEIIK-EISIMQQCDSKYIVK 208
Query: 158 LVEVFETQERVYMVMELATGGELFDRI-IAKGSFTERDATRVLQMVLDGVRYLHALGITH 216
+ +++VME G + D + + + ER+ +L L G+ YLH+ H
Sbjct: 209 YYGSYFKNTDLWIVMEYCGAGSVSDIMRLRNKTLVEREIATILYYTLKGLXYLHSRRKIH 388
Query: 217 RDLKPENLLYYHPGTDSKIIITDFGLASARKKGDDCLMK--TTCGTPEYIAPEVLVRKPY 274
RD+K N+L + G + DFG+A D + K T GTP ++APEV+ Y
Sbjct: 389 RDIKAGNILLNNEGHAK---LADFGVAGQLT---DTMAKRNTVIGTPYWMAPEVIQEIGY 550
Query: 275 TNSVDMWALGVIAYILLSGTMP 296
D+W+LG+ A + G P
Sbjct: 551 DCVADIWSLGITALEMAEGKPP 616
>01966
Length = 1735
Score = 67.0 bits (162), Expect(2) = 3e-16, Method: Compositional matrix adjust.
Identities = 47/132 (35%), Positives = 71/132 (53%), Gaps = 5/132 (3%)
Frame = -1
Query: 117 HRATRQPYAIKMIETKYREGREVCES--ELRVLRRVRHANIIQLVEVFETQERVYMVME- 173
HRAT + A+K I + E + E+ +LR +RH NI+ L +V ER+++V E
Sbjct: 1648 HRATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTNIVCLEDVIMEDERLFLVFEF 1469
Query: 174 LATGGELFDRIIAKGSFTERDATR--VLQMVLDGVRYLHALGITHRDLKPENLLYYHPGT 231
L+ +++ +G +R + V Q+V G+ + H I HRDLKP+NLL H G
Sbjct: 1468 LSMDLKMYIDKFPEGVVLDRRLVKSYVFQIV-TGINFCHQRRIVHRDLKPQNLLINHTGA 1292
Query: 232 DSKIIITDFGLA 243
I I DFG+A
Sbjct: 1291 ---IKIADFGMA 1265
Score = 35.8 bits (81), Expect(2) = 3e-16, Method: Compositional matrix adjust.
Identities = 25/113 (22%), Positives = 47/113 (41%), Gaps = 25/113 (22%)
Frame = -3
Query: 274 YTNSVDMWALGVIAYILLSGTMPFEDDNRTRLYRQILRGKYSYSGEPWP----------- 322
Y+ VD+W++G I +L T F+ D+ +I R + + + WP
Sbjct: 1175 YSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKLPAFNGM 996
Query: 323 --------------SVSNLAKDFIDRLLTVDPGARMTALQALRHPWVVSMAAS 361
+ +L D I+R L DP R++ + L+H + +++ S
Sbjct: 995 FPLWKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYFLNVDTS 837
>13066
Length = 551
Score = 81.3 bits (199), Expect = 7e-16, Method: Compositional matrix adjust.
Identities = 46/145 (31%), Positives = 73/145 (50%), Gaps = 3/145 (2%)
Frame = +3
Query: 143 ELRVLRRVRHANIIQLVEVFETQERVYMVMELATGGELFDRIIAKGSFTERDATRVLQMV 202
EL +L ++ H IIQ+ + + + ++ M A G+L I G E+ A +
Sbjct: 126 ELDLLTKLDHPYIIQIHSILQRXPKNFIFMRFAERGDLLTYIQEVGFVKEKQAKIWFYQM 305
Query: 203 LDGVRYLHALGITHRDLKPENLLYYHPGTDSKIIITDFGLASA--RKKGDDCLMKTTCGT 260
+ YLH+ + HRDLK EN+L + + + DFG A A + G+ + +T CG+
Sbjct: 306 TTALNYLHSYDVAHRDLKCENILL---SSHFNVKLADFGFACACITESGEKYMSRTYCGS 476
Query: 261 PEYIAPEVLVRKPYTNSV-DMWALG 284
Y APE++ PY V D W+LG
Sbjct: 477 AAYAAPEIVYGAPYAPKVADAWSLG 551
>14126
Length = 1265
Score = 81.3 bits (199), Expect = 7e-16, Method: Compositional matrix adjust.
Identities = 82/300 (27%), Positives = 139/300 (46%), Gaps = 41/300 (13%)
Frame = +3
Query: 97 KYDIKALIGRGSFSRVVRV-EHRATRQPYAIKMIETKYREG-------REVCESELRVLR 148
KY+ A+IG G++ V + + R + A+K I E RE+ S L+ L
Sbjct: 192 KYEEVAVIGNGAYGTVYKARDLRNQGEFVAMKRIRLNNTEEGMPMMAIREI--SMLKQLE 365
Query: 149 RVRHANIIQLVEV-----FETQERVYMVME-----LATGGELFDRIIAKGSFTERDATRV 198
+ H N+++L++V + + R+ +V E LAT + + G +R +
Sbjct: 366 QYEHPNVVRLLDVSHNTITDREIRLNLVFEYIEHDLAT---YLAKCPSPGLGPDRIKDLM 536
Query: 199 LQMVLDGVRYLHALGITHRDLKPENLLYYHPGTDSKIIITDFGLASARKKGDDCLMKTTC 258
LQ+ L+GV +LH+ I HRDLKP+NLL D ++ + DFGL AR + T
Sbjct: 537 LQL-LNGVDFLHSNRIVHRDLKPQNLLI---SKDGRLKLADFGL--ARIYSFHMALTTVV 698
Query: 259 GTPEYIAPEVLVRKPYTNSVDMWALGVIAYILLSGTMPFEDDNRTRLYRQILR------- 311
T Y +PEVL++ Y SVD+W+ G I L + F+ + ++I
Sbjct: 699 VTLWYRSPEVLMQAEYGTSVDIWSCGCIFAELFTRRALFKGSSEFDQLKKIFEVIGLPPA 878
Query: 312 ---------GKYSYSGEP-------WPSVSNLAKDFIDRLLTVDPGARMTALQALRHPWV 355
+ S+ P P + AKD ++++L G R+++ ++L HP++
Sbjct: 879 GDWPEGVSVHRNSFRPTPPVPLQTLVPEMDPQAKDLMEKMLVFKSGRRISSRESLLHPYL 1058
>31885
Length = 529
Score = 81.3 bits (199), Expect = 8e-16, Method: Compositional matrix adjust.
Identities = 60/171 (35%), Positives = 90/171 (52%), Gaps = 9/171 (5%)
Frame = -2
Query: 146 VLRRVRHANIIQLVEVFETQERVYMVMELATGGELFDRIIAKGSFTERDATRV----LQM 201
+L R+ H ++ L F+ +E ++MV++L GG+L + + SF E D + L +
Sbjct: 513 MLTRLDHPFLVNLWYAFQDEEDLFMVVDLFLGGDLRYHMQQEVSFRE-DCVKFYLCQLAL 337
Query: 202 VLDGVRYLHALGITHRDLKPENLLYYHPGTDSKIIITDFGLASARKKGDDCLMKTTCGTP 261
VLD YL + I HRD+KP+N+L G +TDF +A+ + DD L +T GT
Sbjct: 336 VLD---YLRSQKIVHRDIKPDNILLDEQG---HCHVTDFNIATQLE--DDELATSTSGTR 181
Query: 262 EYIAPEVL-----VRKPYTNSVDMWALGVIAYILLSGTMPFEDDNRTRLYR 307
Y+APEV R+ Y VD W+LGV + LL PF + T L+
Sbjct: 180 PYMAPEVYGVAINERRGYGFPVDWWSLGVSLFELLKKRRPFSVHSNTSLHE 28
>21433
Length = 590
Score = 60.8 bits (146), Expect(2) = 8e-15, Method: Compositional matrix adjust.
Identities = 50/149 (33%), Positives = 72/149 (48%), Gaps = 4/149 (2%)
Frame = +2
Query: 192 ERDATRVLQMVLDGVRYLHALGITHRDLKPENLLYYHPGTDSKIIITDFGLA----SARK 247
+R A + Q+ + Y H + HRD+KPENLL G + I DFG + S+R+
Sbjct: 167 KRTACYIYQLS-SALEYCHYRKVIHRDIKPENLLL---GLKGDLKIADFGWSVHAPSSRR 334
Query: 248 KGDDCLMKTTCGTPEYIAPEVLVRKPYTNSVDMWALGVIAYILLSGTMPFEDDNRTRLYR 307
T CGT +Y+ PE++ K + +VD+W+LGV+ Y L GT P
Sbjct: 335 T-------TMCGTLDYLPPEMVEGKTHDENVDLWSLGVLCYEFLVGTPPLRPSPTRPPTP 493
Query: 308 QILRGKYSYSGEPWPSVSNLAKDFIDRLL 336
R SG P V+ A+D I +LL
Sbjct: 494 ASPRWT---SGSP-SIVTPGARDLISKLL 568
Score = 37.0 bits (84), Expect(2) = 8e-15, Method: Compositional matrix adjust.
Identities = 16/52 (30%), Positives = 29/52 (55%)
Frame = +3
Query: 143 ELRVLRRVRHANIIQLVEVFETQERVYMVMELATGGELFDRIIAKGSFTERD 194
E+ + +RH NI+++ F + RVY+++E A GEL+ + F E +
Sbjct: 18 EIEIQSHLRHDNILRMFGYFHDKTRVYLILEFAPKGELYKELQRCHKFDENE 173
>01756
Length = 1858
Score = 73.2 bits (178), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 68/254 (26%), Positives = 117/254 (46%), Gaps = 22/254 (8%)
Frame = -3
Query: 96 AKYDIKALIGRGSFSRVVRVEHRATRQPYAIK-MIETKYREGREVCE-SELRVLRRVRHA 153
AKY+ A IG+G+F V + + T+Q A+K ++ +EG + E+++L+ + H
Sbjct: 1742 AKYEKLAKIGQGTFGEVFKARCKKTKQVVAMKKVLMDNEKEGFPITALREIKILQLLNHE 1563
Query: 154 NIIQLVEVFETQ--------ERVYMVMELAT---GGELFDRIIAKGSFTERDATRVLQMV 202
N++ L+E+ T+ Y+V E G L + + F + V++ +
Sbjct: 1562 NVVDLIEICSTKATSANRYKSMFYLVFEFCEHDLAGLLSNMSVV---FNLPEIKEVMKQL 1392
Query: 203 LDGVRYLHALGITHRDLKPENLLYYHPGTDSKIIITDFGLASARKKGDDCLMKTT--CGT 260
++G+ Y+H I HRD+K N+L G + + DFGLA A + T T
Sbjct: 1391 MNGLYYIHRNKILHRDMKAANILITKQGV---LKLADFGLARAFSVNLRQPNRYTNRVVT 1221
Query: 261 PEYIAPEVLV-RKPYTNSVDMWALGVIAYIL------LSGTMPFEDDNRTRLYRQILRGK 313
Y PE+L+ + Y+ ++D W G I + + GT + N+ L Q+
Sbjct: 1220 LWYRPPELLLGDRNYSTAIDQWGAGCIMAEMWTRNPIMQGTT---EQNQLTLITQLCG-- 1056
Query: 314 YSYSGEPWPSVSNL 327
S + E WP V L
Sbjct: 1055 -SITPEVWPGVERL 1017
>29581
Length = 1278
Score = 73.2 bits (178), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 66/193 (34%), Positives = 90/193 (46%), Gaps = 12/193 (6%)
Frame = -2
Query: 147 LRRVRHANIIQLVEVF--ETQERVYMVMELATG--GELFDRIIAKGSFTERDATRVLQMV 202
L +RH NI+QL EV ++ + +++VME L D + A F+E ++ +
Sbjct: 1193 LLNLRHQNIVQLQEVVVGKSLDSLFLVMEYCEQDLASLLDNMPA--PFSESQVKCIVLQL 1020
Query: 203 LDGVRYLHALGITHRDLKPENLLYYHPGTDSKIIITDFGLASARKKGDDCLMKTTCGTPE 262
L G+RYLH I HRDLK NLL G + I DFGLA K M T
Sbjct: 1019 LKGLRYLHEAFIIHRDLKVSNLLMTDKGC---VKIADFGLARNYGKPQKP-MTPKVVTLW 852
Query: 263 YIAPEVLV-RKPYTNSVDMWALGVIAYILLSG--TMPFEDD-NRTRLYRQILRGKYSYSG 318
Y APE+L K ++ ++DMW+ G I LL MP D + L ++L G
Sbjct: 851 YRAPELLFGSKTHSTAIDMWSAGCILGELLGHKPLMPGRSDLQQIELIMELL-------G 693
Query: 319 EP----WPSVSNL 327
P WP S L
Sbjct: 692 TPNDTIWPGFSQL 654
>00486
Length = 797
Score = 72.8 bits (177), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 35/89 (39%), Positives = 55/89 (61%)
Frame = -2
Query: 256 TTCGTPEYIAPEVLVRKPYTNSVDMWALGVIAYILLSGTMPFEDDNRTRLYRQILRGKYS 315
T CGT EY+APE+L R + +VD W+LG + Y +L+G+ PF +NR + +IL+GK +
Sbjct: 781 TFCGTIEYMAPEILTRTGHGKAVDWWSLGALMYDMLTGSPPFTAENRKKTIDKILKGKLN 602
Query: 316 YSGEPWPSVSNLAKDFIDRLLTVDPGARM 344
P ++N A+ I +LL +P R+
Sbjct: 601 LP----PYLTNEARGLIKKLLRKNPAERL 527
>04591
Length = 1117
Score = 72.8 bits (177), Expect = 3e-13, Method: Compositional matrix adjust.
Identities = 65/261 (24%), Positives = 105/261 (40%), Gaps = 41/261 (15%)
Frame = -2
Query: 143 ELRVLRRVRHANIIQLVEVFETQ--------ERVYMVMELATG--GELFDRIIAKGSFTE 192
E+++L+++ H N++QL E+ TQ Y++ E L + + K F+
Sbjct: 1071 EIKILQQLEHENVVQLQEICHTQAGPYNRYKSTFYLIFEYCDYDLAGLLNNLRVK--FSL 898
Query: 193 RDATRVLQMVLDGVRYLHALGITHRDLKPENLLYYHPGTDSKIIITDFGLASARKKGDDC 252
D ++ +L+G+ Y+H I HRD+K N+L G + + DFGL+ K
Sbjct: 897 ADKKNLMSQLLNGLFYIHTKQILHRDIKAANILLTRDGV---LKLADFGLSRPWVKSKRL 727
Query: 253 LMKTTCGTPEYIAPEVLV-RKPYTNSVDMWALGVIAYILLSGTMPFEDDNRTRLYRQILR 311
+ T Y PE+L+ + Y +DMW +G I + S + + I
Sbjct: 726 TNRVV--TLWYRPPELLLGEREYGPEIDMWGVGCIMAEMWSRKPLMQGRSEQHQLSLITD 553
Query: 312 GKYSYSGEPWPSVSNL----------------------------AKDFIDRLLTVDPGAR 343
S + E WP V+ L + ID L +DPG R
Sbjct: 552 LCGSLNAEVWPGVTKLELYGKLDLPQGKPRKVKERMLDLLKNKEGAELIDIFLRLDPGQR 373
Query: 344 MTALQALRHP--WVVSMAASS 362
M AL H WV + + S
Sbjct: 372 MNCDNALSHDFFWVDPLPSPS 310
>29590
Length = 320
Score = 59.7 bits (143), Expect(2) = 3e-13, Method: Composition-based stats.
Identities = 25/59 (42%), Positives = 38/59 (64%)
Frame = +3
Query: 239 DFGLASARKKGDDCLMKTTCGTPEYIAPEVLVRKPYTNSVDMWALGVIAYILLSGTMPF 297
D G A G+D ++ GTP+Y+APEVL +P + DMW+LGV++Y++L+ PF
Sbjct: 6 DLGFACLTNTGED--IRDIIGTPDYVAPEVLDYEPLSIQTDMWSLGVLSYVMLTACSPF 176
Score = 32.7 bits (73), Expect(2) = 3e-13, Method: Composition-based stats.
Identities = 17/46 (36%), Positives = 25/46 (54%)
Frame = +2
Query: 300 DNRTRLYRQILRGKYSYSGEPWPSVSNLAKDFIDRLLTVDPGARMT 345
DN+ + I + K + + + +S AKDFI +LL DP RMT
Sbjct: 182 DNQQETFCNISQVKLDFPDDLFSHISPHAKDFIKKLLVKDPRHRMT 319
>00392
Length = 668
Score = 70.1 bits (170), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 50/184 (27%), Positives = 89/184 (48%), Gaps = 8/184 (4%)
Frame = +3
Query: 137 REVCESELRVLRRVRHANIIQLVEVFETQER-----VYMVMELATGGELFDRIIAKGSFT 191
R+ + E +L+ ++H NI++ + +E + +V EL T G L +
Sbjct: 63 RQRFKEEAEMLKELQHPNIVRFFDYWEEHNHRNRKVIILVTELMTSGTLKTYLKRFKKPN 242
Query: 192 ERDATRVLQMVLDGVRYLHALG--ITHRDLKPENLLYYHPGTDSKIIITDFGLASARKKG 249
+ + VL G+ +LH + HRDLK +N+ P KI D GLA+ + +
Sbjct: 243 VKILKNWCRQVLKGLYFLHTRTPPVIHRDLKCDNIFITGPTGSVKI--GDLGLATLKNQS 416
Query: 250 DDCLMKTTCGTPEYIAPEVLVRKPYTNSVDMWALGVIAYILLSGTMPF-EDDNRTRLYRQ 308
K+ GTPE++APE + + Y +VD++A G+ + S P+ E N ++Y++
Sbjct: 417 ---FAKSVIGTPEFMAPE-MYEEHYDEAVDVYAFGMCMLEMASSEYPYSECSNAAQIYKR 584
Query: 309 ILRG 312
+ G
Sbjct: 585 VTSG 596
>06405
Length = 1965
Score = 69.3 bits (168), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 57/219 (26%), Positives = 96/219 (43%), Gaps = 6/219 (2%)
Frame = +1
Query: 100 IKALIGRGSFSRVVRVEHRATRQPYAIKMIETKYREGREVCESELRVLRRVRHANIIQLV 159
+K +G G + V + + A+K ++ + E E +++ ++H N++QL+
Sbjct: 271 MKHRLGGGQYGDVYEAMWKRYNKIVAVKTLKEDTMALNDFLE-EAAIMKEMKHPNLVQLL 447
Query: 160 EVFETQERVYMVMELATGGELFDRIIAKGSFTERDATRVLQM---VLDGVRYLHALGITH 216
V + Y+V E G L D + + E T ++ M + G+ YL H
Sbjct: 448 GVCTREPPFYIVTEFMPHGNLLD-YLRSSTREENGPTALMYMATQIASGMAYLETKNFIH 624
Query: 217 RDLKPENLLYYHPGTDSKII-ITDFGLASARKKGDDCLMKTTCGTP-EYIAPEVLVRKPY 274
RDL N L DS ++ + DFGLA K D P ++ APE L +
Sbjct: 625 RDLAARNCLV----ADSNMVKVADFGLARLMKD-DTYTAHIGAKFPIKWTAPEGLAFNRF 789
Query: 275 TNSVDMWALGVIAYILLS-GTMPFEDDNRTRLYRQILRG 312
+ D+WA GV+ + L + G P+ T +Y + RG
Sbjct: 790 STRSDIWAFGVLLWELATYGMSPYPGVELTEVYHLLERG 906
>25019
Length = 730
Score = 48.5 bits (114), Expect(2) = 5e-12, Method: Compositional matrix adjust.
Identities = 23/53 (43%), Positives = 31/53 (58%)
Frame = +3
Query: 232 DSKIIITDFGLASARKKGDDCLMKTTCGTPEYIAPEVLVRKPYTNSVDMWALG 284
D + +TDFGL G + T CGT EY+APE+L R + +VD W+LG
Sbjct: 282 DGHVKLTDFGLCKEAITGTR-VTHTFCGTIEYMAPEILTRTGHGKAVDWWSLG 437
Score = 40.0 bits (92), Expect(2) = 5e-12, Method: Compositional matrix adjust.
Identities = 21/65 (32%), Positives = 37/65 (56%)
Frame = +1
Query: 280 MWALGVIAYILLSGTMPFEDDNRTRLYRQILRGKYSYSGEPWPSVSNLAKDFIDRLLTVD 339
+W G + Y +L+G+ PF +NR + +IL+GK + P ++N A+ I +LL +
Sbjct: 430 VW--GALMYDMLTGSPPFTAENRKKTIDKILKGKLNLP----PYLTNEARGLIKKLLRKN 591
Query: 340 PGARM 344
P R+
Sbjct: 592 PAERL 606
>27405
Length = 532
Score = 68.2 bits (165), Expect = 6e-12, Method: Compositional matrix adjust.
Identities = 51/182 (28%), Positives = 88/182 (48%), Gaps = 8/182 (4%)
Frame = -3
Query: 108 SFSRVVRVEHRATRQPYAIKMIE---TKYREGREVCESELRVLRRVRHAN----IIQLVE 160
F V T + YA+K ++ K + G + +E +L V I+ +
Sbjct: 530 GFGEVYGCRKADTGKMYAMKCLDKKRIKMKGGETLALNERIMLSLVSTGEGSPFIVCMTY 351
Query: 161 VFETQERVYMVMELATGGELFDRIIAKGSFTERDATRVLQMVLDGVRYLHALGITHRDLK 220
F+T E++ +++L GG+L + G FTE++ V+ G+ ++H+ + +RDLK
Sbjct: 350 AFQTPEKLCFILDLMNGGDLHYHLSQHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLK 171
Query: 221 PENLLYYHPGTDSKIIITDFGLASARKKGDDCLMKTTCGTPEYIAPEVLVR-KPYTNSVD 279
P N+L G + I+D GLA K + GT Y+APEVL++ + Y +S D
Sbjct: 170 PANILLDENG---HVRISDLGLACDFSKKKP---HASVGTHGYMAPEVLMKGQAYDSSAD 9
Query: 280 MW 281
+
Sbjct: 8 WF 3
>13212
Length = 1067
Score = 67.4 bits (163), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 52/168 (30%), Positives = 80/168 (47%), Gaps = 7/168 (4%)
Frame = -1
Query: 201 MVLDGVRYLHALGITHRDLKPENLLYYHPGTDSKIIITDFGLASARKKGDDCLMKTTCGT 260
M LD +LH + HRD+K N+L D ++ + DFG+ SA+ T GT
Sbjct: 947 MALD---FLHRHHVIHRDIKAGNVLL---TIDGEVKLADFGV-SAKNTQTQQKRDTFIGT 789
Query: 261 PEYIAPEVLV-----RKPYTNSVDMWALGVIAYILLSGTMPFEDDNRTRLYRQILRGKYS 315
P ++APEV++ PY D+W+LGV P ++ + R+ +I +
Sbjct: 788 PYWMAPEVVLCETLKDTPYDFKADIWSLGVTLIEFAQIEPPNKEMHPMRVLIKIHKSDPP 609
Query: 316 YSGEP--WPSVSNLAKDFIDRLLTVDPGARMTALQALRHPWVVSMAAS 361
+P W + L KDFI + L DP R TA + L HP++ A+
Sbjct: 608 TLEKPKKW---TKLFKDFIAKCLVKDPNLRPTAAELLEHPFMKRATAT 474
>19094
Length = 898
Score = 60.8 bits (146), Expect(2) = 2e-11, Method: Compositional matrix adjust.
Identities = 37/112 (33%), Positives = 56/112 (50%), Gaps = 2/112 (1%)
Frame = +1
Query: 189 SFTERDATRVLQMVLDGVRYLHALGITHRDLKPENLLYYHPGTDSKIIITDFGLASARKK 248
+ ER+ +L L G+ YLH+ HRD+K N+L + G + DFG+A
Sbjct: 46 TLVEREIATILYYTLKGL*YLHSRRKIHRDIKAGNILLNNEGHAK---LADFGVAGQLT- 213
Query: 249 GDDCLMK--TTCGTPEYIAPEVLVRKPYTNSVDMWALGVIAYILLSGTMPFE 298
D + K T GTP ++APEV+ Y D+W+LG+ A + G + E
Sbjct: 214 --DTMAKRNTVIGTPYWMAPEVIQEIGYDCVADIWSLGITALEMAEGNLHME 363
Score = 25.8 bits (55), Expect(2) = 2e-11, Method: Compositional matrix adjust.
Identities = 11/40 (27%), Positives = 21/40 (52%)
Frame = +3
Query: 330 DFIDRLLTVDPGARMTALQALRHPWVVSMAASSSMKNLHR 369
DF+ + L +P R TA+ L+H ++ A ++ + R
Sbjct: 453 DFVSKCLVKNPENRATAVDLLQHDFIKKAEACEILQAMIR 572
>26560
Length = 398
Score = 65.5 bits (158), Expect = 3e-11, Method: Compositional matrix adjust.
Identities = 41/125 (32%), Positives = 65/125 (52%), Gaps = 1/125 (0%)
Frame = -1
Query: 179 ELFDRIIAKGSFTERDATRVLQMVLDGVRYLHALGITHRDLKPENLLYYHPGTDSKIIIT 238
+L + G FTE++ V+ G+ ++H+ + +RDLKP N+L G + I+
Sbjct: 398 DLHYHLSQHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLDENG---HVRIS 228
Query: 239 DFGLASARKKGDDCLMKTTCGTPEYIAPEVLVR-KPYTNSVDMWALGVIAYILLSGTMPF 297
D GLA K + GT Y+APEVL++ + Y +S D ++ G + Y LL G PF
Sbjct: 227 DLGLACDFSKKRP---HASVGTHGYMAPEVLMKGQSYDSSADWFSFGCMLYKLLKGHSPF 57
Query: 298 EDDNR 302
N+
Sbjct: 56 RQHNQ 42
>21808
Length = 1011
Score = 64.3 bits (155), Expect = 9e-11, Method: Compositional matrix adjust.
Identities = 47/193 (24%), Positives = 92/193 (47%), Gaps = 3/193 (1%)
Frame = +1
Query: 123 PYAIKMIETKYREGREVCESELRVLRRVRHANIIQLVEVFETQERVYMVMELATGGELFD 182
P AIK +++ + ++ +E ++++++RH +IQL V + ++++ EL G L +
Sbjct: 25 PVAIKTLKSGTMDPKDFL-AEAQIMKKLRHPKLIQLYAVCTQDDPIFIITELMKNGSLLE 201
Query: 183 RIIAKGSFTERDA-TRVLQMVLDGVRYLHALGITHRDLKPENLLYYHPGTDSKIIITDFG 241
+ KG + A + + G+ YL + HRDL N+L ++ + I DFG
Sbjct: 202 FLQGKGRVLKLPALIDIGAQIACGMAYLESQNYIHRDLAARNILV---SDNNTVKIADFG 372
Query: 242 LASARKKGDDCLMKTTCGTP-EYIAPEVLVRKPYTNSVDMWALGV-IAYILLSGTMPFED 299
LA K+ D+ + P ++ APE +T D+W+ G+ + + G +P+
Sbjct: 373 LARVIKE-DEYEARVGARFPIKWTAPEAANYNRFTIKSDVWSFGILLTETVTYGRVPYPG 549
Query: 300 DNRTRLYRQILRG 312
+ Q+ G
Sbjct: 550 MTNAEVLHQVEHG 588
>28157
Length = 400
Score = 62.8 bits (151), Expect = 3e-10, Method: Composition-based stats.
Identities = 46/125 (36%), Positives = 64/125 (51%), Gaps = 6/125 (4%)
Frame = +3
Query: 125 AIKMIETKYREGREVCESELRVLRRVRHANIIQLVEVFETQERVYMVMELATGGELFDRI 184
A+K IE++ + ++ EL+ L RV H NI+ L V +VME A GG L++ +
Sbjct: 12 AVKRIESE--QEKKSFMQELKQLSRVSHPNIVCLYGACRDHP-VCLVMEYAEGGSLYNVL 182
Query: 185 IAKGSFTERDATRVLQMVLD---GVRYLHAL---GITHRDLKPENLLYYHPGTDSKIIIT 238
G + A + +L GV YLH + + HRDLKP NLL GT K+ I
Sbjct: 183 HGSGPQPQYTAAHAMNWLLQCALGVEYLHGMKPKALIHRDLKPPNLLLIQCGT--KLKIC 356
Query: 239 DFGLA 243
DFG A
Sbjct: 357 DFGTA 371
>38560
Length = 479
Score = 62.4 bits (150), Expect = 3e-10, Method: Compositional matrix adjust.
Identities = 46/152 (30%), Positives = 74/152 (48%), Gaps = 7/152 (4%)
Frame = -3
Query: 240 FGLASARKKGD-DCLMKTTCGTPEYIAPEVLVRKPYTNS-VDMWALGVIAYILLSGTMPF 297
FG A KG D + T CG+P Y APE++ Y S D+W++GV+ Y LL G +PF
Sbjct: 459 FGTLCA*PKGGMDHHLTTCCGSPAYAAPELISGLEYLGSEADIWSMGVLLYALLCGYLPF 280
Query: 298 EDDNRTRLYRQILRGKYSYSGEPWPSVSNLAKDFIDRLLTVDPGARMTALQALRHPWV-- 355
+D+ + L ++ + K W +S ++ +L DP R+T + L H W+
Sbjct: 279 DDEKXSHL*QKNQKRKDEVP--EW--LSEDTTKLLEGMLQTDPSHRITIRRLLDHHWLNQ 112
Query: 356 ---VSMAASSSMKNLHRSISQNLLKRASSRCQ 384
V + +S K R++ ++ L A Q
Sbjct: 111 GFNVPVEWASKYK---RTLDEDCLTEAGGPIQ 25
>09007
Length = 1440
Score = 62.4 bits (150), Expect = 4e-10, Method: Compositional matrix adjust.
Identities = 62/264 (23%), Positives = 114/264 (43%), Gaps = 17/264 (6%)
Frame = -1
Query: 63 PGPPTAGHTEPPSEPPRRARVAKYRAKFDPRVTAKYDIKAL---IGRGSFSRV---VRVE 116
P PP + P S R AR + +K D AL +G+G F V +
Sbjct: 960 PSPPEHRMSRPVSAVVRPARGKQLISK---------DCVALSKSLGQGHFGTVRQAIWTA 808
Query: 117 HRATRQPYAIKMIETK--YREGREVCESELRVLRRVRHANIIQLVEV-FETQERVYMVME 173
+ A+K + +++G+E + E +++ + H NI+++ V + + +V E
Sbjct: 807 ESGEKVQVAVKCLSKDKIHKDGQEFLK-ETAIMQMLDHENIVRVYGVVMDNGADIMLVTE 631
Query: 174 LATGGELFD---RIIAKGSFTERDATRVLQMVLDGVRYLHALGITHRDLKPENLLYYHPG 230
LA L + + A+ F+ Q V DG+ YL + + HRDL N+L +
Sbjct: 630 LAPMRSLLECVKEVSARVDFSVPRLCDFSQQVCDGMSYLESKRLVHRDLAARNILLF--- 460
Query: 231 TDSKIIITDFGLASARKKGDDCLMKTTC----GTPEYIAPEVLVRKPYTNSVDMWALGVI 286
+ SK+ I+D G++ A G + + APE ++++ D+WA GV+
Sbjct: 459 SKSKVKISDVGVSGALGAGKEYYQSQQTIHLQNAVAWCAPESFRNLCFSSASDVWAFGVL 280
Query: 287 AYILLS-GTMPFEDDNRTRLYRQI 309
+ + G P+ N ++ +
Sbjct: 279 LWEFFTHGFQPWAGLNGQQIMEAV 208
>27274
Length = 396
Score = 60.8 bits (146), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 34/99 (34%), Positives = 56/99 (56%), Gaps = 8/99 (8%)
Frame = -1
Query: 265 APEVLVRKPYTNSVDMWALGVIAYILLSGTMPFEDDNRTR--------LYRQILRGKYSY 316
E+L + + +VDMW+LG++ + LLSG +PFE + +R +Y QI+RG S
Sbjct: 381 GAELLRGQQHGPTVDMWSLGILLHELLSGHVPFEPERGSRQMARNMMAVYAQIIRGS-SR 205
Query: 317 SGEPWPSVSNLAKDFIDRLLTVDPGARMTALQALRHPWV 355
++S DF+ RL+ ++ R+T+ QA HPW+
Sbjct: 204 DVCDGLALSTHGADFLRRLVQLEDTKRLTSQQAFSHPWI 88
>20152
Length = 445
Score = 59.7 bits (143), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 30/91 (32%), Positives = 51/91 (56%), Gaps = 1/91 (1%)
Frame = +1
Query: 266 PEVLVRKPY-TNSVDMWALGVIAYILLSGTMPFEDDNRTRLYRQILRGKYSYSGEPWPSV 324
PE+L+ Y +VD+W+LGVI Y+L+ G PF++ N + I+ +Y P +
Sbjct: 1 PEILLGDSYDAPAVDVWSLGVILYMLVVGEAPFQEANDSETLTMIMDCRYQIP----PHI 168
Query: 325 SNLAKDFIDRLLTVDPGARMTALQALRHPWV 355
S+ +D I+++L +P R + L HPW+
Sbjct: 169 SHKCQDLIEKMLQREPVDRASLPHILAHPWL 261
>27546
Length = 426
Score = 58.2 bits (139), Expect = 6e-09, Method: Compositional matrix adjust.
Identities = 32/101 (31%), Positives = 49/101 (48%)
Frame = -1
Query: 143 ELRVLRRVRHANIIQLVEVFETQERVYMVMELATGGELFDRIIAKGSFTERDATRVLQMV 202
EL +L R+ H NIIQ+ + + ++++ M A G++ I G E +
Sbjct: 330 ELEILTRLDHPNIIQIHSILQRGPKIFIFMRYAEKGDMLSHIKKTGPIDEAQTKVWFFQM 151
Query: 203 LDGVRYLHALGITHRDLKPENLLYYHPGTDSKIIITDFGLA 243
++YLH+ I HRDLK EN+L + I DFG A
Sbjct: 150 AKALQYLHSHDIAHRDLKCENILL---SKRLNVKIADFGFA 37
>18663
Length = 600
Score = 57.0 bits (136), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 25/43 (58%), Positives = 31/43 (72%)
Frame = +2
Query: 256 TTCGTPEYIAPEVLVRKPYTNSVDMWALGVIAYILLSGTMPFE 298
T CGTP YIAPE+L + Y SVD WALGV+ Y +L+G PF+
Sbjct: 5 TFCGTPNYIAPEILRGEDYGFSVDWWALGVLLYEMLAGRSPFD 133
>26009
Length = 886
Score = 38.9 bits (89), Expect(2) = 2e-08, Method: Compositional matrix adjust.
Identities = 29/89 (32%), Positives = 45/89 (50%), Gaps = 2/89 (2%)
Frame = +2
Query: 98 YDIKALIGRGSFSRVVRVEHRATRQPYAIKMIETKYREGREVCESELRVLRRVR-HANII 156
YD+ +GRG++ +VV R T A+K++ + RE + E ++ + HANII
Sbjct: 422 YDVCKELGRGTYGKVVLARCRHTGTQVALKLLPKSCTKLREF-QREFQLSYFLSPHANII 598
Query: 157 QLVEV-FETQERVYMVMELATGGELFDRI 184
V F+T+ E A G+LFD I
Sbjct: 599 DTYNVAFQTRSSYVFAQEHAVLGDLFDAI 685
Score = 37.7 bits (86), Expect(2) = 2e-08, Method: Compositional matrix adjust.
Identities = 13/38 (34%), Positives = 25/38 (65%)
Frame = +3
Query: 192 ERDATRVLQMVLDGVRYLHALGITHRDLKPENLLYYHP 229
R+A V++ ++ + ++H+ + HRD+KPEN+L P
Sbjct: 708 SREAKSVMKQLVSALDFMHSKQLVHRDIKPENVLILTP 821
>19761
Length = 473
Score = 56.2 bits (134), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 48/164 (29%), Positives = 76/164 (46%), Gaps = 7/164 (4%)
Frame = -3
Query: 183 RIIAKGSFT----ERDATRVLQMVLDGVRYLHALG--ITHRDLKPENLLYYHPGTDSKII 236
+I+ FT ER L + Y+H I HRDLKP+N+ G +
Sbjct: 465 KIVGHLGFTAGLPERLIVCWLMQTASALNYMHTHTPVILHRDLKPQNIYVTEKG---DVR 295
Query: 237 ITDFGLASARKKGDDCLMKTTCGTPEYIAPEVLVRKPYTNSVDMWALGVIAYILLSGTMP 296
+ D GLA + G + GT Y++PE+L ++PY + D+W+LG + Y ++G
Sbjct: 294 LGDLGLAR-KLTGPADFATSQVGTIMYLSPEILSQQPYNSKSDIWSLGCVFYD-ITGKKG 121
Query: 297 FEDDNRTRLYRQILRGKYSYSGEPWPS-VSNLAKDFIDRLLTVD 339
++ L Q++ G+ P P S +D I R+LT D
Sbjct: 120 SDEMGVMFLLVQVMGGR----KLPLPDHYSQEFRDTISRMLTKD 1
>04852
Length = 1462
Score = 55.1 bits (131), Expect = 6e-08, Method: Compositional matrix adjust.
Identities = 50/204 (24%), Positives = 90/204 (44%), Gaps = 32/204 (15%)
Frame = +1
Query: 143 ELRVLRRVR----HANIIQLVEVFETQERVYMVMELATGGELFDRIIA------------ 186
EL+V++ V+ H NI+ + +++++E A G L D + +
Sbjct: 88 ELQVMKAVKKMGSHINIVNFLGCCTQGGPLWVIVEFAKNGNLRDFLESCRDGINGYGKFV 267
Query: 187 ----KGSFTERDATRVLQ---------MVLDGVRYLHALGITHRDLKPENLLYYHPGTDS 233
G +T+ V++ + G+ +L + HRDL N+L T+
Sbjct: 268 SPQDPGWYTKTPGGHVIRRKNLLSYAFQIARGMEFLASRKCIHRDLAARNVLV----TEE 435
Query: 234 KII-ITDFGLASARKKGDDCLMKTTCGTP-EYIAPEVLVRKPYTNSVDMWALGVIAYILL 291
++ I DFGL+ + GD ++ P +++APE L YT D+W+ GV+ + +
Sbjct: 436 HVLKIADFGLS---RTGDYYKKRSGGRLPVKWMAPEALFDMRYTTKSDVWSFGVVLWEIF 606
Query: 292 S-GTMPFEDDNRTRLYRQILRGKY 314
S G MP+ LY ++L Y
Sbjct: 607 SLGGMPYASIPNEELYSKLLDDAY 678
>11185
Length = 473
Score = 53.5 bits (127), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 35/114 (30%), Positives = 53/114 (46%), Gaps = 21/114 (18%)
Frame = +1
Query: 202 VLDGVRYLHALGITHRDLKPENLLYYHPGTDSKIIITDFGLASAR------------KKG 249
++ G+ Y+H+LGI DL+P +L T + DFGL+ + G
Sbjct: 28 LVTGLHYIHSLGILFHDLRPSKVLL---DTSGVLKFADFGLSKVEGENLEELFFKFAEAG 198
Query: 250 DDC-------LMKT--TCGTPEYIAPEVLVRKPYTNSVDMWALGVIAYILLSGT 294
D +MK T G+P Y+APEV + D+WALG + Y + SG+
Sbjct: 199 DQWNIQSAEEMMKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSGS 360
>03508
Length = 1463
Score = 53.5 bits (127), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 30/99 (30%), Positives = 54/99 (54%), Gaps = 1/99 (1%)
Frame = +1
Query: 189 SFTERDATRVLQMVLDGVRYLHALGITHRDLKPENLLYYHPGTDSKIIITDFGLASARKK 248
+FT+ D L ++ + + H++GI HRD+KP N++ H + K+ + D+GLA
Sbjct: 859 TFTDYDIRFYLYELMKALDFCHSMGIMHRDVKPHNVMIDHE--NKKLRLIDWGLAEFYHP 1032
Query: 249 GDDCLMKTTCGTPEYIAPEVLV-RKPYTNSVDMWALGVI 286
G + + + PE+L+ + Y S+DMW+LG +
Sbjct: 1033GME--YNVRVASRYFKGPELLLDYQMYDYSLDMWSLGCM 1143
Score = 32.7 bits (73), Expect = 0.30, Method: Compositional matrix adjust.
Identities = 14/32 (43%), Positives = 21/32 (65%)
Frame = +2
Query: 324 VSNLAKDFIDRLLTVDPGARMTALQALRHPWV 355
+S A DF+D+LL D R+TA +A+ HP+
Sbjct: 1358 ISPEALDFLDKLLRYDHNERLTAREAMDHPYF 1453
>12786
Length = 460
Score = 53.5 bits (127), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 35/118 (29%), Positives = 57/118 (48%), Gaps = 21/118 (17%)
Frame = -3
Query: 202 VLDGVRYLHALGITHRDLKPENLLYYHPGTDSKIIITDFGLASARKKGDDCLMKTT-CGT 260
+L V+ LH G+ H DLKP N + + + DFG+A+ ++ ++K + GT
Sbjct: 383 MLRAVKALHNEGVIHSDLKPANFML----VAGNLKLIDFGIANTLQQDKTSVLKDSRVGT 216
Query: 261 PEYIAPEVLV-----------------RKP-YTNSV--DMWALGVIAYILLSGTMPFE 298
P Y++PE ++ KP Y V D+W+LG I Y ++ G PF+
Sbjct: 215 PSYMSPEAIMAACDDSADDSMEEDGHRTKPKYKVGVRSDVWSLGCILYNMVYGRTPFQ 42
>19301
Length = 712
Score = 51.2 bits (121), Expect = 8e-07, Method: Compositional matrix adjust.
Identities = 36/120 (30%), Positives = 59/120 (49%), Gaps = 8/120 (6%)
Frame = +2
Query: 130 ETKYREGREVCESELRVLRRVRHANIIQLVEVFETQERVYMVMELATGGELFDRIIAKGS 189
E ++ R++ E+++R LR++ H NII V ++ME G+L++ +
Sbjct: 380 EVAVKKVRDIKETDIRNLRKLNHPNIISFKGVCTQAPCYCIIMEYCPYGQLYEVL----- 544
Query: 190 FTERDATRV-LQMVLD-------GVRYLHALGITHRDLKPENLLYYHPGTDSKIIITDFG 241
RD + +VLD G+ YLH+ I HRDLK N+L + + I+DFG
Sbjct: 545 ---RDGKEIPPALVLDWSKQIASGMNYLHSHKIIHRDLKSPNVLV---AKNDVVKISDFG 706
>31489
Length = 329
Score = 50.1 bits (118), Expect = 2e-06, Method: Composition-based stats.
Identities = 26/88 (29%), Positives = 48/88 (54%), Gaps = 6/88 (6%)
Frame = +3
Query: 144 LRVLRRVRHANIIQLVEVFETQER------VYMVMELATGGELFDRIIAKGSFTERDATR 197
+++L+ +H NII + E+ + ++ +++V +L +L I + TE
Sbjct: 3 IKILKHFKHDNIISIREILKPKDSYHDFKDIHVVFDLMES-DLHRIIYSDQPLTEEHIRY 179
Query: 198 VLQMVLDGVRYLHALGITHRDLKPENLL 225
L +L G++Y+H+ + HRDLKP NLL
Sbjct: 180 FLYQILRGLKYIHSANVVHRDLKPSNLL 263
>28638
Length = 1458
Score = 49.3 bits (116), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 33/86 (38%), Positives = 47/86 (54%)
Frame = -1
Query: 212 LGITHRDLKPENLLYYHPGTDSKIIITDFGLASARKKGDDCLMKTTCGTPEYIAPEVLVR 271
+ I H DLKPEN+L +P S I I DFG S+ + G + + Y +PEVL+
Sbjct: 774 MNIIHCDLKPENILLCNPK-RSAIKIVDFG--SSCQLGQR--IYQYIQSRFYRSPEVLLG 610
Query: 272 KPYTNSVDMWALGVIAYILLSGTMPF 297
PY ++DMW+LG I + +G P
Sbjct: 609 VPYDLAIDMWSLGCILVEMHTGEPPL 532
Score = 37.7 bits (86), Expect = 0.010, Method: Compositional matrix adjust.
Identities = 34/133 (25%), Positives = 62/133 (46%), Gaps = 7/133 (5%)
Frame = -3
Query: 97 KYDIKALIGRGSFSRVVRVEHRATRQPYAIKMIETK--YREGREVCESELRVLRRVRHAN 154
+Y+I +LIG+GSF +VV+ ++ AIK+I+ K + ++ L ++ R N
Sbjct: 1144 RYEIDSLIGKGSFGQVVKAYDHGDQEQVAIKIIKNKKPFLNQAQIEVKLLELMNRHDADN 965
Query: 155 ---IIQLVEVFETQERVYMVMELATGG--ELFDRIIAKGSFTERDATRVLQMVLDGVRYL 209
I++L F + + +V EL + +L +G + D + + V+ G L
Sbjct: 964 XYYIVRLKRHFMFRNHLCLVFELLSYNLYDLLRNTNFRGGLPQLD-S*ICSAVVYGAAVL 788
Query: 210 HALGITHRDLKPE 222
G H L P+
Sbjct: 787 SHAGNEHYSL*PQ 749
>36481
Length = 806
Score = 49.3 bits (116), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 37/132 (28%), Positives = 67/132 (50%), Gaps = 10/132 (7%)
Frame = +2
Query: 105 GRGSFSRVVRVEHRATRQPYAIKMIET--KYREGREVCESELRVLRRVR----HAN--II 156
G G+F +VV+ + A+K+I+ KYRE ++ E+ VL ++R HA +
Sbjct: 389 GEGTFGKVVQCKDLLKGDDIALKIIKNVDKYREAAKL---EINVLEKLREKDPHAKHMCV 559
Query: 157 QLVEVFETQERVYMVMELATGGELFDRI--IAKGSFTERDATRVLQMVLDGVRYLHALGI 214
Q+++ F+ V + + G +FD + + G++ + + V +LH +
Sbjct: 560 QMLDWFDYHGHVCISFHML-GLSVFDFLKDNSYGAYPIEQVRHISYQLCYAVNFLHENQL 736
Query: 215 THRDLKPENLLY 226
TH DLKPEN+L+
Sbjct: 737 THTDLKPENILF 772
>26156
Length = 479
Score = 47.0 bits (110), Expect(2) = 4e-06, Method: Compositional matrix adjust.
Identities = 25/82 (30%), Positives = 51/82 (62%), Gaps = 4/82 (4%)
Frame = -1
Query: 103 LIGRGSFSRVVRVEHRATRQPYAIKMIETKY---REGREVCESELRVLRR-VRHANIIQL 158
+IGRGS+++V++VEH+ T++ YA+K+I+ + E + ++E V + ++ L
Sbjct: 368 VIGRGSYAKVLQVEHKRTKRIYAMKVIKKELVNDDEDIDWVQTEKHVFETATNYPFLVGL 189
Query: 159 VEVFETQERVYMVMELATGGEL 180
F+++ R++ V+E GG+L
Sbjct: 188 HSCFQSESRLFFVIEFVNGGDL 123
Score = 21.2 bits (43), Expect(2) = 4e-06, Method: Compositional matrix adjust.
Identities = 8/16 (50%), Positives = 11/16 (68%)
Frame = -3
Query: 205 GVRYLHALGITHRDLK 220
+ +LH GI +RDLK
Sbjct: 51 ALNFLHKRGIVYRDLK 4
>00715
Length = 1788
Score = 48.5 bits (114), Expect = 5e-06, Method: Compositional matrix adjust.
Identities = 51/214 (23%), Positives = 89/214 (41%), Gaps = 28/214 (13%)
Frame = +1
Query: 113 VRVEHRATRQPYAIKMIETKYREGREVCESELRVLR-RVRHANIIQLV---EVFETQERV 168
V++ H+ + P A+ R+ +EL R +RH N++ ++ + ++
Sbjct: 13 VKIYHKRSSNPRAL----------RQSYSNELLAFRCGLRHVNVVSILGATSLHRFEDGA 162
Query: 169 YMVMELATGGELFDRIIAKGSFTERDATRVLQMVLD---GVRYLHALGITHRDLKPENLL 225
++ ME G L + I + D++ L + L G+ YLH++ I H DLKP N L
Sbjct: 163 WLAMEYV--GPLNLQTILNDHQQDIDSSMRLSLALQMARGLHYLHSINIVHLDLKPANCL 336
Query: 226 YYHPGTDSKIIITDFG---------LASARKKG------------DDCLMKTTCGTPEYI 264
D K+ I DFG L ++G GT Y
Sbjct: 337 LTR---DLKLRIADFGCCHQLTPTGLDMGEREGGMAGNELELTPVQGAWKNELAGTLAYR 507
Query: 265 APEVLVRKPYTNSVDMWALGVIAYILLSGTMPFE 298
APE+L + D+++LG+ + + + P+E
Sbjct: 508 APELLKGLQPSVRSDVYSLGITLWQMCTRQGPYE 609
>31120
Length = 439
Score = 48.1 bits (113), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 30/90 (33%), Positives = 44/90 (48%), Gaps = 1/90 (1%)
Frame = +1
Query: 267 EVLVRKPYT-NSVDMWALGVIAYILLSGTMPFEDDNRTRLYRQILRGKYSYSGEPWPSVS 325
EV+ PY D W+LGVI +I+L+G MPF+D N +L KYS+ + VS
Sbjct: 1 EVVCGVPYDPKMADAWSLGVILFIMLNGKMPFDDSNLNKLLEDQRSKKYSFRRKLQDLVS 180
Query: 326 NLAKDFIDRLLTVDPGARMTALQALRHPWV 355
A+ + LL + R + L W+
Sbjct: 181 PNARSTVSVLLEPNSAMRWDLNEVLNCQWL 270
>32957
Length = 645
Score = 47.0 bits (110), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 20/38 (52%), Positives = 26/38 (68%)
Frame = +3
Query: 255 KTTCGTPEYIAPEVLVRKPYTNSVDMWALGVIAYILLS 292
+T CGT EY+APEV RK Y VD W LG++ + LL+
Sbjct: 39 RTFCGTREYMAPEVHERKEYGKEVDWWGLGILLHELLA 152
>36002
Length = 253
Score = 47.0 bits (110), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 21/58 (36%), Positives = 32/58 (55%)
Frame = +1
Query: 300 DNRTRLYRQILRGKYSYSGEPWPSVSNLAKDFIDRLLTVDPGARMTALQALRHPWVVS 357
D + L+ +I G Y + W ++S+ AKD I LL +P R +A L+HPWV +
Sbjct: 43 DCQELLFNRIQDGNYFFPSMEWSAISSSAKDLIRHLLVREPRKRYSAADVLKHPWVCN 216
>07940
Length = 1336
Score = 46.6 bits (109), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 35/111 (31%), Positives = 53/111 (47%), Gaps = 3/111 (2%)
Frame = -3
Query: 190 FTERDATRVLQMVLDGVRYLHALGITHRDLKPENLLYYHPGTDSKIIITDFGLASARKKG 249
T +D V G+ YL + HRDL N+L + + I DFGL ++
Sbjct: 356 LTPKDLISYAYQVARGMEYLASKQCIHRDLAARNVLV---AEEYVLKIADFGLTRNLQQF 186
Query: 250 DDCLMKTTCGT--PEYIAPEVLVRKPYTNSVDMWALGVIAY-ILLSGTMPF 297
D KTT G +++APE L + YT+ D+W+ GV+ + I G P+
Sbjct: 185 D-YYRKTTDGRLPVKWMAPEALFDRKYTSKSDVWSYGVLLWEIFTLGGNPY 36
>04138
Length = 800
Score = 45.8 bits (107), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 51/189 (26%), Positives = 76/189 (40%), Gaps = 41/189 (21%)
Frame = +1
Query: 208 YLHALGITHRDLKPENLLYYHPGTDSKIIITDFGLASARKKGDDCLMKTT--CGTPEYIA 265
Y+H I HRD+K N+L G + + DFGLA A + T T Y
Sbjct: 58 YIHRNKILHRDMKAANILITKQGV---LKLADFGLARAFSVNLRQPNRYTNRVVTLWYRP 228
Query: 266 PEVLV-RKPYTNSVDMWALGVIAYIL------LSGTMPFEDDNRTRLYRQILRGKYSYSG 318
PE+L+ + Y+ ++D W G I + + GT + N+ L Q+ S +
Sbjct: 229 PELLLGDRNYSTAIDQWGAGCIMAEMWTRNPIMQGT---TEQNQLTLITQLCG---SITP 390
Query: 319 EPWPSVSNLAK------------------------------DFIDRLLTVDPGARMTALQ 348
E WP V+ L+ D +RLL +DP R++A +
Sbjct: 391 EVWPGVTQLSMYHQIKGALAAGRKNIIRDRFARILKDPYGLDLFERLLKMDPSQRISADE 570
Query: 349 ALRHP--WV 355
AL H WV
Sbjct: 571 ALNHDFFWV 597
>37602
Length = 804
Score = 45.8 bits (107), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 31/98 (31%), Positives = 46/98 (46%), Gaps = 3/98 (3%)
Frame = -1
Query: 151 RHANIIQLVEVFET---QERVYMVMELATGGELFDRIIAKGSFTERDATRVLQMVLDGVR 207
R NI V F++ +E++++ ME GG + D G TE V + L G+
Sbjct: 354 RIVNIQTFVGYFDSYLRREKLWIAMEYCGGGSMQDIYHVTGPLTEPQIAFVCRETLKGLH 175
Query: 208 YLHALGITHRDLKPENLLYYHPGTDSKIIITDFGLASA 245
YLH G HRD+K N+L G + + DF S+
Sbjct: 174 YLHRRGKMHRDIKGANILLTEEG---DVKLADFWRVSS 70
>07291
Length = 833
Score = 45.1 bits (105), Expect = 5e-05, Method: Compositional matrix adjust.
Identities = 28/117 (23%), Positives = 56/117 (47%), Gaps = 6/117 (5%)
Frame = +1
Query: 202 VLDGVRYLHALGITHRDLKPENLLYYHPGTDSKIIITDFGLA-----SARKKGDDCLMKT 256
+ DG+ YL + + HR+L N + D ++ ++D+G+ + DD +
Sbjct: 76 IADGMAYLQEVKVVHRNLAARNCIVTE---DGRLQLSDYGVTGSLFPQSYYTADDSPARD 246
Query: 257 TCGTPEYIAPEVLVRKPYTNSVDMWALGVIAYILLS-GTMPFEDDNRTRLYRQILRG 312
+++APE + +++ D+WA GV+ + LL+ G P+ D + L + G
Sbjct: 247 LV---KWMAPETIDNFHFSSKSDVWAFGVVLWELLTRGITPYPDVENSSLLPYLKEG 408
>07833
Length = 1504
Score = 44.7 bits (104), Expect = 8e-05, Method: Compositional matrix adjust.
Identities = 37/162 (22%), Positives = 71/162 (43%), Gaps = 9/162 (5%)
Frame = -3
Query: 147 LRRVRHANIIQLVEVFETQERVYMVMELATGGELFDRIIAKGSFTERDATRVLQMVLD-- 204
LR H N++ ++ + ++ + G L++ + + D + L+ +D
Sbjct: 1457 LRIFNHPNVLPVLACCNQPPNLVLISQFMPFGSLYNTLHGESGIV-VDQNQSLRFAMDIA 1281
Query: 205 -GVRYLHALGITHRDLKPENLLYYHPGTDSKIIITDFGLASARKKGDDCLM---KTTCGT 260
G+ +LH++ T P LL SK ++ D L + D C K +
Sbjct: 1280 RGMEFLHSMEPT----IPNFLL------TSKHVMIDEDLTARINMADYCFSFHEKGKVYS 1131
Query: 261 PEYIAPEVLVRKP---YTNSVDMWALGVIAYILLSGTMPFED 299
P ++APE L R+P T + DMW+ ++ + L + +PF +
Sbjct: 1130 PAWMAPEALQRRPDDINTRAADMWSFAILMWELETREVPFAE 1005
>01106
Length = 878
Score = 44.3 bits (103), Expect = 9e-05, Method: Compositional matrix adjust.
Identities = 44/173 (25%), Positives = 77/173 (44%), Gaps = 16/173 (9%)
Frame = +3
Query: 69 GHTEPPSEPPRRARVAKYR-AKFDPRVTAKYDIKALIGRGSFSRVVRVEHRATRQPYAIK 127
G + E PR Y K +Y + +G G FS V ++ A+K
Sbjct: 234 GSDDDEQEDPRDYCKGGYHPVKNGDLFNGRYHVIRKLGWGHFSTVWLCWDLTCKRFVALK 413
Query: 128 MIETKYREGREVCESELRVLRRVRHANI--------IQLVEVFETQ----ERVYMVMELA 175
++++ + E E+++L+ VR +++ +QL++ F+ V MV E+
Sbjct: 414 VVKSA-QHYTETALDEVKLLKCVRESDVADPARAKCVQLLDDFKISGVNGTHVAMVFEV- 587
Query: 176 TGGELFDRIIAKG--SFTERDATRVLQMVLDGVRYLHA-LGITHRDLKPENLL 225
G L II + +++ VL+G+ Y+HA I H D+KPEN+L
Sbjct: 588 LGYNLLKLIIRSNYQGIPIHNVKLIIRQVLEGLSYMHAKCRIIHTDIKPENIL 746
>11404
Length = 563
Score = 44.3 bits (103), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 40/139 (28%), Positives = 70/139 (50%), Gaps = 10/139 (7%)
Frame = +1
Query: 97 KYDIKALIGRGSFSRVVRVEHRATRQPYAIKMIETK--YREGREVCESELRVLRRVRHAN 154
+Y+I +LIG+GSF +VV+ + AIK+I+ K + ++ L ++ R N
Sbjct: 142 RYEIDSLIGKGSFGQVVKAYDHTDNEQVAIKIIKNKKPFLNQAQIEVKLLEMMNRHDTDN 321
Query: 155 ---IIQLVEVFETQERVYMVMELATGGELFDRIIAKGSF--TERDATRVL-QMVLDGVRY 208
I++L F + + +V EL + L+D ++ +F + TR Q + + +
Sbjct: 322 KYYIVRLKRHFMFRSHLCLVFELLSYN-LYD-LLRNTNFRGVSLNLTRKFAQQLCTALLF 495
Query: 209 LHA--LGITHRDLKPENLL 225
L + I H DLKPEN+L
Sbjct: 496 LATPEMSIIHCDLKPENIL 552
>21418
Length = 831
Score = 43.5 bits (101), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 19/56 (33%), Positives = 29/56 (51%)
Frame = +2
Query: 305 LYRQILRGKYSYSGEPWPSVSNLAKDFIDRLLTVDPGARMTALQALRHPWVVSMAA 360
+ ++I G+Y + W +VS AKD I +L VDP R+ LR+ W+ A
Sbjct: 2 MKKRIRSGQYDFPDPEWTNVSQAAKDLIKGMLNVDPSKRLCIEDVLRNKWIAQYDA 169
>17300
Length = 480
Score = 42.7 bits (99), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 29/118 (24%), Positives = 58/118 (49%), Gaps = 7/118 (5%)
Frame = +1
Query: 202 VLDGVRYLHALGITHRDLKPENLLYYHPGTDSKIII---TDFGLASARKKGDDCLMKTTC 258
+ G+ L +G HRDL N+L ++I++ DFGL+ + TT
Sbjct: 1 ISSGMGXLADMGYVHRDLAARNILV------NEILVCKVADFGLSREIESDTTEGAYTTK 162
Query: 259 GTP---EYIAPEVLVRKPYTNSVDMWALGVIAYILLS-GTMPFEDDNRTRLYRQILRG 312
G + APE + + +T++ D+W+ GV+ + ++S G P+ + + + + + +G
Sbjct: 163 GGKIPVRWTAPEAIAYRKFTSASDVWSFGVVMWEVMSYGERPYWNWSNQDVIKAVEKG 336
>37063
Length = 455
Score = 42.4 bits (98), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 30/82 (36%), Positives = 40/82 (48%), Gaps = 9/82 (10%)
Frame = -2
Query: 219 LKPENLLYYHPGTDSKIIITDFGLASARKKGDDCL----MKTTCGTPEYIAPEVL----- 269
LKPEN+L H + I DF LAS D + T G+ EY+APEV+
Sbjct: 454 LKPENILCEHLDEVVPLKICDFDLASGINCDGDGTKTPELLTPVGSAEYMAPEVVDAWVG 275
Query: 270 VRKPYTNSVDMWALGVIAYILL 291
Y DMW+LG+I +L+
Sbjct: 274 ESFSYDKRCDMWSLGIIL*VLV 209
>18401
Length = 463
Score = 42.0 bits (97), Expect = 5e-04, Method: Compositional matrix adjust.
Identities = 33/141 (23%), Positives = 60/141 (42%), Gaps = 41/141 (29%)
Frame = -3
Query: 256 TTCGTPEYIAPEVLVRKPYTNSVDMWALGVIAYILLSGTMPFE-DDNRT----------- 303
T T Y APEV++ +++ D+W++G I + L +G F+ DN+
Sbjct: 455 TIVSTRHYRAPEVILELGWSHPCDVWSVGCIMFELYTGYTLFQTHDNKEHLAMMERILGS 276
Query: 304 ---RLYRQILRGKYSYSGE-PWPSVSNLAK-------------------------DFIDR 334
R+ ++ + KY + G P S++A+ D + +
Sbjct: 275 LPYRMAKKTKKQKYFHHGRLDVPERSSMARYVRENTKPLLRYVKDRENKDHQQLFDLMKK 96
Query: 335 LLTVDPGARMTALQALRHPWV 355
LL + +R + LQAL+HP+
Sbjct: 95 LLAYEASSRYSLLQALQHPFF 33
>23319
Length = 2235
Score = 40.8 bits (94), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 31/123 (25%), Positives = 52/123 (42%), Gaps = 30/123 (24%)
Frame = +3
Query: 266 PEVLVRKPYTNSVDMWALGVIAYILLSGTMPF-----EDDNRTRLYRQILRGKYSYSGEP 320
P+V K Y+ S+DMW+ G I L + P +DD R+++ L G + + +
Sbjct: 3 PDVYXAKMYSTSIDMWSAGCIFAELANAGRPLFPGNDDDDQLKRIFK--LLG--TPTEDQ 170
Query: 321 WPSVSNL-------------------------AKDFIDRLLTVDPGARMTALQALRHPWV 355
WP ++ L +D + LL P RM+A +AL+HP+
Sbjct: 171 WPGMTQLPNYRMFPMYHVTTTWQQVVPKLNSKGRDLLQCLLVCCPSDRMSADEALQHPYF 350
Query: 356 VSM 358
+
Sbjct: 351 ADL 359
>14116
Length = 1017
Score = 40.8 bits (94), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 48/200 (24%), Positives = 83/200 (41%), Gaps = 11/200 (5%)
Frame = -1
Query: 104 IGRGSFSRVVRVEHRATRQPYAIKMIETKYREGREVCESELR-------VLRRVRHANII 156
IG+G+F V R Q I ++ K E EL+ +++ H+N++
Sbjct: 612 IGKGNFGCVKRGFLTLPEQKGDI-LVAVKTLHNNNPREIELQSFLQEALIMKDFHHSNVL 436
Query: 157 QLVEV-FETQERVYMVMELATGGELFDRI-IAKGSFTERDATRVLQMVLDGVRYLHALGI 214
L+ + + +V+ G+L I + T +D + G+ YL L
Sbjct: 435 TLIGICLNLDDMPLVVLPFMKHGDLLTYIRDDQHQPTIKDLIMYGVDIARGMDYLAGLKF 256
Query: 215 THRDLKPENLLYYHPGTDSKIIITDFGLASA--RKKGDDCLMKTTCGTPEYIAPEVLVRK 272
HRDL N + D + + DFGLA K+ K +++A E L +
Sbjct: 255 VHRDLAARNCML---DEDFHVKVADFGLARDIYEKEYYSSENKKAKLPVKWMALESLEKG 85
Query: 273 PYTNSVDMWALGVIAYILLS 292
Y + D+W+ GV+ + LL+
Sbjct: 84 NYDSKTDVWSYGVVLWELLT 25
>07836
Length = 1478
Score = 40.0 bits (92), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 42/172 (24%), Positives = 74/172 (43%), Gaps = 24/172 (13%)
Frame = -1
Query: 141 ESELRVLRRVRHANIIQLVEV----FETQERVYMVMELATGGELFDRIIAKGSFTERDAT 196
E+EL +RH NI+ + + +++++ + G L D ++++ D++
Sbjct: 1421 ETELYQTVLLRHENILGFIAADIKGTGSWTQLFLITDYHENGSLHDYLLSR----VLDSS 1254
Query: 197 RVLQMV---LDGVRYLHAL--------GITHRDLKPENLLYYHPGTDSKIIITDFGLAS- 244
+L + + G+ +LH I HRD+K +N+L GT I D GLA
Sbjct: 1253 EMLALAHSAICGLAHLHIEIFGTRGKPAIAHRDIKSKNILVKKNGT---CCIADLGLAVR 1083
Query: 245 --ARKKGDDCLMKTTCGTPEYIAPEVLVRKPYTNS------VDMWALGVIAY 288
+ D GT Y+APEVL + DM+A G++ +
Sbjct: 1082 YISESNEVDVAPNPRQGTKRYMAPEVLEMLLNVKNFDAFKQADMYAFGLVMW 927
>02638
Length = 1490
Score = 40.0 bits (92), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 26/96 (27%), Positives = 45/96 (46%), Gaps = 1/96 (1%)
Frame = +1
Query: 259 GTPEYIAPEVLVRKPYTNSVDMWALGVIAYILLSGTMPFEDDNRTRLYRQILRGKYSYSG 318
GT ++APEVL + Y + D+W++G + + + P+ + + I + S
Sbjct: 22 GTIAFMAPEVLRGESYGRACDVWSVGCVMIEMCTCRPPWNSHDISNHLALIFKIASSVDP 201
Query: 319 EPWP-SVSNLAKDFIDRLLTVDPGARMTALQALRHP 353
P P ++S +D + R L D R +A L HP
Sbjct: 202 PPIPENMSPPVRDLMLRCLEQDSDFRPSAKDLLMHP 309
>18481
Length = 437
Score = 40.0 bits (92), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 28/80 (35%), Positives = 40/80 (50%), Gaps = 2/80 (2%)
Frame = -1
Query: 170 MVMELA--TGGELFDRIIAKGSFTERDATRVLQMVLDGVRYLHALGITHRDLKPENLLYY 227
+VMEL + ELF +I K FT + V +L + ++H HRDLKP+N L
Sbjct: 266 LVMELLGPSLEELF--VICKRRFTLKTILMVSDQLLSRLEFIHQKCFIHRDLKPDNFLMG 93
Query: 228 HPGTDSKIIITDFGLASARK 247
++ I DFGL+ K
Sbjct: 92 LGRHCHRLYIIDFGLSKRYK 33
>29360
Length = 363
Score = 38.9 bits (89), Expect = 0.004, Method: Composition-based stats.
Identities = 30/116 (25%), Positives = 56/116 (48%), Gaps = 8/116 (6%)
Frame = +3
Query: 118 RATRQPYAIKMIETKYREGREVCESELRVLRRVRHA-----NIIQLVEVFETQERVYMVM 172
+ T + AIK+++ R+ + E+ +L+R+ N ++ E F+ + +V
Sbjct: 18 KGTSEIVAIKILKNHPSYARQ-GQIEVSILQRLSQESADDYNFVRAFECFQHKNHTCLVF 194
Query: 173 ELATGGELFDRIIAKGSFTE---RDATRVLQMVLDGVRYLHALGITHRDLKPENLL 225
E+ L+D + + F + + Q VL +R L LG+ H DLKPEN++
Sbjct: 195 EMLEQ-NLYD-FLKQNKFQPLPLKYIRPITQQVLTALRKLKQLGLIHADLKPENIM 356
>20655
Length = 1181
Score = 37.4 bits (85), Expect = 0.011, Method: Compositional matrix adjust.
Identities = 17/51 (33%), Positives = 25/51 (49%)
Frame = +2
Query: 305 LYRQILRGKYSYSGEPWPSVSNLAKDFIDRLLTVDPGARMTALQALRHPWV 355
+ ++I G+Y + W VS AKD I +L DP R+ Q + WV
Sbjct: 2 MKKRIRNGQYEFPKPEWSRVSQDAKDLIRGMLCTDPDKRLNIKQVMASKWV 154
>21800
Length = 855
Score = 37.4 bits (85), Expect = 0.011, Method: Compositional matrix adjust.
Identities = 31/103 (30%), Positives = 51/103 (49%), Gaps = 15/103 (14%)
Frame = +2
Query: 138 EVCESELRVLRRVRHAN--------IIQLVEVFETQ----ERVYMVMELATGGELFDRII 185
E E+++L+ VR+++ +QL++ F+ V MV E+ G L II
Sbjct: 428 ETALDEIKLLKCVRNSDETDPAREKSVQLLDDFKISGVNGTHVCMVFEV-LGYNLLKLII 604
Query: 186 AKG--SFTERDATRVLQMVLDGVRYLHA-LGITHRDLKPENLL 225
+ +++ VL+G+ YLHA I H D+KPEN+L
Sbjct: 605 RSNYQGIPVHNVKLIIRQVLEGLNYLHAKCNIIHTDIKPENIL 733
>12672
Length = 773
Score = 37.4 bits (85), Expect = 0.013, Method: Compositional matrix adjust.
Identities = 25/102 (24%), Positives = 50/102 (49%), Gaps = 5/102 (4%)
Frame = +3
Query: 197 RVLQMVLDGVRYLHALGITHRDLKPENLLYYHPGTDSKII--ITDFGLASARKKGDDCLM 254
++++ G++YL+ G HRD+K N+L DS+ + DF + G+ +
Sbjct: 3 KIVKGTASGIQYLNDNGHVHRDIKTANILL-----DSEYTAKVGDFATVVSAPSGEGKTV 167
Query: 255 KT---TCGTPEYIAPEVLVRKPYTNSVDMWALGVIAYILLSG 293
+ GT Y+APE + + +D ++ GV+ +++G
Sbjct: 168 QNASVVIGTAAYLAPEA-IHFDVSTKLDSYSFGVVLLEVITG 290
>33586
Length = 551
Score = 36.2 bits (82), Expect = 0.027, Method: Compositional matrix adjust.
Identities = 15/41 (36%), Positives = 26/41 (63%)
Frame = +2
Query: 155 IIQLVEVFETQERVYMVMELATGGELFDRIIAKGSFTERDA 195
I+ L F+T+ ++Y+++E GG+LF R+ + FTE D
Sbjct: 407 IVHLHYAFQTEGKLYLILEFLRGGDLFTRLSKEVMFTEEDV 529
>16350
Length = 1108
Score = 35.8 bits (81), Expect = 0.031, Method: Compositional matrix adjust.
Identities = 17/48 (35%), Positives = 26/48 (54%)
Frame = +3
Query: 308 QILRGKYSYSGEPWPSVSNLAKDFIDRLLTVDPGARMTALQALRHPWV 355
++L KY + P + DF+ +L DP R TA Q+L+HPW+
Sbjct: 708 EVLVEKYEWD----PKDAKAFADFLAPMLEFDPEQRATAAQSLQHPWL 839
>17722
Length = 680
Score = 35.8 bits (81), Expect = 0.035, Method: Compositional matrix adjust.
Identities = 20/72 (27%), Positives = 34/72 (47%)
Frame = -3
Query: 278 VDMWALGVIAYILLSGTMPFEDDNRTRLYRQILRGKYSYSGEPWPSVSNLAKDFIDRLLT 337
VD W GV+ Y ++ G +PF + + L+ IL + ++S AK + LL
Sbjct: 678 VDWWGTGVVMYEMMCGRLPFYNRDHDVLFELILLQNVKFPR----NLSEEAKTLLSGLLA 511
Query: 338 VDPGARMTALQA 349
+P R+ +A
Sbjct: 510 KNPKRRLGGSEA 475
>20513
Length = 405
Score = 35.0 bits (79), Expect = 0.058, Method: Composition-based stats.
Identities = 17/48 (35%), Positives = 26/48 (54%)
Frame = -1
Query: 308 QILRGKYSYSGEPWPSVSNLAKDFIDRLLTVDPGARMTALQALRHPWV 355
++L KY + P + DF+ +L DP R TA Q+L+HPW+
Sbjct: 336 EVLVEKYEWD----PKDAKAFADFLAPMLEFDPEQRATAAQSLQHPWL 205
>17516
Length = 453
Score = 33.5 bits (75), Expect = 0.16, Method: Compositional matrix adjust.
Identities = 17/39 (43%), Positives = 25/39 (64%), Gaps = 1/39 (2%)
Frame = -3
Query: 256 TTCGTPEYIAPEVLVRK-PYTNSVDMWALGVIAYILLSG 293
T GTP Y+APEVL++K Y D+++L +I + L G
Sbjct: 442 TLAGTPVYMAPEVLLQKGQYDMKADVYSLAIILWELWYG 326
>03294
Length = 1684
Score = 33.1 bits (74), Expect = 0.19, Method: Compositional matrix adjust.
Identities = 24/109 (22%), Positives = 45/109 (41%), Gaps = 25/109 (22%)
Frame = -1
Query: 278 VDMWALGVIAYILLSGTMPFEDDNRTRLYRQILRGKYSYSGEPWP--------------- 322
VD+W++G I +L T F+ D+ +I R + + + WP
Sbjct: 1672 VDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKLPAFNGMFPLW 1493
Query: 323 ----------SVSNLAKDFIDRLLTVDPGARMTALQALRHPWVVSMAAS 361
+ +L D I+R L DP R++ + L+H + +++ S
Sbjct: 1492 KEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYFLNVDTS 1346
>17932
Length = 597
Score = 33.1 bits (74), Expect = 0.23, Method: Compositional matrix adjust.
Identities = 15/35 (42%), Positives = 21/35 (60%), Gaps = 2/35 (5%)
Frame = -2
Query: 281 WALGVIAYILLSGTMPFEDDNRTRL--YRQILRGK 313
W+LGV AY +L G PF DD+ + + Y I+ K
Sbjct: 593 WSLGVCAYEMLFGCTPFTDDDGSMVATYNNIMNYK 489
>00638
Length = 1595
Score = 31.6 bits (70), Expect = 0.61, Method: Compositional matrix adjust.
Identities = 12/33 (36%), Positives = 21/33 (63%)
Frame = +2
Query: 189 SFTERDATRVLQMVLDGVRYLHALGITHRDLKP 221
+FT+ D L ++ + + H++GI HRD+KP
Sbjct: 404 TFTDYDIRFYLYELMKALDFCHSMGIMHRDVKP 502
>18996
Length = 491
Score = 31.6 bits (70), Expect = 0.62, Method: Compositional matrix adjust.
Identities = 23/83 (27%), Positives = 39/83 (46%), Gaps = 2/83 (2%)
Frame = +2
Query: 216 HRDLKPENLLYYHPGTDSKIIITDFGLASARKKGDDCLMKTTCGTP-EYIAPEVLVRKPY 274
HRDL N+L S + I+DFGLA + P ++ +PE + +
Sbjct: 5 HRDLAARNILV----DRSCVKISDFGLAQFANADGYYYGISQRDIPIKWYSPEAIETCKF 172
Query: 275 TNSVDMWALGVIAYILLS-GTMP 296
++ D+W+ GV + + S G +P
Sbjct: 173 SSYSDVWSYGVTLFEMFSRGEIP 241
>13305
Length = 549
Score = 30.0 bits (66), Expect = 1.6, Method: Compositional matrix adjust.
Identities = 13/45 (28%), Positives = 23/45 (51%), Gaps = 1/45 (2%)
Frame = +2
Query: 263 YIAPEVLVRKPYTNSVDMWALGVIAY-ILLSGTMPFEDDNRTRLY 306
++A E L YT D+W+ GV+ + I G P+ + +L+
Sbjct: 23 WMAVESLFNNTYTTQSDVWSFGVVLWEIFTLGGTPYSSTDTQQLF 157
>35032
Length = 465
Score = 30.0 bits (66), Expect = 1.7, Method: Compositional matrix adjust.
Identities = 12/26 (46%), Positives = 16/26 (61%)
Frame = +3
Query: 330 DFIDRLLTVDPGARMTALQALRHPWV 355
D + RLL DP R+T AL HP++
Sbjct: 147 DLVKRLLNYDPSKRLTPXXALAHPFL 224
>22005
Length = 873
Score = 30.0 bits (66), Expect = 1.9, Method: Compositional matrix adjust.
Identities = 24/107 (22%), Positives = 42/107 (39%), Gaps = 1/107 (0%)
Frame = +1
Query: 186 AKGSFTERDATRVLQMVLDGVRYLHALGITHRDLKPENLLYYHPGTDSKIIITDFGLASA 245
G +D + Q + G+ YL HRDL + I+DFGLA +
Sbjct: 421 CSGMLXTKDQLYISQQISAGMAYLAQKDYVHRDLATRT----VXSRTT*S*ISDFGLARS 588
Query: 246 RKKGDDCLMKTTCGTP-EYIAPEVLVRKPYTNSVDMWALGVIAYILL 291
D P ++ E ++ ++ D+W+ GV+ + +L
Sbjct: 589 VHSVDYYRGSEQDAIPIRWMPLEAILYSKFSTQSDVWSFGVVLWEIL 729
>20773
Length = 391
Score = 30.0 bits (66), Expect = 2.0, Method: Compositional matrix adjust.
Identities = 13/26 (50%), Positives = 17/26 (65%)
Frame = -1
Query: 330 DFIDRLLTVDPGARMTALQALRHPWV 355
+ + RLLT DP R+T AL HP+V
Sbjct: 304 NLVQRLLTYDPSQRLTPDLALSHPFV 227
>14104
Length = 573
Score = 29.6 bits (65), Expect = 2.1, Method: Compositional matrix adjust.
Identities = 11/28 (39%), Positives = 17/28 (60%)
Frame = +1
Query: 328 AKDFIDRLLTVDPGARMTALQALRHPWV 355
A F+ L +DP R+T Q L+HP++
Sbjct: 100 AMSFMQSCLKMDPAERLTCHQLLQHPYM 183
>17644
Length = 463
Score = 29.6 bits (65), Expect = 2.2, Method: Compositional matrix adjust.
Identities = 13/25 (52%), Positives = 16/25 (64%)
Frame = +3
Query: 331 FIDRLLTVDPGARMTALQALRHPWV 355
+ RLLT DP R+T AL HP+V
Sbjct: 90 LVQRLLTYDPSQRLTPDLALSHPFV 164
>16708
Length = 1397
Score = 29.6 bits (65), Expect = 2.5, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%)
Frame = -1
Query: 206 VRYLHALGITHRDLKPENLLYYHPGTDSKIIITDFGLASARK 247
+ ++H LG+ H D+K +N+L G +TD+G+A K
Sbjct: 1055 LEHIHELGVVHMDVKADNVLVDAHG---NCKLTDYGIAQLYK 939
>12517
Length = 1242
Score = 29.3 bits (64), Expect = 3.5, Method: Compositional matrix adjust.
Identities = 13/42 (30%), Positives = 24/42 (57%)
Frame = +3
Query: 327 LAKDFIDRLLTVDPGARMTALQALRHPWVVSMAASSSMKNLH 368
L + I +++ R+++L A+R W+V A SMK++H
Sbjct: 447 LIRKLIVHIMSFGFTLRVSSLSAIRCGWIVLNAEEKSMKSMH 572
>15549
Length = 470
Score = 28.9 bits (63), Expect = 4.7, Method: Compositional matrix adjust.
Identities = 12/42 (28%), Positives = 23/42 (54%)
Frame = -1
Query: 88 AKFDPRVTAKYDIKALIGRGSFSRVVRVEHRATRQPYAIKMI 129
A+F R +++ +G+G + V R +++ Q YA+K I
Sbjct: 242 AEFKSRFADEFECIEQMGKGGYGIVFRAKNKVDEQEYAVKRI 117
>21210
Length = 518
Score = 28.5 bits (62), Expect = 5.2, Method: Compositional matrix adjust.
Identities = 27/107 (25%), Positives = 49/107 (45%), Gaps = 10/107 (9%)
Frame = +3
Query: 259 GTPEYIAPEVLVRKP----YTNSVDMWALGVIAYILLSGTMPFEDDNRTRLY---RQILR 311
G Y+APE + + Y D+W+LG+ L +G P+ ++ +Q++R
Sbjct: 6 GCRPYMAPERIDPRASSHGYDVRSDVWSLGITLMELATGRFPYR--KWVSIFDQLQQVVR 179
Query: 312 GK---YSYSGEPWPSVSNLAKDFIDRLLTVDPGARMTALQALRHPWV 355
G + G + S+ +F+++ LT D R + L HP+V
Sbjct: 180 GVAPCLPHDG----AFSHDFVNFVNKCLTKDEKQRPKYNKLLAHPFV 308
>26909
Length = 394
Score = 28.5 bits (62), Expect = 5.6, Method: Composition-based stats.
Identities = 12/33 (36%), Positives = 21/33 (63%)
Frame = +2
Query: 331 FIDRLLTVDPGARMTALQALRHPWVVSMAASSS 363
+ +LLT+DP R+T+ QA++ P+ + SS
Sbjct: 266 LLQKLLTMDPVKRITSEQAMKDPYFLEEPLPSS 364
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000296509 | hsapiens_gene_ensembl | Mitotic
spindle assembly checkpoint protein MAD2A (MAD2-like 1) (HsMAD2).
[Source:Uniprot/SWISSPROT;Acc:Q13257]
(205 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
28145 177 2e-50
26223 29 1.3
34102 27 4.2
>28145
Length = 524
Score = 177 bits (448), Expect(2) = 2e-50, Method: Compositional matrix adjust.
Identities = 87/152 (57%), Positives = 113/152 (74%)
Frame = -2
Query: 23 FFSFGINSILYQRGIYPSETFTRVQKYGLTLLVTTDLELIKYLNNVVEQLKDWLYKCSVQ 82
FF+ + + P ++FT Q+YGLTLLVTT+ EL+KYL V+ +K WL + VQ
Sbjct: 505 FFTMVSTASCIREASTP-QSFTHQQQYGLTLLVTTNGELVKYLKTVIAXVKSWLQELIVQ 329
Query: 83 KLVVVISNIESGEVLERWQFDIECDKTAKDDSAPREKSQKAIQDEIRSVIRQITATVTFL 142
KLV+VI +++ EV+ERWQFDI+CDKTA DD R+K++K +++EI+S+IRQITATVTFL
Sbjct: 328 KLVLVIKQVDTNEVVERWQFDIQCDKTA-DDKTKRDKTEKEVREEIKSIIRQITATVTFL 152
Query: 143 PLLEVSCSFDLLIYTDKDLVVPEKWEESGPQF 174
PLLE CSFD+LIYTDKD VP W ESGP F
Sbjct: 151 PLLESVCSFDVLIYTDKDAEVPTNWGESGPHF 56
Score = 39.3 bits (90), Expect(2) = 2e-50, Method: Compositional matrix adjust.
Identities = 18/19 (94%), Positives = 18/19 (94%)
Frame = -3
Query: 174 FITNSEEVRLRSFTTTIHK 192
FI NSEEVRLRSFTTTIHK
Sbjct: 57 FIANSEEVRLRSFTTTIHK 1
Score = 47.8 bits (112), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 20/26 (76%), Positives = 23/26 (88%)
Frame = -1
Query: 19 IVAEFFSFGINSILYQRGIYPSETFT 44
IVAEFF +GINSILYQRGIYP E ++
Sbjct: 518 IVAEFFHYGINSILYQRGIYPPELYS 441
>26223
Length = 410
Score = 29.3 bits (64), Expect = 1.3, Method: Compositional matrix adjust.
Identities = 20/68 (29%), Positives = 39/68 (57%)
Frame = +3
Query: 37 IYPSETFTRVQKYGLTLLVTTDLELIKYLNNVVEQLKDWLYKCSVQKLVVVISNIESGEV 96
IYP F R +KY + + V ++ +Y+++V ++ + V+++ VV+ + S +
Sbjct: 3 IYPQGVFVRKRKYNIPVQVCLHPDVKQYVSSVCSSMRTLFLQGVVRRVDVVLLSPGS-QP 179
Query: 97 LERWQFDI 104
LER+ FDI
Sbjct: 180 LERFVFDI 203
>34102
Length = 734
Score = 27.3 bits (59), Expect = 4.2, Method: Compositional matrix adjust.
Identities = 11/37 (29%), Positives = 22/37 (59%)
Frame = -2
Query: 72 LKDWLYKCSVQKLVVVISNIESGEVLERWQFDIECDK 108
L + CS++K V+ N+ S +++R +F + CD+
Sbjct: 454 LARSIVNCSLKKNVIARKNVMSSLLVKRCRFLVACDR 344
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000321800 | hsapiens_gene_ensembl | Fizzy-related
protein homolog (Fzr) (Cdh1/Hct1 homolog) (hCDH1) (CDC20-like protein
1). [Source:Uniprot/SWISSPROT;Acc:Q9UM11]
(404 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
14500 155 2e-50
34005 124 1e-31
29912 132 2e-31
00561 57 2e-11
27760 65 7e-11
02147 60 2e-09
13335 57 1e-08
01327 57 1e-08
30256 56 2e-08
19498 55 4e-08
17598 55 6e-08
03156 54 1e-07
27465 53 2e-07
12806 51 9e-07
16389 50 1e-06
17266 50 2e-06
03387 50 2e-06
19949 50 2e-06
16105 48 6e-06
02960 46 2e-05
12574 45 5e-05
01598 45 6e-05
01805 44 1e-04
01249 44 2e-04
15780 42 6e-04
31474 40 0.001
30295 40 0.002
14555 39 0.003
10264 39 0.006
01768 38 0.008
27475 37 0.010
19863 37 0.018
18981 36 0.025
13278 36 0.031
02090 36 0.032
26107 35 0.037
01462 35 0.041
37142 35 0.057
31054 35 0.068
12140 35 0.078
21921 34 0.12
34511 33 0.16
21105 33 0.23
19140 33 0.24
15337 33 0.27
15118 33 0.30
15972 33 0.30
01584 32 0.33
36111 32 0.35
21025 32 0.38
11493 31 0.74
27270 31 0.90
27681 31 0.93
10162 31 0.99
07665 31 1.1
28289 29 2.7
16199 29 3.8
30679 29 4.0
12841 28 4.5
17602 28 4.7
00105 28 4.8
30297 28 5.2
30108 28 5.3
38177 28 5.9
31500 27 9.9
>14500
Length = 1238
Score = 155 bits (392), Expect(2) = 2e-50, Method: Compositional matrix adjust.
Identities = 69/118 (58%), Positives = 89/118 (75%)
Frame = +3
Query: 274 WSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNLAWSKHANELVSTHGYSQ 333
W P Q LLASGGGTADR I FWN TG L +DT SQVC L WSK EL+S+HG++Q
Sbjct: 225 WCPWQPSLLASGGGTADRHIHFWNCNTGTNLSSVDTKSQVCALLWSKEHRELISSHGFAQ 404
Query: 334 NQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKTRSTK 391
NQ+++WKYP++++VA+LTGH+ RVL++AMSPDGE +V+ A DETLR W F+ + K
Sbjct: 405 NQLIIWKYPAMSRVAELTGHTARVLHMAMSPDGETVVSAAADETLRLWKCFTVDKEKK 578
Score = 61.6 bits (148), Expect(2) = 2e-50, Method: Compositional matrix adjust.
Identities = 31/59 (52%), Positives = 39/59 (66%), Gaps = 5/59 (8%)
Frame = +2
Query: 220 LQGHRQEVCGLKWSTDHQLLASGGNDNKLLVW-----NHSSLSPVQQYTEHLAAVKAIA 273
L GH QEVCGL+WS D + LASG NDN L VW +S P+ +++H AAVKA+A
Sbjct: 47 LSGHSQEVCGLRWSPDGKYLASGANDNLLCVWPAQVTGGNSTQPLHTFSQHQAAVKALA 223
Score = 47.0 bits (110), Expect(2) = 1e-06, Method: Compositional matrix adjust.
Identities = 26/79 (32%), Positives = 43/79 (54%), Gaps = 2/79 (2%)
Frame = +3
Query: 224 RQEVCGLKWSTDHQLLAS--GGNDNKLLVWNHSSLSPVQQYTEHLAAVKAIAWSPHQHGL 281
+ +VC L WS +H+ L S G N+L++W + ++S V + T H A V +A SP +
Sbjct: 333 KSQVCALLWSKEHRELISSHGFAQNQLIIWKYPAMSRVAELTGHTARVLHMAMSPDGETV 512
Query: 282 LASGGGTADRCIRFWNTLT 300
+++ AD +R W T
Sbjct: 513 VSAA---ADETLRLWKCFT 560
Score = 23.1 bits (48), Expect(2) = 1e-06, Method: Compositional matrix adjust.
Identities = 17/59 (28%), Positives = 24/59 (40%), Gaps = 5/59 (8%)
Frame = +2
Query: 136 LSVEGDSVTSVGWSERGNLVAVGTHKGFVQIWDAA-----AGKKLSMLEGHTARVGALA 189
LS V + WS G +A G + + +W A + + L H A V ALA
Sbjct: 47 LSGHSQEVCGLRWSPDGKYLASGANDNLLCVWPAQVTGGNSTQPLHTFSQHQAAVKALA 223
Score = 35.0 bits (79), Expect = 0.061, Method: Compositional matrix adjust.
Identities = 20/67 (29%), Positives = 34/67 (50%), Gaps = 13/67 (19%)
Frame = +2
Query: 346 QVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFW-------------NVFSKTRSTKE 392
V L+GHS V L SPDG+ + +GA D L W + FS+ ++ +
Sbjct: 35 HVGTLSGHSQEVCGLRWSPDGKYLASGANDNLLCVWPAQVTGGNSTQPLHTFSQHQAAVK 214
Query: 393 SVSVLNL 399
+++V++L
Sbjct: 215 ALAVVSL 235
>34005
Length = 456
Score = 124 bits (312), Expect(2) = 1e-31, Method: Compositional matrix adjust.
Identities = 62/114 (54%), Positives = 76/114 (66%), Gaps = 3/114 (2%)
Frame = +1
Query: 225 QEVCGLKWSTDHQLLASGGNDNKLLVWNHS---SLSPVQQYTEHLAAVKAIAWSPHQHGL 281
QEVCGL WS D LASG NDN + +W+ + + P+ T H AAVKA+AW P Q +
Sbjct: 115 QEVCGLSWSPDATFLASGSNDNSVNIWDSTLGMDVPPLHTLTSHQAAVKAVAWCPWQTRM 294
Query: 282 LASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNLAWSKHANELVSTHGYSQNQ 335
LA+GGGT DR IRFWNT TG ++ +DT SQVC++ W K ELVS HGY NQ
Sbjct: 295 LATGGGTNDRHIRFWNTNTGACVKAVDTQSQVCSVLWCKEHRELVSGHGYVMNQ 456
Score = 30.0 bits (66), Expect(2) = 1e-31, Method: Compositional matrix adjust.
Identities = 13/25 (52%), Positives = 15/25 (60%)
Frame = +3
Query: 187 ALAWNAEQLSSGSRDRMILQRDIRT 211
LAWN+ LSSGSR I D+R
Sbjct: 3 CLAWNSHILSSGSRSGNIHHHDVRV 77
Score = 41.2 bits (95), Expect = 8e-04, Method: Compositional matrix adjust.
Identities = 34/118 (28%), Positives = 48/118 (40%), Gaps = 8/118 (6%)
Frame = +1
Query: 133 LCDLSVEGDSVTSVGWSERGNLVAVGTHKGFVQIWDAAAG---KKLSMLEGHTARVGALA 189
C L+ + V + WS +A G++ V IWD+ G L L H A V A+A
Sbjct: 97 FCPLTPQ--EVCGLSWSPDATFLASGSNDNSVNIWDSTLGMDVPPLHTLTSHQAAVKAVA 270
Query: 190 WNAEQ-----LSSGSRDRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQLLASG 242
W Q G+ DR I + T Q +VC + W +H+ L SG
Sbjct: 271 WCPWQTRMLATGGGTNDRHIRFWNTNTGACVKAVDTQ---SQVCSVLWCKEHRELVSG 435
Score = 34.7 bits (78), Expect = 0.070, Method: Compositional matrix adjust.
Identities = 27/83 (32%), Positives = 37/83 (44%), Gaps = 6/83 (7%)
Frame = +1
Query: 306 CIDTGSQVCNLAWSKHANELVSTHGYSQNQILVWKYP---SLTQVAKLTGHSYRVLYLAM 362
C T +VC L+WS A L S G + N + +W + + LT H V +A
Sbjct: 100 CPLTPQEVCGLSWSPDATFLAS--GSNDNSVNIWDSTLGMDVPPLHTLTSHQAAVKAVAW 273
Query: 363 SP-DGEAIVTGAG--DETLRFWN 382
P + TG G D +RFWN
Sbjct: 274 CPWQTRMLATGGGTNDRHIRFWN 342
>29912
Length = 510
Score = 132 bits (333), Expect = 2e-31, Method: Compositional matrix adjust.
Identities = 72/152 (47%), Positives = 93/152 (61%), Gaps = 5/152 (3%)
Frame = +3
Query: 141 DSVTSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNAEQLSSGSR 200
+ + +V W + GN +A+GT G VQ+WD KKL + GH ARVG+L+WN+ +SSGSR
Sbjct: 12 EYIGAVSWIKEGNYLALGTSTGEVQVWDVTQQKKLRTMAGHAARVGSLSWNSFIVSSGSR 191
Query: 201 DRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVW-----NHSS 255
I D+R L GH QEVCGL+WS D + LASG NDN L VW +S
Sbjct: 192 SGNIHHHDVRVAD-HHVGTLSGHSQEVCGLRWSPDGKYLASGANDNLLCVWPAQVTGGNS 368
Query: 256 LSPVQQYTEHLAAVKAIAWSPHQHGLLASGGG 287
P+ +++H AAVKA+AW P Q LASGGG
Sbjct: 369 TQPLHTFSQHQAAVKALAWCPWQPSXLASGGG 464
Score = 34.3 bits (77), Expect = 0.085, Method: Compositional matrix adjust.
Identities = 16/36 (44%), Positives = 20/36 (55%)
Frame = +3
Query: 346 QVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFW 381
V L+GHS V L SPDG+ + +GA D L W
Sbjct: 234 HVGTLSGHSQEVCGLRWSPDGKYLASGANDNLLCVW 341
Score = 29.6 bits (65), Expect = 2.3, Method: Compositional matrix adjust.
Identities = 24/78 (30%), Positives = 34/78 (43%), Gaps = 8/78 (10%)
Frame = +3
Query: 136 LSVEGDSVTSVGWSERGNLVAVGTHKGFVQIWDAA-----AGKKLSMLEGHTARVGALAW 190
LS V + WS G +A G + + +W A + + L H A V ALAW
Sbjct: 246 LSGHSQEVCGLRWSPDGKYLASGANDNLLCVWPAQVTGGNSTQPLHTFSQHQAAVKALAW 425
Query: 191 NAEQ---LSSGSRDRMIL 205
Q L+SG D +I+
Sbjct: 426 CPWQPSXLASGGGDVLIV 479
>00561
Length = 1003
Score = 57.4 bits (137), Expect(2) = 2e-11, Method: Compositional matrix adjust.
Identities = 54/203 (26%), Positives = 95/203 (46%), Gaps = 6/203 (2%)
Frame = -3
Query: 143 VTSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNAE--QLSSGSR 200
++ V S GN G+ +++WD AAGK EGHT V ++A++A+ Q+ SGSR
Sbjct: 857 ISDVVLSSDGNYALSGSWDQTLRLWDLAAGKTTRRFEGHTKDVLSVAFSADNRQIVSGSR 678
Query: 201 DRMILQRDIRTPPLQSERRLQ--GHRQEVCGLKWSTDHQ--LLASGGNDNKLLVWNHSSL 256
D+ I + + + +Q GH V +++S +H ++ S G D + VWN ++
Sbjct: 677 DKTIKLWNTLA---ECKFTIQEDGHTDWVSCVRFSPNHSNPIIVSCGWDRTVKVWNLANC 507
Query: 257 SPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNL 316
+ H + + SP G L + GG + + W+ G+ L ++ + L
Sbjct: 506 KLKNNHHGHNGYLNTVTVSP--DGSLCTSGGKDSKAL-LWDLNDGKNLYTLEHNDIINAL 336
Query: 317 AWSKHANELVSTHGYSQNQILVW 339
+S + L +G S I +W
Sbjct: 335 CFSPNRYWLCVAYGPS---IKIW 276
Score = 28.5 bits (62), Expect(2) = 2e-11, Method: Compositional matrix adjust.
Identities = 12/28 (42%), Positives = 16/28 (57%)
Frame = -2
Query: 356 RVLYLAMSPDGEAIVTGAGDETLRFWNV 383
+ L LA S DG+ + G D T+R W V
Sbjct: 201 QCLSLAWSTDGQTLFAGYSDNTIRVWQV 118
Score = 57.0 bits (136), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 46/200 (23%), Positives = 88/200 (44%), Gaps = 7/200 (3%)
Frame = -3
Query: 191 NAEQLSSGSRDRMI----LQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDN 246
+ + + S SRD+ + L RD T ++RL GH + + S+D SG D
Sbjct: 977 DPDTIISASRDKTLIVWKLTRDEDTNYGYPQKRLYGHSHFISDVVLSSDGNYALSGSWDQ 798
Query: 247 KLLVWNHSSLSPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQC 306
L +W+ ++ +++ H V ++A+S +++ G+ D+ I+ WNTL
Sbjct: 797 TLRLWDLAAGKTTRRFEGHTKDVLSVAFSADNRQIVS---GSRDKTIKLWNTLAECKFTI 627
Query: 307 IDTGSQ---VCNLAWSKHANELVSTHGYSQNQILVWKYPSLTQVAKLTGHSYRVLYLAMS 363
+ G C H+N ++ + G+ + + VW + GH+ + + +S
Sbjct: 626 QEDGHTDWVSCVRFSPNHSNPIIVSCGWDRT-VKVWNLANCKLKNNHHGHNGYLNTVTVS 450
Query: 364 PDGEAIVTGAGDETLRFWNV 383
PDG +G D W++
Sbjct: 449 PDGSLCTSGGKDSKALLWDL 390
Score = 37.7 bits (86), Expect = 0.007, Method: Compositional matrix adjust.
Identities = 19/60 (31%), Positives = 33/60 (55%), Gaps = 1/60 (1%)
Frame = -3
Query: 332 SQNQIL-VWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKTRST 390
S +Q L +W + + GH+ VL +A S D IV+G+ D+T++ WN ++ + T
Sbjct: 809 SWDQTLRLWDLAAGKTTRRFEGHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTLAECKFT 630
Score = 29.6 bits (65), Expect = 2.5, Method: Compositional matrix adjust.
Identities = 13/34 (38%), Positives = 19/34 (55%)
Frame = -2
Query: 221 QGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHS 254
+ + + L WSTD Q L +G +DN + VW S
Sbjct: 216 KAEQPQCLSLAWSTDGQTLFAGYSDNTIRVWQVS 115
>27760
Length = 525
Score = 64.7 bits (156), Expect = 7e-11, Method: Compositional matrix adjust.
Identities = 31/32 (96%), Positives = 31/32 (96%)
Frame = -2
Query: 373 AGDETLRFWNVFSKTRSTKESVSVLNLFTRIR 404
AGDETLRFWNVFSKTRSTKES SVLNLFTRIR
Sbjct: 524 AGDETLRFWNVFSKTRSTKESKSVLNLFTRIR 429
>02147
Length = 1547
Score = 60.1 bits (144), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 49/228 (21%), Positives = 98/228 (42%), Gaps = 1/228 (0%)
Frame = +2
Query: 155 VAVGTHKGFVQIWDAAAGKKLSML-EGHTARVGALAWNAEQLSSGSRDRMILQRDIRTPP 213
A G +IWDA G++L H + + + L +GS ++++ D+
Sbjct: 218 AATGAADFSAKIWDAEKGEELQTFSHKHIVKSVDFSHDGTALLTGSNEKLLKVFDLVNTD 397
Query: 214 LQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKAIA 273
+ + GH + G + +D + + S +D + +W+ + VQQ T ++
Sbjct: 398 AEP-KSFAGHTSNIKGALFLSDGKRIISASDDKTVRLWSLETCQEVQQLTFDTPPT-SLT 571
Query: 274 WSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNLAWSKHANELVSTHGYSQ 333
SP ++ ++ T + I F+ T + ++ + + + + S H +E G
Sbjct: 572 LSPDKNTIIV----THSQNIAFYQADTLREMKKFEAEAPISSA--SLHQSERFFVAGGED 733
Query: 334 NQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFW 381
++ + Y + ++ GH V + SPDGE +G+ D TLR W
Sbjct: 734 FKMYKFDYETGKEIESFKGHFGPVHCVRFSPDGELYASGSEDGTLRLW 877
Score = 33.1 bits (74), Expect = 0.19, Method: Compositional matrix adjust.
Identities = 22/98 (22%), Positives = 45/98 (45%), Gaps = 1/98 (1%)
Frame = +2
Query: 287 GTADRCIRFWNTLTGQPLQCIDTGSQVCNLAWSKHANELVSTHGYSQNQILVWKYPSLTQ 346
G AD + W+ G+ LQ V ++ +S L++ G ++ + V+ +
Sbjct: 227 GAADFSAKIWDAEKGEELQTFSHKHIVKSVDFSHDGTALLT--GSNEKLLKVFDLVNTDA 400
Query: 347 VAK-LTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNV 383
K GH+ + DG+ I++ + D+T+R W++
Sbjct: 401 EPKSFAGHTSNIKGALFLSDGKRIISASDDKTVRLWSL 514
>13335
Length = 863
Score = 57.4 bits (137), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 52/203 (25%), Positives = 90/203 (44%), Gaps = 24/203 (11%)
Frame = +1
Query: 204 ILQRDIRTPPLQSERRLQGHRQ-EVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQY 262
++ D++T ++ E + VC S+ H L SG +D+ + +W ++ V+ Y
Sbjct: 4 VIVWDVKTGSIKGEYQHASKSSIRVCKFSPSSSH--LVSGSDDDTICMWEVATQKLVRSY 177
Query: 263 TEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQP------LQCIDTGSQVCNL 316
H +V A+A+SP+ H L SG D + W+ G + D G C
Sbjct: 178 VGHEDSVMALAYSPNGH-YLVSGSPNGD--LYVWDASFGHCRHLTLRVDAHDLGVTCCEF 348
Query: 317 A---------WSKHANELVSTHGYSQNQILVWKY------PSLTQVAK--LTGHSYRVLY 359
+ S N L++T G N I +W + P +T + L+GHS V+
Sbjct: 349 SPTFGTACAENSSTCNLLLATGG-KDNLIKLWTFSAQVGSPEVTLQCRDILSGHSDLVMA 525
Query: 360 LAMSPDGEAIVTGAGDETLRFWN 382
A SP + +G+ D+++R W+
Sbjct: 526 CAFSPSSALLASGSFDKSVRLWD 594
Score = 45.1 bits (105), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 61/220 (27%), Positives = 89/220 (40%), Gaps = 25/220 (11%)
Frame = +1
Query: 158 GTHKGFVQIWDAAAGKKLSMLEGHTARVGALAW--NAEQLSSGSRDRMILQRDIRTPPLQ 215
G+ + +W+ A K + GH V ALA+ N L SGS + + D +
Sbjct: 115 GSDDDTICMWEVATQKLVRSYVGHEDSVMALAYSPNGHYLVSGSPNGDLYVWDASFGHCR 294
Query: 216 S-ERRLQGHRQEV------------CGLKWSTDHQLLASGGNDNKLLVWNHS-------- 254
R+ H V C ST + LLA+GG DN + +W S
Sbjct: 295 HLTLRVDAHDLGVTCCEFSPTFGTACAENSSTCNLLLATGGKDNLIKLWTFSAQVGSPEV 474
Query: 255 SLSPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQ-- 312
+L + H V A A+SP LLAS G+ D+ +R W+++ G L I+
Sbjct: 475 TLQCRDILSGHSDLVMACAFSP-SSALLAS--GSFDKSVRLWDSVKGVALFSIEACHSRF 645
Query: 313 VCNLAWSKHANELVSTHGYSQNQILVWKYPSLTQVAKLTG 352
V A+S L S G I +WK LT + + G
Sbjct: 646 VTCCAFSIDGTLLAS--GSMDRIIKIWK---LTDTSSIMG 750
Score = 44.7 bits (104), Expect = 7e-05, Method: Compositional matrix adjust.
Identities = 50/182 (27%), Positives = 82/182 (45%), Gaps = 26/182 (14%)
Frame = +1
Query: 141 DSVTSVGWSERGNLVAVGTHKGFVQIWDAAAG--KKLSM-LEGHTARVGALAWN------ 191
DSV ++ +S G+ + G+ G + +WDA+ G + L++ ++ H V ++
Sbjct: 190 DSVMALAYSPNGHYLVSGSPNGDLYVWDASFGHCRHLTLRVDAHDLGVTCCEFSPTFGTA 369
Query: 192 -AEQ-------LSSGSRDRMI----LQRDIRTP--PLQSERRLQGHRQEVCGLKWSTDHQ 237
AE L++G +D +I + +P LQ L GH V +S
Sbjct: 370 CAENSSTCNLLLATGGKDNLIKLWTFSAQVGSPEVTLQCRDILSGHSDLVMACAFSPSSA 549
Query: 238 LLASGGNDNKLLVWNHSSLSPVQQYT---EHLAAVKAIAWSPHQHGLLASGGGTADRCIR 294
LLASG D + +W+ S+ V ++ H V A+S LLAS G+ DR I+
Sbjct: 550 LLASGSFDKSVRLWD--SVKGVALFSIEACHSRFVTCCAFSI-DGTLLAS--GSMDRIIK 714
Query: 295 FW 296
W
Sbjct: 715 IW 720
Score = 32.3 bits (72), Expect = 0.31, Method: Compositional matrix adjust.
Identities = 31/118 (26%), Positives = 53/118 (44%), Gaps = 11/118 (9%)
Frame = +1
Query: 154 LVAVGTHKGFVQIWDAAAG--------KKLSMLEGHTARVGALAWN--AEQLSSGSRDRM 203
L+A G +++W +A + +L GH+ V A A++ + L+SGS D+
Sbjct: 400 LLATGGKDNLIKLWTFSAQVGSPEVTLQCRDILSGHSDLVMACAFSPSSALLASGSFDKS 579
Query: 204 I-LQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQ 260
+ L ++ L S H + V +S D LLASG D + +W + S +
Sbjct: 580 VRLWDSVKGVALFSIEAC--HSRFVTCCAFSIDGTLLASGSMDRIIKIWKLTDTSSIM 747
>01327
Length = 2215
Score = 57.4 bits (137), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 56/243 (23%), Positives = 107/243 (44%), Gaps = 10/243 (4%)
Frame = +3
Query: 154 LVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNA--EQLSSGSRDRMILQRDIRT 211
L G+ V ++D G+ GH + + + A + S SRD+ I + +
Sbjct: 81 LCLSGSKDKSVVLYDYQNGRLEDRWTGHDREITKVCYGASCNGMFSASRDKTI--KMWQR 254
Query: 212 PPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKA 271
S R GH V + +TD+ LL SG DN + +W+ + + ++Q V
Sbjct: 255 GNSHSIRDFIGHDMVVTAIHLNTDNTLLCSGSRDNTVRIWDVETGACLRQNNIPQNLVTD 434
Query: 272 IAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNLAWSKHANE---LVST 328
+ W P H ++ +G D+ +R +++ T ++ T Q ++ A+ L +
Sbjct: 435 VKWLPGSHLIIQAG---EDKEVRIYDSRTLGIVRSF-TKKQYIQMSCDVTADGQFCLTCS 602
Query: 329 HGYSQN--QILVWKYPSLTQVAKLTGHSYRV---LYLAMSPDGEAIVTGAGDETLRFWNV 383
+G+ N + +W+ + + GH + L+L + D I T + D ++R WN+
Sbjct: 603 NGFGGNGCEATLWQLSDGSIQNEFKGHREAIEACLFLPSNQDMTLIATASRDCSVRVWNM 782
Query: 384 FSK 386
F+K
Sbjct: 783 FTK 791
>30256
Length = 961
Score = 56.2 bits (134), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 48/175 (27%), Positives = 78/175 (44%)
Frame = +3
Query: 131 TRLCDLSVEGDSVTSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAW 190
T +C ++ G S T S G V G+ +++WD +G L++L GH A V + +
Sbjct: 129 TGVCTHTLYGHSSTVRCLSLSGKKVVSGSRDATLRVWDIESGHCLNVLLGHMAAVRCVQY 308
Query: 191 NAEQLSSGSRDRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLV 250
+ +++ SG+ D + D T LQGH V L++ D + SG D + V
Sbjct: 309 DGKRVVSGAXDYTVRVWDPDTASCL--HTLQGHTNRVYSLQF--DGVYVVSGSLDTSIRV 476
Query: 251 WNHSSLSPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQ 305
W+ V H + + + LL S G AD ++ W+ TG+ LQ
Sbjct: 477 WDVRCGKLVHTLMGHQSLTSGLELKDN---LLVS--GNADSTVKVWDVHTGKCLQ 626
Score = 54.7 bits (130), Expect = 7e-08, Method: Compositional matrix adjust.
Identities = 58/239 (24%), Positives = 106/239 (44%), Gaps = 3/239 (1%)
Frame = +3
Query: 148 WSER--GNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNAEQLSSGSRDRMIL 205
WS + GN V G+ +++W+A G L GH++ V L+ + +++ SGSRD +
Sbjct: 54 WSSQMTGNTVISGSTDRSLKVWNADTGVCTHTLYGHSSTVRCLSLSGKKVVSGSRDATLR 233
Query: 206 QRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYTEH 265
DI + L GH V +++ D + + SG D + VW+ + S + H
Sbjct: 234 VWDIESG--HCLNVLLGHMAAVRCVQY--DGKRVVSGAXDYTVRVWDPDTASCLHTLQGH 401
Query: 266 LAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNLAWSKHANEL 325
V ++ Q + G+ D IR W+ G+ + + G Q N L
Sbjct: 402 TNRVYSL-----QFDGVYVVSGSLDTSIRVWDVRCGKLVHTL-MGHQSLTSGLELKDNLL 563
Query: 326 VSTHGYSQNQILVWKYPSLTQVAKLTG-HSYRVLYLAMSPDGEAIVTGAGDETLRFWNV 383
VS G + + + VW + + L G + +R + + + +VT + D T++ W++
Sbjct: 564 VS--GNADSTVKVWDVHTGKCLQTLLGPNKHRSAVTCLQFNKKFVVTCSDDGTVKLWDL 734
Score = 46.2 bits (108), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 55/215 (25%), Positives = 84/215 (39%)
Frame = +3
Query: 169 AAAGKKLSMLEGHTARVGALAWNAEQLSSGSRDRMILQRDIRTPPLQSERRLQGHRQEVC 228
A G+ + L GHT V + + SGS DR + + T L GH V
Sbjct: 3 AVTGRCIKNLIGHTGGVWSSQMTGNTVISGSTDRSLKVWNADTGV--CTHTLYGHSSTVR 176
Query: 229 GLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKAIAWSPHQHGLLASGGGT 288
L S + + SG D L VW+ S + H+AAV+ + + + + SG
Sbjct: 177 CL--SLSGKKVVSGSRDATLRVWDIESGHCLNVLLGHMAAVRCVQYDGKR---VVSGA-- 335
Query: 289 ADRCIRFWNTLTGQPLQCIDTGSQVCNLAWSKHANELVSTHGYSQNQILVWKYPSLTQVA 348
D +R W+ T C+ T N +S + + G I VW V
Sbjct: 336 XDYTVRVWDPDTA---SCLHTLQGHTNRVYSLQFDGVYVVSGSLDTSIRVWDVRCGKLVH 506
Query: 349 KLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNV 383
L GH + L + +V+G D T++ W+V
Sbjct: 507 TLMGH--QSLTSGLELKDNLLVSGNADSTVKVWDV 605
Score = 33.9 bits (76), Expect = 0.11, Method: Compositional matrix adjust.
Identities = 21/69 (30%), Positives = 32/69 (46%)
Frame = +3
Query: 317 AWSKHANELVSTHGYSQNQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDE 376
WS G + + VW + L GHS V L++S G+ +V+G+ D
Sbjct: 51 VWSSQMTGNTVISGSTDRSLKVWNADTGVCTHTLYGHSSTVRCLSLS--GKKVVSGSRDA 224
Query: 377 TLRFWNVFS 385
TLR W++ S
Sbjct: 225 TLRVWDIES 251
>19498
Length = 903
Score = 55.5 bits (132), Expect = 4e-08, Method: Compositional matrix adjust.
Identities = 54/208 (25%), Positives = 77/208 (37%), Gaps = 8/208 (3%)
Frame = -1
Query: 133 LCDLSVEGDSVTSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNA 192
LC + V V WSE G +A G + IW + G G G+
Sbjct: 807 LCQMDSHLGCVNCVRWSENGKFLASGGDDKLIMIWQISRG------FGSGKSFGS----- 661
Query: 193 EQLSSGSRDRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWN 252
+ IL+ +S L+GH +V L WS LAS DN ++VWN
Sbjct: 660 --------NVTILEH------WRSVATLRGHAGDVLDLAWSPQDLWLASCSVDNTIVVWN 523
Query: 253 HSSLSP-VQQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGS 311
S V H VK + W P L + + D+ +R W T + C+ +
Sbjct: 522 ALKFSEQVAVIRGHAGMVKGVTWDPVGRYLASQ---SDDKTLRVWRTSDWKEETCVKSCF 352
Query: 312 QVCN-------LAWSKHANELVSTHGYS 332
+ C L WS N +VS H +
Sbjct: 351 KECGGTTHVLRLNWSPDGNHVVSAHAMN 268
Score = 45.1 bits (105), Expect = 5e-05, Method: Compositional matrix adjust.
Identities = 50/192 (26%), Positives = 76/192 (39%), Gaps = 34/192 (17%)
Frame = -1
Query: 243 GNDNKLLVWNHSSLSPVQ---------------QYTEHLAAVKAIAWSPHQHGLLASGGG 287
G+ K+++WN ++P++ Q HL V + WS + LASGG
Sbjct: 891 GDSGKVVIWN---MAPIRDEKEEADDDVPRVLCQMDSHLGCVNCVRWSENGK-FLASGGD 724
Query: 288 TADRCIRFW--------------NTLTGQPLQCIDT----GSQVCNLAWSKHANELVSTH 329
D+ I W N + + + T V +LAWS L S
Sbjct: 723 --DKLIMIWQISRGFGSGKSFGSNVTILEHWRSVATLRGHAGDVLDLAWSPQDLWLASCS 550
Query: 330 GYSQNQILVWKYPSLT-QVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKTR 388
N I+VW + QVA + GH+ V + P G + + + D+TLR W +T
Sbjct: 549 --VDNTIVVWNALKFSEQVAVIRGHAGMVKGVTWDPVGRYLASQSDDKTLRVW----RTS 388
Query: 389 STKESVSVLNLF 400
KE V + F
Sbjct: 387 DWKEETCVKSCF 352
>17598
Length = 875
Score = 54.7 bits (130), Expect = 6e-08, Method: Compositional matrix adjust.
Identities = 48/202 (23%), Positives = 88/202 (43%), Gaps = 11/202 (5%)
Frame = +1
Query: 193 EQLSSGSRDRMILQRDI--RTPPLQSE------RRLQGHRQEVCGLKWSTDHQLLASGGN 244
E L G RD++++ D+ R + E R LQGH V + S D + + S
Sbjct: 4 EFLIXGGRDKLLIVWDLVPRKDGDEDETWGGPRRTLQGHSHFVSDVSLSADSRYVLSSSW 183
Query: 245 DNKLLVWNHSSLSPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPL 304
D L +W+ + +++ H A+A+SP +ASGG D+ ++ WNT+ G+
Sbjct: 184 DATLRLWDIKKGNTTRRFISHTRDALAVAFSPDNRQ-IASGG--RDKALKIWNTV-GECK 351
Query: 305 QCIDTGSQ---VCNLAWSKHANELVSTHGYSQNQILVWKYPSLTQVAKLTGHSYRVLYLA 361
+D S V + + + A + I VW ++T GH ++ +
Sbjct: 352 FTVDANSHQDWVTCVKFHQDAKSPLVVSASMDKTIKVWDNQTMTLKHTFVGHKTQINAID 531
Query: 362 MSPDGEAIVTGAGDETLRFWNV 383
++ + +G+ D + WN+
Sbjct: 532 LALKTYYLASGSKDGIVMTWNI 597
Score = 40.4 bits (93), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 45/212 (21%), Positives = 87/212 (41%), Gaps = 4/212 (1%)
Frame = +1
Query: 143 VTSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNAE--QLSSGSR 200
V+ V S V + +++WD G HT A+A++ + Q++SG R
Sbjct: 130 VSDVSLSADSRYVLSSSWDATLRLWDIKKGNTTRRFISHTRDALAVAFSPDNRQIASGGR 309
Query: 201 DRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQ--LLASGGNDNKLLVWNHSSLSP 258
D+ + + + H+ V +K+ D + L+ S D + VW++ +++
Sbjct: 310 DKALKIWNT-VGECKFTVDANSHQDWVTCVKFHQDAKSPLVVSASMDKTIKVWDNQTMTL 486
Query: 259 VQQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNLAW 318
+ H + AI + + L G+ D + WN G L ID +V + +
Sbjct: 487 KHTFVGHKTQINAIDLALKTYYL---ASGSKDGIVMTWNIQNGTFLGKIDCDCEVNAVKF 657
Query: 319 SKHANELVSTHGYSQNQILVWKYPSLTQVAKL 350
S + L G S+ I +W P+ ++ +
Sbjct: 658 SPNKYWLFV--GTSEG-IQIWDLPNQKKIKDI 744
Score = 33.9 bits (76), Expect = 0.11, Method: Compositional matrix adjust.
Identities = 16/67 (23%), Positives = 30/67 (44%)
Frame = +1
Query: 338 VWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKTRSTKESVSVL 397
+W + H+ L +A SPD I +G D+ L+ WN + + T ++ S
Sbjct: 199 LWDIKKGNTTRRFISHTRDALAVAFSPDNRQIASGGRDKALKIWNTVGECKFTVDANSHQ 378
Query: 398 NLFTRIR 404
+ T ++
Sbjct: 379 DWVTCVK 399
>03156
Length = 1014
Score = 54.3 bits (129), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 51/217 (23%), Positives = 98/217 (45%), Gaps = 10/217 (4%)
Frame = +1
Query: 180 GHTARVGALAWNA--EQLSSGSRDRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQ 237
GH + + + A + S SRD+ I + + S R GH V + +TD+
Sbjct: 49 GHDREITKVCYGASCNGMFSASRDKTI--KMWQRGNSHSIRDFIGHDMVVTAIHLNTDNT 222
Query: 238 LLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWN 297
LL SG DN + +W+ + + ++Q V + W P H ++ +G D+ +R ++
Sbjct: 223 LLCSGSRDNTVRIWDVETGACLRQNNIPQNLVTDVKWLPGSHLIIQAG---EDKEVRIYD 393
Query: 298 TLTGQPLQCIDTGSQVCNLAWSKHANE---LVSTHGYSQN--QILVWKYPSLTQVAKLTG 352
+ T ++ T Q ++ A+ L ++G+ N + +W+ + + G
Sbjct: 394 SRTLGIVRSF-TKKQYIQMSCDVTADGQFCLTCSNGFGGNGCEATLWQLSDGSIQNEFKG 570
Query: 353 HSYRV---LYLAMSPDGEAIVTGAGDETLRFWNVFSK 386
H + L+L + D I T + D ++R WN+F+K
Sbjct: 571 HREAIEACLFLPSNQDMTLIATASRDCSVRVWNMFTK 681
>27465
Length = 658
Score = 52.8 bits (125), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 37/141 (26%), Positives = 69/141 (48%), Gaps = 3/141 (2%)
Frame = -1
Query: 115 RRLQPSTPEKKGLFTVTRLCDLSVEGDSVTSVGWSERGNLVAVGTHKGFVQIWDAAAGKK 174
R+ +P LF V R L + T+V +++ G+ G++ +IWD A+ ++
Sbjct: 421 RKTRPKDDHHFYLFKVLRAHILPL-----TNVAFNKSGSSFITGSYDRTCKIWDTASAEE 257
Query: 175 LSMLEGHTARVGALAWN---AEQLSSGSRDRMILQRDIRTPPLQSERRLQGHRQEVCGLK 231
L LEGH V A+A+N +++ +GS D+ + T + L+GH E+ +
Sbjct: 256 LHTLEGHRNVVYAIAFNNPFGDKVITGSFDKTC--KLWSTADGKCYHTLRGHTAEIVCVS 83
Query: 232 WSTDHQLLASGGNDNKLLVWN 252
++ L+A+G D +W+
Sbjct: 82 FNPSSTLIATGSMDTTCRLWD 20
Score = 38.5 bits (88), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 24/98 (24%), Positives = 45/98 (45%), Gaps = 1/98 (1%)
Frame = -1
Query: 287 GTADRCIRFWNTLTGQPLQCIDTGSQVCN-LAWSKHANELVSTHGYSQNQILVWKYPSLT 345
G+ DR + W+T + + L ++ V +A++ + V T + + L W
Sbjct: 307 GSYDRTCKIWDTASAEELHTLEGHRNVVYAIAFNNPFGDKVITGSFDKTCKL-WSTADGK 131
Query: 346 QVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNV 383
L GH+ ++ ++ +P I TG+ D T R W+V
Sbjct: 130 CYHTLRGHTAEIVCVSFNPSSTLIATGSMDTTCRLWDV 17
>12806
Length = 961
Score = 50.8 bits (120), Expect = 9e-07, Method: Compositional matrix adjust.
Identities = 49/200 (24%), Positives = 81/200 (40%), Gaps = 11/200 (5%)
Frame = +3
Query: 195 LSSGSRDRMILQRDIRTPPLQSE--------RRLQGHRQEVCGLKWSTDHQLLASGGNDN 246
L SG RD I+ D+ E + L GH + L S D + S D
Sbjct: 54 LISGGRDNNIIVWDL*PKKDGDEDQTWGVPRKTLTGHSHFISDLALSADSRFALSSSWDA 233
Query: 247 KLLVWNHSSLSPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQC 306
L +W+ S ++ H V +A+SP +ASGG D+ ++ WN + G+
Sbjct: 234 TLRLWDIKKGSTTSRFINHTRDVLTVAFSPDNRQ-IASGG--RDKNLKIWNIM-GECKYT 401
Query: 307 IDTGSQ---VCNLAWSKHANELVSTHGYSQNQILVWKYPSLTQVAKLTGHSYRVLYLAMS 363
+D + V + + + + + I VW ++T GH ++ L MS
Sbjct: 402 VDANAHTDWVTCVRFHQDTKNPIVVSASNDKTIKVWDNHTMTLKNTFVGHKAQITALDMS 581
Query: 364 PDGEAIVTGAGDETLRFWNV 383
+ +V+G+ D WNV
Sbjct: 582 TN--YLVSGSKDGIAMTWNV 635
Score = 44.3 bits (103), Expect = 8e-05, Method: Compositional matrix adjust.
Identities = 44/192 (22%), Positives = 85/192 (44%), Gaps = 5/192 (2%)
Frame = +3
Query: 164 VQIWDAAAGKKLSMLEGHTARVGALAWNAE--QLSSGSRDRMILQRDIRTPPLQSERRLQ 221
+++WD G S HT V +A++ + Q++SG RD+ + +I +
Sbjct: 237 LRLWDIKKGSTTSRFINHTRDVLTVAFSPDNRQIASGGRDKNLKIWNI-MGECKYTVDAN 413
Query: 222 GHRQEVCGLKWSTDHQ--LLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKAIAWSPHQH 279
H V +++ D + ++ S ND + VW++ +++ + H A + A+ S +
Sbjct: 414 AHTDWVTCVRFHQDTKNPIVVSASNDKTIKVWDNHTMTLKNTFVGHKAQITALDMSTN-- 587
Query: 280 GLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNLAWSKHAN-ELVSTHGYSQNQILV 338
L S G+ D WN G + ID Q+ + ++ N + V +QN I +
Sbjct: 588 -YLVS--GSKDGIAMTWNVAEGSFVGKIDCDDQINAIKFNIENNKKKVWLFIGTQNGIQI 758
Query: 339 WKYPSLTQVAKL 350
W Y ++ +L
Sbjct: 759 WDYSGEKKIKEL 794
Score = 39.7 bits (91), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 17/67 (25%), Positives = 34/67 (50%)
Frame = +3
Query: 338 VWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKTRSTKESVSVL 397
+W + ++ H+ VL +A SPD I +G D+ L+ WN+ + + T ++ +
Sbjct: 243 LWDIKKGSTTSRFINHTRDVLTVAFSPDNRQIASGGRDKNLKIWNIMGECKYTVDANAHT 422
Query: 398 NLFTRIR 404
+ T +R
Sbjct: 423 DWVTCVR 443
Score = 35.4 bits (80), Expect = 0.044, Method: Compositional matrix adjust.
