Publications from 2007

Evolutionary potential of (beta/alpha)8-barrels: stepwise evolution of a "new" reaction in the enolase superfamily.
Vick JE, Gerlt JA.
Biochemistry. 2007 Dec 18;46(50):14589-97. Epub 2007 Nov 20. Pubmed

A Protein Structure (or Function ?) Initiative.
Gerlt JA.
Structure. 2007 Nov;15(11):1353-6. No abstract available. Pubmed

Evolution of enzymatic activities in the enolase superfamily: D-Mannonate dehydratase from Novosphingobium aromaticivorans.
Rakus JF, Fedorov AA, Fedorov EV, Glasner ME, Vick JE, Babbitt PC, Almo SC, Gerlt JA.
Biochemistry. 2007 Nov 13;46(45):12896-908. Epub 2007 Oct 18. Pubmed

Product deuterium isotope effect for orotidine 5'-monophosphate decarboxylase: evidence for the existence of a short-lived carbanion intermediate.
Toth K, Amyes TL, Wood BM, Chan K, Gerlt JA, Richard JP.
J Am Chem Soc. 2007 Oct 31;129(43):12946-7. Epub 2007 Oct 5. No abstract available. Pubmed

Evolution of enzymatic activities in the enolase superfamily: L-talarate/galactarate dehydratase from Salmonella typhimurium LT2.
Yew WS, Fedorov AA, Fedorov EV, Almo SC, Gerlt JA.
Biochemistry. 2007 Aug 21;46(33):9564-77. Epub 2007 Jul 25. Pubmed

Prediction and assignment of function for a divergent N-succinyl amino acid racemase.
Song L, Kalyanaraman C, Fedorov AA, Fedorov EV, Glasner ME, Brown S, Imker HJ, Babbitt PC, Almo SC, Jacobson MP, Gerlt JA.
Nat Chem Biol. 2007 Aug;3(8):486-91. Epub 2007 Jul 1. Pubmed

Obituary: Frank H. Westheimer (1912-2007).
Gerlt JA.
Nature. 2007 May 31;447(7144):543. No abstract available. Pubmed

Mechanistic diversity in the RuBisCO superfamily: the "enolase" in the methionine salvage pathway in Geobacillus kaustophilus.
Imker HJ, Fedorov AA, Fedorov EV, Almo SC, Gerlt JA.
Biochemistry. 2007 Apr 3;46(13):4077-89. Epub 2007 Mar 13. Pubmed

Mechanisms of protein evolution and their application to protein engineering.
Glasner ME, Gerlt JA, Babbitt PC.
Adv Enzymol Relat Areas Mol Biol. 2007;75:193-239, xii-xiii. Review. Pubmed