Publications from 1998

Research highlights at the chemistry/biology interface.
Gerlt JA, Marletta MA.
Curr Opin Chem Biol. 1998 Oct;2(5):605-606. No abstract available. Pubmed

Mechanistically diverse enzyme superfamilies: the importance of chemistry in the evolution of catalysis.
Gerlt JA, Babbitt PC.
Curr Opin Chem Biol. 1998 Oct;2(5):607-12. Review. Pubmed

Evolution of enzymatic activities in the enolase superfamily: characterization of the (D)-glucarate/galactarate catabolic pathway in Escherichia coli.
Hubbard BK, Koch M, Palmer DR, Babbitt PC, Gerlt JA.
Biochemistry. 1998 Oct 13;37(41):14369-75. Pubmed

Evolution of enzymatic activities in the enolase superfamily: crystal structure of (D)-glucarate dehydratase from Pseudomonas putida.
Gulick AM, Palmer DR, Babbitt PC, Gerlt JA, Rayment I.
Biochemistry. 1998 Oct 13;37(41):14358-68. Pubmed

Evolution of enzymatic activities in the enolase superfamily: partitioning of reactive intermediates by (D)-glucarate dehydratase from Pseudomonas putida.
Palmer DR, Hubbard BK, Gerlt JA.
Biochemistry. 1998 Oct 13;37(41):14350-7. Pubmed

The low barrier hydrogen bond in enzymatic catalysis.
Cleland WW, Frey PA, Gerlt JA.
J Biol Chem. 1998 Oct 2;273(40):25529-32. Review. No abstract available. Pubmed

Evolution of an enzyme active site: the structure of a new crystal form of muconate lactonizing enzyme compared with mandelate racemase and enolase.
Hasson MS, Schlichting I, Moulai J, Taylor K, Barrett W, Kenyon GL, Babbitt PC, Gerlt JA, Petsko GA, Ringe D.
Proc Natl Acad Sci U S A. 1998 Sep 1;95(18):10396-401. Pubmed

The crystal structure of benzoylformate decarboxylase at 1.6 A resolution: diversity of catalytic residues in thiamin diphosphate-dependent enzymes.
Hasson MS, Muscate A, McLeish MJ, Polovnikova LS, Gerlt JA, Kenyon GL, Petsko GA, Ringe D.
Biochemistry. 1998 Jul 14;37(28):9918-30. Pubmed