Identities = 25/77 (32%), Positives = 39/77 (50%), Gaps = 2/77 (2%)
Frame = +3
Query: 178 LEGHTARVGALAWNAEQ--LSSGSRDRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTD 235
L GH+ + LA +A+ S S D + DI+ S R H ++V + +S D
Sbjct: 153 LTGHSHFISDLALSADSRFALSSSWDATLRLWDIKKGSTTS--RFINHTRDVLTVAFSPD 326
Query: 236 HQLLASGGNDNKLLVWN 252
++ +ASGG D L +WN
Sbjct: 327 NRQIASGGRDKNLKIWN 377
Score = 28.9 bits (63), Expect = 3.6, Method: Compositional matrix adjust.
Identities = 18/73 (24%), Positives = 35/73 (47%), Gaps = 2/73 (2%)
Frame = +3
Query: 135 DLSVEGDSVTSVGWSE--RGNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNA 192
D + D VT V + + + +V ++ +++WD + GH A++ AL +
Sbjct: 405 DANAHTDWVTCVRFHQDTKNPIVVSASNDKTIKVWDNHTMTLKNTFVGHKAQITALDMST 584
Query: 193 EQLSSGSRDRMIL 205
L SGS+D + +
Sbjct: 585 NYLVSGSKDGIAM 623
>16389
Length = 558
Score = 50.4 bits (119), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 24/27 (88%), Positives = 25/27 (92%)
Frame = -3
Query: 378 LRFWNVFSKTRSTKESVSVLNLFTRIR 404
LRFWNVF +TRSTKES SVLNLFTRIR
Sbjct: 544 LRFWNVFRQTRSTKESKSVLNLFTRIR 464
>17266
Length = 480
Score = 50.1 bits (118), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 37/152 (24%), Positives = 62/152 (40%), Gaps = 3/152 (1%)
Frame = -1
Query: 230 LKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTA 289
L + D + SG D +W+ Q ++ H + + AI + P+ H G+
Sbjct: 441 LSLAPDMRTFVSGACDASAKLWDVRDGMCKQTFSGHESDINAITYFPNGHAFAT---GSD 271
Query: 290 DRCIRFWNTLTGQPLQCIDTGSQVCNL---AWSKHANELVSTHGYSQNQILVWKYPSLTQ 346
D R ++ Q + + +C + A+SK L+ GY +W +
Sbjct: 270 DATCRLFDIRADQEIGMYSHDNIICGITSVAFSKSGRLLLG--GYDDFNCNIWDVLKQER 97
Query: 347 VAKLTGHSYRVLYLAMSPDGEAIVTGAGDETL 378
L GH RV L ++ DG A+ TG+ D L
Sbjct: 96 TGVLAGHDNRVSCLGVTEDGSAVATGSWDSFL 1
Score = 31.6 bits (70), Expect = 0.60, Method: Compositional matrix adjust.
Identities = 19/64 (29%), Positives = 31/64 (48%), Gaps = 2/64 (3%)
Frame = -1
Query: 143 VTSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAW--NAEQLSSGSR 200
+TSV +S+ G L+ G IWD ++ +L GH RV L + +++GS
Sbjct: 192 ITSVAFSKSGRLLLGGYDDFNCNIWDVLKQERTGVLAGHDNRVSCLGVTEDGSAVATGSW 13
Query: 201 DRMI 204
D +
Sbjct: 12 DSFL 1
>03387
Length = 1891
Score = 50.1 bits (118), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 38/154 (24%), Positives = 72/154 (46%), Gaps = 21/154 (13%)
Frame = +1
Query: 164 VQIWDA---AAGKKLSMLEGHTARVGALAWNAEQ---LSSGSRDRMILQRDIRTPPLQSE 217
+ IWD K +++ HTA V L++N L++GS D+ + D+R L+
Sbjct: 586 LMIWDTRSNTTSKPSHVVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKL- 762
Query: 218 RRLQGHRQEVCGLKWSTDHQ-LLASGGNDNKLLVWNHSSLSPVQQYTE------------ 264
+ H+ E+ ++WS ++ +LAS G D +L VW+ S + Q +
Sbjct: 763 HSFESHKDEIFQVQWSPHNETILASSGTDRRLHVWDLSKIGEEQLPEDAEDGPPELLFIH 942
Query: 265 --HLAAVKAIAWSPHQHGLLASGGGTADRCIRFW 296
H A + +W+P++ ++ S + D ++ W
Sbjct: 943 GGHTAKISDFSWNPNEPWIVCS--VSEDNIMQVW 1038
Score = 43.5 bits (101), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 46/200 (23%), Positives = 85/200 (42%), Gaps = 16/200 (8%)
Frame = +1
Query: 114 DRRLQPSTPEKKGLFTVTRLCDLSVEGDSVTSVGWSERGNL---VAVGTHKGFVQIWDAA 170
D PS P+ G + +L ++G G S NL + + + +WD
Sbjct: 289 DYTKHPSKPDPSG----ECIPELRLKGHQKEGYGLSWNPNLNGHLLSASDDHTICLWDIN 456
Query: 171 AGKKLS-------MLEGHTARVGALAWN---AEQLSSGSRDRMILQRDIRTPPL-QSERR 219
+ ++ S + GHT+ V +AW+ S + D+ ++ D R+ +
Sbjct: 457 STQRESRVVDAHTIFTGHTSVVEDVAWHLLHESLFGSVADDQKLMIWDTRSNTTSKPSHV 636
Query: 220 LQGHRQEVCGLKWSTDHQ-LLASGGNDNKLLVWNHSSLS-PVQQYTEHLAAVKAIAWSPH 277
+ H EV L ++ + +LA+G D + +W+ +L + + H + + WSPH
Sbjct: 637 VDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPH 816
Query: 278 QHGLLASGGGTADRCIRFWN 297
+LAS G DR + W+
Sbjct: 817 NETILASSG--TDRRLHVWD 870
>19949
Length = 903
Score = 49.7 bits (117), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 46/198 (23%), Positives = 85/198 (42%), Gaps = 6/198 (3%)
Frame = +2
Query: 143 VTSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNAEQ--LSSGSR 200
V S+ + G A G+ V++WD + +GHT V L ++ + ++S S
Sbjct: 2 VKSLDFHPYGAYTASGSMDCNVKLWDIRRKGCIYTYKGHTGCVCCLRFSPDGRWIASASE 181
Query: 201 DRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQ 260
D ++ D+ L ++ +L HR V +++ LLASG D + W+ + +
Sbjct: 182 DGLVKLWDLTAGKLLTDLKL--HRDAVNTIEFHPHEFLLASGSADRTVKFWDLETFQLIS 355
Query: 261 QYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGS----QVCNL 316
++++I + H G+ G + W +PL+ DT S QVC++
Sbjct: 356 TTEPEANSIRSILF--HPDGVCLYSGSKDTLKVYHW-----EPLELYDTVSVPWGQVCDM 514
Query: 317 AWSKHANELVSTHGYSQN 334
+ S +L+ Y N
Sbjct: 515 SISN--TQLIGASFYKTN 562
>16105
Length = 960
Score = 48.1 bits (113), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 33/117 (28%), Positives = 53/117 (45%), Gaps = 8/117 (6%)
Frame = -2
Query: 220 LQGHRQEVCGLKWST-DHQLLASGGNDNKLLVWN--HSSL-----SPVQQYTEHLAAVKA 271
+ GH+ V ++W + ++AS +D + VW S L PV H
Sbjct: 587 VAGHKGAVLDIQWCPHNDNVIASASDDCTVKVWQIPDSGLVTNLTDPVVDLVGHQKRCCL 408
Query: 272 IAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNLAWSKHANELVST 328
I W P +L S G AD I FWN TG+P+ +D + ++++ + + LV T
Sbjct: 407 IVWHPSAQNVLVSAG--ADNKILFWNVGTGEPMLEVDVPDMIYCMSFNFNGSRLVCT 243
>02960
Length = 1577
Score = 46.2 bits (108), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 67/281 (23%), Positives = 117/281 (41%), Gaps = 40/281 (14%)
Frame = +2
Query: 158 GTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNAEQLSS-------GSRDR--MILQRD 208
G++ V++W + G+ + + GHT+ V +AW SS GS D+ ++ Q
Sbjct: 533 GSYDNTVRLW-STKGEAIMTIPGHTSPVKCVAWIKHDESSGVSTFVTGSHDQTALVWQWQ 709
Query: 209 IRTPPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHS-------------- 254
T + +GH V + S D Q + +G D L +W+
Sbjct: 710 RETNEVDCRLSCRGHAASVDCVAVSPDSQQMCTGSWDKMLKLWSTDCNVDGDQSEDTERP 889
Query: 255 ------------SLSPVQQYTEHLAAVKAIAW-SPHQHGLLASGGGTADRCIRFWNTLTG 301
+ PV + H AV A+ W PH+ ++ S + D +R W+ T
Sbjct: 890 SKKKKSAKSTTQTRVPVLTLSGHAEAVSAVRWLDPHR--VVTS---SWDHSLRLWDLHTA 1054
Query: 302 QPLQCIDTGSQVCNLAWSKHANELVSTHGYSQNQI-LVWKYPSLTQVAK--LTGHSYRVL 358
Q I V ++A+S ++ L++ G + + LV S + K T H+ V
Sbjct: 1055QQTSLIQGSKAVLDVAYSPLSHMLIT--GSADRHVRLVDPRCSEGETVKCAFTSHTGWVT 1228
Query: 359 YLAMSPDGEAI-VTGAGDETLRFWNVFSKTRSTKESVSVLN 398
+ SP E + ++G+ D L+ W+ TRS K ++ +N
Sbjct: 1229GVDWSPTREHLFLSGSYDNVLKLWD----TRSPKATLYDMN 1339
Score = 37.4 bits (85), Expect = 0.010, Method: Compositional matrix adjust.
Identities = 33/120 (27%), Positives = 58/120 (48%), Gaps = 6/120 (5%)
Frame = +2
Query: 142 SVTSVGWSERGNLVAVGTHKGFVQIWD--AAAGKKLSM-LEGHTARVGALAWNAEQ---L 195
+V V +S +++ G+ V++ D + G+ + HT V + W+ +
Sbjct: 1085 AVLDVAYSPLSHMLITGSADRHVRLVDPRCSEGETVKCAFTSHTGWVTGVDWSPTREHLF 1264
Query: 196 SSGSRDRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSS 255
SGS D ++ D R+P + + H + + WS +LL SGG DNKL V+++SS
Sbjct: 1265 LSGSYDNVLKLWDTRSPK-ATLYDMNWHEDRILAVDWSIP-ELLLSGGVDNKLHVFSYSS 1438
>12574
Length = 521
Score = 45.4 bits (106), Expect = 5e-05, Method: Compositional matrix adjust.
Identities = 31/110 (28%), Positives = 55/110 (50%), Gaps = 2/110 (1%)
Frame = +3
Query: 178 LEGHTARVGALAW--NAEQLSSGSRDRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTD 235
L GHT + A+ + N + L+S S D++I + + E+ + GH+ + + WS+D
Sbjct: 174 LAGHTKALSAVKFSPNGDWLASSSADKLI--KIWGAYDGKFEKTIAGHKLGLSDVAWSSD 347
Query: 236 HQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKAIAWSPHQHGLLASG 285
+LL S +D L +W S+ ++ H V ++P Q L+ SG
Sbjct: 348 SKLLCSASDDKTLKIWEFSTGKCMKTLKGHSNYVFCCNFNP-QSNLIVSG 494
Score = 38.5 bits (88), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 31/112 (27%), Positives = 56/112 (50%), Gaps = 3/112 (2%)
Frame = +3
Query: 265 HLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQV--CNLAWSKHA 322
H A+ A+ +SP+ L +S +AD+ I+ W G+ + I G ++ ++AWS +
Sbjct: 183 HTKALSAVKFSPNGDWLASS---SADKLIKIWGAYDGKFEKTI-AGHKLGLSDVAWSSDS 350
Query: 323 NELVSTHGYSQNQIL-VWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGA 373
L S S ++ L +W++ + + L GHS V +P IV+G+
Sbjct: 351 KLLCSA---SDDKTLKIWEFSTGKCMKTLKGHSNYVFCCNFNPQSNLIVSGS 497
Score = 37.4 bits (85), Expect = 0.010, Method: Compositional matrix adjust.
Identities = 25/103 (24%), Positives = 50/103 (48%), Gaps = 2/103 (1%)
Frame = +3
Query: 142 SVTSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNAEQ--LSSGS 199
++++V +S G+ +A + ++IW A GK + GH + +AW+++ L S S
Sbjct: 192 ALSAVKFSPNGDWLASSSADKLIKIWGAYDGKFEKTIAGHKLGLSDVAWSSDSKLLCSAS 371
Query: 200 RDRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQLLASG 242
D+ + + T + + L+GH V ++ L+ SG
Sbjct: 372 DDKTLKIWEFSTG--KCMKTLKGHSNYVFCCNFNPQSNLIVSG 494
Score = 28.9 bits (63), Expect = 3.7, Method: Compositional matrix adjust.
Identities = 10/43 (23%), Positives = 23/43 (53%)
Frame = +3
Query: 342 PSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVF 384
P+ T L GH+ + + SP+G+ + + + D+ ++ W +
Sbjct: 150 PTYTLKFTLAGHTKALSAVKFSPNGDWLASSSADKLIKIWGAY 278
>01598
Length = 1545
Score = 45.1 bits (105), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 43/185 (23%), Positives = 72/185 (38%), Gaps = 26/185 (14%)
Frame = +1
Query: 138 VEGDSVTSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWN------ 191
V+G T + WS N AVGT +G V + K ++ + + + W+
Sbjct: 967 VKGLKATELSWSPDQNAAAVGTDEGSVYVVTIQDLKIVAAIRTQQKLINCVRWHPRLTDQ 1146
Query: 192 -------AEQLSSGSRDRMILQRDIRTP------------PLQSERRLQGHRQEVCGLKW 232
L++ D++I D+ + L S R L GH Q V + W
Sbjct: 1147 SPAGSPCCHWLAAAGNDQVIHVVDLASVFAEREGDKETSLILTSLRELSGHSQRVTDMSW 1326
Query: 233 STDHQL-LASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTADR 291
S H L S G D + VW+ + + Q+ H+ + +S L+ +GG +D
Sbjct: 1327 SPHHDARLVSVGYDAEAFVWDVQKGTALAQFKGHMGRLLTCQFSGLDPDLVMTGG--SDA 1500
Query: 292 CIRFW 296
+ W
Sbjct: 1501 SVHVW 1515
>01805
Length = 2124
Score = 44.3 bits (103), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 57/261 (21%), Positives = 106/261 (40%), Gaps = 20/261 (7%)
Frame = -1
Query: 152 GNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNAEQLSSGSRDRMILQRDIRT 211
GN VA+G+ + ++IWD L ++E VG L+ GS+ + ++
Sbjct: 726 GNFVAIGSMEPVIEIWD------LDIMES----VGP------TLTLGSKPKKTKKK---- 607
Query: 212 PPLQSERRLQGHRQEVCGLKWSTD-HQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVK 270
++ + + GH Q V L W+ + +LAS D + +W+ S +T+H V+
Sbjct: 606 --MKQKESVTGHTQAVLDLSWNRNARHVLASASADTTVALWDLSEGKMAMNFTQHSREVQ 433
Query: 271 AIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNLAWS----------K 320
W P + L +G F NT+ + + C ++ C+ +W+
Sbjct: 432 CCNWHPQEEQTLLTGS--------FDNTV--KVVDC--RSAETCHKSWTVEGEVEKAVWN 289
Query: 321 HANELVSTHGYSQNQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAI-VTGAGDETLR 379
H N L + + + V + HS V + +S + +T + D+T++
Sbjct: 288 HHNPLQLLACTDKGMVYCFDIRHEKPVFSVGAHSSCVTGVCLSSQIPGLMITTSEDKTMK 109
Query: 380 FWN--------VFSKTRSTKE 392
W+ VFS+ KE
Sbjct: 108 VWDIQDDKPTHVFSRNLKMKE 46
>01249
Length = 1743
Score = 43.5 bits (101), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 36/115 (31%), Positives = 53/115 (46%), Gaps = 14/115 (12%)
Frame = -1
Query: 155 VAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNAEQ--LSSGSRDRMILQRDIRTP 212
VA + G ++WD +G L + T VG L + ++ L +G + IL +
Sbjct: 1161 VASSSSDGTCKLWDMLSGALLRTMVYETG-VGCLIMDKQEHFLLAGLDNGDILCSPLFGQ 985
Query: 213 PLQSE------------RRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSS 255
QSE R LQGH V L +S+D Q LASG + K+++WN S
Sbjct: 984 ISQSEVFVSKHTTKAGERVLQGHSDAVTCLAFSSDGQRLASGSQNGKVIIWNMES 820
Score = 34.3 bits (77), Expect = 0.097, Method: Compositional matrix adjust.
Identities = 28/110 (25%), Positives = 52/110 (47%), Gaps = 12/110 (10%)
Frame = -1
Query: 288 TADRCIRFWNTLTGQPLQCIDTGSQVCNLAWSKHANELVS--THG----------YSQNQ 335
++D + W+ L+G L+ + + V L K + L++ +G SQ++
Sbjct: 1149 SSDGTCKLWDMLSGALLRTMVYETGVGCLIMDKQEHFLLAGLDNGDILCSPLFGQISQSE 970
Query: 336 ILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFS 385
+ V K+ + L GHS V LA S DG+ + +G+ + + WN+ S
Sbjct: 969 VFVSKHTTKAGERVLQGHSDAVTCLAFSSDGQRLASGSQNGKVIIWNMES 820
>15780
Length = 735
Score = 41.6 bits (96), Expect = 6e-04, Method: Compositional matrix adjust.
Identities = 21/60 (35%), Positives = 34/60 (56%)
Frame = -1
Query: 324 ELVSTHGYSQNQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNV 383
+ +ST G + + ++VW S T VA LT H+ V L S DG + +G D ++R W++
Sbjct: 735 KYLSTAG-ADHTVIVWDIASGTAVAHLTAHTDTVYALCFSRDGTVLASGGMDNSIRLWDL 559
Score = 33.9 bits (76), Expect = 0.11, Method: Compositional matrix adjust.
Identities = 19/60 (31%), Positives = 30/60 (50%)
Frame = -1
Query: 193 EQLSSGSRDRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWN 252
+ LS+ D ++ DI + + L H V L +S D +LASGG DN + +W+
Sbjct: 735 KYLSTAGADHTVIVWDIASG--TAVAHLTAHTDTVYALCFSRDGTVLASGGMDNSIRLWD 562
Score = 29.6 bits (65), Expect = 2.5, Method: Compositional matrix adjust.
Identities = 16/43 (37%), Positives = 23/43 (53%), Gaps = 2/43 (4%)
Frame = -1
Query: 164 VQIWDAAAGKKLSMLEGHTARVGALAW--NAEQLSSGSRDRMI 204
V +WD A+G ++ L HT V AL + + L+SG D I
Sbjct: 702 VIVWDIASGTAVAHLTAHTDTVYALCFSRDGTVLASGGMDNSI 574
>31474
Length = 403
Score = 40.4 bits (93), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 30/118 (25%), Positives = 48/118 (40%), Gaps = 5/118 (4%)
Frame = -3
Query: 121 TPEKKGLFTVTRLCDLSVEGDSVTSVGWSERGNLVAVGTHKGFVQIWDAAAGK---KLSM 177
T K + T+ +C LS + V W+ G L+A ++IW K ++
Sbjct: 362 THAKMAMATLEEVCCLSAHDEHAWCVAWNPTGTLLASCGSDKIIKIWGKEGDNWVCKSTL 183
Query: 178 LEGHTARVGALAWN--AEQLSSGSRDRMILQRDIRTPPLQSERRLQGHRQEVCGLKWS 233
+ HT V +L W+ LSS S D + + L+GH EV + W+
Sbjct: 182 TDAHTRTVRSLGWSPCGNYLSSASFDATTAVWSRKGGEFECIATLEGHENEVKAVAWA 9
Score = 29.3 bits (64), Expect = 3.1, Method: Compositional matrix adjust.
Identities = 24/93 (25%), Positives = 42/93 (45%), Gaps = 3/93 (3%)
Frame = -3
Query: 220 LQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYT---EHLAAVKAIAWSP 276
L H + + W+ LLAS G+D + +W + V + T H V+++ WSP
Sbjct: 317 LSAHDEHAWCVAWNPTGTLLASCGSDKIIKIWGKEGDNWVCKSTLTDAHTRTVRSLGWSP 138
Query: 277 HQHGLLASGGGTADRCIRFWNTLTGQPLQCIDT 309
+ L ++ + D W+ G+ +CI T
Sbjct: 137 CGNYLSSA---SFDATTAVWSRKGGE-FECIAT 51
>30295
Length = 593
Score = 40.0 bits (92), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 21/73 (28%), Positives = 38/73 (52%)
Frame = +2
Query: 214 LQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKAIA 273
+++ R L+ H ++ + W+TD + L S D KL+VW+ + + V + V A
Sbjct: 215 MRTRRTLRXHLAKIYAMHWATDSRNLVSASQDGKLIVWDGYTTNKVHAIPLRSSWVMTCA 394
Query: 274 WSPHQHGLLASGG 286
++P G +A GG
Sbjct: 395 YAP-SGGYVACGG 430
>14555
Length = 627
Score = 39.3 bits (90), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 29/86 (33%), Positives = 39/86 (45%), Gaps = 10/86 (11%)
Frame = -3
Query: 328 THGYSQNQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFW------ 381
T+ Y+ N VW + L GH RV L +SPDG ++ TG+ D TLR W
Sbjct: 409 TNDYTVN---VWDALKGMRSTILYGHDNRVSCLRISPDGTSLCTGSWDYTLRIWA*ERER 239
Query: 382 ----NVFSKTRSTKESVSVLNLFTRI 403
N+ T T E L +FT +
Sbjct: 238 GHSSNIIRITL*TWEQCQ*LCVFTWV 161
Score = 28.9 bits (63), Expect = 4.0, Method: Compositional matrix adjust.
Identities = 16/48 (33%), Positives = 25/48 (52%), Gaps = 2/48 (4%)
Frame = -3
Query: 159 THKGFVQIWDAAAGKKLSMLEGHTARVGAL--AWNAEQLSSGSRDRMI 204
T+ V +WDA G + ++L GH RV L + + L +GS D +
Sbjct: 409 TNDYTVNVWDALKGMRSTILYGHDNRVSCLRISPDGTSLCTGSWDYTL 266
>10264
Length = 416
Score = 38.5 bits (88), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 25/84 (29%), Positives = 38/84 (45%), Gaps = 1/84 (1%)
Frame = -1
Query: 214 LQSERRLQGHRQEVCGLKWSTDHQL-LASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKAI 272
L S R L GH Q V + WS H L S G D + VW+ + + Q+ H+ +
Sbjct: 275 LTSLRELSGHSQRVTDMSWSPHHDARLVSVGYDAEAFVWDVQKGTALAQFKGHMGRLLTC 96
Query: 273 AWSPHQHGLLASGGGTADRCIRFW 296
+S L+ +GG +D + W
Sbjct: 95 QFSGLDPDLVMTGG--SDASVHVW 30
Score = 33.1 bits (74), Expect = 0.19, Method: Compositional matrix adjust.
Identities = 21/65 (32%), Positives = 33/65 (50%), Gaps = 2/65 (3%)
Frame = -1
Query: 123 EKKGLFTVTRLCDLSVEGDSVTSVGWSERGN--LVAVGTHKGFVQIWDAAAGKKLSMLEG 180
+K+ L +T L +LS VT + WS + LV+VG + +WD G L+ +G
Sbjct: 296 DKETLLILTSLRELSGHSQRVTDMSWSPHHDARLVSVG-YDAEAFVWDVQKGTALAQFKG 120
Query: 181 HTARV 185
H R+
Sbjct: 119 HMGRL 105
>01768
Length = 1424
Score = 37.7 bits (86), Expect = 0.008, Method: Compositional matrix adjust.
Identities = 57/233 (24%), Positives = 96/233 (41%), Gaps = 23/233 (9%)
Frame = +3
Query: 132 RLCDLSVEGDSVTSVGWSERGNLVAVGTHKGFVQIWDA-AAGKKLSM-------LEGHTA 183
R+ D++ D + + WS++G++ + DA AAGK S + HT
Sbjct: 534 RVTDIN---DKIYTGSWSDKGSVYVYDITXQTAIVDDAEAAGKYDSTQKSIVHTVTHHTT 704
Query: 184 RVGALAWNAEQ---LSSGSRDRMILQRDIRTPPLQSERR-LQGHRQEVCGLKWSTDH-QL 238
A+ W+ L +G I + +E+ H V ++WS + +
Sbjct: 705 EGFAIDWSPAAKGWLVTGDCTGAIYISQPSSSGWTTEKSSYAAHTDSVEDVQWSPNEGNV 884
Query: 239 LASGGNDNKLLVWN---HSSLSPVQQYTE-HLAAVKAIAWSPHQHGLLASGGGTADRCIR 294
AS D L +WN S + V E H + I W+P + LLASGG D I+
Sbjct: 885 FASCSVDRTLRIWNTQQKPSKANVLTVPEAHSRDINVINWNPIEKHLLASGGD--DGIIK 1058
Query: 295 FWN--TLTGQPLQC---IDTGSQ-VCNLAWSKHANELVSTHGYSQNQILVWKY 341
W+ +P+ SQ V +L W+ + +++ G +QI +W +
Sbjct: 1059IWDLRMFRNKPVSAQASFKLHSQPVTSLEWNPQDSSVLAASG-EDDQITIWDF 1214
>27475
Length = 369
Score = 37.4 bits (85), Expect = 0.010, Method: Compositional matrix adjust.
Identities = 26/78 (33%), Positives = 40/78 (51%), Gaps = 3/78 (3%)
Frame = +2
Query: 181 HTARVGALAWNAEQ---LSSGSRDRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQ 237
HT V + W+ + SGS D ++ D R+P + + H + + WS +
Sbjct: 65 HTGWVTGVDWSPTREHLFLSGSYDNVLKLWDTRSPK-ATLYDMNWHEDRILAVDWSIP-E 238
Query: 238 LLASGGNDNKLLVWNHSS 255
LL SGG DNKL V+++SS
Sbjct: 239 LLLSGGVDNKLHVFSYSS 292
Score = 27.7 bits (60), Expect = 8.7, Method: Compositional matrix adjust.
Identities = 12/37 (32%), Positives = 19/37 (51%)
Frame = +2
Query: 262 YTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNT 298
+T H V + WSP + L S G+ D ++ W+T
Sbjct: 56 FTSHTGWVTGVDWSPTREHLFLS--GSYDNVLKLWDT 160
>19863
Length = 502
Score = 36.6 bits (83), Expect = 0.018, Method: Compositional matrix adjust.
Identities = 25/72 (34%), Positives = 33/72 (45%)
Frame = +1
Query: 194 QLSSGSRDRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNH 253
QL SGS D I+ D+ + RLQGH V + +S D L S NDN + +WN
Sbjct: 13 QLVSGSSDMSIVVWDVENGV--QKLRLQGHAGWVNDVHFSQDQCWLLSCSNDNTVRIWNI 186
Query: 254 SSLSPVQQYTEH 265
+ EH
Sbjct: 187 EESDQIPIVMEH 222
Score = 33.5 bits (75), Expect = 0.16, Method: Compositional matrix adjust.
Identities = 20/60 (33%), Positives = 32/60 (53%)
Frame = +1
Query: 324 ELVSTHGYSQNQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNV 383
+LVS G S I+VW + Q +L GH+ V + S D +++ + D T+R WN+
Sbjct: 13 QLVS--GSSDMSIVVWDVENGVQKLRLQGHAGWVNDVHFSQDQCWLLSCSNDNTVRIWNI 186
>18981
Length = 407
Score = 36.2 bits (82), Expect = 0.025, Method: Compositional matrix adjust.
Identities = 34/121 (28%), Positives = 54/121 (44%), Gaps = 8/121 (6%)
Frame = -2
Query: 201 DRMIL----QRDIRTPPLQSE---RRLQGHRQEV-CGLKWSTDHQLLASGGNDNKLLVWN 252
D MI+ R +R L++ L+GH +V C + + + SG D L+VW
Sbjct: 388 DNMIISAATDRTLRVWCLKNTCLLHTLRGHNDDVECVCIYG---RRVVSGSWDKTLIVWE 218
Query: 253 HSSLSPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQ 312
+ PV Q H A+ A+ + + + G+AD +R W TGQ L + TG
Sbjct: 217 VDTGRPVHQLHGHTEAITAVQFDEGK-----AVSGSADGDVRTWALDTGQCLLTMTTGQD 53
Query: 313 V 313
+
Sbjct: 52 I 50
Score = 28.9 bits (63), Expect = 3.6, Method: Compositional matrix adjust.
Identities = 19/69 (27%), Positives = 33/69 (47%)
Frame = -2
Query: 152 GNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNAEQLSSGSRDRMILQRDIRT 211
G V G+ + +W+ G+ + L GHT + A+ ++ + SGS D D+RT
Sbjct: 268 GRRVVSGSWDKTLIVWEVDTGRPVHQLHGHTEAITAVQFDEGKAVSGSAD-----GDVRT 104
Query: 212 PPLQSERRL 220
L + + L
Sbjct: 103 WALDTGQCL 77
>13278
Length = 870
Score = 35.8 bits (81), Expect = 0.031, Method: Compositional matrix adjust.
Identities = 26/115 (22%), Positives = 49/115 (42%), Gaps = 9/115 (7%)
Frame = +1
Query: 220 LQGHRQEVCGLKWS---------TDHQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVK 270
LQ +E+ +KWS +LAS D+ + +W + T+H V
Sbjct: 37 LQLTTKEIYTIKWSPTGPGTSNPNTSLILASASFDSTVRLWEVERGLCLHTLTKHQEPVY 216
Query: 271 AIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNLAWSKHANEL 325
++A+SP L + G+ D+C+ WN TG + + + W+ +++
Sbjct: 217 SVAFSPDGKYLAS---GSFDKCVHIWNVQTGSLVHSYKGTGGIFEVCWNHRGDKV 372
Score = 33.5 bits (75), Expect = 0.15, Method: Compositional matrix adjust.
Identities = 14/34 (41%), Positives = 21/34 (61%)
Frame = +1
Query: 350 LTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNV 383
LT H V +A SPDG+ + +G+ D+ + WNV
Sbjct: 190 LTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNV 291
Score = 30.4 bits (67), Expect = 1.5, Method: Compositional matrix adjust.
Identities = 26/94 (27%), Positives = 41/94 (43%), Gaps = 9/94 (9%)
Frame = +1
Query: 220 LQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKAIAWSPH-- 277
L H++ V + +S D + LASG D + +WN + S V Y + + + W+
Sbjct: 190 LTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNVQTGSLVHSY-KGTGGIFEVCWNHRGD 366
Query: 278 QHGLLASGGGTA-------DRCIRFWNTLTGQPL 304
+ G AS G D+C W+ L PL
Sbjct: 367 KVGASASDGSVFVLDLRK*DKCSNSWHMLLLPPL 468
>02090
Length = 1841
Score = 35.8 bits (81), Expect = 0.032, Method: Compositional matrix adjust.
Identities = 18/52 (34%), Positives = 27/52 (51%)
Frame = -3
Query: 332 SQNQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNV 383
S I VW + T V + GH+ + +SPDG + TG D T+R W++
Sbjct: 1566 SDGNIAVWDLHNQTLVRQFQGHTDGASCIDISPDGTKLWTGGLDNTVRSWDL 1411
Score = 28.9 bits (63), Expect = 4.3, Method: Compositional matrix adjust.
Identities = 12/40 (30%), Positives = 22/40 (55%)
Frame = -3
Query: 348 AKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKT 387
A+LT + LA+SPDG+ + D + W++ ++T
Sbjct: 1644 AELTSSAPACYALAISPDGKVCFSCCSDGNIAVWDLHNQT 1525
Score = 28.5 bits (62), Expect = 5.8, Method: Compositional matrix adjust.
Identities = 38/167 (22%), Positives = 67/167 (40%)
Frame = -3
Query: 218 RRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKAIAWSPH 277
R+ QGH + S D L +GG DN + W+ +QQ+ + + + ++ + P
Sbjct: 1518 RQFQGHTDGASCIDISPDGTKLWTGGLDNTVRSWDLREGRQLQQH-DFSSQIFSLGYCPT 1342
Query: 278 QHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNLAWSKHANELVSTHGYSQNQIL 337
L G + + Q S V +L ++ VST N +
Sbjct: 1341 GEWLAV---GMESSNVEVLHHSKPDKYQLHLHESCVLSLKFAYCGKWFVSTG--KDNLLN 1177
Query: 338 VWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVF 384
W+ P + + + S VL ++ D + IVTG+GD+ + V
Sbjct: 1176 AWRTPYGASIFQ-SKESSSVLSCDIAADDKYIVTGSGDKKATLYEVI 1039
>26107
Length = 1338
Score = 35.4 bits (80), Expect = 0.037, Method: Compositional matrix adjust.
Identities = 59/256 (23%), Positives = 96/256 (37%), Gaps = 36/256 (14%)
Frame = -3
Query: 164 VQIWDAAAGKKLSMLEGHTARVGALAW---NAEQLSSGSRDRMILQRDIRTPPLQSERRL 220
V +WD K++ GH V ++A + Q +SG+RD I+ D R + +R
Sbjct: 1015 VALWDVETTTKVTTFIGHKCSVRSVASCPSSPAQCASGARDGHIMLWDSR---VNKKREH 845
Query: 221 QGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAA--------VKAI 272
Q Q HQ+ G+ +K P + H AA +++
Sbjct: 844 QPCSQV---------HQVCPQSGHQSK----------PAKHRRIHRAAGPKGVMDTQQSV 722
Query: 273 AWSPHQHGLLASGGGTADRCIRFW-------NTLTG--QPLQCIDTGSQV---------C 314
+Q L G D C++ W NT T P+ D + C
Sbjct: 721 TCVLYQTDNLIISSGANDGCVKMWDTRKWYTNTTTSLPVPVHTFDYPGHMRRLKGIVTMC 542
Query: 315 NLAWSKHANELVSTHGYSQNQILVWKYPSLTQVAK-----LTGHSYRVLYL--AMSPDGE 367
W + VS Y+ N+ V++Y Q + GH ++ A+SPDG+
Sbjct: 541 MDPWK--SQLFVS---YTDNK--VYRYQLAGQYREPQEYVYAGHRNDTFFVRCAISPDGK 383
Query: 368 AIVTGAGDETLRFWNV 383
+++G+G T W V
Sbjct: 382 YLLSGSGRNTGVIWEV 335
Score = 30.8 bits (68), Expect = 0.97, Method: Compositional matrix adjust.
Identities = 22/81 (27%), Positives = 35/81 (43%), Gaps = 1/81 (1%)
Frame = -3
Query: 219 RLQGHRQEVCGLKW-STDHQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKAIAWSPH 277
R H V W S D Q L + G D + +W+ + + V + H +V+++A P
Sbjct: 1102 RWXAHNNAVFDYSWISNDSQCLTASG-DQTVALWDVETTTKVTTFIGHKCSVRSVASCPS 926
Query: 278 QHGLLASGGGTADRCIRFWNT 298
ASG D I W++
Sbjct: 925 SPAQCASGA--RDGHIMLWDS 869
>01462
Length = 995
Score = 35.4 bits (80), Expect = 0.041, Method: Compositional matrix adjust.
Identities = 27/111 (24%), Positives = 49/111 (44%), Gaps = 12/111 (10%)
Frame = +2
Query: 164 VQIWDAAAGKKLSMLEGHTARVGALAW--NAEQLSSGSRDRMILQRDIRTPPLQSERRLQ 221
+ +WD AG+ L+ +EGH + + +A++ S S D + DIR+ ++ L+
Sbjct: 269 IHVWDIEAGQYLNAMEGHKDYIHKVVMKNDAQECVSASEDGTVRMWDIRS-STETVHCLE 445
Query: 222 GHRQEVCG----------LKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQY 262
+ E+C L + L GG KL W+ +L+P +
Sbjct: 446 PSKNELCSRPLLGKWLRCLALDPEEGWLVCGGGP-KLSAWHLRTLAPTTIF 595
Score = 32.3 bits (72), Expect = 0.34, Method: Compositional matrix adjust.
Identities = 18/68 (26%), Positives = 32/68 (47%)
Frame = +2
Query: 330 GYSQNQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKTRS 389
G +I VW + + + GH + + M D + V+ + D T+R W++ RS
Sbjct: 251 GAGDRKIHVWDIEAGQYLNAMEGHKDYIHKVVMKNDAQECVSASEDGTVRMWDI----RS 418
Query: 390 TKESVSVL 397
+ E+V L
Sbjct: 419 STETVHCL 442
>37142
Length = 327
Score = 35.0 bits (79), Expect = 0.057, Method: Compositional matrix adjust.
Identities = 27/104 (25%), Positives = 51/104 (49%), Gaps = 12/104 (11%)
Frame = +2
Query: 238 LLASGGNDNKLLVWNHSSL------SPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTADR 291
++ G ++ +LV++ + V Q T+H AVKA+ ++P Q LLASG ++
Sbjct: 2 VIVGGADNGSVLVYSAQKMIDGDADCSVLQLTKHTGAVKALDFNPFQTNLLASGASESE- 178
Query: 292 CIRFW------NTLTGQPLQCIDTGSQVCNLAWSKHANELVSTH 329
I W N +T P Q +V +AW++ +++++
Sbjct: 179 -IYIWDLNKPDNPMT--PGQKSQPPEEVSCVAWNRQVQHILASN 301
>31054
Length = 392
Score = 34.7 bits (78), Expect = 0.068, Method: Compositional matrix adjust.
Identities = 16/51 (31%), Positives = 30/51 (58%)
Frame = -2
Query: 332 SQNQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWN 382
S + + WK+P + L+GH+ + LA++ DG +V+GA + T+ W+
Sbjct: 355 SPDXVKQWKFPDGNFIQNLSGHNAIINTLAVNSDG-VLVSGADNGTMHLWD 206
>12140
Length = 727
Score = 34.7 bits (78), Expect = 0.078, Method: Compositional matrix adjust.
Identities = 30/106 (28%), Positives = 46/106 (43%), Gaps = 9/106 (8%)
Frame = +2
Query: 158 GTHKGFVQIW--DAAAGKKLSMLEGHTARVGALAWNA------EQLSSGSRD-RMILQRD 208
G V+IW D + LEGH+ V +AW ++S S+D R+I+ +
Sbjct: 278 GGCDNLVKIWREDETGWVEDQKLEGHSDWVRDVAWAPSIGLPRNVIASCSQDCRVIIWTN 457
Query: 209 IRTPPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHS 254
+ + R L V + WS +LA G DNK+ +W S
Sbjct: 458 DGSSNQWTSRILNKFSDVVWHVSWSVTGNILAVSGGDNKVTLWKES 595
>21921
Length = 1341
Score = 33.9 bits (76), Expect = 0.12, Method: Compositional matrix adjust.
Identities = 19/77 (24%), Positives = 37/77 (48%)
Frame = -1
Query: 262 YTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNLAWSKH 321
Y H V++I P L++ G+ D IRFW +G+ ++ + G V ++AW+ +
Sbjct: 495 YKGHTGIVRSICPDPTGQWLVS---GSDDGTIRFWEVSSGRCMKTLQVGGCVTSVAWNPN 325
Query: 322 ANELVSTHGYSQNQILV 338
+ V + +L+
Sbjct: 324 PSLCVVAATLNTTVLLI 274
Score = 33.5 bits (75), Expect = 0.16, Method: Compositional matrix adjust.
Identities = 16/41 (39%), Positives = 23/41 (56%)
Frame = -1
Query: 345 TQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFS 385
TQ GH+ V + P G+ +V+G+ D T+RFW V S
Sbjct: 510 TQALVYKGHTGIVRSICPDPTGQWLVSGSDDGTIRFWEVSS 388
>34511
Length = 1037
Score = 33.5 bits (75), Expect = 0.16, Method: Compositional matrix adjust.
Identities = 16/38 (42%), Positives = 22/38 (57%)
Frame = +3
Query: 350 LTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKT 387
L GH RV L ++ +G ++ TG+ D LR WN S T
Sbjct: 60 LAGHDNRVSCLGVTENGMSVATGSWDSFLRVWN*VSCT 173
>21105
Length = 650
Score = 33.1 bits (74), Expect = 0.23, Method: Compositional matrix adjust.
Identities = 14/41 (34%), Positives = 25/41 (60%)
Frame = +1
Query: 347 VAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKT 387
+ + H V LA+ P+G +++G+ D ++R WN+ SKT
Sbjct: 169 IHAMVAHLDSVTSLAVDPNGLYLLSGSHDCSIRLWNLDSKT 291
Score = 28.5 bits (62), Expect = 4.5, Method: Compositional matrix adjust.
Identities = 21/74 (28%), Positives = 33/74 (44%), Gaps = 4/74 (5%)
Frame = +1
Query: 220 LQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYTEHLA----AVKAIAWS 275
+ H V L + L SG +D + +WN S + VQ+ T H ++ +A+
Sbjct: 178 MVAHLDSVTSLAVDPNGLYLLSGSHDCSIRLWNLDSKTCVQEITSHRKKFDESIHDVAFH 357
Query: 276 PHQHGLLASGGGTA 289
P Q +AS G A
Sbjct: 358 P-QKPYIASAGADA 396
>19140
Length = 573
Score = 32.7 bits (73), Expect = 0.24, Method: Compositional matrix adjust.
Identities = 13/38 (34%), Positives = 24/38 (63%)
Frame = -3
Query: 346 QVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNV 383
++ KL GH+ V L ++ DG ++G+ D T+R W++
Sbjct: 511 KLMKLKGHTDNVKALVLNRDGTQCLSGSSDGTIRLWSL 398
>15337
Length = 860
Score = 32.7 bits (73), Expect = 0.27, Method: Compositional matrix adjust.
Identities = 15/49 (30%), Positives = 26/49 (53%)
Frame = -1
Query: 338 VWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSK 386
V+ Y S+ + + + +L + SPDG+ IVTG D+ + W+ K
Sbjct: 251 VFNYNSMELIGTMKSYFGGLLCVCWSPDGKYIVTGGEDDLVTVWSFHEK 105
Score = 28.1 bits (61), Expect = 7.2, Method: Compositional matrix adjust.
Identities = 13/46 (28%), Positives = 23/46 (50%)
Frame = -1
Query: 232 WSTDHQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKAIAWSPH 277
WS D + + +GG D+ + VW+ V + H + V +A+ H
Sbjct: 179 WSPDGKYIVTGGEDDLVTVWSFHEKRVVCRGHGHKSWVNVVAFDIH 42
>15118
Length = 1074
Score = 32.7 bits (73), Expect = 0.30, Method: Compositional matrix adjust.
Identities = 29/123 (23%), Positives = 54/123 (43%), Gaps = 4/123 (3%)
Frame = +3
Query: 265 HLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQ----PLQCIDTGSQVCNLAWSK 320
H++ V+ +A+ LL + GG D I+FW + L+ + + + +
Sbjct: 189 HVSGVRGVAFDAFN-CLLITAGGDCD--IKFWRFGSRDRARVLLKELKMSEGISRILLHR 359
Query: 321 HANELVSTHGYSQNQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRF 380
+N L + V +L V +GHS + L+ S DG ++T + D T+R
Sbjct: 360 DSNMLAVV--LEDFTVSVIDVDTLRVVRVFSGHSNSITDLSFSGDGRWLITASMDCTVRT 533
Query: 381 WNV 383
W++
Sbjct: 534 WSL 542
>15972
Length = 1069
Score = 32.7 bits (73), Expect = 0.30, Method: Compositional matrix adjust.
Identities = 14/33 (42%), Positives = 20/33 (60%)
Frame = +3
Query: 350 LTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWN 382
+GH V +LA+ P G+ +T + D TLR WN
Sbjct: 225 FSGHKGPVRHLAVHPSGKLTLTVSQDRTLRLWN 323
>01584
Length = 1540
Score = 32.3 bits (72), Expect = 0.33, Method: Compositional matrix adjust.
Identities = 17/51 (33%), Positives = 27/51 (52%), Gaps = 1/51 (1%)
Frame = -2
Query: 295 FWNTLTGQPLQCIDTGSQVCNLAW-SKHANELVSTHGYSQNQILVWKYPSL 344
FW +TG+ L C VC W +HA ++S H S+ ++ ++PSL
Sbjct: 678 FWLIITGKHLACTRGNHGVCLAPW*REHAVAVLSHHARSKVRVTSCQHPSL 526
>36111
Length = 687
Score = 32.3 bits (72), Expect = 0.35, Method: Compositional matrix adjust.
Identities = 20/71 (28%), Positives = 32/71 (45%), Gaps = 1/71 (1%)
Frame = +2
Query: 121 TPEKKGLFTVTRLCDLSVEG-DSVTSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLE 179
T + K F R+ + S+E V +V + N A G G+V IWD K+L
Sbjct: 170 TFKTKYAFKCHRIKEDSLEKIYPVNAVAFHNVYNTFATGGSDGYVNIWDGFHKKRLCXFH 349
Query: 180 GHTARVGALAW 190
+ + +LA+
Sbjct: 350 RYPTSIASLAF 382
>21025
Length = 444
Score = 32.3 bits (72), Expect = 0.38, Method: Compositional matrix adjust.
Identities = 13/41 (31%), Positives = 24/41 (58%)
Frame = +1
Query: 14 VIQNENTMPRVTEMRRTLTPASSPVSSPSKHGDRFIPSRAG 54
V++ ++T+ ++ + L P+ SPV +KHG +I S A
Sbjct: 127 VLRQQHTVDTISRLMLVL*PSYSPVCQHAKHGKLYIISMAA 249
>11493
Length = 535
Score = 31.2 bits (69), Expect = 0.74, Method: Compositional matrix adjust.
Identities = 38/163 (23%), Positives = 68/163 (41%), Gaps = 6/163 (3%)
Frame = -2
Query: 223 HRQEVCGLKWSTDHQLLASGGNDNKLLVWNHS---SLSPVQQYT--EHLAAVKAIAWSPH 277
H + VC + S + + +GG + VW+ S + +PV Q + ++++ P
Sbjct: 480 HGEVVCAVTISNPTKYVYTGGK-GCVKVWDISQPGNKNPVSQLDCLQRDNYIRSVKLLPD 304
Query: 278 QHGLLASGGGTADRCIRFWNTLTGQP-LQCIDTGSQVCNLAWSKHANELVSTHGYSQNQI 336
L+ GG A + W+ + P ++ T + A + + V S I
Sbjct: 303 GRTLIV--GGEASN-LSIWDLASPTPRIKAELTSAAPACYALAISPDSKVCFSCCSDGNI 133
Query: 337 LVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLR 379
VW + V + GH+ + +SPDG + TG D T+R
Sbjct: 132 AVWDLHNEILVRQFQGHTDGASCIDISPDGSRLWTGGLDNTVR 4
>27270
Length = 1078
Score = 30.8 bits (68), Expect = 0.90, Method: Compositional matrix adjust.
Identities = 25/91 (27%), Positives = 40/91 (43%), Gaps = 6/91 (6%)
Frame = +2
Query: 221 QGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKAIAWSPHQHG 280
+GH + V + W D + L S D ++ WN ++L ++++ A S HG
Sbjct: 263 KGHSKAVTDMCWRADGRTLYSSSLDGHVIGWNVNTLHMIEKWK---------ATSGRHHG 415
Query: 281 L----LASGGG--TADRCIRFWNTLTGQPLQ 305
+ L S TAD I+ W+ T LQ
Sbjct: 416 VHCVCLCSSSRLLTADHTIKMWDLTTKNVLQ 508
>27681
Length = 465
Score = 30.8 bits (68), Expect = 0.93, Method: Compositional matrix adjust.
Identities = 12/31 (38%), Positives = 19/31 (61%)
Frame = +2
Query: 357 VLYLAMSPDGEAIVTGAGDETLRFWNVFSKT 387
V A +P + + +G+GD T R WN+ S+T
Sbjct: 2 VFICAWNPTNDLLASGSGDSTARIWNMTSET 94
Score = 30.8 bits (68), Expect = 1.0, Method: Compositional matrix adjust.
Identities = 10/25 (40%), Positives = 18/25 (72%)
Frame = +2
Query: 143 VTSVGWSERGNLVAVGTHKGFVQIW 167
VTS+ W+ G L+A G++ G+ ++W
Sbjct: 170 VTSLDWNSEGTLLATGSYDGYARLW 244
Score = 29.3 bits (64), Expect = 2.7, Method: Compositional matrix adjust.
Identities = 14/44 (31%), Positives = 21/44 (47%)
Frame = +3
Query: 219 RLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQY 262
R R + LKW+ + S G D ++W+ SS S QQ+
Sbjct: 270 RWVNTRAPIFALKWNKRGNYILSAGVDKTTIIWDASSGSCTQQF 401
>10162
Length = 1629
Score = 30.8 bits (68), Expect = 0.99, Method: Compositional matrix adjust.
Identities = 20/88 (22%), Positives = 42/88 (47%), Gaps = 2/88 (2%)
Frame = +3
Query: 302 QPLQCIDTGSQVCNLAWSKHANELVSTHGYSQNQILVWKYPS--LTQVAKLTGHSYRVLY 359
Q + + GS + L W A+ L++ G ++ +W+ PS +++ L H L
Sbjct: 3 QQIWSYECGSDITWLQWHGGAHVLLA--GTQGGEVWLWQVPSQDYSKMKMLQSHGQPSLC 176
Query: 360 LAMSPDGEAIVTGAGDETLRFWNVFSKT 387
+ P+G+ + G D ++ W++ + T
Sbjct: 177 GKILPNGKYVCVGYSDGVVKLWDLKTGT 260
Score = 28.9 bits (63), Expect = 3.4, Method: Compositional matrix adjust.
Identities = 18/65 (27%), Positives = 30/65 (46%), Gaps = 4/65 (6%)
Frame = +3
Query: 141 DSVTSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNAEQ----LS 196
+ V + WS L+ G +++WDA +G ++L GH L ++ + L
Sbjct: 645 EGVCKLQWSSSTALLYTACLDGVMRVWDARSGASKAVLTGHARNSCILDFDVTRDGTCLV 824
Query: 197 SGSRD 201
SGS D
Sbjct: 825 SGSED 839
>07665
Length = 435
Score = 30.8 bits (68), Expect = 1.1, Method: Compositional matrix adjust.
Identities = 30/102 (29%), Positives = 43/102 (42%), Gaps = 14/102 (13%)
Frame = -2
Query: 167 WDAAAGKKLSMLEGHTARVGALAWNAEQLSSGSRDRMILQR--DIRTPPLQSERRLQGHR 224
WD GK L LE H + AL + S +R + + I+ L ++ ++ R
Sbjct: 392 WDLNDGKNLYTLE-HNDIINALCF------SPNRYWLCVAYGPSIKIWDLACKKTVEELR 234
Query: 225 QEVCG------------LKWSTDHQLLASGGNDNKLLVWNHS 254
EV L WSTD Q L +G +DN + VW S
Sbjct: 233 PEVVSPTSKAEQPQCLSLAWSTDGQTLFAGYSDNTIRVWQVS 108
Score = 28.9 bits (63), Expect = 3.5, Method: Compositional matrix adjust.
Identities = 12/28 (42%), Positives = 16/28 (57%)
Frame = -2
Query: 356 RVLYLAMSPDGEAIVTGAGDETLRFWNV 383
+ L LA S DG+ + G D T+R W V
Sbjct: 194 QCLSLAWSTDGQTLFAGYSDNTIRVWQV 111
>28289
Length = 349
Score = 29.3 bits (64), Expect = 2.7, Method: Composition-based stats.
Identities = 24/86 (27%), Positives = 41/86 (47%), Gaps = 5/86 (5%)
Frame = -1
Query: 170 AAGKKLSM---LEGHTARVGALAWNA--EQLSSGSRDRMILQRDIRTPPLQSERRLQGHR 224
AA LSM LEGH+ V +AWN ++L++ + +I+ + E ++
Sbjct: 277 AAPSNLSMNQSLEGHSGAVQVVAWNEHHQKLTTSDQYGLIIVWMLYKGSWYEEMINNRNK 98
Query: 225 QEVCGLKWSTDHQLLASGGNDNKLLV 250
V G+KW+ D Q + D ++V
Sbjct: 97 SVVRGMKWTADGQKICIVYEDGAVIV 20
>16199
Length = 694
Score = 28.9 bits (63), Expect = 3.8, Method: Compositional matrix adjust.
Identities = 17/63 (26%), Positives = 31/63 (49%), Gaps = 3/63 (4%)
Frame = +2
Query: 132 RLCDLSVEGDSV---TSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGAL 188
++CD S G SV T + G + A GT ++IWD ++ +GH V ++
Sbjct: 44 KVCDKS--GPSVPALTCAQFHPDGLIFATGTEDSVIKIWDLKERANVANFQGHQGPVTSI 217
Query: 189 AWN 191
+++
Sbjct: 218 SFS 226
>30679
Length = 1025
Score = 28.9 bits (63), Expect = 4.0, Method: Compositional matrix adjust.
Identities = 12/38 (31%), Positives = 19/38 (50%)
Frame = +1
Query: 238 LLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKAIAWS 275
+L S G D K +VWN PV H + +++W+
Sbjct: 4 ILLSAGFDYKCVVWNVEQAEPVNIVDCHTDTIFSMSWN 117
Score = 28.9 bits (63), Expect = 4.1, Method: Compositional matrix adjust.
Identities = 13/61 (21%), Positives = 33/61 (54%), Gaps = 2/61 (3%)
Frame = +1
Query: 166 IWDAAAGKKLSMLEGHTARVGALAWN--AEQLSSGSRDRMILQRDIRTPPLQSERRLQGH 223
+W+ + +++++ HT + +++WN ++ S+D+ + D RT + +E Q H
Sbjct: 40 VWNVEQAEPVNIVDCHTDTIFSMSWNRXGSMFATTSKDKKLRTIDPRTTTVAAES--QCH 213
Query: 224 R 224
+
Sbjct: 214 K 216
>12841
Length = 1364
Score = 28.5 bits (62), Expect = 4.5, Method: Compositional matrix adjust.
Identities = 12/29 (41%), Positives = 17/29 (58%)
Frame = +1
Query: 142 SVTSVGWSERGNLVAVGTHKGFVQIWDAA 170
+V V WS R + V H+G V++WD A
Sbjct: 1183 TVHDVCWSPRSSTVFACVHEGAVEVWDLA 1269
>17602
Length = 481
Score = 28.5 bits (62), Expect = 4.7, Method: Compositional matrix adjust.
Identities = 18/67 (26%), Positives = 29/67 (43%), Gaps = 5/67 (7%)
Frame = +3
Query: 143 VTSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWN-----AEQLSS 197
V+ V +S G + T +++WD + GK L GH + N + + S
Sbjct: 192 VSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYVGHRNEKYCIFANFSVTGGKWIVS 371
Query: 198 GSRDRMI 204
GS D M+
Sbjct: 372 GSEDNMV 392
Score = 28.1 bits (61), Expect = 6.0, Method: Compositional matrix adjust.
Identities = 13/38 (34%), Positives = 22/38 (57%)
Frame = +3
Query: 357 VLYLAMSPDGEAIVTGAGDETLRFWNVFSKTRSTKESV 394
V ++ SP+G+ I+ D TL+ W+ +SK + K V
Sbjct: 192 VSFVKFSPNGKYILAATLDNTLKLWD-YSKGKCLKTYV 302
>00105
Length = 1426
Score = 28.5 bits (62), Expect = 4.8, Method: Compositional matrix adjust.
Identities = 10/28 (35%), Positives = 16/28 (57%)
Frame = +3
Query: 277 HQHGLLASGGGTADRCIRFWNTLTGQPL 304
H HG+ G + +RC+ L+GQP+
Sbjct: 1131 HNHGVFVGRGYSLERCMVLCGVLSGQPM 1214
>30297
Length = 822
Score = 28.5 bits (62), Expect = 5.2, Method: Compositional matrix adjust.
Identities = 30/119 (25%), Positives = 44/119 (36%), Gaps = 18/119 (15%)
Frame = -3
Query: 213 PLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWN--------HSSLSPVQQYTE 264
P ++ GH+++V + LLA+ D +++VWN H P YT+
Sbjct: 733 PYWADDERDGHKEDVLAVAHCLP-NLLATASYDGEVIVWNMVSGHIFCHLRPPPPADYTD 557
Query: 265 H----------LAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQV 313
L +K A+ L+ASG I WN G L G QV
Sbjct: 556 QSLDGDLGISKLLFLKTRAYKKDAGSLVASGPRAH---IHIWNVFQGGRLMAQFPGVQV 389
>30108
Length = 1032
Score = 28.5 bits (62), Expect = 5.3, Method: Compositional matrix adjust.
Identities = 43/176 (24%), Positives = 69/176 (39%), Gaps = 13/176 (7%)
Frame = +1
Query: 223 HRQEVCGLKWSTDHQLLASGGNDNKLLV-WNHSSLSPVQQYTEHLAAVKAIAWSPHQHGL 281
H V W A DN + V ++ S+L PV ++ +V +AW P +
Sbjct: 97 HESPVRAFAWHPHTTKFALALQDNSVHVHYSASTLVPVLKHKLQ-KSVAHLAWQPLSASV 273
Query: 282 LASGGGTADRCIRFWN----TLTGQP----LQCIDTGSQ--VCNLAWSKHANELVSTHGY 331
LA +A + W+ +L +P +Q + + +LAW AN L+S
Sbjct: 274 LAVACQSA---VLIWHIEPTSLAARPSSSSVQVLQHSGHCPITHLAWLPSANILLSASPV 444
Query: 332 SQNQILVWKY--PSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFS 385
++ W + T + L G V LA SPDG ++ R W+ S
Sbjct: 445 -DTAVMAWSVGGEACTALRYLGGGG--VSLLACSPDGSKVMAATPATLFRVWDTTS 603
>38177
Length = 430
Score = 28.1 bits (61), Expect = 5.9, Method: Compositional matrix adjust.
Identities = 17/71 (23%), Positives = 34/71 (47%), Gaps = 2/71 (2%)
Frame = +3
Query: 230 LKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTA 289
L W+ + + L +G + + +WN + + H +V+A+ WS H ++ TA
Sbjct: 6 LAWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDVSVRAMRWSNHDQWMV-----TA 170
Query: 290 DRC--IRFWNT 298
D I++W +
Sbjct: 171 DHSGYIKYWQS 203
>31500
Length = 739
Score = 27.3 bits (59), Expect = 9.9, Method: Compositional matrix adjust.
Identities = 11/32 (34%), Positives = 17/32 (53%)
Frame = -1
Query: 290 DRCIRFWNTLTGQPLQCIDTGSQVCNLAWSKH 321
DRC+ FWN +T + ++C+ AW H
Sbjct: 241 DRCVTFWNYMTPN-INLPYNKRKICSRAWGTH 149
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000364898 | hsapiens_gene_ensembl |
Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase).
[Source:Uniprot/SWISSPROT;Acc:P43405]
(635 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
06405 196 2e-50
21808 194 1e-49
14477 182 3e-46
09007 173 2e-43
11780 100 7e-41
04852 139 4e-33
07291 129 4e-30
14116 129 4e-30
20640 125 5e-29
17300 115 9e-27
07940 117 2e-26
22005 93 1e-24
18996 103 2e-22
08294 98 1e-20
17637 84 2e-16
18921 82 8e-16
01707 80 3e-15
13305 79 8e-15
00715 78 8e-15
17253 77 3e-14
01718 75 8e-14
13066 69 9e-12
19301 67 2e-11
01756 66 3e-11
12721 66 4e-11
14420 65 7e-11
09606 65 1e-10
21079 63 3e-10
18484 62 1e-09
00300 61 1e-09
01060 60 2e-09
14126 60 2e-09
13212 60 3e-09
31885 59 9e-09
19094 57 3e-08
04591 56 4e-08
29581 55 7e-08
12672 54 1e-07
17806 54 2e-07
27546 50 2e-06
25550 49 2e-06
19761 50 4e-06
07833 50 4e-06
26560 49 6e-06
30755 49 6e-06
27405 47 2e-05
01966 47 3e-05
03240 47 3e-05
15910 46 5e-05
07836 46 5e-05
26711 46 5e-05
28157 45 8e-05
04138 45 1e-04
01392 44 2e-04
11228 43 4e-04
12786 42 6e-04
11185 42 7e-04
10546 41 0.002
30231 40 0.003
13840 39 0.007
21433 38 0.012
04627 38 0.014
35671 38 0.015
00394 37 0.024
18881 36 0.040
18481 36 0.047
31489 35 0.064
31789 35 0.10
14257 34 0.20
26009 34 0.23
16708 33 0.32
38046 33 0.38
21210 32 0.53
36481 32 0.54
15741 32 0.58
18401 32 0.75
00191 32 1.1
29590 31 1.4
25019 31 1.8
02638 30 2.1
37602 30 2.7
07933 30 4.0
14799 30 4.4
>06405
Length = 1965
Score = 196 bits (498), Expect = 2e-50, Method: Compositional matrix adjust.
Identities = 107/286 (37%), Positives = 169/286 (59%), Gaps = 5/286 (1%)
Frame = +1
Query: 350 SPYADPEEIRPKEVYLDRKLLTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEAN 409
SP D EI E+ + +L G G +G V + + K+ K VAVK LK +
Sbjct: 226 SPEPDRWEIERTEIAMKHRL--------GGGQYGDVYEAMW--KRYNKIVAVKTLKEDTM 375
Query: 410 DPALKDELLAEANVMQQLDNPYIVRMIGICEAES-WMLVMEMAELGPLNKYLQQNRHVKD 468
AL D L EA +M+++ +P +V+++G+C E + +V E G L YL+ + ++
Sbjct: 376 --ALND-FLEEAAIMKEMKHPNLVQLLGVCTREPPFYIVTEFMPHGNLLDYLRSS--TRE 540
Query: 469 KN----IIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADEN 524
+N ++ + Q++ GM YLE NF+HRDLAARN L+ + K++DFGL++ ++ D
Sbjct: 541 ENGPTALMYMATQIASGMAYLETKNFIHRDLAARNCLVADSNMVKVADFGLARLMKDDT- 717
Query: 525 YYKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAM 584
Y A K+P+KW APE + + +FS++SD+W+FGVL+WE +YG PY G++ +EV +
Sbjct: 718 -YTAHIGAKFPIKWTAPEGLAFNRFSTRSDIWAFGVLLWELATYGMSPYPGVELTEVYHL 894
Query: 585 LEKGERMGCPAGCPREMYDLMNLCWTYDVENRPGFAAVELRLRNYY 630
LE+G RM P G P ++Y LM CW +D ++RP F + L N +
Sbjct: 895 LERGYRMERPPGTPADVYILMLKCWQWDPKDRPTFKEIHFLLENMF 1032
Score = 52.4 bits (124), Expect = 5e-07, Method: Compositional matrix adjust.
Identities = 29/75 (38%), Positives = 43/75 (57%)
Frame = +1
Query: 201 GSYALCLLHEGKVLHYRIDKDKTGKLSIPEGKKFDTLWQLVEHYSYKADGLLRVLTVPCQ 260
G ++ + EG+V HYRI +D GK+ + + +F+TL +LV H+S ADGL+ L P
Sbjct: 19 GQRSISVRFEGRVYHYRITEDD-GKVFVTQEHRFNTLAELVHHHSIHADGLVTTLLYPAP 195
Query: 261 KIGTQGNVNFGGRPQ 275
K Q FG P+
Sbjct: 196 K--RQKPTVFGVSPE 234
Score = 32.0 bits (71), Expect = 0.87, Method: Compositional matrix adjust.
Identities = 25/84 (29%), Positives = 40/84 (47%), Gaps = 5/84 (5%)
Frame = +1
Query: 43 QSRNYLGGFALSVAHGRKAHHYTIERELNGTYAIAGGRTHASPADLCHYHSQESDGLVCL 102
+S + G ++SV + +HY I E +G + + A+L H+HS +DGLV
Sbjct: 1 ESESSPGQRSISVRFEGRVYHYRIT-EDDGKVFVTQEHRFNTLAELVHHHSIHADGLVTT 177
Query: 103 LKKPFNRPQ-----GVQPKTGPFE 121
L P + Q GV P+ +E
Sbjct: 178 LLYPAPKRQKPTVFGVSPEPDRWE 249
>21808
Length = 1011
Score = 194 bits (492), Expect = 1e-49, Method: Compositional matrix adjust.
Identities = 92/221 (41%), Positives = 146/221 (66%), Gaps = 2/221 (0%)
Frame = +1
Query: 399 VAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRMIGIC-EAESWMLVMEMAELGPLN 457
VA+K LK+ DP + LAEA +M++L +P ++++ +C + + ++ E+ + G L
Sbjct: 28 VAIKTLKSGTMDP---KDFLAEAQIMKKLRHPKLIQLYAVCTQDDPIFIITELMKNGSLL 198
Query: 458 KYLQ-QNRHVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLS 516
++LQ + R +K +I++ Q++ GM YLE N++HRDLAARN+L+ + KI+DFGL+
Sbjct: 199 EFLQGKGRVLKLPALIDIGAQIACGMAYLESQNYIHRDLAARNILVSDNNTVKIADFGLA 378
Query: 517 KALRADENYYKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGM 576
+ ++ DE Y+A+ ++P+KW APE NY +F+ KSDVWSFG+L+ E +YG+ PY GM
Sbjct: 379 RVIKEDE--YEARVGARFPIKWTAPEAANYNRFTIKSDVWSFGILLTETVTYGRVPYPGM 552
Query: 577 KGSEVTAMLEKGERMGCPAGCPREMYDLMNLCWTYDVENRP 617
+EV +E G RM CP GCP+ +YD+M CW + RP
Sbjct: 553 TNAEVLHQVEHGYRMPCPPGCPKPLYDIMLECWRKEEMERP 675
>14477
Length = 493
Score = 182 bits (463), Expect = 3e-46, Method: Compositional matrix adjust.
Identities = 86/160 (53%), Positives = 125/160 (78%)
Frame = -1
Query: 370 LTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQLDN 429
+ +++ +LG+GNFG+V KG ++ VA+K+LKN DP+++ EL+ EA VM+++D+
Sbjct: 487 IQMDELKLGAGNFGSVMKGVCRLDDREIPVAIKVLKNADLDPSVQSELIKEAEVMKKMDH 308
Query: 430 PYIVRMIGICEAESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSMGMKYLEESN 489
+IVR+IG+CE E+ MLV+E+A+LGPLNK+L +N+H+ NI+EL+ QVS GM+YLE +
Sbjct: 307 MHIVRLIGLCEGETMMLVLELAKLGPLNKFLPKNKHLPLWNILELMWQVSQGMEYLEANK 128
Query: 490 FVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQ 529
FVHRDLAARN+LL +H+AKISDFG+SK L + NYY AQ
Sbjct: 127 FVHRDLAARNILLCDEHFAKISDFGMSKTLSRENNYYMAQ 8
>09007
Length = 1440
Score = 173 bits (438), Expect = 2e-43, Method: Compositional matrix adjust.
Identities = 102/265 (38%), Positives = 150/265 (56%), Gaps = 13/265 (4%)
Frame = -1
Query: 375 KELGSGNFGTVKKGYYQMKKVVKT-VAVKILKNEANDPALKD--ELLAEANVMQQLDNPY 431
K LG G+FGTV++ + + K VAVK L + D KD E L E +MQ LD+
Sbjct: 861 KSLGQGHFGTVRQAIWTAESGEKVQVAVKCL---SKDKIHKDGQEFLKETAIMQMLDHEN 691
Query: 432 IVRMIGICEAESWMLVMEMAELGPLNKYLQQNRHVKDK------NIIELVHQVSMGMKYL 485
IVR+ G+ ++ +M + EL P+ L+ + V + + + QV GM YL
Sbjct: 690 IVRVYGVV-MDNGADIMLVTELAPMRSLLECVKEVSARVDFSVPRLCDFSQQVCDGMSYL 514
Query: 486 EESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQ--THGKWPVKWYAPEC 543
E VHRDLAARN+LL ++ KISD G+S AL A + YY++Q H + V W APE
Sbjct: 513 ESKRLVHRDLAARNILLFSKSKVKISDVGVSGALGAGKEYYQSQQTIHLQNAVAWCAPES 334
Query: 544 INYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLE--KGERMGCPAGCPREM 601
FSS SDVW+FGVL+WE F++G +P+ G+ G ++ ++ + +R+ P CP+E
Sbjct: 333 FRNLCFSSASDVWAFGVLLWEFFTHGFQPWAGLNGQQIMEAVDAPQSQRLEQPDLCPKEY 154
Query: 602 YDLMNLCWTYDVENRPGFAAVELRL 626
Y +M CW + + RP F+ + L L
Sbjct: 153 YAVMLKCWEQEPQRRPTFSQLFLTL 79
>11780
Length = 1713
Score = 99.8 bits (247), Expect(2) = 7e-41, Method: Compositional matrix adjust.
Identities = 65/170 (38%), Positives = 91/170 (53%), Gaps = 2/170 (1%)
Frame = +3
Query: 377 LGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRMI 436
+G G+FG V KG Y+ + VA+K LK++ + L EA+VM L + +VR+I
Sbjct: 621 IGKGDFGDVYKGMYRGQ----PVAIKQLKDKDRG---EQSFLQEASVMTSLRHDNLVRLI 779
Query: 437 GICEAESWMLVMEMAELGPLNKYLQQNRH--VKDKNIIELVHQVSMGMKYLEESNFVHRD 494
G+ E+ LV E G L +YL+ + K+ I M+YLE VHRD
Sbjct: 780 GVVLGETIFLVTEFMGKGNLVEYLRSRGRSVITKKDQINFATDTCAAMEYLESKRLVHRD 959
Query: 495 LAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECI 544
LAARNVL+ AK+SDFGL+K +QT K+P+KW APE +
Sbjct: 960 LAARNVLVHDDGKAKVSDFGLAKFGDF------SQTSVKFPIKWTAPEAL 1091
Score = 86.7 bits (213), Expect(2) = 7e-41, Method: Compositional matrix adjust.
Identities = 38/81 (46%), Positives = 53/81 (65%)
Frame = +1
Query: 548 KFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAGCPREMYDLMNL 607
KF+SKSD+WSFG+L+WE +S+G+ PY + ++V +E+G RM P GCP E+Y +M
Sbjct: 1102 KFTSKSDMWSFGILLWEIYSFGRVPYPRIPLTDVVMHVERGYRMEAPEGCPPEIYSIMKQ 1281
Query: 608 CWTYDVENRPGFAAVELRLRN 628
W D RP F +V RL N
Sbjct: 1282 AWELDPNERPTFKSVLARLNN 1344
Score = 81.6 bits (200), Expect = 8e-16, Method: Compositional matrix adjust.
Identities = 50/107 (46%), Positives = 64/107 (59%), Gaps = 1/107 (0%)
Frame = +3
Query: 166 MPWFHGKISREESEQIVLIGSKTNGKFLIRARDNN-GSYALCLLHEGKVLHYRIDKDKTG 224
MPWFHGKI+R+++E+ L+ + +G FLIR N G Y LC+ H GKV HYRI +
Sbjct: 249 MPWFHGKITRQQAEE--LLKPREDGLFLIRESSNYPGDYTLCVCHLGKVEHYRILY-REN 419
Query: 225 KLSIPEGKKFDTLWQLVEHYSYKADGLLRVLTVPCQKIGTQGNVNFG 271
+L+I E F L +LV+HY ADGL LT P K G NFG
Sbjct: 420 QLTIDEEGFFRNLDELVKHYLADADGLCTQLTRPVTKQGG----NFG 548
Score = 53.5 bits (127), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 43/133 (32%), Positives = 65/133 (48%), Gaps = 1/133 (0%)
Frame = +3
Query: 13 LPFFFGNITREEAEDYLVQGGMSDGLYLLRQSRNYLGGFALSVAHGRKAHHYTI-ERELN 71
+P+F G ITR++AE+ L DGL+L+R+S NY G + L V H K HY I RE
Sbjct: 249 MPWFHGKITRQQAEELLKP--REDGLFLIRESSNYPGDYTLCVCHLGKVEHYRILYRENQ 422
Query: 72 GTYAIAGGRTHASPADLCHYHSQESDGLVCLLKKPFNRPQGVQPKTGPFEDLKENLIREY 131
T G + +L ++ ++DGL L +P V + G F + ++E+
Sbjct: 423 LTIDEEG--FFRNLDELVKHYLADADGLCTQLTRP------VTKQGGNFGTVS---LQEF 569
Query: 132 VKQTWNLQGQALE 144
W + Q LE
Sbjct: 570 KSGGWVIAXQDLE 608
>04852
Length = 1462
Score = 139 bits (350), Expect = 4e-33, Method: Compositional matrix adjust.
Identities = 85/255 (33%), Positives = 132/255 (51%), Gaps = 32/255 (12%)
Frame = +1
Query: 398 TVAVKILKNEANDPALKDELLAEANVMQQL----DNPYIVRMIGICE--AESWMLVMEMA 451
TVAVK+L++ +D + E VM+ + + IV +G C W++V E A
Sbjct: 25 TVAVKMLRDIVTAVEEQD-FVQELQVMKAVKKMGSHINIVNFLGCCTQGGPLWVIV-EFA 198
Query: 452 ELGPLNKYLQQNRH-------------------------VKDKNIIELVHQVSMGMKYLE 486
+ G L +L+ R ++ KN++ Q++ GM++L
Sbjct: 199 KNGNLRDFLESCRDGINGYGKFVSPQDPGWYTKTPGGHVIRRKNLLSYAFQIARGMEFLA 378
Query: 487 ESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINY 546
+HRDLAARNVL+ +H KI+DFGLS+ +YYK ++ G+ PVKW APE +
Sbjct: 379 SRKCIHRDLAARNVLVTEEHVLKIADFGLSRT----GDYYKKRSGGRLPVKWMAPEALFD 546
Query: 547 YKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEV-TAMLEKGERMGCPAGCPREMYDLM 605
++++KSDVWSFGV++WE FS G PY + E+ + +L+ RM P +Y +M
Sbjct: 547 MRYTTKSDVWSFGVVLWEIFSLGGMPYASIPNEELYSKLLDDAYRMPRPELASGNLYAIM 726
Query: 606 NLCWTYDVENRPGFA 620
CW +RP F+
Sbjct: 727 ERCWLNRPSDRPEFS 771
>07291
Length = 833
Score = 129 bits (324), Expect = 4e-30, Method: Compositional matrix adjust.
Identities = 59/159 (37%), Positives = 94/159 (59%)
Frame = +1
Query: 471 IIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQT 530
+++ Q++ GM YL+E VHR+LAARN ++ ++SD+G++ +L Y +
Sbjct: 55 LLDFGRQIADGMAYLQEVKVVHRNLAARNCIVTEDGRLQLSDYGVTGSLFPQSYYTADDS 234
Query: 531 HGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGER 590
+ VKW APE I+ + FSSKSDVW+FGV++WE + G PY ++ S + L++G R
Sbjct: 235 PARDLVKWMAPETIDNFHFSSKSDVWAFGVVLWELLTRGITPYPDVENSSLLPYLKEGHR 414
Query: 591 MGCPAGCPREMYDLMNLCWTYDVENRPGFAAVELRLRNY 629
M P P +Y++M CW E RP FA + +L+ +
Sbjct: 415 MKKPKQSPEPVYEMMTACWNESPEQRPDFAELNDQLKTF 531
>14116
Length = 1017
Score = 129 bits (323), Expect = 4e-30, Method: Compositional matrix adjust.
Identities = 77/217 (35%), Positives = 119/217 (54%), Gaps = 5/217 (2%)
Frame = -1
Query: 358 IRPKEVYLDRKLLTLEDKELGSGNFGTVKKGYYQM--KKVVKTVAVKILKNEANDPALKD 415
I + + +DR+ LT+ +E+G GNFG VK+G+ + +K VAVK L N
Sbjct: 666 IENESLLIDREFLTM-GEEIGKGNFGCVKRGFLTLPEQKGDILVAVKTLHNNNPREIELQ 490
Query: 416 ELLAEANVMQQLDNPYIVRMIGICEAESWM--LVMEMAELGPLNKYLQQNRHVKD-KNII 472
L EA +M+ + ++ +IGIC M +V+ + G L Y++ ++H K++I
Sbjct: 489 SFLQEALIMKDFHHSNVLTLIGICLNLDDMPLVVLPFMKHGDLLTYIRDDQHQPTIKDLI 310
Query: 473 ELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHG 532
++ GM YL FVHRDLAARN +L + K++DFGL++ + E Y
Sbjct: 309 MYGVDIARGMDYLAGLKFVHRDLAARNCMLDEDFHVKVADFGLARDIYEKEYYSSENKKA 130
Query: 533 KWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYG 569
K PVKW A E + + SK+DVWS+GV++WE + G
Sbjct: 129 KLPVKWMALESLEKGNYDSKTDVWSYGVVLWELLTRG 19
>20640
Length = 1492
Score = 125 bits (314), Expect = 5e-29, Method: Compositional matrix adjust.
Identities = 58/139 (41%), Positives = 84/139 (60%)
Frame = +1
Query: 490 FVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINYYKF 549
+VHRDLA RN L+ KISDFGL++++ + +YY+ H P++W E I Y KF
Sbjct: 7 YVHRDLATRNCLVGHDLVVKISDFGLARSVHS-VDYYRGSEHDAIPIRWMPLEAILYNKF 183
Query: 550 SSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAGCPREMYDLMNLCW 609
S++SDVWSFGV++WE F++ +PY G+ EV +++G+ + CP P MY+LM CW
Sbjct: 184 STQSDVWSFGVVLWEIFAFALQPYYGLTHEEVVRFVKEGKVLACPERTPPPMYELMKQCW 363
Query: 610 TYDVENRPGFAAVELRLRN 628
RP F + L N
Sbjct: 364 HRRPATRPSFHTLHKTLEN 420
>17300
Length = 480
Score = 115 bits (287), Expect(2) = 9e-27, Method: Compositional matrix adjust.
Identities = 57/116 (49%), Positives = 76/116 (65%), Gaps = 2/116 (1%)
Frame = +1
Query: 478 VSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRAD--ENYYKAQTHGKWP 535
+S GM L + +VHRDLAARN+L+ K++DFGLS+ + +D E Y + GK P
Sbjct: 1 ISSGMGXLADMGYVHRDLAARNILVNEILVCKVADFGLSREIESDTTEGAYTTK-GGKIP 177
Query: 536 VKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERM 591
V+W APE I Y KF+S SDVWSFGV+MWE SYG++PY +V +EKG R+
Sbjct: 178 VRWTAPEAIAYRKFTSASDVWSFGVVMWEVMSYGERPYWNWSNQDVIKAVEKGYRL 345
Score = 23.9 bits (50), Expect(2) = 9e-27, Method: Composition-based stats.
Identities = 10/32 (31%), Positives = 16/32 (50%), Gaps = 1/32 (3%)
Frame = +2
Query: 592 GCPA-GCPREMYDLMNLCWTYDVENRPGFAAV 622
CP+ CP ++ LM W + +RP + V
Sbjct: 341 ACPSMDCPEALHQLMLDAWQKERSHRPKMSMV 436
>07940
Length = 1336
Score = 117 bits (292), Expect = 2e-26, Method: Compositional matrix adjust.
Identities = 53/105 (50%), Positives = 75/105 (71%)
Frame = -3
Query: 469 KNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKA 528
K++I +QV+ GM+YL +HRDLAARNVL+ ++ KI+DFGL++ L+ +YY+
Sbjct: 347 KDLISYAYQVARGMEYLASKQCIHRDLAARNVLVAEEYVLKIADFGLTRNLQ-QFDYYRK 171
Query: 529 QTHGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPY 573
T G+ PVKW APE + K++SKSDVWS+GVL+WE F+ G PY
Sbjct: 170 TTDGRLPVKWMAPEALFDRKYTSKSDVWSYGVLLWEIFTLGGNPY 36
>22005
Length = 873
Score = 93.2 bits (230), Expect(2) = 1e-24, Method: Compositional matrix adjust.
Identities = 74/244 (30%), Positives = 118/244 (48%), Gaps = 54/244 (22%)
Frame = +1
Query: 375 KELGSGNFGTVKK-GYYQMKKVVKTVAV--------KILKNEANDPALKDELLAEANVMQ 425
+++G G FG V K + + +V + K+LK +A++ L+ + EA++M
Sbjct: 1 RDIGQGAFGRVSKLKFLGLASLVGELIPEKRP*LL*KMLKEDASED-LQSDFEREASLMA 177
Query: 426 QLDNPYIVRMIGICEAESWM-LVMEMAELGPLNKYLQ--------------QNRHV---- 466
D+P IV+++G+C M L+ E G LN +L+ QN V
Sbjct: 178 DFDHPNIVKLLGVCAIGKPMCLLFEFMSKGDLNDFLRLCSPENYNLPVSRSQNLVVDLED 357
Query: 467 ------------KD--------------KNIIELVHQVSMGMKYLEESNFVHRDLAARNV 500
KD K+ + + Q+S GM YL + ++VHRDLA R V
Sbjct: 358 GLRVEVEAEECEKDTQSEDRDCSGMLXTKDQLYISQQISAGMAYLAQKDYVHRDLATRTV 537
Query: 501 LLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFGV 560
+ ISDFGL++++ + +YY+ P++W E I Y KFS++SDVWSFGV
Sbjct: 538 X-SRTT*S*ISDFGLARSVHS-VDYYRGSEQDAIPIRWMPLEAILYSKFSTQSDVWSFGV 711
Query: 561 LMWE 564
++WE
Sbjct: 712 VLWE 723
Score = 38.5 bits (88), Expect(2) = 1e-24, Method: Compositional matrix adjust.
Identities = 16/53 (30%), Positives = 28/53 (52%)
Frame = +3
Query: 566 FSYGQKPYRGMKGSEVTAMLEKGERMGCPAGCPREMYDLMNLCWTYDVENRPG 618
F++ +PY G+ EV ++ G+ + P P ++Y+LM CW + RP
Sbjct: 726 FAFALQPYYGLTHEEVVNYVKAGKILEQPTKTPHQVYELMKQCW----QRRPA 872
>18996
Length = 491
Score = 103 bits (257), Expect = 2e-22, Method: Compositional matrix adjust.
Identities = 60/137 (43%), Positives = 79/137 (57%), Gaps = 5/137 (3%)
Frame = +2
Query: 491 VHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINYYKFS 550
+HRDLAARN+L V + KISDFGL++ AD YY + P+KWY+PE I KFS
Sbjct: 2 IHRDLAARNIL-VDRSCVKISDFGLAQFANAD-GYYYGISQRDIPIKWYSPEAIETCKFS 175
Query: 551 SKSDVWSFGVLMWEAFSYGQKPY----RGMKGSEVTAMLEKGERMGCPAGCPREMY-DLM 605
S SDVWS+GV ++E FS G+ P + E L KGER+ P C +Y +LM
Sbjct: 176 SYSDVWSYGVTLFEMFSRGEIPNLLPGHDLTQEEFLNRLRKGERLPKPELCSDFVYSELM 355
Query: 606 NLCWTYDVENRPGFAAV 622
CW ++RP F +
Sbjct: 356 RPCWHEMPKSRPTFHQI 406
>08294
Length = 1849
Score = 97.8 bits (242), Expect = 1e-20, Method: Compositional matrix adjust.
Identities = 66/218 (30%), Positives = 96/218 (44%), Gaps = 13/218 (5%)
Frame = +2
Query: 430 PYIVRMIGIC-EAESWMLVMEMAELGPLNKYLQQNRHVKDK------------NIIELVH 476
P IV +G+C EAE L+ E + G L ++L R+ + + +
Sbjct: 887 PNIVHFMGVCREAEPHFLITEYCDWGDLKQFLLATRNDNGRGRGTRVPALALSQKLGMGQ 1066
Query: 477 QVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPV 536
QV+ GM+ L VH DLAARNVLL ++ K++ LS + A E Y Q P+
Sbjct: 1067 QVAAGMEALSNQGLVHGDLAARNVLLTSRMQLKVARPALSGDVYASEYYPLHQR--LVPL 1240
Query: 537 KWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAG 596
+W PE + ++ DVW+FGV +WE PYR M EV L+ +
Sbjct: 1241 RWLPPEGVLEDSATTCGDVWAFGVFLWEVLQLADLPYRLMSDEEVLRSLQHSQAALDSPD 1420
Query: 597 CPREMYDLMNLCWTYDVENRPGFAAVELRLRNYYYDVV 634
P + L+ C RP F+ + L DVV
Sbjct: 1421 APPALLSLLQRCTAQQPSQRPPFSEICSVLSLASTDVV 1534
>17637
Length = 447
Score = 84.0 bits (206), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 43/137 (31%), Positives = 73/137 (53%), Gaps = 1/137 (0%)
Frame = +1
Query: 499 NVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKW-PVKWYAPECINYYKFSSKSDVWS 557
N ++ Q K++D LS+ L + + Y G++ P+KW + E + ++ SDVWS
Sbjct: 1 NCVIDDQLRVKLTDSALSRDLFSGD--YNCLGDGEYRPIKWLSLEALQKSHYNEGSDVWS 174
Query: 558 FGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAGCPREMYDLMNLCWTYDVENRP 617
FGVLMWE + G+ PY + E+ L+ G R+ P CP E++ +M CW RP
Sbjct: 175 FGVLMWEMCTLGKLPYAEIDPYEMEHYLKDGYRLAQPFNCPDELFTIMAYCWASMPAERP 354
Query: 618 GFAAVELRLRNYYYDVV 634
F+ +++ L ++ +
Sbjct: 355 SFSQLQICLSEFHTQIT 405
>18921
Length = 697
Score = 81.6 bits (200), Expect = 8e-16, Method: Compositional matrix adjust.
Identities = 57/192 (29%), Positives = 101/192 (52%), Gaps = 3/192 (1%)
Frame = +2
Query: 376 ELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRM 435
+LG G++G+V K ++ +T V +K D L+ E++ E ++MQQ D+ YIV+
Sbjct: 50 KLGEGSYGSVFKSLHK-----ETGQVLAIKQVPVDTDLQ-EIIKEISIMQQCDSKYIVKY 211
Query: 436 IG--ICEAESWMLVMEMAELGPLNKYLQ-QNRHVKDKNIIELVHQVSMGMKYLEESNFVH 492
G + W +VME G ++ ++ +N+ + ++ I +++ G+ YL +H
Sbjct: 212 YGSYFKNTDLW-IVMEYCGAGSVSDIMRLRNKTLVEREIATILYYTLKGLXYLHSRRKIH 388
Query: 493 RDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINYYKFSSK 552
RD+ A N+LL + +AK++DFG++ L + K T P W APE I +
Sbjct: 389 RDIKAGNILLNNEGHAKLADFGVAGQLT--DTMAKRNTVIGTPY-WMAPEVIQEIGYDCV 559
Query: 553 SDVWSFGVLMWE 564
+D+WS G+ E
Sbjct: 560 ADIWSLGITALE 595
>01707
Length = 757
Score = 79.7 bits (195), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 51/214 (23%), Positives = 105/214 (49%), Gaps = 2/214 (0%)
Frame = +1
Query: 376 ELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRM 435
++G G++G V K + K+ + VA+K +DP +K + E +++QL +P +VR+
Sbjct: 85 KIGEGSYGVVFKC--RNKETSQLVAIKKFVESEDDPLIKKIAMREIRMLKQLKHPNLVRL 258
Query: 436 IGICEAESWM-LVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSMGMKYLEESNFVHRD 494
I + + + LV + + LN+ + R + + + +++Q + + + + N +HRD
Sbjct: 259 IEVFRRKKRLHLVFDYVDHTLLNELDRYPRGLPEPMVKRIIYQTLLAVNFCHQYNTIHRD 438
Query: 495 LAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPE-CINYYKFSSKS 553
+ N+L+ Q K+ DFG ++ L + Y +W + APE + ++
Sbjct: 439 VKPENILITRQGQVKLCDFGFARILTGPGDEYTDYVATRW---YRAPELLVGDTQYGPPV 609
Query: 554 DVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEK 587
DVW+ G + E + GQ + G + ++ K
Sbjct: 610 DVWAIGCVFAELLT-GQALWPGRSDVDQLHLIRK 708
>13305
Length = 549
Score = 78.6 bits (192), Expect = 8e-15, Method: Composition-based stats.
Identities = 34/98 (34%), Positives = 54/98 (55%)
Frame = +2
Query: 535 PVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCP 594
P++W A E + ++++SDVWSFGV++WE F+ G PY ++ A L+ G R+ P
Sbjct: 14 PIRWMAVESLFNNTYTTQSDVWSFGVVLWEIFTLGGTPYSSTDTQQLFAFLKDGYRLKRP 193
Query: 595 AGCPREMYDLMNLCWTYDVENRPGFAAVELRLRNYYYD 632
C + Y +M CW + + RP F + RL+ D
Sbjct: 194 KLCDQNTYAMMLQCWNENAQRRPTFPELCGRLQRMLDD 307
>00715
Length = 1788
Score = 78.2 bits (191), Expect = 8e-15, Method: Compositional matrix adjust.
Identities = 73/259 (28%), Positives = 112/259 (43%), Gaps = 38/259 (14%)
Frame = +1
Query: 397 KTVAVKILKNEANDP-ALK----DELLAEANVMQQLDNPYIVRMIGIC-----EAESWML 446
+TVAVKI +++P AL+ +ELLA ++ ++ +V ++G E +W+
Sbjct: 1 RTVAVKIYHKRSSNPRALRQSYSNELLAFRCGLRHVN---VVSILGATSLHRFEDGAWL- 168
Query: 447 VMEMAELGPLNKYLQQNRHVKDKNI---IELVHQVSMGMKYLEESNFVHRDLAARNVLLV 503
M +GPLN N H +D + + L Q++ G+ YL N VH DL N LL
Sbjct: 169 --AMEYVGPLNLQTILNDHQQDIDSSMRLSLALQMARGLHYLHSINIVHLDLKPANCLLT 342
Query: 504 TQHYAKISDFGLSKALR-------------ADENYYKAQTHGKW------PVKWYAPECI 544
+I+DFG L A G W + + APE +
Sbjct: 343 RDLKLRIADFGCCHQLTPTGLDMGEREGGMAGNELELTPVQGAWKNELAGTLAYRAPELL 522
Query: 545 NYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAGC----PRE 600
+ S +SDV+S G+ +W+ + Q PY G+ V + + CP P E
Sbjct: 523 KGLQPSVRSDVYSLGITLWQMCTR-QGPYEGVPAHAVVYQVVSKDLRPCPPPSTEDDPFE 699
Query: 601 MY--DLMNLCWTYDVENRP 617
+ DL CW VE+RP
Sbjct: 700 VMFRDLYTQCWARRVEDRP 756
>17253
Length = 483
Score = 76.6 bits (187), Expect = 3e-14, Method: Composition-based stats.
Identities = 48/155 (30%), Positives = 82/155 (52%), Gaps = 14/155 (9%)
Frame = -1
Query: 398 TVAVKILKNEANDPALKDELLAEANVMQQLD-NPYIVRMIGICE-AESWMLVMEMAELGP 455
TVAVK NEA A K E L E ++M++L +P +V +G C ++ +++ME G
Sbjct: 462 TVAVKT-HNEAATDAEKSEFLRELSIMRKLPRHPNVVSFMGCCTMSDPALILMEFCCHGD 286
Query: 456 LNKYLQQNR------------HVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLV 503
L +L++ R + ++ V+ GM ++ + VHRD+AARNVL+
Sbjct: 285 LLSFLRKRRPDRTVFLTSTANDLTARDFFSFALHVARGMAHVANNKIVHRDVAARNVLIS 106
Query: 504 TQHYAKISDFGLSKALRADENYYKAQTHGKWPVKW 538
++ K+SDFGLS+ + + Y+ + P++W
Sbjct: 105 ERNVCKVSDFGLSRRVGDQNDVYEIVSRRPLPLRW 1
>01718
Length = 959
Score = 75.1 bits (183), Expect = 8e-14, Method: Compositional matrix adjust.
Identities = 67/265 (25%), Positives = 128/265 (48%), Gaps = 16/265 (6%)
Frame = +3
Query: 375 KELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVR 434
+++G+G F V K +++ V +A+K+ +N + +L E ++ +L + I+R
Sbjct: 165 EKIGAGFFSEVFKVTHRITGQV--MALKMNTMTSN----RHNMLREVQLLNRLQHANILR 326
Query: 435 MIGICEAESWM-LVMEMAELGPLNKYLQQNRHVKDKNI-----IELVHQVSMGMKYLEES 488
+G+C E + + E G L + L++ KD+ + I+L ++ G+ YL +
Sbjct: 327 FMGVCVHEGQLHALTEYIPSGNLEQLLEK----KDEELPWTQRIQLTLGLARGLDYLHST 494
Query: 489 NFVHRDLAARNVLLVTQ----HYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECI 544
F+HRDL ++N+L+ + ++A I+DFGL+ + + K T G W APE +
Sbjct: 495 RFIHRDLTSKNILIRREDNHGYHAVIADFGLATKIPDPLDKEKLPTVGS--PYWMAPEVL 668
Query: 545 NYYKFSSKSDVWSFGVLMWEAFSY-----GQKPYRGMKGSEVTAMLEKGERMGCPAGCPR 599
N + ++ ++D++S G++M E + P G + A+ E + CP
Sbjct: 669 NGHFYNERADLFSVGIIMCEITARIPADPDIMPRMNNFGVDYVALSEM------ISYCPL 830
Query: 600 EMYDLMNLCWTYDVENRP-GFAAVE 623
+ L C D + RP G +E
Sbjct: 831 DYLQLAFKCCQVDPQKRPRGVEIIE 905
>13066
Length = 551
Score = 68.6 bits (166), Expect = 9e-12, Method: Compositional matrix adjust.
Identities = 52/182 (28%), Positives = 86/182 (47%), Gaps = 5/182 (2%)
Frame = +3
Query: 383 GTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLA-EANVMQQLDNPYIVRMIGICE- 440
GT GY + K+ A KI+ E ++ E +++ +LD+PYI+++ I +
Sbjct: 24 GTFNDGYGRNIKL----ACKIIDKEKAPVDFVEKFFPRELDLLTKLDHPYIIQIHSILQR 191
Query: 441 AESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNV 500
+ M AE G L Y+Q+ VK+K +Q++ + YL + HRDL N+
Sbjct: 192 XPKNFIFMRFAERGDLLTYIQEVGFVKEKQAKIWFYQMTTALNYLHSYDVAHRDLKCENI 371
Query: 501 LLVTQHYAKISDFGLSKAL--RADENYYKAQTHGKWPVKWYAPECINYYKFSSK-SDVWS 557
LL + K++DFG + A + E Y G + APE + ++ K +D WS
Sbjct: 372 LLSSHFNVKLADFGFACACITESGEKYMSRTYCGS--AAYAAPEIVYGAPYAPKVADAWS 545
Query: 558 FG 559
G
Sbjct: 546 LG 551
>19301
Length = 712
Score = 67.0 bits (162), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 43/143 (30%), Positives = 73/143 (51%), Gaps = 3/143 (2%)
Frame = +2
Query: 377 LGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANV--MQQLDNPYIVR 434
LGSG G V G K + VAVK +++ + E ++ +++L++P I+
Sbjct: 329 LGSGAQGAVFLG----KLCAEEVAVKKVRD-----------IKETDIRNLRKLNHPNIIS 463
Query: 435 MIGIC-EAESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSMGMKYLEESNFVHR 493
G+C +A + ++ME G L + L+ + + +++ Q++ GM YL +HR
Sbjct: 464 FKGVCTQAPCYCIIMEYCPYGQLYEVLRDGKEIPPALVLDWSKQIASGMNYLHSHKIIHR 643
Query: 494 DLAARNVLLVTQHYAKISDFGLS 516
DL + NVL+ KISDFG S
Sbjct: 644 DLKSPNVLVAKNDVVKISDFGTS 712
>01756
Length = 1858
Score = 66.2 bits (160), Expect = 3e-11, Method: Compositional matrix adjust.
Identities = 51/203 (25%), Positives = 91/203 (44%), Gaps = 11/203 (5%)
Frame = -3
Query: 376 ELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRM 435
++G G FG V K + KK + VA+K + + L E ++Q L++ +V +
Sbjct: 1721 KIGQGTFGEVFKA--RCKKTKQVVAMKKVLMDNEKEGFPITALREIKILQLLNHENVVDL 1548
Query: 436 IGICEAES---------WMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSMGMKYLE 486
I IC ++ + LV E E + I E++ Q+ G+ Y+
Sbjct: 1547 IEICSTKATSANRYKSMFYLVFEFCEHDLAGLLSNMSVVFNLPEIKEVMKQLMNGLYYIH 1368
Query: 487 ESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPE--CI 544
+ +HRD+ A N+L+ Q K++DFGL++A + T+ + WY P +
Sbjct: 1367 RNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTN-RVVTLWYRPPELLL 1191
Query: 545 NYYKFSSKSDVWSFGVLMWEAFS 567
+S+ D W G +M E ++
Sbjct: 1190 GDRNYSTAIDQWGAGCIMAEMWT 1122
>12721
Length = 821
Score = 66.2 bits (160), Expect = 4e-11, Method: Compositional matrix adjust.
Identities = 43/171 (25%), Positives = 76/171 (44%), Gaps = 7/171 (4%)
Frame = +1
Query: 414 KDELLAEANVMQQLDNPYIVRMIG--ICEAESWMLVMEMAELGPLNKYLQQNRHVKDKNI 471
++ L E VM+ +P IV M + E W +VME E G L + NR + + I
Sbjct: 208 RELLFNEVVVMRDYHHPNIVEMYNSYLVNDELW-VVMEFMEGGALTDIVTNNR-MDEVQI 381
Query: 472 IELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTH 531
+ + +L + +HRD+ + ++LL K+ DFG + D K+
Sbjct: 382 ATVCRACLKALAFLHANGVIHRDIKSDSILLSHDGKVKLXDFGFCAQVTQDLQKRKSLVG 561
Query: 532 GKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFS-----YGQKPYRGMK 577
+ W APE I+ + + D+WS G+++ E + + P + M+
Sbjct: 562 TPY---WMAPEVISRLPYGPEVDIWSLGIMVMEMIDAEPPFFNEPPLQAMR 705
>14420
Length = 528
Score = 65.5 bits (158), Expect = 7e-11, Method: Compositional matrix adjust.
Identities = 45/162 (27%), Positives = 78/162 (48%), Gaps = 2/162 (1%)
Frame = +2
Query: 414 KDELLAEANVMQQLDNPYIVRMIG--ICEAESWMLVMEMAELGPLNKYLQQNRHVKDKNI 471
K+ ++ E VM++ NP IV + + E W +VME G L + + + + I
Sbjct: 32 KELIINEILVMRENQNPNIVNYLDSYLVGEELW-VVMEFLAGGSLTDVVTET-CMDEGQI 205
Query: 472 IELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTH 531
+ + +++L E+ +HRD+ + N+LL K++DFG L +++ K T
Sbjct: 206 AAVCRECLQALEFLHENQVIHRDIKSDNILLGMDGSVKLTDFGFCAQLSPEQS--KRSTM 379
Query: 532 GKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPY 573
P W APE + ++ D+WS GV+ E G+ PY
Sbjct: 380 VGTP-YWMAPEVVTRKQYGPTVDIWSLGVMCIEMIE-GEPPY 499
>09606
Length = 1300
Score = 64.7 bits (156), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 55/221 (24%), Positives = 97/221 (43%), Gaps = 20/221 (9%)
Frame = -3
Query: 375 KELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVR 434
+ELG G + KG + K + VA+ ++ + E+ + + +P +V+
Sbjct: 1097 EELGKGEHSIIYKG--RRKGTINFVAIHCIEK-----CKRPEVTNTVRMTHDISHPNVVQ 939
Query: 435 MIGICEAESWM-LVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSMGMKYLEESNFVHR 493
E + + LV+E+ G L L Q+ H+ + +I + + G+ Y+ +
Sbjct: 938 FHEWYETSNHLWLVVELCTGGSLADILAQDHHLPETSIRDFGIHLVTGLHYIHSLGILFH 759
Query: 494 DLAARNVLLVTQHYAKISDFGLSKA--LRADENYYK-AQTHGKWPVK------------- 537
DL VLL T K +DFGLSK +E ++K A+ +W ++
Sbjct: 758 DLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQWNIQSAEEMMKQVPTSG 579
Query: 538 ---WYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRG 575
+ APE + S SD+W+ G + +E FS G P+ G
Sbjct: 578 SPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFS-GHPPFLG 459
>21079
Length = 878
Score = 63.2 bits (152), Expect = 3e-10, Method: Compositional matrix adjust.
Identities = 42/146 (28%), Positives = 75/146 (51%), Gaps = 3/146 (2%)
Frame = +1
Query: 443 SWMLVMEMAELGPL-NKYLQQNRHVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVL 501
+ +LVME G L + ++ + + +++ + V Q+ G+ Y+ + +H DL NVL
Sbjct: 46 TMVLVMEFVGAGELFERVIRDDFVLTERDCVHFVRQICSGVGYMHTQSILHLDLKPENVL 225
Query: 502 LVTQHY--AKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFG 559
V+ + KI DFGL++ + ++ Q P ++ APE +NY + + +D+WS G
Sbjct: 226 CVSDNSNQIKIIDFGLARFYKPGDSL---QVLFGTP-EFIAPEVVNYDEINFTTDMWSIG 393
Query: 560 VLMWEAFSYGQKPYRGMKGSEVTAML 585
V+ + S G+ S VT ML
Sbjct: 394 VICYILLS-------GLSPSRVTTML 450
>18484
Length = 635
Score = 61.6 bits (148), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 41/150 (27%), Positives = 75/150 (50%), Gaps = 1/150 (0%)
Frame = +1
Query: 460 LQQNRHVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSK-A 518
+QQ K+ ++++G+ +L + ++RDL NV+L ++ + KI+DFG+ K
Sbjct: 16 IQQEGKFKEPVAAFYAAEIAVGLFFLHDQGIIYRDLKLDNVMLDSEGHIKIADFGMCKEG 195
Query: 519 LRADENYYKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKG 578
+ D +T P + APE + Y +S D W++GVL++E + GQ P+ G
Sbjct: 196 MTGDAT---TRTFCGTP-DYIAPEIVLYQPYSKSVDWWAYGVLLFEMLA-GQPPFDGEDE 360
Query: 579 SEVTAMLEKGERMGCPAGCPREMYDLMNLC 608
E+ + + + P RE ++LC
Sbjct: 361 DELFSSITD-HNVSYPKAMSREA---VSLC 438
>00300
Length = 2318
Score = 61.2 bits (147), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 48/246 (19%), Positives = 106/246 (43%), Gaps = 5/246 (2%)
Frame = -1
Query: 376 ELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRM 435
++G G FG V + +A+K +K + ND E+ E + + + + +V+
Sbjct: 1637 KIGEGQFGKVYTAVNM--STGELMALKEMKFQPNDLQQLREMCDEIKIFEGIQHENLVKY 1464
Query: 436 IGI-CEAESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSMGMKYLEESNFVHRD 494
G+ + ++ ME + G + + + + + I ++ + + +L E++ VHRD
Sbjct: 1463 YGVEVHKDEMLMFMEYCDTGTIEEAAKMG--LPEYLIRRYTREIVLAVNHLHENSIVHRD 1290
Query: 495 LAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINYYK---FSS 551
+ N+ L + + K+ DFG S L++ + + APE +
Sbjct: 1289 IKGANIFLTSNGHVKLGDFGCSVKLKSHTTMPGEFHNLVGTTAYMAPEVFTQNDQGGYGR 1110
Query: 552 KSDVWSFGVLMWEAFSYGQKPYRGMKGS-EVTAMLEKGERMGCPAGCPREMYDLMNLCWT 610
+D+WS G ++ E + G++P+ + + ++ + G + P E ++L
Sbjct: 1109 AADIWSLGCVVIE-MATGKRPWHDLDNNYQIMYKVGIGHKPAVPDSLSVEGKHFLDLIMC 933
Query: 611 YDVENR 616
+D R
Sbjct: 932 HDPAQR 915
>01060
Length = 1800
Score = 60.5 bits (145), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 48/192 (25%), Positives = 93/192 (48%), Gaps = 5/192 (2%)
Frame = +1
Query: 375 KELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVR 434
+++G G +G V K + + + +A+K ++ ++ + + E ++++L + IV
Sbjct: 91 QKIGEGTYGVVYKCRH--RATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTNIVC 264
Query: 435 MIG-ICEAESWMLVMEMAELGPLNKYLQQNRH--VKDKNIIE-LVHQVSMGMKYLEESNF 490
+ I E E LV E + L Y+ + V D+ +++ V Q+ G+ + +
Sbjct: 265 LEDVIMEDERLFLVFEFLSMD-LKMYIDKFPEGVVLDRRLVKSYVFQIVTGIXFCHQRRI 441
Query: 491 VHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECI-NYYKF 549
VHRDL +N+L+ KI+DFG+++ Y + W + APE + K+
Sbjct: 442 VHRDLKPQNLLINHTGAIKIADFGMARTFALPVRAYTHEVVTLW---YRAPEILMGASKY 612
Query: 550 SSKSDVWSFGVL 561
S+ DVWS G +
Sbjct: 613 STPVDVWSIGTI 648
>14126
Length = 1265
Score = 60.5 bits (145), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 51/202 (25%), Positives = 103/202 (50%), Gaps = 11/202 (5%)
Frame = +3
Query: 377 LGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQLD---NPYIV 433
+G+G +GTV K ++ + VA+K ++ + + + E ++++QL+ +P +V
Sbjct: 213 IGNGAYGTVYKAR-DLRNQGEFVAMKRIRLNNTEEGMPMMAIREISMLKQLEQYEHPNVV 389
Query: 434 RMIG-----ICEAESWM-LVMEMAELGPLNKYLQQ--NRHVKDKNIIELVHQVSMGMKYL 485
R++ I + E + LV E E L YL + + + I +L+ Q+ G+ +L
Sbjct: 390 RLLDVSHNTITDREIRLNLVFEYIE-HDLATYLAKCPSPGLGPDRIKDLMLQLLNGVDFL 566
Query: 486 EESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECIN 545
+ VHRDL +N+L+ K++DFGL++ +++ A T + + +PE +
Sbjct: 567 HSNRIVHRDLKPQNLLISKDGRLKLADFGLARIY----SFHMALTTVVVTLWYRSPEVLM 734
Query: 546 YYKFSSKSDVWSFGVLMWEAFS 567
++ + D+WS G + E F+
Sbjct: 735 QAEYGTSVDIWSCGCIFAELFT 800
>13212
Length = 1067
Score = 59.7 bits (143), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 45/160 (28%), Positives = 70/160 (43%), Gaps = 9/160 (5%)
Frame = -1
Query: 470 NIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQ 529
I + H++ M + +L + +HRD+ A NVLL K++DFG+S + + K
Sbjct: 977 QICYVCHEMCMALDFLHRHHVIHRDIKAGNVLLTIDGEVKLADFGVSA--KNTQTQQKRD 804
Query: 530 THGKWPVKWYAPECI-------NYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVT 582
T P W APE + Y F K+D+WS GV + E F+ + P + M V
Sbjct: 803 TFIGTPY-WMAPEVVLCETLKDTPYDF--KADIWSLGVTLIE-FAQIEPPNKEMHPMRVL 636
Query: 583 AMLEKGE--RMGCPAGCPREMYDLMNLCWTYDVENRPGFA 620
+ K + + P + D + C D RP A
Sbjct: 635 IKIHKSDPPTLEKPKKWTKLFKDFIAKCLVKDPNLRPTAA 516
>31885
Length = 529
Score = 58.5 bits (140), Expect = 9e-09, Method: Compositional matrix adjust.
Identities = 42/170 (24%), Positives = 82/170 (48%), Gaps = 6/170 (3%)
Frame = -2
Query: 421 ANVMQQLDNPYIVRM-IGICEAESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVS 479
+++ +LD+P++V + + E +V+++ G L ++QQ ++ + + Q++
Sbjct: 519 VDMLTRLDHPFLVNLWYAFQDEEDLFMVVDLFLGGDLRYHMQQEVSFREDCVKFYLCQLA 340
Query: 480 MGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWY 539
+ + YL VHRD+ N+LL Q + ++DF ++ L DE T G P +
Sbjct: 339 LVLDYLRSQKIVHRDIKPDNILLDEQGHCHVTDFNIATQLEDDE--LATSTSGTRP--YM 172
Query: 540 APEC----INYYK-FSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAM 584
APE IN + + D WS GV ++E ++P+ + + M
Sbjct: 171 APEVYGVAINERRGYGFPVDWWSLGVSLFELLK-KRRPFSVHSNTSLHEM 25
>19094
Length = 898
Score = 56.6 bits (135), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 31/103 (30%), Positives = 54/103 (52%)
Frame = +1
Query: 462 QNRHVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRA 521
+N+ + ++ I +++ G+ YL +HRD+ A N+LL + +AK++DFG++ L
Sbjct: 37 RNKTLVEREIATILYYTLKGL*YLHSRRKIHRDIKAGNILLNNEGHAKLADFGVAGQL-- 210
Query: 522 DENYYKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWE 564
+ K T P W APE I + +D+WS G+ E
Sbjct: 211 TDTMAKRNTVIGTPY-WMAPEVIQEIGYDCVADIWSLGITALE 336
>04591
Length = 1117
Score = 56.2 bits (134), Expect = 4e-08, Method: Compositional matrix adjust.
Identities = 55/221 (24%), Positives = 96/221 (43%), Gaps = 14/221 (6%)
Frame = -2
Query: 418 LAEANVMQQLDNPYIVRMIGICEAE---------SWMLVMEMAE--LGPLNKYLQQNRHV 466
L E ++QQL++ +V++ IC + ++ L+ E + L L L+ +
Sbjct: 1077 LREIKILQQLEHENVVQLQEICHTQAGPYNRYKSTFYLIFEYCDYDLAGLLNNLRVKFSL 898
Query: 467 KDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYY 526
DK L+ Q+ G+ Y+ +HRD+ A N+LL K++DFGLS+ +
Sbjct: 897 ADKK--NLMSQLLNGLFYIHTKQILHRDIKAANILLTRDGVLKLADFGLSRP------WV 742
Query: 527 KAQTHGKWPVK-WYAPE--CINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTA 583
K++ V WY P + ++ + D+W G +M E +S +KP M+G
Sbjct: 741 KSKRLTNRVVTLWYRPPELLLGEREYGPEIDMWGVGCIMAEMWS--RKPL--MQGRSEQH 574
Query: 584 MLEKGERMGCPAGCPREMYDLMNLCWTYDVENRPGFAAVEL 624
L + +LC + + E PG +EL
Sbjct: 573 QLSL----------------ITDLCGSLNAEVWPGVTKLEL 499
>29581
Length = 1278
Score = 55.5 bits (132), Expect = 7e-08, Method: Compositional matrix adjust.
Identities = 44/135 (32%), Positives = 65/135 (48%), Gaps = 4/135 (2%)
Frame = -2
Query: 442 ESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVL 501
+S LVME E + + + +V Q+ G++YL E+ +HRDL N+L
Sbjct: 1130 DSLFLVMEYCEQDLASLLDNMPAPFSESQVKCIVLQLLKGLRYLHEAFIIHRDLKVSNLL 951
Query: 502 LVTQHYAKISDFGLSKALRADENYYKAQ--THGKWPVKWY-APECINYYKFSSKS-DVWS 557
+ + KI+DFGL++ NY K Q K WY APE + K S + D+WS
Sbjct: 950 MTDKGCVKIADFGLAR------NYGKPQKPMTPKVVTLWYRAPELLFGSKTHSTAIDMWS 789
Query: 558 FGVLMWEAFSYGQKP 572
G ++ E G KP
Sbjct: 788 AGCILGELL--GHKP 750
>12672
Length = 773
Score = 54.3 bits (129), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 43/177 (24%), Positives = 79/177 (44%), Gaps = 14/177 (7%)
Frame = +3
Query: 473 ELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFG-LSKALRADENYYKAQTH 531
++V + G++YL ++ VHRD+ N+LL +++ AK+ DF + A + + +
Sbjct: 3 KIVKGTASGIQYLNDNGHVHRDIKTANILLDSEYTAKVGDFATVVSAPSGEGKTVQNASV 182
Query: 532 GKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFS--YGQKPYRGMK--GSEVTAMLEK 587
+ APE I ++ S+K D +SFGV++ E + Q R + S + +E+
Sbjct: 183 VIGTAAYLAPEAI-HFDVSTKLDSYSFGVVLLEVITGLVAQDYSREERTLSSHIMENVEE 359
Query: 588 GERM---------GCPAGCPREMYDLMNLCWTYDVENRPGFAAVELRLRNYYYDVVN 635
E + P G ++YD+ C + RP + L +VN
Sbjct: 360 PEEIHDFVDQSAGTWPDGAVDKLYDISMRCLNLSKKQRPNVKDIRPELEEL*GCIVN 530
>17806
Length = 433
Score = 53.9 bits (128), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 43/123 (34%), Positives = 67/123 (54%), Gaps = 12/123 (9%)
Frame = +1
Query: 375 KELGSGNFGTVKKGYYQ--MKKVVKT-VAVKILKNEANDPALKDELLA---EANVMQQLD 428
KELG+G FG V + + V ++ V VK+LK D A KDE L E ++LD
Sbjct: 67 KELGTGWFGKVIESDAERITTGVSRSKVVVKMLK----DDATKDEQLLFFEEVAPFRELD 234
Query: 429 NPYIVRMIGIC-EAESWMLVMEMAELGPLNKYLQQNRH-----VKDKNIIELVHQVSMGM 482
+P IVR++G C E +++ME A LG L +YL+ +RH ++ +++ +S G+
Sbjct: 235 HPNIVRLLGQCTEMNPMLMLMECAALGNLKQYLRNHRHQQAMLIQKNRLLKFAMDISSGL 414
Query: 483 KYL 485
L
Sbjct: 415 ACL 423
>27546
Length = 426
Score = 50.4 bits (119), Expect = 2e-06, Method: Composition-based stats.
Identities = 26/102 (25%), Positives = 52/102 (50%), Gaps = 1/102 (0%)
Frame = -1
Query: 420 EANVMQQLDNPYIVRMIGICE-AESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQV 478
E ++ +LD+P I+++ I + + M AE G + ++++ + + Q+
Sbjct: 330 ELEILTRLDHPNIIQIHSILQRGPKIFIFMRYAEKGDMLSHIKKTGPIDEAQTKVWFFQM 151
Query: 479 SMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALR 520
+ ++YL + HRDL N+LL + KI+DFG ++ R
Sbjct: 150 AKALQYLHSHDIAHRDLKCENILLSKRLNVKIADFGFARYCR 25
>25550
Length = 941
Score = 49.3 bits (116), Expect(2) = 2e-06, Method: Compositional matrix adjust.
Identities = 23/58 (39%), Positives = 33/58 (56%)
Frame = +3
Query: 573 YRGMKGSEVTAMLEKGERMGCPAGCPREMYDLMNLCWTYDVENRPGFAAVELRLRNYY 630
Y G+ +EV +LE+G RM P G P ++Y LM CW +D + RP F + L N +
Sbjct: 42 YPGVDLTEVYHLLERGYRMERPQGTPADVYILMLKCWQWDPKERPTFKEIHYLLENMF 215
Score = 20.4 bits (41), Expect(2) = 2e-06, Method: Compositional matrix adjust.
Identities = 8/17 (47%), Positives = 10/17 (58%)
Frame = +1
Query: 559 GVLMWEAFSYGQKPYRG 575
GVL+WE +YG G
Sbjct: 1 GVLLWELATYGMSLTLG 51
>19761
Length = 473
Score = 49.7 bits (117), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 31/147 (21%), Positives = 69/147 (46%), Gaps = 2/147 (1%)
Frame = -3
Query: 468 DKNIIELVHQVSMGMKYLEESN--FVHRDLAARNVLLVTQHYAKISDFGLSKALRADENY 525
++ I+ + Q + + Y+ +HRDL +N+ + + ++ D GL++ L ++
Sbjct: 426 ERLIVCWLMQTASALNYMHTHTPVILHRDLKPQNIYVTEKGDVRLGDLGLARKLTGPADF 247
Query: 526 YKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAML 585
+Q + + +PE ++ ++SKSD+WS G + ++ G+K M + +
Sbjct: 246 ATSQVG---TIMYLSPEILSQQPYNSKSDIWSLGCVFYDI--TGKKGSDEMGVMFLLVQV 82
Query: 586 EKGERMGCPAGCPREMYDLMNLCWTYD 612
G ++ P +E D ++ T D
Sbjct: 81 MGGRKLPLPDHYSQEFRDTISRMLTKD 1
>07833
Length = 1504
Score = 49.7 bits (117), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 46/218 (21%), Positives = 94/218 (43%), Gaps = 8/218 (3%)
Frame = -3
Query: 413 LKDELLAEANVMQQLDNPYIVRMIGIC-EAESWMLVMEMAELGPLNKYLQ-QNRHVKDKN 470
+ + + E ++ ++P ++ ++ C + + +L+ + G L L ++ V D+N
Sbjct: 1490 ITRDFMEEFPRLRIFNHPNVLPVLACCNQPPNLVLISQFMPFGSLYNTLHGESGIVVDQN 1311
Query: 471 -IIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQ 529
+ ++ GM++L + N LL ++H + D L+ + + +
Sbjct: 1310 QSLRFAMDIARGMEFLHSM-----EPTIPNFLLTSKHV--MIDEDLTARINMADYCFSFH 1152
Query: 530 THGK-WPVKWYAPECINYYK---FSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAML 585
GK + W APE + + +D+WSF +LMWE + P+ + EV +
Sbjct: 1151 EKGKVYSPAWMAPEALQRRPDDINTRAADMWSFAILMWE-LETREVPFAELSSMEVGMKV 975
Query: 586 E-KGERMGCPAGCPREMYDLMNLCWTYDVENRPGFAAV 622
+G R+ P G M L+ +C + RP F +
Sbjct: 974 ALEGLRISIPPGISLHMSRLIKICMNEEPGKRPRFDMI 861
>26560
Length = 398
Score = 48.9 bits (115), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 32/120 (26%), Positives = 59/120 (49%), Gaps = 1/120 (0%)
Frame = -1
Query: 456 LNKYLQQNRHVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGL 515
L+ +L Q+ +K + +V +G++++ V+RDL N+LL + +ISD GL
Sbjct: 395 LHYHLSQHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGL 216
Query: 516 SKALRADENYYKAQTHGKWPVKWYAPECI-NYYKFSSKSDVWSFGVLMWEAFSYGQKPYR 574
+ + THG + APE + + S +D +SFG ++++ G P+R
Sbjct: 215 ACDFSKKRPHASVGTHG-----YMAPEVLMKGQSYDSSADWFSFGCMLYKLLK-GHSPFR 54
>30755
Length = 1137
Score = 48.9 bits (115), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 37/142 (26%), Positives = 61/142 (42%)
Frame = +2
Query: 477 QVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPV 536
++ + YL ++RDL N+LL + K++DFGL K D Y +
Sbjct: 56 EIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCK---EDITYGRTTKTFCGTP 226
Query: 537 KWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAG 596
++ APE ++ + D W GV+M+E G+ P+ + +V L E + P
Sbjct: 227 EYLAPEVLDDNDYGRAVDWWGTGVVMYEMIC-GRLPFYN-RDHDVLFTLILVEDVKFPRN 400
Query: 597 CPREMYDLMNLCWTYDVENRPG 618
E L++ D NR G
Sbjct: 401 ITDEAKSLLSGLLAKDPRNRLG 466
>27405
Length = 532
Score = 47.0 bits (110), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 35/150 (23%), Positives = 70/150 (46%), Gaps = 1/150 (0%)
Frame = -3
Query: 396 VKTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRMIGICEA-ESWMLVMEMAELG 454
+K + K +K + + +E + + V +P+IV M + E ++++ G
Sbjct: 476 MKCLDKKRIKMKGGETLALNERIMLSLVSTGEGSPFIVCMTYAFQTPEKLCFILDLMNGG 297
Query: 455 PLNKYLQQNRHVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFG 514
L+ +L Q+ +K + +V +G++++ V+RDL N+LL + +ISD G
Sbjct: 296 DLHYHLSQHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLG 117
Query: 515 LSKALRADENYYKAQTHGKWPVKWYAPECI 544
L+ + + THG + APE +
Sbjct: 116 LACDFSKKKPHASVGTHG-----YMAPEVL 42
>01966
Length = 1735
Score = 46.6 bits (109), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 40/169 (23%), Positives = 78/169 (46%), Gaps = 4/169 (2%)
Frame = -1
Query: 397 KTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRMIG-ICEAESWMLVMEMAELGP 455
+ +A+K ++ ++ + + E ++++L + IV + I E E LV E +
Sbjct: 1633 RKLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTNIVCLEDVIMEDERLFLVFEFLSMD- 1457
Query: 456 LNKYLQQNRH--VKDKNIIE-LVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISD 512
L Y+ + V D+ +++ V Q+ G+ + + VHRDL +N+L+ KI+D
Sbjct: 1456 LKMYIDKFPEGVVLDRRLVKSYVFQIVTGINFCHQRRIVHRDLKPQNLLINHTGAIKIAD 1277
Query: 513 FGLSKALRADENYYKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFGVL 561
FG+++ Y + W + APE + + S W+ G L
Sbjct: 1276 FGMARTFALPVRAYTHEVVTLW---YRAPEILMGPQ--STPPXWTCGAL 1145
>03240
Length = 1683
Score = 46.6 bits (109), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 48/187 (25%), Positives = 86/187 (45%), Gaps = 11/187 (5%)
Frame = -3
Query: 358 IRPKEVYLDRKLLTLEDKELGSGNFGTV---KKG----YYQMKKVVKTVAVKILKNEAND 410
IR K +D K + + K LG G FG V +K Y MK + K+ +K +N+
Sbjct: 1321 IRLKRAKMD-KCMFEKIKTLGVGAFGEVSLCRKNDTGMLYAMKTLRKSDVLK--RNQVAH 1151
Query: 411 PALKDELLAEANVMQQLDNPYIVRMIGICEAESWM-LVMEMAELGPLNKYLQQNRHVKDK 469
+ ++LAEA DN ++V++ + +++ VM+ G L L + + +
Sbjct: 1150 VKAERDILAEA------DNEWVVKLYYSFQDHNYLYFVMDYVPGGDLMGLLIRMEILDEP 989
Query: 470 NIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADEN---YY 526
V ++ ++ + F+HRD+ N+L+ + K++DFGL R N Y
Sbjct: 988 LARFYVAELVQAIESVHRMGFIHRDIKPDNILIDRNGHIKLTDFGLCTGFRWTHNSKYYQ 809
Query: 527 KAQTHGK 533
+ TH +
Sbjct: 808 RDGTHAR 788
>15910
Length = 1361
Score = 45.8 bits (107), Expect = 5e-05, Method: Compositional matrix adjust.
Identities = 34/125 (27%), Positives = 60/125 (48%), Gaps = 3/125 (2%)
Frame = +2
Query: 468 DKNIIELVHQVSMGMKYLEESNFVHRDLAARNVL---LVTQHYAKISDFGLSKALRADEN 524
+K+ + + G++Y+ + VHRDL N+L + K++DFGLS+ + E
Sbjct: 461 EKDAARAISDILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLADFGLSRII---EP 631
Query: 525 YYKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAM 584
+ T P + APE + K++ D+WS GV+ + G +P+ E+
Sbjct: 632 EVQMSTVCGTP-GYCAPEVLKGDKYTPSVDMWSVGVIAYILLC-GYEPFFAENEFEMYRK 805
Query: 585 LEKGE 589
+ KGE
Sbjct: 806 IIKGE 820
>07836
Length = 1478
Score = 45.8 bits (107), Expect = 5e-05, Method: Compositional matrix adjust.
