Publications from 2011

The Enzyme Function Initiative.
Gerlt JA, Allen KN, Almo SC, Armstrong RN, Babbitt PC, Cronan JE, Dunaway-Mariano D, Imker HJ, Jacobson MP, Minor W, Poulter CD, Raushel FM, Sali A, Shoichet BK, Sweedler JV.
Biochemistry. 2011 Nov 22;50(46):9950-62. Epub 2011 Oct 26. Review. Pubmed

Mechanism of the orotidine 5'-monophosphate decarboxylase-catalyzed reaction: importance of residues in the orotate binding site.
Iiams V, Desai BJ, Fedorov AA, Fedorov EV, Almo SC, Gerlt JA.
Biochemistry. 2011 Oct 4;50(39):8497-507. Epub 2011 Sep 6. Pubmed

OMP decarboxylase: phosphodianion binding energy is used to stabilize a vinyl carbanion intermediate.
Goryanova B, Amyes TL, Gerlt JA, Richard JP.
J Am Chem Soc. 2011 May 4;133(17):6545-8. Epub 2011 Apr 12. Pubmed