Publications from 2005

Evolutionary potential of (beta/alpha)8-barrels: in vitro enhancement of a "new" reaction in the enolase superfamily.
Vick JE, Schmidt DM, Gerlt JA.
Biochemistry. 2005 Sep 6;44(35):11722-9. Pubmed

Evolution of enzymatic activities in the orotidine 5'-monophosphate decarboxylase suprafamily: structural basis for catalytic promiscuity in wild-type and designed mutants of 3-keto-L-gulonate 6-phosphate decarboxylase.
Wise EL, Yew WS, Akana J, Gerlt JA, Rayment I.
Biochemistry. 2005 Feb 15;44(6):1816-23. Pubmed

Evolution of enzymatic activities in the orotidine 5'-monophosphate decarboxylase suprafamily: enhancing the promiscuous D-arabino-hex-3-ulose 6-phosphate synthase reaction catalyzed by 3-keto-L-gulonate 6-phosphate decarboxylase.
Yew WS, Akana J, Wise EL, Rayment I, Gerlt JA.
Biochemistry. 2005 Feb 15;44(6):1807-15. Pubmed

Divergent evolution in the enolase superfamily: the interplay of mechanism and specificity.
Gerlt JA, Babbitt PC, Rayment I.
Arch Biochem Biophys. 2005 Jan 1;433(1):59-70. Review.