Identities = 37/140 (26%), Positives = 66/140 (47%), Gaps = 18/140 (12%)
Frame = -1
Query: 443 SW---MLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSMGMKYLEESNF--------V 491
SW L+ + E G L+ YL +R + ++ L H G+ +L F
Sbjct: 1340 SWTQLFLITDYHENGSLHDYLL-SRVLDSSEMLALAHSAICGLAHLHIEIFGTRGKPAIA 1164
Query: 492 HRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWY-APEC----INY 546
HRD+ ++N+L+ I+D GL+ ++ N + + K Y APE +N
Sbjct: 1163 HRDIKSKNILVKKNGTCCIADLGLAVRYISESNEVDVAPNPRQGTKRYMAPEVLEMLLNV 984
Query: 547 YKFSS--KSDVWSFGVLMWE 564
F + ++D+++FG++MWE
Sbjct: 983 KNFDAFKQADMYAFGLVMWE 924
>26711
Length = 405
Score = 45.8 bits (107), Expect = 5e-05, Method: Composition-based stats.
Identities = 33/110 (30%), Positives = 52/110 (47%), Gaps = 3/110 (2%)
Frame = -2
Query: 474 LVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKIS--DFGLSKALRA-DENYYKAQT 530
+V QV ++++ VH DL N+LL + DFGL++ L E + T
Sbjct: 401 VVKQVLDILQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARKLYPPQETFLNHGT 222
Query: 531 HGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSE 580
G + +PE ++ S+ SDVW GVL + S GQ P++ +E
Sbjct: 221 PG-----FTSPEALDVKPISTASDVWGVGVLAYILLS-GQSPFQADSATE 90
>28157
Length = 400
Score = 45.4 bits (106), Expect = 8e-05, Method: Compositional matrix adjust.
Identities = 40/126 (31%), Positives = 61/126 (48%), Gaps = 8/126 (6%)
Frame = +3
Query: 397 KTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRMIGICEAESWMLVMEMAELGPL 456
K VAVK +++E K + E + ++ +P IV + G C LVME AE G L
Sbjct: 3 KDVAVKRIESEQE----KKSFMQELKQLSRVSHPNIVCLYGACRDHPVCLVMEYAEGGSL 170
Query: 457 NKYLQ----QNRHVKDKNIIELVHQVSMGMKYL---EESNFVHRDLAARNVLLV-TQHYA 508
L Q ++ + L+ Q ++G++YL + +HRDL N+LL+
Sbjct: 171 YNVLHGSGPQPQYTAAHAMNWLL-QCALGVEYLHGMKPKALIHRDLKPPNLLLIQCGTKL 347
Query: 509 KISDFG 514
KI DFG
Sbjct: 348 KICDFG 365
>04138
Length = 800
Score = 44.7 bits (104), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 24/86 (27%), Positives = 43/86 (50%), Gaps = 2/86 (2%)
Frame = +1
Query: 484 YLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPE- 542
Y+ + +HRD+ A N+L+ Q K++DFGL++A + T+ + WY P
Sbjct: 58 YIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTN-RVVTLWYRPPE 234
Query: 543 -CINYYKFSSKSDVWSFGVLMWEAFS 567
+ +S+ D W G +M E ++
Sbjct: 235 LLLGDRNYSTAIDQWGAGCIMAEMWT 312
>01392
Length = 1806
Score = 43.9 bits (102), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 30/130 (23%), Positives = 57/130 (43%), Gaps = 13/130 (10%)
Frame = -1
Query: 465 HVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHY-----AKISDFGLSKAL 519
H+ ++ +V ++ + +L HRDL N+L +H KI DF L+ +
Sbjct: 1803 HLCEREASLVVRHIARALDFLHSKGIAHRDLKPENIL--CEHLDDVVPVKICDFDLASGI 1630
Query: 520 RADENYYKAQTHGKWPV---KWYAPECI-----NYYKFSSKSDVWSFGVLMWEAFSYGQK 571
D + K PV ++ APE + + + + + D+WS G++++ G
Sbjct: 1629 SCDGDGTKTPELLT-PVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILYIMLC-GYP 1456
Query: 572 PYRGMKGSEV 581
P+ G G +
Sbjct: 1455 PFYGQCGEDC 1426
>11228
Length = 2155
Score = 43.1 bits (100), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 26/80 (32%), Positives = 41/80 (51%)
Frame = -2
Query: 5 GMADSANHLPFFFGNITREEAEDYLVQGGMSDGLYLLRQSRNYLGGFALSVAHGRKAHHY 64
G + LP+F +++EEA + L+ G +G +L+RQS NY G ++L + +
Sbjct: 1494 GDYEPVESLPYFHSCLSKEEAVEKLMLAG--EGSFLVRQSENYPGDYSLFFLCEKDVRRF 1321
Query: 65 TIERELNGTYAIAGGRTHAS 84
IER G + GGR S
Sbjct: 1320 RIERR--GNQFLVGGRLFDS 1267
>12786
Length = 460
Score = 42.4 bits (98), Expect = 6e-04, Method: Compositional matrix adjust.
Identities = 30/119 (25%), Positives = 51/119 (42%), Gaps = 20/119 (16%)
Frame = -3
Query: 481 GMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYA 540
+K L +H DL N +LV + K+ DFG++ L+ D+ + P + +
Sbjct: 374 AVKALHNEGVIHSDLKPANFMLVAGNL-KLIDFGIANTLQQDKTSVLKDSRVGTP-SYMS 201
Query: 541 PECINY--------------------YKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGS 579
PE I YK +SDVWS G +++ YG+ P++ +K +
Sbjct: 200 PEAIMAACDDSADDSMEEDGHRTKPKYKVGVRSDVWSLGCILYN-MVYGRTPFQHIKNN 27
>11185
Length = 473
Score = 42.0 bits (97), Expect = 7e-04, Method: Compositional matrix adjust.
Identities = 32/112 (28%), Positives = 51/112 (45%), Gaps = 19/112 (16%)
Frame = +1
Query: 475 VHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKA--LRADENYYK-AQTH 531
+H V+ G+ Y+ + DL VLL T K +DFGLSK +E ++K A+
Sbjct: 22 IHLVT-GLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAG 198
Query: 532 GKWPVK----------------WYAPECINYYKFSSKSDVWSFGVLMWEAFS 567
+W ++ + APE + S SD+W+ G + +E FS
Sbjct: 199 DQWNIQSAEEMMKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFS 354
>10546
Length = 790
Score = 40.8 bits (94), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 27/86 (31%), Positives = 44/86 (51%), Gaps = 6/86 (6%)
Frame = +2
Query: 165 KMPWFHGKISREESEQIVLIGSKTNGKFLIRARDNNGS--YALCLLHEGKVLHYRIDKDK 222
K W+HG I R + E +V K +G FL+R D + Y L + H+G V + RI
Sbjct: 317 KYEWYHGHIERSKGENLVKHVGK-DGTFLVRVSDKDPKFPYTLVVYHKGSVNNLRIRLRP 493
Query: 223 TGKLSIPEGKK----FDTLWQLVEHY 244
K+++ + KK F + ++EH+
Sbjct: 494 DDKVALGDEKKGEIAFQDVAAMIEHH 571
>30231
Length = 340
Score = 39.7 bits (91), Expect = 0.003, Method: Composition-based stats.
Identities = 30/78 (38%), Positives = 43/78 (55%), Gaps = 8/78 (10%)
Frame = -2
Query: 189 NGKFLIRARDN-NGSYALCLLHEGKVLHYRIDKDKTGKLSI-PEGK----KFDTLWQLVE 242
+G FL+R ++ + +Y LCLL + +V YRI DK G+LS+ EG F L L++
Sbjct: 252 DGSFLVRDSESVSNAYVLCLLFQLRVHQYRILPDKDGRLSVQSEGDMQPLSFIDLPSLIQ 73
Query: 243 HYSYKAD--GLLRVLTVP 258
Y K D GL+ L P
Sbjct: 72 VYISKGDKNGLICPLRRP 19
>13840
Length = 446
Score = 38.9 bits (89), Expect = 0.007, Method: Compositional matrix adjust.
Identities = 36/128 (28%), Positives = 67/128 (52%), Gaps = 8/128 (6%)
Frame = -1
Query: 376 ELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRM 435
E+G GN+GTV K +++ V +AVK +++ + K L+ VM+ + P+IV+
Sbjct: 374 EIGRGNYGTVNKMRHKITSTV--MAVKRIRSTVEEREQKQLLMDLDVVMRSNNCPFIVQF 201
Query: 436 IGIC--EAESWMLVMEMAELGPLNKYLQ----QNRHVKDKNIIELVHQVSM-GMKYL-EE 487
G E + W + ME+ E L+K+ + + + +NI+ + ++ + YL EE
Sbjct: 200 YGALFKEGDCW-ICMELME-TSLDKFYKFVYGEMQSSIPENILGKITVATLKALNYLKEE 27
Query: 488 SNFVHRDL 495
+HRD+
Sbjct: 26 LRIIHRDV 3
>21433
Length = 590
Score = 38.1 bits (87), Expect = 0.012, Method: Composition-based stats.
Identities = 28/98 (28%), Positives = 44/98 (44%)
Frame = +2
Query: 475 VHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKW 534
++Q+S ++Y +HRD+ N+LL + KI+DFG S + T
Sbjct: 185 IYQLSSALEYCHYRKVIHRDIKPENLLLGLKGDLKIADFGWSVHAPSSRRTTMCGT---- 352
Query: 535 PVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKP 572
+ + PE + D+WS GVL +E F G P
Sbjct: 353 -LDYLPPEMVEGKTHDENVDLWSLGVLCYE-FLVGTPP 460
>04627
Length = 572
Score = 37.7 bits (86), Expect = 0.014, Method: Compositional matrix adjust.
Identities = 21/56 (37%), Positives = 30/56 (53%), Gaps = 2/56 (3%)
Frame = +3
Query: 165 KMPWFHGKISREESEQIVLIGSKTNGKFLIRARDNNGS--YALCLLHEGKVLHYRI 218
K W+HG I R + E +V K +G FL+R D + Y L + H+G V + RI
Sbjct: 348 KYEWYHGHIERSKGENLVKHVGK-DGTFLVRVSDKDPKFPYTLVVYHKGSVNNLRI 512
>35671
Length = 567
Score = 37.7 bits (86), Expect = 0.015, Method: Compositional matrix adjust.
Identities = 17/45 (37%), Positives = 22/45 (48%)
Frame = -3
Query: 586 EKGERMGCPAGCPREMYDLMNLCWTYDVENRPGFAAVELRLRNYY 630
+KG R+ P C E Y +M CWT E RP F + + N Y
Sbjct: 565 QKGNRLAKPISCTDEAYKVMLQCWTESREERPTFKKLVPVMENLY 431
>00394
Length = 548
Score = 37.0 bits (84), Expect = 0.024, Method: Compositional matrix adjust.
Identities = 32/103 (31%), Positives = 50/103 (48%), Gaps = 6/103 (5%)
Frame = -2
Query: 366 DRKLLTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQ 425
D + L DKE+G G+F TV KG V VA L+++ + A + EA +++
Sbjct: 304 DNRFLKF-DKEIGRGSFKTVYKGLDTELGV--AVAWCELQDKKWNKAERQRFKEEAEMLK 134
Query: 426 QLDNPYIVRMIGICEAES------WMLVMEMAELGPLNKYLQQ 462
+L +P IVR E + +LV E+ G L YL++
Sbjct: 133 ELQHPNIVRFFDYWEEHNHRNRKVIILVTELMTSGTLKTYLKR 5
>18881
Length = 762
Score = 36.2 bits (82), Expect = 0.040, Method: Compositional matrix adjust.
Identities = 19/58 (32%), Positives = 32/58 (55%), Gaps = 2/58 (3%)
Frame = -3
Query: 189 NGKFLIRARDNNGSYALCLLH--EGKVLHYRIDKDKTGKLSIPEGKKFDTLWQLVEHY 244
+G FLIR N + C + V H +++++ G+ + +G FD++ QLVEHY
Sbjct: 745 DGTFLIRVT-NTSARESCPQY*YANAVRHIKVNRNPQGRFYLADGHYFDSVQQLVEHY 575
>18481
Length = 437
Score = 35.8 bits (81), Expect = 0.047, Method: Composition-based stats.
Identities = 44/129 (34%), Positives = 65/129 (50%), Gaps = 8/129 (6%)
Frame = -1
Query: 397 KTVAVKILKNEANDPALKDELLA-EANVMQQLD-NPYIVRMIGI-CEAESWMLVMEMAEL 453
K +AVKI EA D +K +LL EA V +Q+ +P + M E LVME+ L
Sbjct: 407 KDIAVKI---EAID--VKHQLLHYEAKVYEQIGRHPGLPTMYHYGTEKHFNALVMEL--L 249
Query: 454 GPLNK--YLQQNRHVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQ---HYA 508
GP + ++ R K I+ + Q+ ++++ + F+HRDL N L+ H
Sbjct: 248 GPSLEELFVICKRRFTLKTILMVSDQLLSRLEFIHQKCFIHRDLKPDNFLMGLGRHCHRL 69
Query: 509 KISDFGLSK 517
I DFGLSK
Sbjct: 68 YIIDFGLSK 42
>31489
Length = 329
Score = 35.4 bits (80), Expect = 0.064, Method: Composition-based stats.
Identities = 14/46 (30%), Positives = 30/46 (65%)
Frame = +3
Query: 456 LNKYLQQNRHVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVL 501
L++ + ++ + +++I ++Q+ G+KY+ +N VHRDL N+L
Sbjct: 126 LHRIIYSDQPLTEEHIRYFLYQILRGLKYIHSANVVHRDLKPSNLL 263
>31789
Length = 676
Score = 35.0 bits (79), Expect = 0.10, Method: Compositional matrix adjust.
Identities = 40/151 (26%), Positives = 68/151 (45%), Gaps = 9/151 (5%)
Frame = +2
Query: 341 LPMDTEVYESPYADP-EEIRPKEVYL--DRKLLTLEDKELGSGNFGTVKKGYYQMKKVVK 397
L ++ E+ + A +EI K V D + L D E+G G+F TV KG V
Sbjct: 230 LQLEGEIKDIQQAQKVQEIEEKAVASSPDNRFLKF-DVEIGRGSFKTVYKGLDTELGVA- 403
Query: 398 TVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRMIGICEAES------WMLVMEMA 451
VA L+++ + + EA ++++L +P IVR E + +LV E+
Sbjct: 404 -VAWCELQDKKWNKTERQRFKEEAEMLKELQHPNIVRFFDYWEEHNHRNRKVIILVTELM 580
Query: 452 ELGPLNKYLQQNRHVKDKNIIELVHQVSMGM 482
G L YL++ + + K + Q+ G+
Sbjct: 581 TSGTLKTYLKRFKKINLKVLKNWCRQILKGL 673
>14257
Length = 919
Score = 33.9 bits (76), Expect = 0.20, Method: Compositional matrix adjust.
Identities = 23/83 (27%), Positives = 43/83 (51%), Gaps = 2/83 (2%)
Frame = -3
Query: 168 WFHGKISREESEQIVLIGSKTNGKFLIRARDNNGS-YALCLLHEGKVLH-YRIDKDKTGK 225
W+HGKI R+E+E+++ + +G FL+R N+ + + L G V H +D D +
Sbjct: 890 WYHGKIGRKEAEKLL----ELDGDFLVREASNSAAQFVLSGRQNGNVRHLLLVDPDGIVR 723
Query: 226 LSIPEGKKFDTLWQLVEHYSYKA 248
+ FD++ L+ ++ A
Sbjct: 722 ---TKDFIFDSVSHLINYHRQNA 663
>26009
Length = 886
Score = 33.9 bits (76), Expect = 0.23, Method: Compositional matrix adjust.
Identities = 11/51 (21%), Positives = 28/51 (54%)
Frame = +3
Query: 461 QQNRHVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKIS 511
++N+ + ++ Q+ + ++ VHRD+ NVL++T ++++S
Sbjct: 687 RRNKACGSREAKSVMKQLVSALDFMHSKQLVHRDIKPENVLILTPDFSRVS 839
>16708
Length = 1397
Score = 33.1 bits (74), Expect = 0.32, Method: Compositional matrix adjust.
Identities = 27/118 (22%), Positives = 52/118 (44%), Gaps = 11/118 (9%)
Frame = -1
Query: 446 LVMEMAELGPL-NKYLQQNRHVKDKN----------IIELVHQVSMGMKYLEESNFVHRD 494
+++ E+GPL N Y H K+K + + Q ++++ E VH D
Sbjct: 1184 ILLHFYEMGPLCNVY----AHYKNKEMPIRWSNPAMVCCIAGQXVCALEHIHELGVVHMD 1017
Query: 495 LAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINYYKFSSK 552
+ A NVL+ K++D+G+++ + Y A P + ++ C N F ++
Sbjct: 1016 VKADNVLVDAHGNCKLTDYGIAQLYKV----YPA------PTETHSSGCTNKRTFYTR 873
>38046
Length = 446
Score = 33.1 bits (74), Expect = 0.38, Method: Composition-based stats.
Identities = 11/25 (44%), Positives = 19/25 (76%)
Frame = -1
Query: 478 VSMGMKYLEESNFVHRDLAARNVLL 502
++ M Y+E+ NF+HR+L RN+L+
Sbjct: 98 IADAMAYMEKENFIHRNLGDRNILV 24
>21210
Length = 518
Score = 32.3 bits (72), Expect = 0.53, Method: Compositional matrix adjust.
Identities = 25/91 (27%), Positives = 42/91 (46%), Gaps = 9/91 (9%)
Frame = +3
Query: 538 WYAPECIN----YYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGC 593
+ APE I+ + + +SDVWS G+ + E + G+ PYR K + L++ R
Sbjct: 18 YMAPERIDPRASSHGYDVRSDVWSLGITLME-LATGRFPYR--KWVSIFDQLQQVVRGVA 188
Query: 594 PA-----GCPREMYDLMNLCWTYDVENRPGF 619
P + + +N C T D + RP +
Sbjct: 189 PCLPHDGAFSHDFVNFVNKCLTKDEKQRPKY 281
>36481
Length = 806
Score = 32.3 bits (72), Expect = 0.54, Method: Compositional matrix adjust.
Identities = 38/152 (25%), Positives = 67/152 (44%), Gaps = 19/152 (12%)
Frame = +2
Query: 378 GSGNFGTVKKGYYQMKKVVK--TVAVKILKNEANDPALKDELLAEANVMQQL--DNPY-- 431
G G FG V Q K ++K +A+KI+KN ++ E NV+++L +P+
Sbjct: 389 GEGTFGKV----VQCKDLLKGDDIALKIIKNV---DKYREAAKLEINVLEKLREKDPHAK 547
Query: 432 --IVRMIG-------ICEAESWMLVMEMAELGPLNKY----LQQNRHVKDKNIIELVHQV 478
V+M+ +C + ML + + + N Y ++Q RH+ +Q+
Sbjct: 548 HMCVQMLDWFDYHGHVCISFH-MLGLSVFDFLKDNSYGAYPIEQVRHIS--------YQL 700
Query: 479 SMGMKYLEESNFVHRDLAARNVLLVTQHYAKI 510
+ +L E+ H DL N+L V Y +
Sbjct: 701 CYAVNFLHENQLTHTDLKPENILFVDSQYENV 796
>15741
Length = 402
Score = 32.3 bits (72), Expect = 0.58, Method: Composition-based stats.
Identities = 13/33 (39%), Positives = 20/33 (60%)
Frame = -3
Query: 469 KNIIELVHQVSMGMKYLEESNFVHRDLAARNVL 501
++ V+ GM ++ + VHRD+AARNVL
Sbjct: 100 RDFFSFALHVARGMAHVANNKIVHRDVAARNVL 2
>18401
Length = 463
Score = 32.0 bits (71), Expect = 0.75, Method: Compositional matrix adjust.
Identities = 17/48 (35%), Positives = 26/48 (54%)
Frame = -3
Query: 540 APECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEK 587
APE I +S DVWS G +M+E ++ G ++ E AM+E+
Sbjct: 428 APEVILELGWSHPCDVWSVGCIMFELYT-GYTLFQTHDNKEHLAMMER 288
>00191
Length = 1400
Score = 31.6 bits (70), Expect = 1.1, Method: Compositional matrix adjust.
Identities = 16/39 (41%), Positives = 21/39 (53%)
Frame = -1
Query: 369 LLTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKNE 407
L L D LG NF K G+ +KKV+KT+ KN+
Sbjct: 1130 LXCLADPCLGVRNFRDTKSGFPPLKKVMKTITKPYXKNK 1014
>29590
Length = 320
Score = 31.2 bits (69), Expect = 1.4, Method: Composition-based stats.
Identities = 14/46 (30%), Positives = 26/46 (56%)
Frame = +3
Query: 538 WYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTA 583
+ APE ++Y S ++D+WS GVL + + P+ G+ + +A
Sbjct: 72 YVAPEVLDYEPLSIQTDMWSLGVLSYVMLT-ACSPFVGITSKKHSA 206
>25019
Length = 730
Score = 30.8 bits (68), Expect = 1.8, Method: Compositional matrix adjust.
Identities = 20/68 (29%), Positives = 28/68 (41%), Gaps = 4/68 (5%)
Frame = +3
Query: 496 AARNVLLVTQHYAKISDFGLSK----ALRADENYYKAQTHGKWPVKWYAPECINYYKFSS 551
AA NVLL + K++DFGL K R + +++ APE +
Sbjct: 255 AAENVLLDKDGHVKLTDFGLCKEAITGTRVTHTFCGT-------IEYMAPEILTRTGHGK 413
Query: 552 KSDVWSFG 559
D WS G
Sbjct: 414 AVDWWSLG 437
>02638
Length = 1490
Score = 30.4 bits (67), Expect = 2.1, Method: Compositional matrix adjust.
Identities = 26/97 (26%), Positives = 39/97 (40%), Gaps = 4/97 (4%)
Frame = +1
Query: 526 YKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAML 585
++ Q G + + APE + + DVWS G +M E + + P+ S A++
Sbjct: 4 FQGQLLGT--IAFMAPEVLRGESYGRACDVWSVGCVMIEMCTC-RPPWNSHDISNHLALI 174
Query: 586 EKGERMGCPAGCPREMY----DLMNLCWTYDVENRPG 618
K P P M DLM C D + RP
Sbjct: 175 FKIASSVDPPPIPENMSPPVRDLMLRCLEQDSDFRPS 285
>37602
Length = 804
Score = 30.0 bits (66), Expect = 2.7, Method: Compositional matrix adjust.
Identities = 17/72 (23%), Positives = 30/72 (41%)
Frame = -1
Query: 442 ESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVL 501
E + ME G + + + I + + G+ YL +HRD+ N+L
Sbjct: 300 EKLWIAMEYCGGGSMQDIYHVTGPLTEPQIAFVCRETLKGLHYLHRRGKMHRDIKGANIL 121
Query: 502 LVTQHYAKISDF 513
L + K++DF
Sbjct: 120 LTEEGDVKLADF 85
>07933
Length = 728
Score = 29.6 bits (65), Expect = 4.0, Method: Compositional matrix adjust.
Identities = 11/30 (36%), Positives = 17/30 (56%)
Frame = +3
Query: 594 PAGCPREMYDLMNLCWTYDVENRPGFAAVE 623
P CP +Y++M CW+ + RP F +E
Sbjct: 3 PNYCPNLLYNIMMQCWSAEPSARPTFHKLE 92
>14799
Length = 565
Score = 29.6 bits (65), Expect = 4.4, Method: Composition-based stats.
Identities = 17/43 (39%), Positives = 21/43 (48%)
Frame = -3
Query: 369 LLTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDP 411
L L D LG NF K G+ +KKV+KT+ K N P
Sbjct: 302 LRCLADPCLGVRNFRDTKSGFPPLKKVMKTITKPYNKKXKNRP 174
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000364907 | hsapiens_gene_ensembl |
Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase).
[Source:Uniprot/SWISSPROT;Acc:P43405]
(635 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
06405 196 2e-50
21808 194 1e-49
14477 182 3e-46
09007 173 2e-43
11780 100 7e-41
04852 139 4e-33
07291 129 4e-30
14116 129 4e-30
20640 125 5e-29
17300 115 9e-27
07940 117 2e-26
22005 93 1e-24
18996 103 2e-22
08294 98 1e-20
17637 84 2e-16
18921 82 8e-16
01707 80 3e-15
13305 79 8e-15
00715 78 8e-15
17253 77 3e-14
01718 75 8e-14
13066 69 9e-12
19301 67 2e-11
01756 66 3e-11
12721 66 4e-11
14420 65 7e-11
09606 65 1e-10
21079 63 3e-10
18484 62 1e-09
00300 61 1e-09
01060 60 2e-09
14126 60 2e-09
13212 60 3e-09
31885 59 9e-09
19094 57 3e-08
04591 56 4e-08
29581 55 7e-08
12672 54 1e-07
17806 54 2e-07
27546 50 2e-06
25550 49 2e-06
19761 50 4e-06
07833 50 4e-06
26560 49 6e-06
30755 49 6e-06
27405 47 2e-05
01966 47 3e-05
03240 47 3e-05
15910 46 5e-05
07836 46 5e-05
26711 46 5e-05
28157 45 8e-05
04138 45 1e-04
01392 44 2e-04
11228 43 4e-04
12786 42 6e-04
11185 42 7e-04
10546 41 0.002
30231 40 0.003
13840 39 0.007
21433 38 0.012
04627 38 0.014
35671 38 0.015
00394 37 0.024
18881 36 0.040
18481 36 0.047
31489 35 0.064
31789 35 0.10
14257 34 0.20
26009 34 0.23
16708 33 0.32
38046 33 0.38
21210 32 0.53
36481 32 0.54
15741 32 0.58
18401 32 0.75
00191 32 1.1
29590 31 1.4
25019 31 1.8
02638 30 2.1
37602 30 2.7
07933 30 4.0
14799 30 4.4
>06405
Length = 1965
Score = 196 bits (498), Expect = 2e-50, Method: Compositional matrix adjust.
Identities = 107/286 (37%), Positives = 169/286 (59%), Gaps = 5/286 (1%)
Frame = +1
Query: 350 SPYADPEEIRPKEVYLDRKLLTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEAN 409
SP D EI E+ + +L G G +G V + + K+ K VAVK LK +
Sbjct: 226 SPEPDRWEIERTEIAMKHRL--------GGGQYGDVYEAMW--KRYNKIVAVKTLKEDTM 375
Query: 410 DPALKDELLAEANVMQQLDNPYIVRMIGICEAES-WMLVMEMAELGPLNKYLQQNRHVKD 468
AL D L EA +M+++ +P +V+++G+C E + +V E G L YL+ + ++
Sbjct: 376 --ALND-FLEEAAIMKEMKHPNLVQLLGVCTREPPFYIVTEFMPHGNLLDYLRSS--TRE 540
Query: 469 KN----IIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADEN 524
+N ++ + Q++ GM YLE NF+HRDLAARN L+ + K++DFGL++ ++ D
Sbjct: 541 ENGPTALMYMATQIASGMAYLETKNFIHRDLAARNCLVADSNMVKVADFGLARLMKDDT- 717
Query: 525 YYKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAM 584
Y A K+P+KW APE + + +FS++SD+W+FGVL+WE +YG PY G++ +EV +
Sbjct: 718 -YTAHIGAKFPIKWTAPEGLAFNRFSTRSDIWAFGVLLWELATYGMSPYPGVELTEVYHL 894
Query: 585 LEKGERMGCPAGCPREMYDLMNLCWTYDVENRPGFAAVELRLRNYY 630
LE+G RM P G P ++Y LM CW +D ++RP F + L N +
Sbjct: 895 LERGYRMERPPGTPADVYILMLKCWQWDPKDRPTFKEIHFLLENMF 1032
Score = 52.4 bits (124), Expect = 5e-07, Method: Compositional matrix adjust.
Identities = 29/75 (38%), Positives = 43/75 (57%)
Frame = +1
Query: 201 GSYALCLLHEGKVLHYRIDKDKTGKLSIPEGKKFDTLWQLVEHYSYKADGLLRVLTVPCQ 260
G ++ + EG+V HYRI +D GK+ + + +F+TL +LV H+S ADGL+ L P
Sbjct: 19 GQRSISVRFEGRVYHYRITEDD-GKVFVTQEHRFNTLAELVHHHSIHADGLVTTLLYPAP 195
Query: 261 KIGTQGNVNFGGRPQ 275
K Q FG P+
Sbjct: 196 K--RQKPTVFGVSPE 234
Score = 32.0 bits (71), Expect = 0.87, Method: Compositional matrix adjust.
Identities = 25/84 (29%), Positives = 40/84 (47%), Gaps = 5/84 (5%)
Frame = +1
Query: 43 QSRNYLGGFALSVAHGRKAHHYTIERELNGTYAIAGGRTHASPADLCHYHSQESDGLVCL 102
+S + G ++SV + +HY I E +G + + A+L H+HS +DGLV
Sbjct: 1 ESESSPGQRSISVRFEGRVYHYRIT-EDDGKVFVTQEHRFNTLAELVHHHSIHADGLVTT 177
Query: 103 LKKPFNRPQ-----GVQPKTGPFE 121
L P + Q GV P+ +E
Sbjct: 178 LLYPAPKRQKPTVFGVSPEPDRWE 249
>21808
Length = 1011
Score = 194 bits (492), Expect = 1e-49, Method: Compositional matrix adjust.
Identities = 92/221 (41%), Positives = 146/221 (66%), Gaps = 2/221 (0%)
Frame = +1
Query: 399 VAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRMIGIC-EAESWMLVMEMAELGPLN 457
VA+K LK+ DP + LAEA +M++L +P ++++ +C + + ++ E+ + G L
Sbjct: 28 VAIKTLKSGTMDP---KDFLAEAQIMKKLRHPKLIQLYAVCTQDDPIFIITELMKNGSLL 198
Query: 458 KYLQ-QNRHVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLS 516
++LQ + R +K +I++ Q++ GM YLE N++HRDLAARN+L+ + KI+DFGL+
Sbjct: 199 EFLQGKGRVLKLPALIDIGAQIACGMAYLESQNYIHRDLAARNILVSDNNTVKIADFGLA 378
Query: 517 KALRADENYYKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGM 576
+ ++ DE Y+A+ ++P+KW APE NY +F+ KSDVWSFG+L+ E +YG+ PY GM
Sbjct: 379 RVIKEDE--YEARVGARFPIKWTAPEAANYNRFTIKSDVWSFGILLTETVTYGRVPYPGM 552
Query: 577 KGSEVTAMLEKGERMGCPAGCPREMYDLMNLCWTYDVENRP 617
+EV +E G RM CP GCP+ +YD+M CW + RP
Sbjct: 553 TNAEVLHQVEHGYRMPCPPGCPKPLYDIMLECWRKEEMERP 675
>14477
Length = 493
Score = 182 bits (463), Expect = 3e-46, Method: Compositional matrix adjust.
Identities = 86/160 (53%), Positives = 125/160 (78%)
Frame = -1
Query: 370 LTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQLDN 429
+ +++ +LG+GNFG+V KG ++ VA+K+LKN DP+++ EL+ EA VM+++D+
Sbjct: 487 IQMDELKLGAGNFGSVMKGVCRLDDREIPVAIKVLKNADLDPSVQSELIKEAEVMKKMDH 308
Query: 430 PYIVRMIGICEAESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSMGMKYLEESN 489
+IVR+IG+CE E+ MLV+E+A+LGPLNK+L +N+H+ NI+EL+ QVS GM+YLE +
Sbjct: 307 MHIVRLIGLCEGETMMLVLELAKLGPLNKFLPKNKHLPLWNILELMWQVSQGMEYLEANK 128
Query: 490 FVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQ 529
FVHRDLAARN+LL +H+AKISDFG+SK L + NYY AQ
Sbjct: 127 FVHRDLAARNILLCDEHFAKISDFGMSKTLSRENNYYMAQ 8
>09007
Length = 1440
Score = 173 bits (438), Expect = 2e-43, Method: Compositional matrix adjust.
Identities = 102/265 (38%), Positives = 150/265 (56%), Gaps = 13/265 (4%)
Frame = -1
Query: 375 KELGSGNFGTVKKGYYQMKKVVKT-VAVKILKNEANDPALKD--ELLAEANVMQQLDNPY 431
K LG G+FGTV++ + + K VAVK L + D KD E L E +MQ LD+
Sbjct: 861 KSLGQGHFGTVRQAIWTAESGEKVQVAVKCL---SKDKIHKDGQEFLKETAIMQMLDHEN 691
Query: 432 IVRMIGICEAESWMLVMEMAELGPLNKYLQQNRHVKDK------NIIELVHQVSMGMKYL 485
IVR+ G+ ++ +M + EL P+ L+ + V + + + QV GM YL
Sbjct: 690 IVRVYGVV-MDNGADIMLVTELAPMRSLLECVKEVSARVDFSVPRLCDFSQQVCDGMSYL 514
Query: 486 EESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQ--THGKWPVKWYAPEC 543
E VHRDLAARN+LL ++ KISD G+S AL A + YY++Q H + V W APE
Sbjct: 513 ESKRLVHRDLAARNILLFSKSKVKISDVGVSGALGAGKEYYQSQQTIHLQNAVAWCAPES 334
Query: 544 INYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLE--KGERMGCPAGCPREM 601
FSS SDVW+FGVL+WE F++G +P+ G+ G ++ ++ + +R+ P CP+E
Sbjct: 333 FRNLCFSSASDVWAFGVLLWEFFTHGFQPWAGLNGQQIMEAVDAPQSQRLEQPDLCPKEY 154
Query: 602 YDLMNLCWTYDVENRPGFAAVELRL 626
Y +M CW + + RP F+ + L L
Sbjct: 153 YAVMLKCWEQEPQRRPTFSQLFLTL 79
>11780
Length = 1713
Score = 99.8 bits (247), Expect(2) = 7e-41, Method: Compositional matrix adjust.
Identities = 65/170 (38%), Positives = 91/170 (53%), Gaps = 2/170 (1%)
Frame = +3
Query: 377 LGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRMI 436
+G G+FG V KG Y+ + VA+K LK++ + L EA+VM L + +VR+I
Sbjct: 621 IGKGDFGDVYKGMYRGQ----PVAIKQLKDKDRG---EQSFLQEASVMTSLRHDNLVRLI 779
Query: 437 GICEAESWMLVMEMAELGPLNKYLQQNRH--VKDKNIIELVHQVSMGMKYLEESNFVHRD 494
G+ E+ LV E G L +YL+ + K+ I M+YLE VHRD
Sbjct: 780 GVVLGETIFLVTEFMGKGNLVEYLRSRGRSVITKKDQINFATDTCAAMEYLESKRLVHRD 959
Query: 495 LAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECI 544
LAARNVL+ AK+SDFGL+K +QT K+P+KW APE +
Sbjct: 960 LAARNVLVHDDGKAKVSDFGLAKFGDF------SQTSVKFPIKWTAPEAL 1091
Score = 86.7 bits (213), Expect(2) = 7e-41, Method: Compositional matrix adjust.
Identities = 38/81 (46%), Positives = 53/81 (65%)
Frame = +1
Query: 548 KFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAGCPREMYDLMNL 607
KF+SKSD+WSFG+L+WE +S+G+ PY + ++V +E+G RM P GCP E+Y +M
Sbjct: 1102 KFTSKSDMWSFGILLWEIYSFGRVPYPRIPLTDVVMHVERGYRMEAPEGCPPEIYSIMKQ 1281
Query: 608 CWTYDVENRPGFAAVELRLRN 628
W D RP F +V RL N
Sbjct: 1282 AWELDPNERPTFKSVLARLNN 1344
Score = 81.6 bits (200), Expect = 8e-16, Method: Compositional matrix adjust.
Identities = 50/107 (46%), Positives = 64/107 (59%), Gaps = 1/107 (0%)
Frame = +3
Query: 166 MPWFHGKISREESEQIVLIGSKTNGKFLIRARDNN-GSYALCLLHEGKVLHYRIDKDKTG 224
MPWFHGKI+R+++E+ L+ + +G FLIR N G Y LC+ H GKV HYRI +
Sbjct: 249 MPWFHGKITRQQAEE--LLKPREDGLFLIRESSNYPGDYTLCVCHLGKVEHYRILY-REN 419
Query: 225 KLSIPEGKKFDTLWQLVEHYSYKADGLLRVLTVPCQKIGTQGNVNFG 271
+L+I E F L +LV+HY ADGL LT P K G NFG
Sbjct: 420 QLTIDEEGFFRNLDELVKHYLADADGLCTQLTRPVTKQGG----NFG 548
Score = 53.5 bits (127), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 43/133 (32%), Positives = 65/133 (48%), Gaps = 1/133 (0%)
Frame = +3
Query: 13 LPFFFGNITREEAEDYLVQGGMSDGLYLLRQSRNYLGGFALSVAHGRKAHHYTI-ERELN 71
+P+F G ITR++AE+ L DGL+L+R+S NY G + L V H K HY I RE
Sbjct: 249 MPWFHGKITRQQAEELLKP--REDGLFLIRESSNYPGDYTLCVCHLGKVEHYRILYRENQ 422
Query: 72 GTYAIAGGRTHASPADLCHYHSQESDGLVCLLKKPFNRPQGVQPKTGPFEDLKENLIREY 131
T G + +L ++ ++DGL L +P V + G F + ++E+
Sbjct: 423 LTIDEEG--FFRNLDELVKHYLADADGLCTQLTRP------VTKQGGNFGTVS---LQEF 569
Query: 132 VKQTWNLQGQALE 144
W + Q LE
Sbjct: 570 KSGGWVIAXQDLE 608
>04852
Length = 1462
Score = 139 bits (350), Expect = 4e-33, Method: Compositional matrix adjust.
Identities = 85/255 (33%), Positives = 132/255 (51%), Gaps = 32/255 (12%)
Frame = +1
Query: 398 TVAVKILKNEANDPALKDELLAEANVMQQL----DNPYIVRMIGICE--AESWMLVMEMA 451
TVAVK+L++ +D + E VM+ + + IV +G C W++V E A
Sbjct: 25 TVAVKMLRDIVTAVEEQD-FVQELQVMKAVKKMGSHINIVNFLGCCTQGGPLWVIV-EFA 198
Query: 452 ELGPLNKYLQQNRH-------------------------VKDKNIIELVHQVSMGMKYLE 486
+ G L +L+ R ++ KN++ Q++ GM++L
Sbjct: 199 KNGNLRDFLESCRDGINGYGKFVSPQDPGWYTKTPGGHVIRRKNLLSYAFQIARGMEFLA 378
Query: 487 ESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINY 546
+HRDLAARNVL+ +H KI+DFGLS+ +YYK ++ G+ PVKW APE +
Sbjct: 379 SRKCIHRDLAARNVLVTEEHVLKIADFGLSRT----GDYYKKRSGGRLPVKWMAPEALFD 546
Query: 547 YKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEV-TAMLEKGERMGCPAGCPREMYDLM 605
++++KSDVWSFGV++WE FS G PY + E+ + +L+ RM P +Y +M
Sbjct: 547 MRYTTKSDVWSFGVVLWEIFSLGGMPYASIPNEELYSKLLDDAYRMPRPELASGNLYAIM 726
Query: 606 NLCWTYDVENRPGFA 620
CW +RP F+
Sbjct: 727 ERCWLNRPSDRPEFS 771
>07291
Length = 833
Score = 129 bits (324), Expect = 4e-30, Method: Compositional matrix adjust.
Identities = 59/159 (37%), Positives = 94/159 (59%)
Frame = +1
Query: 471 IIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQT 530
+++ Q++ GM YL+E VHR+LAARN ++ ++SD+G++ +L Y +
Sbjct: 55 LLDFGRQIADGMAYLQEVKVVHRNLAARNCIVTEDGRLQLSDYGVTGSLFPQSYYTADDS 234
Query: 531 HGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGER 590
+ VKW APE I+ + FSSKSDVW+FGV++WE + G PY ++ S + L++G R
Sbjct: 235 PARDLVKWMAPETIDNFHFSSKSDVWAFGVVLWELLTRGITPYPDVENSSLLPYLKEGHR 414
Query: 591 MGCPAGCPREMYDLMNLCWTYDVENRPGFAAVELRLRNY 629
M P P +Y++M CW E RP FA + +L+ +
Sbjct: 415 MKKPKQSPEPVYEMMTACWNESPEQRPDFAELNDQLKTF 531
>14116
Length = 1017
Score = 129 bits (323), Expect = 4e-30, Method: Compositional matrix adjust.
Identities = 77/217 (35%), Positives = 119/217 (54%), Gaps = 5/217 (2%)
Frame = -1
Query: 358 IRPKEVYLDRKLLTLEDKELGSGNFGTVKKGYYQM--KKVVKTVAVKILKNEANDPALKD 415
I + + +DR+ LT+ +E+G GNFG VK+G+ + +K VAVK L N
Sbjct: 666 IENESLLIDREFLTM-GEEIGKGNFGCVKRGFLTLPEQKGDILVAVKTLHNNNPREIELQ 490
Query: 416 ELLAEANVMQQLDNPYIVRMIGICEAESWM--LVMEMAELGPLNKYLQQNRHVKD-KNII 472
L EA +M+ + ++ +IGIC M +V+ + G L Y++ ++H K++I
Sbjct: 489 SFLQEALIMKDFHHSNVLTLIGICLNLDDMPLVVLPFMKHGDLLTYIRDDQHQPTIKDLI 310
Query: 473 ELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHG 532
++ GM YL FVHRDLAARN +L + K++DFGL++ + E Y
Sbjct: 309 MYGVDIARGMDYLAGLKFVHRDLAARNCMLDEDFHVKVADFGLARDIYEKEYYSSENKKA 130
Query: 533 KWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYG 569
K PVKW A E + + SK+DVWS+GV++WE + G
Sbjct: 129 KLPVKWMALESLEKGNYDSKTDVWSYGVVLWELLTRG 19
>20640
Length = 1492
Score = 125 bits (314), Expect = 5e-29, Method: Compositional matrix adjust.
Identities = 58/139 (41%), Positives = 84/139 (60%)
Frame = +1
Query: 490 FVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINYYKF 549
+VHRDLA RN L+ KISDFGL++++ + +YY+ H P++W E I Y KF
Sbjct: 7 YVHRDLATRNCLVGHDLVVKISDFGLARSVHS-VDYYRGSEHDAIPIRWMPLEAILYNKF 183
Query: 550 SSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAGCPREMYDLMNLCW 609
S++SDVWSFGV++WE F++ +PY G+ EV +++G+ + CP P MY+LM CW
Sbjct: 184 STQSDVWSFGVVLWEIFAFALQPYYGLTHEEVVRFVKEGKVLACPERTPPPMYELMKQCW 363
Query: 610 TYDVENRPGFAAVELRLRN 628
RP F + L N
Sbjct: 364 HRRPATRPSFHTLHKTLEN 420
>17300
Length = 480
Score = 115 bits (287), Expect(2) = 9e-27, Method: Compositional matrix adjust.
Identities = 57/116 (49%), Positives = 76/116 (65%), Gaps = 2/116 (1%)
Frame = +1
Query: 478 VSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRAD--ENYYKAQTHGKWP 535
+S GM L + +VHRDLAARN+L+ K++DFGLS+ + +D E Y + GK P
Sbjct: 1 ISSGMGXLADMGYVHRDLAARNILVNEILVCKVADFGLSREIESDTTEGAYTTK-GGKIP 177
Query: 536 VKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERM 591
V+W APE I Y KF+S SDVWSFGV+MWE SYG++PY +V +EKG R+
Sbjct: 178 VRWTAPEAIAYRKFTSASDVWSFGVVMWEVMSYGERPYWNWSNQDVIKAVEKGYRL 345
Score = 23.9 bits (50), Expect(2) = 9e-27, Method: Composition-based stats.
Identities = 10/32 (31%), Positives = 16/32 (50%), Gaps = 1/32 (3%)
Frame = +2
Query: 592 GCPA-GCPREMYDLMNLCWTYDVENRPGFAAV 622
CP+ CP ++ LM W + +RP + V
Sbjct: 341 ACPSMDCPEALHQLMLDAWQKERSHRPKMSMV 436
>07940
Length = 1336
Score = 117 bits (292), Expect = 2e-26, Method: Compositional matrix adjust.
Identities = 53/105 (50%), Positives = 75/105 (71%)
Frame = -3
Query: 469 KNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKA 528
K++I +QV+ GM+YL +HRDLAARNVL+ ++ KI+DFGL++ L+ +YY+
Sbjct: 347 KDLISYAYQVARGMEYLASKQCIHRDLAARNVLVAEEYVLKIADFGLTRNLQ-QFDYYRK 171
Query: 529 QTHGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPY 573
T G+ PVKW APE + K++SKSDVWS+GVL+WE F+ G PY
Sbjct: 170 TTDGRLPVKWMAPEALFDRKYTSKSDVWSYGVLLWEIFTLGGNPY 36
>22005
Length = 873
Score = 93.2 bits (230), Expect(2) = 1e-24, Method: Compositional matrix adjust.
Identities = 74/244 (30%), Positives = 118/244 (48%), Gaps = 54/244 (22%)
Frame = +1
Query: 375 KELGSGNFGTVKK-GYYQMKKVVKTVAV--------KILKNEANDPALKDELLAEANVMQ 425
+++G G FG V K + + +V + K+LK +A++ L+ + EA++M
Sbjct: 1 RDIGQGAFGRVSKLKFLGLASLVGELIPEKRP*LL*KMLKEDASED-LQSDFEREASLMA 177
Query: 426 QLDNPYIVRMIGICEAESWM-LVMEMAELGPLNKYLQ--------------QNRHV---- 466
D+P IV+++G+C M L+ E G LN +L+ QN V
Sbjct: 178 DFDHPNIVKLLGVCAIGKPMCLLFEFMSKGDLNDFLRLCSPENYNLPVSRSQNLVVDLED 357
Query: 467 ------------KD--------------KNIIELVHQVSMGMKYLEESNFVHRDLAARNV 500
KD K+ + + Q+S GM YL + ++VHRDLA R V
Sbjct: 358 GLRVEVEAEECEKDTQSEDRDCSGMLXTKDQLYISQQISAGMAYLAQKDYVHRDLATRTV 537
Query: 501 LLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFGV 560
+ ISDFGL++++ + +YY+ P++W E I Y KFS++SDVWSFGV
Sbjct: 538 X-SRTT*S*ISDFGLARSVHS-VDYYRGSEQDAIPIRWMPLEAILYSKFSTQSDVWSFGV 711
Query: 561 LMWE 564
++WE
Sbjct: 712 VLWE 723
Score = 38.5 bits (88), Expect(2) = 1e-24, Method: Compositional matrix adjust.
Identities = 16/53 (30%), Positives = 28/53 (52%)
Frame = +3
Query: 566 FSYGQKPYRGMKGSEVTAMLEKGERMGCPAGCPREMYDLMNLCWTYDVENRPG 618
F++ +PY G+ EV ++ G+ + P P ++Y+LM CW + RP
Sbjct: 726 FAFALQPYYGLTHEEVVNYVKAGKILEQPTKTPHQVYELMKQCW----QRRPA 872
>18996
Length = 491
Score = 103 bits (257), Expect = 2e-22, Method: Compositional matrix adjust.
Identities = 60/137 (43%), Positives = 79/137 (57%), Gaps = 5/137 (3%)
Frame = +2
Query: 491 VHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINYYKFS 550
+HRDLAARN+L V + KISDFGL++ AD YY + P+KWY+PE I KFS
Sbjct: 2 IHRDLAARNIL-VDRSCVKISDFGLAQFANAD-GYYYGISQRDIPIKWYSPEAIETCKFS 175
Query: 551 SKSDVWSFGVLMWEAFSYGQKPY----RGMKGSEVTAMLEKGERMGCPAGCPREMY-DLM 605
S SDVWS+GV ++E FS G+ P + E L KGER+ P C +Y +LM
Sbjct: 176 SYSDVWSYGVTLFEMFSRGEIPNLLPGHDLTQEEFLNRLRKGERLPKPELCSDFVYSELM 355
Query: 606 NLCWTYDVENRPGFAAV 622
CW ++RP F +
Sbjct: 356 RPCWHEMPKSRPTFHQI 406
>08294
Length = 1849
Score = 97.8 bits (242), Expect = 1e-20, Method: Compositional matrix adjust.
Identities = 66/218 (30%), Positives = 96/218 (44%), Gaps = 13/218 (5%)
Frame = +2
Query: 430 PYIVRMIGIC-EAESWMLVMEMAELGPLNKYLQQNRHVKDK------------NIIELVH 476
P IV +G+C EAE L+ E + G L ++L R+ + + +
Sbjct: 887 PNIVHFMGVCREAEPHFLITEYCDWGDLKQFLLATRNDNGRGRGTRVPALALSQKLGMGQ 1066
Query: 477 QVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPV 536
QV+ GM+ L VH DLAARNVLL ++ K++ LS + A E Y Q P+
Sbjct: 1067 QVAAGMEALSNQGLVHGDLAARNVLLTSRMQLKVARPALSGDVYASEYYPLHQR--LVPL 1240
Query: 537 KWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAG 596
+W PE + ++ DVW+FGV +WE PYR M EV L+ +
Sbjct: 1241 RWLPPEGVLEDSATTCGDVWAFGVFLWEVLQLADLPYRLMSDEEVLRSLQHSQAALDSPD 1420
Query: 597 CPREMYDLMNLCWTYDVENRPGFAAVELRLRNYYYDVV 634
P + L+ C RP F+ + L DVV
Sbjct: 1421 APPALLSLLQRCTAQQPSQRPPFSEICSVLSLASTDVV 1534
>17637
Length = 447
Score = 84.0 bits (206), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 43/137 (31%), Positives = 73/137 (53%), Gaps = 1/137 (0%)
Frame = +1
Query: 499 NVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKW-PVKWYAPECINYYKFSSKSDVWS 557
N ++ Q K++D LS+ L + + Y G++ P+KW + E + ++ SDVWS
Sbjct: 1 NCVIDDQLRVKLTDSALSRDLFSGD--YNCLGDGEYRPIKWLSLEALQKSHYNEGSDVWS 174
Query: 558 FGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAGCPREMYDLMNLCWTYDVENRP 617
FGVLMWE + G+ PY + E+ L+ G R+ P CP E++ +M CW RP
Sbjct: 175 FGVLMWEMCTLGKLPYAEIDPYEMEHYLKDGYRLAQPFNCPDELFTIMAYCWASMPAERP 354
Query: 618 GFAAVELRLRNYYYDVV 634
F+ +++ L ++ +
Sbjct: 355 SFSQLQICLSEFHTQIT 405
>18921
Length = 697
Score = 81.6 bits (200), Expect = 8e-16, Method: Compositional matrix adjust.
Identities = 57/192 (29%), Positives = 101/192 (52%), Gaps = 3/192 (1%)
Frame = +2
Query: 376 ELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRM 435
+LG G++G+V K ++ +T V +K D L+ E++ E ++MQQ D+ YIV+
Sbjct: 50 KLGEGSYGSVFKSLHK-----ETGQVLAIKQVPVDTDLQ-EIIKEISIMQQCDSKYIVKY 211
Query: 436 IG--ICEAESWMLVMEMAELGPLNKYLQ-QNRHVKDKNIIELVHQVSMGMKYLEESNFVH 492
G + W +VME G ++ ++ +N+ + ++ I +++ G+ YL +H
Sbjct: 212 YGSYFKNTDLW-IVMEYCGAGSVSDIMRLRNKTLVEREIATILYYTLKGLXYLHSRRKIH 388
Query: 493 RDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINYYKFSSK 552
RD+ A N+LL + +AK++DFG++ L + K T P W APE I +
Sbjct: 389 RDIKAGNILLNNEGHAKLADFGVAGQLT--DTMAKRNTVIGTPY-WMAPEVIQEIGYDCV 559
Query: 553 SDVWSFGVLMWE 564
+D+WS G+ E
Sbjct: 560 ADIWSLGITALE 595
>01707
Length = 757
Score = 79.7 bits (195), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 51/214 (23%), Positives = 105/214 (49%), Gaps = 2/214 (0%)
Frame = +1
Query: 376 ELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRM 435
++G G++G V K + K+ + VA+K +DP +K + E +++QL +P +VR+
Sbjct: 85 KIGEGSYGVVFKC--RNKETSQLVAIKKFVESEDDPLIKKIAMREIRMLKQLKHPNLVRL 258
Query: 436 IGICEAESWM-LVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSMGMKYLEESNFVHRD 494
I + + + LV + + LN+ + R + + + +++Q + + + + N +HRD
Sbjct: 259 IEVFRRKKRLHLVFDYVDHTLLNELDRYPRGLPEPMVKRIIYQTLLAVNFCHQYNTIHRD 438
Query: 495 LAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPE-CINYYKFSSKS 553
+ N+L+ Q K+ DFG ++ L + Y +W + APE + ++
Sbjct: 439 VKPENILITRQGQVKLCDFGFARILTGPGDEYTDYVATRW---YRAPELLVGDTQYGPPV 609
Query: 554 DVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEK 587
DVW+ G + E + GQ + G + ++ K
Sbjct: 610 DVWAIGCVFAELLT-GQALWPGRSDVDQLHLIRK 708
>13305
Length = 549
Score = 78.6 bits (192), Expect = 8e-15, Method: Composition-based stats.
Identities = 34/98 (34%), Positives = 54/98 (55%)
Frame = +2
Query: 535 PVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCP 594
P++W A E + ++++SDVWSFGV++WE F+ G PY ++ A L+ G R+ P
Sbjct: 14 PIRWMAVESLFNNTYTTQSDVWSFGVVLWEIFTLGGTPYSSTDTQQLFAFLKDGYRLKRP 193
Query: 595 AGCPREMYDLMNLCWTYDVENRPGFAAVELRLRNYYYD 632
C + Y +M CW + + RP F + RL+ D
Sbjct: 194 KLCDQNTYAMMLQCWNENAQRRPTFPELCGRLQRMLDD 307
>00715
Length = 1788
Score = 78.2 bits (191), Expect = 8e-15, Method: Compositional matrix adjust.
Identities = 73/259 (28%), Positives = 112/259 (43%), Gaps = 38/259 (14%)
Frame = +1
Query: 397 KTVAVKILKNEANDP-ALK----DELLAEANVMQQLDNPYIVRMIGIC-----EAESWML 446
+TVAVKI +++P AL+ +ELLA ++ ++ +V ++G E +W+
Sbjct: 1 RTVAVKIYHKRSSNPRALRQSYSNELLAFRCGLRHVN---VVSILGATSLHRFEDGAWL- 168
Query: 447 VMEMAELGPLNKYLQQNRHVKDKNI---IELVHQVSMGMKYLEESNFVHRDLAARNVLLV 503
M +GPLN N H +D + + L Q++ G+ YL N VH DL N LL
Sbjct: 169 --AMEYVGPLNLQTILNDHQQDIDSSMRLSLALQMARGLHYLHSINIVHLDLKPANCLLT 342
Query: 504 TQHYAKISDFGLSKALR-------------ADENYYKAQTHGKW------PVKWYAPECI 544
+I+DFG L A G W + + APE +
Sbjct: 343 RDLKLRIADFGCCHQLTPTGLDMGEREGGMAGNELELTPVQGAWKNELAGTLAYRAPELL 522
Query: 545 NYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAGC----PRE 600
+ S +SDV+S G+ +W+ + Q PY G+ V + + CP P E
Sbjct: 523 KGLQPSVRSDVYSLGITLWQMCTR-QGPYEGVPAHAVVYQVVSKDLRPCPPPSTEDDPFE 699
Query: 601 MY--DLMNLCWTYDVENRP 617
+ DL CW VE+RP
Sbjct: 700 VMFRDLYTQCWARRVEDRP 756
>17253
Length = 483
Score = 76.6 bits (187), Expect = 3e-14, Method: Composition-based stats.
Identities = 48/155 (30%), Positives = 82/155 (52%), Gaps = 14/155 (9%)
Frame = -1
Query: 398 TVAVKILKNEANDPALKDELLAEANVMQQLD-NPYIVRMIGICE-AESWMLVMEMAELGP 455
TVAVK NEA A K E L E ++M++L +P +V +G C ++ +++ME G
Sbjct: 462 TVAVKT-HNEAATDAEKSEFLRELSIMRKLPRHPNVVSFMGCCTMSDPALILMEFCCHGD 286
Query: 456 LNKYLQQNR------------HVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLV 503
L +L++ R + ++ V+ GM ++ + VHRD+AARNVL+
Sbjct: 285 LLSFLRKRRPDRTVFLTSTANDLTARDFFSFALHVARGMAHVANNKIVHRDVAARNVLIS 106
Query: 504 TQHYAKISDFGLSKALRADENYYKAQTHGKWPVKW 538
++ K+SDFGLS+ + + Y+ + P++W
Sbjct: 105 ERNVCKVSDFGLSRRVGDQNDVYEIVSRRPLPLRW 1
>01718
Length = 959
Score = 75.1 bits (183), Expect = 8e-14, Method: Compositional matrix adjust.
Identities = 67/265 (25%), Positives = 128/265 (48%), Gaps = 16/265 (6%)
Frame = +3
Query: 375 KELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVR 434
+++G+G F V K +++ V +A+K+ +N + +L E ++ +L + I+R
Sbjct: 165 EKIGAGFFSEVFKVTHRITGQV--MALKMNTMTSN----RHNMLREVQLLNRLQHANILR 326
Query: 435 MIGICEAESWM-LVMEMAELGPLNKYLQQNRHVKDKNI-----IELVHQVSMGMKYLEES 488
+G+C E + + E G L + L++ KD+ + I+L ++ G+ YL +
Sbjct: 327 FMGVCVHEGQLHALTEYIPSGNLEQLLEK----KDEELPWTQRIQLTLGLARGLDYLHST 494
Query: 489 NFVHRDLAARNVLLVTQ----HYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECI 544
F+HRDL ++N+L+ + ++A I+DFGL+ + + K T G W APE +
Sbjct: 495 RFIHRDLTSKNILIRREDNHGYHAVIADFGLATKIPDPLDKEKLPTVGS--PYWMAPEVL 668
Query: 545 NYYKFSSKSDVWSFGVLMWEAFSY-----GQKPYRGMKGSEVTAMLEKGERMGCPAGCPR 599
N + ++ ++D++S G++M E + P G + A+ E + CP
Sbjct: 669 NGHFYNERADLFSVGIIMCEITARIPADPDIMPRMNNFGVDYVALSEM------ISYCPL 830
Query: 600 EMYDLMNLCWTYDVENRP-GFAAVE 623
+ L C D + RP G +E
Sbjct: 831 DYLQLAFKCCQVDPQKRPRGVEIIE 905
>13066
Length = 551
Score = 68.6 bits (166), Expect = 9e-12, Method: Compositional matrix adjust.
Identities = 52/182 (28%), Positives = 86/182 (47%), Gaps = 5/182 (2%)
Frame = +3
Query: 383 GTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLA-EANVMQQLDNPYIVRMIGICE- 440
GT GY + K+ A KI+ E ++ E +++ +LD+PYI+++ I +
Sbjct: 24 GTFNDGYGRNIKL----ACKIIDKEKAPVDFVEKFFPRELDLLTKLDHPYIIQIHSILQR 191
Query: 441 AESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNV 500
+ M AE G L Y+Q+ VK+K +Q++ + YL + HRDL N+
Sbjct: 192 XPKNFIFMRFAERGDLLTYIQEVGFVKEKQAKIWFYQMTTALNYLHSYDVAHRDLKCENI 371
Query: 501 LLVTQHYAKISDFGLSKAL--RADENYYKAQTHGKWPVKWYAPECINYYKFSSK-SDVWS 557
LL + K++DFG + A + E Y G + APE + ++ K +D WS
Sbjct: 372 LLSSHFNVKLADFGFACACITESGEKYMSRTYCGS--AAYAAPEIVYGAPYAPKVADAWS 545
Query: 558 FG 559
G
Sbjct: 546 LG 551
>19301
Length = 712
Score = 67.0 bits (162), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 43/143 (30%), Positives = 73/143 (51%), Gaps = 3/143 (2%)
Frame = +2
Query: 377 LGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANV--MQQLDNPYIVR 434
LGSG G V G K + VAVK +++ + E ++ +++L++P I+
Sbjct: 329 LGSGAQGAVFLG----KLCAEEVAVKKVRD-----------IKETDIRNLRKLNHPNIIS 463
Query: 435 MIGIC-EAESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSMGMKYLEESNFVHR 493
G+C +A + ++ME G L + L+ + + +++ Q++ GM YL +HR
Sbjct: 464 FKGVCTQAPCYCIIMEYCPYGQLYEVLRDGKEIPPALVLDWSKQIASGMNYLHSHKIIHR 643
Query: 494 DLAARNVLLVTQHYAKISDFGLS 516
DL + NVL+ KISDFG S
Sbjct: 644 DLKSPNVLVAKNDVVKISDFGTS 712
>01756
Length = 1858
Score = 66.2 bits (160), Expect = 3e-11, Method: Compositional matrix adjust.
Identities = 51/203 (25%), Positives = 91/203 (44%), Gaps = 11/203 (5%)
Frame = -3
Query: 376 ELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRM 435
++G G FG V K + KK + VA+K + + L E ++Q L++ +V +
Sbjct: 1721 KIGQGTFGEVFKA--RCKKTKQVVAMKKVLMDNEKEGFPITALREIKILQLLNHENVVDL 1548
Query: 436 IGICEAES---------WMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSMGMKYLE 486
I IC ++ + LV E E + I E++ Q+ G+ Y+
Sbjct: 1547 IEICSTKATSANRYKSMFYLVFEFCEHDLAGLLSNMSVVFNLPEIKEVMKQLMNGLYYIH 1368
Query: 487 ESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPE--CI 544
+ +HRD+ A N+L+ Q K++DFGL++A + T+ + WY P +
Sbjct: 1367 RNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTN-RVVTLWYRPPELLL 1191
Query: 545 NYYKFSSKSDVWSFGVLMWEAFS 567
+S+ D W G +M E ++
Sbjct: 1190 GDRNYSTAIDQWGAGCIMAEMWT 1122
>12721
Length = 821
Score = 66.2 bits (160), Expect = 4e-11, Method: Compositional matrix adjust.
Identities = 43/171 (25%), Positives = 76/171 (44%), Gaps = 7/171 (4%)
Frame = +1
Query: 414 KDELLAEANVMQQLDNPYIVRMIG--ICEAESWMLVMEMAELGPLNKYLQQNRHVKDKNI 471
++ L E VM+ +P IV M + E W +VME E G L + NR + + I
Sbjct: 208 RELLFNEVVVMRDYHHPNIVEMYNSYLVNDELW-VVMEFMEGGALTDIVTNNR-MDEVQI 381
Query: 472 IELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTH 531
+ + +L + +HRD+ + ++LL K+ DFG + D K+
Sbjct: 382 ATVCRACLKALAFLHANGVIHRDIKSDSILLSHDGKVKLXDFGFCAQVTQDLQKRKSLVG 561
Query: 532 GKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFS-----YGQKPYRGMK 577
+ W APE I+ + + D+WS G+++ E + + P + M+
Sbjct: 562 TPY---WMAPEVISRLPYGPEVDIWSLGIMVMEMIDAEPPFFNEPPLQAMR 705
>14420
Length = 528
Score = 65.5 bits (158), Expect = 7e-11, Method: Compositional matrix adjust.
Identities = 45/162 (27%), Positives = 78/162 (48%), Gaps = 2/162 (1%)
Frame = +2
Query: 414 KDELLAEANVMQQLDNPYIVRMIG--ICEAESWMLVMEMAELGPLNKYLQQNRHVKDKNI 471
K+ ++ E VM++ NP IV + + E W +VME G L + + + + I
Sbjct: 32 KELIINEILVMRENQNPNIVNYLDSYLVGEELW-VVMEFLAGGSLTDVVTET-CMDEGQI 205
Query: 472 IELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTH 531
+ + +++L E+ +HRD+ + N+LL K++DFG L +++ K T
Sbjct: 206 AAVCRECLQALEFLHENQVIHRDIKSDNILLGMDGSVKLTDFGFCAQLSPEQS--KRSTM 379
Query: 532 GKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPY 573
P W APE + ++ D+WS GV+ E G+ PY
Sbjct: 380 VGTP-YWMAPEVVTRKQYGPTVDIWSLGVMCIEMIE-GEPPY 499
>09606
Length = 1300
Score = 64.7 bits (156), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 55/221 (24%), Positives = 97/221 (43%), Gaps = 20/221 (9%)
Frame = -3
Query: 375 KELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVR 434
+ELG G + KG + K + VA+ ++ + E+ + + +P +V+
Sbjct: 1097 EELGKGEHSIIYKG--RRKGTINFVAIHCIEK-----CKRPEVTNTVRMTHDISHPNVVQ 939
Query: 435 MIGICEAESWM-LVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSMGMKYLEESNFVHR 493
E + + LV+E+ G L L Q+ H+ + +I + + G+ Y+ +
Sbjct: 938 FHEWYETSNHLWLVVELCTGGSLADILAQDHHLPETSIRDFGIHLVTGLHYIHSLGILFH 759
Query: 494 DLAARNVLLVTQHYAKISDFGLSKA--LRADENYYK-AQTHGKWPVK------------- 537
DL VLL T K +DFGLSK +E ++K A+ +W ++
Sbjct: 758 DLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAGDQWNIQSAEEMMKQVPTSG 579
Query: 538 ---WYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRG 575
+ APE + S SD+W+ G + +E FS G P+ G
Sbjct: 578 SPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFS-GHPPFLG 459
>21079
Length = 878
Score = 63.2 bits (152), Expect = 3e-10, Method: Compositional matrix adjust.
Identities = 42/146 (28%), Positives = 75/146 (51%), Gaps = 3/146 (2%)
Frame = +1
Query: 443 SWMLVMEMAELGPL-NKYLQQNRHVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVL 501
+ +LVME G L + ++ + + +++ + V Q+ G+ Y+ + +H DL NVL
Sbjct: 46 TMVLVMEFVGAGELFERVIRDDFVLTERDCVHFVRQICSGVGYMHTQSILHLDLKPENVL 225
Query: 502 LVTQHY--AKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFG 559
V+ + KI DFGL++ + ++ Q P ++ APE +NY + + +D+WS G
Sbjct: 226 CVSDNSNQIKIIDFGLARFYKPGDSL---QVLFGTP-EFIAPEVVNYDEINFTTDMWSIG 393
Query: 560 VLMWEAFSYGQKPYRGMKGSEVTAML 585
V+ + S G+ S VT ML
Sbjct: 394 VICYILLS-------GLSPSRVTTML 450
>18484
Length = 635
Score = 61.6 bits (148), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 41/150 (27%), Positives = 75/150 (50%), Gaps = 1/150 (0%)
Frame = +1
Query: 460 LQQNRHVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSK-A 518
+QQ K+ ++++G+ +L + ++RDL NV+L ++ + KI+DFG+ K
Sbjct: 16 IQQEGKFKEPVAAFYAAEIAVGLFFLHDQGIIYRDLKLDNVMLDSEGHIKIADFGMCKEG 195
Query: 519 LRADENYYKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKG 578
+ D +T P + APE + Y +S D W++GVL++E + GQ P+ G
Sbjct: 196 MTGDAT---TRTFCGTP-DYIAPEIVLYQPYSKSVDWWAYGVLLFEMLA-GQPPFDGEDE 360
Query: 579 SEVTAMLEKGERMGCPAGCPREMYDLMNLC 608
E+ + + + P RE ++LC
Sbjct: 361 DELFSSITD-HNVSYPKAMSREA---VSLC 438
>00300
Length = 2318
Score = 61.2 bits (147), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 48/246 (19%), Positives = 106/246 (43%), Gaps = 5/246 (2%)
Frame = -1
Query: 376 ELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRM 435
++G G FG V + +A+K +K + ND E+ E + + + + +V+
Sbjct: 1637 KIGEGQFGKVYTAVNM--STGELMALKEMKFQPNDLQQLREMCDEIKIFEGIQHENLVKY 1464
Query: 436 IGI-CEAESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSMGMKYLEESNFVHRD 494
G+ + ++ ME + G + + + + + I ++ + + +L E++ VHRD
Sbjct: 1463 YGVEVHKDEMLMFMEYCDTGTIEEAAKMG--LPEYLIRRYTREIVLAVNHLHENSIVHRD 1290
Query: 495 LAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINYYK---FSS 551
+ N+ L + + K+ DFG S L++ + + APE +
Sbjct: 1289 IKGANIFLTSNGHVKLGDFGCSVKLKSHTTMPGEFHNLVGTTAYMAPEVFTQNDQGGYGR 1110
Query: 552 KSDVWSFGVLMWEAFSYGQKPYRGMKGS-EVTAMLEKGERMGCPAGCPREMYDLMNLCWT 610
+D+WS G ++ E + G++P+ + + ++ + G + P E ++L
Sbjct: 1109 AADIWSLGCVVIE-MATGKRPWHDLDNNYQIMYKVGIGHKPAVPDSLSVEGKHFLDLIMC 933
Query: 611 YDVENR 616
+D R
Sbjct: 932 HDPAQR 915
>01060
Length = 1800
Score = 60.5 bits (145), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 48/192 (25%), Positives = 93/192 (48%), Gaps = 5/192 (2%)
Frame = +1
Query: 375 KELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVR 434
+++G G +G V K + + + +A+K ++ ++ + + E ++++L + IV
Sbjct: 91 QKIGEGTYGVVYKCRH--RATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTNIVC 264
Query: 435 MIG-ICEAESWMLVMEMAELGPLNKYLQQNRH--VKDKNIIE-LVHQVSMGMKYLEESNF 490
+ I E E LV E + L Y+ + V D+ +++ V Q+ G+ + +
Sbjct: 265 LEDVIMEDERLFLVFEFLSMD-LKMYIDKFPEGVVLDRRLVKSYVFQIVTGIXFCHQRRI 441
Query: 491 VHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECI-NYYKF 549
VHRDL +N+L+ KI+DFG+++ Y + W + APE + K+
Sbjct: 442 VHRDLKPQNLLINHTGAIKIADFGMARTFALPVRAYTHEVVTLW---YRAPEILMGASKY 612
Query: 550 SSKSDVWSFGVL 561
S+ DVWS G +
Sbjct: 613 STPVDVWSIGTI 648
>14126
Length = 1265
Score = 60.5 bits (145), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 51/202 (25%), Positives = 103/202 (50%), Gaps = 11/202 (5%)
Frame = +3
Query: 377 LGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQLD---NPYIV 433
+G+G +GTV K ++ + VA+K ++ + + + E ++++QL+ +P +V
Sbjct: 213 IGNGAYGTVYKAR-DLRNQGEFVAMKRIRLNNTEEGMPMMAIREISMLKQLEQYEHPNVV 389
Query: 434 RMIG-----ICEAESWM-LVMEMAELGPLNKYLQQ--NRHVKDKNIIELVHQVSMGMKYL 485
R++ I + E + LV E E L YL + + + I +L+ Q+ G+ +L
Sbjct: 390 RLLDVSHNTITDREIRLNLVFEYIE-HDLATYLAKCPSPGLGPDRIKDLMLQLLNGVDFL 566
Query: 486 EESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECIN 545
+ VHRDL +N+L+ K++DFGL++ +++ A T + + +PE +
Sbjct: 567 HSNRIVHRDLKPQNLLISKDGRLKLADFGLARIY----SFHMALTTVVVTLWYRSPEVLM 734
Query: 546 YYKFSSKSDVWSFGVLMWEAFS 567
++ + D+WS G + E F+
Sbjct: 735 QAEYGTSVDIWSCGCIFAELFT 800
>13212
Length = 1067
Score = 59.7 bits (143), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 45/160 (28%), Positives = 70/160 (43%), Gaps = 9/160 (5%)
Frame = -1
Query: 470 NIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQ 529
I + H++ M + +L + +HRD+ A NVLL K++DFG+S + + K
Sbjct: 977 QICYVCHEMCMALDFLHRHHVIHRDIKAGNVLLTIDGEVKLADFGVSA--KNTQTQQKRD 804
Query: 530 THGKWPVKWYAPECI-------NYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVT 582
T P W APE + Y F K+D+WS GV + E F+ + P + M V
Sbjct: 803 TFIGTPY-WMAPEVVLCETLKDTPYDF--KADIWSLGVTLIE-FAQIEPPNKEMHPMRVL 636
Query: 583 AMLEKGE--RMGCPAGCPREMYDLMNLCWTYDVENRPGFA 620
+ K + + P + D + C D RP A
Sbjct: 635 IKIHKSDPPTLEKPKKWTKLFKDFIAKCLVKDPNLRPTAA 516
>31885
Length = 529
Score = 58.5 bits (140), Expect = 9e-09, Method: Compositional matrix adjust.
Identities = 42/170 (24%), Positives = 82/170 (48%), Gaps = 6/170 (3%)
Frame = -2
Query: 421 ANVMQQLDNPYIVRM-IGICEAESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVS 479
+++ +LD+P++V + + E +V+++ G L ++QQ ++ + + Q++
Sbjct: 519 VDMLTRLDHPFLVNLWYAFQDEEDLFMVVDLFLGGDLRYHMQQEVSFREDCVKFYLCQLA 340
Query: 480 MGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWY 539
+ + YL VHRD+ N+LL Q + ++DF ++ L DE T G P +
Sbjct: 339 LVLDYLRSQKIVHRDIKPDNILLDEQGHCHVTDFNIATQLEDDE--LATSTSGTRP--YM 172
Query: 540 APEC----INYYK-FSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAM 584
APE IN + + D WS GV ++E ++P+ + + M
Sbjct: 171 APEVYGVAINERRGYGFPVDWWSLGVSLFELLK-KRRPFSVHSNTSLHEM 25
>19094
Length = 898
Score = 56.6 bits (135), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 31/103 (30%), Positives = 54/103 (52%)
Frame = +1
Query: 462 QNRHVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRA 521
+N+ + ++ I +++ G+ YL +HRD+ A N+LL + +AK++DFG++ L
Sbjct: 37 RNKTLVEREIATILYYTLKGL*YLHSRRKIHRDIKAGNILLNNEGHAKLADFGVAGQL-- 210
Query: 522 DENYYKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWE 564
+ K T P W APE I + +D+WS G+ E
Sbjct: 211 TDTMAKRNTVIGTPY-WMAPEVIQEIGYDCVADIWSLGITALE 336
>04591
Length = 1117
Score = 56.2 bits (134), Expect = 4e-08, Method: Compositional matrix adjust.
Identities = 55/221 (24%), Positives = 96/221 (43%), Gaps = 14/221 (6%)
Frame = -2
Query: 418 LAEANVMQQLDNPYIVRMIGICEAE---------SWMLVMEMAE--LGPLNKYLQQNRHV 466
L E ++QQL++ +V++ IC + ++ L+ E + L L L+ +
Sbjct: 1077 LREIKILQQLEHENVVQLQEICHTQAGPYNRYKSTFYLIFEYCDYDLAGLLNNLRVKFSL 898
Query: 467 KDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYY 526
DK L+ Q+ G+ Y+ +HRD+ A N+LL K++DFGLS+ +
Sbjct: 897 ADKK--NLMSQLLNGLFYIHTKQILHRDIKAANILLTRDGVLKLADFGLSRP------WV 742
Query: 527 KAQTHGKWPVK-WYAPE--CINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTA 583
K++ V WY P + ++ + D+W G +M E +S +KP M+G
Sbjct: 741 KSKRLTNRVVTLWYRPPELLLGEREYGPEIDMWGVGCIMAEMWS--RKPL--MQGRSEQH 574
Query: 584 MLEKGERMGCPAGCPREMYDLMNLCWTYDVENRPGFAAVEL 624
L + +LC + + E PG +EL
Sbjct: 573 QLSL----------------ITDLCGSLNAEVWPGVTKLEL 499
>29581
Length = 1278
Score = 55.5 bits (132), Expect = 7e-08, Method: Compositional matrix adjust.
Identities = 44/135 (32%), Positives = 65/135 (48%), Gaps = 4/135 (2%)
Frame = -2
Query: 442 ESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVL 501
+S LVME E + + + +V Q+ G++YL E+ +HRDL N+L
Sbjct: 1130 DSLFLVMEYCEQDLASLLDNMPAPFSESQVKCIVLQLLKGLRYLHEAFIIHRDLKVSNLL 951
Query: 502 LVTQHYAKISDFGLSKALRADENYYKAQ--THGKWPVKWY-APECINYYKFSSKS-DVWS 557
+ + KI+DFGL++ NY K Q K WY APE + K S + D+WS
Sbjct: 950 MTDKGCVKIADFGLAR------NYGKPQKPMTPKVVTLWYRAPELLFGSKTHSTAIDMWS 789
Query: 558 FGVLMWEAFSYGQKP 572
G ++ E G KP
Sbjct: 788 AGCILGELL--GHKP 750
>12672
Length = 773
Score = 54.3 bits (129), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 43/177 (24%), Positives = 79/177 (44%), Gaps = 14/177 (7%)
Frame = +3
Query: 473 ELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFG-LSKALRADENYYKAQTH 531
++V + G++YL ++ VHRD+ N+LL +++ AK+ DF + A + + +
Sbjct: 3 KIVKGTASGIQYLNDNGHVHRDIKTANILLDSEYTAKVGDFATVVSAPSGEGKTVQNASV 182
Query: 532 GKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFS--YGQKPYRGMK--GSEVTAMLEK 587
+ APE I ++ S+K D +SFGV++ E + Q R + S + +E+
Sbjct: 183 VIGTAAYLAPEAI-HFDVSTKLDSYSFGVVLLEVITGLVAQDYSREERTLSSHIMENVEE 359
Query: 588 GERM---------GCPAGCPREMYDLMNLCWTYDVENRPGFAAVELRLRNYYYDVVN 635
E + P G ++YD+ C + RP + L +VN
Sbjct: 360 PEEIHDFVDQSAGTWPDGAVDKLYDISMRCLNLSKKQRPNVKDIRPELEEL*GCIVN 530
>17806
Length = 433
Score = 53.9 bits (128), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 43/123 (34%), Positives = 67/123 (54%), Gaps = 12/123 (9%)
Frame = +1
Query: 375 KELGSGNFGTVKKGYYQ--MKKVVKT-VAVKILKNEANDPALKDELLA---EANVMQQLD 428
KELG+G FG V + + V ++ V VK+LK D A KDE L E ++LD
Sbjct: 67 KELGTGWFGKVIESDAERITTGVSRSKVVVKMLK----DDATKDEQLLFFEEVAPFRELD 234
Query: 429 NPYIVRMIGIC-EAESWMLVMEMAELGPLNKYLQQNRH-----VKDKNIIELVHQVSMGM 482
+P IVR++G C E +++ME A LG L +YL+ +RH ++ +++ +S G+
Sbjct: 235 HPNIVRLLGQCTEMNPMLMLMECAALGNLKQYLRNHRHQQAMLIQKNRLLKFAMDISSGL 414
Query: 483 KYL 485
L
Sbjct: 415 ACL 423
>27546
Length = 426
Score = 50.4 bits (119), Expect = 2e-06, Method: Composition-based stats.
Identities = 26/102 (25%), Positives = 52/102 (50%), Gaps = 1/102 (0%)
Frame = -1
Query: 420 EANVMQQLDNPYIVRMIGICE-AESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQV 478
E ++ +LD+P I+++ I + + M AE G + ++++ + + Q+
Sbjct: 330 ELEILTRLDHPNIIQIHSILQRGPKIFIFMRYAEKGDMLSHIKKTGPIDEAQTKVWFFQM 151
Query: 479 SMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALR 520
+ ++YL + HRDL N+LL + KI+DFG ++ R
Sbjct: 150 AKALQYLHSHDIAHRDLKCENILLSKRLNVKIADFGFARYCR 25
>25550
Length = 941
Score = 49.3 bits (116), Expect(2) = 2e-06, Method: Compositional matrix adjust.
Identities = 23/58 (39%), Positives = 33/58 (56%)
Frame = +3
Query: 573 YRGMKGSEVTAMLEKGERMGCPAGCPREMYDLMNLCWTYDVENRPGFAAVELRLRNYY 630
Y G+ +EV +LE+G RM P G P ++Y LM CW +D + RP F + L N +
Sbjct: 42 YPGVDLTEVYHLLERGYRMERPQGTPADVYILMLKCWQWDPKERPTFKEIHYLLENMF 215
Score = 20.4 bits (41), Expect(2) = 2e-06, Method: Compositional matrix adjust.
Identities = 8/17 (47%), Positives = 10/17 (58%)
Frame = +1
Query: 559 GVLMWEAFSYGQKPYRG 575
GVL+WE +YG G
Sbjct: 1 GVLLWELATYGMSLTLG 51
>19761
Length = 473
Score = 49.7 bits (117), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 31/147 (21%), Positives = 69/147 (46%), Gaps = 2/147 (1%)
Frame = -3
Query: 468 DKNIIELVHQVSMGMKYLEESN--FVHRDLAARNVLLVTQHYAKISDFGLSKALRADENY 525
++ I+ + Q + + Y+ +HRDL +N+ + + ++ D GL++ L ++
Sbjct: 426 ERLIVCWLMQTASALNYMHTHTPVILHRDLKPQNIYVTEKGDVRLGDLGLARKLTGPADF 247
Query: 526 YKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAML 585
+Q + + +PE ++ ++SKSD+WS G + ++ G+K M + +
Sbjct: 246 ATSQVG---TIMYLSPEILSQQPYNSKSDIWSLGCVFYDI--TGKKGSDEMGVMFLLVQV 82
Query: 586 EKGERMGCPAGCPREMYDLMNLCWTYD 612
G ++ P +E D ++ T D
Sbjct: 81 MGGRKLPLPDHYSQEFRDTISRMLTKD 1
>07833
Length = 1504
Score = 49.7 bits (117), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 46/218 (21%), Positives = 94/218 (43%), Gaps = 8/218 (3%)
Frame = -3
Query: 413 LKDELLAEANVMQQLDNPYIVRMIGIC-EAESWMLVMEMAELGPLNKYLQ-QNRHVKDKN 470
+ + + E ++ ++P ++ ++ C + + +L+ + G L L ++ V D+N
Sbjct: 1490 ITRDFMEEFPRLRIFNHPNVLPVLACCNQPPNLVLISQFMPFGSLYNTLHGESGIVVDQN 1311
Query: 471 -IIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQ 529
+ ++ GM++L + N LL ++H + D L+ + + +
Sbjct: 1310 QSLRFAMDIARGMEFLHSM-----EPTIPNFLLTSKHV--MIDEDLTARINMADYCFSFH 1152
Query: 530 THGK-WPVKWYAPECINYYK---FSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAML 585
GK + W APE + + +D+WSF +LMWE + P+ + EV +
Sbjct: 1151 EKGKVYSPAWMAPEALQRRPDDINTRAADMWSFAILMWE-LETREVPFAELSSMEVGMKV 975
Query: 586 E-KGERMGCPAGCPREMYDLMNLCWTYDVENRPGFAAV 622
+G R+ P G M L+ +C + RP F +
Sbjct: 974 ALEGLRISIPPGISLHMSRLIKICMNEEPGKRPRFDMI 861
>26560
Length = 398
Score = 48.9 bits (115), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 32/120 (26%), Positives = 59/120 (49%), Gaps = 1/120 (0%)
Frame = -1
Query: 456 LNKYLQQNRHVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGL 515
L+ +L Q+ +K + +V +G++++ V+RDL N+LL + +ISD GL
Sbjct: 395 LHYHLSQHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLGL 216
Query: 516 SKALRADENYYKAQTHGKWPVKWYAPECI-NYYKFSSKSDVWSFGVLMWEAFSYGQKPYR 574
+ + THG + APE + + S +D +SFG ++++ G P+R
Sbjct: 215 ACDFSKKRPHASVGTHG-----YMAPEVLMKGQSYDSSADWFSFGCMLYKLLK-GHSPFR 54
>30755
Length = 1137
Score = 48.9 bits (115), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 37/142 (26%), Positives = 61/142 (42%)
Frame = +2
Query: 477 QVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPV 536
++ + YL ++RDL N+LL + K++DFGL K D Y +
Sbjct: 56 EIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCK---EDITYGRTTKTFCGTP 226
Query: 537 KWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAG 596
++ APE ++ + D W GV+M+E G+ P+ + +V L E + P
Sbjct: 227 EYLAPEVLDDNDYGRAVDWWGTGVVMYEMIC-GRLPFYN-RDHDVLFTLILVEDVKFPRN 400
Query: 597 CPREMYDLMNLCWTYDVENRPG 618
E L++ D NR G
Sbjct: 401 ITDEAKSLLSGLLAKDPRNRLG 466
>27405
Length = 532
Score = 47.0 bits (110), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 35/150 (23%), Positives = 70/150 (46%), Gaps = 1/150 (0%)
Frame = -3
Query: 396 VKTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRMIGICEA-ESWMLVMEMAELG 454
+K + K +K + + +E + + V +P+IV M + E ++++ G
Sbjct: 476 MKCLDKKRIKMKGGETLALNERIMLSLVSTGEGSPFIVCMTYAFQTPEKLCFILDLMNGG 297
Query: 455 PLNKYLQQNRHVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFG 514
L+ +L Q+ +K + +V +G++++ V+RDL N+LL + +ISD G
Sbjct: 296 DLHYHLSQHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLDENGHVRISDLG 117
Query: 515 LSKALRADENYYKAQTHGKWPVKWYAPECI 544
L+ + + THG + APE +
Sbjct: 116 LACDFSKKKPHASVGTHG-----YMAPEVL 42
>01966
Length = 1735
Score = 46.6 bits (109), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 40/169 (23%), Positives = 78/169 (46%), Gaps = 4/169 (2%)
Frame = -1
Query: 397 KTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRMIG-ICEAESWMLVMEMAELGP 455
+ +A+K ++ ++ + + E ++++L + IV + I E E LV E +
Sbjct: 1633 RKLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTNIVCLEDVIMEDERLFLVFEFLSMD- 1457
Query: 456 LNKYLQQNRH--VKDKNIIE-LVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISD 512
L Y+ + V D+ +++ V Q+ G+ + + VHRDL +N+L+ KI+D
Sbjct: 1456 LKMYIDKFPEGVVLDRRLVKSYVFQIVTGINFCHQRRIVHRDLKPQNLLINHTGAIKIAD 1277
Query: 513 FGLSKALRADENYYKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFGVL 561
FG+++ Y + W + APE + + S W+ G L
Sbjct: 1276 FGMARTFALPVRAYTHEVVTLW---YRAPEILMGPQ--STPPXWTCGAL 1145
>03240
Length = 1683
Score = 46.6 bits (109), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 48/187 (25%), Positives = 86/187 (45%), Gaps = 11/187 (5%)
Frame = -3
Query: 358 IRPKEVYLDRKLLTLEDKELGSGNFGTV---KKG----YYQMKKVVKTVAVKILKNEAND 410
IR K +D K + + K LG G FG V +K Y MK + K+ +K +N+
Sbjct: 1321 IRLKRAKMD-KCMFEKIKTLGVGAFGEVSLCRKNDTGMLYAMKTLRKSDVLK--RNQVAH 1151
Query: 411 PALKDELLAEANVMQQLDNPYIVRMIGICEAESWM-LVMEMAELGPLNKYLQQNRHVKDK 469
+ ++LAEA DN ++V++ + +++ VM+ G L L + + +
Sbjct: 1150 VKAERDILAEA------DNEWVVKLYYSFQDHNYLYFVMDYVPGGDLMGLLIRMEILDEP 989
Query: 470 NIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADEN---YY 526
V ++ ++ + F+HRD+ N+L+ + K++DFGL R N Y
Sbjct: 988 LARFYVAELVQAIESVHRMGFIHRDIKPDNILIDRNGHIKLTDFGLCTGFRWTHNSKYYQ 809
Query: 527 KAQTHGK 533
+ TH +
Sbjct: 808 RDGTHAR 788
>15910
Length = 1361
Score = 45.8 bits (107), Expect = 5e-05, Method: Compositional matrix adjust.
Identities = 34/125 (27%), Positives = 60/125 (48%), Gaps = 3/125 (2%)
Frame = +2
Query: 468 DKNIIELVHQVSMGMKYLEESNFVHRDLAARNVL---LVTQHYAKISDFGLSKALRADEN 524
+K+ + + G++Y+ + VHRDL N+L + K++DFGLS+ + E
Sbjct: 461 EKDAARAISDILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLADFGLSRII---EP 631
Query: 525 YYKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAM 584
+ T P + APE + K++ D+WS GV+ + G +P+ E+
Sbjct: 632 EVQMSTVCGTP-GYCAPEVLKGDKYTPSVDMWSVGVIAYILLC-GYEPFFAENEFEMYRK 805
Query: 585 LEKGE 589
+ KGE
Sbjct: 806 IIKGE 820
>07836
Length = 1478
Score = 45.8 bits (107), Expect = 5e-05, Method: Compositional matrix adjust.
Identities = 37/140 (26%), Positives = 66/140 (47%), Gaps = 18/140 (12%)
Frame = -1
Query: 443 SW---MLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSMGMKYLEESNF--------V 491
SW L+ + E G L+ YL +R + ++ L H G+ +L F
Sbjct: 1340 SWTQLFLITDYHENGSLHDYLL-SRVLDSSEMLALAHSAICGLAHLHIEIFGTRGKPAIA 1164
Query: 492 HRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWY-APEC----INY 546
HRD+ ++N+L+ I+D GL+ ++ N + + K Y APE +N
Sbjct: 1163 HRDIKSKNILVKKNGTCCIADLGLAVRYISESNEVDVAPNPRQGTKRYMAPEVLEMLLNV 984
Query: 547 YKFSS--KSDVWSFGVLMWE 564
F + ++D+++FG++MWE
Sbjct: 983 KNFDAFKQADMYAFGLVMWE 924
>26711
Length = 405
Score = 45.8 bits (107), Expect = 5e-05, Method: Composition-based stats.
Identities = 33/110 (30%), Positives = 52/110 (47%), Gaps = 3/110 (2%)
Frame = -2
Query: 474 LVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKIS--DFGLSKALRA-DENYYKAQT 530
+V QV ++++ VH DL N+LL + DFGL++ L E + T
Sbjct: 401 VVKQVLDILQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARKLYPPQETFLNHGT 222
Query: 531 HGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSE 580
G + +PE ++ S+ SDVW GVL + S GQ P++ +E
Sbjct: 221 PG-----FTSPEALDVKPISTASDVWGVGVLAYILLS-GQSPFQADSATE 90
>28157
Length = 400
Score = 45.4 bits (106), Expect = 8e-05, Method: Compositional matrix adjust.
Identities = 40/126 (31%), Positives = 61/126 (48%), Gaps = 8/126 (6%)
Frame = +3
Query: 397 KTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRMIGICEAESWMLVMEMAELGPL 456
K VAVK +++E K + E + ++ +P IV + G C LVME AE G L
Sbjct: 3 KDVAVKRIESEQE----KKSFMQELKQLSRVSHPNIVCLYGACRDHPVCLVMEYAEGGSL 170
Query: 457 NKYLQ----QNRHVKDKNIIELVHQVSMGMKYL---EESNFVHRDLAARNVLLV-TQHYA 508
L Q ++ + L+ Q ++G++YL + +HRDL N+LL+
Sbjct: 171 YNVLHGSGPQPQYTAAHAMNWLL-QCALGVEYLHGMKPKALIHRDLKPPNLLLIQCGTKL 347
Query: 509 KISDFG 514
KI DFG
Sbjct: 348 KICDFG 365
>04138
Length = 800
Score = 44.7 bits (104), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 24/86 (27%), Positives = 43/86 (50%), Gaps = 2/86 (2%)
Frame = +1
Query: 484 YLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPE- 542
Y+ + +HRD+ A N+L+ Q K++DFGL++A + T+ + WY P
Sbjct: 58 YIHRNKILHRDMKAANILITKQGVLKLADFGLARAFSVNLRQPNRYTN-RVVTLWYRPPE 234
Query: 543 -CINYYKFSSKSDVWSFGVLMWEAFS 567
+ +S+ D W G +M E ++
Sbjct: 235 LLLGDRNYSTAIDQWGAGCIMAEMWT 312
>01392
Length = 1806
Score = 43.9 bits (102), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 30/130 (23%), Positives = 57/130 (43%), Gaps = 13/130 (10%)
Frame = -1
Query: 465 HVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHY-----AKISDFGLSKAL 519
H+ ++ +V ++ + +L HRDL N+L +H KI DF L+ +
Sbjct: 1803 HLCEREASLVVRHIARALDFLHSKGIAHRDLKPENIL--CEHLDDVVPVKICDFDLASGI 1630
Query: 520 RADENYYKAQTHGKWPV---KWYAPECI-----NYYKFSSKSDVWSFGVLMWEAFSYGQK 571
D + K PV ++ APE + + + + + D+WS G++++ G
Sbjct: 1629 SCDGDGTKTPELLT-PVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILYIMLC-GYP 1456
Query: 572 PYRGMKGSEV 581
P+ G G +
Sbjct: 1455 PFYGQCGEDC 1426
>11228
Length = 2155
Score = 43.1 bits (100), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 26/80 (32%), Positives = 41/80 (51%)
Frame = -2
Query: 5 GMADSANHLPFFFGNITREEAEDYLVQGGMSDGLYLLRQSRNYLGGFALSVAHGRKAHHY 64
G + LP+F +++EEA + L+ G +G +L+RQS NY G ++L + +
Sbjct: 1494 GDYEPVESLPYFHSCLSKEEAVEKLMLAG--EGSFLVRQSENYPGDYSLFFLCEKDVRRF 1321
Query: 65 TIERELNGTYAIAGGRTHAS 84
IER G + GGR S
Sbjct: 1320 RIERR--GNQFLVGGRLFDS 1267
>12786
Length = 460
Score = 42.4 bits (98), Expect = 6e-04, Method: Compositional matrix adjust.
Identities = 30/119 (25%), Positives = 51/119 (42%), Gaps = 20/119 (16%)
Frame = -3
Query: 481 GMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYA 540
+K L +H DL N +LV + K+ DFG++ L+ D+ + P + +
Sbjct: 374 AVKALHNEGVIHSDLKPANFMLVAGNL-KLIDFGIANTLQQDKTSVLKDSRVGTP-SYMS 201
Query: 541 PECINY--------------------YKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGS 579
PE I YK +SDVWS G +++ YG+ P++ +K +
Sbjct: 200 PEAIMAACDDSADDSMEEDGHRTKPKYKVGVRSDVWSLGCILYN-MVYGRTPFQHIKNN 27
>11185
Length = 473
Score = 42.0 bits (97), Expect = 7e-04, Method: Compositional matrix adjust.
Identities = 32/112 (28%), Positives = 51/112 (45%), Gaps = 19/112 (16%)
Frame = +1
Query: 475 VHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKA--LRADENYYK-AQTH 531
+H V+ G+ Y+ + DL VLL T K +DFGLSK +E ++K A+
Sbjct: 22 IHLVT-GLHYIHSLGILFHDLRPSKVLLDTSGVLKFADFGLSKVEGENLEELFFKFAEAG 198
Query: 532 GKWPVK----------------WYAPECINYYKFSSKSDVWSFGVLMWEAFS 567
+W ++ + APE + S SD+W+ G + +E FS
Sbjct: 199 DQWNIQSAEEMMKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFS 354
>10546
Length = 790
Score = 40.8 bits (94), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 27/86 (31%), Positives = 44/86 (51%), Gaps = 6/86 (6%)
Frame = +2
Query: 165 KMPWFHGKISREESEQIVLIGSKTNGKFLIRARDNNGS--YALCLLHEGKVLHYRIDKDK 222
K W+HG I R + E +V K +G FL+R D + Y L + H+G V + RI
Sbjct: 317 KYEWYHGHIERSKGENLVKHVGK-DGTFLVRVSDKDPKFPYTLVVYHKGSVNNLRIRLRP 493
Query: 223 TGKLSIPEGKK----FDTLWQLVEHY 244
K+++ + KK F + ++EH+
Sbjct: 494 DDKVALGDEKKGEIAFQDVAAMIEHH 571
>30231
Length = 340
Score = 39.7 bits (91), Expect = 0.003, Method: Composition-based stats.
Identities = 30/78 (38%), Positives = 43/78 (55%), Gaps = 8/78 (10%)
Frame = -2
Query: 189 NGKFLIRARDN-NGSYALCLLHEGKVLHYRIDKDKTGKLSI-PEGK----KFDTLWQLVE 242
+G FL+R ++ + +Y LCLL + +V YRI DK G+LS+ EG F L L++
Sbjct: 252 DGSFLVRDSESVSNAYVLCLLFQLRVHQYRILPDKDGRLSVQSEGDMQPLSFIDLPSLIQ 73
Query: 243 HYSYKAD--GLLRVLTVP 258
Y K D GL+ L P
Sbjct: 72 VYISKGDKNGLICPLRRP 19
>13840
Length = 446
Score = 38.9 bits (89), Expect = 0.007, Method: Compositional matrix adjust.
Identities = 36/128 (28%), Positives = 67/128 (52%), Gaps = 8/128 (6%)
Frame = -1
Query: 376 ELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRM 435
E+G GN+GTV K +++ V +AVK +++ + K L+ VM+ + P+IV+
Sbjct: 374 EIGRGNYGTVNKMRHKITSTV--MAVKRIRSTVEEREQKQLLMDLDVVMRSNNCPFIVQF 201
Query: 436 IGIC--EAESWMLVMEMAELGPLNKYLQ----QNRHVKDKNIIELVHQVSM-GMKYL-EE 487
G E + W + ME+ E L+K+ + + + +NI+ + ++ + YL EE
Sbjct: 200 YGALFKEGDCW-ICMELME-TSLDKFYKFVYGEMQSSIPENILGKITVATLKALNYLKEE 27
Query: 488 SNFVHRDL 495
+HRD+
Sbjct: 26 LRIIHRDV 3
>21433
Length = 590
Score = 38.1 bits (87), Expect = 0.012, Method: Composition-based stats.
Identities = 28/98 (28%), Positives = 44/98 (44%)
Frame = +2
Query: 475 VHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKW 534
++Q+S ++Y +HRD+ N+LL + KI+DFG S + T
Sbjct: 185 IYQLSSALEYCHYRKVIHRDIKPENLLLGLKGDLKIADFGWSVHAPSSRRTTMCGT---- 352
Query: 535 PVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKP 572
+ + PE + D+WS GVL +E F G P
Sbjct: 353 -LDYLPPEMVEGKTHDENVDLWSLGVLCYE-FLVGTPP 460
>04627
Length = 572
Score = 37.7 bits (86), Expect = 0.014, Method: Compositional matrix adjust.
Identities = 21/56 (37%), Positives = 30/56 (53%), Gaps = 2/56 (3%)
Frame = +3
Query: 165 KMPWFHGKISREESEQIVLIGSKTNGKFLIRARDNNGS--YALCLLHEGKVLHYRI 218
K W+HG I R + E +V K +G FL+R D + Y L + H+G V + RI
Sbjct: 348 KYEWYHGHIERSKGENLVKHVGK-DGTFLVRVSDKDPKFPYTLVVYHKGSVNNLRI 512
>35671
Length = 567
Score = 37.7 bits (86), Expect = 0.015, Method: Compositional matrix adjust.
Identities = 17/45 (37%), Positives = 22/45 (48%)
Frame = -3
Query: 586 EKGERMGCPAGCPREMYDLMNLCWTYDVENRPGFAAVELRLRNYY 630
+KG R+ P C E Y +M CWT E RP F + + N Y
Sbjct: 565 QKGNRLAKPISCTDEAYKVMLQCWTESREERPTFKKLVPVMENLY 431
>00394
Length = 548
Score = 37.0 bits (84), Expect = 0.024, Method: Compositional matrix adjust.
Identities = 32/103 (31%), Positives = 50/103 (48%), Gaps = 6/103 (5%)
Frame = -2
Query: 366 DRKLLTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQ 425
D + L DKE+G G+F TV KG V VA L+++ + A + EA +++
Sbjct: 304 DNRFLKF-DKEIGRGSFKTVYKGLDTELGV--AVAWCELQDKKWNKAERQRFKEEAEMLK 134
Query: 426 QLDNPYIVRMIGICEAES------WMLVMEMAELGPLNKYLQQ 462
+L +P IVR E + +LV E+ G L YL++
Sbjct: 133 ELQHPNIVRFFDYWEEHNHRNRKVIILVTELMTSGTLKTYLKR 5
>18881
Length = 762
Score = 36.2 bits (82), Expect = 0.040, Method: Compositional matrix adjust.
Identities = 19/58 (32%), Positives = 32/58 (55%), Gaps = 2/58 (3%)
Frame = -3
Query: 189 NGKFLIRARDNNGSYALCLLH--EGKVLHYRIDKDKTGKLSIPEGKKFDTLWQLVEHY 244
+G FLIR N + C + V H +++++ G+ + +G FD++ QLVEHY
Sbjct: 745 DGTFLIRVT-NTSARESCPQY*YANAVRHIKVNRNPQGRFYLADGHYFDSVQQLVEHY 575
>18481
Length = 437
Score = 35.8 bits (81), Expect = 0.047, Method: Composition-based stats.
Identities = 44/129 (34%), Positives = 65/129 (50%), Gaps = 8/129 (6%)
Frame = -1
Query: 397 KTVAVKILKNEANDPALKDELLA-EANVMQQLD-NPYIVRMIGI-CEAESWMLVMEMAEL 453
K +AVKI EA D +K +LL EA V +Q+ +P + M E LVME+ L
Sbjct: 407 KDIAVKI---EAID--VKHQLLHYEAKVYEQIGRHPGLPTMYHYGTEKHFNALVMEL--L 249
Query: 454 GPLNK--YLQQNRHVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQ---HYA 508
GP + ++ R K I+ + Q+ ++++ + F+HRDL N L+ H
Sbjct: 248 GPSLEELFVICKRRFTLKTILMVSDQLLSRLEFIHQKCFIHRDLKPDNFLMGLGRHCHRL 69
Query: 509 KISDFGLSK 517
I DFGLSK
Sbjct: 68 YIIDFGLSK 42
>31489
Length = 329
Score = 35.4 bits (80), Expect = 0.064, Method: Composition-based stats.
Identities = 14/46 (30%), Positives = 30/46 (65%)
Frame = +3
Query: 456 LNKYLQQNRHVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVL 501
L++ + ++ + +++I ++Q+ G+KY+ +N VHRDL N+L
Sbjct: 126 LHRIIYSDQPLTEEHIRYFLYQILRGLKYIHSANVVHRDLKPSNLL 263
>31789
Length = 676
Score = 35.0 bits (79), Expect = 0.10, Method: Compositional matrix adjust.
Identities = 40/151 (26%), Positives = 68/151 (45%), Gaps = 9/151 (5%)
Frame = +2
Query: 341 LPMDTEVYESPYADP-EEIRPKEVYL--DRKLLTLEDKELGSGNFGTVKKGYYQMKKVVK 397
L ++ E+ + A +EI K V D + L D E+G G+F TV KG V
Sbjct: 230 LQLEGEIKDIQQAQKVQEIEEKAVASSPDNRFLKF-DVEIGRGSFKTVYKGLDTELGVA- 403
Query: 398 TVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRMIGICEAES------WMLVMEMA 451
VA L+++ + + EA ++++L +P IVR E + +LV E+
Sbjct: 404 -VAWCELQDKKWNKTERQRFKEEAEMLKELQHPNIVRFFDYWEEHNHRNRKVIILVTELM 580
Query: 452 ELGPLNKYLQQNRHVKDKNIIELVHQVSMGM 482
G L YL++ + + K + Q+ G+
Sbjct: 581 TSGTLKTYLKRFKKINLKVLKNWCRQILKGL 673
>14257
Length = 919
Score = 33.9 bits (76), Expect = 0.20, Method: Compositional matrix adjust.
Identities = 23/83 (27%), Positives = 43/83 (51%), Gaps = 2/83 (2%)
Frame = -3
Query: 168 WFHGKISREESEQIVLIGSKTNGKFLIRARDNNGS-YALCLLHEGKVLH-YRIDKDKTGK 225
W+HGKI R+E+E+++ + +G FL+R N+ + + L G V H +D D +
Sbjct: 890 WYHGKIGRKEAEKLL----ELDGDFLVREASNSAAQFVLSGRQNGNVRHLLLVDPDGIVR 723
Query: 226 LSIPEGKKFDTLWQLVEHYSYKA 248
+ FD++ L+ ++ A
Sbjct: 722 ---TKDFIFDSVSHLINYHRQNA 663
>26009
Length = 886
Score = 33.9 bits (76), Expect = 0.23, Method: Compositional matrix adjust.
Identities = 11/51 (21%), Positives = 28/51 (54%)
Frame = +3
Query: 461 QQNRHVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKIS 511
++N+ + ++ Q+ + ++ VHRD+ NVL++T ++++S
Sbjct: 687 RRNKACGSREAKSVMKQLVSALDFMHSKQLVHRDIKPENVLILTPDFSRVS 839
>16708
Length = 1397
Score = 33.1 bits (74), Expect = 0.32, Method: Compositional matrix adjust.
Identities = 27/118 (22%), Positives = 52/118 (44%), Gaps = 11/118 (9%)
Frame = -1
Query: 446 LVMEMAELGPL-NKYLQQNRHVKDKN----------IIELVHQVSMGMKYLEESNFVHRD 494
+++ E+GPL N Y H K+K + + Q ++++ E VH D
Sbjct: 1184 ILLHFYEMGPLCNVY----AHYKNKEMPIRWSNPAMVCCIAGQXVCALEHIHELGVVHMD 1017
Query: 495 LAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINYYKFSSK 552
+ A NVL+ K++D+G+++ + Y A P + ++ C N F ++
Sbjct: 1016 VKADNVLVDAHGNCKLTDYGIAQLYKV----YPA------PTETHSSGCTNKRTFYTR 873
>38046
Length = 446
Score = 33.1 bits (74), Expect = 0.38, Method: Composition-based stats.
Identities = 11/25 (44%), Positives = 19/25 (76%)
Frame = -1
Query: 478 VSMGMKYLEESNFVHRDLAARNVLL 502
++ M Y+E+ NF+HR+L RN+L+
Sbjct: 98 IADAMAYMEKENFIHRNLGDRNILV 24
>21210
Length = 518
Score = 32.3 bits (72), Expect = 0.53, Method: Compositional matrix adjust.
Identities = 25/91 (27%), Positives = 42/91 (46%), Gaps = 9/91 (9%)
Frame = +3
Query: 538 WYAPECIN----YYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGC 593
+ APE I+ + + +SDVWS G+ + E + G+ PYR K + L++ R
Sbjct: 18 YMAPERIDPRASSHGYDVRSDVWSLGITLME-LATGRFPYR--KWVSIFDQLQQVVRGVA 188
Query: 594 PA-----GCPREMYDLMNLCWTYDVENRPGF 619
P + + +N C T D + RP +
Sbjct: 189 PCLPHDGAFSHDFVNFVNKCLTKDEKQRPKY 281
>36481
Length = 806
Score = 32.3 bits (72), Expect = 0.54, Method: Compositional matrix adjust.
Identities = 38/152 (25%), Positives = 67/152 (44%), Gaps = 19/152 (12%)
Frame = +2
Query: 378 GSGNFGTVKKGYYQMKKVVK--TVAVKILKNEANDPALKDELLAEANVMQQL--DNPY-- 431
G G FG V Q K ++K +A+KI+KN ++ E NV+++L +P+
Sbjct: 389 GEGTFGKV----VQCKDLLKGDDIALKIIKNV---DKYREAAKLEINVLEKLREKDPHAK 547
Query: 432 --IVRMIG-------ICEAESWMLVMEMAELGPLNKY----LQQNRHVKDKNIIELVHQV 478
V+M+ +C + ML + + + N Y ++Q RH+ +Q+
Sbjct: 548 HMCVQMLDWFDYHGHVCISFH-MLGLSVFDFLKDNSYGAYPIEQVRHIS--------YQL 700
Query: 479 SMGMKYLEESNFVHRDLAARNVLLVTQHYAKI 510
+ +L E+ H DL N+L V Y +
Sbjct: 701 CYAVNFLHENQLTHTDLKPENILFVDSQYENV 796
>15741
Length = 402
Score = 32.3 bits (72), Expect = 0.58, Method: Composition-based stats.
Identities = 13/33 (39%), Positives = 20/33 (60%)
Frame = -3
Query: 469 KNIIELVHQVSMGMKYLEESNFVHRDLAARNVL 501
++ V+ GM ++ + VHRD+AARNVL
Sbjct: 100 RDFFSFALHVARGMAHVANNKIVHRDVAARNVL 2
>18401
Length = 463
Score = 32.0 bits (71), Expect = 0.75, Method: Compositional matrix adjust.
Identities = 17/48 (35%), Positives = 26/48 (54%)
Frame = -3
Query: 540 APECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEK 587
APE I +S DVWS G +M+E ++ G ++ E AM+E+
Sbjct: 428 APEVILELGWSHPCDVWSVGCIMFELYT-GYTLFQTHDNKEHLAMMER 288
>00191
Length = 1400
Score = 31.6 bits (70), Expect = 1.1, Method: Compositional matrix adjust.
Identities = 16/39 (41%), Positives = 21/39 (53%)
Frame = -1
Query: 369 LLTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKNE 407
L L D LG NF K G+ +KKV+KT+ KN+
Sbjct: 1130 LXCLADPCLGVRNFRDTKSGFPPLKKVMKTITKPYXKNK 1014
>29590
Length = 320
Score = 31.2 bits (69), Expect = 1.4, Method: Composition-based stats.
Identities = 14/46 (30%), Positives = 26/46 (56%)
Frame = +3
Query: 538 WYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTA 583
+ APE ++Y S ++D+WS GVL + + P+ G+ + +A
Sbjct: 72 YVAPEVLDYEPLSIQTDMWSLGVLSYVMLT-ACSPFVGITSKKHSA 206
>25019
Length = 730
Score = 30.8 bits (68), Expect = 1.8, Method: Compositional matrix adjust.
Identities = 20/68 (29%), Positives = 28/68 (41%), Gaps = 4/68 (5%)
Frame = +3
Query: 496 AARNVLLVTQHYAKISDFGLSK----ALRADENYYKAQTHGKWPVKWYAPECINYYKFSS 551
AA NVLL + K++DFGL K R + +++ APE +
Sbjct: 255 AAENVLLDKDGHVKLTDFGLCKEAITGTRVTHTFCGT-------IEYMAPEILTRTGHGK 413
Query: 552 KSDVWSFG 559
D WS G
Sbjct: 414 AVDWWSLG 437
>02638
Length = 1490
Score = 30.4 bits (67), Expect = 2.1, Method: Compositional matrix adjust.
Identities = 26/97 (26%), Positives = 39/97 (40%), Gaps = 4/97 (4%)
Frame = +1
Query: 526 YKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAML 585
++ Q G + + APE + + DVWS G +M E + + P+ S A++
Sbjct: 4 FQGQLLGT--IAFMAPEVLRGESYGRACDVWSVGCVMIEMCTC-RPPWNSHDISNHLALI 174
Query: 586 EKGERMGCPAGCPREMY----DLMNLCWTYDVENRPG 618
K P P M DLM C D + RP
Sbjct: 175 FKIASSVDPPPIPENMSPPVRDLMLRCLEQDSDFRPS 285
>37602
Length = 804
Score = 30.0 bits (66), Expect = 2.7, Method: Compositional matrix adjust.
Identities = 17/72 (23%), Positives = 30/72 (41%)
Frame = -1
Query: 442 ESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVL 501
E + ME G + + + I + + G+ YL +HRD+ N+L
Sbjct: 300 EKLWIAMEYCGGGSMQDIYHVTGPLTEPQIAFVCRETLKGLHYLHRRGKMHRDIKGANIL 121
Query: 502 LVTQHYAKISDF 513
L + K++DF
Sbjct: 120 LTEEGDVKLADF 85
>07933
Length = 728
Score = 29.6 bits (65), Expect = 4.0, Method: Compositional matrix adjust.
Identities = 11/30 (36%), Positives = 17/30 (56%)
Frame = +3
Query: 594 PAGCPREMYDLMNLCWTYDVENRPGFAAVE 623
P CP +Y++M CW+ + RP F +E
Sbjct: 3 PNYCPNLLYNIMMQCWSAEPSARPTFHKLE 92
>14799
Length = 565
Score = 29.6 bits (65), Expect = 4.4, Method: Composition-based stats.
Identities = 17/43 (39%), Positives = 21/43 (48%)
Frame = -3
Query: 369 LLTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDP 411
L L D LG NF K G+ +KKV+KT+ K N P
Sbjct: 302 LRCLADPCLGVRNFRDTKSGFPPLKKVMKTITKPYNKKXKNRP 174
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000378529 | hsapiens_gene_ensembl | Fizzy-related
protein homolog (Fzr) (Cdh1/Hct1 homolog) (hCDH1) (CDC20-like protein
1). [Source:Uniprot/SWISSPROT;Acc:Q9UM11]
(496 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
14500 156 2e-50
34005 124 2e-31
29912 132 3e-31
14884 70 2e-12
00561 58 2e-11
02147 60 3e-09
27760 59 4e-09
01327 57 2e-08
13335 57 2e-08
30256 56 3e-08
17598 55 6e-08
19498 55 6e-08
03156 54 1e-07
27465 51 1e-06
12806 51 1e-06
03387 50 2e-06
19949 50 3e-06
17266 49 5e-06
16105 48 9e-06
01598 45 6e-05
12574 45 7e-05
16389 45 8e-05
02960 45 1e-04
01805 44 2e-04
01249 43 2e-04
15780 42 7e-04
30295 40 0.002
14555 40 0.003
18981 38 0.007
10264 38 0.009
01768 37 0.018
27475 37 0.019
19863 37 0.022
31474 37 0.023
02090 36 0.034
13278 36 0.038
01462 36 0.045
26107 36 0.045
37142 35 0.071
31054 35 0.084
21921 34 0.12
12140 34 0.13
34511 33 0.23
19140 33 0.29
15337 33 0.34
21105 33 0.36
15972 33 0.37
01584 33 0.38
21025 32 0.48
15118 32 0.50
36111 32 0.77
27270 31 0.94
10162 31 1.0
11493 31 1.1
27681 31 1.4
07665 30 1.6
28289 30 2.6
17807 30 2.9
12841 29 5.4
16199 29 5.4
30679 28 5.9
00105 28 6.2
38177 28 7.1
17602 28 7.1
30297 28 7.8
30108 28 9.1
>14500
Length = 1238
Score = 156 bits (394), Expect(2) = 2e-50, Method: Compositional matrix adjust.
Identities = 69/118 (58%), Positives = 89/118 (75%)
Frame = +3
Query: 363 WSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNLAWSKHANELVSTHGYSQ 422
W P Q LLASGGGTADR I FWN TG L +DT SQVC L WSK EL+S+HG++Q
Sbjct: 225 WCPWQPSLLASGGGTADRHIHFWNCNTGTNLSSVDTKSQVCALLWSKEHRELISSHGFAQ 404
Query: 423 NQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKTRSTK 480
NQ+++WKYP++++VA+LTGH+ RVL++AMSPDGE +V+ A DETLR W F+ + K
Sbjct: 405 NQLIIWKYPAMSRVAELTGHTARVLHMAMSPDGETVVSAAADETLRLWKCFTVDKEKK 578
Score = 61.2 bits (147), Expect(2) = 2e-50, Method: Compositional matrix adjust.
Identities = 31/59 (52%), Positives = 39/59 (66%), Gaps = 5/59 (8%)
Frame = +2
Query: 309 LQGHRQEVCGLKWSTDHQLLASGGNDNKLLVW-----NHSSLSPVQQYTEHLAAVKAIA 362
L GH QEVCGL+WS D + LASG NDN L VW +S P+ +++H AAVKA+A
Sbjct: 47 LSGHSQEVCGLRWSPDGKYLASGANDNLLCVWPAQVTGGNSTQPLHTFSQHQAAVKALA 223
Score = 47.0 bits (110), Expect(2) = 2e-06, Method: Compositional matrix adjust.
Identities = 26/79 (32%), Positives = 43/79 (54%), Gaps = 2/79 (2%)
Frame = +3
Query: 313 RQEVCGLKWSTDHQLLAS--GGNDNKLLVWNHSSLSPVQQYTEHLAAVKAIAWSPHQHGL 370
+ +VC L WS +H+ L S G N+L++W + ++S V + T H A V +A SP +
Sbjct: 333 KSQVCALLWSKEHRELISSHGFAQNQLIIWKYPAMSRVAELTGHTARVLHMAMSPDGETV 512
Query: 371 LASGGGTADRCIRFWNTLT 389
+++ AD +R W T
Sbjct: 513 VSAA---ADETLRLWKCFT 560
Score = 22.7 bits (47), Expect(2) = 2e-06, Method: Compositional matrix adjust.
Identities = 17/59 (28%), Positives = 24/59 (40%), Gaps = 5/59 (8%)
Frame = +2
Query: 225 LSVEGDSVTSVGWSERGNLVAVGTHKGFVQIWDAA-----AGKKLSMLEGHTARVGALA 278
LS V + WS G +A G + + +W A + + L H A V ALA
Sbjct: 47 LSGHSQEVCGLRWSPDGKYLASGANDNLLCVWPAQVTGGNSTQPLHTFSQHQAAVKALA 223
Score = 33.9 bits (76), Expect = 0.16, Method: Compositional matrix adjust.
Identities = 16/36 (44%), Positives = 20/36 (55%)
Frame = +2
Query: 435 QVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFW 470
V L+GHS V L SPDG+ + +GA D L W
Sbjct: 35 HVGTLSGHSQEVCGLRWSPDGKYLASGANDNLLCVW 142
>34005
Length = 456
Score = 124 bits (311), Expect(2) = 2e-31, Method: Compositional matrix adjust.
Identities = 62/114 (54%), Positives = 76/114 (66%), Gaps = 3/114 (2%)
Frame = +1
Query: 314 QEVCGLKWSTDHQLLASGGNDNKLLVWNHS---SLSPVQQYTEHLAAVKAIAWSPHQHGL 370
QEVCGL WS D LASG NDN + +W+ + + P+ T H AAVKA+AW P Q +
Sbjct: 115 QEVCGLSWSPDATFLASGSNDNSVNIWDSTLGMDVPPLHTLTSHQAAVKAVAWCPWQTRM 294
Query: 371 LASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNLAWSKHANELVSTHGYSQNQ 424
LA+GGGT DR IRFWNT TG ++ +DT SQVC++ W K ELVS HGY NQ
Sbjct: 295 LATGGGTNDRHIRFWNTNTGACVKAVDTQSQVCSVLWCKEHRELVSGHGYVMNQ 456
Score = 30.0 bits (66), Expect(2) = 2e-31, Method: Compositional matrix adjust.
Identities = 13/25 (52%), Positives = 15/25 (60%)
Frame = +3
Query: 276 ALAWNAEQLSSGSRDRMILQRDIRT 300
LAWN+ LSSGSR I D+R
Sbjct: 3 CLAWNSHILSSGSRSGNIHHHDVRV 77
Score = 40.8 bits (94), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 38/133 (28%), Positives = 51/133 (38%), Gaps = 8/133 (6%)
Frame = +1
Query: 207 TCVYLWSACTSQVTRLCDLSVEGDSVTSVGWSERGNLVAVGTHKGFVQIWDAAAGKK--- 263
T Y W A TR + V + WS +A G++ V IWD+ G
Sbjct: 61 TTTYAWRA-----TRWGFCPLTPQEVCGLSWSPDATFLASGSNDNSVNIWDSTLGMDVPP 225
Query: 264 LSMLEGHTARVGALAWNAEQ-----LSSGSRDRMILQRDIRTPPLQSERRLQGHRQEVCG 318
L L H A V A+AW Q G+ DR I + T Q +VC
Sbjct: 226 LHTLTSHQAAVKAVAWCPWQTRMLATGGGTNDRHIRFWNTNTGACVKAVDTQ---SQVCS 396
Query: 319 LKWSTDHQLLASG 331
+ W +H+ L SG
Sbjct: 397 VLWCKEHRELVSG 435
Score = 34.3 bits (77), Expect = 0.12, Method: Compositional matrix adjust.
Identities = 27/84 (32%), Positives = 37/84 (44%), Gaps = 6/84 (7%)
Frame = +1
Query: 395 CIDTGSQVCNLAWSKHANELVSTHGYSQNQILVWKYP---SLTQVAKLTGHSYRVLYLAM 451
C T +VC L+WS A L S G + N + +W + + LT H V +A
Sbjct: 100 CPLTPQEVCGLSWSPDATFLAS--GSNDNSVNIWDSTLGMDVPPLHTLTSHQAAVKAVAW 273
Query: 452 SP-DGEAIVTGAG--DETLRFWNV 472
P + TG G D +RFWN
Sbjct: 274 CPWQTRMLATGGGTNDRHIRFWNT 345
>29912
Length = 510
Score = 132 bits (332), Expect = 3e-31, Method: Compositional matrix adjust.
Identities = 72/152 (47%), Positives = 93/152 (61%), Gaps = 5/152 (3%)
Frame = +3
Query: 230 DSVTSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNAEQLSSGSR 289
+ + +V W + GN +A+GT G VQ+WD KKL + GH ARVG+L+WN+ +SSGSR
Sbjct: 12 EYIGAVSWIKEGNYLALGTSTGEVQVWDVTQQKKLRTMAGHAARVGSLSWNSFIVSSGSR 191
Query: 290 DRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVW-----NHSS 344
I D+R L GH QEVCGL+WS D + LASG NDN L VW +S
Sbjct: 192 SGNIHHHDVRVAD-HHVGTLSGHSQEVCGLRWSPDGKYLASGANDNLLCVWPAQVTGGNS 368
Query: 345 LSPVQQYTEHLAAVKAIAWSPHQHGLLASGGG 376
P+ +++H AAVKA+AW P Q LASGGG
Sbjct: 369 TQPLHTFSQHQAAVKALAWCPWQPSXLASGGG 464
Score = 34.3 bits (77), Expect = 0.12, Method: Compositional matrix adjust.
Identities = 16/36 (44%), Positives = 20/36 (55%)
Frame = +3
Query: 435 QVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFW 470
V L+GHS V L SPDG+ + +GA D L W
Sbjct: 234 HVGTLSGHSQEVCGLRWSPDGKYLASGANDNLLCVW 341
Score = 28.9 bits (63), Expect = 4.8, Method: Compositional matrix adjust.
Identities = 24/78 (30%), Positives = 34/78 (43%), Gaps = 8/78 (10%)
Frame = +3
Query: 225 LSVEGDSVTSVGWSERGNLVAVGTHKGFVQIWDAA-----AGKKLSMLEGHTARVGALAW 279
LS V + WS G +A G + + +W A + + L H A V ALAW
Sbjct: 246 LSGHSQEVCGLRWSPDGKYLASGANDNLLCVWPAQVTGGNSTQPLHTFSQHQAAVKALAW 425
Query: 280 NAEQ---LSSGSRDRMIL 294
Q L+SG D +I+
Sbjct: 426 CPWQPSXLASGGGDVLIV 479
>14884
Length = 632
Score = 70.1 bits (170), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 33/79 (41%), Positives = 49/79 (62%)
Frame = -1
Query: 169 RKISKIPFKVLDAPELQDDFYLNLVDWSSLNVLSVGLGTCVYLWSACTSQVTRLCDLSVE 228
R I P VLDAP + DD+YL+ +DWSS N ++ LG VYLW A + +T+L ++ +
Sbjct: 245 RHIPSRPEHVLDAPVVLDDYYLHTIDWSSTNTVAAALGPEVYLWHARDATITQLMRVA-D 69
Query: 229 GDSVTSVGWSERGNLVAVG 247
D ++SV W G ++ VG
Sbjct: 68 SDYISSVSWISDGTVLGVG 12
>00561
Length = 1003
Score = 57.8 bits (138), Expect(2) = 2e-11, Method: Compositional matrix adjust.
Identities = 54/203 (26%), Positives = 95/203 (46%), Gaps = 6/203 (2%)
Frame = -3
Query: 232 VTSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNAE--QLSSGSR 289
++ V S GN G+ +++WD AAGK EGHT V ++A++A+ Q+ SGSR
Sbjct: 857 ISDVVLSSDGNYALSGSWDQTLRLWDLAAGKTTRRFEGHTKDVLSVAFSADNRQIVSGSR 678
Query: 290 DRMILQRDIRTPPLQSERRLQ--GHRQEVCGLKWSTDHQ--LLASGGNDNKLLVWNHSSL 345
D+ I + + + +Q GH V +++S +H ++ S G D + VWN ++
Sbjct: 677 DKTIKLWNTLA---ECKFTIQEDGHTDWVSCVRFSPNHSNPIIVSCGWDRTVKVWNLANC 507
Query: 346 SPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNL 405
+ H + + SP G L + GG + + W+ G+ L ++ + L
Sbjct: 506 KLKNNHHGHNGYLNTVTVSP--DGSLCTSGGKDSKAL-LWDLNDGKNLYTLEHNDIINAL 336
Query: 406 AWSKHANELVSTHGYSQNQILVW 428
+S + L +G S I +W
Sbjct: 335 CFSPNRYWLCVAYGPS---IKIW 276
Score = 28.5 bits (62), Expect(2) = 2e-11, Method: Compositional matrix adjust.
Identities = 12/28 (42%), Positives = 16/28 (57%)
Frame = -2
Query: 445 RVLYLAMSPDGEAIVTGAGDETLRFWNV 472
+ L LA S DG+ + G D T+R W V
Sbjct: 201 QCLSLAWSTDGQTLFAGYSDNTIRVWQV 118
Score = 58.2 bits (139), Expect = 8e-09, Method: Compositional matrix adjust.
Identities = 46/200 (23%), Positives = 88/200 (44%), Gaps = 7/200 (3%)
Frame = -3
Query: 280 NAEQLSSGSRDRMI----LQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDN 335
+ + + S SRD+ + L RD T ++RL GH + + S+D SG D
Sbjct: 977 DPDTIISASRDKTLIVWKLTRDEDTNYGYPQKRLYGHSHFISDVVLSSDGNYALSGSWDQ 798
Query: 336 KLLVWNHSSLSPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQC 395
L +W+ ++ +++ H V ++A+S +++ G+ D+ I+ WNTL
Sbjct: 797 TLRLWDLAAGKTTRRFEGHTKDVLSVAFSADNRQIVS---GSRDKTIKLWNTLAECKFTI 627
Query: 396 IDTGSQ---VCNLAWSKHANELVSTHGYSQNQILVWKYPSLTQVAKLTGHSYRVLYLAMS 452
+ G C H+N ++ + G+ + + VW + GH+ + + +S
Sbjct: 626 QEDGHTDWVSCVRFSPNHSNPIIVSCGWDRT-VKVWNLANCKLKNNHHGHNGYLNTVTVS 450
Query: 453 PDGEAIVTGAGDETLRFWNV 472
PDG +G D W++
Sbjct: 449 PDGSLCTSGGKDSKALLWDL 390
Score = 38.1 bits (87), Expect = 0.007, Method: Compositional matrix adjust.
Identities = 19/60 (31%), Positives = 33/60 (55%), Gaps = 1/60 (1%)
Frame = -3
Query: 421 SQNQIL-VWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKTRST 479
S +Q L +W + + GH+ VL +A S D IV+G+ D+T++ WN ++ + T
Sbjct: 809 SWDQTLRLWDLAAGKTTRRFEGHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTLAECKFT 630
Score = 34.7 bits (78), Expect = 0.090, Method: Compositional matrix adjust.
Identities = 15/54 (27%), Positives = 33/54 (61%)
Frame = -3
Query: 438 KLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKTRSTKVKWESVSVLNL 491
+L GHS+ + + +S DG ++G+ D+TLR W++ + + + + + VL++
Sbjct: 881 RLYGHSHFISDVVLSSDGNYALSGSWDQTLRLWDLAAGKTTRRFEGHTKDVLSV 720
Score = 29.3 bits (64), Expect = 3.7, Method: Compositional matrix adjust.
Identities = 13/34 (38%), Positives = 19/34 (55%)
Frame = -2
Query: 310 QGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHS 343
+ + + L WSTD Q L +G +DN + VW S
Sbjct: 216 KAEQPQCLSLAWSTDGQTLFAGYSDNTIRVWQVS 115
>02147
Length = 1547
Score = 59.7 bits (143), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 49/230 (21%), Positives = 98/230 (42%), Gaps = 1/230 (0%)
Frame = +2
Query: 244 VAVGTHKGFVQIWDAAAGKKLSML-EGHTARVGALAWNAEQLSSGSRDRMILQRDIRTPP 302
A G +IWDA G++L H + + + L +GS ++++ D+
Sbjct: 218 AATGAADFSAKIWDAEKGEELQTFSHKHIVKSVDFSHDGTALLTGSNEKLLKVFDLVNTD 397
Query: 303 LQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKAIA 362
+ + GH + G + +D + + S +D + +W+ + VQQ T ++
Sbjct: 398 AEP-KSFAGHTSNIKGALFLSDGKRIISASDDKTVRLWSLETCQEVQQLTFDTPPT-SLT 571
Query: 363 WSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNLAWSKHANELVSTHGYSQ 422
SP ++ ++ T + I F+ T + ++ + + + + S H +E G
Sbjct: 572 LSPDKNTIIV----THSQNIAFYQADTLREMKKFEAEAPISSA--SLHQSERFFVAGGED 733
Query: 423 NQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNV 472
++ + Y + ++ GH V + SPDGE +G+ D TLR W
Sbjct: 734 FKMYKFDYETGKEIESFKGHFGPVHCVRFSPDGELYASGSEDGTLRLWQT 883
>27760
Length = 525
Score = 58.9 bits (141), Expect = 4e-09, Method: Compositional matrix adjust.
Identities = 31/35 (88%), Positives = 31/35 (88%)
Frame = -2
Query: 462 AGDETLRFWNVFSKTRSTKVKWESVSVLNLFTRIR 496
AGDETLRFWNVFSKTRSTK ES SVLNLFTRIR
Sbjct: 524 AGDETLRFWNVFSKTRSTK---ESKSVLNLFTRIR 429
>01327
Length = 2215
Score = 57.0 bits (136), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 58/257 (22%), Positives = 111/257 (43%), Gaps = 10/257 (3%)
Frame = +3
Query: 243 LVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNA--EQLSSGSRDRMILQRDIRT 300
L G+ V ++D G+ GH + + + A + S SRD+ I + +
Sbjct: 81 LCLSGSKDKSVVLYDYQNGRLEDRWTGHDREITKVCYGASCNGMFSASRDKTI--KMWQR 254
Query: 301 PPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKA 360
S R GH V + +TD+ LL SG DN + +W+ + + ++Q V
Sbjct: 255 GNSHSIRDFIGHDMVVTAIHLNTDNTLLCSGSRDNTVRIWDVETGACLRQNNIPQNLVTD 434
Query: 361 IAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNLAWSKHANE---LVST 417
+ W P H ++ +G D+ +R +++ T ++ T Q ++ A+ L +
Sbjct: 435 VKWLPGSHLIIQAG---EDKEVRIYDSRTLGIVRSF-TKKQYIQMSCDVTADGQFCLTCS 602
Query: 418 HGYSQN--QILVWKYPSLTQVAKLTGHSYRV---LYLAMSPDGEAIVTGAGDETLRFWNV 472
+G+ N + +W+ + + GH + L+L + D I T + D ++R WN+
Sbjct: 603 NGFGGNGCEATLWQLSDGSIQNEFKGHREAIEACLFLPSNQDMTLIATASRDCSVRVWNM 782
Query: 473 FSKTRSTKVKWESVSVL 489
F+K + +E L
Sbjct: 783 FTKECVCEQNFEGTGPL 833
>13335
Length = 863
Score = 57.0 bits (136), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 52/203 (25%), Positives = 90/203 (44%), Gaps = 24/203 (11%)
Frame = +1
Query: 293 ILQRDIRTPPLQSERRLQGHRQ-EVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQY 351
++ D++T ++ E + VC S+ H L SG +D+ + +W ++ V+ Y
Sbjct: 4 VIVWDVKTGSIKGEYQHASKSSIRVCKFSPSSSH--LVSGSDDDTICMWEVATQKLVRSY 177
Query: 352 TEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQP------LQCIDTGSQVCNL 405
H +V A+A+SP+ H L SG D + W+ G + D G C
Sbjct: 178 VGHEDSVMALAYSPNGH-YLVSGSPNGD--LYVWDASFGHCRHLTLRVDAHDLGVTCCEF 348
Query: 406 A---------WSKHANELVSTHGYSQNQILVWKY------PSLTQVAK--LTGHSYRVLY 448
+ S N L++T G N I +W + P +T + L+GHS V+
Sbjct: 349 SPTFGTACAENSSTCNLLLATGG-KDNLIKLWTFSAQVGSPEVTLQCRDILSGHSDLVMA 525
Query: 449 LAMSPDGEAIVTGAGDETLRFWN 471
A SP + +G+ D+++R W+
Sbjct: 526 CAFSPSSALLASGSFDKSVRLWD 594
Score = 44.7 bits (104), Expect = 8e-05, Method: Compositional matrix adjust.
Identities = 55/205 (26%), Positives = 91/205 (44%), Gaps = 28/205 (13%)
Frame = +1
Query: 209 VYLWSACTSQVTRLCDLSVEG--DSVTSVGWSERGNLVAVGTHKGFVQIWDAAAG--KKL 264
+ +W T ++ R S G DSV ++ +S G+ + G+ G + +WDA+ G + L
Sbjct: 133 ICMWEVATQKLVR----SYVGHEDSVMALAYSPNGHYLVSGSPNGDLYVWDASFGHCRHL 300
Query: 265 SM-LEGHTARVGALAWN-------AEQ-------LSSGSRDRMI----LQRDIRTP--PL 303
++ ++ H V ++ AE L++G +D +I + +P L
Sbjct: 301 TLRVDAHDLGVTCCEFSPTFGTACAENSSTCNLLLATGGKDNLIKLWTFSAQVGSPEVTL 480
Query: 304 QSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYT---EHLAAVKA 360
Q L GH V +S LLASG D + +W+ S+ V ++ H V
Sbjct: 481 QCRDILSGHSDLVMACAFSPSSALLASGSFDKSVRLWD--SVKGVALFSIEACHSRFVTC 654
Query: 361 IAWSPHQHGLLASGGGTADRCIRFW 385
A+S LLAS G+ DR I+ W
Sbjct: 655 CAFSI-DGTLLAS--GSMDRIIKIW 720
Score = 44.7 bits (104), Expect = 8e-05, Method: Compositional matrix adjust.
Identities = 61/220 (27%), Positives = 89/220 (40%), Gaps = 25/220 (11%)
Frame = +1
Query: 247 GTHKGFVQIWDAAAGKKLSMLEGHTARVGALAW--NAEQLSSGSRDRMILQRDIRTPPLQ 304
G+ + +W+ A K + GH V ALA+ N L SGS + + D +
Sbjct: 115 GSDDDTICMWEVATQKLVRSYVGHEDSVMALAYSPNGHYLVSGSPNGDLYVWDASFGHCR 294
Query: 305 S-ERRLQGHRQEV------------CGLKWSTDHQLLASGGNDNKLLVWNHS-------- 343
R+ H V C ST + LLA+GG DN + +W S
Sbjct: 295 HLTLRVDAHDLGVTCCEFSPTFGTACAENSSTCNLLLATGGKDNLIKLWTFSAQVGSPEV 474
Query: 344 SLSPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQ-- 401
+L + H V A A+SP LLAS G+ D+ +R W+++ G L I+
Sbjct: 475 TLQCRDILSGHSDLVMACAFSP-SSALLAS--GSFDKSVRLWDSVKGVALFSIEACHSRF 645
Query: 402 VCNLAWSKHANELVSTHGYSQNQILVWKYPSLTQVAKLTG 441
V A+S L S G I +WK LT + + G
Sbjct: 646 VTCCAFSIDGTLLAS--GSMDRIIKIWK---LTDTSSIMG 750
Score = 32.3 bits (72), Expect = 0.48, Method: Compositional matrix adjust.
Identities = 31/118 (26%), Positives = 53/118 (44%), Gaps = 11/118 (9%)
Frame = +1
Query: 243 LVAVGTHKGFVQIWDAAAG--------KKLSMLEGHTARVGALAWN--AEQLSSGSRDRM 292
L+A G +++W +A + +L GH+ V A A++ + L+SGS D+
Sbjct: 400 LLATGGKDNLIKLWTFSAQVGSPEVTLQCRDILSGHSDLVMACAFSPSSALLASGSFDKS 579
Query: 293 I-LQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQ 349
+ L ++ L S H + V +S D LLASG D + +W + S +
Sbjct: 580 VRLWDSVKGVALFSIEAC--HSRFVTCCAFSIDGTLLASGSMDRIIKIWKLTDTSSIM 747
>30256
Length = 961
Score = 56.2 bits (134), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 48/175 (27%), Positives = 78/175 (44%)
Frame = +3
Query: 220 TRLCDLSVEGDSVTSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAW 279
T +C ++ G S T S G V G+ +++WD +G L++L GH A V + +
Sbjct: 129 TGVCTHTLYGHSSTVRCLSLSGKKVVSGSRDATLRVWDIESGHCLNVLLGHMAAVRCVQY 308
Query: 280 NAEQLSSGSRDRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLV 339
+ +++ SG+ D + D T LQGH V L++ D + SG D + V
Sbjct: 309 DGKRVVSGAXDYTVRVWDPDTASCL--HTLQGHTNRVYSLQF--DGVYVVSGSLDTSIRV 476
Query: 340 WNHSSLSPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQ 394
W+ V H + + + LL S G AD ++ W+ TG+ LQ
Sbjct: 477 WDVRCGKLVHTLMGHQSLTSGLELKDN---LLVS--GNADSTVKVWDVHTGKCLQ 626
Score = 46.2 bits (108), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 55/217 (25%), Positives = 85/217 (39%)
Frame = +3
Query: 258 AAAGKKLSMLEGHTARVGALAWNAEQLSSGSRDRMILQRDIRTPPLQSERRLQGHRQEVC 317
A G+ + L GHT V + + SGS DR + + T L GH V
Sbjct: 3 AVTGRCIKNLIGHTGGVWSSQMTGNTVISGSTDRSLKVWNADTGV--CTHTLYGHSSTVR 176
Query: 318 GLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKAIAWSPHQHGLLASGGGT 377
L S + + SG D L VW+ S + H+AAV+ + + + + SG
Sbjct: 177 CLSLSG--KKVVSGSRDATLRVWDIESGHCLNVLLGHMAAVRCVQYDGKR---VVSGA-- 335
Query: 378 ADRCIRFWNTLTGQPLQCIDTGSQVCNLAWSKHANELVSTHGYSQNQILVWKYPSLTQVA 437
D +R W+ T C+ T N +S + + G I VW V
Sbjct: 336 XDYTVRVWDPDTA---SCLHTLQGHTNRVYSLQFDGVYVVSGSLDTSIRVWDVRCGKLVH 506
Query: 438 KLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFS 474
L GH + L + +V+G D T++ W+V +
Sbjct: 507 TLMGH--QSLTSGLELKDNLLVSGNADSTVKVWDVHT 611
>17598
Length = 875
Score = 55.1 bits (131), Expect = 6e-08, Method: Compositional matrix adjust.
Identities = 50/211 (23%), Positives = 92/211 (43%), Gaps = 11/211 (5%)
Frame = +1
Query: 282 EQLSSGSRDRMILQRDI--RTPPLQSE------RRLQGHRQEVCGLKWSTDHQLLASGGN 333
E L G RD++++ D+ R + E R LQGH V + S D + + S
Sbjct: 4 EFLIXGGRDKLLIVWDLVPRKDGDEDETWGGPRRTLQGHSHFVSDVSLSADSRYVLSSSW 183
Query: 334 DNKLLVWNHSSLSPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPL 393
D L +W+ + +++ H A+A+SP +ASGG D+ ++ WNT+ G+
Sbjct: 184 DATLRLWDIKKGNTTRRFISHTRDALAVAFSPDNRQ-IASGG--RDKALKIWNTV-GECK 351
Query: 394 QCIDTGSQ---VCNLAWSKHANELVSTHGYSQNQILVWKYPSLTQVAKLTGHSYRVLYLA 450
+D S V + + + A + I VW ++T GH ++ +
Sbjct: 352 FTVDANSHQDWVTCVKFHQDAKSPLVVSASMDKTIKVWDNQTMTLKHTFVGHKTQINAID 531
Query: 451 MSPDGEAIVTGAGDETLRFWNVFSKTRSTKV 481
++ + +G+ D + WN+ + T K+
Sbjct: 532 LALKTYYLASGSKDGIVMTWNIQNGTFLGKI 624
Score = 39.7 bits (91), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 45/212 (21%), Positives = 87/212 (41%), Gaps = 4/212 (1%)
Frame = +1
Query: 232 VTSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNAE--QLSSGSR 289
V+ V S V + +++WD G HT A+A++ + Q++SG R
Sbjct: 130 VSDVSLSADSRYVLSSSWDATLRLWDIKKGNTTRRFISHTRDALAVAFSPDNRQIASGGR 309
Query: 290 DRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQ--LLASGGNDNKLLVWNHSSLSP 347
D+ + + + H+ V +K+ D + L+ S D + VW++ +++
Sbjct: 310 DKALKIWNT-VGECKFTVDANSHQDWVTCVKFHQDAKSPLVVSASMDKTIKVWDNQTMTL 486
Query: 348 VQQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNLAW 407
+ H + AI + + L G+ D + WN G L ID +V + +
Sbjct: 487 KHTFVGHKTQINAIDLALKTYYL---ASGSKDGIVMTWNIQNGTFLGKIDCDCEVNAVKF 657
Query: 408 SKHANELVSTHGYSQNQILVWKYPSLTQVAKL 439
S + L G S+ I +W P+ ++ +
Sbjct: 658 SPNKYWLFV--GTSEG-IQIWDLPNQKKIKDI 744
>19498
Length = 903
Score = 55.1 bits (131), Expect = 6e-08, Method: Compositional matrix adjust.
Identities = 54/208 (25%), Positives = 77/208 (37%), Gaps = 8/208 (3%)
Frame = -1
Query: 222 LCDLSVEGDSVTSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNA 281
LC + V V WSE G +A G + IW + G G G+
Sbjct: 807 LCQMDSHLGCVNCVRWSENGKFLASGGDDKLIMIWQISRG------FGSGKSFGS----- 661
Query: 282 EQLSSGSRDRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWN 341
+ IL+ +S L+GH +V L WS LAS DN ++VWN
Sbjct: 660 --------NVTILEH------WRSVATLRGHAGDVLDLAWSPQDLWLASCSVDNTIVVWN 523
Query: 342 HSSLSP-VQQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGS 400
S V H VK + W P L + + D+ +R W T + C+ +
Sbjct: 522 ALKFSEQVAVIRGHAGMVKGVTWDPVGRYLASQ---SDDKTLRVWRTSDWKEETCVKSCF 352
Query: 401 QVCN-------LAWSKHANELVSTHGYS 421
+ C L WS N +VS H +
Sbjct: 351 KECGGTTHVLRLNWSPDGNHVVSAHAMN 268
Score = 43.5 bits (101), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 48/185 (25%), Positives = 72/185 (38%), Gaps = 34/185 (18%)
Frame = -1
Query: 332 GNDNKLLVWNHSSLSPVQ---------------QYTEHLAAVKAIAWSPHQHGLLASGGG 376
G+ K+++WN ++P++ Q HL V + WS + LASGG
Sbjct: 891 GDSGKVVIWN---MAPIRDEKEEADDDVPRVLCQMDSHLGCVNCVRWSENGK-FLASGGD 724
Query: 377 TADRCIRFWNTLTG--------------QPLQCIDT----GSQVCNLAWSKHANELVSTH 418
D+ I W G + + + T V +LAWS L S
Sbjct: 723 --DKLIMIWQISRGFGSGKSFGSNVTILEHWRSVATLRGHAGDVLDLAWSPQDLWLASCS 550
Query: 419 GYSQNQILVWKYPSLT-QVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKTR 477
N I+VW + QVA + GH+ V + P G + + + D+TLR W
Sbjct: 549 --VDNTIVVWNALKFSEQVAVIRGHAGMVKGVTWDPVGRYLASQSDDKTLRVWRTSDWKE 376
Query: 478 STKVK 482
T VK
Sbjct: 375 ETCVK 361
>03156
Length = 1014
Score = 54.3 bits (129), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 53/231 (22%), Positives = 102/231 (44%), Gaps = 10/231 (4%)
Frame = +1
Query: 269 GHTARVGALAWNA--EQLSSGSRDRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQ 326
GH + + + A + S SRD+ I + + S R GH V + +TD+
Sbjct: 49 GHDREITKVCYGASCNGMFSASRDKTI--KMWQRGNSHSIRDFIGHDMVVTAIHLNTDNT 222
Query: 327 LLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWN 386
LL SG DN + +W+ + + ++Q V + W P H ++ +G D+ +R ++
Sbjct: 223 LLCSGSRDNTVRIWDVETGACLRQNNIPQNLVTDVKWLPGSHLIIQAG---EDKEVRIYD 393
Query: 387 TLTGQPLQCIDTGSQVCNLAWSKHANE---LVSTHGYSQN--QILVWKYPSLTQVAKLTG 441
+ T ++ T Q ++ A+ L ++G+ N + +W+ + + G
Sbjct: 394 SRTLGIVRSF-TKKQYIQMSCDVTADGQFCLTCSNGFGGNGCEATLWQLSDGSIQNEFKG 570
Query: 442 HSYRV---LYLAMSPDGEAIVTGAGDETLRFWNVFSKTRSTKVKWESVSVL 489
H + L+L + D I T + D ++R WN+F+K + +E L
Sbjct: 571 HREAIEACLFLPSNQDMTLIATASRDCSVRVWNMFTKECVCEQNFEGTGPL 723
>27465
Length = 658
Score = 51.2 bits (121), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 30/113 (26%), Positives = 60/113 (53%), Gaps = 3/113 (2%)
Frame = -1
Query: 232 VTSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWN---AEQLSSGS 288
+T+V +++ G+ G++ +IWD A+ ++L LEGH V A+A+N +++ +GS
Sbjct: 352 LTNVAFNKSGSSFITGSYDRTCKIWDTASAEELHTLEGHRNVVYAIAFNNPFGDKVITGS 173
Query: 289 RDRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWN 341
D+ + T + L+GH E+ + ++ L+A+G D +W+
Sbjct: 172 FDKTC--KLWSTADGKCYHTLRGHTAEIVCVSFNPSSTLIATGSMDTTCRLWD 20
Score = 38.5 bits (88), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 24/98 (24%), Positives = 45/98 (45%), Gaps = 1/98 (1%)
Frame = -1
Query: 376 GTADRCIRFWNTLTGQPLQCIDTGSQVC-NLAWSKHANELVSTHGYSQNQILVWKYPSLT 434
G+ DR + W+T + + L ++ V +A++ + V T + + L W
Sbjct: 307 GSYDRTCKIWDTASAEELHTLEGHRNVVYAIAFNNPFGDKVITGSFDKTCKL-WSTADGK 131
Query: 435 QVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNV 472
L GH+ ++ ++ +P I TG+ D T R W+V
Sbjct: 130 CYHTLRGHTAEIVCVSFNPSSTLIATGSMDTTCRLWDV 17
>12806
Length = 961
Score = 50.8 bits (120), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 49/200 (24%), Positives = 81/200 (40%), Gaps = 11/200 (5%)
Frame = +3
Query: 284 LSSGSRDRMILQRDIRTPPLQSE--------RRLQGHRQEVCGLKWSTDHQLLASGGNDN 335
L SG RD I+ D+ E + L GH + L S D + S D
Sbjct: 54 LISGGRDNNIIVWDL*PKKDGDEDQTWGVPRKTLTGHSHFISDLALSADSRFALSSSWDA 233
Query: 336 KLLVWNHSSLSPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQC 395
L +W+ S ++ H V +A+SP +ASGG D+ ++ WN + G+
Sbjct: 234 TLRLWDIKKGSTTSRFINHTRDVLTVAFSPDNRQ-IASGG--RDKNLKIWNIM-GECKYT 401
Query: 396 IDTGSQ---VCNLAWSKHANELVSTHGYSQNQILVWKYPSLTQVAKLTGHSYRVLYLAMS 452
+D + V + + + + + I VW ++T GH ++ L MS
Sbjct: 402 VDANAHTDWVTCVRFHQDTKNPIVVSASNDKTIKVWDNHTMTLKNTFVGHKAQITALDMS 581
Query: 453 PDGEAIVTGAGDETLRFWNV 472
+ +V+G+ D WNV
Sbjct: 582 TN--YLVSGSKDGIAMTWNV 635
Score = 45.1 bits (105), Expect = 7e-05, Method: Compositional matrix adjust.
Identities = 44/192 (22%), Positives = 85/192 (44%), Gaps = 5/192 (2%)
Frame = +3
Query: 253 VQIWDAAAGKKLSMLEGHTARVGALAWNAE--QLSSGSRDRMILQRDIRTPPLQSERRLQ 310
+++WD G S HT V +A++ + Q++SG RD+ + +I +
Sbjct: 237 LRLWDIKKGSTTSRFINHTRDVLTVAFSPDNRQIASGGRDKNLKIWNI-MGECKYTVDAN 413
Query: 311 GHRQEVCGLKWSTDHQ--LLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKAIAWSPHQH 368
H V +++ D + ++ S ND + VW++ +++ + H A + A+ S +
Sbjct: 414 AHTDWVTCVRFHQDTKNPIVVSASNDKTIKVWDNHTMTLKNTFVGHKAQITALDMSTN-- 587
Query: 369 GLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNLAWSKHAN-ELVSTHGYSQNQILV 427
L S G+ D WN G + ID Q+ + ++ N + V +QN I +
Sbjct: 588 -YLVS--GSKDGIAMTWNVAEGSFVGKIDCDDQINAIKFNIENNKKKVWLFIGTQNGIQI 758
Query: 428 WKYPSLTQVAKL 439
W Y ++ +L
Sbjct: 759 WDYSGEKKIKEL 794
Score = 38.9 bits (89), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 15/53 (28%), Positives = 27/53 (50%)
Frame = +3
Query: 427 VWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKTRST 479
+W + ++ H+ VL +A SPD I +G D+ L+ WN+ + + T
Sbjct: 243 LWDIKKGSTTSRFINHTRDVLTVAFSPDNRQIASGGRDKNLKIWNIMGECKYT 401
Score = 35.0 bits (79), Expect = 0.063, Method: Compositional matrix adjust.
Identities = 25/77 (32%), Positives = 39/77 (50%), Gaps = 2/77 (2%)
Frame = +3
Query: 267 LEGHTARVGALAWNAEQ--LSSGSRDRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTD 324
L GH+ + LA +A+ S S D + DI+ S R H ++V + +S D
Sbjct: 153 LTGHSHFISDLALSADSRFALSSSWDATLRLWDIKKGSTTS--RFINHTRDVLTVAFSPD 326
Query: 325 HQLLASGGNDNKLLVWN 341
++ +ASGG D L +WN
Sbjct: 327 NRQIASGGRDKNLKIWN 377
Score = 29.3 bits (64), Expect = 4.3, Method: Compositional matrix adjust.
Identities = 18/73 (24%), Positives = 35/73 (47%), Gaps = 2/73 (2%)
Frame = +3
Query: 224 DLSVEGDSVTSVGWSE--RGNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNA 281
D + D VT V + + + +V ++ +++WD + GH A++ AL +
Sbjct: 405 DANAHTDWVTCVRFHQDTKNPIVVSASNDKTIKVWDNHTMTLKNTFVGHKAQITALDMST 584
Query: 282 EQLSSGSRDRMIL 294
L SGS+D + +
Sbjct: 585 NYLVSGSKDGIAM 623
>03387
Length = 1891
Score = 50.1 bits (118), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 55/256 (21%), Positives = 105/256 (41%), Gaps = 21/256 (8%)
Frame = +1
Query: 238 SERGNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNAEQLSSGSRDRMILQRD 297
SE+G G+ G ++I K++ EG R + N +++ + +L D
Sbjct: 130 SEKGEFGGFGSVSGKIEI-----EIKINH-EGEVNRARYMPQNPCIIATKTPSSDVLVFD 291
Query: 298 IRTPPLQS--------ERRLQGHRQEVCGLKWSTD-HQLLASGGNDNKLLVWNHSS---- 344
P + E RL+GH++E GL W+ + + L S +D+ + +W+ +S
Sbjct: 292 YTKHPSKPDPSGECIPELRLKGHQKEGYGLSWNPNLNGHLLSASDDHTICLWDINSTQRE 471
Query: 345 ---LSPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNT---LTGQPLQCIDT 398
+ +T H + V+ +AW L G D+ + W+T T +P +D
Sbjct: 472 SRVVDAHTIFTGHTSVVEDVAWHLLHESLF--GSVADDQKLMIWDTRSNTTSKPSHVVDA 645
Query: 399 GSQVCNLAWSKHANELVSTHGYSQNQILVWKYPSLT-QVAKLTGHSYRVLYLAMSPDGEA 457
+ N +E + G + + +W +L ++ H + + SP E
Sbjct: 646 HTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNET 825
Query: 458 IVTGAG-DETLRFWNV 472
I+ +G D L W++
Sbjct: 826 ILASSGTDRRLHVWDL 873
Score = 49.3 bits (116), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 38/154 (24%), Positives = 72/154 (46%), Gaps = 21/154 (13%)
Frame = +1
Query: 253 VQIWDA---AAGKKLSMLEGHTARVGALAWNAEQ---LSSGSRDRMILQRDIRTPPLQSE 306
+ IWD K +++ HTA V L++N L++GS D+ + D+R L+
Sbjct: 586 LMIWDTRSNTTSKPSHVVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKL- 762
Query: 307 RRLQGHRQEVCGLKWSTDHQ-LLASGGNDNKLLVWNHSSLSPVQQ--------------Y 351
+ H+ E+ ++WS ++ +LAS G D +L VW+ S + Q +
Sbjct: 763 HSFESHKDEIFQVQWSPHNETILASSGTDRRLHVWDLSKIGEEQLPEDAEDGPPELLFIH 942
Query: 352 TEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFW 385
H A + +W+P++ ++ S + D ++ W
Sbjct: 943 GGHTAKISDFSWNPNEPWIVCS--VSEDNIMQVW 1038
>19949
Length = 903
Score = 49.7 bits (117), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 36/107 (33%), Positives = 55/107 (51%)
Frame = +2
Query: 285 SSGSRDRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSS 344
+SGS D + DIR +GH VC L++S D + +AS D + +W+ ++
Sbjct: 41 ASGSMDCNVKLWDIRRKGCI--YTYKGHTGCVCCLRFSPDGRWIASASEDGLVKLWDLTA 214
Query: 345 LSPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQ 391
+ H AV I + PH+ LLAS G+ADR ++FW+ T Q
Sbjct: 215 GKLLTDLKLHRDAVNTIEFHPHEF-LLAS--GSADRTVKFWDLETFQ 346
Score = 49.7 bits (117), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 46/198 (23%), Positives = 85/198 (42%), Gaps = 6/198 (3%)
Frame = +2
Query: 232 VTSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNAEQ--LSSGSR 289
V S+ + G A G+ V++WD + +GHT V L ++ + ++S S
Sbjct: 2 VKSLDFHPYGAYTASGSMDCNVKLWDIRRKGCIYTYKGHTGCVCCLRFSPDGRWIASASE 181
Query: 290 DRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQ 349
D ++ D+ L ++ +L HR V +++ LLASG D + W+ + +
Sbjct: 182 DGLVKLWDLTAGKLLTDLKL--HRDAVNTIEFHPHEFLLASGSADRTVKFWDLETFQLIS 355
Query: 350 QYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGS----QVCNL 405
++++I + P G+ G + W +PL+ DT S QVC++
Sbjct: 356 TTEPEANSIRSILFHP--DGVCLYSGSKDTLKVYHW-----EPLELYDTVSVPWGQVCDM 514
Query: 406 AWSKHANELVSTHGYSQN 423
+ S +L+ Y N
Sbjct: 515 SISN--TQLIGASFYKTN 562
>17266
Length = 480
Score = 48.9 bits (115), Expect = 5e-06, Method: Composition-based stats.
Identities = 41/163 (25%), Positives = 67/163 (41%), Gaps = 7/163 (4%)
Frame = -1
Query: 312 HRQEVCG----LKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKAIAWSPHQ 367
H Q G L + D + SG D +W+ Q ++ H + + AI + P+
Sbjct: 474 HSQATLGT**VLSLAPDMRTFVSGACDASAKLWDVRDGMCKQTFSGHESDINAITYFPNG 295
Query: 368 HGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVC---NLAWSKHANELVSTHGYSQNQ 424
H A G+ D R ++ Q + + +C ++A+SK L+ GY
Sbjct: 294 H---AFATGSDDATCRLFDIRADQEIGMYSHDNIICGITSVAFSKSGRLLLG--GYDDFN 130
Query: 425 ILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETL 467
+W + L GH RV L ++ DG A+ TG+ D L
Sbjct: 129 CNIWDVLKQERTGVLAGHDNRVSCLGVTEDGSAVATGSWDSFL 1
Score = 32.0 bits (71), Expect = 0.53, Method: Composition-based stats.
Identities = 19/64 (29%), Positives = 31/64 (48%), Gaps = 2/64 (3%)
Frame = -1
Query: 232 VTSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALA--WNAEQLSSGSR 289
+TSV +S+ G L+ G IWD ++ +L GH RV L + +++GS
Sbjct: 192 ITSVAFSKSGRLLLGGYDDFNCNIWDVLKQERTGVLAGHDNRVSCLGVTEDGSAVATGSW 13
Query: 290 DRMI 293
D +
Sbjct: 12 DSFL 1
>16105
Length = 960
Score = 48.1 bits (113), Expect = 9e-06, Method: Compositional matrix adjust.
Identities = 33/117 (28%), Positives = 53/117 (45%), Gaps = 8/117 (6%)
Frame = -2
Query: 309 LQGHRQEVCGLKWST-DHQLLASGGNDNKLLVWN--HSSL-----SPVQQYTEHLAAVKA 360
+ GH+ V ++W + ++AS +D + VW S L PV H
Sbjct: 587 VAGHKGAVLDIQWCPHNDNVIASASDDCTVKVWQIPDSGLVTNLTDPVVDLVGHQKRCCL 408
Query: 361 IAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNLAWSKHANELVST 417
I W P +L S G AD I FWN TG+P+ +D + ++++ + + LV T
Sbjct: 407 IVWHPSAQNVLVSAG--ADNKILFWNVGTGEPMLEVDVPDMIYCMSFNFNGSRLVCT 243
>01598
Length = 1545
Score = 45.1 bits (105), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 43/185 (23%), Positives = 72/185 (38%), Gaps = 26/185 (14%)
Frame = +1
Query: 227 VEGDSVTSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWN------ 280
V+G T + WS N AVGT +G V + K ++ + + + W+
Sbjct: 967 VKGLKATELSWSPDQNAAAVGTDEGSVYVVTIQDLKIVAAIRTQQKLINCVRWHPRLTDQ 1146
Query: 281 -------AEQLSSGSRDRMILQRDIRTP------------PLQSERRLQGHRQEVCGLKW 321
L++ D++I D+ + L S R L GH Q V + W
Sbjct: 1147 SPAGSPCCHWLAAAGNDQVIHVVDLASVFAEREGDKETSLILTSLRELSGHSQRVTDMSW 1326
Query: 322 STDHQL-LASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTADR 380
S H L S G D + VW+ + + Q+ H+ + +S L+ +GG +D
Sbjct: 1327 SPHHDARLVSVGYDAEAFVWDVQKGTALAQFKGHMGRLLTCQFSGLDPDLVMTGG--SDA 1500
Query: 381 CIRFW 385
+ W
Sbjct: 1501 SVHVW 1515
>12574
Length = 521
Score = 45.1 bits (105), Expect = 7e-05, Method: Compositional matrix adjust.
Identities = 31/110 (28%), Positives = 55/110 (50%), Gaps = 2/110 (1%)
Frame = +3
Query: 267 LEGHTARVGALAW--NAEQLSSGSRDRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTD 324
L GHT + A+ + N + L+S S D++I + + E+ + GH+ + + WS+D
Sbjct: 174 LAGHTKALSAVKFSPNGDWLASSSADKLI--KIWGAYDGKFEKTIAGHKLGLSDVAWSSD 347
Query: 325 HQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKAIAWSPHQHGLLASG 374
+LL S +D L +W S+ ++ H V ++P Q L+ SG
Sbjct: 348 SKLLCSASDDKTLKIWEFSTGKCMKTLKGHSNYVFCCNFNP-QSNLIVSG 494
Score = 38.1 bits (87), Expect = 0.009, Method: Compositional matrix adjust.
Identities = 31/112 (27%), Positives = 56/112 (50%), Gaps = 3/112 (2%)
Frame = +3
Query: 354 HLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQV--CNLAWSKHA 411
H A+ A+ +SP+ L +S +AD+ I+ W G+ + I G ++ ++AWS +
Sbjct: 183 HTKALSAVKFSPNGDWLASS---SADKLIKIWGAYDGKFEKTI-AGHKLGLSDVAWSSDS 350
Query: 412 NELVSTHGYSQNQIL-VWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGA 462
L S S ++ L +W++ + + L GHS V +P IV+G+
Sbjct: 351 KLLCSA---SDDKTLKIWEFSTGKCMKTLKGHSNYVFCCNFNPQSNLIVSGS 497
Score = 36.6 bits (83), Expect = 0.021, Method: Compositional matrix adjust.
Identities = 25/103 (24%), Positives = 50/103 (48%), Gaps = 2/103 (1%)
Frame = +3
Query: 231 SVTSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNAEQ--LSSGS 288
++++V +S G+ +A + ++IW A GK + GH + +AW+++ L S S
Sbjct: 192 ALSAVKFSPNGDWLASSSADKLIKIWGAYDGKFEKTIAGHKLGLSDVAWSSDSKLLCSAS 371
Query: 289 RDRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQLLASG 331
D+ + + T + + L+GH V ++ L+ SG
Sbjct: 372 DDKTLKIWEFSTG--KCMKTLKGHSNYVFCCNFNPQSNLIVSG 494
Score = 28.5 bits (62), Expect = 5.7, Method: Compositional matrix adjust.
Identities = 10/43 (23%), Positives = 23/43 (53%)
Frame = +3
Query: 431 PSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVF 473
P+ T L GH+ + + SP+G+ + + + D+ ++ W +
Sbjct: 150 PTYTLKFTLAGHTKALSAVKFSPNGDWLASSSADKLIKIWGAY 278
>16389
Length = 558
Score = 45.1 bits (105), Expect = 8e-05, Method: Compositional matrix adjust.
Identities = 24/30 (80%), Positives = 25/30 (83%)
Frame = -3
Query: 467 LRFWNVFSKTRSTKVKWESVSVLNLFTRIR 496
LRFWNVF +TRSTK ES SVLNLFTRIR
Sbjct: 544 LRFWNVFRQTRSTK---ESKSVLNLFTRIR 464
>02960
Length = 1577
Score = 44.7 bits (104), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 66/274 (24%), Positives = 113/274 (41%), Gaps = 40/274 (14%)
Frame = +2
Query: 247 GTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNAEQLSS-------GSRDR--MILQRD 297
G++ V++W + G+ + + GHT+ V +AW SS GS D+ ++ Q
Sbjct: 533 GSYDNTVRLW-STKGEAIMTIPGHTSPVKCVAWIKHDESSGVSTFVTGSHDQTALVWQWQ 709
Query: 298 IRTPPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHS-------------- 343
T + +GH V + S D Q + +G D L +W+
Sbjct: 710 RETNEVDCRLSCRGHAASVDCVAVSPDSQQMCTGSWDKMLKLWSTDCNVDGDQSEDTERP 889
Query: 344 ------------SLSPVQQYTEHLAAVKAIAW-SPHQHGLLASGGGTADRCIRFWNTLTG 390
+ PV + H AV A+ W PH+ ++ S + D +R W+ T
Sbjct: 890 SKKKKSAKSTTQTRVPVLTLSGHAEAVSAVRWLDPHR--VVTS---SWDHSLRLWDLHTA 1054
Query: 391 QPLQCIDTGSQVCNLAWSKHANELVSTHGYSQNQI-LVWKYPSLTQVAK--LTGHSYRVL 447
Q I V ++A+S ++ L++ G + + LV S + K T H+ V
Sbjct: 1055QQTSLIQGSKAVLDVAYSPLSHMLIT--GSADRHVRLVDPRCSEGETVKCAFTSHTGWVT 1228
Query: 448 YLAMSPDGEAI-VTGAGDETLRFWNVFSKTRSTK 480
+ SP E + ++G+ D L+ W+ TRS K
Sbjct: 1229GVDWSPTREHLFLSGSYDNVLKLWD----TRSPK 1318
Score = 38.9 bits (89), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 40/141 (28%), Positives = 68/141 (48%), Gaps = 7/141 (4%)
Frame = +2
Query: 211 LWSACTSQVTRLCDLSVEGD-SVTSVGWSERGNLVAVGTHKGFVQIWD--AAAGKKL-SM 266
LW T+Q T L ++G +V V +S +++ G+ V++ D + G+ +
Sbjct: 1034 LWDLHTAQQTSL----IQGSKAVLDVAYSPLSHMLITGSADRHVRLVDPRCSEGETVKCA 1201
Query: 267 LEGHTARVGALAWNAEQ---LSSGSRDRMILQRDIRTPPLQSERRLQGHRQEVCGLKWST 323
HT V + W+ + SGS D ++ D R+P + + H + + WS
Sbjct: 1202 FTSHTGWVTGVDWSPTREHLFLSGSYDNVLKLWDTRSPK-ATLYDMNWHEDRILAVDWSI 1378
Query: 324 DHQLLASGGNDNKLLVWNHSS 344
+LL SGG DNKL V+++SS
Sbjct: 1379 P-ELLLSGGVDNKLHVFSYSS 1438
>01805
Length = 2124
Score = 43.5 bits (101), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 52/244 (21%), Positives = 101/244 (41%), Gaps = 12/244 (4%)
Frame = -1
Query: 241 GNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNAEQLSSGSRDRMILQRDIRT 300
GN VA+G+ + ++IWD L ++E VG L+ GS+ + ++
Sbjct: 726 GNFVAIGSMEPVIEIWD------LDIMES----VGP------TLTLGSKPKKTKKK---- 607
Query: 301 PPLQSERRLQGHRQEVCGLKWSTD-HQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVK 359
++ + + GH Q V L W+ + +LAS D + +W+ S +T+H V+
Sbjct: 606 --MKQKESVTGHTQAVLDLSWNRNARHVLASASADTTVALWDLSEGKMAMNFTQHSREVQ 433
Query: 360 AIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNLAWS----------K 409
W P + L +G F NT+ + + C ++ C+ +W+
Sbjct: 432 CCNWHPQEEQTLLTGS--------FDNTV--KVVDC--RSAETCHKSWTVEGEVEKAVWN 289
Query: 410 HANELVSTHGYSQNQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAI-VTGAGDETLR 468
H N L + + + V + HS V + +S + +T + D+T++
Sbjct: 288 HHNPLQLLACTDKGMVYCFDIRHEKPVFSVGAHSSCVTGVCLSSQIPGLMITTSEDKTMK 109
Query: 469 FWNV 472
W++
Sbjct: 108 VWDI 97
>01249
Length = 1743
Score = 43.1 bits (100), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 38/124 (30%), Positives = 55/124 (44%), Gaps = 14/124 (11%)
Frame = -1
Query: 235 VGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNAEQ--LSSGSRDRM 292
VG VA + G ++WD +G L + T VG L + ++ L +G +
Sbjct: 1188 VGCGGPAARVASSSSDGTCKLWDMLSGALLRTMVYETG-VGCLIMDKQEHFLLAGLDNGD 1012
Query: 293 ILQRDIRTPPLQSE------------RRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVW 340
IL + QSE R LQGH V L +S+D Q LASG + K+++W
Sbjct: 1011 ILCSPLFGQISQSEVFVSKHTTKAGERVLQGHSDAVTCLAFSSDGQRLASGSQNGKVIIW 832
Query: 341 NHSS 344
N S
Sbjct: 831 NMES 820
Score = 36.6 bits (83), Expect = 0.025, Method: Compositional matrix adjust.
Identities = 53/269 (19%), Positives = 95/269 (35%), Gaps = 3/269 (1%)
Frame = -1
Query: 209 VYLWSACT-SQVTRLCDLSVEGDSVTSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSML 267
+Y+W S V L D + T + +++ G+ V T G + IWD A
Sbjct: 1422 IYIWEMTGGSLVGLLSDF----NEATKIQFTDDGSQFVVATSSGHLNIWDFA-------- 1279
Query: 268 EGHTARVGALAWNAEQLSSGSRDRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQL 327
R++ R L+ R + H + + GL
Sbjct: 1278 -----------------------RVVTTTSQRARGLKPGRTINAHSEPITGLHVGCGGPA 1168
Query: 328 --LASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFW 385
+AS +D +W+ S + ++ + V + +H LLA
Sbjct: 1167 ARVASSSSDGTCKLWDMLSGALLRTMV-YETGVGCLIMDKQEHFLLAG------------ 1027
Query: 386 NTLTGQPLQCIDTGSQVCNLAWSKHANELVSTHGYSQNQILVWKYPSLTQVAKLTGHSYR 445
+D G +C+ + + SQ+++ V K+ + L GHS
Sbjct: 1026 ----------LDNGDILCSPLFGQ----------ISQSEVFVSKHTTKAGERVLQGHSDA 907
Query: 446 VLYLAMSPDGEAIVTGAGDETLRFWNVFS 474
V LA S DG+ + +G+ + + WN+ S
Sbjct: 906 VTCLAFSSDGQRLASGSQNGKVIIWNMES 820
>15780
Length = 735
Score = 41.6 bits (96), Expect = 7e-04, Method: Compositional matrix adjust.
Identities = 21/60 (35%), Positives = 34/60 (56%)
Frame = -1
Query: 413 ELVSTHGYSQNQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNV 472
+ +ST G + + ++VW S T VA LT H+ V L S DG + +G D ++R W++
Sbjct: 735 KYLSTAG-ADHTVIVWDIASGTAVAHLTAHTDTVYALCFSRDGTVLASGGMDNSIRLWDL 559
Score = 34.3 bits (77), Expect = 0.12, Method: Compositional matrix adjust.
Identities = 19/60 (31%), Positives = 30/60 (50%)
Frame = -1
Query: 282 EQLSSGSRDRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWN 341
+ LS+ D ++ DI + + L H V L +S D +LASGG DN + +W+
Sbjct: 735 KYLSTAGADHTVIVWDIASG--TAVAHLTAHTDTVYALCFSRDGTVLASGGMDNSIRLWD 562
Score = 29.6 bits (65), Expect = 3.2, Method: Compositional matrix adjust.
Identities = 16/43 (37%), Positives = 23/43 (53%), Gaps = 2/43 (4%)
Frame = -1
Query: 253 VQIWDAAAGKKLSMLEGHTARVGALAW--NAEQLSSGSRDRMI 293
V +WD A+G ++ L HT V AL + + L+SG D I
Sbjct: 702 VIVWDIASGTAVAHLTAHTDTVYALCFSRDGTVLASGGMDNSI 574
>30295
Length = 593
Score = 40.0 bits (92), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 21/73 (28%), Positives = 38/73 (52%)
Frame = +2
Query: 303 LQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKAIA 362
+++ R L+ H ++ + W+TD + L S D KL+VW+ + + V + V A
Sbjct: 215 MRTRRTLRXHLAKIYAMHWATDSRNLVSASQDGKLIVWDGYTTNKVHAIPLRSSWVMTCA 394
Query: 363 WSPHQHGLLASGG 375
++P G +A GG
Sbjct: 395 YAP-SGGYVACGG 430
>14555
Length = 627
Score = 39.7 bits (91), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 29/86 (33%), Positives = 40/86 (46%), Gaps = 7/86 (8%)
Frame = -3
Query: 417 THGYSQNQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFW------ 470
T+ Y+ N VW + L GH RV L +SPDG ++ TG+ D TLR W
Sbjct: 409 TNDYTVN---VWDALKGMRSTILYGHDNRVSCLRISPDGTSLCTGSWDYTLRIWA*ERER 239
Query: 471 -NVFSKTRSTKVKWESVSVLNLFTRI 495
+ + R T WE L +FT +
Sbjct: 238 GHSSNIIRITL*TWEQCQ*LCVFTWV 161
Score = 28.5 bits (62), Expect = 6.1, Method: Compositional matrix adjust.
Identities = 16/45 (35%), Positives = 24/45 (53%), Gaps = 2/45 (4%)
Frame = -3
Query: 248 THKGFVQIWDAAAGKKLSMLEGHTARVGAL--AWNAEQLSSGSRD 290
T+ V +WDA G + ++L GH RV L + + L +GS D
Sbjct: 409 TNDYTVNVWDALKGMRSTILYGHDNRVSCLRISPDGTSLCTGSWD 275
>18981
Length = 407
Score = 38.1 bits (87), Expect = 0.007, Method: Composition-based stats.
Identities = 28/95 (29%), Positives = 44/95 (46%), Gaps = 1/95 (1%)
Frame = -2
Query: 309 LQGHRQEV-CGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKAIAWSPHQ 367
L+GH +V C + + + SG D L+VW + PV Q H A+ A+ + +
Sbjct: 310 LRGHNDDVECVCIYG---RRVVSGSWDKTLIVWEVDTGRPVHQLHGHTEAITAVQFDEGK 140
Query: 368 HGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQV 402
+ G+AD +R W TGQ L + TG +
Sbjct: 139 -----AVSGSADGDVRTWALDTGQCLLTMTTGQDI 50
Score = 30.4 bits (67), Expect = 1.7, Method: Composition-based stats.
Identities = 18/65 (27%), Positives = 31/65 (47%)
Frame = -2
Query: 241 GNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNAEQLSSGSRDRMILQRDIRT 300
G V G+ + +W+ G+ + L GHT + A+ ++ + SGS D D+RT
Sbjct: 268 GRRVVSGSWDKTLIVWEVDTGRPVHQLHGHTEAITAVQFDEGKAVSGSAD-----GDVRT 104
Query: 301 PPLQS 305
L +
Sbjct: 103 WALDT 89
>10264
Length = 416
Score = 38.1 bits (87), Expect = 0.009, Method: Compositional matrix adjust.
Identities = 25/84 (29%), Positives = 38/84 (45%), Gaps = 1/84 (1%)
Frame = -1
Query: 303 LQSERRLQGHRQEVCGLKWSTDHQL-LASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKAI 361
L S R L GH Q V + WS H L S G D + VW+ + + Q+ H+ +
Sbjct: 275 LTSLRELSGHSQRVTDMSWSPHHDARLVSVGYDAEAFVWDVQKGTALAQFKGHMGRLLTC 96
Query: 362 AWSPHQHGLLASGGGTADRCIRFW 385
+S L+ +GG +D + W
Sbjct: 95 QFSGLDPDLVMTGG--SDASVHVW 30
Score = 28.9 bits (63), Expect = 4.5, Method: Compositional matrix adjust.
Identities = 19/58 (32%), Positives = 29/58 (50%), Gaps = 2/58 (3%)
Frame = -1
Query: 219 VTRLCDLSVEGDSVTSVGWSERGN--LVAVGTHKGFVQIWDAAAGKKLSMLEGHTARV 274
+T L +LS VT + WS + LV+VG + +WD G L+ +GH R+
Sbjct: 275 LTSLRELSGHSQRVTDMSWSPHHDARLVSVG-YDAEAFVWDVQKGTALAQFKGHMGRL 105
>01768
Length = 1424
Score = 37.0 bits (84), Expect = 0.018, Method: Compositional matrix adjust.
Identities = 54/233 (23%), Positives = 94/233 (40%), Gaps = 23/233 (9%)
Frame = +3
Query: 221 RLCDLSVEGDSVTSVGWSERGNLVAVGTHKGFVQIWDAAAGKK--------LSMLEGHTA 272
R+ D++ D + + WS++G++ + DA A K + + HT
Sbjct: 534 RVTDIN---DKIYTGSWSDKGSVYVYDITXQTAIVDDAEAAGKYDSTQKSIVHTVTHHTT 704
Query: 273 RVGALAWNAEQ---LSSGSRDRMILQRDIRTPPLQSERR-LQGHRQEVCGLKWSTDH-QL 327
A+ W+ L +G I + +E+ H V ++WS + +
Sbjct: 705 EGFAIDWSPAAKGWLVTGDCTGAIYISQPSSSGWTTEKSSYAAHTDSVEDVQWSPNEGNV 884
Query: 328 LASGGNDNKLLVWN---HSSLSPVQQYTE-HLAAVKAIAWSPHQHGLLASGGGTADRCIR 383
AS D L +WN S + V E H + I W+P + LLASGG D I+
Sbjct: 885 FASCSVDRTLRIWNTQQKPSKANVLTVPEAHSRDINVINWNPIEKHLLASGGD--DGIIK 1058
Query: 384 FWN--TLTGQPLQC---IDTGSQ-VCNLAWSKHANELVSTHGYSQNQILVWKY 430
W+ +P+ SQ V +L W+ + +++ G +QI +W +
Sbjct: 1059IWDLRMFRNKPVSAQASFKLHSQPVTSLEWNPQDSSVLAASG-EDDQITIWDF 1214
>27475
Length = 369
Score = 37.0 bits (84), Expect = 0.019, Method: Compositional matrix adjust.
Identities = 26/78 (33%), Positives = 40/78 (51%), Gaps = 3/78 (3%)
Frame = +2
Query: 270 HTARVGALAWNAEQ---LSSGSRDRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQ 326
HT V + W+ + SGS D ++ D R+P + + H + + WS +
Sbjct: 65 HTGWVTGVDWSPTREHLFLSGSYDNVLKLWDTRSPK-ATLYDMNWHEDRILAVDWSIP-E 238
Query: 327 LLASGGNDNKLLVWNHSS 344
LL SGG DNKL V+++SS
Sbjct: 239 LLLSGGVDNKLHVFSYSS 292
>19863
Length = 502
Score = 36.6 bits (83), Expect = 0.022, Method: Compositional matrix adjust.
Identities = 26/75 (34%), Positives = 34/75 (45%)
Frame = +1
Query: 283 QLSSGSRDRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNH 342
QL SGS D I+ D+ + RLQGH V + +S D L S NDN + +WN
Sbjct: 13 QLVSGSSDMSIVVWDVENGV--QKLRLQGHAGWVNDVHFSQDQCWLLSCSNDNTVRIWNI 186
Query: 343 SSLSPVQQYTEHLAA 357
+ EH A
Sbjct: 187 EESDQIPIVMEHKRA 231
Score = 33.5 bits (75), Expect = 0.19, Method: Compositional matrix adjust.
Identities = 20/60 (33%), Positives = 32/60 (53%)
Frame = +1
Query: 413 ELVSTHGYSQNQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNV 472
+LVS G S I+VW + Q +L GH+ V + S D +++ + D T+R WN+
Sbjct: 13 QLVS--GSSDMSIVVWDVENGVQKLRLQGHAGWVNDVHFSQDQCWLLSCSNDNTVRIWNI 186
>31474
Length = 403
Score = 36.6 bits (83), Expect = 0.023, Method: Composition-based stats.
Identities = 27/111 (24%), Positives = 45/111 (40%), Gaps = 5/111 (4%)
Frame = -3
Query: 217 SQVTRLCDLSVEGDSVTSVGWSERGNLVAVGTHKGFVQIWDAAAGK---KLSMLEGHTAR 273
+ + +C LS + V W+ G L+A ++IW K ++ + HT
Sbjct: 341 ATLEEVCCLSAHDEHAWCVAWNPTGTLLASCGSDKIIKIWGKEGDNWVCKSTLTDAHTRT 162
Query: 274 VGALAWN--AEQLSSGSRDRMILQRDIRTPPLQSERRLQGHRQEVCGLKWS 322
V +L W+ LSS S D + + L+GH EV + W+
Sbjct: 161 VRSLGWSPCGNYLSSASFDATTAVWSRKGGEFECIATLEGHENEVKAVAWA 9
Score = 32.0 bits (71), Expect = 0.65, Method: Composition-based stats.
Identities = 27/108 (25%), Positives = 50/108 (46%), Gaps = 7/108 (6%)
Frame = -3
Query: 309 LQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYT---EHLAAVKAIAWSP 365
L H + + W+ LLAS G+D + +W + V + T H V+++ WSP
Sbjct: 317 LSAHDEHAWCVAWNPTGTLLASCGSDKIIKIWGKEGDNWVCKSTLTDAHTRTVRSLGWSP 138
Query: 366 HQHGLLASGGGTADRCIRFWNTLTGQPLQCIDT----GSQVCNLAWSK 409
+ L ++ + D W+ G+ +CI T ++V +AW++
Sbjct: 137 CGNYLSSA---SFDATTAVWSRKGGE-FECIATLEGHENEVKAVAWAR 6
>02090
Length = 1841
Score = 36.2 bits (82), Expect = 0.034, Method: Compositional matrix adjust.
Identities = 18/52 (34%), Positives = 27/52 (51%)
Frame = -3
Query: 421 SQNQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNV 472
S I VW + T V + GH+ + +SPDG + TG D T+R W++
Sbjct: 1566 SDGNIAVWDLHNQTLVRQFQGHTDGASCIDISPDGTKLWTGGLDNTVRSWDL 1411
Score = 28.5 bits (62), Expect = 6.4, Method: Compositional matrix adjust.
Identities = 38/167 (22%), Positives = 67/167 (40%)
Frame = -3
Query: 307 RRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKAIAWSPH 366
R+ QGH + S D L +GG DN + W+ +QQ+ + + + ++ + P
Sbjct: 1518 RQFQGHTDGASCIDISPDGTKLWTGGLDNTVRSWDLREGRQLQQH-DFSSQIFSLGYCPT 1342
Query: 367 QHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNLAWSKHANELVSTHGYSQNQIL 426
L G + + Q S V +L ++ VST N +
Sbjct: 1341 GEWLAV---GMESSNVEVLHHSKPDKYQLHLHESCVLSLKFAYCGKWFVSTG--KDNLLN 1177
Query: 427 VWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVF 473
W+ P + + + S VL ++ D + IVTG+GD+ + V
Sbjct: 1176 AWRTPYGASIFQ-SKESSSVLSCDIAADDKYIVTGSGDKKATLYEVI 1039
>13278
Length = 870
Score = 35.8 bits (81), Expect = 0.038, Method: Compositional matrix adjust.
Identities = 26/115 (22%), Positives = 49/115 (42%), Gaps = 9/115 (7%)
Frame = +1
Query: 309 LQGHRQEVCGLKWS---------TDHQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVK 359
LQ +E+ +KWS +LAS D+ + +W + T+H V
Sbjct: 37 LQLTTKEIYTIKWSPTGPGTSNPNTSLILASASFDSTVRLWEVERGLCLHTLTKHQEPVY 216
Query: 360 AIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNLAWSKHANEL 414
++A+SP L + G+ D+C+ WN TG + + + W+ +++
Sbjct: 217 SVAFSPDGKYLAS---GSFDKCVHIWNVQTGSLVHSYKGTGGIFEVCWNHRGDKV 372
Score = 33.5 bits (75), Expect = 0.23, Method: Compositional matrix adjust.
Identities = 14/34 (41%), Positives = 21/34 (61%)
Frame = +1
Query: 439 LTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNV 472
LT H V +A SPDG+ + +G+ D+ + WNV
Sbjct: 190 LTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNV 291
Score = 30.0 bits (66), Expect = 2.1, Method: Compositional matrix adjust.
Identities = 26/94 (27%), Positives = 41/94 (43%), Gaps = 9/94 (9%)
Frame = +1
Query: 309 LQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKAIAWSPH-- 366
L H++ V + +S D + LASG D + +WN + S V Y + + + W+
Sbjct: 190 LTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNVQTGSLVHSY-KGTGGIFEVCWNHRGD 366
Query: 367 QHGLLASGGGTA-------DRCIRFWNTLTGQPL 393
+ G AS G D+C W+ L PL
Sbjct: 367 KVGASASDGSVFVLDLRK*DKCSNSWHMLLLPPL 468
>01462
Length = 995
Score = 35.8 bits (81), Expect = 0.045, Method: Compositional matrix adjust.
Identities = 27/111 (24%), Positives = 49/111 (44%), Gaps = 12/111 (10%)
Frame = +2
Query: 253 VQIWDAAAGKKLSMLEGHTARVGALAW--NAEQLSSGSRDRMILQRDIRTPPLQSERRLQ 310
+ +WD AG+ L+ +EGH + + +A++ S S D + DIR+ ++ L+
Sbjct: 269 IHVWDIEAGQYLNAMEGHKDYIHKVVMKNDAQECVSASEDGTVRMWDIRS-STETVHCLE 445
Query: 311 GHRQEVCG----------LKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQY 351
+ E+C L + L GG KL W+ +L+P +
Sbjct: 446 PSKNELCSRPLLGKWLRCLALDPEEGWLVCGGGP-KLSAWHLRTLAPTTIF 595
Score = 32.3 bits (72), Expect = 0.50, Method: Compositional matrix adjust.
Identities = 15/61 (24%), Positives = 28/61 (45%)
Frame = +2
Query: 419 GYSQNQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKTRS 478
G +I VW + + + GH + + M D + V+ + D T+R W++ S T +
Sbjct: 251 GAGDRKIHVWDIEAGQYLNAMEGHKDYIHKVVMKNDAQECVSASEDGTVRMWDIRSSTET 430
Query: 479 T 479
Sbjct: 431 V 433
>26107
Length = 1338
Score = 35.8 bits (81), Expect = 0.045, Method: Compositional matrix adjust.
Identities = 59/256 (23%), Positives = 96/256 (37%), Gaps = 36/256 (14%)
Frame = -3
Query: 253 VQIWDAAAGKKLSMLEGHTARVGALAW---NAEQLSSGSRDRMILQRDIRTPPLQSERRL 309
V +WD K++ GH V ++A + Q +SG+RD I+ D R + +R
Sbjct: 1015 VALWDVETTTKVTTFIGHKCSVRSVASCPSSPAQCASGARDGHIMLWDSR---VNKKREH 845
Query: 310 QGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAA--------VKAI 361
Q Q HQ+ G+ +K P + H AA +++
Sbjct: 844 QPCSQV---------HQVCPQSGHQSK----------PAKHRRIHRAAGPKGVMDTQQSV 722
Query: 362 AWSPHQHGLLASGGGTADRCIRFW-------NTLTG--QPLQCIDTGSQV---------C 403
+Q L G D C++ W NT T P+ D + C
Sbjct: 721 TCVLYQTDNLIISSGANDGCVKMWDTRKWYTNTTTSLPVPVHTFDYPGHMRRLKGIVTMC 542
Query: 404 NLAWSKHANELVSTHGYSQNQILVWKYPSLTQVAK-----LTGHSYRVLYL--AMSPDGE 456
W + VS Y+ N+ V++Y Q + GH ++ A+SPDG+
Sbjct: 541 MDPWK--SQLFVS---YTDNK--VYRYQLAGQYREPQEYVYAGHRNDTFFVRCAISPDGK 383
Query: 457 AIVTGAGDETLRFWNV 472
+++G+G T W V
Sbjct: 382 YLLSGSGRNTGVIWEV 335
Score = 30.8 bits (68), Expect = 1.4, Method: Compositional matrix adjust.
Identities = 22/81 (27%), Positives = 35/81 (43%), Gaps = 1/81 (1%)
Frame = -3
Query: 308 RLQGHRQEVCGLKW-STDHQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKAIAWSPH 366
R H V W S D Q L + G D + +W+ + + V + H +V+++A P
Sbjct: 1102 RWXAHNNAVFDYSWISNDSQCLTASG-DQTVALWDVETTTKVTTFIGHKCSVRSVASCPS 926
Query: 367 QHGLLASGGGTADRCIRFWNT 387
ASG D I W++
Sbjct: 925 SPAQCASGA--RDGHIMLWDS 869
>37142
Length = 327
Score = 35.0 bits (79), Expect = 0.071, Method: Compositional matrix adjust.
Identities = 27/104 (25%), Positives = 51/104 (49%), Gaps = 12/104 (11%)
Frame = +2
Query: 327 LLASGGNDNKLLVWNHSSL------SPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTADR 380
++ G ++ +LV++ + V Q T+H AVKA+ ++P Q LLASG ++
Sbjct: 2 VIVGGADNGSVLVYSAQKMIDGDADCSVLQLTKHTGAVKALDFNPFQTNLLASGASESE- 178
Query: 381 CIRFW------NTLTGQPLQCIDTGSQVCNLAWSKHANELVSTH 418
I W N +T P Q +V +AW++ +++++
Sbjct: 179 -IYIWDLNKPDNPMT--PGQKSQPPEEVSCVAWNRQVQHILASN 301
>31054
Length = 392
Score = 34.7 bits (78), Expect = 0.084, Method: Compositional matrix adjust.
Identities = 16/51 (31%), Positives = 30/51 (58%)
Frame = -2
Query: 421 SQNQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWN 471
S + + WK+P + L+GH+ + LA++ DG +V+GA + T+ W+
Sbjct: 355 SPDXVKQWKFPDGNFIQNLSGHNAIINTLAVNSDG-VLVSGADNGTMHLWD 206
>21921
Length = 1341
Score = 34.3 bits (77), Expect = 0.12, Method: Compositional matrix adjust.
Identities = 19/77 (24%), Positives = 37/77 (48%)
Frame = -1
Query: 351 YTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNLAWSKH 410
Y H V++I P L++ G+ D IRFW +G+ ++ + G V ++AW+ +
Sbjct: 495 YKGHTGIVRSICPDPTGQWLVS---GSDDGTIRFWEVSSGRCMKTLQVGGCVTSVAWNPN 325
Query: 411 ANELVSTHGYSQNQILV 427
+ V + +L+
Sbjct: 324 PSLCVVAATLNTTVLLI 274
Score = 33.5 bits (75), Expect = 0.19, Method: Compositional matrix adjust.
Identities = 16/41 (39%), Positives = 23/41 (56%)
Frame = -1
Query: 434 TQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFS 474
TQ GH+ V + P G+ +V+G+ D T+RFW V S
Sbjct: 510 TQALVYKGHTGIVRSICPDPTGQWLVSGSDDGTIRFWEVSS 388
>12140
Length = 727
Score = 34.3 bits (77), Expect = 0.13, Method: Compositional matrix adjust.
Identities = 30/106 (28%), Positives = 46/106 (43%), Gaps = 9/106 (8%)
Frame = +2
Query: 247 GTHKGFVQIW--DAAAGKKLSMLEGHTARVGALAWNA------EQLSSGSRD-RMILQRD 297
G V+IW D + LEGH+ V +AW ++S S+D R+I+ +
Sbjct: 278 GGCDNLVKIWREDETGWVEDQKLEGHSDWVRDVAWAPSIGLPRNVIASCSQDCRVIIWTN 457
Query: 298 IRTPPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHS 343
+ + R L V + WS +LA G DNK+ +W S
Sbjct: 458 DGSSNQWTSRILNKFSDVVWHVSWSVTGNILAVSGGDNKVTLWKES 595
>34511
Length = 1037
Score = 33.5 bits (75), Expect = 0.23, Method: Compositional matrix adjust.
Identities = 16/38 (42%), Positives = 22/38 (57%)
Frame = +3
Query: 439 LTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKT 476
L GH RV L ++ +G ++ TG+ D LR WN S T
Sbjct: 60 LAGHDNRVSCLGVTENGMSVATGSWDSFLRVWN*VSCT 173
>19140
Length = 573
Score = 33.1 bits (74), Expect = 0.29, Method: Compositional matrix adjust.
Identities = 13/38 (34%), Positives = 24/38 (63%)
Frame = -3
Query: 435 QVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNV 472
++ KL GH+ V L ++ DG ++G+ D T+R W++
Sbjct: 511 KLMKLKGHTDNVKALVLNRDGTQCLSGSSDGTIRLWSL 398
>15337
Length = 860
Score = 32.7 bits (73), Expect = 0.34, Method: Compositional matrix adjust.
Identities = 15/49 (30%), Positives = 26/49 (53%)
Frame = -1
Query: 427 VWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSK 475
V+ Y S+ + + + +L + SPDG+ IVTG D+ + W+ K
Sbjct: 251 VFNYNSMELIGTMKSYFGGLLCVCWSPDGKYIVTGGEDDLVTVWSFHEK 105
Score = 28.1 bits (61), Expect = 7.5, Method: Compositional matrix adjust.
Identities = 13/46 (28%), Positives = 23/46 (50%)
Frame = -1
Query: 321 WSTDHQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKAIAWSPH 366
WS D + + +GG D+ + VW+ V + H + V +A+ H
Sbjct: 179 WSPDGKYIVTGGEDDLVTVWSFHEKRVVCRGHGHKSWVNVVAFDIH 42
>21105
Length = 650
Score = 32.7 bits (73), Expect = 0.36, Method: Compositional matrix adjust.
Identities = 14/41 (34%), Positives = 25/41 (60%)
Frame = +1
Query: 436 VAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKT 476
+ + H V LA+ P+G +++G+ D ++R WN+ SKT
Sbjct: 169 IHAMVAHLDSVTSLAVDPNGLYLLSGSHDCSIRLWNLDSKT 291
Score = 28.5 bits (62), Expect = 7.0, Method: Compositional matrix adjust.
Identities = 27/97 (27%), Positives = 40/97 (41%), Gaps = 4/97 (4%)
Frame = +1
Query: 286 SGSRDRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSL 345
+ DR I D T L + H V L + L SG +D + +WN S
Sbjct: 115 TAHEDRHIRFFDNNTGKLI--HAMVAHLDSVTSLAVDPNGLYLLSGSHDCSIRLWNLDSK 288
Query: 346 SPVQQYTEHL----AAVKAIAWSPHQHGLLASGGGTA 378
+ VQ+ T H ++ +A+ P Q +AS G A
Sbjct: 289 TCVQEITSHRKKFDESIHDVAFHP-QKPYIASAGADA 396
>15972
Length = 1069
Score = 32.7 bits (73), Expect = 0.37, Method: Compositional matrix adjust.
Identities = 14/33 (42%), Positives = 20/33 (60%)
Frame = +3
Query: 439 LTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWN 471
+GH V +LA+ P G+ +T + D TLR WN
Sbjct: 225 FSGHKGPVRHLAVHPSGKLTLTVSQDRTLRLWN 323
>01584
Length = 1540
Score = 32.7 bits (73), Expect = 0.38, Method: Compositional matrix adjust.
Identities = 17/51 (33%), Positives = 27/51 (52%), Gaps = 1/51 (1%)
Frame = -2
Query: 384 FWNTLTGQPLQCIDTGSQVCNLAW-SKHANELVSTHGYSQNQILVWKYPSL 433
FW +TG+ L C VC W +HA ++S H S+ ++ ++PSL
Sbjct: 678 FWLIITGKHLACTRGNHGVCLAPW*REHAVAVLSHHARSKVRVTSCQHPSL 526
>21025
Length = 444
Score = 32.3 bits (72), Expect = 0.48, Method: Compositional matrix adjust.
Identities = 13/41 (31%), Positives = 24/41 (58%)
Frame = +1
Query: 14 VIQNENTMPRVTEMRRTLTPASSPVSSPSKHGDRFIPSRAG 54
V++ ++T+ ++ + L P+ SPV +KHG +I S A
Sbjct: 127 VLRQQHTVDTISRLMLVL*PSYSPVCQHAKHGKLYIISMAA 249
>15118
Length = 1074
Score = 32.3 bits (72), Expect = 0.50, Method: Compositional matrix adjust.
Identities = 29/123 (23%), Positives = 54/123 (43%), Gaps = 4/123 (3%)
Frame = +3
Query: 354 HLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQP----LQCIDTGSQVCNLAWSK 409
H++ V+ +A+ LL + GG D I+FW + L+ + + + +
Sbjct: 189 HVSGVRGVAFDAFN-CLLITAGGDCD--IKFWRFGSRDRARVLLKELKMSEGISRILLHR 359
Query: 410 HANELVSTHGYSQNQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRF 469
+N L + V +L V +GHS + L+ S DG ++T + D T+R
Sbjct: 360 DSNMLAVV--LEDFTVSVIDVDTLRVVRVFSGHSNSITDLSFSGDGRWLITASMDCTVRT 533
Query: 470 WNV 472
W++
Sbjct: 534 WSL 542
>36111
Length = 687
Score = 31.6 bits (70), Expect = 0.77, Method: Compositional matrix adjust.
Identities = 14/48 (29%), Positives = 22/48 (45%)
Frame = +2
Query: 232 VTSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAW 279
V +V + N A G G+V IWD K+L + + +LA+
Sbjct: 239 VNAVAFHNVYNTFATGGSDGYVNIWDGFHKKRLCXFHRYPTSIASLAF 382
>27270
Length = 1078
Score = 31.2 bits (69), Expect = 0.94, Method: Compositional matrix adjust.
Identities = 25/91 (27%), Positives = 40/91 (43%), Gaps = 6/91 (6%)
Frame = +2
Query: 310 QGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKAIAWSPHQHG 369
+GH + V + W D + L S D ++ WN ++L ++++ A S HG
Sbjct: 263 KGHSKAVTDMCWRADGRTLYSSSLDGHVIGWNVNTLHMIEKWK---------ATSGRHHG 415
Query: 370 L----LASGGG--TADRCIRFWNTLTGQPLQ 394
+ L S TAD I+ W+ T LQ
Sbjct: 416 VHCVCLCSSSRLLTADHTIKMWDLTTKNVLQ 508
>10162
Length = 1629
Score = 31.2 bits (69), Expect = 1.0, Method: Compositional matrix adjust.
Identities = 20/88 (22%), Positives = 42/88 (47%), Gaps = 2/88 (2%)
Frame = +3
Query: 391 QPLQCIDTGSQVCNLAWSKHANELVSTHGYSQNQILVWKYPS--LTQVAKLTGHSYRVLY 448
Q + + GS + L W A+ L++ G ++ +W+ PS +++ L H L
Sbjct: 3 QQIWSYECGSDITWLQWHGGAHVLLA--GTQGGEVWLWQVPSQDYSKMKMLQSHGQPSLC 176
Query: 449 LAMSPDGEAIVTGAGDETLRFWNVFSKT 476
+ P+G+ + G D ++ W++ + T
Sbjct: 177 GKILPNGKYVCVGYSDGVVKLWDLKTGT 260
Score = 28.9 bits (63), Expect = 4.6, Method: Compositional matrix adjust.
Identities = 18/65 (27%), Positives = 30/65 (46%), Gaps = 4/65 (6%)
Frame = +3
Query: 230 DSVTSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNAEQ----LS 285
+ V + WS L+ G +++WDA +G ++L GH L ++ + L
Sbjct: 645 EGVCKLQWSSSTALLYTACLDGVMRVWDARSGASKAVLTGHARNSCILDFDVTRDGTCLV 824
Query: 286 SGSRD 290
SGS D
Sbjct: 825 SGSED 839
>11493
Length = 535
Score = 31.2 bits (69), Expect = 1.1, Method: Compositional matrix adjust.
Identities = 38/163 (23%), Positives = 68/163 (41%), Gaps = 6/163 (3%)
Frame = -2
Query: 312 HRQEVCGLKWSTDHQLLASGGNDNKLLVWNHS---SLSPVQQY--TEHLAAVKAIAWSPH 366
H + VC + S + + +GG + VW+ S + +PV Q + ++++ P
Sbjct: 480 HGEVVCAVTISNPTKYVYTGGK-GCVKVWDISQPGNKNPVSQLDCLQRDNYIRSVKLLPD 304
Query: 367 QHGLLASGGGTADRCIRFWNTLTGQP-LQCIDTGSQVCNLAWSKHANELVSTHGYSQNQI 425
L+ GG A + W+ + P ++ T + A + + V S I
Sbjct: 303 GRTLIV--GGEASN-LSIWDLASPTPRIKAELTSAAPACYALAISPDSKVCFSCCSDGNI 133
Query: 426 LVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLR 468
VW + V + GH+ + +SPDG + TG D T+R
Sbjct: 132 AVWDLHNEILVRQFQGHTDGASCIDISPDGSRLWTGGLDNTVR 4
>27681
Length = 465
Score = 30.8 bits (68), Expect = 1.4, Method: Compositional matrix adjust.
Identities = 12/31 (38%), Positives = 19/31 (61%)
Frame = +2
Query: 446 VLYLAMSPDGEAIVTGAGDETLRFWNVFSKT 476
V A +P + + +G+GD T R WN+ S+T
Sbjct: 2 VFICAWNPTNDLLASGSGDSTARIWNMTSET 94
Score = 30.4 bits (67), Expect = 1.5, Method: Compositional matrix adjust.
Identities = 10/25 (40%), Positives = 18/25 (72%)
Frame = +2
Query: 232 VTSVGWSERGNLVAVGTHKGFVQIW 256
VTS+ W+ G L+A G++ G+ ++W
Sbjct: 170 VTSLDWNSEGTLLATGSYDGYARLW 244
Score = 29.3 bits (64), Expect = 4.2, Method: Compositional matrix adjust.
Identities = 14/44 (31%), Positives = 21/44 (47%)
Frame = +3
Query: 308 RLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQY 351
R R + LKW+ + S G D ++W+ SS S QQ+
Sbjct: 270 RWVNTRAPIFALKWNKRGNYILSAGVDKTTIIWDASSGSCTQQF 401
>07665
Length = 435
Score = 30.4 bits (67), Expect = 1.6, Method: Compositional matrix adjust.
Identities = 30/102 (29%), Positives = 43/102 (42%), Gaps = 14/102 (13%)
Frame = -2
Query: 256 WDAAAGKKLSMLEGHTARVGALAWNAEQLSSGSRDRMILQR--DIRTPPLQSERRLQGHR 313
WD GK L LE H + AL + S +R + + I+ L ++ ++ R
Sbjct: 392 WDLNDGKNLYTLE-HNDIINALCF------SPNRYWLCVAYGPSIKIWDLACKKTVEELR 234
Query: 314 QEVCG------------LKWSTDHQLLASGGNDNKLLVWNHS 343
EV L WSTD Q L +G +DN + VW S
Sbjct: 233 PEVVSPTSKAEQPQCLSLAWSTDGQTLFAGYSDNTIRVWQVS 108
Score = 28.9 bits (63), Expect = 4.3, Method: Compositional matrix adjust.
Identities = 12/28 (42%), Positives = 16/28 (57%)
Frame = -2
Query: 445 RVLYLAMSPDGEAIVTGAGDETLRFWNV 472
+ L LA S DG+ + G D T+R W V
Sbjct: 194 QCLSLAWSTDGQTLFAGYSDNTIRVWQV 111
>28289
Length = 349
Score = 29.6 bits (65), Expect = 2.6, Method: Composition-based stats.
Identities = 24/86 (27%), Positives = 41/86 (47%), Gaps = 5/86 (5%)
Frame = -1
Query: 259 AAGKKLSM---LEGHTARVGALAWNA--EQLSSGSRDRMILQRDIRTPPLQSERRLQGHR 313
AA LSM LEGH+ V +AWN ++L++ + +I+ + E ++
Sbjct: 277 AAPSNLSMNQSLEGHSGAVQVVAWNEHHQKLTTSDQYGLIIVWMLYKGSWYEEMINNRNK 98
Query: 314 QEVCGLKWSTDHQLLASGGNDNKLLV 339
V G+KW+ D Q + D ++V
Sbjct: 97 SVVRGMKWTADGQKICIVYEDGAVIV 20
>17807
Length = 484
Score = 29.6 bits (65), Expect = 2.9, Method: Compositional matrix adjust.
Identities = 20/74 (27%), Positives = 32/74 (43%)
Frame = -2
Query: 200 VLSVGLGTCVYLWSACTSQVTRLCDLSVEGDSVTSVGWSERGNLVAVGTHKGFVQIWDAA 259
LS L + LW+ +VT +LS + +T+ + G L VGT+ G +
Sbjct: 414 FLSGSLDGKIRLWNIPDKKVTMWNELSGSSNLITTASFCHNGRLAVVGTYDGRCIFYTTD 235
Query: 260 AGKKLSMLEGHTAR 273
K +ML + R
Sbjct: 234 QLKYYTMLNVRSTR 193
>12841
Length = 1364
Score = 28.9 bits (63), Expect = 5.4, Method: Compositional matrix adjust.
Identities = 21/79 (26%), Positives = 31/79 (39%)
Frame = +1
Query: 181 APELQDDFYLNLVDWSSLNVLSVGLGTCVYLWSACTSQVTRLCDLSVEGDSVTSVGWSER 240
+P + D F DWS + LW + T + +V V WS R
Sbjct: 1075 SPFVSDIFLSCSADWS------------IRLWHQ--DRTTPILTFHSSTKTVHDVCWSPR 1212
Query: 241 GNLVAVGTHKGFVQIWDAA 259
+ V H+G V++WD A
Sbjct: 1213 SSTVFACVHEGAVEVWDLA 1269
>16199
Length = 694
Score = 28.9 bits (63), Expect = 5.4, Method: Compositional matrix adjust.
Identities = 17/63 (26%), Positives = 31/63 (49%), Gaps = 3/63 (4%)
Frame = +2
Query: 221 RLCDLSVEGDSV---TSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGAL 277
++CD S G SV T + G + A GT ++IWD ++ +GH V ++
Sbjct: 44 KVCDKS--GPSVPALTCAQFHPDGLIFATGTEDSVIKIWDLKERANVANFQGHQGPVTSI 217
Query: 278 AWN 280
+++
Sbjct: 218 SFS 226
>30679
Length = 1025
Score = 28.5 bits (62), Expect = 5.9, Method: Compositional matrix adjust.
Identities = 13/61 (21%), Positives = 33/61 (54%), Gaps = 2/61 (3%)
Frame = +1
Query: 255 IWDAAAGKKLSMLEGHTARVGALAWN--AEQLSSGSRDRMILQRDIRTPPLQSERRLQGH 312
+W+ + +++++ HT + +++WN ++ S+D+ + D RT + +E Q H
Sbjct: 40 VWNVEQAEPVNIVDCHTDTIFSMSWNRXGSMFATTSKDKKLRTIDPRTTTVAAES--QCH 213
Query: 313 R 313
+
Sbjct: 214 K 216
>00105
Length = 1426
Score = 28.5 bits (62), Expect = 6.2, Method: Compositional matrix adjust.
Identities = 10/28 (35%), Positives = 16/28 (57%)
Frame = +3
Query: 366 HQHGLLASGGGTADRCIRFWNTLTGQPL 393
H HG+ G + +RC+ L+GQP+
Sbjct: 1131 HNHGVFVGRGYSLERCMVLCGVLSGQPM 1214
>38177
Length = 430
Score = 28.5 bits (62), Expect = 7.1, Method: Compositional matrix adjust.
Identities = 17/71 (23%), Positives = 34/71 (47%), Gaps = 2/71 (2%)
Frame = +3
Query: 319 LKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTA 378
L W+ + + L +G + + +WN + + H +V+A+ WS H ++ TA
Sbjct: 6 LAWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDVSVRAMRWSNHDQWMV-----TA 170
Query: 379 DRC--IRFWNT 387
D I++W +
Sbjct: 171 DHSGYIKYWQS 203
>17602
Length = 481
Score = 28.5 bits (62), Expect = 7.1, Method: Compositional matrix adjust.
Identities = 18/67 (26%), Positives = 29/67 (43%), Gaps = 5/67 (7%)
Frame = +3
Query: 232 VTSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWN-----AEQLSS 286
V+ V +S G + T +++WD + GK L GH + N + + S
Sbjct: 192 VSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYVGHRNEKYCIFANFSVTGGKWIVS 371
Query: 287 GSRDRMI 293
GS D M+
Sbjct: 372 GSEDNMV 392
>30297
Length = 822
Score = 28.1 bits (61), Expect = 7.8, Method: Compositional matrix adjust.
Identities = 30/119 (25%), Positives = 44/119 (36%), Gaps = 18/119 (15%)
Frame = -3
Query: 302 PLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWN--------HSSLSPVQQYTE 353
P ++ GH+++V + LLA+ D +++VWN H P YT+
Sbjct: 733 PYWADDERDGHKEDVLAVAHCLP-NLLATASYDGEVIVWNMVSGHIFCHLRPPPPADYTD 557
Query: 354 H----------LAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQV 402
L +K A+ L+ASG I WN G L G QV
Sbjct: 556 QSLDGDLGISKLLFLKTRAYKKDAGSLVASGPRAH---IHIWNVFQGGRLMAQFPGVQV 389
>30108
Length = 1032
Score = 28.1 bits (61), Expect = 9.1, Method: Compositional matrix adjust.
Identities = 43/176 (24%), Positives = 69/176 (39%), Gaps = 13/176 (7%)
Frame = +1
Query: 312 HRQEVCGLKWSTDHQLLASGGNDNKLLV-WNHSSLSPVQQYTEHLAAVKAIAWSPHQHGL 370
H V W A DN + V ++ S+L PV ++ +V +AW P +
Sbjct: 97 HESPVRAFAWHPHTTKFALALQDNSVHVHYSASTLVPVLKHKLQ-KSVAHLAWQPLSASV 273
Query: 371 LASGGGTADRCIRFWN----TLTGQP----LQCIDTGSQ--VCNLAWSKHANELVSTHGY 420
LA +A + W+ +L +P +Q + + +LAW AN L+S
Sbjct: 274 LAVACQSA---VLIWHIEPTSLAARPSSSSVQVLQHSGHCPITHLAWLPSANILLSASPV 444
Query: 421 SQNQILVWKY--PSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFS 474
++ W + T + L G V LA SPDG ++ R W+ S
Sbjct: 445 -DTAVMAWSVGGEACTALRYLGGGG--VSLLACSPDGSKVMAATPATLFRVWDTTS 603
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000221926 | hsapiens_gene_ensembl | Fizzy-related
protein homolog (Fzr) (Cdh1/Hct1 homolog) (hCDH1) (CDC20-like protein
1). [Source:Uniprot/SWISSPROT;Acc:Q9UM11]
(493 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
14500 155 3e-50
34005 124 2e-31
29912 132 3e-31
14884 70 2e-12
00561 58 2e-11
27760 65 9e-11
02147 60 3e-09
01327 57 2e-08
13335 57 2e-08
30256 56 3e-08
19498 55 6e-08
17598 55 7e-08
03156 54 1e-07
27465 51 1e-06
12806 51 1e-06
16389 50 2e-06
03387 50 2e-06
19949 50 2e-06
17266 49 5e-06
16105 48 9e-06
02960 46 3e-05
12574 45 7e-05
01598 45 7e-05
01805 44 1e-04
01249 43 2e-04
15780 42 6e-04
30295 40 0.002
14555 39 0.003
18981 38 0.007
10264 38 0.009
01768 37 0.017
27475 37 0.017
31474 37 0.020
19863 37 0.020
02090 36 0.033
13278 36 0.037
01462 36 0.043
26107 36 0.044
37142 35 0.075
31054 35 0.085
12140 34 0.12
21921 34 0.13
34511 33 0.22
19140 33 0.29
15337 33 0.30
21105 33 0.34
01584 33 0.36
15972 33 0.37
15118 32 0.46
36111 32 0.80
27270 32 0.85
10162 31 0.94
11493 31 1.2
27681 31 1.3
07665 30 1.6
28289 30 2.5
17807 30 2.6
21025 29 4.6
30679 29 5.4
12841 29 5.4
16199 29 5.5
00105 28 6.4
38177 28 6.8
17602 28 7.1
30297 28 7.7
30108 28 9.8
>14500
Length = 1238
Score = 155 bits (393), Expect(2) = 3e-50, Method: Compositional matrix adjust.
Identities = 69/118 (58%), Positives = 89/118 (75%)
Frame = +3
Query: 363 WSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNLAWSKHANELVSTHGYSQ 422
W P Q LLASGGGTADR I FWN TG L +DT SQVC L WSK EL+S+HG++Q
Sbjct: 225 WCPWQPSLLASGGGTADRHIHFWNCNTGTNLSSVDTKSQVCALLWSKEHRELISSHGFAQ 404
Query: 423 NQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKTRSTK 480
NQ+++WKYP++++VA+LTGH+ RVL++AMSPDGE +V+ A DETLR W F+ + K
Sbjct: 405 NQLIIWKYPAMSRVAELTGHTARVLHMAMSPDGETVVSAAADETLRLWKCFTVDKEKK 578
Score = 61.6 bits (148), Expect(2) = 3e-50, Method: Compositional matrix adjust.
Identities = 31/59 (52%), Positives = 39/59 (66%), Gaps = 5/59 (8%)
Frame = +2
Query: 309 LQGHRQEVCGLKWSTDHQLLASGGNDNKLLVW-----NHSSLSPVQQYTEHLAAVKAIA 362
L GH QEVCGL+WS D + LASG NDN L VW +S P+ +++H AAVKA+A
Sbjct: 47 LSGHSQEVCGLRWSPDGKYLASGANDNLLCVWPAQVTGGNSTQPLHTFSQHQAAVKALA 223
Score = 47.0 bits (110), Expect(2) = 2e-06, Method: Compositional matrix adjust.
Identities = 26/79 (32%), Positives = 43/79 (54%), Gaps = 2/79 (2%)
Frame = +3
Query: 313 RQEVCGLKWSTDHQLLAS--GGNDNKLLVWNHSSLSPVQQYTEHLAAVKAIAWSPHQHGL 370
+ +VC L WS +H+ L S G N+L++W + ++S V + T H A V +A SP +
Sbjct: 333 KSQVCALLWSKEHRELISSHGFAQNQLIIWKYPAMSRVAELTGHTARVLHMAMSPDGETV 512
Query: 371 LASGGGTADRCIRFWNTLT 389
+++ AD +R W T
Sbjct: 513 VSAA---ADETLRLWKCFT 560
Score = 22.3 bits (46), Expect(2) = 2e-06, Method: Compositional matrix adjust.
Identities = 17/59 (28%), Positives = 24/59 (40%), Gaps = 5/59 (8%)
Frame = +2
Query: 225 LSVEGDSVTSVGWSERGNLVAVGTHKGFVQIWDAA-----AGKKLSMLEGHTARVGALA 278
LS V + WS G +A G + + +W A + + L H A V ALA
Sbjct: 47 LSGHSQEVCGLRWSPDGKYLASGANDNLLCVWPAQVTGGNSTQPLHTFSQHQAAVKALA 223
Score = 35.0 bits (79), Expect = 0.074, Method: Compositional matrix adjust.
Identities = 20/67 (29%), Positives = 34/67 (50%), Gaps = 13/67 (19%)
Frame = +2
Query: 435 QVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFW-------------NVFSKTRSTKE 481
V L+GHS V L SPDG+ + +GA D L W + FS+ ++ +
Sbjct: 35 HVGTLSGHSQEVCGLRWSPDGKYLASGANDNLLCVWPAQVTGGNSTQPLHTFSQHQAAVK 214
Query: 482 SVSVLNL 488
+++V++L
Sbjct: 215 ALAVVSL 235
>34005
Length = 456
Score = 124 bits (311), Expect(2) = 2e-31, Method: Compositional matrix adjust.
Identities = 62/114 (54%), Positives = 76/114 (66%), Gaps = 3/114 (2%)
Frame = +1
Query: 314 QEVCGLKWSTDHQLLASGGNDNKLLVWNHS---SLSPVQQYTEHLAAVKAIAWSPHQHGL 370
QEVCGL WS D LASG NDN + +W+ + + P+ T H AAVKA+AW P Q +
Sbjct: 115 QEVCGLSWSPDATFLASGSNDNSVNIWDSTLGMDVPPLHTLTSHQAAVKAVAWCPWQTRM 294
Query: 371 LASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNLAWSKHANELVSTHGYSQNQ 424
LA+GGGT DR IRFWNT TG ++ +DT SQVC++ W K ELVS HGY NQ
Sbjct: 295 LATGGGTNDRHIRFWNTNTGACVKAVDTQSQVCSVLWCKEHRELVSGHGYVMNQ 456
Score = 30.0 bits (66), Expect(2) = 2e-31, Method: Compositional matrix adjust.
Identities = 13/25 (52%), Positives = 15/25 (60%)
Frame = +3
Query: 276 ALAWNAEQLSSGSRDRMILQRDIRT 300
LAWN+ LSSGSR I D+R
Sbjct: 3 CLAWNSHILSSGSRSGNIHHHDVRV 77
Score = 40.8 bits (94), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 38/133 (28%), Positives = 51/133 (38%), Gaps = 8/133 (6%)
Frame = +1
Query: 207 TCVYLWSACTSQVTRLCDLSVEGDSVTSVGWSERGNLVAVGTHKGFVQIWDAAAGKK--- 263
T Y W A TR + V + WS +A G++ V IWD+ G
Sbjct: 61 TTTYAWRA-----TRWGFCPLTPQEVCGLSWSPDATFLASGSNDNSVNIWDSTLGMDVPP 225
Query: 264 LSMLEGHTARVGALAWNAEQ-----LSSGSRDRMILQRDIRTPPLQSERRLQGHRQEVCG 318
L L H A V A+AW Q G+ DR I + T Q +VC
Sbjct: 226 LHTLTSHQAAVKAVAWCPWQTRMLATGGGTNDRHIRFWNTNTGACVKAVDTQ---SQVCS 396
Query: 319 LKWSTDHQLLASG 331
+ W +H+ L SG
Sbjct: 397 VLWCKEHRELVSG 435
Score = 34.3 bits (77), Expect = 0.13, Method: Compositional matrix adjust.
Identities = 27/84 (32%), Positives = 37/84 (44%), Gaps = 6/84 (7%)
Frame = +1
Query: 395 CIDTGSQVCNLAWSKHANELVSTHGYSQNQILVWKYP---SLTQVAKLTGHSYRVLYLAM 451
C T +VC L+WS A L S G + N + +W + + LT H V +A
Sbjct: 100 CPLTPQEVCGLSWSPDATFLAS--GSNDNSVNIWDSTLGMDVPPLHTLTSHQAAVKAVAW 273
Query: 452 SP-DGEAIVTGAG--DETLRFWNV 472
P + TG G D +RFWN
Sbjct: 274 CPWQTRMLATGGGTNDRHIRFWNT 345
>29912
Length = 510
Score = 132 bits (333), Expect = 3e-31, Method: Compositional matrix adjust.
Identities = 72/152 (47%), Positives = 93/152 (61%), Gaps = 5/152 (3%)
Frame = +3
Query: 230 DSVTSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNAEQLSSGSR 289
+ + +V W + GN +A+GT G VQ+WD KKL + GH ARVG+L+WN+ +SSGSR
Sbjct: 12 EYIGAVSWIKEGNYLALGTSTGEVQVWDVTQQKKLRTMAGHAARVGSLSWNSFIVSSGSR 191
Query: 290 DRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVW-----NHSS 344
I D+R L GH QEVCGL+WS D + LASG NDN L VW +S
Sbjct: 192 SGNIHHHDVRVAD-HHVGTLSGHSQEVCGLRWSPDGKYLASGANDNLLCVWPAQVTGGNS 368
Query: 345 LSPVQQYTEHLAAVKAIAWSPHQHGLLASGGG 376
P+ +++H AAVKA+AW P Q LASGGG
Sbjct: 369 TQPLHTFSQHQAAVKALAWCPWQPSXLASGGG 464
Score = 34.3 bits (77), Expect = 0.12, Method: Compositional matrix adjust.
Identities = 16/36 (44%), Positives = 20/36 (55%)
Frame = +3
Query: 435 QVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFW 470
V L+GHS V L SPDG+ + +GA D L W
Sbjct: 234 HVGTLSGHSQEVCGLRWSPDGKYLASGANDNLLCVW 341
Score = 28.9 bits (63), Expect = 4.6, Method: Compositional matrix adjust.
Identities = 24/78 (30%), Positives = 34/78 (43%), Gaps = 8/78 (10%)
Frame = +3
Query: 225 LSVEGDSVTSVGWSERGNLVAVGTHKGFVQIWDAA-----AGKKLSMLEGHTARVGALAW 279
LS V + WS G +A G + + +W A + + L H A V ALAW
Sbjct: 246 LSGHSQEVCGLRWSPDGKYLASGANDNLLCVWPAQVTGGNSTQPLHTFSQHQAAVKALAW 425
Query: 280 NAEQ---LSSGSRDRMIL 294
Q L+SG D +I+
Sbjct: 426 CPWQPSXLASGGGDVLIV 479
>14884
Length = 632
Score = 70.5 bits (171), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 33/79 (41%), Positives = 49/79 (62%)
Frame = -1
Query: 169 RKISKIPFKVLDAPELQDDFYLNLVDWSSLNVLSVGLGTCVYLWSACTSQVTRLCDLSVE 228
R I P VLDAP + DD+YL+ +DWSS N ++ LG VYLW A + +T+L ++ +
Sbjct: 245 RHIPSRPEHVLDAPVVLDDYYLHTIDWSSTNTVAAALGPEVYLWHARDATITQLMRVA-D 69
Query: 229 GDSVTSVGWSERGNLVAVG 247
D ++SV W G ++ VG
Sbjct: 68 SDYISSVSWISDGTVLGVG 12
>00561
Length = 1003
Score = 57.8 bits (138), Expect(2) = 2e-11, Method: Compositional matrix adjust.
Identities = 54/203 (26%), Positives = 95/203 (46%), Gaps = 6/203 (2%)
Frame = -3
Query: 232 VTSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNAE--QLSSGSR 289
++ V S GN G+ +++WD AAGK EGHT V ++A++A+ Q+ SGSR
Sbjct: 857 ISDVVLSSDGNYALSGSWDQTLRLWDLAAGKTTRRFEGHTKDVLSVAFSADNRQIVSGSR 678
Query: 290 DRMILQRDIRTPPLQSERRLQ--GHRQEVCGLKWSTDHQ--LLASGGNDNKLLVWNHSSL 345
D+ I + + + +Q GH V +++S +H ++ S G D + VWN ++
Sbjct: 677 DKTIKLWNTLA---ECKFTIQEDGHTDWVSCVRFSPNHSNPIIVSCGWDRTVKVWNLANC 507
Query: 346 SPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNL 405
+ H + + SP G L + GG + + W+ G+ L ++ + L
Sbjct: 506 KLKNNHHGHNGYLNTVTVSP--DGSLCTSGGKDSKAL-LWDLNDGKNLYTLEHNDIINAL 336
Query: 406 AWSKHANELVSTHGYSQNQILVW 428
+S + L +G S I +W
Sbjct: 335 CFSPNRYWLCVAYGPS---IKIW 276
Score = 28.5 bits (62), Expect(2) = 2e-11, Method: Compositional matrix adjust.
Identities = 12/28 (42%), Positives = 16/28 (57%)
Frame = -2
Query: 445 RVLYLAMSPDGEAIVTGAGDETLRFWNV 472
+ L LA S DG+ + G D T+R W V
Sbjct: 201 QCLSLAWSTDGQTLFAGYSDNTIRVWQV 118
Score = 57.8 bits (138), Expect = 9e-09, Method: Compositional matrix adjust.
Identities = 46/200 (23%), Positives = 88/200 (44%), Gaps = 7/200 (3%)
Frame = -3
Query: 280 NAEQLSSGSRDRMI----LQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDN 335
+ + + S SRD+ + L RD T ++RL GH + + S+D SG D
Sbjct: 977 DPDTIISASRDKTLIVWKLTRDEDTNYGYPQKRLYGHSHFISDVVLSSDGNYALSGSWDQ 798
Query: 336 KLLVWNHSSLSPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQC 395
L +W+ ++ +++ H V ++A+S +++ G+ D+ I+ WNTL
Sbjct: 797 TLRLWDLAAGKTTRRFEGHTKDVLSVAFSADNRQIVS---GSRDKTIKLWNTLAECKFTI 627
Query: 396 IDTGSQ---VCNLAWSKHANELVSTHGYSQNQILVWKYPSLTQVAKLTGHSYRVLYLAMS 452
+ G C H+N ++ + G+ + + VW + GH+ + + +S
Sbjct: 626 QEDGHTDWVSCVRFSPNHSNPIIVSCGWDRT-VKVWNLANCKLKNNHHGHNGYLNTVTVS 450
Query: 453 PDGEAIVTGAGDETLRFWNV 472
PDG +G D W++
Sbjct: 449 PDGSLCTSGGKDSKALLWDL 390
Score = 38.5 bits (88), Expect = 0.007, Method: Compositional matrix adjust.
Identities = 19/60 (31%), Positives = 33/60 (55%), Gaps = 1/60 (1%)
Frame = -3
Query: 421 SQNQIL-VWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKTRST 479
S +Q L +W + + GH+ VL +A S D IV+G+ D+T++ WN ++ + T
Sbjct: 809 SWDQTLRLWDLAAGKTTRRFEGHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTLAECKFT 630
Score = 29.3 bits (64), Expect = 3.8, Method: Compositional matrix adjust.
Identities = 13/34 (38%), Positives = 19/34 (55%)
Frame = -2
Query: 310 QGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHS 343
+ + + L WSTD Q L +G +DN + VW S
Sbjct: 216 KAEQPQCLSLAWSTDGQTLFAGYSDNTIRVWQVS 115
>27760
Length = 525
Score = 64.7 bits (156), Expect = 9e-11, Method: Compositional matrix adjust.
Identities = 31/32 (96%), Positives = 31/32 (96%)
Frame = -2
Query: 462 AGDETLRFWNVFSKTRSTKESVSVLNLFTRIR 493
AGDETLRFWNVFSKTRSTKES SVLNLFTRIR
Sbjct: 524 AGDETLRFWNVFSKTRSTKESKSVLNLFTRIR 429
>02147
Length = 1547
Score = 59.7 bits (143), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 49/230 (21%), Positives = 98/230 (42%), Gaps = 1/230 (0%)
Frame = +2
Query: 244 VAVGTHKGFVQIWDAAAGKKLSML-EGHTARVGALAWNAEQLSSGSRDRMILQRDIRTPP 302
A G +IWDA G++L H + + + L +GS ++++ D+
Sbjct: 218 AATGAADFSAKIWDAEKGEELQTFSHKHIVKSVDFSHDGTALLTGSNEKLLKVFDLVNTD 397
Query: 303 LQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKAIA 362
+ + GH + G + +D + + S +D + +W+ + VQQ T ++
Sbjct: 398 AEP-KSFAGHTSNIKGALFLSDGKRIISASDDKTVRLWSLETCQEVQQLTFDTPPT-SLT 571
Query: 363 WSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNLAWSKHANELVSTHGYSQ 422
SP ++ ++ T + I F+ T + ++ + + + + S H +E G
Sbjct: 572 LSPDKNTIIV----THSQNIAFYQADTLREMKKFEAEAPISSA--SLHQSERFFVAGGED 733
Query: 423 NQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNV 472
++ + Y + ++ GH V + SPDGE +G+ D TLR W
Sbjct: 734 FKMYKFDYETGKEIESFKGHFGPVHCVRFSPDGELYASGSEDGTLRLWQT 883
>01327
Length = 2215
Score = 57.0 bits (136), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 56/243 (23%), Positives = 107/243 (44%), Gaps = 10/243 (4%)
Frame = +3
Query: 243 LVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNA--EQLSSGSRDRMILQRDIRT 300
L G+ V ++D G+ GH + + + A + S SRD+ I + +
Sbjct: 81 LCLSGSKDKSVVLYDYQNGRLEDRWTGHDREITKVCYGASCNGMFSASRDKTI--KMWQR 254
Query: 301 PPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKA 360
S R GH V + +TD+ LL SG DN + +W+ + + ++Q V
Sbjct: 255 GNSHSIRDFIGHDMVVTAIHLNTDNTLLCSGSRDNTVRIWDVETGACLRQNNIPQNLVTD 434
Query: 361 IAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNLAWSKHANE---LVST 417
+ W P H ++ +G D+ +R +++ T ++ T Q ++ A+ L +
Sbjct: 435 VKWLPGSHLIIQAG---EDKEVRIYDSRTLGIVRSF-TKKQYIQMSCDVTADGQFCLTCS 602
Query: 418 HGYSQN--QILVWKYPSLTQVAKLTGHSYRV---LYLAMSPDGEAIVTGAGDETLRFWNV 472
+G+ N + +W+ + + GH + L+L + D I T + D ++R WN+
Sbjct: 603 NGFGGNGCEATLWQLSDGSIQNEFKGHREAIEACLFLPSNQDMTLIATASRDCSVRVWNM 782
Query: 473 FSK 475
F+K
Sbjct: 783 FTK 791
>13335
Length = 863
Score = 57.0 bits (136), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 52/203 (25%), Positives = 90/203 (44%), Gaps = 24/203 (11%)
Frame = +1
Query: 293 ILQRDIRTPPLQSERRLQGHRQ-EVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQY 351
++ D++T ++ E + VC S+ H L SG +D+ + +W ++ V+ Y
Sbjct: 4 VIVWDVKTGSIKGEYQHASKSSIRVCKFSPSSSH--LVSGSDDDTICMWEVATQKLVRSY 177
Query: 352 TEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQP------LQCIDTGSQVCNL 405
H +V A+A+SP+ H L SG D + W+ G + D G C
Sbjct: 178 VGHEDSVMALAYSPNGH-YLVSGSPNGD--LYVWDASFGHCRHLTLRVDAHDLGVTCCEF 348
Query: 406 A---------WSKHANELVSTHGYSQNQILVWKY------PSLTQVAK--LTGHSYRVLY 448
+ S N L++T G N I +W + P +T + L+GHS V+
Sbjct: 349 SPTFGTACAENSSTCNLLLATGG-KDNLIKLWTFSAQVGSPEVTLQCRDILSGHSDLVMA 525
Query: 449 LAMSPDGEAIVTGAGDETLRFWN 471
A SP + +G+ D+++R W+
Sbjct: 526 CAFSPSSALLASGSFDKSVRLWD 594
Score = 44.7 bits (104), Expect = 8e-05, Method: Compositional matrix adjust.
Identities = 61/220 (27%), Positives = 89/220 (40%), Gaps = 25/220 (11%)
Frame = +1
Query: 247 GTHKGFVQIWDAAAGKKLSMLEGHTARVGALAW--NAEQLSSGSRDRMILQRDIRTPPLQ 304
G+ + +W+ A K + GH V ALA+ N L SGS + + D +
Sbjct: 115 GSDDDTICMWEVATQKLVRSYVGHEDSVMALAYSPNGHYLVSGSPNGDLYVWDASFGHCR 294
Query: 305 S-ERRLQGHRQEV------------CGLKWSTDHQLLASGGNDNKLLVWNHS-------- 343
R+ H V C ST + LLA+GG DN + +W S
Sbjct: 295 HLTLRVDAHDLGVTCCEFSPTFGTACAENSSTCNLLLATGGKDNLIKLWTFSAQVGSPEV 474
Query: 344 SLSPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQ-- 401
+L + H V A A+SP LLAS G+ D+ +R W+++ G L I+
Sbjct: 475 TLQCRDILSGHSDLVMACAFSP-SSALLAS--GSFDKSVRLWDSVKGVALFSIEACHSRF 645
Query: 402 VCNLAWSKHANELVSTHGYSQNQILVWKYPSLTQVAKLTG 441
V A+S L S G I +WK LT + + G
Sbjct: 646 VTCCAFSIDGTLLAS--GSMDRIIKIWK---LTDTSSIMG 750
Score = 44.7 bits (104), Expect = 8e-05, Method: Compositional matrix adjust.
Identities = 55/205 (26%), Positives = 91/205 (44%), Gaps = 28/205 (13%)
Frame = +1
Query: 209 VYLWSACTSQVTRLCDLSVEG--DSVTSVGWSERGNLVAVGTHKGFVQIWDAAAG--KKL 264
+ +W T ++ R S G DSV ++ +S G+ + G+ G + +WDA+ G + L
Sbjct: 133 ICMWEVATQKLVR----SYVGHEDSVMALAYSPNGHYLVSGSPNGDLYVWDASFGHCRHL 300
Query: 265 SM-LEGHTARVGALAWN-------AEQ-------LSSGSRDRMI----LQRDIRTP--PL 303
++ ++ H V ++ AE L++G +D +I + +P L
Sbjct: 301 TLRVDAHDLGVTCCEFSPTFGTACAENSSTCNLLLATGGKDNLIKLWTFSAQVGSPEVTL 480
Query: 304 QSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYT---EHLAAVKA 360
Q L GH V +S LLASG D + +W+ S+ V ++ H V
Sbjct: 481 QCRDILSGHSDLVMACAFSPSSALLASGSFDKSVRLWD--SVKGVALFSIEACHSRFVTC 654
Query: 361 IAWSPHQHGLLASGGGTADRCIRFW 385
A+S LLAS G+ DR I+ W
Sbjct: 655 CAFSI-DGTLLAS--GSMDRIIKIW 720
Score = 32.3 bits (72), Expect = 0.46, Method: Compositional matrix adjust.
Identities = 31/118 (26%), Positives = 53/118 (44%), Gaps = 11/118 (9%)
Frame = +1
Query: 243 LVAVGTHKGFVQIWDAAAG--------KKLSMLEGHTARVGALAWN--AEQLSSGSRDRM 292
L+A G +++W +A + +L GH+ V A A++ + L+SGS D+
Sbjct: 400 LLATGGKDNLIKLWTFSAQVGSPEVTLQCRDILSGHSDLVMACAFSPSSALLASGSFDKS 579
Query: 293 I-LQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQ 349
+ L ++ L S H + V +S D LLASG D + +W + S +
Sbjct: 580 VRLWDSVKGVALFSIEAC--HSRFVTCCAFSIDGTLLASGSMDRIIKIWKLTDTSSIM 747
>30256
Length = 961
Score = 55.8 bits (133), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 48/175 (27%), Positives = 78/175 (44%)
Frame = +3
Query: 220 TRLCDLSVEGDSVTSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAW 279
T +C ++ G S T S G V G+ +++WD +G L++L GH A V + +
Sbjct: 129 TGVCTHTLYGHSSTVRCLSLSGKKVVSGSRDATLRVWDIESGHCLNVLLGHMAAVRCVQY 308
Query: 280 NAEQLSSGSRDRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLV 339
+ +++ SG+ D + D T LQGH V L++ D + SG D + V
Sbjct: 309 DGKRVVSGAXDYTVRVWDPDTASCL--HTLQGHTNRVYSLQF--DGVYVVSGSLDTSIRV 476
Query: 340 WNHSSLSPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQ 394
W+ V H + + + LL S G AD ++ W+ TG+ LQ
Sbjct: 477 WDVRCGKLVHTLMGHQSLTSGLELKDN---LLVS--GNADSTVKVWDVHTGKCLQ 626
Score = 46.2 bits (108), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 55/217 (25%), Positives = 85/217 (39%)
Frame = +3
Query: 258 AAAGKKLSMLEGHTARVGALAWNAEQLSSGSRDRMILQRDIRTPPLQSERRLQGHRQEVC 317
A G+ + L GHT V + + SGS DR + + T L GH V
Sbjct: 3 AVTGRCIKNLIGHTGGVWSSQMTGNTVISGSTDRSLKVWNADTGV--CTHTLYGHSSTVR 176
Query: 318 GLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKAIAWSPHQHGLLASGGGT 377
L S + + SG D L VW+ S + H+AAV+ + + + + SG
Sbjct: 177 CL--SLSGKKVVSGSRDATLRVWDIESGHCLNVLLGHMAAVRCVQYDGKR---VVSGA-- 335
Query: 378 ADRCIRFWNTLTGQPLQCIDTGSQVCNLAWSKHANELVSTHGYSQNQILVWKYPSLTQVA 437
D +R W+ T C+ T N +S + + G I VW V
Sbjct: 336 XDYTVRVWDPDTA---SCLHTLQGHTNRVYSLQFDGVYVVSGSLDTSIRVWDVRCGKLVH 506
Query: 438 KLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFS 474
L GH + L + +V+G D T++ W+V +
Sbjct: 507 TLMGH--QSLTSGLELKDNLLVSGNADSTVKVWDVHT 611
>19498
Length = 903
Score = 55.1 bits (131), Expect = 6e-08, Method: Compositional matrix adjust.
Identities = 54/208 (25%), Positives = 77/208 (37%), Gaps = 8/208 (3%)
Frame = -1
Query: 222 LCDLSVEGDSVTSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNA 281
LC + V V WSE G +A G + IW + G G G+
Sbjct: 807 LCQMDSHLGCVNCVRWSENGKFLASGGDDKLIMIWQISRG------FGSGKSFGS----- 661
Query: 282 EQLSSGSRDRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWN 341
+ IL+ +S L+GH +V L WS LAS DN ++VWN
Sbjct: 660 --------NVTILEH------WRSVATLRGHAGDVLDLAWSPQDLWLASCSVDNTIVVWN 523
Query: 342 HSSLSP-VQQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGS 400
S V H VK + W P L + + D+ +R W T + C+ +
Sbjct: 522 ALKFSEQVAVIRGHAGMVKGVTWDPVGRYLASQ---SDDKTLRVWRTSDWKEETCVKSCF 352
Query: 401 QVCN-------LAWSKHANELVSTHGYS 421
+ C L WS N +VS H +
Sbjct: 351 KECGGTTHVLRLNWSPDGNHVVSAHAMN 268
Score = 44.7 bits (104), Expect = 8e-05, Method: Compositional matrix adjust.
Identities = 50/192 (26%), Positives = 76/192 (39%), Gaps = 34/192 (17%)
Frame = -1
Query: 332 GNDNKLLVWNHSSLSPVQ---------------QYTEHLAAVKAIAWSPHQHGLLASGGG 376
G+ K+++WN ++P++ Q HL V + WS + LASGG
Sbjct: 891 GDSGKVVIWN---MAPIRDEKEEADDDVPRVLCQMDSHLGCVNCVRWSENGK-FLASGGD 724
Query: 377 TADRCIRFWNTLTG--------------QPLQCIDT----GSQVCNLAWSKHANELVSTH 418
D+ I W G + + + T V +LAWS L S
Sbjct: 723 --DKLIMIWQISRGFGSGKSFGSNVTILEHWRSVATLRGHAGDVLDLAWSPQDLWLASCS 550
Query: 419 GYSQNQILVWKYPSLT-QVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKTR 477
N I+VW + QVA + GH+ V + P G + + + D+TLR W +T
Sbjct: 549 --VDNTIVVWNALKFSEQVAVIRGHAGMVKGVTWDPVGRYLASQSDDKTLRVW----RTS 388
Query: 478 STKESVSVLNLF 489
KE V + F
Sbjct: 387 DWKEETCVKSCF 352
>17598
Length = 875
Score = 55.1 bits (131), Expect = 7e-08, Method: Compositional matrix adjust.
Identities = 48/202 (23%), Positives = 88/202 (43%), Gaps = 11/202 (5%)
Frame = +1
Query: 282 EQLSSGSRDRMILQRDI--RTPPLQSE------RRLQGHRQEVCGLKWSTDHQLLASGGN 333
E L G RD++++ D+ R + E R LQGH V + S D + + S
Sbjct: 4 EFLIXGGRDKLLIVWDLVPRKDGDEDETWGGPRRTLQGHSHFVSDVSLSADSRYVLSSSW 183
Query: 334 DNKLLVWNHSSLSPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPL 393
D L +W+ + +++ H A+A+SP +ASGG D+ ++ WNT+ G+
Sbjct: 184 DATLRLWDIKKGNTTRRFISHTRDALAVAFSPDNRQ-IASGG--RDKALKIWNTV-GECK 351
Query: 394 QCIDTGSQ---VCNLAWSKHANELVSTHGYSQNQILVWKYPSLTQVAKLTGHSYRVLYLA 450
+D S V + + + A + I VW ++T GH ++ +
Sbjct: 352 FTVDANSHQDWVTCVKFHQDAKSPLVVSASMDKTIKVWDNQTMTLKHTFVGHKTQINAID 531
Query: 451 MSPDGEAIVTGAGDETLRFWNV 472
++ + +G+ D + WN+
Sbjct: 532 LALKTYYLASGSKDGIVMTWNI 597
Score = 39.7 bits (91), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 45/212 (21%), Positives = 87/212 (41%), Gaps = 4/212 (1%)
Frame = +1
Query: 232 VTSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNAE--QLSSGSR 289
V+ V S V + +++WD G HT A+A++ + Q++SG R
Sbjct: 130 VSDVSLSADSRYVLSSSWDATLRLWDIKKGNTTRRFISHTRDALAVAFSPDNRQIASGGR 309
Query: 290 DRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQ--LLASGGNDNKLLVWNHSSLSP 347
D+ + + + H+ V +K+ D + L+ S D + VW++ +++
Sbjct: 310 DKALKIWNT-VGECKFTVDANSHQDWVTCVKFHQDAKSPLVVSASMDKTIKVWDNQTMTL 486
Query: 348 VQQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNLAW 407
+ H + AI + + L G+ D + WN G L ID +V + +
Sbjct: 487 KHTFVGHKTQINAIDLALKTYYL---ASGSKDGIVMTWNIQNGTFLGKIDCDCEVNAVKF 657
Query: 408 SKHANELVSTHGYSQNQILVWKYPSLTQVAKL 439
S + L G S+ I +W P+ ++ +
Sbjct: 658 SPNKYWLFV--GTSEG-IQIWDLPNQKKIKDI 744
Score = 34.3 bits (77), Expect = 0.12, Method: Compositional matrix adjust.
Identities = 16/67 (23%), Positives = 30/67 (44%)
Frame = +1
Query: 427 VWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKTRSTKESVSVL 486
+W + H+ L +A SPD I +G D+ L+ WN + + T ++ S
Sbjct: 199 LWDIKKGNTTRRFISHTRDALAVAFSPDNRQIASGGRDKALKIWNTVGECKFTVDANSHQ 378
Query: 487 NLFTRIR 493
+ T ++
Sbjct: 379 DWVTCVK 399
>03156
Length = 1014
Score = 53.9 bits (128), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 51/217 (23%), Positives = 98/217 (45%), Gaps = 10/217 (4%)
Frame = +1
Query: 269 GHTARVGALAWNA--EQLSSGSRDRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQ 326
GH + + + A + S SRD+ I + + S R GH V + +TD+
Sbjct: 49 GHDREITKVCYGASCNGMFSASRDKTI--KMWQRGNSHSIRDFIGHDMVVTAIHLNTDNT 222
Query: 327 LLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWN 386
LL SG DN + +W+ + + ++Q V + W P H ++ +G D+ +R ++
Sbjct: 223 LLCSGSRDNTVRIWDVETGACLRQNNIPQNLVTDVKWLPGSHLIIQAG---EDKEVRIYD 393
Query: 387 TLTGQPLQCIDTGSQVCNLAWSKHANE---LVSTHGYSQN--QILVWKYPSLTQVAKLTG 441
+ T ++ T Q ++ A+ L ++G+ N + +W+ + + G
Sbjct: 394 SRTLGIVRSF-TKKQYIQMSCDVTADGQFCLTCSNGFGGNGCEATLWQLSDGSIQNEFKG 570
Query: 442 HSYRV---LYLAMSPDGEAIVTGAGDETLRFWNVFSK 475
H + L+L + D I T + D ++R WN+F+K
Sbjct: 571 HREAIEACLFLPSNQDMTLIATASRDCSVRVWNMFTK 681
>27465
Length = 658
Score = 51.2 bits (121), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 30/113 (26%), Positives = 60/113 (53%), Gaps = 3/113 (2%)
Frame = -1
Query: 232 VTSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWN---AEQLSSGS 288
+T+V +++ G+ G++ +IWD A+ ++L LEGH V A+A+N +++ +GS
Sbjct: 352 LTNVAFNKSGSSFITGSYDRTCKIWDTASAEELHTLEGHRNVVYAIAFNNPFGDKVITGS 173
Query: 289 RDRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWN 341
D+ + T + L+GH E+ + ++ L+A+G D +W+
Sbjct: 172 FDKTC--KLWSTADGKCYHTLRGHTAEIVCVSFNPSSTLIATGSMDTTCRLWD 20
Score = 38.5 bits (88), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 24/98 (24%), Positives = 45/98 (45%), Gaps = 1/98 (1%)
Frame = -1
Query: 376 GTADRCIRFWNTLTGQPLQCIDTGSQVC-NLAWSKHANELVSTHGYSQNQILVWKYPSLT 434
G+ DR + W+T + + L ++ V +A++ + V T + + L W
Sbjct: 307 GSYDRTCKIWDTASAEELHTLEGHRNVVYAIAFNNPFGDKVITGSFDKTCKL-WSTADGK 131
Query: 435 QVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNV 472
L GH+ ++ ++ +P I TG+ D T R W+V
Sbjct: 130 CYHTLRGHTAEIVCVSFNPSSTLIATGSMDTTCRLWDV 17
>12806
Length = 961
Score = 50.8 bits (120), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 49/200 (24%), Positives = 81/200 (40%), Gaps = 11/200 (5%)
Frame = +3
Query: 284 LSSGSRDRMILQRDIRTPPLQSE--------RRLQGHRQEVCGLKWSTDHQLLASGGNDN 335
L SG RD I+ D+ E + L GH + L S D + S D
Sbjct: 54 LISGGRDNNIIVWDL*PKKDGDEDQTWGVPRKTLTGHSHFISDLALSADSRFALSSSWDA 233
Query: 336 KLLVWNHSSLSPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQC 395
L +W+ S ++ H V +A+SP +ASGG D+ ++ WN + G+
Sbjct: 234 TLRLWDIKKGSTTSRFINHTRDVLTVAFSPDNRQ-IASGG--RDKNLKIWNIM-GECKYT 401
Query: 396 IDTGSQ---VCNLAWSKHANELVSTHGYSQNQILVWKYPSLTQVAKLTGHSYRVLYLAMS 452
+D + V + + + + + I VW ++T GH ++ L MS
Sbjct: 402 VDANAHTDWVTCVRFHQDTKNPIVVSASNDKTIKVWDNHTMTLKNTFVGHKAQITALDMS 581
Query: 453 PDGEAIVTGAGDETLRFWNV 472
+ +V+G+ D WNV
Sbjct: 582 TN--YLVSGSKDGIAMTWNV 635
Score = 44.7 bits (104), Expect = 8e-05, Method: Compositional matrix adjust.
Identities = 44/192 (22%), Positives = 85/192 (44%), Gaps = 5/192 (2%)
Frame = +3
Query: 253 VQIWDAAAGKKLSMLEGHTARVGALAWNAE--QLSSGSRDRMILQRDIRTPPLQSERRLQ 310
+++WD G S HT V +A++ + Q++SG RD+ + +I +
Sbjct: 237 LRLWDIKKGSTTSRFINHTRDVLTVAFSPDNRQIASGGRDKNLKIWNI-MGECKYTVDAN 413
Query: 311 GHRQEVCGLKWSTDHQ--LLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKAIAWSPHQH 368
H V +++ D + ++ S ND + VW++ +++ + H A + A+ S +
Sbjct: 414 AHTDWVTCVRFHQDTKNPIVVSASNDKTIKVWDNHTMTLKNTFVGHKAQITALDMSTN-- 587
Query: 369 GLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNLAWSKHAN-ELVSTHGYSQNQILV 427
L S G+ D WN G + ID Q+ + ++ N + V +QN I +
Sbjct: 588 -YLVS--GSKDGIAMTWNVAEGSFVGKIDCDDQINAIKFNIENNKKKVWLFIGTQNGIQI 758
Query: 428 WKYPSLTQVAKL 439
W Y ++ +L
Sbjct: 759 WDYSGEKKIKEL 794
Score = 40.0 bits (92), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 17/67 (25%), Positives = 34/67 (50%)
Frame = +3
Query: 427 VWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKTRSTKESVSVL 486
+W + ++ H+ VL +A SPD I +G D+ L+ WN+ + + T ++ +
Sbjct: 243 LWDIKKGSTTSRFINHTRDVLTVAFSPDNRQIASGGRDKNLKIWNIMGECKYTVDANAHT 422
Query: 487 NLFTRIR 493
+ T +R
Sbjct: 423 DWVTCVR 443
Score = 35.0 bits (79), Expect = 0.064, Method: Compositional matrix adjust.
Identities = 25/77 (32%), Positives = 39/77 (50%), Gaps = 2/77 (2%)
Frame = +3
Query: 267 LEGHTARVGALAWNAEQ--LSSGSRDRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTD 324
L GH+ + LA +A+ S S D + DI+ S R H ++V + +S D
Sbjct: 153 LTGHSHFISDLALSADSRFALSSSWDATLRLWDIKKGSTTS--RFINHTRDVLTVAFSPD 326
Query: 325 HQLLASGGNDNKLLVWN 341
++ +ASGG D L +WN
Sbjct: 327 NRQIASGGRDKNLKIWN 377
Score = 28.9 bits (63), Expect = 4.7, Method: Compositional matrix adjust.
Identities = 21/92 (22%), Positives = 39/92 (42%), Gaps = 2/92 (2%)
Frame = +3
Query: 205 LGTCVYLWSACTSQVTRLCDLSVEGDSVTSVGWSE--RGNLVAVGTHKGFVQIWDAAAGK 262
+G C Y D + D VT V + + + +V ++ +++WD
Sbjct: 381 MGECKYT-----------VDANAHTDWVTCVRFHQDTKNPIVVSASNDKTIKVWDNHTMT 527
Query: 263 KLSMLEGHTARVGALAWNAEQLSSGSRDRMIL 294
+ GH A++ AL + L SGS+D + +
Sbjct: 528 LKNTFVGHKAQITALDMSTNYLVSGSKDGIAM 623
>16389
Length = 558
Score = 50.4 bits (119), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 24/27 (88%), Positives = 25/27 (92%)
Frame = -3
Query: 467 LRFWNVFSKTRSTKESVSVLNLFTRIR 493
LRFWNVF +TRSTKES SVLNLFTRIR
Sbjct: 544 LRFWNVFRQTRSTKESKSVLNLFTRIR 464
>03387
Length = 1891
Score = 50.1 bits (118), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 55/256 (21%), Positives = 105/256 (41%), Gaps = 21/256 (8%)
Frame = +1
Query: 238 SERGNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNAEQLSSGSRDRMILQRD 297
SE+G G+ G ++I K++ EG R + N +++ + +L D
Sbjct: 130 SEKGEFGGFGSVSGKIEI-----EIKINH-EGEVNRARYMPQNPCIIATKTPSSDVLVFD 291
Query: 298 IRTPPLQS--------ERRLQGHRQEVCGLKWSTD-HQLLASGGNDNKLLVWNHSS---- 344
P + E RL+GH++E GL W+ + + L S +D+ + +W+ +S
Sbjct: 292 YTKHPSKPDPSGECIPELRLKGHQKEGYGLSWNPNLNGHLLSASDDHTICLWDINSTQRE 471
Query: 345 ---LSPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNT---LTGQPLQCIDT 398
+ +T H + V+ +AW L G D+ + W+T T +P +D
Sbjct: 472 SRVVDAHTIFTGHTSVVEDVAWHLLHESLF--GSVADDQKLMIWDTRSNTTSKPSHVVDA 645
Query: 399 GSQVCNLAWSKHANELVSTHGYSQNQILVWKYPSLT-QVAKLTGHSYRVLYLAMSPDGEA 457
+ N +E + G + + +W +L ++ H + + SP E
Sbjct: 646 HTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNET 825
Query: 458 IVTGAG-DETLRFWNV 472
I+ +G D L W++
Sbjct: 826 ILASSGTDRRLHVWDL 873
Score = 49.3 bits (116), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 38/154 (24%), Positives = 72/154 (46%), Gaps = 21/154 (13%)
Frame = +1
Query: 253 VQIWDA---AAGKKLSMLEGHTARVGALAWNAEQ---LSSGSRDRMILQRDIRTPPLQSE 306
+ IWD K +++ HTA V L++N L++GS D+ + D+R L+
Sbjct: 586 LMIWDTRSNTTSKPSHVVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKL- 762
Query: 307 RRLQGHRQEVCGLKWSTDHQ-LLASGGNDNKLLVWNHSSLSPVQQ--------------Y 351
+ H+ E+ ++WS ++ +LAS G D +L VW+ S + Q +
Sbjct: 763 HSFESHKDEIFQVQWSPHNETILASSGTDRRLHVWDLSKIGEEQLPEDAEDGPPELLFIH 942
Query: 352 TEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFW 385
H A + +W+P++ ++ S + D ++ W
Sbjct: 943 GGHTAKISDFSWNPNEPWIVCS--VSEDNIMQVW 1038
>19949
Length = 903
Score = 49.7 bits (117), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 36/107 (33%), Positives = 55/107 (51%)
Frame = +2
Query: 285 SSGSRDRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSS 344
+SGS D + DIR +GH VC L++S D + +AS D + +W+ ++
Sbjct: 41 ASGSMDCNVKLWDIRRKGCI--YTYKGHTGCVCCLRFSPDGRWIASASEDGLVKLWDLTA 214
Query: 345 LSPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQ 391
+ H AV I + PH+ LLAS G+ADR ++FW+ T Q
Sbjct: 215 GKLLTDLKLHRDAVNTIEFHPHEF-LLAS--GSADRTVKFWDLETFQ 346
Score = 49.3 bits (116), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 46/198 (23%), Positives = 85/198 (42%), Gaps = 6/198 (3%)
Frame = +2
Query: 232 VTSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNAEQ--LSSGSR 289
V S+ + G A G+ V++WD + +GHT V L ++ + ++S S
Sbjct: 2 VKSLDFHPYGAYTASGSMDCNVKLWDIRRKGCIYTYKGHTGCVCCLRFSPDGRWIASASE 181
Query: 290 DRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQ 349
D ++ D+ L ++ +L HR V +++ LLASG D + W+ + +
Sbjct: 182 DGLVKLWDLTAGKLLTDLKL--HRDAVNTIEFHPHEFLLASGSADRTVKFWDLETFQLIS 355
Query: 350 QYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGS----QVCNL 405
++++I + P G+ G + W +PL+ DT S QVC++
Sbjct: 356 TTEPEANSIRSILFHP--DGVCLYSGSKDTLKVYHW-----EPLELYDTVSVPWGQVCDM 514
Query: 406 AWSKHANELVSTHGYSQN 423
+ S +L+ Y N
Sbjct: 515 SISN--TQLIGASFYKTN 562
>17266
Length = 480
Score = 48.9 bits (115), Expect = 5e-06, Method: Composition-based stats.
Identities = 41/163 (25%), Positives = 67/163 (41%), Gaps = 7/163 (4%)
Frame = -1
Query: 312 HRQEVCG----LKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKAIAWSPHQ 367
H Q G L + D + SG D +W+ Q ++ H + + AI + P+
Sbjct: 474 HSQATLGT**VLSLAPDMRTFVSGACDASAKLWDVRDGMCKQTFSGHESDINAITYFPNG 295
Query: 368 HGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVC---NLAWSKHANELVSTHGYSQNQ 424
H A G+ D R ++ Q + + +C ++A+SK L+ GY
Sbjct: 294 H---AFATGSDDATCRLFDIRADQEIGMYSHDNIICGITSVAFSKSGRLLLG--GYDDFN 130
Query: 425 ILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETL 467
+W + L GH RV L ++ DG A+ TG+ D L
Sbjct: 129 CNIWDVLKQERTGVLAGHDNRVSCLGVTEDGSAVATGSWDSFL 1
Score = 32.0 bits (71), Expect = 0.51, Method: Composition-based stats.
Identities = 19/64 (29%), Positives = 31/64 (48%), Gaps = 2/64 (3%)
Frame = -1
Query: 232 VTSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAW--NAEQLSSGSR 289
+TSV +S+ G L+ G IWD ++ +L GH RV L + +++GS
Sbjct: 192 ITSVAFSKSGRLLLGGYDDFNCNIWDVLKQERTGVLAGHDNRVSCLGVTEDGSAVATGSW 13
Query: 290 DRMI 293
D +
Sbjct: 12 DSFL 1
>16105
Length = 960
Score = 47.8 bits (112), Expect = 9e-06, Method: Compositional matrix adjust.
Identities = 33/117 (28%), Positives = 53/117 (45%), Gaps = 8/117 (6%)
Frame = -2
Query: 309 LQGHRQEVCGLKWST-DHQLLASGGNDNKLLVWN--HSSL-----SPVQQYTEHLAAVKA 360
+ GH+ V ++W + ++AS +D + VW S L PV H
Sbjct: 587 VAGHKGAVLDIQWCPHNDNVIASASDDCTVKVWQIPDSGLVTNLTDPVVDLVGHQKRCCL 408
Query: 361 IAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNLAWSKHANELVST 417
I W P +L S G AD I FWN TG+P+ +D + ++++ + + LV T
Sbjct: 407 IVWHPSAQNVLVSAG--ADNKILFWNVGTGEPMLEVDVPDMIYCMSFNFNGSRLVCT 243
>02960
Length = 1577
Score = 46.2 bits (108), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 67/281 (23%), Positives = 117/281 (41%), Gaps = 40/281 (14%)
Frame = +2
Query: 247 GTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNAEQLSS-------GSRDR--MILQRD 297
G++ V++W + G+ + + GHT+ V +AW SS GS D+ ++ Q
Sbjct: 533 GSYDNTVRLW-STKGEAIMTIPGHTSPVKCVAWIKHDESSGVSTFVTGSHDQTALVWQWQ 709
Query: 298 IRTPPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHS-------------- 343
T + +GH V + S D Q + +G D L +W+
Sbjct: 710 RETNEVDCRLSCRGHAASVDCVAVSPDSQQMCTGSWDKMLKLWSTDCNVDGDQSEDTERP 889
Query: 344 ------------SLSPVQQYTEHLAAVKAIAW-SPHQHGLLASGGGTADRCIRFWNTLTG 390
+ PV + H AV A+ W PH+ ++ S + D +R W+ T
Sbjct: 890 SKKKKSAKSTTQTRVPVLTLSGHAEAVSAVRWLDPHR--VVTS---SWDHSLRLWDLHTA 1054
Query: 391 QPLQCIDTGSQVCNLAWSKHANELVSTHGYSQNQI-LVWKYPSLTQVAK--LTGHSYRVL 447
Q I V ++A+S ++ L++ G + + LV S + K T H+ V
Sbjct: 1055QQTSLIQGSKAVLDVAYSPLSHMLIT--GSADRHVRLVDPRCSEGETVKCAFTSHTGWVT 1228
Query: 448 YLAMSPDGEAI-VTGAGDETLRFWNVFSKTRSTKESVSVLN 487
+ SP E + ++G+ D L+ W+ TRS K ++ +N
Sbjct: 1229GVDWSPTREHLFLSGSYDNVLKLWD----TRSPKATLYDMN 1339
Score = 38.9 bits (89), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 40/141 (28%), Positives = 68/141 (48%), Gaps = 7/141 (4%)
Frame = +2
Query: 211 LWSACTSQVTRLCDLSVEGD-SVTSVGWSERGNLVAVGTHKGFVQIWD--AAAGKKLSM- 266
LW T+Q T L ++G +V V +S +++ G+ V++ D + G+ +
Sbjct: 1034 LWDLHTAQQTSL----IQGSKAVLDVAYSPLSHMLITGSADRHVRLVDPRCSEGETVKCA 1201
Query: 267 LEGHTARVGALAWNAEQ---LSSGSRDRMILQRDIRTPPLQSERRLQGHRQEVCGLKWST 323
HT V + W+ + SGS D ++ D R+P + + H + + WS
Sbjct: 1202 FTSHTGWVTGVDWSPTREHLFLSGSYDNVLKLWDTRSPK-ATLYDMNWHEDRILAVDWSI 1378
Query: 324 DHQLLASGGNDNKLLVWNHSS 344
+LL SGG DNKL V+++SS
Sbjct: 1379 P-ELLLSGGVDNKLHVFSYSS 1438
>12574
Length = 521
Score = 45.1 bits (105), Expect = 7e-05, Method: Compositional matrix adjust.
Identities = 31/110 (28%), Positives = 55/110 (50%), Gaps = 2/110 (1%)
Frame = +3
Query: 267 LEGHTARVGALAW--NAEQLSSGSRDRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTD 324
L GHT + A+ + N + L+S S D++I + + E+ + GH+ + + WS+D
Sbjct: 174 LAGHTKALSAVKFSPNGDWLASSSADKLI--KIWGAYDGKFEKTIAGHKLGLSDVAWSSD 347
Query: 325 HQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKAIAWSPHQHGLLASG 374
+LL S +D L +W S+ ++ H V ++P Q L+ SG
Sbjct: 348 SKLLCSASDDKTLKIWEFSTGKCMKTLKGHSNYVFCCNFNP-QSNLIVSG 494
Score = 38.1 bits (87), Expect = 0.008, Method: Compositional matrix adjust.
Identities = 31/112 (27%), Positives = 56/112 (50%), Gaps = 3/112 (2%)
Frame = +3
Query: 354 HLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQV--CNLAWSKHA 411
H A+ A+ +SP+ L +S +AD+ I+ W G+ + I G ++ ++AWS +
Sbjct: 183 HTKALSAVKFSPNGDWLASS---SADKLIKIWGAYDGKFEKTI-AGHKLGLSDVAWSSDS 350
Query: 412 NELVSTHGYSQNQIL-VWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGA 462
L S S ++ L +W++ + + L GHS V +P IV+G+
Sbjct: 351 KLLCSA---SDDKTLKIWEFSTGKCMKTLKGHSNYVFCCNFNPQSNLIVSGS 497
Score = 37.0 bits (84), Expect = 0.020, Method: Compositional matrix adjust.
Identities = 25/103 (24%), Positives = 50/103 (48%), Gaps = 2/103 (1%)
Frame = +3
Query: 231 SVTSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNAEQ--LSSGS 288
++++V +S G+ +A + ++IW A GK + GH + +AW+++ L S S
Sbjct: 192 ALSAVKFSPNGDWLASSSADKLIKIWGAYDGKFEKTIAGHKLGLSDVAWSSDSKLLCSAS 371
Query: 289 RDRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQLLASG 331
D+ + + T + + L+GH V ++ L+ SG
Sbjct: 372 DDKTLKIWEFSTG--KCMKTLKGHSNYVFCCNFNPQSNLIVSG 494
Score = 28.9 bits (63), Expect = 5.3, Method: Compositional matrix adjust.
Identities = 10/43 (23%), Positives = 23/43 (53%)
Frame = +3
Query: 431 PSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVF 473
P+ T L GH+ + + SP+G+ + + + D+ ++ W +
Sbjct: 150 PTYTLKFTLAGHTKALSAVKFSPNGDWLASSSADKLIKIWGAY 278
>01598
Length = 1545
Score = 45.1 bits (105), Expect = 7e-05, Method: Compositional matrix adjust.
Identities = 43/185 (23%), Positives = 72/185 (38%), Gaps = 26/185 (14%)
Frame = +1
Query: 227 VEGDSVTSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWN------ 280
V+G T + WS N AVGT +G V + K ++ + + + W+
Sbjct: 967 VKGLKATELSWSPDQNAAAVGTDEGSVYVVTIQDLKIVAAIRTQQKLINCVRWHPRLTDQ 1146
Query: 281 -------AEQLSSGSRDRMILQRDIRTP------------PLQSERRLQGHRQEVCGLKW 321
L++ D++I D+ + L S R L GH Q V + W
Sbjct: 1147 SPAGSPCCHWLAAAGNDQVIHVVDLASVFAEREGDKETSLILTSLRELSGHSQRVTDMSW 1326
Query: 322 STDHQL-LASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTADR 380
S H L S G D + VW+ + + Q+ H+ + +S L+ +GG +D
Sbjct: 1327 SPHHDARLVSVGYDAEAFVWDVQKGTALAQFKGHMGRLLTCQFSGLDPDLVMTGG--SDA 1500
Query: 381 CIRFW 385
+ W
Sbjct: 1501 SVHVW 1515
>01805
Length = 2124
Score = 44.3 bits (103), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 57/261 (21%), Positives = 104/261 (39%), Gaps = 20/261 (7%)
Frame = -1
Query: 241 GNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNAEQLSSGSRDRMILQRDIRT 300
GN VA+G+ + ++IWD L ++E VG L+ GS+ +
Sbjct: 726 GNFVAIGSMEPVIEIWD------LDIMES----VGP------TLTLGSKPKK------TK 613
Query: 301 PPLQSERRLQGHRQEVCGLKWSTD-HQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVK 359
++ + + GH Q V L W+ + +LAS D + +W+ S +T+H V+
Sbjct: 612 KKMKQKESVTGHTQAVLDLSWNRNARHVLASASADTTVALWDLSEGKMAMNFTQHSREVQ 433
Query: 360 AIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNLAWS----------K 409
W P + L +G F NT+ + + C ++ C+ +W+
Sbjct: 432 CCNWHPQEEQTLLTGS--------FDNTV--KVVDC--RSAETCHKSWTVEGEVEKAVWN 289
Query: 410 HANELVSTHGYSQNQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAI-VTGAGDETLR 468
H N L + + + V + HS V + +S + +T + D+T++
Sbjct: 288 HHNPLQLLACTDKGMVYCFDIRHEKPVFSVGAHSSCVTGVCLSSQIPGLMITTSEDKTMK 109
Query: 469 FWN--------VFSKTRSTKE 481
W+ VFS+ KE
Sbjct: 108 VWDIQDDKPTHVFSRNLKMKE 46
>01249
Length = 1743
Score = 43.1 bits (100), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 38/124 (30%), Positives = 55/124 (44%), Gaps = 14/124 (11%)
Frame = -1
Query: 235 VGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNAEQ--LSSGSRDRM 292
VG VA + G ++WD +G L + T VG L + ++ L +G +
Sbjct: 1188 VGCGGPAARVASSSSDGTCKLWDMLSGALLRTMVYETG-VGCLIMDKQEHFLLAGLDNGD 1012
Query: 293 ILQRDIRTPPLQSE------------RRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVW 340
IL + QSE R LQGH V L +S+D Q LASG + K+++W
Sbjct: 1011 ILCSPLFGQISQSEVFVSKHTTKAGERVLQGHSDAVTCLAFSSDGQRLASGSQNGKVIIW 832
Query: 341 NHSS 344
N S
Sbjct: 831 NMES 820
Score = 36.2 bits (82), Expect = 0.027, Method: Compositional matrix adjust.
Identities = 53/269 (19%), Positives = 95/269 (35%), Gaps = 3/269 (1%)
Frame = -1
Query: 209 VYLWSACT-SQVTRLCDLSVEGDSVTSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSML 267
+Y+W S V L D + T + +++ G+ V T G + IWD A
Sbjct: 1422 IYIWEMTGGSLVGLLSDF----NEATKIQFTDDGSQFVVATSSGHLNIWDFA-------- 1279
Query: 268 EGHTARVGALAWNAEQLSSGSRDRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQL 327
R++ R L+ R + H + + GL
Sbjct: 1278 -----------------------RVVTTTSQRARGLKPGRTINAHSEPITGLHVGCGGPA 1168
Query: 328 --LASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFW 385
+AS +D +W+ S + ++ + V + +H LLA
Sbjct: 1167 ARVASSSSDGTCKLWDMLSGALLRTMV-YETGVGCLIMDKQEHFLLAG------------ 1027
Query: 386 NTLTGQPLQCIDTGSQVCNLAWSKHANELVSTHGYSQNQILVWKYPSLTQVAKLTGHSYR 445
+D G +C+ + + SQ+++ V K+ + L GHS
Sbjct: 1026 ----------LDNGDILCSPLFGQ----------ISQSEVFVSKHTTKAGERVLQGHSDA 907
Query: 446 VLYLAMSPDGEAIVTGAGDETLRFWNVFS 474
V LA S DG+ + +G+ + + WN+ S
Sbjct: 906 VTCLAFSSDGQRLASGSQNGKVIIWNMES 820
>15780
Length = 735
Score = 42.0 bits (97), Expect = 6e-04, Method: Compositional matrix adjust.
Identities = 21/60 (35%), Positives = 34/60 (56%)
Frame = -1
Query: 413 ELVSTHGYSQNQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNV 472
+ +ST G + + ++VW S T VA LT H+ V L S DG + +G D ++R W++
Sbjct: 735 KYLSTAG-ADHTVIVWDIASGTAVAHLTAHTDTVYALCFSRDGTVLASGGMDNSIRLWDL 559
Score = 34.3 bits (77), Expect = 0.11, Method: Compositional matrix adjust.
Identities = 19/60 (31%), Positives = 30/60 (50%)
Frame = -1
Query: 282 EQLSSGSRDRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWN 341
+ LS+ D ++ DI + + L H V L +S D +LASGG DN + +W+
Sbjct: 735 KYLSTAGADHTVIVWDIASG--TAVAHLTAHTDTVYALCFSRDGTVLASGGMDNSIRLWD 562
Score = 29.6 bits (65), Expect = 3.1, Method: Compositional matrix adjust.
Identities = 16/43 (37%), Positives = 23/43 (53%), Gaps = 2/43 (4%)
Frame = -1
Query: 253 VQIWDAAAGKKLSMLEGHTARVGALAW--NAEQLSSGSRDRMI 293
V +WD A+G ++ L HT V AL + + L+SG D I
Sbjct: 702 VIVWDIASGTAVAHLTAHTDTVYALCFSRDGTVLASGGMDNSI 574
>30295
Length = 593
Score = 40.0 bits (92), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 21/73 (28%), Positives = 38/73 (52%)
Frame = +2
Query: 303 LQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKAIA 362
+++ R L+ H ++ + W+TD + L S D KL+VW+ + + V + V A
Sbjct: 215 MRTRRTLRXHLAKIYAMHWATDSRNLVSASQDGKLIVWDGYTTNKVHAIPLRSSWVMTCA 394
Query: 363 WSPHQHGLLASGG 375
++P G +A GG
Sbjct: 395 YAP-SGGYVACGG 430
>14555
Length = 627
Score = 39.3 bits (90), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 29/86 (33%), Positives = 39/86 (45%), Gaps = 10/86 (11%)
Frame = -3
Query: 417 THGYSQNQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFW------ 470
T+ Y+ N VW + L GH RV L +SPDG ++ TG+ D TLR W
Sbjct: 409 TNDYTVN---VWDALKGMRSTILYGHDNRVSCLRISPDGTSLCTGSWDYTLRIWA*ERER 239
Query: 471 ----NVFSKTRSTKESVSVLNLFTRI 492
N+ T T E L +FT +
Sbjct: 238 GHSSNIIRITL*TWEQCQ*LCVFTWV 161
Score = 28.5 bits (62), Expect = 6.0, Method: Compositional matrix adjust.
Identities = 16/45 (35%), Positives = 24/45 (53%), Gaps = 2/45 (4%)
Frame = -3
Query: 248 THKGFVQIWDAAAGKKLSMLEGHTARVGAL--AWNAEQLSSGSRD 290
T+ V +WDA G + ++L GH RV L + + L +GS D
Sbjct: 409 TNDYTVNVWDALKGMRSTILYGHDNRVSCLRISPDGTSLCTGSWD 275
>18981
Length = 407
Score = 38.1 bits (87), Expect = 0.007, Method: Composition-based stats.
Identities = 28/95 (29%), Positives = 44/95 (46%), Gaps = 1/95 (1%)
Frame = -2
Query: 309 LQGHRQEV-CGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKAIAWSPHQ 367
L+GH +V C + + + SG D L+VW + PV Q H A+ A+ + +
Sbjct: 310 LRGHNDDVECVCIYG---RRVVSGSWDKTLIVWEVDTGRPVHQLHGHTEAITAVQFDEGK 140
Query: 368 HGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQV 402
+ G+AD +R W TGQ L + TG +
Sbjct: 139 -----AVSGSADGDVRTWALDTGQCLLTMTTGQDI 50
Score = 30.4 bits (67), Expect = 1.7, Method: Composition-based stats.
Identities = 18/65 (27%), Positives = 31/65 (47%)
Frame = -2
Query: 241 GNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNAEQLSSGSRDRMILQRDIRT 300
G V G+ + +W+ G+ + L GHT + A+ ++ + SGS D D+RT
Sbjct: 268 GRRVVSGSWDKTLIVWEVDTGRPVHQLHGHTEAITAVQFDEGKAVSGSAD-----GDVRT 104
Query: 301 PPLQS 305
L +
Sbjct: 103 WALDT 89
>10264
Length = 416
Score = 38.1 bits (87), Expect = 0.009, Method: Compositional matrix adjust.
Identities = 25/84 (29%), Positives = 38/84 (45%), Gaps = 1/84 (1%)
Frame = -1
Query: 303 LQSERRLQGHRQEVCGLKWSTDHQL-LASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKAI 361
L S R L GH Q V + WS H L S G D + VW+ + + Q+ H+ +
Sbjct: 275 LTSLRELSGHSQRVTDMSWSPHHDARLVSVGYDAEAFVWDVQKGTALAQFKGHMGRLLTC 96
Query: 362 AWSPHQHGLLASGGGTADRCIRFW 385
+S L+ +GG +D + W
Sbjct: 95 QFSGLDPDLVMTGG--SDASVHVW 30
Score = 28.9 bits (63), Expect = 4.5, Method: Compositional matrix adjust.
Identities = 19/58 (32%), Positives = 29/58 (50%), Gaps = 2/58 (3%)
Frame = -1
Query: 219 VTRLCDLSVEGDSVTSVGWSERGN--LVAVGTHKGFVQIWDAAAGKKLSMLEGHTARV 274
+T L +LS VT + WS + LV+VG + +WD G L+ +GH R+
Sbjct: 275 LTSLRELSGHSQRVTDMSWSPHHDARLVSVG-YDAEAFVWDVQKGTALAQFKGHMGRL 105
>01768
Length = 1424
Score = 37.0 bits (84), Expect = 0.017, Method: Compositional matrix adjust.
Identities = 54/233 (23%), Positives = 94/233 (40%), Gaps = 23/233 (9%)
Frame = +3
Query: 221 RLCDLSVEGDSVTSVGWSERGNLVAVGTHKGFVQIWDAAAGKK--------LSMLEGHTA 272
R+ D++ D + + WS++G++ + DA A K + + HT
Sbjct: 534 RVTDIN---DKIYTGSWSDKGSVYVYDITXQTAIVDDAEAAGKYDSTQKSIVHTVTHHTT 704
Query: 273 RVGALAWNAEQ---LSSGSRDRMILQRDIRTPPLQSERR-LQGHRQEVCGLKWSTDH-QL 327
A+ W+ L +G I + +E+ H V ++WS + +
Sbjct: 705 EGFAIDWSPAAKGWLVTGDCTGAIYISQPSSSGWTTEKSSYAAHTDSVEDVQWSPNEGNV 884
Query: 328 LASGGNDNKLLVWN---HSSLSPVQQYTE-HLAAVKAIAWSPHQHGLLASGGGTADRCIR 383
AS D L +WN S + V E H + I W+P + LLASGG D I+
Sbjct: 885 FASCSVDRTLRIWNTQQKPSKANVLTVPEAHSRDINVINWNPIEKHLLASGGD--DGIIK 1058
Query: 384 FWN--TLTGQPLQC---IDTGSQ-VCNLAWSKHANELVSTHGYSQNQILVWKY 430
W+ +P+ SQ V +L W+ + +++ G +QI +W +
Sbjct: 1059IWDLRMFRNKPVSAQASFKLHSQPVTSLEWNPQDSSVLAASG-EDDQITIWDF 1214
>27475
Length = 369
Score = 37.0 bits (84), Expect = 0.017, Method: Compositional matrix adjust.
Identities = 26/78 (33%), Positives = 40/78 (51%), Gaps = 3/78 (3%)
Frame = +2
Query: 270 HTARVGALAWNAEQ---LSSGSRDRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQ 326
HT V + W+ + SGS D ++ D R+P + + H + + WS +
Sbjct: 65 HTGWVTGVDWSPTREHLFLSGSYDNVLKLWDTRSPK-ATLYDMNWHEDRILAVDWSIP-E 238
Query: 327 LLASGGNDNKLLVWNHSS 344
LL SGG DNKL V+++SS
Sbjct: 239 LLLSGGVDNKLHVFSYSS 292
>31474
Length = 403
Score = 37.0 bits (84), Expect = 0.020, Method: Composition-based stats.
Identities = 27/111 (24%), Positives = 45/111 (40%), Gaps = 5/111 (4%)
Frame = -3
Query: 217 SQVTRLCDLSVEGDSVTSVGWSERGNLVAVGTHKGFVQIWDAAAGK---KLSMLEGHTAR 273
+ + +C LS + V W+ G L+A ++IW K ++ + HT
Sbjct: 341 ATLEEVCCLSAHDEHAWCVAWNPTGTLLASCGSDKIIKIWGKEGDNWVCKSTLTDAHTRT 162
Query: 274 VGALAWN--AEQLSSGSRDRMILQRDIRTPPLQSERRLQGHRQEVCGLKWS 322
V +L W+ LSS S D + + L+GH EV + W+
Sbjct: 161 VRSLGWSPCGNYLSSASFDATTAVWSRKGGEFECIATLEGHENEVKAVAWA 9
Score = 32.3 bits (72), Expect = 0.51, Method: Composition-based stats.
Identities = 27/108 (25%), Positives = 50/108 (46%), Gaps = 7/108 (6%)
Frame = -3
Query: 309 LQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYT---EHLAAVKAIAWSP 365
L H + + W+ LLAS G+D + +W + V + T H V+++ WSP
Sbjct: 317 LSAHDEHAWCVAWNPTGTLLASCGSDKIIKIWGKEGDNWVCKSTLTDAHTRTVRSLGWSP 138
Query: 366 HQHGLLASGGGTADRCIRFWNTLTGQPLQCIDT----GSQVCNLAWSK 409
+ L ++ + D W+ G+ +CI T ++V +AW++
Sbjct: 137 CGNYLSSA---SFDATTAVWSRKGGE-FECIATLEGHENEVKAVAWAR 6
>19863
Length = 502
Score = 37.0 bits (84), Expect = 0.020, Method: Compositional matrix adjust.
Identities = 26/75 (34%), Positives = 34/75 (45%)
Frame = +1
Query: 283 QLSSGSRDRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNH 342
QL SGS D I+ D+ + RLQGH V + +S D L S NDN + +WN
Sbjct: 13 QLVSGSSDMSIVVWDVENGV--QKLRLQGHAGWVNDVHFSQDQCWLLSCSNDNTVRIWNI 186
Query: 343 SSLSPVQQYTEHLAA 357
+ EH A
Sbjct: 187 EESDQIPIVMEHKRA 231
Score = 33.9 bits (76), Expect = 0.17, Method: Compositional matrix adjust.
Identities = 20/60 (33%), Positives = 32/60 (53%)
Frame = +1
Query: 413 ELVSTHGYSQNQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNV 472
+LVS G S I+VW + Q +L GH+ V + S D +++ + D T+R WN+
Sbjct: 13 QLVS--GSSDMSIVVWDVENGVQKLRLQGHAGWVNDVHFSQDQCWLLSCSNDNTVRIWNI 186
>02090
Length = 1841
Score = 36.2 bits (82), Expect = 0.033, Method: Compositional matrix adjust.
Identities = 18/52 (34%), Positives = 27/52 (51%)
Frame = -3
Query: 421 SQNQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNV 472
S I VW + T V + GH+ + +SPDG + TG D T+R W++
Sbjct: 1566 SDGNIAVWDLHNQTLVRQFQGHTDGASCIDISPDGTKLWTGGLDNTVRSWDL 1411
Score = 28.5 bits (62), Expect = 6.4, Method: Compositional matrix adjust.
Identities = 38/167 (22%), Positives = 67/167 (40%)
Frame = -3
Query: 307 RRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKAIAWSPH 366
R+ QGH + S D L +GG DN + W+ +QQ+ + + + ++ + P
Sbjct: 1518 RQFQGHTDGASCIDISPDGTKLWTGGLDNTVRSWDLREGRQLQQH-DFSSQIFSLGYCPT 1342
Query: 367 QHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNLAWSKHANELVSTHGYSQNQIL 426
L G + + Q S V +L ++ VST N +
Sbjct: 1341 GEWLAV---GMESSNVEVLHHSKPDKYQLHLHESCVLSLKFAYCGKWFVSTG--KDNLLN 1177
Query: 427 VWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVF 473
W+ P + + + S VL ++ D + IVTG+GD+ + V
Sbjct: 1176 AWRTPYGASIFQ-SKESSSVLSCDIAADDKYIVTGSGDKKATLYEVI 1039
>13278
Length = 870
Score = 35.8 bits (81), Expect = 0.037, Method: Compositional matrix adjust.
Identities = 26/115 (22%), Positives = 49/115 (42%), Gaps = 9/115 (7%)
Frame = +1
Query: 309 LQGHRQEVCGLKWS---------TDHQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVK 359
LQ +E+ +KWS +LAS D+ + +W + T+H V
Sbjct: 37 LQLTTKEIYTIKWSPTGPGTSNPNTSLILASASFDSTVRLWEVERGLCLHTLTKHQEPVY 216
Query: 360 AIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNLAWSKHANEL 414
++A+SP L + G+ D+C+ WN TG + + + W+ +++
Sbjct: 217 SVAFSPDGKYLAS---GSFDKCVHIWNVQTGSLVHSYKGTGGIFEVCWNHRGDKV 372
Score = 33.5 bits (75), Expect = 0.22, Method: Compositional matrix adjust.
Identities = 14/34 (41%), Positives = 21/34 (61%)
Frame = +1
Query: 439 LTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNV 472
LT H V +A SPDG+ + +G+ D+ + WNV
Sbjct: 190 LTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNV 291
Score = 30.0 bits (66), Expect = 2.1, Method: Compositional matrix adjust.
Identities = 26/94 (27%), Positives = 41/94 (43%), Gaps = 9/94 (9%)
Frame = +1
Query: 309 LQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKAIAWSPH-- 366
L H++ V + +S D + LASG D + +WN + S V Y + + + W+
Sbjct: 190 LTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNVQTGSLVHSY-KGTGGIFEVCWNHRGD 366
Query: 367 QHGLLASGGGTA-------DRCIRFWNTLTGQPL 393
+ G AS G D+C W+ L PL
Sbjct: 367 KVGASASDGSVFVLDLRK*DKCSNSWHMLLLPPL 468
>01462
Length = 995
Score = 35.8 bits (81), Expect = 0.043, Method: Compositional matrix adjust.
Identities = 27/111 (24%), Positives = 49/111 (44%), Gaps = 12/111 (10%)
Frame = +2
Query: 253 VQIWDAAAGKKLSMLEGHTARVGALAW--NAEQLSSGSRDRMILQRDIRTPPLQSERRLQ 310
+ +WD AG+ L+ +EGH + + +A++ S S D + DIR+ ++ L+
Sbjct: 269 IHVWDIEAGQYLNAMEGHKDYIHKVVMKNDAQECVSASEDGTVRMWDIRS-STETVHCLE 445
Query: 311 GHRQEVCG----------LKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQY 351
+ E+C L + L GG KL W+ +L+P +
Sbjct: 446 PSKNELCSRPLLGKWLRCLALDPEEGWLVCGGGP-KLSAWHLRTLAPTTIF 595
Score = 33.1 bits (74), Expect = 0.27, Method: Compositional matrix adjust.
Identities = 18/68 (26%), Positives = 32/68 (47%)
Frame = +2
Query: 419 GYSQNQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKTRS 478
G +I VW + + + GH + + M D + V+ + D T+R W++ RS
Sbjct: 251 GAGDRKIHVWDIEAGQYLNAMEGHKDYIHKVVMKNDAQECVSASEDGTVRMWDI----RS 418
Query: 479 TKESVSVL 486
+ E+V L
Sbjct: 419 STETVHCL 442
>26107
Length = 1338
Score = 35.8 bits (81), Expect = 0.044, Method: Compositional matrix adjust.
Identities = 59/256 (23%), Positives = 96/256 (37%), Gaps = 36/256 (14%)
Frame = -3
Query: 253 VQIWDAAAGKKLSMLEGHTARVGALAW---NAEQLSSGSRDRMILQRDIRTPPLQSERRL 309
V +WD K++ GH V ++A + Q +SG+RD I+ D R + +R
Sbjct: 1015 VALWDVETTTKVTTFIGHKCSVRSVASCPSSPAQCASGARDGHIMLWDSR---VNKKREH 845
Query: 310 QGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAA--------VKAI 361
Q Q HQ+ G+ +K P + H AA +++
Sbjct: 844 QPCSQV---------HQVCPQSGHQSK----------PAKHRRIHRAAGPKGVMDTQQSV 722
Query: 362 AWSPHQHGLLASGGGTADRCIRFW-------NTLTG--QPLQCIDTGSQV---------C 403
+Q L G D C++ W NT T P+ D + C
Sbjct: 721 TCVLYQTDNLIISSGANDGCVKMWDTRKWYTNTTTSLPVPVHTFDYPGHMRRLKGIVTMC 542
Query: 404 NLAWSKHANELVSTHGYSQNQILVWKYPSLTQVAK-----LTGHSYRVLYL--AMSPDGE 456
W + VS Y+ N+ V++Y Q + GH ++ A+SPDG+
Sbjct: 541 MDPWK--SQLFVS---YTDNK--VYRYQLAGQYREPQEYVYAGHRNDTFFVRCAISPDGK 383
Query: 457 AIVTGAGDETLRFWNV 472
+++G+G T W V
Sbjct: 382 YLLSGSGRNTGVIWEV 335
Score = 30.8 bits (68), Expect = 1.3, Method: Compositional matrix adjust.
Identities = 22/81 (27%), Positives = 35/81 (43%), Gaps = 1/81 (1%)
Frame = -3
Query: 308 RLQGHRQEVCGLKW-STDHQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKAIAWSPH 366
R H V W S D Q L + G D + +W+ + + V + H +V+++A P
Sbjct: 1102 RWXAHNNAVFDYSWISNDSQCLTASG-DQTVALWDVETTTKVTTFIGHKCSVRSVASCPS 926
Query: 367 QHGLLASGGGTADRCIRFWNT 387
ASG D I W++
Sbjct: 925 SPAQCASGA--RDGHIMLWDS 869
>37142
Length = 327
Score = 35.0 bits (79), Expect = 0.075, Method: Compositional matrix adjust.
Identities = 27/104 (25%), Positives = 51/104 (49%), Gaps = 12/104 (11%)
Frame = +2
Query: 327 LLASGGNDNKLLVWNHSSL------SPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTADR 380
++ G ++ +LV++ + V Q T+H AVKA+ ++P Q LLASG ++
Sbjct: 2 VIVGGADNGSVLVYSAQKMIDGDADCSVLQLTKHTGAVKALDFNPFQTNLLASGASESE- 178
Query: 381 CIRFW------NTLTGQPLQCIDTGSQVCNLAWSKHANELVSTH 418
I W N +T P Q +V +AW++ +++++
Sbjct: 179 -IYIWDLNKPDNPMT--PGQKSQPPEEVSCVAWNRQVQHILASN 301
>31054
Length = 392
Score = 34.7 bits (78), Expect = 0.085, Method: Compositional matrix adjust.
Identities = 16/51 (31%), Positives = 30/51 (58%)
Frame = -2
Query: 421 SQNQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWN 471
S + + WK+P + L+GH+ + LA++ DG +V+GA + T+ W+
Sbjct: 355 SPDXVKQWKFPDGNFIQNLSGHNAIINTLAVNSDG-VLVSGADNGTMHLWD 206
>12140
Length = 727
Score = 34.3 bits (77), Expect = 0.12, Method: Compositional matrix adjust.
Identities = 30/106 (28%), Positives = 46/106 (43%), Gaps = 9/106 (8%)
Frame = +2
Query: 247 GTHKGFVQIW--DAAAGKKLSMLEGHTARVGALAWNA------EQLSSGSRD-RMILQRD 297
G V+IW D + LEGH+ V +AW ++S S+D R+I+ +
Sbjct: 278 GGCDNLVKIWREDETGWVEDQKLEGHSDWVRDVAWAPSIGLPRNVIASCSQDCRVIIWTN 457
Query: 298 IRTPPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHS 343
+ + R L V + WS +LA G DNK+ +W S
Sbjct: 458 DGSSNQWTSRILNKFSDVVWHVSWSVTGNILAVSGGDNKVTLWKES 595
>21921
Length = 1341
Score = 34.3 bits (77), Expect = 0.13, Method: Compositional matrix adjust.
Identities = 19/77 (24%), Positives = 37/77 (48%)
Frame = -1
Query: 351 YTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNLAWSKH 410
Y H V++I P L++ G+ D IRFW +G+ ++ + G V ++AW+ +
Sbjct: 495 YKGHTGIVRSICPDPTGQWLVS---GSDDGTIRFWEVSSGRCMKTLQVGGCVTSVAWNPN 325
Query: 411 ANELVSTHGYSQNQILV 427
+ V + +L+
Sbjct: 324 PSLCVVAATLNTTVLLI 274
Score = 33.5 bits (75), Expect = 0.18, Method: Compositional matrix adjust.
Identities = 16/41 (39%), Positives = 23/41 (56%)
Frame = -1
Query: 434 TQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFS 474
TQ GH+ V + P G+ +V+G+ D T+RFW V S
Sbjct: 510 TQALVYKGHTGIVRSICPDPTGQWLVSGSDDGTIRFWEVSS 388
>34511
Length = 1037
Score = 33.5 bits (75), Expect = 0.22, Method: Compositional matrix adjust.
Identities = 16/38 (42%), Positives = 22/38 (57%)
Frame = +3
Query: 439 LTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKT 476
L GH RV L ++ +G ++ TG+ D LR WN S T
Sbjct: 60 LAGHDNRVSCLGVTENGMSVATGSWDSFLRVWN*VSCT 173
>19140
Length = 573
Score = 33.1 bits (74), Expect = 0.29, Method: Compositional matrix adjust.
Identities = 13/38 (34%), Positives = 24/38 (63%)
Frame = -3
Query: 435 QVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNV 472
++ KL GH+ V L ++ DG ++G+ D T+R W++
Sbjct: 511 KLMKLKGHTDNVKALVLNRDGTQCLSGSSDGTIRLWSL 398
>15337
Length = 860
Score = 32.7 bits (73), Expect = 0.30, Method: Compositional matrix adjust.
Identities = 15/49 (30%), Positives = 26/49 (53%)
Frame = -1
Query: 427 VWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSK 475
V+ Y S+ + + + +L + SPDG+ IVTG D+ + W+ K
Sbjct: 251 VFNYNSMELIGTMKSYFGGLLCVCWSPDGKYIVTGGEDDLVTVWSFHEK 105
Score = 28.5 bits (62), Expect = 6.7, Method: Compositional matrix adjust.
Identities = 13/46 (28%), Positives = 23/46 (50%)
Frame = -1
Query: 321 WSTDHQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKAIAWSPH 366
WS D + + +GG D+ + VW+ V + H + V +A+ H
Sbjct: 179 WSPDGKYIVTGGEDDLVTVWSFHEKRVVCRGHGHKSWVNVVAFDIH 42
>21105
Length = 650
Score = 32.7 bits (73), Expect = 0.34, Method: Compositional matrix adjust.
Identities = 14/41 (34%), Positives = 25/41 (60%)
Frame = +1
Query: 436 VAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKT 476
+ + H V LA+ P+G +++G+ D ++R WN+ SKT
Sbjct: 169 IHAMVAHLDSVTSLAVDPNGLYLLSGSHDCSIRLWNLDSKT 291
Score = 28.5 bits (62), Expect = 7.1, Method: Compositional matrix adjust.
Identities = 27/97 (27%), Positives = 40/97 (41%), Gaps = 4/97 (4%)
Frame = +1
Query: 286 SGSRDRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSL 345
+ DR I D T L + H V L + L SG +D + +WN S
Sbjct: 115 TAHEDRHIRFFDNNTGKLI--HAMVAHLDSVTSLAVDPNGLYLLSGSHDCSIRLWNLDSK 288
Query: 346 SPVQQYTEHL----AAVKAIAWSPHQHGLLASGGGTA 378
+ VQ+ T H ++ +A+ P Q +AS G A
Sbjct: 289 TCVQEITSHRKKFDESIHDVAFHP-QKPYIASAGADA 396
>01584
Length = 1540
Score = 32.7 bits (73), Expect = 0.36, Method: Compositional matrix adjust.
Identities = 17/51 (33%), Positives = 27/51 (52%), Gaps = 1/51 (1%)
Frame = -2
Query: 384 FWNTLTGQPLQCIDTGSQVCNLAW-SKHANELVSTHGYSQNQILVWKYPSL 433
FW +TG+ L C VC W +HA ++S H S+ ++ ++PSL
Sbjct: 678 FWLIITGKHLACTRGNHGVCLAPW*REHAVAVLSHHARSKVRVTSCQHPSL 526
>15972
Length = 1069
Score = 32.7 bits (73), Expect = 0.37, Method: Compositional matrix adjust.
Identities = 14/33 (42%), Positives = 20/33 (60%)
Frame = +3
Query: 439 LTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWN 471
+GH V +LA+ P G+ +T + D TLR WN
Sbjct: 225 FSGHKGPVRHLAVHPSGKLTLTVSQDRTLRLWN 323
>15118
Length = 1074
Score = 32.3 bits (72), Expect = 0.46, Method: Compositional matrix adjust.
Identities = 29/123 (23%), Positives = 54/123 (43%), Gaps = 4/123 (3%)
Frame = +3
Query: 354 HLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQP----LQCIDTGSQVCNLAWSK 409
H++ V+ +A+ LL + GG D I+FW + L+ + + + +
Sbjct: 189 HVSGVRGVAFDAFN-CLLITAGGDCD--IKFWRFGSRDRARVLLKELKMSEGISRILLHR 359
Query: 410 HANELVSTHGYSQNQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRF 469
+N L + V +L V +GHS + L+ S DG ++T + D T+R
Sbjct: 360 DSNMLAVV--LEDFTVSVIDVDTLRVVRVFSGHSNSITDLSFSGDGRWLITASMDCTVRT 533
Query: 470 WNV 472
W++
Sbjct: 534 WSL 542
>36111
Length = 687
Score = 31.6 bits (70), Expect = 0.80, Method: Compositional matrix adjust.
Identities = 14/48 (29%), Positives = 22/48 (45%)
Frame = +2
Query: 232 VTSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAW 279
V +V + N A G G+V IWD K+L + + +LA+
Sbjct: 239 VNAVAFHNVYNTFATGGSDGYVNIWDGFHKKRLCXFHRYPTSIASLAF 382
>27270
Length = 1078
Score = 31.6 bits (70), Expect = 0.85, Method: Compositional matrix adjust.
Identities = 25/91 (27%), Positives = 40/91 (43%), Gaps = 6/91 (6%)
Frame = +2
Query: 310 QGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKAIAWSPHQHG 369
+GH + V + W D + L S D ++ WN ++L ++++ A S HG
Sbjct: 263 KGHSKAVTDMCWRADGRTLYSSSLDGHVIGWNVNTLHMIEKWK---------ATSGRHHG 415
Query: 370 L----LASGGG--TADRCIRFWNTLTGQPLQ 394
+ L S TAD I+ W+ T LQ
Sbjct: 416 VHCVCLCSSSRLLTADHTIKMWDLTTKNVLQ 508
>10162
Length = 1629
Score = 31.2 bits (69), Expect = 0.94, Method: Compositional matrix adjust.
Identities = 20/88 (22%), Positives = 42/88 (47%), Gaps = 2/88 (2%)
Frame = +3
Query: 391 QPLQCIDTGSQVCNLAWSKHANELVSTHGYSQNQILVWKYPS--LTQVAKLTGHSYRVLY 448
Q + + GS + L W A+ L++ G ++ +W+ PS +++ L H L
Sbjct: 3 QQIWSYECGSDITWLQWHGGAHVLLA--GTQGGEVWLWQVPSQDYSKMKMLQSHGQPSLC 176
Query: 449 LAMSPDGEAIVTGAGDETLRFWNVFSKT 476
+ P+G+ + G D ++ W++ + T
Sbjct: 177 GKILPNGKYVCVGYSDGVVKLWDLKTGT 260
Score = 28.9 bits (63), Expect = 4.7, Method: Compositional matrix adjust.
Identities = 18/65 (27%), Positives = 30/65 (46%), Gaps = 4/65 (6%)
Frame = +3
Query: 230 DSVTSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNAEQ----LS 285
+ V + WS L+ G +++WDA +G ++L GH L ++ + L
Sbjct: 645 EGVCKLQWSSSTALLYTACLDGVMRVWDARSGASKAVLTGHARNSCILDFDVTRDGTCLV 824
Query: 286 SGSRD 290
SGS D
Sbjct: 825 SGSED 839
>11493
Length = 535
Score = 30.8 bits (68), Expect = 1.2, Method: Compositional matrix adjust.
Identities = 38/163 (23%), Positives = 68/163 (41%), Gaps = 6/163 (3%)
Frame = -2
Query: 312 HRQEVCGLKWSTDHQLLASGGNDNKLLVWNHS---SLSPVQQY--TEHLAAVKAIAWSPH 366
H + VC + S + + +GG + VW+ S + +PV Q + ++++ P
Sbjct: 480 HGEVVCAVTISNPTKYVYTGGK-GCVKVWDISQPGNKNPVSQLDCLQRDNYIRSVKLLPD 304
Query: 367 QHGLLASGGGTADRCIRFWNTLTGQP-LQCIDTGSQVCNLAWSKHANELVSTHGYSQNQI 425
L+ GG A + W+ + P ++ T + A + + V S I
Sbjct: 303 GRTLIV--GGEASN-LSIWDLASPTPRIKAELTSAAPACYALAISPDSKVCFSCCSDGNI 133
Query: 426 LVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLR 468
VW + V + GH+ + +SPDG + TG D T+R
Sbjct: 132 AVWDLHNEILVRQFQGHTDGASCIDISPDGSRLWTGGLDNTVR 4
>27681
Length = 465
Score = 30.8 bits (68), Expect = 1.3, Method: Compositional matrix adjust.
Identities = 12/31 (38%), Positives = 19/31 (61%)
Frame = +2
Query: 446 VLYLAMSPDGEAIVTGAGDETLRFWNVFSKT 476
V A +P + + +G+GD T R WN+ S+T
Sbjct: 2 VFICAWNPTNDLLASGSGDSTARIWNMTSET 94
Score = 30.4 bits (67), Expect = 1.5, Method: Compositional matrix adjust.
Identities = 10/25 (40%), Positives = 18/25 (72%)
Frame = +2
Query: 232 VTSVGWSERGNLVAVGTHKGFVQIW 256
VTS+ W+ G L+A G++ G+ ++W
Sbjct: 170 VTSLDWNSEGTLLATGSYDGYARLW 244
Score = 28.5 bits (62), Expect = 6.3, Method: Composition-based stats.
Identities = 13/39 (33%), Positives = 20/39 (51%)
Frame = +3
Query: 313 RQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQY 351
R + LKW+ + S G D ++W+ SS S QQ+
Sbjct: 285 RAPIFALKWNKRGNYILSAGVDKTTIIWDASSGSCTQQF 401
>07665
Length = 435
Score = 30.4 bits (67), Expect = 1.6, Method: Compositional matrix adjust.
Identities = 30/102 (29%), Positives = 43/102 (42%), Gaps = 14/102 (13%)
Frame = -2
Query: 256 WDAAAGKKLSMLEGHTARVGALAWNAEQLSSGSRDRMILQR--DIRTPPLQSERRLQGHR 313
WD GK L LE H + AL + S +R + + I+ L ++ ++ R
Sbjct: 392 WDLNDGKNLYTLE-HNDIINALCF------SPNRYWLCVAYGPSIKIWDLACKKTVEELR 234
Query: 314 QEVCG------------LKWSTDHQLLASGGNDNKLLVWNHS 343
EV L WSTD Q L +G +DN + VW S
Sbjct: 233 PEVVSPTSKAEQPQCLSLAWSTDGQTLFAGYSDNTIRVWQVS 108
Score = 29.3 bits (64), Expect = 4.2, Method: Compositional matrix adjust.
Identities = 12/28 (42%), Positives = 16/28 (57%)
Frame = -2
Query: 445 RVLYLAMSPDGEAIVTGAGDETLRFWNV 472
+ L LA S DG+ + G D T+R W V
Sbjct: 194 QCLSLAWSTDGQTLFAGYSDNTIRVWQV 111
>28289
Length = 349
Score = 30.0 bits (66), Expect = 2.5, Method: Composition-based stats.
Identities = 24/86 (27%), Positives = 41/86 (47%), Gaps = 5/86 (5%)
Frame = -1
Query: 259 AAGKKLSM---LEGHTARVGALAWNA--EQLSSGSRDRMILQRDIRTPPLQSERRLQGHR 313
AA LSM LEGH+ V +AWN ++L++ + +I+ + E ++
Sbjct: 277 AAPSNLSMNQSLEGHSGAVQVVAWNEHHQKLTTSDQYGLIIVWMLYKGSWYEEMINNRNK 98
Query: 314 QEVCGLKWSTDHQLLASGGNDNKLLV 339
V G+KW+ D Q + D ++V
Sbjct: 97 SVVRGMKWTADGQKICIVYEDGAVIV 20
>17807
Length = 484
Score = 29.6 bits (65), Expect = 2.6, Method: Compositional matrix adjust.
Identities = 20/74 (27%), Positives = 32/74 (43%)
Frame = -2
Query: 200 VLSVGLGTCVYLWSACTSQVTRLCDLSVEGDSVTSVGWSERGNLVAVGTHKGFVQIWDAA 259
LS L + LW+ +VT +LS + +T+ + G L VGT+ G +
Sbjct: 414 FLSGSLDGKIRLWNIPDKKVTMWNELSGSSNLITTASFCHNGRLAVVGTYDGRCIFYTTD 235
Query: 260 AGKKLSMLEGHTAR 273
K +ML + R
Sbjct: 234 QLKYYTMLNVRSTR 193
>21025
Length = 444
Score = 28.9 bits (63), Expect = 4.6, Method: Composition-based stats.
Identities = 13/41 (31%), Positives = 24/41 (58%)
Frame = +1
Query: 14 VIQNENTMPRVTEMRRTLTPASSPVSSPSKHGDRFIPSRAG 54
V++ ++T+ ++ + L P+ SPV +KHG +I S A
Sbjct: 127 VLRQQHTVDTISRLMLVL*PSYSPVCQHAKHGKLYIISMAA 249
>30679
Length = 1025
Score = 28.9 bits (63), Expect = 5.4, Method: Compositional matrix adjust.
Identities = 13/61 (21%), Positives = 33/61 (54%), Gaps = 2/61 (3%)
Frame = +1
Query: 255 IWDAAAGKKLSMLEGHTARVGALAWN--AEQLSSGSRDRMILQRDIRTPPLQSERRLQGH 312
+W+ + +++++ HT + +++WN ++ S+D+ + D RT + +E Q H
Sbjct: 40 VWNVEQAEPVNIVDCHTDTIFSMSWNRXGSMFATTSKDKKLRTIDPRTTTVAAES--QCH 213
Query: 313 R 313
+
Sbjct: 214 K 216
>12841
Length = 1364
Score = 28.9 bits (63), Expect = 5.4, Method: Compositional matrix adjust.
Identities = 21/79 (26%), Positives = 31/79 (39%)
Frame = +1
Query: 181 APELQDDFYLNLVDWSSLNVLSVGLGTCVYLWSACTSQVTRLCDLSVEGDSVTSVGWSER 240
+P + D F DWS + LW + T + +V V WS R
Sbjct: 1075 SPFVSDIFLSCSADWS------------IRLWHQ--DRTTPILTFHSSTKTVHDVCWSPR 1212
Query: 241 GNLVAVGTHKGFVQIWDAA 259
+ V H+G V++WD A
Sbjct: 1213 SSTVFACVHEGAVEVWDLA 1269
>16199
Length = 694
Score = 28.9 bits (63), Expect = 5.5, Method: Compositional matrix adjust.
Identities = 17/63 (26%), Positives = 31/63 (49%), Gaps = 3/63 (4%)
Frame = +2
Query: 221 RLCDLSVEGDSV---TSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGAL 277
++CD S G SV T + G + A GT ++IWD ++ +GH V ++
Sbjct: 44 KVCDKS--GPSVPALTCAQFHPDGLIFATGTEDSVIKIWDLKERANVANFQGHQGPVTSI 217
Query: 278 AWN 280
+++
Sbjct: 218 SFS 226
>00105
Length = 1426
Score = 28.5 bits (62), Expect = 6.4, Method: Compositional matrix adjust.
Identities = 10/28 (35%), Positives = 16/28 (57%)
Frame = +3
Query: 366 HQHGLLASGGGTADRCIRFWNTLTGQPL 393
H HG+ G + +RC+ L+GQP+
Sbjct: 1131 HNHGVFVGRGYSLERCMVLCGVLSGQPM 1214
>38177
Length = 430
Score = 28.5 bits (62), Expect = 6.8, Method: Compositional matrix adjust.
Identities = 17/71 (23%), Positives = 34/71 (47%), Gaps = 2/71 (2%)
Frame = +3
Query: 319 LKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTA 378
L W+ + + L +G + + +WN + + H +V+A+ WS H ++ TA
Sbjct: 6 LAWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDVSVRAMRWSNHDQWMV-----TA 170
Query: 379 DRC--IRFWNT 387
D I++W +
Sbjct: 171 DHSGYIKYWQS 203
>17602
Length = 481
Score = 28.5 bits (62), Expect = 7.1, Method: Compositional matrix adjust.
Identities = 18/67 (26%), Positives = 29/67 (43%), Gaps = 5/67 (7%)
Frame = +3
Query: 232 VTSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWN-----AEQLSS 286
V+ V +S G + T +++WD + GK L GH + N + + S
Sbjct: 192 VSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYVGHRNEKYCIFANFSVTGGKWIVS 371
Query: 287 GSRDRMI 293
GS D M+
Sbjct: 372 GSEDNMV 392
Score = 27.7 bits (60), Expect = 9.6, Method: Compositional matrix adjust.
Identities = 13/38 (34%), Positives = 22/38 (57%)
Frame = +3
Query: 446 VLYLAMSPDGEAIVTGAGDETLRFWNVFSKTRSTKESV 483
V ++ SP+G+ I+ D TL+ W+ +SK + K V
Sbjct: 192 VSFVKFSPNGKYILAATLDNTLKLWD-YSKGKCLKTYV 302
>30297
Length = 822
Score = 28.1 bits (61), Expect = 7.7, Method: Compositional matrix adjust.
Identities = 30/119 (25%), Positives = 44/119 (36%), Gaps = 18/119 (15%)
Frame = -3
Query: 302 PLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWN--------HSSLSPVQQYTE 353
P ++ GH+++V + LLA+ D +++VWN H P YT+
Sbjct: 733 PYWADDERDGHKEDVLAVAHCLP-NLLATASYDGEVIVWNMVSGHIFCHLRPPPPADYTD 557
Query: 354 H----------LAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQV 402
L +K A+ L+ASG I WN G L G QV
Sbjct: 556 QSLDGDLGISKLLFLKTRAYKKDAGSLVASGPRAH---IHIWNVFQGGRLMAQFPGVQV 389
>30108
Length = 1032
Score = 27.7 bits (60), Expect = 9.8, Method: Compositional matrix adjust.
Identities = 43/176 (24%), Positives = 69/176 (39%), Gaps = 13/176 (7%)
Frame = +1
Query: 312 HRQEVCGLKWSTDHQLLASGGNDNKLLV-WNHSSLSPVQQYTEHLAAVKAIAWSPHQHGL 370
H V W A DN + V ++ S+L PV ++ +V +AW P +
Sbjct: 97 HESPVRAFAWHPHTTKFALALQDNSVHVHYSASTLVPVLKHKLQ-KSVAHLAWQPLSASV 273
Query: 371 LASGGGTADRCIRFWN----TLTGQP----LQCIDTGSQ--VCNLAWSKHANELVSTHGY 420
LA +A + W+ +L +P +Q + + +LAW AN L+S
Sbjct: 274 LAVACQSA---VLIWHIEPTSLAARPSSSSVQVLQHSGHCPITHLAWLPSANILLSASPV 444
Query: 421 SQNQILVWKY--PSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFS 474
++ W + T + L G V LA SPDG ++ R W+ S
Sbjct: 445 -DTAVMAWSVGGEACTALRYLGGGG--VSLLACSPDGSKVMAATPATLFRVWDTTS 603
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000354619 | hsapiens_gene_ensembl | Casein kinase
II subunit alpha (EC 2.7.11.1) (CK II).
[Source:Uniprot/SWISSPROT;Acc:P68400]
(255 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
03508 194 4e-50
01060 102 2e-22
14126 99 2e-21
04591 89 2e-18
01707 87 5e-18
04138 87 8e-18
32000 85 3e-17
29581 80 1e-15
01756 71 3e-13
15910 69 2e-12
23319 69 3e-12
21079 67 7e-12
12721 62 3e-10
28638 60 9e-10
01392 59 2e-09
26560 59 2e-09
14420 58 5e-09
01966 57 7e-09
03294 55 2e-08
26711 55 3e-08
12786 55 3e-08
13212 55 3e-08
30755 54 4e-08
18287 54 5e-08
19761 54 6e-08
00300 52 2e-07
18921 52 3e-07
18484 51 4e-07
09606 50 7e-07
13592 50 7e-07
18401 50 8e-07
00638 50 1e-06
19094 49 1e-06
31885 49 2e-06
13078 48 3e-06
21433 47 8e-06
13066 45 3e-05
27405 45 4e-05
04852 44 4e-05
03240 43 1e-04
11185 42 2e-04
00715 42 3e-04
17975 41 6e-04
05084 39 0.003
14116 38 0.003
01718 38 0.003
26009 38 0.004
00392 38 0.004
31489 36 0.014
37602 35 0.031
02638 35 0.033
18481 35 0.036
27546 34 0.046
06358 34 0.068
29590 33 0.088
15931 33 0.10
11801 33 0.13
26909 33 0.14
14104 32 0.29
28157 32 0.31
12672 31 0.43
21800 31 0.60
27274 30 0.65
35032 30 0.92
37063 30 1.0
17932 30 1.0
16350 29 1.4
19301 29 1.6
29360 29 1.9
20513 28 2.4
18663 28 2.5
28419 28 2.8
20773 28 3.2
32359 28 3.2
20152 28 4.0
01106 28 4.3
21210 28 4.4
37603 27 6.7
>03508
Length = 1463
Score = 194 bits (492), Expect = 4e-50, Method: Compositional matrix adjust.
Identities = 86/97 (88%), Positives = 93/97 (95%)
Frame = +1
Query: 1 MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRY 60
+YE++KALD+CHSMGIMHRDVKPHNVMIDHE++KLRLIDWGLAEFYHPG EYNVRVASRY
Sbjct: 889 LYELMKALDFCHSMGIMHRDVKPHNVMIDHENKKLRLIDWGLAEFYHPGMEYNVRVASRY 1068
Query: 61 FKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFF 97
FKGPELL+DYQMYDYSLDMWSLGCM ASMIFRKEP
Sbjct: 1069FKGPELLLDYQMYDYSLDMWSLGCMFASMIFRKEPLL 1179
Score = 185 bits (470), Expect = 1e-47, Method: Compositional matrix adjust.
Identities = 89/115 (77%), Positives = 97/115 (84%), Gaps = 3/115 (2%)
Frame = +2
Query: 80 WSLGCMLASM---IFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDI 136
W+ G A + K PFFHGHDNYDQLVRIAKVLGT+DLY YI+KY I+LDPRFNDI
Sbjct: 1118 WTCGVWAACLPA*SSGKSPFFHGHDNYDQLVRIAKVLGTDDLYGYIEKYQIDLDPRFNDI 1297
Query: 137 LGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTV 191
LGRHSRKRWERFVHSENQHL+SPEALDFLDKLLRYDH RLTAREAM+HPYF +
Sbjct: 1298 LGRHSRKRWERFVHSENQHLISPEALDFLDKLLRYDHNERLTAREAMDHPYFXPI 1462
>01060
Length = 1800
Score = 102 bits (253), Expect = 2e-22, Method: Compositional matrix adjust.
Identities = 54/192 (28%), Positives = 103/192 (53%), Gaps = 1/192 (0%)
Frame = +1
Query: 1 MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAE-FYHPGQEYNVRVASR 59
+++I+ + +CH I+HRD+KP N++I+H +++ D+G+A F P + Y V +
Sbjct: 394 VFQIVTGIXFCHQRRIVHRDLKPQNLLINHTG-AIKIADFGMARTFALPVRAYTHEVVTL 570
Query: 60 YFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLY 119
+++ PE+L+ Y +D+WS+G + A M+ R P F G DQL +I +++GT
Sbjct: 571 WYRAPEILMGASKYSTPVDVWSIGTIFADMLIRT-PIFKGDSEIDQLFKIFRIIGTPTEQ 747
Query: 120 DYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTA 179
+ + + + P FN + W+ SE + LD +++ L+ D R++
Sbjct: 748 TWPEFHKL---PAFNGMF-----PLWKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISC 903
Query: 180 REAMEHPYFYTV 191
++ ++H YF V
Sbjct: 904 KKMLQHAYFLNV 939
>14126
Length = 1265
Score = 98.6 bits (244), Expect = 2e-21, Method: Compositional matrix adjust.
Identities = 58/191 (30%), Positives = 100/191 (52%), Gaps = 3/191 (1%)
Frame = +3
Query: 1 MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRY 60
M ++L +D+ HS I+HRD+KP N++I + R L+L D+GLA Y V + +
Sbjct: 534 MLQLLNGVDFLHSNRIVHRDLKPQNLLISKDGR-LKLADFGLARIYSFHMALTTVVVTLW 710
Query: 61 FKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYD 120
++ PE+L+ + Y S+D+WS GC+ A + F + F G +DQL +I +V+G D
Sbjct: 711 YRSPEVLMQAE-YGTSVDIWSCGCIFAEL-FTRRALFKGSSEFDQLKKIFEVIGLPPAGD 884
Query: 121 YIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLV---SPEALDFLDKLLRYDHQSRL 177
+ + ++ R + Q LV P+A D ++K+L + R+
Sbjct: 885 WPEGVSVH-------------RNSFRPTPPVPLQTLVPEMDPQAKDLMEKMLVFKSGRRI 1025
Query: 178 TAREAMEHPYF 188
++RE++ HPY
Sbjct: 1026SSRESLLHPYL 1058
>04591
Length = 1117
Score = 88.6 bits (218), Expect = 2e-18, Method: Compositional matrix adjust.
Identities = 55/190 (28%), Positives = 95/190 (50%)
Frame = -2
Query: 1 MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRY 60
M ++L L Y H+ I+HRD+K N+++ + L+L D+GL+ + + RV + +
Sbjct: 879 MSQLLNGLFYIHTKQILHRDIKAANILLTRDG-VLKLADFGLSRPWVKSKRLTNRVVTLW 703
Query: 61 FKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYD 120
++ PELL+ + Y +DMW +GC++A M RK P G QL I + G+ +
Sbjct: 702 YRPPELLLGEREYGPEIDMWGVGCIMAEMWSRK-PLMQGRSEQHQLSLITDLCGSLNAEV 526
Query: 121 YIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAR 180
+ +EL + + G+ RK ER + L + E + +D LR D R+
Sbjct: 525 WPGVTKLELYGKLDLPQGK-PRKVKERML----DLLKNKEGAELIDIFLRLDPGQRMNCD 361
Query: 181 EAMEHPYFYT 190
A+ H +F+
Sbjct: 360 NALSHDFFWV 331
>01707
Length = 757
Score = 87.4 bits (215), Expect = 5e-18, Method: Compositional matrix adjust.
Identities = 43/115 (37%), Positives = 70/115 (60%), Gaps = 1/115 (0%)
Frame = +1
Query: 1 MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYH-PGQEYNVRVASR 59
+Y+ L A+++CH +HRDVKP N++I + +++L D+G A PG EY VA+R
Sbjct: 379 IYQTLLAVNFCHQYNTIHRDVKPENILITRQG-QVKLCDFGFARILTGPGDEYTDYVATR 555
Query: 60 YFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLG 114
+++ PELLV Y +D+W++GC+ A ++ + + G + DQL I K LG
Sbjct: 556 WYRAPELLVGDTQYGPPVDVWAIGCVFAELL-TGQALWPGRSDVDQLHLIRKTLG 717
>04138
Length = 800
Score = 86.7 bits (213), Expect = 8e-18, Method: Compositional matrix adjust.
Identities = 56/195 (28%), Positives = 101/195 (51%), Gaps = 6/195 (3%)
Frame = +1
Query: 8 LDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPG----QEYNVRVASRYFKG 63
L Y H I+HRD+K N++I + L+L D+GLA + Y RV + +++
Sbjct: 52 LYYIHRNKILHRDMKAANILITKQG-VLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRP 228
Query: 64 PELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLG--TEDLYDY 121
PELL+ + Y ++D W GC++A M + + P G +QL I ++ G T +++
Sbjct: 229 PELLLGDRNYSTAIDQWGAGCIMAEM-WTRNPIMQGTTEQNQLTLITQLCGSITPEVWPG 405
Query: 122 IDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTARE 181
+ + ++ + GR + R +RF + L P LD ++LL+ D R++A E
Sbjct: 406 VTQLSMYHQIKGALAAGRKNIIR-DRFA----RILKDPYGLDLFERLLKMDPSQRISADE 570
Query: 182 AMEHPYFYTVVKDQA 196
A+ H +F+ V+ ++
Sbjct: 571 ALNHDFFWVGVEPKS 615
>32000
Length = 644
Score = 85.1 bits (209), Expect = 3e-17, Method: Compositional matrix adjust.
Identities = 52/158 (32%), Positives = 81/158 (51%), Gaps = 3/158 (1%)
Frame = -1
Query: 34 KLRLIDWGLAE-FYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFR 92
K+++ D+GLA F P + Y V + +++ PE+L+ + Y +D+WSLGC+ M+ R
Sbjct: 575 KMKIADFGLARVFGLPVRTYTHEVITLWYRAPEILLGCRFYSVPVDIWSLGCIFVEMMTR 396
Query: 93 KEPFFHGHDNYDQLVRIAKVLGT--EDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVH 150
+ F G DQL RI + LGT E ++ + K P + + K E V
Sbjct: 395 RA-LFPGDSEIDQLYRIFRTLGTPDEKVWPGVSKL-----PDYKPTFPKWPLKNLETVVS 234
Query: 151 SENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYF 188
+S LD L ++L Y+ R++AR AM HPYF
Sbjct: 233 ------LSKVGLDLLKRMLTYNPNRRISARSAMRHPYF 138
>29581
Length = 1278
Score = 79.7 bits (195), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 54/197 (27%), Positives = 100/197 (50%), Gaps = 9/197 (4%)
Frame = -2
Query: 1 MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFY-HPGQEYNVRVASR 59
+ ++LK L Y H I+HRD+K N+++ + +++ D+GLA Y P + +V +
Sbjct: 1031 VLQLLKGLRYLHEAFIIHRDLKVSNLLMT-DKGCVKIADFGLARNYGKPQKPMTPKVVTL 855
Query: 60 YFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLY 119
+++ PELL + + ++DMWS GC+L ++ K P G + Q+ I ++LGT +
Sbjct: 854 WYRAPELLFGSKTHSTAIDMWSAGCILGELLGHK-PLMPGRSDLQQIELIMELLGTPNDT 678
Query: 120 DY--------IDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRY 171
+ +++ ++ P +N++ RH+ W +S + L+ L Y
Sbjct: 677 IWPGFSQLPAFEQFTLKKQP-YNNL--RHTFP-W-----------LSESGIRLLNGLFMY 543
Query: 172 DHQSRLTAREAMEHPYF 188
Q R TA + +EH YF
Sbjct: 542 HPQKRATAEDCLEHSYF 492
>01756
Length = 1858
Score = 71.2 bits (173), Expect = 3e-13, Method: Compositional matrix adjust.
Identities = 37/119 (31%), Positives = 64/119 (53%), Gaps = 4/119 (3%)
Frame = -3
Query: 1 MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPG----QEYNVRV 56
M +++ L Y H I+HRD+K N++I + L+L D+GLA + Y RV
Sbjct: 1403 MKQLMNGLYYIHRNKILHRDMKAANILITKQG-VLKLADFGLARAFSVNLRQPNRYTNRV 1227
Query: 57 ASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGT 115
+ +++ PELL+ + Y ++D W GC++A M + + P G +QL I ++ G+
Sbjct: 1226 VTLWYRPPELLLGDRNYSTAIDQWGAGCIMAEM-WTRNPIMQGTTEQNQLTLITQLCGS 1053
>15910
Length = 1361
Score = 68.9 bits (167), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 52/191 (27%), Positives = 86/191 (45%), Gaps = 2/191 (1%)
Frame = +2
Query: 3 EILKALDYCHSMGIMHRDVKPHNVMID--HEHRKLRLIDWGLAEFYHPGQEYNVRVASRY 60
+IL + Y H+ G++HRD+KP N++ + + KL+L D+GL+ P + + +
Sbjct: 488 DILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLADFGLSRIIEPEVQMSTVCGTPG 667
Query: 61 FKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYD 120
+ PE+L Y S+DMWS+G + ++ EPFF ++ ++Y
Sbjct: 668 YCAPEVL-KGDKYTPSVDMWSVGVIAYILLCGYEPFFAENEF--------------EMYR 802
Query: 121 YIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAR 180
I K + D + W +S A D + KLL D + RLTA
Sbjct: 803 KIIKGEYKFDEEY-----------WSE---------ISENAKDVVRKLLVIDPKKRLTAT 922
Query: 181 EAMEHPYFYTV 191
EA+ P+ V
Sbjct: 923 EALRLPWVKGV 955
>23319
Length = 2235
Score = 68.6 bits (166), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 42/120 (35%), Positives = 60/120 (50%), Gaps = 2/120 (1%)
Frame = +3
Query: 71 QMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLG--TEDLYDYIDKYNIE 128
+MY S+DMWS GC+ A + P F G+D+ DQL RI K+LG TED + + +
Sbjct: 21 KMYSTSIDMWSAGCIFAELANAGRPLFPGNDDDDQLKRIFKLLGTPTEDQWPGMTQL--- 191
Query: 129 LDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYF 188
P + H W++ V N + D L LL R++A EA++HPYF
Sbjct: 192 --PNYRMFPMYHVTTTWQQVVPKLNS-----KGRDLLQCLLVCCPSDRMSADEALQHPYF 350
>21079
Length = 878
Score = 67.0 bits (162), Expect = 7e-12, Method: Compositional matrix adjust.
Identities = 30/84 (35%), Positives = 50/84 (59%), Gaps = 1/84 (1%)
Frame = +1
Query: 3 EILKALDYCHSMGIMHRDVKPHNVM-IDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYF 61
+I + Y H+ I+H D+KP NV+ + ++++ID+GLA FY PG V + F
Sbjct: 151 QICSGVGYMHTQSILHLDLKPENVLCVSDNSNQIKIIDFGLARFYKPGDSLQVLFGTPEF 330
Query: 62 KGPELLVDYQMYDYSLDMWSLGCM 85
PE +V+Y +++ DMWS+G +
Sbjct: 331 IAPE-VVNYDEINFTTDMWSIGVI 399
>12721
Length = 821
Score = 61.6 bits (148), Expect = 3e-10, Method: Compositional matrix adjust.
Identities = 33/95 (34%), Positives = 57/95 (60%), Gaps = 1/95 (1%)
Frame = +1
Query: 5 LKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGL-AEFYHPGQEYNVRVASRYFKG 63
LKAL + H+ G++HRD+K ++++ H+ K++L D+G A+ Q+ V + Y+
Sbjct: 403 LKALAFLHANGVIHRDIKSDSILLSHDG-KVKLXDFGFCAQVTQDLQKRKSLVGTPYWMA 579
Query: 64 PELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFH 98
PE++ Y +D+WSLG M+ MI + PFF+
Sbjct: 580 PEVISRLP-YGPEVDIWSLGIMVMEMIDAEPPFFN 681
>28638
Length = 1458
Score = 60.1 bits (144), Expect = 9e-10, Method: Compositional matrix adjust.
Identities = 28/77 (36%), Positives = 49/77 (63%), Gaps = 1/77 (1%)
Frame = -1
Query: 14 MGIMHRDVKPHNVMIDHEHRK-LRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQM 72
M I+H D+KP N+++ + R ++++D+G + GQ + SR+++ PE+L+
Sbjct: 774 MNIIHCDLKPENILLCNPKRSAIKIVDFGSS--CQLGQRIYQYIQSRFYRSPEVLLGVP- 604
Query: 73 YDYSLDMWSLGCMLASM 89
YD ++DMWSLGC+L M
Sbjct: 603 YDLAIDMWSLGCILVEM 553
Score = 32.3 bits (72), Expect = 0.18, Method: Compositional matrix adjust.
Identities = 32/142 (22%), Positives = 60/142 (42%), Gaps = 32/142 (22%)
Frame = -2
Query: 79 MWSLGCMLASMIFRK----EPFFHGHDNYDQLVRIAKVLG------------TEDLYDYI 122
W L C ++ + + P F G + +DQ+++I +VLG T +D +
Sbjct: 599 TWPLTCGXWAVYWWRCTXGNPLFAGSNEFDQMMKIVEVLGVPPRHILDQAQKTRKYFDLL 420
Query: 123 -------------DKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLL 169
KY + +++LG R + E H V+ + L F D +L
Sbjct: 419 PDGTYAPKKPRDNKKYKSPSSRKLHEVLGAEKGGPGGRRM-GEPGHTVA-DYLKFKDLIL 246
Query: 170 R---YDHQSRLTAREAMEHPYF 188
R +D ++R++ A++H +F
Sbjct: 245 RMLDFDPKTRISPYYALQHNFF 180
>01392
Length = 1806
Score = 59.3 bits (142), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 55/199 (27%), Positives = 84/199 (42%), Gaps = 12/199 (6%)
Frame = -1
Query: 4 ILKALDYCHSMGIMHRDVKPHNVMIDH--EHRKLRLIDWGLAEFYH------PGQEYNVR 55
I +ALD+ HS GI HRD+KP N++ +H + +++ D+ LA E
Sbjct: 1764 IARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGISCDGDGTKTPELLTP 1585
Query: 56 VASRYFKGPEL----LVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAK 111
V S + PE+ + D YD D+WSLG +L M+ PF Y Q
Sbjct: 1584 VGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILYIMLCGYPPF------YGQCGEDCG 1423
Query: 112 VLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRY 171
E +D D FN I H + S+ +S A D + LL
Sbjct: 1422 WNRGEACHDCQDML-------FNSIQDGHYK------FPSQEWTSISSSAKDLIRHLLVR 1282
Query: 172 DHQSRLTAREAMEHPYFYT 190
+ + R +A + ++HP+ T
Sbjct: 1281 EPRKRYSAADVLKHPWICT 1225
>26560
Length = 398
Score = 58.9 bits (141), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 32/94 (34%), Positives = 56/94 (59%)
Frame = -1
Query: 3 EILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFK 62
E++ L++ HS +++RD+KP N+++D E+ +R+ D GLA + + + V + +
Sbjct: 332 EVMLGLEHMHSRFVVYRDLKPANILLD-ENGHVRISDLGLACDFSKKRPH-ASVGTHGYM 159
Query: 63 GPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPF 96
PE+L+ Q YD S D +S GCML ++ PF
Sbjct: 158 APEVLMKGQSYDSSADWFSFGCMLYKLLKGHSPF 57
>14420
Length = 528
Score = 57.8 bits (138), Expect = 5e-09, Method: Compositional matrix adjust.
Identities = 30/97 (30%), Positives = 55/97 (56%), Gaps = 1/97 (1%)
Frame = +2
Query: 3 EILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQ-EYNVRVASRYF 61
E L+AL++ H ++HRD+K N+++ + ++L D+G P Q + + V + Y+
Sbjct: 221 ECLQALEFLHENQVIHRDIKSDNILLGMDG-SVKLTDFGFCAQLSPEQSKRSTMVGTPYW 397
Query: 62 KGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFH 98
PE++ Q Y ++D+WSLG M MI + P+ +
Sbjct: 398 MAPEVVTRKQ-YGPTVDIWSLGVMCIEMIEGEPPYLN 505
>01966
Length = 1735
Score = 57.0 bits (136), Expect = 7e-09, Method: Compositional matrix adjust.
Identities = 32/119 (26%), Positives = 58/119 (48%)
Frame = -3
Query: 73 YDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPR 132
Y +D+WS+G + A M+ R P F G DQL +I +++GT + + + + P
Sbjct: 1175 YSTPVDVWSIGTIFADMLIRT-PIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKL---PA 1008
Query: 133 FNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTV 191
FN + W+ SE + LD +++ L+ D R++ ++ ++H YF V
Sbjct: 1007 FNGMF-----PLWKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYFLNV 846
Score = 55.5 bits (132), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 25/86 (29%), Positives = 52/86 (60%), Gaps = 1/86 (1%)
Frame = -1
Query: 1 MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAE-FYHPGQEYNVRVASR 59
+++I+ +++CH I+HRD+KP N++I+H +++ D+G+A F P + Y V +
Sbjct: 1390 VFQIVTGINFCHQRRIVHRDLKPQNLLINHTG-AIKIADFGMARTFALPVRAYTHEVVTL 1214
Query: 60 YFKGPELLVDYQMYDYSLDMWSLGCM 85
+++ PE+L+ Q + W+ G +
Sbjct: 1213 WYRAPEILMGPQ---STPPXWTCGAL 1145
>03294
Length = 1684
Score = 55.5 bits (132), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 31/115 (26%), Positives = 57/115 (49%)
Frame = -1
Query: 77 LDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDI 136
+D+WS+G + A M+ R P F G DQL +I +++GT + + + + P FN +
Sbjct: 1672 VDVWSIGTIFADMLIRT-PIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKL---PAFNGM 1505
Query: 137 LGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTV 191
W+ SE + LD +++ L+ D R++ ++ ++H YF V
Sbjct: 1504 F-----PLWKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYFLNV 1355
>26711
Length = 405
Score = 55.1 bits (131), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 28/95 (29%), Positives = 53/95 (55%), Gaps = 1/95 (1%)
Frame = -2
Query: 3 EILKALDYCHSMGIMHRDVKPHNVMIDHEH-RKLRLIDWGLAEFYHPGQEYNVRVASRYF 61
++L L + H+ G++H D+KP N+++ + ++LID+GLA +P QE + + F
Sbjct: 392 QVLDILQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARKLYPPQETFLNHGTPGF 213
Query: 62 KGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPF 96
PE L D + + D+W +G + ++ + PF
Sbjct: 212 TSPEAL-DVKPISTASDVWGVGVLAYILLSGQSPF 111
>12786
Length = 460
Score = 55.1 bits (131), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 38/130 (29%), Positives = 66/130 (50%), Gaps = 22/130 (16%)
Frame = -3
Query: 3 EILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEY---NVRVASR 59
E+L+A+ H+ G++H D+KP N M+ + L+LID+G+A + + RV +
Sbjct: 386 EMLRAVKALHNEGVIHSDLKPANFMLVAGN--LKLIDFGIANTLQQDKTSVLKDSRVGTP 213
Query: 60 YFKGPELLV-------DYQMYD--------YSL----DMWSLGCMLASMIFRKEPFFHGH 100
+ PE ++ D M + Y + D+WSLGC+L +M++ + PF H
Sbjct: 212 SYMSPEAIMAACDDSADDSMEEDGHRTKPKYKVGVRSDVWSLGCILYNMVYGRTPFQHIK 33
Query: 101 DNYDQLVRIA 110
+N +L I
Sbjct: 32 NNMGKLQAIT 3
>13212
Length = 1067
Score = 54.7 bits (130), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 50/194 (25%), Positives = 82/194 (42%), Gaps = 7/194 (3%)
Frame = -1
Query: 2 YEILKALDYCHSMGIMHRDVKPHNVM--IDHEHRKLRLIDWGL-AEFYHPGQEYNVRVAS 58
+E+ ALD+ H ++HRD+K NV+ ID E ++L D+G+ A+ Q+ + + +
Sbjct: 959 HEMCMALDFLHRHHVIHRDIKAGNVLLTIDGE---VKLADFGVSAKNTQTQQKRDTFIGT 789
Query: 59 RYFKGPELLVDYQM----YDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLG 114
Y+ PE+++ + YD+ D+WSLG L + P H L++I K
Sbjct: 788 PYWMAPEVVLCETLKDTPYDFKADIWSLGVTLIEFAQIEPPNKEMH-PMRVLIKIHK--- 621
Query: 115 TEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQ 174
+D K+W + DF+ K L D
Sbjct: 620 -------------------SDPPTLEKPKKWTKLFK------------DFIAKCLVKDPN 534
Query: 175 SRLTAREAMEHPYF 188
R TA E +EHP+
Sbjct: 533 LRPTAAELLEHPFM 492
>30755
Length = 1137
Score = 54.3 bits (129), Expect = 4e-08, Method: Compositional matrix adjust.
Identities = 35/112 (31%), Positives = 60/112 (53%), Gaps = 2/112 (1%)
Frame = +2
Query: 3 EILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLA-EFYHPGQEYNVRVASRYF 61
EI+ AL Y HS GI++RD+K N+++D + +++ D+GL E G+ + +
Sbjct: 56 EIISALGYLHSQGIIYRDLKLENLLLDKDGH-IKVADFGLCKEDITYGRTTKTFCGTPEY 232
Query: 62 KGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFH-GHDNYDQLVRIAKV 112
PE+L D Y ++D W G ++ MI + PF++ HD L+ + V
Sbjct: 233 LAPEVLDDND-YGRAVDWWGTGVVMYEMICGRLPFYNRDHDVLFTLILVEDV 385
>18287
Length = 678
Score = 54.3 bits (129), Expect = 5e-08, Method: Compositional matrix adjust.
Identities = 35/119 (29%), Positives = 63/119 (52%), Gaps = 3/119 (2%)
Frame = -3
Query: 73 YDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGT---EDLYDYIDKYNIEL 129
YDYS+D+WS+GC+ A ++ R+ F QL I ++GT ED+ +
Sbjct: 673 YDYSIDIWSVGCIFAELLSRRI-LFQAQGPVQQLDMIINLVGTPRPEDMERACEGAR--- 506
Query: 130 DPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYF 188
N IL + R++ +++ + H + EA+ L ++L + ++R++A EA+ HPY
Sbjct: 505 ----NHILNQPFRRQNLLTLYNLSPH-ATHEAVRLLTRMLILNPKNRISAEEALSHPYL 344
>19761
Length = 473
Score = 53.9 bits (128), Expect = 6e-08, Method: Compositional matrix adjust.
Identities = 37/121 (30%), Positives = 60/121 (49%), Gaps = 3/121 (2%)
Frame = -3
Query: 1 MYEILKALDYCHSMG--IMHRDVKPHNVMIDHEHRKLRLIDWGLA-EFYHPGQEYNVRVA 57
+ + AL+Y H+ I+HRD+KP N+ + E +RL D GLA + P +V
Sbjct: 405 LMQTASALNYMHTHTPVILHRDLKPQNIYVT-EKGDVRLGDLGLARKLTGPADFATSQVG 229
Query: 58 SRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTED 117
+ + PE+L Q Y+ D+WSLGC+ + +K G D + + +V+G
Sbjct: 228 TIMYLSPEIL-SQQPYNSKSDIWSLGCVFYDITGKK-----GSDEMGVMFLLVQVMGGRK 67
Query: 118 L 118
L
Sbjct: 66 L 64
>00300
Length = 2318
Score = 52.4 bits (124), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 32/115 (27%), Positives = 60/115 (52%), Gaps = 7/115 (6%)
Frame = -1
Query: 3 EILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLA-----EFYHPGQEYNVRVA 57
EI+ A+++ H I+HRD+K N+ + + ++L D+G + PG+ +N+ V
Sbjct: 1343 EIVLAVNHLHENSIVHRDIKGANIFLT-SNGHVKLGDFGCSVKLKSHTTMPGEFHNL-VG 1170
Query: 58 SRYFKGPELLV--DYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIA 110
+ + PE+ D Y + D+WSLGC++ M K P+ +NY + ++
Sbjct: 1169 TTAYMAPEVFTQNDQGGYGRAADIWSLGCVVIEMATGKRPWHDLDNNYQIMYKVG 1005
>18921
Length = 697
Score = 51.6 bits (122), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 31/99 (31%), Positives = 51/99 (51%), Gaps = 1/99 (1%)
Frame = +2
Query: 1 MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLA-EFYHPGQEYNVRVASR 59
+Y LK L Y HS +HRD+K N+++++E +L D+G+A + + N + +
Sbjct: 335 LYYTLKGLXYLHSRRKIHRDIKAGNILLNNEGHA-KLADFGVAGQLTDTMAKRNTVIGTP 511
Query: 60 YFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFH 98
Y+ PE++ + YD D+WSLG M K P
Sbjct: 512 YWMAPEVIQEIG-YDCVADIWSLGITALEMAEGKPPVME 625
>18484
Length = 635
Score = 51.2 bits (121), Expect = 4e-07, Method: Compositional matrix adjust.
Identities = 33/100 (33%), Positives = 53/100 (53%), Gaps = 6/100 (6%)
Frame = +1
Query: 3 EILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFK 62
EI L + H GI++RD+K NVM+D E +++ D+G+ + G +R F
Sbjct: 67 EIAVGLFFLHDQGIIYRDLKLDNVMLDSEGH-IKIADFGMCKEGMTGD-----ATTRTFC 228
Query: 63 G------PELLVDYQMYDYSLDMWSLGCMLASMIFRKEPF 96
G PE+++ YQ Y S+D W+ G +L M+ + PF
Sbjct: 229 GTPDYIAPEIVL-YQPYSKSVDWWAYGVLLFEMLAGQPPF 345
>09606
Length = 1300
Score = 50.4 bits (119), Expect = 7e-07, Method: Compositional matrix adjust.
Identities = 51/210 (24%), Positives = 86/210 (40%), Gaps = 25/210 (11%)
Frame = -3
Query: 4 ILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAE------------FYHPGQE 51
++ L Y HS+GI+ D++P V++D L+ D+GL++ F G +
Sbjct: 806 LVTGLHYIHSLGILFHDLRPSKVLLD-TSGVLKFADFGLSKVEGENLEELFFKFAEAGDQ 630
Query: 52 YNVRVASRYFK-----------GPELLVDYQMYDYSL--DMWSLGCMLASMIFRKEPFFH 98
+N++ A K PE+ +Q + S+ D+W+LGC+ M F P F
Sbjct: 629 WNIQSAEEMMKQVPTSGSPTYMAPEV---FQGAEPSIMSDLWALGCVFYEM-FSGHPPFL 462
Query: 99 GHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVS 158
G + YD + KVL E + + P S
Sbjct: 461 G-ETYD--ITKDKVLNKEFPLPKVKGSRLSAKP--------------------------S 369
Query: 159 PEALDFLDKLLRYDHQSRLTAREAMEHPYF 188
PE L+ L+ LL+ D RL+ ++H ++
Sbjct: 368 PEFLNLLESLLQKDSTRRLSWASLVKHAFW 279
>13592
Length = 980
Score = 50.4 bits (119), Expect = 7e-07, Method: Compositional matrix adjust.
Identities = 44/192 (22%), Positives = 78/192 (40%), Gaps = 7/192 (3%)
Frame = +2
Query: 3 EILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYH-----PGQEYNVRVA 57
++L + H GI+HRD+K N+ + L+L D+G A PG E V
Sbjct: 305 QLLSGVAELHKHGIVHRDIKTANIFLVDGSNSLKLGDFGSAVKIQAHTTVPG-ELQGYVG 481
Query: 58 SRYFKGPELLVDYQMYDYS--LDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGT 115
++ + PE+ + D+WS+GC++ M K P+ N+ + ++ +G
Sbjct: 482 TQAYMAPEVFTKTNSDGHGRLADIWSVGCVVVEMASGKRPWAQFDSNFQIMFKVG--MGE 655
Query: 116 EDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQS 175
+ P+ + L S E DF+D L++D +
Sbjct: 656 K--------------PQAPESL--------------------SQEGHDFIDHCLQHDPKQ 733
Query: 176 RLTAREAMEHPY 187
RL+A E +E +
Sbjct: 734 RLSAIELLEQNF 769
>18401
Length = 463
Score = 50.4 bits (119), Expect = 8e-07, Method: Compositional matrix adjust.
Identities = 35/143 (24%), Positives = 74/143 (51%), Gaps = 10/143 (6%)
Frame = -3
Query: 56 VASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGT 115
V++R+++ PE++++ + + D+WS+GC++ ++ F HDN + L + ++LG+
Sbjct: 449 VSTRHYRAPEVILELG-WSHPCDVWSVGCIMFE-LYTGYTLFQTHDNKEHLAMMERILGS 276
Query: 116 EDLYDYIDKYNIE-------LDPRFNDILGRHSRKRWE---RFVHSENQHLVSPEALDFL 165
Y K + LD + R+ R+ + R+V + ++ + D +
Sbjct: 275 LP-YRMAKKTKKQKYFHHGRLDVPERSSMARYVRENTKPLLRYV-KDRENKDHQQLFDLM 102
Query: 166 DKLLRYDHQSRLTAREAMEHPYF 188
KLL Y+ SR + +A++HP+F
Sbjct: 101 KKLLAYEASSRYSLLQALQHPFF 33
>00638
Length = 1595
Score = 49.7 bits (117), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 19/23 (82%), Positives = 23/23 (100%)
Frame = +2
Query: 1 MYEILKALDYCHSMGIMHRDVKP 23
+YE++KALD+CHSMGIMHRDVKP
Sbjct: 434 LYELMKALDFCHSMGIMHRDVKP 502
>19094
Length = 898
Score = 49.3 bits (116), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 29/90 (32%), Positives = 49/90 (54%), Gaps = 1/90 (1%)
Frame = +1
Query: 1 MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLA-EFYHPGQEYNVRVASR 59
+Y LK L Y HS +HRD+K N+++++E +L D+G+A + + N + +
Sbjct: 76 LYYTLKGL*YLHSRRKIHRDIKAGNILLNNEGHA-KLADFGVAGQLTDTMAKRNTVIGTP 252
Query: 60 YFKGPELLVDYQMYDYSLDMWSLGCMLASM 89
Y+ PE++ + YD D+WSLG M
Sbjct: 253 YWMAPEVIQEIG-YDCVADIWSLGITALEM 339
>31885
Length = 529
Score = 48.9 bits (115), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 27/100 (27%), Positives = 51/100 (51%), Gaps = 4/100 (4%)
Frame = -2
Query: 1 MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRY 60
+ ++ LDY S I+HRD+KP N+++D E + D+ +A + +R
Sbjct: 354 LCQLALVLDYLRSQKIVHRDIKPDNILLD-EQGHCHVTDFNIATQLEDDELATSTSGTRP 178
Query: 61 FKGPEL----LVDYQMYDYSLDMWSLGCMLASMIFRKEPF 96
+ PE+ + + + Y + +D WSLG L ++ ++ PF
Sbjct: 177 YMAPEVYGVAINERRGYGFPVDWWSLGVSLFELLKKRRPF 58
>13078
Length = 773
Score = 48.1 bits (113), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 37/126 (29%), Positives = 61/126 (48%), Gaps = 14/126 (11%)
Frame = -1
Query: 77 LDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDK-------YNIEL 129
D+WS+GC++ ++ F HDN + L + ++LG+ Y K Y+ L
Sbjct: 734 CDVWSIGCIMFE-LYTGYTLFQTHDNKEHLAMMERILGSLP-YRMAKKTKKQKYFYHGRL 561
Query: 130 DPRFNDILGRHSR---KRWERFV----HSENQHLVSPEALDFLDKLLRYDHQSRLTAREA 182
D GR+ R K R+V + ++Q L D +DK+L Y+ +R + R+A
Sbjct: 560 DWDEKSSAGRYVRDNVKPLRRYVKDPDNEDHQQL-----FDLMDKMLSYEVSTRYSLRQA 396
Query: 183 MEHPYF 188
M HP+F
Sbjct: 395 MRHPFF 378
>21433
Length = 590
Score = 47.0 bits (110), Expect = 8e-06, Method: Compositional matrix adjust.
Identities = 42/171 (24%), Positives = 75/171 (43%)
Frame = +2
Query: 1 MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRY 60
+Y++ AL+YCH ++HRD+KP N+++ L++ D+G + + P +
Sbjct: 185 IYQLSSALEYCHYRKVIHRDIKPENLLLG-LKGDLKIADFGWS-VHAPSSRRTTMCGTLD 358
Query: 61 FKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYD 120
+ PE +V+ + +D ++D+WSLG + Y+ LV GT L
Sbjct: 359 YLPPE-MVEGKTHDENVDLWSLGVLC----------------YEFLV------GTPPLRP 469
Query: 121 YIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRY 171
+ PR+ S + +V+P A D + KLLR+
Sbjct: 470 SPTRPPTPASPRWT----------------SGSPSIVTPGARDLISKLLRH 574
>13066
Length = 551
Score = 44.7 bits (104), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 27/87 (31%), Positives = 43/87 (49%), Gaps = 4/87 (4%)
Frame = +3
Query: 1 MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGL--AEFYHPGQEYNVR--V 56
Y++ AL+Y HS + HRD+K N+++ H ++L D+G A G++Y R
Sbjct: 294 FYQMTTALNYLHSYDVAHRDLKCENILLS-SHFNVKLADFGFACACITESGEKYMSRTYC 470
Query: 57 ASRYFKGPELLVDYQMYDYSLDMWSLG 83
S + PE++ D WSLG
Sbjct: 471 GSAAYAAPEIVYGAPYAPKVADAWSLG 551
>27405
Length = 532
Score = 44.7 bits (104), Expect = 4e-05, Method: Compositional matrix adjust.
Identities = 25/76 (32%), Positives = 47/76 (61%)
Frame = -3
Query: 3 EILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFK 62
E++ L++ HS +++RD+KP N+++D E+ +R+ D GLA + ++ + V + +
Sbjct: 230 EVMLGLEHMHSRFVVYRDLKPANILLD-ENGHVRISDLGLACDFSK-KKPHASVGTHGYM 57
Query: 63 GPELLVDYQMYDYSLD 78
PE+L+ Q YD S D
Sbjct: 56 APEVLMKGQAYDSSAD 9
>04852
Length = 1462
Score = 44.3 bits (103), Expect = 4e-05, Method: Compositional matrix adjust.
Identities = 27/88 (30%), Positives = 45/88 (51%), Gaps = 3/88 (3%)
Frame = +1
Query: 2 YEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRY- 60
++I + +++ S +HRD+ NV++ EH L++ D+GL+ G Y R R
Sbjct: 346 FQIARGMEFLASRKCIHRDLAARNVLVTEEH-VLKIADFGLS---RTGDYYKKRSGGRLP 513
Query: 61 --FKGPELLVDYQMYDYSLDMWSLGCML 86
+ PE L D + Y D+WS G +L
Sbjct: 514 VKWMAPEALFDMR-YTTKSDVWSFGVVL 594
>03240
Length = 1683
Score = 43.1 bits (100), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 33/140 (23%), Positives = 53/140 (37%), Gaps = 45/140 (32%)
Frame = -3
Query: 3 EILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGL-------------------- 42
E+++A++ H MG +HRD+KP N++ID ++L D+GL
Sbjct: 967 ELVQAIESVHRMGFIHRDIKPDNILIDRNGH-IKLTDFGLCTGFRWTHNSKYYQRDGTHA 791
Query: 43 ----------------AEFYHPGQEYNVR---------VASRYFKGPELLVDYQMYDYSL 77
E P + R V + + PE+L Y
Sbjct: 790 RQDSMEVKCQLDEQCQCEILKPLERRRKREQRCLAHSLVGTPNYIAPEVLSRLGGYTSVC 611
Query: 78 DMWSLGCMLASMIFRKEPFF 97
D WS+G +L M+ PF+
Sbjct: 610 DWWSVGVILFEMLVGHPPFY 551
>11185
Length = 473
Score = 42.4 bits (98), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 29/112 (25%), Positives = 52/112 (46%), Gaps = 25/112 (22%)
Frame = +1
Query: 4 ILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAE------------FYHPGQE 51
++ L Y HS+GI+ D++P V++D L+ D+GL++ F G +
Sbjct: 28 LVTGLHYIHSLGILFHDLRPSKVLLDTSGV-LKFADFGLSKVEGENLEELFFKFAEAGDQ 204
Query: 52 YNVRVASRYFK-----------GPELLVDYQMYDYSL--DMWSLGCMLASMI 90
+N++ A K PE+ +Q + S+ D+W+LGC+ M
Sbjct: 205 WNIQSAEEMMKQVPTSGSPTYMAPEV---FQGAEPSIMSDLWALGCVFYEMF 351
>00715
Length = 1788
Score = 41.6 bits (96), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 32/117 (27%), Positives = 50/117 (42%), Gaps = 23/117 (19%)
Frame = +1
Query: 3 EILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHP-------------- 48
++ + L Y HS+ I+H D+KP N ++ + KLR+ D+G P
Sbjct: 262 QMARGLHYLHSINIVHLDLKPANCLLTRD-LKLRIADFGCCHQLTPTGLDMGEREGGMAG 438
Query: 49 ---------GQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPF 96
G N + ++ PELL Q S D++SLG L M R+ P+
Sbjct: 439 NELELTPVQGAWKNELAGTLAYRAPELLKGLQPSVRS-DVYSLGITLWQMCTRQGPY 606
>17975
Length = 449
Score = 40.8 bits (94), Expect = 6e-04, Method: Compositional matrix adjust.
Identities = 15/41 (36%), Positives = 29/41 (70%)
Frame = +3
Query: 3 EILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLA 43
+I++A+ YCH + ++HRD+KP NV+ + ++L D+G +
Sbjct: 291 QIVEAISYCHKLHVVHRDLKPENVVFFEKPGLVKLTDFGFS 413
>05084
Length = 1324
Score = 38.5 bits (88), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 25/91 (27%), Positives = 39/91 (42%), Gaps = 1/91 (1%)
Frame = +2
Query: 99 GHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDI-LGRHSRKRWERFVHSENQHLV 157
G DQLV I KVLGT + E++P +++ + W +
Sbjct: 8 GDSGVDQLVEIIKVLGTPT-----REQIREMNPNYSEFKFPQIKAHPWTKVFRPRT---- 160
Query: 158 SPEALDFLDKLLRYDHQSRLTAREAMEHPYF 188
PEA+ + +LL Y +R+ EA H +F
Sbjct: 161 PPEAIQLVSRLLEYTPSARIQPMEACAHAFF 253
>14116
Length = 1017
Score = 38.1 bits (87), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 24/95 (25%), Positives = 47/95 (49%), Gaps = 5/95 (5%)
Frame = -1
Query: 3 EILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLA-----EFYHPGQEYNVRVA 57
+I + +DY + +HRD+ N M+D E +++ D+GLA + Y+ + ++
Sbjct: 297 DIARGMDYLAGLKFVHRDLAARNCMLD-EDFHVKVADFGLARDIYEKEYYSSENKKAKLP 121
Query: 58 SRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFR 92
++ L + YD D+WS G +L ++ R
Sbjct: 120 VKWMALESL--EKGNYDSKTDVWSYGVVLWELLTR 22
>01718
Length = 959
Score = 38.1 bits (87), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 28/92 (30%), Positives = 47/92 (51%), Gaps = 5/92 (5%)
Frame = +3
Query: 6 KALDYCHSMGIMHRDVKPHNVMIDHEHR---KLRLIDWGLA-EFYHP-GQEYNVRVASRY 60
+ LDY HS +HRD+ N++I E + D+GLA + P +E V S Y
Sbjct: 468 RGLDYLHSTRFIHRDLTSKNILIRREDNHGYHAVIADFGLATKIPDPLDKEKLPTVGSPY 647
Query: 61 FKGPELLVDYQMYDYSLDMWSLGCMLASMIFR 92
+ PE+L + Y+ D++S+G ++ + R
Sbjct: 648 WMAPEVL-NGHFYNERADLFSVGIIMCEITAR 740
>26009
Length = 886
Score = 38.1 bits (87), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 14/28 (50%), Positives = 22/28 (78%)
Frame = +3
Query: 1 MYEILKALDYCHSMGIMHRDVKPHNVMI 28
M +++ ALD+ HS ++HRD+KP NV+I
Sbjct: 729 MKQLVSALDFMHSKQLVHRDIKPENVLI 812
>00392
Length = 668
Score = 37.7 bits (86), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 25/87 (28%), Positives = 48/87 (55%), Gaps = 3/87 (3%)
Frame = +3
Query: 3 EILKALDYCHSMG--IMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRY 60
++LK L + H+ ++HRD+K N+ I +++ D GLA + +V + +
Sbjct: 270 QVLKGLYFLHTRTPPVIHRDLKCDNIFITGPTGSVKIGDLGLATLKNQSFAKSV-IGTPE 446
Query: 61 FKGPELLVDYQMYDYSLDMWSLG-CML 86
F PE+ ++ YD ++D+++ G CML
Sbjct: 447 FMAPEMYEEH--YDEAVDVYAFGMCML 521
>31489
Length = 329
Score = 36.2 bits (82), Expect = 0.014, Method: Compositional matrix adjust.
Identities = 13/27 (48%), Positives = 21/27 (77%)
Frame = +3
Query: 1 MYEILKALDYCHSMGIMHRDVKPHNVM 27
+Y+IL+ L Y HS ++HRD+KP N++
Sbjct: 183 LYQILRGLKYIHSANVVHRDLKPSNLL 263
>37602
Length = 804
Score = 35.0 bits (79), Expect = 0.031, Method: Compositional matrix adjust.
Identities = 20/59 (33%), Positives = 29/59 (49%)
Frame = -1
Query: 3 EILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYF 61
E LK L Y H G MHRD+K N+++ E D LA+F+ ++ V + F
Sbjct: 195 ETLKGLHYLHRRGKMHRDIKGANILLTEEG------DVKLADFWRVSSNHSHNVQKKVF 37
>02638
Length = 1490
Score = 35.0 bits (79), Expect = 0.033, Method: Compositional matrix adjust.
Identities = 31/128 (24%), Positives = 52/128 (40%)
Frame = +1
Query: 61 FKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYD 120
F PE+L + Y + D+WS+GC++ M + P ++ HD + L I K+ +
Sbjct: 34 FMAPEVL-RGESYGRACDVWSVGCVMIEMCTCRPP-WNSHDISNHLALIFKIASS----- 192
Query: 121 YIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAR 180
+D I EN +SP D + + L D R +A+
Sbjct: 193 -VDPPPI-----------------------PEN---MSPPVRDLMLRCLEQDSDFRPSAK 291
Query: 181 EAMEHPYF 188
+ + HP F
Sbjct: 292 DLLMHPLF 315
>18481
Length = 437
Score = 34.7 bits (78), Expect = 0.036, Method: Compositional matrix adjust.
Identities = 19/51 (37%), Positives = 31/51 (60%), Gaps = 3/51 (5%)
Frame = -1
Query: 3 EILKALDYCHSMGIMHRDVKPHNVMID---HEHRKLRLIDWGLAEFYHPGQ 50
++L L++ H +HRD+KP N ++ H HR L +ID+GL++ Y Q
Sbjct: 173 QLLSRLEFIHQKCFIHRDLKPDNFLMGLGRHCHR-LYIIDFGLSKRYKDTQ 24
>27546
Length = 426
Score = 34.3 bits (77), Expect = 0.046, Method: Compositional matrix adjust.
Identities = 15/45 (33%), Positives = 28/45 (62%)
Frame = -1
Query: 1 MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEF 45
+++ KAL Y HS I HRD+K N+++ + +++ D+G A +
Sbjct: 162 FFQMAKALQYLHSHDIAHRDLKCENILLS-KRLNVKIADFGFARY 31
>06358
Length = 1517
Score = 33.9 bits (76), Expect = 0.068, Method: Compositional matrix adjust.
Identities = 42/162 (25%), Positives = 76/162 (46%), Gaps = 31/162 (19%)
Frame = +3
Query: 1 MYEILKALDYCHS-MGIMHRDVKPHNVMIDHEHRKLRLIDWGLA--EFY----------- 46
+ ++ +AL + H+ +MHR+V P +M+ +L W LA EF
Sbjct: 378 LLQVTEALGFLHNDAKMMHRNVCPEAIMLT------KLGSWKLAGYEFCVRSSDPQSTDP 539
Query: 47 -HPGQEYNVRVASRY-----FKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGH 100
+P E+ +A F PE ++ Q S DM+SLG ++ S+ + +P F +
Sbjct: 540 SYPFYEWRSDIAPVTQPHLDFMAPEYVLTMQCGTGS-DMFSLGLLVYSVFAKGKPLFECN 716
Query: 101 -------DNYDQL--VRIAKVLGT--EDLYDYIDKYNIELDP 131
N ++L +R++ +LG EDL D++ K + ++P
Sbjct: 717 GELSAFKSNAEELRHMRVS-LLGVVPEDLRDHV-KLLLNIEP 836
>29590
Length = 320
Score = 33.5 bits (75), Expect = 0.088, Method: Compositional matrix adjust.
Identities = 18/58 (31%), Positives = 28/58 (48%)
Frame = +3
Query: 39 DWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPF 96
D G A + G++ + + + PE+L DY+ DMWSLG + M+ PF
Sbjct: 6 DLGFACLTNTGEDIRDIIGTPDYVAPEVL-DYEPLSIQTDMWSLGVLSYVMLTACSPF 176
>15931
Length = 447
Score = 33.1 bits (74), Expect = 0.10, Method: Compositional matrix adjust.
Identities = 12/29 (41%), Positives = 20/29 (68%)
Frame = +1
Query: 160 EALDFLDKLLRYDHQSRLTAREAMEHPYF 188
+ D +DK+L Y+ +R + R+AM HP+F
Sbjct: 70 QLFDLMDKMLSYEVSTRYSLRQAMRHPFF 156
>11801
Length = 743
Score = 32.7 bits (73), Expect = 0.13, Method: Compositional matrix adjust.
Identities = 26/93 (27%), Positives = 49/93 (52%), Gaps = 3/93 (3%)
Frame = -1
Query: 79 MWSLGCMLASMIFRKEPFFHGHDNYDQLVR---IAKVLGTEDLYDYIDKYNIELDPRFND 135
++S G L +++ +K P YDQL R +AKV+ + D++ I+LDP+++
Sbjct: 302 VFSGGTALRTLL-KKFPVTSSSIPYDQLQRRCSVAKVVSETSCCKFGDQF-IKLDPQYDY 129
Query: 136 ILGRHSRKRWERFVHSENQHLVSPEALDFLDKL 168
+ ++S + R+ QH+ +AL F D +
Sbjct: 128 RVAKYSYLQSYRYFDDHKQHIR--QALMFNDTI 36
>26909
Length = 394
Score = 32.7 bits (73), Expect = 0.14, Method: Compositional matrix adjust.
Identities = 29/109 (26%), Positives = 43/109 (39%), Gaps = 10/109 (9%)
Frame = +2
Query: 90 IFRKEPFFHGHD---------NYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRH 140
+ EP FH ++DQL RI V+G D+ D + + R
Sbjct: 14 LLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFPQEKDWEDIRRMPEHQQLTKDFKRS 193
Query: 141 SRKRWERFVHSENQHL-VSPEALDFLDKLLRYDHQSRLTAREAMEHPYF 188
S + E + +A L KLL D R+T+ +AM+ PYF
Sbjct: 194 SYVNCNLMKYMEKHKVKADSKAFHLLQKLLTMDPVKRITSEQAMKDPYF 340
>14104
Length = 573
Score = 31.6 bits (70), Expect = 0.29, Method: Compositional matrix adjust.
Identities = 11/31 (35%), Positives = 19/31 (61%)
Frame = +1
Query: 157 VSPEALDFLDKLLRYDHQSRLTAREAMEHPY 187
+P+A+ F+ L+ D RLT + ++HPY
Sbjct: 88 AAPQAMSFMQSCLKMDPAERLTCHQLLQHPY 180
>28157
Length = 400
Score = 31.6 bits (70), Expect = 0.31, Method: Compositional matrix adjust.
Identities = 15/44 (34%), Positives = 26/44 (59%), Gaps = 3/44 (6%)
Frame = +3
Query: 7 ALDYCHSM---GIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYH 47
++Y H M ++HRD+KP N+++ KL++ D+G A H
Sbjct: 252 GVEYLHGMKPKALIHRDLKPPNLLLIQCGTKLKICDFGTACDIH 383
>12672
Length = 773
Score = 31.2 bits (69), Expect = 0.43, Method: Compositional matrix adjust.
Identities = 23/88 (26%), Positives = 41/88 (46%), Gaps = 3/88 (3%)
Frame = +3
Query: 6 KALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPE 65
+ Y + G +HRD+K N+++D E+ ++ D+ G+ V+ AS
Sbjct: 24 SGIQYLNDNGHVHRDIKTANILLDSEYTA-KVGDFATVVSAPSGEGKTVQNASVVIGTAA 200
Query: 66 LLVDYQM-YDYS--LDMWSLGCMLASMI 90
L + +D S LD +S G +L +I
Sbjct: 201 YLAPEAIHFDVSTKLDSYSFGVVLLEVI 284
>21800
Length = 855
Score = 30.8 bits (68), Expect = 0.60, Method: Compositional matrix adjust.
Identities = 18/55 (32%), Positives = 31/55 (56%), Gaps = 6/55 (10%)
Frame = +2
Query: 1 MYEILKALDYCHS-MGIMHRDVKPHNVMI---DHEHRKLRL--IDWGLAEFYHPG 49
+ ++L+ L+Y H+ I+H D+KP N++I D+ RKL + +W PG
Sbjct: 650 IRQVLEGLNYLHAKCNIIHTDIKPENILICVDDNYIRKLAVDAFEWQRLGLKLPG 814
>27274
Length = 396
Score = 30.4 bits (67), Expect = 0.65, Method: Compositional matrix adjust.
Identities = 30/126 (23%), Positives = 50/126 (39%)
Frame = -1
Query: 63 GPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYI 122
G ELL Q + ++DMWSLG +L ++ PF Q+ R +
Sbjct: 381 GAELLRG-QQHGPTVDMWSLGILLHELLSGHVPF-EPERGSRQMARNMMAV--------- 235
Query: 123 DKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREA 182
+ I+ SR + +S DFL +L++ + RLT+++A
Sbjct: 234 ----------YAQIIRGSSRDVCDGLA-------LSTHGADFLRRLVQLEDTKRLTSQQA 106
Query: 183 MEHPYF 188
HP+
Sbjct: 105 FSHPWI 88
>35032
Length = 465
Score = 30.0 bits (66), Expect = 0.92, Method: Compositional matrix adjust.
Identities = 12/27 (44%), Positives = 16/27 (59%)
Frame = +3
Query: 163 DFLDKLLRYDHQSRLTAREAMEHPYFY 189
D + +LL YD RLT A+ HP+ Y
Sbjct: 147 DLVKRLLNYDPSKRLTPXXALAHPFLY 227
>37063
Length = 455
Score = 30.0 bits (66), Expect = 1.0, Method: Compositional matrix adjust.
Identities = 23/78 (29%), Positives = 36/78 (46%), Gaps = 12/78 (15%)
Frame = -2
Query: 21 VKPHNVMIDH--EHRKLRLIDWGLAEFYH------PGQEYNVRVASRYFKGPELLVDYQ- 71
+KP N++ +H E L++ D+ LA + E V S + PE++ +
Sbjct: 454 LKPENILCEHLDEVVPLKICDFDLASGINCDGDGTKTPELLTPVGSAEYMAPEVVDAWVG 275
Query: 72 ---MYDYSLDMWSLGCML 86
YD DMWSLG +L
Sbjct: 274 ESFSYDKRCDMWSLGIIL 221
>17932
Length = 597
Score = 30.0 bits (66), Expect = 1.0, Method: Compositional matrix adjust.
Identities = 17/35 (48%), Positives = 22/35 (62%)
Frame = -3
Query: 157 VSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTV 191
VS EA D + +LL D +SRL E +HP+F TV
Sbjct: 460 VSKEARDLISQLLS-DGKSRLGWPELQQHPFFKTV 359
>16350
Length = 1108
Score = 29.3 bits (64), Expect = 1.4, Method: Compositional matrix adjust.
Identities = 10/26 (38%), Positives = 18/26 (69%)
Frame = +3
Query: 163 DFLDKLLRYDHQSRLTAREAMEHPYF 188
DFL +L +D + R TA ++++HP+
Sbjct: 762 DFLAPMLEFDPEQRATAAQSLQHPWL 839
>19301
Length = 712
Score = 29.3 bits (64), Expect = 1.6, Method: Compositional matrix adjust.
Identities = 13/41 (31%), Positives = 27/41 (65%)
Frame = +2
Query: 3 EILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLA 43
+I ++Y HS I+HRD+K NV++ ++ +++ D+G +
Sbjct: 593 QIASGMNYLHSHKIIHRDLKSPNVLV-AKNDVVKISDFGTS 712
>29360
Length = 363
Score = 28.9 bits (63), Expect = 1.9, Method: Compositional matrix adjust.
Identities = 10/26 (38%), Positives = 18/26 (69%)
Frame = +3
Query: 3 EILKALDYCHSMGIMHRDVKPHNVMI 28
++L AL +G++H D+KP N+M+
Sbjct: 282 QVLTALRKLKQLGLIHADLKPENIML 359
>20513
Length = 405
Score = 28.5 bits (62), Expect = 2.4, Method: Compositional matrix adjust.
Identities = 10/26 (38%), Positives = 18/26 (69%)
Frame = -1
Query: 163 DFLDKLLRYDHQSRLTAREAMEHPYF 188
DFL +L +D + R TA ++++HP+
Sbjct: 282 DFLAPMLEFDPEQRATAAQSLQHPWL 205
>18663
Length = 600
Score = 28.5 bits (62), Expect = 2.5, Method: Compositional matrix adjust.
Identities = 13/34 (38%), Positives = 21/34 (61%)
Frame = +2
Query: 63 GPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPF 96
PE+L + Y +S+D W+LG +L M+ + PF
Sbjct: 32 APEILRG-EDYGFSVDWWALGVLLYEMLAGRSPF 130
>28419
Length = 687
Score = 28.5 bits (62), Expect = 2.8, Method: Compositional matrix adjust.
Identities = 26/96 (27%), Positives = 43/96 (44%), Gaps = 5/96 (5%)
Frame = +3
Query: 4 ILKALDYCHSMG----IMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASR 59
ILK L YC ++ ++ K N+ EH K++ + G + +R S+
Sbjct: 342 ILKRLRYCLNLSKPPSYLNTVRKL*NISYVREHDKVKALMLGFKLLVNSQCANALRHPSQ 521
Query: 60 YFKGPELL-VDYQMYDYSLDMWSLGCMLASMIFRKE 94
KGPEL+ D+Q Y++ C+ + RKE
Sbjct: 522 I*KGPELIPYDFQFYEF-----PTACVTSPY*VRKE 614
>20773
Length = 391
Score = 28.1 bits (61), Expect = 3.2, Method: Compositional matrix adjust.
Identities = 16/50 (32%), Positives = 25/50 (50%)
Frame = -1
Query: 138 GRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPY 187
G H R+ F H+ +V+ + + +LL YD RLT A+ HP+
Sbjct: 370 GLHRRRSRPVFPHTT---VVTQHFYNLVQRLLTYDPSQRLTPDLALSHPF 230
>32359
Length = 928
Score = 28.1 bits (61), Expect = 3.2, Method: Compositional matrix adjust.
Identities = 9/17 (52%), Positives = 14/17 (82%)
Frame = -3
Query: 15 GIMHRDVKPHNVMIDHE 31
G+ HRD+KP N+++D E
Sbjct: 65 GVCHRDIKPQNLLLDPE 15
>20152
Length = 445
Score = 28.1 bits (61), Expect = 4.0, Method: Compositional matrix adjust.
Identities = 12/39 (30%), Positives = 23/39 (58%)
Frame = +1
Query: 64 PELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDN 102
PE+L+ ++D+WSLG +L ++ + PF +D+
Sbjct: 1 PEILLGDSYDAPAVDVWSLGVILYMLVVGEAPFQEANDS 117
>01106
Length = 878
Score = 27.7 bits (60), Expect = 4.3, Method: Compositional matrix adjust.
Identities = 11/29 (37%), Positives = 20/29 (68%), Gaps = 1/29 (3%)
Frame = +3
Query: 1 MYEILKALDYCHSMG-IMHRDVKPHNVMI 28
+ ++L+ L Y H+ I+H D+KP N++I
Sbjct: 663 IRQVLEGLSYMHAKCRIIHTDIKPENILI 749
>21210
Length = 518
Score = 27.7 bits (60), Expect = 4.4, Method: Compositional matrix adjust.
Identities = 17/78 (21%), Positives = 36/78 (46%), Gaps = 12/78 (15%)
Frame = +3
Query: 73 YDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLG---------TEDLYDYID 123
YD D+WSLG L + + P+ +DQL ++ + + + D ++++
Sbjct: 63 YDVRSDVWSLGITLMELATGRFPYRKWVSIFDQLQQVVRGVAPCLPHDGAFSHDFVNFVN 242
Query: 124 KY---NIELDPRFNDILG 138
K + + P++N +L
Sbjct: 243 KCLTKDEKQRPKYNKLLA 296
>37603
Length = 1005
Score = 27.3 bits (59), Expect = 6.7, Method: Compositional matrix adjust.
Identities = 10/25 (40%), Positives = 14/25 (56%)
Frame = +2
Query: 2 YEILKALDYCHSMGIMHRDVKPHNV 26
Y + L +CH GI RD +PH +
Sbjct: 551 YHVRIQLSFCHVEGIKRRDGRPHAI 625
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000383076 | hsapiens_gene_ensembl | Casein kinase
II subunit alpha (EC 2.7.11.1) (CK II).
[Source:Uniprot/SWISSPROT;Acc:P68400]
(255 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
03508 194 4e-50
01060 102 2e-22
14126 99 2e-21
04591 89 2e-18
01707 87 5e-18
04138 87 8e-18
32000 85 3e-17
29581 80 1e-15
01756 71 3e-13
15910 69 2e-12
23319 69 3e-12
21079 67 7e-12
12721 62 3e-10
28638 60 9e-10
01392 59 2e-09
26560 59 2e-09
14420 58 5e-09
01966 57 7e-09
03294 55 2e-08
26711 55 3e-08
12786 55 3e-08
13212 55 3e-08
30755 54 4e-08
18287 54 5e-08
19761 54 6e-08
00300 52 2e-07
18921 52 3e-07
18484 51 4e-07
09606 50 7e-07
13592 50 7e-07
18401 50 8e-07
00638 50 1e-06
19094 49 1e-06
31885 49 2e-06
13078 48 3e-06
21433 47 8e-06
13066 45 3e-05
27405 45 4e-05
04852 44 4e-05
03240 43 1e-04
11185 42 2e-04
00715 42 3e-04
17975 41 6e-04
05084 39 0.003
14116 38 0.003
01718 38 0.003
26009 38 0.004
00392 38 0.004
31489 36 0.014
37602 35 0.031
02638 35 0.033
18481 35 0.036
27546 34 0.046
06358 34 0.068
29590 33 0.088
15931 33 0.10
11801 33 0.13
26909 33 0.14
14104 32 0.29
28157 32 0.31
12672 31 0.43
21800 31 0.60
27274 30 0.65
35032 30 0.92
37063 30 1.0
17932 30 1.0
16350 29 1.4
19301 29 1.6
29360 29 1.9
20513 28 2.4
18663 28 2.5
28419 28 2.8
20773 28 3.2
32359 28 3.2
20152 28 4.0
01106 28 4.3
21210 28 4.4
37603 27 6.7
>03508
Length = 1463
Score = 194 bits (492), Expect = 4e-50, Method: Compositional matrix adjust.
Identities = 86/97 (88%), Positives = 93/97 (95%)
Frame = +1
Query: 1 MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRY 60
+YE++KALD+CHSMGIMHRDVKPHNVMIDHE++KLRLIDWGLAEFYHPG EYNVRVASRY
Sbjct: 889 LYELMKALDFCHSMGIMHRDVKPHNVMIDHENKKLRLIDWGLAEFYHPGMEYNVRVASRY 1068
Query: 61 FKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFF 97
FKGPELL+DYQMYDYSLDMWSLGCM ASMIFRKEP
Sbjct: 1069FKGPELLLDYQMYDYSLDMWSLGCMFASMIFRKEPLL 1179
Score = 185 bits (470), Expect = 1e-47, Method: Compositional matrix adjust.
Identities = 89/115 (77%), Positives = 97/115 (84%), Gaps = 3/115 (2%)
Frame = +2
Query: 80 WSLGCMLASM---IFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDI 136
W+ G A + K PFFHGHDNYDQLVRIAKVLGT+DLY YI+KY I+LDPRFNDI
Sbjct: 1118 WTCGVWAACLPA*SSGKSPFFHGHDNYDQLVRIAKVLGTDDLYGYIEKYQIDLDPRFNDI 1297
Query: 137 LGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTV 191
LGRHSRKRWERFVHSENQHL+SPEALDFLDKLLRYDH RLTAREAM+HPYF +
Sbjct: 1298 LGRHSRKRWERFVHSENQHLISPEALDFLDKLLRYDHNERLTAREAMDHPYFXPI 1462
>01060
Length = 1800
Score = 102 bits (253), Expect = 2e-22, Method: Compositional matrix adjust.
Identities = 54/192 (28%), Positives = 103/192 (53%), Gaps = 1/192 (0%)
Frame = +1
Query: 1 MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAE-FYHPGQEYNVRVASR 59
+++I+ + +CH I+HRD+KP N++I+H +++ D+G+A F P + Y V +
Sbjct: 394 VFQIVTGIXFCHQRRIVHRDLKPQNLLINHTG-AIKIADFGMARTFALPVRAYTHEVVTL 570
Query: 60 YFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLY 119
+++ PE+L+ Y +D+WS+G + A M+ R P F G DQL +I +++GT
Sbjct: 571 WYRAPEILMGASKYSTPVDVWSIGTIFADMLIRT-PIFKGDSEIDQLFKIFRIIGTPTEQ 747
Query: 120 DYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTA 179
+ + + + P FN + W+ SE + LD +++ L+ D R++
Sbjct: 748 TWPEFHKL---PAFNGMF-----PLWKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISC 903
Query: 180 REAMEHPYFYTV 191
++ ++H YF V
Sbjct: 904 KKMLQHAYFLNV 939
>14126
Length = 1265
Score = 98.6 bits (244), Expect = 2e-21, Method: Compositional matrix adjust.
Identities = 58/191 (30%), Positives = 100/191 (52%), Gaps = 3/191 (1%)
Frame = +3
Query: 1 MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRY 60
M ++L +D+ HS I+HRD+KP N++I + R L+L D+GLA Y V + +
Sbjct: 534 MLQLLNGVDFLHSNRIVHRDLKPQNLLISKDGR-LKLADFGLARIYSFHMALTTVVVTLW 710
Query: 61 FKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYD 120
++ PE+L+ + Y S+D+WS GC+ A + F + F G +DQL +I +V+G D
Sbjct: 711 YRSPEVLMQAE-YGTSVDIWSCGCIFAEL-FTRRALFKGSSEFDQLKKIFEVIGLPPAGD 884
Query: 121 YIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLV---SPEALDFLDKLLRYDHQSRL 177
+ + ++ R + Q LV P+A D ++K+L + R+
Sbjct: 885 WPEGVSVH-------------RNSFRPTPPVPLQTLVPEMDPQAKDLMEKMLVFKSGRRI 1025
Query: 178 TAREAMEHPYF 188
++RE++ HPY
Sbjct: 1026SSRESLLHPYL 1058
>04591
Length = 1117
Score = 88.6 bits (218), Expect = 2e-18, Method: Compositional matrix adjust.
Identities = 55/190 (28%), Positives = 95/190 (50%)
Frame = -2
Query: 1 MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRY 60
M ++L L Y H+ I+HRD+K N+++ + L+L D+GL+ + + RV + +
Sbjct: 879 MSQLLNGLFYIHTKQILHRDIKAANILLTRDG-VLKLADFGLSRPWVKSKRLTNRVVTLW 703
Query: 61 FKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYD 120
++ PELL+ + Y +DMW +GC++A M RK P G QL I + G+ +
Sbjct: 702 YRPPELLLGEREYGPEIDMWGVGCIMAEMWSRK-PLMQGRSEQHQLSLITDLCGSLNAEV 526
Query: 121 YIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAR 180
+ +EL + + G+ RK ER + L + E + +D LR D R+
Sbjct: 525 WPGVTKLELYGKLDLPQGK-PRKVKERML----DLLKNKEGAELIDIFLRLDPGQRMNCD 361
Query: 181 EAMEHPYFYT 190
A+ H +F+
Sbjct: 360 NALSHDFFWV 331
>01707
Length = 757
Score = 87.4 bits (215), Expect = 5e-18, Method: Compositional matrix adjust.
Identities = 43/115 (37%), Positives = 70/115 (60%), Gaps = 1/115 (0%)
Frame = +1
Query: 1 MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYH-PGQEYNVRVASR 59
+Y+ L A+++CH +HRDVKP N++I + +++L D+G A PG EY VA+R
Sbjct: 379 IYQTLLAVNFCHQYNTIHRDVKPENILITRQG-QVKLCDFGFARILTGPGDEYTDYVATR 555
Query: 60 YFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLG 114
+++ PELLV Y +D+W++GC+ A ++ + + G + DQL I K LG
Sbjct: 556 WYRAPELLVGDTQYGPPVDVWAIGCVFAELL-TGQALWPGRSDVDQLHLIRKTLG 717
>04138
Length = 800
Score = 86.7 bits (213), Expect = 8e-18, Method: Compositional matrix adjust.
Identities = 56/195 (28%), Positives = 101/195 (51%), Gaps = 6/195 (3%)
Frame = +1
Query: 8 LDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPG----QEYNVRVASRYFKG 63
L Y H I+HRD+K N++I + L+L D+GLA + Y RV + +++
Sbjct: 52 LYYIHRNKILHRDMKAANILITKQG-VLKLADFGLARAFSVNLRQPNRYTNRVVTLWYRP 228
Query: 64 PELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLG--TEDLYDY 121
PELL+ + Y ++D W GC++A M + + P G +QL I ++ G T +++
Sbjct: 229 PELLLGDRNYSTAIDQWGAGCIMAEM-WTRNPIMQGTTEQNQLTLITQLCGSITPEVWPG 405
Query: 122 IDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTARE 181
+ + ++ + GR + R +RF + L P LD ++LL+ D R++A E
Sbjct: 406 VTQLSMYHQIKGALAAGRKNIIR-DRFA----RILKDPYGLDLFERLLKMDPSQRISADE 570
Query: 182 AMEHPYFYTVVKDQA 196
A+ H +F+ V+ ++
Sbjct: 571 ALNHDFFWVGVEPKS 615
>32000
Length = 644
Score = 85.1 bits (209), Expect = 3e-17, Method: Compositional matrix adjust.
Identities = 52/158 (32%), Positives = 81/158 (51%), Gaps = 3/158 (1%)
Frame = -1
Query: 34 KLRLIDWGLAE-FYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFR 92
K+++ D+GLA F P + Y V + +++ PE+L+ + Y +D+WSLGC+ M+ R
Sbjct: 575 KMKIADFGLARVFGLPVRTYTHEVITLWYRAPEILLGCRFYSVPVDIWSLGCIFVEMMTR 396
Query: 93 KEPFFHGHDNYDQLVRIAKVLGT--EDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVH 150
+ F G DQL RI + LGT E ++ + K P + + K E V
Sbjct: 395 RA-LFPGDSEIDQLYRIFRTLGTPDEKVWPGVSKL-----PDYKPTFPKWPLKNLETVVS 234
Query: 151 SENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYF 188
+S LD L ++L Y+ R++AR AM HPYF
Sbjct: 233 ------LSKVGLDLLKRMLTYNPNRRISARSAMRHPYF 138
>29581
Length = 1278
Score = 79.7 bits (195), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 54/197 (27%), Positives = 100/197 (50%), Gaps = 9/197 (4%)
Frame = -2
Query: 1 MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFY-HPGQEYNVRVASR 59
+ ++LK L Y H I+HRD+K N+++ + +++ D+GLA Y P + +V +
Sbjct: 1031 VLQLLKGLRYLHEAFIIHRDLKVSNLLMT-DKGCVKIADFGLARNYGKPQKPMTPKVVTL 855
Query: 60 YFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLY 119
+++ PELL + + ++DMWS GC+L ++ K P G + Q+ I ++LGT +
Sbjct: 854 WYRAPELLFGSKTHSTAIDMWSAGCILGELLGHK-PLMPGRSDLQQIELIMELLGTPNDT 678
Query: 120 DY--------IDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRY 171
+ +++ ++ P +N++ RH+ W +S + L+ L Y
Sbjct: 677 IWPGFSQLPAFEQFTLKKQP-YNNL--RHTFP-W-----------LSESGIRLLNGLFMY 543
Query: 172 DHQSRLTAREAMEHPYF 188
Q R TA + +EH YF
Sbjct: 542 HPQKRATAEDCLEHSYF 492
>01756
Length = 1858
Score = 71.2 bits (173), Expect = 3e-13, Method: Compositional matrix adjust.
Identities = 37/119 (31%), Positives = 64/119 (53%), Gaps = 4/119 (3%)
Frame = -3
Query: 1 MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPG----QEYNVRV 56
M +++ L Y H I+HRD+K N++I + L+L D+GLA + Y RV
Sbjct: 1403 MKQLMNGLYYIHRNKILHRDMKAANILITKQG-VLKLADFGLARAFSVNLRQPNRYTNRV 1227
Query: 57 ASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGT 115
+ +++ PELL+ + Y ++D W GC++A M + + P G +QL I ++ G+
Sbjct: 1226 VTLWYRPPELLLGDRNYSTAIDQWGAGCIMAEM-WTRNPIMQGTTEQNQLTLITQLCGS 1053
>15910
Length = 1361
Score = 68.9 bits (167), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 52/191 (27%), Positives = 86/191 (45%), Gaps = 2/191 (1%)
Frame = +2
Query: 3 EILKALDYCHSMGIMHRDVKPHNVMID--HEHRKLRLIDWGLAEFYHPGQEYNVRVASRY 60
+IL + Y H+ G++HRD+KP N++ + + KL+L D+GL+ P + + +
Sbjct: 488 DILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLADFGLSRIIEPEVQMSTVCGTPG 667
Query: 61 FKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYD 120
+ PE+L Y S+DMWS+G + ++ EPFF ++ ++Y
Sbjct: 668 YCAPEVL-KGDKYTPSVDMWSVGVIAYILLCGYEPFFAENEF--------------EMYR 802
Query: 121 YIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAR 180
I K + D + W +S A D + KLL D + RLTA
Sbjct: 803 KIIKGEYKFDEEY-----------WSE---------ISENAKDVVRKLLVIDPKKRLTAT 922
Query: 181 EAMEHPYFYTV 191
EA+ P+ V
Sbjct: 923 EALRLPWVKGV 955
>23319
Length = 2235
Score = 68.6 bits (166), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 42/120 (35%), Positives = 60/120 (50%), Gaps = 2/120 (1%)
Frame = +3
Query: 71 QMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLG--TEDLYDYIDKYNIE 128
+MY S+DMWS GC+ A + P F G+D+ DQL RI K+LG TED + + +
Sbjct: 21 KMYSTSIDMWSAGCIFAELANAGRPLFPGNDDDDQLKRIFKLLGTPTEDQWPGMTQL--- 191
Query: 129 LDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYF 188
P + H W++ V N + D L LL R++A EA++HPYF
Sbjct: 192 --PNYRMFPMYHVTTTWQQVVPKLNS-----KGRDLLQCLLVCCPSDRMSADEALQHPYF 350
>21079
Length = 878
Score = 67.0 bits (162), Expect = 7e-12, Method: Compositional matrix adjust.
Identities = 30/84 (35%), Positives = 50/84 (59%), Gaps = 1/84 (1%)
Frame = +1
Query: 3 EILKALDYCHSMGIMHRDVKPHNVM-IDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYF 61
+I + Y H+ I+H D+KP NV+ + ++++ID+GLA FY PG V + F
Sbjct: 151 QICSGVGYMHTQSILHLDLKPENVLCVSDNSNQIKIIDFGLARFYKPGDSLQVLFGTPEF 330
Query: 62 KGPELLVDYQMYDYSLDMWSLGCM 85
PE +V+Y +++ DMWS+G +
Sbjct: 331 IAPE-VVNYDEINFTTDMWSIGVI 399
>12721
Length = 821
Score = 61.6 bits (148), Expect = 3e-10, Method: Compositional matrix adjust.
Identities = 33/95 (34%), Positives = 57/95 (60%), Gaps = 1/95 (1%)
Frame = +1
Query: 5 LKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGL-AEFYHPGQEYNVRVASRYFKG 63
LKAL + H+ G++HRD+K ++++ H+ K++L D+G A+ Q+ V + Y+
Sbjct: 403 LKALAFLHANGVIHRDIKSDSILLSHDG-KVKLXDFGFCAQVTQDLQKRKSLVGTPYWMA 579
Query: 64 PELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFH 98
PE++ Y +D+WSLG M+ MI + PFF+
Sbjct: 580 PEVISRLP-YGPEVDIWSLGIMVMEMIDAEPPFFN 681
>28638
Length = 1458
Score = 60.1 bits (144), Expect = 9e-10, Method: Compositional matrix adjust.
Identities = 28/77 (36%), Positives = 49/77 (63%), Gaps = 1/77 (1%)
Frame = -1
Query: 14 MGIMHRDVKPHNVMIDHEHRK-LRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQM 72
M I+H D+KP N+++ + R ++++D+G + GQ + SR+++ PE+L+
Sbjct: 774 MNIIHCDLKPENILLCNPKRSAIKIVDFGSS--CQLGQRIYQYIQSRFYRSPEVLLGVP- 604
Query: 73 YDYSLDMWSLGCMLASM 89
YD ++DMWSLGC+L M
Sbjct: 603 YDLAIDMWSLGCILVEM 553
Score = 32.3 bits (72), Expect = 0.18, Method: Compositional matrix adjust.
Identities = 32/142 (22%), Positives = 60/142 (42%), Gaps = 32/142 (22%)
Frame = -2
Query: 79 MWSLGCMLASMIFRK----EPFFHGHDNYDQLVRIAKVLG------------TEDLYDYI 122
W L C ++ + + P F G + +DQ+++I +VLG T +D +
Sbjct: 599 TWPLTCGXWAVYWWRCTXGNPLFAGSNEFDQMMKIVEVLGVPPRHILDQAQKTRKYFDLL 420
Query: 123 -------------DKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLL 169
KY + +++LG R + E H V+ + L F D +L
Sbjct: 419 PDGTYAPKKPRDNKKYKSPSSRKLHEVLGAEKGGPGGRRM-GEPGHTVA-DYLKFKDLIL 246
Query: 170 R---YDHQSRLTAREAMEHPYF 188
R +D ++R++ A++H +F
Sbjct: 245 RMLDFDPKTRISPYYALQHNFF 180
>01392
Length = 1806
Score = 59.3 bits (142), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 55/199 (27%), Positives = 84/199 (42%), Gaps = 12/199 (6%)
Frame = -1
Query: 4 ILKALDYCHSMGIMHRDVKPHNVMIDH--EHRKLRLIDWGLAEFYH------PGQEYNVR 55
I +ALD+ HS GI HRD+KP N++ +H + +++ D+ LA E
Sbjct: 1764 IARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGISCDGDGTKTPELLTP 1585
Query: 56 VASRYFKGPEL----LVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAK 111
V S + PE+ + D YD D+WSLG +L M+ PF Y Q
Sbjct: 1584 VGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILYIMLCGYPPF------YGQCGEDCG 1423
Query: 112 VLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRY 171
E +D D FN I H + S+ +S A D + LL
Sbjct: 1422 WNRGEACHDCQDML-------FNSIQDGHYK------FPSQEWTSISSSAKDLIRHLLVR 1282
Query: 172 DHQSRLTAREAMEHPYFYT 190
+ + R +A + ++HP+ T
Sbjct: 1281 EPRKRYSAADVLKHPWICT 1225
>26560
Length = 398
Score = 58.9 bits (141), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 32/94 (34%), Positives = 56/94 (59%)
Frame = -1
Query: 3 EILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFK 62
E++ L++ HS +++RD+KP N+++D E+ +R+ D GLA + + + V + +
Sbjct: 332 EVMLGLEHMHSRFVVYRDLKPANILLD-ENGHVRISDLGLACDFSKKRPH-ASVGTHGYM 159
Query: 63 GPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPF 96
PE+L+ Q YD S D +S GCML ++ PF
Sbjct: 158 APEVLMKGQSYDSSADWFSFGCMLYKLLKGHSPF 57
>14420
Length = 528
Score = 57.8 bits (138), Expect = 5e-09, Method: Compositional matrix adjust.
Identities = 30/97 (30%), Positives = 55/97 (56%), Gaps = 1/97 (1%)
Frame = +2
Query: 3 EILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQ-EYNVRVASRYF 61
E L+AL++ H ++HRD+K N+++ + ++L D+G P Q + + V + Y+
Sbjct: 221 ECLQALEFLHENQVIHRDIKSDNILLGMDG-SVKLTDFGFCAQLSPEQSKRSTMVGTPYW 397
Query: 62 KGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFH 98
PE++ Q Y ++D+WSLG M MI + P+ +
Sbjct: 398 MAPEVVTRKQ-YGPTVDIWSLGVMCIEMIEGEPPYLN 505
>01966
Length = 1735
Score = 57.0 bits (136), Expect = 7e-09, Method: Compositional matrix adjust.
Identities = 32/119 (26%), Positives = 58/119 (48%)
Frame = -3
Query: 73 YDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPR 132
Y +D+WS+G + A M+ R P F G DQL +I +++GT + + + + P
Sbjct: 1175 YSTPVDVWSIGTIFADMLIRT-PIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKL---PA 1008
Query: 133 FNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTV 191
FN + W+ SE + LD +++ L+ D R++ ++ ++H YF V
Sbjct: 1007 FNGMF-----PLWKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYFLNV 846
Score = 55.5 bits (132), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 25/86 (29%), Positives = 52/86 (60%), Gaps = 1/86 (1%)
Frame = -1
Query: 1 MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAE-FYHPGQEYNVRVASR 59
+++I+ +++CH I+HRD+KP N++I+H +++ D+G+A F P + Y V +
Sbjct: 1390 VFQIVTGINFCHQRRIVHRDLKPQNLLINHTG-AIKIADFGMARTFALPVRAYTHEVVTL 1214
Query: 60 YFKGPELLVDYQMYDYSLDMWSLGCM 85
+++ PE+L+ Q + W+ G +
Sbjct: 1213 WYRAPEILMGPQ---STPPXWTCGAL 1145
>03294
Length = 1684
Score = 55.5 bits (132), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 31/115 (26%), Positives = 57/115 (49%)
Frame = -1
Query: 77 LDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDI 136
+D+WS+G + A M+ R P F G DQL +I +++GT + + + + P FN +
Sbjct: 1672 VDVWSIGTIFADMLIRT-PIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKL---PAFNGM 1505
Query: 137 LGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTV 191
W+ SE + LD +++ L+ D R++ ++ ++H YF V
Sbjct: 1504 F-----PLWKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYFLNV 1355
>26711
Length = 405
Score = 55.1 bits (131), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 28/95 (29%), Positives = 53/95 (55%), Gaps = 1/95 (1%)
Frame = -2
Query: 3 EILKALDYCHSMGIMHRDVKPHNVMIDHEH-RKLRLIDWGLAEFYHPGQEYNVRVASRYF 61
++L L + H+ G++H D+KP N+++ + ++LID+GLA +P QE + + F
Sbjct: 392 QVLDILQHVHAQGVVHMDLKPSNLLLSGDKLDSVQLIDFGLARKLYPPQETFLNHGTPGF 213
Query: 62 KGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPF 96
PE L D + + D+W +G + ++ + PF
Sbjct: 212 TSPEAL-DVKPISTASDVWGVGVLAYILLSGQSPF 111
>12786
Length = 460
Score = 55.1 bits (131), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 38/130 (29%), Positives = 66/130 (50%), Gaps = 22/130 (16%)
Frame = -3
Query: 3 EILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEY---NVRVASR 59
E+L+A+ H+ G++H D+KP N M+ + L+LID+G+A + + RV +
Sbjct: 386 EMLRAVKALHNEGVIHSDLKPANFMLVAGN--LKLIDFGIANTLQQDKTSVLKDSRVGTP 213
Query: 60 YFKGPELLV-------DYQMYD--------YSL----DMWSLGCMLASMIFRKEPFFHGH 100
+ PE ++ D M + Y + D+WSLGC+L +M++ + PF H
Sbjct: 212 SYMSPEAIMAACDDSADDSMEEDGHRTKPKYKVGVRSDVWSLGCILYNMVYGRTPFQHIK 33
Query: 101 DNYDQLVRIA 110
+N +L I
Sbjct: 32 NNMGKLQAIT 3
>13212
Length = 1067
Score = 54.7 bits (130), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 50/194 (25%), Positives = 82/194 (42%), Gaps = 7/194 (3%)
Frame = -1
Query: 2 YEILKALDYCHSMGIMHRDVKPHNVM--IDHEHRKLRLIDWGL-AEFYHPGQEYNVRVAS 58
+E+ ALD+ H ++HRD+K NV+ ID E ++L D+G+ A+ Q+ + + +
Sbjct: 959 HEMCMALDFLHRHHVIHRDIKAGNVLLTIDGE---VKLADFGVSAKNTQTQQKRDTFIGT 789
Query: 59 RYFKGPELLVDYQM----YDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLG 114
Y+ PE+++ + YD+ D+WSLG L + P H L++I K
Sbjct: 788 PYWMAPEVVLCETLKDTPYDFKADIWSLGVTLIEFAQIEPPNKEMH-PMRVLIKIHK--- 621
Query: 115 TEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQ 174
+D K+W + DF+ K L D
Sbjct: 620 -------------------SDPPTLEKPKKWTKLFK------------DFIAKCLVKDPN 534
Query: 175 SRLTAREAMEHPYF 188
R TA E +EHP+
Sbjct: 533 LRPTAAELLEHPFM 492
>30755
Length = 1137
Score = 54.3 bits (129), Expect = 4e-08, Method: Compositional matrix adjust.
Identities = 35/112 (31%), Positives = 60/112 (53%), Gaps = 2/112 (1%)
Frame = +2
Query: 3 EILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLA-EFYHPGQEYNVRVASRYF 61
EI+ AL Y HS GI++RD+K N+++D + +++ D+GL E G+ + +
Sbjct: 56 EIISALGYLHSQGIIYRDLKLENLLLDKDGH-IKVADFGLCKEDITYGRTTKTFCGTPEY 232
Query: 62 KGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFH-GHDNYDQLVRIAKV 112
PE+L D Y ++D W G ++ MI + PF++ HD L+ + V
Sbjct: 233 LAPEVLDDND-YGRAVDWWGTGVVMYEMICGRLPFYNRDHDVLFTLILVEDV 385
>18287
Length = 678
Score = 54.3 bits (129), Expect = 5e-08, Method: Compositional matrix adjust.
Identities = 35/119 (29%), Positives = 63/119 (52%), Gaps = 3/119 (2%)
Frame = -3
Query: 73 YDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGT---EDLYDYIDKYNIEL 129
YDYS+D+WS+GC+ A ++ R+ F QL I ++GT ED+ +
Sbjct: 673 YDYSIDIWSVGCIFAELLSRRI-LFQAQGPVQQLDMIINLVGTPRPEDMERACEGAR--- 506
Query: 130 DPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYF 188
N IL + R++ +++ + H + EA+ L ++L + ++R++A EA+ HPY
Sbjct: 505 ----NHILNQPFRRQNLLTLYNLSPH-ATHEAVRLLTRMLILNPKNRISAEEALSHPYL 344
>19761
Length = 473
Score = 53.9 bits (128), Expect = 6e-08, Method: Compositional matrix adjust.
Identities = 37/121 (30%), Positives = 60/121 (49%), Gaps = 3/121 (2%)
Frame = -3
Query: 1 MYEILKALDYCHSMG--IMHRDVKPHNVMIDHEHRKLRLIDWGLA-EFYHPGQEYNVRVA 57
+ + AL+Y H+ I+HRD+KP N+ + E +RL D GLA + P +V
Sbjct: 405 LMQTASALNYMHTHTPVILHRDLKPQNIYVT-EKGDVRLGDLGLARKLTGPADFATSQVG 229
Query: 58 SRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTED 117
+ + PE+L Q Y+ D+WSLGC+ + +K G D + + +V+G
Sbjct: 228 TIMYLSPEIL-SQQPYNSKSDIWSLGCVFYDITGKK-----GSDEMGVMFLLVQVMGGRK 67
Query: 118 L 118
L
Sbjct: 66 L 64
>00300
Length = 2318
Score = 52.4 bits (124), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 32/115 (27%), Positives = 60/115 (52%), Gaps = 7/115 (6%)
Frame = -1
Query: 3 EILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLA-----EFYHPGQEYNVRVA 57
EI+ A+++ H I+HRD+K N+ + + ++L D+G + PG+ +N+ V
Sbjct: 1343 EIVLAVNHLHENSIVHRDIKGANIFLT-SNGHVKLGDFGCSVKLKSHTTMPGEFHNL-VG 1170
Query: 58 SRYFKGPELLV--DYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIA 110
+ + PE+ D Y + D+WSLGC++ M K P+ +NY + ++
Sbjct: 1169 TTAYMAPEVFTQNDQGGYGRAADIWSLGCVVIEMATGKRPWHDLDNNYQIMYKVG 1005
>18921
Length = 697
Score = 51.6 bits (122), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 31/99 (31%), Positives = 51/99 (51%), Gaps = 1/99 (1%)
Frame = +2
Query: 1 MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLA-EFYHPGQEYNVRVASR 59
+Y LK L Y HS +HRD+K N+++++E +L D+G+A + + N + +
Sbjct: 335 LYYTLKGLXYLHSRRKIHRDIKAGNILLNNEGHA-KLADFGVAGQLTDTMAKRNTVIGTP 511
Query: 60 YFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFH 98
Y+ PE++ + YD D+WSLG M K P
Sbjct: 512 YWMAPEVIQEIG-YDCVADIWSLGITALEMAEGKPPVME 625
>18484
Length = 635
Score = 51.2 bits (121), Expect = 4e-07, Method: Compositional matrix adjust.
Identities = 33/100 (33%), Positives = 53/100 (53%), Gaps = 6/100 (6%)
Frame = +1
Query: 3 EILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFK 62
EI L + H GI++RD+K NVM+D E +++ D+G+ + G +R F
Sbjct: 67 EIAVGLFFLHDQGIIYRDLKLDNVMLDSEGH-IKIADFGMCKEGMTGD-----ATTRTFC 228
Query: 63 G------PELLVDYQMYDYSLDMWSLGCMLASMIFRKEPF 96
G PE+++ YQ Y S+D W+ G +L M+ + PF
Sbjct: 229 GTPDYIAPEIVL-YQPYSKSVDWWAYGVLLFEMLAGQPPF 345
>09606
Length = 1300
Score = 50.4 bits (119), Expect = 7e-07, Method: Compositional matrix adjust.
Identities = 51/210 (24%), Positives = 86/210 (40%), Gaps = 25/210 (11%)
Frame = -3
Query: 4 ILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAE------------FYHPGQE 51
++ L Y HS+GI+ D++P V++D L+ D+GL++ F G +
Sbjct: 806 LVTGLHYIHSLGILFHDLRPSKVLLD-TSGVLKFADFGLSKVEGENLEELFFKFAEAGDQ 630
Query: 52 YNVRVASRYFK-----------GPELLVDYQMYDYSL--DMWSLGCMLASMIFRKEPFFH 98
+N++ A K PE+ +Q + S+ D+W+LGC+ M F P F
Sbjct: 629 WNIQSAEEMMKQVPTSGSPTYMAPEV---FQGAEPSIMSDLWALGCVFYEM-FSGHPPFL 462
Query: 99 GHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVS 158
G + YD + KVL E + + P S
Sbjct: 461 G-ETYD--ITKDKVLNKEFPLPKVKGSRLSAKP--------------------------S 369
Query: 159 PEALDFLDKLLRYDHQSRLTAREAMEHPYF 188
PE L+ L+ LL+ D RL+ ++H ++
Sbjct: 368 PEFLNLLESLLQKDSTRRLSWASLVKHAFW 279
>13592
Length = 980
Score = 50.4 bits (119), Expect = 7e-07, Method: Compositional matrix adjust.
Identities = 44/192 (22%), Positives = 78/192 (40%), Gaps = 7/192 (3%)
Frame = +2
Query: 3 EILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYH-----PGQEYNVRVA 57
++L + H GI+HRD+K N+ + L+L D+G A PG E V
Sbjct: 305 QLLSGVAELHKHGIVHRDIKTANIFLVDGSNSLKLGDFGSAVKIQAHTTVPG-ELQGYVG 481
Query: 58 SRYFKGPELLVDYQMYDYS--LDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGT 115
++ + PE+ + D+WS+GC++ M K P+ N+ + ++ +G
Sbjct: 482 TQAYMAPEVFTKTNSDGHGRLADIWSVGCVVVEMASGKRPWAQFDSNFQIMFKVG--MGE 655
Query: 116 EDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQS 175
+ P+ + L S E DF+D L++D +
Sbjct: 656 K--------------PQAPESL--------------------SQEGHDFIDHCLQHDPKQ 733
Query: 176 RLTAREAMEHPY 187
RL+A E +E +
Sbjct: 734 RLSAIELLEQNF 769
>18401
Length = 463
Score = 50.4 bits (119), Expect = 8e-07, Method: Compositional matrix adjust.
Identities = 35/143 (24%), Positives = 74/143 (51%), Gaps = 10/143 (6%)
Frame = -3
Query: 56 VASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGT 115
V++R+++ PE++++ + + D+WS+GC++ ++ F HDN + L + ++LG+
Sbjct: 449 VSTRHYRAPEVILELG-WSHPCDVWSVGCIMFE-LYTGYTLFQTHDNKEHLAMMERILGS 276
Query: 116 EDLYDYIDKYNIE-------LDPRFNDILGRHSRKRWE---RFVHSENQHLVSPEALDFL 165
Y K + LD + R+ R+ + R+V + ++ + D +
Sbjct: 275 LP-YRMAKKTKKQKYFHHGRLDVPERSSMARYVRENTKPLLRYV-KDRENKDHQQLFDLM 102
Query: 166 DKLLRYDHQSRLTAREAMEHPYF 188
KLL Y+ SR + +A++HP+F
Sbjct: 101 KKLLAYEASSRYSLLQALQHPFF 33
>00638
Length = 1595
Score = 49.7 bits (117), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 19/23 (82%), Positives = 23/23 (100%)
Frame = +2
Query: 1 MYEILKALDYCHSMGIMHRDVKP 23
+YE++KALD+CHSMGIMHRDVKP
Sbjct: 434 LYELMKALDFCHSMGIMHRDVKP 502
>19094
Length = 898
Score = 49.3 bits (116), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 29/90 (32%), Positives = 49/90 (54%), Gaps = 1/90 (1%)
Frame = +1
Query: 1 MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLA-EFYHPGQEYNVRVASR 59
+Y LK L Y HS +HRD+K N+++++E +L D+G+A + + N + +
Sbjct: 76 LYYTLKGL*YLHSRRKIHRDIKAGNILLNNEGHA-KLADFGVAGQLTDTMAKRNTVIGTP 252
Query: 60 YFKGPELLVDYQMYDYSLDMWSLGCMLASM 89
Y+ PE++ + YD D+WSLG M
Sbjct: 253 YWMAPEVIQEIG-YDCVADIWSLGITALEM 339
>31885
Length = 529
Score = 48.9 bits (115), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 27/100 (27%), Positives = 51/100 (51%), Gaps = 4/100 (4%)
Frame = -2
Query: 1 MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRY 60
+ ++ LDY S I+HRD+KP N+++D E + D+ +A + +R
Sbjct: 354 LCQLALVLDYLRSQKIVHRDIKPDNILLD-EQGHCHVTDFNIATQLEDDELATSTSGTRP 178
Query: 61 FKGPEL----LVDYQMYDYSLDMWSLGCMLASMIFRKEPF 96
+ PE+ + + + Y + +D WSLG L ++ ++ PF
Sbjct: 177 YMAPEVYGVAINERRGYGFPVDWWSLGVSLFELLKKRRPF 58
>13078
Length = 773
Score = 48.1 bits (113), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 37/126 (29%), Positives = 61/126 (48%), Gaps = 14/126 (11%)
Frame = -1
Query: 77 LDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDK-------YNIEL 129
D+WS+GC++ ++ F HDN + L + ++LG+ Y K Y+ L
Sbjct: 734 CDVWSIGCIMFE-LYTGYTLFQTHDNKEHLAMMERILGSLP-YRMAKKTKKQKYFYHGRL 561
Query: 130 DPRFNDILGRHSR---KRWERFV----HSENQHLVSPEALDFLDKLLRYDHQSRLTAREA 182
D GR+ R K R+V + ++Q L D +DK+L Y+ +R + R+A
Sbjct: 560 DWDEKSSAGRYVRDNVKPLRRYVKDPDNEDHQQL-----FDLMDKMLSYEVSTRYSLRQA 396
Query: 183 MEHPYF 188
M HP+F
Sbjct: 395 MRHPFF 378
>21433
Length = 590
Score = 47.0 bits (110), Expect = 8e-06, Method: Compositional matrix adjust.
Identities = 42/171 (24%), Positives = 75/171 (43%)
Frame = +2
Query: 1 MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRY 60
+Y++ AL+YCH ++HRD+KP N+++ L++ D+G + + P +
Sbjct: 185 IYQLSSALEYCHYRKVIHRDIKPENLLLG-LKGDLKIADFGWS-VHAPSSRRTTMCGTLD 358
Query: 61 FKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYD 120
+ PE +V+ + +D ++D+WSLG + Y+ LV GT L
Sbjct: 359 YLPPE-MVEGKTHDENVDLWSLGVLC----------------YEFLV------GTPPLRP 469
Query: 121 YIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRY 171
+ PR+ S + +V+P A D + KLLR+
Sbjct: 470 SPTRPPTPASPRWT----------------SGSPSIVTPGARDLISKLLRH 574
>13066
Length = 551
Score = 44.7 bits (104), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 27/87 (31%), Positives = 43/87 (49%), Gaps = 4/87 (4%)
Frame = +3
Query: 1 MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGL--AEFYHPGQEYNVR--V 56
Y++ AL+Y HS + HRD+K N+++ H ++L D+G A G++Y R
Sbjct: 294 FYQMTTALNYLHSYDVAHRDLKCENILLS-SHFNVKLADFGFACACITESGEKYMSRTYC 470
Query: 57 ASRYFKGPELLVDYQMYDYSLDMWSLG 83
S + PE++ D WSLG
Sbjct: 471 GSAAYAAPEIVYGAPYAPKVADAWSLG 551
>27405
Length = 532
Score = 44.7 bits (104), Expect = 4e-05, Method: Compositional matrix adjust.
Identities = 25/76 (32%), Positives = 47/76 (61%)
Frame = -3
Query: 3 EILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFK 62
E++ L++ HS +++RD+KP N+++D E+ +R+ D GLA + ++ + V + +
Sbjct: 230 EVMLGLEHMHSRFVVYRDLKPANILLD-ENGHVRISDLGLACDFSK-KKPHASVGTHGYM 57
Query: 63 GPELLVDYQMYDYSLD 78
PE+L+ Q YD S D
Sbjct: 56 APEVLMKGQAYDSSAD 9
>04852
Length = 1462
Score = 44.3 bits (103), Expect = 4e-05, Method: Compositional matrix adjust.
Identities = 27/88 (30%), Positives = 45/88 (51%), Gaps = 3/88 (3%)
Frame = +1
Query: 2 YEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRY- 60
++I + +++ S +HRD+ NV++ EH L++ D+GL+ G Y R R
Sbjct: 346 FQIARGMEFLASRKCIHRDLAARNVLVTEEH-VLKIADFGLS---RTGDYYKKRSGGRLP 513
Query: 61 --FKGPELLVDYQMYDYSLDMWSLGCML 86
+ PE L D + Y D+WS G +L
Sbjct: 514 VKWMAPEALFDMR-YTTKSDVWSFGVVL 594
>03240
Length = 1683
Score = 43.1 bits (100), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 33/140 (23%), Positives = 53/140 (37%), Gaps = 45/140 (32%)
Frame = -3
Query: 3 EILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGL-------------------- 42
E+++A++ H MG +HRD+KP N++ID ++L D+GL
Sbjct: 967 ELVQAIESVHRMGFIHRDIKPDNILIDRNGH-IKLTDFGLCTGFRWTHNSKYYQRDGTHA 791
Query: 43 ----------------AEFYHPGQEYNVR---------VASRYFKGPELLVDYQMYDYSL 77
E P + R V + + PE+L Y
Sbjct: 790 RQDSMEVKCQLDEQCQCEILKPLERRRKREQRCLAHSLVGTPNYIAPEVLSRLGGYTSVC 611
Query: 78 DMWSLGCMLASMIFRKEPFF 97
D WS+G +L M+ PF+
Sbjct: 610 DWWSVGVILFEMLVGHPPFY 551
>11185
Length = 473
Score = 42.4 bits (98), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 29/112 (25%), Positives = 52/112 (46%), Gaps = 25/112 (22%)
Frame = +1
Query: 4 ILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAE------------FYHPGQE 51
++ L Y HS+GI+ D++P V++D L+ D+GL++ F G +
Sbjct: 28 LVTGLHYIHSLGILFHDLRPSKVLLDTSGV-LKFADFGLSKVEGENLEELFFKFAEAGDQ 204
Query: 52 YNVRVASRYFK-----------GPELLVDYQMYDYSL--DMWSLGCMLASMI 90
+N++ A K PE+ +Q + S+ D+W+LGC+ M
Sbjct: 205 WNIQSAEEMMKQVPTSGSPTYMAPEV---FQGAEPSIMSDLWALGCVFYEMF 351
>00715
Length = 1788
Score = 41.6 bits (96), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 32/117 (27%), Positives = 50/117 (42%), Gaps = 23/117 (19%)
Frame = +1
Query: 3 EILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHP-------------- 48
++ + L Y HS+ I+H D+KP N ++ + KLR+ D+G P
Sbjct: 262 QMARGLHYLHSINIVHLDLKPANCLLTRD-LKLRIADFGCCHQLTPTGLDMGEREGGMAG 438
Query: 49 ---------GQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPF 96
G N + ++ PELL Q S D++SLG L M R+ P+
Sbjct: 439 NELELTPVQGAWKNELAGTLAYRAPELLKGLQPSVRS-DVYSLGITLWQMCTRQGPY 606
>17975
Length = 449
Score = 40.8 bits (94), Expect = 6e-04, Method: Compositional matrix adjust.
Identities = 15/41 (36%), Positives = 29/41 (70%)
Frame = +3
Query: 3 EILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLA 43
+I++A+ YCH + ++HRD+KP NV+ + ++L D+G +
Sbjct: 291 QIVEAISYCHKLHVVHRDLKPENVVFFEKPGLVKLTDFGFS 413
>05084
Length = 1324
Score = 38.5 bits (88), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 25/91 (27%), Positives = 39/91 (42%), Gaps = 1/91 (1%)
Frame = +2
Query: 99 GHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDI-LGRHSRKRWERFVHSENQHLV 157
G DQLV I KVLGT + E++P +++ + W +
Sbjct: 8 GDSGVDQLVEIIKVLGTPT-----REQIREMNPNYSEFKFPQIKAHPWTKVFRPRT---- 160
Query: 158 SPEALDFLDKLLRYDHQSRLTAREAMEHPYF 188
PEA+ + +LL Y +R+ EA H +F
Sbjct: 161 PPEAIQLVSRLLEYTPSARIQPMEACAHAFF 253
>14116
Length = 1017
Score = 38.1 bits (87), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 24/95 (25%), Positives = 47/95 (49%), Gaps = 5/95 (5%)
Frame = -1
Query: 3 EILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLA-----EFYHPGQEYNVRVA 57
+I + +DY + +HRD+ N M+D E +++ D+GLA + Y+ + ++
Sbjct: 297 DIARGMDYLAGLKFVHRDLAARNCMLD-EDFHVKVADFGLARDIYEKEYYSSENKKAKLP 121
Query: 58 SRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFR 92
++ L + YD D+WS G +L ++ R
Sbjct: 120 VKWMALESL--EKGNYDSKTDVWSYGVVLWELLTR 22
>01718
Length = 959
Score = 38.1 bits (87), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 28/92 (30%), Positives = 47/92 (51%), Gaps = 5/92 (5%)
Frame = +3
Query: 6 KALDYCHSMGIMHRDVKPHNVMIDHEHR---KLRLIDWGLA-EFYHP-GQEYNVRVASRY 60
+ LDY HS +HRD+ N++I E + D+GLA + P +E V S Y
Sbjct: 468 RGLDYLHSTRFIHRDLTSKNILIRREDNHGYHAVIADFGLATKIPDPLDKEKLPTVGSPY 647
Query: 61 FKGPELLVDYQMYDYSLDMWSLGCMLASMIFR 92
+ PE+L + Y+ D++S+G ++ + R
Sbjct: 648 WMAPEVL-NGHFYNERADLFSVGIIMCEITAR 740
>26009
Length = 886
Score = 38.1 bits (87), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 14/28 (50%), Positives = 22/28 (78%)
Frame = +3
Query: 1 MYEILKALDYCHSMGIMHRDVKPHNVMI 28
M +++ ALD+ HS ++HRD+KP NV+I
Sbjct: 729 MKQLVSALDFMHSKQLVHRDIKPENVLI 812
>00392
Length = 668
Score = 37.7 bits (86), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 25/87 (28%), Positives = 48/87 (55%), Gaps = 3/87 (3%)
Frame = +3
Query: 3 EILKALDYCHSMG--IMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRY 60
++LK L + H+ ++HRD+K N+ I +++ D GLA + +V + +
Sbjct: 270 QVLKGLYFLHTRTPPVIHRDLKCDNIFITGPTGSVKIGDLGLATLKNQSFAKSV-IGTPE 446
Query: 61 FKGPELLVDYQMYDYSLDMWSLG-CML 86
F PE+ ++ YD ++D+++ G CML
Sbjct: 447 FMAPEMYEEH--YDEAVDVYAFGMCML 521
>31489
Length = 329
Score = 36.2 bits (82), Expect = 0.014, Method: Compositional matrix adjust.
Identities = 13/27 (48%), Positives = 21/27 (77%)
Frame = +3
Query: 1 MYEILKALDYCHSMGIMHRDVKPHNVM 27
+Y+IL+ L Y HS ++HRD+KP N++
Sbjct: 183 LYQILRGLKYIHSANVVHRDLKPSNLL 263
>37602
Length = 804
Score = 35.0 bits (79), Expect = 0.031, Method: Compositional matrix adjust.
Identities = 20/59 (33%), Positives = 29/59 (49%)
Frame = -1
Query: 3 EILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYF 61
E LK L Y H G MHRD+K N+++ E D LA+F+ ++ V + F
Sbjct: 195 ETLKGLHYLHRRGKMHRDIKGANILLTEEG------DVKLADFWRVSSNHSHNVQKKVF 37
>02638
Length = 1490
Score = 35.0 bits (79), Expect = 0.033, Method: Compositional matrix adjust.
Identities = 31/128 (24%), Positives = 52/128 (40%)
Frame = +1
Query: 61 FKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYD 120
F PE+L + Y + D+WS+GC++ M + P ++ HD + L I K+ +
Sbjct: 34 FMAPEVL-RGESYGRACDVWSVGCVMIEMCTCRPP-WNSHDISNHLALIFKIASS----- 192
Query: 121 YIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAR 180
+D I EN +SP D + + L D R +A+
Sbjct: 193 -VDPPPI-----------------------PEN---MSPPVRDLMLRCLEQDSDFRPSAK 291
Query: 181 EAMEHPYF 188
+ + HP F
Sbjct: 292 DLLMHPLF 315
>18481
Length = 437
Score = 34.7 bits (78), Expect = 0.036, Method: Compositional matrix adjust.
Identities = 19/51 (37%), Positives = 31/51 (60%), Gaps = 3/51 (5%)
Frame = -1
Query: 3 EILKALDYCHSMGIMHRDVKPHNVMID---HEHRKLRLIDWGLAEFYHPGQ 50
++L L++ H +HRD+KP N ++ H HR L +ID+GL++ Y Q
Sbjct: 173 QLLSRLEFIHQKCFIHRDLKPDNFLMGLGRHCHR-LYIIDFGLSKRYKDTQ 24
>27546
Length = 426
Score = 34.3 bits (77), Expect = 0.046, Method: Compositional matrix adjust.
Identities = 15/45 (33%), Positives = 28/45 (62%)
Frame = -1
Query: 1 MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEF 45
+++ KAL Y HS I HRD+K N+++ + +++ D+G A +
Sbjct: 162 FFQMAKALQYLHSHDIAHRDLKCENILLS-KRLNVKIADFGFARY 31
>06358
Length = 1517
Score = 33.9 bits (76), Expect = 0.068, Method: Compositional matrix adjust.
Identities = 42/162 (25%), Positives = 76/162 (46%), Gaps = 31/162 (19%)
Frame = +3
Query: 1 MYEILKALDYCHS-MGIMHRDVKPHNVMIDHEHRKLRLIDWGLA--EFY----------- 46
+ ++ +AL + H+ +MHR+V P +M+ +L W LA EF
Sbjct: 378 LLQVTEALGFLHNDAKMMHRNVCPEAIMLT------KLGSWKLAGYEFCVRSSDPQSTDP 539
Query: 47 -HPGQEYNVRVASRY-----FKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGH 100
+P E+ +A F PE ++ Q S DM+SLG ++ S+ + +P F +
Sbjct: 540 SYPFYEWRSDIAPVTQPHLDFMAPEYVLTMQCGTGS-DMFSLGLLVYSVFAKGKPLFECN 716
Query: 101 -------DNYDQL--VRIAKVLGT--EDLYDYIDKYNIELDP 131
N ++L +R++ +LG EDL D++ K + ++P
Sbjct: 717 GELSAFKSNAEELRHMRVS-LLGVVPEDLRDHV-KLLLNIEP 836
>29590
Length = 320
Score = 33.5 bits (75), Expect = 0.088, Method: Compositional matrix adjust.
Identities = 18/58 (31%), Positives = 28/58 (48%)
Frame = +3
Query: 39 DWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPF 96
D G A + G++ + + + PE+L DY+ DMWSLG + M+ PF
Sbjct: 6 DLGFACLTNTGEDIRDIIGTPDYVAPEVL-DYEPLSIQTDMWSLGVLSYVMLTACSPF 176
>15931
Length = 447
Score = 33.1 bits (74), Expect = 0.10, Method: Compositional matrix adjust.
Identities = 12/29 (41%), Positives = 20/29 (68%)
Frame = +1
Query: 160 EALDFLDKLLRYDHQSRLTAREAMEHPYF 188
+ D +DK+L Y+ +R + R+AM HP+F
Sbjct: 70 QLFDLMDKMLSYEVSTRYSLRQAMRHPFF 156
>11801
Length = 743
Score = 32.7 bits (73), Expect = 0.13, Method: Compositional matrix adjust.
Identities = 26/93 (27%), Positives = 49/93 (52%), Gaps = 3/93 (3%)
Frame = -1
Query: 79 MWSLGCMLASMIFRKEPFFHGHDNYDQLVR---IAKVLGTEDLYDYIDKYNIELDPRFND 135
++S G L +++ +K P YDQL R +AKV+ + D++ I+LDP+++
Sbjct: 302 VFSGGTALRTLL-KKFPVTSSSIPYDQLQRRCSVAKVVSETSCCKFGDQF-IKLDPQYDY 129
Query: 136 ILGRHSRKRWERFVHSENQHLVSPEALDFLDKL 168
+ ++S + R+ QH+ +AL F D +
Sbjct: 128 RVAKYSYLQSYRYFDDHKQHIR--QALMFNDTI 36
>26909
Length = 394
Score = 32.7 bits (73), Expect = 0.14, Method: Compositional matrix adjust.
Identities = 29/109 (26%), Positives = 43/109 (39%), Gaps = 10/109 (9%)
Frame = +2
Query: 90 IFRKEPFFHGHD---------NYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRH 140
+ EP FH ++DQL RI V+G D+ D + + R
Sbjct: 14 LLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFPQEKDWEDIRRMPEHQQLTKDFKRS 193
Query: 141 SRKRWERFVHSENQHL-VSPEALDFLDKLLRYDHQSRLTAREAMEHPYF 188
S + E + +A L KLL D R+T+ +AM+ PYF
Sbjct: 194 SYVNCNLMKYMEKHKVKADSKAFHLLQKLLTMDPVKRITSEQAMKDPYF 340
>14104
Length = 573
Score = 31.6 bits (70), Expect = 0.29, Method: Compositional matrix adjust.
Identities = 11/31 (35%), Positives = 19/31 (61%)
Frame = +1
Query: 157 VSPEALDFLDKLLRYDHQSRLTAREAMEHPY 187
+P+A+ F+ L+ D RLT + ++HPY
Sbjct: 88 AAPQAMSFMQSCLKMDPAERLTCHQLLQHPY 180
>28157
Length = 400
Score = 31.6 bits (70), Expect = 0.31, Method: Compositional matrix adjust.
Identities = 15/44 (34%), Positives = 26/44 (59%), Gaps = 3/44 (6%)
Frame = +3
Query: 7 ALDYCHSM---GIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYH 47
++Y H M ++HRD+KP N+++ KL++ D+G A H
Sbjct: 252 GVEYLHGMKPKALIHRDLKPPNLLLIQCGTKLKICDFGTACDIH 383
>12672
Length = 773
Score = 31.2 bits (69), Expect = 0.43, Method: Compositional matrix adjust.
Identities = 23/88 (26%), Positives = 41/88 (46%), Gaps = 3/88 (3%)
Frame = +3
Query: 6 KALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPE 65
+ Y + G +HRD+K N+++D E+ ++ D+ G+ V+ AS
Sbjct: 24 SGIQYLNDNGHVHRDIKTANILLDSEYTA-KVGDFATVVSAPSGEGKTVQNASVVIGTAA 200
Query: 66 LLVDYQM-YDYS--LDMWSLGCMLASMI 90
L + +D S LD +S G +L +I
Sbjct: 201 YLAPEAIHFDVSTKLDSYSFGVVLLEVI 284
>21800
Length = 855
Score = 30.8 bits (68), Expect = 0.60, Method: Compositional matrix adjust.
Identities = 18/55 (32%), Positives = 31/55 (56%), Gaps = 6/55 (10%)
Frame = +2
Query: 1 MYEILKALDYCHS-MGIMHRDVKPHNVMI---DHEHRKLRL--IDWGLAEFYHPG 49
+ ++L+ L+Y H+ I+H D+KP N++I D+ RKL + +W PG
Sbjct: 650 IRQVLEGLNYLHAKCNIIHTDIKPENILICVDDNYIRKLAVDAFEWQRLGLKLPG 814
>27274
Length = 396
Score = 30.4 bits (67), Expect = 0.65, Method: Compositional matrix adjust.
Identities = 30/126 (23%), Positives = 50/126 (39%)
Frame = -1
Query: 63 GPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYI 122
G ELL Q + ++DMWSLG +L ++ PF Q+ R +
Sbjct: 381 GAELLRG-QQHGPTVDMWSLGILLHELLSGHVPF-EPERGSRQMARNMMAV--------- 235
Query: 123 DKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREA 182
+ I+ SR + +S DFL +L++ + RLT+++A
Sbjct: 234 ----------YAQIIRGSSRDVCDGLA-------LSTHGADFLRRLVQLEDTKRLTSQQA 106
Query: 183 MEHPYF 188
HP+
Sbjct: 105 FSHPWI 88
>35032
Length = 465
Score = 30.0 bits (66), Expect = 0.92, Method: Compositional matrix adjust.
Identities = 12/27 (44%), Positives = 16/27 (59%)
Frame = +3
Query: 163 DFLDKLLRYDHQSRLTAREAMEHPYFY 189
D + +LL YD RLT A+ HP+ Y
Sbjct: 147 DLVKRLLNYDPSKRLTPXXALAHPFLY 227
>37063
Length = 455
Score = 30.0 bits (66), Expect = 1.0, Method: Compositional matrix adjust.
Identities = 23/78 (29%), Positives = 36/78 (46%), Gaps = 12/78 (15%)
Frame = -2
Query: 21 VKPHNVMIDH--EHRKLRLIDWGLAEFYH------PGQEYNVRVASRYFKGPELLVDYQ- 71
+KP N++ +H E L++ D+ LA + E V S + PE++ +
Sbjct: 454 LKPENILCEHLDEVVPLKICDFDLASGINCDGDGTKTPELLTPVGSAEYMAPEVVDAWVG 275
Query: 72 ---MYDYSLDMWSLGCML 86
YD DMWSLG +L
Sbjct: 274 ESFSYDKRCDMWSLGIIL 221
>17932
Length = 597
Score = 30.0 bits (66), Expect = 1.0, Method: Compositional matrix adjust.
Identities = 17/35 (48%), Positives = 22/35 (62%)
Frame = -3
Query: 157 VSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTV 191
VS EA D + +LL D +SRL E +HP+F TV
Sbjct: 460 VSKEARDLISQLLS-DGKSRLGWPELQQHPFFKTV 359
>16350
Length = 1108
Score = 29.3 bits (64), Expect = 1.4, Method: Compositional matrix adjust.
Identities = 10/26 (38%), Positives = 18/26 (69%)
Frame = +3
Query: 163 DFLDKLLRYDHQSRLTAREAMEHPYF 188
DFL +L +D + R TA ++++HP+
Sbjct: 762 DFLAPMLEFDPEQRATAAQSLQHPWL 839
>19301
Length = 712
Score = 29.3 bits (64), Expect = 1.6, Method: Compositional matrix adjust.
Identities = 13/41 (31%), Positives = 27/41 (65%)
Frame = +2
Query: 3 EILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLA 43
+I ++Y HS I+HRD+K NV++ ++ +++ D+G +
Sbjct: 593 QIASGMNYLHSHKIIHRDLKSPNVLV-AKNDVVKISDFGTS 712
>29360
Length = 363
Score = 28.9 bits (63), Expect = 1.9, Method: Compositional matrix adjust.
Identities = 10/26 (38%), Positives = 18/26 (69%)
Frame = +3
Query: 3 EILKALDYCHSMGIMHRDVKPHNVMI 28
++L AL +G++H D+KP N+M+
Sbjct: 282 QVLTALRKLKQLGLIHADLKPENIML 359
>20513
Length = 405
Score = 28.5 bits (62), Expect = 2.4, Method: Compositional matrix adjust.
Identities = 10/26 (38%), Positives = 18/26 (69%)
Frame = -1
Query: 163 DFLDKLLRYDHQSRLTAREAMEHPYF 188
DFL +L +D + R TA ++++HP+
Sbjct: 282 DFLAPMLEFDPEQRATAAQSLQHPWL 205
>18663
Length = 600
Score = 28.5 bits (62), Expect = 2.5, Method: Compositional matrix adjust.
Identities = 13/34 (38%), Positives = 21/34 (61%)
Frame = +2
Query: 63 GPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPF 96
PE+L + Y +S+D W+LG +L M+ + PF
Sbjct: 32 APEILRG-EDYGFSVDWWALGVLLYEMLAGRSPF 130
>28419
Length = 687
Score = 28.5 bits (62), Expect = 2.8, Method: Compositional matrix adjust.
Identities = 26/96 (27%), Positives = 43/96 (44%), Gaps = 5/96 (5%)
Frame = +3
Query: 4 ILKALDYCHSMG----IMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASR 59
ILK L YC ++ ++ K N+ EH K++ + G + +R S+
Sbjct: 342 ILKRLRYCLNLSKPPSYLNTVRKL*NISYVREHDKVKALMLGFKLLVNSQCANALRHPSQ 521
Query: 60 YFKGPELL-VDYQMYDYSLDMWSLGCMLASMIFRKE 94
KGPEL+ D+Q Y++ C+ + RKE
Sbjct: 522 I*KGPELIPYDFQFYEF-----PTACVTSPY*VRKE 614
>20773
Length = 391
Score = 28.1 bits (61), Expect = 3.2, Method: Compositional matrix adjust.
Identities = 16/50 (32%), Positives = 25/50 (50%)
Frame = -1
Query: 138 GRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPY 187
G H R+ F H+ +V+ + + +LL YD RLT A+ HP+
Sbjct: 370 GLHRRRSRPVFPHTT---VVTQHFYNLVQRLLTYDPSQRLTPDLALSHPF 230
>32359
Length = 928
Score = 28.1 bits (61), Expect = 3.2, Method: Compositional matrix adjust.
Identities = 9/17 (52%), Positives = 14/17 (82%)
Frame = -3
Query: 15 GIMHRDVKPHNVMIDHE 31
G+ HRD+KP N+++D E
Sbjct: 65 GVCHRDIKPQNLLLDPE 15
>20152
Length = 445
Score = 28.1 bits (61), Expect = 4.0, Method: Compositional matrix adjust.
Identities = 12/39 (30%), Positives = 23/39 (58%)
Frame = +1
Query: 64 PELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDN 102
PE+L+ ++D+WSLG +L ++ + PF +D+
Sbjct: 1 PEILLGDSYDAPAVDVWSLGVILYMLVVGEAPFQEANDS 117
>01106
Length = 878
Score = 27.7 bits (60), Expect = 4.3, Method: Compositional matrix adjust.
Identities = 11/29 (37%), Positives = 20/29 (68%), Gaps = 1/29 (3%)
Frame = +3
Query: 1 MYEILKALDYCHSMG-IMHRDVKPHNVMI 28
+ ++L+ L Y H+ I+H D+KP N++I
Sbjct: 663 IRQVLEGLSYMHAKCRIIHTDIKPENILI 749
>21210
Length = 518
Score = 27.7 bits (60), Expect = 4.4, Method: Compositional matrix adjust.
Identities = 17/78 (21%), Positives = 36/78 (46%), Gaps = 12/78 (15%)
Frame = +3
Query: 73 YDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLG---------TEDLYDYID 123
YD D+WSLG L + + P+ +DQL ++ + + + D ++++
Sbjct: 63 YDVRSDVWSLGITLMELATGRFPYRKWVSIFDQLQQVVRGVAPCLPHDGAFSHDFVNFVN 242
Query: 124 KY---NIELDPRFNDILG 138
K + + P++N +L
Sbjct: 243 KCLTKDEKQRPKYNKLLA 296
>37603
Length = 1005
Score = 27.3 bits (59), Expect = 6.7, Method: Compositional matrix adjust.
Identities = 10/25 (40%), Positives = 14/25 (56%)
Frame = +2
Query: 2 YEILKALDYCHSMGIMHRDVKPHNV 26
Y + L +CH GI RD +PH +
Sbjct: 551 YHVRIQLSFCHVEGIKRRDGRPHAI 625
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000311032 | hsapiens_gene_ensembl | Caspase-3
precursor (EC 3.4.22.56) (CASP-3) (Apopain) (Cysteine protease CPP32)
(Yama protein) (CPP-32) (SREBP cleavage activity 1) (SCA-1) [Contains:
Caspase-3 p17 subunit; Caspase-3 p12 subunit].
[Source:Uniprot/SWISSPROT;Acc:P42574]
(277 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
09057 193 7e-50
09018 122 2e-28
34700 50 1e-06
28497 27 7.2
>09057
Length = 1545
Score = 193 bits (490), Expect = 7e-50, Method: Compositional matrix adjust.
Identities = 98/244 (40%), Positives = 142/244 (58%), Gaps = 5/244 (2%)
Frame = -3
Query: 37 YKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEI 96
Y M + G+ +I N+++F T + +R+GT+VD NL + L ++V D EI
Sbjct: 1315 YNMRHKHRGMALIFNHEHFDVPT-LKARAGTNVDCENLTRVLKQLDFDVTVYKDCRYTEI 1139
Query: 97 VELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPK 156
+ ++ + ++H + +LSHGE G I+ + L I + F + C +L GKPK
Sbjct: 1138 LSTVKYXASQNHENNDCILVAILSHGEMGYIYAKDTHYKLDNIWSHFTANHCPTLAGKPK 959
Query: 157 LFIIQACRGTELDCGIETDSGV----DDDMACHKIPVEADFLYAYSTAPGYYSWRNSKDG 212
LF IQAC+G LD G+ G D +KIP+ ADFL AYST PG+YSWRN+ G
Sbjct: 958 LFFIQACQGDHLDTGVTMQRGRTETDGDSTMSYKIPIHADFLIAYSTIPGFYSWRNTTRG 779
Query: 213 SWFIQSLCAMLKQYADKLEFMHILTRVNRKVATEFESFSFDAT-FHAKKQIPCIVSMLTK 271
SWF+QSLCA L +L+ + +LT V ++VA +FES + D H +KQIPCI +MLT+
Sbjct: 778 SWFMQSLCAELAANGKRLDILTLLTFVCQRVAVDFESCTPDTPEMHQQKQIPCITTMLTR 599
Query: 272 ELYF 275
L F
Sbjct: 598 ILLF 587
>09018
Length = 1857
Score = 122 bits (305), Expect = 2e-28, Method: Compositional matrix adjust.
Identities = 73/195 (37%), Positives = 108/195 (55%), Gaps = 13/195 (6%)
Frame = -3
Query: 63 SRSGTDVDAANLRETFRNLKYEV---RNKNDLTREEIVELMRDVSKE-DHSKRSSFVCVL 118
R GTDVD NL R L ++V +++DLT + E +R +K+ +H + V L
Sbjct: 1828 PRRGTDVDRDNLTNLLRQLHFQVTIYNDEDDLTALGMAEKLRAFAKKVEHQSADACVICL 1649
Query: 119 LSHGEEGIIFGTNGP-VDLKKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGI----- 172
LSHGEE +FGT+G + L ++ F C +L KPK+F IQACRG LD G+
Sbjct: 1648 LSHGEEKYMFGTDGKKIPLDEVFLLFDNRHCPALINKPKIFFIQACRGGMLDQGVKVKLD 1469
Query: 173 ETDSGV---DDDMACHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADK 229
E D G +++M H P +D L Y T GYY+WRN + GSW+I+++ + ++A
Sbjct: 1468 EPDGGPPGHNNNMQQH--PSMSDMLICYPTLQGYYAWRNREKGSWYIEAVVKVFMKHAKC 1295
Query: 230 LEFMHILTRVNRKVA 244
+ +L RVN V+
Sbjct: 1294 EDICAMLNRVNSDVS 1250
>34700
Length = 459
Score = 49.7 bits (117), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 29/101 (28%), Positives = 53/101 (52%), Gaps = 6/101 (5%)
Frame = -2
Query: 64 RSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRS-SFVCVLLSHG 122
R+G D D A L FR + + + + +L ++E + + ++ ++ + + SFV VL++HG
Sbjct: 317 RNGADNDGAALIHIFRQMDFTIFSYKNLEQDEFFKTLDILTSSEYVRATESFVMVLMTHG 138
Query: 123 E-----EGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPKLF 158
E + + F D+K I F+ D C +L KPK+
Sbjct: 137 ERVKEVDKVQFTNGSFCDVKNIIKHFQPDVCPNLIDKPKVL 15
>28497
Length = 734
Score = 27.3 bits (59), Expect = 7.2, Method: Compositional matrix adjust.
Identities = 20/95 (21%), Positives = 33/95 (34%)
Frame = +3
Query: 126 IIFGTNGPVDLKKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIETDSGVDDDMACH 185
+I P + ++ NF ++ GKP ++ C+ T
Sbjct: 312 VIQWMQNPRTISEVKNFEPWREKCTVEGKPVCWVPNTCKLTS-----------------K 440
Query: 186 KIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLC 220
++P E L P Y W N G F +S+C
Sbjct: 441 EVPGETINLQTCVRCPNNYPWLNDPTGDGFSKSVC 545
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000377213 | hsapiens_gene_ensembl | Caspase-3
precursor (EC 3.4.22.56) (CASP-3) (Apopain) (Cysteine protease CPP32)
(Yama protein) (CPP-32) (SREBP cleavage activity 1) (SCA-1) [Contains:
Caspase-3 p17 subunit; Caspase-3 p12 subunit].
[Source:Uniprot/SWISSPROT;Acc:P42574]
(277 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
09057 193 7e-50
09018 122 2e-28
34700 50 1e-06
28497 27 7.2
>09057
Length = 1545
Score = 193 bits (490), Expect = 7e-50, Method: Compositional matrix adjust.
Identities = 98/244 (40%), Positives = 142/244 (58%), Gaps = 5/244 (2%)
Frame = -3
Query: 37 YKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEI 96
Y M + G+ +I N+++F T + +R+GT+VD NL + L ++V D EI
Sbjct: 1315 YNMRHKHRGMALIFNHEHFDVPT-LKARAGTNVDCENLTRVLKQLDFDVTVYKDCRYTEI 1139
Query: 97 VELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPK 156
+ ++ + ++H + +LSHGE G I+ + L I + F + C +L GKPK
Sbjct: 1138 LSTVKYXASQNHENNDCILVAILSHGEMGYIYAKDTHYKLDNIWSHFTANHCPTLAGKPK 959
Query: 157 LFIIQACRGTELDCGIETDSGV----DDDMACHKIPVEADFLYAYSTAPGYYSWRNSKDG 212
LF IQAC+G LD G+ G D +KIP+ ADFL AYST PG+YSWRN+ G
Sbjct: 958 LFFIQACQGDHLDTGVTMQRGRTETDGDSTMSYKIPIHADFLIAYSTIPGFYSWRNTTRG 779
Query: 213 SWFIQSLCAMLKQYADKLEFMHILTRVNRKVATEFESFSFDAT-FHAKKQIPCIVSMLTK 271
SWF+QSLCA L +L+ + +LT V ++VA +FES + D H +KQIPCI +MLT+
Sbjct: 778 SWFMQSLCAELAANGKRLDILTLLTFVCQRVAVDFESCTPDTPEMHQQKQIPCITTMLTR 599
Query: 272 ELYF 275
L F
Sbjct: 598 ILLF 587
>09018
Length = 1857
Score = 122 bits (305), Expect = 2e-28, Method: Compositional matrix adjust.
Identities = 73/195 (37%), Positives = 108/195 (55%), Gaps = 13/195 (6%)
Frame = -3
Query: 63 SRSGTDVDAANLRETFRNLKYEV---RNKNDLTREEIVELMRDVSKE-DHSKRSSFVCVL 118
R GTDVD NL R L ++V +++DLT + E +R +K+ +H + V L
Sbjct: 1828 PRRGTDVDRDNLTNLLRQLHFQVTIYNDEDDLTALGMAEKLRAFAKKVEHQSADACVICL 1649
Query: 119 LSHGEEGIIFGTNGP-VDLKKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGI----- 172
LSHGEE +FGT+G + L ++ F C +L KPK+F IQACRG LD G+
Sbjct: 1648 LSHGEEKYMFGTDGKKIPLDEVFLLFDNRHCPALINKPKIFFIQACRGGMLDQGVKVKLD 1469
Query: 173 ETDSGV---DDDMACHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADK 229
E D G +++M H P +D L Y T GYY+WRN + GSW+I+++ + ++A
Sbjct: 1468 EPDGGPPGHNNNMQQH--PSMSDMLICYPTLQGYYAWRNREKGSWYIEAVVKVFMKHAKC 1295
Query: 230 LEFMHILTRVNRKVA 244
+ +L RVN V+
Sbjct: 1294 EDICAMLNRVNSDVS 1250
>34700
Length = 459
Score = 49.7 bits (117), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 29/101 (28%), Positives = 53/101 (52%), Gaps = 6/101 (5%)
Frame = -2
Query: 64 RSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRS-SFVCVLLSHG 122
R+G D D A L FR + + + + +L ++E + + ++ ++ + + SFV VL++HG
Sbjct: 317 RNGADNDGAALIHIFRQMDFTIFSYKNLEQDEFFKTLDILTSSEYVRATESFVMVLMTHG 138
Query: 123 E-----EGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPKLF 158
E + + F D+K I F+ D C +L KPK+
Sbjct: 137 ERVKEVDKVQFTNGSFCDVKNIIKHFQPDVCPNLIDKPKVL 15
>28497
Length = 734
Score = 27.3 bits (59), Expect = 7.2, Method: Compositional matrix adjust.
Identities = 20/95 (21%), Positives = 33/95 (34%)
Frame = +3
Query: 126 IIFGTNGPVDLKKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIETDSGVDDDMACH 185
+I P + ++ NF ++ GKP ++ C+ T
Sbjct: 312 VIQWMQNPRTISEVKNFEPWREKCTVEGKPVCWVPNTCKLTS-----------------K 440
Query: 186 KIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLC 220
++P E L P Y W N G F +S+C
Sbjct: 441 EVPGETINLQTCVRCPNNYPWLNDPTGDGFSKSVC 545
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000261793 | hsapiens_gene_ensembl |
Calcium/calmodulin-dependent protein kinase type II alpha chain (EC
2.7.11.17) (CaM-kinase II alpha chain) (CaM kinase II alpha subunit)
(CaMK-II subunit alpha). [Source:Uniprot/SWISSPROT;Acc:Q9UQM7]
(529 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
15910 194 8e-50
01392 124 1e-28
12721 122 3e-28
01707 106 2e-23
01060 104 1e-22
09606 103 2e-22
03240 102 5e-22
30755 101 9e-22
21079 92 9e-22
17975 99 3e-21
13592 99 5e-21
18484 97 2e-20
14420 95 6e-20
26711 93 3e-19
14126 92 6e-19
00300 90 2e-18
21433 75 1e-16
13212 80 1e-15
13066 76 3e-14
09007 75 6e-14
01966 71 1e-12
31885 70 2e-12
00392 70 3e-12
28638 64 3e-12
00486 68 7e-12
01718 68 8e-12
27405 67 1e-11
19761 67 1e-11
38560 66 4e-11
06405 65 8e-11
18921 65 9e-11
21808 64 2e-10
26560 64 2e-10
29581 64 2e-10
21418 62 4e-10
36002 61 1e-09
20152 61 1e-09
12786 60 2e-09
29590 45 2e-09
04591 59 4e-09
01756 59 4e-09
19094 50 5e-09
27546 56 3e-08
11185 55 5e-08
18663 55 5e-08
04138 55 6e-08
27274 55 7e-08
20655 55 7e-08
31120 53 3e-07
02638 52 5e-07
17300 52 7e-07
32000 52 7e-07
04852 51 1e-06
19301 51 1e-06
03508 50 2e-06
17722 49 5e-06
28157 49 5e-06
14116 49 5e-06
00715 47 1e-05
11780 47 2e-05
36481 47 3e-05
00394 46 3e-05
31789 46 4e-05
31489 45 6e-05
25019 45 8e-05
07291 44 1e-04
18481 44 2e-04
32957 41 0.001
07940 41 0.001
08294 41 0.001
12672 41 0.002
01106 41 0.002
18287 40 0.003
29360 39 0.005
11404 39 0.006
23319 39 0.006
18401 38 0.009
20513 37 0.019
37063 37 0.019
18996 37 0.020
16350 37 0.024
15549 36 0.035
07836 36 0.041
16708 35 0.053
00638 35 0.053
20559 35 0.073
20160 35 0.11
37602 34 0.17
32359 34 0.19
26009 33 0.23
35032 33 0.39
33586 32 0.50
17516 32 0.70
21800 32 0.78
03106 31 1.2
13305 31 1.2
03294 30 2.0
17011 30 3.6
28494 29 5.5
14104 28 6.3
32357 28 7.0
32691 28 8.7
>15910
Length = 1361
Score = 194 bits (493), Expect = 8e-50, Method: Compositional matrix adjust.
Identities = 100/207 (48%), Positives = 133/207 (64%)
Frame = +2
Query: 147 ELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLA 206
ELF+ IV R Y+E DA+ I IL V + H GVVHRDLKPENLL + +KLA
Sbjct: 422 ELFDRIVTRGQYTEKDAARAISDILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLA 601
Query: 207 DFGLAIEVEGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWD 266
DFGL+ +E E Q GTPGY +PEVL+ D Y VD+W+ GVI YILL GY PF+
Sbjct: 602 DFGLSRIIEPEVQM-STVCGTPGYCAPEVLKGDKYTPSVDMWSVGVIAYILLCGYEPFFA 778
Query: 267 EDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPSKRITAAEALKHPWISHRS 326
E++ +Y++I G Y F W ++ AKD++ K+L I+P KR+TA EAL+ PW+ +
Sbjct: 779 ENEFEMYRKIIKGEYKFDEEYWSEISENAKDVVRKLLVIDPKKRLTATEALRLPWVKGVA 958
Query: 327 TVASCMHRQETVDCLKKFNARRKLKGA 353
T + M + T++ LK+FNARRKLK A
Sbjct: 959 TKTTNM--EITMNKLKEFNARRKLKCA 1033
>01392
Length = 1806
Score = 124 bits (310), Expect = 1e-28, Method: Compositional matrix adjust.
Identities = 74/191 (38%), Positives = 100/191 (52%), Gaps = 25/191 (13%)
Frame = -1
Query: 157 YYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLA--IEV 214
+ E +AS ++ I A+ H G+ HRDLKPEN+L VK+ DF LA I
Sbjct: 1803 HLCEREASLVVRHIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGISC 1624
Query: 215 EGEQQA---WFGFAGTPGYLSPEVLR-----KDPYGKPVDLWACGVILYILLVGYPPFWD 266
+G+ G+ Y++PEV+ Y K DLW+ G+ILYI+L GYPPF+
Sbjct: 1623 DGDGTKTPELLTPVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILYIMLCGYPPFYG 1444
Query: 267 ---ED------------QHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPSKRI 311
ED Q L+ I+ G Y FPS EW +++ AKDLI +L P KR
Sbjct: 1443 QCGEDCGWNRGEACHDCQDMLFNSIQDGHYKFPSQEWTSISSSAKDLIRHLLVREPRKRY 1264
Query: 312 TAAEALKHPWI 322
+AA+ LKHPWI
Sbjct: 1263 SAADVLKHPWI 1231
>12721
Length = 821
Score = 122 bits (307), Expect = 3e-28, Method: Compositional matrix adjust.
Identities = 75/251 (29%), Positives = 134/251 (53%), Gaps = 4/251 (1%)
Frame = +1
Query: 67 FEELGKGAFSVVRRCVKV-LAGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVR 125
F ++G+G+ +V C+ G++ A K ++ +K R + L E + R HPNIV
Sbjct: 103 FMKIGEGSTGIV--CIATSRDGRQMAVKKMDLRKQQRR--ELLFNEVVVMRDYHHPNIVE 270
Query: 126 LHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHR 185
+++S +++ + + GG L DIV E + + L+A+ H GV+HR
Sbjct: 271 MYNSYLVNDELWVVMEFMEGGAL-TDIVTNNRMDEVQIATVCRACLKALAFLHANGVIHR 447
Query: 186 DLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSPEVLRKDPYGKPV 245
D+K +++LL+ K VKL DFG +V + Q GTP +++PEV+ + PYG V
Sbjct: 448 DIKSDSILLSHDGK---VKLXDFGFCAQVTQDLQKRKSLVGTPYWMAPEVISRLPYGPEV 618
Query: 246 DLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT---VTPEAKDLINKM 302
D+W+ G+++ ++ PPF++E + ++I+ D P P+ ++P + I++M
Sbjct: 619 DIWSLGIMVMEMIDAEPPFFNEPPLQAMRRIR----DMPPPKLRNTHKISPRLQGFIDRM 786
Query: 303 LTINPSKRITA 313
L +P +R TA
Sbjct: 787 LVRDPHQRATA 819
>01707
Length = 757
Score = 106 bits (265), Expect = 2e-23, Method: Compositional matrix adjust.
Identities = 74/218 (33%), Positives = 106/218 (48%), Gaps = 4/218 (1%)
Frame = +1
Query: 62 EEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLKHP 121
E+Y+ ++G+G++ VV +C Q A K + + RE R+ + LKHP
Sbjct: 64 EKYEKIGKIGEGSYGVVFKCRNKETSQLVAIKKFVESEDDPLIKKIAMREIRMLKQLKHP 243
Query: 122 NIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMG 181
N+VRL + + +L+FD V L E E I Q L AV CHQ
Sbjct: 244 NLVRLIEVFRRKKRLHLVFDYVDHTLLNELDRYPRGLPEPMVKRIIYQTLLAVNFCHQYN 423
Query: 182 VVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSPEVLRKDP- 240
+HRD+KPEN+L+ + VKL DFG A + G + + T Y +PE+L D
Sbjct: 424 TIHRDVKPENILITRQ---GQVKLCDFGFARILTGPGDEYTDYVATRWYRAPELLVGDTQ 594
Query: 241 YGKPVDLWACGVILYILLVG---YPPFWDEDQHRLYQQ 275
YG PVD+WA G + LL G +P D DQ L ++
Sbjct: 595 YGPPVDVWAIGCVFAELLTGQALWPGRSDVDQLHLIRK 708
>01060
Length = 1800
Score = 104 bits (259), Expect = 1e-22, Method: Compositional matrix adjust.
Identities = 87/329 (26%), Positives = 148/329 (44%), Gaps = 44/329 (13%)
Frame = +1
Query: 43 SLTCLPSARMATITCTRFTEEYQL-------FEELGKGAFSVVRRCVKVLAGQEYAAKII 95
+LTCL + + R +++ F+++G+G + VV +C G++ A K I
Sbjct: 7 TLTCL----LLKLNIKRLMMDFETALSDLTDFQKIGEGTYGVVYKCRHRATGRKLAMKKI 174
Query: 96 NTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGHHYLIFDLVTG---------- 145
+ RE + R L+H NIV L D I E+ +L+F+ ++
Sbjct: 175 RLRGSEDGVPSSAIREIAMLRELRHTNIVCLEDVIMEDERLFLVFEFLSMDLKMYIDKFP 354
Query: 146 -GELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVK 204
G + + + + Y + QI+ + CHQ +VHRDLKP+NLL+ A+K
Sbjct: 355 EGVVLDRRLVKSY---------VFQIVTGIXFCHQRRIVHRDLKPQNLLINHT---GAIK 498
Query: 205 LADFGLAIEVEGEQQAWFGFAGTPGYLSPEVLR-KDPYGKPVDLWACGVILYILLVGYPP 263
+ADFG+A +A+ T Y +PE+L Y PVD+W+ G I +L+ P
Sbjct: 499 IADFGMARTFALPVRAYTHEVVTLWYRAPEILMGASKYSTPVDVWSIGTIFADMLIRTPI 678
Query: 264 F-WDEDQHRLYQQI---------------KAGAYDFPSPEW------DTVT---PEAKDL 298
F D + +L++ K A++ P W +T+T DL
Sbjct: 679 FKGDSEIDQLFKIFRIIGTPTEQTWPEFHKLPAFNGMFPLWKEGKLSETLTDLDSLGLDL 858
Query: 299 INKMLTINPSKRITAAEALKHPWISHRST 327
I + L +P++RI+ + L+H + + T
Sbjct: 859 IERTLKCDPAQRISCKKMLQHAYFLNVDT 945
>09606
Length = 1300
Score = 103 bits (256), Expect = 2e-22, Method: Compositional matrix adjust.
Identities = 75/286 (26%), Positives = 134/286 (46%), Gaps = 28/286 (9%)
Frame = -3
Query: 62 EEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLKHP 121
E + L+EELGKG S++ + + A I K ++ R+ + HP
Sbjct: 1115 ENFVLYEELGKGEHSIIYKGRRKGTINFVAIHCIEKCK-----RPEVTNTVRMTHDISHP 951
Query: 122 NIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYY-SEADASHCIQQILEAVLHCHQM 180
N+V+ H+ H +L+ +L TGG L DI+A++++ E ++ + + H +
Sbjct: 950 NVVQFHEWYETSNHLWLVVELCTGGSL-ADILAQDHHLPETSIRDFGIHLVTGLHYIHSL 774
Query: 181 GVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGE--QQAWFGFA------------- 225
G++ DL+P +LL + +K ADFGL+ +VEGE ++ +F FA
Sbjct: 773 GILFHDLRPSKVLLDTS---GVLKFADFGLS-KVEGENLEELFFKFAEAGDQWNIQSAEE 606
Query: 226 --------GTPGYLSPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIK 277
G+P Y++PEV + DLWA G + Y + G+PPF E ++
Sbjct: 605 MMKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSGHPPFLGETYDITKDKVL 426
Query: 278 AGAYDFPSPEWDTV----TPEAKDLINKMLTINPSKRITAAEALKH 319
+ P + + +PE +L+ +L + ++R++ A +KH
Sbjct: 425 NKEFPLPKVKGSRLSAKPSPEFLNLLESLLQKDSTRRLSWASLVKH 288
>03240
Length = 1683
Score = 102 bits (253), Expect = 5e-22, Method: Compositional matrix adjust.
Identities = 79/287 (27%), Positives = 127/287 (44%), Gaps = 48/287 (16%)
Frame = -3
Query: 64 YQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARD---HQKLEREARICRLLKH 120
++ + LG GAF V C K G YA K + + R+ H K ER+ I +
Sbjct: 1285 FEKIKTLGVGAFGEVSLCRKNDTGMLYAMKTLRKSDVLKRNQVAHVKAERD--ILAEADN 1112
Query: 121 PNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQM 180
+V+L+ S + + Y + D V GG+L ++ E E A + ++++A+ H+M
Sbjct: 1111 EWVVKLYYSFQDHNYLYFVMDYVPGGDLMGLLIRMEILDEPLARFYVAELVQAIESVHRM 932
Query: 181 GVVHRDLKPENLLLASKLKGAAVKLADFGL-----------------------AIEV--- 214
G +HRD+KP+N+L+ + +KL DFGL ++EV
Sbjct: 931 GFIHRDIKPDNILID---RNGHIKLTDFGLCTGFRWTHNSKYYQRDGTHARQDSMEVKCQ 761
Query: 215 -----------------EGEQQAW-FGFAGTPGYLSPEVL-RKDPYGKPVDLWACGVILY 255
+ EQ+ GTP Y++PEVL R Y D W+ GVIL+
Sbjct: 760 LDEQCQCEILKPLERRRKREQRCLAHSLVGTPNYIAPEVLSRLGGYTSVCDWWSVGVILF 581
Query: 256 ILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKM 302
+LVG+PPF+ ++ P ++ AKDLI ++
Sbjct: 580 EMLVGHPPFYANTPAETQYKVINWKDMLKIPRESNLSQPAKDLILRL 440
>30755
Length = 1137
Score = 101 bits (251), Expect = 9e-22, Method: Compositional matrix adjust.
Identities = 58/160 (36%), Positives = 86/160 (53%), Gaps = 5/160 (3%)
Frame = +2
Query: 169 QILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTP 228
+I+ A+ + H G+++RDLK ENLLL K +K+ADFGL E + F GTP
Sbjct: 56 EIISALGYLHSQGIIYRDLKLENLLLD---KDGHIKVADFGLCKEDITYGRTTKTFCGTP 226
Query: 229 GYLSPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEW 288
YL+PEVL + YG+ VD W GV++Y ++ G PF++ D L+ I FP
Sbjct: 227 EYLAPEVLDDNDYGRAVDWWGTGVVMYEMICGRLPFYNRDHDVLFTLILVEDVKFPR--- 397
Query: 289 DTVTPEAKDLINKMLTINPSKRITAA-----EALKHPWIS 323
+T EAK L++ +L +P R+ E HP+ +
Sbjct: 398 -NITDEAKSLLSGLLAKDPRNRLGGGQDDVKEIQAHPFFA 514
>21079
Length = 878
Score = 92.4 bits (228), Expect(2) = 9e-22, Method: Compositional matrix adjust.
Identities = 52/145 (35%), Positives = 77/145 (53%), Gaps = 1/145 (0%)
Frame = +1
Query: 120 HPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREY-YSEADASHCIQQILEAVLHCH 178
HP ++ L D+ L+ + V GELFE ++ ++ +E D H ++QI V + H
Sbjct: 1 HPKLLMLWDAFEAPRTMVLVMEFVGAGELFERVIRDDFVLTERDCVHFVRQICSGVGYMH 180
Query: 179 QMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSPEVLRK 238
++H DLKPEN+L S +K+ DFGLA + F GTP +++PEV+
Sbjct: 181 TQSILHLDLKPENVLCVSD-NSNQIKIIDFGLARFYKPGDSLQVLF-GTPEFIAPEVVNY 354
Query: 239 DPYGKPVDLWACGVILYILLVGYPP 263
D D+W+ GVI YILL G P
Sbjct: 355 DEINFTTDMWSIGVICYILLSGLSP 429
Score = 29.3 bits (64), Expect(2) = 9e-22, Method: Compositional matrix adjust.
Identities = 18/56 (32%), Positives = 27/56 (48%)
Frame = +2
Query: 294 EAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRK 349
AKD I + KR+T + KH W++ + C ++ D L+ F ARRK
Sbjct: 518 NAKDFIGNC*SREKEKRMTIEQCDKHSWLAEQDQRIRC--KRLNTDRLRCFMARRK 679
>17975
Length = 449
Score = 99.4 bits (246), Expect = 3e-21, Method: Composition-based stats.
Identities = 53/138 (38%), Positives = 82/138 (59%), Gaps = 1/138 (0%)
Frame = +3
Query: 75 FSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEG 134
F+VV+ V G++ A K+I+ KL L +E R +L++HPN+VRL++ I +
Sbjct: 6 FAVVKLARHVFTGEKVAVKVIDKTKLDEVSRSHLFQEVRCMKLVQHPNVVRLYEVIDTQT 185
Query: 135 HHYLIFDLVTGGELFEDIVARE-YYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLL 193
YLI +L GG++++ I+ E A +QI+EA+ +CH++ VVHRDLKPEN++
Sbjct: 186 KLYLILELGDGGDMYDYIMRHSGGLEEKLAKRYFRQIVEAISYCHKLHVVHRDLKPENVV 365
Query: 194 LASKLKGAAVKLADFGLA 211
K VKL DFG +
Sbjct: 366 FFE--KPGLVKLTDFGFS 413
>13592
Length = 980
Score = 98.6 bits (244), Expect = 5e-21, Method: Compositional matrix adjust.
Identities = 77/264 (29%), Positives = 126/264 (47%), Gaps = 11/264 (4%)
Frame = +2
Query: 69 ELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHD 128
++G+G F V V G+ A K I + R + + E +I +KH N+VR +
Sbjct: 5 KIGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETRALKNVAEELKILEGIKHKNLVRYY- 181
Query: 129 SISEEGHHYLIF-DLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDL 187
I LIF +L + G L + EA + Q+L V H+ G+VHRD+
Sbjct: 182 GIEVHREELLIFMELCSEGTLESLVELTGGLPEALSRRFTAQLLSGVAELHKHGIVHRDI 361
Query: 188 KPENLLLASKLKGAAVKLADFGLAIEVE------GEQQAWFGFAGTPGYLSPEVLRK--- 238
K N+ L ++KL DFG A++++ GE Q G+ GT Y++PEV K
Sbjct: 362 KTANIFLVD--GSNSLKLGDFGSAVKIQAHTTVPGELQ---GYVGTQAYMAPEVFTKTNS 526
Query: 239 DPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFP-SPEWDTVTPEAKD 297
D +G+ D+W+ G ++ + G P W + K G + P +PE +++ E D
Sbjct: 527 DGHGRLADIWSVGCVVVEMASGKRP-WAQFDSNFQIMFKVGMGEKPQAPE--SLSQEGHD 697
Query: 298 LINKMLTINPSKRITAAEALKHPW 321
I+ L +P +R++A E L+ +
Sbjct: 698 FIDHCLQHDPKQRLSAIELLEQNF 769
>18484
Length = 635
Score = 96.7 bits (239), Expect = 2e-20, Method: Compositional matrix adjust.
Identities = 53/154 (34%), Positives = 82/154 (53%)
Frame = +1
Query: 158 YSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGE 217
+ E A+ +I + H G+++RDLK +N++L S+ +K+ADFG+ E
Sbjct: 34 FKEPVAAFYAAEIAVGLFFLHDQGIIYRDLKLDNVMLDSE---GHIKIADFGMCKEGMTG 204
Query: 218 QQAWFGFAGTPGYLSPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIK 277
F GTP Y++PE++ PY K VD WA GV+L+ +L G PPF ED+ L+ I
Sbjct: 205 DATTRTFCGTPDYIAPEIVLYQPYSKSVDWWAYGVLLFEMLAGQPPFDGEDEDELFSSIT 384
Query: 278 AGAYDFPSPEWDTVTPEAKDLINKMLTINPSKRI 311
+P ++ EA L +L NP+KR+
Sbjct: 385 DHNVSYPK----AMSREAVSLCKGLLMKNPTKRL 474
>14420
Length = 528
Score = 95.1 bits (235), Expect = 6e-20, Method: Compositional matrix adjust.
Identities = 55/176 (31%), Positives = 93/176 (52%), Gaps = 1/176 (0%)
Frame = +2
Query: 97 TKKLSARDHQKLE-REARICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAR 155
T LS + ++L E + R ++PNIV DS +++ + + GG L D+V
Sbjct: 5 TMNLSQQPKKELIINEILVMRENQNPNIVNYLDSYLVGEELWVVMEFLAGGSL-TDVVTE 181
Query: 156 EYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVE 215
E + ++ L+A+ H+ V+HRD+K +N+LL +VKL DFG ++
Sbjct: 182 TCMDEGQIAAVCRECLQALEFLHENQVIHRDIKSDNILLGMD---GSVKLTDFGFCAQLS 352
Query: 216 GEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHR 271
EQ GTP +++PEV+ + YG VD+W+ GV+ ++ G PP+ +E+ R
Sbjct: 353 PEQSKRSTMVGTPYWMAPEVVTRKQYGPTVDIWSLGVMCIEMIEGEPPYLNENPLR 520
>26711
Length = 405
Score = 92.8 bits (229), Expect = 3e-19, Method: Composition-based stats.
Identities = 51/134 (38%), Positives = 75/134 (55%), Gaps = 1/134 (0%)
Frame = -2
Query: 167 IQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAG 226
++Q+L+ + H H GVVH DLKP NLLL+ K +V+L DFGLA ++ Q+ + G
Sbjct: 398 VKQVLDILQHVHAQGVVHMDLKPSNLLLSGD-KLDSVQLIDFGLARKLYPPQETFLNH-G 225
Query: 227 TPGYLSPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFP-S 285
TPG+ SPE L P D+W GV+ YILL G PF + ++ + + F
Sbjct: 224 TPGFTSPEALDVKPISTASDVWGVGVLAYILLSGQSPFQADSATESLKKTQTCDWSFDVC 45
Query: 286 PEWDTVTPEAKDLI 299
P + ++ +AKD I
Sbjct: 44 PSFSNMSQDAKDFI 3
>14126
Length = 1265
Score = 92.0 bits (227), Expect = 6e-19, Method: Compositional matrix adjust.
Identities = 89/304 (29%), Positives = 135/304 (44%), Gaps = 43/304 (14%)
Frame = +3
Query: 62 EEYQLFEELGKGAFSVVRRCVKVLAGQEYAA-KIINTKKLSARDHQKLEREARICRLLK- 119
++Y+ +G GA+ V + + E+ A K I RE + + L+
Sbjct: 189 QKYEEVAVIGNGAYGTVYKARDLRNQGEFVAMKRIRLNNTEEGMPMMAIREISMLKQLEQ 368
Query: 120 --HPNIVRL----HDSISE-EGHHYLIFDLVTGGELFEDIVAREYYSEADA--------S 164
HPN+VRL H++I++ E L+F+ + D+ Y ++ +
Sbjct: 369 YEHPNVVRLLDVSHNTITDREIRLNLVFEYIE-----HDLAT--YLAKCPSPGLGPDRIK 527
Query: 165 HCIQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGF 224
+ Q+L V H +VHRDLKP+NLL++ K +KLADFGLA + A
Sbjct: 528 DLMLQLLNGVDFLHSNRIVHRDLKPQNLLIS---KDGRLKLADFGLA-RIYSFHMALTTV 695
Query: 225 AGTPGYLSPEVLRKDPYGKPVDLWACGVILYIL---------------------LVGYPP 263
T Y SPEVL + YG VD+W+CG I L ++G PP
Sbjct: 696 VVTLWYRSPEVLMQAEYGTSVDIWSCGCIFAELFTRRALFKGSSEFDQLKKIFEVIGLPP 875
Query: 264 F--WDE--DQHR-LYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPSKRITAAEALK 318
W E HR ++ PE D P+AKDL+ KML +RI++ E+L
Sbjct: 876 AGDWPEGVSVHRNSFRPTPPVPLQTLVPEMD---PQAKDLMEKMLVFKSGRRISSRESLL 1046
Query: 319 HPWI 322
HP++
Sbjct: 1047HPYL 1058
>00300
Length = 2318
Score = 89.7 bits (221), Expect = 2e-18, Method: Compositional matrix adjust.
Identities = 71/277 (25%), Positives = 130/277 (46%), Gaps = 10/277 (3%)
Frame = -1
Query: 55 ITCTRFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLER---E 111
I R +Q ++G+G F V V + G+ A K + K D Q+L E
Sbjct: 1679 INVRRVNFRWQRGNKIGEGQFGKVYTAVNMSTGELMALKEM---KFQPNDLQQLREMCDE 1509
Query: 112 ARICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQIL 171
+I ++H N+V+ + + + + G + E A+ E ++I+
Sbjct: 1508 IKIFEGIQHENLVKYYGVEVHKDEMLMFMEYCDTGTIEE--AAKMGLPEYLIRRYTREIV 1335
Query: 172 EAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQA---WFGFAGTP 228
AV H H+ +VHRD+K N+ L S VKL DFG +++++ + GT
Sbjct: 1334 LAVNHLHENSIVHRDIKGANIFLTSN---GHVKLGDFGCSVKLKSHTTMPGEFHNLVGTT 1164
Query: 229 GYLSPEVLRKDP---YGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQI-KAGAYDFP 284
Y++PEV ++ YG+ D+W+ G ++ + G P+ D D + YQ + K G P
Sbjct: 1163 AYMAPEVFTQNDQGGYGRAADIWSLGCVVIEMATGKRPWHDLDNN--YQIMYKVGIGHKP 990
Query: 285 SPEWDTVTPEAKDLINKMLTINPSKRITAAEALKHPW 321
+ D+++ E K ++ ++ +P++R A++ L H +
Sbjct: 989 AVP-DSLSVEGKHFLDLIMCHDPAQRALASQLLDHTF 882
>21433
Length = 590
Score = 74.7 bits (182), Expect(2) = 1e-16, Method: Compositional matrix adjust.
Identities = 48/142 (33%), Positives = 70/142 (49%), Gaps = 5/142 (3%)
Frame = +2
Query: 167 IQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAG 226
I Q+ A+ +CH V+HRD+KPEN +K+ADFG ++ ++ G
Sbjct: 185 IYQLSSALEYCHYRKVIHRDIKPEN---LLLGLKGDLKIADFGWSVHAPSSRRT--TMCG 349
Query: 227 TPGYLSPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSP 286
T YL PE++ + + VDLW+ GV+ Y LVG PP + SP
Sbjct: 350 TLDYLPPEMVEGKTHDENVDLWSLGVLCYEFLVGTPPL---------RPSPTRPPTPASP 502
Query: 287 EWDT-----VTPEAKDLINKML 303
W + VTP A+DLI+K+L
Sbjct: 503 RWTSGSPSIVTPGARDLISKLL 568
Score = 30.0 bits (66), Expect(2) = 1e-16, Method: Compositional matrix adjust.
Identities = 15/47 (31%), Positives = 26/47 (55%)
Frame = +3
Query: 106 QKLEREARICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDI 152
+L RE I L+H NI+R+ ++ YLI + GEL++++
Sbjct: 3 HQLRREIEIQSHLRHDNILRMFGYFHDKTRVYLILEFAPKGELYKEL 143
>13212
Length = 1067
Score = 80.5 bits (197), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 60/173 (34%), Positives = 88/173 (50%), Gaps = 9/173 (5%)
Frame = -1
Query: 159 SEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQ 218
+EA + ++ A+ H+ V+HRD+K N+LL VKLADFG++ + Q
Sbjct: 986 TEAQICYVCHEMCMALDFLHRHHVIHRDIKAGNVLLTI---DGEVKLADFGVSAKNTQTQ 816
Query: 219 QAWFGFAGTPGYLSPEV-----LRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLY 273
Q F GTP +++PEV L+ PY D+W+ GV L PP +++ H +
Sbjct: 815 QKRDTFIGTPYWMAPEVVLCETLKDTPYDFKADIWSLGVTLIEFAQIEPP--NKEMHPMR 642
Query: 274 QQIKAGAYDFPSPE----WDTVTPEAKDLINKMLTINPSKRITAAEALKHPWI 322
IK D P+ E W T KD I K L +P+ R TAAE L+HP++
Sbjct: 641 VLIKIHKSDPPTLEKPKKW---TKLFKDFIAKCLVKDPNLRPTAAELLEHPFM 492
>13066
Length = 551
Score = 76.3 bits (186), Expect = 3e-14, Method: Compositional matrix adjust.
Identities = 53/166 (31%), Positives = 78/166 (46%), Gaps = 5/166 (3%)
Frame = +3
Query: 91 AAKIINTKKLSARDHQKL-EREARICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELF 149
A KII+ +K +K RE + L HP I+++H + +++ G+L
Sbjct: 63 ACKIIDKEKAPVDFVEKFFPRELDLLTKLDHPYIIQIHSILQRXPKNFIFMRFAERGDLL 242
Query: 150 EDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFG 209
I + E A Q+ A+ + H V HRDLK EN+LL+S VKLADFG
Sbjct: 243 TYIQEVGFVKEKQAKIWFYQMTTALNYLHSYDVAHRDLKCENILLSSHFN---VKLADFG 413
Query: 210 LA---IEVEGEQQAWFGFAGTPGYLSPEVLRKDPYG-KPVDLWACG 251
A I GE+ + G+ Y +PE++ PY K D W+ G
Sbjct: 414 FACACITESGEKYMSRTYCGSAAYAAPEIVYGAPYAPKVADAWSLG 551
>09007
Length = 1440
Score = 75.1 bits (183), Expect = 6e-14, Method: Compositional matrix adjust.
Identities = 68/267 (25%), Positives = 120/267 (44%), Gaps = 15/267 (5%)
Frame = -1
Query: 27 GSGAEQQRLSPGPPVPSLTCLPSARMATITCTRFTEE--YQLFEELGKGAFSVVRRCVKV 84
G G + LSP PP ++ SA + + + L + LG+G F VR+ +
Sbjct: 990 GGGEPGRSLSPSPPEHRMSRPVSAVVRPARGKQLISKDCVALSKSLGQGHFGTVRQAIWT 811
Query: 85 LAGQE---YAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGHH-YLIF 140
E A K ++ K+ +D Q+ +E I ++L H NIVR++ + + G L+
Sbjct: 810 AESGEKVQVAVKCLSKDKIH-KDGQEFLKETAIMQMLDHENIVRVYGVVMDNGADIMLVT 634
Query: 141 DLVTGGELFE---DIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASK 197
+L L E ++ AR +S QQ+ + + + +VHRDL N+LL SK
Sbjct: 633 ELAPMRSLLECVKEVSARVDFSVPRLCDFSQQVCDGMSYLESKRLVHRDLAARNILLFSK 454
Query: 198 LKGAAVKLADFGLAIEVEG-----EQQAWFGFAGTPGYLSPEVLRKDPYGKPVDLWACGV 252
K VK++D G++ + + Q + +PE R + D+WA GV
Sbjct: 453 SK---VKISDVGVSGALGAGKEYYQSQQTIHLQNAVAWCAPESFRNLCFSSASDVWAFGV 283
Query: 253 ILYILLV-GYPPFWDEDQHRLYQQIKA 278
+L+ G+ P+ + ++ + + A
Sbjct: 282 LLWEFFTHGFQPWAGLNGQQIMEAVDA 202
>01966
Length = 1735
Score = 71.2 bits (173), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 57/190 (30%), Positives = 86/190 (45%), Gaps = 14/190 (7%)
Frame = -1
Query: 78 VRR---CVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEG 134
VRR C G++ A K I + RE + R L+H NIV L D I E+
Sbjct: 1672 VRRGL*CRHRATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTNIVCLEDVIMEDE 1493
Query: 135 HHYLIFDLVTG-----------GELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVV 183
+L+F+ ++ G + + + + Y + QI+ + CHQ +V
Sbjct: 1492 RLFLVFEFLSMDLKMYIDKFPEGVVLDRRLVKSY---------VFQIVTGINFCHQRRIV 1340
Query: 184 HRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSPEVLRKDPYGK 243
HRDLKP+NLL+ A+K+ADFG+A +A+ T Y +PE+L P
Sbjct: 1339 HRDLKPQNLLINHT---GAIKIADFGMARTFALPVRAYTHEVVTLWYRAPEIL-MGPQST 1172
Query: 244 PVDLWACGVI 253
P W CG +
Sbjct: 1171 P-PXWTCGAL 1145
Score = 32.0 bits (71), Expect = 0.72, Method: Compositional matrix adjust.
Identities = 28/112 (25%), Positives = 49/112 (43%), Gaps = 25/112 (22%)
Frame = -3
Query: 241 YGKPVDLWACGVILYILLVGYPPF-WDEDQHRLYQQI---------------KAGAYDFP 284
Y PVD+W+ G I +L+ P F D + +L++ K A++
Sbjct: 1175 YSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKLPAFNGM 996
Query: 285 SPEW------DTVT---PEAKDLINKMLTINPSKRITAAEALKHPWISHRST 327
P W +T+T DLI + L +P++RI+ + L+H + + T
Sbjct: 995 FPLWKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYFLNVDT 840
>31885
Length = 529
Score = 70.5 bits (171), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 46/152 (30%), Positives = 76/152 (50%), Gaps = 5/152 (3%)
Frame = -2
Query: 118 LKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHC 177
L HP +V L + +E +++ DL GG+L + + E + Q+ + +
Sbjct: 501 LDHPFLVNLWYAFQDEEDLFMVVDLFLGGDLRYHMQQEVSFREDCVKFYLCQLALVLDYL 322
Query: 178 HQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSPEVL- 236
+VHRD+KP+N+LL + + DF +A ++E ++ A +GT Y++PEV
Sbjct: 321 RSQKIVHRDIKPDNILLDEQ---GHCHVTDFNIATQLEDDELA-TSTSGTRPYMAPEVYG 154
Query: 237 ----RKDPYGKPVDLWACGVILYILLVGYPPF 264
+ YG PVD W+ GV L+ LL PF
Sbjct: 153 VAINERRGYGFPVDWWSLGVSLFELLKKRRPF 58
>00392
Length = 668
Score = 69.7 bits (169), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 55/214 (25%), Positives = 104/214 (48%), Gaps = 8/214 (3%)
Frame = +3
Query: 95 INTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGHH-----YLIFDLVTGGELF 149
+ KK + + Q+ + EA + + L+HPNIVR D E H L+ +L+T G L
Sbjct: 33 LQDKKWNKAERQRFKEEAEMLKELQHPNIVRFFDYWEEHNHRNRKVIILVTELMTSGTLK 212
Query: 150 EDIVAREYYSEADASHCIQQILEAV--LHCHQMGVVHRDLKPENLLLASKLKGAAVKLAD 207
+ + + + +Q+L+ + LH V+HRDLK +N+ + +VK+ D
Sbjct: 213 TYLKRFKKPNVKILKNWCRQVLKGLYFLHTRTPPVIHRDLKCDNIFITG--PTGSVKIGD 386
Query: 208 FGLAIEVEGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWD- 266
GLA Q GTP +++PE + ++ Y + VD++A G+ + + P+ +
Sbjct: 387 LGLA--TLKNQSFAKSVIGTPEFMAPE-MYEEHYDEAVDVYAFGMCMLEMASSEYPYSEC 557
Query: 267 EDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLIN 300
+ ++Y+++ +G P E +D+I+
Sbjct: 558 SNAAQIYKRVTSGV--LPEALDKVAITEIRDIIH 653
>28638
Length = 1458
Score = 63.9 bits (154), Expect(2) = 3e-12, Method: Compositional matrix adjust.
Identities = 37/99 (37%), Positives = 57/99 (57%), Gaps = 2/99 (2%)
Frame = -1
Query: 168 QQILEAVLHCH--QMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFA 225
QQ+ A+L +M ++H DLKPEN+LL + K +A+K+ DFG + ++ Q + +
Sbjct: 816 QQLCTALLFLATPEMNIIHCDLKPENILLCNP-KRSAIKIVDFGSSCQLG---QRIYQYI 649
Query: 226 GTPGYLSPEVLRKDPYGKPVDLWACGVILYILLVGYPPF 264
+ Y SPEVL PY +D+W+ G IL + G PP
Sbjct: 648 QSRFYRSPEVLLGVPYDLAIDMWSLGCILVEMHTGEPPL 532
Score = 25.4 bits (54), Expect(2) = 3e-12, Method: Compositional matrix adjust.
Identities = 22/92 (23%), Positives = 42/92 (45%), Gaps = 6/92 (6%)
Frame = -3
Query: 59 RFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLL 118
++ + Y++ +GKG+F V + ++ A KII KK + + E ++ L+
Sbjct: 1156 KWLDRYEIDSLIGKGSFGQVVKAYDHGDQEQVAIKIIKNKKPFL---NQAQIEVKLLELM 986
Query: 119 KHPN------IVRLHDSISEEGHHYLIFDLVT 144
+ IVRL H L+F+L++
Sbjct: 985 NRHDADNXYYIVRLKRHFMFRNHLCLVFELLS 890
>00486
Length = 797
Score = 68.2 bits (165), Expect = 7e-12, Method: Compositional matrix adjust.
Identities = 35/102 (34%), Positives = 56/102 (54%)
Frame = -2
Query: 224 FAGTPGYLSPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDF 283
F GT Y++PE+L + +GK VD W+ G ++Y +L G PPF E++ + +I G +
Sbjct: 778 FCGTIEYMAPEILTRTGHGKAVDWWSLGALMYDMLTGSPPFTAENRKKTIDKILKGKLNL 599
Query: 284 PSPEWDTVTPEAKDLINKMLTINPSKRITAAEALKHPWISHR 325
P +T EA+ LI K+L NP++R+ P H+
Sbjct: 598 PP----YLTNEARGLIKKLLRKNPAERLGGGHDDSGPIKDHQ 485
>01718
Length = 959
Score = 68.2 bits (165), Expect = 8e-12, Method: Compositional matrix adjust.
Identities = 60/219 (27%), Positives = 107/219 (48%), Gaps = 5/219 (2%)
Frame = +3
Query: 41 VPSLTCLPSARMATITCTRFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKL 100
+P +C + R A TR + + E++G G FS V + + GQ A K+ NT +
Sbjct: 93 LPKSSC-QALRHAVSALTRLDDF--ICEKIGAGFFSEVFKVTHRITGQVMALKM-NT--M 254
Query: 101 SARDHQKLEREARICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSE 160
++ H L RE ++ L+H NI+R EG + + + + G L + + ++ E
Sbjct: 255 TSNRHNML-REVQLLNRLQHANILRFMGVCVHEGQLHALTEYIPSGNLEQLLEKKD--EE 425
Query: 161 ADASHCIQQIL---EAVLHCHQMGVVHRDLKPENLLLASKLK-GAAVKLADFGLAIEV-E 215
+ IQ L + + H +HRDL +N+L+ + G +ADFGLA ++ +
Sbjct: 426 LPWTQRIQLTLGLARGLDYLHSTRFIHRDLTSKNILIRREDNHGYHAVIADFGLATKIPD 605
Query: 216 GEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDLWACGVIL 254
+ G+P +++PEVL Y + DL++ G+I+
Sbjct: 606 PLDKEKLPTVGSPYWMAPEVLNGHFYNERADLFSVGIIM 722
>27405
Length = 532
Score = 67.4 bits (163), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 49/170 (28%), Positives = 79/170 (46%), Gaps = 5/170 (2%)
Frame = -3
Query: 74 AFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLL-----KHPNIVRLHD 128
F V C K G+ YA K ++ K++ + + L RI L P IV +
Sbjct: 530 GFGEVYGCRKADTGKMYAMKCLDKKRIKMKGGETLALNERIMLSLVSTGEGSPFIVCMTY 351
Query: 129 SISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLK 188
+ I DL+ GG+L + ++E + +++ + H H VV+RDLK
Sbjct: 350 AFQTPEKLCFILDLMNGGDLHYHLSQHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLK 171
Query: 189 PENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSPEVLRK 238
P N+LL + V+++D GLA + ++ GT GY++PEVL K
Sbjct: 170 PANILLD---ENGHVRISDLGLACDF--SKKKPHASVGTHGYMAPEVLMK 36
>19761
Length = 473
Score = 67.4 bits (163), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 44/130 (33%), Positives = 65/130 (50%)
Frame = -3
Query: 175 LHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSPE 234
+H H ++HRDLKP+N+ + K V+L D GLA ++ G GT YLSPE
Sbjct: 375 MHTHTPVILHRDLKPQNIYVTEK---GDVRLGDLGLARKLTGPADFATSQVGTIMYLSPE 205
Query: 235 VLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPE 294
+L + PY D+W+ G + Y + G + L Q+ G P P D + E
Sbjct: 204 ILSQQPYNSKSDIWSLGCVFYD-ITGKKGSDEMGVMFLLVQVMGGR-KLPLP--DHYSQE 37
Query: 295 AKDLINKMLT 304
+D I++MLT
Sbjct: 36 FRDTISRMLT 7
>38560
Length = 479
Score = 65.9 bits (159), Expect = 4e-11, Method: Compositional matrix adjust.
Identities = 44/121 (36%), Positives = 61/121 (50%), Gaps = 5/121 (4%)
Frame = -3
Query: 226 GTPGYLSPEVLRKDPY-GKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFP 284
G+P Y +PE++ Y G D+W+ GV+LY LL GY PF DE L Q+ + +
Sbjct: 399 GSPAYAAPELISGLEYLGSEADIWSMGVLLYALLCGYLPFDDEKXSHL*QKNQKRKDEV- 223
Query: 285 SPEWDTVTPEAKDLINKMLTINPSKRITAAEALKHPWISHRSTV----ASCMHRQETVDC 340
PEW ++ + L+ ML +PS RIT L H W++ V AS R DC
Sbjct: 222 -PEW--LSEDTTKLLEGMLQTDPSHRITIRRLLDHHWLNQGFNVPVEWASKYKRTLDEDC 52
Query: 341 L 341
L
Sbjct: 51 L 49
>06405
Length = 1965
Score = 64.7 bits (156), Expect = 8e-11, Method: Compositional matrix adjust.
Identities = 56/221 (25%), Positives = 95/221 (42%), Gaps = 4/221 (1%)
Frame = +1
Query: 63 EYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPN 122
E + LG G + V + + A K + ++ D EA I + +KHPN
Sbjct: 262 EIAMKHRLGGGQYGDVYEAMWKRYNKIVAVKTLKEDTMALND---FLEEAAIMKEMKHPN 432
Query: 123 IVRLHDSISEEGHHYLIFDLVTGGELFEDIVA--REYYSEADASHCIQQILEAVLHCHQM 180
+V+L + E Y++ + + G L + + + RE + QI + +
Sbjct: 433 LVQLLGVCTREPPFYIVTEFMPHGNLLDYLRSSTREENGPTALMYMATQIASGMAYLETK 612
Query: 181 GVVHRDLKPENLLLASKLKGAAVKLADFGLA-IEVEGEQQAWFGFAGTPGYLSPEVLRKD 239
+HRDL N L+A VK+ADFGLA + + A G + +PE L +
Sbjct: 613 NFIHRDLAARNCLVAD---SNMVKVADFGLARLMKDDTYTAHIGAKFPIKWTAPEGLAFN 783
Query: 240 PYGKPVDLWACGVILYILLV-GYPPFWDEDQHRLYQQIKAG 279
+ D+WA GV+L+ L G P+ + +Y ++ G
Sbjct: 784 RFSTRSDIWAFGVLLWELATYGMSPYPGVELTEVYHLLERG 906
>18921
Length = 697
Score = 64.7 bits (156), Expect = 9e-11, Method: Compositional matrix adjust.
Identities = 47/201 (23%), Positives = 95/201 (47%), Gaps = 1/201 (0%)
Frame = +2
Query: 64 YQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNI 123
+ + +LG+G++ V + + GQ A K + D Q++ +E I + I
Sbjct: 35 FDILGKLGEGSYGSVFKSLHKETGQVLAIKQVPVDT----DLQEIIKEISIMQQCDSKYI 202
Query: 124 VRLHDSISEEGHHYLIFDLVTGGELFEDIVAR-EYYSEADASHCIQQILEAVLHCHQMGV 182
V+ + S + +++ + G + + + R + E + + + L+ + + H
Sbjct: 203 VKYYGSYFKNTDLWIVMEYCGAGSVSDIMRLRNKTLVEREIATILYYTLKGLXYLHSRRK 382
Query: 183 VHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSPEVLRKDPYG 242
+HRD+K N+LL ++ KLADFG+A ++ GTP +++PEV+++ Y
Sbjct: 383 IHRDIKAGNILLNNE---GHAKLADFGVAGQLTDTMAKRNTVIGTPYWMAPEVIQEIGYD 553
Query: 243 KPVDLWACGVILYILLVGYPP 263
D+W+ G+ + G PP
Sbjct: 554 CVADIWSLGITALEMAEGKPP 616
>21808
Length = 1011
Score = 63.5 bits (153), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 51/195 (26%), Positives = 91/195 (46%), Gaps = 3/195 (1%)
Frame = +1
Query: 95 INTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVA 154
I T K D + EA+I + L+HP +++L+ +++ ++I +L+ G L E +
Sbjct: 34 IKTLKSGTMDPKDFLAEAQIMKKLRHPKLIQLYAVCTQDDPIFIITELMKNGSLLEFLQG 213
Query: 155 REYYSEADASHCI-QQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIE 213
+ + A I QI + + +HRDL N+L++ VK+ADFGLA
Sbjct: 214 KGRVLKLPALIDIGAQIACGMAYLESQNYIHRDLAARNILVSDN---NTVKIADFGLARV 384
Query: 214 V-EGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDLWACGVILY-ILLVGYPPFWDEDQHR 271
+ E E +A G + +PE + + D+W+ G++L + G P+
Sbjct: 385 IKEDEYEARVGARFPIKWTAPEAANYNRFTIKSDVWSFGILLTETVTYGRVPYPGMTNAE 564
Query: 272 LYQQIKAGAYDFPSP 286
+ Q++ G Y P P
Sbjct: 565 VLHQVEHG-YRMPCP 606
>26560
Length = 398
Score = 63.5 bits (153), Expect = 2e-10, Method: Composition-based stats.
Identities = 38/113 (33%), Positives = 61/113 (53%), Gaps = 1/113 (0%)
Frame = -1
Query: 158 YSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGE 217
++E + +++ + H H VV+RDLKP N+LL + V+++D GLA + +
Sbjct: 365 FTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLD---ENGHVRISDLGLACDFSKK 195
Query: 218 QQAWFGFAGTPGYLSPEVLRK-DPYGKPVDLWACGVILYILLVGYPPFWDEDQ 269
+ GT GY++PEVL K Y D ++ G +LY LL G+ PF +Q
Sbjct: 194 RP--HASVGTHGYMAPEVLMKGQSYDSSADWFSFGCMLYKLLKGHSPFRQHNQ 42
>29581
Length = 1278
Score = 63.5 bits (153), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 65/243 (26%), Positives = 106/243 (43%), Gaps = 35/243 (14%)
Frame = -2
Query: 118 LKHPNIVRLHDSISEEGHHYLIF-------DLVTGGELFEDIVAREYYSEADASHCIQQI 170
L+H NIV+L + + + L DL + L +++ A +SE+ + Q+
Sbjct: 1184 LRHQNIVQLQEVVVGKSLDSLFLVMEYCEQDLAS---LLDNMPAP--FSESQVKCIVLQL 1020
Query: 171 LEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGY 230
L+ + + H+ ++HRDLK NLL+ K VK+ADFGLA Q+ T Y
Sbjct: 1019 LKGLRYLHEAFIIHRDLKVSNLLMTDK---GCVKIADFGLARNYGKPQKPMTPKVVTLWY 849
Query: 231 LSPEVL-RKDPYGKPVDLWACGVILYILLVGYPPFW----DEDQHRLYQQ--------IK 277
+PE+L + +D+W+ G IL LL G+ P D Q L + I
Sbjct: 848 RAPELLFGSKTHSTAIDMWSAGCILGELL-GHKPLMPGRSDLQQIELIMELLGTPNDTIW 672
Query: 278 AGAYDFPSPEWDTVTPEAKD---------------LINKMLTINPSKRITAAEALKHPWI 322
G P+ E T+ + + L+N + +P KR TA + L+H +
Sbjct: 671 PGFSQLPAFEQFTLKKQPYNNLRHTFPWLSESGIRLLNGLFMYHPQKRATAEDCLEHSYF 492
Query: 323 SHR 325
+
Sbjct: 491 KEQ 483
>21418
Length = 831
Score = 62.4 bits (150), Expect = 4e-10, Method: Compositional matrix adjust.
Identities = 25/57 (43%), Positives = 38/57 (66%)
Frame = +2
Query: 272 LYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPSKRITAAEALKHPWISHRSTV 328
+ ++I++G YDFP PEW V+ AKDLI ML ++PSKR+ + L++ WI+ V
Sbjct: 2 MKKRIRSGQYDFPDPEWTNVSQAAKDLIKGMLNVDPSKRLCIEDVLRNKWIAQYDAV 172
>36002
Length = 253
Score = 61.2 bits (147), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 26/56 (46%), Positives = 36/56 (64%)
Frame = +1
Query: 269 QHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPSKRITAAEALKHPWISH 324
Q L+ +I+ G Y FPS EW ++ AKDLI +L P KR +AA+ LKHPW+ +
Sbjct: 49 QELLFNRIQDGNYFFPSMEWSAISSSAKDLIRHLLVREPRKRYSAADVLKHPWVCN 216
>20152
Length = 445
Score = 60.8 bits (146), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 34/92 (36%), Positives = 48/92 (52%), Gaps = 1/92 (1%)
Frame = +1
Query: 233 PEVLRKDPYGKP-VDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTV 291
PE+L D Y P VD+W+ GVILY+L+VG PF + + I Y P +
Sbjct: 1 PEILLGDSYDAPAVDVWSLGVILYMLVVGEAPFQEANDSETLTMIMDCRYQIPP----HI 168
Query: 292 TPEAKDLINKMLTINPSKRITAAEALKHPWIS 323
+ + +DLI KML P R + L HPW++
Sbjct: 169 SHKCQDLIEKMLQREPVDRASLPHILAHPWLN 264
>12786
Length = 460
Score = 60.5 bits (145), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 38/119 (31%), Positives = 57/119 (47%), Gaps = 22/119 (18%)
Frame = -3
Query: 168 QQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWF--GFA 225
+++L AV H GV+H DLKP N +L + +KL DFG+A ++ ++ +
Sbjct: 389 REMLRAVKALHNEGVIHSDLKPANFMLVA----GNLKLIDFGIANTLQQDKTSVLKDSRV 222
Query: 226 GTPGYLSPEVL-----------------RKDP---YGKPVDLWACGVILYILLVGYPPF 264
GTP Y+SPE + R P G D+W+ G ILY ++ G PF
Sbjct: 221 GTPSYMSPEAIMAACDDSADDSMEEDGHRTKPKYKVGVRSDVWSLGCILYNMVYGRTPF 45
>29590
Length = 320
Score = 45.1 bits (105), Expect(2) = 2e-09, Method: Composition-based stats.
Identities = 17/39 (43%), Positives = 25/39 (64%)
Frame = +3
Query: 226 GTPGYLSPEVLRKDPYGKPVDLWACGVILYILLVGYPPF 264
GTP Y++PEVL +P D+W+ GV+ Y++L PF
Sbjct: 60 GTPDYVAPEVLDYEPLSIQTDMWSLGVLSYVMLTACSPF 176
Score = 35.0 bits (79), Expect(2) = 2e-09, Method: Composition-based stats.
Identities = 15/46 (32%), Positives = 24/46 (52%)
Frame = +2
Query: 267 EDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPSKRIT 312
++Q + I DFP + ++P AKD I K+L +P R+T
Sbjct: 182 DNQQETFCNISQVKLDFPDDLFSHISPHAKDFIKKLLVKDPRHRMT 319
>04591
Length = 1117
Score = 59.3 bits (142), Expect = 4e-09, Method: Compositional matrix adjust.
Identities = 48/157 (30%), Positives = 77/157 (49%), Gaps = 12/157 (7%)
Frame = -2
Query: 110 REARICRLLKHPNIVRLHDSI-SEEGHH-------YLIF---DLVTGGELFEDIVAREYY 158
RE +I + L+H N+V+L + ++ G + YLIF D G L R +
Sbjct: 1074 REIKILQQLEHENVVQLQEICHTQAGPYNRYKSTFYLIFEYCDYDLAGLLNN---LRVKF 904
Query: 159 SEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQ 218
S AD + + Q+L + + H ++HRD+K N+LL + +KLADFGL+ +
Sbjct: 903 SLADKKNLMSQLLNGLFYIHTKQILHRDIKAANILLT---RDGVLKLADFGLS-RPWVKS 736
Query: 219 QAWFGFAGTPGYLSPEVLRKD-PYGKPVDLWACGVIL 254
+ T Y PE+L + YG +D+W G I+
Sbjct: 735 KRLTNRVVTLWYRPPELLLGEREYGPEIDMWGVGCIM 625
>01756
Length = 1858
Score = 58.9 bits (141), Expect = 4e-09, Method: Compositional matrix adjust.
Identities = 56/214 (26%), Positives = 95/214 (44%), Gaps = 22/214 (10%)
Frame = -3
Query: 63 EYQLFEELGKGAFSVV--RRCVKVLAGQEYAAKIINTKKLSARDHQK-----LEREARIC 115
+Y+ ++G+G F V RC K +++ KK+ + ++ RE +I
Sbjct: 1739 KYEKLAKIGQGTFGEVFKARCKK-------TKQVVAMKKVLMDNEKEGFPITALREIKIL 1581
Query: 116 RLLKHPNIVRLHDSISEEG--------HHYLIFDLV---TGGELFEDIVAREYYSEADAS 164
+LL H N+V L + S + YL+F+ G L V ++ +
Sbjct: 1580 QLLNHENVVDLIEICSTKATSANRYKSMFYLVFEFCEHDLAGLLSNMSVV---FNLPEIK 1410
Query: 165 HCIQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGL--AIEVEGEQ-QAW 221
++Q++ + + H+ ++HRD+K N+L+ K +KLADFGL A V Q +
Sbjct: 1409 EVMKQLMNGLYYIHRNKILHRDMKAANILIT---KQGVLKLADFGLARAFSVNLRQPNRY 1239
Query: 222 FGFAGTPGYLSPEVLRKD-PYGKPVDLWACGVIL 254
T Y PE+L D Y +D W G I+
Sbjct: 1238 TNRVVTLWYRPPELLLGDRNYSTAIDQWGAGCIM 1137
>19094
Length = 898
Score = 50.4 bits (119), Expect(2) = 5e-09, Method: Compositional matrix adjust.
Identities = 27/93 (29%), Positives = 50/93 (53%)
Frame = +1
Query: 160 EADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQ 219
E + + + L+ + + H +HRD+K N+LL ++ KLADFG+A ++
Sbjct: 55 EREIATILYYTLKGL*YLHSRRKIHRDIKAGNILLNNE---GHAKLADFGVAGQLTDTMA 225
Query: 220 AWFGFAGTPGYLSPEVLRKDPYGKPVDLWACGV 252
GTP +++PEV+++ Y D+W+ G+
Sbjct: 226 KRNTVIGTPYWMAPEVIQEIGYDCVADIWSLGI 324
Score = 28.5 bits (62), Expect(2) = 5e-09, Method: Compositional matrix adjust.
Identities = 21/66 (31%), Positives = 29/66 (43%), Gaps = 3/66 (4%)
Frame = +3
Query: 260 GYPPFWDEDQHRLYQQIKAGAYDFPSPEW---DTVTPEAKDLINKMLTINPSKRITAAEA 316
G PP+ D R I P P + D + E D ++K L NP R TA +
Sbjct: 345 GKPPYGDIHPMRAIFMIPTK----PPPSFRQPDKWSTEFIDFVSKCLVKNPENRATAVDL 512
Query: 317 LKHPWI 322
L+H +I
Sbjct: 513 LQHDFI 530
>27546
Length = 426
Score = 56.2 bits (134), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 38/103 (36%), Positives = 53/103 (51%), Gaps = 1/103 (0%)
Frame = -1
Query: 110 REARICRLLKHPNIVRLHDSISEEGHHYLIF-DLVTGGELFEDIVAREYYSEADASHCIQ 168
RE I L HPNI+++H SI + G IF G++ I EA
Sbjct: 333 RELEILTRLDHPNIIQIH-SILQRGPKIFIFMRYAEKGDMLSHIKKTGPIDEAQTKVWFF 157
Query: 169 QILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLA 211
Q+ +A+ + H + HRDLK EN+LL+ +L VK+ADFG A
Sbjct: 156 QMAKALQYLHSHDIAHRDLKCENILLSKRLN---VKIADFGFA 37
>11185
Length = 473
Score = 55.5 bits (132), Expect = 5e-08, Method: Compositional matrix adjust.
Identities = 45/167 (26%), Positives = 75/167 (44%), Gaps = 23/167 (13%)
Frame = +1
Query: 176 HCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGE--QQAWFGFA-------- 225
+ H +G++ DL+P +LL + +K ADFGL+ +VEGE ++ +F FA
Sbjct: 46 YIHSLGILFHDLRPSKVLLDTS---GVLKFADFGLS-KVEGENLEELFFKFAEAGDQWNI 213
Query: 226 -------------GTPGYLSPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRL 272
G+P Y++PEV + DLWA G + Y + G RL
Sbjct: 214 QSAEEMMKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSG---------SRL 366
Query: 273 YQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPSKRITAAEALKH 319
+ PSPE+ +L+ +L + ++R++ A +KH
Sbjct: 367 SAK--------PSPEF-------LNLLESLLQKDSTRRLSWASLVKH 462
>18663
Length = 600
Score = 55.5 bits (132), Expect = 5e-08, Method: Compositional matrix adjust.
Identities = 34/97 (35%), Positives = 51/97 (52%), Gaps = 9/97 (9%)
Frame = +2
Query: 224 FAGTPGYLSPEVLRKDPYGKPVDLWACGVILYILLVGYPPF------WDEDQHR---LYQ 274
F GTP Y++PE+LR + YG VD WA GV+LY +L G PF + DQ+ L+Q
Sbjct: 8 FCGTPNYIAPEILRGEDYGFSVDWWALGVLLYEMLAGRSPFDIAGASENPDQNTEDYLFQ 187
Query: 275 QIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPSKRI 311
I P +++ +A ++ L NP+ R+
Sbjct: 188 VILEKTIRIPR----SLSVKAASVLKGFLNKNPADRL 286
>04138
Length = 800
Score = 55.5 bits (132), Expect = 6e-08, Method: Compositional matrix adjust.
Identities = 55/182 (30%), Positives = 77/182 (42%), Gaps = 34/182 (18%)
Frame = +1
Query: 172 EAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGL--AIEVEGEQ-QAWFGFAGTP 228
E + + H+ ++HRD+K N+L+ K +KLADFGL A V Q + T
Sbjct: 46 ERLYYIHRNKILHRDMKAANILIT---KQGVLKLADFGLARAFSVNLRQPNRYTNRVVTL 216
Query: 229 GYLSPEVLRKD-PYGKPVDLWACGVI---------------------LYILLVG--YPPF 264
Y PE+L D Y +D W G I L L G P
Sbjct: 217 WYRPPELLLGDRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQNQLTLITQLCGSITPEV 396
Query: 265 W-DEDQHRLYQQIK----AGAYDFPSPEWDTVT--PEAKDLINKMLTINPSKRITAAEAL 317
W Q +Y QIK AG + + + P DL ++L ++PS+RI+A EAL
Sbjct: 397 WPGVTQLSMYHQIKGALAAGRKNIIRDRFARILKDPYGLDLFERLLKMDPSQRISADEAL 576
Query: 318 KH 319
H
Sbjct: 577 NH 582
>27274
Length = 396
Score = 55.1 bits (131), Expect = 7e-08, Method: Compositional matrix adjust.
Identities = 29/98 (29%), Positives = 52/98 (53%), Gaps = 8/98 (8%)
Frame = -1
Query: 234 EVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHR--------LYQQIKAGAYDFPS 285
E+LR +G VD+W+ G++L+ LL G+ PF E R +Y QI G+
Sbjct: 375 ELLRGQQHGPTVDMWSLGILLHELLSGHVPFEPERGSRQMARNMMAVYAQIIRGS-SRDV 199
Query: 286 PEWDTVTPEAKDLINKMLTINPSKRITAAEALKHPWIS 323
+ ++ D + +++ + +KR+T+ +A HPWI+
Sbjct: 198 CDGLALSTHGADFLRRLVQLEDTKRLTSQQAFSHPWIA 85
>20655
Length = 1181
Score = 55.1 bits (131), Expect = 7e-08, Method: Compositional matrix adjust.
Identities = 21/57 (36%), Positives = 35/57 (61%)
Frame = +2
Query: 272 LYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPSKRITAAEALKHPWISHRSTV 328
+ ++I+ G Y+FP PEW V+ +AKDLI ML +P KR+ + + W++ + V
Sbjct: 2 MKKRIRNGQYEFPKPEWSRVSQDAKDLIRGMLCTDPDKRLNIKQVMASKWVADNTMV 172
>31120
Length = 439
Score = 52.8 bits (125), Expect = 3e-07, Method: Composition-based stats.
Identities = 30/90 (33%), Positives = 47/90 (52%), Gaps = 1/90 (1%)
Frame = +1
Query: 234 EVLRKDPYG-KPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVT 292
EV+ PY K D W+ GVIL+I+L G PF D + ++L + ++ Y F D V+
Sbjct: 1 EVVCGVPYDPKMADAWSLGVILFIMLNGKMPFDDSNLNKLLEDQRSKKYSFRRKLQDLVS 180
Query: 293 PEAKDLINKMLTINPSKRITAAEALKHPWI 322
P A+ ++ +L N + R E L W+
Sbjct: 181 PNARSTVSVLLEPNSAMRWDLNEVLNCQWL 270
>02638
Length = 1490
Score = 52.4 bits (124), Expect = 5e-07, Method: Compositional matrix adjust.
Identities = 29/102 (28%), Positives = 52/102 (50%), Gaps = 1/102 (0%)
Frame = +1
Query: 226 GTPGYLSPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDED-QHRLYQQIKAGAYDFP 284
GT +++PEVLR + YG+ D+W+ G ++ + PP+ D + L K + P
Sbjct: 22 GTIAFMAPEVLRGESYGRACDVWSVGCVMIEMCTCRPPWNSHDISNHLALIFKIASSVDP 201
Query: 285 SPEWDTVTPEAKDLINKMLTINPSKRITAAEALKHPWISHRS 326
P + ++P +DL+ + L + R +A + L HP + S
Sbjct: 202 PPIPENMSPPVRDLMLRCLEQDSDFRPSAKDLLMHPLFTKYS 327
>17300
Length = 480
Score = 52.0 bits (123), Expect = 7e-07, Method: Compositional matrix adjust.
Identities = 33/113 (29%), Positives = 56/113 (49%), Gaps = 7/113 (6%)
Frame = +1
Query: 179 QMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPG------YLS 232
MG VHRDL N+L+ L K+ADFGL+ E+E + G T G + +
Sbjct: 28 DMGYVHRDLAARNILVNEIL---VCKVADFGLSREIESDTTE--GAYTTKGGKIPVRWTA 192
Query: 233 PEVLRKDPYGKPVDLWACGVILY-ILLVGYPPFWDEDQHRLYQQIKAGAYDFP 284
PE + + D+W+ GV+++ ++ G P+W+ + + ++ G Y P
Sbjct: 193 PEAIAYRKFTSASDVWSFGVVMWEVMSYGERPYWNWSNQDVIKAVEKG-YRLP 348
>32000
Length = 644
Score = 51.6 bits (122), Expect = 7e-07, Method: Compositional matrix adjust.
Identities = 44/148 (29%), Positives = 74/148 (50%), Gaps = 25/148 (16%)
Frame = -1
Query: 201 AAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSPEVLRK-DPYGKPVDLWACGVILYILLV 259
A +K+ADFGLA + + T Y +PE+L Y PVD+W+ G I ++
Sbjct: 578 AKMKIADFGLARVFGLPVRTYTHEVITLWYRAPEILLGCRFYSVPVDIWSLGCIFVEMMT 399
Query: 260 G---YPPFWDEDQ-HRLY-------QQIKAGAYDFPS-----PEW-----DTVTPEAK-- 296
+P + DQ +R++ +++ G P P+W +TV +K
Sbjct: 398 RRALFPGDSEIDQLYRIFRTLGTPDEKVWPGVSKLPDYKPTFPKWPLKNLETVVSLSKVG 219
Query: 297 -DLINKMLTINPSKRITAAEALKHPWIS 323
DL+ +MLT NP++RI+A A++HP+ +
Sbjct: 218 LDLLKRMLTYNPNRRISARSAMRHPYFN 135
>04852
Length = 1462
Score = 51.2 bits (121), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 50/218 (22%), Positives = 92/218 (42%), Gaps = 30/218 (13%)
Frame = +1
Query: 100 LSARDHQKLEREARICRLLK----HPNIVRLHDSISEEGHHYLIFDLVTGGEL------- 148
++A + Q +E ++ + +K H NIV ++ G ++I + G L
Sbjct: 55 VTAVEEQDFVQELQVMKAVKKMGSHINIVNFLGCCTQGGPLWVIVEFAKNGNLRDFLESC 234
Query: 149 ------FEDIVARE---YYSEADASHCIQ---------QILEAVLHCHQMGVVHRDLKPE 190
+ V+ + +Y++ H I+ QI + +HRDL
Sbjct: 235 RDGINGYGKFVSPQDPGWYTKTPGGHVIRRKNLLSYAFQIARGMEFLASRKCIHRDLAAR 414
Query: 191 NLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDLWAC 250
N+L+ + +K+ADFGL+ + ++ G +++PE L Y D+W+
Sbjct: 415 NVLVTEE---HVLKIADFGLSRTGDYYKKRSGGRLPVK-WMAPEALFDMRYTTKSDVWSF 582
Query: 251 GVILY-ILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPE 287
GV+L+ I +G P+ LY ++ AY P PE
Sbjct: 583 GVVLWEIFSLGGMPYASIPNEELYSKLLDDAYRMPRPE 696
>19301
Length = 712
Score = 51.2 bits (121), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 41/143 (28%), Positives = 64/143 (44%)
Frame = +2
Query: 67 FEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRL 126
E LG GA V + L +E A K + K E + R R L HPNI+
Sbjct: 320 LEWLGSGAQGAV--FLGKLCAEEVAVKKVRDIK---------ETDIRNLRKLNHPNIISF 466
Query: 127 HDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRD 186
++ + +I + G+L+E + + A +QI + + H ++HRD
Sbjct: 467 KGVCTQAPCYCIIMEYCPYGQLYEVLRDGKEIPPALVLDWSKQIASGMNYLHSHKIIHRD 646
Query: 187 LKPENLLLASKLKGAAVKLADFG 209
LK N+L+A K VK++DFG
Sbjct: 647 LKSPNVLVA---KNDVVKISDFG 706
>03508
Length = 1463
Score = 50.4 bits (119), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 44/198 (22%), Positives = 90/198 (45%), Gaps = 5/198 (2%)
Frame = +1
Query: 62 EEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLKHP 121
++YQ+ +LG+G +S V + V + K + + + + L
Sbjct: 589 DDYQIVRKLGRGKYSEVFEAINVTNNE----KCVIKILKPVKKKKIKREIKILENLRGGT 756
Query: 122 NIVRL----HDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHC 177
N++ L D +S LIF+ V + + + +++ D + ++++A+ C
Sbjct: 757 NVITLLAIVKDPVSRTPA--LIFEHVNNTDFKQ---LYQTFTDYDIRFYLYELMKALDFC 921
Query: 178 HQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSPEVLR 237
H MG++HRD+KP N+++ + K ++L D+GLA E + + + PE+L
Sbjct: 922 HSMGIMHRDVKPHNVMIDHENK--KLRLIDWGLA-EFYHPGMEYNVRVASRYFKGPELLL 1092
Query: 238 K-DPYGKPVDLWACGVIL 254
Y +D+W+ G +
Sbjct: 1093DYQMYDYSLDMWSLGCMF 1146
Score = 37.0 bits (84), Expect = 0.021, Method: Compositional matrix adjust.
Identities = 13/32 (40%), Positives = 24/32 (75%)
Frame = +2
Query: 291 VTPEAKDLINKMLTINPSKRITAAEALKHPWI 322
++PEA D ++K+L + ++R+TA EA+ HP+
Sbjct: 1358 ISPEALDFLDKLLRYDHNERLTAREAMDHPYF 1453
>17722
Length = 680
Score = 48.9 bits (115), Expect = 5e-06, Method: Compositional matrix adjust.
Identities = 24/72 (33%), Positives = 40/72 (55%)
Frame = -3
Query: 245 VDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLT 304
VD W GV++Y ++ G PF++ D L++ I FP ++ EAK L++ +L
Sbjct: 678 VDWWGTGVVMYEMMCGRLPFYNRDHDVLFELILLQNVKFPR----NLSEEAKTLLSGLLA 511
Query: 305 INPSKRITAAEA 316
NP +R+ +EA
Sbjct: 510 KNPKRRLGGSEA 475
>28157
Length = 400
Score = 48.9 bits (115), Expect = 5e-06, Method: Compositional matrix adjust.
Identities = 38/133 (28%), Positives = 67/133 (50%), Gaps = 6/133 (4%)
Frame = +3
Query: 88 QEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGE 147
++ A K I +++ Q+L++ +R+ HPNIV L+ + + L+ + GG
Sbjct: 3 KDVAVKRIESEQEKKSFMQELKQLSRV----SHPNIVCLYGACRDHPV-CLVMEYAEGGS 167
Query: 148 LFEDIVAREYYSEADASHCIQQILEAVL---HCHQM---GVVHRDLKPENLLLASKLKGA 201
L+ + + A+H + +L+ L + H M ++HRDLKP NLLL G
Sbjct: 168 LYNVLHGSGPQPQYTAAHAMNWLLQCALGVEYLHGMKPKALIHRDLKPPNLLLIQ--CGT 341
Query: 202 AVKLADFGLAIEV 214
+K+ DFG A ++
Sbjct: 342 KLKICDFGTACDI 380
>14116
Length = 1017
Score = 48.9 bits (115), Expect = 5e-06, Method: Compositional matrix adjust.
Identities = 50/202 (24%), Positives = 88/202 (43%), Gaps = 11/202 (5%)
Frame = -1
Query: 68 EELGKGAFSVVRRCVKVLAGQE----YAAKIINTKKLSARDHQKLEREARICRLLKHPNI 123
EE+GKG F V+R L Q+ A K ++ + Q +EA I + H N+
Sbjct: 618 EEIGKGNFGCVKRGFLTLPEQKGDILVAVKTLHNNNPREIELQSFLQEALIMKDFHHSNV 439
Query: 124 VRLHD-SISEEGHHYLIFDLVTGGELFEDIVAREYY-SEADASHCIQQILEAVLHCHQMG 181
+ L ++ + ++ + G+L I ++ + D I + + +
Sbjct: 438 LTLIGICLNLDDMPLVVLPFMKHGDLLTYIRDDQHQPTIKDLIMYGVDIARGMDYLAGLK 259
Query: 182 VVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPG-----YLSPEVL 236
VHRDL N +L VK+ADFGLA ++ ++ ++ +++ E L
Sbjct: 258 FVHRDLAARNCMLDEDFH---VKVADFGLARDIY--EKEYYSSENKKAKLPVKWMALESL 94
Query: 237 RKDPYGKPVDLWACGVILYILL 258
K Y D+W+ GV+L+ LL
Sbjct: 93 EKGNYDSKTDVWSYGVVLWELL 28
>00715
Length = 1788
Score = 47.4 bits (111), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 50/199 (25%), Positives = 85/199 (42%), Gaps = 30/199 (15%)
Frame = +1
Query: 118 LKHPNIVRLHDSIS----EEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQ---QI 170
L+H N+V + + S E+G +L + V G L + ++ + D+S + Q+
Sbjct: 97 LRHVNVVSILGATSLHRFEDGA-WLAMEYV--GPLNLQTILNDHQQDIDSSMRLSLALQM 267
Query: 171 LEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLA------------------- 211
+ + H + +VH DLKP N LL LK +++ADFG
Sbjct: 268 ARGLHYLHSINIVHLDLKPANCLLTRDLK---LRIADFGCCHQLTPTGLDMGEREGGMAG 438
Query: 212 --IEVEGEQQAWFG-FAGTPGYLSPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDED 268
+E+ Q AW AGT Y +PE+L+ D+++ G+ L+ + P+
Sbjct: 439 NELELTPVQGAWKNELAGTLAYRAPELLKGLQPSVRSDVYSLGITLWQMCTRQGPYEGVP 618
Query: 269 QHR-LYQQIKAGAYDFPSP 286
H +YQ + P P
Sbjct: 619 AHAVVYQVVSKDLRPCPPP 675
>11780
Length = 1713
Score = 47.4 bits (111), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 43/152 (28%), Positives = 72/152 (47%), Gaps = 2/152 (1%)
Frame = +3
Query: 62 EEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLKHP 121
++ ++ E +GKG F V + + GQ A K + K R Q +EA + L+H
Sbjct: 597 QDLEIGEAIGKGDFGDVYK--GMYRGQPVAIKQLKDKD---RGEQSFLQEASVMTSLRHD 761
Query: 122 NIVRLHDSISEEGHHYLIFDLVTGGELFEDIVA--REYYSEADASHCIQQILEAVLHCHQ 179
N+VRL + E +L+ + + G L E + + R ++ D + A+ +
Sbjct: 762 NLVRLIGVVLGE-TIFLVTEFMGKGNLVEYLRSRGRSVITKKDQINFATDTCAAMEYLES 938
Query: 180 MGVVHRDLKPENLLLASKLKGAAVKLADFGLA 211
+VHRDL N+L+ K K++DFGLA
Sbjct: 939 KRLVHRDLAARNVLVHDDGK---AKVSDFGLA 1025
>36481
Length = 806
Score = 46.6 bits (109), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 45/150 (30%), Positives = 66/150 (44%), Gaps = 7/150 (4%)
Frame = +2
Query: 54 TITCTRFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKII-NTKKLSARDHQKLEREA 112
T+ T T + +L G+G F V +C +L G + A KII N K R+ KLE
Sbjct: 338 TMRGTSSTNDMKLCPHWGEGTFGKVVQCKDLLKGDDIALKIIKNVDKY--REAAKLEINV 511
Query: 113 RICRLLKHPN----IVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREY--YSEADASHC 166
K P+ V++ D GH + F ++ G +F+ + Y Y H
Sbjct: 512 LEKLREKDPHAKHMCVQMLDWFDYHGHVCISFHML-GLSVFDFLKDNSYGAYPIEQVRHI 688
Query: 167 IQQILEAVLHCHQMGVVHRDLKPENLLLAS 196
Q+ AV H+ + H DLKPEN+L
Sbjct: 689 SYQLCYAVNFLHENQLTHTDLKPENILFVD 778
>00394
Length = 548
Score = 46.2 bits (108), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 27/86 (31%), Positives = 44/86 (51%), Gaps = 5/86 (5%)
Frame = -2
Query: 68 EELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLH 127
+E+G+G+F V + + G A + KK + + Q+ + EA + + L+HPNIVR
Sbjct: 280 KEIGRGSFKTVYKGLDTELGVAVAWCELQDKKWNKAERQRFKEEAEMLKELQHPNIVRFF 101
Query: 128 DSISEEGHH-----YLIFDLVTGGEL 148
D E H L+ +L+T G L
Sbjct: 100 DYWEEHNHRNRKVIILVTELMTSGTL 23
>31789
Length = 676
Score = 45.8 bits (107), Expect = 4e-05, Method: Compositional matrix adjust.
Identities = 27/85 (31%), Positives = 43/85 (50%), Gaps = 5/85 (5%)
Frame = +2
Query: 69 ELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHD 128
E+G+G+F V + + G A + KK + + Q+ + EA + + L+HPNIVR D
Sbjct: 341 EIGRGSFKTVYKGLDTELGVAVAWCELQDKKWNKTERQRFKEEAEMLKELQHPNIVRFFD 520
Query: 129 SISEEGHH-----YLIFDLVTGGEL 148
E H L+ +L+T G L
Sbjct: 521 YWEEHNHRNRKVIILVTELMTSGTL 595
>31489
Length = 329
Score = 45.1 bits (105), Expect = 6e-05, Method: Composition-based stats.
Identities = 27/87 (31%), Positives = 48/87 (55%), Gaps = 6/87 (6%)
Frame = +3
Query: 113 RICRLLKHPNIVRLHDSIS-EEGHH-----YLIFDLVTGGELFEDIVAREYYSEADASHC 166
+I + KH NI+ + + + ++ +H +++FDL+ +L I + + +E +
Sbjct: 6 KILKHFKHDNIISIREILKPKDSYHDFKDIHVVFDLMES-DLHRIIYSDQPLTEEHIRYF 182
Query: 167 IQQILEAVLHCHQMGVVHRDLKPENLL 193
+ QIL + + H VVHRDLKP NLL
Sbjct: 183 LYQILRGLKYIHSANVVHRDLKPSNLL 263
>25019
Length = 730
Score = 44.7 bits (104), Expect = 8e-05, Method: Compositional matrix adjust.
Identities = 26/62 (41%), Positives = 34/62 (54%)
Frame = +3
Query: 190 ENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDLWA 249
EN+LL K VKL DFGL E + F GT Y++PE+L + +GK VD W+
Sbjct: 261 ENVLLD---KDGHVKLTDFGLCKEAITGTRVTHTFCGTIEYMAPEILTRTGHGKAVDWWS 431
Query: 250 CG 251
G
Sbjct: 432 LG 437
>07291
Length = 833
Score = 44.3 bits (103), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 29/118 (24%), Positives = 60/118 (50%), Gaps = 6/118 (5%)
Frame = +1
Query: 168 QQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGT 227
+QI + + + ++ VVHR+L N ++ + ++L+D+G+ + Q+++ +
Sbjct: 70 RQIADGMAYLQEVKVVHRNLAARNCIVT---EDGRLQLSDYGVTGSLF--PQSYYTADDS 234
Query: 228 PG-----YLSPEVLRKDPYGKPVDLWACGVILYILLV-GYPPFWDEDQHRLYQQIKAG 279
P +++PE + + D+WA GV+L+ LL G P+ D + L +K G
Sbjct: 235 PARDLVKWMAPETIDNFHFSSKSDVWAFGVVLWELLTRGITPYPDVENSSLLPYLKEG 408
>18481
Length = 437
Score = 43.9 bits (102), Expect = 2e-04, Method: Composition-based stats.
Identities = 35/130 (26%), Positives = 64/130 (49%), Gaps = 5/130 (3%)
Frame = -1
Query: 87 GQEYAAKI--INTKKLSARDHQKLEREARICRLL-KHPNIVRLHDSISEEGHHYLIFDLV 143
G++ A KI I+ K HQ L EA++ + +HP + ++ +E+ + L+ +L+
Sbjct: 410 GKDIAVKIEAIDVK------HQLLHYEAKVYEQIGRHPGLPTMYHYGTEKHFNALVMELL 249
Query: 144 TGG--ELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGA 201
ELF ++ + ++ Q+L + HQ +HRDLKP+N L+
Sbjct: 248 GPSLEELF--VICKRRFTLKTILMVSDQLLSRLEFIHQKCFIHRDLKPDNFLMGLGRHCH 75
Query: 202 AVKLADFGLA 211
+ + DFGL+
Sbjct: 74 RLYIIDFGLS 45
>32957
Length = 645
Score = 41.2 bits (95), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 21/51 (41%), Positives = 29/51 (56%)
Frame = +3
Query: 208 FGLAIEVEGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDLWACGVILYILL 258
F L +E G + F GT Y++PEV + YGK VD W G++L+ LL
Sbjct: 3 FALCVEKSGGRTR--TFCGTREYMAPEVHERKEYGKEVDWWGLGILLHELL 149
>07940
Length = 1336
Score = 41.2 bits (95), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 29/88 (32%), Positives = 46/88 (52%), Gaps = 6/88 (6%)
Frame = -3
Query: 183 VHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPG-----YLSPEVLR 237
+HRDL N+L+A + +K+ADFGL + QQ + T G +++PE L
Sbjct: 281 IHRDLAARNVLVAEEY---VLKIADFGLTRNL---QQFDYYRKTTDGRLPVKWMAPEALF 120
Query: 238 KDPYGKPVDLWACGVILY-ILLVGYPPF 264
Y D+W+ GV+L+ I +G P+
Sbjct: 119 DRKYTSKSDVWSYGVLLWEIFTLGGNPY 36
>08294
Length = 1849
Score = 40.8 bits (94), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 53/207 (25%), Positives = 84/207 (40%), Gaps = 17/207 (8%)
Frame = +2
Query: 121 PNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVA-REYYSEADASHCI-----------Q 168
PNIV E H+LI + G+L + ++A R + Q
Sbjct: 887 PNIVHFMGVCREAEPHFLITEYCDWGDLKQFLLATRNDNGRGRGTRVPALALSQKLGMGQ 1066
Query: 169 QILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTP 228
Q+ + G+VH DL N+LL S+++ +K+A L+ +V + P
Sbjct: 1067 QVAAGMEALSNQGLVHGDLAARNVLLTSRMQ---LKVARPALSGDVYASEYYPLHQRLVP 1237
Query: 229 -GYLSPEVLRKDPYGKPVDLWACGVILYILL----VGYPPFWDEDQHRLYQQIKAGAYDF 283
+L PE + +D D+WA GV L+ +L + Y DE+ R Q +A A D
Sbjct: 1238 LRWLPPEGVLEDSATTCGDVWAFGVFLWEVLQLADLPYRLMSDEEVLRSLQHSQA-ALDS 1414
Query: 284 PSPEWDTVTPEAKDLINKMLTINPSKR 310
P P L+ + PS+R
Sbjct: 1415 PD-----APPALLSLLQRCTAQQPSQR 1480
>12672
Length = 773
Score = 40.8 bits (94), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 29/92 (31%), Positives = 46/92 (50%), Gaps = 4/92 (4%)
Frame = +3
Query: 173 AVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEV---EGEQ-QAWFGFAGTP 228
+ + + G VHRD+K N+LL S+ K+ DF + EG+ Q GT
Sbjct: 27 GIQYLNDNGHVHRDIKTANILLDSEYTA---KVGDFATVVSAPSGEGKTVQNASVVIGTA 197
Query: 229 GYLSPEVLRKDPYGKPVDLWACGVILYILLVG 260
YL+PE + D K +D ++ GV+L ++ G
Sbjct: 198 AYLAPEAIHFDVSTK-LDSYSFGVVLLEVITG 290
>01106
Length = 878
Score = 40.8 bits (94), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 39/147 (26%), Positives = 67/147 (45%), Gaps = 12/147 (8%)
Frame = +3
Query: 60 FTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKL---SARDHQKLEREARICR 116
F Y + +LG G FS V C + + A K++ + + +A D KL + R
Sbjct: 312 FNGRYHVIRKLGWGHFSTVWLCWDLTCKRFVALKVVKSAQHYTETALDEVKLLKCVRESD 491
Query: 117 LLK--HPNIVRLHDSISEEG----HHYLIFDLVTGGELFEDIVAREYYSEA--DASHCIQ 168
+ V+L D G H ++F+ V G L + I+ Y + I+
Sbjct: 492 VADPARAKCVQLLDDFKISGVNGTHVAMVFE-VLGYNLLKLIIRSNYQGIPIHNVKLIIR 668
Query: 169 QILEAVLHCH-QMGVVHRDLKPENLLL 194
Q+LE + + H + ++H D+KPEN+L+
Sbjct: 669 QVLEGLSYMHAKCRIIHTDIKPENILI 749
>18287
Length = 678
Score = 39.7 bits (91), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 20/42 (47%), Positives = 26/42 (61%), Gaps = 1/42 (2%)
Frame = -3
Query: 292 TPEAKDLINKMLTINPSKRITAAEALKHPWISH-RSTVASCM 332
T EA L+ +ML +NP RI+A EAL HP++ R SCM
Sbjct: 436 THEAVRLLTRMLILNPKNRISAEEALSHPYLDEGRVRFHSCM 311
>29360
Length = 363
Score = 38.9 bits (89), Expect = 0.005, Method: Composition-based stats.
Identities = 32/123 (26%), Positives = 54/123 (43%), Gaps = 8/123 (6%)
Frame = +3
Query: 80 RCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLKHP-----NIVRLHDSISEEG 134
+C K + A KI+ AR Q E I + L N VR + +
Sbjct: 6 KCWKKGTSEIVAIKILKNHPSYARQGQI---EVSILQRLSQESADDYNFVRAFECFQHKN 176
Query: 135 HHYLIFDLVTGGELFEDIVAREYYSEADASHC---IQQILEAVLHCHQMGVVHRDLKPEN 191
H L+F+++ + D + + + + QQ+L A+ Q+G++H DLKPEN
Sbjct: 177 HTCLVFEMLE--QNLYDFLKQNKFQPLPLKYIRPITQQVLTALRKLKQLGLIHADLKPEN 350
Query: 192 LLL 194
++L
Sbjct: 351 IML 359
>11404
Length = 563
Score = 38.9 bits (89), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 37/149 (24%), Positives = 67/149 (44%), Gaps = 11/149 (7%)
Frame = +1
Query: 59 RFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLL 118
++ + Y++ +GKG+F V + ++ A KII KK Q E ++ ++
Sbjct: 130 KWADRYEIDSLIGKGSFGQVVKAYDHTDNEQVAIKIIKNKKPFLNQAQI---EVKLLEMM 300
Query: 119 KHPN------IVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADAS---HCIQQ 169
+ IVRL H L+F+L++ D++ + + QQ
Sbjct: 301 NRHDTDNKYYIVRLKRHFMFRSHLCLVFELLSYN--LYDLLRNTNFRGVSLNLTRKFAQQ 474
Query: 170 ILEAVLHCH--QMGVVHRDLKPENLLLAS 196
+ A+L +M ++H DLKPEN+LL +
Sbjct: 475 LCTALLFLATPEMSIIHCDLKPENILLCN 561
>23319
Length = 2235
Score = 38.9 bits (89), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 31/117 (26%), Positives = 51/117 (43%), Gaps = 26/117 (22%)
Frame = +3
Query: 233 PEVLRKDPYGKPVDLWACGVILYILLVGYPPFW----DEDQ-HRLYQQIKAGAYD----- 282
P+V Y +D+W+ G I L P + D+DQ R+++ + D
Sbjct: 3 PDVYXAKMYSTSIDMWSAGCIFAELANAGRPLFPGNDDDDQLKRIFKLLGTPTEDQWPGM 182
Query: 283 --------FP----SPEWDTVTPE----AKDLINKMLTINPSKRITAAEALKHPWIS 323
FP + W V P+ +DL+ +L PS R++A EAL+HP+ +
Sbjct: 183 TQLPNYRMFPMYHVTTTWQQVVPKLNSKGRDLLQCLLVCCPSDRMSADEALQHPYFA 353
>18401
Length = 463
Score = 38.1 bits (87), Expect = 0.009, Method: Compositional matrix adjust.
Identities = 31/140 (22%), Positives = 52/140 (37%), Gaps = 41/140 (29%)
Frame = -3
Query: 225 AGTPGYLSPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQ--------------- 269
T Y +PEV+ + + P D+W+ G I++ L GY F D
Sbjct: 449 VSTRHYRAPEVILELGWSHPCDVWSVGCIMFELYTGYTLFQTHDNKEHLAMMERILGSLP 270
Query: 270 HRLYQQIKAGAY----DFPSPEWDTVTPEAK----------------------DLINKML 303
+R+ ++ K Y PE ++ + DL+ K+L
Sbjct: 269 YRMAKKTKKQKYFHHGRLDVPERSSMARYVRENTKPLLRYVKDRENKDHQQLFDLMKKLL 90
Query: 304 TINPSKRITAAEALKHPWIS 323
S R + +AL+HP+ S
Sbjct: 89 AYEASSRYSLLQALQHPFFS 30
>20513
Length = 405
Score = 37.0 bits (84), Expect = 0.019, Method: Compositional matrix adjust.
Identities = 16/38 (42%), Positives = 24/38 (63%), Gaps = 1/38 (2%)
Frame = -1
Query: 287 EWDTVTPEA-KDLINKMLTINPSKRITAAEALKHPWIS 323
EWD +A D + ML +P +R TAA++L+HPW+
Sbjct: 315 EWDPKDAKAFADFLAPMLEFDPEQRATAAQSLQHPWLK 202
>37063
Length = 455
Score = 37.0 bits (84), Expect = 0.019, Method: Composition-based stats.
Identities = 26/83 (31%), Positives = 42/83 (50%), Gaps = 10/83 (12%)
Frame = -2
Query: 187 LKPENLLLASKLKGAAVKLADFGLA--IEVEGE---QQAWFGFAGTPGYLSPEVL----- 236
LKPEN+L + +K+ DF LA I +G+ G+ Y++PEV+
Sbjct: 454 LKPENILCEHLDEVVPLKICDFDLASGINCDGDGTKTPELLTPVGSAEYMAPEVVDAWVG 275
Query: 237 RKDPYGKPVDLWACGVILYILLV 259
Y K D+W+ G+IL +L++
Sbjct: 274 ESFSYDKRCDMWSLGIIL*VLVM 206
>18996
Length = 491
Score = 37.0 bits (84), Expect = 0.020, Method: Compositional matrix adjust.
Identities = 22/79 (27%), Positives = 39/79 (49%), Gaps = 3/79 (3%)
Frame = +2
Query: 183 VHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTP---GYLSPEVLRKD 239
+HRDL N+L+ + VK++DFGLA + ++G + + SPE +
Sbjct: 2 IHRDLAARNILVDR----SCVKISDFGLA-QFANADGYYYGISQRDIPIKWYSPEAIETC 166
Query: 240 PYGKPVDLWACGVILYILL 258
+ D+W+ GV L+ +
Sbjct: 167 KFSSYSDVWSYGVTLFEMF 223
>16350
Length = 1108
Score = 36.6 bits (83), Expect = 0.024, Method: Compositional matrix adjust.
Identities = 16/37 (43%), Positives = 24/37 (64%), Gaps = 1/37 (2%)
Frame = +3
Query: 287 EWDTVTPEA-KDLINKMLTINPSKRITAAEALKHPWI 322
EWD +A D + ML +P +R TAA++L+HPW+
Sbjct: 729 EWDPKDAKAFADFLAPMLEFDPEQRATAAQSLQHPWL 839
>15549
Length = 470
Score = 36.2 bits (82), Expect = 0.035, Method: Compositional matrix adjust.
Identities = 15/38 (39%), Positives = 24/38 (63%)
Frame = -1
Query: 58 TRFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKII 95
+RF +E++ E++GKG + +V R + QEYA K I
Sbjct: 230 SRFADEFECIEQMGKGGYGIVFRAKNKVDEQEYAVKRI 117
>07836
Length = 1478
Score = 35.8 bits (81), Expect = 0.041, Method: Compositional matrix adjust.
Identities = 52/195 (26%), Positives = 83/195 (42%), Gaps = 26/195 (13%)
Frame = -1
Query: 87 GQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVR-LHDSISEEG---HHYLIFDL 142
G+ A KI T + ++ E E LL+H NI+ + I G +LI D
Sbjct: 1478 GENVAVKIFFTTEEASWFR---ETELYQTVLLRHENILGFIAADIKGTGSWTQLFLITDY 1308
Query: 143 VTGGELFEDIVAREYYSEADASHCIQQILEAV-----LHCHQMG------VVHRDLKPEN 191
G L + +++R D+S + A+ LH G + HRD+K +N
Sbjct: 1307 HENGSLHDYLLSRVL----DSSEMLALAHSAICGLAHLHIEIFGTRGKPAIAHRDIKSKN 1140
Query: 192 LLLASKLKGAAVKLADFGLAIEVEGEQQ----AWFGFAGTPGYLSPEVLRK-------DP 240
+L+ K +AD GLA+ E A GT Y++PEVL D
Sbjct: 1139 ILVK---KNGTCCIADLGLAVRYISESNEVDVAPNPRQGTKRYMAPEVLEMLLNVKNFDA 969
Query: 241 YGKPVDLWACGVILY 255
+ K D++A G++++
Sbjct: 968 F-KQADMYAFGLVMW 927
>16708
Length = 1397
Score = 35.4 bits (80), Expect = 0.053, Method: Compositional matrix adjust.
Identities = 19/47 (40%), Positives = 30/47 (63%), Gaps = 1/47 (2%)
Frame = -1
Query: 166 CIQ-QILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLA 211
CI Q + A+ H H++GVVH D+K +N+L+ + KL D+G+A
Sbjct: 1082 CIAGQXVCALEHIHELGVVHMDVKADNVLVDAH---GNCKLTDYGIA 951
>00638
Length = 1595
Score = 35.4 bits (80), Expect = 0.053, Method: Compositional matrix adjust.
Identities = 11/32 (34%), Positives = 23/32 (71%)
Frame = +2
Query: 158 YSEADASHCIQQILEAVLHCHQMGVVHRDLKP 189
+++ D + ++++A+ CH MG++HRD+KP
Sbjct: 407 FTDYDIRFYLYELMKALDFCHSMGIMHRDVKP 502
>20559
Length = 430
Score = 35.0 bits (79), Expect = 0.073, Method: Composition-based stats.
Identities = 24/84 (28%), Positives = 41/84 (48%), Gaps = 5/84 (5%)
Frame = -2
Query: 62 EEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQK-----LEREARICR 116
++Y+ E++G+G + V + A +I+ K++ D + RE + +
Sbjct: 375 QKYEKLEKIGEGTYGTVFK-----AKNRETHEIVALKRVRLDDDDEGVPSSALREICLLK 211
Query: 117 LLKHPNIVRLHDSISEEGHHYLIF 140
LKH NIVRLHD + E L+F
Sbjct: 210 ELKHRNIVRLHDVLHSERKLTLVF 139
>20160
Length = 1277
Score = 34.7 bits (78), Expect = 0.11, Method: Compositional matrix adjust.
Identities = 13/30 (43%), Positives = 21/30 (70%)
Frame = +2
Query: 294 EAKDLINKMLTINPSKRITAAEALKHPWIS 323
+A DLIN+ + ++PS R A+ LKH W++
Sbjct: 335 DAADLINRCIALDPSTRPVLADILKHKWMT 424
>37602
Length = 804
Score = 33.9 bits (76), Expect = 0.17, Method: Compositional matrix adjust.
Identities = 22/75 (29%), Positives = 37/75 (49%), Gaps = 5/75 (6%)
Frame = -1
Query: 159 SEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADF-----GLAIE 213
+E + ++ L+ + + H+ G +HRD+K N+LL + VKLADF +
Sbjct: 225 TEPQIAFVCRETLKGLHYLHRRGKMHRDIKGANILLTEE---GDVKLADFWRVSSNHSHN 55
Query: 214 VEGEQQAWFGFAGTP 228
V+ + W F G P
Sbjct: 54 VQKKVFHWNAFIGWP 10
>32359
Length = 928
Score = 33.9 bits (76), Expect = 0.19, Method: Compositional matrix adjust.
Identities = 22/62 (35%), Positives = 33/62 (53%), Gaps = 5/62 (8%)
Frame = -1
Query: 70 LGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSA-----RDHQKLEREARICRLLKHPNIV 124
+G G+F VV Y AK+++T +L A +D + RE +I R L+H NIV
Sbjct: 406 IGNGSFGVV-----------YQAKLVDTSELVAIKKVLQDKRFKNRELQIMRKLEHQNIV 260
Query: 125 RL 126
+L
Sbjct: 259 KL 254
Score = 28.1 bits (61), Expect = 8.9, Method: Compositional matrix adjust.
Identities = 11/14 (78%), Positives = 13/14 (92%)
Frame = -3
Query: 181 GVVHRDLKPENLLL 194
GV HRD+KP+NLLL
Sbjct: 65 GVCHRDIKPQNLLL 24
>26009
Length = 886
Score = 33.5 bits (75), Expect = 0.23, Method: Compositional matrix adjust.
Identities = 13/33 (39%), Positives = 23/33 (69%)
Frame = +3
Query: 162 DASHCIQQILEAVLHCHQMGVVHRDLKPENLLL 194
+A ++Q++ A+ H +VHRD+KPEN+L+
Sbjct: 714 EAKSVMKQLVSALDFMHSKQLVHRDIKPENVLI 812
>35032
Length = 465
Score = 32.7 bits (73), Expect = 0.39, Method: Composition-based stats.
Identities = 12/26 (46%), Positives = 19/26 (73%)
Frame = +3
Query: 297 DLINKMLTINPSKRITAAEALKHPWI 322
DL+ ++L +PSKR+T AL HP++
Sbjct: 147 DLVKRLLNYDPSKRLTPXXALAHPFL 224
>33586
Length = 551
Score = 32.3 bits (72), Expect = 0.50, Method: Compositional matrix adjust.
Identities = 15/48 (31%), Positives = 25/48 (52%)
Frame = +2
Query: 123 IVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQI 170
IV LH + EG YLI + + GG+LF + ++E D + ++
Sbjct: 407 IVHLHYAFQTEGKLYLILEFLRGGDLFTRLSKEVMFTEEDVKFYLAEL 550
>17516
Length = 453
Score = 32.0 bits (71), Expect = 0.70, Method: Compositional matrix adjust.
Identities = 16/38 (42%), Positives = 24/38 (63%), Gaps = 1/38 (2%)
Frame = -3
Query: 224 FAGTPGYLSPEV-LRKDPYGKPVDLWACGVILYILLVG 260
AGTP Y++PEV L+K Y D+++ +IL+ L G
Sbjct: 439 LAGTPVYMAPEVLLQKGQYDMKADVYSLAIILWELWYG 326
>21800
Length = 855
Score = 31.6 bits (70), Expect = 0.78, Method: Compositional matrix adjust.
Identities = 23/79 (29%), Positives = 40/79 (50%), Gaps = 7/79 (8%)
Frame = +2
Query: 124 VRLHDSISEEG----HHYLIFDLVTGGELFEDIVAREYYSEA--DASHCIQQILEAVLHC 177
V+L D G H ++F+ V G L + I+ Y + I+Q+LE + +
Sbjct: 506 VQLLDDFKISGVNGTHVCMVFE-VLGYNLLKLIIRSNYQGIPVHNVKLIIRQVLEGLNYL 682
Query: 178 H-QMGVVHRDLKPENLLLA 195
H + ++H D+KPEN+L+
Sbjct: 683 HAKCNIIHTDIKPENILIC 739
>03106
Length = 2384
Score = 31.2 bits (69), Expect = 1.2, Method: Compositional matrix adjust.
Identities = 23/72 (31%), Positives = 33/72 (45%), Gaps = 1/72 (1%)
Frame = +2
Query: 246 DLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEA-KDLINKMLT 304
D+WA G + Y + PF+ Y Q +D PS D TPE L+ ML
Sbjct: 32 DVWAAGAVAYEIFGASNPFYSRLDSACYSQ-----HDLPSLPGD--TPEGVVRLVTSMLE 190
Query: 305 INPSKRITAAEA 316
+P++R +A A
Sbjct: 191 RDPAQRPSAVVA 226
>13305
Length = 549
Score = 30.8 bits (68), Expect = 1.2, Method: Compositional matrix adjust.
Identities = 15/51 (29%), Positives = 28/51 (54%), Gaps = 1/51 (1%)
Frame = +2
Query: 230 YLSPEVLRKDPYGKPVDLWACGVILY-ILLVGYPPFWDEDQHRLYQQIKAG 279
+++ E L + Y D+W+ GV+L+ I +G P+ D +L+ +K G
Sbjct: 23 WMAVESLFNNTYTTQSDVWSFGVVLWEIFTLGGTPYSSTDTQQLFAFLKDG 175
>03294
Length = 1684
Score = 30.4 bits (67), Expect = 2.0, Method: Compositional matrix adjust.
Identities = 27/109 (24%), Positives = 48/109 (44%), Gaps = 25/109 (22%)
Frame = -1
Query: 244 PVDLWACGVILYILLVGYPPF-WDEDQHRLYQQI---------------KAGAYDFPSPE 287
PVD+W+ G I +L+ P F D + +L++ K A++ P
Sbjct: 1675 PVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKLPAFNGMFPL 1496
Query: 288 W------DTVT---PEAKDLINKMLTINPSKRITAAEALKHPWISHRST 327
W +T+T DLI + L +P++RI+ + L+H + + T
Sbjct: 1495 WKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYFLNVDT 1349
>17011
Length = 1371
Score = 29.6 bits (65), Expect = 3.6, Method: Compositional matrix adjust.
Identities = 12/26 (46%), Positives = 17/26 (65%)
Frame = +1
Query: 297 DLINKMLTINPSKRITAAEALKHPWI 322
DLI ++T NP R+T AL HP++
Sbjct: 1 DLILDVVTFNPDHRLTPDLALSHPFL 78
>28494
Length = 463
Score = 28.9 bits (63), Expect = 5.5, Method: Composition-based stats.
Identities = 18/54 (33%), Positives = 24/54 (44%)
Frame = +3
Query: 293 PEAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNA 346
P NK L I+ + A + HP +SH ST A C R T+ L +A
Sbjct: 39 PPLAPFSNKYLAISVKPQDAVAWSGVHPSLSHTSTSAFCSTRNSTMSRLSSMHA 200
>14104
Length = 573
Score = 28.5 bits (62), Expect = 6.3, Method: Compositional matrix adjust.
Identities = 9/36 (25%), Positives = 22/36 (61%)
Frame = +1
Query: 287 EWDTVTPEAKDLINKMLTINPSKRITAAEALKHPWI 322
++ P+A + L ++P++R+T + L+HP++
Sbjct: 76 KFSNAAPQAMSFMQSCLKMDPAERLTCHQLLQHPYM 183
>32357
Length = 625
Score = 28.5 bits (62), Expect = 7.0, Method: Compositional matrix adjust.
Identities = 16/57 (28%), Positives = 33/57 (57%)
Frame = -2
Query: 63 EYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLK 119
+Y+L +++G G+F + V +G+E A K+ +L H +L E+++ R+L+
Sbjct: 435 KYRLMKKIGSGSFGEIYLGVHNTSGEEVAVKL----ELKNAKHPQLYYESKLYRVLQ 277
>32691
Length = 295
Score = 28.1 bits (61), Expect = 8.7, Method: Composition-based stats.
Identities = 14/36 (38%), Positives = 20/36 (55%)
Frame = +1
Query: 287 EWDTVTPEAKDLINKMLTINPSKRITAAEALKHPWI 322
+W T E D ++K L NP R TA + L+H +I
Sbjct: 82 KWST---EFIDFVSKCLVKNPENRATAVDLLQHDFI 180
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000305090 | hsapiens_gene_ensembl |
Calcium/calmodulin-dependent protein kinase type II alpha chain (EC
2.7.11.17) (CaM-kinase II alpha chain) (CaM kinase II alpha subunit)
(CaMK-II subunit alpha). [Source:Uniprot/SWISSPROT;Acc:Q9UQM7]
(489 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
15910 194 9e-50
01392 123 2e-28
12721 122 4e-28
01707 107 1e-23
01060 104 1e-22
09606 103 2e-22
03240 101 7e-22
30755 100 1e-21
21079 92 1e-21
13592 98 6e-21
17975 97 1e-20
18484 97 2e-20
14420 96 4e-20
26711 94 2e-19
14126 92 5e-19
00300 88 6e-18
21433 74 1e-16
13212 79 3e-15
13066 76 3e-14
09007 71 8e-13
01966 70 1e-12
31885 70 2e-12
00392 69 3e-12
28638 64 4e-12
00486 68 7e-12
27405 67 1e-11
19761 67 1e-11
01718 67 2e-11
38560 65 5e-11
18921 65 8e-11
06405 63 2e-10
21808 63 2e-10
26560 63 3e-10
29581 63 3e-10
21418 62 5e-10
36002 61 1e-09
20152 61 1e-09
12786 60 1e-09
29590 45 2e-09
19094 50 6e-09
01756 58 8e-09
04591 58 8e-09
27546 56 3e-08
11185 55 4e-08
18663 55 5e-08
20655 55 7e-08
04138 55 9e-08
27274 53 2e-07
31120 53 3e-07
02638 52 5e-07
17300 52 7e-07
32000 51 9e-07
04852 51 9e-07
19301 51 1e-06
03508 50 2e-06
28157 50 3e-06
17722 49 5e-06
14116 49 6e-06
00715 48 8e-06
11780 47 2e-05
36481 47 2e-05
00394 46 3e-05
31789 45 5e-05
07291 44 1e-04
31489 44 1e-04
25019 44 1e-04
18481 42 6e-04
32957 41 0.001
12672 40 0.002
07940 40 0.002
01106 40 0.002
08294 40 0.003
18287 39 0.003
29360 39 0.003
11404 39 0.005
23319 39 0.005
18401 38 0.009
20513 37 0.015
37063 37 0.016
16350 37 0.020
18996 37 0.026
15549 36 0.031
07836 35 0.051
16708 35 0.061
00638 35 0.061
20160 34 0.10
37602 34 0.15
32359 33 0.21
26009 33 0.28
35032 33 0.31
20559 32 0.39
17516 32 0.45
33586 32 0.50
03106 32 0.72
21800 32 0.80
13305 31 1.3
03294 30 2.2
28494 30 2.6
17011 29 3.5
14104 29 5.4
32357 28 6.3
32691 28 8.8
>15910
Length = 1361
Score = 194 bits (492), Expect = 9e-50, Method: Compositional matrix adjust.
Identities = 100/207 (48%), Positives = 133/207 (64%)
Frame = +2
Query: 96 ELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLA 155
ELF+ IV R Y+E DA+ I IL V + H GVVHRDLKPENLL + +KLA
Sbjct: 422 ELFDRIVTRGQYTEKDAARAISDILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLA 601
Query: 156 DFGLAIEVEGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWD 215
DFGL+ +E E Q GTPGY +PEVL+ D Y VD+W+ GVI YILL GY PF+
Sbjct: 602 DFGLSRIIEPEVQM-STVCGTPGYCAPEVLKGDKYTPSVDMWSVGVIAYILLCGYEPFFA 778
Query: 216 EDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPSKRITAAEALKHPWISHRS 275
E++ +Y++I G Y F W ++ AKD++ K+L I+P KR+TA EAL+ PW+ +
Sbjct: 779 ENEFEMYRKIIKGEYKFDEEYWSEISENAKDVVRKLLVIDPKKRLTATEALRLPWVKGVA 958
Query: 276 TVASCMHRQETVDCLKKFNARRKLKGA 302
T + M + T++ LK+FNARRKLK A
Sbjct: 959 TKTTNM--EITMNKLKEFNARRKLKCA 1033
>01392
Length = 1806
Score = 123 bits (308), Expect = 2e-28, Method: Compositional matrix adjust.
Identities = 74/191 (38%), Positives = 100/191 (52%), Gaps = 25/191 (13%)
Frame = -1
Query: 106 YYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLA--IEV 163
+ E +AS ++ I A+ H G+ HRDLKPEN+L VK+ DF LA I
Sbjct: 1803 HLCEREASLVVRHIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGISC 1624
Query: 164 EGEQQA---WFGFAGTPGYLSPEVLR-----KDPYGKPVDLWACGVILYILLVGYPPFWD 215
+G+ G+ Y++PEV+ Y K DLW+ G+ILYI+L GYPPF+
Sbjct: 1623 DGDGTKTPELLTPVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILYIMLCGYPPFYG 1444
Query: 216 ---ED------------QHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPSKRI 260
ED Q L+ I+ G Y FPS EW +++ AKDLI +L P KR
Sbjct: 1443 QCGEDCGWNRGEACHDCQDMLFNSIQDGHYKFPSQEWTSISSSAKDLIRHLLVREPRKRY 1264
Query: 261 TAAEALKHPWI 271
+AA+ LKHPWI
Sbjct: 1263 SAADVLKHPWI 1231
>12721
Length = 821
Score = 122 bits (305), Expect = 4e-28, Method: Compositional matrix adjust.
Identities = 75/251 (29%), Positives = 134/251 (53%), Gaps = 4/251 (1%)
Frame = +1
Query: 16 FEELGKGAFSVVRRCVKV-LAGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVR 74
F ++G+G+ +V C+ G++ A K ++ +K R + L E + R HPNIV
Sbjct: 103 FMKIGEGSTGIV--CIATSRDGRQMAVKKMDLRKQQRR--ELLFNEVVVMRDYHHPNIVE 270
Query: 75 LHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHR 134
+++S +++ + + GG L DIV E + + L+A+ H GV+HR
Sbjct: 271 MYNSYLVNDELWVVMEFMEGGAL-TDIVTNNRMDEVQIATVCRACLKALAFLHANGVIHR 447
Query: 135 DLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSPEVLRKDPYGKPV 194
D+K +++LL+ K VKL DFG +V + Q GTP +++PEV+ + PYG V
Sbjct: 448 DIKSDSILLSHDGK---VKLXDFGFCAQVTQDLQKRKSLVGTPYWMAPEVISRLPYGPEV 618
Query: 195 DLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT---VTPEAKDLINKM 251
D+W+ G+++ ++ PPF++E + ++I+ D P P+ ++P + I++M
Sbjct: 619 DIWSLGIMVMEMIDAEPPFFNEPPLQAMRRIR----DMPPPKLRNTHKISPRLQGFIDRM 786
Query: 252 LTINPSKRITA 262
L +P +R TA
Sbjct: 787 LVRDPHQRATA 819
>01707
Length = 757
Score = 107 bits (267), Expect = 1e-23, Method: Compositional matrix adjust.
Identities = 74/218 (33%), Positives = 106/218 (48%), Gaps = 4/218 (1%)
Frame = +1
Query: 11 EEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLKHP 70
E+Y+ ++G+G++ VV +C Q A K + + RE R+ + LKHP
Sbjct: 64 EKYEKIGKIGEGSYGVVFKCRNKETSQLVAIKKFVESEDDPLIKKIAMREIRMLKQLKHP 243
Query: 71 NIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMG 130
N+VRL + + +L+FD V L E E I Q L AV CHQ
Sbjct: 244 NLVRLIEVFRRKKRLHLVFDYVDHTLLNELDRYPRGLPEPMVKRIIYQTLLAVNFCHQYN 423
Query: 131 VVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSPEVLRKDP- 189
+HRD+KPEN+L+ + VKL DFG A + G + + T Y +PE+L D
Sbjct: 424 TIHRDVKPENILITRQ---GQVKLCDFGFARILTGPGDEYTDYVATRWYRAPELLVGDTQ 594
Query: 190 YGKPVDLWACGVILYILLVG---YPPFWDEDQHRLYQQ 224
YG PVD+WA G + LL G +P D DQ L ++
Sbjct: 595 YGPPVDVWAIGCVFAELLTGQALWPGRSDVDQLHLIRK 708
>01060
Length = 1800
Score = 104 bits (259), Expect = 1e-22, Method: Compositional matrix adjust.
Identities = 82/298 (27%), Positives = 137/298 (45%), Gaps = 37/298 (12%)
Frame = +1
Query: 16 FEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRL 75
F+++G+G + VV +C G++ A K I + RE + R L+H NIV L
Sbjct: 88 FQKIGEGTYGVVYKCRHRATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTNIVCL 267
Query: 76 HDSISEEGHHYLIFDLVTG-----------GELFEDIVAREYYSEADASHCIQQILEAVL 124
D I E+ +L+F+ ++ G + + + + Y + QI+ +
Sbjct: 268 EDVIMEDERLFLVFEFLSMDLKMYIDKFPEGVVLDRRLVKSY---------VFQIVTGIX 420
Query: 125 HCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSPEV 184
CHQ +VHRDLKP+NLL+ A+K+ADFG+A +A+ T Y +PE+
Sbjct: 421 FCHQRRIVHRDLKPQNLLINHT---GAIKIADFGMARTFALPVRAYTHEVVTLWYRAPEI 591
Query: 185 LR-KDPYGKPVDLWACGVILYILLVGYPPF-WDEDQHRLYQQI---------------KA 227
L Y PVD+W+ G I +L+ P F D + +L++ K
Sbjct: 592 LMGASKYSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKL 771
Query: 228 GAYDFPSPEW------DTVT---PEAKDLINKMLTINPSKRITAAEALKHPWISHRST 276
A++ P W +T+T DLI + L +P++RI+ + L+H + + T
Sbjct: 772 PAFNGMFPLWKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYFLNVDT 945
>09606
Length = 1300
Score = 103 bits (256), Expect = 2e-22, Method: Compositional matrix adjust.
Identities = 75/286 (26%), Positives = 134/286 (46%), Gaps = 28/286 (9%)
Frame = -3
Query: 11 EEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLKHP 70
E + L+EELGKG S++ + + A I K ++ R+ + HP
Sbjct: 1115 ENFVLYEELGKGEHSIIYKGRRKGTINFVAIHCIEKCK-----RPEVTNTVRMTHDISHP 951
Query: 71 NIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYY-SEADASHCIQQILEAVLHCHQM 129
N+V+ H+ H +L+ +L TGG L DI+A++++ E ++ + + H +
Sbjct: 950 NVVQFHEWYETSNHLWLVVELCTGGSL-ADILAQDHHLPETSIRDFGIHLVTGLHYIHSL 774
Query: 130 GVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGE--QQAWFGFA------------- 174
G++ DL+P +LL + +K ADFGL+ +VEGE ++ +F FA
Sbjct: 773 GILFHDLRPSKVLLDTS---GVLKFADFGLS-KVEGENLEELFFKFAEAGDQWNIQSAEE 606
Query: 175 --------GTPGYLSPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIK 226
G+P Y++PEV + DLWA G + Y + G+PPF E ++
Sbjct: 605 MMKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSGHPPFLGETYDITKDKVL 426
Query: 227 AGAYDFPSPEWDTV----TPEAKDLINKMLTINPSKRITAAEALKH 268
+ P + + +PE +L+ +L + ++R++ A +KH
Sbjct: 425 NKEFPLPKVKGSRLSAKPSPEFLNLLESLLQKDSTRRLSWASLVKH 288
>03240
Length = 1683
Score = 101 bits (251), Expect = 7e-22, Method: Compositional matrix adjust.
Identities = 79/284 (27%), Positives = 125/284 (44%), Gaps = 48/284 (16%)
Frame = -3
Query: 13 YQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARD---HQKLEREARICRLLKH 69
++ + LG GAF V C K G YA K + + R+ H K ER+ I +
Sbjct: 1285 FEKIKTLGVGAFGEVSLCRKNDTGMLYAMKTLRKSDVLKRNQVAHVKAERD--ILAEADN 1112
Query: 70 PNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQM 129
+V+L+ S + + Y + D V GG+L ++ E E A + ++++A+ H+M
Sbjct: 1111 EWVVKLYYSFQDHNYLYFVMDYVPGGDLMGLLIRMEILDEPLARFYVAELVQAIESVHRM 932
Query: 130 GVVHRDLKPENLLLASKLKGAAVKLADFGL-----------------------AIEV--- 163
G +HRD+KP+N+L+ + +KL DFGL ++EV
Sbjct: 931 GFIHRDIKPDNILID---RNGHIKLTDFGLCTGFRWTHNSKYYQRDGTHARQDSMEVKCQ 761
Query: 164 -----------------EGEQQAW-FGFAGTPGYLSPEVL-RKDPYGKPVDLWACGVILY 204
+ EQ+ GTP Y++PEVL R Y D W+ GVIL+
Sbjct: 760 LDEQCQCEILKPLERRRKREQRCLAHSLVGTPNYIAPEVLSRLGGYTSVCDWWSVGVILF 581
Query: 205 ILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLI 248
+LVG+PPF+ ++ P ++ AKDLI
Sbjct: 580 EMLVGHPPFYANTPAETQYKVINWKDMLKIPRESNLSQPAKDLI 449
>30755
Length = 1137
Score = 100 bits (249), Expect = 1e-21, Method: Compositional matrix adjust.
Identities = 58/160 (36%), Positives = 86/160 (53%), Gaps = 5/160 (3%)
Frame = +2
Query: 118 QILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTP 177
+I+ A+ + H G+++RDLK ENLLL K +K+ADFGL E + F GTP
Sbjct: 56 EIISALGYLHSQGIIYRDLKLENLLLD---KDGHIKVADFGLCKEDITYGRTTKTFCGTP 226
Query: 178 GYLSPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEW 237
YL+PEVL + YG+ VD W GV++Y ++ G PF++ D L+ I FP
Sbjct: 227 EYLAPEVLDDNDYGRAVDWWGTGVVMYEMICGRLPFYNRDHDVLFTLILVEDVKFPR--- 397
Query: 238 DTVTPEAKDLINKMLTINPSKRITAA-----EALKHPWIS 272
+T EAK L++ +L +P R+ E HP+ +
Sbjct: 398 -NITDEAKSLLSGLLAKDPRNRLGGGQDDVKEIQAHPFFA 514
>21079
Length = 878
Score = 92.4 bits (228), Expect(2) = 1e-21, Method: Compositional matrix adjust.
Identities = 52/145 (35%), Positives = 77/145 (53%), Gaps = 1/145 (0%)
Frame = +1
Query: 69 HPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREY-YSEADASHCIQQILEAVLHCH 127
HP ++ L D+ L+ + V GELFE ++ ++ +E D H ++QI V + H
Sbjct: 1 HPKLLMLWDAFEAPRTMVLVMEFVGAGELFERVIRDDFVLTERDCVHFVRQICSGVGYMH 180
Query: 128 QMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSPEVLRK 187
++H DLKPEN+L S +K+ DFGLA + F GTP +++PEV+
Sbjct: 181 TQSILHLDLKPENVLCVSD-NSNQIKIIDFGLARFYKPGDSLQVLF-GTPEFIAPEVVNY 354
Query: 188 DPYGKPVDLWACGVILYILLVGYPP 212
D D+W+ GVI YILL G P
Sbjct: 355 DEINFTTDMWSIGVICYILLSGLSP 429
Score = 28.9 bits (63), Expect(2) = 1e-21, Method: Compositional matrix adjust.
Identities = 18/56 (32%), Positives = 27/56 (48%)
Frame = +2
Query: 243 EAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRK 298
AKD I + KR+T + KH W++ + C ++ D L+ F ARRK
Sbjct: 518 NAKDFIGNC*SREKEKRMTIEQCDKHSWLAEQDQRIRC--KRLNTDRLRCFMARRK 679
>13592
Length = 980
Score = 98.2 bits (243), Expect = 6e-21, Method: Compositional matrix adjust.
Identities = 77/264 (29%), Positives = 126/264 (47%), Gaps = 11/264 (4%)
Frame = +2
Query: 18 ELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHD 77
++G+G F V V G+ A K I + R + + E +I +KH N+VR +
Sbjct: 5 KIGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETRALKNVAEELKILEGIKHKNLVRYY- 181
Query: 78 SISEEGHHYLIF-DLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDL 136
I LIF +L + G L + EA + Q+L V H+ G+VHRD+
Sbjct: 182 GIEVHREELLIFMELCSEGTLESLVELTGGLPEALSRRFTAQLLSGVAELHKHGIVHRDI 361
Query: 137 KPENLLLASKLKGAAVKLADFGLAIEVE------GEQQAWFGFAGTPGYLSPEVLRK--- 187
K N+ L ++KL DFG A++++ GE Q G+ GT Y++PEV K
Sbjct: 362 KTANIFLVD--GSNSLKLGDFGSAVKIQAHTTVPGELQ---GYVGTQAYMAPEVFTKTNS 526
Query: 188 DPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFP-SPEWDTVTPEAKD 246
D +G+ D+W+ G ++ + G P W + K G + P +PE +++ E D
Sbjct: 527 DGHGRLADIWSVGCVVVEMASGKRP-WAQFDSNFQIMFKVGMGEKPQAPE--SLSQEGHD 697
Query: 247 LINKMLTINPSKRITAAEALKHPW 270
I+ L +P +R++A E L+ +
Sbjct: 698 FIDHCLQHDPKQRLSAIELLEQNF 769
>17975
Length = 449
Score = 97.4 bits (241), Expect = 1e-20, Method: Composition-based stats.
Identities = 53/138 (38%), Positives = 82/138 (59%), Gaps = 1/138 (0%)
Frame = +3
Query: 24 FSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEG 83
F+VV+ V G++ A K+I+ KL L +E R +L++HPN+VRL++ I +
Sbjct: 6 FAVVKLARHVFTGEKVAVKVIDKTKLDEVSRSHLFQEVRCMKLVQHPNVVRLYEVIDTQT 185
Query: 84 HHYLIFDLVTGGELFEDIVARE-YYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLL 142
YLI +L GG++++ I+ E A +QI+EA+ +CH++ VVHRDLKPEN++
Sbjct: 186 KLYLILELGDGGDMYDYIMRHSGGLEEKLAKRYFRQIVEAISYCHKLHVVHRDLKPENVV 365
Query: 143 LASKLKGAAVKLADFGLA 160
K VKL DFG +
Sbjct: 366 FFE--KPGLVKLTDFGFS 413
>18484
Length = 635
Score = 96.7 bits (239), Expect = 2e-20, Method: Compositional matrix adjust.
Identities = 53/154 (34%), Positives = 82/154 (53%)
Frame = +1
Query: 107 YSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGE 166
+ E A+ +I + H G+++RDLK +N++L S+ +K+ADFG+ E
Sbjct: 34 FKEPVAAFYAAEIAVGLFFLHDQGIIYRDLKLDNVMLDSE---GHIKIADFGMCKEGMTG 204
Query: 167 QQAWFGFAGTPGYLSPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIK 226
F GTP Y++PE++ PY K VD WA GV+L+ +L G PPF ED+ L+ I
Sbjct: 205 DATTRTFCGTPDYIAPEIVLYQPYSKSVDWWAYGVLLFEMLAGQPPFDGEDEDELFSSIT 384
Query: 227 AGAYDFPSPEWDTVTPEAKDLINKMLTINPSKRI 260
+P ++ EA L +L NP+KR+
Sbjct: 385 DHNVSYPK----AMSREAVSLCKGLLMKNPTKRL 474
>14420
Length = 528
Score = 95.5 bits (236), Expect = 4e-20, Method: Compositional matrix adjust.
Identities = 55/176 (31%), Positives = 93/176 (52%), Gaps = 1/176 (0%)
Frame = +2
Query: 46 TKKLSARDHQKLE-REARICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAR 104
T LS + ++L E + R ++PNIV DS +++ + + GG L D+V
Sbjct: 5 TMNLSQQPKKELIINEILVMRENQNPNIVNYLDSYLVGEELWVVMEFLAGGSL-TDVVTE 181
Query: 105 EYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVE 164
E + ++ L+A+ H+ V+HRD+K +N+LL +VKL DFG ++
Sbjct: 182 TCMDEGQIAAVCRECLQALEFLHENQVIHRDIKSDNILLGMD---GSVKLTDFGFCAQLS 352
Query: 165 GEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHR 220
EQ GTP +++PEV+ + YG VD+W+ GV+ ++ G PP+ +E+ R
Sbjct: 353 PEQSKRSTMVGTPYWMAPEVVTRKQYGPTVDIWSLGVMCIEMIEGEPPYLNENPLR 520
>26711
Length = 405
Score = 93.6 bits (231), Expect = 2e-19, Method: Composition-based stats.
Identities = 51/134 (38%), Positives = 75/134 (55%), Gaps = 1/134 (0%)
Frame = -2
Query: 116 IQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAG 175
++Q+L+ + H H GVVH DLKP NLLL+ K +V+L DFGLA ++ Q+ + G
Sbjct: 398 VKQVLDILQHVHAQGVVHMDLKPSNLLLSGD-KLDSVQLIDFGLARKLYPPQETFLNH-G 225
Query: 176 TPGYLSPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFP-S 234
TPG+ SPE L P D+W GV+ YILL G PF + ++ + + F
Sbjct: 224 TPGFTSPEALDVKPISTASDVWGVGVLAYILLSGQSPFQADSATESLKKTQTCDWSFDVC 45
Query: 235 PEWDTVTPEAKDLI 248
P + ++ +AKD I
Sbjct: 44 PSFSNMSQDAKDFI 3
>14126
Length = 1265
Score = 92.0 bits (227), Expect = 5e-19, Method: Compositional matrix adjust.
Identities = 89/304 (29%), Positives = 135/304 (44%), Gaps = 43/304 (14%)
Frame = +3
Query: 11 EEYQLFEELGKGAFSVVRRCVKVLAGQEYAA-KIINTKKLSARDHQKLEREARICRLLK- 68
++Y+ +G GA+ V + + E+ A K I RE + + L+
Sbjct: 189 QKYEEVAVIGNGAYGTVYKARDLRNQGEFVAMKRIRLNNTEEGMPMMAIREISMLKQLEQ 368
Query: 69 --HPNIVRL----HDSISE-EGHHYLIFDLVTGGELFEDIVAREYYSEADA--------S 113
HPN+VRL H++I++ E L+F+ + D+ Y ++ +
Sbjct: 369 YEHPNVVRLLDVSHNTITDREIRLNLVFEYIE-----HDLAT--YLAKCPSPGLGPDRIK 527
Query: 114 HCIQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGF 173
+ Q+L V H +VHRDLKP+NLL++ K +KLADFGLA + A
Sbjct: 528 DLMLQLLNGVDFLHSNRIVHRDLKPQNLLIS---KDGRLKLADFGLA-RIYSFHMALTTV 695
Query: 174 AGTPGYLSPEVLRKDPYGKPVDLWACGVILYIL---------------------LVGYPP 212
T Y SPEVL + YG VD+W+CG I L ++G PP
Sbjct: 696 VVTLWYRSPEVLMQAEYGTSVDIWSCGCIFAELFTRRALFKGSSEFDQLKKIFEVIGLPP 875
Query: 213 F--WDE--DQHR-LYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPSKRITAAEALK 267
W E HR ++ PE D P+AKDL+ KML +RI++ E+L
Sbjct: 876 AGDWPEGVSVHRNSFRPTPPVPLQTLVPEMD---PQAKDLMEKMLVFKSGRRISSRESLL 1046
Query: 268 HPWI 271
HP++
Sbjct: 1047HPYL 1058
>00300
Length = 2318
Score = 88.2 bits (217), Expect = 6e-18, Method: Compositional matrix adjust.
Identities = 71/277 (25%), Positives = 130/277 (46%), Gaps = 10/277 (3%)
Frame = -1
Query: 4 ITCTRFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLER---E 60
I R +Q ++G+G F V V + G+ A K + K D Q+L E
Sbjct: 1679 INVRRVNFRWQRGNKIGEGQFGKVYTAVNMSTGELMALKEM---KFQPNDLQQLREMCDE 1509
Query: 61 ARICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQIL 120
+I ++H N+V+ + + + + G + E A+ E ++I+
Sbjct: 1508 IKIFEGIQHENLVKYYGVEVHKDEMLMFMEYCDTGTIEE--AAKMGLPEYLIRRYTREIV 1335
Query: 121 EAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQA---WFGFAGTP 177
AV H H+ +VHRD+K N+ L S VKL DFG +++++ + GT
Sbjct: 1334 LAVNHLHENSIVHRDIKGANIFLTSN---GHVKLGDFGCSVKLKSHTTMPGEFHNLVGTT 1164
Query: 178 GYLSPEVLRKDP---YGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQI-KAGAYDFP 233
Y++PEV ++ YG+ D+W+ G ++ + G P+ D D + YQ + K G P
Sbjct: 1163 AYMAPEVFTQNDQGGYGRAADIWSLGCVVIEMATGKRPWHDLDNN--YQIMYKVGIGHKP 990
Query: 234 SPEWDTVTPEAKDLINKMLTINPSKRITAAEALKHPW 270
+ D+++ E K ++ ++ +P++R A++ L H +
Sbjct: 989 AVP-DSLSVEGKHFLDLIMCHDPAQRALASQLLDHTF 882
>21433
Length = 590
Score = 74.3 bits (181), Expect(2) = 1e-16, Method: Compositional matrix adjust.
Identities = 48/142 (33%), Positives = 70/142 (49%), Gaps = 5/142 (3%)
Frame = +2
Query: 116 IQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAG 175
I Q+ A+ +CH V+HRD+KPEN +K+ADFG ++ ++ G
Sbjct: 185 IYQLSSALEYCHYRKVIHRDIKPEN---LLLGLKGDLKIADFGWSVHAPSSRRT--TMCG 349
Query: 176 TPGYLSPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSP 235
T YL PE++ + + VDLW+ GV+ Y LVG PP + SP
Sbjct: 350 TLDYLPPEMVEGKTHDENVDLWSLGVLCYEFLVGTPPL---------RPSPTRPPTPASP 502
Query: 236 EWDT-----VTPEAKDLINKML 252
W + VTP A+DLI+K+L
Sbjct: 503 RWTSGSPSIVTPGARDLISKLL 568
Score = 30.0 bits (66), Expect(2) = 1e-16, Method: Compositional matrix adjust.
Identities = 15/47 (31%), Positives = 26/47 (55%)
Frame = +3
Query: 55 QKLEREARICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDI 101
+L RE I L+H NI+R+ ++ YLI + GEL++++
Sbjct: 3 HQLRREIEIQSHLRHDNILRMFGYFHDKTRVYLILEFAPKGELYKEL 143
>13212
Length = 1067
Score = 79.3 bits (194), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 59/173 (34%), Positives = 88/173 (50%), Gaps = 9/173 (5%)
Frame = -1
Query: 108 SEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQ 167
+EA + ++ A+ H+ V+HRD+K N+LL VKLADFG++ + Q
Sbjct: 986 TEAQICYVCHEMCMALDFLHRHHVIHRDIKAGNVLLTI---DGEVKLADFGVSAKNTQTQ 816
Query: 168 QAWFGFAGTPGYLSPEV-----LRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLY 222
Q F GTP +++PEV L+ PY D+W+ GV L PP +++ H +
Sbjct: 815 QKRDTFIGTPYWMAPEVVLCETLKDTPYDFKADIWSLGVTLIEFAQIEPP--NKEMHPMR 642
Query: 223 QQIKAGAYDFPSPE----WDTVTPEAKDLINKMLTINPSKRITAAEALKHPWI 271
IK D P+ E W + KD I K L +P+ R TAAE L+HP++
Sbjct: 641 VLIKIHKSDPPTLEKPKKWTKL---FKDFIAKCLVKDPNLRPTAAELLEHPFM 492
>13066
Length = 551
Score = 76.3 bits (186), Expect = 3e-14, Method: Compositional matrix adjust.
Identities = 53/166 (31%), Positives = 78/166 (46%), Gaps = 5/166 (3%)
Frame = +3
Query: 40 AAKIINTKKLSARDHQKL-EREARICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELF 98
A KII+ +K +K RE + L HP I+++H + +++ G+L
Sbjct: 63 ACKIIDKEKAPVDFVEKFFPRELDLLTKLDHPYIIQIHSILQRXPKNFIFMRFAERGDLL 242
Query: 99 EDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFG 158
I + E A Q+ A+ + H V HRDLK EN+LL+S VKLADFG
Sbjct: 243 TYIQEVGFVKEKQAKIWFYQMTTALNYLHSYDVAHRDLKCENILLSSHFN---VKLADFG 413
Query: 159 LA---IEVEGEQQAWFGFAGTPGYLSPEVLRKDPYG-KPVDLWACG 200
A I GE+ + G+ Y +PE++ PY K D W+ G
Sbjct: 414 FACACITESGEKYMSRTYCGSAAYAAPEIVYGAPYAPKVADAWSLG 551
>09007
Length = 1440
Score = 71.2 bits (173), Expect = 8e-13, Method: Compositional matrix adjust.
Identities = 59/226 (26%), Positives = 105/226 (46%), Gaps = 13/226 (5%)
Frame = -1
Query: 15 LFEELGKGAFSVVRRCVKVLAGQE---YAAKIINTKKLSARDHQKLEREARICRLLKHPN 71
L + LG+G F VR+ + E A K ++ K+ +D Q+ +E I ++L H N
Sbjct: 867 LSKSLGQGHFGTVRQAIWTAESGEKVQVAVKCLSKDKIH-KDGQEFLKETAIMQMLDHEN 691
Query: 72 IVRLHDSISEEGHH-YLIFDLVTGGELFE---DIVAREYYSEADASHCIQQILEAVLHCH 127
IVR++ + + G L+ +L L E ++ AR +S QQ+ + + +
Sbjct: 690 IVRVYGVVMDNGADIMLVTELAPMRSLLECVKEVSARVDFSVPRLCDFSQQVCDGMSYLE 511
Query: 128 QMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEG-----EQQAWFGFAGTPGYLSP 182
+VHRDL N+LL SK K VK++D G++ + + Q + +P
Sbjct: 510 SKRLVHRDLAARNILLFSKSK---VKISDVGVSGALGAGKEYYQSQQTIHLQNAVAWCAP 340
Query: 183 EVLRKDPYGKPVDLWACGVILYILLV-GYPPFWDEDQHRLYQQIKA 227
E R + D+WA GV+L+ G+ P+ + ++ + + A
Sbjct: 339 ESFRNLCFSSASDVWAFGVLLWEFFTHGFQPWAGLNGQQIMEAVDA 202
>01966
Length = 1735
Score = 70.5 bits (171), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 57/190 (30%), Positives = 86/190 (45%), Gaps = 14/190 (7%)
Frame = -1
Query: 27 VRR---CVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEG 83
VRR C G++ A K I + RE + R L+H NIV L D I E+
Sbjct: 1672 VRRGL*CRHRATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTNIVCLEDVIMEDE 1493
Query: 84 HHYLIFDLVTG-----------GELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVV 132
+L+F+ ++ G + + + + Y + QI+ + CHQ +V
Sbjct: 1492 RLFLVFEFLSMDLKMYIDKFPEGVVLDRRLVKSY---------VFQIVTGINFCHQRRIV 1340
Query: 133 HRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSPEVLRKDPYGK 192
HRDLKP+NLL+ A+K+ADFG+A +A+ T Y +PE+L P
Sbjct: 1339 HRDLKPQNLLINHT---GAIKIADFGMARTFALPVRAYTHEVVTLWYRAPEIL-MGPQST 1172
Query: 193 PVDLWACGVI 202
P W CG +
Sbjct: 1171 P-PXWTCGAL 1145
Score = 31.6 bits (70), Expect = 0.75, Method: Compositional matrix adjust.
Identities = 32/125 (25%), Positives = 53/125 (42%), Gaps = 25/125 (20%)
Frame = -3
Query: 177 PGYLSPEVLRKDPYGKPVDLWACGVILYILLVGYPPF-WDEDQHRLYQQI---------- 225
PG P K Y PVD+W+ G I +L+ P F D + +L++
Sbjct: 1208 PGPRDPHGASK--YSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQT 1035
Query: 226 -----KAGAYDFPSPEW------DTVT---PEAKDLINKMLTINPSKRITAAEALKHPWI 271
K A++ P W +T+T DLI + L +P++RI+ + L+H +
Sbjct: 1034 WPEFHKLPAFNGMFPLWKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYF 855
Query: 272 SHRST 276
+ T
Sbjct: 854 LNVDT 840
>31885
Length = 529
Score = 70.1 bits (170), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 46/152 (30%), Positives = 76/152 (50%), Gaps = 5/152 (3%)
Frame = -2
Query: 67 LKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHC 126
L HP +V L + +E +++ DL GG+L + + E + Q+ + +
Sbjct: 501 LDHPFLVNLWYAFQDEEDLFMVVDLFLGGDLRYHMQQEVSFREDCVKFYLCQLALVLDYL 322
Query: 127 HQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSPEVL- 185
+VHRD+KP+N+LL + + DF +A ++E ++ A +GT Y++PEV
Sbjct: 321 RSQKIVHRDIKPDNILLDEQ---GHCHVTDFNIATQLEDDELA-TSTSGTRPYMAPEVYG 154
Query: 186 ----RKDPYGKPVDLWACGVILYILLVGYPPF 213
+ YG PVD W+ GV L+ LL PF
Sbjct: 153 VAINERRGYGFPVDWWSLGVSLFELLKKRRPF 58
>00392
Length = 668
Score = 69.3 bits (168), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 55/214 (25%), Positives = 104/214 (48%), Gaps = 8/214 (3%)
Frame = +3
Query: 44 INTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGHH-----YLIFDLVTGGELF 98
+ KK + + Q+ + EA + + L+HPNIVR D E H L+ +L+T G L
Sbjct: 33 LQDKKWNKAERQRFKEEAEMLKELQHPNIVRFFDYWEEHNHRNRKVIILVTELMTSGTLK 212
Query: 99 EDIVAREYYSEADASHCIQQILEAV--LHCHQMGVVHRDLKPENLLLASKLKGAAVKLAD 156
+ + + + +Q+L+ + LH V+HRDLK +N+ + +VK+ D
Sbjct: 213 TYLKRFKKPNVKILKNWCRQVLKGLYFLHTRTPPVIHRDLKCDNIFITG--PTGSVKIGD 386
Query: 157 FGLAIEVEGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWD- 215
GLA Q GTP +++PE + ++ Y + VD++A G+ + + P+ +
Sbjct: 387 LGLA--TLKNQSFAKSVIGTPEFMAPE-MYEEHYDEAVDVYAFGMCMLEMASSEYPYSEC 557
Query: 216 EDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLIN 249
+ ++Y+++ +G P E +D+I+
Sbjct: 558 SNAAQIYKRVTSGV--LPEALDKVAITEIRDIIH 653
>28638
Length = 1458
Score = 63.5 bits (153), Expect(2) = 4e-12, Method: Compositional matrix adjust.
Identities = 37/99 (37%), Positives = 57/99 (57%), Gaps = 2/99 (2%)
Frame = -1
Query: 117 QQILEAVLHCH--QMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFA 174
QQ+ A+L +M ++H DLKPEN+LL + K +A+K+ DFG + ++ Q + +
Sbjct: 816 QQLCTALLFLATPEMNIIHCDLKPENILLCNP-KRSAIKIVDFGSSCQLG---QRIYQYI 649
Query: 175 GTPGYLSPEVLRKDPYGKPVDLWACGVILYILLVGYPPF 213
+ Y SPEVL PY +D+W+ G IL + G PP
Sbjct: 648 QSRFYRSPEVLLGVPYDLAIDMWSLGCILVEMHTGEPPL 532
Score = 25.4 bits (54), Expect(2) = 4e-12, Method: Compositional matrix adjust.
Identities = 22/92 (23%), Positives = 42/92 (45%), Gaps = 6/92 (6%)
Frame = -3
Query: 8 RFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLL 67
++ + Y++ +GKG+F V + ++ A KII KK + + E ++ L+
Sbjct: 1156 KWLDRYEIDSLIGKGSFGQVVKAYDHGDQEQVAIKIIKNKKPFL---NQAQIEVKLLELM 986
Query: 68 KHPN------IVRLHDSISEEGHHYLIFDLVT 93
+ IVRL H L+F+L++
Sbjct: 985 NRHDADNXYYIVRLKRHFMFRNHLCLVFELLS 890
>00486
Length = 797
Score = 68.2 bits (165), Expect = 7e-12, Method: Compositional matrix adjust.
Identities = 35/102 (34%), Positives = 56/102 (54%)
Frame = -2
Query: 173 FAGTPGYLSPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDF 232
F GT Y++PE+L + +GK VD W+ G ++Y +L G PPF E++ + +I G +
Sbjct: 778 FCGTIEYMAPEILTRTGHGKAVDWWSLGALMYDMLTGSPPFTAENRKKTIDKILKGKLNL 599
Query: 233 PSPEWDTVTPEAKDLINKMLTINPSKRITAAEALKHPWISHR 274
P +T EA+ LI K+L NP++R+ P H+
Sbjct: 598 PP----YLTNEARGLIKKLLRKNPAERLGGGHDDSGPIKDHQ 485
>27405
Length = 532
Score = 67.4 bits (163), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 49/170 (28%), Positives = 79/170 (46%), Gaps = 5/170 (2%)
Frame = -3
Query: 23 AFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLL-----KHPNIVRLHD 77
F V C K G+ YA K ++ K++ + + L RI L P IV +
Sbjct: 530 GFGEVYGCRKADTGKMYAMKCLDKKRIKMKGGETLALNERIMLSLVSTGEGSPFIVCMTY 351
Query: 78 SISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLK 137
+ I DL+ GG+L + ++E + +++ + H H VV+RDLK
Sbjct: 350 AFQTPEKLCFILDLMNGGDLHYHLSQHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLK 171
Query: 138 PENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSPEVLRK 187
P N+LL + V+++D GLA + ++ GT GY++PEVL K
Sbjct: 170 PANILLD---ENGHVRISDLGLACDF--SKKKPHASVGTHGYMAPEVLMK 36
>19761
Length = 473
Score = 67.4 bits (163), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 44/130 (33%), Positives = 65/130 (50%)
Frame = -3
Query: 124 LHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSPE 183
+H H ++HRDLKP+N+ + K V+L D GLA ++ G GT YLSPE
Sbjct: 375 MHTHTPVILHRDLKPQNIYVTEK---GDVRLGDLGLARKLTGPADFATSQVGTIMYLSPE 205
Query: 184 VLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPE 243
+L + PY D+W+ G + Y + G + L Q+ G P P D + E
Sbjct: 204 ILSQQPYNSKSDIWSLGCVFYD-ITGKKGSDEMGVMFLLVQVMGGR-KLPLP--DHYSQE 37
Query: 244 AKDLINKMLT 253
+D I++MLT
Sbjct: 36 FRDTISRMLT 7
>01718
Length = 959
Score = 66.6 bits (161), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 54/192 (28%), Positives = 96/192 (50%), Gaps = 5/192 (2%)
Frame = +3
Query: 17 EELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLH 76
E++G G FS V + + GQ A K+ NT +++ H L RE ++ L+H NI+R
Sbjct: 165 EKIGAGFFSEVFKVTHRITGQVMALKM-NT--MTSNRHNML-REVQLLNRLQHANILRFM 332
Query: 77 DSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQIL---EAVLHCHQMGVVH 133
EG + + + + G L + + ++ E + IQ L + + H +H
Sbjct: 333 GVCVHEGQLHALTEYIPSGNLEQLLEKKD--EELPWTQRIQLTLGLARGLDYLHSTRFIH 506
Query: 134 RDLKPENLLLASKLK-GAAVKLADFGLAIEV-EGEQQAWFGFAGTPGYLSPEVLRKDPYG 191
RDL +N+L+ + G +ADFGLA ++ + + G+P +++PEVL Y
Sbjct: 507 RDLTSKNILIRREDNHGYHAVIADFGLATKIPDPLDKEKLPTVGSPYWMAPEVLNGHFYN 686
Query: 192 KPVDLWACGVIL 203
+ DL++ G+I+
Sbjct: 687 ERADLFSVGIIM 722
>38560
Length = 479
Score = 65.5 bits (158), Expect = 5e-11, Method: Compositional matrix adjust.
Identities = 44/121 (36%), Positives = 61/121 (50%), Gaps = 5/121 (4%)
Frame = -3
Query: 175 GTPGYLSPEVLRKDPY-GKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFP 233
G+P Y +PE++ Y G D+W+ GV+LY LL GY PF DE L Q+ + +
Sbjct: 399 GSPAYAAPELISGLEYLGSEADIWSMGVLLYALLCGYLPFDDEKXSHL*QKNQKRKDEV- 223
Query: 234 SPEWDTVTPEAKDLINKMLTINPSKRITAAEALKHPWISHRSTV----ASCMHRQETVDC 289
PEW ++ + L+ ML +PS RIT L H W++ V AS R DC
Sbjct: 222 -PEW--LSEDTTKLLEGMLQTDPSHRITIRRLLDHHWLNQGFNVPVEWASKYKRTLDEDC 52
Query: 290 L 290
L
Sbjct: 51 L 49
>18921
Length = 697
Score = 64.7 bits (156), Expect = 8e-11, Method: Compositional matrix adjust.
Identities = 47/201 (23%), Positives = 95/201 (47%), Gaps = 1/201 (0%)
Frame = +2
Query: 13 YQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNI 72
+ + +LG+G++ V + + GQ A K + D Q++ +E I + I
Sbjct: 35 FDILGKLGEGSYGSVFKSLHKETGQVLAIKQVPVDT----DLQEIIKEISIMQQCDSKYI 202
Query: 73 VRLHDSISEEGHHYLIFDLVTGGELFEDIVAR-EYYSEADASHCIQQILEAVLHCHQMGV 131
V+ + S + +++ + G + + + R + E + + + L+ + + H
Sbjct: 203 VKYYGSYFKNTDLWIVMEYCGAGSVSDIMRLRNKTLVEREIATILYYTLKGLXYLHSRRK 382
Query: 132 VHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSPEVLRKDPYG 191
+HRD+K N+LL ++ KLADFG+A ++ GTP +++PEV+++ Y
Sbjct: 383 IHRDIKAGNILLNNE---GHAKLADFGVAGQLTDTMAKRNTVIGTPYWMAPEVIQEIGYD 553
Query: 192 KPVDLWACGVILYILLVGYPP 212
D+W+ G+ + G PP
Sbjct: 554 CVADIWSLGITALEMAEGKPP 616
>06405
Length = 1965
Score = 63.2 bits (152), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 56/221 (25%), Positives = 96/221 (43%), Gaps = 4/221 (1%)
Frame = +1
Query: 12 EYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPN 71
E + LG G + V + + A K + ++ D EA I + +KHPN
Sbjct: 262 EIAMKHRLGGGQYGDVYEAMWKRYNKIVAVKTLKEDTMALND---FLEEAAIMKEMKHPN 432
Query: 72 IVRLHDSISEEGHHYLIFDLVTGGELFEDIVA--REYYSEADASHCIQQILEAVLHCHQM 129
+V+L + E Y++ + + G L + + + RE + QI + +
Sbjct: 433 LVQLLGVCTREPPFYIVTEFMPHGNLLDYLRSSTREENGPTALMYMATQIASGMAYLETK 612
Query: 130 GVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQ-QAWFGFAGTPGYLSPEVLRKD 188
+HRDL N L+A VK+ADFGLA ++ + A G + +PE L +
Sbjct: 613 NFIHRDLAARNCLVAD---SNMVKVADFGLARLMKDDTYTAHIGAKFPIKWTAPEGLAFN 783
Query: 189 PYGKPVDLWACGVILYILLV-GYPPFWDEDQHRLYQQIKAG 228
+ D+WA GV+L+ L G P+ + +Y ++ G
Sbjct: 784 RFSTRSDIWAFGVLLWELATYGMSPYPGVELTEVYHLLERG 906
>21808
Length = 1011
Score = 63.2 bits (152), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 51/195 (26%), Positives = 91/195 (46%), Gaps = 3/195 (1%)
Frame = +1
Query: 44 INTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVA 103
I T K D + EA+I + L+HP +++L+ +++ ++I +L+ G L E +
Sbjct: 34 IKTLKSGTMDPKDFLAEAQIMKKLRHPKLIQLYAVCTQDDPIFIITELMKNGSLLEFLQG 213
Query: 104 REYYSEADASHCI-QQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLA-I 161
+ + A I QI + + +HRDL N+L++ VK+ADFGLA +
Sbjct: 214 KGRVLKLPALIDIGAQIACGMAYLESQNYIHRDLAARNILVSDN---NTVKIADFGLARV 384
Query: 162 EVEGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDLWACGVILY-ILLVGYPPFWDEDQHR 220
E E +A G + +PE + + D+W+ G++L + G P+
Sbjct: 385 IKEDEYEARVGARFPIKWTAPEAANYNRFTIKSDVWSFGILLTETVTYGRVPYPGMTNAE 564
Query: 221 LYQQIKAGAYDFPSP 235
+ Q++ G Y P P
Sbjct: 565 VLHQVEHG-YRMPCP 606
>26560
Length = 398
Score = 63.2 bits (152), Expect = 3e-10, Method: Composition-based stats.
Identities = 38/113 (33%), Positives = 61/113 (53%), Gaps = 1/113 (0%)
Frame = -1
Query: 107 YSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGE 166
++E + +++ + H H VV+RDLKP N+LL + V+++D GLA + +
Sbjct: 365 FTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLD---ENGHVRISDLGLACDFSKK 195
Query: 167 QQAWFGFAGTPGYLSPEVLRK-DPYGKPVDLWACGVILYILLVGYPPFWDEDQ 218
+ GT GY++PEVL K Y D ++ G +LY LL G+ PF +Q
Sbjct: 194 RP--HASVGTHGYMAPEVLMKGQSYDSSADWFSFGCMLYKLLKGHSPFRQHNQ 42
>29581
Length = 1278
Score = 62.8 bits (151), Expect = 3e-10, Method: Compositional matrix adjust.
Identities = 65/243 (26%), Positives = 106/243 (43%), Gaps = 35/243 (14%)
Frame = -2
Query: 67 LKHPNIVRLHDSISEEGHHYLIF-------DLVTGGELFEDIVAREYYSEADASHCIQQI 119
L+H NIV+L + + + L DL + L +++ A +SE+ + Q+
Sbjct: 1184 LRHQNIVQLQEVVVGKSLDSLFLVMEYCEQDLAS---LLDNMPAP--FSESQVKCIVLQL 1020
Query: 120 LEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGY 179
L+ + + H+ ++HRDLK NLL+ K VK+ADFGLA Q+ T Y
Sbjct: 1019 LKGLRYLHEAFIIHRDLKVSNLLMTDK---GCVKIADFGLARNYGKPQKPMTPKVVTLWY 849
Query: 180 LSPEVL-RKDPYGKPVDLWACGVILYILLVGYPPFW----DEDQHRLYQQ--------IK 226
+PE+L + +D+W+ G IL LL G+ P D Q L + I
Sbjct: 848 RAPELLFGSKTHSTAIDMWSAGCILGELL-GHKPLMPGRSDLQQIELIMELLGTPNDTIW 672
Query: 227 AGAYDFPSPEWDTVTPEAKD---------------LINKMLTINPSKRITAAEALKHPWI 271
G P+ E T+ + + L+N + +P KR TA + L+H +
Sbjct: 671 PGFSQLPAFEQFTLKKQPYNNLRHTFPWLSESGIRLLNGLFMYHPQKRATAEDCLEHSYF 492
Query: 272 SHR 274
+
Sbjct: 491 KEQ 483
>21418
Length = 831
Score = 62.0 bits (149), Expect = 5e-10, Method: Compositional matrix adjust.
Identities = 25/57 (43%), Positives = 38/57 (66%)
Frame = +2
Query: 221 LYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPSKRITAAEALKHPWISHRSTV 277
+ ++I++G YDFP PEW V+ AKDLI ML ++PSKR+ + L++ WI+ V
Sbjct: 2 MKKRIRSGQYDFPDPEWTNVSQAAKDLIKGMLNVDPSKRLCIEDVLRNKWIAQYDAV 172
>36002
Length = 253
Score = 60.8 bits (146), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 26/56 (46%), Positives = 36/56 (64%)
Frame = +1
Query: 218 QHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPSKRITAAEALKHPWISH 273
Q L+ +I+ G Y FPS EW ++ AKDLI +L P KR +AA+ LKHPW+ +
Sbjct: 49 QELLFNRIQDGNYFFPSMEWSAISSSAKDLIRHLLVREPRKRYSAADVLKHPWVCN 216
>20152
Length = 445
Score = 60.8 bits (146), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 34/92 (36%), Positives = 48/92 (52%), Gaps = 1/92 (1%)
Frame = +1
Query: 182 PEVLRKDPYGKP-VDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTV 240
PE+L D Y P VD+W+ GVILY+L+VG PF + + I Y P +
Sbjct: 1 PEILLGDSYDAPAVDVWSLGVILYMLVVGEAPFQEANDSETLTMIMDCRYQIPP----HI 168
Query: 241 TPEAKDLINKMLTINPSKRITAAEALKHPWIS 272
+ + +DLI KML P R + L HPW++
Sbjct: 169 SHKCQDLIEKMLQREPVDRASLPHILAHPWLN 264
>12786
Length = 460
Score = 60.5 bits (145), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 38/119 (31%), Positives = 57/119 (47%), Gaps = 22/119 (18%)
Frame = -3
Query: 117 QQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWF--GFA 174
+++L AV H GV+H DLKP N +L + +KL DFG+A ++ ++ +
Sbjct: 389 REMLRAVKALHNEGVIHSDLKPANFMLVA----GNLKLIDFGIANTLQQDKTSVLKDSRV 222
Query: 175 GTPGYLSPEVL-----------------RKDP---YGKPVDLWACGVILYILLVGYPPF 213
GTP Y+SPE + R P G D+W+ G ILY ++ G PF
Sbjct: 221 GTPSYMSPEAIMAACDDSADDSMEEDGHRTKPKYKVGVRSDVWSLGCILYNMVYGRTPF 45
>29590
Length = 320
Score = 45.1 bits (105), Expect(2) = 2e-09, Method: Composition-based stats.
Identities = 17/39 (43%), Positives = 25/39 (64%)
Frame = +3
Query: 175 GTPGYLSPEVLRKDPYGKPVDLWACGVILYILLVGYPPF 213
GTP Y++PEVL +P D+W+ GV+ Y++L PF
Sbjct: 60 GTPDYVAPEVLDYEPLSIQTDMWSLGVLSYVMLTACSPF 176
Score = 35.0 bits (79), Expect(2) = 2e-09, Method: Composition-based stats.
Identities = 15/46 (32%), Positives = 24/46 (52%)
Frame = +2
Query: 216 EDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPSKRIT 261
++Q + I DFP + ++P AKD I K+L +P R+T
Sbjct: 182 DNQQETFCNISQVKLDFPDDLFSHISPHAKDFIKKLLVKDPRHRMT 319
>19094
Length = 898
Score = 49.7 bits (117), Expect(2) = 6e-09, Method: Compositional matrix adjust.
Identities = 27/93 (29%), Positives = 50/93 (53%)
Frame = +1
Query: 109 EADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQ 168
E + + + L+ + + H +HRD+K N+LL ++ KLADFG+A ++
Sbjct: 55 EREIATILYYTLKGL*YLHSRRKIHRDIKAGNILLNNE---GHAKLADFGVAGQLTDTMA 225
Query: 169 AWFGFAGTPGYLSPEVLRKDPYGKPVDLWACGV 201
GTP +++PEV+++ Y D+W+ G+
Sbjct: 226 KRNTVIGTPYWMAPEVIQEIGYDCVADIWSLGI 324
Score = 28.5 bits (62), Expect(2) = 6e-09, Method: Compositional matrix adjust.
Identities = 21/66 (31%), Positives = 29/66 (43%), Gaps = 3/66 (4%)
Frame = +3
Query: 209 GYPPFWDEDQHRLYQQIKAGAYDFPSPEW---DTVTPEAKDLINKMLTINPSKRITAAEA 265
G PP+ D R I P P + D + E D ++K L NP R TA +
Sbjct: 345 GKPPYGDIHPMRAIFMIPTK----PPPSFRQPDKWSTEFIDFVSKCLVKNPENRATAVDL 512
Query: 266 LKHPWI 271
L+H +I
Sbjct: 513 LQHDFI 530
>01756
Length = 1858
Score = 58.2 bits (139), Expect = 8e-09, Method: Compositional matrix adjust.
Identities = 56/214 (26%), Positives = 95/214 (44%), Gaps = 22/214 (10%)
Frame = -3
Query: 12 EYQLFEELGKGAFSVV--RRCVKVLAGQEYAAKIINTKKLSARDHQK-----LEREARIC 64
+Y+ ++G+G F V RC K +++ KK+ + ++ RE +I
Sbjct: 1739 KYEKLAKIGQGTFGEVFKARCKKT-------KQVVAMKKVLMDNEKEGFPITALREIKIL 1581
Query: 65 RLLKHPNIVRLHDSISEEG--------HHYLIFDLV---TGGELFEDIVAREYYSEADAS 113
+LL H N+V L + S + YL+F+ G L V ++ +
Sbjct: 1580 QLLNHENVVDLIEICSTKATSANRYKSMFYLVFEFCEHDLAGLLSNMSVV---FNLPEIK 1410
Query: 114 HCIQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGL--AIEVEGEQ-QAW 170
++Q++ + + H+ ++HRD+K N+L+ K +KLADFGL A V Q +
Sbjct: 1409 EVMKQLMNGLYYIHRNKILHRDMKAANILIT---KQGVLKLADFGLARAFSVNLRQPNRY 1239
Query: 171 FGFAGTPGYLSPEVLRKD-PYGKPVDLWACGVIL 203
T Y PE+L D Y +D W G I+
Sbjct: 1238 TNRVVTLWYRPPELLLGDRNYSTAIDQWGAGCIM 1137
>04591
Length = 1117
Score = 58.2 bits (139), Expect = 8e-09, Method: Compositional matrix adjust.
Identities = 48/157 (30%), Positives = 77/157 (49%), Gaps = 12/157 (7%)
Frame = -2
Query: 59 REARICRLLKHPNIVRLHDSI-SEEGHH-------YLIF---DLVTGGELFEDIVAREYY 107
RE +I + L+H N+V+L + ++ G + YLIF D G L R +
Sbjct: 1074 REIKILQQLEHENVVQLQEICHTQAGPYNRYKSTFYLIFEYCDYDLAGLLNN---LRVKF 904
Query: 108 SEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQ 167
S AD + + Q+L + + H ++HRD+K N+LL + +KLADFGL+ +
Sbjct: 903 SLADKKNLMSQLLNGLFYIHTKQILHRDIKAANILLT---RDGVLKLADFGLS-RPWVKS 736
Query: 168 QAWFGFAGTPGYLSPEVLRKD-PYGKPVDLWACGVIL 203
+ T Y PE+L + YG +D+W G I+
Sbjct: 735 KRLTNRVVTLWYRPPELLLGEREYGPEIDMWGVGCIM 625
>27546
Length = 426
Score = 56.2 bits (134), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 38/103 (36%), Positives = 53/103 (51%), Gaps = 1/103 (0%)
Frame = -1
Query: 59 REARICRLLKHPNIVRLHDSISEEGHHYLIF-DLVTGGELFEDIVAREYYSEADASHCIQ 117
RE I L HPNI+++H SI + G IF G++ I EA
Sbjct: 333 RELEILTRLDHPNIIQIH-SILQRGPKIFIFMRYAEKGDMLSHIKKTGPIDEAQTKVWFF 157
Query: 118 QILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLA 160
Q+ +A+ + H + HRDLK EN+LL+ +L VK+ADFG A
Sbjct: 156 QMAKALQYLHSHDIAHRDLKCENILLSKRLN---VKIADFGFA 37
>11185
Length = 473
Score = 55.5 bits (132), Expect = 4e-08, Method: Compositional matrix adjust.
Identities = 45/167 (26%), Positives = 75/167 (44%), Gaps = 23/167 (13%)
Frame = +1
Query: 125 HCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGE--QQAWFGFA-------- 174
+ H +G++ DL+P +LL + +K ADFGL+ +VEGE ++ +F FA
Sbjct: 46 YIHSLGILFHDLRPSKVLLDTS---GVLKFADFGLS-KVEGENLEELFFKFAEAGDQWNI 213
Query: 175 -------------GTPGYLSPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRL 221
G+P Y++PEV + DLWA G + Y + G RL
Sbjct: 214 QSAEEMMKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSG---------SRL 366
Query: 222 YQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPSKRITAAEALKH 268
+ PSPE+ +L+ +L + ++R++ A +KH
Sbjct: 367 SAK--------PSPEF-------LNLLESLLQKDSTRRLSWASLVKH 462
>18663
Length = 600
Score = 55.5 bits (132), Expect = 5e-08, Method: Compositional matrix adjust.
Identities = 34/97 (35%), Positives = 51/97 (52%), Gaps = 9/97 (9%)
Frame = +2
Query: 173 FAGTPGYLSPEVLRKDPYGKPVDLWACGVILYILLVGYPPF------WDEDQHR---LYQ 223
F GTP Y++PE+LR + YG VD WA GV+LY +L G PF + DQ+ L+Q
Sbjct: 8 FCGTPNYIAPEILRGEDYGFSVDWWALGVLLYEMLAGRSPFDIAGASENPDQNTEDYLFQ 187
Query: 224 QIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPSKRI 260
I P +++ +A ++ L NP+ R+
Sbjct: 188 VILEKTIRIPR----SLSVKAASVLKGFLNKNPADRL 286
>20655
Length = 1181
Score = 55.1 bits (131), Expect = 7e-08, Method: Compositional matrix adjust.
Identities = 21/57 (36%), Positives = 35/57 (61%)
Frame = +2
Query: 221 LYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPSKRITAAEALKHPWISHRSTV 277
+ ++I+ G Y+FP PEW V+ +AKDLI ML +P KR+ + + W++ + V
Sbjct: 2 MKKRIRNGQYEFPKPEWSRVSQDAKDLIRGMLCTDPDKRLNIKQVMASKWVADNTMV 172
>04138
Length = 800
Score = 54.7 bits (130), Expect = 9e-08, Method: Compositional matrix adjust.
Identities = 55/182 (30%), Positives = 77/182 (42%), Gaps = 34/182 (18%)
Frame = +1
Query: 121 EAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGL--AIEVEGEQ-QAWFGFAGTP 177
E + + H+ ++HRD+K N+L+ K +KLADFGL A V Q + T
Sbjct: 46 ERLYYIHRNKILHRDMKAANILIT---KQGVLKLADFGLARAFSVNLRQPNRYTNRVVTL 216
Query: 178 GYLSPEVLRKD-PYGKPVDLWACGVI---------------------LYILLVG--YPPF 213
Y PE+L D Y +D W G I L L G P
Sbjct: 217 WYRPPELLLGDRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQNQLTLITQLCGSITPEV 396
Query: 214 W-DEDQHRLYQQIK----AGAYDFPSPEWDTVT--PEAKDLINKMLTINPSKRITAAEAL 266
W Q +Y QIK AG + + + P DL ++L ++PS+RI+A EAL
Sbjct: 397 WPGVTQLSMYHQIKGALAAGRKNIIRDRFARILKDPYGLDLFERLLKMDPSQRISADEAL 576
Query: 267 KH 268
H
Sbjct: 577 NH 582
>27274
Length = 396
Score = 53.1 bits (126), Expect = 2e-07, Method: Composition-based stats.
Identities = 29/98 (29%), Positives = 52/98 (53%), Gaps = 8/98 (8%)
Frame = -1
Query: 183 EVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHR--------LYQQIKAGAYDFPS 234
E+LR +G VD+W+ G++L+ LL G+ PF E R +Y QI G+
Sbjct: 375 ELLRGQQHGPTVDMWSLGILLHELLSGHVPFEPERGSRQMARNMMAVYAQIIRGS-SRDV 199
Query: 235 PEWDTVTPEAKDLINKMLTINPSKRITAAEALKHPWIS 272
+ ++ D + +++ + +KR+T+ +A HPWI+
Sbjct: 198 CDGLALSTHGADFLRRLVQLEDTKRLTSQQAFSHPWIA 85
>31120
Length = 439
Score = 52.8 bits (125), Expect = 3e-07, Method: Composition-based stats.
Identities = 30/90 (33%), Positives = 47/90 (52%), Gaps = 1/90 (1%)
Frame = +1
Query: 183 EVLRKDPYG-KPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVT 241
EV+ PY K D W+ GVIL+I+L G PF D + ++L + ++ Y F D V+
Sbjct: 1 EVVCGVPYDPKMADAWSLGVILFIMLNGKMPFDDSNLNKLLEDQRSKKYSFRRKLQDLVS 180
Query: 242 PEAKDLINKMLTINPSKRITAAEALKHPWI 271
P A+ ++ +L N + R E L W+
Sbjct: 181 PNARSTVSVLLEPNSAMRWDLNEVLNCQWL 270
>02638
Length = 1490
Score = 52.0 bits (123), Expect = 5e-07, Method: Compositional matrix adjust.
Identities = 29/102 (28%), Positives = 52/102 (50%), Gaps = 1/102 (0%)
Frame = +1
Query: 175 GTPGYLSPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDED-QHRLYQQIKAGAYDFP 233
GT +++PEVLR + YG+ D+W+ G ++ + PP+ D + L K + P
Sbjct: 22 GTIAFMAPEVLRGESYGRACDVWSVGCVMIEMCTCRPPWNSHDISNHLALIFKIASSVDP 201
Query: 234 SPEWDTVTPEAKDLINKMLTINPSKRITAAEALKHPWISHRS 275
P + ++P +DL+ + L + R +A + L HP + S
Sbjct: 202 PPIPENMSPPVRDLMLRCLEQDSDFRPSAKDLLMHPLFTKYS 327
>17300
Length = 480
Score = 51.6 bits (122), Expect = 7e-07, Method: Composition-based stats.
Identities = 33/112 (29%), Positives = 56/112 (50%), Gaps = 7/112 (6%)
Frame = +1
Query: 129 MGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPG------YLSP 182
MG VHRDL N+L+ L K+ADFGL+ E+E + G T G + +P
Sbjct: 31 MGYVHRDLAARNILVNEIL---VCKVADFGLSREIESDTTE--GAYTTKGGKIPVRWTAP 195
Query: 183 EVLRKDPYGKPVDLWACGVILY-ILLVGYPPFWDEDQHRLYQQIKAGAYDFP 233
E + + D+W+ GV+++ ++ G P+W+ + + ++ G Y P
Sbjct: 196 EAIAYRKFTSASDVWSFGVVMWEVMSYGERPYWNWSNQDVIKAVEKG-YRLP 348
>32000
Length = 644
Score = 51.2 bits (121), Expect = 9e-07, Method: Compositional matrix adjust.
Identities = 44/148 (29%), Positives = 74/148 (50%), Gaps = 25/148 (16%)
Frame = -1
Query: 150 AAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSPEVLRK-DPYGKPVDLWACGVILYILLV 208
A +K+ADFGLA + + T Y +PE+L Y PVD+W+ G I ++
Sbjct: 578 AKMKIADFGLARVFGLPVRTYTHEVITLWYRAPEILLGCRFYSVPVDIWSLGCIFVEMMT 399
Query: 209 G---YPPFWDEDQ-HRLY-------QQIKAGAYDFPS-----PEW-----DTVTPEAK-- 245
+P + DQ +R++ +++ G P P+W +TV +K
Sbjct: 398 RRALFPGDSEIDQLYRIFRTLGTPDEKVWPGVSKLPDYKPTFPKWPLKNLETVVSLSKVG 219
Query: 246 -DLINKMLTINPSKRITAAEALKHPWIS 272
DL+ +MLT NP++RI+A A++HP+ +
Sbjct: 218 LDLLKRMLTYNPNRRISARSAMRHPYFN 135
>04852
Length = 1462
Score = 51.2 bits (121), Expect = 9e-07, Method: Compositional matrix adjust.
Identities = 50/218 (22%), Positives = 92/218 (42%), Gaps = 30/218 (13%)
Frame = +1
Query: 49 LSARDHQKLEREARICRLLK----HPNIVRLHDSISEEGHHYLIFDLVTGGEL------- 97
++A + Q +E ++ + +K H NIV ++ G ++I + G L
Sbjct: 55 VTAVEEQDFVQELQVMKAVKKMGSHINIVNFLGCCTQGGPLWVIVEFAKNGNLRDFLESC 234
Query: 98 ------FEDIVARE---YYSEADASHCIQ---------QILEAVLHCHQMGVVHRDLKPE 139
+ V+ + +Y++ H I+ QI + +HRDL
Sbjct: 235 RDGINGYGKFVSPQDPGWYTKTPGGHVIRRKNLLSYAFQIARGMEFLASRKCIHRDLAAR 414
Query: 140 NLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDLWAC 199
N+L+ + +K+ADFGL+ + ++ G +++PE L Y D+W+
Sbjct: 415 NVLVTEE---HVLKIADFGLSRTGDYYKKRSGGRLPVK-WMAPEALFDMRYTTKSDVWSF 582
Query: 200 GVILY-ILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPE 236
GV+L+ I +G P+ LY ++ AY P PE
Sbjct: 583 GVVLWEIFSLGGMPYASIPNEELYSKLLDDAYRMPRPE 696
>19301
Length = 712
Score = 51.2 bits (121), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 41/145 (28%), Positives = 65/145 (44%)
Frame = +2
Query: 16 FEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRL 75
E LG GA V + L +E A K + K E + R R L HPNI+
Sbjct: 320 LEWLGSGAQGAV--FLGKLCAEEVAVKKVRDIK---------ETDIRNLRKLNHPNIISF 466
Query: 76 HDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRD 135
++ + +I + G+L+E + + A +QI + + H ++HRD
Sbjct: 467 KGVCTQAPCYCIIMEYCPYGQLYEVLRDGKEIPPALVLDWSKQIASGMNYLHSHKIIHRD 646
Query: 136 LKPENLLLASKLKGAAVKLADFGLA 160
LK N+L+A K VK++DFG +
Sbjct: 647 LKSPNVLVA---KNDVVKISDFGTS 712
>03508
Length = 1463
Score = 50.4 bits (119), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 44/198 (22%), Positives = 90/198 (45%), Gaps = 5/198 (2%)
Frame = +1
Query: 11 EEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLKHP 70
++YQ+ +LG+G +S V + V + K + + + + L
Sbjct: 589 DDYQIVRKLGRGKYSEVFEAINVTNNE----KCVIKILKPVKKKKIKREIKILENLRGGT 756
Query: 71 NIVRL----HDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHC 126
N++ L D +S LIF+ V + + + +++ D + ++++A+ C
Sbjct: 757 NVITLLAIVKDPVSRTPA--LIFEHVNNTDFKQ---LYQTFTDYDIRFYLYELMKALDFC 921
Query: 127 HQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSPEVLR 186
H MG++HRD+KP N+++ + K ++L D+GLA E + + + PE+L
Sbjct: 922 HSMGIMHRDVKPHNVMIDHENK--KLRLIDWGLA-EFYHPGMEYNVRVASRYFKGPELLL 1092
Query: 187 K-DPYGKPVDLWACGVIL 203
Y +D+W+ G +
Sbjct: 1093DYQMYDYSLDMWSLGCMF 1146
Score = 36.6 bits (83), Expect = 0.023, Method: Compositional matrix adjust.
Identities = 13/32 (40%), Positives = 24/32 (75%)
Frame = +2
Query: 240 VTPEAKDLINKMLTINPSKRITAAEALKHPWI 271
++PEA D ++K+L + ++R+TA EA+ HP+
Sbjct: 1358 ISPEALDFLDKLLRYDHNERLTAREAMDHPYF 1453
>28157
Length = 400
Score = 49.7 bits (117), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 38/133 (28%), Positives = 67/133 (50%), Gaps = 6/133 (4%)
Frame = +3
Query: 37 QEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGE 96
++ A K I +++ Q+L++ +R+ HPNIV L+ + + L+ + GG
Sbjct: 3 KDVAVKRIESEQEKKSFMQELKQLSRV----SHPNIVCLYGACRDHPV-CLVMEYAEGGS 167
Query: 97 LFEDIVAREYYSEADASHCIQQILEAVL---HCHQM---GVVHRDLKPENLLLASKLKGA 150
L+ + + A+H + +L+ L + H M ++HRDLKP NLLL G
Sbjct: 168 LYNVLHGSGPQPQYTAAHAMNWLLQCALGVEYLHGMKPKALIHRDLKPPNLLLIQ--CGT 341
Query: 151 AVKLADFGLAIEV 163
+K+ DFG A ++
Sbjct: 342 KLKICDFGTACDI 380
>17722
Length = 680
Score = 48.9 bits (115), Expect = 5e-06, Method: Compositional matrix adjust.
Identities = 24/72 (33%), Positives = 40/72 (55%)
Frame = -3
Query: 194 VDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLT 253
VD W GV++Y ++ G PF++ D L++ I FP ++ EAK L++ +L
Sbjct: 678 VDWWGTGVVMYEMMCGRLPFYNRDHDVLFELILLQNVKFPR----NLSEEAKTLLSGLLA 511
Query: 254 INPSKRITAAEA 265
NP +R+ +EA
Sbjct: 510 KNPKRRLGGSEA 475
>14116
Length = 1017
Score = 48.5 bits (114), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 51/204 (25%), Positives = 88/204 (43%), Gaps = 13/204 (6%)
Frame = -1
Query: 17 EELGKGAFSVVRRCVKVLAGQE----YAAKIINTKKLSARDHQKLEREARICRLLKHPNI 72
EE+GKG F V+R L Q+ A K ++ + Q +EA I + H N+
Sbjct: 618 EEIGKGNFGCVKRGFLTLPEQKGDILVAVKTLHNNNPREIELQSFLQEALIMKDFHHSNV 439
Query: 73 VRLHD-SISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQ---QILEAVLHCHQ 128
+ L ++ + ++ + G+L I R+ + I I + +
Sbjct: 438 LTLIGICLNLDDMPLVVLPFMKHGDLLTYI--RDDQHQPTIKDLIMYGVDIARGMDYLAG 265
Query: 129 MGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPG-----YLSPE 183
+ VHRDL N +L VK+ADFGLA ++ ++ ++ +++ E
Sbjct: 264 LKFVHRDLAARNCMLDEDFH---VKVADFGLARDIY--EKEYYSSENKKAKLPVKWMALE 100
Query: 184 VLRKDPYGKPVDLWACGVILYILL 207
L K Y D+W+ GV+L+ LL
Sbjct: 99 SLEKGNYDSKTDVWSYGVVLWELL 28
>00715
Length = 1788
Score = 48.1 bits (113), Expect = 8e-06, Method: Compositional matrix adjust.
Identities = 50/200 (25%), Positives = 85/200 (42%), Gaps = 30/200 (15%)
Frame = +1
Query: 67 LKHPNIVRLHDSIS----EEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQ---QI 119
L+H N+V + + S E+G +L + V G L + ++ + D+S + Q+
Sbjct: 97 LRHVNVVSILGATSLHRFEDGA-WLAMEYV--GPLNLQTILNDHQQDIDSSMRLSLALQM 267
Query: 120 LEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLA------------------- 160
+ + H + +VH DLKP N LL LK +++ADFG
Sbjct: 268 ARGLHYLHSINIVHLDLKPANCLLTRDLK---LRIADFGCCHQLTPTGLDMGEREGGMAG 438
Query: 161 --IEVEGEQQAWFG-FAGTPGYLSPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDED 217
+E+ Q AW AGT Y +PE+L+ D+++ G+ L+ + P+
Sbjct: 439 NELELTPVQGAWKNELAGTLAYRAPELLKGLQPSVRSDVYSLGITLWQMCTRQGPYEGVP 618
Query: 218 QHR-LYQQIKAGAYDFPSPE 236
H +YQ + P P
Sbjct: 619 AHAVVYQVVSKDLRPCPPPS 678
>11780
Length = 1713
Score = 47.4 bits (111), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 43/152 (28%), Positives = 72/152 (47%), Gaps = 2/152 (1%)
Frame = +3
Query: 11 EEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLKHP 70
++ ++ E +GKG F V + + GQ A K + K R Q +EA + L+H
Sbjct: 597 QDLEIGEAIGKGDFGDVYK--GMYRGQPVAIKQLKDKD---RGEQSFLQEASVMTSLRHD 761
Query: 71 NIVRLHDSISEEGHHYLIFDLVTGGELFEDIVA--REYYSEADASHCIQQILEAVLHCHQ 128
N+VRL + E +L+ + + G L E + + R ++ D + A+ +
Sbjct: 762 NLVRLIGVVLGE-TIFLVTEFMGKGNLVEYLRSRGRSVITKKDQINFATDTCAAMEYLES 938
Query: 129 MGVVHRDLKPENLLLASKLKGAAVKLADFGLA 160
+VHRDL N+L+ K K++DFGLA
Sbjct: 939 KRLVHRDLAARNVLVHDDGK---AKVSDFGLA 1025
>36481
Length = 806
Score = 46.6 bits (109), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 45/150 (30%), Positives = 66/150 (44%), Gaps = 7/150 (4%)
Frame = +2
Query: 2 ATITCTRFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKII-NTKKLSARDHQKLERE 60
T+ T T + +L G+G F V +C +L G + A KII N K R+ KLE
Sbjct: 335 CTMRGTSSTNDMKLCPHWGEGTFGKVVQCKDLLKGDDIALKIIKNVDKY--REAAKLEIN 508
Query: 61 ARICRLLKHPN----IVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREY--YSEADASH 114
K P+ V++ D GH + F ++ G +F+ + Y Y H
Sbjct: 509 VLEKLREKDPHAKHMCVQMLDWFDYHGHVCISFHML-GLSVFDFLKDNSYGAYPIEQVRH 685
Query: 115 CIQQILEAVLHCHQMGVVHRDLKPENLLLA 144
Q+ AV H+ + H DLKPEN+L
Sbjct: 686 ISYQLCYAVNFLHENQLTHTDLKPENILFV 775
>00394
Length = 548
Score = 46.2 bits (108), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 27/86 (31%), Positives = 44/86 (51%), Gaps = 5/86 (5%)
Frame = -2
Query: 17 EELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLH 76
+E+G+G+F V + + G A + KK + + Q+ + EA + + L+HPNIVR
Sbjct: 280 KEIGRGSFKTVYKGLDTELGVAVAWCELQDKKWNKAERQRFKEEAEMLKELQHPNIVRFF 101
Query: 77 DSISEEGHH-----YLIFDLVTGGEL 97
D E H L+ +L+T G L
Sbjct: 100 DYWEEHNHRNRKVIILVTELMTSGTL 23
>31789
Length = 676
Score = 45.4 bits (106), Expect = 5e-05, Method: Compositional matrix adjust.
Identities = 27/85 (31%), Positives = 43/85 (50%), Gaps = 5/85 (5%)
Frame = +2
Query: 18 ELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHD 77
E+G+G+F V + + G A + KK + + Q+ + EA + + L+HPNIVR D
Sbjct: 341 EIGRGSFKTVYKGLDTELGVAVAWCELQDKKWNKTERQRFKEEAEMLKELQHPNIVRFFD 520
Query: 78 SISEEGHH-----YLIFDLVTGGEL 97
E H L+ +L+T G L
Sbjct: 521 YWEEHNHRNRKVIILVTELMTSGTL 595
>07291
Length = 833
Score = 44.3 bits (103), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 29/118 (24%), Positives = 60/118 (50%), Gaps = 6/118 (5%)
Frame = +1
Query: 117 QQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGT 176
+QI + + + ++ VVHR+L N ++ + ++L+D+G+ + Q+++ +
Sbjct: 70 RQIADGMAYLQEVKVVHRNLAARNCIVT---EDGRLQLSDYGVTGSLF--PQSYYTADDS 234
Query: 177 PG-----YLSPEVLRKDPYGKPVDLWACGVILYILLV-GYPPFWDEDQHRLYQQIKAG 228
P +++PE + + D+WA GV+L+ LL G P+ D + L +K G
Sbjct: 235 PARDLVKWMAPETIDNFHFSSKSDVWAFGVVLWELLTRGITPYPDVENSSLLPYLKEG 408
>31489
Length = 329
Score = 43.9 bits (102), Expect = 1e-04, Method: Composition-based stats.
Identities = 27/87 (31%), Positives = 48/87 (55%), Gaps = 6/87 (6%)
Frame = +3
Query: 62 RICRLLKHPNIVRLHDSIS-EEGHH-----YLIFDLVTGGELFEDIVAREYYSEADASHC 115
+I + KH NI+ + + + ++ +H +++FDL+ +L I + + +E +
Sbjct: 6 KILKHFKHDNIISIREILKPKDSYHDFKDIHVVFDLMES-DLHRIIYSDQPLTEEHIRYF 182
Query: 116 IQQILEAVLHCHQMGVVHRDLKPENLL 142
+ QIL + + H VVHRDLKP NLL
Sbjct: 183 LYQILRGLKYIHSANVVHRDLKPSNLL 263
>25019
Length = 730
Score = 43.9 bits (102), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 26/62 (41%), Positives = 34/62 (54%)
Frame = +3
Query: 139 ENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDLWA 198
EN+LL K VKL DFGL E + F GT Y++PE+L + +GK VD W+
Sbjct: 261 ENVLLD---KDGHVKLTDFGLCKEAITGTRVTHTFCGTIEYMAPEILTRTGHGKAVDWWS 431
Query: 199 CG 200
G
Sbjct: 432 LG 437
>18481
Length = 437
Score = 42.0 bits (97), Expect = 6e-04, Method: Compositional matrix adjust.
Identities = 35/130 (26%), Positives = 65/130 (50%), Gaps = 5/130 (3%)
Frame = -1
Query: 36 GQEYAAKI--INTKKLSARDHQKLEREARIC-RLLKHPNIVRLHDSISEEGHHYLIFDLV 92
G++ A KI I+ K HQ L EA++ ++ +HP + ++ +E+ + L+ +L+
Sbjct: 410 GKDIAVKIEAIDVK------HQLLHYEAKVYEQIGRHPGLPTMYHYGTEKHFNALVMELL 249
Query: 93 TGG--ELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGA 150
ELF ++ + ++ Q+L + HQ +HRDLKP+N L+
Sbjct: 248 GPSLEELF--VICKRRFTLKTILMVSDQLLSRLEFIHQKCFIHRDLKPDNFLMGLGRHCH 75
Query: 151 AVKLADFGLA 160
+ + DFGL+
Sbjct: 74 RLYIIDFGLS 45
>32957
Length = 645
Score = 40.8 bits (94), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 21/51 (41%), Positives = 29/51 (56%)
Frame = +3
Query: 157 FGLAIEVEGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDLWACGVILYILL 207
F L +E G + F GT Y++PEV + YGK VD W G++L+ LL
Sbjct: 3 FALCVEKSGGRTR--TFCGTREYMAPEVHERKEYGKEVDWWGLGILLHELL 149
>12672
Length = 773
Score = 40.4 bits (93), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 29/98 (29%), Positives = 48/98 (48%), Gaps = 4/98 (4%)
Frame = +3
Query: 116 IQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEV---EGEQ-QAWF 171
++ + + + G VHRD+K N+LL S+ K+ DF + EG+ Q
Sbjct: 9 VKGTASGIQYLNDNGHVHRDIKTANILLDSEYTA---KVGDFATVVSAPSGEGKTVQNAS 179
Query: 172 GFAGTPGYLSPEVLRKDPYGKPVDLWACGVILYILLVG 209
GT YL+PE + D K +D ++ GV+L ++ G
Sbjct: 180 VVIGTAAYLAPEAIHFDVSTK-LDSYSFGVVLLEVITG 290
>07940
Length = 1336
Score = 40.4 bits (93), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 30/102 (29%), Positives = 50/102 (49%), Gaps = 6/102 (5%)
Frame = -3
Query: 118 QILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTP 177
Q+ + + +HRDL N+L+A + +K+ADFGL + QQ + T
Sbjct: 323 QVARGMEYLASKQCIHRDLAARNVLVAEEY---VLKIADFGLTRNL---QQFDYYRKTTD 162
Query: 178 G-----YLSPEVLRKDPYGKPVDLWACGVILY-ILLVGYPPF 213
G +++PE L Y D+W+ GV+L+ I +G P+
Sbjct: 161 GRLPVKWMAPEALFDRKYTSKSDVWSYGVLLWEIFTLGGNPY 36
>01106
Length = 878
Score = 40.0 bits (92), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 39/148 (26%), Positives = 67/148 (45%), Gaps = 12/148 (8%)
Frame = +3
Query: 9 FTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKK---LSARDHQKLEREARICR 65
F Y + +LG G FS V C + + A K++ + + +A D KL + R
Sbjct: 312 FNGRYHVIRKLGWGHFSTVWLCWDLTCKRFVALKVVKSAQHYTETALDEVKLLKCVRESD 491
Query: 66 LLK--HPNIVRLHDSISEEG----HHYLIFDLVTGGELFEDIVAREYYSEA--DASHCIQ 117
+ V+L D G H ++F+ V G L + I+ Y + I+
Sbjct: 492 VADPARAKCVQLLDDFKISGVNGTHVAMVFE-VLGYNLLKLIIRSNYQGIPIHNVKLIIR 668
Query: 118 QILEAVLHCH-QMGVVHRDLKPENLLLA 144
Q+LE + + H + ++H D+KPEN+L+
Sbjct: 669 QVLEGLSYMHAKCRIIHTDIKPENILIC 752
>08294
Length = 1849
Score = 39.7 bits (91), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 54/212 (25%), Positives = 86/212 (40%), Gaps = 17/212 (8%)
Frame = +2
Query: 70 PNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVA-REYYSEADASHCI-----------Q 117
PNIV E H+LI + G+L + ++A R + Q
Sbjct: 887 PNIVHFMGVCREAEPHFLITEYCDWGDLKQFLLATRNDNGRGRGTRVPALALSQKLGMGQ 1066
Query: 118 QILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTP 177
Q+ + G+VH DL N+LL S+++ +K+A L+ +V + P
Sbjct: 1067 QVAAGMEALSNQGLVHGDLAARNVLLTSRMQ---LKVARPALSGDVYASEYYPLHQRLVP 1237
Query: 178 -GYLSPEVLRKDPYGKPVDLWACGVILYILL----VGYPPFWDEDQHRLYQQIKAGAYDF 232
+L PE + +D D+WA GV L+ +L + Y DE+ R Q +A A D
Sbjct: 1238 LRWLPPEGVLEDSATTCGDVWAFGVFLWEVLQLADLPYRLMSDEEVLRSLQHSQA-ALDS 1414
Query: 233 PSPEWDTVTPEAKDLINKMLTINPSKRITAAE 264
P P L+ + PS+R +E
Sbjct: 1415 PD-----APPALLSLLQRCTAQQPSQRPPFSE 1495
>18287
Length = 678
Score = 39.3 bits (90), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 20/42 (47%), Positives = 26/42 (61%), Gaps = 1/42 (2%)
Frame = -3
Query: 241 TPEAKDLINKMLTINPSKRITAAEALKHPWISH-RSTVASCM 281
T EA L+ +ML +NP RI+A EAL HP++ R SCM
Sbjct: 436 THEAVRLLTRMLILNPKNRISAEEALSHPYLDEGRVRFHSCM 311
>29360
Length = 363
Score = 39.3 bits (90), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 21/77 (27%), Positives = 38/77 (49%), Gaps = 3/77 (3%)
Frame = +3
Query: 71 NIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHC---IQQILEAVLHCH 127
N VR + + H L+F+++ D + + + + QQ+L A+
Sbjct: 138 NFVRAFECFQHKNHTCLVFEMLEQN--LYDFLKQNKFQPLPLKYIRPITQQVLTALRKLK 311
Query: 128 QMGVVHRDLKPENLLLA 144
Q+G++H DLKPEN++L
Sbjct: 312 QLGLIHADLKPENIMLV 362
>11404
Length = 563
Score = 38.9 bits (89), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 37/149 (24%), Positives = 67/149 (44%), Gaps = 11/149 (7%)
Frame = +1
Query: 8 RFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLL 67
++ + Y++ +GKG+F V + ++ A KII KK Q E ++ ++
Sbjct: 130 KWADRYEIDSLIGKGSFGQVVKAYDHTDNEQVAIKIIKNKKPFLNQAQI---EVKLLEMM 300
Query: 68 KHPN------IVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADAS---HCIQQ 118
+ IVRL H L+F+L++ D++ + + QQ
Sbjct: 301 NRHDTDNKYYIVRLKRHFMFRSHLCLVFELLSYN--LYDLLRNTNFRGVSLNLTRKFAQQ 474
Query: 119 ILEAVLHCH--QMGVVHRDLKPENLLLAS 145
+ A+L +M ++H DLKPEN+LL +
Sbjct: 475 LCTALLFLATPEMSIIHCDLKPENILLCN 561
>23319
Length = 2235
Score = 38.9 bits (89), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 31/117 (26%), Positives = 51/117 (43%), Gaps = 26/117 (22%)
Frame = +3
Query: 182 PEVLRKDPYGKPVDLWACGVILYILLVGYPPFW----DEDQ-HRLYQQIKAGAYD----- 231
P+V Y +D+W+ G I L P + D+DQ R+++ + D
Sbjct: 3 PDVYXAKMYSTSIDMWSAGCIFAELANAGRPLFPGNDDDDQLKRIFKLLGTPTEDQWPGM 182
Query: 232 --------FP----SPEWDTVTPE----AKDLINKMLTINPSKRITAAEALKHPWIS 272
FP + W V P+ +DL+ +L PS R++A EAL+HP+ +
Sbjct: 183 TQLPNYRMFPMYHVTTTWQQVVPKLNSKGRDLLQCLLVCCPSDRMSADEALQHPYFA 353
>18401
Length = 463
Score = 38.1 bits (87), Expect = 0.009, Method: Compositional matrix adjust.
Identities = 31/140 (22%), Positives = 52/140 (37%), Gaps = 41/140 (29%)
Frame = -3
Query: 174 AGTPGYLSPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQ--------------- 218
T Y +PEV+ + + P D+W+ G I++ L GY F D
Sbjct: 449 VSTRHYRAPEVILELGWSHPCDVWSVGCIMFELYTGYTLFQTHDNKEHLAMMERILGSLP 270
Query: 219 HRLYQQIKAGAY----DFPSPEWDTVTPEAK----------------------DLINKML 252
+R+ ++ K Y PE ++ + DL+ K+L
Sbjct: 269 YRMAKKTKKQKYFHHGRLDVPERSSMARYVRENTKPLLRYVKDRENKDHQQLFDLMKKLL 90
Query: 253 TINPSKRITAAEALKHPWIS 272
S R + +AL+HP+ S
Sbjct: 89 AYEASSRYSLLQALQHPFFS 30
>20513
Length = 405
Score = 37.4 bits (85), Expect = 0.015, Method: Compositional matrix adjust.
Identities = 16/37 (43%), Positives = 24/37 (64%), Gaps = 1/37 (2%)
Frame = -1
Query: 236 EWDTVTPEA-KDLINKMLTINPSKRITAAEALKHPWI 271
EWD +A D + ML +P +R TAA++L+HPW+
Sbjct: 315 EWDPKDAKAFADFLAPMLEFDPEQRATAAQSLQHPWL 205
>37063
Length = 455
Score = 37.0 bits (84), Expect = 0.016, Method: Composition-based stats.
Identities = 26/83 (31%), Positives = 42/83 (50%), Gaps = 10/83 (12%)
Frame = -2
Query: 136 LKPENLLLASKLKGAAVKLADFGLA--IEVEGE---QQAWFGFAGTPGYLSPEVL----- 185
LKPEN+L + +K+ DF LA I +G+ G+ Y++PEV+
Sbjct: 454 LKPENILCEHLDEVVPLKICDFDLASGINCDGDGTKTPELLTPVGSAEYMAPEVVDAWVG 275
Query: 186 RKDPYGKPVDLWACGVILYILLV 208
Y K D+W+ G+IL +L++
Sbjct: 274 ESFSYDKRCDMWSLGIIL*VLVM 206
>16350
Length = 1108
Score = 37.0 bits (84), Expect = 0.020, Method: Compositional matrix adjust.
Identities = 16/37 (43%), Positives = 24/37 (64%), Gaps = 1/37 (2%)
Frame = +3
Query: 236 EWDTVTPEA-KDLINKMLTINPSKRITAAEALKHPWI 271
EWD +A D + ML +P +R TAA++L+HPW+
Sbjct: 729 EWDPKDAKAFADFLAPMLEFDPEQRATAAQSLQHPWL 839
>18996
Length = 491
Score = 36.6 bits (83), Expect = 0.026, Method: Compositional matrix adjust.
Identities = 22/79 (27%), Positives = 39/79 (49%), Gaps = 3/79 (3%)
Frame = +2
Query: 132 VHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTP---GYLSPEVLRKD 188
+HRDL N+L+ + VK++DFGLA + ++G + + SPE +
Sbjct: 2 IHRDLAARNILVDR----SCVKISDFGLA-QFANADGYYYGISQRDIPIKWYSPEAIETC 166
Query: 189 PYGKPVDLWACGVILYILL 207
+ D+W+ GV L+ +
Sbjct: 167 KFSSYSDVWSYGVTLFEMF 223
>15549
Length = 470
Score = 36.2 bits (82), Expect = 0.031, Method: Composition-based stats.
Identities = 15/38 (39%), Positives = 24/38 (63%)
Frame = -1
Query: 7 TRFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKII 44
+RF +E++ E++GKG + +V R + QEYA K I
Sbjct: 230 SRFADEFECIEQMGKGGYGIVFRAKNKVDEQEYAVKRI 117
>07836
Length = 1478
Score = 35.4 bits (80), Expect = 0.051, Method: Compositional matrix adjust.
Identities = 45/165 (27%), Positives = 72/165 (43%), Gaps = 26/165 (15%)
Frame = -1
Query: 66 LLKHPNIVR-LHDSISEEG---HHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILE 121
LL+H NI+ + I G +LI D G L + +++R D+S +
Sbjct: 1397 LLRHENILGFIAADIKGTGSWTQLFLITDYHENGSLHDYLLSRVL----DSSEMLALAHS 1230
Query: 122 AV-----LHCHQMG------VVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQ-- 168
A+ LH G + HRD+K +N+L+ K +AD GLA+ E
Sbjct: 1229 AICGLAHLHIEIFGTRGKPAIAHRDIKSKNILVK---KNGTCCIADLGLAVRYISESNEV 1059
Query: 169 --AWFGFAGTPGYLSPEVLRK-------DPYGKPVDLWACGVILY 204
A GT Y++PEVL D + K D++A G++++
Sbjct: 1058 DVAPNPRQGTKRYMAPEVLEMLLNVKNFDAF-KQADMYAFGLVMW 927
>16708
Length = 1397
Score = 35.0 bits (79), Expect = 0.061, Method: Compositional matrix adjust.
Identities = 19/47 (40%), Positives = 30/47 (63%), Gaps = 1/47 (2%)
Frame = -1
Query: 115 CIQ-QILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLA 160
CI Q + A+ H H++GVVH D+K +N+L+ + KL D+G+A
Sbjct: 1082 CIAGQXVCALEHIHELGVVHMDVKADNVLVDAH---GNCKLTDYGIA 951
>00638
Length = 1595
Score = 35.0 bits (79), Expect = 0.061, Method: Compositional matrix adjust.
Identities = 11/32 (34%), Positives = 23/32 (71%)
Frame = +2
Query: 107 YSEADASHCIQQILEAVLHCHQMGVVHRDLKP 138
+++ D + ++++A+ CH MG++HRD+KP
Sbjct: 407 FTDYDIRFYLYELMKALDFCHSMGIMHRDVKP 502
>20160
Length = 1277
Score = 34.3 bits (77), Expect = 0.10, Method: Compositional matrix adjust.
Identities = 13/30 (43%), Positives = 21/30 (70%)
Frame = +2
Query: 243 EAKDLINKMLTINPSKRITAAEALKHPWIS 272
+A DLIN+ + ++PS R A+ LKH W++
Sbjct: 335 DAADLINRCIALDPSTRPVLADILKHKWMT 424
>37602
Length = 804
Score = 33.9 bits (76), Expect = 0.15, Method: Compositional matrix adjust.
Identities = 28/118 (23%), Positives = 50/118 (42%), Gaps = 5/118 (4%)
Frame = -1
Query: 65 RLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVL 124
R++ V DS ++ + GG + + +E + ++ L+ +
Sbjct: 354 RIVNIQTFVGYFDSYLRREKLWIAMEYCGGGSMQDIYHVTGPLTEPQIAFVCRETLKGLH 175
Query: 125 HCHQMGVVHRDLKPENLLLASKLKGAAVKLADF-----GLAIEVEGEQQAWFGFAGTP 177
+ H+ G +HRD+K N+LL + VKLADF + V+ + W F G P
Sbjct: 174 YLHRRGKMHRDIKGANILLTEE---GDVKLADFWRVSSNHSHNVQKKVFHWNAFIGWP 10
>32359
Length = 928
Score = 33.5 bits (75), Expect = 0.21, Method: Compositional matrix adjust.
Identities = 22/62 (35%), Positives = 33/62 (53%), Gaps = 5/62 (8%)
Frame = -1
Query: 19 LGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSA-----RDHQKLEREARICRLLKHPNIV 73
+G G+F VV Y AK+++T +L A +D + RE +I R L+H NIV
Sbjct: 406 IGNGSFGVV-----------YQAKLVDTSELVAIKKVLQDKRFKNRELQIMRKLEHQNIV 260
Query: 74 RL 75
+L
Sbjct: 259 KL 254
Score = 28.1 bits (61), Expect = 7.8, Method: Compositional matrix adjust.
Identities = 11/14 (78%), Positives = 13/14 (92%)
Frame = -3
Query: 130 GVVHRDLKPENLLL 143
GV HRD+KP+NLLL
Sbjct: 65 GVCHRDIKPQNLLL 24
>26009
Length = 886
Score = 33.1 bits (74), Expect = 0.28, Method: Compositional matrix adjust.
Identities = 13/33 (39%), Positives = 23/33 (69%)
Frame = +3
Query: 111 DASHCIQQILEAVLHCHQMGVVHRDLKPENLLL 143
+A ++Q++ A+ H +VHRD+KPEN+L+
Sbjct: 714 EAKSVMKQLVSALDFMHSKQLVHRDIKPENVLI 812
>35032
Length = 465
Score = 32.7 bits (73), Expect = 0.31, Method: Composition-based stats.
Identities = 12/26 (46%), Positives = 19/26 (73%)
Frame = +3
Query: 246 DLINKMLTINPSKRITAAEALKHPWI 271
DL+ ++L +PSKR+T AL HP++
Sbjct: 147 DLVKRLLNYDPSKRLTPXXALAHPFL 224
>20559
Length = 430
Score = 32.3 bits (72), Expect = 0.39, Method: Compositional matrix adjust.
Identities = 24/84 (28%), Positives = 41/84 (48%), Gaps = 5/84 (5%)
Frame = -2
Query: 11 EEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQK-----LEREARICR 65
++Y+ E++G+G + V + A +I+ K++ D + RE + +
Sbjct: 375 QKYEKLEKIGEGTYGTVFK-----AKNRETHEIVALKRVRLDDDDEGVPSSALREICLLK 211
Query: 66 LLKHPNIVRLHDSISEEGHHYLIF 89
LKH NIVRLHD + E L+F
Sbjct: 210 ELKHRNIVRLHDVLHSERKLTLVF 139
>17516
Length = 453
Score = 32.3 bits (72), Expect = 0.45, Method: Composition-based stats.
Identities = 16/38 (42%), Positives = 24/38 (63%), Gaps = 1/38 (2%)
Frame = -3
Query: 173 FAGTPGYLSPEV-LRKDPYGKPVDLWACGVILYILLVG 209
AGTP Y++PEV L+K Y D+++ +IL+ L G
Sbjct: 439 LAGTPVYMAPEVLLQKGQYDMKADVYSLAIILWELWYG 326
>33586
Length = 551
Score = 32.3 bits (72), Expect = 0.50, Method: Compositional matrix adjust.
Identities = 15/48 (31%), Positives = 25/48 (52%)
Frame = +2
Query: 72 IVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQI 119
IV LH + EG YLI + + GG+LF + ++E D + ++
Sbjct: 407 IVHLHYAFQTEGKLYLILEFLRGGDLFTRLSKEVMFTEEDVKFYLAEL 550
>03106
Length = 2384
Score = 31.6 bits (70), Expect = 0.72, Method: Compositional matrix adjust.
Identities = 23/72 (31%), Positives = 33/72 (45%), Gaps = 1/72 (1%)
Frame = +2
Query: 195 DLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEA-KDLINKMLT 253
D+WA G + Y + PF+ Y Q +D PS D TPE L+ ML
Sbjct: 32 DVWAAGAVAYEIFGASNPFYSRLDSACYSQ-----HDLPSLPGD--TPEGVVRLVTSMLE 190
Query: 254 INPSKRITAAEA 265
+P++R +A A
Sbjct: 191 RDPAQRPSAVVA 226
>21800
Length = 855
Score = 31.6 bits (70), Expect = 0.80, Method: Compositional matrix adjust.
Identities = 19/65 (29%), Positives = 33/65 (50%), Gaps = 3/65 (4%)
Frame = +2
Query: 83 GHHYLIFDLVTGGELFEDIVAREYYSEA--DASHCIQQILEAVLHCH-QMGVVHRDLKPE 139
G H + V G L + I+ Y + I+Q+LE + + H + ++H D+KPE
Sbjct: 545 GTHVCMVFEVLGYNLLKLIIRSNYQGIPVHNVKLIIRQVLEGLNYLHAKCNIIHTDIKPE 724
Query: 140 NLLLA 144
N+L+
Sbjct: 725 NILIC 739
>13305
Length = 549
Score = 30.8 bits (68), Expect = 1.3, Method: Compositional matrix adjust.
Identities = 15/51 (29%), Positives = 28/51 (54%), Gaps = 1/51 (1%)
Frame = +2
Query: 179 YLSPEVLRKDPYGKPVDLWACGVILY-ILLVGYPPFWDEDQHRLYQQIKAG 228
+++ E L + Y D+W+ GV+L+ I +G P+ D +L+ +K G
Sbjct: 23 WMAVESLFNNTYTTQSDVWSFGVVLWEIFTLGGTPYSSTDTQQLFAFLKDG 175
>03294
Length = 1684
Score = 30.0 bits (66), Expect = 2.2, Method: Compositional matrix adjust.
Identities = 27/109 (24%), Positives = 48/109 (44%), Gaps = 25/109 (22%)
Frame = -1
Query: 193 PVDLWACGVILYILLVGYPPF-WDEDQHRLYQQI---------------KAGAYDFPSPE 236
PVD+W+ G I +L+ P F D + +L++ K A++ P
Sbjct: 1675 PVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKLPAFNGMFPL 1496
Query: 237 W------DTVT---PEAKDLINKMLTINPSKRITAAEALKHPWISHRST 276
W +T+T DLI + L +P++RI+ + L+H + + T
Sbjct: 1495 WKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYFLNVDT 1349
>28494
Length = 463
Score = 29.6 bits (65), Expect = 2.6, Method: Composition-based stats.
Identities = 18/54 (33%), Positives = 24/54 (44%)
Frame = +3
Query: 242 PEAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNA 295
P NK L I+ + A + HP +SH ST A C R T+ L +A
Sbjct: 39 PPLAPFSNKYLAISVKPQDAVAWSGVHPSLSHTSTSAFCSTRNSTMSRLSSMHA 200
>17011
Length = 1371
Score = 29.3 bits (64), Expect = 3.5, Method: Compositional matrix adjust.
Identities = 12/26 (46%), Positives = 17/26 (65%)
Frame = +1
Query: 246 DLINKMLTINPSKRITAAEALKHPWI 271
DLI ++T NP R+T AL HP++
Sbjct: 1 DLILDVVTFNPDHRLTPDLALSHPFL 78
>14104
Length = 573
Score = 28.9 bits (63), Expect = 5.4, Method: Compositional matrix adjust.
Identities = 9/36 (25%), Positives = 22/36 (61%)
Frame = +1
Query: 236 EWDTVTPEAKDLINKMLTINPSKRITAAEALKHPWI 271
++ P+A + L ++P++R+T + L+HP++
Sbjct: 76 KFSNAAPQAMSFMQSCLKMDPAERLTCHQLLQHPYM 183
>32357
Length = 625
Score = 28.5 bits (62), Expect = 6.3, Method: Compositional matrix adjust.
Identities = 16/57 (28%), Positives = 33/57 (57%)
Frame = -2
Query: 12 EYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLK 68
+Y+L +++G G+F + V +G+E A K+ +L H +L E+++ R+L+
Sbjct: 435 KYRLMKKIGSGSFGEIYLGVHNTSGEEVAVKL----ELKNAKHPQLYYESKLYRVLQ 277
>32691
Length = 295
Score = 28.1 bits (61), Expect = 8.8, Method: Composition-based stats.
Identities = 14/36 (38%), Positives = 20/36 (55%)
Frame = +1
Query: 236 EWDTVTPEAKDLINKMLTINPSKRITAAEALKHPWI 271
+W T E D ++K L NP R TA + L+H +I
Sbjct: 82 KWST---EFIDFVSKCLVKNPENRATAVDLLQHDFI 180
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment:
Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schäffer, and Yi-Kuo Yu (2005) "Protein database
searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= ENSP00000381411 | hsapiens_gene_ensembl |
Calcium/calmodulin-dependent protein kinase type II alpha chain (EC
2.7.11.17) (CaM-kinase II alpha chain) (CaM kinase II alpha subunit)
(CaMK-II subunit alpha). [Source:Uniprot/SWISSPROT;Acc:Q9UQM7]
(478 letters)
Database: contigs50plus
39,407 sequences; 28,359,218 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
15910 194 9e-50
01392 123 2e-28
12721 122 3e-28
01707 107 1e-23
01060 104 9e-23
09606 103 2e-22
03240 101 6e-22
30755 100 1e-21
21079 92 1e-21
13592 99 5e-21
17975 98 9e-21
18484 97 2e-20
14420 96 4e-20
26711 94 2e-19
14126 92 5e-19
00300 89 5e-18
21433 74 1e-16
13212 79 3e-15
13066 76 3e-14
09007 71 9e-13
01966 71 1e-12
31885 70 2e-12
00392 69 3e-12
28638 64 4e-12
00486 68 7e-12
27405 68 9e-12
19761 67 1e-11
01718 67 2e-11
38560 65 5e-11
18921 65 9e-11
06405 64 2e-10
21808 63 2e-10
26560 63 2e-10
29581 63 3e-10
21418 62 4e-10
36002 61 1e-09
20152 61 1e-09
12786 60 1e-09
29590 45 2e-09
19094 50 6e-09
01756 59 6e-09
04591 58 7e-09
27546 56 3e-08
18663 55 5e-08
11185 55 5e-08
20655 55 7e-08
04138 55 8e-08
27274 53 2e-07
31120 53 3e-07
02638 52 6e-07
32000 51 9e-07
17300 51 9e-07
19301 51 1e-06
04852 51 1e-06
03508 50 1e-06
28157 50 3e-06
17722 49 4e-06
14116 48 7e-06
00715 48 7e-06
11780 47 2e-05
36481 47 2e-05
00394 46 3e-05
31789 45 5e-05
07291 44 1e-04
31489 44 1e-04
25019 44 1e-04
18481 42 6e-04
32957 41 0.001
12672 40 0.002
07940 40 0.002
01106 40 0.002
08294 40 0.003
29360 40 0.003
18287 39 0.003
11404 39 0.005
23319 39 0.005
18401 38 0.009
20513 37 0.015
37063 37 0.016
16350 37 0.019
18996 37 0.025
15549 36 0.039
07836 35 0.054
16708 35 0.058
00638 35 0.058
20160 35 0.094
37602 34 0.15
32359 33 0.21
35032 33 0.27
26009 33 0.29
20559 32 0.38
17516 32 0.44
33586 32 0.48
21800 32 0.76
03106 32 0.76
13305 31 1.4
03294 30 2.1
28494 30 2.7
17011 29 3.3
14104 29 5.2
32357 28 6.2
32691 28 9.1
>15910
Length = 1361
Score = 194 bits (492), Expect = 9e-50, Method: Compositional matrix adjust.
Identities = 100/207 (48%), Positives = 133/207 (64%)
Frame = +2
Query: 96 ELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLA 155
ELF+ IV R Y+E DA+ I IL V + H GVVHRDLKPENLL + +KLA
Sbjct: 422 ELFDRIVTRGQYTEKDAARAISDILHGVQYIHANGVVHRDLKPENLLYECMTDDSKLKLA 601
Query: 156 DFGLAIEVEGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWD 215
DFGL+ +E E Q GTPGY +PEVL+ D Y VD+W+ GVI YILL GY PF+
Sbjct: 602 DFGLSRIIEPEVQM-STVCGTPGYCAPEVLKGDKYTPSVDMWSVGVIAYILLCGYEPFFA 778
Query: 216 EDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPSKRITAAEALKHPWISHRS 275
E++ +Y++I G Y F W ++ AKD++ K+L I+P KR+TA EAL+ PW+ +
Sbjct: 779 ENEFEMYRKIIKGEYKFDEEYWSEISENAKDVVRKLLVIDPKKRLTATEALRLPWVKGVA 958
Query: 276 TVASCMHRQETVDCLKKFNARRKLKGA 302
T + M + T++ LK+FNARRKLK A
Sbjct: 959 TKTTNM--EITMNKLKEFNARRKLKCA 1033
>01392
Length = 1806
Score = 123 bits (309), Expect = 2e-28, Method: Compositional matrix adjust.
Identities = 74/191 (38%), Positives = 100/191 (52%), Gaps = 25/191 (13%)
Frame = -1
Query: 106 YYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLA--IEV 163
+ E +AS ++ I A+ H G+ HRDLKPEN+L VK+ DF LA I
Sbjct: 1803 HLCEREASLVVRHIARALDFLHSKGIAHRDLKPENILCEHLDDVVPVKICDFDLASGISC 1624
Query: 164 EGEQQA---WFGFAGTPGYLSPEVLR-----KDPYGKPVDLWACGVILYILLVGYPPFWD 215
+G+ G+ Y++PEV+ Y K DLW+ G+ILYI+L GYPPF+
Sbjct: 1623 DGDGTKTPELLTPVGSAEYMAPEVVDAWVGDSFSYDKRCDLWSLGIILYIMLCGYPPFYG 1444
Query: 216 ---ED------------QHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPSKRI 260
ED Q L+ I+ G Y FPS EW +++ AKDLI +L P KR
Sbjct: 1443 QCGEDCGWNRGEACHDCQDMLFNSIQDGHYKFPSQEWTSISSSAKDLIRHLLVREPRKRY 1264
Query: 261 TAAEALKHPWI 271
+AA+ LKHPWI
Sbjct: 1263 SAADVLKHPWI 1231
>12721
Length = 821
Score = 122 bits (306), Expect = 3e-28, Method: Compositional matrix adjust.
Identities = 75/251 (29%), Positives = 134/251 (53%), Gaps = 4/251 (1%)
Frame = +1
Query: 16 FEELGKGAFSVVRRCVKV-LAGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVR 74
F ++G+G+ +V C+ G++ A K ++ +K R + L E + R HPNIV
Sbjct: 103 FMKIGEGSTGIV--CIATSRDGRQMAVKKMDLRKQQRR--ELLFNEVVVMRDYHHPNIVE 270
Query: 75 LHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHR 134
+++S +++ + + GG L DIV E + + L+A+ H GV+HR
Sbjct: 271 MYNSYLVNDELWVVMEFMEGGAL-TDIVTNNRMDEVQIATVCRACLKALAFLHANGVIHR 447
Query: 135 DLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSPEVLRKDPYGKPV 194
D+K +++LL+ K VKL DFG +V + Q GTP +++PEV+ + PYG V
Sbjct: 448 DIKSDSILLSHDGK---VKLXDFGFCAQVTQDLQKRKSLVGTPYWMAPEVISRLPYGPEV 618
Query: 195 DLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT---VTPEAKDLINKM 251
D+W+ G+++ ++ PPF++E + ++I+ D P P+ ++P + I++M
Sbjct: 619 DIWSLGIMVMEMIDAEPPFFNEPPLQAMRRIR----DMPPPKLRNTHKISPRLQGFIDRM 786
Query: 252 LTINPSKRITA 262
L +P +R TA
Sbjct: 787 LVRDPHQRATA 819
>01707
Length = 757
Score = 107 bits (267), Expect = 1e-23, Method: Compositional matrix adjust.
Identities = 74/218 (33%), Positives = 106/218 (48%), Gaps = 4/218 (1%)
Frame = +1
Query: 11 EEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLKHP 70
E+Y+ ++G+G++ VV +C Q A K + + RE R+ + LKHP
Sbjct: 64 EKYEKIGKIGEGSYGVVFKCRNKETSQLVAIKKFVESEDDPLIKKIAMREIRMLKQLKHP 243
Query: 71 NIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMG 130
N+VRL + + +L+FD V L E E I Q L AV CHQ
Sbjct: 244 NLVRLIEVFRRKKRLHLVFDYVDHTLLNELDRYPRGLPEPMVKRIIYQTLLAVNFCHQYN 423
Query: 131 VVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSPEVLRKDP- 189
+HRD+KPEN+L+ + VKL DFG A + G + + T Y +PE+L D
Sbjct: 424 TIHRDVKPENILITRQ---GQVKLCDFGFARILTGPGDEYTDYVATRWYRAPELLVGDTQ 594
Query: 190 YGKPVDLWACGVILYILLVG---YPPFWDEDQHRLYQQ 224
YG PVD+WA G + LL G +P D DQ L ++
Sbjct: 595 YGPPVDVWAIGCVFAELLTGQALWPGRSDVDQLHLIRK 708
>01060
Length = 1800
Score = 104 bits (259), Expect = 9e-23, Method: Compositional matrix adjust.
Identities = 82/298 (27%), Positives = 137/298 (45%), Gaps = 37/298 (12%)
Frame = +1
Query: 16 FEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRL 75
F+++G+G + VV +C G++ A K I + RE + R L+H NIV L
Sbjct: 88 FQKIGEGTYGVVYKCRHRATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTNIVCL 267
Query: 76 HDSISEEGHHYLIFDLVTG-----------GELFEDIVAREYYSEADASHCIQQILEAVL 124
D I E+ +L+F+ ++ G + + + + Y + QI+ +
Sbjct: 268 EDVIMEDERLFLVFEFLSMDLKMYIDKFPEGVVLDRRLVKSY---------VFQIVTGIX 420
Query: 125 HCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSPEV 184
CHQ +VHRDLKP+NLL+ A+K+ADFG+A +A+ T Y +PE+
Sbjct: 421 FCHQRRIVHRDLKPQNLLINHT---GAIKIADFGMARTFALPVRAYTHEVVTLWYRAPEI 591
Query: 185 LR-KDPYGKPVDLWACGVILYILLVGYPPF-WDEDQHRLYQQI---------------KA 227
L Y PVD+W+ G I +L+ P F D + +L++ K
Sbjct: 592 LMGASKYSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKL 771
Query: 228 GAYDFPSPEW------DTVT---PEAKDLINKMLTINPSKRITAAEALKHPWISHRST 276
A++ P W +T+T DLI + L +P++RI+ + L+H + + T
Sbjct: 772 PAFNGMFPLWKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYFLNVDT 945
>09606
Length = 1300
Score = 103 bits (256), Expect = 2e-22, Method: Compositional matrix adjust.
Identities = 75/286 (26%), Positives = 134/286 (46%), Gaps = 28/286 (9%)
Frame = -3
Query: 11 EEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLKHP 70
E + L+EELGKG S++ + + A I K ++ R+ + HP
Sbjct: 1115 ENFVLYEELGKGEHSIIYKGRRKGTINFVAIHCIEKCK-----RPEVTNTVRMTHDISHP 951
Query: 71 NIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYY-SEADASHCIQQILEAVLHCHQM 129
N+V+ H+ H +L+ +L TGG L DI+A++++ E ++ + + H +
Sbjct: 950 NVVQFHEWYETSNHLWLVVELCTGGSL-ADILAQDHHLPETSIRDFGIHLVTGLHYIHSL 774
Query: 130 GVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGE--QQAWFGFA------------- 174
G++ DL+P +LL + +K ADFGL+ +VEGE ++ +F FA
Sbjct: 773 GILFHDLRPSKVLLDTS---GVLKFADFGLS-KVEGENLEELFFKFAEAGDQWNIQSAEE 606
Query: 175 --------GTPGYLSPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIK 226
G+P Y++PEV + DLWA G + Y + G+PPF E ++
Sbjct: 605 MMKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSGHPPFLGETYDITKDKVL 426
Query: 227 AGAYDFPSPEWDTV----TPEAKDLINKMLTINPSKRITAAEALKH 268
+ P + + +PE +L+ +L + ++R++ A +KH
Sbjct: 425 NKEFPLPKVKGSRLSAKPSPEFLNLLESLLQKDSTRRLSWASLVKH 288
>03240
Length = 1683
Score = 101 bits (252), Expect = 6e-22, Method: Compositional matrix adjust.
Identities = 79/287 (27%), Positives = 127/287 (44%), Gaps = 48/287 (16%)
Frame = -3
Query: 13 YQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARD---HQKLEREARICRLLKH 69
++ + LG GAF V C K G YA K + + R+ H K ER+ I +
Sbjct: 1285 FEKIKTLGVGAFGEVSLCRKNDTGMLYAMKTLRKSDVLKRNQVAHVKAERD--ILAEADN 1112
Query: 70 PNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQM 129
+V+L+ S + + Y + D V GG+L ++ E E A + ++++A+ H+M
Sbjct: 1111 EWVVKLYYSFQDHNYLYFVMDYVPGGDLMGLLIRMEILDEPLARFYVAELVQAIESVHRM 932
Query: 130 GVVHRDLKPENLLLASKLKGAAVKLADFGL-----------------------AIEV--- 163
G +HRD+KP+N+L+ + +KL DFGL ++EV
Sbjct: 931 GFIHRDIKPDNILID---RNGHIKLTDFGLCTGFRWTHNSKYYQRDGTHARQDSMEVKCQ 761
Query: 164 -----------------EGEQQAW-FGFAGTPGYLSPEVL-RKDPYGKPVDLWACGVILY 204
+ EQ+ GTP Y++PEVL R Y D W+ GVIL+
Sbjct: 760 LDEQCQCEILKPLERRRKREQRCLAHSLVGTPNYIAPEVLSRLGGYTSVCDWWSVGVILF 581
Query: 205 ILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKM 251
+LVG+PPF+ ++ P ++ AKDLI ++
Sbjct: 580 EMLVGHPPFYANTPAETQYKVINWKDMLKIPRESNLSQPAKDLILRL 440
>30755
Length = 1137
Score = 100 bits (249), Expect = 1e-21, Method: Compositional matrix adjust.
Identities = 58/160 (36%), Positives = 86/160 (53%), Gaps = 5/160 (3%)
Frame = +2
Query: 118 QILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTP 177
+I+ A+ + H G+++RDLK ENLLL K +K+ADFGL E + F GTP
Sbjct: 56 EIISALGYLHSQGIIYRDLKLENLLLD---KDGHIKVADFGLCKEDITYGRTTKTFCGTP 226
Query: 178 GYLSPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEW 237
YL+PEVL + YG+ VD W GV++Y ++ G PF++ D L+ I FP
Sbjct: 227 EYLAPEVLDDNDYGRAVDWWGTGVVMYEMICGRLPFYNRDHDVLFTLILVEDVKFPR--- 397
Query: 238 DTVTPEAKDLINKMLTINPSKRITAA-----EALKHPWIS 272
+T EAK L++ +L +P R+ E HP+ +
Sbjct: 398 -NITDEAKSLLSGLLAKDPRNRLGGGQDDVKEIQAHPFFA 514
>21079
Length = 878
Score = 92.4 bits (228), Expect(2) = 1e-21, Method: Compositional matrix adjust.
Identities = 52/145 (35%), Positives = 77/145 (53%), Gaps = 1/145 (0%)
Frame = +1
Query: 69 HPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREY-YSEADASHCIQQILEAVLHCH 127
HP ++ L D+ L+ + V GELFE ++ ++ +E D H ++QI V + H
Sbjct: 1 HPKLLMLWDAFEAPRTMVLVMEFVGAGELFERVIRDDFVLTERDCVHFVRQICSGVGYMH 180
Query: 128 QMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSPEVLRK 187
++H DLKPEN+L S +K+ DFGLA + F GTP +++PEV+
Sbjct: 181 TQSILHLDLKPENVLCVSD-NSNQIKIIDFGLARFYKPGDSLQVLF-GTPEFIAPEVVNY 354
Query: 188 DPYGKPVDLWACGVILYILLVGYPP 212
D D+W+ GVI YILL G P
Sbjct: 355 DEINFTTDMWSIGVICYILLSGLSP 429
Score = 28.9 bits (63), Expect(2) = 1e-21, Method: Compositional matrix adjust.
Identities = 18/56 (32%), Positives = 27/56 (48%)
Frame = +2
Query: 243 EAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRK 298
AKD I + KR+T + KH W++ + C ++ D L+ F ARRK
Sbjct: 518 NAKDFIGNC*SREKEKRMTIEQCDKHSWLAEQDQRIRC--KRLNTDRLRCFMARRK 679
>13592
Length = 980
Score = 98.6 bits (244), Expect = 5e-21, Method: Compositional matrix adjust.
Identities = 77/264 (29%), Positives = 126/264 (47%), Gaps = 11/264 (4%)
Frame = +2
Query: 18 ELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHD 77
++G+G F V V G+ A K I + R + + E +I +KH N+VR +
Sbjct: 5 KIGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETRALKNVAEELKILEGIKHKNLVRYY- 181
Query: 78 SISEEGHHYLIF-DLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDL 136
I LIF +L + G L + EA + Q+L V H+ G+VHRD+
Sbjct: 182 GIEVHREELLIFMELCSEGTLESLVELTGGLPEALSRRFTAQLLSGVAELHKHGIVHRDI 361
Query: 137 KPENLLLASKLKGAAVKLADFGLAIEVE------GEQQAWFGFAGTPGYLSPEVLRK--- 187
K N+ L ++KL DFG A++++ GE Q G+ GT Y++PEV K
Sbjct: 362 KTANIFLVD--GSNSLKLGDFGSAVKIQAHTTVPGELQ---GYVGTQAYMAPEVFTKTNS 526
Query: 188 DPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFP-SPEWDTVTPEAKD 246
D +G+ D+W+ G ++ + G P W + K G + P +PE +++ E D
Sbjct: 527 DGHGRLADIWSVGCVVVEMASGKRP-WAQFDSNFQIMFKVGMGEKPQAPE--SLSQEGHD 697
Query: 247 LINKMLTINPSKRITAAEALKHPW 270
I+ L +P +R++A E L+ +
Sbjct: 698 FIDHCLQHDPKQRLSAIELLEQNF 769
>17975
Length = 449
Score = 97.8 bits (242), Expect = 9e-21, Method: Composition-based stats.
Identities = 53/138 (38%), Positives = 82/138 (59%), Gaps = 1/138 (0%)
Frame = +3
Query: 24 FSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEG 83
F+VV+ V G++ A K+I+ KL L +E R +L++HPN+VRL++ I +
Sbjct: 6 FAVVKLARHVFTGEKVAVKVIDKTKLDEVSRSHLFQEVRCMKLVQHPNVVRLYEVIDTQT 185
Query: 84 HHYLIFDLVTGGELFEDIVARE-YYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLL 142
YLI +L GG++++ I+ E A +QI+EA+ +CH++ VVHRDLKPEN++
Sbjct: 186 KLYLILELGDGGDMYDYIMRHSGGLEEKLAKRYFRQIVEAISYCHKLHVVHRDLKPENVV 365
Query: 143 LASKLKGAAVKLADFGLA 160
K VKL DFG +
Sbjct: 366 FFE--KPGLVKLTDFGFS 413
>18484
Length = 635
Score = 96.7 bits (239), Expect = 2e-20, Method: Compositional matrix adjust.
Identities = 53/154 (34%), Positives = 82/154 (53%)
Frame = +1
Query: 107 YSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGE 166
+ E A+ +I + H G+++RDLK +N++L S+ +K+ADFG+ E
Sbjct: 34 FKEPVAAFYAAEIAVGLFFLHDQGIIYRDLKLDNVMLDSE---GHIKIADFGMCKEGMTG 204
Query: 167 QQAWFGFAGTPGYLSPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIK 226
F GTP Y++PE++ PY K VD WA GV+L+ +L G PPF ED+ L+ I
Sbjct: 205 DATTRTFCGTPDYIAPEIVLYQPYSKSVDWWAYGVLLFEMLAGQPPFDGEDEDELFSSIT 384
Query: 227 AGAYDFPSPEWDTVTPEAKDLINKMLTINPSKRI 260
+P ++ EA L +L NP+KR+
Sbjct: 385 DHNVSYPK----AMSREAVSLCKGLLMKNPTKRL 474
>14420
Length = 528
Score = 95.5 bits (236), Expect = 4e-20, Method: Compositional matrix adjust.
Identities = 55/176 (31%), Positives = 93/176 (52%), Gaps = 1/176 (0%)
Frame = +2
Query: 46 TKKLSARDHQKLE-REARICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAR 104
T LS + ++L E + R ++PNIV DS +++ + + GG L D+V
Sbjct: 5 TMNLSQQPKKELIINEILVMRENQNPNIVNYLDSYLVGEELWVVMEFLAGGSL-TDVVTE 181
Query: 105 EYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVE 164
E + ++ L+A+ H+ V+HRD+K +N+LL +VKL DFG ++
Sbjct: 182 TCMDEGQIAAVCRECLQALEFLHENQVIHRDIKSDNILLGMD---GSVKLTDFGFCAQLS 352
Query: 165 GEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHR 220
EQ GTP +++PEV+ + YG VD+W+ GV+ ++ G PP+ +E+ R
Sbjct: 353 PEQSKRSTMVGTPYWMAPEVVTRKQYGPTVDIWSLGVMCIEMIEGEPPYLNENPLR 520
>26711
Length = 405
Score = 93.6 bits (231), Expect = 2e-19, Method: Composition-based stats.
Identities = 51/134 (38%), Positives = 75/134 (55%), Gaps = 1/134 (0%)
Frame = -2
Query: 116 IQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAG 175
++Q+L+ + H H GVVH DLKP NLLL+ K +V+L DFGLA ++ Q+ + G
Sbjct: 398 VKQVLDILQHVHAQGVVHMDLKPSNLLLSGD-KLDSVQLIDFGLARKLYPPQETFLNH-G 225
Query: 176 TPGYLSPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFP-S 234
TPG+ SPE L P D+W GV+ YILL G PF + ++ + + F
Sbjct: 224 TPGFTSPEALDVKPISTASDVWGVGVLAYILLSGQSPFQADSATESLKKTQTCDWSFDVC 45
Query: 235 PEWDTVTPEAKDLI 248
P + ++ +AKD I
Sbjct: 44 PSFSNMSQDAKDFI 3
>14126
Length = 1265
Score = 92.0 bits (227), Expect = 5e-19, Method: Compositional matrix adjust.
Identities = 89/304 (29%), Positives = 135/304 (44%), Gaps = 43/304 (14%)
Frame = +3
Query: 11 EEYQLFEELGKGAFSVVRRCVKVLAGQEYAA-KIINTKKLSARDHQKLEREARICRLLK- 68
++Y+ +G GA+ V + + E+ A K I RE + + L+
Sbjct: 189 QKYEEVAVIGNGAYGTVYKARDLRNQGEFVAMKRIRLNNTEEGMPMMAIREISMLKQLEQ 368
Query: 69 --HPNIVRL----HDSISE-EGHHYLIFDLVTGGELFEDIVAREYYSEADA--------S 113
HPN+VRL H++I++ E L+F+ + D+ Y ++ +
Sbjct: 369 YEHPNVVRLLDVSHNTITDREIRLNLVFEYIE-----HDLAT--YLAKCPSPGLGPDRIK 527
Query: 114 HCIQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGF 173
+ Q+L V H +VHRDLKP+NLL++ K +KLADFGLA + A
Sbjct: 528 DLMLQLLNGVDFLHSNRIVHRDLKPQNLLIS---KDGRLKLADFGLA-RIYSFHMALTTV 695
Query: 174 AGTPGYLSPEVLRKDPYGKPVDLWACGVILYIL---------------------LVGYPP 212
T Y SPEVL + YG VD+W+CG I L ++G PP
Sbjct: 696 VVTLWYRSPEVLMQAEYGTSVDIWSCGCIFAELFTRRALFKGSSEFDQLKKIFEVIGLPP 875
Query: 213 F--WDE--DQHR-LYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPSKRITAAEALK 267
W E HR ++ PE D P+AKDL+ KML +RI++ E+L
Sbjct: 876 AGDWPEGVSVHRNSFRPTPPVPLQTLVPEMD---PQAKDLMEKMLVFKSGRRISSRESLL 1046
Query: 268 HPWI 271
HP++
Sbjct: 1047HPYL 1058
>00300
Length = 2318
Score = 88.6 bits (218), Expect = 5e-18, Method: Compositional matrix adjust.
Identities = 71/277 (25%), Positives = 130/277 (46%), Gaps = 10/277 (3%)
Frame = -1
Query: 4 ITCTRFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLER---E 60
I R +Q ++G+G F V V + G+ A K + K D Q+L E
Sbjct: 1679 INVRRVNFRWQRGNKIGEGQFGKVYTAVNMSTGELMALKEM---KFQPNDLQQLREMCDE 1509
Query: 61 ARICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQIL 120
+I ++H N+V+ + + + + G + E A+ E ++I+
Sbjct: 1508 IKIFEGIQHENLVKYYGVEVHKDEMLMFMEYCDTGTIEE--AAKMGLPEYLIRRYTREIV 1335
Query: 121 EAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQA---WFGFAGTP 177
AV H H+ +VHRD+K N+ L S VKL DFG +++++ + GT
Sbjct: 1334 LAVNHLHENSIVHRDIKGANIFLTSN---GHVKLGDFGCSVKLKSHTTMPGEFHNLVGTT 1164
Query: 178 GYLSPEVLRKDP---YGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQI-KAGAYDFP 233
Y++PEV ++ YG+ D+W+ G ++ + G P+ D D + YQ + K G P
Sbjct: 1163 AYMAPEVFTQNDQGGYGRAADIWSLGCVVIEMATGKRPWHDLDNN--YQIMYKVGIGHKP 990
Query: 234 SPEWDTVTPEAKDLINKMLTINPSKRITAAEALKHPW 270
+ D+++ E K ++ ++ +P++R A++ L H +
Sbjct: 989 AVP-DSLSVEGKHFLDLIMCHDPAQRALASQLLDHTF 882
>21433
Length = 590
Score = 74.3 bits (181), Expect(2) = 1e-16, Method: Compositional matrix adjust.
Identities = 48/142 (33%), Positives = 70/142 (49%), Gaps = 5/142 (3%)
Frame = +2
Query: 116 IQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAG 175
I Q+ A+ +CH V+HRD+KPEN +K+ADFG ++ ++ G
Sbjct: 185 IYQLSSALEYCHYRKVIHRDIKPEN---LLLGLKGDLKIADFGWSVHAPSSRRT--TMCG 349
Query: 176 TPGYLSPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSP 235
T YL PE++ + + VDLW+ GV+ Y LVG PP + SP
Sbjct: 350 TLDYLPPEMVEGKTHDENVDLWSLGVLCYEFLVGTPPL---------RPSPTRPPTPASP 502
Query: 236 EWDT-----VTPEAKDLINKML 252
W + VTP A+DLI+K+L
Sbjct: 503 RWTSGSPSIVTPGARDLISKLL 568
Score = 30.0 bits (66), Expect(2) = 1e-16, Method: Compositional matrix adjust.
Identities = 15/47 (31%), Positives = 26/47 (55%)
Frame = +3
Query: 55 QKLEREARICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDI 101
+L RE I L+H NI+R+ ++ YLI + GEL++++
Sbjct: 3 HQLRREIEIQSHLRHDNILRMFGYFHDKTRVYLILEFAPKGELYKEL 143
>13212
Length = 1067
Score = 79.3 bits (194), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 59/173 (34%), Positives = 88/173 (50%), Gaps = 9/173 (5%)
Frame = -1
Query: 108 SEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQ 167
+EA + ++ A+ H+ V+HRD+K N+LL VKLADFG++ + Q
Sbjct: 986 TEAQICYVCHEMCMALDFLHRHHVIHRDIKAGNVLLTI---DGEVKLADFGVSAKNTQTQ 816
Query: 168 QAWFGFAGTPGYLSPEV-----LRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLY 222
Q F GTP +++PEV L+ PY D+W+ GV L PP +++ H +
Sbjct: 815 QKRDTFIGTPYWMAPEVVLCETLKDTPYDFKADIWSLGVTLIEFAQIEPP--NKEMHPMR 642
Query: 223 QQIKAGAYDFPSPE----WDTVTPEAKDLINKMLTINPSKRITAAEALKHPWI 271
IK D P+ E W + KD I K L +P+ R TAAE L+HP++
Sbjct: 641 VLIKIHKSDPPTLEKPKKWTKL---FKDFIAKCLVKDPNLRPTAAELLEHPFM 492
>13066
Length = 551
Score = 76.3 bits (186), Expect = 3e-14, Method: Compositional matrix adjust.
Identities = 53/166 (31%), Positives = 78/166 (46%), Gaps = 5/166 (3%)
Frame = +3
Query: 40 AAKIINTKKLSARDHQKL-EREARICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELF 98
A KII+ +K +K RE + L HP I+++H + +++ G+L
Sbjct: 63 ACKIIDKEKAPVDFVEKFFPRELDLLTKLDHPYIIQIHSILQRXPKNFIFMRFAERGDLL 242
Query: 99 EDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFG 158
I + E A Q+ A+ + H V HRDLK EN+LL+S VKLADFG
Sbjct: 243 TYIQEVGFVKEKQAKIWFYQMTTALNYLHSYDVAHRDLKCENILLSSHFN---VKLADFG 413
Query: 159 LA---IEVEGEQQAWFGFAGTPGYLSPEVLRKDPYG-KPVDLWACG 200
A I GE+ + G+ Y +PE++ PY K D W+ G
Sbjct: 414 FACACITESGEKYMSRTYCGSAAYAAPEIVYGAPYAPKVADAWSLG 551
>09007
Length = 1440
Score = 71.2 bits (173), Expect = 9e-13, Method: Compositional matrix adjust.
Identities = 59/226 (26%), Positives = 105/226 (46%), Gaps = 13/226 (5%)
Frame = -1
Query: 15 LFEELGKGAFSVVRRCVKVLAGQE---YAAKIINTKKLSARDHQKLEREARICRLLKHPN 71
L + LG+G F VR+ + E A K ++ K+ +D Q+ +E I ++L H N
Sbjct: 867 LSKSLGQGHFGTVRQAIWTAESGEKVQVAVKCLSKDKIH-KDGQEFLKETAIMQMLDHEN 691
Query: 72 IVRLHDSISEEGHH-YLIFDLVTGGELFE---DIVAREYYSEADASHCIQQILEAVLHCH 127
IVR++ + + G L+ +L L E ++ AR +S QQ+ + + +
Sbjct: 690 IVRVYGVVMDNGADIMLVTELAPMRSLLECVKEVSARVDFSVPRLCDFSQQVCDGMSYLE 511
Query: 128 QMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEG-----EQQAWFGFAGTPGYLSP 182
+VHRDL N+LL SK K VK++D G++ + + Q + +P
Sbjct: 510 SKRLVHRDLAARNILLFSKSK---VKISDVGVSGALGAGKEYYQSQQTIHLQNAVAWCAP 340
Query: 183 EVLRKDPYGKPVDLWACGVILYILLV-GYPPFWDEDQHRLYQQIKA 227
E R + D+WA GV+L+ G+ P+ + ++ + + A
Sbjct: 339 ESFRNLCFSSASDVWAFGVLLWEFFTHGFQPWAGLNGQQIMEAVDA 202
>01966
Length = 1735
Score = 70.9 bits (172), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 57/190 (30%), Positives = 86/190 (45%), Gaps = 14/190 (7%)
Frame = -1
Query: 27 VRR---CVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEG 83
VRR C G++ A K I + RE + R L+H NIV L D I E+
Sbjct: 1672 VRRGL*CRHRATGRKLAMKKIRLRGSEDGVPSSAIREIAMLRELRHTNIVCLEDVIMEDE 1493
Query: 84 HHYLIFDLVTG-----------GELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVV 132
+L+F+ ++ G + + + + Y + QI+ + CHQ +V
Sbjct: 1492 RLFLVFEFLSMDLKMYIDKFPEGVVLDRRLVKSY---------VFQIVTGINFCHQRRIV 1340
Query: 133 HRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSPEVLRKDPYGK 192
HRDLKP+NLL+ A+K+ADFG+A +A+ T Y +PE+L P
Sbjct: 1339 HRDLKPQNLLINHT---GAIKIADFGMARTFALPVRAYTHEVVTLWYRAPEIL-MGPQST 1172
Query: 193 PVDLWACGVI 202
P W CG +
Sbjct: 1171 P-PXWTCGAL 1145
Score = 31.6 bits (70), Expect = 0.69, Method: Compositional matrix adjust.
Identities = 32/125 (25%), Positives = 53/125 (42%), Gaps = 25/125 (20%)
Frame = -3
Query: 177 PGYLSPEVLRKDPYGKPVDLWACGVILYILLVGYPPF-WDEDQHRLYQQI---------- 225
PG P K Y PVD+W+ G I +L+ P F D + +L++
Sbjct: 1208 PGPRDPHGASK--YSTPVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQT 1035
Query: 226 -----KAGAYDFPSPEW------DTVT---PEAKDLINKMLTINPSKRITAAEALKHPWI 271
K A++ P W +T+T DLI + L +P++RI+ + L+H +
Sbjct: 1034 WPEFHKLPAFNGMFPLWKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYF 855
Query: 272 SHRST 276
+ T
Sbjct: 854 LNVDT 840
>31885
Length = 529
Score = 70.1 bits (170), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 46/152 (30%), Positives = 76/152 (50%), Gaps = 5/152 (3%)
Frame = -2
Query: 67 LKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHC 126
L HP +V L + +E +++ DL GG+L + + E + Q+ + +
Sbjct: 501 LDHPFLVNLWYAFQDEEDLFMVVDLFLGGDLRYHMQQEVSFREDCVKFYLCQLALVLDYL 322
Query: 127 HQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSPEVL- 185
+VHRD+KP+N+LL + + DF +A ++E ++ A +GT Y++PEV
Sbjct: 321 RSQKIVHRDIKPDNILLDEQ---GHCHVTDFNIATQLEDDELA-TSTSGTRPYMAPEVYG 154
Query: 186 ----RKDPYGKPVDLWACGVILYILLVGYPPF 213
+ YG PVD W+ GV L+ LL PF
Sbjct: 153 VAINERRGYGFPVDWWSLGVSLFELLKKRRPF 58
>00392
Length = 668
Score = 69.3 bits (168), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 55/214 (25%), Positives = 104/214 (48%), Gaps = 8/214 (3%)
Frame = +3
Query: 44 INTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGHH-----YLIFDLVTGGELF 98
+ KK + + Q+ + EA + + L+HPNIVR D E H L+ +L+T G L
Sbjct: 33 LQDKKWNKAERQRFKEEAEMLKELQHPNIVRFFDYWEEHNHRNRKVIILVTELMTSGTLK 212
Query: 99 EDIVAREYYSEADASHCIQQILEAV--LHCHQMGVVHRDLKPENLLLASKLKGAAVKLAD 156
+ + + + +Q+L+ + LH V+HRDLK +N+ + +VK+ D
Sbjct: 213 TYLKRFKKPNVKILKNWCRQVLKGLYFLHTRTPPVIHRDLKCDNIFITG--PTGSVKIGD 386
Query: 157 FGLAIEVEGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWD- 215
GLA Q GTP +++PE + ++ Y + VD++A G+ + + P+ +
Sbjct: 387 LGLA--TLKNQSFAKSVIGTPEFMAPE-MYEEHYDEAVDVYAFGMCMLEMASSEYPYSEC 557
Query: 216 EDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLIN 249
+ ++Y+++ +G P E +D+I+
Sbjct: 558 SNAAQIYKRVTSGV--LPEALDKVAITEIRDIIH 653
>28638
Length = 1458
Score = 63.9 bits (154), Expect(2) = 4e-12, Method: Compositional matrix adjust.
Identities = 37/99 (37%), Positives = 57/99 (57%), Gaps = 2/99 (2%)
Frame = -1
Query: 117 QQILEAVLHCH--QMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFA 174
QQ+ A+L +M ++H DLKPEN+LL + K +A+K+ DFG + ++ Q + +
Sbjct: 816 QQLCTALLFLATPEMNIIHCDLKPENILLCNP-KRSAIKIVDFGSSCQLG---QRIYQYI 649
Query: 175 GTPGYLSPEVLRKDPYGKPVDLWACGVILYILLVGYPPF 213
+ Y SPEVL PY +D+W+ G IL + G PP
Sbjct: 648 QSRFYRSPEVLLGVPYDLAIDMWSLGCILVEMHTGEPPL 532
Score = 25.4 bits (54), Expect(2) = 4e-12, Method: Compositional matrix adjust.
Identities = 22/92 (23%), Positives = 42/92 (45%), Gaps = 6/92 (6%)
Frame = -3
Query: 8 RFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLL 67
++ + Y++ +GKG+F V + ++ A KII KK + + E ++ L+
Sbjct: 1156 KWLDRYEIDSLIGKGSFGQVVKAYDHGDQEQVAIKIIKNKKPFL---NQAQIEVKLLELM 986
Query: 68 KHPN------IVRLHDSISEEGHHYLIFDLVT 93
+ IVRL H L+F+L++
Sbjct: 985 NRHDADNXYYIVRLKRHFMFRNHLCLVFELLS 890
>00486
Length = 797
Score = 68.2 bits (165), Expect = 7e-12, Method: Compositional matrix adjust.
Identities = 35/102 (34%), Positives = 56/102 (54%)
Frame = -2
Query: 173 FAGTPGYLSPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDF 232
F GT Y++PE+L + +GK VD W+ G ++Y +L G PPF E++ + +I G +
Sbjct: 778 FCGTIEYMAPEILTRTGHGKAVDWWSLGALMYDMLTGSPPFTAENRKKTIDKILKGKLNL 599
Query: 233 PSPEWDTVTPEAKDLINKMLTINPSKRITAAEALKHPWISHR 274
P +T EA+ LI K+L NP++R+ P H+
Sbjct: 598 PP----YLTNEARGLIKKLLRKNPAERLGGGHDDSGPIKDHQ 485
>27405
Length = 532
Score = 67.8 bits (164), Expect = 9e-12, Method: Compositional matrix adjust.
Identities = 49/170 (28%), Positives = 79/170 (46%), Gaps = 5/170 (2%)
Frame = -3
Query: 23 AFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLL-----KHPNIVRLHD 77
F V C K G+ YA K ++ K++ + + L RI L P IV +
Sbjct: 530 GFGEVYGCRKADTGKMYAMKCLDKKRIKMKGGETLALNERIMLSLVSTGEGSPFIVCMTY 351
Query: 78 SISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLK 137
+ I DL+ GG+L + ++E + +++ + H H VV+RDLK
Sbjct: 350 AFQTPEKLCFILDLMNGGDLHYHLSQHGVFTEKEVRFYAAEVMLGLEHMHSRFVVYRDLK 171
Query: 138 PENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSPEVLRK 187
P N+LL + V+++D GLA + ++ GT GY++PEVL K
Sbjct: 170 PANILLD---ENGHVRISDLGLACDF--SKKKPHASVGTHGYMAPEVLMK 36
>19761
Length = 473
Score = 67.4 bits (163), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 44/130 (33%), Positives = 65/130 (50%)
Frame = -3
Query: 124 LHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSPE 183
+H H ++HRDLKP+N+ + K V+L D GLA ++ G GT YLSPE
Sbjct: 375 MHTHTPVILHRDLKPQNIYVTEK---GDVRLGDLGLARKLTGPADFATSQVGTIMYLSPE 205
Query: 184 VLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPE 243
+L + PY D+W+ G + Y + G + L Q+ G P P D + E
Sbjct: 204 ILSQQPYNSKSDIWSLGCVFYD-ITGKKGSDEMGVMFLLVQVMGGR-KLPLP--DHYSQE 37
Query: 244 AKDLINKMLT 253
+D I++MLT
Sbjct: 36 FRDTISRMLT 7
>01718
Length = 959
Score = 67.0 bits (162), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 54/192 (28%), Positives = 96/192 (50%), Gaps = 5/192 (2%)
Frame = +3
Query: 17 EELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLH 76
E++G G FS V + + GQ A K+ NT +++ H L RE ++ L+H NI+R
Sbjct: 165 EKIGAGFFSEVFKVTHRITGQVMALKM-NT--MTSNRHNML-REVQLLNRLQHANILRFM 332
Query: 77 DSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQIL---EAVLHCHQMGVVH 133
EG + + + + G L + + ++ E + IQ L + + H +H
Sbjct: 333 GVCVHEGQLHALTEYIPSGNLEQLLEKKD--EELPWTQRIQLTLGLARGLDYLHSTRFIH 506
Query: 134 RDLKPENLLLASKLK-GAAVKLADFGLAIEV-EGEQQAWFGFAGTPGYLSPEVLRKDPYG 191
RDL +N+L+ + G +ADFGLA ++ + + G+P +++PEVL Y
Sbjct: 507 RDLTSKNILIRREDNHGYHAVIADFGLATKIPDPLDKEKLPTVGSPYWMAPEVLNGHFYN 686
Query: 192 KPVDLWACGVIL 203
+ DL++ G+I+
Sbjct: 687 ERADLFSVGIIM 722
>38560
Length = 479
Score = 65.5 bits (158), Expect = 5e-11, Method: Compositional matrix adjust.
Identities = 44/121 (36%), Positives = 61/121 (50%), Gaps = 5/121 (4%)
Frame = -3
Query: 175 GTPGYLSPEVLRKDPY-GKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFP 233
G+P Y +PE++ Y G D+W+ GV+LY LL GY PF DE L Q+ + +
Sbjct: 399 GSPAYAAPELISGLEYLGSEADIWSMGVLLYALLCGYLPFDDEKXSHL*QKNQKRKDEV- 223
Query: 234 SPEWDTVTPEAKDLINKMLTINPSKRITAAEALKHPWISHRSTV----ASCMHRQETVDC 289
PEW ++ + L+ ML +PS RIT L H W++ V AS R DC
Sbjct: 222 -PEW--LSEDTTKLLEGMLQTDPSHRITIRRLLDHHWLNQGFNVPVEWASKYKRTLDEDC 52
Query: 290 L 290
L
Sbjct: 51 L 49
>18921
Length = 697
Score = 64.7 bits (156), Expect = 9e-11, Method: Compositional matrix adjust.
Identities = 47/201 (23%), Positives = 95/201 (47%), Gaps = 1/201 (0%)
Frame = +2
Query: 13 YQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNI 72
+ + +LG+G++ V + + GQ A K + D Q++ +E I + I
Sbjct: 35 FDILGKLGEGSYGSVFKSLHKETGQVLAIKQVPVDT----DLQEIIKEISIMQQCDSKYI 202
Query: 73 VRLHDSISEEGHHYLIFDLVTGGELFEDIVAR-EYYSEADASHCIQQILEAVLHCHQMGV 131
V+ + S + +++ + G + + + R + E + + + L+ + + H
Sbjct: 203 VKYYGSYFKNTDLWIVMEYCGAGSVSDIMRLRNKTLVEREIATILYYTLKGLXYLHSRRK 382
Query: 132 VHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSPEVLRKDPYG 191
+HRD+K N+LL ++ KLADFG+A ++ GTP +++PEV+++ Y
Sbjct: 383 IHRDIKAGNILLNNE---GHAKLADFGVAGQLTDTMAKRNTVIGTPYWMAPEVIQEIGYD 553
Query: 192 KPVDLWACGVILYILLVGYPP 212
D+W+ G+ + G PP
Sbjct: 554 CVADIWSLGITALEMAEGKPP 616
>06405
Length = 1965
Score = 63.5 bits (153), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 56/221 (25%), Positives = 96/221 (43%), Gaps = 4/221 (1%)
Frame = +1
Query: 12 EYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPN 71
E + LG G + V + + A K + ++ D EA I + +KHPN
Sbjct: 262 EIAMKHRLGGGQYGDVYEAMWKRYNKIVAVKTLKEDTMALND---FLEEAAIMKEMKHPN 432
Query: 72 IVRLHDSISEEGHHYLIFDLVTGGELFEDIVA--REYYSEADASHCIQQILEAVLHCHQM 129
+V+L + E Y++ + + G L + + + RE + QI + +
Sbjct: 433 LVQLLGVCTREPPFYIVTEFMPHGNLLDYLRSSTREENGPTALMYMATQIASGMAYLETK 612
Query: 130 GVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQ-QAWFGFAGTPGYLSPEVLRKD 188
+HRDL N L+A VK+ADFGLA ++ + A G + +PE L +
Sbjct: 613 NFIHRDLAARNCLVAD---SNMVKVADFGLARLMKDDTYTAHIGAKFPIKWTAPEGLAFN 783
Query: 189 PYGKPVDLWACGVILYILLV-GYPPFWDEDQHRLYQQIKAG 228
+ D+WA GV+L+ L G P+ + +Y ++ G
Sbjct: 784 RFSTRSDIWAFGVLLWELATYGMSPYPGVELTEVYHLLERG 906
>21808
Length = 1011
Score = 63.2 bits (152), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 51/195 (26%), Positives = 91/195 (46%), Gaps = 3/195 (1%)
Frame = +1
Query: 44 INTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVA 103
I T K D + EA+I + L+HP +++L+ +++ ++I +L+ G L E +
Sbjct: 34 IKTLKSGTMDPKDFLAEAQIMKKLRHPKLIQLYAVCTQDDPIFIITELMKNGSLLEFLQG 213
Query: 104 REYYSEADASHCI-QQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIE 162
+ + A I QI + + +HRDL N+L++ VK+ADFGLA
Sbjct: 214 KGRVLKLPALIDIGAQIACGMAYLESQNYIHRDLAARNILVSDN---NTVKIADFGLARV 384
Query: 163 V-EGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDLWACGVILY-ILLVGYPPFWDEDQHR 220
+ E E +A G + +PE + + D+W+ G++L + G P+
Sbjct: 385 IKEDEYEARVGARFPIKWTAPEAANYNRFTIKSDVWSFGILLTETVTYGRVPYPGMTNAE 564
Query: 221 LYQQIKAGAYDFPSP 235
+ Q++ G Y P P
Sbjct: 565 VLHQVEHG-YRMPCP 606
>26560
Length = 398
Score = 63.2 bits (152), Expect = 2e-10, Method: Composition-based stats.
Identities = 38/113 (33%), Positives = 61/113 (53%), Gaps = 1/113 (0%)
Frame = -1
Query: 107 YSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGE 166
++E + +++ + H H VV+RDLKP N+LL + V+++D GLA + +
Sbjct: 365 FTEKEVRFYAAEVMLGLEHMHSRFVVYRDLKPANILLD---ENGHVRISDLGLACDFSKK 195
Query: 167 QQAWFGFAGTPGYLSPEVLRK-DPYGKPVDLWACGVILYILLVGYPPFWDEDQ 218
+ GT GY++PEVL K Y D ++ G +LY LL G+ PF +Q
Sbjct: 194 RP--HASVGTHGYMAPEVLMKGQSYDSSADWFSFGCMLYKLLKGHSPFRQHNQ 42
>29581
Length = 1278
Score = 62.8 bits (151), Expect = 3e-10, Method: Compositional matrix adjust.
Identities = 65/243 (26%), Positives = 106/243 (43%), Gaps = 35/243 (14%)
Frame = -2
Query: 67 LKHPNIVRLHDSISEEGHHYLIF-------DLVTGGELFEDIVAREYYSEADASHCIQQI 119
L+H NIV+L + + + L DL + L +++ A +SE+ + Q+
Sbjct: 1184 LRHQNIVQLQEVVVGKSLDSLFLVMEYCEQDLAS---LLDNMPAP--FSESQVKCIVLQL 1020
Query: 120 LEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGY 179
L+ + + H+ ++HRDLK NLL+ K VK+ADFGLA Q+ T Y
Sbjct: 1019 LKGLRYLHEAFIIHRDLKVSNLLMTDK---GCVKIADFGLARNYGKPQKPMTPKVVTLWY 849
Query: 180 LSPEVL-RKDPYGKPVDLWACGVILYILLVGYPPFW----DEDQHRLYQQ--------IK 226
+PE+L + +D+W+ G IL LL G+ P D Q L + I
Sbjct: 848 RAPELLFGSKTHSTAIDMWSAGCILGELL-GHKPLMPGRSDLQQIELIMELLGTPNDTIW 672
Query: 227 AGAYDFPSPEWDTVTPEAKD---------------LINKMLTINPSKRITAAEALKHPWI 271
G P+ E T+ + + L+N + +P KR TA + L+H +
Sbjct: 671 PGFSQLPAFEQFTLKKQPYNNLRHTFPWLSESGIRLLNGLFMYHPQKRATAEDCLEHSYF 492
Query: 272 SHR 274
+
Sbjct: 491 KEQ 483
>21418
Length = 831
Score = 62.4 bits (150), Expect = 4e-10, Method: Compositional matrix adjust.
Identities = 25/57 (43%), Positives = 38/57 (66%)
Frame = +2
Query: 221 LYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPSKRITAAEALKHPWISHRSTV 277
+ ++I++G YDFP PEW V+ AKDLI ML ++PSKR+ + L++ WI+ V
Sbjct: 2 MKKRIRSGQYDFPDPEWTNVSQAAKDLIKGMLNVDPSKRLCIEDVLRNKWIAQYDAV 172
>36002
Length = 253
Score = 60.8 bits (146), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 26/56 (46%), Positives = 36/56 (64%)
Frame = +1
Query: 218 QHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPSKRITAAEALKHPWISH 273
Q L+ +I+ G Y FPS EW ++ AKDLI +L P KR +AA+ LKHPW+ +
Sbjct: 49 QELLFNRIQDGNYFFPSMEWSAISSSAKDLIRHLLVREPRKRYSAADVLKHPWVCN 216
>20152
Length = 445
Score = 60.8 bits (146), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 34/92 (36%), Positives = 48/92 (52%), Gaps = 1/92 (1%)
Frame = +1
Query: 182 PEVLRKDPYGKP-VDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTV 240
PE+L D Y P VD+W+ GVILY+L+VG PF + + I Y P +
Sbjct: 1 PEILLGDSYDAPAVDVWSLGVILYMLVVGEAPFQEANDSETLTMIMDCRYQIPP----HI 168
Query: 241 TPEAKDLINKMLTINPSKRITAAEALKHPWIS 272
+ + +DLI KML P R + L HPW++
Sbjct: 169 SHKCQDLIEKMLQREPVDRASLPHILAHPWLN 264
>12786
Length = 460
Score = 60.5 bits (145), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 38/119 (31%), Positives = 57/119 (47%), Gaps = 22/119 (18%)
Frame = -3
Query: 117 QQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWF--GFA 174
+++L AV H GV+H DLKP N +L + +KL DFG+A ++ ++ +
Sbjct: 389 REMLRAVKALHNEGVIHSDLKPANFMLVA----GNLKLIDFGIANTLQQDKTSVLKDSRV 222
Query: 175 GTPGYLSPEVL-----------------RKDP---YGKPVDLWACGVILYILLVGYPPF 213
GTP Y+SPE + R P G D+W+ G ILY ++ G PF
Sbjct: 221 GTPSYMSPEAIMAACDDSADDSMEEDGHRTKPKYKVGVRSDVWSLGCILYNMVYGRTPF 45
>29590
Length = 320
Score = 45.1 bits (105), Expect(2) = 2e-09, Method: Composition-based stats.
Identities = 17/39 (43%), Positives = 25/39 (64%)
Frame = +3
Query: 175 GTPGYLSPEVLRKDPYGKPVDLWACGVILYILLVGYPPF 213
GTP Y++PEVL +P D+W+ GV+ Y++L PF
Sbjct: 60 GTPDYVAPEVLDYEPLSIQTDMWSLGVLSYVMLTACSPF 176
Score = 35.0 bits (79), Expect(2) = 2e-09, Method: Composition-based stats.
Identities = 15/46 (32%), Positives = 24/46 (52%)
Frame = +2
Query: 216 EDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPSKRIT 261
++Q + I DFP + ++P AKD I K+L +P R+T
Sbjct: 182 DNQQETFCNISQVKLDFPDDLFSHISPHAKDFIKKLLVKDPRHRMT 319
>19094
Length = 898
Score = 49.7 bits (117), Expect(2) = 6e-09, Method: Compositional matrix adjust.
Identities = 27/93 (29%), Positives = 50/93 (53%)
Frame = +1
Query: 109 EADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQ 168
E + + + L+ + + H +HRD+K N+LL ++ KLADFG+A ++
Sbjct: 55 EREIATILYYTLKGL*YLHSRRKIHRDIKAGNILLNNE---GHAKLADFGVAGQLTDTMA 225
Query: 169 AWFGFAGTPGYLSPEVLRKDPYGKPVDLWACGV 201
GTP +++PEV+++ Y D+W+ G+
Sbjct: 226 KRNTVIGTPYWMAPEVIQEIGYDCVADIWSLGI 324
Score = 28.5 bits (62), Expect(2) = 6e-09, Method: Compositional matrix adjust.
Identities = 21/66 (31%), Positives = 29/66 (43%), Gaps = 3/66 (4%)
Frame = +3
Query: 209 GYPPFWDEDQHRLYQQIKAGAYDFPSPEW---DTVTPEAKDLINKMLTINPSKRITAAEA 265
G PP+ D R I P P + D + E D ++K L NP R TA +
Sbjct: 345 GKPPYGDIHPMRAIFMIPTK----PPPSFRQPDKWSTEFIDFVSKCLVKNPENRATAVDL 512
Query: 266 LKHPWI 271
L+H +I
Sbjct: 513 LQHDFI 530
>01756
Length = 1858
Score = 58.5 bits (140), Expect = 6e-09, Method: Compositional matrix adjust.
Identities = 56/214 (26%), Positives = 95/214 (44%), Gaps = 22/214 (10%)
Frame = -3
Query: 12 EYQLFEELGKGAFSVV--RRCVKVLAGQEYAAKIINTKKLSARDHQK-----LEREARIC 64
+Y+ ++G+G F V RC K +++ KK+ + ++ RE +I
Sbjct: 1739 KYEKLAKIGQGTFGEVFKARCKKT-------KQVVAMKKVLMDNEKEGFPITALREIKIL 1581
Query: 65 RLLKHPNIVRLHDSISEEG--------HHYLIFDLV---TGGELFEDIVAREYYSEADAS 113
+LL H N+V L + S + YL+F+ G L V ++ +
Sbjct: 1580 QLLNHENVVDLIEICSTKATSANRYKSMFYLVFEFCEHDLAGLLSNMSVV---FNLPEIK 1410
Query: 114 HCIQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGL--AIEVEGEQ-QAW 170
++Q++ + + H+ ++HRD+K N+L+ K +KLADFGL A V Q +
Sbjct: 1409 EVMKQLMNGLYYIHRNKILHRDMKAANILIT---KQGVLKLADFGLARAFSVNLRQPNRY 1239
Query: 171 FGFAGTPGYLSPEVLRKD-PYGKPVDLWACGVIL 203
T Y PE+L D Y +D W G I+
Sbjct: 1238 TNRVVTLWYRPPELLLGDRNYSTAIDQWGAGCIM 1137
>04591
Length = 1117
Score = 58.2 bits (139), Expect = 7e-09, Method: Compositional matrix adjust.
Identities = 48/157 (30%), Positives = 77/157 (49%), Gaps = 12/157 (7%)
Frame = -2
Query: 59 REARICRLLKHPNIVRLHDSI-SEEGHH-------YLIF---DLVTGGELFEDIVAREYY 107
RE +I + L+H N+V+L + ++ G + YLIF D G L R +
Sbjct: 1074 REIKILQQLEHENVVQLQEICHTQAGPYNRYKSTFYLIFEYCDYDLAGLLNN---LRVKF 904
Query: 108 SEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQ 167
S AD + + Q+L + + H ++HRD+K N+LL + +KLADFGL+ +
Sbjct: 903 SLADKKNLMSQLLNGLFYIHTKQILHRDIKAANILLT---RDGVLKLADFGLS-RPWVKS 736
Query: 168 QAWFGFAGTPGYLSPEVLRKD-PYGKPVDLWACGVIL 203
+ T Y PE+L + YG +D+W G I+
Sbjct: 735 KRLTNRVVTLWYRPPELLLGEREYGPEIDMWGVGCIM 625
>27546
Length = 426
Score = 56.2 bits (134), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 38/103 (36%), Positives = 53/103 (51%), Gaps = 1/103 (0%)
Frame = -1
Query: 59 REARICRLLKHPNIVRLHDSISEEGHHYLIF-DLVTGGELFEDIVAREYYSEADASHCIQ 117
RE I L HPNI+++H SI + G IF G++ I EA
Sbjct: 333 RELEILTRLDHPNIIQIH-SILQRGPKIFIFMRYAEKGDMLSHIKKTGPIDEAQTKVWFF 157
Query: 118 QILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLA 160
Q+ +A+ + H + HRDLK EN+LL+ +L VK+ADFG A
Sbjct: 156 QMAKALQYLHSHDIAHRDLKCENILLSKRLN---VKIADFGFA 37
>18663
Length = 600
Score = 55.5 bits (132), Expect = 5e-08, Method: Compositional matrix adjust.
Identities = 34/97 (35%), Positives = 51/97 (52%), Gaps = 9/97 (9%)
Frame = +2
Query: 173 FAGTPGYLSPEVLRKDPYGKPVDLWACGVILYILLVGYPPF------WDEDQHR---LYQ 223
F GTP Y++PE+LR + YG VD WA GV+LY +L G PF + DQ+ L+Q
Sbjct: 8 FCGTPNYIAPEILRGEDYGFSVDWWALGVLLYEMLAGRSPFDIAGASENPDQNTEDYLFQ 187
Query: 224 QIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPSKRI 260
I P +++ +A ++ L NP+ R+
Sbjct: 188 VILEKTIRIPR----SLSVKAASVLKGFLNKNPADRL 286
>11185
Length = 473
Score = 55.5 bits (132), Expect = 5e-08, Method: Compositional matrix adjust.
Identities = 45/167 (26%), Positives = 75/167 (44%), Gaps = 23/167 (13%)
Frame = +1
Query: 125 HCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGE--QQAWFGFA-------- 174
+ H +G++ DL+P +LL + +K ADFGL+ +VEGE ++ +F FA
Sbjct: 46 YIHSLGILFHDLRPSKVLLDTS---GVLKFADFGLS-KVEGENLEELFFKFAEAGDQWNI 213
Query: 175 -------------GTPGYLSPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRL 221
G+P Y++PEV + DLWA G + Y + G RL
Sbjct: 214 QSAEEMMKQVPTSGSPTYMAPEVFQGAEPSIMSDLWALGCVFYEMFSG---------SRL 366
Query: 222 YQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPSKRITAAEALKH 268
+ PSPE+ +L+ +L + ++R++ A +KH
Sbjct: 367 SAK--------PSPEF-------LNLLESLLQKDSTRRLSWASLVKH 462
>20655
Length = 1181
Score = 55.1 bits (131), Expect = 7e-08, Method: Compositional matrix adjust.
Identities = 21/57 (36%), Positives = 35/57 (61%)
Frame = +2
Query: 221 LYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPSKRITAAEALKHPWISHRSTV 277
+ ++I+ G Y+FP PEW V+ +AKDLI ML +P KR+ + + W++ + V
Sbjct: 2 MKKRIRNGQYEFPKPEWSRVSQDAKDLIRGMLCTDPDKRLNIKQVMASKWVADNTMV 172
>04138
Length = 800
Score = 54.7 bits (130), Expect = 8e-08, Method: Compositional matrix adjust.
Identities = 55/182 (30%), Positives = 77/182 (42%), Gaps = 34/182 (18%)
Frame = +1
Query: 121 EAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGL--AIEVEGEQ-QAWFGFAGTP 177
E + + H+ ++HRD+K N+L+ K +KLADFGL A V Q + T
Sbjct: 46 ERLYYIHRNKILHRDMKAANILIT---KQGVLKLADFGLARAFSVNLRQPNRYTNRVVTL 216
Query: 178 GYLSPEVLRKD-PYGKPVDLWACGVI---------------------LYILLVG--YPPF 213
Y PE+L D Y +D W G I L L G P
Sbjct: 217 WYRPPELLLGDRNYSTAIDQWGAGCIMAEMWTRNPIMQGTTEQNQLTLITQLCGSITPEV 396
Query: 214 W-DEDQHRLYQQIK----AGAYDFPSPEWDTVT--PEAKDLINKMLTINPSKRITAAEAL 266
W Q +Y QIK AG + + + P DL ++L ++PS+RI+A EAL
Sbjct: 397 WPGVTQLSMYHQIKGALAAGRKNIIRDRFARILKDPYGLDLFERLLKMDPSQRISADEAL 576
Query: 267 KH 268
H
Sbjct: 577 NH 582
>27274
Length = 396
Score = 53.1 bits (126), Expect = 2e-07, Method: Composition-based stats.
Identities = 29/98 (29%), Positives = 52/98 (53%), Gaps = 8/98 (8%)
Frame = -1
Query: 183 EVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHR--------LYQQIKAGAYDFPS 234
E+LR +G VD+W+ G++L+ LL G+ PF E R +Y QI G+
Sbjct: 375 ELLRGQQHGPTVDMWSLGILLHELLSGHVPFEPERGSRQMARNMMAVYAQIIRGS-SRDV 199
Query: 235 PEWDTVTPEAKDLINKMLTINPSKRITAAEALKHPWIS 272
+ ++ D + +++ + +KR+T+ +A HPWI+
Sbjct: 198 CDGLALSTHGADFLRRLVQLEDTKRLTSQQAFSHPWIA 85
>31120
Length = 439
Score = 52.8 bits (125), Expect = 3e-07, Method: Composition-based stats.
Identities = 30/90 (33%), Positives = 47/90 (52%), Gaps = 1/90 (1%)
Frame = +1
Query: 183 EVLRKDPYG-KPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVT 241
EV+ PY K D W+ GVIL+I+L G PF D + ++L + ++ Y F D V+
Sbjct: 1 EVVCGVPYDPKMADAWSLGVILFIMLNGKMPFDDSNLNKLLEDQRSKKYSFRRKLQDLVS 180
Query: 242 PEAKDLINKMLTINPSKRITAAEALKHPWI 271
P A+ ++ +L N + R E L W+
Sbjct: 181 PNARSTVSVLLEPNSAMRWDLNEVLNCQWL 270
>02638
Length = 1490
Score = 52.0 bits (123), Expect = 6e-07, Method: Compositional matrix adjust.
Identities = 29/102 (28%), Positives = 52/102 (50%), Gaps = 1/102 (0%)
Frame = +1
Query: 175 GTPGYLSPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDED-QHRLYQQIKAGAYDFP 233
GT +++PEVLR + YG+ D+W+ G ++ + PP+ D + L K + P
Sbjct: 22 GTIAFMAPEVLRGESYGRACDVWSVGCVMIEMCTCRPPWNSHDISNHLALIFKIASSVDP 201
Query: 234 SPEWDTVTPEAKDLINKMLTINPSKRITAAEALKHPWISHRS 275
P + ++P +DL+ + L + R +A + L HP + S
Sbjct: 202 PPIPENMSPPVRDLMLRCLEQDSDFRPSAKDLLMHPLFTKYS 327
>32000
Length = 644
Score = 51.2 bits (121), Expect = 9e-07, Method: Compositional matrix adjust.
Identities = 44/148 (29%), Positives = 74/148 (50%), Gaps = 25/148 (16%)
Frame = -1
Query: 150 AAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSPEVLRK-DPYGKPVDLWACGVILYILLV 208
A +K+ADFGLA + + T Y +PE+L Y PVD+W+ G I ++
Sbjct: 578 AKMKIADFGLARVFGLPVRTYTHEVITLWYRAPEILLGCRFYSVPVDIWSLGCIFVEMMT 399
Query: 209 G---YPPFWDEDQ-HRLY-------QQIKAGAYDFPS-----PEW-----DTVTPEAK-- 245
+P + DQ +R++ +++ G P P+W +TV +K
Sbjct: 398 RRALFPGDSEIDQLYRIFRTLGTPDEKVWPGVSKLPDYKPTFPKWPLKNLETVVSLSKVG 219
Query: 246 -DLINKMLTINPSKRITAAEALKHPWIS 272
DL+ +MLT NP++RI+A A++HP+ +
Sbjct: 218 LDLLKRMLTYNPNRRISARSAMRHPYFN 135
>17300
Length = 480
Score = 51.2 bits (121), Expect = 9e-07, Method: Compositional matrix adjust.
Identities = 33/113 (29%), Positives = 56/113 (49%), Gaps = 7/113 (6%)
Frame = +1
Query: 128 QMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPG------YLS 181
MG VHRDL N+L+ L K+ADFGL+ E+E + G T G + +
Sbjct: 28 DMGYVHRDLAARNILVNEIL---VCKVADFGLSREIESDTTE--GAYTTKGGKIPVRWTA 192
Query: 182 PEVLRKDPYGKPVDLWACGVILY-ILLVGYPPFWDEDQHRLYQQIKAGAYDFP 233
PE + + D+W+ GV+++ ++ G P+W+ + + ++ G Y P
Sbjct: 193 PEAIAYRKFTSASDVWSFGVVMWEVMSYGERPYWNWSNQDVIKAVEKG-YRLP 348
>19301
Length = 712
Score = 51.2 bits (121), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 41/145 (28%), Positives = 65/145 (44%)
Frame = +2
Query: 16 FEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRL 75
E LG GA V + L +E A K + K E + R R L HPNI+
Sbjct: 320 LEWLGSGAQGAV--FLGKLCAEEVAVKKVRDIK---------ETDIRNLRKLNHPNIISF 466
Query: 76 HDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRD 135
++ + +I + G+L+E + + A +QI + + H ++HRD
Sbjct: 467 KGVCTQAPCYCIIMEYCPYGQLYEVLRDGKEIPPALVLDWSKQIASGMNYLHSHKIIHRD 646
Query: 136 LKPENLLLASKLKGAAVKLADFGLA 160
LK N+L+A K VK++DFG +
Sbjct: 647 LKSPNVLVA---KNDVVKISDFGTS 712
>04852
Length = 1462
Score = 50.8 bits (120), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 50/218 (22%), Positives = 92/218 (42%), Gaps = 30/218 (13%)
Frame = +1
Query: 49 LSARDHQKLEREARICRLLK----HPNIVRLHDSISEEGHHYLIFDLVTGGEL------- 97
++A + Q +E ++ + +K H NIV ++ G ++I + G L
Sbjct: 55 VTAVEEQDFVQELQVMKAVKKMGSHINIVNFLGCCTQGGPLWVIVEFAKNGNLRDFLESC 234
Query: 98 ------FEDIVARE---YYSEADASHCIQ---------QILEAVLHCHQMGVVHRDLKPE 139
+ V+ + +Y++ H I+ QI + +HRDL
Sbjct: 235 RDGINGYGKFVSPQDPGWYTKTPGGHVIRRKNLLSYAFQIARGMEFLASRKCIHRDLAAR 414
Query: 140 NLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDLWAC 199
N+L+ + +K+ADFGL+ + ++ G +++PE L Y D+W+
Sbjct: 415 NVLVTEE---HVLKIADFGLSRTGDYYKKRSGGRLPVK-WMAPEALFDMRYTTKSDVWSF 582
Query: 200 GVILY-ILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPE 236
GV+L+ I +G P+ LY ++ AY P PE
Sbjct: 583 GVVLWEIFSLGGMPYASIPNEELYSKLLDDAYRMPRPE 696
>03508
Length = 1463
Score = 50.4 bits (119), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 44/198 (22%), Positives = 90/198 (45%), Gaps = 5/198 (2%)
Frame = +1
Query: 11 EEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLKHP 70
++YQ+ +LG+G +S V + V + K + + + + L
Sbjct: 589 DDYQIVRKLGRGKYSEVFEAINVTNNE----KCVIKILKPVKKKKIKREIKILENLRGGT 756
Query: 71 NIVRL----HDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHC 126
N++ L D +S LIF+ V + + + +++ D + ++++A+ C
Sbjct: 757 NVITLLAIVKDPVSRTPA--LIFEHVNNTDFKQ---LYQTFTDYDIRFYLYELMKALDFC 921
Query: 127 HQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSPEVLR 186
H MG++HRD+KP N+++ + K ++L D+GLA E + + + PE+L
Sbjct: 922 HSMGIMHRDVKPHNVMIDHENK--KLRLIDWGLA-EFYHPGMEYNVRVASRYFKGPELLL 1092
Query: 187 K-DPYGKPVDLWACGVIL 203
Y +D+W+ G +
Sbjct: 1093DYQMYDYSLDMWSLGCMF 1146
Score = 36.6 bits (83), Expect = 0.022, Method: Compositional matrix adjust.
Identities = 13/32 (40%), Positives = 24/32 (75%)
Frame = +2
Query: 240 VTPEAKDLINKMLTINPSKRITAAEALKHPWI 271
++PEA D ++K+L + ++R+TA EA+ HP+
Sbjct: 1358 ISPEALDFLDKLLRYDHNERLTAREAMDHPYF 1453
>28157
Length = 400
Score = 49.7 bits (117), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 38/133 (28%), Positives = 67/133 (50%), Gaps = 6/133 (4%)
Frame = +3
Query: 37 QEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGE 96
++ A K I +++ Q+L++ +R+ HPNIV L+ + + L+ + GG
Sbjct: 3 KDVAVKRIESEQEKKSFMQELKQLSRV----SHPNIVCLYGACRDHPV-CLVMEYAEGGS 167
Query: 97 LFEDIVAREYYSEADASHCIQQILEAVL---HCHQM---GVVHRDLKPENLLLASKLKGA 150
L+ + + A+H + +L+ L + H M ++HRDLKP NLLL G
Sbjct: 168 LYNVLHGSGPQPQYTAAHAMNWLLQCALGVEYLHGMKPKALIHRDLKPPNLLLIQ--CGT 341
Query: 151 AVKLADFGLAIEV 163
+K+ DFG A ++
Sbjct: 342 KLKICDFGTACDI 380
>17722
Length = 680
Score = 48.9 bits (115), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 24/72 (33%), Positives = 40/72 (55%)
Frame = -3
Query: 194 VDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLT 253
VD W GV++Y ++ G PF++ D L++ I FP ++ EAK L++ +L
Sbjct: 678 VDWWGTGVVMYEMMCGRLPFYNRDHDVLFELILLQNVKFPR----NLSEEAKTLLSGLLA 511
Query: 254 INPSKRITAAEA 265
NP +R+ +EA
Sbjct: 510 KNPKRRLGGSEA 475
>14116
Length = 1017
Score = 48.1 bits (113), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 51/204 (25%), Positives = 88/204 (43%), Gaps = 13/204 (6%)
Frame = -1
Query: 17 EELGKGAFSVVRRCVKVLAGQE----YAAKIINTKKLSARDHQKLEREARICRLLKHPNI 72
EE+GKG F V+R L Q+ A K ++ + Q +EA I + H N+
Sbjct: 618 EEIGKGNFGCVKRGFLTLPEQKGDILVAVKTLHNNNPREIELQSFLQEALIMKDFHHSNV 439
Query: 73 VRLHD-SISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQ---QILEAVLHCHQ 128
+ L ++ + ++ + G+L I R+ + I I + +
Sbjct: 438 LTLIGICLNLDDMPLVVLPFMKHGDLLTYI--RDDQHQPTIKDLIMYGVDIARGMDYLAG 265
Query: 129 MGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPG-----YLSPE 183
+ VHRDL N +L VK+ADFGLA ++ ++ ++ +++ E
Sbjct: 264 LKFVHRDLAARNCMLDEDFH---VKVADFGLARDIY--EKEYYSSENKKAKLPVKWMALE 100
Query: 184 VLRKDPYGKPVDLWACGVILYILL 207
L K Y D+W+ GV+L+ LL
Sbjct: 99 SLEKGNYDSKTDVWSYGVVLWELL 28
>00715
Length = 1788
Score = 48.1 bits (113), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 50/200 (25%), Positives = 85/200 (42%), Gaps = 30/200 (15%)
Frame = +1
Query: 67 LKHPNIVRLHDSIS----EEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQ---QI 119
L+H N+V + + S E+G +L + V G L + ++ + D+S + Q+
Sbjct: 97 LRHVNVVSILGATSLHRFEDGA-WLAMEYV--GPLNLQTILNDHQQDIDSSMRLSLALQM 267
Query: 120 LEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLA------------------- 160
+ + H + +VH DLKP N LL LK +++ADFG
Sbjct: 268 ARGLHYLHSINIVHLDLKPANCLLTRDLK---LRIADFGCCHQLTPTGLDMGEREGGMAG 438
Query: 161 --IEVEGEQQAWFG-FAGTPGYLSPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDED 217
+E+ Q AW AGT Y +PE+L+ D+++ G+ L+ + P+
Sbjct: 439 NELELTPVQGAWKNELAGTLAYRAPELLKGLQPSVRSDVYSLGITLWQMCTRQGPYEGVP 618
Query: 218 QHR-LYQQIKAGAYDFPSPE 236
H +YQ + P P
Sbjct: 619 AHAVVYQVVSKDLRPCPPPS 678
>11780
Length = 1713
Score = 47.0 bits (110), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 43/152 (28%), Positives = 72/152 (47%), Gaps = 2/152 (1%)
Frame = +3
Query: 11 EEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLKHP 70
++ ++ E +GKG F V + + GQ A K + K R Q +EA + L+H
Sbjct: 597 QDLEIGEAIGKGDFGDVYK--GMYRGQPVAIKQLKDKD---RGEQSFLQEASVMTSLRHD 761
Query: 71 NIVRLHDSISEEGHHYLIFDLVTGGELFEDIVA--REYYSEADASHCIQQILEAVLHCHQ 128
N+VRL + E +L+ + + G L E + + R ++ D + A+ +
Sbjct: 762 NLVRLIGVVLGE-TIFLVTEFMGKGNLVEYLRSRGRSVITKKDQINFATDTCAAMEYLES 938
Query: 129 MGVVHRDLKPENLLLASKLKGAAVKLADFGLA 160
+VHRDL N+L+ K K++DFGLA
Sbjct: 939 KRLVHRDLAARNVLVHDDGK---AKVSDFGLA 1025
>36481
Length = 806
Score = 46.6 bits (109), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 45/150 (30%), Positives = 66/150 (44%), Gaps = 7/150 (4%)
Frame = +2
Query: 2 ATITCTRFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKII-NTKKLSARDHQKLERE 60
T+ T T + +L G+G F V +C +L G + A KII N K R+ KLE
Sbjct: 335 CTMRGTSSTNDMKLCPHWGEGTFGKVVQCKDLLKGDDIALKIIKNVDKY--REAAKLEIN 508
Query: 61 ARICRLLKHPN----IVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREY--YSEADASH 114
K P+ V++ D GH + F ++ G +F+ + Y Y H
Sbjct: 509 VLEKLREKDPHAKHMCVQMLDWFDYHGHVCISFHML-GLSVFDFLKDNSYGAYPIEQVRH 685
Query: 115 CIQQILEAVLHCHQMGVVHRDLKPENLLLA 144
Q+ AV H+ + H DLKPEN+L
Sbjct: 686 ISYQLCYAVNFLHENQLTHTDLKPENILFV 775
>00394
Length = 548
Score = 46.2 bits (108), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 27/86 (31%), Positives = 44/86 (51%), Gaps = 5/86 (5%)
Frame = -2
Query: 17 EELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLH 76
+E+G+G+F V + + G A + KK + + Q+ + EA + + L+HPNIVR
Sbjct: 280 KEIGRGSFKTVYKGLDTELGVAVAWCELQDKKWNKAERQRFKEEAEMLKELQHPNIVRFF 101
Query: 77 DSISEEGHH-----YLIFDLVTGGEL 97
D E H L+ +L+T G L
Sbjct: 100 DYWEEHNHRNRKVIILVTELMTSGTL 23
>31789
Length = 676
Score = 45.4 bits (106), Expect = 5e-05, Method: Compositional matrix adjust.
Identities = 27/85 (31%), Positives = 43/85 (50%), Gaps = 5/85 (5%)
Frame = +2
Query: 18 ELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHD 77
E+G+G+F V + + G A + KK + + Q+ + EA + + L+HPNIVR D
Sbjct: 341 EIGRGSFKTVYKGLDTELGVAVAWCELQDKKWNKTERQRFKEEAEMLKELQHPNIVRFFD 520
Query: 78 SISEEGHH-----YLIFDLVTGGEL 97
E H L+ +L+T G L
Sbjct: 521 YWEEHNHRNRKVIILVTELMTSGTL 595
>07291
Length = 833
Score = 43.9 bits (102), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 29/118 (24%), Positives = 60/118 (50%), Gaps = 6/118 (5%)
Frame = +1
Query: 117 QQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGT 176
+QI + + + ++ VVHR+L N ++ + ++L+D+G+ + Q+++ +
Sbjct: 70 RQIADGMAYLQEVKVVHRNLAARNCIVT---EDGRLQLSDYGVTGSLF--PQSYYTADDS 234
Query: 177 PG-----YLSPEVLRKDPYGKPVDLWACGVILYILLV-GYPPFWDEDQHRLYQQIKAG 228
P +++PE + + D+WA GV+L+ LL G P+ D + L +K G
Sbjct: 235 PARDLVKWMAPETIDNFHFSSKSDVWAFGVVLWELLTRGITPYPDVENSSLLPYLKEG 408
>31489
Length = 329
Score = 43.9 bits (102), Expect = 1e-04, Method: Composition-based stats.
Identities = 27/87 (31%), Positives = 48/87 (55%), Gaps = 6/87 (6%)
Frame = +3
Query: 62 RICRLLKHPNIVRLHDSIS-EEGHH-----YLIFDLVTGGELFEDIVAREYYSEADASHC 115
+I + KH NI+ + + + ++ +H +++FDL+ +L I + + +E +
Sbjct: 6 KILKHFKHDNIISIREILKPKDSYHDFKDIHVVFDLMES-DLHRIIYSDQPLTEEHIRYF 182
Query: 116 IQQILEAVLHCHQMGVVHRDLKPENLL 142
+ QIL + + H VVHRDLKP NLL
Sbjct: 183 LYQILRGLKYIHSANVVHRDLKPSNLL 263
>25019
Length = 730
Score = 43.9 bits (102), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 26/62 (41%), Positives = 34/62 (54%)
Frame = +3
Query: 139 ENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDLWA 198
EN+LL K VKL DFGL E + F GT Y++PE+L + +GK VD W+
Sbjct: 261 ENVLLD---KDGHVKLTDFGLCKEAITGTRVTHTFCGTIEYMAPEILTRTGHGKAVDWWS 431
Query: 199 CG 200
G
Sbjct: 432 LG 437
>18481
Length = 437
Score = 42.0 bits (97), Expect = 6e-04, Method: Compositional matrix adjust.
Identities = 35/130 (26%), Positives = 65/130 (50%), Gaps = 5/130 (3%)
Frame = -1
Query: 36 GQEYAAKI--INTKKLSARDHQKLEREARIC-RLLKHPNIVRLHDSISEEGHHYLIFDLV 92
G++ A KI I+ K HQ L EA++ ++ +HP + ++ +E+ + L+ +L+
Sbjct: 410 GKDIAVKIEAIDVK------HQLLHYEAKVYEQIGRHPGLPTMYHYGTEKHFNALVMELL 249
Query: 93 TGG--ELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGA 150
ELF ++ + ++ Q+L + HQ +HRDLKP+N L+
Sbjct: 248 GPSLEELF--VICKRRFTLKTILMVSDQLLSRLEFIHQKCFIHRDLKPDNFLMGLGRHCH 75
Query: 151 AVKLADFGLA 160
+ + DFGL+
Sbjct: 74 RLYIIDFGLS 45
>32957
Length = 645
Score = 40.8 bits (94), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 21/51 (41%), Positives = 29/51 (56%)
Frame = +3
Query: 157 FGLAIEVEGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDLWACGVILYILL 207
F L +E G + F GT Y++PEV + YGK VD W G++L+ LL
Sbjct: 3 FALCVEKSGGRTR--TFCGTREYMAPEVHERKEYGKEVDWWGLGILLHELL 149
>12672
Length = 773
Score = 40.4 bits (93), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 29/98 (29%), Positives = 48/98 (48%), Gaps = 4/98 (4%)
Frame = +3
Query: 116 IQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEV---EGEQ-QAWF 171
++ + + + G VHRD+K N+LL S+ K+ DF + EG+ Q
Sbjct: 9 VKGTASGIQYLNDNGHVHRDIKTANILLDSEYTA---KVGDFATVVSAPSGEGKTVQNAS 179
Query: 172 GFAGTPGYLSPEVLRKDPYGKPVDLWACGVILYILLVG 209
GT YL+PE + D K +D ++ GV+L ++ G
Sbjct: 180 VVIGTAAYLAPEAIHFDVSTK-LDSYSFGVVLLEVITG 290
>07940
Length = 1336
Score = 40.4 bits (93), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 30/102 (29%), Positives = 50/102 (49%), Gaps = 6/102 (5%)
Frame = -3
Query: 118 QILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTP 177
Q+ + + +HRDL N+L+A + +K+ADFGL + QQ + T
Sbjct: 323 QVARGMEYLASKQCIHRDLAARNVLVAEEY---VLKIADFGLTRNL---QQFDYYRKTTD 162
Query: 178 G-----YLSPEVLRKDPYGKPVDLWACGVILY-ILLVGYPPF 213
G +++PE L Y D+W+ GV+L+ I +G P+
Sbjct: 161 GRLPVKWMAPEALFDRKYTSKSDVWSYGVLLWEIFTLGGNPY 36
>01106
Length = 878
Score = 40.4 bits (93), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 39/148 (26%), Positives = 67/148 (45%), Gaps = 12/148 (8%)
Frame = +3
Query: 9 FTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKL---SARDHQKLEREARICR 65
F Y + +LG G FS V C + + A K++ + + +A D KL + R
Sbjct: 312 FNGRYHVIRKLGWGHFSTVWLCWDLTCKRFVALKVVKSAQHYTETALDEVKLLKCVRESD 491
Query: 66 LLK--HPNIVRLHDSISEEG----HHYLIFDLVTGGELFEDIVAREYYSEA--DASHCIQ 117
+ V+L D G H ++F+ V G L + I+ Y + I+
Sbjct: 492 VADPARAKCVQLLDDFKISGVNGTHVAMVFE-VLGYNLLKLIIRSNYQGIPIHNVKLIIR 668
Query: 118 QILEAVLHCH-QMGVVHRDLKPENLLLA 144
Q+LE + + H + ++H D+KPEN+L+
Sbjct: 669 QVLEGLSYMHAKCRIIHTDIKPENILIC 752
>08294
Length = 1849
Score = 39.7 bits (91), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 54/212 (25%), Positives = 86/212 (40%), Gaps = 17/212 (8%)
Frame = +2
Query: 70 PNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVA-REYYSEADASHCI-----------Q 117
PNIV E H+LI + G+L + ++A R + Q
Sbjct: 887 PNIVHFMGVCREAEPHFLITEYCDWGDLKQFLLATRNDNGRGRGTRVPALALSQKLGMGQ 1066
Query: 118 QILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTP 177
Q+ + G+VH DL N+LL S+++ +K+A L+ +V + P
Sbjct: 1067 QVAAGMEALSNQGLVHGDLAARNVLLTSRMQ---LKVARPALSGDVYASEYYPLHQRLVP 1237
Query: 178 -GYLSPEVLRKDPYGKPVDLWACGVILYILL----VGYPPFWDEDQHRLYQQIKAGAYDF 232
+L PE + +D D+WA GV L+ +L + Y DE+ R Q +A A D
Sbjct: 1238 LRWLPPEGVLEDSATTCGDVWAFGVFLWEVLQLADLPYRLMSDEEVLRSLQHSQA-ALDS 1414
Query: 233 PSPEWDTVTPEAKDLINKMLTINPSKRITAAE 264
P P L+ + PS+R +E
Sbjct: 1415 PD-----APPALLSLLQRCTAQQPSQRPPFSE 1495
>29360
Length = 363
Score = 39.7 bits (91), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 21/77 (27%), Positives = 38/77 (49%), Gaps = 3/77 (3%)
Frame = +3
Query: 71 NIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHC---IQQILEAVLHCH 127
N VR + + H L+F+++ D + + + + QQ+L A+
Sbjct: 138 NFVRAFECFQHKNHTCLVFEMLEQN--LYDFLKQNKFQPLPLKYIRPITQQVLTALRKLK 311
Query: 128 QMGVVHRDLKPENLLLA 144
Q+G++H DLKPEN++L
Sbjct: 312 QLGLIHADLKPENIMLV 362
>18287
Length = 678
Score = 39.3 bits (90), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 20/42 (47%), Positives = 26/42 (61%), Gaps = 1/42 (2%)
Frame = -3
Query: 241 TPEAKDLINKMLTINPSKRITAAEALKHPWISH-RSTVASCM 281
T EA L+ +ML +NP RI+A EAL HP++ R SCM
Sbjct: 436 THEAVRLLTRMLILNPKNRISAEEALSHPYLDEGRVRFHSCM 311
>11404
Length = 563
Score = 38.9 bits (89), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 37/149 (24%), Positives = 67/149 (44%), Gaps = 11/149 (7%)
Frame = +1
Query: 8 RFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLL 67
++ + Y++ +GKG+F V + ++ A KII KK Q E ++ ++
Sbjct: 130 KWADRYEIDSLIGKGSFGQVVKAYDHTDNEQVAIKIIKNKKPFLNQAQI---EVKLLEMM 300
Query: 68 KHPN------IVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADAS---HCIQQ 118
+ IVRL H L+F+L++ D++ + + QQ
Sbjct: 301 NRHDTDNKYYIVRLKRHFMFRSHLCLVFELLSYN--LYDLLRNTNFRGVSLNLTRKFAQQ 474
Query: 119 ILEAVLHCH--QMGVVHRDLKPENLLLAS 145
+ A+L +M ++H DLKPEN+LL +
Sbjct: 475 LCTALLFLATPEMSIIHCDLKPENILLCN 561
>23319
Length = 2235
Score = 38.5 bits (88), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 31/117 (26%), Positives = 51/117 (43%), Gaps = 26/117 (22%)
Frame = +3
Query: 182 PEVLRKDPYGKPVDLWACGVILYILLVGYPPFW----DEDQ-HRLYQQIKAGAYD----- 231
P+V Y +D+W+ G I L P + D+DQ R+++ + D
Sbjct: 3 PDVYXAKMYSTSIDMWSAGCIFAELANAGRPLFPGNDDDDQLKRIFKLLGTPTEDQWPGM 182
Query: 232 --------FP----SPEWDTVTPE----AKDLINKMLTINPSKRITAAEALKHPWIS 272
FP + W V P+ +DL+ +L PS R++A EAL+HP+ +
Sbjct: 183 TQLPNYRMFPMYHVTTTWQQVVPKLNSKGRDLLQCLLVCCPSDRMSADEALQHPYFA 353
>18401
Length = 463
Score = 38.1 bits (87), Expect = 0.009, Method: Compositional matrix adjust.
Identities = 31/140 (22%), Positives = 52/140 (37%), Gaps = 41/140 (29%)
Frame = -3
Query: 174 AGTPGYLSPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQ--------------- 218
T Y +PEV+ + + P D+W+ G I++ L GY F D
Sbjct: 449 VSTRHYRAPEVILELGWSHPCDVWSVGCIMFELYTGYTLFQTHDNKEHLAMMERILGSLP 270
Query: 219 HRLYQQIKAGAY----DFPSPEWDTVTPEAK----------------------DLINKML 252
+R+ ++ K Y PE ++ + DL+ K+L
Sbjct: 269 YRMAKKTKKQKYFHHGRLDVPERSSMARYVRENTKPLLRYVKDRENKDHQQLFDLMKKLL 90
Query: 253 TINPSKRITAAEALKHPWIS 272
S R + +AL+HP+ S
Sbjct: 89 AYEASSRYSLLQALQHPFFS 30
>20513
Length = 405
Score = 37.4 bits (85), Expect = 0.015, Method: Compositional matrix adjust.
Identities = 16/37 (43%), Positives = 24/37 (64%), Gaps = 1/37 (2%)
Frame = -1
Query: 236 EWDTVTPEA-KDLINKMLTINPSKRITAAEALKHPWI 271
EWD +A D + ML +P +R TAA++L+HPW+
Sbjct: 315 EWDPKDAKAFADFLAPMLEFDPEQRATAAQSLQHPWL 205
>37063
Length = 455
Score = 37.0 bits (84), Expect = 0.016, Method: Composition-based stats.
Identities = 26/83 (31%), Positives = 42/83 (50%), Gaps = 10/83 (12%)
Frame = -2
Query: 136 LKPENLLLASKLKGAAVKLADFGLA--IEVEGE---QQAWFGFAGTPGYLSPEVL----- 185
LKPEN+L + +K+ DF LA I +G+ G+ Y++PEV+
Sbjct: 454 LKPENILCEHLDEVVPLKICDFDLASGINCDGDGTKTPELLTPVGSAEYMAPEVVDAWVG 275
Query: 186 RKDPYGKPVDLWACGVILYILLV 208
Y K D+W+ G+IL +L++
Sbjct: 274 ESFSYDKRCDMWSLGIIL*VLVM 206
>16350
Length = 1108
Score = 37.0 bits (84), Expect = 0.019, Method: Compositional matrix adjust.
Identities = 16/37 (43%), Positives = 24/37 (64%), Gaps = 1/37 (2%)
Frame = +3
Query: 236 EWDTVTPEA-KDLINKMLTINPSKRITAAEALKHPWI 271
EWD +A D + ML +P +R TAA++L+HPW+
Sbjct: 729 EWDPKDAKAFADFLAPMLEFDPEQRATAAQSLQHPWL 839
>18996
Length = 491
Score = 36.6 bits (83), Expect = 0.025, Method: Compositional matrix adjust.
Identities = 22/79 (27%), Positives = 39/79 (49%), Gaps = 3/79 (3%)
Frame = +2
Query: 132 VHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTP---GYLSPEVLRKD 188
+HRDL N+L+ + VK++DFGLA + ++G + + SPE +
Sbjct: 2 IHRDLAARNILVDR----SCVKISDFGLA-QFANADGYYYGISQRDIPIKWYSPEAIETC 166
Query: 189 PYGKPVDLWACGVILYILL 207
+ D+W+ GV L+ +
Sbjct: 167 KFSSYSDVWSYGVTLFEMF 223
>15549
Length = 470
Score = 35.8 bits (81), Expect = 0.039, Method: Compositional matrix adjust.
Identities = 15/38 (39%), Positives = 24/38 (63%)
Frame = -1
Query: 7 TRFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKII 44
+RF +E++ E++GKG + +V R + QEYA K I
Sbjct: 230 SRFADEFECIEQMGKGGYGIVFRAKNKVDEQEYAVKRI 117
>07836
Length = 1478
Score = 35.4 bits (80), Expect = 0.054, Method: Compositional matrix adjust.
Identities = 46/165 (27%), Positives = 73/165 (44%), Gaps = 26/165 (15%)
Frame = -1
Query: 66 LLKHPNIVR-LHDSISEEG---HHYLIFDLVTGGELFEDIVAR-----EYYSEADASHCI 116
LL+H NI+ + I G +LI D G L + +++R E + A ++ C
Sbjct: 1397 LLRHENILGFIAADIKGTGSWTQLFLITDYHENGSLHDYLLSRVLDSSEMLALAHSAICG 1218
Query: 117 QQILEAVLHCHQMG------VVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQ-- 168
A LH G + HRD+K +N+L+ K +AD GLA+ E
Sbjct: 1217 L----AHLHIEIFGTRGKPAIAHRDIKSKNILVK---KNGTCCIADLGLAVRYISESNEV 1059
Query: 169 --AWFGFAGTPGYLSPEVLRK-------DPYGKPVDLWACGVILY 204
A GT Y++PEVL D + K D++A G++++
Sbjct: 1058 DVAPNPRQGTKRYMAPEVLEMLLNVKNFDAF-KQADMYAFGLVMW 927
>16708
Length = 1397
Score = 35.4 bits (80), Expect = 0.058, Method: Compositional matrix adjust.
Identities = 19/47 (40%), Positives = 30/47 (63%), Gaps = 1/47 (2%)
Frame = -1
Query: 115 CIQ-QILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLA 160
CI Q + A+ H H++GVVH D+K +N+L+ + KL D+G+A
Sbjct: 1082 CIAGQXVCALEHIHELGVVHMDVKADNVLVDAH---GNCKLTDYGIA 951
>00638
Length = 1595
Score = 35.4 bits (80), Expect = 0.058, Method: Compositional matrix adjust.
Identities = 11/32 (34%), Positives = 23/32 (71%)
Frame = +2
Query: 107 YSEADASHCIQQILEAVLHCHQMGVVHRDLKP 138
+++ D + ++++A+ CH MG++HRD+KP
Sbjct: 407 FTDYDIRFYLYELMKALDFCHSMGIMHRDVKP 502
>20160
Length = 1277
Score = 34.7 bits (78), Expect = 0.094, Method: Compositional matrix adjust.
Identities = 13/30 (43%), Positives = 21/30 (70%)
Frame = +2
Query: 243 EAKDLINKMLTINPSKRITAAEALKHPWIS 272
+A DLIN+ + ++PS R A+ LKH W++
Sbjct: 335 DAADLINRCIALDPSTRPVLADILKHKWMT 424
>37602
Length = 804
Score = 33.9 bits (76), Expect = 0.15, Method: Compositional matrix adjust.
Identities = 28/118 (23%), Positives = 50/118 (42%), Gaps = 5/118 (4%)
Frame = -1
Query: 65 RLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVL 124
R++ V DS ++ + GG + + +E + ++ L+ +
Sbjct: 354 RIVNIQTFVGYFDSYLRREKLWIAMEYCGGGSMQDIYHVTGPLTEPQIAFVCRETLKGLH 175
Query: 125 HCHQMGVVHRDLKPENLLLASKLKGAAVKLADF-----GLAIEVEGEQQAWFGFAGTP 177
+ H+ G +HRD+K N+LL + VKLADF + V+ + W F G P
Sbjct: 174 YLHRRGKMHRDIKGANILLTEE---GDVKLADFWRVSSNHSHNVQKKVFHWNAFIGWP 10
>32359
Length = 928
Score = 33.5 bits (75), Expect = 0.21, Method: Compositional matrix adjust.
Identities = 22/62 (35%), Positives = 33/62 (53%), Gaps = 5/62 (8%)
Frame = -1
Query: 19 LGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSA-----RDHQKLEREARICRLLKHPNIV 73
+G G+F VV Y AK+++T +L A +D + RE +I R L+H NIV
Sbjct: 406 IGNGSFGVV-----------YQAKLVDTSELVAIKKVLQDKRFKNRELQIMRKLEHQNIV 260
Query: 74 RL 75
+L
Sbjct: 259 KL 254
Score = 28.1 bits (61), Expect = 7.3, Method: Compositional matrix adjust.
Identities = 11/14 (78%), Positives = 13/14 (92%)
Frame = -3
Query: 130 GVVHRDLKPENLLL 143
GV HRD+KP+NLLL
Sbjct: 65 GVCHRDIKPQNLLL 24
>35032
Length = 465
Score = 33.1 bits (74), Expect = 0.27, Method: Composition-based stats.
Identities = 12/26 (46%), Positives = 19/26 (73%)
Frame = +3
Query: 246 DLINKMLTINPSKRITAAEALKHPWI 271
DL+ ++L +PSKR+T AL HP++
Sbjct: 147 DLVKRLLNYDPSKRLTPXXALAHPFL 224
>26009
Length = 886
Score = 32.7 bits (73), Expect = 0.29, Method: Compositional matrix adjust.
Identities = 13/33 (39%), Positives = 23/33 (69%)
Frame = +3
Query: 111 DASHCIQQILEAVLHCHQMGVVHRDLKPENLLL 143
+A ++Q++ A+ H +VHRD+KPEN+L+
Sbjct: 714 EAKSVMKQLVSALDFMHSKQLVHRDIKPENVLI 812
>20559
Length = 430
Score = 32.3 bits (72), Expect = 0.38, Method: Compositional matrix adjust.
Identities = 24/84 (28%), Positives = 41/84 (48%), Gaps = 5/84 (5%)
Frame = -2
Query: 11 EEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQK-----LEREARICR 65
++Y+ E++G+G + V + A +I+ K++ D + RE + +
Sbjct: 375 QKYEKLEKIGEGTYGTVFK-----AKNRETHEIVALKRVRLDDDDEGVPSSALREICLLK 211
Query: 66 LLKHPNIVRLHDSISEEGHHYLIF 89
LKH NIVRLHD + E L+F
Sbjct: 210 ELKHRNIVRLHDVLHSERKLTLVF 139
>17516
Length = 453
Score = 32.3 bits (72), Expect = 0.44, Method: Composition-based stats.
Identities = 16/38 (42%), Positives = 24/38 (63%), Gaps = 1/38 (2%)
Frame = -3
Query: 173 FAGTPGYLSPEV-LRKDPYGKPVDLWACGVILYILLVG 209
AGTP Y++PEV L+K Y D+++ +IL+ L G
Sbjct: 439 LAGTPVYMAPEVLLQKGQYDMKADVYSLAIILWELWYG 326
>33586
Length = 551
Score = 32.3 bits (72), Expect = 0.48, Method: Compositional matrix adjust.
Identities = 15/48 (31%), Positives = 25/48 (52%)
Frame = +2
Query: 72 IVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQI 119
IV LH + EG YLI + + GG+LF + ++E D + ++
Sbjct: 407 IVHLHYAFQTEGKLYLILEFLRGGDLFTRLSKEVMFTEEDVKFYLAEL 550
>21800
Length = 855
Score = 31.6 bits (70), Expect = 0.76, Method: Compositional matrix adjust.
Identities = 23/79 (29%), Positives = 40/79 (50%), Gaps = 7/79 (8%)
Frame = +2
Query: 73 VRLHDSISEEG----HHYLIFDLVTGGELFEDIVAREYYSEA--DASHCIQQILEAVLHC 126
V+L D G H ++F+ V G L + I+ Y + I+Q+LE + +
Sbjct: 506 VQLLDDFKISGVNGTHVCMVFE-VLGYNLLKLIIRSNYQGIPVHNVKLIIRQVLEGLNYL 682
Query: 127 H-QMGVVHRDLKPENLLLA 144
H + ++H D+KPEN+L+
Sbjct: 683 HAKCNIIHTDIKPENILIC 739
>03106
Length = 2384
Score = 31.6 bits (70), Expect = 0.76, Method: Compositional matrix adjust.
Identities = 23/72 (31%), Positives = 33/72 (45%), Gaps = 1/72 (1%)
Frame = +2
Query: 195 DLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEA-KDLINKMLT 253
D+WA G + Y + PF+ Y Q +D PS D TPE L+ ML
Sbjct: 32 DVWAAGAVAYEIFGASNPFYSRLDSACYSQ-----HDLPSLPGD--TPEGVVRLVTSMLE 190
Query: 254 INPSKRITAAEA 265
+P++R +A A
Sbjct: 191 RDPAQRPSAVVA 226
>13305
Length = 549
Score = 30.8 bits (68), Expect = 1.4, Method: Compositional matrix adjust.
Identities = 15/51 (29%), Positives = 28/51 (54%), Gaps = 1/51 (1%)
Frame = +2
Query: 179 YLSPEVLRKDPYGKPVDLWACGVILY-ILLVGYPPFWDEDQHRLYQQIKAG 228
+++ E L + Y D+W+ GV+L+ I +G P+ D +L+ +K G
Sbjct: 23 WMAVESLFNNTYTTQSDVWSFGVVLWEIFTLGGTPYSSTDTQQLFAFLKDG 175
>03294
Length = 1684
Score = 30.0 bits (66), Expect = 2.1, Method: Compositional matrix adjust.
Identities = 27/109 (24%), Positives = 48/109 (44%), Gaps = 25/109 (22%)
Frame = -1
Query: 193 PVDLWACGVILYILLVGYPPF-WDEDQHRLYQQI---------------KAGAYDFPSPE 236
PVD+W+ G I +L+ P F D + +L++ K A++ P
Sbjct: 1675 PVDVWSIGTIFADMLIRTPIFKGDSEIDQLFKIFRIIGTPTEQTWPEFHKLPAFNGMFPL 1496
Query: 237 W------DTVT---PEAKDLINKMLTINPSKRITAAEALKHPWISHRST 276
W +T+T DLI + L +P++RI+ + L+H + + T
Sbjct: 1495 WKEGKLSETLTDLDSLGLDLIERTLKCDPAQRISCKKMLQHAYFLNVDT 1349
>28494
Length = 463
Score = 29.6 bits (65), Expect = 2.7, Method: Composition-based stats.
Identities = 18/54 (33%), Positives = 24/54 (44%)
Frame = +3
Query: 242 PEAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNA 295
P NK L I+ + A + HP +SH ST A C R T+ L +A
Sbjct: 39 PPLAPFSNKYLAISVKPQDAVAWSGVHPSLSHTSTSAFCSTRNSTMSRLSSMHA 200
>17011
Length = 1371
Score = 29.3 bits (64), Expect = 3.3, Method: Compositional matrix adjust.
Identities = 12/26 (46%), Positives = 17/26 (65%)
Frame = +1
Query: 246 DLINKMLTINPSKRITAAEALKHPWI 271
DLI ++T NP R+T AL HP++
Sbjct: 1 DLILDVVTFNPDHRLTPDLALSHPFL 78
>14104
Length = 573
Score = 28.9 bits (63), Expect = 5.2, Method: Compositional matrix adjust.
Identities = 9/36 (25%), Positives = 22/36 (61%)
Frame = +1
Query: 236 EWDTVTPEAKDLINKMLTINPSKRITAAEALKHPWI 271
++ P+A + L ++P++R+T + L+HP++
Sbjct: 76 KFSNAAPQAMSFMQSCLKMDPAERLTCHQLLQHPYM 183
>32357
Length = 625
Score = 28.5 bits (62), Expect = 6.2, Method: Compositional matrix adjust.
Identities = 16/57 (28%), Positives = 33/57 (57%)
Frame = -2
Query: 12 EYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLK 68
+Y+L +++G G+F + V +G+E A K+ +L H +L E+++ R+L+
Sbjct: 435 KYRLMKKIGSGSFGEIYLGVHNTSGEEVAVKL----ELKNAKHPQLYYESKLYRVLQ 277
>32691
Length = 295
Score = 28.1 bits (61), Expect = 9.1, Method: Composition-based stats.
Identities = 14/36 (38%), Positives = 20/36 (55%)
Frame = +1
Query: 236 EWDTVTPEAKDLINKMLTINPSKRITAAEALKHPWI 271
+W T E D ++K L NP R TA + L+H +I
Sbjct: 82 KWST---EFIDFVSKCLVKNPENRATAVDLLQHDFI 180
BLAST Search Results
TBLASTN 2.2.18 [Mar-02-2008]